{"text_format":"3","workbook":"xlsx","n_sheets":12,"sheets":["Table 1","Table 2","Table 3","Table 4","Table 5","Table 6","Table 7","Table 8","Table 9","Table 10","Table 11","Table 12"],"read":"whole","date_system":"1900"}

{"sheet":"Table 1","index":0,"n_rows":29035,"n_cols":16,"rows_kept":4500,"cut":true,"bounds":{"rows_first":2000,"rows_last":500,"rows_between":2000,"halvings":0}}
["gene_id","gene_name","transcript_id","GO","KEGG","KO_ENTRY","EC","Description","FPKM.T2","FPKM.T1","fc","log2(fc)","pval","qval","regulation","significant"]
["MSTRG.321","PTAFR","ENST00000373857;ENST00000539896;ENST00000305392","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0004930(G-protein coupled receptor activity);GO:0007186(G-protein coupled receptor signaling pathway);GO:0005886(plasma membrane);GO:0004871(signal transducer activity);GO:0007165(signal transduction);GO:0006935(chemotaxis);GO:0035589(G-protein coupled purinergic nucleotide receptor signaling pathway);GO:0048015(phosphatidylinositol-mediated signaling);GO:0005887(integral component of plasma membrane);GO:0043312(neutrophil degranulation);GO:0070821(tertiary granule membrane);GO:0006954(inflammatory response);GO:0006955(immune response);GO:0030667(secretory granule membrane);GO:0005543(phospholipid binding);GO:0060333(interferon-gamma-mediated signaling pathway);GO:0045028(G-protein coupled purinergic nucleotide receptor activity);GO:0031663(lipopolysaccharide-mediated signaling pathway);GO:0004992(platelet activating factor receptor activity);GO:0001530(lipopolysaccharide binding);GO:0001875(lipopolysaccharide receptor activity);GO:0051019(mitogen-activated protein kinase binding);GO:0001816(cytokine production);GO:0002693(positive regulation of cellular extravasation);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0007567(parturition);GO:0009609(response to symbiotic bacterium);GO:0010863(positive regulation of phospholipase C activity);GO:0032496(response to lipopolysaccharide);GO:0032760(positive regulation of tumor necrosis factor production);GO:0032959(inositol trisphosphate biosynthetic process);GO:0043315(positive regulation of neutrophil degranulation);GO:0045056(transcytosis);GO:0045410(positive regulation of interleukin-6 biosynthetic process);GO:0045727(positive regulation of translation);GO:0045776(negative regulation of blood pressure);GO:0045907(positive regulation of vasoconstriction);GO:0045987(positive regulation of smooth muscle contraction);GO:0046683(response to organophosphorus);GO:0048661(positive regulation of smooth muscle cell proliferation);GO:0060732(positive regulation of inositol phosphate biosynthetic process);GO:0071258(cellular response to gravity);GO:0071320(cellular response to cAMP);GO:0071398(cellular response to fatty acid);GO:0071548(response to dexamethasone);GO:0097755(positive regulation of blood vessel diameter);GO:1902943(positive regulation of voltage-gated chloride channel activity);GO:1903039(positive regulation of leukocyte cell-cell adhesion);GO:1903238(positive regulation of leukocyte tethering or rolling);GO:1904058(positive regulation of sensory perception of pain);GO:1904300(positive regulation of transcytosis);GO:1904303(positive regulation of maternal process involved in parturition);GO:1904306(positive regulation of gastro-intestinal system smooth muscle contraction);GO:1904316(response to 2-O-acetyl-1-O-hexadecyl-sn-glycero-3-phosphocholine);GO:1904317(cellular response to 2-O-acetyl-1-O-hexadecyl-sn-glycero-3-phosphocholine);GO:1904317(cellular response to 2-O-acetyl-1-O-hexadecyl-sn-glycero-3-phosphocholine)","04020(Calcium signaling pathway);04080(Neuroactive ligand-receptor interaction);05150(Staphylococcus aureus infection);05150(Staphylococcus aureus infection)","K04279","NA","platelet activating factor receptor [Source:HGNC Symbol;Acc:HGNC:9582]",{"v":0.253740907139822,"d":"0.25"},{"v":38.0696313767531,"d":"38.07"},{"v":0.00666517898817289,"d":"0.01"},{"v":-7.22914066637977,"d":"-7.23"},{"v":9.01588375407501e-18,"d":"0.00"},{"v":1.04701458036073e-13,"d":"0.00"},"down","yes"]
["MSTRG.10876","CCR1","ENST00000296140","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0004930(G-protein coupled receptor activity);GO:0007186(G-protein coupled receptor signaling pathway);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0004871(signal transducer activity);GO:0007165(signal transduction);GO:0006955(immune response);GO:0006816(calcium ion transport);GO:0004950(chemokine receptor activity);GO:0016493(C-C chemokine receptor activity);GO:0006935(chemotaxis);GO:0006954(inflammatory response);GO:0070098(chemokine-mediated signaling pathway);GO:0090026(positive regulation of monocyte chemotaxis);GO:0004435(phosphatidylinositol phospholipase C activity);GO:0006887(exocytosis);GO:0005887(integral component of plasma membrane);GO:0010629(negative regulation of gene expression);GO:0070374(positive regulation of ERK1 and ERK2 cascade);GO:0007155(cell adhesion);GO:0007166(cell surface receptor signaling pathway);GO:0009611(response to wounding);GO:0030335(positive regulation of cell migration);GO:0007204(positive regulation of cytosolic calcium ion concentration);GO:0002407(dendritic cell chemotaxis);GO:0007267(cell-cell signaling);GO:0045672(positive regulation of osteoclast differentiation);GO:0051928(positive regulation of calcium ion transport);GO:0019221(cytokine-mediated signaling pathway);GO:0009897(external side of plasma membrane);GO:0006874(cellular calcium ion homeostasis);GO:0007187(G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger);GO:0030502(negative regulation of bone mineralization);GO:0019957(C-C chemokine binding);GO:0035717(chemokine (C-C motif) ligand 7 binding);GO:0071791(chemokine (C-C motif) ligand 5 binding)","04060(Cytokine-cytokine receptor interaction);04062(Chemokine signaling pathway);05167(Kaposi's sarcoma-associated herpesvirus infection)","K04176","NA","C-C motif chemokine receptor 1 [Source:HGNC Symbol;Acc:HGNC:1602]",{"v":45.869339,"d":"45.87"},{"v":0.311315,"d":"0.31"},{"v":147.340600356552,"d":"147.34"},{"v":7.20301121595406,"d":"7.20"},{"v":4.75717622369966e-16,"d":"0.00"},{"v":2.76225437429121E-12,"d":"0.00"},"up","yes"]
["MSTRG.7156","KCNJ2","ENST00000243457;ENST00000535240","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005244(voltage-gated ion channel activity);GO:0006811(ion transport);GO:0006813(potassium ion transport);GO:0034765(regulation of ion transmembrane transport);GO:0005242(inward rectifier potassium channel activity);GO:0005886(plasma membrane);GO:0005887(integral component of plasma membrane);GO:0061337(cardiac conduction);GO:0051289(protein homotetramerization);GO:0060306(regulation of membrane repolarization);GO:0090076(relaxation of skeletal muscle);GO:0031224(intrinsic component of membrane);GO:0008076(voltage-gated potassium channel complex);GO:0086002(cardiac muscle cell action potential involved in contraction);GO:0086091(regulation of heart rate by cardiac conduction);GO:0010107(potassium ion import);GO:0086012(membrane depolarization during cardiac muscle cell action potential);GO:0030007(cellular potassium ion homeostasis);GO:0055119(relaxation of cardiac muscle);GO:0086013(membrane repolarization during cardiac muscle cell action potential);GO:0086008(voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization);GO:0071805(potassium ion transmembrane transport);GO:0086011(membrane repolarization during action potential);GO:0005546(phosphatidylinositol-4,5-bisphosphate binding);GO:0015467(G-protein activated inward rectifier potassium channel activity);GO:0014861(regulation of skeletal muscle contraction via regulation of action potential);GO:0060075(regulation of resting membrane potential);GO:0042802(identical protein binding);GO:0015693(magnesium ion transport);GO:0071260(cellular response to mechanical stimulus);GO:0086001(cardiac muscle cell action potential);GO:0086004(regulation of cardiac muscle cell contraction);GO:1901381(positive regulation of potassium ion transmembrane transport);GO:0005790(smooth endoplasmic reticulum);GO:0005791(rough endoplasmic reticulum);GO:0005794(Golgi apparatus);GO:0014704(intercalated disc);GO:0030315(T-tubule);GO:0030425(dendrite);GO:0043025(neuronal cell body);GO:0043197(dendritic spine);GO:0043197(dendritic spine)","04921(Oxytocin signaling pathway);04924(Renin secretion);04971(Gastric acid secretion);04725(Cholinergic synapse);04725(Cholinergic synapse)","K04996","NA","potassium voltage-gated channel subfamily J member 2 [Source:HGNC Symbol;Acc:HGNC:6263]",{"v":0.155437911421911,"d":"0.16"},{"v":8.21236502492379,"d":"8.21"},{"v":0.0189273018125925,"d":"0.02"},{"v":-5.72338742791635,"d":"-5.72"},{"v":2.80743138408899E-13,"d":"0.00"},{"v":1.08675668878085e-09,"d":"0.00"},"down","yes"]
["MSTRG.10821","CX3CR1","ENST00000358309;ENST00000542107;ENST00000399220;ENST00000435290;ENST00000541347;ENST00000412814","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0004930(G-protein coupled receptor activity);GO:0007186(G-protein coupled receptor signaling pathway);GO:0007155(cell adhesion);GO:0005886(plasma membrane);GO:0004871(signal transducer activity);GO:0007165(signal transduction);GO:0006935(chemotaxis);GO:0070098(chemokine-mediated signaling pathway);GO:0005515(protein binding);GO:0016032(viral process);GO:0005887(integral component of plasma membrane);GO:0016495(C-X3-C chemokine receptor activity);GO:0009611(response to wounding);GO:0004950(chemokine receptor activity);GO:0006968(cellular defense response);GO:0019960(C-X3-C chemokine binding);GO:0004896(cytokine receptor activity);GO:0001774(microglial cell activation);GO:0002052(positive regulation of neuroblast proliferation);GO:0002282(microglial cell activation involved in immune response);GO:0002881(negative regulation of chronic inflammatory response to non-antigenic stimulus);GO:0007613(memory);GO:0016525(negative regulation of angiogenesis);GO:0019221(cytokine-mediated signaling pathway);GO:0021795(cerebral cortex cell migration);GO:0030336(negative regulation of cell migration);GO:0045766(positive regulation of angiogenesis);GO:0048246(macrophage chemotaxis);GO:0071222(cellular response to lipopolysaccharide);GO:0071560(cellular response to transforming growth factor beta stimulus);GO:1900272(negative regulation of long-term synaptic potentiation);GO:2001240(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand);GO:0032809(neuronal cell body membrane);GO:0043005(neuron projection);GO:0048471(perinuclear region of cytoplasm);GO:0048471(perinuclear region of cytoplasm)","04060(Cytokine-cytokine receptor interaction);04062(Chemokine signaling pathway);04062(Chemokine signaling pathway)","K04192","NA","C-X3-C motif chemokine receptor 1 [Source:HGNC Symbol;Acc:HGNC:2558]",{"v":0.980650850341997,"d":"0.98"},{"v":38.5724526158687,"d":"38.57"},{"v":0.0254236063262038,"d":"0.03"},{"v":-5.29768749932551,"d":"-5.30"},{"v":2.92016560685736e-12,"d":"0.00"},{"v":8.47797079810863e-09,"d":"0.00"},"down","yes"]
["MSTRG.8286","CARD8-AS1","ENST00000602172","NA","NA","NA","NA","CARD8 antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:51408]",{"v":0.410835,"d":"0.41"},{"v":15.56928,"d":"15.57"},{"v":0.0263875400789247,"d":"0.03"},{"v":-5.24399932495182,"d":"-5.24"},{"v":7.33363197519804e-12,"d":"0.00"},{"v":1.7033093625595e-08,"d":"0.00"},"down","yes"]
["MSTRG.9412","CXCR1","ENST00000295683","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0004930(G-protein coupled receptor activity);GO:0007186(G-protein coupled receptor signaling pathway);GO:0005886(plasma membrane);GO:0004871(signal transducer activity);GO:0007165(signal transduction);GO:0006935(chemotaxis);GO:0070098(chemokine-mediated signaling pathway);GO:0016494(C-X-C chemokine receptor activity);GO:0043312(neutrophil degranulation);GO:0019959(interleukin-8 binding);GO:0006954(inflammatory response);GO:0030667(secretory granule membrane);GO:0004950(chemokine receptor activity);GO:0002407(dendritic cell chemotaxis);GO:0031623(receptor internalization);GO:0007166(cell surface receptor signaling pathway);GO:0004918(interleukin-8 receptor activity);GO:0038112(interleukin-8-mediated signaling pathway)","04072(Phospholipase D signaling pathway);04060(Cytokine-cytokine receptor interaction);04144(Endocytosis);04062(Chemokine signaling pathway);05120(Epithelial cell signaling in Helicobacter pylori infection)","K04175","NA","C-X-C motif chemokine receptor 1 [Source:HGNC Symbol;Acc:HGNC:6026]",{"v":4.634412,"d":"4.63"},{"v":150.870682,"d":"150.87"},{"v":0.0307177772285804,"d":"0.03"},{"v":-5.0247823649046,"d":"-5.02"},{"v":1.45089734765043E-11,"d":"0.00"},{"v":2.8082118163774E-8,"d":"0.00"},"down","yes"]
["MSTRG.801","FAM212B","ENST00000357260;ENST00000444059;ENST00000527621;ENST00000527570","GO:0005634(nucleus);GO:0071901(negative regulation of protein serine/threonine kinase activity);GO:0019901(protein kinase binding);GO:0030291(protein serine/threonine kinase inhibitor activity);GO:0030291(protein serine/threonine kinase inhibitor activity)","NA","NA","NA","family with sequence similarity 212 member B [Source:HGNC Symbol;Acc:HGNC:28045]",{"v":0.677877673682569,"d":"0.68"},{"v":13.7037224998441,"d":"13.70"},{"v":0.049466681311613,"d":"0.05"},{"v":-4.33739907653009,"d":"-4.34"},{"v":1.42379348439724e-09,"d":"0.00"},{"v":2.36207339061502e-06,"d":"0.00"},"down","yes"]
["MSTRG.12848","USP8P1","MSTRG.12848.1","NA","NA","NA","NA",null,{"v":2.419763,"d":"2.42"},{"v":44.296997,"d":"44.30"},{"v":0.0546258925859015,"d":"0.05"},{"v":-4.19427124136318,"d":"-4.19"},{"v":7.66763576682437e-09,"d":"0.00"},{"v":1.10318607029286E-5,"d":"0.00"},"down","yes"]
["MSTRG.21","AL732372.2;AL627309.2","ENST00000601486;MSTRG.21.1;ENST00000641579;ENST00000616311;ENST00000493797;ENST00000445840;ENST00000419160;ENST00000455464;ENST00000601814;ENST00000641049;ENST00000440038;ENST00000642124;ENST00000608420;ENST00000431812;ENST00000641063;ENST00000455207;ENST00000641303;ENST00000616947;ENST00000642074","NA","NA","NA","NA",null,{"v":6.30733544154827,"d":"6.31"},{"v":0.251704736435843,"d":"0.25"},{"v":25.0584694227871,"d":"25.06"},{"v":4.64722639208542,"d":"4.65"},{"v":8.54962079792971e-09,"d":"0.00"},{"v":1.10318607029286E-5,"d":"0.00"},"up","yes"]
["MSTRG.8382","FPR1","ENST00000304748;ENST00000595042;ENST00000594900;ENST00000600815;MSTRG.8382.1","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0004930(G-protein coupled receptor activity);GO:0007186(G-protein coupled receptor signaling pathway);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0004871(signal transducer activity);GO:0007165(signal transduction);GO:0004982(N-formyl peptide receptor activity);GO:0006935(chemotaxis);GO:0060326(cell chemotaxis);GO:0005887(integral component of plasma membrane);GO:0006954(inflammatory response);GO:0043312(neutrophil degranulation);GO:0005622(intracellular);GO:0030667(secretory granule membrane);GO:0035577(azurophil granule membrane);GO:0101003(ficolin-1-rich granule membrane);GO:0007188(adenylate cyclase-modulating G-protein coupled receptor signaling pathway);GO:0004875(complement receptor activity);GO:0002430(complement receptor mediated signaling pathway);GO:0007204(positive regulation of cytosolic calcium ion concentration);GO:0050900(leukocyte migration);GO:0007263(nitric oxide mediated signal transduction);GO:0000187(activation of MAPK activity);GO:0005124(scavenger receptor binding);GO:0050786(RAGE receptor binding);GO:0007200(phospholipase C-activating G-protein coupled receptor signaling pathway);GO:0007200(phospholipase C-activating G-protein coupled receptor signaling pathway)","04015(Rap1 signaling pathway);04080(Neuroactive ligand-receptor interaction);05150(Staphylococcus aureus infection);05150(Staphylococcus aureus infection)","K04172","NA","formyl peptide receptor 1 [Source:HGNC Symbol;Acc:HGNC:3826]",{"v":17.9086099419593,"d":"17.91"},{"v":282.96478754122,"d":"282.96"},{"v":0.0632891820129758,"d":"0.06"},{"v":-3.98189726816233,"d":"-3.98"},{"v":1.17542031702393E-8,"d":"0.00"},{"v":1.36501561415989e-05,"d":"0.00"},"down","yes"]
["MSTRG.8049","RPSAP58","ENST00000484897","NA","NA","NA","NA","ribosomal protein SA pseudogene 58 [Source:HGNC Symbol;Acc:HGNC:36809]",{"v":3.475975,"d":"3.48"},{"v":52.241642,"d":"52.24"},{"v":0.0665364806106209,"d":"0.07"},{"v":-3.90971063163757,"d":"-3.91"},{"v":2.29497247704139e-08,"d":"0.00"},{"v":2.42286503417106e-05,"d":"0.00"},"down","yes"]
["MSTRG.2800","ENDOD1","ENST00000278505","GO:0003676(nucleic acid binding);GO:0016020(membrane);GO:0016787(hydrolase activity);GO:0046872(metal ion binding);GO:0090305(nucleic acid phosphodiester bond hydrolysis);GO:0005576(extracellular region);GO:0004519(endonuclease activity);GO:0004518(nuclease activity);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0002576(platelet degranulation)","NA","NA","NA","endonuclease domain containing 1 [Source:HGNC Symbol;Acc:HGNC:29129]",{"v":0.399185,"d":"0.40"},{"v":5.952888,"d":"5.95"},{"v":0.0670573677851826,"d":"0.07"},{"v":-3.89846033589734,"d":"-3.90"},{"v":2.79294399303827e-08,"d":"0.00"},{"v":2.70287154926279E-5,"d":"0.00"},"down","yes"]
["MSTRG.4412","FBXO34","ENST00000313833;ENST00000557647;ENST00000555280","GO:0005515(protein binding);GO:0005515(protein binding)","NA","NA","NA","F-box protein 34 [Source:HGNC Symbol;Acc:HGNC:20201]",{"v":0.324193656907815,"d":"0.32"},{"v":4.88255860682313,"d":"4.88"},{"v":0.0663983134692476,"d":"0.07"},{"v":-3.91270959248647,"d":"-3.91"},{"v":3.28677898471849e-08,"d":"0.00"},{"v":2.93610494996429e-05,"d":"0.00"},"down","yes"]
["MSTRG.837","FAM46C","ENST00000369448;MSTRG.837.2","GO:0005515(protein binding)","NA","NA","NA","family with sequence similarity 46 member C [Source:HGNC Symbol;Acc:HGNC:24712]",{"v":5.59040394848222,"d":"5.59"},{"v":0.276150749869905,"d":"0.28"},{"v":20.2440295784671,"d":"20.24"},{"v":4.33942458226387,"d":"4.34"},{"v":5.25235672874792e-08,"d":"0.00"},{"v":4.3568299064964e-05,"d":"0.00"},"up","yes"]
["MSTRG.15336","AL034397.3","ENST00000621933;MSTRG.15336.1;ENST00000618234","NA","NA","NA","NA",null,{"v":1.59426684715026,"d":"1.59"},{"v":21.405459507772,"d":"21.41"},{"v":0.0744794498137919,"d":"0.07"},{"v":-3.74701377415307,"d":"-3.75"},{"v":6.47609992570982e-08,"d":"0.00"},{"v":4.93196140461361e-05,"d":"0.00"},"down","yes"]
["MSTRG.3894","MRPL57","ENST00000309594","GO:0030529(intracellular ribonucleoprotein complex);GO:0005840(ribosome);GO:0005739(mitochondrion);GO:0003735(structural constituent of ribosome);GO:0032543(mitochondrial translation);GO:0006412(translation);GO:0005761(mitochondrial ribosome);GO:0005743(mitochondrial inner membrane);GO:0070125(mitochondrial translational elongation);GO:0070126(mitochondrial translational termination)","NA","NA","NA","mitochondrial ribosomal protein L57 [Source:HGNC Symbol;Acc:HGNC:14514]",{"v":0.554468,"d":"0.55"},{"v":7.602687,"d":"7.60"},{"v":0.0729305310083132,"d":"0.07"},{"v":-3.777333291364,"d":"-3.78"},{"v":7.06953492221997e-08,"d":"0.00"},{"v":4.93196140461361e-05,"d":"0.00"},"down","yes"]
["MSTRG.8762","SERTAD2","ENST00000313349;ENST00000476805","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0030308(negative regulation of cell growth);GO:0003713(transcription coactivator activity);GO:0045893(positive regulation of transcription, DNA-templated);GO:0045893(positive regulation of transcription, DNA-templated)","NA","NA","NA","SERTA domain containing 2 [Source:HGNC Symbol;Acc:HGNC:30784]",{"v":0.257710100255021,"d":"0.26"},{"v":3.47387565317182,"d":"3.47"},{"v":0.0741851827712137,"d":"0.07"},{"v":-3.75272512795786,"d":"-3.75"},{"v":7.21978333578157E-8,"d":"0.00"},{"v":4.93196140461361e-05,"d":"0.00"},"down","yes"]
["MSTRG.2544","NEAT1;NEAT1_1","MSTRG.2544.1;ENST00000501122;ENST00000499732;ENST00000620348;ENST00000601801;ENST00000612303;ENST00000616315","NA","NA","NA","NA","nuclear paraspeckle assembly transcript 1 (non-protein coding) [Source:HGNC Symbol;Acc:HGNC:30815];Nuclear enriched abundant transcript 1 conserved region 1 [Source:RFAM;Acc:RF01955]",{"v":4.31846901634303,"d":"4.32"},{"v":0.2327792895413,"d":"0.23"},{"v":18.5517750520363,"d":"18.55"},{"v":4.21348532681449,"d":"4.21"},{"v":9.2048638296621e-08,"d":"0.00"},{"v":5.93867131410366e-05,"d":"0.00"},"up","yes"]
["MSTRG.8383","FPR2","ENST00000598776;ENST00000598953;ENST00000340023;MSTRG.8383.1;ENST00000600722;MSTRG.8383.3;ENST00000599326;ENST00000600258","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0004930(G-protein coupled receptor activity);GO:0007186(G-protein coupled receptor signaling pathway);GO:0004982(N-formyl peptide receptor activity);GO:0005886(plasma membrane);GO:0004871(signal transducer activity);GO:0007165(signal transduction);GO:0006935(chemotaxis);GO:0060326(cell chemotaxis);GO:0005887(integral component of plasma membrane);GO:0043312(neutrophil degranulation);GO:0035579(specific granule membrane);GO:0070821(tertiary granule membrane);GO:0006954(inflammatory response);GO:0007155(cell adhesion);GO:1904646(cellular response to amyloid-beta);GO:0005622(intracellular);GO:0006928(movement of cell or subcellular component);GO:0101003(ficolin-1-rich granule membrane);GO:0007200(phospholipase C-activating G-protein coupled receptor signaling pathway);GO:0070374(positive regulation of ERK1 and ERK2 cascade);GO:0004875(complement receptor activity);GO:0002430(complement receptor mediated signaling pathway);GO:0007204(positive regulation of cytosolic calcium ion concentration);GO:0050900(leukocyte migration);GO:0001934(positive regulation of protein phosphorylation);GO:0005737(cytoplasm);GO:0005124(scavenger receptor binding);GO:0007194(negative regulation of adenylate cyclase activity);GO:0019722(calcium-mediated signaling);GO:0032930(positive regulation of superoxide anion generation);GO:0050918(positive chemotaxis);GO:0090026(positive regulation of monocyte chemotaxis);GO:0090026(positive regulation of monocyte chemotaxis)","04080(Neuroactive ligand-receptor interaction);05150(Staphylococcus aureus infection);05150(Staphylococcus aureus infection)","K04173","NA","formyl peptide receptor 2 [Source:HGNC Symbol;Acc:HGNC:3827]",{"v":29.5568899022439,"d":"29.56"},{"v":1.69114929415685,"d":"1.69"},{"v":17.4773983612014,"d":"17.48"},{"v":4.12741853998117,"d":"4.13"},{"v":1.47099359172185e-07,"d":"0.00"},{"v":8.99086767403463e-05,"d":"0.00"},"up","yes"]
["MSTRG.734","S1PR1","ENST00000305352;ENST00000475821;MSTRG.734.1;ENST00000475289","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0043231(intracellular membrane-bounded organelle);GO:0004930(G-protein coupled receptor activity);GO:0007186(G-protein coupled receptor signaling pathway);GO:0005654(nucleoplasm);GO:0005886(plasma membrane);GO:0004871(signal transducer activity);GO:0007165(signal transduction);GO:0038036(sphingosine-1-phosphate receptor activity);GO:0045121(membrane raft);GO:0006935(chemotaxis);GO:0005768(endosome);GO:0030500(regulation of bone mineralization);GO:0072678(T cell migration);GO:0007155(cell adhesion);GO:0031226(intrinsic component of plasma membrane);GO:0030032(lamellipodium assembly);GO:0001664(G-protein coupled receptor binding);GO:0016477(cell migration);GO:0001525(angiogenesis);GO:0031532(actin cytoskeleton reorganization);GO:0003376(sphingosine-1-phosphate signaling pathway);GO:0045124(regulation of bone resorption);GO:0001955(blood vessel maturation);GO:0046625(sphingolipid binding);GO:0003245(cardiac muscle tissue growth involved in heart morphogenesis);GO:0007193(adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway);GO:0007420(brain development);GO:0008284(positive regulation of cell proliferation);GO:0019226(transmission of nerve impulse);GO:0030155(regulation of cell adhesion);GO:0030182(neuron differentiation);GO:0030335(positive regulation of cell migration);GO:0030595(leukocyte chemotaxis);GO:0043547(positive regulation of GTPase activity);GO:0045446(endothelial cell differentiation);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0048661(positive regulation of smooth muscle cell proliferation);GO:0050927(positive regulation of positive chemotaxis);GO:0051482(positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway);GO:0051497(negative regulation of stress fiber assembly);GO:0061384(heart trabecula morphogenesis);GO:0009897(external side of plasma membrane);GO:0009897(external side of plasma membrane)","04068(FoxO signaling pathway);04071(Sphingolipid signaling pathway);04080(Neuroactive ligand-receptor interaction);04080(Neuroactive ligand-receptor interaction)","K04288","NA","sphingosine-1-phosphate receptor 1 [Source:HGNC Symbol;Acc:HGNC:3165]",{"v":18.5196427416174,"d":"18.52"},{"v":1.06421690084275,"d":"1.06"},{"v":17.4021317712129,"d":"17.40"},{"v":4.1211921427645,"d":"4.12"},{"v":1.5567755581487e-07,"d":"0.00"},{"v":9.0394172783904e-05,"d":"0.00"},"up","yes"]
["MSTRG.2203","GVINP1","MSTRG.2203.3;ENST00000526769","NA","NA","NA","NA","GTPase, very large interferon inducible pseudogene 1 [Source:HGNC Symbol;Acc:HGNC:25813]",{"v":0.0961619587083708,"d":"0.10"},{"v":1.18800759788479,"d":"1.19"},{"v":0.0809438920084216,"d":"0.08"},{"v":-3.62693397029229,"d":"-3.63"},{"v":2.08261839651901E-7,"d":"0.00"},{"v":1.15168797327501E-4,"d":"0.00"},"down","yes"]
["ENSG00000153879","CEBPG","ENST00000284000;ENST00000585933","GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0006355(regulation of transcription, DNA-templated);GO:0006366(transcription from RNA polymerase II promoter);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0005515(protein binding);GO:0006955(immune response);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0043565(sequence-specific DNA binding);GO:0008134(transcription factor binding);GO:0043433(negative regulation of sequence-specific DNA binding transcription factor activity);GO:0046982(protein heterodimerization activity);GO:0051091(positive regulation of sequence-specific DNA binding transcription factor activity);GO:0001077(transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0045078(positive regulation of interferon-gamma biosynthetic process);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0045739(positive regulation of DNA repair);GO:0001889(liver development);GO:0043388(positive regulation of DNA binding);GO:0030183(B cell differentiation);GO:0042267(natural killer cell mediated cytotoxicity);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:0003690(double-stranded DNA binding);GO:0042803(protein homodimerization activity);GO:0044377(RNA polymerase II core promoter proximal region sequence-specific DNA binding, bending);GO:0016071(mRNA metabolic process);GO:0043353(enucleate erythrocyte differentiation);GO:0043353(enucleate erythrocyte differentiation)","05152(Tuberculosis);05152(Tuberculosis)","K10049","NA","CCAAT/enhancer binding protein gamma [Source:HGNC Symbol;Acc:HGNC:1837]",{"v":4.92092040172297,"d":"4.92"},{"v":0.282420664021764,"d":"0.28"},{"v":17.4240805599967,"d":"17.42"},{"v":4.12301062435091,"d":"4.12"},{"v":2.44655570462849e-07,"d":"0.00"},{"v":0.000125540547704931,"d":"0.00"},"up","yes"]
["MSTRG.7833","ZNF627","ENST00000361113;ENST00000593279;ENST00000588651;ENST00000587939;ENST00000588174","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0005622(intracellular);GO:0005515(protein binding);GO:0005515(protein binding)","NA","NA","NA","zinc finger protein 627 [Source:HGNC Symbol;Acc:HGNC:30570]",{"v":0.225997936242488,"d":"0.23"},{"v":2.78163622158349,"d":"2.78"},{"v":0.0812464025629617,"d":"0.08"},{"v":-3.62155225513981,"d":"-3.62"},{"v":2.48637957221512e-07,"d":"0.00"},{"v":0.000125540547704931,"d":"0.00"},"down","yes"]
["MSTRG.1942","WBP1L","ENST00000448841;ENST00000369889","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005515(protein binding);GO:0005515(protein binding)","NA","NA","NA","WW domain binding protein 1 like [Source:HGNC Symbol;Acc:HGNC:23510]",{"v":20.707589373978,"d":"20.71"},{"v":1.26745798388227,"d":"1.27"},{"v":16.3378902001547,"d":"16.34"},{"v":4.03014978741033,"d":"4.03"},{"v":2.75265391830943e-07,"d":"0.00"},{"v":0.000133194041472198,"d":"0.00"},"up","yes"]
["MSTRG.325","MED18","ENST00000373842;ENST00000475655;ENST00000474683;ENST00000479574","GO:0005634(nucleus);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0001104(RNA polymerase II transcription cofactor activity);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0016592(mediator complex);GO:0005515(protein binding);GO:0070847(core mediator complex);GO:0006369(termination of RNA polymerase II transcription);GO:0061630(ubiquitin protein ligase activity);GO:0016567(protein ubiquitination);GO:0000151(ubiquitin ligase complex);GO:0000151(ubiquitin ligase complex)","NA","NA","NA","mediator complex subunit 18 [Source:HGNC Symbol;Acc:HGNC:25944]",{"v":0.488049550272412,"d":"0.49"},{"v":5.82585003268945,"d":"5.83"},{"v":0.0837731056470584,"d":"0.08"},{"v":-3.57736903149621,"d":"-3.58"},{"v":3.1544813766014E-7,"d":"0.00"},{"v":0.000146531968905888,"d":"0.00"},"down","yes"]
["MSTRG.3671","CKAP4","ENST00000378026;ENST00000553039;ENST00000552828","GO:0003723(RNA binding);GO:0005737(cytoplasm);GO:0016607(nuclear speck);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005829(cytosol);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005886(plasma membrane);GO:0005856(cytoskeleton);GO:0048471(perinuclear region of cytoplasm);GO:0000932(P-body);GO:0070062(extracellular exosome);GO:0044267(cellular protein metabolic process);GO:0043687(post-translational protein modification);GO:0031012(extracellular matrix);GO:0043312(neutrophil degranulation);GO:0035579(specific granule membrane);GO:0005788(endoplasmic reticulum lumen);GO:0035577(azurophil granule membrane);GO:0005811(lipid particle);GO:0005791(rough endoplasmic reticulum);GO:0042599(lamellar body);GO:0042599(lamellar body)","04141(Protein processing in endoplasmic reticulum);04141(Protein processing in endoplasmic reticulum)","K13999","NA","cytoskeleton associated protein 4 [Source:HGNC Symbol;Acc:HGNC:16991]",{"v":1.00233281445849,"d":"1.00"},{"v":10.7790029521715,"d":"10.78"},{"v":0.0929893811984311,"d":"0.09"},{"v":-3.42679021083402,"d":"-3.43"},{"v":4.36926775863044e-07,"d":"0.00"},{"v":0.000195155024926828,"d":"0.00"},"down","yes"]
["MSTRG.13739","YWHAG","ENST00000307630","GO:0005739(mitochondrion);GO:0003723(RNA binding);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0019904(protein domain specific binding);GO:0005515(protein binding);GO:0071901(negative regulation of protein serine/threonine kinase activity);GO:0005925(focal adhesion);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0061024(membrane organization);GO:0000086(G2/M transition of mitotic cell cycle);GO:0010389(regulation of G2/M transition of mitotic cell cycle);GO:0097711(ciliary basal body docking);GO:0005159(insulin-like growth factor receptor binding);GO:0009966(regulation of signal transduction);GO:0048167(regulation of synaptic plasticity);GO:0006469(negative regulation of protein kinase activity);GO:1900740(positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway);GO:0030659(cytoplasmic vesicle membrane);GO:0005080(protein kinase C binding);GO:0008426(protein kinase C inhibitor activity);GO:0030971(receptor tyrosine kinase binding);GO:0006605(protein targeting);GO:0032869(cellular response to insulin stimulus);GO:0045664(regulation of neuron differentiation);GO:0031982(vesicle);GO:0043209(myelin sheath)","04390(Hippo signaling pathway);04151(PI3K-Akt signaling pathway);04110(Cell cycle);04114(Oocyte meiosis);05203(Viral carcinogenesis);05169(Epstein-Barr virus infection)","K16198","NA","tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein gamma [Source:HGNC Symbol;Acc:HGNC:12852]",{"v":1.052171,"d":"1.05"},{"v":11.063588,"d":"11.06"},{"v":0.0951021495015903,"d":"0.10"},{"v":-3.39437824048448,"d":"-3.39"},{"v":5.21804044609233e-07,"d":"0.00"},{"v":2.24433717409149E-4,"d":"0.00"},"down","yes"]
["MSTRG.13990","TMEM140","ENST00000275767;ENST00000466307","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005515(protein binding);GO:0005515(protein binding)","NA","NA","NA","transmembrane protein 140 [Source:HGNC Symbol;Acc:HGNC:21870]",{"v":3.13505887246001,"d":"3.14"},{"v":31.8891639135322,"d":"31.89"},{"v":0.0983111028235408,"d":"0.10"},{"v":-3.34650183237543,"d":"-3.35"},{"v":6.48433476792596e-07,"d":"0.00"},{"v":0.000268937784499729,"d":"0.00"},"down","yes"]
["MSTRG.1209","KIAA0040","ENST00000423313;ENST00000545251;ENST00000567124;ENST00000444639;ENST00000619513;ENST00000563563","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005515(protein binding);GO:0005515(protein binding)","NA","NA","NA","KIAA0040 [Source:HGNC Symbol;Acc:HGNC:28950]",{"v":30.7813552906126,"d":"30.78"},{"v":2.16492702216182,"d":"2.16"},{"v":14.2181953366148,"d":"14.22"},{"v":3.82966645547474,"d":"3.83"},{"v":8.95197077751996e-07,"d":"0.00"},{"v":3.58480126342549E-4,"d":"0.00"},"up","yes"]
["MSTRG.11799","TIFA","ENST00000361717","GO:0005622(intracellular);GO:0005515(protein binding);GO:0007249(I-kappaB kinase/NF-kappaB signaling)","NA","NA","NA","TRAF interacting protein with forkhead associated domain [Source:HGNC Symbol;Acc:HGNC:19075]",{"v":0.395453942823529,"d":"0.40"},{"v":3.78986354117647,"d":"3.79"},{"v":0.104345166660214,"d":"0.10"},{"v":-3.26056431946709,"d":"-3.26"},{"v":1.42298282942077E-6,"d":"0.00"},{"v":0.000550836653268782,"d":"0.00"},"down","yes"]
["MSTRG.14381","VCPIP1","ENST00000310421","GO:0016787(hydrolase activity);GO:0016567(protein ubiquitination);GO:0005794(Golgi apparatus);GO:0005783(endoplasmic reticulum);GO:0008233(peptidase activity);GO:0008234(cysteine-type peptidase activity);GO:0006508(proteolysis);GO:0036459(thiol-dependent ubiquitinyl hydrolase activity);GO:0005737(cytoplasm);GO:0016579(protein deubiquitination);GO:0004843(thiol-dependent ubiquitin-specific protease activity);GO:0071108(protein K48-linked deubiquitination);GO:0005795(Golgi stack);GO:0005788(endoplasmic reticulum lumen);GO:0035871(protein K11-linked deubiquitination);GO:0000278(mitotic cell cycle);GO:0007030(Golgi organization);GO:0016320(endoplasmic reticulum membrane fusion);GO:0090168(Golgi reassembly)","NA","NA","NA","valosin containing protein interacting protein 1 [Source:HGNC Symbol;Acc:HGNC:30897]",{"v":0.406218,"d":"0.41"},{"v":3.691799,"d":"3.69"},{"v":0.110032534273941,"d":"0.11"},{"v":-3.18399793390244,"d":"-3.18"},{"v":1.77467924141585e-06,"d":"0.00"},{"v":6.64817742921365E-4,"d":"0.00"},"down","yes"]
["MSTRG.3386","MFSD5","ENST00000329548;ENST00000534842;ENST00000546655;ENST00000552097","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0015098(molybdate ion transmembrane transporter activity);GO:0015689(molybdate ion transport);GO:0006810(transport);GO:0006811(ion transport);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0005515(protein binding)","NA","NA","NA","major facilitator superfamily domain containing 5 [Source:HGNC Symbol;Acc:HGNC:28156]",{"v":0.463355494382022,"d":"0.46"},{"v":4.46271363580008,"d":"4.46"},{"v":0.103828193381033,"d":"0.10"},{"v":-3.26772985034228,"d":"-3.27"},{"v":1.9037483236528E-6,"d":"0.00"},{"v":0.000690882165080624,"d":"0.00"},"down","yes"]
["MSTRG.9507","ARL4C","ENST00000390645;ENST00000339728","GO:0006810(transport);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005525(GTP binding);GO:0007264(small GTPase mediated signal transduction);GO:0000166(nucleotide binding);GO:0005829(cytosol);GO:0005622(intracellular);GO:0005886(plasma membrane);GO:0042995(cell projection);GO:0005515(protein binding);GO:0030175(filopodium);GO:0043014(alpha-tubulin binding);GO:0005634(nucleus);GO:0003924(GTPase activity);GO:0032456(endocytic recycling);GO:0032456(endocytic recycling)","NA","NA","NA","ADP ribosylation factor like GTPase 4C [Source:HGNC Symbol;Acc:HGNC:698]",{"v":2.174232,"d":"2.17"},{"v":18.9151892571642,"d":"18.92"},{"v":0.114946351867799,"d":"0.11"},{"v":-3.12096741591917,"d":"-3.12"},{"v":2.37686820220263e-06,"d":"0.00"},{"v":0.000834886936814517,"d":"0.00"},"down","yes"]
["MSTRG.1473","IRF2BP2","ENST00000366609;ENST00000366610;ENST00000491430","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0005654(nucleoplasm);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated)","NA","NA","NA","interferon regulatory factor 2 binding protein 2 [Source:HGNC Symbol;Acc:HGNC:21729]",{"v":0.631209080016935,"d":"0.63"},{"v":5.57000947269263,"d":"5.57"},{"v":0.113322801893153,"d":"0.11"},{"v":-3.14148991714992,"d":"-3.14"},{"v":2.44434305103708e-06,"d":"0.00"},{"v":0.000834886936814517,"d":"0.00"},"down","yes"]
["MSTRG.13647","VOPP1","ENST00000285279;ENST00000453256;ENST00000418904;ENST00000428097;ENST00000625836;ENST00000455023;ENST00000414113;ENST00000462326;ENST00000433959;ENST00000454227;ENST00000481197;ENST00000428648;ENST00000453112;ENST00000452832","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0004871(signal transducer activity);GO:0030659(cytoplasmic vesicle membrane);GO:0031410(cytoplasmic vesicle);GO:0007165(signal transduction);GO:0031301(integral component of organelle membrane);GO:0005768(endosome);GO:0005768(endosome)","NA","NA","NA","vesicular, overexpressed in cancer, prosurvival protein 1 [Source:HGNC Symbol;Acc:HGNC:34518]",{"v":1.79347580667412,"d":"1.79"},{"v":15.5498916881059,"d":"15.55"},{"v":0.115336868104744,"d":"0.12"},{"v":-3.11607434226352,"d":"-3.12"},{"v":2.61930218345644e-06,"d":"0.00"},{"v":0.000869084464470847,"d":"0.00"},"down","yes"]
["MSTRG.590","TCEANC2","ENST00000234827;ENST00000371331;ENST00000498272","GO:0005634(nucleus);GO:0006351(transcription, DNA-templated);GO:0005515(protein binding);GO:0005515(protein binding)","NA","NA","NA","transcription elongation factor A N-terminal and central domain containing 2 [Source:HGNC Symbol;Acc:HGNC:26494]",{"v":1.13603110572831,"d":"1.14"},{"v":0.0898913279869067,"d":"0.09"},{"v":12.6378275988289,"d":"12.64"},{"v":3.65967658516244,"d":"3.66"},{"v":4.18539805541834e-06,"d":"0.00"},{"v":1.3501396560437E-3,"d":"0.00"},"up","yes"]
["MSTRG.14189","PPP1R3B","ENST00000310455;ENST00000519699","GO:0050790(regulation of catalytic activity);GO:0019888(protein phosphatase regulator activity);GO:0006470(protein dephosphorylation);GO:0005975(carbohydrate metabolic process);GO:0005977(glycogen metabolic process);GO:0004721(phosphoprotein phosphatase activity);GO:0019899(enzyme binding);GO:0005979(regulation of glycogen biosynthetic process);GO:0005981(regulation of glycogen catabolic process);GO:0000164(protein phosphatase type 1 complex);GO:0042587(glycogen granule);GO:0043231(intracellular membrane-bounded organelle);GO:0043231(intracellular membrane-bounded organelle)","04910(Insulin signaling pathway);04931(Insulin resistance);04931(Insulin resistance)","K07189","NA","protein phosphatase 1 regulatory subunit 3B [Source:HGNC Symbol;Acc:HGNC:14942]",{"v":1.24460169909972,"d":"1.24"},{"v":9.65986139473684,"d":"9.66"},{"v":0.128842604281863,"d":"0.13"},{"v":-2.9563183677178,"d":"-2.96"},{"v":6.28915516165478e-06,"d":"0.00"},{"v":0.00197394483492694,"d":"0.00"},"down","yes"]
["ENSG00000196470","SIAH1","ENST00000568007;ENST00000573005;ENST00000380006;ENST00000356721;ENST00000394725","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0016740(transferase activity);GO:0016567(protein ubiquitination);GO:0007275(multicellular organism development);GO:0005515(protein binding);GO:0007049(cell cycle);GO:0006511(ubiquitin-dependent protein catabolic process);GO:0006915(apoptotic process);GO:0030154(cell differentiation);GO:0007283(spermatogenesis);GO:0042802(identical protein binding);GO:0005829(cytosol);GO:0044267(cellular protein metabolic process);GO:0000209(protein polyubiquitination);GO:0043065(positive regulation of apoptotic process);GO:0042787(protein ubiquitination involved in ubiquitin-dependent protein catabolic process);GO:0008022(protein C-terminus binding);GO:0007399(nervous system development);GO:0004842(ubiquitin-protein transferase activity);GO:0043161(proteasome-mediated ubiquitin-dependent protein catabolic process);GO:0007411(axon guidance);GO:0009653(anatomical structure morphogenesis);GO:2001244(positive regulation of intrinsic apoptotic signaling pathway);GO:0051402(neuron apoptotic process);GO:0030163(protein catabolic process);GO:0030877(beta-catenin destruction complex);GO:0061630(ubiquitin protein ligase activity);GO:0031648(protein destabilization);GO:0005769(early endosome);GO:0005886(plasma membrane);GO:0005886(plasma membrane)","04120(Ubiquitin mediated proteolysis);04310(Wnt signaling pathway);04115(p53 signaling pathway);04115(p53 signaling pathway)","K04506","EC:2.3.2.27","siah E3 ubiquitin protein ligase 1 [Source:HGNC Symbol;Acc:HGNC:10857]",{"v":0.218029001040892,"d":"0.22"},{"v":1.64665365754647,"d":"1.65"},{"v":0.132407321990076,"d":"0.13"},{"v":-2.91694519096962,"d":"-2.92"},{"v":1.24044650319869E-5,"d":"0.00"},{"v":3.69024492649592E-3,"d":"0.00"},"down","yes"]
["ENSG00000173706","HEG1","ENST00000311127;ENST00000487661;ENST00000477536;ENST00000482699","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005509(calcium ion binding);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0007275(multicellular organism development);GO:0030054(cell junction);GO:0007507(heart development);GO:0007043(cell-cell junction assembly);GO:0001570(vasculogenesis);GO:0001701(in utero embryonic development);GO:0001885(endothelial cell development);GO:0001886(endothelial cell morphogenesis);GO:0001944(vasculature development);GO:0001945(lymph vessel development);GO:0003017(lymph circulation);GO:0003209(cardiac atrium morphogenesis);GO:0003222(ventricular trabecula myocardium morphogenesis);GO:0003281(ventricular septum development);GO:0009791(post-embryonic development);GO:0030324(lung development);GO:0035264(multicellular organism growth);GO:0045216(cell-cell junction organization);GO:0048845(venous blood vessel morphogenesis);GO:0050878(regulation of body fluid levels);GO:0055017(cardiac muscle tissue growth);GO:0060039(pericardium development);GO:0090271(positive regulation of fibroblast growth factor production);GO:0005911(cell-cell junction);GO:0009897(external side of plasma membrane);GO:0009986(cell surface);GO:0009986(cell surface)","NA","NA","NA","heart development protein with EGF like domains 1 [Source:HGNC Symbol;Acc:HGNC:29227]",{"v":2.67567300231738,"d":"2.68"},{"v":0.253435098740554,"d":"0.25"},{"v":10.5576260573778,"d":"10.56"},{"v":3.40021356781564,"d":"3.40"},{"v":1.268959458117E-5,"d":"0.00"},{"v":3.69024492649592E-3,"d":"0.00"},"up","yes"]
["ENSG00000164284","GRPEL2","ENST00000329271;ENST00000416916;ENST00000513661;ENST00000507562","GO:0005739(mitochondrion);GO:0006457(protein folding);GO:0050790(regulation of catalytic activity);GO:0042803(protein homodimerization activity);GO:0051087(chaperone binding);GO:0000774(adenyl-nucleotide exchange factor activity);GO:0005759(mitochondrial matrix);GO:0030150(protein import into mitochondrial matrix);GO:0051082(unfolded protein binding);GO:0001405(presequence translocase-associated import motor);GO:0005743(mitochondrial inner membrane);GO:0005743(mitochondrial inner membrane)","NA","NA","NA","GrpE like 2, mitochondrial [Source:HGNC Symbol;Acc:HGNC:21060]",{"v":3.14584919529305,"d":"3.15"},{"v":0.292948766463001,"d":"0.29"},{"v":10.7385644024904,"d":"10.74"},{"v":3.42472923273188,"d":"3.42"},{"v":1.27719816583579E-5,"d":"0.00"},{"v":3.69024492649592E-3,"d":"0.00"},"up","yes"]
["MSTRG.5479","HBA2","MSTRG.5479.1;MSTRG.5479.2","NA","NA","NA","NA",null,{"v":4541.33833221579,"d":"4541.34"},{"v":445.371362521053,"d":"445.37"},{"v":10.1967452655897,"d":"10.20"},{"v":3.35003682173962,"d":"3.35"},{"v":1.30285061557162E-5,"d":"0.00"},{"v":3.69024492649592E-3,"d":"0.00"},"up","yes"]
["MSTRG.10010","RUNX1","ENST00000437180;ENST00000300305;ENST00000455571;ENST00000416754;ENST00000399240;ENST00000344691;ENST00000399237;ENST00000482318;ENST00000479325;ENST00000358356;ENST00000469087","GO:0005634(nucleus);GO:0043231(intracellular membrane-bounded organelle);GO:0005524(ATP binding);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0006355(regulation of transcription, DNA-templated);GO:0006366(transcription from RNA polymerase II promoter);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0005515(protein binding);GO:0045893(positive regulation of transcription, DNA-templated);GO:0001047(core promoter binding);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:1902036(regulation of hematopoietic stem cell differentiation);GO:0001228(transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding);GO:2000810(regulation of bicellular tight junction assembly);GO:0030097(hemopoiesis);GO:0000977(RNA polymerase II regulatory region sequence-specific DNA binding);GO:0045766(positive regulation of angiogenesis);GO:0045652(regulation of megakaryocyte differentiation);GO:0030111(regulation of Wnt signaling pathway);GO:0033146(regulation of intracellular estrogen receptor signaling pathway);GO:0032743(positive regulation of interleukin-2 production);GO:0045616(regulation of keratinocyte differentiation);GO:0071425(hematopoietic stem cell proliferation);GO:0045589(regulation of regulatory T cell differentiation);GO:0045637(regulation of myeloid cell differentiation);GO:0001959(regulation of cytokine-mediated signaling pathway);GO:0000975(regulatory region DNA binding);GO:0050855(regulation of B cell receptor signaling pathway);GO:0048935(peripheral nervous system neuron development);GO:0001503(ossification);GO:0002062(chondrocyte differentiation);GO:0030854(positive regulation of granulocyte differentiation);GO:0030854(positive regulation of granulocyte differentiation)","04530(Tight junction);04659(Th17 cell differentiation);05200(Pathways in cancer);05202(Transcriptional misregulation in cancers);05221(Acute myeloid leukemia);05220(Chronic myeloid leukemia);05220(Chronic myeloid leukemia)","K08367","NA","runt related transcription factor 1 [Source:HGNC Symbol;Acc:HGNC:10471]",{"v":3.21378445087967,"d":"3.21"},{"v":0.313253527353281,"d":"0.31"},{"v":10.259371947168,"d":"10.26"},{"v":3.35887051038985,"d":"3.36"},{"v":1.39843428556256e-05,"d":"0.00"},{"v":3.86667079958047E-3,"d":"0.00"},"up","yes"]
["MSTRG.4134","RNASE6","ENST00000304677","GO:0003676(nucleic acid binding);GO:0016787(hydrolase activity);GO:0090305(nucleic acid phosphodiester bond hydrolysis);GO:0005576(extracellular region);GO:0004519(endonuclease activity);GO:0004518(nuclease activity);GO:0005615(extracellular space);GO:0031410(cytoplasmic vesicle);GO:0045087(innate immune response);GO:0051607(defense response to virus);GO:0070062(extracellular exosome);GO:0050829(defense response to Gram-negative bacterium);GO:0005622(intracellular);GO:0019731(antibacterial humoral response);GO:0050830(defense response to Gram-positive bacterium);GO:0061844(antimicrobial humoral immune response mediated by antimicrobial peptide);GO:0019730(antimicrobial humoral response);GO:0004540(ribonuclease activity);GO:0006401(RNA catabolic process);GO:0006952(defense response);GO:0090501(RNA phosphodiester bond hydrolysis)","NA","NA","NA","ribonuclease A family member k6 [Source:HGNC Symbol;Acc:HGNC:10048]",{"v":8.390823,"d":"8.39"},{"v":0.779531,"d":"0.78"},{"v":10.7639375470636,"d":"10.76"},{"v":3.42813402040948,"d":"3.43"},{"v":1.55581587910727e-05,"d":"0.00"},{"v":0.00420178832652855,"d":"0.00"},"up","yes"]
["ENSG00000196646","ZNF136","ENST00000343979;ENST00000418338;ENST00000464860;ENST00000439995;ENST00000425827;ENST00000476676","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0005622(intracellular);GO:0005515(protein binding);GO:0003714(transcription corepressor activity);GO:0006366(transcription from RNA polymerase II promoter);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0000122(negative regulation of transcription from RNA polymerase II promoter)","NA","NA","NA","zinc finger protein 136 [Source:HGNC Symbol;Acc:HGNC:12920]",{"v":0.198479887741935,"d":"0.20"},{"v":1.45361684442396,"d":"1.45"},{"v":0.136542093952268,"d":"0.14"},{"v":-2.87258231316106,"d":"-2.87"},{"v":1.64458668264658E-5,"d":"0.00"},{"v":0.0042897939780967,"d":"0.00"},"down","yes"]
["ENSG00000127334","DYRK2","ENST00000344096;ENST00000537632;ENST00000319833","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0004713(protein tyrosine kinase activity);GO:0018108(peptidyl-tyrosine phosphorylation);GO:0005515(protein binding);GO:0006974(cellular response to DNA damage stimulus);GO:0006915(apoptotic process);GO:0000287(magnesium ion binding);GO:0007224(smoothened signaling pathway);GO:1901796(regulation of signal transduction by p53 class mediator);GO:0000151(ubiquitin ligase complex);GO:0004712(protein serine/threonine/tyrosine kinase activity);GO:0042771(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator);GO:0030145(manganese ion binding);GO:0045725(positive regulation of glycogen biosynthetic process);GO:0051534(negative regulation of NFAT protein import into nucleus);GO:0030529(intracellular ribonucleoprotein complex);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016021(integral component of membrane)","NA","NA","NA","dual specificity tyrosine phosphorylation regulated kinase 2 [Source:HGNC Symbol;Acc:HGNC:3093]",{"v":0.40541019538656,"d":"0.41"},{"v":2.82476224899937,"d":"2.82"},{"v":0.143520112367039,"d":"0.14"},{"v":-2.80067516997946,"d":"-2.80"},{"v":1.66228131416819e-05,"d":"0.00"},{"v":0.0042897939780967,"d":"0.00"},"down","yes"]
["MSTRG.2975","GSEC","ENST00000626810;ENST00000629441","NA","NA","NA","NA","G-quadruplex forming sequence containing lncRNA [Source:HGNC Symbol;Acc:HGNC:48645]",{"v":0.268233526188558,"d":"0.27"},{"v":1.94774798307816,"d":"1.95"},{"v":0.137714698471745,"d":"0.14"},{"v":-2.86024554644852,"d":"-2.86"},{"v":1.76856239827021e-05,"d":"0.00"},{"v":0.00446485111545912,"d":"0.00"},"down","yes"]
["MSTRG.15434","C1GALT1C1","ENST00000304661;ENST00000371313","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005515(protein binding);GO:0070062(extracellular exosome);GO:0000139(Golgi membrane);GO:0016266(O-glycan processing);GO:0006493(protein O-linked glycosylation);GO:0016263(glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity);GO:0016267(O-glycan processing, core 1);GO:0030168(platelet activation);GO:0036344(platelet morphogenesis);GO:0036344(platelet morphogenesis)","00512(Mucin type O-glycan biosynthesis);00512(Mucin type O-glycan biosynthesis)","K09653","EC:2.4.1.-","C1GALT1 specific chaperone 1 [Source:HGNC Symbol;Acc:HGNC:24338]",{"v":5.04410006610644,"d":"5.04"},{"v":0.482276156302521,"d":"0.48"},{"v":10.4589455650849,"d":"10.46"},{"v":3.38666550625206,"d":"3.39"},{"v":1.89276270728867e-05,"d":"0.00"},{"v":0.00467673474888155,"d":"0.00"},"up","yes"]
["MSTRG.8053","PLEKHF1","ENST00000592810;ENST00000436066;ENST00000586888;ENST00000588833","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0005515(protein binding);GO:0006915(apoptotic process);GO:0048471(perinuclear region of cytoplasm);GO:0005764(lysosome);GO:0016050(vesicle organization);GO:0005765(lysosomal membrane);GO:0072659(protein localization to plasma membrane);GO:0005768(endosome);GO:0007032(endosome organization);GO:0010508(positive regulation of autophagy);GO:0032266(phosphatidylinositol-3-phosphate binding);GO:0010314(phosphatidylinositol-5-phosphate binding);GO:0070273(phosphatidylinositol-4-phosphate binding);GO:2001244(positive regulation of intrinsic apoptotic signaling pathway);GO:0010008(endosome membrane);GO:0010008(endosome membrane)","NA","NA","NA","pleckstrin homology and FYVE domain containing 1 [Source:HGNC Symbol;Acc:HGNC:20764]",{"v":4.7937445460649,"d":"4.79"},{"v":0.482303005221932,"d":"0.48"},{"v":9.93927985967878,"d":"9.94"},{"v":3.31314132658565,"d":"3.31"},{"v":2.57788848718977e-05,"d":"0.00"},{"v":0.00611520782705941,"d":"0.01"},"up","yes"]
["MSTRG.7957","MRPL34","ENST00000252602;ENST00000595444;ENST00000597996;ENST00000594999","GO:0005622(intracellular);GO:0003735(structural constituent of ribosome);GO:0006412(translation);GO:0005840(ribosome);GO:0030529(intracellular ribonucleoprotein complex);GO:0005739(mitochondrion);GO:0005743(mitochondrial inner membrane);GO:0070125(mitochondrial translational elongation);GO:0070126(mitochondrial translational termination);GO:0005761(mitochondrial ribosome);GO:0005762(mitochondrial large ribosomal subunit);GO:0005762(mitochondrial large ribosomal subunit)","03010(Ribosome);03010(Ribosome)","K02914","NA","mitochondrial ribosomal protein L34 [Source:HGNC Symbol;Acc:HGNC:14488]",{"v":1.30999888552788,"d":"1.31"},{"v":8.81742080308422,"d":"8.82"},{"v":0.148569396287592,"d":"0.15"},{"v":-2.75079112821148,"d":"-2.75"},{"v":2.60135594649249e-05,"d":"0.00"},{"v":0.00611520782705941,"d":"0.01"},"down","yes"]
["ENSG00000161980","POLR3K","ENST00000293860;ENST00000481810","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0006351(transcription, DNA-templated);GO:0006379(mRNA cleavage);GO:0002376(immune system process);GO:0045087(innate immune response);GO:0005730(nucleolus);GO:0051607(defense response to virus);GO:0003899(DNA-directed 5'-3' RNA polymerase activity);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0001056(RNA polymerase III activity);GO:0032481(positive regulation of type I interferon production);GO:0005666(DNA-directed RNA polymerase III complex);GO:0006383(transcription from RNA polymerase III promoter);GO:0006386(termination of RNA polymerase III transcription);GO:0006386(termination of RNA polymerase III transcription)","00230(Purine metabolism);00240(Pyrimidine metabolism);03020(RNA polymerase);04623(Cytosolic DNA-sensing pathway);05169(Epstein-Barr virus infection);05169(Epstein-Barr virus infection)","K03019","NA","RNA polymerase III subunit K [Source:HGNC Symbol;Acc:HGNC:14121]",{"v":0.558086623610376,"d":"0.56"},{"v":3.79992262996294,"d":"3.80"},{"v":0.146867891259096,"d":"0.15"},{"v":-2.76740907125021,"d":"-2.77"},{"v":2.63291476236089e-05,"d":"0.00"},{"v":0.00611520782705941,"d":"0.01"},"down","yes"]
["MSTRG.8072","FFAR2","MSTRG.8072.2;ENST00000601590","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0004930(G-protein coupled receptor activity);GO:0007186(G-protein coupled receptor signaling pathway);GO:0005886(plasma membrane);GO:0004871(signal transducer activity);GO:0007165(signal transduction);GO:0002376(immune system process);GO:0006954(inflammatory response);GO:0008289(lipid binding);GO:0005515(protein binding);GO:0045444(fat cell differentiation);GO:0005887(integral component of plasma membrane);GO:0002232(leukocyte chemotaxis involved in inflammatory response);GO:0002385(mucosal immune response);GO:0002673(regulation of acute inflammatory response);GO:0002720(positive regulation of cytokine production involved in immune response);GO:0002879(positive regulation of acute inflammatory response to non-antigenic stimulus);GO:0019915(lipid storage);GO:0032722(positive regulation of chemokine production);GO:0042593(glucose homeostasis);GO:0071398(cellular response to fatty acid);GO:0090276(regulation of peptide hormone secretion);GO:0042995(cell projection);GO:2000484(positive regulation of interleukin-8 secretion);GO:0002752(cell surface pattern recognition receptor signaling pathway)","04024(cAMP signaling pathway)","NA","NA","free fatty acid receptor 2 [Source:HGNC Symbol;Acc:HGNC:4501]",{"v":21.1027822171767,"d":"21.10"},{"v":2.25333818854886,"d":"2.25"},{"v":9.36511985835859,"d":"9.37"},{"v":3.2272974587452,"d":"3.23"},{"v":2.72172321254503e-05,"d":"0.00"},{"v":0.00619752385633048,"d":"0.01"},"up","yes"]
["MSTRG.12023",null,"MSTRG.12023.1","NA","NA","NA","NA",null,{"v":7.775853,"d":"7.78"},{"v":0.821722,"d":"0.82"},{"v":9.46287552237862,"d":"9.46"},{"v":3.2422786477825,"d":"3.24"},{"v":2.90114695834432e-05,"d":"0.00"},{"v":0.0064790422360101,"d":"0.01"},"up","yes"]
["MSTRG.11839","MAML3","ENST00000509479;ENST00000398940","GO:0005634(nucleus);GO:0016607(nuclear speck);GO:0003713(transcription coactivator activity);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0007219(Notch signaling pathway);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0005654(nucleoplasm);GO:0006367(transcription initiation from RNA polymerase II promoter);GO:0007221(positive regulation of transcription of Notch receptor target);GO:0007221(positive regulation of transcription of Notch receptor target)","04330(Notch signaling pathway);04658(Th1 and Th2 cell differentiation);05165(Human papillomavirus infection);05165(Human papillomavirus infection)","K06061","NA","mastermind like transcriptional coactivator 3 [Source:HGNC Symbol;Acc:HGNC:16272]",{"v":3.49721310330579,"d":"3.50"},{"v":0.37220905785124,"d":"0.37"},{"v":9.39583019149285,"d":"9.40"},{"v":3.2320206401163,"d":"3.23"},{"v":3.06689300309122e-05,"d":"0.00"},{"v":0.00665142220381148,"d":"0.01"},"up","yes"]
["ENSG00000071246","VASH1","ENST00000167106;ENST00000556038;ENST00000554237;ENST00000553518","GO:0005737(cytoplasm);GO:0005783(endoplasmic reticulum);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0007049(cell cycle);GO:0005615(extracellular space);GO:0045765(regulation of angiogenesis);GO:0016525(negative regulation of angiogenesis);GO:0007050(cell cycle arrest);GO:0001937(negative regulation of endothelial cell proliferation);GO:0009611(response to wounding);GO:0043537(negative regulation of blood vessel endothelial cell migration);GO:0001525(angiogenesis);GO:0010596(negative regulation of endothelial cell migration);GO:0045177(apical part of cell);GO:0060674(placenta blood vessel development);GO:0060716(labyrinthine layer blood vessel development);GO:1901491(negative regulation of lymphangiogenesis);GO:2000772(regulation of cellular senescence);GO:2000772(regulation of cellular senescence)","NA","NA","NA","vasohibin 1 [Source:HGNC Symbol;Acc:HGNC:19964]",{"v":2.67407082620732,"d":"2.67"},{"v":0.281860178099046,"d":"0.28"},{"v":9.48722463826603,"d":"9.49"},{"v":3.24598610766664,"d":"3.25"},{"v":3.09288555072608e-05,"d":"0.00"},{"v":0.00665142220381148,"d":"0.01"},"up","yes"]
["ENSG00000127311","HELB","ENST00000247815;ENST00000440906;ENST00000545134;ENST00000545455;ENST00000542394","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0016787(hydrolase activity);GO:0004003(ATP-dependent DNA helicase activity);GO:0004386(helicase activity);GO:0032508(DNA duplex unwinding);GO:0005694(chromosome);GO:0006281(DNA repair);GO:0006974(cellular response to DNA damage stimulus);GO:0006260(DNA replication);GO:0006261(DNA-dependent DNA replication);GO:0006269(DNA replication, synthesis of RNA primer);GO:0003723(RNA binding);GO:0004004(ATP-dependent RNA helicase activity);GO:0035861(site of double-strand break);GO:0005662(DNA replication factor A complex);GO:2000042(negative regulation of double-strand break repair via homologous recombination);GO:0005658(alpha DNA polymerase:primase complex);GO:0043141(ATP-dependent 5'-3' DNA helicase activity);GO:0006396(RNA processing);GO:0017116(single-stranded DNA-dependent ATP-dependent DNA helicase activity);GO:1903775(regulation of DNA double-strand break processing);GO:1903775(regulation of DNA double-strand break processing)","NA","NA","NA","DNA helicase B [Source:HGNC Symbol;Acc:HGNC:17196]",{"v":2.12863736981734,"d":"2.13"},{"v":0.230810648738765,"d":"0.23"},{"v":9.22244004533155,"d":"9.22"},{"v":3.20514850505493,"d":"3.21"},{"v":3.43981710590525e-05,"d":"0.00"},{"v":0.00726301746379594,"d":"0.01"},"up","yes"]
["ENSG00000116983","HPCAL4","ENST00000372844;ENST00000617690","GO:0046872(metal ion binding);GO:0005509(calcium ion binding);GO:0007165(signal transduction);GO:0005515(protein binding);GO:0065009(regulation of molecular function);GO:0005246(calcium channel regulator activity);GO:0007417(central nervous system development);GO:0005622(intracellular);GO:0008022(protein C-terminus binding);GO:0019904(protein domain specific binding);GO:0019904(protein domain specific binding)","NA","NA","NA","hippocalcin like 4 [Source:HGNC Symbol;Acc:HGNC:18212]",{"v":0.224386122531237,"d":"0.22"},{"v":1.47285063603386,"d":"1.47"},{"v":0.152348185920245,"d":"0.15"},{"v":-2.71455577359253,"d":"-2.71"},{"v":3.70891332079463e-05,"d":"0.00"},{"v":0.00759007749164194,"d":"0.01"},"down","yes"]
["ENSG00000183808","RBM12B","ENST00000399300;ENST00000520961;ENST00000519109;ENST00000518597;ENST00000521947;ENST00000520560","GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0005515(protein binding);GO:0005515(protein binding)","NA","NA","NA","RNA binding motif protein 12B [Source:HGNC Symbol;Acc:HGNC:32310]",{"v":1.79973878590181,"d":"1.80"},{"v":0.190655222630612,"d":"0.19"},{"v":9.43975602173114,"d":"9.44"},{"v":3.23874957242745,"d":"3.24"},{"v":3.76481013440679e-05,"d":"0.00"},{"v":0.00759007749164194,"d":"0.01"},"up","yes"]
["MSTRG.5916","HNRNPA1P48","ENST00000562726;ENST00000565308","NA","NA","NA","NA","heterogeneous nuclear ribonucleoprotein A1 pseudogene 48 [Source:HGNC Symbol;Acc:HGNC:48778]",{"v":3.70626222149601,"d":"3.71"},{"v":23.117348,"d":"23.12"},{"v":0.160323849495886,"d":"0.16"},{"v":-2.64093904063563,"d":"-2.64"},{"v":3.79079044618301e-05,"d":"0.00"},{"v":0.00759007749164194,"d":"0.01"},"down","yes"]
["MSTRG.2324","TRIM44","ENST00000299413","GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0005622(intracellular);GO:0005515(protein binding);GO:0010468(regulation of gene expression)","NA","NA","NA","tripartite motif containing 44 [Source:HGNC Symbol;Acc:HGNC:19016]",{"v":0.494421402768219,"d":"0.49"},{"v":3.04679180515409,"d":"3.05"},{"v":0.162276070826971,"d":"0.16"},{"v":-2.62347781862732,"d":"-2.62"},{"v":4.05536008248064E-5,"d":"0.00"},{"v":0.00798218587082165,"d":"0.01"},"down","yes"]
["MSTRG.12176","TMEM167A","ENST00000502346;ENST00000503892;ENST00000509770;ENST00000511450;ENST00000504622","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005794(Golgi apparatus);GO:0000139(Golgi membrane);GO:0012505(endomembrane system);GO:0009306(protein secretion);GO:0046907(intracellular transport);GO:0046907(intracellular transport)","NA","NA","NA","transmembrane protein 167A [Source:HGNC Symbol;Acc:HGNC:28330]",{"v":12.6207126230644,"d":"12.62"},{"v":1.42662267196414,"d":"1.43"},{"v":8.8465666998608,"d":"8.85"},{"v":3.14511766241426,"d":"3.15"},{"v":4.44281836906475E-5,"d":"0.00"},{"v":0.00859907495332482,"d":"0.01"},"up","yes"]
["MSTRG.211","MUL1","ENST00000264198","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0046872(metal ion binding);GO:0016740(transferase activity);GO:0016567(protein ubiquitination);GO:0004842(ubiquitin-protein transferase activity);GO:0005739(mitochondrion);GO:0005515(protein binding);GO:0004871(signal transducer activity);GO:0006915(apoptotic process);GO:0005741(mitochondrial outer membrane);GO:0006996(organelle organization);GO:0031647(regulation of protein stability);GO:0051881(regulation of mitochondrial membrane potential);GO:1903861(positive regulation of dendrite extension);GO:1904925(positive regulation of mitophagy in response to mitochondrial depolarization);GO:0005777(peroxisome);GO:0050821(protein stabilization);GO:0042802(identical protein binding);GO:0045824(negative regulation of innate immune response);GO:0031625(ubiquitin protein ligase binding);GO:0016925(protein sumoylation);GO:0043123(positive regulation of I-kappaB kinase/NF-kappaB signaling);GO:0030308(negative regulation of cell growth);GO:0000266(mitochondrial fission);GO:0006919(activation of cysteine-type endopeptidase activity involved in apoptotic process);GO:0051898(negative regulation of protein kinase B signaling);GO:0010821(regulation of mitochondrion organization);GO:0031648(protein destabilization);GO:0043025(neuronal cell body);GO:0033235(positive regulation of protein sumoylation);GO:0071360(cellular response to exogenous dsRNA);GO:0051646(mitochondrion localization);GO:0030424(axon);GO:0060339(negative regulation of type I interferon-mediated signaling pathway);GO:0007257(activation of JUN kinase activity);GO:0031307(integral component of mitochondrial outer membrane);GO:0050689(negative regulation of defense response to virus by host);GO:0019789(SUMO transferase activity);GO:1901028(regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway);GO:0010637(negative regulation of mitochondrial fusion);GO:0071650(negative regulation of chemokine (C-C motif) ligand 5 production);GO:0090141(positive regulation of mitochondrial fission)","NA","NA","NA","mitochondrial E3 ubiquitin protein ligase 1 [Source:HGNC Symbol;Acc:HGNC:25762]",{"v":1.089991,"d":"1.09"},{"v":6.686655,"d":"6.69"},{"v":0.163009905550683,"d":"0.16"},{"v":-2.61696846015714,"d":"-2.62"},{"v":4.75789113805449e-05,"d":"0.00"},{"v":0.00905793275184045,"d":"0.01"},"down","yes"]
["MSTRG.11520","LINC002481","ENST00000499502","NA","NA","NA","NA","long intergenic non-protein coding RNA 2481 [Source:HGNC Symbol;Acc:HGNC:27958]",{"v":0.542813,"d":"0.54"},{"v":3.45952,"d":"3.46"},{"v":0.156904136990103,"d":"0.16"},{"v":-2.67204470347095,"d":"-2.67"},{"v":4.8727565482844e-05,"d":"0.00"},{"v":0.00912698738632689,"d":"0.01"},"down","yes"]
["MSTRG.9621","CD93","ENST00000246006","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0030246(carbohydrate binding);GO:0005509(calcium ion binding);GO:0007155(cell adhesion);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0004872(receptor activity);GO:0016032(viral process);GO:0031012(extracellular matrix);GO:0043312(neutrophil degranulation);GO:0035579(specific granule membrane);GO:0070821(tertiary granule membrane);GO:0042116(macrophage activation);GO:0030667(secretory granule membrane);GO:0006909(phagocytosis);GO:0016337(single organismal cell-cell adhesion);GO:0101003(ficolin-1-rich granule membrane);GO:0001849(complement component C1q binding);GO:0009986(cell surface);GO:0031410(cytoplasmic vesicle)","NA","NA","NA","CD93 molecule [Source:HGNC Symbol;Acc:HGNC:15855]",{"v":2.282617,"d":"2.28"},{"v":13.392887,"d":"13.39"},{"v":0.170435022710189,"d":"0.17"},{"v":-2.55270626930868,"d":"-2.55"},{"v":5.52987112841267e-05,"d":"0.00"},{"v":0.0101933957800407,"d":"0.01"},"down","yes"]
["MSTRG.12132","AC113404.3","MSTRG.12132.1;ENST00000506621","NA","NA","NA","NA",null,{"v":13.209632,"d":"13.21"},{"v":1.524998,"d":"1.52"},{"v":8.66206513057722,"d":"8.66"},{"v":3.11471102015514,"d":"3.11"},{"v":6.39949656433494e-05,"d":"0.00"},{"v":0.0116120865002534,"d":"0.01"},"up","yes"]
["MSTRG.9855","TUBB1","ENST00000217133","GO:0005737(cytoplasm);GO:0005525(GTP binding);GO:0000166(nucleotide binding);GO:0003924(GTPase activity);GO:0015630(microtubule cytoskeleton);GO:0005856(cytoskeleton);GO:0005200(structural constituent of cytoskeleton);GO:0005874(microtubule);GO:0007017(microtubule-based process);GO:0070062(extracellular exosome);GO:0051225(spindle assembly)","04145(Phagosome);04540(Gap junction);05130(Pathogenic Escherichia coli infection)","K07375","NA","tubulin beta 1 class VI [Source:HGNC Symbol;Acc:HGNC:16257]",{"v":15.550496,"d":"15.55"},{"v":88.920532,"d":"88.92"},{"v":0.174880825049495,"d":"0.17"},{"v":-2.51555598242909,"d":"-2.52"},{"v":6.64181533443009e-05,"d":"0.00"},{"v":0.0118663694582672,"d":"0.01"},"down","yes"]
["MSTRG.8860","TGOLN2","ENST00000398263;ENST00000444342;ENST00000282120;ENST00000377386;ENST00000409015","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005794(Golgi apparatus);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0005802(trans-Golgi network);GO:0044267(cellular protein metabolic process);GO:0061024(membrane organization);GO:0005768(endosome);GO:0043687(post-translational protein modification);GO:0006895(Golgi to endosome transport);GO:0005788(endoplasmic reticulum lumen);GO:0030133(transport vesicle);GO:0030140(trans-Golgi network transport vesicle);GO:0030665(clathrin-coated vesicle membrane);GO:0030665(clathrin-coated vesicle membrane)","NA","NA","NA","trans-golgi network protein 2 [Source:HGNC Symbol;Acc:HGNC:15450]",{"v":37.1967325884762,"d":"37.20"},{"v":4.50865866854964,"d":"4.51"},{"v":8.25006622212139,"d":"8.25"},{"v":3.04440569971514,"d":"3.04"},{"v":7.05027506120907e-05,"d":"0.00"},{"v":0.0124052794372456,"d":"0.01"},"up","yes"]
["MSTRG.13950","AC090114.3;AC018638.8;AC108010.1","ENST00000479267;ENST00000588755;ENST00000605862","NA","NA","NA","NA",null,{"v":4.72291195417237,"d":"4.72"},{"v":0.528696086183311,"d":"0.53"},{"v":8.93313205374255,"d":"8.93"},{"v":3.15916608869192,"d":"3.16"},{"v":7.19738616595295e-05,"d":"0.00"},{"v":0.0124751112754047,"d":"0.01"},"up","yes"]
["MSTRG.8872","VAMP8","ENST00000263864;ENST00000432071;ENST00000409760","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016192(vesicle-mediated transport);GO:0006810(transport);GO:0005737(cytoplasm);GO:0015031(protein transport);GO:0005765(lysosomal membrane);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0048471(perinuclear region of cytoplasm);GO:0065009(regulation of molecular function);GO:0006914(autophagy);GO:0005764(lysosome);GO:0006906(vesicle fusion);GO:0005768(endosome);GO:0031902(late endosome membrane);GO:0070062(extracellular exosome);GO:0061024(membrane organization);GO:0002479(antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent);GO:0031901(early endosome membrane);GO:0055037(recycling endosome);GO:0043312(neutrophil degranulation);GO:0035579(specific granule membrane);GO:0070821(tertiary granule membrane);GO:0000149(SNARE binding);GO:0005484(SNAP receptor activity);GO:0006892(post-Golgi vesicle-mediated transport);GO:0030670(phagocytic vesicle membrane);GO:0031201(SNARE complex);GO:0030667(secretory granule membrane);GO:0031982(vesicle);GO:0035577(azurophil granule membrane);GO:0019869(chloride channel inhibitor activity);GO:1903076(regulation of protein localization to plasma membrane);GO:0030665(clathrin-coated vesicle membrane);GO:0008021(synaptic vesicle);GO:1903595(positive regulation of histamine secretion by mast cell);GO:0016240(autophagosome docking);GO:0097352(autophagosome maturation);GO:0070254(mucus secretion);GO:0055038(recycling endosome membrane);GO:0005769(early endosome);GO:1903531(negative regulation of secretion by cell);GO:0046718(viral entry into host cell);GO:0098594(mucin granule);GO:0098594(mucin granule)","04130(SNARE interactions in vesicular transport);04140(Autophagy - animal);04611(Platelet activation);04611(Platelet activation)","K08512","NA","vesicle associated membrane protein 8 [Source:HGNC Symbol;Acc:HGNC:12647]",{"v":10.9431048606061,"d":"10.94"},{"v":61.9936035636364,"d":"61.99"},{"v":0.176519902563383,"d":"0.18"},{"v":-2.5020972388089,"d":"-2.50"},{"v":7.46688697770243E-5,"d":"0.00"},{"v":0.0127519056576556,"d":"0.01"},"down","yes"]
["ENSG00000131115","ZNF227","ENST00000313040;ENST00000391961;ENST00000621083;ENST00000588219;ENST00000591019;ENST00000589707;ENST00000588394;ENST00000586048;ENST00000586228;ENST00000589005;ENST00000590871;ENST00000589237","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0005622(intracellular);GO:0005515(protein binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding)","NA","NA","NA","zinc finger protein 227 [Source:HGNC Symbol;Acc:HGNC:13020]",{"v":1.8259692805287,"d":"1.83"},{"v":0.205589813769974,"d":"0.21"},{"v":8.88161357338308,"d":"8.88"},{"v":3.15082180302179,"d":"3.15"},{"v":7.91678762687235e-05,"d":"0.00"},{"v":0.0133242977841839,"d":"0.01"},"up","yes"]
["MSTRG.628","SLC35D1","ENST00000235345","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0008643(carbohydrate transport);GO:0006065(UDP-glucuronate biosynthetic process);GO:0015165(pyrimidine nucleotide-sugar transmembrane transporter activity);GO:0090481(pyrimidine nucleotide-sugar transmembrane transport);GO:0005461(UDP-glucuronic acid transmembrane transporter activity);GO:0015787(UDP-glucuronic acid transport)","NA","NA","NA","solute carrier family 35 member D1 [Source:HGNC Symbol;Acc:HGNC:20800]",{"v":2.496361,"d":"2.50"},{"v":0.303109,"d":"0.30"},{"v":8.23585244911896,"d":"8.24"},{"v":3.0419179833418,"d":"3.04"},{"v":8.86720695745389E-5,"d":"0.00"},{"v":0.014710696342416,"d":"0.01"},"up","yes"]
["MSTRG.8261","C5AR1","MSTRG.8261.7;ENST00000594787;MSTRG.8261.9;ENST00000595501;MSTRG.8261.3;MSTRG.8261.8;ENST00000355085;MSTRG.8261.6;MSTRG.8261.4;MSTRG.8261.5","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0004930(G-protein coupled receptor activity);GO:0007186(G-protein coupled receptor signaling pathway);GO:0005886(plasma membrane);GO:0004871(signal transducer activity);GO:0007165(signal transduction);GO:0006935(chemotaxis);GO:0031410(cytoplasmic vesicle);GO:0030449(regulation of complement activation);GO:0060326(cell chemotaxis);GO:0006954(inflammatory response);GO:0016323(basolateral plasma membrane);GO:0004875(complement receptor activity);GO:0005887(integral component of plasma membrane);GO:0043312(neutrophil degranulation);GO:0006955(immune response);GO:0070374(positive regulation of ERK1 and ERK2 cascade);GO:0030667(secretory granule membrane);GO:0050679(positive regulation of epithelial cell proliferation);GO:0007200(phospholipase C-activating G-protein coupled receptor signaling pathway);GO:0007204(positive regulation of cytosolic calcium ion concentration);GO:0006968(cellular defense response);GO:0045177(apical part of cell);GO:0050900(leukocyte migration);GO:0000187(activation of MAPK activity);GO:0007202(activation of phospholipase C activity);GO:0042789(mRNA transcription from RNA polymerase II promoter);GO:0001856(complement component C5a binding);GO:0004878(complement component C5a receptor activity);GO:0002430(complement receptor mediated signaling pathway);GO:0006915(apoptotic process);GO:0007606(sensory perception of chemical stimulus);GO:0010575(positive regulation of vascular endothelial growth factor production);GO:0010759(positive regulation of macrophage chemotaxis);GO:0021534(cell proliferation in hindbrain);GO:0030593(neutrophil chemotaxis);GO:0031100(animal organ regeneration);GO:0032494(response to peptidoglycan);GO:0032496(response to lipopolysaccharide);GO:0038178(complement component C5a signaling pathway);GO:0043524(negative regulation of neuron apoptotic process);GO:0045766(positive regulation of angiogenesis);GO:0050830(defense response to Gram-positive bacterium);GO:0090023(positive regulation of neutrophil chemotaxis);GO:0009986(cell surface);GO:0009986(cell surface)","04080(Neuroactive ligand-receptor interaction);04610(Complement and coagulation cascades);05150(Staphylococcus aureus infection);05150(Staphylococcus aureus infection)","K04010","NA","complement C5a receptor 1 [Source:HGNC Symbol;Acc:HGNC:1338]",{"v":99.8297793726724,"d":"99.83"},{"v":12.5474226003147,"d":"12.55"},{"v":7.95619806175721,"d":"7.96"},{"v":2.99207919109853,"d":"2.99"},{"v":9.30651926605322e-05,"d":"0.00"},{"v":0.0152220574981234,"d":"0.02"},"up","yes"]
["ENSG00000171466","ZNF562","ENST00000587392;ENST00000585350;ENST00000453372;ENST00000588653;ENST00000293648;ENST00000590155","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0005622(intracellular);GO:0005622(intracellular)","NA","NA","NA","zinc finger protein 562 [Source:HGNC Symbol;Acc:HGNC:25950]",{"v":0.0863245567002383,"d":"0.09"},{"v":0.503976602906127,"d":"0.50"},{"v":0.171286833957086,"d":"0.17"},{"v":-2.54551383263541,"d":"-2.55"},{"v":0.000102308360800455,"d":"0.00"},{"v":0.0164168859425314,"d":"0.02"},"down","yes"]
["ENSG00000110400","NECTIN1","ENST00000264025;ENST00000340882;ENST00000532197;ENST00000341398;ENST00000524429;ENST00000524510","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0007155(cell adhesion);GO:0046982(protein heterodimerization activity);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0042803(protein homodimerization activity);GO:0005576(extracellular region);GO:0006955(immune response);GO:0030054(cell junction);GO:0045202(synapse);GO:0007165(signal transduction);GO:0005912(adherens junction);GO:0005887(integral component of plasma membrane);GO:0016032(viral process);GO:0050839(cell adhesion molecule binding);GO:0046718(viral entry into host cell);GO:0005913(cell-cell adherens junction);GO:0042734(presynaptic membrane);GO:0015026(coreceptor activity);GO:0005102(receptor binding);GO:0007156(homophilic cell adhesion via plasma membrane adhesion molecules);GO:0007157(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules);GO:0001618(virus receptor activity);GO:0016337(single organismal cell-cell adhesion);GO:0034332(adherens junction organization);GO:0008037(cell recognition);GO:0051963(regulation of synapse assembly);GO:0004872(receptor activity);GO:0030246(carbohydrate binding);GO:0046790(virion binding);GO:0002089(lens morphogenesis in camera-type eye);GO:0002934(desmosome organization);GO:0006826(iron ion transport);GO:0007411(axon guidance);GO:0048593(camera-type eye morphogenesis);GO:0060041(retina development in camera-type eye);GO:0070166(enamel mineralization);GO:1902414(protein localization to cell junction);GO:0016342(catenin complex);GO:0030424(axon);GO:0032584(growth cone membrane);GO:0043005(neuron projection);GO:0043231(intracellular membrane-bounded organelle);GO:0043296(apical junction complex);GO:0044291(cell-cell contact zone);GO:0044291(cell-cell contact zone)","04514(Cell adhesion molecules (CAMs));04520(Adherens junction);05168(Herpes simplex infection);05168(Herpes simplex infection)","K06081","NA","nectin cell adhesion molecule 1 [Source:HGNC Symbol;Acc:HGNC:9706]",{"v":1.79829048630048,"d":"1.80"},{"v":0.220989803921569,"d":"0.22"},{"v":8.13743645357823,"d":"8.14"},{"v":3.02457437210739,"d":"3.02"},{"v":1.03197509153947E-4,"d":"0.00"},{"v":0.0164168859425314,"d":"0.02"},"up","yes"]
["ENSG00000184898","RBM43","ENST00000331426;ENST00000409092","GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0003723(RNA binding)","NA","NA","NA","RNA binding motif protein 43 [Source:HGNC Symbol;Acc:HGNC:24790]",{"v":1.88856089612042,"d":"1.89"},{"v":0.227958900360399,"d":"0.23"},{"v":8.28465523010788,"d":"8.28"},{"v":3.05044166025141,"d":"3.05"},{"v":1.10059210009427E-4,"d":"0.00"},{"v":0.0172718595383713,"d":"0.02"},"up","yes"]
["MSTRG.11451","UBXN7","ENST00000296328;ENST00000429160;ENST00000493566;ENST00000413584","GO:0005654(nucleoplasm);GO:0016604(nuclear body);GO:0005634(nucleus);GO:0005515(protein binding);GO:0005829(cytosol);GO:0043687(post-translational protein modification);GO:0031625(ubiquitin protein ligase binding);GO:0008134(transcription factor binding);GO:0043130(ubiquitin binding);GO:0034098(VCP-NPL4-UFD1 AAA ATPase complex);GO:0034098(VCP-NPL4-UFD1 AAA ATPase complex)","NA","NA","NA","UBX domain protein 7 [Source:HGNC Symbol;Acc:HGNC:29119]",{"v":5.94020798990346,"d":"5.94"},{"v":0.760587005845364,"d":"0.76"},{"v":7.81003086333449,"d":"7.81"},{"v":2.96532824955696,"d":"2.97"},{"v":1.1282719095451E-4,"d":"0.00"},{"v":0.0174701622473963,"d":"0.02"},"up","yes"]
["ENSG00000101966","XIAP","ENST00000371199;ENST00000497640;ENST00000468691;ENST00000497906;ENST00000468503;ENST00000355640;ENST00000422098;ENST00000434753;ENST00000481776","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0016740(transferase activity);GO:0016567(protein ubiquitination);GO:0005515(protein binding);GO:0006974(cellular response to DNA damage stimulus);GO:0006915(apoptotic process);GO:0016055(Wnt signaling pathway);GO:0004869(cysteine-type endopeptidase inhibitor activity);GO:0030414(peptidase inhibitor activity);GO:0010466(negative regulation of peptidase activity);GO:0042802(identical protein binding);GO:0061630(ubiquitin protein ligase activity);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0031398(positive regulation of protein ubiquitination);GO:0042127(regulation of cell proliferation);GO:0090263(positive regulation of canonical Wnt signaling pathway);GO:0043066(negative regulation of apoptotic process);GO:0004842(ubiquitin-protein transferase activity);GO:0043154(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process);GO:1990001(inhibition of cysteine-type endopeptidase activity involved in apoptotic process);GO:0050727(regulation of inflammatory response);GO:0045088(regulation of innate immune response);GO:0030510(regulation of BMP signaling pathway);GO:0043027(cysteine-type endopeptidase inhibitor activity involved in apoptotic process);GO:0055070(copper ion homeostasis);GO:0070424(regulation of nucleotide-binding oligomerization domain containing signaling pathway);GO:1902530(positive regulation of protein linear polyubiquitination);GO:1902530(positive regulation of protein linear polyubiquitination)","04120(Ubiquitin mediated proteolysis);04064(NF-kappa B signaling pathway);04210(Apoptosis);04215(Apoptosis - multiple species);04217(Necroptosis);04510(Focal adhesion);04621(NOD-like receptor signaling pathway);05200(Pathways in cancer);05222(Small cell lung cancer);05166(HTLV-I infection);05145(Toxoplasmosis);01524(Platinum drug resistance);01524(Platinum drug resistance)","K04725","EC:2.3.2.27","X-linked inhibitor of apoptosis [Source:HGNC Symbol;Acc:HGNC:592]",{"v":4.16596747767313,"d":"4.17"},{"v":0.534965168531856,"d":"0.53"},{"v":7.78736209893085,"d":"7.79"},{"v":2.96113471066311,"d":"2.96"},{"v":0.000120893687542321,"d":"0.00"},{"v":0.0184728735977496,"d":"0.02"},"up","yes"]
["ENSG00000085185","BCORL1","ENST00000456822;ENST00000540052;ENST00000607874;ENST00000441294;ENST00000488135;ENST00000218147","GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0016569(covalent chromatin modification);GO:0005886(plasma membrane);GO:0005886(plasma membrane)","NA","NA","NA","BCL6 corepressor like 1 [Source:HGNC Symbol;Acc:HGNC:25657]",{"v":2.05308086630815,"d":"2.05"},{"v":0.257369745247624,"d":"0.26"},{"v":7.97716477643016,"d":"7.98"},{"v":2.995876078554,"d":"3.00"},{"v":0.000123578860689955,"d":"0.00"},{"v":0.0186379390804213,"d":"0.02"},"up","yes"]
["MSTRG.8798","FAM136A","ENST00000037869;ENST00000460307;ENST00000498665;ENST00000438759;ENST00000430566","GO:0005737(cytoplasm);GO:0005737(cytoplasm)","NA","NA","NA","family with sequence similarity 136 member A [Source:HGNC Symbol;Acc:HGNC:25911]",{"v":0.876140162346079,"d":"0.88"},{"v":4.76448016882696,"d":"4.76"},{"v":0.183889979871989,"d":"0.18"},{"v":-2.44308522515837,"d":"-2.44"},{"v":0.000130074250158462,"d":"0.00"},{"v":0.0191048392053491,"d":"0.02"},"down","yes"]
["MSTRG.14408","PEX2","ENST00000357039;ENST00000520203;ENST00000522527;ENST00000518986;ENST00000519956;ENST00000520103","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0046872(metal ion binding);GO:0005515(protein binding);GO:0005777(peroxisome);GO:0005778(peroxisomal membrane);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0061630(ubiquitin protein ligase activity);GO:0016567(protein ubiquitination);GO:0031648(protein destabilization);GO:0007031(peroxisome organization);GO:0016558(protein import into peroxisome matrix);GO:0005779(integral component of peroxisomal membrane);GO:0050680(negative regulation of epithelial cell proliferation);GO:0006635(fatty acid beta-oxidation);GO:0048147(negative regulation of fibroblast proliferation);GO:0000038(very long-chain fatty acid metabolic process);GO:0016593(Cdc73/Paf1 complex);GO:0016593(Cdc73/Paf1 complex)","04146(Peroxisome);04146(Peroxisome)","K06664","NA","peroxisomal biogenesis factor 2 [Source:HGNC Symbol;Acc:HGNC:9717]",{"v":0.982484078084122,"d":"0.98"},{"v":5.25751865003019,"d":"5.26"},{"v":0.186872200268558,"d":"0.19"},{"v":-2.41987612996551,"d":"-2.42"},{"v":0.000130465777038921,"d":"0.00"},{"v":0.0191048392053491,"d":"0.02"},"down","yes"]
["ENSG00000166503","HDGFL3","ENST00000299633;ENST00000568129;ENST00000562702;ENST00000568294","GO:0005654(nucleoplasm);GO:0005634(nucleus);GO:0008083(growth factor activity);GO:0005829(cytosol);GO:0008017(microtubule binding);GO:0015631(tubulin binding);GO:0007026(negative regulation of microtubule depolymerization);GO:0031175(neuron projection development);GO:0046785(microtubule polymerization);GO:0005737(cytoplasm);GO:0008283(cell proliferation);GO:0008283(cell proliferation)","NA","NA","NA","HDGF like 3 [Source:HGNC Symbol;Acc:HGNC:24937]",{"v":0.0506493970343937,"d":"0.05"},{"v":0.288122895773088,"d":"0.29"},{"v":0.175790948159437,"d":"0.18"},{"v":-2.50806730985374,"d":"-2.51"},{"v":1.3161001777559E-4,"d":"0.00"},{"v":0.0191048392053491,"d":"0.02"},"down","yes"]
["MSTRG.12833","IER3","ENST00000259874;ENST00000376377","GO:0043066(negative regulation of apoptotic process);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005515(protein binding);GO:0005829(cytosol);GO:0006915(apoptotic process);GO:0005634(nucleus);GO:0014066(regulation of phosphatidylinositol 3-kinase signaling);GO:0009653(anatomical structure morphogenesis);GO:0010941(regulation of cell death);GO:2001020(regulation of response to DNA damage stimulus);GO:2001020(regulation of response to DNA damage stimulus)","NA","NA","NA","immediate early response 3 [Source:HGNC Symbol;Acc:HGNC:5392]",{"v":7.47925605309735,"d":"7.48"},{"v":0.943987938053097,"d":"0.94"},{"v":7.92304197077215,"d":"7.92"},{"v":2.98605444464248,"d":"2.99"},{"v":0.000138944872495839,"d":"0.00"},{"v":0.0199205778307923,"d":"0.02"},"up","yes"]
["MSTRG.13459","GNA12","ENST00000275364;ENST00000471281;ENST00000407904","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005525(GTP binding);GO:0007264(small GTPase mediated signal transduction);GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0007186(G-protein coupled receptor signaling pathway);GO:0007165(signal transduction);GO:0003924(GTPase activity);GO:0004871(signal transducer activity);GO:0005886(plasma membrane);GO:0001664(G-protein coupled receptor binding);GO:0019001(guanyl nucleotide binding);GO:0031683(G-protein beta/gamma-subunit complex binding);GO:0005925(focal adhesion);GO:0005515(protein binding);GO:0007266(Rho protein signal transduction);GO:0007188(adenylate cyclase-modulating G-protein coupled receptor signaling pathway);GO:0005834(heterotrimeric G-protein complex);GO:0016328(lateral plasma membrane);GO:0007596(blood coagulation);GO:0030168(platelet activation);GO:0032006(regulation of TOR signaling);GO:0032434(regulation of proteasomal ubiquitin-dependent protein catabolic process);GO:0031526(brush border membrane);GO:0031752(D5 dopamine receptor binding);GO:0001701(in utero embryonic development);GO:0008360(regulation of cell shape);GO:0010762(regulation of fibroblast migration);GO:0030154(cell differentiation);GO:0035556(intracellular signal transduction);GO:0042493(response to drug);GO:0042733(embryonic digit morphogenesis);GO:0042733(embryonic digit morphogenesis)","04010(MAPK signaling pathway);04072(Phospholipase D signaling pathway);04071(Sphingolipid signaling pathway);04022(cGMP - PKG signaling pathway);04810(Regulation of actin cytoskeleton);04270(Vascular smooth muscle contraction);04730(Long-term depression);05200(Pathways in cancer);05200(Pathways in cancer)","K04346","NA","G protein subunit alpha 12 [Source:HGNC Symbol;Acc:HGNC:4380]",{"v":0.878420599509804,"d":"0.88"},{"v":4.54984605669935,"d":"4.55"},{"v":0.193066004555558,"d":"0.19"},{"v":-2.37283394083615,"d":"-2.37"},{"v":1.522940898927E-4,"d":"0.00"},{"v":0.021568186169804,"d":"0.02"},"down","yes"]
["MSTRG.2726","THAP12","ENST00000260045;ENST00000528993;ENST00000525277;ENST00000529901","GO:0003676(nucleic acid binding);GO:0046872(metal ion binding);GO:0046983(protein dimerization activity);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0005737(cytoplasm);GO:0005634(nucleus);GO:0000981(RNA polymerase II transcription factor activity, sequence-specific DNA binding);GO:0005654(nucleoplasm);GO:0006950(response to stress);GO:0007165(signal transduction);GO:0008285(negative regulation of cell proliferation);GO:0008285(negative regulation of cell proliferation)","NA","NA","NA","THAP domain containing 12 [Source:HGNC Symbol;Acc:HGNC:9440]",{"v":1.22305785828912,"d":"1.22"},{"v":6.29285479979293,"d":"6.29"},{"v":0.19435659922256,"d":"0.19"},{"v":-2.36322200082473,"d":"-2.36"},{"v":1.57062338282476E-4,"d":"0.00"},{"v":0.0219754811382458,"d":"0.02"},"down","yes"]
["MSTRG.14333","THAP1","ENST00000254250;ENST00000532093;ENST00000345117","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0043231(intracellular membrane-bounded organelle);GO:0046872(metal ion binding);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0001650(fibrillar center);GO:0008270(zinc ion binding);GO:0005515(protein binding);GO:0007049(cell cycle);GO:0005654(nucleoplasm);GO:0042802(identical protein binding);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:0001078(transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0007346(regulation of mitotic cell cycle);GO:0043565(sequence-specific DNA binding);GO:0016605(PML body);GO:0001935(endothelial cell proliferation);GO:0001935(endothelial cell proliferation)","NA","NA","NA","THAP domain containing 1 [Source:HGNC Symbol;Acc:HGNC:20856]",{"v":0.950982194151097,"d":"0.95"},{"v":4.96387365718928,"d":"4.96"},{"v":0.191580660554035,"d":"0.19"},{"v":-2.38397616184559,"d":"-2.38"},{"v":0.000159921984546868,"d":"0.00"},{"v":0.0221092143636045,"d":"0.02"},"down","yes"]
["MSTRG.1850","IFIT2","ENST00000371826;ENST00000611722;ENST00000638108","GO:0003723(RNA binding);GO:0005737(cytoplasm);GO:0005783(endoplasmic reticulum);GO:0005515(protein binding);GO:0006915(apoptotic process);GO:0002376(immune system process);GO:0045087(innate immune response);GO:0051607(defense response to virus);GO:0035457(cellular response to interferon-alpha);GO:0005829(cytosol);GO:0009615(response to virus);GO:0043065(positive regulation of apoptotic process);GO:0032091(negative regulation of protein binding);GO:0060337(type I interferon signaling pathway);GO:0008637(apoptotic mitochondrial changes);GO:0008637(apoptotic mitochondrial changes)","NA","NA","NA","interferon induced protein with tetratricopeptide repeats 2 [Source:HGNC Symbol;Acc:HGNC:5409]",{"v":2.19892531133067,"d":"2.20"},{"v":11.1360614069792,"d":"11.14"},{"v":0.197459876608848,"d":"0.20"},{"v":-2.34036856412001,"d":"-2.34"},{"v":1.75789393270879E-4,"d":"0.00"},{"v":0.0237715525670693,"d":"0.02"},"down","yes"]
["ENSG00000155961","RAB39B","ENST00000369454","GO:0006810(transport);GO:0016020(membrane);GO:0015031(protein transport);GO:0005525(GTP binding);GO:0000166(nucleotide binding);GO:0003924(GTPase activity);GO:0005794(Golgi apparatus);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0006914(autophagy);GO:0030659(cytoplasmic vesicle membrane);GO:0031410(cytoplasmic vesicle);GO:0016192(vesicle-mediated transport);GO:0043005(neuron projection);GO:0031489(myosin V binding);GO:0031982(vesicle);GO:0010506(regulation of autophagy);GO:0050808(synapse organization);GO:0005622(intracellular)","NA","NA","NA","RAB39B, member RAS oncogene family [Source:HGNC Symbol;Acc:HGNC:16499]",{"v":0.332516,"d":"0.33"},{"v":1.779442,"d":"1.78"},{"v":0.186865320701658,"d":"0.19"},{"v":-2.41992924273313,"d":"-2.42"},{"v":1.76040086176523E-4,"d":"0.00"},{"v":0.0237715525670693,"d":"0.02"},"down","yes"]
["ENSG00000158406","HIST1H4H","ENST00000634956;ENST00000635491;ENST00000634560","GO:0005634(nucleus);GO:0003723(RNA binding);GO:0016020(membrane);GO:0003677(DNA binding);GO:0046982(protein heterodimerization activity);GO:0006334(nucleosome assembly);GO:0000786(nucleosome);GO:0005694(chromosome);GO:0005515(protein binding);GO:0006352(DNA-templated transcription, initiation);GO:0005576(extracellular region);GO:0005654(nucleoplasm);GO:0070062(extracellular exosome);GO:0044267(cellular protein metabolic process);GO:1902036(regulation of hematopoietic stem cell differentiation);GO:0043234(protein complex);GO:0000784(nuclear chromosome, telomeric region);GO:0034080(CENP-A containing nucleosome assembly);GO:0031012(extracellular matrix);GO:0045815(positive regulation of gene expression, epigenetic);GO:0019904(protein domain specific binding);GO:0042393(histone binding);GO:1904837(beta-catenin-TCF complex assembly);GO:0045652(regulation of megakaryocyte differentiation);GO:0006335(DNA replication-dependent nucleosome assembly);GO:0006336(DNA replication-independent nucleosome assembly);GO:0000228(nuclear chromosome);GO:0060964(regulation of gene silencing by miRNA);GO:0000183(chromatin silencing at rDNA);GO:0045814(negative regulation of gene expression, epigenetic);GO:0006303(double-strand break repair via nonhomologous end joining);GO:0051290(protein heterotetramerization);GO:0045653(negative regulation of megakaryocyte differentiation);GO:0016233(telomere capping);GO:0032200(telomere organization);GO:0000788(nuclear nucleosome);GO:0000788(nuclear nucleosome)","05203(Viral carcinogenesis);05322(Systemic lupus erythematosus);05034(Alcoholism);05034(Alcoholism)","NA","NA","histone cluster 1 H4 family member h [Source:HGNC Symbol;Acc:HGNC:4788]",{"v":0.345761,"d":"0.35"},{"v":1.88010955987055,"d":"1.88"},{"v":0.183904708204242,"d":"0.18"},{"v":-2.44296967975979,"d":"-2.44"},{"v":0.000184366780333222,"d":"0.00"},{"v":0.0243439270374613,"d":"0.02"},"down","yes"]
["MSTRG.4310","SPTSSA","ENST00000298130","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0006629(lipid metabolic process);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0006665(sphingolipid metabolic process);GO:0005515(protein binding);GO:0030148(sphingolipid biosynthetic process);GO:0004758(serine C-palmitoyltransferase activity);GO:0046513(ceramide biosynthetic process);GO:0017059(serine C-palmitoyltransferase complex)","NA","NA","NA","serine palmitoyltransferase small subunit A [Source:HGNC Symbol;Acc:HGNC:20361]",{"v":0.789652,"d":"0.79"},{"v":4.069687,"d":"4.07"},{"v":0.194032612336035,"d":"0.19"},{"v":-2.36562893886014,"d":"-2.37"},{"v":1.84471332067218E-4,"d":"0.00"},{"v":0.0243439270374613,"d":"0.02"},"down","yes"]
["MSTRG.15443","SH2D1A;TEX13D","ENST00000371139;ENST00000632372;ENST00000360027;ENST00000477673","GO:0005737(cytoplasm);GO:0009967(positive regulation of signal transduction);GO:0005515(protein binding);GO:0002376(immune system process);GO:0045087(innate immune response);GO:0002250(adaptive immune response);GO:0050776(regulation of immune response);GO:0005070(SH3/SH2 adaptor activity);GO:0005829(cytosol);GO:0007267(cell-cell signaling);GO:0006959(humoral immune response);GO:0006968(cellular defense response);GO:0045954(positive regulation of natural killer cell mediated cytotoxicity);GO:0045954(positive regulation of natural killer cell mediated cytotoxicity)","04650(Natural killer cell mediated cytotoxicity);05162(Measles);05162(Measles)","K07990","NA","SH2 domain containing 1A [Source:HGNC Symbol;Acc:HGNC:10820];TEX13 family member D [Source:HGNC Symbol;Acc:HGNC:52278]",{"v":1.05135696190741,"d":"1.05"},{"v":5.25346543556235,"d":"5.25"},{"v":0.200126368927917,"d":"0.20"},{"v":-2.32101682361985,"d":"-2.32"},{"v":1.96495752674476E-4,"d":"0.00"},{"v":0.0256393839978504,"d":"0.03"},"down","yes"]
["ENSG00000180884","ZNF792","ENST00000404801;ENST00000605484","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0005622(intracellular);GO:0005515(protein binding);GO:0042802(identical protein binding);GO:0042802(identical protein binding)","NA","NA","NA","zinc finger protein 792 [Source:HGNC Symbol;Acc:HGNC:24751]",{"v":0.277378588568729,"d":"0.28"},{"v":1.45278779570146,"d":"1.45"},{"v":0.190928495812976,"d":"0.19"},{"v":-2.38889565584351,"d":"-2.39"},{"v":0.000211027929881239,"d":"0.00"},{"v":0.0269675428823653,"d":"0.03"},"down","yes"]
["MSTRG.183","SPEN","ENST00000375759;MSTRG.183.2;ENST00000438066;ENST00000487496","GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0007219(Notch signaling pathway);GO:0070062(extracellular exosome);GO:0000398(mRNA splicing, via spliceosome);GO:0016032(viral process);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0045892(negative regulation of transcription, DNA-templated);GO:0001085(RNA polymerase II transcription factor binding);GO:0001191(transcriptional repressor activity, RNA polymerase II transcription factor binding);GO:0017053(transcriptional repressor complex);GO:0050769(positive regulation of neurogenesis);GO:0050769(positive regulation of neurogenesis)","NA","NA","NA","spen family transcriptional repressor [Source:HGNC Symbol;Acc:HGNC:17575]",{"v":10.3843858961938,"d":"10.38"},{"v":1.45305850804874,"d":"1.45"},{"v":7.14657106969397,"d":"7.15"},{"v":2.83725120170617,"d":"2.84"},{"v":2.11318901429023E-4,"d":"0.00"},{"v":0.0269675428823653,"d":"0.03"},"up","yes"]
["MSTRG.1510","ZNF672","ENST00000306562;ENST00000505503;ENST00000515369;ENST00000502697;ENST00000428515","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0005654(nucleoplasm);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding)","NA","NA","NA","zinc finger protein 672 [Source:HGNC Symbol;Acc:HGNC:26179]",{"v":4.2697227035552,"d":"4.27"},{"v":0.586496770114943,"d":"0.59"},{"v":7.28004470121534,"d":"7.28"},{"v":2.86394730894371,"d":"2.86"},{"v":0.000214862194896306,"d":"0.00"},{"v":0.0270052985551273,"d":"0.03"},"up","yes"]
["ENSG00000215712","TMEM242","ENST00000400788;ENST00000367144","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005515(protein binding);GO:0005515(protein binding)","NA","NA","NA","transmembrane protein 242 [Source:HGNC Symbol;Acc:HGNC:17206]",{"v":0.234373500215332,"d":"0.23"},{"v":1.21776710292851,"d":"1.22"},{"v":0.192461678141663,"d":"0.19"},{"v":-2.3773568815931,"d":"-2.38"},{"v":0.000216265630382058,"d":"0.00"},{"v":0.0270052985551273,"d":"0.03"},"down","yes"]
["ENSG00000130684","ZNF337","ENST00000252979;ENST00000481610;ENST00000376436","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0005622(intracellular);GO:0005515(protein binding);GO:0005515(protein binding)","NA","NA","NA","zinc finger protein 337 [Source:HGNC Symbol;Acc:HGNC:15809]",{"v":0.471057657860319,"d":"0.47"},{"v":2.40474251425582,"d":"2.40"},{"v":0.195886942185199,"d":"0.20"},{"v":-2.35190686406354,"d":"-2.35"},{"v":0.000225287564676703,"d":"0.00"},{"v":0.0275947638588479,"d":"0.03"},"down","yes"]
["MSTRG.3010","ERC1","ENST00000542302;ENST00000360905;ENST00000587595;ENST00000440394;ENST00000543086;ENST00000355446;ENST00000544277;ENST00000536573;ENST00000538971;ENST00000589132;ENST00000546231;ENST00000347735;ENST00000543151;ENST00000397203;ENST00000539007;ENST00000589028","GO:0048786(presynaptic active zone);GO:0006810(transport);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0015031(protein transport);GO:0006355(regulation of transcription, DNA-templated);GO:0005794(Golgi apparatus);GO:0005515(protein binding);GO:0000139(Golgi membrane);GO:0007275(multicellular organism development);GO:0045296(cadherin binding);GO:0043066(negative regulation of apoptotic process);GO:0051092(positive regulation of NF-kappaB transcription factor activity);GO:0042734(presynaptic membrane);GO:0017137(Rab GTPase binding);GO:0008385(IkappaB kinase complex);GO:0043522(leucine zipper domain binding);GO:0007252(I-kappaB phosphorylation);GO:0042147(retrograde transport, endosome to Golgi);GO:0045202(synapse);GO:0030165(PDZ domain binding);GO:0030165(PDZ domain binding)","04064(NF-kappa B signaling pathway);04064(NF-kappa B signaling pathway)","K16072","NA","ELKS/RAB6-interacting/CAST family member 1 [Source:HGNC Symbol;Acc:HGNC:17072]",{"v":1.23679605398991,"d":"1.24"},{"v":0.167529238430733,"d":"0.17"},{"v":7.38256835388933,"d":"7.38"},{"v":2.88412280907825,"d":"2.88"},{"v":0.000225738617634595,"d":"0.00"},{"v":0.0275947638588479,"d":"0.03"},"up","yes"]
["MSTRG.13995","C7orf73","ENST00000507606;ENST00000509448;ENST00000515197;ENST00000422968","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005739(mitochondrion);GO:0031966(mitochondrial membrane);GO:0031966(mitochondrial membrane)","NA","NA","NA","chromosome 7 open reading frame 73 [Source:HGNC Symbol;Acc:HGNC:41909]",{"v":7.67874350933063,"d":"7.68"},{"v":1.07768149148073,"d":"1.08"},{"v":7.12524393341865,"d":"7.13"},{"v":2.83293940581517,"d":"2.83"},{"v":2.33833242102918E-4,"d":"0.00"},{"v":0.0282496268626148,"d":"0.03"},"up","yes"]
["MSTRG.2457","AHNAK","ENST00000378024;ENST00000257247;ENST00000530124;ENST00000525875;ENST00000530285;ENST00000531324","GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005765(lysosomal membrane);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0045121(membrane raft);GO:0005925(focal adhesion);GO:0045296(cadherin binding);GO:0070062(extracellular exosome);GO:0042383(sarcolemma);GO:0043484(regulation of RNA splicing);GO:0030315(T-tubule);GO:0031982(vesicle);GO:1901385(regulation of voltage-gated calcium channel activity);GO:0051259(protein oligomerization);GO:0044548(S100 protein binding);GO:0015629(actin cytoskeleton);GO:0043034(costamere);GO:0044291(cell-cell contact zone);GO:0097493(structural molecule activity conferring elasticity);GO:0097493(structural molecule activity conferring elasticity)","NA","NA","NA","AHNAK nucleoprotein [Source:HGNC Symbol;Acc:HGNC:347]",{"v":74.2392586515284,"d":"74.24"},{"v":10.5806825199075,"d":"10.58"},{"v":7.01649052524236,"d":"7.02"},{"v":2.81074961061004,"d":"2.81"},{"v":2.3596088914782E-4,"d":"0.00"},{"v":0.0282496268626148,"d":"0.03"},"up","yes"]
["ENSG00000069020","MAST4","ENST00000406374;ENST00000485768;ENST00000450827;ENST00000443808;ENST00000452953;ENST00000411628;ENST00000470421;ENST00000261569;ENST00000436277;ENST00000403625;ENST00000490016;ENST00000403666","GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0016740(transferase activity);GO:0000287(magnesium ion binding);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0005622(intracellular);GO:0035556(intracellular signal transduction);GO:0018105(peptidyl-serine phosphorylation);GO:0018105(peptidyl-serine phosphorylation)","NA","NA","NA","microtubule associated serine/threonine kinase family member 4 [Source:HGNC Symbol;Acc:HGNC:19037]",{"v":0.645650238091993,"d":"0.65"},{"v":0.086952719318569,"d":"0.09"},{"v":7.42530243046824,"d":"7.43"},{"v":2.89244978767113,"d":"2.89"},{"v":2.47223580026294E-4,"d":"0.00"},{"v":0.0292959942331159,"d":"0.03"},"up","yes"]
["MSTRG.3433","GDF11","ENST00000257868","GO:0043231(intracellular membrane-bounded organelle);GO:0005654(nucleoplasm);GO:0008083(growth factor activity);GO:0005576(extracellular region);GO:0005125(cytokine activity);GO:0005615(extracellular space);GO:0007399(nervous system development);GO:0001501(skeletal system development);GO:0001656(metanephros development);GO:0001657(ureteric bud development);GO:0008285(negative regulation of cell proliferation);GO:0009887(animal organ morphogenesis);GO:0009952(anterior/posterior pattern specification);GO:0021512(spinal cord anterior/posterior patterning);GO:0031016(pancreas development);GO:0045596(negative regulation of cell differentiation);GO:0048469(cell maturation);GO:0048593(camera-type eye morphogenesis);GO:0060021(palate development);GO:0060395(SMAD protein signal transduction);GO:0005515(protein binding);GO:0005575(cellular_component);GO:0043234(protein complex);GO:0005160(transforming growth factor beta receptor binding);GO:0010862(positive regulation of pathway-restricted SMAD protein phosphorylation);GO:0042981(regulation of apoptotic process);GO:0043408(regulation of MAPK cascade);GO:0048468(cell development);GO:0007498(mesoderm development)","NA","NA","NA","growth differentiation factor 11 [Source:HGNC Symbol;Acc:HGNC:4216]",{"v":1.24188,"d":"1.24"},{"v":0.17128,"d":"0.17"},{"v":7.25058383932742,"d":"7.25"},{"v":2.8580971700502,"d":"2.86"},{"v":0.000253383323788001,"d":"0.00"},{"v":0.0297226317085864,"d":"0.03"},"up","yes"]
["MSTRG.12653","RREB1","ENST00000379938;ENST00000334984;ENST00000475946;ENST00000379933;ENST00000471433;ENST00000349384;ENST00000483150;ENST00000491191;ENST00000611109","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016607(nuclear speck);GO:0046872(metal ion binding);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0001650(fibrillar center);GO:0045893(positive regulation of transcription, DNA-templated);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0070062(extracellular exosome);GO:0001228(transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0007275(multicellular organism development);GO:0006366(transcription from RNA polymerase II promoter);GO:0000977(RNA polymerase II regulatory region sequence-specific DNA binding);GO:0007265(Ras protein signal transduction);GO:0010634(positive regulation of epithelial cell migration);GO:0016604(nuclear body);GO:0000979(RNA polymerase II core promoter sequence-specific DNA binding);GO:1900026(positive regulation of substrate adhesion-dependent cell spreading);GO:2000394(positive regulation of lamellipodium morphogenesis);GO:0033601(positive regulation of mammary gland epithelial cell proliferation);GO:1903691(positive regulation of wound healing, spreading of epidermal cells);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0045892(negative regulation of transcription, DNA-templated);GO:0045892(negative regulation of transcription, DNA-templated)","NA","NA","NA","ras responsive element binding protein 1 [Source:HGNC Symbol;Acc:HGNC:10449]",{"v":1.51112005181407,"d":"1.51"},{"v":0.213957945809667,"d":"0.21"},{"v":7.06269657850583,"d":"7.06"},{"v":2.82021911801004,"d":"2.82"},{"v":2.58973563987773E-4,"d":"0.00"},{"v":0.0300745999859,"d":"0.03"},"up","yes"]
["ENSG00000257743","MGAM2","ENST00000477922;ENST00000550469","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0030246(carbohydrate binding);GO:0003824(catalytic activity);GO:0005975(carbohydrate metabolic process);GO:0004553(hydrolase activity, hydrolyzing O-glycosyl compounds);GO:0004339(glucan 1,4-alpha-glucosidase activity);GO:0004339(glucan 1,4-alpha-glucosidase activity)","00052(Galactose metabolism);00500(Starch and sucrose metabolism);04973(Carbohydrate digestion and absorption);04973(Carbohydrate digestion and absorption)","K12047","EC:3.2.1.20;EC:3.2.1.3","maltase-glucoamylase 2 (putative) [Source:HGNC Symbol;Acc:HGNC:28101]",{"v":0.732040639181573,"d":"0.73"},{"v":0.0982960541533938,"d":"0.10"},{"v":7.4473044262713,"d":"7.45"},{"v":2.89671833234479,"d":"2.90"},{"v":0.00026461571000015,"d":"0.00"},{"v":0.0304255667349677,"d":"0.03"},"up","yes"]
["MSTRG.6404","KDM6B","ENST00000448097;ENST00000254846;MSTRG.6404.1;ENST00000575521;ENST00000572030;ENST00000571047","GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0005634(nucleus);GO:0048333(mesodermal cell differentiation);GO:0046872(metal ion binding);GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0016569(covalent chromatin modification);GO:0005515(protein binding);GO:0051213(dioxygenase activity);GO:0006954(inflammatory response);GO:0071558(histone demethylase activity (H3-K27 specific));GO:0071557(histone H3-K27 demethylation);GO:0005654(nucleoplasm);GO:0032452(histone demethylase activity);GO:0003682(chromatin binding);GO:0008013(beta-catenin binding);GO:0043565(sequence-specific DNA binding);GO:0002437(inflammatory response to antigenic stimulus);GO:0010468(regulation of gene expression);GO:0014823(response to activity);GO:0016577(histone demethylation);GO:0021766(hippocampus development);GO:0045165(cell fate commitment);GO:0045446(endothelial cell differentiation);GO:0055007(cardiac muscle cell differentiation);GO:0060992(response to fungicide);GO:0070301(cellular response to hydrogen peroxide);GO:0070301(cellular response to hydrogen peroxide)","NA","NA","NA","lysine demethylase 6B [Source:HGNC Symbol;Acc:HGNC:29012]",{"v":22.3477899428611,"d":"22.35"},{"v":3.24871958920252,"d":"3.25"},{"v":6.8789531780879,"d":"6.88"},{"v":2.78218903590294,"d":"2.78"},{"v":0.000277621486304146,"d":"0.00"},{"v":0.0316080227495103,"d":"0.03"},"up","yes"]
["MSTRG.7007",null,"MSTRG.7007.1","NA","NA","NA","NA",null,{"v":26.527411,"d":"26.53"},{"v":3.700911,"d":"3.70"},{"v":7.16780571053992,"d":"7.17"},{"v":2.8415315324514,"d":"2.84"},{"v":0.000284895712876918,"d":"0.00"},{"v":0.0320342708051081,"d":"0.03"},"up","yes"]
["ENSG00000148840","PPRC1","ENST00000278070;ENST00000495914;ENST00000370012;ENST00000489648;ENST00000413464;ENST00000462933","GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0008134(transcription factor binding);GO:0003712(transcription cofactor activity);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0007005(mitochondrion organization);GO:0030374(ligand-dependent nuclear receptor transcription coactivator activity);GO:0001104(RNA polymerase II transcription cofactor activity);GO:0051091(positive regulation of sequence-specific DNA binding transcription factor activity);GO:1903506(regulation of nucleic acid-templated transcription);GO:1903506(regulation of nucleic acid-templated transcription)","NA","NA","NA","peroxisome proliferator-activated receptor gamma, coactivator-related 1 [Source:HGNC Symbol;Acc:HGNC:30025]",{"v":3.38676896406891,"d":"3.39"},{"v":0.482725483839212,"d":"0.48"},{"v":7.01593157488447,"d":"7.02"},{"v":2.81063467750667,"d":"2.81"},{"v":0.000288775401136831,"d":"0.00"},{"v":0.0320342708051081,"d":"0.03"},"up","yes"]
["MSTRG.12161","DHFR","ENST00000439211;ENST00000513314;ENST00000508282","GO:0003723(RNA binding);GO:0005737(cytoplasm);GO:0009165(nucleotide biosynthetic process);GO:0016491(oxidoreductase activity);GO:0050661(NADP binding);GO:0055114(oxidation-reduction process);GO:0005739(mitochondrion);GO:0006730(one-carbon metabolic process);GO:0005515(protein binding);GO:0006545(glycine biosynthetic process);GO:0003729(mRNA binding);GO:0005575(cellular_component);GO:0005829(cytosol);GO:0004146(dihydrofolate reductase activity);GO:0008144(drug binding);GO:0051000(positive regulation of nitric-oxide synthase activity);GO:0000083(regulation of transcription involved in G1/S transition of mitotic cell cycle);GO:0046655(folic acid metabolic process);GO:0000900(translation repressor activity, nucleic acid binding);GO:0005542(folic acid binding);GO:0033560(folate reductase activity);GO:0051870(methotrexate binding);GO:0070402(NADPH binding);GO:1990825(sequence-specific mRNA binding);GO:0006729(tetrahydrobiopterin biosynthetic process);GO:0017148(negative regulation of translation);GO:0031103(axon regeneration);GO:0031427(response to methotrexate);GO:0046452(dihydrofolate metabolic process);GO:0046653(tetrahydrofolate metabolic process);GO:0046654(tetrahydrofolate biosynthetic process);GO:2000121(regulation of removal of superoxide radicals);GO:2000121(regulation of removal of superoxide radicals)","00790(Folate biosynthesis);00670(One carbon pool by folate);01523(Antifolate resistance);01523(Antifolate resistance)","K00287","EC:1.5.1.3","dihydrofolate reductase [Source:HGNC Symbol;Acc:HGNC:2861]",{"v":0.313089542299841,"d":"0.31"},{"v":1.54810784395555,"d":"1.55"},{"v":0.20224013690149,"d":"0.20"},{"v":-2.30585874966243,"d":"-2.31"},{"v":0.000289640784856312,"d":"0.00"},{"v":0.0320342708051081,"d":"0.03"},"down","yes"]
["MSTRG.2864","PAFAH1B2","ENST00000527958;ENST00000419197;ENST00000533677;ENST00000533206","GO:0005737(cytoplasm);GO:0005730(nucleolus);GO:0005829(cytosol);GO:0016787(hydrolase activity);GO:0001650(fibrillar center);GO:0006629(lipid metabolic process);GO:0016042(lipid catabolic process);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0070062(extracellular exosome);GO:0043312(neutrophil degranulation);GO:0034774(secretory granule lumen);GO:1904813(ficolin-1-rich granule lumen);GO:0016239(positive regulation of macroautophagy);GO:0007420(brain development);GO:0004623(phospholipase A2 activity);GO:0003847(1-alkyl-2-acetylglycerophosphocholine esterase activity);GO:0042803(protein homodimerization activity);GO:0046982(protein heterodimerization activity);GO:0047179(platelet-activating factor acetyltransferase activity);GO:0007283(spermatogenesis);GO:0007283(spermatogenesis)","00565(Ether lipid metabolism);00565(Ether lipid metabolism)","K16795","EC:3.1.1.47","platelet activating factor acetylhydrolase 1b catalytic subunit 2 [Source:HGNC Symbol;Acc:HGNC:8575]",{"v":6.60635401717342,"d":"6.61"},{"v":0.959849727195946,"d":"0.96"},{"v":6.88269614502352,"d":"6.88"},{"v":2.78297381973846,"d":"2.78"},{"v":0.00029877241410384,"d":"0.00"},{"v":0.032500887451075,"d":"0.03"},"up","yes"]
["MSTRG.2074","BET1L","ENST00000382762;ENST00000410108;ENST00000479463;ENST00000325147;ENST00000486280","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0015031(protein transport);GO:0005829(cytosol);GO:0005794(Golgi apparatus);GO:0000139(Golgi membrane);GO:0061025(membrane fusion);GO:0006888(ER to Golgi vesicle-mediated transport);GO:0005484(SNAP receptor activity);GO:0042147(retrograde transport, endosome to Golgi);GO:0031201(SNARE complex);GO:0005768(endosome);GO:2000156(regulation of retrograde vesicle-mediated transport, Golgi to ER);GO:2000156(regulation of retrograde vesicle-mediated transport, Golgi to ER)","04130(SNARE interactions in vesicular transport);04130(SNARE interactions in vesicular transport)","K08504","NA","Bet1 golgi vesicular membrane trafficking protein like [Source:HGNC Symbol;Acc:HGNC:19348]",{"v":1.37471142476732,"d":"1.37"},{"v":6.54829250568769,"d":"6.55"},{"v":0.209934333808894,"d":"0.21"},{"v":-2.25198996272543,"d":"-2.25"},{"v":2.99457070288903E-4,"d":"0.00"},{"v":0.032500887451075,"d":"0.03"},"down","yes"]
["ENSG00000141905","NFIC","ENST00000589969;ENST00000641145;ENST00000589164;ENST00000341919;ENST00000395111;ENST00000589123;ENST00000443272;ENST00000590282;ENST00000589537","GO:0005634(nucleus);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0005622(intracellular);GO:0001650(fibrillar center);GO:0006260(DNA replication);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0006366(transcription from RNA polymerase II promoter);GO:0001077(transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0001159(core promoter proximal region DNA binding);GO:0003690(double-stranded DNA binding);GO:0042475(odontogenesis of dentin-containing tooth);GO:0045892(negative regulation of transcription, DNA-templated);GO:0045892(negative regulation of transcription, DNA-templated)","NA","NA","NA","nuclear factor I C [Source:HGNC Symbol;Acc:HGNC:7786]",{"v":1.39053967860422,"d":"1.39"},{"v":0.198652222834405,"d":"0.20"},{"v":6.99986971584689,"d":"7.00"},{"v":2.80732807033606,"d":"2.81"},{"v":0.000306686986360224,"d":"0.00"},{"v":0.0329773701166785,"d":"0.03"},"up","yes"]
["MSTRG.2933","CBL","ENST00000264033;ENST00000634840;ENST00000637974","GO:0014068(positive regulation of phosphatidylinositol 3-kinase signaling);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0046872(metal ion binding);GO:0005829(cytosol);GO:0016740(transferase activity);GO:0016567(protein ubiquitination);GO:0005509(calcium ion binding);GO:0004871(signal transducer activity);GO:0004842(ubiquitin-protein transferase activity);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0023051(regulation of signaling);GO:0007166(cell surface receptor signaling pathway);GO:0006355(regulation of transcription, DNA-templated);GO:0042629(mast cell granule);GO:0061630(ubiquitin protein ligase activity);GO:0001784(phosphotyrosine residue binding);GO:0045296(cadherin binding);GO:0061024(membrane organization);GO:0042787(protein ubiquitination involved in ubiquitin-dependent protein catabolic process);GO:0043066(negative regulation of apoptotic process);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0048260(positive regulation of receptor-mediated endocytosis);GO:0042059(negative regulation of epidermal growth factor receptor signaling pathway);GO:0008543(fibroblast growth factor receptor signaling pathway);GO:0017124(SH3 domain binding);GO:0035635(entry of bacterium into host cell);GO:0007179(transforming growth factor beta receptor signaling pathway);GO:0045121(membrane raft);GO:0046875(ephrin receptor binding);GO:0045742(positive regulation of epidermal growth factor receptor signaling pathway);GO:0016600(flotillin complex);GO:0005154(epidermal growth factor receptor binding);GO:0019901(protein kinase binding);GO:0030971(receptor tyrosine kinase binding);GO:0036312(phosphatidylinositol 3-kinase regulatory subunit binding);GO:1990782(protein tyrosine kinase binding);GO:0000209(protein polyubiquitination);GO:0006513(protein monoubiquitination);GO:0006974(cellular response to DNA damage stimulus);GO:0007173(epidermal growth factor receptor signaling pathway);GO:0007175(negative regulation of epidermal growth factor-activated receptor activity);GO:0008584(male gonad development);GO:0010332(response to gamma radiation);GO:0014823(response to activity);GO:0033574(response to testosterone);GO:0036120(cellular response to platelet-derived growth factor stimulus);GO:0042594(response to starvation);GO:0043303(mast cell degranulation);GO:0045471(response to ethanol);GO:0046677(response to antibiotic);GO:0070997(neuron death);GO:0071364(cellular response to epidermal growth factor stimulus);GO:0090650(cellular response to oxygen-glucose deprivation);GO:1901215(negative regulation of neuron death);GO:1990090(cellular response to nerve growth factor stimulus);GO:0005925(focal adhesion);GO:0030424(axon);GO:0030426(growth cone);GO:0048471(perinuclear region of cytoplasm);GO:0048471(perinuclear region of cytoplasm)","04120(Ubiquitin mediated proteolysis);04012(ErbB signaling pathway);04144(Endocytosis);04660(T cell receptor signaling pathway);04910(Insulin signaling pathway);05200(Pathways in cancer);05205(Proteoglycans in cancer);05220(Chronic myeloid leukemia);05100(Bacterial invasion of epithelial cells);05100(Bacterial invasion of epithelial cells)","K04707","EC:2.3.2.27","Cbl proto-oncogene [Source:HGNC Symbol;Acc:HGNC:1541]",{"v":14.0892420343271,"d":"14.09"},{"v":2.08423599744463,"d":"2.08"},{"v":6.75990725215435,"d":"6.76"},{"v":2.75700345245792,"d":"2.76"},{"v":0.000314274749197036,"d":"0.00"},{"v":0.0333117143290298,"d":"0.03"},"up","yes"]
["MSTRG.6495","ALKBH5","ENST00000399138;ENST00000490106;ENST00000541285","GO:0003723(RNA binding);GO:0006397(mRNA processing);GO:0005634(nucleus);GO:0016607(nuclear speck);GO:0005794(Golgi apparatus);GO:0046872(metal ion binding);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0030154(cell differentiation);GO:0051213(dioxygenase activity);GO:0006406(mRNA export from nucleus);GO:0007283(spermatogenesis);GO:0035515(oxidative RNA demethylase activity);GO:0035553(oxidative single-stranded RNA demethylation);GO:0016706(oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors);GO:0001666(response to hypoxia);GO:0006307(DNA dealkylation involved in DNA repair);GO:0006307(DNA dealkylation involved in DNA repair)","NA","NA","NA","alkB homolog 5, RNA demethylase [Source:HGNC Symbol;Acc:HGNC:25996]",{"v":1.9155105291536,"d":"1.92"},{"v":9.01996146677116,"d":"9.02"},{"v":0.212363493592538,"d":"0.21"},{"v":-2.23539231433695,"d":"-2.24"},{"v":3.15724735726927E-4,"d":"0.00"},{"v":0.0333117143290298,"d":"0.03"},"down","yes"]
["MSTRG.15366","XIST","ENST00000429829;ENST00000602863;ENST00000602587;ENST00000417942;ENST00000434839;ENST00000635841;MSTRG.15366.11;ENST00000445814;ENST00000602495;ENST00000416330;MSTRG.15366.8","NA","NA","NA","NA","X inactive specific transcript (non-protein coding) [Source:HGNC Symbol;Acc:HGNC:12810]",{"v":12.8698548386854,"d":"12.87"},{"v":1.90684864911578,"d":"1.91"},{"v":6.74927967914666,"d":"6.75"},{"v":2.75473353790039,"d":"2.75"},{"v":0.000318401816113176,"d":"0.00"},{"v":0.0333117143290298,"d":"0.03"},"up","yes"]
["MSTRG.4338","PNN","ENST00000216832;ENST00000553331;ENST00000554117;ENST00000554902","GO:0003723(RNA binding);GO:0006397(mRNA processing);GO:0008380(RNA splicing);GO:0005634(nucleus);GO:0016607(nuclear speck);GO:0016020(membrane);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0005681(spliceosomal complex);GO:0030054(cell junction);GO:0005886(plasma membrane);GO:0000398(mRNA splicing, via spliceosome);GO:0007155(cell adhesion);GO:0035145(exon-exon junction complex);GO:0005198(structural molecule activity);GO:0005911(cell-cell junction);GO:0071013(catalytic step 2 spliceosome);GO:0030057(desmosome);GO:0005882(intermediate filament);GO:0005882(intermediate filament)","03013(RNA transport);03015(mRNA surveillance pathway);03015(mRNA surveillance pathway)","K13114","NA","pinin, desmosome associated protein [Source:HGNC Symbol;Acc:HGNC:9162]",{"v":8.12597554844085,"d":"8.13"},{"v":1.19525024779814,"d":"1.20"},{"v":6.79855583666292,"d":"6.80"},{"v":2.76522831863381,"d":"2.77"},{"v":0.000326374751223561,"d":"0.00"},{"v":0.033840982017493,"d":"0.03"},"up","yes"]
["ENSG00000089916","GPATCH2L","ENST00000261530;ENST00000553588;ENST00000554799;ENST00000554375;ENST00000621494;ENST00000556372;ENST00000556663;ENST00000312858;ENST00000554125;ENST00000557207;ENST00000557542;ENST00000556675","GO:0005515(protein binding);GO:0005515(protein binding)","NA","NA","NA","G-patch domain containing 2 like [Source:HGNC Symbol;Acc:HGNC:20210]",{"v":2.62704553527084,"d":"2.63"},{"v":0.388790205439578,"d":"0.39"},{"v":6.75697458041831,"d":"6.76"},{"v":2.75637742774468,"d":"2.76"},{"v":0.000339710783776317,"d":"0.00"},{"v":0.0349120471857909,"d":"0.03"},"up","yes"]
["MSTRG.6219","MAP1LC3B","ENST00000268607;ENST00000562778;ENST00000570189;ENST00000564844;ENST00000564638;ENST00000565788;ENST00000561823","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0005874(microtubule);GO:0006914(autophagy);GO:0031410(cytoplasmic vesicle);GO:0005829(cytosol);GO:0000421(autophagosome membrane);GO:0061024(membrane organization);GO:0005930(axoneme);GO:0000045(autophagosome assembly);GO:0006995(cellular response to nitrogen starvation);GO:0012505(endomembrane system);GO:0009267(cellular response to starvation);GO:0031625(ubiquitin protein ligase binding);GO:0005776(autophagosome);GO:0031090(organelle membrane);GO:0005739(mitochondrion);GO:0005622(intracellular);GO:0016236(macroautophagy);GO:0097352(autophagosome maturation);GO:0000422(mitophagy);GO:0000422(mitophagy)","04216(Ferroptosis);04216(Ferroptosis)","K10435","NA","microtubule associated protein 1 light chain 3 beta [Source:HGNC Symbol;Acc:HGNC:13352]",{"v":3.23871172106155,"d":"3.24"},{"v":14.8435224123847,"d":"14.84"},{"v":0.21819024023296,"d":"0.22"},{"v":-2.19634152430932,"d":"-2.20"},{"v":0.000358538249416826,"d":"0.00"},{"v":0.0365237253550666,"d":"0.04"},"down","yes"]
["ENSG00000188158","NHS","ENST00000615422;ENST00000398097;ENST00000380060;ENST00000485305","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005794(Golgi apparatus);GO:0005886(plasma membrane);GO:0030054(cell junction);GO:0042995(cell projection);GO:0016604(nuclear body);GO:0005925(focal adhesion);GO:0005923(bicellular tight junction);GO:0030027(lamellipodium);GO:0030154(cell differentiation);GO:0016324(apical plasma membrane);GO:0002088(lens development in camera-type eye);GO:0002088(lens development in camera-type eye)","NA","NA","NA","NHS actin remodeling regulator [Source:HGNC Symbol;Acc:HGNC:7820]",{"v":0.92755085395358,"d":"0.93"},{"v":0.134573740165224,"d":"0.13"},{"v":6.89251003066996,"d":"6.89"},{"v":2.78502946179111,"d":"2.79"},{"v":0.000364495875227528,"d":"0.00"},{"v":0.0368077443392807,"d":"0.04"},"up","yes"]
["MSTRG.839","NOTCH2","ENST00000256646;ENST00000602566;ENST00000478864;ENST00000479412;ENST00000579475;ENST00000489731;ENST00000493703","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005654(nucleoplasm);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0005509(calcium ion binding);GO:0005886(plasma membrane);GO:0007275(multicellular organism development);GO:0030522(intracellular receptor signaling pathway);GO:0030154(cell differentiation);GO:0006915(apoptotic process);GO:0007399(nervous system development);GO:0007219(Notch signaling pathway);GO:0004872(receptor activity);GO:0005576(extracellular region);GO:0005887(integral component of plasma membrane);GO:0005515(protein binding);GO:0050793(regulation of developmental process);GO:0005789(endoplasmic reticulum membrane);GO:0008285(negative regulation of cell proliferation);GO:0007050(cell cycle arrest);GO:0043066(negative regulation of apoptotic process);GO:0009986(cell surface);GO:0006367(transcription initiation from RNA polymerase II promoter);GO:0000139(Golgi membrane);GO:0001709(cell fate determination);GO:0002315(marginal zone B cell differentiation);GO:0030097(hemopoiesis);GO:0009887(animal organ morphogenesis);GO:0043235(receptor complex);GO:0016049(cell growth);GO:0046579(positive regulation of Ras protein signal transduction);GO:0019827(stem cell population maintenance);GO:0003184(pulmonary valve morphogenesis);GO:0046849(bone remodeling);GO:0061314(Notch signaling involved in heart development);GO:0060413(atrial septum morphogenesis);GO:0038049(transcription factor activity, ligand-activated RNA polymerase II transcription factor binding);GO:0038049(transcription factor activity, ligand-activated RNA polymerase II transcription factor binding)","04330(Notch signaling pathway);04658(Th1 and Th2 cell differentiation);04919(Thyroid hormone signaling pathway);05200(Pathways in cancer);05206(MicroRNAs in cancer);05224(Breast cancer);05165(Human papillomavirus infection);01522(Endocrine resistance);01522(Endocrine resistance)","K20994","NA","notch 2 [Source:HGNC Symbol;Acc:HGNC:7882]",{"v":21.8696054402927,"d":"21.87"},{"v":3.31830251347653,"d":"3.32"},{"v":6.59060026970847,"d":"6.59"},{"v":2.72040987140823,"d":"2.72"},{"v":0.000375074459429533,"d":"0.00"},{"v":0.0375494801496135,"d":"0.04"},"up","yes"]
["ENSG00000175087","PDIK1L","ENST00000374269;ENST00000444713;ENST00000619836;ENST00000374271","GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0005515(protein binding);GO:0005515(protein binding)","NA","NA","NA","PDLIM1 interacting kinase 1 like [Source:HGNC Symbol;Acc:HGNC:18981]",{"v":0.192842796251378,"d":"0.19"},{"v":0.964665874531422,"d":"0.96"},{"v":0.19990631092351,"d":"0.20"},{"v":-2.32260407706028,"d":"-2.32"},{"v":0.000387477525339973,"d":"0.00"},{"v":0.0381549933025236,"d":"0.04"},"down","yes"]
["MSTRG.8788","AAK1","ENST00000606389;ENST00000409085;ENST00000623317;ENST00000471775;ENST00000470281;ENST00000406297;ENST00000489327;ENST00000624900;ENST00000409068;ENST00000492192;ENST00000495239;ENST00000495836","GO:0004672(protein kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0016020(membrane);GO:0000166(nucleotide binding);GO:0004674(protein serine/threonine kinase activity);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0005905(clathrin-coated pit);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0006897(endocytosis);GO:0031252(cell leading edge);GO:0050821(protein stabilization);GO:0061024(membrane organization);GO:0030136(clathrin-coated vesicle);GO:0046777(protein autophosphorylation);GO:0005112(Notch binding);GO:0045747(positive regulation of Notch signaling pathway);GO:0032880(regulation of protein localization);GO:0019897(extrinsic component of plasma membrane);GO:2000369(regulation of clathrin-dependent endocytosis);GO:0043195(terminal bouton);GO:0035612(AP-2 adaptor complex binding);GO:0035612(AP-2 adaptor complex binding)","NA","NA","NA","AP2 associated kinase 1 [Source:HGNC Symbol;Acc:HGNC:19679]",{"v":3.22029346789224,"d":"3.22"},{"v":0.489117513046425,"d":"0.49"},{"v":6.58388502148477,"d":"6.58"},{"v":2.71893914129081,"d":"2.72"},{"v":0.000387693895608179,"d":"0.00"},{"v":0.0381549933025236,"d":"0.04"},"up","yes"]
["MSTRG.12547","CPEB4","MSTRG.12547.2;ENST00000518141;ENST00000265085;ENST00000519467;ENST00000519835;ENST00000519152;ENST00000520867;ENST00000334035","GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0046872(metal ion binding);GO:0005783(endoplasmic reticulum);GO:0005886(plasma membrane);GO:0042995(cell projection);GO:0005515(protein binding);GO:0003730(mRNA 3'-UTR binding);GO:0045182(translation regulator activity);GO:0006417(regulation of translation);GO:0048471(perinuclear region of cytoplasm);GO:0030054(cell junction);GO:0045202(synapse);GO:0045211(postsynaptic membrane);GO:0030425(dendrite);GO:0071230(cellular response to amino acid stimulus);GO:0030424(axon);GO:0030426(growth cone);GO:0014069(postsynaptic density);GO:0043197(dendritic spine);GO:0000900(translation repressor activity, nucleic acid binding);GO:0008135(translation factor activity, RNA binding);GO:0043022(ribosome binding);GO:2000766(negative regulation of cytoplasmic translation);GO:0043005(neuron projection);GO:1990124(messenger ribonucleoprotein complex);GO:0043524(negative regulation of neuron apoptotic process);GO:0002931(response to ischemia);GO:0042149(cellular response to glucose starvation);GO:0035235(ionotropic glutamate receptor signaling pathway);GO:0006412(translation);GO:0036294(cellular response to decreased oxygen levels);GO:0036294(cellular response to decreased oxygen levels)","04114(Oocyte meiosis);04914(Progesterone-mediated oocyte maturation);04914(Progesterone-mediated oocyte maturation)","K02602","NA","cytoplasmic polyadenylation element binding protein 4 [Source:HGNC Symbol;Acc:HGNC:21747]",{"v":3.71655278076324,"d":"3.72"},{"v":0.563051125389408,"d":"0.56"},{"v":6.60073768291087,"d":"6.60"},{"v":2.72262726568411,"d":"2.72"},{"v":0.000408382615765364,"d":"0.00"},{"v":0.0398533387973376,"d":"0.04"},"up","yes"]
["ENSG00000154079","SDHAF4","ENST00000370474;ENST00000468640","GO:0008177(succinate dehydrogenase (ubiquinone) activity);GO:0005739(mitochondrion);GO:0005759(mitochondrial matrix);GO:0003674(molecular_function);GO:0005575(cellular_component);GO:0034553(mitochondrial respiratory chain complex II assembly);GO:0005749(mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone));GO:0045333(cellular respiration);GO:0003407(neural retina development);GO:0045087(innate immune response);GO:0097032(mitochondrial respiratory chain complex II biogenesis);GO:0097032(mitochondrial respiratory chain complex II biogenesis)","NA","NA","NA","succinate dehydrogenase complex assembly factor 4 [Source:HGNC Symbol;Acc:HGNC:20957]",{"v":0.538132725,"d":"0.54"},{"v":2.620422775,"d":"2.62"},{"v":0.205361031866318,"d":"0.21"},{"v":-2.28376564481251,"d":"-2.28"},{"v":0.000414012803632334,"d":"0.00"},{"v":0.0399198675190728,"d":"0.04"},"down","yes"]
["ENSG00000167766","ZNF83","ENST00000541777;ENST00000595171;ENST00000600457;ENST00000601237;ENST00000597161;ENST00000598190;ENST00000596440;ENST00000598536;ENST00000536937;ENST00000600714;ENST00000601257;ENST00000594682;ENST00000597597;ENST00000595939","GO:0003676(nucleic acid binding);GO:0006355(regulation of transcription, DNA-templated);GO:0005622(intracellular);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0005515(protein binding);GO:0005515(protein binding)","NA","NA","NA","zinc finger protein 83 [Source:HGNC Symbol;Acc:HGNC:13158]",{"v":0.431577278898854,"d":"0.43"},{"v":2.00405131464873,"d":"2.00"},{"v":0.215352409264281,"d":"0.22"},{"v":-2.21522863100489,"d":"-2.22"},{"v":0.000415939375683097,"d":"0.00"},{"v":0.0399198675190728,"d":"0.04"},"down","yes"]
["ENSG00000140443","IGF1R","ENST00000268035;ENST00000559582;ENST00000560144;ENST00000560277;ENST00000560343;ENST00000558762;ENST00000561049;ENST00000559925;ENST00000558751;ENST00000557873","GO:0030335(positive regulation of cell migration);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0004713(protein tyrosine kinase activity);GO:0007169(transmembrane receptor protein tyrosine kinase signaling pathway);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0004714(transmembrane receptor protein tyrosine kinase activity);GO:0046777(protein autophosphorylation);GO:0042802(identical protein binding);GO:0005887(integral component of plasma membrane);GO:0043548(phosphatidylinositol 3-kinase binding);GO:0043560(insulin receptor substrate binding);GO:0043066(negative regulation of apoptotic process);GO:0007165(signal transduction);GO:0043235(receptor complex);GO:0006955(immune response);GO:0051262(protein tetramerization);GO:0008284(positive regulation of cell proliferation);GO:0046328(regulation of JNK cascade);GO:0045740(positive regulation of DNA replication);GO:0005158(insulin receptor binding);GO:0008286(insulin receptor signaling pathway);GO:0014065(phosphatidylinositol 3-kinase signaling);GO:0048009(insulin-like growth factor receptor signaling pathway);GO:0048015(phosphatidylinositol-mediated signaling);GO:0035867(alphav-beta3 integrin-IGF-1-IGF1R complex);GO:0031994(insulin-like growth factor I binding);GO:0043559(insulin binding);GO:0005010(insulin-like growth factor-activated receptor activity);GO:0005520(insulin-like growth factor binding);GO:0038083(peptidyl-tyrosine autophosphorylation);GO:0051389(inactivation of MAPKK activity);GO:0043231(intracellular membrane-bounded organelle);GO:0018108(peptidyl-tyrosine phosphorylation);GO:0018108(peptidyl-tyrosine phosphorylation)","04014(Ras signaling pathway);04015(Rap1 signaling pathway);04010(MAPK signaling pathway);04066(HIF-1 signaling pathway);04068(FoxO signaling pathway);04151(PI3K-Akt signaling pathway);04152(AMPK signaling pathway);04150(mTOR signaling pathway);04144(Endocytosis);04140(Autophagy - animal);04114(Oocyte meiosis);04510(Focal adhesion);04520(Adherens junction);04550(Signaling pathways regulating pluripotency of stem cells);04913(Ovarian Steroidogenesis);04914(Progesterone-mediated oocyte maturation);04730(Long-term depression);04211(Longevity regulating pathway - mammal);04213(Longevity regulating pathway - multiple species);05200(Pathways in cancer);05202(Transcriptional misregulation in cancers);05205(Proteoglycans in cancer);05225(Hepatocellular carcinoma);05214(Glioma);05218(Melanoma);05215(Prostate cancer);05224(Breast cancer);01521(EGFR tyrosine kinase inhibitor resistance);01522(Endocrine resistance);01522(Endocrine resistance)","K05087","EC:2.7.10.1","insulin like growth factor 1 receptor [Source:HGNC Symbol;Acc:HGNC:5465]",{"v":5.83859541157747,"d":"5.84"},{"v":0.904297299800133,"d":"0.90"},{"v":6.45649988434988,"d":"6.46"},{"v":2.69075228133467,"d":"2.69"},{"v":4.43923722351838E-4,"d":"0.00"},{"v":0.0421557960577355,"d":"0.04"},"up","yes"]
["ENSG00000198482","ZNF808","ENST00000359798;ENST00000487863;ENST00000461321;ENST00000486474;ENST00000465448;ENST00000461779","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0005622(intracellular);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding)","NA","NA","NA","zinc finger protein 808 [Source:HGNC Symbol;Acc:HGNC:33230]",{"v":1.99238607827476,"d":"1.99"},{"v":0.298218736621406,"d":"0.30"},{"v":6.68095539819864,"d":"6.68"},{"v":2.74005442750239,"d":"2.74"},{"v":0.000446496419108023,"d":"0.00"},{"v":0.0421557960577355,"d":"0.04"},"up","yes"]
["MSTRG.13004","CCDC167","ENST00000373408","GO:0016020(membrane);GO:0016021(integral component of membrane)","NA","NA","NA","coiled-coil domain containing 167 [Source:HGNC Symbol;Acc:HGNC:21239]",{"v":1.801415,"d":"1.80"},{"v":8.412321,"d":"8.41"},{"v":0.214140069072495,"d":"0.21"},{"v":-2.22337332231439,"d":"-2.22"},{"v":0.00045849261337974,"d":"0.00"},{"v":0.0429393122514429,"d":"0.04"},"down","yes"]
["ENSG00000118596","SLC16A7","ENST00000547379;ENST00000548444;ENST00000261187;ENST00000549033;ENST00000551877;ENST00000549465;ENST00000546459","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0055085(transmembrane transport);GO:0005887(integral component of plasma membrane);GO:0015293(symporter activity);GO:0005886(plasma membrane);GO:0008028(monocarboxylic acid transmembrane transporter activity);GO:0015718(monocarboxylic acid transport);GO:1901475(pyruvate transmembrane transport);GO:0005477(pyruvate secondary active transmembrane transporter activity);GO:0015129(lactate transmembrane transporter activity);GO:0050833(pyruvate transmembrane transporter activity);GO:0035873(lactate transmembrane transport);GO:0035873(lactate transmembrane transport)","NA","NA","NA","solute carrier family 16 member 7 [Source:HGNC Symbol;Acc:HGNC:10928]",{"v":1.10123801339188,"d":"1.10"},{"v":0.167283072081961,"d":"0.17"},{"v":6.58308099968611,"d":"6.58"},{"v":2.7187629491048,"d":"2.72"},{"v":0.000463463921198565,"d":"0.00"},{"v":0.0430576521350314,"d":"0.04"},"up","yes"]
["MSTRG.286","ARID1A","MSTRG.286.2;ENST00000324856;ENST00000636422;ENST00000636110;ENST00000430799;ENST00000524572;ENST00000374152;ENST00000466382;ENST00000636072;ENST00000637788;ENST00000457599;ENST00000636958;ENST00000636794;ENST00000430291;ENST00000615191;ENST00000636219;ENST00000532781","GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0003677(DNA binding);GO:0006338(chromatin remodeling);GO:0090544(BAF-type complex);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0016569(covalent chromatin modification);GO:0005515(protein binding);GO:0007399(nervous system development);GO:0045893(positive regulation of transcription, DNA-templated);GO:0003713(transcription coactivator activity);GO:0000790(nuclear chromatin);GO:0030521(androgen receptor signaling pathway);GO:0016922(ligand-dependent nuclear receptor binding);GO:0031491(nucleosome binding);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0001704(formation of primary germ layer);GO:0001843(neural tube closure);GO:0003205(cardiac chamber development);GO:0003408(optic cup formation involved in camera-type eye development);GO:0006325(chromatin organization);GO:0006337(nucleosome disassembly);GO:0006344(maintenance of chromatin silencing);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0007369(gastrulation);GO:0007566(embryo implantation);GO:0019827(stem cell population maintenance);GO:0030520(intracellular estrogen receptor signaling pathway);GO:0030900(forebrain development);GO:0042766(nucleosome mobilization);GO:0042921(glucocorticoid receptor signaling pathway);GO:0043044(ATP-dependent chromatin remodeling);GO:0048096(chromatin-mediated maintenance of transcription);GO:0055007(cardiac muscle cell differentiation);GO:0060674(placenta blood vessel development);GO:1901998(toxin transport);GO:0016514(SWI/SNF complex);GO:0071564(npBAF complex);GO:0071565(nBAF complex);GO:0071565(nBAF complex)","05225(Hepatocellular carcinoma);05225(Hepatocellular carcinoma)","K11653","NA","AT-rich interaction domain 1A [Source:HGNC Symbol;Acc:HGNC:11110]",{"v":9.36803518028469,"d":"9.37"},{"v":1.46569426588073,"d":"1.47"},{"v":6.39153430449936,"d":"6.39"},{"v":2.67616229545849,"d":"2.68"},{"v":0.000476141890992712,"d":"0.00"},{"v":0.0438844109531617,"d":"0.04"},"up","yes"]
["MSTRG.8258","ZC3H4","MSTRG.8258.4;ENST00000601973;ENST00000595341;ENST00000253048;ENST00000594019;ENST00000597069","GO:0003723(RNA binding);GO:0046872(metal ion binding);GO:0046872(metal ion binding)","NA","NA","NA","zinc finger CCCH-type containing 4 [Source:HGNC Symbol;Acc:HGNC:17808]",{"v":5.60288673343535,"d":"5.60"},{"v":0.872892493649579,"d":"0.87"},{"v":6.41875921055247,"d":"6.42"},{"v":2.68229444161721,"d":"2.68"},{"v":0.000485730036890515,"d":"0.00"},{"v":0.0439821917788902,"d":"0.04"},"up","yes"]
["MSTRG.13517","EEF1A1P6","ENST00000434005","NA","NA","NA","NA","eukaryotic translation elongation factor 1 alpha 1 pseudogene 6 [Source:HGNC Symbol;Acc:HGNC:3201]",{"v":2.852019,"d":"2.85"},{"v":12.693496,"d":"12.69"},{"v":0.224683491451055,"d":"0.22"},{"v":-2.15403396804039,"d":"-2.15"},{"v":4.86531381914835E-4,"d":"0.00"},{"v":0.0439821917788902,"d":"0.04"},"down","yes"]
["ENSG00000055609","KMT2C","ENST00000558084;ENST00000360104;ENST00000418673;ENST00000452749;ENST00000485241;ENST00000262189;ENST00000489110;ENST00000355193;ENST00000424877;ENST00000473186;ENST00000418061","GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006355(regulation of transcription, DNA-templated);GO:0003723(RNA binding);GO:0008168(methyltransferase activity);GO:0016740(transferase activity);GO:0032259(methylation);GO:0006351(transcription, DNA-templated);GO:0016569(covalent chromatin modification);GO:0003677(DNA binding);GO:0016746(transferase activity, transferring acyl groups);GO:0005515(protein binding);GO:0018024(histone-lysine N-methyltransferase activity);GO:0051568(histone H3-K4 methylation);GO:0034968(histone lysine methylation);GO:0005654(nucleoplasm);GO:0035097(histone methyltransferase complex);GO:0045652(regulation of megakaryocyte differentiation);GO:0044666(MLL3/4 complex);GO:0042800(histone methyltransferase activity (H3-K4 specific));GO:0042800(histone methyltransferase activity (H3-K4 specific))","00310(Lysine degradation);00310(Lysine degradation)","K09188","EC:2.1.1.43","lysine methyltransferase 2C [Source:HGNC Symbol;Acc:HGNC:13726]",{"v":8.90964376633191,"d":"8.91"},{"v":1.40210940220742,"d":"1.40"},{"v":6.35445690065622,"d":"6.35"},{"v":2.66776882700647,"d":"2.67"},{"v":4.88564775637375E-4,"d":"0.00"},{"v":0.0439821917788902,"d":"0.04"},"up","yes"]
["MSTRG.12828","TUBB","ENST00000327892;ENST00000396389;ENST00000396384;ENST00000330914","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005525(GTP binding);GO:0000166(nucleotide binding);GO:0003924(GTPase activity);GO:0015630(microtubule cytoskeleton);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0005200(structural constituent of cytoskeleton);GO:0005874(microtubule);GO:0005576(extracellular region);GO:0007017(microtubule-based process);GO:0070062(extracellular exosome);GO:0000086(G2/M transition of mitotic cell cycle);GO:0010389(regulation of G2/M transition of mitotic cell cycle);GO:0097711(ciliary basal body docking);GO:0031012(extracellular matrix);GO:0043312(neutrophil degranulation);GO:0035578(azurophil granule lumen);GO:0036464(cytoplasmic ribonucleoprotein granule);GO:0006928(movement of cell or subcellular component);GO:0031625(ubiquitin protein ligase binding);GO:0042288(MHC class I protein binding);GO:0005198(structural molecule activity);GO:0019904(protein domain specific binding);GO:0032403(protein complex binding);GO:0032794(GTPase activating protein binding);GO:0009987(cellular process);GO:0030705(cytoskeleton-dependent intracellular transport);GO:0042267(natural killer cell mediated cytotoxicity);GO:0051225(spindle assembly);GO:0051301(cell division);GO:0005641(nuclear envelope lumen);GO:0043234(protein complex);GO:0044297(cell body);GO:0045121(membrane raft);GO:0007010(cytoskeleton organization);GO:0007010(cytoskeleton organization)","04145(Phagosome);04540(Gap junction);05130(Pathogenic Escherichia coli infection);05130(Pathogenic Escherichia coli infection)","K07375","NA","tubulin beta class I [Source:HGNC Symbol;Acc:HGNC:20778]",{"v":8.79286203989283,"d":"8.79"},{"v":37.9764988335814,"d":"37.98"},{"v":0.23153429910494,"d":"0.23"},{"v":-2.11070216713297,"d":"-2.11"},{"v":0.000536755494073907,"d":"0.00"},{"v":0.0477623735823598,"d":"0.05"},"down","yes"]
["ENSG00000184226","PCDH9","ENST00000544246;ENST00000456367;ENST00000377861;ENST00000377865","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005509(calcium ion binding);GO:0007155(cell adhesion);GO:0007156(homophilic cell adhesion via plasma membrane adhesion molecules);GO:0005886(plasma membrane);GO:0030900(forebrain development);GO:0030426(growth cone);GO:0044291(cell-cell contact zone);GO:0044291(cell-cell contact zone)","NA","NA","NA","protocadherin 9 [Source:HGNC Symbol;Acc:HGNC:8661]",{"v":0.174409915718718,"d":"0.17"},{"v":0.0258540564245088,"d":"0.03"},{"v":6.74594008982602,"d":"6.75"},{"v":2.75401950594947,"d":"2.75"},{"v":0.000538781618814186,"d":"0.00"},{"v":0.0477623735823598,"d":"0.05"},"up","yes"]
["ENSG00000127124","HIVEP3","ENST00000372584;ENST00000491442;ENST00000479350;ENST00000460604;ENST00000372583","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0007165(signal transduction);GO:0007275(multicellular organism development);GO:0043565(sequence-specific DNA binding);GO:0045893(positive regulation of transcription, DNA-templated);GO:0044212(transcription regulatory region DNA binding);GO:0006366(transcription from RNA polymerase II promoter);GO:0003677(DNA binding);GO:0035914(skeletal muscle cell differentiation);GO:0035914(skeletal muscle cell differentiation)","NA","NA","NA","human immunodeficiency virus type I enhancer binding protein 3 [Source:HGNC Symbol;Acc:HGNC:13561]",{"v":0.99279441946828,"d":"0.99"},{"v":0.154582256857505,"d":"0.15"},{"v":6.42243449960395,"d":"6.42"},{"v":2.68312027160668,"d":"2.68"},{"v":0.000567329211831177,"d":"0.00"},{"v":0.0499120767954202,"d":"0.05"},"up","yes"]
["MSTRG.12393","SLC35A4","ENST00000323146;ENST00000623481;ENST00000612662;ENST00000514199","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005794(Golgi apparatus);GO:0000139(Golgi membrane);GO:0008643(carbohydrate transport);GO:0005351(sugar:proton symporter activity);GO:0015992(proton transport);GO:0032056(positive regulation of translation in response to stress);GO:0032056(positive regulation of translation in response to stress)","NA","NA","NA","solute carrier family 35 member A4 [Source:HGNC Symbol;Acc:HGNC:20753]",{"v":0.857372075814069,"d":"0.86"},{"v":3.74135222744221,"d":"3.74"},{"v":0.229161015508079,"d":"0.23"},{"v":-2.12556645880675,"d":"-2.13"},{"v":0.00058219047537062,"d":"0.00"},{"v":0.0508344209810452,"d":"0.05"},"down","yes"]
["MSTRG.7220","SMIM5","ENST00000375215;ENST00000537494;ENST00000581115","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016021(integral component of membrane)","NA","NA","NA","small integral membrane protein 5 [Source:HGNC Symbol;Acc:HGNC:40030]",{"v":0.615625392222005,"d":"0.62"},{"v":2.68241760406488,"d":"2.68"},{"v":0.229503933798041,"d":"0.23"},{"v":-2.12340921261087,"d":"-2.12"},{"v":0.000604071281619491,"d":"0.00"},{"v":0.0523513417421429,"d":"0.05"},"down","yes"]
["MSTRG.12697","RNF144B","ENST00000259939;ENST00000486622","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0046872(metal ion binding);GO:0016740(transferase activity);GO:0016567(protein ubiquitination);GO:0004842(ubiquitin-protein transferase activity);GO:0005739(mitochondrion);GO:0005515(protein binding);GO:0006915(apoptotic process);GO:0031966(mitochondrial membrane);GO:0000151(ubiquitin ligase complex);GO:0061630(ubiquitin protein ligase activity);GO:0005829(cytosol);GO:0000209(protein polyubiquitination);GO:0042787(protein ubiquitination involved in ubiquitin-dependent protein catabolic process);GO:0043066(negative regulation of apoptotic process);GO:0032436(positive regulation of proteasomal ubiquitin-dependent protein catabolic process);GO:0031624(ubiquitin conjugating enzyme binding);GO:0031624(ubiquitin conjugating enzyme binding)","NA","NA","NA","ring finger protein 144B [Source:HGNC Symbol;Acc:HGNC:21578]",{"v":9.11015100231884,"d":"9.11"},{"v":1.47149487149758,"d":"1.47"},{"v":6.19108579906038,"d":"6.19"},{"v":2.63019245298503,"d":"2.63"},{"v":0.000613695429373917,"d":"0.00"},{"v":0.0524927435087342,"d":"0.05"},"up","yes"]
["MSTRG.1466","EGLN1","ENST00000366641;ENST00000476717;MSTRG.1466.1","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0005829(cytosol);GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0005506(iron ion binding);GO:0016705(oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen);GO:0031418(L-ascorbic acid binding);GO:0005515(protein binding);GO:0051213(dioxygenase activity);GO:0061418(regulation of transcription from RNA polymerase II promoter in response to hypoxia);GO:0019899(enzyme binding);GO:0045765(regulation of angiogenesis);GO:0001666(response to hypoxia);GO:0030821(negative regulation of cAMP catabolic process);GO:0051344(negative regulation of cyclic-nucleotide phosphodiesterase activity);GO:0032364(oxygen homeostasis);GO:0043433(negative regulation of sequence-specific DNA binding transcription factor activity);GO:0016706(oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors);GO:0031545(peptidyl-proline 4-dioxygenase activity);GO:0018401(peptidyl-proline hydroxylation to 4-hydroxy-L-proline);GO:0031543(peptidyl-proline dioxygenase activity);GO:0006879(cellular iron ion homeostasis);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0055008(cardiac muscle tissue morphogenesis);GO:0060347(heart trabecula formation);GO:0060412(ventricular septum morphogenesis);GO:0060711(labyrinthine layer development);GO:0071731(response to nitric oxide);GO:1901214(regulation of neuron death);GO:1901214(regulation of neuron death)","04066(HIF-1 signaling pathway);05200(Pathways in cancer);05211(Renal cell carcinoma);05211(Renal cell carcinoma)","K09592","EC:1.14.11.29","egl-9 family hypoxia inducible factor 1 [Source:HGNC Symbol;Acc:HGNC:1232]",{"v":19.7489725311122,"d":"19.75"},{"v":3.21103960080843,"d":"3.21"},{"v":6.15033602392823,"d":"6.15"},{"v":2.62066523432369,"d":"2.62"},{"v":0.000618452553205883,"d":"0.00"},{"v":0.0524927435087342,"d":"0.05"},"up","yes"]
["MSTRG.7611","RPS15","ENST00000593052;ENST00000592623;ENST00000592588;ENST00000589656;ENST00000586096;ENST00000592700;ENST00000586686;ENST00000591804;ENST00000233609;ENST00000585665;ENST00000591032;ENST00000617694;ENST00000586656","GO:0003723(RNA binding);GO:0030529(intracellular ribonucleoprotein complex);GO:0003735(structural constituent of ribosome);GO:0006412(translation);GO:0005840(ribosome);GO:0015935(small ribosomal subunit);GO:0005634(nucleus);GO:0016020(membrane);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0022627(cytosolic small ribosomal subunit);GO:0005654(nucleoplasm);GO:0005925(focal adhesion);GO:0006364(rRNA processing);GO:0042274(ribosomal small subunit biogenesis);GO:0000028(ribosomal small subunit assembly);GO:0005829(cytosol);GO:0006413(translational initiation);GO:0000184(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay);GO:0019083(viral transcription);GO:0001649(osteoblast differentiation);GO:0006614(SRP-dependent cotranslational protein targeting to membrane);GO:0000056(ribosomal small subunit export from nucleus);GO:0000056(ribosomal small subunit export from nucleus)","03010(Ribosome);03010(Ribosome)","K02958","NA","ribosomal protein S15 [Source:HGNC Symbol;Acc:HGNC:10388]",{"v":26.0275460018718,"d":"26.03"},{"v":110.05436632335,"d":"110.05"},{"v":0.236497168366773,"d":"0.24"},{"v":-2.08010518492806,"d":"-2.08"},{"v":0.000622610857519932,"d":"0.00"},{"v":0.0524927435087342,"d":"0.05"},"down","yes"]
["MSTRG.5589","CREBBP","ENST00000262367;ENST00000635899;ENST00000634839;ENST00000573517;ENST00000576720;ENST00000573672;ENST00000571826;ENST00000635753;ENST00000574740;ENST00000571763;ENST00000575237;ENST00000636002;ENST00000382070;ENST00000570939;ENST00000572569;ENST00000572134","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0005654(nucleoplasm);GO:0016740(transferase activity);GO:0003713(transcription coactivator activity);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0016746(transferase activity, transferring acyl groups);GO:0005515(protein binding);GO:0000123(histone acetyltransferase complex);GO:0007165(signal transduction);GO:0016604(nuclear body);GO:0048511(rhythmic process);GO:0004402(histone acetyltransferase activity);GO:0045893(positive regulation of transcription, DNA-templated);GO:0003712(transcription cofactor activity);GO:0016573(histone acetylation);GO:0031648(protein destabilization);GO:0002223(stimulatory C-type lectin receptor signaling pathway);GO:0061418(regulation of transcription from RNA polymerase II promoter in response to hypoxia);GO:0003682(chromatin binding);GO:0001666(response to hypoxia);GO:0016032(viral process);GO:0004871(signal transducer activity);GO:0008134(transcription factor binding);GO:0042981(regulation of apoptotic process);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:1904837(beta-catenin-TCF complex assembly);GO:0000790(nuclear chromatin);GO:0006367(transcription initiation from RNA polymerase II promoter);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0001085(RNA polymerase II transcription factor binding);GO:0006461(protein complex assembly);GO:0042592(homeostatic process);GO:0007219(Notch signaling pathway);GO:0042733(embryonic digit morphogenesis);GO:0001078(transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0001102(RNA polymerase II activating transcription factor binding);GO:0001191(transcriptional repressor activity, RNA polymerase II transcription factor binding);GO:0032481(positive regulation of type I interferon production);GO:0002039(p53 binding);GO:0019216(regulation of lipid metabolic process);GO:1900034(regulation of cellular response to heat);GO:0003684(damaged DNA binding);GO:0000987(core promoter proximal region sequence-specific DNA binding);GO:0034644(cellular response to UV);GO:0045637(regulation of myeloid cell differentiation);GO:0001105(RNA polymerase II transcription coactivator activity);GO:0016407(acetyltransferase activity);GO:0006473(protein acetylation);GO:0034212(peptide N-acetyltransferase activity);GO:0018076(N-terminal peptidyl-lysine acetylation);GO:0043426(MRF binding);GO:0008589(regulation of smoothened signaling pathway);GO:0008589(regulation of smoothened signaling pathway)","04310(Wnt signaling pathway);04330(Notch signaling pathway);04350(TGF-beta signaling pathway);04630(Jak-STAT signaling pathway);04066(HIF-1 signaling pathway);04068(FoxO signaling pathway);04024(cAMP signaling pathway);04110(Cell cycle);04520(Adherens junction);04922(Glucagon signaling pathway);04919(Thyroid hormone signaling pathway);04916(Melanogenesis);04720(Long-term potentiation);05200(Pathways in cancer);05206(MicroRNAs in cancer);05203(Viral carcinogenesis);05211(Renal cell carcinoma);05215(Prostate cancer);05016(Huntington's disease);05152(Tuberculosis);05166(HTLV-I infection);05164(Influenza A);05161(Hepatitis B);05168(Herpes simplex infection);05167(Kaposi's sarcoma-associated herpesvirus infection);05169(Epstein-Barr virus infection);05165(Human papillomavirus infection);05165(Human papillomavirus infection)","K04498","EC:2.3.1.48","CREB binding protein [Source:HGNC Symbol;Acc:HGNC:2348]",{"v":15.3190990504777,"d":"15.32"},{"v":2.49460805176865,"d":"2.49"},{"v":6.14088415196793,"d":"6.14"},{"v":2.61844638683792,"d":"2.62"},{"v":0.000623783570499037,"d":"0.00"},{"v":0.0524927435087342,"d":"0.05"},"up","yes"]
["MSTRG.12882","LSM2","ENST00000375661;ENST00000470083;ENST00000470086;ENST00000491421;ENST00000475835","GO:0003723(RNA binding);GO:0006397(mRNA processing);GO:0008380(RNA splicing);GO:0005634(nucleus);GO:0030529(intracellular ribonucleoprotein complex);GO:0005515(protein binding);GO:0005681(spliceosomal complex);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0000398(mRNA splicing, via spliceosome);GO:0000932(P-body);GO:0046540(U4/U6 x U5 tri-snRNP complex);GO:0017160(Ral GTPase binding);GO:0043928(exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay);GO:1990726(Lsm1-7-Pat1 complex);GO:0071013(catalytic step 2 spliceosome);GO:0071011(precatalytic spliceosome);GO:0017070(U6 snRNA binding);GO:0005688(U6 snRNP);GO:0005688(U6 snRNP)","03040(Spliceosome);03018(RNA degradation);03018(RNA degradation)","K12621","NA","LSM2 homolog, U6 small nuclear RNA and mRNA degradation associated [Source:HGNC Symbol;Acc:HGNC:13940]",{"v":2.68357984215413,"d":"2.68"},{"v":11.6068492219127,"d":"11.61"},{"v":0.231206573881202,"d":"0.23"},{"v":-2.11274567641305,"d":"-2.11"},{"v":0.000632199131006043,"d":"0.00"},{"v":0.0525309772337489,"d":"0.05"},"down","yes"]
["MSTRG.4055","GPR18","ENST00000397470;ENST00000397473;ENST00000416594","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0004930(G-protein coupled receptor activity);GO:0007186(G-protein coupled receptor signaling pathway);GO:0005886(plasma membrane);GO:0004871(signal transducer activity);GO:0007165(signal transduction);GO:0030659(cytoplasmic vesicle membrane);GO:0031410(cytoplasmic vesicle);GO:0005887(integral component of plasma membrane);GO:0002300(CD8-positive, alpha-beta intraepithelial T cell differentiation);GO:0002305(CD8-positive, gamma-delta intraepithelial T cell differentiation);GO:0002689(negative regulation of leukocyte chemotaxis);GO:0032720(negative regulation of tumor necrosis factor production);GO:0035025(positive regulation of Rho protein signal transduction);GO:0051482(positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway);GO:0030217(T cell differentiation);GO:0030217(T cell differentiation)","NA","NA","NA","G protein-coupled receptor 18 [Source:HGNC Symbol;Acc:HGNC:4472]",{"v":1.83868313836478,"d":"1.84"},{"v":7.89532853773585,"d":"7.90"},{"v":0.232882410095636,"d":"0.23"},{"v":-2.10232641981323,"d":"-2.10"},{"v":0.000633284837055442,"d":"0.00"},{"v":0.0525309772337489,"d":"0.05"},"down","yes"]
["MSTRG.1487","ZBTB18","ENST00000358704;ENST00000622512","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0005654(nucleoplasm);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0045171(intercellular bridge);GO:0015630(microtubule cytoskeleton);GO:0005515(protein binding);GO:0007275(multicellular organism development);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0043565(sequence-specific DNA binding);GO:0045892(negative regulation of transcription, DNA-templated);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0007519(skeletal muscle tissue development);GO:0000228(nuclear chromosome);GO:0000228(nuclear chromosome)","NA","NA","NA","zinc finger and BTB domain containing 18 [Source:HGNC Symbol;Acc:HGNC:13030]",{"v":22.5374796682028,"d":"22.54"},{"v":3.72654053072197,"d":"3.73"},{"v":6.04782894011257,"d":"6.05"},{"v":2.59641733421154,"d":"2.60"},{"v":0.000701509952413798,"d":"0.00"},{"v":0.0577775537402939,"d":"0.06"},"up","yes"]
["MSTRG.14099","TRBV19","ENST00000390393","NA","NA","NA","NA","T-cell receptor beta variable 19 [Source:HGNC Symbol;Acc:HGNC:12194]",{"v":2.129381,"d":"2.13"},{"v":9.426707,"d":"9.43"},{"v":0.225888107055836,"d":"0.23"},{"v":-2.14631977963772,"d":"-2.15"},{"v":0.000711547424633487,"d":"0.00"},{"v":0.0581915510018922,"d":"0.06"},"down","yes"]
["MSTRG.11100","TRAT1","ENST00000295756;ENST00000478830;ENST00000426646;ENST00000493604","GO:0005622(intracellular);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005886(plasma membrane);GO:0002376(immune system process);GO:0002250(adaptive immune response);GO:0046854(phosphatidylinositol phosphorylation);GO:0050852(T cell receptor signaling pathway);GO:0005887(integral component of plasma membrane);GO:0007165(signal transduction);GO:0046934(phosphatidylinositol-4,5-bisphosphate 3-kinase activity);GO:0014066(regulation of phosphatidylinositol 3-kinase signaling);GO:0038111(interleukin-7-mediated signaling pathway);GO:0048015(phosphatidylinositol-mediated signaling);GO:0006968(cellular defense response);GO:0042101(T cell receptor complex);GO:0005068(transmembrane receptor protein tyrosine kinase adaptor activity);GO:0001920(negative regulation of receptor recycling);GO:0007169(transmembrane receptor protein tyrosine kinase signaling pathway);GO:0050850(positive regulation of calcium-mediated signaling);GO:0050862(positive regulation of T cell receptor signaling pathway);GO:0051051(negative regulation of transport);GO:0051051(negative regulation of transport)","NA","NA","NA","T-cell receptor associated transmembrane adaptor 1 [Source:HGNC Symbol;Acc:HGNC:30698]",{"v":4.8551289193038,"d":"4.86"},{"v":20.2097556823576,"d":"20.21"},{"v":0.240236893291202,"d":"0.24"},{"v":-2.05747037148288,"d":"-2.06"},{"v":7.25320754604571E-4,"d":"0.00"},{"v":0.0586557801762734,"d":"0.06"},"down","yes"]
["MSTRG.923","GOLPH3L","ENST00000271732;ENST00000427665;ENST00000479757","GO:0016020(membrane);GO:0005794(Golgi apparatus);GO:0005515(protein binding);GO:0000139(Golgi membrane);GO:0008289(lipid binding);GO:0032580(Golgi cisterna membrane);GO:0005829(cytosol);GO:0070273(phosphatidylinositol-4-phosphate binding);GO:0005802(trans-Golgi network);GO:0043001(Golgi to plasma membrane protein transport);GO:0050714(positive regulation of protein secretion);GO:0006890(retrograde vesicle-mediated transport, Golgi to ER);GO:0007030(Golgi organization);GO:0032588(trans-Golgi network membrane);GO:0048194(Golgi vesicle budding);GO:0031985(Golgi cisterna);GO:0031985(Golgi cisterna)","NA","NA","NA","golgi phosphoprotein 3 like [Source:HGNC Symbol;Acc:HGNC:24882]",{"v":0.767835399819766,"d":"0.77"},{"v":3.27434649203965,"d":"3.27"},{"v":0.234500350432207,"d":"0.23"},{"v":-2.09233801621311,"d":"-2.09"},{"v":0.000729667106735534,"d":"0.00"},{"v":0.0586557801762734,"d":"0.06"},"down","yes"]
["MSTRG.4548","FOS","MSTRG.4548.2;ENST00000303562;ENST00000555242;ENST00000555686;ENST00000556324;ENST00000554617;ENST00000555672;ENST00000557139;ENST00000555347;ENST00000535987;ENST00000554212","GO:0005634(nucleus);GO:0007179(transforming growth factor beta receptor signaling pathway);GO:0005737(cytoplasm);GO:0005654(nucleoplasm);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0005829(cytosol);GO:0005783(endoplasmic reticulum);GO:0005515(protein binding);GO:0005667(transcription factor complex);GO:0038095(Fc-epsilon receptor signaling pathway);GO:0006954(inflammatory response);GO:0045893(positive regulation of transcription, DNA-templated);GO:0070412(R-SMAD binding);GO:0006366(transcription from RNA polymerase II promoter);GO:0044212(transcription regulatory region DNA binding);GO:1902895(positive regulation of pri-miRNA transcription from RNA polymerase II promoter);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0046982(protein heterodimerization activity);GO:0008134(transcription factor binding);GO:0034614(cellular response to reactive oxygen species);GO:0071276(cellular response to cadmium ion);GO:0060395(SMAD protein signal transduction);GO:0032993(protein-DNA complex);GO:1901216(positive regulation of neuron death);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:0000979(RNA polymerase II core promoter sequence-specific DNA binding);GO:0001077(transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0001102(RNA polymerase II activating transcription factor binding);GO:0001190(transcriptional activator activity, RNA polymerase II transcription factor binding);GO:0003682(chromatin binding);GO:0003690(double-stranded DNA binding);GO:0043565(sequence-specific DNA binding);GO:0001661(conditioned taste aversion);GO:0006306(DNA methylation);GO:0007399(nervous system development);GO:0007565(female pregnancy);GO:0007568(aging);GO:0009409(response to cold);GO:0009416(response to light stimulus);GO:0009612(response to mechanical stimulus);GO:0009629(response to gravity);GO:0009636(response to toxic substance);GO:0014070(response to organic cyclic compound);GO:0030431(sleep);GO:0031668(cellular response to extracellular stimulus);GO:0032496(response to lipopolysaccharide);GO:0032570(response to progesterone);GO:0032870(cellular response to hormone stimulus);GO:0034097(response to cytokine);GO:0035902(response to immobilization stress);GO:0035914(skeletal muscle cell differentiation);GO:0035994(response to muscle stretch);GO:0042493(response to drug);GO:0045672(positive regulation of osteoclast differentiation);GO:0051090(regulation of sequence-specific DNA binding transcription factor activity);GO:0051412(response to corticosterone);GO:0051591(response to cAMP);GO:0071277(cellular response to calcium ion);GO:0016020(membrane);GO:0035976(transcription factor AP-1 complex);GO:0043005(neuron projection);GO:0043005(neuron projection)","04010(MAPK signaling pathway);04668(TNF signaling pathway);04024(cAMP signaling pathway);04210(Apoptosis);04620(Toll-like receptor signaling pathway);04660(T cell receptor signaling pathway);04658(Th1 and Th2 cell differentiation);04659(Th17 cell differentiation);04657(IL-17 signaling pathway);04662(B cell receptor signaling pathway);04915(Estrogen signaling pathway);04917(Prolactin signaling pathway);04921(Oxytocin signaling pathway);04926(Relaxin signaling pathway);04725(Cholinergic synapse);04728(Dopaminergic synapse);04380(Osteoclast differentiation);04713(Circadian entrainment);05200(Pathways in cancer);05231(Choline metabolism in cancer);05210(Colorectal cancer);05224(Breast cancer);05323(Rheumatoid arthritis);05031(Amphetamine addiction);05418(Fluid shear stress and atherosclerosis);05132(Salmonella infection);05133(Pertussis);05166(HTLV-I infection);05161(Hepatitis B);05168(Herpes simplex infection);05167(Kaposi's sarcoma-associated herpesvirus infection);05140(Leishmaniasis);05142(Chagas disease (American trypanosomiasis));01522(Endocrine resistance);01522(Endocrine resistance)","K04379","NA","Fos proto-oncogene, AP-1 transcription factor subunit [Source:HGNC Symbol;Acc:HGNC:3796]",{"v":37.9249594762018,"d":"37.92"},{"v":6.3092069526403,"d":"6.31"},{"v":6.01105016222852,"d":"6.01"},{"v":2.58761705940346,"d":"2.59"},{"v":0.000732376485452479,"d":"0.00"},{"v":0.0586557801762734,"d":"0.06"},"up","yes"]
["ENSG00000008086","CDKL5","ENST00000623535;ENST00000379996;ENST00000623610","GO:0005634(nucleus);GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0043547(positive regulation of GTPase activity);GO:0001764(neuron migration);GO:0044294(dendritic growth cone);GO:0032587(ruffle membrane);GO:0048365(Rac GTPase binding);GO:0045773(positive regulation of axon extension);GO:0046777(protein autophosphorylation);GO:0050773(regulation of dendrite development);GO:0050775(positive regulation of dendrite morphogenesis);GO:0032839(dendrite cytoplasm);GO:0060999(positive regulation of dendritic spine development);GO:0045202(synapse);GO:0048471(perinuclear region of cytoplasm);GO:0048471(perinuclear region of cytoplasm)","NA","NA","NA","cyclin dependent kinase like 5 [Source:HGNC Symbol;Acc:HGNC:11411]",{"v":0.834012447379209,"d":"0.83"},{"v":0.13550393341142,"d":"0.14"},{"v":6.15489474277446,"d":"6.15"},{"v":2.62173418483715,"d":"2.62"},{"v":0.000737766792221681,"d":"0.00"},{"v":0.0586827791648656,"d":"0.06"},"up","yes"]
["ENSG00000031081","ARHGAP31","ENST00000264245","GO:0007165(signal transduction);GO:0043547(positive regulation of GTPase activity);GO:0042995(cell projection);GO:0030054(cell junction);GO:0005096(GTPase activator activity);GO:0005925(focal adhesion);GO:0005829(cytosol);GO:0030027(lamellipodium);GO:0051056(regulation of small GTPase mediated signal transduction);GO:0007264(small GTPase mediated signal transduction);GO:0017124(SH3 domain binding)","NA","NA","NA","Rho GTPase activating protein 31 [Source:HGNC Symbol;Acc:HGNC:29216]",{"v":2.28829153868286,"d":"2.29"},{"v":0.377257085464621,"d":"0.38"},{"v":6.06560254756953,"d":"6.07"},{"v":2.60065096755715,"d":"2.60"},{"v":0.000763696055427199,"d":"0.00"},{"v":0.0599640260420038,"d":"0.06"},"up","yes"]
["MSTRG.6400","POLR2A","ENST00000617998;ENST00000576553;MSTRG.6400.9;ENST00000576718;ENST00000575547;ENST00000576952;ENST00000573603;ENST00000576114;ENST00000574158","GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0016740(transferase activity);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0006366(transcription from RNA polymerase II promoter);GO:0005665(DNA-directed RNA polymerase II, core complex);GO:0006351(transcription, DNA-templated);GO:0005515(protein binding);GO:0003899(DNA-directed 5'-3' RNA polymerase activity);GO:0016779(nucleotidyltransferase activity);GO:0005654(nucleoplasm);GO:0006368(transcription elongation from RNA polymerase II promoter);GO:0006370(7-methylguanosine mRNA capping);GO:0050434(positive regulation of viral transcription);GO:0006367(transcription initiation from RNA polymerase II promoter);GO:0042795(snRNA transcription from RNA polymerase II promoter);GO:0006353(DNA-templated transcription, termination);GO:0000398(mRNA splicing, via spliceosome);GO:0031625(ubiquitin protein ligase binding);GO:0060964(regulation of gene silencing by miRNA);GO:0006283(transcription-coupled nucleotide-excision repair);GO:0008543(fibroblast growth factor receptor signaling pathway);GO:0016070(RNA metabolic process);GO:0035019(somatic stem cell population maintenance);GO:0033120(positive regulation of RNA splicing);GO:0000974(Prp19 complex);GO:0001055(RNA polymerase II activity);GO:0003968(RNA-directed 5'-3' RNA polymerase activity);GO:0001172(transcription, RNA-templated);GO:0001172(transcription, RNA-templated)","NA","NA","NA","RNA polymerase II subunit A [Source:HGNC Symbol;Acc:HGNC:9187]",{"v":22.1231907483246,"d":"22.12"},{"v":3.70584510435615,"d":"3.71"},{"v":5.96980988825443,"d":"5.97"},{"v":2.57768498883686,"d":"2.58"},{"v":0.000764201830208953,"d":"0.00"},{"v":0.0599640260420038,"d":"0.06"},"up","yes"]
["MSTRG.10731","RPL15","ENST00000307839;ENST00000611050;ENST00000465786;ENST00000434031;ENST00000354811;ENST00000422218;ENST00000412097;ENST00000490223;ENST00000413699;ENST00000435882;ENST00000415719;ENST00000456530","GO:0005634(nucleus);GO:0003723(RNA binding);GO:0016020(membrane);GO:0006412(translation);GO:0030529(intracellular ribonucleoprotein complex);GO:0005622(intracellular);GO:0003735(structural constituent of ribosome);GO:0005840(ribosome);GO:0005515(protein binding);GO:0045471(response to ethanol);GO:0022625(cytosolic large ribosomal subunit);GO:0031672(A band);GO:0005829(cytosol);GO:0045296(cadherin binding);GO:0070062(extracellular exosome);GO:0002181(cytoplasmic translation);GO:0006413(translational initiation);GO:0006364(rRNA processing);GO:0000184(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay);GO:0019083(viral transcription);GO:0006614(SRP-dependent cotranslational protein targeting to membrane);GO:0006614(SRP-dependent cotranslational protein targeting to membrane)","03010(Ribosome);03010(Ribosome)","K02877","NA","ribosomal protein L15 [Source:HGNC Symbol;Acc:HGNC:10306]",{"v":29.7882411599265,"d":"29.79"},{"v":121.86889890962,"d":"121.87"},{"v":0.244428573872797,"d":"0.24"},{"v":-2.03251514780368,"d":"-2.03"},{"v":0.000778283443928928,"d":"0.00"},{"v":0.0605800290264392,"d":"0.06"},"down","yes"]
["MSTRG.3813","SETD1B","ENST00000619791;ENST00000604567;ENST00000542440","GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0005634(nucleus);GO:0016607(nuclear speck);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0008168(methyltransferase activity);GO:0016740(transferase activity);GO:0032259(methylation);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0016569(covalent chromatin modification);GO:0005694(chromosome);GO:0018024(histone-lysine N-methyltransferase activity);GO:0005515(protein binding);GO:0051568(histone H3-K4 methylation);GO:0042800(histone methyltransferase activity (H3-K4 specific));GO:0035097(histone methyltransferase complex);GO:0048188(Set1C/COMPASS complex);GO:0048188(Set1C/COMPASS complex)","00310(Lysine degradation);00310(Lysine degradation)","K11422","EC:2.1.1.43","SET domain containing 1B [Source:HGNC Symbol;Acc:HGNC:29187]",{"v":6.1079877859033,"d":"6.11"},{"v":1.02189861282175,"d":"1.02"},{"v":5.97709763891099,"d":"5.98"},{"v":2.5794451101087,"d":"2.58"},{"v":0.000782485520878832,"d":"0.00"},{"v":0.0605800290264392,"d":"0.06"},"up","yes"]
["MSTRG.3007","WNK1","MSTRG.3007.4;ENST00000535572;MSTRG.3007.1;MSTRG.3007.3;MSTRG.3007.2;ENST00000542543;ENST00000540360;ENST00000340908;ENST00000544965;ENST00000540885;ENST00000537603;ENST00000315939;ENST00000537687;ENST00000545285;ENST00000535698;ENST00000447667;ENST00000545055;ENST00000542424;ENST00000534872;ENST00000543065;ENST00000544559;ENST00000530271;ENST00000574564","GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0005829(cytosol);GO:0005737(cytoplasm);GO:0000166(nucleotide binding);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0006811(ion transport);GO:0005515(protein binding);GO:0004860(protein kinase inhibitor activity);GO:0071901(negative regulation of protein serine/threonine kinase activity);GO:0032147(activation of protein kinase activity);GO:0048666(neuron development);GO:0019902(phosphatase binding);GO:0010923(negative regulation of phosphatase activity);GO:0006469(negative regulation of protein kinase activity);GO:0035556(intracellular signal transduction);GO:0016020(membrane);GO:0019869(chloride channel inhibitor activity);GO:0002028(regulation of sodium ion transport);GO:0019901(protein kinase binding);GO:0018107(peptidyl-threonine phosphorylation);GO:0030295(protein kinase activator activity);GO:0023016(signal transduction by trans-phosphorylation);GO:0050794(regulation of cellular process);GO:0000287(magnesium ion binding);GO:0019870(potassium channel inhibitor activity);GO:0030291(protein serine/threonine kinase inhibitor activity);GO:0003084(positive regulation of systemic arterial blood pressure);GO:0033673(negative regulation of kinase activity);GO:0046777(protein autophosphorylation);GO:0071277(cellular response to calcium ion);GO:0090188(negative regulation of pancreatic juice secretion);GO:0090188(negative regulation of pancreatic juice secretion)","NA","NA","NA","WNK lysine deficient protein kinase 1 [Source:HGNC Symbol;Acc:HGNC:14540]",{"v":15.1901583072201,"d":"15.19"},{"v":2.55771652248766,"d":"2.56"},{"v":5.93895303629896,"d":"5.94"},{"v":2.57020862421318,"d":"2.57"},{"v":0.000793885730732828,"d":"0.00"},{"v":0.0610555959668896,"d":"0.06"},"up","yes"]
["MSTRG.2799","SRSF8","ENST00000587424;ENST00000638426","GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0006397(mRNA processing);GO:0008380(RNA splicing);GO:0005634(nucleus);GO:0016607(nuclear speck);GO:0005829(cytosol);GO:0005515(protein binding);GO:0005515(protein binding)","03040(Spliceosome);05168(Herpes simplex infection);05168(Herpes simplex infection)","K12891","NA","serine and arginine rich splicing factor 8 [Source:HGNC Symbol;Acc:HGNC:16988]",{"v":1.07571,"d":"1.08"},{"v":4.41845839721946,"d":"4.42"},{"v":0.243458216258627,"d":"0.24"},{"v":-2.03825390520431,"d":"-2.04"},{"v":0.000839525082690041,"d":"0.00"},{"v":0.0641408209557859,"d":"0.06"},"down","yes"]
["ENSG00000068650","ATP11A","ENST00000375645;ENST00000487903;ENST00000375630;ENST00000466946;ENST00000419631;ENST00000418678;ENST00000459011;ENST00000614170;ENST00000419448;ENST00000610419;ENST00000415301;ENST00000493489;ENST00000489577;ENST00000479193;ENST00000459908;ENST00000495930","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0043231(intracellular membrane-bounded organelle);GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0000287(magnesium ion binding);GO:0016787(hydrolase activity);GO:0005765(lysosomal membrane);GO:0005783(endoplasmic reticulum);GO:0005886(plasma membrane);GO:0006869(lipid transport);GO:0004012(phospholipid-translocating ATPase activity);GO:0015914(phospholipid transport);GO:0005515(protein binding);GO:0005768(endosome);GO:0005769(early endosome);GO:0055037(recycling endosome);GO:0043312(neutrophil degranulation);GO:0035579(specific granule membrane);GO:0070821(tertiary granule membrane);GO:0045332(phospholipid translocation);GO:0045332(phospholipid translocation)","NA","NA","NA","ATPase phospholipid transporting 11A [Source:HGNC Symbol;Acc:HGNC:13552]",{"v":4.16084989798296,"d":"4.16"},{"v":0.703010881671885,"d":"0.70"},{"v":5.91861378886159,"d":"5.92"},{"v":2.56525931874024,"d":"2.57"},{"v":0.000848513624554058,"d":"0.00"},{"v":0.064403847855858,"d":"0.06"},"up","yes"]
["ENSG00000171316","CHD7","ENST00000423902;ENST00000524602;ENST00000525508;ENST00000618450;ENST00000529472;ENST00000532149;ENST00000528280","GO:0005634(nucleus);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0016787(hydrolase activity);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0016569(covalent chromatin modification);GO:0004386(helicase activity);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0005730(nucleolus);GO:0006364(rRNA processing);GO:0016817(hydrolase activity, acting on acid anhydrides);GO:0003682(chromatin binding);GO:0060021(palate development);GO:0003007(heart morphogenesis);GO:0001501(skeletal system development);GO:0001701(in utero embryonic development);GO:0060041(retina development in camera-type eye);GO:0021545(cranial nerve development);GO:0048806(genitalia development);GO:0060324(face development);GO:0030217(T cell differentiation);GO:0060173(limb development);GO:0050890(cognition);GO:0007417(central nervous system development);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:1990841(promoter-specific chromatin binding);GO:0001568(blood vessel development);GO:0001974(blood vessel remodeling);GO:0003222(ventricular trabecula myocardium morphogenesis);GO:0003226(right ventricular compact myocardium morphogenesis);GO:0006338(chromatin remodeling);GO:0007512(adult heart development);GO:0007605(sensory perception of sound);GO:0007626(locomotory behavior);GO:0007628(adult walking behavior);GO:0008015(blood circulation);GO:0010880(regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum);GO:0021553(olfactory nerve development);GO:0021772(olfactory bulb development);GO:0030540(female genitalia development);GO:0035116(embryonic hindlimb morphogenesis);GO:0035904(aorta development);GO:0035909(aorta morphogenesis);GO:0036302(atrioventricular canal development);GO:0040018(positive regulation of multicellular organism growth);GO:0042048(olfactory behavior);GO:0042471(ear morphogenesis);GO:0042472(inner ear morphogenesis);GO:0043010(camera-type eye development);GO:0043584(nose development);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0048752(semicircular canal morphogenesis);GO:0048771(tissue remodeling);GO:0048844(artery morphogenesis);GO:0050767(regulation of neurogenesis);GO:0060123(regulation of growth hormone secretion);GO:0060384(innervation);GO:0060411(cardiac septum morphogenesis);GO:0060429(epithelium development);GO:0060429(epithelium development)","NA","NA","NA","chromodomain helicase DNA binding protein 7 [Source:HGNC Symbol;Acc:HGNC:20626]",{"v":2.0849966213638,"d":"2.08"},{"v":0.349876535390413,"d":"0.35"},{"v":5.95923536008849,"d":"5.96"},{"v":2.57512722783871,"d":"2.58"},{"v":0.000859619501698075,"d":"0.00"},{"v":0.0648231251507775,"d":"0.06"},"up","yes"]
["MSTRG.7187","TMEM104","ENST00000335464;ENST00000417024;ENST00000578764;ENST00000584171;ENST00000582330;ENST00000584246","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0003674(molecular_function);GO:0008150(biological_process);GO:0005575(cellular_component);GO:0005575(cellular_component)","NA","NA","NA","transmembrane protein 104 [Source:HGNC Symbol;Acc:HGNC:25984]",{"v":3.41808950150512,"d":"3.42"},{"v":0.574759564519366,"d":"0.57"},{"v":5.94699020687624,"d":"5.95"},{"v":2.57215969997799,"d":"2.57"},{"v":0.000927422988998191,"d":"0.00"},{"v":0.0694849236853935,"d":"0.07"},"up","yes"]
["MSTRG.2908","KMT2A","ENST00000389506;ENST00000534358;ENST00000531904;ENST00000533790;ENST00000527869;ENST00000420751;ENST00000534678;ENST00000528278;ENST00000525408;ENST00000527839;ENST00000392873;ENST00000529852","GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0005634(nucleus);GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0008168(methyltransferase activity);GO:0016740(transferase activity);GO:0032259(methylation);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0016569(covalent chromatin modification);GO:0003677(DNA binding);GO:0042803(protein homodimerization activity);GO:0005515(protein binding);GO:0048511(rhythmic process);GO:0006915(apoptotic process);GO:0018024(histone-lysine N-methyltransferase activity);GO:0045893(positive regulation of transcription, DNA-templated);GO:0042802(identical protein binding);GO:1902036(regulation of hematopoietic stem cell differentiation);GO:0044212(transcription regulatory region DNA binding);GO:0006366(transcription from RNA polymerase II promoter);GO:0071339(MLL1 complex);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0032922(circadian regulation of gene expression);GO:0001046(core promoter sequence-specific DNA binding);GO:0042800(histone methyltransferase activity (H3-K4 specific));GO:0045652(regulation of megakaryocyte differentiation);GO:0051568(histone H3-K4 methylation);GO:2000615(regulation of histone H3-K9 acetylation);GO:0006461(protein complex assembly);GO:0035097(histone methyltransferase complex);GO:0070577(lysine-acetylated histone binding);GO:0043984(histone H4-K16 acetylation);GO:0051571(positive regulation of histone H3-K4 methylation);GO:0035162(embryonic hemopoiesis);GO:0003680(AT DNA binding);GO:0032411(positive regulation of transporter activity);GO:0003682(chromatin binding);GO:0045322(unmethylated CpG binding);GO:0006306(DNA methylation);GO:0008285(negative regulation of cell proliferation);GO:0008542(visual learning);GO:0009416(response to light stimulus);GO:0009791(post-embryonic development);GO:0009952(anterior/posterior pattern specification);GO:0010468(regulation of gene expression);GO:0018026(peptidyl-lysine monomethylation);GO:0035640(exploration behavior);GO:0035864(response to potassium ion);GO:0044648(histone H3-K4 dimethylation);GO:0048172(regulation of short-term neuronal synaptic plasticity);GO:0048536(spleen development);GO:0048873(homeostasis of number of cells within a tissue);GO:0050890(cognition);GO:0051569(regulation of histone H3-K4 methylation);GO:0051899(membrane depolarization);GO:0060216(definitive hemopoiesis);GO:0071440(regulation of histone H3-K14 acetylation);GO:0080182(histone H3-K4 trimethylation);GO:1901674(regulation of histone H3-K27 acetylation);GO:2001040(positive regulation of cellular response to drug);GO:2001040(positive regulation of cellular response to drug)","00310(Lysine degradation);05202(Transcriptional misregulation in cancers);05202(Transcriptional misregulation in cancers)","K09186","EC:2.1.1.43","lysine methyltransferase 2A [Source:HGNC Symbol;Acc:HGNC:7132]",{"v":4.73503683088202,"d":"4.74"},{"v":0.816222193251673,"d":"0.82"},{"v":5.80116158324309,"d":"5.80"},{"v":2.53634180413625,"d":"2.54"},{"v":0.000940980023380923,"d":"0.00"},{"v":0.0700487244328376,"d":"0.07"},"up","yes"]
["ENSG00000198081","ZBTB14","ENST00000357006;ENST00000585253;ENST00000582388;ENST00000400143;ENST00000578327;ENST00000615385","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0005730(nucleolus);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0005515(protein binding);GO:0016235(aggresome);GO:0043565(sequence-specific DNA binding);GO:0044212(transcription regulatory region DNA binding);GO:0045892(negative regulation of transcription, DNA-templated);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:0001078(transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0003170(heart valve development);GO:0003279(cardiac septum development);GO:0060976(coronary vasculature development);GO:0060976(coronary vasculature development)","NA","NA","NA","zinc finger and BTB domain containing 14 [Source:HGNC Symbol;Acc:HGNC:12860]",{"v":0.26978397961165,"d":"0.27"},{"v":1.15156191601942,"d":"1.15"},{"v":0.234276573285965,"d":"0.23"},{"v":-2.09371539716911,"d":"-2.09"},{"v":0.00100662660153037,"d":"0.00"},{"v":0.073991709041427,"d":"0.07"},"down","yes"]
["MSTRG.4494","ZFP36L1","ENST00000439696;ENST00000555997;ENST00000557022;ENST00000336440;ENST00000557086;ENST00000553375","GO:0003723(RNA binding);GO:0006397(mRNA processing);GO:0006810(transport);GO:0051028(mRNA transport);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0003677(DNA binding);GO:0030529(intracellular ribonucleoprotein complex);GO:0005515(protein binding);GO:0007275(multicellular organism development);GO:0006355(regulation of transcription, DNA-templated);GO:0003729(mRNA binding);GO:0017091(AU-rich element binding);GO:0035925(mRNA 3'-UTR AU-rich region binding);GO:0000165(MAPK cascade);GO:0000288(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay);GO:0001570(vasculogenesis);GO:0003342(proepicardium development);GO:0006402(mRNA catabolic process);GO:0006417(regulation of translation);GO:0006915(apoptotic process);GO:0007507(heart development);GO:0008283(cell proliferation);GO:0021915(neural tube development);GO:0031086(nuclear-transcribed mRNA catabolic process, deadenylation-independent decay);GO:0033077(T cell differentiation in thymus);GO:0035264(multicellular organism growth);GO:0038066(p38MAPK cascade);GO:0043488(regulation of mRNA stability);GO:0043491(protein kinase B signaling);GO:0044344(cellular response to fibroblast growth factor stimulus);GO:0045577(regulation of B cell differentiation);GO:0045600(positive regulation of fat cell differentiation);GO:0045661(regulation of myoblast differentiation);GO:0048382(mesendoderm development);GO:0048568(embryonic organ development);GO:0060710(chorio-allantoic fusion);GO:0060712(spongiotrophoblast layer development);GO:0061158(3'-UTR-mediated mRNA destabilization);GO:0071320(cellular response to cAMP);GO:0071375(cellular response to peptide hormone stimulus);GO:0071472(cellular response to salt stress);GO:0072091(regulation of stem cell proliferation);GO:0097403(cellular response to raffinose);GO:1900153(positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay);GO:1901991(negative regulation of mitotic cell cycle phase transition);GO:0005829(cytosol);GO:0000932(P-body);GO:0071356(cellular response to tumor necrosis factor);GO:0070371(ERK1 and ERK2 cascade);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0014065(phosphatidylinositol 3-kinase signaling);GO:0071560(cellular response to transforming growth factor beta stimulus);GO:0032869(cellular response to insulin stimulus);GO:0071889(14-3-3 protein binding);GO:0071456(cellular response to hypoxia);GO:0031440(regulation of mRNA 3'-end processing);GO:0009611(response to wounding);GO:0071364(cellular response to epidermal growth factor stimulus);GO:0045616(regulation of keratinocyte differentiation);GO:0010468(regulation of gene expression);GO:0045647(negative regulation of erythrocyte differentiation);GO:0071385(cellular response to glucocorticoid stimulus);GO:1904628(cellular response to phorbol 13-acetate 12-myristate);GO:0010837(regulation of keratinocyte proliferation);GO:0045657(positive regulation of monocyte differentiation);GO:1902172(regulation of keratinocyte apoptotic process);GO:1904582(positive regulation of intracellular mRNA localization);GO:1904582(positive regulation of intracellular mRNA localization)","04218(Cellular senescence);04218(Cellular senescence)","K18753","NA","ZFP36 ring finger protein like 1 [Source:HGNC Symbol;Acc:HGNC:1107]",{"v":69.6048212821705,"d":"69.60"},{"v":12.1468867122093,"d":"12.15"},{"v":5.73026018364097,"d":"5.73"},{"v":2.51860064633412,"d":"2.52"},{"v":1.00668991893098E-3,"d":"0.00"},{"v":0.073991709041427,"d":"0.07"},"up","yes"]
["ENSG00000114744","COMMD2","ENST00000473414;ENST00000469896;ENST00000490008;ENST00000491617;ENST00000483146;ENST00000463077","GO:0005737(cytoplasm);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0005515(protein binding);GO:0005515(protein binding)","NA","NA","NA","COMM domain containing 2 [Source:HGNC Symbol;Acc:HGNC:24993]",{"v":0.896351451540502,"d":"0.90"},{"v":3.59435362844318,"d":"3.59"},{"v":0.249377647332029,"d":"0.25"},{"v":-2.00359593817386,"d":"-2.00"},{"v":0.001021350089305,"d":"0.00"},{"v":0.0743980307392123,"d":"0.07"},"down","yes"]
["MSTRG.15095","NOTCH1","ENST00000277541;ENST00000491649;ENST00000494783","GO:0008284(positive regulation of cell proliferation);GO:0010812(negative regulation of cell-substrate adhesion);GO:0060045(positive regulation of cardiac muscle cell proliferation);GO:0010718(positive regulation of epithelial to mesenchymal transition);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0060412(ventricular septum morphogenesis);GO:0030335(positive regulation of cell migration);GO:0005634(nucleus);GO:0030514(negative regulation of BMP signaling pathway);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0046872(metal ion binding);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0005509(calcium ion binding);GO:0007275(multicellular organism development);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0030154(cell differentiation);GO:0006955(immune response);GO:0007219(Notch signaling pathway);GO:0004872(receptor activity);GO:0045893(positive regulation of transcription, DNA-templated);GO:0005576(extracellular region);GO:0050793(regulation of developmental process);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0060271(cilium assembly);GO:0005789(endoplasmic reticulum membrane);GO:0001047(core promoter binding);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0008285(negative regulation of cell proliferation);GO:0005912(adherens junction);GO:0016324(apical plasma membrane);GO:0019899(enzyme binding);GO:0006367(transcription initiation from RNA polymerase II promoter);GO:0045892(negative regulation of transcription, DNA-templated);GO:0000139(Golgi membrane);GO:0001525(angiogenesis);GO:0001947(heart looping);GO:0007368(determination of left/right symmetry);GO:0045662(negative regulation of myoblast differentiation);GO:0097150(neuronal stem cell population maintenance);GO:0035148(tube formation);GO:0035924(cellular response to vascular endothelial growth factor stimulus);GO:0090051(negative regulation of cell migration involved in sprouting angiogenesis);GO:0004857(enzyme inhibitor activity);GO:0043086(negative regulation of catalytic activity);GO:0043235(receptor complex);GO:0055008(cardiac muscle tissue morphogenesis);GO:0001190(transcriptional activator activity, RNA polymerase II transcription factor binding);GO:0003184(pulmonary valve morphogenesis);GO:0030279(negative regulation of ossification);GO:0001837(epithelial to mesenchymal transition);GO:0003198(epithelial to mesenchymal transition involved in endocardial cushion formation);GO:0003273(cell migration involved in endocardial cushion formation);GO:2000811(negative regulation of anoikis);GO:0045668(negative regulation of osteoblast differentiation);GO:2000737(negative regulation of stem cell differentiation);GO:0061314(Notch signaling involved in heart development);GO:0060411(cardiac septum morphogenesis);GO:1901201(regulation of extracellular matrix assembly);GO:2001027(negative regulation of endothelial cell chemotaxis);GO:0010832(negative regulation of myotube differentiation);GO:0046427(positive regulation of JAK-STAT cascade);GO:0003203(endocardial cushion morphogenesis);GO:0048711(positive regulation of astrocyte differentiation);GO:0060317(cardiac epithelial to mesenchymal transition);GO:0003180(aortic valve morphogenesis);GO:0030513(positive regulation of BMP signaling pathway);GO:0003169(coronary vein morphogenesis);GO:0060948(cardiac vascular smooth muscle cell development);GO:0060982(coronary artery morphogenesis);GO:0003214(cardiac left ventricle morphogenesis);GO:0003208(cardiac ventricle morphogenesis);GO:0003209(cardiac atrium morphogenesis);GO:0003222(ventricular trabecula myocardium morphogenesis);GO:0003344(pericardium morphogenesis);GO:0061384(heart trabecula morphogenesis);GO:0050768(negative regulation of neurogenesis);GO:0060956(endocardial cell differentiation);GO:0060253(negative regulation of glial cell proliferation);GO:0003181(atrioventricular valve morphogenesis);GO:0003682(chromatin binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0005112(Notch binding);GO:0031490(chromatin DNA binding);GO:0043565(sequence-specific DNA binding);GO:0046982(protein heterodimerization activity);GO:0001701(in utero embryonic development);GO:0001708(cell fate specification);GO:0001889(liver development);GO:0002040(sprouting angiogenesis);GO:0002052(positive regulation of neuroblast proliferation);GO:0002437(inflammatory response to antigenic stimulus);GO:0003157(endocardium development);GO:0003160(endocardium morphogenesis);GO:0003162(atrioventricular node development);GO:0003192(mitral valve formation);GO:0003197(endocardial cushion development);GO:0003207(cardiac chamber formation);GO:0003213(cardiac right atrium morphogenesis);GO:0003219(cardiac right ventricle formation);GO:0003241(growth involved in heart morphogenesis);GO:0003256(regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation);GO:0003264(regulation of cardioblast proliferation);GO:0003270(Notch signaling pathway involved in regulation of secondary heart field cardioblast proliferation);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0006959(humoral immune response);GO:0007221(positive regulation of transcription of Notch receptor target);GO:0007283(spermatogenesis);GO:0007386(compartment pattern specification);GO:0007409(axonogenesis);GO:0007420(brain development);GO:0007440(foregut morphogenesis);GO:0007492(endoderm development);GO:0007507(heart development);GO:0008544(epidermis development);GO:0008593(regulation of Notch signaling pathway);GO:0009912(auditory receptor cell fate commitment);GO:0010001(glial cell differentiation);GO:0010468(regulation of gene expression);GO:0014031(mesenchymal cell development);GO:0014807(regulation of somitogenesis);GO:0021515(cell differentiation in spinal cord);GO:0021915(neural tube development);GO:0030182(neuron differentiation);GO:0030216(keratinocyte differentiation);GO:0030324(lung development);GO:0030326(embryonic limb morphogenesis);GO:0030334(regulation of cell migration);GO:0030900(forebrain development);GO:0031069(hair follicle morphogenesis);GO:0031100(animal organ regeneration);GO:0031960(response to corticosteroid);GO:0032495(response to muramyl dipeptide);GO:0032496(response to lipopolysaccharide);GO:0035116(embryonic hindlimb morphogenesis);GO:0035914(skeletal muscle cell differentiation);GO:0042127(regulation of cell proliferation);GO:0042246(tissue regeneration);GO:0043065(positive regulation of apoptotic process);GO:0045070(positive regulation of viral genome replication);GO:0045165(cell fate commitment);GO:0045596(negative regulation of cell differentiation);GO:0045603(positive regulation of endothelial cell differentiation);GO:0045607(regulation of auditory receptor cell differentiation);GO:0045608(negative regulation of auditory receptor cell differentiation);GO:0045618(positive regulation of keratinocyte differentiation);GO:0045665(negative regulation of neuron differentiation);GO:0045687(positive regulation of glial cell differentiation);GO:0045747(positive regulation of Notch signaling pathway);GO:0045955(negative regulation of calcium ion-dependent exocytosis);GO:0046533(negative regulation of photoreceptor cell differentiation);GO:0048103(somatic stem cell division);GO:0048663(neuron fate commitment);GO:0048708(astrocyte differentiation);GO:0048709(oligodendrocyte differentiation);GO:0048715(negative regulation of oligodendrocyte differentiation);GO:0048754(branching morphogenesis of an epithelial tube);GO:0048845(venous blood vessel morphogenesis);GO:0050678(regulation of epithelial cell proliferation);GO:0050679(positive regulation of epithelial cell proliferation);GO:0050767(regulation of neurogenesis);GO:0060038(cardiac muscle cell proliferation);GO:0060528(secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development);GO:0060548(negative regulation of cell death);GO:0060740(prostate gland epithelium morphogenesis);GO:0060768(regulation of epithelial cell proliferation involved in prostate gland development);GO:0060842(arterial endothelial cell differentiation);GO:0060843(venous endothelial cell differentiation);GO:0060979(vasculogenesis involved in coronary vascular morphogenesis);GO:0061419(positive regulation of transcription from RNA polymerase II promoter in response to hypoxia);GO:0070986(left/right axis specification);GO:0071372(cellular response to follicle-stimulating hormone stimulus);GO:0072017(distal tubule development);GO:0072044(collecting duct development);GO:0072144(glomerular mesangial cell development);GO:0072602(interleukin-4 secretion);GO:0090090(negative regulation of canonical Wnt signaling pathway);GO:1902263(apoptotic process involved in embryonic digit morphogenesis);GO:1903849(positive regulation of aorta morphogenesis);GO:2000974(negative regulation of pro-B cell differentiation);GO:0001669(acrosomal vesicle);GO:0002193(MAML1-RBP-Jkappa- ICN1 complex);GO:0005737(cytoplasm);GO:0005783(endoplasmic reticulum);GO:0005794(Golgi apparatus);GO:0009986(cell surface);GO:0031410(cytoplasmic vesicle);GO:0071944(cell periphery);GO:0071944(cell periphery)","04330(Notch signaling pathway);04658(Th1 and Th2 cell differentiation);04919(Thyroid hormone signaling pathway);05200(Pathways in cancer);05206(MicroRNAs in cancer);05224(Breast cancer);05020(Prion diseases);05165(Human papillomavirus infection);01522(Endocrine resistance);01522(Endocrine resistance)","K02599","NA","notch 1 [Source:HGNC Symbol;Acc:HGNC:7881]",{"v":29.6920332769231,"d":"29.69"},{"v":5.19695077945344,"d":"5.20"},{"v":5.71335664642292,"d":"5.71"},{"v":2.51433859047953,"d":"2.51"},{"v":1.02503099270421E-3,"d":"0.00"},{"v":0.0743980307392123,"d":"0.07"},"up","yes"]
["MSTRG.3316","PCED1B","ENST00000546455;ENST00000549630;ENST00000432328;ENST00000549500;ENST00000551777;MSTRG.3316.4;MSTRG.3316.1","GO:0005515(protein binding);GO:0005515(protein binding)","NA","NA","NA","PC-esterase domain containing 1B [Source:HGNC Symbol;Acc:HGNC:28255]",{"v":8.93339668691251,"d":"8.93"},{"v":1.54045584815618,"d":"1.54"},{"v":5.79919034849663,"d":"5.80"},{"v":2.53585149304271,"d":"2.54"},{"v":0.00106175185449512,"d":"0.00"},{"v":0.0765846228959738,"d":"0.08"},"up","yes"]
["MSTRG.1828","ZMIZ1","ENST00000334512;ENST00000446377;MSTRG.1828.2;MSTRG.1828.4;ENST00000478357","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016607(nuclear speck);GO:0043231(intracellular membrane-bounded organelle);GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0005654(nucleoplasm);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0045582(positive regulation of T cell differentiation);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0045747(positive regulation of Notch signaling pathway);GO:0001570(vasculogenesis);GO:0001701(in utero embryonic development);GO:0003007(heart morphogenesis);GO:0007296(vitellogenesis);GO:0007569(cell aging);GO:0048146(positive regulation of fibroblast proliferation);GO:0048589(developmental growth);GO:0048844(artery morphogenesis);GO:0048844(artery morphogenesis)","NA","NA","NA","zinc finger MIZ-type containing 1 [Source:HGNC Symbol;Acc:HGNC:16493]",{"v":8.77652657530775,"d":"8.78"},{"v":1.54406969134685,"d":"1.54"},{"v":5.6840223109698,"d":"5.68"},{"v":2.50691221746991,"d":"2.51"},{"v":0.00107881248140282,"d":"0.00"},{"v":0.0768142789149629,"d":"0.08"},"up","yes"]
["MSTRG.2549","FAM89B;SSSCA1","ENST00000449319;ENST00000530349;ENST00000309328;ENST00000316409;ENST00000526433;ENST00000531405;ENST00000527413;ENST00000527920","GO:0005737(cytoplasm);GO:0009986(cell surface);GO:0030512(negative regulation of transforming growth factor beta receptor signaling pathway);GO:0001222(transcription corepressor binding);GO:0060392(negative regulation of SMAD protein import into nucleus);GO:0051301(cell division);GO:0005515(protein binding);GO:0007049(cell cycle);GO:0000278(mitotic cell cycle);GO:0042802(identical protein binding);GO:0042802(identical protein binding)","NA","NA","NA","family with sequence similarity 89 member B [Source:HGNC Symbol;Acc:HGNC:16708];Sjogren syndrome/scleroderma autoantigen 1 [Source:HGNC Symbol;Acc:HGNC:11328]",{"v":3.15074829433498,"d":"3.15"},{"v":12.4311111949918,"d":"12.43"},{"v":0.253456689825471,"d":"0.25"},{"v":-1.98018885145451,"d":"-1.98"},{"v":0.00108104062905806,"d":"0.00"},{"v":0.0768142789149629,"d":"0.08"},"down","yes"]
["MSTRG.11078","C3orf38","ENST00000318887;ENST00000485219;ENST00000464919","GO:0005634(nucleus);GO:0006915(apoptotic process);GO:0003674(molecular_function);GO:0043065(positive regulation of apoptotic process);GO:0043065(positive regulation of apoptotic process)","NA","NA","NA","chromosome 3 open reading frame 38 [Source:HGNC Symbol;Acc:HGNC:28384]",{"v":1.55342987665325,"d":"1.55"},{"v":6.12012817481311,"d":"6.12"},{"v":0.253823095249257,"d":"0.25"},{"v":-1.97810474956308,"d":"-1.98"},{"v":0.00108477927684956,"d":"0.00"},{"v":0.0768142789149629,"d":"0.08"},"down","yes"]
["MSTRG.8673","MCFD2","ENST00000319466;ENST00000409207;ENST00000409147;ENST00000434262;ENST00000477791;ENST00000409913;ENST00000417180;ENST00000479225;ENST00000409105;ENST00000409800;ENST00000409218;ENST00000444761;ENST00000487121;ENST00000409973;ENST00000470873","GO:0006810(transport);GO:0015031(protein transport);GO:0046872(metal ion binding);GO:0005509(calcium ion binding);GO:0005794(Golgi apparatus);GO:0005783(endoplasmic reticulum);GO:0016192(vesicle-mediated transport);GO:0000139(Golgi membrane);GO:0005789(endoplasmic reticulum membrane);GO:0006888(ER to Golgi vesicle-mediated transport);GO:0048208(COPII vesicle coating);GO:0012507(ER to Golgi transport vesicle membrane);GO:0033116(endoplasmic reticulum-Golgi intermediate compartment membrane);GO:0005793(endoplasmic reticulum-Golgi intermediate compartment);GO:0018279(protein N-linked glycosylation via asparagine);GO:0018279(protein N-linked glycosylation via asparagine)","NA","NA","NA","multiple coagulation factor deficiency 2 [Source:HGNC Symbol;Acc:HGNC:18451]",{"v":0.965865865365365,"d":"0.97"},{"v":3.82224238972306,"d":"3.82"},{"v":0.252696131454747,"d":"0.25"},{"v":-1.98452451676919,"d":"-1.98"},{"v":1.1090017296429E-3,"d":"0.00"},{"v":0.0780535580990485,"d":"0.08"},"down","yes"]
["MSTRG.14647","COMMD5","ENST00000450361;ENST00000533270;ENST00000530332;ENST00000305103;MSTRG.14647.1;ENST00000543949;ENST00000529143;ENST00000402718","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0005515(protein binding);GO:0005515(protein binding)","NA","NA","NA","COMM domain containing 5 [Source:HGNC Symbol;Acc:HGNC:17902]",{"v":3.95060757885792,"d":"3.95"},{"v":0.674329216519375,"d":"0.67"},{"v":5.85857394589755,"d":"5.86"},{"v":2.55054953639569,"d":"2.55"},{"v":0.00113195570533351,"d":"0.00"},{"v":0.0791891663014338,"d":"0.08"},"up","yes"]
["ENSG00000223855","HRAT92","ENST00000452622","NA","NA","NA","NA","heart tissue-associated transcript 92 [Source:NCBI gene;Acc:441307]",{"v":0.363199,"d":"0.36"},{"v":1.474542,"d":"1.47"},{"v":0.246313092472103,"d":"0.25"},{"v":-2.02143478031654,"d":"-2.02"},{"v":0.00115096231469669,"d":"0.00"},{"v":0.0800366788058244,"d":"0.08"},"down","yes"]
["ENSG00000181704","YIPF6","ENST00000462683;ENST00000374643;ENST00000374622;ENST00000451537;ENST00000496576;ENST00000462972;ENST00000470730","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005515(protein binding);GO:0005783(endoplasmic reticulum);GO:0042802(identical protein binding);GO:0060576(intestinal epithelial cell development);GO:0005801(cis-Golgi network);GO:0005802(trans-Golgi network);GO:0030134(ER to Golgi transport vesicle);GO:0030134(ER to Golgi transport vesicle)","NA","NA","NA","Yip1 domain family member 6 [Source:HGNC Symbol;Acc:HGNC:28304]",{"v":0.333254215480226,"d":"0.33"},{"v":1.32965638384181,"d":"1.33"},{"v":0.250631832050733,"d":"0.25"},{"v":-1.99635843591284,"d":"-2.00"},{"v":0.00116377764577353,"d":"0.00"},{"v":0.0804461297640952,"d":"0.08"},"down","yes"]
["ENSG00000168229","PTGDR","ENST00000306051;ENST00000553372","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0004930(G-protein coupled receptor activity);GO:0007186(G-protein coupled receptor signaling pathway);GO:0005886(plasma membrane);GO:0004871(signal transducer activity);GO:0007165(signal transduction);GO:0005515(protein binding);GO:0097755(positive regulation of blood vessel diameter);GO:0004957(prostaglandin E receptor activity);GO:0071380(cellular response to prostaglandin E stimulus);GO:0001785(prostaglandin J receptor activity);GO:0004956(prostaglandin D receptor activity);GO:0006954(inflammatory response);GO:0030238(male sex determination);GO:0030431(sleep);GO:0046085(adenosine metabolic process);GO:0071799(cellular response to prostaglandin D stimulus);GO:0071799(cellular response to prostaglandin D stimulus)","04080(Neuroactive ligand-receptor interaction);04080(Neuroactive ligand-receptor interaction)","K04332","NA","prostaglandin D2 receptor [Source:HGNC Symbol;Acc:HGNC:9591]",{"v":0.388974464886251,"d":"0.39"},{"v":1.58829066073195,"d":"1.59"},{"v":0.244901310889151,"d":"0.24"},{"v":-2.02972759861627,"d":"-2.03"},{"v":0.00119024959774485,"d":"0.00"},{"v":0.0817891631870473,"d":"0.08"},"down","yes"]
["MSTRG.13953","AC018638.4","MSTRG.13953.1;ENST00000465971","NA","NA","NA","NA",null,{"v":7.96769584615385,"d":"7.97"},{"v":1.39055272027972,"d":"1.39"},{"v":5.72987685396861,"d":"5.73"},{"v":2.5185041330349,"d":"2.52"},{"v":0.00120076269073462,"d":"0.00"},{"v":0.0820262183970657,"d":"0.08"},"up","yes"]
["MSTRG.3370","DIP2B","ENST00000301180;ENST00000546719;ENST00000546732;ENST00000549620","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0003824(catalytic activity);GO:0008152(metabolic process);GO:0003674(molecular_function);GO:0008150(biological_process);GO:0070062(extracellular exosome);GO:0070062(extracellular exosome)","NA","NA","NA","disco interacting protein 2 homolog B [Source:HGNC Symbol;Acc:HGNC:29284]",{"v":9.84705142737188,"d":"9.85"},{"v":1.77064607296593,"d":"1.77"},{"v":5.56127595328948,"d":"5.56"},{"v":2.47541592616702,"d":"2.48"},{"v":1.2534737370184E-3,"d":"0.00"},{"v":0.0850746673837941,"d":"0.09"},"up","yes"]
["MSTRG.5289","C15orf39","ENST00000567617;ENST00000394987;ENST00000565074;MSTRG.5289.2;ENST00000564848;ENST00000562637","GO:0005829(cytosol);GO:0005829(cytosol)","NA","NA","NA","chromosome 15 open reading frame 39 [Source:HGNC Symbol;Acc:HGNC:24497]",{"v":37.742886695769,"d":"37.74"},{"v":6.80457438381464,"d":"6.80"},{"v":5.54669323411972,"d":"5.55"},{"v":2.47162793785692,"d":"2.47"},{"v":1.2600398510301E-3,"d":"0.00"},{"v":0.0850746673837941,"d":"0.09"},"up","yes"]
["MSTRG.10152","CRKL","ENST00000354336","GO:0003723(RNA binding);GO:0005515(protein binding);GO:0005829(cytosol);GO:0045296(cadherin binding);GO:0070062(extracellular exosome);GO:0004871(signal transducer activity);GO:0001784(phosphotyrosine residue binding);GO:0005070(SH3/SH2 adaptor activity);GO:0035556(intracellular signal transduction);GO:0007265(Ras protein signal transduction);GO:0000186(activation of MAPKK activity);GO:0005768(endosome);GO:1900026(positive regulation of substrate adhesion-dependent cell spreading);GO:0008284(positive regulation of cell proliferation);GO:0007254(JNK cascade);GO:0001568(blood vessel development);GO:0007389(pattern specification process);GO:0007507(heart development);GO:0009887(animal organ morphogenesis);GO:0009952(anterior/posterior pattern specification);GO:0048538(thymus development);GO:0060017(parathyroid gland development);GO:0005737(cytoplasm)","04015(Rap1 signaling pathway);04010(MAPK signaling pathway);04012(ErbB signaling pathway);04510(Focal adhesion);04810(Regulation of actin cytoskeleton);04666(Fc gamma R-mediated phagocytosis);04062(Chemokine signaling pathway);04910(Insulin signaling pathway);04722(Neurotrophin signaling pathway);05200(Pathways in cancer);05206(MicroRNAs in cancer);05220(Chronic myeloid leukemia);05211(Renal cell carcinoma);05131(Shigellosis);05100(Bacterial invasion of epithelial cells)","K04438","NA","CRK like proto-oncogene, adaptor protein [Source:HGNC Symbol;Acc:HGNC:2363]",{"v":2.281725,"d":"2.28"},{"v":8.730256,"d":"8.73"},{"v":0.261358315265898,"d":"0.26"},{"v":-1.93589903468259,"d":"-1.94"},{"v":1.28350456402572E-3,"d":"0.00"},{"v":0.08576955044323,"d":"0.09"},"down","yes"]
["MSTRG.1475","TOMM20","ENST00000366607;ENST00000467767","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0006886(intracellular protein transport);GO:0015031(protein transport);GO:0006605(protein targeting);GO:0005739(mitochondrion);GO:0051082(unfolded protein binding);GO:0005740(mitochondrial envelope);GO:0005741(mitochondrial outer membrane);GO:0005742(mitochondrial outer membrane translocase complex);GO:0005515(protein binding);GO:0016579(protein deubiquitination);GO:0031012(extracellular matrix);GO:0006626(protein targeting to mitochondrion);GO:0015266(protein channel activity);GO:0030150(protein import into mitochondrial matrix);GO:0016236(macroautophagy);GO:0044233(ER-mitochondrion membrane contact site);GO:0015450(P-P-bond-hydrolysis-driven protein transmembrane transporter activity);GO:0030943(mitochondrion targeting sequence binding);GO:0016031(tRNA import into mitochondrion);GO:0070096(mitochondrial outer membrane translocase complex assembly);GO:0031307(integral component of mitochondrial outer membrane);GO:0031307(integral component of mitochondrial outer membrane)","NA","NA","NA","translocase of outer mitochondrial membrane 20 [Source:HGNC Symbol;Acc:HGNC:20947]",{"v":4.58060118492377,"d":"4.58"},{"v":17.4807278898927,"d":"17.48"},{"v":0.262037211137659,"d":"0.26"},{"v":-1.93215639567499,"d":"-1.93"},{"v":1.28510305494894E-3,"d":"0.00"},{"v":0.08576955044323,"d":"0.09"},"down","yes"]
["MSTRG.13468","TNRC18","MSTRG.13468.3;ENST00000430969;ENST00000455076;ENST00000399537;ENST00000497663;ENST00000434361;ENST00000440081;ENST00000464852;ENST00000328270;ENST00000413081;ENST00000399434","GO:0005634(nucleus);GO:0005829(cytosol);GO:0005739(mitochondrion);GO:0031965(nuclear membrane);GO:0003682(chromatin binding);GO:0000976(transcription regulatory region sequence-specific DNA binding);GO:0000785(chromatin);GO:0006342(chromatin silencing);GO:0031507(heterochromatin assembly);GO:0005677(chromatin silencing complex);GO:0005677(chromatin silencing complex)","NA","NA","NA","trinucleotide repeat containing 18 [Source:HGNC Symbol;Acc:HGNC:11962]",{"v":8.51008313156453,"d":"8.51"},{"v":1.54044610127573,"d":"1.54"},{"v":5.52442771254174,"d":"5.52"},{"v":2.46582502033371,"d":"2.47"},{"v":0.00130596780014386,"d":"0.00"},{"v":0.0866640232175462,"d":"0.09"},"up","yes"]
["MSTRG.15492","HCFC1","ENST00000310441;ENST00000444191;ENST00000369984","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0006355(regulation of transcription, DNA-templated);GO:0016569(covalent chromatin modification);GO:0005515(protein binding);GO:0007049(cell cycle);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0003713(transcription coactivator activity);GO:0042802(identical protein binding);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0005654(nucleoplasm);GO:0045296(cadherin binding);GO:0043254(regulation of protein complex assembly);GO:0050821(protein stabilization);GO:0010628(positive regulation of gene expression);GO:0016579(protein deubiquitination);GO:0003682(chromatin binding);GO:0016032(viral process);GO:0006366(transcription from RNA polymerase II promoter);GO:0071339(MLL1 complex);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0007005(mitochondrion organization);GO:0048188(Set1C/COMPASS complex);GO:0045787(positive regulation of cell cycle);GO:0043995(histone acetyltransferase activity (H4-K5 specific));GO:0043996(histone acetyltransferase activity (H4-K8 specific));GO:0046972(histone acetyltransferase activity (H4-K16 specific));GO:0043981(histone H4-K5 acetylation);GO:0043982(histone H4-K8 acetylation);GO:0043984(histone H4-K16 acetylation);GO:0000123(histone acetyltransferase complex);GO:0005671(Ada2/Gcn5/Ada3 transcription activator complex);GO:0043025(neuronal cell body);GO:0033613(activating transcription factor binding);GO:0070461(SAGA-type complex);GO:0001205(transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding);GO:0019046(release from viral latency);GO:0071407(cellular response to organic cyclic compound);GO:0030424(axon);GO:0030425(dendrite);GO:0030425(dendrite)","05168(Herpes simplex infection);05168(Herpes simplex infection)","K14966","NA","host cell factor C1 [Source:HGNC Symbol;Acc:HGNC:4839]",{"v":8.5507331068414,"d":"8.55"},{"v":1.54751343558418,"d":"1.55"},{"v":5.52546615119599,"d":"5.53"},{"v":2.46609618136378,"d":"2.47"},{"v":1.31849700148942E-3,"d":"0.00"},{"v":0.0867119169161034,"d":"0.09"},"up","yes"]
["ENSG00000116539","ASH1L","ENST00000392403;ENST00000368346;ENST00000492987;ENST00000548830;ENST00000477427;ENST00000478837;ENST00000548566","GO:0005634(nucleus);GO:0005794(Golgi apparatus);GO:0046872(metal ion binding);GO:0005654(nucleoplasm);GO:0008168(methyltransferase activity);GO:0016740(transferase activity);GO:0032259(methylation);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0016569(covalent chromatin modification);GO:0003677(DNA binding);GO:0005694(chromosome);GO:0030054(cell junction);GO:0003682(chromatin binding);GO:0018024(histone-lysine N-methyltransferase activity);GO:0005923(bicellular tight junction);GO:0070062(extracellular exosome);GO:0007267(cell-cell signaling);GO:0006366(transcription from RNA polymerase II promoter);GO:0006323(DNA packaging);GO:0046975(histone methyltransferase activity (H3-K36 specific));GO:0097676(histone H3-K36 dimethylation);GO:0042800(histone methyltransferase activity (H3-K4 specific));GO:0001501(skeletal system development);GO:0002674(negative regulation of acute inflammatory response);GO:0007338(single fertilization);GO:0009791(post-embryonic development);GO:0010468(regulation of gene expression);GO:0032635(interleukin-6 production);GO:0043124(negative regulation of I-kappaB kinase/NF-kappaB signaling);GO:0043409(negative regulation of MAPK cascade);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0046697(decidualization);GO:0048733(sebaceous gland development);GO:0050728(negative regulation of inflammatory response);GO:0051568(histone H3-K4 methylation);GO:0061038(uterus morphogenesis);GO:0097722(sperm motility);GO:1903699(tarsal gland development);GO:1903709(uterine gland development);GO:1903709(uterine gland development)","00310(Lysine degradation);00310(Lysine degradation)","K06101","EC:2.1.1.43","ASH1 like histone lysine methyltransferase [Source:HGNC Symbol;Acc:HGNC:19088]",{"v":5.72922253181408,"d":"5.73"},{"v":1.03561828286703,"d":"1.04"},{"v":5.53217592485251,"d":"5.53"},{"v":2.4678470353526,"d":"2.47"},{"v":1.32162312013694E-3,"d":"0.00"},{"v":0.0867119169161034,"d":"0.09"},"up","yes"]
["MSTRG.4554","TMED10","ENST00000303575;ENST00000556969;ENST00000555036;ENST00000555873;ENST00000622441;ENST00000555085;ENST00000557670","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0015031(protein transport);GO:0005794(Golgi apparatus);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0042470(melanosome);GO:0031410(cytoplasmic vesicle);GO:0032403(protein complex binding);GO:0001822(kidney development);GO:0007030(Golgi organization);GO:0043279(response to alkaloid);GO:0045055(regulated exocytosis);GO:0048199(vesicle targeting, to, from or within Golgi);GO:0051259(protein oligomerization);GO:0005793(endoplasmic reticulum-Golgi intermediate compartment);GO:0005801(cis-Golgi network);GO:0030137(COPI-coated vesicle);GO:0030667(secretory granule membrane);GO:0042589(zymogen granule membrane);GO:0043231(intracellular membrane-bounded organelle);GO:0070765(gamma-secretase complex);GO:0006886(intracellular protein transport);GO:0016192(vesicle-mediated transport);GO:0070062(extracellular exosome);GO:0006890(retrograde vesicle-mediated transport, Golgi to ER);GO:0006888(ER to Golgi vesicle-mediated transport);GO:0019905(syntaxin binding);GO:0030140(trans-Golgi network transport vesicle);GO:0000139(Golgi membrane);GO:0030133(transport vesicle);GO:0048208(COPII vesicle coating);GO:0012507(ER to Golgi transport vesicle membrane);GO:0033116(endoplasmic reticulum-Golgi intermediate compartment membrane);GO:0035459(cargo loading into vesicle);GO:0030658(transport vesicle membrane);GO:0035964(COPI-coated vesicle budding);GO:0048205(COPI coating of Golgi vesicle);GO:1902003(regulation of amyloid-beta formation);GO:1902003(regulation of amyloid-beta formation)","NA","NA","NA","transmembrane p24 trafficking protein 10 [Source:HGNC Symbol;Acc:HGNC:16998]",{"v":5.49082145195014,"d":"5.49"},{"v":20.807089106353,"d":"20.81"},{"v":0.26389186031186,"d":"0.26"},{"v":-1.92198124315769,"d":"-1.92"},{"v":0.0013407786551811,"d":"0.00"},{"v":0.087474508554034,"d":"0.09"},"down","yes"]
["ENSG00000169203","NPIPB12","ENST00000458643;ENST00000550690;ENST00000550665;ENST00000551448;ENST00000548346;ENST00000617311;ENST00000552123;ENST00000549733;ENST00000547235","GO:0005654(nucleoplasm);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016021(integral component of membrane)","NA","NA","NA","nuclear pore complex interacting protein family, member B12 [Source:HGNC Symbol;Acc:HGNC:37491]",{"v":2.45004601269915,"d":"2.45"},{"v":0.429421156545832,"d":"0.43"},{"v":5.70546181843199,"d":"5.71"},{"v":2.51234366761758,"d":"2.51"},{"v":0.00135964915653057,"d":"0.00"},{"v":0.0882100874569249,"d":"0.09"},"up","yes"]
["ENSG00000133393","FOPNL","ENST00000255759;ENST00000575938;ENST00000575073;ENST00000572415;ENST00000573087;ENST00000575744;ENST00000573396;ENST00000573968","GO:0005737(cytoplasm);GO:0005634(nucleus);GO:0031514(motile cilium);GO:0005813(centrosome);GO:0005856(cytoskeleton);GO:0042995(cell projection);GO:0005815(microtubule organizing center);GO:0034453(microtubule anchoring);GO:0060271(cilium assembly);GO:0005929(cilium);GO:0030030(cell projection organization);GO:0005814(centriole);GO:0036064(ciliary basal body);GO:0034451(centriolar satellite);GO:0034451(centriolar satellite)","NA","NA","NA","FGFR1OP N-terminal like [Source:HGNC Symbol;Acc:HGNC:26435]",{"v":6.56050349435383,"d":"6.56"},{"v":1.16415024048515,"d":"1.16"},{"v":5.63544400559484,"d":"5.64"},{"v":2.49452928199195,"d":"2.49"},{"v":1.37667597857673E-3,"d":"0.00"},{"v":0.0888185452178423,"d":"0.09"},"up","yes"]
["MSTRG.14615","PLEC","ENST00000436759;ENST00000345136;ENST00000357649;ENST00000527096;ENST00000398774;ENST00000532346;ENST00000354589;ENST00000322810;ENST00000354958;ENST00000528025;ENST00000527303","GO:0003723(RNA binding);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0003779(actin binding);GO:0005925(focal adhesion);GO:0045111(intermediate filament cytoskeleton);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0008092(cytoskeletal protein binding);GO:0030054(cell junction);GO:0045296(cadherin binding);GO:0070062(extracellular exosome);GO:0042383(sarcolemma);GO:0031012(extracellular matrix);GO:0005886(plasma membrane);GO:0008307(structural constituent of muscle);GO:0030506(ankyrin binding);GO:0031581(hemidesmosome assembly);GO:0030056(hemidesmosome);GO:0043034(costamere);GO:0016528(sarcoplasm);GO:0005903(brush border);GO:0043292(contractile fiber);GO:0043292(contractile fiber)","NA","NA","NA","plectin [Source:HGNC Symbol;Acc:HGNC:9069]",{"v":15.0510942986287,"d":"15.05"},{"v":2.75391709652169,"d":"2.75"},{"v":5.46534037558315,"d":"5.47"},{"v":2.4503113482072,"d":"2.45"},{"v":0.00139784729887936,"d":"0.00"},{"v":0.0896861916126297,"d":"0.09"},"up","yes"]
["MSTRG.12388","CD14","ENST00000302014;MSTRG.12388.1;ENST00000401743;ENST00000498971;ENST00000512545","GO:0016020(membrane);GO:0005794(Golgi apparatus);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0005615(extracellular space);GO:0031225(anchored component of membrane);GO:0045121(membrane raft);GO:0002376(immune system process);GO:0045087(innate immune response);GO:0006954(inflammatory response);GO:0070062(extracellular exosome);GO:0071222(cellular response to lipopolysaccharide);GO:0010008(endosome membrane);GO:0043312(neutrophil degranulation);GO:0006915(apoptotic process);GO:0002224(toll-like receptor signaling pathway);GO:0002755(MyD88-dependent toll-like receptor signaling pathway);GO:0002756(MyD88-independent toll-like receptor signaling pathway);GO:0007249(I-kappaB kinase/NF-kappaB signaling);GO:0034128(negative regulation of MyD88-independent toll-like receptor signaling pathway);GO:0034142(toll-like receptor 4 signaling pathway);GO:0035666(TRIF-dependent toll-like receptor signaling pathway);GO:0070266(necroptotic process);GO:0097190(apoptotic signaling pathway);GO:0046696(lipopolysaccharide receptor complex);GO:0007166(cell surface receptor signaling pathway);GO:0030667(secretory granule membrane);GO:0038123(toll-like receptor TLR1:TLR2 signaling pathway);GO:0038124(toll-like receptor TLR6:TLR2 signaling pathway);GO:0071223(cellular response to lipoteichoic acid);GO:0071726(cellular response to diacyl bacterial lipopeptide);GO:0071727(cellular response to triacyl bacterial lipopeptide);GO:0032760(positive regulation of tumor necrosis factor production);GO:0032729(positive regulation of interferon-gamma production);GO:0031362(anchored component of external side of plasma membrane);GO:0001530(lipopolysaccharide binding);GO:0001847(opsonin receptor activity);GO:0016019(peptidoglycan receptor activity);GO:0070891(lipoteichoic acid binding);GO:0071723(lipopeptide binding);GO:0002237(response to molecule of bacterial origin);GO:0006898(receptor-mediated endocytosis);GO:0006909(phagocytosis);GO:0009408(response to heat);GO:0009617(response to bacterium);GO:0031663(lipopolysaccharide-mediated signaling pathway);GO:0032026(response to magnesium ion);GO:0032481(positive regulation of type I interferon production);GO:0032496(response to lipopolysaccharide);GO:0034612(response to tumor necrosis factor);GO:0045471(response to ethanol);GO:0045807(positive regulation of endocytosis);GO:0050715(positive regulation of cytokine secretion);GO:0051602(response to electrical stimulus);GO:0071219(cellular response to molecule of bacterial origin);GO:1901224(positive regulation of NIK/NF-kappaB signaling);GO:2000484(positive regulation of interleukin-8 secretion);GO:0009897(external side of plasma membrane);GO:0009986(cell surface);GO:0009986(cell surface)","04010(MAPK signaling pathway);04064(NF-kappa B signaling pathway);04145(Phagosome);04810(Regulation of actin cytoskeleton);04640(Hematopoietic cell lineage);04620(Toll-like receptor signaling pathway);05202(Transcriptional misregulation in cancers);05221(Acute myeloid leukemia);05130(Pathogenic Escherichia coli infection);05132(Salmonella infection);05133(Pertussis);05134(Legionellosis);05152(Tuberculosis);05146(Amoebiasis);05146(Amoebiasis)","K04391","NA","CD14 molecule [Source:HGNC Symbol;Acc:HGNC:1628]",{"v":12.3920991169065,"d":"12.39"},{"v":46.566669743705,"d":"46.57"},{"v":0.266115210409301,"d":"0.27"},{"v":-1.90987712171277,"d":"-1.91"},{"v":1.41449296188085E-3,"d":"0.00"},{"v":0.0902555316830893,"d":"0.09"},"down","yes"]
["MSTRG.10686","NR2C2","ENST00000617312;ENST00000323373;ENST00000406272;ENST00000475707;ENST00000393102;ENST00000478572;ENST00000439011;ENST00000437120;ENST00000413194;ENST00000425241;ENST00000435454;ENST00000413118;ENST00000495282","GO:0005634(nucleus);GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0005654(nucleoplasm);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0043565(sequence-specific DNA binding);GO:0003707(steroid hormone receptor activity);GO:0043401(steroid hormone mediated signaling pathway);GO:0030154(cell differentiation);GO:0007283(spermatogenesis);GO:0005515(protein binding);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0001228(transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding);GO:0007399(nervous system development);GO:0003713(transcription coactivator activity);GO:0004872(receptor activity);GO:0046982(protein heterodimerization activity);GO:0006367(transcription initiation from RNA polymerase II promoter);GO:0001077(transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0000977(RNA polymerase II regulatory region sequence-specific DNA binding);GO:0000977(RNA polymerase II regulatory region sequence-specific DNA binding)","NA","NA","NA","nuclear receptor subfamily 2 group C member 2 [Source:HGNC Symbol;Acc:HGNC:7972]",{"v":3.89431248388461,"d":"3.89"},{"v":0.708955881989679,"d":"0.71"},{"v":5.49302514136035,"d":"5.49"},{"v":2.45760089503006,"d":"2.46"},{"v":1.43111224596871E-3,"d":"0.00"},{"v":0.0908169754777851,"d":"0.09"},"up","yes"]
["MSTRG.3478","LRP1","ENST00000243077;ENST00000556830;ENST00000556356;ENST00000556247;ENST00000554174;ENST00000338962;ENST00000553446;ENST00000553277;ENST00000555941","GO:0005730(nucleolus);GO:0005829(cytosol);GO:0005509(calcium ion binding);GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0046872(metal ion binding);GO:0005765(lysosomal membrane);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0007275(multicellular organism development);GO:0005905(clathrin-coated pit);GO:0005925(focal adhesion);GO:0006898(receptor-mediated endocytosis);GO:0005887(integral component of plasma membrane);GO:0006897(endocytosis);GO:0042953(lipoprotein transport);GO:0004872(receptor activity);GO:1904646(cellular response to amyloid-beta);GO:0030666(endocytic vesicle membrane);GO:0001523(retinoid metabolic process);GO:0043235(receptor complex);GO:0030178(negative regulation of Wnt signaling pathway);GO:0010942(positive regulation of cell death);GO:0014912(negative regulation of smooth muscle cell migration);GO:0034185(apolipoprotein binding);GO:0010875(positive regulation of cholesterol efflux);GO:0097242(amyloid-beta clearance);GO:0005041(low-density lipoprotein receptor activity);GO:0045807(positive regulation of endocytosis);GO:0051246(regulation of protein metabolic process);GO:1900223(positive regulation of amyloid-beta clearance);GO:1905167(positive regulation of lysosomal protein catabolic process);GO:0032374(regulation of cholesterol transport);GO:0032956(regulation of actin cytoskeleton organization);GO:0002265(astrocyte activation involved in immune response);GO:0035909(aorta morphogenesis);GO:0045732(positive regulation of protein catabolic process);GO:0005044(scavenger receptor activity);GO:0045056(transcytosis);GO:1903078(positive regulation of protein localization to plasma membrane);GO:0032403(protein complex binding);GO:0070325(lipoprotein particle receptor binding);GO:0006629(lipid metabolic process);GO:0098797(plasma membrane protein complex);GO:0002020(protease binding);GO:0016964(alpha-2 macroglobulin receptor activity);GO:0030226(apolipoprotein receptor activity);GO:0032050(clathrin heavy chain binding);GO:0042954(lipoprotein transporter activity);GO:0043395(heparan sulfate proteoglycan binding);GO:0006909(phagocytosis);GO:0007205(protein kinase C-activating G-protein coupled receptor signaling pathway);GO:0007568(aging);GO:0008283(cell proliferation);GO:0010715(regulation of extracellular matrix disassembly);GO:0010977(negative regulation of neuron projection development);GO:0021987(cerebral cortex development);GO:0031623(receptor internalization);GO:0032092(positive regulation of protein binding);GO:0032370(positive regulation of lipid transport);GO:0032429(regulation of phospholipase A2 activity);GO:0042157(lipoprotein metabolic process);GO:0043277(apoptotic cell clearance);GO:0043524(negative regulation of neuron apoptotic process);GO:0051222(positive regulation of protein transport);GO:2000587(negative regulation of platelet-derived growth factor receptor-beta signaling pathway);GO:0005768(endosome);GO:0005769(early endosome);GO:0016323(basolateral plasma membrane);GO:0030136(clathrin-coated vesicle);GO:0030425(dendrite);GO:0043025(neuronal cell body);GO:0043025(neuronal cell body)","04979(Cholesterol metabolism);05010(Alzheimer's disease);05144(Malaria);05144(Malaria)","K04550","NA","LDL receptor related protein 1 [Source:HGNC Symbol;Acc:HGNC:6692]",{"v":7.4064537603052,"d":"7.41"},{"v":1.3620097875138,"d":"1.36"},{"v":5.43788585677117,"d":"5.44"},{"v":2.44304586897973,"d":"2.44"},{"v":0.0014593392789652,"d":"0.00"},{"v":0.0921049296012112,"d":"0.09"},"up","yes"]
["MSTRG.15393","TCEAL8","ENST00000372685;ENST00000360000","GO:0005634(nucleus);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0050699(WW domain binding);GO:0050699(WW domain binding)","NA","NA","NA","transcription elongation factor A like 8 [Source:HGNC Symbol;Acc:HGNC:28683]",{"v":1.28749308510638,"d":"1.29"},{"v":4.97683306382979,"d":"4.98"},{"v":0.258697261610705,"d":"0.26"},{"v":-1.95066331215024,"d":"-1.95"},{"v":1.48235427523854E-3,"d":"0.00"},{"v":0.0930517848559197,"d":"0.09"},"down","yes"]
["ENSG00000196268","ZNF493","ENST00000599461;ENST00000392288;ENST00000355504;ENST00000596302;ENST00000594390;ENST00000339914;ENST00000599517;ENST00000598152","GO:0003676(nucleic acid binding);GO:0006355(regulation of transcription, DNA-templated);GO:0005622(intracellular);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding)","NA","NA","NA","zinc finger protein 493 [Source:HGNC Symbol;Acc:HGNC:23708]",{"v":0.822756603263777,"d":"0.82"},{"v":0.146821920634921,"d":"0.15"},{"v":5.60377224126904,"d":"5.60"},{"v":2.48639832031743,"d":"2.49"},{"v":1.53039472111979E-3,"d":"0.00"},{"v":0.0955509349266886,"d":"0.10"},"up","yes"]
["MSTRG.1372","LPGAT1","ENST00000366996;ENST00000366997;ENST00000498690;MSTRG.1372.3;MSTRG.1372.2;ENST00000488600","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016740(transferase activity);GO:0016746(transferase activity, transferring acyl groups);GO:0006629(lipid metabolic process);GO:0008152(metabolic process);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0008654(phospholipid biosynthetic process);GO:0003674(molecular_function);GO:0008150(biological_process);GO:0003841(1-acylglycerol-3-phosphate O-acyltransferase activity);GO:0036148(phosphatidylglycerol acyl-chain remodeling);GO:0045723(positive regulation of fatty acid biosynthetic process);GO:0047144(2-acylglycerol-3-phosphate O-acyltransferase activity);GO:0047144(2-acylglycerol-3-phosphate O-acyltransferase activity)","00564(Glycerophospholipid metabolism);00564(Glycerophospholipid metabolism)","K13514","EC:2.3.1.-","lysophosphatidylglycerol acyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:28985]",{"v":10.4487454402773,"d":"10.45"},{"v":1.93546909319241,"d":"1.94"},{"v":5.3985596964728,"d":"5.40"},{"v":2.43257455617989,"d":"2.43"},{"v":1.54093532604662E-3,"d":"0.00"},{"v":0.0956945558362537,"d":"0.10"},"up","yes"]
["MSTRG.14468","TP53INP1","ENST00000342697;ENST00000448464","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0010506(regulation of autophagy);GO:0006915(apoptotic process);GO:0006914(autophagy);GO:0031410(cytoplasmic vesicle);GO:0098869(cellular oxidant detoxification);GO:0008285(negative regulation of cell proliferation);GO:0045893(positive regulation of transcription, DNA-templated);GO:0005515(protein binding);GO:0005654(nucleoplasm);GO:0010508(positive regulation of autophagy);GO:0000045(autophagosome assembly);GO:0007050(cell cycle arrest);GO:0005776(autophagosome);GO:0042981(regulation of apoptotic process);GO:1901796(regulation of signal transduction by p53 class mediator);GO:0016605(PML body);GO:0030336(negative regulation of cell migration);GO:0006950(response to stress);GO:0016209(antioxidant activity);GO:0048102(autophagic cell death);GO:0009408(response to heat);GO:0010628(positive regulation of gene expression);GO:0010629(negative regulation of gene expression);GO:0034644(cellular response to UV);GO:0043065(positive regulation of apoptotic process);GO:0048147(negative regulation of fibroblast proliferation);GO:0071361(cellular response to ethanol);GO:0071447(cellular response to hydroperoxide);GO:0072703(cellular response to methyl methanesulfonate);GO:1904761(negative regulation of myofibroblast differentiation);GO:2001235(positive regulation of apoptotic signaling pathway);GO:2001235(positive regulation of apoptotic signaling pathway)","05166(HTLV-I infection);05166(HTLV-I infection)","K15310","NA","tumor protein p53 inducible nuclear protein 1 [Source:HGNC Symbol;Acc:HGNC:18022]",{"v":2.47703942300916,"d":"2.48"},{"v":9.19572793569415,"d":"9.20"},{"v":0.269368498103808,"d":"0.27"},{"v":-1.89234695339226,"d":"-1.89"},{"v":1.55515731162664E-3,"d":"0.00"},{"v":0.0960640524463837,"d":"0.10"},"down","yes"]
["ENSG00000172840","PDP2","ENST00000311765;ENST00000566543;ENST00000561704;ENST00000566805;ENST00000568398;ENST00000568720","GO:0003824(catalytic activity);GO:0006470(protein dephosphorylation);GO:0004722(protein serine/threonine phosphatase activity);GO:0043169(cation binding);GO:0046872(metal ion binding);GO:0016787(hydrolase activity);GO:0005739(mitochondrion);GO:0004721(phosphoprotein phosphatase activity);GO:0005759(mitochondrial matrix);GO:0010510(regulation of acetyl-CoA biosynthetic process from pyruvate);GO:0004741([pyruvate dehydrogenase (lipoamide)] phosphatase activity);GO:0004741([pyruvate dehydrogenase (lipoamide)] phosphatase activity)","NA","NA","NA","pyruvate dehyrogenase phosphatase catalytic subunit 2 [Source:HGNC Symbol;Acc:HGNC:30263]",{"v":0.690859228120516,"d":"0.69"},{"v":0.122136043041607,"d":"0.12"},{"v":5.65647298631713,"d":"5.66"},{"v":2.49990276132194,"d":"2.50"},{"v":1.57500577799594E-3,"d":"0.00"},{"v":0.0967753550257508,"d":"0.10"},"up","yes"]
["ENSG00000187605","TET3","ENST00000409262;ENST00000475405;ENST00000305799","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0016569(covalent chromatin modification);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0007275(multicellular organism development);GO:0051213(dioxygenase activity);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0006493(protein O-linked glycosylation);GO:0080182(histone H3-K4 trimethylation);GO:0070579(methylcytosine dioxygenase activity);GO:0044727(DNA demethylation of male pronucleus);GO:0080111(DNA demethylation);GO:0001940(male pronucleus);GO:0001940(male pronucleus)","NA","NA","NA","tet methylcytosine dioxygenase 3 [Source:HGNC Symbol;Acc:HGNC:28313]",{"v":6.74630094303643,"d":"6.75"},{"v":1.25714016852742,"d":"1.26"},{"v":5.36638722708134,"d":"5.37"},{"v":2.42395116015824,"d":"2.42"},{"v":1.59370406232148E-3,"d":"0.00"},{"v":0.0974088698723122,"d":"0.10"},"up","yes"]
["MSTRG.3600","BTG1;LINC01619","ENST00000256015;MSTRG.3600.6;ENST00000551563;ENST00000552315;ENST00000553207;ENST00000551843;ENST00000552277;ENST00000551306;ENST00000548552","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0006355(regulation of transcription, DNA-templated);GO:0005515(protein binding);GO:0008285(negative regulation of cell proliferation);GO:0019899(enzyme binding);GO:0030308(negative regulation of cell growth);GO:0016477(cell migration);GO:0003712(transcription cofactor activity);GO:0045766(positive regulation of angiogenesis);GO:0019900(kinase binding);GO:2000271(positive regulation of fibroblast apoptotic process);GO:0045663(positive regulation of myoblast differentiation);GO:0006479(protein methylation);GO:0045603(positive regulation of endothelial cell differentiation);GO:0045603(positive regulation of endothelial cell differentiation)","03018(RNA degradation);03018(RNA degradation)","K14443","NA","BTG anti-proliferation factor 1 [Source:HGNC Symbol;Acc:HGNC:1130];long intergenic non-protein coding RNA 1619 [Source:HGNC Symbol;Acc:HGNC:27409]",{"v":6.1376690324979,"d":"6.14"},{"v":22.5970851111644,"d":"22.60"},{"v":0.271613307747622,"d":"0.27"},{"v":-1.88037392844477,"d":"-1.88"},{"v":1.61703197723025E-3,"d":"0.00"},{"v":0.0983172374428007,"d":"0.10"},"down","yes"]
["MSTRG.3311","SLC38A1","ENST00000398637;ENST00000546893;ENST00000550173;ENST00000439706;ENST00000612161;ENST00000549633;ENST00000546519;ENST00000548979;ENST00000551506;MSTRG.3311.5;ENST00000552197","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0015293(symporter activity);GO:0006811(ion transport);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0006814(sodium ion transport);GO:0005887(integral component of plasma membrane);GO:0070062(extracellular exosome);GO:1902475(L-alpha-amino acid transmembrane transport);GO:0015171(amino acid transmembrane transporter activity);GO:0003333(amino acid transmembrane transport);GO:0006865(amino acid transport);GO:0015175(neutral amino acid transmembrane transporter activity);GO:0015804(neutral amino acid transport);GO:0015807(L-amino acid transport);GO:0001504(neurotransmitter uptake);GO:0005283(sodium:amino acid symporter activity);GO:0015179(L-amino acid transmembrane transporter activity);GO:0015186(L-glutamine transmembrane transporter activity);GO:0006868(glutamine transport);GO:0007565(female pregnancy);GO:0030424(axon);GO:0030424(axon)","04724(Glutamatergic synapse);04727(GABAergic synapse);04727(GABAergic synapse)","K14990","NA","solute carrier family 38 member 1 [Source:HGNC Symbol;Acc:HGNC:13447]",{"v":10.1548377448104,"d":"10.15"},{"v":1.89881599011976,"d":"1.90"},{"v":5.34798411096692,"d":"5.35"},{"v":2.41899517914419,"d":"2.42"},{"v":1.63281407634123E-3,"d":"0.00"},{"v":0.0987597388987013,"d":"0.10"},"up","yes"]
["ENSG00000181191","PJA1","ENST00000374571;ENST00000374584;ENST00000477231;ENST00000361478;ENST00000374583","GO:0016567(protein ubiquitination);GO:0061630(ubiquitin protein ligase activity);GO:0046872(metal ion binding);GO:0016740(transferase activity);GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0030163(protein catabolic process);GO:0030163(protein catabolic process)","NA","NA","NA","praja ring finger ubiquitin ligase 1 [Source:HGNC Symbol;Acc:HGNC:16648]",{"v":0.773802637471928,"d":"0.77"},{"v":2.91521361052294,"d":"2.92"},{"v":0.265435999159293,"d":"0.27"},{"v":-1.91356404864576,"d":"-1.91"},{"v":0.00167488192455338,"d":"0.00"},{"v":0.100779294247867,"d":"0.10"},"down","yes"]
["MSTRG.815","HIPK1","ENST00000369558;ENST00000369561;ENST00000369559;ENST00000361587;ENST00000340480;ENST00000503968;ENST00000514621;ENST00000369553","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0005813(centrosome);GO:0005515(protein binding);GO:0001654(eye development);GO:0097191(extrinsic apoptotic signaling pathway);GO:1901796(regulation of signal transduction by p53 class mediator);GO:0045766(positive regulation of angiogenesis);GO:0060216(definitive hemopoiesis);GO:0072577(endothelial cell apoptotic process);GO:0010803(regulation of tumor necrosis factor-mediated signaling pathway);GO:0007224(smoothened signaling pathway);GO:0008284(positive regulation of cell proliferation);GO:0009952(anterior/posterior pattern specification);GO:0010842(retina layer formation);GO:0030182(neuron differentiation);GO:0034333(adherens junction assembly);GO:0042771(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator);GO:0048596(embryonic camera-type eye morphogenesis);GO:0060059(embryonic retina morphogenesis in camera-type eye);GO:0060235(lens induction in camera-type eye);GO:0061072(iris morphogenesis);GO:0016605(PML body);GO:0016607(nuclear speck);GO:0003677(DNA binding);GO:0003677(DNA binding)","04218(Cellular senescence);04218(Cellular senescence)","K08826","EC:2.7.11.1","homeodomain interacting protein kinase 1 [Source:HGNC Symbol;Acc:HGNC:19006]",{"v":20.2145599231681,"d":"20.21"},{"v":3.81275420323276,"d":"3.81"},{"v":5.30182614605174,"d":"5.30"},{"v":2.40648936308686,"d":"2.41"},{"v":0.00171861372011347,"d":"0.00"},{"v":0.102877634699369,"d":"0.10"},"up","yes"]
["MSTRG.14124","GIMAP7","ENST00000313543","GO:0005737(cytoplasm);GO:0043231(intracellular membrane-bounded organelle);GO:0005525(GTP binding);GO:0000166(nucleotide binding);GO:0005829(cytosol);GO:0005794(Golgi apparatus);GO:0005783(endoplasmic reticulum);GO:0042803(protein homodimerization activity);GO:0003924(GTPase activity);GO:0005515(protein binding);GO:0046039(GTP metabolic process);GO:0005811(lipid particle)","NA","NA","NA","GTPase, IMAP family member 7 [Source:HGNC Symbol;Acc:HGNC:22404]",{"v":6.10006,"d":"6.10"},{"v":1.106907,"d":"1.11"},{"v":5.51090561357006,"d":"5.51"},{"v":2.46228941804313,"d":"2.46"},{"v":0.0017341891984955,"d":"0.00"},{"v":0.103277636728863,"d":"0.10"},"up","yes"]
["ENSG00000151914","DST","ENST00000449297;ENST00000524186;ENST00000492944;ENST00000466429;ENST00000524216;ENST00000459869;ENST00000521104;ENST00000523817;ENST00000523943;ENST00000520144;ENST00000361203;ENST00000518464;ENST00000370765;ENST00000523967;ENST00000421834","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0046872(metal ion binding);GO:0005829(cytosol);GO:0005509(calcium ion binding);GO:0007155(cell adhesion);GO:0003779(actin binding);GO:1904115(axon cytoplasm);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005886(plasma membrane);GO:0015630(microtubule cytoskeleton);GO:0005856(cytoskeleton);GO:0042995(cell projection);GO:0005515(protein binding);GO:0008092(cytoskeletal protein binding);GO:0005882(intermediate filament);GO:0008017(microtubule binding);GO:0030054(cell junction);GO:0005874(microtubule);GO:0007229(integrin-mediated signaling pathway);GO:0005925(focal adhesion);GO:0007010(cytoskeleton organization);GO:0030424(axon);GO:0031252(cell leading edge);GO:0070062(extracellular exosome);GO:0005938(cell cortex);GO:0008022(protein C-terminus binding);GO:0009925(basal plasma membrane);GO:0005178(integrin binding);GO:0030018(Z disc);GO:0005635(nuclear envelope);GO:0031410(cytoplasmic vesicle);GO:0045104(intermediate filament cytoskeleton organization);GO:0009611(response to wounding);GO:0048870(cell motility);GO:0051010(microtubule plus-end binding);GO:0005604(basement membrane);GO:0008090(retrograde axonal transport);GO:0030056(hemidesmosome);GO:0035371(microtubule plus-end);GO:0030011(maintenance of cell polarity);GO:0031673(H zone);GO:0016055(Wnt signaling pathway);GO:0016887(ATPase activity);GO:0016887(ATPase activity)","NA","NA","NA","dystonin [Source:HGNC Symbol;Acc:HGNC:1090]",{"v":0.115276559764767,"d":"0.12"},{"v":0.0202110593750738,"d":"0.02"},{"v":5.70363767803963,"d":"5.70"},{"v":2.51188233790068,"d":"2.51"},{"v":0.00176922414222916,"d":"0.00"},{"v":0.104826530427077,"d":"0.10"},"up","yes"]
["MSTRG.997","SLC39A1","ENST00000356205;ENST00000368623;ENST00000537590;ENST00000429040;ENST00000461071;ENST00000368621;ENST00000417348;ENST00000621013;ENST00000310483","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0055085(transmembrane transport);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0006811(ion transport);GO:0005886(plasma membrane);GO:0046873(metal ion transmembrane transporter activity);GO:0030001(metal ion transport);GO:0005385(zinc ion transmembrane transporter activity);GO:0006829(zinc II ion transport);GO:0071577(zinc II ion transmembrane transport);GO:0022890(inorganic cation transmembrane transporter activity);GO:0006812(cation transport);GO:0005102(receptor binding);GO:0001701(in utero embryonic development);GO:0048701(embryonic cranial skeleton morphogenesis);GO:0060173(limb development);GO:0060173(limb development)","NA","NA","NA","solute carrier family 39 member 1 [Source:HGNC Symbol;Acc:HGNC:12876]",{"v":10.4991745076741,"d":"10.50"},{"v":1.96736326269185,"d":"1.97"},{"v":5.33667305208728,"d":"5.34"},{"v":2.41594062823071,"d":"2.42"},{"v":0.00178649412345296,"d":"0.00"},{"v":0.105312468302839,"d":"0.11"},"up","yes"]
["ENSG00000120949","TNFRSF8","ENST00000413146;ENST00000263932;ENST00000417814","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0007165(signal transduction);GO:0005886(plasma membrane);GO:0004888(transmembrane signaling receptor activity);GO:0006955(immune response);GO:0005634(nucleus);GO:0005887(integral component of plasma membrane);GO:0006954(inflammatory response);GO:0070062(extracellular exosome);GO:0097190(apoptotic signaling pathway);GO:0033209(tumor necrosis factor-mediated signaling pathway);GO:0043065(positive regulation of apoptotic process);GO:0007411(axon guidance);GO:0043005(neuron projection);GO:0042535(positive regulation of tumor necrosis factor biosynthetic process);GO:0071260(cellular response to mechanical stimulus);GO:0005031(tumor necrosis factor-activated receptor activity);GO:0032496(response to lipopolysaccharide);GO:0008285(negative regulation of cell proliferation);GO:0048406(nerve growth factor binding);GO:0010977(negative regulation of neuron projection development);GO:0045556(positive regulation of TRAIL biosynthetic process);GO:0045556(positive regulation of TRAIL biosynthetic process)","04060(Cytokine-cytokine receptor interaction);04060(Cytokine-cytokine receptor interaction)","K05145","NA","TNF receptor superfamily member 8 [Source:HGNC Symbol;Acc:HGNC:11923]",{"v":0.363556616372392,"d":"0.36"},{"v":1.38840639807384,"d":"1.39"},{"v":0.261851729347229,"d":"0.26"},{"v":-1.93317796207859,"d":"-1.93"},{"v":0.00180102265575853,"d":"0.00"},{"v":0.105632707582444,"d":"0.11"},"down","yes"]
["MSTRG.5846","ZNF688","ENST00000223459;ENST00000563665;ENST00000567855;ENST00000566632","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0005622(intracellular);GO:0003674(molecular_function);GO:0008150(biological_process);GO:0005575(cellular_component);GO:0005575(cellular_component)","NA","NA","NA","zinc finger protein 688 [Source:HGNC Symbol;Acc:HGNC:30489]",{"v":0.750322796890506,"d":"0.75"},{"v":2.80273003241813,"d":"2.80"},{"v":0.267711405740761,"d":"0.27"},{"v":-1.9012494891358,"d":"-1.90"},{"v":1.85727269401023E-3,"d":"0.00"},{"v":0.108384461284125,"d":"0.11"},"down","yes"]
["ENSG00000183495","EP400","ENST00000389561;ENST00000611118;ENST00000333577;ENST00000616136;ENST00000611841;ENST00000332482;ENST00000389562;ENST00000611739;ENST00000330386","GO:0005634(nucleus);GO:0016607(nuclear speck);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0016787(hydrolase activity);GO:0016569(covalent chromatin modification);GO:0004386(helicase activity);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0005654(nucleoplasm);GO:0043967(histone H4 acetylation);GO:0043968(histone H2A acetylation);GO:0035267(NuA4 histone acetyltransferase complex);GO:0000812(Swr1 complex);GO:0003682(chromatin binding);GO:1990405(protein antigen binding);GO:1990405(protein antigen binding)","NA","NA","NA","E1A binding protein p400 [Source:HGNC Symbol;Acc:HGNC:11958]",{"v":3.01400413958835,"d":"3.01"},{"v":0.572860048436247,"d":"0.57"},{"v":5.26132717374124,"d":"5.26"},{"v":2.39542676633534,"d":"2.40"},{"v":1.87035846185977E-3,"d":"0.00"},{"v":0.108602364087887,"d":"0.11"},"up","yes"]
["ENSG00000158321","AUTS2","ENST00000416482;ENST00000476695;ENST00000481994;ENST00000449547;ENST00000615871;ENST00000342771;ENST00000483297;ENST00000418686;ENST00000465899;ENST00000498384;ENST00000403018;ENST00000406775;ENST00000464768;ENST00000489774;ENST00000611706","GO:0003674(molecular_function);GO:0008150(biological_process);GO:0005575(cellular_component);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0003682(chromatin binding);GO:0051571(positive regulation of histone H3-K4 methylation);GO:2000620(positive regulation of histone H4-K16 acetylation);GO:0060013(righting reflex);GO:0098582(innate vocalization behavior);GO:0005634(nucleus);GO:0005634(nucleus)","NA","NA","NA","AUTS2, activator of transcription and developmental regulator [Source:HGNC Symbol;Acc:HGNC:14262]",{"v":1.33640610902111,"d":"1.34"},{"v":0.247371514299424,"d":"0.25"},{"v":5.40242522590331,"d":"5.40"},{"v":2.43360719911347,"d":"2.43"},{"v":0.00193738380624521,"d":"0.00"},{"v":0.111934518119033,"d":"0.11"},"up","yes"]
["ENSG00000130193","THEM6","ENST00000336138;ENST00000518798","GO:0005576(extracellular region);GO:0005576(extracellular region)","NA","NA","NA","thioesterase superfamily member 6 [Source:HGNC Symbol;Acc:HGNC:29656]",{"v":1.87300301996727,"d":"1.87"},{"v":0.340506876268412,"d":"0.34"},{"v":5.50063200042643,"d":"5.50"},{"v":2.45959738800073,"d":"2.46"},{"v":1.99895180002359E-3,"d":"0.00"},{"v":0.114600871807078,"d":"0.11"},"up","yes"]
["MSTRG.12465","CCDC69","ENST00000355417;ENST00000519448;ENST00000518189;MSTRG.12465.1;ENST00000519740;ENST00000522179;ENST00000524344;ENST00000521308;ENST00000522964","GO:0005737(cytoplasm);GO:0005856(cytoskeleton);GO:0005819(spindle);GO:0030496(midbody);GO:0051255(spindle midzone assembly);GO:0051233(spindle midzone);GO:0051233(spindle midzone)","NA","NA","NA","coiled-coil domain containing 69 [Source:HGNC Symbol;Acc:HGNC:24487]",{"v":5.07780856125177,"d":"5.08"},{"v":18.1046195198931,"d":"18.10"},{"v":0.28047032723733,"d":"0.28"},{"v":-1.83407994798192,"d":"-1.83"},{"v":0.00200636584789226,"d":"0.00"},{"v":0.114600871807078,"d":"0.11"},"down","yes"]
["MSTRG.7299","CBX4","ENST00000269397;ENST00000448310;ENST00000494546;ENST00000495122","GO:0005634(nucleus);GO:0016607(nuclear speck);GO:0005654(nucleoplasm);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0016569(covalent chromatin modification);GO:0016874(ligase activity);GO:0005515(protein binding);GO:0016604(nuclear body);GO:0003682(chromatin binding);GO:0003727(single-stranded RNA binding);GO:0032183(SUMO binding);GO:0035064(methylated histone binding);GO:0044212(transcription regulatory region DNA binding);GO:0051219(phosphoprotein binding);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0016925(protein sumoylation);GO:0019899(enzyme binding);GO:0045892(negative regulation of transcription, DNA-templated);GO:0003714(transcription corepressor activity);GO:0019789(SUMO transferase activity);GO:0043066(negative regulation of apoptotic process);GO:0031519(PcG protein complex);GO:0035102(PRC1 complex);GO:0035102(PRC1 complex)","NA","NA","NA","chromobox 4 [Source:HGNC Symbol;Acc:HGNC:1554]",{"v":1.36758314444444,"d":"1.37"},{"v":4.97049369583333,"d":"4.97"},{"v":0.275140303586112,"d":"0.28"},{"v":-1.86176060835974,"d":"-1.86"},{"v":0.00201313853858985,"d":"0.00"},{"v":0.114600871807078,"d":"0.11"},"down","yes"]
["ENSG00000049618","ARID1B","ENST00000350026;ENST00000636205;ENST00000636909;ENST00000637015;ENST00000400790;ENST00000637532;ENST00000637810;ENST00000636930;ENST00000635849;ENST00000637722;ENST00000637887;ENST00000636426;ENST00000636940;ENST00000636254;ENST00000635957;ENST00000452544;ENST00000493658;ENST00000636227;ENST00000638000;ENST00000319584;ENST00000637933;ENST00000637910;ENST00000346085;ENST00000637548;ENST00000414678;ENST00000636748;ENST00000637170","GO:0005634(nucleus);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0016569(covalent chromatin modification);GO:0003677(DNA binding);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0007399(nervous system development);GO:0003713(transcription coactivator activity);GO:0006338(chromatin remodeling);GO:0090544(BAF-type complex);GO:0048096(chromatin-mediated maintenance of transcription);GO:0016514(SWI/SNF complex);GO:0007270(neuron-neuron synaptic transmission);GO:0060996(dendritic spine development);GO:0097026(dendritic cell dendrite assembly);GO:0071565(nBAF complex);GO:0071565(nBAF complex)","05225(Hepatocellular carcinoma);05225(Hepatocellular carcinoma)","K11653","NA","AT-rich interaction domain 1B [Source:HGNC Symbol;Acc:HGNC:18040]",{"v":1.38419810397658,"d":"1.38"},{"v":0.265296567343048,"d":"0.27"},{"v":5.2175499963658,"d":"5.22"},{"v":2.38337251985342,"d":"2.38"},{"v":0.0020264202544159,"d":"0.00"},{"v":0.114794236168448,"d":"0.11"},"up","yes"]
["MSTRG.9217","CERS6","ENST00000305747;ENST00000392687","GO:0005634(nucleus);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0003677(DNA binding);GO:0006629(lipid metabolic process);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0031965(nuclear membrane);GO:0030148(sphingolipid biosynthetic process);GO:0046513(ceramide biosynthetic process);GO:0050291(sphingosine N-acyltransferase activity);GO:0050291(sphingosine N-acyltransferase activity)","00600(Sphingolipid metabolism);04071(Sphingolipid signaling pathway);04071(Sphingolipid signaling pathway)","K04710","EC:2.3.1.24","ceramide synthase 6 [Source:HGNC Symbol;Acc:HGNC:23826]",{"v":3.85173811614418,"d":"3.85"},{"v":0.74145032067394,"d":"0.74"},{"v":5.1948701197447,"d":"5.19"},{"v":2.37708767984314,"d":"2.38"},{"v":2.07884616432836E-3,"d":"0.00"},{"v":0.116954732312208,"d":"0.12"},"up","yes"]
["ENSG00000184860","SDR42E1","ENST00000532128;ENST00000534209;ENST00000328945","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0003854(3-beta-hydroxy-delta5-steroid dehydrogenase activity);GO:0016616(oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor);GO:0006694(steroid biosynthetic process);GO:0006694(steroid biosynthetic process)","NA","NA","NA","short chain dehydrogenase/reductase family 42E, member 1 [Source:HGNC Symbol;Acc:HGNC:29834]",{"v":0.507774017294938,"d":"0.51"},{"v":0.0929066644278398,"d":"0.09"},{"v":5.46542081154279,"d":"5.47"},{"v":2.45033258086576,"d":"2.45"},{"v":2.08470073095902E-3,"d":"0.00"},{"v":0.116954732312208,"d":"0.12"},"up","yes"]
["MSTRG.13522","TOMM7","ENST00000358435;ENST00000621567;ENST00000372879;ENST00000483581;ENST00000405021;ENST00000496129;ENST00000463284","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0015031(protein transport);GO:0005739(mitochondrion);GO:0005515(protein binding);GO:0005741(mitochondrial outer membrane);GO:0005742(mitochondrial outer membrane translocase complex);GO:0030150(protein import into mitochondrial matrix);GO:1903955(positive regulation of protein targeting to mitochondrion);GO:0015266(protein channel activity);GO:0016236(macroautophagy);GO:0031647(regulation of protein stability);GO:0098779(positive regulation of macromitophagy in response to mitochondrial depolarization);GO:0008320(protein transmembrane transporter activity);GO:0006626(protein targeting to mitochondrion);GO:0031307(integral component of mitochondrial outer membrane);GO:0045040(protein import into mitochondrial outer membrane);GO:0045040(protein import into mitochondrial outer membrane)","04137(Mitophagy - animal);04137(Mitophagy - animal)","K17771","NA","translocase of outer mitochondrial membrane 7 [Source:HGNC Symbol;Acc:HGNC:21648]",{"v":13.2337556373501,"d":"13.23"},{"v":46.7705327030268,"d":"46.77"},{"v":0.282950714317899,"d":"0.28"},{"v":-1.82137731533348,"d":"-1.82"},{"v":0.00213448093538636,"d":"0.00"},{"v":0.119171764916547,"d":"0.12"},"down","yes"]
["MSTRG.9645","PLAGL2","ENST00000246229","GO:0005634(nucleus);GO:0003676(nucleic acid binding);GO:0046872(metal ion binding);GO:0006366(transcription from RNA polymerase II promoter);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0006915(apoptotic process);GO:1903955(positive regulation of protein targeting to mitochondrion);GO:0043565(sequence-specific DNA binding);GO:0001077(transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0006629(lipid metabolic process);GO:0009791(post-embryonic development);GO:0034378(chylomicron assembly);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:2001244(positive regulation of intrinsic apoptotic signaling pathway)","NA","NA","NA","PLAG1 like zinc finger 2 [Source:HGNC Symbol;Acc:HGNC:9047]",{"v":7.278008,"d":"7.28"},{"v":1.414677,"d":"1.41"},{"v":5.14464291142077,"d":"5.14"},{"v":2.36307094343588,"d":"2.36"},{"v":0.00216908068492487,"d":"0.00"},{"v":0.12052408609585,"d":"0.12"},"up","yes"]
["MSTRG.13781","LMTK2","ENST00000297293;ENST00000493372","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005829(cytosol);GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0005794(Golgi apparatus);GO:0005515(protein binding);GO:0043086(negative regulation of catalytic activity);GO:0048471(perinuclear region of cytoplasm);GO:0004864(protein phosphatase inhibitor activity);GO:0005769(early endosome);GO:0055037(recycling endosome);GO:0046777(protein autophosphorylation);GO:0018107(peptidyl-threonine phosphorylation);GO:0032456(endocytic recycling);GO:0018105(peptidyl-serine phosphorylation);GO:0033572(transferrin transport);GO:0045022(early endosome to late endosome transport);GO:0001881(receptor recycling);GO:0070853(myosin VI binding);GO:0030426(growth cone);GO:0043025(neuronal cell body);GO:0043025(neuronal cell body)","NA","NA","NA","lemur tyrosine kinase 2 [Source:HGNC Symbol;Acc:HGNC:17880]",{"v":5.21032307473465,"d":"5.21"},{"v":1.01518610460663,"d":"1.02"},{"v":5.13238218203703,"d":"5.13"},{"v":2.35962860448841,"d":"2.36"},{"v":0.00221497312924505,"d":"0.00"},{"v":0.122488014047251,"d":"0.12"},"up","yes"]
["MSTRG.12786","HLA-F-AS1;MCCD1P1","MSTRG.12786.1;MSTRG.12786.2","NA","NA","NA","NA",null,{"v":9.57562933333333,"d":"9.58"},{"v":34.0012845271318,"d":"34.00"},{"v":0.28162551699164,"d":"0.28"},{"v":-1.82815003800912,"d":"-1.83"},{"v":0.00224305873921848,"d":"0.00"},{"v":0.123453275538124,"d":"0.12"},"down","yes"]
["MSTRG.3410","COPZ1","MSTRG.3410.2;ENST00000262061;ENST00000550171;ENST00000552218;ENST00000550713;ENST00000551412;ENST00000548753;ENST00000550027;MSTRG.3410.1;ENST00000553231;ENST00000553009;ENST00000549116;ENST00000548281;ENST00000549043;ENST00000552362;ENST00000455864;ENST00000551779","GO:0006810(transport);GO:0006886(intracellular protein transport);GO:0015031(protein transport);GO:0016192(vesicle-mediated transport);GO:0030117(membrane coat);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005794(Golgi apparatus);GO:0000139(Golgi membrane);GO:0031410(cytoplasmic vesicle);GO:0030663(COPI-coated vesicle membrane);GO:0005789(endoplasmic reticulum membrane);GO:0005829(cytosol);GO:0006890(retrograde vesicle-mediated transport, Golgi to ER);GO:0006888(ER to Golgi vesicle-mediated transport);GO:0030133(transport vesicle);GO:0006891(intra-Golgi vesicle-mediated transport);GO:0030126(COPI vesicle coat);GO:1901998(toxin transport);GO:1901998(toxin transport)","NA","NA","NA","coatomer protein complex subunit zeta 1 [Source:HGNC Symbol;Acc:HGNC:2243]",{"v":4.26747163239401,"d":"4.27"},{"v":14.9984862221376,"d":"15.00"},{"v":0.284526822853314,"d":"0.28"},{"v":-1.8133634304983,"d":"-1.81"},{"v":0.00226536733743144,"d":"0.00"},{"v":0.124092975894299,"d":"0.12"},"down","yes"]
["ENSG00000196367","TRRAP","ENST00000359863;ENST00000628380;ENST00000417523;ENST00000355540;ENST00000456197","GO:0005634(nucleus);GO:0005794(Golgi apparatus);GO:0005654(nucleoplasm);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0016569(covalent chromatin modification);GO:0016301(kinase activity);GO:0005515(protein binding);GO:0000123(histone acetyltransferase complex);GO:0016310(phosphorylation);GO:0016578(histone deubiquitination);GO:0016573(histone acetylation);GO:0016579(protein deubiquitination);GO:0043967(histone H4 acetylation);GO:1904837(beta-catenin-TCF complex assembly);GO:0033276(transcription factor TFTC complex);GO:0003712(transcription cofactor activity);GO:0036459(thiol-dependent ubiquitinyl hydrolase activity);GO:0006281(DNA repair);GO:0000125(PCAF complex);GO:0030914(STAGA complex);GO:0043968(histone H2A acetylation);GO:0035267(NuA4 histone acetyltransferase complex);GO:0000812(Swr1 complex);GO:0016740(transferase activity);GO:0016740(transferase activity)","05166(HTLV-I infection);05166(HTLV-I infection)","K08874","NA","transformation/transcription domain associated protein [Source:HGNC Symbol;Acc:HGNC:12347]",{"v":5.48105767551823,"d":"5.48"},{"v":1.07923497889242,"d":"1.08"},{"v":5.07865088022188,"d":"5.08"},{"v":2.34444530272335,"d":"2.34"},{"v":0.00230651572275281,"d":"0.00"},{"v":0.125753836095438,"d":"0.13"},"up","yes"]
["MSTRG.10977","GLYCTK","ENST00000471180;ENST00000489173;ENST00000461183;ENST00000473032;ENST00000477382;ENST00000473583;ENST00000305690;ENST00000486393;ENST00000436784","GO:0005794(Golgi apparatus);GO:0005829(cytosol);GO:0005737(cytoplasm);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0005739(mitochondrion);GO:0005515(protein binding);GO:0006468(protein phosphorylation);GO:0061624(fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate);GO:0008887(glycerate kinase activity);GO:0008887(glycerate kinase activity)","00030(Pentose phosphate pathway);00630(Glyoxylate and dicarboxylate metabolism);00561(Glycerolipid metabolism);00260(Glycine, serine and threonine metabolism);00260(Glycine, serine and threonine metabolism)","K11529","EC:2.7.1.165","glycerate kinase [Source:HGNC Symbol;Acc:HGNC:24247]",{"v":0.924153600730169,"d":"0.92"},{"v":3.31178317092599,"d":"3.31"},{"v":0.279050153054486,"d":"0.28"},{"v":-1.84140365720404,"d":"-1.84"},{"v":2.34079873210302E-3,"d":"0.00"},{"v":0.126626373648069,"d":"0.13"},"down","yes"]
["MSTRG.7310","RNF213;AC124319.4","ENST00000582970;ENST00000508628;ENST00000411702;ENST00000319921;ENST00000573038;ENST00000572622;ENST00000560083;ENST00000560694;ENST00000559864;ENST00000574060;ENST00000571908;ENST00000570776;ENST00000622931;ENST00000427003;ENST00000559603;ENST00000574909;ENST00000559070;ENST00000573919;ENST00000558488","GO:0046872(metal ion binding);GO:0005730(nucleolus);GO:0005829(cytosol);GO:0016567(protein ubiquitination);GO:0004842(ubiquitin-protein transferase activity);GO:0016887(ATPase activity);GO:0001525(angiogenesis);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0016740(transferase activity);GO:0016787(hydrolase activity);GO:0006511(ubiquitin-dependent protein catabolic process);GO:0002040(sprouting angiogenesis);GO:0000209(protein polyubiquitination);GO:0051260(protein homooligomerization);GO:0051865(protein autoubiquitination);GO:2000051(negative regulation of non-canonical Wnt signaling pathway);GO:2000051(negative regulation of non-canonical Wnt signaling pathway)","NA","NA","NA","ring finger protein 213 [Source:HGNC Symbol;Acc:HGNC:14539]",{"v":18.4940628395217,"d":"18.49"},{"v":3.66078991232822,"d":"3.66"},{"v":5.05193231035749,"d":"5.05"},{"v":2.33683530892638,"d":"2.34"},{"v":2.3443270760643E-3,"d":"0.00"},{"v":0.126626373648069,"d":"0.13"},"up","yes"]
["MSTRG.67","SKI","ENST00000378536;ENST00000478223;ENST00000507179;ENST00000508416","GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0005737(cytoplasm);GO:0048147(negative regulation of fibroblast proliferation);GO:0007179(transforming growth factor beta receptor signaling pathway);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0008270(zinc ion binding);GO:0006351(transcription, DNA-templated);GO:0005515(protein binding);GO:0016604(nuclear body);GO:0046332(SMAD binding);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0003714(transcription corepressor activity);GO:0019901(protein kinase binding);GO:0008285(negative regulation of cell proliferation);GO:0031625(ubiquitin protein ligase binding);GO:0043234(protein complex);GO:0005667(transcription factor complex);GO:0019904(protein domain specific binding);GO:0030509(BMP signaling pathway);GO:0070491(repressing transcription factor binding);GO:0016605(PML body);GO:0060395(SMAD protein signal transduction);GO:0060021(palate development);GO:0030177(positive regulation of Wnt signaling pathway);GO:0001843(neural tube closure);GO:0005813(centrosome);GO:0022011(myelination in peripheral nervous system);GO:0030512(negative regulation of transforming growth factor beta receptor signaling pathway);GO:0017053(transcriptional repressor complex);GO:0030514(negative regulation of BMP signaling pathway);GO:0045668(negative regulation of osteoblast differentiation);GO:0043388(positive regulation of DNA binding);GO:0060349(bone morphogenesis);GO:0032926(negative regulation of activin receptor signaling pathway);GO:0009948(anterior/posterior axis specification);GO:0008283(cell proliferation);GO:0043585(nose morphogenesis);GO:0060325(face morphogenesis);GO:0070207(protein homotrimerization);GO:0030326(embryonic limb morphogenesis);GO:0046811(histone deacetylase inhibitor activity);GO:0002089(lens morphogenesis in camera-type eye);GO:0010626(negative regulation of Schwann cell proliferation);GO:0014902(myotube differentiation);GO:0021772(olfactory bulb development);GO:0031064(negative regulation of histone deacetylation);GO:0035019(somatic stem cell population maintenance);GO:0043010(camera-type eye development);GO:0048593(camera-type eye morphogenesis);GO:0048666(neuron development);GO:0048741(skeletal muscle fiber development);GO:0048870(cell motility);GO:0060041(retina development in camera-type eye);GO:0060041(retina development in camera-type eye)","NA","NA","NA","SKI proto-oncogene [Source:HGNC Symbol;Acc:HGNC:10896]",{"v":7.42562105953947,"d":"7.43"},{"v":1.46302895888158,"d":"1.46"},{"v":5.07551201530284,"d":"5.08"},{"v":2.34355336804719,"d":"2.34"},{"v":2.36782091150278E-3,"d":"0.00"},{"v":0.127303260394823,"d":"0.13"},"up","yes"]
["ENSG00000176542","USF3","ENST00000316407;ENST00000496826;ENST00000478658","GO:0046983(protein dimerization activity);GO:0005634(nucleus);GO:0003677(DNA binding);GO:0005783(endoplasmic reticulum);GO:0000139(Golgi membrane);GO:0004571(mannosyl-oligosaccharide 1,2-alpha-mannosidase activity);GO:0006491(N-glycan processing);GO:0006491(N-glycan processing)","NA","NA","NA","upstream transcription factor family member 3 [Source:HGNC Symbol;Acc:HGNC:30494]",{"v":3.72146650101907,"d":"3.72"},{"v":0.734666180812345,"d":"0.73"},{"v":5.06552036586756,"d":"5.07"},{"v":2.34071048041736,"d":"2.34"},{"v":0.00238215664598755,"d":"0.00"},{"v":0.127483802441721,"d":"0.13"},"up","yes"]
["ENSG00000181894","ZNF329","ENST00000597186;ENST00000601887;ENST00000500161;ENST00000598312","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0005515(protein binding)","NA","NA","NA","zinc finger protein 329 [Source:HGNC Symbol;Acc:HGNC:14209]",{"v":1.24957062450685,"d":"1.25"},{"v":0.231890359944303,"d":"0.23"},{"v":5.38862687007334,"d":"5.39"},{"v":2.42991769225154,"d":"2.43"},{"v":0.00241068003529605,"d":"0.00"},{"v":0.128418473623362,"d":"0.13"},"up","yes"]
["ENSG00000196498","NCOR2","ENST00000404621;ENST00000405201;ENST00000356219;ENST00000458234;ENST00000429285;ENST00000473999;ENST00000461081;ENST00000440187;ENST00000464377;ENST00000440337;ENST00000542927;ENST00000474079;ENST00000418829;ENST00000493859;ENST00000453428;ENST00000404121;ENST00000448614;ENST00000494460;ENST00000542565;ENST00000443451;ENST00000448008","GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0003677(DNA binding);GO:0001012(RNA polymerase II regulatory region DNA binding);GO:0003682(chromatin binding);GO:0016922(ligand-dependent nuclear receptor binding);GO:0032403(protein complex binding);GO:0035259(glucocorticoid receptor binding);GO:0042974(retinoic acid receptor binding);GO:0046965(retinoid X receptor binding);GO:0007595(lactation);GO:0010243(response to organonitrogen compound);GO:0032355(response to estradiol);GO:0044849(estrous cycle);GO:0000785(chromatin);GO:0016020(membrane);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0005515(protein binding);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0003714(transcription corepressor activity);GO:0008134(transcription factor binding);GO:0047485(protein N-terminus binding);GO:0000790(nuclear chromatin);GO:0016363(nuclear matrix);GO:0005112(Notch binding);GO:0042826(histone deacetylase binding);GO:0019216(regulation of lipid metabolic process);GO:0017053(transcriptional repressor complex);GO:1903799(negative regulation of production of miRNAs involved in gene silencing by miRNA);GO:0000118(histone deacetylase complex);GO:0072365(regulation of cellular ketone metabolic process by negative regulation of transcription from RNA polymerase II promoter);GO:0016604(nuclear body);GO:0016604(nuclear body)","04330(Notch signaling pathway);05169(Epstein-Barr virus infection);05169(Epstein-Barr virus infection)","K06065","NA","nuclear receptor corepressor 2 [Source:HGNC Symbol;Acc:HGNC:7673]",{"v":5.05743470661896,"d":"5.06"},{"v":1.00453724636852,"d":"1.00"},{"v":5.03459152450741,"d":"5.03"},{"v":2.33187473166341,"d":"2.33"},{"v":2.44932016704992E-3,"d":"0.00"},{"v":0.129881073515757,"d":"0.13"},"up","yes"]
["ENSG00000141026","MED9","ENST00000268711;ENST00000585041;ENST00000624097;ENST00000580462","GO:0005634(nucleus);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0001104(RNA polymerase II transcription cofactor activity);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0016592(mediator complex);GO:0005515(protein binding);GO:0005515(protein binding)","NA","NA","NA","mediator complex subunit 9 [Source:HGNC Symbol;Acc:HGNC:25487]",{"v":1.04295910386796,"d":"1.04"},{"v":0.195950784094698,"d":"0.20"},{"v":5.32255641990146,"d":"5.32"},{"v":2.41211933754382,"d":"2.41"},{"v":2.46708642705695E-3,"d":"0.00"},{"v":0.130228521260965,"d":"0.13"},"up","yes"]
["ENSG00000144827","ABHD10","ENST00000273359;ENST00000493784;ENST00000494817;ENST00000497293;ENST00000491580","GO:0016787(hydrolase activity);GO:0005739(mitochondrion);GO:0005759(mitochondrial matrix);GO:0005829(cytosol);GO:0052695(cellular glucuronidation);GO:0004553(hydrolase activity, hydrolyzing O-glycosyl compounds);GO:0102390(mycophenolic acid acyl-glucuronide esterase activity);GO:0019391(glucuronoside catabolic process);GO:0019391(glucuronoside catabolic process)","NA","NA","NA","abhydrolase domain containing 10 [Source:HGNC Symbol;Acc:HGNC:25656]",{"v":1.1182640877193,"d":"1.12"},{"v":3.94090076001324,"d":"3.94"},{"v":0.283758499850055,"d":"0.28"},{"v":-1.81726448659708,"d":"-1.82"},{"v":0.00249152849673168,"d":"0.00"},{"v":0.13092362186672,"d":"0.13"},"down","yes"]
["MSTRG.2489","RTN3","ENST00000341307;ENST00000537981;ENST00000543552;ENST00000540798;ENST00000339997;ENST00000338850;ENST00000538995;ENST00000536011;ENST00000356000;ENST00000377819;ENST00000543123;ENST00000542238","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005783(endoplasmic reticulum);GO:0005794(Golgi apparatus);GO:0005789(endoplasmic reticulum membrane);GO:0005515(protein binding);GO:0006915(apoptotic process);GO:0000139(Golgi membrane);GO:0005886(plasma membrane);GO:0016192(vesicle-mediated transport);GO:0070062(extracellular exosome);GO:0016032(viral process);GO:0005615(extracellular space);GO:0071786(endoplasmic reticulum tubular network organization);GO:0071787(endoplasmic reticulum tubular network formation);GO:0071787(endoplasmic reticulum tubular network formation)","05010(Alzheimer's disease);05010(Alzheimer's disease)","K20723","NA","reticulon 3 [Source:HGNC Symbol;Acc:HGNC:10469]",{"v":32.4202537427486,"d":"32.42"},{"v":6.48105506457182,"d":"6.48"},{"v":5.00231110825942,"d":"5.00"},{"v":2.32259478570473,"d":"2.32"},{"v":0.00252694869664394,"d":"0.00"},{"v":0.132186735198766,"d":"0.13"},"up","yes"]
["ENSG00000167747","C19orf48","ENST00000641834;ENST00000597493;ENST00000598463;ENST00000601267;ENST00000596554;ENST00000391812;ENST00000593287;ENST00000596655;ENST00000596287;ENST00000641539;ENST00000595794;ENST00000345523","NA","NA","NA","NA","chromosome 19 open reading frame 48 [Source:HGNC Symbol;Acc:HGNC:29667]",{"v":0.590602285626536,"d":"0.59"},{"v":2.11344948280098,"d":"2.11"},{"v":0.279449445294431,"d":"0.28"},{"v":-1.83934078362531,"d":"-1.84"},{"v":2.5396063241627E-3,"d":"0.00"},{"v":0.132253131132294,"d":"0.13"},"down","yes"]
["ENSG00000162139","NEU3","ENST00000526068;ENST00000294064;ENST00000531619;ENST00000531509;ENST00000529024;ENST00000534628","GO:0016020(membrane);GO:0016787(hydrolase activity);GO:0006629(lipid metabolic process);GO:0016042(lipid catabolic process);GO:0005886(plasma membrane);GO:0008152(metabolic process);GO:0016798(hydrolase activity, acting on glycosyl bonds);GO:0004308(exo-alpha-sialidase activity);GO:0005975(carbohydrate metabolic process);GO:0005737(cytoplasm);GO:0006687(glycosphingolipid metabolic process);GO:0005887(integral component of plasma membrane);GO:0043231(intracellular membrane-bounded organelle);GO:0052794(exo-alpha-(2->3)-sialidase activity);GO:0052795(exo-alpha-(2->6)-sialidase activity);GO:0052796(exo-alpha-(2->8)-sialidase activity);GO:0006689(ganglioside catabolic process);GO:0009313(oligosaccharide catabolic process);GO:0016997(alpha-sialidase activity);GO:0016997(alpha-sialidase activity)","00600(Sphingolipid metabolism);00511(Other glycan degradation);00511(Other glycan degradation)","K12357","EC:3.2.1.18","neuraminidase 3 [Source:HGNC Symbol;Acc:HGNC:7760]",{"v":1.02289751561673,"d":"1.02"},{"v":0.193888389359449,"d":"0.19"},{"v":5.27570278445288,"d":"5.28"},{"v":2.39936329023881,"d":"2.40"},{"v":0.00255829733508055,"d":"0.00"},{"v":0.132631727465582,"d":"0.13"},"up","yes"]
["MSTRG.4381","NIN","ENST00000245441;ENST00000382043;ENST00000530853;ENST00000463419;ENST00000453196;ENST00000474937;ENST00000480476;ENST00000555984;ENST00000496749;ENST00000476352;ENST00000324330;ENST00000382041;ENST00000486200;ENST00000389869;ENST00000486950;MSTRG.4381.1;ENST00000530997;ENST00000453401","GO:0005509(calcium ion binding);GO:0005813(centrosome);GO:0034454(microtubule anchoring at centrosome);GO:0005737(cytoplasm);GO:0000166(nucleotide binding);GO:0005634(nucleus);GO:0005730(nucleolus);GO:0005525(GTP binding);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0005874(microtubule);GO:0005815(microtubule organizing center);GO:0005814(centriole);GO:0097539(ciliary transition fiber);GO:0000922(spindle pole);GO:0000242(pericentriolar material);GO:0051642(centrosome localization);GO:0090222(centrosome-templated microtubule nucleation);GO:0036449(microtubule minus-end);GO:0097431(mitotic spindle pole);GO:0097431(mitotic spindle pole)","NA","NA","NA","ninein [Source:HGNC Symbol;Acc:HGNC:14906]",{"v":15.5872493502887,"d":"15.59"},{"v":3.12494833552583,"d":"3.12"},{"v":4.98800225689679,"d":"4.99"},{"v":2.31846211793684,"d":"2.32"},{"v":0.00257020144448622,"d":"0.00"},{"v":0.132656663888082,"d":"0.13"},"up","yes"]
["ENSG00000149346","SLX4IP","ENST00000334534;ENST00000488816","GO:0005515(protein binding);GO:0005515(protein binding)","NA","NA","NA","SLX4 interacting protein [Source:HGNC Symbol;Acc:HGNC:16225]",{"v":0.122545313308688,"d":"0.12"},{"v":0.458709074861368,"d":"0.46"},{"v":0.267152581068347,"d":"0.27"},{"v":-1.90426413920331,"d":"-1.90"},{"v":0.00258658942830727,"d":"0.00"},{"v":0.132911783322709,"d":"0.13"},"down","yes"]
["MSTRG.3720","SH2B3","ENST00000341259;ENST00000550925;ENST00000538307","GO:0035556(intracellular signal transduction);GO:0007165(signal transduction);GO:0004871(signal transducer activity);GO:0035591(signaling adaptor activity);GO:0009967(positive regulation of signal transduction);GO:0005515(protein binding);GO:0030097(hemopoiesis);GO:0005829(cytosol);GO:0007596(blood coagulation);GO:0030154(cell differentiation);GO:0035162(embryonic hemopoiesis);GO:0035162(embryonic hemopoiesis)","04722(Neurotrophin signaling pathway);04722(Neurotrophin signaling pathway)","K12459","NA","SH2B adaptor protein 3 [Source:HGNC Symbol;Acc:HGNC:29605]",{"v":17.5717081425554,"d":"17.57"},{"v":3.5320967124252,"d":"3.53"},{"v":4.97486608470875,"d":"4.97"},{"v":2.31465769117853,"d":"2.31"},{"v":0.00262467275850284,"d":"0.00"},{"v":0.134143549245411,"d":"0.13"},"up","yes"]
["MSTRG.15124","TPRN;TMEM203","ENST00000409012;ENST00000541945;ENST00000333046;ENST00000477345;ENST00000343666","GO:0007605(sensory perception of sound);GO:0019902(phosphatase binding);GO:0042995(cell projection);GO:0005515(protein binding);GO:0003674(molecular_function);GO:0032420(stereocilium);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0007283(spermatogenesis);GO:0006874(cellular calcium ion homeostasis)","NA","NA","NA","taperin [Source:HGNC Symbol;Acc:HGNC:26894];transmembrane protein 203 [Source:HGNC Symbol;Acc:HGNC:28217]",{"v":0.401226239676708,"d":"0.40"},{"v":1.39829040337987,"d":"1.40"},{"v":0.286940565927426,"d":"0.29"},{"v":-1.80117615283437,"d":"-1.80"},{"v":2.63366306965932E-3,"d":"0.00"},{"v":0.134143549245411,"d":"0.13"},"down","yes"]
["ENSG00000169871","TRIM56","ENST00000306085;ENST00000467847;ENST00000412507","GO:0046872(metal ion binding);GO:0008270(zinc ion binding);GO:0005622(intracellular);GO:0003723(RNA binding);GO:0005737(cytoplasm);GO:0016740(transferase activity);GO:0002376(immune system process);GO:0045087(innate immune response);GO:0051607(defense response to virus);GO:0005829(cytosol);GO:0004842(ubiquitin-protein transferase activity);GO:0070534(protein K63-linked ubiquitination);GO:0034340(response to type I interferon);GO:0032479(regulation of type I interferon production);GO:0032608(interferon-beta production);GO:0032608(interferon-beta production)","NA","NA","NA","tripartite motif containing 56 [Source:HGNC Symbol;Acc:HGNC:19028]",{"v":5.6867996483487,"d":"5.69"},{"v":1.14315586342075,"d":"1.14"},{"v":4.97464941598748,"d":"4.97"},{"v":2.31459485658327,"d":"2.31"},{"v":0.00265544725193566,"d":"0.00"},{"v":0.134662484439864,"d":"0.13"},"up","yes"]
["ENSG00000140836","ZFHX3","ENST00000641206;ENST00000641077;ENST00000358463","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0005654(nucleoplasm);GO:0046983(protein dimerization activity);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0043565(sequence-specific DNA binding);GO:0045893(positive regulation of transcription, DNA-templated);GO:0005515(protein binding);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:0001078(transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0007517(muscle organ development);GO:0019899(enzyme binding);GO:0006366(transcription from RNA polymerase II promoter);GO:0032922(circadian regulation of gene expression);GO:0005667(transcription factor complex);GO:0003705(transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding);GO:0001046(core promoter sequence-specific DNA binding);GO:0016604(nuclear body);GO:0071559(response to transforming growth factor beta);GO:1904059(regulation of locomotor rhythm);GO:0007050(cell cycle arrest);GO:0007420(brain development);GO:0045664(regulation of neuron differentiation);GO:0045664(regulation of neuron differentiation)","04550(Signaling pathways regulating pluripotency of stem cells);04550(Signaling pathways regulating pluripotency of stem cells)","NA","NA","zinc finger homeobox 3 [Source:HGNC Symbol;Acc:HGNC:777]",{"v":0.612051992709968,"d":"0.61"},{"v":0.120563352908419,"d":"0.12"},{"v":5.07660062485893,"d":"5.08"},{"v":2.34386276800555,"d":"2.34"},{"v":2.69935534943177E-3,"d":"0.00"},{"v":0.136293972491092,"d":"0.14"},"up","yes"]
["MSTRG.3422","ZNF385A","ENST00000394313;ENST00000549937;ENST00000550779;ENST00000549962;ENST00000338010;ENST00000551109;ENST00000352268;ENST00000551771;ENST00000546919;ENST00000550120;ENST00000546970;ENST00000550774","GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0000790(nuclear chromatin);GO:0042995(cell projection);GO:0006974(cellular response to DNA damage stimulus);GO:0006915(apoptotic process);GO:0005730(nucleolus);GO:0030425(dendrite);GO:0006977(DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest);GO:0005654(nucleoplasm);GO:0006417(regulation of translation);GO:0003730(mRNA 3'-UTR binding);GO:1901796(regulation of signal transduction by p53 class mediator);GO:0002039(p53 binding);GO:0043025(neuronal cell body);GO:0045600(positive regulation of fat cell differentiation);GO:0035855(megakaryocyte development);GO:2000765(regulation of cytoplasmic translation);GO:0010609(mRNA localization resulting in posttranscriptional regulation of gene expression);GO:1902164(positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator);GO:1902166(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator);GO:0007599(hemostasis);GO:0007611(learning or memory);GO:0007626(locomotory behavior);GO:0008298(intracellular mRNA localization);GO:0030220(platelet formation);GO:0070889(platelet alpha granule organization);GO:0070889(platelet alpha granule organization)","NA","NA","NA","zinc finger protein 385A [Source:HGNC Symbol;Acc:HGNC:17521]",{"v":11.5937222953759,"d":"11.59"},{"v":2.33147916388802,"d":"2.33"},{"v":4.97268964481844,"d":"4.97"},{"v":2.31402639256165,"d":"2.31"},{"v":0.00271380568609934,"d":"0.00"},{"v":0.136430413128449,"d":"0.14"},"up","yes"]
["ENSG00000131016","AKAP12","ENST00000253332;ENST00000354675;ENST00000402676","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005829(cytosol);GO:0006605(protein targeting);GO:0007165(signal transduction);GO:0005886(plasma membrane);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0005925(focal adhesion);GO:0005938(cell cortex);GO:0007186(G-protein coupled receptor signaling pathway);GO:0030819(positive regulation of cAMP biosynthetic process);GO:0051018(protein kinase A binding);GO:0008179(adenylate cyclase binding);GO:0010739(positive regulation of protein kinase A signaling);GO:0090036(regulation of protein kinase C signaling);GO:0090036(regulation of protein kinase C signaling)","NA","NA","NA","A-kinase anchoring protein 12 [Source:HGNC Symbol;Acc:HGNC:370]",{"v":0.556415176295618,"d":"0.56"},{"v":0.106264454867864,"d":"0.11"},{"v":5.23613636363636,"d":"5.24"},{"v":2.38850266958648,"d":"2.39"},{"v":0.0027842841211848,"d":"0.00"},{"v":0.139370221979823,"d":"0.14"},"up","yes"]
["ENSG00000177426","TGIF1","ENST00000343820;ENST00000405385;ENST00000472042;ENST00000618001;ENST00000401449;ENST00000551333;ENST00000552383;ENST00000549780;ENST00000407501;ENST00000577543;ENST00000551402;ENST00000549253;ENST00000330513;ENST00000400167;ENST00000546979;ENST00000551541","GO:0005634(nucleus);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0005654(nucleoplasm);GO:0006351(transcription, DNA-templated);GO:0005515(protein binding);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:0001078(transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0007275(multicellular organism development);GO:0003714(transcription corepressor activity);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0070410(co-SMAD binding);GO:0010629(negative regulation of gene expression);GO:0042493(response to drug);GO:0071363(cellular response to growth factor stimulus);GO:0071363(cellular response to growth factor stimulus)","04350(TGF-beta signaling pathway);04350(TGF-beta signaling pathway)","K19383","NA","TGFB induced factor homeobox 1 [Source:HGNC Symbol;Acc:HGNC:11776]",{"v":0.530788431038677,"d":"0.53"},{"v":1.8267716723425,"d":"1.83"},{"v":0.290560905380166,"d":"0.29"},{"v":-1.78308749173896,"d":"-1.78"},{"v":0.00281778657977522,"d":"0.00"},{"v":0.140441869317295,"d":"0.14"},"down","yes"]
["ENSG00000171295","ZNF440","ENST00000414255;ENST00000588954;ENST00000457526;ENST00000427505;ENST00000587795;ENST00000304060","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0005622(intracellular);GO:0005515(protein binding);GO:0005515(protein binding)","NA","NA","NA","zinc finger protein 440 [Source:HGNC Symbol;Acc:HGNC:20874]",{"v":0.124533419480317,"d":"0.12"},{"v":0.458356473938074,"d":"0.46"},{"v":0.271695561339758,"d":"0.27"},{"v":-1.87993709828378,"d":"-1.88"},{"v":0.00294135073637481,"d":"0.00"},{"v":0.145973957698806,"d":"0.15"},"down","yes"]
["ENSG00000253882","AC099548.2","ENST00000481651;ENST00000494978;ENST00000491047;ENST00000463346;ENST00000480264;ENST00000517565;ENST00000471316","NA","NA","NA","NA",null,{"v":0.768412265931034,"d":"0.77"},{"v":2.67566502317241,"d":"2.68"},{"v":0.287185525570747,"d":"0.29"},{"v":-1.7999450571245,"d":"-1.80"},{"v":0.00297640547034093,"d":"0.00"},{"v":0.147085092455614,"d":"0.15"},"down","yes"]
["ENSG00000148773","MKI67","ENST00000368654;ENST00000484853;ENST00000368653;ENST00000478293","GO:0003723(RNA binding);GO:0005634(nucleus);GO:0016020(membrane);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0005730(nucleolus);GO:0003677(DNA binding);GO:0005694(chromosome);GO:0005515(protein binding);GO:0007049(cell cycle);GO:0016604(nuclear body);GO:0008283(cell proliferation);GO:0008022(protein C-terminus binding);GO:0007088(regulation of mitotic nuclear division);GO:0051983(regulation of chromosome segregation);GO:0000793(condensed chromosome);GO:1902275(regulation of chromatin organization);GO:0006259(DNA metabolic process);GO:0014070(response to organic cyclic compound);GO:0030212(hyaluronan metabolic process);GO:0031100(animal organ regeneration);GO:0034605(cellular response to heat);GO:0051321(meiotic cell cycle);GO:0000775(chromosome, centromeric region);GO:0005737(cytoplasm);GO:0005737(cytoplasm)","NA","NA","NA","marker of proliferation Ki-67 [Source:HGNC Symbol;Acc:HGNC:7107]",{"v":0.378527677676271,"d":"0.38"},{"v":0.0733437198407121,"d":"0.07"},{"v":5.1610100837312,"d":"5.16"},{"v":2.36765344940413,"d":"2.37"},{"v":0.00300214101248571,"d":"0.00"},{"v":0.147728235499985,"d":"0.15"},"up","yes"]
["MSTRG.8198","CIC","ENST00000572681;MSTRG.8198.5;ENST00000575354;ENST00000576505;ENST00000160740;MSTRG.8198.7;ENST00000573349;ENST00000571033;ENST00000575287;ENST00000571942","GO:0005634(nucleus);GO:0003677(DNA binding);GO:0043231(intracellular membrane-bounded organelle);GO:0005654(nucleoplasm);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0005515(protein binding);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0000122(negative regulation of transcription from RNA polymerase II promoter)","NA","NA","NA","capicua transcriptional repressor [Source:HGNC Symbol;Acc:HGNC:14214]",{"v":7.55026783326311,"d":"7.55"},{"v":1.54623544406994,"d":"1.55"},{"v":4.88300010339279,"d":"4.88"},{"v":2.28776780852304,"d":"2.29"},{"v":0.00302910121494218,"d":"0.00"},{"v":0.147882228740507,"d":"0.15"},"up","yes"]
["MSTRG.3332","SLC48A1","ENST00000442218;ENST00000547002;ENST00000476104","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0006810(transport);GO:0005765(lysosomal membrane);GO:0005515(protein binding);GO:0005764(lysosome);GO:0005768(endosome);GO:0010008(endosome membrane);GO:0015232(heme transporter activity);GO:0015886(heme transport);GO:0005886(plasma membrane);GO:0020037(heme binding);GO:0020037(heme binding)","NA","NA","NA","solute carrier family 48 member 1 [Source:HGNC Symbol;Acc:HGNC:26035]",{"v":1.74908582503556,"d":"1.75"},{"v":0.348761099370047,"d":"0.35"},{"v":5.01514024412374,"d":"5.02"},{"v":2.32629004513911,"d":"2.33"},{"v":3.03977995869962E-3,"d":"0.00"},{"v":0.147882228740507,"d":"0.15"},"up","yes"]
["MSTRG.15405","IL13RA1","ENST00000371666;ENST00000371642;ENST00000481868","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005515(protein binding);GO:0004896(cytokine receptor activity);GO:0019221(cytokine-mediated signaling pathway);GO:0005886(plasma membrane);GO:0007166(cell surface receptor signaling pathway);GO:0005898(interleukin-13 receptor complex);GO:0005898(interleukin-13 receptor complex)","04630(Jak-STAT signaling pathway);04060(Cytokine-cytokine receptor interaction);05200(Pathways in cancer);05200(Pathways in cancer)","K05076","NA","interleukin 13 receptor subunit alpha 1 [Source:HGNC Symbol;Acc:HGNC:5974]",{"v":34.2197395855444,"d":"34.22"},{"v":7.04297101166514,"d":"7.04"},{"v":4.85870799821083,"d":"4.86"},{"v":2.28057273103684,"d":"2.28"},{"v":0.00304347306199785,"d":"0.00"},{"v":0.147882228740507,"d":"0.15"},"up","yes"]
["MSTRG.3892","SAP18","ENST00000621421;ENST00000382533;ENST00000607003;ENST00000467636;ENST00000471009;ENST00000450573;ENST00000485646;ENST00000492245","GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0016604(nuclear body);GO:0003723(RNA binding);GO:0006397(mRNA processing);GO:0008380(RNA splicing);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016607(nuclear speck);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0016575(histone deacetylation);GO:0005515(protein binding);GO:1903507(negative regulation of nucleic acid-templated transcription);GO:0043065(positive regulation of apoptotic process);GO:0003714(transcription corepressor activity);GO:0035145(exon-exon junction complex);GO:0004407(histone deacetylase activity);GO:0000381(regulation of alternative mRNA splicing, via spliceosome);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0048025(negative regulation of mRNA splicing, via spliceosome);GO:0000118(histone deacetylase complex);GO:0061574(ASAP complex);GO:0061574(ASAP complex)","03013(RNA transport);03015(mRNA surveillance pathway);03015(mRNA surveillance pathway)","K14324","NA","Sin3A associated protein 18 [Source:HGNC Symbol;Acc:HGNC:10530]",{"v":4.71415622290931,"d":"4.71"},{"v":15.8350022653121,"d":"15.84"},{"v":0.297704802558574,"d":"0.30"},{"v":-1.74804559964144,"d":"-1.75"},{"v":0.00306113598211777,"d":"0.00"},{"v":0.148120717334724,"d":"0.15"},"down","yes"]
["ENSG00000179588","ZFPM1","ENST00000319555;ENST00000563351;ENST00000562417","GO:0045599(negative regulation of fat cell differentiation);GO:0060412(ventricular septum morphogenesis);GO:0003151(outflow tract morphogenesis);GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0005654(nucleoplasm);GO:0005667(transcription factor complex);GO:0001085(RNA polymerase II transcription factor binding);GO:0001078(transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0032091(negative regulation of protein binding);GO:0045652(regulation of megakaryocyte differentiation);GO:0055008(cardiac muscle tissue morphogenesis);GO:0007596(blood coagulation);GO:0017053(transcriptional repressor complex);GO:0008134(transcription factor binding);GO:0030218(erythrocyte differentiation);GO:0010724(regulation of definitive erythrocyte differentiation);GO:0030219(megakaryocyte differentiation);GO:0030220(platelet formation);GO:0071733(transcriptional activation by promoter-enhancer looping);GO:0003181(atrioventricular valve morphogenesis);GO:0035162(embryonic hemopoiesis);GO:0060413(atrial septum morphogenesis);GO:0003192(mitral valve formation);GO:0000979(RNA polymerase II core promoter sequence-specific DNA binding);GO:0001102(RNA polymerase II activating transcription factor binding);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0002295(T-helper cell lineage commitment);GO:0003195(tricuspid valve formation);GO:0007507(heart development);GO:0030851(granulocyte differentiation);GO:0032642(regulation of chemokine production);GO:0035855(megakaryocyte development);GO:0045078(positive regulation of interferon-gamma biosynthetic process);GO:0045403(negative regulation of interleukin-4 biosynthetic process);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0048872(homeostasis of number of cells);GO:0060318(definitive erythrocyte differentiation);GO:0060319(primitive erythrocyte differentiation);GO:0060377(negative regulation of mast cell differentiation);GO:0005737(cytoplasm);GO:0005737(cytoplasm)","NA","NA","NA","zinc finger protein, FOG family member 1 [Source:HGNC Symbol;Acc:HGNC:19762]",{"v":1.05317170458265,"d":"1.05"},{"v":0.208920985270049,"d":"0.21"},{"v":5.04100487187217,"d":"5.04"},{"v":2.33371134863857,"d":"2.33"},{"v":3.08488569125149E-3,"d":"0.00"},{"v":0.148650529180513,"d":"0.15"},"up","yes"]
["ENSG00000103404","USP31","ENST00000219689;ENST00000567975","GO:0016579(protein deubiquitination);GO:0006511(ubiquitin-dependent protein catabolic process);GO:0036459(thiol-dependent ubiquitinyl hydrolase activity);GO:0016787(hydrolase activity);GO:0008233(peptidase activity);GO:0008234(cysteine-type peptidase activity);GO:0006508(proteolysis);GO:0004843(thiol-dependent ubiquitin-specific protease activity);GO:0005634(nucleus);GO:0005634(nucleus)","NA","NA","NA","ubiquitin specific peptidase 31 [Source:HGNC Symbol;Acc:HGNC:20060]",{"v":0.548270998418907,"d":"0.55"},{"v":0.109085818091038,"d":"0.11"},{"v":5.02605203878423,"d":"5.03"},{"v":2.3294256086852,"d":"2.33"},{"v":0.00312941564205301,"d":"0.00"},{"v":0.150173156409759,"d":"0.15"},"up","yes"]
["MSTRG.2904","BCL9L","MSTRG.2904.1;ENST00000334801;ENST00000527266;ENST00000532899;ENST00000530293;ENST00000526143","GO:0010718(positive regulation of epithelial to mesenchymal transition);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0030512(negative regulation of transforming growth factor beta receptor signaling pathway);GO:0005634(nucleus);GO:0005730(nucleolus);GO:0005654(nucleoplasm);GO:0003713(transcription coactivator activity);GO:0008013(beta-catenin binding);GO:0060070(canonical Wnt signaling pathway);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:1904837(beta-catenin-TCF complex assembly);GO:0022604(regulation of cell morphogenesis);GO:0035019(somatic stem cell population maintenance);GO:0035914(skeletal muscle cell differentiation);GO:1903506(regulation of nucleic acid-templated transcription);GO:1903506(regulation of nucleic acid-templated transcription)","NA","NA","NA","B-cell CLL/lymphoma 9 like [Source:HGNC Symbol;Acc:HGNC:23688]",{"v":9.24198014082626,"d":"9.24"},{"v":1.91339880211812,"d":"1.91"},{"v":4.83013793600971,"d":"4.83"},{"v":2.27206438921751,"d":"2.27"},{"v":0.00319053959028224,"d":"0.00"},{"v":0.152422463777234,"d":"0.15"},"up","yes"]
["MSTRG.2546","MALAT1","ENST00000534336;ENST00000620465;ENST00000508832;ENST00000620902;ENST00000612781;ENST00000618925;ENST00000610481;ENST00000618132;ENST00000544868;ENST00000613376;ENST00000617791","NA","NA","NA","NA","metastasis associated lung adenocarcinoma transcript 1 (non-protein coding) [Source:HGNC Symbol;Acc:HGNC:29665]",{"v":20.7411623653912,"d":"20.74"},{"v":4.3044272625928,"d":"4.30"},{"v":4.81856495651355,"d":"4.82"},{"v":2.26860355343055,"d":"2.27"},{"v":0.00320253863443082,"d":"0.00"},{"v":0.152422463777234,"d":"0.15"},"up","yes"]
["MSTRG.14893","TMEM245","ENST00000374586;ENST00000472207;ENST00000491854;ENST00000482868;ENST00000413712","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0003674(molecular_function);GO:0008150(biological_process);GO:0008150(biological_process)","NA","NA","NA","transmembrane protein 245 [Source:HGNC Symbol;Acc:HGNC:1363]",{"v":4.22994422068747,"d":"4.23"},{"v":0.872978136756643,"d":"0.87"},{"v":4.84541827863283,"d":"4.85"},{"v":2.27662121104022,"d":"2.28"},{"v":0.00323395985242789,"d":"0.00"},{"v":0.153289697005082,"d":"0.15"},"up","yes"]
["MSTRG.12351","FAM53C","ENST00000239906;ENST00000434981;ENST00000513056;ENST00000512180;ENST00000505136;ENST00000511024","GO:0005515(protein binding);GO:0005515(protein binding)","NA","NA","NA","family with sequence similarity 53 member C [Source:HGNC Symbol;Acc:HGNC:1336]",{"v":14.5554463165508,"d":"14.56"},{"v":3.02568973549851,"d":"3.03"},{"v":4.81062091257439,"d":"4.81"},{"v":2.26622311638185,"d":"2.27"},{"v":0.00326166397477386,"d":"0.00"},{"v":0.153397347882681,"d":"0.15"},"up","yes"]
["MSTRG.14915","SLC31A1","ENST00000374212;ENST00000496650","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0006811(ion transport);GO:0005886(plasma membrane);GO:0005375(copper ion transmembrane transporter activity);GO:0015088(copper uptake transmembrane transporter activity);GO:0006855(drug transmembrane transport);GO:0006878(cellular copper ion homeostasis);GO:0015677(copper ion import);GO:0035434(copper ion transmembrane transport);GO:0072719(cellular response to cisplatin);GO:0098705(copper ion import across plasma membrane);GO:0005737(cytoplasm);GO:0005770(late endosome);GO:0043025(neuronal cell body);GO:0055037(recycling endosome);GO:0005887(integral component of plasma membrane);GO:0006825(copper ion transport);GO:0006825(copper ion transport)","04978(Mineral absorption);01524(Platinum drug resistance);01524(Platinum drug resistance)","K14686","NA","solute carrier family 31 member 1 [Source:HGNC Symbol;Acc:HGNC:11016]",{"v":1.13930082835966,"d":"1.14"},{"v":3.80944008230934,"d":"3.81"},{"v":0.299073040589471,"d":"0.30"},{"v":-1.74143022776292,"d":"-1.74"},{"v":0.00326264917997264,"d":"0.00"},{"v":0.153397347882681,"d":"0.15"},"down","yes"]
["ENSG00000132846","ZBED3","ENST00000255198;ENST00000505685","GO:0003676(nucleic acid binding);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0046872(metal ion binding);GO:0003677(DNA binding);GO:0005829(cytosol);GO:0016055(Wnt signaling pathway);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0050821(protein stabilization);GO:0001933(negative regulation of protein phosphorylation);GO:0090263(positive regulation of canonical Wnt signaling pathway);GO:1903955(positive regulation of protein targeting to mitochondrion);GO:1903955(positive regulation of protein targeting to mitochondrion)","NA","NA","NA","zinc finger BED-type containing 3 [Source:HGNC Symbol;Acc:HGNC:20711]",{"v":0.866047005219527,"d":"0.87"},{"v":0.171594675468222,"d":"0.17"},{"v":5.0470505734306,"d":"5.05"},{"v":2.33544054308016,"d":"2.34"},{"v":0.0032758583679795,"d":"0.00"},{"v":0.153397351723169,"d":"0.15"},"up","yes"]
["MSTRG.14100","TRBV20-1","ENST00000390394","NA","NA","NA","NA","T-cell receptor beta variable 20-1 [Source:HGNC Symbol;Acc:HGNC:12196]",{"v":16.120863,"d":"16.12"},{"v":3.218576,"d":"3.22"},{"v":5.00869421756702,"d":"5.01"},{"v":2.32443453727647,"d":"2.32"},{"v":0.00330345044664502,"d":"0.00"},{"v":0.153620929730876,"d":"0.15"},"up","yes"]
["MSTRG.9820",null,"MSTRG.9820.1","NA","NA","NA","NA",null,{"v":2.813912,"d":"2.81"},{"v":0.561622,"d":"0.56"},{"v":5.01033079188493,"d":"5.01"},{"v":2.32490585612662,"d":"2.32"},{"v":0.00330708967818126,"d":"0.00"},{"v":0.153620929730876,"d":"0.15"},"up","yes"]
["MSTRG.9248","WIPF1","ENST00000392547;ENST00000272746;ENST00000409415;ENST00000470752;ENST00000409891;ENST00000487291;MSTRG.9248.4;MSTRG.9248.5;ENST00000436221;ENST00000455428;ENST00000467149;ENST00000410117;ENST00000392546;ENST00000488830;ENST00000359761;ENST00000480400;ENST00000469002;MSTRG.9248.1;ENST00000490887;ENST00000474332;MSTRG.9248.3","GO:0005737(cytoplasm);GO:0003779(actin binding);GO:0015629(actin cytoskeleton);GO:0008154(actin polymerization or depolymerization);GO:0005856(cytoskeleton);GO:0042995(cell projection);GO:0005515(protein binding);GO:0031410(cytoplasmic vesicle);GO:0038096(Fc-gamma receptor signaling pathway involved in phagocytosis);GO:0030048(actin filament-based movement);GO:0051707(response to other organism);GO:0005884(actin filament);GO:0005829(cytosol);GO:0017124(SH3 domain binding);GO:0001726(ruffle);GO:0006461(protein complex assembly);GO:0005522(profilin binding);GO:0005522(profilin binding)","04144(Endocytosis);04144(Endocytosis)","K19475","NA","WAS/WASL interacting protein family member 1 [Source:HGNC Symbol;Acc:HGNC:12736]",{"v":35.8897338169935,"d":"35.89"},{"v":7.49000777748512,"d":"7.49"},{"v":4.79168178234442,"d":"4.79"},{"v":2.26053210130752,"d":"2.26"},{"v":0.00332173853132148,"d":"0.00"},{"v":0.153686651650344,"d":"0.15"},"up","yes"]
["ENSG00000171634","BPTF","ENST00000321892;ENST00000306378;ENST00000581258;ENST00000424123;ENST00000342579;ENST00000577837;ENST00000467104;ENST00000544778;ENST00000582467;ENST00000582406;ENST00000579173;ENST00000580465;ENST00000584931;ENST00000544491;ENST00000577770;ENST00000578307","GO:0046872(metal ion binding);GO:0005654(nucleoplasm);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0016569(covalent chromatin modification);GO:0005515(protein binding);GO:0070062(extracellular exosome);GO:0000790(nuclear chromatin);GO:0045893(positive regulation of transcription, DNA-templated);GO:0048188(Set1C/COMPASS complex);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0016589(NURF complex);GO:0008134(transcription factor binding);GO:0043565(sequence-specific DNA binding);GO:0007420(brain development);GO:0008094(DNA-dependent ATPase activity);GO:0006338(chromatin remodeling);GO:0001892(embryonic placenta development);GO:0007492(endoderm development);GO:0009611(response to wounding);GO:0009952(anterior/posterior pattern specification);GO:1990090(cellular response to nerve growth factor stimulus);GO:0030425(dendrite);GO:0043005(neuron projection);GO:0044297(cell body);GO:0048471(perinuclear region of cytoplasm);GO:0048471(perinuclear region of cytoplasm)","NA","NA","NA","bromodomain PHD finger transcription factor [Source:HGNC Symbol;Acc:HGNC:3581]",{"v":6.36777190011922,"d":"6.37"},{"v":1.32616136759836,"d":"1.33"},{"v":4.8016569142344,"d":"4.80"},{"v":2.26353232447309,"d":"2.26"},{"v":3.33647482160245E-3,"d":"0.00"},{"v":0.15375588136218,"d":"0.15"},"up","yes"]
["MSTRG.14000","CREB3L2","ENST00000330387;ENST00000420629;ENST00000456390;ENST00000458726;ENST00000452463","GO:0005634(nucleus);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005783(endoplasmic reticulum);GO:0005654(nucleoplasm);GO:0006355(regulation of transcription, DNA-templated);GO:0006366(transcription from RNA polymerase II promoter);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0005789(endoplasmic reticulum membrane);GO:0007275(multicellular organism development);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0045893(positive regulation of transcription, DNA-templated);GO:0035497(cAMP response element binding);GO:0030968(endoplasmic reticulum unfolded protein response);GO:0006986(response to unfolded protein);GO:0051216(cartilage development);GO:0044212(transcription regulatory region DNA binding);GO:0034976(response to endoplasmic reticulum stress);GO:0002062(chondrocyte differentiation);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:0001077(transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0006888(ER to Golgi vesicle-mediated transport);GO:0006888(ER to Golgi vesicle-mediated transport)","04668(TNF signaling pathway);04024(cAMP signaling pathway);04022(cGMP - PKG signaling pathway);04151(PI3K-Akt signaling pathway);04152(AMPK signaling pathway);04911(Insulin secretion);04922(Glucagon signaling pathway);04915(Estrogen signaling pathway);04926(Relaxin signaling pathway);04918(Thyroid hormone synthesis);04916(Melanogenesis);04925(Aldosterone synthesis and secretion);04927(Cortisol synthesis and secretion);04261(Adrenergic signaling in cardiomyocytes);04962(Vasopressin-regulated water reabsorption);04725(Cholinergic synapse);04728(Dopaminergic synapse);04211(Longevity regulating pathway - mammal);05203(Viral carcinogenesis);05215(Prostate cancer);05016(Huntington's disease);05030(Cocaine addiction);05031(Amphetamine addiction);05034(Alcoholism);04931(Insulin resistance);05161(Hepatitis B);05165(Human papillomavirus infection);05165(Human papillomavirus infection)","K09048","NA","cAMP responsive element binding protein 3 like 2 [Source:HGNC Symbol;Acc:HGNC:23720]",{"v":4.32055155234411,"d":"4.32"},{"v":0.897568176490669,"d":"0.90"},{"v":4.81361936119069,"d":"4.81"},{"v":2.26712206465538,"d":"2.27"},{"v":0.00337937917751778,"d":"0.00"},{"v":0.155117511417051,"d":"0.16"},"up","yes"]
["ENSG00000133678","TMEM254","ENST00000463209;ENST00000372274;ENST00000372275;ENST00000372281;ENST00000372273;ENST00000472622;ENST00000483732","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016021(integral component of membrane)","NA","NA","NA","transmembrane protein 254 [Source:HGNC Symbol;Acc:HGNC:25804]",{"v":0.278873344459279,"d":"0.28"},{"v":0.999204642189586,"d":"1.00"},{"v":0.279095325105952,"d":"0.28"},{"v":-1.84117013566771,"d":"-1.84"},{"v":0.00341347663979775,"d":"0.00"},{"v":0.15558512208971,"d":"0.16"},"down","yes"]
["MSTRG.3750","MED13L","ENST00000281928;ENST00000552340;ENST00000549786;ENST00000549755;ENST00000548784;ENST00000548694;ENST00000552447","GO:0005634(nucleus);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0001104(RNA polymerase II transcription cofactor activity);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0016592(mediator complex);GO:0016592(mediator complex)","04919(Thyroid hormone signaling pathway);04919(Thyroid hormone signaling pathway)","K15164","NA","mediator complex subunit 13 like [Source:HGNC Symbol;Acc:HGNC:22962]",{"v":11.6539591047426,"d":"11.65"},{"v":2.4432803026605,"d":"2.44"},{"v":4.769800293504,"d":"4.77"},{"v":2.25392886337903,"d":"2.25"},{"v":0.00341636150287404,"d":"0.00"},{"v":0.15558512208971,"d":"0.16"},"up","yes"]
["ENSG00000130338","TULP4","ENST00000367097;ENST00000432358;ENST00000620026;ENST00000367094","GO:0005737(cytoplasm);GO:0016567(protein ubiquitination);GO:0035556(intracellular signal transduction);GO:0005829(cytosol);GO:0043687(post-translational protein modification);GO:0005929(cilium);GO:0035091(phosphatidylinositol binding);GO:0061512(protein localization to cilium);GO:0005622(intracellular);GO:0005622(intracellular)","NA","NA","NA","tubby like protein 4 [Source:HGNC Symbol;Acc:HGNC:15530]",{"v":1.38203716271876,"d":"1.38"},{"v":0.286249695482296,"d":"0.29"},{"v":4.8280825605428,"d":"4.83"},{"v":2.27145034648798,"d":"2.27"},{"v":0.00346309313852771,"d":"0.00"},{"v":0.157097268037978,"d":"0.16"},"up","yes"]
["MSTRG.7631","DOT1L","ENST00000398665;ENST00000608122;ENST00000482433;ENST00000478937;ENST00000452696;ENST00000457590","GO:0005634(nucleus);GO:0043231(intracellular membrane-bounded organelle);GO:0005654(nucleoplasm);GO:0008168(methyltransferase activity);GO:0016740(transferase activity);GO:0032259(methylation);GO:0016569(covalent chromatin modification);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0018024(histone-lysine N-methyltransferase activity);GO:0051726(regulation of cell cycle);GO:0031151(histone methyltransferase activity (H3-K79 specific));GO:0034729(histone H3-K79 methylation);GO:0043234(protein complex);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0006281(DNA repair);GO:0042054(histone methyltransferase activity);GO:0008284(positive regulation of cell proliferation);GO:0032200(telomere organization);GO:0000077(DNA damage checkpoint);GO:0000781(chromosome, telomeric region);GO:0006342(chromatin silencing);GO:0006348(chromatin silencing at telomere);GO:0046425(regulation of JAK-STAT cascade);GO:2000677(regulation of transcription regulatory region DNA binding);GO:2000677(regulation of transcription regulatory region DNA binding)","00310(Lysine degradation);05202(Transcriptional misregulation in cancers);05202(Transcriptional misregulation in cancers)","K11427","EC:2.1.1.43","DOT1 like histone lysine methyltransferase [Source:HGNC Symbol;Acc:HGNC:24948]",{"v":1.71257376978353,"d":"1.71"},{"v":0.353219413413769,"d":"0.35"},{"v":4.84847011445938,"d":"4.85"},{"v":2.27752959132674,"d":"2.28"},{"v":3.48922390621956E-3,"d":"0.00"},{"v":0.157118353298644,"d":"0.16"},"up","yes"]
["MSTRG.449","MACF1","ENST00000564288;ENST00000497964;ENST00000485063;ENST00000446276;ENST00000472385;ENST00000462496;ENST00000480624;ENST00000497807;ENST00000442046;ENST00000469490;ENST00000289893;ENST00000462103;ENST00000372925;ENST00000487656;ENST00000567887;ENST00000528611;ENST00000496360;ENST00000469366;ENST00000484793;MSTRG.449.17;ENST00000530275;ENST00000602421;ENST00000484393;ENST00000361689;ENST00000467673;ENST00000530262","GO:0003779(actin binding);GO:0005509(calcium ion binding);GO:0005856(cytoskeleton);GO:0008017(microtubule binding);GO:0016055(Wnt signaling pathway);GO:0016887(ATPase activity);GO:0003723(RNA binding);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0046872(metal ion binding);GO:0005794(Golgi apparatus);GO:0005886(plasma membrane);GO:0042995(cell projection);GO:0005515(protein binding);GO:0005874(microtubule);GO:0045296(cadherin binding);GO:0051015(actin filament binding);GO:0045773(positive regulation of axon extension);GO:0032587(ruffle membrane);GO:0042060(wound healing);GO:0051893(regulation of focal adhesion assembly);GO:0032886(regulation of microtubule-based process);GO:0030177(positive regulation of Wnt signaling pathway);GO:0010632(regulation of epithelial cell migration);GO:0043001(Golgi to plasma membrane protein transport);GO:0016021(integral component of membrane);GO:0030054(cell junction);GO:0015629(actin cytoskeleton);GO:0015629(actin cytoskeleton)","NA","NA","NA","microtubule-actin crosslinking factor 1 [Source:HGNC Symbol;Acc:HGNC:13664]",{"v":4.93575797440945,"d":"4.94"},{"v":1.03786338467848,"d":"1.04"},{"v":4.75569140146369,"d":"4.76"},{"v":2.24965510111749,"d":"2.25"},{"v":3.49061699397659E-3,"d":"0.00"},{"v":0.157118353298644,"d":"0.16"},"up","yes"]
["MSTRG.8130","SAMD4B","ENST00000611159;ENST00000602243;ENST00000595476;ENST00000314471;ENST00000598605;ENST00000599712;ENST00000596271;ENST00000601613;ENST00000598913;ENST00000594204","GO:0003723(RNA binding);GO:0005829(cytosol);GO:0006355(regulation of transcription, DNA-templated);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0006351(transcription, DNA-templated);GO:0003729(mRNA binding);GO:0000932(P-body);GO:0017148(negative regulation of translation);GO:0000289(nuclear-transcribed mRNA poly(A) tail shortening);GO:0030371(translation repressor activity);GO:0043488(regulation of mRNA stability);GO:0043488(regulation of mRNA stability)","NA","NA","NA","sterile alpha motif domain containing 4B [Source:HGNC Symbol;Acc:HGNC:25492]",{"v":3.1669946492491,"d":"3.17"},{"v":0.657459153034628,"d":"0.66"},{"v":4.81702115581057,"d":"4.82"},{"v":2.26814126009179,"d":"2.27"},{"v":0.00353928070904946,"d":"0.00"},{"v":0.158693694494948,"d":"0.16"},"up","yes"]
["ENSG00000173064","HECTD4","ENST00000377560;ENST00000548896;ENST00000549306;ENST00000550968;ENST00000550722;ENST00000547085;ENST00000548588;ENST00000549141;ENST00000552437;ENST00000311694;ENST00000547352;ENST00000547519;ENST00000548140","GO:0016740(transferase activity);GO:0016567(protein ubiquitination);GO:0004842(ubiquitin-protein transferase activity);GO:0004842(ubiquitin-protein transferase activity)","NA","NA","NA","HECT domain E3 ubiquitin protein ligase 4 [Source:HGNC Symbol;Acc:HGNC:26611]",{"v":2.3519486219173,"d":"2.35"},{"v":0.492373766920082,"d":"0.49"},{"v":4.77675453066745,"d":"4.78"},{"v":2.25603074105706,"d":"2.26"},{"v":0.00355518891343352,"d":"0.00"},{"v":0.158793880198859,"d":"0.16"},"up","yes"]
["MSTRG.2939","SORL1","ENST00000528339;ENST00000260197;ENST00000534754;ENST00000524633;ENST00000530365;ENST00000532694;ENST00000527934;ENST00000529445;MSTRG.2939.1;ENST00000524873;ENST00000532451;ENST00000527649;ENST00000525532","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005794(Golgi apparatus);GO:0006629(lipid metabolic process);GO:0008202(steroid metabolic process);GO:0005576(extracellular region);GO:0005615(extracellular space);GO:0006869(lipid transport);GO:0008203(cholesterol metabolic process);GO:0007165(signal transduction);GO:0005515(protein binding);GO:0005768(endosome);GO:0006897(endocytosis);GO:0070062(extracellular exosome);GO:0044267(cellular protein metabolic process);GO:0010008(endosome membrane);GO:0005887(integral component of plasma membrane);GO:0006605(protein targeting);GO:0000139(Golgi membrane);GO:0004888(transmembrane signaling receptor activity);GO:0006898(receptor-mediated endocytosis);GO:0005041(low-density lipoprotein receptor activity);GO:0030169(low-density lipoprotein particle binding);GO:0034362(low-density lipoprotein particle);GO:1901215(negative regulation of neuron death);GO:1902430(negative regulation of amyloid-beta formation);GO:0005641(nuclear envelope lumen);GO:0001540(amyloid-beta binding);GO:1902963(negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process);GO:0030306(ADP-ribosylation factor binding);GO:0000042(protein targeting to Golgi);GO:0006622(protein targeting to lysosome);GO:0006892(post-Golgi vesicle-mediated transport);GO:0014910(regulation of smooth muscle cell migration);GO:0032091(negative regulation of protein binding);GO:0032460(negative regulation of protein oligomerization);GO:0043407(negative regulation of MAP kinase activity);GO:0045053(protein retention in Golgi apparatus);GO:0045732(positive regulation of protein catabolic process);GO:0050768(negative regulation of neurogenesis);GO:0051604(protein maturation);GO:0070863(positive regulation of protein exit from endoplasmic reticulum);GO:1902771(positive regulation of choline O-acetyltransferase activity);GO:1902948(negative regulation of tau-protein kinase activity);GO:1902953(positive regulation of ER to Golgi vesicle-mediated transport);GO:1902955(positive regulation of early endosome to recycling endosome transport);GO:1902960(negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process);GO:1902966(positive regulation of protein localization to early endosome);GO:1902997(negative regulation of neurofibrillary tangle assembly);GO:2001137(positive regulation of endocytic recycling);GO:0005769(early endosome);GO:0005783(endoplasmic reticulum);GO:0005802(trans-Golgi network);GO:0031985(Golgi cisterna);GO:0055037(recycling endosome);GO:0055037(recycling endosome)","NA","NA","NA","sortilin related receptor 1 [Source:HGNC Symbol;Acc:HGNC:11185]",{"v":68.9762076814005,"d":"68.98"},{"v":14.5797929948057,"d":"14.58"},{"v":4.7309456112288,"d":"4.73"},{"v":2.24212857516758,"d":"2.24"},{"v":0.00357174714890486,"d":"0.00"},{"v":0.1588739543325,"d":"0.16"},"up","yes"]
["MSTRG.13731","POM121C","MSTRG.13731.4;ENST00000614583;ENST00000439629;MSTRG.13731.3;ENST00000615331;ENST00000607367;MSTRG.13731.6;ENST00000398379;ENST00000479864;ENST00000473609","GO:0005654(nucleoplasm);GO:0031965(nuclear membrane);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016021(integral component of membrane)","03013(RNA transport);03013(RNA transport)","K14316","NA","POM121 transmembrane nucleoporin C [Source:HGNC Symbol;Acc:HGNC:34005]",{"v":5.19966586604775,"d":"5.20"},{"v":1.09035216434571,"d":"1.09"},{"v":4.76879492339792,"d":"4.77"},{"v":2.2536247426068,"d":"2.25"},{"v":0.00358480031749551,"d":"0.00"},{"v":0.1588739543325,"d":"0.16"},"up","yes"]
["MSTRG.5953","PLLP","ENST00000219207;ENST00000613167;ENST00000564376","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0006810(transport);GO:0006811(ion transport);GO:0005515(protein binding);GO:0009611(response to wounding);GO:0042552(myelination);GO:0043218(compact myelin);GO:0045121(membrane raft);GO:0070062(extracellular exosome);GO:0008104(protein localization);GO:0019911(structural constituent of myelin sheath);GO:0001766(membrane raft polarization);GO:0001766(membrane raft polarization)","NA","NA","NA","plasmolipin [Source:HGNC Symbol;Acc:HGNC:18553]",{"v":0.482047526834862,"d":"0.48"},{"v":0.0963451389908257,"d":"0.10"},{"v":5.00334040600392,"d":"5.00"},{"v":2.32289161050514,"d":"2.32"},{"v":0.00359802376555994,"d":"0.00"},{"v":0.1588739543325,"d":"0.16"},"up","yes"]
["ENSG00000103489","XYLT1","ENST00000261381;ENST00000575674;ENST00000568226;ENST00000563403","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016740(transferase activity);GO:0016757(transferase activity, transferring glycosyl groups);GO:0005794(Golgi apparatus);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005576(extracellular region);GO:0000139(Golgi membrane);GO:0008375(acetylglucosaminyltransferase activity);GO:0030158(protein xylosyltransferase activity);GO:0006024(glycosaminoglycan biosynthetic process);GO:0030203(glycosaminoglycan metabolic process);GO:0015012(heparan sulfate proteoglycan biosynthetic process);GO:0030206(chondroitin sulfate biosynthetic process);GO:0030206(chondroitin sulfate biosynthetic process)","00532(Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate);00534(Glycosaminoglycan biosynthesis - heparan sulfate / heparin);00534(Glycosaminoglycan biosynthesis - heparan sulfate / heparin)","K00771","EC:2.4.2.26","xylosyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:15516]",{"v":3.27232782415485,"d":"3.27"},{"v":0.689729885223555,"d":"0.69"},{"v":4.74436137140009,"d":"4.74"},{"v":2.24621390214174,"d":"2.25"},{"v":0.00366107118019945,"d":"0.00"},{"v":0.160148624596177,"d":"0.16"},"up","yes"]
["ENSG00000243660","ZNF487","ENST00000315429;ENST00000437590;ENST00000596267;ENST00000456416;ENST00000490208","GO:0003676(nucleic acid binding);GO:0006355(regulation of transcription, DNA-templated);GO:0005622(intracellular);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0003677(DNA binding)","NA","NA","NA","zinc finger protein 487 [Source:HGNC Symbol;Acc:HGNC:23488]",{"v":0.234357349477492,"d":"0.23"},{"v":0.819202103697749,"d":"0.82"},{"v":0.286080014223157,"d":"0.29"},{"v":-1.80550938152643,"d":"-1.81"},{"v":3.6626048231876E-3,"d":"0.00"},{"v":0.160148624596177,"d":"0.16"},"down","yes"]
["MSTRG.15318","HUWE1","ENST00000342160;ENST00000426907;ENST00000446750;ENST00000463852;ENST00000474971;ENST00000471676;ENST00000474288;ENST00000612484;ENST00000480438;ENST00000488459;ENST00000262854;ENST00000622887","GO:0016740(transferase activity);GO:0016567(protein ubiquitination);GO:0004842(ubiquitin-protein transferase activity);GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0006281(DNA repair);GO:0006974(cellular response to DNA damage stimulus);GO:0030154(cell differentiation);GO:0005576(extracellular region);GO:0061630(ubiquitin protein ligase activity);GO:0070062(extracellular exosome);GO:0000209(protein polyubiquitination);GO:0042787(protein ubiquitination involved in ubiquitin-dependent protein catabolic process);GO:0043312(neutrophil degranulation);GO:0006284(base-excision repair);GO:0034774(secretory granule lumen);GO:1904813(ficolin-1-rich granule lumen);GO:1903955(positive regulation of protein targeting to mitochondrion);GO:0006513(protein monoubiquitination);GO:0016574(histone ubiquitination);GO:0016574(histone ubiquitination)","04120(Ubiquitin mediated proteolysis);04120(Ubiquitin mediated proteolysis)","K10592","EC:2.3.2.26","HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase [Source:HGNC Symbol;Acc:HGNC:30892]",{"v":9.87710125719217,"d":"9.88"},{"v":2.09276253210587,"d":"2.09"},{"v":4.71964740655654,"d":"4.72"},{"v":2.23867908335551,"d":"2.24"},{"v":0.00367921287385011,"d":"0.00"},{"v":0.160148624596177,"d":"0.16"},"up","yes"]
["ENSG00000214425","LRRC37A4P","ENST00000581296;ENST00000579913","NA","NA","NA","NA","leucine rich repeat containing 37 member A4, pseudogene [Source:HGNC Symbol;Acc:HGNC:25479]",{"v":1.87896419425188,"d":"1.88"},{"v":0.390880271952629,"d":"0.39"},{"v":4.8070069764984,"d":"4.81"},{"v":2.26513889728741,"d":"2.27"},{"v":0.00368205311006451,"d":"0.00"},{"v":0.160148624596177,"d":"0.16"},"up","yes"]
["MSTRG.15344","SNX12","ENST00000374274;ENST00000465030;ENST00000622277;ENST00000276105;ENST00000622259","GO:0006810(transport);GO:0016020(membrane);GO:0015031(protein transport);GO:0005515(protein binding);GO:0035091(phosphatidylinositol binding);GO:0008289(lipid binding);GO:0070062(extracellular exosome);GO:0005769(early endosome);GO:0019898(extrinsic component of membrane);GO:0019899(enzyme binding);GO:0010629(negative regulation of gene expression);GO:0051224(negative regulation of protein transport);GO:0042177(negative regulation of protein catabolic process);GO:2000642(negative regulation of early endosome to late endosome transport);GO:0016050(vesicle organization);GO:0030100(regulation of endocytosis);GO:0010955(negative regulation of protein processing);GO:0010955(negative regulation of protein processing)","04144(Endocytosis);04144(Endocytosis)","K17918","NA","sorting nexin 12 [Source:HGNC Symbol;Acc:HGNC:14976]",{"v":2.11460625973025,"d":"2.11"},{"v":6.97139875722543,"d":"6.97"},{"v":0.303325965616095,"d":"0.30"},{"v":-1.72105909259899,"d":"-1.72"},{"v":0.0036966781549798,"d":"0.00"},{"v":0.16018478885739,"d":"0.16"},"down","yes"]
["ENSG00000089335","ZNF302","ENST00000423823;ENST00000509196;ENST00000457781;ENST00000505365;ENST00000613363;ENST00000512455;ENST00000502743;ENST00000510002;ENST00000505163;ENST00000505242;ENST00000446502;ENST00000509528","GO:0003676(nucleic acid binding);GO:0006355(regulation of transcription, DNA-templated);GO:0005622(intracellular);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding)","NA","NA","NA","zinc finger protein 302 [Source:HGNC Symbol;Acc:HGNC:13848]",{"v":0.967070045707472,"d":"0.97"},{"v":3.19824314328299,"d":"3.20"},{"v":0.302375398736813,"d":"0.30"},{"v":-1.7255873282258,"d":"-1.73"},{"v":0.0037322849978529,"d":"0.00"},{"v":0.160546778527545,"d":"0.16"},"down","yes"]
["MSTRG.14277","HMBOX1","ENST00000287701;ENST00000522468;ENST00000519662;ENST00000560599;ENST00000521516;ENST00000397358;ENST00000518080;ENST00000517386;ENST00000560357;ENST00000524238;ENST00000561377;ENST00000523613;ENST00000558662","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0045893(positive regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0016604(nuclear body);GO:0042802(identical protein binding);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0000784(nuclear chromosome, telomeric region);GO:0043565(sequence-specific DNA binding);GO:0045892(negative regulation of transcription, DNA-templated);GO:0032212(positive regulation of telomere maintenance via telomerase);GO:0051973(positive regulation of telomerase activity);GO:0003720(telomerase activity);GO:0005697(telomerase holoenzyme complex);GO:0001227(transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding);GO:0042162(telomeric DNA binding);GO:0003691(double-stranded telomeric DNA binding);GO:0032403(protein complex binding);GO:0006278(RNA-dependent DNA biosynthetic process);GO:0035563(positive regulation of chromatin binding);GO:0035563(positive regulation of chromatin binding)","NA","NA","NA","homeobox containing 1 [Source:HGNC Symbol;Acc:HGNC:26137]",{"v":1.70800622218872,"d":"1.71"},{"v":0.354473992463069,"d":"0.35"},{"v":4.81842464751958,"d":"4.82"},{"v":2.26856154382005,"d":"2.27"},{"v":0.00373268149508631,"d":"0.00"},{"v":0.160546778527545,"d":"0.16"},"up","yes"]
["ENSG00000105926","MPP6","ENST00000222644;ENST00000426450;ENST00000409761;ENST00000472674;ENST00000430180;ENST00000432190","GO:0016020(membrane);GO:0005515(protein binding);GO:0030165(PDZ domain binding);GO:0005886(plasma membrane);GO:0070062(extracellular exosome);GO:0006461(protein complex assembly);GO:0006461(protein complex assembly)","NA","NA","NA","membrane palmitoylated protein 6 [Source:HGNC Symbol;Acc:HGNC:18167]",{"v":0.494563150389583,"d":"0.49"},{"v":0.0967852894652578,"d":"0.10"},{"v":5.10989999742794,"d":"5.11"},{"v":2.3532950573808,"d":"2.35"},{"v":0.00376504976152425,"d":"0.00"},{"v":0.161341412843473,"d":"0.16"},"up","yes"]
["ENSG00000197008","ZNF138","ENST00000307355;ENST00000494380;ENST00000359735;ENST00000437743;ENST00000440598;ENST00000440155;ENST00000430838","GO:0003676(nucleic acid binding);GO:0046872(metal ion binding);GO:0006355(regulation of transcription, DNA-templated);GO:0005622(intracellular);GO:0005634(nucleus);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016021(integral component of membrane)","NA","NA","NA","zinc finger protein 138 [Source:HGNC Symbol;Acc:HGNC:12922]",{"v":0.324086656842105,"d":"0.32"},{"v":1.15002119789474,"d":"1.15"},{"v":0.281809289633432,"d":"0.28"},{"v":-1.82720892508798,"d":"-1.83"},{"v":0.00378724486012341,"d":"0.00"},{"v":0.161695862355195,"d":"0.16"},"down","yes"]
["MSTRG.10842","HIGD1A;AC099329.1;CCDC13;HHATL;AC099329.3","ENST00000321331;ENST00000449063;ENST00000479631;ENST00000310232;ENST00000629885;ENST00000418900;ENST00000470543;ENST00000490003;ENST00000430190;ENST00000480939;ENST00000625589;ENST00000431549;ENST00000452906;ENST00000441594","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005654(nucleoplasm);GO:0055114(oxidation-reduction process);GO:0005739(mitochondrion);GO:0005743(mitochondrial inner membrane);GO:0070469(respiratory chain);GO:0031966(mitochondrial membrane);GO:0061418(regulation of transcription from RNA polymerase II promoter in response to hypoxia);GO:0043066(negative regulation of apoptotic process);GO:0043234(protein complex);GO:0005737(cytoplasm);GO:0005634(nucleus);GO:0005829(cytosol);GO:0005813(centrosome);GO:0005856(cytoskeleton);GO:0042995(cell projection);GO:0005815(microtubule organizing center);GO:0030030(cell projection organization);GO:0005515(protein binding);GO:1905515(non-motile cilium assembly);GO:0031122(cytoplasmic microtubule organization);GO:0006974(cellular response to DNA damage stimulus);GO:0034451(centriolar satellite);GO:0060262(negative regulation of N-terminal protein palmitoylation);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0048471(perinuclear region of cytoplasm);GO:0048471(perinuclear region of cytoplasm)","NA","NA","NA","HIG1 hypoxia inducible domain family member 1A [Source:HGNC Symbol;Acc:HGNC:29527];coiled-coil domain containing 13 [Source:HGNC Symbol;Acc:HGNC:26358];hedgehog acyltransferase like [Source:HGNC Symbol;Acc:HGNC:13242]",{"v":1.18221757498749,"d":"1.18"},{"v":3.84910796768384,"d":"3.85"},{"v":0.307140663476602,"d":"0.31"},{"v":-1.70302856625175,"d":"-1.70"},{"v":3.8369154435943E-3,"d":"0.00"},{"v":0.162465928479413,"d":"0.16"},"down","yes"]
["MSTRG.13703","POM121B","ENST00000380760;MSTRG.13703.2","NA","NA","NA","NA","POM121 transmembrane nucleoporin B (pseudogene) [Source:HGNC Symbol;Acc:HGNC:34004]",{"v":3.3425110068328,"d":"3.34"},{"v":0.695428374598071,"d":"0.70"},{"v":4.80640584843067,"d":"4.81"},{"v":2.26495847343602,"d":"2.26"},{"v":0.00383979337886968,"d":"0.00"},{"v":0.162465928479413,"d":"0.16"},"up","yes"]
["MSTRG.10492","EP300","ENST00000263253;ENST00000635552;MSTRG.10492.4;ENST00000634690;ENST00000634422;ENST00000634728;ENST00000635584;ENST00000634787;ENST00000635083;ENST00000635538;MSTRG.10492.7","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0016740(transferase activity);GO:0003713(transcription coactivator activity);GO:0006355(regulation of transcription, DNA-templated);GO:0006366(transcription from RNA polymerase II promoter);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0016746(transferase activity, transferring acyl groups);GO:0005515(protein binding);GO:0000123(histone acetyltransferase complex);GO:0007049(cell cycle);GO:0007623(circadian rhythm);GO:0048511(rhythmic process);GO:0006915(apoptotic process);GO:0004402(histone acetyltransferase activity);GO:0003712(transcription cofactor activity);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0016573(histone acetylation);GO:0001047(core promoter binding);GO:0006977(DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0045444(fat cell differentiation);GO:0031648(protein destabilization);GO:0050821(protein stabilization);GO:0002223(stimulatory C-type lectin receptor signaling pathway);GO:0016579(protein deubiquitination);GO:0061418(regulation of transcription from RNA polymerase II promoter in response to hypoxia);GO:0003682(chromatin binding);GO:0001666(response to hypoxia);GO:0016032(viral process);GO:0007399(nervous system development);GO:0045815(positive regulation of gene expression, epigenetic);GO:0008134(transcription factor binding);GO:0043967(histone H4 acetylation);GO:1904837(beta-catenin-TCF complex assembly);GO:1901796(regulation of signal transduction by p53 class mediator);GO:0007219(Notch signaling pathway);GO:0051091(positive regulation of sequence-specific DNA binding transcription factor activity);GO:0001102(RNA polymerase II activating transcription factor binding);GO:0043627(response to estrogen);GO:0045652(regulation of megakaryocyte differentiation);GO:0032481(positive regulation of type I interferon production);GO:0008013(beta-catenin binding);GO:0042771(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator);GO:1900034(regulation of cellular response to heat);GO:0006283(transcription-coupled nucleotide-excision repair);GO:0003684(damaged DNA binding);GO:0035257(nuclear hormone receptor binding);GO:0050681(androgen receptor binding);GO:0008022(protein C-terminus binding);GO:0051726(regulation of cell cycle);GO:0034644(cellular response to UV);GO:0010506(regulation of autophagy);GO:0006990(positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response);GO:0060765(regulation of androgen receptor signaling pathway);GO:0006475(internal protein amino acid acetylation);GO:0010742(macrophage derived foam cell differentiation);GO:0016407(acetyltransferase activity);GO:0006473(protein acetylation);GO:0018393(internal peptidyl-lysine acetylation);GO:0043923(positive regulation by host of viral transcription);GO:0033613(activating transcription factor binding);GO:0000979(RNA polymerase II core promoter sequence-specific DNA binding);GO:0001085(RNA polymerase II transcription factor binding);GO:0001228(transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding);GO:0002039(p53 binding);GO:0004468(lysine N-acetyltransferase activity, acting on acetyl phosphate as donor);GO:0031490(chromatin DNA binding);GO:0034212(peptide N-acetyltransferase activity);GO:0061733(peptide-lysine-N-acetyltransferase activity);GO:0097157(pre-mRNA intronic binding);GO:0001756(somitogenesis);GO:0007507(heart development);GO:0007519(skeletal muscle tissue development);GO:0009887(animal organ morphogenesis);GO:0010628(positive regulation of gene expression);GO:0018076(N-terminal peptidyl-lysine acetylation);GO:0030183(B cell differentiation);GO:0030220(platelet formation);GO:0030324(lung development);GO:0032092(positive regulation of protein binding);GO:0035855(megakaryocyte development);GO:0043969(histone H2B acetylation);GO:0045893(positive regulation of transcription, DNA-templated);GO:0090043(regulation of tubulin deacetylation);GO:0005667(transcription factor complex);GO:0043234(protein complex);GO:0043234(protein complex)","04310(Wnt signaling pathway);04330(Notch signaling pathway);04350(TGF-beta signaling pathway);04630(Jak-STAT signaling pathway);04066(HIF-1 signaling pathway);04068(FoxO signaling pathway);04024(cAMP signaling pathway);04110(Cell cycle);04520(Adherens junction);04922(Glucagon signaling pathway);04919(Thyroid hormone signaling pathway);04916(Melanogenesis);04720(Long-term potentiation);05200(Pathways in cancer);05206(MicroRNAs in cancer);05203(Viral carcinogenesis);05211(Renal cell carcinoma);05215(Prostate cancer);05016(Huntington's disease);05152(Tuberculosis);05166(HTLV-I infection);05164(Influenza A);05161(Hepatitis B);05168(Herpes simplex infection);05167(Kaposi's sarcoma-associated herpesvirus infection);05169(Epstein-Barr virus infection);05165(Human papillomavirus infection);05165(Human papillomavirus infection)","K04498","EC:2.3.1.48","E1A binding protein p300 [Source:HGNC Symbol;Acc:HGNC:3373]",{"v":9.64952271761036,"d":"9.65"},{"v":2.06112091010877,"d":"2.06"},{"v":4.68168687740941,"d":"4.68"},{"v":2.22702844672779,"d":"2.23"},{"v":3.86086939661304E-3,"d":"0.00"},{"v":0.162465928479413,"d":"0.16"},"up","yes"]
["ENSG00000204131","NHSL2","ENST00000633930;ENST00000639939;ENST00000373677;ENST00000632230;ENST00000623354;ENST00000631833;ENST00000631375;ENST00000510661","GO:0030154(cell differentiation);GO:0030154(cell differentiation)","NA","NA","NA","NHS like 2 [Source:HGNC Symbol;Acc:HGNC:33737]",{"v":8.30869032559584,"d":"8.31"},{"v":1.77284877922738,"d":"1.77"},{"v":4.68663228525155,"d":"4.69"},{"v":2.22855160491826,"d":"2.23"},{"v":3.86124138984914E-3,"d":"0.00"},{"v":0.162465928479413,"d":"0.16"},"up","yes"]
["MSTRG.5468","DDX11L10","MSTRG.5468.1;ENST00000513886;ENST00000430178","NA","NA","NA","NA","DEAD/H-box helicase 11 like 10 [Source:HGNC Symbol;Acc:HGNC:14125]",{"v":3.29282802544824,"d":"3.29"},{"v":10.6881065425101,"d":"10.69"},{"v":0.308083383371188,"d":"0.31"},{"v":-1.69860722287836,"d":"-1.70"},{"v":0.00390760675499311,"d":"0.00"},{"v":0.16350599481711,"d":"0.16"},"down","yes"]
["MSTRG.3817","MLXIP","ENST00000319080;ENST00000539861;ENST00000377037;ENST00000541750;ENST00000538698;ENST00000535996;ENST00000366272;ENST00000535430;ENST00000542417;ENST00000535876;ENST00000538061","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0046983(protein dimerization activity);GO:0006355(regulation of transcription, DNA-templated);GO:0006366(transcription from RNA polymerase II promoter);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0005739(mitochondrion);GO:0005741(mitochondrial outer membrane);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0000989(transcription factor activity, transcription factor binding);GO:1900402(regulation of carbohydrate metabolic process by regulation of transcription from RNA polymerase II promoter);GO:0001228(transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0000977(RNA polymerase II regulatory region sequence-specific DNA binding);GO:0000977(RNA polymerase II regulatory region sequence-specific DNA binding)","04932(Non-alcoholic fatty liver disease (NAFLD));04931(Insulin resistance);04931(Insulin resistance)","K09113","NA","MLX interacting protein [Source:HGNC Symbol;Acc:HGNC:17055]",{"v":5.11962789615246,"d":"5.12"},{"v":1.0935858230133,"d":"1.09"},{"v":4.68150536374519,"d":"4.68"},{"v":2.22697251091946,"d":"2.23"},{"v":0.00391411922493384,"d":"0.00"},{"v":0.16350599481711,"d":"0.16"},"up","yes"]
["MSTRG.9394","CREB1","ENST00000432329;ENST00000353267;ENST00000430624;ENST00000455757;ENST00000494983;ENST00000464407;ENST00000414681;ENST00000421139;ENST00000445803;ENST00000480189;ENST00000452474;ENST00000494094;ENST00000451164;ENST00000418081","GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0005515(protein binding);GO:0007623(circadian rhythm);GO:0048511(rhythmic process);GO:0030154(cell differentiation);GO:0045893(positive regulation of transcription, DNA-templated);GO:0042802(identical protein binding);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:0050821(protein stabilization);GO:0016032(viral process);GO:0007165(signal transduction);GO:0019899(enzyme binding);GO:0007411(axon guidance);GO:0000980(RNA polymerase II distal enhancer sequence-specific DNA binding);GO:0003712(transcription cofactor activity);GO:0001077(transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0001102(RNA polymerase II activating transcription factor binding);GO:0003705(transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding);GO:0006468(protein phosphorylation);GO:0010944(negative regulation of transcription by competitive promoter binding);GO:0001190(transcriptional activator activity, RNA polymerase II transcription factor binding);GO:0045600(positive regulation of fat cell differentiation);GO:0046889(positive regulation of lipid biosynthetic process);GO:0035497(cAMP response element binding);GO:0005719(nuclear euchromatin);GO:0010033(response to organic substance);GO:0033762(response to glucagon);GO:1990589(ATF4-CREB1 transcription factor complex);GO:0000975(regulatory region DNA binding);GO:0001225(RNA polymerase II transcription coactivator binding);GO:0003690(double-stranded DNA binding);GO:0008134(transcription factor binding);GO:0030544(Hsp70 protein binding);GO:0035035(histone acetyltransferase binding);GO:0043565(sequence-specific DNA binding);GO:0044212(transcription regulatory region DNA binding);GO:1990763(arrestin family protein binding);GO:0001666(response to hypoxia);GO:0006366(transcription from RNA polymerase II promoter);GO:0007179(transforming growth factor beta receptor signaling pathway);GO:0007409(axonogenesis);GO:0007568(aging);GO:0007595(lactation);GO:0007613(memory);GO:0008361(regulation of cell size);GO:0008542(visual learning);GO:0010629(negative regulation of gene expression);GO:0014823(response to activity);GO:0021983(pituitary gland development);GO:0030879(mammary gland development);GO:0032916(positive regulation of transforming growth factor beta3 production);GO:0033363(secretory granule organization);GO:0034670(chemotaxis to arachidonic acid);GO:0035094(response to nicotine);GO:0035729(cellular response to hepatocyte growth factor stimulus);GO:0036120(cellular response to platelet-derived growth factor stimulus);GO:0040018(positive regulation of multicellular organism growth);GO:0042493(response to drug);GO:0042752(regulation of circadian rhythm);GO:0042981(regulation of apoptotic process);GO:0043065(positive regulation of apoptotic process);GO:0045672(positive regulation of osteoclast differentiation);GO:0045899(positive regulation of RNA polymerase II transcriptional preinitiation complex assembly);GO:0046887(positive regulation of hormone secretion);GO:0048145(regulation of fibroblast proliferation);GO:0055025(positive regulation of cardiac muscle tissue development);GO:0060251(regulation of glial cell proliferation);GO:0060428(lung epithelium development);GO:0060430(lung saccule development);GO:0060509(Type I pneumocyte differentiation);GO:0071294(cellular response to zinc ion);GO:0071363(cellular response to growth factor stimulus);GO:0071398(cellular response to fatty acid);GO:0071560(cellular response to transforming growth factor beta stimulus);GO:1900273(positive regulation of long-term synaptic potentiation);GO:1901215(negative regulation of neuron death);GO:1902065(response to L-glutamate);GO:1990090(cellular response to nerve growth factor stimulus);GO:1990314(cellular response to insulin-like growth factor stimulus);GO:1990830(cellular response to leukemia inhibitory factor);GO:0000785(chromatin);GO:0000790(nuclear chromatin);GO:0005667(transcription factor complex);GO:0005739(mitochondrion);GO:0005759(mitochondrial matrix);GO:0030424(axon);GO:0030424(axon)","04668(TNF signaling pathway);04024(cAMP signaling pathway);04022(cGMP - PKG signaling pathway);04151(PI3K-Akt signaling pathway);04152(AMPK signaling pathway);04612(Antigen processing and presentation);04911(Insulin secretion);04922(Glucagon signaling pathway);04915(Estrogen signaling pathway);04926(Relaxin signaling pathway);04918(Thyroid hormone synthesis);04916(Melanogenesis);04924(Renin secretion);04925(Aldosterone synthesis and secretion);04927(Cortisol synthesis and secretion);04261(Adrenergic signaling in cardiomyocytes);04962(Vasopressin-regulated water reabsorption);04725(Cholinergic synapse);04728(Dopaminergic synapse);04380(Osteoclast differentiation);04211(Longevity regulating pathway - mammal);04710(Circadian rhythm);04713(Circadian entrainment);05203(Viral carcinogenesis);05215(Prostate cancer);05016(Huntington's disease);05030(Cocaine addiction);05031(Amphetamine addiction);05034(Alcoholism);04931(Insulin resistance);05152(Tuberculosis);05166(HTLV-I infection);05161(Hepatitis B);05167(Kaposi's sarcoma-associated herpesvirus infection);05165(Human papillomavirus infection);05165(Human papillomavirus infection)","K05870","NA","cAMP responsive element binding protein 1 [Source:HGNC Symbol;Acc:HGNC:2345]",{"v":10.4174668413577,"d":"10.42"},{"v":2.2288509986423,"d":"2.23"},{"v":4.67391801771562,"d":"4.67"},{"v":2.22463242892767,"d":"2.22"},{"v":0.0039437904995231,"d":"0.00"},{"v":0.164002608552224,"d":"0.16"},"up","yes"]
["MSTRG.8135","ZFP36","ENST00000597629;ENST00000594045;ENST00000600033","GO:0046872(metal ion binding);GO:0005515(protein binding);GO:0003729(mRNA binding);GO:0017091(AU-rich element binding);GO:0035925(mRNA 3'-UTR AU-rich region binding);GO:0070063(RNA polymerase binding);GO:0071889(14-3-3 protein binding);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0000165(MAPK cascade);GO:0000288(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay);GO:0000289(nuclear-transcribed mRNA poly(A) tail shortening);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0009611(response to wounding);GO:0035278(miRNA mediated inhibition of translation);GO:0035556(intracellular signal transduction);GO:0038066(p38MAPK cascade);GO:0043488(regulation of mRNA stability);GO:0044344(cellular response to fibroblast growth factor stimulus);GO:0045085(negative regulation of interleukin-2 biosynthetic process);GO:0045600(positive regulation of fat cell differentiation);GO:0045638(negative regulation of myeloid cell differentiation);GO:0050728(negative regulation of inflammatory response);GO:0050779(RNA destabilization);GO:0060213(positive regulation of nuclear-transcribed mRNA poly(A) tail shortening);GO:0061014(positive regulation of mRNA catabolic process);GO:0061158(3'-UTR-mediated mRNA destabilization);GO:0071222(cellular response to lipopolysaccharide);GO:0071356(cellular response to tumor necrosis factor);GO:1900153(positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay);GO:1904246(negative regulation of polynucleotide adenylyltransferase activity);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0030014(CCR4-NOT complex);GO:0030529(intracellular ribonucleoprotein complex);GO:1990904(ribonucleoprotein complex);GO:1990904(ribonucleoprotein complex)","05166(HTLV-I infection);05167(Kaposi's sarcoma-associated herpesvirus infection);05167(Kaposi's sarcoma-associated herpesvirus infection)","K15308","NA","ZFP36 ring finger protein [Source:HGNC Symbol;Acc:HGNC:12862]",{"v":10.5767984706468,"d":"10.58"},{"v":33.9695641721393,"d":"33.97"},{"v":0.311361029451227,"d":"0.31"},{"v":-1.68333970967329,"d":"-1.68"},{"v":0.00396355354083213,"d":"0.00"},{"v":0.164002608552224,"d":"0.16"},"down","yes"]
["ENSG00000164916","FOXK1","ENST00000328914;ENST00000460979;ENST00000496023","GO:0005634(nucleus);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0043565(sequence-specific DNA binding);GO:0005515(protein binding);GO:0007275(multicellular organism development);GO:0030154(cell differentiation);GO:0005654(nucleoplasm);GO:0016579(protein deubiquitination);GO:0000981(RNA polymerase II transcription factor activity, sequence-specific DNA binding);GO:0007517(muscle organ development);GO:0009653(anatomical structure morphogenesis);GO:0000977(RNA polymerase II regulatory region sequence-specific DNA binding);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0045892(negative regulation of transcription, DNA-templated);GO:0045893(positive regulation of transcription, DNA-templated);GO:0045893(positive regulation of transcription, DNA-templated)","NA","NA","NA","forkhead box K1 [Source:HGNC Symbol;Acc:HGNC:23480]",{"v":2.69961138577866,"d":"2.70"},{"v":0.576027733216222,"d":"0.58"},{"v":4.68659967238993,"d":"4.69"},{"v":2.22854156560333,"d":"2.23"},{"v":0.00397281963027808,"d":"0.00"},{"v":0.164002608552224,"d":"0.16"},"up","yes"]
["MSTRG.619","LEPROT;LEPR","ENST00000371065;ENST00000371060;ENST00000475108;ENST00000471762;ENST00000497874;ENST00000488747;ENST00000616738;ENST00000613538;ENST00000349533;ENST00000484243","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005794(Golgi apparatus);GO:0000139(Golgi membrane);GO:0005768(endosome);GO:0010008(endosome membrane);GO:0005102(receptor binding);GO:1903955(positive regulation of protein targeting to mitochondrion);GO:2000009(negative regulation of protein localization to cell surface);GO:0032511(late endosome to vacuole transport via multivesicular body sorting pathway);GO:0046426(negative regulation of JAK-STAT cascade);GO:0060400(negative regulation of growth hormone receptor signaling pathway);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0004896(cytokine receptor activity);GO:0016323(basolateral plasma membrane);GO:0007275(multicellular organism development);GO:0007166(cell surface receptor signaling pathway);GO:0060259(regulation of feeding behavior);GO:0030217(T cell differentiation);GO:0001525(angiogenesis);GO:2000505(regulation of energy homeostasis);GO:0004888(transmembrane signaling receptor activity);GO:0043235(receptor complex);GO:0042593(glucose homeostasis);GO:0046850(regulation of bone remodeling);GO:0006112(energy reserve metabolic process);GO:0019953(sexual reproduction);GO:0010507(negative regulation of autophagy);GO:0044321(response to leptin);GO:0033210(leptin-mediated signaling pathway);GO:0097009(energy homeostasis);GO:0098868(bone growth);GO:0038021(leptin receptor activity);GO:0006909(phagocytosis);GO:0008203(cholesterol metabolic process);GO:0045721(negative regulation of gluconeogenesis);GO:0051346(negative regulation of hydrolase activity);GO:0060400(negative regulation of growth hormone receptor signaling pathway)","04630(Jak-STAT signaling pathway);04152(AMPK signaling pathway);04080(Neuroactive ligand-receptor interaction);04060(Cytokine-cytokine receptor interaction);04920(Adipocytokine signaling pathway);04932(Non-alcoholic fatty liver disease (NAFLD));04932(Non-alcoholic fatty liver disease (NAFLD))","K05062","NA","leptin receptor overlapping transcript [Source:HGNC Symbol;Acc:HGNC:29477];leptin receptor [Source:HGNC Symbol;Acc:HGNC:6554]",{"v":0.983681987167011,"d":"0.98"},{"v":3.16192769511008,"d":"3.16"},{"v":0.311101986515465,"d":"0.31"},{"v":-1.6845404877783,"d":"-1.68"},{"v":0.00400412148554375,"d":"0.00"},{"v":0.164002608552224,"d":"0.16"},"down","yes"]
["ENSG00000181284","TMEM102","ENST00000396568;ENST00000323206","GO:0005739(mitochondrion);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0042981(regulation of apoptotic process);GO:0005886(plasma membrane);GO:0007165(signal transduction);GO:0006915(apoptotic process);GO:0005515(protein binding);GO:0005622(intracellular);GO:0043234(protein complex);GO:0009986(cell surface);GO:2000406(positive regulation of T cell migration);GO:0034097(response to cytokine);GO:0045785(positive regulation of cell adhesion);GO:0010820(positive regulation of T cell chemotaxis);GO:0050730(regulation of peptidyl-tyrosine phosphorylation);GO:1901028(regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway);GO:1901028(regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway)","NA","NA","NA","transmembrane protein 102 [Source:HGNC Symbol;Acc:HGNC:26722]",{"v":0.926104548614373,"d":"0.93"},{"v":3.04909646782527,"d":"3.05"},{"v":0.303730812844667,"d":"0.30"},{"v":-1.71913482061557,"d":"-1.72"},{"v":0.00401610209566836,"d":"0.00"},{"v":0.164002608552224,"d":"0.16"},"down","yes"]
["MSTRG.4696","TNFAIP2","MSTRG.4696.4;MSTRG.4696.2;ENST00000333007;ENST00000558056;ENST00000559255;MSTRG.4696.1;ENST00000561156;ENST00000560428;MSTRG.4696.5;ENST00000559406;ENST00000561217;ENST00000560562;ENST00000560869;MSTRG.4696.3","GO:0006887(exocytosis);GO:0000145(exocyst);GO:0007275(multicellular organism development);GO:0030154(cell differentiation);GO:0000149(SNARE binding);GO:0005615(extracellular space);GO:0001525(angiogenesis);GO:0051601(exocyst localization);GO:0051601(exocyst localization)","NA","NA","NA","TNF alpha induced protein 2 [Source:HGNC Symbol;Acc:HGNC:11895]",{"v":59.002237469729,"d":"59.00"},{"v":12.703053154334,"d":"12.70"},{"v":4.64472885005592,"d":"4.64"},{"v":2.21559437742649,"d":"2.22"},{"v":0.00404004859426581,"d":"0.00"},{"v":0.164002608552224,"d":"0.16"},"up","yes"]
["ENSG00000054523","KIF1B","ENST00000377093;ENST00000377086;ENST00000465635;ENST00000470616;ENST00000377083;ENST00000483340;ENST00000495136;ENST00000635499","GO:0005737(cytoplasm);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:1904115(axon cytoplasm);GO:0005739(mitochondrion);GO:0003777(microtubule motor activity);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0008017(microtubule binding);GO:0006915(apoptotic process);GO:0005874(microtubule);GO:0030659(cytoplasmic vesicle membrane);GO:0031410(cytoplasmic vesicle);GO:0007018(microtubule-based movement);GO:0005875(microtubule associated complex);GO:0030705(cytoskeleton-dependent intracellular transport);GO:0016887(ATPase activity);GO:0005871(kinesin complex);GO:0043005(neuron projection);GO:0008089(anterograde axonal transport);GO:0019894(kinesin binding);GO:0007270(neuron-neuron synaptic transmission);GO:0007274(neuromuscular synaptic transmission);GO:0019900(kinase binding);GO:0097110(scaffold protein binding);GO:1990939(ATP-dependent microtubule motor activity);GO:0010628(positive regulation of gene expression);GO:0010970(transport along microtubule);GO:0032418(lysosome localization);GO:0047497(mitochondrion transport along microtubule);GO:1904647(response to rotenone);GO:1990090(cellular response to nerve growth factor stimulus);GO:1990778(protein localization to cell periphery);GO:0016020(membrane);GO:0003774(motor activity);GO:0003774(motor activity)","NA","NA","NA","kinesin family member 1B [Source:HGNC Symbol;Acc:HGNC:16636]",{"v":1.98379218352144,"d":"1.98"},{"v":0.423873020428894,"d":"0.42"},{"v":4.68015676372643,"d":"4.68"},{"v":2.22655685426658,"d":"2.23"},{"v":0.00404553690777323,"d":"0.00"},{"v":0.164002608552224,"d":"0.16"},"up","yes"]
["MSTRG.5805","APOBR","ENST00000564831;ENST00000431282","GO:0006810(transport);GO:0016020(membrane);GO:0006629(lipid metabolic process);GO:0008202(steroid metabolic process);GO:0005886(plasma membrane);GO:0006869(lipid transport);GO:0008203(cholesterol metabolic process);GO:0034361(very-low-density lipoprotein particle);GO:0042627(chylomicron);GO:0006898(receptor-mediated endocytosis);GO:0034362(low-density lipoprotein particle);GO:0034447(very-low-density lipoprotein particle clearance);GO:0030228(lipoprotein particle receptor activity);GO:0030229(very-low-density lipoprotein particle receptor activity);GO:0006641(triglyceride metabolic process);GO:0006641(triglyceride metabolic process)","NA","NA","NA","apolipoprotein B receptor [Source:HGNC Symbol;Acc:HGNC:24087]",{"v":45.993824,"d":"45.99"},{"v":9.905704,"d":"9.91"},{"v":4.6431655942879,"d":"4.64"},{"v":2.21510873423169,"d":"2.22"},{"v":0.00405240760945415,"d":"0.00"},{"v":0.164002608552224,"d":"0.16"},"up","yes"]
["MSTRG.3016","CCND2","ENST00000261254;ENST00000536537;ENST00000536795","GO:0008284(positive regulation of cell proliferation);GO:0043066(negative regulation of apoptotic process);GO:1900087(positive regulation of G1/S transition of mitotic cell cycle);GO:0001934(positive regulation of protein phosphorylation);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005654(nucleoplasm);GO:0051301(cell division);GO:0005829(cytosol);GO:0005515(protein binding);GO:0007049(cell cycle);GO:0005730(nucleolus);GO:0031965(nuclear membrane);GO:0000785(chromatin);GO:0019901(protein kinase binding);GO:0000307(cyclin-dependent protein kinase holoenzyme complex);GO:0045737(positive regulation of cyclin-dependent protein serine/threonine kinase activity);GO:0007616(long-term memory);GO:0008344(adult locomotory behavior);GO:0051726(regulation of cell cycle);GO:0071481(cellular response to X-ray);GO:0097129(cyclin D2-CDK4 complex);GO:0097129(cyclin D2-CDK4 complex)","04310(Wnt signaling pathway);04340(Hedgehog signaling pathway);04390(Hippo signaling pathway);04630(Jak-STAT signaling pathway);04068(FoxO signaling pathway);04151(PI3K-Akt signaling pathway);04110(Cell cycle);04115(p53 signaling pathway);04218(Cellular senescence);04510(Focal adhesion);04917(Prolactin signaling pathway);05200(Pathways in cancer);05202(Transcriptional misregulation in cancers);05206(MicroRNAs in cancer);05203(Viral carcinogenesis);05166(HTLV-I infection);05162(Measles);05165(Human papillomavirus infection);05165(Human papillomavirus infection)","K10151","NA","cyclin D2 [Source:HGNC Symbol;Acc:HGNC:1583]",{"v":1.45878944026827,"d":"1.46"},{"v":4.68116180871874,"d":"4.68"},{"v":0.311629783348068,"d":"0.31"},{"v":-1.68209497241464,"d":"-1.68"},{"v":0.00405793001818373,"d":"0.00"},{"v":0.164002608552224,"d":"0.16"},"down","yes"]
["MSTRG.4646","TCL1A","ENST00000554012;ENST00000402399;ENST00000554119;ENST00000555202;ENST00000557043;ENST00000556156;ENST00000553467","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005783(endoplasmic reticulum);GO:0005515(protein binding);GO:0042802(identical protein binding);GO:0043231(intracellular membrane-bounded organelle);GO:0019901(protein kinase binding);GO:0043539(protein serine/threonine kinase activator activity);GO:0033138(positive regulation of peptidyl-serine phosphorylation);GO:0071902(positive regulation of protein serine/threonine kinase activity);GO:0043234(protein complex);GO:0071356(cellular response to tumor necrosis factor);GO:0008284(positive regulation of cell proliferation);GO:0043066(negative regulation of apoptotic process);GO:0007275(multicellular organism development);GO:0032461(positive regulation of protein oligomerization);GO:0070207(protein homotrimerization);GO:0010918(positive regulation of mitochondrial membrane potential);GO:0010918(positive regulation of mitochondrial membrane potential)","04151(PI3K-Akt signaling pathway);04151(PI3K-Akt signaling pathway)","K10167","NA","T-cell leukemia/lymphoma 1A [Source:HGNC Symbol;Acc:HGNC:11648]",{"v":3.05024206261181,"d":"3.05"},{"v":9.90118356216458,"d":"9.90"},{"v":0.308068428734895,"d":"0.31"},{"v":-1.69867725425439,"d":"-1.70"},{"v":0.00406723079850517,"d":"0.00"},{"v":0.164002608552224,"d":"0.16"},"down","yes"]
["MSTRG.12863","LTB","ENST00000446745;ENST00000429299;ENST00000482429;ENST00000483972","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0006955(immune response);GO:0005125(cytokine activity);GO:0005615(extracellular space);GO:0005164(tumor necrosis factor receptor binding);GO:0005886(plasma membrane);GO:0005575(cellular_component);GO:0033209(tumor necrosis factor-mediated signaling pathway);GO:0007165(signal transduction);GO:0007267(cell-cell signaling);GO:0045084(positive regulation of interleukin-12 biosynthetic process);GO:0005102(receptor binding);GO:0010467(gene expression);GO:0043588(skin development);GO:0048535(lymph node development);GO:0048535(lymph node development)","04064(NF-kappa B signaling pathway);04060(Cytokine-cytokine receptor interaction);05323(Rheumatoid arthritis);05323(Rheumatoid arthritis)","K03157","NA","lymphotoxin beta [Source:HGNC Symbol;Acc:HGNC:6711]",{"v":24.7665018117264,"d":"24.77"},{"v":79.077368504886,"d":"79.08"},{"v":0.31319329765249,"d":"0.31"},{"v":-1.67487475565233,"d":"-1.67"},{"v":0.00408143973949954,"d":"0.00"},{"v":0.164006088909371,"d":"0.16"},"down","yes"]
["MSTRG.1029","DPM3","ENST00000368400;ENST00000368399","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0006486(protein glycosylation);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005515(protein binding);GO:0006506(GPI anchor biosynthetic process);GO:0031647(regulation of protein stability);GO:0005975(carbohydrate metabolic process);GO:0004582(dolichyl-phosphate beta-D-mannosyltransferase activity);GO:0018279(protein N-linked glycosylation via asparagine);GO:0035268(protein mannosylation);GO:0035269(protein O-linked mannosylation);GO:0033185(dolichol-phosphate-mannose synthase complex);GO:0030176(integral component of endoplasmic reticulum membrane);GO:0018406(protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan);GO:0031501(mannosyltransferase complex);GO:0031501(mannosyltransferase complex)","00510(N-Glycan biosynthesis);00510(N-Glycan biosynthesis)","K09659","NA","dolichyl-phosphate mannosyltransferase subunit 3 [Source:HGNC Symbol;Acc:HGNC:3007]",{"v":3.31086797749196,"d":"3.31"},{"v":10.8462494935691,"d":"10.85"},{"v":0.305254639352988,"d":"0.31"},{"v":-1.71191487298939,"d":"-1.71"},{"v":0.00419313950116555,"d":"0.00"},{"v":0.167913548369088,"d":"0.17"},"down","yes"]
["MSTRG.14592","CHRAC1","ENST00000220913;ENST00000519618;ENST00000519533;ENST00000523569;ENST00000518971","GO:0005634(nucleus);GO:0016740(transferase activity);GO:0003677(DNA binding);GO:0046982(protein heterodimerization activity);GO:0005515(protein binding);GO:0016779(nucleotidyltransferase activity);GO:0003887(DNA-directed DNA polymerase activity);GO:0071897(DNA biosynthetic process);GO:0006338(chromatin remodeling);GO:0008622(epsilon DNA polymerase complex);GO:0008623(CHRAC);GO:0008623(CHRAC)","NA","NA","NA","chromatin accessibility complex 1 [Source:HGNC Symbol;Acc:HGNC:13544]",{"v":6.19306639745532,"d":"6.19"},{"v":1.3194202541654,"d":"1.32"},{"v":4.69377848180203,"d":"4.69"},{"v":2.2307497569129,"d":"2.23"},{"v":0.00423681474214475,"d":"0.00"},{"v":0.168657889296971,"d":"0.17"},"up","yes"]
["ENSG00000157741","UBN2","ENST00000473989;ENST00000609762;ENST00000483726","GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005615(extracellular space);GO:0005615(extracellular space)","NA","NA","NA","ubinuclein 2 [Source:HGNC Symbol;Acc:HGNC:21931]",{"v":1.66394142878067,"d":"1.66"},{"v":0.358010556450629,"d":"0.36"},{"v":4.64774403659277,"d":"4.65"},{"v":2.21653061794498,"d":"2.22"},{"v":0.00424077358776504,"d":"0.00"},{"v":0.168657889296971,"d":"0.17"},"up","yes"]
["ENSG00000198832","SELENOM","ENST00000400299;ENST00000611680;ENST00000469262;ENST00000491958;ENST00000490967;ENST00000465447;ENST00000402395;ENST00000495533","GO:0005737(cytoplasm);GO:0005794(Golgi apparatus);GO:0005783(endoplasmic reticulum);GO:0005515(protein binding);GO:0048471(perinuclear region of cytoplasm);GO:0010269(response to selenium ion);GO:0035264(multicellular organism growth);GO:0035934(corticosterone secretion);GO:0042445(hormone metabolic process);GO:0060612(adipose tissue development);GO:0060612(adipose tissue development)","NA","NA","NA","selenoprotein M [Source:HGNC Symbol;Acc:HGNC:30397]",{"v":0.498407007844368,"d":"0.50"},{"v":1.65062686068403,"d":"1.65"},{"v":0.301950137681526,"d":"0.30"},{"v":-1.72761776407483,"d":"-1.73"},{"v":0.0042831072551784,"d":"0.00"},{"v":0.169760152062753,"d":"0.17"},"down","yes"]
["MSTRG.2476","TMEM223","ENST00000307366;ENST00000525631;ENST00000528367","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005739(mitochondrion);GO:0007399(nervous system development);GO:0007399(nervous system development)","NA","NA","NA","transmembrane protein 223 [Source:HGNC Symbol;Acc:HGNC:28464]",{"v":1.0256615,"d":"1.03"},{"v":3.31353833684211,"d":"3.31"},{"v":0.309536632969058,"d":"0.31"},{"v":-1.69181793560834,"d":"-1.69"},{"v":0.00438878374124797,"d":"0.00"},{"v":0.173356957779295,"d":"0.17"},"down","yes"]
["MSTRG.5569","SRRM2","ENST00000301740;ENST00000574331;ENST00000572721;ENST00000572278;ENST00000570655;ENST00000576894;ENST00000575870;ENST00000572883;ENST00000573498;ENST00000574593;ENST00000573311;ENST00000570705;ENST00000576878;ENST00000570971;ENST00000630499;ENST00000572952;ENST00000576674;ENST00000571041;ENST00000574866;ENST00000574340;ENST00000571372;ENST00000576924;ENST00000573583;ENST00000571378;ENST00000576415;ENST00000575009;ENST00000573451;MSTRG.5569.2;ENST00000576076;ENST00000575701","GO:0016607(nuclear speck);GO:0003723(RNA binding);GO:0006397(mRNA processing);GO:0008380(RNA splicing);GO:0005634(nucleus);GO:0005681(spliceosomal complex);GO:0005654(nucleoplasm);GO:0000398(mRNA splicing, via spliceosome);GO:0047485(protein N-terminus binding);GO:0015030(Cajal body);GO:0071013(catalytic step 2 spliceosome);GO:0070742(C2H2 zinc finger domain binding);GO:0070742(C2H2 zinc finger domain binding)","NA","NA","NA","serine/arginine repetitive matrix 2 [Source:HGNC Symbol;Acc:HGNC:16639]",{"v":20.6273660433439,"d":"20.63"},{"v":4.50492355759083,"d":"4.50"},{"v":4.57884929225639,"d":"4.58"},{"v":2.19498508108649,"d":"2.19"},{"v":0.00445929876300094,"d":"0.00"},{"v":0.175042986504194,"d":"0.18"},"up","yes"]
["ENSG00000157240","FZD1","ENST00000287934","GO:0051091(positive regulation of sequence-specific DNA binding transcription factor activity);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005886(plasma membrane);GO:0004871(signal transducer activity);GO:0007165(signal transduction);GO:0004888(transmembrane signaling receptor activity);GO:0004930(G-protein coupled receptor activity);GO:0007166(cell surface receptor signaling pathway);GO:0007186(G-protein coupled receptor signaling pathway);GO:0007275(multicellular organism development);GO:0016055(Wnt signaling pathway);GO:0042813(Wnt-activated receptor activity);GO:0005925(focal adhesion);GO:0005515(protein binding);GO:0060071(Wnt signaling pathway, planar cell polarity pathway);GO:0017147(Wnt-protein binding);GO:0035567(non-canonical Wnt signaling pathway);GO:0009986(cell surface);GO:0045893(positive regulation of transcription, DNA-templated);GO:0030182(neuron differentiation);GO:0060070(canonical Wnt signaling pathway);GO:0005102(receptor binding);GO:0099054(presynapse assembly);GO:0030165(PDZ domain binding);GO:0005109(frizzled binding);GO:1904886(beta-catenin destruction complex disassembly);GO:0007267(cell-cell signaling);GO:1990909(Wnt signalosome);GO:1904953(Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation);GO:0042493(response to drug);GO:0044338(canonical Wnt signaling pathway involved in mesenchymal stem cell differentiation);GO:0044339(canonical Wnt signaling pathway involved in osteoblast differentiation);GO:0001934(positive regulation of protein phosphorylation);GO:0003149(membranous septum morphogenesis);GO:0003150(muscular septum morphogenesis);GO:0003151(outflow tract morphogenesis);GO:0030514(negative regulation of BMP signaling pathway);GO:0030855(epithelial cell differentiation);GO:0035414(negative regulation of catenin import into nucleus);GO:0035425(autocrine signaling);GO:0045892(negative regulation of transcription, DNA-templated);GO:0060022(hard palate development);GO:0060412(ventricular septum morphogenesis);GO:0090179(planar cell polarity pathway involved in neural tube closure);GO:1903204(negative regulation of oxidative stress-induced neuron death)","04310(Wnt signaling pathway);04390(Hippo signaling pathway);04150(mTOR signaling pathway);04550(Signaling pathways regulating pluripotency of stem cells);04916(Melanogenesis);05200(Pathways in cancer);05205(Proteoglycans in cancer);05225(Hepatocellular carcinoma);05226(Gastric cancer);05217(Basal cell carcinoma);05224(Breast cancer);05166(HTLV-I infection);05165(Human papillomavirus infection)","K02432","NA","frizzled class receptor 1 [Source:HGNC Symbol;Acc:HGNC:4038]",{"v":0.950552,"d":"0.95"},{"v":0.20097,"d":"0.20"},{"v":4.72982037119968,"d":"4.73"},{"v":2.24178539402971,"d":"2.24"},{"v":4.46161405366756E-3,"d":"0.00"},{"v":0.175042986504194,"d":"0.18"},"up","yes"]
["ENSG00000070444","MNT","ENST00000174618;ENST00000575402;ENST00000573384;ENST00000575374;ENST00000571836;ENST00000571232;ENST00000574559","GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0046983(protein dimerization activity);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0003713(transcription coactivator activity);GO:0007275(multicellular organism development);GO:0003714(transcription corepressor activity);GO:0006366(transcription from RNA polymerase II promoter);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0000977(RNA polymerase II regulatory region sequence-specific DNA binding);GO:0008285(negative regulation of cell proliferation);GO:0001227(transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding);GO:0003682(chromatin binding);GO:0007569(cell aging);GO:0051726(regulation of cell cycle);GO:2001234(negative regulation of apoptotic signaling pathway);GO:2001234(negative regulation of apoptotic signaling pathway)","NA","NA","NA","MAX network transcriptional repressor [Source:HGNC Symbol;Acc:HGNC:7188]",{"v":2.78512724003208,"d":"2.79"},{"v":0.602650839367553,"d":"0.60"},{"v":4.62146081627449,"d":"4.62"},{"v":2.20834895105122,"d":"2.21"},{"v":0.00448236183413133,"d":"0.00"},{"v":0.175123752965711,"d":"0.18"},"up","yes"]
["MSTRG.2562","AP5B1","MSTRG.2562.1;ENST00000532090","GO:0006810(transport);GO:0015031(protein transport);GO:0005765(lysosomal membrane);GO:0005515(protein binding);GO:0016197(endosomal transport);GO:0030119(AP-type membrane coat adaptor complex)","NA","NA","NA","adaptor related protein complex 5 beta 1 subunit [Source:HGNC Symbol;Acc:HGNC:25104]",{"v":3.55632227245135,"d":"3.56"},{"v":0.768324119264417,"d":"0.77"},{"v":4.62867451806163,"d":"4.63"},{"v":2.21059911789276,"d":"2.21"},{"v":0.0044938326344426,"d":"0.00"},{"v":0.175123752965711,"d":"0.18"},"up","yes"]
["MSTRG.11220","RNF7","ENST00000273480;ENST00000480908;ENST00000477393;ENST00000498828;ENST00000477012;ENST00000393000","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0016567(protein ubiquitination);GO:0005515(protein binding);GO:0061630(ubiquitin protein ligase activity);GO:0043687(post-translational protein modification);GO:0031463(Cul3-RING ubiquitin ligase complex);GO:0042787(protein ubiquitination involved in ubiquitin-dependent protein catabolic process);GO:0080008(Cul4-RING E3 ubiquitin ligase complex);GO:0005507(copper ion binding);GO:0031146(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process);GO:0019788(NEDD8 transferase activity);GO:0045116(protein neddylation);GO:0097602(cullin family protein binding);GO:0043224(nuclear SCF ubiquitin ligase complex);GO:0031462(Cul2-RING ubiquitin ligase complex);GO:0031466(Cul5-RING ubiquitin ligase complex);GO:0051775(response to redox state);GO:0031467(Cul7-RING ubiquitin ligase complex);GO:0004842(ubiquitin-protein transferase activity);GO:0005680(anaphase-promoting complex);GO:0005680(anaphase-promoting complex)","04120(Ubiquitin mediated proteolysis);04120(Ubiquitin mediated proteolysis)","K10611","NA","ring finger protein 7 [Source:HGNC Symbol;Acc:HGNC:10070]",{"v":1.26123669367652,"d":"1.26"},{"v":4.03799270829361,"d":"4.04"},{"v":0.312342489149639,"d":"0.31"},{"v":-1.67879925682594,"d":"-1.68"},{"v":0.00452878426688367,"d":"0.00"},{"v":0.175491792424128,"d":"0.18"},"down","yes"]
["MSTRG.12816","ZNRD1ASP","ENST00000437417;ENST00000431012;ENST00000376797;ENST00000421692;ENST00000448093;ENST00000420251;ENST00000444051;ENST00000452229;ENST00000425604","NA","NA","NA","NA","zinc ribbon domain containing 1 antisense, pseudogene [Source:HGNC Symbol;Acc:HGNC:13924]",{"v":0.343767734348272,"d":"0.34"},{"v":0.0712341293191926,"d":"0.07"},{"v":4.82588525519678,"d":"4.83"},{"v":2.27079361308234,"d":"2.27"},{"v":0.00453350019178838,"d":"0.00"},{"v":0.175491792424128,"d":"0.18"},"up","yes"]
["MSTRG.958","SNX27","ENST00000458013;ENST00000368843;ENST00000368838;ENST00000368841;ENST00000482791","GO:0006810(transport);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0006886(intracellular protein transport);GO:0015031(protein transport);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0007165(signal transduction);GO:0035091(phosphatidylinositol binding);GO:0032266(phosphatidylinositol-3-phosphate binding);GO:0016197(endosomal transport);GO:0008289(lipid binding);GO:0005515(protein binding);GO:0005768(endosome);GO:0005769(early endosome);GO:1990126(retrograde transport, endosome to plasma membrane);GO:0031901(early endosome membrane);GO:0071203(WASH complex);GO:0001772(immunological synapse);GO:0030904(retromer complex);GO:0001770(establishment of natural killer cell polarity);GO:0008333(endosome to lysosome transport);GO:0008333(endosome to lysosome transport)","NA","NA","NA","sorting nexin family member 27 [Source:HGNC Symbol;Acc:HGNC:20073]",{"v":9.13415705410473,"d":"9.13"},{"v":1.99871826663988,"d":"2.00"},{"v":4.57000729245373,"d":"4.57"},{"v":2.19219646742305,"d":"2.19"},{"v":0.00456227103324927,"d":"0.00"},{"v":0.176018782422338,"d":"0.18"},"up","yes"]
["MSTRG.6719","CCL3L3","ENST00000612839;ENST00000616702;ENST00000619989","GO:0005576(extracellular region);GO:0006955(immune response);GO:0005125(cytokine activity);GO:0005615(extracellular space);GO:0008009(chemokine activity);GO:0006935(chemotaxis);GO:0006954(inflammatory response);GO:0007186(G-protein coupled receptor signaling pathway);GO:0048020(CCR chemokine receptor binding);GO:0002548(monocyte chemotaxis);GO:0030593(neutrophil chemotaxis);GO:0043547(positive regulation of GTPase activity);GO:0048247(lymphocyte chemotaxis);GO:0070098(chemokine-mediated signaling pathway);GO:0070374(positive regulation of ERK1 and ERK2 cascade);GO:0071346(cellular response to interferon-gamma);GO:0071347(cellular response to interleukin-1);GO:0071356(cellular response to tumor necrosis factor);GO:0008285(negative regulation of cell proliferation);GO:0008285(negative regulation of cell proliferation)","04060(Cytokine-cytokine receptor interaction);04620(Toll-like receptor signaling pathway);04062(Chemokine signaling pathway);05323(Rheumatoid arthritis);05132(Salmonella infection);05142(Chagas disease (American trypanosomiasis));05142(Chagas disease (American trypanosomiasis))","K05408","NA","C-C motif chemokine ligand 3 like 3 [Source:HGNC Symbol;Acc:HGNC:30554]",{"v":4.91479499795779,"d":"4.91"},{"v":1.04586503607897,"d":"1.05"},{"v":4.69926312517697,"d":"4.70"},{"v":2.2324345506205,"d":"2.23"},{"v":4.59787770584067E-3,"d":"0.00"},{"v":0.176675674104593,"d":"0.18"},"up","yes"]
["MSTRG.14993","SWI5","ENST00000418976;ENST00000495313;ENST00000419867;ENST00000608796;ENST00000320188","GO:0005634(nucleus);GO:0006281(DNA repair);GO:0006974(cellular response to DNA damage stimulus);GO:0005515(protein binding);GO:0000724(double-strand break repair via homologous recombination);GO:0071479(cellular response to ionizing radiation);GO:0000730(DNA recombinase assembly);GO:0032798(Swi5-Sfr1 complex);GO:0032798(Swi5-Sfr1 complex)","NA","NA","NA","SWI5 homologous recombination repair protein [Source:HGNC Symbol;Acc:HGNC:31412]",{"v":0.889919946027896,"d":"0.89"},{"v":2.89977832686477,"d":"2.90"},{"v":0.30689240545848,"d":"0.31"},{"v":-1.70419515042854,"d":"-1.70"},{"v":0.00460972438247582,"d":"0.00"},{"v":0.176675674104593,"d":"0.18"},"down","yes"]
["MSTRG.7912","ADGRE2","ENST00000596991;ENST00000594294;ENST00000594076;ENST00000392965;ENST00000601619;ENST00000598500;ENST00000360222;ENST00000392962;ENST00000599423;ENST00000595208;ENST00000315576;ENST00000601345","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0004930(G-protein coupled receptor activity);GO:0007186(G-protein coupled receptor signaling pathway);GO:0005509(calcium ion binding);GO:0007155(cell adhesion);GO:0005886(plasma membrane);GO:0042995(cell projection);GO:0004871(signal transducer activity);GO:0007165(signal transduction);GO:0004888(transmembrane signaling receptor activity);GO:0007166(cell surface receptor signaling pathway);GO:0006954(inflammatory response);GO:0032587(ruffle membrane);GO:0016477(cell migration);GO:0035374(chondroitin sulfate binding);GO:0071621(granulocyte chemotaxis);GO:0043304(regulation of mast cell degranulation);GO:0031256(leading edge membrane);GO:0031256(leading edge membrane)","NA","NA","NA","adhesion G protein-coupled receptor E2 [Source:HGNC Symbol;Acc:HGNC:3337]",{"v":16.3146567562051,"d":"16.31"},{"v":3.58537433866852,"d":"3.59"},{"v":4.55033567353075,"d":"4.55"},{"v":2.18597297534991,"d":"2.19"},{"v":0.00464076623213226,"d":"0.00"},{"v":0.177195592412731,"d":"0.18"},"up","yes"]
["ENSG00000162971","TYW5","ENST00000354611;ENST00000483328;ENST00000493181","GO:0046872(metal ion binding);GO:0008033(tRNA processing);GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0042803(protein homodimerization activity);GO:0051213(dioxygenase activity);GO:0000049(tRNA binding);GO:0005506(iron ion binding);GO:0016706(oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors);GO:0006400(tRNA modification);GO:0031591(wybutosine biosynthetic process);GO:0005737(cytoplasm);GO:0005737(cytoplasm)","NA","NA","NA","tRNA-yW synthesizing protein 5 [Source:HGNC Symbol;Acc:HGNC:26754]",{"v":0.658820704458841,"d":"0.66"},{"v":0.138503830983232,"d":"0.14"},{"v":4.75669661829499,"d":"4.76"},{"v":2.24996001326782,"d":"2.25"},{"v":0.00466486428001072,"d":"0.00"},{"v":0.177195592412731,"d":"0.18"},"up","yes"]
["ENSG00000149639","SOGA1","ENST00000237536;ENST00000279034;ENST00000463491","GO:0005615(extracellular space);GO:0010506(regulation of autophagy);GO:0005576(extracellular region);GO:0003674(molecular_function);GO:0070062(extracellular exosome);GO:0045721(negative regulation of gluconeogenesis);GO:0008286(insulin receptor signaling pathway);GO:0008286(insulin receptor signaling pathway)","NA","NA","NA","suppressor of glucose, autophagy associated 1 [Source:HGNC Symbol;Acc:HGNC:16111]",{"v":0.922022181517716,"d":"0.92"},{"v":0.199160436541512,"d":"0.20"},{"v":4.62954489118894,"d":"4.63"},{"v":2.21087037588367,"d":"2.21"},{"v":0.00468242983949106,"d":"0.00"},{"v":0.177195592412731,"d":"0.18"},"up","yes"]
["ENSG00000116128","BCL9","ENST00000234739;ENST00000473292;ENST00000497938","GO:0005634(nucleus);GO:0003713(transcription coactivator activity);GO:0008013(beta-catenin binding);GO:0014908(myotube differentiation involved in skeletal muscle regeneration);GO:0035019(somatic stem cell population maintenance);GO:0035914(skeletal muscle cell differentiation);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0060070(canonical Wnt signaling pathway);GO:0005737(cytoplasm);GO:0005794(Golgi apparatus);GO:0005801(cis-Golgi network);GO:0005515(protein binding);GO:0016055(Wnt signaling pathway);GO:0005654(nucleoplasm);GO:1904837(beta-catenin-TCF complex assembly);GO:1904837(beta-catenin-TCF complex assembly)","NA","NA","NA","B-cell CLL/lymphoma 9 [Source:HGNC Symbol;Acc:HGNC:1008]",{"v":1.9247745376947,"d":"1.92"},{"v":0.416118859813084,"d":"0.42"},{"v":4.6255402568374,"d":"4.63"},{"v":2.20962188029715,"d":"2.21"},{"v":0.00468952349831634,"d":"0.00"},{"v":0.177195592412731,"d":"0.18"},"up","yes"]
["ENSG00000080200","CRYBG3","ENST00000389622","GO:0030246(carbohydrate binding)","NA","NA","NA","crystallin beta-gamma domain containing 3 [Source:HGNC Symbol;Acc:HGNC:34427]",{"v":1.26725207018025,"d":"1.27"},{"v":0.275163656052704,"d":"0.28"},{"v":4.60544858416013,"d":"4.61"},{"v":2.20334168587667,"d":"2.20"},{"v":0.00472679294711966,"d":"0.00"},{"v":0.177195592412731,"d":"0.18"},"up","yes"]
["ENSG00000168564","CDKN2AIP","ENST00000504169;ENST00000302350;ENST00000510928;ENST00000506835","GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0006974(cellular response to DNA damage stimulus);GO:0005515(protein binding);GO:0030307(positive regulation of cell growth);GO:0031647(regulation of protein stability);GO:0005730(nucleolus);GO:0030308(negative regulation of cell growth);GO:0002039(p53 binding);GO:0009967(positive regulation of signal transduction);GO:0001652(granular component);GO:0001652(granular component)","NA","NA","NA","CDKN2A interacting protein [Source:HGNC Symbol;Acc:HGNC:24325]",{"v":6.89739478860006,"d":"6.90"},{"v":1.50010720137801,"d":"1.50"},{"v":4.5979345891174,"d":"4.60"},{"v":2.20098594221373,"d":"2.20"},{"v":0.00472838557232159,"d":"0.00"},{"v":0.177195592412731,"d":"0.18"},"up","yes"]
["ENSG00000162972","MAIP1","ENST00000392290;ENST00000295079;ENST00000469156;ENST00000435773","GO:0005739(mitochondrion);GO:0005759(mitochondrial matrix);GO:0005515(protein binding);GO:0005743(mitochondrial inner membrane);GO:0043022(ribosome binding);GO:0006851(mitochondrial calcium ion transmembrane transport);GO:0051560(mitochondrial calcium ion homeostasis);GO:0036444(mitochondrial calcium uptake);GO:0051204(protein insertion into mitochondrial membrane);GO:0007007(inner mitochondrial membrane organization);GO:0032979(protein insertion into mitochondrial membrane from inner side);GO:0097033(mitochondrial respiratory chain complex III biogenesis);GO:0097034(mitochondrial respiratory chain complex IV biogenesis);GO:0097034(mitochondrial respiratory chain complex IV biogenesis)","NA","NA","NA","matrix AAA peptidase interacting protein 1 [Source:HGNC Symbol;Acc:HGNC:26198]",{"v":0.801051644704433,"d":"0.80"},{"v":2.62927116995074,"d":"2.63"},{"v":0.304666804192525,"d":"0.30"},{"v":-1.71469577909598,"d":"-1.71"},{"v":0.00473009847997473,"d":"0.00"},{"v":0.177195592412731,"d":"0.18"},"down","yes"]
["MSTRG.8317","PRR12","ENST00000418929;ENST00000593853;ENST00000615927","GO:0005634(nucleus);GO:0016020(membrane);GO:0005886(plasma membrane);GO:0030054(cell junction);GO:0045202(synapse);GO:0045211(postsynaptic membrane);GO:0014069(postsynaptic density);GO:0043005(neuron projection);GO:0043005(neuron projection)","NA","NA","NA","proline rich 12 [Source:HGNC Symbol;Acc:HGNC:29217]",{"v":3.85921849739179,"d":"3.86"},{"v":0.845986079233047,"d":"0.85"},{"v":4.56179905571316,"d":"4.56"},{"v":2.18960289826973,"d":"2.19"},{"v":0.00476058946405352,"d":"0.00"},{"v":0.17776439050178,"d":"0.18"},"up","yes"]
["MSTRG.15134","MT-ND6","MSTRG.15134.1","NA","NA","NA","NA",null,{"v":53.04406,"d":"53.04"},{"v":11.641379,"d":"11.64"},{"v":4.55651001483587,"d":"4.56"},{"v":2.18792923841867,"d":"2.19"},{"v":0.00477678918785117,"d":"0.00"},{"v":0.177797605251653,"d":"0.18"},"up","yes"]
["MSTRG.14620","AC067930.6;AC067930.2","ENST00000623257;ENST00000529247","NA","NA","NA","NA",null,{"v":0.732387865979381,"d":"0.73"},{"v":2.323712,"d":"2.32"},{"v":0.315180136772277,"d":"0.32"},{"v":-1.66575147850395,"d":"-1.67"},{"v":4.81018855322552E-3,"d":"0.00"},{"v":0.17846875293485,"d":"0.18"},"down","yes"]
["MSTRG.6169","CMIP","MSTRG.6169.1","NA","NA","NA","NA",null,{"v":6.674108,"d":"6.67"},{"v":20.939783,"d":"20.94"},{"v":0.318728613376748,"d":"0.32"},{"v":-1.64959955420354,"d":"-1.65"},{"v":0.00487052278760776,"d":"0.00"},{"v":0.179613874083452,"d":"0.18"},"down","yes"]
["ENSG00000186111","PIP5K1C","ENST00000539785;ENST00000335312;ENST00000537021;ENST00000592530;ENST00000637724","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0007155(cell adhesion);GO:0005886(plasma membrane);GO:0042995(cell projection);GO:0005515(protein binding);GO:0045202(synapse);GO:0030054(cell junction);GO:0098793(presynapse);GO:0005925(focal adhesion);GO:0006935(chemotaxis);GO:0016307(phosphatidylinositol phosphate kinase activity);GO:0046488(phosphatidylinositol metabolic process);GO:0046854(phosphatidylinositol phosphorylation);GO:0030593(neutrophil chemotaxis);GO:0006887(exocytosis);GO:0006897(endocytosis);GO:0001891(phagocytic cup);GO:0061024(membrane organization);GO:0032587(ruffle membrane);GO:0012505(endomembrane system);GO:0005912(adherens junction);GO:0006909(phagocytosis);GO:0006661(phosphatidylinositol biosynthetic process);GO:0014066(regulation of phosphatidylinositol 3-kinase signaling);GO:0072583(clathrin-dependent endocytosis);GO:0030036(actin cytoskeleton organization);GO:0016308(1-phosphatidylinositol-4-phosphate 5-kinase activity);GO:0052811(1-phosphatidylinositol-3-phosphate 4-kinase activity);GO:0052812(phosphatidylinositol-3,4-bisphosphate 5-kinase activity);GO:0001931(uropod);GO:0016337(single organismal cell-cell adhesion);GO:0016079(synaptic vesicle exocytosis);GO:0034333(adherens junction assembly);GO:0048488(synaptic vesicle endocytosis);GO:0048488(synaptic vesicle endocytosis)","00562(Inositol phosphate metabolism);04070(Phosphatidylinositol signaling system);04072(Phospholipase D signaling pathway);04144(Endocytosis);04510(Focal adhesion);04810(Regulation of actin cytoskeleton);04666(Fc gamma R-mediated phagocytosis);05231(Choline metabolism in cancer);05231(Choline metabolism in cancer)","K00889","EC:2.7.1.68","phosphatidylinositol-4-phosphate 5-kinase type 1 gamma [Source:HGNC Symbol;Acc:HGNC:8996]",{"v":2.09471785695821,"d":"2.09"},{"v":0.456589317391929,"d":"0.46"},{"v":4.58775047327736,"d":"4.59"},{"v":2.19778692562683,"d":"2.20"},{"v":0.00490224925828214,"d":"0.00"},{"v":0.179613874083452,"d":"0.18"},"up","yes"]
["MSTRG.7118","HELZ","ENST00000358691;ENST00000580168;ENST00000579861;ENST00000417253;ENST00000579953;ENST00000578938;ENST00000582864;ENST00000580963;ENST00000584641;ENST00000581159","GO:0003723(RNA binding);GO:0005634(nucleus);GO:0016020(membrane);GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0016787(hydrolase activity);GO:0004386(helicase activity);GO:0016021(integral component of membrane);GO:0016021(integral component of membrane)","NA","NA","NA","helicase with zinc finger [Source:HGNC Symbol;Acc:HGNC:16878]",{"v":5.7385357544173,"d":"5.74"},{"v":1.27118567506538,"d":"1.27"},{"v":4.51431751236668,"d":"4.51"},{"v":2.17450789336521,"d":"2.17"},{"v":0.00490487773272242,"d":"0.00"},{"v":0.179613874083452,"d":"0.18"},"up","yes"]
["ENSG00000124813","RUNX2","ENST00000359524;ENST00000371432;ENST00000625924;ENST00000478660;ENST00000483243;ENST00000483377;ENST00000465038","GO:0030509(BMP signaling pathway);GO:0005634(nucleus);GO:0005524(ATP binding);GO:0005654(nucleoplasm);GO:0006355(regulation of transcription, DNA-templated);GO:0006366(transcription from RNA polymerase II promoter);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0005515(protein binding);GO:0045893(positive regulation of transcription, DNA-templated);GO:0000981(RNA polymerase II transcription factor activity, sequence-specific DNA binding);GO:0030182(neuron differentiation);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0001503(ossification);GO:0071773(cellular response to BMP stimulus);GO:0045892(negative regulation of transcription, DNA-templated);GO:0000790(nuclear chromatin);GO:1901522(positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus);GO:0001649(osteoblast differentiation);GO:0030097(hemopoiesis);GO:0002062(chondrocyte differentiation);GO:0045595(regulation of cell differentiation);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:0000979(RNA polymerase II core promoter sequence-specific DNA binding);GO:0001077(transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0003682(chromatin binding);GO:0019904(protein domain specific binding);GO:0043425(bHLH transcription factor binding);GO:0044212(transcription regulatory region DNA binding);GO:0070491(repressing transcription factor binding);GO:0001501(skeletal system development);GO:0001958(endochondral ossification);GO:0002051(osteoblast fate commitment);GO:0002063(chondrocyte development);GO:0002076(osteoblast development);GO:0008284(positive regulation of cell proliferation);GO:0010628(positive regulation of gene expression);GO:0030217(T cell differentiation);GO:0030278(regulation of ossification);GO:0032332(positive regulation of chondrocyte differentiation);GO:0035115(embryonic forelimb morphogenesis);GO:0040036(regulation of fibroblast growth factor receptor signaling pathway);GO:0042475(odontogenesis of dentin-containing tooth);GO:0042487(regulation of odontogenesis of dentin-containing tooth);GO:0045667(regulation of osteoblast differentiation);GO:0045669(positive regulation of osteoblast differentiation);GO:0045879(negative regulation of smoothened signaling pathway);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0048469(cell maturation);GO:0048701(embryonic cranial skeleton morphogenesis);GO:0048705(skeletal system morphogenesis);GO:0048863(stem cell differentiation);GO:0005667(transcription factor complex);GO:0005737(cytoplasm);GO:0005737(cytoplasm)","05202(Transcriptional misregulation in cancers);05202(Transcriptional misregulation in cancers)","K09278","NA","runt related transcription factor 2 [Source:HGNC Symbol;Acc:HGNC:10472]",{"v":3.56003809545898,"d":"3.56"},{"v":0.781353035522461,"d":"0.78"},{"v":4.55624785930283,"d":"4.56"},{"v":2.18784623160716,"d":"2.19"},{"v":4.91711605480107E-3,"d":"0.00"},{"v":0.179613874083452,"d":"0.18"},"up","yes"]
["ENSG00000100354","TNRC6B","ENST00000301923;ENST00000335727;ENST00000446273;ENST00000497559;ENST00000467658;ENST00000454349;ENST00000441751","GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0005737(cytoplasm);GO:0005515(protein binding);GO:0035278(miRNA mediated inhibition of translation);GO:0031047(gene silencing by RNA);GO:0000932(P-body);GO:0005829(cytosol);GO:0006417(regulation of translation);GO:0060213(positive regulation of nuclear-transcribed mRNA poly(A) tail shortening);GO:1900153(positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay);GO:0038111(interleukin-7-mediated signaling pathway);GO:0048015(phosphatidylinositol-mediated signaling);GO:0045652(regulation of megakaryocyte differentiation);GO:0007223(Wnt signaling pathway, calcium modulating pathway);GO:0035194(posttranscriptional gene silencing by RNA);GO:0035194(posttranscriptional gene silencing by RNA)","NA","NA","NA","trinucleotide repeat containing 6B [Source:HGNC Symbol;Acc:HGNC:29190]",{"v":5.96104602695269,"d":"5.96"},{"v":1.32228347314731,"d":"1.32"},{"v":4.50814530167587,"d":"4.51"},{"v":2.17253401564965,"d":"2.17"},{"v":0.00491838559877188,"d":"0.00"},{"v":0.179613874083452,"d":"0.18"},"up","yes"]
["ENSG00000165288","BRWD3","ENST00000373275;ENST00000487313;ENST00000497335;ENST00000473691;ENST00000478415","GO:0005634(nucleus);GO:0007010(cytoskeleton organization);GO:0008360(regulation of cell shape);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0006357(regulation of transcription from RNA polymerase II promoter)","NA","NA","NA","bromodomain and WD repeat domain containing 3 [Source:HGNC Symbol;Acc:HGNC:17342]",{"v":5.76395850614464,"d":"5.76"},{"v":1.28164626989129,"d":"1.28"},{"v":4.49730837716521,"d":"4.50"},{"v":2.16906181194858,"d":"2.17"},{"v":0.0049928482816787,"d":"0.00"},{"v":0.181761589639921,"d":"0.18"},"up","yes"]
["MSTRG.14863","TSTD2","ENST00000341170;ENST00000375172;ENST00000375165;ENST00000375163;ENST00000375173;ENST00000484708","GO:0005515(protein binding);GO:0003674(molecular_function);GO:0008150(biological_process);GO:0005575(cellular_component);GO:0005575(cellular_component)","NA","NA","NA","thiosulfate sulfurtransferase like domain containing 2 [Source:HGNC Symbol;Acc:HGNC:30087]",{"v":1.70561070995745,"d":"1.71"},{"v":0.367237447489362,"d":"0.37"},{"v":4.6444356958092,"d":"4.64"},{"v":2.21550331817654,"d":"2.22"},{"v":0.0051098771290581,"d":"0.01"},{"v":0.185001308390003,"d":"0.19"},"up","yes"]
["ENSG00000105810","CDK6","ENST00000473078;ENST00000265734;ENST00000491250;ENST00000424848","GO:0005737(cytoplasm);GO:0050680(negative regulation of epithelial cell proliferation);GO:0005634(nucleus);GO:0048146(positive regulation of fibroblast proliferation);GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0051301(cell division);GO:0005856(cytoskeleton);GO:0042995(cell projection);GO:0005515(protein binding);GO:0007049(cell cycle);GO:0030154(cell differentiation);GO:0005813(centrosome);GO:0005815(microtubule organizing center);GO:0008285(negative regulation of cell proliferation);GO:0042127(regulation of cell proliferation);GO:0007165(signal transduction);GO:0009615(response to virus);GO:0007050(cell cycle arrest);GO:0001726(ruffle);GO:0045786(negative regulation of cell cycle);GO:0045638(negative regulation of myeloid cell differentiation);GO:0003323(type B pancreatic cell development);GO:0014002(astrocyte development);GO:0045596(negative regulation of cell differentiation);GO:0001954(positive regulation of cell-matrix adhesion);GO:0048699(generation of neurons);GO:2000145(regulation of cell motility);GO:0045668(negative regulation of osteoblast differentiation);GO:0004693(cyclin-dependent protein serine/threonine kinase activity);GO:0045656(negative regulation of monocyte differentiation);GO:0010468(regulation of gene expression);GO:0000082(G1/S transition of mitotic cell cycle);GO:0000307(cyclin-dependent protein kinase holoenzyme complex);GO:0045646(regulation of erythrocyte differentiation);GO:0010389(regulation of G2/M transition of mitotic cell cycle);GO:0021670(lateral ventricle development);GO:1904628(cellular response to phorbol 13-acetate 12-myristate);GO:0030332(cyclin binding);GO:0098770(FBXO family protein binding);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0002244(hematopoietic progenitor cell differentiation);GO:0007219(Notch signaling pathway);GO:0010628(positive regulation of gene expression);GO:0021542(dentate gyrus development);GO:0030097(hemopoiesis);GO:0033077(T cell differentiation in thymus);GO:0042063(gliogenesis);GO:0043697(cell dedifferentiation);GO:0060218(hematopoietic stem cell differentiation);GO:1902036(regulation of hematopoietic stem cell differentiation);GO:2000773(negative regulation of cellular senescence);GO:0097132(cyclin D2-CDK6 complex);GO:0097132(cyclin D2-CDK6 complex)","04151(PI3K-Akt signaling pathway);04110(Cell cycle);04115(p53 signaling pathway);04218(Cellular senescence);05200(Pathways in cancer);05206(MicroRNAs in cancer);05203(Viral carcinogenesis);05212(Pancreatic cancer);05225(Hepatocellular carcinoma);05214(Glioma);05220(Chronic myeloid leukemia);05218(Melanoma);05224(Breast cancer);05222(Small cell lung cancer);05223(Non-small cell lung cancer);05162(Measles);05161(Hepatitis B);05167(Kaposi's sarcoma-associated herpesvirus infection);05165(Human papillomavirus infection);05165(Human papillomavirus infection)","K02091","EC:2.7.11.22","cyclin dependent kinase 6 [Source:HGNC Symbol;Acc:HGNC:1777]",{"v":0.312556001957586,"d":"0.31"},{"v":0.981508562153344,"d":"0.98"},{"v":0.318444498611266,"d":"0.32"},{"v":-1.65088614644247,"d":"-1.65"},{"v":0.0051137018852313,"d":"0.01"},{"v":0.185001308390003,"d":"0.19"},"down","yes"]
["ENSG00000167595","PROSER3","ENST00000620918;ENST00000544158;ENST00000536037;ENST00000601095;ENST00000600988;ENST00000542591;ENST00000537459;ENST00000542134;ENST00000545674;ENST00000301165;ENST00000396908","NA","NA","NA","NA","proline and serine rich 3 [Source:HGNC Symbol;Acc:HGNC:25204]",{"v":0.651718850798167,"d":"0.65"},{"v":0.136515477951636,"d":"0.14"},{"v":4.77395574902543,"d":"4.77"},{"v":2.25518519378512,"d":"2.26"},{"v":0.00515139137288565,"d":"0.01"},{"v":0.185560982392153,"d":"0.19"},"up","yes"]
["ENSG00000166847","DCTN5","ENST00000300087;ENST00000568589;ENST00000563614;ENST00000566298;ENST00000563188;ENST00000563998;ENST00000568272","GO:0005737(cytoplasm);GO:0005654(nucleoplasm);GO:0031965(nuclear membrane);GO:0005694(chromosome);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0005813(centrosome);GO:0000775(chromosome, centromeric region);GO:0000776(kinetochore);GO:0000777(condensed chromosome kinetochore);GO:0005829(cytosol);GO:0019886(antigen processing and presentation of exogenous peptide antigen via MHC class II);GO:0006888(ER to Golgi vesicle-mediated transport);GO:0003281(ventricular septum development);GO:0035904(aorta development);GO:0060976(coronary vasculature development);GO:0060976(coronary vasculature development)","04962(Vasopressin-regulated water reabsorption);04962(Vasopressin-regulated water reabsorption)","K10427","NA","dynactin subunit 5 [Source:HGNC Symbol;Acc:HGNC:24594]",{"v":2.15496439073783,"d":"2.15"},{"v":0.479158859968603,"d":"0.48"},{"v":4.4973902619249,"d":"4.50"},{"v":2.16908807958498,"d":"2.17"},{"v":0.00518365628737019,"d":"0.01"},{"v":0.185560982392153,"d":"0.19"},"up","yes"]
["MSTRG.4517","ELMSAN1","MSTRG.4517.4;ENST00000486739;ENST00000394071;ENST00000478847;ENST00000435371;ENST00000286523;ENST00000451078;ENST00000462716;ENST00000483269","GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0008134(transcription factor binding);GO:0005667(transcription factor complex);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0044212(transcription regulatory region DNA binding);GO:0000118(histone deacetylase complex);GO:0003676(nucleic acid binding);GO:0003676(nucleic acid binding)","NA","NA","NA","ELM2 and Myb/SANT domain containing 1 [Source:HGNC Symbol;Acc:HGNC:19853]",{"v":2.88936726512904,"d":"2.89"},{"v":0.641624289676654,"d":"0.64"},{"v":4.50320742468327,"d":"4.50"},{"v":2.1709529319702,"d":"2.17"},{"v":0.00521134099776537,"d":"0.01"},{"v":0.185560982392153,"d":"0.19"},"up","yes"]
["MSTRG.15464","CD40LG","ENST00000370629","GO:0005622(intracellular);GO:2000353(positive regulation of endothelial cell apoptotic process);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005886(plasma membrane);GO:0005576(extracellular region);GO:0006955(immune response);GO:0005125(cytokine activity);GO:0005615(extracellular space);GO:0005164(tumor necrosis factor receptor binding);GO:0006954(inflammatory response);GO:0050776(regulation of immune response);GO:0005515(protein binding);GO:0033209(tumor necrosis factor-mediated signaling pathway);GO:0042102(positive regulation of T cell proliferation);GO:0005887(integral component of plasma membrane);GO:0043066(negative regulation of apoptotic process);GO:0032753(positive regulation of interleukin-4 production);GO:0051092(positive regulation of NF-kappaB transcription factor activity);GO:0009986(cell surface);GO:0030168(platelet activation);GO:0045190(isotype switching);GO:0042100(B cell proliferation);GO:0032735(positive regulation of interleukin-12 production);GO:0007159(leukocyte cell-cell adhesion);GO:0032733(positive regulation of interleukin-10 production);GO:0031295(T cell costimulation);GO:0005174(CD40 receptor binding);GO:0007257(activation of JUN kinase activity);GO:0030183(B cell differentiation);GO:0048305(immunoglobulin secretion);GO:0051023(regulation of immunoglobulin secretion);GO:0009897(external side of plasma membrane)","04064(NF-kappa B signaling pathway);04060(Cytokine-cytokine receptor interaction);04514(Cell adhesion molecules (CAMs));04660(T cell receptor signaling pathway);04672(Intestinal immune network for IgA production);05310(Asthma);05322(Systemic lupus erythematosus);05320(Autoimmune thyroid disease);05330(Allograft rejection);05340(Primary immunodeficiency);05416(Viral myocarditis);05144(Malaria);05145(Toxoplasmosis)","K03161","NA","CD40 ligand [Source:HGNC Symbol;Acc:HGNC:11935]",{"v":1.90876,"d":"1.91"},{"v":5.957879,"d":"5.96"},{"v":0.320375757882965,"d":"0.32"},{"v":-1.64216310851775,"d":"-1.64"},{"v":0.00521460763010348,"d":"0.01"},{"v":0.185560982392153,"d":"0.19"},"down","yes"]
["ENSG00000073910","FRY","ENST00000542859;ENST00000380217;ENST00000463566;ENST00000642040;ENST00000380250;ENST00000418076;ENST00000641614","GO:0005737(cytoplasm);GO:0005856(cytoskeleton);GO:0043086(negative regulation of catalytic activity);GO:0000922(spindle pole);GO:0005815(microtubule organizing center);GO:0005938(cell cortex);GO:0000902(cell morphogenesis);GO:0031175(neuron projection development);GO:0090527(actin filament reorganization);GO:0030427(site of polarized growth);GO:0004857(enzyme inhibitor activity);GO:1904428(negative regulation of tubulin deacetylation);GO:1904428(negative regulation of tubulin deacetylation)","NA","NA","NA","FRY microtubule binding protein [Source:HGNC Symbol;Acc:HGNC:20367]",{"v":5.50140655278783,"d":"5.50"},{"v":1.2320261044895,"d":"1.23"},{"v":4.46533278210642,"d":"4.47"},{"v":2.15876769722873,"d":"2.16"},{"v":0.00522060858688666,"d":"0.01"},{"v":0.185560982392153,"d":"0.19"},"up","yes"]
["MSTRG.1357","CR1","ENST00000367053;ENST00000400960;ENST00000367049;ENST00000367052;ENST00000450439;ENST00000529814;ENST00000367051;ENST00000530487;ENST00000436595;ENST00000534202;ENST00000367050;ENST00000434033","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0002376(immune system process);GO:0045087(innate immune response);GO:0030449(regulation of complement activation);GO:0005886(plasma membrane);GO:0005887(integral component of plasma membrane);GO:0046718(viral entry into host cell);GO:0070062(extracellular exosome);GO:0016032(viral process);GO:0002430(complement receptor mediated signaling pathway);GO:0043312(neutrophil degranulation);GO:0006958(complement activation, classical pathway);GO:0009986(cell surface);GO:0030667(secretory granule membrane);GO:0001618(virus receptor activity);GO:0101003(ficolin-1-rich granule membrane);GO:0045589(regulation of regulatory T cell differentiation);GO:1900005(positive regulation of serine-type endopeptidase activity);GO:1900004(negative regulation of serine-type endopeptidase activity);GO:0001851(complement component C3b binding);GO:0001855(complement component C4b binding);GO:0001861(complement component C4b receptor activity);GO:0004877(complement component C3b receptor activity);GO:0045957(negative regulation of complement activation, alternative pathway);GO:0045959(negative regulation of complement activation, classical pathway);GO:0045959(negative regulation of complement activation, classical pathway)","04640(Hematopoietic cell lineage);04610(Complement and coagulation cascades);05134(Legionellosis);05152(Tuberculosis);05144(Malaria);05140(Leishmaniasis);05140(Leishmaniasis)","K04011","NA","complement C3b/C4b receptor 1 (Knops blood group) [Source:HGNC Symbol;Acc:HGNC:2334]",{"v":16.2786693255124,"d":"16.28"},{"v":3.64803703078936,"d":"3.65"},{"v":4.46230923319055,"d":"4.46"},{"v":2.15779049424812,"d":"2.16"},{"v":5.22504445382194E-3,"d":"0.01"},{"v":0.185560982392153,"d":"0.19"},"up","yes"]
["MSTRG.8551","PTRHD1","ENST00000328379;ENST00000487316;ENST00000492046","GO:0016787(hydrolase activity);GO:0004045(aminoacyl-tRNA hydrolase activity);GO:0070062(extracellular exosome);GO:0070062(extracellular exosome)","NA","NA","NA","peptidyl-tRNA hydrolase domain containing 1 [Source:HGNC Symbol;Acc:HGNC:33782]",{"v":3.08428729786124,"d":"3.08"},{"v":9.54173955399061,"d":"9.54"},{"v":0.323241614425675,"d":"0.32"},{"v":-1.62931515094128,"d":"-1.63"},{"v":0.00528227551094075,"d":"0.01"},{"v":0.187021541184619,"d":"0.19"},"down","yes"]
["MSTRG.5189","PLEKHO2;ANKDD1A;AC069368.1","ENST00000323544;ENST00000319580;ENST00000620154;ENST00000502574;ENST00000491145;ENST00000616065;ENST00000395720","GO:0005576(extracellular region);GO:0043312(neutrophil degranulation);GO:1904813(ficolin-1-rich granule lumen);GO:0007165(signal transduction);GO:0007165(signal transduction)","04060(Cytokine-cytokine receptor interaction);04060(Cytokine-cytokine receptor interaction)","NA","NA","pleckstrin homology domain containing O2 [Source:HGNC Symbol;Acc:HGNC:30026];ankyrin repeat and death domain containing 1A [Source:HGNC Symbol;Acc:HGNC:28002]",{"v":5.09897716695558,"d":"5.10"},{"v":15.5577479921993,"d":"15.56"},{"v":0.327745196124286,"d":"0.33"},{"v":-1.60935346037004,"d":"-1.61"},{"v":0.00541281377426647,"d":"0.01"},{"v":0.191060809606555,"d":"0.19"},"down","yes"]
["ENSG00000273136","NBPF26","ENST00000609741;ENST00000617913;ENST00000620612;ENST00000619748;ENST00000615145;ENST00000615219;ENST00000611702;ENST00000611287;ENST00000624419","GO:0005509(calcium ion binding);GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0055114(oxidation-reduction process)","NA","NA","NA","NBPF member 26 [Source:HGNC Symbol;Acc:HGNC:49571]",{"v":4.78494566865474,"d":"4.78"},{"v":1.07133074867462,"d":"1.07"},{"v":4.46635707467032,"d":"4.47"},{"v":2.15909859582296,"d":"2.16"},{"v":0.00545691657827674,"d":"0.01"},{"v":0.192033855222811,"d":"0.19"},"up","yes"]
["ENSG00000176014","TUBB6","ENST00000586691;ENST00000590967;ENST00000591909;ENST00000586653;ENST00000586810;ENST00000590693;ENST00000317702;ENST00000417736;ENST00000587204","GO:0005525(GTP binding);GO:0003924(GTPase activity);GO:0005200(structural constituent of cytoskeleton);GO:0007010(cytoskeleton organization);GO:0005874(microtubule);GO:0007017(microtubule-based process);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0000166(nucleotide binding);GO:0015630(microtubule cytoskeleton);GO:0005856(cytoskeleton);GO:0003674(molecular_function);GO:0070062(extracellular exosome);GO:0070062(extracellular exosome)","04145(Phagosome);04540(Gap junction);05130(Pathogenic Escherichia coli infection);05130(Pathogenic Escherichia coli infection)","K07375","NA","tubulin beta 6 class V [Source:HGNC Symbol;Acc:HGNC:20776]",{"v":0.381696914743745,"d":"0.38"},{"v":1.22516656060238,"d":"1.23"},{"v":0.311546957791662,"d":"0.31"},{"v":-1.68247846561103,"d":"-1.68"},{"v":0.00550826695649837,"d":"0.01"},{"v":0.193255299594609,"d":"0.19"},"down","yes"]
["ENSG00000198040","ZNF84","ENST00000539354;ENST00000545299;ENST00000438628;ENST00000543124;ENST00000392319;ENST00000543758;ENST00000542874;ENST00000539686;ENST00000540031;ENST00000539098;ENST00000542358;ENST00000543310","GO:0003676(nucleic acid binding);GO:0046872(metal ion binding);GO:0006355(regulation of transcription, DNA-templated);GO:0005622(intracellular);GO:0005634(nucleus);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0008270(zinc ion binding);GO:0001570(vasculogenesis);GO:0001822(kidney development);GO:0006807(nitrogen compound metabolic process);GO:0009791(post-embryonic development);GO:0014909(smooth muscle cell migration);GO:0030097(hemopoiesis);GO:0035264(multicellular organism growth);GO:0048008(platelet-derived growth factor receptor signaling pathway);GO:0048705(skeletal system morphogenesis);GO:0048745(smooth muscle tissue development);GO:0060021(palate development);GO:0060325(face morphogenesis);GO:0060325(face morphogenesis)","NA","NA","NA","zinc finger protein 84 [Source:HGNC Symbol;Acc:HGNC:13159]",{"v":0.535175650210084,"d":"0.54"},{"v":0.112840133298319,"d":"0.11"},{"v":4.74277754347581,"d":"4.74"},{"v":2.24573220144489,"d":"2.25"},{"v":0.00554412575298863,"d":"0.01"},{"v":0.193413827912954,"d":"0.19"},"up","yes"]
["ENSG00000121406","ZNF549","ENST00000376233;ENST00000594943;ENST00000602149;ENST00000240719","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0005622(intracellular);GO:0005622(intracellular)","NA","NA","NA","zinc finger protein 549 [Source:HGNC Symbol;Acc:HGNC:26632]",{"v":0.799713698997737,"d":"0.80"},{"v":0.174139956999677,"d":"0.17"},{"v":4.59236187246343,"d":"4.59"},{"v":2.19923632908646,"d":"2.20"},{"v":0.00554609529794315,"d":"0.01"},{"v":0.193413827912954,"d":"0.19"},"up","yes"]
["MSTRG.15033","TOR1A","MSTRG.15033.1;ENST00000351698;ENST00000474192;ENST00000473084;ENST00000473604","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0043231(intracellular membrane-bounded organelle);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0016787(hydrolase activity);GO:0031965(nuclear membrane);GO:0007155(cell adhesion);GO:0005783(endoplasmic reticulum);GO:0005856(cytoskeleton);GO:0042995(cell projection);GO:0005515(protein binding);GO:0031175(neuron projection development);GO:0008092(cytoskeletal protein binding);GO:0030054(cell junction);GO:0045202(synapse);GO:0030659(cytoplasmic vesicle membrane);GO:0031410(cytoplasmic vesicle);GO:0051082(unfolded protein binding);GO:0006998(nuclear envelope organization);GO:0045104(intermediate filament cytoskeleton organization);GO:0005635(nuclear envelope);GO:0005788(endoplasmic reticulum lumen);GO:0005829(cytosol);GO:0030426(growth cone);GO:0070062(extracellular exosome);GO:0016887(ATPase activity);GO:0061077(chaperone-mediated protein folding);GO:0019894(kinesin binding);GO:0051787(misfolded protein binding);GO:0000338(protein deneddylation);GO:0006979(response to oxidative stress);GO:0006996(organelle organization);GO:0034504(protein localization to nucleus);GO:0044319(wound healing, spreading of cells);GO:0048489(synaptic vesicle transport);GO:0051085(chaperone mediated protein folding requiring cofactor);GO:0051260(protein homooligomerization);GO:0051584(regulation of dopamine uptake involved in synaptic transmission);GO:0071712(ER-associated misfolded protein catabolic process);GO:0071763(nuclear membrane organization);GO:0072321(chaperone-mediated protein transport);GO:1900244(positive regulation of synaptic vesicle endocytosis);GO:2000008(regulation of protein localization to cell surface);GO:0008021(synaptic vesicle);GO:0030133(transport vesicle);GO:0030141(secretory granule);GO:0042406(extrinsic component of endoplasmic reticulum membrane);GO:0043005(neuron projection);GO:0043005(neuron projection)","NA","NA","NA","torsin family 1 member A [Source:HGNC Symbol;Acc:HGNC:3098]",{"v":2.72675820028646,"d":"2.73"},{"v":8.33848080973979,"d":"8.34"},{"v":0.327008991506158,"d":"0.33"},{"v":-1.61259778998051,"d":"-1.61"},{"v":5.59431705270696E-3,"d":"0.01"},{"v":0.194511389021215,"d":"0.19"},"down","yes"]
["MSTRG.14941","STOM","ENST00000286713;ENST00000347359;ENST00000538954","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005829(cytosol);GO:0005887(integral component of plasma membrane);GO:0005886(plasma membrane);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0042470(melanosome);GO:0005615(extracellular space);GO:0031410(cytoplasmic vesicle);GO:0005783(endoplasmic reticulum);GO:0045121(membrane raft);GO:0042802(identical protein binding);GO:0042803(protein homodimerization activity);GO:0034765(regulation of ion transmembrane transport);GO:0044829(positive regulation by host of viral genome replication);GO:0048524(positive regulation of viral process);GO:0090314(positive regulation of protein targeting to membrane);GO:1901585(regulation of acid-sensing ion channel activity);GO:0005739(mitochondrion);GO:0048471(perinuclear region of cytoplasm);GO:0070062(extracellular exosome);GO:0072562(blood microparticle);GO:0043312(neutrophil degranulation);GO:0035579(specific granule membrane);GO:0070821(tertiary granule membrane);GO:0031982(vesicle);GO:0035577(azurophil granule membrane);GO:0070063(RNA polymerase binding);GO:0051260(protein homooligomerization);GO:0051260(protein homooligomerization)","NA","NA","NA","stomatin [Source:HGNC Symbol;Acc:HGNC:3383]",{"v":24.3741252195122,"d":"24.37"},{"v":5.53070259943715,"d":"5.53"},{"v":4.407057653397,"d":"4.41"},{"v":2.13981577016332,"d":"2.14"},{"v":0.00568129307699548,"d":"0.01"},{"v":0.196291872474366,"d":"0.20"},"up","yes"]
["MSTRG.11596","COMMD8","ENST00000381571;ENST00000509220","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0005515(protein binding);GO:0005515(protein binding)","NA","NA","NA","COMM domain containing 8 [Source:HGNC Symbol;Acc:HGNC:26036]",{"v":2.54604914609287,"d":"2.55"},{"v":7.80983222536806,"d":"7.81"},{"v":0.326005613516605,"d":"0.33"},{"v":-1.6170312883364,"d":"-1.62"},{"v":0.00569019413578308,"d":"0.01"},{"v":0.196291872474366,"d":"0.20"},"down","yes"]
["ENSG00000112787","FBRSL1","ENST00000542061;ENST00000434748;ENST00000536075;ENST00000542306;ENST00000543360;ENST00000537804;ENST00000543453","GO:0003723(RNA binding);GO:0003723(RNA binding)","NA","NA","NA","fibrosin like 1 [Source:HGNC Symbol;Acc:HGNC:29308]",{"v":3.5791365733004,"d":"3.58"},{"v":0.804973791322092,"d":"0.80"},{"v":4.44627714825599,"d":"4.45"},{"v":2.15259787817882,"d":"2.15"},{"v":0.00569623361955235,"d":"0.01"},{"v":0.196291872474366,"d":"0.20"},"up","yes"]
["ENSG00000157570","TSPAN18","ENST00000520358;ENST00000533080;ENST00000520837;ENST00000520245;ENST00000520999;ENST00000517621;ENST00000518429;ENST00000520278;ENST00000340160;ENST00000519051;ENST00000521990","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005887(integral component of plasma membrane);GO:0007166(cell surface receptor signaling pathway);GO:0007166(cell surface receptor signaling pathway)","NA","NA","NA","tetraspanin 18 [Source:HGNC Symbol;Acc:HGNC:20660]",{"v":1.81973811650485,"d":"1.82"},{"v":0.407229623062511,"d":"0.41"},{"v":4.46857992014376,"d":"4.47"},{"v":2.15981642700839,"d":"2.16"},{"v":0.00584314418992235,"d":"0.01"},{"v":0.200758678927717,"d":"0.20"},"up","yes"]
["MSTRG.13400","IGF2R","ENST00000356956;ENST00000475834;ENST00000464636;ENST00000487607;ENST00000475584","GO:0006810(transport);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005794(Golgi apparatus);GO:0005215(transporter activity);GO:0005765(lysosomal membrane);GO:0005515(protein binding);GO:0005925(focal adhesion);GO:0005764(lysosome);GO:0005886(plasma membrane);GO:0042802(identical protein binding);GO:0070062(extracellular exosome);GO:0061024(membrane organization);GO:0005802(trans-Golgi network);GO:0005769(early endosome);GO:0005887(integral component of plasma membrane);GO:0043312(neutrophil degranulation);GO:0007165(signal transduction);GO:0032588(trans-Golgi network membrane);GO:0004872(receptor activity);GO:0009986(cell surface);GO:0030667(secretory granule membrane);GO:0030133(transport vesicle);GO:0051219(phosphoprotein binding);GO:0030139(endocytic vesicle);GO:0030665(clathrin-coated vesicle membrane);GO:0006898(receptor-mediated endocytosis);GO:0005768(endosome);GO:0005010(insulin-like growth factor-activated receptor activity);GO:0030140(trans-Golgi network transport vesicle);GO:0005770(late endosome);GO:0001965(G-protein alpha-subunit binding);GO:0001972(retinoic acid binding);GO:0004930(G-protein coupled receptor activity);GO:0005520(insulin-like growth factor binding);GO:0005537(mannose binding);GO:0019899(enzyme binding);GO:0031995(insulin-like growth factor II binding);GO:0001889(liver development);GO:0007186(G-protein coupled receptor signaling pathway);GO:0007283(spermatogenesis);GO:0009791(post-embryonic development);GO:0031100(animal organ regeneration);GO:0032526(response to retinoic acid);GO:0042981(regulation of apoptotic process);GO:0043065(positive regulation of apoptotic process);GO:0048009(insulin-like growth factor receptor signaling pathway);GO:0005615(extracellular space);GO:0005634(nucleus);GO:0005641(nuclear envelope lumen);GO:0030118(clathrin coat);GO:0048471(perinuclear region of cytoplasm);GO:0048471(perinuclear region of cytoplasm)","04144(Endocytosis);04142(Lysosome);04142(Lysosome)","K06564","NA","insulin like growth factor 2 receptor [Source:HGNC Symbol;Acc:HGNC:5467]",{"v":55.4179144245188,"d":"55.42"},{"v":12.6814084015827,"d":"12.68"},{"v":4.37001259399566,"d":"4.37"},{"v":2.12763743745331,"d":"2.13"},{"v":0.00587241304465942,"d":"0.01"},{"v":0.20116912297236,"d":"0.20"},"up","yes"]
["ENSG00000174501","ANKRD36C","ENST00000456556;ENST00000612359;ENST00000528268;ENST00000619511;ENST00000531153;ENST00000295246","GO:0065009(regulation of molecular function);GO:0008200(ion channel inhibitor activity);GO:0008200(ion channel inhibitor activity)","NA","NA","NA","ankyrin repeat domain 36C [Source:HGNC Symbol;Acc:HGNC:32946]",{"v":0.553193561464894,"d":"0.55"},{"v":0.117936004082109,"d":"0.12"},{"v":4.69062493485663,"d":"4.69"},{"v":2.22978014669719,"d":"2.23"},{"v":0.00596047427189454,"d":"0.01"},{"v":0.203561901376032,"d":"0.20"},"up","yes"]
["MSTRG.15415","NKRF","ENST00000304449;ENST00000371527;ENST00000542113","GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005730(nucleolus);GO:0006366(transcription from RNA polymerase II promoter);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0045892(negative regulation of transcription, DNA-templated);GO:0001077(transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0001077(transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding)","NA","NA","NA","NFKB repressing factor [Source:HGNC Symbol;Acc:HGNC:19374]",{"v":1.81564701398601,"d":"1.82"},{"v":0.403074884615385,"d":"0.40"},{"v":4.50449056313321,"d":"4.50"},{"v":2.17136395318639,"d":"2.17"},{"v":5.97731924302308E-3,"d":"0.01"},{"v":0.203561901376032,"d":"0.20"},"up","yes"]
["MSTRG.15132","MT-ND5;MT-CO1","MSTRG.15132.2;MSTRG.15132.1;ENST00000361624","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0046872(metal ion binding);GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0005743(mitochondrial inner membrane);GO:0005739(mitochondrion);GO:0005506(iron ion binding);GO:0005515(protein binding);GO:1902600(hydrogen ion transmembrane transport);GO:0070469(respiratory chain);GO:0020037(heme binding);GO:0004129(cytochrome-c oxidase activity);GO:0009055(electron carrier activity);GO:0009060(aerobic respiration);GO:0006123(mitochondrial electron transport, cytochrome c to oxygen);GO:0005751(mitochondrial respiratory chain complex IV);GO:0005750(mitochondrial respiratory chain complex III);GO:0006119(oxidative phosphorylation);GO:0006979(response to oxidative stress);GO:0007568(aging);GO:0015990(electron transport coupled proton transport);GO:0021549(cerebellum development);GO:0046688(response to copper ion);GO:0051602(response to electrical stimulus);GO:0045277(respiratory chain complex IV)","NA","NA","NA","mitochondrially encoded cytochrome c oxidase I [Source:HGNC Symbol;Acc:HGNC:7419]",{"v":90.3064132097292,"d":"90.31"},{"v":270.238652793057,"d":"270.24"},{"v":0.334172821971859,"d":"0.33"},{"v":-1.5813336900365,"d":"-1.58"},{"v":0.0060551736469671,"d":"0.01"},{"v":0.205610326205348,"d":"0.21"},"down","yes"]
["MSTRG.3459","MYL6;MYL6B","ENST00000547649;ENST00000550184;ENST00000548580;ENST00000550697;ENST00000536128;ENST00000549566;ENST00000549392;ENST00000548400;ENST00000551589;ENST00000548293;ENST00000552568;ENST00000549017;ENST00000549178;ENST00000546845;ENST00000547408;ENST00000549380;ENST00000553066;ENST00000550550;ENST00000348108;ENST00000551954;ENST00000550639;ENST00000548725;ENST00000293422;ENST00000546630;ENST00000405661;ENST00000547703;ENST00000550443;ENST00000551834;ENST00000552297;ENST00000548571","GO:0016020(membrane);GO:0005509(calcium ion binding);GO:0016459(myosin complex);GO:0005515(protein binding);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0031012(extracellular matrix);GO:0005903(brush border);GO:0031982(vesicle);GO:0006936(muscle contraction);GO:0007519(skeletal muscle tissue development);GO:0030898(actin-dependent ATPase activity);GO:0030049(muscle filament sliding);GO:0003774(motor activity);GO:0008307(structural constituent of muscle);GO:0016461(unconventional myosin complex);GO:0005859(muscle myosin complex);GO:0016461(unconventional myosin complex)","04530(Tight junction);04921(Oxytocin signaling pathway);04270(Vascular smooth muscle contraction);04270(Vascular smooth muscle contraction)","K12751","NA","myosin light chain 6 [Source:HGNC Symbol;Acc:HGNC:7587];myosin light chain 6B [Source:HGNC Symbol;Acc:HGNC:29823]",{"v":21.4420278710631,"d":"21.44"},{"v":64.1276487939324,"d":"64.13"},{"v":0.334364790762326,"d":"0.33"},{"v":-1.58050515795589,"d":"-1.58"},{"v":0.00610865310350662,"d":"0.01"},{"v":0.206123498161565,"d":"0.21"},"down","yes"]
["MSTRG.6862","LSM12","ENST00000293406;ENST00000585388;ENST00000590563","NA","NA","NA","NA","LSM12 homolog [Source:HGNC Symbol;Acc:HGNC:26407]",{"v":2.22876577303451,"d":"2.23"},{"v":6.72756909498399,"d":"6.73"},{"v":0.331288425517065,"d":"0.33"},{"v":-1.59384029515341,"d":"-1.59"},{"v":0.00614730014432638,"d":"0.01"},{"v":0.206123498161565,"d":"0.21"},"down","yes"]
["ENSG00000146247","PHIP","ENST00000275034;ENST00000479165","GO:0005634(nucleus);GO:0005158(insulin receptor binding);GO:0045893(positive regulation of transcription, DNA-templated);GO:0005515(protein binding);GO:0008286(insulin receptor signaling pathway);GO:0070062(extracellular exosome);GO:0007010(cytoskeleton organization);GO:0022604(regulation of cell morphogenesis);GO:0008360(regulation of cell shape);GO:0008284(positive regulation of cell proliferation);GO:0043066(negative regulation of apoptotic process);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0045840(positive regulation of mitotic nuclear division);GO:0001932(regulation of protein phosphorylation);GO:0070577(lysine-acetylated histone binding);GO:0043568(positive regulation of insulin-like growth factor receptor signaling pathway);GO:2001237(negative regulation of extrinsic apoptotic signaling pathway);GO:2001237(negative regulation of extrinsic apoptotic signaling pathway)","NA","NA","NA","pleckstrin homology domain interacting protein [Source:HGNC Symbol;Acc:HGNC:15673]",{"v":6.02972188152732,"d":"6.03"},{"v":1.38613772909749,"d":"1.39"},{"v":4.35001641969103,"d":"4.35"},{"v":2.12102084660783,"d":"2.12"},{"v":0.00615362519147054,"d":"0.01"},{"v":0.206123498161565,"d":"0.21"},"up","yes"]
["ENSG00000179406","LINC00174","ENST00000438894;ENST00000638592;ENST00000412091;ENST00000421767;ENST00000450353;ENST00000638517;ENST00000639086;ENST00000640964","NA","NA","NA","NA","long intergenic non-protein coding RNA 174 [Source:HGNC Symbol;Acc:HGNC:27788]",{"v":0.473525062621103,"d":"0.47"},{"v":0.103166466795843,"d":"0.10"},{"v":4.58991256876293,"d":"4.59"},{"v":2.19846667263396,"d":"2.20"},{"v":0.00615500951842364,"d":"0.01"},{"v":0.206123498161565,"d":"0.21"},"up","yes"]
["MSTRG.8282","C19orf68","ENST00000614654;ENST00000593921","GO:0005634(nucleus);GO:0007275(multicellular organism development);GO:0005515(protein binding);GO:0006511(ubiquitin-dependent protein catabolic process);GO:0008270(zinc ion binding);GO:0008270(zinc ion binding)","NA","NA","NA","chromosome 19 open reading frame 68 [Source:HGNC Symbol;Acc:HGNC:34495]",{"v":0.963120729672087,"d":"0.96"},{"v":0.203435530791789,"d":"0.20"},{"v":4.73427982773479,"d":"4.73"},{"v":2.24314498155926,"d":"2.24"},{"v":0.00615903331284449,"d":"0.01"},{"v":0.206123498161565,"d":"0.21"},"up","yes"]
["MSTRG.6830","ATP6V0A1","ENST00000393829;ENST00000264649;ENST00000588629;ENST00000588806;ENST00000586001;ENST00000589759;ENST00000537728;ENST00000586201;ENST00000592831;ENST00000585828;ENST00000587375;ENST00000589213;ENST00000592324;ENST00000587882","GO:0006810(transport);GO:0016607(nuclear speck);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005794(Golgi apparatus);GO:0043231(intracellular membrane-bounded organelle);GO:0005829(cytosol);GO:0006811(ion transport);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0042470(melanosome);GO:0030659(cytoplasmic vesicle membrane);GO:0031410(cytoplasmic vesicle);GO:0015078(hydrogen ion transmembrane transporter activity);GO:0015991(ATP hydrolysis coupled proton transport);GO:0015992(proton transport);GO:0000220(vacuolar proton-transporting V-type ATPase, V0 domain);GO:0033179(proton-transporting V-type ATPase, V0 domain);GO:0070062(extracellular exosome);GO:0034220(ion transmembrane transport);GO:0010008(endosome membrane);GO:0043312(neutrophil degranulation);GO:0030670(phagocytic vesicle membrane);GO:0030667(secretory granule membrane);GO:0008286(insulin receptor signaling pathway);GO:0016241(regulation of macroautophagy);GO:0033572(transferrin transport);GO:0090383(phagosome acidification);GO:0101003(ficolin-1-rich granule membrane);GO:0051117(ATPase binding);GO:0015986(ATP synthesis coupled proton transport);GO:0005765(lysosomal membrane);GO:0046961(proton-transporting ATPase activity, rotational mechanism);GO:0070072(vacuolar proton-transporting V-type ATPase complex assembly);GO:0016471(vacuolar proton-transporting V-type ATPase complex);GO:0007035(vacuolar acidification);GO:1901998(toxin transport);GO:0005737(cytoplasm);GO:0005737(cytoplasm)","00190(Oxidative phosphorylation);04145(Phagosome);04142(Lysosome);04966(Collecting duct acid secretion);04721(Synaptic vesicle cycle);05323(Rheumatoid arthritis);05110(Vibrio cholerae infection);05120(Epithelial cell signaling in Helicobacter pylori infection);05152(Tuberculosis);05165(Human papillomavirus infection);05165(Human papillomavirus infection)","K02154","NA","ATPase H+ transporting V0 subunit a1 [Source:HGNC Symbol;Acc:HGNC:865]",{"v":2.66844651188127,"d":"2.67"},{"v":0.612313102392042,"d":"0.61"},{"v":4.35797715491765,"d":"4.36"},{"v":2.12365863367883,"d":"2.12"},{"v":0.00627254350205482,"d":"0.01"},{"v":0.209269898157207,"d":"0.21"},"up","yes"]
["MSTRG.10852","SNRK","ENST00000296088;ENST00000429705;ENST00000454177;ENST00000481892;ENST00000437827;ENST00000484791;ENST00000462810;ENST00000468628","GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0000287(magnesium ion binding);GO:0005737(cytoplasm);GO:0035556(intracellular signal transduction);GO:0030099(myeloid cell differentiation);GO:0030099(myeloid cell differentiation)","NA","NA","NA","SNF related kinase [Source:HGNC Symbol;Acc:HGNC:30598]",{"v":17.5143409798023,"d":"17.51"},{"v":4.04219568256697,"d":"4.04"},{"v":4.33287805816465,"d":"4.33"},{"v":2.1153256348658,"d":"2.12"},{"v":0.00628908933581893,"d":"0.01"},{"v":0.209269898157207,"d":"0.21"},"up","yes"]
["ENSG00000171469","ZNF561","ENST00000302851;ENST00000444802;ENST00000470932;ENST00000490893;ENST00000444611;ENST00000443819;ENST00000495503;ENST00000497409;ENST00000457965;ENST00000465974;ENST00000483768;ENST00000424629;ENST00000326044;ENST00000479943;ENST00000471053;ENST00000480167;ENST00000435550;ENST00000421525;ENST00000444519;ENST00000485150","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0005622(intracellular);GO:0005622(intracellular)","NA","NA","NA","zinc finger protein 561 [Source:HGNC Symbol;Acc:HGNC:28684]",{"v":0.90727264573991,"d":"0.91"},{"v":2.73875697665069,"d":"2.74"},{"v":0.331271687657896,"d":"0.33"},{"v":-1.59391318703429,"d":"-1.59"},{"v":0.00643114586516833,"d":"0.01"},{"v":0.212879869137449,"d":"0.21"},"down","yes"]
["MSTRG.333","SRSF4","ENST00000373795;ENST00000622143;ENST00000634348;ENST00000605204;ENST00000466448;ENST00000477193","GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0006397(mRNA processing);GO:0008380(RNA splicing);GO:0005634(nucleus);GO:0016607(nuclear speck);GO:0005515(protein binding);GO:0005654(nucleoplasm);GO:0006369(termination of RNA polymerase II transcription);GO:0006405(RNA export from nucleus);GO:0031124(mRNA 3'-end processing);GO:0048025(negative regulation of mRNA splicing, via spliceosome);GO:0000398(mRNA splicing, via spliceosome);GO:0006406(mRNA export from nucleus);GO:1990825(sequence-specific mRNA binding);GO:0000375(RNA splicing, via transesterification reactions);GO:0032868(response to insulin);GO:0032868(response to insulin)","03040(Spliceosome);05168(Herpes simplex infection);05168(Herpes simplex infection)","K12893","NA","serine and arginine rich splicing factor 4 [Source:HGNC Symbol;Acc:HGNC:10786]",{"v":7.52811594782413,"d":"7.53"},{"v":1.7404855770831,"d":"1.74"},{"v":4.32529636955716,"d":"4.33"},{"v":2.1127989896838,"d":"2.11"},{"v":0.00643424042600918,"d":"0.01"},{"v":0.212879869137449,"d":"0.21"},"up","yes"]
["MSTRG.9584","TMEM230","ENST00000202834;ENST00000379299;ENST00000379283;ENST00000379277;ENST00000492419;ENST00000379279;ENST00000342308;ENST00000612323;ENST00000379276;ENST00000615008;ENST00000379286","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005783(endoplasmic reticulum);GO:0005794(Golgi apparatus);GO:0030054(cell junction);GO:0045202(synapse);GO:0031410(cytoplasmic vesicle);GO:0005768(endosome);GO:0005802(trans-Golgi network);GO:0005769(early endosome);GO:0005770(late endosome);GO:0005776(autophagosome);GO:0055037(recycling endosome);GO:0048489(synaptic vesicle transport);GO:0008021(synaptic vesicle);GO:0008021(synaptic vesicle)","NA","NA","NA","transmembrane protein 230 [Source:HGNC Symbol;Acc:HGNC:15876]",{"v":7.88955270337594,"d":"7.89"},{"v":23.4315280239266,"d":"23.43"},{"v":0.336706709665699,"d":"0.34"},{"v":-1.57043562437526,"d":"-1.57"},{"v":0.00648289959345829,"d":"0.01"},{"v":0.213880434598952,"d":"0.21"},"down","yes"]
["MSTRG.13679","POM121","ENST00000434423;ENST00000395270;ENST00000627934;ENST00000358357","GO:0006810(transport);GO:0051028(mRNA transport);GO:0005634(nucleus);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0015031(protein transport);GO:0005654(nucleoplasm);GO:0031965(nuclear membrane);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005515(protein binding);GO:0005643(nuclear pore);GO:0075733(intracellular transport of virus);GO:0043657(host cell);GO:0008139(nuclear localization sequence binding);GO:0016032(viral process);GO:0006406(mRNA export from nucleus);GO:0016925(protein sumoylation);GO:0006606(protein import into nucleus);GO:0060964(regulation of gene silencing by miRNA);GO:0006110(regulation of glycolytic process);GO:0006409(tRNA export from nucleus);GO:0007077(mitotic nuclear envelope disassembly);GO:0019083(viral transcription);GO:1900034(regulation of cellular response to heat);GO:0017056(structural constituent of nuclear pore);GO:0006405(RNA export from nucleus);GO:0005635(nuclear envelope);GO:0005487(nucleocytoplasmic transporter activity);GO:0005487(nucleocytoplasmic transporter activity)","03013(RNA transport);03013(RNA transport)","K14316","NA","POM121 transmembrane nucleoporin [Source:HGNC Symbol;Acc:HGNC:19702]",{"v":4.07886177255141,"d":"4.08"},{"v":0.948349537263287,"d":"0.95"},{"v":4.30101097989887,"d":"4.30"},{"v":2.10467581429243,"d":"2.10"},{"v":0.00669978143596449,"d":"0.01"},{"v":0.21960284032754,"d":"0.22"},"up","yes"]
["MSTRG.5493","AL031714.1","ENST00000567829;ENST00000568106","NA","NA","NA","NA",null,{"v":0.826562083314769,"d":"0.83"},{"v":0.182736450434395,"d":"0.18"},{"v":4.5232469020269,"d":"4.52"},{"v":2.17735874781719,"d":"2.18"},{"v":0.00671308088489422,"d":"0.01"},{"v":0.21960284032754,"d":"0.22"},"up","yes"]
["MSTRG.4715","AL049840.1","ENST00000498989","NA","NA","NA","NA",null,{"v":2.648721,"d":"2.65"},{"v":0.580019,"d":"0.58"},{"v":4.56661074895822,"d":"4.57"},{"v":2.19112382179845,"d":"2.19"},{"v":0.00671308088489422,"d":"0.01"},{"v":0.21960284032754,"d":"0.22"},"up","yes"]
["MSTRG.206","UBR4;AL137127.1","ENST00000375254;ENST00000375225;ENST00000459947;ENST00000425413;ENST00000375224;ENST00000417040;ENST00000492606;ENST00000465036;ENST00000466969;ENST00000494503;ENST00000483922;ENST00000419533;ENST00000375218;ENST00000475973;ENST00000486515;ENST00000497018;ENST00000606379","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0016740(transferase activity);GO:0016567(protein ubiquitination);GO:0005813(centrosome);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0005886(plasma membrane);GO:0005516(calmodulin binding);GO:0016032(viral process);GO:0042787(protein ubiquitination involved in ubiquitin-dependent protein catabolic process);GO:0043312(neutrophil degranulation);GO:0035579(specific granule membrane);GO:0070821(tertiary granule membrane);GO:0004842(ubiquitin-protein transferase activity);GO:0101003(ficolin-1-rich granule membrane);GO:0101003(ficolin-1-rich granule membrane)","05203(Viral carcinogenesis);05165(Human papillomavirus infection);05165(Human papillomavirus infection)","K10691","EC:2.3.2.27","ubiquitin protein ligase E3 component n-recognin 4 [Source:HGNC Symbol;Acc:HGNC:30313]",{"v":6.67651069302174,"d":"6.68"},{"v":1.5625015240916,"d":"1.56"},{"v":4.27296267560654,"d":"4.27"},{"v":2.09523671511111,"d":"2.10"},{"v":6.79835962170752E-3,"d":"0.01"},{"v":0.221767837884521,"d":"0.22"},"up","yes"]
["MSTRG.9434","RNF25","ENST00000295704;ENST00000463188;ENST00000474339;ENST00000473034;ENST00000423170","GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0016740(transferase activity);GO:0016567(protein ubiquitination);GO:0005829(cytosol);GO:0061630(ubiquitin protein ligase activity);GO:0051092(positive regulation of NF-kappaB transcription factor activity);GO:0004842(ubiquitin-protein transferase activity);GO:0051059(NF-kappaB binding);GO:0051059(NF-kappaB binding)","NA","NA","NA","ring finger protein 25 [Source:HGNC Symbol;Acc:HGNC:14662]",{"v":1.86243045329316,"d":"1.86"},{"v":5.5319396913474,"d":"5.53"},{"v":0.33666861122984,"d":"0.34"},{"v":-1.57059887486227,"d":"-1.57"},{"v":0.00686542721856088,"d":"0.01"},{"v":0.223328308933186,"d":"0.22"},"down","yes"]
["ENSG00000085365","SCAMP1","ENST00000621999;ENST00000510030;ENST00000320280;ENST00000511551;ENST00000614488","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0015031(protein transport);GO:0005794(Golgi apparatus);GO:0005515(protein binding);GO:0005886(plasma membrane);GO:0005768(endosome);GO:0005802(trans-Golgi network);GO:0055038(recycling endosome membrane);GO:0043312(neutrophil degranulation);GO:0035579(specific granule membrane);GO:0006892(post-Golgi vesicle-mediated transport);GO:0006887(exocytosis);GO:0030136(clathrin-coated vesicle);GO:0030672(synaptic vesicle membrane);GO:0042589(zymogen granule membrane);GO:0045202(synapse);GO:0045202(synapse)","NA","NA","NA","secretory carrier membrane protein 1 [Source:HGNC Symbol;Acc:HGNC:10563]",{"v":0.805834828632981,"d":"0.81"},{"v":2.40398240364277,"d":"2.40"},{"v":0.335208289133853,"d":"0.34"},{"v":-1.57687027000152,"d":"-1.58"},{"v":0.00688666052436229,"d":"0.01"},{"v":0.223393264439719,"d":"0.22"},"down","yes"]
["ENSG00000128626","MRPS12","ENST00000402029;ENST00000308018;ENST00000598734;ENST00000407800","GO:0003723(RNA binding);GO:0030529(intracellular ribonucleoprotein complex);GO:0005622(intracellular);GO:0003735(structural constituent of ribosome);GO:0006412(translation);GO:0005840(ribosome);GO:0005739(mitochondrion);GO:0015935(small ribosomal subunit);GO:0005515(protein binding);GO:0032543(mitochondrial translation);GO:0005743(mitochondrial inner membrane);GO:0070125(mitochondrial translational elongation);GO:0070126(mitochondrial translational termination);GO:0005761(mitochondrial ribosome);GO:0005763(mitochondrial small ribosomal subunit);GO:0005763(mitochondrial small ribosomal subunit)","03010(Ribosome);03010(Ribosome)","K02950","NA","mitochondrial ribosomal protein S12 [Source:HGNC Symbol;Acc:HGNC:10380]",{"v":4.46949645009328,"d":"4.47"},{"v":1.02867885447761,"d":"1.03"},{"v":4.34488998256215,"d":"4.34"},{"v":2.11931964686212,"d":"2.12"},{"v":0.00693052303375824,"d":"0.01"},{"v":0.223568908767033,"d":"0.22"},"up","yes"]
["MSTRG.3680","CMKLR1","ENST00000312143;ENST00000412676;MSTRG.3680.1;ENST00000550402;ENST00000549466;ENST00000550573","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0004930(G-protein coupled receptor activity);GO:0007186(G-protein coupled receptor signaling pathway);GO:0005886(plasma membrane);GO:0004871(signal transducer activity);GO:0007165(signal transduction);GO:0070098(chemokine-mediated signaling pathway);GO:0006935(chemotaxis);GO:0005515(protein binding);GO:0032088(negative regulation of NF-kappaB transcription factor activity);GO:0005887(integral component of plasma membrane);GO:0006955(immune response);GO:0004872(receptor activity);GO:0001501(skeletal system development);GO:0004950(chemokine receptor activity);GO:0045600(positive regulation of fat cell differentiation);GO:0050848(regulation of calcium-mediated signaling);GO:0032695(negative regulation of interleukin-12 production);GO:0010759(positive regulation of macrophage chemotaxis);GO:0010759(positive regulation of macrophage chemotaxis)","NA","NA","NA","chemerin chemokine-like receptor 1 [Source:HGNC Symbol;Acc:HGNC:2121]",{"v":0.556793862997257,"d":"0.56"},{"v":1.67775532664609,"d":"1.68"},{"v":0.331868332738549,"d":"0.33"},{"v":-1.59131712253864,"d":"-1.59"},{"v":0.00694214956382942,"d":"0.01"},{"v":0.223568908767033,"d":"0.22"},"down","yes"]
["MSTRG.8445","ZNF865","ENST00000568956;MSTRG.8445.1","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding)","NA","NA","NA","zinc finger protein 865 [Source:HGNC Symbol;Acc:HGNC:38705]",{"v":3.63032299075876,"d":"3.63"},{"v":0.839693859922179,"d":"0.84"},{"v":4.32338875396232,"d":"4.32"},{"v":2.11216256748461,"d":"2.11"},{"v":0.00694983002367167,"d":"0.01"},{"v":0.223568908767033,"d":"0.22"},"up","yes"]
["ENSG00000109756","RAPGEF2","ENST00000264431;ENST00000505478;ENST00000510253;ENST00000502485;ENST00000514565;ENST00000511336;ENST00000510510;ENST00000513816;ENST00000503328;ENST00000504604;ENST00000512056;ENST00000505026;ENST00000509891","GO:0005096(GTPase activator activity);GO:0043547(positive regulation of GTPase activity);GO:0042127(regulation of cell proliferation);GO:0017034(Rap guanyl-nucleotide exchange factor activity);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0007264(small GTPase mediated signal transduction);GO:0007165(signal transduction);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0004871(signal transducer activity);GO:0007186(G-protein coupled receptor signaling pathway);GO:0030552(cAMP binding);GO:0007275(multicellular organism development);GO:0048471(perinuclear region of cytoplasm);GO:0030054(cell junction);GO:0045202(synapse);GO:0007399(nervous system development);GO:0030154(cell differentiation);GO:0007218(neuropeptide signaling pathway);GO:0005509(calcium ion binding);GO:0005085(guanyl-nucleotide exchange factor activity);GO:0005887(integral component of plasma membrane);GO:0005923(bicellular tight junction);GO:0005768(endosome);GO:2001224(positive regulation of neuron migration);GO:0008285(negative regulation of cell proliferation);GO:0000165(MAPK cascade);GO:0043234(protein complex);GO:0005770(late endosome);GO:0043005(neuron projection);GO:0016324(apical plasma membrane);GO:0070374(positive regulation of ERK1 and ERK2 cascade);GO:2000670(positive regulation of dendritic cell apoptotic process);GO:0032092(positive regulation of protein binding);GO:0019933(cAMP-mediated signaling);GO:0061028(establishment of endothelial barrier);GO:0071321(cellular response to cGMP);GO:0005088(Ras guanyl-nucleotide exchange factor activity);GO:0005911(cell-cell junction);GO:0035556(intracellular signal transduction);GO:0048167(regulation of synaptic plasticity);GO:0030165(PDZ domain binding);GO:0043950(positive regulation of cAMP-mediated signaling);GO:0031175(neuron projection development);GO:0030033(microvillus assembly);GO:0045860(positive regulation of protein kinase activity);GO:0030139(endocytic vesicle);GO:0071320(cellular response to cAMP);GO:0001568(blood vessel development);GO:0010976(positive regulation of neuron projection development);GO:0001764(neuron migration);GO:0043025(neuronal cell body);GO:0070300(phosphatidic acid binding);GO:0071880(adenylate cyclase-activating adrenergic receptor signaling pathway);GO:0072659(protein localization to plasma membrane);GO:0019992(diacylglycerol binding);GO:0032486(Rap protein signal transduction);GO:0038180(nerve growth factor signaling pathway);GO:1990090(cellular response to nerve growth factor stimulus);GO:2001214(positive regulation of vasculogenesis);GO:0090557(establishment of endothelial intestinal barrier);GO:1901888(regulation of cell junction assembly);GO:0050699(WW domain binding);GO:0050774(negative regulation of dendrite morphogenesis);GO:2000481(positive regulation of cAMP-dependent protein kinase activity);GO:0031547(brain-derived neurotrophic factor receptor signaling pathway);GO:0031697(beta-1 adrenergic receptor binding);GO:0021591(ventricular system development);GO:0021884(forebrain neuron development);GO:0048022(negative regulation of melanin biosynthetic process);GO:0005622(intracellular);GO:0005622(intracellular)","04015(Rap1 signaling pathway);04010(MAPK signaling pathway);04530(Tight junction);04530(Tight junction)","K08018","NA","Rap guanine nucleotide exchange factor 2 [Source:HGNC Symbol;Acc:HGNC:16854]",{"v":5.33147157659309,"d":"5.33"},{"v":1.25259878034152,"d":"1.25"},{"v":4.25632825152478,"d":"4.26"},{"v":2.08960941695413,"d":"2.09"},{"v":0.00705986010018322,"d":"0.01"},{"v":0.226107706089042,"d":"0.23"},"up","yes"]
["MSTRG.4132","PNP","ENST00000361505;ENST00000554056;ENST00000554065;ENST00000553591;ENST00000553418;ENST00000556754;ENST00000556293;ENST00000557229","GO:0009116(nucleoside metabolic process);GO:0006139(nucleobase-containing compound metabolic process);GO:0003824(catalytic activity);GO:0004731(purine-nucleoside phosphorylase activity);GO:0005737(cytoplasm);GO:0016740(transferase activity);GO:0016757(transferase activity, transferring glycosyl groups);GO:0005856(cytoskeleton);GO:0006955(immune response);GO:0005576(extracellular region);GO:0016763(transferase activity, transferring pentosyl groups);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0005622(intracellular);GO:0043312(neutrophil degranulation);GO:0034774(secretory granule lumen);GO:1904813(ficolin-1-rich granule lumen);GO:0008144(drug binding);GO:0006195(purine nucleotide catabolic process);GO:0001882(nucleoside binding);GO:0042493(response to drug);GO:0042301(phosphate ion binding);GO:0002060(purine nucleobase binding);GO:0006148(inosine catabolic process);GO:0006738(nicotinamide riboside catabolic process);GO:0034356(NAD biosynthesis via nicotinamide riboside salvage pathway);GO:0034418(urate biosynthetic process);GO:0042102(positive regulation of T cell proliferation);GO:0042278(purine nucleoside metabolic process);GO:0043101(purine-containing compound salvage);GO:0046638(positive regulation of alpha-beta T cell differentiation);GO:0070970(interleukin-2 secretion);GO:0005634(nucleus);GO:0005634(nucleus)","00230(Purine metabolism);00240(Pyrimidine metabolism);00760(Nicotinate and nicotinamide metabolism);00760(Nicotinate and nicotinamide metabolism)","K03783","EC:2.4.2.1","purine nucleoside phosphorylase [Source:HGNC Symbol;Acc:HGNC:7892]",{"v":5.37737350785214,"d":"5.38"},{"v":15.7561896921962,"d":"15.76"},{"v":0.3412864158722,"d":"0.34"},{"v":-1.5509451024952,"d":"-1.55"},{"v":0.00706769114874039,"d":"0.01"},{"v":0.226107706089042,"d":"0.23"},"down","yes"]
["MSTRG.431","MTF1","ENST00000373036;ENST00000468190","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0005654(nucleoplasm);GO:0006366(transcription from RNA polymerase II promoter);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:0001047(core promoter binding);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0003713(transcription coactivator activity);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0001077(transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0010038(response to metal ion);GO:0000979(RNA polymerase II core promoter sequence-specific DNA binding);GO:0035035(histone acetyltransferase binding);GO:0006979(response to oxidative stress);GO:0045893(positive regulation of transcription, DNA-templated);GO:0046686(response to cadmium ion);GO:0046686(response to cadmium ion)","NA","NA","NA","metal regulatory transcription factor 1 [Source:HGNC Symbol;Acc:HGNC:7428]",{"v":6.02419853414756,"d":"6.02"},{"v":1.41891267397807,"d":"1.42"},{"v":4.24564431950424,"d":"4.25"},{"v":2.08598351397034,"d":"2.09"},{"v":7.14432431803358E-3,"d":"0.01"},{"v":0.227931423915725,"d":"0.23"},"up","yes"]
["ENSG00000116127","ALMS1","ENST00000484298;ENST00000490821;ENST00000614410;ENST00000613296;ENST00000620466","GO:0005829(cytosol);GO:0016197(endosomal transport);GO:0051492(regulation of stress fiber assembly);GO:0051393(alpha-actinin binding);GO:0001736(establishment of planar polarity);GO:0006629(lipid metabolic process);GO:0007286(spermatid development);GO:0007605(sensory perception of sound);GO:0019722(calcium-mediated signaling);GO:0030728(ovulation);GO:0040015(negative regulation of multicellular organism growth);GO:0042593(glucose homeostasis);GO:0042632(cholesterol homeostasis);GO:0043066(negative regulation of apoptotic process);GO:0045444(fat cell differentiation);GO:0045598(regulation of fat cell differentiation);GO:0046548(retinal rod cell development);GO:0050673(epithelial cell proliferation);GO:0060122(inner ear receptor stereocilium organization);GO:0060271(cilium assembly);GO:0005814(centriole);GO:0036064(ciliary basal body);GO:0005622(intracellular);GO:0005622(intracellular)","NA","NA","NA","ALMS1, centrosome and basal body associated protein [Source:HGNC Symbol;Acc:HGNC:428]",{"v":1.61274046783834,"d":"1.61"},{"v":0.376489941653622,"d":"0.38"},{"v":4.28362165734056,"d":"4.28"},{"v":2.09883106244516,"d":"2.10"},{"v":0.0071787109939899,"d":"0.01"},{"v":0.228401015816999,"d":"0.23"},"up","yes"]
["ENSG00000169964","TMEM42","ENST00000477126;ENST00000302392","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016021(integral component of membrane)","NA","NA","NA","transmembrane protein 42 [Source:HGNC Symbol;Acc:HGNC:28444]",{"v":0.688435136831938,"d":"0.69"},{"v":2.06590479233741,"d":"2.07"},{"v":0.333236623190669,"d":"0.33"},{"v":-1.58538113118249,"d":"-1.59"},{"v":0.00723966831543485,"d":"0.01"},{"v":0.229203828961887,"d":"0.23"},"down","yes"]
["ENSG00000169246","NPIPB3","ENST00000542817;ENST00000419180;ENST00000448012;ENST00000519305;ENST00000504841;ENST00000535190;ENST00000534903;ENST00000543368;ENST00000542953;ENST00000537983;ENST00000521589","GO:0005654(nucleoplasm);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0003674(molecular_function);GO:0008150(biological_process);GO:0005575(cellular_component);GO:0005575(cellular_component)","NA","NA","NA","nuclear pore complex interacting protein family member B3 [Source:HGNC Symbol;Acc:HGNC:28989]",{"v":1.81716045516218,"d":"1.82"},{"v":0.405308992792029,"d":"0.41"},{"v":4.48339535386178,"d":"4.48"},{"v":2.16459172444028,"d":"2.16"},{"v":0.00724341731068737,"d":"0.01"},{"v":0.229203828961887,"d":"0.23"},"up","yes"]
["MSTRG.4653","BCL11B","ENST00000357195;ENST00000345514;MSTRG.4653.1","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006366(transcription from RNA polymerase II promoter);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0005515(protein binding);GO:0007165(signal transduction);GO:0001077(transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:0043565(sequence-specific DNA binding);GO:0003334(keratinocyte development);GO:0003382(epithelial cell morphogenesis);GO:0007409(axonogenesis);GO:0008285(negative regulation of cell proliferation);GO:0009791(post-embryonic development);GO:0010468(regulation of gene expression);GO:0010837(regulation of keratinocyte proliferation);GO:0019216(regulation of lipid metabolic process);GO:0021773(striatal medium spiny neuron differentiation);GO:0021902(commitment of neuronal cell to specific neuron type in forebrain);GO:0021953(central nervous system neuron differentiation);GO:0031077(post-embryonic camera-type eye development);GO:0033077(T cell differentiation in thymus);GO:0033153(T cell receptor V(D)J recombination);GO:0042475(odontogenesis of dentin-containing tooth);GO:0043066(negative regulation of apoptotic process);GO:0043368(positive T cell selection);GO:0043588(skin development);GO:0045664(regulation of neuron differentiation);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0046632(alpha-beta T cell differentiation);GO:0048538(thymus development);GO:0071678(olfactory bulb axon guidance);GO:0005622(intracellular);GO:0043005(neuron projection);GO:0044212(transcription regulatory region DNA binding);GO:0022008(neurogenesis);GO:0035701(hematopoietic stem cell migration);GO:0097535(lymphoid lineage cell migration into thymus);GO:0097535(lymphoid lineage cell migration into thymus)","05202(Transcriptional misregulation in cancers);05202(Transcriptional misregulation in cancers)","K22046","NA","B-cell CLL/lymphoma 11B [Source:HGNC Symbol;Acc:HGNC:13222]",{"v":8.29559186662701,"d":"8.30"},{"v":1.96071156121356,"d":"1.96"},{"v":4.23090883469497,"d":"4.23"},{"v":2.08096759962703,"d":"2.08"},{"v":0.00727948988666645,"d":"0.01"},{"v":0.229719337102873,"d":"0.23"},"up","yes"]
["MSTRG.6624","SSH2","MSTRG.6624.1;ENST00000540801;ENST00000269033;MSTRG.6624.2;ENST00000577991;ENST00000590153;ENST00000582084;ENST00000579040;ENST00000579954;ENST00000324677;ENST00000578411;ENST00000577483;ENST00000394848","GO:0005737(cytoplasm);GO:0016787(hydrolase activity);GO:0003779(actin binding);GO:0004725(protein tyrosine phosphatase activity);GO:0008138(protein tyrosine/serine/threonine phosphatase activity);GO:0016791(phosphatase activity);GO:0006470(protein dephosphorylation);GO:0016311(dephosphorylation);GO:0035335(peptidyl-tyrosine dephosphorylation);GO:0004721(phosphoprotein phosphatase activity);GO:0005856(cytoskeleton);GO:0005615(extracellular space);GO:0030036(actin cytoskeleton organization);GO:0050770(regulation of axonogenesis);GO:0010591(regulation of lamellipodium assembly);GO:0008064(regulation of actin polymerization or depolymerization);GO:0030335(positive regulation of cell migration);GO:0030335(positive regulation of cell migration)","04810(Regulation of actin cytoskeleton);04360(Axon guidance);04360(Axon guidance)","K05766","EC:3.1.3.16;EC:3.1.3.48","slingshot protein phosphatase 2 [Source:HGNC Symbol;Acc:HGNC:30580]",{"v":33.507817265731,"d":"33.51"},{"v":7.94251710156127,"d":"7.94"},{"v":4.21879069786886,"d":"4.22"},{"v":2.07682951452173,"d":"2.08"},{"v":0.00731056934519774,"d":"0.01"},{"v":0.229752339466868,"d":"0.23"},"up","yes"]
["ENSG00000130940","CASZ1","ENST00000377022;ENST00000490176;ENST00000492173;ENST00000496432;ENST00000447850;ENST00000344008","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0043231(intracellular membrane-bounded organelle);GO:0046872(metal ion binding);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0007275(multicellular organism development);GO:0045893(positive regulation of transcription, DNA-templated);GO:0045664(regulation of neuron differentiation);GO:0045664(regulation of neuron differentiation)","NA","NA","NA","castor zinc finger 1 [Source:HGNC Symbol;Acc:HGNC:26002]",{"v":0.670190437191249,"d":"0.67"},{"v":0.153806936132675,"d":"0.15"},{"v":4.35734859586006,"d":"4.36"},{"v":2.12345053611305,"d":"2.12"},{"v":0.00732010381492646,"d":"0.01"},{"v":0.229752339466868,"d":"0.23"},"up","yes"]
["ENSG00000181409","AATK","ENST00000326724;ENST00000576053;ENST00000575363;ENST00000374792;ENST00000572798;ENST00000417379","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0048471(perinuclear region of cytoplasm);GO:0048471(perinuclear region of cytoplasm)","NA","NA","NA","apoptosis associated tyrosine kinase [Source:HGNC Symbol;Acc:HGNC:21]",{"v":7.17459672803213,"d":"7.17"},{"v":1.69469032433735,"d":"1.69"},{"v":4.23357390137783,"d":"4.23"},{"v":2.08187607300548,"d":"2.08"},{"v":0.00740470553861776,"d":"0.01"},{"v":0.231781254501262,"d":"0.23"},"up","yes"]
["MSTRG.8401","TFPT","ENST00000391759;ENST00000391758;ENST00000420715","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005654(nucleoplasm);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0031965(nuclear membrane);GO:0003677(DNA binding);GO:0006915(apoptotic process);GO:0005515(protein binding);GO:0006281(DNA repair);GO:0006310(DNA recombination);GO:0006974(cellular response to DNA damage stimulus);GO:0016579(protein deubiquitination);GO:0097190(apoptotic signaling pathway);GO:0031011(Ino80 complex);GO:0031011(Ino80 complex)","NA","NA","NA","TCF3 fusion partner [Source:HGNC Symbol;Acc:HGNC:13630]",{"v":2.13432001129032,"d":"2.13"},{"v":6.34647115080645,"d":"6.35"},{"v":0.336300277835362,"d":"0.34"},{"v":-1.57217812413606,"d":"-1.57"},{"v":0.00744328358388318,"d":"0.01"},{"v":0.232362506074289,"d":"0.23"},"down","yes"]
["MSTRG.15089","NACC2","MSTRG.15089.1;ENST00000371753;ENST00000467669","GO:0008285(negative regulation of cell proliferation);GO:0005634(nucleus);GO:0005730(nucleolus);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0016575(histone deacetylation);GO:0005739(mitochondrion);GO:0005515(protein binding);GO:0008284(positive regulation of cell proliferation);GO:0042803(protein homodimerization activity);GO:0045892(negative regulation of transcription, DNA-templated);GO:0000790(nuclear chromatin);GO:0001078(transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0034629(cellular protein complex localization);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:0042826(histone deacetylase binding);GO:0051260(protein homooligomerization);GO:0016604(nuclear body);GO:0016581(NuRD complex);GO:0001076(transcription factor activity, RNA polymerase II transcription factor binding);GO:0004407(histone deacetylase activity);GO:0010608(posttranscriptional regulation of gene expression);GO:1900477(negative regulation of G1/S transition of mitotic cell cycle by negative regulation of transcription from RNA polymerase II promoter);GO:1902231(positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage);GO:1902231(positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage)","NA","NA","NA","NACC family member 2 [Source:HGNC Symbol;Acc:HGNC:23846]",{"v":8.31651727925966,"d":"8.32"},{"v":1.97573901878062,"d":"1.98"},{"v":4.20931975337128,"d":"4.21"},{"v":2.07358710556432,"d":"2.07"},{"v":0.00748764986304529,"d":"0.01"},{"v":0.233120852170362,"d":"0.23"},"up","yes"]
["ENSG00000054654","SYNE2","ENST00000554805;ENST00000358025;ENST00000557307;ENST00000555002;ENST00000554928;ENST00000556342;ENST00000557005;ENST00000555323;ENST00000441438;ENST00000639659;ENST00000357395;ENST00000553289;ENST00000554997;ENST00000556725;ENST00000553455;ENST00000344113;ENST00000553308;ENST00000555612;ENST00000557084;ENST00000458046;ENST00000394768;ENST00000557060;ENST00000557024","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0031965(nuclear membrane);GO:0051015(actin filament binding);GO:0003779(actin binding);GO:0005739(mitochondrion);GO:0045111(intermediate filament cytoskeleton);GO:0005886(plasma membrane);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0016235(aggresome);GO:0034993(LINC complex);GO:0030054(cell junction);GO:0005654(nucleoplasm);GO:0005925(focal adhesion);GO:0090286(cytoskeletal anchoring at nuclear membrane);GO:0005635(nuclear envelope);GO:0070062(extracellular exosome);GO:0016529(sarcoplasmic reticulum);GO:0030335(positive regulation of cell migration);GO:0033017(sarcoplasmic reticulum membrane);GO:0030018(Z disc);GO:0031527(filopodium membrane);GO:0031258(lamellipodium membrane);GO:0051642(centrosome localization);GO:0005640(nuclear outer membrane);GO:0031981(nuclear lumen);GO:0007097(nuclear migration);GO:0031022(nuclear migration along microfilament);GO:0006998(nuclear envelope organization);GO:0007163(establishment or maintenance of cell polarity);GO:0010761(fibroblast migration);GO:0021817(nucleokinesis involved in cell motility in cerebral cortex radial glia guided migration);GO:0034504(protein localization to nucleus);GO:1902017(regulation of cilium assembly);GO:0030016(myofibril);GO:0030016(myofibril)","NA","NA","NA","spectrin repeat containing nuclear envelope protein 2 [Source:HGNC Symbol;Acc:HGNC:17084]",{"v":5.6415115633327,"d":"5.64"},{"v":1.34558508201058,"d":"1.35"},{"v":4.19260858250831,"d":"4.19"},{"v":2.06784814799182,"d":"2.07"},{"v":0.00761103700031005,"d":"0.01"},{"v":0.23632880396952,"d":"0.24"},"up","yes"]
["MSTRG.15099","SEC16A","MSTRG.15099.1;ENST00000371706;ENST00000431893;ENST00000290037;ENST00000467838;ENST00000313050;ENST00000277537;ENST00000472305;ENST00000313084","GO:0048208(COPII vesicle coating);GO:0000139(Golgi membrane);GO:0006810(transport);GO:0016020(membrane);GO:0015031(protein transport);GO:0005794(Golgi apparatus);GO:0005783(endoplasmic reticulum);GO:0005829(cytosol);GO:0005789(endoplasmic reticulum membrane);GO:0005515(protein binding);GO:0016192(vesicle-mediated transport);GO:0021762(substantia nigra development);GO:0007029(endoplasmic reticulum organization);GO:0007029(endoplasmic reticulum organization)","NA","NA","NA","SEC16 homolog A, endoplasmic reticulum export factor [Source:HGNC Symbol;Acc:HGNC:29006]",{"v":10.6075775246406,"d":"10.61"},{"v":2.53286704868617,"d":"2.53"},{"v":4.18797249154585,"d":"4.19"},{"v":2.06625196604123,"d":"2.07"},{"v":7.72379693166387E-3,"d":"0.01"},{"v":0.237658354268856,"d":"0.24"},"up","yes"]
["ENSG00000129993","CBFA2T3","ENST00000268679;ENST00000563856;ENST00000327483;ENST00000563640;ENST00000566868;ENST00000569464;ENST00000563920","GO:0005634(nucleus);GO:0016020(membrane);GO:0046872(metal ion binding);GO:0005654(nucleoplasm);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0005794(Golgi apparatus);GO:0003714(transcription corepressor activity);GO:0005515(protein binding);GO:0045892(negative regulation of transcription, DNA-templated);GO:0000139(Golgi membrane);GO:0030154(cell differentiation);GO:0005730(nucleolus);GO:0008285(negative regulation of cell proliferation);GO:0001666(response to hypoxia);GO:0008283(cell proliferation);GO:0030851(granulocyte differentiation);GO:0032436(positive regulation of proteasomal ubiquitin-dependent protein catabolic process);GO:0045820(negative regulation of glycolytic process);GO:1903715(regulation of aerobic respiration);GO:1903715(regulation of aerobic respiration)","NA","NA","NA","CBFA2/RUNX1 translocation partner 3 [Source:HGNC Symbol;Acc:HGNC:1537]",{"v":4.83950680140656,"d":"4.84"},{"v":1.1492787587073,"d":"1.15"},{"v":4.21090772342299,"d":"4.21"},{"v":2.0741312610642,"d":"2.07"},{"v":0.00773527352976634,"d":"0.01"},{"v":0.237658354268856,"d":"0.24"},"up","yes"]
["MSTRG.6261","FAM157C","ENST00000563357;ENST00000568070","NA","NA","NA","NA","family with sequence similarity 157 member C (non-protein coding) [Source:HGNC Symbol;Acc:HGNC:34081]",{"v":3.19453326408623,"d":"3.19"},{"v":0.735400394904459,"d":"0.74"},{"v":4.34393737917594,"d":"4.34"},{"v":2.11900330585786,"d":"2.12"},{"v":0.00776413632188569,"d":"0.01"},{"v":0.237658354268856,"d":"0.24"},"up","yes"]
["MSTRG.14569","ASAP1","ENST00000524124;ENST00000519483;ENST00000520342;ENST00000521057;ENST00000524367;ENST00000518721;ENST00000518957;ENST00000520625;ENST00000520189;ENST00000357668;ENST00000519169","GO:0043547(positive regulation of GTPase activity);GO:0005096(GTPase activator activity);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0046872(metal ion binding);GO:0005515(protein binding);GO:0060271(cilium assembly);GO:0005829(cytosol);GO:0045296(cadherin binding);GO:0030030(cell projection organization);GO:0001786(phosphatidylserine binding);GO:0005546(phosphatidylinositol-4,5-bisphosphate binding);GO:0005547(phosphatidylinositol-3,4,5-trisphosphate binding);GO:0061000(negative regulation of dendritic spine development);GO:0071803(positive regulation of podosome assembly);GO:1903527(positive regulation of membrane tubulation);GO:0002102(podosome);GO:0031253(cell projection membrane);GO:0043197(dendritic spine);GO:0043197(dendritic spine)","04144(Endocytosis);04666(Fc gamma R-mediated phagocytosis);04666(Fc gamma R-mediated phagocytosis)","K12488","NA","ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 [Source:HGNC Symbol;Acc:HGNC:2720]",{"v":12.4270533182367,"d":"12.43"},{"v":2.97062884710145,"d":"2.97"},{"v":4.18330729211164,"d":"4.18"},{"v":2.06464397754743,"d":"2.06"},{"v":0.00776513711891762,"d":"0.01"},{"v":0.237658354268856,"d":"0.24"},"up","yes"]
["MSTRG.4593","FOXN3;EFCAB11","ENST00000345097;ENST00000557258;MSTRG.4593.3;ENST00000553840;ENST00000555353;ENST00000557718;ENST00000555872;ENST00000261302;ENST00000555430;ENST00000555855;ENST00000557261;ENST00000553353;ENST00000538485;ENST00000556609;ENST00000554761;ENST00000556916;ENST00000615335;ENST00000554005;ENST00000555658;ENST00000557496;ENST00000556541;ENST00000557572;ENST00000316738;ENST00000555034","GO:0005634(nucleus);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0043565(sequence-specific DNA binding);GO:0005515(protein binding);GO:0007049(cell cycle);GO:0097094(craniofacial suture morphogenesis);GO:0030154(cell differentiation);GO:0008022(protein C-terminus binding);GO:0045892(negative regulation of transcription, DNA-templated);GO:0045893(positive regulation of transcription, DNA-templated);GO:0007095(mitotic G2 DNA damage checkpoint);GO:0046872(metal ion binding);GO:0005509(calcium ion binding);GO:0007095(mitotic G2 DNA damage checkpoint)","NA","NA","NA","forkhead box N3 [Source:HGNC Symbol;Acc:HGNC:1928];EF-hand calcium binding domain 11 [Source:HGNC Symbol;Acc:HGNC:20357]",{"v":3.81617116415826,"d":"3.82"},{"v":0.90969770964572,"d":"0.91"},{"v":4.19498820728532,"d":"4.19"},{"v":2.06866675504772,"d":"2.07"},{"v":7.76874756435008E-3,"d":"0.01"},{"v":0.237658354268856,"d":"0.24"},"up","yes"]
["MSTRG.4845","IGHV5-51","ENST00000390626","GO:0016020(membrane);GO:0005886(plasma membrane);GO:0005576(extracellular region);GO:0002376(immune system process);GO:0003823(antigen binding);GO:0002250(adaptive immune response);GO:0034987(immunoglobulin receptor binding);GO:0006910(phagocytosis, recognition);GO:0006911(phagocytosis, engulfment);GO:0006958(complement activation, classical pathway);GO:0042742(defense response to bacterium);GO:0045087(innate immune response);GO:0050853(B cell receptor signaling pathway);GO:0050871(positive regulation of B cell activation);GO:0009897(external side of plasma membrane);GO:0042571(immunoglobulin complex, circulating);GO:0072562(blood microparticle)","NA","NA","NA","immunoglobulin heavy variable 5-51 [Source:HGNC Symbol;Acc:HGNC:5659]",{"v":1.995746,"d":"2.00"},{"v":6.165196,"d":"6.17"},{"v":0.323711687349437,"d":"0.32"},{"v":-1.62721864105888,"d":"-1.63"},{"v":0.00777695300539378,"d":"0.01"},{"v":0.237658354268856,"d":"0.24"},"down","yes"]
["MSTRG.2886","AP000892.3","ENST00000624094","NA","NA","NA","NA",null,{"v":0.672478,"d":"0.67"},{"v":0.149547,"d":"0.15"},{"v":4.49676690271286,"d":"4.50"},{"v":2.16888810148167,"d":"2.17"},{"v":0.00779710953039129,"d":"0.01"},{"v":0.237658354268856,"d":"0.24"},"up","yes"]
["MSTRG.6006","TPPP3","ENST00000393957;ENST00000561537;ENST00000562206;ENST00000564104","GO:0005737(cytoplasm);GO:0005856(cytoskeleton);GO:0048471(perinuclear region of cytoplasm);GO:0015631(tubulin binding);GO:0001578(microtubule bundle formation);GO:0005874(microtubule);GO:0046785(microtubule polymerization);GO:0070062(extracellular exosome);GO:0097427(microtubule bundle);GO:0097427(microtubule bundle)","NA","NA","NA","tubulin polymerization promoting protein family member 3 [Source:HGNC Symbol;Acc:HGNC:24162]",{"v":1.12537780901452,"d":"1.13"},{"v":3.30109911344538,"d":"3.30"},{"v":0.340910033397923,"d":"0.34"},{"v":-1.55253703451066,"d":"-1.55"},{"v":0.00782739588013052,"d":"0.01"},{"v":0.237956932868994,"d":"0.24"},"down","yes"]
["MSTRG.4399","STYX","ENST00000354586;ENST00000556861;ENST00000442123","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005654(nucleoplasm);GO:0016787(hydrolase activity);GO:0008138(protein tyrosine/serine/threonine phosphatase activity);GO:0016791(phosphatase activity);GO:0006470(protein dephosphorylation);GO:0016311(dephosphorylation);GO:0005829(cytosol);GO:0004721(phosphoprotein phosphatase activity);GO:0005515(protein binding);GO:0070372(regulation of ERK1 and ERK2 cascade);GO:0007283(spermatogenesis);GO:0045204(MAPK export from nucleus);GO:0045204(MAPK export from nucleus)","NA","NA","NA","serine/threonine/tyrosine interacting protein [Source:HGNC Symbol;Acc:HGNC:11447]",{"v":1.79710282322218,"d":"1.80"},{"v":5.18819473583769,"d":"5.19"},{"v":0.346383070552192,"d":"0.35"},{"v":-1.52955967471663,"d":"-1.53"},{"v":0.00788032181134849,"d":"0.01"},{"v":0.238819792133544,"d":"0.24"},"down","yes"]
["ENSG00000105738","SIPA1L3","ENST00000222345;ENST00000595982;ENST00000595384;ENST00000601222;ENST00000601054;ENST00000599644;ENST00000601881;ENST00000595495;ENST00000596403;ENST00000594553","GO:0016020(membrane);GO:0005886(plasma membrane);GO:0043547(positive regulation of GTPase activity);GO:0005096(GTPase activator activity);GO:0005615(extracellular space);GO:0051056(regulation of small GTPase mediated signal transduction);GO:0001654(eye development);GO:0001725(stress fiber);GO:0007010(cytoskeleton organization);GO:0016324(apical plasma membrane);GO:0003382(epithelial cell morphogenesis);GO:0002244(hematopoietic progenitor cell differentiation);GO:0090162(establishment of epithelial cell polarity);GO:0045177(apical part of cell);GO:0061689(tricellular tight junction);GO:0061689(tricellular tight junction)","04015(Rap1 signaling pathway);04015(Rap1 signaling pathway)","K17703","NA","signal induced proliferation associated 1 like 3 [Source:HGNC Symbol;Acc:HGNC:23801]",{"v":2.52757452578616,"d":"2.53"},{"v":0.600564557910015,"d":"0.60"},{"v":4.20866415191433,"d":"4.21"},{"v":2.07336238834383,"d":"2.07"},{"v":0.00791115269067284,"d":"0.01"},{"v":0.238819792133544,"d":"0.24"},"up","yes"]
["ENSG00000184271","POU6F1","ENST00000636728;ENST00000547854;ENST00000333640;ENST00000636119;ENST00000636068;ENST00000389243","GO:0005634(nucleus);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0000977(RNA polymerase II regulatory region sequence-specific DNA binding);GO:0015629(actin cytoskeleton);GO:0016604(nuclear body);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0043565(sequence-specific DNA binding);GO:0007420(brain development);GO:0007517(muscle organ development);GO:0001227(transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding);GO:0007507(heart development);GO:0007507(heart development)","NA","NA","NA","POU class 6 homeobox 1 [Source:HGNC Symbol;Acc:HGNC:9224]",{"v":0.900995146329365,"d":"0.90"},{"v":0.204862438822751,"d":"0.20"},{"v":4.39804949851698,"d":"4.40"},{"v":2.13686384131501,"d":"2.14"},{"v":0.00791747351859248,"d":"0.01"},{"v":0.238819792133544,"d":"0.24"},"up","yes"]
["ENSG00000155034","FBXL18","ENST00000382368;ENST00000415009;ENST00000458142","GO:0005829(cytosol);GO:0000209(protein polyubiquitination);GO:0031146(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process);GO:0043687(post-translational protein modification);GO:0004842(ubiquitin-protein transferase activity);GO:0005515(protein binding);GO:0005515(protein binding)","NA","NA","NA","F-box and leucine rich repeat protein 18 [Source:HGNC Symbol;Acc:HGNC:21874]",{"v":0.891359152515723,"d":"0.89"},{"v":0.205543365959119,"d":"0.21"},{"v":4.33659898657594,"d":"4.34"},{"v":2.11656404065854,"d":"2.12"},{"v":0.00797706001684477,"d":"0.01"},{"v":0.239937674739722,"d":"0.24"},"up","yes"]
["ENSG00000237440","ZNF737","ENST00000427401;ENST00000594419;ENST00000596797;ENST00000596530","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0005622(intracellular);GO:0005622(intracellular)","NA","NA","NA","zinc finger protein 737 [Source:HGNC Symbol;Acc:HGNC:32468]",{"v":0.37788407487991,"d":"0.38"},{"v":1.14239617434303,"d":"1.14"},{"v":0.330781985590265,"d":"0.33"},{"v":-1.59604742751018,"d":"-1.60"},{"v":0.00799585637856475,"d":"0.01"},{"v":0.239937674739722,"d":"0.24"},"down","yes"]
["MSTRG.11733","PDLIM5","ENST00000317968;ENST00000627587;ENST00000514830;ENST00000514743;ENST00000510099;ENST00000542407;ENST00000509333;ENST00000380180;ENST00000504489;ENST00000511767;ENST00000359265","GO:0061049(cell growth involved in cardiac muscle cell development);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0046872(metal ion binding);GO:0003779(actin binding);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0030054(cell junction);GO:0045202(synapse);GO:0045211(postsynaptic membrane);GO:0014069(postsynaptic density);GO:0098641(cadherin binding involved in cell-cell adhesion);GO:0098609(cell-cell adhesion);GO:0005913(cell-cell adherens junction);GO:0043005(neuron projection);GO:0061001(regulation of dendritic spine morphogenesis);GO:0005080(protein kinase C binding);GO:0051963(regulation of synapse assembly);GO:0042805(actinin binding);GO:0015629(actin cytoskeleton);GO:0047485(protein N-terminus binding);GO:0047485(protein N-terminus binding)","NA","NA","NA","PDZ and LIM domain 5 [Source:HGNC Symbol;Acc:HGNC:17468]",{"v":3.35400556771867,"d":"3.35"},{"v":0.802322011992786,"d":"0.80"},{"v":4.18037336329347,"d":"4.18"},{"v":2.06363180003748,"d":"2.06"},{"v":0.00810717844084412,"d":"0.01"},{"v":0.242651193900832,"d":"0.24"},"up","yes"]
["MSTRG.156","TARDBP;AL109811.3;AL109811.4","ENST00000240185;ENST00000607145;ENST00000614757;ENST00000638264;ENST00000618606;ENST00000621715;ENST00000496840;ENST00000614494;ENST00000476201;ENST00000622057;ENST00000619555;ENST00000480464;ENST00000617172;ENST00000472476;ENST00000616545;ENST00000439080;ENST00000629725;ENST00000622108;ENST00000613864","GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0005634(nucleus);GO:0003730(mRNA 3'-UTR binding);GO:0006397(mRNA processing);GO:0008380(RNA splicing);GO:0005654(nucleoplasm);GO:0006366(transcription from RNA polymerase II promoter);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0001205(transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding);GO:0032024(positive regulation of insulin secretion);GO:0034976(response to endoplasmic reticulum stress);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0005726(perichromatin fibrils);GO:0005737(cytoplasm);GO:0016607(nuclear speck);GO:0035061(interchromatin granule);GO:0042802(identical protein binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0003690(double-stranded DNA binding);GO:0070935(3'-UTR-mediated mRNA stabilization);GO:0010629(negative regulation of gene expression);GO:0051726(regulation of cell cycle);GO:0001933(negative regulation of protein phosphorylation);GO:0042981(regulation of apoptotic process);GO:0043922(negative regulation by host of viral transcription);GO:0071765(nuclear inner membrane organization);GO:0071765(nuclear inner membrane organization)","NA","NA","NA","TAR DNA binding protein [Source:HGNC Symbol;Acc:HGNC:11571]",{"v":7.37181146045238,"d":"7.37"},{"v":1.76953547860539,"d":"1.77"},{"v":4.16595855216323,"d":"4.17"},{"v":2.05864848582935,"d":"2.06"},{"v":0.00813860665389578,"d":"0.01"},{"v":0.242965653140596,"d":"0.24"},"up","yes"]
["ENSG00000181830","SLC35C1","ENST00000314134;ENST00000526817;ENST00000442528","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005794(Golgi apparatus);GO:0000139(Golgi membrane);GO:0008643(carbohydrate transport);GO:0005457(GDP-fucose transmembrane transporter activity);GO:0015783(GDP-fucose transport);GO:0030259(lipid glycosylation);GO:0045746(negative regulation of Notch signaling pathway);GO:0045746(negative regulation of Notch signaling pathway)","NA","NA","NA","solute carrier family 35 member C1 [Source:HGNC Symbol;Acc:HGNC:20197]",{"v":2.66304696381798,"d":"2.66"},{"v":0.628169789345172,"d":"0.63"},{"v":4.2393744637004,"d":"4.24"},{"v":2.08385140519067,"d":"2.08"},{"v":0.00819564079201297,"d":"0.01"},{"v":0.244040965429863,"d":"0.24"},"up","yes"]
["ENSG00000196233","LCOR","ENST00000371103;ENST00000356016;ENST00000371097;ENST00000540664;ENST00000469510;ENST00000493486;ENST00000421806","GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0005515(protein binding)","NA","NA","NA","ligand dependent nuclear receptor corepressor [Source:HGNC Symbol;Acc:HGNC:29503]",{"v":2.19543576348962,"d":"2.20"},{"v":0.529440175211376,"d":"0.53"},{"v":4.14671168959383,"d":"4.15"},{"v":2.0519677437829,"d":"2.05"},{"v":0.00828686205287316,"d":"0.01"},{"v":0.246089000353114,"d":"0.25"},"up","yes"]
["MSTRG.15060","EEF1A1P5","ENST00000436459","NA","NA","NA","NA","eukaryotic translation elongation factor 1 alpha 1 pseudogene 5 [Source:HGNC Symbol;Acc:HGNC:3200]",{"v":49.777355,"d":"49.78"},{"v":141.438034,"d":"141.44"},{"v":0.351937548849131,"d":"0.35"},{"v":-1.50660864886316,"d":"-1.51"},{"v":0.00832725200337889,"d":"0.01"},{"v":0.246089000353114,"d":"0.25"},"down","yes"]
["MSTRG.10885","ELP6","ENST00000296149;ENST00000460502;ENST00000412761;ENST00000442215;ENST00000485029;ENST00000444760;ENST00000461208;ENST00000414236;ENST00000445044;ENST00000483205;ENST00000425291;ENST00000439305;ENST00000494161","GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0033588(Elongator holoenzyme complex);GO:0003674(molecular_function);GO:0008150(biological_process);GO:0030335(positive regulation of cell migration);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016021(integral component of membrane)","NA","NA","NA","elongator acetyltransferase complex subunit 6 [Source:HGNC Symbol;Acc:HGNC:25976]",{"v":1.35950177543012,"d":"1.36"},{"v":3.94074671717477,"d":"3.94"},{"v":0.344985829590384,"d":"0.34"},{"v":-1.53539099096623,"d":"-1.54"},{"v":0.00837482817923114,"d":"0.01"},{"v":0.246089000353114,"d":"0.25"},"down","yes"]
["MSTRG.7335","ARHGDIA","ENST00000269321;ENST00000582984;ENST00000541078;ENST00000582309;ENST00000583111;ENST00000578351;ENST00000400721;ENST00000584397;ENST00000584461;ENST00000580685;ENST00000580033;ENST00000583791;ENST00000583868;ENST00000579121;ENST00000582520;ENST00000583499","GO:0005737(cytoplasm);GO:0050790(regulation of catalytic activity);GO:0043547(positive regulation of GTPase activity);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0005096(GTPase activator activity);GO:0005094(Rho GDP-dissociation inhibitor activity);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0051056(regulation of small GTPase mediated signal transduction);GO:0043066(negative regulation of apoptotic process);GO:0071526(semaphorin-plexin signaling pathway);GO:2000249(regulation of actin cytoskeleton reorganization);GO:0006928(movement of cell or subcellular component);GO:0050772(positive regulation of axonogenesis);GO:0035023(regulation of Rho protein signal transduction);GO:0050771(negative regulation of axonogenesis);GO:0007162(negative regulation of cell adhesion);GO:0005504(fatty acid binding);GO:0017048(Rho GTPase binding);GO:0019901(protein kinase binding);GO:0051879(Hsp90 protein binding);GO:0007266(Rho protein signal transduction);GO:0008360(regulation of cell shape);GO:0030336(negative regulation of cell migration);GO:0032880(regulation of protein localization);GO:0071260(cellular response to mechanical stimulus);GO:0071407(cellular response to organic cyclic compound);GO:0071461(cellular response to redox state);GO:0001772(immunological synapse);GO:0005615(extracellular space);GO:0005634(nucleus);GO:0016020(membrane);GO:0016020(membrane)","04962(Vasopressin-regulated water reabsorption);04722(Neurotrophin signaling pathway);04722(Neurotrophin signaling pathway)","K12462","NA","Rho GDP dissociation inhibitor alpha [Source:HGNC Symbol;Acc:HGNC:678]",{"v":39.5126408511884,"d":"39.51"},{"v":9.54585661246986,"d":"9.55"},{"v":4.13924516732973,"d":"4.14"},{"v":2.0493677018699,"d":"2.05"},{"v":0.00838023205161152,"d":"0.01"},{"v":0.246089000353114,"d":"0.25"},"up","yes"]
["MSTRG.6286","SLC43A2","MSTRG.6286.1;ENST00000301335;ENST00000576769;ENST00000572135;ENST00000572801;ENST00000571376;ENST00000574274;ENST00000576721;ENST00000571650;ENST00000576537;ENST00000574743;ENST00000575944","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0055085(transmembrane transport);GO:0003333(amino acid transmembrane transport);GO:0005886(plasma membrane);GO:0005887(integral component of plasma membrane);GO:1902475(L-alpha-amino acid transmembrane transport);GO:0006865(amino acid transport);GO:0015179(L-amino acid transmembrane transporter activity);GO:0015807(L-amino acid transport);GO:0015171(amino acid transmembrane transporter activity);GO:0015175(neutral amino acid transmembrane transporter activity);GO:0015804(neutral amino acid transport);GO:0015804(neutral amino acid transport)","NA","NA","NA","solute carrier family 43 member 2 [Source:HGNC Symbol;Acc:HGNC:23087]",{"v":11.4767106292039,"d":"11.48"},{"v":2.77845395410813,"d":"2.78"},{"v":4.1306103389746,"d":"4.13"},{"v":2.04635497001153,"d":"2.05"},{"v":0.00840695508225753,"d":"0.01"},{"v":0.246089000353114,"d":"0.25"},"up","yes"]
["ENSG00000282572","AC215522.2","ENST00000633163;ENST00000635373;ENST00000632586","NA","NA","NA","NA",null,{"v":2.35602842673522,"d":"2.36"},{"v":0.531042393316195,"d":"0.53"},{"v":4.43661081749529,"d":"4.44"},{"v":2.14945800452276,"d":"2.15"},{"v":0.00841513364858031,"d":"0.01"},{"v":0.246089000353114,"d":"0.25"},"up","yes"]
["MSTRG.12866","PRRC2A","ENST00000376033;ENST00000376007;ENST00000492691;ENST00000464890;ENST00000469501;ENST00000462617;ENST00000483470;ENST00000484787;ENST00000482441;MSTRG.12866.1;ENST00000469577;ENST00000487839;ENST00000464079;ENST00000487089;ENST00000460302","GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005515(protein binding);GO:0070062(extracellular exosome);GO:0030154(cell differentiation);GO:0030154(cell differentiation)","NA","NA","NA","proline rich coiled-coil 2A [Source:HGNC Symbol;Acc:HGNC:13918]",{"v":21.4752973385069,"d":"21.48"},{"v":5.20309266083725,"d":"5.20"},{"v":4.12741012670169,"d":"4.13"},{"v":2.04523680116557,"d":"2.05"},{"v":0.00841883876417423,"d":"0.01"},{"v":0.246089000353114,"d":"0.25"},"up","yes"]
["ENSG00000167112","TRUB2","ENST00000372890;ENST00000460320;ENST00000461180","GO:0003723(RNA binding);GO:0006396(RNA processing);GO:0016853(isomerase activity);GO:0005829(cytosol);GO:0008033(tRNA processing);GO:0009982(pseudouridine synthase activity);GO:0001522(pseudouridine synthesis);GO:0009451(RNA modification);GO:0009451(RNA modification)","NA","NA","NA","TruB pseudouridine synthase family member 2 [Source:HGNC Symbol;Acc:HGNC:17170]",{"v":0.663832416816327,"d":"0.66"},{"v":1.92055113371429,"d":"1.92"},{"v":0.345646832913266,"d":"0.35"},{"v":-1.53262938828251,"d":"-1.53"},{"v":0.00843394662365791,"d":"0.01"},{"v":0.246089000353114,"d":"0.25"},"down","yes"]
["ENSG00000063587","ZNF275","ENST00000370251;ENST00000370249;ENST00000438239","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding)","NA","NA","NA","zinc finger protein 275 [Source:HGNC Symbol;Acc:HGNC:13069]",{"v":1.45641596264897,"d":"1.46"},{"v":0.348111669738297,"d":"0.35"},{"v":4.18376081371783,"d":"4.18"},{"v":2.06480037483369,"d":"2.06"},{"v":0.00858501987492223,"d":"0.01"},{"v":0.249380192400062,"d":"0.25"},"up","yes"]
["MSTRG.224","LINC00339","ENST00000452322;ENST00000642072;ENST00000404210;ENST00000641009;ENST00000416769;ENST00000634934","NA","NA","NA","NA","long intergenic non-protein coding RNA 339 [Source:HGNC Symbol;Acc:HGNC:25011]",{"v":0.269432381774708,"d":"0.27"},{"v":0.805880314293305,"d":"0.81"},{"v":0.334332998332363,"d":"0.33"},{"v":-1.58064234034777,"d":"-1.58"},{"v":0.00860757660453769,"d":"0.01"},{"v":0.249380192400062,"d":"0.25"},"down","yes"]
["MSTRG.8078","KMT2B","ENST00000420124;ENST00000592092;ENST00000585476;ENST00000586308","GO:0005634(nucleus);GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0008168(methyltransferase activity);GO:0016740(transferase activity);GO:0032259(methylation);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0016569(covalent chromatin modification);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0005515(protein binding);GO:0018024(histone-lysine N-methyltransferase activity);GO:0005654(nucleoplasm);GO:0035097(histone methyltransferase complex);GO:0048096(chromatin-mediated maintenance of transcription);GO:0045652(regulation of megakaryocyte differentiation);GO:0051568(histone H3-K4 methylation);GO:0042800(histone methyltransferase activity (H3-K4 specific));GO:0001541(ovarian follicle development);GO:0007613(memory);GO:0009994(oocyte differentiation);GO:0016458(gene silencing);GO:0030728(ovulation);GO:0034968(histone lysine methylation);GO:0051569(regulation of histone H3-K4 methylation);GO:0080182(histone H3-K4 trimethylation);GO:0080182(histone H3-K4 trimethylation)","00310(Lysine degradation);00310(Lysine degradation)","K14959","EC:2.1.1.43","lysine methyltransferase 2B [Source:HGNC Symbol;Acc:HGNC:15840]",{"v":5.61152268625353,"d":"5.61"},{"v":1.36191231189804,"d":"1.36"},{"v":4.12032598371402,"d":"4.12"},{"v":2.04275848218597,"d":"2.04"},{"v":0.00862244548212489,"d":"0.01"},{"v":0.249380192400062,"d":"0.25"},"up","yes"]
["ENSG00000256683","ZNF350","ENST00000243644;ENST00000593596;ENST00000601430;ENST00000594929;ENST00000597788;ENST00000598254;ENST00000600703;ENST00000597555","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0005654(nucleoplasm);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0005622(intracellular);GO:0005515(protein binding);GO:0016604(nuclear body);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0045892(negative regulation of transcription, DNA-templated);GO:0016363(nuclear matrix);GO:0001227(transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding);GO:0017053(transcriptional repressor complex);GO:0001162(RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding);GO:0001162(RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding)","NA","NA","NA","zinc finger protein 350 [Source:HGNC Symbol;Acc:HGNC:16656]",{"v":0.698523479400749,"d":"0.70"},{"v":2.04517097576559,"d":"2.05"},{"v":0.341547717857312,"d":"0.34"},{"v":-1.54984094241335,"d":"-1.55"},{"v":0.00863263905492335,"d":"0.01"},{"v":0.249380192400062,"d":"0.25"},"down","yes"]
["MSTRG.4754","IGHG3;MIR8071-2","MSTRG.4754.3;MSTRG.4754.2;MSTRG.4754.1","NA","NA","NA","NA",null,{"v":4.78049841017488,"d":"4.78"},{"v":13.7649951812401,"d":"13.76"},{"v":0.347293867322967,"d":"0.35"},{"v":-1.52577115972411,"d":"-1.53"},{"v":0.0086726445410501,"d":"0.01"},{"v":0.249471333831463,"d":"0.25"},"down","yes"]
["MSTRG.9383","KLF7","MSTRG.9383.1;ENST00000309446;ENST00000426163;ENST00000458272;ENST00000451244;ENST00000457962;ENST00000421199;ENST00000467833;ENST00000423015","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006366(transcription from RNA polymerase II promoter);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0007409(axonogenesis);GO:0007411(axon guidance);GO:0045893(positive regulation of transcription, DNA-templated);GO:0048813(dendrite morphogenesis);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0003713(transcription coactivator activity);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0001077(transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0008270(zinc ion binding);GO:0008270(zinc ion binding)","NA","NA","NA","Kruppel like factor 7 [Source:HGNC Symbol;Acc:HGNC:6350]",{"v":7.99682365763334,"d":"8.00"},{"v":1.94674909857482,"d":"1.95"},{"v":4.10778341363439,"d":"4.11"},{"v":2.03836011634135,"d":"2.04"},{"v":0.00867875819064076,"d":"0.01"},{"v":0.249471333831463,"d":"0.25"},"up","yes"]
["ENSG00000126705","AHDC1","ENST00000374011;ENST00000490295;ENST00000247087;ENST00000480033;ENST00000487743","GO:0003677(DNA binding);GO:0003677(DNA binding)","NA","NA","NA","AT-hook DNA binding motif containing 1 [Source:HGNC Symbol;Acc:HGNC:25230]",{"v":1.77596710716781,"d":"1.78"},{"v":0.426293007684784,"d":"0.43"},{"v":4.16607139960649,"d":"4.17"},{"v":2.05868756500878,"d":"2.06"},{"v":0.00873814465697691,"d":"0.01"},{"v":0.25003031072378,"d":"0.25"},"up","yes"]
["MSTRG.13199","FOXO3","ENST00000406360;ENST00000343882","GO:0043065(positive regulation of apoptotic process);GO:0005737(cytoplasm);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0006355(regulation of transcription, DNA-templated);GO:0006366(transcription from RNA polymerase II promoter);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0031490(chromatin DNA binding);GO:0005829(cytosol);GO:0043565(sequence-specific DNA binding);GO:0005515(protein binding);GO:0006915(apoptotic process);GO:0045893(positive regulation of transcription, DNA-templated);GO:0001047(core promoter binding);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0019901(protein kinase binding);GO:0006417(regulation of translation);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0009653(anatomical structure morphogenesis);GO:0034599(cellular response to oxidative stress);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0033209(tumor necrosis factor-mediated signaling pathway);GO:0001227(transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding);GO:0008013(beta-catenin binding);GO:0043525(positive regulation of neuron apoptotic process);GO:0045648(positive regulation of erythrocyte differentiation);GO:0001221(transcription cofactor binding);GO:0001228(transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding);GO:0001542(ovulation from ovarian follicle);GO:0001544(initiation of primordial ovarian follicle growth);GO:0001547(antral ovarian follicle growth);GO:0001556(oocyte maturation);GO:0007568(aging);GO:0030330(DNA damage response, signal transduction by p53 class mediator);GO:0031667(response to nutrient levels);GO:0042493(response to drug);GO:0042593(glucose homeostasis);GO:0045665(negative regulation of neuron differentiation);GO:0048854(brain morphogenesis);GO:0071333(cellular response to glucose stimulus);GO:0071386(cellular response to corticosterone stimulus);GO:0071456(cellular response to hypoxia);GO:0071548(response to dexamethasone);GO:0090090(negative regulation of canonical Wnt signaling pathway);GO:0097150(neuronal stem cell population maintenance);GO:0097192(extrinsic apoptotic signaling pathway in absence of ligand);GO:1901300(positive regulation of hydrogen peroxide-mediated programmed cell death);GO:1903428(positive regulation of reactive oxygen species biosynthetic process);GO:1904646(cellular response to amyloid-beta);GO:1990090(cellular response to nerve growth factor stimulus);GO:1990785(response to water-immersion restraint stress);GO:2000177(regulation of neural precursor cell proliferation);GO:2000353(positive regulation of endothelial cell apoptotic process);GO:2000377(regulation of reactive oxygen species metabolic process);GO:0005739(mitochondrion);GO:0016020(membrane);GO:0016020(membrane)","04068(FoxO signaling pathway);04151(PI3K-Akt signaling pathway);04152(AMPK signaling pathway);04137(Mitophagy - animal);04218(Cellular senescence);04062(Chemokine signaling pathway);04917(Prolactin signaling pathway);04722(Neurotrophin signaling pathway);04211(Longevity regulating pathway - mammal);04213(Longevity regulating pathway - multiple species);05213(Endometrial cancer);05223(Non-small cell lung cancer);01521(EGFR tyrosine kinase inhibitor resistance);01521(EGFR tyrosine kinase inhibitor resistance)","K09408","NA","forkhead box O3 [Source:HGNC Symbol;Acc:HGNC:3821]",{"v":11.9204611666883,"d":"11.92"},{"v":2.90734570288823,"d":"2.91"},{"v":4.1001182469791,"d":"4.10"},{"v":2.03566551750398,"d":"2.04"},{"v":0.00874126463048779,"d":"0.01"},{"v":0.25003031072378,"d":"0.25"},"up","yes"]
["ENSG00000198064","NPIPB13","ENST00000520915;ENST00000564502;ENST00000568053;ENST00000562937;ENST00000618637;ENST00000543463;ENST00000564219","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005654(nucleoplasm);GO:0005654(nucleoplasm)","NA","NA","NA","nuclear pore complex interacting protein family, member B13 [Source:HGNC Symbol;Acc:HGNC:41989]",{"v":1.48963361072664,"d":"1.49"},{"v":0.34943720780469,"d":"0.35"},{"v":4.26295076041026,"d":"4.26"},{"v":2.09185239142144,"d":"2.09"},{"v":0.0088661491729265,"d":"0.01"},{"v":0.252979337457483,"d":"0.25"},"up","yes"]
["ENSG00000112159","MDN1","ENST00000369393;ENST00000629399;ENST00000468568","GO:0005634(nucleus);GO:0016020(membrane);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0005730(nucleolus);GO:0005829(cytosol);GO:0045111(intermediate filament cytoskeleton);GO:0005515(protein binding);GO:0016887(ATPase activity);GO:0000027(ribosomal large subunit assembly);GO:0030687(preribosome, large subunit precursor);GO:0051082(unfolded protein binding);GO:0006461(protein complex assembly);GO:0006364(rRNA processing);GO:0006364(rRNA processing)","03008(Ribosome biogenesis in eukaryotes);03008(Ribosome biogenesis in eukaryotes)","K14572","NA","midasin AAA ATPase 1 [Source:HGNC Symbol;Acc:HGNC:18302]",{"v":2.14232726583163,"d":"2.14"},{"v":0.522066257660467,"d":"0.52"},{"v":4.10355435616933,"d":"4.10"},{"v":2.03687406353413,"d":"2.04"},{"v":0.00890899011126175,"d":"0.01"},{"v":0.253085023818674,"d":"0.25"},"up","yes"]
["ENSG00000130396","AFDN","ENST00000366806;ENST00000423229;ENST00000511637;ENST00000392112;ENST00000509296;ENST00000515794;ENST00000507704;ENST00000511503;ENST00000366809;ENST00000351017;ENST00000400824;ENST00000344191;ENST00000485634;ENST00000400825;ENST00000400822","GO:0007165(signal transduction);GO:0005886(plasma membrane);GO:0005911(cell-cell junction);GO:0030054(cell junction);GO:0016607(nuclear speck);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0007155(cell adhesion);GO:0005515(protein binding);GO:0045296(cadherin binding);GO:0043547(positive regulation of GTPase activity);GO:0005912(adherens junction);GO:0032880(regulation of protein localization);GO:0007267(cell-cell signaling);GO:0005913(cell-cell adherens junction);GO:0034332(adherens junction organization);GO:0008022(protein C-terminus binding);GO:0017016(Ras GTPase binding);GO:0090557(establishment of endothelial intestinal barrier);GO:0050839(cell adhesion molecule binding);GO:0021537(telencephalon development);GO:0021987(cerebral cortex development);GO:0034334(adherens junction maintenance);GO:0048854(brain morphogenesis);GO:0048872(homeostasis of number of cells);GO:0060019(radial glial cell differentiation);GO:0060563(neuroepithelial cell differentiation);GO:0070445(regulation of oligodendrocyte progenitor proliferation);GO:1902414(protein localization to cell junction);GO:0005737(cytoplasm);GO:0043296(apical junction complex);GO:0045177(apical part of cell);GO:0045177(apical part of cell)","04014(Ras signaling pathway);04015(Rap1 signaling pathway);04024(cAMP signaling pathway);04520(Adherens junction);04530(Tight junction);04670(Leukocyte transendothelial migration);04670(Leukocyte transendothelial migration)","K05702","NA","afadin, adherens junction formation factor [Source:HGNC Symbol;Acc:HGNC:7137]",{"v":1.41217339373178,"d":"1.41"},{"v":0.341169736953353,"d":"0.34"},{"v":4.13921060625861,"d":"4.14"},{"v":2.04935565588275,"d":"2.05"},{"v":0.00891343965743888,"d":"0.01"},{"v":0.253085023818674,"d":"0.25"},"up","yes"]
["MSTRG.1284","KIF21B","ENST00000360529;ENST00000461742;ENST00000422435;ENST00000534043;ENST00000332129","GO:0005737(cytoplasm);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0003777(microtubule motor activity);GO:0005856(cytoskeleton);GO:0042995(cell projection);GO:0008017(microtubule binding);GO:0005874(microtubule);GO:0031410(cytoplasmic vesicle);GO:0007018(microtubule-based movement);GO:0030425(dendrite);GO:0030424(axon);GO:0030426(growth cone);GO:0016887(ATPase activity);GO:0005871(kinesin complex);GO:0005871(kinesin complex)","NA","NA","NA","kinesin family member 21B [Source:HGNC Symbol;Acc:HGNC:29442]",{"v":5.64220653604938,"d":"5.64"},{"v":1.37859230880658,"d":"1.38"},{"v":4.09273031628453,"d":"4.09"},{"v":2.03306360590212,"d":"2.03"},{"v":0.00893634358391513,"d":"0.01"},{"v":0.253116483024406,"d":"0.25"},"up","yes"]
["MSTRG.491","SZT2","ENST00000634258;ENST00000638263;ENST00000639852;ENST00000638769;ENST00000470139;ENST00000372450;ENST00000638642;ENST00000638631;ENST00000357658;ENST00000406439;ENST00000460536;ENST00000640484;ENST00000639197;ENST00000562955","GO:0016020(membrane);GO:0005765(lysosomal membrane);GO:0005764(lysosome);GO:0005777(peroxisome);GO:1904262(negative regulation of TORC1 signaling);GO:0003674(molecular_function);GO:0070062(extracellular exosome);GO:0061700(GATOR2 complex);GO:0042149(cellular response to glucose starvation);GO:0061462(protein localization to lysosome);GO:0034198(cellular response to amino acid starvation);GO:0007417(central nervous system development);GO:0009791(post-embryonic development);GO:1990130(GATOR1 complex);GO:0021540(corpus callosum morphogenesis);GO:1901668(regulation of superoxide dismutase activity);GO:0140007(KICSTOR complex);GO:0031667(response to nutrient levels);GO:0043473(pigmentation);GO:0043473(pigmentation)","NA","NA","NA","SZT2, KICSTOR complex subunit [Source:HGNC Symbol;Acc:HGNC:29040]",{"v":1.73477621348888,"d":"1.73"},{"v":0.423426580289104,"d":"0.42"},{"v":4.09699412895719,"d":"4.10"},{"v":2.03456582542002,"d":"2.03"},{"v":0.00898446785497816,"d":"0.01"},{"v":0.253280595328287,"d":"0.25"},"up","yes"]
["MSTRG.3129","KLRF1","ENST00000617889;ENST00000617793;ENST00000616259;ENST00000279545;ENST00000612321;ENST00000537723;ENST00000545196;ENST00000354855","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0030246(carbohydrate binding);GO:0050776(regulation of immune response);GO:0005886(plasma membrane);GO:0005887(integral component of plasma membrane);GO:0007166(cell surface receptor signaling pathway);GO:0004888(transmembrane signaling receptor activity);GO:0032393(MHC class I receptor activity);GO:0032393(MHC class I receptor activity)","NA","NA","NA","killer cell lectin like receptor F1 [Source:HGNC Symbol;Acc:HGNC:13342]",{"v":11.2824709261905,"d":"11.28"},{"v":31.7454439722222,"d":"31.75"},{"v":0.355404414443309,"d":"0.36"},{"v":-1.49246649383614,"d":"-1.49"},{"v":0.00898575779516528,"d":"0.01"},{"v":0.253280595328287,"d":"0.25"},"down","yes"]
["MSTRG.7628","MOB3A","MSTRG.7628.1;ENST00000357066;ENST00000592280;ENST00000592143;ENST00000591326;ENST00000589902;ENST00000591236;ENST00000591638;ENST00000588048;MSTRG.7628.2;ENST00000586676","GO:0046872(metal ion binding);GO:0005622(intracellular);GO:0005622(intracellular)","NA","NA","NA","MOB kinase activator 3A [Source:HGNC Symbol;Acc:HGNC:29802]",{"v":51.7562221757885,"d":"51.76"},{"v":12.7090723935529,"d":"12.71"},{"v":4.07238392961264,"d":"4.07"},{"v":2.02587357989049,"d":"2.03"},{"v":0.00906730542956886,"d":"0.01"},{"v":0.254812243060781,"d":"0.25"},"up","yes"]
["ENSG00000134369","NAV1","ENST00000367302;ENST00000469130;ENST00000593583;ENST00000367295;ENST00000367296","GO:0005737(cytoplasm);GO:0005856(cytoskeleton);GO:0007275(multicellular organism development);GO:0007399(nervous system development);GO:0030154(cell differentiation);GO:0005874(microtubule);GO:0001578(microtubule bundle formation);GO:0001764(neuron migration);GO:0015630(microtubule cytoskeleton);GO:0043194(axon initial segment);GO:0043194(axon initial segment)","NA","NA","NA","neuron navigator 1 [Source:HGNC Symbol;Acc:HGNC:15989]",{"v":0.162830957823008,"d":"0.16"},{"v":0.0368023033893021,"d":"0.04"},{"v":4.42447735133722,"d":"4.42"},{"v":2.14550704453637,"d":"2.15"},{"v":0.00908398076527715,"d":"0.01"},{"v":0.254812243060781,"d":"0.25"},"up","yes"]
["ENSG00000182253","SYNM","ENST00000336292;ENST00000594047;ENST00000560674","GO:0005198(structural molecule activity);GO:0005200(structural constituent of cytoskeleton);GO:0005882(intermediate filament);GO:0008307(structural constituent of muscle);GO:0045104(intermediate filament cytoskeleton organization);GO:0005737(cytoplasm);GO:0045111(intermediate filament cytoskeleton);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0030054(cell junction);GO:0005912(adherens junction);GO:0017166(vinculin binding);GO:0019215(intermediate filament binding);GO:0031443(fast-twitch skeletal muscle fiber contraction);GO:0016020(membrane);GO:0042383(sarcolemma);GO:0043034(costamere);GO:0060053(neurofilament cytoskeleton);GO:0060053(neurofilament cytoskeleton)","NA","NA","NA","synemin [Source:HGNC Symbol;Acc:HGNC:24466]",{"v":0.604585290190562,"d":"0.60"},{"v":0.141898793963422,"d":"0.14"},{"v":4.26067955409409,"d":"4.26"},{"v":2.09108355043566,"d":"2.09"},{"v":0.00912132899093368,"d":"0.01"},{"v":0.255243358004127,"d":"0.26"},"up","yes"]
["ENSG00000180747","SMG1P3","ENST00000522480;ENST00000522841;ENST00000437413;ENST00000440195;ENST00000435197;ENST00000520823","NA","NA","NA","NA","SMG1P3, nonsense mediated mRNA decay associated PI3K related kinase pseudogene 3 [Source:HGNC Symbol;Acc:HGNC:49860]",{"v":1.95560616969185,"d":"1.96"},{"v":0.473766973969326,"d":"0.47"},{"v":4.12778069629325,"d":"4.13"},{"v":2.04536632425567,"d":"2.05"},{"v":0.0092029650658575,"d":"0.01"},{"v":0.256908733917796,"d":"0.26"},"up","yes"]
["MSTRG.5249","AC064799.1","ENST00000498103","NA","NA","NA","NA",null,{"v":3.213731,"d":"3.21"},{"v":9.245924,"d":"9.25"},{"v":0.347583540595834,"d":"0.35"},{"v":-1.5245683282212,"d":"-1.52"},{"v":0.00930706555146871,"d":"0.01"},{"v":0.259191732012485,"d":"0.26"},"down","yes"]
["MSTRG.7276","TNRC6C","ENST00000301624;ENST00000636222;ENST00000587990;ENST00000592566;ENST00000592251;ENST00000335749;ENST00000591851;ENST00000588847;ENST00000585438","GO:0003676(nucleic acid binding);GO:0035278(miRNA mediated inhibition of translation);GO:0035195(gene silencing by miRNA);GO:0003723(RNA binding);GO:0005515(protein binding);GO:0031047(gene silencing by RNA);GO:0005829(cytosol);GO:0006417(regulation of translation);GO:0060213(positive regulation of nuclear-transcribed mRNA poly(A) tail shortening);GO:1900153(positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay);GO:0038111(interleukin-7-mediated signaling pathway);GO:0048015(phosphatidylinositol-mediated signaling);GO:0045652(regulation of megakaryocyte differentiation);GO:0007223(Wnt signaling pathway, calcium modulating pathway);GO:0035194(posttranscriptional gene silencing by RNA);GO:0035194(posttranscriptional gene silencing by RNA)","NA","NA","NA","trinucleotide repeat containing 6C [Source:HGNC Symbol;Acc:HGNC:29318]",{"v":3.52871041364414,"d":"3.53"},{"v":0.86752634695347,"d":"0.87"},{"v":4.06755417404447,"d":"4.07"},{"v":2.02416156067465,"d":"2.02"},{"v":0.00939758237612121,"d":"0.01"},{"v":0.261086421372956,"d":"0.26"},"up","yes"]
["MSTRG.921","ENSA","ENST00000369014;ENST00000271690;ENST00000503345;ENST00000362052;ENST00000638926;ENST00000361532;ENST00000356527;ENST00000361631;ENST00000513281;ENST00000369016;ENST00000339643;ENST00000503241;ENST00000354702","GO:0005737(cytoplasm);GO:0051301(cell division);GO:0050790(regulation of catalytic activity);GO:0005515(protein binding);GO:0043086(negative regulation of catalytic activity);GO:0007049(cell cycle);GO:0065009(regulation of molecular function);GO:0004864(protein phosphatase inhibitor activity);GO:0005654(nucleoplasm);GO:0006810(transport);GO:0005102(receptor binding);GO:0000278(mitotic cell cycle);GO:0007584(response to nutrient);GO:0008200(ion channel inhibitor activity);GO:0019212(phosphatase inhibitor activity);GO:0019870(potassium channel inhibitor activity);GO:0019888(protein phosphatase regulator activity);GO:0051721(protein phosphatase 2A binding);GO:0000086(G2/M transition of mitotic cell cycle);GO:0035308(negative regulation of protein dephosphorylation);GO:0050796(regulation of insulin secretion);GO:0009749(response to glucose);GO:0009749(response to glucose)","NA","NA","NA","endosulfine alpha [Source:HGNC Symbol;Acc:HGNC:3360]",{"v":4.92100085344985,"d":"4.92"},{"v":13.7159140309485,"d":"13.72"},{"v":0.358780380392159,"d":"0.36"},{"v":-1.47882709505617,"d":"-1.48"},{"v":0.00945599540252437,"d":"0.01"},{"v":0.262082278304333,"d":"0.26"},"down","yes"]
["ENSG00000178385","PLEKHM3","ENST00000427836;ENST00000447645;ENST00000457206","GO:0046872(metal ion binding);GO:0046872(metal ion binding)","NA","NA","NA","pleckstrin homology domain containing M3 [Source:HGNC Symbol;Acc:HGNC:34006]",{"v":1.98359846636963,"d":"1.98"},{"v":0.488091306143432,"d":"0.49"},{"v":4.06399057185158,"d":"4.06"},{"v":2.02289705517141,"d":"2.02"},{"v":0.00957044050173763,"d":"0.01"},{"v":0.263608361618292,"d":"0.26"},"up","yes"]
["MSTRG.7715","MLLT1","ENST00000252674;ENST00000587473;ENST00000585588","GO:0005634(nucleus);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0001650(fibrillar center);GO:0005515(protein binding);GO:0003677(DNA binding);GO:0006366(transcription from RNA polymerase II promoter);GO:0006368(transcription elongation from RNA polymerase II promoter);GO:0008023(transcription elongation factor complex);GO:0006469(negative regulation of protein kinase activity);GO:0006469(negative regulation of protein kinase activity)","05202(Transcriptional misregulation in cancers);05202(Transcriptional misregulation in cancers)","K15187","NA","MLLT1, super elongation complex subunit [Source:HGNC Symbol;Acc:HGNC:7134]",{"v":11.0138507755274,"d":"11.01"},{"v":2.72182994852321,"d":"2.72"},{"v":4.04648746755954,"d":"4.05"},{"v":2.01667012727852,"d":"2.02"},{"v":0.00957233482111654,"d":"0.01"},{"v":0.263608361618292,"d":"0.26"},"up","yes"]
["MSTRG.976","S100A6","ENST00000496817;ENST00000368719;ENST00000462776;ENST00000368720;ENST00000462951","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0046872(metal ion binding);GO:0005829(cytosol);GO:0034220(ion transmembrane transport);GO:0005509(calcium ion binding);GO:0042803(protein homodimerization activity);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0007165(signal transduction);GO:0048471(perinuclear region of cytoplasm);GO:0031234(extrinsic component of cytoplasmic side of plasma membrane);GO:0007409(axonogenesis);GO:0070062(extracellular exosome);GO:0048306(calcium-dependent protein binding);GO:0001726(ruffle);GO:0005635(nuclear envelope);GO:0044548(S100 protein binding);GO:0048146(positive regulation of fibroblast proliferation);GO:0005523(tropomyosin binding);GO:0008270(zinc ion binding);GO:0015075(ion transmembrane transporter activity);GO:0015075(ion transmembrane transporter activity)","NA","NA","NA","S100 calcium binding protein A6 [Source:HGNC Symbol;Acc:HGNC:10496]",{"v":93.6852467785788,"d":"93.69"},{"v":259.973236514933,"d":"259.97"},{"v":0.360364966926884,"d":"0.36"},{"v":-1.47246932928948,"d":"-1.47"},{"v":0.00957915513673635,"d":"0.01"},{"v":0.263608361618292,"d":"0.26"},"down","yes"]
["ENSG00000152642","GPD1L","ENST00000282541;ENST00000474846;ENST00000428684;ENST00000496151;ENST00000425459","GO:0055114(oxidation-reduction process);GO:0016616(oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor);GO:0004367(glycerol-3-phosphate dehydrogenase [NAD+] activity);GO:0051287(NAD binding);GO:0006072(glycerol-3-phosphate metabolic process);GO:0046168(glycerol-3-phosphate catabolic process);GO:0009331(glycerol-3-phosphate dehydrogenase complex);GO:0060373(regulation of ventricular cardiac muscle cell membrane depolarization);GO:0002027(regulation of heart rate);GO:0005737(cytoplasm);GO:0016491(oxidoreductase activity);GO:0005975(carbohydrate metabolic process);GO:0042803(protein homodimerization activity);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0017080(sodium channel regulator activity);GO:0044325(ion channel binding);GO:2000649(regulation of sodium ion transmembrane transporter activity);GO:0005886(plasma membrane);GO:0006654(phosphatidic acid biosynthetic process);GO:0033137(negative regulation of peptidyl-serine phosphorylation);GO:2000010(positive regulation of protein localization to cell surface);GO:0086005(ventricular cardiac muscle cell action potential);GO:0010765(positive regulation of sodium ion transport);GO:0006734(NADH metabolic process);GO:0019674(NAD metabolic process);GO:0090038(negative regulation of protein kinase C signaling);GO:0016020(membrane);GO:0016020(membrane)","00564(Glycerophospholipid metabolism);00564(Glycerophospholipid metabolism)","K00006","EC:1.1.1.8","glycerol-3-phosphate dehydrogenase 1 like [Source:HGNC Symbol;Acc:HGNC:28956]",{"v":3.15103783236152,"d":"3.15"},{"v":0.769627852769679,"d":"0.77"},{"v":4.09423570238759,"d":"4.09"},{"v":2.03359415973245,"d":"2.03"},{"v":0.00962782034952713,"d":"0.01"},{"v":0.263951704523222,"d":"0.26"},"up","yes"]
["MSTRG.249","RUNX3","ENST00000308873;ENST00000399916;ENST00000496967","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0043231(intracellular membrane-bounded organelle);GO:0005524(ATP binding);GO:0005730(nucleolus);GO:0005829(cytosol);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0005515(protein binding);GO:0045893(positive regulation of transcription, DNA-templated);GO:0005654(nucleoplasm);GO:0000981(RNA polymerase II transcription factor activity, sequence-specific DNA binding);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0045786(negative regulation of cell cycle);GO:0000790(nuclear chromatin);GO:0006366(transcription from RNA polymerase II promoter);GO:0006468(protein phosphorylation);GO:0000977(RNA polymerase II regulatory region sequence-specific DNA binding);GO:0050680(negative regulation of epithelial cell proliferation);GO:0030097(hemopoiesis);GO:0048935(peripheral nervous system neuron development);GO:0001503(ossification);GO:0002062(chondrocyte differentiation);GO:0071559(response to transforming growth factor beta);GO:0045595(regulation of cell differentiation);GO:0045595(regulation of cell differentiation)","04658(Th1 and Th2 cell differentiation);04658(Th1 and Th2 cell differentiation)","K09279","NA","runt related transcription factor 3 [Source:HGNC Symbol;Acc:HGNC:10473]",{"v":25.5374832816715,"d":"25.54"},{"v":6.33379943466726,"d":"6.33"},{"v":4.03193747214275,"d":"4.03"},{"v":2.01147326549233,"d":"2.01"},{"v":0.00963708970273366,"d":"0.01"},{"v":0.263951704523222,"d":"0.26"},"up","yes"]
["MSTRG.926",null,"MSTRG.926.1","NA","NA","NA","NA",null,{"v":7.193897,"d":"7.19"},{"v":1.76133,"d":"1.76"},{"v":4.08435500445686,"d":"4.08"},{"v":2.03010826800578,"d":"2.03"},{"v":0.00967461525111735,"d":"0.01"},{"v":0.264356016261708,"d":"0.26"},"up","yes"]
["MSTRG.2356","ARHGAP1","ENST00000311956;ENST00000527588;ENST00000528837;ENST00000529960;ENST00000526423;ENST00000524594","GO:0005737(cytoplasm);GO:0007165(signal transduction);GO:0009967(positive regulation of signal transduction);GO:0043547(positive regulation of GTPase activity);GO:0005515(protein binding);GO:0005096(GTPase activator activity);GO:0005829(cytosol);GO:0045296(cadherin binding);GO:0070062(extracellular exosome);GO:0051056(regulation of small GTPase mediated signal transduction);GO:0017124(SH3 domain binding);GO:0007266(Rho protein signal transduction);GO:0005070(SH3/SH2 adaptor activity);GO:0010008(endosome membrane);GO:0048471(perinuclear region of cytoplasm);GO:0097443(sorting endosome);GO:0017137(Rab GTPase binding);GO:0007264(small GTPase mediated signal transduction);GO:0032439(endosome localization);GO:0033572(transferrin transport);GO:0098706(ferric iron import across plasma membrane);GO:2001136(negative regulation of endocytic recycling);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016021(integral component of membrane)","NA","NA","NA","Rho GTPase activating protein 1 [Source:HGNC Symbol;Acc:HGNC:673]",{"v":12.2123804470512,"d":"12.21"},{"v":3.02516115705442,"d":"3.03"},{"v":4.03693549303083,"d":"4.04"},{"v":2.01326053390089,"d":"2.01"},{"v":0.0096988603202029,"d":"0.01"},{"v":0.26439639647539,"d":"0.26"},"up","yes"]
["MSTRG.12584","TMED9","ENST00000332598;ENST00000507723;ENST00000507578;ENST00000513799;ENST00000510499;ENST00000505521","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0015031(protein transport);GO:0005794(Golgi apparatus);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005515(protein binding);GO:0070062(extracellular exosome);GO:0006890(retrograde vesicle-mediated transport, Golgi to ER);GO:0019905(syntaxin binding);GO:0030140(trans-Golgi network transport vesicle);GO:0006888(ER to Golgi vesicle-mediated transport);GO:0000139(Golgi membrane);GO:0030133(transport vesicle);GO:0033116(endoplasmic reticulum-Golgi intermediate compartment membrane);GO:0007030(Golgi organization);GO:0010638(positive regulation of organelle organization);GO:0005793(endoplasmic reticulum-Golgi intermediate compartment);GO:0048205(COPI coating of Golgi vesicle);GO:0048205(COPI coating of Golgi vesicle)","NA","NA","NA","transmembrane p24 trafficking protein 9 [Source:HGNC Symbol;Acc:HGNC:24878]",{"v":5.67767544303279,"d":"5.68"},{"v":15.7871128922131,"d":"15.79"},{"v":0.359639883606158,"d":"0.36"},{"v":-1.47537507211579,"d":"-1.48"},{"v":0.00976110652940561,"d":"0.01"},{"v":0.265001701494533,"d":"0.27"},"down","yes"]
["ENSG00000038382","TRIO","ENST00000344204;ENST00000515144;ENST00000505971;ENST00000508343;ENST00000512303;ENST00000639876;ENST00000513206;ENST00000620511;ENST00000508283;ENST00000515710;ENST00000503399;ENST00000511019;ENST00000506611;ENST00000509354;ENST00000512070;ENST00000510281;ENST00000509967;ENST00000508717","GO:0005737(cytoplasm);GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0005089(Rho guanyl-nucleotide exchange factor activity);GO:0035023(regulation of Rho protein signal transduction);GO:0043547(positive regulation of GTPase activity);GO:0005515(protein binding);GO:0005085(guanyl-nucleotide exchange factor activity);GO:0005829(cytosol);GO:0051056(regulation of small GTPase mediated signal transduction);GO:0043065(positive regulation of apoptotic process);GO:0019899(enzyme binding);GO:0007185(transmembrane receptor protein tyrosine phosphatase signaling pathway);GO:0007185(transmembrane receptor protein tyrosine phosphatase signaling pathway)","NA","NA","NA","trio Rho guanine nucleotide exchange factor [Source:HGNC Symbol;Acc:HGNC:12303]",{"v":1.77836377325714,"d":"1.78"},{"v":0.435350351828571,"d":"0.44"},{"v":4.08490257510441,"d":"4.08"},{"v":2.03030167051543,"d":"2.03"},{"v":0.00976670354255234,"d":"0.01"},{"v":0.265001701494533,"d":"0.27"},"up","yes"]
["MSTRG.4306","AP4S1","ENST00000542754;ENST00000216366;ENST00000556480;ENST00000556232;ENST00000313566","GO:0006810(transport);GO:0008565(protein transporter activity);GO:0015031(protein transport);GO:0016020(membrane);GO:0005794(Golgi apparatus);GO:0005905(clathrin-coated pit);GO:0005215(transporter activity);GO:0031904(endosome lumen);GO:0032588(trans-Golgi network membrane);GO:0032588(trans-Golgi network membrane)","04142(Lysosome);04142(Lysosome)","K12403","NA","adaptor related protein complex 4 sigma 1 subunit [Source:HGNC Symbol;Acc:HGNC:575]",{"v":0.259663690156445,"d":"0.26"},{"v":0.744362500484563,"d":"0.74"},{"v":0.348840370098453,"d":"0.35"},{"v":-1.51936108696676,"d":"-1.52"},{"v":0.00990042135149361,"d":"0.01"},{"v":0.267710439993191,"d":"0.27"},"down","yes"]
["MSTRG.7602","MIDN","ENST00000591446;ENST00000300952;ENST00000586843;ENST00000590136;ENST00000591302","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005730(nucleolus);GO:0003674(molecular_function);GO:0008150(biological_process);GO:0019900(kinase binding);GO:0046676(negative regulation of insulin secretion);GO:0033132(negative regulation of glucokinase activity);GO:0033132(negative regulation of glucokinase activity)","NA","NA","NA","midnolin [Source:HGNC Symbol;Acc:HGNC:16298]",{"v":25.9310607052538,"d":"25.93"},{"v":6.46963899621549,"d":"6.47"},{"v":4.00811555643561,"d":"4.01"},{"v":2.00292410291769,"d":"2.00"},{"v":0.00997128098639655,"d":"0.01"},{"v":0.267710439993191,"d":"0.27"},"up","yes"]
["MSTRG.1269","B3GALT2","ENST00000367434","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016740(transferase activity);GO:0016757(transferase activity, transferring glycosyl groups);GO:0006486(protein glycosylation);GO:0005794(Golgi apparatus);GO:0000139(Golgi membrane);GO:0008378(galactosyltransferase activity);GO:0008499(UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity);GO:0047275(glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity);GO:0006682(galactosylceramide biosynthetic process);GO:0009312(oligosaccharide biosynthetic process)","00601(Glycosphingolipid biosynthesis - lacto and neolacto series)","K07820","EC:2.4.1.86","beta-1,3-galactosyltransferase 2 [Source:HGNC Symbol;Acc:HGNC:917]",{"v":1.247425,"d":"1.25"},{"v":0.296679,"d":"0.30"},{"v":4.20462857162118,"d":"4.20"},{"v":2.07197836134896,"d":"2.07"},{"v":0.00998753491444712,"d":"0.01"},{"v":0.267710439993191,"d":"0.27"},"up","yes"]
["MSTRG.7729","RFX2","ENST00000303657;ENST00000592546;ENST00000589340;ENST00000588021;ENST00000590822;ENST00000587181;ENST00000589742;ENST00000593241;ENST00000590778;ENST00000359161;ENST00000592337;ENST00000586806;ENST00000586940;ENST00000587700","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0005515(protein binding);GO:0030154(cell differentiation);GO:0007283(spermatogenesis);GO:0060271(cilium assembly);GO:0030030(cell projection organization);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:0007286(spermatid development);GO:0000977(RNA polymerase II regulatory region sequence-specific DNA binding);GO:0001675(acrosome assembly);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:1990830(cellular response to leukemia inhibitory factor);GO:1990830(cellular response to leukemia inhibitory factor)","NA","NA","NA","regulatory factor X2 [Source:HGNC Symbol;Acc:HGNC:9983]",{"v":3.39482906685727,"d":"3.39"},{"v":0.840220717945898,"d":"0.84"},{"v":4.04040152111063,"d":"4.04"},{"v":2.01449867013824,"d":"2.01"},{"v":0.0099880290799359,"d":"0.01"},{"v":0.267710439993191,"d":"0.27"},"up","yes"]
["MSTRG.9843","CASS4","ENST00000434344;MSTRG.9843.1;ENST00000497244;ENST00000360314","GO:0005737(cytoplasm);GO:0007155(cell adhesion);GO:0005856(cytoskeleton);GO:0030054(cell junction);GO:0005925(focal adhesion);GO:0005925(focal adhesion)","NA","NA","NA","Cas scaffolding protein family member 4 [Source:HGNC Symbol;Acc:HGNC:15878]",{"v":12.6528506750606,"d":"12.65"},{"v":3.15363922010819,"d":"3.15"},{"v":4.0121427316047,"d":"4.01"},{"v":2.004372930605,"d":"2.00"},{"v":0.00999099123690943,"d":"0.01"},{"v":0.267710439993191,"d":"0.27"},"up","yes"]
["MSTRG.3701","KCTD10","ENST00000228495;ENST00000538377;ENST00000541077;ENST00000540355;ENST00000540402;ENST00000540089;ENST00000535747;ENST00000545759;ENST00000537165","GO:0005634(nucleus);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0016567(protein ubiquitination);GO:0051260(protein homooligomerization);GO:0005515(protein binding);GO:0004842(ubiquitin-protein transferase activity);GO:0043161(proteasome-mediated ubiquitin-dependent protein catabolic process);GO:0031463(Cul3-RING ubiquitin ligase complex);GO:0005112(Notch binding);GO:0006511(ubiquitin-dependent protein catabolic process);GO:0006511(ubiquitin-dependent protein catabolic process)","NA","NA","NA","potassium channel tetramerization domain containing 10 [Source:HGNC Symbol;Acc:HGNC:23236]",{"v":3.2876693064369,"d":"3.29"},{"v":0.81458485646224,"d":"0.81"},{"v":4.0360059241898,"d":"4.04"},{"v":2.01292829208376,"d":"2.01"},{"v":0.0100267580190509,"d":"0.01"},{"v":0.267710439993191,"d":"0.27"},"up","yes"]
["MSTRG.9681","TP53INP2","ENST00000374810;ENST00000414082","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0045893(positive regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0005829(cytosol);GO:0006914(autophagy);GO:0031410(cytoplasmic vesicle);GO:0005515(protein binding);GO:0000045(autophagosome assembly);GO:0005776(autophagosome);GO:0010508(positive regulation of autophagy);GO:0016605(PML body);GO:0043130(ubiquitin binding);GO:0001649(osteoblast differentiation);GO:0001894(tissue homeostasis);GO:0006511(ubiquitin-dependent protein catabolic process);GO:0016236(macroautophagy);GO:1903828(negative regulation of cellular protein localization);GO:1903828(negative regulation of cellular protein localization)","04140(Autophagy - animal);04140(Autophagy - animal)","K21247","NA","tumor protein p53 inducible nuclear protein 2 [Source:HGNC Symbol;Acc:HGNC:16104]",{"v":5.04809495931883,"d":"5.05"},{"v":1.24903116745506,"d":"1.25"},{"v":4.04160848091924,"d":"4.04"},{"v":2.01492957159541,"d":"2.01"},{"v":0.0100279033322172,"d":"0.01"},{"v":0.267710439993191,"d":"0.27"},"up","yes"]
["ENSG00000173611","SCAI","ENST00000336505;ENST00000468569;ENST00000373549;ENST00000494102","GO:0006351(transcription, DNA-templated);GO:0003714(transcription corepressor activity);GO:1903507(negative regulation of nucleic acid-templated transcription);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0006355(regulation of transcription, DNA-templated);GO:0031965(nuclear membrane);GO:0005515(protein binding);GO:0005654(nucleoplasm);GO:0009968(negative regulation of signal transduction);GO:0030336(negative regulation of cell migration);GO:0035024(negative regulation of Rho protein signal transduction);GO:0035024(negative regulation of Rho protein signal transduction)","NA","NA","NA","suppressor of cancer cell invasion [Source:HGNC Symbol;Acc:HGNC:26709]",{"v":0.753205029967727,"d":"0.75"},{"v":0.185195412402029,"d":"0.19"},{"v":4.0670825491759,"d":"4.07"},{"v":2.02399427333707,"d":"2.02"},{"v":0.0100690140577368,"d":"0.01"},{"v":0.26819142259747,"d":"0.27"},"up","yes"]
["MSTRG.886","NBPF14","MSTRG.886.3;ENST00000593495;ENST00000619423;ENST00000606877;ENST00000621066;ENST00000614329;ENST00000620240;ENST00000611826;ENST00000614999;ENST00000581201","GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0005509(calcium ion binding);GO:0005509(calcium ion binding)","NA","NA","NA","NBPF member 14 [Source:HGNC Symbol;Acc:HGNC:25232]",{"v":8.47081526048201,"d":"8.47"},{"v":2.11758172457907,"d":"2.12"},{"v":4.00023062258238,"d":"4.00"},{"v":2.00008317711619,"d":"2.00"},{"v":0.0100996488164747,"d":"0.01"},{"v":0.268391811683571,"d":"0.27"},"up","yes"]
["ENSG00000197619","ZNF615","ENST00000598071;ENST00000599631;ENST00000594083;ENST00000391795;ENST00000602063;ENST00000597747","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0005622(intracellular);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding)","NA","NA","NA","zinc finger protein 615 [Source:HGNC Symbol;Acc:HGNC:24740]",{"v":0.916749363747704,"d":"0.92"},{"v":0.217012456419677,"d":"0.22"},{"v":4.22440895270462,"d":"4.22"},{"v":2.07874950455437,"d":"2.08"},{"v":0.0101496084661067,"d":"0.01"},{"v":0.269103660084241,"d":"0.27"},"up","yes"]
["MSTRG.9679","NCOA6;PIGU","ENST00000612493;MSTRG.9679.16;ENST00000217446;ENST00000462389;ENST00000359003;ENST00000616167;ENST00000374820;ENST00000480175;ENST00000471897;ENST00000374796","GO:0005634(nucleus);GO:0043231(intracellular membrane-bounded organelle);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0005515(protein binding);GO:0006281(DNA repair);GO:0006310(DNA recombination);GO:0006260(DNA replication);GO:0003713(transcription coactivator activity);GO:0030374(ligand-dependent nuclear receptor transcription coactivator activity);GO:0045893(positive regulation of transcription, DNA-templated);GO:0006367(transcription initiation from RNA polymerase II promoter);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0007507(heart development);GO:0030331(estrogen receptor binding);GO:0003682(chromatin binding);GO:0019899(enzyme binding);GO:0035097(histone methyltransferase complex);GO:0006352(DNA-templated transcription, initiation);GO:0007420(brain development);GO:0030520(intracellular estrogen receptor signaling pathway);GO:0042921(glucocorticoid receptor signaling pathway);GO:0019216(regulation of lipid metabolic process);GO:0006974(cellular response to DNA damage stimulus);GO:0005667(transcription factor complex);GO:0046966(thyroid hormone receptor binding);GO:0009725(response to hormone);GO:0046965(retinoid X receptor binding);GO:0030099(myeloid cell differentiation);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0006506(GPI anchor biosynthetic process);GO:0016255(attachment of GPI anchor to protein);GO:0042765(GPI-anchor transamidase complex);GO:0005886(plasma membrane);GO:0030176(integral component of endoplasmic reticulum membrane);GO:0003923(GPI-anchor transamidase activity);GO:0034235(GPI anchor binding);GO:0046425(regulation of JAK-STAT cascade);GO:0030099(myeloid cell differentiation)","00563(Glycosylphosphatidylinositol(GPI)-anchor biosynthesis);00563(Glycosylphosphatidylinositol(GPI)-anchor biosynthesis)","K05293","NA","nuclear receptor coactivator 6 [Source:HGNC Symbol;Acc:HGNC:15936];phosphatidylinositol glycan anchor biosynthesis class U [Source:HGNC Symbol;Acc:HGNC:15791]",{"v":5.1138691919214,"d":"5.11"},{"v":1.27847881790393,"d":"1.28"},{"v":3.99996395740495,"d":"4.00"},{"v":1.99998700032315,"d":"2.00"},{"v":0.0102349154732728,"d":"0.01"},{"v":0.270747319797532,"d":"0.27"},"up","yes"]
["ENSG00000101888","NXT2","ENST00000372106;ENST00000218004;ENST00000372107;ENST00000372103","GO:0006810(transport);GO:0051028(mRNA transport);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0015031(protein transport);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0005622(intracellular);GO:0005515(protein binding);GO:0048471(perinuclear region of cytoplasm);GO:0048471(perinuclear region of cytoplasm)","03013(RNA transport);03015(mRNA surveillance pathway);03008(Ribosome biogenesis in eukaryotes);05164(Influenza A);05164(Influenza A)","K14285","NA","nuclear transport factor 2 like export factor 2 [Source:HGNC Symbol;Acc:HGNC:18151]",{"v":2.38899890665796,"d":"2.39"},{"v":0.576485641971279,"d":"0.58"},{"v":4.14407356007833,"d":"4.14"},{"v":2.05104961205398,"d":"2.05"},{"v":0.0103729042029437,"d":"0.01"},{"v":0.273408571781229,"d":"0.27"},"up","yes"]
["MSTRG.5174","SNX22","ENST00000325881;ENST00000561334;ENST00000557789;ENST00000560945;ENST00000560607;ENST00000560997","GO:0006810(transport);GO:0016020(membrane);GO:0015031(protein transport);GO:0030659(cytoplasmic vesicle membrane);GO:0031410(cytoplasmic vesicle);GO:0035091(phosphatidylinositol binding);GO:0008289(lipid binding);GO:0008289(lipid binding)","NA","NA","NA","sorting nexin 22 [Source:HGNC Symbol;Acc:HGNC:16315]",{"v":0.431878322351309,"d":"0.43"},{"v":1.21167040124848,"d":"1.21"},{"v":0.356432179829028,"d":"0.36"},{"v":-1.48830050105793,"d":"-1.49"},{"v":0.0103876783322891,"d":"0.01"},{"v":0.273408571781229,"d":"0.27"},"down","yes"]
["MSTRG.14819","RMI1","ENST00000445877;ENST00000325875","GO:0005654(nucleoplasm);GO:0016604(nuclear body);GO:0005634(nucleus);GO:0005515(protein binding);GO:0000166(nucleotide binding);GO:0006260(DNA replication);GO:1901796(regulation of signal transduction by p53 class mediator);GO:0000731(DNA synthesis involved in DNA repair);GO:0000732(strand displacement);GO:0000732(strand displacement)","03460(Fanconi anemia pathway);03460(Fanconi anemia pathway)","K10990","NA","RecQ mediated genome instability 1 [Source:HGNC Symbol;Acc:HGNC:25764]",{"v":0.209260656971771,"d":"0.21"},{"v":0.625486513829484,"d":"0.63"},{"v":0.334556624875238,"d":"0.33"},{"v":-1.57967768218821,"d":"-1.58"},{"v":0.0104061473114013,"d":"0.01"},{"v":0.273408571781229,"d":"0.27"},"down","yes"]
["MSTRG.6406","NAA38","ENST00000575771;ENST00000333775;ENST00000576384;ENST00000575071;ENST00000576861;ENST00000570555","GO:0005634(nucleus);GO:0031417(NatC complex);GO:0005737(cytoplasm);GO:0005515(protein binding);GO:0043066(negative regulation of apoptotic process);GO:0005844(polysome);GO:0005844(polysome)","NA","NA","NA","N(alpha)-acetyltransferase 38, NatC auxiliary subunit [Source:HGNC Symbol;Acc:HGNC:28212]",{"v":3.38674933556356,"d":"3.39"},{"v":9.34942701183737,"d":"9.35"},{"v":0.362241379207044,"d":"0.36"},{"v":-1.46497673864067,"d":"-1.46"},{"v":0.0104549324375773,"d":"0.01"},{"v":0.274070271777846,"d":"0.27"},"down","yes"]
["ENSG00000198039","ZNF273","ENST00000395375;ENST00000489672;ENST00000527278;ENST00000476120;ENST00000476730","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0005622(intracellular);GO:0005515(protein binding);GO:0005515(protein binding)","NA","NA","NA","zinc finger protein 273 [Source:HGNC Symbol;Acc:HGNC:13067]",{"v":0.0834884386269071,"d":"0.08"},{"v":0.257208883032825,"d":"0.26"},{"v":0.324593916207211,"d":"0.32"},{"v":-1.62329213486574,"d":"-1.62"},{"v":0.0105001704664626,"d":"0.01"},{"v":0.274636215376193,"d":"0.27"},"down","yes"]
["MSTRG.13863","KMT2E","MSTRG.13863.6;ENST00000311117;ENST00000474203;ENST00000468607;ENST00000257745;ENST00000622386;ENST00000480368;ENST00000485619;ENST00000482560;ENST00000478079;ENST00000476671;ENST00000479838;ENST00000496191;ENST00000495267","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016607(nuclear speck);GO:0016020(membrane);GO:0046872(metal ion binding);GO:0008168(methyltransferase activity);GO:0016740(transferase activity);GO:0032259(methylation);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0016569(covalent chromatin modification);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0007049(cell cycle);GO:0030218(erythrocyte differentiation);GO:0018024(histone-lysine N-methyltransferase activity);GO:0034968(histone lysine methylation);GO:0005654(nucleoplasm);GO:0007050(cell cycle arrest);GO:0045652(regulation of megakaryocyte differentiation);GO:0042119(neutrophil activation);GO:0006306(DNA methylation);GO:0002446(neutrophil mediated immunity);GO:0002446(neutrophil mediated immunity)","00310(Lysine degradation);00310(Lysine degradation)","K09189","EC:2.1.1.43","lysine methyltransferase 2E [Source:HGNC Symbol;Acc:HGNC:18541]",{"v":11.4881113889069,"d":"11.49"},{"v":2.88658282992092,"d":"2.89"},{"v":3.97983084698859,"d":"3.98"},{"v":1.99270711383507,"d":"1.99"},{"v":0.0105594863788032,"d":"0.01"},{"v":0.275567000712452,"d":"0.28"},"up","yes"]
["MSTRG.10045","KCNJ15;DSCR8","ENST00000398938;ENST00000398932;ENST00000419868;ENST00000417042;ENST00000613499;ENST00000328656;ENST00000548700;ENST00000438657;ENST00000465532;ENST00000398934;ENST00000398925;ENST00000549805;ENST00000547595;ENST00000547341;MSTRG.10045.17;ENST00000443341;ENST00000398928;MSTRG.10045.16;ENST00000398927;ENST00000398930;ENST00000612702","GO:0016020(membrane);GO:0006813(potassium ion transport);GO:0005242(inward rectifier potassium channel activity);GO:0071805(potassium ion transmembrane transport);GO:0016021(integral component of membrane);GO:0006810(transport);GO:0005244(voltage-gated ion channel activity);GO:0006811(ion transport);GO:0034765(regulation of ion transmembrane transport);GO:0005515(protein binding);GO:0005886(plasma membrane);GO:0005887(integral component of plasma membrane);GO:0010107(potassium ion import);GO:0015467(G-protein activated inward rectifier potassium channel activity);GO:0003674(molecular_function);GO:0008150(biological_process);GO:0005575(cellular_component);GO:0015467(G-protein activated inward rectifier potassium channel activity)","04971(Gastric acid secretion);04971(Gastric acid secretion)","K05008","NA","potassium voltage-gated channel subfamily J member 15 [Source:HGNC Symbol;Acc:HGNC:6261];Down syndrome critical region 8 (non-protein coding) [Source:HGNC Symbol;Acc:HGNC:16707]",{"v":1.40104765101749,"d":"1.40"},{"v":3.85335679578722,"d":"3.85"},{"v":0.363591467197956,"d":"0.36"},{"v":-1.45960975227405,"d":"-1.46"},{"v":0.0105978219869771,"d":"0.01"},{"v":0.275947324517411,"d":"0.28"},"down","yes"]
["MSTRG.2140","OR52K3P","MSTRG.2140.1;ENST00000641797","NA","NA","NA","NA","olfactory receptor family 52 subfamily K member 3 pseudogene [Source:HGNC Symbol;Acc:HGNC:15224]",{"v":0.659545726666667,"d":"0.66"},{"v":1.87552226333333,"d":"1.88"},{"v":0.351659769420422,"d":"0.35"},{"v":-1.50774779767647,"d":"-1.51"},{"v":0.0106627213806716,"d":"0.01"},{"v":0.276339263396498,"d":"0.28"},"down","yes"]
["ENSG00000138829","FBN2","ENST00000262464;ENST00000508989;ENST00000508053;ENST00000502468;ENST00000507835;ENST00000514742","GO:0005509(calcium ion binding);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0005578(proteinaceous extracellular matrix);GO:0005201(extracellular matrix structural constituent);GO:0031012(extracellular matrix);GO:0030501(positive regulation of bone mineralization);GO:0045669(positive regulation of osteoblast differentiation);GO:0030198(extracellular matrix organization);GO:0022617(extracellular matrix disassembly);GO:0043010(camera-type eye development);GO:0030023(extracellular matrix constituent conferring elasticity);GO:0035583(sequestering of TGFbeta in extracellular matrix);GO:0048048(embryonic eye morphogenesis);GO:0090287(regulation of cellular response to growth factor stimulus);GO:0001527(microfibril);GO:0030326(embryonic limb morphogenesis);GO:0035108(limb morphogenesis);GO:0060346(bone trabecula formation);GO:0060346(bone trabecula formation)","NA","NA","NA","fibrillin 2 [Source:HGNC Symbol;Acc:HGNC:3604]",{"v":0.560128411109427,"d":"0.56"},{"v":0.137481094877236,"d":"0.14"},{"v":4.07422134373889,"d":"4.07"},{"v":2.02652436097144,"d":"2.03"},{"v":0.0106761912165956,"d":"0.01"},{"v":0.276339263396498,"d":"0.28"},"up","yes"]
["MSTRG.12880","MPIG6B","ENST00000375809;MSTRG.12880.2;ENST00000375806;ENST00000466312;ENST00000460663;ENST00000471545;ENST00000485548;ENST00000480039;ENST00000375804;ENST00000375814","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005794(Golgi apparatus);GO:0005783(endoplasmic reticulum);GO:0005886(plasma membrane);GO:0030218(erythrocyte differentiation);GO:0007229(integrin-mediated signaling pathway);GO:0005515(protein binding);GO:0008201(heparin binding);GO:0007596(blood coagulation);GO:0030168(platelet activation);GO:0009968(negative regulation of signal transduction);GO:0030219(megakaryocyte differentiation);GO:0030220(platelet formation);GO:0035855(megakaryocyte development);GO:0035855(megakaryocyte development)","NA","NA","NA","megakaryocyte and platelet inhibitory receptor G6b [Source:HGNC Symbol;Acc:HGNC:13937]",{"v":16.3885349841219,"d":"16.39"},{"v":4.12273099079073,"d":"4.12"},{"v":3.97516476838539,"d":"3.98"},{"v":1.99101466054943,"d":"1.99"},{"v":0.0106842615400868,"d":"0.01"},{"v":0.276339263396498,"d":"0.28"},"up","yes"]
["MSTRG.3762","PLBD2","ENST00000280800;ENST00000547163;ENST00000545182","GO:0016787(hydrolase activity);GO:0006629(lipid metabolic process);GO:0016042(lipid catabolic process);GO:0005764(lysosome);GO:0070062(extracellular exosome);GO:0043202(lysosomal lumen);GO:0043202(lysosomal lumen)","NA","NA","NA","phospholipase B domain containing 2 [Source:HGNC Symbol;Acc:HGNC:27283]",{"v":5.41329737338403,"d":"5.41"},{"v":1.36010487756654,"d":"1.36"},{"v":3.98005879007606,"d":"3.98"},{"v":1.99278974120228,"d":"1.99"},{"v":0.0107275052955128,"d":"0.01"},{"v":0.2768411533262,"d":"0.28"},"up","yes"]
["ENSG00000133808","MICALCL","ENST00000256186;ENST00000529028;ENST00000533534","GO:0005737(cytoplasm);GO:0007275(multicellular organism development);GO:0030154(cell differentiation);GO:0007283(spermatogenesis);GO:0008150(biological_process);GO:0051019(mitogen-activated protein kinase binding);GO:0051019(mitogen-activated protein kinase binding)","NA","NA","NA","MICAL C-terminal like [Source:HGNC Symbol;Acc:HGNC:25933]",{"v":1.69358918271462,"d":"1.69"},{"v":0.409364897331786,"d":"0.41"},{"v":4.13711384086258,"d":"4.14"},{"v":2.04862465672418,"d":"2.05"},{"v":0.010781416584296,"d":"0.01"},{"v":0.277615500650619,"d":"0.28"},"up","yes"]
["MSTRG.5867","SRCAP;AC106886.5;PHKG2;TMEM265","ENST00000262518;ENST00000380361;ENST00000563913;ENST00000563588;ENST00000564838;ENST00000328273;MSTRG.5867.1;ENST00000615541;ENST00000483083;ENST00000569762;ENST00000561712;ENST00000569684;ENST00000565897;ENST00000411466;ENST00000474008;ENST00000395059;ENST00000563607","GO:0005634(nucleus);GO:0005794(Golgi apparatus);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0005654(nucleoplasm);GO:0016787(hydrolase activity);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0016569(covalent chromatin modification);GO:0003677(DNA binding);GO:0004386(helicase activity);GO:0016604(nuclear body);GO:0016573(histone acetylation);GO:0048471(perinuclear region of cytoplasm);GO:0043234(protein complex);GO:0016032(viral process);GO:0005515(protein binding);GO:0003713(transcription coactivator activity);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0004402(histone acetyltransferase activity);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0006468(protein phosphorylation);GO:0005829(cytosol);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0005975(carbohydrate metabolic process);GO:0005516(calmodulin binding);GO:0004689(phosphorylase kinase activity);GO:0005978(glycogen biosynthetic process);GO:0005964(phosphorylase kinase complex);GO:0035556(intracellular signal transduction);GO:0005575(cellular_component);GO:0018105(peptidyl-serine phosphorylation);GO:0006091(generation of precursor metabolites and energy);GO:0018107(peptidyl-threonine phosphorylation);GO:0005980(glycogen catabolic process);GO:0005977(glycogen metabolic process);GO:0019899(enzyme binding);GO:0050321(tau-protein kinase activity);GO:0045819(positive regulation of glycogen catabolic process);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0009607(response to biotic stimulus);GO:0045819(positive regulation of glycogen catabolic process)","04020(Calcium signaling pathway);04910(Insulin signaling pathway);04922(Glucagon signaling pathway);04922(Glucagon signaling pathway)","K00871","EC:2.7.11.19","Snf2 related CREBBP activator protein [Source:HGNC Symbol;Acc:HGNC:16974];phosphorylase kinase catalytic subunit gamma 2 [Source:HGNC Symbol;Acc:HGNC:8931];transmembrane protein 265 [Source:HGNC Symbol;Acc:HGNC:51241]",{"v":6.21261620115774,"d":"6.21"},{"v":1.57181946656142,"d":"1.57"},{"v":3.95249984703951,"d":"3.95"},{"v":1.98276540675181,"d":"1.98"},{"v":0.0109046186410286,"d":"0.01"},{"v":0.279191227387,"d":"0.28"},"up","yes"]
["ENSG00000147234","FRMPD3","ENST00000276185","GO:0005856(cytoskeleton);GO:0005886(plasma membrane);GO:0043312(neutrophil degranulation);GO:0070821(tertiary granule membrane);GO:0030667(secretory granule membrane)","NA","NA","NA","FERM and PDZ domain containing 3 [Source:HGNC Symbol;Acc:HGNC:29382]",{"v":0.353712829001965,"d":"0.35"},{"v":0.0830987516925093,"d":"0.08"},{"v":4.25653601044225,"d":"4.26"},{"v":2.08967983573464,"d":"2.09"},{"v":0.0109092779192707,"d":"0.01"},{"v":0.279191227387,"d":"0.28"},"up","yes"]
["MSTRG.5716","SMG1","ENST00000446231;ENST00000563448;ENST00000569122;ENST00000569764;ENST00000566328;ENST00000561940;ENST00000568239;ENST00000532700;ENST00000563235;ENST00000561947;ENST00000568038;ENST00000567737","GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0004674(protein serine/threonine kinase activity);GO:0005524(ATP binding);GO:0005654(nucleoplasm);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0000184(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay);GO:0005515(protein binding);GO:0006281(DNA repair);GO:0006974(cellular response to DNA damage stimulus);GO:0006406(mRNA export from nucleus);GO:0005829(cytosol);GO:0004672(protein kinase activity);GO:0046777(protein autophosphorylation);GO:0006950(response to stress);GO:0042162(telomeric DNA binding);GO:0032204(regulation of telomere maintenance);GO:0018105(peptidyl-serine phosphorylation);GO:0046854(phosphatidylinositol phosphorylation);GO:0006468(protein phosphorylation);GO:0006468(protein phosphorylation)","03015(mRNA surveillance pathway);03015(mRNA surveillance pathway)","K08873","EC:2.7.11.1","SMG1, nonsense mediated mRNA decay associated PI3K related kinase [Source:HGNC Symbol;Acc:HGNC:30045]",{"v":6.71122654452055,"d":"6.71"},{"v":1.70024890441742,"d":"1.70"},{"v":3.94720239318143,"d":"3.95"},{"v":1.98083049545425,"d":"1.98"},{"v":0.0109147349723326,"d":"0.01"},{"v":0.279191227387,"d":"0.28"},"up","yes"]
["MSTRG.2704","KCNE3","ENST00000310128;ENST00000525550;ENST00000531854;MSTRG.2704.2;ENST00000529425","GO:1903817(negative regulation of voltage-gated potassium channel activity);GO:0006810(transport);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0006811(ion transport);GO:0005244(voltage-gated ion channel activity);GO:0005249(voltage-gated potassium channel activity);GO:0005267(potassium channel activity);GO:0006813(potassium ion transport);GO:0034765(regulation of ion transmembrane transport);GO:0071805(potassium ion transmembrane transport);GO:0005886(plasma membrane);GO:0042995(cell projection);GO:0045121(membrane raft);GO:0030425(dendrite);GO:0005515(protein binding);GO:0043204(perikaryon);GO:0015459(potassium channel regulator activity);GO:0031982(vesicle);GO:0086091(regulation of heart rate by cardiac conduction);GO:0008076(voltage-gated potassium channel complex);GO:0032809(neuronal cell body membrane);GO:1902260(negative regulation of delayed rectifier potassium channel activity);GO:0044325(ion channel binding);GO:0043266(regulation of potassium ion transport);GO:1901387(positive regulation of voltage-gated calcium channel activity);GO:1903765(negative regulation of potassium ion export across plasma membrane);GO:1905025(negative regulation of membrane repolarization during ventricular cardiac muscle cell action potential);GO:1905025(negative regulation of membrane repolarization during ventricular cardiac muscle cell action potential)","04974(Protein digestion and absorption);04974(Protein digestion and absorption)","K04897","NA","potassium voltage-gated channel subfamily E regulatory subunit 3 [Source:HGNC Symbol;Acc:HGNC:6243]",{"v":8.80332081135009,"d":"8.80"},{"v":2.21591284944286,"d":"2.22"},{"v":3.97277393538445,"d":"3.97"},{"v":1.99014670141018,"d":"1.99"},{"v":0.0109560321756266,"d":"0.01"},{"v":0.279631651990225,"d":"0.28"},"up","yes"]
["MSTRG.11031","ATXN7","ENST00000484332;ENST00000474112;ENST00000538065;ENST00000466529;ENST00000474513;MSTRG.11031.4;ENST00000487717;ENST00000472569;ENST00000484668;ENST00000522345;ENST00000477516;ENST00000295900","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0016578(histone deubiquitination);GO:0005730(nucleolus);GO:0015630(microtubule cytoskeleton);GO:0016579(protein deubiquitination);GO:0007601(visual perception);GO:0016363(nuclear matrix);GO:0000226(microtubule cytoskeleton organization);GO:0036459(thiol-dependent ubiquitinyl hydrolase activity);GO:0006997(nucleus organization);GO:0003682(chromatin binding);GO:0042326(negative regulation of phosphorylation);GO:0043569(negative regulation of insulin-like growth factor receptor signaling pathway);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0045944(positive regulation of transcription from RNA polymerase II promoter)","NA","NA","NA","ataxin 7 [Source:HGNC Symbol;Acc:HGNC:10560]",{"v":4.70015754895334,"d":"4.70"},{"v":1.18749334856084,"d":"1.19"},{"v":3.95804957951942,"d":"3.96"},{"v":1.98478968405769,"d":"1.98"},{"v":0.0110117911251092,"d":"0.01"},{"v":0.280326631166714,"d":"0.28"},"up","yes"]
["MSTRG.5565","PDPK2P","ENST00000382326;ENST00000562415;ENST00000571865","NA","NA","NA","NA","3-phosphoinositide dependent protein kinase 2, pseudogene [Source:HGNC Symbol;Acc:HGNC:49897]",{"v":1.41834542092183,"d":"1.42"},{"v":0.346211338680524,"d":"0.35"},{"v":4.09676189788413,"d":"4.10"},{"v":2.03448404641258,"d":"2.03"},{"v":0.0110315396919993,"d":"0.01"},{"v":0.280326631166714,"d":"0.28"},"up","yes"]
["MSTRG.11999","SUB1","ENST00000265073;ENST00000504016;ENST00000502453;ENST00000515355;ENST00000511175;ENST00000510442;ENST00000513013;ENST00000511615;ENST00000506237;ENST00000504789;ENST00000512913;ENST00000511988","GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005730(nucleolus);GO:0003713(transcription coactivator activity);GO:0006355(regulation of transcription, DNA-templated);GO:0006366(transcription from RNA polymerase II promoter);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0070062(extracellular exosome);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0003697(single-stranded DNA binding);GO:0051260(protein homooligomerization);GO:0042802(identical protein binding);GO:0005667(transcription factor complex);GO:0033613(activating transcription factor binding);GO:0003690(double-stranded DNA binding);GO:0060261(positive regulation of transcription initiation from RNA polymerase II promoter);GO:0003678(DNA helicase activity);GO:0032508(DNA duplex unwinding);GO:0001205(transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding);GO:0060395(SMAD protein signal transduction);GO:0060395(SMAD protein signal transduction)","NA","NA","NA","SUB1 homolog, transcriptional regulator [Source:HGNC Symbol;Acc:HGNC:19985]",{"v":4.07296339671815,"d":"4.07"},{"v":11.0487584690047,"d":"11.05"},{"v":0.368635390858087,"d":"0.37"},{"v":-1.43973351126422,"d":"-1.44"},{"v":0.0110749852598808,"d":"0.01"},{"v":0.280816165552391,"d":"0.28"},"down","yes"]
["MSTRG.2146","HBB;HBD","MSTRG.2146.6;MSTRG.2146.7;MSTRG.2146.2;MSTRG.2146.1;MSTRG.2146.5;MSTRG.2146.4;MSTRG.2146.3","NA","NA","NA","NA",null,{"v":125.481526915957,"d":"125.48"},{"v":339.168272976596,"d":"339.17"},{"v":0.369968351740895,"d":"0.37"},{"v":-1.43452623154931,"d":"-1.43"},{"v":0.0111688422763046,"d":"0.01"},{"v":0.28199157915181,"d":"0.28"},"down","yes"]
["MSTRG.12667","TXNDC5;EEF1E1;BLOC1S5;EEF1E1-BLOC1S5;BLOC1S5-TXNDC5","ENST00000379757;ENST00000379715;ENST00000397457;ENST00000475802;ENST00000502429;ENST00000460138;ENST00000397456;ENST00000244777;ENST00000439343;ENST00000469459;ENST00000473453;ENST00000488226;ENST00000507463;ENST00000475998;ENST00000515633;ENST00000429723;ENST00000543936;ENST00000627748","GO:0005783(endoplasmic reticulum);GO:0016853(isomerase activity);GO:0045454(cell redox homeostasis);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0005788(endoplasmic reticulum lumen);GO:0070062(extracellular exosome);GO:0043312(neutrophil degranulation);GO:0043066(negative regulation of apoptotic process);GO:0043202(lysosomal lumen);GO:0035578(azurophil granule lumen);GO:0006457(protein folding);GO:0003756(protein disulfide isomerase activity);GO:0034976(response to endoplasmic reticulum stress);GO:0043277(apoptotic cell clearance);GO:0005623(cell);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0006412(translation);GO:0005730(nucleolus);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0008285(negative regulation of cell proliferation);GO:0043065(positive regulation of apoptotic process);GO:0004364(glutathione transferase activity);GO:0006749(glutathione metabolic process);GO:0006418(tRNA aminoacylation for protein translation);GO:0043517(positive regulation of DNA damage response, signal transduction by p53 class mediator);GO:2000774(positive regulation of cellular senescence);GO:0017101(aminoacyl-tRNA synthetase multienzyme complex);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0043231(intracellular membrane-bounded organelle);GO:1904115(axon cytoplasm);GO:0031083(BLOC-1 complex);GO:0030133(transport vesicle);GO:0008089(anterograde axonal transport);GO:0032438(melanosome organization);GO:0048490(anterograde synaptic vesicle transport);GO:0031175(neuron projection development);GO:0035646(endosome to melanosome transport);GO:0032402(melanosome transport);GO:0050942(positive regulation of pigment cell differentiation);GO:0050942(positive regulation of pigment cell differentiation)","04141(Protein processing in endoplasmic reticulum);04141(Protein processing in endoplasmic reticulum)","K13984","NA","thioredoxin domain containing 5 [Source:HGNC Symbol;Acc:HGNC:21073];eukaryotic translation elongation factor 1 epsilon 1 [Source:HGNC Symbol;Acc:HGNC:3212];biogenesis of lysosomal organelles complex 1 subunit 5 [Source:HGNC Symbol;Acc:HGNC:18561];EEF1E1-BLOC1S5 readthrough (NMD candidate) [Source:HGNC Symbol;Acc:HGNC:49187];BLOC1S5-TXNDC5 readthrough (NMD candidate) [Source:HGNC Symbol;Acc:HGNC:42001]",{"v":3.43777573045163,"d":"3.44"},{"v":9.31651662870833,"d":"9.32"},{"v":0.36899797074996,"d":"0.37"},{"v":-1.43831521246895,"d":"-1.44"},{"v":0.0111699066916243,"d":"0.01"},{"v":0.28199157915181,"d":"0.28"},"down","yes"]
["ENSG00000187017","ESPN","ENST00000377828;ENST00000633239;ENST00000418286;ENST00000434576;ENST00000416731;ENST00000477679;ENST00000636330;ENST00000461727","GO:0003779(actin binding);GO:0051015(actin filament binding);GO:0051017(actin filament bundle assembly);GO:0005737(cytoplasm);GO:0005856(cytoskeleton);GO:0042995(cell projection);GO:0031941(filamentous actin);GO:0032420(stereocilium);GO:0007605(sensory perception of sound);GO:0005902(microvillus);GO:0017124(SH3 domain binding);GO:0007626(locomotory behavior);GO:0030046(parallel actin filament bundle assembly);GO:0051491(positive regulation of filopodium assembly);GO:0051494(negative regulation of cytoskeleton organization);GO:0005903(brush border);GO:0015629(actin cytoskeleton);GO:0032421(stereocilium bundle);GO:0032426(stereocilium tip);GO:0032426(stereocilium tip)","NA","NA","NA","espin [Source:HGNC Symbol;Acc:HGNC:13281]",{"v":2.36465947076613,"d":"2.36"},{"v":0.59546059735023,"d":"0.60"},{"v":3.97114348336187,"d":"3.97"},{"v":1.98955448853675,"d":"1.99"},{"v":0.0113314828957925,"d":"0.01"},{"v":0.284927090700494,"d":"0.28"},"up","yes"]
["MSTRG.14125","GIMAP4","ENST00000255945;ENST00000461940;ENST00000479232;ENST00000478135","GO:0005737(cytoplasm);GO:0005525(GTP binding);GO:0000166(nucleotide binding);GO:0005829(cytosol);GO:0005829(cytosol)","NA","NA","NA","GTPase, IMAP family member 4 [Source:HGNC Symbol;Acc:HGNC:21872]",{"v":44.6412195125399,"d":"44.64"},{"v":120.280183613315,"d":"120.28"},{"v":0.371143592996628,"d":"0.37"},{"v":-1.42995063088661,"d":"-1.43"},{"v":0.0113895184524472,"d":"0.01"},{"v":0.284927090700494,"d":"0.28"},"down","yes"]
["ENSG00000141664","ZCCHC2","ENST00000585873;ENST00000269499;ENST00000621048;ENST00000586834;ENST00000591145;ENST00000591632;ENST00000587612;ENST00000585949;ENST00000591435;ENST00000588676;ENST00000590840","GO:0003676(nucleic acid binding);GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0035091(phosphatidylinositol binding);GO:0005737(cytoplasm);GO:0005737(cytoplasm)","NA","NA","NA","zinc finger CCHC-type containing 2 [Source:HGNC Symbol;Acc:HGNC:22916]",{"v":3.05241439638495,"d":"3.05"},{"v":0.775138467318026,"d":"0.78"},{"v":3.93789564714326,"d":"3.94"},{"v":1.97742488083224,"d":"1.98"},{"v":0.0113919256457634,"d":"0.01"},{"v":0.284927090700494,"d":"0.28"},"up","yes"]
["MSTRG.13529","SNX10","ENST00000338523;ENST00000446848;ENST00000416246;ENST00000396376;ENST00000409838;ENST00000412416;ENST00000409367;ENST00000462993","GO:0035091(phosphatidylinositol binding);GO:0006810(transport);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0015031(protein transport);GO:0005783(endoplasmic reticulum);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0005813(centrosome);GO:0005815(microtubule organizing center);GO:0008289(lipid binding);GO:0005768(endosome);GO:0060271(cilium assembly);GO:0030030(cell projection organization);GO:0010008(endosome membrane);GO:0030316(osteoclast differentiation);GO:0006897(endocytosis);GO:0007032(endosome organization);GO:0051117(ATPase binding);GO:0005545(1-phosphatidylinositol binding);GO:0031313(extrinsic component of endosome membrane);GO:0071539(protein localization to centrosome);GO:0061512(protein localization to cilium);GO:1990830(cellular response to leukemia inhibitory factor);GO:1990830(cellular response to leukemia inhibitory factor)","NA","NA","NA","sorting nexin 10 [Source:HGNC Symbol;Acc:HGNC:14974]",{"v":26.6303591134167,"d":"26.63"},{"v":6.78386261313246,"d":"6.78"},{"v":3.92554516977756,"d":"3.93"},{"v":1.97289302575394,"d":"1.97"},{"v":0.0113973744701575,"d":"0.01"},{"v":0.284927090700494,"d":"0.28"},"up","yes"]
["ENSG00000197136","PCNX3","ENST00000355703;ENST00000530174;ENST00000531280;ENST00000439247;ENST00000531045","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016021(integral component of membrane)","NA","NA","NA","pecanex homolog 3 [Source:HGNC Symbol;Acc:HGNC:18760]",{"v":5.6024860646011,"d":"5.60"},{"v":1.42487521801305,"d":"1.42"},{"v":3.9319134712818,"d":"3.93"},{"v":1.97523157296887,"d":"1.98"},{"v":0.0114088605162946,"d":"0.01"},{"v":0.284927090700494,"d":"0.28"},"up","yes"]
["MSTRG.12760","PPP1R11","ENST00000376772;ENST00000376773;ENST00000376769;MSTRG.12760.2;ENST00000376758;ENST00000376765","GO:0005737(cytoplasm);GO:0005515(protein binding);GO:0004864(protein phosphatase inhibitor activity);GO:0005634(nucleus);GO:0000164(protein phosphatase type 1 complex);GO:0004865(protein serine/threonine phosphatase inhibitor activity);GO:0008157(protein phosphatase 1 binding);GO:0032515(negative regulation of phosphoprotein phosphatase activity);GO:0032515(negative regulation of phosphoprotein phosphatase activity)","NA","NA","NA","protein phosphatase 1 regulatory inhibitor subunit 11 [Source:HGNC Symbol;Acc:HGNC:9285]",{"v":12.8186429764798,"d":"12.82"},{"v":3.25457856801254,"d":"3.25"},{"v":3.93864910881771,"d":"3.94"},{"v":1.97770089409903,"d":"1.98"},{"v":0.0114374721533309,"d":"0.01"},{"v":0.285028678361871,"d":"0.29"},"up","yes"]
["MSTRG.8827","MOB1A","ENST00000396049;ENST00000495286;ENST00000497054;ENST00000488006;ENST00000494600;ENST00000463975","GO:0046872(metal ion binding);GO:0005634(nucleus);GO:0005730(nucleolus);GO:0005829(cytosol);GO:0005515(protein binding);GO:0070062(extracellular exosome);GO:0035329(hippo signaling);GO:0035329(hippo signaling)","04390(Hippo signaling pathway);04392(Hippo signaling pathway - multiple species);04392(Hippo signaling pathway - multiple species)","K06685","NA","MOB kinase activator 1A [Source:HGNC Symbol;Acc:HGNC:16015]",{"v":10.3112289152174,"d":"10.31"},{"v":27.7385755549689,"d":"27.74"},{"v":0.37172885445339,"d":"0.37"},{"v":-1.42767741701555,"d":"-1.43"},{"v":0.0115092332269329,"d":"0.01"},{"v":0.286202838253474,"d":"0.29"},"down","yes"]
["MSTRG.5540","PKD1","ENST00000262304;ENST00000562297;ENST00000485120;ENST00000423118;ENST00000566784;ENST00000564313;ENST00000483024;ENST00000483731;ENST00000480227;ENST00000483814;ENST00000496574;ENST00000564890;ENST00000474088;ENST00000568796;ENST00000564865;ENST00000471603;ENST00000567355;ENST00000486339;ENST00000472659;ENST00000569983","GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0005737(cytoplasm);GO:0005634(nucleus);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0030246(carbohydrate binding);GO:0005886(plasma membrane);GO:0042995(cell projection);GO:0005515(protein binding);GO:0001822(kidney development);GO:0005929(cilium);GO:0070062(extracellular exosome);GO:0019901(protein kinase binding);GO:0007507(heart development);GO:0019904(protein domain specific binding);GO:0005887(integral component of plasma membrane);GO:0044325(ion channel binding);GO:0051216(cartilage development);GO:0000139(Golgi membrane);GO:0009653(anatomical structure morphogenesis);GO:0021510(spinal cord development);GO:0032092(positive regulation of protein binding);GO:0018105(peptidyl-serine phosphorylation);GO:0050982(detection of mechanical stimulus);GO:0048754(branching morphogenesis of an epithelial tube);GO:0007160(cell-matrix adhesion);GO:0007156(homophilic cell adhesion via plasma membrane adhesion molecules);GO:0005262(calcium channel activity);GO:0031514(motile cilium);GO:0021915(neural tube development);GO:0072177(mesonephric duct development);GO:0031659(positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle);GO:0016323(basolateral plasma membrane);GO:0007050(cell cycle arrest);GO:0006611(protein export from nucleus);GO:0007259(JAK-STAT cascade);GO:0043588(skin development);GO:0030660(Golgi-associated vesicle membrane);GO:0060170(ciliary membrane);GO:0061136(regulation of proteasomal protein catabolic process);GO:0001701(in utero embryonic development);GO:0048565(digestive tract development);GO:0072205(metanephric collecting duct development);GO:0070588(calcium ion transmembrane transport);GO:0072218(metanephric ascending thin limb development);GO:0060674(placenta blood vessel development);GO:0060428(lung epithelium development);GO:0001502(cartilage condensation);GO:0001568(blood vessel development);GO:0001889(liver development);GO:0001892(embryonic placenta development);GO:0006807(nitrogen compound metabolic process);GO:0006816(calcium ion transport);GO:0007161(calcium-independent cell-matrix adhesion);GO:0007204(positive regulation of cytosolic calcium ion concentration);GO:0016337(single organismal cell-cell adhesion);GO:0030010(establishment of cell polarity);GO:0030155(regulation of cell adhesion);GO:0034405(response to fluid shear stress);GO:0036303(lymph vessel morphogenesis);GO:0042994(cytoplasmic sequestering of transcription factor);GO:0048806(genitalia development);GO:0060236(regulation of mitotic spindle organization);GO:0072001(renal system development);GO:0072164(mesonephric tubule development);GO:0072237(metanephric proximal tubule development);GO:0072287(metanephric distal tubule morphogenesis);GO:0002133(polycystin complex);GO:0005794(Golgi apparatus);GO:0009986(cell surface);GO:0016328(lateral plasma membrane);GO:0016328(lateral plasma membrane)","NA","NA","NA","polycystin 1, transient receptor potential channel interacting [Source:HGNC Symbol;Acc:HGNC:9008]",{"v":1.7863718255589,"d":"1.79"},{"v":0.453881514187446,"d":"0.45"},{"v":3.93576686804908,"d":"3.94"},{"v":1.9766447663401,"d":"1.98"},{"v":0.0115974430495638,"d":"0.01"},{"v":0.287780141313214,"d":"0.29"},"up","yes"]
["ENSG00000164048","ZNF589","ENST00000457782;ENST00000354698;ENST00000412564;ENST00000440261;ENST00000448461;ENST00000454212","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0005654(nucleoplasm);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0005622(intracellular);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0000977(RNA polymerase II regulatory region sequence-specific DNA binding);GO:0001227(transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding);GO:0001227(transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding)","NA","NA","NA","zinc finger protein 589 [Source:HGNC Symbol;Acc:HGNC:16747]",{"v":0.425611301213548,"d":"0.43"},{"v":1.17428183463141,"d":"1.17"},{"v":0.36244391138618,"d":"0.36"},{"v":-1.46417034121033,"d":"-1.46"},{"v":0.0116462188324012,"d":"0.01"},{"v":0.288341778952358,"d":"0.29"},"down","yes"]
["MSTRG.9132","R3HDM1","ENST00000409478;ENST00000480793;ENST00000441871;ENST00000264160;ENST00000487294;ENST00000429703;ENST00000436436;ENST00000463230;ENST00000445855;ENST00000425804;ENST00000456040;ENST00000483065","GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0003723(RNA binding)","NA","NA","NA","R3H domain containing 1 [Source:HGNC Symbol;Acc:HGNC:9757]",{"v":2.49058114547987,"d":"2.49"},{"v":0.627176411116738,"d":"0.63"},{"v":3.97110143387758,"d":"3.97"},{"v":1.98953921210468,"d":"1.99"},{"v":0.0116697353059165,"d":"0.01"},{"v":0.288341778952358,"d":"0.29"},"up","yes"]
["ENSG00000198824","CHAMP1","ENST00000361283;ENST00000478022;ENST00000463003","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0005654(nucleoplasm);GO:0005694(chromosome);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0016604(nuclear body);GO:0005819(spindle);GO:0000775(chromosome, centromeric region);GO:0000776(kinetochore);GO:0000777(condensed chromosome kinetochore);GO:0051315(attachment of mitotic spindle microtubules to kinetochore);GO:0035372(protein localization to microtubule);GO:0034501(protein localization to kinetochore);GO:0000793(condensed chromosome);GO:0031134(sister chromatid biorientation);GO:0031134(sister chromatid biorientation)","NA","NA","NA","chromosome alignment maintaining phosphoprotein 1 [Source:HGNC Symbol;Acc:HGNC:20311]",{"v":3.85792474562455,"d":"3.86"},{"v":0.97990553080796,"d":"0.98"},{"v":3.93703742282542,"d":"3.94"},{"v":1.97711042584927,"d":"1.98"},{"v":0.0117124696610839,"d":"0.01"},{"v":0.288441065033214,"d":"0.29"},"up","yes"]
["MSTRG.9885","GID8","ENST00000266069;ENST00000497101","GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0030054(cell junction);GO:0005515(protein binding);GO:0005515(protein binding)","NA","NA","NA","GID complex subunit 8 homolog [Source:HGNC Symbol;Acc:HGNC:15857]",{"v":2.91183035677196,"d":"2.91"},{"v":7.83132284011251,"d":"7.83"},{"v":0.371818454713345,"d":"0.37"},{"v":-1.42732971660771,"d":"-1.43"},{"v":0.0117358876462555,"d":"0.01"},{"v":0.288441065033214,"d":"0.29"},"down","yes"]
["MSTRG.7859","PRDX2","ENST00000301522;ENST00000477555;ENST00000498785;ENST00000478908;ENST00000334482;ENST00000466174","GO:0005623(cell);GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0045454(cell redox homeostasis);GO:0016209(antioxidant activity);GO:0008379(thioredoxin peroxidase activity);GO:0019430(removal of superoxide radicals);GO:0005737(cytoplasm);GO:0004601(peroxidase activity);GO:0051920(peroxiredoxin activity);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0042981(regulation of apoptotic process);GO:0043066(negative regulation of apoptotic process);GO:0006979(response to oxidative stress);GO:0034599(cellular response to oxidative stress);GO:0042744(hydrogen peroxide catabolic process);GO:0042744(hydrogen peroxide catabolic process)","NA","NA","NA","peroxiredoxin 2 [Source:HGNC Symbol;Acc:HGNC:9353]",{"v":9.65788446153846,"d":"9.66"},{"v":25.9597442737697,"d":"25.96"},{"v":0.372033112487052,"d":"0.37"},{"v":-1.42649706200868,"d":"-1.43"},{"v":0.0117513550275807,"d":"0.01"},{"v":0.288441065033214,"d":"0.29"},"down","yes"]
["MSTRG.15354","TAF1","MSTRG.15354.1","NA","NA","NA","NA",null,{"v":6.86143,"d":"6.86"},{"v":1.733945,"d":"1.73"},{"v":3.95712090060527,"d":"3.96"},{"v":1.98445114416811,"d":"1.98"},{"v":0.0118127654835119,"d":"0.01"},{"v":0.288441065033214,"d":"0.29"},"up","yes"]
["ENSG00000123080","CDKN2C","ENST00000371761;ENST00000262662;ENST00000396148","GO:0008285(negative regulation of cell proliferation);GO:0005737(cytoplasm);GO:0005634(nucleus);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0005515(protein binding);GO:0007049(cell cycle);GO:0005829(cytosol);GO:0019901(protein kinase binding);GO:0030308(negative regulation of cell growth);GO:0007050(cell cycle arrest);GO:0000082(G1/S transition of mitotic cell cycle);GO:0004861(cyclin-dependent protein serine/threonine kinase inhibitor activity);GO:0042326(negative regulation of phosphorylation);GO:0000079(regulation of cyclin-dependent protein serine/threonine kinase activity);GO:0045736(negative regulation of cyclin-dependent protein serine/threonine kinase activity);GO:0048709(oligodendrocyte differentiation);GO:0048709(oligodendrocyte differentiation)","04110(Cell cycle);05202(Transcriptional misregulation in cancers);05166(HTLV-I infection);01522(Endocrine resistance);01522(Endocrine resistance)","K06622","NA","cyclin dependent kinase inhibitor 2C [Source:HGNC Symbol;Acc:HGNC:1789]",{"v":0.412061223628692,"d":"0.41"},{"v":1.16310552983725,"d":"1.16"},{"v":0.354276729890839,"d":"0.35"},{"v":-1.49705138747126,"d":"-1.50"},{"v":0.0118299602495697,"d":"0.01"},{"v":0.288441065033214,"d":"0.29"},"down","yes"]
["ENSG00000187922","LCN10","ENST00000341040;ENST00000494294;ENST00000474369;ENST00000527229;ENST00000529013;ENST00000406721","GO:0006810(transport);GO:0005576(extracellular region);GO:0005576(extracellular region)","NA","NA","NA","lipocalin 10 [Source:HGNC Symbol;Acc:HGNC:20892]",{"v":0.437919711705372,"d":"0.44"},{"v":1.22260509946047,"d":"1.22"},{"v":0.358185739531615,"d":"0.36"},{"v":-1.48122019451648,"d":"-1.48"},{"v":0.0118442415936826,"d":"0.01"},{"v":0.288441065033214,"d":"0.29"},"down","yes"]
["MSTRG.6775","MED1","ENST00000300651;ENST00000394287;ENST00000581334;ENST00000577831;ENST00000584308","GO:0005634(nucleus);GO:0016020(membrane);GO:0005654(nucleoplasm);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0001104(RNA polymerase II transcription cofactor activity);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0016592(mediator complex);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0003713(transcription coactivator activity);GO:0030374(ligand-dependent nuclear receptor transcription coactivator activity);GO:0045893(positive regulation of transcription, DNA-templated);GO:0005730(nucleolus);GO:0006367(transcription initiation from RNA polymerase II promoter);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0001047(core promoter binding);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0010628(positive regulation of gene expression);GO:0030331(estrogen receptor binding);GO:0042974(retinoic acid receptor binding);GO:0003682(chromatin binding);GO:0004872(receptor activity);GO:0043066(negative regulation of apoptotic process);GO:0070371(ERK1 and ERK2 cascade);GO:0008134(transcription factor binding);GO:0051726(regulation of cell cycle);GO:0000981(RNA polymerase II transcription factor activity, sequence-specific DNA binding);GO:0001525(angiogenesis);GO:0045665(negative regulation of neuron differentiation);GO:0003712(transcription cofactor activity);GO:0030518(intracellular steroid hormone receptor signaling pathway);GO:0030521(androgen receptor signaling pathway);GO:0006702(androgen biosynthetic process);GO:0030216(keratinocyte differentiation);GO:0019216(regulation of lipid metabolic process);GO:0035257(nuclear hormone receptor binding);GO:0042809(vitamin D receptor binding);GO:0071364(cellular response to epidermal growth factor stimulus);GO:0002088(lens development in camera-type eye);GO:0045618(positive regulation of keratinocyte differentiation);GO:0046966(thyroid hormone receptor binding);GO:0016922(ligand-dependent nuclear receptor binding);GO:0071383(cellular response to steroid hormone stimulus);GO:0035855(megakaryocyte development);GO:0097067(cellular response to thyroid hormone stimulus);GO:0000902(cell morphogenesis);GO:0010839(negative regulation of keratinocyte proliferation);GO:0045648(positive regulation of erythrocyte differentiation);GO:0042975(peroxisome proliferator activated receptor binding);GO:0042789(mRNA transcription from RNA polymerase II promoter);GO:0048821(erythrocyte development);GO:0030375(thyroid hormone receptor coactivator activity);GO:0036033(mediator complex binding);GO:0050693(LBD domain binding);GO:0002154(thyroid hormone mediated signaling pathway);GO:0006356(regulation of transcription from RNA polymerase I promoter);GO:0045444(fat cell differentiation);GO:2000273(positive regulation of receptor activity);GO:2001141(regulation of RNA biosynthetic process);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:0031490(chromatin DNA binding);GO:0032403(protein complex binding);GO:0061630(ubiquitin protein ligase activity);GO:0001701(in utero embryonic development);GO:0001889(liver development);GO:0001892(embryonic placenta development);GO:0003222(ventricular trabecula myocardium morphogenesis);GO:0003406(retinal pigment epithelium development);GO:0006590(thyroid hormone generation);GO:0007275(multicellular organism development);GO:0007420(brain development);GO:0007507(heart development);GO:0007595(lactation);GO:0008284(positive regulation of cell proliferation);GO:0009887(animal organ morphogenesis);GO:0016567(protein ubiquitination);GO:0030224(monocyte differentiation);GO:0031100(animal organ regeneration);GO:0033148(positive regulation of intracellular estrogen receptor signaling pathway);GO:0033160(positive regulation of protein import into nucleus, translocation);GO:0033598(mammary gland epithelial cell proliferation);GO:0033601(positive regulation of mammary gland epithelial cell proliferation);GO:0035050(embryonic heart tube development);GO:0035116(embryonic hindlimb morphogenesis);GO:0035162(embryonic hemopoiesis);GO:0035357(peroxisome proliferator activated receptor signaling pathway);GO:0035729(cellular response to hepatocyte growth factor stimulus);GO:0043010(camera-type eye development);GO:0048822(enucleate erythrocyte development);GO:0060335(positive regulation of interferon-gamma-mediated signaling pathway);GO:0060744(mammary gland branching involved in thelarche);GO:0060745(mammary gland branching involved in pregnancy);GO:0060750(epithelial cell proliferation involved in mammary gland duct elongation);GO:0070318(positive regulation of G0 to G1 transition);GO:0070562(regulation of vitamin D receptor signaling pathway);GO:2000347(positive regulation of hepatocyte proliferation);GO:0000151(ubiquitin ligase complex);GO:0000785(chromatin);GO:0032993(protein-DNA complex);GO:0032993(protein-DNA complex)","04919(Thyroid hormone signaling pathway);01522(Endocrine resistance);01522(Endocrine resistance)","K15144","NA","mediator complex subunit 1 [Source:HGNC Symbol;Acc:HGNC:9234]",{"v":3.39869797025921,"d":"3.40"},{"v":0.867711907230559,"d":"0.87"},{"v":3.91685067582707,"d":"3.92"},{"v":1.96969412870985,"d":"1.97"},{"v":0.0118476180160891,"d":"0.01"},{"v":0.288441065033214,"d":"0.29"},"up","yes"]
["MSTRG.13457","TTYH3","ENST00000258796;ENST00000403167;ENST00000407643;ENST00000498454;ENST00000477439;ENST00000400376;ENST00000429448","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0006811(ion transport);GO:0005886(plasma membrane);GO:0005254(chloride channel activity);GO:0006821(chloride transport);GO:0034707(chloride channel complex);GO:1902476(chloride transmembrane transport);GO:0070062(extracellular exosome);GO:0005229(intracellular calcium activated chloride channel activity);GO:0034220(ion transmembrane transport);GO:0034220(ion transmembrane transport)","NA","NA","NA","tweety family member 3 [Source:HGNC Symbol;Acc:HGNC:22222]",{"v":8.54557049534998,"d":"8.55"},{"v":2.19697214537445,"d":"2.20"},{"v":3.88970361474177,"d":"3.89"},{"v":1.95966022980463,"d":"1.96"},{"v":0.0121007349602623,"d":"0.01"},{"v":0.293450405397194,"d":"0.29"},"up","yes"]
["MSTRG.14010","HIPK2","ENST00000428878;ENST00000406875;ENST00000342645","GO:0051091(positive regulation of sequence-specific DNA binding transcription factor activity);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0005515(protein binding);GO:0006974(cellular response to DNA damage stimulus);GO:0006915(apoptotic process);GO:0030218(erythrocyte differentiation);GO:0003714(transcription corepressor activity);GO:0005654(nucleoplasm);GO:0001654(eye development);GO:0045893(positive regulation of transcription, DNA-templated);GO:0030511(positive regulation of transforming growth factor beta receptor signaling pathway);GO:1901796(regulation of signal transduction by p53 class mediator);GO:0051726(regulation of cell cycle);GO:0016605(PML body);GO:0060395(SMAD protein signal transduction);GO:0090575(RNA polymerase II transcription factor complex);GO:0097193(intrinsic apoptotic signaling pathway);GO:0001102(RNA polymerase II activating transcription factor binding);GO:0045766(positive regulation of angiogenesis);GO:0032092(positive regulation of protein binding);GO:0071456(cellular response to hypoxia);GO:0046330(positive regulation of JNK cascade);GO:0018105(peptidyl-serine phosphorylation);GO:0042771(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator);GO:0018107(peptidyl-threonine phosphorylation);GO:0016604(nuclear body);GO:0030514(negative regulation of BMP signaling pathway);GO:0019048(modulation by virus of host morphology or physiology);GO:0046332(SMAD binding);GO:0006978(DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator);GO:0046790(virion binding);GO:0001105(RNA polymerase II transcription coactivator activity);GO:0030578(PML body organization);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0001934(positive regulation of protein phosphorylation);GO:0007179(transforming growth factor beta receptor signaling pathway);GO:0007224(smoothened signaling pathway);GO:0007628(adult walking behavior);GO:0008284(positive regulation of cell proliferation);GO:0008344(adult locomotory behavior);GO:0009952(anterior/posterior pattern specification);GO:0010842(retina layer formation);GO:0030182(neuron differentiation);GO:0043388(positive regulation of DNA binding);GO:0043524(negative regulation of neuron apoptotic process);GO:0048596(embryonic camera-type eye morphogenesis);GO:0050882(voluntary musculoskeletal movement);GO:0060059(embryonic retina morphogenesis in camera-type eye);GO:0060235(lens induction in camera-type eye);GO:0061072(iris morphogenesis);GO:0061072(iris morphogenesis)","04218(Cellular senescence);04218(Cellular senescence)","K08826","EC:2.7.11.1","homeodomain interacting protein kinase 2 [Source:HGNC Symbol;Acc:HGNC:14402]",{"v":4.00807278710557,"d":"4.01"},{"v":1.0321665170757,"d":"1.03"},{"v":3.88316489713415,"d":"3.88"},{"v":1.95723297204848,"d":"1.96"},{"v":0.0121039132166758,"d":"0.01"},{"v":0.293450405397194,"d":"0.29"},"up","yes"]
["MSTRG.6706","AC015911.3","ENST00000592908","NA","NA","NA","NA",null,{"v":4.155158,"d":"4.16"},{"v":1.022999,"d":"1.02"},{"v":4.06174199583773,"d":"4.06"},{"v":2.02209860173474,"d":"2.02"},{"v":0.0122626558937062,"d":"0.01"},{"v":0.295904161846695,"d":"0.30"},"up","yes"]
["MSTRG.4689","DYNC1H1","ENST00000360184;ENST00000554854;ENST00000556499;ENST00000556791;ENST00000555062;ENST00000556139;ENST00000555800;ENST00000556229","GO:0003723(RNA binding);GO:0006810(transport);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0051301(cell division);GO:0003777(microtubule motor activity);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0007049(cell cycle);GO:0005874(microtubule);GO:0003774(motor activity);GO:0007018(microtubule-based movement);GO:0016887(ATPase activity);GO:0005813(centrosome);GO:0030286(dynein complex);GO:0005576(extracellular region);GO:0005868(cytoplasmic dynein complex);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0031122(cytoplasmic microtubule organization);GO:0000086(G2/M transition of mitotic cell cycle);GO:0010389(regulation of G2/M transition of mitotic cell cycle);GO:0097711(ciliary basal body docking);GO:0031012(extracellular matrix);GO:0043312(neutrophil degranulation);GO:0007052(mitotic spindle organization);GO:0007062(sister chromatid cohesion);GO:0019886(antigen processing and presentation of exogenous peptide antigen via MHC class II);GO:0006888(ER to Golgi vesicle-mediated transport);GO:0035578(azurophil granule lumen);GO:0045503(dynein light chain binding);GO:0051959(dynein light intermediate chain binding);GO:0045505(dynein intermediate chain binding);GO:0060236(regulation of mitotic spindle organization);GO:1905832(positive regulation of spindle assembly);GO:0008569(ATP-dependent microtubule motor activity, minus-end-directed);GO:0032388(positive regulation of intracellular transport);GO:0033962(cytoplasmic mRNA processing body assembly);GO:0034063(stress granule assembly);GO:0051293(establishment of spindle localization);GO:0072382(minus-end-directed vesicle transport along microtubule);GO:0090235(regulation of metaphase plate congression);GO:0030175(filopodium);GO:0030175(filopodium)","04145(Phagosome);04962(Vasopressin-regulated water reabsorption);05132(Salmonella infection);05132(Salmonella infection)","K10413","NA","dynein cytoplasmic 1 heavy chain 1 [Source:HGNC Symbol;Acc:HGNC:2961]",{"v":10.8105580437255,"d":"10.81"},{"v":2.797072989195,"d":"2.80"},{"v":3.86495385908281,"d":"3.86"},{"v":1.95045119094967,"d":"1.95"},{"v":0.0123173867753631,"d":"0.01"},{"v":0.295904161846695,"d":"0.30"},"up","yes"]
["MSTRG.22","AL627309.5","ENST00000466557;ENST00000484859;ENST00000490997;ENST00000491962","NA","NA","NA","NA",null,{"v":1.52093888603713,"d":"1.52"},{"v":0.385431305569007,"d":"0.39"},{"v":3.94606993272586,"d":"3.95"},{"v":1.98041652390303,"d":"1.98"},{"v":0.0123276746642698,"d":"0.01"},{"v":0.295904161846695,"d":"0.30"},"up","yes"]
["ENSG00000186566","GPATCH8","ENST00000591680;ENST00000590041;ENST00000335500;ENST00000586265;ENST00000588554;ENST00000635257","GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0046872(metal ion binding);GO:0005515(protein binding);GO:0008150(biological_process);GO:0005575(cellular_component);GO:0005575(cellular_component)","NA","NA","NA","G-patch domain containing 8 [Source:HGNC Symbol;Acc:HGNC:29066]",{"v":0.994101263920279,"d":"0.99"},{"v":0.250500147524142,"d":"0.25"},{"v":3.9684657823384,"d":"3.97"},{"v":1.9885813660556,"d":"1.99"},{"v":0.0123490798829756,"d":"0.01"},{"v":0.295904161846695,"d":"0.30"},"up","yes"]
["MSTRG.11708","AFF1","ENST00000544085;ENST00000395146;ENST00000507468;ENST00000504956;ENST00000511996;ENST00000511442;ENST00000503477;ENST00000307808;ENST00000503369","GO:0005634(nucleus);GO:0005515(protein binding);GO:0006355(regulation of transcription, DNA-templated);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0008023(transcription elongation factor complex);GO:0008023(transcription elongation factor complex)","05202(Transcriptional misregulation in cancers);05202(Transcriptional misregulation in cancers)","K15184","NA","AF4/FMR2 family member 1 [Source:HGNC Symbol;Acc:HGNC:7135]",{"v":5.3312169359918,"d":"5.33"},{"v":1.37557476353303,"d":"1.38"},{"v":3.87562862980932,"d":"3.88"},{"v":1.95443033556181,"d":"1.95"},{"v":0.0123544475671748,"d":"0.01"},{"v":0.295904161846695,"d":"0.30"},"up","yes"]
["ENSG00000237489","LINC00959","ENST00000456581;ENST00000637128","NA","NA","NA","NA","long intergenic non-protein coding RNA 959 [Source:HGNC Symbol;Acc:HGNC:48677]",{"v":0.305813609858732,"d":"0.31"},{"v":0.854178832581906,"d":"0.85"},{"v":0.358020590295309,"d":"0.36"},{"v":-1.48188553347964,"d":"-1.48"},{"v":0.0124316739623566,"d":"0.01"},{"v":0.295904161846695,"d":"0.30"},"down","yes"]
["MSTRG.4168","ZNF219","ENST00000360947;ENST00000451119;ENST00000554923;ENST00000624093;ENST00000553296;ENST00000556944","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0016021(integral component of membrane);GO:0046872(metal ion binding);GO:0007186(G-protein coupled receptor signaling pathway);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0005515(protein binding);GO:0004969(histamine receptor activity);GO:0001505(regulation of neurotransmitter levels);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:0001078(transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0007165(signal transduction);GO:0007275(multicellular organism development);GO:0045892(negative regulation of transcription, DNA-templated);GO:0045892(negative regulation of transcription, DNA-templated)","NA","NA","NA","zinc finger protein 219 [Source:HGNC Symbol;Acc:HGNC:13011]",{"v":0.478614713579877,"d":"0.48"},{"v":0.115880476718072,"d":"0.12"},{"v":4.13024460318979,"d":"4.13"},{"v":2.04622722410459,"d":"2.05"},{"v":0.0124332108708036,"d":"0.01"},{"v":0.295904161846695,"d":"0.30"},"up","yes"]
["MSTRG.2818","AP002004.1","ENST00000528437;ENST00000530264;ENST00000532441;ENST00000531371;ENST00000527637;ENST00000527617;ENST00000532510;ENST00000531091;ENST00000534659","NA","NA","NA","NA",null,{"v":0.444788967494776,"d":"0.44"},{"v":1.23051550615277,"d":"1.23"},{"v":0.361465552665335,"d":"0.36"},{"v":-1.46806992867046,"d":"-1.47"},{"v":0.0124382825650201,"d":"0.01"},{"v":0.295904161846695,"d":"0.30"},"down","yes"]
["MSTRG.8133","MED29","ENST00000615911;ENST00000315588;ENST00000599213;ENST00000594368;ENST00000596297;ENST00000600973","GO:0005654(nucleoplasm);GO:0016592(mediator complex);GO:0005634(nucleus);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0005515(protein binding);GO:0005515(protein binding)","NA","NA","NA","mediator complex subunit 29 [Source:HGNC Symbol;Acc:HGNC:23074]",{"v":7.34004223911343,"d":"7.34"},{"v":1.88447737131682,"d":"1.88"},{"v":3.89500152712601,"d":"3.90"},{"v":1.96162389392923,"d":"1.96"},{"v":0.0124423261564074,"d":"0.01"},{"v":0.295904161846695,"d":"0.30"},"up","yes"]
["MSTRG.9001","TXNDC9","ENST00000264255;ENST00000463385;ENST00000409705;ENST00000438680;ENST00000409434","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0045454(cell redox homeostasis);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0005815(microtubule organizing center);GO:0030496(midbody);GO:0008150(biological_process);GO:0005575(cellular_component);GO:0045296(cadherin binding);GO:0008479(queuine tRNA-ribosyltransferase activity);GO:0008616(queuosine biosynthetic process);GO:0005813(centrosome);GO:0005813(centrosome)","NA","NA","NA","thioredoxin domain containing 9 [Source:HGNC Symbol;Acc:HGNC:24110]",{"v":2.94791645987216,"d":"2.95"},{"v":7.88074971910511,"d":"7.88"},{"v":0.374065484242647,"d":"0.37"},{"v":-1.418637243164,"d":"-1.42"},{"v":0.0124777123867457,"d":"0.01"},{"v":0.295904161846695,"d":"0.30"},"down","yes"]
["MSTRG.12660","SSR1;CAGE1","ENST00000244763;ENST00000479365;ENST00000397511;ENST00000479485;ENST00000474597;ENST00000502583;ENST00000489567;ENST00000488834","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005515(protein binding);GO:0036498(IRE1-mediated unfolded protein response);GO:0008284(positive regulation of cell proliferation);GO:0006613(cotranslational protein targeting to membrane);GO:0006613(cotranslational protein targeting to membrane)","04141(Protein processing in endoplasmic reticulum);04141(Protein processing in endoplasmic reticulum)","K13249","NA","signal sequence receptor subunit 1 [Source:HGNC Symbol;Acc:HGNC:11323];cancer antigen 1 [Source:HGNC Symbol;Acc:HGNC:21622]",{"v":7.31642659248242,"d":"7.32"},{"v":1.89595399776906,"d":"1.90"},{"v":3.85896841436635,"d":"3.86"},{"v":1.94821523547712,"d":"1.95"},{"v":0.0125208607462684,"d":"0.01"},{"v":0.295904161846695,"d":"0.30"},"up","yes"]
["MSTRG.7615","KLF16","ENST00000250916;ENST00000592313;ENST00000541015","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:0001078(transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0007212(dopamine receptor signaling pathway);GO:0007212(dopamine receptor signaling pathway)","NA","NA","NA","Kruppel like factor 16 [Source:HGNC Symbol;Acc:HGNC:16857]",{"v":6.00546065109983,"d":"6.01"},{"v":1.54555635194585,"d":"1.55"},{"v":3.88563033857612,"d":"3.89"},{"v":1.95814865592312,"d":"1.96"},{"v":0.0125664558635899,"d":"0.01"},{"v":0.295904161846695,"d":"0.30"},"up","yes"]
["MSTRG.15494","TMEM187","ENST00000369982","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0003674(molecular_function);GO:0008150(biological_process);GO:0030133(transport vesicle)","NA","NA","NA","transmembrane protein 187 [Source:HGNC Symbol;Acc:HGNC:13705]",{"v":0.437555343035343,"d":"0.44"},{"v":1.22557532224532,"d":"1.23"},{"v":0.35702036022863,"d":"0.36"},{"v":-1.4859217439851,"d":"-1.49"},{"v":0.0125748555239299,"d":"0.01"},{"v":0.295904161846695,"d":"0.30"},"down","yes"]
["ENSG00000103657","HERC1","ENST00000443617;ENST00000561348;ENST00000560897;ENST00000558324;ENST00000560316;ENST00000558532;ENST00000559715;ENST00000561359;ENST00000559996;ENST00000559886;ENST00000560462","GO:0006810(transport);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0016740(transferase activity);GO:0016567(protein ubiquitination);GO:0005794(Golgi apparatus);GO:0004842(ubiquitin-protein transferase activity);GO:0005829(cytosol);GO:0043547(positive regulation of GTPase activity);GO:0010507(negative regulation of autophagy);GO:0021702(cerebellar Purkinje cell differentiation);GO:0031175(neuron projection development);GO:0050885(neuromuscular process controlling balance);GO:0005085(guanyl-nucleotide exchange factor activity);GO:0005086(ARF guanyl-nucleotide exchange factor activity);GO:0005086(ARF guanyl-nucleotide exchange factor activity)","04120(Ubiquitin mediated proteolysis);04120(Ubiquitin mediated proteolysis)","K10594","EC:2.3.2.26","HECT and RLD domain containing E3 ubiquitin protein ligase family member 1 [Source:HGNC Symbol;Acc:HGNC:4867]",{"v":8.59299666439922,"d":"8.59"},{"v":2.23121071148771,"d":"2.23"},{"v":3.85127080116501,"d":"3.85"},{"v":1.94533456945069,"d":"1.95"},{"v":0.0125838660109213,"d":"0.01"},{"v":0.295904161846695,"d":"0.30"},"up","yes"]
["MSTRG.15059","SETX","ENST00000224140;ENST00000436441;ENST00000477049;ENST00000474172;ENST00000464133","GO:0006302(double-strand break repair);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0005654(nucleoplasm);GO:0016787(hydrolase activity);GO:0004386(helicase activity);GO:0032508(DNA duplex unwinding);GO:0003677(DNA binding);GO:0005694(chromosome);GO:0045171(intercellular bridge);GO:0042995(cell projection);GO:0005515(protein binding);GO:0006281(DNA repair);GO:0006310(DNA recombination);GO:0006974(cellular response to DNA damage stimulus);GO:0016604(nuclear body);GO:0048511(rhythmic process);GO:0007399(nervous system development);GO:0030154(cell differentiation);GO:0005730(nucleolus);GO:0007283(spermatogenesis);GO:0042802(identical protein binding);GO:0000781(chromosome, telomeric region);GO:0030424(axon);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0030426(growth cone);GO:0034599(cellular response to oxidative stress);GO:0043066(negative regulation of apoptotic process);GO:0000165(MAPK cascade);GO:0006396(RNA processing);GO:0071300(cellular response to retinoic acid);GO:0044344(cellular response to fibroblast growth factor stimulus);GO:0006353(DNA-templated transcription, termination);GO:0000228(nuclear chromosome);GO:0008543(fibroblast growth factor receptor signaling pathway);GO:0010976(positive regulation of neuron projection development);GO:0006376(mRNA splice site selection);GO:0033120(positive regulation of RNA splicing);GO:0070301(cellular response to hydrogen peroxide);GO:0003678(DNA helicase activity);GO:0043491(protein kinase B signaling);GO:0001147(transcription termination site sequence-specific DNA binding);GO:0006369(termination of RNA polymerase II transcription);GO:0007623(circadian rhythm);GO:0060566(positive regulation of DNA-templated transcription, termination);GO:2000144(positive regulation of DNA-templated transcription, initiation);GO:2000806(positive regulation of termination of RNA polymerase II transcription, poly(A)-coupled);GO:2000806(positive regulation of termination of RNA polymerase II transcription, poly(A)-coupled)","NA","NA","NA","senataxin [Source:HGNC Symbol;Acc:HGNC:445]",{"v":21.6278198266063,"d":"21.63"},{"v":5.62166561556837,"d":"5.62"},{"v":3.8472263036619,"d":"3.85"},{"v":1.94381869513184,"d":"1.94"},{"v":0.01260701837939,"d":"0.01"},{"v":0.295904161846695,"d":"0.30"},"up","yes"]
["MSTRG.12459","NDST1","MSTRG.12459.4;ENST00000523767;ENST00000518299;ENST00000522491;ENST00000261797;MSTRG.12459.1;ENST00000521752","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016787(hydrolase activity);GO:0015016([heparan sulfate]-glucosamine N-sulfotransferase activity);GO:0008146(sulfotransferase activity);GO:0016740(transferase activity);GO:0005794(Golgi apparatus);GO:0003824(catalytic activity);GO:0008152(metabolic process);GO:0000139(Golgi membrane);GO:0006954(inflammatory response);GO:0005515(protein binding);GO:0006024(glycosaminoglycan biosynthetic process);GO:0015012(heparan sulfate proteoglycan biosynthetic process);GO:0030210(heparin biosynthetic process);GO:0042328(heparan sulfate N-acetylglucosaminyltransferase activity);GO:0015014(heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process);GO:0019213(deacetylase activity);GO:0050119(N-acetylglucosamine deacetylase activity);GO:0000165(MAPK cascade);GO:0000271(polysaccharide biosynthetic process);GO:0003279(cardiac septum development);GO:0006477(protein sulfation);GO:0007224(smoothened signaling pathway);GO:0007507(heart development);GO:0007585(respiratory gaseous exchange);GO:0008543(fibroblast growth factor receptor signaling pathway);GO:0009887(animal organ morphogenesis);GO:0030203(glycosaminoglycan metabolic process);GO:0030900(forebrain development);GO:0030901(midbrain development);GO:0035904(aorta development);GO:0048702(embryonic neurocranium morphogenesis);GO:0048703(embryonic viscerocranium morphogenesis);GO:0060976(coronary vasculature development);GO:0060976(coronary vasculature development)","00534(Glycosaminoglycan biosynthesis - heparan sulfate / heparin);00534(Glycosaminoglycan biosynthesis - heparan sulfate / heparin)","K02576","EC:3.1.1.-;EC:2.8.2.-","N-deacetylase and N-sulfotransferase 1 [Source:HGNC Symbol;Acc:HGNC:7680]",{"v":6.14472728994803,"d":"6.14"},{"v":1.59575920723211,"d":"1.60"},{"v":3.85066071503747,"d":"3.85"},{"v":1.94510601165822,"d":"1.95"},{"v":0.0126128097919671,"d":"0.01"},{"v":0.295904161846695,"d":"0.30"},"up","yes"]
["MSTRG.965","S100A8","ENST00000368732;ENST00000368733;ENST00000477801","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0005509(calcium ion binding);GO:0005829(cytosol);GO:0045111(intermediate filament cytoskeleton);GO:0005886(plasma membrane);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0008017(microtubule binding);GO:0006915(apoptotic process);GO:0005615(extracellular space);GO:0006914(autophagy);GO:0002376(immune system process);GO:0045087(innate immune response);GO:0006935(chemotaxis);GO:0006954(inflammatory response);GO:0042742(defense response to bacterium);GO:0050727(regulation of inflammatory response);GO:0001816(cytokine production);GO:0030593(neutrophil chemotaxis);GO:0070062(extracellular exosome);GO:0043312(neutrophil degranulation);GO:0051092(positive regulation of NF-kappaB transcription factor activity);GO:0002224(toll-like receptor signaling pathway);GO:0034774(secretory granule lumen);GO:0019730(antimicrobial humoral response);GO:0050729(positive regulation of inflammatory response);GO:2001244(positive regulation of intrinsic apoptotic signaling pathway);GO:0030307(positive regulation of cell growth);GO:0006919(activation of cysteine-type endopeptidase activity involved in apoptotic process);GO:0051493(regulation of cytoskeleton organization);GO:0032602(chemokine production);GO:0050832(defense response to fungus);GO:0050786(RAGE receptor binding);GO:0035662(Toll-like receptor 4 binding);GO:0050544(arachidonic acid binding);GO:0002523(leukocyte migration involved in inflammatory response);GO:0018119(peptidyl-cysteine S-nitrosylation);GO:0032119(sequestering of zinc ion);GO:0070488(neutrophil aggregation);GO:0002526(acute inflammatory response);GO:0002544(chronic inflammatory response);GO:0002793(positive regulation of peptide secretion);GO:0010043(response to zinc ion);GO:0014002(astrocyte development);GO:0032496(response to lipopolysaccharide);GO:0042060(wound healing);GO:0045471(response to ethanol);GO:0045471(response to ethanol)","04657(IL-17 signaling pathway);04657(IL-17 signaling pathway)","K21127","NA","S100 calcium binding protein A8 [Source:HGNC Symbol;Acc:HGNC:10498]",{"v":283.977635352883,"d":"283.98"},{"v":750.477113983102,"d":"750.48"},{"v":0.378396129691008,"d":"0.38"},{"v":-1.40203076229923,"d":"-1.40"},{"v":0.0126987591983642,"d":"0.01"},{"v":0.29731994066654,"d":"0.30"},"down","yes"]
["MSTRG.8421","LENG8","MSTRG.8421.3;MSTRG.8421.4;ENST00000376514;MSTRG.8421.5;ENST00000326764;ENST00000443957;ENST00000610347;ENST00000421200;ENST00000436479;ENST00000462541;ENST00000616932;ENST00000439657","GO:0005515(protein binding);GO:0005515(protein binding)","NA","NA","NA","leukocyte receptor cluster member 8 [Source:HGNC Symbol;Acc:HGNC:15500]",{"v":13.6699377903849,"d":"13.67"},{"v":3.55459341026434,"d":"3.55"},{"v":3.84571066578563,"d":"3.85"},{"v":1.94325022478434,"d":"1.94"},{"v":0.0127471478094756,"d":"0.01"},{"v":0.297852369238311,"d":"0.30"},"up","yes"]
["ENSG00000163376","KBTBD8","ENST00000417314;ENST00000484414;ENST00000460576;ENST00000460784","GO:0005737(cytoplasm);GO:0005794(Golgi apparatus);GO:0005856(cytoskeleton);GO:0005819(spindle);GO:0004842(ubiquitin-protein transferase activity);GO:0005515(protein binding);GO:0005829(cytosol);GO:0043687(post-translational protein modification);GO:0006417(regulation of translation);GO:0042787(protein ubiquitination involved in ubiquitin-dependent protein catabolic process);GO:0031463(Cul3-RING ubiquitin ligase complex);GO:0006513(protein monoubiquitination);GO:0014029(neural crest formation);GO:0014032(neural crest cell development);GO:0014032(neural crest cell development)","NA","NA","NA","kelch repeat and BTB domain containing 8 [Source:HGNC Symbol;Acc:HGNC:30691]",{"v":0.708401402027027,"d":"0.71"},{"v":1.90151779771959,"d":"1.90"},{"v":0.372545238796388,"d":"0.37"},{"v":-1.42451246978403,"d":"-1.42"},{"v":0.012856840280359,"d":"0.01"},{"v":0.299812221236564,"d":"0.30"},"down","yes"]
["MSTRG.14244","DOCK5","ENST00000276440;ENST00000479547;MSTRG.14244.10;ENST00000481728;ENST00000467709;ENST00000444569;ENST00000487948;ENST00000481100;ENST00000410074;ENST00000478099;ENST00000463457;ENST00000521405","GO:0005622(intracellular);GO:0007264(small GTPase mediated signal transduction);GO:0043547(positive regulation of GTPase activity);GO:0005085(guanyl-nucleotide exchange factor activity);GO:1904754(positive regulation of vascular associated smooth muscle cell migration);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0010634(positive regulation of epithelial cell migration);GO:1900026(positive regulation of substrate adhesion-dependent cell spreading);GO:1904694(negative regulation of vascular smooth muscle contraction);GO:1904694(negative regulation of vascular smooth muscle contraction)","NA","NA","NA","dedicator of cytokinesis 5 [Source:HGNC Symbol;Acc:HGNC:23476]",{"v":9.92166781073165,"d":"9.92"},{"v":2.58816979409199,"d":"2.59"},{"v":3.83346866707888,"d":"3.83"},{"v":1.93865038799946,"d":"1.94"},{"v":0.012887568278058,"d":"0.01"},{"v":0.299926513853882,"d":"0.30"},"up","yes"]
["ENSG00000127252","HRASLS","ENST00000264735","NA","NA","NA","NA","HRAS like suppressor [Source:HGNC Symbol;Acc:HGNC:14922]",{"v":1.06062622925577,"d":"1.06"},{"v":2.90268334816082,"d":"2.90"},{"v":0.365395085181371,"d":"0.37"},{"v":-1.45247086604552,"d":"-1.45"},{"v":0.0129216710052964,"d":"0.01"},{"v":0.300118730769013,"d":"0.30"},"down","yes"]
["MSTRG.11861","RPS3A","ENST00000512797;ENST00000512690;ENST00000274065;ENST00000509736;ENST00000507485;ENST00000507327;ENST00000503002;ENST00000506126;ENST00000505243;ENST00000510993;ENST00000515792;ENST00000515818;ENST00000514682","GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0006412(translation);GO:0006413(translational initiation);GO:0005783(endoplasmic reticulum);GO:0005730(nucleolus);GO:0005829(cytosol);GO:0030529(intracellular ribonucleoprotein complex);GO:0005622(intracellular);GO:0003735(structural constituent of ribosome);GO:0005840(ribosome);GO:0005515(protein binding);GO:0022627(cytosolic small ribosomal subunit);GO:0030154(cell differentiation);GO:0005925(focal adhesion);GO:0005654(nucleoplasm);GO:0070062(extracellular exosome);GO:0031012(extracellular matrix);GO:0002181(cytoplasmic translation);GO:0043066(negative regulation of apoptotic process);GO:0006364(rRNA processing);GO:0000184(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay);GO:0019083(viral transcription);GO:0048027(mRNA 5'-UTR binding);GO:0006614(SRP-dependent cotranslational protein targeting to membrane);GO:0006614(SRP-dependent cotranslational protein targeting to membrane)","03010(Ribosome);03010(Ribosome)","K02984","NA","ribosomal protein S3A [Source:HGNC Symbol;Acc:HGNC:10421]",{"v":217.372565620248,"d":"217.37"},{"v":571.663954630073,"d":"571.66"},{"v":0.380245358938034,"d":"0.38"},{"v":-1.39499745555809,"d":"-1.39"},{"v":0.013055604357796,"d":"0.01"},{"v":0.302624218377415,"d":"0.30"},"down","yes"]
["MSTRG.6470","NCOR1","ENST00000268712;ENST00000582357;ENST00000411510;MSTRG.6470.1;ENST00000585296;MSTRG.6470.4;ENST00000584872;ENST00000395849;ENST00000464381;ENST00000430577;ENST00000579573;ENST00000580617;ENST00000395857;ENST00000395848;ENST00000582565;ENST00000436068;ENST00000466825;ENST00000436828;ENST00000579606;ENST00000580554;ENST00000472189;ENST00000395851;ENST00000603989;ENST00000458113;ENST00000583234","GO:0005634(nucleus);GO:0016020(membrane);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0016569(covalent chromatin modification);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0003714(transcription corepressor activity);GO:0000118(histone deacetylase complex);GO:0005876(spindle microtubule);GO:0046329(negative regulation of JNK cascade);GO:0000790(nuclear chromatin);GO:0006366(transcription from RNA polymerase II promoter);GO:0007623(circadian rhythm);GO:0044212(transcription regulatory region DNA binding);GO:0001102(RNA polymerase II activating transcription factor binding);GO:0042826(histone deacetylase binding);GO:0019216(regulation of lipid metabolic process);GO:0051225(spindle assembly);GO:0017053(transcriptional repressor complex);GO:0035257(nuclear hormone receptor binding);GO:0016580(Sin3 complex);GO:0016922(ligand-dependent nuclear receptor binding);GO:0046966(thyroid hormone receptor binding);GO:0072362(regulation of glycolytic process by negative regulation of transcription from RNA polymerase II promoter);GO:0072368(regulation of lipid transport by negative regulation of transcription from RNA polymerase II promoter);GO:1903799(negative regulation of production of miRNAs involved in gene silencing by miRNA);GO:2000191(regulation of fatty acid transport);GO:2000191(regulation of fatty acid transport)","04919(Thyroid hormone signaling pathway);05202(Transcriptional misregulation in cancers);01522(Endocrine resistance);01522(Endocrine resistance)","K04650","NA","nuclear receptor corepressor 1 [Source:HGNC Symbol;Acc:HGNC:7672]",{"v":10.1117466466465,"d":"10.11"},{"v":2.64355744826699,"d":"2.64"},{"v":3.82505273463051,"d":"3.83"},{"v":1.93547963786162,"d":"1.94"},{"v":0.0131734037203116,"d":"0.01"},{"v":0.303952050200331,"d":"0.30"},"up","yes"]
["ENSG00000270882","HIST2H4A","ENST00000618193;ENST00000578186;ENST00000614272","GO:0005634(nucleus);GO:0003723(RNA binding);GO:0016020(membrane);GO:0003677(DNA binding);GO:0046982(protein heterodimerization activity);GO:0006334(nucleosome assembly);GO:0000786(nucleosome);GO:0005694(chromosome);GO:0005515(protein binding);GO:0006352(DNA-templated transcription, initiation);GO:0005576(extracellular region);GO:0005654(nucleoplasm);GO:0070062(extracellular exosome);GO:0044267(cellular protein metabolic process);GO:1902036(regulation of hematopoietic stem cell differentiation);GO:0043234(protein complex);GO:0000784(nuclear chromosome, telomeric region);GO:0034080(CENP-A containing nucleosome assembly);GO:0031012(extracellular matrix);GO:0045815(positive regulation of gene expression, epigenetic);GO:0019904(protein domain specific binding);GO:0042393(histone binding);GO:1904837(beta-catenin-TCF complex assembly);GO:0045652(regulation of megakaryocyte differentiation);GO:0006335(DNA replication-dependent nucleosome assembly);GO:0006336(DNA replication-independent nucleosome assembly);GO:0000228(nuclear chromosome);GO:0060964(regulation of gene silencing by miRNA);GO:0000183(chromatin silencing at rDNA);GO:0045814(negative regulation of gene expression, epigenetic);GO:0006303(double-strand break repair via nonhomologous end joining);GO:0051290(protein heterotetramerization);GO:0045653(negative regulation of megakaryocyte differentiation);GO:0016233(telomere capping);GO:0032200(telomere organization);GO:0000788(nuclear nucleosome);GO:0000788(nuclear nucleosome)","05203(Viral carcinogenesis);05322(Systemic lupus erythematosus);05034(Alcoholism);05034(Alcoholism)","K11254","NA","histone cluster 2 H4 family member a [Source:HGNC Symbol;Acc:HGNC:4794]",{"v":0.659653664179104,"d":"0.66"},{"v":1.80539847761194,"d":"1.81"},{"v":0.365378431608987,"d":"0.37"},{"v":-1.45253662110025,"d":"-1.45"},{"v":0.0131775657566103,"d":"0.01"},{"v":0.303952050200331,"d":"0.30"},"down","yes"]
["MSTRG.12015","TTC33","ENST00000337702;ENST00000636106;ENST00000503936;ENST00000636863","GO:0005515(protein binding);GO:0005515(protein binding)","NA","NA","NA","tetratricopeptide repeat domain 33 [Source:HGNC Symbol;Acc:HGNC:29959]",{"v":0.535466892830963,"d":"0.54"},{"v":1.42683430098226,"d":"1.43"},{"v":0.375283165299809,"d":"0.38"},{"v":-1.41394852057833,"d":"-1.41"},{"v":0.0131914090502856,"d":"0.01"},{"v":0.303952050200331,"d":"0.30"},"down","yes"]
["MSTRG.15437","ELF4","ENST00000335997;MSTRG.15437.1;ENST00000308167","GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0006355(regulation of transcription, DNA-templated);GO:0006366(transcription from RNA polymerase II promoter);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0000981(RNA polymerase II transcription factor activity, sequence-specific DNA binding);GO:0043565(sequence-specific DNA binding);GO:0016604(nuclear body);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0045893(positive regulation of transcription, DNA-templated);GO:0045087(innate immune response);GO:0001787(natural killer cell proliferation);GO:0001866(NK T cell proliferation);GO:0005515(protein binding);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:0030154(cell differentiation);GO:0016605(PML body);GO:0001077(transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0001077(transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding)","NA","NA","NA","E74 like ETS transcription factor 4 [Source:HGNC Symbol;Acc:HGNC:3319]",{"v":12.866512894986,"d":"12.87"},{"v":3.3683355483871,"d":"3.37"},{"v":3.81984297887039,"d":"3.82"},{"v":1.93351333505135,"d":"1.93"},{"v":0.0132410109502681,"d":"0.01"},{"v":0.304490812208838,"d":"0.30"},"up","yes"]
["MSTRG.10888","PTPN23","ENST00000265562;ENST00000477276;ENST00000456221;ENST00000602307;ENST00000495653","GO:0006810(transport);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0015031(protein transport);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0016787(hydrolase activity);GO:0004725(protein tyrosine phosphatase activity);GO:0016791(phosphatase activity);GO:0006470(protein dephosphorylation);GO:0016311(dephosphorylation);GO:0035335(peptidyl-tyrosine dephosphorylation);GO:0004721(phosphoprotein phosphatase activity);GO:0005856(cytoskeleton);GO:0042995(cell projection);GO:0005515(protein binding);GO:0016604(nuclear body);GO:0031410(cytoplasmic vesicle);GO:0060271(cilium assembly);GO:0030334(regulation of cell migration);GO:0005768(endosome);GO:0005929(cilium);GO:0070062(extracellular exosome);GO:0019901(protein kinase binding);GO:0030030(cell projection organization);GO:0036064(ciliary basal body);GO:0005769(early endosome);GO:0043162(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway);GO:0010633(negative regulation of epithelial cell migration);GO:2000643(positive regulation of early endosome to late endosome transport);GO:0032456(endocytic recycling);GO:0045022(early endosome to late endosome transport);GO:0061357(positive regulation of Wnt protein secretion);GO:1903387(positive regulation of homophilic cell adhesion);GO:1903393(positive regulation of adherens junction organization);GO:1903393(positive regulation of adherens junction organization)","NA","NA","NA","protein tyrosine phosphatase, non-receptor type 23 [Source:HGNC Symbol;Acc:HGNC:14406]",{"v":2.67665059856211,"d":"2.68"},{"v":0.693339355458953,"d":"0.69"},{"v":3.86052021638136,"d":"3.86"},{"v":1.94879526796599,"d":"1.95"},{"v":0.0133053540582844,"d":"0.01"},{"v":0.305365764187464,"d":"0.31"},"up","yes"]
["MSTRG.10248","MIF-AS1","ENST00000406213","NA","NA","NA","NA","MIF antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:27669]",{"v":0.57382,"d":"0.57"},{"v":1.60384,"d":"1.60"},{"v":0.357778830806065,"d":"0.36"},{"v":-1.48286006690115,"d":"-1.48"},{"v":0.0133625170528197,"d":"0.01"},{"v":0.306072801842988,"d":"0.31"},"down","yes"]
["MSTRG.13316","HIVEP2","ENST00000367603;ENST00000367604;ENST00000474532;ENST00000012134","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0005654(nucleoplasm);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0007165(signal transduction);GO:0007275(multicellular organism development);GO:0043565(sequence-specific DNA binding);GO:0044212(transcription regulatory region DNA binding);GO:0006366(transcription from RNA polymerase II promoter);GO:0006366(transcription from RNA polymerase II promoter)","NA","NA","NA","human immunodeficiency virus type I enhancer binding protein 2 [Source:HGNC Symbol;Acc:HGNC:4921]",{"v":8.35405796976222,"d":"8.35"},{"v":2.19417845234975,"d":"2.19"},{"v":3.80737399039529,"d":"3.81"},{"v":1.92879628978148,"d":"1.93"},{"v":0.013435511889597,"d":"0.01"},{"v":0.30705892093516,"d":"0.31"},"up","yes"]
["MSTRG.1019","ADAR","MSTRG.1019.5;ENST00000368471;ENST00000368474;ENST00000529168;MSTRG.1019.1;MSTRG.1019.3;ENST00000471068;ENST00000534279;MSTRG.1019.7;ENST00000494866;ENST00000492630;MSTRG.1019.2;ENST00000526905;ENST00000463920;ENST00000530954","GO:0003723(RNA binding);GO:0006396(RNA processing);GO:0006397(mRNA processing);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0046872(metal ion binding);GO:0005730(nucleolus);GO:0005654(nucleoplasm);GO:0016787(hydrolase activity);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0002376(immune system process);GO:0045087(innate immune response);GO:0031047(gene silencing by RNA);GO:0051607(defense response to virus);GO:0004000(adenosine deaminase activity);GO:0009615(response to virus);GO:0003726(double-stranded RNA adenosine deaminase activity);GO:0060337(type I interferon signaling pathway);GO:0045070(positive regulation of viral genome replication);GO:0044387(negative regulation of protein kinase activity by regulation of protein phosphorylation);GO:0035455(response to interferon-alpha);GO:0044530(supraspliceosomal complex);GO:0001649(osteoblast differentiation);GO:0001701(in utero embryonic development);GO:0002244(hematopoietic progenitor cell differentiation);GO:0002566(somatic diversification of immune receptors via somatic mutation);GO:0006382(adenosine to inosine editing);GO:0016553(base conversion or substitution editing);GO:0030218(erythrocyte differentiation);GO:0031054(pre-miRNA processing);GO:0035196(production of miRNAs involved in gene silencing by miRNA);GO:0035280(miRNA loading onto RISC involved in gene silencing by miRNA);GO:0043066(negative regulation of apoptotic process);GO:0045071(negative regulation of viral genome replication);GO:0060216(definitive hemopoiesis);GO:0060339(negative regulation of type I interferon-mediated signaling pathway);GO:0061484(hematopoietic stem cell homeostasis);GO:0098586(cellular response to virus);GO:1900369(negative regulation of RNA interference);GO:1900369(negative regulation of RNA interference)","04623(Cytosolic DNA-sensing pathway);05162(Measles);05164(Influenza A);05164(Influenza A)","K12968","EC:3.5.4.37","adenosine deaminase, RNA specific [Source:HGNC Symbol;Acc:HGNC:225]",{"v":56.544615661896,"d":"56.54"},{"v":14.8728239276391,"d":"14.87"},{"v":3.80187487843621,"d":"3.80"},{"v":1.92671105296754,"d":"1.93"},{"v":0.0134645469722787,"d":"0.01"},{"v":0.30705892093516,"d":"0.31"},"up","yes"]
["ENSG00000157985","AGAP1","ENST00000409538;ENST00000448025;ENST00000418654;ENST00000428334;ENST00000409457;ENST00000635100;ENST00000614409;ENST00000304032","GO:0006810(transport);GO:0005737(cytoplasm);GO:0015031(protein transport);GO:0005525(GTP binding);GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0003924(GTPase activity);GO:0043547(positive regulation of GTPase activity);GO:0005096(GTPase activator activity);GO:0005543(phospholipid binding);GO:0005543(phospholipid binding)","04144(Endocytosis);04144(Endocytosis)","K12491","NA","ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 [Source:HGNC Symbol;Acc:HGNC:16922]",{"v":0.782297445147376,"d":"0.78"},{"v":0.201849986340762,"d":"0.20"},{"v":3.87563784040444,"d":"3.88"},{"v":1.95443376418342,"d":"1.95"},{"v":0.0134928508057384,"d":"0.01"},{"v":0.30705892093516,"d":"0.31"},"up","yes"]
["MSTRG.8474","RPS5","ENST00000196551;ENST00000596046;ENST00000599909;ENST00000598495;ENST00000598807;ENST00000596314;ENST00000601521;ENST00000599232;ENST00000598098","GO:0003723(RNA binding);GO:0016020(membrane);GO:0006412(translation);GO:0006413(translational initiation);GO:0030529(intracellular ribonucleoprotein complex);GO:0003735(structural constituent of ribosome);GO:0005840(ribosome);GO:0015935(small ribosomal subunit);GO:0022627(cytosolic small ribosomal subunit);GO:0005925(focal adhesion);GO:0019843(rRNA binding);GO:0003729(mRNA binding);GO:0000028(ribosomal small subunit assembly);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0031012(extracellular matrix);GO:0005515(protein binding);GO:0006364(rRNA processing);GO:0000184(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay);GO:0019083(viral transcription);GO:0006614(SRP-dependent cotranslational protein targeting to membrane);GO:0006450(regulation of translational fidelity);GO:0006450(regulation of translational fidelity)","03010(Ribosome);03010(Ribosome)","K02989","NA","ribosomal protein S5 [Source:HGNC Symbol;Acc:HGNC:10426]",{"v":50.9626187033453,"d":"50.96"},{"v":133.264492598286,"d":"133.26"},{"v":0.382417084323936,"d":"0.38"},{"v":-1.38678111832902,"d":"-1.39"},{"v":0.0135113328681535,"d":"0.01"},{"v":0.30705892093516,"d":"0.31"},"down","yes"]
["ENSG00000196150","ZNF250","ENST00000528258;ENST00000528028;ENST00000533221;ENST00000525694;ENST00000533622;ENST00000533543;ENST00000292579;ENST00000417550;ENST00000527049","GO:0003676(nucleic acid binding);GO:0006355(regulation of transcription, DNA-templated);GO:0005622(intracellular);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding)","NA","NA","NA","zinc finger protein 250 [Source:HGNC Symbol;Acc:HGNC:13044]",{"v":0.102265201440805,"d":"0.10"},{"v":0.305786140818268,"d":"0.31"},{"v":0.334433735836257,"d":"0.33"},{"v":-1.58020770898538,"d":"-1.58"},{"v":0.0135662104716977,"d":"0.01"},{"v":0.307646040398831,"d":"0.31"},"down","yes"]
["MSTRG.917","MCL1;ADAMTSL4-AS1","MSTRG.917.5;ENST00000620947;ENST00000369026;ENST00000464132;ENST00000307940;ENST00000615012;ENST00000617352;MSTRG.917.2","GO:0043066(negative regulation of apoptotic process);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0071806(protein transmembrane transport);GO:0005739(mitochondrion);GO:0042981(regulation of apoptotic process);GO:0005829(cytosol);GO:0005515(protein binding);GO:0006915(apoptotic process);GO:0007275(multicellular organism development);GO:0005741(mitochondrial outer membrane);GO:0030154(cell differentiation);GO:0005654(nucleoplasm);GO:0046982(protein heterodimerization activity);GO:0001709(cell fate determination);GO:0042803(protein homodimerization activity);GO:2000811(negative regulation of anoikis);GO:0008630(intrinsic apoptotic signaling pathway in response to DNA damage);GO:0010507(negative regulation of autophagy);GO:0034097(response to cytokine);GO:0019725(cellular homeostasis);GO:2001240(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand);GO:2001020(regulation of response to DNA damage stimulus);GO:0097192(extrinsic apoptotic signaling pathway in absence of ligand);GO:0097136(Bcl-2 family protein complex);GO:0015266(protein channel activity);GO:0051434(BH3 domain binding);GO:0008637(apoptotic mitochondrial changes);GO:1903378(positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway);GO:2001243(negative regulation of intrinsic apoptotic signaling pathway);GO:0005759(mitochondrial matrix);GO:0005759(mitochondrial matrix)","04630(Jak-STAT signaling pathway);04151(PI3K-Akt signaling pathway);04210(Apoptosis);05206(MicroRNAs in cancer);05206(MicroRNAs in cancer)","K02539","NA","MCL1, BCL2 family apoptosis regulator [Source:HGNC Symbol;Acc:HGNC:6943];ADAMTSL4 antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:32041]",{"v":91.0677126784745,"d":"91.07"},{"v":24.0001093806825,"d":"24.00"},{"v":3.79447073486149,"d":"3.79"},{"v":1.92389866786982,"d":"1.92"},{"v":0.0135901505833635,"d":"0.01"},{"v":0.307646040398831,"d":"0.31"},"up","yes"]
["ENSG00000145781","COMMD10","ENST00000632434;ENST00000274458;ENST00000503424;ENST00000506589;ENST00000515539;ENST00000508250","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0005515(protein binding);GO:0005515(protein binding)","NA","NA","NA","COMM domain containing 10 [Source:HGNC Symbol;Acc:HGNC:30201]",{"v":2.27429357467532,"d":"2.27"},{"v":6.00715251582792,"d":"6.01"},{"v":0.378597608215025,"d":"0.38"},{"v":-1.40126279802224,"d":"-1.40"},{"v":0.013722039297484,"d":"0.01"},{"v":0.309047162984005,"d":"0.31"},"down","yes"]
["ENSG00000048707","VPS13D","ENST00000487188;ENST00000011700;ENST00000476045;ENST00000620676;ENST00000489961;ENST00000473099;ENST00000476169;ENST00000466732;ENST00000613099;ENST00000481484;ENST00000543766;ENST00000469054;ENST00000460333","GO:0070062(extracellular exosome);GO:0070062(extracellular exosome)","NA","NA","NA","vacuolar protein sorting 13 homolog D [Source:HGNC Symbol;Acc:HGNC:23595]",{"v":3.5451598824352,"d":"3.55"},{"v":0.932399045947161,"d":"0.93"},{"v":3.80219166658832,"d":"3.80"},{"v":1.92683125935807,"d":"1.93"},{"v":0.0137357976404648,"d":"0.01"},{"v":0.309047162984005,"d":"0.31"},"up","yes"]
["MSTRG.9517","SNED1","ENST00000310397;ENST00000491761;ENST00000469006;ENST00000401644;ENST00000405547","GO:0005509(calcium ion binding);GO:0005576(extracellular region);GO:0007160(cell-matrix adhesion);GO:0070062(extracellular exosome);GO:0070062(extracellular exosome)","NA","NA","NA","sushi, nidogen and EGF like domains 1 [Source:HGNC Symbol;Acc:HGNC:24696]",{"v":0.371833608298999,"d":"0.37"},{"v":0.0933753078281342,"d":"0.09"},{"v":3.98214064239973,"d":"3.98"},{"v":1.99354417548068,"d":"1.99"},{"v":0.0137725675188874,"d":"0.01"},{"v":0.309047162984005,"d":"0.31"},"up","yes"]
["ENSG00000134318","ROCK2","ENST00000315872;ENST00000460262","GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0005829(cytosol);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0035556(intracellular signal transduction);GO:0005886(plasma membrane);GO:0030036(actin cytoskeleton organization);GO:0005856(cytoskeleton);GO:0048511(rhythmic process);GO:0005813(centrosome);GO:0005815(microtubule organizing center);GO:0032956(regulation of actin cytoskeleton organization);GO:0006939(smooth muscle contraction);GO:0007266(Rho protein signal transduction);GO:0017048(Rho GTPase binding);GO:0005515(protein binding);GO:2000114(regulation of establishment of cell polarity);GO:0001934(positive regulation of protein phosphorylation);GO:0010628(positive regulation of gene expression);GO:0010825(positive regulation of centrosome duplication);GO:0048013(ephrin receptor signaling pathway);GO:0048010(vascular endothelial growth factor receptor signaling pathway);GO:0005198(structural molecule activity);GO:0016525(negative regulation of angiogenesis);GO:0030155(regulation of cell adhesion);GO:0036464(cytoplasmic ribonucleoprotein granule);GO:0010595(positive regulation of endothelial cell migration);GO:0090002(establishment of protein localization to plasma membrane);GO:0007249(I-kappaB kinase/NF-kappaB signaling);GO:0030866(cortical actin cytoskeleton organization);GO:0035509(negative regulation of myosin-light-chain-phosphatase activity);GO:1903140(regulation of establishment of endothelial barrier);GO:1903347(negative regulation of bicellular tight junction assembly);GO:0039694(viral RNA genome replication);GO:0042752(regulation of circadian rhythm);GO:0051893(regulation of focal adhesion assembly);GO:2000145(regulation of cell motility);GO:0051298(centrosome duplication);GO:0000910(cytokinesis);GO:0072518(Rho-dependent protein serine/threonine kinase activity);GO:0045616(regulation of keratinocyte differentiation);GO:0051492(regulation of stress fiber assembly);GO:0071394(cellular response to testosterone stimulus);GO:0005622(intracellular);GO:0005622(intracellular)","04310(Wnt signaling pathway);04071(Sphingolipid signaling pathway);04024(cAMP signaling pathway);04022(cGMP - PKG signaling pathway);04510(Focal adhesion);04530(Tight junction);04810(Regulation of actin cytoskeleton);04611(Platelet activation);04670(Leukocyte transendothelial migration);04062(Chemokine signaling pathway);04921(Oxytocin signaling pathway);04270(Vascular smooth muscle contraction);04360(Axon guidance);05200(Pathways in cancer);05205(Proteoglycans in cancer);05130(Pathogenic Escherichia coli infection);05132(Salmonella infection);05131(Shigellosis);05131(Shigellosis)","K17388","EC:2.7.11.1","Rho associated coiled-coil containing protein kinase 2 [Source:HGNC Symbol;Acc:HGNC:10252]",{"v":2.42471629472647,"d":"2.42"},{"v":0.635999260719566,"d":"0.64"},{"v":3.81245143584469,"d":"3.81"},{"v":1.93071896019573,"d":"1.93"},{"v":0.0137920718810699,"d":"0.01"},{"v":0.309047162984005,"d":"0.31"},"up","yes"]
["MSTRG.259","LDLRAP1","ENST00000374338;ENST00000474283;ENST00000484476;ENST00000488127;ENST00000485476;ENST00000470950;ENST00000462394","GO:0042632(cholesterol homeostasis);GO:0006810(transport);GO:0005737(cytoplasm);GO:0009967(positive regulation of signal transduction);GO:0006629(lipid metabolic process);GO:0005829(cytosol);GO:0008202(steroid metabolic process);GO:0005515(protein binding);GO:0008203(cholesterol metabolic process);GO:0005886(plasma membrane);GO:0006897(endocytosis);GO:0061024(membrane organization);GO:0005769(early endosome);GO:0009925(basal plasma membrane);GO:0048260(positive regulation of receptor-mediated endocytosis);GO:0009898(cytoplasmic side of plasma membrane);GO:0030424(axon);GO:0030665(clathrin-coated vesicle membrane);GO:0030159(receptor signaling complex scaffold activity);GO:0030276(clathrin binding);GO:0030121(AP-1 adaptor complex);GO:0035615(clathrin adaptor activity);GO:0030122(AP-2 adaptor complex);GO:0001540(amyloid-beta binding);GO:0034383(low-density lipoprotein particle clearance);GO:0090118(receptor-mediated endocytosis involved in cholesterol transport);GO:0055037(recycling endosome);GO:0050750(low-density lipoprotein particle receptor binding);GO:0006898(receptor-mediated endocytosis);GO:1905602(positive regulation of receptor-mediated endocytosis involved in cholesterol transport);GO:0001784(phosphotyrosine residue binding);GO:0090003(regulation of establishment of protein localization to plasma membrane);GO:0005883(neurofilament);GO:0005546(phosphatidylinositol-4,5-bisphosphate binding);GO:0031623(receptor internalization);GO:0043393(regulation of protein binding);GO:0035591(signaling adaptor activity);GO:0035612(AP-2 adaptor complex binding);GO:0042982(amyloid precursor protein metabolic process);GO:0090205(positive regulation of cholesterol metabolic process);GO:0090205(positive regulation of cholesterol metabolic process)","04144(Endocytosis);04979(Cholesterol metabolism);04979(Cholesterol metabolism)","K12474","NA","low density lipoprotein receptor adaptor protein 1 [Source:HGNC Symbol;Acc:HGNC:18640]",{"v":15.1210613109135,"d":"15.12"},{"v":3.98004306596257,"d":"3.98"},{"v":3.79922052608657,"d":"3.80"},{"v":1.92570345579281,"d":"1.93"},{"v":0.0138021080088685,"d":"0.01"},{"v":0.309047162984005,"d":"0.31"},"up","yes"]
["MSTRG.3982","ZC3H13","ENST00000242848;ENST00000282007;ENST00000428921;ENST00000464597;ENST00000470308","GO:0003723(RNA binding);GO:0005634(nucleus);GO:0016607(nuclear speck);GO:0046872(metal ion binding);GO:0005515(protein binding);GO:0005654(nucleoplasm);GO:0005654(nucleoplasm)","NA","NA","NA","zinc finger CCCH-type containing 13 [Source:HGNC Symbol;Acc:HGNC:20368]",{"v":6.77021774651729,"d":"6.77"},{"v":1.78415572401364,"d":"1.78"},{"v":3.79463387382296,"d":"3.79"},{"v":1.92396069357189,"d":"1.92"},{"v":0.0138188039117,"d":"0.01"},{"v":0.309047162984005,"d":"0.31"},"up","yes"]
["MSTRG.1073","PMF1;BGLAP;PMF1-BGLAP","ENST00000368277;ENST00000368279;ENST00000368272;ENST00000490491;ENST00000606952;ENST00000471413;ENST00000466489;ENST00000497069;ENST00000368276;ENST00000368273;ENST00000567140","GO:0005634(nucleus);GO:0005794(Golgi apparatus);GO:0043231(intracellular membrane-bounded organelle);GO:0005654(nucleoplasm);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0051301(cell division);GO:0005694(chromosome);GO:0005515(protein binding);GO:0007049(cell cycle);GO:0003713(transcription coactivator activity);GO:0007059(chromosome segregation);GO:0000775(chromosome, centromeric region);GO:0000776(kinetochore);GO:0000777(condensed chromosome kinetochore);GO:0005829(cytosol);GO:0007062(sister chromatid cohesion);GO:0006366(transcription from RNA polymerase II promoter);GO:0043522(leucine zipper domain binding);GO:0005667(transcription factor complex);GO:0000444(MIS12/MIND type complex);GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0005509(calcium ion binding);GO:0007155(cell adhesion);GO:0005576(extracellular region);GO:0030500(regulation of bone mineralization);GO:0031214(biomineral tissue development);GO:0030282(bone mineralization);GO:0005788(endoplasmic reticulum lumen);GO:0001501(skeletal system development);GO:0006888(ER to Golgi vesicle-mediated transport);GO:0005796(Golgi lumen);GO:0005198(structural molecule activity);GO:0033280(response to vitamin D);GO:0006465(signal peptide processing);GO:0017187(peptidyl-glutamic acid carboxylation);GO:0046848(hydroxyapatite binding);GO:0008147(structural constituent of bone);GO:0001503(ossification);GO:0001649(osteoblast differentiation);GO:0002076(osteoblast development);GO:0007568(aging);GO:0007569(cell aging);GO:0009612(response to mechanical stimulus);GO:0009629(response to gravity);GO:0010035(response to inorganic substance);GO:0010043(response to zinc ion);GO:0014070(response to organic cyclic compound);GO:0014823(response to activity);GO:0031667(response to nutrient levels);GO:0032571(response to vitamin K);GO:0033574(response to testosterone);GO:0033594(response to hydroxyisoflavone);GO:0042476(odontogenesis);GO:0042493(response to drug);GO:0043627(response to estrogen);GO:0045124(regulation of bone resorption);GO:0045471(response to ethanol);GO:0045670(regulation of osteoclast differentiation);GO:0051384(response to glucocorticoid);GO:0060348(bone development);GO:0071305(cellular response to vitamin D);GO:0071363(cellular response to growth factor stimulus);GO:0005615(extracellular space);GO:0005791(rough endoplasmic reticulum);GO:0030425(dendrite);GO:0031982(vesicle);GO:0042995(cell projection);GO:0043204(perikaryon);GO:0005654(nucleoplasm)","NA","NA","NA","polyamine modulated factor 1 [Source:HGNC Symbol;Acc:HGNC:9112];bone gamma-carboxyglutamate protein [Source:HGNC Symbol;Acc:HGNC:1043];PMF1-BGLAP readthrough [Source:HGNC Symbol;Acc:HGNC:42953]",{"v":3.09497592470525,"d":"3.09"},{"v":8.11826313102894,"d":"8.12"},{"v":0.381236217002612,"d":"0.38"},{"v":-1.39124291475772,"d":"-1.39"},{"v":0.0138383298675349,"d":"0.01"},{"v":0.309047162984005,"d":"0.31"},"down","yes"]
["MSTRG.5318","TSPAN3","ENST00000267970;ENST00000424443;ENST00000560715;ENST00000559494;ENST00000559373;ENST00000560514;ENST00000561277;ENST00000558745","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005887(integral component of plasma membrane);GO:0003674(molecular_function);GO:0008150(biological_process);GO:0070062(extracellular exosome);GO:0007166(cell surface receptor signaling pathway);GO:0007166(cell surface receptor signaling pathway)","NA","NA","NA","tetraspanin 3 [Source:HGNC Symbol;Acc:HGNC:17752]",{"v":1.48453494098284,"d":"1.48"},{"v":3.88162238702093,"d":"3.88"},{"v":0.382452179260588,"d":"0.38"},{"v":-1.38664872631508,"d":"-1.39"},{"v":0.0139834685437722,"d":"0.01"},{"v":0.310574455984767,"d":"0.31"},"down","yes"]
["MSTRG.3609","NDUFA12","ENST00000327772;ENST00000547157;ENST00000547447;ENST00000550187;ENST00000551991;ENST00000547986;ENST00000552205;ENST00000538372","GO:0016020(membrane);GO:0055114(oxidation-reduction process);GO:0005743(mitochondrial inner membrane);GO:0005739(mitochondrion);GO:0070469(respiratory chain);GO:0008137(NADH dehydrogenase (ubiquinone) activity);GO:0009055(electron carrier activity);GO:0005829(cytosol);GO:0006120(mitochondrial electron transport, NADH to ubiquinone);GO:0006979(response to oxidative stress);GO:0032981(mitochondrial respiratory chain complex I assembly);GO:0005747(mitochondrial respiratory chain complex I);GO:0042775(mitochondrial ATP synthesis coupled electron transport);GO:0007585(respiratory gaseous exchange);GO:0007585(respiratory gaseous exchange)","00190(Oxidative phosphorylation);04723(Retrograde endocannabinoid signaling);05010(Alzheimer's disease);05012(Parkinson's disease);05016(Huntington's disease);04932(Non-alcoholic fatty liver disease (NAFLD));04932(Non-alcoholic fatty liver disease (NAFLD))","K11352","NA","NADH:ubiquinone oxidoreductase subunit A12 [Source:HGNC Symbol;Acc:HGNC:23987]",{"v":2.98465401101928,"d":"2.98"},{"v":7.83110138732782,"d":"7.83"},{"v":0.381128255579605,"d":"0.38"},{"v":-1.39165152616663,"d":"-1.39"},{"v":0.0139913749802624,"d":"0.01"},{"v":0.310574455984767,"d":"0.31"},"down","yes"]
["ENSG00000154237","LRRK1","ENST00000388948;ENST00000534045;ENST00000526457;ENST00000538064;ENST00000525284;ENST00000532145;ENST00000527698;ENST00000531270;ENST00000532029;ENST00000525395;ENST00000525617","GO:0005737(cytoplasm);GO:0005525(GTP binding);GO:0007264(small GTPase mediated signal transduction);GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0005829(cytosol);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0005739(mitochondrion);GO:0005515(protein binding);GO:0042802(identical protein binding);GO:0035556(intracellular signal transduction);GO:0004871(signal transducer activity);GO:0090263(positive regulation of canonical Wnt signaling pathway);GO:0036035(osteoclast development);GO:0045453(bone resorption);GO:0050731(positive regulation of peptidyl-tyrosine phosphorylation);GO:0050732(negative regulation of peptidyl-tyrosine phosphorylation);GO:1902533(positive regulation of intracellular signal transduction);GO:1902533(positive regulation of intracellular signal transduction)","NA","NA","NA","leucine rich repeat kinase 1 [Source:HGNC Symbol;Acc:HGNC:18608]",{"v":0.708446468636364,"d":"0.71"},{"v":0.185602895965909,"d":"0.19"},{"v":3.81700115695657,"d":"3.82"},{"v":1.93243962384329,"d":"1.93"},{"v":0.0139999256470667,"d":"0.01"},{"v":0.310574455984767,"d":"0.31"},"up","yes"]
["ENSG00000170921","TANC2","ENST00000424789;ENST00000580466;ENST00000579541;ENST00000583016;ENST00000389520;ENST00000580068;ENST00000583545","GO:0001701(in utero embryonic development);GO:0001701(in utero embryonic development)","NA","NA","NA","tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 [Source:HGNC Symbol;Acc:HGNC:30212]",{"v":0.83157779847809,"d":"0.83"},{"v":0.217022546750634,"d":"0.22"},{"v":3.8317576257807,"d":"3.83"},{"v":1.93800630764427,"d":"1.94"},{"v":0.0140136928387168,"d":"0.01"},{"v":0.310574455984767,"d":"0.31"},"up","yes"]
["ENSG00000198885","ITPRIPL1","ENST00000420176;ENST00000536814;ENST00000361124;ENST00000439118","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005515(protein binding);GO:0005515(protein binding)","NA","NA","NA","inositol 1,4,5-trisphosphate receptor interacting protein-like 1 [Source:HGNC Symbol;Acc:HGNC:29371]",{"v":0.191727091358555,"d":"0.19"},{"v":0.551354406706793,"d":"0.55"},{"v":0.347738385739455,"d":"0.35"},{"v":-1.52392576449341,"d":"-1.52"},{"v":0.0140460280252947,"d":"0.01"},{"v":0.310664463319759,"d":"0.31"},"down","yes"]
["ENSG00000115568","ZNF142","ENST00000450765;ENST00000432460;ENST00000440934;ENST00000411696;ENST00000450560;ENST00000449707;ENST00000433921","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0003674(molecular_function);GO:0008150(biological_process);GO:0005575(cellular_component);GO:0005575(cellular_component)","NA","NA","NA","zinc finger protein 142 [Source:HGNC Symbol;Acc:HGNC:12927]",{"v":2.9106672274807,"d":"2.91"},{"v":0.762771541178153,"d":"0.76"},{"v":3.8159095749495,"d":"3.82"},{"v":1.93202698441533,"d":"1.93"},{"v":0.0140712570142248,"d":"0.01"},{"v":0.310664463319759,"d":"0.31"},"up","yes"]
["MSTRG.4525","YLPM1","ENST00000325680;ENST00000550021;ENST00000546901;ENST00000553381;ENST00000552421;ENST00000549197;ENST00000547879;ENST00000554107;ENST00000549293","GO:0005634(nucleus);GO:0003723(RNA binding);GO:0016607(nuclear speck);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0005515(protein binding);GO:0008150(biological_process);GO:0008150(biological_process)","NA","NA","NA","YLP motif containing 1 [Source:HGNC Symbol;Acc:HGNC:17798]",{"v":2.76984609451466,"d":"2.77"},{"v":0.729687228757731,"d":"0.73"},{"v":3.79593610159552,"d":"3.80"},{"v":1.92445570714112,"d":"1.92"},{"v":0.0141370504644819,"d":"0.01"},{"v":0.311524795149958,"d":"0.31"},"up","yes"]
["MSTRG.9097","UGGT1","ENST00000259253;MSTRG.9097.5;ENST00000465836;ENST00000438277;ENST00000430075;ENST00000488439;ENST00000376723","GO:0006486(protein glycosylation);GO:0003980(UDP-glucose:glycoprotein glucosyltransferase activity);GO:0097359(UDP-glucosylation);GO:0016740(transferase activity);GO:0016757(transferase activity, transferring glycosyl groups);GO:0005783(endoplasmic reticulum);GO:0044322(endoplasmic reticulum quality control compartment);GO:0005788(endoplasmic reticulum lumen);GO:0005515(protein binding);GO:0070062(extracellular exosome);GO:0043234(protein complex);GO:1904380(endoplasmic reticulum mannose trimming);GO:0051082(unfolded protein binding);GO:0005793(endoplasmic reticulum-Golgi intermediate compartment);GO:0051084('de novo' posttranslational protein folding);GO:0018279(protein N-linked glycosylation via asparagine);GO:0030968(endoplasmic reticulum unfolded protein response);GO:0071712(ER-associated misfolded protein catabolic process);GO:0071712(ER-associated misfolded protein catabolic process)","04141(Protein processing in endoplasmic reticulum);04141(Protein processing in endoplasmic reticulum)","K11718","EC:2.4.1.-","UDP-glucose glycoprotein glucosyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:15663]",{"v":5.9268324023262,"d":"5.93"},{"v":1.57033906767116,"d":"1.57"},{"v":3.77423737608197,"d":"3.77"},{"v":1.9161851623466,"d":"1.92"},{"v":0.0142521873387279,"d":"0.01"},{"v":0.312989270591772,"d":"0.31"},"up","yes"]
["MSTRG.6161","CMIP","ENST00000537098;ENST00000623842;ENST00000621537;ENST00000569146;ENST00000565029;ENST00000539778;ENST00000398040;ENST00000564666;ENST00000561605;ENST00000565680;ENST00000566513;ENST00000566462","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0005515(protein binding);GO:0005515(protein binding)","NA","NA","NA","c-Maf inducing protein [Source:HGNC Symbol;Acc:HGNC:24319]",{"v":8.20626879339363,"d":"8.21"},{"v":2.17456079992135,"d":"2.17"},{"v":3.77375918562058,"d":"3.77"},{"v":1.91600236337405,"d":"1.92"},{"v":0.0142574118783301,"d":"0.01"},{"v":0.312989270591772,"d":"0.31"},"up","yes"]
["MSTRG.14903","PTBP3","ENST00000374257;MSTRG.14903.5;ENST00000343327;ENST00000334318;MSTRG.14903.3;ENST00000487997;ENST00000458258;ENST00000374255;ENST00000450374","GO:0005634(nucleus);GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0006397(mRNA processing);GO:0008380(RNA splicing);GO:0045595(regulation of cell differentiation);GO:0030154(cell differentiation);GO:0043249(erythrocyte maturation);GO:0009653(anatomical structure morphogenesis);GO:0033119(negative regulation of RNA splicing);GO:0033119(negative regulation of RNA splicing)","NA","NA","NA","polypyrimidine tract binding protein 3 [Source:HGNC Symbol;Acc:HGNC:10253]",{"v":24.6739191647073,"d":"24.67"},{"v":6.55754275154527,"d":"6.56"},{"v":3.76267759122012,"d":"3.76"},{"v":1.91175967593909,"d":"1.91"},{"v":0.0143306657392986,"d":"0.01"},{"v":0.313417709603843,"d":"0.31"},"up","yes"]
["MSTRG.3681","FICD","ENST00000552695;ENST00000552758;ENST00000546448;ENST00000361549","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0016740(transferase activity);GO:0016779(nucleotidyltransferase activity);GO:0034260(negative regulation of GTPase activity);GO:0070733(protein adenylyltransferase activity);GO:0018117(protein adenylylation);GO:0018117(protein adenylylation)","NA","NA","NA","FIC domain containing [Source:HGNC Symbol;Acc:HGNC:18416]",{"v":0.18349083993438,"d":"0.18"},{"v":0.51143215725334,"d":"0.51"},{"v":0.358778456403333,"d":"0.36"},{"v":-1.47883483164583,"d":"-1.48"},{"v":0.0143309053474245,"d":"0.01"},{"v":0.313417709603843,"d":"0.31"},"down","yes"]
["MSTRG.7074","AC025048.6","ENST00000634326;ENST00000627667","NA","NA","NA","NA",null,{"v":2.98895,"d":"2.99"},{"v":7.88482187080104,"d":"7.88"},{"v":0.37907641402384,"d":"0.38"},{"v":-1.39943939946929,"d":"-1.40"},{"v":0.0143924555377672,"d":"0.01"},{"v":0.3136461122229,"d":"0.31"},"down","yes"]
["MSTRG.9574","MAVS","ENST00000428216;ENST00000416600","GO:0051091(positive regulation of sequence-specific DNA binding transcription factor activity);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0001934(positive regulation of protein phosphorylation);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005739(mitochondrion);GO:0004871(signal transducer activity);GO:0005515(protein binding);GO:0007165(signal transduction);GO:0005741(mitochondrial outer membrane);GO:0051607(defense response to virus);GO:0002376(immune system process);GO:0045087(innate immune response);GO:0005777(peroxisome);GO:0005778(peroxisomal membrane);GO:0042742(defense response to bacterium);GO:0031966(mitochondrial membrane);GO:0016579(protein deubiquitination);GO:0045071(negative regulation of viral genome replication);GO:0016032(viral process);GO:0043123(positive regulation of I-kappaB kinase/NF-kappaB signaling);GO:1904469(positive regulation of tumor necrosis factor secretion);GO:2000778(positive regulation of interleukin-6 secretion);GO:0032727(positive regulation of interferon-alpha production);GO:0032728(positive regulation of interferon-beta production);GO:0032757(positive regulation of interleukin-8 production);GO:0032760(positive regulation of tumor necrosis factor production);GO:1900063(regulation of peroxisome organization);GO:0019901(protein kinase binding);GO:0002230(positive regulation of defense response to virus by host);GO:0032480(negative regulation of type I interferon production);GO:0071360(cellular response to exogenous dsRNA);GO:0033160(positive regulation of protein import into nucleus, translocation);GO:0035549(positive regulation of interferon-beta secretion);GO:0042993(positive regulation of transcription factor import into nucleus);GO:0060760(positive regulation of response to cytokine stimulus);GO:1902741(positive regulation of interferon-alpha secretion);GO:0060340(positive regulation of type I interferon-mediated signaling pathway);GO:0050700(CARD domain binding);GO:0002218(activation of innate immune response);GO:0032481(positive regulation of type I interferon production);GO:0039529(RIG-I signaling pathway);GO:0071651(positive regulation of chemokine (C-C motif) ligand 5 production);GO:0071660(positive regulation of IP-10 production);GO:0071660(positive regulation of IP-10 production)","04621(NOD-like receptor signaling pathway);04622(RIG-I-like receptor signaling pathway);04623(Cytosolic DNA-sensing pathway);05162(Measles);05164(Influenza A);05161(Hepatitis B);05160(Hepatitis C);05168(Herpes simplex infection);05168(Herpes simplex infection)","K12648","NA","mitochondrial antiviral signaling protein [Source:HGNC Symbol;Acc:HGNC:29233]",{"v":2.09934175957863,"d":"2.10"},{"v":0.554462003228273,"d":"0.55"},{"v":3.78626803524051,"d":"3.79"},{"v":1.92077654506821,"d":"1.92"},{"v":0.014432539883901,"d":"0.01"},{"v":0.3136461122229,"d":"0.31"},"up","yes"]
["MSTRG.8358","SIGLEC9","ENST00000250360;ENST00000440804;ENST00000599948;MSTRG.8358.1","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0030246(carbohydrate binding);GO:0007155(cell adhesion);GO:0050776(regulation of immune response);GO:0005886(plasma membrane);GO:0005887(integral component of plasma membrane);GO:0043312(neutrophil degranulation);GO:0030667(secretory granule membrane);GO:0007166(cell surface receptor signaling pathway);GO:0007166(cell surface receptor signaling pathway)","NA","NA","NA","sialic acid binding Ig like lectin 9 [Source:HGNC Symbol;Acc:HGNC:10878]",{"v":8.00334437539074,"d":"8.00"},{"v":2.12523128815004,"d":"2.13"},{"v":3.76586982321225,"d":"3.77"},{"v":1.91298313042159,"d":"1.91"},{"v":0.0144613973717599,"d":"0.01"},{"v":0.3136461122229,"d":"0.31"},"up","yes"]
["MSTRG.7096","CD79B","ENST00000006750;ENST00000392795;ENST00000349817;ENST00000559358;ENST00000558969;ENST00000583260","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005794(Golgi apparatus);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0004888(transmembrane signaling receptor activity);GO:0007166(cell surface receptor signaling pathway);GO:0002376(immune system process);GO:0002250(adaptive immune response);GO:0050853(B cell receptor signaling pathway);GO:0009897(external side of plasma membrane);GO:0005737(cytoplasm);GO:0070062(extracellular exosome);GO:0005887(integral component of plasma membrane);GO:0006955(immune response);GO:0007165(signal transduction);GO:0042803(protein homodimerization activity);GO:0051260(protein homooligomerization);GO:0030183(B cell differentiation);GO:0019815(B cell receptor complex);GO:0019815(B cell receptor complex)","04662(B cell receptor signaling pathway);04662(B cell receptor signaling pathway)","K06507","NA","CD79b molecule [Source:HGNC Symbol;Acc:HGNC:1699]",{"v":10.6593986663462,"d":"10.66"},{"v":27.5945521846154,"d":"27.59"},{"v":0.386286343588104,"d":"0.39"},{"v":-1.37225742012875,"d":"-1.37"},{"v":0.0145229220162467,"d":"0.01"},{"v":0.3136461122229,"d":"0.31"},"down","yes"]
["ENSG00000185864","NPIPB4","ENST00000415645;ENST00000542133;ENST00000537951;ENST00000614197;ENST00000541674;ENST00000542338;ENST00000541329;ENST00000165086;ENST00000518761;ENST00000539318;ENST00000543660;ENST00000538859;ENST00000529969;ENST00000341400;ENST00000540103;ENST00000543654;ENST00000536041;ENST00000545367;ENST00000543449;ENST00000544693","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005654(nucleoplasm);GO:0005654(nucleoplasm)","NA","NA","NA","nuclear pore complex interacting protein family member B4 [Source:HGNC Symbol;Acc:HGNC:41985]",{"v":1.88173231120545,"d":"1.88"},{"v":0.490499764183713,"d":"0.49"},{"v":3.83635721892144,"d":"3.84"},{"v":1.93973706185036,"d":"1.94"},{"v":0.0145368040702109,"d":"0.01"},{"v":0.3136461122229,"d":"0.31"},"up","yes"]
["MSTRG.11960","MRPL36","ENST00000505059;ENST00000510999;ENST00000505818;ENST00000508987;ENST00000382647","GO:0006412(translation);GO:0005739(mitochondrion);GO:0030529(intracellular ribonucleoprotein complex);GO:0005622(intracellular);GO:0003735(structural constituent of ribosome);GO:0005840(ribosome);GO:0016604(nuclear body);GO:0005743(mitochondrial inner membrane);GO:0070125(mitochondrial translational elongation);GO:0070126(mitochondrial translational termination);GO:0005762(mitochondrial large ribosomal subunit);GO:0005762(mitochondrial large ribosomal subunit)","03010(Ribosome);03010(Ribosome)","K02919","NA","mitochondrial ribosomal protein L36 [Source:HGNC Symbol;Acc:HGNC:14490]",{"v":3.18074869010043,"d":"3.18"},{"v":0.792886639885222,"d":"0.79"},{"v":4.01160585901772,"d":"4.01"},{"v":2.00417986787098,"d":"2.00"},{"v":0.01457173354319,"d":"0.01"},{"v":0.3136461122229,"d":"0.31"},"up","yes"]
["MSTRG.3345","KMT2D;PRKAG1","MSTRG.3345.4;ENST00000548065;ENST00000546531;ENST00000550125;MSTRG.3345.23;ENST00000301067;ENST00000549799;ENST00000552463;ENST00000552657;ENST00000552391;ENST00000549726;ENST00000548857;ENST00000549743;ENST00000547306;ENST00000547125;ENST00000548950;ENST00000552212;ENST00000316299;ENST00000550448;ENST00000548605;ENST00000547610;ENST00000548362;ENST00000547082;ENST00000526209;ENST00000550356;ENST00000552793;ENST00000551121","GO:0016020(membrane);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0006629(lipid metabolic process);GO:0006631(fatty acid metabolic process);GO:0006633(fatty acid biosynthetic process);GO:0005515(protein binding);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0010628(positive regulation of gene expression);GO:0006468(protein phosphorylation);GO:0007165(signal transduction);GO:1901796(regulation of signal transduction by p53 class mediator);GO:0004672(protein kinase activity);GO:0007283(spermatogenesis);GO:0045860(positive regulation of protein kinase activity);GO:0019901(protein kinase binding);GO:0007050(cell cycle arrest);GO:0016241(regulation of macroautophagy);GO:0004679(AMP-activated protein kinase activity);GO:0016236(macroautophagy);GO:0031588(nucleotide-activated protein kinase complex);GO:0016208(AMP binding);GO:0008603(cAMP-dependent protein kinase regulator activity);GO:0004691(cAMP-dependent protein kinase activity);GO:0043531(ADP binding);GO:0006110(regulation of glycolytic process);GO:1902593(single-organism nuclear import);GO:0005634(nucleus);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0046872(metal ion binding);GO:0008168(methyltransferase activity);GO:0016740(transferase activity);GO:0032259(methylation);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0016569(covalent chromatin modification);GO:0003677(DNA binding);GO:0018024(histone-lysine N-methyltransferase activity);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0048477(oogenesis);GO:0008284(positive regulation of cell proliferation);GO:0044212(transcription regulatory region DNA binding);GO:1904837(beta-catenin-TCF complex assembly);GO:0035097(histone methyltransferase complex);GO:0042800(histone methyltransferase activity (H3-K4 specific));GO:0001555(oocyte growth);GO:0006342(chromatin silencing);GO:0033148(positive regulation of intracellular estrogen receptor signaling pathway);GO:0043627(response to estrogen);GO:0045652(regulation of megakaryocyte differentiation);GO:0051568(histone H3-K4 methylation);GO:0044666(MLL3/4 complex);GO:0016310(phosphorylation)","04371(Apelin signaling pathway);04068(FoxO signaling pathway);04152(AMPK signaling pathway);04530(Tight junction);04910(Insulin signaling pathway);04922(Glucagon signaling pathway);04920(Adipocytokine signaling pathway);04921(Oxytocin signaling pathway);04211(Longevity regulating pathway - mammal);04213(Longevity regulating pathway - multiple species);04710(Circadian rhythm);05410(Hypertrophic cardiomyopathy (HCM));04932(Non-alcoholic fatty liver disease (NAFLD));04931(Insulin resistance);00310(Lysine degradation);04931(Insulin resistance)","K07200;K09187","EC:2.1.1.43","protein kinase AMP-activated non-catalytic subunit gamma 1 [Source:HGNC Symbol;Acc:HGNC:9385];lysine methyltransferase 2D [Source:HGNC Symbol;Acc:HGNC:7133]",{"v":7.81372043866836,"d":"7.81"},{"v":2.08090352629067,"d":"2.08"},{"v":3.75496525425029,"d":"3.75"},{"v":1.90879955813829,"d":"1.91"},{"v":0.0145750824009079,"d":"0.01"},{"v":0.3136461122229,"d":"0.31"},"up","yes"]
["MSTRG.13329","UTRN","ENST00000367545;MSTRG.13329.5;MSTRG.13329.7;ENST00000367526;ENST00000455022;ENST00000465299;ENST00000460618;ENST00000421035;ENST00000433557;ENST00000628146;ENST00000432686;ENST00000480333","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0005654(nucleoplasm);GO:0003779(actin binding);GO:0005886(plasma membrane);GO:0005856(cytoskeleton);GO:0030054(cell junction);GO:0045202(synapse);GO:0045211(postsynaptic membrane);GO:0005515(protein binding);GO:0070062(extracellular exosome);GO:0043234(protein complex);GO:0006936(muscle contraction);GO:2000649(regulation of sodium ion transmembrane transporter activity);GO:0001954(positive regulation of cell-matrix adhesion);GO:0019901(protein kinase binding);GO:0007517(muscle organ development);GO:0005178(integrin binding);GO:0030175(filopodium);GO:0017166(vinculin binding);GO:0031527(filopodium membrane);GO:0070938(contractile ring);GO:0051015(actin filament binding);GO:0007528(neuromuscular junction development);GO:0014894(response to denervation involved in regulation of muscle adaptation);GO:0016010(dystrophin-associated glycoprotein complex);GO:0030426(growth cone);GO:0030864(cortical actin cytoskeleton);GO:0031594(neuromuscular junction);GO:0042383(sarcolemma);GO:0042383(sarcolemma)","NA","NA","NA","utrophin [Source:HGNC Symbol;Acc:HGNC:12635]",{"v":10.7585195469019,"d":"10.76"},{"v":2.86480191880058,"d":"2.86"},{"v":3.75541480766887,"d":"3.76"},{"v":1.90897227069958,"d":"1.91"},{"v":0.0146273283579035,"d":"0.01"},{"v":0.3136461122229,"d":"0.31"},"up","yes"]
["MSTRG.15350","TAF1","ENST00000276072;ENST00000472567;ENST00000463163;ENST00000474917;ENST00000483985;ENST00000483365;ENST00000423759;ENST00000373790;ENST00000482544;ENST00000467309;ENST00000437147;ENST00000461157","GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0005634(nucleus);GO:0000166(nucleotide binding);GO:0004674(protein serine/threonine kinase activity);GO:0005524(ATP binding);GO:0005654(nucleoplasm);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0016746(transferase activity, transferring acyl groups);GO:0005515(protein binding);GO:0007049(cell cycle);GO:0004402(histone acetyltransferase activity);GO:0016573(histone acetylation);GO:0006352(DNA-templated transcription, initiation);GO:0005669(transcription factor TFIID complex);GO:0000209(protein polyubiquitination);GO:0016032(viral process);GO:0003713(transcription coactivator activity);GO:0006366(transcription from RNA polymerase II promoter);GO:0006368(transcription elongation from RNA polymerase II promoter);GO:0001075(transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly);GO:0006367(transcription initiation from RNA polymerase II promoter);GO:1901796(regulation of signal transduction by p53 class mediator);GO:0000790(nuclear chromatin);GO:0071339(MLL1 complex);GO:0046982(protein heterodimerization activity);GO:0050821(protein stabilization);GO:0046777(protein autophosphorylation);GO:0044212(transcription regulatory region DNA binding);GO:0032436(positive regulation of proteasomal ubiquitin-dependent protein catabolic process);GO:0005730(nucleolus);GO:0018105(peptidyl-serine phosphorylation);GO:0043565(sequence-specific DNA binding);GO:0018107(peptidyl-threonine phosphorylation);GO:0002039(p53 binding);GO:0010629(negative regulation of gene expression);GO:0032092(positive regulation of protein binding);GO:0042787(protein ubiquitination involved in ubiquitin-dependent protein catabolic process);GO:0008134(transcription factor binding);GO:0006974(cellular response to DNA damage stimulus);GO:0060261(positive regulation of transcription initiation from RNA polymerase II promoter);GO:0045943(positive regulation of transcription from RNA polymerase I promoter);GO:0061628(H3K27me3 modified histone binding);GO:0000979(RNA polymerase II core promoter sequence-specific DNA binding);GO:0001129(RNA polymerase II transcription factor activity, TBP-class protein binding, involved in preinitiation complex assembly);GO:0017025(TBP-class protein binding);GO:0061631(ubiquitin conjugating enzyme activity);GO:0070577(lysine-acetylated histone binding);GO:0006468(protein phosphorylation);GO:0008284(positive regulation of cell proliferation);GO:0010767(regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage);GO:0030901(midbrain development);GO:0034644(cellular response to UV);GO:0036369(transcription factor catabolic process);GO:0051123(RNA polymerase II transcriptional preinitiation complex assembly);GO:0060260(regulation of transcription initiation from RNA polymerase II promoter);GO:0071318(cellular response to ATP);GO:1902806(regulation of cell cycle G1/S phase transition);GO:1903026(negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding);GO:1905524(negative regulation of protein autoubiquitination);GO:2000059(negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process);GO:2000825(positive regulation of androgen receptor activity);GO:0005667(transcription factor complex);GO:0005667(transcription factor complex)","03022(Basal transcription factors);03022(Basal transcription factors)","K03125","NA","TATA-box binding protein associated factor 1 [Source:HGNC Symbol;Acc:HGNC:11535]",{"v":4.10333687292818,"d":"4.10"},{"v":1.09079434300184,"d":"1.09"},{"v":3.76178781935731,"d":"3.76"},{"v":1.91141847709242,"d":"1.91"},{"v":0.0146406058232106,"d":"0.01"},{"v":0.3136461122229,"d":"0.31"},"up","yes"]
["MSTRG.5744","SMG1P1;NPIPB5","ENST00000309865;ENST00000424340;ENST00000517539;MSTRG.5744.28;ENST00000431681;ENST00000546168;ENST00000357370;ENST00000442450;ENST00000356156;ENST00000543997;ENST00000544308;ENST00000521555;ENST00000337787;ENST00000308347;ENST00000538590;ENST00000381231;ENST00000517347;ENST00000621622;ENST00000539604;ENST00000538509;ENST00000539929;ENST00000540704;ENST00000415833;ENST00000543407;ENST00000538606;ENST00000415654;ENST00000536620;ENST00000418592;ENST00000446662;ENST00000528249;ENST00000545375","GO:0005654(nucleoplasm);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016021(integral component of membrane)","NA","NA","NA","SMG1P1, nonsense mediated mRNA decay associated PI3K related kinase pseudogene 1 [Source:HGNC Symbol;Acc:HGNC:44186];nuclear pore complex interacting protein family member B5 [Source:HGNC Symbol;Acc:HGNC:37233]",{"v":3.42748661510337,"d":"3.43"},{"v":0.906680942165791,"d":"0.91"},{"v":3.78025659932382,"d":"3.78"},{"v":1.91848416619436,"d":"1.92"},{"v":0.0146408580678135,"d":"0.01"},{"v":0.3136461122229,"d":"0.31"},"up","yes"]
["ENSG00000244041","LINC01011","ENST00000605901;ENST00000445000;ENST00000454015","NA","NA","NA","NA","long intergenic non-protein coding RNA 1011 [Source:HGNC Symbol;Acc:HGNC:33812]",{"v":0.595023430096051,"d":"0.60"},{"v":1.59008654215582,"d":"1.59"},{"v":0.374208204598302,"d":"0.37"},{"v":-1.41808690455153,"d":"-1.42"},{"v":0.0146618771880317,"d":"0.01"},{"v":0.3136461122229,"d":"0.31"},"down","yes"]
["MSTRG.7318","NDUFAF8","ENST00000431388;ENST00000573090;ENST00000573173","GO:0005739(mitochondrion);GO:0005515(protein binding);GO:0032981(mitochondrial respiratory chain complex I assembly);GO:0032981(mitochondrial respiratory chain complex I assembly)","NA","NA","NA","NADH:ubiquinone oxidoreductase complex assembly factor 8 [Source:HGNC Symbol;Acc:HGNC:33551]",{"v":0.935213487645349,"d":"0.94"},{"v":2.51280260174419,"d":"2.51"},{"v":0.372179448953212,"d":"0.37"},{"v":-1.42592970018844,"d":"-1.43"},{"v":0.014665447251962,"d":"0.01"},{"v":0.3136461122229,"d":"0.31"},"down","yes"]
["MSTRG.8590","FOSL2","ENST00000379619;ENST00000264716;ENST00000436647;ENST00000460736","GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0006355(regulation of transcription, DNA-templated);GO:0006366(transcription from RNA polymerase II promoter);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0005515(protein binding);GO:0001228(transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0000977(RNA polymerase II regulatory region sequence-specific DNA binding);GO:0008219(cell death);GO:0003682(chromatin binding);GO:0003334(keratinocyte development);GO:0045893(positive regulation of transcription, DNA-templated);GO:0048146(positive regulation of fibroblast proliferation);GO:0048146(positive regulation of fibroblast proliferation)","04380(Osteoclast differentiation);04380(Osteoclast differentiation)","K09030","NA","FOS like 2, AP-1 transcription factor subunit [Source:HGNC Symbol;Acc:HGNC:3798]",{"v":26.454318399469,"d":"26.45"},{"v":7.06913907852452,"d":"7.07"},{"v":3.74222633132726,"d":"3.74"},{"v":1.90389681598356,"d":"1.90"},{"v":0.0147554042985961,"d":"0.01"},{"v":0.314989908308082,"d":"0.31"},"up","yes"]
["MSTRG.12181","VCAN","ENST00000265077;ENST00000343200;MSTRG.12181.1;ENST00000513016;ENST00000505615;ENST00000513960;ENST00000507162;ENST00000502527;ENST00000515397;ENST00000513984","GO:0005615(extracellular space);GO:0016020(membrane);GO:0030246(carbohydrate binding);GO:0005509(calcium ion binding);GO:0007155(cell adhesion);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0005578(proteinaceous extracellular matrix);GO:0005540(hyaluronic acid binding);GO:0044267(cellular protein metabolic process);GO:0031012(extracellular matrix);GO:0043687(post-translational protein modification);GO:0007275(multicellular organism development);GO:0005788(endoplasmic reticulum lumen);GO:0043202(lysosomal lumen);GO:0030198(extracellular matrix organization);GO:0030203(glycosaminoglycan metabolic process);GO:0005796(Golgi lumen);GO:0005201(extracellular matrix structural constituent);GO:0001501(skeletal system development);GO:0007417(central nervous system development);GO:0030206(chondroitin sulfate biosynthetic process);GO:0030207(chondroitin sulfate catabolic process);GO:0030208(dermatan sulfate biosynthetic process);GO:0001649(osteoblast differentiation);GO:0005539(glycosaminoglycan binding);GO:0008037(cell recognition);GO:0008037(cell recognition)","04514(Cell adhesion molecules (CAMs));04514(Cell adhesion molecules (CAMs))","K06793","NA","versican [Source:HGNC Symbol;Acc:HGNC:2464]",{"v":31.310677166407,"d":"31.31"},{"v":8.38125968995686,"d":"8.38"},{"v":3.73579608849564,"d":"3.74"},{"v":1.90141571036217,"d":"1.90"},{"v":0.014869062845028,"d":"0.01"},{"v":0.316544426268479,"d":"0.32"},"up","yes"]
["MSTRG.1639","SVIL","MSTRG.1639.3;MSTRG.1639.4;ENST00000474106;ENST00000375398;ENST00000355867;ENST00000375400;ENST00000460007;ENST00000490031;ENST00000483758;ENST00000465422;ENST00000491872;ENST00000464984","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005829(cytosol);GO:0003779(actin binding);GO:0051015(actin filament binding);GO:0005886(plasma membrane);GO:0015629(actin cytoskeleton);GO:0005856(cytoskeleton);GO:0042995(cell projection);GO:0005515(protein binding);GO:0030054(cell junction);GO:0005925(focal adhesion);GO:0030496(midbody);GO:0007010(cytoskeleton organization);GO:0002102(podosome);GO:0032154(cleavage furrow);GO:0071437(invadopodium);GO:0032467(positive regulation of cytokinesis);GO:0043034(costamere);GO:0007519(skeletal muscle tissue development);GO:0036449(microtubule minus-end);GO:0036449(microtubule minus-end)","NA","NA","NA","supervillin [Source:HGNC Symbol;Acc:HGNC:11480]",{"v":10.9483518283943,"d":"10.95"},{"v":2.92559227881077,"d":"2.93"},{"v":3.74226849984876,"d":"3.74"},{"v":1.90391307260962,"d":"1.90"},{"v":0.01489140198772,"d":"0.01"},{"v":0.316544426268479,"d":"0.32"},"up","yes"]
["ENSG00000185710","SMG1P4","ENST00000523028;ENST00000540706;ENST00000381448;ENST00000517529;ENST00000380598;ENST00000543702","NA","NA","NA","NA","SMG1P4, nonsense mediated mRNA decay associated PI3K related kinase pseudogene 4 [Source:HGNC Symbol;Acc:HGNC:49861]",{"v":1.37296308426073,"d":"1.37"},{"v":0.354664095389507,"d":"0.35"},{"v":3.87116458110282,"d":"3.87"},{"v":1.95276764456989,"d":"1.95"},{"v":0.0149269115668192,"d":"0.01"},{"v":0.316544426268479,"d":"0.32"},"up","yes"]
["MSTRG.9508","LRRFIP1;RBM44","ENST00000244815;ENST00000289175;ENST00000478958;ENST00000480583;ENST00000474195;ENST00000465870;ENST00000392000;ENST00000420665;ENST00000483443;ENST00000468950;ENST00000473815;ENST00000464608;ENST00000491996;ENST00000308482;ENST00000498053;ENST00000409864","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0005886(plasma membrane);GO:0042803(protein homodimerization activity);GO:0005515(protein binding);GO:0008150(biological_process);GO:0005575(cellular_component);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:0001078(transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0045296(cadherin binding);GO:0045892(negative regulation of transcription, DNA-templated);GO:0005856(cytoskeleton);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0032481(positive regulation of type I interferon production);GO:0003725(double-stranded RNA binding);GO:0051092(positive regulation of NF-kappaB transcription factor activity);GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0045171(intercellular bridge);GO:0045171(intercellular bridge)","NA","NA","NA","LRR binding FLII interacting protein 1 [Source:HGNC Symbol;Acc:HGNC:6702];RNA binding motif protein 44 [Source:HGNC Symbol;Acc:HGNC:24756]",{"v":6.54503400733524,"d":"6.55"},{"v":1.74938801159079,"d":"1.75"},{"v":3.74132780376354,"d":"3.74"},{"v":1.90355037597842,"d":"1.90"},{"v":0.014937255282453,"d":"0.01"},{"v":0.316544426268479,"d":"0.32"},"up","yes"]
["ENSG00000123104","ITPR2","ENST00000381340;ENST00000543958;ENST00000536627;ENST00000540429;ENST00000451599","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0055085(transmembrane transport);GO:0005783(endoplasmic reticulum);GO:0005634(nucleus);GO:0005216(ion channel activity);GO:0006811(ion transport);GO:0005789(endoplasmic reticulum membrane);GO:0006816(calcium ion transport);GO:0070588(calcium ion transmembrane transport);GO:0005262(calcium channel activity);GO:0005509(calcium ion binding);GO:0005220(inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity);GO:0048016(inositol phosphate-mediated signaling);GO:1903779(regulation of cardiac conduction);GO:0007165(signal transduction);GO:0005886(plasma membrane);GO:0030168(platelet activation);GO:0050796(regulation of insulin secretion);GO:0051209(release of sequestered calcium ion into cytosol);GO:0031095(platelet dense tubular network membrane);GO:0033017(sarcoplasmic reticulum membrane);GO:0043235(receptor complex);GO:0001666(response to hypoxia);GO:0015085(calcium ion transmembrane transporter activity);GO:0015278(calcium-release channel activity);GO:0035091(phosphatidylinositol binding);GO:0071320(cellular response to cAMP);GO:0071361(cellular response to ethanol);GO:0005737(cytoplasm);GO:0005938(cell cortex);GO:0016529(sarcoplasmic reticulum);GO:0016529(sarcoplasmic reticulum)","04371(Apelin signaling pathway);04020(Calcium signaling pathway);04070(Phosphatidylinositol signaling system);04022(cGMP - PKG signaling pathway);04114(Oocyte meiosis);04210(Apoptosis);04218(Cellular senescence);04540(Gap junction);04611(Platelet activation);04621(NOD-like receptor signaling pathway);04922(Glucagon signaling pathway);04912(GnRH signaling pathway);04915(Estrogen signaling pathway);04921(Oxytocin signaling pathway);04918(Thyroid hormone synthesis);04924(Renin secretion);04925(Aldosterone synthesis and secretion);04927(Cortisol synthesis and secretion);04270(Vascular smooth muscle contraction);04970(Salivary secretion);04971(Gastric acid secretion);04972(Pancreatic secretion);04724(Glutamatergic synapse);04725(Cholinergic synapse);04728(Dopaminergic synapse);04726(Serotonergic synapse);04720(Long-term potentiation);04730(Long-term depression);04723(Retrograde endocannabinoid signaling);04750(Inflammatory mediator regulation of TRP channels);05205(Proteoglycans in cancer);05010(Alzheimer's disease);05167(Kaposi's sarcoma-associated herpesvirus infection);05167(Kaposi's sarcoma-associated herpesvirus infection)","K04959","NA","inositol 1,4,5-trisphosphate receptor type 2 [Source:HGNC Symbol;Acc:HGNC:6181]",{"v":3.29790517270588,"d":"3.30"},{"v":0.880427663137255,"d":"0.88"},{"v":3.74579912784016,"d":"3.75"},{"v":1.90527353571576,"d":"1.91"},{"v":0.0149845266318478,"d":"0.01"},{"v":0.316663584544383,"d":"0.32"},"up","yes"]
["ENSG00000233013","FAM157B","ENST00000446912;ENST00000540522;ENST00000639350;ENST00000642084","NA","NA","NA","NA","family with sequence similarity 157 member B (non-protein coding) [Source:HGNC Symbol;Acc:HGNC:34080]",{"v":3.62201176603956,"d":"3.62"},{"v":0.942341613603473,"d":"0.94"},{"v":3.84362922506324,"d":"3.84"},{"v":1.94246917353051,"d":"1.94"},{"v":0.0150063374681824,"d":"0.02"},{"v":0.316663584544383,"d":"0.32"},"up","yes"]
["ENSG00000090565","RAB11FIP3","ENST00000262305;ENST00000412256;ENST00000487899;ENST00000495663;ENST00000483002;ENST00000461009;ENST00000434585","GO:0006810(transport);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0016192(vesicle-mediated transport);GO:0043231(intracellular membrane-bounded organelle);GO:0046872(metal ion binding);GO:0005654(nucleoplasm);GO:0005509(calcium ion binding);GO:0051301(cell division);GO:0045171(intercellular bridge);GO:0042803(protein homodimerization activity);GO:0032456(endocytic recycling);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0007049(cell cycle);GO:0005815(microtubule organizing center);GO:0017137(Rab GTPase binding);GO:0005813(centrosome);GO:0030496(midbody);GO:0030306(ADP-ribosylation factor binding);GO:0000910(cytokinesis);GO:0005768(endosome);GO:0005829(cytosol);GO:0032154(cleavage furrow);GO:0055037(recycling endosome);GO:0055038(recycling endosome membrane);GO:0051959(dynein light intermediate chain binding);GO:0061512(protein localization to cilium);GO:0070164(negative regulation of adiponectin secretion);GO:0005622(intracellular);GO:0005622(intracellular)","04144(Endocytosis);04144(Endocytosis)","K12485","NA","RAB11 family interacting protein 3 [Source:HGNC Symbol;Acc:HGNC:17224]",{"v":1.72097220389425,"d":"1.72"},{"v":0.446659305999683,"d":"0.45"},{"v":3.85298633830652,"d":"3.85"},{"v":1.94597707058288,"d":"1.95"},{"v":0.0150246822598773,"d":"0.02"},{"v":0.316663584544383,"d":"0.32"},"up","yes"]
["MSTRG.12516","CCNJL","ENST00000257536;ENST00000393977;ENST00000520748;ENST00000519673;ENST00000377503","GO:0005634(nucleus);GO:0005515(protein binding);GO:0005515(protein binding)","NA","NA","NA","cyclin J like [Source:HGNC Symbol;Acc:HGNC:25876]",{"v":5.67421896663851,"d":"5.67"},{"v":1.50976529476351,"d":"1.51"},{"v":3.75834507941006,"d":"3.76"},{"v":1.91009753655511,"d":"1.91"},{"v":0.0151471772457963,"d":"0.02"},{"v":0.318666973469987,"d":"0.32"},"up","yes"]
["ENSG00000135974","C2orf49","ENST00000258457;ENST00000410049","GO:0003674(molecular_function);GO:0008150(biological_process);GO:0005654(nucleoplasm);GO:0048598(embryonic morphogenesis);GO:0072669(tRNA-splicing ligase complex);GO:0006388(tRNA splicing, via endonucleolytic cleavage and ligation);GO:0006388(tRNA splicing, via endonucleolytic cleavage and ligation)","NA","NA","NA","chromosome 2 open reading frame 49 [Source:HGNC Symbol;Acc:HGNC:28772]",{"v":1.08303763716443,"d":"1.08"},{"v":2.81620706208054,"d":"2.82"},{"v":0.384573155769416,"d":"0.38"},{"v":-1.37867003265149,"d":"-1.38"},{"v":0.0151856751809826,"d":"0.02"},{"v":0.318757347567027,"d":"0.32"},"down","yes"]
["ENSG00000145012","LPP","ENST00000617246;ENST00000640853;ENST00000487347;ENST00000415906;ENST00000430340;ENST00000448637;ENST00000618621;ENST00000457242;ENST00000416784;ENST00000414139;ENST00000484468;ENST00000494233;ENST00000459897","GO:0005829(cytosol);GO:0005925(focal adhesion);GO:0046872(metal ion binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0007155(cell adhesion);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0030054(cell junction);GO:0008150(biological_process);GO:0008150(biological_process)","NA","NA","NA","LIM domain containing preferred translocation partner in lipoma [Source:HGNC Symbol;Acc:HGNC:6679]",{"v":1.7899107092618,"d":"1.79"},{"v":0.478683641511651,"d":"0.48"},{"v":3.73923517337961,"d":"3.74"},{"v":1.90274321010994,"d":"1.90"},{"v":0.0152144878667967,"d":"0.02"},{"v":0.318757347567027,"d":"0.32"},"up","yes"]
["ENSG00000188559","RALGAPA2","ENST00000202677;ENST00000430436;ENST00000424981;ENST00000427175","GO:0005634(nucleus);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0005096(GTPase activator activity);GO:0043547(positive regulation of GTPase activity);GO:0051056(regulation of small GTPase mediated signal transduction);GO:0005737(cytoplasm);GO:0005615(extracellular space);GO:0090630(activation of GTPase activity);GO:0046982(protein heterodimerization activity);GO:0046982(protein heterodimerization activity)","NA","NA","NA","Ral GTPase activating protein catalytic alpha subunit 2 [Source:HGNC Symbol;Acc:HGNC:16207]",{"v":3.87367254636636,"d":"3.87"},{"v":1.0371859773887,"d":"1.04"},{"v":3.73479070370679,"d":"3.73"},{"v":1.90102739718192,"d":"1.90"},{"v":0.0152338179539912,"d":"0.02"},{"v":0.318757347567027,"d":"0.32"},"up","yes"]
["MSTRG.13786","RPS3AP26","ENST00000398259","NA","NA","NA","NA","ribosomal protein S3a pseudogene 26 [Source:HGNC Symbol;Acc:HGNC:36513]",{"v":20.047489,"d":"20.05"},{"v":51.422928,"d":"51.42"},{"v":0.389855066207043,"d":"0.39"},{"v":-1.3589902122625,"d":"-1.36"},{"v":0.0153497242306996,"d":"0.02"},{"v":0.320604941530782,"d":"0.32"},"down","yes"]
["ENSG00000173230","GOLGB1","ENST00000614479;ENST00000393667;ENST00000482512;ENST00000340645;ENST00000472475;ENST00000494517;ENST00000472829;ENST00000489400;ENST00000491690","GO:0003723(RNA binding);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005794(Golgi apparatus);GO:0006355(regulation of transcription, DNA-templated);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0043565(sequence-specific DNA binding);GO:0005515(protein binding);GO:0000139(Golgi membrane);GO:0006888(ER to Golgi vesicle-mediated transport);GO:0005793(endoplasmic reticulum-Golgi intermediate compartment);GO:0005795(Golgi stack);GO:0007030(Golgi organization);GO:1905793(protein localization to pericentriolar material);GO:0005801(cis-Golgi network);GO:0005801(cis-Golgi network)","NA","NA","NA","golgin B1 [Source:HGNC Symbol;Acc:HGNC:4429]",{"v":6.38302568040455,"d":"6.38"},{"v":1.71760719924147,"d":"1.72"},{"v":3.71623132647757,"d":"3.72"},{"v":1.89384030881818,"d":"1.89"},{"v":0.0154055432411971,"d":"0.02"},{"v":0.321120658464447,"d":"0.32"},"up","yes"]
["MSTRG.11344","FNDC3B","ENST00000415807;ENST00000336824;ENST00000421757;ENST00000483344;ENST00000416957;ENST00000476794;ENST00000478016;ENST00000490832;ENST00000423424;ENST00000469491;ENST00000494000;ENST00000443501","GO:0003723(RNA binding);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016021(integral component of membrane)","NA","NA","NA","fibronectin type III domain containing 3B [Source:HGNC Symbol;Acc:HGNC:24670]",{"v":4.5910458270535,"d":"4.59"},{"v":1.23193860542577,"d":"1.23"},{"v":3.72668394904857,"d":"3.73"},{"v":1.89789247281659,"d":"1.90"},{"v":0.0154297190582245,"d":"0.02"},{"v":0.321120658464447,"d":"0.32"},"up","yes"]
["MSTRG.12565","RNF44","ENST00000274811;ENST00000513029;MSTRG.12565.2;MSTRG.12565.3;ENST00000515051;ENST00000506378;ENST00000509404;ENST00000508478;ENST00000504160;ENST00000504434;MSTRG.12565.8","GO:0046872(metal ion binding);GO:0016567(protein ubiquitination);GO:0061630(ubiquitin protein ligase activity);GO:0043161(proteasome-mediated ubiquitin-dependent protein catabolic process);GO:0043161(proteasome-mediated ubiquitin-dependent protein catabolic process)","NA","NA","NA","ring finger protein 44 [Source:HGNC Symbol;Acc:HGNC:19180]",{"v":20.2152891482332,"d":"20.22"},{"v":5.44436598657244,"d":"5.44"},{"v":3.71306580014838,"d":"3.71"},{"v":1.89261088177133,"d":"1.89"},{"v":0.0155187576315245,"d":"0.02"},{"v":0.321500769391694,"d":"0.32"},"up","yes"]
["MSTRG.8976","CNNM3","ENST00000305510;ENST00000377060;ENST00000480035;ENST00000465224;ENST00000494595","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0006811(ion transport);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0005515(protein binding)","NA","NA","NA","cyclin and CBS domain divalent metal cation transport mediator 3 [Source:HGNC Symbol;Acc:HGNC:104]",{"v":4.10593631793478,"d":"4.11"},{"v":1.09244783990036,"d":"1.09"},{"v":3.75847355632949,"d":"3.76"},{"v":1.91014685343331,"d":"1.91"},{"v":0.0155264792111281,"d":"0.02"},{"v":0.321500769391694,"d":"0.32"},"up","yes"]
["MSTRG.4586","SEL1L","ENST00000336735;ENST00000555923;ENST00000554293;ENST00000557372;ENST00000555824;ENST00000554744","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0044322(endoplasmic reticulum quality control compartment);GO:0007219(Notch signaling pathway);GO:0005515(protein binding);GO:0030433(ubiquitin-dependent ERAD pathway);GO:0030970(retrograde protein transport, ER to cytosol);GO:0055085(transmembrane transport);GO:1904380(endoplasmic reticulum mannose trimming);GO:0050821(protein stabilization);GO:0036503(ERAD pathway);GO:0009306(protein secretion);GO:0006641(triglyceride metabolic process);GO:0036513(Derlin-1 retrotranslocation complex);GO:0000836(Hrd1p ubiquitin ligase complex);GO:0000839(Hrd1p ubiquitin ligase ERAD-L complex);GO:0034976(response to endoplasmic reticulum stress);GO:0034976(response to endoplasmic reticulum stress)","04141(Protein processing in endoplasmic reticulum);04141(Protein processing in endoplasmic reticulum)","K14026","NA","SEL1L ERAD E3 ligase adaptor subunit [Source:HGNC Symbol;Acc:HGNC:10717]",{"v":12.6932636921226,"d":"12.69"},{"v":3.41928364358196,"d":"3.42"},{"v":3.71225818482419,"d":"3.71"},{"v":1.89229705233301,"d":"1.89"},{"v":0.0155417043177882,"d":"0.02"},{"v":0.321500769391694,"d":"0.32"},"up","yes"]
["ENSG00000131149","GSE1","ENST00000253458;ENST00000637419;ENST00000469381;ENST00000393243;ENST00000495192;ENST00000562659;ENST00000635906;ENST00000496345;ENST00000411612","GO:0005515(protein binding);GO:0005515(protein binding)","NA","NA","NA","Gse1 coiled-coil protein [Source:HGNC Symbol;Acc:HGNC:28979]",{"v":2.94722742832599,"d":"2.95"},{"v":0.790340186823037,"d":"0.79"},{"v":3.72906183623672,"d":"3.73"},{"v":1.89881272044017,"d":"1.90"},{"v":0.0155587214671602,"d":"0.02"},{"v":0.321500769391694,"d":"0.32"},"up","yes"]
["MSTRG.7555","TSHZ1","ENST00000322038;ENST00000580243;ENST00000584217","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0007275(multicellular organism development);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0003682(chromatin binding);GO:0010468(regulation of gene expression);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0001078(transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0009952(anterior/posterior pattern specification);GO:0042474(middle ear morphogenesis);GO:0060023(soft palate development);GO:0060023(soft palate development)","NA","NA","NA","teashirt zinc finger homeobox 1 [Source:HGNC Symbol;Acc:HGNC:10669]",{"v":1.05112215070644,"d":"1.05"},{"v":0.277083428571429,"d":"0.28"},{"v":3.79352224752579,"d":"3.79"},{"v":1.92353799858985,"d":"1.92"},{"v":0.0158028814631103,"d":"0.02"},{"v":0.325026933723564,"d":"0.33"},"up","yes"]
["ENSG00000134265","NAPG","ENST00000322897;ENST00000580746;ENST00000582472;ENST00000580483;ENST00000583367;ENST00000582978","GO:0006810(transport);GO:0016020(membrane);GO:0006886(intracellular protein transport);GO:0015031(protein transport);GO:0005765(lysosomal membrane);GO:0005739(mitochondrion);GO:0016192(vesicle-mediated transport);GO:0019905(syntaxin binding);GO:0005515(protein binding);GO:0070062(extracellular exosome);GO:0050821(protein stabilization);GO:0031201(SNARE complex);GO:0061025(membrane fusion);GO:0006461(protein complex assembly);GO:0006891(intra-Golgi vesicle-mediated transport);GO:0005483(soluble NSF attachment protein activity);GO:0043209(myelin sheath);GO:0005622(intracellular);GO:0005622(intracellular)","NA","NA","NA","NSF attachment protein gamma [Source:HGNC Symbol;Acc:HGNC:7642]",{"v":2.79359616917293,"d":"2.79"},{"v":0.741203288220551,"d":"0.74"},{"v":3.76900131660192,"d":"3.77"},{"v":1.91418229897009,"d":"1.91"},{"v":0.0158269407577294,"d":"0.02"},{"v":0.325026933723564,"d":"0.33"},"up","yes"]
["MSTRG.7583","ARID3A","ENST00000592216;ENST00000590749;ENST00000263620;ENST00000585733;MSTRG.7583.2;ENST00000457152","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0043231(intracellular membrane-bounded organelle);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0006366(transcription from RNA polymerase II promoter);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0006977(DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest);GO:0000977(RNA polymerase II regulatory region sequence-specific DNA binding);GO:0001228(transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding);GO:0045121(membrane raft);GO:0003682(chromatin binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0042803(protein homodimerization activity);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0045944(positive regulation of transcription from RNA polymerase II promoter)","NA","NA","NA","AT-rich interaction domain 3A [Source:HGNC Symbol;Acc:HGNC:3031]",{"v":5.29531287669903,"d":"5.30"},{"v":1.42649099070735,"d":"1.43"},{"v":3.71212500548164,"d":"3.71"},{"v":1.89224529391157,"d":"1.89"},{"v":0.015832530093953,"d":"0.02"},{"v":0.325026933723564,"d":"0.33"},"up","yes"]
["ENSG00000262919","FAM58A","ENST00000576892;ENST00000621629;ENST00000429336;ENST00000621817;ENST00000440428;ENST00000620088;ENST00000614850","GO:0005515(protein binding);GO:0032147(activation of protein kinase activity);GO:0005634(nucleus);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0016538(cyclin-dependent protein serine/threonine kinase regulator activity);GO:0045737(positive regulation of cyclin-dependent protein serine/threonine kinase activity);GO:1901409(positive regulation of phosphorylation of RNA polymerase II C-terminal domain);GO:0000307(cyclin-dependent protein kinase holoenzyme complex);GO:0030295(protein kinase activator activity);GO:0043410(positive regulation of MAPK cascade);GO:0043410(positive regulation of MAPK cascade)","NA","NA","NA","family with sequence similarity 58 member A [Source:HGNC Symbol;Acc:HGNC:28434]",{"v":3.70080166820809,"d":"3.70"},{"v":9.5225694132948,"d":"9.52"},{"v":0.388634779919931,"d":"0.39"},{"v":-1.36351307771934,"d":"-1.36"},{"v":0.0158431392814348,"d":"0.02"},{"v":0.325026933723564,"d":"0.33"},"down","yes"]
["ENSG00000143126","CELSR2","ENST00000271332;ENST00000498157;ENST00000459940;ENST00000489018","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0004930(G-protein coupled receptor activity);GO:0007186(G-protein coupled receptor signaling pathway);GO:0005509(calcium ion binding);GO:0007155(cell adhesion);GO:0007156(homophilic cell adhesion via plasma membrane adhesion molecules);GO:0005886(plasma membrane);GO:0004871(signal transducer activity);GO:0007165(signal transduction);GO:0004888(transmembrane signaling receptor activity);GO:0007166(cell surface receptor signaling pathway);GO:0007275(multicellular organism development);GO:0048813(dendrite morphogenesis);GO:0060071(Wnt signaling pathway, planar cell polarity pathway);GO:0006355(regulation of transcription, DNA-templated);GO:0016055(Wnt signaling pathway);GO:0022407(regulation of cell-cell adhesion);GO:0021999(neural plate anterior/posterior regionalization);GO:0021999(neural plate anterior/posterior regionalization)","NA","NA","NA","cadherin EGF LAG seven-pass G-type receptor 2 [Source:HGNC Symbol;Acc:HGNC:3231]",{"v":0.396041889221799,"d":"0.40"},{"v":0.102867081868977,"d":"0.10"},{"v":3.85003523018415,"d":"3.85"},{"v":1.94487164741258,"d":"1.94"},{"v":0.0158693077948214,"d":"0.02"},{"v":0.325026933723564,"d":"0.33"},"up","yes"]
["MSTRG.13949",null,"MSTRG.13949.1","NA","NA","NA","NA",null,{"v":4.947439,"d":"4.95"},{"v":1.301932,"d":"1.30"},{"v":3.80007481189494,"d":"3.80"},{"v":1.92602782110554,"d":"1.93"},{"v":0.0159914508326501,"d":"0.02"},{"v":0.326184152724815,"d":"0.33"},"up","yes"]
["MSTRG.1192","PRRC2C","ENST00000367742;ENST00000495585;ENST00000470689;ENST00000426496;ENST00000480806;ENST00000463586;ENST00000498596;ENST00000476522;ENST00000492811;ENST00000338920","GO:0003723(RNA binding);GO:0016020(membrane);GO:0008022(protein C-terminus binding);GO:0002244(hematopoietic progenitor cell differentiation);GO:0002244(hematopoietic progenitor cell differentiation)","NA","NA","NA","proline rich coiled-coil 2C [Source:HGNC Symbol;Acc:HGNC:24903]",{"v":15.0828528593492,"d":"15.08"},{"v":4.08655596192802,"d":"4.09"},{"v":3.69084701148523,"d":"3.69"},{"v":1.88395193797747,"d":"1.88"},{"v":0.0160223149535388,"d":"0.02"},{"v":0.326184152724815,"d":"0.33"},"up","yes"]
["MSTRG.12074","NDUFAF2","ENST00000296597;ENST00000512623;ENST00000511107","GO:0016020(membrane);GO:0005739(mitochondrion);GO:0008137(NADH dehydrogenase (ubiquinone) activity);GO:0009055(electron carrier activity);GO:0022904(respiratory electron transport chain);GO:0045333(cellular respiration);GO:0061179(negative regulation of insulin secretion involved in cellular response to glucose stimulus);GO:0072593(reactive oxygen species metabolic process);GO:0032981(mitochondrial respiratory chain complex I assembly);GO:0005743(mitochondrial inner membrane);GO:0005743(mitochondrial inner membrane)","NA","NA","NA","NADH:ubiquinone oxidoreductase complex assembly factor 2 [Source:HGNC Symbol;Acc:HGNC:28086]",{"v":1.92227372861357,"d":"1.92"},{"v":5.03266581612586,"d":"5.03"},{"v":0.381959342989584,"d":"0.38"},{"v":-1.38850901366546,"d":"-1.39"},{"v":0.01605162691707,"d":"0.02"},{"v":0.326184152724815,"d":"0.33"},"down","yes"]
["ENSG00000183530","PRR14L","ENST00000327423;ENST00000412743;ENST00000492705;ENST00000461722;ENST00000431684;ENST00000330495","NA","NA","NA","NA","proline rich 14 like [Source:HGNC Symbol;Acc:HGNC:28738]",{"v":5.49571521686849,"d":"5.50"},{"v":1.48663531323567,"d":"1.49"},{"v":3.69674739187181,"d":"3.70"},{"v":1.88625646388085,"d":"1.89"},{"v":0.0160777496591063,"d":"0.02"},{"v":0.326184152724815,"d":"0.33"},"up","yes"]
["MSTRG.5712","GDE1","ENST00000353258;ENST00000564172;ENST00000563645;ENST00000569773;ENST00000569899","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0046872(metal ion binding);GO:0016787(hydrolase activity);GO:0006629(lipid metabolic process);GO:0005886(plasma membrane);GO:0030659(cytoplasmic vesicle membrane);GO:0031410(cytoplasmic vesicle);GO:0008081(phosphoric diester hydrolase activity);GO:0008889(glycerophosphodiester phosphodiesterase activity);GO:0046475(glycerophospholipid catabolic process);GO:0004622(lysophospholipase activity);GO:0047395(glycerophosphoinositol glycerophosphodiesterase activity);GO:0006644(phospholipid metabolic process);GO:0070291(N-acylethanolamine metabolic process);GO:0070291(N-acylethanolamine metabolic process)","NA","NA","NA","glycerophosphodiester phosphodiesterase 1 [Source:HGNC Symbol;Acc:HGNC:29644]",{"v":4.93503129166667,"d":"4.94"},{"v":12.5610885262681,"d":"12.56"},{"v":0.392882454521867,"d":"0.39"},{"v":-1.34783035401746,"d":"-1.35"},{"v":0.0160900691972652,"d":"0.02"},{"v":0.326184152724815,"d":"0.33"},"down","yes"]
["MSTRG.10003","IL10RB-AS1","ENST00000411998","NA","NA","NA","NA","IL10RB antisense RNA 1 (head to head) [Source:HGNC Symbol;Acc:HGNC:44303]",{"v":3.552531,"d":"3.55"},{"v":0.940179,"d":"0.94"},{"v":3.77856876190598,"d":"3.78"},{"v":1.91783987701009,"d":"1.92"},{"v":0.0160943356162334,"d":"0.02"},{"v":0.326184152724815,"d":"0.33"},"up","yes"]
["MSTRG.12548","HRH2","MSTRG.12548.3;MSTRG.12548.2;ENST00000624694;ENST00000377291;MSTRG.12548.4;ENST00000231683;ENST00000636584","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0004930(G-protein coupled receptor activity);GO:0007186(G-protein coupled receptor signaling pathway);GO:0005886(plasma membrane);GO:0004871(signal transducer activity);GO:0007165(signal transduction);GO:0001696(gastric acid secretion);GO:0004969(histamine receptor activity);GO:0045907(positive regulation of vasoconstriction);GO:0005887(integral component of plasma membrane);GO:0006955(immune response);GO:0007187(G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger);GO:0001697(histamine-induced gastric acid secretion);GO:0001698(gastrin-induced gastric acid secretion);GO:0003382(epithelial cell morphogenesis);GO:0007613(memory);GO:0008542(visual learning);GO:0048167(regulation of synaptic plasticity);GO:0048565(digestive tract development);GO:0048732(gland development);GO:1901998(toxin transport);GO:1901998(toxin transport)","04020(Calcium signaling pathway);04080(Neuroactive ligand-receptor interaction);04971(Gastric acid secretion);04971(Gastric acid secretion)","K04150","NA","histamine receptor H2 [Source:HGNC Symbol;Acc:HGNC:5183]",{"v":21.2846235502354,"d":"21.28"},{"v":5.77227801801656,"d":"5.77"},{"v":3.6873871084867,"d":"3.69"},{"v":1.88259888108536,"d":"1.88"},{"v":0.0161249471354991,"d":"0.02"},{"v":0.326235210948695,"d":"0.33"},"up","yes"]
["ENSG00000112182","BACH2","ENST00000537989;ENST00000470301;ENST00000257749;ENST00000406998;ENST00000494747;ENST00000472023;ENST00000481150","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0016567(protein ubiquitination);GO:0004842(ubiquitin-protein transferase activity);GO:0031463(Cul3-RING ubiquitin ligase complex);GO:0000980(RNA polymerase II distal enhancer sequence-specific DNA binding);GO:0006366(transcription from RNA polymerase II promoter);GO:0001206(transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:1902593(single-organism nuclear import);GO:1902593(single-organism nuclear import)","NA","NA","NA","BTB domain and CNC homolog 2 [Source:HGNC Symbol;Acc:HGNC:14078]",{"v":4.03343238248518,"d":"4.03"},{"v":1.09018196576742,"d":"1.09"},{"v":3.69977903610421,"d":"3.70"},{"v":1.88743911046161,"d":"1.89"},{"v":0.0161622274418851,"d":"0.02"},{"v":0.326420777882803,"d":"0.33"},"up","yes"]
["ENSG00000275395","FCGBP","ENST00000616721;ENST00000620799;ENST00000641975","NA","NA","NA","NA","Fc fragment of IgG binding protein [Source:HGNC Symbol;Acc:HGNC:13572]",{"v":3.03703874261245,"d":"3.04"},{"v":0.821878257156084,"d":"0.82"},{"v":3.69524162023875,"d":"3.70"},{"v":1.88566870075128,"d":"1.89"},{"v":0.0162217066814654,"d":"0.02"},{"v":0.32705326335392,"d":"0.33"},"up","yes"]
["MSTRG.5856","FBRS","ENST00000356166;ENST00000287468;ENST00000484152;ENST00000494101;ENST00000543786;MSTRG.5856.2;ENST00000570170;ENST00000498588;ENST00000468966","NA","NA","NA","NA","fibrosin [Source:HGNC Symbol;Acc:HGNC:20442]",{"v":9.17632000595733,"d":"9.18"},{"v":2.48926122388473,"d":"2.49"},{"v":3.68636281235153,"d":"3.69"},{"v":1.88219806820725,"d":"1.88"},{"v":0.0163389126102591,"d":"0.02"},{"v":0.328845393661939,"d":"0.33"},"up","yes"]
["MSTRG.14957","RPL35","ENST00000348462;ENST00000487431;ENST00000493018;ENST00000495728;ENST00000373570;ENST00000629845","GO:0005622(intracellular);GO:0003735(structural constituent of ribosome);GO:0006412(translation);GO:0005840(ribosome);GO:0003723(RNA binding);GO:0016020(membrane);GO:0030529(intracellular ribonucleoprotein complex);GO:0005829(cytosol);GO:0006413(translational initiation);GO:0006364(rRNA processing);GO:0005730(nucleolus);GO:0000184(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay);GO:0019083(viral transcription);GO:0006614(SRP-dependent cotranslational protein targeting to membrane);GO:0022625(cytosolic large ribosomal subunit);GO:0003729(mRNA binding);GO:0000463(maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA));GO:0000463(maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA))","03010(Ribosome);03010(Ribosome)","K02918","NA","ribosomal protein L35 [Source:HGNC Symbol;Acc:HGNC:10344]",{"v":109.742374801303,"d":"109.74"},{"v":277.23301002215,"d":"277.23"},{"v":0.39584887381389,"d":"0.40"},{"v":-1.33697834794923,"d":"-1.34"},{"v":0.0164279064824194,"d":"0.02"},{"v":0.329171377907277,"d":"0.33"},"down","yes"]
["ENSG00000162104","ADCY9","ENST00000294016;ENST00000571889;ENST00000572288;ENST00000574721;ENST00000575550;ENST00000571467;ENST00000576936","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0035556(intracellular signal transduction);GO:0016829(lyase activity);GO:0005886(plasma membrane);GO:0005887(integral component of plasma membrane);GO:0016849(phosphorus-oxygen lyase activity);GO:0009190(cyclic nucleotide biosynthetic process);GO:0004016(adenylate cyclase activity);GO:0006171(cAMP biosynthetic process);GO:0007193(adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway);GO:0007165(signal transduction);GO:0004383(guanylate cyclase activity);GO:0003091(renal water homeostasis);GO:0006182(cGMP biosynthetic process);GO:0007189(adenylate cyclase-activating G-protein coupled receptor signaling pathway);GO:0007190(activation of adenylate cyclase activity);GO:0034199(activation of protein kinase A activity);GO:0071377(cellular response to glucagon stimulus);GO:0008074(guanylate cyclase complex, soluble);GO:0071880(adenylate cyclase-activating adrenergic receptor signaling pathway);GO:0030424(axon);GO:0030425(dendrite);GO:0005622(intracellular);GO:0005622(intracellular)","00230(Purine metabolism);04015(Rap1 signaling pathway);04371(Apelin signaling pathway);04020(Calcium signaling pathway);04072(Phospholipase D signaling pathway);04024(cAMP signaling pathway);04022(cGMP - PKG signaling pathway);04114(Oocyte meiosis);04540(Gap junction);04611(Platelet activation);04062(Chemokine signaling pathway);04911(Insulin secretion);04923(Regulation of lipolysis in adipocyte);04912(GnRH signaling pathway);04913(Ovarian Steroidogenesis);04915(Estrogen signaling pathway);04914(Progesterone-mediated oocyte maturation);04921(Oxytocin signaling pathway);04926(Relaxin signaling pathway);04918(Thyroid hormone synthesis);04916(Melanogenesis);04925(Aldosterone synthesis and secretion);04927(Cortisol synthesis and secretion);04261(Adrenergic signaling in cardiomyocytes);04270(Vascular smooth muscle contraction);04970(Salivary secretion);04971(Gastric acid secretion);04972(Pancreatic secretion);04976(Bile secretion);04962(Vasopressin-regulated water reabsorption);04961(Endocrine and other factor-regulated calcium reabsorption);04724(Glutamatergic synapse);04727(GABAergic synapse);04725(Cholinergic synapse);04723(Retrograde endocannabinoid signaling);04750(Inflammatory mediator regulation of TRP channels);04211(Longevity regulating pathway - mammal);04213(Longevity regulating pathway - multiple species);04713(Circadian entrainment);05200(Pathways in cancer);05032(Morphine addiction);05414(Dilated cardiomyopathy (DCM));05110(Vibrio cholerae infection);05166(HTLV-I infection);01522(Endocrine resistance);01522(Endocrine resistance)","K08049","EC:4.6.1.1","adenylate cyclase 9 [Source:HGNC Symbol;Acc:HGNC:240]",{"v":1.54664246563043,"d":"1.55"},{"v":0.416034730546437,"d":"0.42"},{"v":3.7175801731721,"d":"3.72"},{"v":1.89436385571161,"d":"1.89"},{"v":0.0164453571275715,"d":"0.02"},{"v":0.329171377907277,"d":"0.33"},"up","yes"]
["MSTRG.8878","TMEM150A","ENST00000451147;ENST00000433956;ENST00000409668;ENST00000417791;ENST00000431593;ENST00000334462;ENST00000444380;ENST00000463363;ENST00000306353","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0005887(integral component of plasma membrane);GO:0005764(lysosome);GO:0090002(establishment of protein localization to plasma membrane);GO:0046854(phosphatidylinositol phosphorylation);GO:0009056(catabolic process);GO:0009056(catabolic process)","NA","NA","NA","transmembrane protein 150A [Source:HGNC Symbol;Acc:HGNC:24677]",{"v":0.523931189722043,"d":"0.52"},{"v":1.36670658403361,"d":"1.37"},{"v":0.383353088250842,"d":"0.38"},{"v":-1.38325429280236,"d":"-1.38"},{"v":0.0164580930264495,"d":"0.02"},{"v":0.329171377907277,"d":"0.33"},"down","yes"]
["ENSG00000188486","H2AFX","ENST00000530167;ENST00000375167","GO:0005634(nucleus);GO:0016607(nuclear speck);GO:0005654(nucleoplasm);GO:0003677(DNA binding);GO:0046982(protein heterodimerization activity);GO:0006334(nucleosome assembly);GO:0000786(nucleosome);GO:0005694(chromosome);GO:0005515(protein binding);GO:0006281(DNA repair);GO:0006310(DNA recombination);GO:0006974(cellular response to DNA damage stimulus);GO:0007049(cell cycle);GO:0051321(meiotic cell cycle);GO:0005813(centrosome);GO:0000790(nuclear chromatin);GO:0070062(extracellular exosome);GO:0016032(viral process);GO:0019899(enzyme binding);GO:0042393(histone binding);GO:0000781(chromosome, telomeric region);GO:0000077(DNA damage checkpoint);GO:0006342(chromatin silencing);GO:0045739(positive regulation of DNA repair);GO:0006302(double-strand break repair);GO:0006303(double-strand break repair via nonhomologous end joining);GO:0010212(response to ionizing radiation);GO:0007283(spermatogenesis);GO:0021987(cerebral cortex development);GO:0071480(cellular response to gamma radiation);GO:0090398(cellular senescence);GO:0035861(site of double-strand break);GO:0035861(site of double-strand break)","04217(Necroptosis);05322(Systemic lupus erythematosus);05034(Alcoholism);05034(Alcoholism)","K11251","NA","H2A histone family member X [Source:HGNC Symbol;Acc:HGNC:4739]",{"v":1.62172780421314,"d":"1.62"},{"v":4.20484094114002,"d":"4.20"},{"v":0.385681129658487,"d":"0.39"},{"v":-1.37451953438636,"d":"-1.37"},{"v":0.0164684896722749,"d":"0.02"},{"v":0.329171377907277,"d":"0.33"},"down","yes"]
["MSTRG.6707","SLFN12L","MSTRG.6707.1","NA","NA","NA","NA",null,{"v":5.628275,"d":"5.63"},{"v":1.486958,"d":"1.49"},{"v":3.78509345926381,"d":"3.79"},{"v":1.92032892281386,"d":"1.92"},{"v":0.016501994084857,"d":"0.02"},{"v":0.329274325270523,"d":"0.33"},"up","yes"]
["MSTRG.13788","ZNF394","ENST00000337673;ENST00000481881;ENST00000426306;ENST00000485576;ENST00000464401;ENST00000394177;ENST00000462024","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0005622(intracellular);GO:0005515(protein binding);GO:0005515(protein binding)","NA","NA","NA","zinc finger protein 394 [Source:HGNC Symbol;Acc:HGNC:18832]",{"v":2.57479651554921,"d":"2.57"},{"v":6.53671692182596,"d":"6.54"},{"v":0.39389750945953,"d":"0.39"},{"v":-1.34410779979817,"d":"-1.34"},{"v":0.0166662206349246,"d":"0.02"},{"v":0.331084134499863,"d":"0.33"},"down","yes"]
["MSTRG.6991","UBE2Z","ENST00000360943;ENST00000504684;ENST00000513342;ENST00000514948;ENST00000506271;ENST00000511373","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0016740(transferase activity);GO:0016567(protein ubiquitination);GO:0005515(protein binding);GO:0006915(apoptotic process);GO:0031625(ubiquitin protein ligase binding);GO:0061630(ubiquitin protein ligase activity);GO:0043065(positive regulation of apoptotic process);GO:0061631(ubiquitin conjugating enzyme activity);GO:0042787(protein ubiquitination involved in ubiquitin-dependent protein catabolic process);GO:0042787(protein ubiquitination involved in ubiquitin-dependent protein catabolic process)","04120(Ubiquitin mediated proteolysis);04120(Ubiquitin mediated proteolysis)","K10585","EC:2.3.2.23","ubiquitin conjugating enzyme E2 Z [Source:HGNC Symbol;Acc:HGNC:25847]",{"v":3.64879139544585,"d":"3.65"},{"v":9.22101691569616,"d":"9.22"},{"v":0.395703795883382,"d":"0.40"},{"v":-1.33750719011285,"d":"-1.34"},{"v":0.0166793765950484,"d":"0.02"},{"v":0.331084134499863,"d":"0.33"},"down","yes"]
["MSTRG.12715","U91328.2","ENST00000606723","NA","NA","NA","NA",null,{"v":0.195553,"d":"0.20"},{"v":0.534681,"d":"0.53"},{"v":0.365737701545407,"d":"0.37"},{"v":-1.45111874239718,"d":"-1.45"},{"v":0.0166820982635231,"d":"0.02"},{"v":0.331084134499863,"d":"0.33"},"down","yes"]
["MSTRG.2088","RASSF7","ENST00000397582;ENST00000454668;ENST00000524468;ENST00000528736;ENST00000397583;ENST00000531112;ENST00000414138;ENST00000431809","GO:0005737(cytoplasm);GO:0007165(signal transduction);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0006915(apoptotic process);GO:0005815(microtubule organizing center);GO:0070507(regulation of microtubule cytoskeleton organization);GO:0070507(regulation of microtubule cytoskeleton organization)","NA","NA","NA","Ras association domain family member 7 [Source:HGNC Symbol;Acc:HGNC:1166]",{"v":1.98899575922953,"d":"1.99"},{"v":5.08238617455859,"d":"5.08"},{"v":0.391350773222634,"d":"0.39"},{"v":-1.35346579956148,"d":"-1.35"},{"v":0.016729154806076,"d":"0.02"},{"v":0.331084134499863,"d":"0.33"},"down","yes"]
["MSTRG.11579","RPL9","MSTRG.11579.3;ENST00000511075;ENST00000449470;MSTRG.11579.1;ENST00000514842;ENST00000295955;ENST00000504470;MSTRG.11579.4;ENST00000511643;ENST00000503040;ENST00000506581;ENST00000503277;ENST00000437992;ENST00000508595","GO:0005634(nucleus);GO:0016020(membrane);GO:0006412(translation);GO:0030529(intracellular ribonucleoprotein complex);GO:0005622(intracellular);GO:0003735(structural constituent of ribosome);GO:0005840(ribosome);GO:0005515(protein binding);GO:0019843(rRNA binding);GO:0005925(focal adhesion);GO:0005829(cytosol);GO:0031012(extracellular matrix);GO:0002181(cytoplasmic translation);GO:0006413(translational initiation);GO:0003723(RNA binding);GO:0006364(rRNA processing);GO:0000184(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay);GO:0019083(viral transcription);GO:0006614(SRP-dependent cotranslational protein targeting to membrane);GO:0022625(cytosolic large ribosomal subunit);GO:0022625(cytosolic large ribosomal subunit)","03010(Ribosome);03010(Ribosome)","K02940","NA","ribosomal protein L9 [Source:HGNC Symbol;Acc:HGNC:10369]",{"v":25.9034654461491,"d":"25.90"},{"v":65.2765612457809,"d":"65.28"},{"v":0.396826440483235,"d":"0.40"},{"v":-1.33341993941661,"d":"-1.33"},{"v":0.0167352438604512,"d":"0.02"},{"v":0.331084134499863,"d":"0.33"},"down","yes"]
["MSTRG.122","RERE","ENST00000377464;ENST00000488215;ENST00000460659;ENST00000476556;ENST00000464367;ENST00000492766;MSTRG.122.3;ENST00000505225;ENST00000468247;ENST00000400908;MSTRG.122.2;ENST00000480342;ENST00000464972;ENST00000465125;ENST00000337907","GO:0005634(nucleus);GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0043565(sequence-specific DNA binding);GO:0005515(protein binding);GO:0007275(multicellular organism development);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0001105(RNA polymerase II transcription coactivator activity);GO:0001106(RNA polymerase II transcription corepressor activity);GO:0003682(chromatin binding);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0006338(chromatin remodeling);GO:0021549(cerebellum development);GO:0021691(cerebellar Purkinje cell layer maturation);GO:0021930(cerebellar granule cell precursor proliferation);GO:0021942(radial glia guided migration of Purkinje cell);GO:0048755(branching morphogenesis of a nerve);GO:0048813(dendrite morphogenesis);GO:0000118(histone deacetylase complex);GO:0006607(NLS-bearing protein import into nucleus);GO:0008267(poly-glutamine tract binding);GO:0008267(poly-glutamine tract binding)","NA","NA","NA","arginine-glutamic acid dipeptide repeats [Source:HGNC Symbol;Acc:HGNC:9965]",{"v":8.58973292693509,"d":"8.59"},{"v":2.34592574678931,"d":"2.35"},{"v":3.66155362704519,"d":"3.66"},{"v":1.87245592567925,"d":"1.87"},{"v":0.01688663220634,"d":"0.02"},{"v":0.333351749194382,"d":"0.33"},"up","yes"]
["ENSG00000184634","MED12","ENST00000374080;ENST00000333646;ENST00000460771;ENST00000471663;ENST00000462984;ENST00000429213;ENST00000489199;ENST00000444034;ENST00000374102","GO:0005634(nucleus);GO:0016020(membrane);GO:0008013(beta-catenin binding);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0001104(RNA polymerase II transcription cofactor activity);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0016592(mediator complex);GO:0005515(protein binding);GO:0030374(ligand-dependent nuclear receptor transcription coactivator activity);GO:0045893(positive regulation of transcription, DNA-templated);GO:0006367(transcription initiation from RNA polymerase II promoter);GO:0005654(nucleoplasm);GO:0004872(receptor activity);GO:0030178(negative regulation of Wnt signaling pathway);GO:0008022(protein C-terminus binding);GO:0003713(transcription coactivator activity);GO:0019904(protein domain specific binding);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0003712(transcription cofactor activity);GO:0030518(intracellular steroid hormone receptor signaling pathway);GO:0030521(androgen receptor signaling pathway);GO:0042809(vitamin D receptor binding);GO:0046966(thyroid hormone receptor binding);GO:0001105(RNA polymerase II transcription coactivator activity);GO:0000980(RNA polymerase II distal enhancer sequence-specific DNA binding);GO:0001190(transcriptional activator activity, RNA polymerase II transcription factor binding);GO:0003682(chromatin binding);GO:0008134(transcription factor binding);GO:0061630(ubiquitin protein ligase activity);GO:0001756(somitogenesis);GO:0001843(neural tube closure);GO:0007492(endoderm development);GO:0007507(heart development);GO:0014003(oligodendrocyte development);GO:0014044(Schwann cell development);GO:0016567(protein ubiquitination);GO:0019827(stem cell population maintenance);GO:0021510(spinal cord development);GO:0021915(neural tube development);GO:0036342(post-anal tail morphogenesis);GO:0048568(embryonic organ development);GO:0048702(embryonic neurocranium morphogenesis);GO:0060070(canonical Wnt signaling pathway);GO:0060071(Wnt signaling pathway, planar cell polarity pathway);GO:0090245(axis elongation involved in somitogenesis);GO:1990403(embryonic brain development);GO:0000151(ubiquitin ligase complex);GO:0000151(ubiquitin ligase complex)","04919(Thyroid hormone signaling pathway);04919(Thyroid hormone signaling pathway)","K15162","NA","mediator complex subunit 12 [Source:HGNC Symbol;Acc:HGNC:11957]",{"v":8.79837548498316,"d":"8.80"},{"v":2.40055933185185,"d":"2.40"},{"v":3.6651356074569,"d":"3.67"},{"v":1.8738665780552,"d":"1.87"},{"v":0.0169072746297676,"d":"0.02"},{"v":0.333351749194382,"d":"0.33"},"up","yes"]
["MSTRG.8659","ZFP36L2","ENST00000282388","GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0003677(DNA binding);GO:0030529(intracellular ribonucleoprotein complex);GO:0007275(multicellular organism development);GO:0006355(regulation of transcription, DNA-templated);GO:0005515(protein binding);GO:0061158(3'-UTR-mediated mRNA destabilization);GO:1900153(positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay);GO:0005829(cytosol);GO:0071356(cellular response to tumor necrosis factor);GO:0070371(ERK1 and ERK2 cascade);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0045599(negative regulation of fat cell differentiation);GO:0071560(cellular response to transforming growth factor beta stimulus);GO:0008283(cell proliferation);GO:0030097(hemopoiesis);GO:0044344(cellular response to fibroblast growth factor stimulus);GO:0017091(AU-rich element binding);GO:0009611(response to wounding);GO:0071364(cellular response to epidermal growth factor stimulus);GO:0006402(mRNA catabolic process);GO:2000737(negative regulation of stem cell differentiation);GO:0060216(definitive hemopoiesis);GO:0033077(T cell differentiation in thymus);GO:0097011(cellular response to granulocyte macrophage colony-stimulating factor stimulus);GO:0043488(regulation of mRNA stability);GO:0035925(mRNA 3'-UTR AU-rich region binding);GO:0000165(MAPK cascade);GO:0000288(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay);GO:0035019(somatic stem cell population maintenance);GO:0045577(regulation of B cell differentiation);GO:0048103(somatic stem cell division);GO:0071385(cellular response to glucocorticoid stimulus);GO:1901991(negative regulation of mitotic cell cycle phase transition);GO:1904628(cellular response to phorbol 13-acetate 12-myristate)","04218(Cellular senescence)","K18753","NA","ZFP36 ring finger protein like 2 [Source:HGNC Symbol;Acc:HGNC:1108]",{"v":86.982864,"d":"86.98"},{"v":23.853144,"d":"23.85"},{"v":3.64659954260118,"d":"3.65"},{"v":1.86655177641523,"d":"1.87"},{"v":0.0170353963286543,"d":"0.02"},{"v":0.334782040658094,"d":"0.33"},"up","yes"]
["ENSG00000135837","CEP350","ENST00000367607;ENST00000417046;ENST00000490047;ENST00000429851;ENST00000496440;ENST00000490141;ENST00000357434;ENST00000491495;ENST00000418229","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005813(centrosome);GO:0005856(cytoskeleton);GO:0008017(microtubule binding);GO:0005815(microtubule organizing center);GO:0005819(spindle);GO:0034453(microtubule anchoring);GO:0005515(protein binding);GO:0005515(protein binding)","NA","NA","NA","centrosomal protein 350 [Source:HGNC Symbol;Acc:HGNC:24238]",{"v":6.37003842990001,"d":"6.37"},{"v":1.74346788462345,"d":"1.74"},{"v":3.65365974680732,"d":"3.65"},{"v":1.86934228682525,"d":"1.87"},{"v":0.0170374740402078,"d":"0.02"},{"v":0.334782040658094,"d":"0.33"},"up","yes"]
["ENSG00000154102","C16orf74","ENST00000284245;ENST00000602675;ENST00000602583;ENST00000602914;ENST00000602766;ENST00000602758","GO:0005515(protein binding);GO:0005515(protein binding)","NA","NA","NA","chromosome 16 open reading frame 74 [Source:HGNC Symbol;Acc:HGNC:23362]",{"v":0.605598925722146,"d":"0.61"},{"v":1.59522135992664,"d":"1.60"},{"v":0.379633159970975,"d":"0.38"},{"v":-1.39732208135794,"d":"-1.40"},{"v":0.0171145344290924,"d":"0.02"},{"v":0.335728189738259,"d":"0.34"},"down","yes"]
["MSTRG.8048","AC139769.2","ENST00000599944","NA","NA","NA","NA",null,{"v":0.990547,"d":"0.99"},{"v":2.557491,"d":"2.56"},{"v":0.387312017911304,"d":"0.39"},{"v":-1.36843182741719,"d":"-1.37"},{"v":0.017204140527527,"d":"0.02"},{"v":0.336499826020816,"d":"0.34"},"down","yes"]
["MSTRG.14746","SIT1","ENST00000474403;ENST00000259608;ENST00000618781;ENST00000486859","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0007165(signal transduction);GO:0005886(plasma membrane);GO:0002376(immune system process);GO:0002250(adaptive immune response);GO:0043029(T cell homeostasis);GO:0050863(regulation of T cell activation);GO:0005515(protein binding);GO:0070062(extracellular exosome);GO:0005887(integral component of plasma membrane);GO:0019900(kinase binding);GO:0042169(SH2 domain binding);GO:0042169(SH2 domain binding)","NA","NA","NA","signaling threshold regulating transmembrane adaptor 1 [Source:HGNC Symbol;Acc:HGNC:17710]",{"v":12.3525899329314,"d":"12.35"},{"v":31.0130921567445,"d":"31.01"},{"v":0.398302428874221,"d":"0.40"},{"v":-1.32806381750987,"d":"-1.33"},{"v":0.0172118226691092,"d":"0.02"},{"v":0.336499826020816,"d":"0.34"},"down","yes"]
["MSTRG.7889","RFX1","ENST00000254325;ENST00000589760;ENST00000586913;ENST00000589239;ENST00000588520;ENST00000588885","GO:0005634(nucleus);GO:0043231(intracellular membrane-bounded organelle);GO:0005654(nucleoplasm);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:0006955(immune response);GO:0003705(transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding);GO:0003705(transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding)","NA","NA","NA","regulatory factor X1 [Source:HGNC Symbol;Acc:HGNC:9982]",{"v":4.32067762836231,"d":"4.32"},{"v":1.17427376065874,"d":"1.17"},{"v":3.67944662745296,"d":"3.68"},{"v":1.87948880762458,"d":"1.88"},{"v":0.0172768042723075,"d":"0.02"},{"v":0.336923172034074,"d":"0.34"},"up","yes"]
["ENSG00000173517","PEAK1","ENST00000560626;ENST00000567337;ENST00000312493;ENST00000558305;ENST00000569692","GO:0005737(cytoplasm);GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0004713(protein tyrosine kinase activity);GO:0018108(peptidyl-tyrosine phosphorylation);GO:0005856(cytoskeleton);GO:0004715(non-membrane spanning protein tyrosine kinase activity);GO:0030054(cell junction);GO:0005925(focal adhesion);GO:0005515(protein binding);GO:0016477(cell migration);GO:0046777(protein autophosphorylation);GO:0015629(actin cytoskeleton);GO:0034446(substrate adhesion-dependent cell spreading);GO:0034446(substrate adhesion-dependent cell spreading)","NA","NA","NA","pseudopodium enriched atypical kinase 1 [Source:HGNC Symbol;Acc:HGNC:29431]",{"v":0.807242307889514,"d":"0.81"},{"v":0.2196213392739,"d":"0.22"},{"v":3.67560962226337,"d":"3.68"},{"v":1.87798354956179,"d":"1.88"},{"v":0.0173069710094919,"d":"0.02"},{"v":0.336923172034074,"d":"0.34"},"up","yes"]
["ENSG00000253729","PRKDC","ENST00000314191;ENST00000338368;ENST00000536710;ENST00000546304;ENST00000535375;ENST00000521331;ENST00000540819;ENST00000432581;ENST00000541488;ENST00000536483","GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0005634(nucleus);GO:0003723(RNA binding);GO:0016020(membrane);GO:0000166(nucleotide binding);GO:0004674(protein serine/threonine kinase activity);GO:0005524(ATP binding);GO:0005654(nucleoplasm);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0006303(double-strand break repair via nonhomologous end joining);GO:0006281(DNA repair);GO:0006310(DNA recombination);GO:0006974(cellular response to DNA damage stimulus);GO:0048511(rhythmic process);GO:0005730(nucleolus);GO:0016567(protein ubiquitination);GO:0005829(cytosol);GO:0000784(nuclear chromosome, telomeric region);GO:0031012(extracellular matrix);GO:0005667(transcription factor complex);GO:0001933(negative regulation of protein phosphorylation);GO:0043234(protein complex);GO:0019904(protein domain specific binding);GO:0006464(cellular protein modification process);GO:0004672(protein kinase activity);GO:0032481(positive regulation of type I interferon production);GO:0042752(regulation of circadian rhythm);GO:0018105(peptidyl-serine phosphorylation);GO:0032869(cellular response to insulin stimulus);GO:0008134(transcription factor binding);GO:0032993(protein-DNA complex);GO:0043066(negative regulation of apoptotic process);GO:0008283(cell proliferation);GO:0006468(protein phosphorylation);GO:0003690(double-stranded DNA binding);GO:0048660(regulation of smooth muscle cell proliferation);GO:0070419(nonhomologous end joining complex);GO:0006302(double-strand break repair);GO:0005958(DNA-dependent protein kinase-DNA ligase 4 complex);GO:0004677(DNA-dependent protein kinase activity);GO:0019899(enzyme binding);GO:0000723(telomere maintenance);GO:0001756(somitogenesis);GO:0002326(B cell lineage commitment);GO:0002328(pro-B cell differentiation);GO:0002360(T cell lineage commitment);GO:0002377(immunoglobulin production);GO:0002638(negative regulation of immunoglobulin production);GO:0002684(positive regulation of immune system process);GO:0007420(brain development);GO:0007507(heart development);GO:0008630(intrinsic apoptotic signaling pathway in response to DNA damage);GO:0010212(response to ionizing radiation);GO:0010332(response to gamma radiation);GO:0014823(response to activity);GO:0016233(telomere capping);GO:0030098(lymphocyte differentiation);GO:0031648(protein destabilization);GO:0033077(T cell differentiation in thymus);GO:0033151(V(D)J recombination);GO:0033152(immunoglobulin V(D)J recombination);GO:0033153(T cell receptor V(D)J recombination);GO:0035234(ectopic germ cell programmed cell death);GO:0043065(positive regulation of apoptotic process);GO:0048146(positive regulation of fibroblast proliferation);GO:0048536(spleen development);GO:0048538(thymus development);GO:0048639(positive regulation of developmental growth);GO:0072431(signal transduction involved in mitotic G1 DNA damage checkpoint);GO:0097681(double-strand break repair via alternative nonhomologous end joining);GO:2000773(negative regulation of cellular senescence);GO:2001229(negative regulation of response to gamma radiation);GO:2001229(negative regulation of response to gamma radiation)","03450(Non-homologous end-joining);04110(Cell cycle);04110(Cell cycle)","K06642","EC:2.7.11.1","protein kinase, DNA-activated, catalytic polypeptide [Source:HGNC Symbol;Acc:HGNC:9413]",{"v":7.43396109262502,"d":"7.43"},{"v":2.04223089336447,"d":"2.04"},{"v":3.64011783230737,"d":"3.64"},{"v":1.86398515188937,"d":"1.86"},{"v":0.0173205143980317,"d":"0.02"},{"v":0.336923172034074,"d":"0.34"},"up","yes"]
["ENSG00000163235","TGFA","ENST00000295400;ENST00000418333;ENST00000394241;ENST00000460808;ENST00000445399;ENST00000444975","GO:0005615(extracellular space);GO:0048471(perinuclear region of cytoplasm);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0008083(growth factor activity);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0005887(integral component of plasma membrane);GO:0000139(Golgi membrane);GO:0005789(endoplasmic reticulum membrane);GO:0009986(cell surface);GO:0006888(ER to Golgi vesicle-mediated transport);GO:0031410(cytoplasmic vesicle);GO:0008283(cell proliferation);GO:0048208(COPII vesicle coating);GO:0012507(ER to Golgi transport vesicle membrane);GO:0033116(endoplasmic reticulum-Golgi intermediate compartment membrane);GO:0051781(positive regulation of cell division);GO:0005154(epidermal growth factor receptor binding);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0016323(basolateral plasma membrane);GO:0045741(positive regulation of epidermal growth factor-activated receptor activity);GO:0045840(positive regulation of mitotic nuclear division);GO:0000187(activation of MAPK activity);GO:0050679(positive regulation of epithelial cell proliferation);GO:0001525(angiogenesis);GO:0007173(epidermal growth factor receptor signaling pathway);GO:0008284(positive regulation of cell proliferation);GO:0042060(wound healing);GO:0042493(response to drug);GO:0043066(negative regulation of apoptotic process);GO:0048523(negative regulation of cellular process);GO:0050731(positive regulation of peptidyl-tyrosine phosphorylation);GO:0060749(mammary gland alveolus development);GO:0072574(hepatocyte proliferation);GO:0005634(nucleus);GO:0005634(nucleus)","04014(Ras signaling pathway);04010(MAPK signaling pathway);04012(ErbB signaling pathway);04151(PI3K-Akt signaling pathway);05200(Pathways in cancer);05212(Pancreatic cancer);05225(Hepatocellular carcinoma);05214(Glioma);05211(Renal cell carcinoma);05215(Prostate cancer);05223(Non-small cell lung cancer);01521(EGFR tyrosine kinase inhibitor resistance);01521(EGFR tyrosine kinase inhibitor resistance)","K08774","NA","transforming growth factor alpha [Source:HGNC Symbol;Acc:HGNC:11765]",{"v":0.848525832963933,"d":"0.85"},{"v":2.15892922587145,"d":"2.16"},{"v":0.393030870486931,"d":"0.39"},{"v":-1.3472854619218,"d":"-1.35"},{"v":0.0176934503380353,"d":"0.02"},{"v":0.342810582661028,"d":"0.34"},"down","yes"]
["MSTRG.14241","TNFRSF10C","ENST00000356864;ENST00000518135;ENST00000517558;ENST00000397703;ENST00000520607","GO:0016020(membrane);GO:0005886(plasma membrane);GO:0006915(apoptotic process);GO:0031225(anchored component of membrane);GO:0006955(immune response);GO:0006954(inflammatory response);GO:0097190(apoptotic signaling pathway);GO:0005887(integral component of plasma membrane);GO:0045569(TRAIL binding);GO:0033209(tumor necrosis factor-mediated signaling pathway);GO:0007165(signal transduction);GO:0005031(tumor necrosis factor-activated receptor activity);GO:0007275(multicellular organism development);GO:0032496(response to lipopolysaccharide);GO:0042127(regulation of cell proliferation);GO:0042981(regulation of apoptotic process);GO:0043154(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process);GO:0004888(transmembrane signaling receptor activity);GO:0004888(transmembrane signaling receptor activity)","04060(Cytokine-cytokine receptor interaction);04210(Apoptosis);04217(Necroptosis);04650(Natural killer cell mediated cytotoxicity);05162(Measles);05164(Influenza A);05164(Influenza A)","K04722","NA","TNF receptor superfamily member 10c [Source:HGNC Symbol;Acc:HGNC:11906]",{"v":152.879315259429,"d":"152.88"},{"v":42.2147074339048,"d":"42.21"},{"v":3.62147044365499,"d":"3.62"},{"v":1.85657560090765,"d":"1.86"},{"v":0.0177206648511667,"d":"0.02"},{"v":0.342810582661028,"d":"0.34"},"up","yes"]
["ENSG00000232300","FAM215B","ENST00000458392","NA","NA","NA","NA","family with sequence similarity 215 member B (non-protein coding) [Source:HGNC Symbol;Acc:HGNC:43639]",{"v":1.479859,"d":"1.48"},{"v":0.386072,"d":"0.39"},{"v":3.83311662073396,"d":"3.83"},{"v":1.93851789211054,"d":"1.94"},{"v":0.0177253850949483,"d":"0.02"},{"v":0.342810582661028,"d":"0.34"},"up","yes"]
["ENSG00000189298","ZKSCAN3","ENST00000252211;ENST00000377255","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0005622(intracellular);GO:0005515(protein binding);GO:0006914(autophagy);GO:0045893(positive regulation of transcription, DNA-templated);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:0001078(transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0003682(chromatin binding);GO:0043565(sequence-specific DNA binding);GO:0045892(negative regulation of transcription, DNA-templated);GO:0007040(lysosome organization);GO:0010507(negative regulation of autophagy);GO:2000773(negative regulation of cellular senescence);GO:2000773(negative regulation of cellular senescence)","NA","NA","NA","zinc finger with KRAB and SCAN domains 3 [Source:HGNC Symbol;Acc:HGNC:13853]",{"v":0.295157343453119,"d":"0.30"},{"v":0.763281079306072,"d":"0.76"},{"v":0.386695480151896,"d":"0.39"},{"v":-1.37073019315233,"d":"-1.37"},{"v":0.0177635611314442,"d":"0.02"},{"v":0.342810582661028,"d":"0.34"},"down","yes"]
["MSTRG.280","CD52","MSTRG.280.1;ENST00000492808;ENST00000470468;ENST00000374213","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005886(plasma membrane);GO:0031225(anchored component of membrane);GO:0005576(extracellular region);GO:0006501(C-terminal protein lipidation);GO:0005887(integral component of plasma membrane);GO:0007204(positive regulation of cytosolic calcium ion concentration);GO:0045730(respiratory burst);GO:0045730(respiratory burst)","NA","NA","NA","CD52 molecule [Source:HGNC Symbol;Acc:HGNC:1804]",{"v":98.9800005482456,"d":"98.98"},{"v":246.633765140351,"d":"246.63"},{"v":0.40132380289422,"d":"0.40"},{"v":-1.31716136862479,"d":"-1.32"},{"v":0.0177707716147368,"d":"0.02"},{"v":0.342810582661028,"d":"0.34"},"down","yes"]
["MSTRG.541","CMPK1","ENST00000371873;ENST00000371871;ENST00000471289;ENST00000371870;ENST00000450808","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0005730(nucleolus);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0006139(nucleobase-containing compound metabolic process);GO:0006207('de novo' pyrimidine nucleobase biosynthetic process);GO:0006221(pyrimidine nucleotide biosynthetic process);GO:0019205(nucleobase-containing compound kinase activity);GO:0004550(nucleoside diphosphate kinase activity);GO:0046939(nucleotide phosphorylation);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0004127(cytidylate kinase activity);GO:0009041(uridylate kinase activity);GO:0006165(nucleoside diphosphate phosphorylation);GO:0015949(nucleobase-containing small molecule interconversion);GO:0009142(nucleoside triphosphate biosynthetic process);GO:0050145(nucleoside phosphate kinase activity);GO:0046940(nucleoside monophosphate phosphorylation);GO:0004849(uridine kinase activity);GO:0006222(UMP biosynthetic process);GO:0009220(pyrimidine ribonucleotide biosynthetic process);GO:0009220(pyrimidine ribonucleotide biosynthetic process)","00240(Pyrimidine metabolism);00983(Drug metabolism - other enzymes);00983(Drug metabolism - other enzymes)","K13800","EC:2.7.4.14","cytidine/uridine monophosphate kinase 1 [Source:HGNC Symbol;Acc:HGNC:18170]",{"v":9.46450317013528,"d":"9.46"},{"v":23.5942329229969,"d":"23.59"},{"v":0.401136294662514,"d":"0.40"},{"v":-1.31783558831934,"d":"-1.32"},{"v":0.0178412666359859,"d":"0.02"},{"v":0.343599717153739,"d":"0.34"},"down","yes"]
["MSTRG.7063","SUPT4H1;RNF43","ENST00000581166;ENST00000577396;ENST00000581540;ENST00000580947;ENST00000225504;ENST00000579289;MSTRG.7063.1;ENST00000582293;ENST00000581204","GO:0005634(nucleus);GO:0008270(zinc ion binding);GO:0006355(regulation of transcription, DNA-templated);GO:0032786(positive regulation of DNA-templated transcription, elongation);GO:0046872(metal ion binding);GO:0006351(transcription, DNA-templated);GO:0005515(protein binding);GO:0006368(transcription elongation from RNA polymerase II promoter);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0005654(nucleoplasm);GO:0003727(single-stranded RNA binding);GO:0046982(protein heterodimerization activity);GO:0006366(transcription from RNA polymerase II promoter);GO:0032785(negative regulation of DNA-templated transcription, elongation);GO:0050434(positive regulation of viral transcription);GO:0032044(DSIF complex);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0006338(chromatin remodeling);GO:0000993(RNA polymerase II core binding);GO:0006397(mRNA processing);GO:0034243(regulation of transcription elongation from RNA polymerase II promoter);GO:0034244(negative regulation of transcription elongation from RNA polymerase II promoter);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016740(transferase activity);GO:0016567(protein ubiquitination);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005886(plasma membrane);GO:0016055(Wnt signaling pathway);GO:0005887(integral component of plasma membrane);GO:0030178(negative regulation of Wnt signaling pathway);GO:0042787(protein ubiquitination involved in ubiquitin-dependent protein catabolic process);GO:0004842(ubiquitin-protein transferase activity);GO:0005635(nuclear envelope);GO:0005109(frizzled binding);GO:0061630(ubiquitin protein ligase activity);GO:0072089(stem cell proliferation);GO:0038018(Wnt receptor catabolic process);GO:0034244(negative regulation of transcription elongation from RNA polymerase II promoter)","NA","NA","NA","SPT4 homolog, DSIF elongation factor subunit [Source:HGNC Symbol;Acc:HGNC:11467];ring finger protein 43 [Source:HGNC Symbol;Acc:HGNC:18505]",{"v":3.14667268740133,"d":"3.15"},{"v":7.84032198855384,"d":"7.84"},{"v":0.401344828949013,"d":"0.40"},{"v":-1.31708578529244,"d":"-1.32"},{"v":0.0179406761877608,"d":"0.02"},{"v":0.344530577728047,"d":"0.34"},"down","yes"]
["MSTRG.8101","PPP1R14A","ENST00000301242;ENST00000591585;ENST00000587515","GO:0005737(cytoplasm);GO:0042325(regulation of phosphorylation);GO:0043086(negative regulation of catalytic activity);GO:0004864(protein phosphatase inhibitor activity);GO:0005829(cytosol);GO:0035690(cellular response to drug);GO:0035690(cellular response to drug)","04270(Vascular smooth muscle contraction);04270(Vascular smooth muscle contraction)","K12328","NA","protein phosphatase 1 regulatory inhibitor subunit 14A [Source:HGNC Symbol;Acc:HGNC:14871]",{"v":1.99400583677548,"d":"1.99"},{"v":5.05394640506329,"d":"5.05"},{"v":0.394544317837994,"d":"0.39"},{"v":-1.34174073245841,"d":"-1.34"},{"v":0.0179489364957779,"d":"0.02"},{"v":0.344530577728047,"d":"0.34"},"down","yes"]
["MSTRG.12110","MRPS27","ENST00000261413;ENST00000523654;ENST00000519874;ENST00000522562;ENST00000519143;ENST00000520285;ENST00000513900;ENST00000508863;ENST00000515404;ENST00000522585;ENST00000522095;ENST00000522042;ENST00000457646;ENST00000515226","GO:0030529(intracellular ribonucleoprotein complex);GO:0005840(ribosome);GO:0005739(mitochondrion);GO:0005515(protein binding);GO:0005743(mitochondrial inner membrane);GO:0070125(mitochondrial translational elongation);GO:0070126(mitochondrial translational termination);GO:0070126(mitochondrial translational termination)","NA","NA","NA","mitochondrial ribosomal protein S27 [Source:HGNC Symbol;Acc:HGNC:14512]",{"v":1.75324932944248,"d":"1.75"},{"v":4.37980646106589,"d":"4.38"},{"v":0.400302923206292,"d":"0.40"},{"v":-1.32083594386383,"d":"-1.32"},{"v":0.0180515615675996,"d":"0.02"},{"v":0.345928687268208,"d":"0.35"},"down","yes"]
["ENSG00000172460","PRSS30P","ENST00000476276;ENST00000475030;ENST00000506153;ENST00000390681","NA","NA","NA","NA","protease, serine, 30 pseudogene [Source:HGNC Symbol;Acc:HGNC:28753]",{"v":0.447386825059102,"d":"0.45"},{"v":1.15397617257683,"d":"1.15"},{"v":0.387691562175055,"d":"0.39"},{"v":-1.36701875866511,"d":"-1.37"},{"v":0.0180922581360649,"d":"0.02"},{"v":0.346137386711897,"d":"0.35"},"down","yes"]
["MSTRG.6407","CYB5D1;AC104581.5","ENST00000574196;ENST00000571846;ENST00000573940;ENST00000624171;ENST00000332439;ENST00000574357","GO:0046872(metal ion binding);GO:0046872(metal ion binding)","NA","NA","NA","cytochrome b5 domain containing 1 [Source:HGNC Symbol;Acc:HGNC:26516]",{"v":0.136236664355231,"d":"0.14"},{"v":0.361123742822384,"d":"0.36"},{"v":0.3772575663136,"d":"0.38"},{"v":-1.4063782590164,"d":"-1.41"},{"v":0.0181269710850054,"d":"0.02"},{"v":0.346231110543038,"d":"0.35"},"down","yes"]
["MSTRG.7092","TACO1","ENST00000258975;ENST00000581120","GO:0005634(nucleus);GO:0005739(mitochondrion);GO:0005515(protein binding);GO:0006417(regulation of translation);GO:0006417(regulation of translation)","NA","NA","NA","translational activator of cytochrome c oxidase I [Source:HGNC Symbol;Acc:HGNC:24316]",{"v":1.62530333174946,"d":"1.63"},{"v":4.09497323801296,"d":"4.09"},{"v":0.396902064380308,"d":"0.40"},{"v":-1.33314502873634,"d":"-1.33"},{"v":0.0181693520994434,"d":"0.02"},{"v":0.346470748654904,"d":"0.35"},"down","yes"]
["MSTRG.714","TMED5","ENST00000370290;ENST00000370282;ENST00000479918;ENST00000370280;ENST00000483033","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0015031(protein transport);GO:0005794(Golgi apparatus);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005515(protein binding);GO:0090161(Golgi ribbon formation);GO:0005793(endoplasmic reticulum-Golgi intermediate compartment);GO:0033116(endoplasmic reticulum-Golgi intermediate compartment membrane);GO:0070971(endoplasmic reticulum exit site);GO:0005801(cis-Golgi network);GO:0005801(cis-Golgi network)","NA","NA","NA","transmembrane p24 trafficking protein 5 [Source:HGNC Symbol;Acc:HGNC:24251]",{"v":2.74538559726202,"d":"2.75"},{"v":6.82018577162263,"d":"6.82"},{"v":0.402538242973527,"d":"0.40"},{"v":-1.31280224252388,"d":"-1.31"},{"v":0.018255956646453,"d":"0.02"},{"v":0.347521303476716,"d":"0.35"},"down","yes"]
["MSTRG.3950","PROSER1","ENST00000625998;ENST00000492646;ENST00000602899;ENST00000484434;ENST00000352251;ENST00000496138;ENST00000602512;ENST00000436678;ENST00000602534;ENST00000418503","NA","NA","NA","NA","proline and serine rich 1 [Source:HGNC Symbol;Acc:HGNC:20291]",{"v":4.8500769114149,"d":"4.85"},{"v":1.34004318072454,"d":"1.34"},{"v":3.61934375039507,"d":"3.62"},{"v":1.85572813546369,"d":"1.86"},{"v":0.0182842948785218,"d":"0.02"},{"v":0.347521303476716,"d":"0.35"},"up","yes"]
["ENSG00000173372","C1QA","ENST00000374642;ENST00000402322","GO:0005515(protein binding);GO:0005576(extracellular region);GO:0005581(collagen trimer);GO:0006508(proteolysis);GO:0002376(immune system process);GO:0045087(innate immune response);GO:0006958(complement activation, classical pathway);GO:0010039(response to iron ion);GO:0005615(extracellular space);GO:0004252(serine-type endopeptidase activity);GO:0006956(complement activation);GO:0030449(regulation of complement activation);GO:0070062(extracellular exosome);GO:0007267(cell-cell signaling);GO:0005602(complement component C1 complex);GO:0005602(complement component C1 complex)","04610(Complement and coagulation cascades);05322(Systemic lupus erythematosus);05020(Prion diseases);05133(Pertussis);05150(Staphylococcus aureus infection);05142(Chagas disease (American trypanosomiasis));05142(Chagas disease (American trypanosomiasis))","K03986","NA","complement C1q A chain [Source:HGNC Symbol;Acc:HGNC:1241]",{"v":1.1191075259434,"d":"1.12"},{"v":2.86145875157233,"d":"2.86"},{"v":0.391096857617978,"d":"0.39"},{"v":-1.35440215052495,"d":"-1.35"},{"v":0.0184004177967494,"d":"0.02"},{"v":0.349156947505965,"d":"0.35"},"down","yes"]
["ENSG00000151576","QTRT2","ENST00000485050;ENST00000281273;ENST00000460163;ENST00000466870;ENST00000483272;ENST00000466050;ENST00000472599;ENST00000488665;ENST00000462966;ENST00000467703;ENST00000495782;ENST00000462869","GO:0006400(tRNA modification);GO:0016763(transferase activity, transferring pentosyl groups);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0046872(metal ion binding);GO:0008033(tRNA processing);GO:0005739(mitochondrion);GO:0042803(protein homodimerization activity);GO:0005741(mitochondrial outer membrane);GO:0043234(protein complex);GO:0046982(protein heterodimerization activity);GO:0008479(queuine tRNA-ribosyltransferase activity);GO:0101030(tRNA-guanine transglycosylation);GO:0101030(tRNA-guanine transglycosylation)","NA","NA","NA","queuine tRNA-ribosyltransferase accessory subunit 2 [Source:HGNC Symbol;Acc:HGNC:25771]",{"v":1.78697184405264,"d":"1.79"},{"v":0.483818448721132,"d":"0.48"},{"v":3.69347603171419,"d":"3.69"},{"v":1.88497921551795,"d":"1.88"},{"v":0.0184902227242701,"d":"0.02"},{"v":0.3502036253808,"d":"0.35"},"up","yes"]
["ENSG00000154358","OBSCN","ENST00000570156;ENST00000483539;ENST00000636476;ENST00000422127;ENST00000366706;ENST00000494839;ENST00000366704;ENST00000284548;ENST00000474237;ENST00000602685;ENST00000602832","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0005829(cytosol);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0005886(plasma membrane);GO:0005089(Rho guanyl-nucleotide exchange factor activity);GO:0035023(regulation of Rho protein signal transduction);GO:0043547(positive regulation of GTPase activity);GO:0005515(protein binding);GO:0016604(nuclear body);GO:0007275(multicellular organism development);GO:0030154(cell differentiation);GO:0005516(calmodulin binding);GO:0051056(regulation of small GTPase mediated signal transduction);GO:0042383(sarcolemma);GO:0031430(M band);GO:0030018(Z disc);GO:0005085(guanyl-nucleotide exchange factor activity);GO:0043065(positive regulation of apoptotic process);GO:0008307(structural constituent of muscle);GO:0031432(titin binding);GO:0045214(sarcomere organization);GO:0030506(ankyrin binding);GO:0030016(myofibril);GO:0036309(protein localization to M-band);GO:0030017(sarcomere);GO:0030017(sarcomere)","NA","NA","NA","obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF [Source:HGNC Symbol;Acc:HGNC:15719]",{"v":0.679729388665221,"d":"0.68"},{"v":0.187530177020749,"d":"0.19"},{"v":3.62464004174653,"d":"3.62"},{"v":1.85783773008692,"d":"1.86"},{"v":0.0185158896050815,"d":"0.02"},{"v":0.3502036253808,"d":"0.35"},"up","yes"]
["ENSG00000109458","GAB1","ENST00000262994;ENST00000510615;ENST00000507070;ENST00000511109;ENST00000515388;ENST00000514639;ENST00000507334;ENST00000262995;ENST00000512843;ENST00000511836","GO:0009967(positive regulation of signal transduction);GO:0005515(protein binding);GO:0036092(phosphatidylinositol-3-phosphate biosynthetic process);GO:0046854(phosphatidylinositol phosphorylation);GO:0005829(cytosol);GO:0046934(phosphatidylinositol-4,5-bisphosphate 3-kinase activity);GO:0007411(axon guidance);GO:0014066(regulation of phosphatidylinositol 3-kinase signaling);GO:0038111(interleukin-7-mediated signaling pathway);GO:0048015(phosphatidylinositol-mediated signaling);GO:0016303(1-phosphatidylinositol-3-kinase activity);GO:0008283(cell proliferation);GO:0005070(SH3/SH2 adaptor activity);GO:0038128(ERBB2 signaling pathway);GO:0007173(epidermal growth factor receptor signaling pathway);GO:0008286(insulin receptor signaling pathway);GO:0035728(response to hepatocyte growth factor);GO:0035728(response to hepatocyte growth factor)","04014(Ras signaling pathway);04012(ErbB signaling pathway);04072(Phospholipase D signaling pathway);04722(Neurotrophin signaling pathway);05205(Proteoglycans in cancer);05225(Hepatocellular carcinoma);05226(Gastric cancer);05211(Renal cell carcinoma);05100(Bacterial invasion of epithelial cells);01521(EGFR tyrosine kinase inhibitor resistance);01521(EGFR tyrosine kinase inhibitor resistance)","K09593","NA","GRB2 associated binding protein 1 [Source:HGNC Symbol;Acc:HGNC:4066]",{"v":1.35751950914122,"d":"1.36"},{"v":0.372297168989031,"d":"0.37"},{"v":3.64633315055161,"d":"3.65"},{"v":1.86644638054633,"d":"1.87"},{"v":0.0187332909382456,"d":"0.02"},{"v":0.353739362058286,"d":"0.35"},"up","yes"]
["MSTRG.5585","SLX4","ENST00000294008;ENST00000466154;ENST00000486524","GO:0005634(nucleus);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0000790(nuclear chromatin);GO:0030054(cell junction);GO:0006281(DNA repair);GO:0043085(positive regulation of catalytic activity);GO:0005515(protein binding);GO:0006310(DNA recombination);GO:0006974(cellular response to DNA damage stimulus);GO:0006260(DNA replication);GO:0000712(resolution of meiotic recombination intermediates);GO:0036297(interstrand cross-link repair);GO:0000724(double-strand break repair via homologous recombination);GO:0000781(chromosome, telomeric region);GO:0008047(enzyme activator activity);GO:0048476(Holliday junction resolvase complex);GO:0008821(crossover junction endodeoxyribonuclease activity);GO:0090656(t-circle formation);GO:1904357(negative regulation of telomere maintenance via telomere lengthening);GO:0006289(nucleotide-excision repair);GO:1904431(positive regulation of t-circle formation);GO:0000784(nuclear chromosome, telomeric region);GO:0004520(endodeoxyribonuclease activity);GO:0017108(5'-flap endonuclease activity);GO:0061820(telomeric D-loop disassembly);GO:0070522(ERCC4-ERCC1 complex);GO:0048257(3'-flap endonuclease activity);GO:0000706(meiotic DNA double-strand break processing);GO:0010792(DNA double-strand break processing involved in repair via single-strand annealing);GO:0072429(response to intra-S DNA damage checkpoint signaling);GO:0033557(Slx1-Slx4 complex);GO:0033557(Slx1-Slx4 complex)","03460(Fanconi anemia pathway);03460(Fanconi anemia pathway)","K10484","NA","SLX4 structure-specific endonuclease subunit [Source:HGNC Symbol;Acc:HGNC:23845]",{"v":1.20075887021301,"d":"1.20"},{"v":0.327988983121872,"d":"0.33"},{"v":3.66097317898888,"d":"3.66"},{"v":1.87222720421294,"d":"1.87"},{"v":0.0187645959144122,"d":"0.02"},{"v":0.353755279795567,"d":"0.35"},"up","yes"]
["MSTRG.10083","ITGB2-AS1","ENST00000609694;ENST00000441379;ENST00000609592;MSTRG.10083.7;ENST00000429132;ENST00000608043","NA","NA","NA","NA","ITGB2 antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:44304]",{"v":1.46428446809354,"d":"1.46"},{"v":0.39313843797067,"d":"0.39"},{"v":3.72460265053702,"d":"3.72"},{"v":1.89708652364816,"d":"1.90"},{"v":0.0188773190156171,"d":"0.02"},{"v":0.35530357492441,"d":"0.36"},"up","yes"]
["ENSG00000167566","NCKAP5L","ENST00000335999;ENST00000433948;ENST00000491441;ENST00000477361","GO:0005737(cytoplasm);GO:0005856(cytoskeleton);GO:0005874(microtubule);GO:0005813(centrosome);GO:0005815(microtubule organizing center);GO:0005515(protein binding);GO:0001578(microtubule bundle formation);GO:0035371(microtubule plus-end);GO:0007019(microtubule depolymerization);GO:0007019(microtubule depolymerization)","NA","NA","NA","NCK associated protein 5 like [Source:HGNC Symbol;Acc:HGNC:29321]",{"v":1.81534692138443,"d":"1.82"},{"v":0.500571684672435,"d":"0.50"},{"v":3.62654735969007,"d":"3.63"},{"v":1.85859668942687,"d":"1.86"},{"v":0.0189710180848861,"d":"0.02"},{"v":0.356489373818419,"d":"0.36"},"up","yes"]
["ENSG00000175294","CATSPER1","ENST00000312106;ENST00000529244","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0055085(transmembrane transport);GO:0005216(ion channel activity);GO:0005227(calcium activated cation channel activity);GO:0006811(ion transport);GO:0030317(flagellated sperm motility);GO:0036128(CatSper complex);GO:0031514(motile cilium);GO:0005244(voltage-gated ion channel activity);GO:0034765(regulation of ion transmembrane transport);GO:0005886(plasma membrane);GO:0042995(cell projection);GO:0005515(protein binding);GO:0006816(calcium ion transport);GO:0007275(multicellular organism development);GO:0030154(cell differentiation);GO:0005262(calcium channel activity);GO:0070588(calcium ion transmembrane transport);GO:0007283(spermatogenesis);GO:0005929(cilium);GO:0035036(sperm-egg recognition);GO:0008331(high voltage-gated calcium channel activity);GO:0086010(membrane depolarization during action potential);GO:0032570(response to progesterone);GO:0005245(voltage-gated calcium channel activity);GO:0007342(fusion of sperm to egg plasma membrane);GO:0051924(regulation of calcium ion transport);GO:0060296(regulation of cilium beat frequency involved in ciliary motility);GO:0060296(regulation of cilium beat frequency involved in ciliary motility)","NA","NA","NA","cation channel sperm associated 1 [Source:HGNC Symbol;Acc:HGNC:17116]",{"v":0.520446737997767,"d":"0.52"},{"v":1.3298069240789,"d":"1.33"},{"v":0.391370151992747,"d":"0.39"},{"v":-1.35339436246392,"d":"-1.35"},{"v":0.0190748318855292,"d":"0.02"},{"v":0.357861102886349,"d":"0.36"},"down","yes"]
["MSTRG.14992","GOLGA2","ENST00000421699;ENST00000611957;ENST00000609374;ENST00000639983;ENST00000462089;ENST00000468488;ENST00000490628;ENST00000461031;ENST00000486411;ENST00000490257;ENST00000496221;ENST00000450617;ENST00000610329;ENST00000458730;ENST00000470630","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005794(Golgi apparatus);GO:0005634(nucleus);GO:0051301(cell division);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0007049(cell cycle);GO:0005874(microtubule);GO:0006486(protein glycosylation);GO:0005801(cis-Golgi network);GO:0008017(microtubule binding);GO:0000922(spindle pole);GO:0032580(Golgi cisterna membrane);GO:0045296(cadherin binding);GO:0019901(protein kinase binding);GO:0010507(negative regulation of autophagy);GO:0007098(centrosome cycle);GO:0006888(ER to Golgi vesicle-mediated transport);GO:0090307(mitotic spindle assembly);GO:0019905(syntaxin binding);GO:0000139(Golgi membrane);GO:0051289(protein homotetramerization);GO:0048208(COPII vesicle coating);GO:0033116(endoplasmic reticulum-Golgi intermediate compartment membrane);GO:0090161(Golgi ribbon formation);GO:0032091(negative regulation of protein binding);GO:0051225(spindle assembly);GO:0072686(mitotic spindle);GO:0007020(microtubule nucleation);GO:0030134(ER to Golgi transport vesicle);GO:0090166(Golgi disassembly);GO:1904668(positive regulation of ubiquitin protein ligase activity);GO:0061676(importin-alpha family protein binding);GO:0008356(asymmetric cell division);GO:0060050(positive regulation of protein glycosylation);GO:0090306(spindle assembly involved in meiosis);GO:0000137(Golgi cis cisterna);GO:0000137(Golgi cis cisterna)","NA","NA","NA","golgin A2 [Source:HGNC Symbol;Acc:HGNC:4425]",{"v":4.45690662016952,"d":"4.46"},{"v":1.23419581381985,"d":"1.23"},{"v":3.61118273961353,"d":"3.61"},{"v":1.85247142800286,"d":"1.85"},{"v":0.0191492850225471,"d":"0.02"},{"v":0.358155183949428,"d":"0.36"},"up","yes"]
["ENSG00000132436","FIGNL1","ENST00000356889;ENST00000436590;ENST00000419119;ENST00000440350;ENST00000435566;ENST00000448788;ENST00000395556;ENST00000615084","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0016787(hydrolase activity);GO:0005515(protein binding);GO:0000287(magnesium ion binding);GO:0046034(ATP metabolic process);GO:0070062(extracellular exosome);GO:0016887(ATPase activity);GO:0010569(regulation of double-strand break repair via homologous recombination);GO:0043066(negative regulation of apoptotic process);GO:0051726(regulation of cell cycle);GO:0000228(nuclear chromosome);GO:0071479(cellular response to ionizing radiation);GO:0001649(osteoblast differentiation);GO:0033687(osteoblast proliferation);GO:2001243(negative regulation of intrinsic apoptotic signaling pathway);GO:2001243(negative regulation of intrinsic apoptotic signaling pathway)","NA","NA","NA","fidgetin like 1 [Source:HGNC Symbol;Acc:HGNC:13286]",{"v":0.570521938816051,"d":"0.57"},{"v":0.144504556813667,"d":"0.14"},{"v":3.94812420726439,"d":"3.95"},{"v":1.98116737742999,"d":"1.98"},{"v":0.0191521888601218,"d":"0.02"},{"v":0.358155183949428,"d":"0.36"},"up","yes"]
["ENSG00000139132","FGD4","ENST00000531134;ENST00000427716;ENST00000494275;ENST00000472289;ENST00000546442;ENST00000534526;ENST00000493087;ENST00000494977;ENST00000525053","GO:0046872(metal ion binding);GO:0005089(Rho guanyl-nucleotide exchange factor activity);GO:0035023(regulation of Rho protein signal transduction);GO:0043547(positive regulation of GTPase activity);GO:0005737(cytoplasm);GO:0005794(Golgi apparatus);GO:0003779(actin binding);GO:0005856(cytoskeleton);GO:0042995(cell projection);GO:0005085(guanyl-nucleotide exchange factor activity);GO:0005829(cytosol);GO:0030027(lamellipodium);GO:0030175(filopodium);GO:0051056(regulation of small GTPase mediated signal transduction);GO:0007010(cytoskeleton organization);GO:0008360(regulation of cell shape);GO:0001726(ruffle);GO:0030036(actin cytoskeleton organization);GO:0043087(regulation of GTPase activity);GO:0043065(positive regulation of apoptotic process);GO:0046847(filopodium assembly);GO:0031267(small GTPase binding);GO:0030032(lamellipodium assembly);GO:0030035(microspike assembly);GO:0030035(microspike assembly)","NA","NA","NA","FYVE, RhoGEF and PH domain containing 4 [Source:HGNC Symbol;Acc:HGNC:19125]",{"v":1.50159649835356,"d":"1.50"},{"v":0.414087120707498,"d":"0.41"},{"v":3.62628158004039,"d":"3.63"},{"v":1.85849095441342,"d":"1.86"},{"v":0.0192422112147516,"d":"0.02"},{"v":0.358915199483324,"d":"0.36"},"up","yes"]
["MSTRG.9832","NFATC2","ENST00000371564;ENST00000396009;ENST00000496054;ENST00000609943;ENST00000610033","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0006355(regulation of transcription, DNA-templated);GO:0006366(transcription from RNA polymerase II promoter);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0005515(protein binding);GO:0006974(cellular response to DNA damage stimulus);GO:0038095(Fc-epsilon receptor signaling pathway);GO:0030890(positive regulation of B cell proliferation);GO:0050853(B cell receptor signaling pathway);GO:0016477(cell migration);GO:0045893(positive regulation of transcription, DNA-templated);GO:0042493(response to drug);GO:0045589(regulation of regulatory T cell differentiation);GO:0000976(transcription regulatory region sequence-specific DNA binding);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:0000981(RNA polymerase II transcription factor activity, sequence-specific DNA binding);GO:0001077(transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0001078(transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0003682(chromatin binding);GO:0008134(transcription factor binding);GO:0043565(sequence-specific DNA binding);GO:0044212(transcription regulatory region DNA binding);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0001816(cytokine production);GO:0010628(positive regulation of gene expression);GO:0014904(myotube cell development);GO:0033173(calcineurin-NFAT signaling cascade);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:1901741(positive regulation of myoblast fusion);GO:0000790(nuclear chromatin);GO:0005667(transcription factor complex);GO:0030529(intracellular ribonucleoprotein complex);GO:0044798(nuclear transcription factor complex);GO:0044798(nuclear transcription factor complex)","04310(Wnt signaling pathway);04370(VEGF signaling pathway);04022(cGMP - PKG signaling pathway);04218(Cellular senescence);04650(Natural killer cell mediated cytotoxicity);04660(T cell receptor signaling pathway);04658(Th1 and Th2 cell differentiation);04659(Th17 cell differentiation);04662(B cell receptor signaling pathway);04921(Oxytocin signaling pathway);04360(Axon guidance);04380(Osteoclast differentiation);05166(HTLV-I infection);05161(Hepatitis B);05167(Kaposi's sarcoma-associated herpesvirus infection);05167(Kaposi's sarcoma-associated herpesvirus infection)","K17332","NA","nuclear factor of activated T-cells 2 [Source:HGNC Symbol;Acc:HGNC:7776]",{"v":9.05826402630944,"d":"9.06"},{"v":2.53301942589911,"d":"2.53"},{"v":3.57607365095282,"d":"3.58"},{"v":1.83837644982385,"d":"1.84"},{"v":0.0192546430102567,"d":"0.02"},{"v":0.358915199483324,"d":"0.36"},"up","yes"]
["MSTRG.3404","CBX5","ENST00000209875;ENST00000439541;ENST00000552562;ENST00000618078;ENST00000550411","GO:0005634(nucleus);GO:0005694(chromosome);GO:0005515(protein binding);GO:0000775(chromosome, centromeric region);GO:0005654(nucleoplasm);GO:0000784(nuclear chromosome, telomeric region);GO:0016032(viral process);GO:0005635(nuclear envelope);GO:0045892(negative regulation of transcription, DNA-templated);GO:0035064(methylated histone binding);GO:0005730(nucleolus);GO:0030674(protein binding, bridging);GO:0007596(blood coagulation);GO:0017053(transcriptional repressor complex);GO:0016605(PML body);GO:0005721(pericentric heterochromatin);GO:0000118(histone deacetylase complex);GO:0070491(repressing transcription factor binding);GO:0031618(nuclear pericentric heterochromatin);GO:0003682(chromatin binding);GO:0042803(protein homodimerization activity);GO:0042826(histone deacetylase binding);GO:0000776(kinetochore);GO:0000792(heterochromatin);GO:0005720(nuclear heterochromatin);GO:0010369(chromocenter);GO:0035097(histone methyltransferase complex);GO:0035097(histone methyltransferase complex)","NA","NA","NA","chromobox 5 [Source:HGNC Symbol;Acc:HGNC:1555]",{"v":3.01223269202128,"d":"3.01"},{"v":0.84222434268617,"d":"0.84"},{"v":3.57652057694526,"d":"3.58"},{"v":1.83855674186706,"d":"1.84"},{"v":0.0193374900455691,"d":"0.02"},{"v":0.359881845992299,"d":"0.36"},"up","yes"]
["ENSG00000144815","NXPE3","ENST00000273347;ENST00000477909;ENST00000616286;ENST00000491511;ENST00000495842;ENST00000487830;ENST00000474165","GO:0005576(extracellular region);GO:0005576(extracellular region)","NA","NA","NA","neurexophilin and PC-esterase domain family member 3 [Source:HGNC Symbol;Acc:HGNC:28238]",{"v":3.0842882671685,"d":"3.08"},{"v":0.85754839328315,"d":"0.86"},{"v":3.59663465213923,"d":"3.60"},{"v":1.84664761726678,"d":"1.85"},{"v":0.0193779478984223,"d":"0.02"},{"v":0.359949253004991,"d":"0.36"},"up","yes"]
["MSTRG.3130","CLEC2B","ENST00000228438;ENST00000540743;ENST00000538152;ENST00000539028","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0030246(carbohydrate binding);GO:0050776(regulation of immune response);GO:0005886(plasma membrane);GO:0005887(integral component of plasma membrane);GO:0005887(integral component of plasma membrane)","05167(Kaposi's sarcoma-associated herpesvirus infection);05167(Kaposi's sarcoma-associated herpesvirus infection)","K10071","NA","C-type lectin domain family 2 member B [Source:HGNC Symbol;Acc:HGNC:2053]",{"v":14.4614534128127,"d":"14.46"},{"v":35.507750747536,"d":"35.51"},{"v":0.407275963933486,"d":"0.41"},{"v":-1.29592142107438,"d":"-1.30"},{"v":0.0194031027625183,"d":"0.02"},{"v":0.359949253004991,"d":"0.36"},"down","yes"]
["MSTRG.12288","AC116366.1","ENST00000443093","NA","NA","NA","NA",null,{"v":1.972458,"d":"1.97"},{"v":0.542029,"d":"0.54"},{"v":3.63902669414367,"d":"3.64"},{"v":1.86355263413299,"d":"1.86"},{"v":0.0195549223761318,"d":"0.02"},{"v":0.361766733405991,"d":"0.36"},"up","yes"]
["MSTRG.11422","AC072022.1","ENST00000450760","NA","NA","NA","NA",null,{"v":4.155608,"d":"4.16"},{"v":1.122439,"d":"1.12"},{"v":3.70230186228383,"d":"3.70"},{"v":1.88842252823541,"d":"1.89"},{"v":0.0195775525418212,"d":"0.02"},{"v":0.361766733405991,"d":"0.36"},"up","yes"]
["MSTRG.12283","UQCRQ","ENST00000378670;ENST00000498309;ENST00000378667;ENST00000496429;ENST00000480372;ENST00000378665","GO:0016020(membrane);GO:0055114(oxidation-reduction process);GO:0005739(mitochondrion);GO:0005743(mitochondrial inner membrane);GO:1902600(hydrogen ion transmembrane transport);GO:0070469(respiratory chain);GO:0008121(ubiquinol-cytochrome-c reductase activity);GO:0006122(mitochondrial electron transport, ubiquinol to cytochrome c);GO:0005750(mitochondrial respiratory chain complex III);GO:0021539(subthalamus development);GO:0021548(pons development);GO:0021680(cerebellar Purkinje cell layer development);GO:0021766(hippocampus development);GO:0021794(thalamus development);GO:0021854(hypothalamus development);GO:0021860(pyramidal neuron development);GO:0030901(midbrain development);GO:0030901(midbrain development)","00190(Oxidative phosphorylation);04260(Cardiac muscle contraction);05010(Alzheimer's disease);05012(Parkinson's disease);05016(Huntington's disease);04932(Non-alcoholic fatty liver disease (NAFLD));04932(Non-alcoholic fatty liver disease (NAFLD))","K00418","NA","ubiquinol-cytochrome c reductase complex III subunit VII [Source:HGNC Symbol;Acc:HGNC:29594]",{"v":4.61305168274457,"d":"4.61"},{"v":11.4079146338315,"d":"11.41"},{"v":0.404372913964839,"d":"0.40"},{"v":-1.30624173018183,"d":"-1.31"},{"v":0.0195945298641495,"d":"0.02"},{"v":0.361766733405991,"d":"0.36"},"down","yes"]
["MSTRG.10416","MYH9","ENST00000216181;ENST00000459960;ENST00000472210;ENST00000495928;ENST00000463027;ENST00000401701;ENST00000473022;ENST00000456729;ENST00000486218;ENST00000475726;ENST00000477189","GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0015031(protein transport);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0003774(motor activity);GO:0016459(myosin complex);GO:0007155(cell adhesion);GO:0003779(actin binding);GO:0005829(cytosol);GO:0042803(protein homodimerization activity);GO:0005886(plasma membrane);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0019904(protein domain specific binding);GO:0000212(meiotic spindle organization);GO:0000904(cell morphogenesis involved in differentiation);GO:0001701(in utero embryonic development);GO:0001768(establishment of T cell polarity);GO:0006911(phagocytosis, engulfment);GO:0007520(myoblast fusion);GO:0008360(regulation of cell shape);GO:0016337(single organismal cell-cell adhesion);GO:0032796(uropod organization);GO:0051295(establishment of meiotic spindle localization);GO:1903919(negative regulation of actin filament severing);GO:1903923(positive regulation of protein processing in phagocytic vesicle);GO:0001725(stress fiber);GO:0001772(immunological synapse);GO:0001931(uropod);GO:0005819(spindle);GO:0005903(brush border);GO:0005913(cell-cell adherens junction);GO:0005925(focal adhesion);GO:0005938(cell cortex);GO:0016460(myosin II complex);GO:0030863(cortical cytoskeleton);GO:0031594(neuromuscular junction);GO:0007229(integrin-mediated signaling pathway);GO:0005516(calmodulin binding);GO:0045296(cadherin binding);GO:0051015(actin filament binding);GO:0031252(cell leading edge);GO:0070062(extracellular exosome);GO:0008180(COP9 signalosome);GO:0032154(cleavage furrow);GO:0043234(protein complex);GO:0016887(ATPase activity);GO:0031012(extracellular matrix);GO:0032506(cytokinetic process);GO:0001726(ruffle);GO:0070527(platelet aggregation);GO:0001525(angiogenesis);GO:0006509(membrane protein ectodomain proteolysis);GO:0015629(actin cytoskeleton);GO:0031532(actin cytoskeleton reorganization);GO:0000146(microfilament motor activity);GO:0030048(actin filament-based movement);GO:0043495(protein anchor);GO:0030898(actin-dependent ATPase activity);GO:0030220(platelet formation);GO:0008305(integrin complex);GO:0030224(monocyte differentiation);GO:0043531(ADP binding);GO:0031032(actomyosin structure organization);GO:0043534(blood vessel endothelial cell migration);GO:0050900(leukocyte migration);GO:0005826(actomyosin contractile ring);GO:0042641(actomyosin);GO:0097513(myosin II filament);GO:0097513(myosin II filament)","04530(Tight junction);04810(Regulation of actin cytoskeleton);05132(Salmonella infection);05132(Salmonella infection)","K10352","NA","myosin heavy chain 9 [Source:HGNC Symbol;Acc:HGNC:7579]",{"v":169.937485845518,"d":"169.94"},{"v":47.8545530128363,"d":"47.85"},{"v":3.55112471325215,"d":"3.55"},{"v":1.82827602778524,"d":"1.83"},{"v":0.0196988227623221,"d":"0.02"},{"v":0.363114966252137,"d":"0.36"},"up","yes"]
["MSTRG.2418","PATL1","ENST00000300146;ENST00000531919","GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016607(nuclear speck);GO:0005515(protein binding);GO:0000932(P-body);GO:0005829(cytosol);GO:0030014(CCR4-NOT complex);GO:0016605(PML body);GO:0043928(exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay);GO:0008266(poly(U) RNA binding);GO:0034046(poly(G) binding);GO:0000290(deadenylation-dependent decapping of nuclear-transcribed mRNA);GO:0033962(cytoplasmic mRNA processing body assembly);GO:0033962(cytoplasmic mRNA processing body assembly)","03018(RNA degradation);03018(RNA degradation)","K12617","NA","PAT1 homolog 1, processing body mRNA decay factor [Source:HGNC Symbol;Acc:HGNC:26721]",{"v":12.2399719289388,"d":"12.24"},{"v":3.43600366713417,"d":"3.44"},{"v":3.56226975134391,"d":"3.56"},{"v":1.83279676803721,"d":"1.83"},{"v":0.019730102809491,"d":"0.02"},{"v":0.363115188473248,"d":"0.36"},"up","yes"]
["ENSG00000130827","PLXNA3","ENST00000369682;ENST00000478236;ENST00000467463;ENST00000493546;ENST00000497802;ENST00000480645;ENST00000491066;ENST00000482598","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0043231(intracellular membrane-bounded organelle);GO:0005634(nucleus);GO:0007165(signal transduction);GO:0005886(plasma membrane);GO:0030054(cell junction);GO:0005515(protein binding);GO:0007275(multicellular organism development);GO:0017154(semaphorin receptor activity);GO:0071526(semaphorin-plexin signaling pathway);GO:0004888(transmembrane signaling receptor activity);GO:0002116(semaphorin receptor complex);GO:0021785(branchiomotor neuron axon guidance);GO:0048841(regulation of axon extension involved in axon guidance);GO:0007411(axon guidance);GO:0021612(facial nerve structural organization);GO:0021637(trigeminal nerve structural organization);GO:0021766(hippocampus development);GO:0021860(pyramidal neuron development);GO:0048843(negative regulation of axon extension involved in axon guidance);GO:0050919(negative chemotaxis);GO:0051495(positive regulation of cytoskeleton organization);GO:0097485(neuron projection guidance);GO:1902287(semaphorin-plexin signaling pathway involved in axon guidance);GO:1990138(neuron projection extension);GO:1990138(neuron projection extension)","04360(Axon guidance);04360(Axon guidance)","K06820","NA","plexin A3 [Source:HGNC Symbol;Acc:HGNC:9101]",{"v":0.877760377284372,"d":"0.88"},{"v":0.241081746370623,"d":"0.24"},{"v":3.64092425286717,"d":"3.64"},{"v":1.86430472673419,"d":"1.86"},{"v":0.0197705394551403,"d":"0.02"},{"v":0.363283662488204,"d":"0.36"},"up","yes"]
["MSTRG.6154","MAF","ENST00000393350;ENST00000569649;ENST00000326043","GO:0005634(nucleus);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0005515(protein binding);GO:0006366(transcription from RNA polymerase II promoter);GO:0001228(transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding);GO:0043565(sequence-specific DNA binding);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0001816(cytokine production);GO:0002088(lens development in camera-type eye);GO:0010628(positive regulation of gene expression);GO:0032330(regulation of chondrocyte differentiation);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0048468(cell development);GO:0048839(inner ear development);GO:0070306(lens fiber cell differentiation);GO:0000785(chromatin);GO:0005737(cytoplasm);GO:0005737(cytoplasm)","04658(Th1 and Th2 cell differentiation);05202(Transcriptional misregulation in cancers);05321(Inflammatiory bowel disease (IBD));05321(Inflammatiory bowel disease (IBD))","K09035","NA","MAF bZIP transcription factor [Source:HGNC Symbol;Acc:HGNC:6776]",{"v":3.60037707884174,"d":"3.60"},{"v":1.00602268262615,"d":"1.01"},{"v":3.57882296395466,"d":"3.58"},{"v":1.8394851787524,"d":"1.84"},{"v":0.0198356333431151,"d":"0.02"},{"v":0.363903965266345,"d":"0.36"},"up","yes"]
["ENSG00000007545","CRAMP1","ENST00000293925;ENST00000467286;ENST00000466562;ENST00000468839;ENST00000415022;ENST00000492778;ENST00000397412","GO:0005634(nucleus);GO:0003677(DNA binding);GO:0003682(chromatin binding);GO:0003682(chromatin binding)","NA","NA","NA","cramped chromatin regulator homolog 1 [Source:HGNC Symbol;Acc:HGNC:14122]",{"v":1.88976420601935,"d":"1.89"},{"v":0.526913482503284,"d":"0.53"},{"v":3.58647912564578,"d":"3.59"},{"v":1.84256823388935,"d":"1.84"},{"v":0.0200143196820076,"d":"0.02"},{"v":0.366602988118541,"d":"0.37"},"up","yes"]
["ENSG00000170522","ELOVL6","ENST00000514184;ENST00000302274;ENST00000394607;ENST00000513003;ENST00000507451","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016740(transferase activity);GO:0006629(lipid metabolic process);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0009922(fatty acid elongase activity);GO:0102336(3-oxo-arachidoyl-CoA synthase activity);GO:0102337(3-oxo-cerotoyl-CoA synthase activity);GO:0102338(3-oxo-lignoceronyl-CoA synthase activity);GO:0006631(fatty acid metabolic process);GO:0006633(fatty acid biosynthetic process);GO:0006636(unsaturated fatty acid biosynthetic process);GO:0019367(fatty acid elongation, saturated fatty acid);GO:0042761(very long-chain fatty acid biosynthetic process);GO:0034625(fatty acid elongation, monounsaturated fatty acid);GO:0035338(long-chain fatty-acyl-CoA biosynthetic process);GO:0016747(transferase activity, transferring acyl groups other than amino-acyl groups);GO:0030497(fatty acid elongation);GO:0030176(integral component of endoplasmic reticulum membrane);GO:0005515(protein binding);GO:0030148(sphingolipid biosynthetic process);GO:0045540(regulation of cholesterol biosynthetic process);GO:0034626(fatty acid elongation, polyunsaturated fatty acid);GO:0042759(long-chain fatty acid biosynthetic process);GO:0042759(long-chain fatty acid biosynthetic process)","00062(Fatty acid elongation);01040(Biosynthesis of unsaturated fatty acids);01040(Biosynthesis of unsaturated fatty acids)","K10203","EC:2.3.1.199","ELOVL fatty acid elongase 6 [Source:HGNC Symbol;Acc:HGNC:15829]",{"v":0.40084303138276,"d":"0.40"},{"v":0.104352720296012,"d":"0.10"},{"v":3.84123221939696,"d":"3.84"},{"v":1.94156918377145,"d":"1.94"},{"v":0.0201490687138173,"d":"0.02"},{"v":0.367974185600924,"d":"0.37"},"up","yes"]
["MSTRG.11538","BOD1L1","MSTRG.11538.2;ENST00000040738;ENST00000482713;ENST00000505343;ENST00000511119;ENST00000509897","GO:0005654(nucleoplasm);GO:0005694(chromosome);GO:0006281(DNA repair);GO:0006974(cellular response to DNA damage stimulus);GO:0031297(replication fork processing);GO:0031297(replication fork processing)","NA","NA","NA","biorientation of chromosomes in cell division 1 like 1 [Source:HGNC Symbol;Acc:HGNC:31792]",{"v":13.43929874029,"d":"13.44"},{"v":3.79648019773014,"d":"3.80"},{"v":3.53993647808967,"d":"3.54"},{"v":1.82372347229492,"d":"1.82"},{"v":0.0201525516268137,"d":"0.02"},{"v":0.367974185600924,"d":"0.37"},"up","yes"]
["MSTRG.8537","NCOA1","ENST00000288599;ENST00000395856;ENST00000348332;ENST00000407230;ENST00000405141;ENST00000406961;ENST00000493773;ENST00000486198;ENST00000496333;MSTRG.8537.5;ENST00000483904","GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0005634(nucleus);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0016740(transferase activity);GO:0003713(transcription coactivator activity);GO:0046983(protein dimerization activity);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0016746(transferase activity, transferring acyl groups);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0004402(histone acetyltransferase activity);GO:0030374(ligand-dependent nuclear receptor transcription coactivator activity);GO:0045893(positive regulation of transcription, DNA-templated);GO:0032870(cellular response to hormone stimulus);GO:0035257(nuclear hormone receptor binding);GO:0047485(protein N-terminus binding);GO:0019899(enzyme binding);GO:0000790(nuclear chromatin);GO:0017162(aryl hydrocarbon receptor binding);GO:0043234(protein complex);GO:0030521(androgen receptor signaling pathway);GO:0016922(ligand-dependent nuclear receptor binding);GO:0019216(regulation of lipid metabolic process);GO:0015721(bile acid and bile salt transport);GO:0050681(androgen receptor binding);GO:0001105(RNA polymerase II transcription coactivator activity);GO:0030522(intracellular receptor signaling pathway);GO:0001012(RNA polymerase II regulatory region DNA binding);GO:0003677(DNA binding);GO:0003682(chromatin binding);GO:0008134(transcription factor binding);GO:0030331(estrogen receptor binding);GO:0032403(protein complex binding);GO:0033142(progesterone receptor binding);GO:0042974(retinoic acid receptor binding);GO:0046965(retinoid X receptor binding);GO:0000435(positive regulation of transcription from RNA polymerase II promoter by galactose);GO:0002155(regulation of thyroid hormone mediated signaling pathway);GO:0007595(lactation);GO:0008584(male gonad development);GO:0009725(response to hormone);GO:0021549(cerebellum development);GO:0021766(hippocampus development);GO:0021854(hypothalamus development);GO:0021987(cerebral cortex development);GO:0032355(response to estradiol);GO:0032526(response to retinoic acid);GO:0032570(response to progesterone);GO:0043065(positive regulation of apoptotic process);GO:0043967(histone H4 acetylation);GO:0044849(estrous cycle);GO:0045666(positive regulation of neuron differentiation);GO:0045925(positive regulation of female receptivity);GO:0060179(male mating behavior);GO:0060713(labyrinthine layer morphogenesis);GO:1904017(cellular response to Thyroglobulin triiodothyronine);GO:2001038(regulation of cellular response to drug);GO:2001141(regulation of RNA biosynthetic process);GO:0005737(cytoplasm);GO:0043005(neuron projection);GO:0043005(neuron projection)","04919(Thyroid hormone signaling pathway);05200(Pathways in cancer);05224(Breast cancer);05224(Breast cancer)","K09101","EC:2.3.1.48","nuclear receptor coactivator 1 [Source:HGNC Symbol;Acc:HGNC:7668]",{"v":16.6990736304877,"d":"16.70"},{"v":4.72093274423723,"d":"4.72"},{"v":3.53724031567109,"d":"3.54"},{"v":1.82262423726032,"d":"1.82"},{"v":0.0202907741790433,"d":"0.02"},{"v":0.369916421571789,"d":"0.37"},"up","yes"]
["MSTRG.5388","ZNF592","ENST00000299927;ENST00000560079;ENST00000559607","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0005515(protein binding)","NA","NA","NA","zinc finger protein 592 [Source:HGNC Symbol;Acc:HGNC:28986]",{"v":11.3260842003934,"d":"11.33"},{"v":3.20489045893779,"d":"3.20"},{"v":3.53400041140478,"d":"3.53"},{"v":1.82130220783848,"d":"1.82"},{"v":0.020447958084114,"d":"0.02"},{"v":0.371703638791501,"d":"0.37"},"up","yes"]
["ENSG00000131263","RLIM","ENST00000332687;ENST00000349225","GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0016740(transferase activity);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0016567(protein ubiquitination);GO:0006511(ubiquitin-dependent protein catabolic process);GO:0061630(ubiquitin protein ligase activity);GO:0043161(proteasome-mediated ubiquitin-dependent protein catabolic process);GO:0003714(transcription corepressor activity);GO:0000209(protein polyubiquitination);GO:0004842(ubiquitin-protein transferase activity);GO:0045892(negative regulation of transcription, DNA-templated);GO:0017053(transcriptional repressor complex);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0043433(negative regulation of sequence-specific DNA binding transcription factor activity);GO:0060816(random inactivation of X chromosome);GO:1900095(regulation of dosage compensation by inactivation of X chromosome);GO:1900095(regulation of dosage compensation by inactivation of X chromosome)","NA","NA","NA","ring finger protein, LIM domain interacting [Source:HGNC Symbol;Acc:HGNC:13429]",{"v":0.645445796276405,"d":"0.65"},{"v":0.176962894020766,"d":"0.18"},{"v":3.64735104411586,"d":"3.65"},{"v":1.86684906044516,"d":"1.87"},{"v":0.0204702142140635,"d":"0.02"},{"v":0.371703638791501,"d":"0.37"},"up","yes"]
["MSTRG.14757","TLN1;MIR6852","MSTRG.14757.1;MSTRG.14757.3;ENST00000314888;ENST00000378192;MSTRG.14757.5;ENST00000465002;ENST00000495712;MSTRG.14757.4;ENST00000486788;ENST00000466916;ENST00000464379;ENST00000489255;ENST00000621699","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0003779(actin binding);GO:0051015(actin filament binding);GO:0007155(cell adhesion);GO:0005886(plasma membrane);GO:0005856(cytoskeleton);GO:0042995(cell projection);GO:0005515(protein binding);GO:0005200(structural constituent of cytoskeleton);GO:0030054(cell junction);GO:0005925(focal adhesion);GO:0005576(extracellular region);GO:0007016(cytoskeletal anchoring at plasma membrane);GO:0005829(cytosol);GO:0045296(cadherin binding);GO:0070062(extracellular exosome);GO:0032587(ruffle membrane);GO:0016032(viral process);GO:0070527(platelet aggregation);GO:0002576(platelet degranulation);GO:0009986(cell surface);GO:0005178(integrin binding);GO:0007043(cell-cell junction assembly);GO:0005911(cell-cell junction);GO:0036498(IRE1-mediated unfolded protein response);GO:0001726(ruffle);GO:0006936(muscle contraction);GO:0017166(vinculin binding);GO:0006928(movement of cell or subcellular component);GO:0030274(LIM domain binding);GO:0001786(phosphatidylserine binding);GO:0032403(protein complex binding);GO:0035091(phosphatidylinositol binding);GO:0007044(cell-substrate junction assembly);GO:0007229(integrin-mediated signaling pathway);GO:0030866(cortical actin cytoskeleton organization);GO:0033622(integrin activation);GO:0033622(integrin activation)","04015(Rap1 signaling pathway);04510(Focal adhesion);04611(Platelet activation);05166(HTLV-I infection);05166(HTLV-I infection)","K06271","NA","talin 1 [Source:HGNC Symbol;Acc:HGNC:11845];microRNA 6852 [Source:HGNC Symbol;Acc:HGNC:49993]",{"v":92.0287155327142,"d":"92.03"},{"v":26.1002806373829,"d":"26.10"},{"v":3.52596651397316,"d":"3.53"},{"v":1.81801877347992,"d":"1.82"},{"v":0.0204946804620154,"d":"0.02"},{"v":0.371703638791501,"d":"0.37"},"up","yes"]
["MSTRG.3171","KLRC4-KLRK1;KLRK1;KLRC4","MSTRG.3171.1;ENST00000240618;MSTRG.3171.2;ENST00000586581;ENST00000544449;ENST00000540818;ENST00000590323;ENST00000539300;ENST00000588447;ENST00000540267;ENST00000539370;ENST00000309384;ENST00000396451;ENST00000585711;ENST00000591546;MSTRG.3171.3;ENST00000590131;ENST00000543572","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0030246(carbohydrate binding);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0030154(cell differentiation);GO:0002376(immune system process);GO:0045087(innate immune response);GO:0032394(MHC class Ib receptor activity);GO:0042288(MHC class I protein binding);GO:0042803(protein homodimerization activity);GO:0002223(stimulatory C-type lectin receptor signaling pathway);GO:0030101(natural killer cell activation);GO:0032729(positive regulation of interferon-gamma production);GO:0045429(positive regulation of nitric oxide biosynthetic process);GO:0045954(positive regulation of natural killer cell mediated cytotoxicity);GO:0050830(defense response to Gram-positive bacterium);GO:0071222(cellular response to lipopolysaccharide);GO:0009897(external side of plasma membrane);GO:0009986(cell surface);GO:0002250(adaptive immune response);GO:0050776(regulation of immune response);GO:0004872(receptor activity);GO:0005887(integral component of plasma membrane);GO:0007165(signal transduction);GO:0031295(T cell costimulation);GO:0034260(negative regulation of GTPase activity);GO:0042267(natural killer cell mediated cytotoxicity);GO:2000502(negative regulation of natural killer cell chemotaxis);GO:0006968(cellular defense response);GO:0016021(integral component of membrane)","04650(Natural killer cell mediated cytotoxicity);05144(Malaria);04612(Antigen processing and presentation);05144(Malaria)","K06728;K06541","NA","killer cell lectin like receptor K1 [Source:HGNC Symbol;Acc:HGNC:18788];KLRC4-KLRK1 readthrough [Source:HGNC Symbol;Acc:HGNC:48357];killer cell lectin like receptor C4 [Source:HGNC Symbol;Acc:HGNC:6377]",{"v":8.12475476482285,"d":"8.12"},{"v":19.7380758291757,"d":"19.74"},{"v":0.41162851106354,"d":"0.41"},{"v":-1.28058518227298,"d":"-1.28"},{"v":0.0205168373775383,"d":"0.02"},{"v":0.371703638791501,"d":"0.37"},"down","yes"]
["ENSG00000275342","PRAG1","ENST00000615670;ENST00000622241","GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0004713(protein tyrosine kinase activity);GO:0018108(peptidyl-tyrosine phosphorylation);GO:0004715(non-membrane spanning protein tyrosine kinase activity);GO:0004715(non-membrane spanning protein tyrosine kinase activity)","NA","NA","NA","PEAK1 related kinase activating pseudokinase 1 [Source:HGNC Symbol;Acc:HGNC:25438]",{"v":3.31415905485318,"d":"3.31"},{"v":0.930411236337684,"d":"0.93"},{"v":3.56203679127789,"d":"3.56"},{"v":1.83270241770849,"d":"1.83"},{"v":0.02061809994037,"d":"0.02"},{"v":0.372417792364076,"d":"0.37"},"up","yes"]
["MSTRG.11421","BCL6","MSTRG.11421.4;ENST00000232014;ENST00000621333;ENST00000406870;ENST00000438077;ENST00000419510;ENST00000479110;ENST00000430339;ENST00000470319","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0005794(Golgi apparatus);GO:0046872(metal ion binding);GO:0005654(nucleoplasm);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0005515(protein binding);GO:0006974(cellular response to DNA damage stimulus);GO:0002376(immune system process);GO:0006954(inflammatory response);GO:0042802(identical protein binding);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0043065(positive regulation of apoptotic process);GO:0043565(sequence-specific DNA binding);GO:0030308(negative regulation of cell growth);GO:0042127(regulation of cell proliferation);GO:0042981(regulation of apoptotic process);GO:0045892(negative regulation of transcription, DNA-templated);GO:0005657(replication fork);GO:0045591(positive regulation of regulatory T cell differentiation);GO:0003682(chromatin binding);GO:0050727(regulation of inflammatory response);GO:0000060(protein import into nucleus, translocation);GO:0042092(type 2 immune response);GO:0050776(regulation of immune response);GO:0000977(RNA polymerase II regulatory region sequence-specific DNA binding);GO:0001161(intronic transcription regulatory region sequence-specific DNA binding);GO:0001227(transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding);GO:0031490(chromatin DNA binding);GO:0000902(cell morphogenesis);GO:0001953(negative regulation of cell-matrix adhesion);GO:0002467(germinal center formation);GO:0002634(regulation of germinal center formation);GO:0002829(negative regulation of type 2 immune response);GO:0002903(negative regulation of B cell apoptotic process);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0007266(Rho protein signal transduction);GO:0007283(spermatogenesis);GO:0008104(protein localization);GO:0008285(negative regulation of cell proliferation);GO:0030036(actin cytoskeleton organization);GO:0030183(B cell differentiation);GO:0030890(positive regulation of B cell proliferation);GO:0031065(positive regulation of histone deacetylation);GO:0032764(negative regulation of mast cell cytokine production);GO:0035024(negative regulation of Rho protein signal transduction);GO:0043066(negative regulation of apoptotic process);GO:0043087(regulation of GTPase activity);GO:0043380(regulation of memory T cell differentiation);GO:0045596(negative regulation of cell differentiation);GO:0045629(negative regulation of T-helper 2 cell differentiation);GO:0045666(positive regulation of neuron differentiation);GO:0045746(negative regulation of Notch signaling pathway);GO:0048294(negative regulation of isotype switching to IgE isotypes);GO:0048821(erythrocyte development);GO:0051272(positive regulation of cellular component movement);GO:1903464(negative regulation of mitotic cell cycle DNA replication);GO:2000773(negative regulation of cellular senescence);GO:2000773(negative regulation of cellular senescence)","04068(FoxO signaling pathway);05202(Transcriptional misregulation in cancers);05202(Transcriptional misregulation in cancers)","K15618","NA","B-cell CLL/lymphoma 6 [Source:HGNC Symbol;Acc:HGNC:1001]",{"v":22.6715505628322,"d":"22.67"},{"v":6.43171970521173,"d":"6.43"},{"v":3.52495935798649,"d":"3.52"},{"v":1.81760662364778,"d":"1.82"},{"v":0.0206203944278051,"d":"0.02"},{"v":0.372417792364076,"d":"0.37"},"up","yes"]
["MSTRG.8934","AC244205.1;IGKV1-5;IGKV1-33;IGKV1-16;IGKV2-30;IGKV3-15;IGKV1-12;IGKJ4;IGKV1-39;IGKJ5;IGKJ2;IGKV3-20;IGKV6-21;IGKV2-29;IGKJ3;IGKC;AC244205.2;IGKV1-13","MSTRG.8934.23;MSTRG.8934.18;MSTRG.8934.9;MSTRG.8934.6;MSTRG.8934.12;ENST00000468494;MSTRG.8934.26;MSTRG.8934.15;ENST00000390252;MSTRG.8934.13;ENST00000480492;MSTRG.8934.21;ENST00000390239;MSTRG.8934.24;ENST00000624935;ENST00000473726;MSTRG.8934.17;MSTRG.8934.27;ENST00000498574;ENST00000390238;ENST00000479981;ENST00000390241;ENST00000496168;MSTRG.8934.11;MSTRG.8934.29;MSTRG.8934.7;ENST00000521304;MSTRG.8934.5;MSTRG.8934.10;MSTRG.8934.14;ENST00000492167;MSTRG.8934.16;ENST00000390240;MSTRG.8934.19;ENST00000390256;ENST00000390237;MSTRG.8934.28;MSTRG.8934.8;MSTRG.8934.25;ENST00000434790;MSTRG.8934.20;ENST00000635781;MSTRG.8934.22;MSTRG.8934.4","GO:0016020(membrane);GO:0005886(plasma membrane);GO:0005576(extracellular region);GO:0006508(proteolysis);GO:0006955(immune response);GO:0002376(immune system process);GO:0003823(antigen binding);GO:0002250(adaptive immune response);GO:0004252(serine-type endopeptidase activity);GO:0006898(receptor-mediated endocytosis);GO:0006956(complement activation);GO:0006958(complement activation, classical pathway);GO:0030449(regulation of complement activation);GO:0038095(Fc-epsilon receptor signaling pathway);GO:0038096(Fc-gamma receptor signaling pathway involved in phagocytosis);GO:0050776(regulation of immune response);GO:0050900(leukocyte migration);GO:0070062(extracellular exosome);GO:0072562(blood microparticle);GO:0002377(immunoglobulin production);GO:0005615(extracellular space);GO:0019731(antibacterial humoral response);GO:0003094(glomerular filtration);GO:0071748(monomeric IgA immunoglobulin complex);GO:0071751(secretory IgA immunoglobulin complex);GO:0071756(pentameric IgM immunoglobulin complex);GO:0002250(adaptive immune response)","NA","NA","NA","immunoglobulin kappa variable 2-30 [Source:HGNC Symbol;Acc:HGNC:5785];immunoglobulin kappa variable 3-15 [Source:HGNC Symbol;Acc:HGNC:5816];immunoglobulin kappa variable 1-12 [Source:HGNC Symbol;Acc:HGNC:5730];immunoglobulin kappa joining 4 [Source:HGNC Symbol;Acc:HGNC:5722];immunoglobulin kappa variable 1-33 [Source:HGNC Symbol;Acc:HGNC:5737];immunoglobulin kappa variable 1-39 (gene/pseudogene) [Source:HGNC Symbol;Acc:HGNC:5740];immunoglobulin kappa joining 5 [Source:HGNC Symbol;Acc:HGNC:5723];immunoglobulin kappa variable 1-16 [Source:HGNC Symbol;Acc:HGNC:5732];immunoglobulin kappa joining 2 [Source:HGNC Symbol;Acc:HGNC:5720];immunoglobulin kappa variable 1-5 [Source:HGNC Symbol;Acc:HGNC:5741];immunoglobulin kappa variable 2-29 (gene/pseudogene) [Source:HGNC Symbol;Acc:HGNC:5784];immunoglobulin kappa variable 3-20 [Source:HGNC Symbol;Acc:HGNC:5817];immunoglobulin kappa joining 3 [Source:HGNC Symbol;Acc:HGNC:5721];immunoglobulin kappa variable 6-21 (non-functional) [Source:HGNC Symbol;Acc:HGNC:5836];immunoglobulin kappa constant [Source:HGNC Symbol;Acc:HGNC:5716]",{"v":22.3420433636879,"d":"22.34"},{"v":54.1751909701175,"d":"54.18"},{"v":0.412403592190594,"d":"0.41"},{"v":-1.2778711957095,"d":"-1.28"},{"v":0.0206774906310779,"d":"0.02"},{"v":0.372869097358241,"d":"0.37"},"down","yes"]
["MSTRG.3470","BAZ2A","ENST00000549884;ENST00000551812;ENST00000551996;ENST00000551759;ENST00000549506;ENST00000547453;ENST00000549763;ENST00000549327;ENST00000379441;ENST00000553222;ENST00000547650;ENST00000551959;ENST00000548578;ENST00000547647;ENST00000546695;ENST00000550730;ENST00000549787","GO:0005634(nucleus);GO:0016607(nuclear speck);GO:0046872(metal ion binding);GO:0005829(cytosol);GO:0003677(DNA binding);GO:0003723(RNA binding);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0016569(covalent chromatin modification);GO:0005515(protein binding);GO:0005730(nucleolus);GO:0042393(histone binding);GO:0006338(chromatin remodeling);GO:0016922(ligand-dependent nuclear receptor binding);GO:0070577(lysine-acetylated histone binding);GO:0000183(chromatin silencing at rDNA);GO:0005677(chromatin silencing complex);GO:0033553(rDNA heterochromatin);GO:0001164(RNA polymerase I CORE element sequence-specific DNA binding);GO:0016575(histone deacetylation);GO:0006306(DNA methylation);GO:0006306(DNA methylation)","NA","NA","NA","bromodomain adjacent to zinc finger domain 2A [Source:HGNC Symbol;Acc:HGNC:962]",{"v":13.803603171002,"d":"13.80"},{"v":3.91462948516212,"d":"3.91"},{"v":3.52615827968463,"d":"3.53"},{"v":1.81809723478034,"d":"1.82"},{"v":0.020726543973419,"d":"0.02"},{"v":0.373174194051651,"d":"0.37"},"up","yes"]
["MSTRG.4089","ARGLU1","MSTRG.4089.2;ENST00000400198;ENST00000360629;ENST00000375926;ENST00000472226","GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0005739(mitochondrion);GO:0005515(protein binding);GO:0045296(cadherin binding);GO:0045296(cadherin binding)","NA","NA","NA","arginine and glutamate rich 1 [Source:HGNC Symbol;Acc:HGNC:25482]",{"v":8.83490633098107,"d":"8.83"},{"v":21.391882344062,"d":"21.39"},{"v":0.413002754450614,"d":"0.41"},{"v":-1.27577669140489,"d":"-1.28"},{"v":0.0208864233813228,"d":"0.02"},{"v":0.374866076430942,"d":"0.37"},"down","yes"]
["MSTRG.8953","IGKV2-24","ENST00000484817","GO:0016020(membrane);GO:0005886(plasma membrane);GO:0005576(extracellular region);GO:0002376(immune system process);GO:0002377(immunoglobulin production);GO:0006955(immune response);GO:0005615(extracellular space);GO:0003823(antigen binding);GO:0002250(adaptive immune response)","NA","NA","NA","immunoglobulin kappa variable 2-24 [Source:HGNC Symbol;Acc:HGNC:5781]",{"v":3.136314,"d":"3.14"},{"v":7.889787,"d":"7.89"},{"v":0.397515674377521,"d":"0.40"},{"v":-1.33091634668941,"d":"-1.33"},{"v":0.0209004211855196,"d":"0.02"},{"v":0.374866076430942,"d":"0.37"},"down","yes"]
["MSTRG.5967","ZNF319","ENST00000299237;ENST00000562909","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0003677(DNA binding)","NA","NA","NA","zinc finger protein 319 [Source:HGNC Symbol;Acc:HGNC:13644]",{"v":0.892701996022461,"d":"0.89"},{"v":2.19699000842302,"d":"2.20"},{"v":0.406329565723986,"d":"0.41"},{"v":-1.29927775180123,"d":"-1.30"},{"v":0.0209476607849944,"d":"0.02"},{"v":0.374866076430942,"d":"0.37"},"down","yes"]
["ENSG00000140807","NKD1","ENST00000268459;ENST00000564336","GO:0090090(negative regulation of canonical Wnt signaling pathway);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0046872(metal ion binding);GO:0005509(calcium ion binding);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0016055(Wnt signaling pathway);GO:0045732(positive regulation of protein catabolic process);GO:2000096(positive regulation of Wnt signaling pathway, planar cell polarity pathway);GO:0000159(protein phosphatase type 2A complex);GO:0030165(PDZ domain binding);GO:0001754(eye photoreceptor cell differentiation);GO:0007525(somatic muscle development);GO:0030178(negative regulation of Wnt signaling pathway);GO:0090249(regulation of cell motility involved in somitogenic axis elongation);GO:1901231(positive regulation of non-canonical Wnt signaling pathway via JNK cascade);GO:1901233(negative regulation of convergent extension involved in axis elongation);GO:1901233(negative regulation of convergent extension involved in axis elongation)","04310(Wnt signaling pathway);04390(Hippo signaling pathway);04390(Hippo signaling pathway)","K03213","NA","naked cuticle homolog 1 [Source:HGNC Symbol;Acc:HGNC:17045]",{"v":0.179190703873745,"d":"0.18"},{"v":0.0481227210903874,"d":"0.05"},{"v":3.72361952552884,"d":"3.72"},{"v":1.89670566777449,"d":"1.90"},{"v":0.0209878652462613,"d":"0.02"},{"v":0.374866076430942,"d":"0.37"},"up","yes"]
["MSTRG.5664","TNFRSF17","ENST00000053243;ENST00000396495","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0007165(signal transduction);GO:0005886(plasma membrane);GO:0004872(receptor activity);GO:0002376(immune system process);GO:0002250(adaptive immune response);GO:0033209(tumor necrosis factor-mediated signaling pathway);GO:0012505(endomembrane system);GO:0007275(multicellular organism development);GO:0008283(cell proliferation);GO:0002260(lymphocyte homeostasis);GO:0002260(lymphocyte homeostasis)","04060(Cytokine-cytokine receptor interaction);04672(Intestinal immune network for IgA production);04672(Intestinal immune network for IgA production)","K05153","NA","TNF receptor superfamily member 17 [Source:HGNC Symbol;Acc:HGNC:11913]",{"v":0.890794704830054,"d":"0.89"},{"v":2.29109353846154,"d":"2.29"},{"v":0.388807654456666,"d":"0.39"},{"v":-1.36287147332543,"d":"-1.36"},{"v":0.021032091392714,"d":"0.02"},{"v":0.374866076430942,"d":"0.37"},"down","yes"]
["MSTRG.7212","SLC25A19","ENST00000584438;ENST00000580994;ENST00000580273;ENST00000579228;ENST00000402418;ENST00000581988;ENST00000579207;ENST00000416858;ENST00000375261;ENST00000320362;ENST00000580151","GO:0006810(transport);GO:0005634(nucleus);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0055085(transmembrane transport);GO:0005743(mitochondrial inner membrane);GO:0005739(mitochondrion);GO:0071934(thiamine transmembrane transport);GO:0006839(mitochondrial transport);GO:0042723(thiamine-containing compound metabolic process);GO:0031305(integral component of mitochondrial inner membrane);GO:0015234(thiamine transmembrane transporter activity);GO:0030233(deoxynucleotide transmembrane transporter activity);GO:0090422(thiamine pyrophosphate transporter activity);GO:0030302(deoxynucleotide transport);GO:0030974(thiamine pyrophosphate transport);GO:0030974(thiamine pyrophosphate transport)","NA","NA","NA","solute carrier family 25 member 19 [Source:HGNC Symbol;Acc:HGNC:14409]",{"v":0.763115503618818,"d":"0.76"},{"v":1.91325545657419,"d":"1.91"},{"v":0.398857089886589,"d":"0.40"},{"v":-1.32605617210837,"d":"-1.33"},{"v":0.0210605746230053,"d":"0.02"},{"v":0.374866076430942,"d":"0.37"},"down","yes"]
["MSTRG.8932","MAL","ENST00000309988;ENST00000489399;ENST00000354078;ENST00000353004","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005783(endoplasmic reticulum);GO:0005515(protein binding);GO:0006915(apoptotic process);GO:0030154(cell differentiation);GO:0045121(membrane raft);GO:0019911(structural constituent of myelin sheath);GO:0042552(myelination);GO:1902043(positive regulation of extrinsic apoptotic signaling pathway via death domain receptors);GO:0019898(extrinsic component of membrane);GO:0008289(lipid binding);GO:0016324(apical plasma membrane);GO:0016505(peptidase activator activity involved in apoptotic process);GO:0007417(central nervous system development);GO:0001766(membrane raft polarization);GO:0045176(apical protein localization);GO:0045176(apical protein localization)","NA","NA","NA","mal, T-cell differentiation protein [Source:HGNC Symbol;Acc:HGNC:6817]",{"v":3.70659894921071,"d":"3.71"},{"v":9.03446193548387,"d":"9.03"},{"v":0.410273348394178,"d":"0.41"},{"v":-1.28534265595888,"d":"-1.29"},{"v":0.0210873900460284,"d":"0.02"},{"v":0.374866076430942,"d":"0.37"},"down","yes"]
["ENSG00000198169","ZNF251","ENST00000530353;ENST00000524394;ENST00000525191;ENST00000292562","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0005622(intracellular);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding)","NA","NA","NA","zinc finger protein 251 [Source:HGNC Symbol;Acc:HGNC:13045]",{"v":0.888189859485726,"d":"0.89"},{"v":0.241578305729905,"d":"0.24"},{"v":3.67661266934607,"d":"3.68"},{"v":1.87837719681661,"d":"1.88"},{"v":0.0211070152733,"d":"0.02"},{"v":0.374866076430942,"d":"0.37"},"up","yes"]
["MSTRG.1482","LYST","ENST00000389793;ENST00000473037;ENST00000468107;ENST00000461526;ENST00000489585;ENST00000475277;ENST00000462376;ENST00000487530;ENST00000492844;ENST00000468626;ENST00000465349","GO:0006810(transport);GO:0005737(cytoplasm);GO:0015031(protein transport);GO:0042742(defense response to bacterium);GO:0051607(defense response to virus);GO:0007040(lysosome organization);GO:0005515(protein binding);GO:0015630(microtubule cytoskeleton);GO:0032438(melanosome organization);GO:0032510(endosome to lysosome transport via multivesicular body sorting pathway);GO:0030595(leukocyte chemotaxis);GO:0042832(defense response to protozoan);GO:0042267(natural killer cell mediated cytotoxicity);GO:0033364(mast cell secretory granule organization);GO:0043473(pigmentation);GO:0043473(pigmentation)","NA","NA","NA","lysosomal trafficking regulator [Source:HGNC Symbol;Acc:HGNC:1968]",{"v":17.2390376882329,"d":"17.24"},{"v":4.91540266095646,"d":"4.92"},{"v":3.50714659150192,"d":"3.51"},{"v":1.8102977335314,"d":"1.81"},{"v":0.0211415498062803,"d":"0.02"},{"v":0.374866076430942,"d":"0.37"},"up","yes"]
["MSTRG.5005","ZNF106","MSTRG.5005.2;MSTRG.5005.1;ENST00000564754;ENST00000565611;ENST00000263805;ENST00000565948;ENST00000565380;ENST00000565500;ENST00000567772;ENST00000570078","GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0005730(nucleolus);GO:0016020(membrane);GO:0005829(cytosol);GO:0008286(insulin receptor signaling pathway);GO:0017124(SH3 domain binding);GO:0017124(SH3 domain binding)","NA","NA","NA","zinc finger protein 106 [Source:HGNC Symbol;Acc:HGNC:12886]",{"v":11.915333539463,"d":"11.92"},{"v":3.39245682419537,"d":"3.39"},{"v":3.51230219187509,"d":"3.51"},{"v":1.81241697698147,"d":"1.81"},{"v":0.0211496994945126,"d":"0.02"},{"v":0.374866076430942,"d":"0.37"},"up","yes"]
["MSTRG.12618","AC138035.1","ENST00000499986;MSTRG.12618.2","NA","NA","NA","NA",null,{"v":2.09586290168387,"d":"2.10"},{"v":0.56725074741988,"d":"0.57"},{"v":3.69477327481159,"d":"3.69"},{"v":1.88548583789222,"d":"1.89"},{"v":0.0211755916764572,"d":"0.02"},{"v":0.374866076430942,"d":"0.37"},"up","yes"]
["ENSG00000110944","IL23A","ENST00000228534;ENST00000619177","GO:0042531(positive regulation of tyrosine phosphorylation of STAT protein);GO:0042104(positive regulation of activated T cell proliferation);GO:0050729(positive regulation of inflammatory response);GO:2000318(positive regulation of T-helper 17 type immune response);GO:0005576(extracellular region);GO:0005515(protein binding);GO:0006955(immune response);GO:0005125(cytokine activity);GO:0005615(extracellular space);GO:0002376(immune system process);GO:0045087(innate immune response);GO:0006954(inflammatory response);GO:0051607(defense response to virus);GO:0035722(interleukin-12-mediated signaling pathway);GO:0032729(positive regulation of interferon-gamma production);GO:0032733(positive regulation of interleukin-10 production);GO:0032735(positive regulation of interleukin-12 production);GO:0032760(positive regulation of tumor necrosis factor production);GO:0042346(positive regulation of NF-kappaB import into nucleus);GO:0050829(defense response to Gram-negative bacterium);GO:0005788(endoplasmic reticulum lumen);GO:0045672(positive regulation of osteoclast differentiation);GO:0048771(tissue remodeling);GO:0032740(positive regulation of interleukin-17 production);GO:0010536(positive regulation of activation of Janus kinase activity);GO:0032725(positive regulation of granulocyte macrophage colony-stimulating factor production);GO:0042102(positive regulation of T cell proliferation);GO:0043382(positive regulation of memory T cell differentiation);GO:0051135(positive regulation of NK T cell activation);GO:0045519(interleukin-23 receptor binding);GO:0001916(positive regulation of T cell mediated cytotoxicity);GO:0002230(positive regulation of defense response to virus by host);GO:0002827(positive regulation of T-helper 1 type immune response);GO:0032693(negative regulation of interleukin-10 production);GO:0032816(positive regulation of natural killer cell activation);GO:0032819(positive regulation of natural killer cell proliferation);GO:0034105(positive regulation of tissue remodeling);GO:0042509(regulation of tyrosine phosphorylation of STAT protein);GO:0051142(positive regulation of NK T cell proliferation);GO:2000330(positive regulation of T-helper 17 cell lineage commitment);GO:0070743(interleukin-23 complex);GO:0042098(T cell proliferation);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0090023(positive regulation of neutrophil chemotaxis);GO:0090023(positive regulation of neutrophil chemotaxis)","04630(Jak-STAT signaling pathway);04060(Cytokine-cytokine receptor interaction);04659(Th17 cell differentiation);05200(Pathways in cancer);05323(Rheumatoid arthritis);05321(Inflammatiory bowel disease (IBD));05133(Pertussis);05152(Tuberculosis);05152(Tuberculosis)","K05426","NA","interleukin 23 subunit alpha [Source:HGNC Symbol;Acc:HGNC:15488]",{"v":1.6761828357203,"d":"1.68"},{"v":4.13726147093513,"d":"4.14"},{"v":0.405143075315817,"d":"0.41"},{"v":-1.30349661257653,"d":"-1.30"},{"v":0.02129026183376,"d":"0.02"},{"v":0.375611106074782,"d":"0.38"},"down","yes"]
["MSTRG.389","AK2","ENST00000373449;ENST00000354858;ENST00000550338;ENST00000491241;ENST00000482191;ENST00000466029;ENST00000629371;ENST00000487289;ENST00000469238;ENST00000480134;ENST00000548033;ENST00000551979","GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0006139(nucleobase-containing compound metabolic process);GO:0005739(mitochondrion);GO:0019205(nucleobase-containing compound kinase activity);GO:0004017(adenylate kinase activity);GO:0016776(phosphotransferase activity, phosphate group as acceptor);GO:0006172(ADP biosynthetic process);GO:0046939(nucleotide phosphorylation);GO:0005758(mitochondrial intermembrane space);GO:0070062(extracellular exosome);GO:0015949(nucleobase-containing small molecule interconversion);GO:0046033(AMP metabolic process);GO:0046034(ATP metabolic process);GO:0005743(mitochondrial inner membrane);GO:0036126(sperm flagellum);GO:0097226(sperm mitochondrial sheath);GO:0097226(sperm mitochondrial sheath)","00230(Purine metabolism);00730(Thiamine metabolism);00730(Thiamine metabolism)","K00939","EC:2.7.4.3","adenylate kinase 2 [Source:HGNC Symbol;Acc:HGNC:362]",{"v":4.40772630050637,"d":"4.41"},{"v":10.6577558472149,"d":"10.66"},{"v":0.413569832495103,"d":"0.41"},{"v":-1.27379714157743,"d":"-1.27"},{"v":0.0213110732301719,"d":"0.02"},{"v":0.375611106074782,"d":"0.38"},"down","yes"]
["MSTRG.2201","MRPL17","ENST00000288937;ENST00000532676;ENST00000529958","GO:0030529(intracellular ribonucleoprotein complex);GO:0005622(intracellular);GO:0003735(structural constituent of ribosome);GO:0006412(translation);GO:0005840(ribosome);GO:0005739(mitochondrion);GO:0019904(protein domain specific binding);GO:0005743(mitochondrial inner membrane);GO:0070125(mitochondrial translational elongation);GO:0070126(mitochondrial translational termination);GO:0005762(mitochondrial large ribosomal subunit);GO:0000002(mitochondrial genome maintenance);GO:0000002(mitochondrial genome maintenance)","03010(Ribosome);03010(Ribosome)","K02879","NA","mitochondrial ribosomal protein L17 [Source:HGNC Symbol;Acc:HGNC:14053]",{"v":0.991307259226714,"d":"0.99"},{"v":2.45581296616872,"d":"2.46"},{"v":0.403657474279582,"d":"0.40"},{"v":-1.30879648943523,"d":"-1.31"},{"v":0.021314709282983,"d":"0.02"},{"v":0.375611106074782,"d":"0.38"},"down","yes"]
["MSTRG.11786","RPL34","ENST00000394668;MSTRG.11786.1;ENST00000502534;ENST00000394667;ENST00000503574;ENST00000394665;ENST00000506397;ENST00000504231","GO:0006412(translation);GO:0030529(intracellular ribonucleoprotein complex);GO:0005622(intracellular);GO:0003735(structural constituent of ribosome);GO:0005840(ribosome);GO:0005829(cytosol);GO:0045296(cadherin binding);GO:0070062(extracellular exosome);GO:0042254(ribosome biogenesis);GO:0006413(translational initiation);GO:0003723(RNA binding);GO:0006364(rRNA processing);GO:0000184(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay);GO:0019083(viral transcription);GO:0006614(SRP-dependent cotranslational protein targeting to membrane);GO:0022625(cytosolic large ribosomal subunit);GO:0005739(mitochondrion);GO:0005739(mitochondrion)","03010(Ribosome);03010(Ribosome)","K02915","NA","ribosomal protein L34 [Source:HGNC Symbol;Acc:HGNC:10340]",{"v":47.6601308710983,"d":"47.66"},{"v":114.810166258092,"d":"114.81"},{"v":0.41512117284073,"d":"0.42"},{"v":-1.2683955778499,"d":"-1.27"},{"v":0.0213872880740736,"d":"0.02"},{"v":0.376319055157904,"d":"0.38"},"down","yes"]
["MSTRG.10960","CYB561D2;Z84492.1","ENST00000425346;ENST00000418577;ENST00000419046;ENST00000607121;ENST00000490926;ENST00000607362;ENST00000606259;ENST00000232508;ENST00000607088;ENST00000606589;ENST00000607583","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0046872(metal ion binding);GO:0055114(oxidation-reduction process);GO:0016021(integral component of membrane)","NA","NA","NA","cytochrome b561 family member D2 [Source:HGNC Symbol;Acc:HGNC:30253];cytochrome b561 family member D2 [Source:NCBI gene;Acc:11068]",{"v":1.50814724178832,"d":"1.51"},{"v":3.68295644555961,"d":"3.68"},{"v":0.409493640253778,"d":"0.41"},{"v":-1.2880870489932,"d":"-1.29"},{"v":0.021481980074764,"d":"0.02"},{"v":0.377263354670744,"d":"0.38"},"down","yes"]
["MSTRG.14266","EXTL3","ENST00000220562;ENST00000523271;ENST00000522725;ENST00000520679;ENST00000523149;ENST00000520940;ENST00000519886;ENST00000517738;ENST00000521473","GO:0016021(integral component of membrane);GO:0016757(transferase activity, transferring glycosyl groups);GO:0016020(membrane);GO:0046872(metal ion binding);GO:0016740(transferase activity);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0036498(IRE1-mediated unfolded protein response);GO:0001888(glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity);GO:0004872(receptor activity);GO:0015012(heparan sulfate proteoglycan biosynthetic process);GO:0030307(positive regulation of cell growth);GO:0030307(positive regulation of cell growth)","00534(Glycosaminoglycan biosynthesis - heparan sulfate / heparin);00534(Glycosaminoglycan biosynthesis - heparan sulfate / heparin)","K02370","EC:2.4.1.223;EC:2.4.1.224","exostosin like glycosyltransferase 3 [Source:HGNC Symbol;Acc:HGNC:3518]",{"v":4.80676275869894,"d":"4.81"},{"v":1.3706282214826,"d":"1.37"},{"v":3.5069778101457,"d":"3.51"},{"v":1.81022830219208,"d":"1.81"},{"v":0.0215059279076925,"d":"0.02"},{"v":0.377263354670744,"d":"0.38"},"up","yes"]
["MSTRG.14926","AKNA;AL138895.1","ENST00000374088;MSTRG.14926.1;ENST00000492875;MSTRG.14926.8;ENST00000307564;MSTRG.14926.9;ENST00000312033;ENST00000490767;ENST00000448674;ENST00000223791;ENST00000374075;ENST00000374079","GO:0005634(nucleus);GO:0016020(membrane);GO:0043231(intracellular membrane-bounded organelle);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0006366(transcription from RNA polymerase II promoter);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0001650(fibrillar center);GO:0005813(centrosome);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0001077(transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0001077(transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding)","NA","NA","NA","AT-hook transcription factor [Source:HGNC Symbol;Acc:HGNC:24108]",{"v":38.589614744793,"d":"38.59"},{"v":11.0467130230749,"d":"11.05"},{"v":3.49331196204565,"d":"3.49"},{"v":1.80459548498859,"d":"1.80"},{"v":0.0216281238958755,"d":"0.02"},{"v":0.378834695026852,"d":"0.38"},"up","yes"]
["ENSG00000110046","ATG2A","ENST00000418259;ENST00000377264;ENST00000472525;ENST00000461701;ENST00000461955","GO:0043231(intracellular membrane-bounded organelle);GO:0006914(autophagy);GO:0005634(nucleus);GO:0005829(cytosol);GO:0016020(membrane);GO:0005515(protein binding);GO:0034045(pre-autophagosomal structure membrane);GO:0000045(autophagosome assembly);GO:0000422(mitophagy);GO:0044804(nucleophagy);GO:0019898(extrinsic component of membrane);GO:0000407(pre-autophagosomal structure);GO:0005811(lipid particle);GO:0005811(lipid particle)","04140(Autophagy - animal);04136(Autophagy - other eukaryotes);04136(Autophagy - other eukaryotes)","K17906","NA","autophagy related 2A [Source:HGNC Symbol;Acc:HGNC:29028]",{"v":6.62237430419314,"d":"6.62"},{"v":1.89185927407878,"d":"1.89"},{"v":3.50045819735605,"d":"3.50"},{"v":1.80754377799693,"d":"1.81"},{"v":0.0217644256596438,"d":"0.02"},{"v":0.380576950795691,"d":"0.38"},"up","yes"]
["MSTRG.14359","LYPLA1","ENST00000316963;ENST00000519926;ENST00000519272;ENST00000521856;ENST00000520896;ENST00000518546;ENST00000618914;ENST00000519891;ENST00000521898;ENST00000521352;ENST00000517297;ENST00000520718;ENST00000618741;ENST00000343231","GO:0005737(cytoplasm);GO:0016787(hydrolase activity);GO:0006629(lipid metabolic process);GO:0006631(fatty acid metabolic process);GO:0005515(protein binding);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0050999(regulation of nitric-oxide synthase activity);GO:0004622(lysophospholipase activity);GO:0008474(palmitoyl-(protein) hydrolase activity);GO:0016298(lipase activity);GO:0002084(protein depalmitoylation);GO:0042997(negative regulation of Golgi to plasma membrane protein transport);GO:0005739(mitochondrion);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016021(integral component of membrane)","00564(Glycerophospholipid metabolism);05231(Choline metabolism in cancer);05231(Choline metabolism in cancer)","K06128","EC:3.1.1.5","lysophospholipase I [Source:HGNC Symbol;Acc:HGNC:6737]",{"v":3.40021763570516,"d":"3.40"},{"v":8.20466053472518,"d":"8.20"},{"v":0.414425145478496,"d":"0.41"},{"v":-1.27081655287512,"d":"-1.27"},{"v":0.0217933393503053,"d":"0.02"},{"v":0.380576950795691,"d":"0.38"},"down","yes"]
["ENSG00000136319","TTC5","ENST00000258821;ENST00000557379;ENST00000553828;ENST00000554157","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005654(nucleoplasm);GO:0005515(protein binding);GO:0006281(DNA repair);GO:0006974(cellular response to DNA damage stimulus);GO:1901796(regulation of signal transduction by p53 class mediator);GO:0003677(DNA binding);GO:0003682(chromatin binding);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0045944(positive regulation of transcription from RNA polymerase II promoter)","NA","NA","NA","tetratricopeptide repeat domain 5 [Source:HGNC Symbol;Acc:HGNC:19274]",{"v":0.539950634724369,"d":"0.54"},{"v":1.31160463915507,"d":"1.31"},{"v":0.411671793927325,"d":"0.41"},{"v":-1.28043349042345,"d":"-1.28"},{"v":0.0218285614298136,"d":"0.02"},{"v":0.380576950795691,"d":"0.38"},"down","yes"]
["MSTRG.2469","UQCC3","ENST00000377953;ENST00000531323","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005743(mitochondrial inner membrane);GO:0005739(mitochondrion);GO:0031305(integral component of mitochondrial inner membrane);GO:0006754(ATP biosynthetic process);GO:0070300(phosphatidic acid binding);GO:1901612(cardiolipin binding);GO:0042407(cristae formation);GO:0006122(mitochondrial electron transport, ubiquinol to cytochrome c);GO:0005750(mitochondrial respiratory chain complex III);GO:0034551(mitochondrial respiratory chain complex III assembly);GO:0097033(mitochondrial respiratory chain complex III biogenesis);GO:0097033(mitochondrial respiratory chain complex III biogenesis)","NA","NA","NA","ubiquinol-cytochrome c reductase complex assembly factor 3 [Source:HGNC Symbol;Acc:HGNC:34399]",{"v":0.495102972477064,"d":"0.50"},{"v":1.24793119266055,"d":"1.25"},{"v":0.396738999224404,"d":"0.40"},{"v":-1.33373787430813,"d":"-1.33"},{"v":0.0218766961942981,"d":"0.02"},{"v":0.380576950795691,"d":"0.38"},"down","yes"]
["MSTRG.4404","CNIH1","ENST00000216416;ENST00000556113;ENST00000553660;ENST00000557690;ENST00000557659","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005794(Golgi apparatus);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0000139(Golgi membrane);GO:0016192(vesicle-mediated transport);GO:0006955(immune response);GO:0007165(signal transduction);GO:0006888(ER to Golgi vesicle-mediated transport);GO:0048208(COPII vesicle coating);GO:0012507(ER to Golgi transport vesicle membrane);GO:0033116(endoplasmic reticulum-Golgi intermediate compartment membrane);GO:0033116(endoplasmic reticulum-Golgi intermediate compartment membrane)","NA","NA","NA","cornichon family AMPA receptor auxiliary protein 1 [Source:HGNC Symbol;Acc:HGNC:19431]",{"v":1.8295388944664,"d":"1.83"},{"v":4.42700122351779,"d":"4.43"},{"v":0.413268215230492,"d":"0.41"},{"v":-1.27484968566971,"d":"-1.27"},{"v":0.0218914495075796,"d":"0.02"},{"v":0.380576950795691,"d":"0.38"},"down","yes"]
["MSTRG.15454","AL009174.1","ENST00000426577","NA","NA","NA","NA",null,{"v":3.081728,"d":"3.08"},{"v":7.725605,"d":"7.73"},{"v":0.398897950387057,"d":"0.40"},{"v":-1.32590838428261,"d":"-1.33"},{"v":0.0219804039370846,"d":"0.02"},{"v":0.381056727889526,"d":"0.38"},"down","yes"]
["ENSG00000170430","MGMT","ENST00000306010;ENST00000482547","GO:0043066(negative regulation of apoptotic process);GO:0005634(nucleus);GO:0016020(membrane);GO:0046872(metal ion binding);GO:0005654(nucleoplasm);GO:0008168(methyltransferase activity);GO:0016740(transferase activity);GO:0032259(methylation);GO:0003824(catalytic activity);GO:0003677(DNA binding);GO:0006281(DNA repair);GO:0006974(cellular response to DNA damage stimulus);GO:0003908(methylated-DNA-[protein]-cysteine S-methyltransferase activity);GO:0005509(calcium ion binding);GO:0006307(DNA dealkylation involved in DNA repair);GO:0009636(response to toxic substance);GO:0014070(response to organic cyclic compound);GO:0034599(cellular response to oxidative stress);GO:0042493(response to drug);GO:0043281(regulation of cysteine-type endopeptidase activity involved in apoptotic process);GO:0045471(response to ethanol);GO:0045739(positive regulation of DNA repair);GO:0051593(response to folic acid);GO:0060548(negative regulation of cell death);GO:0060644(mammary gland epithelial cell differentiation);GO:0071407(cellular response to organic cyclic compound);GO:0071479(cellular response to ionizing radiation);GO:0006266(DNA ligation);GO:0009008(DNA-methyltransferase activity);GO:0006306(DNA methylation);GO:2000781(positive regulation of double-strand break repair);GO:2000781(positive regulation of double-strand break repair)","NA","NA","NA","O-6-methylguanine-DNA methyltransferase [Source:HGNC Symbol;Acc:HGNC:7059]",{"v":1.21607231177959,"d":"1.22"},{"v":2.9447181217318,"d":"2.94"},{"v":0.412967306719467,"d":"0.41"},{"v":-1.27590052220306,"d":"-1.28"},{"v":0.0219846730117956,"d":"0.02"},{"v":0.381056727889526,"d":"0.38"},"down","yes"]
["ENSG00000103222","ABCC1","ENST00000399410;ENST00000574761;ENST00000575422;ENST00000572053;ENST00000574224;ENST00000399408","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005215(transporter activity);GO:0055085(transmembrane transport);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0016787(hydrolase activity);GO:0005886(plasma membrane);GO:0042626(ATPase activity, coupled to transmembrane movement of substances);GO:0016887(ATPase activity);GO:0005887(integral component of plasma membrane);GO:0035461(vitamin transmembrane transport);GO:0070062(extracellular exosome);GO:0009235(cobalamin metabolic process);GO:0008559(xenobiotic-transporting ATPase activity);GO:0043225(ATPase-coupled anion transmembrane transporter activity);GO:0006855(drug transmembrane transport);GO:0042908(xenobiotic transport);GO:0099133(ATP hydrolysis coupled anion transmembrane transport);GO:0016323(basolateral plasma membrane);GO:0042493(response to drug);GO:0006691(leukotriene metabolic process);GO:0015420(cobalamin-transporting ATPase activity);GO:0015431(glutathione S-conjugate-exporting ATPase activity);GO:0034634(glutathione transmembrane transporter activity);GO:0015889(cobalamin transport);GO:0034775(glutathione transmembrane transport);GO:0034775(glutathione transmembrane transport)","02010(ABC transporters);04071(Sphingolipid signaling pathway);04977(Vitamin digestion and absorption);05206(MicroRNAs in cancer);01523(Antifolate resistance);01523(Antifolate resistance)","K05665","NA","ATP binding cassette subfamily C member 1 [Source:HGNC Symbol;Acc:HGNC:51]",{"v":5.94252040541254,"d":"5.94"},{"v":1.70327032211221,"d":"1.70"},{"v":3.48888859757932,"d":"3.49"},{"v":1.80276753210214,"d":"1.80"},{"v":0.0220868719129121,"d":"0.02"},{"v":0.382257590945824,"d":"0.38"},"up","yes"]
["MSTRG.10450","TMEM184B","ENST00000361906;ENST00000633438;ENST00000488844;ENST00000474416;ENST00000464059;ENST00000457534;ENST00000633056;ENST00000466117;ENST00000436674","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005215(transporter activity);GO:0006810(transport);GO:0006810(transport)","NA","NA","NA","transmembrane protein 184B [Source:HGNC Symbol;Acc:HGNC:1310]",{"v":5.13687764915254,"d":"5.14"},{"v":1.46614298573446,"d":"1.47"},{"v":3.50366758163034,"d":"3.50"},{"v":1.80886590248383,"d":"1.81"},{"v":0.0221485513722259,"d":"0.02"},{"v":0.382754653401278,"d":"0.38"},"up","yes"]
["MSTRG.13948","CICP14","ENST00000629111","NA","NA","NA","NA","capicua transcriptional repressor pseudogene 14 [Source:HGNC Symbol;Acc:HGNC:38542]",{"v":2.373847,"d":"2.37"},{"v":0.661641,"d":"0.66"},{"v":3.58781726041766,"d":"3.59"},{"v":1.84310641082488,"d":"1.84"},{"v":0.0222039965988086,"d":"0.02"},{"v":0.383142663450171,"d":"0.38"},"up","yes"]
["MSTRG.10109","BCL2L13","ENST00000418951;ENST00000317582;ENST00000611738;ENST00000485631;ENST00000337612;ENST00000399781;ENST00000538149;ENST00000464649;ENST00000479296;ENST00000543133;ENST00000355028;ENST00000498133;ENST00000618481;ENST00000493680;ENST00000399777;ENST00000399782","GO:0005634(nucleus);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0042981(regulation of apoptotic process);GO:0005739(mitochondrion);GO:0005515(protein binding);GO:0006915(apoptotic process);GO:0031966(mitochondrial membrane);GO:0008656(cysteine-type endopeptidase activator activity involved in apoptotic process);GO:0006919(activation of cysteine-type endopeptidase activity involved in apoptotic process);GO:0006919(activation of cysteine-type endopeptidase activity involved in apoptotic process)","04137(Mitophagy - animal);05134(Legionellosis);05134(Legionellosis)","K15485","NA","BCL2 like 13 [Source:HGNC Symbol;Acc:HGNC:17164]",{"v":1.49307610636909,"d":"1.49"},{"v":3.60073003197598,"d":"3.60"},{"v":0.414659275510786,"d":"0.41"},{"v":-1.27000173055562,"d":"-1.27"},{"v":0.0223343709079779,"d":"0.02"},{"v":0.384810446785839,"d":"0.38"},"down","yes"]
["MSTRG.4500","SUSD6","ENST00000342745;MSTRG.4500.3;ENST00000553497;ENST00000556993","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005515(protein binding);GO:0006974(cellular response to DNA damage stimulus);GO:0003674(molecular_function);GO:0005575(cellular_component);GO:0008219(cell death);GO:0008219(cell death)","NA","NA","NA","sushi domain containing 6 [Source:HGNC Symbol;Acc:HGNC:19956]",{"v":7.5631694774575,"d":"7.56"},{"v":2.17062897900961,"d":"2.17"},{"v":3.4843216185699,"d":"3.48"},{"v":1.80087779732962,"d":"1.80"},{"v":0.0223683261158133,"d":"0.02"},{"v":0.384810446785839,"d":"0.38"},"up","yes"]
["ENSG00000060749","QSER1","ENST00000399302;ENST00000528034;ENST00000527788;ENST00000528155;ENST00000524678","NA","NA","NA","NA","glutamine and serine rich 1 [Source:HGNC Symbol;Acc:HGNC:26154]",{"v":1.56716550536206,"d":"1.57"},{"v":0.444950472905002,"d":"0.44"},{"v":3.52211223674023,"d":"3.52"},{"v":1.81644088327717,"d":"1.82"},{"v":0.0224182722347304,"d":"0.02"},{"v":0.384810446785839,"d":"0.38"},"up","yes"]
["MSTRG.12193","GLRX","ENST00000237858;ENST00000507412;ENST00000379979;ENST00000507605;ENST00000505427;ENST00000512469","GO:0005737(cytoplasm);GO:0016740(transferase activity);GO:0055114(oxidation-reduction process);GO:0005829(cytosol);GO:0045454(cell redox homeostasis);GO:0009055(electron carrier activity);GO:0015035(protein disulfide oxidoreductase activity);GO:0070062(extracellular exosome);GO:0047485(protein N-terminus binding);GO:0015949(nucleobase-containing small molecule interconversion);GO:2000651(positive regulation of sodium ion transmembrane transporter activity);GO:0015038(glutathione disulfide oxidoreductase activity);GO:0097573(glutathione oxidoreductase activity);GO:0045838(positive regulation of membrane potential);GO:0080058(protein deglutathionylation);GO:0005634(nucleus);GO:0005739(mitochondrion);GO:0005739(mitochondrion)","NA","NA","NA","glutaredoxin [Source:HGNC Symbol;Acc:HGNC:4330]",{"v":6.6499074302397,"d":"6.65"},{"v":15.8952020236632,"d":"15.90"},{"v":0.418359415648821,"d":"0.42"},{"v":-1.25718518996133,"d":"-1.26"},{"v":0.0224388029165938,"d":"0.02"},{"v":0.384810446785839,"d":"0.38"},"down","yes"]
["ENSG00000183337","BCOR","ENST00000397354;ENST00000378463;ENST00000490976;ENST00000342274;ENST00000615339;ENST00000442018;ENST00000378444;ENST00000406200;ENST00000378455","GO:0005634(nucleus);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0016569(covalent chromatin modification);GO:0005515(protein binding);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0003714(transcription corepressor activity);GO:0007507(heart development);GO:0008134(transcription factor binding);GO:0004842(ubiquitin-protein transferase activity);GO:0044212(transcription regulatory region DNA binding);GO:0045892(negative regulation of transcription, DNA-templated);GO:0031519(PcG protein complex);GO:0060021(palate development);GO:0042826(histone deacetylase binding);GO:0031072(heat shock protein binding);GO:0051572(negative regulation of histone H3-K4 methylation);GO:0035518(histone H2A monoubiquitination);GO:0030502(negative regulation of bone mineralization);GO:0042476(odontogenesis);GO:0000415(negative regulation of histone H3-K36 methylation);GO:0065001(specification of axis polarity);GO:0070171(negative regulation of tooth mineralization);GO:0000977(RNA polymerase II regulatory region sequence-specific DNA binding);GO:0000977(RNA polymerase II regulatory region sequence-specific DNA binding)","NA","NA","NA","BCL6 corepressor [Source:HGNC Symbol;Acc:HGNC:20893]",{"v":4.40364315133427,"d":"4.40"},{"v":1.26268505536049,"d":"1.26"},{"v":3.48752298337534,"d":"3.49"},{"v":1.80220272458121,"d":"1.80"},{"v":0.022482184786134,"d":"0.02"},{"v":0.384810446785839,"d":"0.38"},"up","yes"]
["ENSG00000104918","RETN","ENST00000221515;ENST00000629642","GO:0005576(extracellular region);GO:0005179(hormone activity);GO:0005615(extracellular space);GO:0008150(biological_process);GO:0070062(extracellular exosome);GO:0043312(neutrophil degranulation);GO:0035580(specific granule lumen);GO:0035578(azurophil granule lumen);GO:0007568(aging);GO:0009612(response to mechanical stimulus);GO:0010714(positive regulation of collagen metabolic process);GO:0014911(positive regulation of smooth muscle cell migration);GO:0032868(response to insulin);GO:0045444(fat cell differentiation);GO:0048661(positive regulation of smooth muscle cell proliferation);GO:0050806(positive regulation of synaptic transmission);GO:2000252(negative regulation of feeding behavior);GO:2000872(positive regulation of progesterone secretion);GO:0005634(nucleus);GO:0005634(nucleus)","NA","NA","NA","resistin [Source:HGNC Symbol;Acc:HGNC:20389]",{"v":1.74961969230769,"d":"1.75"},{"v":4.459184,"d":"4.46"},{"v":0.39236319746117,"d":"0.39"},{"v":-1.3497383676275,"d":"-1.35"},{"v":0.0224994655444403,"d":"0.02"},{"v":0.384810446785839,"d":"0.38"},"down","yes"]
["MSTRG.5357","RPL9P9","ENST00000466501;ENST00000418824","NA","NA","NA","NA","ribosomal protein L9 pseudogene 9 [Source:HGNC Symbol;Acc:HGNC:17251]",{"v":61.4656713933054,"d":"61.47"},{"v":146.70720960251,"d":"146.71"},{"v":0.418968308100475,"d":"0.42"},{"v":-1.25508697620258,"d":"-1.26"},{"v":0.0226001369907553,"d":"0.02"},{"v":0.385072660565956,"d":"0.39"},"down","yes"]
["MSTRG.5573","MMP25-AS1","MSTRG.5573.1;ENST00000573130;ENST00000570949;ENST00000572427;ENST00000573953;ENST00000572574;ENST00000572222","NA","NA","NA","NA","MMP25 antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:51372]",{"v":5.3606528309743,"d":"5.36"},{"v":1.53883222577985,"d":"1.54"},{"v":3.48358498162958,"d":"3.48"},{"v":1.80057275809024,"d":"1.80"},{"v":0.022616731951298,"d":"0.02"},{"v":0.385072660565956,"d":"0.39"},"up","yes"]
["ENSG00000149534","MS4A2","ENST00000278888;ENST00000524868;ENST00000617306;ENST00000440896","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005887(integral component of plasma membrane);GO:0006955(immune response);GO:0006954(inflammatory response);GO:0038095(Fc-epsilon receptor signaling pathway);GO:0005886(plasma membrane);GO:0032998(Fc-epsilon receptor I complex);GO:0019863(IgE binding);GO:0007165(signal transduction);GO:0007166(cell surface receptor signaling pathway);GO:0009897(external side of plasma membrane);GO:0009897(external side of plasma membrane)","04072(Phospholipase D signaling pathway);04071(Sphingolipid signaling pathway);04664(Fc epsilon RI signaling pathway);05310(Asthma);05310(Asthma)","K08090","NA","membrane spanning 4-domains A2 [Source:HGNC Symbol;Acc:HGNC:7316]",{"v":0.27433581877386,"d":"0.27"},{"v":0.68417516258702,"d":"0.68"},{"v":0.400973074989356,"d":"0.40"},{"v":-1.31842273073458,"d":"-1.32"},{"v":0.0226385726524517,"d":"0.02"},{"v":0.385072660565956,"d":"0.39"},"down","yes"]
["MSTRG.13058","ZNF318;CRIP3","ENST00000361428;ENST00000485819;ENST00000605935;ENST00000451294;ENST00000487744;ENST00000416431;ENST00000274990;ENST00000372569;ENST00000477866;ENST00000606599;ENST00000607252","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0051321(meiotic cell cycle);GO:0005737(cytoplasm);GO:0051321(meiotic cell cycle)","NA","NA","NA","zinc finger protein 318 [Source:HGNC Symbol;Acc:HGNC:13578];cysteine rich protein 3 [Source:HGNC Symbol;Acc:HGNC:17751]",{"v":3.41052917180238,"d":"3.41"},{"v":0.979480530125667,"d":"0.98"},{"v":3.48197750430507,"d":"3.48"},{"v":1.79990688233067,"d":"1.80"},{"v":0.0226474319440754,"d":"0.02"},{"v":0.385072660565956,"d":"0.39"},"up","yes"]
["MSTRG.12844","HCP5","MSTRG.12844.1","NA","NA","NA","NA",null,{"v":8.719362,"d":"8.72"},{"v":2.511325,"d":"2.51"},{"v":3.47201656496073,"d":"3.47"},{"v":1.79577383088426,"d":"1.80"},{"v":0.0227047838946393,"d":"0.02"},{"v":0.385483414281355,"d":"0.39"},"up","yes"]
["ENSG00000129315","CCNT1","ENST00000261900;ENST00000618666;ENST00000417344;ENST00000640148;ENST00000550457;ENST00000551989","GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0051301(cell division);GO:0005515(protein binding);GO:0007049(cell cycle);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0016032(viral process);GO:0004674(protein serine/threonine kinase activity);GO:0006366(transcription from RNA polymerase II promoter);GO:0006368(transcription elongation from RNA polymerase II promoter);GO:0050434(positive regulation of viral transcription);GO:1900364(negative regulation of mRNA polyadenylation);GO:0003677(DNA binding);GO:0042795(snRNA transcription from RNA polymerase II promoter);GO:0006468(protein phosphorylation);GO:0008134(transcription factor binding);GO:0003682(chromatin binding);GO:0016538(cyclin-dependent protein serine/threonine kinase regulator activity);GO:0017069(snRNA binding);GO:0019901(protein kinase binding);GO:0044212(transcription regulatory region DNA binding);GO:0070063(RNA polymerase binding);GO:0097322(7SK snRNA binding);GO:0000079(regulation of cyclin-dependent protein serine/threonine kinase activity);GO:0043923(positive regulation by host of viral transcription);GO:0045737(positive regulation of cyclin-dependent protein serine/threonine kinase activity);GO:1901409(positive regulation of phosphorylation of RNA polymerase II C-terminal domain);GO:0008024(cyclin/CDK positive transcription elongation factor complex);GO:0008024(cyclin/CDK positive transcription elongation factor complex)","05202(Transcriptional misregulation in cancers);05202(Transcriptional misregulation in cancers)","K15188","NA","cyclin T1 [Source:HGNC Symbol;Acc:HGNC:1599]",{"v":1.34847988890394,"d":"1.35"},{"v":3.22632676249831,"d":"3.23"},{"v":0.41796134990981,"d":"0.42"},{"v":-1.25855855658007,"d":"-1.26"},{"v":0.0229487207591512,"d":"0.02"},{"v":0.388987877929892,"d":"0.39"},"down","yes"]
["ENSG00000102908","NFAT5","ENST00000567239;ENST00000354436;ENST00000426654;ENST00000393742;ENST00000565301;ENST00000567990;ENST00000349945;ENST00000568832;ENST00000566899;ENST00000562429;ENST00000627621","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0006366(transcription from RNA polymerase II promoter);GO:0005515(protein binding);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0007165(signal transduction);GO:0001077(transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0007588(excretion);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0001816(cytokine production);GO:0006970(response to osmotic stress);GO:0010628(positive regulation of gene expression);GO:0070884(regulation of calcineurin-NFAT signaling cascade);GO:0070884(regulation of calcineurin-NFAT signaling cascade)","NA","NA","NA","nuclear factor of activated T-cells 5 [Source:HGNC Symbol;Acc:HGNC:7774]",{"v":1.99062349801841,"d":"1.99"},{"v":0.572092391012743,"d":"0.57"},{"v":3.47954898420257,"d":"3.48"},{"v":1.79890031744681,"d":"1.80"},{"v":0.0229888486164427,"d":"0.02"},{"v":0.388987877929892,"d":"0.39"},"up","yes"]
["MSTRG.12765","PRR3","ENST00000491173;ENST00000498336;ENST00000376557;ENST00000376560;ENST00000481741;ENST00000470703","GO:0003723(RNA binding);GO:0046872(metal ion binding);GO:0005515(protein binding);GO:0005515(protein binding)","NA","NA","NA","proline rich 3 [Source:HGNC Symbol;Acc:HGNC:21149]",{"v":0.478448540527914,"d":"0.48"},{"v":1.17818995772016,"d":"1.18"},{"v":0.406087776756924,"d":"0.41"},{"v":-1.30013649209586,"d":"-1.30"},{"v":0.0230281469364859,"d":"0.02"},{"v":0.388987877929892,"d":"0.39"},"down","yes"]
["ENSG00000128731","HERC2","ENST00000261609;ENST00000563670;ENST00000564519;ENST00000569335;ENST00000564383;ENST00000562136;ENST00000566635;ENST00000567869;ENST00000568206","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0016740(transferase activity);GO:0016567(protein ubiquitination);GO:0004842(ubiquitin-protein transferase activity);GO:0043547(positive regulation of GTPase activity);GO:0005856(cytoskeleton);GO:0006281(DNA repair);GO:0006974(cellular response to DNA damage stimulus);GO:0006886(intracellular protein transport);GO:0005085(guanyl-nucleotide exchange factor activity);GO:0061630(ubiquitin protein ligase activity);GO:0043161(proteasome-mediated ubiquitin-dependent protein catabolic process);GO:0005515(protein binding);GO:0005654(nucleoplasm);GO:0005814(centriole);GO:0031625(ubiquitin protein ligase binding);GO:0006303(double-strand break repair via nonhomologous end joining);GO:0032183(SUMO binding);GO:0007283(spermatogenesis);GO:0005743(mitochondrial inner membrane);GO:0005743(mitochondrial inner membrane)","04120(Ubiquitin mediated proteolysis);04120(Ubiquitin mediated proteolysis)","K10595","EC:2.3.2.26","HECT and RLD domain containing E3 ubiquitin protein ligase 2 [Source:HGNC Symbol;Acc:HGNC:4868]",{"v":1.83102568817097,"d":"1.83"},{"v":0.52788882174065,"d":"0.53"},{"v":3.4685820437216,"d":"3.47"},{"v":1.79434600961312,"d":"1.79"},{"v":0.0230541797391264,"d":"0.02"},{"v":0.388987877929892,"d":"0.39"},"up","yes"]
["ENSG00000188747","NOXA1","ENST00000341349","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005886(plasma membrane);GO:0043085(positive regulation of catalytic activity);GO:0005515(protein binding);GO:0006801(superoxide metabolic process);GO:0043020(NADPH oxidase complex);GO:0005829(cytosol);GO:0017124(SH3 domain binding);GO:0019899(enzyme binding);GO:0048365(Rac GTPase binding);GO:0016176(superoxide-generating NADPH oxidase activator activity);GO:0010310(regulation of hydrogen peroxide metabolic process);GO:0060263(regulation of respiratory burst)","NA","NA","NA","NADPH oxidase activator 1 [Source:HGNC Symbol;Acc:HGNC:10668]",{"v":0.488454,"d":"0.49"},{"v":1.237792,"d":"1.24"},{"v":0.394617189317753,"d":"0.39"},{"v":-1.34147429441799,"d":"-1.34"},{"v":0.023078674579669,"d":"0.02"},{"v":0.388987877929892,"d":"0.39"},"down","yes"]
["ENSG00000076356","PLXNA2","ENST00000367033;ENST00000480053;ENST00000460870;ENST00000483048","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0007165(signal transduction);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0017154(semaphorin receptor activity);GO:0071526(semaphorin-plexin signaling pathway);GO:0005887(integral component of plasma membrane);GO:0030334(regulation of cell migration);GO:0002116(semaphorin receptor complex);GO:0001756(somitogenesis);GO:0007166(cell surface receptor signaling pathway);GO:0021785(branchiomotor neuron axon guidance);GO:0021915(neural tube development);GO:0021935(cerebellar granule cell precursor tangential migration);GO:0048841(regulation of axon extension involved in axon guidance);GO:0051642(centrosome localization);GO:0060037(pharyngeal system development);GO:0060174(limb bud formation);GO:0060174(limb bud formation)","04360(Axon guidance);04360(Axon guidance)","K06820","NA","plexin A2 [Source:HGNC Symbol;Acc:HGNC:9100]",{"v":0.536358819534141,"d":"0.54"},{"v":0.1495378447863,"d":"0.15"},{"v":3.58677644646166,"d":"3.59"},{"v":1.84268782903344,"d":"1.84"},{"v":0.0231772712044284,"d":"0.02"},{"v":0.389141616028926,"d":"0.39"},"up","yes"]
["MSTRG.5781","NFATC2IP","ENST00000320805;ENST00000568998;ENST00000564978;ENST00000568148;ENST00000565752","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016925(protein sumoylation);GO:0031386(protein tag);GO:0001816(cytokine production);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0045944(positive regulation of transcription from RNA polymerase II promoter)","NA","NA","NA","nuclear factor of activated T-cells 2 interacting protein [Source:HGNC Symbol;Acc:HGNC:25906]",{"v":5.35487727344022,"d":"5.35"},{"v":1.54335563698153,"d":"1.54"},{"v":3.46963275678521,"d":"3.47"},{"v":1.79478296885449,"d":"1.79"},{"v":0.0231843735974432,"d":"0.02"},{"v":0.389141616028926,"d":"0.39"},"up","yes"]
["MSTRG.1706","WDFY4","ENST00000325239;ENST00000490507;ENST00000374161;ENST00000465910;ENST00000360890","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016021(integral component of membrane)","NA","NA","NA","WDFY family member 4 [Source:HGNC Symbol;Acc:HGNC:29323]",{"v":6.68942157493786,"d":"6.69"},{"v":1.93618820309987,"d":"1.94"},{"v":3.45494387592486,"d":"3.45"},{"v":1.78866227484435,"d":"1.79"},{"v":0.023188323283563,"d":"0.02"},{"v":0.389141616028926,"d":"0.39"},"up","yes"]
["MSTRG.13350","LATS1","ENST00000543571;ENST00000392273;ENST00000441107;ENST00000542747","GO:0090090(negative regulation of canonical Wnt signaling pathway);GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0035329(hippo signaling);GO:0051301(cell division);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0007049(cell cycle);GO:0000287(magnesium ion binding);GO:0000922(spindle pole);GO:0005815(microtubule organizing center);GO:0000278(mitotic cell cycle);GO:0005829(cytosol);GO:0019901(protein kinase binding);GO:0030331(estrogen receptor binding);GO:0009755(hormone-mediated signaling pathway);GO:0033138(positive regulation of peptidyl-serine phosphorylation);GO:0045736(negative regulation of cyclin-dependent protein serine/threonine kinase activity);GO:0060644(mammary gland epithelial cell differentiation);GO:0000086(G2/M transition of mitotic cell cycle);GO:0030833(regulation of actin filament polymerization);GO:0033146(regulation of intracellular estrogen receptor signaling pathway);GO:0000082(G1/S transition of mitotic cell cycle);GO:0000819(sister chromatid segregation);GO:0001827(inner cell mass cell fate commitment);GO:0001828(inner cell mass cellular morphogenesis);GO:0030216(keratinocyte differentiation);GO:0034613(cellular protein localization);GO:0043065(positive regulation of apoptotic process);GO:0043254(regulation of protein complex assembly);GO:0046620(regulation of organ growth);GO:0051220(cytoplasmic sequestering of protein);GO:2000058(regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process);GO:0005622(intracellular);GO:0005622(intracellular)","04390(Hippo signaling pathway);04392(Hippo signaling pathway - multiple species);04392(Hippo signaling pathway - multiple species)","K08791","EC:2.7.11.1","large tumor suppressor kinase 1 [Source:HGNC Symbol;Acc:HGNC:6514]",{"v":4.32627538088627,"d":"4.33"},{"v":1.24917165798912,"d":"1.25"},{"v":3.46331535239166,"d":"3.46"},{"v":1.79215375820158,"d":"1.79"},{"v":0.0232525748740321,"d":"0.02"},{"v":0.389350020396795,"d":"0.39"},"up","yes"]
["MSTRG.154","UBIAD1","ENST00000376810;ENST00000376804;ENST00000486588;ENST00000483738","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016740(transferase activity);GO:0005794(Golgi apparatus);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005739(mitochondrion);GO:0005515(protein binding);GO:0000139(Golgi membrane);GO:0098869(cellular oxidant detoxification);GO:0031966(mitochondrial membrane);GO:0016765(transferase activity, transferring alkyl or aryl (other than methyl) groups);GO:0006744(ubiquinone biosynthetic process);GO:0004659(prenyltransferase activity);GO:0030173(integral component of Golgi membrane);GO:0016209(antioxidant activity);GO:0042373(vitamin K metabolic process);GO:0009234(menaquinone biosynthetic process);GO:0032194(ubiquinone biosynthetic process via 3,4-dihydroxy-5-polyprenylbenzoate);GO:0042371(vitamin K biosynthetic process);GO:0042371(vitamin K biosynthetic process)","NA","NA","NA","UbiA prenyltransferase domain containing 1 [Source:HGNC Symbol;Acc:HGNC:30791]",{"v":1.05151048307753,"d":"1.05"},{"v":2.52039525718221,"d":"2.52"},{"v":0.417200627592481,"d":"0.42"},{"v":-1.26118676679028,"d":"-1.26"},{"v":0.0233010214178586,"d":"0.02"},{"v":0.389350020396795,"d":"0.39"},"down","yes"]
["MSTRG.2844","C11orf57","ENST00000393047;ENST00000531378;ENST00000280352;ENST00000530104;ENST00000526879;ENST00000420986;ENST00000525785;ENST00000524989;ENST00000532163","GO:0005515(protein binding);GO:0005515(protein binding)","NA","NA","NA","chromosome 11 open reading frame 57 [Source:HGNC Symbol;Acc:HGNC:25569]",{"v":2.63229738436143,"d":"2.63"},{"v":0.748378693831451,"d":"0.75"},{"v":3.51733341162472,"d":"3.52"},{"v":1.81448209598087,"d":"1.81"},{"v":0.0233013230152219,"d":"0.02"},{"v":0.389350020396795,"d":"0.39"},"up","yes"]
["ENSG00000132326","PER2","ENST00000254657","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0006631(fatty acid metabolic process);GO:0005515(protein binding);GO:0048511(rhythmic process);GO:0048471(perinuclear region of cytoplasm);GO:0003713(transcription coactivator activity);GO:0005730(nucleolus);GO:0006094(gluconeogenesis);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0005978(glycogen biosynthetic process);GO:0045892(negative regulation of transcription, DNA-templated);GO:0000976(transcription regulatory region sequence-specific DNA binding);GO:0007623(circadian rhythm);GO:0032922(circadian regulation of gene expression);GO:0050767(regulation of neurogenesis);GO:0050796(regulation of insulin secretion);GO:0051726(regulation of cell cycle);GO:0070345(negative regulation of fat cell proliferation);GO:0031397(negative regulation of protein ubiquitination);GO:0000989(transcription factor activity, transcription factor binding);GO:0002931(response to ischemia);GO:0019229(regulation of vasoconstriction);GO:0019249(lactate biosynthetic process);GO:0042752(regulation of circadian rhythm);GO:0042754(negative regulation of circadian rhythm);GO:0050872(white fat cell differentiation);GO:0051946(regulation of glutamate uptake involved in transmission of nerve impulse);GO:0070932(histone H3 deacetylation);GO:0097167(circadian regulation of translation);GO:2000678(negative regulation of transcription regulatory region DNA binding)","04710(Circadian rhythm);04713(Circadian entrainment);05202(Transcriptional misregulation in cancers);05221(Acute myeloid leukemia);05168(Herpes simplex infection)","K02633","NA","period circadian clock 2 [Source:HGNC Symbol;Acc:HGNC:8846]",{"v":1.60451234041006,"d":"1.60"},{"v":0.457651397411662,"d":"0.46"},{"v":3.50597059133807,"d":"3.51"},{"v":1.80981389458329,"d":"1.81"},{"v":0.0233989998753193,"d":"0.02"},{"v":0.390420381540348,"d":"0.39"},"up","yes"]
["MSTRG.6848","RPL27","ENST00000589913;ENST00000588830;ENST00000253788;ENST00000587478;ENST00000589037;ENST00000593262;ENST00000590864;ENST00000586277","GO:0003723(RNA binding);GO:0005634(nucleus);GO:0016020(membrane);GO:0006412(translation);GO:0030529(intracellular ribonucleoprotein complex);GO:0005622(intracellular);GO:0003735(structural constituent of ribosome);GO:0005840(ribosome);GO:0005925(focal adhesion);GO:0006364(rRNA processing);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0031012(extracellular matrix);GO:0006413(translational initiation);GO:0000184(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay);GO:0019083(viral transcription);GO:0006614(SRP-dependent cotranslational protein targeting to membrane);GO:0022625(cytosolic large ribosomal subunit);GO:0022625(cytosolic large ribosomal subunit)","03010(Ribosome);03010(Ribosome)","K02901","NA","ribosomal protein L27 [Source:HGNC Symbol;Acc:HGNC:10328]",{"v":127.081164119941,"d":"127.08"},{"v":300.777547035044,"d":"300.78"},{"v":0.422508812152573,"d":"0.42"},{"v":-1.2429466632766,"d":"-1.24"},{"v":0.0235161149892578,"d":"0.02"},{"v":0.391811539986013,"d":"0.39"},"down","yes"]
["MSTRG.12917","GPSM3;NOTCH4","ENST00000375040;ENST00000487761;ENST00000619085;ENST00000472768;ENST00000491215;MSTRG.12917.7;ENST00000375023;ENST00000375043;MSTRG.12917.1","GO:0030695(GTPase regulator activity);GO:0050790(regulation of catalytic activity);GO:0005092(GDP-dissociation inhibitor activity);GO:1900015(regulation of cytokine production involved in inflammatory response);GO:0005737(cytoplasm);GO:0005515(protein binding);GO:0002690(positive regulation of leukocyte chemotaxis);GO:0050729(positive regulation of inflammatory response);GO:1900017(positive regulation of cytokine production involved in inflammatory response);GO:0005886(plasma membrane);GO:0003674(molecular_function);GO:0008150(biological_process);GO:0005575(cellular_component);GO:0006955(immune response);GO:0005634(nucleus);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0005509(calcium ion binding);GO:0007275(multicellular organism development);GO:0030154(cell differentiation);GO:0007219(Notch signaling pathway);GO:0004872(receptor activity);GO:0045893(positive regulation of transcription, DNA-templated);GO:0005576(extracellular region);GO:0005887(integral component of plasma membrane);GO:0050793(regulation of developmental process);GO:0005789(endoplasmic reticulum membrane);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0009986(cell surface);GO:0046982(protein heterodimerization activity);GO:0006367(transcription initiation from RNA polymerase II promoter);GO:0000139(Golgi membrane);GO:0009790(embryo development);GO:0001709(cell fate determination);GO:0007220(Notch receptor processing);GO:0030097(hemopoiesis);GO:0045596(negative regulation of cell differentiation);GO:0001569(branching involved in blood vessel morphogenesis);GO:0030879(mammary gland development);GO:0001763(morphogenesis of a branching structure);GO:0007221(positive regulation of transcription of Notch receptor target);GO:0045602(negative regulation of endothelial cell differentiation);GO:0001886(endothelial cell morphogenesis);GO:0045446(endothelial cell differentiation);GO:0006955(immune response)","04330(Notch signaling pathway);04919(Thyroid hormone signaling pathway);05200(Pathways in cancer);05206(MicroRNAs in cancer);05224(Breast cancer);05165(Human papillomavirus infection);01522(Endocrine resistance);01522(Endocrine resistance)","K20996","NA","G protein signaling modulator 3 [Source:HGNC Symbol;Acc:HGNC:13945];notch 4 [Source:HGNC Symbol;Acc:HGNC:7884]",{"v":5.76788467719542,"d":"5.77"},{"v":13.6562103340854,"d":"13.66"},{"v":0.422363491487751,"d":"0.42"},{"v":-1.24344295935268,"d":"-1.24"},{"v":0.0235603783668582,"d":"0.02"},{"v":0.391986638931696,"d":"0.39"},"down","yes"]
["MSTRG.2596","KDM2A","ENST00000529006;ENST00000530342;ENST00000534486;ENST00000527157;ENST00000528380;ENST00000524657;ENST00000398645;ENST00000529124;ENST00000525041;ENST00000308783;ENST00000532436;ENST00000526258;ENST00000525379;ENST00000517637;ENST00000531696","GO:0005634(nucleus);GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0016569(covalent chromatin modification);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0051213(dioxygenase activity);GO:0005654(nucleoplasm);GO:0006303(double-strand break repair via nonhomologous end joining);GO:0032452(histone demethylase activity);GO:0051864(histone demethylase activity (H3-K36 specific));GO:0070544(histone H3-K36 demethylation);GO:0008168(methyltransferase activity);GO:0032259(methylation);GO:0032259(methylation)","NA","NA","NA","lysine demethylase 2A [Source:HGNC Symbol;Acc:HGNC:13606]",{"v":15.2408183273603,"d":"15.24"},{"v":4.43124490211946,"d":"4.43"},{"v":3.4393987838656,"d":"3.44"},{"v":1.78215640000277,"d":"1.78"},{"v":0.0236575457752694,"d":"0.02"},{"v":0.39304017036939,"d":"0.39"},"up","yes"]
["MSTRG.10673","IQSEC1","ENST00000613206;MSTRG.10673.2;MSTRG.10673.7;ENST00000618604;ENST00000273221;ENST00000473088","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0043231(intracellular membrane-bounded organelle);GO:0005730(nucleolus);GO:0005515(protein binding);GO:0005086(ARF guanyl-nucleotide exchange factor activity);GO:0032012(regulation of ARF protein signal transduction);GO:0043547(positive regulation of GTPase activity);GO:0005085(guanyl-nucleotide exchange factor activity);GO:0008289(lipid binding);GO:0030036(actin cytoskeleton organization);GO:0030036(actin cytoskeleton organization)","04144(Endocytosis);04144(Endocytosis)","K12495","NA","IQ motif and Sec7 domain 1 [Source:HGNC Symbol;Acc:HGNC:29112]",{"v":25.7238448096555,"d":"25.72"},{"v":7.49205707293467,"d":"7.49"},{"v":3.43348222780948,"d":"3.43"},{"v":1.77967249604013,"d":"1.78"},{"v":0.0237508413290838,"d":"0.02"},{"v":0.393929131578325,"d":"0.39"},"up","yes"]
["ENSG00000242687","AC004893.2","ENST00000468960;ENST00000360902;ENST00000482799","NA","NA","NA","NA",null,{"v":0.898854480686695,"d":"0.90"},{"v":0.249186745350501,"d":"0.25"},{"v":3.60715205546902,"d":"3.61"},{"v":1.8508602396066,"d":"1.85"},{"v":0.0238476753956158,"d":"0.02"},{"v":0.393929131578325,"d":"0.39"},"up","yes"]
["MSTRG.11655","CXCL8","ENST00000307407;ENST00000483500;ENST00000401931","GO:0005622(intracellular);GO:0071222(cellular response to lipopolysaccharide);GO:0005576(extracellular region);GO:0005515(protein binding);GO:0006955(immune response);GO:0006935(chemotaxis);GO:0005125(cytokine activity);GO:0005615(extracellular space);GO:0008009(chemokine activity);GO:0006952(defense response);GO:0005153(interleukin-8 receptor binding);GO:0006954(inflammatory response);GO:0030593(neutrophil chemotaxis);GO:0042119(neutrophil activation);GO:0070098(chemokine-mediated signaling pathway);GO:0007050(cell cycle arrest);GO:0071347(cellular response to interleukin-1);GO:0071356(cellular response to tumor necrosis factor);GO:0007186(G-protein coupled receptor signaling pathway);GO:0007165(signal transduction);GO:0006928(movement of cell or subcellular component);GO:0034976(response to endoplasmic reticulum stress);GO:0001525(angiogenesis);GO:0030155(regulation of cell adhesion);GO:0035556(intracellular signal transduction);GO:0090023(positive regulation of neutrophil chemotaxis);GO:0008285(negative regulation of cell proliferation);GO:0044344(cellular response to fibroblast growth factor stimulus);GO:0019722(calcium-mediated signaling);GO:0050930(induction of positive chemotaxis);GO:0045744(negative regulation of G-protein coupled receptor protein signaling pathway);GO:0031623(receptor internalization);GO:0048566(embryonic digestive tract development);GO:0045766(positive regulation of angiogenesis);GO:0036499(PERK-mediated unfolded protein response);GO:0002237(response to molecule of bacterial origin);GO:0045091(regulation of single stranded viral RNA replication via double stranded DNA intermediate);GO:2000535(regulation of entry of bacterium into host cell);GO:2000535(regulation of entry of bacterium into host cell)","04064(NF-kappa B signaling pathway);04072(Phospholipase D signaling pathway);04060(Cytokine-cytokine receptor interaction);04218(Cellular senescence);04620(Toll-like receptor signaling pathway);04621(NOD-like receptor signaling pathway);04622(RIG-I-like receptor signaling pathway);04657(IL-17 signaling pathway);04062(Chemokine signaling pathway);05200(Pathways in cancer);05202(Transcriptional misregulation in cancers);05219(Bladder cancer);05323(Rheumatoid arthritis);04932(Non-alcoholic fatty liver disease (NAFLD));04933(AGE-RAGE signaling pathway in diabetic complications);05120(Epithelial cell signaling in Helicobacter pylori infection);05132(Salmonella infection);05131(Shigellosis);05133(Pertussis);05134(Legionellosis);05164(Influenza A);05161(Hepatitis B);05160(Hepatitis C);05167(Kaposi's sarcoma-associated herpesvirus infection);05146(Amoebiasis);05144(Malaria);05142(Chagas disease (American trypanosomiasis));05142(Chagas disease (American trypanosomiasis))","K10030","NA","C-X-C motif chemokine ligand 8 [Source:HGNC Symbol;Acc:HGNC:6025]",{"v":33.2095756240106,"d":"33.21"},{"v":9.6589830646438,"d":"9.66"},{"v":3.43820621712989,"d":"3.44"},{"v":1.78165607754095,"d":"1.78"},{"v":0.0238537080981097,"d":"0.02"},{"v":0.393929131578325,"d":"0.39"},"up","yes"]
["MSTRG.9494","PDE6D","ENST00000287600;ENST00000409772;ENST00000486044;ENST00000428104;ENST00000477748","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005829(cytosol);GO:0007601(visual perception);GO:0005856(cytoskeleton);GO:0042995(cell projection);GO:0005515(protein binding);GO:0030659(cytoplasmic vesicle membrane);GO:0031410(cytoplasmic vesicle);GO:0004114(3',5'-cyclic-nucleotide phosphodiesterase activity);GO:0050896(response to stimulus);GO:0005929(cilium);GO:0034260(negative regulation of GTPase activity);GO:0017137(Rab GTPase binding);GO:0005095(GTPase inhibitor activity);GO:0005095(GTPase inhibitor activity)","00230(Purine metabolism);00230(Purine metabolism)","K13758","NA","phosphodiesterase 6D [Source:HGNC Symbol;Acc:HGNC:8788]",{"v":1.38239906842105,"d":"1.38"},{"v":3.32036236245614,"d":"3.32"},{"v":0.416339820030505,"d":"0.42"},{"v":-1.264166545986,"d":"-1.26"},{"v":0.0239340060185108,"d":"0.02"},{"v":0.393929131578325,"d":"0.39"},"down","yes"]
["MSTRG.1058","LAMTOR2","ENST00000368305;ENST00000368302;ENST00000489664;ENST00000368304;ENST00000463371;ENST00000487106","GO:0016020(membrane);GO:0005765(lysosomal membrane);GO:0043547(positive regulation of GTPase activity);GO:0005515(protein binding);GO:0005764(lysosome);GO:0005085(guanyl-nucleotide exchange factor activity);GO:0005886(plasma membrane);GO:0071230(cellular response to amino acid stimulus);GO:0005768(endosome);GO:0031902(late endosome membrane);GO:0070062(extracellular exosome);GO:0010008(endosome membrane);GO:0000165(MAPK cascade);GO:0005770(late endosome);GO:0043312(neutrophil degranulation);GO:0035579(specific granule membrane);GO:0070821(tertiary granule membrane);GO:0016049(cell growth);GO:0032008(positive regulation of TOR signaling);GO:0032947(protein complex scaffold);GO:0007050(cell cycle arrest);GO:0016241(regulation of macroautophagy);GO:0071986(Ragulator complex);GO:0034613(cellular protein localization);GO:0000186(activation of MAPKK activity);GO:0000186(activation of MAPKK activity)","04150(mTOR signaling pathway);04150(mTOR signaling pathway)","K20398","NA","late endosomal/lysosomal adaptor, MAPK and MTOR activator 2 [Source:HGNC Symbol;Acc:HGNC:29796]",{"v":5.41216981571627,"d":"5.41"},{"v":12.8846457239221,"d":"12.88"},{"v":0.420048011538869,"d":"0.42"},{"v":-1.25137385735233,"d":"-1.25"},{"v":0.0239630417914559,"d":"0.02"},{"v":0.393929131578325,"d":"0.39"},"down","yes"]
["MSTRG.12364","PAIP2","ENST00000510409;ENST00000265192;ENST00000507415;ENST00000510080;ENST00000511381;ENST00000394795","GO:0005737(cytoplasm);GO:0005515(protein binding);GO:0006417(regulation of translation);GO:0030371(translation repressor activity);GO:0045947(negative regulation of translational initiation);GO:0003729(mRNA binding);GO:0007283(spermatogenesis);GO:0007613(memory);GO:0017148(negative regulation of translation);GO:1900271(regulation of long-term synaptic potentiation);GO:1900271(regulation of long-term synaptic potentiation)","NA","NA","NA","poly(A) binding protein interacting protein 2 [Source:HGNC Symbol;Acc:HGNC:17970]",{"v":19.4887869468018,"d":"19.49"},{"v":46.0006176865105,"d":"46.00"},{"v":0.423663592511211,"d":"0.42"},{"v":-1.23900893871405,"d":"-1.24"},{"v":0.0239852581653185,"d":"0.02"},{"v":0.393929131578325,"d":"0.39"},"down","yes"]
["ENSG00000188807","TMEM201","ENST00000340305;ENST00000340381;ENST00000510900;ENST00000416541","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005856(cytoskeleton);GO:0000922(spindle pole);GO:0005637(nuclear inner membrane);GO:0005521(lamin binding);GO:0051015(actin filament binding);GO:0007097(nuclear migration);GO:0010761(fibroblast migration);GO:0031965(nuclear membrane);GO:0031965(nuclear membrane)","NA","NA","NA","transmembrane protein 201 [Source:HGNC Symbol;Acc:HGNC:33719]",{"v":0.527753377978754,"d":"0.53"},{"v":0.146090848406546,"d":"0.15"},{"v":3.61250128762416,"d":"3.61"},{"v":1.85299810184132,"d":"1.85"},{"v":0.0239974159296355,"d":"0.02"},{"v":0.393929131578325,"d":"0.39"},"up","yes"]
["MSTRG.813","RHOC;AL603832.3;PPM1J","ENST00000369642;ENST00000369637;ENST00000339083;ENST00000369632;ENST00000425265;ENST00000471038;ENST00000468093;ENST00000369636;ENST00000484280;ENST00000369638;ENST00000473074;ENST00000285735;ENST00000464951;ENST00000478447;ENST00000528831;ENST00000606954;ENST00000309276;ENST00000606505;ENST00000414971;ENST00000534717;ENST00000607158;ENST00000369633","GO:0016020(membrane);GO:0005525(GTP binding);GO:0007264(small GTPase mediated signal transduction);GO:0000166(nucleotide binding);GO:0003924(GTPase activity);GO:0005622(intracellular);GO:0005886(plasma membrane);GO:0044319(wound healing, spreading of cells);GO:1902766(skeletal muscle satellite cell migration);GO:0005515(protein binding);GO:0004871(signal transducer activity);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0051056(regulation of small GTPase mediated signal transduction);GO:0032154(cleavage furrow);GO:0032420(stereocilium);GO:0043123(positive regulation of I-kappaB kinase/NF-kappaB signaling);GO:0000910(cytokinesis);GO:0043297(apical junction assembly);GO:0032464(positive regulation of protein homooligomerization);GO:0060193(positive regulation of lipase activity);GO:0005634(nucleus);GO:0003824(catalytic activity);GO:0006470(protein dephosphorylation);GO:0004722(protein serine/threonine phosphatase activity);GO:0016787(hydrolase activity);GO:0004721(phosphoprotein phosphatase activity);GO:0005634(nucleus)","NA","NA","NA","ras homolog family member C [Source:HGNC Symbol;Acc:HGNC:669];protein phosphatase, Mg2+/Mn2+ dependent 1J [Source:HGNC Symbol;Acc:HGNC:20785]",{"v":2.52510580496102,"d":"2.53"},{"v":5.98943358086463,"d":"5.99"},{"v":0.421593422962125,"d":"0.42"},{"v":-1.24607573439691,"d":"-1.25"},{"v":0.0239998391401526,"d":"0.02"},{"v":0.393929131578325,"d":"0.39"},"down","yes"]
["MSTRG.3468","RBMS2","ENST00000262031;ENST00000639027;ENST00000542360;ENST00000552228;ENST00000552916","GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0005634(nucleus);GO:0006396(RNA processing);GO:0006396(RNA processing)","NA","NA","NA","RNA binding motif single stranded interacting protein 2 [Source:HGNC Symbol;Acc:HGNC:9909]",{"v":0.907532270208901,"d":"0.91"},{"v":0.257775283378747,"d":"0.26"},{"v":3.52063339166413,"d":"3.52"},{"v":1.81583500522862,"d":"1.82"},{"v":0.0240163459190092,"d":"0.02"},{"v":0.393929131578325,"d":"0.39"},"up","yes"]
["MSTRG.11326","GPR160;AC008040.2","ENST00000355897;ENST00000473675;ENST00000461049;ENST00000478364;ENST00000482813;ENST00000492492;ENST00000485735;ENST00000491740;ENST00000482710;ENST00000476668","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005886(plasma membrane);GO:0004871(signal transducer activity);GO:0007165(signal transduction);GO:0004930(G-protein coupled receptor activity);GO:0007186(G-protein coupled receptor signaling pathway);GO:0043235(receptor complex);GO:0043235(receptor complex)","NA","NA","NA","G protein-coupled receptor 160 [Source:HGNC Symbol;Acc:HGNC:23693]",{"v":3.05673581665591,"d":"3.06"},{"v":0.878446993544222,"d":"0.88"},{"v":3.47970434086531,"d":"3.48"},{"v":1.79896473018665,"d":"1.80"},{"v":0.0240607239038388,"d":"0.02"},{"v":0.394100404365697,"d":"0.39"},"up","yes"]
["ENSG00000003147","ICA1","ENST00000407906;ENST00000470696;ENST00000402384","GO:0006810(transport);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0043231(intracellular membrane-bounded organelle);GO:0005829(cytosol);GO:0005794(Golgi apparatus);GO:0019904(protein domain specific binding);GO:0005515(protein binding);GO:0000139(Golgi membrane);GO:0030054(cell junction);GO:0045202(synapse);GO:0031410(cytoplasmic vesicle);GO:0050796(regulation of insulin secretion);GO:0030667(secretory granule membrane);GO:0030672(synaptic vesicle membrane);GO:0003674(molecular_function);GO:0006836(neurotransmitter transport);GO:0030658(transport vesicle membrane);GO:0016021(integral component of membrane);GO:0016021(integral component of membrane)","04940(Type I diabetes mellitus);04940(Type I diabetes mellitus)","K19863","NA","islet cell autoantigen 1 [Source:HGNC Symbol;Acc:HGNC:5343]",{"v":0.1565633751789,"d":"0.16"},{"v":0.400152395829074,"d":"0.40"},{"v":0.391259372206224,"d":"0.39"},{"v":-1.3538027841878,"d":"-1.35"},{"v":0.0241189575270833,"d":"0.02"},{"v":0.394336224290762,"d":"0.39"},"down","yes"]
["MSTRG.14607","LY6E","ENST00000292494;ENST00000429120;ENST00000521699;ENST00000519611;ENST00000519546;ENST00000521003;ENST00000520531;ENST00000521182;ENST00000520466;ENST00000519615;ENST00000522024;ENST00000517503;ENST00000523847;ENST00000522528;ENST00000522971","GO:0016020(membrane);GO:0005886(plasma membrane);GO:0031225(anchored component of membrane);GO:0005576(extracellular region);GO:0006501(C-terminal protein lipidation);GO:0005887(integral component of plasma membrane);GO:0007166(cell surface receptor signaling pathway);GO:0007166(cell surface receptor signaling pathway)","NA","NA","NA","lymphocyte antigen 6 family member E [Source:HGNC Symbol;Acc:HGNC:6727]",{"v":6.50433415113636,"d":"6.50"},{"v":15.4024166098485,"d":"15.40"},{"v":0.422293093083679,"d":"0.42"},{"v":-1.24368344390115,"d":"-1.24"},{"v":0.0241597768771575,"d":"0.02"},{"v":0.394336224290762,"d":"0.39"},"down","yes"]
["MSTRG.9031","RANBP2","ENST00000283195;ENST00000495506;ENST00000495924","GO:0003723(RNA binding);GO:0006810(transport);GO:0051028(mRNA transport);GO:0005634(nucleus);GO:0016020(membrane);GO:0015031(protein transport);GO:0043231(intracellular membrane-bounded organelle);GO:0046872(metal ion binding);GO:0031965(nuclear membrane);GO:0003755(peptidyl-prolyl cis-trans isomerase activity);GO:0000413(protein peptidyl-prolyl isomerization);GO:0006457(protein folding);GO:0043547(positive regulation of GTPase activity);GO:0016874(ligase activity);GO:0005515(protein binding);GO:0046907(intracellular transport);GO:0005643(nuclear pore);GO:0005737(cytoplasm);GO:0005096(GTPase activator activity);GO:0005813(centrosome);GO:0005829(cytosol);GO:0075733(intracellular transport of virus);GO:0043657(host cell);GO:0006607(NLS-bearing protein import into nucleus);GO:0016925(protein sumoylation);GO:0007051(spindle organization);GO:0007062(sister chromatid cohesion);GO:0019789(SUMO transferase activity);GO:0005635(nuclear envelope);GO:0016032(viral process);GO:0005642(annulate lamellae);GO:0006406(mRNA export from nucleus);GO:0060964(regulation of gene silencing by miRNA);GO:0006110(regulation of glycolytic process);GO:0006409(tRNA export from nucleus);GO:0007077(mitotic nuclear envelope disassembly);GO:0019083(viral transcription);GO:1900034(regulation of cellular response to heat);GO:0006511(ubiquitin-dependent protein catabolic process);GO:0008536(Ran GTPase binding);GO:0042405(nuclear inclusion body);GO:0006405(RNA export from nucleus);GO:0000082(G1/S transition of mitotic cell cycle);GO:0044615(nuclear pore nuclear basket);GO:0051642(centrosome localization);GO:0046604(positive regulation of mitotic centrosome separation);GO:0032403(protein complex binding);GO:0001975(response to amphetamine);GO:0033133(positive regulation of glucokinase activity);GO:0090526(regulation of gluconeogenesis involved in cellular glucose homeostasis);GO:0005739(mitochondrion);GO:0044614(nuclear pore cytoplasmic filaments);GO:1990723(cytoplasmic periphery of the nuclear pore complex);GO:1990723(cytoplasmic periphery of the nuclear pore complex)","03013(RNA transport);03013(RNA transport)","K12172","NA","RAN binding protein 2 [Source:HGNC Symbol;Acc:HGNC:9848]",{"v":9.75322659933344,"d":"9.75"},{"v":2.84786844805723,"d":"2.85"},{"v":3.42474618375962,"d":"3.42"},{"v":1.77599707040888,"d":"1.78"},{"v":0.0241769905877054,"d":"0.02"},{"v":0.394336224290762,"d":"0.39"},"up","yes"]
["MSTRG.9381","EEF1B2;SNORA41","ENST00000392222;ENST00000392221;ENST00000236957;ENST00000435123;ENST00000479587;ENST00000429769;ENST00000482103;ENST00000455150;ENST00000384675;ENST00000415904;ENST00000460760;ENST00000445505","GO:0005737(cytoplasm);GO:0006412(translation);GO:0005783(endoplasmic reticulum);GO:0005515(protein binding);GO:0003746(translation elongation factor activity);GO:0006414(translational elongation);GO:0005853(eukaryotic translation elongation factor 1 complex);GO:0005829(cytosol);GO:0045471(response to ethanol);GO:0045471(response to ethanol)","NA","NA","NA","eukaryotic translation elongation factor 1 beta 2 [Source:HGNC Symbol;Acc:HGNC:3208];small nucleolar RNA, H/ACA box 41 [Source:HGNC Symbol;Acc:HGNC:32634]",{"v":118.674133169713,"d":"118.67"},{"v":279.322450843342,"d":"279.32"},{"v":0.42486428431158,"d":"0.42"},{"v":-1.23492602450581,"d":"-1.23"},{"v":0.0242487944545032,"d":"0.02"},{"v":0.394952664796839,"d":"0.39"},"down","yes"]
["MSTRG.4036","MYCBP2","ENST00000429715;ENST00000544440;ENST00000612956;ENST00000498073;ENST00000474882;ENST00000485061;ENST00000486679;ENST00000357337;ENST00000462987;ENST00000482517;ENST00000491491","GO:0005634(nucleus);GO:0016020(membrane);GO:0046872(metal ion binding);GO:0016740(transferase activity);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0016567(protein ubiquitination);GO:0005515(protein binding);GO:0004842(ubiquitin-protein transferase activity);GO:0004842(ubiquitin-protein transferase activity)","NA","NA","NA","MYC binding protein 2, E3 ubiquitin protein ligase [Source:HGNC Symbol;Acc:HGNC:23386]",{"v":8.6076477718407,"d":"8.61"},{"v":2.5171699553465,"d":"2.52"},{"v":3.41957353875051,"d":"3.42"},{"v":1.77381641520098,"d":"1.77"},{"v":0.0243633838433713,"d":"0.02"},{"v":0.395207154176664,"d":"0.40"},"up","yes"]
["MSTRG.3227","ATF7IP","ENST00000261168;ENST00000544627;ENST00000543189;ENST00000536444;ENST00000540793;ENST00000396279;ENST00000545723;ENST00000541654;ENST00000539659;ENST00000535132;ENST00000541056;ENST00000535179;ENST00000538511;ENST00000542508","GO:0005634(nucleus);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0005515(protein binding);GO:0016604(nuclear body);GO:0045893(positive regulation of transcription, DNA-templated);GO:0016032(viral process);GO:0045892(negative regulation of transcription, DNA-templated);GO:0006306(DNA methylation);GO:0045898(regulation of RNA polymerase II transcriptional preinitiation complex assembly);GO:0003714(transcription corepressor activity);GO:0016887(ATPase activity);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0005667(transcription factor complex);GO:0005667(transcription factor complex)","NA","NA","NA","activating transcription factor 7 interacting protein [Source:HGNC Symbol;Acc:HGNC:20092]",{"v":8.71704487125635,"d":"8.72"},{"v":2.54777106240049,"d":"2.55"},{"v":3.4214396261504,"d":"3.42"},{"v":1.77460349016767,"d":"1.77"},{"v":0.0244263723457311,"d":"0.02"},{"v":0.395207154176664,"d":"0.40"},"up","yes"]
["MSTRG.7907","NDUFB7","ENST00000215565;ENST00000593353","GO:0016020(membrane);GO:0055114(oxidation-reduction process);GO:0005743(mitochondrial inner membrane);GO:0005739(mitochondrion);GO:0070469(respiratory chain);GO:0008137(NADH dehydrogenase (ubiquinone) activity);GO:0003954(NADH dehydrogenase activity);GO:0005758(mitochondrial intermembrane space);GO:0032981(mitochondrial respiratory chain complex I assembly);GO:0006120(mitochondrial electron transport, NADH to ubiquinone);GO:0005747(mitochondrial respiratory chain complex I);GO:0005747(mitochondrial respiratory chain complex I)","00190(Oxidative phosphorylation);04723(Retrograde endocannabinoid signaling);05010(Alzheimer's disease);05012(Parkinson's disease);05016(Huntington's disease);04932(Non-alcoholic fatty liver disease (NAFLD));04932(Non-alcoholic fatty liver disease (NAFLD))","K03963","NA","NADH:ubiquinone oxidoreductase subunit B7 [Source:HGNC Symbol;Acc:HGNC:7702]",{"v":17.8147517928437,"d":"17.81"},{"v":42.1024392165725,"d":"42.10"},{"v":0.423128733734539,"d":"0.42"},{"v":-1.24083143564366,"d":"-1.24"},{"v":0.024476253464187,"d":"0.02"},{"v":0.395207154176664,"d":"0.40"},"down","yes"]
["ENSG00000235437","LINC01278","ENST00000609143;ENST00000433061;ENST00000608623;ENST00000609401;ENST00000608788","NA","NA","NA","NA","long intergenic non-protein coding RNA 1278 [Source:HGNC Symbol;Acc:HGNC:28090]",{"v":1.54328016131055,"d":"1.54"},{"v":0.44082479291425,"d":"0.44"},{"v":3.50089238653769,"d":"3.50"},{"v":1.8077227156383,"d":"1.81"},{"v":0.0244872920686089,"d":"0.02"},{"v":0.395207154176664,"d":"0.40"},"up","yes"]
["ENSG00000136205","TNS3","ENST00000311160;ENST00000428457;ENST00000458317;ENST00000434451;ENST00000457718;ENST00000474346","GO:0005829(cytosol);GO:0005925(focal adhesion);GO:0005515(protein binding);GO:0030054(cell junction);GO:0008284(positive regulation of cell proliferation);GO:0016477(cell migration);GO:0048286(lung alveolus development);GO:0035556(intracellular signal transduction);GO:0005622(intracellular);GO:0005622(intracellular)","NA","NA","NA","tensin 3 [Source:HGNC Symbol;Acc:HGNC:21616]",{"v":1.83802265219971,"d":"1.84"},{"v":0.533577222344664,"d":"0.53"},{"v":3.44471723159959,"d":"3.44"},{"v":1.78438556048768,"d":"1.78"},{"v":0.0244904009302253,"d":"0.02"},{"v":0.395207154176664,"d":"0.40"},"up","yes"]
["ENSG00000267041","ZNF850","ENST00000591344;ENST00000614887","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0005622(intracellular);GO:0005622(intracellular)","NA","NA","NA","zinc finger protein 850 [Source:HGNC Symbol;Acc:HGNC:27994]",{"v":0.407221441019108,"d":"0.41"},{"v":0.112916254522293,"d":"0.11"},{"v":3.60640230887848,"d":"3.61"},{"v":1.85056034426033,"d":"1.85"},{"v":0.024497912992214,"d":"0.02"},{"v":0.395207154176664,"d":"0.40"},"up","yes"]
["ENSG00000254126","CD8B2","ENST00000417670;ENST00000416057","NA","NA","NA","NA","CD8b2 molecule [Source:HGNC Symbol;Acc:HGNC:1708]",{"v":1.306001,"d":"1.31"},{"v":3.249822,"d":"3.25"},{"v":0.40186847156552,"d":"0.40"},{"v":-1.31520469912871,"d":"-1.32"},{"v":0.0245026393702917,"d":"0.02"},{"v":0.395207154176664,"d":"0.40"},"down","yes"]
["MSTRG.532","UQCRH","ENST00000311672;ENST00000496387;ENST00000486951;ENST00000489056;ENST00000460947","GO:0016020(membrane);GO:0055114(oxidation-reduction process);GO:0005743(mitochondrial inner membrane);GO:0005739(mitochondrion);GO:0005515(protein binding);GO:1902600(hydrogen ion transmembrane transport);GO:0070469(respiratory chain);GO:0008121(ubiquinol-cytochrome-c reductase activity);GO:0006122(mitochondrial electron transport, ubiquinol to cytochrome c);GO:0005750(mitochondrial respiratory chain complex III);GO:0009060(aerobic respiration);GO:0006119(oxidative phosphorylation);GO:0005746(mitochondrial respiratory chain);GO:0005746(mitochondrial respiratory chain)","00190(Oxidative phosphorylation);04260(Cardiac muscle contraction);05010(Alzheimer's disease);05012(Parkinson's disease);05016(Huntington's disease);04932(Non-alcoholic fatty liver disease (NAFLD));04932(Non-alcoholic fatty liver disease (NAFLD))","K00416","NA","ubiquinol-cytochrome c reductase hinge protein [Source:HGNC Symbol;Acc:HGNC:12590]",{"v":14.9562495767045,"d":"14.96"},{"v":35.1969450965909,"d":"35.20"},{"v":0.424930332324584,"d":"0.42"},{"v":-1.23470176528094,"d":"-1.23"},{"v":0.0246498150405394,"d":"0.02"},{"v":0.396296167440662,"d":"0.40"},"down","yes"]
["ENSG00000114023","FAM162A","ENST00000477892;ENST00000232125;ENST00000469967","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005829(cytosol);GO:0005739(mitochondrion);GO:0005515(protein binding);GO:0006915(apoptotic process);GO:0070062(extracellular exosome);GO:0043065(positive regulation of apoptotic process);GO:0090200(positive regulation of release of cytochrome c from mitochondria);GO:0006919(activation of cysteine-type endopeptidase activity involved in apoptotic process);GO:0071456(cellular response to hypoxia);GO:0051402(neuron apoptotic process);GO:0051402(neuron apoptotic process)","NA","NA","NA","family with sequence similarity 162 member A [Source:HGNC Symbol;Acc:HGNC:17865]",{"v":1.11773263300817,"d":"1.12"},{"v":2.66052134774585,"d":"2.66"},{"v":0.420117896800632,"d":"0.42"},{"v":-1.25113384970668,"d":"-1.25"},{"v":0.0246681343549559,"d":"0.02"},{"v":0.396296167440662,"d":"0.40"},"down","yes"]
["MSTRG.15209","AC004552.1","ENST00000419089","NA","NA","NA","NA",null,{"v":2.744403,"d":"2.74"},{"v":6.838226,"d":"6.84"},{"v":0.401332597080003,"d":"0.40"},{"v":-1.31712975527637,"d":"-1.32"},{"v":0.0247141833252809,"d":"0.02"},{"v":0.396296167440662,"d":"0.40"},"down","yes"]
["MSTRG.14013","MRPS33","ENST00000324787;ENST00000393008;ENST00000496641;ENST00000467334;ENST00000469351;ENST00000496958;ENST00000485202;ENST00000472343","GO:0006412(translation);GO:0030529(intracellular ribonucleoprotein complex);GO:0005840(ribosome);GO:0005739(mitochondrion);GO:0003735(structural constituent of ribosome);GO:0005743(mitochondrial inner membrane);GO:0070125(mitochondrial translational elongation);GO:0070126(mitochondrial translational termination);GO:0005763(mitochondrial small ribosomal subunit);GO:0005763(mitochondrial small ribosomal subunit)","NA","NA","NA","mitochondrial ribosomal protein S33 [Source:HGNC Symbol;Acc:HGNC:16634]",{"v":0.684653938236412,"d":"0.68"},{"v":1.64300040421893,"d":"1.64"},{"v":0.416709537306469,"d":"0.42"},{"v":-1.26288597524698,"d":"-1.26"},{"v":0.0247168394380034,"d":"0.02"},{"v":0.396296167440662,"d":"0.40"},"down","yes"]
["ENSG00000165457","FOLR2","ENST00000298223;ENST00000535625;ENST00000449475;ENST00000538353;ENST00000619261;ENST00000536778;ENST00000541003;ENST00000454954","GO:0005542(folic acid binding);GO:0008517(folic acid transporter activity);GO:0015884(folic acid transport);GO:0008284(positive regulation of cell proliferation);GO:0006810(transport);GO:0016020(membrane);GO:0005886(plasma membrane);GO:0005576(extracellular region);GO:0031225(anchored component of membrane);GO:0006501(C-terminal protein lipidation);GO:0009986(cell surface);GO:0006954(inflammatory response);GO:0046655(folic acid metabolic process);GO:0051870(methotrexate binding);GO:0006898(receptor-mediated endocytosis);GO:0008144(drug binding);GO:0031362(anchored component of external side of plasma membrane);GO:0061714(folic acid receptor activity);GO:0050758(regulation of thymidylate synthase biosynthetic process);GO:0071231(cellular response to folic acid);GO:0071231(cellular response to folic acid)","04144(Endocytosis);01523(Antifolate resistance);01523(Antifolate resistance)","K13649","NA","folate receptor beta [Source:HGNC Symbol;Acc:HGNC:3793]",{"v":1.29867831214689,"d":"1.30"},{"v":3.13709530367232,"d":"3.14"},{"v":0.41397477170255,"d":"0.41"},{"v":-1.27238524467155,"d":"-1.27"},{"v":0.0247502811376175,"d":"0.02"},{"v":0.396296167440662,"d":"0.40"},"down","yes"]
["MSTRG.11087","NIT2","ENST00000394140;ENST00000480073;ENST00000497785;ENST00000460317;ENST00000465368;ENST00000478856","GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0016787(hydrolase activity);GO:0005813(centrosome);GO:0016810(hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds);GO:0006807(nitrogen compound metabolic process);GO:0005576(extracellular region);GO:0070062(extracellular exosome);GO:0043312(neutrophil degranulation);GO:0035580(specific granule lumen);GO:1904724(tertiary granule lumen);GO:0006107(oxaloacetate metabolic process);GO:0006541(glutamine metabolic process);GO:0050152(omega-amidase activity);GO:0006528(asparagine metabolic process);GO:0005739(mitochondrion);GO:0005739(mitochondrion)","00250(Alanine, aspartate and glutamate metabolism);00250(Alanine, aspartate and glutamate metabolism)","K13566","EC:3.5.1.3","nitrilase family member 2 [Source:HGNC Symbol;Acc:HGNC:29878]",{"v":0.35312937888601,"d":"0.35"},{"v":0.846265655548359,"d":"0.85"},{"v":0.417279581855642,"d":"0.42"},{"v":-1.26091376588991,"d":"-1.26"},{"v":0.0247867682935524,"d":"0.02"},{"v":0.396296167440662,"d":"0.40"},"down","yes"]
["ENSG00000197555","SIPA1L1","ENST00000554874;ENST00000358550;ENST00000381232;ENST00000556408;ENST00000555989;ENST00000557712;ENST00000554362;ENST00000555818;ENST00000555652;ENST00000554126;ENST00000555066;ENST00000554960;ENST00000557469;ENST00000556959;ENST00000556780;ENST00000537413;ENST00000553453;ENST00000557151","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005886(plasma membrane);GO:0005856(cytoskeleton);GO:0005096(GTPase activator activity);GO:0030054(cell junction);GO:0045202(synapse);GO:0045211(postsynaptic membrane);GO:0031532(actin cytoskeleton reorganization);GO:0043087(regulation of GTPase activity);GO:0051056(regulation of small GTPase mediated signal transduction);GO:0003674(molecular_function);GO:0008150(biological_process);GO:0005575(cellular_component);GO:0090630(activation of GTPase activity);GO:0014069(postsynaptic density);GO:0043197(dendritic spine);GO:0048814(regulation of dendrite morphogenesis);GO:0043005(neuron projection);GO:0048167(regulation of synaptic plasticity);GO:0048013(ephrin receptor signaling pathway);GO:0050770(regulation of axonogenesis);GO:0061001(regulation of dendritic spine morphogenesis);GO:0046875(ephrin receptor binding);GO:0043547(positive regulation of GTPase activity);GO:0043547(positive regulation of GTPase activity)","04015(Rap1 signaling pathway);04015(Rap1 signaling pathway)","K17701","NA","signal induced proliferation associated 1 like 1 [Source:HGNC Symbol;Acc:HGNC:20284]",{"v":7.32749759506929,"d":"7.33"},{"v":2.14372078416049,"d":"2.14"},{"v":3.41812126337098,"d":"3.42"},{"v":1.77320357985802,"d":"1.77"},{"v":0.0248251293452079,"d":"0.02"},{"v":0.396296167440662,"d":"0.40"},"up","yes"]
["MSTRG.10290","IGLV3-10","ENST00000390315","GO:0016020(membrane);GO:0005886(plasma membrane);GO:0005576(extracellular region);GO:0002376(immune system process);GO:0002377(immunoglobulin production);GO:0006955(immune response);GO:0005615(extracellular space);GO:0003823(antigen binding);GO:0002250(adaptive immune response)","NA","NA","NA","immunoglobulin lambda variable 3-10 [Source:HGNC Symbol;Acc:HGNC:5897]",{"v":3.077213,"d":"3.08"},{"v":7.63388,"d":"7.63"},{"v":0.403099472352198,"d":"0.40"},{"v":-1.31079220015127,"d":"-1.31"},{"v":0.024843159381452,"d":"0.02"},{"v":0.396296167440662,"d":"0.40"},"down","yes"]
["MSTRG.3771","SUDS3","ENST00000543473;ENST00000541280;ENST00000360286;ENST00000541591","GO:0005634(nucleus);GO:0005829(cytosol);GO:0004407(histone deacetylase activity);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0016569(covalent chromatin modification);GO:0005515(protein binding);GO:0016604(nuclear body);GO:0006915(apoptotic process);GO:0005654(nucleoplasm);GO:0016579(protein deubiquitination);GO:0043065(positive regulation of apoptotic process);GO:0021762(substantia nigra development);GO:0019899(enzyme binding);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0045892(negative regulation of transcription, DNA-templated);GO:0042826(histone deacetylase binding);GO:0016575(histone deacetylation);GO:0070822(Sin3-type complex);GO:0016580(Sin3 complex);GO:0016580(Sin3 complex)","NA","NA","NA","SDS3 homolog, SIN3A corepressor complex component [Source:HGNC Symbol;Acc:HGNC:29545]",{"v":2.07660064927587,"d":"2.08"},{"v":4.89029291624498,"d":"4.89"},{"v":0.424637273235238,"d":"0.42"},{"v":-1.23569708315533,"d":"-1.24"},{"v":0.0249052379737627,"d":"0.02"},{"v":0.396741465828953,"d":"0.40"},"down","yes"]
["MSTRG.7984","MAST3","MSTRG.7984.5;MSTRG.7984.3;MSTRG.7984.4;ENST00000262811;ENST00000608648;ENST00000609076;ENST00000601226;MSTRG.7984.2","GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0016740(transferase activity);GO:0000287(magnesium ion binding);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0005515(protein binding);GO:0005622(intracellular);GO:0035556(intracellular signal transduction);GO:0018105(peptidyl-serine phosphorylation);GO:0007010(cytoskeleton organization);GO:0007010(cytoskeleton organization)","NA","NA","NA","microtubule associated serine/threonine kinase 3 [Source:HGNC Symbol;Acc:HGNC:19036]",{"v":13.5738596303452,"d":"13.57"},{"v":3.98931124904106,"d":"3.99"},{"v":3.40255717916421,"d":"3.40"},{"v":1.76661940608005,"d":"1.77"},{"v":0.0251137534354541,"d":"0.03"},{"v":0.399270552137598,"d":"0.40"},"up","yes"]
["ENSG00000154874","CCDC144B","ENST00000618081;ENST00000621104","NA","NA","NA","NA","coiled-coil domain containing 144B (pseudogene) [Source:HGNC Symbol;Acc:HGNC:26704]",{"v":0.342003558787879,"d":"0.34"},{"v":0.0944566506060606,"d":"0.09"},{"v":3.62074620043679,"d":"3.62"},{"v":1.85628705331121,"d":"1.86"},{"v":0.0251327627325053,"d":"0.03"},{"v":0.399270552137598,"d":"0.40"},"up","yes"]
["ENSG00000114648","KLHL18","ENST00000232766;ENST00000461084;ENST00000433449;ENST00000442272;ENST00000483201","GO:0016567(protein ubiquitination);GO:0005515(protein binding);GO:0004842(ubiquitin-protein transferase activity);GO:0031463(Cul3-RING ubiquitin ligase complex);GO:0031463(Cul3-RING ubiquitin ligase complex)","NA","NA","NA","kelch like family member 18 [Source:HGNC Symbol;Acc:HGNC:29120]",{"v":2.69047352024349,"d":"2.69"},{"v":0.784384181625142,"d":"0.78"},{"v":3.43004561192091,"d":"3.43"},{"v":1.77822776113703,"d":"1.78"},{"v":0.0252674034530393,"d":"0.03"},{"v":0.399895240555337,"d":"0.40"},"up","yes"]
["MSTRG.4578","ALKBH1","ENST00000216489;ENST00000557057;ENST00000555100","GO:0005634(nucleus);GO:0006446(regulation of translational initiation);GO:0046872(metal ion binding);GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0016829(lyase activity);GO:0005739(mitochondrion);GO:0006281(DNA repair);GO:0003824(catalytic activity);GO:0008152(metabolic process);GO:0006974(cellular response to DNA damage stimulus);GO:0051213(dioxygenase activity);GO:0000049(tRNA binding);GO:0050918(positive chemotaxis);GO:0003906(DNA-(apurinic or apyrimidinic site) lyase activity);GO:0016706(oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors);GO:0006417(regulation of translation);GO:0070579(methylcytosine dioxygenase activity);GO:0080111(DNA demethylation);GO:0008198(ferrous iron binding);GO:0006307(DNA dealkylation involved in DNA repair);GO:0070129(regulation of mitochondrial translation);GO:0042056(chemoattractant activity);GO:0043734(DNA-N1-methyladenine dioxygenase activity);GO:0103053(1-ethyladenine demethylase activity);GO:1990984(tRNA demethylase activity);GO:0001701(in utero embryonic development);GO:0001764(neuron migration);GO:0001890(placenta development);GO:0002101(tRNA wobble cytosine modification);GO:0006448(regulation of translational elongation);GO:0010468(regulation of gene expression);GO:0030154(cell differentiation);GO:0031175(neuron projection development);GO:0035552(oxidative single-stranded DNA demethylation);GO:0042245(RNA repair);GO:0043524(negative regulation of neuron apoptotic process);GO:0048589(developmental growth);GO:0070989(oxidative demethylation);GO:1990983(tRNA demethylation);GO:0005719(nuclear euchromatin);GO:0005719(nuclear euchromatin)","NA","NA","NA","alkB homolog 1, histone H2A dioxygenase [Source:HGNC Symbol;Acc:HGNC:17911]",{"v":1.22322404219409,"d":"1.22"},{"v":2.90194953270042,"d":"2.90"},{"v":0.42151802724695,"d":"0.42"},{"v":-1.24633376202695,"d":"-1.25"},{"v":0.0253023099910886,"d":"0.03"},{"v":0.399895240555337,"d":"0.40"},"down","yes"]
["MSTRG.11081","CLDND1;CPOX","ENST00000341181;ENST00000264193;ENST00000507411;ENST00000507874;ENST00000512905;ENST00000506927;ENST00000506885;ENST00000510545;ENST00000508902;ENST00000502288;ENST00000513988;ENST00000510489;ENST00000511667;ENST00000503004;ENST00000507944;ENST00000502980;ENST00000512147;ENST00000503799;ENST00000513287;ENST00000513674;ENST00000515041;ENST00000502299","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0009986(cell surface);GO:0016324(apical plasma membrane);GO:0055114(oxidation-reduction process);GO:0006779(porphyrin-containing compound biosynthetic process);GO:0004109(coproporphyrinogen oxidase activity);GO:0005829(cytosol);GO:0016491(oxidoreductase activity);GO:0005739(mitochondrion);GO:0042803(protein homodimerization activity);GO:0006783(heme biosynthetic process);GO:0005758(mitochondrial intermembrane space);GO:0006782(protoporphyrinogen IX biosynthetic process);GO:0005212(structural constituent of eye lens);GO:0042802(identical protein binding);GO:0010035(response to inorganic substance);GO:0010039(response to iron ion);GO:0010288(response to lead ion);GO:0017085(response to insecticide);GO:0046685(response to arsenic-containing substance);GO:0051597(response to methylmercury);GO:0005743(mitochondrial inner membrane);GO:0016324(apical plasma membrane)","00860(Porphyrin and chlorophyll metabolism);00860(Porphyrin and chlorophyll metabolism)","K00228","EC:1.3.3.3","claudin domain containing 1 [Source:HGNC Symbol;Acc:HGNC:1322];coproporphyrinogen oxidase [Source:HGNC Symbol;Acc:HGNC:2321]",{"v":3.0246268234951,"d":"3.02"},{"v":7.0945261719552,"d":"7.09"},{"v":0.42633246395672,"d":"0.43"},{"v":-1.22994917844048,"d":"-1.23"},{"v":0.0253161153138205,"d":"0.03"},{"v":0.399895240555337,"d":"0.40"},"down","yes"]
["MSTRG.15323","MAGEH1","ENST00000342972","GO:0005515(protein binding);GO:0006915(apoptotic process);GO:0005737(cytoplasm)","NA","NA","NA","MAGE family member H1 [Source:HGNC Symbol;Acc:HGNC:24092]",{"v":3.912364,"d":"3.91"},{"v":9.232068,"d":"9.23"},{"v":0.423779807514416,"d":"0.42"},{"v":-1.23861324783996,"d":"-1.24"},{"v":0.0253646561968007,"d":"0.03"},{"v":0.399895240555337,"d":"0.40"},"down","yes"]
["ENSG00000261801","LOXL1-AS1","ENST00000568229;ENST00000565756;ENST00000565416;ENST00000564194;ENST00000568087;ENST00000567257;ENST00000567644;ENST00000562965;ENST00000562739;ENST00000565689","NA","NA","NA","NA","LOXL1 antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:44169]",{"v":0.182470596778015,"d":"0.18"},{"v":0.464738434968017,"d":"0.46"},{"v":0.392630742474684,"d":"0.39"},{"v":-1.34875495652196,"d":"-1.35"},{"v":0.0253906283144633,"d":"0.03"},{"v":0.399895240555337,"d":"0.40"},"down","yes"]
["ENSG00000263887","AC053481.2","ENST00000602493","NA","NA","NA","NA",null,{"v":2.24751,"d":"2.25"},{"v":0.638689,"d":"0.64"},{"v":3.51894270920589,"d":"3.52"},{"v":1.81514202621677,"d":"1.82"},{"v":0.025470410996963,"d":"0.03"},{"v":0.399895240555337,"d":"0.40"},"up","yes"]
["MSTRG.10794","TRANK1","MSTRG.10794.1;ENST00000429976;ENST00000463984;ENST00000463764","NA","NA","NA","NA","tetratricopeptide repeat and ankyrin repeat containing 1 [Source:HGNC Symbol;Acc:HGNC:29011]",{"v":20.9729590890247,"d":"20.97"},{"v":6.18909292364248,"d":"6.19"},{"v":3.38869675213754,"d":"3.39"},{"v":1.76073053863306,"d":"1.76"},{"v":0.0254797155980479,"d":"0.03"},{"v":0.399895240555337,"d":"0.40"},"up","yes"]
["MSTRG.3398","PFDN5","ENST00000552548;ENST00000550846;ENST00000243040;ENST00000334478;ENST00000551018;MSTRG.3398.3;ENST00000351500;ENST00000547130;ENST00000547228;ENST00000550880;ENST00000549759;ENST00000548984;ENST00000628881;ENST00000550964;ENST00000552742;ENST00000553171;ENST00000552341;ENST00000551223;ENST00000550069","GO:0090090(negative regulation of canonical Wnt signaling pathway);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0006457(protein folding);GO:0005515(protein binding);GO:0051082(unfolded protein binding);GO:0016272(prefoldin complex);GO:0003714(transcription corepressor activity);GO:0045892(negative regulation of transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0060041(retina development in camera-type eye);GO:0060041(retina development in camera-type eye)","NA","NA","NA","prefoldin subunit 5 [Source:HGNC Symbol;Acc:HGNC:8869]",{"v":41.5258730671598,"d":"41.53"},{"v":96.8565307890532,"d":"96.86"},{"v":0.428735912063589,"d":"0.43"},{"v":-1.22183882868627,"d":"-1.22"},{"v":0.0254876198766781,"d":"0.03"},{"v":0.399895240555337,"d":"0.40"},"down","yes"]
["MSTRG.11245","XRN1","ENST00000264951;ENST00000392981;ENST00000467077;ENST00000465074;ENST00000463916;ENST00000477237;ENST00000489241;ENST00000468894;ENST00000472625;ENST00000470537;ENST00000498077;ENST00000486211;ENST00000472697","GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005829(cytosol);GO:0016787(hydrolase activity);GO:0003677(DNA binding);GO:0005886(plasma membrane);GO:0004527(exonuclease activity);GO:0004518(nuclease activity);GO:0005634(nucleus);GO:0005515(protein binding);GO:0000956(nuclear-transcribed mRNA catabolic process);GO:0043488(regulation of mRNA stability);GO:0070034(telomerase RNA binding);GO:0071044(histone mRNA catabolic process);GO:0071028(nuclear mRNA surveillance);GO:0090503(RNA phosphodiester bond hydrolysis, exonucleolytic);GO:0032211(negative regulation of telomere maintenance via telomerase);GO:0016075(rRNA catabolic process);GO:0051880(G-quadruplex DNA binding);GO:0004534(5'-3' exoribonuclease activity);GO:0002151(G-quadruplex RNA binding);GO:0008409(5'-3' exonuclease activity);GO:0017148(negative regulation of translation);GO:0033574(response to testosterone);GO:0071409(cellular response to cycloheximide);GO:1905795(cellular response to puromycin);GO:0000932(P-body);GO:0030425(dendrite);GO:0043025(neuronal cell body);GO:0045202(synapse);GO:0090305(nucleic acid phosphodiester bond hydrolysis);GO:0090305(nucleic acid phosphodiester bond hydrolysis)","03008(Ribosome biogenesis in eukaryotes);03018(RNA degradation);03018(RNA degradation)","K12618","EC:3.1.13.-","5'-3' exoribonuclease 1 [Source:HGNC Symbol;Acc:HGNC:30654]",{"v":5.12891138240694,"d":"5.13"},{"v":1.51030641695877,"d":"1.51"},{"v":3.39594093279083,"d":"3.40"},{"v":1.76381136563098,"d":"1.76"},{"v":0.0255001697438959,"d":"0.03"},{"v":0.399895240555337,"d":"0.40"},"up","yes"]
["MSTRG.7712","C19orf70","ENST00000309324;ENST00000590389;ENST00000587589;ENST00000585605;ENST00000590075;ENST00000587950","GO:0005743(mitochondrial inner membrane);GO:0005739(mitochondrion);GO:0061617(MICOS complex);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005654(nucleoplasm);GO:0042407(cristae formation);GO:0044284(mitochondrial crista junction);GO:0044284(mitochondrial crista junction)","NA","NA","NA","chromosome 19 open reading frame 70 [Source:HGNC Symbol;Acc:HGNC:33702]",{"v":2.49121101078749,"d":"2.49"},{"v":5.89037917529666,"d":"5.89"},{"v":0.422928802484438,"d":"0.42"},{"v":-1.24151328011891,"d":"-1.24"},{"v":0.0255787201255422,"d":"0.03"},{"v":0.399895240555337,"d":"0.40"},"down","yes"]
["MSTRG.3537","RPSAP12","ENST00000435879","NA","NA","NA","NA","ribosomal protein SA pseudogene 12 [Source:HGNC Symbol;Acc:HGNC:6504]",{"v":8.193185,"d":"8.19"},{"v":19.252056,"d":"19.25"},{"v":0.425574546427665,"d":"0.43"},{"v":-1.23251622891838,"d":"-1.23"},{"v":0.0255828500314871,"d":"0.03"},{"v":0.399895240555337,"d":"0.40"},"down","yes"]
["MSTRG.1627","RAB18","ENST00000356940;ENST00000621805;ENST00000375802;ENST00000490236;ENST00000484281;ENST00000535776;ENST00000465772;ENST00000423465","GO:0006810(transport);GO:0016020(membrane);GO:0015031(protein transport);GO:0005525(GTP binding);GO:0000166(nucleotide binding);GO:0003924(GTPase activity);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0007275(multicellular organism development);GO:0005789(endoplasmic reticulum membrane);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0001654(eye development);GO:0061024(membrane organization);GO:0005794(Golgi apparatus);GO:0043312(neutrophil degranulation);GO:0019003(GDP binding);GO:0030667(secretory granule membrane);GO:0007420(brain development);GO:0005622(intracellular);GO:0071786(endoplasmic reticulum tubular network organization);GO:0007264(small GTPase mediated signal transduction);GO:0071782(endoplasmic reticulum tubular network);GO:0034389(lipid particle organization);GO:1902593(single-organism nuclear import);GO:1902593(single-organism nuclear import)","NA","NA","NA","RAB18, member RAS oncogene family [Source:HGNC Symbol;Acc:HGNC:14244]",{"v":3.80733981857625,"d":"3.81"},{"v":8.90216286517757,"d":"8.90"},{"v":0.427687054959346,"d":"0.43"},{"v":-1.22537255386107,"d":"-1.23"},{"v":0.0255853064438659,"d":"0.03"},{"v":0.399895240555337,"d":"0.40"},"down","yes"]
["ENSG00000182185","RAD51B","ENST00000487270;ENST00000553334;ENST00000554183;ENST00000468382;ENST00000479335;ENST00000497460;ENST00000556251;ENST00000469165;ENST00000487861;ENST00000460526;ENST00000555782;ENST00000485181","GO:0005524(ATP binding);GO:0003677(DNA binding);GO:0008094(DNA-dependent ATPase activity);GO:0006281(DNA repair);GO:0000724(double-strand break repair via homologous recombination);GO:0033063(Rad51B-Rad51C-Rad51D-XRCC2 complex);GO:0005634(nucleus);GO:0000166(nucleotide binding);GO:0005515(protein binding);GO:0006310(DNA recombination);GO:0006974(cellular response to DNA damage stimulus);GO:0006312(mitotic recombination);GO:0005654(nucleoplasm);GO:0003690(double-stranded DNA binding);GO:0000400(four-way junction DNA binding);GO:0010971(positive regulation of G2/M transition of mitotic cell cycle);GO:0004520(endodeoxyribonuclease activity);GO:0000150(recombinase activity);GO:0003697(single-stranded DNA binding);GO:0000707(meiotic DNA recombinase assembly);GO:0000731(DNA synthesis involved in DNA repair);GO:0000732(strand displacement);GO:0007131(reciprocal meiotic recombination);GO:0007596(blood coagulation);GO:0010212(response to ionizing radiation);GO:0042148(strand invasion);GO:0005657(replication fork);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016021(integral component of membrane)","03440(Homologous recombination);03440(Homologous recombination)","K10869","NA","RAD51 paralog B [Source:HGNC Symbol;Acc:HGNC:9822]",{"v":0.151209395613214,"d":"0.15"},{"v":0.364694004547278,"d":"0.36"},{"v":0.41461991074112,"d":"0.41"},{"v":-1.27013869614928,"d":"-1.27"},{"v":0.0256935792757427,"d":"0.03"},{"v":0.400205268105306,"d":"0.40"},"down","yes"]
["MSTRG.3128","CD69","ENST00000228434;ENST00000416624;ENST00000543147;ENST00000536709","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0030246(carbohydrate binding);GO:0005515(protein binding);GO:0007165(signal transduction);GO:0005887(integral component of plasma membrane);GO:0043234(protein complex);GO:0004888(transmembrane signaling receptor activity);GO:0042803(protein homodimerization activity);GO:0005509(calcium ion binding);GO:0035690(cellular response to drug);GO:0009897(external side of plasma membrane);GO:0009897(external side of plasma membrane)","NA","NA","NA","CD69 molecule [Source:HGNC Symbol;Acc:HGNC:1694]",{"v":4.53571395021186,"d":"4.54"},{"v":10.611167608404,"d":"10.61"},{"v":0.427447206339441,"d":"0.43"},{"v":-1.22618184998972,"d":"-1.23"},{"v":0.0257069739647765,"d":"0.03"},{"v":0.400205268105306,"d":"0.40"},"down","yes"]
["ENSG00000135749","PCNX2","ENST00000258229;ENST00000475463;ENST00000344698;ENST00000520463;ENST00000519530;ENST00000484041;ENST00000497623;ENST00000498302;ENST00000484347;ENST00000522067;ENST00000496675;ENST00000490102;ENST00000429988;ENST00000488780;ENST00000430153;ENST00000517808;ENST00000462233","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0003674(molecular_function);GO:0008150(biological_process);GO:0005575(cellular_component);GO:0005575(cellular_component)","NA","NA","NA","pecanex homolog 2 [Source:HGNC Symbol;Acc:HGNC:8736]",{"v":0.992044127687296,"d":"0.99"},{"v":0.287598621136446,"d":"0.29"},{"v":3.44940502067511,"d":"3.45"},{"v":1.78634753645702,"d":"1.79"},{"v":0.0257085275128355,"d":"0.03"},{"v":0.400205268105306,"d":"0.40"},"up","yes"]
["MSTRG.14367","UBXN2B","MSTRG.14367.3;ENST00000399598;ENST00000523409;ENST00000520732;ENST00000521796;ENST00000638450;ENST00000522978","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005794(Golgi apparatus);GO:0005829(cytosol);GO:0005783(endoplasmic reticulum);GO:0050790(regulation of catalytic activity);GO:0005515(protein binding);GO:0043161(proteasome-mediated ubiquitin-dependent protein catabolic process);GO:0000045(autophagosome assembly);GO:0007030(Golgi organization);GO:0043130(ubiquitin binding);GO:0061025(membrane fusion);GO:0019888(protein phosphatase regulator activity);GO:0031468(nuclear envelope reassembly);GO:0031468(nuclear envelope reassembly)","NA","NA","NA","UBX domain protein 2B [Source:HGNC Symbol;Acc:HGNC:27035]",{"v":9.19208422502128,"d":"9.19"},{"v":2.71106059182979,"d":"2.71"},{"v":3.39058605061173,"d":"3.39"},{"v":1.76153465956719,"d":"1.76"},{"v":0.025870695267726,"d":"0.03"},{"v":0.402130770078101,"d":"0.40"},"up","yes"]
["MSTRG.3889","CRYL1","ENST00000298248;ENST00000480748","GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0003857(3-hydroxyacyl-CoA dehydrogenase activity);GO:0006631(fatty acid metabolic process);GO:0005737(cytoplasm);GO:0070403(NAD+ binding);GO:0005829(cytosol);GO:0042803(protein homodimerization activity);GO:0070062(extracellular exosome);GO:0019640(glucuronate catabolic process to xylulose 5-phosphate);GO:0050104(L-gulonate 3-dehydrogenase activity);GO:0050104(L-gulonate 3-dehydrogenase activity)","00040(Pentose and glucuronate interconversions);00040(Pentose and glucuronate interconversions)","K13247","EC:1.1.1.45","crystallin lambda 1 [Source:HGNC Symbol;Acc:HGNC:18246]",{"v":3.51924383196721,"d":"3.52"},{"v":8.23757846311475,"d":"8.24"},{"v":0.42721824717364,"d":"0.43"},{"v":-1.22695482673662,"d":"-1.23"},{"v":0.0259255428420122,"d":"0.03"},{"v":0.402130770078101,"d":"0.40"},"down","yes"]
["MSTRG.6561","RPS7P1","ENST00000571702","NA","NA","NA","NA","ribosomal protein S7 pseudogene 1 [Source:HGNC Symbol;Acc:HGNC:17081]",{"v":8.707479,"d":"8.71"},{"v":20.459978,"d":"20.46"},{"v":0.42558594149026,"d":"0.43"},{"v":-1.23247760024486,"d":"-1.23"},{"v":0.0259361015059414,"d":"0.03"},{"v":0.402130770078101,"d":"0.40"},"down","yes"]
["MSTRG.10680","SLC6A6","ENST00000618278;ENST00000613060;MSTRG.10680.1;ENST00000622186;ENST00000610642;ENST00000622176;ENST00000452775;ENST00000622810;ENST00000613930;ENST00000621751","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005887(integral component of plasma membrane);GO:0015293(symporter activity);GO:0055085(transmembrane transport);GO:0005328(neurotransmitter:sodium symporter activity);GO:0006836(neurotransmitter transport);GO:0098656(anion transmembrane transport);GO:0005368(taurine transmembrane transporter activity);GO:0005369(taurine:sodium symporter activity);GO:0015734(taurine transport);GO:1903825(organic acid transmembrane transport);GO:0015711(organic anion transport);GO:0042918(alkanesulfonate transport);GO:0005886(plasma membrane);GO:0003333(amino acid transmembrane transport);GO:0015171(amino acid transmembrane transporter activity);GO:0006520(cellular amino acid metabolic process);GO:0006865(amino acid transport);GO:0006865(amino acid transport)","NA","NA","NA","solute carrier family 6 member 6 [Source:HGNC Symbol;Acc:HGNC:11052]",{"v":26.1613546424764,"d":"26.16"},{"v":7.7471886146111,"d":"7.75"},{"v":3.37688365985261,"d":"3.38"},{"v":1.75569247657816,"d":"1.76"},{"v":0.026037608579793,"d":"0.03"},{"v":0.402911766158121,"d":"0.40"},"up","yes"]
["ENSG00000112941","PAPD7","ENST00000230859;ENST00000514697;ENST00000515721;ENST00000514410;ENST00000505457","GO:0016779(nucleotidyltransferase activity);GO:0006397(mRNA processing);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005794(Golgi apparatus);GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0005654(nucleoplasm);GO:0016740(transferase activity);GO:0031965(nuclear membrane);GO:0007062(sister chromatid cohesion);GO:0006302(double-strand break repair);GO:0042493(response to drug);GO:0007076(mitotic chromosome condensation);GO:0004652(polynucleotide adenylyltransferase activity);GO:0043221(SMC family protein binding);GO:0043221(SMC family protein binding)","03018(RNA degradation);03018(RNA degradation)","K03514","EC:2.7.7.19","poly(A) RNA polymerase D7, non-canonical [Source:HGNC Symbol;Acc:HGNC:16705]",{"v":1.80891389933677,"d":"1.81"},{"v":0.527446606927045,"d":"0.53"},{"v":3.42956780000098,"d":"3.43"},{"v":1.778026776957,"d":"1.78"},{"v":0.0260594138175905,"d":"0.03"},{"v":0.402911766158121,"d":"0.40"},"up","yes"]
["MSTRG.15383","RPSAP15","ENST00000448168","NA","NA","NA","NA","ribosomal protein SA pseudogene 15 [Source:HGNC Symbol;Acc:HGNC:31464]",{"v":30.457052,"d":"30.46"},{"v":70.819527,"d":"70.82"},{"v":0.430065735965732,"d":"0.43"},{"v":-1.21737090087858,"d":"-1.22"},{"v":0.0260905578361239,"d":"0.03"},{"v":0.402911766158121,"d":"0.40"},"down","yes"]
["ENSG00000275120","AC048382.5","ENST00000618330","NA","NA","NA","NA",null,{"v":0.21743,"d":"0.22"},{"v":0.54192,"d":"0.54"},{"v":0.401221582521405,"d":"0.40"},{"v":-1.31752888136218,"d":"-1.32"},{"v":0.0261795065994487,"d":"0.03"},{"v":0.4037484862409,"d":"0.40"},"down","yes"]
["MSTRG.4993","GCHFR","ENST00000260447;ENST00000561160;ENST00000559932;ENST00000559445;ENST00000558467","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0042470(melanosome);GO:0030425(dendrite);GO:0005515(protein binding);GO:0009890(negative regulation of biosynthetic process);GO:0031965(nuclear membrane);GO:0050999(regulation of nitric-oxide synthase activity);GO:0006809(nitric oxide biosynthetic process);GO:0004857(enzyme inhibitor activity);GO:0016597(amino acid binding);GO:0019899(enzyme binding);GO:0030742(GTP-dependent protein binding);GO:0044549(GTP cyclohydrolase binding);GO:0006461(protein complex assembly);GO:0042133(neurotransmitter metabolic process);GO:0043105(negative regulation of GTP cyclohydrolase I activity);GO:0051291(protein heterooligomerization);GO:0043234(protein complex);GO:0016787(hydrolase activity);GO:0016787(hydrolase activity)","NA","NA","NA","GTP cyclohydrolase I feedback regulator [Source:HGNC Symbol;Acc:HGNC:4194]",{"v":1.3136687478772,"d":"1.31"},{"v":3.13353177073808,"d":"3.13"},{"v":0.419229433109521,"d":"0.42"},{"v":-1.25418808624078,"d":"-1.25"},{"v":0.0263616310110807,"d":"0.03"},{"v":0.405687339073457,"d":"0.41"},"down","yes"]
["MSTRG.11601","OCIAD2","ENST00000508632;ENST00000620187;ENST00000514155;ENST00000506226;ENST00000510159;ENST00000508069;ENST00000512087;ENST00000514576","GO:0005768(endosome);GO:0005739(mitochondrion);GO:0005743(mitochondrial inner membrane);GO:0005743(mitochondrial inner membrane)","NA","NA","NA","OCIA domain containing 2 [Source:HGNC Symbol;Acc:HGNC:28685]",{"v":2.57850823036649,"d":"2.58"},{"v":6.04724533387032,"d":"6.05"},{"v":0.426393851746744,"d":"0.43"},{"v":-1.22974145913181,"d":"-1.23"},{"v":0.0263750917937191,"d":"0.03"},{"v":0.405687339073457,"d":"0.41"},"down","yes"]
["ENSG00000284707","AC079781.5","ENST00000641390;ENST00000641315;ENST00000641784","NA","NA","NA","NA",null,{"v":0.226204440279395,"d":"0.23"},{"v":0.56220646589057,"d":"0.56"},{"v":0.402351189471066,"d":"0.40"},{"v":-1.31347279714756,"d":"-1.31"},{"v":0.0264322475702776,"d":"0.03"},{"v":0.405707483370184,"d":"0.41"},"down","yes"]
["ENSG00000197183","NOL4L","ENST00000359676;ENST00000621426;ENST00000375678;ENST00000485364;ENST00000475781;ENST00000201961;ENST00000375677;ENST00000419612;ENST00000326071","GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0005515(protein binding);GO:0005515(protein binding)","NA","NA","NA","nucleolar protein 4 like [Source:HGNC Symbol;Acc:HGNC:16106]",{"v":4.9177055388442,"d":"4.92"},{"v":1.4559570373624,"d":"1.46"},{"v":3.37764467813767,"d":"3.38"},{"v":1.75601756731895,"d":"1.76"},{"v":0.0264462727039722,"d":"0.03"},{"v":0.405707483370184,"d":"0.41"},"up","yes"]
["MSTRG.8920","IGKV2D-28","ENST00000453166","GO:0016020(membrane);GO:0005886(plasma membrane);GO:0005576(extracellular region);GO:0006508(proteolysis);GO:0006955(immune response);GO:0002376(immune system process);GO:0003823(antigen binding);GO:0002250(adaptive immune response);GO:0004252(serine-type endopeptidase activity);GO:0006898(receptor-mediated endocytosis);GO:0006956(complement activation);GO:0006958(complement activation, classical pathway);GO:0030449(regulation of complement activation);GO:0038095(Fc-epsilon receptor signaling pathway);GO:0038096(Fc-gamma receptor signaling pathway involved in phagocytosis);GO:0050776(regulation of immune response);GO:0050900(leukocyte migration);GO:0070062(extracellular exosome);GO:0072562(blood microparticle)","NA","NA","NA","immunoglobulin kappa variable 2D-28 [Source:HGNC Symbol;Acc:HGNC:5799]",{"v":8.62474602985075,"d":"8.62"},{"v":2.43604029850746,"d":"2.44"},{"v":3.54047756727795,"d":"3.54"},{"v":1.82394397541385,"d":"1.82"},{"v":0.0264858356512151,"d":"0.03"},{"v":0.405732229526459,"d":"0.41"},"up","yes"]
["ENSG00000174840","PDE12","ENST00000311180;ENST00000487257","GO:0006397(mRNA processing);GO:0046872(metal ion binding);GO:0016787(hydrolase activity);GO:0005739(mitochondrion);GO:0090305(nucleic acid phosphodiester bond hydrolysis);GO:0004527(exonuclease activity);GO:0004518(nuclease activity);GO:0005759(mitochondrial matrix);GO:0004535(poly(A)-specific ribonuclease activity);GO:0090503(RNA phosphodiester bond hydrolysis, exonucleolytic);GO:0090503(RNA phosphodiester bond hydrolysis, exonucleolytic)","NA","NA","NA","phosphodiesterase 12 [Source:HGNC Symbol;Acc:HGNC:25386]",{"v":2.14510434525539,"d":"2.15"},{"v":0.632608116128311,"d":"0.63"},{"v":3.39088970022051,"d":"3.39"},{"v":1.76166385675115,"d":"1.76"},{"v":0.0265177613201225,"d":"0.03"},{"v":0.405732229526459,"d":"0.41"},"up","yes"]
["MSTRG.3836","RILPL2","ENST00000280571","GO:0006810(transport);GO:0005737(cytoplasm);GO:0015031(protein transport);GO:0005829(cytosol);GO:0046983(protein dimerization activity);GO:0005856(cytoskeleton);GO:0042995(cell projection);GO:0005813(centrosome);GO:0005815(microtubule organizing center);GO:0042802(identical protein binding);GO:0005929(cilium);GO:0070062(extracellular exosome);GO:0060271(cilium assembly);GO:0051959(dynein light intermediate chain binding);GO:0036064(ciliary basal body);GO:0016020(membrane);GO:0003382(epithelial cell morphogenesis);GO:0031267(small GTPase binding);GO:1903445(protein transport from ciliary membrane to plasma membrane)","NA","NA","NA","Rab interacting lysosomal protein like 2 [Source:HGNC Symbol;Acc:HGNC:28787]",{"v":7.415238,"d":"7.42"},{"v":2.202033,"d":"2.20"},{"v":3.36745089651245,"d":"3.37"},{"v":1.75165690875381,"d":"1.75"},{"v":0.0267062887808458,"d":"0.03"},{"v":0.407624705288915,"d":"0.41"},"up","yes"]
["ENSG00000205269","TMEM170B","ENST00000379426","GO:0016020(membrane);GO:0016021(integral component of membrane)","NA","NA","NA","transmembrane protein 170B [Source:HGNC Symbol;Acc:HGNC:34244]",{"v":5.16579,"d":"5.17"},{"v":1.534096,"d":"1.53"},{"v":3.36731860326864,"d":"3.37"},{"v":1.75160023010821,"d":"1.75"},{"v":0.0267116507986622,"d":"0.03"},{"v":0.407624705288915,"d":"0.41"},"up","yes"]
["ENSG00000148200","NR6A1","ENST00000487099;ENST00000344523","GO:0005634(nucleus);GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0006355(regulation of transcription, DNA-templated);GO:0006366(transcription from RNA polymerase II promoter);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0042803(protein homodimerization activity);GO:0043565(sequence-specific DNA binding);GO:0003707(steroid hormone receptor activity);GO:0043401(steroid hormone mediated signaling pathway);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0005654(nucleoplasm);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:0005667(transcription factor complex);GO:0001077(transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0007276(gamete generation);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0006367(transcription initiation from RNA polymerase II promoter);GO:0008283(cell proliferation);GO:0007283(spermatogenesis);GO:0004879(RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding);GO:0030518(intracellular steroid hormone receptor signaling pathway);GO:0030518(intracellular steroid hormone receptor signaling pathway)","NA","NA","NA","nuclear receptor subfamily 6 group A member 1 [Source:HGNC Symbol;Acc:HGNC:7985]",{"v":0.522791444834363,"d":"0.52"},{"v":0.149899261931499,"d":"0.15"},{"v":3.4876185385974,"d":"3.49"},{"v":1.80224225268099,"d":"1.80"},{"v":0.0267695349461641,"d":"0.03"},{"v":0.407971928254335,"d":"0.41"},"up","yes"]
["ENSG00000198520","C1orf228","ENST00000427321;ENST00000357508;ENST00000535358;ENST00000427336;ENST00000445071;ENST00000444525;ENST00000440383;ENST00000458657;ENST00000568406;ENST00000418779;ENST00000446792","NA","NA","NA","NA","chromosome 1 open reading frame 228 [Source:HGNC Symbol;Acc:HGNC:34345]",{"v":1.03238902400505,"d":"1.03"},{"v":2.42414957896399,"d":"2.42"},{"v":0.425876782919585,"d":"0.43"},{"v":-1.23149201275627,"d":"-1.23"},{"v":0.0268531966972516,"d":"0.03"},{"v":0.408710580924224,"d":"0.41"},"down","yes"]
["MSTRG.2590","PELI3","ENST00000524466;ENST00000320740;ENST00000532970;ENST00000349459","GO:0016740(transferase activity);GO:0016567(protein ubiquitination);GO:0006468(protein phosphorylation);GO:0005515(protein binding);GO:0008063(Toll signaling pathway);GO:0006955(immune response);GO:0061630(ubiquitin protein ligase activity);GO:0005829(cytosol);GO:0070534(protein K63-linked ubiquitination);GO:0004674(protein serine/threonine kinase activity);GO:0010804(negative regulation of tumor necrosis factor-mediated signaling pathway);GO:2001237(negative regulation of extrinsic apoptotic signaling pathway);GO:2001237(negative regulation of extrinsic apoptotic signaling pathway)","NA","NA","NA","pellino E3 ubiquitin protein ligase family member 3 [Source:HGNC Symbol;Acc:HGNC:30010]",{"v":0.388132475547631,"d":"0.39"},{"v":0.926408114875191,"d":"0.93"},{"v":0.418964891731245,"d":"0.42"},{"v":-1.25509874033592,"d":"-1.26"},{"v":0.0269264779246075,"d":"0.03"},{"v":0.408896877669165,"d":"0.41"},"down","yes"]
["MSTRG.8134","RPS16","ENST00000339471;ENST00000251453;ENST00000601655;ENST00000601390;ENST00000599539;ENST00000602153;ENST00000599705;MSTRG.8134.1;ENST00000595386","GO:0030529(intracellular ribonucleoprotein complex);GO:0003735(structural constituent of ribosome);GO:0006412(translation);GO:0005840(ribosome);GO:0003723(RNA binding);GO:0016020(membrane);GO:0005515(protein binding);GO:0022627(cytosolic small ribosomal subunit);GO:0005925(focal adhesion);GO:0006364(rRNA processing);GO:0042274(ribosomal small subunit biogenesis);GO:0000462(maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA));GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0031012(extracellular matrix);GO:0006413(translational initiation);GO:0000184(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay);GO:0019083(viral transcription);GO:0006614(SRP-dependent cotranslational protein targeting to membrane);GO:0097421(liver regeneration);GO:1990830(cellular response to leukemia inhibitory factor);GO:0015935(small ribosomal subunit);GO:0015935(small ribosomal subunit)","03010(Ribosome);03010(Ribosome)","K02960","NA","ribosomal protein S16 [Source:HGNC Symbol;Acc:HGNC:10396]",{"v":89.8136792225598,"d":"89.81"},{"v":207.25996066578,"d":"207.26"},{"v":0.433338301011212,"d":"0.43"},{"v":-1.2064343386909,"d":"-1.21"},{"v":0.0269370892391117,"d":"0.03"},{"v":0.408896877669165,"d":"0.41"},"down","yes"]
["ENSG00000067208","EVI5","ENST00000540033;ENST00000370331;ENST00000492513;ENST00000474806;ENST00000492613;ENST00000466778;ENST00000491940","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0051301(cell division);GO:0005829(cytosol);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0005096(GTPase activator activity);GO:0007049(cell cycle);GO:0043087(regulation of GTPase activity);GO:0005815(microtubule organizing center);GO:0005819(spindle);GO:0006886(intracellular protein transport);GO:0031338(regulation of vesicle fusion);GO:0090630(activation of GTPase activity);GO:0012505(endomembrane system);GO:0043547(positive regulation of GTPase activity);GO:0042147(retrograde transport, endosome to Golgi);GO:0007275(multicellular organism development);GO:0008283(cell proliferation);GO:0017137(Rab GTPase binding);GO:0017137(Rab GTPase binding)","NA","NA","NA","ecotropic viral integration site 5 [Source:HGNC Symbol;Acc:HGNC:3501]",{"v":1.32783657588207,"d":"1.33"},{"v":0.389290091348478,"d":"0.39"},{"v":3.41091798993014,"d":"3.41"},{"v":1.77016006807256,"d":"1.77"},{"v":0.0269710676220254,"d":"0.03"},{"v":0.408896877669165,"d":"0.41"},"up","yes"]
["ENSG00000163359","COL6A3","ENST00000295550;ENST00000493608;ENST00000353578;ENST00000473258;ENST00000491769","GO:0005615(extracellular space);GO:0007155(cell adhesion);GO:0004867(serine-type endopeptidase inhibitor activity);GO:0010951(negative regulation of endopeptidase activity);GO:0005576(extracellular region);GO:0005581(collagen trimer);GO:0005578(proteinaceous extracellular matrix);GO:0030414(peptidase inhibitor activity);GO:0010466(negative regulation of peptidase activity);GO:0070062(extracellular exosome);GO:0031012(extracellular matrix);GO:0030574(collagen catabolic process);GO:0042383(sarcolemma);GO:0005788(endoplasmic reticulum lumen);GO:0030198(extracellular matrix organization);GO:1903561(extracellular vesicle);GO:0007517(muscle organ development);GO:0005589(collagen type VI trimer);GO:0005589(collagen type VI trimer)","04151(PI3K-Akt signaling pathway);04512(ECM-receptor interaction);04510(Focal adhesion);04974(Protein digestion and absorption);05165(Human papillomavirus infection);05165(Human papillomavirus infection)","K06238","NA","collagen type VI alpha 3 chain [Source:HGNC Symbol;Acc:HGNC:2213]",{"v":0.139010554548233,"d":"0.14"},{"v":0.0388543994601202,"d":"0.04"},{"v":3.57773010211912,"d":"3.58"},{"v":1.8390445570318,"d":"1.84"},{"v":0.027025521466703,"d":"0.03"},{"v":0.409188240929364,"d":"0.41"},"up","yes"]
["MSTRG.5863","SETD1A","ENST00000262519;ENST00000452917;ENST00000640410","GO:0005634(nucleus);GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0016607(nuclear speck);GO:0008168(methyltransferase activity);GO:0016740(transferase activity);GO:0032259(methylation);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0016569(covalent chromatin modification);GO:0005694(chromosome);GO:0005515(protein binding);GO:0018024(histone-lysine N-methyltransferase activity);GO:0051568(histone H3-K4 methylation);GO:0034968(histone lysine methylation);GO:0005654(nucleoplasm);GO:0035097(histone methyltransferase complex);GO:0000790(nuclear chromatin);GO:0045652(regulation of megakaryocyte differentiation);GO:0008013(beta-catenin binding);GO:0008134(transcription factor binding);GO:0042800(histone methyltransferase activity (H3-K4 specific));GO:1990188(euchromatin binding);GO:0010628(positive regulation of gene expression);GO:0019827(stem cell population maintenance);GO:0045646(regulation of erythrocyte differentiation);GO:1902036(regulation of hematopoietic stem cell differentiation);GO:1902275(regulation of chromatin organization);GO:2000179(positive regulation of neural precursor cell proliferation);GO:2000648(positive regulation of stem cell proliferation);GO:0005719(nuclear euchromatin);GO:0048188(Set1C/COMPASS complex);GO:0048188(Set1C/COMPASS complex)","00310(Lysine degradation);00310(Lysine degradation)","K11422","EC:2.1.1.43","SET domain containing 1A [Source:HGNC Symbol;Acc:HGNC:29010]",{"v":3.32143572277518,"d":"3.32"},{"v":0.982812003805621,"d":"0.98"},{"v":3.37952295038522,"d":"3.38"},{"v":1.75681961168894,"d":"1.76"},{"v":0.0271199041410922,"d":"0.03"},{"v":0.410082613008468,"d":"0.41"},"up","yes"]
["MSTRG.5615","DNAJA3","ENST00000355296;ENST00000262375;ENST00000574393;ENST00000573120;ENST00000572009;ENST00000577083;ENST00000575106;ENST00000572139;ENST00000431375;ENST00000570857;ENST00000576911;ENST00000572974;ENST00000576180","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0043231(intracellular membrane-bounded organelle);GO:0046872(metal ion binding);GO:0005524(ATP binding);GO:0005739(mitochondrion);GO:0005829(cytosol);GO:0006457(protein folding);GO:0005886(plasma membrane);GO:0050790(regulation of catalytic activity);GO:0005515(protein binding);GO:0006915(apoptotic process);GO:0030054(cell junction);GO:0045202(synapse);GO:0045211(postsynaptic membrane);GO:0005759(mitochondrial matrix);GO:0051082(unfolded protein binding);GO:0031072(heat shock protein binding);GO:0009408(response to heat);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0008285(negative regulation of cell proliferation);GO:0042645(mitochondrial nucleoid);GO:0005884(actin filament);GO:0071340(skeletal muscle acetylcholine-gated channel clustering);GO:0031594(neuromuscular junction);GO:0019897(extrinsic component of plasma membrane);GO:0030544(Hsp70 protein binding);GO:0030695(GTPase regulator activity);GO:0006264(mitochondrial DNA replication);GO:0006924(activation-induced cell death of T cells);GO:0007005(mitochondrion organization);GO:0007264(small GTPase mediated signal transduction);GO:0007528(neuromuscular junction development);GO:0007569(cell aging);GO:0033077(T cell differentiation in thymus);GO:0042102(positive regulation of T cell proliferation);GO:0043069(negative regulation of programmed cell death);GO:0005634(nucleus);GO:0005634(nucleus)","05203(Viral carcinogenesis);05203(Viral carcinogenesis)","K09504","NA","DnaJ heat shock protein family (Hsp40) member A3 [Source:HGNC Symbol;Acc:HGNC:11808]",{"v":1.87194403577995,"d":"1.87"},{"v":4.34456724310564,"d":"4.34"},{"v":0.430870080040889,"d":"0.43"},{"v":-1.21467517484547,"d":"-1.21"},{"v":0.0272157670515122,"d":"0.03"},{"v":0.410997012703786,"d":"0.41"},"down","yes"]
["MSTRG.1511","LARP4B","ENST00000612396;ENST00000448368;ENST00000609318;ENST00000481118;ENST00000406525;ENST00000614908;ENST00000469487;ENST00000608970;ENST00000316157;ENST00000412411;ENST00000476529","GO:0005730(nucleolus);GO:0005829(cytosol);GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005515(protein binding);GO:0045727(positive regulation of translation);GO:0006417(regulation of translation);GO:0010494(cytoplasmic stress granule);GO:0042788(polysomal ribosome);GO:0042788(polysomal ribosome)","NA","NA","NA","La ribonucleoprotein domain family member 4B [Source:HGNC Symbol;Acc:HGNC:28987]",{"v":4.71014224407915,"d":"4.71"},{"v":1.40220119655656,"d":"1.40"},{"v":3.35910585131865,"d":"3.36"},{"v":1.74807725814055,"d":"1.75"},{"v":0.0273483754436951,"d":"0.03"},{"v":0.411695582685321,"d":"0.41"},"up","yes"]
["MSTRG.14007","KDM7A","ENST00000397560;ENST00000472616;ENST00000478996","GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0005730(nucleolus);GO:0005654(nucleoplasm);GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0016569(covalent chromatin modification);GO:0008270(zinc ion binding);GO:0007399(nervous system development);GO:0051213(dioxygenase activity);GO:0005506(iron ion binding);GO:0016706(oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors);GO:0032454(histone demethylase activity (H3-K9 specific));GO:0033169(histone H3-K9 demethylation);GO:0032452(histone demethylase activity);GO:0035064(methylated histone binding);GO:0071558(histone demethylase activity (H3-K27 specific));GO:0071557(histone H3-K27 demethylation);GO:0051864(histone demethylase activity (H3-K36 specific));GO:0070544(histone H3-K36 demethylation);GO:0030901(midbrain development);GO:0035575(histone demethylase activity (H4-K20 specific));GO:0035574(histone H4-K20 demethylation);GO:0045893(positive regulation of transcription, DNA-templated);GO:0045893(positive regulation of transcription, DNA-templated)","NA","NA","NA","lysine demethylase 7A [Source:HGNC Symbol;Acc:HGNC:22224]",{"v":10.1218382304348,"d":"10.12"},{"v":3.02318515121951,"d":"3.02"},{"v":3.34807090010739,"d":"3.35"},{"v":1.7433300793071,"d":"1.74"},{"v":0.0273671408239514,"d":"0.03"},{"v":0.411695582685321,"d":"0.41"},"up","yes"]
["MSTRG.13042","BICRAL","ENST00000314073;ENST00000614467","NA","NA","NA","NA","BRD4 interacting chromatin remodeling complex associated protein like [Source:HGNC Symbol;Acc:HGNC:21111]",{"v":10.0552619625895,"d":"10.06"},{"v":3.00102743095134,"d":"3.00"},{"v":3.35060648192807,"d":"3.35"},{"v":1.74442225654883,"d":"1.74"},{"v":0.0273683793880193,"d":"0.03"},{"v":0.411695582685321,"d":"0.41"},"up","yes"]
["MSTRG.3378","ATG101","ENST00000336854;ENST00000547409;ENST00000553049;ENST00000552947;ENST00000552544","GO:0005737(cytoplasm);GO:0006914(autophagy);GO:0005515(protein binding);GO:0042802(identical protein binding);GO:0005789(endoplasmic reticulum membrane);GO:0005829(cytosol);GO:0000045(autophagosome assembly);GO:0032403(protein complex binding);GO:0016241(regulation of macroautophagy);GO:0016236(macroautophagy);GO:0000407(pre-autophagosomal structure);GO:0000407(pre-autophagosomal structure)","04140(Autophagy - animal);04136(Autophagy - other eukaryotes);04211(Longevity regulating pathway - mammal);04211(Longevity regulating pathway - mammal)","K19730","NA","autophagy related 101 [Source:HGNC Symbol;Acc:HGNC:25679]",{"v":2.10641353391685,"d":"2.11"},{"v":4.88941906283214,"d":"4.89"},{"v":0.43081059464286,"d":"0.43"},{"v":-1.21487436531451,"d":"-1.21"},{"v":0.0274886727335473,"d":"0.03"},{"v":0.412970189462723,"d":"0.41"},"down","yes"]
["MSTRG.7797","RAVER1;AC011511.1;ZGLP1;FDX2","ENST00000617231;ENST00000293677;ENST00000452032;ENST00000585935;ENST00000403903;ENST00000343376;ENST00000393708;ENST00000453681;ENST00000480726;ENST00000492239;ENST00000611074;ENST00000493771;ENST00000615032;ENST00000460631;ENST00000486454;ENST00000592208;ENST00000403352;MSTRG.7797.13","GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0000398(mRNA splicing, via spliceosome);GO:0051537(2 iron, 2 sulfur cluster binding);GO:0051536(iron-sulfur cluster binding);GO:0009055(electron carrier activity);GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0006355(regulation of transcription, DNA-templated);GO:0006366(transcription from RNA polymerase II promoter);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0043565(sequence-specific DNA binding);GO:0007275(multicellular organism development);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0003682(chromatin binding);GO:0005667(transcription factor complex);GO:0000977(RNA polymerase II regulatory region sequence-specific DNA binding);GO:0001228(transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding);GO:0030154(cell differentiation);GO:0001085(RNA polymerase II transcription factor binding);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0007283(spermatogenesis);GO:0048599(oocyte development);GO:0055114(oxidation-reduction process);GO:0005739(mitochondrion);GO:0005515(protein binding);GO:0005759(mitochondrial matrix);GO:0016125(sterol metabolic process);GO:0006700(C21-steroid hormone biosynthetic process);GO:0044281(small molecule metabolic process);GO:0048599(oocyte development)","NA","NA","NA","ribonucleoprotein, PTB binding 1 [Source:HGNC Symbol;Acc:HGNC:30296];zinc finger, GATA-like protein 1 [Source:HGNC Symbol;Acc:HGNC:37245];ferredoxin 2 [Source:HGNC Symbol;Acc:HGNC:30546]",{"v":4.99765942011444,"d":"5.00"},{"v":1.49107144641285,"d":"1.49"},{"v":3.35172364284594,"d":"3.35"},{"v":1.74490320048952,"d":"1.74"},{"v":0.0278160044830835,"d":"0.03"},{"v":0.417323708965561,"d":"0.42"},"up","yes"]
["MSTRG.14165","AC011899.2","ENST00000438047;ENST00000436151;ENST00000434059","NA","NA","NA","NA",null,{"v":0.970259778206778,"d":"0.97"},{"v":0.28017332046332,"d":"0.28"},{"v":3.46306984762956,"d":"3.46"},{"v":1.79205148595055,"d":"1.79"},{"v":0.0278782268190044,"d":"0.03"},{"v":0.417323708965561,"d":"0.42"},"up","yes"]
["MSTRG.1004","TPM3","ENST00000368533;ENST00000611659;ENST00000509409;ENST00000368545;MSTRG.1004.3;ENST00000312970;ENST00000469717;ENST00000368531;ENST00000330188;ENST00000328159;ENST00000302206;ENST00000341485;ENST00000368527;ENST00000368530;ENST00000504663;ENST00000505010;ENST00000509601;ENST00000323144;ENST00000341372;ENST00000271850","GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0003779(actin binding);GO:0015629(actin cytoskeleton);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0003674(molecular_function);GO:0070062(extracellular exosome);GO:0008307(structural constituent of muscle);GO:0051015(actin filament binding);GO:0007015(actin filament organization);GO:0001725(stress fiber);GO:0006936(muscle contraction);GO:0006928(movement of cell or subcellular component);GO:0030049(muscle filament sliding);GO:0005862(muscle thin filament tropomyosin);GO:0005884(actin filament);GO:0005884(actin filament)","04260(Cardiac muscle contraction);04261(Adrenergic signaling in cardiomyocytes);05200(Pathways in cancer);05216(Thyroid cancer);05410(Hypertrophic cardiomyopathy (HCM));05414(Dilated cardiomyopathy (DCM));05414(Dilated cardiomyopathy (DCM))","K09290","NA","tropomyosin 3 [Source:HGNC Symbol;Acc:HGNC:12012]",{"v":28.5931399336035,"d":"28.59"},{"v":65.5595897282155,"d":"65.56"},{"v":0.436139702096055,"d":"0.44"},{"v":-1.19713776897143,"d":"-1.20"},{"v":0.0278862652335551,"d":"0.03"},{"v":0.417323708965561,"d":"0.42"},"down","yes"]
["MSTRG.9106","PTPN18","ENST00000175756;ENST00000481492;ENST00000462321;ENST00000428843;ENST00000483617;ENST00000462996;ENST00000460992;ENST00000464576;ENST00000490137;ENST00000490812;ENST00000489215;ENST00000347849;ENST00000479295;ENST00000495400;ENST00000420717;ENST00000409022","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016787(hydrolase activity);GO:0004725(protein tyrosine phosphatase activity);GO:0016791(phosphatase activity);GO:0006470(protein dephosphorylation);GO:0016311(dephosphorylation);GO:0035335(peptidyl-tyrosine dephosphorylation);GO:0004721(phosphoprotein phosphatase activity);GO:0005515(protein binding);GO:0005829(cytosol);GO:0038128(ERBB2 signaling pathway);GO:1901185(negative regulation of ERBB signaling pathway);GO:0004726(non-membrane spanning protein tyrosine phosphatase activity);GO:0004726(non-membrane spanning protein tyrosine phosphatase activity)","NA","NA","NA","protein tyrosine phosphatase, non-receptor type 18 [Source:HGNC Symbol;Acc:HGNC:9649]",{"v":13.2662417537236,"d":"13.27"},{"v":3.96648932161413,"d":"3.97"},{"v":3.34458022650746,"d":"3.34"},{"v":1.74182515163244,"d":"1.74"},{"v":0.0279741495443645,"d":"0.03"},{"v":0.41810012697388,"d":"0.42"},"up","yes"]
["ENSG00000103253","HAGHL","ENST00000568141;ENST00000341413;ENST00000569143;ENST00000549114;ENST00000564537;ENST00000569604;ENST00000389701;ENST00000561546;ENST00000563792;ENST00000561750;ENST00000569385;ENST00000561561;ENST00000567696;ENST00000389703","GO:0046872(metal ion binding);GO:0016787(hydrolase activity);GO:0004416(hydroxyacylglutathione hydrolase activity);GO:0019243(methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione);GO:0019243(methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione)","NA","NA","NA","hydroxyacylglutathione hydrolase like [Source:HGNC Symbol;Acc:HGNC:14177]",{"v":0.22071656400818,"d":"0.22"},{"v":0.554344493660532,"d":"0.55"},{"v":0.398157763867574,"d":"0.40"},{"v":-1.32858790519655,"d":"-1.33"},{"v":0.0280747521873989,"d":"0.03"},{"v":0.41898395579529,"d":"0.42"},"down","yes"]
["ENSG00000116984","MTR","ENST00000366577;ENST00000470570","GO:0005737(cytoplasm);GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0005829(cytosol);GO:0008168(methyltransferase activity);GO:0016740(transferase activity);GO:0032259(methylation);GO:0005515(protein binding);GO:0008652(cellular amino acid biosynthetic process);GO:0044237(cellular metabolic process);GO:0009086(methionine biosynthetic process);GO:0031419(cobalamin binding);GO:0008705(methionine synthase activity);GO:0042558(pteridine-containing compound metabolic process);GO:0007399(nervous system development);GO:0009235(cobalamin metabolic process);GO:0031103(axon regeneration);GO:0000096(sulfur amino acid metabolic process);GO:0048678(response to axon injury);GO:0071732(cellular response to nitric oxide);GO:0071732(cellular response to nitric oxide)","00270(Cysteine and methionine metabolism);00450(Selenocompound metabolism);00670(One carbon pool by folate);00670(One carbon pool by folate)","K00548","EC:2.1.1.13","5-methyltetrahydrofolate-homocysteine methyltransferase [Source:HGNC Symbol;Acc:HGNC:7468]",{"v":3.53102957833656,"d":"3.53"},{"v":1.05700469931423,"d":"1.06"},{"v":3.34059969707556,"d":"3.34"},{"v":1.74010711537439,"d":"1.74"},{"v":0.0281204578157238,"d":"0.03"},{"v":0.41898395579529,"d":"0.42"},"up","yes"]
["ENSG00000160299","PCNT","ENST00000359568;ENST00000418394;ENST00000483844;ENST00000465356;ENST00000482575;ENST00000480896;ENST00000490468","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005829(cytosol);GO:0005813(centrosome);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0005815(microtubule organizing center);GO:0005874(microtubule);GO:0005516(calmodulin binding);GO:0000086(G2/M transition of mitotic cell cycle);GO:0010389(regulation of G2/M transition of mitotic cell cycle);GO:0097711(ciliary basal body docking);GO:0000226(microtubule cytoskeleton organization);GO:0060271(cilium assembly);GO:0007052(mitotic spindle organization);GO:0090316(positive regulation of intracellular protein transport);GO:0034451(centriolar satellite);GO:0005814(centriole);GO:0005814(centriole)","NA","NA","NA","pericentrin [Source:HGNC Symbol;Acc:HGNC:16068]",{"v":2.3272715287307,"d":"2.33"},{"v":0.694804035591767,"d":"0.69"},{"v":3.3495365736449,"d":"3.35"},{"v":1.74396150477841,"d":"1.74"},{"v":0.028162888416856,"d":"0.03"},{"v":0.41898395579529,"d":"0.42"},"up","yes"]
["MSTRG.8755","AC114752.2","MSTRG.8755.2;MSTRG.8755.1;ENST00000424119","NA","NA","NA","NA",null,{"v":4.54155838169527,"d":"4.54"},{"v":10.4619650462819,"d":"10.46"},{"v":0.434101850044825,"d":"0.43"},{"v":-1.20389452384044,"d":"-1.20"},{"v":0.0282457144474777,"d":"0.03"},{"v":0.41898395579529,"d":"0.42"},"down","yes"]
["MSTRG.6265","FAM157C;LINC02193","ENST00000570230;ENST00000568739;ENST00000568418;ENST00000566898;ENST00000569162;ENST00000566864;ENST00000565635;ENST00000621799","NA","NA","NA","NA","family with sequence similarity 157 member C (non-protein coding) [Source:HGNC Symbol;Acc:HGNC:34081];long intergenic non-protein coding RNA 2193 [Source:HGNC Symbol;Acc:HGNC:53055]",{"v":1.13621585853901,"d":"1.14"},{"v":0.331917430511844,"d":"0.33"},{"v":3.42318828145564,"d":"3.42"},{"v":1.77534064532819,"d":"1.78"},{"v":0.0282765701499809,"d":"0.03"},{"v":0.41898395579529,"d":"0.42"},"up","yes"]
["ENSG00000115760","BIRC6","ENST00000421745;ENST00000471232;ENST00000462504;ENST00000483194;ENST00000444173;ENST00000465130;ENST00000496555;ENST00000497023;ENST00000470250;ENST00000461788;ENST00000431454","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005794(Golgi apparatus);GO:0043231(intracellular membrane-bounded organelle);GO:0016740(transferase activity);GO:0016567(protein ubiquitination);GO:0051301(cell division);GO:0004842(ubiquitin-protein transferase activity);GO:0010951(negative regulation of endopeptidase activity);GO:0006915(apoptotic process);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0007049(cell cycle);GO:0032465(regulation of cytokinesis);GO:0000922(spindle pole);GO:0005815(microtubule organizing center);GO:0030496(midbody);GO:0004869(cysteine-type endopeptidase inhibitor activity);GO:0030414(peptidase inhibitor activity);GO:0010466(negative regulation of peptidase activity);GO:0005768(endosome);GO:0005802(trans-Golgi network);GO:0042127(regulation of cell proliferation);GO:0043066(negative regulation of apoptotic process);GO:0006468(protein phosphorylation);GO:2001237(negative regulation of extrinsic apoptotic signaling pathway);GO:0061631(ubiquitin conjugating enzyme activity);GO:0001890(placenta development);GO:0008284(positive regulation of cell proliferation);GO:0060711(labyrinthine layer development);GO:0060712(spongiotrophoblast layer development);GO:0060712(spongiotrophoblast layer development)","04120(Ubiquitin mediated proteolysis);04215(Apoptosis - multiple species);04215(Apoptosis - multiple species)","K10586","EC:2.3.2.23","baculoviral IAP repeat containing 6 [Source:HGNC Symbol;Acc:HGNC:13516]",{"v":7.95718751464199,"d":"7.96"},{"v":2.39397661428652,"d":"2.39"},{"v":3.32383677733355,"d":"3.32"},{"v":1.73284953785038,"d":"1.73"},{"v":0.0283434989770761,"d":"0.03"},{"v":0.41898395579529,"d":"0.42"},"up","yes"]
["MSTRG.1393","HLX","ENST00000366903;ENST00000549319","GO:0005634(nucleus);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0043565(sequence-specific DNA binding);GO:0005515(protein binding);GO:0030154(cell differentiation);GO:0007275(multicellular organism development);GO:0001889(liver development);GO:0007519(skeletal muscle tissue development);GO:0008284(positive regulation of cell proliferation);GO:0045627(positive regulation of T-helper 1 cell differentiation);GO:0045629(negative regulation of T-helper 2 cell differentiation);GO:0046622(positive regulation of organ growth);GO:0048484(enteric nervous system development);GO:0048513(animal organ development);GO:0048557(embryonic digestive tract morphogenesis);GO:0048557(embryonic digestive tract morphogenesis)","NA","NA","NA","H2.0 like homeobox [Source:HGNC Symbol;Acc:HGNC:4978]",{"v":5.83813610742049,"d":"5.84"},{"v":1.74686334699647,"d":"1.75"},{"v":3.34206800861584,"d":"3.34"},{"v":1.74074109147645,"d":"1.74"},{"v":0.0283630411991734,"d":"0.03"},{"v":0.41898395579529,"d":"0.42"},"up","yes"]
["MSTRG.10037","SON","ENST00000381679;ENST00000356577;ENST00000300278;ENST00000455528;MSTRG.10037.2;ENST00000475072;ENST00000381692;ENST00000491794;ENST00000436227;ENST00000477419;ENST00000478183;ENST00000470533;ENST00000467616;ENST00000474355;ENST00000457208;ENST00000429093;ENST00000473102;ENST00000465834","GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0006397(mRNA processing);GO:0008380(RNA splicing);GO:0005634(nucleus);GO:0016607(nuclear speck);GO:0003677(DNA binding);GO:0007049(cell cycle);GO:0043484(regulation of RNA splicing);GO:0051726(regulation of cell cycle);GO:0005515(protein binding);GO:0043066(negative regulation of apoptotic process);GO:0000226(microtubule cytoskeleton organization);GO:0000281(mitotic cytokinesis);GO:0048024(regulation of mRNA splicing, via spliceosome);GO:0050733(RS domain binding);GO:0050733(RS domain binding)","NA","NA","NA","SON DNA binding protein [Source:HGNC Symbol;Acc:HGNC:11183]",{"v":23.1544097178319,"d":"23.15"},{"v":6.9681227270933,"d":"6.97"},{"v":3.32290498096474,"d":"3.32"},{"v":1.73244503950876,"d":"1.73"},{"v":0.0283722156196252,"d":"0.03"},{"v":0.41898395579529,"d":"0.42"},"up","yes"]
["MSTRG.6690","SLFN5","ENST00000299977;ENST00000542451;ENST00000592325","GO:0005634(nucleus);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0030154(cell differentiation);GO:0030154(cell differentiation)","NA","NA","NA","schlafen family member 5 [Source:HGNC Symbol;Acc:HGNC:28286]",{"v":21.0791141284901,"d":"21.08"},{"v":6.34781271463255,"d":"6.35"},{"v":3.32068935806817,"d":"3.32"},{"v":1.73148276874966,"d":"1.73"},{"v":0.0284034312773582,"d":"0.03"},{"v":0.41898395579529,"d":"0.42"},"up","yes"]
["ENSG00000232859","LYRM9","ENST00000508816;ENST00000582343;ENST00000503642;ENST00000460380;ENST00000379102;ENST00000508862;ENST00000379103","NA","NA","NA","NA","LYR motif containing 9 [Source:HGNC Symbol;Acc:HGNC:27314]",{"v":0.276572875836431,"d":"0.28"},{"v":0.660875563568773,"d":"0.66"},{"v":0.418494632095214,"d":"0.42"},{"v":-1.25671897700847,"d":"-1.26"},{"v":0.0284468620450903,"d":"0.03"},{"v":0.41898395579529,"d":"0.42"},"down","yes"]
["MSTRG.4289","GZMH","ENST00000216338;ENST00000382548;ENST00000557220","GO:0016020(membrane);GO:0016787(hydrolase activity);GO:0008233(peptidase activity);GO:0006508(proteolysis);GO:0004252(serine-type endopeptidase activity);GO:0006915(apoptotic process);GO:0008236(serine-type peptidase activity);GO:0019835(cytolysis);GO:0030141(secretory granule);GO:0030141(secretory granule)","NA","NA","NA","granzyme H [Source:HGNC Symbol;Acc:HGNC:4710]",{"v":51.4770032996845,"d":"51.48"},{"v":117.68146685489,"d":"117.68"},{"v":0.437426594649432,"d":"0.44"},{"v":-1.19288715890355,"d":"-1.19"},{"v":0.0284915720550379,"d":"0.03"},{"v":0.41898395579529,"d":"0.42"},"down","yes"]
["MSTRG.817","RSBN1","ENST00000612242;ENST00000261441;ENST00000615321;ENST00000476412;ENST00000369581","GO:0005634(nucleus);GO:0005634(nucleus)","NA","NA","NA","round spermatid basic protein 1 [Source:HGNC Symbol;Acc:HGNC:25642]",{"v":4.66435458644963,"d":"4.66"},{"v":1.39616743202816,"d":"1.40"},{"v":3.34082752501532,"d":"3.34"},{"v":1.74020550340678,"d":"1.74"},{"v":0.0285226472592237,"d":"0.03"},{"v":0.41898395579529,"d":"0.42"},"up","yes"]
["MSTRG.5020","AC068724.1","ENST00000487100","NA","NA","NA","NA",null,{"v":1.325123,"d":"1.33"},{"v":3.160951,"d":"3.16"},{"v":0.419216558561015,"d":"0.42"},{"v":-1.25423239212922,"d":"-1.25"},{"v":0.0285359383277346,"d":"0.03"},{"v":0.41898395579529,"d":"0.42"},"down","yes"]
["ENSG00000100139","MICALL1","ENST00000215957;ENST00000454685;ENST00000489812;ENST00000402631;ENST00000424008","GO:0005622(intracellular);GO:0046872(metal ion binding);GO:0032456(endocytic recycling);GO:0017137(Rab GTPase binding);GO:0006810(transport);GO:0016020(membrane);GO:0015031(protein transport);GO:0005515(protein binding);GO:0005768(endosome);GO:0031902(late endosome membrane);GO:0045296(cadherin binding);GO:0006897(endocytosis);GO:0042802(identical protein binding);GO:1990126(retrograde transport, endosome to plasma membrane);GO:0005770(late endosome);GO:0055038(recycling endosome membrane);GO:0019898(extrinsic component of membrane);GO:0006612(protein targeting to membrane);GO:0031175(neuron projection development);GO:0070300(phosphatidic acid binding);GO:0006898(receptor-mediated endocytosis);GO:0097320(plasma membrane tubulation);GO:0036010(protein localization to endosome);GO:0032458(slow endocytic recycling);GO:1990090(cellular response to nerve growth factor stimulus);GO:0010008(endosome membrane);GO:0010008(endosome membrane)","NA","NA","NA","MICAL like 1 [Source:HGNC Symbol;Acc:HGNC:29804]",{"v":2.15681581769437,"d":"2.16"},{"v":0.641633644772118,"d":"0.64"},{"v":3.3614443931792,"d":"3.36"},{"v":1.74908128392967,"d":"1.75"},{"v":0.0285383887913609,"d":"0.03"},{"v":0.41898395579529,"d":"0.42"},"up","yes"]
["ENSG00000163945","UVSSA","ENST00000389851;ENST00000512728;ENST00000503548;ENST00000507531;ENST00000511216;ENST00000511563;ENST00000324803;ENST00000505716","GO:0016567(protein ubiquitination);GO:0005694(chromosome);GO:0006281(DNA repair);GO:0006974(cellular response to DNA damage stimulus);GO:0005515(protein binding);GO:0005654(nucleoplasm);GO:0009411(response to UV);GO:0006283(transcription-coupled nucleotide-excision repair);GO:0000993(RNA polymerase II core binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0033147(negative regulation of intracellular estrogen receptor signaling pathway);GO:0005886(plasma membrane);GO:0005783(endoplasmic reticulum);GO:0006469(negative regulation of protein kinase activity);GO:0043627(response to estrogen);GO:0051493(regulation of cytoskeleton organization);GO:0051493(regulation of cytoskeleton organization)","NA","NA","NA","UV stimulated scaffold protein A [Source:HGNC Symbol;Acc:HGNC:29304]",{"v":0.31737094389146,"d":"0.32"},{"v":0.091454054143156,"d":"0.09"},{"v":3.47027747282443,"d":"3.47"},{"v":1.79505102091986,"d":"1.80"},{"v":0.0285754891213855,"d":"0.03"},{"v":0.418998933291225,"d":"0.42"},"up","yes"]
["ENSG00000138336","TET1","ENST00000373644","GO:0005634(nucleus);GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0016569(covalent chromatin modification);GO:0003677(DNA binding);GO:0051213(dioxygenase activity);GO:0005506(iron ion binding);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0008284(positive regulation of cell proliferation);GO:0006493(protein O-linked glycosylation);GO:0070579(methylcytosine dioxygenase activity);GO:0080111(DNA demethylation);GO:0019827(stem cell population maintenance);GO:0090310(negative regulation of methylation-dependent chromatin silencing);GO:0001826(inner cell mass cell differentiation);GO:0031062(positive regulation of histone methylation)","NA","NA","NA","tet methylcytosine dioxygenase 1 [Source:HGNC Symbol;Acc:HGNC:29484]",{"v":0.321619,"d":"0.32"},{"v":0.09235,"d":"0.09"},{"v":3.48260963724959,"d":"3.48"},{"v":1.80016877152761,"d":"1.80"},{"v":0.0287095901392049,"d":"0.03"},{"v":0.420434388759882,"d":"0.42"},"up","yes"]
["MSTRG.8217","BCL3","ENST00000164227;ENST00000473473;ENST00000403534;ENST00000464319;ENST00000444487;ENST00000477832;ENST00000487394;ENST00000474300;ENST00000473468","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0043231(intracellular membrane-bounded organelle);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0006974(cellular response to DNA damage stimulus);GO:0048471(perinuclear region of cytoplasm);GO:0030496(midbody);GO:0045893(positive regulation of transcription, DNA-templated);GO:0045727(positive regulation of translation);GO:0009615(response to virus);GO:0043234(protein complex);GO:0042981(regulation of apoptotic process);GO:0043066(negative regulation of apoptotic process);GO:0008134(transcription factor binding);GO:0030674(protein binding, bridging);GO:0045892(negative regulation of transcription, DNA-templated);GO:0007249(I-kappaB kinase/NF-kappaB signaling);GO:0030330(DNA damage response, signal transduction by p53 class mediator);GO:0046426(negative regulation of JAK-STAT cascade);GO:0000060(protein import into nucleus, translocation);GO:0051101(regulation of DNA binding);GO:0042771(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator);GO:0045415(negative regulation of interleukin-8 biosynthetic process);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0002268(follicular dendritic cell differentiation);GO:0002315(marginal zone B cell differentiation);GO:0002455(humoral immune response mediated by circulating immunoglobulin);GO:0002467(germinal center formation);GO:0010225(response to UV-C);GO:0019730(antimicrobial humoral response);GO:0030198(extracellular matrix organization);GO:0032729(positive regulation of interferon-gamma production);GO:0042088(T-helper 1 type immune response);GO:0042345(regulation of NF-kappaB import into nucleus);GO:0042536(negative regulation of tumor necrosis factor biosynthetic process);GO:0042742(defense response to bacterium);GO:0042832(defense response to protozoan);GO:0045064(T-helper 2 cell differentiation);GO:0045082(positive regulation of interleukin-10 biosynthetic process);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0048536(spleen development);GO:0051457(maintenance of protein location in nucleus);GO:0032996(Bcl3-Bcl10 complex);GO:0033257(Bcl3/NF-kappaB2 complex);GO:0033257(Bcl3/NF-kappaB2 complex)","04668(TNF signaling pathway);04668(TNF signaling pathway)","K09258","NA","B-cell CLL/lymphoma 3 [Source:HGNC Symbol;Acc:HGNC:998]",{"v":11.2005537393584,"d":"11.20"},{"v":3.3592154796422,"d":"3.36"},{"v":3.3342766509731,"d":"3.33"},{"v":1.73737381231129,"d":"1.74"},{"v":0.0288242551947204,"d":"0.03"},{"v":0.421336154750218,"d":"0.42"},"up","yes"]
["ENSG00000205189","ZBTB10","ENST00000455036;ENST00000430430;ENST00000426744","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0005654(nucleoplasm);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0005515(protein binding)","NA","NA","NA","zinc finger and BTB domain containing 10 [Source:HGNC Symbol;Acc:HGNC:30953]",{"v":0.332795901722788,"d":"0.33"},{"v":0.0963489798355521,"d":"0.10"},{"v":3.4540677264129,"d":"3.45"},{"v":1.78829637111296,"d":"1.79"},{"v":0.0288596120284608,"d":"0.03"},{"v":0.421336154750218,"d":"0.42"},"up","yes"]
["ENSG00000183647","ZNF530","ENST00000598297;ENST00000600619;ENST00000332854;ENST00000597700","GO:0003676(nucleic acid binding);GO:0006355(regulation of transcription, DNA-templated);GO:0005622(intracellular);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0003677(DNA binding)","NA","NA","NA","zinc finger protein 530 [Source:HGNC Symbol;Acc:HGNC:29297]",{"v":0.179169780633592,"d":"0.18"},{"v":0.430505597529388,"d":"0.43"},{"v":0.416184555234177,"d":"0.42"},{"v":-1.26470466777784,"d":"-1.26"},{"v":0.0289104612068835,"d":"0.03"},{"v":0.421336154750218,"d":"0.42"},"down","yes"]
["ENSG00000107554","DNMBP","ENST00000324109;ENST00000636706;ENST00000543621","GO:0005737(cytoplasm);GO:0035556(intracellular signal transduction);GO:0005089(Rho guanyl-nucleotide exchange factor activity);GO:0035023(regulation of Rho protein signal transduction);GO:0043547(positive regulation of GTPase activity);GO:0005085(guanyl-nucleotide exchange factor activity);GO:0005794(Golgi apparatus);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0030054(cell junction);GO:0045202(synapse);GO:0007264(small GTPase mediated signal transduction);GO:0005795(Golgi stack);GO:0005795(Golgi stack)","NA","NA","NA","dynamin binding protein [Source:HGNC Symbol;Acc:HGNC:30373]",{"v":1.31790076823071,"d":"1.32"},{"v":0.39222139534334,"d":"0.39"},{"v":3.36009402821347,"d":"3.36"},{"v":1.74850160566451,"d":"1.75"},{"v":0.0289162934070373,"d":"0.03"},{"v":0.421336154750218,"d":"0.42"},"up","yes"]
["MSTRG.9991","SCAF4","ENST00000399804;ENST00000286835;ENST00000467731;ENST00000485790;ENST00000472318","GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005654(nucleoplasm)","NA","NA","NA","SR-related CTD associated factor 4 [Source:HGNC Symbol;Acc:HGNC:19304]",{"v":5.76112915251652,"d":"5.76"},{"v":1.72622304050161,"d":"1.73"},{"v":3.33741875606204,"d":"3.34"},{"v":1.73873271720378,"d":"1.74"},{"v":0.0289992139409313,"d":"0.03"},{"v":0.422014876561448,"d":"0.42"},"up","yes"]
["MSTRG.9890","HELZ2","MSTRG.9890.2;ENST00000427522;ENST00000478861;ENST00000370082;ENST00000479540","GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0005634(nucleus);GO:0016020(membrane);GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0016787(hydrolase activity);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0004386(helicase activity);GO:0003677(DNA binding);GO:0030374(ligand-dependent nuclear receptor transcription coactivator activity);GO:0005515(protein binding);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0005654(nucleoplasm);GO:0019216(regulation of lipid metabolic process);GO:0019216(regulation of lipid metabolic process)","NA","NA","NA","helicase with zinc finger 2 [Source:HGNC Symbol;Acc:HGNC:30021]",{"v":6.59822953845516,"d":"6.60"},{"v":1.99323918125311,"d":"1.99"},{"v":3.31030495512685,"d":"3.31"},{"v":1.72696412850787,"d":"1.73"},{"v":0.0291446924087887,"d":"0.03"},{"v":0.422869870024088,"d":"0.42"},"up","yes"]
["ENSG00000166341","DCHS1","ENST00000299441","GO:0005622(intracellular);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005509(calcium ion binding);GO:0007155(cell adhesion);GO:0007156(homophilic cell adhesion via plasma membrane adhesion molecules);GO:0005886(plasma membrane);GO:0022008(neurogenesis);GO:0007157(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules);GO:0035329(hippo signaling);GO:0016339(calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules);GO:0001658(branching involved in ureteric bud morphogenesis);GO:0001822(kidney development);GO:0003007(heart morphogenesis);GO:0003183(mitral valve morphogenesis);GO:0003192(mitral valve formation);GO:0003273(cell migration involved in endocardial cushion formation);GO:0007389(pattern specification process);GO:0016477(cell migration);GO:0021915(neural tube development);GO:0036342(post-anal tail morphogenesis);GO:0043931(ossification involved in bone maturation);GO:0048565(digestive tract development);GO:0072006(nephron development);GO:0072137(condensed mesenchymal cell proliferation);GO:0072659(protein localization to plasma membrane);GO:0090102(cochlea development);GO:0098609(cell-cell adhesion);GO:0045177(apical part of cell)","04392(Hippo signaling pathway - multiple species)","K16507","NA","dachsous cadherin-related 1 [Source:HGNC Symbol;Acc:HGNC:13681]",{"v":0.68475,"d":"0.68"},{"v":0.202955,"d":"0.20"},{"v":3.37390061836368,"d":"3.37"},{"v":1.7544174782178,"d":"1.75"},{"v":0.0291620944098584,"d":"0.03"},{"v":0.422869870024088,"d":"0.42"},"up","yes"]
["ENSG00000196505","GDAP2","ENST00000369443;ENST00000493555;ENST00000369442;ENST00000491626;ENST00000464026;ENST00000494224","GO:0005765(lysosomal membrane);GO:0005515(protein binding);GO:0032526(response to retinoic acid);GO:0032526(response to retinoic acid)","NA","NA","NA","ganglioside induced differentiation associated protein 2 [Source:HGNC Symbol;Acc:HGNC:18010]",{"v":1.88267543702363,"d":"1.88"},{"v":0.562963358136433,"d":"0.56"},{"v":3.34422375775186,"d":"3.34"},{"v":1.74167137953578,"d":"1.74"},{"v":0.029229000960559,"d":"0.03"},{"v":0.422869870024088,"d":"0.42"},"up","yes"]
["ENSG00000106638","TBL2","ENST00000305632;ENST00000452475;ENST00000424598;ENST00000469518;ENST00000459913;ENST00000465279;ENST00000450285;ENST00000496056;ENST00000435792;ENST00000488915;ENST00000495885;ENST00000426966","GO:0003723(RNA binding);GO:0005783(endoplasmic reticulum);GO:0019901(protein kinase binding);GO:0042149(cellular response to glucose starvation);GO:0030176(integral component of endoplasmic reticulum membrane);GO:0071456(cellular response to hypoxia);GO:0031369(translation initiation factor binding);GO:0030968(endoplasmic reticulum unfolded protein response);GO:0051219(phosphoprotein binding);GO:0051219(phosphoprotein binding)","NA","NA","NA","transducin beta like 2 [Source:HGNC Symbol;Acc:HGNC:11586]",{"v":0.793926385632524,"d":"0.79"},{"v":1.84659419340833,"d":"1.85"},{"v":0.42994090876412,"d":"0.43"},{"v":-1.21778970598224,"d":"-1.22"},{"v":0.0292443796540973,"d":"0.03"},{"v":0.422869870024088,"d":"0.42"},"down","yes"]
["MSTRG.8232","SNRPD2","ENST00000342669;ENST00000587367;ENST00000588599;ENST00000590212;ENST00000391932","GO:0003723(RNA binding);GO:0006397(mRNA processing);GO:0008380(RNA splicing);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0030529(intracellular ribonucleoprotein complex);GO:0005515(protein binding);GO:0005681(spliceosomal complex);GO:0000387(spliceosomal snRNP assembly);GO:0005685(U1 snRNP);GO:0005654(nucleoplasm);GO:0070062(extracellular exosome);GO:0030532(small nuclear ribonucleoprotein complex);GO:0005682(U5 snRNP);GO:0046540(U4/U6 x U5 tri-snRNP complex);GO:0000398(mRNA splicing, via spliceosome);GO:0034709(methylosome);GO:0000245(spliceosomal complex assembly);GO:0051170(nuclear import);GO:0034719(SMN-Sm protein complex);GO:0071013(catalytic step 2 spliceosome);GO:0071011(precatalytic spliceosome);GO:0005686(U2 snRNP);GO:0005689(U12-type spliceosomal complex);GO:0005687(U4 snRNP);GO:0034715(pICln-Sm protein complex);GO:0034715(pICln-Sm protein complex)","03040(Spliceosome);03040(Spliceosome)","K11096","NA","small nuclear ribonucleoprotein D2 polypeptide [Source:HGNC Symbol;Acc:HGNC:11159]",{"v":17.2315092120647,"d":"17.23"},{"v":39.2194149185323,"d":"39.22"},{"v":0.43936171021058,"d":"0.44"},{"v":-1.18651894860435,"d":"-1.19"},{"v":0.0292656899957222,"d":"0.03"},{"v":0.422869870024088,"d":"0.42"},"down","yes"]
["ENSG00000166145","SPINT1","ENST00000344051;ENST00000564375;ENST00000566928;ENST00000562057;ENST00000566642;ENST00000568200;ENST00000568823;ENST00000563135","GO:0004867(serine-type endopeptidase inhibitor activity);GO:0010951(negative regulation of endopeptidase activity);GO:0005576(extracellular region);GO:0005615(extracellular space);GO:0030414(peptidase inhibitor activity);GO:0010466(negative regulation of peptidase activity);GO:0070062(extracellular exosome);GO:0016020(membrane);GO:0001843(neural tube closure);GO:0001892(embryonic placenta development);GO:0030198(extracellular matrix organization);GO:0045687(positive regulation of glial cell differentiation);GO:0060670(branching involved in labyrinthine layer morphogenesis);GO:0060674(placenta blood vessel development);GO:0071773(cellular response to BMP stimulus);GO:2000178(negative regulation of neural precursor cell proliferation);GO:0005886(plasma membrane);GO:0016021(integral component of membrane);GO:0016021(integral component of membrane)","05202(Transcriptional misregulation in cancers);05215(Prostate cancer);05215(Prostate cancer)","K15619","NA","serine peptidase inhibitor, Kunitz type 1 [Source:HGNC Symbol;Acc:HGNC:11246]",{"v":2.38672291727837,"d":"2.39"},{"v":0.705115128458498,"d":"0.71"},{"v":3.38486981905516,"d":"3.38"},{"v":1.75910034930542,"d":"1.76"},{"v":0.0292764466976119,"d":"0.03"},{"v":0.422869870024088,"d":"0.42"},"up","yes"]
["MSTRG.192","CROCCP3","ENST00000263511;ENST00000591348;ENST00000590118;ENST00000420820;ENST00000591316","NA","NA","NA","NA","ciliary rootlet coiled-coil, rootletin pseudogene 3 [Source:HGNC Symbol;Acc:HGNC:29405]",{"v":0.781370639659475,"d":"0.78"},{"v":0.230110386907383,"d":"0.23"},{"v":3.39563393969681,"d":"3.40"},{"v":1.76368094008965,"d":"1.76"},{"v":0.0293773798939019,"d":"0.03"},{"v":0.423385761684082,"d":"0.42"},"up","yes"]
["ENSG00000106261","ZKSCAN1","ENST00000324306;ENST00000432317;ENST00000482979;ENST00000426572;ENST00000620510","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0005622(intracellular);GO:0005515(protein binding);GO:0005515(protein binding)","NA","NA","NA","zinc finger with KRAB and SCAN domains 1 [Source:HGNC Symbol;Acc:HGNC:13101]",{"v":4.96125388874891,"d":"4.96"},{"v":1.49925969028007,"d":"1.50"},{"v":3.30913578275563,"d":"3.31"},{"v":1.726454490529,"d":"1.73"},{"v":0.0293850791283364,"d":"0.03"},{"v":0.423385761684082,"d":"0.42"},"up","yes"]
["ENSG00000236438","FAM157A","ENST00000437428;ENST00000634862","NA","NA","NA","NA","family with sequence similarity 157 member A (non-protein coding) [Source:HGNC Symbol;Acc:HGNC:34079]",{"v":8.81234918262586,"d":"8.81"},{"v":2.66730554985193,"d":"2.67"},{"v":3.30383940569353,"d":"3.30"},{"v":1.72414356138192,"d":"1.72"},{"v":0.0294487469767998,"d":"0.03"},{"v":0.423454468339715,"d":"0.42"},"up","yes"]
["MSTRG.868","NBPF10;NOTCH2NL;AC239799.1","ENST00000583866;ENST00000362074;ENST00000479995;ENST00000578207;ENST00000612520;ENST00000579793","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005737(cytoplasm);GO:0005509(calcium ion binding);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0007275(multicellular organism development);GO:0030154(cell differentiation);GO:0007219(Notch signaling pathway);GO:0007219(Notch signaling pathway)","NA","NA","NA","NBPF member 10 [Source:HGNC Symbol;Acc:HGNC:31992];notch 2 N-terminal like [Source:HGNC Symbol;Acc:HGNC:31862]",{"v":2.91199788240036,"d":"2.91"},{"v":0.880164934498917,"d":"0.88"},{"v":3.30846841115998,"d":"3.31"},{"v":1.72616350494977,"d":"1.73"},{"v":0.0294627753740196,"d":"0.03"},{"v":0.423454468339715,"d":"0.42"},"up","yes"]
["MSTRG.2385","PTPRJ","ENST00000418331;ENST00000440289;ENST00000613246;ENST00000615445;ENST00000527952;MSTRG.2385.7;ENST00000534219;ENST00000527026","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016787(hydrolase activity);GO:0004725(protein tyrosine phosphatase activity);GO:0016791(phosphatase activity);GO:0006470(protein dephosphorylation);GO:0016311(dephosphorylation);GO:0005886(plasma membrane);GO:0004721(phosphoprotein phosphatase activity);GO:0042995(cell projection);GO:0005515(protein binding);GO:0030054(cell junction);GO:0070062(extracellular exosome);GO:0019901(protein kinase binding);GO:0008285(negative regulation of cell proliferation);GO:0050852(T cell receptor signaling pathway);GO:0032587(ruffle membrane);GO:0035335(peptidyl-tyrosine dephosphorylation);GO:0005887(integral component of plasma membrane);GO:0043312(neutrophil degranulation);GO:0035579(specific granule membrane);GO:0009986(cell surface);GO:0045785(positive regulation of cell adhesion);GO:0030308(negative regulation of cell growth);GO:0043116(negative regulation of vascular permeability);GO:0048008(platelet-derived growth factor receptor signaling pathway);GO:0005911(cell-cell junction);GO:0030155(regulation of cell adhesion);GO:0008013(beta-catenin binding);GO:0045295(gamma-catenin binding);GO:0070097(delta-catenin binding);GO:0051897(positive regulation of protein kinase B signaling);GO:0010642(negative regulation of platelet-derived growth factor receptor signaling pathway);GO:0051898(negative regulation of protein kinase B signaling);GO:0030336(negative regulation of cell migration);GO:0051019(mitogen-activated protein kinase binding);GO:0001772(immunological synapse);GO:0050918(positive chemotaxis);GO:0043407(negative regulation of MAP kinase activity);GO:0005161(platelet-derived growth factor receptor binding);GO:0051894(positive regulation of focal adhesion assembly);GO:0050860(negative regulation of T cell receptor signaling pathway);GO:0042059(negative regulation of epidermal growth factor receptor signaling pathway);GO:0060242(contact inhibition);GO:0060242(contact inhibition)","04520(Adherens junction);04520(Adherens junction)","K05698","EC:3.1.3.48","protein tyrosine phosphatase, receptor type J [Source:HGNC Symbol;Acc:HGNC:9673]",{"v":20.8863503630884,"d":"20.89"},{"v":6.33347053496831,"d":"6.33"},{"v":3.29777335313567,"d":"3.30"},{"v":1.72149224973255,"d":"1.72"},{"v":0.0295105655079373,"d":"0.03"},{"v":0.42359540416002,"d":"0.42"},"up","yes"]
["ENSG00000130699","TAF4","ENST00000252996;ENST00000486599;ENST00000609041;ENST00000609045;ENST00000608458;ENST00000608887;ENST00000474089;ENST00000436129","GO:0006352(DNA-templated transcription, initiation);GO:0005669(transcription factor TFIID complex);GO:0005634(nucleus);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0046982(protein heterodimerization activity);GO:0045893(positive regulation of transcription, DNA-templated);GO:0006367(transcription initiation from RNA polymerase II promoter);GO:0005515(protein binding);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0016032(viral process);GO:0003713(transcription coactivator activity);GO:0006366(transcription from RNA polymerase II promoter);GO:0006368(transcription elongation from RNA polymerase II promoter);GO:0001075(transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly);GO:0017162(aryl hydrocarbon receptor binding);GO:0001541(ovarian follicle development);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0051123(RNA polymerase II transcriptional preinitiation complex assembly);GO:1901796(regulation of signal transduction by p53 class mediator);GO:0000790(nuclear chromatin);GO:0033276(transcription factor TFTC complex);GO:0043234(protein complex);GO:0071339(MLL1 complex);GO:0071339(MLL1 complex)","03022(Basal transcription factors);05016(Huntington's disease);05168(Herpes simplex infection);05168(Herpes simplex infection)","K03129","NA","TATA-box binding protein associated factor 4 [Source:HGNC Symbol;Acc:HGNC:11537]",{"v":1.75692921839315,"d":"1.76"},{"v":0.526997128670473,"d":"0.53"},{"v":3.33384969824332,"d":"3.33"},{"v":1.73718906398633,"d":"1.74"},{"v":0.0295785017155949,"d":"0.03"},{"v":0.42359540416002,"d":"0.42"},"up","yes"]
["MSTRG.4628","ITPK1","ENST00000555495;ENST00000267615;ENST00000554999;ENST00000354313;ENST00000553655;ENST00000556603;ENST00000555553;ENST00000556954;ENST00000553695;ENST00000556185","GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0016853(isomerase activity);GO:0016740(transferase activity);GO:0000287(magnesium ion binding);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0016787(hydrolase activity);GO:0005622(intracellular);GO:0016311(dephosphorylation);GO:0047325(inositol tetrakisphosphate 1-kinase activity);GO:0052725(inositol-1,3,4-trisphosphate 6-kinase activity);GO:0052726(inositol-1,3,4-trisphosphate 5-kinase activity);GO:0021915(neural tube development);GO:0032957(inositol trisphosphate metabolic process);GO:0016324(apical plasma membrane);GO:0005829(cytosol);GO:0007165(signal transduction);GO:0043647(inositol phosphate metabolic process);GO:0003824(catalytic activity);GO:0007596(blood coagulation);GO:0052659(inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity);GO:0052825(inositol-1,3,4,5,6-pentakisphosphate 1-phosphatase activity);GO:0052830(inositol-1,3,4,6-tetrakisphosphate 6-phosphatase activity);GO:0052831(inositol-1,3,4,6-tetrakisphosphate 1-phosphatase activity);GO:0052835(inositol-3,4,6-trisphosphate 1-kinase activity);GO:0052835(inositol-3,4,6-trisphosphate 1-kinase activity)","00562(Inositol phosphate metabolism);04070(Phosphatidylinositol signaling system);04070(Phosphatidylinositol signaling system)","K00913","EC:2.7.1.159;EC:2.7.1.134","inositol-tetrakisphosphate 1-kinase [Source:HGNC Symbol;Acc:HGNC:6177]",{"v":19.6439539823087,"d":"19.64"},{"v":5.95419494220846,"d":"5.95"},{"v":3.29917884331523,"d":"3.30"},{"v":1.72210698626008,"d":"1.72"},{"v":0.0295820091943319,"d":"0.03"},{"v":0.42359540416002,"d":"0.42"},"up","yes"]
["ENSG00000011451","WIZ","ENST00000263381;ENST00000595214;ENST00000600632;ENST00000389282;ENST00000599910;ENST00000545156;ENST00000599686","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0005654(nucleoplasm);GO:0030496(midbody);GO:0005515(protein binding);GO:0070062(extracellular exosome);GO:0050821(protein stabilization);GO:0010571(positive regulation of nuclear cell cycle DNA replication);GO:0070208(protein heterotrimerization);GO:0070984(SET domain binding);GO:0070984(SET domain binding)","NA","NA","NA","widely interspaced zinc finger motifs [Source:HGNC Symbol;Acc:HGNC:30917]",{"v":1.81890256660389,"d":"1.82"},{"v":0.546194335342122,"d":"0.55"},{"v":3.33013810087316,"d":"3.33"},{"v":1.73558200712044,"d":"1.74"},{"v":0.029693705872543,"d":"0.03"},{"v":0.423800037323686,"d":"0.42"},"up","yes"]
["ENSG00000163625","WDFY3","ENST00000295888;ENST00000514711;ENST00000509825;ENST00000505923;ENST00000514071;ENST00000504990;ENST00000425179;ENST00000502713;ENST00000512267;ENST00000509172;ENST00000426414","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0046872(metal ion binding);GO:0005730(nucleolus);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0006914(autophagy);GO:0003831(beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity);GO:0097635(extrinsic component of autophagosome membrane);GO:0005776(autophagosome);GO:0031965(nuclear membrane);GO:0005635(nuclear envelope);GO:0016605(PML body);GO:0016234(inclusion body);GO:0034274(Atg12-Atg5-Atg16 complex);GO:0005545(1-phosphatidylinositol binding);GO:0035973(aggrephagy);GO:0019898(extrinsic component of membrane);GO:0019898(extrinsic component of membrane)","NA","NA","NA","WD repeat and FYVE domain containing 3 [Source:HGNC Symbol;Acc:HGNC:20751]",{"v":7.65293947887992,"d":"7.65"},{"v":2.32282938739915,"d":"2.32"},{"v":3.29466275930358,"d":"3.29"},{"v":1.72013079895707,"d":"1.72"},{"v":0.0297713212635152,"d":"0.03"},{"v":0.423800037323686,"d":"0.42"},"up","yes"]
["MSTRG.8619","CRIM1","ENST00000280527;ENST00000481321","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005576(extracellular region);GO:0004867(serine-type endopeptidase inhibitor activity);GO:0010951(negative regulation of endopeptidase activity);GO:0005886(plasma membrane);GO:0043086(negative regulation of catalytic activity);GO:0005520(insulin-like growth factor binding);GO:0001558(regulation of cell growth);GO:0070062(extracellular exosome);GO:0004857(enzyme inhibitor activity);GO:0007399(nervous system development);GO:0005010(insulin-like growth factor-activated receptor activity);GO:0048009(insulin-like growth factor receptor signaling pathway);GO:0030165(PDZ domain binding);GO:0030165(PDZ domain binding)","NA","NA","NA","cysteine rich transmembrane BMP regulator 1 [Source:HGNC Symbol;Acc:HGNC:2359]",{"v":0.948088231395675,"d":"0.95"},{"v":0.280528633529907,"d":"0.28"},{"v":3.37964869919277,"d":"3.38"},{"v":1.75687329198897,"d":"1.76"},{"v":0.0297754105063098,"d":"0.03"},{"v":0.423800037323686,"d":"0.42"},"up","yes"]
["ENSG00000121297","TSHZ3","ENST00000240587;ENST00000560707","GO:0005634(nucleus);GO:0003676(nucleic acid binding);GO:0046872(metal ion binding);GO:0005654(nucleoplasm);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0042995(cell projection);GO:0005515(protein binding);GO:0045892(negative regulation of transcription, DNA-templated);GO:0007275(multicellular organism development);GO:0003682(chromatin binding);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0010468(regulation of gene expression);GO:0030426(growth cone);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0060291(long-term synaptic potentiation);GO:0001078(transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0002087(regulation of respiratory gaseous exchange by neurological system process);GO:0051968(positive regulation of synaptic transmission, glutamatergic);GO:0051968(positive regulation of synaptic transmission, glutamatergic)","NA","NA","NA","teashirt zinc finger homeobox 3 [Source:HGNC Symbol;Acc:HGNC:30700]",{"v":3.21136745384219,"d":"3.21"},{"v":0.970740692453155,"d":"0.97"},{"v":3.30816198270906,"d":"3.31"},{"v":1.72602987717233,"d":"1.73"},{"v":0.0297925544506145,"d":"0.03"},{"v":0.423800037323686,"d":"0.42"},"up","yes"]
["ENSG00000173402","DAG1","ENST00000308775;ENST00000479935;ENST00000461987;ENST00000428779;ENST00000421560;ENST00000435508;ENST00000538711;ENST00000545947","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005509(calcium ion binding);GO:0003779(actin binding);GO:0005886(plasma membrane);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0005615(extracellular space);GO:0030054(cell junction);GO:0045202(synapse);GO:0045211(postsynaptic membrane);GO:0005654(nucleoplasm);GO:0005925(focal adhesion);GO:0005604(basement membrane);GO:0007016(cytoskeletal anchoring at plasma membrane);GO:0046718(viral entry into host cell);GO:0005829(cytosol);GO:0030027(lamellipodium);GO:0030175(filopodium);GO:0070062(extracellular exosome);GO:0042169(SH2 domain binding);GO:0042383(sarcolemma);GO:0016032(viral process);GO:0010717(regulation of epithelial to mesenchymal transition);GO:0016010(dystrophin-associated glycoprotein complex);GO:0005788(endoplasmic reticulum lumen);GO:0006607(NLS-bearing protein import into nucleus);GO:0015631(tubulin binding);GO:0030198(extracellular matrix organization);GO:0005796(Golgi lumen);GO:0006509(membrane protein ectodomain proteolysis);GO:0051898(negative regulation of protein kinase B signaling);GO:0008307(structural constituent of muscle);GO:0017166(vinculin binding);GO:0001618(virus receptor activity);GO:0030336(negative regulation of cell migration);GO:0006493(protein O-linked glycosylation);GO:0070938(contractile ring);GO:0010470(regulation of gastrulation);GO:0034453(microtubule anchoring);GO:1904261(positive regulation of basement membrane assembly involved in embryonic body morphogenesis);GO:0043409(negative regulation of MAPK cascade);GO:0043237(laminin-1 binding);GO:0019048(modulation by virus of host morphology or physiology);GO:0016476(regulation of embryonic cell shape);GO:0051393(alpha-actinin binding);GO:0002162(dystroglycan binding);GO:0043236(laminin binding);GO:0001954(positive regulation of cell-matrix adhesion);GO:0002011(morphogenesis of an epithelial sheet);GO:0007568(aging);GO:0014037(Schwann cell differentiation);GO:0014044(Schwann cell development);GO:0014894(response to denervation involved in regulation of muscle adaptation);GO:0016340(calcium-dependent cell-matrix adhesion);GO:0021675(nerve development);GO:0021682(nerve maturation);GO:0022011(myelination in peripheral nervous system);GO:0031103(axon regeneration);GO:0031643(positive regulation of myelination);GO:0043403(skeletal muscle tissue regeneration);GO:0043434(response to peptide hormone);GO:0045860(positive regulation of protein kinase activity);GO:0048714(positive regulation of oligodendrocyte differentiation);GO:0060055(angiogenesis involved in wound healing);GO:0060441(epithelial tube branching involved in lung morphogenesis);GO:0060445(branching involved in salivary gland morphogenesis);GO:0071260(cellular response to mechanical stimulus);GO:0071397(cellular response to cholesterol);GO:0071679(commissural neuron axon guidance);GO:0071711(basement membrane organization);GO:0005911(cell-cell junction);GO:0005913(cell-cell adherens junction);GO:0009897(external side of plasma membrane);GO:0016011(dystroglycan complex);GO:0016323(basolateral plasma membrane);GO:0033268(node of Ranvier);GO:0034399(nuclear periphery);GO:0043034(costamere);GO:0044853(plasma membrane raft);GO:0045121(membrane raft);GO:0045121(membrane raft)","04512(ECM-receptor interaction);05410(Hypertrophic cardiomyopathy (HCM));05412(Arrhythmogenic right ventricular cardiomyopathy (ARVC));05414(Dilated cardiomyopathy (DCM));05416(Viral myocarditis);05416(Viral myocarditis)","K06265","NA","dystroglycan 1 [Source:HGNC Symbol;Acc:HGNC:2666]",{"v":1.55825536718186,"d":"1.56"},{"v":0.468141188935433,"d":"0.47"},{"v":3.32860129382202,"d":"3.33"},{"v":1.73491607207796,"d":"1.73"},{"v":0.0298254644499377,"d":"0.03"},{"v":0.423800037323686,"d":"0.42"},"up","yes"]
["MSTRG.10547","RRP7A","ENST00000323013;ENST00000416699;ENST00000483303","GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0005515(protein binding);GO:0000028(ribosomal small subunit assembly);GO:0005654(nucleoplasm);GO:0006364(rRNA processing);GO:0032545(CURI complex);GO:0034456(UTP-C complex);GO:0001825(blastocyst formation);GO:0005737(cytoplasm);GO:0005737(cytoplasm)","03008(Ribosome biogenesis in eukaryotes);03008(Ribosome biogenesis in eukaryotes)","K14545","NA","ribosomal RNA processing 7 homolog A [Source:HGNC Symbol;Acc:HGNC:24286]",{"v":2.27697837751102,"d":"2.28"},{"v":5.18958698456639,"d":"5.19"},{"v":0.438759073560701,"d":"0.44"},{"v":-1.1884991341524,"d":"-1.19"},{"v":0.0298701974373618,"d":"0.03"},{"v":0.423800037323686,"d":"0.42"},"down","yes"]
["MSTRG.10099","IL17RA","ENST00000612619;ENST00000319363;ENST00000459971;ENST00000477874","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0019221(cytokine-mediated signaling pathway);GO:0005887(integral component of plasma membrane);GO:0007166(cell surface receptor signaling pathway);GO:0032747(positive regulation of interleukin-23 production);GO:0072537(fibroblast activation);GO:0097398(cellular response to interleukin-17);GO:0030368(interleukin-17 receptor activity);GO:0005102(receptor binding);GO:0050729(positive regulation of inflammatory response);GO:0050832(defense response to fungus);GO:0071345(cellular response to cytokine stimulus);GO:0071621(granulocyte chemotaxis);GO:1900017(positive regulation of cytokine production involved in inflammatory response);GO:2000664(positive regulation of interleukin-5 secretion);GO:2000667(positive regulation of interleukin-13 secretion);GO:2000667(positive regulation of interleukin-13 secretion)","04060(Cytokine-cytokine receptor interaction);04657(IL-17 signaling pathway);04657(IL-17 signaling pathway)","K05164","NA","interleukin 17 receptor A [Source:HGNC Symbol;Acc:HGNC:5985]",{"v":41.6238726186366,"d":"41.62"},{"v":12.6611102701417,"d":"12.66"},{"v":3.28753732733826,"d":"3.29"},{"v":1.71700727513804,"d":"1.72"},{"v":0.0298841285085102,"d":"0.03"},{"v":0.423800037323686,"d":"0.42"},"up","yes"]
["MSTRG.1078","MEF2D","ENST00000348159;MSTRG.1078.1;ENST00000464356;ENST00000489057;ENST00000493077;ENST00000368240","GO:0005634(nucleus);GO:0043231(intracellular membrane-bounded organelle);GO:0005654(nucleoplasm);GO:0046983(protein dimerization activity);GO:0006366(transcription from RNA polymerase II promoter);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0006915(apoptotic process);GO:0007275(multicellular organism development);GO:0007399(nervous system development);GO:0030154(cell differentiation);GO:0000977(RNA polymerase II regulatory region sequence-specific DNA binding);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0005515(protein binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0000981(RNA polymerase II transcription factor activity, sequence-specific DNA binding);GO:0007517(muscle organ development);GO:0042826(histone deacetylase binding);GO:0033613(activating transcription factor binding);GO:0007512(adult heart development);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:0001077(transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0019899(enzyme binding);GO:0042803(protein homodimerization activity);GO:0046982(protein heterodimerization activity);GO:0001649(osteoblast differentiation);GO:0001958(endochondral ossification);GO:0002062(chondrocyte differentiation);GO:0035914(skeletal muscle cell differentiation);GO:0045893(positive regulation of transcription, DNA-templated);GO:0005737(cytoplasm);GO:0005737(cytoplasm)","04371(Apelin signaling pathway);04022(cGMP - PKG signaling pathway);04022(cGMP - PKG signaling pathway)","K09262","NA","myocyte enhancer factor 2D [Source:HGNC Symbol;Acc:HGNC:6997]",{"v":10.4879294264216,"d":"10.49"},{"v":3.18432643032846,"d":"3.18"},{"v":3.29361001640142,"d":"3.29"},{"v":1.71966974124774,"d":"1.72"},{"v":0.0299217068729828,"d":"0.03"},{"v":0.423800037323686,"d":"0.42"},"up","yes"]
["MSTRG.14480","POLR2K","ENST00000353107;ENST00000522439;ENST00000519765","GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0003677(DNA binding);GO:0006351(transcription, DNA-templated);GO:0003899(DNA-directed 5'-3' RNA polymerase activity);GO:0005666(DNA-directed RNA polymerase III complex);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0006366(transcription from RNA polymerase II promoter);GO:0045815(positive regulation of gene expression, epigenetic);GO:0006368(transcription elongation from RNA polymerase II promoter);GO:0006370(7-methylguanosine mRNA capping);GO:0050434(positive regulation of viral transcription);GO:0006367(transcription initiation from RNA polymerase II promoter);GO:0042795(snRNA transcription from RNA polymerase II promoter);GO:0001056(RNA polymerase III activity);GO:0032481(positive regulation of type I interferon production);GO:0000398(mRNA splicing, via spliceosome);GO:0001054(RNA polymerase I activity);GO:0006361(transcription initiation from RNA polymerase I promoter);GO:0006362(transcription elongation from RNA polymerase I promoter);GO:0006363(termination of RNA polymerase I transcription);GO:0005736(DNA-directed RNA polymerase I complex);GO:0008270(zinc ion binding);GO:0060964(regulation of gene silencing by miRNA);GO:0006283(transcription-coupled nucleotide-excision repair);GO:0008543(fibroblast growth factor receptor signaling pathway);GO:0016070(RNA metabolic process);GO:0035019(somatic stem cell population maintenance);GO:0005665(DNA-directed RNA polymerase II, core complex);GO:0006383(transcription from RNA polymerase III promoter);GO:0006356(regulation of transcription from RNA polymerase I promoter);GO:0001055(RNA polymerase II activity);GO:0001055(RNA polymerase II activity)","00230(Purine metabolism);00240(Pyrimidine metabolism);03020(RNA polymerase);04623(Cytosolic DNA-sensing pathway);05016(Huntington's disease);05169(Epstein-Barr virus infection);05169(Epstein-Barr virus infection)","K03009","NA","RNA polymerase II subunit K [Source:HGNC Symbol;Acc:HGNC:9198]",{"v":6.59211964991233,"d":"6.59"},{"v":14.9935830233781,"d":"14.99"},{"v":0.439662730358304,"d":"0.44"},{"v":-1.18553085254863,"d":"-1.19"},{"v":0.0299247421515046,"d":"0.03"},{"v":0.423800037323686,"d":"0.42"},"down","yes"]
["MSTRG.9873","RPS21","ENST00000343986;ENST00000450116;ENST00000492356;ENST00000370592;ENST00000370562","GO:0003723(RNA binding);GO:0006412(translation);GO:0030529(intracellular ribonucleoprotein complex);GO:0005622(intracellular);GO:0003735(structural constituent of ribosome);GO:0005840(ribosome);GO:0022627(cytosolic small ribosomal subunit);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0047485(protein N-terminus binding);GO:0006413(translational initiation);GO:0006364(rRNA processing);GO:0000184(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay);GO:0019083(viral transcription);GO:0006614(SRP-dependent cotranslational protein targeting to membrane);GO:0000447(endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA));GO:0000461(endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA));GO:0015935(small ribosomal subunit);GO:0005515(protein binding);GO:0005515(protein binding)","03010(Ribosome);03010(Ribosome)","K02971","NA","ribosomal protein S21 [Source:HGNC Symbol;Acc:HGNC:10409]",{"v":67.021670402737,"d":"67.02"},{"v":151.580519534702,"d":"151.58"},{"v":0.442152267378879,"d":"0.44"},{"v":-1.17738480770866,"d":"-1.18"},{"v":0.0300831102166435,"d":"0.03"},{"v":0.425177689157463,"d":"0.43"},"down","yes"]
["MSTRG.1762","DDIT4","ENST00000307365;ENST00000473155;ENST00000471240","GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0071889(14-3-3 protein binding);GO:0001666(response to hypoxia);GO:0009968(negative regulation of signal transduction);GO:0032007(negative regulation of TOR signaling);GO:0042771(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator);GO:0043241(protein complex disassembly);GO:0045820(negative regulation of glycolytic process);GO:0071549(cellular response to dexamethasone stimulus);GO:0072593(reactive oxygen species metabolic process);GO:0005739(mitochondrion);GO:0006915(apoptotic process);GO:0051607(defense response to virus);GO:0008283(cell proliferation);GO:0007420(brain development);GO:0030182(neuron differentiation);GO:0005622(intracellular);GO:0001764(neuron migration);GO:0048011(neurotrophin TRK receptor signaling pathway);GO:1902532(negative regulation of intracellular signal transduction);GO:0033137(negative regulation of peptidyl-serine phosphorylation);GO:0010801(negative regulation of peptidyl-threonine phosphorylation);GO:1901216(positive regulation of neuron death);GO:1901216(positive regulation of neuron death)","04151(PI3K-Akt signaling pathway);04150(mTOR signaling pathway);04140(Autophagy - animal);05206(MicroRNAs in cancer);05206(MicroRNAs in cancer)","K08270","NA","DNA damage inducible transcript 4 [Source:HGNC Symbol;Acc:HGNC:24944]",{"v":6.59715273760933,"d":"6.60"},{"v":14.9738102653061,"d":"14.97"},{"v":0.440579426393211,"d":"0.44"},{"v":-1.18252596737805,"d":"-1.18"},{"v":0.0300952433038349,"d":"0.03"},{"v":0.425177689157463,"d":"0.43"},"down","yes"]
["ENSG00000172985","SH3RF3","ENST00000309415","GO:0046872(metal ion binding);GO:0005515(protein binding)","NA","NA","NA","SH3 domain containing ring finger 3 [Source:HGNC Symbol;Acc:HGNC:24699]",{"v":0.701906,"d":"0.70"},{"v":0.205991,"d":"0.21"},{"v":3.40745954920361,"d":"3.41"},{"v":1.76869653054193,"d":"1.77"},{"v":0.0301454005114518,"d":"0.03"},{"v":0.425286960367398,"d":"0.43"},"up","yes"]
["ENSG00000177728","TMEM94","ENST00000581085;ENST00000582843;ENST00000578624;ENST00000582186;ENST00000580849;ENST00000577194;ENST00000581834;ENST00000583071;ENST00000314256;ENST00000581453;ENST00000578853;ENST00000583296;ENST00000579898;ENST00000577247;ENST00000580441;ENST00000581723;ENST00000585105;ENST00000583795;ENST00000580918;ENST00000579707;ENST00000579241","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016021(integral component of membrane)","NA","NA","NA","transmembrane protein 94 [Source:HGNC Symbol;Acc:HGNC:28983]",{"v":3.25349748475265,"d":"3.25"},{"v":0.981560863451547,"d":"0.98"},{"v":3.31461614444579,"d":"3.31"},{"v":1.72884180591271,"d":"1.73"},{"v":0.0301762210748933,"d":"0.03"},{"v":0.425286960367398,"d":"0.43"},"up","yes"]
["ENSG00000196417","ZNF765","ENST00000396408;ENST00000504235;ENST00000504146;ENST00000505866;ENST00000507045;ENST00000594030","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0005622(intracellular);GO:0005515(protein binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding)","NA","NA","NA","zinc finger protein 765 [Source:HGNC Symbol;Acc:HGNC:25092]",{"v":0.23439052227803,"d":"0.23"},{"v":0.539949778434867,"d":"0.54"},{"v":0.434096895006512,"d":"0.43"},{"v":-1.20391099151962,"d":"-1.20"},{"v":0.030265529364245,"d":"0.03"},{"v":0.425682929338254,"d":"0.43"},"down","yes"]
["ENSG00000124496","TRERF1","ENST00000541110;ENST00000340840;ENST00000372917;ENST00000354325;ENST00000372922","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0005730(nucleolus);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0006694(steroid biosynthetic process);GO:0007275(multicellular organism development);GO:0030374(ligand-dependent nuclear receptor transcription coactivator activity);GO:0045893(positive regulation of transcription, DNA-templated);GO:0005667(transcription factor complex);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0008134(transcription factor binding);GO:0042592(homeostatic process);GO:0046885(regulation of hormone biosynthetic process);GO:0008301(DNA binding, bending);GO:0001104(RNA polymerase II transcription cofactor activity);GO:0044212(transcription regulatory region DNA binding);GO:0006707(cholesterol catabolic process);GO:0000118(histone deacetylase complex);GO:0000118(histone deacetylase complex)","NA","NA","NA","transcriptional regulating factor 1 [Source:HGNC Symbol;Acc:HGNC:18273]",{"v":3.66322816864977,"d":"3.66"},{"v":1.11042793947232,"d":"1.11"},{"v":3.29893371594248,"d":"3.30"},{"v":1.72199979074256,"d":"1.72"},{"v":0.0303044902333706,"d":"0.03"},{"v":0.425682929338254,"d":"0.43"},"up","yes"]
["MSTRG.12593","MAML1","ENST00000292599;ENST00000507385;ENST00000511027","GO:0005634(nucleus);GO:0016607(nuclear speck);GO:0043231(intracellular membrane-bounded organelle);GO:0005654(nucleoplasm);GO:0003713(transcription coactivator activity);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0007219(Notch signaling pathway);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0005515(protein binding);GO:0019901(protein kinase binding);GO:0006367(transcription initiation from RNA polymerase II promoter);GO:0006468(protein phosphorylation);GO:0042605(peptide antigen binding);GO:0010831(positive regulation of myotube differentiation);GO:0002193(MAML1-RBP-Jkappa- ICN1 complex);GO:0007221(positive regulation of transcription of Notch receptor target);GO:0003162(atrioventricular node development);GO:0045445(myoblast differentiation);GO:0051149(positive regulation of muscle cell differentiation);GO:0060928(atrioventricular node cell development);GO:0060928(atrioventricular node cell development)","04330(Notch signaling pathway);04658(Th1 and Th2 cell differentiation);05165(Human papillomavirus infection);05165(Human papillomavirus infection)","K06061","NA","mastermind like transcriptional coactivator 1 [Source:HGNC Symbol;Acc:HGNC:13632]",{"v":13.0485155784248,"d":"13.05"},{"v":3.9724823781555,"d":"3.97"},{"v":3.28472585559548,"d":"3.28"},{"v":1.71577296772356,"d":"1.72"},{"v":0.0303142842127561,"d":"0.03"},{"v":0.425682929338254,"d":"0.43"},"up","yes"]
["ENSG00000132003","ZSWIM4","ENST00000590508;ENST00000254323;ENST00000592227","GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0046872(metal ion binding)","NA","NA","NA","zinc finger SWIM-type containing 4 [Source:HGNC Symbol;Acc:HGNC:25704]",{"v":0.936935723742839,"d":"0.94"},{"v":0.274570901124549,"d":"0.27"},{"v":3.41236350940857,"d":"3.41"},{"v":1.77077134105447,"d":"1.77"},{"v":0.0304005499141575,"d":"0.03"},{"v":0.426009697297422,"d":"0.43"},"up","yes"]
["MSTRG.10823","RPSA","ENST00000443003;ENST00000458478;ENST00000444512;ENST00000478027;ENST00000495394;ENST00000301821;ENST00000475346;ENST00000487876;ENST00000477325","GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0006412(translation);GO:0007155(cell adhesion);GO:0030529(intracellular ribonucleoprotein complex);GO:0005622(intracellular);GO:0003735(structural constituent of ribosome);GO:0005840(ribosome);GO:0005886(plasma membrane);GO:0015935(small ribosomal subunit);GO:0005515(protein binding);GO:0005055(laminin receptor activity);GO:0043236(laminin binding);GO:0000028(ribosomal small subunit assembly);GO:0022627(cytosolic small ribosomal subunit);GO:0043022(ribosome binding);GO:0046718(viral entry into host cell);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0016032(viral process);GO:0006413(translational initiation);GO:0006364(rRNA processing);GO:0001618(virus receptor activity);GO:0030686(90S preribosome);GO:0000184(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay);GO:0019083(viral transcription);GO:0006614(SRP-dependent cotranslational protein targeting to membrane);GO:0000447(endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA));GO:0000461(endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA));GO:0006407(rRNA export from nucleus);GO:0016337(single organismal cell-cell adhesion);GO:0030855(epithelial cell differentiation);GO:0005604(basement membrane);GO:0031012(extracellular matrix);GO:0043025(neuronal cell body);GO:0043025(neuronal cell body)","03010(Ribosome);03010(Ribosome)","K02998","NA","ribosomal protein SA [Source:HGNC Symbol;Acc:HGNC:6502]",{"v":115.673679427083,"d":"115.67"},{"v":260.781653896341,"d":"260.78"},{"v":0.443565249697598,"d":"0.44"},{"v":-1.172781750246,"d":"-1.17"},{"v":0.0304598566289083,"d":"0.03"},{"v":0.426009697297422,"d":"0.43"},"down","yes"]
["MSTRG.131","H6PD","ENST00000377403;ENST00000602477","GO:0016491(oxidoreductase activity);GO:0050661(NADP binding);GO:0055114(oxidation-reduction process);GO:0016787(hydrolase activity);GO:0005975(carbohydrate metabolic process);GO:0005783(endoplasmic reticulum);GO:0003824(catalytic activity);GO:0008152(metabolic process);GO:0005788(endoplasmic reticulum lumen);GO:0006006(glucose metabolic process);GO:0017057(6-phosphogluconolactonase activity);GO:0006098(pentose-phosphate shunt);GO:0004345(glucose-6-phosphate dehydrogenase activity);GO:0047936(glucose 1-dehydrogenase [NAD(P)] activity);GO:0030246(carbohydrate binding);GO:0006739(NADP metabolic process);GO:0097305(response to alcohol);GO:0005737(cytoplasm);GO:0005739(mitochondrion);GO:0043231(intracellular membrane-bounded organelle);GO:0043231(intracellular membrane-bounded organelle)","00030(Pentose phosphate pathway);00030(Pentose phosphate pathway)","K13937","EC:1.1.1.47;EC:3.1.1.31","hexose-6-phosphate dehydrogenase/glucose 1-dehydrogenase [Source:HGNC Symbol;Acc:HGNC:4795]",{"v":6.65801963802167,"d":"6.66"},{"v":2.02853687866109,"d":"2.03"},{"v":3.28217825766925,"d":"3.28"},{"v":1.71465359487591,"d":"1.71"},{"v":0.0304829876762328,"d":"0.03"},{"v":0.426009697297422,"d":"0.43"},"up","yes"]
["MSTRG.5784","ATXN2L","ENST00000325215;ENST00000566946;ENST00000336783;ENST00000561732;ENST00000562583;ENST00000562867;ENST00000565845;ENST00000564304;ENST00000564656;ENST00000395547;ENST00000570200;ENST00000564284;ENST00000563314;ENST00000382686;ENST00000564035;ENST00000561539;ENST00000570284;ENST00000340394;ENST00000566080;MSTRG.5784.10;ENST00000562686;ENST00000569318","GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016607(nuclear speck);GO:0016020(membrane);GO:0005829(cytosol);GO:0005515(protein binding);GO:0045296(cadherin binding);GO:0010494(cytoplasmic stress granule);GO:0034063(stress granule assembly);GO:0010603(regulation of cytoplasmic mRNA processing body assembly);GO:0016021(integral component of membrane);GO:0016021(integral component of membrane)","NA","NA","NA","ataxin 2 like [Source:HGNC Symbol;Acc:HGNC:31326]",{"v":9.84233896880762,"d":"9.84"},{"v":2.99448267547634,"d":"2.99"},{"v":3.28682448204245,"d":"3.29"},{"v":1.71669441788831,"d":"1.72"},{"v":0.0305146488820164,"d":"0.03"},{"v":0.426009697297422,"d":"0.43"},"up","yes"]
["ENSG00000123360","PDE1B","ENST00000243052;ENST00000538346;ENST00000548855;ENST00000611899;ENST00000552774","GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0005634(nucleus);GO:0005829(cytosol);GO:0016787(hydrolase activity);GO:0007165(signal transduction);GO:0005515(protein binding);GO:0008081(phosphoric diester hydrolase activity);GO:0004112(cyclic-nucleotide phosphodiesterase activity);GO:0004114(3',5'-cyclic-nucleotide phosphodiesterase activity);GO:0004115(3',5'-cyclic-AMP phosphodiesterase activity);GO:0048101(calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity);GO:0001505(regulation of neurotransmitter levels);GO:0001975(response to amphetamine);GO:0006198(cAMP catabolic process);GO:0007626(locomotory behavior);GO:0008542(visual learning);GO:0042053(regulation of dopamine metabolic process);GO:0042428(serotonin metabolic process);GO:0046069(cGMP catabolic process);GO:0043025(neuronal cell body);GO:0005516(calmodulin binding);GO:0006915(apoptotic process);GO:0047555(3',5'-cyclic-GMP phosphodiesterase activity);GO:0036006(cellular response to macrophage colony-stimulating factor stimulus);GO:0030224(monocyte differentiation);GO:0097011(cellular response to granulocyte macrophage colony-stimulating factor stimulus);GO:0004117(calmodulin-dependent cyclic-nucleotide phosphodiesterase activity);GO:0004117(calmodulin-dependent cyclic-nucleotide phosphodiesterase activity)","00230(Purine metabolism);04020(Calcium signaling pathway);04924(Renin secretion);04740(Olfactory transduction);04742(Taste transduction);05032(Morphine addiction);05032(Morphine addiction)","K13755","EC:3.1.4.17","phosphodiesterase 1B [Source:HGNC Symbol;Acc:HGNC:8775]",{"v":0.374903474927803,"d":"0.37"},{"v":0.107148402467839,"d":"0.11"},{"v":3.49891800804339,"d":"3.50"},{"v":1.80690885755429,"d":"1.81"},{"v":0.030579808817145,"d":"0.03"},{"v":0.426009697297422,"d":"0.43"},"up","yes"]
["MSTRG.9567","FASTKD5;UBOX5","ENST00000380266;ENST00000217173;ENST00000449731;ENST00000348031","GO:0003723(RNA binding);GO:0006397(mRNA processing);GO:0004672(protein kinase activity);GO:0006468(protein phosphorylation);GO:0005739(mitochondrion);GO:0005515(protein binding);GO:0019843(rRNA binding);GO:0045333(cellular respiration);GO:0042645(mitochondrial nucleoid);GO:0035770(ribonucleoprotein granule);GO:0000963(mitochondrial RNA processing);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0005654(nucleoplasm);GO:0016740(transferase activity);GO:0016567(protein ubiquitination);GO:0005925(focal adhesion);GO:0004842(ubiquitin-protein transferase activity);GO:0031625(ubiquitin protein ligase binding);GO:0016604(nuclear body);GO:0000209(protein polyubiquitination);GO:0034450(ubiquitin-ubiquitin ligase activity);GO:0061630(ubiquitin protein ligase activity);GO:0061630(ubiquitin protein ligase activity)","04120(Ubiquitin mediated proteolysis);04120(Ubiquitin mediated proteolysis)","K10600","NA","FAST kinase domains 5 [Source:HGNC Symbol;Acc:HGNC:25790];U-box domain containing 5 [Source:HGNC Symbol;Acc:HGNC:17777]",{"v":1.51353278582888,"d":"1.51"},{"v":3.42346409358289,"d":"3.42"},{"v":0.442105640501947,"d":"0.44"},{"v":-1.17753695418897,"d":"-1.18"},{"v":0.0306115903036549,"d":"0.03"},{"v":0.426009697297422,"d":"0.43"},"down","yes"]
["MSTRG.9651","ZNF341","ENST00000342427;ENST00000493497;ENST00000375200","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding)","NA","NA","NA","zinc finger protein 341 [Source:HGNC Symbol;Acc:HGNC:15992]",{"v":0.969782345611142,"d":"0.97"},{"v":0.287214147516951,"d":"0.29"},{"v":3.37651314879573,"d":"3.38"},{"v":1.75553417565789,"d":"1.76"},{"v":0.0306229284867482,"d":"0.03"},{"v":0.426009697297422,"d":"0.43"},"up","yes"]
["ENSG00000163554","SPTA1","ENST00000484520;ENST00000492934;ENST00000481212;ENST00000465741;ENST00000368147","GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0005509(calcium ion binding);GO:0003779(actin binding);GO:0051693(actin filament capping);GO:0043547(positive regulation of GTPase activity);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0005829(cytosol);GO:0005938(cell cortex);GO:0000165(MAPK cascade);GO:0008360(regulation of cell shape);GO:0015629(actin cytoskeleton);GO:0005200(structural constituent of cytoskeleton);GO:0007411(axon guidance);GO:0006888(ER to Golgi vesicle-mediated transport);GO:0005088(Ras guanyl-nucleotide exchange factor activity);GO:0008091(spectrin);GO:0046982(protein heterodimerization activity);GO:0051015(actin filament binding);GO:0002260(lymphocyte homeostasis);GO:0006779(porphyrin-containing compound biosynthetic process);GO:0007009(plasma membrane organization);GO:0007015(actin filament organization);GO:0030036(actin cytoskeleton organization);GO:0030097(hemopoiesis);GO:0032092(positive regulation of protein binding);GO:0042102(positive regulation of T cell proliferation);GO:0009898(cytoplasmic side of plasma membrane);GO:0014731(spectrin-associated cytoskeleton);GO:0016020(membrane);GO:0030424(axon);GO:0030863(cortical cytoskeleton);GO:0031235(intrinsic component of the cytoplasmic side of the plasma membrane);GO:0032437(cuticular plate);GO:0032437(cuticular plate)","04210(Apoptosis);04210(Apoptosis)","K06114","NA","spectrin alpha, erythrocytic 1 [Source:HGNC Symbol;Acc:HGNC:11272]",{"v":0.269787718703242,"d":"0.27"},{"v":0.0758005731670823,"d":"0.08"},{"v":3.55917781925694,"d":"3.56"},{"v":1.83154401280038,"d":"1.83"},{"v":0.0306876105514973,"d":"0.03"},{"v":0.426009697297422,"d":"0.43"},"up","yes"]
["ENSG00000126970","ZC4H2","ENST00000476032;ENST00000488831;ENST00000488608;ENST00000374839;ENST00000337990;ENST00000447788","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0046872(metal ion binding);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0007275(multicellular organism development);GO:0030054(cell junction);GO:0045202(synapse);GO:0045211(postsynaptic membrane);GO:0007399(nervous system development);GO:0007528(neuromuscular junction development);GO:0021522(spinal cord motor neuron differentiation);GO:0021522(spinal cord motor neuron differentiation)","NA","NA","NA","zinc finger C4H2-type containing [Source:HGNC Symbol;Acc:HGNC:24931]",{"v":0.520438071138604,"d":"0.52"},{"v":0.141991890585734,"d":"0.14"},{"v":3.66526615704413,"d":"3.67"},{"v":1.87391796493635,"d":"1.87"},{"v":0.0306876105514973,"d":"0.03"},{"v":0.426009697297422,"d":"0.43"},"up","yes"]
["MSTRG.9344","FAM126B","ENST00000418596;ENST00000452799;ENST00000498780;ENST00000485144;ENST00000494881;ENST00000485636;ENST00000446678;ENST00000474118;ENST00000453765;ENST00000286181;ENST00000490725","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0005622(intracellular);GO:0005622(intracellular)","NA","NA","NA","family with sequence similarity 126 member B [Source:HGNC Symbol;Acc:HGNC:28593]",{"v":11.7556099722873,"d":"11.76"},{"v":3.5906875039032,"d":"3.59"},{"v":3.27391619557774,"d":"3.27"},{"v":1.71101739274309,"d":"1.71"},{"v":0.0307355418003479,"d":"0.03"},{"v":0.426009697297422,"d":"0.43"},"up","yes"]
["MSTRG.7897","ADGRL1","ENST00000340736;ENST00000589616;ENST00000592164;ENST00000591528;ENST00000588677;ENST00000590223","GO:0005622(intracellular);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0004930(G-protein coupled receptor activity);GO:0007186(G-protein coupled receptor signaling pathway);GO:0030246(carbohydrate binding);GO:0005886(plasma membrane);GO:0042995(cell projection);GO:0005515(protein binding);GO:0004871(signal transducer activity);GO:0007165(signal transduction);GO:0004888(transmembrane signaling receptor activity);GO:0007166(cell surface receptor signaling pathway);GO:0030054(cell junction);GO:0045202(synapse);GO:0030424(axon);GO:0030426(growth cone);GO:0043005(neuron projection);GO:0042734(presynaptic membrane);GO:0090129(positive regulation of synapse maturation);GO:0035584(calcium-mediated signaling using intracellular calcium source);GO:0016524(latrotoxin receptor activity);GO:0050839(cell adhesion molecule binding);GO:0007157(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules);GO:0051965(positive regulation of synapse assembly);GO:0051965(positive regulation of synapse assembly)","NA","NA","NA","adhesion G protein-coupled receptor L1 [Source:HGNC Symbol;Acc:HGNC:20973]",{"v":1.08787444314834,"d":"1.09"},{"v":0.32583562130317,"d":"0.33"},{"v":3.33872164988413,"d":"3.34"},{"v":1.73929582054358,"d":"1.74"},{"v":0.0307637798969298,"d":"0.03"},{"v":0.426009697297422,"d":"0.43"},"up","yes"]
["MSTRG.6115","HP","ENST00000355906;ENST00000566821;ENST00000357763;ENST00000570083;ENST00000561927;ENST00000565807;ENST00000398131;ENST00000565574","GO:0010942(positive regulation of cell death);GO:0005576(extracellular region);GO:0005515(protein binding);GO:0005615(extracellular space);GO:0098869(cellular oxidant detoxification);GO:0002376(immune system process);GO:0006898(receptor-mediated endocytosis);GO:0042742(defense response to bacterium);GO:0030492(hemoglobin binding);GO:0070062(extracellular exosome);GO:0072562(blood microparticle);GO:0043312(neutrophil degranulation);GO:0006953(acute-phase response);GO:0035580(specific granule lumen);GO:1904724(tertiary granule lumen);GO:0006952(defense response);GO:0016209(antioxidant activity);GO:0042542(response to hydrogen peroxide);GO:0051354(negative regulation of oxidoreductase activity);GO:2000296(negative regulation of hydrogen peroxide catabolic process);GO:0031838(haptoglobin-hemoglobin complex);GO:0071682(endocytic vesicle lumen);GO:0006508(proteolysis);GO:0004252(serine-type endopeptidase activity);GO:0004252(serine-type endopeptidase activity)","NA","NA","NA","haptoglobin [Source:HGNC Symbol;Acc:HGNC:5141]",{"v":0.553353766327475,"d":"0.55"},{"v":1.28572233376503,"d":"1.29"},{"v":0.430383568672303,"d":"0.43"},{"v":-1.21630509563477,"d":"-1.22"},{"v":0.0307777607881286,"d":"0.03"},{"v":0.426009697297422,"d":"0.43"},"down","yes"]
["MSTRG.762","CYB561D1","ENST00000310611;ENST00000430195;ENST00000369868;ENST00000496961;ENST00000420578;ENST00000528785;ENST00000533024","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0046872(metal ion binding);GO:0055114(oxidation-reduction process);GO:0055114(oxidation-reduction process)","NA","NA","NA","cytochrome b561 family member D1 [Source:HGNC Symbol;Acc:HGNC:26804]",{"v":2.26907846414763,"d":"2.27"},{"v":0.682877492442882,"d":"0.68"},{"v":3.3228192307677,"d":"3.32"},{"v":1.73240780913925,"d":"1.73"},{"v":0.0309976750678624,"d":"0.03"},{"v":0.428118374434226,"d":"0.43"},"up","yes"]
["MSTRG.12184","COX7C","ENST00000511472;ENST00000247655;ENST00000515763;ENST00000510447;ENST00000505430;ENST00000509578","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005743(mitochondrial inner membrane);GO:0005739(mitochondrion);GO:1902600(hydrogen ion transmembrane transport);GO:0004129(cytochrome-c oxidase activity);GO:0006123(mitochondrial electron transport, cytochrome c to oxygen);GO:0006091(generation of precursor metabolites and energy);GO:0005751(mitochondrial respiratory chain complex IV);GO:0005751(mitochondrial respiratory chain complex IV)","00190(Oxidative phosphorylation);04260(Cardiac muscle contraction);05010(Alzheimer's disease);05012(Parkinson's disease);05016(Huntington's disease);04932(Non-alcoholic fatty liver disease (NAFLD));04932(Non-alcoholic fatty liver disease (NAFLD))","K02272","NA","cytochrome c oxidase subunit 7C [Source:HGNC Symbol;Acc:HGNC:2292]",{"v":9.6656386246864,"d":"9.67"},{"v":21.7818284560963,"d":"21.78"},{"v":0.443747807681461,"d":"0.44"},{"v":-1.17218810294301,"d":"-1.17"},{"v":0.0310585941567836,"d":"0.03"},{"v":0.428118374434226,"d":"0.43"},"down","yes"]
["MSTRG.6236","PIEZO1","ENST00000301015;ENST00000484567;ENST00000472168;ENST00000497793;ENST00000566414;MSTRG.6236.1;ENST00000521877;ENST00000490756;ENST00000474606;ENST00000419505;ENST00000491917","GO:0016021(integral component of membrane);GO:0034220(ion transmembrane transport);GO:0008381(mechanically-gated ion channel activity);GO:0006810(transport);GO:0016020(membrane);GO:0098655(cation transmembrane transport);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0006811(ion transport);GO:0005886(plasma membrane);GO:0042995(cell projection);GO:0033634(positive regulation of cell-cell adhesion mediated by integrin);GO:0033116(endoplasmic reticulum-Golgi intermediate compartment membrane);GO:0042391(regulation of membrane potential);GO:0005261(cation channel activity);GO:0031258(lamellipodium membrane);GO:0006812(cation transport);GO:0050982(detection of mechanical stimulus);GO:0033625(positive regulation of integrin activation);GO:0071260(cellular response to mechanical stimulus);GO:0071260(cellular response to mechanical stimulus)","NA","NA","NA","piezo type mechanosensitive ion channel component 1 [Source:HGNC Symbol;Acc:HGNC:28993]",{"v":8.93284068521419,"d":"8.93"},{"v":2.73054085297098,"d":"2.73"},{"v":3.27145469202366,"d":"3.27"},{"v":1.70993229024883,"d":"1.71"},{"v":0.0310841826457052,"d":"0.03"},{"v":0.428118374434226,"d":"0.43"},"up","yes"]
["MSTRG.8846","LINC01291","ENST00000377469;ENST00000435984;ENST00000418204","NA","NA","NA","NA","long intergenic non-protein coding RNA 1291 [Source:HGNC Symbol;Acc:HGNC:50358]",{"v":0.97383613098659,"d":"0.97"},{"v":0.287465822796935,"d":"0.29"},{"v":3.38765882326994,"d":"3.39"},{"v":1.76028858577946,"d":"1.76"},{"v":0.0310857209697342,"d":"0.03"},{"v":0.428118374434226,"d":"0.43"},"up","yes"]
["MSTRG.10469","AL031846.2","ENST00000624656","NA","NA","NA","NA",null,{"v":1.040571,"d":"1.04"},{"v":0.305224,"d":"0.31"},{"v":3.40920438759731,"d":"3.41"},{"v":1.76943509409033,"d":"1.77"},{"v":0.0311144327927742,"d":"0.03"},{"v":0.428118374434226,"d":"0.43"},"up","yes"]
["MSTRG.4876","AC087481.3","ENST00000602886","NA","NA","NA","NA",null,{"v":1.393013,"d":"1.39"},{"v":0.398933,"d":"0.40"},{"v":3.49184700187751,"d":"3.49"},{"v":1.80399034749306,"d":"1.80"},{"v":0.0311711934997826,"d":"0.03"},{"v":0.428391798950267,"d":"0.43"},"up","yes"]
["MSTRG.15314","TSR2","ENST00000375151","GO:0005515(protein binding);GO:0006364(rRNA processing);GO:0005634(nucleus);GO:0000462(maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA))","NA","NA","NA","TSR2, ribosome maturation factor [Source:HGNC Symbol;Acc:HGNC:25455]",{"v":4.153002,"d":"4.15"},{"v":9.37607,"d":"9.38"},{"v":0.442936326200636,"d":"0.44"},{"v":-1.17482877415901,"d":"-1.17"},{"v":0.0312757174914439,"d":"0.03"},{"v":0.429320221309856,"d":"0.43"},"down","yes"]
["MSTRG.5391","AKAP13","ENST00000394518;MSTRG.5391.22;ENST00000560579;ENST00000559362;ENST00000558166;ENST00000559486;ENST00000394510;ENST00000361243;ENST00000560957;ENST00000612418;ENST00000558644;MSTRG.5391.12;ENST00000559391;ENST00000557852;ENST00000558009;ENST00000559278;ENST00000558092;MSTRG.5391.21;ENST00000560340;ENST00000558811;ENST00000560302;MSTRG.5391.9;ENST00000560482","GO:0006468(protein phosphorylation);GO:0035023(regulation of Rho protein signal transduction);GO:0004691(cAMP-dependent protein kinase activity);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0046872(metal ion binding);GO:0005829(cytosol);GO:0035556(intracellular signal transduction);GO:0005089(Rho guanyl-nucleotide exchange factor activity);GO:0043547(positive regulation of GTPase activity);GO:0005515(protein binding);GO:0007186(G-protein coupled receptor signaling pathway);GO:0005085(guanyl-nucleotide exchange factor activity);GO:0051056(regulation of small GTPase mediated signal transduction);GO:0007507(heart development);GO:0060348(bone development);GO:0005938(cell cortex);GO:0043123(positive regulation of I-kappaB kinase/NF-kappaB signaling);GO:0004871(signal transducer activity);GO:0030864(cortical actin cytoskeleton);GO:0043065(positive regulation of apoptotic process);GO:0017048(Rho GTPase binding);GO:0032947(protein complex scaffold);GO:0051018(protein kinase A binding);GO:0035025(positive regulation of Rho protein signal transduction);GO:0055007(cardiac muscle cell differentiation);GO:0005078(MAP-kinase scaffold activity);GO:0060297(regulation of sarcomere organization);GO:0071875(adrenergic receptor signaling pathway);GO:0086023(adrenergic receptor signaling pathway involved in heart process);GO:0010611(regulation of cardiac muscle hypertrophy);GO:0045859(regulation of protein kinase activity);GO:0051168(nuclear export);GO:0071883(activation of MAPK activity by adrenergic receptor signaling pathway);GO:1900169(regulation of glucocorticoid mediated signaling pathway);GO:0005884(actin filament);GO:0015629(actin cytoskeleton);GO:0048471(perinuclear region of cytoplasm);GO:0005622(intracellular);GO:0005622(intracellular)","NA","NA","NA","A-kinase anchoring protein 13 [Source:HGNC Symbol;Acc:HGNC:371]",{"v":17.3475489749014,"d":"17.35"},{"v":5.32176220088757,"d":"5.32"},{"v":3.25973771845878,"d":"3.26"},{"v":1.7047558885357,"d":"1.70"},{"v":0.0313403539927414,"d":"0.03"},{"v":0.429699564247587,"d":"0.43"},"up","yes"]
["ENSG00000006432","MAP3K9","ENST00000554752","GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0042803(protein homodimerization activity);GO:0005515(protein binding);GO:0006915(apoptotic process);GO:0004709(MAP kinase kinase kinase activity);GO:0000186(activation of MAPKK activity);GO:0005737(cytoplasm);GO:0005575(cellular_component);GO:0046777(protein autophosphorylation);GO:0004708(MAP kinase kinase activity);GO:0007257(activation of JUN kinase activity);GO:0004706(JUN kinase kinase kinase activity);GO:0007256(activation of JNKK activity);GO:0008219(cell death);GO:0043065(positive regulation of apoptotic process);GO:0004713(protein tyrosine kinase activity);GO:0018108(peptidyl-tyrosine phosphorylation);GO:0005622(intracellular);GO:0000165(MAPK cascade)","NA","NA","NA","mitogen-activated protein kinase kinase kinase 9 [Source:HGNC Symbol;Acc:HGNC:6861]",{"v":0.42570247634426,"d":"0.43"},{"v":0.126965541740675,"d":"0.13"},{"v":3.35289772727273,"d":"3.35"},{"v":1.74540847758241,"d":"1.75"},{"v":0.0314846221980355,"d":"0.03"},{"v":0.431168534888898,"d":"0.43"},"up","yes"]
["ENSG00000244257","PKD1P1","ENST00000458669","NA","NA","NA","NA","polycystin 1, transient receptor potential channel interacting pseudogene 1 [Source:HGNC Symbol;Acc:HGNC:30065]",{"v":1.514726,"d":"1.51"},{"v":0.457216,"d":"0.46"},{"v":3.31293305571109,"d":"3.31"},{"v":1.72810905123981,"d":"1.73"},{"v":0.0315728421611914,"d":"0.03"},{"v":0.431606970358868,"d":"0.43"},"up","yes"]
["ENSG00000118620","ZNF430","ENST00000261560;ENST00000595401;ENST00000599548;ENST00000594110","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0005622(intracellular);GO:0021762(substantia nigra development);GO:0021762(substantia nigra development)","NA","NA","NA","zinc finger protein 430 [Source:HGNC Symbol;Acc:HGNC:20808]",{"v":0.578452011687363,"d":"0.58"},{"v":0.170414707085464,"d":"0.17"},{"v":3.39437846404457,"d":"3.39"},{"v":1.76314743045509,"d":"1.76"},{"v":0.0315909691556909,"d":"0.03"},{"v":0.431606970358868,"d":"0.43"},"up","yes"]
["ENSG00000213965","NUDT19","ENST00000397061","GO:0046872(metal ion binding);GO:0016787(hydrolase activity);GO:0005777(peroxisome);GO:0008150(biological_process);GO:0005575(cellular_component);GO:0005102(receptor binding);GO:0047617(acyl-CoA hydrolase activity);GO:0009062(fatty acid catabolic process);GO:0005739(mitochondrion);GO:0005782(peroxisomal matrix)","04146(Peroxisome)","K13355","EC:3.6.1.-","nudix hydrolase 19 [Source:HGNC Symbol;Acc:HGNC:32036]",{"v":1.601659,"d":"1.60"},{"v":0.476762,"d":"0.48"},{"v":3.35945188584661,"d":"3.36"},{"v":1.74822586810043,"d":"1.75"},{"v":0.0319197222185643,"d":"0.03"},{"v":0.435186549902599,"d":"0.44"},"up","yes"]
["ENSG00000184939","ZFP90","ENST00000570495;ENST00000398253;ENST00000573161;ENST00000562156;ENST00000571720;ENST00000564558;ENST00000570884;ENST00000576305;ENST00000576805;ENST00000563169;ENST00000564323;ENST00000611381;ENST00000573113;ENST00000569323;ENST00000566573","GO:0003676(nucleic acid binding);GO:0006355(regulation of transcription, DNA-templated);GO:0005622(intracellular);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0045893(positive regulation of transcription, DNA-templated);GO:0001078(transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0043392(negative regulation of DNA binding);GO:0045892(negative regulation of transcription, DNA-templated);GO:0045892(negative regulation of transcription, DNA-templated)","NA","NA","NA","ZFP90 zinc finger protein [Source:HGNC Symbol;Acc:HGNC:23329]",{"v":0.831730319030649,"d":"0.83"},{"v":1.89333383891661,"d":"1.89"},{"v":0.439294065280413,"d":"0.44"},{"v":-1.18674108566464,"d":"-1.19"},{"v":0.0319279204785167,"d":"0.03"},{"v":0.435186549902599,"d":"0.44"},"down","yes"]
["ENSG00000144218","AFF3","ENST00000409236;ENST00000317233;ENST00000445815;ENST00000415384;ENST00000423966;ENST00000430789;ENST00000427118;ENST00000498090;ENST00000432037;ENST00000409579;ENST00000424600;ENST00000416492;ENST00000483600","GO:0005634(nucleus);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0016604(nuclear body);GO:0035116(embryonic hindlimb morphogenesis);GO:0034612(response to tumor necrosis factor);GO:0003690(double-stranded DNA binding);GO:0003690(double-stranded DNA binding)","NA","NA","NA","AF4/FMR2 family member 3 [Source:HGNC Symbol;Acc:HGNC:6473]",{"v":1.11355617955563,"d":"1.11"},{"v":0.337720620318756,"d":"0.34"},{"v":3.29727032511253,"d":"3.30"},{"v":1.72127217051209,"d":"1.72"},{"v":0.0320029016519871,"d":"0.03"},{"v":0.435616028290674,"d":"0.44"},"up","yes"]
["MSTRG.15446","TENM1","ENST00000422452","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016607(nuclear speck);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0007165(signal transduction);GO:0005794(Golgi apparatus);GO:0005783(endoplasmic reticulum);GO:0042803(protein homodimerization activity);GO:0005886(plasma membrane);GO:0005856(cytoskeleton);GO:0048471(perinuclear region of cytoplasm);GO:0007218(neuropeptide signaling pathway);GO:0005887(integral component of plasma membrane);GO:0033138(positive regulation of peptidyl-serine phosphorylation);GO:0043005(neuron projection);GO:0007399(nervous system development);GO:0006955(immune response);GO:0016363(nuclear matrix);GO:0046982(protein heterodimerization activity);GO:0005576(extracellular region);GO:0051491(positive regulation of filopodium assembly);GO:0008285(negative regulation of cell proliferation);GO:0030838(positive regulation of actin filament polymerization);GO:0050839(cell adhesion molecule binding);GO:0007157(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules);GO:0090316(positive regulation of intracellular protein transport);GO:0043406(positive regulation of MAP kinase activity);GO:0000902(cell morphogenesis);GO:0008201(heparin binding);GO:0048666(neuron development);GO:0006359(regulation of transcription from RNA polymerase III promoter)","NA","NA","NA","teneurin transmembrane protein 1 [Source:HGNC Symbol;Acc:HGNC:8117]",{"v":0.356704645859181,"d":"0.36"},{"v":0.106171819401365,"d":"0.11"},{"v":3.35969231638311,"d":"3.36"},{"v":1.7483291157559,"d":"1.75"},{"v":0.0320344517489224,"d":"0.03"},{"v":0.435616028290674,"d":"0.44"},"up","yes"]
["ENSG00000204842","ATXN2","ENST00000483311;ENST00000482777;ENST00000484991;ENST00000392645;ENST00000377617;ENST00000535949;ENST00000550844;ENST00000389154;ENST00000475132;ENST00000542287;ENST00000492467;ENST00000608853;ENST00000389153;ENST00000550889;ENST00000552323;ENST00000550104;ENST00000616825;ENST00000495342;ENST00000551755;ENST00000551551;ENST00000481331;ENST00000546483","GO:0003723(RNA binding);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0030529(intracellular ribonucleoprotein complex);GO:0005794(Golgi apparatus);GO:0005515(protein binding);GO:0048471(perinuclear region of cytoplasm);GO:0005802(trans-Golgi network);GO:0006417(regulation of translation);GO:0008022(protein C-terminus binding);GO:0010494(cytoplasmic stress granule);GO:0002091(negative regulation of receptor internalization);GO:0034063(stress granule assembly);GO:0005154(epidermal growth factor receptor binding);GO:0016070(RNA metabolic process);GO:0005844(polysome);GO:0033962(cytoplasmic mRNA processing body assembly);GO:0010603(regulation of cytoplasmic mRNA processing body assembly);GO:0050658(RNA transport);GO:0050658(RNA transport)","NA","NA","NA","ataxin 2 [Source:HGNC Symbol;Acc:HGNC:10555]",{"v":1.1422530808871,"d":"1.14"},{"v":0.343274482882366,"d":"0.34"},{"v":3.32752108836045,"d":"3.33"},{"v":1.73444780933074,"d":"1.73"},{"v":0.0321205704742731,"d":"0.03"},{"v":0.436117604762559,"d":"0.44"},"up","yes"]
["MSTRG.4643","DICER1","ENST00000343455;ENST00000554367;ENST00000526495;ENST00000529720;ENST00000556045;ENST00000527416;ENST00000527554;ENST00000527414;ENST00000532939;ENST00000556681;ENST00000393063;ENST00000531162;ENST00000541352;ENST00000529206","GO:0070062(extracellular exosome);GO:0003723(RNA binding);GO:0006396(RNA processing);GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0016787(hydrolase activity);GO:0003677(DNA binding);GO:0004386(helicase activity);GO:0005515(protein binding);GO:0004519(endonuclease activity);GO:0004518(nuclease activity);GO:0004525(ribonuclease III activity);GO:0031047(gene silencing by RNA);GO:0005634(nucleus);GO:0005829(cytosol);GO:0019904(protein domain specific binding);GO:0016891(endoribonuclease activity, producing 5'-phosphomonoesters);GO:0006309(apoptotic DNA fragmentation);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0030422(production of siRNA involved in RNA interference);GO:0021675(nerve development);GO:0003725(double-stranded RNA binding);GO:0070883(pre-miRNA binding);GO:0010586(miRNA metabolic process);GO:0031054(pre-miRNA processing);GO:0035196(production of miRNAs involved in gene silencing by miRNA);GO:0070578(RISC-loading complex);GO:0048812(neuron projection morphogenesis);GO:0030423(targeting of mRNA for destruction involved in RNA interference);GO:0035280(miRNA loading onto RISC involved in gene silencing by miRNA);GO:0035197(siRNA binding);GO:0004521(endoribonuclease activity);GO:0035087(siRNA loading onto RISC involved in RNA interference);GO:0004530(deoxyribonuclease I activity);GO:0010626(negative regulation of Schwann cell proliferation);GO:0014040(positive regulation of Schwann cell differentiation);GO:0031643(positive regulation of myelination);GO:0032290(peripheral nervous system myelin formation);GO:0033168(conversion of ds siRNA to ss siRNA involved in RNA interference);GO:0036404(conversion of ds siRNA to ss siRNA);GO:0090502(RNA phosphodiester bond hydrolysis, endonucleolytic);GO:0033167(ARC complex);GO:0005793(endoplasmic reticulum-Golgi intermediate compartment);GO:0030424(axon);GO:0030425(dendrite);GO:0030426(growth cone);GO:0090501(RNA phosphodiester bond hydrolysis);GO:0090501(RNA phosphodiester bond hydrolysis)","05206(MicroRNAs in cancer);05206(MicroRNAs in cancer)","K11592","EC:3.1.26.-","dicer 1, ribonuclease III [Source:HGNC Symbol;Acc:HGNC:17098]",{"v":9.18650604563202,"d":"9.19"},{"v":2.83013260200098,"d":"2.83"},{"v":3.24596311817224,"d":"3.25"},{"v":1.69864660754691,"d":"1.70"},{"v":0.0321761452351684,"d":"0.03"},{"v":0.436117604762559,"d":"0.44"},"up","yes"]
["MSTRG.12945","RPS18","ENST00000490191;ENST00000439602;ENST00000474973;ENST00000474626;ENST00000479802;ENST00000472218;ENST00000476222;ENST00000496813","GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0006412(translation);GO:0005829(cytosol);GO:0030529(intracellular ribonucleoprotein complex);GO:0005622(intracellular);GO:0003735(structural constituent of ribosome);GO:0005840(ribosome);GO:0022627(cytosolic small ribosomal subunit);GO:0005925(focal adhesion);GO:0005515(protein binding);GO:0005654(nucleoplasm);GO:0070062(extracellular exosome);GO:0031012(extracellular matrix);GO:0019843(rRNA binding);GO:0042254(ribosome biogenesis);GO:0006413(translational initiation);GO:0006364(rRNA processing);GO:0000184(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay);GO:0019083(viral transcription);GO:0006614(SRP-dependent cotranslational protein targeting to membrane);GO:0015935(small ribosomal subunit);GO:0005581(collagen trimer);GO:0005581(collagen trimer)","03010(Ribosome);03010(Ribosome)","K02964","NA","ribosomal protein S18 [Source:HGNC Symbol;Acc:HGNC:10401]",{"v":261.328714899368,"d":"261.33"},{"v":582.9619009647,"d":"582.96"},{"v":0.448277519451811,"d":"0.45"},{"v":-1.15753594300847,"d":"-1.16"},{"v":0.0321839995936892,"d":"0.03"},{"v":0.436117604762559,"d":"0.44"},"down","yes"]
["MSTRG.8651","SOS1","ENST00000395038;ENST00000461545;ENST00000469581;ENST00000474390;ENST00000426016;ENST00000402219;ENST00000451331","GO:0007264(small GTPase mediated signal transduction);GO:0003677(DNA binding);GO:0046982(protein heterodimerization activity);GO:0005089(Rho guanyl-nucleotide exchange factor activity);GO:0035023(regulation of Rho protein signal transduction);GO:0043547(positive regulation of GTPase activity);GO:0005515(protein binding);GO:0005085(guanyl-nucleotide exchange factor activity);GO:0038095(Fc-epsilon receptor signaling pathway);GO:0050900(leukocyte migration);GO:0005886(plasma membrane);GO:0005829(cytosol);GO:0051056(regulation of small GTPase mediated signal transduction);GO:0000165(MAPK cascade);GO:0007165(signal transduction);GO:0007411(axon guidance);GO:0005088(Ras guanyl-nucleotide exchange factor activity);GO:0038128(ERBB2 signaling pathway);GO:0005737(cytoplasm);GO:0007265(Ras protein signal transduction);GO:0043065(positive regulation of apoptotic process);GO:0005096(GTPase activator activity);GO:0008286(insulin receptor signaling pathway);GO:0007173(epidermal growth factor receptor signaling pathway);GO:0017124(SH3 domain binding);GO:0001782(B cell homeostasis);GO:0001942(hair follicle development);GO:0002260(lymphocyte homeostasis);GO:0003007(heart morphogenesis);GO:0003209(cardiac atrium morphogenesis);GO:0003344(pericardium morphogenesis);GO:0007296(vitellogenesis);GO:0033081(regulation of T cell differentiation in thymus);GO:0035264(multicellular organism growth);GO:0042129(regulation of T cell proliferation);GO:0045742(positive regulation of epidermal growth factor receptor signaling pathway);GO:0048011(neurotrophin TRK receptor signaling pathway);GO:0048514(blood vessel morphogenesis);GO:0051057(positive regulation of small GTPase mediated signal transduction);GO:0060021(palate development);GO:0061029(eyelid development in camera-type eye);GO:0061384(heart trabecula morphogenesis);GO:1904693(midbrain morphogenesis);GO:2000973(regulation of pro-B cell differentiation);GO:0014069(postsynaptic density);GO:0043025(neuronal cell body);GO:0005622(intracellular);GO:0005622(intracellular)","04014(Ras signaling pathway);04010(MAPK signaling pathway);04012(ErbB signaling pathway);04630(Jak-STAT signaling pathway);04068(FoxO signaling pathway);04072(Phospholipase D signaling pathway);04151(PI3K-Akt signaling pathway);04150(mTOR signaling pathway);04510(Focal adhesion);04540(Gap junction);04810(Regulation of actin cytoskeleton);04650(Natural killer cell mediated cytotoxicity);04660(T cell receptor signaling pathway);04662(B cell receptor signaling pathway);04664(Fc epsilon RI signaling pathway);04062(Chemokine signaling pathway);04910(Insulin signaling pathway);04912(GnRH signaling pathway);04915(Estrogen signaling pathway);04917(Prolactin signaling pathway);04926(Relaxin signaling pathway);04722(Neurotrophin signaling pathway);05200(Pathways in cancer);05231(Choline metabolism in cancer);05206(MicroRNAs in cancer);05205(Proteoglycans in cancer);05225(Hepatocellular carcinoma);05226(Gastric cancer);05214(Glioma);05221(Acute myeloid leukemia);05220(Chronic myeloid leukemia);05211(Renal cell carcinoma);05215(Prostate cancer);05213(Endometrial cancer);05224(Breast cancer);05223(Non-small cell lung cancer);05034(Alcoholism);05160(Hepatitis C);05165(Human papillomavirus infection);01521(EGFR tyrosine kinase inhibitor resistance);01522(Endocrine resistance);01522(Endocrine resistance)","K03099","NA","SOS Ras/Rac guanine nucleotide exchange factor 1 [Source:HGNC Symbol;Acc:HGNC:11187]",{"v":4.12341155262874,"d":"4.12"},{"v":1.26788886958869,"d":"1.27"},{"v":3.25218688445967,"d":"3.25"},{"v":1.70141016317443,"d":"1.70"},{"v":0.0323252537285571,"d":"0.03"},{"v":0.437026564982522,"d":"0.44"},"up","yes"]
["ENSG00000110987","BCL7A","ENST00000432926;ENST00000538010;ENST00000261822","GO:0005515(protein binding);GO:0003674(molecular_function);GO:0005575(cellular_component);GO:0045892(negative regulation of transcription, DNA-templated);GO:0045892(negative regulation of transcription, DNA-templated)","NA","NA","NA","BCL tumor suppressor 7A [Source:HGNC Symbol;Acc:HGNC:1004]",{"v":0.171624710586443,"d":"0.17"},{"v":0.403543165270373,"d":"0.40"},{"v":0.425294554230536,"d":"0.43"},{"v":-1.23346571308357,"d":"-1.23"},{"v":0.0323263428330308,"d":"0.03"},{"v":0.437026564982522,"d":"0.44"},"down","yes"]
["ENSG00000185920","PTCH1","ENST00000429896;ENST00000550914;ENST00000551630;ENST00000488809;ENST00000375271;ENST00000553256;ENST00000331920;ENST00000375290;ENST00000430669;ENST00000546744;ENST00000549678;ENST00000550136;ENST00000548420;ENST00000421141","GO:0048471(perinuclear region of cytoplasm);GO:0043433(negative regulation of sequence-specific DNA binding transcription factor activity);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005515(protein binding);GO:0007224(smoothened signaling pathway);GO:0060037(pharyngeal system development);GO:0005886(plasma membrane);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0030666(endocytic vesicle membrane);GO:0009887(animal organ morphogenesis);GO:0009953(dorsal/ventral pattern formation);GO:0005901(caveola);GO:0005794(Golgi apparatus);GO:0045668(negative regulation of osteoblast differentiation);GO:0071397(cellular response to cholesterol);GO:0015485(cholesterol binding);GO:0040015(negative regulation of multicellular organism growth);GO:0010875(positive regulation of cholesterol efflux);GO:0072001(renal system development);GO:0007420(brain development);GO:0043231(intracellular membrane-bounded organelle);GO:0060170(ciliary membrane);GO:0008589(regulation of smoothened signaling pathway);GO:0016485(protein processing);GO:0045879(negative regulation of smoothened signaling pathway);GO:0061053(somite development);GO:0072661(protein targeting to plasma membrane);GO:0030326(embryonic limb morphogenesis);GO:0030332(cyclin binding);GO:0005113(patched binding);GO:0005119(smoothened binding);GO:0008158(hedgehog receptor activity);GO:0008201(heparin binding);GO:0032403(protein complex binding);GO:0097108(hedgehog family protein binding);GO:0001658(branching involved in ureteric bud morphogenesis);GO:0001701(in utero embryonic development);GO:0001709(cell fate determination);GO:0001841(neural tube formation);GO:0001843(neural tube closure);GO:0003007(heart morphogenesis);GO:0007165(signal transduction);GO:0007346(regulation of mitotic cell cycle);GO:0007389(pattern specification process);GO:0008285(negative regulation of cell proliferation);GO:0008544(epidermis development);GO:0009612(response to mechanical stimulus);GO:0009957(epidermal cell fate specification);GO:0010157(response to chlorate);GO:0014070(response to organic cyclic compound);GO:0021522(spinal cord motor neuron differentiation);GO:0021532(neural tube patterning);GO:0021904(dorsal/ventral neural tube patterning);GO:0021997(neural plate axis specification);GO:0030850(prostate gland development);GO:0030879(mammary gland development);GO:0032355(response to estradiol);GO:0032526(response to retinoic acid);GO:0032880(regulation of protein localization);GO:0035108(limb morphogenesis);GO:0035137(hindlimb morphogenesis);GO:0040008(regulation of growth);GO:0042127(regulation of cell proliferation);GO:0042493(response to drug);GO:0042593(glucose homeostasis);GO:0043616(keratinocyte proliferation);GO:0045606(positive regulation of epidermal cell differentiation);GO:0045892(negative regulation of transcription, DNA-templated);GO:0045893(positive regulation of transcription, DNA-templated);GO:0048568(embryonic organ development);GO:0050680(negative regulation of epithelial cell proliferation);GO:0051782(negative regulation of cell division);GO:0060603(mammary gland duct morphogenesis);GO:0060644(mammary gland epithelial cell differentiation);GO:0060831(smoothened signaling pathway involved in dorsal/ventral neural tube patterning);GO:0061005(cell differentiation involved in kidney development);GO:0071679(commissural neuron axon guidance);GO:0072203(cell proliferation involved in metanephros development);GO:0005634(nucleus);GO:0005929(cilium);GO:0014069(postsynaptic density);GO:0030496(midbody);GO:0044294(dendritic growth cone);GO:0044295(axonal growth cone);GO:0044295(axonal growth cone)","04340(Hedgehog signaling pathway);04024(cAMP signaling pathway);04360(Axon guidance);05200(Pathways in cancer);05205(Proteoglycans in cancer);05217(Basal cell carcinoma);05217(Basal cell carcinoma)","K06225","NA","patched 1 [Source:HGNC Symbol;Acc:HGNC:9585]",{"v":1.36581035579531,"d":"1.37"},{"v":0.418033219637153,"d":"0.42"},{"v":3.26722923355425,"d":"3.27"},{"v":1.70806767990911,"d":"1.71"},{"v":0.0324025499753738,"d":"0.03"},{"v":0.437194633568459,"d":"0.44"},"up","yes"]
["MSTRG.1999","EIF3A","ENST00000369144;ENST00000462527","GO:0003723(RNA binding);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0003743(translation initiation factor activity);GO:0006412(translation);GO:0006413(translational initiation);GO:0005852(eukaryotic translation initiation factor 3 complex);GO:0005634(nucleus);GO:0005730(nucleolus);GO:0005829(cytosol);GO:0005515(protein binding);GO:0003729(mRNA binding);GO:0075522(IRES-dependent viral translational initiation);GO:0071541(eukaryotic translation initiation factor 3 complex, eIF3m);GO:0005198(structural molecule activity);GO:0075525(viral translational termination-reinitiation);GO:0002188(translation reinitiation);GO:0043614(multi-eIF complex);GO:0030971(receptor tyrosine kinase binding);GO:0001732(formation of cytoplasmic translation initiation complex);GO:0070373(negative regulation of ERK1 and ERK2 cascade);GO:0005874(microtubule);GO:0071540(eukaryotic translation initiation factor 3 complex, eIF3e);GO:0071540(eukaryotic translation initiation factor 3 complex, eIF3e)","03013(RNA transport);03013(RNA transport)","K03254","NA","eukaryotic translation initiation factor 3 subunit A [Source:HGNC Symbol;Acc:HGNC:3271]",{"v":22.7235477206027,"d":"22.72"},{"v":7.01669255963949,"d":"7.02"},{"v":3.23849841324247,"d":"3.24"},{"v":1.6953250372087,"d":"1.70"},{"v":0.032419209673943,"d":"0.03"},{"v":0.437194633568459,"d":"0.44"},"up","yes"]
["ENSG00000183091","NEB","ENST00000618972;ENST00000489048;ENST00000483418;ENST00000480784;ENST00000497809","GO:0005737(cytoplasm);GO:0003779(actin binding);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0015629(actin cytoskeleton);GO:0030018(Z disc);GO:0007517(muscle organ development);GO:0008307(structural constituent of muscle);GO:0030049(muscle filament sliding);GO:0030017(sarcomere);GO:0007525(somatic muscle development);GO:0030832(regulation of actin filament length);GO:0030016(myofibril);GO:0043292(contractile fiber);GO:0043292(contractile fiber)","NA","NA","NA","nebulin [Source:HGNC Symbol;Acc:HGNC:7720]",{"v":0.114232665358066,"d":"0.11"},{"v":0.0334887701769883,"d":"0.03"},{"v":3.41107376455886,"d":"3.41"},{"v":1.77022595360643,"d":"1.77"},{"v":0.0324517156751926,"d":"0.03"},{"v":0.437194633568459,"d":"0.44"},"up","yes"]
["ENSG00000180900","SCRIB","ENST00000356994;ENST00000546337;ENST00000320476;ENST00000526832;ENST00000525051;ENST00000531163","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005654(nucleoplasm);GO:0005886(plasma membrane);GO:0030054(cell junction);GO:0042995(cell projection);GO:0005515(protein binding);GO:0007275(multicellular organism development);GO:0045211(postsynaptic membrane);GO:0030154(cell differentiation);GO:0098793(presynapse);GO:0045296(cadherin binding);GO:0030027(lamellipodium);GO:0031252(cell leading edge);GO:0070062(extracellular exosome);GO:0016323(basolateral plasma membrane);GO:0008283(cell proliferation);GO:0090630(activation of GTPase activity);GO:0005912(adherens junction);GO:0043065(positive regulation of apoptotic process);GO:0016032(viral process);GO:0046037(GMP metabolic process);GO:0046710(GDP metabolic process);GO:0007268(chemical synaptic transmission);GO:0016477(cell migration);GO:0042734(presynaptic membrane);GO:0005911(cell-cell junction);GO:0045930(negative regulation of mitotic cell cycle);GO:0001843(neural tube closure);GO:0016337(single organismal cell-cell adhesion);GO:0050918(positive chemotaxis);GO:0001921(positive regulation of receptor recycling);GO:0005913(cell-cell adherens junction);GO:0060603(mammary gland duct morphogenesis);GO:0071896(protein localization to adherens junction);GO:0014069(postsynaptic density);GO:0060561(apoptotic process involved in morphogenesis);GO:0008328(ionotropic glutamate receptor complex);GO:0004385(guanylate kinase activity);GO:0035255(ionotropic glutamate receptor binding);GO:0045197(establishment or maintenance of epithelial cell apical/basal polarity);GO:0097120(receptor localization to synapse);GO:0043113(receptor clustering);GO:0002093(auditory receptor cell morphogenesis);GO:0008105(asymmetric protein localization);GO:0016080(synaptic vesicle targeting);GO:0016331(morphogenesis of embryonic epithelium);GO:0021747(cochlear nucleus development);GO:0035089(establishment of apical/basal cell polarity);GO:0042060(wound healing);GO:0043615(astrocyte cell migration);GO:0048488(synaptic vesicle endocytosis);GO:0060088(auditory receptor cell stereocilium organization);GO:0098887(neurotransmitter receptor transport, endosome to postsynaptic membrane);GO:0098968(neurotransmitter receptor transport postsynaptic membrane to endosome);GO:0034750(Scrib-APC-beta-catenin complex);GO:0035748(myelin sheath abaxonal region);GO:0044291(cell-cell contact zone);GO:0044291(cell-cell contact zone)","04390(Hippo signaling pathway);04530(Tight junction);05203(Viral carcinogenesis);05165(Human papillomavirus infection);05165(Human papillomavirus infection)","K16175","NA","scribbled planar cell polarity protein [Source:HGNC Symbol;Acc:HGNC:30377]",{"v":3.1044150500646,"d":"3.10"},{"v":0.952682545542636,"d":"0.95"},{"v":3.25860389128507,"d":"3.26"},{"v":1.70425399190151,"d":"1.70"},{"v":0.0326112508137253,"d":"0.03"},{"v":0.4388348269986,"d":"0.44"},"up","yes"]
["ENSG00000173041","ZNF680","ENST00000309683;ENST00000447137;ENST00000473601;ENST00000476563","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0005622(intracellular);GO:0005622(intracellular)","NA","NA","NA","zinc finger protein 680 [Source:HGNC Symbol;Acc:HGNC:26897]",{"v":0.336189464196205,"d":"0.34"},{"v":0.774903486215539,"d":"0.77"},{"v":0.433846885678734,"d":"0.43"},{"v":-1.20474212191162,"d":"-1.20"},{"v":0.0326806580399444,"d":"0.03"},{"v":0.439259816918837,"d":"0.44"},"down","yes"]
["MSTRG.6930","KANSL1","ENST00000432791;ENST00000572218;ENST00000571698;ENST00000639279;ENST00000639520;ENST00000639150;ENST00000573682;ENST00000639853;ENST00000574655;ENST00000576739;ENST00000638902;ENST00000638275;ENST00000639375;ENST00000639467;ENST00000638269;ENST00000262419;ENST00000573286;ENST00000576870;ENST00000639531;ENST00000640092;ENST00000576137;ENST00000574590;ENST00000574963;ENST00000639099;ENST00000640519","GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0016569(covalent chromatin modification);GO:0005694(chromosome);GO:0005515(protein binding);GO:0000123(histone acetyltransferase complex);GO:0000775(chromosome, centromeric region);GO:0000776(kinetochore);GO:0000777(condensed chromosome kinetochore);GO:0071339(MLL1 complex);GO:0043995(histone acetyltransferase activity (H4-K5 specific));GO:0043996(histone acetyltransferase activity (H4-K8 specific));GO:0046972(histone acetyltransferase activity (H4-K16 specific));GO:0043981(histone H4-K5 acetylation);GO:0043982(histone H4-K8 acetylation);GO:0043984(histone H4-K16 acetylation);GO:0043984(histone H4-K16 acetylation)","NA","NA","NA","KAT8 regulatory NSL complex subunit 1 [Source:HGNC Symbol;Acc:HGNC:24565]",{"v":2.69502424507952,"d":"2.70"},{"v":0.830319070124638,"d":"0.83"},{"v":3.2457694181045,"d":"3.25"},{"v":1.69856051338772,"d":"1.70"},{"v":0.032786135247707,"d":"0.03"},{"v":0.439874654927511,"d":"0.44"},"up","yes"]
["ENSG00000149557","FEZ1","ENST00000278919;ENST00000392709;ENST00000532981;ENST00000524435;ENST00000528863;ENST00000366139;ENST00000534022;ENST00000577924;ENST00000533294;ENST00000527534;ENST00000524427","GO:0006810(transport);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005886(plasma membrane);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0005874(microtubule);GO:0005815(microtubule organizing center);GO:0005794(Golgi apparatus);GO:0007399(nervous system development);GO:0007155(cell adhesion);GO:0007411(axon guidance);GO:0030424(axon);GO:0005080(protein kinase C binding);GO:0043015(gamma-tubulin binding);GO:0047485(protein N-terminus binding);GO:0010976(positive regulation of neuron projection development);GO:0045666(positive regulation of neuron differentiation);GO:0051654(establishment of mitochondrion localization);GO:0071363(cellular response to growth factor stimulus);GO:1902902(negative regulation of autophagosome assembly);GO:0005739(mitochondrion);GO:0005813(centrosome);GO:0030425(dendrite);GO:0042995(cell projection);GO:0042995(cell projection)","NA","NA","NA","fasciculation and elongation protein zeta 1 [Source:HGNC Symbol;Acc:HGNC:3659]",{"v":0.42899392538319,"d":"0.43"},{"v":0.983134587670541,"d":"0.98"},{"v":0.436353202057164,"d":"0.44"},{"v":-1.19643171087101,"d":"-1.20"},{"v":0.032802157165868,"d":"0.03"},{"v":0.439874654927511,"d":"0.44"},"down","yes"]
["MSTRG.10980","DNAH1","ENST00000486752;ENST00000490713;ENST00000488988;ENST00000487254;ENST00000497875;ENST00000480649","GO:0005737(cytoplasm);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0003777(microtubule motor activity);GO:0005856(cytoskeleton);GO:0042995(cell projection);GO:0005874(microtubule);GO:0003774(motor activity);GO:0007018(microtubule-based movement);GO:0016887(ATPase activity);GO:0030286(dynein complex);GO:0003341(cilium movement);GO:0003351(epithelial cilium movement);GO:0030317(flagellated sperm motility);GO:0060294(cilium movement involved in cell motility);GO:0005858(axonemal dynein complex);GO:0036126(sperm flagellum);GO:0005929(cilium);GO:0051959(dynein light intermediate chain binding);GO:0045503(dynein light chain binding);GO:0045505(dynein intermediate chain binding);GO:0060285(cilium-dependent cell motility);GO:0008569(ATP-dependent microtubule motor activity, minus-end-directed);GO:0036159(inner dynein arm assembly);GO:0036156(inner dynein arm);GO:0036156(inner dynein arm)","05016(Huntington's disease);05016(Huntington's disease)","NA","NA","dynein axonemal heavy chain 1 [Source:HGNC Symbol;Acc:HGNC:2940]",{"v":2.0752731378316,"d":"2.08"},{"v":0.639758013624568,"d":"0.64"},{"v":3.24384078610298,"d":"3.24"},{"v":1.69770301106673,"d":"1.70"},{"v":0.0328969039246499,"d":"0.03"},{"v":0.440636384402491,"d":"0.44"},"up","yes"]
["MSTRG.15073","MED22","ENST00000610888;ENST00000343730;ENST00000482295;ENST00000457204;ENST00000610672","GO:0005634(nucleus);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0001104(RNA polymerase II transcription cofactor activity);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0016592(mediator complex);GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0005737(cytoplasm)","NA","NA","NA","mediator complex subunit 22 [Source:HGNC Symbol;Acc:HGNC:11477]",{"v":0.984136398671096,"d":"0.98"},{"v":2.20970562790698,"d":"2.21"},{"v":0.445369910924861,"d":"0.45"},{"v":-1.16692400157041,"d":"-1.17"},{"v":0.0329463356279074,"d":"0.03"},{"v":0.440790087150793,"d":"0.44"},"down","yes"]
["MSTRG.14483","VPS13B","ENST00000357162;ENST00000358544;ENST00000493587;ENST00000441350;ENST00000496144;ENST00000521932;ENST00000355155","GO:0006810(transport);GO:0015031(protein transport);GO:0015031(protein transport)","NA","NA","NA","vacuolar protein sorting 13 homolog B [Source:HGNC Symbol;Acc:HGNC:2183]",{"v":4.09160165236899,"d":"4.09"},{"v":1.26609831335248,"d":"1.27"},{"v":3.23166187745319,"d":"3.23"},{"v":1.69227625958729,"d":"1.69"},{"v":0.0331355194083302,"d":"0.03"},{"v":0.442811032093139,"d":"0.44"},"up","yes"]
["ENSG00000011114","BTBD7","ENST00000334746;ENST00000298896;ENST00000555525;ENST00000355125;ENST00000554968;ENST00000554644;ENST00000554565","GO:0005634(nucleus);GO:0007275(multicellular organism development);GO:0007275(multicellular organism development)","NA","NA","NA","BTB domain containing 7 [Source:HGNC Symbol;Acc:HGNC:18269]",{"v":2.31500532400953,"d":"2.32"},{"v":0.714476692755669,"d":"0.71"},{"v":3.2401411375377,"d":"3.24"},{"v":1.69605665693427,"d":"1.70"},{"v":0.0332033268245008,"d":"0.03"},{"v":0.443029501399399,"d":"0.44"},"up","yes"]
["MSTRG.7720","ALKBH7","ENST00000245812","GO:0046872(metal ion binding);GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0006631(fatty acid metabolic process);GO:0005739(mitochondrion);GO:0006974(cellular response to DNA damage stimulus);GO:0005759(mitochondrial matrix);GO:0051213(dioxygenase activity);GO:1902445(regulation of mitochondrial membrane permeability involved in programmed necrotic cell death);GO:0012501(programmed cell death);GO:0010883(regulation of lipid storage)","NA","NA","NA","alkB homolog 7 [Source:HGNC Symbol;Acc:HGNC:21306]",{"v":5.9707032742268,"d":"5.97"},{"v":13.3245150680412,"d":"13.32"},{"v":0.448099104825774,"d":"0.45"},{"v":-1.15811025048734,"d":"-1.16"},{"v":0.0332281663410726,"d":"0.03"},{"v":0.443029501399399,"d":"0.44"},"down","yes"]
["MSTRG.1183","F5","ENST00000367796;ENST00000495481;ENST00000367797","GO:0016020(membrane);GO:0046872(metal ion binding);GO:0005576(extracellular region);GO:0007596(blood coagulation);GO:0005507(copper ion binding);GO:0005886(plasma membrane);GO:0000139(Golgi membrane);GO:0005515(protein binding);GO:0044267(cellular protein metabolic process);GO:0043687(post-translational protein modification);GO:0002576(platelet degranulation);GO:0007599(hemostasis);GO:0005788(endoplasmic reticulum lumen);GO:0031093(platelet alpha granule lumen);GO:0006888(ER to Golgi vesicle-mediated transport);GO:1903561(extracellular vesicle);GO:0048208(COPII vesicle coating);GO:0033116(endoplasmic reticulum-Golgi intermediate compartment membrane);GO:0030134(ER to Golgi transport vesicle);GO:0008015(blood circulation);GO:0032571(response to vitamin K);GO:0005615(extracellular space);GO:0005783(endoplasmic reticulum);GO:0005794(Golgi apparatus);GO:0031091(platelet alpha granule);GO:0031091(platelet alpha granule)","04610(Complement and coagulation cascades);04610(Complement and coagulation cascades)","K03902","NA","coagulation factor V [Source:HGNC Symbol;Acc:HGNC:3542]",{"v":5.9516239709416,"d":"5.95"},{"v":1.84358565982118,"d":"1.84"},{"v":3.22828719090757,"d":"3.23"},{"v":1.6907689275835,"d":"1.69"},{"v":0.0334631877834742,"d":"0.03"},{"v":0.445651375836566,"d":"0.45"},"up","yes"]
["ENSG00000102755","FLT1","ENST00000282397;ENST00000615840;ENST00000541932","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0004713(protein tyrosine kinase activity);GO:0007169(transmembrane receptor protein tyrosine kinase signaling pathway);GO:0018108(peptidyl-tyrosine phosphorylation);GO:0005887(integral component of plasma membrane);GO:0005886(plasma membrane);GO:0015629(actin cytoskeleton);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0004714(transmembrane receptor protein tyrosine kinase activity);GO:0007275(multicellular organism development);GO:0005021(vascular endothelial growth factor-activated receptor activity);GO:0030154(cell differentiation);GO:0005925(focal adhesion);GO:0038084(vascular endothelial growth factor signaling pathway);GO:0048010(vascular endothelial growth factor receptor signaling pathway);GO:0006935(chemotaxis);GO:0005768(endosome);GO:0030335(positive regulation of cell migration);GO:0005615(extracellular space);GO:0016477(cell migration);GO:0046777(protein autophosphorylation);GO:0001525(angiogenesis);GO:0019838(growth factor binding);GO:0045766(positive regulation of angiogenesis);GO:0035924(cellular response to vascular endothelial growth factor stimulus);GO:0043235(receptor complex);GO:0043410(positive regulation of MAPK cascade);GO:0014068(positive regulation of phosphatidylinositol 3-kinase signaling);GO:0048514(blood vessel morphogenesis);GO:0008284(positive regulation of cell proliferation);GO:0043406(positive regulation of MAP kinase activity);GO:0043552(positive regulation of phosphatidylinositol 3-kinase activity);GO:0030949(positive regulation of vascular endothelial growth factor receptor signaling pathway);GO:0010863(positive regulation of phospholipase C activity);GO:0002548(monocyte chemotaxis);GO:0036326(VEGF-A-activated receptor activity);GO:0036327(VEGF-B-activated receptor activity);GO:0036332(placental growth factor-activated receptor activity);GO:0036323(vascular endothelial growth factor receptor-1 signaling pathway);GO:0048598(embryonic morphogenesis);GO:0048598(embryonic morphogenesis)","04014(Ras signaling pathway);04015(Rap1 signaling pathway);04010(MAPK signaling pathway);04066(HIF-1 signaling pathway);04151(PI3K-Akt signaling pathway);04060(Cytokine-cytokine receptor interaction);04510(Focal adhesion);05202(Transcriptional misregulation in cancers);05323(Rheumatoid arthritis);05323(Rheumatoid arthritis)","K05096","EC:2.7.10.1","fms related tyrosine kinase 1 [Source:HGNC Symbol;Acc:HGNC:3763]",{"v":0.23073397763985,"d":"0.23"},{"v":0.0685329720697064,"d":"0.07"},{"v":3.36675866625433,"d":"3.37"},{"v":1.75136031056964,"d":"1.75"},{"v":0.0338420389660003,"d":"0.03"},{"v":0.448643262685613,"d":"0.45"},"up","yes"]
["MSTRG.8136","PLEKHG2","ENST00000425673;ENST00000594307;ENST00000451354;ENST00000596443;ENST00000458508;ENST00000474449;ENST00000478523","GO:0005089(Rho guanyl-nucleotide exchange factor activity);GO:0035023(regulation of Rho protein signal transduction);GO:0043547(positive regulation of GTPase activity);GO:0005085(guanyl-nucleotide exchange factor activity);GO:0005829(cytosol);GO:0051056(regulation of small GTPase mediated signal transduction);GO:0043065(positive regulation of apoptotic process);GO:0030833(regulation of actin filament polymerization);GO:0030833(regulation of actin filament polymerization)","NA","NA","NA","pleckstrin homology and RhoGEF domain containing G2 [Source:HGNC Symbol;Acc:HGNC:29515]",{"v":1.39830398423913,"d":"1.40"},{"v":0.429269677826087,"d":"0.43"},{"v":3.25740217972171,"d":"3.26"},{"v":1.70372185509445,"d":"1.70"},{"v":0.0338421487988274,"d":"0.03"},{"v":0.448643262685613,"d":"0.45"},"up","yes"]
["ENSG00000186026","ZNF284","ENST00000421176","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0005622(intracellular);GO:0003700(transcription factor activity, sequence-specific DNA binding)","NA","NA","NA","zinc finger protein 284 [Source:HGNC Symbol;Acc:HGNC:13078]",{"v":0.646672,"d":"0.65"},{"v":0.189002,"d":"0.19"},{"v":3.42150876710299,"d":"3.42"},{"v":1.77463264406558,"d":"1.77"},{"v":0.0338475725782768,"d":"0.03"},{"v":0.448643262685613,"d":"0.45"},"up","yes"]
["MSTRG.1671","ZNF32","ENST00000374433;ENST00000485351;ENST00000395797","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0005515(protein binding)","NA","NA","NA","zinc finger protein 32 [Source:HGNC Symbol;Acc:HGNC:13095]",{"v":3.88428624721448,"d":"3.88"},{"v":8.65657826740947,"d":"8.66"},{"v":0.448709192850269,"d":"0.45"},{"v":-1.15614735361071,"d":"-1.16"},{"v":0.0338586640947694,"d":"0.03"},{"v":0.448643262685613,"d":"0.45"},"down","yes"]
["MSTRG.13208","CDC40","ENST00000307731;ENST00000606893;ENST00000445340","GO:0003723(RNA binding);GO:0006397(mRNA processing);GO:0008380(RNA splicing);GO:0005634(nucleus);GO:0005515(protein binding);GO:0005681(spliceosomal complex);GO:0000398(mRNA splicing, via spliceosome);GO:0005654(nucleoplasm);GO:0006369(termination of RNA polymerase II transcription);GO:0006405(RNA export from nucleus);GO:0031124(mRNA 3'-end processing);GO:0006406(mRNA export from nucleus);GO:0071013(catalytic step 2 spliceosome);GO:0071013(catalytic step 2 spliceosome)","03040(Spliceosome);03040(Spliceosome)","K12816","NA","cell division cycle 40 [Source:HGNC Symbol;Acc:HGNC:17350]",{"v":6.13080351698621,"d":"6.13"},{"v":1.90336620181635,"d":"1.90"},{"v":3.22103203846726,"d":"3.22"},{"v":1.68752301076977,"d":"1.69"},{"v":0.0339003688774612,"d":"0.03"},{"v":0.448643262685613,"d":"0.45"},"up","yes"]
["ENSG00000188322","SBK1","ENST00000341901","GO:0005737(cytoplasm);GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0018105(peptidyl-serine phosphorylation);GO:0018107(peptidyl-threonine phosphorylation)","NA","NA","NA","SH3 domain binding kinase 1 [Source:HGNC Symbol;Acc:HGNC:17699]",{"v":3.706657,"d":"3.71"},{"v":1.144842,"d":"1.14"},{"v":3.23770179640509,"d":"3.24"},{"v":1.69497011452894,"d":"1.69"},{"v":0.03393729034411,"d":"0.03"},{"v":0.448643262685613,"d":"0.45"},"up","yes"]
["ENSG00000151458","ANKRD50","ENST00000504087","GO:0006810(transport);GO:0015031(protein transport);GO:0005515(protein binding);GO:0005768(endosome);GO:1990126(retrograde transport, endosome to plasma membrane)","NA","NA","NA","ankyrin repeat domain 50 [Source:HGNC Symbol;Acc:HGNC:29223]",{"v":1.266206,"d":"1.27"},{"v":0.390917,"d":"0.39"},{"v":3.23906609331393,"d":"3.24"},{"v":1.69557790670161,"d":"1.70"},{"v":0.0339582733058343,"d":"0.03"},{"v":0.448643262685613,"d":"0.45"},"up","yes"]
["ENSG00000197535","MYO5A","ENST00000399231;ENST00000356338;ENST00000553916;ENST00000561810;ENST00000556196;ENST00000465290;ENST00000399233;ENST00000469611;ENST00000568914;ENST00000399228;ENST00000399229","GO:0003723(RNA binding);GO:0006810(transport);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0015031(protein transport);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0003774(motor activity);GO:0016459(myosin complex);GO:0003779(actin binding);GO:0005829(cytosol);GO:0005783(endoplasmic reticulum);GO:0005764(lysosome);GO:0005777(peroxisome);GO:0016192(vesicle-mediated transport);GO:0005516(calmodulin binding);GO:0030426(growth cone);GO:0070062(extracellular exosome);GO:0005769(early endosome);GO:0005770(late endosome);GO:0055037(recycling endosome);GO:0001726(ruffle);GO:0043005(neuron projection);GO:0031982(vesicle);GO:0032869(cellular response to insulin stimulus);GO:0005884(actin filament);GO:0017137(Rab GTPase binding);GO:0030050(vesicle transport along actin filament);GO:0000146(microfilament motor activity);GO:0006892(post-Golgi vesicle-mediated transport);GO:0030048(actin filament-based movement);GO:0072659(protein localization to plasma membrane);GO:0032433(filopodium tip);GO:0032593(insulin-responsive compartment);GO:0005509(calcium ion binding);GO:0097718(disordered domain specific binding);GO:0006582(melanin metabolic process);GO:0006887(exocytosis);GO:0007268(chemical synaptic transmission);GO:0007601(visual perception);GO:0030073(insulin secretion);GO:0030318(melanocyte differentiation);GO:0031585(regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity);GO:0031987(locomotion involved in locomotory behavior);GO:0032252(secretory granule localization);GO:0032400(melanosome localization);GO:0032402(melanosome transport);GO:0042438(melanin biosynthetic process);GO:0042476(odontogenesis);GO:0042552(myelination);GO:0042759(long-chain fatty acid biosynthetic process);GO:0043473(pigmentation);GO:0048066(developmental pigmentation);GO:0048820(hair follicle maturation);GO:0050808(synapse organization);GO:0051643(endoplasmic reticulum localization);GO:0001750(photoreceptor outer segment);GO:0005794(Golgi apparatus);GO:0005882(intermediate filament);GO:0016461(unconventional myosin complex);GO:0030141(secretory granule);GO:0035371(microtubule plus-end);GO:0042470(melanosome);GO:0042641(actomyosin);GO:0043025(neuronal cell body);GO:0051015(actin filament binding);GO:0051015(actin filament binding)","NA","NA","NA","myosin VA [Source:HGNC Symbol;Acc:HGNC:7602]",{"v":5.17151374661226,"d":"5.17"},{"v":1.60958403395442,"d":"1.61"},{"v":3.21295045025198,"d":"3.21"},{"v":1.68389873190582,"d":"1.68"},{"v":0.0340275714853586,"d":"0.03"},{"v":0.449047940522124,"d":"0.45"},"up","yes"]
["MSTRG.8494","RPS7","ENST00000304921;ENST00000472966;ENST00000481006;ENST00000491937;ENST00000462576;ENST00000403564;ENST00000406376;ENST00000407445;ENST00000479123","GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0006412(translation);GO:0030529(intracellular ribonucleoprotein complex);GO:0005622(intracellular);GO:0003735(structural constituent of ribosome);GO:0005840(ribosome);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0022627(cytosolic small ribosomal subunit);GO:0005730(nucleolus);GO:0005925(focal adhesion);GO:0006364(rRNA processing);GO:0005813(centrosome);GO:0005815(microtubule organizing center);GO:0042274(ribosomal small subunit biogenesis);GO:0032040(small-subunit processome);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0019901(protein kinase binding);GO:0043234(protein complex);GO:0031012(extracellular matrix);GO:0002181(cytoplasmic translation);GO:0006413(translational initiation);GO:0030686(90S preribosome);GO:0000184(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay);GO:0019083(viral transcription);GO:0003730(mRNA 3'-UTR binding);GO:0048027(mRNA 5'-UTR binding);GO:0006614(SRP-dependent cotranslational protein targeting to membrane);GO:0010628(positive regulation of gene expression);GO:0050821(protein stabilization);GO:1990948(ubiquitin ligase inhibitor activity);GO:1904667(negative regulation of ubiquitin protein ligase activity);GO:2000059(negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process);GO:0008266(poly(U) RNA binding);GO:1902255(positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator);GO:1902255(positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator)","03010(Ribosome);03010(Ribosome)","K02993","NA","ribosomal protein S7 [Source:HGNC Symbol;Acc:HGNC:10440]",{"v":39.9737243689773,"d":"39.97"},{"v":88.1010922735089,"d":"88.10"},{"v":0.453725638779589,"d":"0.45"},{"v":-1.14010791019303,"d":"-1.14"},{"v":0.0343273489752022,"d":"0.03"},{"v":0.452489788477892,"d":"0.45"},"down","yes"]
["MSTRG.6935","RPS7P11","ENST00000484240","NA","NA","NA","NA","ribosomal protein S7 pseudogene 11 [Source:HGNC Symbol;Acc:HGNC:35841]",{"v":5.087154,"d":"5.09"},{"v":11.38076,"d":"11.38"},{"v":0.446995982693599,"d":"0.45"},{"v":-1.16166622941628,"d":"-1.16"},{"v":0.0345186759041641,"d":"0.03"},{"v":0.453987997413833,"d":"0.45"},"down","yes"]
["MSTRG.15260","UXT","MSTRG.15260.1;ENST00000335890;ENST00000333119;ENST00000485641;ENST00000460840;ENST00000376964","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0005815(microtubule organizing center);GO:0001106(RNA polymerase II transcription corepressor activity);GO:0003682(chromatin binding);GO:0008017(microtubule binding);GO:0000930(gamma-tubulin complex);GO:0005813(centrosome);GO:0048487(beta-tubulin binding);GO:0047497(mitochondrion transport along microtubule);GO:0007098(centrosome cycle);GO:0000226(microtubule cytoskeleton organization);GO:0000226(microtubule cytoskeleton organization)","NA","NA","NA","ubiquitously expressed prefoldin like chaperone [Source:HGNC Symbol;Acc:HGNC:12641]",{"v":11.8714302785315,"d":"11.87"},{"v":26.2351564565044,"d":"26.24"},{"v":0.45250083788192,"d":"0.45"},{"v":-1.1440076312949,"d":"-1.14"},{"v":0.0345191941545177,"d":"0.03"},{"v":0.453987997413833,"d":"0.45"},"down","yes"]
["MSTRG.10569","KIAA0930","ENST00000336156;ENST00000424508;ENST00000391627;ENST00000488038;ENST00000417906;ENST00000440039;ENST00000474515;ENST00000493003;ENST00000498418;ENST00000483374;ENST00000414854;ENST00000486640;ENST00000251993","NA","NA","NA","NA","KIAA0930 [Source:HGNC Symbol;Acc:HGNC:1314]",{"v":6.82165280127757,"d":"6.82"},{"v":2.12278440193632,"d":"2.12"},{"v":3.21354010094248,"d":"3.21"},{"v":1.68416347550815,"d":"1.68"},{"v":0.0346940840256656,"d":"0.03"},{"v":0.455271721203361,"d":"0.46"},"up","yes"]
["MSTRG.13558","KBTBD2","ENST00000304056;ENST00000621876;ENST00000485611;ENST00000423022;ENST00000477129","GO:0016567(protein ubiquitination);GO:0004842(ubiquitin-protein transferase activity);GO:0031463(Cul3-RING ubiquitin ligase complex);GO:0031463(Cul3-RING ubiquitin ligase complex)","NA","NA","NA","kelch repeat and BTB domain containing 2 [Source:HGNC Symbol;Acc:HGNC:21751]",{"v":4.38451594726288,"d":"4.38"},{"v":9.66378076779627,"d":"9.66"},{"v":0.453706065215584,"d":"0.45"},{"v":-1.14017014889067,"d":"-1.14"},{"v":0.0347097468360443,"d":"0.03"},{"v":0.455271721203361,"d":"0.46"},"down","yes"]
["MSTRG.4660","CCNK","MSTRG.4660.2;ENST00000389879;ENST00000556641;ENST00000555842;ENST00000557165;ENST00000553865;ENST00000553636","GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0006468(protein phosphorylation);GO:0051301(cell division);GO:0005515(protein binding);GO:0007049(cell cycle);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0004674(protein serine/threonine kinase activity);GO:0006366(transcription from RNA polymerase II promoter);GO:0006368(transcription elongation from RNA polymerase II promoter);GO:0042795(snRNA transcription from RNA polymerase II promoter);GO:0006974(cellular response to DNA damage stimulus);GO:0016538(cyclin-dependent protein serine/threonine kinase regulator activity);GO:0000079(regulation of cyclin-dependent protein serine/threonine kinase activity);GO:0045737(positive regulation of cyclin-dependent protein serine/threonine kinase activity);GO:0004693(cyclin-dependent protein serine/threonine kinase activity);GO:0008353(RNA polymerase II carboxy-terminal domain kinase activity);GO:0019901(protein kinase binding);GO:0044828(negative regulation by host of viral genome replication);GO:0071157(negative regulation of cell cycle arrest);GO:2001165(positive regulation of phosphorylation of RNA polymerase II C-terminal domain serine 2 residues);GO:0002944(cyclin K-CDK12 complex);GO:0002945(cyclin K-CDK13 complex);GO:0002945(cyclin K-CDK13 complex)","NA","NA","NA","cyclin K [Source:HGNC Symbol;Acc:HGNC:1596]",{"v":3.39622654756691,"d":"3.40"},{"v":1.05495272956204,"d":"1.05"},{"v":3.21931632801864,"d":"3.22"},{"v":1.68675434209735,"d":"1.69"},{"v":0.0347344135870299,"d":"0.03"},{"v":0.455271721203361,"d":"0.46"},"up","yes"]
["MSTRG.3123","KLRB1","ENST00000229402","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0030246(carbohydrate binding);GO:0005515(protein binding);GO:0050776(regulation of immune response);GO:0005886(plasma membrane);GO:0007166(cell surface receptor signaling pathway);GO:0004888(transmembrane signaling receptor activity)","05144(Malaria)","K06543","NA","killer cell lectin like receptor B1 [Source:HGNC Symbol;Acc:HGNC:6373]",{"v":34.721397,"d":"34.72"},{"v":76.365311,"d":"76.37"},{"v":0.454674989800015,"d":"0.45"},{"v":-1.13709244660841,"d":"-1.14"},{"v":0.0348119349637239,"d":"0.03"},{"v":0.455773394288305,"d":"0.46"},"down","yes"]
["MSTRG.5407","ZNF710","MSTRG.5407.3;ENST00000268154;ENST00000558883;MSTRG.5407.2;ENST00000559419;ENST00000559360","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0003677(DNA binding)","NA","NA","NA","zinc finger protein 710 [Source:HGNC Symbol;Acc:HGNC:25352]",{"v":7.02359522424812,"d":"7.02"},{"v":2.19232553120301,"d":"2.19"},{"v":3.20371912121737,"d":"3.20"},{"v":1.67974766828665,"d":"1.68"},{"v":0.0349042967723935,"d":"0.03"},{"v":0.456468016236267,"d":"0.46"},"up","yes"]
["MSTRG.995","RPS27","ENST00000493224;ENST00000368567;ENST00000392558;ENST00000477151","GO:0003723(RNA binding);GO:0005634(nucleus);GO:0006412(translation);GO:0046872(metal ion binding);GO:0003677(DNA binding);GO:0030529(intracellular ribonucleoprotein complex);GO:0005622(intracellular);GO:0003735(structural constituent of ribosome);GO:0005840(ribosome);GO:0008270(zinc ion binding);GO:0005515(protein binding);GO:0022627(cytosolic small ribosomal subunit);GO:0006364(rRNA processing);GO:0000028(ribosomal small subunit assembly);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0008283(cell proliferation);GO:0007062(sister chromatid cohesion);GO:0006413(translational initiation);GO:0000184(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay);GO:0019083(viral transcription);GO:0006614(SRP-dependent cotranslational protein targeting to membrane);GO:0006614(SRP-dependent cotranslational protein targeting to membrane)","03010(Ribosome);03010(Ribosome)","K02978","NA","ribosomal protein S27 [Source:HGNC Symbol;Acc:HGNC:10416]",{"v":474.509526019027,"d":"474.51"},{"v":1040.46855840592,"d":"1040.47"},{"v":0.456053690604561,"d":"0.46"},{"v":-1.13272441389827,"d":"-1.13"},{"v":0.0351857121300997,"d":"0.04"},{"v":0.459630680502641,"d":"0.46"},"down","yes"]
["MSTRG.11650","SULT1B1","ENST00000310613;ENST00000512870;ENST00000510821","GO:0005737(cytoplasm);GO:0016740(transferase activity);GO:0006629(lipid metabolic process);GO:0005829(cytosol);GO:0008202(steroid metabolic process);GO:0005515(protein binding);GO:0008146(sulfotransferase activity);GO:0006805(xenobiotic metabolic process);GO:0042403(thyroid hormone metabolic process);GO:0051923(sulfation);GO:0050427(3'-phosphoadenosine 5'-phosphosulfate metabolic process);GO:0030855(epithelial cell differentiation);GO:0004062(aryl sulfotransferase activity);GO:0006068(ethanol catabolic process);GO:0006576(cellular biogenic amine metabolic process);GO:0009812(flavonoid metabolic process);GO:0018958(phenol-containing compound metabolic process);GO:0018958(phenol-containing compound metabolic process)","NA","NA","NA","sulfotransferase family 1B member 1 [Source:HGNC Symbol;Acc:HGNC:17845]",{"v":14.9972537150625,"d":"15.00"},{"v":4.70875387656335,"d":"4.71"},{"v":3.18497294787642,"d":"3.18"},{"v":1.6712811187515,"d":"1.67"},{"v":0.0353739590137835,"d":"0.04"},{"v":0.461570546097828,"d":"0.46"},"up","yes"]
["ENSG00000188227","ZNF793","ENST00000588578;ENST00000587986;ENST00000587143;ENST00000445217;ENST00000589319;ENST00000627814;ENST00000586138;ENST00000586187","GO:0003676(nucleic acid binding);GO:0046872(metal ion binding);GO:0006355(regulation of transcription, DNA-templated);GO:0005622(intracellular);GO:0005634(nucleus);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0003677(DNA binding)","NA","NA","NA","zinc finger protein 793 [Source:HGNC Symbol;Acc:HGNC:33115]",{"v":0.263875042225369,"d":"0.26"},{"v":0.0781335325226951,"d":"0.08"},{"v":3.3772316917672,"d":"3.38"},{"v":1.75584115746131,"d":"1.76"},{"v":0.03563453812524,"d":"0.04"},{"v":0.462331595036743,"d":"0.46"},"up","yes"]
["MSTRG.14043","ZYX","MSTRG.14043.3;ENST00000322764;ENST00000457235;ENST00000354434;ENST00000477373;ENST00000468083;ENST00000497119;ENST00000392910;ENST00000436448;ENST00000446634","GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0005829(cytosol);GO:0007155(cell adhesion);GO:0005925(focal adhesion);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0030054(cell junction);GO:0007229(integrin-mediated signaling pathway);GO:0001725(stress fiber);GO:0016032(viral process);GO:0005887(integral component of plasma membrane);GO:0005886(plasma membrane);GO:0007165(signal transduction);GO:0007267(cell-cell signaling);GO:0007179(transforming growth factor beta receptor signaling pathway);GO:0007160(cell-matrix adhesion);GO:0043149(stress fiber assembly);GO:0005913(cell-cell adherens junction);GO:0050727(regulation of inflammatory response);GO:0050727(regulation of inflammatory response)","04510(Focal adhesion);04510(Focal adhesion)","K06273","NA","zyxin [Source:HGNC Symbol;Acc:HGNC:13200]",{"v":122.959672839747,"d":"122.96"},{"v":38.6863799431361,"d":"38.69"},{"v":3.17837112235576,"d":"3.18"},{"v":1.66828759074121,"d":"1.67"},{"v":0.0356539184326175,"d":"0.04"},{"v":0.462331595036743,"d":"0.46"},"up","yes"]
["ENSG00000138030","KHK","ENST00000260599;ENST00000469936;ENST00000464371","GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0005515(protein binding);GO:0005975(carbohydrate metabolic process);GO:0004454(ketohexokinase activity);GO:0006000(fructose metabolic process);GO:0009744(response to sucrose);GO:0009749(response to glucose);GO:0009750(response to fructose);GO:0010043(response to zinc ion);GO:0032868(response to insulin);GO:0046835(carbohydrate phosphorylation);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0061624(fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate);GO:0061624(fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate)","00051(Fructose and mannose metabolism);00051(Fructose and mannose metabolism)","K00846","EC:2.7.1.3","ketohexokinase [Source:HGNC Symbol;Acc:HGNC:6315]",{"v":0.261368158169935,"d":"0.26"},{"v":0.614864093137255,"d":"0.61"},{"v":0.425082812750281,"d":"0.43"},{"v":-1.23418416679998,"d":"-1.23"},{"v":0.0356828143679038,"d":"0.04"},{"v":0.462331595036743,"d":"0.46"},"down","yes"]
["MSTRG.3417","TARBP2","ENST00000266987;ENST00000394357;ENST00000552817;ENST00000546889;ENST00000547064;ENST00000547541;ENST00000551741;ENST00000549610;ENST00000549679;ENST00000548971;ENST00000550147;ENST00000546763;ENST00000549572;ENST00000550407;ENST00000551157;ENST00000552650;ENST00000552857;ENST00000547388","GO:0003723(RNA binding);GO:0003725(double-stranded RNA binding);GO:0016442(RISC complex);GO:0030422(production of siRNA involved in RNA interference);GO:0035197(siRNA binding);GO:0031054(pre-miRNA processing);GO:0035280(miRNA loading onto RISC involved in gene silencing by miRNA);GO:0046782(regulation of viral transcription);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005654(nucleoplasm);GO:0042803(protein homodimerization activity);GO:0005515(protein binding);GO:0016604(nuclear body);GO:0048471(perinuclear region of cytoplasm);GO:0031047(gene silencing by RNA);GO:0042802(identical protein binding);GO:0005829(cytosol);GO:0006417(regulation of translation);GO:0035087(siRNA loading onto RISC involved in RNA interference);GO:0019899(enzyme binding);GO:0006469(negative regulation of protein kinase activity);GO:0047485(protein N-terminus binding);GO:0045070(positive regulation of viral genome replication);GO:0070883(pre-miRNA binding);GO:0010586(miRNA metabolic process);GO:0035196(production of miRNAs involved in gene silencing by miRNA);GO:0070578(RISC-loading complex);GO:0036002(pre-mRNA binding);GO:0007286(spermatid development);GO:0007338(single fertilization);GO:0030423(targeting of mRNA for destruction involved in RNA interference);GO:0035264(multicellular organism growth);GO:0045727(positive regulation of translation);GO:0050689(negative regulation of defense response to virus by host);GO:0035068(micro-ribonucleoprotein complex);GO:0035068(micro-ribonucleoprotein complex)","NA","NA","NA","TARBP2, RISC loading complex RNA binding subunit [Source:HGNC Symbol;Acc:HGNC:11569]",{"v":0.975198674327628,"d":"0.98"},{"v":2.17596958264059,"d":"2.18"},{"v":0.448167420219267,"d":"0.45"},{"v":-1.15789031974834,"d":"-1.16"},{"v":0.0357466123515449,"d":"0.04"},{"v":0.462331595036743,"d":"0.46"},"down","yes"]
["MSTRG.7769","PRAM1","ENST00000423345;ENST00000594696;ENST00000599698;ENST00000600262","GO:0005515(protein binding);GO:0008289(lipid binding);GO:0019901(protein kinase binding);GO:0007165(signal transduction);GO:0043234(protein complex);GO:0007229(integrin-mediated signaling pathway);GO:0043313(regulation of neutrophil degranulation);GO:0043313(regulation of neutrophil degranulation)","NA","NA","NA","PML-RARA regulated adaptor molecule 1 [Source:HGNC Symbol;Acc:HGNC:30091]",{"v":9.14845030002658,"d":"9.15"},{"v":2.86578518389583,"d":"2.87"},{"v":3.19230148562284,"d":"3.19"},{"v":1.67459690822491,"d":"1.67"},{"v":0.035747875860039,"d":"0.04"},{"v":0.462331595036743,"d":"0.46"},"up","yes"]
["ENSG00000185436","IFNLR1","ENST00000374419;ENST00000374418;ENST00000327575;ENST00000327535","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005886(plasma membrane);GO:0051607(defense response to virus);GO:0005515(protein binding);GO:0008285(negative regulation of cell proliferation);GO:0019221(cytokine-mediated signaling pathway);GO:0002385(mucosal immune response);GO:0004896(cytokine receptor activity);GO:0032002(interleukin-28 receptor complex);GO:0050691(regulation of defense response to virus by host);GO:0034342(response to type III interferon);GO:0034342(response to type III interferon)","04630(Jak-STAT signaling pathway);04060(Cytokine-cytokine receptor interaction);04060(Cytokine-cytokine receptor interaction)","K05140","NA","interferon lambda receptor 1 [Source:HGNC Symbol;Acc:HGNC:18584]",{"v":0.768671733089579,"d":"0.77"},{"v":0.230704994515539,"d":"0.23"},{"v":3.33183828422841,"d":"3.33"},{"v":1.73631837903373,"d":"1.74"},{"v":0.0357677398331685,"d":"0.04"},{"v":0.462331595036743,"d":"0.46"},"up","yes"]
["ENSG00000198042","MAK16","ENST00000360128;ENST00000519089;ENST00000520763;ENST00000517567;ENST00000518389","GO:0003723(RNA binding);GO:0005634(nucleus);GO:0043231(intracellular membrane-bounded organelle);GO:0005730(nucleolus);GO:0030687(preribosome, large subunit precursor);GO:0000470(maturation of LSU-rRNA);GO:0000460(maturation of 5.8S rRNA);GO:0000460(maturation of 5.8S rRNA)","NA","NA","NA","MAK16 homolog [Source:HGNC Symbol;Acc:HGNC:13703]",{"v":0.926620315311597,"d":"0.93"},{"v":2.05770995026826,"d":"2.06"},{"v":0.4503162922407,"d":"0.45"},{"v":-1.15098942020636,"d":"-1.15"},{"v":0.0358119039372113,"d":"0.04"},{"v":0.462331595036743,"d":"0.46"},"down","yes"]
["ENSG00000063169","BICRA","ENST00000602258;ENST00000396720;ENST00000594866;ENST00000614245","GO:0005515(protein binding);GO:0005515(protein binding)","NA","NA","NA","BRD4 interacting chromatin remodeling complex associated protein [Source:HGNC Symbol;Acc:HGNC:4332]",{"v":0.974737742373785,"d":"0.97"},{"v":0.300329573997602,"d":"0.30"},{"v":3.24556030030385,"d":"3.25"},{"v":1.69846756071788,"d":"1.70"},{"v":0.0358706729229735,"d":"0.04"},{"v":0.462331595036743,"d":"0.46"},"up","yes"]
["MSTRG.12478","LARP1","MSTRG.12478.2;ENST00000522272;ENST00000518194;ENST00000518742;ENST00000518677;ENST00000519931;ENST00000518297;ENST00000336314;ENST00000518595;ENST00000524187;ENST00000517616;ENST00000521577;ENST00000519194;ENST00000518892;ENST00000524248","GO:0003723(RNA binding);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0006412(translation);GO:0006413(translational initiation);GO:0005515(protein binding);GO:0045727(positive regulation of translation);GO:0045296(cadherin binding);GO:0006417(regulation of translation);GO:0008283(cell proliferation);GO:0017148(negative regulation of translation);GO:0010494(cytoplasmic stress granule);GO:0016239(positive regulation of macroautophagy);GO:0003730(mRNA 3'-UTR binding);GO:0008190(eukaryotic initiation factor 4E binding);GO:0031369(translation initiation factor binding);GO:0048027(mRNA 5'-UTR binding);GO:0031931(TORC1 complex);GO:0045070(positive regulation of viral genome replication);GO:0005844(polysome);GO:0008494(translation activator activity);GO:0048255(mRNA stabilization);GO:0031929(TOR signaling);GO:0038202(TORC1 signaling);GO:0000339(RNA cap binding);GO:0072752(cellular response to rapamycin);GO:1990928(response to amino acid starvation);GO:1990928(response to amino acid starvation)","NA","NA","NA","La ribonucleoprotein domain family member 1 [Source:HGNC Symbol;Acc:HGNC:29531]",{"v":8.82558912802607,"d":"8.83"},{"v":2.7738000726257,"d":"2.77"},{"v":3.18176829509983,"d":"3.18"},{"v":1.66982877857226,"d":"1.67"},{"v":0.0359182088590494,"d":"0.04"},{"v":0.462331595036743,"d":"0.46"},"up","yes"]
["MSTRG.2719","RPS3;SNORD15A","ENST00000527446;ENST00000531188;ENST00000530170;ENST00000530164;ENST00000530721;ENST00000529173;ENST00000534440;ENST00000525690;ENST00000527273;ENST00000534555;ENST00000526608;ENST00000532872;ENST00000526248;ENST00000422465;ENST00000528847;ENST00000525933;ENST00000529285;ENST00000384214;ENST00000524851;ENST00000528439","GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0006412(translation);GO:0006413(translational initiation);GO:0005783(endoplasmic reticulum);GO:0005829(cytosol);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0005743(mitochondrial inner membrane);GO:0016829(lyase activity);GO:0003677(DNA binding);GO:0030529(intracellular ribonucleoprotein complex);GO:0003735(structural constituent of ribosome);GO:0005840(ribosome);GO:0051301(cell division);GO:0005739(mitochondrion);GO:0005886(plasma membrane);GO:0015935(small ribosomal subunit);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0006281(DNA repair);GO:0006974(cellular response to DNA damage stimulus);GO:0007049(cell cycle);GO:0006915(apoptotic process);GO:0022627(cytosolic small ribosomal subunit);GO:0005759(mitochondrial matrix);GO:0051536(iron-sulfur cluster binding);GO:0005730(nucleolus);GO:0005925(focal adhesion);GO:0008017(microtubule binding);GO:0005819(spindle);GO:0007059(chromosome segregation);GO:0003729(mRNA binding);GO:0003906(DNA-(apurinic or apyrimidinic site) lyase activity);GO:0005654(nucleoplasm);GO:0070062(extracellular exosome);GO:0019901(protein kinase binding);GO:0010628(positive regulation of gene expression);GO:0032587(ruffle membrane);GO:0006417(regulation of translation);GO:0031012(extracellular matrix);GO:0017148(negative regulation of translation);GO:0002181(cytoplasmic translation);GO:0042981(regulation of apoptotic process);GO:0019899(enzyme binding);GO:0008134(transcription factor binding);GO:0006979(response to oxidative stress);GO:0015631(tubulin binding);GO:0006364(rRNA processing);GO:0031397(negative regulation of protein ubiquitination);GO:0000184(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay);GO:0051225(spindle assembly);GO:0019083(viral transcription);GO:0045739(positive regulation of DNA repair);GO:0003684(damaged DNA binding);GO:0032357(oxidized purine DNA binding);GO:0019900(kinase binding);GO:0043507(positive regulation of JUN kinase activity);GO:0051018(protein kinase A binding);GO:1901224(positive regulation of NIK/NF-kappaB signaling);GO:0072686(mitotic spindle);GO:0051879(Hsp90 protein binding);GO:0097100(supercoiled DNA binding);GO:0006614(SRP-dependent cotranslational protein targeting to membrane);GO:0070301(cellular response to hydrogen peroxide);GO:0005844(polysome);GO:2001235(positive regulation of apoptotic signaling pathway);GO:0031334(positive regulation of protein complex assembly);GO:0031116(positive regulation of microtubule polymerization);GO:0000977(RNA polymerase II regulatory region sequence-specific DNA binding);GO:0004520(endodeoxyribonuclease activity);GO:0030544(Hsp70 protein binding);GO:0032358(oxidized pyrimidine DNA binding);GO:0032403(protein complex binding);GO:0044390(ubiquitin-like protein conjugating enzyme binding);GO:0070181(small ribosomal subunit rRNA binding);GO:0032079(positive regulation of endodeoxyribonuclease activity);GO:0032743(positive regulation of interleukin-2 production);GO:0042104(positive regulation of activated T cell proliferation);GO:0042769(DNA damage response, detection of DNA damage);GO:0045738(negative regulation of DNA repair);GO:0050862(positive regulation of T cell receptor signaling pathway);GO:0051092(positive regulation of NF-kappaB transcription factor activity);GO:0061481(response to TNF agonist);GO:0071356(cellular response to tumor necrosis factor);GO:1902231(positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage);GO:1902546(positive regulation of DNA N-glycosylase activity);GO:1905053(positive regulation of base-excision repair);GO:2001272(positive regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis);GO:0071159(NF-kappaB complex);GO:0071159(NF-kappaB complex)","03010(Ribosome);03010(Ribosome)","K02985","NA","ribosomal protein S3 [Source:HGNC Symbol;Acc:HGNC:10420];small nucleolar RNA, C/D box 15A [Source:HGNC Symbol;Acc:HGNC:10114]",{"v":52.422319955138,"d":"52.42"},{"v":114.515925428305,"d":"114.52"},{"v":0.457773185337074,"d":"0.46"},{"v":-1.12729513726731,"d":"-1.13"},{"v":0.035928763157655,"d":"0.04"},{"v":0.462331595036743,"d":"0.46"},"down","yes"]
["ENSG00000088827","SIGLEC1","ENST00000344754;ENST00000419548","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0030246(carbohydrate binding);GO:0007155(cell adhesion);GO:0005886(plasma membrane);GO:0005576(extracellular region);GO:0006954(inflammatory response);GO:0006897(endocytosis);GO:0007160(cell-matrix adhesion);GO:0016337(single organismal cell-cell adhesion);GO:0016337(single organismal cell-cell adhesion)","04514(Cell adhesion molecules (CAMs));04514(Cell adhesion molecules (CAMs))","K06548","NA","sialic acid binding Ig like lectin 1 [Source:HGNC Symbol;Acc:HGNC:11127]",{"v":0.631473025107786,"d":"0.63"},{"v":0.193580455237129,"d":"0.19"},{"v":3.26207015235218,"d":"3.26"},{"v":1.7057878082185,"d":"1.71"},{"v":0.0359322314571923,"d":"0.04"},{"v":0.462331595036743,"d":"0.46"},"up","yes"]
["ENSG00000104524","PYCR3","ENST00000495276;ENST00000220966;ENST00000482616","GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0008652(cellular amino acid biosynthetic process);GO:0004735(pyrroline-5-carboxylate reductase activity);GO:0006561(proline biosynthetic process);GO:0055129(L-proline biosynthetic process);GO:0042802(identical protein binding);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005515(protein binding);GO:0005515(protein binding)","00330(Arginine and proline metabolism);00330(Arginine and proline metabolism)","K00286","EC:1.5.1.2","pyrroline-5-carboxylate reductase 3 [Source:HGNC Symbol;Acc:HGNC:25846]",{"v":0.434118156596794,"d":"0.43"},{"v":0.985256630702836,"d":"0.99"},{"v":0.440614295878541,"d":"0.44"},{"v":-1.18241179036494,"d":"-1.18"},{"v":0.0359474382615113,"d":"0.04"},{"v":0.462331595036743,"d":"0.46"},"down","yes"]
["ENSG00000196663","TECPR2","ENST00000359520;ENST00000558678;ENST00000561228;ENST00000559124;ENST00000561099","GO:0005515(protein binding);GO:0006914(autophagy);GO:0006914(autophagy)","NA","NA","NA","tectonin beta-propeller repeat containing 2 [Source:HGNC Symbol;Acc:HGNC:19957]",{"v":9.74674260912191,"d":"9.75"},{"v":3.06541348060529,"d":"3.07"},{"v":3.17958496326484,"d":"3.18"},{"v":1.66883846031553,"d":"1.67"},{"v":0.0359498346954429,"d":"0.04"},{"v":0.462331595036743,"d":"0.46"},"up","yes"]
["MSTRG.15369","COX7B","ENST00000481445;ENST00000475465;ENST00000373335","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005743(mitochondrial inner membrane);GO:0005739(mitochondrion);GO:1902600(hydrogen ion transmembrane transport);GO:0004129(cytochrome-c oxidase activity);GO:0005746(mitochondrial respiratory chain);GO:0006123(mitochondrial electron transport, cytochrome c to oxygen);GO:0007417(central nervous system development);GO:0045277(respiratory chain complex IV);GO:0045277(respiratory chain complex IV)","00190(Oxidative phosphorylation);04260(Cardiac muscle contraction);05010(Alzheimer's disease);05012(Parkinson's disease);05016(Huntington's disease);04932(Non-alcoholic fatty liver disease (NAFLD));04932(Non-alcoholic fatty liver disease (NAFLD))","K02271","NA","cytochrome c oxidase subunit 7B [Source:HGNC Symbol;Acc:HGNC:2291]",{"v":6.97753872519841,"d":"6.98"},{"v":15.2707783250661,"d":"15.27"},{"v":0.456920962158503,"d":"0.46"},{"v":-1.12998346431648,"d":"-1.13"},{"v":0.0360470232215195,"d":"0.04"},{"v":0.462629927156935,"d":"0.46"},"down","yes"]
["MSTRG.13328","RAB32","ENST00000367495","GO:0016020(membrane);GO:0016192(vesicle-mediated transport);GO:0005525(GTP binding);GO:0000166(nucleotide binding);GO:0003924(GTPase activity);GO:0005739(mitochondrion);GO:0005515(protein binding);GO:0005794(Golgi apparatus);GO:0005802(trans-Golgi network);GO:0031982(vesicle);GO:0042470(melanosome);GO:0005741(mitochondrial outer membrane);GO:0031410(cytoplasmic vesicle);GO:0005783(endoplasmic reticulum);GO:0005829(cytosol);GO:0030670(phagocytic vesicle membrane);GO:0061024(membrane organization);GO:0030742(GTP-dependent protein binding);GO:0007005(mitochondrion organization);GO:0035646(endosome to melanosome transport);GO:0072657(protein localization to membrane);GO:0005769(early endosome);GO:0045335(phagocytic vesicle);GO:0019882(antigen processing and presentation);GO:0033162(melanosome membrane);GO:0090382(phagosome maturation);GO:0035650(AP-1 adaptor complex binding);GO:0035651(AP-3 adaptor complex binding);GO:0036461(BLOC-2 complex binding);GO:1903232(melanosome assembly);GO:0044233(ER-mitochondrion membrane contact site)","NA","NA","NA","RAB32, member RAS oncogene family [Source:HGNC Symbol;Acc:HGNC:9772]",{"v":10.14011,"d":"10.14"},{"v":22.230881,"d":"22.23"},{"v":0.456127222308464,"d":"0.46"},{"v":-1.13249182007111,"d":"-1.13"},{"v":0.0361056185154102,"d":"0.04"},{"v":0.462629927156935,"d":"0.46"},"down","yes"]
["MSTRG.1929","GBF1","ENST00000369983;ENST00000476019","GO:0006810(transport);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0015031(protein transport);GO:0005794(Golgi apparatus);GO:0043547(positive regulation of GTPase activity);GO:0005515(protein binding);GO:0005086(ARF guanyl-nucleotide exchange factor activity);GO:0032012(regulation of ARF protein signal transduction);GO:0005085(guanyl-nucleotide exchange factor activity);GO:0008289(lipid binding);GO:0030593(neutrophil chemotaxis);GO:0005829(cytosol);GO:0031252(cell leading edge);GO:0098586(cellular response to virus);GO:0080025(phosphatidylinositol-3,5-bisphosphate binding);GO:0006890(retrograde vesicle-mediated transport, Golgi to ER);GO:0005802(trans-Golgi network);GO:0016032(viral process);GO:0042147(retrograde transport, endosome to Golgi);GO:0005547(phosphatidylinositol-3,4,5-trisphosphate binding);GO:0007346(regulation of mitotic cell cycle);GO:0006892(post-Golgi vesicle-mediated transport);GO:0006895(Golgi to endosome transport);GO:0006888(ER to Golgi vesicle-mediated transport);GO:0000139(Golgi membrane);GO:0005811(lipid particle);GO:2000008(regulation of protein localization to cell surface);GO:0007030(Golgi organization);GO:0005793(endoplasmic reticulum-Golgi intermediate compartment);GO:0070973(protein localization to endoplasmic reticulum exit site);GO:0005801(cis-Golgi network);GO:0034067(protein localization to Golgi apparatus);GO:0090166(Golgi disassembly);GO:0048205(COPI coating of Golgi vesicle);GO:0097111(endoplasmic reticulum-Golgi intermediate compartment organization);GO:1903409(reactive oxygen species biosynthetic process);GO:0002263(cell activation involved in immune response);GO:0061162(establishment of monopolar cell polarity);GO:1903420(protein localization to endoplasmic reticulum tubular network);GO:0005739(mitochondrion);GO:0005777(peroxisome);GO:0005788(endoplasmic reticulum lumen);GO:0005795(Golgi stack);GO:0005795(Golgi stack)","04144(Endocytosis);04144(Endocytosis)","K18443","NA","golgi brefeldin A resistant guanine nucleotide exchange factor 1 [Source:HGNC Symbol;Acc:HGNC:4181]",{"v":7.72397095000753,"d":"7.72"},{"v":2.42876243020629,"d":"2.43"},{"v":3.18020851028706,"d":"3.18"},{"v":1.66912135887296,"d":"1.67"},{"v":0.0361134086484698,"d":"0.04"},{"v":0.462629927156935,"d":"0.46"},"up","yes"]
["MSTRG.7699","TICAM1","ENST00000248244","GO:0007165(signal transduction);GO:0004871(signal transducer activity);GO:0006915(apoptotic process);GO:0031410(cytoplasmic vesicle);GO:0002376(immune system process);GO:0045087(innate immune response);GO:0006954(inflammatory response);GO:0051607(defense response to virus);GO:0005515(protein binding);GO:0005829(cytosol);GO:0019901(protein kinase binding);GO:0010008(endosome membrane);GO:0005776(autophagosome);GO:0043123(positive regulation of I-kappaB kinase/NF-kappaB signaling);GO:0002756(MyD88-independent toll-like receptor signaling pathway);GO:0007249(I-kappaB kinase/NF-kappaB signaling);GO:0010628(positive regulation of gene expression);GO:0034128(negative regulation of MyD88-independent toll-like receptor signaling pathway);GO:0035666(TRIF-dependent toll-like receptor signaling pathway);GO:0070266(necroptotic process);GO:0097190(apoptotic signaling pathway);GO:0140052(-);GO:1900017(positive regulation of cytokine production involved in inflammatory response);GO:0043330(response to exogenous dsRNA);GO:0097342(ripoptosome);GO:0010508(positive regulation of autophagy);GO:0002281(macrophage activation involved in immune response);GO:0030890(positive regulation of B cell proliferation);GO:0031398(positive regulation of protein ubiquitination);GO:0031663(lipopolysaccharide-mediated signaling pathway);GO:0032092(positive regulation of protein binding);GO:0032481(positive regulation of type I interferon production);GO:0032496(response to lipopolysaccharide);GO:0032755(positive regulation of interleukin-6 production);GO:0032760(positive regulation of tumor necrosis factor production);GO:0032816(positive regulation of natural killer cell activation);GO:0043496(regulation of protein homodimerization activity);GO:0045080(positive regulation of chemokine biosynthetic process);GO:0045359(positive regulation of interferon-beta biosynthetic process);GO:0045429(positive regulation of nitric oxide biosynthetic process);GO:0050871(positive regulation of B cell activation);GO:0051092(positive regulation of NF-kappaB transcription factor activity);GO:0071222(cellular response to lipopolysaccharide)","04064(NF-kappa B signaling pathway);04217(Necroptosis);04620(Toll-like receptor signaling pathway);04621(NOD-like receptor signaling pathway);05133(Pertussis);05164(Influenza A);05161(Hepatitis B);05160(Hepatitis C);05168(Herpes simplex infection);05167(Kaposi's sarcoma-associated herpesvirus infection);05165(Human papillomavirus infection);05142(Chagas disease (American trypanosomiasis))","K05842","NA","toll like receptor adaptor molecule 1 [Source:HGNC Symbol;Acc:HGNC:18348]",{"v":5.302238,"d":"5.30"},{"v":1.656066,"d":"1.66"},{"v":3.20170693680083,"d":"3.20"},{"v":1.67884125908036,"d":"1.68"},{"v":0.0361323812909102,"d":"0.04"},{"v":0.462629927156935,"d":"0.46"},"up","yes"]
["ENSG00000197128","ZNF772","ENST00000427512;ENST00000425074;ENST00000600175;ENST00000356584;ENST00000343280","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0005622(intracellular);GO:0005515(protein binding);GO:0005515(protein binding)","NA","NA","NA","zinc finger protein 772 [Source:HGNC Symbol;Acc:HGNC:33106]",{"v":0.257193723261155,"d":"0.26"},{"v":0.583129046751969,"d":"0.58"},{"v":0.441057986553277,"d":"0.44"},{"v":-1.18095975335999,"d":"-1.18"},{"v":0.0363022037217158,"d":"0.04"},{"v":0.464150856193559,"d":"0.46"},"down","yes"]
["MSTRG.8670","CRIPT","ENST00000238892","GO:0005737(cytoplasm);GO:0005634(nucleus);GO:0005730(nucleolus);GO:0042995(cell projection);GO:0005515(protein binding);GO:0030054(cell junction);GO:0045202(synapse);GO:0030425(dendrite);GO:0008017(microtubule binding);GO:0014069(postsynaptic density);GO:0043197(dendritic spine);GO:0032403(protein complex binding);GO:0030165(PDZ domain binding);GO:0097110(scaffold protein binding);GO:0035372(protein localization to microtubule);GO:0045184(establishment of protein localization);GO:0043025(neuronal cell body);GO:0043198(dendritic shaft);GO:0031122(cytoplasmic microtubule organization);GO:1902897(regulation of postsynaptic density protein 95 clustering)","NA","NA","NA","CXXC repeat containing interactor of PDZ3 domain [Source:HGNC Symbol;Acc:HGNC:14312]",{"v":1.25541600585709,"d":"1.26"},{"v":2.78281604959,"d":"2.78"},{"v":0.451131509767616,"d":"0.45"},{"v":-1.14838003871731,"d":"-1.15"},{"v":0.0363311055093382,"d":"0.04"},{"v":0.464150856193559,"d":"0.46"},"down","yes"]
["MSTRG.11154","ZXDC","MSTRG.11154.1","NA","NA","NA","NA",null,{"v":4.484976,"d":"4.48"},{"v":1.324723,"d":"1.32"},{"v":3.38559532823088,"d":"3.39"},{"v":1.75940954179698,"d":"1.76"},{"v":0.0364158868247223,"d":"0.04"},{"v":0.464722740324725,"d":"0.46"},"up","yes"]
["MSTRG.15375","TAF9B","ENST00000341864;ENST00000480681","GO:0043066(negative regulation of apoptotic process);GO:0005634(nucleus);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0046982(protein heterodimerization activity);GO:0005515(protein binding);GO:0006352(DNA-templated transcription, initiation);GO:0005654(nucleoplasm);GO:0008134(transcription factor binding);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0016579(protein deubiquitination);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0006366(transcription from RNA polymerase II promoter);GO:0006368(transcription elongation from RNA polymerase II promoter);GO:0001075(transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly);GO:0006367(transcription initiation from RNA polymerase II promoter);GO:0051123(RNA polymerase II transcriptional preinitiation complex assembly);GO:1901796(regulation of signal transduction by p53 class mediator);GO:0033276(transcription factor TFTC complex);GO:0030307(positive regulation of cell growth);GO:0050821(protein stabilization);GO:0036459(thiol-dependent ubiquitinyl hydrolase activity);GO:1902166(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator);GO:0005669(transcription factor TFIID complex);GO:0003714(transcription corepressor activity);GO:0000124(SAGA complex);GO:0044212(transcription regulatory region DNA binding);GO:0004402(histone acetyltransferase activity);GO:0043966(histone H3 acetylation);GO:0043966(histone H3 acetylation)","03022(Basal transcription factors);05168(Herpes simplex infection);05168(Herpes simplex infection)","K03133","NA","TATA-box binding protein associated factor 9b [Source:HGNC Symbol;Acc:HGNC:17306]",{"v":2.86848144213544,"d":"2.87"},{"v":0.891486356503046,"d":"0.89"},{"v":3.2176391946001,"d":"3.22"},{"v":1.68600256057204,"d":"1.69"},{"v":0.0365295967205533,"d":"0.04"},{"v":0.465662136899875,"d":"0.47"},"up","yes"]
["MSTRG.412","AGO1","ENST00000373204;ENST00000373206;ENST00000635259","GO:0003676(nucleic acid binding);GO:0031047(gene silencing by RNA);GO:0000993(RNA polymerase II core binding);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0005737(cytoplasm);GO:0005634(nucleus);GO:0003723(RNA binding);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0030529(intracellular ribonucleoprotein complex);GO:0005515(protein binding);GO:0000932(P-body);GO:0000956(nuclear-transcribed mRNA catabolic process);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0006417(regulation of translation);GO:0038111(interleukin-7-mediated signaling pathway);GO:0048015(phosphatidylinositol-mediated signaling);GO:0045652(regulation of megakaryocyte differentiation);GO:0060964(regulation of gene silencing by miRNA);GO:0007223(Wnt signaling pathway, calcium modulating pathway);GO:0003725(double-stranded RNA binding);GO:0031054(pre-miRNA processing);GO:0035196(production of miRNAs involved in gene silencing by miRNA);GO:0070578(RISC-loading complex);GO:0005844(polysome);GO:0035278(miRNA mediated inhibition of translation);GO:0035068(micro-ribonucleoprotein complex);GO:0010501(RNA secondary structure unwinding);GO:0035280(miRNA loading onto RISC involved in gene silencing by miRNA);GO:0035194(posttranscriptional gene silencing by RNA);GO:0003727(single-stranded RNA binding);GO:0035198(miRNA binding);GO:0016442(RISC complex);GO:0001047(core promoter binding);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:0044212(transcription regulatory region DNA binding);GO:0010586(miRNA metabolic process);GO:0010628(positive regulation of gene expression);GO:1901224(positive regulation of NIK/NF-kappaB signaling);GO:1901224(positive regulation of NIK/NF-kappaB signaling)","NA","NA","NA","argonaute 1, RISC catalytic component [Source:HGNC Symbol;Acc:HGNC:3262]",{"v":4.24312214345384,"d":"4.24"},{"v":1.33733951260262,"d":"1.34"},{"v":3.17280847792811,"d":"3.17"},{"v":1.6657604376493,"d":"1.67"},{"v":0.0366122020049237,"d":"0.04"},{"v":0.466203401187696,"d":"0.47"},"up","yes"]
["ENSG00000181450","ZNF678","ENST00000440339;ENST00000343776;ENST00000397097;ENST00000465266;ENST00000608949","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0005622(intracellular);GO:0005622(intracellular)","NA","NA","NA","zinc finger protein 678 [Source:HGNC Symbol;Acc:HGNC:28652]",{"v":0.10533086517106,"d":"0.11"},{"v":0.244683518564218,"d":"0.24"},{"v":0.430477973298457,"d":"0.43"},{"v":-1.21598867521199,"d":"-1.22"},{"v":0.0366637491444344,"d":"0.04"},{"v":0.466348432436273,"d":"0.47"},"down","yes"]
["ENSG00000058866","DGKG","ENST00000265022;ENST00000480809;ENST00000490452;ENST00000466466;ENST00000482566;ENST00000472506","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0035556(intracellular signal transduction);GO:0005509(calcium ion binding);GO:0008152(metabolic process);GO:0003951(NAD+ kinase activity);GO:0004143(diacylglycerol kinase activity);GO:0007205(protein kinase C-activating G-protein coupled receptor signaling pathway);GO:0005886(plasma membrane);GO:0007165(signal transduction);GO:0030168(platelet activation);GO:0046834(lipid phosphorylation);GO:0046486(glycerolipid metabolic process);GO:0048666(neuron development);GO:0005622(intracellular);GO:0005622(intracellular)","00561(Glycerolipid metabolism);00564(Glycerophospholipid metabolism);04070(Phosphatidylinositol signaling system);04072(Phospholipase D signaling pathway);05231(Choline metabolism in cancer);05231(Choline metabolism in cancer)","K00901","EC:2.7.1.107","diacylglycerol kinase gamma [Source:HGNC Symbol;Acc:HGNC:2853]",{"v":0.910873374020769,"d":"0.91"},{"v":0.281818865093824,"d":"0.28"},{"v":3.23212349080151,"d":"3.23"},{"v":1.69248232066501,"d":"1.69"},{"v":0.0367057501484755,"d":"0.04"},{"v":0.466371856098737,"d":"0.47"},"up","yes"]
["MSTRG.8959","IGKV2-28","ENST00000482769","GO:0016020(membrane);GO:0005886(plasma membrane);GO:0005576(extracellular region);GO:0006508(proteolysis);GO:0002376(immune system process);GO:0002377(immunoglobulin production);GO:0006955(immune response);GO:0005615(extracellular space);GO:0003823(antigen binding);GO:0002250(adaptive immune response);GO:0004252(serine-type endopeptidase activity);GO:0006898(receptor-mediated endocytosis);GO:0006956(complement activation);GO:0006958(complement activation, classical pathway);GO:0030449(regulation of complement activation);GO:0038095(Fc-epsilon receptor signaling pathway);GO:0038096(Fc-gamma receptor signaling pathway involved in phagocytosis);GO:0050776(regulation of immune response);GO:0050900(leukocyte migration)","NA","NA","NA","immunoglobulin kappa variable 2-28 [Source:HGNC Symbol;Acc:HGNC:5783]",{"v":9.756445,"d":"9.76"},{"v":2.96102,"d":"2.96"},{"v":3.29496085808269,"d":"3.29"},{"v":1.72026132708905,"d":"1.72"},{"v":0.0368800316569462,"d":"0.04"},{"v":0.468074106701767,"d":"0.47"},"up","yes"]
["MSTRG.5474","NPRL3","MSTRG.5474.1;ENST00000399953;ENST00000621703;MSTRG.5474.4;ENST00000620134;MSTRG.5474.3;ENST00000622194;ENST00000422814;ENST00000610509;ENST00000483663;ENST00000456528;ENST00000473674;ENST00000611875;ENST00000464069;MSTRG.5474.5;ENST00000468260","GO:0016020(membrane);GO:0005765(lysosomal membrane);GO:0043547(positive regulation of GTPase activity);GO:0005096(GTPase activator activity);GO:0005764(lysosome);GO:0003674(molecular_function);GO:0008150(biological_process);GO:0005575(cellular_component);GO:2000785(regulation of autophagosome assembly);GO:0032007(negative regulation of TOR signaling);GO:0034198(cellular response to amino acid starvation);GO:1990130(GATOR1 complex);GO:0038202(TORC1 signaling);GO:0003281(ventricular septum development);GO:0035909(aorta morphogenesis);GO:0048738(cardiac muscle tissue development);GO:0060021(palate development);GO:0060021(palate development)","04150(mTOR signaling pathway);04150(mTOR signaling pathway)","K20406","NA","NPR3 like, GATOR1 complex subunit [Source:HGNC Symbol;Acc:HGNC:14124]",{"v":16.270449211259,"d":"16.27"},{"v":5.14786135938454,"d":"5.15"},{"v":3.1606230384581,"d":"3.16"},{"v":1.66020897798925,"d":"1.66"},{"v":0.0370390947489459,"d":"0.04"},{"v":0.468883567503837,"d":"0.47"},"up","yes"]
["ENSG00000169689","CENPX","ENST00000392359;ENST00000306704;ENST00000580435;ENST00000585091;ENST00000583767;ENST00000580090;ENST00000579520;ENST00000584347;ENST00000577379;ENST00000584600;ENST00000584514","GO:0006281(DNA repair);GO:0051382(kinetochore assembly);GO:0005634(nucleus);GO:0003677(DNA binding);GO:0051301(cell division);GO:0005694(chromosome);GO:0005515(protein binding);GO:0006974(cellular response to DNA damage stimulus);GO:0007049(cell cycle);GO:0043240(Fanconi anaemia nuclear complex);GO:0000775(chromosome, centromeric region);GO:0000776(kinetochore);GO:0000777(condensed chromosome kinetochore);GO:0005654(nucleoplasm);GO:0003690(double-stranded DNA binding);GO:0000712(resolution of meiotic recombination intermediates);GO:0031297(replication fork processing);GO:0031398(positive regulation of protein ubiquitination);GO:0034080(CENP-A containing nucleosome assembly);GO:0036297(interstrand cross-link repair);GO:0071821(FANCM-MHF complex);GO:0071821(FANCM-MHF complex)","03460(Fanconi anemia pathway);03460(Fanconi anemia pathway)","K15360","NA","centromere protein X [Source:HGNC Symbol;Acc:HGNC:11422]",{"v":2.62206653559765,"d":"2.62"},{"v":5.79331179751796,"d":"5.79"},{"v":0.452602350303505,"d":"0.45"},{"v":-1.14368401854061,"d":"-1.14"},{"v":0.0370573417934043,"d":"0.04"},{"v":0.468883567503837,"d":"0.47"},"down","yes"]
["MSTRG.1330","PIK3C2B","ENST00000367187;ENST00000367184;ENST00000496872;ENST00000429009;ENST00000415899;ENST00000462752","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0005783(endoplasmic reticulum);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0035091(phosphatidylinositol binding);GO:0046854(phosphatidylinositol phosphorylation);GO:0048015(phosphatidylinositol-mediated signaling);GO:0008150(biological_process);GO:0043231(intracellular membrane-bounded organelle);GO:0001727(lipid kinase activity);GO:0009267(cellular response to starvation);GO:0016236(macroautophagy);GO:0036092(phosphatidylinositol-3-phosphate biosynthetic process);GO:0043491(protein kinase B signaling);GO:1905037(autophagosome organization);GO:0030139(endocytic vesicle);GO:0005942(phosphatidylinositol 3-kinase complex);GO:0016303(1-phosphatidylinositol-3-kinase activity);GO:0035005(1-phosphatidylinositol-4-phosphate 3-kinase activity);GO:0006661(phosphatidylinositol biosynthetic process);GO:0014065(phosphatidylinositol 3-kinase signaling);GO:0016477(cell migration);GO:0005622(intracellular);GO:0005622(intracellular)","00562(Inositol phosphate metabolism);04070(Phosphatidylinositol signaling system);04070(Phosphatidylinositol signaling system)","K00923","EC:2.7.1.154","phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 beta [Source:HGNC Symbol;Acc:HGNC:8972]",{"v":1.8941222903123,"d":"1.89"},{"v":0.595374965795624,"d":"0.60"},{"v":3.18139390993893,"d":"3.18"},{"v":1.66965901278656,"d":"1.67"},{"v":0.0370987044806686,"d":"0.04"},{"v":0.468883567503837,"d":"0.47"},"up","yes"]
["MSTRG.11458","CEP19","ENST00000409690","GO:0005737(cytoplasm);GO:0005813(centrosome);GO:0005856(cytoskeleton);GO:0042995(cell projection);GO:0005515(protein binding);GO:0000922(spindle pole);GO:0005814(centriole);GO:0036064(ciliary basal body)","NA","NA","NA","centrosomal protein 19 [Source:HGNC Symbol;Acc:HGNC:28209]",{"v":2.39705,"d":"2.40"},{"v":5.245814,"d":"5.25"},{"v":0.456945290092253,"d":"0.46"},{"v":-1.12990665266205,"d":"-1.13"},{"v":0.0372462232415751,"d":"0.04"},{"v":0.468883567503837,"d":"0.47"},"down","yes"]
["MSTRG.14030","MGAM","ENST00000620571;ENST00000475668;ENST00000549489;MSTRG.14030.3;ENST00000497673;ENST00000495045;ENST00000490593;MSTRG.14030.4;ENST00000485078","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0030246(carbohydrate binding);GO:0016787(hydrolase activity);GO:0003824(catalytic activity);GO:0005975(carbohydrate metabolic process);GO:0005886(plasma membrane);GO:0008152(metabolic process);GO:0004553(hydrolase activity, hydrolyzing O-glycosyl compounds);GO:0016798(hydrolase activity, acting on glycosyl bonds);GO:0070062(extracellular exosome);GO:0043312(neutrophil degranulation);GO:0070821(tertiary granule membrane);GO:0016324(apical plasma membrane);GO:0101003(ficolin-1-rich granule membrane);GO:0004339(glucan 1,4-alpha-glucosidase activity);GO:0004558(alpha-1,4-glucosidase activity);GO:0016160(amylase activity);GO:0032450(maltose alpha-glucosidase activity);GO:0000023(maltose metabolic process);GO:0005983(starch catabolic process);GO:0044245(polysaccharide digestion);GO:0044245(polysaccharide digestion)","00052(Galactose metabolism);00500(Starch and sucrose metabolism);04973(Carbohydrate digestion and absorption);04973(Carbohydrate digestion and absorption)","K12047","EC:3.2.1.20;EC:3.2.1.3","maltase-glucoamylase [Source:HGNC Symbol;Acc:HGNC:7043]",{"v":26.7786354016725,"d":"26.78"},{"v":8.49735793447896,"d":"8.50"},{"v":3.15140725013069,"d":"3.15"},{"v":1.65599620303179,"d":"1.66"},{"v":0.0372726447887242,"d":"0.04"},{"v":0.468883567503837,"d":"0.47"},"up","yes"]
["ENSG00000213949","ITGA1","ENST00000282588;ENST00000504086;ENST00000506275;ENST00000504669","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0046872(metal ion binding);GO:0007155(cell adhesion);GO:0007229(integrin-mediated signaling pathway);GO:0008305(integrin complex);GO:0005925(focal adhesion);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0070062(extracellular exosome);GO:0008285(negative regulation of cell proliferation);GO:0019903(protein phosphatase binding);GO:0009986(cell surface);GO:0030198(extracellular matrix organization);GO:0007160(cell-matrix adhesion);GO:0006936(muscle contraction);GO:0005518(collagen binding);GO:0098639(collagen binding involved in cell-matrix adhesion);GO:0034665(integrin alpha1-beta1 complex);GO:0032516(positive regulation of phosphoprotein phosphatase activity);GO:0042059(negative regulation of epidermal growth factor receptor signaling pathway);GO:0005102(receptor binding);GO:0000187(activation of MAPK activity);GO:0030593(neutrophil chemotaxis);GO:0042311(vasodilation);GO:0043525(positive regulation of neuron apoptotic process);GO:0045123(cellular extravasation);GO:0048812(neuron projection morphogenesis);GO:0060326(cell chemotaxis);GO:0001669(acrosomal vesicle);GO:0009897(external side of plasma membrane);GO:0043005(neuron projection);GO:0043204(perikaryon);GO:0045121(membrane raft);GO:0045178(basal part of cell);GO:0045178(basal part of cell)","04151(PI3K-Akt signaling pathway);04512(ECM-receptor interaction);04510(Focal adhesion);04810(Regulation of actin cytoskeleton);04640(Hematopoietic cell lineage);05410(Hypertrophic cardiomyopathy (HCM));05412(Arrhythmogenic right ventricular cardiomyopathy (ARVC));05414(Dilated cardiomyopathy (DCM));05165(Human papillomavirus infection);05165(Human papillomavirus infection)","K06480","NA","integrin subunit alpha 1 [Source:HGNC Symbol;Acc:HGNC:6134]",{"v":0.24174774970376,"d":"0.24"},{"v":0.0732765978670688,"d":"0.07"},{"v":3.29911263268957,"d":"3.30"},{"v":1.72207803278276,"d":"1.72"},{"v":0.0373320320041486,"d":"0.04"},{"v":0.468883567503837,"d":"0.47"},"up","yes"]
["MSTRG.14972","SH2D3C","ENST00000314830;ENST00000468969;ENST00000464239;ENST00000429553;ENST00000414380;ENST00000373277;ENST00000471939;ENST00000420366;ENST00000484160;ENST00000629203;ENST00000488685;ENST00000373276;ENST00000440630","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0007264(small GTPase mediated signal transduction);GO:0009967(positive regulation of signal transduction);GO:0043547(positive regulation of GTPase activity);GO:0005515(protein binding);GO:0005085(guanyl-nucleotide exchange factor activity);GO:0005070(SH3/SH2 adaptor activity);GO:0007254(JNK cascade);GO:0007254(JNK cascade)","NA","NA","NA","SH2 domain containing 3C [Source:HGNC Symbol;Acc:HGNC:16884]",{"v":20.3406572620734,"d":"20.34"},{"v":6.43703871989697,"d":"6.44"},{"v":3.15994017547233,"d":"3.16"},{"v":1.65989724531175,"d":"1.66"},{"v":0.0373808194637822,"d":"0.04"},{"v":0.468883567503837,"d":"0.47"},"up","yes"]
["MSTRG.14532","MRPL13","ENST00000306185;ENST00000520677;ENST00000518918;ENST00000518696;ENST00000613356;ENST00000522717","GO:0003735(structural constituent of ribosome);GO:0006412(translation);GO:0005840(ribosome);GO:0003723(RNA binding);GO:0030529(intracellular ribonucleoprotein complex);GO:0005739(mitochondrion);GO:0005515(protein binding);GO:0003729(mRNA binding);GO:0005743(mitochondrial inner membrane);GO:0070125(mitochondrial translational elongation);GO:0070126(mitochondrial translational termination);GO:0005761(mitochondrial ribosome);GO:0005762(mitochondrial large ribosomal subunit);GO:0005762(mitochondrial large ribosomal subunit)","03010(Ribosome);03010(Ribosome)","K02871","NA","mitochondrial ribosomal protein L13 [Source:HGNC Symbol;Acc:HGNC:14278]",{"v":0.935906065573771,"d":"0.94"},{"v":2.06346021691613,"d":"2.06"},{"v":0.453561477900696,"d":"0.45"},{"v":-1.14062998106589,"d":"-1.14"},{"v":0.0373903492042562,"d":"0.04"},{"v":0.468883567503837,"d":"0.47"},"down","yes"]
["MSTRG.12560","ARL10","ENST00000310389;ENST00000507151;ENST00000503175;ENST00000514533","GO:0005525(GTP binding);GO:0007264(small GTPase mediated signal transduction);GO:0000166(nucleotide binding);GO:0005622(intracellular);GO:0005622(intracellular)","NA","NA","NA","ADP ribosylation factor like GTPase 10 [Source:HGNC Symbol;Acc:HGNC:22042]",{"v":0.87365661864037,"d":"0.87"},{"v":0.273251600488699,"d":"0.27"},{"v":3.19726075557425,"d":"3.20"},{"v":1.67683640925235,"d":"1.68"},{"v":0.0374038511061273,"d":"0.04"},{"v":0.468883567503837,"d":"0.47"},"up","yes"]
["MSTRG.604","JAK1","ENST00000342505;ENST00000467764;ENST00000481702;ENST00000494904;ENST00000471473;ENST00000465376","GO:0005737(cytoplasm);GO:1903672(positive regulation of sprouting angiogenesis);GO:0005634(nucleus);GO:0016020(membrane);GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0035556(intracellular signal transduction);GO:0004713(protein tyrosine kinase activity);GO:0043547(positive regulation of GTPase activity);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0004715(non-membrane spanning protein tyrosine kinase activity);GO:0005925(focal adhesion);GO:0045087(innate immune response);GO:0005829(cytosol);GO:0000165(MAPK cascade);GO:0012505(endomembrane system);GO:0031625(ubiquitin protein ligase binding);GO:0030154(cell differentiation);GO:0035722(interleukin-12-mediated signaling pathway);GO:0019903(protein phosphatase binding);GO:0042127(regulation of cell proliferation);GO:0038111(interleukin-7-mediated signaling pathway);GO:0016477(cell migration);GO:0005088(Ras guanyl-nucleotide exchange factor activity);GO:0060333(interferon-gamma-mediated signaling pathway);GO:0060334(regulation of interferon-gamma-mediated signaling pathway);GO:0060337(type I interferon signaling pathway);GO:0005102(receptor binding);GO:0005131(growth hormone receptor binding);GO:0038083(peptidyl-tyrosine autophosphorylation);GO:0046677(response to antibiotic);GO:0031234(extrinsic component of cytoplasmic side of plasma membrane);GO:0007169(transmembrane receptor protein tyrosine kinase signaling pathway);GO:0060338(regulation of type I interferon-mediated signaling pathway);GO:0031730(CCR5 chemokine receptor binding);GO:0038110(interleukin-2-mediated signaling pathway);GO:0046777(protein autophosphorylation);GO:0046777(protein autophosphorylation)","04630(Jak-STAT signaling pathway);04151(PI3K-Akt signaling pathway);04217(Necroptosis);04550(Signaling pathways regulating pluripotency of stem cells);04621(NOD-like receptor signaling pathway);04658(Th1 and Th2 cell differentiation);04659(Th17 cell differentiation);04380(Osteoclast differentiation);05200(Pathways in cancer);05203(Viral carcinogenesis);05212(Pancreatic cancer);05152(Tuberculosis);05166(HTLV-I infection);05162(Measles);05164(Influenza A);05161(Hepatitis B);05160(Hepatitis C);05168(Herpes simplex infection);05167(Kaposi's sarcoma-associated herpesvirus infection);05169(Epstein-Barr virus infection);05165(Human papillomavirus infection);05145(Toxoplasmosis);05140(Leishmaniasis);01521(EGFR tyrosine kinase inhibitor resistance);01521(EGFR tyrosine kinase inhibitor resistance)","K11217","EC:2.7.10.2","Janus kinase 1 [Source:HGNC Symbol;Acc:HGNC:6190]",{"v":76.5523889658065,"d":"76.55"},{"v":24.3167192947602,"d":"24.32"},{"v":3.14813803777807,"d":"3.15"},{"v":1.65449880070937,"d":"1.65"},{"v":0.0374143353269628,"d":"0.04"},{"v":0.468883567503837,"d":"0.47"},"up","yes"]
["MSTRG.13363","AL590867.2","ENST00000492974","NA","NA","NA","NA",null,{"v":90.220871,"d":"90.22"},{"v":195.743713,"d":"195.74"},{"v":0.46091325037857,"d":"0.46"},{"v":-1.11743285188047,"d":"-1.12"},{"v":0.0374188057401627,"d":"0.04"},{"v":0.468883567503837,"d":"0.47"},"down","yes"]
["ENSG00000169598","DFFB","ENST00000378209;ENST00000339350;ENST00000491998;ENST00000477548;ENST00000468793;ENST00000461150;ENST00000338895;ENST00000481945","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005730(nucleolus);GO:0016787(hydrolase activity);GO:0005622(intracellular);GO:0000790(nuclear chromatin);GO:0005829(cytosol);GO:0006915(apoptotic process);GO:0005515(protein binding);GO:0004518(nuclease activity);GO:0005654(nucleoplasm);GO:0006309(apoptotic DNA fragmentation);GO:0019899(enzyme binding);GO:0019904(protein domain specific binding);GO:0051260(protein homooligomerization);GO:0042802(identical protein binding);GO:0004536(deoxyribonuclease activity);GO:0097718(disordered domain specific binding);GO:0006308(DNA catabolic process);GO:0030263(apoptotic chromosome condensation);GO:0003677(DNA binding);GO:0003677(DNA binding)","04210(Apoptosis);04210(Apoptosis)","K02311","EC:3.-.-.-","DNA fragmentation factor subunit beta [Source:HGNC Symbol;Acc:HGNC:2773]",{"v":1.63825494108527,"d":"1.64"},{"v":0.504959613436693,"d":"0.50"},{"v":3.24432865023701,"d":"3.24"},{"v":1.69791997185205,"d":"1.70"},{"v":0.0374369367862688,"d":"0.04"},{"v":0.468883567503837,"d":"0.47"},"up","yes"]
["MSTRG.4692","RCOR1","ENST00000262241;ENST00000559597;ENST00000560472;ENST00000558495","GO:0005634(nucleus);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0016569(covalent chromatin modification);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0005654(nucleoplasm);GO:0008134(transcription factor binding);GO:0003714(transcription corepressor activity);GO:0005667(transcription factor complex);GO:0016032(viral process);GO:0044212(transcription regulatory region DNA binding);GO:0045892(negative regulation of transcription, DNA-templated);GO:0004407(histone deacetylase activity);GO:0001078(transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0007596(blood coagulation);GO:0017053(transcriptional repressor complex);GO:1990391(DNA repair complex);GO:0070933(histone H4 deacetylation);GO:0070933(histone H4 deacetylation)","05016(Huntington's disease);05016(Huntington's disease)","K11829","NA","REST corepressor 1 [Source:HGNC Symbol;Acc:HGNC:17441]",{"v":12.6918235931957,"d":"12.69"},{"v":4.02638145936795,"d":"4.03"},{"v":3.15216621208762,"d":"3.15"},{"v":1.65634360936039,"d":"1.66"},{"v":0.0374686946218514,"d":"0.04"},{"v":0.468883567503837,"d":"0.47"},"up","yes"]
["MSTRG.1007","HAX1","ENST00000531435;ENST00000328703;ENST00000457918;ENST00000492550;ENST00000435087;ENST00000459914;ENST00000477780;ENST00000483970;ENST00000447768;ENST00000532105;ENST00000471326","GO:0051897(positive regulation of protein kinase B signaling);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0014068(positive regulation of phosphatidylinositol 3-kinase signaling);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005739(mitochondrion);GO:0005783(endoplasmic reticulum);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0005741(mitochondrial outer membrane);GO:0031410(cytoplasmic vesicle);GO:0000932(P-body);GO:0015629(actin cytoskeleton);GO:0016529(sarcoplasmic reticulum);GO:0030027(lamellipodium);GO:0005758(mitochondrial intermembrane space);GO:0005938(cell cortex);GO:0019966(interleukin-1 binding);GO:0047485(protein N-terminus binding);GO:0030833(regulation of actin filament polymerization);GO:0030854(positive regulation of granulocyte differentiation);GO:0033138(positive regulation of peptidyl-serine phosphorylation);GO:0042981(regulation of apoptotic process);GO:0043066(negative regulation of apoptotic process);GO:0050731(positive regulation of peptidyl-tyrosine phosphorylation);GO:0071345(cellular response to cytokine stimulus);GO:1903146(regulation of mitophagy);GO:1903214(regulation of protein targeting to mitochondrion);GO:2000251(positive regulation of actin cytoskeleton reorganization);GO:0005635(nuclear envelope);GO:0005667(transcription factor complex);GO:0031965(nuclear membrane);GO:0031965(nuclear membrane)","NA","NA","NA","HCLS1 associated protein X-1 [Source:HGNC Symbol;Acc:HGNC:16915]",{"v":9.47188665382831,"d":"9.47"},{"v":20.5642660547564,"d":"20.56"},{"v":0.460599305057013,"d":"0.46"},{"v":-1.11841586046429,"d":"-1.12"},{"v":0.0375908409935767,"d":"0.04"},{"v":0.46990574430399,"d":"0.47"},"down","yes"]
["MSTRG.989","GATAD2B","ENST00000368655;ENST00000637918;ENST00000634564;ENST00000636014;ENST00000634645;ENST00000634544;ENST00000637331;ENST00000634401;ENST00000634791","GO:0005634(nucleus);GO:0016607(nuclear speck);GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0005654(nucleoplasm);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0000790(nuclear chromatin);GO:0043565(sequence-specific DNA binding);GO:0005515(protein binding);GO:0043234(protein complex);GO:0031492(nucleosomal DNA binding);GO:0043044(ATP-dependent chromatin remodeling);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:0000980(RNA polymerase II distal enhancer sequence-specific DNA binding);GO:0000980(RNA polymerase II distal enhancer sequence-specific DNA binding)","NA","NA","NA","GATA zinc finger domain containing 2B [Source:HGNC Symbol;Acc:HGNC:30778]",{"v":6.50952958505461,"d":"6.51"},{"v":2.0672722822537,"d":"2.07"},{"v":3.14884964159537,"d":"3.15"},{"v":1.65482487004758,"d":"1.65"},{"v":0.0376979958748076,"d":"0.04"},{"v":0.470515079329758,"d":"0.47"},"up","yes"]
["MSTRG.36","AL669831.1;AL669831.3","ENST00000506640;ENST00000440196;ENST00000419394;ENST00000636676;ENST00000641296;ENST00000414688;ENST00000635509;ENST00000447954;MSTRG.36.16","NA","NA","NA","NA",null,{"v":4.32864452380196,"d":"4.33"},{"v":1.37221412771199,"d":"1.37"},{"v":3.15449639847352,"d":"3.15"},{"v":1.65740970364951,"d":"1.66"},{"v":0.0377206181741156,"d":"0.04"},{"v":0.470515079329758,"d":"0.47"},"up","yes"]
["MSTRG.6343","AC087500.1","MSTRG.6343.1","NA","NA","NA","NA",null,{"v":5.308182,"d":"5.31"},{"v":1.662639,"d":"1.66"},{"v":3.1926244963579,"d":"3.19"},{"v":1.67474287890252,"d":"1.67"},{"v":0.0378077857643875,"d":"0.04"},{"v":0.471096369186515,"d":"0.47"},"up","yes"]
["MSTRG.13649","CHCHD2","ENST00000395422;ENST00000473095","GO:0005634(nucleus);GO:0006351(transcription, DNA-templated);GO:0005739(mitochondrion);GO:0005515(protein binding);GO:0005758(mitochondrial intermembrane space);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0043565(sequence-specific DNA binding);GO:0008134(transcription factor binding);GO:1900037(regulation of cellular response to hypoxia);GO:0007005(mitochondrion organization);GO:0007005(mitochondrion organization)","NA","NA","NA","coiled-coil-helix-coiled-coil-helix domain containing 2 [Source:HGNC Symbol;Acc:HGNC:21645]",{"v":39.6246171166078,"d":"39.62"},{"v":85.6989869717314,"d":"85.70"},{"v":0.462369725906776,"d":"0.46"},{"v":-1.11288115577283,"d":"-1.11"},{"v":0.03795960738113,"d":"0.04"},{"v":0.471984281412782,"d":"0.47"},"down","yes"]
["ENSG00000198860","TSEN15","ENST00000361641;ENST00000462677;ENST00000457455;ENST00000533373;ENST00000367518;ENST00000485209;ENST00000423085","GO:0006397(mRNA processing);GO:0005634(nucleus);GO:0008033(tRNA processing);GO:0090305(nucleic acid phosphodiester bond hydrolysis);GO:0000213(tRNA-intron endonuclease activity);GO:0004519(endonuclease activity);GO:0006388(tRNA splicing, via endonucleolytic cleavage and ligation);GO:0090501(RNA phosphodiester bond hydrolysis);GO:0090502(RNA phosphodiester bond hydrolysis, endonucleolytic);GO:0005730(nucleolus);GO:0005654(nucleoplasm);GO:0005654(nucleoplasm)","NA","NA","NA","tRNA splicing endonuclease subunit 15 [Source:HGNC Symbol;Acc:HGNC:16791]",{"v":2.71038850347933,"d":"2.71"},{"v":5.92398743225542,"d":"5.92"},{"v":0.457527726801306,"d":"0.46"},{"v":-1.12806891956357,"d":"-1.13"},{"v":0.0380399383042169,"d":"0.04"},{"v":0.471984281412782,"d":"0.47"},"down","yes"]
["MSTRG.14645","RPL8;MIR6850","ENST00000394920;ENST00000531975;ENST00000262584;ENST00000527914;ENST00000528957;ENST00000533397;ENST00000529920;ENST00000525232;ENST00000526668;ENST00000532702;ENST00000531767;ENST00000529163;ENST00000528296;ENST00000534781;ENST00000612162","GO:0003723(RNA binding);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0006412(translation);GO:0030529(intracellular ribonucleoprotein complex);GO:0005622(intracellular);GO:0003735(structural constituent of ribosome);GO:0005840(ribosome);GO:0015934(large ribosomal subunit);GO:0005925(focal adhesion);GO:0005829(cytosol);GO:0019843(rRNA binding);GO:0002181(cytoplasmic translation);GO:0006413(translational initiation);GO:0006364(rRNA processing);GO:0000184(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay);GO:0019083(viral transcription);GO:0006614(SRP-dependent cotranslational protein targeting to membrane);GO:0022625(cytosolic large ribosomal subunit);GO:1990932(5.8S rRNA binding);GO:1990090(cellular response to nerve growth factor stimulus);GO:1990090(cellular response to nerve growth factor stimulus)","03010(Ribosome);03010(Ribosome)","K02938","NA","ribosomal protein L8 [Source:HGNC Symbol;Acc:HGNC:10368];microRNA 6850 [Source:HGNC Symbol;Acc:HGNC:50093]",{"v":203.793458507987,"d":"203.79"},{"v":440.131327748973,"d":"440.13"},{"v":0.463028749964873,"d":"0.46"},{"v":-1.11082632009725,"d":"-1.11"},{"v":0.0380548510029147,"d":"0.04"},{"v":0.471984281412782,"d":"0.47"},"down","yes"]
["ENSG00000184545","DUSP8","ENST00000397374;ENST00000528778;ENST00000331588","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016787(hydrolase activity);GO:0004725(protein tyrosine phosphatase activity);GO:0008138(protein tyrosine/serine/threonine phosphatase activity);GO:0016791(phosphatase activity);GO:0006470(protein dephosphorylation);GO:0016311(dephosphorylation);GO:0035335(peptidyl-tyrosine dephosphorylation);GO:0004721(phosphoprotein phosphatase activity);GO:0017017(MAP kinase tyrosine/serine/threonine phosphatase activity);GO:0000188(inactivation of MAPK activity);GO:0000188(inactivation of MAPK activity)","04010(MAPK signaling pathway);04010(MAPK signaling pathway)","K04459","EC:3.1.3.16;EC:3.1.3.48","dual specificity phosphatase 8 [Source:HGNC Symbol;Acc:HGNC:3074]",{"v":0.603172528812825,"d":"0.60"},{"v":0.179927126299827,"d":"0.18"},{"v":3.35231569145227,"d":"3.35"},{"v":1.74515801569807,"d":"1.75"},{"v":0.0380771597121841,"d":"0.04"},{"v":0.471984281412782,"d":"0.47"},"up","yes"]
["MSTRG.15474","IDS;LINC00893;AC244197.3;AC244197.2","MSTRG.15474.2;ENST00000428056;ENST00000466323;ENST00000340855;ENST00000370441;ENST00000609314;ENST00000521702;ENST00000437981;ENST00000618757;ENST00000422081;ENST00000431214;ENST00000370438;ENST00000412882;ENST00000464251;ENST00000608342;ENST00000427113;ENST00000441880;ENST00000523759;ENST00000490775;ENST00000608355;ENST00000466019;ENST00000608616","GO:0046872(metal ion binding);GO:0016787(hydrolase activity);GO:0003824(catalytic activity);GO:0008152(metabolic process);GO:0008484(sulfuric ester hydrolase activity);GO:0005764(lysosome);GO:0043202(lysosomal lumen);GO:0006027(glycosaminoglycan catabolic process);GO:0030207(chondroitin sulfate catabolic process);GO:0004423(iduronate-2-sulfatase activity);GO:0004423(iduronate-2-sulfatase activity)","00531(Glycosaminoglycan degradation);04142(Lysosome);04142(Lysosome)","K01136","EC:3.1.6.13","iduronate 2-sulfatase [Source:HGNC Symbol;Acc:HGNC:5389];long intergenic non-protein coding RNA 893 [Source:HGNC Symbol;Acc:HGNC:44265]",{"v":29.3231782824379,"d":"29.32"},{"v":9.34471375662786,"d":"9.34"},{"v":3.13794291041179,"d":"3.14"},{"v":1.64981910513742,"d":"1.65"},{"v":0.0380822588206128,"d":"0.04"},{"v":0.471984281412782,"d":"0.47"},"up","yes"]
["MSTRG.2022","NSMCE4A","ENST00000369023;ENST00000468209;ENST00000472431;ENST00000483541;ENST00000481320;ENST00000369017;ENST00000477289;ENST00000489266;ENST00000459911","GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005694(chromosome);GO:0006281(DNA repair);GO:0005515(protein binding);GO:0006310(DNA recombination);GO:0006974(cellular response to DNA damage stimulus);GO:0016604(nuclear body);GO:0030915(Smc5-Smc6 complex);GO:0000781(chromosome, telomeric region);GO:2001022(positive regulation of response to DNA damage stimulus);GO:2001022(positive regulation of response to DNA damage stimulus)","NA","NA","NA","NSE4 homolog A, SMC5-SMC6 complex component [Source:HGNC Symbol;Acc:HGNC:25935]",{"v":1.73491825211506,"d":"1.73"},{"v":3.79640557529611,"d":"3.80"},{"v":0.456989701891832,"d":"0.46"},{"v":-1.12976643988188,"d":"-1.13"},{"v":0.0381605738737597,"d":"0.04"},{"v":0.472450686989309,"d":"0.47"},"down","yes"]
["MSTRG.12908","HLA-DQB1;HLA-DQB2","MSTRG.12908.7;ENST00000374943;ENST00000443574;ENST00000434651;ENST00000435145;ENST00000487676;ENST00000399079","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0006955(immune response);GO:0002376(immune system process);GO:0002504(antigen processing and presentation of peptide or polysaccharide antigen via MHC class II);GO:0019882(antigen processing and presentation);GO:0042613(MHC class II protein complex);GO:0005794(Golgi apparatus);GO:0005765(lysosomal membrane);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005886(plasma membrane);GO:0005764(lysosome);GO:0005768(endosome);GO:0050852(T cell receptor signaling pathway);GO:0010008(endosome membrane);GO:0019886(antigen processing and presentation of exogenous peptide antigen via MHC class II);GO:0032588(trans-Golgi network membrane);GO:0000139(Golgi membrane);GO:0030666(endocytic vesicle membrane);GO:0060333(interferon-gamma-mediated signaling pathway);GO:0012507(ER to Golgi transport vesicle membrane);GO:0031295(T cell costimulation);GO:0071556(integral component of lumenal side of endoplasmic reticulum membrane);GO:0030669(clathrin-coated endocytic vesicle membrane);GO:0030658(transport vesicle membrane);GO:0032395(MHC class II receptor activity);GO:0042613(MHC class II protein complex)","04514(Cell adhesion molecules (CAMs));04145(Phagosome);04640(Hematopoietic cell lineage);04612(Antigen processing and presentation);04658(Th1 and Th2 cell differentiation);04659(Th17 cell differentiation);04672(Intestinal immune network for IgA production);05310(Asthma);05322(Systemic lupus erythematosus);05323(Rheumatoid arthritis);05320(Autoimmune thyroid disease);05321(Inflammatiory bowel disease (IBD));05330(Allograft rejection);05332(Graft-versus-host disease);05416(Viral myocarditis);04940(Type I diabetes mellitus);05150(Staphylococcus aureus infection);05152(Tuberculosis);05166(HTLV-I infection);05164(Influenza A);05168(Herpes simplex infection);05169(Epstein-Barr virus infection);05145(Toxoplasmosis);05140(Leishmaniasis);05140(Leishmaniasis)","K06752","NA","major histocompatibility complex, class II, DQ beta 1 [Source:HGNC Symbol;Acc:HGNC:4944];major histocompatibility complex, class II, DQ beta 2 [Source:HGNC Symbol;Acc:HGNC:4945]",{"v":0.612016710617427,"d":"0.61"},{"v":1.34523033222735,"d":"1.35"},{"v":0.454953100562405,"d":"0.45"},{"v":-1.13621026402308,"d":"-1.14"},{"v":0.0382230457465532,"d":"0.04"},{"v":0.472720160015679,"d":"0.47"},"down","yes"]
["MSTRG.8638","RPLP0P6","ENST00000394878","NA","NA","NA","NA","ribosomal protein lateral stalk subunit P0 pseudogene 6 [Source:HGNC Symbol;Acc:HGNC:36404]",{"v":51.708057,"d":"51.71"},{"v":111.63974,"d":"111.64"},{"v":0.463168912790374,"d":"0.46"},{"v":-1.11038966985952,"d":"-1.11"},{"v":0.0382915787783663,"d":"0.04"},{"v":0.473063940801243,"d":"0.47"},"down","yes"]
["MSTRG.6779","IKZF3","ENST00000583368;ENST00000346872;ENST00000350532;ENST00000377958;ENST00000377944;ENST00000439016;ENST00000623724;ENST00000377945;ENST00000293068;ENST00000346243;ENST00000348427;ENST00000535189;ENST00000467757;ENST00000351680","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0006366(transcription from RNA polymerase II promoter);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0005886(plasma membrane);GO:0042803(protein homodimerization activity);GO:0005515(protein binding);GO:0042802(identical protein binding);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0042113(B cell activation);GO:0043565(sequence-specific DNA binding);GO:0042981(regulation of apoptotic process);GO:0046982(protein heterodimerization activity);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0007498(mesoderm development);GO:0044212(transcription regulatory region DNA binding);GO:0045577(regulation of B cell differentiation);GO:0030888(regulation of B cell proliferation);GO:0000977(RNA polymerase II regulatory region sequence-specific DNA binding);GO:0001228(transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding);GO:0045619(regulation of lymphocyte differentiation);GO:0045619(regulation of lymphocyte differentiation)","NA","NA","NA","IKAROS family zinc finger 3 [Source:HGNC Symbol;Acc:HGNC:13178]",{"v":17.9121794243605,"d":"17.91"},{"v":5.7114438042566,"d":"5.71"},{"v":3.13619113454482,"d":"3.14"},{"v":1.64901348689478,"d":"1.65"},{"v":0.0383351012952195,"d":"0.04"},{"v":0.473098332987655,"d":"0.47"},"up","yes"]
["MSTRG.6794","WIPF2","ENST00000323571;ENST00000583130;ENST00000578304;ENST00000585043;ENST00000582781;ENST00000584296;ENST00000578623;ENST00000494757","GO:0005737(cytoplasm);GO:0003779(actin binding);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0038096(Fc-gamma receptor signaling pathway involved in phagocytosis);GO:0005829(cytosol);GO:0005829(cytosol)","04144(Endocytosis);04144(Endocytosis)","K19475","NA","WAS/WASL interacting protein family member 2 [Source:HGNC Symbol;Acc:HGNC:30923]",{"v":5.64560549378309,"d":"5.65"},{"v":1.79820348873569,"d":"1.80"},{"v":3.13958099244513,"d":"3.14"},{"v":1.65057203030865,"d":"1.65"},{"v":0.0383800501201943,"d":"0.04"},{"v":0.473115491247728,"d":"0.47"},"up","yes"]
["MSTRG.6319","ZZEF1","MSTRG.6319.1;ENST00000573183;ENST00000570365;ENST00000572699;ENST00000572426;ENST00000571436;ENST00000573606;ENST00000574474;ENST00000575428;ENST00000573536","GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0005509(calcium ion binding);GO:0005509(calcium ion binding)","NA","NA","NA","zinc finger ZZ-type and EF-hand domain containing 1 [Source:HGNC Symbol;Acc:HGNC:29027]",{"v":8.18207954738552,"d":"8.18"},{"v":2.60885502492659,"d":"2.61"},{"v":3.1362722225685,"d":"3.14"},{"v":1.64905078812175,"d":"1.65"},{"v":0.0384179719492472,"d":"0.04"},{"v":0.473115491247728,"d":"0.47"},"up","yes"]
["MSTRG.5628","C16orf72;AC087190.4","ENST00000574285;ENST00000327827;ENST00000574616","GO:0005515(protein binding);GO:0005515(protein binding)","NA","NA","NA","chromosome 16 open reading frame 72 [Source:HGNC Symbol;Acc:HGNC:30103]",{"v":13.7244394274016,"d":"13.72"},{"v":4.3873587856378,"d":"4.39"},{"v":3.1281780446881,"d":"3.13"},{"v":1.64532262801564,"d":"1.65"},{"v":0.0387228346122385,"d":"0.04"},{"v":0.476364701643989,"d":"0.48"},"up","yes"]
["MSTRG.10426","IL2RB","ENST00000216223;ENST00000445595;ENST00000461607;ENST00000440958;ENST00000483573","GO:0005622(intracellular);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0043547(positive regulation of GTPase activity);GO:0005515(protein binding);GO:0004896(cytokine receptor activity);GO:0005886(plasma membrane);GO:0000165(MAPK cascade);GO:0016032(viral process);GO:0005887(integral component of plasma membrane);GO:0038110(interleukin-2-mediated signaling pathway);GO:0007165(signal transduction);GO:0006461(protein complex assembly);GO:0005088(Ras guanyl-nucleotide exchange factor activity);GO:0009897(external side of plasma membrane);GO:0043066(negative regulation of apoptotic process);GO:0004911(interleukin-2 receptor activity);GO:0019976(interleukin-2 binding);GO:0019221(cytokine-mediated signaling pathway);GO:0019221(cytokine-mediated signaling pathway)","04630(Jak-STAT signaling pathway);04151(PI3K-Akt signaling pathway);04060(Cytokine-cytokine receptor interaction);04144(Endocytosis);04658(Th1 and Th2 cell differentiation);04659(Th17 cell differentiation);05200(Pathways in cancer);05202(Transcriptional misregulation in cancers);05166(HTLV-I infection);05162(Measles);05162(Measles)","K05069","NA","interleukin 2 receptor subunit beta [Source:HGNC Symbol;Acc:HGNC:6009]",{"v":31.2160240519149,"d":"31.22"},{"v":9.9879733206383,"d":"9.99"},{"v":3.12536117686786,"d":"3.13"},{"v":1.64402292192411,"d":"1.64"},{"v":0.0389264510573269,"d":"0.04"},{"v":0.477949525858052,"d":"0.48"},"up","yes"]
["MSTRG.7977","RPL18A","ENST00000597648;ENST00000599870;ENST00000599898;ENST00000222247;ENST00000602216;MSTRG.7977.1;ENST00000600147;ENST00000600238","GO:0003723(RNA binding);GO:0016020(membrane);GO:0006412(translation);GO:0030529(intracellular ribonucleoprotein complex);GO:0003735(structural constituent of ribosome);GO:0005840(ribosome);GO:0005829(cytosol);GO:0005515(protein binding);GO:0006413(translational initiation);GO:0006364(rRNA processing);GO:0000184(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay);GO:0019083(viral transcription);GO:0006614(SRP-dependent cotranslational protein targeting to membrane);GO:0022625(cytosolic large ribosomal subunit);GO:0097327(response to antineoplastic agent);GO:0097327(response to antineoplastic agent)","03010(Ribosome);03010(Ribosome)","K02882","NA","ribosomal protein L18a [Source:HGNC Symbol;Acc:HGNC:10311]",{"v":94.9586952117141,"d":"94.96"},{"v":204.160860763299,"d":"204.16"},{"v":0.465117039851276,"d":"0.47"},{"v":-1.10433430002889,"d":"-1.10"},{"v":0.0389339749816341,"d":"0.04"},{"v":0.477949525858052,"d":"0.48"},"down","yes"]
["MSTRG.6378","ALOX12-AS1;MIR497HG","ENST00000399540;ENST00000575727;ENST00000575889;ENST00000572385;ENST00000573939;ENST00000399541;ENST00000570562;ENST00000571010;ENST00000574377;ENST00000572453","NA","NA","NA","NA","ALOX12 antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:51342];mir-497-195 cluster host gene [Source:HGNC Symbol;Acc:HGNC:39523]",{"v":0.253181296642584,"d":"0.25"},{"v":0.571143913443831,"d":"0.57"},{"v":0.443288093741514,"d":"0.44"},{"v":-1.17368348115646,"d":"-1.17"},{"v":0.0391917416869552,"d":"0.04"},{"v":0.480605803812683,"d":"0.48"},"down","yes"]
["MSTRG.8702","SPTBN1","MSTRG.8702.5;ENST00000467371;ENST00000496323;ENST00000333896;ENST00000615901","GO:0003723(RNA binding);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0003779(actin binding);GO:0005886(plasma membrane);GO:0051693(actin filament capping);GO:0043547(positive regulation of GTPase activity);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0005200(structural constituent of cytoskeleton);GO:0007010(cytoskeleton organization);GO:0005543(phospholipid binding);GO:0008091(spectrin);GO:0005516(calmodulin binding);GO:0005829(cytosol);GO:0045296(cadherin binding);GO:0070062(extracellular exosome);GO:0000165(MAPK cascade);GO:0031430(M band);GO:0032403(protein complex binding);GO:0007182(common-partner SMAD protein phosphorylation);GO:0007184(SMAD protein import into nucleus);GO:0072661(protein targeting to plasma membrane);GO:0005634(nucleus);GO:0014069(postsynaptic density);GO:0030673(axolemma);GO:0030863(cortical cytoskeleton);GO:0032437(cuticular plate);GO:0043234(protein complex);GO:0007411(axon guidance);GO:0006888(ER to Golgi vesicle-mediated transport);GO:0005088(Ras guanyl-nucleotide exchange factor activity);GO:1903076(regulation of protein localization to plasma membrane);GO:0030506(ankyrin binding);GO:0051020(GTPase binding);GO:0005730(nucleolus);GO:0014731(spectrin-associated cytoskeleton);GO:0007009(plasma membrane organization);GO:0000281(mitotic cytokinesis);GO:0043001(Golgi to plasma membrane protein transport);GO:0071709(membrane assembly);GO:1900042(positive regulation of interleukin-2 secretion);GO:1903078(positive regulation of protein localization to plasma membrane);GO:1903078(positive regulation of protein localization to plasma membrane)","NA","NA","NA","spectrin beta, non-erythrocytic 1 [Source:HGNC Symbol;Acc:HGNC:11275]",{"v":6.88230251755142,"d":"6.88"},{"v":2.20617941132766,"d":"2.21"},{"v":3.11955704155978,"d":"3.12"},{"v":1.64134118956387,"d":"1.64"},{"v":0.0393148972870576,"d":"0.04"},{"v":0.480808354723898,"d":"0.48"},"up","yes"]
["MSTRG.7210","MIF4GD","ENST00000325102;ENST00000618645;ENST00000580717;ENST00000581777;MSTRG.7210.2;ENST00000579194;ENST00000579119;ENST00000245551;ENST00000579297;ENST00000577240;ENST00000577542;ENST00000580099","GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005730(nucleolus);GO:0005829(cytosol);GO:0005515(protein binding);GO:0006417(regulation of translation);GO:0008022(protein C-terminus binding);GO:0008022(protein C-terminus binding)","NA","NA","NA","MIF4G domain containing [Source:HGNC Symbol;Acc:HGNC:24030]",{"v":3.01693960398136,"d":"3.02"},{"v":6.53810882719187,"d":"6.54"},{"v":0.461439184284294,"d":"0.46"},{"v":-1.11578757553849,"d":"-1.12"},{"v":0.0393315641941247,"d":"0.04"},{"v":0.480808354723898,"d":"0.48"},"down","yes"]
["ENSG00000100335","MIEF1","ENST00000325301;ENST00000434364;ENST00000494219;ENST00000402881;ENST00000433117;ENST00000428069;ENST00000404569;ENST00000478342","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0071456(cellular response to hypoxia);GO:0090141(positive regulation of mitochondrial fission);GO:0005739(mitochondrion);GO:0000166(nucleotide binding);GO:0005515(protein binding);GO:0005741(mitochondrial outer membrane);GO:0042802(identical protein binding);GO:0090314(positive regulation of protein targeting to membrane);GO:0000266(mitochondrial fission);GO:0043531(ADP binding);GO:0019003(GDP binding);GO:0019003(GDP binding)","NA","NA","NA","mitochondrial elongation factor 1 [Source:HGNC Symbol;Acc:HGNC:25979]",{"v":2.782811825546,"d":"2.78"},{"v":0.879951113434811,"d":"0.88"},{"v":3.16246184936745,"d":"3.16"},{"v":1.66104807583529,"d":"1.66"},{"v":0.0393403445514648,"d":"0.04"},{"v":0.480808354723898,"d":"0.48"},"up","yes"]
["ENSG00000254206","NPIPB11","ENST00000524087;ENST00000614927","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005654(nucleoplasm);GO:0005654(nucleoplasm)","NA","NA","NA","nuclear pore complex interacting protein family member B11 [Source:HGNC Symbol;Acc:HGNC:37453]",{"v":0.80052104638472,"d":"0.80"},{"v":0.24422859572533,"d":"0.24"},{"v":3.27775313946046,"d":"3.28"},{"v":1.71270720346508,"d":"1.71"},{"v":0.0393738694000196,"d":"0.04"},{"v":0.480808354723898,"d":"0.48"},"up","yes"]
["MSTRG.8984","TMEM131","ENST00000186436;ENST00000485245;ENST00000409721;ENST00000489507;ENST00000469447;ENST00000480724;ENST00000465767","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0003674(molecular_function);GO:0008150(biological_process);GO:0005575(cellular_component);GO:0005575(cellular_component)","NA","NA","NA","transmembrane protein 131 [Source:HGNC Symbol;Acc:HGNC:30366]",{"v":4.23093337504813,"d":"4.23"},{"v":1.35504506815556,"d":"1.36"},{"v":3.12235620384725,"d":"3.12"},{"v":1.64263513187377,"d":"1.64"},{"v":0.0394692344006306,"d":"0.04"},{"v":0.481466616695928,"d":"0.48"},"up","yes"]
["MSTRG.4417","ATG14","ENST00000247178;ENST00000558189","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005515(protein binding);GO:0006914(autophagy);GO:0031410(cytoplasmic vesicle);GO:0034045(pre-autophagosomal structure membrane);GO:0005829(cytosol);GO:0000045(autophagosome assembly);GO:0001934(positive regulation of protein phosphorylation);GO:0000421(autophagosome membrane);GO:0016236(macroautophagy);GO:0005930(axoneme);GO:0005776(autophagosome);GO:0008333(endosome to lysosome transport);GO:0010508(positive regulation of autophagy);GO:0001933(negative regulation of protein phosphorylation);GO:0042149(cellular response to glucose starvation);GO:0051020(GTPase binding);GO:0097629(extrinsic component of omegasome membrane);GO:0097632(extrinsic component of pre-autophagosomal structure membrane);GO:0016240(autophagosome docking);GO:0043552(positive regulation of phosphatidylinositol 3-kinase activity);GO:0009267(cellular response to starvation);GO:0061635(regulation of protein complex stability);GO:0000423(macromitophagy);GO:0098780(response to mitochondrial depolarisation);GO:0035032(phosphatidylinositol 3-kinase complex, class III);GO:0001932(regulation of protein phosphorylation);GO:0010608(posttranscriptional regulation of gene expression);GO:0090207(regulation of triglyceride metabolic process);GO:0044233(ER-mitochondrion membrane contact site);GO:0045335(phagocytic vesicle);GO:0045335(phagocytic vesicle)","04140(Autophagy - animal);05167(Kaposi's sarcoma-associated herpesvirus infection);05167(Kaposi's sarcoma-associated herpesvirus infection)","K17889","NA","autophagy related 14 [Source:HGNC Symbol;Acc:HGNC:19962]",{"v":1.18000368863816,"d":"1.18"},{"v":2.55412361243072,"d":"2.55"},{"v":0.461999443916956,"d":"0.46"},{"v":-1.11403697973679,"d":"-1.11"},{"v":0.039553638950981,"d":"0.04"},{"v":0.481989936136141,"d":"0.48"},"down","yes"]
["MSTRG.13097","TRAM2","ENST00000182527","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0015031(protein transport);GO:0045048(protein insertion into ER membrane);GO:0005515(protein binding);GO:0032964(collagen biosynthetic process)","NA","NA","NA","translocation associated membrane protein 2 [Source:HGNC Symbol;Acc:HGNC:16855]",{"v":3.677368,"d":"3.68"},{"v":1.175684,"d":"1.18"},{"v":3.12785408324005,"d":"3.13"},{"v":1.64517321139968,"d":"1.65"},{"v":0.0397042003821265,"d":"0.04"},{"v":0.482751222060519,"d":"0.48"},"up","yes"]
["ENSG00000198420","TCAF1","ENST00000479870;ENST00000478172;ENST00000392900;ENST00000355951","GO:0006810(transport);GO:0016020(membrane);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0044325(ion channel binding);GO:0090314(positive regulation of protein targeting to membrane);GO:0030336(negative regulation of cell migration);GO:1901529(positive regulation of anion channel activity);GO:1901529(positive regulation of anion channel activity)","NA","NA","NA","TRPM8 channel associated factor 1 [Source:HGNC Symbol;Acc:HGNC:22201]",{"v":1.65989961711569,"d":"1.66"},{"v":0.523045495721078,"d":"0.52"},{"v":3.17352817430791,"d":"3.17"},{"v":1.66608765079901,"d":"1.67"},{"v":0.0397080038776138,"d":"0.04"},{"v":0.482751222060519,"d":"0.48"},"up","yes"]
["MSTRG.12994","KCTD20","ENST00000373731;ENST00000443316;ENST00000474988;ENST00000536244;ENST00000449081;ENST00000481911;ENST00000460983;ENST00000483557;ENST00000498267;ENST00000265344","GO:0005737(cytoplasm);GO:0042327(positive regulation of phosphorylation);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016021(integral component of membrane)","NA","NA","NA","potassium channel tetramerization domain containing 20 [Source:HGNC Symbol;Acc:HGNC:21052]",{"v":4.55890625853502,"d":"4.56"},{"v":9.78748847812149,"d":"9.79"},{"v":0.4657891826617,"d":"0.47"},{"v":-1.10225095963557,"d":"-1.10"},{"v":0.039740822206997,"d":"0.04"},{"v":0.482751222060519,"d":"0.48"},"down","yes"]
["MSTRG.7861","RNASEH2A","ENST00000221486;ENST00000593017;ENST00000639767;ENST00000590279;ENST00000590121","GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0016787(hydrolase activity);GO:0090305(nucleic acid phosphodiester bond hydrolysis);GO:0004519(endonuclease activity);GO:0090502(RNA phosphodiester bond hydrolysis, endonucleolytic);GO:0004518(nuclease activity);GO:0004523(RNA-DNA hybrid ribonuclease activity);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0016070(RNA metabolic process);GO:0090501(RNA phosphodiester bond hydrolysis);GO:0006260(DNA replication);GO:0004540(ribonuclease activity);GO:0006401(RNA catabolic process);GO:0043137(DNA replication, removal of RNA primer);GO:0006298(mismatch repair);GO:0032299(ribonuclease H2 complex);GO:0032299(ribonuclease H2 complex)","03030(DNA replication);03030(DNA replication)","K10743","EC:3.1.26.4","ribonuclease H2 subunit A [Source:HGNC Symbol;Acc:HGNC:18518]",{"v":0.982944410074938,"d":"0.98"},{"v":2.16462785595337,"d":"2.16"},{"v":0.454093948468578,"d":"0.45"},{"v":-1.1389372842263,"d":"-1.14"},{"v":0.0397922201371209,"d":"0.04"},{"v":0.482870483231332,"d":"0.48"},"down","yes"]
["MSTRG.12509","ADAM19","ENST00000257527;MSTRG.12509.4;ENST00000519752;ENST00000517951;ENST00000517905;ENST00000517374","GO:0016021(integral component of membrane);GO:0017124(SH3 domain binding);GO:0006508(proteolysis);GO:0005794(Golgi apparatus);GO:0004222(metalloendopeptidase activity);GO:0008237(metallopeptidase activity);GO:0006509(membrane protein ectodomain proteolysis);GO:0016020(membrane);GO:0046872(metal ion binding);GO:0016787(hydrolase activity);GO:0008233(peptidase activity);GO:0005886(plasma membrane);GO:0030198(extracellular matrix organization);GO:0007507(heart development);GO:0007507(heart development)","NA","NA","NA","ADAM metallopeptidase domain 19 [Source:HGNC Symbol;Acc:HGNC:197]",{"v":13.1617321678095,"d":"13.16"},{"v":4.23140886039591,"d":"4.23"},{"v":3.11048461683706,"d":"3.11"},{"v":1.63713937130129,"d":"1.64"},{"v":0.0400777994844643,"d":"0.04"},{"v":0.485828272873782,"d":"0.49"},"up","yes"]
["ENSG00000197892","KIF13B","ENST00000524189;ENST00000523968;ENST00000523130;ENST00000522355;ENST00000521515;ENST00000522846","GO:0005737(cytoplasm);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0003777(microtubule motor activity);GO:0005856(cytoskeleton);GO:0042995(cell projection);GO:0005515(protein binding);GO:0007165(signal transduction);GO:0008017(microtubule binding);GO:0005874(microtubule);GO:0007018(microtubule-based movement);GO:0072383(plus-end-directed vesicle transport along microtubule);GO:0030424(axon);GO:0019901(protein kinase binding);GO:0030705(cytoskeleton-dependent intracellular transport);GO:0016887(ATPase activity);GO:0005871(kinesin complex);GO:0006605(protein targeting);GO:0042110(T cell activation);GO:0071889(14-3-3 protein binding);GO:0050770(regulation of axonogenesis);GO:0005829(cytosol);GO:0005902(microvillus);GO:0033270(paranode region of axon);GO:0003774(motor activity);GO:0003774(motor activity)","NA","NA","NA","kinesin family member 13B [Source:HGNC Symbol;Acc:HGNC:14405]",{"v":2.93173910430166,"d":"2.93"},{"v":0.939267335943125,"d":"0.94"},{"v":3.12130422523198,"d":"3.12"},{"v":1.64214897976381,"d":"1.64"},{"v":0.0401942586229861,"d":"0.04"},{"v":0.486731934711926,"d":"0.49"},"up","yes"]
["ENSG00000148943","LIN7C","ENST00000278193","GO:0006810(transport);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0015031(protein transport);GO:0005886(plasma membrane);GO:0030054(cell junction);GO:0045202(synapse);GO:0045211(postsynaptic membrane);GO:0098793(presynapse);GO:0005923(bicellular tight junction);GO:0006887(exocytosis);GO:0070062(extracellular exosome);GO:0045199(maintenance of epithelial cell apical/basal polarity);GO:0016323(basolateral plasma membrane);GO:0019904(protein domain specific binding);GO:0014069(postsynaptic density);GO:0043005(neuron projection);GO:0005911(cell-cell junction);GO:0008092(cytoskeletal protein binding);GO:0007269(neurotransmitter secretion);GO:1903361(protein localization to basolateral plasma membrane);GO:0002011(morphogenesis of an epithelial sheet);GO:0030165(PDZ domain binding);GO:0097016(L27 domain binding);GO:0097025(MPP7-DLG1-LIN7 complex)","NA","NA","NA","lin-7 homolog C, crumbs cell polarity complex component [Source:HGNC Symbol;Acc:HGNC:17789]",{"v":1.161653,"d":"1.16"},{"v":2.503242,"d":"2.50"},{"v":0.464059407760017,"d":"0.46"},{"v":-1.10761858739117,"d":"-1.11"},{"v":0.040246612781491,"d":"0.04"},{"v":0.486858243991099,"d":"0.49"},"down","yes"]
["MSTRG.367","TMEM234","ENST00000309777;ENST00000461402;ENST00000491434;ENST00000483001;ENST00000373593;ENST00000487174;ENST00000344461;ENST00000489170;ENST00000485689;ENST00000466796","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005515(protein binding);GO:0005515(protein binding)","NA","NA","NA","transmembrane protein 234 [Source:HGNC Symbol;Acc:HGNC:28837]",{"v":0.781780430971717,"d":"0.78"},{"v":1.71775877233268,"d":"1.72"},{"v":0.455116541136958,"d":"0.46"},{"v":-1.13569207311083,"d":"-1.14"},{"v":0.0403916411357079,"d":"0.04"},{"v":0.488104191996853,"d":"0.49"},"down","yes"]
["ENSG00000145990","GFOD1","ENST00000379287;ENST00000603223;ENST00000605067;ENST00000379284","GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0008152(metabolic process);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0005576(extracellular region)","NA","NA","NA","glucose-fructose oxidoreductase domain containing 1 [Source:HGNC Symbol;Acc:HGNC:21096]",{"v":1.38207387956204,"d":"1.38"},{"v":0.440954591240876,"d":"0.44"},{"v":3.1342771047531,"d":"3.13"},{"v":1.64813273564336,"d":"1.65"},{"v":0.0405065067313554,"d":"0.04"},{"v":0.488983433130177,"d":"0.49"},"up","yes"]
["MSTRG.2071","LINC01001","ENST00000526704;ENST00000607448;ENST00000527683","NA","NA","NA","NA","long intergenic non-protein coding RNA 1001 [Source:HGNC Symbol;Acc:HGNC:38540]",{"v":5.7465750402825,"d":"5.75"},{"v":1.84063604525242,"d":"1.84"},{"v":3.12205938545251,"d":"3.12"},{"v":1.64249797943081,"d":"1.64"},{"v":0.0406377350924018,"d":"0.04"},{"v":0.490058169914914,"d":"0.49"},"up","yes"]
["MSTRG.898","NBPF19","ENST00000611931;ENST00000621744;ENST00000369227;ENST00000578189;ENST00000612881;ENST00000426482","GO:0005737(cytoplasm);GO:0005737(cytoplasm)","NA","NA","NA","NBPF member 19 [Source:HGNC Symbol;Acc:HGNC:31999]",{"v":4.12929574069737,"d":"4.13"},{"v":1.33137876837903,"d":"1.33"},{"v":3.10151839489287,"d":"3.10"},{"v":1.63297468146037,"d":"1.63"},{"v":0.0407201567010002,"d":"0.04"},{"v":0.490542717602402,"d":"0.49"},"up","yes"]
["MSTRG.10620","SUMF1","ENST00000272902;ENST00000458465;ENST00000383843;ENST00000448413;ENST00000470751;ENST00000405420","GO:0046872(metal ion binding);GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0005783(endoplasmic reticulum);GO:0005788(endoplasmic reticulum lumen);GO:0006687(glycosphingolipid metabolic process);GO:0043687(post-translational protein modification);GO:0042803(protein homodimerization activity);GO:0042803(protein homodimerization activity)","04142(Lysosome);04142(Lysosome)","K13444","EC:1.8.3.7","sulfatase modifying factor 1 [Source:HGNC Symbol;Acc:HGNC:20376]",{"v":1.36212285140967,"d":"1.36"},{"v":2.92002231962025,"d":"2.92"},{"v":0.466476862953162,"d":"0.47"},{"v":-1.10012256907406,"d":"-1.10"},{"v":0.0409748654348856,"d":"0.04"},{"v":0.492855757001042,"d":"0.49"},"down","yes"]
["ENSG00000156650","KAT6B","ENST00000287239;ENST00000372711;ENST00000372714;ENST00000604130;ENST00000372725;ENST00000490365;ENST00000372724","GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0016740(transferase activity);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0016569(covalent chromatin modification);GO:0003677(DNA binding);GO:0016746(transferase activity, transferring acyl groups);GO:0006334(nucleosome assembly);GO:0000786(nucleosome);GO:0016747(transferase activity, transferring acyl groups other than amino-acyl groups);GO:0004402(histone acetyltransferase activity);GO:0045893(positive regulation of transcription, DNA-templated);GO:0005515(protein binding);GO:0005654(nucleoplasm);GO:0008134(transcription factor binding);GO:0045892(negative regulation of transcription, DNA-templated);GO:0043966(histone H3 acetylation);GO:0070776(MOZ/MORF histone acetyltransferase complex);GO:0016407(acetyltransferase activity);GO:0016573(histone acetylation);GO:0032403(protein complex binding);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:1990830(cellular response to leukemia inhibitory factor);GO:1990830(cellular response to leukemia inhibitory factor)","NA","NA","NA","lysine acetyltransferase 6B [Source:HGNC Symbol;Acc:HGNC:17582]",{"v":2.631304485,"d":"2.63"},{"v":0.847333120149254,"d":"0.85"},{"v":3.10539553149593,"d":"3.11"},{"v":1.6347770349468,"d":"1.63"},{"v":0.0409970430778444,"d":"0.04"},{"v":0.492855757001042,"d":"0.49"},"up","yes"]
["MSTRG.2371","PSMC3","ENST00000298852;ENST00000619920;ENST00000602866;ENST00000530651;ENST00000530887;ENST00000531653;ENST00000527906;ENST00000526993;ENST00000528362;ENST00000531051;ENST00000524447;ENST00000529500","GO:0005737(cytoplasm);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0016787(hydrolase activity);GO:0030163(protein catabolic process);GO:0036402(proteasome-activating ATPase activity);GO:1901800(positive regulation of proteasomal protein catabolic process);GO:0005634(nucleus);GO:0016020(membrane);GO:0005515(protein binding);GO:0000502(proteasome complex);GO:0038095(Fc-epsilon receptor signaling pathway);GO:0005576(extracellular region);GO:0042802(identical protein binding);GO:0000932(P-body);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0000165(MAPK cascade);GO:0000209(protein polyubiquitination);GO:0002223(stimulatory C-type lectin receptor signaling pathway);GO:0002479(antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent);GO:0006521(regulation of cellular amino acid metabolic process);GO:0010972(negative regulation of G2/M transition of mitotic cell cycle);GO:0016579(protein deubiquitination);GO:0031145(anaphase-promoting complex-dependent catabolic process);GO:0031146(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process);GO:0033209(tumor necrosis factor-mediated signaling pathway);GO:0038061(NIK/NF-kappaB signaling);GO:0043161(proteasome-mediated ubiquitin-dependent protein catabolic process);GO:0043488(regulation of mRNA stability);GO:0043687(post-translational protein modification);GO:0050852(T cell receptor signaling pathway);GO:0051437(positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition);GO:0055085(transmembrane transport);GO:0060071(Wnt signaling pathway, planar cell polarity pathway);GO:0061418(regulation of transcription from RNA polymerase II promoter in response to hypoxia);GO:0090090(negative regulation of canonical Wnt signaling pathway);GO:0090263(positive regulation of canonical Wnt signaling pathway);GO:1902036(regulation of hematopoietic stem cell differentiation);GO:0016887(ATPase activity);GO:0016032(viral process);GO:0043312(neutrophil degranulation);GO:0051436(negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle);GO:0022624(proteasome accessory complex);GO:0034774(secretory granule lumen);GO:1904813(ficolin-1-rich granule lumen);GO:0031595(nuclear proteasome complex);GO:0030433(ubiquitin-dependent ERAD pathway);GO:0017025(TBP-class protein binding);GO:0043921(modulation by host of viral transcription);GO:0045899(positive regulation of RNA polymerase II transcriptional preinitiation complex assembly);GO:0008540(proteasome regulatory particle, base subcomplex);GO:0031597(cytosolic proteasome complex);GO:0001824(blastocyst development);GO:0001824(blastocyst development)","03050(Proteasome);05169(Epstein-Barr virus infection);05169(Epstein-Barr virus infection)","K03065","NA","proteasome 26S subunit, ATPase 3 [Source:HGNC Symbol;Acc:HGNC:9549]",{"v":7.97848569332162,"d":"7.98"},{"v":17.0409991278559,"d":"17.04"},{"v":0.468193539208606,"d":"0.47"},{"v":-1.09482306863055,"d":"-1.09"},{"v":0.0411650356591719,"d":"0.04"},{"v":0.493999491270694,"d":"0.49"},"down","yes"]
["MSTRG.14017","NDUFB2;ADCK2","ENST00000247866;ENST00000072869;ENST00000482954;ENST00000476491;ENST00000464566;ENST00000472695;ENST00000479181;ENST00000460088;ENST00000476279;ENST00000465506;ENST00000461457;ENST00000475276;ENST00000471136;ENST00000476470;ENST00000476181;ENST00000462847;ENST00000464564","GO:0005743(mitochondrial inner membrane);GO:0005747(mitochondrial respiratory chain complex I);GO:0016020(membrane);GO:0055114(oxidation-reduction process);GO:0005739(mitochondrion);GO:0070469(respiratory chain);GO:0032981(mitochondrial respiratory chain complex I assembly);GO:0008137(NADH dehydrogenase (ubiquinone) activity);GO:0006120(mitochondrial electron transport, NADH to ubiquinone);GO:0016021(integral component of membrane);GO:0000166(nucleotide binding);GO:0004674(protein serine/threonine kinase activity);GO:0005524(ATP binding);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0006468(protein phosphorylation);GO:0004672(protein kinase activity);GO:0006120(mitochondrial electron transport, NADH to ubiquinone)","00190(Oxidative phosphorylation);04723(Retrograde endocannabinoid signaling);05010(Alzheimer's disease);05012(Parkinson's disease);05016(Huntington's disease);04932(Non-alcoholic fatty liver disease (NAFLD));04932(Non-alcoholic fatty liver disease (NAFLD))","K03958","NA","NADH:ubiquinone oxidoreductase subunit B2 [Source:HGNC Symbol;Acc:HGNC:7697];aarF domain containing kinase 2 [Source:HGNC Symbol;Acc:HGNC:19039]",{"v":1.82065013500548,"d":"1.82"},{"v":3.88913113294956,"d":"3.89"},{"v":0.468138016633211,"d":"0.47"},{"v":-1.09499416645113,"d":"-1.09"},{"v":0.0411772588952064,"d":"0.04"},{"v":0.493999491270694,"d":"0.49"},"down","yes"]
["MSTRG.1766","C10orf105","ENST00000441508","GO:0016020(membrane);GO:0016021(integral component of membrane)","NA","NA","NA","chromosome 10 open reading frame 105 [Source:HGNC Symbol;Acc:HGNC:20304]",{"v":0.924287729981755,"d":"0.92"},{"v":0.287939537806609,"d":"0.29"},{"v":3.21000629862281,"d":"3.21"},{"v":1.6825761281834,"d":"1.68"},{"v":0.0412388294954274,"d":"0.04"},{"v":0.494227581971515,"d":"0.49"},"up","yes"]
["ENSG00000187626","ZKSCAN4","ENST00000377294","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0005622(intracellular);GO:0005515(protein binding)","NA","NA","NA","zinc finger with KRAB and SCAN domains 4 [Source:HGNC Symbol;Acc:HGNC:13854]",{"v":0.584188,"d":"0.58"},{"v":1.303146,"d":"1.30"},{"v":0.448290521553226,"d":"0.45"},{"v":-1.1574940988508,"d":"-1.16"},{"v":0.0412882948396701,"d":"0.04"},{"v":0.494298941420653,"d":"0.49"},"down","yes"]
["ENSG00000008256","CYTH3","ENST00000350796;ENST00000461891;ENST00000495176;ENST00000478541;ENST00000465320;ENST00000466543;ENST00000482460;ENST00000396741","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0005886(plasma membrane);GO:0043547(positive regulation of GTPase activity);GO:0005515(protein binding);GO:0005086(ARF guanyl-nucleotide exchange factor activity);GO:0032012(regulation of ARF protein signal transduction);GO:0005085(guanyl-nucleotide exchange factor activity);GO:0008289(lipid binding);GO:0031234(extrinsic component of cytoplasmic side of plasma membrane);GO:0005547(phosphatidylinositol-3,4,5-trisphosphate binding);GO:0000139(Golgi membrane);GO:0045785(positive regulation of cell adhesion);GO:0048193(Golgi vesicle transport);GO:0090162(establishment of epithelial cell polarity);GO:0001726(ruffle);GO:0001726(ruffle)","04072(Phospholipase D signaling pathway);04144(Endocytosis);04144(Endocytosis)","K18441","NA","cytohesin 3 [Source:HGNC Symbol;Acc:HGNC:9504]",{"v":0.783102508953168,"d":"0.78"},{"v":1.67841368044077,"d":"1.68"},{"v":0.466573001685447,"d":"0.47"},{"v":-1.09982526690822,"d":"-1.10"},{"v":0.0413299123499056,"d":"0.04"},{"v":0.494298941420653,"d":"0.49"},"down","yes"]
["MSTRG.3811","RHOF;LINC01089","ENST00000267205;ENST00000541694;ENST00000542933;ENST00000536662;ENST00000543334;ENST00000546227;ENST00000535614;ENST00000535643;ENST00000429892;ENST00000545885;ENST00000537265;ENST00000543167;ENST00000428029;ENST00000541657;ENST00000545544;ENST00000535560;ENST00000537157;ENST00000537171","GO:0005525(GTP binding);GO:0007264(small GTPase mediated signal transduction);GO:0000166(nucleotide binding);GO:0003924(GTPase activity);GO:0005622(intracellular);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005886(plasma membrane);GO:0005856(cytoskeleton);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0051056(regulation of small GTPase mediated signal transduction);GO:0043312(neutrophil degranulation);GO:0030667(secretory granule membrane);GO:0007015(actin filament organization);GO:0007015(actin filament organization)","NA","NA","NA","ras homolog family member F, filopodia associated [Source:HGNC Symbol;Acc:HGNC:15703];long intergenic non-protein coding RNA 1089 [Source:HGNC Symbol;Acc:HGNC:27886]",{"v":5.36028787472348,"d":"5.36"},{"v":1.727469599022,"d":"1.73"},{"v":3.1029708874519,"d":"3.10"},{"v":1.6336501613443,"d":"1.63"},{"v":0.0414793407789606,"d":"0.04"},{"v":0.494334452856337,"d":"0.49"},"up","yes"]
["ENSG00000177200","CHD9","ENST00000398510;ENST00000564255;ENST00000564582;ENST00000565442;ENST00000569225;ENST00000565119;ENST00000562806;ENST00000562791;ENST00000564845;ENST00000447540;ENST00000561869;ENST00000564641;ENST00000565803;ENST00000219084;ENST00000566029;ENST00000564600","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0016787(hydrolase activity);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0016569(covalent chromatin modification);GO:0004386(helicase activity);GO:0003677(DNA binding);GO:0016817(hydrolase activity, acting on acid anhydrides);GO:0005654(nucleoplasm);GO:0019216(regulation of lipid metabolic process);GO:0019216(regulation of lipid metabolic process)","NA","NA","NA","chromodomain helicase DNA binding protein 9 [Source:HGNC Symbol;Acc:HGNC:25701]",{"v":2.06110558108108,"d":"2.06"},{"v":0.661380381044722,"d":"0.66"},{"v":3.11636939974745,"d":"3.12"},{"v":1.63986625380938,"d":"1.64"},{"v":0.0414899237052266,"d":"0.04"},{"v":0.494334452856337,"d":"0.49"},"up","yes"]
["ENSG00000104691","UBXN8","ENST00000265616;ENST00000620706;ENST00000620074;ENST00000341403;ENST00000380154;ENST00000613013","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005783(endoplasmic reticulum);GO:0005730(nucleolus);GO:0030433(ubiquitin-dependent ERAD pathway);GO:0003676(nucleic acid binding);GO:0090502(RNA phosphodiester bond hydrolysis, endonucleolytic);GO:0004523(RNA-DNA hybrid ribonuclease activity);GO:0005789(endoplasmic reticulum membrane);GO:0005515(protein binding);GO:0007338(single fertilization);GO:0030176(integral component of endoplasmic reticulum membrane);GO:0030176(integral component of endoplasmic reticulum membrane)","NA","NA","NA","UBX domain protein 8 [Source:HGNC Symbol;Acc:HGNC:30307]",{"v":0.563201021448555,"d":"0.56"},{"v":1.24451921168791,"d":"1.24"},{"v":0.452545060099715,"d":"0.45"},{"v":-1.1438666457946,"d":"-1.14"},{"v":0.041539053073952,"d":"0.04"},{"v":0.494334452856337,"d":"0.49"},"down","yes"]
["MSTRG.14284","LEPROTL1;DCTN6","ENST00000321250;ENST00000523116;ENST00000221114;ENST00000518192;ENST00000520829;ENST00000520682;ENST00000522540;ENST00000519466;ENST00000519830;ENST00000522141;ENST00000518001","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005515(protein binding);GO:0005768(endosome);GO:0032511(late endosome to vacuole transport via multivesicular body sorting pathway);GO:2000009(negative regulation of protein localization to cell surface);GO:0005737(cytoplasm);GO:0005694(chromosome);GO:0005856(cytoskeleton);GO:0005813(centrosome);GO:0000775(chromosome, centromeric region);GO:0000776(kinetochore);GO:0000777(condensed chromosome kinetochore);GO:0005869(dynactin complex);GO:0005829(cytosol);GO:0019886(antigen processing and presentation of exogenous peptide antigen via MHC class II);GO:0006888(ER to Golgi vesicle-mediated transport);GO:2000009(negative regulation of protein localization to cell surface)","04962(Vasopressin-regulated water reabsorption);04962(Vasopressin-regulated water reabsorption)","K10428","NA","leptin receptor overlapping transcript like 1 [Source:HGNC Symbol;Acc:HGNC:6555];dynactin subunit 6 [Source:HGNC Symbol;Acc:HGNC:16964]",{"v":10.1807918168088,"d":"10.18"},{"v":3.29113319619634,"d":"3.29"},{"v":3.09340011779986,"d":"3.09"},{"v":1.6291934518015,"d":"1.63"},{"v":0.0415827235248806,"d":"0.04"},{"v":0.494334452856337,"d":"0.49"},"up","yes"]
["MSTRG.14407","LY96","ENST00000284818;ENST00000518893;MSTRG.14407.2","GO:0005515(protein binding);GO:0005576(extracellular region);GO:0005615(extracellular space);GO:0002376(immune system process);GO:0045087(innate immune response);GO:0006954(inflammatory response);GO:0005886(plasma membrane);GO:0010008(endosome membrane);GO:0001875(lipopolysaccharide receptor activity);GO:0002224(toll-like receptor signaling pathway);GO:0002755(MyD88-dependent toll-like receptor signaling pathway);GO:0002756(MyD88-independent toll-like receptor signaling pathway);GO:0007249(I-kappaB kinase/NF-kappaB signaling);GO:0032496(response to lipopolysaccharide);GO:0032497(detection of lipopolysaccharide);GO:0034128(negative regulation of MyD88-independent toll-like receptor signaling pathway);GO:0034142(toll-like receptor 4 signaling pathway);GO:0035666(TRIF-dependent toll-like receptor signaling pathway);GO:0070266(necroptotic process);GO:0097190(apoptotic signaling pathway);GO:0031226(intrinsic component of plasma membrane);GO:0046696(lipopolysaccharide receptor complex);GO:0007166(cell surface receptor signaling pathway);GO:0015026(coreceptor activity);GO:0006968(cellular defense response);GO:0032760(positive regulation of tumor necrosis factor production);GO:0031663(lipopolysaccharide-mediated signaling pathway);GO:0031666(positive regulation of lipopolysaccharide-mediated signaling pathway);GO:0071222(cellular response to lipopolysaccharide);GO:0071222(cellular response to lipopolysaccharide)","04064(NF-kappa B signaling pathway);04620(Toll-like receptor signaling pathway);05130(Pathogenic Escherichia coli infection);05133(Pertussis);05145(Toxoplasmosis);05145(Toxoplasmosis)","K05400","NA","lymphocyte antigen 96 [Source:HGNC Symbol;Acc:HGNC:17156]",{"v":19.5363124917617,"d":"19.54"},{"v":41.6071804157161,"d":"41.61"},{"v":0.469541850626877,"d":"0.47"},{"v":-1.09067434275694,"d":"-1.09"},{"v":0.0416097681229684,"d":"0.04"},{"v":0.494334452856337,"d":"0.49"},"down","yes"]
["ENSG00000154188","ANGPT1","ENST00000517746;ENST00000297450;ENST00000521950;ENST00000518386;ENST00000522400","GO:0005622(intracellular);GO:0005886(plasma membrane);GO:0043547(positive regulation of GTPase activity);GO:0005576(extracellular region);GO:0007275(multicellular organism development);GO:0005615(extracellular space);GO:0001525(angiogenesis);GO:0030154(cell differentiation);GO:0045121(membrane raft);GO:0050900(leukocyte migration);GO:0030971(receptor tyrosine kinase binding);GO:0002040(sprouting angiogenesis);GO:0070062(extracellular exosome);GO:0000165(MAPK cascade);GO:0031398(positive regulation of protein ubiquitination);GO:0005902(microvillus);GO:0048014(Tie signaling pathway);GO:0043066(negative regulation of apoptotic process);GO:0070374(positive regulation of ERK1 and ERK2 cascade);GO:0043116(negative regulation of vascular permeability);GO:0005088(Ras guanyl-nucleotide exchange factor activity);GO:2000352(negative regulation of endothelial cell apoptotic process);GO:0007162(negative regulation of cell adhesion);GO:0034394(protein localization to cell surface);GO:0010595(positive regulation of endothelial cell migration);GO:0051897(positive regulation of protein kinase B signaling);GO:0072012(glomerulus vasculature development);GO:0050731(positive regulation of peptidyl-tyrosine phosphorylation);GO:0050918(positive chemotaxis);GO:0030210(heparin biosynthetic process);GO:0002092(positive regulation of receptor internalization);GO:0014842(regulation of skeletal muscle satellite cell proliferation);GO:0007171(activation of transmembrane receptor protein tyrosine kinase activity);GO:0005102(receptor binding);GO:0001701(in utero embryonic development);GO:0001933(negative regulation of protein phosphorylation);GO:0002740(negative regulation of cytokine secretion involved in immune response);GO:0007169(transmembrane receptor protein tyrosine kinase signaling pathway);GO:0014068(positive regulation of phosphatidylinositol 3-kinase signaling);GO:0030097(hemopoiesis);GO:0031589(cell-substrate adhesion);GO:0032680(regulation of tumor necrosis factor production);GO:0033138(positive regulation of peptidyl-serine phosphorylation);GO:0042308(negative regulation of protein import into nucleus);GO:0043122(regulation of I-kappaB kinase/NF-kappaB signaling);GO:0043393(regulation of protein binding);GO:0043524(negative regulation of neuron apoptotic process);GO:0043536(positive regulation of blood vessel endothelial cell migration);GO:0045785(positive regulation of cell adhesion);GO:2000446(regulation of macrophage migration inhibitory factor signaling pathway);GO:2000446(regulation of macrophage migration inhibitory factor signaling pathway)","04014(Ras signaling pathway);04015(Rap1 signaling pathway);04010(MAPK signaling pathway);04066(HIF-1 signaling pathway);04151(PI3K-Akt signaling pathway);05323(Rheumatoid arthritis);05323(Rheumatoid arthritis)","K05465","NA","angiopoietin 1 [Source:HGNC Symbol;Acc:HGNC:484]",{"v":0.296693658249158,"d":"0.30"},{"v":0.645592863496072,"d":"0.65"},{"v":0.459567747763623,"d":"0.46"},{"v":-1.12165054097246,"d":"-1.12"},{"v":0.0416281905535167,"d":"0.04"},{"v":0.494334452856337,"d":"0.49"},"down","yes"]
["MSTRG.11072","EIF4E3","ENST00000425534;ENST00000421769;ENST00000468147;ENST00000295612;ENST00000448225;ENST00000497838;ENST00000496214;ENST00000469524;ENST00000389826","GO:0003723(RNA binding);GO:0005737(cytoplasm);GO:0003743(translation initiation factor activity);GO:0006412(translation);GO:0006413(translational initiation);GO:0005829(cytosol);GO:0006417(regulation of translation);GO:0005845(mRNA cap binding complex);GO:0005845(mRNA cap binding complex)","NA","NA","NA","eukaryotic translation initiation factor 4E family member 3 [Source:HGNC Symbol;Acc:HGNC:31837]",{"v":5.85783116662028,"d":"5.86"},{"v":1.89088966991372,"d":"1.89"},{"v":3.09792330024605,"d":"3.10"},{"v":1.63130142568834,"d":"1.63"},{"v":0.0416558170757403,"d":"0.04"},{"v":0.494334452856337,"d":"0.49"},"up","yes"]
["ENSG00000149503","INCENP","ENST00000278849;ENST00000394818;ENST00000528375","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0051301(cell division);GO:0005694(chromosome);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0007049(cell cycle);GO:0016604(nuclear body);GO:0030496(midbody);GO:0005874(microtubule);GO:0005819(spindle);GO:0007059(chromosome segregation);GO:0000775(chromosome, centromeric region);GO:0000776(kinetochore);GO:0000777(condensed chromosome kinetochore);GO:0005654(nucleoplasm);GO:0043234(protein complex);GO:0007062(sister chromatid cohesion);GO:0000910(cytokinesis);GO:0016925(protein sumoylation);GO:0005721(pericentric heterochromatin);GO:0000795(synaptonemal complex);GO:0000800(lateral element);GO:0000801(central element);GO:0010369(chromocenter);GO:0010369(chromocenter)","NA","NA","NA","inner centromere protein [Source:HGNC Symbol;Acc:HGNC:6058]",{"v":2.13106304717192,"d":"2.13"},{"v":0.680695792532976,"d":"0.68"},{"v":3.13071282436153,"d":"3.13"},{"v":1.64649117827192,"d":"1.65"},{"v":0.0417142855518536,"d":"0.04"},{"v":0.494334452856337,"d":"0.49"},"up","yes"]
["MSTRG.5178","ZNF609","ENST00000326648;MSTRG.5178.1;ENST00000416172","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0007517(muscle organ development);GO:2000291(regulation of myoblast proliferation);GO:2000291(regulation of myoblast proliferation)","NA","NA","NA","zinc finger protein 609 [Source:HGNC Symbol;Acc:HGNC:29003]",{"v":4.52977720221195,"d":"4.53"},{"v":1.46674576312314,"d":"1.47"},{"v":3.08831790491537,"d":"3.09"},{"v":1.62682126822722,"d":"1.63"},{"v":0.0417159875828132,"d":"0.04"},{"v":0.494334452856337,"d":"0.49"},"up","yes"]
["MSTRG.12886","NEU1","ENST00000375631;ENST00000495807;ENST00000480384;ENST00000491768","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0004308(exo-alpha-sialidase activity);GO:0043231(intracellular membrane-bounded organelle);GO:0016787(hydrolase activity);GO:0005765(lysosomal membrane);GO:0006629(lipid metabolic process);GO:0016042(lipid catabolic process);GO:0005886(plasma membrane);GO:0030054(cell junction);GO:0005515(protein binding);GO:0008152(metabolic process);GO:0016798(hydrolase activity, acting on glycosyl bonds);GO:0031410(cytoplasmic vesicle);GO:0005975(carbohydrate metabolic process);GO:0005764(lysosome);GO:0005576(extracellular region);GO:0006687(glycosphingolipid metabolic process);GO:0070062(extracellular exosome);GO:0043312(neutrophil degranulation);GO:0035580(specific granule lumen);GO:0043202(lysosomal lumen);GO:0052794(exo-alpha-(2->3)-sialidase activity);GO:0052795(exo-alpha-(2->6)-sialidase activity);GO:0052796(exo-alpha-(2->8)-sialidase activity);GO:0009313(oligosaccharide catabolic process);GO:0006689(ganglioside catabolic process);GO:0006689(ganglioside catabolic process)","00600(Sphingolipid metabolism);00511(Other glycan degradation);04142(Lysosome);04142(Lysosome)","K01186","EC:3.2.1.18","neuraminidase 1 [Source:HGNC Symbol;Acc:HGNC:7758]",{"v":3.04492695396101,"d":"3.04"},{"v":6.47456609767731,"d":"6.47"},{"v":0.470290504108584,"d":"0.47"},{"v":-1.08837589263781,"d":"-1.09"},{"v":0.0417789778639064,"d":"0.04"},{"v":0.494472064525711,"d":"0.49"},"down","yes"]
["MSTRG.4704","C14orf2","ENST00000286953;ENST00000555030;ENST00000554089;ENST00000554880;ENST00000553430;ENST00000554287;ENST00000554528;ENST00000414262;ENST00000557260;ENST00000553449;ENST00000557040","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005739(mitochondrion);GO:0031966(mitochondrial membrane);GO:0003674(molecular_function);GO:0008150(biological_process);GO:0005575(cellular_component);GO:0005753(mitochondrial proton-transporting ATP synthase complex);GO:0005753(mitochondrial proton-transporting ATP synthase complex)","NA","NA","NA","chromosome 14 open reading frame 2 [Source:HGNC Symbol;Acc:HGNC:1188]",{"v":4.82221451420205,"d":"4.82"},{"v":10.2842294450952,"d":"10.28"},{"v":0.46889410042304,"d":"0.47"},{"v":-1.09266596755387,"d":"-1.09"},{"v":0.0418695332118074,"d":"0.04"},{"v":0.494472064525711,"d":"0.49"},"down","yes"]
["MSTRG.11680","ANXA3","ENST00000264908;ENST00000503776;ENST00000510502;ENST00000512542;ENST00000505805;ENST00000503570;MSTRG.11680.10;ENST00000512884;ENST00000508214","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005829(cytosol);GO:0005509(calcium ion binding);GO:0005886(plasma membrane);GO:0043086(negative regulation of catalytic activity);GO:0004859(phospholipase inhibitor activity);GO:0005544(calcium-dependent phospholipid binding);GO:0042742(defense response to bacterium);GO:0070062(extracellular exosome);GO:0030670(phagocytic vesicle membrane);GO:0042581(specific granule);GO:0043312(neutrophil degranulation);GO:0006909(phagocytosis);GO:0051091(positive regulation of sequence-specific DNA binding transcription factor activity);GO:0045766(positive regulation of angiogenesis);GO:0010595(positive regulation of endothelial cell migration);GO:0048306(calcium-dependent protein binding);GO:0019834(phospholipase A2 inhibitor activity);GO:0021766(hippocampus development);GO:0031100(animal organ regeneration);GO:0051054(positive regulation of DNA metabolic process);GO:0051384(response to glucocorticoid);GO:0070848(response to growth factor);GO:0030424(axon);GO:0030425(dendrite);GO:0043025(neuronal cell body);GO:0043025(neuronal cell body)","NA","NA","NA","annexin A3 [Source:HGNC Symbol;Acc:HGNC:541]",{"v":5.19740524787561,"d":"5.20"},{"v":11.0467376185138,"d":"11.05"},{"v":0.470492323377448,"d":"0.47"},{"v":-1.08775691096785,"d":"-1.09"},{"v":0.041889580195142,"d":"0.04"},{"v":0.494472064525711,"d":"0.49"},"down","yes"]
["ENSG00000257923","CUX1","ENST00000360264;ENST00000622516;ENST00000292538;ENST00000437600;ENST00000558469;ENST00000465461;ENST00000547394;ENST00000425244;ENST00000485792;ENST00000558836;ENST00000560541;ENST00000292535;ENST00000487284;ENST00000546411;ENST00000549414","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005794(Golgi apparatus);GO:0005654(nucleoplasm);GO:0000139(Golgi membrane);GO:0006891(intra-Golgi vesicle-mediated transport);GO:0030173(integral component of Golgi membrane);GO:0005634(nucleus);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0018108(peptidyl-tyrosine phosphorylation);GO:0043565(sequence-specific DNA binding);GO:0007275(multicellular organism development);GO:0005829(cytosol);GO:0000977(RNA polymerase II regulatory region sequence-specific DNA binding);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0004713(protein tyrosine kinase activity);GO:0048193(Golgi vesicle transport);GO:0050775(positive regulation of dendrite morphogenesis);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0030674(protein binding, bridging);GO:0000301(retrograde transport, vesicle recycling within Golgi);GO:0000301(retrograde transport, vesicle recycling within Golgi)","NA","NA","NA","cut like homeobox 1 [Source:HGNC Symbol;Acc:HGNC:2557]",{"v":4.28376123841916,"d":"4.28"},{"v":1.38819606313245,"d":"1.39"},{"v":3.08584741895385,"d":"3.09"},{"v":1.62566672899851,"d":"1.63"},{"v":0.0418979171181692,"d":"0.04"},{"v":0.494472064525711,"d":"0.49"},"up","yes"]
["MSTRG.12942","HSD17B8","ENST00000374662;ENST00000469186","GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0006629(lipid metabolic process);GO:0006631(fatty acid metabolic process);GO:0006633(fatty acid biosynthetic process);GO:0005739(mitochondrion);GO:0006694(steroid biosynthetic process);GO:0005759(mitochondrial matrix);GO:0005515(protein binding);GO:0004303(estradiol 17-beta-dehydrogenase activity);GO:0047035(testosterone dehydrogenase (NAD+) activity);GO:0008209(androgen metabolic process);GO:0008210(estrogen metabolic process);GO:0005740(mitochondrial envelope);GO:0005886(plasma membrane);GO:0016020(membrane);GO:0046949(fatty-acyl-CoA biosynthetic process);GO:0051290(protein heterotetramerization);GO:0006703(estrogen biosynthetic process);GO:0003857(3-hydroxyacyl-CoA dehydrogenase activity);GO:0070404(NADH binding);GO:0047025(3-oxoacyl-[acyl-carrier-protein] reductase (NADH) activity);GO:0047025(3-oxoacyl-[acyl-carrier-protein] reductase (NADH) activity)","00140(Steroid hormone biosynthesis);00140(Steroid hormone biosynthesis)","K13370","EC:1.1.1.62;EC:1.1.1.239","hydroxysteroid 17-beta dehydrogenase 8 [Source:HGNC Symbol;Acc:HGNC:3554]",{"v":1.4089496823228,"d":"1.41"},{"v":3.08580775747225,"d":"3.09"},{"v":0.456590232787847,"d":"0.46"},{"v":-1.13102809660213,"d":"-1.13"},{"v":0.0420364329093198,"d":"0.04"},{"v":0.495603142513635,"d":"0.50"},"down","yes"]
["ENSG00000124177","CHD6","ENST00000373233;ENST00000480022;ENST00000482596;ENST00000476641;ENST00000373222;ENST00000470470;ENST00000440647","GO:0005634(nucleus);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0016787(hydrolase activity);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0016569(covalent chromatin modification);GO:0004386(helicase activity);GO:0003677(DNA binding);GO:0005654(nucleoplasm);GO:0016817(hydrolase activity, acting on acid anhydrides);GO:0008094(DNA-dependent ATPase activity);GO:0005665(DNA-directed RNA polymerase II, core complex);GO:0036091(positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress);GO:0001221(transcription cofactor binding);GO:0001221(transcription cofactor binding)","NA","NA","NA","chromodomain helicase DNA binding protein 6 [Source:HGNC Symbol;Acc:HGNC:19057]",{"v":3.19575473233753,"d":"3.20"},{"v":1.03489978698853,"d":"1.03"},{"v":3.08798472327152,"d":"3.09"},{"v":1.62666561539261,"d":"1.63"},{"v":0.0422141919190651,"d":"0.04"},{"v":0.496775717702592,"d":"0.50"},"up","yes"]
["MSTRG.5619","MGRN1","ENST00000262370;ENST00000415496;ENST00000591673;ENST00000399577;ENST00000591895;ENST00000590790;ENST00000586183;ENST00000588994;ENST00000592256;ENST00000593224;ENST00000536343;ENST00000588111;ENST00000588015;ENST00000590457;ENST00000615397;ENST00000585676;ENST00000587747","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0046872(metal ion binding);GO:0016740(transferase activity);GO:0016567(protein ubiquitination);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0005768(endosome);GO:0070062(extracellular exosome);GO:0008333(endosome to lysosome transport);GO:0005769(early endosome);GO:0004842(ubiquitin-protein transferase activity);GO:0006513(protein monoubiquitination);GO:0061630(ubiquitin protein ligase activity);GO:0000209(protein polyubiquitination);GO:0043951(negative regulation of cAMP-mediated signaling);GO:0045744(negative regulation of G-protein coupled receptor protein signaling pathway);GO:0016874(ligase activity);GO:0016874(ligase activity)","04120(Ubiquitin mediated proteolysis);04120(Ubiquitin mediated proteolysis)","K10604","EC:2.3.2.27","mahogunin ring finger 1 [Source:HGNC Symbol;Acc:HGNC:20254]",{"v":6.07478732459145,"d":"6.07"},{"v":1.97215094686369,"d":"1.97"},{"v":3.08028517505325,"d":"3.08"},{"v":1.62306392286489,"d":"1.62"},{"v":0.0422382754769525,"d":"0.04"},{"v":0.496775717702592,"d":"0.50"},"up","yes"]
["ENSG00000223459","TCAF1P1","ENST00000414990","NA","NA","NA","NA","TRPM8 channel associated factor 1 pseudogene 1 [Source:HGNC Symbol;Acc:HGNC:33604]",{"v":1.257634,"d":"1.26"},{"v":0.385239,"d":"0.39"},{"v":3.26455525011746,"d":"3.26"},{"v":1.70688645818668,"d":"1.71"},{"v":0.0422642219142479,"d":"0.04"},{"v":0.496775717702592,"d":"0.50"},"up","yes"]
["MSTRG.5507","TMEM204","ENST00000566264;ENST00000253934","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005886(plasma membrane);GO:0030054(cell junction);GO:0005912(adherens junction);GO:0001945(lymph vessel development);GO:0030947(regulation of vascular endothelial growth factor receptor signaling pathway);GO:0051145(smooth muscle cell differentiation);GO:0051145(smooth muscle cell differentiation)","NA","NA","NA","transmembrane protein 204 [Source:HGNC Symbol;Acc:HGNC:14158]",{"v":3.92090723595506,"d":"3.92"},{"v":8.36306680214949,"d":"8.36"},{"v":0.468836053652866,"d":"0.47"},{"v":-1.09284457711914,"d":"-1.09"},{"v":0.0423204662356753,"d":"0.04"},{"v":0.496933846708693,"d":"0.50"},"down","yes"]
["MSTRG.237","HMGCL","ENST00000374490;ENST00000509389;ENST00000374487;ENST00000496907;ENST00000436439;ENST00000479458;ENST00000498698;ENST00000513148","GO:0046872(metal ion binding);GO:0003824(catalytic activity);GO:0016829(lyase activity);GO:0005739(mitochondrion);GO:0042803(protein homodimerization activity);GO:0000287(magnesium ion binding);GO:0005759(mitochondrial matrix);GO:0005777(peroxisome);GO:0005102(receptor binding);GO:0004419(hydroxymethylglutaryl-CoA lyase activity);GO:0046951(ketone body biosynthetic process);GO:0051262(protein tetramerization);GO:0006629(lipid metabolic process);GO:0030145(manganese ion binding);GO:0006552(leucine catabolic process);GO:0000062(fatty-acyl-CoA binding);GO:0031406(carboxylic acid binding);GO:0001889(liver development);GO:0006637(acyl-CoA metabolic process);GO:0007005(mitochondrion organization);GO:0007584(response to nutrient);GO:0042594(response to starvation);GO:0070542(response to fatty acid);GO:0005743(mitochondrial inner membrane);GO:0005743(mitochondrial inner membrane)","00650(Butanoate metabolism);00072(Synthesis and degradation of ketone bodies);00280(Valine, leucine and isoleucine degradation);04146(Peroxisome);04146(Peroxisome)","K01640","EC:4.1.3.4","3-hydroxymethyl-3-methylglutaryl-CoA lyase [Source:HGNC Symbol;Acc:HGNC:5005]",{"v":1.1625867368328,"d":"1.16"},{"v":2.47715660993284,"d":"2.48"},{"v":0.469323066685041,"d":"0.47"},{"v":-1.09134672598866,"d":"-1.09"},{"v":0.042410802917281,"d":"0.04"},{"v":0.497473367712964,"d":"0.50"},"down","yes"]
["MSTRG.2515","CCDC88B","ENST00000356786;ENST00000494566;ENST00000463837;ENST00000473405;MSTRG.2515.1;ENST00000472524;ENST00000492980;ENST00000301897;MSTRG.2515.8;ENST00000494080;ENST00000479965;ENST00000359902","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005794(Golgi apparatus);GO:0005783(endoplasmic reticulum);GO:0005856(cytoskeleton);GO:0005813(centrosome);GO:0008017(microtubule binding);GO:0051959(dynein light intermediate chain binding);GO:0001819(positive regulation of cytokine production);GO:0030705(cytoskeleton-dependent intracellular transport);GO:0031122(cytoplasmic microtubule organization);GO:0042102(positive regulation of T cell proliferation);GO:0042832(defense response to protozoan);GO:0050870(positive regulation of T cell activation);GO:0050870(positive regulation of T cell activation)","NA","NA","NA","coiled-coil domain containing 88B [Source:HGNC Symbol;Acc:HGNC:26757]",{"v":14.6982005327203,"d":"14.70"},{"v":4.77717069226176,"d":"4.78"},{"v":3.07675849986457,"d":"3.08"},{"v":1.62141120846798,"d":"1.62"},{"v":0.0424803516498742,"d":"0.04"},{"v":0.497473367712964,"d":"0.50"},"up","yes"]
["MSTRG.14431","OSGIN2","ENST00000451899;ENST00000520659;ENST00000297438","GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0051321(meiotic cell cycle);GO:0003674(molecular_function);GO:0005575(cellular_component);GO:0008083(growth factor activity);GO:0030308(negative regulation of cell growth);GO:0030308(negative regulation of cell growth)","NA","NA","NA","oxidative stress induced growth inhibitor family member 2 [Source:HGNC Symbol;Acc:HGNC:1355]",{"v":2.05739810745567,"d":"2.06"},{"v":4.37035350160222,"d":"4.37"},{"v":0.47076240095942,"d":"0.47"},{"v":-1.08692899565696,"d":"-1.09"},{"v":0.042494926442027,"d":"0.04"},{"v":0.497473367712964,"d":"0.50"},"down","yes"]
["MSTRG.6975","SP2","ENST00000376741;MSTRG.6975.4;ENST00000642065;ENST00000637943;ENST00000635868;ENST00000613139","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0035264(multicellular organism growth);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:0001078(transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0006955(immune response);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0042826(histone deacetylase binding);GO:0042826(histone deacetylase binding)","NA","NA","NA","Sp2 transcription factor [Source:HGNC Symbol;Acc:HGNC:11207]",{"v":9.95205353761669,"d":"9.95"},{"v":3.23016595332235,"d":"3.23"},{"v":3.08097282970264,"d":"3.08"},{"v":1.62338595968135,"d":"1.62"},{"v":0.0426590177159894,"d":"0.04"},{"v":0.497727832443382,"d":"0.50"},"up","yes"]
["ENSG00000099904","ZDHHC8","ENST00000334554;ENST00000468112;ENST00000469212;ENST00000436518;ENST00000472497","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016740(transferase activity);GO:0016746(transferase activity, transferring acyl groups);GO:0019706(protein-cysteine S-palmitoyltransferase activity);GO:0016409(palmitoyltransferase activity);GO:0018345(protein palmitoylation);GO:0005794(Golgi apparatus);GO:0030659(cytoplasmic vesicle membrane);GO:0031410(cytoplasmic vesicle);GO:0005829(cytosol);GO:1903146(regulation of mitophagy);GO:1903955(positive regulation of protein targeting to mitochondrion);GO:0034380(high-density lipoprotein particle assembly);GO:0007626(locomotory behavior);GO:0005739(mitochondrion);GO:0005739(mitochondrion)","NA","NA","NA","zinc finger DHHC-type containing 8 [Source:HGNC Symbol;Acc:HGNC:18474]",{"v":1.93707279357633,"d":"1.94"},{"v":0.622060163839769,"d":"0.62"},{"v":3.11396373884389,"d":"3.11"},{"v":1.6387521447719,"d":"1.64"},{"v":0.042672946428306,"d":"0.04"},{"v":0.497727832443382,"d":"0.50"},"up","yes"]
["MSTRG.15321","MAGED2","ENST00000375068;ENST00000375058;ENST00000218439;ENST00000375053;ENST00000485483;ENST00000487463;ENST00000375060;ENST00000396224;ENST00000487482;ENST00000627068;ENST00000497484;ENST00000347546","GO:0016020(membrane);GO:0005634(nucleus);GO:0005730(nucleolus);GO:0005829(cytosol);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0070294(renal sodium ion absorption);GO:0007565(female pregnancy);GO:0002576(platelet degranulation);GO:0031093(platelet alpha granule lumen);GO:0031093(platelet alpha granule lumen)","NA","NA","NA","MAGE family member D2 [Source:HGNC Symbol;Acc:HGNC:16353]",{"v":8.1759460877551,"d":"8.18"},{"v":17.3099565421769,"d":"17.31"},{"v":0.472326205316221,"d":"0.47"},{"v":-1.0821445144466,"d":"-1.08"},{"v":0.0426953162545842,"d":"0.04"},{"v":0.497727832443382,"d":"0.50"},"down","yes"]
["MSTRG.12683","JARID2","ENST00000397311;ENST00000341776;ENST00000474854","GO:0005634(nucleus);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0016569(covalent chromatin modification);GO:0005739(mitochondrion);GO:0003677(DNA binding);GO:0007275(multicellular organism development);GO:0030154(cell differentiation);GO:0005654(nucleoplasm);GO:0003682(chromatin binding);GO:0035098(ESC/E(Z) complex);GO:0048863(stem cell differentiation);GO:0007417(central nervous system development);GO:0045892(negative regulation of transcription, DNA-templated);GO:0035097(histone methyltransferase complex);GO:0045814(negative regulation of gene expression, epigenetic);GO:0051574(positive regulation of histone H3-K9 methylation);GO:0000977(RNA polymerase II regulatory region sequence-specific DNA binding);GO:0001227(transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding);GO:0008134(transcription factor binding);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0001889(liver development);GO:0008285(negative regulation of cell proliferation);GO:0010614(negative regulation of cardiac muscle hypertrophy);GO:0031061(negative regulation of histone methylation);GO:0042127(regulation of cell proliferation);GO:0048536(spleen development);GO:0048538(thymus development);GO:0060044(negative regulation of cardiac muscle cell proliferation);GO:1990830(cellular response to leukemia inhibitory factor);GO:1990830(cellular response to leukemia inhibitory factor)","04550(Signaling pathways regulating pluripotency of stem cells);04550(Signaling pathways regulating pluripotency of stem cells)","K11478","NA","jumonji and AT-rich interaction domain containing 2 [Source:HGNC Symbol;Acc:HGNC:6196]",{"v":13.7197131221945,"d":"13.72"},{"v":4.46604104322527,"d":"4.47"},{"v":3.07200784529433,"d":"3.07"},{"v":1.61918190041869,"d":"1.62"},{"v":0.0427252202723794,"d":"0.04"},{"v":0.497727832443382,"d":"0.50"},"up","yes"]
["MSTRG.1423","EPHX1","MSTRG.1423.1;ENST00000272167;ENST00000467015;ENST00000614058;ENST00000448202","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016787(hydrolase activity);GO:0003824(catalytic activity);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0043231(intracellular membrane-bounded organelle);GO:0006805(xenobiotic metabolic process);GO:0031090(organelle membrane);GO:0009636(response to toxic substance);GO:0004301(epoxide hydrolase activity);GO:0033961(cis-stilbene-oxide hydrolase activity);GO:0019439(aromatic compound catabolic process);GO:0019899(enzyme binding);GO:0001889(liver development);GO:0006725(cellular aromatic compound metabolic process);GO:0014070(response to organic cyclic compound);GO:0034312(diol biosynthetic process);GO:0071310(cellular response to organic substance);GO:0071385(cellular response to glucocorticoid stimulus);GO:0005886(plasma membrane);GO:0005886(plasma membrane)","00980(Metabolism of xenobiotics by cytochrome P450);04976(Bile secretion);05204(Chemical carcinogenesis);05204(Chemical carcinogenesis)","K01253","EC:3.3.2.9","epoxide hydrolase 1 [Source:HGNC Symbol;Acc:HGNC:3401]",{"v":5.35741754057692,"d":"5.36"},{"v":1.73312143192308,"d":"1.73"},{"v":3.09119571306224,"d":"3.09"},{"v":1.62816499852671,"d":"1.63"},{"v":0.0427309609012359,"d":"0.04"},{"v":0.497727832443382,"d":"0.50"},"up","yes"]
["MSTRG.8022","NDUFA13;AC011448.1;YJEFN3","ENST00000428459;ENST00000507754;ENST00000511180;ENST00000502506;ENST00000606722;ENST00000555938;ENST00000511584;ENST00000503283;ENST00000586674;ENST00000458210","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005524(ATP binding);GO:0055114(oxidation-reduction process);GO:0005739(mitochondrion);GO:0005743(mitochondrial inner membrane);GO:0005515(protein binding);GO:0006915(apoptotic process);GO:0070469(respiratory chain);GO:0005654(nucleoplasm);GO:0031966(mitochondrial membrane);GO:0070062(extracellular exosome);GO:0032981(mitochondrial respiratory chain complex I assembly);GO:0003954(NADH dehydrogenase activity);GO:0008137(NADH dehydrogenase (ubiquinone) activity);GO:0030308(negative regulation of cell growth);GO:0006120(mitochondrial electron transport, NADH to ubiquinone);GO:0005747(mitochondrial respiratory chain complex I);GO:0045892(negative regulation of transcription, DNA-templated);GO:0097190(apoptotic signaling pathway);GO:2001243(negative regulation of intrinsic apoptotic signaling pathway);GO:0072593(reactive oxygen species metabolic process);GO:0035458(cellular response to interferon-beta);GO:0043280(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process);GO:0071300(cellular response to retinoic acid);GO:0045732(positive regulation of protein catabolic process);GO:0010952(positive regulation of peptidase activity);GO:0005746(mitochondrial respiratory chain);GO:0045039(protein import into mitochondrial inner membrane);GO:0097191(extrinsic apoptotic signaling pathway);GO:0016021(integral component of membrane)","00190(Oxidative phosphorylation);04723(Retrograde endocannabinoid signaling);05010(Alzheimer's disease);05012(Parkinson's disease);05016(Huntington's disease);04932(Non-alcoholic fatty liver disease (NAFLD));04932(Non-alcoholic fatty liver disease (NAFLD))","K11353","NA","NADH:ubiquinone oxidoreductase subunit A13 [Source:HGNC Symbol;Acc:HGNC:17194];YjeF N-terminal domain containing 3 [Source:HGNC Symbol;Acc:HGNC:24785]",{"v":3.29235181994273,"d":"3.29"},{"v":6.96159896378642,"d":"6.96"},{"v":0.47293040536653,"d":"0.47"},{"v":-1.08030019719952,"d":"-1.08"},{"v":0.042795333520416,"d":"0.04"},{"v":0.497801737252677,"d":"0.50"},"down","yes"]
["MSTRG.1338","ELK4","ENST00000357992;ENST00000616704;ENST00000468523;ENST00000289703;MSTRG.1338.1","GO:0005634(nucleus);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0006355(regulation of transcription, DNA-templated);GO:0006366(transcription from RNA polymerase II promoter);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0043565(sequence-specific DNA binding);GO:0005515(protein binding);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:0001047(core promoter binding);GO:0003682(chromatin binding);GO:0000981(RNA polymerase II transcription factor activity, sequence-specific DNA binding);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0030154(cell differentiation);GO:0003712(transcription cofactor activity);GO:0001077(transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0070932(histone H3 deacetylation);GO:0070932(histone H3 deacetylation)","04010(MAPK signaling pathway);05202(Transcriptional misregulation in cancers);05166(HTLV-I infection);05166(HTLV-I infection)","K04376","NA","ELK4, ETS transcription factor [Source:HGNC Symbol;Acc:HGNC:3326]",{"v":5.75788954385822,"d":"5.76"},{"v":1.87491883738974,"d":"1.87"},{"v":3.07100735724345,"d":"3.07"},{"v":1.61871196859706,"d":"1.62"},{"v":0.0428230375885149,"d":"0.04"},{"v":0.497801737252677,"d":"0.50"},"up","yes"]
["MSTRG.9573","CDC25B","ENST00000344256;ENST00000439880;ENST00000467519;ENST00000245960;ENST00000468979;ENST00000495915;ENST00000480816","GO:0005737(cytoplasm);GO:0016787(hydrolase activity);GO:0005622(intracellular);GO:0051301(cell division);GO:0004725(protein tyrosine phosphatase activity);GO:0006470(protein dephosphorylation);GO:0035335(peptidyl-tyrosine dephosphorylation);GO:0004721(phosphoprotein phosphatase activity);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0007049(cell cycle);GO:1902751(positive regulation of cell cycle G2/M phase transition);GO:0000922(spindle pole);GO:0005813(centrosome);GO:0005815(microtubule organizing center);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0019901(protein kinase binding);GO:0000086(G2/M transition of mitotic cell cycle);GO:0006468(protein phosphorylation);GO:0000278(mitotic cell cycle);GO:0032467(positive regulation of cytokinesis);GO:0008284(positive regulation of cell proliferation);GO:0045931(positive regulation of mitotic cell cycle);GO:0001556(oocyte maturation);GO:0007144(female meiosis I);GO:0045860(positive regulation of protein kinase activity);GO:0005634(nucleus);GO:0005634(nucleus)","04010(MAPK signaling pathway);04110(Cell cycle);04914(Progesterone-mediated oocyte maturation);05206(MicroRNAs in cancer);05206(MicroRNAs in cancer)","K05866","EC:3.1.3.48","cell division cycle 25B [Source:HGNC Symbol;Acc:HGNC:1726]",{"v":16.3900865711637,"d":"16.39"},{"v":5.33991042280946,"d":"5.34"},{"v":3.06935608903725,"d":"3.07"},{"v":1.61793602869365,"d":"1.62"},{"v":0.0430461667196347,"d":"0.04"},{"v":0.499895134115118,"d":"0.50"},"up","yes"]
["MSTRG.7262","SEC14L1;SNHG20","ENST00000436233;ENST00000443798;ENST00000434411;ENST00000564509;ENST00000591786;ENST00000588880;ENST00000590483;ENST00000588696;ENST00000587821;ENST00000586390;ENST00000589202;ENST00000587491;ENST00000392476;ENST00000586429;ENST00000431431;ENST00000561633;ENST00000561721;ENST00000585618;ENST00000589827;ENST00000588721;ENST00000366365;ENST00000587820;ENST00000430767;ENST00000588616;ENST00000591413;ENST00000591437;ENST00000588488","GO:0005737(cytoplasm);GO:0016021(integral component of membrane);GO:0006810(transport);GO:0005794(Golgi apparatus);GO:0065009(regulation of molecular function);GO:0002376(immune system process);GO:0045087(innate immune response);GO:0005515(protein binding);GO:0009968(negative regulation of signal transduction);GO:0039536(negative regulation of RIG-I signaling pathway);GO:0015871(choline transport);GO:0039552(RIG-I binding);GO:0098772(molecular function regulator);GO:0098772(molecular function regulator)","NA","NA","NA","SEC14 like lipid binding 1 [Source:HGNC Symbol;Acc:HGNC:10698];small nucleolar RNA host gene 20 [Source:HGNC Symbol;Acc:HGNC:33099]",{"v":34.4661548070319,"d":"34.47"},{"v":11.2542554464766,"d":"11.25"},{"v":3.06249977805705,"d":"3.06"},{"v":1.61470973956141,"d":"1.61"},{"v":0.0430945114294925,"d":"0.04"},{"v":0.49995660462607,"d":"0.50"},"up","yes"]
["MSTRG.14617","MROH6","ENST00000533679;ENST00000533083;ENST00000529971;ENST00000533210;ENST00000534459;ENST00000398882","NA","NA","NA","NA","maestro heat like repeat family member 6 [Source:HGNC Symbol;Acc:HGNC:27814]",{"v":0.596696222776769,"d":"0.60"},{"v":0.182470783348457,"d":"0.18"},{"v":3.27009185704696,"d":"3.27"},{"v":1.70933116166979,"d":"1.71"},{"v":0.0431548258908719,"d":"0.04"},{"v":0.500156679711273,"d":"0.50"},"up","yes"]
["MSTRG.11834","KIAA1109","ENST00000306802;ENST00000264501;ENST00000424425;ENST00000442707;ENST00000438707;ENST00000446180;ENST00000470182;ENST00000480651;ENST00000419325;ENST00000483357;ENST00000491933;ENST00000388738;ENST00000482114;ENST00000449251","GO:0005634(nucleus);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005515(protein binding);GO:0001558(regulation of cell growth);GO:0030856(regulation of epithelial cell differentiation);GO:0030856(regulation of epithelial cell differentiation)","NA","NA","NA","KIAA1109 [Source:HGNC Symbol;Acc:HGNC:26953]",{"v":5.92146479535906,"d":"5.92"},{"v":1.93363298597948,"d":"1.93"},{"v":3.06235197594105,"d":"3.06"},{"v":1.61464011065009,"d":"1.61"},{"v":0.0433719766752517,"d":"0.04"},{"v":0.502020905259627,"d":"0.50"},"up","yes"]
["MSTRG.11473","RUBCN","ENST00000296343;ENST00000474214;ENST00000415452;ENST00000273582;ENST00000449205;ENST00000472149;ENST00000471364","GO:0043231(intracellular membrane-bounded organelle);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0005515(protein binding);GO:0006914(autophagy);GO:0002376(immune system process);GO:0005764(lysosome);GO:0005768(endosome);GO:0006897(endocytosis);GO:0005769(early endosome);GO:0005770(late endosome);GO:0006909(phagocytosis);GO:0010507(negative regulation of autophagy);GO:1901097(negative regulation of autophagosome maturation);GO:0043553(negative regulation of phosphatidylinositol 3-kinase activity);GO:0045806(negative regulation of endocytosis);GO:0071985(multivesicular body sorting pathway);GO:0071985(multivesicular body sorting pathway)","04140(Autophagy - animal);04140(Autophagy - animal)","K19330","NA","RUN and cysteine rich domain containing beclin 1 interacting protein [Source:HGNC Symbol;Acc:HGNC:28991]",{"v":2.42914346940671,"d":"2.43"},{"v":0.789122006153489,"d":"0.79"},{"v":3.07828631119714,"d":"3.08"},{"v":1.62212742287286,"d":"1.62"},{"v":0.0434182193459191,"d":"0.04"},{"v":0.502020905259627,"d":"0.50"},"up","yes"]
["MSTRG.1908","BLOC1S2","ENST00000370372;ENST00000614731;ENST00000441611;ENST00000361832;ENST00000618916;ENST00000579542","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005765(lysosomal membrane);GO:1904115(axon cytoplasm);GO:0005739(mitochondrion);GO:0055114(oxidation-reduction process);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0005764(lysosome);GO:0005815(microtubule organizing center);GO:0016491(oxidoreductase activity);GO:0008089(anterograde axonal transport);GO:0032438(melanosome organization);GO:0048490(anterograde synaptic vesicle transport);GO:0008625(extrinsic apoptotic signaling pathway via death domain receptors);GO:0031175(neuron projection development);GO:0043015(gamma-tubulin binding);GO:0032418(lysosome localization);GO:0031083(BLOC-1 complex);GO:0099078(BORC complex);GO:0000930(gamma-tubulin complex);GO:0060155(platelet dense granule organization);GO:0097345(mitochondrial outer membrane permeabilization);GO:0005829(cytosol);GO:0005829(cytosol)","NA","NA","NA","biogenesis of lysosomal organelles complex 1 subunit 2 [Source:HGNC Symbol;Acc:HGNC:20984]",{"v":3.7856085572545,"d":"3.79"},{"v":8.0146378504927,"d":"8.01"},{"v":0.4723368201873,"d":"0.47"},{"v":-1.08211209225699,"d":"-1.08"},{"v":0.0434598527280285,"d":"0.04"},{"v":0.502020905259627,"d":"0.50"},"down","yes"]
["ENSG00000137075","RNF38","ENST00000353739;ENST00000350199;ENST00000377885;ENST00000611646;ENST00000491349;ENST00000377877;ENST00000484621;ENST00000259605;ENST00000357058;ENST00000488058","GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0005654(nucleoplasm);GO:0016740(transferase activity);GO:0016567(protein ubiquitination);GO:0061630(ubiquitin protein ligase activity);GO:0043161(proteasome-mediated ubiquitin-dependent protein catabolic process);GO:0004842(ubiquitin-protein transferase activity);GO:0008584(male gonad development);GO:0036126(sperm flagellum);GO:0036126(sperm flagellum)","NA","NA","NA","ring finger protein 38 [Source:HGNC Symbol;Acc:HGNC:18052]",{"v":10.0374207279244,"d":"10.04"},{"v":3.27532777077224,"d":"3.28"},{"v":3.06455458213815,"d":"3.06"},{"v":1.61567740055956,"d":"1.62"},{"v":0.043488593015688,"d":"0.04"},{"v":0.502020905259627,"d":"0.50"},"up","yes"]
["ENSG00000131437","KIF3A","ENST00000488471;ENST00000618515;ENST00000378735;ENST00000378746;ENST00000487055;ENST00000450441;ENST00000403231","GO:0005737(cytoplasm);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0003777(microtubule motor activity);GO:0005856(cytoskeleton);GO:0042995(cell projection);GO:0005515(protein binding);GO:0008017(microtubule binding);GO:0005874(microtubule);GO:0007018(microtubule-based movement);GO:0035735(intraciliary transport involved in cilium assembly);GO:0060271(cilium assembly);GO:0005929(cilium);GO:0097542(ciliary tip);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0030030(cell projection organization);GO:0005814(centriole);GO:0006890(retrograde vesicle-mediated transport, Golgi to ER);GO:0019886(antigen processing and presentation of exogenous peptide antigen via MHC class II);GO:0017137(Rab GTPase binding);GO:0030507(spectrin binding);GO:0005876(spindle microtubule);GO:0015630(microtubule cytoskeleton);GO:0005813(centrosome);GO:0072383(plus-end-directed vesicle transport along microtubule);GO:0016939(kinesin II complex);GO:0006996(organelle organization);GO:0022008(neurogenesis);GO:0010457(centriole-centriole cohesion);GO:0034454(microtubule anchoring at centrosome);GO:0008574(ATP-dependent microtubule motor activity, plus-end-directed);GO:0003774(motor activity);GO:0019894(kinesin binding);GO:0032403(protein complex binding);GO:0001701(in utero embryonic development);GO:0001822(kidney development);GO:0001947(heart looping);GO:0007224(smoothened signaling pathway);GO:0007368(determination of left/right symmetry);GO:0007507(heart development);GO:0008544(epidermis development);GO:0009952(anterior/posterior pattern specification);GO:0009953(dorsal/ventral pattern formation);GO:0021542(dentate gyrus development);GO:0021904(dorsal/ventral neural tube patterning);GO:0021915(neural tube development);GO:0036334(epidermal stem cell homeostasis);GO:0044458(motile cilium assembly);GO:0048260(positive regulation of receptor-mediated endocytosis);GO:0050679(positive regulation of epithelial cell proliferation);GO:0060122(inner ear receptor stereocilium organization);GO:0061351(neural precursor cell proliferation);GO:0090316(positive regulation of intracellular protein transport);GO:1905128(positive regulation of axo-dendritic protein transport);GO:1905515(non-motile cilium assembly);GO:2000771(positive regulation of establishment or maintenance of cell polarity regulating cell shape);GO:0005930(axoneme);GO:0030990(intraciliary transport particle);GO:0031514(motile cilium);GO:0032391(photoreceptor connecting cilium);GO:0043005(neuron projection);GO:0043025(neuronal cell body);GO:0097470(ribbon synapse);GO:1904115(axon cytoplasm);GO:1904115(axon cytoplasm)","04340(Hedgehog signaling pathway);04340(Hedgehog signaling pathway)","K10394","NA","kinesin family member 3A [Source:HGNC Symbol;Acc:HGNC:6319]",{"v":0.883320845335277,"d":"0.88"},{"v":0.281975587463557,"d":"0.28"},{"v":3.13261461136042,"d":"3.13"},{"v":1.64736729365456,"d":"1.65"},{"v":0.0435504806957388,"d":"0.04"},{"v":0.502236079761286,"d":"0.50"},"up","yes"]
["MSTRG.15201","PRDX4","ENST00000379341;ENST00000379349;ENST00000439422","GO:0005623(cell);GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0045454(cell redox homeostasis);GO:0098869(cellular oxidant detoxification);GO:0016209(antioxidant activity);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0004601(peroxidase activity);GO:0051920(peroxiredoxin activity);GO:0070062(extracellular exosome);GO:0043312(neutrophil degranulation);GO:0034774(secretory granule lumen);GO:1904813(ficolin-1-rich granule lumen);GO:0007252(I-kappaB phosphorylation);GO:0008379(thioredoxin peroxidase activity);GO:0042803(protein homodimerization activity);GO:0007283(spermatogenesis);GO:0008584(male gonad development);GO:0019471(4-hydroxyproline metabolic process);GO:0022417(protein maturation by protein folding);GO:0030198(extracellular matrix organization);GO:0072593(reactive oxygen species metabolic process);GO:2000255(negative regulation of male germ cell proliferation);GO:0005615(extracellular space);GO:0005739(mitochondrion);GO:0005783(endoplasmic reticulum);GO:0005790(smooth endoplasmic reticulum);GO:0005829(cytosol);GO:0005829(cytosol)","NA","NA","NA","peroxiredoxin 4 [Source:HGNC Symbol;Acc:HGNC:17169]",{"v":2.20756804254202,"d":"2.21"},{"v":4.71871199842437,"d":"4.72"},{"v":0.467832756752086,"d":"0.47"},{"v":-1.09593521492149,"d":"-1.10"},{"v":0.0436957726828602,"d":"0.04"},{"v":0.50293482982961,"d":"0.50"},"down","yes"]
["ENSG00000141570","CBX8","ENST00000269385;ENST00000413392","GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0016569(covalent chromatin modification);GO:0000790(nuclear chromatin);GO:0050790(regulation of catalytic activity);GO:0005515(protein binding);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0031519(PcG protein complex);GO:0035102(PRC1 complex);GO:0035064(methylated histone binding);GO:0003727(single-stranded RNA binding);GO:0097027(ubiquitin-protein transferase activator activity);GO:0008284(positive regulation of cell proliferation);GO:0016574(histone ubiquitination);GO:0032967(positive regulation of collagen biosynthetic process);GO:0045739(positive regulation of DNA repair);GO:0070301(cellular response to hydrogen peroxide);GO:0000151(ubiquitin ligase complex);GO:0000792(heterochromatin);GO:0000792(heterochromatin)","NA","NA","NA","chromobox 8 [Source:HGNC Symbol;Acc:HGNC:15962]",{"v":0.283507440441883,"d":"0.28"},{"v":0.625648832132565,"d":"0.63"},{"v":0.453141484298036,"d":"0.45"},{"v":-1.14196652182149,"d":"-1.14"},{"v":0.0436976873588286,"d":"0.04"},{"v":0.50293482982961,"d":"0.50"},"down","yes"]
["ENSG00000148450","MSRB2","ENST00000376510;ENST00000468633;ENST00000472663","GO:0046872(metal ion binding);GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0003779(actin binding);GO:0005739(mitochondrion);GO:0006355(regulation of transcription, DNA-templated);GO:0006979(response to oxidative stress);GO:0016671(oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor);GO:0033743(peptide-methionine (R)-S-oxide reductase activity);GO:0030091(protein repair);GO:0005829(cytosol);GO:0030041(actin filament polymerization);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0008270(zinc ion binding);GO:0008270(zinc ion binding)","NA","NA","NA","methionine sulfoxide reductase B2 [Source:HGNC Symbol;Acc:HGNC:17061]",{"v":1.16238392251462,"d":"1.16"},{"v":2.50347299122807,"d":"2.50"},{"v":0.464308553192905,"d":"0.46"},{"v":-1.10684423733982,"d":"-1.11"},{"v":0.043849564604468,"d":"0.04"},{"v":0.504183162130383,"d":"0.50"},"down","yes"]
["MSTRG.3494","MBD6","ENST00000355673;MSTRG.3494.6;ENST00000548887;ENST00000552255;ENST00000549231;ENST00000546632;ENST00000546805;ENST00000552659;ENST00000551351;ENST00000549042;ENST00000548550","GO:0005634(nucleus);GO:0003677(DNA binding);GO:0005654(nucleoplasm);GO:0001650(fibrillar center);GO:0005694(chromosome);GO:0016579(protein deubiquitination);GO:0003682(chromatin binding);GO:0010369(chromocenter);GO:0010369(chromocenter)","NA","NA","NA","methyl-CpG binding domain protein 6 [Source:HGNC Symbol;Acc:HGNC:20445]",{"v":8.12899583421892,"d":"8.13"},{"v":2.65584408926674,"d":"2.66"},{"v":3.06079557420981,"d":"3.06"},{"v":1.6139066927178,"d":"1.61"},{"v":0.0439065365853989,"d":"0.04"},{"v":0.504225173591006,"d":"0.50"},"up","yes"]
["MSTRG.2867","SIK3","ENST00000445177;ENST00000465421;ENST00000446921;ENST00000485363;ENST00000413553;ENST00000480468;ENST00000454905;ENST00000480222;ENST00000488337;ENST00000415541;ENST00000472648;ENST00000375300;ENST00000497049","GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0006468(protein phosphorylation)","NA","NA","NA","SIK family kinase 3 [Source:HGNC Symbol;Acc:HGNC:29165]",{"v":7.14966048836996,"d":"7.15"},{"v":2.33676344148352,"d":"2.34"},{"v":3.05964239316878,"d":"3.06"},{"v":1.61336304254189,"d":"1.61"},{"v":0.0439481212379976,"d":"0.04"},{"v":0.504225173591006,"d":"0.50"},"up","yes"]
["MSTRG.1436","HIST3H2A","ENST00000366695","GO:0005634(nucleus);GO:0003677(DNA binding);GO:0046982(protein heterodimerization activity);GO:0000786(nucleosome);GO:0005694(chromosome);GO:0070062(extracellular exosome);GO:0006342(chromatin silencing);GO:0006337(nucleosome disassembly);GO:0000788(nuclear nucleosome);GO:0070914(UV-damage excision repair)","04217(Necroptosis);05322(Systemic lupus erythematosus);05034(Alcoholism)","K11251","NA","histone cluster 3 H2A [Source:HGNC Symbol;Acc:HGNC:20507]",{"v":4.439195,"d":"4.44"},{"v":9.451579,"d":"9.45"},{"v":0.469677606249707,"d":"0.47"},{"v":-1.09025728588326,"d":"-1.09"},{"v":0.0439834754884775,"d":"0.04"},{"v":0.504225173591006,"d":"0.50"},"down","yes"]
["MSTRG.5329","WDR61","ENST00000267973;ENST00000560946;ENST00000560807;ENST00000559848;ENST00000558311;ENST00000560610;ENST00000558459;ENST00000559700;ENST00000559940;ENST00000559332;ENST00000560063;ENST00000560569;ENST00000561347;ENST00000558412","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0005515(protein binding);GO:0016055(Wnt signaling pathway);GO:0016567(protein ubiquitination);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0006366(transcription from RNA polymerase II promoter);GO:0006368(transcription elongation from RNA polymerase II promoter);GO:0045638(negative regulation of myeloid cell differentiation);GO:0043928(exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay);GO:0080182(histone H3-K4 trimethylation);GO:0032968(positive regulation of transcription elongation from RNA polymerase II promoter);GO:0035327(transcriptionally active chromatin);GO:0051571(positive regulation of histone H3-K4 methylation);GO:0016593(Cdc73/Paf1 complex);GO:0055087(Ski complex);GO:2001162(positive regulation of histone H3-K79 methylation);GO:2001162(positive regulation of histone H3-K79 methylation)","03018(RNA degradation);03018(RNA degradation)","K12602","NA","WD repeat domain 61 [Source:HGNC Symbol;Acc:HGNC:30300]",{"v":1.26298143440033,"d":"1.26"},{"v":2.66807588267619,"d":"2.67"},{"v":0.473367883800032,"d":"0.47"},{"v":-1.0789662668338,"d":"-1.08"},{"v":0.044221054677255,"d":"0.04"},{"v":0.506362306682321,"d":"0.51"},"down","yes"]
["MSTRG.2603","POLD4;CLCF1;AP003419.2","ENST00000312419;ENST00000531239;ENST00000529704;ENST00000533429;ENST00000312438;ENST00000539074;ENST00000530584;ENST00000532830;ENST00000534515;ENST00000529000;ENST00000542982;ENST00000533438;ENST00000543494;ENST00000528087","GO:0005634(nucleus);GO:0005730(nucleolus);GO:0005829(cytosol);GO:0005739(mitochondrion);GO:0005515(protein binding);GO:0006281(DNA repair);GO:0006974(cellular response to DNA damage stimulus);GO:0006260(DNA replication);GO:0003887(DNA-directed DNA polymerase activity);GO:0000731(DNA synthesis involved in DNA repair);GO:0006261(DNA-dependent DNA replication);GO:0043625(delta DNA polymerase complex);GO:0005654(nucleoplasm);GO:0019985(translesion synthesis);GO:0006283(transcription-coupled nucleotide-excision repair);GO:0042769(DNA damage response, detection of DNA damage);GO:0006296(nucleotide-excision repair, DNA incision, 5'-to lesion);GO:0033683(nucleotide-excision repair, DNA incision);GO:0032201(telomere maintenance via semi-conservative replication);GO:0006297(nucleotide-excision repair, DNA gap filling);GO:0000723(telomere maintenance);GO:0006266(DNA ligation);GO:0006298(mismatch repair);GO:0008284(positive regulation of cell proliferation);GO:0042531(positive regulation of tyrosine phosphorylation of STAT protein);GO:0005622(intracellular);GO:0005576(extracellular region);GO:0005125(cytokine activity);GO:0005615(extracellular space);GO:0070062(extracellular exosome);GO:0007166(cell surface receptor signaling pathway);GO:0046982(protein heterodimerization activity);GO:0005102(receptor binding);GO:0019221(cytokine-mediated signaling pathway);GO:0043524(negative regulation of neuron apoptotic process);GO:0005127(ciliary neurotrophic factor receptor binding);GO:0097058(CRLF-CLCF1 complex);GO:0008083(growth factor activity);GO:0007259(JAK-STAT cascade);GO:0030890(positive regulation of B cell proliferation);GO:0030183(B cell differentiation);GO:0048711(positive regulation of astrocyte differentiation);GO:0097059(CNTFR-CLCF1 complex);GO:0002639(positive regulation of immunoglobulin production);GO:0048295(positive regulation of isotype switching to IgE isotypes);GO:0006298(mismatch repair)","00230(Purine metabolism);00240(Pyrimidine metabolism);03030(DNA replication);03410(Base excision repair);03420(Nucleotide excision repair);03430(Mismatch repair);03440(Homologous recombination);05166(HTLV-I infection);04060(Cytokine-cytokine receptor interaction);05166(HTLV-I infection)","K03505;K05421","NA","DNA polymerase delta 4, accessory subunit [Source:HGNC Symbol;Acc:HGNC:14106];cardiotrophin like cytokine factor 1 [Source:HGNC Symbol;Acc:HGNC:17412]",{"v":3.95211669725318,"d":"3.95"},{"v":8.31288276433121,"d":"8.31"},{"v":0.475420718575614,"d":"0.48"},{"v":-1.072723318374,"d":"-1.07"},{"v":0.0442571033568032,"d":"0.04"},{"v":0.506362306682321,"d":"0.51"},"down","yes"]
["MSTRG.9627","APMAP","ENST00000217456;ENST00000451442","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0009058(biosynthetic process);GO:0016844(strictosidine synthase activity);GO:0005783(endoplasmic reticulum);GO:0008150(biological_process);GO:0070062(extracellular exosome);GO:0009986(cell surface);GO:0004064(arylesterase activity);GO:0004064(arylesterase activity)","NA","NA","NA","adipocyte plasma membrane associated protein [Source:HGNC Symbol;Acc:HGNC:13238]",{"v":29.938820797881,"d":"29.94"},{"v":62.7684746487367,"d":"62.77"},{"v":0.476972253434926,"d":"0.48"},{"v":-1.06802275108032,"d":"-1.07"},{"v":0.04431029270024,"d":"0.04"},{"v":0.506396265795906,"d":"0.51"},"down","yes"]
["ENSG00000108557","RAI1","ENST00000353383;ENST00000489697;ENST00000471135;ENST00000583166;ENST00000582514","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0005654(nucleoplasm);GO:0005739(mitochondrion);GO:0005515(protein binding);GO:0048511(rhythmic process);GO:0045893(positive regulation of transcription, DNA-templated);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0032922(circadian regulation of gene expression);GO:0035326(enhancer binding);GO:0001501(skeletal system development);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0040015(negative regulation of multicellular organism growth);GO:0040015(negative regulation of multicellular organism growth)","NA","NA","NA","retinoic acid induced 1 [Source:HGNC Symbol;Acc:HGNC:9834]",{"v":1.37276288063551,"d":"1.37"},{"v":0.446837753636645,"d":"0.45"},{"v":3.07217299671549,"d":"3.07"},{"v":1.61925945775058,"d":"1.62"},{"v":0.0443472834163813,"d":"0.04"},{"v":0.506396265795906,"d":"0.51"},"up","yes"]
["MSTRG.9758","ADA","ENST00000492931;ENST00000372874;ENST00000537820;ENST00000536532;ENST00000539235;ENST00000535573;ENST00000464097;ENST00000545776","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0046872(metal ion binding);GO:0016787(hydrolase activity);GO:0007155(cell adhesion);GO:0008270(zinc ion binding);GO:0019239(deaminase activity);GO:0009168(purine ribonucleoside monophosphate biosynthetic process);GO:0005886(plasma membrane);GO:0030054(cell junction);GO:0031410(cytoplasmic vesicle);GO:0009117(nucleotide metabolic process);GO:0005764(lysosome);GO:0004000(adenosine deaminase activity);GO:0005515(protein binding);GO:0001883(purine nucleoside binding);GO:0001666(response to hypoxia);GO:0001701(in utero embryonic development);GO:0001821(histamine secretion);GO:0001829(trophectodermal cell differentiation);GO:0001889(liver development);GO:0001890(placenta development);GO:0002314(germinal center B cell differentiation);GO:0002636(positive regulation of germinal center formation);GO:0002686(negative regulation of leukocyte migration);GO:0002906(negative regulation of mature B cell apoptotic process);GO:0006154(adenosine catabolic process);GO:0006157(deoxyadenosine catabolic process);GO:0007568(aging);GO:0010460(positive regulation of heart rate);GO:0030324(lung development);GO:0030890(positive regulation of B cell proliferation);GO:0033089(positive regulation of T cell differentiation in thymus);GO:0033197(response to vitamin E);GO:0042323(negative regulation of circadian sleep/wake cycle, non-REM sleep);GO:0042493(response to drug);GO:0042542(response to hydrogen peroxide);GO:0043066(negative regulation of apoptotic process);GO:0043278(response to morphine);GO:0045187(regulation of circadian sleep/wake cycle, sleep);GO:0045580(regulation of T cell differentiation);GO:0045582(positive regulation of T cell differentiation);GO:0045987(positive regulation of smooth muscle contraction);GO:0046061(dATP catabolic process);GO:0046085(adenosine metabolic process);GO:0046101(hypoxanthine biosynthetic process);GO:0046103(inosine biosynthetic process);GO:0046111(xanthine biosynthetic process);GO:0046638(positive regulation of alpha-beta T cell differentiation);GO:0048286(lung alveolus development);GO:0048541(Peyer's patch development);GO:0048566(embryonic digestive tract development);GO:0050728(negative regulation of inflammatory response);GO:0050850(positive regulation of calcium-mediated signaling);GO:0050862(positive regulation of T cell receptor signaling pathway);GO:0050870(positive regulation of T cell activation);GO:0060407(negative regulation of penile erection);GO:0070244(negative regulation of thymocyte apoptotic process);GO:0070256(negative regulation of mucus secretion);GO:0005615(extracellular space);GO:0032839(dendrite cytoplasm);GO:0043025(neuronal cell body);GO:0005829(cytosol);GO:0009986(cell surface);GO:0042110(T cell activation);GO:0060205(cytoplasmic vesicle lumen);GO:0009897(external side of plasma membrane);GO:0043101(purine-containing compound salvage);GO:0032261(purine nucleotide salvage);GO:0033632(regulation of cell-cell adhesion mediated by integrin);GO:0043103(hypoxanthine salvage);GO:0060169(negative regulation of adenosine receptor signaling pathway);GO:0060169(negative regulation of adenosine receptor signaling pathway)","00230(Purine metabolism);05340(Primary immunodeficiency);05340(Primary immunodeficiency)","K01488","EC:3.5.4.4","adenosine deaminase [Source:HGNC Symbol;Acc:HGNC:186]",{"v":2.98325111290323,"d":"2.98"},{"v":6.29625463779804,"d":"6.30"},{"v":0.473813605789385,"d":"0.47"},{"v":-1.07760846802082,"d":"-1.08"},{"v":0.0444647578345286,"d":"0.04"},{"v":0.506930771689793,"d":"0.51"},"down","yes"]
["MSTRG.13974","AC008038.1;CHCHD3","ENST00000634247;ENST00000262570;ENST00000423635;ENST00000496427;ENST00000481152","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0005743(mitochondrial inner membrane);GO:0005739(mitochondrion);GO:0005515(protein binding);GO:0061617(MICOS complex);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0070062(extracellular exosome);GO:0032947(protein complex scaffold);GO:0019902(phosphatase binding);GO:0007007(inner mitochondrial membrane organization);GO:0008053(mitochondrial fusion);GO:0042407(cristae formation);GO:0001227(transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding);GO:0016021(integral component of membrane);GO:0016021(integral component of membrane)","NA","NA","NA","coiled-coil-helix-coiled-coil-helix domain containing 3 [Source:HGNC Symbol;Acc:HGNC:21906]",{"v":19.8321597680525,"d":"19.83"},{"v":6.50937946126915,"d":"6.51"},{"v":3.04670512543538,"d":"3.05"},{"v":1.60724987591603,"d":"1.61"},{"v":0.0445184007970487,"d":"0.04"},{"v":0.506930771689793,"d":"0.51"},"up","yes"]
["MSTRG.13126","EEF1A1","ENST00000610520;ENST00000490569;ENST00000495333;ENST00000331523;ENST00000309268;ENST00000615060;ENST00000491404;ENST00000455918;ENST00000316292;ENST00000488500;ENST00000356303","GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0006412(translation);GO:0005525(GTP binding);GO:0000166(nucleotide binding);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003924(GTPase activity);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0005615(extracellular space);GO:0003746(translation elongation factor activity);GO:0006414(translational elongation);GO:0000049(tRNA binding);GO:0005730(nucleolus);GO:0005576(extracellular region);GO:0070062(extracellular exosome);GO:0019901(protein kinase binding);GO:0032587(ruffle membrane);GO:0043312(neutrophil degranulation);GO:0034774(secretory granule lumen);GO:1904813(ficolin-1-rich granule lumen);GO:0030864(cortical actin cytoskeleton);GO:0071364(cellular response to epidermal growth factor stimulus);GO:0006479(protein methylation);GO:1904714(regulation of chaperone-mediated autophagy);GO:0005853(eukaryotic translation elongation factor 1 complex);GO:0043209(myelin sheath);GO:0098574(cytoplasmic side of lysosomal membrane);GO:0098574(cytoplasmic side of lysosomal membrane)","03013(RNA transport);05134(Legionellosis);05134(Legionellosis)","K03231","NA","eukaryotic translation elongation factor 1 alpha 1 [Source:HGNC Symbol;Acc:HGNC:3189]",{"v":844.689546175185,"d":"844.69"},{"v":1767.50729320158,"d":"1767.51"},{"v":0.477898761393597,"d":"0.48"},{"v":-1.06522306644011,"d":"-1.07"},{"v":0.0445988931818742,"d":"0.04"},{"v":0.506930771689793,"d":"0.51"},"down","yes"]
["ENSG00000181035","SLC25A42","ENST00000318596;ENST00000600251;ENST00000596819;ENST00000594070","GO:0006810(transport);GO:0005634(nucleus);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0055085(transmembrane transport);GO:0005739(mitochondrion);GO:0005743(mitochondrial inner membrane);GO:0006839(mitochondrial transport);GO:0015217(ADP transmembrane transporter activity);GO:0015228(coenzyme A transmembrane transporter activity);GO:0080122(AMP transmembrane transporter activity);GO:0015866(ADP transport);GO:0005347(ATP transmembrane transporter activity);GO:0015867(ATP transport);GO:0043262(adenosine-diphosphatase activity);GO:0035349(coenzyme A transmembrane transport);GO:0080121(AMP transport);GO:0080121(AMP transport)","NA","NA","NA","solute carrier family 25 member 42 [Source:HGNC Symbol;Acc:HGNC:28380]",{"v":3.21486796658553,"d":"3.21"},{"v":1.04366088625802,"d":"1.04"},{"v":3.08037601956344,"d":"3.08"},{"v":1.62310647054612,"d":"1.62"},{"v":0.0446424415113276,"d":"0.04"},{"v":0.506930771689793,"d":"0.51"},"up","yes"]
["MSTRG.8018","GATAD2A","MSTRG.8018.3;MSTRG.8018.6;ENST00000360315;ENST00000417582;ENST00000429242;ENST00000358713;ENST00000609040;ENST00000448576;ENST00000473184;ENST00000444839;ENST00000418032;ENST00000494516;ENST00000457895;ENST00000432704;ENST00000404158","GO:0005654(nucleoplasm);GO:0005634(nucleus);GO:0016607(nuclear speck);GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0043565(sequence-specific DNA binding);GO:0005515(protein binding);GO:0030674(protein binding, bridging);GO:0045892(negative regulation of transcription, DNA-templated);GO:0016581(NuRD complex);GO:0006306(DNA methylation);GO:0006306(DNA methylation)","NA","NA","NA","GATA zinc finger domain containing 2A [Source:HGNC Symbol;Acc:HGNC:29989]",{"v":11.1012434958202,"d":"11.10"},{"v":3.64279227984103,"d":"3.64"},{"v":3.04745443687628,"d":"3.05"},{"v":1.60760465097378,"d":"1.61"},{"v":0.0446831428961472,"d":"0.04"},{"v":0.506930771689793,"d":"0.51"},"up","yes"]
["MSTRG.7843","ASNA1","ENST00000357332;ENST00000611688;ENST00000590633;ENST00000586561","GO:0006810(transport);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0005730(nucleolus);GO:0016787(hydrolase activity);GO:0005783(endoplasmic reticulum);GO:0005515(protein binding);GO:0016887(ATPase activity);GO:0015698(inorganic anion transport);GO:0005789(endoplasmic reticulum membrane);GO:0070062(extracellular exosome);GO:0005215(transporter activity);GO:0036498(IRE1-mediated unfolded protein response);GO:0015105(arsenite transmembrane transporter activity);GO:0043492(ATPase activity, coupled to movement of substances);GO:0045048(protein insertion into ER membrane);GO:0045048(protein insertion into ER membrane)","NA","NA","NA","arsA arsenite transporter, ATP-binding, homolog 1 (bacterial) [Source:HGNC Symbol;Acc:HGNC:752]",{"v":14.4688084164649,"d":"14.47"},{"v":30.3401441355932,"d":"30.34"},{"v":0.476886607782821,"d":"0.48"},{"v":-1.06828182621799,"d":"-1.07"},{"v":0.044703677353775,"d":"0.04"},{"v":0.506930771689793,"d":"0.51"},"down","yes"]
["ENSG00000197782","ZNF780A","ENST00000340963;ENST00000601715;ENST00000450241;ENST00000595687;ENST00000601688;ENST00000414720;ENST00000599368;ENST00000455521;ENST00000594395;ENST00000599972;ENST00000595773","GO:0003676(nucleic acid binding);GO:0046872(metal ion binding);GO:0006355(regulation of transcription, DNA-templated);GO:0005622(intracellular);GO:0005634(nucleus);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding)","NA","NA","NA","zinc finger protein 780A [Source:HGNC Symbol;Acc:HGNC:27603]",{"v":0.39340927207727,"d":"0.39"},{"v":0.123326648896136,"d":"0.12"},{"v":3.18997779959621,"d":"3.19"},{"v":1.67354638370052,"d":"1.67"},{"v":0.0447203343483204,"d":"0.04"},{"v":0.506930771689793,"d":"0.51"},"up","yes"]
["MSTRG.2099","POLR2L","ENST00000322028;ENST00000534030","GO:0005634(nucleus);GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0003677(DNA binding);GO:0006351(transcription, DNA-templated);GO:0005515(protein binding);GO:0003899(DNA-directed 5'-3' RNA polymerase activity);GO:0005666(DNA-directed RNA polymerase III complex);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0006366(transcription from RNA polymerase II promoter);GO:0045815(positive regulation of gene expression, epigenetic);GO:0006368(transcription elongation from RNA polymerase II promoter);GO:0006370(7-methylguanosine mRNA capping);GO:0050434(positive regulation of viral transcription);GO:0006367(transcription initiation from RNA polymerase II promoter);GO:0042795(snRNA transcription from RNA polymerase II promoter);GO:0001056(RNA polymerase III activity);GO:0006383(transcription from RNA polymerase III promoter);GO:0032481(positive regulation of type I interferon production);GO:0000398(mRNA splicing, via spliceosome);GO:0001054(RNA polymerase I activity);GO:0006361(transcription initiation from RNA polymerase I promoter);GO:0006362(transcription elongation from RNA polymerase I promoter);GO:0006363(termination of RNA polymerase I transcription);GO:0005736(DNA-directed RNA polymerase I complex);GO:0060964(regulation of gene silencing by miRNA);GO:0006283(transcription-coupled nucleotide-excision repair);GO:0008543(fibroblast growth factor receptor signaling pathway);GO:0016070(RNA metabolic process);GO:0035019(somatic stem cell population maintenance);GO:0005665(DNA-directed RNA polymerase II, core complex);GO:0006356(regulation of transcription from RNA polymerase I promoter);GO:0001055(RNA polymerase II activity);GO:0001055(RNA polymerase II activity)","00230(Purine metabolism);00240(Pyrimidine metabolism);03020(RNA polymerase);04623(Cytosolic DNA-sensing pathway);05016(Huntington's disease);05169(Epstein-Barr virus infection);05169(Epstein-Barr virus infection)","K03007","NA","RNA polymerase II subunit L [Source:HGNC Symbol;Acc:HGNC:9199]",{"v":5.90413394045534,"d":"5.90"},{"v":12.4428805779334,"d":"12.44"},{"v":0.474498963762934,"d":"0.47"},{"v":-1.07552315827471,"d":"-1.08"},{"v":0.0447433084458829,"d":"0.04"},{"v":0.506930771689793,"d":"0.51"},"down","yes"]
["ENSG00000133216","EPHB2","ENST00000374632;ENST00000374627;ENST00000400191;ENST00000374630","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0005634(nucleus);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0004713(protein tyrosine kinase activity);GO:0005003(ephrin receptor activity);GO:0007169(transmembrane receptor protein tyrosine kinase signaling pathway);GO:0005887(integral component of plasma membrane);GO:0005886(plasma membrane);GO:0042995(cell projection);GO:0005515(protein binding);GO:0004714(transmembrane receptor protein tyrosine kinase activity);GO:0007275(multicellular organism development);GO:0007399(nervous system development);GO:0030425(dendrite);GO:0005576(extracellular region);GO:0030424(axon);GO:0005829(cytosol);GO:0010628(positive regulation of gene expression);GO:0048013(ephrin receptor signaling pathway);GO:0060997(dendritic spine morphogenesis);GO:0060021(palate development);GO:0001525(angiogenesis);GO:0007411(axon guidance);GO:0071679(commissural neuron axon guidance);GO:0051965(positive regulation of synapse assembly);GO:0042472(inner ear morphogenesis);GO:0007612(learning);GO:0007611(learning or memory);GO:0018108(peptidyl-tyrosine phosphorylation);GO:0098794(postsynapse);GO:1900273(positive regulation of long-term synaptic potentiation);GO:0001540(amyloid-beta binding);GO:0005005(transmembrane-ephrin receptor activity);GO:0044877(macromolecular complex binding);GO:0001655(urogenital system development);GO:0001933(negative regulation of protein phosphorylation);GO:0007413(axonal fasciculation);GO:0022038(corpus callosum development);GO:0031915(positive regulation of synaptic plasticity);GO:0046580(negative regulation of Ras protein signal transduction);GO:0048168(regulation of neuronal synaptic plasticity);GO:0050878(regulation of body fluid levels);GO:0051389(inactivation of MAPKK activity);GO:0060996(dendritic spine development);GO:0070373(negative regulation of ERK1 and ERK2 cascade);GO:1903078(positive regulation of protein localization to plasma membrane);GO:1904782(negative regulation of NMDA glutamate receptor activity);GO:1904783(positive regulation of NMDA glutamate receptor activity);GO:0004872(receptor activity);GO:0005102(receptor binding);GO:0008046(axon guidance receptor activity);GO:0042802(identical protein binding);GO:0000902(cell morphogenesis);GO:0009887(animal organ morphogenesis);GO:0021631(optic nerve morphogenesis);GO:0021952(central nervous system projection neuron axonogenesis);GO:0031290(retinal ganglion cell axon guidance);GO:0048170(positive regulation of long-term neuronal synaptic plasticity);GO:0048593(camera-type eye morphogenesis);GO:0050770(regulation of axonogenesis);GO:0050771(negative regulation of axonogenesis);GO:0099557(trans-synaptic signaling by trans-synaptic complex, modulating synaptic transmission);GO:0106028(-);GO:0043025(neuronal cell body);GO:0043025(neuronal cell body)","04360(Axon guidance);04360(Axon guidance)","K05111","EC:2.7.10.1","EPH receptor B2 [Source:HGNC Symbol;Acc:HGNC:3393]",{"v":0.264335861057846,"d":"0.26"},{"v":0.08271730105465,"d":"0.08"},{"v":3.19565384372495,"d":"3.20"},{"v":1.67611114262508,"d":"1.68"},{"v":0.0448019466982888,"d":"0.04"},{"v":0.507033173476982,"d":"0.51"},"up","yes"]
["ENSG00000135679","MDM2","ENST00000258149;ENST00000311420;ENST00000493419;ENST00000258148;ENST00000537182;ENST00000428863;ENST00000543046;ENST00000517852;ENST00000393415;ENST00000400501;ENST00000393417;ENST00000393412;ENST00000542502;ENST00000539479;ENST00000393416;ENST00000544125","GO:0008284(positive regulation of cell proliferation);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0043066(negative regulation of apoptotic process);GO:0016740(transferase activity);GO:0016567(protein ubiquitination);GO:0008270(zinc ion binding);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0016874(ligase activity);GO:0005515(protein binding);GO:0071157(negative regulation of cell cycle arrest);GO:0005654(nucleoplasm);GO:0016925(protein sumoylation);GO:0005730(nucleolus);GO:0005886(plasma membrane);GO:0042802(identical protein binding);GO:0061630(ubiquitin protein ligase activity);GO:0006977(DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest);GO:0005829(cytosol);GO:0016579(protein deubiquitination);GO:0016032(viral process);GO:0042787(protein ubiquitination involved in ubiquitin-dependent protein catabolic process);GO:0031625(ubiquitin protein ligase binding);GO:0043021(ribonucleoprotein complex binding);GO:0019899(enzyme binding);GO:0004842(ubiquitin-protein transferase activity);GO:0045892(negative regulation of transcription, DNA-templated);GO:0019789(SUMO transferase activity);GO:1901796(regulation of signal transduction by p53 class mediator);GO:0043234(protein complex);GO:0030666(endocytic vesicle membrane);GO:0032436(positive regulation of proteasomal ubiquitin-dependent protein catabolic process);GO:0034504(protein localization to nucleus);GO:0006461(protein complex assembly);GO:0071456(cellular response to hypoxia);GO:0002039(p53 binding);GO:0043518(negative regulation of DNA damage response, signal transduction by p53 class mediator);GO:0046677(response to antibiotic);GO:0051865(protein autoubiquitination);GO:0045931(positive regulation of mitotic cell cycle);GO:0097718(disordered domain specific binding);GO:0042176(regulation of protein catabolic process);GO:0071480(cellular response to gamma radiation);GO:0047485(protein N-terminus binding);GO:0031648(protein destabilization);GO:0016604(nuclear body);GO:0072717(cellular response to actinomycin D);GO:1990000(amyloid fibril formation);GO:0045184(establishment of protein localization);GO:0036369(transcription factor catabolic process);GO:0008097(5S rRNA binding);GO:0042975(peroxisome proliferator activated receptor binding);GO:0061663(NEDD8 ligase activity);GO:0097110(scaffold protein binding);GO:0001568(blood vessel development);GO:0001974(blood vessel remodeling);GO:0002027(regulation of heart rate);GO:0003170(heart valve development);GO:0003181(atrioventricular valve morphogenesis);GO:0003203(endocardial cushion morphogenesis);GO:0003281(ventricular septum development);GO:0003283(atrial septum development);GO:0007089(traversing start control point of mitotic cell cycle);GO:0007507(heart development);GO:0009636(response to toxic substance);GO:0010039(response to iron ion);GO:0010468(regulation of gene expression);GO:0010628(positive regulation of gene expression);GO:0010629(negative regulation of gene expression);GO:0010955(negative regulation of protein processing);GO:0010977(negative regulation of neuron projection development);GO:0018205(peptidyl-lysine modification);GO:0032026(response to magnesium ion);GO:0042220(response to cocaine);GO:0042493(response to drug);GO:0043154(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process);GO:0043278(response to morphine);GO:0045472(response to ether);GO:0045787(positive regulation of cell cycle);GO:0046827(positive regulation of protein export from nucleus);GO:0048545(response to steroid hormone);GO:0051603(proteolysis involved in cellular protein catabolic process);GO:0060411(cardiac septum morphogenesis);GO:0070301(cellular response to hydrogen peroxide);GO:0071236(cellular response to antibiotic);GO:0071301(cellular response to vitamin B1);GO:0071310(cellular response to organic substance);GO:0071312(cellular response to alkaloid);GO:0071363(cellular response to growth factor stimulus);GO:0071375(cellular response to peptide hormone stimulus);GO:0071391(cellular response to estrogen stimulus);GO:0071407(cellular response to organic cyclic compound);GO:0071494(cellular response to UV-C);GO:1901797(negative regulation of signal transduction by p53 class mediator);GO:1902254(negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator);GO:1904404(response to formaldehyde);GO:1904707(positive regulation of vascular smooth muscle cell proliferation);GO:1904754(positive regulation of vascular associated smooth muscle cell migration);GO:1990785(response to water-immersion restraint stress);GO:0045202(synapse);GO:0045202(synapse)","04120(Ubiquitin mediated proteolysis);04068(FoxO signaling pathway);04151(PI3K-Akt signaling pathway);04144(Endocytosis);04110(Cell cycle);04115(p53 signaling pathway);04218(Cellular senescence);04919(Thyroid hormone signaling pathway);05200(Pathways in cancer);05202(Transcriptional misregulation in cancers);05206(MicroRNAs in cancer);05205(Proteoglycans in cancer);05203(Viral carcinogenesis);05214(Glioma);05220(Chronic myeloid leukemia);05218(Melanoma);05219(Bladder cancer);05215(Prostate cancer);05169(Epstein-Barr virus infection);05165(Human papillomavirus infection);01524(Platinum drug resistance);01522(Endocrine resistance);01522(Endocrine resistance)","K06643","EC:2.3.2.27","MDM2 proto-oncogene [Source:HGNC Symbol;Acc:HGNC:6973]",{"v":4.32786804182681,"d":"4.33"},{"v":1.42074773532293,"d":"1.42"},{"v":3.04619035049393,"d":"3.05"},{"v":1.60700609584138,"d":"1.61"},{"v":0.0448662313859203,"d":"0.04"},{"v":0.507033173476982,"d":"0.51"},"up","yes"]
["MSTRG.2557","RELA","ENST00000525693;ENST00000406246;ENST00000612991;ENST00000525858;ENST00000532776;ENST00000308639;ENST00000531484;ENST00000526257;ENST00000529389;ENST00000533187;ENST00000533546;ENST00000534558;ENST00000527749;ENST00000526738;ENST00000527874;ENST00000531238;ENST00000526283;ENST00000527909;ENST00000534283;ENST00000534305;ENST00000527074;ENST00000529330","GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0006355(regulation of transcription, DNA-templated);GO:0006366(transcription from RNA polymerase II promoter);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0031490(chromatin DNA binding);GO:0042803(protein homodimerization activity);GO:0005515(protein binding);GO:0051092(positive regulation of NF-kappaB transcription factor activity);GO:0045893(positive regulation of transcription, DNA-templated);GO:0006954(inflammatory response);GO:0038095(Fc-epsilon receptor signaling pathway);GO:0042802(identical protein binding);GO:0071159(NF-kappaB complex);GO:0051607(defense response to virus);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:0001078(transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0005654(nucleoplasm);GO:0019901(protein kinase binding);GO:0002223(stimulatory C-type lectin receptor signaling pathway);GO:0050852(T cell receptor signaling pathway);GO:0003682(chromatin binding);GO:0071347(cellular response to interleukin-1);GO:0071356(cellular response to tumor necrosis factor);GO:0016032(viral process);GO:0031625(ubiquitin protein ligase binding);GO:0043123(positive regulation of I-kappaB kinase/NF-kappaB signaling);GO:0008284(positive regulation of cell proliferation);GO:0047485(protein N-terminus binding);GO:0043066(negative regulation of apoptotic process);GO:0008134(transcription factor binding);GO:0044212(transcription regulatory region DNA binding);GO:0045892(negative regulation of transcription, DNA-templated);GO:0000790(nuclear chromatin);GO:0046982(protein heterodimerization activity);GO:0010033(response to organic substance);GO:0001077(transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0000977(RNA polymerase II regulatory region sequence-specific DNA binding);GO:1902895(positive regulation of pri-miRNA transcription from RNA polymerase II promoter);GO:0032481(positive regulation of type I interferon production);GO:0019221(cytokine-mediated signaling pathway);GO:0042826(histone deacetylase binding);GO:0051059(NF-kappaB binding);GO:0070555(response to interleukin-1);GO:0043620(regulation of DNA-templated transcription in response to stress);GO:1901223(negative regulation of NIK/NF-kappaB signaling);GO:0005667(transcription factor complex);GO:0071223(cellular response to lipoteichoic acid);GO:0000983(transcription factor activity, RNA polymerase II core promoter sequence-specific);GO:0006968(cellular defense response);GO:0050727(regulation of inflammatory response);GO:1901224(positive regulation of NIK/NF-kappaB signaling);GO:0070301(cellular response to hydrogen peroxide);GO:0042301(phosphate ion binding);GO:0003705(transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding);GO:2000630(positive regulation of miRNA metabolic process);GO:2001237(negative regulation of extrinsic apoptotic signaling pathway);GO:0010224(response to UV-B);GO:0031293(membrane protein intracellular domain proteolysis);GO:0000980(RNA polymerase II distal enhancer sequence-specific DNA binding);GO:0001205(transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding);GO:0071375(cellular response to peptide hormone stimulus);GO:0042805(actinin binding);GO:0071316(cellular response to nicotine);GO:0071354(cellular response to interleukin-6);GO:0070491(repressing transcription factor binding);GO:0050862(positive regulation of T cell receptor signaling pathway);GO:0033209(tumor necrosis factor-mediated signaling pathway);GO:0033613(activating transcription factor binding);GO:1901222(regulation of NIK/NF-kappaB signaling);GO:0033256(I-kappaB/NF-kappaB complex);GO:0001046(core promoter sequence-specific DNA binding);GO:0019899(enzyme binding);GO:0032403(protein complex binding);GO:0043565(sequence-specific DNA binding);GO:0071532(ankyrin repeat binding);GO:0001889(liver development);GO:0001942(hair follicle development);GO:0006117(acetaldehyde metabolic process);GO:0006952(defense response);GO:0007568(aging);GO:0009612(response to mechanical stimulus);GO:0009617(response to bacterium);GO:0009887(animal organ morphogenesis);GO:0010035(response to inorganic substance);GO:0014040(positive regulation of Schwann cell differentiation);GO:0014070(response to organic cyclic compound);GO:0032332(positive regulation of chondrocyte differentiation);GO:0032495(response to muramyl dipeptide);GO:0032496(response to lipopolysaccharide);GO:0032570(response to progesterone);GO:0032868(response to insulin);GO:0033234(negative regulation of protein sumoylation);GO:0033590(response to cobalamin);GO:0034097(response to cytokine);GO:0035729(cellular response to hepatocyte growth factor stimulus);GO:0035994(response to muscle stretch);GO:0042177(negative regulation of protein catabolic process);GO:0042493(response to drug);GO:0042542(response to hydrogen peroxide);GO:0043200(response to amino acid);GO:0043278(response to morphine);GO:0045084(positive regulation of interleukin-12 biosynthetic process);GO:0046627(negative regulation of insulin receptor signaling pathway);GO:0051591(response to cAMP);GO:0070431(nucleotide-binding oligomerization domain containing 2 signaling pathway);GO:0071222(cellular response to lipopolysaccharide);GO:0071224(cellular response to peptidoglycan);GO:1901522(positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus);GO:0035525(NF-kappaB p50/p65 complex);GO:0043234(protein complex);GO:0043234(protein complex)","04014(Ras signaling pathway);04010(MAPK signaling pathway);04064(NF-kappa B signaling pathway);04668(TNF signaling pathway);04066(HIF-1 signaling pathway);04071(Sphingolipid signaling pathway);04024(cAMP signaling pathway);04151(PI3K-Akt signaling pathway);04137(Mitophagy - animal);04210(Apoptosis);04218(Cellular senescence);04620(Toll-like receptor signaling pathway);04621(NOD-like receptor signaling pathway);04622(RIG-I-like receptor signaling pathway);04623(Cytosolic DNA-sensing pathway);04660(T cell receptor signaling pathway);04658(Th1 and Th2 cell differentiation);04659(Th17 cell differentiation);04657(IL-17 signaling pathway);04662(B cell receptor signaling pathway);04062(Chemokine signaling pathway);04920(Adipocytokine signaling pathway);04917(Prolactin signaling pathway);04926(Relaxin signaling pathway);04722(Neurotrophin signaling pathway);04380(Osteoclast differentiation);04211(Longevity regulating pathway - mammal);05200(Pathways in cancer);05202(Transcriptional misregulation in cancers);05203(Viral carcinogenesis);05212(Pancreatic cancer);05221(Acute myeloid leukemia);05220(Chronic myeloid leukemia);05215(Prostate cancer);05222(Small cell lung cancer);05321(Inflammatiory bowel disease (IBD));05030(Cocaine addiction);05418(Fluid shear stress and atherosclerosis);04932(Non-alcoholic fatty liver disease (NAFLD));04931(Insulin resistance);04933(AGE-RAGE signaling pathway in diabetic complications);05120(Epithelial cell signaling in Helicobacter pylori infection);05132(Salmonella infection);05131(Shigellosis);05133(Pertussis);05134(Legionellosis);05152(Tuberculosis);05166(HTLV-I infection);05162(Measles);05164(Influenza A);05161(Hepatitis B);05160(Hepatitis C);05168(Herpes simplex infection);05167(Kaposi's sarcoma-associated herpesvirus infection);05169(Epstein-Barr virus infection);05165(Human papillomavirus infection);05146(Amoebiasis);05145(Toxoplasmosis);05140(Leishmaniasis);05142(Chagas disease (American trypanosomiasis));01523(Antifolate resistance);01523(Antifolate resistance)","K04735","NA","RELA proto-oncogene, NF-kB subunit [Source:HGNC Symbol;Acc:HGNC:9955]",{"v":11.7016595867496,"d":"11.70"},{"v":3.8402719295388,"d":"3.84"},{"v":3.04709140432014,"d":"3.05"},{"v":1.6074327775372,"d":"1.61"},{"v":0.0448833292288244,"d":"0.04"},{"v":0.507033173476982,"d":"0.51"},"up","yes"]
["MSTRG.7099","ICAM2","ENST00000579687;ENST00000579788;ENST00000418105;ENST00000449662;ENST00000584084;ENST00000583366;ENST00000578892;ENST00000581417;ENST00000580011;ENST00000580389;ENST00000583186;ENST00000578379;ENST00000412356;ENST00000578313;ENST00000584403","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016337(single organismal cell-cell adhesion);GO:0007155(cell adhesion);GO:0050776(regulation of immune response);GO:0005886(plasma membrane);GO:0005887(integral component of plasma membrane);GO:0070062(extracellular exosome);GO:0002223(stimulatory C-type lectin receptor signaling pathway);GO:0030198(extracellular matrix organization);GO:0005178(integrin binding);GO:0032154(cleavage furrow);GO:0001931(uropod);GO:0071944(cell periphery);GO:0071944(cell periphery)","04514(Cell adhesion molecules (CAMs));04650(Natural killer cell mediated cytotoxicity);04650(Natural killer cell mediated cytotoxicity)","K06523","NA","intercellular adhesion molecule 2 [Source:HGNC Symbol;Acc:HGNC:5345]",{"v":6.62121627104533,"d":"6.62"},{"v":13.9221138282455,"d":"13.92"},{"v":0.475589867510784,"d":"0.48"},{"v":-1.07221011623706,"d":"-1.07"},{"v":0.0450029531191825,"d":"0.05"},{"v":0.507890470916488,"d":"0.51"},"down","yes"]
["MSTRG.2664","NUMA1","MSTRG.2664.2;MSTRG.2664.1;ENST00000545721;ENST00000543009;ENST00000546036;ENST00000544129;ENST00000613205;ENST00000537930;ENST00000537905;ENST00000534987;ENST00000536119;ENST00000544238;ENST00000540843;ENST00000540588;ENST00000541262;ENST00000543450;ENST00000541641;ENST00000368959;ENST00000535838;ENST00000358965;ENST00000351960;ENST00000535087;ENST00000620566;ENST00000541584;ENST00000542977;ENST00000543937;ENST00000616538;ENST00000534971;ENST00000535111;ENST00000540626;MSTRG.2664.3;ENST00000393695","GO:0005654(nucleoplasm);GO:0000139(Golgi membrane);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005829(cytosol);GO:0051301(cell division);GO:0005694(chromosome);GO:0005886(plasma membrane);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0007049(cell cycle);GO:0005874(microtubule);GO:0008017(microtubule binding);GO:0000922(spindle pole);GO:0005813(centrosome);GO:0005815(microtubule organizing center);GO:0007059(chromosome segregation);GO:0008289(lipid binding);GO:0035091(phosphatidylinositol binding);GO:0070062(extracellular exosome);GO:0005938(cell cortex);GO:0070840(dynein complex binding);GO:0043234(protein complex);GO:0005876(spindle microtubule);GO:0019904(protein domain specific binding);GO:0016363(nuclear matrix);GO:0097431(mitotic spindle pole);GO:1990023(mitotic spindle midzone);GO:0015631(tubulin binding);GO:0005198(structural molecule activity);GO:0000132(establishment of mitotic spindle orientation);GO:0099738(cell cortex region);GO:0005819(spindle);GO:0006997(nucleus organization);GO:1904778(positive regulation of protein localization to cell cortex);GO:0001578(microtubule bundle formation);GO:0072686(mitotic spindle);GO:0051010(microtubule plus-end binding);GO:0045618(positive regulation of keratinocyte differentiation);GO:0097718(disordered domain specific binding);GO:0097427(microtubule bundle);GO:0036449(microtubule minus-end);GO:0008022(protein C-terminus binding);GO:0031616(spindle pole centrosome);GO:0031116(positive regulation of microtubule polymerization);GO:0030513(positive regulation of BMP signaling pathway);GO:0019897(extrinsic component of plasma membrane);GO:0030953(astral microtubule organization);GO:0035371(microtubule plus-end);GO:0060236(regulation of mitotic spindle organization);GO:1905832(positive regulation of spindle assembly);GO:0051011(microtubule minus-end binding);GO:0032388(positive regulation of intracellular transport);GO:0090235(regulation of metaphase plate congression);GO:0051798(positive regulation of hair follicle development);GO:0051984(positive regulation of chromosome segregation);GO:0055048(anastral spindle assembly);GO:1902365(positive regulation of protein localization to spindle pole body);GO:1902846(positive regulation of mitotic spindle elongation);GO:1905820(positive regulation of chromosome separation);GO:0055028(cortical microtubule);GO:0061673(mitotic spindle astral microtubule);GO:1905720(cytoplasmic microtubule bundle);GO:0051321(meiotic cell cycle);GO:0060487(lung epithelial cell differentiation);GO:0030425(dendrite);GO:0043025(neuronal cell body);GO:0045177(apical part of cell);GO:0045177(apical part of cell)","NA","NA","NA","nuclear mitotic apparatus protein 1 [Source:HGNC Symbol;Acc:HGNC:8059]",{"v":11.8676165241595,"d":"11.87"},{"v":3.90832762580477,"d":"3.91"},{"v":3.03649480299539,"d":"3.04"},{"v":1.60240689999675,"d":"1.60"},{"v":0.0451141604442067,"d":"0.05"},{"v":0.508634782751109,"d":"0.51"},"up","yes"]
["MSTRG.2228","RPL27A","ENST00000532359;ENST00000531978;ENST00000530022;ENST00000314138;ENST00000525981;ENST00000524496;ENST00000534599;ENST00000526562;ENST00000529227;ENST00000530913;ENST00000530585","GO:0003723(RNA binding);GO:0016020(membrane);GO:0006412(translation);GO:0005783(endoplasmic reticulum);GO:0005829(cytosol);GO:0030529(intracellular ribonucleoprotein complex);GO:0005622(intracellular);GO:0003735(structural constituent of ribosome);GO:0005840(ribosome);GO:0005515(protein binding);GO:0015934(large ribosomal subunit);GO:0002181(cytoplasmic translation);GO:0006413(translational initiation);GO:0006364(rRNA processing);GO:0000184(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay);GO:0019083(viral transcription);GO:0006614(SRP-dependent cotranslational protein targeting to membrane);GO:0022625(cytosolic large ribosomal subunit);GO:0022625(cytosolic large ribosomal subunit)","03010(Ribosome);03010(Ribosome)","K02900","NA","ribosomal protein L27a [Source:HGNC Symbol;Acc:HGNC:10329]",{"v":51.4229120497706,"d":"51.42"},{"v":107.347812136244,"d":"107.35"},{"v":0.479030834690003,"d":"0.48"},{"v":-1.06180957123781,"d":"-1.06"},{"v":0.045156502283337,"d":"0.05"},{"v":0.508634782751109,"d":"0.51"},"down","yes"]
["MSTRG.7571","GZMM","ENST00000264553;ENST00000592501","GO:0016787(hydrolase activity);GO:0008233(peptidase activity);GO:0006508(proteolysis);GO:0004252(serine-type endopeptidase activity);GO:0008236(serine-type peptidase activity);GO:0008219(cell death);GO:0016020(membrane);GO:0005576(extracellular region);GO:0006915(apoptotic process);GO:0002376(immune system process);GO:0045087(innate immune response);GO:0019835(cytolysis);GO:0005515(protein binding);GO:0004175(endopeptidase activity);GO:0004175(endopeptidase activity)","NA","NA","NA","granzyme M [Source:HGNC Symbol;Acc:HGNC:4712]",{"v":21.3876730539682,"d":"21.39"},{"v":44.7474894656085,"d":"44.75"},{"v":0.477963642416321,"d":"0.48"},{"v":-1.06502721496713,"d":"-1.07"},{"v":0.0452778553700795,"d":"0.05"},{"v":0.509254522962293,"d":"0.51"},"down","yes"]
["ENSG00000152217","SETBP1","ENST00000282030;ENST00000426838","GO:0005634(nucleus);GO:0005829(cytosol);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0016604(nuclear body);GO:0016604(nuclear body)","NA","NA","NA","SET binding protein 1 [Source:HGNC Symbol;Acc:HGNC:15573]",{"v":0.742345091202583,"d":"0.74"},{"v":0.240041474934983,"d":"0.24"},{"v":3.09257011274261,"d":"3.09"},{"v":1.62880630341812,"d":"1.63"},{"v":0.0452992269198354,"d":"0.05"},{"v":0.509254522962293,"d":"0.51"},"up","yes"]
["MSTRG.3346","AC011603.2","MSTRG.3346.1;ENST00000547387;ENST00000547712;ENST00000548149;ENST00000552893;ENST00000551496","NA","NA","NA","NA",null,{"v":2.23160757495789,"d":"2.23"},{"v":4.72174786412128,"d":"4.72"},{"v":0.472623197844808,"d":"0.47"},{"v":-1.08123765179163,"d":"-1.08"},{"v":0.0455397795548183,"d":"0.05"},{"v":0.511463694361803,"d":"0.51"},"down","yes"]
["ENSG00000198625","MDM4","ENST00000367182;ENST00000391947;ENST00000367183;ENST00000462012;ENST00000367179;ENST00000463049;ENST00000470797;ENST00000470908;ENST00000367180;ENST00000454264","GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0043066(negative regulation of apoptotic process);GO:0016567(protein ubiquitination);GO:0008270(zinc ion binding);GO:0005515(protein binding);GO:0071157(negative regulation of cell cycle arrest);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0061630(ubiquitin protein ligase activity);GO:0006977(DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest);GO:0005654(nucleoplasm);GO:0050821(protein stabilization);GO:0016579(protein deubiquitination);GO:0008283(cell proliferation);GO:0019899(enzyme binding);GO:1901796(regulation of signal transduction by p53 class mediator);GO:0008285(negative regulation of cell proliferation);GO:0042177(negative regulation of protein catabolic process);GO:0006461(protein complex assembly);GO:0030330(DNA damage response, signal transduction by p53 class mediator);GO:0045023(G0 to G1 transition);GO:0071456(cellular response to hypoxia);GO:0071456(cellular response to hypoxia)","04115(p53 signaling pathway);05206(MicroRNAs in cancer);05206(MicroRNAs in cancer)","K10127","NA","MDM4, p53 regulator [Source:HGNC Symbol;Acc:HGNC:6974]",{"v":4.36000017996003,"d":"4.36"},{"v":1.43321730087209,"d":"1.43"},{"v":3.04210685798102,"d":"3.04"},{"v":1.60507083050214,"d":"1.61"},{"v":0.0456155974095488,"d":"0.05"},{"v":0.51182022484743,"d":"0.51"},"up","yes"]
["MSTRG.6209","COX4I1","ENST00000253452;ENST00000562336;ENST00000568339;ENST00000561569;ENST00000569997;ENST00000568794;ENST00000564544;ENST00000564648;ENST00000564903;ENST00000566115;ENST00000566617;ENST00000566405;ENST00000563774;ENST00000567266;ENST00000562929;ENST00000565078;ENST00000567241","GO:1902600(hydrogen ion transmembrane transport);GO:0004129(cytochrome-c oxidase activity);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005634(nucleus);GO:0005739(mitochondrion);GO:0005743(mitochondrial inner membrane);GO:0005515(protein binding);GO:0070062(extracellular exosome);GO:0006123(mitochondrial electron transport, cytochrome c to oxygen);GO:0006091(generation of precursor metabolites and energy);GO:0005751(mitochondrial respiratory chain complex IV);GO:0007584(response to nutrient);GO:0031966(mitochondrial membrane);GO:0031966(mitochondrial membrane)","00190(Oxidative phosphorylation);04260(Cardiac muscle contraction);05010(Alzheimer's disease);05012(Parkinson's disease);05016(Huntington's disease);04932(Non-alcoholic fatty liver disease (NAFLD));04932(Non-alcoholic fatty liver disease (NAFLD))","K02263","NA","cytochrome c oxidase subunit 4I1 [Source:HGNC Symbol;Acc:HGNC:2265]",{"v":23.2806232608514,"d":"23.28"},{"v":48.5234494198664,"d":"48.52"},{"v":0.479780879949559,"d":"0.48"},{"v":-1.05955242986041,"d":"-1.06"},{"v":0.0456716277980028,"d":"0.05"},{"v":0.511954260249234,"d":"0.51"},"down","yes"]
["ENSG00000113734","BNIP1","ENST00000351486;ENST00000519459;ENST00000231668","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005739(mitochondrion);GO:0006915(apoptotic process);GO:0006914(autophagy);GO:0016192(vesicle-mediated transport);GO:0005515(protein binding);GO:0043231(intracellular membrane-bounded organelle);GO:0006890(retrograde vesicle-mediated transport, Golgi to ER);GO:0043066(negative regulation of apoptotic process);GO:0005737(cytoplasm);GO:0005635(nuclear envelope);GO:0031201(SNARE complex);GO:0097194(execution phase of apoptosis);GO:0005484(SNAP receptor activity);GO:0007029(endoplasmic reticulum organization);GO:0016320(endoplasmic reticulum membrane fusion);GO:0030176(integral component of endoplasmic reticulum membrane);GO:0030176(integral component of endoplasmic reticulum membrane)","04130(SNARE interactions in vesicular transport);04130(SNARE interactions in vesicular transport)","K08497","NA","BCL2 interacting protein 1 [Source:HGNC Symbol;Acc:HGNC:1082]",{"v":1.08632197540984,"d":"1.09"},{"v":2.31107645614754,"d":"2.31"},{"v":0.470050210809853,"d":"0.47"},{"v":-1.08911322103906,"d":"-1.09"},{"v":0.0457251644818572,"d":"0.05"},{"v":0.512060111020066,"d":"0.51"},"down","yes"]
["MSTRG.3694","ACACB","ENST00000538526;ENST00000542524;ENST00000377848;ENST00000377854;ENST00000544651;ENST00000396233;ENST00000546328;ENST00000537279;ENST00000338432;ENST00000537347;ENST00000544726;ENST00000536440;ENST00000534852","GO:0005634(nucleus);GO:0016020(membrane);GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0003824(catalytic activity);GO:0006629(lipid metabolic process);GO:0006631(fatty acid metabolic process);GO:0006633(fatty acid biosynthetic process);GO:0005739(mitochondrion);GO:0003989(acetyl-CoA carboxylase activity);GO:0004075(biotin carboxylase activity);GO:0016874(ligase activity);GO:0005515(protein binding);GO:0008152(metabolic process);GO:0005829(cytosol);GO:0012505(endomembrane system);GO:0051289(protein homotetramerization);GO:0005741(mitochondrial outer membrane);GO:0009374(biotin binding);GO:0006084(acetyl-CoA metabolic process);GO:0006768(biotin metabolic process);GO:0006853(carnitine shuttle);GO:0010629(negative regulation of gene expression);GO:0010884(positive regulation of lipid storage);GO:0010906(regulation of glucose metabolic process);GO:0014070(response to organic cyclic compound);GO:0031325(positive regulation of cellular metabolic process);GO:0031667(response to nutrient levels);GO:0031999(negative regulation of fatty acid beta-oxidation);GO:0042493(response to drug);GO:0043086(negative regulation of catalytic activity);GO:0045540(regulation of cholesterol biosynthetic process);GO:0046322(negative regulation of fatty acid oxidation);GO:0050995(negative regulation of lipid catabolic process);GO:0060421(positive regulation of heart growth);GO:0097009(energy homeostasis);GO:2001295(malonyl-CoA biosynthetic process);GO:2001295(malonyl-CoA biosynthetic process)","00620(Pyruvate metabolism);00640(Propanoate metabolism);00061(Fatty acid biosynthesis);00254(Aflatoxin biosynthesis);04152(AMPK signaling pathway);04910(Insulin signaling pathway);04922(Glucagon signaling pathway);04920(Adipocytokine signaling pathway);04931(Insulin resistance);04931(Insulin resistance)","K01946","EC:6.4.1.2;EC:6.3.4.14","acetyl-CoA carboxylase beta [Source:HGNC Symbol;Acc:HGNC:85]",{"v":0.784366581178904,"d":"0.78"},{"v":0.255300991658049,"d":"0.26"},{"v":3.07232093414462,"d":"3.07"},{"v":1.61932892761996,"d":"1.62"},{"v":0.0457931320528205,"d":"0.05"},{"v":0.512327208602509,"d":"0.51"},"up","yes"]
["MSTRG.2858","AP002518.2","MSTRG.2858.1","NA","NA","NA","NA",null,{"v":2.942338,"d":"2.94"},{"v":0.94245,"d":"0.94"},{"v":3.12200965568465,"d":"3.12"},{"v":1.64247499925907,"d":"1.64"},{"v":0.0459420185536759,"d":"0.05"},{"v":0.512680310505601,"d":"0.51"},"up","yes"]
["MSTRG.5252","TLE3","ENST00000557997;ENST00000557907;ENST00000451782;ENST00000558939;ENST00000317509;ENST00000557815;ENST00000559048;ENST00000560525;ENST00000559929;ENST00000558379;ENST00000557919;ENST00000558201;ENST00000557984;ENST00000627388;ENST00000560589;ENST00000537387;ENST00000560939;ENST00000561453;ENST00000539550;ENST00000559191;ENST00000560996;ENST00000559826;ENST00000542329;ENST00000559608;ENST00000440567","GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0016055(Wnt signaling pathway);GO:0005515(protein binding);GO:0007165(signal transduction);GO:1904837(beta-catenin-TCF complex assembly);GO:0009887(animal organ morphogenesis);GO:0009887(animal organ morphogenesis)","NA","NA","NA","transducin like enhancer of split 3 [Source:HGNC Symbol;Acc:HGNC:11839]",{"v":14.2896558168434,"d":"14.29"},{"v":4.71829072304892,"d":"4.72"},{"v":3.02856620238304,"d":"3.03"},{"v":1.59863494806078,"d":"1.60"},{"v":0.045946377633074,"d":"0.05"},{"v":0.512680310505601,"d":"0.51"},"up","yes"]
["MSTRG.2588","MRPL11","ENST00000430466;ENST00000310999;ENST00000524576;ENST00000329819;ENST00000534488;ENST00000528272","GO:0003723(RNA binding);GO:0006412(translation);GO:0005739(mitochondrion);GO:0030529(intracellular ribonucleoprotein complex);GO:0003735(structural constituent of ribosome);GO:0005840(ribosome);GO:0005515(protein binding);GO:0019843(rRNA binding);GO:0000027(ribosomal large subunit assembly);GO:0005743(mitochondrial inner membrane);GO:0070125(mitochondrial translational elongation);GO:0070126(mitochondrial translational termination);GO:0005761(mitochondrial ribosome);GO:0005762(mitochondrial large ribosomal subunit);GO:0005762(mitochondrial large ribosomal subunit)","03010(Ribosome);03010(Ribosome)","K02867","NA","mitochondrial ribosomal protein L11 [Source:HGNC Symbol;Acc:HGNC:14042]",{"v":3.86459006931863,"d":"3.86"},{"v":8.09269424182749,"d":"8.09"},{"v":0.477540600674656,"d":"0.48"},{"v":-1.06630469807007,"d":"-1.07"},{"v":0.0459571345247852,"d":"0.05"},{"v":0.512680310505601,"d":"0.51"},"down","yes"]
["MSTRG.15286","TIMM17B","ENST00000465150;ENST00000376582;ENST00000464663;ENST00000472645;ENST00000495490;MSTRG.15286.1;ENST00000490755;ENST00000466995","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0006886(intracellular protein transport);GO:0015031(protein transport);GO:0015450(P-P-bond-hydrolysis-driven protein transmembrane transporter activity);GO:0005743(mitochondrial inner membrane);GO:0005739(mitochondrion);GO:0005744(mitochondrial inner membrane presequence translocase complex);GO:0005515(protein binding);GO:0015266(protein channel activity);GO:0006626(protein targeting to mitochondrion);GO:0030150(protein import into mitochondrial matrix);GO:0031305(integral component of mitochondrial inner membrane);GO:0031305(integral component of mitochondrial inner membrane)","NA","NA","NA","translocase of inner mitochondrial membrane 17B [Source:HGNC Symbol;Acc:HGNC:17310]",{"v":3.67315019713532,"d":"3.67"},{"v":7.70227182434979,"d":"7.70"},{"v":0.476891789968137,"d":"0.48"},{"v":-1.06826614896409,"d":"-1.07"},{"v":0.0460200292767924,"d":"0.05"},{"v":0.512889251431276,"d":"0.51"},"down","yes"]
["MSTRG.7659","MRPL54","ENST00000330133;ENST00000589174","GO:0003723(RNA binding);GO:0030529(intracellular ribonucleoprotein complex);GO:0005840(ribosome);GO:0005739(mitochondrion);GO:0005743(mitochondrial inner membrane);GO:0070125(mitochondrial translational elongation);GO:0070126(mitochondrial translational termination);GO:0005762(mitochondrial large ribosomal subunit);GO:0005762(mitochondrial large ribosomal subunit)","NA","NA","NA","mitochondrial ribosomal protein L54 [Source:HGNC Symbol;Acc:HGNC:16685]",{"v":5.99203642472582,"d":"5.99"},{"v":12.5556128504487,"d":"12.56"},{"v":0.477239661344901,"d":"0.48"},{"v":-1.06721415066412,"d":"-1.07"},{"v":0.0462021197090886,"d":"0.05"},{"v":0.514424943606564,"d":"0.51"},"down","yes"]
["MSTRG.7824","PLPPR2","ENST00000251473;ENST00000591608;ENST00000587801;ENST00000588360;ENST00000586380;ENST00000591329;ENST00000588196;ENST00000586431","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016787(hydrolase activity);GO:0005887(integral component of plasma membrane);GO:0007165(signal transduction);GO:0008195(phosphatidate phosphatase activity);GO:0042577(lipid phosphatase activity);GO:0006644(phospholipid metabolic process);GO:0046839(phospholipid dephosphorylation);GO:0046839(phospholipid dephosphorylation)","NA","NA","NA","phospholipid phosphatase related 2 [Source:HGNC Symbol;Acc:HGNC:29566]",{"v":16.0555560672166,"d":"16.06"},{"v":5.30394079193401,"d":"5.30"},{"v":3.02709941476593,"d":"3.03"},{"v":1.59793605634634,"d":"1.60"},{"v":0.0462782641766129,"d":"0.05"},{"v":0.514676318256376,"d":"0.51"},"up","yes"]
["ENSG00000068024","HDAC4","ENST00000543185;ENST00000495497;ENST00000544989;ENST00000460235;ENST00000493582;ENST00000553145;ENST00000445704;ENST00000487617;ENST00000446876;ENST00000496347;ENST00000345617;ENST00000535493;ENST00000494800;ENST00000454542;ENST00000430200;ENST00000463007","GO:0008284(positive regulation of cell proliferation);GO:0051091(positive regulation of sequence-specific DNA binding transcription factor activity);GO:0010832(negative regulation of myotube differentiation);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0005737(cytoplasm);GO:0043433(negative regulation of sequence-specific DNA binding transcription factor activity);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0004407(histone deacetylase activity);GO:0016787(hydrolase activity);GO:0032041(NAD-dependent histone deacetylase activity (H3-K14 specific));GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0016569(covalent chromatin modification);GO:0006476(protein deacetylation);GO:0005515(protein binding);GO:0007399(nervous system development);GO:0006325(chromatin organization);GO:0006954(inflammatory response);GO:0001047(core promoter binding);GO:0016575(histone deacetylation);GO:0042113(B cell activation);GO:0000118(histone deacetylase complex);GO:0045893(positive regulation of transcription, DNA-templated);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0045892(negative regulation of transcription, DNA-templated);GO:0044212(transcription regulatory region DNA binding);GO:0006338(chromatin remodeling);GO:0014898(cardiac muscle hypertrophy in response to stress);GO:0042826(histone deacetylase binding);GO:0017053(transcriptional repressor complex);GO:0043565(sequence-specific DNA binding);GO:0070555(response to interleukin-1);GO:0008134(transcription factor binding);GO:0040029(regulation of gene expression, epigenetic);GO:0033235(positive regulation of protein sumoylation);GO:0008270(zinc ion binding);GO:0030955(potassium ion binding);GO:0030183(B cell differentiation);GO:0043393(regulation of protein binding);GO:0070491(repressing transcription factor binding);GO:0033613(activating transcription factor binding);GO:0001025(RNA polymerase III transcription factor binding);GO:0003677(DNA binding);GO:0003682(chromatin binding);GO:0003714(transcription corepressor activity);GO:0019901(protein kinase binding);GO:0033558(protein deacetylase activity);GO:0001501(skeletal system development);GO:0002076(osteoblast development);GO:0008285(negative regulation of cell proliferation);GO:0010592(positive regulation of lamellipodium assembly);GO:0010882(regulation of cardiac muscle contraction by calcium ion signaling);GO:0014894(response to denervation involved in regulation of muscle adaptation);GO:0014911(positive regulation of smooth muscle cell migration);GO:0034983(peptidyl-lysine deacetylation);GO:0042493(response to drug);GO:0043525(positive regulation of neuron apoptotic process);GO:0045668(negative regulation of osteoblast differentiation);GO:0045820(negative regulation of glycolytic process);GO:0048661(positive regulation of smooth muscle cell proliferation);GO:0048742(regulation of skeletal muscle fiber development);GO:0051153(regulation of striated muscle cell differentiation);GO:0070932(histone H3 deacetylation);GO:0070933(histone H4 deacetylation);GO:0071260(cellular response to mechanical stimulus);GO:0071356(cellular response to tumor necrosis factor);GO:0071374(cellular response to parathyroid hormone stimulus);GO:1902894(negative regulation of pri-miRNA transcription from RNA polymerase II promoter);GO:1903428(positive regulation of reactive oxygen species biosynthetic process);GO:0030017(sarcomere);GO:0030018(Z disc);GO:0031594(neuromuscular junction);GO:0031672(A band);GO:0042641(actomyosin);GO:0043234(protein complex);GO:0043234(protein complex)","04371(Apelin signaling pathway);05206(MicroRNAs in cancer);05203(Viral carcinogenesis);05034(Alcoholism);05169(Epstein-Barr virus infection);05165(Human papillomavirus infection);05165(Human papillomavirus infection)","K11406","EC:3.5.1.98","histone deacetylase 4 [Source:HGNC Symbol;Acc:HGNC:14063]",{"v":3.79942225800419,"d":"3.80"},{"v":1.25476292826152,"d":"1.25"},{"v":3.02800008864488,"d":"3.03"},{"v":1.59836524755863,"d":"1.60"},{"v":0.0463334079832142,"d":"0.05"},{"v":0.514676318256376,"d":"0.51"},"up","yes"]
["MSTRG.8126","DYRK1B","ENST00000430012;ENST00000323039;ENST00000348817;ENST00000601972;ENST00000601696;ENST00000597639;ENST00000593685","GO:0005634(nucleus);GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0004713(protein tyrosine kinase activity);GO:0018108(peptidyl-tyrosine phosphorylation);GO:0007520(myoblast fusion);GO:0005515(protein binding);GO:0003713(transcription coactivator activity);GO:0045893(positive regulation of transcription, DNA-templated);GO:0060612(adipose tissue development);GO:0004712(protein serine/threonine/tyrosine kinase activity);GO:0004712(protein serine/threonine/tyrosine kinase activity)","NA","NA","NA","dual specificity tyrosine phosphorylation regulated kinase 1B [Source:HGNC Symbol;Acc:HGNC:3092]",{"v":5.29892469893484,"d":"5.30"},{"v":1.74042357738095,"d":"1.74"},{"v":3.04461785498726,"d":"3.04"},{"v":1.60626115972021,"d":"1.61"},{"v":0.0464343974238032,"d":"0.05"},{"v":0.514676318256376,"d":"0.51"},"up","yes"]
["MSTRG.3172","KLRC2;KLRC3;KLRC1;AC068775.2","ENST00000381901;ENST00000396439;ENST00000359151;ENST00000347831;ENST00000381902;ENST00000536833;ENST00000536188;ENST00000408006;ENST00000381903;ENST00000537699;ENST00000544822;ENST00000535069;ENST00000537017;ENST00000543893;ENST00000539033","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0030246(carbohydrate binding);GO:0005515(protein binding);GO:0005886(plasma membrane);GO:0045087(innate immune response);GO:0005887(integral component of plasma membrane);GO:0007165(signal transduction);GO:0043235(receptor complex);GO:0004888(transmembrane signaling receptor activity);GO:0006968(cellular defense response);GO:0023024(MHC class I protein complex binding);GO:1990405(protein antigen binding);GO:0002228(natural killer cell mediated immunity);GO:0050776(regulation of immune response);GO:0007166(cell surface receptor signaling pathway);GO:0030246(carbohydrate binding)","04650(Natural killer cell mediated cytotoxicity);04612(Antigen processing and presentation);05332(Graft-versus-host disease);05332(Graft-versus-host disease)","K06541","NA","killer cell lectin like receptor C2 [Source:HGNC Symbol;Acc:HGNC:6375];killer cell lectin like receptor C3 [Source:HGNC Symbol;Acc:HGNC:6376];killer cell lectin like receptor C1 [Source:HGNC Symbol;Acc:HGNC:6374]",{"v":3.74694615105342,"d":"3.75"},{"v":7.81003540500376,"d":"7.81"},{"v":0.479760456483054,"d":"0.48"},{"v":-1.05961384427317,"d":"-1.06"},{"v":0.0464642816906205,"d":"0.05"},{"v":0.514676318256376,"d":"0.51"},"down","yes"]
["MSTRG.565","PRPF38A","ENST00000257181;ENST00000487160","GO:0003723(RNA binding);GO:0006397(mRNA processing);GO:0008380(RNA splicing);GO:0005634(nucleus);GO:0031965(nuclear membrane);GO:0005515(protein binding);GO:0005681(spliceosomal complex);GO:0005654(nucleoplasm);GO:0000398(mRNA splicing, via spliceosome);GO:0071011(precatalytic spliceosome);GO:0071011(precatalytic spliceosome)","03040(Spliceosome);03040(Spliceosome)","K12849","NA","pre-mRNA processing factor 38A [Source:HGNC Symbol;Acc:HGNC:25930]",{"v":2.75506116613644,"d":"2.76"},{"v":5.73849618204313,"d":"5.74"},{"v":0.4801015943441,"d":"0.48"},{"v":-1.05858836791292,"d":"-1.06"},{"v":0.0465085343260961,"d":"0.05"},{"v":0.514676318256376,"d":"0.51"},"down","yes"]
["MSTRG.15247","USP9X","ENST00000378308;ENST00000324545;MSTRG.15247.1;ENST00000463829;ENST00000485180;ENST00000487625;ENST00000465386","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0016579(protein deubiquitination);GO:0016787(hydrolase activity);GO:0051301(cell division);GO:0042995(cell projection);GO:0005515(protein binding);GO:0008233(peptidase activity);GO:0008234(cysteine-type peptidase activity);GO:0006508(proteolysis);GO:0007049(cell cycle);GO:0006511(ubiquitin-dependent protein catabolic process);GO:0036459(thiol-dependent ubiquitinyl hydrolase activity);GO:0007059(chromosome segregation);GO:0016567(protein ubiquitination);GO:0005829(cytosol);GO:0030426(growth cone);GO:0044267(cellular protein metabolic process);GO:0030509(BMP signaling pathway);GO:0007179(transforming growth factor beta receptor signaling pathway);GO:0070410(co-SMAD binding);GO:0001764(neuron migration);GO:0007292(female gamete generation);GO:0004197(cysteine-type endopeptidase activity);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0048675(axon extension);GO:0048675(axon extension)","NA","NA","NA","ubiquitin specific peptidase 9, X-linked [Source:HGNC Symbol;Acc:HGNC:12632]",{"v":9.54404883813559,"d":"9.54"},{"v":3.16266817026836,"d":"3.16"},{"v":3.01772058411229,"d":"3.02"},{"v":1.59345923045791,"d":"1.59"},{"v":0.0465606857935872,"d":"0.05"},{"v":0.514676318256376,"d":"0.51"},"up","yes"]
["MSTRG.12700","E2F3","ENST00000535432;MSTRG.12700.4;ENST00000613242;ENST00000346618","GO:0005634(nucleus);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0046983(protein dimerization activity);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0005515(protein binding);GO:0007049(cell cycle);GO:0005667(transcription factor complex);GO:0001047(core promoter binding);GO:0001228(transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding);GO:0043565(sequence-specific DNA binding);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0000977(RNA polymerase II regulatory region sequence-specific DNA binding);GO:0006367(transcription initiation from RNA polymerase II promoter);GO:0008284(positive regulation of cell proliferation);GO:0045893(positive regulation of transcription, DNA-templated);GO:0070345(negative regulation of fat cell proliferation);GO:0090575(RNA polymerase II transcription factor complex);GO:0090575(RNA polymerase II transcription factor complex)","04110(Cell cycle);04218(Cellular senescence);05200(Pathways in cancer);05206(MicroRNAs in cancer);05212(Pancreatic cancer);05225(Hepatocellular carcinoma);05226(Gastric cancer);05214(Glioma);05220(Chronic myeloid leukemia);05218(Melanoma);05219(Bladder cancer);05215(Prostate cancer);05224(Breast cancer);05222(Small cell lung cancer);05223(Non-small cell lung cancer);05166(HTLV-I infection);05161(Hepatitis B);05167(Kaposi's sarcoma-associated herpesvirus infection);01522(Endocrine resistance);01522(Endocrine resistance)","K06620","NA","E2F transcription factor 3 [Source:HGNC Symbol;Acc:HGNC:3115]",{"v":7.92841206700232,"d":"7.93"},{"v":2.6238989359024,"d":"2.62"},{"v":3.02161487949063,"d":"3.02"},{"v":1.59531979324421,"d":"1.60"},{"v":0.0466609668866388,"d":"0.05"},{"v":0.514676318256376,"d":"0.51"},"up","yes"]
["MSTRG.15402","TMEM164","ENST00000372073;ENST00000372072;MSTRG.15402.4;ENST00000372068;ENST00000288381;ENST00000464177;ENST00000471255;ENST00000461715","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016021(integral component of membrane)","NA","NA","NA","transmembrane protein 164 [Source:HGNC Symbol;Acc:HGNC:26217]",{"v":5.52652496187149,"d":"5.53"},{"v":11.4762760984354,"d":"11.48"},{"v":0.481560822907087,"d":"0.48"},{"v":-1.05421006760847,"d":"-1.05"},{"v":0.046679678734697,"d":"0.05"},{"v":0.514676318256376,"d":"0.51"},"down","yes"]
["ENSG00000100298","APOBEC3H","ENST00000442487;ENST00000348946;ENST00000613677;ENST00000401756","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0016787(hydrolase activity);GO:0003824(catalytic activity);GO:0002376(immune system process);GO:0045087(innate immune response);GO:0051607(defense response to virus);GO:0016814(hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines);GO:0000932(P-body);GO:0005515(protein binding);GO:0004126(cytidine deaminase activity);GO:0009972(cytidine deamination);GO:0010529(negative regulation of transposition);GO:0070383(DNA cytosine deamination);GO:0045869(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate);GO:0048525(negative regulation of viral process);GO:0048525(negative regulation of viral process)","NA","NA","NA","apolipoprotein B mRNA editing enzyme catalytic subunit 3H [Source:HGNC Symbol;Acc:HGNC:24100]",{"v":0.701333733013589,"d":"0.70"},{"v":1.53333012310152,"d":"1.53"},{"v":0.457392522619315,"d":"0.46"},{"v":-1.12849531389556,"d":"-1.13"},{"v":0.0466853524583687,"d":"0.05"},{"v":0.514676318256376,"d":"0.51"},"down","yes"]
["ENSG00000274588","DGKK","ENST00000611977","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0035556(intracellular signal transduction);GO:0008152(metabolic process);GO:0003951(NAD+ kinase activity);GO:0004143(diacylglycerol kinase activity);GO:0007205(protein kinase C-activating G-protein coupled receptor signaling pathway);GO:0005886(plasma membrane);GO:0030168(platelet activation);GO:0006979(response to oxidative stress);GO:0046339(diacylglycerol metabolic process)","00561(Glycerolipid metabolism);00564(Glycerophospholipid metabolism);04070(Phosphatidylinositol signaling system);04072(Phospholipase D signaling pathway);05231(Choline metabolism in cancer)","K00901","EC:2.7.1.107","diacylglycerol kinase kappa [Source:HGNC Symbol;Acc:HGNC:32395]",{"v":0.380877,"d":"0.38"},{"v":0.1208,"d":"0.12"},{"v":3.15295529801325,"d":"3.15"},{"v":1.65670471591666,"d":"1.66"},{"v":0.0467024223418559,"d":"0.05"},{"v":0.514676318256376,"d":"0.51"},"up","yes"]
["MSTRG.15312","HSD17B10","ENST00000168216;ENST00000375298;ENST00000477706;ENST00000375304;ENST00000495986","GO:0003723(RNA binding);GO:0008033(tRNA processing);GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0005739(mitochondrion);GO:0005515(protein binding);GO:0005759(mitochondrial matrix);GO:0005886(plasma membrane);GO:0005737(cytoplasm);GO:0006629(lipid metabolic process);GO:0009083(branched-chain amino acid catabolic process);GO:0090646(mitochondrial tRNA processing);GO:0030678(mitochondrial ribonuclease P complex);GO:0007005(mitochondrion organization);GO:0030283(testosterone dehydrogenase [NAD(P)] activity);GO:0003857(3-hydroxyacyl-CoA dehydrogenase activity);GO:0070901(mitochondrial tRNA methylation);GO:0008709(cholate 7-alpha-dehydrogenase activity);GO:0047015(3-hydroxy-2-methylbutyryl-CoA dehydrogenase activity);GO:0047015(3-hydroxy-2-methylbutyryl-CoA dehydrogenase activity)","00280(Valine, leucine and isoleucine degradation);05010(Alzheimer's disease);05010(Alzheimer's disease)","K08683","EC:1.1.1.35;EC:1.1.1.178","hydroxysteroid 17-beta dehydrogenase 10 [Source:HGNC Symbol;Acc:HGNC:4800]",{"v":10.3647756017937,"d":"10.36"},{"v":21.5804040125561,"d":"21.58"},{"v":0.480286448565243,"d":"0.48"},{"v":-1.05803299183677,"d":"-1.06"},{"v":0.0467233196582767,"d":"0.05"},{"v":0.514676318256376,"d":"0.51"},"down","yes"]
["MSTRG.13011","TREML1","ENST00000373127;ENST00000426005;ENST00000437044;ENST00000590581","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005886(plasma membrane);GO:0045087(innate immune response);GO:0050776(regulation of immune response);GO:0050776(regulation of immune response)","NA","NA","NA","triggering receptor expressed on myeloid cells like 1 [Source:HGNC Symbol;Acc:HGNC:20434]",{"v":6.67427436412677,"d":"6.67"},{"v":13.896123604855,"d":"13.90"},{"v":0.480297567430598,"d":"0.48"},{"v":-1.05799959313007,"d":"-1.06"},{"v":0.0468122450436283,"d":"0.05"},{"v":0.514676318256376,"d":"0.51"},"down","yes"]
["ENSG00000282508","LINC01002","ENST00000631858;ENST00000631401;ENST00000632102;ENST00000633808;ENST00000632075;ENST00000632351;ENST00000631764;ENST00000632086;ENST00000632747;ENST00000633671;ENST00000633592;ENST00000634022;ENST00000632624;ENST00000631988;ENST00000633151;ENST00000632790;ENST00000631772;ENST00000632203;ENST00000633295;ENST00000631484;ENST00000632405;ENST00000633951;ENST00000631644;ENST00000631797;ENST00000631832;ENST00000633522;ENST00000633344;ENST00000631864;ENST00000633109;ENST00000633179;ENST00000633363","NA","NA","NA","NA","long intergenic non-protein coding RNA 1002 [Source:HGNC Symbol;Acc:HGNC:38538]",{"v":2.00514786864134,"d":"2.01"},{"v":0.651195740631037,"d":"0.65"},{"v":3.07917841523083,"d":"3.08"},{"v":1.62254546313181,"d":"1.62"},{"v":0.0468377564385336,"d":"0.05"},{"v":0.514676318256376,"d":"0.51"},"up","yes"]
["MSTRG.463","PPT1","ENST00000641471;ENST00000439754;ENST00000642050;ENST00000641691;ENST00000641319;MSTRG.463.1;ENST00000527311;ENST00000641924;ENST00000530704;ENST00000641083;ENST00000372775;ENST00000529905;ENST00000433473;ENST00000641381;ENST00000449045;ENST00000526547;ENST00000372779;ENST00000641236","GO:0005615(extracellular space);GO:0044257(cellular protein catabolic process);GO:0005764(lysosome);GO:0043025(neuronal cell body);GO:0030424(axon);GO:0007601(visual perception);GO:0030425(dendrite);GO:0008474(palmitoyl-(protein) hydrolase activity);GO:0002084(protein depalmitoylation);GO:0007040(lysosome organization);GO:0007269(neurotransmitter secretion);GO:0007625(grooming behavior);GO:0008306(associative learning);GO:0008344(adult locomotory behavior);GO:0032429(regulation of phospholipase A2 activity);GO:0044265(cellular macromolecule catabolic process);GO:0008021(synaptic vesicle);GO:0043005(neuron projection);GO:0045202(synapse);GO:0098599(palmitoyl hydrolase activity);GO:0005634(nucleus);GO:0016020(membrane);GO:0015031(protein transport);GO:0016787(hydrolase activity);GO:0005794(Golgi apparatus);GO:0016042(lipid catabolic process);GO:0005829(cytosol);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0007399(nervous system development);GO:0045121(membrane raft);GO:0050896(response to stimulus);GO:0048666(neuron development);GO:0070062(extracellular exosome);GO:0043524(negative regulation of neuron apoptotic process);GO:0016290(palmitoyl-CoA hydrolase activity);GO:0043066(negative regulation of apoptotic process);GO:0030308(negative regulation of cell growth);GO:0048260(positive regulation of receptor-mediated endocytosis);GO:0007268(chemical synaptic transmission);GO:0007420(brain development);GO:0043202(lysosomal lumen);GO:0046949(fatty-acyl-CoA biosynthetic process);GO:0030163(protein catabolic process);GO:0031579(membrane raft organization);GO:0007042(lysosomal lumen acidification);GO:0030149(sphingolipid catabolic process);GO:0050803(regulation of synapse structure or activity);GO:0006898(receptor-mediated endocytosis);GO:0006907(pinocytosis);GO:0048549(positive regulation of pinocytosis);GO:0051181(cofactor transport);GO:0051186(cofactor metabolic process);GO:0051186(cofactor metabolic process)","00062(Fatty acid elongation);04142(Lysosome);04142(Lysosome)","K01074","EC:3.1.2.22","palmitoyl-protein thioesterase 1 [Source:HGNC Symbol;Acc:HGNC:9325]",{"v":15.3117644051453,"d":"15.31"},{"v":31.7576148790259,"d":"31.76"},{"v":0.482144659272188,"d":"0.48"},{"v":-1.05246202747122,"d":"-1.05"},{"v":0.0468480347354828,"d":"0.05"},{"v":0.514676318256376,"d":"0.51"},"down","yes"]
["MSTRG.9009","RPL31","ENST00000264258;ENST00000409320;ENST00000456292;ENST00000409733;ENST00000409028;ENST00000441435;ENST00000409038;ENST00000409650;ENST00000409711;ENST00000409000;ENST00000419276","GO:0003723(RNA binding);GO:0016020(membrane);GO:0006412(translation);GO:0030529(intracellular ribonucleoprotein complex);GO:0005622(intracellular);GO:0003735(structural constituent of ribosome);GO:0005840(ribosome);GO:0005925(focal adhesion);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0005515(protein binding);GO:0002181(cytoplasmic translation);GO:0006413(translational initiation);GO:0006364(rRNA processing);GO:0000184(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay);GO:0019083(viral transcription);GO:0006614(SRP-dependent cotranslational protein targeting to membrane);GO:0022625(cytosolic large ribosomal subunit);GO:0022625(cytosolic large ribosomal subunit)","03010(Ribosome);03010(Ribosome)","K02910","NA","ribosomal protein L31 [Source:HGNC Symbol;Acc:HGNC:10334]",{"v":26.3764928008979,"d":"26.38"},{"v":54.6686858312899,"d":"54.67"},{"v":0.482478998714126,"d":"0.48"},{"v":-1.05146194859035,"d":"-1.05"},{"v":0.0468894811603587,"d":"0.05"},{"v":0.514676318256376,"d":"0.51"},"down","yes"]
["ENSG00000130559","CAMSAP1","ENST00000389532;ENST00000468150;ENST00000460094;ENST00000312405;ENST00000493088;ENST00000482664;ENST00000487868;ENST00000492174","GO:0005737(cytoplasm);GO:0005856(cytoskeleton);GO:0031175(neuron projection development);GO:0008017(microtubule binding);GO:0005874(microtubule);GO:0005516(calmodulin binding);GO:0007010(cytoskeleton organization);GO:0022604(regulation of cell morphogenesis);GO:0030507(spectrin binding);GO:0030507(spectrin binding)","NA","NA","NA","calmodulin regulated spectrin associated protein 1 [Source:HGNC Symbol;Acc:HGNC:19946]",{"v":2.30549887097894,"d":"2.31"},{"v":0.75911396459153,"d":"0.76"},{"v":3.03709189728778,"d":"3.04"},{"v":1.60269056268895,"d":"1.60"},{"v":0.0469503990482512,"d":"0.05"},{"v":0.514694445349089,"d":"0.51"},"up","yes"]
["ENSG00000107614","TRDMT1","ENST00000354631;ENST00000424636;ENST00000495022;ENST00000377799;ENST00000313936;ENST00000452380;ENST00000486947;ENST00000488990","GO:0008168(methyltransferase activity);GO:0016740(transferase activity);GO:0032259(methylation);GO:0003723(RNA binding);GO:0005634(nucleus);GO:0008033(tRNA processing);GO:0005654(nucleoplasm);GO:0006400(tRNA modification);GO:0005737(cytoplasm);GO:0008175(tRNA methyltransferase activity);GO:0016428(tRNA (cytosine-5-)-methyltransferase activity);GO:0001975(response to amphetamine);GO:0030488(tRNA methylation);GO:0030488(tRNA methylation)","NA","NA","NA","tRNA aspartic acid methyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:2977]",{"v":0.188428721784528,"d":"0.19"},{"v":0.407427330232558,"d":"0.41"},{"v":0.462484246397937,"d":"0.46"},{"v":-1.11252387094631,"d":"-1.11"},{"v":0.0470037880055466,"d":"0.05"},{"v":0.514694445349089,"d":"0.51"},"down","yes"]
["MSTRG.7521","RPL17;RPL17-C18orf32;C18orf32","ENST00000578532;MSTRG.7521.11;ENST00000617346;ENST00000580387;ENST00000584895;ENST00000579248;ENST00000581091;ENST00000584364;ENST00000580261;ENST00000578528;ENST00000580210;ENST00000583036;ENST00000318240;ENST00000613385;ENST00000332968;ENST00000618619;MSTRG.7521.8;ENST00000582588;MSTRG.7521.6;ENST00000577910;ENST00000582935;MSTRG.7521.9;ENST00000582392;ENST00000618613;ENST00000579408;ENST00000581373;ENST00000583637;ENST00000582782;ENST00000581305;ENST00000615479;ENST00000615760;ENST00000579495;ENST00000581741","GO:0003723(RNA binding);GO:0005634(nucleus);GO:0006412(translation);GO:0030529(intracellular ribonucleoprotein complex);GO:0005622(intracellular);GO:0003735(structural constituent of ribosome);GO:0005840(ribosome);GO:0015934(large ribosomal subunit);GO:0005829(cytosol);GO:0005515(protein binding);GO:0006413(translational initiation);GO:0006364(rRNA processing);GO:0000184(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay);GO:0019083(viral transcription);GO:0006614(SRP-dependent cotranslational protein targeting to membrane);GO:0022625(cytosolic large ribosomal subunit);GO:0004871(signal transducer activity);GO:0007165(signal transduction);GO:0043123(positive regulation of I-kappaB kinase/NF-kappaB signaling);GO:0022625(cytosolic large ribosomal subunit)","03010(Ribosome);03010(Ribosome)","K02880","NA","ribosomal protein L17 [Source:HGNC Symbol;Acc:HGNC:10307];RPL17-C18orf32 readthrough [Source:HGNC Symbol;Acc:HGNC:44661];chromosome 18 open reading frame 32 [Source:HGNC Symbol;Acc:HGNC:31690]",{"v":35.3099560298652,"d":"35.31"},{"v":73.1457150299866,"d":"73.15"},{"v":0.482734443369507,"d":"0.48"},{"v":-1.05069832734332,"d":"-1.05"},{"v":0.0470240942491504,"d":"0.05"},{"v":0.514694445349089,"d":"0.51"},"down","yes"]
["MSTRG.4098","IRS2","ENST00000375856","GO:0008284(positive regulation of cell proliferation);GO:0046326(positive regulation of glucose import);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0043547(positive regulation of GTPase activity);GO:0005515(protein binding);GO:0004871(signal transducer activity);GO:0007165(signal transduction);GO:0005158(insulin receptor binding);GO:0036092(phosphatidylinositol-3-phosphate biosynthetic process);GO:0005886(plasma membrane);GO:0046854(phosphatidylinositol phosphorylation);GO:0000165(MAPK cascade);GO:0008286(insulin receptor signaling pathway);GO:0032024(positive regulation of insulin secretion);GO:0046934(phosphatidylinositol-4,5-bisphosphate 3-kinase activity);GO:0007411(axon guidance);GO:0014066(regulation of phosphatidylinositol 3-kinase signaling);GO:0038111(interleukin-7-mediated signaling pathway);GO:0048015(phosphatidylinositol-mediated signaling);GO:0005088(Ras guanyl-nucleotide exchange factor activity);GO:0016303(1-phosphatidylinositol-3-kinase activity);GO:0043548(phosphatidylinositol 3-kinase binding);GO:0032869(cellular response to insulin stimulus);GO:0045725(positive regulation of glycogen biosynthetic process);GO:0009749(response to glucose);GO:0030890(positive regulation of B cell proliferation);GO:0055088(lipid homeostasis);GO:0010748(negative regulation of plasma membrane long-chain fatty acid transport);GO:0006006(glucose metabolic process);GO:0010907(positive regulation of glucose metabolic process);GO:0032000(positive regulation of fatty acid beta-oxidation);GO:0019216(regulation of lipid metabolic process);GO:0019901(protein kinase binding);GO:0019903(protein phosphatase binding);GO:0019904(protein domain specific binding);GO:0071889(14-3-3 protein binding);GO:0002053(positive regulation of mesenchymal cell proliferation);GO:0002903(negative regulation of B cell apoptotic process);GO:0007420(brain development);GO:0008283(cell proliferation);GO:0030335(positive regulation of cell migration);GO:0030879(mammary gland development);GO:0033673(negative regulation of kinase activity);GO:0071333(cellular response to glucose stimulus);GO:1901653(cellular response to peptide);GO:0043234(protein complex)","04068(FoxO signaling pathway);04022(cGMP - PKG signaling pathway);04152(AMPK signaling pathway);04140(Autophagy - animal);04910(Insulin signaling pathway);04923(Regulation of lipolysis in adipocyte);04920(Adipocytokine signaling pathway);04211(Longevity regulating pathway - mammal);04213(Longevity regulating pathway - multiple species);05206(MicroRNAs in cancer);04930(Type II diabetes mellitus);04932(Non-alcoholic fatty liver disease (NAFLD));04931(Insulin resistance)","K07187","NA","insulin receptor substrate 2 [Source:HGNC Symbol;Acc:HGNC:6126]",{"v":5.845656,"d":"5.85"},{"v":1.938782,"d":"1.94"},{"v":3.01511773886904,"d":"3.02"},{"v":1.59221433975917,"d":"1.59"},{"v":0.0471055820955924,"d":"0.05"},{"v":0.515100870881463,"d":"0.52"},"up","yes"]
["MSTRG.12614","MGAT1","ENST00000307826;ENST00000427865;ENST00000513431;ENST00000510341;ENST00000514760;ENST00000505682;ENST00000504385;ENST00000504671;ENST00000512695;ENST00000506708;ENST00000506889;ENST00000514438;ENST00000508702;ENST00000506033;ENST00000502678;ENST00000333055;ENST00000512080;ENST00000506269;ENST00000446023;ENST00000514283;ENST00000508090;ENST00000393340;ENST00000513149","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0046872(metal ion binding);GO:0016740(transferase activity);GO:0016757(transferase activity, transferring glycosyl groups);GO:0006486(protein glycosylation);GO:0005794(Golgi apparatus);GO:0000139(Golgi membrane);GO:0008375(acetylglucosaminyltransferase activity);GO:0070062(extracellular exosome);GO:0005975(carbohydrate metabolic process);GO:1903561(extracellular vesicle);GO:0003827(alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity);GO:0001701(in utero embryonic development);GO:0006049(UDP-N-acetylglucosamine catabolic process);GO:0006049(UDP-N-acetylglucosamine catabolic process)","00510(N-Glycan biosynthesis);00510(N-Glycan biosynthesis)","K00726","EC:2.4.1.101","mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase [Source:HGNC Symbol;Acc:HGNC:7044]",{"v":2.75683827531099,"d":"2.76"},{"v":0.910077949550795,"d":"0.91"},{"v":3.0292331296146,"d":"3.03"},{"v":1.59895261213671,"d":"1.60"},{"v":0.0471862542788947,"d":"0.05"},{"v":0.515497620828602,"d":"0.52"},"up","yes"]
["MSTRG.1204","GAS5","ENST00000451607;ENST00000448718;ENST00000412059;ENST00000450589;ENST00000454068;ENST00000449589;MSTRG.1204.1;ENST00000416952;ENST00000456293;ENST00000456812;ENST00000452197;ENST00000449289;ENST00000454813;ENST00000414075;ENST00000432536;ENST00000422183;ENST00000430245;ENST00000425771;ENST00000455838;ENST00000422008;ENST00000436656;ENST00000458220;ENST00000421068;ENST00000431268;ENST00000443799;ENST00000436285;ENST00000422207;ENST00000444470;ENST00000442067","NA","NA","NA","NA","growth arrest specific 5 (non-protein coding) [Source:HGNC Symbol;Acc:HGNC:16355]",{"v":10.5532313536153,"d":"10.55"},{"v":21.9274781443383,"d":"21.93"},{"v":0.481278844933664,"d":"0.48"},{"v":-1.05505508521445,"d":"-1.06"},{"v":0.047253494632701,"d":"0.05"},{"v":0.515747023655598,"d":"0.52"},"down","yes"]
["ENSG00000160256","FAM207A","ENST00000291634;ENST00000479127;ENST00000458015;ENST00000485207;ENST00000397826","GO:0005515(protein binding);GO:0005515(protein binding)","NA","NA","NA","family with sequence similarity 207 member A [Source:HGNC Symbol;Acc:HGNC:15811]",{"v":1.22242269543509,"d":"1.22"},{"v":2.65298675891583,"d":"2.65"},{"v":0.460772256524433,"d":"0.46"},{"v":-1.11787424134406,"d":"-1.12"},{"v":0.0474203709717446,"d":"0.05"},{"v":0.515900454123405,"d":"0.52"},"down","yes"]
["MSTRG.6546","IFT20","ENST00000395418;ENST00000588477;ENST00000357896;ENST00000585089;ENST00000577498;ENST00000585313;ENST00000583796;ENST00000580991;ENST00000322326;ENST00000580357;ENST00000578547;ENST00000578985;ENST00000582797","GO:0005737(cytoplasm);GO:0005794(Golgi apparatus);GO:0005856(cytoskeleton);GO:0042995(cell projection);GO:0005515(protein binding);GO:0035735(intraciliary transport involved in cilium assembly);GO:0060271(cilium assembly);GO:0005929(cilium);GO:0030992(intraciliary transport particle B);GO:0097542(ciliary tip);GO:0070062(extracellular exosome);GO:0030030(cell projection organization);GO:0005814(centriole);GO:1902017(regulation of cilium assembly);GO:0000139(Golgi membrane);GO:0017137(Rab GTPase binding);GO:0005813(centrosome);GO:0005801(cis-Golgi network);GO:2000785(regulation of autophagosome assembly);GO:0034067(protein localization to Golgi apparatus);GO:0031514(motile cilium);GO:0002046(opsin binding);GO:0001736(establishment of planar polarity);GO:0001822(kidney development);GO:0007224(smoothened signaling pathway);GO:0008542(visual learning);GO:0022008(neurogenesis);GO:0035845(photoreceptor cell outer segment organization);GO:0036372(opsin transport);GO:0042073(intraciliary transport);GO:0051642(centrosome localization);GO:0055007(cardiac muscle cell differentiation);GO:0060122(inner ear receptor stereocilium organization);GO:0060828(regulation of canonical Wnt signaling pathway);GO:0061351(neural precursor cell proliferation);GO:0061512(protein localization to cilium);GO:0090002(establishment of protein localization to plasma membrane);GO:0090102(cochlea development);GO:0001750(photoreceptor outer segment);GO:0005902(microvillus);GO:0032391(photoreceptor connecting cilium);GO:0032420(stereocilium);GO:0036064(ciliary basal body);GO:0044292(dendrite terminus);GO:0097546(ciliary base);GO:1902636(kinociliary basal body);GO:1902636(kinociliary basal body)","NA","NA","NA","intraflagellar transport 20 [Source:HGNC Symbol;Acc:HGNC:30989]",{"v":1.73561680787109,"d":"1.74"},{"v":3.65108056585064,"d":"3.65"},{"v":0.475370722877138,"d":"0.48"},{"v":-1.0728750415452,"d":"-1.07"},{"v":0.0474398448247262,"d":"0.05"},{"v":0.515900454123405,"d":"0.52"},"down","yes"]
["ENSG00000116138","DNAJC16","ENST00000375847;ENST00000616884;ENST00000490811;ENST00000479655;ENST00000375838;ENST00000375849;ENST00000483270","GO:0005623(cell);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0045454(cell redox homeostasis);GO:0005829(cytosol);GO:0005829(cytosol)","NA","NA","NA","DnaJ heat shock protein family (Hsp40) member C16 [Source:HGNC Symbol;Acc:HGNC:29157]",{"v":1.20087337627,"d":"1.20"},{"v":0.392935225388299,"d":"0.39"},{"v":3.05616116519789,"d":"3.06"},{"v":1.61172062521298,"d":"1.61"},{"v":0.0474443779105925,"d":"0.05"},{"v":0.515900454123405,"d":"0.52"},"up","yes"]
["ENSG00000075151","EIF4G3","ENST00000400422;ENST00000634879;ENST00000264211;ENST00000374935;ENST00000476088;ENST00000374933;ENST00000438975;ENST00000356916;ENST00000411888;ENST00000602326;ENST00000634778;ENST00000435383","GO:0003723(RNA binding);GO:0003743(translation initiation factor activity);GO:0006412(translation);GO:0006413(translational initiation);GO:0005829(cytosol);GO:0006417(regulation of translation);GO:0016032(viral process);GO:0008135(translation factor activity, RNA binding);GO:0000339(RNA cap binding);GO:0006446(regulation of translational initiation);GO:0016281(eukaryotic translation initiation factor 4F complex);GO:0016281(eukaryotic translation initiation factor 4F complex)","03013(RNA transport);05416(Viral myocarditis);05416(Viral myocarditis)","K03260","NA","eukaryotic translation initiation factor 4 gamma 3 [Source:HGNC Symbol;Acc:HGNC:3298]",{"v":4.33472504324719,"d":"4.33"},{"v":1.4347185712797,"d":"1.43"},{"v":3.02130684722428,"d":"3.02"},{"v":1.59517271319135,"d":"1.60"},{"v":0.0475086595290987,"d":"0.05"},{"v":0.515900454123405,"d":"0.52"},"up","yes"]
["MSTRG.8410","RPS9","ENST00000391751;ENST00000436445;ENST00000302907;ENST00000495002;ENST00000626547;ENST00000484121;ENST00000391752;ENST00000460761;ENST00000445961;ENST00000402367;ENST00000391753;ENST00000448962;ENST00000441429","GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0006412(translation);GO:0030529(intracellular ribonucleoprotein complex);GO:0005622(intracellular);GO:0003735(structural constituent of ribosome);GO:0005840(ribosome);GO:0015935(small ribosomal subunit);GO:0005515(protein binding);GO:0022627(cytosolic small ribosomal subunit);GO:0019843(rRNA binding);GO:0005730(nucleolus);GO:0005925(focal adhesion);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0008284(positive regulation of cell proliferation);GO:0006413(translational initiation);GO:0006364(rRNA processing);GO:0000184(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay);GO:0019083(viral transcription);GO:0006614(SRP-dependent cotranslational protein targeting to membrane);GO:0045182(translation regulator activity);GO:0045903(positive regulation of translational fidelity);GO:0045903(positive regulation of translational fidelity)","03010(Ribosome);03010(Ribosome)","K02997","NA","ribosomal protein S9 [Source:HGNC Symbol;Acc:HGNC:10442]",{"v":82.0520025483871,"d":"82.05"},{"v":169.551869126516,"d":"169.55"},{"v":0.483934520870198,"d":"0.48"},{"v":-1.04711623913643,"d":"-1.05"},{"v":0.0475277301254172,"d":"0.05"},{"v":0.515900454123405,"d":"0.52"},"down","yes"]
["MSTRG.5642","CARHSP1","ENST00000311052;ENST00000563815;ENST00000562843;ENST00000565287;ENST00000569398;ENST00000396593;ENST00000569572;ENST00000611932;ENST00000619881;ENST00000610831;ENST00000614449;ENST00000567626","GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0005737(cytoplasm);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0005829(cytosol);GO:0005515(protein binding);GO:0000932(P-body);GO:0070062(extracellular exosome);GO:0019902(phosphatase binding);GO:0000177(cytoplasmic exosome (RNase complex));GO:0003730(mRNA 3'-UTR binding);GO:0035556(intracellular signal transduction);GO:0043488(regulation of mRNA stability);GO:0043186(P granule);GO:0043186(P granule)","NA","NA","NA","calcium regulated heat stable protein 1 [Source:HGNC Symbol;Acc:HGNC:17150]",{"v":1.71519053362023,"d":"1.72"},{"v":3.55924254993724,"d":"3.56"},{"v":0.481897625563752,"d":"0.48"},{"v":-1.05320140232957,"d":"-1.05"},{"v":0.0475778597269457,"d":"0.05"},{"v":0.515900454123405,"d":"0.52"},"down","yes"]
["MSTRG.7803","PDE4A","ENST00000293683;ENST00000592685;ENST00000586275;ENST00000440014;ENST00000590407;ENST00000380702;ENST00000589073","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0046872(metal ion binding);GO:0005654(nucleoplasm);GO:0016787(hydrolase activity);GO:0007165(signal transduction);GO:0005886(plasma membrane);GO:0042995(cell projection);GO:0048471(perinuclear region of cytoplasm);GO:0008081(phosphoric diester hydrolase activity);GO:0004114(3',5'-cyclic-nucleotide phosphodiesterase activity);GO:0005515(protein binding);GO:0005829(cytosol);GO:0032587(ruffle membrane);GO:0004115(3',5'-cyclic-AMP phosphodiesterase activity);GO:0006198(cAMP catabolic process);GO:0030552(cAMP binding);GO:0007608(sensory perception of smell);GO:0010738(regulation of protein kinase A signaling);GO:0035690(cellular response to drug);GO:0043949(regulation of cAMP-mediated signaling);GO:0043949(regulation of cAMP-mediated signaling)","00230(Purine metabolism);04024(cAMP signaling pathway);05032(Morphine addiction);05032(Morphine addiction)","K13293","EC:3.1.4.53","phosphodiesterase 4A [Source:HGNC Symbol;Acc:HGNC:8780]",{"v":0.783982449443274,"d":"0.78"},{"v":0.253573051760457,"d":"0.25"},{"v":3.09174198125706,"d":"3.09"},{"v":1.62841992537756,"d":"1.63"},{"v":0.0476246299038831,"d":"0.05"},{"v":0.515900454123405,"d":"0.52"},"up","yes"]
["MSTRG.6464","LRRC75A-AS1","MSTRG.6464.7;ENST00000481027;ENST00000475953;ENST00000480811;ENST00000481898;ENST00000580180;MSTRG.6464.2;ENST00000460249;ENST00000478103;ENST00000581361;ENST00000581718;ENST00000584177;ENST00000487066;ENST00000484836;ENST00000581913;ENST00000584926;ENST00000491009;ENST00000579473;ENST00000584141;ENST00000472367;ENST00000497774;ENST00000483140;ENST00000578757;ENST00000582911;ENST00000477249;ENST00000475947;ENST00000483588;ENST00000470491","NA","NA","NA","NA","LRRC75A antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:28619]",{"v":8.50340332987497,"d":"8.50"},{"v":17.6313015823357,"d":"17.63"},{"v":0.482290163897729,"d":"0.48"},{"v":-1.0520267076378,"d":"-1.05"},{"v":0.0476270096265289,"d":"0.05"},{"v":0.515900454123405,"d":"0.52"},"down","yes"]
["MSTRG.139","PIK3CD","MSTRG.139.2;ENST00000377346;ENST00000484851;ENST00000479223;MSTRG.139.1;ENST00000536656;ENST00000543390;ENST00000628140;ENST00000481137;ENST00000361110","GO:0005622(intracellular);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0046854(phosphatidylinositol phosphorylation);GO:0048015(phosphatidylinositol-mediated signaling);GO:0005737(cytoplasm);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0005515(protein binding);GO:0007165(signal transduction);GO:0030154(cell differentiation);GO:0036092(phosphatidylinositol-3-phosphate biosynthetic process);GO:0002376(immune system process);GO:0045087(innate immune response);GO:0006935(chemotaxis);GO:0006954(inflammatory response);GO:0002250(adaptive immune response);GO:0005886(plasma membrane);GO:0042629(mast cell granule);GO:0006468(protein phosphorylation);GO:0001816(cytokine production);GO:0030593(neutrophil chemotaxis);GO:0005829(cytosol);GO:0042113(B cell activation);GO:0005942(phosphatidylinositol 3-kinase complex);GO:0016303(1-phosphatidylinositol-3-kinase activity);GO:0035004(phosphatidylinositol 3-kinase activity);GO:0035005(1-phosphatidylinositol-4-phosphate 3-kinase activity);GO:0046934(phosphatidylinositol-4,5-bisphosphate 3-kinase activity);GO:0001779(natural killer cell differentiation);GO:0002551(mast cell chemotaxis);GO:0002679(respiratory burst involved in defense response);GO:0006661(phosphatidylinositol biosynthetic process);GO:0007411(axon guidance);GO:0010628(positive regulation of gene expression);GO:0010818(T cell chemotaxis);GO:0014065(phosphatidylinositol 3-kinase signaling);GO:0014066(regulation of phosphatidylinositol 3-kinase signaling);GO:0030101(natural killer cell activation);GO:0030168(platelet activation);GO:0030217(T cell differentiation);GO:0030335(positive regulation of cell migration);GO:0033031(positive regulation of neutrophil apoptotic process);GO:0035747(natural killer cell chemotaxis);GO:0035754(B cell chemotaxis);GO:0038111(interleukin-7-mediated signaling pathway);GO:0042110(T cell activation);GO:0043303(mast cell degranulation);GO:0050852(T cell receptor signaling pathway);GO:0050853(B cell receptor signaling pathway);GO:0060374(mast cell differentiation);GO:0072672(neutrophil extravasation);GO:0072672(neutrophil extravasation)","00562(Inositol phosphate metabolism);04014(Ras signaling pathway);04015(Rap1 signaling pathway);04012(ErbB signaling pathway);04370(VEGF signaling pathway);04630(Jak-STAT signaling pathway);04668(TNF signaling pathway);04066(HIF-1 signaling pathway);04068(FoxO signaling pathway);04070(Phosphatidylinositol signaling system);04072(Phospholipase D signaling pathway);04071(Sphingolipid signaling pathway);04024(cAMP signaling pathway);04151(PI3K-Akt signaling pathway);04152(AMPK signaling pathway);04150(mTOR signaling pathway);04140(Autophagy - animal);04210(Apoptosis);04218(Cellular senescence);04510(Focal adhesion);04550(Signaling pathways regulating pluripotency of stem cells);04810(Regulation of actin cytoskeleton);04611(Platelet activation);04620(Toll-like receptor signaling pathway);04650(Natural killer cell mediated cytotoxicity);04660(T cell receptor signaling pathway);04662(B cell receptor signaling pathway);04664(Fc epsilon RI signaling pathway);04666(Fc gamma R-mediated phagocytosis);04670(Leukocyte transendothelial migration);04062(Chemokine signaling pathway);04910(Insulin signaling pathway);04923(Regulation of lipolysis in adipocyte);04915(Estrogen signaling pathway);04914(Progesterone-mediated oocyte maturation);04917(Prolactin signaling pathway);04926(Relaxin signaling pathway);04919(Thyroid hormone signaling pathway);04973(Carbohydrate digestion and absorption);04960(Aldosterone-regulated sodium reabsorption);04725(Cholinergic synapse);04722(Neurotrophin signaling pathway);04750(Inflammatory mediator regulation of TRP channels);04360(Axon guidance);04380(Osteoclast differentiation);04211(Longevity regulating pathway - mammal);04213(Longevity regulating pathway - multiple species);05200(Pathways in cancer);05230(Central carbon metabolism in cancer);05231(Choline metabolism in cancer);05205(Proteoglycans in cancer);05203(Viral carcinogenesis);05210(Colorectal cancer);05212(Pancreatic cancer);05225(Hepatocellular carcinoma);05226(Gastric cancer);05214(Glioma);05221(Acute myeloid leukemia);05220(Chronic myeloid leukemia);05218(Melanoma);05211(Renal cell carcinoma);05215(Prostate cancer);05213(Endometrial cancer);05224(Breast cancer);05222(Small cell lung cancer);05223(Non-small cell lung cancer);05418(Fluid shear stress and atherosclerosis);04930(Type II diabetes mellitus);04932(Non-alcoholic fatty liver disease (NAFLD));04931(Insulin resistance);04933(AGE-RAGE signaling pathway in diabetic complications);05100(Bacterial invasion of epithelial cells);05166(HTLV-I infection);05162(Measles);05164(Influenza A);05161(Hepatitis B);05160(Hepatitis C);05167(Kaposi's sarcoma-associated herpesvirus infection);05169(Epstein-Barr virus infection);05165(Human papillomavirus infection);05146(Amoebiasis);05142(Chagas disease (American trypanosomiasis));01521(EGFR tyrosine kinase inhibitor resistance);01524(Platinum drug resistance);01522(Endocrine resistance);01522(Endocrine resistance)","K00922","EC:2.7.1.153","phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta [Source:HGNC Symbol;Acc:HGNC:8977]",{"v":51.135965560251,"d":"51.14"},{"v":17.0409356192469,"d":"17.04"},{"v":3.00077218192735,"d":"3.00"},{"v":1.5853337939513,"d":"1.59"},{"v":0.0476935440926152,"d":"0.05"},{"v":0.515900454123405,"d":"0.52"},"up","yes"]
["ENSG00000100228","RAB36","ENST00000263116;ENST00000420895","GO:0006810(transport);GO:0016020(membrane);GO:0015031(protein transport);GO:0005525(GTP binding);GO:0000166(nucleotide binding);GO:0003924(GTPase activity);GO:0005794(Golgi apparatus);GO:0000139(Golgi membrane);GO:0000139(Golgi membrane)","NA","NA","NA","RAB36, member RAS oncogene family [Source:HGNC Symbol;Acc:HGNC:9775]",{"v":1.13439163574385,"d":"1.13"},{"v":0.365506239103969,"d":"0.37"},{"v":3.10361770711435,"d":"3.10"},{"v":1.63395086228767,"d":"1.63"},{"v":0.0477435173133012,"d":"0.05"},{"v":0.515900454123405,"d":"0.52"},"up","yes"]
["ENSG00000105426","PTPRS","ENST00000587303;ENST00000589851;ENST00000588012;ENST00000592099;ENST00000591760","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016787(hydrolase activity);GO:0007155(cell adhesion);GO:0004725(protein tyrosine phosphatase activity);GO:0016791(phosphatase activity);GO:0006470(protein dephosphorylation);GO:0016311(dephosphorylation);GO:0005886(plasma membrane);GO:0004721(phosphoprotein phosphatase activity);GO:0042995(cell projection);GO:0005515(protein binding);GO:0030054(cell junction);GO:0045202(synapse);GO:0045211(postsynaptic membrane);GO:0031410(cytoplasmic vesicle);GO:0008201(heparin binding);GO:0030424(axon);GO:0043204(perikaryon);GO:0070062(extracellular exosome);GO:0035335(peptidyl-tyrosine dephosphorylation);GO:0014069(postsynaptic density);GO:0005887(integral component of plasma membrane);GO:0043005(neuron projection);GO:0030672(synaptic vesicle membrane);GO:0035374(chondroitin sulfate binding);GO:0043395(heparan sulfate proteoglycan binding);GO:0010977(negative regulation of neuron projection development);GO:0048681(negative regulation of axon regeneration);GO:0032688(negative regulation of interferon-beta production);GO:0030285(integral component of synaptic vesicle membrane);GO:0061000(negative regulation of dendritic spine development);GO:0030517(negative regulation of axon extension);GO:0021510(spinal cord development);GO:0021549(cerebellum development);GO:0021766(hippocampus development);GO:0021987(cerebral cortex development);GO:0022038(corpus callosum development);GO:0032687(negative regulation of interferon-alpha production);GO:0034164(negative regulation of toll-like receptor 9 signaling pathway);GO:0048671(negative regulation of collateral sprouting);GO:0090557(establishment of endothelial intestinal barrier);GO:0099061(integral component of postsynaptic density membrane);GO:0099061(integral component of postsynaptic density membrane)","NA","NA","NA","protein tyrosine phosphatase, receptor type S [Source:HGNC Symbol;Acc:HGNC:9681]",{"v":0.358286460245184,"d":"0.36"},{"v":0.112894641681261,"d":"0.11"},{"v":3.17363565630285,"d":"3.17"},{"v":1.66613651159581,"d":"1.67"},{"v":0.0477562204583364,"d":"0.05"},{"v":0.515900454123405,"d":"0.52"},"up","yes"]
["ENSG00000233968","AL157895.1","ENST00000451713;ENST00000431157;ENST00000423551","NA","NA","NA","NA",null,{"v":0.497195782426778,"d":"0.50"},{"v":1.07383425941423,"d":"1.07"},{"v":0.463009796966242,"d":"0.46"},{"v":-1.11088537465222,"d":"-1.11"},{"v":0.0478579012604845,"d":"0.05"},{"v":0.516178884146486,"d":"0.52"},"down","yes"]
["MSTRG.2971","TIRAP","ENST00000392679;ENST00000392678;ENST00000392680;ENST00000462401;ENST00000467006;ENST00000479770;ENST00000488598","GO:0070374(positive regulation of ERK1 and ERK2 cascade);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0007165(signal transduction);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0002376(immune system process);GO:0045087(innate immune response);GO:0006954(inflammatory response);GO:0005829(cytosol);GO:0042803(protein homodimerization activity);GO:0046982(protein heterodimerization activity);GO:0002755(MyD88-dependent toll-like receptor signaling pathway);GO:0032496(response to lipopolysaccharide);GO:0032735(positive regulation of interleukin-12 production);GO:0032757(positive regulation of interleukin-8 production);GO:0032760(positive regulation of tumor necrosis factor production);GO:0034142(toll-like receptor 4 signaling pathway);GO:0051092(positive regulation of NF-kappaB transcription factor activity);GO:0046330(positive regulation of JNK cascade);GO:0043123(positive regulation of I-kappaB kinase/NF-kappaB signaling);GO:0090023(positive regulation of neutrophil chemotaxis);GO:0030674(protein binding, bridging);GO:0007166(cell surface receptor signaling pathway);GO:0071221(cellular response to bacterial lipopeptide);GO:0032587(ruffle membrane);GO:0030139(endocytic vesicle);GO:2000343(positive regulation of chemokine (C-X-C motif) ligand 2 production);GO:0050830(defense response to Gram-positive bacterium);GO:0030890(positive regulation of B cell proliferation);GO:0005080(protein kinase C binding);GO:0070935(3'-UTR-mediated mRNA stabilization);GO:0034145(positive regulation of toll-like receptor 4 signaling pathway);GO:0005546(phosphatidylinositol-4,5-bisphosphate binding);GO:0035662(Toll-like receptor 4 binding);GO:0035663(Toll-like receptor 2 binding);GO:0007250(activation of NF-kappaB-inducing kinase activity);GO:0030099(myeloid cell differentiation);GO:0032648(regulation of interferon-beta production);GO:0032738(positive regulation of interleukin-15 production);GO:0034137(positive regulation of toll-like receptor 2 signaling pathway);GO:0034141(positive regulation of toll-like receptor 3 signaling pathway);GO:0035665(TIRAP-dependent toll-like receptor 4 signaling pathway);GO:0044130(negative regulation of growth of symbiont in host);GO:0045088(regulation of innate immune response);GO:0045410(positive regulation of interleukin-6 biosynthetic process);GO:0071223(cellular response to lipoteichoic acid);GO:0090073(positive regulation of protein homodimerization activity);GO:2000340(positive regulation of chemokine (C-X-C motif) ligand 1 production);GO:2000340(positive regulation of chemokine (C-X-C motif) ligand 1 production)","04064(NF-kappa B signaling pathway);04620(Toll-like receptor signaling pathway);05133(Pertussis);05152(Tuberculosis);05161(Hepatitis B);05161(Hepatitis B)","K05403","NA","TIR domain containing adaptor protein [Source:HGNC Symbol;Acc:HGNC:17192]",{"v":2.98747555165692,"d":"2.99"},{"v":0.974871683375104,"d":"0.97"},{"v":3.06448079537399,"d":"3.06"},{"v":1.61564266367449,"d":"1.62"},{"v":0.0478708910897929,"d":"0.05"},{"v":0.516178884146486,"d":"0.52"},"up","yes"]
["ENSG00000123562","MORF4L2","ENST00000360458;ENST00000418819;ENST00000442614;ENST00000498064;ENST00000434230;ENST00000474653;ENST00000451301;ENST00000488331;ENST00000422355;ENST00000467755;ENST00000422154;ENST00000441076;ENST00000433176;ENST00000492116","GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0016569(covalent chromatin modification);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0006281(DNA repair);GO:0006974(cellular response to DNA damage stimulus);GO:0006325(chromatin organization);GO:0005730(nucleolus);GO:0040008(regulation of growth);GO:0006338(chromatin remodeling);GO:0006342(chromatin silencing);GO:0016575(histone deacetylation);GO:0043967(histone H4 acetylation);GO:0043968(histone H2A acetylation);GO:0035267(NuA4 histone acetyltransferase complex);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0051155(positive regulation of striated muscle cell differentiation);GO:0051155(positive regulation of striated muscle cell differentiation)","NA","NA","NA","mortality factor 4 like 2 [Source:HGNC Symbol;Acc:HGNC:16849]",{"v":2.84559332590634,"d":"2.85"},{"v":5.91510565747734,"d":"5.92"},{"v":0.481072273376757,"d":"0.48"},{"v":-1.05567444286811,"d":"-1.06"},{"v":0.047928305856707,"d":"0.05"},{"v":0.516318567638162,"d":"0.52"},"down","yes"]
["MSTRG.14920","ORM1","ENST00000259396;ENST00000477456","GO:0006810(transport);GO:0005615(extracellular space);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0070062(extracellular exosome);GO:0072562(blood microparticle);GO:0043312(neutrophil degranulation);GO:0006953(acute-phase response);GO:0006954(inflammatory response);GO:0050718(positive regulation of interleukin-1 beta secretion);GO:1904469(positive regulation of tumor necrosis factor secretion);GO:0002576(platelet degranulation);GO:0031093(platelet alpha granule lumen);GO:0035580(specific granule lumen);GO:1904724(tertiary granule lumen);GO:0050716(positive regulation of interleukin-1 secretion);GO:0002682(regulation of immune system process);GO:0032715(negative regulation of interleukin-6 production);GO:0032720(negative regulation of tumor necrosis factor production);GO:0032720(negative regulation of tumor necrosis factor production)","NA","NA","NA","orosomucoid 1 [Source:HGNC Symbol;Acc:HGNC:8498]",{"v":8.09565770699223,"d":"8.10"},{"v":16.776165982242,"d":"16.78"},{"v":0.482569003880964,"d":"0.48"},{"v":-1.05119284278861,"d":"-1.05"},{"v":0.0480754424096167,"d":"0.05"},{"v":0.517423644766338,"d":"0.52"},"down","yes"]
["MSTRG.9228","TLK1","ENST00000359766;ENST00000431350;ENST00000413010;ENST00000470340;ENST00000478683;ENST00000409443;ENST00000466220;ENST00000360843;ENST00000486857","GO:0005634(nucleus);GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0016569(covalent chromatin modification);GO:0005515(protein binding);GO:0006974(cellular response to DNA damage stimulus);GO:0007049(cell cycle);GO:0006886(intracellular protein transport);GO:0035556(intracellular signal transduction);GO:0001672(regulation of chromatin assembly or disassembly);GO:0001672(regulation of chromatin assembly or disassembly)","NA","NA","NA","tousled like kinase 1 [Source:HGNC Symbol;Acc:HGNC:11841]",{"v":6.03503195800106,"d":"6.04"},{"v":2.01000895215311,"d":"2.01"},{"v":3.00249008917914,"d":"3.00"},{"v":1.58615948379412,"d":"1.59"},{"v":0.0482026382425345,"d":"0.05"},{"v":0.518224047128752,"d":"0.52"},"up","yes"]
["ENSG00000154309","DISP1","ENST00000284476;ENST00000482856;ENST00000360254","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005515(protein binding);GO:0007275(multicellular organism development);GO:0007224(smoothened signaling pathway);GO:0016323(basolateral plasma membrane);GO:0015833(peptide transport);GO:0060539(diaphragm development);GO:0050708(regulation of protein secretion);GO:0070207(protein homotrimerization);GO:0015197(peptide transporter activity);GO:0007225(patched ligand maturation);GO:0007368(determination of left/right symmetry);GO:0007389(pattern specification process);GO:0009880(embryonic pattern specification);GO:0009953(dorsal/ventral pattern formation);GO:0009953(dorsal/ventral pattern formation)","NA","NA","NA","dispatched RND transporter family member 1 [Source:HGNC Symbol;Acc:HGNC:19711]",{"v":0.590325337049424,"d":"0.59"},{"v":0.188492746191007,"d":"0.19"},{"v":3.1318199186892,"d":"3.13"},{"v":1.6470012592818,"d":"1.65"},{"v":0.0482390592393164,"d":"0.05"},{"v":0.518224047128752,"d":"0.52"},"up","yes"]
["MSTRG.7711","RPL36;HSD11B1L","ENST00000579446;ENST00000579649;ENST00000394580;ENST00000347512;ENST00000581423;ENST00000422535;ENST00000582463;ENST00000411793;ENST00000578167;ENST00000339423;ENST00000581773;ENST00000590786;ENST00000342970;ENST00000584904;ENST00000577920;ENST00000581893;ENST00000581521","GO:0003723(RNA binding);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0006412(translation);GO:0030529(intracellular ribonucleoprotein complex);GO:0005622(intracellular);GO:0003735(structural constituent of ribosome);GO:0005840(ribosome);GO:0005730(nucleolus);GO:0005829(cytosol);GO:0002181(cytoplasmic translation);GO:0006413(translational initiation);GO:0006364(rRNA processing);GO:0000184(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay);GO:0019083(viral transcription);GO:0006614(SRP-dependent cotranslational protein targeting to membrane);GO:0022625(cytosolic large ribosomal subunit);GO:0043231(intracellular membrane-bounded organelle);GO:0005654(nucleoplasm);GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0005576(extracellular region);GO:0005576(extracellular region)","03010(Ribosome);03010(Ribosome)","K02920","NA","ribosomal protein L36 [Source:HGNC Symbol;Acc:HGNC:13631];hydroxysteroid 11-beta dehydrogenase 1 like [Source:HGNC Symbol;Acc:HGNC:30419]",{"v":20.7466571733498,"d":"20.75"},{"v":42.7462539362533,"d":"42.75"},{"v":0.485344451569696,"d":"0.49"},{"v":-1.04291909565006,"d":"-1.04"},{"v":0.0483668438491681,"d":"0.05"},{"v":0.519116596691672,"d":"0.52"},"down","yes"]
["MSTRG.11522","S100P","ENST00000296370","GO:0005737(cytoplasm);GO:0005634(nucleus);GO:0016020(membrane);GO:0046872(metal ion binding);GO:0005509(calcium ion binding);GO:0005886(plasma membrane);GO:0042995(cell projection);GO:0005515(protein binding);GO:0016604(nuclear body);GO:0005576(extracellular region);GO:0046914(transition metal ion binding);GO:0045296(cadherin binding);GO:0070062(extracellular exosome);GO:0043312(neutrophil degranulation);GO:0034774(secretory granule lumen);GO:0010033(response to organic substance);GO:0031528(microvillus membrane);GO:0043542(endothelial cell migration);GO:0050786(RAGE receptor binding);GO:0000287(magnesium ion binding);GO:0048306(calcium-dependent protein binding)","NA","NA","NA","S100 calcium binding protein P [Source:HGNC Symbol;Acc:HGNC:10504]",{"v":7.89610634375,"d":"7.90"},{"v":16.35171923125,"d":"16.35"},{"v":0.482891507130311,"d":"0.48"},{"v":-1.05022900459843,"d":"-1.05"},{"v":0.0484549239713891,"d":"0.05"},{"v":0.519197247367475,"d":"0.52"},"down","yes"]
["MSTRG.659","NEXN","ENST00000330010;ENST00000401035;ENST00000480732;ENST00000470735;ENST00000440324","GO:0005737(cytoplasm);GO:0003779(actin binding);GO:0005856(cytoskeleton);GO:0030054(cell junction);GO:0005925(focal adhesion);GO:0051015(actin filament binding);GO:0030018(Z disc);GO:0005912(adherens junction);GO:0030334(regulation of cell migration);GO:0008307(structural constituent of muscle);GO:0051493(regulation of cytoskeleton organization);GO:0048739(cardiac muscle fiber development);GO:0048739(cardiac muscle fiber development)","NA","NA","NA","nexilin F-actin binding protein [Source:HGNC Symbol;Acc:HGNC:29557]",{"v":1.85489966614067,"d":"1.85"},{"v":0.608210716185753,"d":"0.61"},{"v":3.04976485414993,"d":"3.05"},{"v":1.60869801092805,"d":"1.61"},{"v":0.0484637747478122,"d":"0.05"},{"v":0.519197247367475,"d":"0.52"},"up","yes"]
["MSTRG.3758","TPCN1","ENST00000550785;ENST00000541517;ENST00000546503;ENST00000547955;ENST00000552542;ENST00000335509;ENST00000551127;ENST00000552985;ENST00000548465;ENST00000550543;ENST00000551099;ENST00000546781;ENST00000546907;ENST00000552077;ENST00000551096;ENST00000546787","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0055085(transmembrane transport);GO:0005216(ion channel activity);GO:0006811(ion transport);GO:0034220(ion transmembrane transport);GO:0070588(calcium ion transmembrane transport);GO:0005245(voltage-gated calcium channel activity);GO:0006810(transport);GO:0005765(lysosomal membrane);GO:0005244(voltage-gated ion channel activity);GO:0034765(regulation of ion transmembrane transport);GO:0005515(protein binding);GO:0006816(calcium ion transport);GO:0005262(calcium channel activity);GO:0005764(lysosome);GO:0042802(identical protein binding);GO:0051209(release of sequestered calcium ion into cytosol);GO:0005886(plasma membrane);GO:0005768(endosome);GO:0010008(endosome membrane);GO:0086010(membrane depolarization during action potential);GO:0010508(positive regulation of autophagy);GO:0072345(NAADP-sensitive calcium-release channel activity);GO:0072345(NAADP-sensitive calcium-release channel activity)","NA","NA","NA","two pore segment channel 1 [Source:HGNC Symbol;Acc:HGNC:18182]",{"v":3.08807389436297,"d":"3.09"},{"v":1.02669090582035,"d":"1.03"},{"v":3.00779317013189,"d":"3.01"},{"v":1.58870536399553,"d":"1.59"},{"v":0.0485768152088258,"d":"0.05"},{"v":0.519928622138335,"d":"0.52"},"up","yes"]
["ENSG00000123595","RAB9A","ENST00000464506;ENST00000243325","GO:0006810(transport);GO:0016020(membrane);GO:0015031(protein transport);GO:0005525(GTP binding);GO:0000166(nucleotide binding);GO:0003924(GTPase activity);GO:0005794(Golgi apparatus);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0042470(melanosome);GO:0000139(Golgi membrane);GO:0030659(cytoplasmic vesicle membrane);GO:0031410(cytoplasmic vesicle);GO:0005768(endosome);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0030670(phagocytic vesicle membrane);GO:0061024(membrane organization);GO:0005770(late endosome);GO:0042147(retrograde transport, endosome to Golgi);GO:0032588(trans-Golgi network membrane);GO:0019003(GDP binding);GO:0045921(positive regulation of exocytosis);GO:0030133(transport vesicle);GO:0045335(phagocytic vesicle);GO:0005764(lysosome);GO:0052405(negative regulation by host of symbiont molecular function);GO:0032880(regulation of protein localization);GO:0032880(regulation of protein localization)","05162(Measles);05162(Measles)","K07899","NA","RAB9A, member RAS oncogene family [Source:HGNC Symbol;Acc:HGNC:9792]",{"v":1.12500155807365,"d":"1.13"},{"v":0.356671930594901,"d":"0.36"},{"v":3.15416342462732,"d":"3.15"},{"v":1.65725741148902,"d":"1.66"},{"v":0.0487139981558476,"d":"0.05"},{"v":0.52091681453394,"d":"0.52"},"up","yes"]
["MSTRG.3785","RPLP0","ENST00000551150;ENST00000549098;ENST00000551258;ENST00000392514;ENST00000546989;ENST00000313104;ENST00000228306;ENST00000547191;ENST00000548495;ENST00000548568;ENST00000546990;ENST00000547173;ENST00000547211;ENST00000551783;ENST00000548551;ENST00000552292;ENST00000546564;ENST00000552902;ENST00000551914;ENST00000549242;ENST00000551336;ENST00000547475;ENST00000551217;ENST00000550856;ENST00000550423;ENST00000552461","GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0006412(translation);GO:0005783(endoplasmic reticulum);GO:0005829(cytosol);GO:0030529(intracellular ribonucleoprotein complex);GO:0005622(intracellular);GO:0005840(ribosome);GO:0005515(protein binding);GO:0003735(structural constituent of ribosome);GO:0042254(ribosome biogenesis);GO:0005925(focal adhesion);GO:0070062(extracellular exosome);GO:0016032(viral process);GO:0022625(cytosolic large ribosomal subunit);GO:0035722(interleukin-12-mediated signaling pathway);GO:0006413(translational initiation);GO:0006364(rRNA processing);GO:0036464(cytoplasmic ribonucleoprotein granule);GO:0000184(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay);GO:0019083(viral transcription);GO:0006614(SRP-dependent cotranslational protein targeting to membrane);GO:0006614(SRP-dependent cotranslational protein targeting to membrane)","03010(Ribosome);03010(Ribosome)","K02941","NA","ribosomal protein lateral stalk subunit P0 [Source:HGNC Symbol;Acc:HGNC:10371]",{"v":97.0511044803799,"d":"97.05"},{"v":199.530877612597,"d":"199.53"},{"v":0.486396419649952,"d":"0.49"},{"v":-1.03979548570346,"d":"-1.04"},{"v":0.04878713050368,"d":"0.05"},{"v":0.521218902060015,"d":"0.52"},"down","yes"]
["MSTRG.10716","HMGB1P5","ENST00000451497;ENST00000255320","NA","NA","NA","NA","high mobility group box 1 pseudogene 5 [Source:HGNC Symbol;Acc:HGNC:4997]",{"v":3.35045581368137,"d":"3.35"},{"v":1.08314359135914,"d":"1.08"},{"v":3.09327021865788,"d":"3.09"},{"v":1.62913286837365,"d":"1.63"},{"v":0.0488980410397547,"d":"0.05"},{"v":0.521900503085014,"d":"0.52"},"up","yes"]
["ENSG00000185829","ARL17A","ENST00000336125;ENST00000329240;ENST00000622488;ENST00000570550;ENST00000445552;ENST00000573185","GO:0006810(transport);GO:0015031(protein transport);GO:0005525(GTP binding);GO:0007264(small GTPase mediated signal transduction);GO:0000166(nucleotide binding);GO:0005794(Golgi apparatus);GO:0005622(intracellular);GO:0016192(vesicle-mediated transport);GO:0016192(vesicle-mediated transport)","NA","NA","NA","ADP ribosylation factor like GTPase 17A [Source:HGNC Symbol;Acc:HGNC:24096]",{"v":0.697723859144118,"d":"0.70"},{"v":0.22154545384763,"d":"0.22"},{"v":3.14934857396796,"d":"3.15"},{"v":1.65505344566129,"d":"1.66"},{"v":0.0489408118366985,"d":"0.05"},{"v":0.521900503085014,"d":"0.52"},"up","yes"]
["ENSG00000267279","AC090409.1","ENST00000586949;ENST00000587754","NA","NA","NA","NA",null,{"v":1.13961314762302,"d":"1.14"},{"v":2.43145253461218,"d":"2.43"},{"v":0.468696440255532,"d":"0.47"},{"v":-1.09327425728227,"d":"-1.09"},{"v":0.0490312700208775,"d":"0.05"},{"v":0.522385448396744,"d":"0.52"},"down","yes"]
["MSTRG.14598","SLC45A4","MSTRG.14598.2;ENST00000517878;ENST00000519067;ENST00000024061;ENST00000521804;ENST00000520137;ENST00000519986","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0008506(sucrose:proton symporter activity);GO:0015770(sucrose transport);GO:0015770(sucrose transport)","NA","NA","NA","solute carrier family 45 member 4 [Source:HGNC Symbol;Acc:HGNC:29196]",{"v":10.5089930876289,"d":"10.51"},{"v":3.5178967093929,"d":"3.52"},{"v":2.98729438518463,"d":"2.99"},{"v":1.57883941612835,"d":"1.58"},{"v":0.0490937975813148,"d":"0.05"},{"v":0.522572201019073,"d":"0.52"},"up","yes"]
["ENSG00000103932","RPAP1","ENST00000304330;ENST00000565035;ENST00000561603;ENST00000564934;ENST00000562303;ENST00000565167;ENST00000561631;ENST00000569829;ENST00000567866","GO:0005634(nucleus);GO:0016740(transferase activity);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0016779(nucleotidyltransferase activity);GO:0003899(DNA-directed 5'-3' RNA polymerase activity);GO:0006366(transcription from RNA polymerase II promoter);GO:0006366(transcription from RNA polymerase II promoter)","NA","NA","NA","RNA polymerase II associated protein 1 [Source:HGNC Symbol;Acc:HGNC:24567]",{"v":1.76805195330684,"d":"1.77"},{"v":0.58418418464377,"d":"0.58"},{"v":3.02653169973265,"d":"3.03"},{"v":1.59766546183866,"d":"1.60"},{"v":0.049442091660337,"d":"0.05"},{"v":0.525659361748613,"d":"0.53"},"up","yes"]
["ENSG00000143190","POU2F1","ENST00000367866;ENST00000367865;ENST00000442313;ENST00000367862;ENST00000470928;ENST00000560232;ENST00000559038;ENST00000443275;ENST00000492850;ENST00000271411;ENST00000541643;ENST00000490100;ENST00000559648;ENST00000429375","GO:0005634(nucleus);GO:0043231(intracellular membrane-bounded organelle);GO:0005783(endoplasmic reticulum);GO:0005654(nucleoplasm);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0043565(sequence-specific DNA binding);GO:0005515(protein binding);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0045892(negative regulation of transcription, DNA-templated);GO:0042795(snRNA transcription from RNA polymerase II promoter);GO:0000979(RNA polymerase II core promoter sequence-specific DNA binding);GO:0000983(transcription factor activity, RNA polymerase II core promoter sequence-specific);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0090575(RNA polymerase II transcription factor complex);GO:0090575(RNA polymerase II transcription factor complex)","NA","NA","NA","POU class 2 homeobox 1 [Source:HGNC Symbol;Acc:HGNC:9212]",{"v":1.91014972227512,"d":"1.91"},{"v":0.638564784675935,"d":"0.64"},{"v":2.99131704114329,"d":"2.99"},{"v":1.58078082568475,"d":"1.58"},{"v":0.0494903478248906,"d":"0.05"},{"v":0.525659361748613,"d":"0.53"},"up","yes"]
["MSTRG.2059","AC136475.3","ENST00000533924;ENST00000534742;ENST00000525217","NA","NA","NA","NA",null,{"v":1.56274938953488,"d":"1.56"},{"v":3.34933400697674,"d":"3.35"},{"v":0.466585114019574,"d":"0.47"},{"v":-1.09978781472496,"d":"-1.10"},{"v":0.049539806345652,"d":"0.05"},{"v":0.525659361748613,"d":"0.53"},"down","yes"]
["MSTRG.12872","LY6G5C","ENST00000460141;ENST00000375863;ENST00000461572;ENST00000474395","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005576(extracellular region);GO:0042802(identical protein binding);GO:0051260(protein homooligomerization);GO:0009897(external side of plasma membrane);GO:0043234(protein complex);GO:0043234(protein complex)","NA","NA","NA","lymphocyte antigen 6 family member G5C [Source:HGNC Symbol;Acc:HGNC:13932]",{"v":0.306195101106448,"d":"0.31"},{"v":0.677290393361312,"d":"0.68"},{"v":0.452088356940718,"d":"0.45"},{"v":-1.14532333184269,"d":"-1.15"},{"v":0.0497030294087492,"d":"0.05"},{"v":0.525659361748613,"d":"0.53"},"down","yes"]
["MSTRG.9874","CABLES2","ENST00000279101","GO:0051301(cell division);GO:0007049(cell cycle);GO:0051726(regulation of cell cycle)","NA","NA","NA","Cdk5 and Abl enzyme substrate 2 [Source:HGNC Symbol;Acc:HGNC:16143]",{"v":1.298126,"d":"1.30"},{"v":0.422114,"d":"0.42"},{"v":3.07529719459672,"d":"3.08"},{"v":1.62072583824134,"d":"1.62"},{"v":0.0497254405609664,"d":"0.05"},{"v":0.525659361748613,"d":"0.53"},"up","yes"]
["MSTRG.12373","IGIP","ENST00000333305","GO:0005576(extracellular region)","NA","NA","NA","IgA inducing protein [Source:HGNC Symbol;Acc:HGNC:33847]",{"v":1.421339,"d":"1.42"},{"v":0.463346,"d":"0.46"},{"v":3.06755426830058,"d":"3.07"},{"v":1.61708886692504,"d":"1.62"},{"v":0.0497254405609664,"d":"0.05"},{"v":0.525659361748613,"d":"0.53"},"up","yes"]
["ENSG00000163584","RPL22L1","ENST00000494771;ENST00000475836;ENST00000295830;ENST00000463836","GO:0030529(intracellular ribonucleoprotein complex);GO:0005622(intracellular);GO:0003735(structural constituent of ribosome);GO:0006412(translation);GO:0005840(ribosome);GO:0003723(RNA binding);GO:0022625(cytosolic large ribosomal subunit);GO:0002181(cytoplasmic translation);GO:0002181(cytoplasmic translation)","03010(Ribosome);03010(Ribosome)","K02891","NA","ribosomal protein L22 like 1 [Source:HGNC Symbol;Acc:HGNC:27610]",{"v":1.09799803310404,"d":"1.10"},{"v":2.30389949570077,"d":"2.30"},{"v":0.476582435628367,"d":"0.48"},{"v":-1.06920231268103,"d":"-1.07"},{"v":0.0497495789275984,"d":"0.05"},{"v":0.525659361748613,"d":"0.53"},"down","yes"]
["ENSG00000134057","CCNB1","ENST00000256442;ENST00000503507;ENST00000513102;ENST00000507798","GO:0005737(cytoplasm);GO:0005634(nucleus);GO:0005829(cytosol);GO:0051301(cell division);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0007049(cell cycle);GO:0005813(centrosome);GO:0005815(microtubule organizing center);GO:0006977(DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest);GO:0005654(nucleoplasm);GO:0019901(protein kinase binding);GO:0031145(anaphase-promoting complex-dependent catabolic process);GO:0051437(positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition);GO:0000086(G2/M transition of mitotic cell cycle);GO:0051436(negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle);GO:0044389(ubiquitin-like protein ligase binding);GO:0042787(protein ubiquitination involved in ubiquitin-dependent protein catabolic process);GO:0051439(regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle);GO:0045931(positive regulation of mitotic cell cycle);GO:0000942(condensed nuclear chromosome outer kinetochore);GO:0007052(mitotic spindle organization);GO:0007077(mitotic nuclear envelope disassembly);GO:0004693(cyclin-dependent protein serine/threonine kinase activity);GO:0051726(regulation of cell cycle);GO:0005759(mitochondrial matrix);GO:1905448(positive regulation of mitochondrial ATP synthesis coupled electron transport);GO:0097125(cyclin B1-CDK1 complex);GO:0005113(patched binding);GO:0016301(kinase activity);GO:0035173(histone kinase activity);GO:0061575(cyclin-dependent protein serine/threonine kinase activator activity);GO:0000278(mitotic cell cycle);GO:0001556(oocyte maturation);GO:0001701(in utero embryonic development);GO:0001933(negative regulation of protein phosphorylation);GO:0006461(protein complex assembly);GO:0006468(protein phosphorylation);GO:0007080(mitotic metaphase plate congression);GO:0007283(spermatogenesis);GO:0009612(response to mechanical stimulus);GO:0009636(response to toxic substance);GO:0010629(negative regulation of gene expression);GO:0031442(positive regulation of mRNA 3'-end processing);GO:0031662(positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle);GO:0033129(positive regulation of histone phosphorylation);GO:0042246(tissue regeneration);GO:0042493(response to drug);GO:0045787(positive regulation of cell cycle);GO:0046680(response to DDT);GO:0048146(positive regulation of fibroblast proliferation);GO:0048565(digestive tract development);GO:0051987(positive regulation of attachment of spindle microtubules to kinetochore);GO:0055015(ventricular cardiac muscle cell development);GO:0060045(positive regulation of cardiac muscle cell proliferation);GO:0060623(regulation of chromosome condensation);GO:0071283(cellular response to iron(III) ion);GO:0071398(cellular response to fatty acid);GO:0071407(cellular response to organic cyclic compound);GO:0071456(cellular response to hypoxia);GO:0090266(regulation of mitotic cell cycle spindle assembly checkpoint);GO:2000775(histone H3-S10 phosphorylation involved in chromosome condensation);GO:0000922(spindle pole);GO:0016020(membrane);GO:0016020(membrane)","04068(FoxO signaling pathway);04110(Cell cycle);04114(Oocyte meiosis);04115(p53 signaling pathway);04218(Cellular senescence);04914(Progesterone-mediated oocyte maturation);04914(Progesterone-mediated oocyte maturation)","K05868","NA","cyclin B1 [Source:HGNC Symbol;Acc:HGNC:1579]",{"v":0.400088252541048,"d":"0.40"},{"v":0.860218652853792,"d":"0.86"},{"v":0.465100647624587,"d":"0.47"},{"v":-1.10438514615765,"d":"-1.10"},{"v":0.0497628975239512,"d":"0.05"},{"v":0.525659361748613,"d":"0.53"},"down","yes"]
["MSTRG.3430","BLOC1S1;RDH5;AC009779.3","ENST00000548925;ENST00000547301;ENST00000551926;ENST00000547072;ENST00000553160;ENST00000547076;ENST00000257895;ENST00000550412;ENST00000550608;ENST00000553100;ENST00000548082;ENST00000548556;ENST00000551946;ENST00000549147;ENST00000257899;ENST00000551444","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005765(lysosomal membrane);GO:1904115(axon cytoplasm);GO:0005829(cytosol);GO:0005739(mitochondrion);GO:0005515(protein binding);GO:0005615(extracellular space);GO:0005759(mitochondrial matrix);GO:0005764(lysosome);GO:0031083(BLOC-1 complex);GO:0005758(mitochondrial intermembrane space);GO:0070062(extracellular exosome);GO:0016197(endosomal transport);GO:0008089(anterograde axonal transport);GO:0032438(melanosome organization);GO:0048490(anterograde synaptic vesicle transport);GO:0031175(neuron projection development);GO:0032418(lysosome localization);GO:0099078(BORC complex);GO:0009060(aerobic respiration);GO:0018394(peptidyl-lysine acetylation);GO:0060155(platelet dense granule organization);GO:0007601(visual perception);GO:0055114(oxidation-reduction process);GO:0004745(retinol dehydrogenase activity);GO:0016491(oxidoreductase activity);GO:0005783(endoplasmic reticulum);GO:0005788(endoplasmic reticulum lumen);GO:0044297(cell body);GO:0050896(response to stimulus);GO:0005789(endoplasmic reticulum membrane);GO:0001523(retinoid metabolic process);GO:0042572(retinol metabolic process);GO:0005769(early endosome);GO:0042572(retinol metabolic process)","00830(Retinol metabolism);00830(Retinol metabolism)","K00061","EC:1.1.1.315","biogenesis of lysosomal organelles complex 1 subunit 1 [Source:HGNC Symbol;Acc:HGNC:4200];retinol dehydrogenase 5 [Source:HGNC Symbol;Acc:HGNC:9940]",{"v":3.3870649911032,"d":"3.39"},{"v":6.96825790658363,"d":"6.97"},{"v":0.486070555440133,"d":"0.49"},{"v":-1.04076235184729,"d":"-1.04"},{"v":0.0497912079500107,"d":"0.05"},{"v":0.525659361748613,"d":"0.53"},"down","yes"]
["ENSG00000152223","EPG5","ENST00000282041;ENST00000587974;ENST00000587262;ENST00000585906;ENST00000592272;ENST00000586655;ENST00000590884","GO:0006914(autophagy);GO:0005737(cytoplasm);GO:0097352(autophagosome maturation);GO:0032456(endocytic recycling);GO:0032456(endocytic recycling)","NA","NA","NA","ectopic P-granules autophagy protein 5 homolog [Source:HGNC Symbol;Acc:HGNC:29331]",{"v":3.65063189447898,"d":"3.65"},{"v":1.22495138091408,"d":"1.22"},{"v":2.98022595129842,"d":"2.98"},{"v":1.57542171540558,"d":"1.58"},{"v":0.0499138444715297,"d":"0.05"},{"v":0.526027765112182,"d":"0.53"},"up","yes"]
["MSTRG.2460","EEF1G;AP002990.1;TUT1","ENST00000329251;ENST00000526409;ENST00000525340;ENST00000476907;ENST00000308436;ENST00000524420;ENST00000532986;ENST00000494385;ENST00000478537;ENST00000469480;ENST00000496634;ENST00000534745;ENST00000463241","GO:0005737(cytoplasm);GO:0005634(nucleus);GO:0016020(membrane);GO:0006412(translation);GO:0005783(endoplasmic reticulum);GO:0005515(protein binding);GO:0003746(translation elongation factor activity);GO:0006414(translational elongation);GO:0005829(cytosol);GO:0045296(cadherin binding);GO:0070062(extracellular exosome);GO:0009615(response to virus);GO:0004364(glutathione transferase activity);GO:0006749(glutathione metabolic process);GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0003730(mRNA 3'-UTR binding);GO:0006378(mRNA polyadenylation);GO:0050265(RNA uridylyltransferase activity);GO:0006397(mRNA processing);GO:0016607(nuclear speck);GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0005730(nucleolus);GO:0016740(transferase activity);GO:0016779(nucleotidyltransferase activity);GO:0019899(enzyme binding);GO:0005847(mRNA cleavage and polyadenylation specificity factor complex);GO:0004652(polynucleotide adenylyltransferase activity);GO:0098789(pre-mRNA cleavage required for polyadenylation);GO:0016180(snRNA processing);GO:0016180(snRNA processing)","05134(Legionellosis);05134(Legionellosis)","K03233","NA","eukaryotic translation elongation factor 1 gamma [Source:HGNC Symbol;Acc:HGNC:3213];terminal uridylyl transferase 1, U6 snRNA-specific [Source:HGNC Symbol;Acc:HGNC:26184]",{"v":93.3135366864929,"d":"93.31"},{"v":190.885929488013,"d":"190.89"},{"v":0.488844499627473,"d":"0.49"},{"v":-1.03255247489081,"d":"-1.03"},{"v":0.0499318739634195,"d":"0.05"},{"v":0.526027765112182,"d":"0.53"},"down","yes"]
["ENSG00000175548","ALG10B","ENST00000308742;ENST00000551464;ENST00000553138","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016740(transferase activity);GO:0016757(transferase activity, transferring glycosyl groups);GO:0005783(endoplasmic reticulum);GO:0005886(plasma membrane);GO:0005789(endoplasmic reticulum membrane);GO:0006488(dolichol-linked oligosaccharide biosynthetic process);GO:0006486(protein glycosylation);GO:0004583(dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity);GO:0060050(positive regulation of protein glycosylation);GO:1901980(positive regulation of inward rectifier potassium channel activity);GO:1901980(positive regulation of inward rectifier potassium channel activity)","00510(N-Glycan biosynthesis);00510(N-Glycan biosynthesis)","K03850","EC:2.4.1.256","ALG10B, alpha-1,2-glucosyltransferase [Source:HGNC Symbol;Acc:HGNC:31088]",{"v":0.390952637173552,"d":"0.39"},{"v":0.127522548694209,"d":"0.13"},{"v":3.06575300742327,"d":"3.07"},{"v":1.61624147086516,"d":"1.62"},{"v":0.050019754395925,"d":"0.05"},{"v":0.526027765112182,"d":"0.53"},"up","no"]
["MSTRG.4624","NDUFB1","ENST00000605997;ENST00000329559;ENST00000617122;ENST00000553666;ENST00000553514;ENST00000556555;ENST00000555441","GO:0016607(nuclear speck);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0055114(oxidation-reduction process);GO:0005739(mitochondrion);GO:0005743(mitochondrial inner membrane);GO:0070469(respiratory chain);GO:0003954(NADH dehydrogenase activity);GO:0070062(extracellular exosome);GO:0032981(mitochondrial respiratory chain complex I assembly);GO:0008137(NADH dehydrogenase (ubiquinone) activity);GO:0006120(mitochondrial electron transport, NADH to ubiquinone);GO:0005747(mitochondrial respiratory chain complex I);GO:0005747(mitochondrial respiratory chain complex I)","00190(Oxidative phosphorylation);04723(Retrograde endocannabinoid signaling);05010(Alzheimer's disease);05012(Parkinson's disease);05016(Huntington's disease);04932(Non-alcoholic fatty liver disease (NAFLD));04932(Non-alcoholic fatty liver disease (NAFLD))","K03957","NA","NADH:ubiquinone oxidoreductase subunit B1 [Source:HGNC Symbol;Acc:HGNC:7695]",{"v":5.71502215466195,"d":"5.72"},{"v":11.7334745483871,"d":"11.73"},{"v":0.487069889749541,"d":"0.49"},{"v":-1.03779929514505,"d":"-1.04"},{"v":0.0500744566612672,"d":"0.05"},{"v":0.526027765112182,"d":"0.53"},"down","no"]
["ENSG00000197375","SLC22A5","ENST00000245407;ENST00000448810;ENST00000447841;ENST00000415928;ENST00000479605;ENST00000475308;ENST00000461013","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005215(transporter activity);GO:0055085(transmembrane transport);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0015293(symporter activity);GO:0006811(ion transport);GO:0006814(sodium ion transport);GO:0022857(transmembrane transporter activity);GO:0005886(plasma membrane);GO:0015711(organic anion transport);GO:0005887(integral component of plasma membrane);GO:0070062(extracellular exosome);GO:0008514(organic anion transmembrane transporter activity);GO:0005515(protein binding);GO:0006855(drug transmembrane transport);GO:0030165(PDZ domain binding);GO:0016324(apical plasma membrane);GO:0015226(carnitine transmembrane transporter activity);GO:0015238(drug transmembrane transporter activity);GO:0015491(cation:cation antiporter activity);GO:0015651(quaternary ammonium group transmembrane transporter activity);GO:0009437(carnitine metabolic process);GO:0015697(quaternary ammonium group transport);GO:0015879(carnitine transport);GO:0015893(drug transport);GO:0052106(quorum sensing involved in interaction with host);GO:0060731(positive regulation of intestinal epithelial structure maintenance);GO:0070715(sodium-dependent organic cation transport);GO:1902603(carnitine transmembrane transport);GO:0031526(brush border membrane);GO:0031526(brush border membrane)","05231(Choline metabolism in cancer);05231(Choline metabolism in cancer)","K08202","NA","solute carrier family 22 member 5 [Source:HGNC Symbol;Acc:HGNC:10969]",{"v":0.532166710431655,"d":"0.53"},{"v":0.174192883719112,"d":"0.17"},{"v":3.05504277252669,"d":"3.06"},{"v":1.61119257882638,"d":"1.61"},{"v":0.0500893794305003,"d":"0.05"},{"v":0.526027765112182,"d":"0.53"},"up","no"]
["ENSG00000149970","CNKSR2","ENST00000425654;ENST00000379510;ENST00000543067","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0009966(regulation of signal transduction);GO:0070062(extracellular exosome);GO:0042802(identical protein binding);GO:0014069(postsynaptic density);GO:0043005(neuron projection);GO:0043025(neuronal cell body);GO:0045211(postsynaptic membrane);GO:0045211(postsynaptic membrane)","NA","NA","NA","connector enhancer of kinase suppressor of Ras 2 [Source:HGNC Symbol;Acc:HGNC:19701]",{"v":0.470121968575419,"d":"0.47"},{"v":0.1510522,"d":"0.15"},{"v":3.1123146076351,"d":"3.11"},{"v":1.63798790220517,"d":"1.64"},{"v":0.0501353412913045,"d":"0.05"},{"v":0.526027765112182,"d":"0.53"},"up","no"]
["MSTRG.11645","IGFBP7","ENST00000295666;ENST00000514062","GO:0005615(extracellular space);GO:0007155(cell adhesion);GO:0005576(extracellular region);GO:0005520(insulin-like growth factor binding);GO:0001558(regulation of cell growth);GO:0005515(protein binding);GO:0070062(extracellular exosome);GO:0044267(cellular protein metabolic process);GO:0043687(post-translational protein modification);GO:0031012(extracellular matrix);GO:0005788(endoplasmic reticulum lumen);GO:0019838(growth factor binding);GO:0008285(negative regulation of cell proliferation);GO:0007566(embryo implantation);GO:0009408(response to heat);GO:0014070(response to organic cyclic compound);GO:0032526(response to retinoic acid);GO:0032870(cellular response to hormone stimulus);GO:0050810(regulation of steroid biosynthetic process);GO:0051414(response to cortisol);GO:0051414(response to cortisol)","NA","NA","NA","insulin like growth factor binding protein 7 [Source:HGNC Symbol;Acc:HGNC:5476]",{"v":3.97432314145078,"d":"3.97"},{"v":8.18512503834197,"d":"8.19"},{"v":0.485554359015124,"d":"0.49"},{"v":-1.04229527691224,"d":"-1.04"},{"v":0.050143178849495,"d":"0.05"},{"v":0.526027765112182,"d":"0.53"},"down","no"]
["ENSG00000114933","INO80D","ENST00000403263;ENST00000424117;ENST00000414320","GO:0005634(nucleus);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0006281(DNA repair);GO:0006310(DNA recombination);GO:0006974(cellular response to DNA damage stimulus);GO:0005654(nucleoplasm);GO:0016579(protein deubiquitination);GO:0016579(protein deubiquitination)","NA","NA","NA","INO80 complex subunit D [Source:HGNC Symbol;Acc:HGNC:25997]",{"v":2.85774879858067,"d":"2.86"},{"v":0.959373476101023,"d":"0.96"},{"v":2.97876569424747,"d":"2.98"},{"v":1.57471464757487,"d":"1.57"},{"v":0.0503771524417031,"d":"0.05"},{"v":0.527096768562979,"d":"0.53"},"up","no"]
["MSTRG.5923","AC007342.3","MSTRG.5923.2;MSTRG.5923.3;ENST00000565421;ENST00000565598","NA","NA","NA","NA",null,{"v":6.87137216044317,"d":"6.87"},{"v":14.045269980714,"d":"14.05"},{"v":0.489230336610009,"d":"0.49"},{"v":-1.03141422838953,"d":"-1.03"},{"v":0.0504047267425551,"d":"0.05"},{"v":0.527096768562979,"d":"0.53"},"down","no"]
["MSTRG.2830","POU2AF1","ENST00000393067;ENST00000525890;ENST00000525584;ENST00000526535;ENST00000525499;ENST00000529065;ENST00000530793","GO:0005634(nucleus);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0005515(protein binding);GO:0003713(transcription coactivator activity);GO:0006366(transcription from RNA polymerase II promoter);GO:0003712(transcription cofactor activity);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0006959(humoral immune response);GO:0000979(RNA polymerase II core promoter sequence-specific DNA binding);GO:0001105(RNA polymerase II transcription coactivator activity);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0090575(RNA polymerase II transcription factor complex);GO:0003677(DNA binding);GO:0003677(DNA binding)","NA","NA","NA","POU class 2 associating factor 1 [Source:HGNC Symbol;Acc:HGNC:9211]",{"v":2.02533703411543,"d":"2.03"},{"v":0.676324472626753,"d":"0.68"},{"v":2.99462331482594,"d":"2.99"},{"v":1.58237454190883,"d":"1.58"},{"v":0.0504227432211974,"d":"0.05"},{"v":0.527096768562979,"d":"0.53"},"up","no"]
["MSTRG.1323","SNRPE","ENST00000414487;ENST00000483099;ENST00000475035;ENST00000367208","GO:0003723(RNA binding);GO:0006397(mRNA processing);GO:0008380(RNA splicing);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0030529(intracellular ribonucleoprotein complex);GO:0005829(cytosol);GO:0005515(protein binding);GO:0005681(spliceosomal complex);GO:0000398(mRNA splicing, via spliceosome);GO:0000387(spliceosomal snRNP assembly);GO:0005685(U1 snRNP);GO:0005654(nucleoplasm);GO:0070062(extracellular exosome);GO:0005682(U5 snRNP);GO:0046540(U4/U6 x U5 tri-snRNP complex);GO:0006369(termination of RNA polymerase II transcription);GO:0034709(methylosome);GO:0005697(telomerase holoenzyme complex);GO:0051170(nuclear import);GO:0034719(SMN-Sm protein complex);GO:0071013(catalytic step 2 spliceosome);GO:0071011(precatalytic spliceosome);GO:0005686(U2 snRNP);GO:0005689(U12-type spliceosomal complex);GO:0000245(spliceosomal complex assembly);GO:0042633(hair cycle);GO:0008334(histone mRNA metabolic process);GO:0005683(U7 snRNP);GO:0005687(U4 snRNP);GO:0034715(pICln-Sm protein complex);GO:0030532(small nuclear ribonucleoprotein complex);GO:0030532(small nuclear ribonucleoprotein complex)","03040(Spliceosome);03040(Spliceosome)","K11097","NA","small nuclear ribonucleoprotein polypeptide E [Source:HGNC Symbol;Acc:HGNC:11161]",{"v":3.35986755970149,"d":"3.36"},{"v":6.97137969945726,"d":"6.97"},{"v":0.48195159416766,"d":"0.48"},{"v":-1.05303984129759,"d":"-1.05"},{"v":0.0504266347949255,"d":"0.05"},{"v":0.527096768562979,"d":"0.53"},"down","no"]
["ENSG00000148803","FUOM","ENST00000278025;ENST00000447176;ENST00000368552;ENST00000368551;ENST00000478895;ENST00000465384","GO:0016853(isomerase activity);GO:0005829(cytosol);GO:0016857(racemase and epimerase activity, acting on carbohydrates and derivatives);GO:0042806(fucose binding);GO:0048029(monosaccharide binding);GO:0005996(monosaccharide metabolic process);GO:0006004(fucose metabolic process);GO:0036065(fucosylation);GO:0045665(negative regulation of neuron differentiation);GO:0060180(female mating behavior);GO:0060180(female mating behavior)","NA","NA","NA","fucose mutarotase [Source:HGNC Symbol;Acc:HGNC:24733]",{"v":2.65405491121495,"d":"2.65"},{"v":5.55481438239875,"d":"5.55"},{"v":0.477793627024643,"d":"0.48"},{"v":-1.06554048412631,"d":"-1.07"},{"v":0.0505402477974649,"d":"0.05"},{"v":0.527366386491199,"d":"0.53"},"down","no"]
["MSTRG.12178","XRCC4","ENST00000396027;ENST00000542685;ENST00000282268;ENST00000509268","GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0003677(DNA binding);GO:0005829(cytosol);GO:0005515(protein binding);GO:0006281(DNA repair);GO:0006310(DNA recombination);GO:0006974(cellular response to DNA damage stimulus);GO:0006302(double-strand break repair);GO:0042802(identical protein binding);GO:0008022(protein C-terminus binding);GO:0006303(double-strand break repair via nonhomologous end joining);GO:0075713(establishment of integrated proviral latency);GO:0051103(DNA ligation involved in DNA repair);GO:0070419(nonhomologous end joining complex);GO:0010165(response to X-ray);GO:0005958(DNA-dependent protein kinase-DNA ligase 4 complex);GO:0032807(DNA ligase IV complex);GO:0051351(positive regulation of ligase activity);GO:0071285(cellular response to lithium ion);GO:0071285(cellular response to lithium ion)","03450(Non-homologous end-joining);03450(Non-homologous end-joining)","K10886","NA","X-ray repair cross complementing 4 [Source:HGNC Symbol;Acc:HGNC:12831]",{"v":1.96345800896861,"d":"1.96"},{"v":4.05861729783259,"d":"4.06"},{"v":0.483775104890315,"d":"0.48"},{"v":-1.04759156487376,"d":"-1.05"},{"v":0.0506044404118723,"d":"0.05"},{"v":0.527366386491199,"d":"0.53"},"down","no"]
["ENSG00000171150","SOCS5","ENST00000306503;ENST00000394861","GO:0016567(protein ubiquitination);GO:0035556(intracellular signal transduction);GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0007259(JAK-STAT cascade);GO:0007173(epidermal growth factor receptor signaling pathway);GO:0005829(cytosol);GO:0040008(regulation of growth);GO:0043687(post-translational protein modification);GO:0004860(protein kinase inhibitor activity);GO:0019221(cytokine-mediated signaling pathway);GO:0046426(negative regulation of JAK-STAT cascade);GO:0030971(receptor tyrosine kinase binding);GO:0009968(negative regulation of signal transduction);GO:0016049(cell growth);GO:0032436(positive regulation of proteasomal ubiquitin-dependent protein catabolic process);GO:0005154(epidermal growth factor receptor binding);GO:0007175(negative regulation of epidermal growth factor-activated receptor activity);GO:0032715(negative regulation of interleukin-6 production);GO:0045627(positive regulation of T-helper 1 cell differentiation);GO:0045629(negative regulation of T-helper 2 cell differentiation);GO:0050728(negative regulation of inflammatory response);GO:0071404(cellular response to low-density lipoprotein particle stimulus);GO:0071638(negative regulation of monocyte chemotactic protein-1 production);GO:0097699(vascular endothelial cell response to fluid shear stress);GO:0097699(vascular endothelial cell response to fluid shear stress)","04630(Jak-STAT signaling pathway);04917(Prolactin signaling pathway);04917(Prolactin signaling pathway)","K04698","NA","suppressor of cytokine signaling 5 [Source:HGNC Symbol;Acc:HGNC:16852]",{"v":0.188548407032181,"d":"0.19"},{"v":0.411198861541518,"d":"0.41"},{"v":0.458533387775792,"d":"0.46"},{"v":-1.12490130845014,"d":"-1.12"},{"v":0.0506584240123393,"d":"0.05"},{"v":0.527366386491199,"d":"0.53"},"down","no"]
["MSTRG.8321","NOSIP","ENST00000596358;MSTRG.8321.6;ENST00000339093;ENST00000598820;ENST00000601340;MSTRG.8321.8;ENST00000601107;ENST00000594932;ENST00000598839;ENST00000601015;ENST00000598544;ENST00000593345;ENST00000599425;ENST00000596477;ENST00000598550;ENST00000599537","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0050999(regulation of nitric-oxide synthase activity);GO:0003723(RNA binding);GO:0016740(transferase activity);GO:0007275(multicellular organism development);GO:0061630(ubiquitin protein ligase activity);GO:0005515(protein binding);GO:0005829(cytosol);GO:0016567(protein ubiquitination);GO:0000139(Golgi membrane);GO:0043086(negative regulation of catalytic activity);GO:0051001(negative regulation of nitric-oxide synthase activity);GO:0004842(ubiquitin-protein transferase activity);GO:0004842(ubiquitin-protein transferase activity)","NA","NA","NA","nitric oxide synthase interacting protein [Source:HGNC Symbol;Acc:HGNC:17946]",{"v":10.9657389757939,"d":"10.97"},{"v":22.4086449600266,"d":"22.41"},{"v":0.489353059738998,"d":"0.49"},{"v":-1.0310523746095,"d":"-1.03"},{"v":0.0507283042500416,"d":"0.05"},{"v":0.527366386491199,"d":"0.53"},"down","no"]
["MSTRG.10970","RPL29","ENST00000480306;ENST00000495383;ENST00000492277;ENST00000294189;ENST00000475248;ENST00000481629;ENST00000466397;ENST00000486565;MSTRG.10970.1","GO:0003723(RNA binding);GO:0016020(membrane);GO:0006412(translation);GO:0030529(intracellular ribonucleoprotein complex);GO:0005622(intracellular);GO:0003735(structural constituent of ribosome);GO:0005840(ribosome);GO:0008201(heparin binding);GO:0005829(cytosol);GO:0045296(cadherin binding);GO:0002181(cytoplasmic translation);GO:0006413(translational initiation);GO:0006364(rRNA processing);GO:0000184(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay);GO:0019083(viral transcription);GO:0006614(SRP-dependent cotranslational protein targeting to membrane);GO:0022625(cytosolic large ribosomal subunit);GO:0007566(embryo implantation);GO:0007566(embryo implantation)","03010(Ribosome);03010(Ribosome)","K02905","NA","ribosomal protein L29 [Source:HGNC Symbol;Acc:HGNC:10331]",{"v":105.154201172821,"d":"105.15"},{"v":214.361375325128,"d":"214.36"},{"v":0.490546400970467,"d":"0.49"},{"v":-1.02753848691618,"d":"-1.03"},{"v":0.0508675993289041,"d":"0.05"},{"v":0.527366386491199,"d":"0.53"},"down","no"]
["MSTRG.1660","CCNY","MSTRG.1660.9;ENST00000339497;ENST00000374704;ENST00000493157;ENST00000465416;ENST00000497692;ENST00000265375;ENST00000490012;ENST00000470025","GO:0005634(nucleus);GO:0016020(membrane);GO:0051301(cell division);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0007049(cell cycle);GO:0016055(Wnt signaling pathway);GO:0019901(protein kinase binding);GO:0000079(regulation of cyclin-dependent protein serine/threonine kinase activity);GO:0070062(extracellular exosome);GO:0000086(G2/M transition of mitotic cell cycle);GO:0045737(positive regulation of cyclin-dependent protein serine/threonine kinase activity);GO:0060828(regulation of canonical Wnt signaling pathway);GO:0000308(cytoplasmic cyclin-dependent protein kinase holoenzyme complex);GO:0016538(cyclin-dependent protein serine/threonine kinase regulator activity);GO:0016538(cyclin-dependent protein serine/threonine kinase regulator activity)","NA","NA","NA","cyclin Y [Source:HGNC Symbol;Acc:HGNC:23354]",{"v":21.3439483430869,"d":"21.34"},{"v":7.20235392950034,"d":"7.20"},{"v":2.96346840935761,"d":"2.96"},{"v":1.5672866784247,"d":"1.57"},{"v":0.0508954070954535,"d":"0.05"},{"v":0.527366386491199,"d":"0.53"},"up","no"]
["MSTRG.9941","FP236383.3;FP236383.2","ENST00000627981;MSTRG.9941.1;ENST00000625598","NA","NA","NA","NA",null,{"v":5.87796006166932,"d":"5.88"},{"v":12.0570798118022,"d":"12.06"},{"v":0.487511085056899,"d":"0.49"},{"v":-1.03649307156399,"d":"-1.04"},{"v":0.0509304701769772,"d":"0.05"},{"v":0.527366386491199,"d":"0.53"},"down","no"]
["MSTRG.10871","FYCO1","ENST00000296137;ENST00000433878;ENST00000535325;ENST00000438446;ENST00000471739","GO:0016021(integral component of membrane);GO:0006810(transport);GO:0043231(intracellular membrane-bounded organelle);GO:0016020(membrane);GO:0005794(Golgi apparatus);GO:0046872(metal ion binding);GO:0005515(protein binding);GO:0031410(cytoplasmic vesicle);GO:0005764(lysosome);GO:0061077(chaperone-mediated protein folding);GO:0005768(endosome);GO:0005770(late endosome);GO:0005776(autophagosome);GO:0051082(unfolded protein binding);GO:0044183(protein binding involved in protein folding);GO:0006458('de novo' protein folding);GO:0072383(plus-end-directed vesicle transport along microtubule);GO:1901098(positive regulation of autophagosome maturation);GO:1901098(positive regulation of autophagosome maturation)","NA","NA","NA","FYVE and coiled-coil domain containing 1 [Source:HGNC Symbol;Acc:HGNC:14673]",{"v":3.84121002417088,"d":"3.84"},{"v":1.28956613816751,"d":"1.29"},{"v":2.97868400113955,"d":"2.98"},{"v":1.57467508089863,"d":"1.57"},{"v":0.0509388103349784,"d":"0.05"},{"v":0.527366386491199,"d":"0.53"},"up","no"]
["MSTRG.1314","CYB5R1","ENST00000367249;ENST00000446185;ENST00000478009;ENST00000497655;ENST00000473599;ENST00000483915;ENST00000482572","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0006629(lipid metabolic process);GO:0005739(mitochondrion);GO:0006694(steroid biosynthetic process);GO:0008202(steroid metabolic process);GO:0016126(sterol biosynthetic process);GO:0005515(protein binding);GO:0005886(plasma membrane);GO:0003674(molecular_function);GO:0008150(biological_process);GO:0005789(endoplasmic reticulum membrane);GO:0070062(extracellular exosome);GO:0002576(platelet degranulation);GO:1903955(positive regulation of protein targeting to mitochondrion);GO:0015701(bicarbonate transport);GO:0031092(platelet alpha granule membrane);GO:0004128(cytochrome-b5 reductase activity, acting on NAD(P)H);GO:0004128(cytochrome-b5 reductase activity, acting on NAD(P)H)","00520(Amino sugar and nucleotide sugar metabolism);00520(Amino sugar and nucleotide sugar metabolism)","K00326","EC:1.6.2.2","cytochrome b5 reductase 1 [Source:HGNC Symbol;Acc:HGNC:13397]",{"v":3.25466347757549,"d":"3.25"},{"v":6.658285714254,"d":"6.66"},{"v":0.488814030705822,"d":"0.49"},{"v":-1.03264239864398,"d":"-1.03"},{"v":0.0509753709598174,"d":"0.05"},{"v":0.527366386491199,"d":"0.53"},"down","no"]
["MSTRG.12050","GZMA","ENST00000274306","GO:0005634(nucleus);GO:0016787(hydrolase activity);GO:0042803(protein homodimerization activity);GO:0008233(peptidase activity);GO:0006508(proteolysis);GO:0005576(extracellular region);GO:0004252(serine-type endopeptidase activity);GO:0006955(immune response);GO:0006915(apoptotic process);GO:0008236(serine-type peptidase activity);GO:0019835(cytolysis);GO:0005515(protein binding);GO:0043065(positive regulation of apoptotic process);GO:0001772(immunological synapse);GO:0051603(proteolysis involved in cellular protein catabolic process);GO:0043392(negative regulation of DNA binding);GO:0032078(negative regulation of endodeoxyribonuclease activity);GO:0051354(negative regulation of oxidoreductase activity)","04080(Neuroactive ligand-receptor interaction)","K01352","EC:3.4.21.78","granzyme A [Source:HGNC Symbol;Acc:HGNC:4708]",{"v":58.591625,"d":"58.59"},{"v":119.416969,"d":"119.42"},{"v":0.490647397021105,"d":"0.49"},{"v":-1.02724148850014,"d":"-1.03"},{"v":0.0510583598180832,"d":"0.05"},{"v":0.527366386491199,"d":"0.53"},"down","no"]
["ENSG00000139514","SLC7A1","ENST00000380752;ENST00000473577","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005515(protein binding);GO:0015171(amino acid transmembrane transporter activity);GO:0003333(amino acid transmembrane transport);GO:0015181(arginine transmembrane transporter activity);GO:0006865(amino acid transport);GO:0015809(arginine transport);GO:1903826(arginine transmembrane transport);GO:0005886(plasma membrane);GO:0005887(integral component of plasma membrane);GO:0005887(integral component of plasma membrane)","05206(MicroRNAs in cancer);05206(MicroRNAs in cancer)","K13863","NA","solute carrier family 7 member 1 [Source:HGNC Symbol;Acc:HGNC:11057]",{"v":2.95969386700468,"d":"2.96"},{"v":0.99456621723869,"d":"0.99"},{"v":2.97586406586578,"d":"2.98"},{"v":1.57330862725901,"d":"1.57"},{"v":0.0511416355933995,"d":"0.05"},{"v":0.527366386491199,"d":"0.53"},"up","no"]
["ENSG00000116396","KCNC4","ENST00000369787;ENST00000459877;ENST00000636402;ENST00000469655","GO:0005249(voltage-gated potassium channel activity);GO:0006813(potassium ion transport);GO:0008076(voltage-gated potassium channel complex);GO:0071805(potassium ion transmembrane transport);GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0055085(transmembrane transport);GO:0005216(ion channel activity);GO:0006811(ion transport);GO:0005244(voltage-gated ion channel activity);GO:0005267(potassium channel activity);GO:0034765(regulation of ion transmembrane transport);GO:0051260(protein homooligomerization);GO:0005886(plasma membrane);GO:0007268(chemical synaptic transmission);GO:0046928(regulation of neurotransmitter secretion);GO:0031594(neuromuscular junction);GO:0043679(axon terminus);GO:0043679(axon terminus)","NA","NA","NA","potassium voltage-gated channel subfamily C member 4 [Source:HGNC Symbol;Acc:HGNC:6236]",{"v":0.148125187365226,"d":"0.15"},{"v":0.0481496231131699,"d":"0.05"},{"v":3.07635195849977,"d":"3.08"},{"v":1.62122056823302,"d":"1.62"},{"v":0.0511585626219994,"d":"0.05"},{"v":0.527366386491199,"d":"0.53"},"up","no"]
["MSTRG.4737","CRIP1;C14orf80;AL928654.4","ENST00000409393;ENST00000461556;ENST00000392531;ENST00000330233;ENST00000460959;ENST00000551538;ENST00000451719;ENST00000553228;ENST00000443229;ENST00000546536;ENST00000496700;ENST00000546492;ENST00000354560;ENST00000463869;ENST00000548920;ENST00000392522;ENST00000392523;ENST00000477724;ENST00000329886;ENST00000421892;ENST00000460900","GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0008270(zinc ion binding);GO:0006955(immune response);GO:0007507(heart development);GO:0008283(cell proliferation);GO:0010033(response to organic substance);GO:0042277(peptide binding);GO:0008301(DNA binding, bending);GO:0071493(cellular response to UV-B);GO:0008630(intrinsic apoptotic signaling pathway in response to DNA damage);GO:0010468(regulation of gene expression);GO:0003680(AT DNA binding);GO:0010043(response to zinc ion);GO:0060741(prostate gland stromal morphogenesis);GO:0071236(cellular response to antibiotic);GO:0071236(cellular response to antibiotic)","NA","NA","NA","cysteine rich protein 1 [Source:HGNC Symbol;Acc:HGNC:2360];chromosome 14 open reading frame 80 [Source:HGNC Symbol;Acc:HGNC:20127]",{"v":3.71479725717277,"d":"3.71"},{"v":7.58443361926702,"d":"7.58"},{"v":0.489792309307834,"d":"0.49"},{"v":-1.02975797392658,"d":"-1.03"},{"v":0.0511710965366365,"d":"0.05"},{"v":0.527366386491199,"d":"0.53"},"down","no"]
["MSTRG.13442","INTS1","ENST00000404767;ENST00000493531;ENST00000468115;ENST00000482994;ENST00000483196;ENST00000493446;ENST00000479671","GO:0005634(nucleus);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005654(nucleoplasm);GO:0031965(nuclear membrane);GO:0042795(snRNA transcription from RNA polymerase II promoter);GO:0032039(integrator complex);GO:0016180(snRNA processing);GO:0034474(U2 snRNA 3'-end processing);GO:0034474(U2 snRNA 3'-end processing)","NA","NA","NA","integrator complex subunit 1 [Source:HGNC Symbol;Acc:HGNC:24555]",{"v":6.08907601787685,"d":"6.09"},{"v":2.05466743467226,"d":"2.05"},{"v":2.96353361868906,"d":"2.96"},{"v":1.56731842370795,"d":"1.57"},{"v":0.0511742780718077,"d":"0.05"},{"v":0.527366386491199,"d":"0.53"},"up","no"]
["MSTRG.3531","IRAK3","ENST00000261233;ENST00000545837;ENST00000457197","GO:0005737(cytoplasm);GO:0005634(nucleus);GO:0045824(negative regulation of innate immune response);GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0007165(signal transduction);GO:0000287(magnesium ion binding);GO:0002755(MyD88-dependent toll-like receptor signaling pathway);GO:0034122(negative regulation of toll-like receptor signaling pathway);GO:0042803(protein homodimerization activity);GO:0046982(protein heterodimerization activity);GO:0032496(response to lipopolysaccharide);GO:0032715(negative regulation of interleukin-6 production);GO:0032720(negative regulation of tumor necrosis factor production);GO:0051092(positive regulation of NF-kappaB transcription factor activity);GO:0043242(negative regulation of protein complex disassembly);GO:0019221(cytokine-mediated signaling pathway);GO:0032695(negative regulation of interleukin-12 production);GO:0032088(negative regulation of NF-kappaB transcription factor activity);GO:0070498(interleukin-1-mediated signaling pathway);GO:0070555(response to interleukin-1);GO:0009615(response to virus);GO:0043407(negative regulation of MAP kinase activity);GO:0032494(response to peptidoglycan);GO:0042177(negative regulation of protein catabolic process);GO:0001960(negative regulation of cytokine-mediated signaling pathway);GO:0010933(positive regulation of macrophage tolerance induction);GO:0010936(negative regulation of macrophage cytokine production);GO:0043244(regulation of protein complex disassembly);GO:0043330(response to exogenous dsRNA);GO:0046777(protein autophosphorylation);GO:0046777(protein autophosphorylation)","04722(Neurotrophin signaling pathway);04722(Neurotrophin signaling pathway)","K04732","EC:2.7.11.1","interleukin 1 receptor associated kinase 3 [Source:HGNC Symbol;Acc:HGNC:17020]",{"v":8.22154885085966,"d":"8.22"},{"v":2.7757616387445,"d":"2.78"},{"v":2.96190736845053,"d":"2.96"},{"v":1.56652652206945,"d":"1.57"},{"v":0.0512389950080818,"d":"0.05"},{"v":0.527366386491199,"d":"0.53"},"up","no"]
["ENSG00000141252","VPS53","ENST00000437048;ENST00000291074;ENST00000572259;ENST00000576019;ENST00000570359;ENST00000571805;ENST00000572607;ENST00000571456;ENST00000570771;ENST00000575207;ENST00000570510;ENST00000389040;ENST00000573028;ENST00000541903;ENST00000572334;ENST00000576149;ENST00000570650;ENST00000575100","GO:0006810(transport);GO:0016020(membrane);GO:0015031(protein transport);GO:0005794(Golgi apparatus);GO:0005829(cytosol);GO:0048471(perinuclear region of cytoplasm);GO:0005515(protein binding);GO:0005768(endosome);GO:0010008(endosome membrane);GO:0042147(retrograde transport, endosome to Golgi);GO:0055037(recycling endosome);GO:0032588(trans-Golgi network membrane);GO:0032456(endocytic recycling);GO:0007041(lysosomal transport);GO:0000938(GARP complex);GO:0005802(trans-Golgi network);GO:1990745(EARP complex);GO:1990745(EARP complex)","NA","NA","NA","VPS53, GARP complex subunit [Source:HGNC Symbol;Acc:HGNC:25608]",{"v":1.81802684008804,"d":"1.82"},{"v":0.611478277620939,"d":"0.61"},{"v":2.97316667921776,"d":"2.97"},{"v":1.57200034469201,"d":"1.57"},{"v":0.0512575560935007,"d":"0.05"},{"v":0.527366386491199,"d":"0.53"},"up","no"]
["MSTRG.5815","AC009133.1","ENST00000563806;ENST00000569809;ENST00000569039;ENST00000564980;ENST00000569981","NA","NA","NA","NA",null,{"v":0.807611907897995,"d":"0.81"},{"v":0.257734006189651,"d":"0.26"},{"v":3.13350930999661,"d":"3.13"},{"v":1.64777927953626,"d":"1.65"},{"v":0.0512609717450793,"d":"0.05"},{"v":0.527366386491199,"d":"0.53"},"up","no"]
["ENSG00000127914","AKAP9","ENST00000356239;ENST00000487258;ENST00000394534;ENST00000493976;ENST00000358100;ENST00000493453;ENST00000435423;ENST00000359028;ENST00000394564;ENST00000487692;ENST00000619023;ENST00000438114","GO:0060307(regulation of ventricular cardiac muscle cell membrane repolarization);GO:0005737(cytoplasm);GO:0005794(Golgi apparatus);GO:0043231(intracellular membrane-bounded organelle);GO:0003677(DNA binding);GO:0007165(signal transduction);GO:0005813(centrosome);GO:0032947(protein complex scaffold);GO:0043547(positive regulation of GTPase activity);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0005815(microtubule organizing center);GO:0005829(cytosol);GO:0000165(MAPK cascade);GO:0006810(transport);GO:0000086(G2/M transition of mitotic cell cycle);GO:0010389(regulation of G2/M transition of mitotic cell cycle);GO:0097711(ciliary basal body docking);GO:0033138(positive regulation of peptidyl-serine phosphorylation);GO:0044325(ion channel binding);GO:0061337(cardiac conduction);GO:0005795(Golgi stack);GO:0005102(receptor binding);GO:0007268(chemical synaptic transmission);GO:0005088(Ras guanyl-nucleotide exchange factor activity);GO:0060306(regulation of membrane repolarization);GO:0008076(voltage-gated potassium channel complex);GO:0034237(protein kinase A regulatory subunit binding);GO:0086091(regulation of heart rate by cardiac conduction);GO:0071320(cellular response to cAMP);GO:0015459(potassium channel regulator activity);GO:0007020(microtubule nucleation);GO:1901018(positive regulation of potassium ion transmembrane transporter activity);GO:0098909(regulation of cardiac muscle cell action potential involved in regulation of contraction);GO:0051661(maintenance of centrosome location);GO:0005801(cis-Golgi network);GO:0007194(negative regulation of adenylate cyclase activity);GO:0051602(response to electrical stimulus);GO:0043025(neuronal cell body);GO:0044307(dendritic branch);GO:0097060(synaptic membrane);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0016310(phosphorylation)","NA","NA","NA","A-kinase anchoring protein 9 [Source:HGNC Symbol;Acc:HGNC:379]",{"v":2.93546558557075,"d":"2.94"},{"v":0.989331497776314,"d":"0.99"},{"v":2.96712031525196,"d":"2.97"},{"v":1.56906342857013,"d":"1.57"},{"v":0.051269839864683,"d":"0.05"},{"v":0.527366386491199,"d":"0.53"},"up","no"]
["MSTRG.12457","RPS14","ENST00000407193;ENST00000401695;ENST00000519690;ENST00000518139;ENST00000521466;ENST00000519855;ENST00000312037","GO:0003723(RNA binding);GO:0016020(membrane);GO:0006412(translation);GO:0030529(intracellular ribonucleoprotein complex);GO:0003735(structural constituent of ribosome);GO:0005840(ribosome);GO:0005515(protein binding);GO:0030218(erythrocyte differentiation);GO:0000028(ribosomal small subunit assembly);GO:0022627(cytosolic small ribosomal subunit);GO:0005730(nucleolus);GO:0005925(focal adhesion);GO:0000462(maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA));GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0031012(extracellular matrix);GO:0006413(translational initiation);GO:0006364(rRNA processing);GO:0048027(mRNA 5'-UTR binding);GO:0030490(maturation of SSU-rRNA);GO:0000184(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay);GO:0019083(viral transcription);GO:0006417(regulation of translation);GO:0006614(SRP-dependent cotranslational protein targeting to membrane);GO:0045182(translation regulator activity);GO:0070181(small ribosomal subunit rRNA binding);GO:0005739(mitochondrion);GO:0005739(mitochondrion)","03010(Ribosome);03010(Ribosome)","K02955","NA","ribosomal protein S14 [Source:HGNC Symbol;Acc:HGNC:10387]",{"v":78.161088853213,"d":"78.16"},{"v":158.955077602993,"d":"158.96"},{"v":0.491718100685204,"d":"0.49"},{"v":-1.02409663155691,"d":"-1.02"},{"v":0.0514082929130758,"d":"0.05"},{"v":0.528244045758338,"d":"0.53"},"down","no"]
["ENSG00000112782","CLIC5","ENST00000484572;ENST00000544153;ENST00000339561;ENST00000185206","GO:0006810(transport);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005794(Golgi apparatus);GO:0005244(voltage-gated ion channel activity);GO:0006811(ion transport);GO:0034765(regulation of ion transmembrane transport);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0005254(chloride channel activity);GO:0006821(chloride transport);GO:0034707(chloride channel complex);GO:0005815(microtubule organizing center);GO:0070062(extracellular exosome);GO:0005938(cell cortex);GO:0007605(sensory perception of sound);GO:0015629(actin cytoskeleton);GO:1902476(chloride transmembrane transport);GO:0007565(female pregnancy);GO:0060088(auditory receptor cell stereocilium organization);GO:0060088(auditory receptor cell stereocilium organization)","NA","NA","NA","chloride intracellular channel 5 [Source:HGNC Symbol;Acc:HGNC:13517]",{"v":0.0858058240524619,"d":"0.09"},{"v":0.189542573079916,"d":"0.19"},{"v":0.452699478846285,"d":"0.45"},{"v":-1.14337444915054,"d":"-1.14"},{"v":0.0514461393053199,"d":"0.05"},{"v":0.528244045758338,"d":"0.53"},"down","no"]
["MSTRG.9804","PREX1;AL133342.1","ENST00000371941;MSTRG.9804.1;ENST00000620554;ENST00000496915;ENST00000618168;MSTRG.9804.4;ENST00000482556","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0035556(intracellular signal transduction);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0005089(Rho guanyl-nucleotide exchange factor activity);GO:0035023(regulation of Rho protein signal transduction);GO:0005515(protein binding);GO:0005096(GTPase activator activity);GO:0005085(guanyl-nucleotide exchange factor activity);GO:0007186(G-protein coupled receptor signaling pathway);GO:0051056(regulation of small GTPase mediated signal transduction);GO:0006801(superoxide metabolic process);GO:0006469(negative regulation of protein kinase activity);GO:0030041(actin filament polymerization);GO:0019899(enzyme binding);GO:0005543(phospholipid binding);GO:0043065(positive regulation of apoptotic process);GO:0042119(neutrophil activation);GO:0032007(negative regulation of TOR signaling);GO:0030676(Rac guanyl-nucleotide exchange factor activity);GO:0030217(T cell differentiation);GO:0030335(positive regulation of cell migration);GO:0030593(neutrophil chemotaxis);GO:0030833(regulation of actin filament polymerization);GO:0043547(positive regulation of GTPase activity);GO:0045785(positive regulation of cell adhesion);GO:0050773(regulation of dendrite development);GO:0072593(reactive oxygen species metabolic process);GO:1900026(positive regulation of substrate adhesion-dependent cell spreading);GO:0030426(growth cone);GO:0043198(dendritic shaft);GO:0048471(perinuclear region of cytoplasm);GO:0048471(perinuclear region of cytoplasm)","04062(Chemokine signaling pathway);05167(Kaposi's sarcoma-associated herpesvirus infection);05167(Kaposi's sarcoma-associated herpesvirus infection)","K12365","NA","phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 1 [Source:HGNC Symbol;Acc:HGNC:32594]",{"v":63.5011620504502,"d":"63.50"},{"v":21.5057349134082,"d":"21.51"},{"v":2.95275480266704,"d":"2.95"},{"v":1.56206155976905,"d":"1.56"},{"v":0.0515974088410757,"d":"0.05"},{"v":0.528698515802731,"d":"0.53"},"up","no"]
["MSTRG.6701","SLFN12L","ENST00000361112;ENST00000628453;ENST00000590802;ENST00000260908;ENST00000587436","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005524(ATP binding);GO:0005524(ATP binding)","NA","NA","NA","schlafen family member 12 like [Source:HGNC Symbol;Acc:HGNC:33920]",{"v":3.01505970047807,"d":"3.02"},{"v":1.0115692972355,"d":"1.01"},{"v":2.98057652473031,"d":"2.98"},{"v":1.57559141421854,"d":"1.58"},{"v":0.0516398562912405,"d":"0.05"},{"v":0.528698515802731,"d":"0.53"},"up","no"]
["ENSG00000075407","ZNF37A","ENST00000351773;ENST00000361085;ENST00000477790;ENST00000638053","GO:0003676(nucleic acid binding);GO:0006355(regulation of transcription, DNA-templated);GO:0005622(intracellular);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding)","NA","NA","NA","zinc finger protein 37A [Source:HGNC Symbol;Acc:HGNC:13102]",{"v":0.790124232145565,"d":"0.79"},{"v":0.262192142683851,"d":"0.26"},{"v":3.01353131355385,"d":"3.01"},{"v":1.59145505589047,"d":"1.59"},{"v":0.0516689030310369,"d":"0.05"},{"v":0.528698515802731,"d":"0.53"},"up","no"]
["ENSG00000078699","CBFA2T2","ENST00000342704;ENST00000375279;ENST00000543126;ENST00000344201;ENST00000491618","GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0003714(transcription corepressor activity);GO:0005515(protein binding);GO:0045892(negative regulation of transcription, DNA-templated);GO:0010976(positive regulation of neuron projection development);GO:0010977(negative regulation of neuron projection development);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0030855(epithelial cell differentiation);GO:0045746(negative regulation of Notch signaling pathway);GO:0060575(intestinal epithelial cell differentiation);GO:0060575(intestinal epithelial cell differentiation)","NA","NA","NA","CBFA2/RUNX1 translocation partner 2 [Source:HGNC Symbol;Acc:HGNC:1536]",{"v":0.846526178492122,"d":"0.85"},{"v":0.280500200909379,"d":"0.28"},{"v":3.01791647830444,"d":"3.02"},{"v":1.59355287942213,"d":"1.59"},{"v":0.0517010402060665,"d":"0.05"},{"v":0.528698515802731,"d":"0.53"},"up","no"]
["ENSG00000128011","LRFN1","ENST00000248668","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005886(plasma membrane);GO:0030054(cell junction);GO:0045202(synapse);GO:0045211(postsynaptic membrane);GO:0005615(extracellular space);GO:0014069(postsynaptic density);GO:0007409(axonogenesis);GO:0005578(proteinaceous extracellular matrix);GO:0009986(cell surface)","NA","NA","NA","leucine rich repeat and fibronectin type III domain containing 1 [Source:HGNC Symbol;Acc:HGNC:29290]",{"v":3.50107,"d":"3.50"},{"v":1.172653,"d":"1.17"},{"v":2.98559761498073,"d":"2.99"},{"v":1.5780197388181,"d":"1.58"},{"v":0.0517819268894335,"d":"0.05"},{"v":0.528698515802731,"d":"0.53"},"up","no"]
["ENSG00000150995","ITPR1","ENST00000357086;ENST00000493491;ENST00000479831;ENST00000487016;ENST00000354582;ENST00000302640;ENST00000467056;ENST00000467545;ENST00000478515;ENST00000490572;ENST00000491868;ENST00000463980","GO:0006810(transport);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0055085(transmembrane transport);GO:0005216(ion channel activity);GO:0006811(ion transport);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005515(protein binding);GO:0007165(signal transduction);GO:0006915(apoptotic process);GO:0006816(calcium ion transport);GO:0070588(calcium ion transmembrane transport);GO:0048471(perinuclear region of cytoplasm);GO:0065009(regulation of molecular function);GO:0031410(cytoplasmic vesicle);GO:0005262(calcium channel activity);GO:0035091(phosphatidylinositol binding);GO:0005886(plasma membrane);GO:0005509(calcium ion binding);GO:0005220(inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity);GO:0048016(inositol phosphate-mediated signaling);GO:1903779(regulation of cardiac conduction);GO:0030168(platelet activation);GO:0050796(regulation of insulin secretion);GO:0070059(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress);GO:0031095(platelet dense tubular network membrane);GO:0030658(transport vesicle membrane);GO:0015278(calcium-release channel activity);GO:0051209(release of sequestered calcium ion into cytosol);GO:0010506(regulation of autophagy);GO:0001666(response to hypoxia);GO:0031094(platelet dense tubular network);GO:0015085(calcium ion transmembrane transporter activity);GO:0019855(calcium channel inhibitor activity);GO:0050849(negative regulation of calcium-mediated signaling);GO:0031088(platelet dense granule membrane);GO:0009791(post-embryonic development);GO:0032469(endoplasmic reticulum calcium ion homeostasis);GO:0042045(epithelial fluid transport);GO:0050882(voluntary musculoskeletal movement);GO:0005635(nuclear envelope);GO:0005637(nuclear inner membrane);GO:0005730(nucleolus);GO:0005955(calcineurin complex);GO:0014069(postsynaptic density);GO:0016529(sarcoplasmic reticulum);GO:0043234(protein complex);GO:0034220(ion transmembrane transport);GO:0034220(ion transmembrane transport)","04371(Apelin signaling pathway);04020(Calcium signaling pathway);04070(Phosphatidylinositol signaling system);04022(cGMP - PKG signaling pathway);04140(Autophagy - animal);04114(Oocyte meiosis);04210(Apoptosis);04218(Cellular senescence);04540(Gap junction);04611(Platelet activation);04621(NOD-like receptor signaling pathway);04922(Glucagon signaling pathway);04912(GnRH signaling pathway);04915(Estrogen signaling pathway);04921(Oxytocin signaling pathway);04918(Thyroid hormone synthesis);04924(Renin secretion);04925(Aldosterone synthesis and secretion);04927(Cortisol synthesis and secretion);04270(Vascular smooth muscle contraction);04970(Salivary secretion);04971(Gastric acid secretion);04972(Pancreatic secretion);04724(Glutamatergic synapse);04725(Cholinergic synapse);04728(Dopaminergic synapse);04726(Serotonergic synapse);04720(Long-term potentiation);04730(Long-term depression);04723(Retrograde endocannabinoid signaling);04750(Inflammatory mediator regulation of TRP channels);04713(Circadian entrainment);05205(Proteoglycans in cancer);05010(Alzheimer's disease);05016(Huntington's disease);05167(Kaposi's sarcoma-associated herpesvirus infection);05167(Kaposi's sarcoma-associated herpesvirus infection)","K04958","NA","inositol 1,4,5-trisphosphate receptor type 1 [Source:HGNC Symbol;Acc:HGNC:6180]",{"v":4.0176847108957,"d":"4.02"},{"v":1.35804178262893,"d":"1.36"},{"v":2.95843969035928,"d":"2.96"},{"v":1.56483648514828,"d":"1.56"},{"v":0.0517884148539734,"d":"0.05"},{"v":0.528698515802731,"d":"0.53"},"up","no"]
["MSTRG.6713","CCL4","ENST00000615863;ENST00000613947;ENST00000621626","GO:0005576(extracellular region);GO:0005515(protein binding);GO:0006955(immune response);GO:0005125(cytokine activity);GO:0005615(extracellular space);GO:0008009(chemokine activity);GO:0006935(chemotaxis);GO:0006954(inflammatory response);GO:0042802(identical protein binding);GO:0007186(G-protein coupled receptor signaling pathway);GO:0002548(monocyte chemotaxis);GO:0030593(neutrophil chemotaxis);GO:0043547(positive regulation of GTPase activity);GO:0070098(chemokine-mediated signaling pathway);GO:0070374(positive regulation of ERK1 and ERK2 cascade);GO:0071346(cellular response to interferon-gamma);GO:0071347(cellular response to interleukin-1);GO:0071356(cellular response to tumor necrosis factor);GO:0007165(signal transduction);GO:0007267(cell-cell signaling);GO:0007155(cell adhesion);GO:0006928(movement of cell or subcellular component);GO:0009615(response to virus);GO:0051928(positive regulation of calcium ion transport);GO:0009636(response to toxic substance);GO:0043922(negative regulation by host of viral transcription);GO:0031726(CCR1 chemokine receptor binding);GO:0031730(CCR5 chemokine receptor binding);GO:0050850(positive regulation of calcium-mediated signaling);GO:2000503(positive regulation of natural killer cell chemotaxis);GO:0007163(establishment or maintenance of cell polarity);GO:0035690(cellular response to drug);GO:0035690(cellular response to drug)","04064(NF-kappa B signaling pathway);04060(Cytokine-cytokine receptor interaction);04620(Toll-like receptor signaling pathway);04623(Cytosolic DNA-sensing pathway);04062(Chemokine signaling pathway);05132(Salmonella infection);05132(Salmonella infection)","K12964","NA","C-C motif chemokine ligand 4 [Source:HGNC Symbol;Acc:HGNC:10630]",{"v":4.58172592322835,"d":"4.58"},{"v":9.36159369094488,"d":"9.36"},{"v":0.489417301635306,"d":"0.49"},{"v":-1.03086299113609,"d":"-1.03"},{"v":0.05194560078873,"d":"0.05"},{"v":0.528698515802731,"d":"0.53"},"down","no"]
["ENSG00000159433","STARD9","ENST00000290607;ENST00000563872;ENST00000568493;ENST00000562139;ENST00000564158","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0003777(microtubule motor activity);GO:0005856(cytoskeleton);GO:0008152(metabolic process);GO:0008289(lipid binding);GO:0008017(microtubule binding);GO:0007018(microtubule-based movement);GO:0005814(centriole);GO:0051225(spindle assembly);GO:0015485(cholesterol binding);GO:0015485(cholesterol binding)","NA","NA","NA","StAR related lipid transfer domain containing 9 [Source:HGNC Symbol;Acc:HGNC:19162]",{"v":0.553512350864484,"d":"0.55"},{"v":0.185808865980875,"d":"0.19"},{"v":2.97893401341493,"d":"2.98"},{"v":1.57479616669808,"d":"1.57"},{"v":0.0519466959732609,"d":"0.05"},{"v":0.528698515802731,"d":"0.53"},"up","no"]
["MSTRG.3891","RPSAP54","ENST00000454001","NA","NA","NA","NA","ribosomal protein SA pseudogene 54 [Source:HGNC Symbol;Acc:HGNC:36373]",{"v":2.298923,"d":"2.30"},{"v":4.784461,"d":"4.78"},{"v":0.48049780320082,"d":"0.48"},{"v":-1.05739825976456,"d":"-1.06"},{"v":0.0519517278185497,"d":"0.05"},{"v":0.528698515802731,"d":"0.53"},"down","no"]
["MSTRG.11602","FRYL","ENST00000507711;ENST00000358350;ENST00000507873;ENST00000514783;ENST00000503238;ENST00000505437;ENST00000302806;ENST00000505759;ENST00000515684;ENST00000502520;ENST00000503339;ENST00000513401;ENST00000641795;ENST00000506685;ENST00000502925;ENST00000511343;ENST00000514617","GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0005938(cell cortex);GO:0000902(cell morphogenesis);GO:0031175(neuron projection development);GO:0090527(actin filament reorganization);GO:0030427(site of polarized growth);GO:0030427(site of polarized growth)","NA","NA","NA","FRY like transcription coactivator [Source:HGNC Symbol;Acc:HGNC:29127]",{"v":4.7047760922306,"d":"4.70"},{"v":1.59213408644898,"d":"1.59"},{"v":2.95501247807834,"d":"2.96"},{"v":1.56316422245822,"d":"1.56"},{"v":0.0519783576515574,"d":"0.05"},{"v":0.528698515802731,"d":"0.53"},"up","no"]
["MSTRG.5961","DOK4","ENST00000569548;ENST00000566936;ENST00000340099","GO:0005622(intracellular);GO:0005158(insulin receptor binding);GO:0005057(signal transducer activity, downstream of receptor);GO:0000165(MAPK cascade);GO:0007169(transmembrane receptor protein tyrosine kinase signaling pathway);GO:0007399(nervous system development);GO:0005515(protein binding);GO:0005829(cytosol);GO:0007411(axon guidance);GO:0007411(axon guidance)","NA","NA","NA","docking protein 4 [Source:HGNC Symbol;Acc:HGNC:19868]",{"v":0.986608080200501,"d":"0.99"},{"v":0.324509009607352,"d":"0.32"},{"v":3.04031028720673,"d":"3.04"},{"v":1.60421856938286,"d":"1.60"},{"v":0.0520232860449841,"d":"0.05"},{"v":0.528698515802731,"d":"0.53"},"up","no"]
["MSTRG.11180","PLXND1","ENST00000324093;ENST00000514990;ENST00000512744;ENST00000511018;ENST00000501038;ENST00000515191;ENST00000512807;ENST00000504524;ENST00000505237;ENST00000508630;ENST00000503166;ENST00000504979","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0007165(signal transduction);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0007275(multicellular organism development);GO:0017154(semaphorin receptor activity);GO:0071526(semaphorin-plexin signaling pathway);GO:0005887(integral component of plasma membrane);GO:0030027(lamellipodium);GO:0008360(regulation of cell shape);GO:0043087(regulation of GTPase activity);GO:0030334(regulation of cell migration);GO:0019904(protein domain specific binding);GO:0001525(angiogenesis);GO:0007162(negative regulation of cell adhesion);GO:0050772(positive regulation of axonogenesis);GO:0043542(endothelial cell migration);GO:0007416(synapse assembly);GO:0045765(regulation of angiogenesis);GO:0001569(branching involved in blood vessel morphogenesis);GO:0003151(outflow tract morphogenesis);GO:0003279(cardiac septum development);GO:0032092(positive regulation of protein binding);GO:0035904(aorta development);GO:0060666(dichotomous subdivision of terminal units involved in salivary gland branching);GO:0060976(coronary vasculature development);GO:0060976(coronary vasculature development)","NA","NA","NA","plexin D1 [Source:HGNC Symbol;Acc:HGNC:9107]",{"v":4.92794839001848,"d":"4.93"},{"v":1.66451765003081,"d":"1.66"},{"v":2.96058644372276,"d":"2.96"},{"v":1.56588297843861,"d":"1.57"},{"v":0.0520413555400781,"d":"0.05"},{"v":0.528698515802731,"d":"0.53"},"up","no"]
["MSTRG.3484","R3HDM2;STAC3;AC137834.1","ENST00000402412;ENST00000634871;ENST00000332782;MSTRG.3484.15;ENST00000448732;ENST00000546843;ENST00000403821;ENST00000441731;ENST00000547262;ENST00000557176;ENST00000553294;ENST00000548184;ENST00000554003;ENST00000551465;ENST00000552428;ENST00000547019;ENST00000548161;ENST00000546246;ENST00000347140;ENST00000429355;ENST00000393811","GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0035556(intracellular signal transduction);GO:0005515(protein binding);GO:0042802(identical protein binding);GO:0003009(skeletal muscle contraction);GO:0007274(neuromuscular synaptic transmission);GO:0048741(skeletal muscle fiber development);GO:0005634(nucleus)","NA","NA","NA","R3H domain containing 2 [Source:HGNC Symbol;Acc:HGNC:29167];SH3 and cysteine rich domain 3 [Source:HGNC Symbol;Acc:HGNC:28423]",{"v":7.83602322152769,"d":"7.84"},{"v":2.64895829003625,"d":"2.65"},{"v":2.95815273913598,"d":"2.96"},{"v":1.56469654544073,"d":"1.56"},{"v":0.0520822442158206,"d":"0.05"},{"v":0.528698515802731,"d":"0.53"},"up","no"]
["MSTRG.3447","RPL41","ENST00000546485;MSTRG.3447.3;ENST00000501597;ENST00000546591;ENST00000552314;ENST00000358888;ENST00000546654","GO:0006412(translation);GO:0030529(intracellular ribonucleoprotein complex);GO:0003735(structural constituent of ribosome);GO:0005840(ribosome);GO:0005829(cytosol);GO:0006413(translational initiation);GO:0003723(RNA binding);GO:0006364(rRNA processing);GO:0000184(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay);GO:0019083(viral transcription);GO:0003730(mRNA 3'-UTR binding);GO:0048027(mRNA 5'-UTR binding);GO:0006614(SRP-dependent cotranslational protein targeting to membrane);GO:0022625(cytosolic large ribosomal subunit);GO:0022625(cytosolic large ribosomal subunit)","03010(Ribosome);03010(Ribosome)","K02928","NA","ribosomal protein L41 [Source:HGNC Symbol;Acc:HGNC:10354]",{"v":279.351635869485,"d":"279.35"},{"v":566.339038202206,"d":"566.34"},{"v":0.493258661377578,"d":"0.49"},{"v":-1.01958371070636,"d":"-1.02"},{"v":0.0521931255364629,"d":"0.05"},{"v":0.529361368432265,"d":"0.53"},"down","no"]
["MSTRG.9246","CIR1","ENST00000342016;ENST00000461454;ENST00000464393;ENST00000377973;ENST00000472169","GO:0006397(mRNA processing);GO:0008380(RNA splicing);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016607(nuclear speck);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0005813(centrosome);GO:0005815(microtubule organizing center);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0019901(protein kinase binding);GO:0043234(protein complex);GO:0000118(histone deacetylase complex);GO:0045892(negative regulation of transcription, DNA-templated);GO:0003714(transcription corepressor activity);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0003705(transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding);GO:0003705(transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding)","04330(Notch signaling pathway);04330(Notch signaling pathway)","K06066","NA","corepressor interacting with RBPJ, 1 [Source:HGNC Symbol;Acc:HGNC:24217]",{"v":8.34846474001886,"d":"8.35"},{"v":16.9443864212512,"d":"16.94"},{"v":0.492697966894124,"d":"0.49"},{"v":-1.0212245764701,"d":"-1.02"},{"v":0.0523627461410801,"d":"0.05"},{"v":0.53061829924639,"d":"0.53"},"down","no"]
["MSTRG.8032","ZNF486","ENST00000335117;ENST00000597083","GO:0003676(nucleic acid binding);GO:0006355(regulation of transcription, DNA-templated);GO:0005622(intracellular);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0003674(molecular_function);GO:0008150(biological_process);GO:0070062(extracellular exosome);GO:0070062(extracellular exosome)","NA","NA","NA","zinc finger protein 486 [Source:HGNC Symbol;Acc:HGNC:20807]",{"v":0.54816943651725,"d":"0.55"},{"v":1.1391595519831,"d":"1.14"},{"v":0.481205144233722,"d":"0.48"},{"v":-1.05527602942904,"d":"-1.06"},{"v":0.0524437862704036,"d":"0.05"},{"v":0.530976190024584,"d":"0.53"},"down","no"]
["MSTRG.3688","SSH1","ENST00000326495;ENST00000546812;ENST00000546433;ENST00000547381;ENST00000548522;ENST00000326470;ENST00000547862;ENST00000551165","GO:0005737(cytoplasm);GO:0016787(hydrolase activity);GO:0003779(actin binding);GO:0004725(protein tyrosine phosphatase activity);GO:0008138(protein tyrosine/serine/threonine phosphatase activity);GO:0016791(phosphatase activity);GO:0006470(protein dephosphorylation);GO:0016311(dephosphorylation);GO:0035335(peptidyl-tyrosine dephosphorylation);GO:0005886(plasma membrane);GO:0004721(phosphoprotein phosphatase activity);GO:0030036(actin cytoskeleton organization);GO:0005856(cytoskeleton);GO:0042995(cell projection);GO:0005515(protein binding);GO:0030496(midbody);GO:0030027(lamellipodium);GO:0032154(cleavage furrow);GO:0050770(regulation of axonogenesis);GO:0000902(cell morphogenesis);GO:0071318(cellular response to ATP);GO:0010591(regulation of lamellipodium assembly);GO:0008064(regulation of actin polymerization or depolymerization);GO:0032268(regulation of cellular protein metabolic process);GO:0031915(positive regulation of synaptic plasticity);GO:0098976(excitatory chemical synaptic transmission);GO:1901216(positive regulation of neuron death);GO:1904719(positive regulation of AMPA glutamate receptor clustering);GO:1904754(positive regulation of vascular associated smooth muscle cell migration);GO:2000463(positive regulation of excitatory postsynaptic potential);GO:0005829(cytosol);GO:0030426(growth cone);GO:0031252(cell leading edge);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016021(integral component of membrane)","04810(Regulation of actin cytoskeleton);04360(Axon guidance);04360(Axon guidance)","K05766","EC:3.1.3.16;EC:3.1.3.48","slingshot protein phosphatase 1 [Source:HGNC Symbol;Acc:HGNC:30579]",{"v":4.28658025690778,"d":"4.29"},{"v":1.45551383654439,"d":"1.46"},{"v":2.94506321361037,"d":"2.95"},{"v":1.55829860077337,"d":"1.56"},{"v":0.0525960144162518,"d":"0.05"},{"v":0.531208838000641,"d":"0.53"},"up","no"]
["MSTRG.7581","MED16","ENST00000395808;ENST00000325464;ENST00000312090;ENST00000607471;ENST00000621073;ENST00000586017;ENST00000592373;ENST00000606248;ENST00000589119","GO:0005634(nucleus);GO:0016020(membrane);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003824(catalytic activity);GO:0005515(protein binding);GO:0045893(positive regulation of transcription, DNA-templated);GO:0006367(transcription initiation from RNA polymerase II promoter);GO:2000273(positive regulation of receptor activity);GO:0005654(nucleoplasm);GO:0004872(receptor activity);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0003713(transcription coactivator activity);GO:0006366(transcription from RNA polymerase II promoter);GO:0003712(transcription cofactor activity);GO:0030518(intracellular steroid hormone receptor signaling pathway);GO:0030521(androgen receptor signaling pathway);GO:0042809(vitamin D receptor binding);GO:0016592(mediator complex);GO:0046966(thyroid hormone receptor binding);GO:0030375(thyroid hormone receptor coactivator activity);GO:0030375(thyroid hormone receptor coactivator activity)","04919(Thyroid hormone signaling pathway);04919(Thyroid hormone signaling pathway)","K15159","NA","mediator complex subunit 16 [Source:HGNC Symbol;Acc:HGNC:17556]",{"v":9.31883402486973,"d":"9.32"},{"v":3.16191573851255,"d":"3.16"},{"v":2.94721137295504,"d":"2.95"},{"v":1.55935053374947,"d":"1.56"},{"v":0.0526221953424339,"d":"0.05"},{"v":0.531208838000641,"d":"0.53"},"up","no"]
["MSTRG.14910","KIAA1958","ENST00000337530;ENST00000374244","GO:0005515(protein binding);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0005737(cytoplasm);GO:0000981(RNA polymerase II transcription factor activity, sequence-specific DNA binding);GO:0005654(nucleoplasm);GO:0003677(DNA binding);GO:0003677(DNA binding)","NA","NA","NA","KIAA1958 [Source:HGNC Symbol;Acc:HGNC:23427]",{"v":0.339143705922708,"d":"0.34"},{"v":0.112138643494169,"d":"0.11"},{"v":3.02432502619262,"d":"3.02"},{"v":1.59661319527265,"d":"1.60"},{"v":0.0527279200799693,"d":"0.05"},{"v":0.531208838000641,"d":"0.53"},"up","no"]
["ENSG00000184371","CSF1","ENST00000329608;ENST00000527192;ENST00000420111;ENST00000369802","GO:0016021(integral component of membrane);GO:0008083(growth factor activity);GO:0005125(cytokine activity);GO:0005615(extracellular space);GO:0010628(positive regulation of gene expression);GO:0048471(perinuclear region of cytoplasm);GO:0030335(positive regulation of cell migration);GO:0016020(membrane);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0030154(cell differentiation);GO:0002376(immune system process);GO:0045087(innate immune response);GO:0006954(inflammatory response);GO:0070062(extracellular exosome);GO:0044267(cellular protein metabolic process);GO:0043687(post-translational protein modification);GO:0008283(cell proliferation);GO:0008284(positive regulation of cell proliferation);GO:0042803(protein homodimerization activity);GO:0005788(endoplasmic reticulum lumen);GO:0030097(hemopoiesis);GO:0001954(positive regulation of cell-matrix adhesion);GO:0045860(positive regulation of protein kinase activity);GO:0042117(monocyte activation);GO:0030316(osteoclast differentiation);GO:0045672(positive regulation of osteoclast differentiation);GO:0010744(positive regulation of macrophage derived foam cell differentiation);GO:0032270(positive regulation of cellular protein metabolic process);GO:0045651(positive regulation of macrophage differentiation);GO:0007169(transmembrane receptor protein tyrosine kinase signaling pathway);GO:0030225(macrophage differentiation);GO:1990682(CSF1-CSF1R complex);GO:0010759(positive regulation of macrophage chemotaxis);GO:0005157(macrophage colony-stimulating factor receptor binding);GO:0002158(osteoclast proliferation);GO:0003006(developmental process involved in reproduction);GO:0010743(regulation of macrophage derived foam cell differentiation);GO:0030278(regulation of ossification);GO:0032946(positive regulation of mononuclear cell proliferation);GO:0038145(macrophage colony-stimulating factor signaling pathway);GO:0040018(positive regulation of multicellular organism growth);GO:0042488(positive regulation of odontogenesis of dentin-containing tooth);GO:0045657(positive regulation of monocyte differentiation);GO:0046579(positive regulation of Ras protein signal transduction);GO:0048873(homeostasis of number of cells within a tissue);GO:0060444(branching involved in mammary gland duct morphogenesis);GO:0060611(mammary gland fat development);GO:0060763(mammary duct terminal end bud growth);GO:1902228(positive regulation of macrophage colony-stimulating factor signaling pathway);GO:1904141(positive regulation of microglial cell migration);GO:1904141(positive regulation of microglial cell migration)","04014(Ras signaling pathway);04015(Rap1 signaling pathway);04010(MAPK signaling pathway);04668(TNF signaling pathway);04151(PI3K-Akt signaling pathway);04060(Cytokine-cytokine receptor interaction);04640(Hematopoietic cell lineage);04380(Osteoclast differentiation);05323(Rheumatoid arthritis);05323(Rheumatoid arthritis)","K05453","NA","colony stimulating factor 1 [Source:HGNC Symbol;Acc:HGNC:2432]",{"v":1.84317883628645,"d":"1.84"},{"v":0.617047852159468,"d":"0.62"},{"v":2.98709221632637,"d":"2.99"},{"v":1.5787417766454,"d":"1.58"},{"v":0.0527701497452228,"d":"0.05"},{"v":0.531208838000641,"d":"0.53"},"up","no"]
["MSTRG.3105","SLC2A3","ENST00000075120;ENST00000479059;ENST00000490763;ENST00000541671;ENST00000544291;ENST00000544936;ENST00000495813;ENST00000469295;ENST00000476634;ENST00000486749","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005215(transporter activity);GO:0055085(transmembrane transport);GO:0005886(plasma membrane);GO:0022857(transmembrane transporter activity);GO:0022891(substrate-specific transmembrane transporter activity);GO:0008643(carbohydrate transport);GO:0005887(integral component of plasma membrane);GO:0005355(glucose transmembrane transporter activity);GO:0070062(extracellular exosome);GO:0043312(neutrophil degranulation);GO:0035579(specific granule membrane);GO:0070821(tertiary granule membrane);GO:0005975(carbohydrate metabolic process);GO:0030667(secretory granule membrane);GO:0101003(ficolin-1-rich granule membrane);GO:0055056(D-glucose transmembrane transporter activity);GO:0019852(L-ascorbic acid metabolic process);GO:0015758(glucose transport);GO:0005536(glucose binding);GO:0033300(dehydroascorbic acid transporter activity);GO:1904659(glucose transmembrane transport);GO:0070837(dehydroascorbic acid transport);GO:0070837(dehydroascorbic acid transport)","NA","NA","NA","solute carrier family 2 member 3 [Source:HGNC Symbol;Acc:HGNC:11007]",{"v":16.2021538239974,"d":"16.20"},{"v":32.7905001769768,"d":"32.79"},{"v":0.494111213203555,"d":"0.49"},{"v":-1.01709229866559,"d":"-1.02"},{"v":0.0528125991042425,"d":"0.05"},{"v":0.531208838000641,"d":"0.53"},"down","no"]
["ENSG00000232442","MHENCR","ENST00000449500;ENST00000411579","NA","NA","NA","NA","melanoma highly expressed competing endogenous lncRNA for miR-425 and miR-489 [Source:HGNC Symbol;Acc:HGNC:53110]",{"v":2.183151,"d":"2.18"},{"v":4.54932277902622,"d":"4.55"},{"v":0.479884832543648,"d":"0.48"},{"v":-1.05923987958251,"d":"-1.06"},{"v":0.0528282311692238,"d":"0.05"},{"v":0.531208838000641,"d":"0.53"},"down","no"]
["ENSG00000197077","KIAA1671","ENST00000401395;ENST00000358431;ENST00000637069;ENST00000406486;ENST00000494730","NA","NA","NA","NA","KIAA1671 [Source:HGNC Symbol;Acc:HGNC:29345]",{"v":0.68547469286453,"d":"0.69"},{"v":0.230626705395705,"d":"0.23"},{"v":2.97222601211081,"d":"2.97"},{"v":1.57154382454201,"d":"1.57"},{"v":0.052832308644518,"d":"0.05"},{"v":0.531208838000641,"d":"0.53"},"up","no"]
["MSTRG.775","KCNA3;AL365361.1","MSTRG.775.2;ENST00000566942","NA","NA","NA","NA",null,{"v":9.05967096456166,"d":"9.06"},{"v":3.07990485546513,"d":"3.08"},{"v":2.94154247930281,"d":"2.94"},{"v":1.55657287060002,"d":"1.56"},{"v":0.0528327054069354,"d":"0.05"},{"v":0.531208838000641,"d":"0.53"},"up","no"]
["ENSG00000132466","ANKRD17","ENST00000330838;ENST00000558247;ENST00000358602;ENST00000510127;ENST00000561029;ENST00000559367;ENST00000509867;ENST00000639793;ENST00000514252;ENST00000560507","GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0031965(nuclear membrane);GO:0002376(immune system process);GO:0045087(innate immune response);GO:0042742(defense response to bacterium);GO:0005515(protein binding);GO:0003682(chromatin binding);GO:0016032(viral process);GO:0043123(positive regulation of I-kappaB kinase/NF-kappaB signaling);GO:0000785(chromatin);GO:1900087(positive regulation of G1/S transition of mitotic cell cycle);GO:0045787(positive regulation of cell cycle);GO:0001955(blood vessel maturation);GO:0006275(regulation of DNA replication);GO:0051151(negative regulation of smooth muscle cell differentiation);GO:1900245(positive regulation of MDA-5 signaling pathway);GO:1900246(positive regulation of RIG-I signaling pathway);GO:1900246(positive regulation of RIG-I signaling pathway)","NA","NA","NA","ankyrin repeat domain 17 [Source:HGNC Symbol;Acc:HGNC:23575]",{"v":5.73328654725129,"d":"5.73"},{"v":1.94794931315396,"d":"1.95"},{"v":2.94324216165996,"d":"2.94"},{"v":1.5574062480388,"d":"1.56"},{"v":0.0529970930591692,"d":"0.05"},{"v":0.532400728110841,"d":"0.53"},"up","no"]
["MSTRG.1104","DUSP23","ENST00000368108;ENST00000368107;ENST00000368109","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005654(nucleoplasm);GO:0016787(hydrolase activity);GO:0004725(protein tyrosine phosphatase activity);GO:0008138(protein tyrosine/serine/threonine phosphatase activity);GO:0016791(phosphatase activity);GO:0006470(protein dephosphorylation);GO:0016311(dephosphorylation);GO:0035335(peptidyl-tyrosine dephosphorylation);GO:0005829(cytosol);GO:0004721(phosphoprotein phosphatase activity);GO:0005515(protein binding);GO:0070062(extracellular exosome);GO:0004722(protein serine/threonine phosphatase activity);GO:0004722(protein serine/threonine phosphatase activity)","NA","NA","NA","dual specificity phosphatase 23 [Source:HGNC Symbol;Acc:HGNC:21480]",{"v":7.12862012727273,"d":"7.13"},{"v":14.517044409697,"d":"14.52"},{"v":0.491051754481856,"d":"0.49"},{"v":-1.02605300924869,"d":"-1.03"},{"v":0.053246757994226,"d":"0.05"},{"v":0.534446500075149,"d":"0.53"},"down","no"]
["MSTRG.7974","MAP1S","ENST00000324096;ENST00000594212;ENST00000598769;ENST00000598756;ENST00000600608;ENST00000594365;ENST00000596637;ENST00000601097;ENST00000544059;ENST00000601544;ENST00000597067;ENST00000599494;ENST00000593593","GO:0051015(actin filament binding);GO:0006915(apoptotic process);GO:0008017(microtubule binding);GO:0000226(microtubule cytoskeleton organization);GO:0005874(microtubule);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005730(nucleolus);GO:0005829(cytosol);GO:0003677(DNA binding);GO:0030054(cell junction);GO:0005856(cytoskeleton);GO:0042995(cell projection);GO:0005515(protein binding);GO:0045202(synapse);GO:0005819(spindle);GO:0048471(perinuclear region of cytoplasm);GO:0007399(nervous system development);GO:0015631(tubulin binding);GO:0001578(microtubule bundle formation);GO:0007420(brain development);GO:0030425(dendrite);GO:0048487(beta-tubulin binding);GO:0047497(mitochondrion transport along microtubule);GO:0006914(autophagy);GO:0042802(identical protein binding);GO:0010848(regulation of chromatin disassembly);GO:0048812(neuron projection morphogenesis);GO:0015630(microtubule cytoskeleton);GO:0043025(neuronal cell body);GO:0043025(neuronal cell body)","NA","NA","NA","microtubule associated protein 1S [Source:HGNC Symbol;Acc:HGNC:15715]",{"v":5.88248384325397,"d":"5.88"},{"v":1.99234048015873,"d":"1.99"},{"v":2.95254947727876,"d":"2.95"},{"v":1.56196123575338,"d":"1.56"},{"v":0.0532985227390371,"d":"0.05"},{"v":0.534504097209359,"d":"0.53"},"up","no"]
["ENSG00000187800","PEAR1","ENST00000338302;ENST00000292357;ENST00000444016;ENST00000469390;ENST00000465101;ENST00000455314","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005886(plasma membrane);GO:0043654(recognition of apoptotic cell);GO:0045746(negative regulation of Notch signaling pathway);GO:0001891(phagocytic cup);GO:0001891(phagocytic cup)","NA","NA","NA","platelet endothelial aggregation receptor 1 [Source:HGNC Symbol;Acc:HGNC:33631]",{"v":2.30325458987342,"d":"2.30"},{"v":0.775195222061483,"d":"0.78"},{"v":2.97119296446172,"d":"2.97"},{"v":1.57104230420793,"d":"1.57"},{"v":0.0534700338383261,"d":"0.05"},{"v":0.535256385960602,"d":"0.54"},"up","no"]
["MSTRG.10031","DSCR3","ENST00000309117;ENST00000476950;ENST00000399001;ENST00000462467;ENST00000488368;ENST00000498789;ENST00000475009;ENST00000399000;ENST00000480452;ENST00000495858;ENST00000497493","GO:0005634(nucleus);GO:0006886(intracellular protein transport);GO:0003674(molecular_function);GO:0008150(biological_process);GO:0005768(endosome);GO:0008565(protein transporter activity);GO:0008565(protein transporter activity)","NA","NA","NA","DSCR3 arrestin fold containing [Source:HGNC Symbol;Acc:HGNC:3044]",{"v":1.90225208665735,"d":"1.90"},{"v":3.84964062111601,"d":"3.85"},{"v":0.494137576433274,"d":"0.49"},{"v":-1.01701532594134,"d":"-1.02"},{"v":0.053478941352457,"d":"0.05"},{"v":0.535256385960602,"d":"0.54"},"down","no"]
["MSTRG.6445","GAS7","ENST00000432992;ENST00000585266;ENST00000580811;ENST00000542249;ENST00000437099;ENST00000580043;ENST00000578599;ENST00000323816;ENST00000579158;ENST00000580865;ENST00000583882;ENST00000584146;ENST00000578456;ENST00000584389;ENST00000578655;MSTRG.6445.5","GO:0005737(cytoplasm);GO:0005515(protein binding);GO:0007275(multicellular organism development);GO:0007399(nervous system development);GO:0030154(cell differentiation);GO:0006355(regulation of transcription, DNA-templated);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0007050(cell cycle arrest);GO:0007050(cell cycle arrest)","NA","NA","NA","growth arrest specific 7 [Source:HGNC Symbol;Acc:HGNC:4169]",{"v":3.67536594849234,"d":"3.68"},{"v":1.24656387533366,"d":"1.25"},{"v":2.94839760819202,"d":"2.95"},{"v":1.55993109318693,"d":"1.56"},{"v":0.0535118112546507,"d":"0.05"},{"v":0.535256385960602,"d":"0.54"},"up","no"]
["MSTRG.4367","LRR1","ENST00000298288;ENST00000554869;ENST00000318317","GO:0016567(protein ubiquitination);GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0005886(plasma membrane);GO:0005829(cytosol);GO:0007165(signal transduction);GO:0043687(post-translational protein modification);GO:0016853(isomerase activity);GO:0016853(isomerase activity)","NA","NA","NA","leucine rich repeat protein 1 [Source:HGNC Symbol;Acc:HGNC:19742]",{"v":0.709084418437162,"d":"0.71"},{"v":1.47042067518905,"d":"1.47"},{"v":0.482232350511527,"d":"0.48"},{"v":-1.05219965764036,"d":"-1.05"},{"v":0.0535623988470766,"d":"0.05"},{"v":0.535301323417471,"d":"0.54"},"down","no"]
["MSTRG.2630","CHKA","ENST00000265689;ENST00000530730;ENST00000533910;ENST00000533728;ENST00000525155;ENST00000528235","GO:0005737(cytoplasm);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0006629(lipid metabolic process);GO:0006646(phosphatidylethanolamine biosynthetic process);GO:0008654(phospholipid biosynthetic process);GO:0007165(signal transduction);GO:0005829(cytosol);GO:0006656(phosphatidylcholine biosynthetic process);GO:0004871(signal transducer activity);GO:0008144(drug binding);GO:0006869(lipid transport);GO:0004103(choline kinase activity);GO:0004104(cholinesterase activity);GO:0004305(ethanolamine kinase activity);GO:0033265(choline binding);GO:0042803(protein homodimerization activity);GO:0006580(ethanolamine metabolic process);GO:0006657(CDP-choline pathway);GO:0009636(response to toxic substance);GO:0019695(choline metabolic process);GO:1904681(response to 3-methylcholanthrene);GO:1904681(response to 3-methylcholanthrene)","00564(Glycerophospholipid metabolism);05231(Choline metabolism in cancer);05231(Choline metabolism in cancer)","K14156","EC:2.7.1.32;EC:2.7.1.82","choline kinase alpha [Source:HGNC Symbol;Acc:HGNC:1937]",{"v":0.394257017539335,"d":"0.39"},{"v":0.833837106009801,"d":"0.83"},{"v":0.472822586927069,"d":"0.47"},{"v":-1.08062913959752,"d":"-1.08"},{"v":0.0536338158394643,"d":"0.05"},{"v":0.535347534705306,"d":"0.54"},"down","no"]
["ENSG00000116991","SIPA1L2","ENST00000366630;ENST00000486472;ENST00000494056","GO:0043547(positive regulation of GTPase activity);GO:0005096(GTPase activator activity);GO:0051056(regulation of small GTPase mediated signal transduction);GO:0008150(biological_process);GO:0005575(cellular_component);GO:0005575(cellular_component)","04015(Rap1 signaling pathway);04015(Rap1 signaling pathway)","NA","NA","signal induced proliferation associated 1 like 2 [Source:HGNC Symbol;Acc:HGNC:23800]",{"v":4.25386932194739,"d":"4.25"},{"v":1.44852736042403,"d":"1.45"},{"v":2.93668551811279,"d":"2.94"},{"v":1.55418877953709,"d":"1.55"},{"v":0.0536975879574068,"d":"0.05"},{"v":0.535347534705306,"d":"0.54"},"up","no"]
["MSTRG.4292","KHNYN","MSTRG.4292.5;ENST00000556842;ENST00000553935;ENST00000251343;ENST00000556255;ENST00000554268;ENST00000556510","GO:0003674(molecular_function);GO:0008150(biological_process);GO:0005575(cellular_component);GO:0003723(RNA binding);GO:0003723(RNA binding)","NA","NA","NA","KH and NYN domain containing [Source:HGNC Symbol;Acc:HGNC:20166]",{"v":6.17593417766687,"d":"6.18"},{"v":2.10300422694947,"d":"2.10"},{"v":2.93671981184052,"d":"2.94"},{"v":1.55420562679627,"d":"1.55"},{"v":0.0537053197220082,"d":"0.05"},{"v":0.535347534705306,"d":"0.54"},"up","no"]
["MSTRG.9101","MZT2B;AC018804.1","ENST00000281871;ENST00000491178;ENST00000485869;ENST00000480182;ENST00000425361;MSTRG.9101.3;ENST00000455239;ENST00000409255;ENST00000430381","GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0005813(centrosome);GO:0005815(microtubule organizing center);GO:0005737(cytoplasm);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0005819(spindle);GO:0008274(gamma-tubulin ring complex);GO:0008274(gamma-tubulin ring complex)","NA","NA","NA","mitotic spindle organizing protein 2B [Source:HGNC Symbol;Acc:HGNC:25886]",{"v":6.20124506576243,"d":"6.20"},{"v":12.5730469601315,"d":"12.57"},{"v":0.493217362937263,"d":"0.49"},{"v":-1.01970450645527,"d":"-1.02"},{"v":0.0538543969705489,"d":"0.05"},{"v":0.53611509261579,"d":"0.54"},"down","no"]
["MSTRG.3072","ATN1","ENST00000396684;ENST00000356654;MSTRG.3072.3","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005654(nucleoplasm);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0005515(protein binding);GO:0048471(perinuclear region of cytoplasm);GO:0030054(cell junction);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0003714(transcription corepressor activity);GO:0019904(protein domain specific binding);GO:0007417(central nervous system development);GO:0016363(nuclear matrix);GO:0051402(neuron apoptotic process);GO:0051402(neuron apoptotic process)","NA","NA","NA","atrophin 1 [Source:HGNC Symbol;Acc:HGNC:3033]",{"v":2.36589109649123,"d":"2.37"},{"v":0.799148690476191,"d":"0.80"},{"v":2.96051426309847,"d":"2.96"},{"v":1.56584780436073,"d":"1.57"},{"v":0.0539011204206721,"d":"0.05"},{"v":0.53611509261579,"d":"0.54"},"up","no"]
["ENSG00000156253","RWDD2B","ENST00000286777;ENST00000486719;ENST00000493196;ENST00000481411;ENST00000466746;ENST00000472184","GO:0005515(protein binding);GO:0003674(molecular_function);GO:0008150(biological_process);GO:0005575(cellular_component);GO:0005575(cellular_component)","NA","NA","NA","RWD domain containing 2B [Source:HGNC Symbol;Acc:HGNC:1302]",{"v":0.483879582032401,"d":"0.48"},{"v":1.0208528910162,"d":"1.02"},{"v":0.47399540745849,"d":"0.47"},{"v":-1.07705501396838,"d":"-1.08"},{"v":0.0540203205165008,"d":"0.05"},{"v":0.53611509261579,"d":"0.54"},"down","no"]
["MSTRG.2058","NLRP6","ENST00000534750;ENST00000312165","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0005886(plasma membrane);GO:0002376(immune system process);GO:0045087(innate immune response);GO:0006954(inflammatory response);GO:0007186(G-protein coupled receptor signaling pathway);GO:0005000(vasopressin receptor activity);GO:0031965(nuclear membrane);GO:0050727(regulation of inflammatory response);GO:0061702(inflammasome complex);GO:0002862(negative regulation of inflammatory response to antigenic stimulus);GO:0009617(response to bacterium);GO:0010506(regulation of autophagy);GO:0034122(negative regulation of toll-like receptor signaling pathway);GO:0042060(wound healing);GO:0043124(negative regulation of I-kappaB kinase/NF-kappaB signaling);GO:0043409(negative regulation of MAPK cascade);GO:0050777(negative regulation of immune response);GO:0070255(regulation of mucus secretion);GO:0070373(negative regulation of ERK1 and ERK2 cascade);GO:0070373(negative regulation of ERK1 and ERK2 cascade)","04621(NOD-like receptor signaling pathway);04621(NOD-like receptor signaling pathway)","K20863","NA","NLR family pyrin domain containing 6 [Source:HGNC Symbol;Acc:HGNC:22944]",{"v":7.79745287090739,"d":"7.80"},{"v":2.64912640037418,"d":"2.65"},{"v":2.9434053693346,"d":"2.94"},{"v":1.5574862456611,"d":"1.56"},{"v":0.054041491393944,"d":"0.05"},{"v":0.53611509261579,"d":"0.54"},"up","no"]
["MSTRG.13901","CBLL1","ENST00000440859;ENST00000415884;ENST00000432748;ENST00000222597;ENST00000493361;ENST00000479443;ENST00000487517","GO:0005634(nucleus);GO:0016607(nuclear speck);GO:0046872(metal ion binding);GO:0016740(transferase activity);GO:0016567(protein ubiquitination);GO:0005654(nucleoplasm);GO:0061630(ubiquitin protein ligase activity);GO:0005515(protein binding);GO:0005829(cytosol);GO:0030335(positive regulation of cell migration);GO:0004842(ubiquitin-protein transferase activity);GO:0045807(positive regulation of endocytosis);GO:0007162(negative regulation of cell adhesion);GO:0000151(ubiquitin ligase complex);GO:0016337(single organismal cell-cell adhesion);GO:0035635(entry of bacterium into host cell);GO:0042802(identical protein binding);GO:0030155(regulation of cell adhesion);GO:0030155(regulation of cell adhesion)","NA","NA","NA","Cbl proto-oncogene like 1 [Source:HGNC Symbol;Acc:HGNC:21225]",{"v":3.09700964221857,"d":"3.10"},{"v":1.05306139025725,"d":"1.05"},{"v":2.94095830582299,"d":"2.94"},{"v":1.55628633117881,"d":"1.56"},{"v":0.0540939687557727,"d":"0.05"},{"v":0.53611509261579,"d":"0.54"},"up","no"]
["MSTRG.8818","DYSF","ENST00000409582;ENST00000409651;ENST00000409762;ENST00000258104;ENST00000413539;ENST00000410041;ENST00000429174;ENST00000410020;ENST00000409366;ENST00000479049;ENST00000468173;ENST00000394120;ENST00000493767;ENST00000472873;ENST00000409744;ENST00000475076;ENST00000494501;ENST00000461565;ENST00000487180","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0046872(metal ion binding);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0005815(microtubule organizing center);GO:0030659(cytoplasmic vesicle membrane);GO:0031410(cytoplasmic vesicle);GO:0005544(calcium-dependent phospholipid binding);GO:0005509(calcium ion binding);GO:0008289(lipid binding);GO:0005768(endosome);GO:0070062(extracellular exosome);GO:0042383(sarcolemma);GO:0005769(early endosome);GO:0005770(late endosome);GO:0030315(T-tubule);GO:0005543(phospholipid binding);GO:0006936(muscle contraction);GO:0030139(endocytic vesicle);GO:0001778(plasma membrane repair);GO:0006906(vesicle fusion);GO:0030027(lamellipodium);GO:0030027(lamellipodium)","NA","NA","NA","dysferlin [Source:HGNC Symbol;Acc:HGNC:3097]",{"v":23.7756592198903,"d":"23.78"},{"v":8.12809869806821,"d":"8.13"},{"v":2.92511940406691,"d":"2.93"},{"v":1.54849551705133,"d":"1.55"},{"v":0.0541540199950106,"d":"0.05"},{"v":0.53611509261579,"d":"0.54"},"up","no"]
["ENSG00000165671","NSD1","ENST00000354179;ENST00000439151;ENST00000513736;ENST00000375350;ENST00000602285;ENST00000505395;ENST00000512992;ENST00000508029;ENST00000347982;ENST00000511258","GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0008168(methyltransferase activity);GO:0016740(transferase activity);GO:0032259(methylation);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0016569(covalent chromatin modification);GO:0005694(chromosome);GO:0008270(zinc ion binding);GO:0018024(histone-lysine N-methyltransferase activity);GO:0046975(histone methyltransferase activity (H3-K36 specific));GO:0045893(positive regulation of transcription, DNA-templated);GO:0034968(histone lysine methylation);GO:0042799(histone methyltransferase activity (H4-K20 specific));GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0003714(transcription corepressor activity);GO:0005654(nucleoplasm);GO:0030331(estrogen receptor binding);GO:0042974(retinoic acid receptor binding);GO:0003682(chromatin binding);GO:0003712(transcription cofactor activity);GO:0050681(androgen receptor binding);GO:0046966(thyroid hormone receptor binding);GO:0046965(retinoid X receptor binding);GO:0016571(histone methylation);GO:0000979(RNA polymerase II core promoter sequence-specific DNA binding);GO:0000414(regulation of histone H3-K36 methylation);GO:0010452(histone H3-K36 methylation);GO:0033135(regulation of peptidyl-serine phosphorylation);GO:0034770(histone H4-K20 methylation);GO:1903025(regulation of RNA polymerase II regulatory region sequence-specific DNA binding);GO:1903025(regulation of RNA polymerase II regulatory region sequence-specific DNA binding)","00310(Lysine degradation);00310(Lysine degradation)","K15588","EC:2.1.1.43","nuclear receptor binding SET domain protein 1 [Source:HGNC Symbol;Acc:HGNC:14234]",{"v":6.38300538656344,"d":"6.38"},{"v":2.17857319091983,"d":"2.18"},{"v":2.92990174173053,"d":"2.93"},{"v":1.55085228270381,"d":"1.55"},{"v":0.0541542640820054,"d":"0.05"},{"v":0.53611509261579,"d":"0.54"},"up","no"]
["MSTRG.5844","DCTPP1","ENST00000319285","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0016787(hydrolase activity);GO:0005829(cytosol);GO:0005739(mitochondrion);GO:0005515(protein binding);GO:0000287(magnesium ion binding);GO:0042802(identical protein binding);GO:0047429(nucleoside-triphosphate diphosphatase activity);GO:0009143(nucleoside triphosphate catabolic process);GO:0042262(DNA protection);GO:0016462(pyrophosphatase activity);GO:0032556(pyrimidine deoxyribonucleotide binding);GO:0047840(dCTP diphosphatase activity);GO:0006253(dCTP catabolic process);GO:0051289(protein homotetramerization)","00240(Pyrimidine metabolism)","K16904","EC:3.6.1.12","dCTP pyrophosphatase 1 [Source:HGNC Symbol;Acc:HGNC:28777]",{"v":3.46324152435168,"d":"3.46"},{"v":7.04036401897533,"d":"7.04"},{"v":0.491912281100449,"d":"0.49"},{"v":-1.02352702099803,"d":"-1.02"},{"v":0.0541910886714291,"d":"0.05"},{"v":0.53611509261579,"d":"0.54"},"down","no"]
["ENSG00000008324","SS18L2","ENST00000011691;ENST00000474941","GO:0003713(transcription coactivator activity);GO:1903506(regulation of nucleic acid-templated transcription);GO:1903506(regulation of nucleic acid-templated transcription)","NA","NA","NA","SS18 like 2 [Source:HGNC Symbol;Acc:HGNC:15593]",{"v":2.40103829506934,"d":"2.40"},{"v":0.791806912942989,"d":"0.79"},{"v":3.03235328692087,"d":"3.03"},{"v":1.60043784572435,"d":"1.60"},{"v":0.0542467458627579,"d":"0.05"},{"v":0.53611509261579,"d":"0.54"},"up","no"]
["MSTRG.7083","USP32","MSTRG.7083.1;ENST00000300896;ENST00000586238;ENST00000593071;ENST00000588898;ENST00000589761;ENST00000585720;ENST00000589552;ENST00000590133;ENST00000587651;ENST00000393003;ENST00000586881","GO:0016020(membrane);GO:0005794(Golgi apparatus);GO:0046872(metal ion binding);GO:0005829(cytosol);GO:0004843(thiol-dependent ubiquitin-specific protease activity);GO:0016579(protein deubiquitination);GO:0016787(hydrolase activity);GO:0005509(calcium ion binding);GO:0005515(protein binding);GO:0008233(peptidase activity);GO:0008234(cysteine-type peptidase activity);GO:0006508(proteolysis);GO:0006511(ubiquitin-dependent protein catabolic process);GO:0036459(thiol-dependent ubiquitinyl hydrolase activity);GO:0036459(thiol-dependent ubiquitinyl hydrolase activity)","NA","NA","NA","ubiquitin specific peptidase 32 [Source:HGNC Symbol;Acc:HGNC:19143]",{"v":14.6155940744085,"d":"14.62"},{"v":4.99621592258198,"d":"5.00"},{"v":2.92533275200311,"d":"2.93"},{"v":1.54860073832363,"d":"1.55"},{"v":0.0542838972701019,"d":"0.05"},{"v":0.53611509261579,"d":"0.54"},"up","no"]
["MSTRG.10504","MKL1","ENST00000407029;ENST00000355630;MSTRG.10504.7;ENST00000620651;ENST00000422851;ENST00000402630;ENST00000618417;ENST00000477468;ENST00000396617;ENST00000618196;ENST00000463769;ENST00000402042","GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0005737(cytoplasm);GO:0005634(nucleus);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0003713(transcription coactivator activity);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003779(actin binding);GO:0005515(protein binding);GO:0003785(actin monomer binding);GO:0010735(positive regulation of transcription via serum response element binding);GO:0001105(RNA polymerase II transcription coactivator activity);GO:0051145(smooth muscle cell differentiation);GO:0043522(leucine zipper domain binding);GO:0043086(negative regulation of catalytic activity);GO:0004864(protein phosphatase inhibitor activity);GO:0000976(transcription regulatory region sequence-specific DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0001764(neuron migration);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0030036(actin cytoskeleton organization);GO:0030900(forebrain development);GO:0031175(neuron projection development);GO:0043154(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process);GO:0045893(positive regulation of transcription, DNA-templated);GO:2001234(negative regulation of apoptotic signaling pathway);GO:2001234(negative regulation of apoptotic signaling pathway)","NA","NA","NA","megakaryoblastic leukemia (translocation) 1 [Source:HGNC Symbol;Acc:HGNC:14334]",{"v":7.62593623977583,"d":"7.63"},{"v":2.60243038003635,"d":"2.60"},{"v":2.9303132557457,"d":"2.93"},{"v":1.55105489958056,"d":"1.55"},{"v":0.0543038549504324,"d":"0.05"},{"v":0.53611509261579,"d":"0.54"},"up","no"]
["MSTRG.4530","FAM161B;AC005480.1","ENST00000286544;ENST00000554009;ENST00000555916","NA","NA","NA","NA","family with sequence similarity 161 member B [Source:HGNC Symbol;Acc:HGNC:19854]",{"v":0.533280039284054,"d":"0.53"},{"v":0.178867033007903,"d":"0.18"},{"v":2.98143280131723,"d":"2.98"},{"v":1.57600582014329,"d":"1.58"},{"v":0.0544549954643816,"d":"0.05"},{"v":0.53611509261579,"d":"0.54"},"up","no"]
["ENSG00000124635","HIST1H2BJ","ENST00000607124","GO:0005634(nucleus);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0003677(DNA binding);GO:0046982(protein heterodimerization activity);GO:0006334(nucleosome assembly);GO:0000786(nucleosome);GO:0005694(chromosome);GO:0005886(plasma membrane);GO:0005615(extracellular space);GO:0042742(defense response to bacterium);GO:0005515(protein binding);GO:0016567(protein ubiquitination);GO:0050829(defense response to Gram-negative bacterium);GO:0002227(innate immune response in mucosa);GO:0019731(antibacterial humoral response);GO:0050830(defense response to Gram-positive bacterium);GO:0061844(antimicrobial humoral immune response mediated by antimicrobial peptide);GO:0001530(lipopolysaccharide binding);GO:0031640(killing of cells of other organism);GO:0010804(negative regulation of tumor necrosis factor-mediated signaling pathway)","05203(Viral carcinogenesis);05322(Systemic lupus erythematosus);05034(Alcoholism)","NA","NA","histone cluster 1 H2B family member j [Source:HGNC Symbol;Acc:HGNC:4761]",{"v":1.167301,"d":"1.17"},{"v":2.46816,"d":"2.47"},{"v":0.472943812394658,"d":"0.47"},{"v":-1.08025929904915,"d":"-1.08"},{"v":0.0544704217045806,"d":"0.05"},{"v":0.53611509261579,"d":"0.54"},"down","no"]
["ENSG00000112394","SLC16A10","ENST00000439288;ENST00000368850;ENST00000368851;ENST00000419619;ENST00000612036","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0055085(transmembrane transport);GO:0005887(integral component of plasma membrane);GO:0005886(plasma membrane);GO:0003333(amino acid transmembrane transport);GO:0015173(aromatic amino acid transmembrane transporter activity);GO:0015349(thyroid hormone transmembrane transporter activity);GO:0070327(thyroid hormone transport);GO:0016323(basolateral plasma membrane);GO:0015171(amino acid transmembrane transporter activity);GO:0008028(monocarboxylic acid transmembrane transporter activity);GO:0006865(amino acid transport);GO:0015718(monocarboxylic acid transport);GO:0015801(aromatic amino acid transport);GO:0015801(aromatic amino acid transport)","04919(Thyroid hormone signaling pathway);04974(Protein digestion and absorption);04974(Protein digestion and absorption)","K08187","NA","solute carrier family 16 member 10 [Source:HGNC Symbol;Acc:HGNC:17027]",{"v":0.251825984782415,"d":"0.25"},{"v":0.0799464878526297,"d":"0.08"},{"v":3.14993180496711,"d":"3.15"},{"v":1.65532059505676,"d":"1.66"},{"v":0.0544704217045806,"d":"0.05"},{"v":0.53611509261579,"d":"0.54"},"up","no"]
["MSTRG.13503","TMEM106B","ENST00000396668;ENST00000462754;ENST00000444443;ENST00000420833;ENST00000396667;ENST00000492762","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005765(lysosomal membrane);GO:0005764(lysosome);GO:0005768(endosome);GO:0005515(protein binding);GO:0031902(late endosome membrane);GO:0003674(molecular_function);GO:0070062(extracellular exosome);GO:0048813(dendrite morphogenesis);GO:0032418(lysosome localization);GO:0007040(lysosome organization);GO:0007041(lysosomal transport);GO:1900006(positive regulation of dendrite development);GO:1900006(positive regulation of dendrite development)","NA","NA","NA","transmembrane protein 106B [Source:HGNC Symbol;Acc:HGNC:22407]",{"v":0.487619339078388,"d":"0.49"},{"v":0.991439655873657,"d":"0.99"},{"v":0.491829569444343,"d":"0.49"},{"v":-1.02376962061154,"d":"-1.02"},{"v":0.054519974688663,"d":"0.05"},{"v":0.53611509261579,"d":"0.54"},"down","no"]
["MSTRG.1808","AC022400.8","ENST00000623453","NA","NA","NA","NA",null,{"v":0.282639,"d":"0.28"},{"v":0.595221,"d":"0.60"},{"v":0.474847157610366,"d":"0.47"},{"v":-1.07446487711008,"d":"-1.07"},{"v":0.0545209613690905,"d":"0.05"},{"v":0.53611509261579,"d":"0.54"},"down","no"]
["MSTRG.1122","CD48","ENST00000368046;ENST00000613788;ENST00000368045","GO:0016020(membrane);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0031225(anchored component of membrane);GO:0045121(membrane raft);GO:0004872(receptor activity);GO:0050900(leukocyte migration);GO:0002819(regulation of adaptive immune response);GO:0070062(extracellular exosome);GO:0005887(integral component of plasma membrane);GO:0006952(defense response);GO:0003823(antigen binding);GO:0007165(signal transduction);GO:0042110(T cell activation);GO:0045576(mast cell activation);GO:0009897(external side of plasma membrane);GO:0043234(protein complex);GO:0046658(anchored component of plasma membrane);GO:0046658(anchored component of plasma membrane)","04650(Natural killer cell mediated cytotoxicity);04650(Natural killer cell mediated cytotoxicity)","K06479","NA","CD48 molecule [Source:HGNC Symbol;Acc:HGNC:1683]",{"v":59.311446541234,"d":"59.31"},{"v":119.117519707392,"d":"119.12"},{"v":0.497923787255901,"d":"0.50"},{"v":-1.00600315613256,"d":"-1.01"},{"v":0.0546721669687604,"d":"0.05"},{"v":0.536212902896921,"d":"0.54"},"down","no"]
["MSTRG.6983","GNGT2","ENST00000507680;ENST00000515635;ENST00000511673;ENST00000511277;ENST00000503070;ENST00000300406","GO:0016020(membrane);GO:0007186(G-protein coupled receptor signaling pathway);GO:0004871(signal transducer activity);GO:0005886(plasma membrane);GO:0007165(signal transduction);GO:0005834(heterotrimeric G-protein complex);GO:0003924(GTPase activity);GO:0007602(phototransduction);GO:0007602(phototransduction)","04014(Ras signaling pathway);04371(Apelin signaling pathway);04151(PI3K-Akt signaling pathway);04062(Chemokine signaling pathway);04926(Relaxin signaling pathway);04724(Glutamatergic synapse);04727(GABAergic synapse);04725(Cholinergic synapse);04728(Dopaminergic synapse);04726(Serotonergic synapse);04723(Retrograde endocannabinoid signaling);04713(Circadian entrainment);05200(Pathways in cancer);05032(Morphine addiction);05034(Alcoholism);05167(Kaposi's sarcoma-associated herpesvirus infection);05167(Kaposi's sarcoma-associated herpesvirus infection)","K04549","NA","G protein subunit gamma transducin 2 [Source:HGNC Symbol;Acc:HGNC:4412]",{"v":0.630111883955003,"d":"0.63"},{"v":1.35134973238603,"d":"1.35"},{"v":0.46628335275017,"d":"0.47"},{"v":-1.10072117139333,"d":"-1.10"},{"v":0.0546741875263093,"d":"0.05"},{"v":0.536212902896921,"d":"0.54"},"down","no"]
["MSTRG.6289","PRPF8","ENST00000304992;MSTRG.6289.1;ENST00000576585;ENST00000573681;ENST00000576407;ENST00000577001;ENST00000573725;ENST00000573716;ENST00000572723;ENST00000572621;ENST00000576958;ENST00000572445;ENST00000575116;ENST00000571346;ENST00000574728;ENST00000574217","GO:0005681(spliceosomal complex);GO:0000398(mRNA splicing, via spliceosome);GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0006397(mRNA processing);GO:0008380(RNA splicing);GO:0005634(nucleus);GO:0016607(nuclear speck);GO:0016020(membrane);GO:0030529(intracellular ribonucleoprotein complex);GO:0005515(protein binding);GO:0005654(nucleoplasm);GO:0017070(U6 snRNA binding);GO:0030623(U5 snRNA binding);GO:0000386(second spliceosomal transesterification activity);GO:0000375(RNA splicing, via transesterification reactions);GO:0046540(U4/U6 x U5 tri-snRNP complex);GO:0071013(catalytic step 2 spliceosome);GO:0000244(spliceosomal tri-snRNP complex assembly);GO:0030619(U1 snRNA binding);GO:0030620(U2 snRNA binding);GO:0070530(K63-linked polyubiquitin binding);GO:0097157(pre-mRNA intronic binding);GO:0005682(U5 snRNP);GO:0071222(cellular response to lipopolysaccharide);GO:0071356(cellular response to tumor necrosis factor);GO:0030532(small nuclear ribonucleoprotein complex);GO:0030532(small nuclear ribonucleoprotein complex)","03040(Spliceosome);03040(Spliceosome)","K12856","NA","pre-mRNA processing factor 8 [Source:HGNC Symbol;Acc:HGNC:17340]",{"v":22.9775322549468,"d":"22.98"},{"v":7.87401575868437,"d":"7.87"},{"v":2.91814659243024,"d":"2.92"},{"v":1.5450523585334,"d":"1.55"},{"v":0.0547050350032338,"d":"0.05"},{"v":0.536212902896921,"d":"0.54"},"up","no"]
["ENSG00000083844","ZNF264","ENST00000263095;ENST00000594126;ENST00000600531;ENST00000599653","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0005622(intracellular);GO:0005622(intracellular)","NA","NA","NA","zinc finger protein 264 [Source:HGNC Symbol;Acc:HGNC:13057]",{"v":2.39642027848707,"d":"2.40"},{"v":0.817940814794127,"d":"0.82"},{"v":2.92982112537108,"d":"2.93"},{"v":1.55081258634799,"d":"1.55"},{"v":0.0547156023364206,"d":"0.05"},{"v":0.536212902896921,"d":"0.54"},"up","no"]
["ENSG00000151135","TMEM263","ENST00000548125;ENST00000280756;ENST00000547081;ENST00000551813;ENST00000548806;ENST00000550344;ENST00000551237;ENST00000547242;ENST00000551489","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016021(integral component of membrane)","NA","NA","NA","transmembrane protein 263 [Source:HGNC Symbol;Acc:HGNC:28281]",{"v":0.452876174916107,"d":"0.45"},{"v":0.931948353187919,"d":"0.93"},{"v":0.48594557130441,"d":"0.49"},{"v":-1.04113336213988,"d":"-1.04"},{"v":0.0549473615788228,"d":"0.05"},{"v":0.538030109624679,"d":"0.54"},"down","no"]
["MSTRG.7349","FASN","ENST00000306749;ENST00000584610;ENST00000635197;ENST00000637026;ENST00000578424;ENST00000636628","GO:0003723(RNA binding);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005794(Golgi apparatus);GO:0005829(cytosol);GO:0016740(transferase activity);GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0016787(hydrolase activity);GO:0003824(catalytic activity);GO:0016829(lyase activity);GO:0006629(lipid metabolic process);GO:0008152(metabolic process);GO:0009058(biosynthetic process);GO:0005886(plasma membrane);GO:0006631(fatty acid metabolic process);GO:0006633(fatty acid biosynthetic process);GO:0005515(protein binding);GO:0042470(melanosome);GO:0016788(hydrolase activity, acting on ester bonds);GO:0004315(3-oxoacyl-[acyl-carrier-protein] synthase activity);GO:0004312(fatty acid synthase activity);GO:0004313([acyl-carrier-protein] S-acetyltransferase activity);GO:0004314([acyl-carrier-protein] S-malonyltransferase activity);GO:0004316(3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity);GO:0004317(3-hydroxypalmitoyl-[acyl-carrier-protein] dehydratase activity);GO:0004319(enoyl-[acyl-carrier-protein] reductase (NADPH, B-specific) activity);GO:0004320(oleoyl-[acyl-carrier-protein] hydrolase activity);GO:0016295(myristoyl-[acyl-carrier-protein] hydrolase activity);GO:0016296(palmitoyl-[acyl-carrier-protein] hydrolase activity);GO:0016297(acyl-[acyl-carrier-protein] hydrolase activity);GO:0031177(phosphopantetheine binding);GO:0045296(cadherin binding);GO:0070062(extracellular exosome);GO:0031325(positive regulation of cellular metabolic process);GO:0045540(regulation of cholesterol biosynthetic process);GO:0046949(fatty-acyl-CoA biosynthetic process);GO:0001649(osteoblast differentiation);GO:0015939(pantothenate metabolic process);GO:0008144(drug binding);GO:0019171(3-hydroxyacyl-[acyl-carrier-protein] dehydratase activity);GO:0042802(identical protein binding);GO:0042803(protein homodimerization activity);GO:0047117(enoyl-[acyl-carrier-protein] reductase (NADPH, A-specific) activity);GO:0047451(3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity);GO:0070402(NADPH binding);GO:0102131(3-oxo-glutaryl-[acp] methyl ester reductase activity);GO:0102132(3-oxo-pimeloyl-[acp] methyl ester reductase activity);GO:0006084(acetyl-CoA metabolic process);GO:0030879(mammary gland development);GO:0071353(cellular response to interleukin-4);GO:0005739(mitochondrion);GO:0042587(glycogen granule);GO:0042587(glycogen granule)","00061(Fatty acid biosynthesis);04152(AMPK signaling pathway);04910(Insulin signaling pathway);04910(Insulin signaling pathway)","K00665","EC:2.3.1.85","fatty acid synthase [Source:HGNC Symbol;Acc:HGNC:3594]",{"v":2.82538293966254,"d":"2.83"},{"v":0.965504101452371,"d":"0.97"},{"v":2.926329298252,"d":"2.93"},{"v":1.54909212430348,"d":"1.55"},{"v":0.0551126824561872,"d":"0.06"},{"v":0.539194255571779,"d":"0.54"},"up","no"]
["ENSG00000174197","MGA","ENST00000219905;ENST00000566288;ENST00000568255;ENST00000564190;ENST00000563576;ENST00000566586","GO:0005634(nucleus);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0046983(protein dimerization activity);GO:0005515(protein binding);GO:0071339(MLL1 complex);GO:0071339(MLL1 complex)","NA","NA","NA","MGA, MAX dimerization protein [Source:HGNC Symbol;Acc:HGNC:14010]",{"v":2.75034786221744,"d":"2.75"},{"v":0.942218736728797,"d":"0.94"},{"v":2.91901206694968,"d":"2.92"},{"v":1.54548017483212,"d":"1.55"},{"v":0.0552463876197607,"d":"0.06"},{"v":0.540047390091146,"d":"0.54"},"up","no"]
["MSTRG.955","POGZ","ENST00000271715;ENST00000485040;ENST00000497787;ENST00000495253;ENST00000450842;ENST00000441516;ENST00000409503;ENST00000491586;ENST00000533351;ENST00000467287;ENST00000482678;ENST00000492528;ENST00000533461;ENST00000531094;ENST00000439756;ENST00000358476;ENST00000476128","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0003677(DNA binding);GO:0051301(cell division);GO:0000790(nuclear chromatin);GO:0005694(chromosome);GO:0005515(protein binding);GO:0007049(cell cycle);GO:0051382(kinetochore assembly);GO:0007064(mitotic sister chromatid cohesion);GO:0007064(mitotic sister chromatid cohesion)","NA","NA","NA","pogo transposable element derived with ZNF domain [Source:HGNC Symbol;Acc:HGNC:18801]",{"v":4.53792808820093,"d":"4.54"},{"v":1.5533030334891,"d":"1.55"},{"v":2.92146991949641,"d":"2.92"},{"v":1.54669443485311,"d":"1.55"},{"v":0.0553069273981252,"d":"0.06"},{"v":0.540060170751927,"d":"0.54"},"up","no"]
["ENSG00000213064","SFT2D2","ENST00000271375;ENST00000471981;ENST00000630869","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0015031(protein transport);GO:0016192(vesicle-mediated transport);GO:0003674(molecular_function);GO:0008150(biological_process);GO:0070062(extracellular exosome);GO:0070062(extracellular exosome)","NA","NA","NA","SFT2 domain containing 2 [Source:HGNC Symbol;Acc:HGNC:25140]",{"v":4.68466833196685,"d":"4.68"},{"v":1.60630671776134,"d":"1.61"},{"v":2.91642205076234,"d":"2.92"},{"v":1.54419951475464,"d":"1.54"},{"v":0.0553752949866419,"d":"0.06"},{"v":0.540060170751927,"d":"0.54"},"up","no"]
["MSTRG.6042","CENPT","ENST00000565157;ENST00000565436;ENST00000564128;ENST00000562338;ENST00000569862;ENST00000567985;ENST00000566067;ENST00000565385;ENST00000574569;ENST00000436104;ENST00000568765;ENST00000562462;ENST00000562483;ENST00000562787;ENST00000563885;ENST00000562513;ENST00000568495;ENST00000626059","GO:0005634(nucleus);GO:0003677(DNA binding);GO:0051301(cell division);GO:0046982(protein heterodimerization activity);GO:0005694(chromosome);GO:0007049(cell cycle);GO:0016604(nuclear body);GO:0000776(kinetochore);GO:0051382(kinetochore assembly);GO:0007059(chromosome segregation);GO:0000775(chromosome, centromeric region);GO:0000777(condensed chromosome kinetochore);GO:0005515(protein binding);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0034080(CENP-A containing nucleosome assembly);GO:0007062(sister chromatid cohesion);GO:0000278(mitotic cell cycle);GO:0042393(histone binding);GO:0051276(chromosome organization);GO:0000788(nuclear nucleosome);GO:1903394(protein localization to kinetochore involved in kinetochore assembly);GO:1903394(protein localization to kinetochore involved in kinetochore assembly)","NA","NA","NA","centromere protein T [Source:HGNC Symbol;Acc:HGNC:25787]",{"v":2.38998386477704,"d":"2.39"},{"v":4.80922505235602,"d":"4.81"},{"v":0.496958208184954,"d":"0.50"},{"v":-1.00880356177066,"d":"-1.01"},{"v":0.0554295103324478,"d":"0.06"},{"v":0.540060170751927,"d":"0.54"},"down","no"]
["MSTRG.653","AC113935.1","ENST00000471722","NA","NA","NA","NA",null,{"v":34.568447,"d":"34.57"},{"v":69.404442,"d":"69.40"},{"v":0.498072544117565,"d":"0.50"},{"v":-1.00557220918736,"d":"-1.01"},{"v":0.0554399730951075,"d":"0.06"},{"v":0.540060170751927,"d":"0.54"},"down","no"]
["ENSG00000125375","ATP5S","ENST00000556962;ENST00000358473;ENST00000557421;ENST00000554438;ENST00000554951;ENST00000555939;ENST00000311459;ENST00000554204;ENST00000553774;ENST00000426751","GO:0006810(transport);GO:0016020(membrane);GO:0046872(metal ion binding);GO:0005743(mitochondrial inner membrane);GO:0005739(mitochondrion);GO:0006811(ion transport);GO:0015992(proton transport);GO:0006754(ATP biosynthetic process);GO:0042407(cristae formation);GO:0042776(mitochondrial ATP synthesis coupled proton transport);GO:0045263(proton-transporting ATP synthase complex, coupling factor F(o));GO:0015078(hydrogen ion transmembrane transporter activity);GO:0015078(hydrogen ion transmembrane transporter activity)","NA","NA","NA","ATP synthase, H+ transporting, mitochondrial Fo complex subunit s (factor B) [Source:HGNC Symbol;Acc:HGNC:18799]",{"v":0.269778562715765,"d":"0.27"},{"v":0.555847590245198,"d":"0.56"},{"v":0.485346284575524,"d":"0.49"},{"v":-1.04291364701782,"d":"-1.04"},{"v":0.0555159066526519,"d":"0.06"},{"v":0.540060170751927,"d":"0.54"},"down","no"]
["MSTRG.9368","FAM117B","ENST00000392238","GO:0005515(protein binding)","NA","NA","NA","family with sequence similarity 117 member B [Source:HGNC Symbol;Acc:HGNC:14440]",{"v":4.97133844219846,"d":"4.97"},{"v":1.70313401787504,"d":"1.70"},{"v":2.91893555646377,"d":"2.92"},{"v":1.54544235972801,"d":"1.55"},{"v":0.0555385124885867,"d":"0.06"},{"v":0.540060170751927,"d":"0.54"},"up","no"]
["MSTRG.10242","DDT;AC253536.5","ENST00000398344;ENST00000506097;ENST00000403754;ENST00000428792;ENST00000444947","GO:0005737(cytoplasm);GO:0016829(lyase activity);GO:0070062(extracellular exosome);GO:0042438(melanin biosynthetic process);GO:0004167(dopachrome isomerase activity);GO:0033981(D-dopachrome decarboxylase activity);GO:0033981(D-dopachrome decarboxylase activity)","NA","NA","NA","D-dopachrome tautomerase [Source:HGNC Symbol;Acc:HGNC:2732]",{"v":4.27697806353306,"d":"4.28"},{"v":8.62835699948347,"d":"8.63"},{"v":0.495688584024641,"d":"0.50"},{"v":-1.0124940617412,"d":"-1.01"},{"v":0.0555777764139021,"d":"0.06"},{"v":0.540060170751927,"d":"0.54"},"down","no"]
["MSTRG.12884","HSPA1A;HSPA1B","ENST00000608703;ENST00000375651;ENST00000375650;MSTRG.12884.1","GO:0010628(positive regulation of gene expression);GO:0048471(perinuclear region of cytoplasm);GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016607(nuclear speck);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0030529(intracellular ribonucleoprotein complex);GO:0005829(cytosol);GO:0005783(endoplasmic reticulum);GO:0005739(mitochondrion);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0005925(focal adhesion);GO:0005813(centrosome);GO:0005815(microtubule organizing center);GO:0005576(extracellular region);GO:0046718(viral entry into host cell);GO:0006986(response to unfolded protein);GO:0005654(nucleoplasm);GO:0045296(cadherin binding);GO:0070062(extracellular exosome);GO:0050821(protein stabilization);GO:0005814(centriole);GO:0008285(negative regulation of cell proliferation);GO:0072562(blood microparticle);GO:0043488(regulation of mRNA stability);GO:0043234(protein complex);GO:0005102(receptor binding);GO:0043312(neutrophil degranulation);GO:0047485(protein N-terminus binding);GO:0043066(negative regulation of apoptotic process);GO:0051092(positive regulation of NF-kappaB transcription factor activity);GO:0030308(negative regulation of cell growth);GO:1904813(ficolin-1-rich granule lumen);GO:0031982(vesicle);GO:0051082(unfolded protein binding);GO:0019899(enzyme binding);GO:2001240(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand);GO:0031625(ubiquitin protein ligase binding);GO:0001618(virus receptor activity);GO:0030512(negative regulation of transforming growth factor beta receptor signaling pathway);GO:0016235(aggresome);GO:0000151(ubiquitin ligase complex);GO:0042826(histone deacetylase binding);GO:1900034(regulation of cellular response to heat);GO:0034599(cellular response to oxidative stress);GO:0034605(cellular response to heat);GO:0060548(negative regulation of cell death);GO:1901673(regulation of mitotic spindle assembly);GO:1902236(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway);GO:0042623(ATPase activity, coupled);GO:0001664(G-protein coupled receptor binding);GO:0042026(protein refolding);GO:0032436(positive regulation of proteasomal ubiquitin-dependent protein catabolic process);GO:0031072(heat shock protein binding);GO:0090084(negative regulation of inclusion body assembly);GO:0097718(disordered domain specific binding);GO:0006402(mRNA catabolic process);GO:0001106(RNA polymerase II transcription corepressor activity);GO:0016887(ATPase activity);GO:0097201(negative regulation of transcription from RNA polymerase II promoter in response to stress);GO:0032757(positive regulation of interleukin-8 production);GO:0046034(ATP metabolic process);GO:0031396(regulation of protein ubiquitination);GO:0051131(chaperone-mediated protein complex assembly);GO:0031249(denatured protein binding);GO:0044183(protein binding involved in protein folding);GO:0055131(C3HC4-type RING finger domain binding);GO:0031397(negative regulation of protein ubiquitination);GO:0070370(cellular heat acclimation);GO:0070434(positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway);GO:0090063(positive regulation of microtubule nucleation);GO:1901029(negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway);GO:1902380(positive regulation of endoribonuclease activity);GO:1903265(positive regulation of tumor necrosis factor-mediated signaling pathway);GO:1904722(positive regulation of mRNA endonucleolytic cleavage involved in unfolded protein response);GO:0016234(inclusion body);GO:0016234(inclusion body)","03040(Spliceosome);04141(Protein processing in endoplasmic reticulum);04010(MAPK signaling pathway);04144(Endocytosis);04612(Antigen processing and presentation);04915(Estrogen signaling pathway);04213(Longevity regulating pathway - multiple species);05020(Prion diseases);05134(Legionellosis);05162(Measles);05164(Influenza A);05169(Epstein-Barr virus infection);05145(Toxoplasmosis);05145(Toxoplasmosis)","K03283","NA","heat shock protein family A (Hsp70) member 1A [Source:HGNC Symbol;Acc:HGNC:5232];heat shock protein family A (Hsp70) member 1B [Source:HGNC Symbol;Acc:HGNC:5233]",{"v":11.9947939298561,"d":"11.99"},{"v":4.1195774676259,"d":"4.12"},{"v":2.9116563589636,"d":"2.91"},{"v":1.54184009507168,"d":"1.54"},{"v":0.0556890816613437,"d":"0.06"},{"v":0.540060170751927,"d":"0.54"},"up","no"]
["ENSG00000087258","GNAO1","ENST00000640560;ENST00000638705;ENST00000262494;ENST00000639251;ENST00000563661;ENST00000564798;ENST00000640390;ENST00000262493;ENST00000568375;ENST00000638185","GO:0016020(membrane);GO:0005525(GTP binding);GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0007186(G-protein coupled receptor signaling pathway);GO:0007165(signal transduction);GO:0003924(GTPase activity);GO:0004871(signal transducer activity);GO:0005886(plasma membrane);GO:0019001(guanyl nucleotide binding);GO:0031683(G-protein beta/gamma-subunit complex binding);GO:0007188(adenylate cyclase-modulating G-protein coupled receptor signaling pathway);GO:0006457(protein folding);GO:0005834(heterotrimeric G-protein complex);GO:0006936(muscle contraction);GO:0007223(Wnt signaling pathway, calcium modulating pathway);GO:0031821(G-protein coupled serotonin receptor binding);GO:0031852(mu-type opioid receptor binding);GO:0051430(corticotropin-releasing hormone receptor 1 binding);GO:0007212(dopamine receptor signaling pathway);GO:0032403(protein complex binding);GO:0032794(GTPase activating protein binding);GO:0007568(aging);GO:0007626(locomotory behavior);GO:0008016(regulation of heart contraction);GO:0009987(cellular process);GO:0010243(response to organonitrogen compound);GO:0014070(response to organic cyclic compound);GO:0030900(forebrain development);GO:0031175(neuron projection development);GO:0034097(response to cytokine);GO:0042493(response to drug);GO:0042542(response to hydrogen peroxide);GO:0043278(response to morphine);GO:0043547(positive regulation of GTPase activity);GO:0051926(negative regulation of calcium ion transport);GO:0030425(dendrite);GO:0043005(neuron projection);GO:0043209(myelin sheath);GO:0043234(protein complex);GO:0044297(cell body);GO:0044297(cell body)","04015(Rap1 signaling pathway);04915(Estrogen signaling pathway);04921(Oxytocin signaling pathway);04926(Relaxin signaling pathway);04916(Melanogenesis);04724(Glutamatergic synapse);04727(GABAergic synapse);04725(Cholinergic synapse);04728(Dopaminergic synapse);04726(Serotonergic synapse);04730(Long-term depression);04723(Retrograde endocannabinoid signaling);04713(Circadian entrainment);05032(Morphine addiction);05034(Alcoholism);05145(Toxoplasmosis);05142(Chagas disease (American trypanosomiasis));05142(Chagas disease (American trypanosomiasis))","K04534","NA","G protein subunit alpha o1 [Source:HGNC Symbol;Acc:HGNC:4389]",{"v":0.274100788858874,"d":"0.27"},{"v":0.0908707035847266,"d":"0.09"},{"v":3.01638237678336,"d":"3.02"},{"v":1.59281932586189,"d":"1.59"},{"v":0.055703692966162,"d":"0.06"},{"v":0.540060170751927,"d":"0.54"},"up","no"]
["MSTRG.9079","CLASP1","ENST00000541377;ENST00000452274;ENST00000409078;ENST00000397587;ENST00000430234;ENST00000449975;ENST00000491646;ENST00000474065;ENST00000485112;ENST00000263710;ENST00000463621;ENST00000472776;ENST00000480007","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005794(Golgi apparatus);GO:0051301(cell division);GO:0005694(chromosome);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0007049(cell cycle);GO:0005874(microtubule);GO:0005925(focal adhesion);GO:0008017(microtubule binding);GO:0005813(centrosome);GO:0005815(microtubule organizing center);GO:0005819(spindle);GO:0000775(chromosome, centromeric region);GO:0000776(kinetochore);GO:0000777(condensed chromosome kinetochore);GO:0043515(kinetochore binding);GO:0070507(regulation of microtubule cytoskeleton organization);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0000086(G2/M transition of mitotic cell cycle);GO:0010389(regulation of G2/M transition of mitotic cell cycle);GO:0097711(ciliary basal body docking);GO:0051010(microtubule plus-end binding);GO:0005828(kinetochore microtubule);GO:0005881(cytoplasmic microtubule);GO:0010717(regulation of epithelial to mesenchymal transition);GO:0005876(spindle microtubule);GO:0007052(mitotic spindle organization);GO:0007062(sister chromatid cohesion);GO:0090307(mitotic spindle assembly);GO:0045921(positive regulation of exocytosis);GO:0000226(microtubule cytoskeleton organization);GO:0002162(dystroglycan binding);GO:0010458(exit from mitosis);GO:0007030(Golgi organization);GO:0010634(positive regulation of epithelial cell migration);GO:0051893(regulation of focal adhesion assembly);GO:0001578(microtubule bundle formation);GO:0090162(establishment of epithelial cell polarity);GO:0005938(cell cortex);GO:0006903(vesicle targeting);GO:0007020(microtubule nucleation);GO:0007026(negative regulation of microtubule depolymerization);GO:0007163(establishment or maintenance of cell polarity);GO:0010470(regulation of gastrulation);GO:0031023(microtubule organizing center organization);GO:0034453(microtubule anchoring);GO:0051497(negative regulation of stress fiber assembly);GO:0090091(positive regulation of extracellular matrix disassembly);GO:1903690(negative regulation of wound healing, spreading of epidermal cells);GO:1904261(positive regulation of basement membrane assembly involved in embryonic body morphogenesis);GO:0045180(basal cortex);GO:0031116(positive regulation of microtubule polymerization);GO:0030953(astral microtubule organization);GO:0051294(establishment of spindle orientation);GO:0035371(microtubule plus-end);GO:0031111(negative regulation of microtubule polymerization or depolymerization);GO:0040001(establishment of mitotic spindle localization);GO:0030981(cortical microtubule cytoskeleton);GO:0031592(centrosomal corona);GO:0031592(centrosomal corona)","NA","NA","NA","cytoplasmic linker associated protein 1 [Source:HGNC Symbol;Acc:HGNC:17088]",{"v":4.30862985640608,"d":"4.31"},{"v":1.47863538418386,"d":"1.48"},{"v":2.91392313648997,"d":"2.91"},{"v":1.542962822472,"d":"1.54"},{"v":0.0557409714986534,"d":"0.06"},{"v":0.540060170751927,"d":"0.54"},"up","no"]
["MSTRG.3356","SMARCD1","ENST00000394963;ENST00000381513;ENST00000547247;ENST00000551352;ENST00000549274;ENST00000551966;ENST00000549526;ENST00000548573;ENST00000550280","GO:0005634(nucleus);GO:0043231(intracellular membrane-bounded organelle);GO:0005654(nucleoplasm);GO:0016569(covalent chromatin modification);GO:0005515(protein binding);GO:0007399(nervous system development);GO:0003713(transcription coactivator activity);GO:0006338(chromatin remodeling);GO:0006337(nucleosome disassembly);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0048096(chromatin-mediated maintenance of transcription);GO:0016514(SWI/SNF complex);GO:0071564(npBAF complex);GO:0071565(nBAF complex);GO:0032947(protein complex scaffold);GO:0003682(chromatin binding);GO:0005102(receptor binding);GO:0071398(cellular response to fatty acid);GO:0090544(BAF-type complex);GO:0090544(BAF-type complex)","05225(Hepatocellular carcinoma);05225(Hepatocellular carcinoma)","K11650","NA","SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1 [Source:HGNC Symbol;Acc:HGNC:11106]",{"v":5.56753792815421,"d":"5.57"},{"v":1.89824218905763,"d":"1.90"},{"v":2.93299662195274,"d":"2.93"},{"v":1.55237540948736,"d":"1.55"},{"v":0.0559135692846806,"d":"0.06"},{"v":0.540060170751927,"d":"0.54"},"up","no"]
["ENSG00000225151","GOLGA2P7","ENST00000557881;ENST00000561015;ENST00000560408;ENST00000559668;ENST00000559654;ENST00000316967;ENST00000559990;ENST00000557980;ENST00000400817","NA","NA","NA","NA","golgin A2 pseudogene 7 [Source:HGNC Symbol;Acc:HGNC:49516]",{"v":0.520366380467955,"d":"0.52"},{"v":0.163988231536114,"d":"0.16"},{"v":3.17319343951434,"d":"3.17"},{"v":1.66593547137267,"d":"1.67"},{"v":0.0559544112126931,"d":"0.06"},{"v":0.540060170751927,"d":"0.54"},"up","no"]
["MSTRG.1957","USMG5;MIR1307","ENST00000337003;ENST00000309579;ENST00000408840;ENST00000369815;ENST00000369811","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005739(mitochondrion);GO:0031966(mitochondrial membrane);GO:0070062(extracellular exosome);GO:0005753(mitochondrial proton-transporting ATP synthase complex);GO:0005743(mitochondrial inner membrane);GO:0005615(extracellular space);GO:0005743(mitochondrial inner membrane)","NA","NA","NA","up-regulated during skeletal muscle growth 5 homolog (mouse) [Source:HGNC Symbol;Acc:HGNC:30889];microRNA 1307 [Source:HGNC Symbol;Acc:HGNC:35372]",{"v":10.5782162342541,"d":"10.58"},{"v":21.2691090651934,"d":"21.27"},{"v":0.497351167922929,"d":"0.50"},{"v":-1.0076632303841,"d":"-1.01"},{"v":0.055983142202972,"d":"0.06"},{"v":0.540060170751927,"d":"0.54"},"down","no"]
["ENSG00000234420","ZNF37BP","ENST00000452075;ENST00000435805;ENST00000473592","NA","NA","NA","NA","zinc finger protein 37B, pseudogene [Source:HGNC Symbol;Acc:HGNC:13103]",{"v":0.755150155421217,"d":"0.76"},{"v":0.254204559282371,"d":"0.25"},{"v":2.97063969880412,"d":"2.97"},{"v":1.57077363503865,"d":"1.57"},{"v":0.0560350223478995,"d":"0.06"},{"v":0.540060170751927,"d":"0.54"},"up","no"]
["MSTRG.3705","C12orf76;AC007546.2","ENST00000546651;ENST00000551185;ENST00000623996;ENST00000548191;ENST00000546627;ENST00000549724;ENST00000548936;ENST00000547573;ENST00000309050","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005524(ATP binding);GO:0005216(ion channel activity);GO:0006811(ion transport);GO:0005887(integral component of plasma membrane);GO:0098655(cation transmembrane transport);GO:0060079(excitatory postsynaptic potential);GO:0001614(purinergic nucleotide receptor activity);GO:0004931(extracellular ATP-gated cation channel activity);GO:0033198(response to ATP);GO:0035590(purinergic nucleotide receptor signaling pathway);GO:0098794(postsynapse);GO:0098794(postsynapse)","NA","NA","NA","chromosome 12 open reading frame 76 [Source:HGNC Symbol;Acc:HGNC:33790]",{"v":0.585497520819113,"d":"0.59"},{"v":1.19055720955631,"d":"1.19"},{"v":0.491784448592196,"d":"0.49"},{"v":-1.02390198072127,"d":"-1.02"},{"v":0.0560460099200103,"d":"0.06"},{"v":0.540060170751927,"d":"0.54"},"down","no"]
["MSTRG.1745","DDX21","ENST00000354185;ENST00000620315","GO:0005634(nucleus);GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0016020(membrane);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0005730(nucleolus);GO:0016787(hydrolase activity);GO:0006351(transcription, DNA-templated);GO:0004386(helicase activity);GO:0005515(protein binding);GO:0005654(nucleoplasm);GO:0006364(rRNA processing);GO:0005737(cytoplasm);GO:0006366(transcription from RNA polymerase II promoter);GO:0010501(RNA secondary structure unwinding);GO:0019843(rRNA binding);GO:0045815(positive regulation of gene expression, epigenetic);GO:0004004(ATP-dependent RNA helicase activity);GO:0001649(osteoblast differentiation);GO:0097322(7SK snRNA binding);GO:0030515(snoRNA binding);GO:0003725(double-stranded RNA binding);GO:0009615(response to virus);GO:0043330(response to exogenous dsRNA);GO:0043330(response to exogenous dsRNA)","NA","NA","NA","DExD-box helicase 21 [Source:HGNC Symbol;Acc:HGNC:2744]",{"v":13.9123424432271,"d":"13.91"},{"v":4.78609294800797,"d":"4.79"},{"v":2.90682663173468,"d":"2.91"},{"v":1.53944502916414,"d":"1.54"},{"v":0.0561273939923746,"d":"0.06"},{"v":0.540060170751927,"d":"0.54"},"up","no"]
["MSTRG.9648","MAPRE1","ENST00000375571","GO:0003723(RNA binding);GO:0005737(cytoplasm);GO:0051301(cell division);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0007049(cell cycle);GO:0008017(microtubule binding);GO:0005874(microtubule);GO:0070507(regulation of microtubule cytoskeleton organization);GO:0005813(centrosome);GO:0005815(microtubule organizing center);GO:0005819(spindle);GO:0042802(identical protein binding);GO:0005829(cytosol);GO:0045296(cadherin binding);GO:0000086(G2/M transition of mitotic cell cycle);GO:0010389(regulation of G2/M transition of mitotic cell cycle);GO:0097711(ciliary basal body docking);GO:0051010(microtubule plus-end binding);GO:0007062(sister chromatid cohesion);GO:0008283(cell proliferation);GO:0035372(protein localization to microtubule);GO:0008022(protein C-terminus binding);GO:0031115(negative regulation of microtubule polymerization);GO:0030335(positive regulation of cell migration);GO:1903033(positive regulation of microtubule plus-end binding);GO:1904527(negative regulation of microtubule binding);GO:0005794(Golgi apparatus);GO:0005881(cytoplasmic microtubule);GO:0015630(microtubule cytoskeleton);GO:0030981(cortical microtubule cytoskeleton);GO:0031253(cell projection membrane);GO:0035371(microtubule plus-end);GO:0042995(cell projection)","NA","NA","NA","microtubule associated protein RP/EB family member 1 [Source:HGNC Symbol;Acc:HGNC:6890]",{"v":16.767239,"d":"16.77"},{"v":33.50576,"d":"33.51"},{"v":0.50042855318011,"d":"0.50"},{"v":-0.998763986526466,"d":"-1.00"},{"v":0.0562351075935952,"d":"0.06"},{"v":0.540060170751927,"d":"0.54"},"down","no"]
["MSTRG.13968","LINC-PINT","ENST00000451786;ENST00000431189;ENST00000433079;ENST00000435523;ENST00000429901;ENST00000416999;ENST00000423414","NA","NA","NA","NA","long intergenic non-protein coding RNA, p53 induced transcript [Source:HGNC Symbol;Acc:HGNC:26885]",{"v":1.26456736522702,"d":"1.26"},{"v":2.55272142945736,"d":"2.55"},{"v":0.495380087554572,"d":"0.50"},{"v":-1.01339221613682,"d":"-1.01"},{"v":0.0562554717177414,"d":"0.06"},{"v":0.540060170751927,"d":"0.54"},"down","no"]
["ENSG00000204104","TRAF3IP1","ENST00000462122;ENST00000409739;ENST00000483951;ENST00000391993;ENST00000373327","GO:0005737(cytoplasm);GO:0005856(cytoskeleton);GO:0042995(cell projection);GO:0005515(protein binding);GO:0008017(microtubule binding);GO:0005813(centrosome);GO:0070507(regulation of microtubule cytoskeleton organization);GO:0035735(intraciliary transport involved in cilium assembly);GO:0005929(cilium);GO:0030992(intraciliary transport particle B);GO:0097542(ciliary tip);GO:0030030(cell projection organization);GO:0097546(ciliary base);GO:0060271(cilium assembly);GO:0035869(ciliary transition zone);GO:0001822(kidney development);GO:0042073(intraciliary transport);GO:0001933(negative regulation of protein phosphorylation);GO:0001738(morphogenesis of a polarized epithelium);GO:0031333(negative regulation of protein complex assembly);GO:0032480(negative regulation of type I interferon production);GO:0050687(negative regulation of defense response to virus);GO:0021532(neural tube patterning);GO:0031076(embryonic camera-type eye development);GO:0032688(negative regulation of interferon-beta production);GO:0035050(embryonic heart tube development);GO:0036342(post-anal tail morphogenesis);GO:0042733(embryonic digit morphogenesis);GO:1901621(negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning);GO:0005930(axoneme);GO:0036064(ciliary basal body);GO:0036064(ciliary basal body)","NA","NA","NA","TRAF3 interacting protein 1 [Source:HGNC Symbol;Acc:HGNC:17861]",{"v":1.07772233788174,"d":"1.08"},{"v":0.363127286333117,"d":"0.36"},{"v":2.9678913660404,"d":"2.97"},{"v":1.56943828584582,"d":"1.57"},{"v":0.0563100357773272,"d":"0.06"},{"v":0.540060170751927,"d":"0.54"},"up","no"]
["ENSG00000185480","PARPBP","ENST00000541394;ENST00000457614;ENST00000327680","GO:0005654(nucleoplasm);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0003677(DNA binding);GO:0006281(DNA repair);GO:0006974(cellular response to DNA damage stimulus);GO:0005515(protein binding);GO:0000785(chromatin);GO:2000042(negative regulation of double-strand break repair via homologous recombination);GO:2000042(negative regulation of double-strand break repair via homologous recombination)","NA","NA","NA","PARP1 binding protein [Source:HGNC Symbol;Acc:HGNC:26074]",{"v":0.156654317386723,"d":"0.16"},{"v":0.337377630347734,"d":"0.34"},{"v":0.464329295410783,"d":"0.46"},{"v":-1.10677978876082,"d":"-1.11"},{"v":0.0563294288833378,"d":"0.06"},{"v":0.540060170751927,"d":"0.54"},"down","no"]
["MSTRG.4339","FBXO33","ENST00000298097","GO:0016567(protein ubiquitination);GO:0005515(protein binding)","NA","NA","NA","F-box protein 33 [Source:HGNC Symbol;Acc:HGNC:19833]",{"v":6.400907,"d":"6.40"},{"v":2.195919,"d":"2.20"},{"v":2.91491034049981,"d":"2.91"},{"v":1.54345150836381,"d":"1.54"},{"v":0.0563800828842171,"d":"0.06"},{"v":0.540060170751927,"d":"0.54"},"up","no"]
["MSTRG.9664","AHCY;AL035458.2","ENST00000217426;ENST00000512005;ENST00000473516;ENST00000468908;ENST00000538132;ENST00000606061;ENST00000480653","GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0016787(hydrolase activity);GO:0004013(adenosylhomocysteinase activity);GO:0006730(one-carbon metabolic process);GO:0005515(protein binding);GO:0051287(NAD binding);GO:0042470(melanosome);GO:0070062(extracellular exosome);GO:0033353(S-adenosylmethionine cycle);GO:0032259(methylation);GO:0030554(adenyl nucleotide binding);GO:0042802(identical protein binding);GO:0000096(sulfur amino acid metabolic process);GO:0001666(response to hypoxia);GO:0002439(chronic inflammatory response to antigenic stimulus);GO:0007584(response to nutrient);GO:0019510(S-adenosylhomocysteine catabolic process);GO:0042745(circadian sleep/wake cycle);GO:0071268(homocysteine biosynthetic process);GO:0005634(nucleus);GO:0043005(neuron projection);GO:0043005(neuron projection)","00270(Cysteine and methionine metabolism);00270(Cysteine and methionine metabolism)","K01251","EC:3.3.1.1","adenosylhomocysteinase [Source:HGNC Symbol;Acc:HGNC:343]",{"v":5.00539935317742,"d":"5.01"},{"v":10.0048059201512,"d":"10.00"},{"v":0.500299495375096,"d":"0.50"},{"v":-0.999136097724073,"d":"-1.00"},{"v":0.056383255223737,"d":"0.06"},{"v":0.540060170751927,"d":"0.54"},"down","no"]
["MSTRG.4364","RPS29","ENST00000245458;ENST00000396020;ENST00000556230;ENST00000539688;ENST00000554075;ENST00000557111;ENST00000557519;ENST00000557367","GO:0006412(translation);GO:0046872(metal ion binding);GO:0030529(intracellular ribonucleoprotein complex);GO:0005622(intracellular);GO:0003735(structural constituent of ribosome);GO:0005840(ribosome);GO:0008270(zinc ion binding);GO:0022627(cytosolic small ribosomal subunit);GO:0005925(focal adhesion);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0006413(translational initiation);GO:0006364(rRNA processing);GO:0000184(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay);GO:0019083(viral transcription);GO:0006614(SRP-dependent cotranslational protein targeting to membrane);GO:0015935(small ribosomal subunit);GO:0015935(small ribosomal subunit)","03010(Ribosome);03010(Ribosome)","K02980","NA","ribosomal protein S29 [Source:HGNC Symbol;Acc:HGNC:10419]",{"v":13.1302492803038,"d":"13.13"},{"v":26.2094481291183,"d":"26.21"},{"v":0.500973893674483,"d":"0.50"},{"v":-0.997192670005172,"d":"-1.00"},{"v":0.0564091014646474,"d":"0.06"},{"v":0.540060170751927,"d":"0.54"},"down","no"]
["ENSG00000180543","TSPYL5","ENST00000322128","GO:0005634(nucleus);GO:0006334(nucleosome assembly);GO:0005515(protein binding);GO:0040008(regulation of growth);GO:0031398(positive regulation of protein ubiquitination);GO:0008284(positive regulation of cell proliferation);GO:0051897(positive regulation of protein kinase B signaling);GO:0071480(cellular response to gamma radiation)","NA","NA","NA","TSPY like 5 [Source:HGNC Symbol;Acc:HGNC:29367]",{"v":0.744384,"d":"0.74"},{"v":0.246151,"d":"0.25"},{"v":3.02409496609805,"d":"3.02"},{"v":1.59650344543447,"d":"1.60"},{"v":0.0564329736120557,"d":"0.06"},{"v":0.540060170751927,"d":"0.54"},"up","no"]
["MSTRG.8997","MRPL30;LIPT1;AC092587.1;AC079447.1;C2orf15","ENST00000338148;ENST00000449211;ENST00000410042;ENST00000480170;ENST00000473743;ENST00000424491;ENST00000465095;ENST00000496794;ENST00000415142;ENST00000302513;ENST00000465432;ENST00000393473;ENST00000409145;ENST00000409684;ENST00000434566;ENST00000436234;ENST00000393471","GO:0030529(intracellular ribonucleoprotein complex);GO:0003735(structural constituent of ribosome);GO:0006412(translation);GO:0005840(ribosome);GO:0005739(mitochondrion);GO:0015934(large ribosomal subunit);GO:0005743(mitochondrial inner membrane);GO:0070125(mitochondrial translational elongation);GO:0070126(mitochondrial translational termination);GO:0005762(mitochondrial large ribosomal subunit);GO:0016740(transferase activity);GO:0016746(transferase activity, transferring acyl groups);GO:0006464(cellular protein modification process);GO:0005759(mitochondrial matrix);GO:0009249(protein lipoylation);GO:0034641(cellular nitrogen compound metabolic process);GO:0006629(lipid metabolic process);GO:0016979(lipoate-protein ligase activity);GO:0003723(RNA binding);GO:0016979(lipoate-protein ligase activity)","03010(Ribosome);00785(Lipoic acid metabolism);00785(Lipoic acid metabolism)","K02907;K10105","NA","mitochondrial ribosomal protein L30 [Source:HGNC Symbol;Acc:HGNC:14036];lipoyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:29569];chromosome 2 open reading frame 15 [Source:HGNC Symbol;Acc:HGNC:28436]",{"v":0.738149087503081,"d":"0.74"},{"v":1.48836723317722,"d":"1.49"},{"v":0.495945537531993,"d":"0.50"},{"v":-1.01174639574013,"d":"-1.01"},{"v":0.0564983387536525,"d":"0.06"},{"v":0.540060170751927,"d":"0.54"},"down","no"]
["MSTRG.7992","ELL","ENST00000262809;ENST00000608165;ENST00000596124;ENST00000610152;ENST00000596915;ENST00000594635","GO:0005634(nucleus);GO:0016607(nuclear speck);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0006366(transcription from RNA polymerase II promoter);GO:0006368(transcription elongation from RNA polymerase II promoter);GO:0005515(protein binding);GO:0008023(transcription elongation factor complex);GO:0005654(nucleoplasm);GO:0019902(phosphatase binding);GO:0010923(negative regulation of phosphatase activity);GO:0042795(snRNA transcription from RNA polymerase II promoter);GO:0015030(Cajal body);GO:0032968(positive regulation of transcription elongation from RNA polymerase II promoter);GO:0035327(transcriptionally active chromatin);GO:0045945(positive regulation of transcription from RNA polymerase III promoter);GO:0032786(positive regulation of DNA-templated transcription, elongation);GO:0001701(in utero embryonic development);GO:0042796(snRNA transcription from RNA polymerase III promoter);GO:0035363(histone locus body);GO:0035363(histone locus body)","NA","NA","NA","elongation factor for RNA polymerase II [Source:HGNC Symbol;Acc:HGNC:23114]",{"v":9.20780061614932,"d":"9.21"},{"v":3.16955891438426,"d":"3.17"},{"v":2.90507318679643,"d":"2.91"},{"v":1.53857450955003,"d":"1.54"},{"v":0.0565738560740806,"d":"0.06"},{"v":0.540060170751927,"d":"0.54"},"up","no"]
["MSTRG.5490","FBXL16","ENST00000562563;ENST00000562585;ENST00000397621;ENST00000562648","GO:0005829(cytosol);GO:0000209(protein polyubiquitination);GO:0043687(post-translational protein modification);GO:0004842(ubiquitin-protein transferase activity);GO:0005737(cytoplasm);GO:0005737(cytoplasm)","NA","NA","NA","F-box and leucine rich repeat protein 16 [Source:HGNC Symbol;Acc:HGNC:14150]",{"v":0.730705845073953,"d":"0.73"},{"v":0.243284655051391,"d":"0.24"},{"v":3.00350157686517,"d":"3.00"},{"v":1.58664542129237,"d":"1.59"},{"v":0.0566072017080486,"d":"0.06"},{"v":0.540060170751927,"d":"0.54"},"up","no"]
["MSTRG.11153","ZXDC","ENST00000336332;ENST00000514463;ENST00000389709;ENST00000515545","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0005515(protein binding);GO:0045893(positive regulation of transcription, DNA-templated);GO:0005575(cellular_component);GO:0070742(C2H2 zinc finger domain binding);GO:0030275(LRR domain binding);GO:0030275(LRR domain binding)","NA","NA","NA","ZXD family zinc finger C [Source:HGNC Symbol;Acc:HGNC:28160]",{"v":3.84795238099769,"d":"3.85"},{"v":1.32125787331793,"d":"1.32"},{"v":2.91234017121484,"d":"2.91"},{"v":1.54217887705521,"d":"1.54"},{"v":0.0566113156326012,"d":"0.06"},{"v":0.540060170751927,"d":"0.54"},"up","no"]
["MSTRG.1925","NPM3","ENST00000370110;ENST00000468544;ENST00000474993","GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005730(nucleolus);GO:0005829(cytosol);GO:0015629(actin cytoskeleton);GO:0005515(protein binding);GO:0006364(rRNA processing);GO:0009303(rRNA transcription);GO:0009303(rRNA transcription)","NA","NA","NA","nucleophosmin/nucleoplasmin 3 [Source:HGNC Symbol;Acc:HGNC:7931]",{"v":3.52671228556034,"d":"3.53"},{"v":7.16288793965517,"d":"7.16"},{"v":0.492358991969672,"d":"0.49"},{"v":-1.02221748851929,"d":"-1.02"},{"v":0.0566375693193498,"d":"0.06"},{"v":0.540060170751927,"d":"0.54"},"down","no"]
["ENSG00000068489","PRR11","ENST00000262293;ENST00000578777;ENST00000578542","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0051726(regulation of cell cycle);GO:0007050(cell cycle arrest);GO:0007050(cell cycle arrest)","NA","NA","NA","proline rich 11 [Source:HGNC Symbol;Acc:HGNC:25619]",{"v":0.799146998039216,"d":"0.80"},{"v":0.263044815686274,"d":"0.26"},{"v":3.03806404986265,"d":"3.04"},{"v":1.60315228572056,"d":"1.60"},{"v":0.0566519892140543,"d":"0.06"},{"v":0.540060170751927,"d":"0.54"},"up","no"]
["MSTRG.11896","FTH1P21","MSTRG.11896.1","NA","NA","NA","NA",null,{"v":4.461504,"d":"4.46"},{"v":9.030972,"d":"9.03"},{"v":0.494022570327978,"d":"0.49"},{"v":-1.01735113940048,"d":"-1.02"},{"v":0.0568105540020115,"d":"0.06"},{"v":0.540060170751927,"d":"0.54"},"down","no"]
["ENSG00000100362","PVALB","ENST00000417718;ENST00000467935;ENST00000406910","GO:0046872(metal ion binding);GO:0005509(calcium ion binding);GO:0070062(extracellular exosome);GO:0042803(protein homodimerization activity);GO:0046982(protein heterodimerization activity);GO:0051480(regulation of cytosolic calcium ion concentration);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0030424(axon);GO:0043025(neuronal cell body);GO:0043195(terminal bouton);GO:0043234(protein complex);GO:0043234(protein complex)","NA","NA","NA","parvalbumin [Source:HGNC Symbol;Acc:HGNC:9704]",{"v":1.1585509352381,"d":"1.16"},{"v":2.39375667809524,"d":"2.39"},{"v":0.48398859660205,"d":"0.48"},{"v":-1.04695503875006,"d":"-1.05"},{"v":0.0568718399343687,"d":"0.06"},{"v":0.540060170751927,"d":"0.54"},"down","no"]
["ENSG00000143324","XPR1","ENST00000367590;ENST00000367589;ENST00000464817","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005886(plasma membrane);GO:0004872(receptor activity);GO:0009615(response to virus);GO:0005737(cytoplasm);GO:0046718(viral entry into host cell);GO:0004930(G-protein coupled receptor activity);GO:0007186(G-protein coupled receptor signaling pathway);GO:0031226(intrinsic component of plasma membrane);GO:0015562(efflux transmembrane transporter activity);GO:0004888(transmembrane signaling receptor activity);GO:0001618(virus receptor activity);GO:0035435(phosphate ion transmembrane transport);GO:0030643(cellular phosphate ion homeostasis);GO:0000822(inositol hexakisphosphate binding);GO:0015114(phosphate ion transmembrane transporter activity);GO:0015114(phosphate ion transmembrane transporter activity)","NA","NA","NA","xenotropic and polytropic retrovirus receptor 1 [Source:HGNC Symbol;Acc:HGNC:12827]",{"v":2.27893633292149,"d":"2.28"},{"v":0.781718375603729,"d":"0.78"},{"v":2.91529072878893,"d":"2.92"},{"v":1.54363976406634,"d":"1.54"},{"v":0.0568782165071758,"d":"0.06"},{"v":0.540060170751927,"d":"0.54"},"up","no"]
["MSTRG.2600","AIP","ENST00000279146;ENST00000525341;ENST00000528641;ENST00000529797","GO:0016853(isomerase activity);GO:0005829(cytosol);GO:0003755(peptidyl-prolyl cis-trans isomerase activity);GO:0000413(protein peptidyl-prolyl isomerization);GO:0005737(cytoplasm);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:1903506(regulation of nucleic acid-templated transcription);GO:0005654(nucleoplasm);GO:0006805(xenobiotic metabolic process);GO:0003712(transcription cofactor activity);GO:0017162(aryl hydrocarbon receptor binding);GO:0010738(regulation of protein kinase A signaling);GO:0051344(negative regulation of cyclic-nucleotide phosphodiesterase activity);GO:0016020(membrane);GO:0034751(aryl hydrocarbon receptor complex);GO:0003713(transcription coactivator activity);GO:0004871(signal transducer activity);GO:0008134(transcription factor binding);GO:0036004(GAF domain binding);GO:0051082(unfolded protein binding);GO:0006626(protein targeting to mitochondrion);GO:0022417(protein maturation by protein folding);GO:0035722(interleukin-12-mediated signaling pathway);GO:0035722(interleukin-12-mediated signaling pathway)","NA","NA","NA","aryl hydrocarbon receptor interacting protein [Source:HGNC Symbol;Acc:HGNC:358]",{"v":18.3245804109756,"d":"18.32"},{"v":36.5690752969512,"d":"36.57"},{"v":0.501094989746797,"d":"0.50"},{"v":-0.996843981992324,"d":"-1.00"},{"v":0.0569232251505565,"d":"0.06"},{"v":0.540060170751927,"d":"0.54"},"down","no"]
["MSTRG.3784","POP5","ENST00000357500;ENST00000539716;ENST00000542568;ENST00000341039;ENST00000535245;ENST00000541834;ENST00000511394;ENST00000542776","GO:0005634(nucleus);GO:0008033(tRNA processing);GO:0016787(hydrolase activity);GO:0005515(protein binding);GO:0016070(RNA metabolic process);GO:0090501(RNA phosphodiester bond hydrolysis);GO:0090502(RNA phosphodiester bond hydrolysis, endonucleolytic);GO:0005730(nucleolus);GO:0004540(ribonuclease activity);GO:0005654(nucleoplasm);GO:0009249(protein lipoylation);GO:0004526(ribonuclease P activity);GO:0001682(tRNA 5'-leader removal);GO:0000172(ribonuclease MRP complex);GO:0030681(multimeric ribonuclease P complex);GO:0005655(nucleolar ribonuclease P complex);GO:0005655(nucleolar ribonuclease P complex)","03013(RNA transport);03008(Ribosome biogenesis in eukaryotes);03008(Ribosome biogenesis in eukaryotes)","K03537","EC:3.1.26.5","POP5 homolog, ribonuclease P/MRP subunit [Source:HGNC Symbol;Acc:HGNC:17689]",{"v":1.94767784491486,"d":"1.95"},{"v":3.93224070593649,"d":"3.93"},{"v":0.495309923925679,"d":"0.50"},{"v":-1.01359656809042,"d":"-1.01"},{"v":0.0569245855300792,"d":"0.06"},{"v":0.540060170751927,"d":"0.54"},"down","no"]
["ENSG00000197386","HTT","ENST00000355072;ENST00000509043;ENST00000512909;ENST00000512068;ENST00000502820;ENST00000506137;ENST00000510626;ENST00000513326;ENST00000509751;ENST00000513639;ENST00000508321","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0005794(Golgi apparatus);GO:0005783(endoplasmic reticulum);GO:0005515(protein binding);GO:0006915(apoptotic process);GO:0030659(cytoplasmic vesicle membrane);GO:0030425(dendrite);GO:0042802(identical protein binding);GO:0045505(dynein intermediate chain binding);GO:0030424(axon);GO:0008134(transcription factor binding);GO:0006890(retrograde vesicle-mediated transport, Golgi to ER);GO:0044325(ion channel binding);GO:0043234(protein complex);GO:0005770(late endosome);GO:0005776(autophagosome);GO:0048513(animal organ development);GO:0047496(vesicle transport along microtubule);GO:0048487(beta-tubulin binding);GO:0000132(establishment of mitotic spindle orientation);GO:0007030(Golgi organization);GO:0002039(p53 binding);GO:2001237(negative regulation of extrinsic apoptotic signaling pathway);GO:0043065(positive regulation of apoptotic process);GO:1903599(positive regulation of mitophagy);GO:0031072(heat shock protein binding);GO:0048471(perinuclear region of cytoplasm);GO:0031648(protein destabilization);GO:0016234(inclusion body);GO:0019900(kinase binding);GO:0005522(profilin binding);GO:0034452(dynactin binding);GO:0031587(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity);GO:0042297(vocal learning);GO:0043666(regulation of phosphoprotein phosphatase activity);GO:0045724(positive regulation of cilium assembly);GO:1904504(positive regulation of lipophagy);GO:1905337(positive regulation of aggrephagy);GO:0005814(centriole);GO:0005814(centriole)","05016(Huntington's disease);05016(Huntington's disease)","K04533","NA","huntingtin [Source:HGNC Symbol;Acc:HGNC:4851]",{"v":4.3070283733451,"d":"4.31"},{"v":1.48626339612754,"d":"1.49"},{"v":2.89789036355673,"d":"2.90"},{"v":1.53500301416847,"d":"1.54"},{"v":0.0569813299657483,"d":"0.06"},{"v":0.540060170751927,"d":"0.54"},"up","no"]
["MSTRG.7021","MRPL27","ENST00000225969;ENST00000442592;ENST00000511860;ENST00000507088;ENST00000503633;ENST00000514928;ENST00000508200","GO:0005622(intracellular);GO:0003735(structural constituent of ribosome);GO:0006412(translation);GO:0005840(ribosome);GO:0003723(RNA binding);GO:0030529(intracellular ribonucleoprotein complex);GO:0005739(mitochondrion);GO:0005515(protein binding);GO:0005743(mitochondrial inner membrane);GO:0070125(mitochondrial translational elongation);GO:0070126(mitochondrial translational termination);GO:0005762(mitochondrial large ribosomal subunit);GO:0005762(mitochondrial large ribosomal subunit)","03010(Ribosome);03010(Ribosome)","K02899","NA","mitochondrial ribosomal protein L27 [Source:HGNC Symbol;Acc:HGNC:14483]",{"v":0.939178205483978,"d":"0.94"},{"v":1.9270115546746,"d":"1.93"},{"v":0.487375492485083,"d":"0.49"},{"v":-1.03689438744362,"d":"-1.04"},{"v":0.0570357336832201,"d":"0.06"},{"v":0.540060170751927,"d":"0.54"},"down","no"]
["MSTRG.14027","TRBV2","ENST00000455382","NA","NA","NA","NA","T-cell receptor beta variable 2 [Source:HGNC Symbol;Acc:HGNC:12195]",{"v":5.328113,"d":"5.33"},{"v":10.887274,"d":"10.89"},{"v":0.489389079396734,"d":"0.49"},{"v":-1.03094618651452,"d":"-1.03"},{"v":0.0570623934884879,"d":"0.06"},{"v":0.540060170751927,"d":"0.54"},"down","no"]
["ENSG00000135966","TGFBRAP1","ENST00000595531;ENST00000258449;ENST00000393359","GO:0006810(transport);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0006886(intracellular protein transport);GO:0015031(protein transport);GO:0016192(vesicle-mediated transport);GO:0043231(intracellular membrane-bounded organelle);GO:0006355(regulation of transcription, DNA-templated);GO:0005515(protein binding);GO:0007165(signal transduction);GO:0005768(endosome);GO:0008333(endosome to lysosome transport);GO:0005769(early endosome);GO:0007179(transforming growth factor beta receptor signaling pathway);GO:0046332(SMAD binding);GO:0034058(endosomal vesicle fusion);GO:0005160(transforming growth factor beta receptor binding);GO:0033263(CORVET complex);GO:0033263(CORVET complex)","NA","NA","NA","transforming growth factor beta receptor associated protein 1 [Source:HGNC Symbol;Acc:HGNC:16836]",{"v":3.45872414537885,"d":"3.46"},{"v":1.18790425112406,"d":"1.19"},{"v":2.91161862760068,"d":"2.91"},{"v":1.54182139945785,"d":"1.54"},{"v":0.05706579302479,"d":"0.06"},{"v":0.540060170751927,"d":"0.54"},"up","no"]
["MSTRG.7106","PRKCA","ENST00000413366;ENST00000284384;ENST00000578063;ENST00000583361","GO:0005622(intracellular);GO:0046872(metal ion binding);GO:0035556(intracellular signal transduction);GO:0007194(negative regulation of adenylate cyclase activity);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0008270(zinc ion binding);GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0005829(cytosol);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0007155(cell adhesion);GO:0005886(plasma membrane);GO:0005739(mitochondrion);GO:0005515(protein binding);GO:0006915(apoptotic process);GO:0004697(protein kinase C activity);GO:0048471(perinuclear region of cytoplasm);GO:0031966(mitochondrial membrane);GO:0005654(nucleoplasm);GO:0070062(extracellular exosome);GO:0043488(regulation of mRNA stability);GO:0030335(positive regulation of cell migration);GO:0018105(peptidyl-serine phosphorylation);GO:0005783(endoplasmic reticulum);GO:0070374(positive regulation of ERK1 and ERK2 cascade);GO:0045785(positive regulation of cell adhesion);GO:0030168(platelet activation);GO:0007411(axon guidance);GO:0001525(angiogenesis);GO:0034351(negative regulation of glial cell apoptotic process);GO:0050796(regulation of insulin secretion);GO:0038128(ERBB2 signaling pathway);GO:0045766(positive regulation of angiogenesis);GO:0019899(enzyme binding);GO:0010595(positive regulation of endothelial cell migration);GO:0007077(mitotic nuclear envelope disassembly);GO:0070555(response to interleukin-1);GO:0001938(positive regulation of endothelial cell proliferation);GO:0097190(apoptotic signaling pathway);GO:0045931(positive regulation of mitotic cell cycle);GO:0010613(positive regulation of cardiac muscle hypertrophy);GO:0007190(activation of adenylate cyclase activity);GO:0004698(calcium-dependent protein kinase C activity);GO:0035403(histone kinase activity (H3-T6 specific));GO:0035408(histone H3-T6 phosphorylation);GO:0045651(positive regulation of macrophage differentiation);GO:0090330(regulation of platelet aggregation);GO:0043536(positive regulation of blood vessel endothelial cell migration);GO:2000707(positive regulation of dense core granule biogenesis);GO:0002159(desmosome assembly);GO:0031666(positive regulation of lipopolysaccharide-mediated signaling pathway);GO:0031666(positive regulation of lipopolysaccharide-mediated signaling pathway)","04014(Ras signaling pathway);04015(Rap1 signaling pathway);04010(MAPK signaling pathway);04012(ErbB signaling pathway);04310(Wnt signaling pathway);04370(VEGF signaling pathway);04066(HIF-1 signaling pathway);04020(Calcium signaling pathway);04070(Phosphatidylinositol signaling system);04072(Phospholipase D signaling pathway);04071(Sphingolipid signaling pathway);04151(PI3K-Akt signaling pathway);04150(mTOR signaling pathway);04510(Focal adhesion);04540(Gap junction);04650(Natural killer cell mediated cytotoxicity);04664(Fc epsilon RI signaling pathway);04666(Fc gamma R-mediated phagocytosis);04670(Leukocyte transendothelial migration);04911(Insulin secretion);04912(GnRH signaling pathway);04921(Oxytocin signaling pathway);04926(Relaxin signaling pathway);04918(Thyroid hormone synthesis);04919(Thyroid hormone signaling pathway);04916(Melanogenesis);04925(Aldosterone synthesis and secretion);04261(Adrenergic signaling in cardiomyocytes);04270(Vascular smooth muscle contraction);04970(Salivary secretion);04971(Gastric acid secretion);04972(Pancreatic secretion);04960(Aldosterone-regulated sodium reabsorption);04961(Endocrine and other factor-regulated calcium reabsorption);04724(Glutamatergic synapse);04727(GABAergic synapse);04725(Cholinergic synapse);04728(Dopaminergic synapse);04726(Serotonergic synapse);04720(Long-term potentiation);04730(Long-term depression);04723(Retrograde endocannabinoid signaling);04750(Inflammatory mediator regulation of TRP channels);04360(Axon guidance);04713(Circadian entrainment);05200(Pathways in cancer);05231(Choline metabolism in cancer);05206(MicroRNAs in cancer);05205(Proteoglycans in cancer);05225(Hepatocellular carcinoma);05214(Glioma);05223(Non-small cell lung cancer);05031(Amphetamine addiction);05032(Morphine addiction);04933(AGE-RAGE signaling pathway in diabetic complications);05110(Vibrio cholerae infection);05130(Pathogenic Escherichia coli infection);05164(Influenza A);05161(Hepatitis B);05146(Amoebiasis);05143(African trypanosomiasis);01521(EGFR tyrosine kinase inhibitor resistance);01521(EGFR tyrosine kinase inhibitor resistance)","K02677","EC:2.7.11.13","protein kinase C alpha [Source:HGNC Symbol;Acc:HGNC:9393]",{"v":3.41513111217719,"d":"3.42"},{"v":1.17820499264706,"d":"1.18"},{"v":2.89858821978377,"d":"2.90"},{"v":1.535350395327,"d":"1.54"},{"v":0.0571078868236774,"d":"0.06"},{"v":0.540060170751927,"d":"0.54"},"up","no"]
["ENSG00000204138","PHACTR4","ENST00000373839;ENST00000632421;ENST00000633371;ENST00000632202;ENST00000493669;ENST00000373836;ENST00000463428","GO:0005737(cytoplasm);GO:0003779(actin binding);GO:0042995(cell projection);GO:0007275(multicellular organism development);GO:0007399(nervous system development);GO:0019888(protein phosphatase regulator activity);GO:0008157(protein phosphatase 1 binding);GO:0030027(lamellipodium);GO:0051726(regulation of cell cycle);GO:0030036(actin cytoskeleton organization);GO:0007266(Rho protein signal transduction);GO:0001843(neural tube closure);GO:0001755(neural crest cell migration);GO:0072542(protein phosphatase activator activity);GO:0043085(positive regulation of catalytic activity);GO:0061386(closure of optic fissure);GO:0048484(enteric nervous system development);GO:2001045(negative regulation of integrin-mediated signaling pathway);GO:0050790(regulation of catalytic activity);GO:0043086(negative regulation of catalytic activity);GO:0004864(protein phosphatase inhibitor activity);GO:0005622(intracellular);GO:0005622(intracellular)","NA","NA","NA","phosphatase and actin regulator 4 [Source:HGNC Symbol;Acc:HGNC:25793]",{"v":3.14773054930347,"d":"3.15"},{"v":1.08353225457525,"d":"1.08"},{"v":2.90506400341298,"d":"2.91"},{"v":1.53856994896176,"d":"1.54"},{"v":0.0572522399466329,"d":"0.06"},{"v":0.540094215475686,"d":"0.54"},"up","no"]
["MSTRG.34","AL732372.3","ENST00000514436","NA","NA","NA","NA",null,{"v":18.569715,"d":"18.57"},{"v":6.392936,"d":"6.39"},{"v":2.90472405792894,"d":"2.90"},{"v":1.53840111744523,"d":"1.54"},{"v":0.0572872115617653,"d":"0.06"},{"v":0.540094215475686,"d":"0.54"},"up","no"]
["MSTRG.13120","OGFRL1","MSTRG.13120.2;ENST00000370435;ENST00000467503","GO:0016020(membrane);GO:0004872(receptor activity);GO:0004872(receptor activity)","NA","NA","NA","opioid growth factor receptor like 1 [Source:HGNC Symbol;Acc:HGNC:21378]",{"v":32.7588106601502,"d":"32.76"},{"v":11.335269020433,"d":"11.34"},{"v":2.88998969509229,"d":"2.89"},{"v":1.53106434848175,"d":"1.53"},{"v":0.0572977419211143,"d":"0.06"},{"v":0.540094215475686,"d":"0.54"},"up","no"]
["MSTRG.8971","TMEM127","ENST00000258439;ENST00000432959;ENST00000435268","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0032007(negative regulation of TOR signaling);GO:0005886(plasma membrane);GO:0008285(negative regulation of cell proliferation);GO:0003674(molecular_function);GO:0017137(Rab GTPase binding);GO:0007032(endosome organization);GO:0032006(regulation of TOR signaling);GO:0005769(early endosome);GO:0005769(early endosome)","NA","NA","NA","transmembrane protein 127 [Source:HGNC Symbol;Acc:HGNC:26038]",{"v":2.91586937757185,"d":"2.92"},{"v":5.81531248657138,"d":"5.82"},{"v":0.501412328968585,"d":"0.50"},{"v":-0.995930624596726,"d":"-1.00"},{"v":0.0573746272876492,"d":"0.06"},{"v":0.540094215475686,"d":"0.54"},"down","no"]
["MSTRG.10534","NFAM1","ENST00000329021;ENST00000355469","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005886(plasma membrane);GO:0004888(transmembrane signaling receptor activity);GO:0007166(cell surface receptor signaling pathway);GO:0043312(neutrophil degranulation);GO:0001819(positive regulation of cytokine production);GO:0045577(regulation of B cell differentiation);GO:0050861(positive regulation of B cell receptor signaling pathway);GO:0035577(azurophil granule membrane);GO:0035556(intracellular signal transduction);GO:0006954(inflammatory response);GO:0007165(signal transduction);GO:0051091(positive regulation of sequence-specific DNA binding transcription factor activity);GO:0030183(B cell differentiation);GO:0050853(B cell receptor signaling pathway);GO:0009986(cell surface);GO:0045121(membrane raft);GO:0045121(membrane raft)","NA","NA","NA","NFAT activating protein with ITAM motif 1 [Source:HGNC Symbol;Acc:HGNC:29872]",{"v":57.4743541830841,"d":"57.47"},{"v":19.8990770871583,"d":"19.90"},{"v":2.88829245353166,"d":"2.89"},{"v":1.53021682944749,"d":"1.53"},{"v":0.0574143702051871,"d":"0.06"},{"v":0.540094215475686,"d":"0.54"},"up","no"]
["ENSG00000214113","LYRM4","ENST00000500576;ENST00000330636;ENST00000458438;ENST00000464010;ENST00000480566;ENST00000463032","GO:0005634(nucleus);GO:0005739(mitochondrion);GO:0016604(nuclear body);GO:0005759(mitochondrial matrix);GO:0044281(small molecule metabolic process);GO:0044281(small molecule metabolic process)","NA","NA","NA","LYR motif containing 4 [Source:HGNC Symbol;Acc:HGNC:21365]",{"v":0.782597886264958,"d":"0.78"},{"v":1.56625943418405,"d":"1.57"},{"v":0.499660445252262,"d":"0.50"},{"v":-1.00098008073009,"d":"-1.00"},{"v":0.0574418293475717,"d":"0.06"},{"v":0.540094215475686,"d":"0.54"},"down","no"]
["ENSG00000116661","FBXO2","ENST00000354287;ENST00000466919;ENST00000465901;ENST00000471501;ENST00000642025","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0030246(carbohydrate binding);GO:0016567(protein ubiquitination);GO:0005829(cytosol);GO:0005783(endoplasmic reticulum);GO:0005515(protein binding);GO:0043231(intracellular membrane-bounded organelle);GO:0070062(extracellular exosome);GO:0000209(protein polyubiquitination);GO:0043687(post-translational protein modification);GO:0031090(organelle membrane);GO:0004842(ubiquitin-protein transferase activity);GO:0006464(cellular protein modification process);GO:0006508(proteolysis);GO:0019005(SCF ubiquitin ligase complex);GO:0031146(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process);GO:0006516(glycoprotein catabolic process);GO:0001540(amyloid-beta binding);GO:0006511(ubiquitin-dependent protein catabolic process);GO:0008285(negative regulation of cell proliferation);GO:0030433(ubiquitin-dependent ERAD pathway);GO:0031396(regulation of protein ubiquitination);GO:0043197(dendritic spine);GO:0043197(dendritic spine)","04141(Protein processing in endoplasmic reticulum);04120(Ubiquitin mediated proteolysis);04120(Ubiquitin mediated proteolysis)","K10099","NA","F-box protein 2 [Source:HGNC Symbol;Acc:HGNC:13581]",{"v":0.252125650761124,"d":"0.25"},{"v":0.538402306791569,"d":"0.54"},{"v":0.468284863531852,"d":"0.47"},{"v":-1.09454168862586,"d":"-1.09"},{"v":0.057469443852309,"d":"0.06"},{"v":0.540094215475686,"d":"0.54"},"down","no"]
["MSTRG.12988","BRPF3","ENST00000357641;ENST00000449261;ENST00000454960;ENST00000532538;ENST00000441123;ENST00000527657;ENST00000441730","GO:0046872(metal ion binding);GO:0016569(covalent chromatin modification);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0005829(cytosol);GO:0002576(platelet degranulation);GO:0043966(histone H3 acetylation);GO:0070776(MOZ/MORF histone acetyltransferase complex);GO:0070776(MOZ/MORF histone acetyltransferase complex)","NA","NA","NA","bromodomain and PHD finger containing 3 [Source:HGNC Symbol;Acc:HGNC:14256]",{"v":6.08063103175563,"d":"6.08"},{"v":2.09875357734765,"d":"2.10"},{"v":2.89725820953224,"d":"2.90"},{"v":1.53468826624843,"d":"1.53"},{"v":0.0574835486375569,"d":"0.06"},{"v":0.540094215475686,"d":"0.54"},"up","no"]
["MSTRG.13982","BPGM","ENST00000344924;ENST00000393132;ENST00000443095;ENST00000418040","GO:0016853(isomerase activity);GO:0016787(hydrolase activity);GO:0003824(catalytic activity);GO:0006096(glycolytic process);GO:0008152(metabolic process);GO:0004082(bisphosphoglycerate mutase activity);GO:0004619(phosphoglycerate mutase activity);GO:0016868(intramolecular transferase activity, phosphotransferases);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0005975(carbohydrate metabolic process);GO:0006094(gluconeogenesis);GO:0061621(canonical glycolysis);GO:0007585(respiratory gaseous exchange);GO:0046538(2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity);GO:0043456(regulation of pentose-phosphate shunt);GO:0043456(regulation of pentose-phosphate shunt)","00010(Glycolysis / Gluconeogenesis);00260(Glycine, serine and threonine metabolism);00260(Glycine, serine and threonine metabolism)","K01837","EC:5.4.2.4;EC:5.4.2.11","bisphosphoglycerate mutase [Source:HGNC Symbol;Acc:HGNC:1093]",{"v":4.50569576053564,"d":"4.51"},{"v":8.99727067191808,"d":"9.00"},{"v":0.50078472959568,"d":"0.50"},{"v":-0.997737523975595,"d":"-1.00"},{"v":0.0576494383469085,"d":"0.06"},{"v":0.541110067005541,"d":"0.54"},"down","no"]
["ENSG00000156384","SFR1","ENST00000369729;ENST00000369727;ENST00000463224","GO:0005634(nucleus);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0005515(protein binding);GO:0006281(DNA repair);GO:0006974(cellular response to DNA damage stimulus);GO:0030374(ligand-dependent nuclear receptor transcription coactivator activity);GO:0045893(positive regulation of transcription, DNA-templated);GO:0000724(double-strand break repair via homologous recombination);GO:0071391(cellular response to estrogen stimulus);GO:0032798(Swi5-Sfr1 complex);GO:0032798(Swi5-Sfr1 complex)","NA","NA","NA","SWI5 dependent homologous recombination repair protein 1 [Source:HGNC Symbol;Acc:HGNC:29574]",{"v":0.879990001655629,"d":"0.88"},{"v":1.80652490011038,"d":"1.81"},{"v":0.487117560129872,"d":"0.49"},{"v":-1.0376581029723,"d":"-1.04"},{"v":0.0576848586026746,"d":"0.06"},{"v":0.541110067005541,"d":"0.54"},"down","no"]
["ENSG00000163684","RPP14","ENST00000445193;ENST00000463550;ENST00000466547;ENST00000295959","GO:0005634(nucleus);GO:0008033(tRNA processing);GO:0016787(hydrolase activity);GO:0090501(RNA phosphodiester bond hydrolysis);GO:0090502(RNA phosphodiester bond hydrolysis, endonucleolytic);GO:0004540(ribonuclease activity);GO:0005654(nucleoplasm);GO:0003723(RNA binding);GO:0006364(rRNA processing);GO:0004526(ribonuclease P activity);GO:0001682(tRNA 5'-leader removal);GO:0030681(multimeric ribonuclease P complex);GO:0030681(multimeric ribonuclease P complex)","03013(RNA transport);03013(RNA transport)","K14529","EC:3.1.26.5","ribonuclease P/MRP subunit p14 [Source:HGNC Symbol;Acc:HGNC:30327]",{"v":0.322776880343922,"d":"0.32"},{"v":0.655951838786721,"d":"0.66"},{"v":0.492074053700261,"d":"0.49"},{"v":-1.02305264748012,"d":"-1.02"},{"v":0.0577443967009412,"d":"0.06"},{"v":0.541231379247805,"d":"0.54"},"down","no"]
["MSTRG.12319","TCF7","ENST00000395023;MSTRG.12319.1;ENST00000522653;ENST00000520958;ENST00000342854;MSTRG.12319.4;ENST00000519165;ENST00000378560;ENST00000517478;ENST00000524342;ENST00000522375;ENST00000521970;ENST00000517851;ENST00000521639;ENST00000519037;ENST00000519238;ENST00000395029;ENST00000519447;ENST00000517741;ENST00000518887;ENST00000517799;ENST00000520652;ENST00000522561","GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0008013(beta-catenin binding);GO:0060070(canonical Wnt signaling pathway);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0016604(nuclear body);GO:0016055(Wnt signaling pathway);GO:0005667(transcription factor complex);GO:0033153(T cell receptor V(D)J recombination);GO:0006955(immune response);GO:0044212(transcription regulatory region DNA binding);GO:1904837(beta-catenin-TCF complex assembly);GO:0043565(sequence-specific DNA binding);GO:0071353(cellular response to interleukin-4);GO:0001047(core promoter binding);GO:0001227(transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0021915(neural tube development);GO:0030538(embryonic genitalia morphogenesis);GO:0042127(regulation of cell proliferation);GO:0044336(canonical Wnt signaling pathway involved in negative regulation of apoptotic process);GO:0046632(alpha-beta T cell differentiation);GO:0048557(embryonic digestive tract morphogenesis);GO:0048619(embryonic hindgut morphogenesis);GO:0005719(nuclear euchromatin);GO:0005719(nuclear euchromatin)","04310(Wnt signaling pathway);04390(Hippo signaling pathway);04520(Adherens junction);04916(Melanogenesis);05200(Pathways in cancer);05210(Colorectal cancer);05225(Hepatocellular carcinoma);05226(Gastric cancer);05216(Thyroid cancer);05221(Acute myeloid leukemia);05217(Basal cell carcinoma);05215(Prostate cancer);05213(Endometrial cancer);05224(Breast cancer);05412(Arrhythmogenic right ventricular cardiomyopathy (ARVC));05165(Human papillomavirus infection);05165(Human papillomavirus infection)","K02620","NA","transcription factor 7 [Source:HGNC Symbol;Acc:HGNC:11639]",{"v":6.65986573489676,"d":"6.66"},{"v":2.30352309355085,"d":"2.30"},{"v":2.89116516936267,"d":"2.89"},{"v":1.53165103088819,"d":"1.53"},{"v":0.0579151434308911,"d":"0.06"},{"v":0.54161249040336,"d":"0.54"},"up","no"]
["MSTRG.10677","TMEM43;AC093495.1;AC090004.1","ENST00000306077;ENST00000627385;ENST00000628412;ENST00000626655;ENST00000601399;ENST00000628446;ENST00000628785;ENST00000629708;ENST00000626721;ENST00000608606;ENST00000628978;ENST00000630173;ENST00000432444;ENST00000420253;ENST00000428681","GO:0005634(nucleus);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005783(endoplasmic reticulum);GO:0005515(protein binding);GO:0043621(protein self-association);GO:0071763(nuclear membrane organization);GO:0005637(nuclear inner membrane);GO:0005639(integral component of nuclear inner membrane);GO:0005788(endoplasmic reticulum lumen);GO:0005794(Golgi apparatus);GO:0005794(Golgi apparatus)","NA","NA","NA","transmembrane protein 43 [Source:HGNC Symbol;Acc:HGNC:28472]",{"v":15.9852932557722,"d":"15.99"},{"v":5.53554572293484,"d":"5.54"},{"v":2.88775381071139,"d":"2.89"},{"v":1.5299477535806,"d":"1.53"},{"v":0.0579192927968235,"d":"0.06"},{"v":0.54161249040336,"d":"0.54"},"up","no"]
["MSTRG.978","S100A4","ENST00000368715;ENST00000354332;ENST00000368716;ENST00000468373;ENST00000368714;ENST00000481009","GO:0003723(RNA binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0005509(calcium ion binding);GO:0005515(protein binding);GO:0048471(perinuclear region of cytoplasm);GO:0005615(extracellular space);GO:0046914(transition metal ion binding);GO:0070062(extracellular exosome);GO:0043123(positive regulation of I-kappaB kinase/NF-kappaB signaling);GO:0050786(RAGE receptor binding);GO:0001837(epithelial to mesenchymal transition);GO:0003779(actin binding);GO:0042802(identical protein binding);GO:0048306(calcium-dependent protein binding);GO:0043005(neuron projection);GO:0043005(neuron projection)","NA","NA","NA","S100 calcium binding protein A4 [Source:HGNC Symbol;Acc:HGNC:10494]",{"v":212.763643748293,"d":"212.76"},{"v":422.257783974634,"d":"422.26"},{"v":0.503871454412488,"d":"0.50"},{"v":-0.98887236857388,"d":"-0.99"},{"v":0.0579249731405299,"d":"0.06"},{"v":0.54161249040336,"d":"0.54"},"down","no"]
["MSTRG.9562","ZNF343;SNRPB;AL049650.1","ENST00000612935;ENST00000381342;ENST00000617391;ENST00000474384;ENST00000461548;ENST00000278772;ENST00000438552;ENST00000421216;ENST00000381253","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0005622(intracellular);GO:0005515(protein binding);GO:0003723(RNA binding);GO:0006397(mRNA processing);GO:0008380(RNA splicing);GO:0005737(cytoplasm);GO:0005654(nucleoplasm);GO:0019013(viral nucleocapsid);GO:0030529(intracellular ribonucleoprotein complex);GO:0005829(cytosol);GO:0005681(spliceosomal complex);GO:0000387(spliceosomal snRNP assembly);GO:0005685(U1 snRNP);GO:0070062(extracellular exosome);GO:0005682(U5 snRNP);GO:0046540(U4/U6 x U5 tri-snRNP complex);GO:0000398(mRNA splicing, via spliceosome);GO:0006369(termination of RNA polymerase II transcription);GO:0034709(methylosome);GO:0070034(telomerase RNA binding);GO:0005697(telomerase holoenzyme complex);GO:0051170(nuclear import);GO:0034719(SMN-Sm protein complex);GO:0071013(catalytic step 2 spliceosome);GO:0005686(U2 snRNP);GO:0071004(U2-type prespliceosome);GO:0005689(U12-type spliceosomal complex);GO:0030532(small nuclear ribonucleoprotein complex);GO:0030620(U2 snRNA binding);GO:0006479(protein methylation);GO:0008334(histone mRNA metabolic process);GO:0005683(U7 snRNP);GO:0005687(U4 snRNP);GO:0071208(histone pre-mRNA DCP binding);GO:0071204(histone pre-mRNA 3'end processing complex);GO:0005515(protein binding)","03040(Spliceosome);05322(Systemic lupus erythematosus);05322(Systemic lupus erythematosus)","K11086","NA","zinc finger protein 343 [Source:HGNC Symbol;Acc:HGNC:16017];small nuclear ribonucleoprotein polypeptides B and B1 [Source:HGNC Symbol;Acc:HGNC:11153]",{"v":5.18761936851883,"d":"5.19"},{"v":10.31243563013,"d":"10.31"},{"v":0.503045018129576,"d":"0.50"},{"v":-0.991240580490578,"d":"-0.99"},{"v":0.0581296113312309,"d":"0.06"},{"v":0.542643801048867,"d":"0.54"},"down","no"]
["ENSG00000072121","ZFYVE26","ENST00000347230;ENST00000555452;ENST00000553399;ENST00000554783;ENST00000557306;ENST00000394455;ENST00000554523;ENST00000557366;ENST00000557204;ENST00000557407","GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0005765(lysosomal membrane);GO:0051301(cell division);GO:0005856(cytoskeleton);GO:0006281(DNA repair);GO:0006974(cellular response to DNA damage stimulus);GO:0007049(cell cycle);GO:0032266(phosphatidylinositol-3-phosphate binding);GO:0000724(double-strand break repair via homologous recombination);GO:0005813(centrosome);GO:0005815(microtubule organizing center);GO:0030496(midbody);GO:0008289(lipid binding);GO:0000910(cytokinesis);GO:0005515(protein binding);GO:0005515(protein binding)","NA","NA","NA","zinc finger FYVE-type containing 26 [Source:HGNC Symbol;Acc:HGNC:20761]",{"v":2.09010543104546,"d":"2.09"},{"v":0.720862582770916,"d":"0.72"},{"v":2.89945057629615,"d":"2.90"},{"v":1.53577954646476,"d":"1.54"},{"v":0.0581426711279077,"d":"0.06"},{"v":0.542643801048867,"d":"0.54"},"up","no"]
["MSTRG.6420","RPL26;AC135178.2;KRBA2","ENST00000584343;ENST00000584164;ENST00000582556;ENST00000293842;ENST00000582471;ENST00000583515;ENST00000584906;ENST00000396267;ENST00000578069;ENST00000578115;ENST00000584441;ENST00000585176;ENST00000582485;ENST00000578812","GO:0003723(RNA binding);GO:0016020(membrane);GO:0006412(translation);GO:0030529(intracellular ribonucleoprotein complex);GO:0005622(intracellular);GO:0003735(structural constituent of ribosome);GO:0005840(ribosome);GO:0015934(large ribosomal subunit);GO:0006364(rRNA processing);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0042273(ribosomal large subunit biogenesis);GO:0005515(protein binding);GO:0002181(cytoplasmic translation);GO:0006413(translational initiation);GO:0005737(cytoplasm);GO:0000184(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay);GO:0019083(viral transcription);GO:0048027(mRNA 5'-UTR binding);GO:0006614(SRP-dependent cotranslational protein targeting to membrane);GO:0071480(cellular response to gamma radiation);GO:0005654(nucleoplasm);GO:0006977(DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest);GO:0034644(cellular response to UV);GO:0022625(cytosolic large ribosomal subunit);GO:0005730(nucleolus);GO:0045727(positive regulation of translation);GO:1902164(positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator);GO:1902167(positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator);GO:1904803(regulation of translation involved in cellular response to UV);GO:0022626(cytosolic ribosome);GO:1990904(ribonucleoprotein complex);GO:0071479(cellular response to ionizing radiation);GO:0003676(nucleic acid binding);GO:0015074(DNA integration);GO:0006355(regulation of transcription, DNA-templated);GO:0071479(cellular response to ionizing radiation)","03010(Ribosome);03010(Ribosome)","K02898","NA","ribosomal protein L26 [Source:HGNC Symbol;Acc:HGNC:10327];KRAB-A domain containing 2 [Source:HGNC Symbol;Acc:HGNC:26989]",{"v":61.4287012510763,"d":"61.43"},{"v":121.793647972619,"d":"121.79"},{"v":0.504367036160099,"d":"0.50"},{"v":-0.987454106141135,"d":"-0.99"},{"v":0.0581754527086747,"d":"0.06"},{"v":0.542643801048867,"d":"0.54"},"down","no"]
["ENSG00000100142","POLR2F","ENST00000442738;ENST00000427034;ENST00000492213;ENST00000608713;ENST00000483713;ENST00000606538;ENST00000484894;ENST00000470701;ENST00000488684;ENST00000443002","GO:0005634(nucleus);GO:0003677(DNA binding);GO:0001650(fibrillar center);GO:0005665(DNA-directed RNA polymerase II, core complex);GO:0006351(transcription, DNA-templated);GO:0003899(DNA-directed 5'-3' RNA polymerase activity);GO:0005666(DNA-directed RNA polymerase III complex);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0006366(transcription from RNA polymerase II promoter);GO:0045815(positive regulation of gene expression, epigenetic);GO:0006368(transcription elongation from RNA polymerase II promoter);GO:0006370(7-methylguanosine mRNA capping);GO:0050434(positive regulation of viral transcription);GO:0006367(transcription initiation from RNA polymerase II promoter);GO:0042795(snRNA transcription from RNA polymerase II promoter);GO:0001056(RNA polymerase III activity);GO:0006383(transcription from RNA polymerase III promoter);GO:0032481(positive regulation of type I interferon production);GO:0000398(mRNA splicing, via spliceosome);GO:0001054(RNA polymerase I activity);GO:0006361(transcription initiation from RNA polymerase I promoter);GO:0006362(transcription elongation from RNA polymerase I promoter);GO:0006363(termination of RNA polymerase I transcription);GO:0005736(DNA-directed RNA polymerase I complex);GO:0060964(regulation of gene silencing by miRNA);GO:0006283(transcription-coupled nucleotide-excision repair);GO:0008543(fibroblast growth factor receptor signaling pathway);GO:0016070(RNA metabolic process);GO:0035019(somatic stem cell population maintenance);GO:0001055(RNA polymerase II activity);GO:0001055(RNA polymerase II activity)","00230(Purine metabolism);00240(Pyrimidine metabolism);03020(RNA polymerase);04623(Cytosolic DNA-sensing pathway);05016(Huntington's disease);05169(Epstein-Barr virus infection);05169(Epstein-Barr virus infection)","K03014","NA","RNA polymerase II subunit F [Source:HGNC Symbol;Acc:HGNC:9193]",{"v":0.66586544973019,"d":"0.67"},{"v":1.33543207384266,"d":"1.34"},{"v":0.498614240868265,"d":"0.50"},{"v":-1.00400400681,"d":"-1.00"},{"v":0.0582253817560999,"d":"0.06"},{"v":0.542673642322302,"d":"0.54"},"down","no"]
["MSTRG.10639","SETD5","ENST00000402198;ENST00000466242;ENST00000493918;ENST00000488236;ENST00000466826;ENST00000478475;ENST00000442373;ENST00000302463;ENST00000466172;ENST00000431285;ENST00000459941;ENST00000486465;MSTRG.10639.14;ENST00000492939;ENST00000413704;ENST00000490791;ENST00000415650;ENST00000450326;ENST00000399686;ENST00000476740;ENST00000478961;ENST00000463180;ENST00000443339;ENST00000407969;ENST00000406341;ENST00000421188","GO:0005634(nucleus);GO:0016569(covalent chromatin modification);GO:0016593(Cdc73/Paf1 complex);GO:1902275(regulation of chromatin organization);GO:0035065(regulation of histone acetylation);GO:0035065(regulation of histone acetylation)","NA","NA","NA","SET domain containing 5 [Source:HGNC Symbol;Acc:HGNC:25566]",{"v":4.71570959856565,"d":"4.72"},{"v":1.63176075248253,"d":"1.63"},{"v":2.8899516006812,"d":"2.89"},{"v":1.53104533146578,"d":"1.53"},{"v":0.0584336965766638,"d":"0.06"},{"v":0.543821203102492,"d":"0.54"},"up","no"]
["MSTRG.8185","RPS19","ENST00000221975;ENST00000598742;ENST00000593863;ENST00000601492;ENST00000598399;ENST00000598261;ENST00000600467;ENST00000598466","GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0006412(translation);GO:0030529(intracellular ribonucleoprotein complex);GO:0005622(intracellular);GO:0003735(structural constituent of ribosome);GO:0005840(ribosome);GO:0005829(cytosol);GO:0042803(protein homodimerization activity);GO:0005515(protein binding);GO:0000028(ribosomal small subunit assembly);GO:0022627(cytosolic small ribosomal subunit);GO:0005730(nucleolus);GO:0005925(focal adhesion);GO:0006364(rRNA processing);GO:0042274(ribosomal small subunit biogenesis);GO:0005654(nucleoplasm);GO:0070062(extracellular exosome);GO:0019901(protein kinase binding);GO:0050829(defense response to Gram-negative bacterium);GO:0031012(extracellular matrix);GO:0007219(Notch signaling pathway);GO:0061844(antimicrobial humoral immune response mediated by antimicrobial peptide);GO:0006413(translational initiation);GO:0030490(maturation of SSU-rRNA);GO:0000184(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay);GO:0031640(killing of cells of other organism);GO:0019083(viral transcription);GO:0051262(protein tetramerization);GO:0017134(fibroblast growth factor binding);GO:0006614(SRP-dependent cotranslational protein targeting to membrane);GO:0002548(monocyte chemotaxis);GO:0000462(maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA));GO:0007000(nucleolus organization);GO:0009991(response to extracellular stimulus);GO:0030218(erythrocyte differentiation);GO:0051272(positive regulation of cellular component movement);GO:0060265(positive regulation of respiratory burst involved in inflammatory response);GO:0060266(negative regulation of respiratory burst involved in inflammatory response);GO:0060266(negative regulation of respiratory burst involved in inflammatory response)","03010(Ribosome);03010(Ribosome)","K02966","NA","ribosomal protein S19 [Source:HGNC Symbol;Acc:HGNC:10402]",{"v":59.2922004144547,"d":"59.29"},{"v":117.444327013929,"d":"117.44"},{"v":0.504853677669953,"d":"0.50"},{"v":-0.986062784425775,"d":"-0.99"},{"v":0.05844216494204,"d":"0.06"},{"v":0.543821203102492,"d":"0.54"},"down","no"]
["MSTRG.8874","VAMP5","ENST00000306384;ENST00000462451","GO:0048471(perinuclear region of cytoplasm);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016192(vesicle-mediated transport);GO:0005794(Golgi apparatus);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0007275(multicellular organism development);GO:0030154(cell differentiation);GO:0006906(vesicle fusion);GO:0070062(extracellular exosome);GO:0012505(endomembrane system);GO:0007517(muscle organ development);GO:0000149(SNARE binding);GO:0005484(SNAP receptor activity);GO:0031201(SNARE complex);GO:0006887(exocytosis);GO:0009986(cell surface);GO:0005770(late endosome);GO:0014704(intercalated disc);GO:0007519(skeletal muscle tissue development);GO:0043001(Golgi to plasma membrane protein transport);GO:0005887(integral component of plasma membrane);GO:0030659(cytoplasmic vesicle membrane);GO:0031301(integral component of organelle membrane);GO:0031301(integral component of organelle membrane)","04130(SNARE interactions in vesicular transport);04130(SNARE interactions in vesicular transport)","K08514","NA","vesicle associated membrane protein 5 [Source:HGNC Symbol;Acc:HGNC:12646]",{"v":13.4681083235653,"d":"13.47"},{"v":26.8141598168498,"d":"26.81"},{"v":0.502275977153759,"d":"0.50"},{"v":-0.993447819419585,"d":"-0.99"},{"v":0.0585741194161516,"d":"0.06"},{"v":0.544612689175155,"d":"0.54"},"down","no"]
["MSTRG.9841","RPL12P4","ENST00000432629","NA","NA","NA","NA","ribosomal protein L12 pseudogene 4 [Source:HGNC Symbol;Acc:HGNC:16587]",{"v":3.964443,"d":"3.96"},{"v":8.045675,"d":"8.05"},{"v":0.492742125427637,"d":"0.49"},{"v":-1.02109527932083,"d":"-1.02"},{"v":0.0586918380466635,"d":"0.06"},{"v":0.544637848511815,"d":"0.54"},"down","no"]
["MSTRG.10576","PRR34-AS1;MIRLET7BHG","ENST00000451166;ENST00000381051;ENST00000416202;ENST00000360737;ENST00000435439","NA","NA","NA","NA","PRR34 antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:50499];MIRLET7B host gene [Source:HGNC Symbol;Acc:HGNC:37189]",{"v":0.168555568473925,"d":"0.17"},{"v":0.351419885950657,"d":"0.35"},{"v":0.479641520621266,"d":"0.48"},{"v":-1.0599715424705,"d":"-1.06"},{"v":0.058727452193086,"d":"0.06"},{"v":0.544637848511815,"d":"0.54"},"down","no"]
["MSTRG.7558","NFATC1","ENST00000329101;ENST00000318065;ENST00000592223;ENST00000253506;ENST00000590224;ENST00000586434;ENST00000591065;ENST00000542384;ENST00000586695;ENST00000587635;ENST00000591814;ENST00000545796;ENST00000397790;ENST00000590313;ENST00000591089;ENST00000427363","GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0005737(cytoplasm);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0005515(protein binding);GO:0016604(nuclear body);GO:0045893(positive regulation of transcription, DNA-templated);GO:0038095(Fc-epsilon receptor signaling pathway);GO:0005829(cytosol);GO:0000790(nuclear chromatin);GO:0006366(transcription from RNA polymerase II promoter);GO:0001085(RNA polymerase II transcription factor binding);GO:0000980(RNA polymerase II distal enhancer sequence-specific DNA binding);GO:0003705(transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding);GO:0035556(intracellular signal transduction);GO:0007223(Wnt signaling pathway, calcium modulating pathway);GO:0005528(FK506 binding);GO:0001205(transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding);GO:0048273(mitogen-activated protein kinase p38 binding);GO:0030178(negative regulation of Wnt signaling pathway);GO:0033173(calcineurin-NFAT signaling cascade);GO:0000977(RNA polymerase II regulatory region sequence-specific DNA binding);GO:0001225(RNA polymerase II transcription coactivator binding);GO:0001225(RNA polymerase II transcription coactivator binding)","04010(MAPK signaling pathway);04310(Wnt signaling pathway);04024(cAMP signaling pathway);04022(cGMP - PKG signaling pathway);04218(Cellular senescence);04650(Natural killer cell mediated cytotoxicity);04660(T cell receptor signaling pathway);04658(Th1 and Th2 cell differentiation);04659(Th17 cell differentiation);04662(B cell receptor signaling pathway);04921(Oxytocin signaling pathway);04380(Osteoclast differentiation);05321(Inflammatiory bowel disease (IBD));04933(AGE-RAGE signaling pathway in diabetic complications);05166(HTLV-I infection);05161(Hepatitis B);05167(Kaposi's sarcoma-associated herpesvirus infection);05167(Kaposi's sarcoma-associated herpesvirus infection)","K04446","NA","nuclear factor of activated T-cells 1 [Source:HGNC Symbol;Acc:HGNC:7775]",{"v":3.92112647518747,"d":"3.92"},{"v":1.35656279124393,"d":"1.36"},{"v":2.8904865299983,"d":"2.89"},{"v":1.53131234924462,"d":"1.53"},{"v":0.0587863732467353,"d":"0.06"},{"v":0.544637848511815,"d":"0.54"},"up","no"]
["MSTRG.6347","CAMTA2","ENST00000574951;ENST00000571831;ENST00000574442;ENST00000576872;ENST00000361571;ENST00000572326;ENST00000575192;ENST00000575580;ENST00000348066;ENST00000572543;ENST00000574606;MSTRG.6347.2;ENST00000572192","GO:0005634(nucleus);GO:0003677(DNA binding);GO:0006366(transcription from RNA polymerase II promoter);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0005515(protein binding);GO:0001077(transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0043565(sequence-specific DNA binding);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0003682(chromatin binding);GO:0008134(transcription factor binding);GO:0042826(histone deacetylase binding);GO:0014898(cardiac muscle hypertrophy in response to stress);GO:0014898(cardiac muscle hypertrophy in response to stress)","NA","NA","NA","calmodulin binding transcription activator 2 [Source:HGNC Symbol;Acc:HGNC:18807]",{"v":6.45409698100317,"d":"6.45"},{"v":2.23692936843859,"d":"2.24"},{"v":2.88524844461595,"d":"2.89"},{"v":1.52869555262569,"d":"1.53"},{"v":0.0588083971828956,"d":"0.06"},{"v":0.544637848511815,"d":"0.54"},"up","no"]
["ENSG00000214784","AC010468.1","ENST00000461022","NA","NA","NA","NA",null,{"v":1.110798,"d":"1.11"},{"v":2.311783,"d":"2.31"},{"v":0.480494060212399,"d":"0.48"},{"v":-1.05740949813409,"d":"-1.06"},{"v":0.0588113202474654,"d":"0.06"},{"v":0.544637848511815,"d":"0.54"},"down","no"]
["ENSG00000105497","ZNF175","ENST00000262259;ENST00000545217;ENST00000600460;ENST00000596504","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0006355(regulation of transcription, DNA-templated);GO:0006366(transcription from RNA polymerase II promoter);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0005622(intracellular);GO:0045111(intermediate filament cytoskeleton);GO:0005515(protein binding);GO:0051607(defense response to virus);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0001228(transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0000977(RNA polymerase II regulatory region sequence-specific DNA binding);GO:0001227(transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding);GO:0001227(transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding)","NA","NA","NA","zinc finger protein 175 [Source:HGNC Symbol;Acc:HGNC:12964]",{"v":0.94862337155219,"d":"0.95"},{"v":0.321943962547323,"d":"0.32"},{"v":2.94654810124837,"d":"2.95"},{"v":1.55902581781553,"d":"1.56"},{"v":0.0589223464492292,"d":"0.06"},{"v":0.545231242481991,"d":"0.55"},"up","no"]
["MSTRG.1832","GHITM","ENST00000372134","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005739(mitochondrion);GO:0005743(mitochondrial inner membrane);GO:0005515(protein binding);GO:0006915(apoptotic process);GO:0003674(molecular_function);GO:0008150(biological_process);GO:0070062(extracellular exosome)","NA","NA","NA","growth hormone inducible transmembrane protein [Source:HGNC Symbol;Acc:HGNC:17281]",{"v":30.332609,"d":"30.33"},{"v":59.990295,"d":"59.99"},{"v":0.505625268220468,"d":"0.51"},{"v":-0.98385953203402,"d":"-0.98"},{"v":0.0590042850144342,"d":"0.06"},{"v":0.545311568117893,"d":"0.55"},"down","no"]
["MSTRG.7032","NME2;NME1;NME1-NME2","ENST00000393190;ENST00000393196;ENST00000512737;ENST00000393183;ENST00000480143;ENST00000336097;ENST00000503064;ENST00000512768;ENST00000570801;ENST00000487481;ENST00000376392;ENST00000393193;ENST00000573262;ENST00000555572;ENST00000511355;ENST00000485076;ENST00000514264;ENST00000513177","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0042995(cell projection);GO:0005515(protein binding);GO:0007229(integrin-mediated signaling pathway);GO:0004550(nucleoside diphosphate kinase activity);GO:0006165(nucleoside diphosphate phosphorylation);GO:0006183(GTP biosynthetic process);GO:0006228(UTP biosynthetic process);GO:0006241(CTP biosynthetic process);GO:0009117(nucleotide metabolic process);GO:0005576(extracellular region);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0005829(cytosol);GO:0030027(lamellipodium);GO:0070062(extracellular exosome);GO:0071944(cell periphery);GO:0043312(neutrophil degranulation);GO:0001726(ruffle);GO:0034774(secretory granule lumen);GO:1904813(ficolin-1-rich granule lumen);GO:0015949(nucleobase-containing small molecule interconversion);GO:0009142(nucleoside triphosphate biosynthetic process);GO:0050679(positive regulation of epithelial cell proliferation);GO:0043066(negative regulation of apoptotic process);GO:0007155(cell adhesion);GO:0004673(protein histidine kinase activity);GO:0018106(peptidyl-histidine phosphorylation);GO:0045618(positive regulation of keratinocyte differentiation);GO:0045682(regulation of epidermis development);GO:0004674(protein serine/threonine kinase activity);GO:0005504(fatty acid binding);GO:0008144(drug binding);GO:0019215(intermediate filament binding);GO:0019899(enzyme binding);GO:0002762(negative regulation of myeloid leukocyte differentiation);GO:0010976(positive regulation of neuron projection development);GO:0030819(positive regulation of cAMP biosynthetic process);GO:0034599(cellular response to oxidative stress);GO:0046777(protein autophosphorylation);GO:0051259(protein oligomerization);GO:0060416(response to growth hormone);GO:0071333(cellular response to glucose stimulus);GO:0071398(cellular response to fatty acid);GO:0005882(intermediate filament);GO:0031966(mitochondrial membrane);GO:0048471(perinuclear region of cytoplasm);GO:0003723(RNA binding);GO:0016020(membrane);GO:0005525(GTP binding);GO:0006259(DNA metabolic process);GO:0000287(magnesium ion binding);GO:0007399(nervous system development);GO:0030154(cell differentiation);GO:0042802(identical protein binding);GO:0006897(endocytosis);GO:0008285(negative regulation of cell proliferation);GO:0032587(ruffle membrane);GO:0042981(regulation of apoptotic process);GO:0043024(ribosomal small subunit binding);GO:0043388(positive regulation of DNA binding);GO:0004536(deoxyribonuclease activity);GO:0000977(RNA polymerase II regulatory region sequence-specific DNA binding);GO:0003697(single-stranded DNA binding);GO:0019901(protein kinase binding);GO:0043015(gamma-tubulin binding);GO:0007595(lactation);GO:0010629(negative regulation of gene expression);GO:0014075(response to amine);GO:0021766(hippocampus development);GO:0030879(mammary gland development);GO:0033574(response to testosterone);GO:0035690(cellular response to drug);GO:0042493(response to drug);GO:0051591(response to cAMP);GO:0005739(mitochondrion);GO:0005741(mitochondrial outer membrane);GO:0005813(centrosome);GO:0043209(myelin sheath);GO:0048471(perinuclear region of cytoplasm)","00230(Purine metabolism);00240(Pyrimidine metabolism);00983(Drug metabolism - other enzymes);00983(Drug metabolism - other enzymes)","K00940","EC:2.7.4.6","NME/NM23 nucleoside diphosphate kinase 2 [Source:HGNC Symbol;Acc:HGNC:7850];NME/NM23 nucleoside diphosphate kinase 1 [Source:HGNC Symbol;Acc:HGNC:7849];NME1-NME2 readthrough [Source:HGNC Symbol;Acc:HGNC:33531]",{"v":7.90180333492587,"d":"7.90"},{"v":15.6513265545305,"d":"15.65"},{"v":0.504864767046764,"d":"0.50"},{"v":-0.986031095217728,"d":"-0.99"},{"v":0.059024941111185,"d":"0.06"},{"v":0.545311568117893,"d":"0.55"},"down","no"]
["ENSG00000103257","SLC7A5","ENST00000261622;ENST00000563489","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0043231(intracellular membrane-bounded organelle);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0015171(amino acid transmembrane transporter activity);GO:0003333(amino acid transmembrane transport);GO:0006810(transport);GO:0005737(cytoplasm);GO:0007275(multicellular organism development);GO:0007399(nervous system development);GO:0030154(cell differentiation);GO:0006865(amino acid transport);GO:0050900(leukocyte migration);GO:0005887(integral component of plasma membrane);GO:0070062(extracellular exosome);GO:0015297(antiporter activity);GO:0016324(apical plasma membrane);GO:0042605(peptide antigen binding);GO:0006520(cellular amino acid metabolic process);GO:0015179(L-amino acid transmembrane transporter activity);GO:0015804(neutral amino acid transport);GO:1902475(L-alpha-amino acid transmembrane transport);GO:0015175(neutral amino acid transmembrane transporter activity);GO:0015807(L-amino acid transport);GO:0015807(L-amino acid transport)","04150(mTOR signaling pathway);05230(Central carbon metabolism in cancer);05230(Central carbon metabolism in cancer)","K13780","NA","solute carrier family 7 member 5 [Source:HGNC Symbol;Acc:HGNC:11063]",{"v":2.6608458,"d":"2.66"},{"v":0.918438917808219,"d":"0.92"},{"v":2.89713964468089,"d":"2.90"},{"v":1.5346292254551,"d":"1.53"},{"v":0.0590954107426243,"d":"0.06"},{"v":0.545380691063276,"d":"0.55"},"up","no"]
["MSTRG.3073","C12orf57","ENST00000229281;ENST00000537087;ENST00000544681;ENST00000540506;ENST00000542222;ENST00000538392;ENST00000545581","GO:0005737(cytoplasm);GO:0003674(molecular_function);GO:0050890(cognition);GO:0009791(post-embryonic development);GO:0014819(regulation of skeletal muscle contraction);GO:0021540(corpus callosum morphogenesis);GO:0021678(third ventricle development);GO:0036343(psychomotor behavior);GO:0048593(camera-type eye morphogenesis);GO:0048593(camera-type eye morphogenesis)","NA","NA","NA","chromosome 12 open reading frame 57 [Source:HGNC Symbol;Acc:HGNC:29521]",{"v":10.8902277487548,"d":"10.89"},{"v":21.5714739640288,"d":"21.57"},{"v":0.504843932635973,"d":"0.50"},{"v":-0.98609063258953,"d":"-0.99"},{"v":0.059126348923505,"d":"0.06"},{"v":0.545380691063276,"d":"0.55"},"down","no"]
["MSTRG.1177","XCL2","ENST00000367819","GO:0005576(extracellular region);GO:0005515(protein binding);GO:0006955(immune response);GO:0005125(cytokine activity);GO:0005615(extracellular space);GO:0008009(chemokine activity);GO:0006935(chemotaxis);GO:0007186(G-protein coupled receptor signaling pathway);GO:0048020(CCR chemokine receptor binding);GO:0002548(monocyte chemotaxis);GO:0006954(inflammatory response);GO:0030593(neutrophil chemotaxis);GO:0043547(positive regulation of GTPase activity);GO:0048247(lymphocyte chemotaxis);GO:0070098(chemokine-mediated signaling pathway);GO:0070374(positive regulation of ERK1 and ERK2 cascade);GO:0071346(cellular response to interferon-gamma);GO:0071347(cellular response to interleukin-1);GO:0071356(cellular response to tumor necrosis factor);GO:0007165(signal transduction);GO:0008015(blood circulation)","04060(Cytokine-cytokine receptor interaction);04062(Chemokine signaling pathway)","K05507","NA","X-C motif chemokine ligand 2 [Source:HGNC Symbol;Acc:HGNC:10646]",{"v":3.007432,"d":"3.01"},{"v":6.11519,"d":"6.12"},{"v":0.49179698423107,"d":"0.49"},{"v":-1.02386520673706,"d":"-1.02"},{"v":0.0593375913160059,"d":"0.06"},{"v":0.546496275359962,"d":"0.55"},"down","no"]
["MSTRG.9347","NDUFB3","ENST00000237889;ENST00000433898;ENST00000450023;ENST00000454214","GO:0022900(electron transport chain);GO:0005739(mitochondrion);GO:0005747(mitochondrial respiratory chain complex I);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0055114(oxidation-reduction process);GO:0005743(mitochondrial inner membrane);GO:0070469(respiratory chain);GO:0070062(extracellular exosome);GO:0032981(mitochondrial respiratory chain complex I assembly);GO:0008137(NADH dehydrogenase (ubiquinone) activity);GO:0006120(mitochondrial electron transport, NADH to ubiquinone);GO:0006120(mitochondrial electron transport, NADH to ubiquinone)","00190(Oxidative phosphorylation);04723(Retrograde endocannabinoid signaling);05010(Alzheimer's disease);05012(Parkinson's disease);05016(Huntington's disease);04932(Non-alcoholic fatty liver disease (NAFLD));04932(Non-alcoholic fatty liver disease (NAFLD))","K03959","NA","NADH:ubiquinone oxidoreductase subunit B3 [Source:HGNC Symbol;Acc:HGNC:7698]",{"v":13.7614197443336,"d":"13.76"},{"v":27.2728857171351,"d":"27.27"},{"v":0.504582459189037,"d":"0.50"},{"v":-0.986838040140413,"d":"-0.99"},{"v":0.0593414107662889,"d":"0.06"},{"v":0.546496275359962,"d":"0.55"},"down","no"]
["MSTRG.385","ZNF362","ENST00000373428;MSTRG.385.1;ENST00000490959;ENST00000539719;ENST00000477934","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0003677(DNA binding)","NA","NA","NA","zinc finger protein 362 [Source:HGNC Symbol;Acc:HGNC:18079]",{"v":2.95564572320624,"d":"2.96"},{"v":1.00978575262684,"d":"1.01"},{"v":2.92700279788804,"d":"2.93"},{"v":1.54942412480279,"d":"1.55"},{"v":0.0593923883937571,"d":"0.06"},{"v":0.546532334720048,"d":"0.55"},"up","no"]
["MSTRG.1082","NAXE","ENST00000368235;ENST00000488840;ENST00000368233;ENST00000467374;ENST00000368234","GO:0043231(intracellular membrane-bounded organelle);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0005615(extracellular space);GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0016853(isomerase activity);GO:0005739(mitochondrion);GO:0005576(extracellular region);GO:0046496(nicotinamide nucleotide metabolic process);GO:0005515(protein binding);GO:0008150(biological_process);GO:0070062(extracellular exosome);GO:0005759(mitochondrial matrix);GO:0034356(NAD biosynthesis via nicotinamide riboside salvage pathway);GO:0006734(NADH metabolic process);GO:0042803(protein homodimerization activity);GO:0052856(NADHX epimerase activity);GO:0052857(NADPHX epimerase activity);GO:0006739(NADP metabolic process);GO:0051289(protein homotetramerization);GO:0005634(nucleus);GO:0005929(cilium);GO:0044297(cell body);GO:0044297(cell body)","NA","NA","NA","NAD(P)HX epimerase [Source:HGNC Symbol;Acc:HGNC:18453]",{"v":5.42500607863425,"d":"5.43"},{"v":10.7801560863942,"d":"10.78"},{"v":0.503240030585571,"d":"0.50"},{"v":-0.990681407904128,"d":"-0.99"},{"v":0.0594871358227019,"d":"0.06"},{"v":0.546970790426791,"d":"0.55"},"down","no"]
["ENSG00000220804","LINC01881","ENST00000456398;ENST00000433444;ENST00000614114;ENST00000431796;ENST00000622435","NA","NA","NA","NA","long intergenic non-protein coding RNA 1881 [Source:HGNC Symbol;Acc:HGNC:52700]",{"v":1.5954025592957,"d":"1.60"},{"v":0.536035221646815,"d":"0.54"},{"v":2.97630173329708,"d":"2.98"},{"v":1.57352079226083,"d":"1.57"},{"v":0.0596119041707434,"d":"0.06"},{"v":0.547396809022787,"d":"0.55"},"up","no"]
["MSTRG.6369","TXNDC17","ENST00000250101;ENST00000570330;ENST00000571029;ENST00000574429;ENST00000576020;ENST00000574734;ENST00000571957","GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0055114(oxidation-reduction process);GO:0005515(protein binding);GO:0098869(cellular oxidant detoxification);GO:0004601(peroxidase activity);GO:0070062(extracellular exosome);GO:0033209(tumor necrosis factor-mediated signaling pathway);GO:0047134(protein-disulfide reductase activity);GO:0047134(protein-disulfide reductase activity)","NA","NA","NA","thioredoxin domain containing 17 [Source:HGNC Symbol;Acc:HGNC:28218]",{"v":0.983060698731501,"d":"0.98"},{"v":1.9671630269556,"d":"1.97"},{"v":0.499735245762978,"d":"0.50"},{"v":-1.00076412157189,"d":"-1.00"},{"v":0.0596277416183437,"d":"0.06"},{"v":0.547396809022787,"d":"0.55"},"down","no"]
["ENSG00000102781","KATNAL1","ENST00000380615;ENST00000441394;ENST00000380617","GO:0005737(cytoplasm);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0016787(hydrolase activity);GO:0051301(cell division);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0007049(cell cycle);GO:0008017(microtubule binding);GO:0005874(microtubule);GO:0008568(microtubule-severing ATPase activity);GO:0051013(microtubule severing);GO:0000922(spindle pole);GO:0005813(centrosome);GO:0005815(microtubule organizing center);GO:0005819(spindle);GO:0030496(midbody);GO:0005634(nucleus);GO:0042802(identical protein binding);GO:0016887(ATPase activity);GO:0016887(ATPase activity)","NA","NA","NA","katanin catalytic subunit A1 like 1 [Source:HGNC Symbol;Acc:HGNC:28361]",{"v":0.594886506107341,"d":"0.59"},{"v":0.199937009376928,"d":"0.20"},{"v":2.9753696324718,"d":"2.98"},{"v":1.57306890667556,"d":"1.57"},{"v":0.059830403448711,"d":"0.06"},{"v":0.548680461935771,"d":"0.55"},"up","no"]
["MSTRG.8290","RPL18;AC022154.1","ENST00000550973;ENST00000549920;ENST00000549273;ENST00000084795;ENST00000552588;ENST00000598735;ENST00000550645;ENST00000600303;ENST00000594850;ENST00000547892;ENST00000549370;ENST00000547897;ENST00000552347;ENST00000550671;ENST00000552705;ENST00000552851;ENST00000546623;ENST00000549533;ENST00000551749","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0006412(translation);GO:0005783(endoplasmic reticulum);GO:0005730(nucleolus);GO:0005829(cytosol);GO:0030529(intracellular ribonucleoprotein complex);GO:0005622(intracellular);GO:0003735(structural constituent of ribosome);GO:0005840(ribosome);GO:0005925(focal adhesion);GO:0006413(translational initiation);GO:0003723(RNA binding);GO:0006364(rRNA processing);GO:0000184(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay);GO:0019083(viral transcription);GO:0006614(SRP-dependent cotranslational protein targeting to membrane);GO:0022625(cytosolic large ribosomal subunit);GO:0022625(cytosolic large ribosomal subunit)","03010(Ribosome);03010(Ribosome)","K02883","NA","ribosomal protein L18 [Source:HGNC Symbol;Acc:HGNC:10310]",{"v":42.1738548604475,"d":"42.17"},{"v":83.1246530384907,"d":"83.12"},{"v":0.507356762631165,"d":"0.51"},{"v":-0.978927517928338,"d":"-0.98"},{"v":0.0599142855602034,"d":"0.06"},{"v":0.548680461935771,"d":"0.55"},"down","no"]
["MSTRG.11926","SPCS3","ENST00000503362;ENST00000507678;ENST00000507001;ENST00000513139","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016787(hydrolase activity);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0008233(peptidase activity);GO:0006508(proteolysis);GO:0006465(signal peptide processing);GO:0005787(signal peptidase complex);GO:0043231(intracellular membrane-bounded organelle);GO:0031090(organelle membrane);GO:0045047(protein targeting to ER);GO:0045047(protein targeting to ER)","03060(Protein export);03060(Protein export)","K12948","EC:3.4.-.-","signal peptidase complex subunit 3 [Source:HGNC Symbol;Acc:HGNC:26212]",{"v":2.91570164880691,"d":"2.92"},{"v":1.01111651690821,"d":"1.01"},{"v":2.88364555424585,"d":"2.88"},{"v":1.52789384538406,"d":"1.53"},{"v":0.0599271303115559,"d":"0.06"},{"v":0.548680461935771,"d":"0.55"},"up","no"]
["MSTRG.8320","SCAF1","ENST00000360565;ENST00000601038;ENST00000598359;ENST00000595242","GO:0003723(RNA binding);GO:0006397(mRNA processing);GO:0008380(RNA splicing);GO:0005634(nucleus);GO:0019904(protein domain specific binding);GO:0006366(transcription from RNA polymerase II promoter);GO:0006366(transcription from RNA polymerase II promoter)","NA","NA","NA","SR-related CTD associated factor 1 [Source:HGNC Symbol;Acc:HGNC:30403]",{"v":6.22254542128408,"d":"6.22"},{"v":2.16585517941953,"d":"2.17"},{"v":2.87302008020305,"d":"2.87"},{"v":1.5225680762356,"d":"1.52"},{"v":0.0599565578400494,"d":"0.06"},{"v":0.548680461935771,"d":"0.55"},"up","no"]
["MSTRG.2758","GAB2","ENST00000361507;ENST00000530915;ENST00000526030;ENST00000528329;ENST00000534823;ENST00000528886","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0048015(phosphatidylinositol-mediated signaling);GO:0038095(Fc-epsilon receptor signaling pathway);GO:0005829(cytosol);GO:0005547(phosphatidylinositol-3,4,5-trisphosphate binding);GO:0043325(phosphatidylinositol-3,4-bisphosphate binding);GO:0008284(positive regulation of cell proliferation);GO:0007411(axon guidance);GO:0030316(osteoclast differentiation);GO:0043306(positive regulation of mast cell degranulation);GO:0005068(transmembrane receptor protein tyrosine kinase adaptor activity);GO:0007169(transmembrane receptor protein tyrosine kinase signaling pathway);GO:0007169(transmembrane receptor protein tyrosine kinase signaling pathway)","04014(Ras signaling pathway);04072(Phospholipase D signaling pathway);04071(Sphingolipid signaling pathway);04664(Fc epsilon RI signaling pathway);04666(Fc gamma R-mediated phagocytosis);04380(Osteoclast differentiation);05220(Chronic myeloid leukemia);05220(Chronic myeloid leukemia)","K08091","NA","GRB2 associated binding protein 2 [Source:HGNC Symbol;Acc:HGNC:14458]",{"v":13.0369517326835,"d":"13.04"},{"v":4.55037234219465,"d":"4.55"},{"v":2.86502966181351,"d":"2.87"},{"v":1.51855007536254,"d":"1.52"},{"v":0.0601599261422383,"d":"0.06"},{"v":0.549279533984044,"d":"0.55"},"up","no"]
["MSTRG.12902","HLA-DRA","ENST00000374982;ENST00000395388","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005794(Golgi apparatus);GO:0005765(lysosomal membrane);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005886(plasma membrane);GO:0006955(immune response);GO:0002376(immune system process);GO:0005764(lysosome);GO:0005887(integral component of plasma membrane);GO:0002504(antigen processing and presentation of peptide or polysaccharide antigen via MHC class II);GO:0019882(antigen processing and presentation);GO:0042613(MHC class II protein complex);GO:0005768(endosome);GO:0031902(late endosome membrane);GO:0070062(extracellular exosome);GO:0050852(T cell receptor signaling pathway);GO:0010008(endosome membrane);GO:0016032(viral process);GO:0019886(antigen processing and presentation of exogenous peptide antigen via MHC class II);GO:0032588(trans-Golgi network membrane);GO:0009986(cell surface);GO:0000139(Golgi membrane);GO:0030666(endocytic vesicle membrane);GO:0060333(interferon-gamma-mediated signaling pathway);GO:0050890(cognition);GO:0012507(ER to Golgi transport vesicle membrane);GO:0005515(protein binding);GO:0031295(T cell costimulation);GO:0042605(peptide antigen binding);GO:0071556(integral component of lumenal side of endoplasmic reticulum membrane);GO:0030669(clathrin-coated endocytic vesicle membrane);GO:0030658(transport vesicle membrane);GO:0023026(MHC class II protein complex binding);GO:0032395(MHC class II receptor activity);GO:0002503(peptide antigen assembly with MHC class II protein complex);GO:0002506(polysaccharide assembly with MHC class II protein complex);GO:0002506(polysaccharide assembly with MHC class II protein complex)","04514(Cell adhesion molecules (CAMs));04145(Phagosome);04640(Hematopoietic cell lineage);04612(Antigen processing and presentation);04658(Th1 and Th2 cell differentiation);04659(Th17 cell differentiation);04672(Intestinal immune network for IgA production);05310(Asthma);05322(Systemic lupus erythematosus);05323(Rheumatoid arthritis);05320(Autoimmune thyroid disease);05321(Inflammatiory bowel disease (IBD));05330(Allograft rejection);05332(Graft-versus-host disease);05416(Viral myocarditis);04940(Type I diabetes mellitus);05150(Staphylococcus aureus infection);05152(Tuberculosis);05166(HTLV-I infection);05164(Influenza A);05168(Herpes simplex infection);05169(Epstein-Barr virus infection);05145(Toxoplasmosis);05140(Leishmaniasis);05140(Leishmaniasis)","K06752","NA","major histocompatibility complex, class II, DR alpha [Source:HGNC Symbol;Acc:HGNC:4947]",{"v":347.055726563281,"d":"347.06"},{"v":683.144693682031,"d":"683.14"},{"v":0.508026673957915,"d":"0.51"},{"v":-0.977023847148724,"d":"-0.98"},{"v":0.0601889246209152,"d":"0.06"},{"v":0.549279533984044,"d":"0.55"},"down","no"]
["MSTRG.12454","RPL7P1","ENST00000468161","NA","NA","NA","NA","ribosomal protein L7 pseudogene 1 [Source:HGNC Symbol;Acc:HGNC:10367]",{"v":88.726761,"d":"88.73"},{"v":174.769623,"d":"174.77"},{"v":0.507678390998188,"d":"0.51"},{"v":-0.978013240892742,"d":"-0.98"},{"v":0.060199983945196,"d":"0.06"},{"v":0.549279533984044,"d":"0.55"},"down","no"]
["MSTRG.10594","PLXNB2","ENST00000449103;ENST00000359337;ENST00000479701;ENST00000463165;ENST00000432455;ENST00000614805;ENST00000425954;ENST00000434732;ENST00000492578;ENST00000411680;ENST00000479818;ENST00000496720","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0007165(signal transduction);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0007275(multicellular organism development);GO:0017154(semaphorin receptor activity);GO:0071526(semaphorin-plexin signaling pathway);GO:0005887(integral component of plasma membrane);GO:0070062(extracellular exosome);GO:0008360(regulation of cell shape);GO:0043087(regulation of GTPase activity);GO:0009986(cell surface);GO:0007405(neuroblast proliferation);GO:0007420(brain development);GO:0001843(neural tube closure);GO:0001932(regulation of protein phosphorylation);GO:0007156(homophilic cell adhesion via plasma membrane adhesion molecules);GO:0007162(negative regulation of cell adhesion);GO:0010976(positive regulation of neuron projection development);GO:0050772(positive regulation of axonogenesis);GO:2001222(regulation of neuron migration);GO:2001222(regulation of neuron migration)","04360(Axon guidance);04360(Axon guidance)","K06821","NA","plexin B2 [Source:HGNC Symbol;Acc:HGNC:9104]",{"v":13.6350425112305,"d":"13.64"},{"v":4.760526520463,"d":"4.76"},{"v":2.86418791127843,"d":"2.86"},{"v":1.51812614685368,"d":"1.52"},{"v":0.0602112155999042,"d":"0.06"},{"v":0.549279533984044,"d":"0.55"},"up","no"]
["MSTRG.15380","ITM2A","ENST00000373298;ENST00000462038;ENST00000434584;ENST00000482194;ENST00000469541;ENST00000461357","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005515(protein binding);GO:0005886(plasma membrane);GO:0007399(nervous system development);GO:0005794(Golgi apparatus);GO:0001540(amyloid-beta binding);GO:0002317(plasma cell differentiation);GO:0002377(immunoglobulin production);GO:0042985(negative regulation of amyloid precursor protein biosynthetic process);GO:0070062(extracellular exosome);GO:0070062(extracellular exosome)","NA","NA","NA","integral membrane protein 2A [Source:HGNC Symbol;Acc:HGNC:6173]",{"v":11.6019219419795,"d":"11.60"},{"v":22.8847041594344,"d":"22.88"},{"v":0.506972773654866,"d":"0.51"},{"v":-0.98001982372938,"d":"-0.98"},{"v":0.0603052186761893,"d":"0.06"},{"v":0.549705262548341,"d":"0.55"},"down","no"]
["MSTRG.14650","DOCK8","ENST00000453981;ENST00000432829;MSTRG.14650.7;ENST00000495184;ENST00000478380;ENST00000474772;ENST00000479404;ENST00000382341;ENST00000493666;ENST00000483757;ENST00000382331;ENST00000469197;ENST00000487230;ENST00000382329;ENST00000524396;ENST00000469391;ENST00000462618","GO:0016020(membrane);GO:0007264(small GTPase mediated signal transduction);GO:0043547(positive regulation of GTPase activity);GO:0005515(protein binding);GO:0005085(guanyl-nucleotide exchange factor activity);GO:0005829(cytosol);GO:0007596(blood coagulation);GO:0001771(immunological synapse formation);GO:0036336(dendritic cell migration);GO:0061485(memory T cell proliferation);GO:0070233(negative regulation of T cell apoptotic process);GO:0031252(cell leading edge);GO:0005622(intracellular);GO:0005622(intracellular)","NA","NA","NA","dedicator of cytokinesis 8 [Source:HGNC Symbol;Acc:HGNC:19191]",{"v":29.7310494827336,"d":"29.73"},{"v":10.3991637026262,"d":"10.40"},{"v":2.85898465808605,"d":"2.86"},{"v":1.51550287818427,"d":"1.52"},{"v":0.0604121408617067,"d":"0.06"},{"v":0.550132714438969,"d":"0.55"},"up","no"]
["MSTRG.11142","HACD2","ENST00000383657;ENST00000469317;ENST00000471236;ENST00000480081;ENST00000493515","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016829(lyase activity);GO:0006629(lipid metabolic process);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0006631(fatty acid metabolic process);GO:0006633(fatty acid biosynthetic process);GO:0042761(very long-chain fatty acid biosynthetic process);GO:0005515(protein binding);GO:0035338(long-chain fatty-acyl-CoA biosynthetic process);GO:0030176(integral component of endoplasmic reticulum membrane);GO:0080023(3R-hydroxyacyl-CoA dehydratase activity);GO:0102343(3-hydroxy-arachidoyl-CoA dehydratase activity);GO:0102344(3-hydroxy-behenoyl-CoA dehydratase activity);GO:0102345(3-hydroxy-lignoceroyl-CoA dehydratase activity);GO:0019899(enzyme binding);GO:0030148(sphingolipid biosynthetic process);GO:0018812(3-hydroxyacyl-CoA dehydratase activity);GO:0030497(fatty acid elongation);GO:0030497(fatty acid elongation)","00062(Fatty acid elongation);01040(Biosynthesis of unsaturated fatty acids);01040(Biosynthesis of unsaturated fatty acids)","K10703","EC:4.2.1.134","3-hydroxyacyl-CoA dehydratase 2 [Source:HGNC Symbol;Acc:HGNC:9640]",{"v":3.98062898056438,"d":"3.98"},{"v":1.38234379443095,"d":"1.38"},{"v":2.87962299726099,"d":"2.88"},{"v":1.52587994514524,"d":"1.53"},{"v":0.0604468564216072,"d":"0.06"},{"v":0.550132714438969,"d":"0.55"},"up","no"]
["ENSG00000070785","EIF2B3","ENST00000360403;ENST00000372183;ENST00000480675;ENST00000486491;ENST00000477953;ENST00000620860","GO:0005737(cytoplasm);GO:0003743(translation initiation factor activity);GO:0006412(translation);GO:0006413(translational initiation);GO:0009058(biosynthetic process);GO:0043547(positive regulation of GTPase activity);GO:0016779(nucleotidyltransferase activity);GO:0005085(guanyl-nucleotide exchange factor activity);GO:0005515(protein binding);GO:0005829(cytosol);GO:0009408(response to heat);GO:0005851(eukaryotic translation initiation factor 2B complex);GO:0032057(negative regulation of translational initiation in response to stress);GO:0009749(response to glucose);GO:0008135(translation factor activity, RNA binding);GO:0043434(response to peptide hormone);GO:0014003(oligodendrocyte development);GO:0051716(cellular response to stimulus);GO:0021766(hippocampus development);GO:0021766(hippocampus development)","03013(RNA transport);03013(RNA transport)","K03241","NA","eukaryotic translation initiation factor 2B subunit gamma [Source:HGNC Symbol;Acc:HGNC:3259]",{"v":1.00312335180299,"d":"1.00"},{"v":2.01300162474348,"d":"2.01"},{"v":0.498322176928605,"d":"0.50"},{"v":-1.00484931489967,"d":"-1.00"},{"v":0.060646336714992,"d":"0.06"},{"v":0.551458323133372,"d":"0.55"},"down","no"]
["MSTRG.5906","N4BP1","ENST00000262384;ENST00000564124;ENST00000565638;ENST00000569027;ENST00000564710;ENST00000565423","GO:0005634(nucleus);GO:0005515(protein binding);GO:0005730(nucleolus);GO:0032435(negative regulation of proteasomal ubiquitin-dependent protein catabolic process);GO:0016605(PML body);GO:0031397(negative regulation of protein ubiquitination);GO:0034644(cellular response to UV);GO:0034644(cellular response to UV)","NA","NA","NA","NEDD4 binding protein 1 [Source:HGNC Symbol;Acc:HGNC:29850]",{"v":14.4341627637454,"d":"14.43"},{"v":5.05178189501212,"d":"5.05"},{"v":2.85724187301059,"d":"2.86"},{"v":1.5146231693589,"d":"1.51"},{"v":0.0607281513462751,"d":"0.06"},{"v":0.551458323133372,"d":"0.55"},"up","no"]
["MSTRG.7649","C19orf35","ENST00000342063","GO:0006468(protein phosphorylation);GO:0015629(actin cytoskeleton);GO:0004672(protein kinase activity);GO:0005925(focal adhesion)","NA","NA","NA","chromosome 19 open reading frame 35 [Source:HGNC Symbol;Acc:HGNC:24793]",{"v":4.921195,"d":"4.92"},{"v":1.707952,"d":"1.71"},{"v":2.88134268410353,"d":"2.88"},{"v":1.52674125343644,"d":"1.53"},{"v":0.0607349690250222,"d":"0.06"},{"v":0.551458323133372,"d":"0.55"},"up","no"]
["MSTRG.15368","PBDC1","ENST00000373358;ENST00000373357","GO:0005737(cytoplasm);GO:0003674(molecular_function);GO:0008150(biological_process);GO:0005575(cellular_component);GO:0005575(cellular_component)","NA","NA","NA","polysaccharide biosynthesis domain containing 1 [Source:HGNC Symbol;Acc:HGNC:28790]",{"v":3.19060653705246,"d":"3.19"},{"v":6.35816190674438,"d":"6.36"},{"v":0.501812722583872,"d":"0.50"},{"v":-0.994779046667219,"d":"-0.99"},{"v":0.0607880584067382,"d":"0.06"},{"v":0.551509158029258,"d":"0.55"},"down","no"]
["ENSG00000124444","ZNF576","ENST00000336564;ENST00000529930;ENST00000525771;ENST00000595041;ENST00000391965;ENST00000528387","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0005515(protein binding)","NA","NA","NA","zinc finger protein 576 [Source:HGNC Symbol;Acc:HGNC:28357]",{"v":0.550735028727377,"d":"0.55"},{"v":1.12747670841712,"d":"1.13"},{"v":0.488466878841836,"d":"0.49"},{"v":-1.03366735326815,"d":"-1.03"},{"v":0.0608916192571668,"d":"0.06"},{"v":0.551674929256295,"d":"0.55"},"down","no"]
["MSTRG.13836","AP1S1","ENST00000337619;ENST00000443943","GO:0006810(transport);GO:0016020(membrane);GO:0008565(protein transporter activity);GO:0006886(intracellular protein transport);GO:0015031(protein transport);GO:0016192(vesicle-mediated transport);GO:0042147(retrograde transport, endosome to Golgi);GO:0005794(Golgi apparatus);GO:0005829(cytosol);GO:0030117(membrane coat);GO:0043195(terminal bouton);GO:0043231(intracellular membrane-bounded organelle);GO:0030659(cytoplasmic vesicle membrane);GO:0031410(cytoplasmic vesicle);GO:0005905(clathrin-coated pit);GO:0070062(extracellular exosome);GO:0009615(response to virus);GO:0019886(antigen processing and presentation of exogenous peptide antigen via MHC class II);GO:0032588(trans-Golgi network membrane);GO:0000139(Golgi membrane);GO:0005765(lysosomal membrane);GO:0050690(regulation of defense response to virus by virus);GO:0030669(clathrin-coated endocytic vesicle membrane);GO:0006898(receptor-mediated endocytosis);GO:0030121(AP-1 adaptor complex);GO:0030121(AP-1 adaptor complex)","04142(Lysosome);04142(Lysosome)","K12394","NA","adaptor related protein complex 1 sigma 1 subunit [Source:HGNC Symbol;Acc:HGNC:559]",{"v":2.53142429759584,"d":"2.53"},{"v":5.0261872488629,"d":"5.03"},{"v":0.503647033478217,"d":"0.50"},{"v":-0.989515078317058,"d":"-0.99"},{"v":0.0609940370394601,"d":"0.06"},{"v":0.551674929256295,"d":"0.55"},"down","no"]
["MSTRG.15287","PQBP1","ENST00000474671;ENST00000447146;ENST00000376563;ENST00000477997;ENST00000472742;ENST00000443648;ENST00000470062;ENST00000465859;ENST00000463529;ENST00000396763;ENST00000486150;ENST00000218224;ENST00000376566;ENST00000247140;ENST00000473764;ENST00000470059","GO:0006397(mRNA processing);GO:0008380(RNA splicing);GO:0005634(nucleus);GO:0016607(nuclear speck);GO:0005829(cytosol);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0005515(protein binding);GO:0005654(nucleoplasm);GO:0003677(DNA binding);GO:0003713(transcription coactivator activity);GO:0031175(neuron projection development);GO:0000398(mRNA splicing, via spliceosome);GO:0043021(ribonucleoprotein complex binding);GO:0000380(alternative mRNA splicing, via spliceosome);GO:0043484(regulation of RNA splicing);GO:0034063(stress granule assembly);GO:0048814(regulation of dendrite morphogenesis);GO:0005737(cytoplasm);GO:0010494(cytoplasmic stress granule);GO:0071598(neuronal ribonucleoprotein granule);GO:0071598(neuronal ribonucleoprotein granule)","03040(Spliceosome);03040(Spliceosome)","K12865","NA","polyglutamine binding protein 1 [Source:HGNC Symbol;Acc:HGNC:9330]",{"v":8.59516830267998,"d":"8.60"},{"v":16.9686621387283,"d":"16.97"},{"v":0.506531878141581,"d":"0.51"},{"v":-0.981275028250767,"d":"-0.98"},{"v":0.0609989512520886,"d":"0.06"},{"v":0.551674929256295,"d":"0.55"},"down","no"]
["MSTRG.6759","PSMB3","ENST00000619426;ENST00000614132;ENST00000613870;ENST00000620309;ENST00000618159","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016787(hydrolase activity);GO:0005515(protein binding);GO:0008233(peptidase activity);GO:0006508(proteolysis);GO:0000502(proteasome complex);GO:0043161(proteasome-mediated ubiquitin-dependent protein catabolic process);GO:0004175(endopeptidase activity);GO:0004298(threonine-type endopeptidase activity);GO:0051603(proteolysis involved in cellular protein catabolic process);GO:0005839(proteasome core complex);GO:0038095(Fc-epsilon receptor signaling pathway);GO:0019774(proteasome core complex, beta-subunit complex);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0000165(MAPK cascade);GO:0000209(protein polyubiquitination);GO:0002223(stimulatory C-type lectin receptor signaling pathway);GO:0002479(antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent);GO:0006521(regulation of cellular amino acid metabolic process);GO:0010972(negative regulation of G2/M transition of mitotic cell cycle);GO:0016579(protein deubiquitination);GO:0031145(anaphase-promoting complex-dependent catabolic process);GO:0031146(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process);GO:0033209(tumor necrosis factor-mediated signaling pathway);GO:0038061(NIK/NF-kappaB signaling);GO:0043488(regulation of mRNA stability);GO:0043687(post-translational protein modification);GO:0050852(T cell receptor signaling pathway);GO:0051437(positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition);GO:0055085(transmembrane transport);GO:0060071(Wnt signaling pathway, planar cell polarity pathway);GO:0061418(regulation of transcription from RNA polymerase II promoter in response to hypoxia);GO:0090090(negative regulation of canonical Wnt signaling pathway);GO:0090263(positive regulation of canonical Wnt signaling pathway);GO:1902036(regulation of hematopoietic stem cell differentiation);GO:0016032(viral process);GO:0051436(negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle);GO:0051436(negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle)","03050(Proteasome);03050(Proteasome)","K02735","EC:3.4.25.1","proteasome subunit beta 3 [Source:HGNC Symbol;Acc:HGNC:9540]",{"v":32.6249193884648,"d":"32.62"},{"v":64.1130051942324,"d":"64.11"},{"v":0.508865857864977,"d":"0.51"},{"v":-0.974642697325983,"d":"-0.97"},{"v":0.0611046726612302,"d":"0.06"},{"v":0.551674929256295,"d":"0.55"},"down","no"]
["MSTRG.15451","FAM45BP","ENST00000592932;ENST00000408950","NA","NA","NA","NA","family with sequence similarity 45 member B, pseudogene [Source:HGNC Symbol;Acc:HGNC:30886]",{"v":1.632853,"d":"1.63"},{"v":3.27608040517241,"d":"3.28"},{"v":0.498416643688593,"d":"0.50"},{"v":-1.00457584962722,"d":"-1.00"},{"v":0.0611079458935066,"d":"0.06"},{"v":0.551674929256295,"d":"0.55"},"down","no"]
["ENSG00000255274","TMPRSS4-AS1","ENST00000636151","GO:0016020(membrane);GO:0016021(integral component of membrane)","NA","NA","NA","TMPRSS4 antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:44179]",{"v":0.201844350225524,"d":"0.20"},{"v":0.424576329795702,"d":"0.42"},{"v":0.475401797181316,"d":"0.48"},{"v":-1.07278073771625,"d":"-1.07"},{"v":0.0611283736595372,"d":"0.06"},{"v":0.551674929256295,"d":"0.55"},"down","no"]
["ENSG00000112137","PHACTR1","ENST00000379350;ENST00000379335;ENST00000379329;ENST00000332995;ENST00000406205;ENST00000489548;ENST00000481706","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0003779(actin binding);GO:0005829(cytosol);GO:0050790(regulation of catalytic activity);GO:0043086(negative regulation of catalytic activity);GO:0030054(cell junction);GO:0045202(synapse);GO:0031532(actin cytoskeleton reorganization);GO:0019888(protein phosphatase regulator activity);GO:0004864(protein phosphatase inhibitor activity);GO:0008157(protein phosphatase 1 binding);GO:0048870(cell motility);GO:0043149(stress fiber assembly);GO:0031032(actomyosin structure organization);GO:0031032(actomyosin structure organization)","NA","NA","NA","phosphatase and actin regulator 1 [Source:HGNC Symbol;Acc:HGNC:20990]",{"v":0.23702057153063,"d":"0.24"},{"v":0.479767983925701,"d":"0.48"},{"v":0.494031655866674,"d":"0.49"},{"v":-1.01732460712872,"d":"-1.02"},{"v":0.0611675626886372,"d":"0.06"},{"v":0.551674929256295,"d":"0.55"},"down","no"]
["MSTRG.2368","AC090559.1","ENST00000527426;ENST00000532340;ENST00000532943","NA","NA","NA","NA",null,{"v":3.60401090116801,"d":"3.60"},{"v":1.22199516891285,"d":"1.22"},{"v":2.94928408299218,"d":"2.95"},{"v":1.56036479336767,"d":"1.56"},{"v":0.0611863694895469,"d":"0.06"},{"v":0.551674929256295,"d":"0.55"},"up","no"]
["MSTRG.968","MRPL9;AL589765.4","ENST00000368830;ENST00000368829;ENST00000478926;ENST00000462783;ENST00000512280;ENST00000467306;ENST00000461182;ENST00000468006;ENST00000486707;ENST00000481777","GO:0003723(RNA binding);GO:0006412(translation);GO:0005739(mitochondrion);GO:0030529(intracellular ribonucleoprotein complex);GO:0005622(intracellular);GO:0003735(structural constituent of ribosome);GO:0005840(ribosome);GO:0005515(protein binding);GO:0005743(mitochondrial inner membrane);GO:0070125(mitochondrial translational elongation);GO:0070126(mitochondrial translational termination);GO:0005761(mitochondrial ribosome);GO:0005762(mitochondrial large ribosomal subunit);GO:0005762(mitochondrial large ribosomal subunit)","03010(Ribosome);03010(Ribosome)","K02939","NA","mitochondrial ribosomal protein L9 [Source:HGNC Symbol;Acc:HGNC:14277]",{"v":5.56946505346821,"d":"5.57"},{"v":11.0244679436416,"d":"11.02"},{"v":0.505191278340141,"d":"0.51"},{"v":-0.985098362341549,"d":"-0.99"},{"v":0.0612908092362753,"d":"0.06"},{"v":0.552187872506489,"d":"0.55"},"down","no"]
["MSTRG.6408","CHD3","ENST00000358181;ENST00000481999;ENST00000330494;ENST00000380358;ENST00000572579;ENST00000479080;ENST00000466233;ENST00000449744;ENST00000473376;ENST00000452447;ENST00000574022;ENST00000573936;ENST00000470531;ENST00000572750;ENST00000571249;ENST00000439235","GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0005730(nucleolus);GO:0016787(hydrolase activity);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0016569(covalent chromatin modification);GO:0016575(histone deacetylation);GO:0004386(helicase activity);GO:0032508(DNA duplex unwinding);GO:0003677(DNA binding);GO:0008270(zinc ion binding);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0005815(microtubule organizing center);GO:0006325(chromatin organization);GO:0007098(centrosome cycle);GO:0005813(centrosome);GO:0007051(spindle organization);GO:0016581(NuRD complex);GO:0005654(nucleoplasm);GO:1901796(regulation of signal transduction by p53 class mediator);GO:0004407(histone deacetylase activity);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0004003(ATP-dependent DNA helicase activity);GO:0006333(chromatin assembly or disassembly);GO:0006333(chromatin assembly or disassembly)","NA","NA","NA","chromodomain helicase DNA binding protein 3 [Source:HGNC Symbol;Acc:HGNC:1918]",{"v":11.0672073009838,"d":"11.07"},{"v":3.87969481686821,"d":"3.88"},{"v":2.85259738803825,"d":"2.85"},{"v":1.51227614114724,"d":"1.51"},{"v":0.0614008334557614,"d":"0.06"},{"v":0.552375766294562,"d":"0.55"},"up","no"]
["ENSG00000118762","PKD2","ENST00000237596;ENST00000506727;ENST00000508588;ENST00000502363;ENST00000511337","GO:0008285(negative regulation of cell proliferation);GO:0071158(positive regulation of cell cycle arrest);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0005737(cytoplasm);GO:2000134(negative regulation of G1/S transition of mitotic cell cycle);GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0046872(metal ion binding);GO:0005783(endoplasmic reticulum);GO:0005509(calcium ion binding);GO:0005789(endoplasmic reticulum membrane);GO:0005244(voltage-gated ion channel activity);GO:0005267(potassium channel activity);GO:0006811(ion transport);GO:0006813(potassium ion transport);GO:0034765(regulation of ion transmembrane transport);GO:0071805(potassium ion transmembrane transport);GO:0005886(plasma membrane);GO:0042995(cell projection);GO:0005515(protein binding);GO:0006816(calcium ion transport);GO:0030659(cytoplasmic vesicle membrane);GO:0031410(cytoplasmic vesicle);GO:0005262(calcium channel activity);GO:0070588(calcium ion transmembrane transport);GO:0042802(identical protein binding);GO:0005887(integral component of plasma membrane);GO:0060078(regulation of postsynaptic membrane potential);GO:0005929(cilium);GO:0070062(extracellular exosome);GO:0007507(heart development);GO:0016323(basolateral plasma membrane);GO:0060170(ciliary membrane);GO:0042803(protein homodimerization activity);GO:0030027(lamellipodium);GO:0044325(ion channel binding);GO:0035725(sodium ion transmembrane transport);GO:0051289(protein homotetramerization);GO:0001947(heart looping);GO:0007368(determination of left/right symmetry);GO:0021510(spinal cord development);GO:0051209(release of sequestered calcium ion into cytosol);GO:0051117(ATPase binding);GO:0005102(receptor binding);GO:0005911(cell-cell junction);GO:0060315(negative regulation of ryanodine-sensitive calcium-release channel activity);GO:0051298(centrosome duplication);GO:0050982(detection of mechanical stimulus);GO:0051219(phosphoprotein binding);GO:0001889(liver development);GO:0071320(cellular response to cAMP);GO:0071277(cellular response to calcium ion);GO:0045429(positive regulation of nitric oxide biosynthetic process);GO:0042805(actinin binding);GO:0005249(voltage-gated potassium channel activity);GO:0071910(determination of liver left/right asymmetry);GO:0072686(mitotic spindle);GO:0005248(voltage-gated sodium channel activity);GO:0036064(ciliary basal body);GO:0031514(motile cilium);GO:0021915(neural tube development);GO:0015271(outward rectifier potassium channel activity);GO:0072177(mesonephric duct development);GO:0031659(positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle);GO:0042127(regulation of cell proliferation);GO:0034614(cellular response to reactive oxygen species);GO:0001658(branching involved in ureteric bud morphogenesis);GO:0007050(cell cycle arrest);GO:0090279(regulation of calcium ion import);GO:0007259(JAK-STAT cascade);GO:0061333(renal tubule morphogenesis);GO:0008092(cytoskeletal protein binding);GO:0030814(regulation of cAMP metabolic process);GO:0072075(metanephric mesenchyme development);GO:0072284(metanephric S-shaped body morphogenesis);GO:0072218(metanephric ascending thin limb development);GO:0060674(placenta blood vessel development);GO:0097730(non-motile cilium);GO:0005245(voltage-gated calcium channel activity);GO:0001892(embryonic placenta development);GO:0042994(cytoplasmic sequestering of transcription factor);GO:0072164(mesonephric tubule development);GO:0002133(polycystin complex);GO:0009925(basal plasma membrane);GO:0031941(filamentous actin);GO:0015267(channel activity);GO:0022843(voltage-gated cation channel activity);GO:0043398(HLH domain binding);GO:0048763(calcium-induced calcium release activity);GO:0051371(muscle alpha-actinin binding);GO:0051393(alpha-actinin binding);GO:0001822(kidney development);GO:0003127(detection of nodal flow);GO:0006874(cellular calcium ion homeostasis);GO:0007204(positive regulation of cytosolic calcium ion concentration);GO:0010628(positive regulation of gene expression);GO:0031587(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity);GO:0035502(metanephric part of ureteric bud development);GO:0035904(aorta development);GO:0061441(renal artery morphogenesis);GO:0071464(cellular response to hydrostatic pressure);GO:0071470(cellular response to osmotic stress);GO:0071498(cellular response to fluid shear stress);GO:0072001(renal system development);GO:0072208(metanephric smooth muscle tissue development);GO:0072214(metanephric cortex development);GO:0072219(metanephric cortical collecting duct development);GO:0072235(metanephric distal tubule development);GO:0045180(basal cortex);GO:0071458(integral component of cytoplasmic side of endoplasmic reticulum membrane);GO:0071556(integral component of lumenal side of endoplasmic reticulum membrane);GO:0071556(integral component of lumenal side of endoplasmic reticulum membrane)","NA","NA","NA","polycystin 2, transient receptor potential cation channel [Source:HGNC Symbol;Acc:HGNC:9009]",{"v":0.938062895962168,"d":"0.94"},{"v":0.315384033830484,"d":"0.32"},{"v":2.97435125224623,"d":"2.97"},{"v":1.57257503069584,"d":"1.57"},{"v":0.0614999933251531,"d":"0.06"},{"v":0.552375766294562,"d":"0.55"},"up","no"]
["ENSG00000163606","CD200R1","ENST00000308611;ENST00000440122;ENST00000471858;ENST00000490004","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0050776(regulation of immune response);GO:0009897(external side of plasma membrane);GO:0016032(viral process);GO:0004872(receptor activity);GO:0043235(receptor complex);GO:0043235(receptor complex)","05167(Kaposi's sarcoma-associated herpesvirus infection);05167(Kaposi's sarcoma-associated herpesvirus infection)","K21668","NA","CD200 receptor 1 [Source:HGNC Symbol;Acc:HGNC:24235]",{"v":0.902710775672215,"d":"0.90"},{"v":1.8005937234315,"d":"1.80"},{"v":0.501340621110166,"d":"0.50"},{"v":-0.996136961704788,"d":"-1.00"},{"v":0.0615847990498598,"d":"0.06"},{"v":0.552375766294562,"d":"0.55"},"down","no"]
["MSTRG.1067","GON4L","ENST00000271883;ENST00000361040;ENST00000483032;ENST00000471341;ENST00000368331;ENST00000473267;ENST00000615926;ENST00000622608;ENST00000466224;ENST00000468867;ENST00000497369;ENST00000496021;ENST00000490801;ENST00000437809;ENST00000467009;ENST00000488251;ENST00000482386;ENST00000460075","GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0003714(transcription corepressor activity);GO:0045892(negative regulation of transcription, DNA-templated);GO:0016604(nuclear body);GO:0030183(B cell differentiation);GO:0030183(B cell differentiation)","NA","NA","NA","gon-4 like [Source:HGNC Symbol;Acc:HGNC:25973]",{"v":4.13706843879001,"d":"4.14"},{"v":1.44689022194368,"d":"1.45"},{"v":2.85928287858113,"d":"2.86"},{"v":1.51565335775767,"d":"1.52"},{"v":0.0616281283098439,"d":"0.06"},{"v":0.552375766294562,"d":"0.55"},"up","no"]
["MSTRG.13492","NDUFA4","ENST00000339600;ENST00000492822;ENST00000482299;ENST00000486007;ENST00000470761;ENST00000463308","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0055114(oxidation-reduction process);GO:0005743(mitochondrial inner membrane);GO:0005739(mitochondrion);GO:1902600(hydrogen ion transmembrane transport);GO:0070469(respiratory chain);GO:0005751(mitochondrial respiratory chain complex IV);GO:0070062(extracellular exosome);GO:0008137(NADH dehydrogenase (ubiquinone) activity);GO:0006120(mitochondrial electron transport, NADH to ubiquinone);GO:0005747(mitochondrial respiratory chain complex I);GO:0032403(protein complex binding);GO:0005515(protein binding);GO:0004129(cytochrome-c oxidase activity);GO:0006123(mitochondrial electron transport, cytochrome c to oxygen);GO:0006123(mitochondrial electron transport, cytochrome c to oxygen)","00190(Oxidative phosphorylation);04723(Retrograde endocannabinoid signaling);05010(Alzheimer's disease);05012(Parkinson's disease);05016(Huntington's disease);04932(Non-alcoholic fatty liver disease (NAFLD));04932(Non-alcoholic fatty liver disease (NAFLD))","K03948","NA","NDUFA4, mitochondrial complex associated [Source:HGNC Symbol;Acc:HGNC:7687]",{"v":6.14141962260967,"d":"6.14"},{"v":12.0666993312711,"d":"12.07"},{"v":0.508956049538257,"d":"0.51"},{"v":-0.974387015896521,"d":"-0.97"},{"v":0.061685538478645,"d":"0.06"},{"v":0.552375766294562,"d":"0.55"},"down","no"]
["MSTRG.14627","HGH1","ENST00000347708;ENST00000530409;ENST00000530074;ENST00000525101;ENST00000534255","GO:0003674(molecular_function);GO:0008150(biological_process);GO:0005575(cellular_component);GO:0005575(cellular_component)","NA","NA","NA","HGH1 homolog [Source:HGNC Symbol;Acc:HGNC:24161]",{"v":2.52609293603412,"d":"2.53"},{"v":0.870459046908315,"d":"0.87"},{"v":2.90202387465127,"d":"2.90"},{"v":1.53705938835687,"d":"1.54"},{"v":0.0617001406856069,"d":"0.06"},{"v":0.552375766294562,"d":"0.55"},"up","no"]
["MSTRG.2855","ZBTB16","ENST00000335953;ENST00000541602;ENST00000539918;ENST00000545851;ENST00000544220;ENST00000535700;ENST00000535509","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0016607(nuclear speck);GO:0046872(metal ion binding);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0016567(protein ubiquitination);GO:0003677(DNA binding);GO:0042803(protein homodimerization activity);GO:0005515(protein binding);GO:0006915(apoptotic process);GO:0003690(double-stranded DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0008022(protein C-terminus binding);GO:0019904(protein domain specific binding);GO:0001501(skeletal system development);GO:0001823(mesonephros development);GO:0007417(central nervous system development);GO:0008285(negative regulation of cell proliferation);GO:0009880(embryonic pattern specification);GO:0009952(anterior/posterior pattern specification);GO:0030097(hemopoiesis);GO:0034504(protein localization to nucleus);GO:0035116(embryonic hindlimb morphogenesis);GO:0035136(forelimb morphogenesis);GO:0035137(hindlimb morphogenesis);GO:0042733(embryonic digit morphogenesis);GO:0043065(positive regulation of apoptotic process);GO:0045638(negative regulation of myeloid cell differentiation);GO:0048133(male germ-line stem cell asymmetric division);GO:0051138(positive regulation of NK T cell differentiation);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0045893(positive regulation of transcription, DNA-templated);GO:0042802(identical protein binding);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0043687(post-translational protein modification);GO:0032332(positive regulation of chondrocyte differentiation);GO:0051216(cartilage development);GO:0045892(negative regulation of transcription, DNA-templated);GO:0016605(PML body);GO:0016604(nuclear body);GO:0045600(positive regulation of fat cell differentiation);GO:0000980(RNA polymerase II distal enhancer sequence-specific DNA binding);GO:0030099(myeloid cell differentiation);GO:0061036(positive regulation of cartilage development);GO:0045778(positive regulation of ossification);GO:0001206(transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding);GO:0017053(transcriptional repressor complex);GO:0017053(transcriptional repressor complex)","05200(Pathways in cancer);05202(Transcriptional misregulation in cancers);05221(Acute myeloid leukemia);05221(Acute myeloid leukemia)","K10055","NA","zinc finger and BTB domain containing 16 [Source:HGNC Symbol;Acc:HGNC:12930]",{"v":1.31898607093534,"d":"1.32"},{"v":0.458716327683616,"d":"0.46"},{"v":2.87538505026807,"d":"2.88"},{"v":1.52375516402768,"d":"1.52"},{"v":0.0617210425606847,"d":"0.06"},{"v":0.552375766294562,"d":"0.55"},"up","no"]
["MSTRG.10969","DUSP7","ENST00000495880;ENST00000469623","GO:0005737(cytoplasm);GO:0016787(hydrolase activity);GO:0008138(protein tyrosine/serine/threonine phosphatase activity);GO:0016791(phosphatase activity);GO:0006470(protein dephosphorylation);GO:0016311(dephosphorylation);GO:0005829(cytosol);GO:0004721(phosphoprotein phosphatase activity);GO:0005515(protein binding);GO:0017017(MAP kinase tyrosine/serine/threonine phosphatase activity);GO:0000188(inactivation of MAPK activity);GO:0004725(protein tyrosine phosphatase activity);GO:0005654(nucleoplasm);GO:0000165(MAPK cascade);GO:0035335(peptidyl-tyrosine dephosphorylation);GO:0000187(activation of MAPK activity);GO:0043407(negative regulation of MAP kinase activity);GO:0043407(negative regulation of MAP kinase activity)","04010(MAPK signaling pathway);04010(MAPK signaling pathway)","K04459","EC:3.1.3.16;EC:3.1.3.48","dual specificity phosphatase 7 [Source:HGNC Symbol;Acc:HGNC:3073]",{"v":6.69300659826487,"d":"6.69"},{"v":2.34580149362606,"d":"2.35"},{"v":2.85318541080774,"d":"2.85"},{"v":1.51257350176063,"d":"1.51"},{"v":0.0617305787649859,"d":"0.06"},{"v":0.552375766294562,"d":"0.55"},"up","no"]
["MSTRG.12003","NIPBL","ENST00000448238;ENST00000282516;ENST00000514335;ENST00000513819;ENST00000503274","GO:0003151(outflow tract morphogenesis);GO:0005634(nucleus);GO:0006974(cellular response to DNA damage stimulus);GO:0007049(cell cycle);GO:0003682(chromatin binding);GO:0010468(regulation of gene expression);GO:0005515(protein binding);GO:0005654(nucleoplasm);GO:0070062(extracellular exosome);GO:0008022(protein C-terminus binding);GO:0007064(mitotic sister chromatid cohesion);GO:0047485(protein N-terminus binding);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0045892(negative regulation of transcription, DNA-templated);GO:0035115(embryonic forelimb morphogenesis);GO:0003007(heart morphogenesis);GO:0042826(histone deacetylase binding);GO:0007605(sensory perception of sound);GO:0007420(brain development);GO:0045995(regulation of embryonic development);GO:0034613(cellular protein localization);GO:0060325(face morphogenesis);GO:0070087(chromo shadow domain binding);GO:0031065(positive regulation of histone deacetylation);GO:0036033(mediator complex binding);GO:0001656(metanephros development);GO:0007507(heart development);GO:0019827(stem cell population maintenance);GO:0034088(maintenance of mitotic sister chromatid cohesion);GO:0035136(forelimb morphogenesis);GO:0035261(external genitalia morphogenesis);GO:0040018(positive regulation of multicellular organism growth);GO:0042471(ear morphogenesis);GO:0042634(regulation of hair cycle);GO:0045444(fat cell differentiation);GO:0045778(positive regulation of ossification);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0048557(embryonic digestive tract morphogenesis);GO:0048589(developmental growth);GO:0048592(eye morphogenesis);GO:0048638(regulation of developmental growth);GO:0048701(embryonic cranial skeleton morphogenesis);GO:0048703(embryonic viscerocranium morphogenesis);GO:0050890(cognition);GO:0061010(gall bladder development);GO:0061038(uterus morphogenesis);GO:0071481(cellular response to X-ray);GO:0000785(chromatin);GO:0032116(SMC loading complex);GO:0032116(SMC loading complex)","NA","NA","NA","NIPBL, cohesin loading factor [Source:HGNC Symbol;Acc:HGNC:28862]",{"v":12.0051479246548,"d":"12.01"},{"v":4.21608461489345,"d":"4.22"},{"v":2.84746370655044,"d":"2.85"},{"v":1.50967745362316,"d":"1.51"},{"v":0.0617397524025094,"d":"0.06"},{"v":0.552375766294562,"d":"0.55"},"up","no"]
["ENSG00000272886","DCP1A","ENST00000610213;ENST00000294241;ENST00000558034;ENST00000560076","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0016787(hydrolase activity);GO:0008047(enzyme activator activity);GO:0005515(protein binding);GO:0000932(P-body);GO:0000290(deadenylation-dependent decapping of nuclear-transcribed mRNA);GO:0043085(positive regulation of catalytic activity);GO:0042802(identical protein binding);GO:0005829(cytosol);GO:0043488(regulation of mRNA stability);GO:0003729(mRNA binding);GO:1903608(protein localization to cytoplasmic stress granule);GO:0043928(exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay);GO:0000184(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay);GO:0030234(enzyme regulator activity);GO:0031087(deadenylation-independent decapping of nuclear-transcribed mRNA);GO:0019894(kinesin binding);GO:0019894(kinesin binding)","03018(RNA degradation);03018(RNA degradation)","K12610","EC:3.-.-.-","decapping mRNA 1A [Source:HGNC Symbol;Acc:HGNC:18714]",{"v":5.01182153239758,"d":"5.01"},{"v":1.75482318149176,"d":"1.75"},{"v":2.8560265132451,"d":"2.86"},{"v":1.51400937234659,"d":"1.51"},{"v":0.0618873479814166,"d":"0.06"},{"v":0.553270032415851,"d":"0.55"},"up","no"]
["ENSG00000139517","LNX2","ENST00000316334","GO:0046872(metal ion binding);GO:0005515(protein binding);GO:0030165(PDZ domain binding);GO:0051260(protein homooligomerization)","NA","NA","NA","ligand of numb-protein X 2 [Source:HGNC Symbol;Acc:HGNC:20421]",{"v":2.153756,"d":"2.15"},{"v":0.748096,"d":"0.75"},{"v":2.87898344597485,"d":"2.88"},{"v":1.52555949349369,"d":"1.53"},{"v":0.0619511254963056,"d":"0.06"},{"v":0.55341416952969,"d":"0.55"},"up","no"]
["MSTRG.13608","CDK13","ENST00000340829;ENST00000181839;ENST00000465643;ENST00000484589;ENST00000478563;ENST00000611390","GO:0003723(RNA binding);GO:0006397(mRNA processing);GO:0008380(RNA splicing);GO:0005634(nucleus);GO:0016607(nuclear speck);GO:0005794(Golgi apparatus);GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0005829(cytosol);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0051301(cell division);GO:0005515(protein binding);GO:0005615(extracellular space);GO:0019901(protein kinase binding);GO:0030332(cyclin binding);GO:0000380(alternative mRNA splicing, via spliceosome);GO:2000737(negative regulation of stem cell differentiation);GO:0019908(nuclear cyclin-dependent protein kinase holoenzyme complex);GO:0005576(extracellular region);GO:0005654(nucleoplasm);GO:0008134(transcription factor binding);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0006368(transcription elongation from RNA polymerase II promoter);GO:0016032(viral process);GO:0043312(neutrophil degranulation);GO:0007275(multicellular organism development);GO:1904813(ficolin-1-rich granule lumen);GO:0030097(hemopoiesis);GO:0007088(regulation of mitotic nuclear division);GO:0008284(positive regulation of cell proliferation);GO:0044212(transcription regulatory region DNA binding);GO:0002945(cyclin K-CDK13 complex);GO:0005694(chromosome);GO:0004693(cyclin-dependent protein serine/threonine kinase activity);GO:0008353(RNA polymerase II carboxy-terminal domain kinase activity);GO:0070816(phosphorylation of RNA polymerase II C-terminal domain);GO:0008024(cyclin/CDK positive transcription elongation factor complex);GO:0008024(cyclin/CDK positive transcription elongation factor complex)","NA","NA","NA","cyclin dependent kinase 13 [Source:HGNC Symbol;Acc:HGNC:1733]",{"v":4.82181739849793,"d":"4.82"},{"v":1.69011090438292,"d":"1.69"},{"v":2.85295916735028,"d":"2.85"},{"v":1.51245909866067,"d":"1.51"},{"v":0.062048991565318,"d":"0.06"},{"v":0.55386236667797,"d":"0.55"},"up","no"]
["MSTRG.10675","NUP210","ENST00000254508;ENST00000420141;ENST00000485755;ENST00000479519","GO:0006810(transport);GO:0051028(mRNA transport);GO:0005634(nucleus);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0015031(protein transport);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005643(nuclear pore);GO:0075733(intracellular transport of virus);GO:0043657(host cell);GO:0031965(nuclear membrane);GO:0016032(viral process);GO:0006406(mRNA export from nucleus);GO:0016925(protein sumoylation);GO:0060964(regulation of gene silencing by miRNA);GO:0006110(regulation of glycolytic process);GO:0006409(tRNA export from nucleus);GO:0007077(mitotic nuclear envelope disassembly);GO:0019083(viral transcription);GO:1900034(regulation of cellular response to heat);GO:0005635(nuclear envelope);GO:0046983(protein dimerization activity);GO:0046983(protein dimerization activity)","03013(RNA transport);03013(RNA transport)","K14314","NA","nucleoporin 210 [Source:HGNC Symbol;Acc:HGNC:30052]",{"v":16.9248685397213,"d":"16.92"},{"v":5.95402082938157,"d":"5.95"},{"v":2.84259478169801,"d":"2.84"},{"v":1.50720845423835,"d":"1.51"},{"v":0.0621837169387033,"d":"0.06"},{"v":0.554190580962826,"d":"0.55"},"up","no"]
["MSTRG.1596","VIM-AS1","ENST00000605833;ENST00000437232","NA","NA","NA","NA","VIM antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:44879]",{"v":3.89255864859438,"d":"3.89"},{"v":7.66156696385542,"d":"7.66"},{"v":0.50806299376591,"d":"0.51"},{"v":-0.976920709780897,"d":"-0.98"},{"v":0.0623042767960156,"d":"0.06"},{"v":0.554190580962826,"d":"0.55"},"down","no"]
["MSTRG.10994","PBRM1","ENST00000296302;ENST00000449505;ENST00000458294;ENST00000356770;ENST00000462207;ENST00000409057;ENST00000412587;ENST00000439181;ENST00000409114;ENST00000450271;ENST00000420148;ENST00000423351;ENST00000480064;ENST00000394830;ENST00000337303;ENST00000431678;ENST00000409767","GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0016569(covalent chromatin modification);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0003682(chromatin binding);GO:0008285(negative regulation of cell proliferation);GO:0006338(chromatin remodeling);GO:0000278(mitotic cell cycle);GO:0000228(nuclear chromosome);GO:0090544(BAF-type complex);GO:0090544(BAF-type complex)","05225(Hepatocellular carcinoma);05225(Hepatocellular carcinoma)","K11757","NA","polybromo 1 [Source:HGNC Symbol;Acc:HGNC:30064]",{"v":4.6928937519163,"d":"4.69"},{"v":1.64573120613217,"d":"1.65"},{"v":2.85155542680972,"d":"2.85"},{"v":1.5117490752138,"d":"1.51"},{"v":0.0623617469801859,"d":"0.06"},{"v":0.554190580962826,"d":"0.55"},"up","no"]
["MSTRG.4483","MAX","MSTRG.4483.5;ENST00000618858;ENST00000284165;ENST00000358402;ENST00000394606;MSTRG.4483.6;ENST00000557277;ENST00000553928;ENST00000358664;ENST00000555667;ENST00000246163;ENST00000556443;MSTRG.4483.2;ENST00000555419;ENST00000556702;ENST00000341653;ENST00000553951;ENST00000556979;ENST00000556892;ENST00000554709;ENST00000557746","GO:0005634(nucleus);GO:0046983(protein dimerization activity);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0042995(cell projection);GO:0005515(protein binding);GO:0030425(dendrite);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0005654(nucleoplasm);GO:0003713(transcription coactivator activity);GO:0006366(transcription from RNA polymerase II promoter);GO:0071339(MLL1 complex);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0000082(G1/S transition of mitotic cell cycle);GO:0003712(transcription cofactor activity);GO:0000977(RNA polymerase II regulatory region sequence-specific DNA binding);GO:0090575(RNA polymerase II transcription factor complex);GO:0001227(transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding);GO:0042803(protein homodimerization activity);GO:0032993(protein-DNA complex);GO:0070888(E-box binding);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:0000983(transcription factor activity, RNA polymerase II core promoter sequence-specific);GO:0032403(protein complex binding);GO:0043565(sequence-specific DNA binding);GO:0046982(protein heterodimerization activity);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0006461(protein complex assembly);GO:0009267(cellular response to starvation);GO:0010243(response to organonitrogen compound);GO:0010629(negative regulation of gene expression);GO:0032868(response to insulin);GO:0048678(response to axon injury);GO:0051402(neuron apoptotic process);GO:0060041(retina development in camera-type eye);GO:0071375(cellular response to peptide hormone stimulus);GO:0005737(cytoplasm);GO:0016605(PML body);GO:0016605(PML body)","04010(MAPK signaling pathway);05200(Pathways in cancer);05202(Transcriptional misregulation in cancers);05222(Small cell lung cancer);05222(Small cell lung cancer)","K04453","NA","MYC associated factor X [Source:HGNC Symbol;Acc:HGNC:6913]",{"v":22.3901491717282,"d":"22.39"},{"v":7.86687406423421,"d":"7.87"},{"v":2.84613036752708,"d":"2.85"},{"v":1.50900174629068,"d":"1.51"},{"v":0.0624109804198269,"d":"0.06"},{"v":0.554190580962826,"d":"0.55"},"up","no"]
["ENSG00000137177","KIF13A","ENST00000378814;ENST00000502704;ENST00000378826;ENST00000358380;ENST00000506044;ENST00000503342;ENST00000378843;ENST00000514714;ENST00000502297;ENST00000507576;ENST00000259711;ENST00000505588","GO:0006810(transport);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0015031(protein transport);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0005794(Golgi apparatus);GO:0051301(cell division);GO:0003777(microtubule motor activity);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0007049(cell cycle);GO:0008017(microtubule binding);GO:0000139(Golgi membrane);GO:0005874(microtubule);GO:0007018(microtubule-based movement);GO:0006886(intracellular protein transport);GO:0005813(centrosome);GO:0005815(microtubule organizing center);GO:0030496(midbody);GO:0072383(plus-end-directed vesicle transport along microtubule);GO:0005768(endosome);GO:0008333(endosome to lysosome transport);GO:0030705(cytoskeleton-dependent intracellular transport);GO:0016887(ATPase activity);GO:0010008(endosome membrane);GO:0005871(kinesin complex);GO:0032438(melanosome organization);GO:0000910(cytokinesis);GO:0032588(trans-Golgi network membrane);GO:0035459(cargo loading into vesicle);GO:0043001(Golgi to plasma membrane protein transport);GO:0005622(intracellular);GO:0005623(cell);GO:0003774(motor activity);GO:0003774(motor activity)","NA","NA","NA","kinesin family member 13A [Source:HGNC Symbol;Acc:HGNC:14566]",{"v":4.51685239969441,"d":"4.52"},{"v":1.58629050053928,"d":"1.59"},{"v":2.84743078153645,"d":"2.85"},{"v":1.50966077174977,"d":"1.51"},{"v":0.0624553660340236,"d":"0.06"},{"v":0.554190580962826,"d":"0.55"},"up","no"]
["ENSG00000169981","ZNF35","ENST00000415571;ENST00000396056;ENST00000453164;ENST00000296092","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0048471(perinuclear region of cytoplasm);GO:0007283(spermatogenesis);GO:0043565(sequence-specific DNA binding);GO:0071300(cellular response to retinoic acid);GO:0005623(cell);GO:0005623(cell)","NA","NA","NA","zinc finger protein 35 [Source:HGNC Symbol;Acc:HGNC:13099]",{"v":0.516258083740143,"d":"0.52"},{"v":1.05210118700713,"d":"1.05"},{"v":0.490692425895575,"d":"0.49"},{"v":-1.02710909209183,"d":"-1.03"},{"v":0.0624768127533221,"d":"0.06"},{"v":0.554190580962826,"d":"0.55"},"down","no"]
["MSTRG.3502","CDK4","ENST00000257904;ENST00000551706;ENST00000547853;ENST00000550419;ENST00000546489;ENST00000552254;ENST00000552388;ENST00000552862","GO:0008284(positive regulation of cell proliferation);GO:0048146(positive regulation of fibroblast proliferation);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0005730(nucleolus);GO:0005829(cytosol);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0031965(nuclear membrane);GO:0051301(cell division);GO:0005515(protein binding);GO:0045859(regulation of protein kinase activity);GO:0007049(cell cycle);GO:0004693(cyclin-dependent protein serine/threonine kinase activity);GO:0030332(cyclin binding);GO:0032403(protein complex binding);GO:0002088(lens development in camera-type eye);GO:0007165(signal transduction);GO:0007623(circadian rhythm);GO:0009636(response to toxic substance);GO:0010033(response to organic substance);GO:0010288(response to lead ion);GO:0031100(animal organ regeneration);GO:0032869(cellular response to insulin stimulus);GO:0033574(response to testosterone);GO:0040014(regulation of multicellular organism growth);GO:0042127(regulation of cell proliferation);GO:0043065(positive regulation of apoptotic process);GO:0045727(positive regulation of translation);GO:0045793(positive regulation of cell size);GO:0046626(regulation of insulin receptor signaling pathway);GO:0046890(regulation of lipid biosynthetic process);GO:0050994(regulation of lipid catabolic process);GO:0051726(regulation of cell cycle);GO:0055093(response to hyperoxia);GO:0060612(adipose tissue development);GO:0071222(cellular response to lipopolysaccharide);GO:0071353(cellular response to interleukin-4);GO:1904628(cellular response to phorbol 13-acetate 12-myristate);GO:1904637(cellular response to ionomycin);GO:0000307(cyclin-dependent protein kinase holoenzyme complex);GO:0005667(transcription factor complex);GO:0005923(bicellular tight junction);GO:0043234(protein complex);GO:0048471(perinuclear region of cytoplasm);GO:0097129(cyclin D2-CDK4 complex);GO:0005654(nucleoplasm);GO:0071157(negative regulation of cell cycle arrest);GO:0007275(multicellular organism development);GO:0000785(chromatin);GO:0010971(positive regulation of G2/M transition of mitotic cell cycle);GO:0042493(response to drug);GO:0010468(regulation of gene expression);GO:0016538(cyclin-dependent protein serine/threonine kinase regulator activity);GO:0000082(G1/S transition of mitotic cell cycle);GO:0045787(positive regulation of cell cycle);GO:0045787(positive regulation of cell cycle)","04151(PI3K-Akt signaling pathway);04110(Cell cycle);04115(p53 signaling pathway);04218(Cellular senescence);04530(Tight junction);04660(T cell receptor signaling pathway);05200(Pathways in cancer);05203(Viral carcinogenesis);05212(Pancreatic cancer);05225(Hepatocellular carcinoma);05214(Glioma);05220(Chronic myeloid leukemia);05218(Melanoma);05219(Bladder cancer);05224(Breast cancer);05222(Small cell lung cancer);05223(Non-small cell lung cancer);04933(AGE-RAGE signaling pathway in diabetic complications);05166(HTLV-I infection);05162(Measles);05161(Hepatitis B);05167(Kaposi's sarcoma-associated herpesvirus infection);05165(Human papillomavirus infection);01522(Endocrine resistance);01522(Endocrine resistance)","K02089","EC:2.7.11.22","cyclin dependent kinase 4 [Source:HGNC Symbol;Acc:HGNC:1773]",{"v":3.0164318175505,"d":"3.02"},{"v":5.93824192739899,"d":"5.94"},{"v":0.507967148261965,"d":"0.51"},{"v":-0.977192898228707,"d":"-0.98"},{"v":0.0625186697992097,"d":"0.06"},{"v":0.554190580962826,"d":"0.55"},"down","no"]
["ENSG00000171444","MCC","ENST00000302475;ENST00000408903;ENST00000505604","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0005886(plasma membrane);GO:0042995(cell projection);GO:0005515(protein binding);GO:0016055(Wnt signaling pathway);GO:0030027(lamellipodium);GO:0090090(negative regulation of canonical Wnt signaling pathway);GO:0007165(signal transduction);GO:0004872(receptor activity);GO:0050680(negative regulation of epithelial cell proliferation);GO:0010633(negative regulation of epithelial cell migration);GO:0045184(establishment of protein localization);GO:0045184(establishment of protein localization)","NA","NA","NA","mutated in colorectal cancers [Source:HGNC Symbol;Acc:HGNC:6935]",{"v":0.321988587195235,"d":"0.32"},{"v":0.109727584961846,"d":"0.11"},{"v":2.9344361065378,"d":"2.93"},{"v":1.55308329568224,"d":"1.55"},{"v":0.0625529377121645,"d":"0.06"},{"v":0.554190580962826,"d":"0.55"},"up","no"]
["MSTRG.9767","SLPI","ENST00000338380","GO:0005794(Golgi apparatus);GO:0003677(DNA binding);GO:0005576(extracellular region);GO:0005515(protein binding);GO:0006955(immune response);GO:0005615(extracellular space);GO:0002376(immune system process);GO:0045087(innate immune response);GO:0042742(defense response to bacterium);GO:0030414(peptidase inhibitor activity);GO:0010466(negative regulation of peptidase activity);GO:0003729(mRNA binding);GO:0004866(endopeptidase inhibitor activity);GO:0010951(negative regulation of endopeptidase activity);GO:0070062(extracellular exosome);GO:0032496(response to lipopolysaccharide);GO:0045071(negative regulation of viral genome replication);GO:0004867(serine-type endopeptidase inhibitor activity);GO:0031012(extracellular matrix);GO:0019731(antibacterial humoral response);GO:0043312(neutrophil degranulation);GO:0019899(enzyme binding);GO:0035580(specific granule lumen);GO:0032091(negative regulation of protein binding);GO:0035821(modification of morphology or physiology of other organism)","NA","NA","NA","secretory leukocyte peptidase inhibitor [Source:HGNC Symbol;Acc:HGNC:11092]",{"v":22.06547,"d":"22.07"},{"v":43.224197,"d":"43.22"},{"v":0.510488835686178,"d":"0.51"},{"v":-0.97004868496217,"d":"-0.97"},{"v":0.0625541154674516,"d":"0.06"},{"v":0.554190580962826,"d":"0.55"},"down","no"]
["MSTRG.6502","SMCR8","ENST00000406438","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005654(nucleoplasm);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0043547(positive regulation of GTPase activity);GO:0005515(protein binding);GO:0006914(autophagy);GO:0005085(guanyl-nucleotide exchange factor activity);GO:0019901(protein kinase binding);GO:0017112(Rab guanyl-nucleotide exchange factor activity);GO:0010506(regulation of autophagy);GO:1903432(regulation of TORC1 signaling);GO:1990316(ATG1/ULK1 kinase complex);GO:0032045(guanyl-nucleotide exchange factor complex);GO:0006469(negative regulation of protein kinase activity);GO:0004860(protein kinase inhibitor activity);GO:0010629(negative regulation of gene expression);GO:0016242(negative regulation of macroautophagy);GO:0032008(positive regulation of TOR signaling);GO:1901098(positive regulation of autophagosome maturation);GO:1902902(negative regulation of autophagosome assembly);GO:0000785(chromatin)","NA","NA","NA","Smith-Magenis syndrome chromosome region, candidate 8 [Source:HGNC Symbol;Acc:HGNC:17921]",{"v":8.368482,"d":"8.37"},{"v":2.945762,"d":"2.95"},{"v":2.84085476016053,"d":"2.84"},{"v":1.50632507505002,"d":"1.51"},{"v":0.0625992033988141,"d":"0.06"},{"v":0.554190580962826,"d":"0.55"},"up","no"]
["MSTRG.4456","TMEM30B","ENST00000555868","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005886(plasma membrane);GO:0006869(lipid transport);GO:0005515(protein binding);GO:0070863(positive regulation of protein exit from endoplasmic reticulum)","NA","NA","NA","transmembrane protein 30B [Source:HGNC Symbol;Acc:HGNC:27254]",{"v":0.569264,"d":"0.57"},{"v":0.18951,"d":"0.19"},{"v":3.0038731465358,"d":"3.00"},{"v":1.58682388917444,"d":"1.59"},{"v":0.0626771767738562,"d":"0.06"},{"v":0.554190580962826,"d":"0.55"},"up","no"]
["MSTRG.11460","PAK2","MSTRG.11460.1;ENST00000327134;ENST00000426668;ENST00000481344","GO:0005737(cytoplasm);GO:0005634(nucleus);GO:0016020(membrane);GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0042981(regulation of apoptotic process);GO:0005515(protein binding);GO:0003824(catalytic activity);GO:0008152(metabolic process);GO:0006915(apoptotic process);GO:0048471(perinuclear region of cytoplasm);GO:0038095(Fc-epsilon receptor signaling pathway);GO:0005886(plasma membrane);GO:0042802(identical protein binding);GO:0061098(positive regulation of protein tyrosine kinase activity);GO:0005829(cytosol);GO:0045296(cadherin binding);GO:0040008(regulation of growth);GO:0002223(stimulatory C-type lectin receptor signaling pathway);GO:0050852(T cell receptor signaling pathway);GO:0016032(viral process);GO:0007266(Rho protein signal transduction);GO:0043066(negative regulation of apoptotic process);GO:0050731(positive regulation of peptidyl-tyrosine phosphorylation);GO:0035722(interleukin-12-mediated signaling pathway);GO:0007165(signal transduction);GO:0043408(regulation of MAPK cascade);GO:0016477(cell migration);GO:0048010(vascular endothelial growth factor receptor signaling pathway);GO:0007346(regulation of mitotic cell cycle);GO:0019901(protein kinase binding);GO:0018105(peptidyl-serine phosphorylation);GO:0031295(T cell costimulation);GO:2001238(positive regulation of extrinsic apoptotic signaling pathway);GO:0050690(regulation of defense response to virus by virus);GO:0031098(stress-activated protein kinase signaling cascade);GO:0023014(signal transduction by protein phosphorylation);GO:0030036(actin cytoskeleton organization);GO:0030296(protein tyrosine kinase activator activity);GO:0006469(negative regulation of protein kinase activity);GO:0046777(protein autophosphorylation);GO:0031267(small GTPase binding);GO:0048365(Rac GTPase binding);GO:0060996(dendritic spine development);GO:0071407(cellular response to organic cyclic compound);GO:2001271(negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis);GO:2001271(negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis)","04014(Ras signaling pathway);04010(MAPK signaling pathway);04012(ErbB signaling pathway);04510(Focal adhesion);04810(Regulation of actin cytoskeleton);04660(T cell receptor signaling pathway);04360(Axon guidance);05211(Renal cell carcinoma);05211(Renal cell carcinoma)","K04410","EC:2.7.11.1","p21 (RAC1) activated kinase 2 [Source:HGNC Symbol;Acc:HGNC:8591]",{"v":38.0349092734269,"d":"38.03"},{"v":13.4089441125698,"d":"13.41"},{"v":2.83653276157459,"d":"2.84"},{"v":1.50412852704011,"d":"1.50"},{"v":0.0627388124301533,"d":"0.06"},{"v":0.554190580962826,"d":"0.55"},"up","no"]
["MSTRG.841","LINC00623","MSTRG.841.1;ENST00000617702;ENST00000621058;ENST00000615424;ENST00000614062;ENST00000613486","NA","NA","NA","NA","long intergenic non-protein coding RNA 623 [Source:HGNC Symbol;Acc:HGNC:44252]",{"v":2.81541137086093,"d":"2.82"},{"v":5.51168244391556,"d":"5.51"},{"v":0.510807979144174,"d":"0.51"},{"v":-0.969147033860387,"d":"-0.97"},{"v":0.0627462862654838,"d":"0.06"},{"v":0.554190580962826,"d":"0.55"},"down","no"]
["MSTRG.10239","DERL3","ENST00000406855;ENST00000464034;ENST00000404056;ENST00000464110;ENST00000464023;ENST00000318109;ENST00000290730;ENST00000476077","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0004252(serine-type endopeptidase activity);GO:0018279(protein N-linked glycosylation via asparagine);GO:0005515(protein binding);GO:0030433(ubiquitin-dependent ERAD pathway);GO:0030176(integral component of endoplasmic reticulum membrane);GO:0030968(endoplasmic reticulum unfolded protein response);GO:1904153(negative regulation of retrograde protein transport, ER to cytosol);GO:0005785(signal recognition particle receptor complex);GO:0048500(signal recognition particle);GO:0048500(signal recognition particle)","04141(Protein processing in endoplasmic reticulum);04141(Protein processing in endoplasmic reticulum)","K13989","NA","derlin 3 [Source:HGNC Symbol;Acc:HGNC:14236]",{"v":0.279324454689146,"d":"0.28"},{"v":0.570424853530032,"d":"0.57"},{"v":0.489677918065048,"d":"0.49"},{"v":-1.0300949554393,"d":"-1.03"},{"v":0.0627730215938903,"d":"0.06"},{"v":0.554190580962826,"d":"0.55"},"down","no"]
["MSTRG.15504","FLNA","ENST00000422373;ENST00000369850;MSTRG.15504.3;ENST00000490936;ENST00000474358;ENST00000498491;ENST00000466325;ENST00000466319;ENST00000369856;ENST00000438732;ENST00000415241;ENST00000344736;ENST00000420627;ENST00000360319;ENST00000465144;ENST00000474072;ENST00000462590","GO:0051015(actin filament binding);GO:0003779(actin binding);GO:0005737(cytoplasm);GO:0003723(RNA binding);GO:0005634(nucleus);GO:0016020(membrane);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0015629(actin cytoskeleton);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0004871(signal transducer activity);GO:0005925(focal adhesion);GO:0005576(extracellular region);GO:0060271(cilium assembly);GO:0045296(cadherin binding);GO:0070062(extracellular exosome);GO:0030030(cell projection organization);GO:0005938(cell cortex);GO:0031012(extracellular matrix);GO:0043123(positive regulation of I-kappaB kinase/NF-kappaB signaling);GO:0030334(regulation of cell migration);GO:0042803(protein homodimerization activity);GO:0044325(ion channel binding);GO:0070527(platelet aggregation);GO:0002576(platelet degranulation);GO:0008134(transcription factor binding);GO:0001664(G-protein coupled receptor binding);GO:0030168(platelet activation);GO:0043433(negative regulation of sequence-specific DNA binding transcription factor activity);GO:0042993(positive regulation of transcription factor import into nucleus);GO:0005911(cell-cell junction);GO:0050821(protein stabilization);GO:0043113(receptor clustering);GO:0044319(wound healing, spreading of cells);GO:0005730(nucleolus);GO:0030018(Z disc);GO:0017048(Rho GTPase binding);GO:0019900(kinase binding);GO:1901381(positive regulation of potassium ion transmembrane transport);GO:0015459(potassium channel regulator activity);GO:0051020(GTPase binding);GO:0048365(Rac GTPase binding);GO:0031267(small GTPase binding);GO:0043066(negative regulation of apoptotic process);GO:0051220(cytoplasmic sequestering of protein);GO:0072659(protein localization to plasma membrane);GO:0031532(actin cytoskeleton reorganization);GO:0034394(protein localization to cell surface);GO:0031941(filamentous actin);GO:0017160(Ral GTPase binding);GO:0034988(Fc-gamma receptor I complex binding);GO:0007195(adenylate cyclase-inhibiting dopamine receptor signaling pathway);GO:0016479(negative regulation of transcription from RNA polymerase I promoter);GO:0034329(cell junction assembly);GO:0042177(negative regulation of protein catabolic process);GO:0045184(establishment of protein localization);GO:0051764(actin crosslink formation);GO:0071526(semaphorin-plexin signaling pathway);GO:0090307(mitotic spindle assembly);GO:1900026(positive regulation of substrate adhesion-dependent cell spreading);GO:1905000(regulation of membrane repolarization during atrial cardiac muscle cell action potential);GO:1905031(regulation of membrane repolarization during cardiac muscle cell action potential);GO:2001046(positive regulation of integrin-mediated signaling pathway);GO:0031523(Myb complex);GO:0031852(mu-type opioid receptor binding);GO:0032403(protein complex binding);GO:0046332(SMAD binding);GO:0021943(formation of radial glial scaffolds);GO:0021987(cerebral cortex development);GO:0042789(mRNA transcription from RNA polymerase II promoter);GO:2000179(positive regulation of neural precursor cell proliferation);GO:2001224(positive regulation of neuron migration);GO:0005884(actin filament);GO:0030863(cortical cytoskeleton);GO:0043025(neuronal cell body);GO:0043198(dendritic shaft);GO:0043234(protein complex);GO:0048471(perinuclear region of cytoplasm);GO:0097440(apical dendrite);GO:0097440(apical dendrite)","04010(MAPK signaling pathway);04510(Focal adhesion);05205(Proteoglycans in cancer);05132(Salmonella infection);05132(Salmonella infection)","K04437","NA","filamin A [Source:HGNC Symbol;Acc:HGNC:3754]",{"v":143.323355983758,"d":"143.32"},{"v":50.5677215651558,"d":"50.57"},{"v":2.83428542057383,"d":"2.83"},{"v":1.50298504905067,"d":"1.50"},{"v":0.0628015848227916,"d":"0.06"},{"v":0.554190580962826,"d":"0.55"},"up","no"]
["MSTRG.14930","MEGF9","ENST00000373930","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0008150(biological_process);GO:0005575(cellular_component);GO:0005604(basement membrane)","NA","NA","NA","multiple EGF like domains 9 [Source:HGNC Symbol;Acc:HGNC:3234]",{"v":53.810158,"d":"53.81"},{"v":18.987877,"d":"18.99"},{"v":2.83392177019053,"d":"2.83"},{"v":1.50279993351496,"d":"1.50"},{"v":0.0628785918484759,"d":"0.06"},{"v":0.554247030007479,"d":"0.55"},"up","no"]
["ENSG00000159958","TNFRSF13C","ENST00000291232","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0002376(immune system process);GO:0002250(adaptive immune response);GO:0005886(plasma membrane);GO:0033209(tumor necrosis factor-mediated signaling pathway);GO:0001782(B cell homeostasis);GO:0002636(positive regulation of germinal center formation);GO:0030890(positive regulation of B cell proliferation);GO:0031295(T cell costimulation);GO:0031296(B cell costimulation);GO:0042102(positive regulation of T cell proliferation);GO:0045078(positive regulation of interferon-gamma biosynthetic process);GO:0050776(regulation of immune response);GO:0009897(external side of plasma membrane)","04064(NF-kappa B signaling pathway);04060(Cytokine-cytokine receptor interaction);04672(Intestinal immune network for IgA production);05340(Primary immunodeficiency);05166(HTLV-I infection)","K05151","NA","TNF receptor superfamily member 13C [Source:HGNC Symbol;Acc:HGNC:17755]",{"v":2.815409,"d":"2.82"},{"v":0.983195,"d":"0.98"},{"v":2.86353063227539,"d":"2.86"},{"v":1.51779503660267,"d":"1.52"},{"v":0.0629034345603942,"d":"0.06"},{"v":0.554247030007479,"d":"0.55"},"up","no"]
["MSTRG.9960","RPL13AP7","ENST00000425147","NA","NA","NA","NA","ribosomal protein L13a pseudogene 7 [Source:HGNC Symbol;Acc:HGNC:23755]",{"v":2.431081,"d":"2.43"},{"v":4.900743,"d":"4.90"},{"v":0.496063760127801,"d":"0.50"},{"v":-1.01140252970197,"d":"-1.01"},{"v":0.0630318083464659,"d":"0.06"},{"v":0.554482502080015,"d":"0.55"},"down","no"]
["ENSG00000148158","SNX30","ENST00000374232;ENST00000604751;ENST00000416585","GO:0006810(transport);GO:0005737(cytoplasm);GO:0015031(protein transport);GO:0005515(protein binding);GO:0035091(phosphatidylinositol binding);GO:0005768(endosome);GO:0019898(extrinsic component of membrane);GO:0006897(endocytosis);GO:0016050(vesicle organization);GO:0016050(vesicle organization)","NA","NA","NA","sorting nexin family member 30 [Source:HGNC Symbol;Acc:HGNC:23685]",{"v":3.2934281447573,"d":"3.29"},{"v":1.15844303403006,"d":"1.16"},{"v":2.84297807316423,"d":"2.84"},{"v":1.50740297208641,"d":"1.51"},{"v":0.0630773106341091,"d":"0.06"},{"v":0.554482502080015,"d":"0.55"},"up","no"]
["ENSG00000113924","HGD","ENST00000283871;ENST00000492108;ENST00000480862;ENST00000466528;ENST00000470321;ENST00000494453;ENST00000475447","GO:0046872(metal ion binding);GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0005515(protein binding);GO:0051213(dioxygenase activity);GO:0006559(L-phenylalanine catabolic process);GO:0042802(identical protein binding);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0004411(homogentisate 1,2-dioxygenase activity);GO:0006570(tyrosine metabolic process);GO:0006572(tyrosine catabolic process);GO:0006520(cellular amino acid metabolic process);GO:0006520(cellular amino acid metabolic process)","00350(Tyrosine metabolism);00350(Tyrosine metabolism)","K00451","EC:1.13.11.5","homogentisate 1,2-dioxygenase [Source:HGNC Symbol;Acc:HGNC:4892]",{"v":0.888649055983909,"d":"0.89"},{"v":1.78553045558163,"d":"1.79"},{"v":0.49769470646998,"d":"0.50"},{"v":-1.00666705243767,"d":"-1.01"},{"v":0.0630866874941255,"d":"0.06"},{"v":0.554482502080015,"d":"0.55"},"down","no"]
["MSTRG.14677","SMARCA2","MSTRG.14677.12;MSTRG.14677.17;ENST00000637806;ENST00000635688;ENST00000349721;ENST00000636969;ENST00000639760;ENST00000636916;ENST00000423555;ENST00000636221;ENST00000634760;ENST00000636903;ENST00000634343;ENST00000635030;ENST00000637371;ENST00000302401;ENST00000634403;ENST00000635133;ENST00000635392;ENST00000635129;ENST00000637352;ENST00000637097;ENST00000382203;ENST00000635185;ENST00000634435;ENST00000636233;ENST00000357248;ENST00000491574;ENST00000635388;ENST00000634536;ENST00000636559;ENST00000450198;ENST00000637134;ENST00000635590;ENST00000637383;ENST00000638139;ENST00000635226;ENST00000634931;ENST00000324954;ENST00000634287;ENST00000457226;ENST00000636501;ENST00000634925;ENST00000417599;ENST00000382185;ENST00000635739","GO:0016514(SWI/SNF complex);GO:0016887(ATPase activity);GO:0006338(chromatin remodeling);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0005634(nucleus);GO:0043231(intracellular membrane-bounded organelle);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0005654(nucleoplasm);GO:0006355(regulation of transcription, DNA-templated);GO:0016787(hydrolase activity);GO:0006351(transcription, DNA-templated);GO:0004386(helicase activity);GO:0003677(DNA binding);GO:0045111(intermediate filament cytoskeleton);GO:0005515(protein binding);GO:0007399(nervous system development);GO:0045893(positive regulation of transcription, DNA-templated);GO:0042393(histone binding);GO:0016817(hydrolase activity, acting on acid anhydrides);GO:0008285(negative regulation of cell proliferation);GO:0003713(transcription coactivator activity);GO:0044212(transcription regulatory region DNA binding);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0000790(nuclear chromatin);GO:0045892(negative regulation of transcription, DNA-templated);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0071564(npBAF complex);GO:0071565(nBAF complex);GO:0001105(RNA polymerase II transcription coactivator activity);GO:0030308(negative regulation of cell growth);GO:0008094(DNA-dependent ATPase activity);GO:0003682(chromatin binding);GO:0007286(spermatid development);GO:0007286(spermatid development)","05225(Hepatocellular carcinoma);05225(Hepatocellular carcinoma)","K11647","EC:3.6.4.-","SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 [Source:HGNC Symbol;Acc:HGNC:11098]",{"v":6.16698560197664,"d":"6.17"},{"v":2.1765751490936,"d":"2.18"},{"v":2.83334375316413,"d":"2.83"},{"v":1.50250564615645,"d":"1.50"},{"v":0.0631211459355704,"d":"0.06"},{"v":0.554482502080015,"d":"0.55"},"up","no"]
["MSTRG.10926","GPX1","ENST00000419349;ENST00000620890;MSTRG.10926.1;ENST00000419783","GO:0005737(cytoplasm);GO:0043154(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process);GO:0005829(cytosol);GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0098869(cellular oxidant detoxification);GO:0004601(peroxidase activity);GO:0004602(glutathione peroxidase activity);GO:0006979(response to oxidative stress);GO:0070062(extracellular exosome);GO:0005759(mitochondrial matrix);GO:0034599(cellular response to oxidative stress);GO:0019372(lipoxygenase pathway);GO:1902042(negative regulation of extrinsic apoptotic signaling pathway via death domain receptors);GO:0005739(mitochondrion);GO:0017124(SH3 domain binding);GO:0006195(purine nucleotide catabolic process);GO:0090201(negative regulation of release of cytochrome c from mitochondria);GO:0097413(Lewy body);GO:0042542(response to hydrogen peroxide);GO:0042744(hydrogen peroxide catabolic process);GO:0000302(response to reactive oxygen species);GO:0001659(temperature homeostasis);GO:0001885(endothelial cell development);GO:0002862(negative regulation of inflammatory response to antigenic stimulus);GO:0006629(lipid metabolic process);GO:0006641(triglyceride metabolic process);GO:0006749(glutathione metabolic process);GO:0006915(apoptotic process);GO:0007605(sensory perception of sound);GO:0008283(cell proliferation);GO:0008631(intrinsic apoptotic signaling pathway in response to oxidative stress);GO:0009410(response to xenobiotic stimulus);GO:0009609(response to symbiotic bacterium);GO:0009611(response to wounding);GO:0009636(response to toxic substance);GO:0009650(UV protection);GO:0010269(response to selenium ion);GO:0010332(response to gamma radiation);GO:0014902(myotube differentiation);GO:0018158(protein oxidation);GO:0033194(response to hydroperoxide);GO:0033599(regulation of mammary gland epithelial cell proliferation);GO:0040029(regulation of gene expression, epigenetic);GO:0042311(vasodilation);GO:0043066(negative regulation of apoptotic process);GO:0043403(skeletal muscle tissue regeneration);GO:0043523(regulation of neuron apoptotic process);GO:0043534(blood vessel endothelial cell migration);GO:0045444(fat cell differentiation);GO:0045454(cell redox homeostasis);GO:0048741(skeletal muscle fiber development);GO:0051450(myoblast proliferation);GO:0051702(interaction with symbiont);GO:0051897(positive regulation of protein kinase B signaling);GO:0060047(heart contraction);GO:0060055(angiogenesis involved in wound healing);GO:0061136(regulation of proteasomal protein catabolic process);GO:1902176(negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway);GO:1902905(positive regulation of supramolecular fiber organization);GO:1902905(positive regulation of supramolecular fiber organization)","00590(Arachidonic acid metabolism);00480(Glutathione metabolism);04918(Thyroid hormone synthesis);05014(Amyotrophic lateral sclerosis (ALS));05016(Huntington's disease);05016(Huntington's disease)","K00432","EC:1.11.1.9","glutathione peroxidase 1 [Source:HGNC Symbol;Acc:HGNC:4553]",{"v":200.647437917713,"d":"200.65"},{"v":390.858676220363,"d":"390.86"},{"v":0.51335034917989,"d":"0.51"},{"v":-0.961984328494642,"d":"-0.96"},{"v":0.0632909985177754,"d":"0.06"},{"v":0.555522031983714,"d":"0.56"},"down","no"]
["MSTRG.14064","TRBV6-4","ENST00000390360","NA","NA","NA","NA","T-cell receptor beta variable 6-4 [Source:HGNC Symbol;Acc:HGNC:12229]",{"v":2.169994,"d":"2.17"},{"v":4.544852,"d":"4.54"},{"v":0.477461972359056,"d":"0.48"},{"v":-1.06654226116036,"d":"-1.07"},{"v":0.0633529014098939,"d":"0.06"},{"v":0.555522031983714,"d":"0.56"},"down","no"]
["MSTRG.5572","MMP25","ENST00000336577;ENST00000575441;ENST00000612971;ENST00000570755","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0016787(hydrolase activity);GO:0005886(plasma membrane);GO:0008233(peptidase activity);GO:0006508(proteolysis);GO:0005576(extracellular region);GO:0006954(inflammatory response);GO:0005578(proteinaceous extracellular matrix);GO:0004222(metalloendopeptidase activity);GO:0008237(metallopeptidase activity);GO:0031012(extracellular matrix);GO:0031225(anchored component of membrane);GO:0043312(neutrophil degranulation);GO:0035579(specific granule membrane);GO:0060022(hard palate development);GO:0060022(hard palate development)","NA","NA","NA","matrix metallopeptidase 25 [Source:HGNC Symbol;Acc:HGNC:14246]",{"v":29.9280410991275,"d":"29.93"},{"v":10.5694246442075,"d":"10.57"},{"v":2.83156766868378,"d":"2.83"},{"v":1.50160100770223,"d":"1.50"},{"v":0.0634786808416585,"d":"0.06"},{"v":0.555522031983714,"d":"0.56"},"up","no"]
["ENSG00000204580","DDR1","ENST00000431373;ENST00000418800;ENST00000376568;ENST00000514534;ENST00000454612;ENST00000484556;ENST00000324771;ENST00000504152;ENST00000508312;ENST00000504679;ENST00000485023;ENST00000507533;ENST00000502955;ENST00000506573;ENST00000508472;ENST00000376567","GO:0005887(integral component of plasma membrane);GO:0038062(protein tyrosine kinase collagen receptor activity);GO:0038063(collagen-activated tyrosine kinase receptor signaling pathway);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0004713(protein tyrosine kinase activity);GO:0007169(transmembrane receptor protein tyrosine kinase signaling pathway);GO:0018108(peptidyl-tyrosine phosphorylation);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0004714(transmembrane receptor protein tyrosine kinase activity);GO:0005615(extracellular space);GO:0070062(extracellular exosome);GO:0007565(female pregnancy);GO:0007155(cell adhesion);GO:0046777(protein autophosphorylation);GO:0030198(extracellular matrix organization);GO:0044319(wound healing, spreading of cells);GO:0043235(receptor complex);GO:0005518(collagen binding);GO:0038083(peptidyl-tyrosine autophosphorylation);GO:0007595(lactation);GO:0010715(regulation of extracellular matrix disassembly);GO:0014909(smooth muscle cell migration);GO:0061302(smooth muscle cell-matrix adhesion);GO:0001558(regulation of cell growth);GO:0001952(regulation of cell-matrix adhesion);GO:0007566(embryo implantation);GO:0008285(negative regulation of cell proliferation);GO:0043583(ear development);GO:0060444(branching involved in mammary gland duct morphogenesis);GO:0060749(mammary gland alveolus development);GO:0061564(axon development);GO:1990138(neuron projection extension);GO:1990138(neuron projection extension)","NA","NA","NA","discoidin domain receptor tyrosine kinase 1 [Source:HGNC Symbol;Acc:HGNC:2730]",{"v":0.419430958561719,"d":"0.42"},{"v":0.141965065665424,"d":"0.14"},{"v":2.95446599200829,"d":"2.95"},{"v":1.5628973925681,"d":"1.56"},{"v":0.0635240524554216,"d":"0.06"},{"v":0.555522031983714,"d":"0.56"},"up","no"]
["MSTRG.1539","TAF3","ENST00000344293","GO:0043433(negative regulation of sequence-specific DNA binding transcription factor activity);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0005654(nucleoplasm);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0031965(nuclear membrane);GO:0005515(protein binding);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0006366(transcription from RNA polymerase II promoter);GO:0006368(transcription elongation from RNA polymerase II promoter);GO:0006367(transcription initiation from RNA polymerase II promoter);GO:1901796(regulation of signal transduction by p53 class mediator);GO:0005669(transcription factor TFIID complex);GO:0051457(maintenance of protein location in nucleus);GO:0002039(p53 binding)","03022(Basal transcription factors);05168(Herpes simplex infection)","K14650","NA","TATA-box binding protein associated factor 3 [Source:HGNC Symbol;Acc:HGNC:17303]",{"v":3.277639,"d":"3.28"},{"v":1.150177,"d":"1.15"},{"v":2.84968226629467,"d":"2.85"},{"v":1.51080107071773,"d":"1.51"},{"v":0.0635688984341413,"d":"0.06"},{"v":0.555522031983714,"d":"0.56"},"up","no"]
["MSTRG.8787","MXD1;SNRNP27","ENST00000264444;ENST00000540449;ENST00000244227;ENST00000450162;ENST00000435990;ENST00000409442;ENST00000409116;ENST00000410000;ENST00000465446;ENST00000488986;ENST00000487029","GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0046983(protein dimerization activity);GO:0005739(mitochondrion);GO:0005634(nucleus);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:0001078(transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0007275(multicellular organism development);GO:0000790(nuclear chromatin);GO:0003714(transcription corepressor activity);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0008283(cell proliferation);GO:0003712(transcription cofactor activity);GO:0006397(mRNA processing);GO:0008380(RNA splicing);GO:0003676(nucleic acid binding);GO:0008150(biological_process);GO:0005575(cellular_component);GO:0000398(mRNA splicing, via spliceosome);GO:0000398(mRNA splicing, via spliceosome)","03040(Spliceosome);03040(Spliceosome)","K12846","NA","MAX dimerization protein 1 [Source:HGNC Symbol;Acc:HGNC:6761];small nuclear ribonucleoprotein U4/U6.U5 subunit 27 [Source:HGNC Symbol;Acc:HGNC:30240]",{"v":21.3201638161879,"d":"21.32"},{"v":41.4939420129932,"d":"41.49"},{"v":0.513813891423278,"d":"0.51"},{"v":-0.960682199556072,"d":"-0.96"},{"v":0.0636221643712804,"d":"0.06"},{"v":0.555522031983714,"d":"0.56"},"down","no"]
["ENSG00000111912","NCOA7","ENST00000368357;ENST00000392477;ENST00000229634;ENST00000453302;ENST00000417494;ENST00000444128;ENST00000438495;ENST00000428318;ENST00000487635;ENST00000433571","GO:0005634(nucleus);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0005515(protein binding);GO:0030374(ligand-dependent nuclear receptor transcription coactivator activity);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0005622(intracellular);GO:0035257(nuclear hormone receptor binding);GO:1900408(negative regulation of cellular response to oxidative stress);GO:1902083(negative regulation of peptidyl-cysteine S-nitrosylation);GO:1903204(negative regulation of oxidative stress-induced neuron death);GO:1903204(negative regulation of oxidative stress-induced neuron death)","NA","NA","NA","nuclear receptor coactivator 7 [Source:HGNC Symbol;Acc:HGNC:21081]",{"v":3.44813393746803,"d":"3.45"},{"v":1.21420723299233,"d":"1.21"},{"v":2.83982325568127,"d":"2.84"},{"v":1.50580114237541,"d":"1.51"},{"v":0.0636623546847129,"d":"0.06"},{"v":0.555522031983714,"d":"0.56"},"up","no"]
["ENSG00000197217","ENTPD4","ENST00000358689;ENST00000523958;ENST00000417069;ENST00000520936;ENST00000518471;ENST00000521321;ENST00000522913;ENST00000522255;ENST00000519839;ENST00000518718","GO:0016787(hydrolase activity);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005794(Golgi apparatus);GO:0000139(Golgi membrane);GO:0031410(cytoplasmic vesicle);GO:0000421(autophagosome membrane);GO:0030173(integral component of Golgi membrane);GO:0017110(nucleoside-diphosphatase activity);GO:0045134(uridine-diphosphatase activity);GO:0034656(nucleobase-containing small molecule catabolic process);GO:0017111(nucleoside-triphosphatase activity);GO:0006256(UDP catabolic process);GO:0097637(integral component of autophagosome membrane);GO:0097637(integral component of autophagosome membrane)","00230(Purine metabolism);00240(Pyrimidine metabolism);04142(Lysosome);04142(Lysosome)","K12305","EC:3.6.1.6","ectonucleoside triphosphate diphosphohydrolase 4 [Source:HGNC Symbol;Acc:HGNC:14573]",{"v":5.43541252533975,"d":"5.44"},{"v":1.91467052519819,"d":"1.91"},{"v":2.838823940624,"d":"2.84"},{"v":1.50529337816944,"d":"1.51"},{"v":0.0637092786965181,"d":"0.06"},{"v":0.555522031983714,"d":"0.56"},"up","no"]
["MSTRG.9471","AC009950.1","ENST00000454058;ENST00000625295;ENST00000600787;ENST00000628587;ENST00000595586;ENST00000609120","NA","NA","NA","NA",null,{"v":0.665804332619175,"d":"0.67"},{"v":0.223884943224424,"d":"0.22"},{"v":2.97386828712178,"d":"2.97"},{"v":1.57234075171979,"d":"1.57"},{"v":0.0637454596823287,"d":"0.06"},{"v":0.555522031983714,"d":"0.56"},"up","no"]
["MSTRG.13575","ELMO1","ENST00000448602;ENST00000310758;ENST00000396040;ENST00000442504;ENST00000463390;ENST00000497024;ENST00000433246;ENST00000479447;ENST00000472359;ENST00000453399;ENST00000487336;ENST00000396045;ENST00000445322;ENST00000424212;ENST00000464262","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005886(plasma membrane);GO:0043547(positive regulation of GTPase activity);GO:0030036(actin cytoskeleton organization);GO:0005515(protein binding);GO:0006915(apoptotic process);GO:0016477(cell migration);GO:0038096(Fc-gamma receptor signaling pathway involved in phagocytosis);GO:0006909(phagocytosis);GO:0005829(cytosol);GO:0017124(SH3 domain binding);GO:0048010(vascular endothelial growth factor receptor signaling pathway);GO:0050690(regulation of defense response to virus by virus);GO:0048870(cell motility);GO:0006911(phagocytosis, engulfment);GO:0016601(Rac protein signal transduction);GO:0005085(guanyl-nucleotide exchange factor activity);GO:0032045(guanyl-nucleotide exchange factor complex);GO:0030029(actin filament-based process);GO:0030029(actin filament-based process)","04062(Chemokine signaling pathway);05131(Shigellosis);05100(Bacterial invasion of epithelial cells);05100(Bacterial invasion of epithelial cells)","K12366","NA","engulfment and cell motility 1 [Source:HGNC Symbol;Acc:HGNC:16286]",{"v":5.90023324702194,"d":"5.90"},{"v":2.08139311504702,"d":"2.08"},{"v":2.8347519766292,"d":"2.83"},{"v":1.50322251374237,"d":"1.50"},{"v":0.0637788304229316,"d":"0.06"},{"v":0.555522031983714,"d":"0.56"},"up","no"]
["ENSG00000151611","MMAA","ENST00000541599;ENST00000503730;ENST00000281317;ENST00000511969","GO:0005525(GTP binding);GO:0000166(nucleotide binding);GO:0016787(hydrolase activity);GO:0003924(GTPase activity);GO:0005739(mitochondrion);GO:0005759(mitochondrial matrix);GO:0009235(cobalamin metabolic process);GO:0019626(short-chain fatty acid catabolic process);GO:0009236(cobalamin biosynthetic process);GO:0009236(cobalamin biosynthetic process)","NA","NA","NA","methylmalonic aciduria (cobalamin deficiency) cblA type [Source:HGNC Symbol;Acc:HGNC:18871]",{"v":0.474700578481178,"d":"0.47"},{"v":0.159000214927706,"d":"0.16"},{"v":2.98553419375574,"d":"2.99"},{"v":1.57798909220379,"d":"1.58"},{"v":0.0638321075197157,"d":"0.06"},{"v":0.555522031983714,"d":"0.56"},"up","no"]
["MSTRG.15400","ACSL4;KCNE5","ENST00000348502;ENST00000514500;ENST00000504383;ENST00000439581;ENST00000372101;ENST00000502391;ENST00000505075;ENST00000340800;ENST00000505855;ENST00000469796","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0003824(catalytic activity);GO:0006629(lipid metabolic process);GO:0008152(metabolic process);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0006631(fatty acid metabolic process);GO:0005739(mitochondrion);GO:0016874(ligase activity);GO:0005741(mitochondrial outer membrane);GO:0001676(long-chain fatty acid metabolic process);GO:0005777(peroxisome);GO:0005778(peroxisomal membrane);GO:0043231(intracellular membrane-bounded organelle);GO:0070062(extracellular exosome);GO:0035338(long-chain fatty-acyl-CoA biosynthetic process);GO:0031090(organelle membrane);GO:0005811(lipid particle);GO:0004467(long-chain fatty acid-CoA ligase activity);GO:0031957(very long-chain fatty acid-CoA ligase activity);GO:0102391(decanoate--CoA ligase activity);GO:0047676(arachidonate-CoA ligase activity);GO:0044233(ER-mitochondrion membrane contact site);GO:0006641(triglyceride metabolic process);GO:0007584(response to nutrient);GO:0015908(fatty acid transport);GO:0030182(neuron differentiation);GO:0060136(embryonic process involved in female pregnancy);GO:0060996(dendritic spine development);GO:0070672(response to interleukin-15);GO:0031966(mitochondrial membrane);GO:0043025(neuronal cell body);GO:0008016(regulation of heart contraction);GO:0060307(regulation of ventricular cardiac muscle cell membrane repolarization);GO:0006811(ion transport);GO:0005249(voltage-gated potassium channel activity);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0044325(ion channel binding);GO:0060048(cardiac muscle contraction);GO:0060306(regulation of membrane repolarization);GO:0008076(voltage-gated potassium channel complex);GO:0086091(regulation of heart rate by cardiac conduction);GO:1901381(positive regulation of potassium ion transmembrane transport);GO:0015459(potassium channel regulator activity);GO:0060372(regulation of atrial cardiac muscle cell membrane repolarization);GO:0086008(voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization);GO:0071435(potassium ion export);GO:0071805(potassium ion transmembrane transport);GO:0086005(ventricular cardiac muscle cell action potential);GO:1901379(regulation of potassium ion transmembrane transport);GO:0086014(atrial cardiac muscle cell action potential);GO:1901380(negative regulation of potassium ion transmembrane transport);GO:2001257(regulation of cation channel activity);GO:0086013(membrane repolarization during cardiac muscle cell action potential);GO:0043025(neuronal cell body)","00061(Fatty acid biosynthesis);00071(Fatty acid degradation);04146(Peroxisome);04216(Ferroptosis);04920(Adipocytokine signaling pathway);03320(PPAR signaling pathway);03320(PPAR signaling pathway)","K01897","EC:6.2.1.3","acyl-CoA synthetase long chain family member 4 [Source:HGNC Symbol;Acc:HGNC:3571];potassium voltage-gated channel subfamily E regulatory subunit 5 [Source:HGNC Symbol;Acc:HGNC:6241]",{"v":10.6169577864277,"d":"10.62"},{"v":3.74932688271447,"d":"3.75"},{"v":2.83169702683836,"d":"2.83"},{"v":1.5016669146934,"d":"1.50"},{"v":0.0638495825137801,"d":"0.06"},{"v":0.555522031983714,"d":"0.56"},"up","no"]
["MSTRG.4285","PSME2","ENST00000559453;ENST00000216802;ENST00000558931;ENST00000560788;ENST00000559042;ENST00000560592;ENST00000559613;ENST00000615264;ENST00000559359;ENST00000559056;ENST00000558273;ENST00000559493;ENST00000561103;ENST00000630027;ENST00000560410;ENST00000560370;ENST00000559005","GO:0008537(proteasome activator complex);GO:0016020(membrane);GO:0005515(protein binding);GO:0000502(proteasome complex);GO:0038095(Fc-epsilon receptor signaling pathway);GO:0042802(identical protein binding);GO:0005737(cytoplasm);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0000165(MAPK cascade);GO:0000209(protein polyubiquitination);GO:0002223(stimulatory C-type lectin receptor signaling pathway);GO:0002479(antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent);GO:0006521(regulation of cellular amino acid metabolic process);GO:0010972(negative regulation of G2/M transition of mitotic cell cycle);GO:0016579(protein deubiquitination);GO:0031145(anaphase-promoting complex-dependent catabolic process);GO:0031146(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process);GO:0033209(tumor necrosis factor-mediated signaling pathway);GO:0038061(NIK/NF-kappaB signaling);GO:0043161(proteasome-mediated ubiquitin-dependent protein catabolic process);GO:0043488(regulation of mRNA stability);GO:0043687(post-translational protein modification);GO:0050852(T cell receptor signaling pathway);GO:0051437(positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition);GO:0055085(transmembrane transport);GO:0060071(Wnt signaling pathway, planar cell polarity pathway);GO:0061418(regulation of transcription from RNA polymerase II promoter in response to hypoxia);GO:0090090(negative regulation of canonical Wnt signaling pathway);GO:0090263(positive regulation of canonical Wnt signaling pathway);GO:1902036(regulation of hematopoietic stem cell differentiation);GO:0035722(interleukin-12-mediated signaling pathway);GO:0051436(negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle);GO:2000045(regulation of G1/S transition of mitotic cell cycle);GO:0061133(endopeptidase activator activity);GO:0010950(positive regulation of endopeptidase activity);GO:0061136(regulation of proteasomal protein catabolic process);GO:0061136(regulation of proteasomal protein catabolic process)","03050(Proteasome);04612(Antigen processing and presentation);04612(Antigen processing and presentation)","K06697","NA","proteasome activator subunit 2 [Source:HGNC Symbol;Acc:HGNC:9569]",{"v":10.3655810435511,"d":"10.37"},{"v":20.198722647962,"d":"20.20"},{"v":0.513180027480449,"d":"0.51"},{"v":-0.962463071801186,"d":"-0.96"},{"v":0.0638613547488382,"d":"0.06"},{"v":0.555522031983714,"d":"0.56"},"down","no"]
["ENSG00000175066","GK5","ENST00000480757;ENST00000486459;ENST00000460515;ENST00000489085;ENST00000392993;ENST00000463349;ENST00000460544;ENST00000460630;ENST00000487672;ENST00000492097","GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0016773(phosphotransferase activity, alcohol group as acceptor);GO:0005975(carbohydrate metabolic process);GO:0005739(mitochondrion);GO:0004370(glycerol kinase activity);GO:0006071(glycerol metabolic process);GO:0019563(glycerol catabolic process);GO:0006641(triglyceride metabolic process);GO:0046167(glycerol-3-phosphate biosynthetic process);GO:0046167(glycerol-3-phosphate biosynthetic process)","NA","NA","NA","glycerol kinase 5 (putative) [Source:HGNC Symbol;Acc:HGNC:28635]",{"v":0.730481558315512,"d":"0.73"},{"v":0.253531258183912,"d":"0.25"},{"v":2.88122878239187,"d":"2.88"},{"v":1.52668422145495,"d":"1.53"},{"v":0.0641222066232627,"d":"0.06"},{"v":0.557373641853256,"d":"0.56"},"up","no"]
["ENSG00000196092","PAX5","ENST00000358127;ENST00000523493;ENST00000377852;ENST00000377853;ENST00000520083;ENST00000414447;ENST00000377840","GO:0005634(nucleus);GO:0043231(intracellular membrane-bounded organelle);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0001650(fibrillar center);GO:0005515(protein binding);GO:0007275(multicellular organism development);GO:0007399(nervous system development);GO:0030154(cell differentiation);GO:0007283(spermatogenesis);GO:0006366(transcription from RNA polymerase II promoter);GO:0009887(animal organ morphogenesis);GO:0006959(humoral immune response);GO:0050855(regulation of B cell receptor signaling pathway);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:0001077(transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0007568(aging);GO:0021670(lateral ventricle development);GO:0021987(cerebral cortex development);GO:0030534(adult behavior);GO:0035914(skeletal muscle cell differentiation);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0048701(embryonic cranial skeleton morphogenesis);GO:0051573(negative regulation of histone H3-K9 methylation);GO:0051573(negative regulation of histone H3-K9 methylation)","05202(Transcriptional misregulation in cancers);05202(Transcriptional misregulation in cancers)","K09383","NA","paired box 5 [Source:HGNC Symbol;Acc:HGNC:8619]",{"v":3.64675476288439,"d":"3.65"},{"v":1.28495194139076,"d":"1.28"},{"v":2.83804759183238,"d":"2.84"},{"v":1.50489878246572,"d":"1.50"},{"v":0.0642366769705399,"d":"0.06"},{"v":0.557951031906417,"d":"0.56"},"up","no"]
["MSTRG.2044","GLRX3","ENST00000331244;ENST00000368644;ENST00000481034;ENST00000486974;ENST00000619341;ENST00000496195","GO:0003723(RNA binding);GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0005829(cytosol);GO:0045454(cell redox homeostasis);GO:0055114(oxidation-reduction process);GO:0005515(protein binding);GO:0051536(iron-sulfur cluster binding);GO:0009055(electron carrier activity);GO:0015035(protein disulfide oxidoreductase activity);GO:0070062(extracellular exosome);GO:0005938(cell cortex);GO:0030018(Z disc);GO:0002026(regulation of the force of heart contraction);GO:0010614(negative regulation of cardiac muscle hypertrophy);GO:0044571([2Fe-2S] cluster assembly);GO:0097428(protein maturation by iron-sulfur cluster transfer);GO:0005080(protein kinase C binding);GO:0005634(nucleus);GO:0030425(dendrite);GO:0030425(dendrite)","NA","NA","NA","glutaredoxin 3 [Source:HGNC Symbol;Acc:HGNC:15987]",{"v":1.98276166479799,"d":"1.98"},{"v":3.87057899632708,"d":"3.87"},{"v":0.512264874758918,"d":"0.51"},{"v":-0.965038123158197,"d":"-0.97"},{"v":0.0646244548980305,"d":"0.06"},{"v":0.560899697108242,"d":"0.56"},"down","no"]
["MSTRG.10245","MIF;SLC2A11;AP000350.4","ENST00000215754;ENST00000461809;ENST00000345044;ENST00000405340;ENST00000436643;ENST00000492516;ENST00000486907;ENST00000405286;ENST00000611880;ENST00000473357;ENST00000433835;ENST00000491948;ENST00000465752;ENST00000473740;ENST00000498385;ENST00000255830;ENST00000489322","GO:0010629(negative regulation of gene expression);GO:0070374(positive regulation of ERK1 and ERK2 cascade);GO:0048146(positive regulation of fibroblast proliferation);GO:0005737(cytoplasm);GO:0016853(isomerase activity);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0005125(cytokine activity);GO:0005615(extracellular space);GO:0002376(immune system process);GO:0045087(innate immune response);GO:0006954(inflammatory response);GO:0050900(leukocyte migration);GO:0050918(positive chemotaxis);GO:0070062(extracellular exosome);GO:0008283(cell proliferation);GO:0043312(neutrophil degranulation);GO:0050178(phenylpyruvate tautomerase activity);GO:0001934(positive regulation of protein phosphorylation);GO:0002906(negative regulation of mature B cell apoptotic process);GO:0007569(cell aging);GO:0030330(DNA damage response, signal transduction by p53 class mediator);GO:0031666(positive regulation of lipopolysaccharide-mediated signaling pathway);GO:0032269(negative regulation of cellular protein metabolic process);GO:0033033(negative regulation of myeloid cell apoptotic process);GO:0033138(positive regulation of peptidyl-serine phosphorylation);GO:0042127(regulation of cell proliferation);GO:0043066(negative regulation of apoptotic process);GO:0043406(positive regulation of MAP kinase activity);GO:0043518(negative regulation of DNA damage response, signal transduction by p53 class mediator);GO:0050731(positive regulation of peptidyl-tyrosine phosphorylation);GO:0061078(positive regulation of prostaglandin secretion involved in immune response);GO:0061081(positive regulation of myeloid leukocyte cytokine production involved in immune response);GO:0090238(positive regulation of arachidonic acid secretion);GO:2000343(positive regulation of chemokine (C-X-C motif) ligand 2 production);GO:0043209(myelin sheath);GO:0009986(cell surface);GO:0035722(interleukin-12-mediated signaling pathway);GO:0034774(secretory granule lumen);GO:1904813(ficolin-1-rich granule lumen);GO:0031982(vesicle);GO:0042327(positive regulation of phosphorylation);GO:0005102(receptor binding);GO:0001516(prostaglandin biosynthetic process);GO:1902166(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator);GO:0007166(cell surface receptor signaling pathway);GO:0042056(chemoattractant activity);GO:0050715(positive regulation of cytokine secretion);GO:0030890(positive regulation of B cell proliferation);GO:0043030(regulation of macrophage activation);GO:0090344(negative regulation of cell aging);GO:0070207(protein homotrimerization);GO:0004167(dopachrome isomerase activity);GO:0005126(cytokine receptor binding);GO:0010739(positive regulation of protein kinase A signaling);GO:0019752(carboxylic acid metabolic process);GO:0071157(negative regulation of cell cycle arrest);GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005215(transporter activity);GO:0055085(transmembrane transport);GO:0005634(nucleus);GO:0005886(plasma membrane);GO:0030054(cell junction);GO:0022857(transmembrane transporter activity);GO:0022891(substrate-specific transmembrane transporter activity);GO:0008643(carbohydrate transport);GO:0008645(hexose transport);GO:0051119(sugar transmembrane transporter activity);GO:0034219(carbohydrate transmembrane transport);GO:0034219(carbohydrate transmembrane transport)","00350(Tyrosine metabolism);00360(Phenylalanine metabolism);00360(Phenylalanine metabolism)","K07253","EC:5.3.2.1","macrophage migration inhibitory factor (glycosylation-inhibiting factor) [Source:HGNC Symbol;Acc:HGNC:7097];solute carrier family 2 member 11 [Source:HGNC Symbol;Acc:HGNC:14239]",{"v":3.18751571327133,"d":"3.19"},{"v":6.19239857685769,"d":"6.19"},{"v":0.514746535402898,"d":"0.51"},{"v":-0.958065880323916,"d":"-0.96"},{"v":0.0646944490924755,"d":"0.06"},{"v":0.561087854601134,"d":"0.56"},"down","no"]
["ENSG00000105429","MEGF8","ENST00000378073;ENST00000593647;ENST00000599787;ENST00000334370","GO:0005634(nucleus);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005509(calcium ion binding);GO:0005515(protein binding);GO:0070062(extracellular exosome);GO:0030509(BMP signaling pathway);GO:0035108(limb morphogenesis);GO:0048842(positive regulation of axon extension involved in axon guidance);GO:0010468(regulation of gene expression);GO:0048704(embryonic skeletal system morphogenesis);GO:0097155(fasciculation of sensory neuron axon);GO:0030326(embryonic limb morphogenesis);GO:0097094(craniofacial suture morphogenesis);GO:0003143(embryonic heart tube morphogenesis);GO:0042074(cell migration involved in gastrulation);GO:0055113(epiboly involved in gastrulation with mouth forming second);GO:0060971(embryonic heart tube left/right pattern formation);GO:0060972(left/right pattern formation);GO:0061371(determination of heart left/right asymmetry);GO:0071907(determination of digestive tract left/right asymmetry);GO:0007368(determination of left/right symmetry);GO:0060976(coronary vasculature development);GO:0060976(coronary vasculature development)","NA","NA","NA","multiple EGF like domains 8 [Source:HGNC Symbol;Acc:HGNC:3233]",{"v":0.507441625835385,"d":"0.51"},{"v":0.177140313753078,"d":"0.18"},{"v":2.86463095319299,"d":"2.86"},{"v":1.51834929036351,"d":"1.52"},{"v":0.0648138080824763,"d":"0.06"},{"v":0.561342556194585,"d":"0.56"},"up","no"]
["MSTRG.12126","FAM169A","ENST00000389156;ENST00000510609;ENST00000514200","GO:0005634(nucleus);GO:0016020(membrane);GO:0005637(nuclear inner membrane);GO:0005635(nuclear envelope);GO:0005635(nuclear envelope)","NA","NA","NA","family with sequence similarity 169 member A [Source:HGNC Symbol;Acc:HGNC:29138]",{"v":0.390939318367347,"d":"0.39"},{"v":0.772551869970845,"d":"0.77"},{"v":0.506036336928549,"d":"0.51"},{"v":-0.982687110710066,"d":"-0.98"},{"v":0.0648445181222289,"d":"0.06"},{"v":0.561342556194585,"d":"0.56"},"down","no"]
["MSTRG.11272","SERP1","ENST00000491660;ENST00000239944;ENST00000484608;ENST00000490945","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0015031(protein transport);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005515(protein binding);GO:0005829(cytosol);GO:0006486(protein glycosylation);GO:0006950(response to stress);GO:0006464(cellular protein modification process);GO:0036498(IRE1-mediated unfolded protein response);GO:0005881(cytoplasmic microtubule);GO:0005840(ribosome);GO:0030968(endoplasmic reticulum unfolded protein response);GO:0001501(skeletal system development);GO:0006006(glucose metabolic process);GO:0007009(plasma membrane organization);GO:0009791(post-embryonic development);GO:0010259(multicellular organism aging);GO:0032024(positive regulation of insulin secretion);GO:0045727(positive regulation of translation);GO:0046622(positive regulation of organ growth);GO:0048644(muscle organ morphogenesis);GO:0060124(positive regulation of growth hormone secretion);GO:0060124(positive regulation of growth hormone secretion)","NA","NA","NA","stress associated endoplasmic reticulum protein 1 [Source:HGNC Symbol;Acc:HGNC:10759]",{"v":11.9184486711328,"d":"11.92"},{"v":23.1110512599617,"d":"23.11"},{"v":0.515703441486484,"d":"0.52"},{"v":-0.955386421661814,"d":"-0.96"},{"v":0.0648688289342232,"d":"0.06"},{"v":0.561342556194585,"d":"0.56"},"down","no"]
["ENSG00000047578","KIAA0556","ENST00000261588;ENST00000573850;ENST00000618117;ENST00000568622;ENST00000562207;ENST00000567894;ENST00000566023;ENST00000565672;ENST00000564749;ENST00000568258","GO:0005737(cytoplasm);GO:0005856(cytoskeleton);GO:0042995(cell projection);GO:0005615(extracellular space);GO:0005615(extracellular space)","NA","NA","NA","KIAA0556 [Source:HGNC Symbol;Acc:HGNC:29068]",{"v":1.9146780119583,"d":"1.91"},{"v":0.67428459229354,"d":"0.67"},{"v":2.83956957320593,"d":"2.84"},{"v":1.50567226013028,"d":"1.51"},{"v":0.0649478871875976,"d":"0.06"},{"v":0.561608200975109,"d":"0.56"},"up","no"]
["MSTRG.15362","RPS4X","MSTRG.15362.2;MSTRG.15362.1;ENST00000486733;ENST00000373626;ENST00000316084;ENST00000470671;ENST00000492695","GO:0003723(RNA binding);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0006412(translation);GO:0030529(intracellular ribonucleoprotein complex);GO:0005622(intracellular);GO:0003735(structural constituent of ribosome);GO:0005840(ribosome);GO:0022627(cytosolic small ribosomal subunit);GO:0007275(multicellular organism development);GO:0045727(positive regulation of translation);GO:0005925(focal adhesion);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0031012(extracellular matrix);GO:0019843(rRNA binding);GO:0005515(protein binding);GO:0008284(positive regulation of cell proliferation);GO:0006413(translational initiation);GO:0006364(rRNA processing);GO:0036464(cytoplasmic ribonucleoprotein granule);GO:0000184(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay);GO:0019083(viral transcription);GO:0006614(SRP-dependent cotranslational protein targeting to membrane);GO:0005844(polysome);GO:0015935(small ribosomal subunit);GO:0015935(small ribosomal subunit)","03010(Ribosome);03010(Ribosome)","K02987","NA","ribosomal protein S4, X-linked [Source:HGNC Symbol;Acc:HGNC:10424]",{"v":197.098962287175,"d":"197.10"},{"v":381.663716929058,"d":"381.66"},{"v":0.516420486267525,"d":"0.52"},{"v":-0.953381861766798,"d":"-0.95"},{"v":0.0650749227276827,"d":"0.07"},{"v":0.562118987756869,"d":"0.56"},"down","no"]
["ENSG00000136826","KLF4","ENST00000374672;ENST00000411706;ENST00000497048;ENST00000420475;ENST00000493306","GO:0050728(negative regulation of inflammatory response);GO:0010628(positive regulation of gene expression);GO:0010629(negative regulation of gene expression);GO:0034115(negative regulation of heterotypic cell-cell adhesion);GO:0090051(negative regulation of cell migration involved in sprouting angiogenesis);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0043154(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process);GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0005654(nucleoplasm);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0008270(zinc ion binding);GO:0005515(protein binding);GO:0045893(positive regulation of transcription, DNA-templated);GO:0043551(regulation of phosphatidylinositol 3-kinase activity);GO:0044212(transcription regulatory region DNA binding);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0045892(negative regulation of transcription, DNA-templated);GO:0000790(nuclear chromatin);GO:0001085(RNA polymerase II transcription factor binding);GO:0008285(negative regulation of cell proliferation);GO:0051973(positive regulation of telomerase activity);GO:0032270(positive regulation of cellular protein metabolic process);GO:0035019(somatic stem cell population maintenance);GO:0001190(transcriptional activator activity, RNA polymerase II transcription factor binding);GO:0032088(negative regulation of NF-kappaB transcription factor activity);GO:0000975(regulatory region DNA binding);GO:0000987(core promoter proximal region sequence-specific DNA binding);GO:0001010(transcription factor activity, sequence-specific DNA binding transcription factor recruiting);GO:0001047(core promoter binding);GO:0001077(transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0001221(transcription cofactor binding);GO:0003690(double-stranded DNA binding);GO:0008013(beta-catenin binding);GO:0008134(transcription factor binding);GO:0035014(phosphatidylinositol 3-kinase regulator activity);GO:0042826(histone deacetylase binding);GO:0043565(sequence-specific DNA binding);GO:1990841(promoter-specific chromatin binding);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0006366(transcription from RNA polymerase II promoter);GO:0007500(mesodermal cell fate determination);GO:0009913(epidermal cell differentiation);GO:0010033(response to organic substance);GO:0014067(negative regulation of phosphatidylinositol 3-kinase signaling);GO:0014740(negative regulation of muscle hyperplasia);GO:0019827(stem cell population maintenance);GO:0030154(cell differentiation);GO:0030336(negative regulation of cell migration);GO:0031077(post-embryonic camera-type eye development);GO:0032526(response to retinoic acid);GO:0035166(post-embryonic hemopoiesis);GO:0042127(regulation of cell proliferation);GO:0043433(negative regulation of sequence-specific DNA binding transcription factor activity);GO:0045415(negative regulation of interleukin-8 biosynthetic process);GO:0045429(positive regulation of nitric oxide biosynthetic process);GO:0045444(fat cell differentiation);GO:0045595(regulation of cell differentiation);GO:0046985(positive regulation of hemoglobin biosynthetic process);GO:0048662(negative regulation of smooth muscle cell proliferation);GO:0048679(regulation of axon regeneration);GO:0048730(epidermis morphogenesis);GO:0051247(positive regulation of protein metabolic process);GO:0051898(negative regulation of protein kinase B signaling);GO:0060070(canonical Wnt signaling pathway);GO:0060761(negative regulation of response to cytokine stimulus);GO:0070301(cellular response to hydrogen peroxide);GO:0070373(negative regulation of ERK1 and ERK2 cascade);GO:0071300(cellular response to retinoic acid);GO:0071363(cellular response to growth factor stimulus);GO:0071407(cellular response to organic cyclic compound);GO:0071409(cellular response to cycloheximide);GO:0071499(cellular response to laminar fluid shear stress);GO:1901653(cellular response to peptide);GO:1904798(positive regulation of core promoter binding);GO:1904998(negative regulation of leukocyte adhesion to arterial endothelial cell);GO:1990830(cellular response to leukemia inhibitory factor);GO:2000342(negative regulation of chemokine (C-X-C motif) ligand 2 production);GO:0000785(chromatin);GO:0005667(transcription factor complex);GO:0005719(nuclear euchromatin);GO:0005737(cytoplasm);GO:0044798(nuclear transcription factor complex);GO:0044798(nuclear transcription factor complex)","04550(Signaling pathways regulating pluripotency of stem cells);04550(Signaling pathways regulating pluripotency of stem cells)","K17846","NA","Kruppel like factor 4 [Source:HGNC Symbol;Acc:HGNC:6348]",{"v":6.28517765045094,"d":"6.29"},{"v":2.21937820934682,"d":"2.22"},{"v":2.83195429421681,"d":"2.83"},{"v":1.50179798150889,"d":"1.50"},{"v":0.0651037663422878,"d":"0.07"},{"v":0.562118987756869,"d":"0.56"},"up","no"]
["MSTRG.3431","CD63","ENST00000257857;ENST00000552692;ENST00000548898;ENST00000552754;ENST00000548160;ENST00000420846;ENST00000551173;ENST00000552164;ENST00000546457;ENST00000555199;ENST00000546939;ENST00000549117;ENST00000548117;ENST00000552067;ENST00000550776;MSTRG.3431.1;ENST00000550050","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0006810(transport);GO:0015031(protein transport);GO:0005765(lysosomal membrane);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0042470(melanosome);GO:0005615(extracellular space);GO:0005764(lysosome);GO:0005768(endosome);GO:0031902(late endosome membrane);GO:0070062(extracellular exosome);GO:0010008(endosome membrane);GO:0005887(integral component of plasma membrane);GO:0043312(neutrophil degranulation);GO:0002576(platelet degranulation);GO:0031088(platelet dense granule membrane);GO:0032585(multivesicular body membrane);GO:0009986(cell surface);GO:0031226(intrinsic component of plasma membrane);GO:0016477(cell migration);GO:0035577(azurophil granule membrane);GO:1900746(regulation of vascular endothelial growth factor signaling pathway);GO:0007160(cell-matrix adhesion);GO:0005771(multivesicular body);GO:0002092(positive regulation of receptor internalization);GO:0034613(cellular protein localization);GO:0035646(endosome to melanosome transport);GO:0048757(pigment granule maturation);GO:2000680(regulation of rubidium ion transport);GO:2001046(positive regulation of integrin-mediated signaling pathway);GO:0031904(endosome lumen);GO:0097487(multivesicular body, internal vesicle);GO:0043473(pigmentation);GO:0050931(pigment cell differentiation);GO:0005770(late endosome);GO:0005770(late endosome)","04142(Lysosome);05205(Proteoglycans in cancer);05205(Proteoglycans in cancer)","K06497","NA","CD63 molecule [Source:HGNC Symbol;Acc:HGNC:1692]",{"v":25.8533777115108,"d":"25.85"},{"v":50.0787037021583,"d":"50.08"},{"v":0.516254930744075,"d":"0.52"},{"v":-0.953844439128055,"d":"-0.95"},{"v":0.0653099882451606,"d":"0.07"},{"v":0.563225114392898,"d":"0.56"},"down","no"]
["MSTRG.10457","TOMM22","ENST00000216034;ENST00000492561","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0006886(intracellular protein transport);GO:0015031(protein transport);GO:0071806(protein transmembrane transport);GO:0005741(mitochondrial outer membrane);GO:0005739(mitochondrion);GO:0005515(protein binding);GO:0006626(protein targeting to mitochondrion);GO:0015266(protein channel activity);GO:0030150(protein import into mitochondrial matrix);GO:0016236(macroautophagy);GO:0008320(protein transmembrane transporter activity);GO:0005742(mitochondrial outer membrane translocase complex);GO:0045040(protein import into mitochondrial outer membrane);GO:0031307(integral component of mitochondrial outer membrane);GO:0005743(mitochondrial inner membrane);GO:0005743(mitochondrial inner membrane)","NA","NA","NA","translocase of outer mitochondrial membrane 22 [Source:HGNC Symbol;Acc:HGNC:18002]",{"v":6.48782194705614,"d":"6.49"},{"v":12.6057565440438,"d":"12.61"},{"v":0.514671366560829,"d":"0.51"},{"v":-0.958276573601481,"d":"-0.96"},{"v":0.0653288753196618,"d":"0.07"},{"v":0.563225114392898,"d":"0.56"},"down","no"]
["ENSG00000221866","PLXNA4","ENST00000359827;ENST00000321063;ENST00000378539;ENST00000423507","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0007165(signal transduction);GO:0005886(plasma membrane);GO:0017154(semaphorin receptor activity);GO:0007399(nervous system development);GO:0007411(axon guidance);GO:0008045(motor neuron axon guidance);GO:0021602(cranial nerve morphogenesis);GO:0021610(facial nerve morphogenesis);GO:0021612(facial nerve structural organization);GO:0021615(glossopharyngeal nerve morphogenesis);GO:0021636(trigeminal nerve morphogenesis);GO:0021637(trigeminal nerve structural organization);GO:0021644(vagus nerve morphogenesis);GO:0021784(postganglionic parasympathetic fiber development);GO:0021785(branchiomotor neuron axon guidance);GO:0021793(chemorepulsion of branchiomotor axon);GO:0021960(anterior commissure morphogenesis);GO:0048485(sympathetic nervous system development);GO:0048812(neuron projection morphogenesis);GO:0048841(regulation of axon extension involved in axon guidance);GO:0050923(regulation of negative chemotaxis);GO:0071526(semaphorin-plexin signaling pathway);GO:1902287(semaphorin-plexin signaling pathway involved in axon guidance);GO:0002116(semaphorin receptor complex);GO:0002116(semaphorin receptor complex)","04360(Axon guidance);04360(Axon guidance)","K06820","NA","plexin A4 [Source:HGNC Symbol;Acc:HGNC:9102]",{"v":0.158176919618861,"d":"0.16"},{"v":0.0534325189347667,"d":"0.05"},{"v":2.96031186199498,"d":"2.96"},{"v":1.56574916843992,"d":"1.57"},{"v":0.0654333049623579,"d":"0.07"},{"v":0.563706951430165,"d":"0.56"},"up","no"]
["ENSG00000164933","SLC25A32","ENST00000297578;ENST00000523866;ENST00000523701","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005743(mitochondrial inner membrane);GO:0005739(mitochondrion);GO:0006839(mitochondrial transport);GO:0031966(mitochondrial membrane);GO:0035350(FAD transmembrane transport);GO:0008517(folic acid transporter activity);GO:0046655(folic acid metabolic process);GO:0015884(folic acid transport);GO:0015230(FAD transmembrane transporter activity);GO:0006544(glycine metabolic process);GO:1904947(folic acid import into mitochondrion);GO:1904947(folic acid import into mitochondrion)","NA","NA","NA","solute carrier family 25 member 32 [Source:HGNC Symbol;Acc:HGNC:29683]",{"v":1.23077676819923,"d":"1.23"},{"v":2.40603939135194,"d":"2.41"},{"v":0.511536416495519,"d":"0.51"},{"v":-0.96709114518587,"d":"-0.97"},{"v":0.065639685292713,"d":"0.07"},{"v":0.563940265045898,"d":"0.56"},"down","no"]
["MSTRG.11430","CCDC50","ENST00000392455;ENST00000392456;ENST00000460064","GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005515(protein binding);GO:0007605(sensory perception of sound);GO:0031625(ubiquitin protein ligase binding);GO:0031625(ubiquitin protein ligase binding)","NA","NA","NA","coiled-coil domain containing 50 [Source:HGNC Symbol;Acc:HGNC:18111]",{"v":1.23413264149098,"d":"1.23"},{"v":2.39626126918061,"d":"2.40"},{"v":0.515024241039036,"d":"0.52"},{"v":-0.957287756564802,"d":"-0.96"},{"v":0.0657071396103686,"d":"0.07"},{"v":0.563940265045898,"d":"0.56"},"down","no"]
["MSTRG.10422","CSF2RB","MSTRG.10422.2;MSTRG.10422.1;ENST00000403662;ENST00000406230;ENST00000421539","GO:0005622(intracellular);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0018108(peptidyl-tyrosine phosphorylation);GO:0043547(positive regulation of GTPase activity);GO:0005515(protein binding);GO:0007165(signal transduction);GO:0004896(cytokine receptor activity);GO:0005886(plasma membrane);GO:0019221(cytokine-mediated signaling pathway);GO:0005887(integral component of plasma membrane);GO:0044267(cellular protein metabolic process);GO:0000165(MAPK cascade);GO:0004872(receptor activity);GO:0005088(Ras guanyl-nucleotide exchange factor activity);GO:0004713(protein tyrosine kinase activity);GO:0007585(respiratory gaseous exchange);GO:0036016(cellular response to interleukin-3);GO:0038156(interleukin-3-mediated signaling pathway);GO:0004912(interleukin-3 receptor activity);GO:0004914(interleukin-5 receptor activity);GO:0032496(response to lipopolysaccharide);GO:0038043(interleukin-5-mediated signaling pathway);GO:0030526(granulocyte macrophage colony-stimulating factor receptor complex);GO:0030526(granulocyte macrophage colony-stimulating factor receptor complex)","04630(Jak-STAT signaling pathway);04060(Cytokine-cytokine receptor interaction);04210(Apoptosis);05200(Pathways in cancer);05200(Pathways in cancer)","K04738","NA","colony stimulating factor 2 receptor beta common subunit [Source:HGNC Symbol;Acc:HGNC:2436]",{"v":110.197945515521,"d":"110.20"},{"v":39.2531090593935,"d":"39.25"},{"v":2.80736859209755,"d":"2.81"},{"v":1.48921849423189,"d":"1.49"},{"v":0.0657110861242132,"d":"0.07"},{"v":0.563940265045898,"d":"0.56"},"up","no"]
["MSTRG.15015","SPTAN1","ENST00000372739;MSTRG.15015.7;ENST00000372731;ENST00000630804;ENST00000358161;ENST00000630866;ENST00000631121;ENST00000475367;ENST00000497216;ENST00000625282;ENST00000631315;ENST00000630147;ENST00000628867;ENST00000629137;ENST00000637820;ENST00000630763;ENST00000625980;ENST00000630981;ENST00000629047;ENST00000628614;ENST00000629378;ENST00000637434;ENST00000491712;ENST00000476825;ENST00000472211;ENST00000629089;ENST00000636010","GO:0005737(cytoplasm);GO:0043231(intracellular membrane-bounded organelle);GO:0046872(metal ion binding);GO:0005509(calcium ion binding);GO:0003779(actin binding);GO:0051693(actin filament capping);GO:0043547(positive regulation of GTPase activity);GO:0015630(microtubule cytoskeleton);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0007010(cytoskeleton organization);GO:0005576(extracellular region);GO:0005516(calmodulin binding);GO:0005829(cytosol);GO:0045296(cadherin binding);GO:0070062(extracellular exosome);GO:0005938(cell cortex);GO:0000165(MAPK cascade);GO:0043312(neutrophil degranulation);GO:0005200(structural constituent of cytoskeleton);GO:0016020(membrane);GO:0007411(axon guidance);GO:0035580(specific granule lumen);GO:1904724(tertiary granule lumen);GO:0006888(ER to Golgi vesicle-mediated transport);GO:0005088(Ras guanyl-nucleotide exchange factor activity);GO:1903561(extracellular vesicle);GO:0008091(spectrin);GO:0008091(spectrin)","04210(Apoptosis);04210(Apoptosis)","K06114","NA","spectrin alpha, non-erythrocytic 1 [Source:HGNC Symbol;Acc:HGNC:11273]",{"v":11.2084395852427,"d":"11.21"},{"v":3.98640430900468,"d":"3.99"},{"v":2.81166653365404,"d":"2.81"},{"v":1.49142549954154,"d":"1.49"},{"v":0.0657371512583693,"d":"0.07"},{"v":0.563940265045898,"d":"0.56"},"up","no"]
["MSTRG.11573","TLR1;TLR6","MSTRG.11573.5;MSTRG.11573.1;ENST00000381950;ENST00000505744;ENST00000514655;ENST00000436693;ENST00000505940;ENST00000508364;MSTRG.11573.2;ENST00000506146;MSTRG.11573.6;ENST00000508535;ENST00000515861;ENST00000509754;ENST00000508254;ENST00000308979;ENST00000510552;ENST00000502213","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0007165(signal transduction);GO:0005794(Golgi apparatus);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0004888(transmembrane signaling receptor activity);GO:0006954(inflammatory response);GO:0031410(cytoplasmic vesicle);GO:0045121(membrane raft);GO:0002376(immune system process);GO:0002755(MyD88-dependent toll-like receptor signaling pathway);GO:0045087(innate immune response);GO:0050707(regulation of cytokine secretion);GO:0030670(phagocytic vesicle membrane);GO:0042802(identical protein binding);GO:0005887(integral component of plasma membrane);GO:0034150(toll-like receptor 6 signaling pathway);GO:0042088(T-helper 1 type immune response);GO:0042496(detection of diacyl bacterial lipopeptide);GO:0045410(positive regulation of interleukin-6 biosynthetic process);GO:0002224(toll-like receptor signaling pathway);GO:0006955(immune response);GO:0004872(receptor activity);GO:0005102(receptor binding);GO:0046982(protein heterodimerization activity);GO:0010628(positive regulation of gene expression);GO:0035666(TRIF-dependent toll-like receptor signaling pathway);GO:0043032(positive regulation of macrophage activation);GO:0045429(positive regulation of nitric oxide biosynthetic process);GO:0050702(interleukin-1 beta secretion);GO:0051092(positive regulation of NF-kappaB transcription factor activity);GO:0140052(-);GO:1900017(positive regulation of cytokine production involved in inflammatory response);GO:1900227(positive regulation of NLRP3 inflammasome complex assembly);GO:1903223(positive regulation of oxidative stress-induced neuron death);GO:1903428(positive regulation of reactive oxygen species biosynthetic process);GO:1904646(cellular response to amyloid-beta);GO:0005622(intracellular);GO:0043235(receptor complex);GO:0007250(activation of NF-kappaB-inducing kinase activity);GO:0042742(defense response to bacterium);GO:0043123(positive regulation of I-kappaB kinase/NF-kappaB signaling);GO:0001775(cell activation);GO:0038124(toll-like receptor TLR6:TLR2 signaling pathway);GO:0071726(cellular response to diacyl bacterial lipopeptide);GO:0043507(positive regulation of JUN kinase activity);GO:0071723(lipopeptide binding);GO:0035663(Toll-like receptor 2 binding);GO:0034136(negative regulation of toll-like receptor 2 signaling pathway);GO:2000483(negative regulation of interleukin-8 secretion);GO:0035355(Toll-like receptor 2-Toll-like receptor 6 protein complex);GO:0001774(microglial cell activation);GO:0032493(response to bacterial lipoprotein);GO:0046209(nitric oxide metabolic process);GO:0034130(toll-like receptor 1 signaling pathway);GO:0042116(macrophage activation);GO:0042495(detection of triacyl bacterial lipopeptide);GO:0042535(positive regulation of tumor necrosis factor biosynthetic process);GO:0038123(toll-like receptor TLR1:TLR2 signaling pathway);GO:0071727(cellular response to triacyl bacterial lipopeptide);GO:2000484(positive regulation of interleukin-8 secretion);GO:0035354(Toll-like receptor 1-Toll-like receptor 2 protein complex);GO:0034137(positive regulation of toll-like receptor 2 signaling pathway);GO:0006952(defense response);GO:0006952(defense response)","04145(Phagosome);04620(Toll-like receptor signaling pathway);05152(Tuberculosis);05142(Chagas disease (American trypanosomiasis));05152(Tuberculosis)","K10169;K05398","NA","toll like receptor 6 [Source:HGNC Symbol;Acc:HGNC:16711];toll like receptor 1 [Source:HGNC Symbol;Acc:HGNC:11847]",{"v":11.7663049111795,"d":"11.77"},{"v":4.1899517323712,"d":"4.19"},{"v":2.80821967954286,"d":"2.81"},{"v":1.4896557982459,"d":"1.49"},{"v":0.0657401674252562,"d":"0.07"},{"v":0.563940265045898,"d":"0.56"},"up","no"]
["ENSG00000171105","INSR","ENST00000341500;ENST00000593970;ENST00000597211","GO:0008284(positive regulation of cell proliferation);GO:0046326(positive regulation of glucose import);GO:0051897(positive regulation of protein kinase B signaling);GO:0001934(positive regulation of protein phosphorylation);GO:0030335(positive regulation of cell migration);GO:0032148(activation of protein kinase B activity);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0004713(protein tyrosine kinase activity);GO:0007169(transmembrane receptor protein tyrosine kinase signaling pathway);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0004714(transmembrane receptor protein tyrosine kinase activity);GO:0023014(signal transduction by protein phosphorylation);GO:0005975(carbohydrate metabolic process);GO:0046777(protein autophosphorylation);GO:0035556(intracellular signal transduction);GO:0070062(extracellular exosome);GO:0010008(endosome membrane);GO:0043548(phosphatidylinositol 3-kinase binding);GO:0043560(insulin receptor substrate binding);GO:0000187(activation of MAPK activity);GO:0005622(intracellular);GO:0019904(protein domain specific binding);GO:0008286(insulin receptor signaling pathway);GO:0043235(receptor complex);GO:0032147(activation of protein kinase activity);GO:0003007(heart morphogenesis);GO:0032869(cellular response to insulin stimulus);GO:0045429(positive regulation of nitric oxide biosynthetic process);GO:0005887(integral component of plasma membrane);GO:0007612(learning);GO:0018108(peptidyl-tyrosine phosphorylation);GO:0005901(caveola);GO:0006355(regulation of transcription, DNA-templated);GO:0051290(protein heterotetramerization);GO:0045840(positive regulation of mitotic nuclear division);GO:0042593(glucose homeostasis);GO:0007186(G-protein coupled receptor signaling pathway);GO:0005525(GTP binding);GO:0043410(positive regulation of MAPK cascade);GO:0045740(positive regulation of DNA replication);GO:0005159(insulin-like growth factor receptor binding);GO:0045725(positive regulation of glycogen biosynthetic process);GO:0045821(positive regulation of glycolytic process);GO:0060267(positive regulation of respiratory burst);GO:1990535(neuron projection maintenance);GO:0009897(external side of plasma membrane);GO:0004716(signal transducer, downstream of receptor, with protein tyrosine kinase activity);GO:0005009(insulin-activated receptor activity);GO:0031994(insulin-like growth factor I binding);GO:0031995(insulin-like growth factor II binding);GO:0043559(insulin binding);GO:0051425(PTB domain binding);GO:0007613(memory);GO:0019087(transformation of host cell by virus);GO:0045995(regulation of embryonic development);GO:0048639(positive regulation of developmental growth);GO:0005899(insulin receptor complex);GO:0032590(dendrite membrane);GO:0032809(neuronal cell body membrane);GO:0008544(epidermis development);GO:0008584(male gonad development);GO:0009887(animal organ morphogenesis);GO:0030238(male sex determination);GO:0030325(adrenal gland development);GO:0031017(exocrine pancreas development);GO:0038083(peptidyl-tyrosine autophosphorylation);GO:0045893(positive regulation of transcription, DNA-templated);GO:0051446(positive regulation of meiotic cell cycle);GO:0071363(cellular response to growth factor stimulus);GO:2000194(regulation of female gonad development);GO:2000194(regulation of female gonad development)","04014(Ras signaling pathway);04015(Rap1 signaling pathway);04010(MAPK signaling pathway);04066(HIF-1 signaling pathway);04068(FoxO signaling pathway);04072(Phospholipase D signaling pathway);04022(cGMP - PKG signaling pathway);04151(PI3K-Akt signaling pathway);04152(AMPK signaling pathway);04150(mTOR signaling pathway);04520(Adherens junction);04910(Insulin signaling pathway);04923(Regulation of lipolysis in adipocyte);04913(Ovarian Steroidogenesis);04960(Aldosterone-regulated sodium reabsorption);04211(Longevity regulating pathway - mammal);04213(Longevity regulating pathway - multiple species);04930(Type II diabetes mellitus);04932(Non-alcoholic fatty liver disease (NAFLD));04931(Insulin resistance);04931(Insulin resistance)","K04527","EC:2.7.10.1","insulin receptor [Source:HGNC Symbol;Acc:HGNC:6091]",{"v":0.768002031288872,"d":"0.77"},{"v":0.268782780116735,"d":"0.27"},{"v":2.85733346070504,"d":"2.86"},{"v":1.5146694136045,"d":"1.51"},{"v":0.0658042109934796,"d":"0.07"},{"v":0.563940265045898,"d":"0.56"},"up","no"]
["MSTRG.13723","HIP1","ENST00000336926;ENST00000479835;ENST00000434438;ENST00000420909;ENST00000616821;ENST00000404944;MSTRG.13723.1","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0043231(intracellular membrane-bounded organelle);GO:0003779(actin binding);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0006897(endocytosis);GO:0006915(apoptotic process);GO:0005515(protein binding);GO:0007010(cytoskeleton organization);GO:0030154(cell differentiation);GO:0031410(cytoplasmic vesicle);GO:0005543(phospholipid binding);GO:0030276(clathrin binding);GO:0048268(clathrin coat assembly);GO:0030136(clathrin-coated vesicle);GO:0035091(phosphatidylinositol binding);GO:0072583(clathrin-dependent endocytosis);GO:0005829(cytosol);GO:0061024(membrane organization);GO:0012505(endomembrane system);GO:0030665(clathrin-coated vesicle membrane);GO:0030122(AP-2 adaptor complex);GO:0005154(epidermal growth factor receptor binding);GO:0005200(structural constituent of cytoskeleton);GO:0032051(clathrin light chain binding);GO:0032266(phosphatidylinositol-3-phosphate binding);GO:0035254(glutamate receptor binding);GO:0035612(AP-2 adaptor complex binding);GO:0035615(clathrin adaptor activity);GO:0042803(protein homodimerization activity);GO:0043325(phosphatidylinositol-3,4-bisphosphate binding);GO:0046982(protein heterodimerization activity);GO:0051015(actin filament binding);GO:0080025(phosphatidylinositol-3,5-bisphosphate binding);GO:0006919(activation of cysteine-type endopeptidase activity involved in apoptotic process);GO:0030100(regulation of endocytosis);GO:0042981(regulation of apoptotic process);GO:0045742(positive regulation of epidermal growth factor receptor signaling pathway);GO:0048260(positive regulation of receptor-mediated endocytosis);GO:0050821(protein stabilization);GO:0051897(positive regulation of protein kinase B signaling);GO:0097190(apoptotic signaling pathway);GO:0099637(neurotransmitter receptor transport);GO:2000588(positive regulation of platelet-derived growth factor receptor-beta signaling pathway);GO:0005794(Golgi apparatus);GO:0005856(cytoskeleton);GO:0031234(extrinsic component of cytoplasmic side of plasma membrane);GO:0098793(presynapse);GO:0098794(postsynapse);GO:0098888(extrinsic component of presynaptic membrane);GO:0098890(extrinsic component of postsynaptic membrane);GO:0098890(extrinsic component of postsynaptic membrane)","05016(Huntington's disease);05016(Huntington's disease)","K04559","NA","huntingtin interacting protein 1 [Source:HGNC Symbol;Acc:HGNC:4913]",{"v":3.51347094646475,"d":"3.51"},{"v":1.24761188194519,"d":"1.25"},{"v":2.81615700949144,"d":"2.82"},{"v":1.49372777094256,"d":"1.49"},{"v":0.0658870043184267,"d":"0.07"},{"v":0.563940265045898,"d":"0.56"},"up","no"]
["MSTRG.1344","MAPKAPK2","MSTRG.1344.3;ENST00000367103;ENST00000294981;ENST00000479009;ENST00000493447","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0005654(nucleoplasm);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0005813(centrosome);GO:0005515(protein binding);GO:0006974(cellular response to DNA damage stimulus);GO:0006954(inflammatory response);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0043488(regulation of mRNA stability);GO:0032496(response to lipopolysaccharide);GO:0005516(calmodulin binding);GO:0004871(signal transducer activity);GO:0048010(vascular endothelial growth factor receptor signaling pathway);GO:0031572(G2 DNA damage checkpoint);GO:0035924(cellular response to vascular endothelial growth factor stimulus);GO:0006950(response to stress);GO:0018105(peptidyl-serine phosphorylation);GO:1900034(regulation of cellular response to heat);GO:0000187(activation of MAPK activity);GO:0034097(response to cytokine);GO:0002224(toll-like receptor signaling pathway);GO:0007265(Ras protein signal transduction);GO:0032680(regulation of tumor necrosis factor production);GO:0070935(3'-UTR-mediated mRNA stabilization);GO:0006691(leukotriene metabolic process);GO:0000165(MAPK cascade);GO:0004683(calmodulin-dependent protein kinase activity);GO:0009931(calcium-dependent protein serine/threonine kinase activity);GO:0051019(mitogen-activated protein kinase binding);GO:0032675(regulation of interleukin-6 production);GO:0044351(macropinocytosis);GO:0046777(protein autophosphorylation);GO:0038066(p38MAPK cascade);GO:0042535(positive regulation of tumor necrosis factor biosynthetic process);GO:0048255(mRNA stabilization);GO:0048839(inner ear development);GO:0048839(inner ear development)","04010(MAPK signaling pathway);04370(VEGF signaling pathway);04218(Cellular senescence);04722(Neurotrophin signaling pathway);05203(Viral carcinogenesis);05167(Kaposi's sarcoma-associated herpesvirus infection);05167(Kaposi's sarcoma-associated herpesvirus infection)","K04443","EC:2.7.11.1","mitogen-activated protein kinase-activated protein kinase 2 [Source:HGNC Symbol;Acc:HGNC:6887]",{"v":21.0842798370264,"d":"21.08"},{"v":7.50132680795807,"d":"7.50"},{"v":2.81074006996447,"d":"2.81"},{"v":1.49095004314828,"d":"1.49"},{"v":0.0659033735611401,"d":"0.07"},{"v":0.563940265045898,"d":"0.56"},"up","no"]
["MSTRG.15268","EBP","ENST00000498425;ENST00000446158;ENST00000276096;ENST00000495186;ENST00000466461","GO:0005634(nucleus);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0000247(C-8 sterol isomerase activity);GO:0016853(isomerase activity);GO:0047750(cholestenol delta-isomerase activity);GO:0006695(cholesterol biosynthetic process);GO:0016125(sterol metabolic process);GO:0016126(sterol biosynthetic process);GO:0030097(hemopoiesis);GO:0005783(endoplasmic reticulum);GO:0043231(intracellular membrane-bounded organelle);GO:0006629(lipid metabolic process);GO:0005789(endoplasmic reticulum membrane);GO:0006694(steroid biosynthetic process);GO:0008202(steroid metabolic process);GO:0005515(protein binding);GO:0031410(cytoplasmic vesicle);GO:0008203(cholesterol metabolic process);GO:0007165(signal transduction);GO:0005887(integral component of plasma membrane);GO:0001501(skeletal system development);GO:0006855(drug transmembrane transport);GO:0004888(transmembrane signaling receptor activity);GO:0005635(nuclear envelope);GO:0033489(cholesterol biosynthetic process via desmosterol);GO:0033490(cholesterol biosynthetic process via lathosterol);GO:0004769(steroid delta-isomerase activity);GO:0015238(drug transmembrane transporter activity);GO:0015238(drug transmembrane transporter activity)","00100(Steroid biosynthesis);00100(Steroid biosynthesis)","K01824","EC:5.3.3.5","emopamil binding protein (sterol isomerase) [Source:HGNC Symbol;Acc:HGNC:3133]",{"v":1.8914004732254,"d":"1.89"},{"v":3.71019610128684,"d":"3.71"},{"v":0.509784502379642,"d":"0.51"},{"v":-0.972040579275155,"d":"-0.97"},{"v":0.0660357601347861,"d":"0.07"},{"v":0.563940265045898,"d":"0.56"},"down","no"]
["MSTRG.12422","YIPF5","ENST00000274496;ENST00000519064;ENST00000522203;ENST00000508754;ENST00000448443","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0015031(protein transport);GO:0005794(Golgi apparatus);GO:0043231(intracellular membrane-bounded organelle);GO:0005783(endoplasmic reticulum);GO:0005654(nucleoplasm);GO:0005789(endoplasmic reticulum membrane);GO:0005515(protein binding);GO:0031410(cytoplasmic vesicle);GO:0016192(vesicle-mediated transport);GO:0032580(Golgi cisterna membrane);GO:0030134(ER to Golgi transport vesicle);GO:0060628(regulation of ER to Golgi vesicle-mediated transport);GO:0042175(nuclear outer membrane-endoplasmic reticulum membrane network);GO:0070971(endoplasmic reticulum exit site);GO:0070971(endoplasmic reticulum exit site)","NA","NA","NA","Yip1 domain family member 5 [Source:HGNC Symbol;Acc:HGNC:24877]",{"v":2.69070017373683,"d":"2.69"},{"v":5.22445716590111,"d":"5.22"},{"v":0.515020046732978,"d":"0.52"},{"v":-0.957299505777183,"d":"-0.96"},{"v":0.0660416463458302,"d":"0.07"},{"v":0.563940265045898,"d":"0.56"},"down","no"]
["MSTRG.14850","FAM120A","ENST00000277165;ENST00000446420;ENST00000427765;ENST00000375389;ENST00000475933","GO:0005634(nucleus);GO:0003723(RNA binding);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0005886(plasma membrane)","NA","NA","NA","family with sequence similarity 120A [Source:HGNC Symbol;Acc:HGNC:13247]",{"v":15.9914885749584,"d":"15.99"},{"v":5.69616163714603,"d":"5.70"},{"v":2.80741481608845,"d":"2.81"},{"v":1.48924224835296,"d":"1.49"},{"v":0.0660449999616234,"d":"0.07"},{"v":0.563940265045898,"d":"0.56"},"up","no"]
["MSTRG.14423","C8orf59","ENST00000619594;ENST00000612977;ENST00000523245;ENST00000521286;ENST00000523281;ENST00000611854;ENST00000545322;ENST00000614462;ENST00000612809;ENST00000615071;ENST00000615697;ENST00000518786","NA","NA","NA","NA","chromosome 8 open reading frame 59 [Source:HGNC Symbol;Acc:HGNC:32235]",{"v":2.49245960143198,"d":"2.49"},{"v":4.87050412330947,"d":"4.87"},{"v":0.511745712215592,"d":"0.51"},{"v":-0.966500985555076,"d":"-0.97"},{"v":0.0660802649666892,"d":"0.07"},{"v":0.563940265045898,"d":"0.56"},"down","no"]
["MSTRG.14824","ZCCHC6","MSTRG.14824.1","NA","NA","NA","NA",null,{"v":10.886058,"d":"10.89"},{"v":3.834425,"d":"3.83"},{"v":2.83903271024991,"d":"2.84"},{"v":1.50539947133898,"d":"1.51"},{"v":0.0661082084672774,"d":"0.07"},{"v":0.563940265045898,"d":"0.56"},"up","no"]
["ENSG00000151748","SAV1","ENST00000324679;ENST00000556735;ENST00000555720;ENST00000602664","GO:0005829(cytosol);GO:0007165(signal transduction);GO:0035329(hippo signaling);GO:0032947(protein complex scaffold);GO:0006915(apoptotic process);GO:0042127(regulation of cell proliferation);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005515(protein binding);GO:0001942(hair follicle development);GO:0030216(keratinocyte differentiation);GO:0043065(positive regulation of apoptotic process);GO:0045600(positive regulation of fat cell differentiation);GO:0046620(regulation of organ growth);GO:0050680(negative regulation of epithelial cell proliferation);GO:0050821(protein stabilization);GO:0051091(positive regulation of sequence-specific DNA binding transcription factor activity);GO:0060044(negative regulation of cardiac muscle cell proliferation);GO:0060412(ventricular septum morphogenesis);GO:0060487(lung epithelial cell differentiation);GO:0060575(intestinal epithelial cell differentiation);GO:2000036(regulation of stem cell population maintenance);GO:0005622(intracellular);GO:0005622(intracellular)","04390(Hippo signaling pathway);04392(Hippo signaling pathway - multiple species);04392(Hippo signaling pathway - multiple species)","K16686","NA","salvador family WW domain containing protein 1 [Source:HGNC Symbol;Acc:HGNC:17795]",{"v":1.41301881598579,"d":"1.41"},{"v":0.493065988987567,"d":"0.49"},{"v":2.86578033680076,"d":"2.87"},{"v":1.51892803069098,"d":"1.52"},{"v":0.0661722965170893,"d":"0.07"},{"v":0.563940265045898,"d":"0.56"},"up","no"]
["ENSG00000148335","NTMT1","ENST00000372483;ENST00000617943;ENST00000372480;ENST00000372486;ENST00000459968;ENST00000611055;ENST00000481189;ENST00000482347;ENST00000372481","GO:0005634(nucleus);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0008168(methyltransferase activity);GO:0016740(transferase activity);GO:0032259(methylation);GO:0006480(N-terminal protein amino acid methylation);GO:0005737(cytoplasm);GO:0007059(chromosome segregation);GO:0007051(spindle organization);GO:0042054(histone methyltransferase activity);GO:0016571(histone methylation);GO:0008276(protein methyltransferase activity);GO:0071885(N-terminal protein N-methyltransferase activity);GO:0018011(N-terminal peptidyl-alanine methylation);GO:0018013(N-terminal peptidyl-glycine methylation);GO:0018016(N-terminal peptidyl-proline dimethylation);GO:0035572(N-terminal peptidyl-serine dimethylation);GO:0035573(N-terminal peptidyl-serine trimethylation);GO:0018012(N-terminal peptidyl-alanine trimethylation);GO:0018012(N-terminal peptidyl-alanine trimethylation)","NA","NA","NA","N-terminal Xaa-Pro-Lys N-methyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:23373]",{"v":0.890942780455596,"d":"0.89"},{"v":1.75179376064708,"d":"1.75"},{"v":0.508588853591132,"d":"0.51"},{"v":-0.975428251115366,"d":"-0.98"},{"v":0.0661888040349228,"d":"0.07"},{"v":0.563940265045898,"d":"0.56"},"down","no"]
["ENSG00000104549","SQLE","ENST00000265896;ENST00000518604;ENST00000520493;ENST00000521232;ENST00000523430;ENST00000518931","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016491(oxidoreductase activity);GO:0050660(flavin adenine dinucleotide binding);GO:0055114(oxidation-reduction process);GO:0004506(squalene monooxygenase activity);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0016126(sterol biosynthetic process);GO:0043231(intracellular membrane-bounded organelle);GO:0031090(organelle membrane);GO:0045540(regulation of cholesterol biosynthetic process);GO:0006695(cholesterol biosynthetic process);GO:0008203(cholesterol metabolic process);GO:0006725(cellular aromatic compound metabolic process);GO:0010033(response to organic substance);GO:0071949(FAD binding);GO:0071949(FAD binding)","00100(Steroid biosynthesis);00100(Steroid biosynthesis)","K00511","EC:1.14.14.17","squalene epoxidase [Source:HGNC Symbol;Acc:HGNC:11279]",{"v":0.867031692682927,"d":"0.87"},{"v":1.70074729175377,"d":"1.70"},{"v":0.509794545542898,"d":"0.51"},{"v":-0.972012157306591,"d":"-0.97"},{"v":0.0664026797887915,"d":"0.07"},{"v":0.565347742219381,"d":"0.57"},"down","no"]
["MSTRG.6257","AC240565.2","ENST00000623180","NA","NA","NA","NA",null,{"v":2.282974,"d":"2.28"},{"v":0.792511,"d":"0.79"},{"v":2.88068430595916,"d":"2.88"},{"v":1.52641156428722,"d":"1.53"},{"v":0.0665501973331408,"d":"0.07"},{"v":0.565774115395142,"d":"0.57"},"up","no"]
["ENSG00000149115","TNKS1BP1","ENST00000532273;ENST00000358252;ENST00000530920;ENST00000427750;ENST00000532437","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005694(chromosome);GO:0005856(cytoskeleton);GO:0006977(DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest);GO:0005829(cytosol);GO:0045296(cadherin binding);GO:0005515(protein binding);GO:0000289(nuclear-transcribed mRNA poly(A) tail shortening);GO:0030014(CCR4-NOT complex);GO:0005913(cell-cell adherens junction);GO:0033138(positive regulation of peptidyl-serine phosphorylation);GO:0019899(enzyme binding);GO:0010800(positive regulation of peptidyl-threonine phosphorylation);GO:0031954(positive regulation of protein autophosphorylation);GO:0071479(cellular response to ionizing radiation);GO:0005720(nuclear heterochromatin);GO:0044877(macromolecular complex binding);GO:0006302(double-strand break repair);GO:0071532(ankyrin repeat binding);GO:0007004(telomere maintenance via telomerase);GO:0007004(telomere maintenance via telomerase)","NA","NA","NA","tankyrase 1 binding protein 1 [Source:HGNC Symbol;Acc:HGNC:19081]",{"v":0.66759046719821,"d":"0.67"},{"v":0.232113269268429,"d":"0.23"},{"v":2.87614090009723,"d":"2.88"},{"v":1.5241343541125,"d":"1.52"},{"v":0.0665501973331408,"d":"0.07"},{"v":0.565774115395142,"d":"0.57"},"up","no"]
["MSTRG.12581","AC145098.1","ENST00000506025","NA","NA","NA","NA",null,{"v":7.992206,"d":"7.99"},{"v":2.762095,"d":"2.76"},{"v":2.89353045423854,"d":"2.89"},{"v":1.53283082846888,"d":"1.53"},{"v":0.06664027836521,"d":"0.07"},{"v":0.565841684607554,"d":"0.57"},"up","no"]
["MSTRG.8083","HCST","ENST00000246551;MSTRG.8083.1;ENST00000437550;MSTRG.8083.2","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005102(receptor binding);GO:0050776(regulation of immune response);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0043548(phosphatidylinositol 3-kinase binding);GO:0009986(cell surface);GO:0014068(positive regulation of phosphatidylinositol 3-kinase signaling);GO:0006468(protein phosphorylation);GO:0006468(protein phosphorylation)","04650(Natural killer cell mediated cytotoxicity);04650(Natural killer cell mediated cytotoxicity)","K07988","NA","hematopoietic cell signal transducer [Source:HGNC Symbol;Acc:HGNC:16977]",{"v":18.093464628866,"d":"18.09"},{"v":34.9977611294387,"d":"35.00"},{"v":0.516989202879224,"d":"0.52"},{"v":-0.951793944163899,"d":"-0.95"},{"v":0.0666555949834783,"d":"0.07"},{"v":0.565841684607554,"d":"0.57"},"down","no"]
["ENSG00000169857","AVEN","ENST00000306730;ENST00000558136","GO:0016020(membrane);GO:0006915(apoptotic process);GO:0005515(protein binding);GO:0005622(intracellular);GO:0012505(endomembrane system);GO:0043066(negative regulation of apoptotic process);GO:0043066(negative regulation of apoptotic process)","NA","NA","NA","apoptosis and caspase activation inhibitor [Source:HGNC Symbol;Acc:HGNC:13509]",{"v":0.748325035951327,"d":"0.75"},{"v":1.49296886117257,"d":"1.49"},{"v":0.501232849132296,"d":"0.50"},{"v":-0.996447127699069,"d":"-1.00"},{"v":0.0667242365129003,"d":"0.07"},{"v":0.56601063449548,"d":"0.57"},"down","no"]
["ENSG00000170017","ALCAM","ENST00000306107;ENST00000465413;ENST00000470756;ENST00000491388;ENST00000472644;ENST00000489178","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0007155(cell adhesion);GO:0005886(plasma membrane);GO:0042995(cell projection);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0002376(immune system process);GO:0005925(focal adhesion);GO:0030425(dendrite);GO:0002250(adaptive immune response);GO:0005887(integral component of plasma membrane);GO:0030424(axon);GO:0070062(extracellular exosome);GO:0007165(signal transduction);GO:0031226(intrinsic component of plasma membrane);GO:0005102(receptor binding);GO:0001772(immunological synapse);GO:0048846(axon extension involved in axon guidance);GO:0031290(retinal ganglion cell axon guidance);GO:0007157(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules);GO:0042101(T cell receptor complex);GO:1990138(neuron projection extension);GO:0007411(axon guidance);GO:0008045(motor neuron axon guidance);GO:0009897(external side of plasma membrane);GO:0043025(neuronal cell body);GO:0043025(neuronal cell body)","04514(Cell adhesion molecules (CAMs));04514(Cell adhesion molecules (CAMs))","K06547","NA","activated leukocyte cell adhesion molecule [Source:HGNC Symbol;Acc:HGNC:400]",{"v":2.49440126034267,"d":"2.49"},{"v":0.883397970469425,"d":"0.88"},{"v":2.82364386576209,"d":"2.82"},{"v":1.49755813906984,"d":"1.50"},{"v":0.0668137916175854,"d":"0.07"},{"v":0.5663566146387,"d":"0.57"},"up","no"]
["MSTRG.15018","WDR34","ENST00000372715;ENST00000483181;ENST00000473486;ENST00000451652","GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005856(cytoskeleton);GO:0042995(cell projection);GO:0005515(protein binding);GO:0035735(intraciliary transport involved in cilium assembly);GO:0005929(cilium);GO:0097542(ciliary tip);GO:0005814(centriole);GO:0060271(cilium assembly);GO:0005930(axoneme);GO:0036064(ciliary basal body);GO:0008574(ATP-dependent microtubule motor activity, plus-end-directed);GO:0045503(dynein light chain binding);GO:0045504(dynein heavy chain binding);GO:0005868(cytoplasmic dynein complex);GO:0042073(intraciliary transport);GO:0097014(ciliary plasm);GO:0097014(ciliary plasm)","NA","NA","NA","WD repeat domain 34 [Source:HGNC Symbol;Acc:HGNC:28296]",{"v":0.714936261136713,"d":"0.71"},{"v":1.4364039984639,"d":"1.44"},{"v":0.497726448757641,"d":"0.50"},{"v":-1.00657504225531,"d":"-1.01"},{"v":0.0669542721279038,"d":"0.07"},{"v":0.566646529839127,"d":"0.57"},"down","no"]
["MSTRG.8864","ELMOD3","ENST00000414593;ENST00000409013;ENST00000446464;ENST00000418268;ENST00000488150;ENST00000444108;ENST00000315658;ENST00000410106;ENST00000476734;ENST00000440462;ENST00000429764;ENST00000409344;ENST00000486908;ENST00000490508;ENST00000496957;ENST00000409890;ENST00000409331;ENST00000393852;ENST00000462396;ENST00000466467;ENST00000462891","GO:0043547(positive regulation of GTPase activity);GO:0005096(GTPase activator activity);GO:0005737(cytoplasm);GO:0005856(cytoskeleton);GO:0042995(cell projection);GO:0005515(protein binding);GO:0005929(cilium);GO:0032420(stereocilium);GO:0060091(kinocilium);GO:0060091(kinocilium)","NA","NA","NA","ELMO domain containing 3 [Source:HGNC Symbol;Acc:HGNC:26158]",{"v":0.807103024796804,"d":"0.81"},{"v":1.57510124645268,"d":"1.58"},{"v":0.512413425241392,"d":"0.51"},{"v":-0.964619820075389,"d":"-0.96"},{"v":0.0669939039899174,"d":"0.07"},{"v":0.566646529839127,"d":"0.57"},"down","no"]
["MSTRG.5533","ECI1","ENST00000566379;ENST00000561688;ENST00000570258;ENST00000563029;ENST00000562238;ENST00000563447","GO:0016853(isomerase activity);GO:0003824(catalytic activity);GO:0006629(lipid metabolic process);GO:0008152(metabolic process);GO:0006631(fatty acid metabolic process);GO:0005739(mitochondrion);GO:0005759(mitochondrial matrix);GO:0070062(extracellular exosome);GO:0006635(fatty acid beta-oxidation);GO:0004165(dodecenoyl-CoA delta-isomerase activity);GO:0004300(enoyl-CoA hydratase activity);GO:0016860(intramolecular oxidoreductase activity);GO:0005743(mitochondrial inner membrane);GO:0005743(mitochondrial inner membrane)","00071(Fatty acid degradation);00071(Fatty acid degradation)","K13238","EC:5.3.3.8","enoyl-CoA delta isomerase 1 [Source:HGNC Symbol;Acc:HGNC:2703]",{"v":0.985516435683364,"d":"0.99"},{"v":1.94206393382808,"d":"1.94"},{"v":0.507458286268039,"d":"0.51"},{"v":-0.97863885912672,"d":"-0.98"},{"v":0.0669943757400432,"d":"0.07"},{"v":0.566646529839127,"d":"0.57"},"down","no"]
["ENSG00000073150","PANX2","ENST00000395842;ENST00000402472;ENST00000159647","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0006811(ion transport);GO:0005886(plasma membrane);GO:0005921(gap junction);GO:0030054(cell junction);GO:0012505(endomembrane system);GO:0007267(cell-cell signaling);GO:0034214(protein hexamerization);GO:0022829(wide pore channel activity);GO:0055077(gap junction hemi-channel activity);GO:0006812(cation transport);GO:0015267(channel activity);GO:0002931(response to ischemia);GO:0055085(transmembrane transport);GO:0005737(cytoplasm);GO:0005737(cytoplasm)","NA","NA","NA","pannexin 2 [Source:HGNC Symbol;Acc:HGNC:8600]",{"v":6.15352015731786,"d":"6.15"},{"v":2.18580849258543,"d":"2.19"},{"v":2.81521468060512,"d":"2.82"},{"v":1.49324494249554,"d":"1.49"},{"v":0.0671735692266905,"d":"0.07"},{"v":0.567339820381202,"d":"0.57"},"up","no"]
["ENSG00000112877","CEP72","ENST00000264935;ENST00000514507;ENST00000499639;ENST00000512038","GO:0005737(cytoplasm);GO:0005813(centrosome);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0005815(microtubule organizing center);GO:0005829(cytosol);GO:0000086(G2/M transition of mitotic cell cycle);GO:0010389(regulation of G2/M transition of mitotic cell cycle);GO:0097711(ciliary basal body docking);GO:0007099(centriole replication);GO:0007051(spindle organization);GO:0034451(centriolar satellite);GO:0033566(gamma-tubulin complex localization);GO:0042802(identical protein binding);GO:1904779(regulation of protein localization to centrosome);GO:1904779(regulation of protein localization to centrosome)","NA","NA","NA","centrosomal protein 72 [Source:HGNC Symbol;Acc:HGNC:25547]",{"v":0.672155701476217,"d":"0.67"},{"v":0.225455651722253,"d":"0.23"},{"v":2.98132114383307,"d":"2.98"},{"v":1.57595178883488,"d":"1.58"},{"v":0.0671760852769366,"d":"0.07"},{"v":0.567339820381202,"d":"0.57"},"up","no"]
["ENSG00000197312","DDI2","ENST00000480945;ENST00000548451;ENST00000483899;ENST00000486680;ENST00000546927","GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0006508(proteolysis);GO:0042802(identical protein binding);GO:0043130(ubiquitin binding);GO:0043130(ubiquitin binding)","NA","NA","NA","DNA damage inducible 1 homolog 2 [Source:HGNC Symbol;Acc:HGNC:24578]",{"v":3.29703910678972,"d":"3.30"},{"v":1.17637016438695,"d":"1.18"},{"v":2.80272248192212,"d":"2.80"},{"v":1.48682889964117,"d":"1.49"},{"v":0.0672540093772495,"d":"0.07"},{"v":0.567339820381202,"d":"0.57"},"up","no"]
["ENSG00000155659","VSIG4","ENST00000455586;ENST00000374737;ENST00000412866;ENST00000427538","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0002376(immune system process);GO:0045087(innate immune response);GO:0070062(extracellular exosome);GO:0006957(complement activation, alternative pathway);GO:0032703(negative regulation of interleukin-2 production);GO:0042130(negative regulation of T cell proliferation);GO:0042130(negative regulation of T cell proliferation)","04610(Complement and coagulation cascades);04610(Complement and coagulation cascades)","K19822","NA","V-set and immunoglobulin domain containing 4 [Source:HGNC Symbol;Acc:HGNC:17032]",{"v":0.725600761861314,"d":"0.73"},{"v":1.4377501359489,"d":"1.44"},{"v":0.504677929578094,"d":"0.50"},{"v":-0.986565098372782,"d":"-0.99"},{"v":0.0672717586037127,"d":"0.07"},{"v":0.567339820381202,"d":"0.57"},"down","no"]
["ENSG00000101935","AMMECR1","ENST00000262844;ENST00000496695;ENST00000372059","GO:0005634(nucleus);GO:0005515(protein binding);GO:0003674(molecular_function);GO:0008150(biological_process);GO:0005575(cellular_component);GO:0005575(cellular_component)","NA","NA","NA","Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1 [Source:HGNC Symbol;Acc:HGNC:467]",{"v":0.324201206568447,"d":"0.32"},{"v":0.643058454266421,"d":"0.64"},{"v":0.504155111277224,"d":"0.50"},{"v":-0.988060424966839,"d":"-0.99"},{"v":0.0673386377983992,"d":"0.07"},{"v":0.56749172768709,"d":"0.57"},"down","no"]
["MSTRG.2940","HSPA8","MSTRG.2940.6;ENST00000453788;MSTRG.2940.1;ENST00000533540;ENST00000526110;ENST00000534624;ENST00000532091;ENST00000227378;ENST00000533238;ENST00000532182;ENST00000534319;ENST00000526686;ENST00000524552;ENST00000527983;ENST00000532780;ENST00000532636;ENST00000530391;ENST00000524590;ENST00000526862;ENST00000531063;ENST00000527387;ENST00000525624;ENST00000534567;ENST00000528292;ENST00000525463;ENST00000532167","GO:0003723(RNA binding);GO:0006397(mRNA processing);GO:0008380(RNA splicing);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0030529(intracellular ribonucleoprotein complex);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0005681(spliceosomal complex);GO:0042470(melanosome);GO:0005615(extracellular space);GO:0098793(presynapse);GO:0005730(nucleolus);GO:0005925(focal adhesion);GO:0005576(extracellular region);GO:0006986(response to unfolded protein);GO:0005654(nucleoplasm);GO:0045296(cadherin binding);GO:0070062(extracellular exosome);GO:0005622(intracellular);GO:0061024(membrane organization);GO:0072562(blood microparticle);GO:0043488(regulation of mRNA stability);GO:0016032(viral process);GO:0031012(extracellular matrix);GO:0006457(protein folding);GO:0043312(neutrophil degranulation);GO:0016887(ATPase activity);GO:0034774(secretory granule lumen);GO:1904813(ficolin-1-rich granule lumen);GO:0045892(negative regulation of transcription, DNA-templated);GO:0051082(unfolded protein binding);GO:0019899(enzyme binding);GO:0007269(neurotransmitter secretion);GO:0000398(mRNA splicing, via spliceosome);GO:0031625(ubiquitin protein ligase binding);GO:0000151(ubiquitin ligase complex);GO:1900034(regulation of cellular response to heat);GO:0042623(ATPase activity, coupled);GO:0001664(G-protein coupled receptor binding);GO:0031647(regulation of protein stability);GO:0006479(protein methylation);GO:0042026(protein refolding);GO:0031072(heat shock protein binding);GO:0023026(MHC class II protein complex binding);GO:0046034(ATP metabolic process);GO:0043254(regulation of protein complex assembly);GO:0061684(chaperone-mediated autophagy);GO:0043202(lysosomal lumen);GO:0055131(C3HC4-type RING finger domain binding);GO:0098575(lumenal side of lysosomal membrane);GO:0009267(cellular response to starvation);GO:0061635(regulation of protein complex stability);GO:0061740(protein targeting to lysosome involved in chaperone-mediated autophagy);GO:0061741(chaperone-mediated protein transport involved in chaperone-mediated autophagy);GO:1902904(negative regulation of supramolecular fiber organization);GO:1904589(regulation of protein import);GO:1904764(chaperone-mediated autophagy translocation complex disassembly);GO:0000974(Prp19 complex);GO:0005765(lysosomal membrane);GO:0061202(clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane);GO:0001786(phosphatidylserine binding);GO:0044788(modulation by host of viral process);GO:0044829(positive regulation by host of viral genome replication);GO:0048026(positive regulation of mRNA splicing, via spliceosome);GO:0051085(chaperone mediated protein folding requiring cofactor);GO:0051726(regulation of cell cycle);GO:0061738(late endosomal microautophagy);GO:0072318(clathrin coat disassembly);GO:0005770(late endosome);GO:0043209(myelin sheath);GO:0043209(myelin sheath)","03040(Spliceosome);04141(Protein processing in endoplasmic reticulum);04010(MAPK signaling pathway);04144(Endocytosis);04612(Antigen processing and presentation);04915(Estrogen signaling pathway);04213(Longevity regulating pathway - multiple species);05134(Legionellosis);05162(Measles);05164(Influenza A);05169(Epstein-Barr virus infection);05145(Toxoplasmosis);05145(Toxoplasmosis)","K03283","NA","heat shock protein family A (Hsp70) member 8 [Source:HGNC Symbol;Acc:HGNC:5241]",{"v":142.10049589227,"d":"142.10"},{"v":273.144846742544,"d":"273.14"},{"v":0.520238611809538,"d":"0.52"},{"v":-0.94275461563935,"d":"-0.94"},{"v":0.0673934232290999,"d":"0.07"},{"v":0.56754156922374,"d":"0.57"},"down","no"]
["MSTRG.4290","GZMB","ENST00000216341;ENST00000415355;ENST00000532263;ENST00000616551;ENST00000554242;ENST00000526004;ENST00000382542;ENST00000530830","GO:0016787(hydrolase activity);GO:0008233(peptidase activity);GO:0006508(proteolysis);GO:0004252(serine-type endopeptidase activity);GO:0008236(serine-type peptidase activity);GO:0005739(mitochondrion);GO:0005634(nucleus);GO:0016020(membrane);GO:0005515(protein binding);GO:0006915(apoptotic process);GO:0019835(cytolysis);GO:0005829(cytosol);GO:0030141(secretory granule);GO:1900740(positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway);GO:0001772(immunological synapse);GO:0042267(natural killer cell mediated cytotoxicity);GO:0008626(granzyme-mediated apoptotic signaling pathway);GO:0008626(granzyme-mediated apoptotic signaling pathway)","04210(Apoptosis);04650(Natural killer cell mediated cytotoxicity);05202(Transcriptional misregulation in cancers);05320(Autoimmune thyroid disease);05330(Allograft rejection);05332(Graft-versus-host disease);04940(Type I diabetes mellitus);04940(Type I diabetes mellitus)","K01353","EC:3.4.21.79","granzyme B [Source:HGNC Symbol;Acc:HGNC:4709]",{"v":42.2179108107725,"d":"42.22"},{"v":81.1966324053863,"d":"81.20"},{"v":0.519946573645977,"d":"0.52"},{"v":-0.94356470604879,"d":"-0.94"},{"v":0.0675785073850473,"d":"0.07"},{"v":0.568663702679742,"d":"0.57"},"down","no"]
["MSTRG.9087","NIFK","ENST00000285814;ENST00000477693;ENST00000447132;ENST00000498570","GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005730(nucleolus);GO:0005694(chromosome);GO:0005515(protein binding);GO:0005654(nucleoplasm);GO:0010923(negative regulation of phosphatase activity);GO:0000794(condensed nuclear chromosome);GO:0006461(protein complex assembly);GO:0009303(rRNA transcription);GO:0016072(rRNA metabolic process);GO:0016072(rRNA metabolic process)","NA","NA","NA","nucleolar protein interacting with the FHA domain of MKI67 [Source:HGNC Symbol;Acc:HGNC:17838]",{"v":3.12293679485084,"d":"3.12"},{"v":6.04275060563956,"d":"6.04"},{"v":0.516807162608411,"d":"0.52"},{"v":-0.952302029909652,"d":"-0.95"},{"v":0.0676550886164407,"d":"0.07"},{"v":0.568663702679742,"d":"0.57"},"down","no"]
["MSTRG.9839","ZNF217","MSTRG.9839.2;MSTRG.9839.5;ENST00000437222;ENST00000371471;ENST00000302342;ENST00000540425;ENST00000431687","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0005654(nucleoplasm);GO:0005515(protein binding);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:0001078(transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0007165(signal transduction);GO:0000118(histone deacetylase complex);GO:0007275(multicellular organism development);GO:0044212(transcription regulatory region DNA binding);GO:0045892(negative regulation of transcription, DNA-templated);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding)","NA","NA","NA","zinc finger protein 217 [Source:HGNC Symbol;Acc:HGNC:13009]",{"v":28.8005383534672,"d":"28.80"},{"v":10.318291930342,"d":"10.32"},{"v":2.79121181566653,"d":"2.79"},{"v":1.48089160982729,"d":"1.48"},{"v":0.067673575915216,"d":"0.07"},{"v":0.568663702679742,"d":"0.57"},"up","no"]
["MSTRG.5473","MPG","ENST00000356432;ENST00000219431;ENST00000475280;ENST00000397817;ENST00000436333","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0003677(DNA binding);GO:0003824(catalytic activity);GO:0006284(base-excision repair);GO:0003905(alkylbase DNA N-glycosylase activity);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016787(hydrolase activity);GO:0005739(mitochondrion);GO:0005515(protein binding);GO:0006281(DNA repair);GO:0006974(cellular response to DNA damage stimulus);GO:0005654(nucleoplasm);GO:0003684(damaged DNA binding);GO:0045007(depurination);GO:0042645(mitochondrial nucleoid);GO:0019104(DNA N-glycosylase activity);GO:0008725(DNA-3-methyladenine glycosylase activity);GO:0043916(DNA-7-methylguanine glycosylase activity);GO:0052821(DNA-7-methyladenine glycosylase activity);GO:0052822(DNA-3-methylguanine glycosylase activity);GO:0006307(DNA dealkylation involved in DNA repair);GO:0006307(DNA dealkylation involved in DNA repair)","03410(Base excision repair);03410(Base excision repair)","K03652","EC:3.2.2.21","N-methylpurine DNA glycosylase [Source:HGNC Symbol;Acc:HGNC:7211]",{"v":7.783638,"d":"7.78"},{"v":15.006282243227,"d":"15.01"},{"v":0.518691963395071,"d":"0.52"},{"v":-0.947050078106578,"d":"-0.95"},{"v":0.0678819282936764,"d":"0.07"},{"v":0.569549981926444,"d":"0.57"},"down","no"]
["ENSG00000107957","SH3PXD2A","ENST00000369774","GO:0005737(cytoplasm);GO:0043085(positive regulation of catalytic activity);GO:0042995(cell projection);GO:0005515(protein binding);GO:0030054(cell junction);GO:0035091(phosphatidylinositol binding);GO:0005829(cytosol);GO:0016176(superoxide-generating NADPH oxidase activator activity);GO:0006801(superoxide metabolic process);GO:0055114(oxidation-reduction process);GO:0071800(podosome assembly);GO:0002102(podosome);GO:0030198(extracellular matrix organization);GO:0072675(osteoclast fusion);GO:0072593(reactive oxygen species metabolic process)","NA","NA","NA","SH3 and PX domains 2A [Source:HGNC Symbol;Acc:HGNC:23664]",{"v":1.05189342293297,"d":"1.05"},{"v":0.373161657366451,"d":"0.37"},{"v":2.81886791466357,"d":"2.82"},{"v":1.49511587828991,"d":"1.50"},{"v":0.0679444468282671,"d":"0.07"},{"v":0.569549981926444,"d":"0.57"},"up","no"]
["MSTRG.6598","MYO18A;TIAF1","ENST00000530254;ENST00000531438;ENST00000585573;ENST00000533652;ENST00000531892;ENST00000527372;ENST00000527312;ENST00000532143;ENST00000590565;ENST00000588791;ENST00000528322;ENST00000533399;ENST00000636100;ENST00000531267;ENST00000359450;ENST00000528564;ENST00000533112;ENST00000590242;ENST00000530557;ENST00000529889;ENST00000529578;ENST00000531253;ENST00000533420","GO:0003723(RNA binding);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0003677(DNA binding);GO:0051015(actin filament binding);GO:0006259(DNA metabolic process);GO:0016459(myosin complex);GO:0005794(Golgi apparatus);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0000139(Golgi membrane);GO:0005802(trans-Golgi network);GO:0009986(cell surface);GO:0043066(negative regulation of apoptotic process);GO:0016477(cell migration);GO:0050714(positive regulation of protein secretion);GO:0007030(Golgi organization);GO:0005793(endoplasmic reticulum-Golgi intermediate compartment);GO:0043030(regulation of macrophage activation);GO:0043531(ADP binding);GO:0031032(actomyosin structure organization);GO:0042641(actomyosin);GO:0048194(Golgi vesicle budding);GO:0090161(Golgi ribbon formation);GO:0090164(asymmetric Golgi ribbon formation);GO:1903028(positive regulation of opsonization);GO:0003774(motor activity);GO:0008094(DNA-dependent ATPase activity);GO:0005634(nucleus);GO:0006915(apoptotic process);GO:0003674(molecular_function);GO:0007249(I-kappaB kinase/NF-kappaB signaling);GO:0008094(DNA-dependent ATPase activity)","NA","NA","NA","myosin XVIIIA [Source:HGNC Symbol;Acc:HGNC:31104];TGFB1-induced anti-apoptotic factor 1 [Source:HGNC Symbol;Acc:HGNC:11803]",{"v":3.34615646924697,"d":"3.35"},{"v":1.19445593528173,"d":"1.19"},{"v":2.80140637290042,"d":"2.80"},{"v":1.48615127639482,"d":"1.49"},{"v":0.067967998313213,"d":"0.07"},{"v":0.569549981926444,"d":"0.57"},"up","no"]
["ENSG00000188033","ZNF490","ENST00000311437;ENST00000414906;ENST00000465656","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0005622(intracellular);GO:0005515(protein binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding)","NA","NA","NA","zinc finger protein 490 [Source:HGNC Symbol;Acc:HGNC:23705]",{"v":0.235462668156879,"d":"0.24"},{"v":0.473519500101605,"d":"0.47"},{"v":0.497260763508905,"d":"0.50"},{"v":-1.00792549548675,"d":"-1.01"},{"v":0.0679752238827221,"d":"0.07"},{"v":0.569549981926444,"d":"0.57"},"down","no"]
["MSTRG.10349","ZMAT5","ENST00000344318;MSTRG.10349.2;ENST00000489010","GO:0003676(nucleic acid binding);GO:0006397(mRNA processing);GO:0008380(RNA splicing);GO:0005634(nucleus);GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0005654(nucleoplasm);GO:0005681(spliceosomal complex);GO:0000398(mRNA splicing, via spliceosome);GO:0005689(U12-type spliceosomal complex);GO:0005689(U12-type spliceosomal complex)","NA","NA","NA","zinc finger matrin-type 5 [Source:HGNC Symbol;Acc:HGNC:28046]",{"v":2.27635517487685,"d":"2.28"},{"v":4.40525769796798,"d":"4.41"},{"v":0.516735984804446,"d":"0.52"},{"v":-0.952500740268715,"d":"-0.95"},{"v":0.0680870161086164,"d":"0.07"},{"v":0.570046919236694,"d":"0.57"},"down","no"]
["MSTRG.2208","TIMM10B;DNHD1;AC084337.2","ENST00000254616;ENST00000254579;ENST00000640959;ENST00000533635;ENST00000354685;ENST00000533379;ENST00000525883;ENST00000532467;ENST00000531462;ENST00000528908;ENST00000530751;ENST00000533649;ENST00000473019;ENST00000529821;ENST00000472080;ENST00000532027;ENST00000534210","GO:0006810(transport);GO:0016020(membrane);GO:0015031(protein transport);GO:0046872(metal ion binding);GO:0005743(mitochondrial inner membrane);GO:0005739(mitochondrion);GO:0005515(protein binding);GO:0005758(mitochondrial intermembrane space);GO:0007160(cell-matrix adhesion);GO:0006626(protein targeting to mitochondrion);GO:0042719(mitochondrial intermembrane space protein transporter complex);GO:0003777(microtubule motor activity);GO:0007018(microtubule-based movement);GO:0030286(dynein complex);GO:0070062(extracellular exosome);GO:0051959(dynein light intermediate chain binding);GO:0045503(dynein light chain binding);GO:0045505(dynein intermediate chain binding);GO:0008569(ATP-dependent microtubule motor activity, minus-end-directed);GO:0003341(cilium movement);GO:0036159(inner dynein arm assembly);GO:0036156(inner dynein arm);GO:0036156(inner dynein arm)","NA","NA","NA","translocase of inner mitochondrial membrane 10B [Source:HGNC Symbol;Acc:HGNC:4022];dynein heavy chain domain 1 [Source:HGNC Symbol;Acc:HGNC:26532]",{"v":0.585721762814292,"d":"0.59"},{"v":0.208747043581826,"d":"0.21"},{"v":2.80589249439931,"d":"2.81"},{"v":1.48845973427208,"d":"1.49"},{"v":0.0681751717687819,"d":"0.07"},{"v":0.570046919236694,"d":"0.57"},"up","no"]
["MSTRG.15049","PRRC2B","MSTRG.15049.2;ENST00000405995;ENST00000320547;ENST00000465931;ENST00000357304;ENST00000458550;ENST00000451855","GO:0003723(RNA binding);GO:0005515(protein binding);GO:0030154(cell differentiation);GO:0030154(cell differentiation)","NA","NA","NA","proline rich coiled-coil 2B [Source:HGNC Symbol;Acc:HGNC:28121]",{"v":10.4028528491134,"d":"10.40"},{"v":3.729896893932,"d":"3.73"},{"v":2.78904568810932,"d":"2.79"},{"v":1.4797715677362,"d":"1.48"},{"v":0.0681817937500876,"d":"0.07"},{"v":0.570046919236694,"d":"0.57"},"up","no"]
["MSTRG.12998","PPIL1","ENST00000373699;ENST00000483552","GO:0006397(mRNA processing);GO:0008380(RNA splicing);GO:0016853(isomerase activity);GO:0003755(peptidyl-prolyl cis-trans isomerase activity);GO:0000413(protein peptidyl-prolyl isomerization);GO:0006457(protein folding);GO:0005515(protein binding);GO:0005681(spliceosomal complex);GO:0005654(nucleoplasm);GO:0070062(extracellular exosome);GO:0000398(mRNA splicing, via spliceosome);GO:0071013(catalytic step 2 spliceosome);GO:0097718(disordered domain specific binding);GO:0097718(disordered domain specific binding)","03040(Spliceosome);03040(Spliceosome)","K12733","EC:5.2.1.8","peptidylprolyl isomerase like 1 [Source:HGNC Symbol;Acc:HGNC:9260]",{"v":2.72639555303867,"d":"2.73"},{"v":5.29286747790055,"d":"5.29"},{"v":0.515107465739934,"d":"0.52"},{"v":-0.957054644890368,"d":"-0.96"},{"v":0.068409849901134,"d":"0.07"},{"v":0.571005741867309,"d":"0.57"},"down","no"]
["MSTRG.1011","ATP8B2","MSTRG.1011.1;MSTRG.1011.6;ENST00000368489;ENST00000368490;ENST00000426445;ENST00000368487;ENST00000514107;ENST00000505882","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0000287(magnesium ion binding);GO:0016787(hydrolase activity);GO:0005794(Golgi apparatus);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005886(plasma membrane);GO:0006869(lipid transport);GO:0004012(phospholipid-translocating ATPase activity);GO:0015914(phospholipid transport);GO:0045332(phospholipid translocation);GO:0034220(ion transmembrane transport);GO:0007030(Golgi organization);GO:0007030(Golgi organization)","NA","NA","NA","ATPase phospholipid transporting 8B2 [Source:HGNC Symbol;Acc:HGNC:13534]",{"v":11.7020839022715,"d":"11.70"},{"v":4.1958997951664,"d":"4.20"},{"v":2.78893311888718,"d":"2.79"},{"v":1.47971333766248,"d":"1.48"},{"v":0.068425466942811,"d":"0.07"},{"v":0.571005741867309,"d":"0.57"},"up","no"]
["MSTRG.2492","MARK2","ENST00000502399;ENST00000509502;ENST00000508192;MSTRG.2492.12;ENST00000402010;ENST00000543220;ENST00000543674;ENST00000425897;ENST00000408948;ENST00000535116;ENST00000377810;ENST00000540169;ENST00000350490;ENST00000513765;ENST00000361128;ENST00000512060","GO:0003723(RNA binding);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0005654(nucleoplasm);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0005886(plasma membrane);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0007275(multicellular organism development);GO:0016055(Wnt signaling pathway);GO:0000287(magnesium ion binding);GO:0030154(cell differentiation);GO:0000226(microtubule cytoskeleton organization);GO:0030010(establishment of cell polarity);GO:0008289(lipid binding);GO:0045296(cadherin binding);GO:0016328(lateral plasma membrane);GO:0046777(protein autophosphorylation);GO:0005739(mitochondrion);GO:0035556(intracellular signal transduction);GO:0005884(actin filament);GO:0051493(regulation of cytoskeleton organization);GO:0050770(regulation of axonogenesis);GO:0010976(positive regulation of neuron projection development);GO:0001764(neuron migration);GO:0097427(microtubule bundle);GO:0000422(mitophagy);GO:0018107(peptidyl-threonine phosphorylation);GO:0050321(tau-protein kinase activity);GO:0045197(establishment or maintenance of epithelial cell apical/basal polarity);GO:0032147(activation of protein kinase activity);GO:0051646(mitochondrion localization);GO:0030295(protein kinase activator activity);GO:0030295(protein kinase activator activity)","NA","NA","NA","microtubule affinity regulating kinase 2 [Source:HGNC Symbol;Acc:HGNC:3332]",{"v":9.09521396051349,"d":"9.10"},{"v":3.24699640672733,"d":"3.25"},{"v":2.80111611508699,"d":"2.80"},{"v":1.48600178890619,"d":"1.49"},{"v":0.0684439845586234,"d":"0.07"},{"v":0.571005741867309,"d":"0.57"},"up","no"]
["MSTRG.14707","SMIM27","ENST00000453396;ENST00000635960;ENST00000451672;ENST00000425533","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016021(integral component of membrane)","NA","NA","NA","small integral membrane protein 27 [Source:HGNC Symbol;Acc:HGNC:31420]",{"v":1.74343690808416,"d":"1.74"},{"v":3.36878879761905,"d":"3.37"},{"v":0.517526331516052,"d":"0.52"},{"v":-0.950295826707871,"d":"-0.95"},{"v":0.0687115792535213,"d":"0.07"},{"v":0.57265500423972,"d":"0.57"},"down","no"]
["ENSG00000117222","RBBP5","ENST00000264515;ENST00000367164","GO:0005634(nucleus);GO:0005730(nucleolus);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0016569(covalent chromatin modification);GO:0005515(protein binding);GO:0051568(histone H3-K4 methylation);GO:0005654(nucleoplasm);GO:0043687(post-translational protein modification);GO:0044212(transcription regulatory region DNA binding);GO:1904837(beta-catenin-TCF complex assembly);GO:0035097(histone methyltransferase complex);GO:0071339(MLL1 complex);GO:0035064(methylated histone binding);GO:0018024(histone-lysine N-methyltransferase activity);GO:0043627(response to estrogen);GO:0045652(regulation of megakaryocyte differentiation);GO:0044666(MLL3/4 complex);GO:0042800(histone methyltransferase activity (H3-K4 specific));GO:0048188(Set1C/COMPASS complex);GO:0006974(cellular response to DNA damage stimulus);GO:0006974(cellular response to DNA damage stimulus)","NA","NA","NA","RB binding protein 5, histone lysine methyltransferase complex subunit [Source:HGNC Symbol;Acc:HGNC:9888]",{"v":6.53199791008174,"d":"6.53"},{"v":2.33743917847411,"d":"2.34"},{"v":2.79451032148176,"d":"2.79"},{"v":1.48259550358294,"d":"1.48"},{"v":0.0687505127856936,"d":"0.07"},{"v":0.57265500423972,"d":"0.57"},"up","no"]
["ENSG00000100104","SRRD","ENST00000215917;ENST00000471799;ENST00000477945","GO:0048511(rhythmic process);GO:0048511(rhythmic process)","NA","NA","NA","SRR1 domain containing [Source:HGNC Symbol;Acc:HGNC:33910]",{"v":1.22747485274369,"d":"1.23"},{"v":2.3767890349618,"d":"2.38"},{"v":0.516442492239711,"d":"0.52"},{"v":-0.953320386222396,"d":"-0.95"},{"v":0.0687896091375536,"d":"0.07"},{"v":0.57265500423972,"d":"0.57"},"down","no"]
["MSTRG.10881","SETD2","ENST00000409792;ENST00000492397;ENST00000412450;ENST00000431180;ENST00000638947;ENST00000484689;ENST00000479832;ENST00000445387;ENST00000330022","GO:0005634(nucleus);GO:0018024(histone-lysine N-methyltransferase activity);GO:0034968(histone lysine methylation);GO:0008168(methyltransferase activity);GO:0016740(transferase activity);GO:0032259(methylation);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0016569(covalent chromatin modification);GO:0005694(chromosome);GO:0005515(protein binding);GO:0006368(transcription elongation from RNA polymerase II promoter);GO:0006298(mismatch repair);GO:0005654(nucleoplasm);GO:0010793(regulation of mRNA export from nucleus);GO:0046975(histone methyltransferase activity (H3-K36 specific));GO:0001525(angiogenesis);GO:0001570(vasculogenesis);GO:0001763(morphogenesis of a branching structure);GO:0001843(neural tube closure);GO:0010452(histone H3-K36 methylation);GO:0010468(regulation of gene expression);GO:0018023(peptidyl-lysine trimethylation);GO:0030900(forebrain development);GO:0034728(nucleosome organization);GO:0035441(cell migration involved in vasculogenesis);GO:0048332(mesoderm morphogenesis);GO:0048568(embryonic organ development);GO:0048701(embryonic cranial skeleton morphogenesis);GO:0048864(stem cell development);GO:0060039(pericardium development);GO:0060669(embryonic placenta morphogenesis);GO:0060977(coronary vasculature morphogenesis);GO:0097198(histone H3-K36 trimethylation);GO:0097676(histone H3-K36 dimethylation);GO:0097676(histone H3-K36 dimethylation)","00310(Lysine degradation);00310(Lysine degradation)","K11423","EC:2.1.1.43","SET domain containing 2 [Source:HGNC Symbol;Acc:HGNC:18420]",{"v":8.39852190662442,"d":"8.40"},{"v":3.01921116268938,"d":"3.02"},{"v":2.7816941095115,"d":"2.78"},{"v":1.47596378186643,"d":"1.48"},{"v":0.0688623165287152,"d":"0.07"},{"v":0.572849628830924,"d":"0.57"},"up","no"]
["MSTRG.12245","EPB41L4A","ENST00000261486;ENST00000514203;ENST00000511405;ENST00000513333;ENST00000515047;ENST00000621003","GO:0005737(cytoplasm);GO:0005856(cytoskeleton);GO:0008092(cytoskeletal protein binding);GO:0003674(molecular_function);GO:0008150(biological_process);GO:0005575(cellular_component);GO:0005200(structural constituent of cytoskeleton);GO:0031032(actomyosin structure organization);GO:0031032(actomyosin structure organization)","NA","NA","NA","erythrocyte membrane protein band 4.1 like 4A [Source:HGNC Symbol;Acc:HGNC:13278]",{"v":0.286728852481939,"d":"0.29"},{"v":0.0976452944535073,"d":"0.10"},{"v":2.93643287253808,"d":"2.94"},{"v":1.55406465790571,"d":"1.55"},{"v":0.0689640060747808,"d":"0.07"},{"v":0.57328489802894,"d":"0.57"},"up","no"]
["ENSG00000142197","DOPEY2","ENST00000399151;ENST00000463668;ENST00000270190;ENST00000492760","GO:0006810(transport);GO:0015031(protein transport);GO:0005829(cytosol);GO:0007275(multicellular organism development);GO:0003674(molecular_function);GO:0070062(extracellular exosome);GO:0005768(endosome);GO:0005802(trans-Golgi network);GO:0006895(Golgi to endosome transport);GO:0050890(cognition);GO:0000139(Golgi membrane);GO:0007029(endoplasmic reticulum organization);GO:0007029(endoplasmic reticulum organization)","NA","NA","NA","dopey family member 2 [Source:HGNC Symbol;Acc:HGNC:1291]",{"v":3.91754919368771,"d":"3.92"},{"v":1.40366547286822,"d":"1.40"},{"v":2.79094219342923,"d":"2.79"},{"v":1.48075224331597,"d":"1.48"},{"v":0.0690182591824709,"d":"0.07"},{"v":0.573325496341941,"d":"0.57"},"up","no"]
["MSTRG.6928","PLEKHM1","ENST00000579197;ENST00000581448;ENST00000430334;ENST00000579131;ENST00000581932;ENST00000586084;ENST00000586562;ENST00000582035;ENST00000580404;ENST00000585506;ENST00000591580;ENST00000580205;ENST00000583150;ENST00000590991","GO:0006810(transport);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0015031(protein transport);GO:0043231(intracellular membrane-bounded organelle);GO:0046872(metal ion binding);GO:0005730(nucleolus);GO:0035556(intracellular signal transduction);GO:0005765(lysosomal membrane);GO:0006914(autophagy);GO:0005764(lysosome);GO:0005768(endosome);GO:0010008(endosome membrane);GO:0005622(intracellular);GO:0005622(intracellular)","NA","NA","NA","pleckstrin homology and RUN domain containing M1 [Source:HGNC Symbol;Acc:HGNC:29017]",{"v":6.67154290988844,"d":"6.67"},{"v":2.39292083331528,"d":"2.39"},{"v":2.78803327590463,"d":"2.79"},{"v":1.47924778025085,"d":"1.48"},{"v":0.0691471683873997,"d":"0.07"},{"v":0.573888593466359,"d":"0.57"},"up","no"]
["MSTRG.4179","MRPL52","ENST00000397496;ENST00000355151;ENST00000557543;ENST00000553965;ENST00000557221;ENST00000556654;ENST00000556214;ENST00000555345;ENST00000553711;ENST00000311892;ENST00000555536;ENST00000556465;ENST00000553482;ENST00000397505;ENST00000556840;ENST00000432849;ENST00000461594","GO:0006412(translation);GO:0030529(intracellular ribonucleoprotein complex);GO:0003735(structural constituent of ribosome);GO:0005840(ribosome);GO:0005739(mitochondrion);GO:0005762(mitochondrial large ribosomal subunit);GO:0032543(mitochondrial translation);GO:0005743(mitochondrial inner membrane);GO:0070125(mitochondrial translational elongation);GO:0070126(mitochondrial translational termination);GO:0070126(mitochondrial translational termination)","NA","NA","NA","mitochondrial ribosomal protein L52 [Source:HGNC Symbol;Acc:HGNC:16655]",{"v":1.39806693713041,"d":"1.40"},{"v":2.72203282975412,"d":"2.72"},{"v":0.513611342908269,"d":"0.51"},{"v":-0.961251030712178,"d":"-0.96"},{"v":0.0692473951957619,"d":"0.07"},{"v":0.573888593466359,"d":"0.57"},"down","no"]
["ENSG00000041988","THAP3","ENST00000307896;ENST00000472925;ENST00000377627;ENST00000484676;ENST00000054650;ENST00000480647;ENST00000487819","GO:0003676(nucleic acid binding);GO:0046872(metal ion binding);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0005515(protein binding)","NA","NA","NA","THAP domain containing 3 [Source:HGNC Symbol;Acc:HGNC:20855]",{"v":0.831336060658153,"d":"0.83"},{"v":1.61612100761297,"d":"1.62"},{"v":0.514402112677222,"d":"0.51"},{"v":-0.959031526982986,"d":"-0.96"},{"v":0.0693297700471159,"d":"0.07"},{"v":0.573888593466359,"d":"0.57"},"down","no"]
["ENSG00000161653","NAGS","ENST00000592915;ENST00000293404","GO:0016740(transferase activity);GO:0005739(mitochondrion);GO:0016746(transferase activity, transferring acyl groups);GO:0005759(mitochondrial matrix);GO:0000050(urea cycle);GO:0004042(acetyl-CoA:L-glutamate N-acetyltransferase activity);GO:0006526(arginine biosynthetic process);GO:0006536(glutamate metabolic process);GO:0034618(arginine binding);GO:0034618(arginine binding)","00220(Arginine biosynthesis);00220(Arginine biosynthesis)","K11067","EC:2.3.1.1","N-acetylglutamate synthase [Source:HGNC Symbol;Acc:HGNC:17996]",{"v":0.264619691708009,"d":"0.26"},{"v":0.540421248405386,"d":"0.54"},{"v":0.489654491729959,"d":"0.49"},{"v":-1.0301639760438,"d":"-1.03"},{"v":0.0693496095097046,"d":"0.07"},{"v":0.573888593466359,"d":"0.57"},"down","no"]
["MSTRG.1497","HNRNPU","MSTRG.1497.4;ENST00000640218;ENST00000444376;ENST00000440865;ENST00000640657;ENST00000639824;ENST00000639667;ENST00000639880;ENST00000638716;ENST00000638589;ENST00000638230;ENST00000638952;ENST00000283179;ENST00000638301;ENST00000366527;ENST00000475997;ENST00000640001;ENST00000468690;ENST00000476241;ENST00000366525;ENST00000483966;ENST00000639628;ENST00000640264;MSTRG.1497.1;ENST00000640056;ENST00000638475;ENST00000640440;ENST00000640119;ENST00000465881","GO:0005634(nucleus);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0003723(RNA binding);GO:0006397(mRNA processing);GO:0008380(RNA splicing);GO:0005737(cytoplasm);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0005654(nucleoplasm);GO:0003677(DNA binding);GO:0030529(intracellular ribonucleoprotein complex);GO:0005515(protein binding);GO:0005681(spliceosomal complex);GO:0048511(rhythmic process);GO:0001047(core promoter binding);GO:0031012(extracellular matrix);GO:0000398(mRNA splicing, via spliceosome);GO:0009986(cell surface);GO:0032922(circadian regulation of gene expression);GO:0036464(cytoplasmic ribonucleoprotein granule);GO:0070034(telomerase RNA binding);GO:0005697(telomerase holoenzyme complex);GO:0016070(RNA metabolic process);GO:0006396(RNA processing);GO:0071013(catalytic step 2 spliceosome);GO:0001649(osteoblast differentiation);GO:0070934(CRD-mediated mRNA stabilization);GO:0070937(CRD-mediated mRNA stability complex);GO:0032211(negative regulation of telomere maintenance via telomerase);GO:0034046(poly(G) binding);GO:0035326(enhancer binding);GO:0043021(ribonucleoprotein complex binding);GO:0010628(positive regulation of gene expression);GO:0055013(cardiac muscle cell development);GO:0071549(cellular response to dexamethasone stimulus);GO:2000373(positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity);GO:2000373(positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity)","03040(Spliceosome);03040(Spliceosome)","K12888","NA","heterogeneous nuclear ribonucleoprotein U [Source:HGNC Symbol;Acc:HGNC:5048]",{"v":12.4586072269012,"d":"12.46"},{"v":4.48713414250178,"d":"4.49"},{"v":2.77651766834743,"d":"2.78"},{"v":1.47327657653693,"d":"1.47"},{"v":0.0693795893010915,"d":"0.07"},{"v":0.573888593466359,"d":"0.57"},"up","no"]
["MSTRG.5175","PPIB","ENST00000300026;ENST00000558492;ENST00000561048","GO:0003723(RNA binding);GO:0005634(nucleus);GO:0016020(membrane);GO:0016853(isomerase activity);GO:0005783(endoplasmic reticulum);GO:0003755(peptidyl-prolyl cis-trans isomerase activity);GO:0000413(protein peptidyl-prolyl isomerization);GO:0006457(protein folding);GO:0005515(protein binding);GO:0042470(melanosome);GO:0048471(perinuclear region of cytoplasm);GO:0005925(focal adhesion);GO:0005788(endoplasmic reticulum lumen);GO:0070062(extracellular exosome);GO:0050821(protein stabilization);GO:0060348(bone development);GO:0070063(RNA polymerase binding);GO:0032403(protein complex binding);GO:0061077(chaperone-mediated protein folding);GO:0051082(unfolded protein binding);GO:0005518(collagen binding);GO:0032991(macromolecular complex);GO:0044794(positive regulation by host of viral process);GO:0040018(positive regulation of multicellular organism growth);GO:0044829(positive regulation by host of viral genome replication);GO:0005790(smooth endoplasmic reticulum);GO:0034663(endoplasmic reticulum chaperone complex);GO:0034663(endoplasmic reticulum chaperone complex)","NA","NA","NA","peptidylprolyl isomerase B [Source:HGNC Symbol;Acc:HGNC:9255]",{"v":42.8823010915751,"d":"42.88"},{"v":81.9536447153323,"d":"81.95"},{"v":0.523250689344295,"d":"0.52"},{"v":-0.934425787760527,"d":"-0.93"},{"v":0.0693943617345872,"d":"0.07"},{"v":0.573888593466359,"d":"0.57"},"down","no"]
["MSTRG.6242","ANKRD11","ENST00000562275;ENST00000301030;ENST00000567736;ENST00000564553;ENST00000378332;ENST00000566973;ENST00000613312;ENST00000566858;ENST00000567699;ENST00000378330;ENST00000623388;ENST00000568512;ENST00000562816;ENST00000568100;ENST00000330736;ENST00000562194","GO:0005634(nucleus);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0005886(plasma membrane);GO:0042475(odontogenesis of dentin-containing tooth);GO:0048705(skeletal system morphogenesis);GO:0060325(face morphogenesis);GO:0001701(in utero embryonic development);GO:0001894(tissue homeostasis);GO:0035264(multicellular organism growth);GO:0060323(head morphogenesis);GO:0060348(bone development);GO:0060348(bone development)","NA","NA","NA","ankyrin repeat domain 11 [Source:HGNC Symbol;Acc:HGNC:21316]",{"v":5.40511849064842,"d":"5.41"},{"v":1.94414938722049,"d":"1.94"},{"v":2.7801971011991,"d":"2.78"},{"v":1.47518716598568,"d":"1.48"},{"v":0.0694905595842194,"d":"0.07"},{"v":0.573888593466359,"d":"0.57"},"up","no"]
["ENSG00000104517","UBR5","ENST00000220959;ENST00000520539;ENST00000521922;ENST00000519365;ENST00000518205;ENST00000521767;ENST00000521312;ENST00000517465;ENST00000520898;ENST00000518145;ENST00000522327","GO:0003723(RNA binding);GO:0008270(zinc ion binding);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0016740(transferase activity);GO:0016567(protein ubiquitination);GO:0004842(ubiquitin-protein transferase activity);GO:0043130(ubiquitin binding);GO:0005634(nucleus);GO:0090263(positive regulation of canonical Wnt signaling pathway);GO:0016020(membrane);GO:0046872(metal ion binding);GO:0005515(protein binding);GO:0006281(DNA repair);GO:0006974(cellular response to DNA damage stimulus);GO:0043234(protein complex);GO:0008283(cell proliferation);GO:0006511(ubiquitin-dependent protein catabolic process);GO:0000209(protein polyubiquitination);GO:0034450(ubiquitin-ubiquitin ligase activity);GO:0010628(positive regulation of gene expression);GO:0033160(positive regulation of protein import into nucleus, translocation);GO:0035413(positive regulation of catenin import into nucleus);GO:0050847(progesterone receptor signaling pathway);GO:1901315(negative regulation of histone H2A K63-linked ubiquitination);GO:2000780(negative regulation of double-strand break repair);GO:0048471(perinuclear region of cytoplasm);GO:0048471(perinuclear region of cytoplasm)","04120(Ubiquitin mediated proteolysis);04120(Ubiquitin mediated proteolysis)","K10593","EC:2.3.2.26","ubiquitin protein ligase E3 component n-recognin 5 [Source:HGNC Symbol;Acc:HGNC:16806]",{"v":7.225784334658,"d":"7.23"},{"v":2.60082677883072,"d":"2.60"},{"v":2.77826435557795,"d":"2.78"},{"v":1.47418388021784,"d":"1.47"},{"v":0.0695909237311947,"d":"0.07"},{"v":0.573888593466359,"d":"0.57"},"up","no"]
["MSTRG.13945","LRRC4","ENST00000249363;ENST00000478726;ENST00000476782","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0030054(cell junction);GO:0045202(synapse);GO:0045211(postsynaptic membrane);GO:0005737(cytoplasm);GO:0004860(protein kinase inhibitor activity);GO:0006469(negative regulation of protein kinase activity);GO:0019221(cytokine-mediated signaling pathway);GO:0046426(negative regulation of JAK-STAT cascade);GO:0050807(regulation of synapse organization);GO:0050808(synapse organization);GO:0097119(postsynaptic density protein 95 clustering);GO:0043197(dendritic spine);GO:0044309(neuron spine);GO:0060076(excitatory synapse);GO:0060076(excitatory synapse)","04514(Cell adhesion molecules (CAMs));04360(Axon guidance);04360(Axon guidance)","K16351","NA","leucine rich repeat containing 4 [Source:HGNC Symbol;Acc:HGNC:15586]",{"v":8.47070538726462,"d":"8.47"},{"v":3.04452451759167,"d":"3.04"},{"v":2.78227530713573,"d":"2.78"},{"v":1.47626518213322,"d":"1.48"},{"v":0.0696237269969262,"d":"0.07"},{"v":0.573888593466359,"d":"0.57"},"up","no"]
["ENSG00000089154","GCN1","ENST00000300648;ENST00000547369;ENST00000551549;ENST00000551920;ENST00000548821;ENST00000550471;ENST00000548132;ENST00000549815","GO:0003723(RNA binding);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005829(cytosol);GO:0005840(ribosome);GO:0045859(regulation of protein kinase activity);GO:0006417(regulation of translation);GO:0019901(protein kinase binding);GO:0043022(ribosome binding);GO:0019887(protein kinase regulator activity);GO:0033554(cellular response to stress);GO:0045296(cadherin binding);GO:0034198(cellular response to amino acid starvation);GO:0005844(polysome);GO:0008135(translation factor activity, RNA binding);GO:0006412(translation);GO:1990253(cellular response to leucine starvation);GO:0033674(positive regulation of kinase activity);GO:0036003(positive regulation of transcription from RNA polymerase II promoter in response to stress);GO:0036003(positive regulation of transcription from RNA polymerase II promoter in response to stress)","NA","NA","NA","GCN1, eIF2 alpha kinase activator homolog [Source:HGNC Symbol;Acc:HGNC:4199]",{"v":7.66124173555003,"d":"7.66"},{"v":2.76063171079345,"d":"2.76"},{"v":2.77517703850039,"d":"2.78"},{"v":1.47257980909141,"d":"1.47"},{"v":0.0698035923209053,"d":"0.07"},{"v":0.573888593466359,"d":"0.57"},"up","no"]
["MSTRG.8125","CLC","MSTRG.8125.3;MSTRG.8125.1;ENST00000221804","GO:0005737(cytoplasm);GO:0030246(carbohydrate binding);GO:0005829(cytosol);GO:0042802(identical protein binding);GO:0005515(protein binding);GO:0002724(regulation of T cell cytokine production);GO:0007275(multicellular organism development);GO:0097153(cysteine-type endopeptidase activity involved in apoptotic process);GO:0070231(T cell apoptotic process);GO:0002667(regulation of T cell anergy);GO:0046006(regulation of activated T cell proliferation)","NA","NA","NA","Charcot-Leyden crystal galectin [Source:HGNC Symbol;Acc:HGNC:2014]",{"v":17.5042249063444,"d":"17.50"},{"v":33.4841651973817,"d":"33.48"},{"v":0.522761275461428,"d":"0.52"},{"v":-0.935775820182787,"d":"-0.94"},{"v":0.069837147747548,"d":"0.07"},{"v":0.573888593466359,"d":"0.57"},"down","no"]
["MSTRG.5711","RPS15A;ARL6IP1;AC138811.2","ENST00000576008;ENST00000569365;ENST00000565420;ENST00000322989;ENST00000562935;ENST00000569083;ENST00000573554;ENST00000304414;ENST00000563390;ENST00000567078;ENST00000574723;ENST00000562819;ENST00000563861;ENST00000567969;ENST00000575669;ENST00000563579;ENST00000562234;ENST00000569976;ENST00000576436;ENST00000566391","GO:0003723(RNA binding);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0006412(translation);GO:0030529(intracellular ribonucleoprotein complex);GO:0003735(structural constituent of ribosome);GO:0005840(ribosome);GO:0022627(cytosolic small ribosomal subunit);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0009615(response to virus);GO:0031012(extracellular matrix);GO:0005739(mitochondrion);GO:0005515(protein binding);GO:0008284(positive regulation of cell proliferation);GO:0006413(translational initiation);GO:0006364(rRNA processing);GO:0045787(positive regulation of cell cycle);GO:0000184(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay);GO:0019083(viral transcription);GO:0006614(SRP-dependent cotranslational protein targeting to membrane);GO:0016021(integral component of membrane);GO:0002038(positive regulation of L-glutamate transport);GO:0006613(cotranslational protein targeting to membrane);GO:0005783(endoplasmic reticulum);GO:0005784(Sec61 translocon complex);GO:0005789(endoplasmic reticulum membrane);GO:0006915(apoptotic process);GO:0042802(identical protein binding);GO:0012505(endomembrane system);GO:0030176(integral component of endoplasmic reticulum membrane);GO:0043066(negative regulation of apoptotic process);GO:0043154(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process);GO:0071787(endoplasmic reticulum tubular network formation);GO:1990809(endoplasmic reticulum tubular network membrane organization);GO:1990809(endoplasmic reticulum tubular network membrane organization)","03010(Ribosome);03010(Ribosome)","K02957","NA","ribosomal protein S15a [Source:HGNC Symbol;Acc:HGNC:10389];ADP ribosylation factor like GTPase 6 interacting protein 1 [Source:HGNC Symbol;Acc:HGNC:697]",{"v":39.3373199188014,"d":"39.34"},{"v":75.0426939353311,"d":"75.04"},{"v":0.524199197228991,"d":"0.52"},{"v":-0.93181295059654,"d":"-0.93"},{"v":0.0698664003913605,"d":"0.07"},{"v":0.573888593466359,"d":"0.57"},"down","no"]
["MSTRG.9751","ZHX3","ENST00000432768;ENST00000559296;ENST00000441102;ENST00000309060;ENST00000559234;ENST00000561291;ENST00000421422;ENST00000560361;ENST00000560364","GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0003677(DNA binding);GO:0003676(nucleic acid binding);GO:0046872(metal ion binding);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0042803(protein homodimerization activity);GO:0005515(protein binding);GO:0030154(cell differentiation);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0003714(transcription corepressor activity);GO:0045892(negative regulation of transcription, DNA-templated);GO:0046982(protein heterodimerization activity);GO:0045669(positive regulation of osteoblast differentiation);GO:0000977(RNA polymerase II regulatory region sequence-specific DNA binding);GO:0000977(RNA polymerase II regulatory region sequence-specific DNA binding)","NA","NA","NA","zinc fingers and homeoboxes 3 [Source:HGNC Symbol;Acc:HGNC:15935]",{"v":0.438086157473539,"d":"0.44"},{"v":0.153809737544101,"d":"0.15"},{"v":2.84823421760231,"d":"2.85"},{"v":1.51006778769461,"d":"1.51"},{"v":0.0699227683708255,"d":"0.07"},{"v":0.573888593466359,"d":"0.57"},"up","no"]
["MSTRG.11568","KLF3","ENST00000261438;ENST00000482150;ENST00000514033","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0005654(nucleoplasm);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0000977(RNA polymerase II regulatory region sequence-specific DNA binding);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:1901653(cellular response to peptide);GO:0007275(multicellular organism development);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding)","05202(Transcriptional misregulation in cancers);05202(Transcriptional misregulation in cancers)","K15605","NA","Kruppel like factor 3 [Source:HGNC Symbol;Acc:HGNC:16516]",{"v":7.73741153374623,"d":"7.74"},{"v":2.78684886310942,"d":"2.79"},{"v":2.77640156097781,"d":"2.78"},{"v":1.47321624519787,"d":"1.47"},{"v":0.0699751538273023,"d":"0.07"},{"v":0.573888593466359,"d":"0.57"},"up","no"]
["ENSG00000177374","HIC1","ENST00000399849;ENST00000574370;ENST00000619757;ENST00000576444","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0005515(protein binding);GO:0007275(multicellular organism development);GO:0016055(Wnt signaling pathway);GO:0030178(negative regulation of Wnt signaling pathway);GO:0043565(sequence-specific DNA binding);GO:0000785(chromatin);GO:0001227(transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding);GO:0042826(histone deacetylase binding);GO:0043517(positive regulation of DNA damage response, signal transduction by p53 class mediator);GO:0008630(intrinsic apoptotic signaling pathway in response to DNA damage);GO:0008630(intrinsic apoptotic signaling pathway in response to DNA damage)","NA","NA","NA","HIC ZBTB transcriptional repressor 1 [Source:HGNC Symbol;Acc:HGNC:4909]",{"v":0.390709111371485,"d":"0.39"},{"v":0.134558930069068,"d":"0.13"},{"v":2.90362825544865,"d":"2.90"},{"v":1.53785676037542,"d":"1.54"},{"v":0.0700177933470282,"d":"0.07"},{"v":0.573888593466359,"d":"0.57"},"up","no"]
["ENSG00000204959","ARHGEF34P","ENST00000483587","NA","NA","NA","NA","Rho guanine nucleotide exchange factor 34, pseudogene [Source:HGNC Symbol;Acc:HGNC:38086]",{"v":0.627953,"d":"0.63"},{"v":0.215937,"d":"0.22"},{"v":2.90803799256265,"d":"2.91"},{"v":1.54004611771819,"d":"1.54"},{"v":0.0700376754239649,"d":"0.07"},{"v":0.573888593466359,"d":"0.57"},"up","no"]
["MSTRG.14739","NUDT2","ENST00000346365;ENST00000618590;ENST00000379158","GO:0000166(nucleotide binding);GO:0016787(hydrolase activity);GO:0005525(GTP binding);GO:0005515(protein binding);GO:0006915(apoptotic process);GO:0005759(mitochondrial matrix);GO:0006139(nucleobase-containing compound metabolic process);GO:0034599(cellular response to oxidative stress);GO:0004081(bis(5'-nucleosyl)-tetraphosphatase (asymmetrical) activity);GO:0008796(bis(5'-nucleosyl)-tetraphosphatase activity);GO:0008803(bis(5'-nucleosyl)-tetraphosphatase (symmetrical) activity);GO:0005739(mitochondrion);GO:0005739(mitochondrion)","00230(Purine metabolism);00240(Pyrimidine metabolism);00240(Pyrimidine metabolism)","K01518","EC:3.6.1.17","nudix hydrolase 2 [Source:HGNC Symbol;Acc:HGNC:8049]",{"v":5.01351281860465,"d":"5.01"},{"v":9.62421943255814,"d":"9.62"},{"v":0.52092669475555,"d":"0.52"},{"v":-0.940847725365162,"d":"-0.94"},{"v":0.0700846634476794,"d":"0.07"},{"v":0.573888593466359,"d":"0.57"},"down","no"]
["MSTRG.10934","IP6K1","ENST00000395238;ENST00000321599;ENST00000468463;ENST00000495798;ENST00000479464","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0005829(cytosol);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0001650(fibrillar center);GO:0008440(inositol-1,4,5-trisphosphate 3-kinase activity);GO:0005515(protein binding);GO:0005654(nucleoplasm);GO:0043647(inositol phosphate metabolic process);GO:0000828(inositol hexakisphosphate kinase activity);GO:0000829(inositol heptakisphosphate kinase activity);GO:0000832(inositol hexakisphosphate 5-kinase activity);GO:0052723(inositol hexakisphosphate 1-kinase activity);GO:0052724(inositol hexakisphosphate 3-kinase activity);GO:0046854(phosphatidylinositol phosphorylation);GO:0000827(inositol-1,3,4,5,6-pentakisphosphate kinase activity);GO:0052836(inositol 5-diphosphate pentakisphosphate 5-kinase activity);GO:0052839(inositol diphosphate tetrakisphosphate kinase activity);GO:0052839(inositol diphosphate tetrakisphosphate kinase activity)","04070(Phosphatidylinositol signaling system);04070(Phosphatidylinositol signaling system)","K07756","EC:2.7.4.21","inositol hexakisphosphate kinase 1 [Source:HGNC Symbol;Acc:HGNC:18360]",{"v":4.95402631461539,"d":"4.95"},{"v":9.4617446325,"d":"9.46"},{"v":0.523584868016717,"d":"0.52"},{"v":-0.933504691937101,"d":"-0.93"},{"v":0.070103234377187,"d":"0.07"},{"v":0.573888593466359,"d":"0.57"},"down","no"]
["ENSG00000111424","VDR","ENST00000229022;ENST00000548664;ENST00000549336;ENST00000546653;ENST00000547065;ENST00000550314","GO:0008285(negative regulation of cell proliferation);GO:0005634(nucleus);GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0005654(nucleoplasm);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0043565(sequence-specific DNA binding);GO:0005515(protein binding);GO:0003707(steroid hormone receptor activity);GO:0043401(steroid hormone mediated signaling pathway);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0010628(positive regulation of gene expression);GO:0008434(calcitriol receptor activity);GO:0070561(vitamin D receptor signaling pathway);GO:0007165(signal transduction);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0006367(transcription initiation from RNA polymerase II promoter);GO:0090575(RNA polymerase II transcription factor complex);GO:0043235(receptor complex);GO:0010980(positive regulation of vitamin D 24-hydroxylase activity);GO:0046697(decidualization);GO:0045618(positive regulation of keratinocyte differentiation);GO:0045892(negative regulation of transcription, DNA-templated);GO:0070644(vitamin D response element binding);GO:0038186(lithocholic acid receptor activity);GO:0046965(retinoid X receptor binding);GO:1902098(calcitriol binding);GO:1902121(lithocholic acid binding);GO:0000902(cell morphogenesis);GO:0010839(negative regulation of keratinocyte proliferation);GO:0038183(bile acid signaling pathway);GO:0060558(regulation of calcidiol 1-monooxygenase activity);GO:0004879(RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding);GO:0001501(skeletal system development);GO:0006816(calcium ion transport);GO:0006874(cellular calcium ion homeostasis);GO:0007275(multicellular organism development);GO:0007595(lactation);GO:0009887(animal organ morphogenesis);GO:0050892(intestinal absorption);GO:0060058(positive regulation of apoptotic process involved in mammary gland involution);GO:0060745(mammary gland branching involved in pregnancy);GO:0060745(mammary gland branching involved in pregnancy)","04978(Mineral absorption);04961(Endocrine and other factor-regulated calcium reabsorption);05152(Tuberculosis);05152(Tuberculosis)","K08539","NA","vitamin D receptor [Source:HGNC Symbol;Acc:HGNC:12679]",{"v":3.22460690253789,"d":"3.22"},{"v":1.15265276154388,"d":"1.15"},{"v":2.79755274972734,"d":"2.80"},{"v":1.48416533443762,"d":"1.48"},{"v":0.0701321142034229,"d":"0.07"},{"v":0.573888593466359,"d":"0.57"},"up","no"]
["ENSG00000227827","AC138969.2","ENST00000532739","NA","NA","NA","NA",null,{"v":0.518902,"d":"0.52"},{"v":0.183191,"d":"0.18"},{"v":2.83257365263577,"d":"2.83"},{"v":1.50211346951831,"d":"1.50"},{"v":0.0701883351463778,"d":"0.07"},{"v":0.573888593466359,"d":"0.57"},"up","no"]
["MSTRG.4651","RPL3P4","MSTRG.4651.2;MSTRG.4651.1","NA","NA","NA","NA",null,{"v":81.7687193783069,"d":"81.77"},{"v":155.894180153439,"d":"155.89"},{"v":0.524514252538651,"d":"0.52"},{"v":-0.93094611943951,"d":"-0.93"},{"v":0.0701938830567034,"d":"0.07"},{"v":0.573888593466359,"d":"0.57"},"down","no"]
["MSTRG.6849","IFI35","ENST00000246911;ENST00000438323;ENST00000415816;ENST00000546325;ENST00000396722;ENST00000538473;ENST00000536969;ENST00000534876","GO:0005634(nucleus);GO:0005515(protein binding);GO:0005829(cytosol);GO:0060337(type I interferon signaling pathway);GO:0060337(type I interferon signaling pathway)","NA","NA","NA","interferon induced protein 35 [Source:HGNC Symbol;Acc:HGNC:5399]",{"v":7.5849737308667,"d":"7.58"},{"v":14.5145799214394,"d":"14.51"},{"v":0.522576180083791,"d":"0.52"},{"v":-0.936286729238578,"d":"-0.94"},{"v":0.0702186387495545,"d":"0.07"},{"v":0.573888593466359,"d":"0.57"},"down","no"]
["ENSG00000205746","AC126755.1","ENST00000525846;ENST00000433020;ENST00000535716;ENST00000539740;ENST00000545152","NA","NA","NA","NA",null,{"v":1.73792289329806,"d":"1.74"},{"v":0.622042957084068,"d":"0.62"},{"v":2.79389529855763,"d":"2.79"},{"v":1.48227795665217,"d":"1.48"},{"v":0.0702226548967274,"d":"0.07"},{"v":0.573888593466359,"d":"0.57"},"up","no"]
["MSTRG.10079","SUMO3","ENST00000332859;ENST00000466861;ENST00000397898;ENST00000411651;ENST00000479153;ENST00000397893","GO:0016925(protein sumoylation);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005515(protein binding);GO:0005654(nucleoplasm);GO:0070062(extracellular exosome);GO:0016605(PML body);GO:0019899(enzyme binding);GO:0070911(global genome nucleotide-excision repair);GO:0031386(protein tag);GO:0043392(negative regulation of DNA binding);GO:0000776(kinetochore);GO:0000776(kinetochore)","03013(RNA transport);05418(Fluid shear stress and atherosclerosis);05418(Fluid shear stress and atherosclerosis)","K12160","NA","small ubiquitin-like modifier 3 [Source:HGNC Symbol;Acc:HGNC:11124]",{"v":11.2163415574671,"d":"11.22"},{"v":21.3996403912884,"d":"21.40"},{"v":0.524136917834992,"d":"0.52"},{"v":-0.931984365416054,"d":"-0.93"},{"v":0.0703168924294874,"d":"0.07"},{"v":0.573997257480487,"d":"0.57"},"down","no"]
["MSTRG.15486","BCAP31","ENST00000345046;ENST00000458587;ENST00000429550;ENST00000416815;ENST00000430088;ENST00000468947;ENST00000442093;ENST00000423827","GO:0005739(mitochondrion);GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0006886(intracellular protein transport);GO:0015031(protein transport);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005515(protein binding);GO:0006915(apoptotic process);GO:0016192(vesicle-mediated transport);GO:0005887(integral component of plasma membrane);GO:0005829(cytosol);GO:0006888(ER to Golgi vesicle-mediated transport);GO:0097194(execution phase of apoptosis);GO:2001244(positive regulation of intrinsic apoptotic signaling pathway);GO:0007204(positive regulation of cytosolic calcium ion concentration);GO:0005811(lipid particle);GO:0043280(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process);GO:0033116(endoplasmic reticulum-Golgi intermediate compartment membrane);GO:0002474(antigen processing and presentation of peptide antigen via MHC class I);GO:0071556(integral component of lumenal side of endoplasmic reticulum membrane);GO:1903071(positive regulation of ER-associated ubiquitin-dependent protein catabolic process);GO:0035584(calcium-mediated signaling using intracellular calcium source);GO:0032471(negative regulation of endoplasmic reticulum calcium ion concentration);GO:0051561(positive regulation of mitochondrial calcium ion concentration);GO:0005784(Sec61 translocon complex);GO:0070973(protein localization to endoplasmic reticulum exit site);GO:1904154(positive regulation of retrograde protein transport, ER to cytosol);GO:0097038(perinuclear endoplasmic reticulum);GO:0032403(protein complex binding);GO:0042288(MHC class I protein binding);GO:0007283(spermatogenesis);GO:0000139(Golgi membrane);GO:0030136(clathrin-coated vesicle);GO:0032580(Golgi cisterna membrane);GO:0032580(Golgi cisterna membrane)","04141(Protein processing in endoplasmic reticulum);05165(Human papillomavirus infection);05165(Human papillomavirus infection)","K14009","NA","B-cell receptor associated protein 31 [Source:HGNC Symbol;Acc:HGNC:16695]",{"v":16.9379078151677,"d":"16.94"},{"v":32.2925749333079,"d":"32.29"},{"v":0.524514005159039,"d":"0.52"},{"v":-0.930946799866062,"d":"-0.93"},{"v":0.0703348055967221,"d":"0.07"},{"v":0.573997257480487,"d":"0.57"},"down","no"]
["MSTRG.1252","SMG7","ENST00000515829;ENST00000347615;ENST00000444547;ENST00000440812;ENST00000508461;ENST00000367537;ENST00000493045;ENST00000507691;ENST00000502375;ENST00000507469;ENST00000419169;ENST00000507406","GO:0005829(cytosol);GO:0045111(intermediate filament cytoskeleton);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005515(protein binding);GO:0090501(RNA phosphodiester bond hydrolysis);GO:0000184(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay);GO:0042162(telomeric DNA binding);GO:0004540(ribonuclease activity);GO:0043021(ribonucleoprotein complex binding);GO:0051721(protein phosphatase 2A binding);GO:0006406(mRNA export from nucleus);GO:0035303(regulation of dephosphorylation);GO:0043487(regulation of RNA stability);GO:0070034(telomerase RNA binding);GO:0007004(telomere maintenance via telomerase);GO:0005697(telomerase holoenzyme complex);GO:0005697(telomerase holoenzyme complex)","03015(mRNA surveillance pathway);03015(mRNA surveillance pathway)","K14409","NA","SMG7, nonsense mediated mRNA decay factor [Source:HGNC Symbol;Acc:HGNC:16792]",{"v":9.24211445869905,"d":"9.24"},{"v":3.33311957965613,"d":"3.33"},{"v":2.77281214724752,"d":"2.77"},{"v":1.4713498798413,"d":"1.47"},{"v":0.0705125154613942,"d":"0.07"},{"v":0.574878534232759,"d":"0.57"},"up","no"]
["MSTRG.11558","DTHD1","ENST00000639862;ENST00000456874;ENST00000503528;ENST00000507598;ENST00000357504","GO:0007165(signal transduction);GO:0007165(signal transduction)","NA","NA","NA","death domain containing 1 [Source:HGNC Symbol;Acc:HGNC:37261]",{"v":0.997129144713421,"d":"1.00"},{"v":0.355070471342115,"d":"0.36"},{"v":2.8082570227381,"d":"2.81"},{"v":1.48967498281496,"d":"1.49"},{"v":0.0705569306221463,"d":"0.07"},{"v":0.574878534232759,"d":"0.57"},"up","no"]
["MSTRG.5570","ELOB","ENST00000409906;ENST00000409477;ENST00000262306;ENST00000572954;ENST00000494946","GO:0005634(nucleus);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0016567(protein ubiquitination);GO:0005515(protein binding);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0043687(post-translational protein modification);GO:0061418(regulation of transcription from RNA polymerase II promoter in response to hypoxia);GO:0070449(elongin complex);GO:0031625(ubiquitin protein ligase binding);GO:0006366(transcription from RNA polymerase II promoter);GO:0006368(transcription elongation from RNA polymerase II promoter);GO:0006461(protein complex assembly);GO:0031466(Cul5-RING ubiquitin ligase complex);GO:0030891(VCB complex);GO:0031462(Cul2-RING ubiquitin ligase complex);GO:0003746(translation elongation factor activity);GO:0006414(translational elongation);GO:0006414(translational elongation)","04120(Ubiquitin mediated proteolysis);04066(HIF-1 signaling pathway);05200(Pathways in cancer);05211(Renal cell carcinoma);05211(Renal cell carcinoma)","K03873","NA","elongin B [Source:HGNC Symbol;Acc:HGNC:11619]",{"v":27.2663516941489,"d":"27.27"},{"v":51.9967596214539,"d":"52.00"},{"v":0.524385594268816,"d":"0.52"},{"v":-0.931300041979123,"d":"-0.93"},{"v":0.0705926803407921,"d":"0.07"},{"v":0.574878534232759,"d":"0.57"},"down","no"]
["MSTRG.8896","CD8B","ENST00000390655;ENST00000331469;ENST00000393761;ENST00000393759;ENST00000431506","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005886(plasma membrane);GO:0005576(extracellular region);GO:0006955(immune response);GO:0002376(immune system process);GO:0002250(adaptive immune response);GO:0050776(regulation of immune response);GO:0005515(protein binding);GO:0005887(integral component of plasma membrane);GO:0042110(T cell activation);GO:0007169(transmembrane receptor protein tyrosine kinase signaling pathway);GO:0042288(MHC class I protein binding);GO:0050690(regulation of defense response to virus by virus);GO:0015026(coreceptor activity);GO:0031901(early endosome membrane);GO:0042101(T cell receptor complex);GO:0009897(external side of plasma membrane);GO:0009986(cell surface);GO:0009986(cell surface)","04514(Cell adhesion molecules (CAMs));04640(Hematopoietic cell lineage);04612(Antigen processing and presentation);04660(T cell receptor signaling pathway);05340(Primary immunodeficiency);05340(Primary immunodeficiency)","K06459","NA","CD8b molecule [Source:HGNC Symbol;Acc:HGNC:1707]",{"v":9.09497505579399,"d":"9.09"},{"v":17.3605867972103,"d":"17.36"},{"v":0.523886384834381,"d":"0.52"},{"v":-0.932674126270655,"d":"-0.93"},{"v":0.07064080499011,"d":"0.07"},{"v":0.574878534232759,"d":"0.57"},"down","no"]
["MSTRG.4000","RB1","ENST00000267163;ENST00000525036;ENST00000484879","GO:0003674(molecular_function);GO:0008150(biological_process);GO:0005575(cellular_component);GO:0043433(negative regulation of sequence-specific DNA binding transcription factor activity);GO:2000134(negative regulation of G1/S transition of mitotic cell cycle);GO:0005634(nucleus);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0016569(covalent chromatin modification);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0003677(DNA binding);GO:0008134(transcription factor binding);GO:0006915(apoptotic process);GO:0005515(protein binding);GO:0045892(negative regulation of transcription, DNA-templated);GO:0007049(cell cycle);GO:0051726(regulation of cell cycle);GO:0008285(negative regulation of cell proliferation);GO:0003713(transcription coactivator activity);GO:0045893(positive regulation of transcription, DNA-templated);GO:0001102(RNA polymerase II activating transcription factor binding);GO:0019899(enzyme binding);GO:0000082(G1/S transition of mitotic cell cycle);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0001558(regulation of cell growth);GO:0001894(tissue homeostasis);GO:0007050(cell cycle arrest);GO:0010629(negative regulation of gene expression);GO:0030182(neuron differentiation);GO:0031175(neuron projection development);GO:0034349(glial cell apoptotic process);GO:0035914(skeletal muscle cell differentiation);GO:0042551(neuron maturation);GO:0043353(enucleate erythrocyte differentiation);GO:0045651(positive regulation of macrophage differentiation);GO:0045786(negative regulation of cell cycle);GO:0045879(negative regulation of smoothened signaling pathway);GO:0045930(negative regulation of mitotic cell cycle);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0048565(digestive tract development);GO:0048667(cell morphogenesis involved in neuron differentiation);GO:0050680(negative regulation of epithelial cell proliferation);GO:0051146(striated muscle cell differentiation);GO:0051301(cell division);GO:0051402(neuron apoptotic process);GO:0071466(cellular response to xenobiotic stimulus);GO:0071930(negative regulation of transcription involved in G1/S transition of mitotic cell cycle);GO:0097284(hepatocyte apoptotic process);GO:0005667(transcription factor complex);GO:0005819(spindle);GO:0035189(Rb-E2F complex);GO:0042802(identical protein binding);GO:0001047(core promoter binding);GO:0005654(nucleoplasm);GO:0016032(viral process);GO:0031625(ubiquitin protein ligase binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0016605(PML body);GO:0030521(androgen receptor signaling pathway);GO:0006338(chromatin remodeling);GO:0016514(SWI/SNF complex);GO:0006469(negative regulation of protein kinase activity);GO:0000083(regulation of transcription involved in G1/S transition of mitotic cell cycle);GO:0007093(mitotic cell cycle checkpoint);GO:0000075(cell cycle checkpoint);GO:0051219(phosphoprotein binding);GO:0019900(kinase binding);GO:0050681(androgen receptor binding);GO:0008024(cyclin/CDK positive transcription elongation factor complex);GO:0000785(chromatin);GO:0097718(disordered domain specific binding);GO:0007265(Ras protein signal transduction);GO:0061676(importin-alpha family protein binding);GO:0007070(negative regulation of transcription from RNA polymerase II promoter during mitotic cell cycle);GO:0007346(regulation of mitotic cell cycle);GO:0031134(sister chromatid biorientation);GO:0034088(maintenance of mitotic sister chromatid cohesion);GO:0043550(regulation of lipid kinase activity);GO:0045445(myoblast differentiation);GO:0045842(positive regulation of mitotic metaphase/anaphase transition);GO:0071459(protein localization to chromosome, centromeric region);GO:0071922(regulation of cohesin loading);GO:0090230(regulation of centromere complex assembly);GO:2000679(positive regulation of transcription regulatory region DNA binding);GO:2000679(positive regulation of transcription regulatory region DNA binding)","04110(Cell cycle);04218(Cellular senescence);05200(Pathways in cancer);05203(Viral carcinogenesis);05212(Pancreatic cancer);05225(Hepatocellular carcinoma);05226(Gastric cancer);05214(Glioma);05220(Chronic myeloid leukemia);05218(Melanoma);05219(Bladder cancer);05215(Prostate cancer);05224(Breast cancer);05222(Small cell lung cancer);05223(Non-small cell lung cancer);05166(HTLV-I infection);05161(Hepatitis B);05167(Kaposi's sarcoma-associated herpesvirus infection);05169(Epstein-Barr virus infection);05165(Human papillomavirus infection);01522(Endocrine resistance);01522(Endocrine resistance)","K06618","NA","RB transcriptional corepressor 1 [Source:HGNC Symbol;Acc:HGNC:9884]",{"v":5.5825796673691,"d":"5.58"},{"v":2.01039756054466,"d":"2.01"},{"v":2.77685358206297,"d":"2.78"},{"v":1.47345110873739,"d":"1.47"},{"v":0.0706968122960787,"d":"0.07"},{"v":0.574931429407816,"d":"0.57"},"up","no"]
["MSTRG.11695","COPS4","ENST00000264389;ENST00000511653;ENST00000510801;ENST00000506443;ENST00000504274;ENST00000503682;ENST00000511891;ENST00000511708","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016607(nuclear speck);GO:0030054(cell junction);GO:0005515(protein binding);GO:0045202(synapse);GO:0031410(cytoplasmic vesicle);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0008180(COP9 signalosome);GO:0043687(post-translational protein modification);GO:0000338(protein deneddylation);GO:0008021(synaptic vesicle);GO:0006283(transcription-coupled nucleotide-excision repair);GO:0000715(nucleotide-excision repair, DNA damage recognition);GO:0019784(NEDD8-specific protease activity);GO:0019784(NEDD8-specific protease activity)","NA","NA","NA","COP9 signalosome subunit 4 [Source:HGNC Symbol;Acc:HGNC:16702]",{"v":2.92602766573191,"d":"2.93"},{"v":5.60495478996074,"d":"5.60"},{"v":0.522043045016676,"d":"0.52"},{"v":-0.937759325885758,"d":"-0.94"},{"v":0.0707917290045503,"d":"0.07"},{"v":0.575271322836892,"d":"0.58"},"down","no"]
["MSTRG.1420","SRP9","ENST00000366839;ENST00000304786;ENST00000619790;ENST00000366838;ENST00000626563","GO:0003723(RNA binding);GO:0005737(cytoplasm);GO:0030529(intracellular ribonucleoprotein complex);GO:0005515(protein binding);GO:0008312(7S RNA binding);GO:0006614(SRP-dependent cotranslational protein targeting to membrane);GO:0048500(signal recognition particle);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0006616(SRP-dependent cotranslational protein targeting to membrane, translocation);GO:0005786(signal recognition particle, endoplasmic reticulum targeting);GO:0005047(signal recognition particle binding);GO:0005785(signal recognition particle receptor complex);GO:0045900(negative regulation of translational elongation);GO:0045900(negative regulation of translational elongation)","03060(Protein export);03060(Protein export)","K03109","NA","signal recognition particle 9 [Source:HGNC Symbol;Acc:HGNC:11304]",{"v":34.4085817679398,"d":"34.41"},{"v":12.4180871857639,"d":"12.42"},{"v":2.77084395150533,"d":"2.77"},{"v":1.47032546335317,"d":"1.47"},{"v":0.0708376811897663,"d":"0.07"},{"v":0.575271322836892,"d":"0.58"},"up","no"]
["MSTRG.8540","SF3B6","ENST00000233468;ENST00000478050","GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0006397(mRNA processing);GO:0008380(RNA splicing);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0000398(mRNA splicing, via spliceosome);GO:0005684(U2-type spliceosomal complex);GO:0071011(precatalytic spliceosome);GO:0071013(catalytic step 2 spliceosome);GO:0005686(U2 snRNP);GO:0005689(U12-type spliceosomal complex);GO:0001825(blastocyst formation);GO:0001825(blastocyst formation)","03040(Spliceosome);03040(Spliceosome)","K12833","NA","splicing factor 3b subunit 6 [Source:HGNC Symbol;Acc:HGNC:30096]",{"v":13.2549396240602,"d":"13.25"},{"v":25.2536696741855,"d":"25.25"},{"v":0.524871822395361,"d":"0.52"},{"v":-0.929962945960591,"d":"-0.93"},{"v":0.0710794824699493,"d":"0.07"},{"v":0.576558504864941,"d":"0.58"},"down","no"]
["MSTRG.2396","LPXN","ENST00000395074;ENST00000528954;ENST00000530561;ENST00000528489;ENST00000529915","GO:0007155(cell adhesion);GO:1903506(regulation of nucleic acid-templated transcription);GO:0003712(transcription cofactor activity);GO:0005925(focal adhesion);GO:0002102(podosome);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016607(nuclear speck);GO:0016020(membrane);GO:0046872(metal ion binding);GO:0005829(cytosol);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0005886(plasma membrane);GO:0042995(cell projection);GO:0005515(protein binding);GO:0048471(perinuclear region of cytoplasm);GO:0030054(cell junction);GO:0007165(signal transduction);GO:0006461(protein complex assembly);GO:0007162(negative regulation of cell adhesion);GO:0050859(negative regulation of B cell receptor signaling pathway);GO:0033628(regulation of cell adhesion mediated by integrin);GO:0033628(regulation of cell adhesion mediated by integrin)","NA","NA","NA","leupaxin [Source:HGNC Symbol;Acc:HGNC:14061]",{"v":13.9224169513579,"d":"13.92"},{"v":26.518448195379,"d":"26.52"},{"v":0.525008735382335,"d":"0.53"},{"v":-0.929586667560162,"d":"-0.93"},{"v":0.0711184108082654,"d":"0.07"},{"v":0.576558504864941,"d":"0.58"},"down","no"]
["ENSG00000185477","GPRIN3","ENST00000609438","NA","NA","NA","NA","GPRIN family member 3 [Source:HGNC Symbol;Acc:HGNC:27733]",{"v":3.89228611825058,"d":"3.89"},{"v":1.40782056481421,"d":"1.41"},{"v":2.76476009480956,"d":"2.76"},{"v":1.46715429961205,"d":"1.47"},{"v":0.0711679144572409,"d":"0.07"},{"v":0.576558504864941,"d":"0.58"},"up","no"]
["MSTRG.3476","NAB2","ENST00000300131;ENST00000342556;ENST00000554839","GO:0005634(nucleus);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0005515(protein binding);GO:0045892(negative regulation of transcription, DNA-templated);GO:0042802(identical protein binding);GO:0007399(nervous system development);GO:0003714(transcription corepressor activity);GO:0008283(cell proliferation);GO:1902949(positive regulation of tau-protein kinase activity);GO:0008134(transcription factor binding);GO:0001958(endochondral ossification);GO:0014037(Schwann cell differentiation);GO:0016480(negative regulation of transcription from RNA polymerase III promoter);GO:0042552(myelination);GO:0045682(regulation of epidermis development);GO:0045682(regulation of epidermis development)","NA","NA","NA","NGFI-A binding protein 2 [Source:HGNC Symbol;Acc:HGNC:7627]",{"v":1.21699833023256,"d":"1.22"},{"v":2.34114005681063,"d":"2.34"},{"v":0.519831492649139,"d":"0.52"},{"v":-0.943884056474613,"d":"-0.94"},{"v":0.0711947727526329,"d":"0.07"},{"v":0.576558504864941,"d":"0.58"},"down","no"]
["ENSG00000257698","AC084033.3","ENST00000546580;ENST00000553102;ENST00000547492","NA","NA","NA","NA",null,{"v":0.781870967987805,"d":"0.78"},{"v":1.54856718292683,"d":"1.55"},{"v":0.504899610819629,"d":"0.50"},{"v":-0.985931529537973,"d":"-0.99"},{"v":0.071345056823826,"d":"0.07"},{"v":0.57737292327184,"d":"0.58"},"down","no"]
["MSTRG.6221","ZCCHC14","ENST00000268616;ENST00000568020;ENST00000561928","GO:0003676(nucleic acid binding);GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0035091(phosphatidylinositol binding);GO:0035091(phosphatidylinositol binding)","NA","NA","NA","zinc finger CCHC-type containing 14 [Source:HGNC Symbol;Acc:HGNC:24134]",{"v":1.78043027686062,"d":"1.78"},{"v":0.639700175101489,"d":"0.64"},{"v":2.78322618338842,"d":"2.78"},{"v":1.47675815638538,"d":"1.48"},{"v":0.0714383420688345,"d":"0.07"},{"v":0.577725255184802,"d":"0.58"},"up","no"]
["MSTRG.439","NDUFS5","ENST00000372967;ENST00000372969","GO:0016020(membrane);GO:0055114(oxidation-reduction process);GO:0005743(mitochondrial inner membrane);GO:0005739(mitochondrion);GO:0070469(respiratory chain);GO:0005758(mitochondrial intermembrane space);GO:0032981(mitochondrial respiratory chain complex I assembly);GO:0008137(NADH dehydrogenase (ubiquinone) activity);GO:0006120(mitochondrial electron transport, NADH to ubiquinone);GO:0005747(mitochondrial respiratory chain complex I);GO:0005747(mitochondrial respiratory chain complex I)","00190(Oxidative phosphorylation);04723(Retrograde endocannabinoid signaling);05010(Alzheimer's disease);05012(Parkinson's disease);05016(Huntington's disease);04932(Non-alcoholic fatty liver disease (NAFLD));04932(Non-alcoholic fatty liver disease (NAFLD))","K03938","NA","NADH:ubiquinone oxidoreductase subunit S5 [Source:HGNC Symbol;Acc:HGNC:7712]",{"v":31.3486777445255,"d":"31.35"},{"v":59.6620304744525,"d":"59.66"},{"v":0.525437661025451,"d":"0.53"},{"v":-0.928408484770938,"d":"-0.93"},{"v":0.0715075205271962,"d":"0.07"},{"v":0.577882279667591,"d":"0.58"},"down","no"]
["ENSG00000165644","COMTD1","ENST00000372538;ENST00000491270;ENST00000490521;ENST00000470947;ENST00000460899","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0008168(methyltransferase activity);GO:0016740(transferase activity);GO:0032259(methylation);GO:0005515(protein binding);GO:0008171(O-methyltransferase activity);GO:0005739(mitochondrion);GO:0005739(mitochondrion)","NA","NA","NA","catechol-O-methyltransferase domain containing 1 [Source:HGNC Symbol;Acc:HGNC:26309]",{"v":1.40417311582279,"d":"1.40"},{"v":2.70782074113924,"d":"2.71"},{"v":0.518562065239231,"d":"0.52"},{"v":-0.947411423391449,"d":"-0.95"},{"v":0.0716056313879715,"d":"0.07"},{"v":0.578272738044863,"d":"0.58"},"down","no"]
["MSTRG.11478","ATP5I","ENST00000304312;ENST00000515202;ENST00000515116;ENST00000506525;ENST00000505852","GO:0006810(transport);GO:0016020(membrane);GO:0005739(mitochondrion);GO:0005743(mitochondrial inner membrane);GO:0006811(ion transport);GO:0015078(hydrogen ion transmembrane transporter activity);GO:0015992(proton transport);GO:0015986(ATP synthesis coupled proton transport);GO:0016887(ATPase activity);GO:0000276(mitochondrial proton-transporting ATP synthase complex, coupling factor F(o));GO:0006754(ATP biosynthetic process);GO:0022857(transmembrane transporter activity);GO:0042407(cristae formation);GO:0042776(mitochondrial ATP synthesis coupled proton transport);GO:0005753(mitochondrial proton-transporting ATP synthase complex);GO:0045263(proton-transporting ATP synthase complex, coupling factor F(o));GO:0046034(ATP metabolic process);GO:0046034(ATP metabolic process)","00190(Oxidative phosphorylation);00190(Oxidative phosphorylation)","K02129","NA","ATP synthase, H+ transporting, mitochondrial Fo complex subunit E [Source:HGNC Symbol;Acc:HGNC:846]",{"v":9.57531885106383,"d":"9.58"},{"v":18.2855803510638,"d":"18.29"},{"v":0.52365408519871,"d":"0.52"},{"v":-0.933313982290471,"d":"-0.93"},{"v":0.0719689868595989,"d":"0.07"},{"v":0.58076622314619,"d":"0.58"},"down","no"]
["ENSG00000149716","ORAOV1","ENST00000279147;ENST00000535657;ENST00000544096;ENST00000535542;ENST00000355486;ENST00000537324;ENST00000542341;ENST00000542515;ENST00000542470;ENST00000543023;ENST00000539414","GO:0003674(molecular_function);GO:0008150(biological_process);GO:0005575(cellular_component);GO:0031573(intra-S DNA damage checkpoint);GO:0030896(checkpoint clamp complex);GO:0000724(double-strand break repair via homologous recombination);GO:0006289(nucleotide-excision repair);GO:0033314(mitotic DNA replication checkpoint);GO:0044778(meiotic DNA integrity checkpoint);GO:0035861(site of double-strand break);GO:0035861(site of double-strand break)","NA","NA","NA","oral cancer overexpressed 1 [Source:HGNC Symbol;Acc:HGNC:17589]",{"v":1.07865191857215,"d":"1.08"},{"v":0.38378904789126,"d":"0.38"},{"v":2.81053335028405,"d":"2.81"},{"v":1.49084393428801,"d":"1.49"},{"v":0.0720603154856365,"d":"0.07"},{"v":0.58076622314619,"d":"0.58"},"up","no"]
["ENSG00000085644","ZNF213","ENST00000574928;ENST00000396878;ENST00000576863;ENST00000416391;ENST00000572647;ENST00000573771;ENST00000576416","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0005622(intracellular);GO:0005622(intracellular)","NA","NA","NA","zinc finger protein 213 [Source:HGNC Symbol;Acc:HGNC:13005]",{"v":1.96240925547105,"d":"1.96"},{"v":0.704127712401055,"d":"0.70"},{"v":2.78700755688097,"d":"2.79"},{"v":1.47871691426803,"d":"1.48"},{"v":0.0720644215580522,"d":"0.07"},{"v":0.58076622314619,"d":"0.58"},"up","no"]
["MSTRG.12214","LNPEP","ENST00000231368;ENST00000395770;ENST00000474122;ENST00000395784","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0016787(hydrolase activity);GO:0005765(lysosomal membrane);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0008233(peptidase activity);GO:0006508(proteolysis);GO:0005576(extracellular region);GO:0008237(metallopeptidase activity);GO:0004177(aminopeptidase activity);GO:0005829(cytosol);GO:0061024(membrane organization);GO:0007165(signal transduction);GO:0000209(protein polyubiquitination);GO:0005887(integral component of plasma membrane);GO:0007267(cell-cell signaling);GO:0042277(peptide binding);GO:0030659(cytoplasmic vesicle membrane);GO:0007565(female pregnancy);GO:0002480(antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent);GO:0070006(metalloaminopeptidase activity);GO:0008217(regulation of blood pressure);GO:0043171(peptide catabolic process);GO:0031905(early endosome lumen);GO:0005622(intracellular);GO:0030163(protein catabolic process);GO:0060395(SMAD protein signal transduction);GO:0048471(perinuclear region of cytoplasm);GO:0048471(perinuclear region of cytoplasm)","04614(Renin-angiotensin system);04614(Renin-angiotensin system)","K01257","EC:3.4.11.3","leucyl and cystinyl aminopeptidase [Source:HGNC Symbol;Acc:HGNC:6656]",{"v":9.6434970843705,"d":"9.64"},{"v":3.50208789951526,"d":"3.50"},{"v":2.75364221603498,"d":"2.75"},{"v":1.46134112058977,"d":"1.46"},{"v":0.0722397795583509,"d":"0.07"},{"v":0.58143995855128,"d":"0.58"},"up","no"]
["ENSG00000084731","KIF3C","ENST00000264712;ENST00000496378;ENST00000475453;ENST00000455394","GO:0005737(cytoplasm);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0003777(microtubule motor activity);GO:0005856(cytoskeleton);GO:0008017(microtubule binding);GO:0005874(microtubule);GO:0003774(motor activity);GO:0007018(microtubule-based movement);GO:0035735(intraciliary transport involved in cilium assembly);GO:0005929(cilium);GO:0097542(ciliary tip);GO:0005829(cytosol);GO:0006890(retrograde vesicle-mediated transport, Golgi to ER);GO:0072384(organelle transport along microtubule);GO:0016887(ATPase activity);GO:0019886(antigen processing and presentation of exogenous peptide antigen via MHC class II);GO:0005871(kinesin complex);GO:0005871(kinesin complex)","NA","NA","NA","kinesin family member 3C [Source:HGNC Symbol;Acc:HGNC:6321]",{"v":1.4631872940809,"d":"1.46"},{"v":0.524307251600812,"d":"0.52"},{"v":2.79070581155135,"d":"2.79"},{"v":1.480630047519,"d":"1.48"},{"v":0.0722481581150002,"d":"0.07"},{"v":0.58143995855128,"d":"0.58"},"up","no"]
["ENSG00000107362","ABHD17B","ENST00000333421;ENST00000377041","GO:0016020(membrane);GO:0016787(hydrolase activity);GO:0005576(extracellular region);GO:0005576(extracellular region)","NA","NA","NA","abhydrolase domain containing 17B [Source:HGNC Symbol;Acc:HGNC:24278]",{"v":1.42178322068266,"d":"1.42"},{"v":2.73156462791484,"d":"2.73"},{"v":0.520501402805171,"d":"0.52"},{"v":-0.942026043144924,"d":"-0.94"},{"v":0.0722992857141825,"d":"0.07"},{"v":0.581448479916068,"d":"0.58"},"down","no"]
["MSTRG.3096","FOXJ2","ENST00000162391;ENST00000539192;ENST00000428177","GO:0005634(nucleus);GO:0006355(regulation of transcription, DNA-templated);GO:0006366(transcription from RNA polymerase II promoter);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0001650(fibrillar center);GO:0043565(sequence-specific DNA binding);GO:0005515(protein binding);GO:0042802(identical protein binding);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0009653(anatomical structure morphogenesis);GO:0030154(cell differentiation);GO:0001077(transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0001077(transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding)","NA","NA","NA","forkhead box J2 [Source:HGNC Symbol;Acc:HGNC:24818]",{"v":6.15615153859593,"d":"6.16"},{"v":2.23127566407243,"d":"2.23"},{"v":2.75902777846821,"d":"2.76"},{"v":1.46415998211945,"d":"1.46"},{"v":0.072413071359952,"d":"0.07"},{"v":0.581958441476834,"d":"0.58"},"up","no"]
["MSTRG.4144","CHD8","ENST00000557364;ENST00000430710;ENST00000555962;ENST00000556833;ENST00000555301;ENST00000553870;ENST00000553283;ENST00000554384;ENST00000557727;ENST00000555935;ENST00000399982;ENST00000557329;ENST00000553622;ENST00000553651","GO:0005634(nucleus);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0005654(nucleoplasm);GO:0016787(hydrolase activity);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0016569(covalent chromatin modification);GO:0004386(helicase activity);GO:0032508(DNA duplex unwinding);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0043044(ATP-dependent chromatin remodeling);GO:0016055(Wnt signaling pathway);GO:0045893(positive regulation of transcription, DNA-templated);GO:0016817(hydrolase activity, acting on acid anhydrides);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0030178(negative regulation of Wnt signaling pathway);GO:0043234(protein complex);GO:0042393(histone binding);GO:0045892(negative regulation of transcription, DNA-templated);GO:0071339(MLL1 complex);GO:0008013(beta-catenin binding);GO:0007420(brain development);GO:0035064(methylated histone binding);GO:0002039(p53 binding);GO:0060070(canonical Wnt signaling pathway);GO:0008094(DNA-dependent ATPase activity);GO:0090090(negative regulation of canonical Wnt signaling pathway);GO:0003682(chromatin binding);GO:0003678(DNA helicase activity);GO:0045945(positive regulation of transcription from RNA polymerase III promoter);GO:0048565(digestive tract development);GO:0070016(armadillo repeat domain binding);GO:0001701(in utero embryonic development);GO:0043066(negative regulation of apoptotic process);GO:2000270(negative regulation of fibroblast apoptotic process);GO:2000270(negative regulation of fibroblast apoptotic process)","04310(Wnt signaling pathway);04310(Wnt signaling pathway)","K04494","EC:3.6.4.12","chromodomain helicase DNA binding protein 8 [Source:HGNC Symbol;Acc:HGNC:20153]",{"v":10.4285889849709,"d":"10.43"},{"v":3.78442466302014,"d":"3.78"},{"v":2.75566034828883,"d":"2.76"},{"v":1.46239807815952,"d":"1.46"},{"v":0.0725018723760309,"d":"0.07"},{"v":0.581958441476834,"d":"0.58"},"up","no"]
["MSTRG.8853","SUCLG1","ENST00000393868;ENST00000442240;ENST00000484365;ENST00000430989;ENST00000483605;ENST00000487809;ENST00000491123;ENST00000491642;ENST00000488234","GO:0003723(RNA binding);GO:0000166(nucleotide binding);GO:0005829(cytosol);GO:0006099(tricarboxylic acid cycle);GO:0005739(mitochondrion);GO:0003824(catalytic activity);GO:0008152(metabolic process);GO:0005886(plasma membrane);GO:0016874(ligase activity);GO:0048037(cofactor binding);GO:0004775(succinate-CoA ligase (ADP-forming) activity);GO:0004776(succinate-CoA ligase (GDP-forming) activity);GO:0070062(extracellular exosome);GO:0005759(mitochondrial matrix);GO:0005743(mitochondrial inner membrane);GO:0005743(mitochondrial inner membrane)","00020(Citrate cycle (TCA cycle));00640(Propanoate metabolism);00640(Propanoate metabolism)","K01899","EC:6.2.1.4;EC:6.2.1.5","succinate-CoA ligase alpha subunit [Source:HGNC Symbol;Acc:HGNC:11449]",{"v":4.76238247550163,"d":"4.76"},{"v":9.02975197153523,"d":"9.03"},{"v":0.527410109437583,"d":"0.53"},{"v":-0.923002869730234,"d":"-0.92"},{"v":0.0725174976928319,"d":"0.07"},{"v":0.581958441476834,"d":"0.58"},"down","no"]
["MSTRG.14110","TRBV27","ENST00000390399","NA","NA","NA","NA","T-cell receptor beta variable 27 [Source:HGNC Symbol;Acc:HGNC:12208]",{"v":4.313705,"d":"4.31"},{"v":8.415781,"d":"8.42"},{"v":0.512573342866218,"d":"0.51"},{"v":-0.964169643793437,"d":"-0.96"},{"v":0.0725631467543663,"d":"0.07"},{"v":0.581958441476834,"d":"0.58"},"down","no"]
["MSTRG.848","CD160","ENST00000369288;ENST00000616463;ENST00000235933;ENST00000401557;ENST00000584442","GO:0016020(membrane);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0031225(anchored component of membrane);GO:0050776(regulation of immune response);GO:0004872(receptor activity);GO:0007166(cell surface receptor signaling pathway);GO:0008283(cell proliferation);GO:0005102(receptor binding);GO:0006968(cellular defense response);GO:0046658(anchored component of plasma membrane);GO:0032393(MHC class I receptor activity);GO:0016021(integral component of membrane);GO:0050829(defense response to Gram-negative bacterium);GO:0050829(defense response to Gram-negative bacterium)","NA","NA","NA","CD160 molecule [Source:HGNC Symbol;Acc:HGNC:17013]",{"v":2.18588188441199,"d":"2.19"},{"v":4.16825539083354,"d":"4.17"},{"v":0.524411697330012,"d":"0.52"},{"v":-0.931228228756018,"d":"-0.93"},{"v":0.0726226808476629,"d":"0.07"},{"v":0.582033949402284,"d":"0.58"},"down","no"]
["MSTRG.3739","OAS3","ENST00000228928;ENST00000549918;ENST00000546800;ENST00000546973;ENST00000551007;ENST00000548514","GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0016740(transferase activity);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0006955(immune response);GO:0016779(nucleotidyltransferase activity);GO:0005615(extracellular space);GO:0003725(double-stranded RNA binding);GO:0051607(defense response to virus);GO:0002376(immune system process);GO:0045087(innate immune response);GO:0009615(response to virus);GO:0045071(negative regulation of viral genome replication);GO:0006139(nucleobase-containing compound metabolic process);GO:0060333(interferon-gamma-mediated signaling pathway);GO:0060337(type I interferon signaling pathway);GO:0043231(intracellular membrane-bounded organelle);GO:0001730(2'-5'-oligoadenylate synthetase activity);GO:0060700(regulation of ribonuclease activity);GO:0060700(regulation of ribonuclease activity)","04621(NOD-like receptor signaling pathway);05162(Measles);05164(Influenza A);05160(Hepatitis C);05168(Herpes simplex infection);05168(Herpes simplex infection)","K14216","EC:2.7.7.84","2'-5'-oligoadenylate synthetase 3 [Source:HGNC Symbol;Acc:HGNC:8088]",{"v":6.98159029972125,"d":"6.98"},{"v":2.53752220106654,"d":"2.54"},{"v":2.75134156335138,"d":"2.75"},{"v":1.46013525312723,"d":"1.46"},{"v":0.0729150908993306,"d":"0.07"},{"v":0.582135795928719,"d":"0.58"},"up","no"]
["ENSG00000169635","HIC2","ENST00000443632;ENST00000407598;ENST00000407464","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0008022(protein C-terminus binding);GO:0045892(negative regulation of transcription, DNA-templated);GO:0045892(negative regulation of transcription, DNA-templated)","NA","NA","NA","HIC ZBTB transcriptional repressor 2 [Source:HGNC Symbol;Acc:HGNC:18595]",{"v":0.868063899986148,"d":"0.87"},{"v":0.310677237844577,"d":"0.31"},{"v":2.79410202694159,"d":"2.79"},{"v":1.48238470187667,"d":"1.48"},{"v":0.0729219195308097,"d":"0.07"},{"v":0.582135795928719,"d":"0.58"},"up","no"]
["MSTRG.14805","TMEM2","ENST00000377044;ENST00000537329;ENST00000538669;ENST00000474495;ENST00000543165;ENST00000546219;ENST00000396272;ENST00000377057;ENST00000377066;ENST00000377043","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016787(hydrolase activity);GO:0005886(plasma membrane);GO:0008152(metabolic process);GO:0016798(hydrolase activity, acting on glycosyl bonds);GO:0004415(hyalurononglucosaminidase activity);GO:0007275(multicellular organism development);GO:0005509(calcium ion binding);GO:0005887(integral component of plasma membrane);GO:0045296(cadherin binding);GO:0070062(extracellular exosome);GO:0001525(angiogenesis);GO:0030214(hyaluronan catabolic process);GO:1903670(regulation of sprouting angiogenesis);GO:1903670(regulation of sprouting angiogenesis)","NA","NA","NA","transmembrane protein 2 [Source:HGNC Symbol;Acc:HGNC:11869]",{"v":6.7379640507013,"d":"6.74"},{"v":2.44788136405195,"d":"2.45"},{"v":2.75256969134649,"d":"2.75"},{"v":1.46077909134174,"d":"1.46"},{"v":0.0729361957749278,"d":"0.07"},{"v":0.582135795928719,"d":"0.58"},"up","no"]
["MSTRG.14608","ZC3H3","ENST00000262577;ENST00000528401","GO:0006810(transport);GO:0051028(mRNA transport);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0003677(DNA binding);GO:0090502(RNA phosphodiester bond hydrolysis, endonucleolytic);GO:0003723(RNA binding);GO:0003674(molecular_function);GO:0004521(endoribonuclease activity);GO:0005847(mRNA cleavage and polyadenylation specificity factor complex);GO:0006378(mRNA polyadenylation);GO:0016973(poly(A)+ mRNA export from nucleus);GO:0010793(regulation of mRNA export from nucleus);GO:0046332(SMAD binding);GO:0070412(R-SMAD binding);GO:0031124(mRNA 3'-end processing);GO:0032927(positive regulation of activin receptor signaling pathway);GO:0032927(positive regulation of activin receptor signaling pathway)","NA","NA","NA","zinc finger CCCH-type containing 3 [Source:HGNC Symbol;Acc:HGNC:28972]",{"v":5.64361565639239,"d":"5.64"},{"v":2.04372069203967,"d":"2.04"},{"v":2.76144175589863,"d":"2.76"},{"v":1.46542169852527,"d":"1.47"},{"v":0.0729651611811862,"d":"0.07"},{"v":0.582135795928719,"d":"0.58"},"up","no"]
["MSTRG.14593","TRAPPC9","ENST00000438773;ENST00000524162;ENST00000389328;ENST00000634178;ENST00000521700;ENST00000520857;ENST00000519482;ENST00000523777;ENST00000521167","GO:0005737(cytoplasm);GO:0005794(Golgi apparatus);GO:0005783(endoplasmic reticulum);GO:0043547(positive regulation of GTPase activity);GO:0030154(cell differentiation);GO:0000139(Golgi membrane);GO:0005515(protein binding);GO:0005829(cytosol);GO:0017112(Rab guanyl-nucleotide exchange factor activity);GO:0061024(membrane organization);GO:0005802(trans-Golgi network);GO:0048208(COPII vesicle coating);GO:0030008(TRAPP complex);GO:0021987(cerebral cortex development);GO:0030182(neuron differentiation);GO:0051092(positive regulation of NF-kappaB transcription factor activity);GO:0051092(positive regulation of NF-kappaB transcription factor activity)","NA","NA","NA","trafficking protein particle complex 9 [Source:HGNC Symbol;Acc:HGNC:30832]",{"v":3.3578450714387,"d":"3.36"},{"v":1.21517737717931,"d":"1.22"},{"v":2.76325508892618,"d":"2.76"},{"v":1.46636875018575,"d":"1.47"},{"v":0.0729693315674659,"d":"0.07"},{"v":0.582135795928719,"d":"0.58"},"up","no"]
["MSTRG.1331","NUAK2","ENST00000367157","GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0006915(apoptotic process);GO:0000287(magnesium ion binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0035556(intracellular signal transduction);GO:0005515(protein binding);GO:0042149(cellular response to glucose starvation);GO:0016607(nuclear speck);GO:0043066(negative regulation of apoptotic process);GO:0030036(actin cytoskeleton organization)","NA","NA","NA","NUAK family kinase 2 [Source:HGNC Symbol;Acc:HGNC:29558]",{"v":8.086822,"d":"8.09"},{"v":2.934409,"d":"2.93"},{"v":2.7558605497734,"d":"2.76"},{"v":1.46250288759214,"d":"1.46"},{"v":0.0730072721847892,"d":"0.07"},{"v":0.582135795928719,"d":"0.58"},"up","no"]
["MSTRG.13825","POP7","ENST00000303151","GO:0005634(nucleus);GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0005737(cytoplasm);GO:0008033(tRNA processing);GO:0016787(hydrolase activity);GO:0005515(protein binding);GO:0005730(nucleolus);GO:0005654(nucleoplasm);GO:0004526(ribonuclease P activity);GO:0001682(tRNA 5'-leader removal);GO:0090502(RNA phosphodiester bond hydrolysis, endonucleolytic);GO:0000172(ribonuclease MRP complex);GO:0005655(nucleolar ribonuclease P complex);GO:0030681(multimeric ribonuclease P complex);GO:0090501(RNA phosphodiester bond hydrolysis)","03013(RNA transport);03008(Ribosome biogenesis in eukaryotes)","K14527","EC:3.1.26.5","POP7 homolog, ribonuclease P/MRP subunit [Source:HGNC Symbol;Acc:HGNC:19949]",{"v":5.16873713866397,"d":"5.17"},{"v":9.88717839777328,"d":"9.89"},{"v":0.522771708036343,"d":"0.52"},{"v":-0.935747029079431,"d":"-0.94"},{"v":0.0730118235947303,"d":"0.07"},{"v":0.582135795928719,"d":"0.58"},"down","no"]
["ENSG00000131797","CLUHP3","ENST00000532304;ENST00000563678;ENST00000525610;ENST00000431761;ENST00000254109;ENST00000562354;ENST00000411844","NA","NA","NA","NA","clustered mitochondria homolog pseudogene 3 [Source:HGNC Symbol;Acc:HGNC:28447]",{"v":0.70035660978348,"d":"0.70"},{"v":1.34624607714515,"d":"1.35"},{"v":0.52022926690242,"d":"0.52"},{"v":-0.942780530617472,"d":"-0.94"},{"v":0.0730798417446992,"d":"0.07"},{"v":0.582135795928719,"d":"0.58"},"down","no"]
["MSTRG.5695","MARF1","MSTRG.5695.1;ENST00000396368;ENST00000540441;ENST00000551742;ENST00000552771;ENST00000549337;ENST00000551579;ENST00000547936;ENST00000551678;ENST00000549219;ENST00000552553;ENST00000548216;ENST00000551878;ENST00000552535;ENST00000546864","GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0016020(membrane);GO:0005794(Golgi apparatus);GO:0043231(intracellular membrane-bounded organelle);GO:0051321(meiotic cell cycle);GO:0030154(cell differentiation);GO:0005777(peroxisome);GO:0010468(regulation of gene expression);GO:0003674(molecular_function);GO:0010923(negative regulation of phosphatase activity);GO:0048477(oogenesis);GO:0007143(female meiotic nuclear division);GO:0006302(double-strand break repair);GO:0006302(double-strand break repair)","NA","NA","NA","meiosis regulator and mRNA stability factor 1 [Source:HGNC Symbol;Acc:HGNC:29562]",{"v":13.6162015524377,"d":"13.62"},{"v":4.9571978700456,"d":"4.96"},{"v":2.74675369218466,"d":"2.75"},{"v":1.45772754638186,"d":"1.46"},{"v":0.0731651940366074,"d":"0.07"},{"v":0.582135795928719,"d":"0.58"},"up","no"]
["MSTRG.14403","RPL7","ENST00000352983;ENST00000396465;ENST00000435330;MSTRG.14403.3;ENST00000396466;ENST00000487500;ENST00000431653;ENST00000466821;ENST00000396467","GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0006412(translation);GO:0030529(intracellular ribonucleoprotein complex);GO:0005840(ribosome);GO:0005515(protein binding);GO:0003735(structural constituent of ribosome);GO:0005730(nucleolus);GO:0005925(focal adhesion);GO:0006364(rRNA processing);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0042273(ribosomal large subunit biogenesis);GO:0002181(cytoplasmic translation);GO:0006413(translational initiation);GO:0003677(DNA binding);GO:0042803(protein homodimerization activity);GO:0000184(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay);GO:0019083(viral transcription);GO:0006614(SRP-dependent cotranslational protein targeting to membrane);GO:0022625(cytosolic large ribosomal subunit);GO:0003729(mRNA binding);GO:0000463(maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA));GO:0005844(polysome);GO:0005844(polysome)","03010(Ribosome);03010(Ribosome)","K02937","NA","ribosomal protein L7 [Source:HGNC Symbol;Acc:HGNC:10363]",{"v":113.881258249054,"d":"113.88"},{"v":215.040400694874,"d":"215.04"},{"v":0.529580757295197,"d":"0.53"},{"v":-0.917077393171142,"d":"-0.92"},{"v":0.073260522282828,"d":"0.07"},{"v":0.582135795928719,"d":"0.58"},"down","no"]
["MSTRG.1202","PRDX6","ENST00000340385;ENST00000460950;ENST00000470017","GO:0005737(cytoplasm);GO:0005623(cell);GO:0005634(nucleus);GO:0016020(membrane);GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0016787(hydrolase activity);GO:0006629(lipid metabolic process);GO:0016042(lipid catabolic process);GO:0005829(cytosol);GO:0045454(cell redox homeostasis);GO:0005515(protein binding);GO:0003824(catalytic activity);GO:0008152(metabolic process);GO:0048471(perinuclear region of cytoplasm);GO:0005615(extracellular space);GO:0031410(cytoplasmic vesicle);GO:0098869(cellular oxidant detoxification);GO:0004623(phospholipase A2 activity);GO:0005764(lysosome);GO:0005576(extracellular region);GO:0004601(peroxidase activity);GO:0051920(peroxiredoxin activity);GO:0016209(antioxidant activity);GO:0045296(cadherin binding);GO:0070062(extracellular exosome);GO:0043312(neutrophil degranulation);GO:0035578(azurophil granule lumen);GO:0034599(cellular response to oxidative stress);GO:0031625(ubiquitin protein ligase binding);GO:0042803(protein homodimerization activity);GO:0004602(glutathione peroxidase activity);GO:0047499(calcium-independent phospholipase A2 activity);GO:0006979(response to oxidative stress);GO:0042744(hydrogen peroxide catabolic process);GO:0046475(glycerophospholipid catabolic process);GO:0048026(positive regulation of mRNA splicing, via spliceosome);GO:0048026(positive regulation of mRNA splicing, via spliceosome)","NA","NA","NA","peroxiredoxin 6 [Source:HGNC Symbol;Acc:HGNC:16753]",{"v":30.9874473945923,"d":"30.99"},{"v":58.5325629902831,"d":"58.53"},{"v":0.52940527138264,"d":"0.53"},{"v":-0.917555534810886,"d":"-0.92"},{"v":0.0732923701042095,"d":"0.07"},{"v":0.582135795928719,"d":"0.58"},"down","no"]
["MSTRG.9096","SAP130","MSTRG.9096.3;ENST00000450957;ENST00000259235;ENST00000259234","GO:0005634(nucleus);GO:0016607(nuclear speck);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0070822(Sin3-type complex);GO:0070822(Sin3-type complex)","NA","NA","NA","Sin3A associated protein 130 [Source:HGNC Symbol;Acc:HGNC:29813]",{"v":6.00050422913332,"d":"6.00"},{"v":2.17624950468786,"d":"2.18"},{"v":2.75726850997904,"d":"2.76"},{"v":1.46323976758482,"d":"1.46"},{"v":0.0733184076291503,"d":"0.07"},{"v":0.582135795928719,"d":"0.58"},"up","no"]
["MSTRG.9699","ERGIC3","ENST00000348547;ENST00000411577;ENST00000488935;ENST00000438317;ENST00000279052;ENST00000357394;ENST00000461043;ENST00000489071;ENST00000413587;ENST00000482338;ENST00000640748;ENST00000465298;ENST00000447986;ENST00000442139;ENST00000451605;ENST00000488384;ENST00000496172","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005794(Golgi apparatus);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0016192(vesicle-mediated transport);GO:0033116(endoplasmic reticulum-Golgi intermediate compartment membrane);GO:0033116(endoplasmic reticulum-Golgi intermediate compartment membrane)","NA","NA","NA","ERGIC and golgi 3 [Source:HGNC Symbol;Acc:HGNC:15927]",{"v":7.0322669760479,"d":"7.03"},{"v":13.3038602358616,"d":"13.30"},{"v":0.528588458640889,"d":"0.53"},{"v":-0.919783169800673,"d":"-0.92"},{"v":0.0733292229480579,"d":"0.07"},{"v":0.582135795928719,"d":"0.58"},"down","no"]
["MSTRG.292","SLC9A1","ENST00000263980;ENST00000374084;ENST00000374086;ENST00000447808;ENST00000374089","GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0010613(positive regulation of cardiac muscle hypertrophy);GO:0006810(transport);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0055085(transmembrane transport);GO:0005654(nucleoplasm);GO:0005886(plasma membrane);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0006811(ion transport);GO:0015297(antiporter activity);GO:0015299(solute:proton antiporter activity);GO:0015385(sodium:proton antiporter activity);GO:0006812(cation transport);GO:0006814(sodium ion transport);GO:0006885(regulation of pH);GO:0005925(focal adhesion);GO:0005516(calmodulin binding);GO:0005515(protein binding);GO:0070062(extracellular exosome);GO:0048306(calcium-dependent protein binding);GO:0032947(protein complex scaffold);GO:0030027(lamellipodium);GO:0086036(regulation of cardiac muscle cell membrane potential);GO:0051259(protein oligomerization);GO:0030674(protein binding, bridging);GO:0035994(response to muscle stretch);GO:0016477(cell migration);GO:0005887(integral component of plasma membrane);GO:0045121(membrane raft);GO:0030214(hyaluronan catabolic process);GO:0051453(regulation of intracellular pH);GO:0006883(cellular sodium ion homeostasis);GO:0010882(regulation of cardiac muscle contraction by calcium ion signaling);GO:1903281(positive regulation of calcium:sodium antiporter activity);GO:0071872(cellular response to epinephrine stimulus);GO:0005546(phosphatidylinositol-4,5-bisphosphate binding);GO:0015386(potassium:proton antiporter activity);GO:0030346(protein phosphatase 2B binding);GO:0086040(sodium:proton antiporter activity involved in regulation of cardiac muscle cell membrane potential);GO:0002026(regulation of the force of heart contraction);GO:0010447(response to acidic pH);GO:0014070(response to organic cyclic compound);GO:0016049(cell growth);GO:0030011(maintenance of cell polarity);GO:0030154(cell differentiation);GO:0030307(positive regulation of cell growth);GO:0032869(cellular response to insulin stimulus);GO:0035794(positive regulation of mitochondrial membrane permeability);GO:0042493(response to drug);GO:0043065(positive regulation of apoptotic process);GO:0043066(negative regulation of apoptotic process);GO:0045760(positive regulation of action potential);GO:0051492(regulation of stress fiber assembly);GO:0051893(regulation of focal adhesion assembly);GO:0051930(regulation of sensory perception of pain);GO:0055007(cardiac muscle cell differentiation);GO:0070886(positive regulation of calcineurin-NFAT signaling cascade);GO:0070997(neuron death);GO:0071236(cellular response to antibiotic);GO:0071257(cellular response to electrical stimulus);GO:0071260(cellular response to mechanical stimulus);GO:0071407(cellular response to organic cyclic compound);GO:0071436(sodium ion export);GO:0071456(cellular response to hypoxia);GO:0071468(cellular response to acidic pH);GO:0071805(potassium ion transmembrane transport);GO:0086003(cardiac muscle cell contraction);GO:0086092(regulation of the force of heart contraction by cardiac conduction);GO:0098719(sodium ion import across plasma membrane);GO:0098735(positive regulation of the force of heart contraction);GO:1902533(positive regulation of intracellular signal transduction);GO:1902600(hydrogen ion transmembrane transport);GO:0005739(mitochondrion);GO:0009986(cell surface);GO:0014704(intercalated disc);GO:0016323(basolateral plasma membrane);GO:0016324(apical plasma membrane);GO:0030315(T-tubule);GO:0042383(sarcolemma);GO:0048471(perinuclear region of cytoplasm);GO:0090533(cation-transporting ATPase complex);GO:0035725(sodium ion transmembrane transport);GO:0035725(sodium ion transmembrane transport)","04371(Apelin signaling pathway);04024(cAMP signaling pathway);04810(Regulation of actin cytoskeleton);04919(Thyroid hormone signaling pathway);04260(Cardiac muscle contraction);04261(Adrenergic signaling in cardiomyocytes);04970(Salivary secretion);04971(Gastric acid secretion);04972(Pancreatic secretion);04976(Bile secretion);05205(Proteoglycans in cancer);05205(Proteoglycans in cancer)","K05742","NA","solute carrier family 9 member A1 [Source:HGNC Symbol;Acc:HGNC:11071]",{"v":2.27576930130566,"d":"2.28"},{"v":0.823857127720121,"d":"0.82"},{"v":2.76233490581486,"d":"2.76"},{"v":1.46588824271959,"d":"1.47"},{"v":0.0733889669963938,"d":"0.07"},{"v":0.582135795928719,"d":"0.58"},"up","no"]
["MSTRG.10510","PHF5A","ENST00000491254;ENST00000216252;ENST00000459687","GO:0003723(RNA binding);GO:0006397(mRNA processing);GO:0008380(RNA splicing);GO:0005634(nucleus);GO:0016607(nuclear speck);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0005681(spliceosomal complex);GO:0045893(positive regulation of transcription, DNA-templated);GO:0016363(nuclear matrix);GO:0005654(nucleoplasm);GO:0000398(mRNA splicing, via spliceosome);GO:0071011(precatalytic spliceosome);GO:0071013(catalytic step 2 spliceosome);GO:0005689(U12-type spliceosomal complex);GO:0005686(U2 snRNP);GO:0005686(U2 snRNP)","03040(Spliceosome);03040(Spliceosome)","K12834","NA","PHD finger protein 5A [Source:HGNC Symbol;Acc:HGNC:18000]",{"v":13.561463237247,"d":"13.56"},{"v":25.6858609230769,"d":"25.69"},{"v":0.527973863825721,"d":"0.53"},{"v":-0.921461580951918,"d":"-0.92"},{"v":0.073459640755641,"d":"0.07"},{"v":0.582135795928719,"d":"0.58"},"down","no"]
["MSTRG.7782","UBL5","ENST00000586895;ENST00000358666;ENST00000589372;ENST00000589960;ENST00000593087;ENST00000588141;ENST00000590068;ENST00000588595","GO:0005737(cytoplasm);GO:0005515(protein binding);GO:0005634(nucleus);GO:0003674(molecular_function);GO:0008150(biological_process);GO:0000398(mRNA splicing, via spliceosome);GO:1903955(positive regulation of protein targeting to mitochondrion);GO:0031386(protein tag);GO:0006464(cellular protein modification process);GO:0006464(cellular protein modification process)","NA","NA","NA","ubiquitin like 5 [Source:HGNC Symbol;Acc:HGNC:13736]",{"v":11.3078599782496,"d":"11.31"},{"v":21.4093032806836,"d":"21.41"},{"v":0.528175056889966,"d":"0.53"},{"v":-0.920911923164335,"d":"-0.92"},{"v":0.07347491221884,"d":"0.07"},{"v":0.582135795928719,"d":"0.58"},"down","no"]
["ENSG00000186017","ZNF566","ENST00000424129;ENST00000392170;ENST00000452939;ENST00000480361;ENST00000460937;ENST00000427002;ENST00000434377","GO:0003676(nucleic acid binding);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0005622(intracellular);GO:0005622(intracellular)","NA","NA","NA","zinc finger protein 566 [Source:HGNC Symbol;Acc:HGNC:25919]",{"v":0.122143337756519,"d":"0.12"},{"v":0.253974819935195,"d":"0.25"},{"v":0.480926958773651,"d":"0.48"},{"v":-1.05611029489762,"d":"-1.06"},{"v":0.0734875636641266,"d":"0.07"},{"v":0.582135795928719,"d":"0.58"},"down","no"]
["ENSG00000005889","ZFX","ENST00000304543;ENST00000379177;ENST00000480195;ENST00000428571;ENST00000379188;ENST00000497813;ENST00000474385;ENST00000419690","GO:0005634(nucleus);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0046872(metal ion binding);GO:0003676(nucleic acid binding);GO:0005730(nucleolus);GO:0005654(nucleoplasm);GO:0006351(transcription, DNA-templated);GO:0003713(transcription coactivator activity);GO:0007275(multicellular organism development);GO:0007275(multicellular organism development)","NA","NA","NA","zinc finger protein, X-linked [Source:HGNC Symbol;Acc:HGNC:12869]",{"v":3.29304120482461,"d":"3.29"},{"v":1.19418915436539,"d":"1.19"},{"v":2.75755410504844,"d":"2.76"},{"v":1.46338919273209,"d":"1.46"},{"v":0.0735677061414792,"d":"0.07"},{"v":0.582373395651669,"d":"0.58"},"up","no"]
["MSTRG.1946","ARL3","ENST00000260746","GO:0006810(transport);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0015031(protein transport);GO:0005525(GTP binding);GO:0007264(small GTPase mediated signal transduction);GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0005794(Golgi apparatus);GO:0005622(intracellular);GO:0051301(cell division);GO:0005813(centrosome);GO:0005856(cytoskeleton);GO:0042995(cell projection);GO:0005515(protein binding);GO:0007049(cell cycle);GO:0000139(Golgi membrane);GO:0008017(microtubule binding);GO:0005815(microtubule organizing center);GO:0005819(spindle);GO:0030496(midbody);GO:0060271(cilium assembly);GO:0005929(cilium);GO:0070062(extracellular exosome);GO:0005876(spindle microtubule);GO:0019003(GDP binding);GO:0000910(cytokinesis);GO:0032391(photoreceptor connecting cilium);GO:0005881(cytoplasmic microtubule);GO:0001822(kidney development);GO:0006892(post-Golgi vesicle-mediated transport);GO:0003924(GTPase activity);GO:0007224(smoothened signaling pathway);GO:0042073(intraciliary transport);GO:0042461(photoreceptor cell development)","NA","NA","NA","ADP ribosylation factor like GTPase 3 [Source:HGNC Symbol;Acc:HGNC:694]",{"v":1.257654,"d":"1.26"},{"v":2.39642,"d":"2.40"},{"v":0.524805334624148,"d":"0.52"},{"v":-0.930145709922435,"d":"-0.93"},{"v":0.0736418086266019,"d":"0.07"},{"v":0.582518418312992,"d":"0.58"},"down","no"]
["MSTRG.506","AL139220.2","MSTRG.506.1;ENST00000607988;ENST00000447959;ENST00000623351;ENST00000609027","NA","NA","NA","NA",null,{"v":0.314766766006843,"d":"0.31"},{"v":0.60841168230694,"d":"0.61"},{"v":0.517358188806186,"d":"0.52"},{"v":-0.95076463004014,"d":"-0.95"},{"v":0.0737554612200862,"d":"0.07"},{"v":0.582518418312992,"d":"0.58"},"down","no"]
["MSTRG.7947","AC024075.2","ENST00000598112","NA","NA","NA","NA",null,{"v":1.926349,"d":"1.93"},{"v":0.671776,"d":"0.67"},{"v":2.86754662268375,"d":"2.87"},{"v":1.51981694282971,"d":"1.52"},{"v":0.0737647665993262,"d":"0.07"},{"v":0.582518418312992,"d":"0.58"},"up","no"]
["ENSG00000166860","ZBTB39","ENST00000300101","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding)","NA","NA","NA","zinc finger and BTB domain containing 39 [Source:HGNC Symbol;Acc:HGNC:29014]",{"v":1.996514,"d":"2.00"},{"v":0.722679,"d":"0.72"},{"v":2.76265672587691,"d":"2.76"},{"v":1.46605631110379,"d":"1.47"},{"v":0.0737866695374504,"d":"0.07"},{"v":0.582518418312992,"d":"0.58"},"up","no"]
["MSTRG.8375","SIGLEC10","ENST00000353836;ENST00000442846;ENST00000441969;ENST00000339313;ENST00000525998;ENST00000439889;ENST00000529627;ENST00000524527;ENST00000357375;ENST00000436984","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0030246(carbohydrate binding);GO:0007155(cell adhesion);GO:0005886(plasma membrane);GO:0005576(extracellular region);GO:0005576(extracellular region)","NA","NA","NA","sialic acid binding Ig like lectin 10 [Source:HGNC Symbol;Acc:HGNC:15620]",{"v":13.7993521543496,"d":"13.80"},{"v":5.02439414507772,"d":"5.02"},{"v":2.74647086910339,"d":"2.75"},{"v":1.45757898975447,"d":"1.46"},{"v":0.0738789801274235,"d":"0.07"},{"v":0.582602134701826,"d":"0.58"},"up","no"]
["MSTRG.14038","CASP2","ENST00000310447;ENST00000472067;ENST00000350623;ENST00000619992;ENST00000392925;ENST00000493642","GO:0005634(nucleus);GO:0016787(hydrolase activity);GO:0042981(regulation of apoptotic process);GO:0005515(protein binding);GO:0008233(peptidase activity);GO:0008234(cysteine-type peptidase activity);GO:0006508(proteolysis);GO:0006915(apoptotic process);GO:0004197(cysteine-type endopeptidase activity);GO:0042802(identical protein binding);GO:0005737(cytoplasm);GO:0097153(cysteine-type endopeptidase activity involved in apoptotic process);GO:0001554(luteolysis);GO:0003407(neural retina development);GO:0007420(brain development);GO:0007568(aging);GO:0035234(ectopic germ cell programmed cell death);GO:0043525(positive regulation of neuron apoptotic process);GO:0097190(apoptotic signaling pathway);GO:0097192(extrinsic apoptotic signaling pathway in absence of ligand);GO:2001235(positive regulation of apoptotic signaling pathway);GO:0005739(mitochondrion);GO:0016020(membrane);GO:0005829(cytosol);GO:0019904(protein domain specific binding);GO:0043065(positive regulation of apoptotic process);GO:0043066(negative regulation of apoptotic process);GO:0019899(enzyme binding);GO:0071260(cellular response to mechanical stimulus);GO:0006919(activation of cysteine-type endopeptidase activity involved in apoptotic process);GO:0016485(protein processing);GO:0097200(cysteine-type endopeptidase activity involved in execution phase of apoptosis);GO:0097194(execution phase of apoptosis);GO:0008630(intrinsic apoptotic signaling pathway in response to DNA damage);GO:0006977(DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest);GO:0006977(DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest)","04210(Apoptosis);04210(Apoptosis)","K02186","EC:3.4.22.55","caspase 2 [Source:HGNC Symbol;Acc:HGNC:1503]",{"v":4.89062544513716,"d":"4.89"},{"v":1.78164994588529,"d":"1.78"},{"v":2.74499794779105,"d":"2.74"},{"v":1.45680507064658,"d":"1.46"},{"v":0.0738976099557212,"d":"0.07"},{"v":0.582602134701826,"d":"0.58"},"up","no"]
["MSTRG.1876","RPL13AP5","ENST00000439189","NA","NA","NA","NA","ribosomal protein L13a pseudogene 5 [Source:HGNC Symbol;Acc:HGNC:23736]",{"v":156.82402,"d":"156.82"},{"v":295.585022,"d":"295.59"},{"v":0.530554690961303,"d":"0.53"},{"v":-0.914426619314179,"d":"-0.91"},{"v":0.0739869741842547,"d":"0.07"},{"v":0.582858517045618,"d":"0.58"},"down","no"]
["MSTRG.1057","SSR2","ENST00000295702;ENST00000480567;ENST00000467041;ENST00000532074;ENST00000480176;ENST00000368311;ENST00000473699;ENST00000466905;ENST00000526212;ENST00000496742;ENST00000529008;ENST00000472898;ENST00000531917;ENST00000488179;ENST00000472467;ENST00000531790","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0006613(cotranslational protein targeting to membrane);GO:0006613(cotranslational protein targeting to membrane)","04141(Protein processing in endoplasmic reticulum);04141(Protein processing in endoplasmic reticulum)","K13250","NA","signal sequence receptor subunit 2 [Source:HGNC Symbol;Acc:HGNC:11324]",{"v":16.869963052774,"d":"16.87"},{"v":31.8080395178169,"d":"31.81"},{"v":0.530367897817924,"d":"0.53"},{"v":-0.91493464044081,"d":"-0.91"},{"v":0.0741151783678881,"d":"0.07"},{"v":0.582858517045618,"d":"0.58"},"down","no"]
["ENSG00000261609","GAN","ENST00000568107","GO:0005737(cytoplasm);GO:0016567(protein ubiquitination);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0007010(cytoskeleton organization);GO:0004842(ubiquitin-protein transferase activity);GO:0003674(molecular_function);GO:0005829(cytosol);GO:0043687(post-translational protein modification);GO:0031463(Cul3-RING ubiquitin ligase complex)","NA","NA","NA","gigaxonin [Source:HGNC Symbol;Acc:HGNC:4137]",{"v":0.472515515253797,"d":"0.47"},{"v":0.169505641178762,"d":"0.17"},{"v":2.78760937965173,"d":"2.79"},{"v":1.47902841431911,"d":"1.48"},{"v":0.0741652942489463,"d":"0.07"},{"v":0.582858517045618,"d":"0.58"},"up","no"]
["MSTRG.10475","RPL3","ENST00000465618;ENST00000216146;ENST00000401609;ENST00000467105;ENST00000473638;ENST00000484358;ENST00000481985;ENST00000471290;ENST00000461967;ENST00000484615;ENST00000427905;ENST00000460589;ENST00000420536;ENST00000498462;ENST00000464182;ENST00000402527;ENST00000453303","GO:0005730(nucleolus);GO:0005829(cytosol);GO:0030529(intracellular ribonucleoprotein complex);GO:0005622(intracellular);GO:0003735(structural constituent of ribosome);GO:0006412(translation);GO:0005840(ribosome);GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005925(focal adhesion);GO:0000027(ribosomal large subunit assembly);GO:0005515(protein binding);GO:0070062(extracellular exosome);GO:0043234(protein complex);GO:0006413(translational initiation);GO:0006364(rRNA processing);GO:0000184(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay);GO:0019083(viral transcription);GO:0006614(SRP-dependent cotranslational protein targeting to membrane);GO:0022625(cytosolic large ribosomal subunit);GO:0008097(5S rRNA binding);GO:0071353(cellular response to interleukin-4);GO:0071353(cellular response to interleukin-4)","03010(Ribosome);03010(Ribosome)","K02925","NA","ribosomal protein L3 [Source:HGNC Symbol;Acc:HGNC:10332]",{"v":196.534526353727,"d":"196.53"},{"v":370.089525301524,"d":"370.09"},{"v":0.53104590353808,"d":"0.53"},{"v":-0.913091522098172,"d":"-0.91"},{"v":0.0741746778439944,"d":"0.07"},{"v":0.582858517045618,"d":"0.58"},"down","no"]
["MSTRG.8316","RPL13A;ALDH16A1;FLT3LG;AC010619.2","ENST00000479992;ENST00000474171;ENST00000624069;ENST00000391857;ENST00000467825;ENST00000593417;ENST00000597551;ENST00000598555;ENST00000484279;ENST00000600429;ENST00000204637;ENST00000601800;ENST00000596435;ENST00000594009;ENST00000293350;ENST00000472481;ENST00000476268;ENST00000597914;ENST00000468655;ENST00000598472;ENST00000595815;ENST00000594549;ENST00000476300;ENST00000621674;ENST00000486930;ENST00000477613;ENST00000488946;ENST00000595510;ENST00000593422;ENST00000599652;ENST00000600084;ENST00000600265","GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0006412(translation);GO:0030529(intracellular ribonucleoprotein complex);GO:0003735(structural constituent of ribosome);GO:0005840(ribosome);GO:0015934(large ribosomal subunit);GO:0005730(nucleolus);GO:0005925(focal adhesion);GO:0005829(cytosol);GO:0006417(regulation of translation);GO:0003729(mRNA binding);GO:0071346(cellular response to interferon-gamma);GO:0017148(negative regulation of translation);GO:0006413(translational initiation);GO:0006364(rRNA processing);GO:0000184(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay);GO:0019083(viral transcription);GO:0097452(GAIT complex);GO:0006614(SRP-dependent cotranslational protein targeting to membrane);GO:0022625(cytosolic large ribosomal subunit);GO:1901194(negative regulation of formation of translation preinitiation complex);GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0008152(metabolic process);GO:0070062(extracellular exosome);GO:0004029(aldehyde dehydrogenase (NAD) activity);GO:0005125(cytokine activity);GO:0016021(integral component of membrane);GO:0005886(plasma membrane);GO:0005576(extracellular region);GO:0005615(extracellular space);GO:0008284(positive regulation of cell proliferation);GO:0007165(signal transduction);GO:0005102(receptor binding);GO:0035162(embryonic hemopoiesis);GO:0030971(receptor tyrosine kinase binding);GO:0042803(protein homodimerization activity);GO:0001934(positive regulation of protein phosphorylation);GO:0030098(lymphocyte differentiation);GO:0030885(regulation of myeloid dendritic cell activation);GO:0032825(positive regulation of natural killer cell differentiation);GO:0045663(positive regulation of myoblast differentiation);GO:0045787(positive regulation of cell cycle);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0048873(homeostasis of number of cells within a tissue);GO:0071864(positive regulation of cell proliferation in bone marrow);GO:0071866(negative regulation of apoptotic process in bone marrow);GO:0090290(positive regulation of osteoclast proliferation);GO:1901741(positive regulation of myoblast fusion);GO:0009986(cell surface);GO:0031233(intrinsic component of external side of plasma membrane);GO:0004029(aldehyde dehydrogenase (NAD) activity)","03010(Ribosome);04014(Ras signaling pathway);04010(MAPK signaling pathway);04151(PI3K-Akt signaling pathway);04060(Cytokine-cytokine receptor interaction);04640(Hematopoietic cell lineage);05200(Pathways in cancer);05200(Pathways in cancer)","K02872;K05454","NA","ribosomal protein L13a [Source:HGNC Symbol;Acc:HGNC:10304];aldehyde dehydrogenase 16 family member A1 [Source:HGNC Symbol;Acc:HGNC:28114];fms related tyrosine kinase 3 ligand [Source:HGNC Symbol;Acc:HGNC:3766]",{"v":105.440401085329,"d":"105.44"},{"v":198.544101902453,"d":"198.54"},{"v":0.531067909220154,"d":"0.53"},{"v":-0.913031740391121,"d":"-0.91"},{"v":0.0741810805298737,"d":"0.07"},{"v":0.582858517045618,"d":"0.58"},"down","no"]
["MSTRG.6796","RARA","ENST00000394089;ENST00000394081;ENST00000254066;ENST00000420042;ENST00000425707;ENST00000577646;ENST00000579727;ENST00000582914","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0005829(cytosol);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0031490(chromatin DNA binding);GO:0043565(sequence-specific DNA binding);GO:0015629(actin cytoskeleton);GO:0005515(protein binding);GO:0003707(steroid hormone receptor activity);GO:0043401(steroid hormone mediated signaling pathway);GO:0003713(transcription coactivator activity);GO:0045893(positive regulation of transcription, DNA-templated);GO:0003714(transcription corepressor activity);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0005654(nucleoplasm);GO:0003708(retinoic acid receptor activity);GO:0048384(retinoic acid receptor signaling pathway);GO:0005102(receptor binding);GO:0008284(positive regulation of cell proliferation);GO:0009986(cell surface);GO:0019899(enzyme binding);GO:0019904(protein domain specific binding);GO:0032689(negative regulation of interferon-gamma production);GO:0032720(negative regulation of tumor necrosis factor production);GO:0008134(transcription factor binding);GO:0045892(negative regulation of transcription, DNA-templated);GO:0000790(nuclear chromatin);GO:0046982(protein heterodimerization activity);GO:0006367(transcription initiation from RNA polymerase II promoter);GO:0006468(protein phosphorylation);GO:0071300(cellular response to retinoic acid);GO:0043277(apoptotic cell clearance);GO:0032526(response to retinoic acid);GO:0045787(positive regulation of cell cycle);GO:0071391(cellular response to estrogen stimulus);GO:0001972(retinoic acid binding);GO:0051018(protein kinase A binding);GO:0007165(signal transduction);GO:0043422(protein kinase B binding);GO:0000900(translation repressor activity, nucleic acid binding);GO:0000975(regulatory region DNA binding);GO:0000977(RNA polymerase II regulatory region sequence-specific DNA binding);GO:0001012(RNA polymerase II regulatory region DNA binding);GO:0004879(RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding);GO:0008144(drug binding);GO:0042826(histone deacetylase binding);GO:0044212(transcription regulatory region DNA binding);GO:0044323(retinoic acid-responsive element binding);GO:0048027(mRNA 5'-UTR binding);GO:0051393(alpha-actinin binding);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0001657(ureteric bud development);GO:0001843(neural tube closure);GO:0001889(liver development);GO:0002068(glandular epithelial cell development);GO:0003148(outflow tract septum morphogenesis);GO:0003417(growth plate cartilage development);GO:0007281(germ cell development);GO:0007283(spermatogenesis);GO:0007565(female pregnancy);GO:0008285(negative regulation of cell proliferation);GO:0008584(male gonad development);GO:0010628(positive regulation of gene expression);GO:0010629(negative regulation of gene expression);GO:0017148(negative regulation of translation);GO:0021766(hippocampus development);GO:0030850(prostate gland development);GO:0030852(regulation of granulocyte differentiation);GO:0030853(negative regulation of granulocyte differentiation);GO:0031076(embryonic camera-type eye development);GO:0031641(regulation of myelination);GO:0032355(response to estradiol);GO:0032736(positive regulation of interleukin-13 production);GO:0032753(positive regulation of interleukin-4 production);GO:0032754(positive regulation of interleukin-5 production);GO:0033189(response to vitamin A);GO:0034097(response to cytokine);GO:0035264(multicellular organism growth);GO:0042981(regulation of apoptotic process);GO:0043066(negative regulation of apoptotic process);GO:0045471(response to ethanol);GO:0045596(negative regulation of cell differentiation);GO:0045630(positive regulation of T-helper 2 cell differentiation);GO:0045666(positive regulation of neuron differentiation);GO:0045947(negative regulation of translational initiation);GO:0048167(regulation of synaptic plasticity);GO:0051099(positive regulation of binding);GO:0055012(ventricular cardiac muscle cell differentiation);GO:0060010(Sertoli cell fate commitment);GO:0060173(limb development);GO:0060324(face development);GO:0060348(bone development);GO:0060534(trachea cartilage development);GO:0060591(chondroblast differentiation);GO:0061037(negative regulation of cartilage development);GO:0071222(cellular response to lipopolysaccharide);GO:0030425(dendrite);GO:0043005(neuron projection);GO:0043025(neuronal cell body);GO:0048471(perinuclear region of cytoplasm);GO:0048471(perinuclear region of cytoplasm)","04659(Th17 cell differentiation);05200(Pathways in cancer);05202(Transcriptional misregulation in cancers);05221(Acute myeloid leukemia);05221(Acute myeloid leukemia)","K08527","NA","retinoic acid receptor alpha [Source:HGNC Symbol;Acc:HGNC:9864]",{"v":21.1168788583809,"d":"21.12"},{"v":7.71699839230607,"d":"7.72"},{"v":2.73641094436856,"d":"2.74"},{"v":1.45228490525416,"d":"1.45"},{"v":0.0744374164766509,"d":"0.07"},{"v":0.584061807862528,"d":"0.58"},"up","no"]
["MSTRG.13045","CNPY3;AL035587.1","MSTRG.13045.1;ENST00000372836;ENST00000450671;MSTRG.13045.3;ENST00000607218;ENST00000394142","GO:0005783(endoplasmic reticulum);GO:0002376(immune system process);GO:0045087(innate immune response);GO:0002224(toll-like receptor signaling pathway);GO:0005788(endoplasmic reticulum lumen);GO:0005102(receptor binding);GO:0005102(receptor binding)","NA","NA","NA","canopy FGF signaling regulator 3 [Source:HGNC Symbol;Acc:HGNC:11968]",{"v":15.5288535220799,"d":"15.53"},{"v":29.2282631284649,"d":"29.23"},{"v":0.531295802758687,"d":"0.53"},{"v":-0.912412779334323,"d":"-0.91"},{"v":0.0744587150047318,"d":"0.07"},{"v":0.584061807862528,"d":"0.58"},"down","no"]
["MSTRG.5663","NPIPB2","ENST00000399147;ENST00000538896;ENST00000547494;ENST00000356023;ENST00000532936;ENST00000540412;ENST00000620285","GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005654(nucleoplasm)","NA","NA","NA","nuclear pore complex interacting protein family, member B2 [Source:HGNC Symbol;Acc:HGNC:37451]",{"v":0.827451073924237,"d":"0.83"},{"v":0.280955826406767,"d":"0.28"},{"v":2.94512872185913,"d":"2.95"},{"v":1.55833069087389,"d":"1.56"},{"v":0.0744851061262726,"d":"0.07"},{"v":0.584061807862528,"d":"0.58"},"up","no"]
["MSTRG.13242","AL450405.1","ENST00000443998","NA","NA","NA","NA",null,{"v":53.997166,"d":"54.00"},{"v":101.768501,"d":"101.77"},{"v":0.530588202335809,"d":"0.53"},{"v":-0.914335497384919,"d":"-0.91"},{"v":0.07458208733044,"d":"0.07"},{"v":0.584243072803894,"d":"0.58"},"down","no"]
["ENSG00000189079","ARID2","ENST00000334344;ENST00000479608;ENST00000457135;ENST00000422737;ENST00000477947;ENST00000480128;ENST00000426776","GO:0008285(negative regulation of cell proliferation);GO:0030336(negative regulation of cell migration);GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0005654(nucleoplasm);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0016569(covalent chromatin modification);GO:0003677(DNA binding);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0006337(nucleosome disassembly);GO:0003007(heart morphogenesis);GO:0042592(homeostatic process);GO:0048568(embryonic organ development);GO:0060038(cardiac muscle cell proliferation);GO:0060982(coronary artery morphogenesis);GO:0072358(cardiovascular system development);GO:0090544(BAF-type complex);GO:0090544(BAF-type complex)","05225(Hepatocellular carcinoma);05225(Hepatocellular carcinoma)","K11765","NA","AT-rich interaction domain 2 [Source:HGNC Symbol;Acc:HGNC:18037]",{"v":3.45632241824029,"d":"3.46"},{"v":1.26108792364146,"d":"1.26"},{"v":2.74074658352129,"d":"2.74"},{"v":1.45456893903604,"d":"1.45"},{"v":0.0746318548911264,"d":"0.07"},{"v":0.584243072803894,"d":"0.58"},"up","no"]
["ENSG00000158006","PAFAH2","ENST00000374282;ENST00000374284;ENST00000441420;ENST00000493892;ENST00000439092;ENST00000464540;ENST00000476611","GO:0005737(cytoplasm);GO:0016787(hydrolase activity);GO:0006629(lipid metabolic process);GO:0016042(lipid catabolic process);GO:0005789(endoplasmic reticulum membrane);GO:0007596(blood coagulation);GO:0005543(phospholipid binding);GO:0003847(1-alkyl-2-acetylglycerophosphocholine esterase activity);GO:0043066(negative regulation of apoptotic process);GO:0043066(negative regulation of apoptotic process)","00565(Ether lipid metabolism);00565(Ether lipid metabolism)","K01062","EC:3.1.1.47","platelet activating factor acetylhydrolase 2 [Source:HGNC Symbol;Acc:HGNC:8579]",{"v":2.69980098018253,"d":"2.70"},{"v":5.11290544119948,"d":"5.11"},{"v":0.528036555972207,"d":"0.53"},{"v":-0.921290284064598,"d":"-0.92"},{"v":0.0746591509550485,"d":"0.07"},{"v":0.584243072803894,"d":"0.58"},"down","no"]
["MSTRG.7005","PPP1R9B","ENST00000612501;ENST00000513579","GO:0003779(actin binding);GO:0006468(protein phosphorylation);GO:0050804(modulation of synaptic transmission);GO:0008157(protein phosphatase 1 binding);GO:0042127(regulation of cell proliferation);GO:0004672(protein kinase activity);GO:0004864(protein phosphatase inhibitor activity);GO:0008022(protein C-terminus binding);GO:0019900(kinase binding);GO:0031749(D2 dopamine receptor binding);GO:0032403(protein complex binding);GO:0044325(ion channel binding);GO:0051015(actin filament binding);GO:0001932(regulation of protein phosphorylation);GO:0001975(response to amphetamine);GO:0003006(developmental process involved in reproduction);GO:0007015(actin filament organization);GO:0007568(aging);GO:0007612(learning);GO:0010243(response to organonitrogen compound);GO:0014070(response to organic cyclic compound);GO:0016358(dendrite development);GO:0019722(calcium-mediated signaling);GO:0021766(hippocampus development);GO:0021987(cerebral cortex development);GO:0030042(actin filament depolymerization);GO:0032355(response to estradiol);GO:0032515(negative regulation of phosphoprotein phosphatase activity);GO:0034695(response to prostaglandin E);GO:0035094(response to nicotine);GO:0035690(cellular response to drug);GO:0035902(response to immobilization stress);GO:0042493(response to drug);GO:0043200(response to amino acid);GO:0048545(response to steroid hormone);GO:0060179(male mating behavior);GO:0061458(reproductive system development);GO:0071315(cellular response to morphine);GO:0071364(cellular response to epidermal growth factor stimulus);GO:0071392(cellular response to estradiol stimulus);GO:0071407(cellular response to organic cyclic compound);GO:0071482(cellular response to light stimulus);GO:0090004(positive regulation of establishment of protein localization to plasma membrane);GO:0097338(response to clozapine);GO:1901653(cellular response to peptide);GO:1903119(protein localization to actin cytoskeleton);GO:1903829(positive regulation of cellular protein localization);GO:1904372(positive regulation of protein localization to actin cortical patch);GO:1904373(response to kainic acid);GO:1904386(response to L-phenylalanine derivative);GO:1990778(protein localization to cell periphery);GO:2000474(regulation of opioid receptor signaling pathway);GO:0005737(cytoplasm);GO:0005886(plasma membrane);GO:0014069(postsynaptic density);GO:0015629(actin cytoskeleton);GO:0030175(filopodium);GO:0030426(growth cone);GO:0030864(cortical actin cytoskeleton);GO:0032591(dendritic spine membrane);GO:0043005(neuron projection);GO:0043025(neuronal cell body);GO:0043197(dendritic spine);GO:0044326(dendritic spine neck);GO:0044327(dendritic spine head);GO:1990780(cytoplasmic side of dendritic spine plasma membrane);GO:1990780(cytoplasmic side of dendritic spine plasma membrane)","NA","NA","NA","protein phosphatase 1 regulatory subunit 9B [Source:HGNC Symbol;Acc:HGNC:9298]",{"v":40.7827002180084,"d":"40.78"},{"v":14.928002724523,"d":"14.93"},{"v":2.73195959101833,"d":"2.73"},{"v":1.44993614458386,"d":"1.45"},{"v":0.0748617396909461,"d":"0.07"},{"v":0.585228964752438,"d":"0.59"},"up","no"]
["ENSG00000148468","FAM171A1","ENST00000378116;ENST00000477161","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0070062(extracellular exosome);GO:0070062(extracellular exosome)","NA","NA","NA","family with sequence similarity 171 member A1 [Source:HGNC Symbol;Acc:HGNC:23522]",{"v":0.950758270543616,"d":"0.95"},{"v":0.334387809608091,"d":"0.33"},{"v":2.84328029678451,"d":"2.84"},{"v":1.50755633005584,"d":"1.51"},{"v":0.0749298216674238,"d":"0.07"},{"v":0.585228964752438,"d":"0.59"},"up","no"]
["ENSG00000112796","ENPP5","ENST00000492313;ENST00000371383;ENST00000230565","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0046872(metal ion binding);GO:0016787(hydrolase activity);GO:0003824(catalytic activity);GO:0005886(plasma membrane);GO:0008152(metabolic process);GO:0005576(extracellular region);GO:0007154(cell communication);GO:0007154(cell communication)","NA","NA","NA","ectonucleotide pyrophosphatase/phosphodiesterase 5 (putative) [Source:HGNC Symbol;Acc:HGNC:13717]",{"v":0.48649039141651,"d":"0.49"},{"v":0.944149326923077,"d":"0.94"},{"v":0.515268483007822,"d":"0.52"},{"v":-0.956603743807026,"d":"-0.96"},{"v":0.0749363188312129,"d":"0.07"},{"v":0.585228964752438,"d":"0.59"},"down","no"]
["MSTRG.12864","LST1","ENST00000376099;MSTRG.12864.4;ENST00000376096;ENST00000418507;ENST00000303757;MSTRG.12864.8;ENST00000438075;ENST00000376090;ENST00000396101;ENST00000376089;ENST00000376093;ENST00000464526;ENST00000396112;MSTRG.12864.3;ENST00000376092;ENST00000490742;ENST00000464044;MSTRG.12864.2;ENST00000376110;ENST00000433492;MSTRG.12864.1;ENST00000339530;ENST00000460834;ENST00000419073;ENST00000376086;ENST00000211921;MSTRG.12864.9","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005794(Golgi apparatus);GO:0006955(immune response);GO:0000139(Golgi membrane);GO:0002376(immune system process);GO:0000902(cell morphogenesis);GO:0012505(endomembrane system);GO:0008360(regulation of cell shape);GO:0016358(dendrite development);GO:0009653(anatomical structure morphogenesis);GO:0050672(negative regulation of lymphocyte proliferation);GO:0050672(negative regulation of lymphocyte proliferation)","NA","NA","NA","leukocyte specific transcript 1 [Source:HGNC Symbol;Acc:HGNC:14189]",{"v":31.3036887830157,"d":"31.30"},{"v":58.8303045750585,"d":"58.83"},{"v":0.532101423052756,"d":"0.53"},{"v":-0.910226833015789,"d":"-0.91"},{"v":0.0751900083085495,"d":"0.08"},{"v":0.586441609716554,"d":"0.59"},"down","no"]
["MSTRG.11973","EEF1A1P13","ENST00000503537","NA","NA","NA","NA","eukaryotic translation elongation factor 1 alpha 1 pseudogene 13 [Source:HGNC Symbol;Acc:HGNC:3196]",{"v":1.51886,"d":"1.52"},{"v":2.913231,"d":"2.91"},{"v":0.521366139520004,"d":"0.52"},{"v":-0.939631205786137,"d":"-0.94"},{"v":0.075199345958982,"d":"0.08"},{"v":0.586441609716554,"d":"0.59"},"down","no"]
["MSTRG.12950","RGL2;TAPBP","MSTRG.12950.1;ENST00000480730;ENST00000426633;ENST00000483151;ENST00000478610;ENST00000434618;ENST00000476333;ENST00000437840;ENST00000476616;ENST00000471319;ENST00000494550;ENST00000437116;ENST00000497454;ENST00000467025;ENST00000485077;ENST00000425946;MSTRG.12950.2;ENST00000456592;ENST00000460988;ENST00000489157;ENST00000475304","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005515(protein binding);GO:0000139(Golgi membrane);GO:0019885(antigen processing and presentation of endogenous peptide antigen via MHC class I);GO:0006890(retrograde vesicle-mediated transport, Golgi to ER);GO:0002479(antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent);GO:0010468(regulation of gene expression);GO:0030670(phagocytic vesicle membrane);GO:0006955(immune response);GO:0006461(protein complex assembly);GO:0051082(unfolded protein binding);GO:0033116(endoplasmic reticulum-Golgi intermediate compartment membrane);GO:0042825(TAP complex);GO:0015433(peptide antigen-transporting ATPase activity);GO:0042288(MHC class I protein binding);GO:0042605(peptide antigen binding);GO:0046978(TAP1 binding);GO:0046979(TAP2 binding);GO:0002474(antigen processing and presentation of peptide antigen via MHC class I);GO:0015833(peptide transport);GO:0042886(amide transport);GO:0050823(peptide antigen stabilization);GO:0061635(regulation of protein complex stability);GO:1990668(vesicle fusion with endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membrane);GO:0042824(MHC class I peptide loading complex);GO:0071556(integral component of lumenal side of endoplasmic reticulum membrane);GO:0002397(MHC class I protein complex assembly);GO:0005622(intracellular);GO:0007264(small GTPase mediated signal transduction);GO:0007165(signal transduction);GO:0043547(positive regulation of GTPase activity);GO:0005085(guanyl-nucleotide exchange factor activity);GO:0005089(Rho guanyl-nucleotide exchange factor activity);GO:0010667(negative regulation of cardiac muscle cell apoptotic process);GO:0014068(positive regulation of phosphatidylinositol 3-kinase signaling);GO:0032485(regulation of Ral protein signal transduction);GO:0005575(cellular_component);GO:0007265(Ras protein signal transduction);GO:0005088(Ras guanyl-nucleotide exchange factor activity);GO:0002397(MHC class I protein complex assembly)","04612(Antigen processing and presentation);04014(Ras signaling pathway);04612(Antigen processing and presentation)","K08058;K17636","NA","TAP binding protein [Source:HGNC Symbol;Acc:HGNC:11566];ral guanine nucleotide dissociation stimulator like 2 [Source:HGNC Symbol;Acc:HGNC:9769]",{"v":33.2204709120008,"d":"33.22"},{"v":12.1734743491872,"d":"12.17"},{"v":2.72892273471779,"d":"2.73"},{"v":1.44833154748215,"d":"1.45"},{"v":0.0752927419905414,"d":"0.08"},{"v":0.586441609716554,"d":"0.59"},"up","no"]
["ENSG00000166398","KIAA0355","ENST00000299505;ENST00000585833;ENST00000588974","NA","NA","NA","NA","KIAA0355 [Source:HGNC Symbol;Acc:HGNC:29016]",{"v":3.72159910886178,"d":"3.72"},{"v":1.35994155329133,"d":"1.36"},{"v":2.73658753926209,"d":"2.74"},{"v":1.45237800689779,"d":"1.45"},{"v":0.0752935882276227,"d":"0.08"},{"v":0.586441609716554,"d":"0.59"},"up","no"]
["MSTRG.1556","CAMK1D","ENST00000619168;ENST00000378845;ENST00000615792","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0003824(catalytic activity);GO:0008152(metabolic process);GO:0007399(nervous system development);GO:0006954(inflammatory response);GO:0005516(calmodulin binding);GO:0035556(intracellular signal transduction);GO:0018105(peptidyl-serine phosphorylation);GO:0050766(positive regulation of phagocytosis);GO:0018107(peptidyl-threonine phosphorylation);GO:0010976(positive regulation of neuron projection development);GO:0032793(positive regulation of CREB transcription factor activity);GO:0060267(positive regulation of respiratory burst);GO:0090023(positive regulation of neutrophil chemotaxis);GO:0004683(calmodulin-dependent protein kinase activity);GO:0050773(regulation of dendrite development);GO:0043065(positive regulation of apoptotic process);GO:0043066(negative regulation of apoptotic process);GO:0071622(regulation of granulocyte chemotaxis);GO:0071622(regulation of granulocyte chemotaxis)","04921(Oxytocin signaling pathway);04925(Aldosterone synthesis and secretion);04925(Aldosterone synthesis and secretion)","K08794","EC:2.7.11.17","calcium/calmodulin dependent protein kinase ID [Source:HGNC Symbol;Acc:HGNC:19341]",{"v":12.442182598037,"d":"12.44"},{"v":4.56104997534809,"d":"4.56"},{"v":2.72792069047378,"d":"2.73"},{"v":1.44780170113502,"d":"1.45"},{"v":0.0754928334689218,"d":"0.08"},{"v":0.587599380076802,"d":"0.59"},"up","no"]
["MSTRG.1369","TRAF5","ENST00000473385;ENST00000261464;ENST00000494355;ENST00000488428;ENST00000462410","GO:0051091(positive regulation of sequence-specific DNA binding transcription factor activity);GO:0005737(cytoplasm);GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0005829(cytosol);GO:0007165(signal transduction);GO:0042981(regulation of apoptotic process);GO:0005515(protein binding);GO:0006915(apoptotic process);GO:0043123(positive regulation of I-kappaB kinase/NF-kappaB signaling);GO:0005813(centrosome);GO:0042802(identical protein binding);GO:0031625(ubiquitin protein ligase binding);GO:0051092(positive regulation of NF-kappaB transcription factor activity);GO:0031996(thioesterase binding);GO:0009898(cytoplasmic side of plasma membrane);GO:0035631(CD40 receptor complex);GO:0035631(CD40 receptor complex)","04064(NF-kappa B signaling pathway);04668(TNF signaling pathway);04217(Necroptosis);04621(NOD-like receptor signaling pathway);04657(IL-17 signaling pathway);05200(Pathways in cancer);05203(Viral carcinogenesis);05222(Small cell lung cancer);05168(Herpes simplex infection);05169(Epstein-Barr virus infection);05169(Epstein-Barr virus infection)","K09849","NA","TNF receptor associated factor 5 [Source:HGNC Symbol;Acc:HGNC:12035]",{"v":1.26058083651075,"d":"1.26"},{"v":2.3735709058967,"d":"2.37"},{"v":0.531090448311053,"d":"0.53"},{"v":-0.91297051216759,"d":"-0.91"},{"v":0.0757293614281744,"d":"0.08"},{"v":0.588767366910914,"d":"0.59"},"down","no"]
["ENSG00000134548","SPX","ENST00000535033;ENST00000535139;ENST00000537527;ENST00000543800","GO:0005576(extracellular region);GO:0005615(extracellular space);GO:0031410(cytoplasmic vesicle);GO:0005179(hormone activity);GO:0005184(neuropeptide hormone activity);GO:0030133(transport vesicle);GO:0044539(long-chain fatty acid import);GO:0051930(regulation of sensory perception of pain);GO:0031045(dense core granule);GO:0032099(negative regulation of appetite);GO:0010459(negative regulation of heart rate);GO:0003084(positive regulation of systemic arterial blood pressure);GO:0035814(negative regulation of renal sodium excretion);GO:1904306(positive regulation of gastro-intestinal system smooth muscle contraction);GO:1904306(positive regulation of gastro-intestinal system smooth muscle contraction)","NA","NA","NA","spexin hormone [Source:HGNC Symbol;Acc:HGNC:28139]",{"v":0.226586586484073,"d":"0.23"},{"v":0.460833741887467,"d":"0.46"},{"v":0.491688359354997,"d":"0.49"},{"v":-1.02418389490397,"d":"-1.02"},{"v":0.0757442905506678,"d":"0.08"},{"v":0.588767366910914,"d":"0.59"},"down","no"]
["MSTRG.5452","CHD2;LINC01578;AC013394.1","ENST00000626874;ENST00000394196;ENST00000556895;ENST00000627622;MSTRG.5452.2;ENST00000420239;ENST00000557682;ENST00000625662;ENST00000555520;ENST00000628118;ENST00000635856;ENST00000626782;ENST00000628375;ENST00000554133;ENST00000629685;ENST00000629136;ENST00000557147;ENST00000625990;ENST00000630813;ENST00000554894;ENST00000555227;ENST00000628181;ENST00000636861;ENST00000629346;ENST00000630790;ENST00000627200;ENST00000554669;ENST00000630016;ENST00000635922;ENST00000553829;ENST00000629104;ENST00000627185;ENST00000637572","GO:0005634(nucleus);GO:0003723(RNA binding);GO:0043231(intracellular membrane-bounded organelle);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0005730(nucleolus);GO:0005654(nucleoplasm);GO:0006355(regulation of transcription, DNA-templated);GO:0016787(hydrolase activity);GO:0006351(transcription, DNA-templated);GO:0016569(covalent chromatin modification);GO:0004386(helicase activity);GO:0032508(DNA duplex unwinding);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0001046(core promoter sequence-specific DNA binding);GO:0070062(extracellular exosome);GO:0007517(muscle organ development);GO:0042393(histone binding);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0004003(ATP-dependent DNA helicase activity);GO:0006974(cellular response to DNA damage stimulus);GO:0060218(hematopoietic stem cell differentiation);GO:0060218(hematopoietic stem cell differentiation)","NA","NA","NA","chromodomain helicase DNA binding protein 2 [Source:HGNC Symbol;Acc:HGNC:1917];long intergenic non-protein coding RNA 1578 [Source:HGNC Symbol;Acc:HGNC:48626]",{"v":7.06424567425528,"d":"7.06"},{"v":2.58879410850266,"d":"2.59"},{"v":2.72877848842958,"d":"2.73"},{"v":1.44825528702148,"d":"1.45"},{"v":0.0758022658962766,"d":"0.08"},{"v":0.588823888865191,"d":"0.59"},"up","no"]
["MSTRG.15069","SURF2","ENST00000371964;ENST00000495524;ENST00000486887","GO:0016607(nuclear speck);GO:0005634(nucleus);GO:0005730(nucleolus);GO:0005886(plasma membrane);GO:0003674(molecular_function);GO:0008150(biological_process);GO:0005575(cellular_component);GO:0005575(cellular_component)","NA","NA","NA","surfeit 2 [Source:HGNC Symbol;Acc:HGNC:11475]",{"v":4.63064507936508,"d":"4.63"},{"v":8.76485691666667,"d":"8.76"},{"v":0.528319529159655,"d":"0.53"},{"v":-0.92051735525821,"d":"-0.92"},{"v":0.0759187854172329,"d":"0.08"},{"v":0.589221778296549,"d":"0.59"},"down","no"]
["ENSG00000163082","SGPP2","ENST00000321276","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016787(hydrolase activity);GO:0016311(dephosphorylation);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0042392(sphingosine-1-phosphate phosphatase activity);GO:0030148(sphingolipid biosynthetic process);GO:0070780(dihydrosphingosine-1-phosphate phosphatase activity);GO:0006670(sphingosine metabolic process)","00600(Sphingolipid metabolism);04071(Sphingolipid signaling pathway)","K04717","EC:3.1.3.-","sphingosine-1-phosphate phosphatase 2 [Source:HGNC Symbol;Acc:HGNC:19953]",{"v":0.897235,"d":"0.90"},{"v":0.314736,"d":"0.31"},{"v":2.8507542829546,"d":"2.85"},{"v":1.51134369341826,"d":"1.51"},{"v":0.0759549644458739,"d":"0.08"},{"v":0.589221778296549,"d":"0.59"},"up","no"]
["ENSG00000177455","CD19","ENST00000538922;ENST00000324662;ENST00000565089;ENST00000567541;ENST00000567368;ENST00000566890","GO:0005622(intracellular);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005515(protein binding);GO:0030449(regulation of complement activation);GO:0050776(regulation of immune response);GO:0005886(plasma membrane);GO:0050853(B cell receptor signaling pathway);GO:0046854(phosphatidylinositol phosphorylation);GO:0070062(extracellular exosome);GO:0005887(integral component of plasma membrane);GO:0043234(protein complex);GO:0007166(cell surface receptor signaling pathway);GO:0046934(phosphatidylinositol-4,5-bisphosphate 3-kinase activity);GO:0014066(regulation of phosphatidylinositol 3-kinase signaling);GO:0038111(interleukin-7-mediated signaling pathway);GO:0048015(phosphatidylinositol-mediated signaling);GO:0005057(signal transducer activity, downstream of receptor);GO:0006968(cellular defense response);GO:0009897(external side of plasma membrane);GO:0051281(positive regulation of release of sequestered calcium ion into cytosol);GO:0051281(positive regulation of release of sequestered calcium ion into cytosol)","04151(PI3K-Akt signaling pathway);04640(Hematopoietic cell lineage);04662(B cell receptor signaling pathway);05340(Primary immunodeficiency);05169(Epstein-Barr virus infection);05169(Epstein-Barr virus infection)","K06465","NA","CD19 molecule [Source:HGNC Symbol;Acc:HGNC:1633]",{"v":2.88380701733678,"d":"2.88"},{"v":5.4455766097381,"d":"5.45"},{"v":0.529568716778272,"d":"0.53"},{"v":-0.917110194573556,"d":"-0.92"},{"v":0.0761371951744823,"d":"0.08"},{"v":0.589733081928536,"d":"0.59"},"down","no"]
["MSTRG.9516","RNPEPL1","ENST00000270357;ENST00000481757;ENST00000486058;ENST00000471657;ENST00000451363;ENST00000498042;ENST00000464550;ENST00000437406;ENST00000460884;ENST00000493398","GO:0006508(proteolysis);GO:0070006(metalloaminopeptidase activity);GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0016787(hydrolase activity);GO:0008233(peptidase activity);GO:0008237(metallopeptidase activity);GO:0004177(aminopeptidase activity);GO:0005737(cytoplasm);GO:0042277(peptide binding);GO:0043171(peptide catabolic process);GO:0043171(peptide catabolic process)","NA","NA","NA","arginyl aminopeptidase like 1 [Source:HGNC Symbol;Acc:HGNC:10079]",{"v":15.5691013912546,"d":"15.57"},{"v":5.71581622842252,"d":"5.72"},{"v":2.72386318402533,"d":"2.72"},{"v":1.44565424054336,"d":"1.45"},{"v":0.076191488141131,"d":"0.08"},{"v":0.589733081928536,"d":"0.59"},"up","no"]
["MSTRG.13775","STEAP4","MSTRG.13775.2;ENST00000380079;ENST00000414498;ENST00000301959","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005794(Golgi apparatus);GO:0046872(metal ion binding);GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0006811(ion transport);GO:0005886(plasma membrane);GO:0000139(Golgi membrane);GO:0005887(integral component of plasma membrane);GO:0070062(extracellular exosome);GO:0045444(fat cell differentiation);GO:0005768(endosome);GO:0055072(iron ion homeostasis);GO:0008823(cupric reductase activity);GO:0052851(ferric-chelate reductase (NADPH) activity);GO:0015677(copper ion import);GO:0098706(ferric iron import across plasma membrane);GO:0098706(ferric iron import across plasma membrane)","NA","NA","NA","STEAP4 metalloreductase [Source:HGNC Symbol;Acc:HGNC:21923]",{"v":24.4203698906569,"d":"24.42"},{"v":8.9767152409992,"d":"8.98"},{"v":2.72041267156634,"d":"2.72"},{"v":1.44382551694019,"d":"1.44"},{"v":0.0762150992669564,"d":"0.08"},{"v":0.589733081928536,"d":"0.59"},"up","no"]
["ENSG00000119953","SMNDC1","ENST00000369603;ENST00000477763;ENST00000460483;ENST00000471297;ENST00000369592","GO:0005634(nucleus);GO:0003723(RNA binding);GO:0006397(mRNA processing);GO:0008380(RNA splicing);GO:0005737(cytoplasm);GO:0016607(nuclear speck);GO:0005515(protein binding);GO:0005681(spliceosomal complex);GO:0006915(apoptotic process);GO:0005654(nucleoplasm);GO:0000375(RNA splicing, via transesterification reactions);GO:0015030(Cajal body);GO:0000398(mRNA splicing, via spliceosome);GO:0000398(mRNA splicing, via spliceosome)","03040(Spliceosome);03040(Spliceosome)","K12839","NA","survival motor neuron domain containing 1 [Source:HGNC Symbol;Acc:HGNC:16900]",{"v":2.349321788813,"d":"2.35"},{"v":4.41907025881484,"d":"4.42"},{"v":0.531632594916712,"d":"0.53"},{"v":-0.911498534511218,"d":"-0.91"},{"v":0.0762240037866815,"d":"0.08"},{"v":0.589733081928536,"d":"0.59"},"down","no"]
["MSTRG.10410","RBFOX2","MSTRG.10410.1","NA","NA","NA","NA",null,{"v":17.000591,"d":"17.00"},{"v":31.997124,"d":"32.00"},{"v":0.531316220795344,"d":"0.53"},{"v":-0.912357336708831,"d":"-0.91"},{"v":0.0763827985946764,"d":"0.08"},{"v":0.590568202450051,"d":"0.59"},"down","no"]
["MSTRG.8958","IGKV1-27","ENST00000498435","GO:0016020(membrane);GO:0005886(plasma membrane);GO:0005576(extracellular region);GO:0002376(immune system process);GO:0002377(immunoglobulin production);GO:0006955(immune response);GO:0005615(extracellular space);GO:0003823(antigen binding);GO:0002250(adaptive immune response)","NA","NA","NA","immunoglobulin kappa variable 1-27 [Source:HGNC Symbol;Acc:HGNC:5735]",{"v":3.951154,"d":"3.95"},{"v":7.662622,"d":"7.66"},{"v":0.515639946744078,"d":"0.52"},{"v":-0.955564060945011,"d":"-0.96"},{"v":0.0765057408391855,"d":"0.08"},{"v":0.591125195186601,"d":"0.59"},"down","no"]
["MSTRG.1305","PPP1R12B","ENST00000608999;ENST00000465284;ENST00000480184;ENST00000466273;ENST00000391959;ENST00000634903;ENST00000498070;ENST00000434615;ENST00000618451","GO:0019901(protein kinase binding);GO:0005737(cytoplasm);GO:0043085(positive regulation of catalytic activity);GO:0005515(protein binding);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0000086(G2/M transition of mitotic cell cycle);GO:0007165(signal transduction);GO:0030018(Z disc);GO:0031672(A band);GO:0008047(enzyme activator activity);GO:0006937(regulation of muscle contraction);GO:0006937(regulation of muscle contraction)","04510(Focal adhesion);04810(Regulation of actin cytoskeleton);04921(Oxytocin signaling pathway);04270(Vascular smooth muscle contraction);05205(Proteoglycans in cancer);05205(Proteoglycans in cancer)","K12329","NA","protein phosphatase 1 regulatory subunit 12B [Source:HGNC Symbol;Acc:HGNC:7619]",{"v":2.19926313431905,"d":"2.20"},{"v":0.806583934399216,"d":"0.81"},{"v":2.72663890331162,"d":"2.73"},{"v":1.44712365261999,"d":"1.45"},{"v":0.0766576646310171,"d":"0.08"},{"v":0.591905225638299,"d":"0.59"},"up","no"]
["MSTRG.9800","NCOA3","ENST00000372004;ENST00000371998;ENST00000371997;ENST00000497292","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0016740(transferase activity);GO:0003713(transcription coactivator activity);GO:0046983(protein dimerization activity);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0016746(transferase activity, transferring acyl groups);GO:0005515(protein binding);GO:0004402(histone acetyltransferase activity);GO:0016573(histone acetylation);GO:0045893(positive regulation of transcription, DNA-templated);GO:0032870(cellular response to hormone stimulus);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0070062(extracellular exosome);GO:0010628(positive regulation of gene expression);GO:0030374(ligand-dependent nuclear receptor transcription coactivator activity);GO:0035257(nuclear hormone receptor binding);GO:0047485(protein N-terminus binding);GO:0000790(nuclear chromatin);GO:0043234(protein complex);GO:0030521(androgen receptor signaling pathway);GO:0046982(protein heterodimerization activity);GO:0050681(androgen receptor binding);GO:0045618(positive regulation of keratinocyte differentiation);GO:0046966(thyroid hormone receptor binding);GO:0016922(ligand-dependent nuclear receptor binding);GO:0097718(disordered domain specific binding);GO:0071392(cellular response to estradiol stimulus);GO:0030522(intracellular receptor signaling pathway);GO:2001141(regulation of RNA biosynthetic process);GO:0035624(receptor transactivation);GO:0035624(receptor transactivation)","04919(Thyroid hormone signaling pathway);05200(Pathways in cancer);05224(Breast cancer);01522(Endocrine resistance);01522(Endocrine resistance)","K11256","EC:2.3.1.48","nuclear receptor coactivator 3 [Source:HGNC Symbol;Acc:HGNC:7670]",{"v":9.89894366507974,"d":"9.90"},{"v":3.64120185765294,"d":"3.64"},{"v":2.7185923912113,"d":"2.72"},{"v":1.44285985887994,"d":"1.44"},{"v":0.0768105252982574,"d":"0.08"},{"v":0.592247663857114,"d":"0.59"},"up","no"]
["MSTRG.96","NPHP4","ENST00000378156;ENST00000506941;ENST00000470763;ENST00000378161;ENST00000468253;ENST00000460696;ENST00000489180;ENST00000478423;ENST00000466897","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005856(cytoskeleton);GO:0042995(cell projection);GO:0005515(protein binding);GO:0007165(signal transduction);GO:0030054(cell junction);GO:0005813(centrosome);GO:0005815(microtubule organizing center);GO:0090090(negative regulation of canonical Wnt signaling pathway);GO:0005923(bicellular tight junction);GO:0005929(cilium);GO:0005829(cytosol);GO:0097711(ciliary basal body docking);GO:0097730(non-motile cilium);GO:0005911(cell-cell junction);GO:0030036(actin cytoskeleton organization);GO:0035329(hippo signaling);GO:0005198(structural molecule activity);GO:0007632(visual behavior);GO:0016337(single organismal cell-cell adhesion);GO:1903348(positive regulation of bicellular tight junction assembly);GO:0030317(flagellated sperm motility);GO:0035845(photoreceptor cell outer segment organization);GO:0045494(photoreceptor cell maintenance);GO:0060041(retina development in camera-type eye);GO:0032391(photoreceptor connecting cilium);GO:0035869(ciliary transition zone);GO:0036064(ciliary basal body);GO:0097470(ribbon synapse);GO:0097546(ciliary base);GO:0097546(ciliary base)","NA","NA","NA","nephrocystin 4 [Source:HGNC Symbol;Acc:HGNC:19104]",{"v":0.498748582365003,"d":"0.50"},{"v":0.178129497531708,"d":"0.18"},{"v":2.79992134529107,"d":"2.80"},{"v":1.48538629990155,"d":"1.49"},{"v":0.0768377240981046,"d":"0.08"},{"v":0.592247663857114,"d":"0.59"},"up","no"]
["MSTRG.13777","GNG11","ENST00000248564","GO:0016020(membrane);GO:0007186(G-protein coupled receptor signaling pathway);GO:0004871(signal transducer activity);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0007165(signal transduction);GO:0005834(heterotrimeric G-protein complex);GO:0003924(GTPase activity);GO:0071377(cellular response to glucagon stimulus)","04014(Ras signaling pathway);04371(Apelin signaling pathway);04151(PI3K-Akt signaling pathway);04062(Chemokine signaling pathway);04926(Relaxin signaling pathway);04724(Glutamatergic synapse);04727(GABAergic synapse);04725(Cholinergic synapse);04728(Dopaminergic synapse);04726(Serotonergic synapse);04723(Retrograde endocannabinoid signaling);04713(Circadian entrainment);05200(Pathways in cancer);05032(Morphine addiction);05034(Alcoholism);05167(Kaposi's sarcoma-associated herpesvirus infection)","K04546","NA","G protein subunit gamma 11 [Source:HGNC Symbol;Acc:HGNC:4403]",{"v":18.921089,"d":"18.92"},{"v":35.378189,"d":"35.38"},{"v":0.53482356035805,"d":"0.53"},{"v":-0.90286507361648,"d":"-0.90"},{"v":0.0768869798519129,"d":"0.08"},{"v":0.592247663857114,"d":"0.59"},"down","no"]
["MSTRG.4345","TOGARAM1","ENST00000557423;ENST00000557250;ENST00000555607;ENST00000556823;ENST00000361462;ENST00000361577","GO:0005737(cytoplasm);GO:0005856(cytoskeleton);GO:0042995(cell projection);GO:0005874(microtubule);GO:0005929(cilium);GO:0030030(cell projection organization);GO:0036064(ciliary basal body);GO:0031116(positive regulation of microtubule polymerization);GO:0035082(axoneme assembly);GO:1905515(non-motile cilium assembly);GO:1905515(non-motile cilium assembly)","NA","NA","NA","TOG array regulator of axonemal microtubules 1 [Source:HGNC Symbol;Acc:HGNC:19959]",{"v":0.827185356433716,"d":"0.83"},{"v":0.300069947148141,"d":"0.30"},{"v":2.75664179067337,"d":"2.76"},{"v":1.46291180982385,"d":"1.46"},{"v":0.0769158470678112,"d":"0.08"},{"v":0.592247663857114,"d":"0.59"},"up","no"]
["MSTRG.6226","CYBA","ENST00000569359;ENST00000566534;ENST00000261623;ENST00000562209;ENST00000563526;ENST00000566229;ENST00000568278;ENST00000567174;ENST00000565588;ENST00000561972","GO:0016020(membrane);GO:0046872(metal ion binding);GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0020037(heme binding);GO:0005789(endoplasmic reticulum membrane);GO:0002479(antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent);GO:0043312(neutrophil degranulation);GO:0035579(specific granule membrane);GO:0070821(tertiary granule membrane);GO:0046982(protein heterodimerization activity);GO:0030670(phagocytic vesicle membrane);GO:0045087(innate immune response);GO:0050766(positive regulation of phagocytosis);GO:0048010(vascular endothelial growth factor receptor signaling pathway);GO:0006954(inflammatory response);GO:0009055(electron carrier activity);GO:0034599(cellular response to oxidative stress);GO:0017124(SH3 domain binding);GO:0032760(positive regulation of tumor necrosis factor production);GO:0006801(superoxide metabolic process);GO:0016175(superoxide-generating NADPH oxidase activity);GO:0042554(superoxide anion generation);GO:0045454(cell redox homeostasis);GO:0045730(respiratory burst);GO:0043020(NADPH oxidase complex);GO:0030141(secretory granule);GO:0001666(response to hypoxia);GO:0001938(positive regulation of endothelial cell proliferation);GO:0003106(negative regulation of glomerular filtration by angiotensin);GO:0008217(regulation of blood pressure);GO:0014823(response to activity);GO:0014895(smooth muscle hypertrophy);GO:0017004(cytochrome complex assembly);GO:0030307(positive regulation of cell growth);GO:0031667(response to nutrient levels);GO:0032755(positive regulation of interleukin-6 production);GO:0032930(positive regulation of superoxide anion generation);GO:0033864(positive regulation of NAD(P)H oxidase activity);GO:0034137(positive regulation of toll-like receptor 2 signaling pathway);GO:0042493(response to drug);GO:0048661(positive regulation of smooth muscle cell proliferation);GO:0050665(hydrogen peroxide biosynthetic process);GO:0051279(regulation of release of sequestered calcium ion into cytosol);GO:0070257(positive regulation of mucus secretion);GO:0070555(response to interleukin-1);GO:0071230(cellular response to amino acid stimulus);GO:0071260(cellular response to mechanical stimulus);GO:0071310(cellular response to organic substance);GO:0071333(cellular response to glucose stimulus);GO:0071356(cellular response to tumor necrosis factor);GO:0071407(cellular response to organic cyclic compound);GO:0071480(cellular response to gamma radiation);GO:0072593(reactive oxygen species metabolic process);GO:1900426(positive regulation of defense response to bacterium);GO:1903428(positive regulation of reactive oxygen species biosynthetic process);GO:1904044(response to aldosterone);GO:1904385(cellular response to angiotensin);GO:1904845(cellular response to L-glutamine);GO:0001725(stress fiber);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005739(mitochondrion);GO:0005768(endosome);GO:0005794(Golgi apparatus);GO:0005925(focal adhesion);GO:0016324(apical plasma membrane);GO:0030425(dendrite);GO:0043025(neuronal cell body);GO:0097038(perinuclear endoplasmic reticulum);GO:0016021(integral component of membrane);GO:0016021(integral component of membrane)","04145(Phagosome);04621(NOD-like receptor signaling pathway);04670(Leukocyte transendothelial migration);04380(Osteoclast differentiation);05418(Fluid shear stress and atherosclerosis);05140(Leishmaniasis);05140(Leishmaniasis)","K08009","NA","cytochrome b-245 alpha chain [Source:HGNC Symbol;Acc:HGNC:2577]",{"v":84.5187457879059,"d":"84.52"},{"v":157.88496174084,"d":"157.88"},{"v":0.535318531011453,"d":"0.54"},{"v":-0.901530499892615,"d":"-0.90"},{"v":0.0770169101343358,"d":"0.08"},{"v":0.592247663857114,"d":"0.59"},"down","no"]
["ENSG00000103043","VAC14","ENST00000261776;ENST00000566655;ENST00000536184;ENST00000564512;ENST00000564685;ENST00000568886;ENST00000566416;ENST00000568548;ENST00000563662;ENST00000571759;ENST00000561879","GO:0043550(regulation of lipid kinase activity);GO:0070772(PAS complex);GO:0016020(membrane);GO:0005783(endoplasmic reticulum);GO:0005515(protein binding);GO:0007165(signal transduction);GO:0005768(endosome);GO:0043231(intracellular membrane-bounded organelle);GO:0004872(receptor activity);GO:0010008(endosome membrane);GO:0016032(viral process);GO:0031090(organelle membrane);GO:0006661(phosphatidylinositol biosynthetic process);GO:0000139(Golgi membrane);GO:0031901(early endosome membrane);GO:0031902(late endosome membrane);GO:0031902(late endosome membrane)","05203(Viral carcinogenesis);05166(HTLV-I infection);05166(HTLV-I infection)","K15305","NA","Vac14, PIKFYVE complex component [Source:HGNC Symbol;Acc:HGNC:25507]",{"v":2.2982887318753,"d":"2.30"},{"v":0.84317882878202,"d":"0.84"},{"v":2.72574293070807,"d":"2.73"},{"v":1.44664950562042,"d":"1.45"},{"v":0.0770556315685313,"d":"0.08"},{"v":0.592247663857114,"d":"0.59"},"up","no"]
["MSTRG.6398","ZBTB4","ENST00000380599;MSTRG.6398.3;ENST00000311403","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0005694(chromosome);GO:0042803(protein homodimerization activity);GO:0006974(cellular response to DNA damage stimulus);GO:0016604(nuclear body);GO:0005515(protein binding);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0019901(protein kinase binding);GO:0043565(sequence-specific DNA binding);GO:0045892(negative regulation of transcription, DNA-templated);GO:0000977(RNA polymerase II regulatory region sequence-specific DNA binding);GO:0008327(methyl-CpG binding);GO:0001227(transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding);GO:0010428(methyl-CpNpG binding);GO:0010428(methyl-CpNpG binding)","NA","NA","NA","zinc finger and BTB domain containing 4 [Source:HGNC Symbol;Acc:HGNC:23847]",{"v":1.63902588123285,"d":"1.64"},{"v":0.598929050185574,"d":"0.60"},{"v":2.73659439415238,"d":"2.74"},{"v":1.45238162070649,"d":"1.45"},{"v":0.0770815608807068,"d":"0.08"},{"v":0.592247663857114,"d":"0.59"},"up","no"]
["ENSG00000234449","FAM239A","ENST00000381108;ENST00000456563;ENST00000438107","NA","NA","NA","NA","family with sequence similarity 239 member A (non-protein coding) [Source:HGNC Symbol;Acc:HGNC:53414]",{"v":0.493216884957772,"d":"0.49"},{"v":0.167659892490299,"d":"0.17"},{"v":2.94177025663016,"d":"2.94"},{"v":1.55668458086786,"d":"1.56"},{"v":0.0771100032508359,"d":"0.08"},{"v":0.592247663857114,"d":"0.59"},"up","no"]
["ENSG00000182378","PLCXD1","ENST00000381657;ENST00000448477;ENST00000430923;ENST00000399012;ENST00000447472;ENST00000443019;ENST00000484611","GO:0005737(cytoplasm);GO:0006629(lipid metabolic process);GO:0008081(phosphoric diester hydrolase activity);GO:0008081(phosphoric diester hydrolase activity)","NA","NA","NA","phosphatidylinositol specific phospholipase C X domain containing 1 [Source:HGNC Symbol;Acc:HGNC:23148]",{"v":1.0656575889194,"d":"1.07"},{"v":0.389314849943466,"d":"0.39"},{"v":2.73726416825392,"d":"2.74"},{"v":1.45273467322643,"d":"1.45"},{"v":0.0772157317706596,"d":"0.08"},{"v":0.592667741607846,"d":"0.59"},"up","no"]
["ENSG00000138670","RASGEF1B","ENST00000264400;ENST00000436139;ENST00000512716;ENST00000509081;ENST00000638048;ENST00000507538;ENST00000335927","GO:0007264(small GTPase mediated signal transduction);GO:0043547(positive regulation of GTPase activity);GO:0005085(guanyl-nucleotide exchange factor activity);GO:0030496(midbody);GO:0005768(endosome);GO:0005769(early endosome);GO:0005770(late endosome);GO:0005088(Ras guanyl-nucleotide exchange factor activity);GO:0005622(intracellular);GO:0005622(intracellular)","NA","NA","NA","RasGEF domain family member 1B [Source:HGNC Symbol;Acc:HGNC:24881]",{"v":0.339083297554748,"d":"0.34"},{"v":0.646221509476579,"d":"0.65"},{"v":0.52471682322892,"d":"0.52"},{"v":-0.930389049141725,"d":"-0.93"},{"v":0.0773687916140573,"d":"0.08"},{"v":0.593450315068723,"d":"0.59"},"down","no"]
["MSTRG.12017","PTGER4","ENST00000302472;ENST00000513635;ENST00000509543","GO:0005622(intracellular);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0004930(G-protein coupled receptor activity);GO:0007186(G-protein coupled receptor signaling pathway);GO:0005886(plasma membrane);GO:0004871(signal transducer activity);GO:0007165(signal transduction);GO:0006955(immune response);GO:0004955(prostaglandin receptor activity);GO:0004957(prostaglandin E receptor activity);GO:0005515(protein binding);GO:0060348(bone development);GO:0050728(negative regulation of inflammatory response);GO:0070371(ERK1 and ERK2 cascade);GO:0071260(cellular response to mechanical stimulus);GO:0050729(positive regulation of inflammatory response);GO:0007254(JNK cascade);GO:0051492(regulation of stress fiber assembly);GO:0050715(positive regulation of cytokine secretion);GO:0009612(response to mechanical stimulus);GO:0050710(negative regulation of cytokine secretion);GO:0007188(adenylate cyclase-modulating G-protein coupled receptor signaling pathway);GO:0042093(T-helper cell differentiation);GO:0030278(regulation of ossification);GO:0032496(response to lipopolysaccharide);GO:0033624(negative regulation of integrin activation);GO:0071380(cellular response to prostaglandin E stimulus);GO:2000420(negative regulation of eosinophil extravasation);GO:2000420(negative regulation of eosinophil extravasation)","04080(Neuroactive ligand-receptor interaction);04924(Renin secretion);04750(Inflammatory mediator regulation of TRP channels);05200(Pathways in cancer);05165(Human papillomavirus infection);05165(Human papillomavirus infection)","K04261","NA","prostaglandin E receptor 4 [Source:HGNC Symbol;Acc:HGNC:9596]",{"v":6.07000549406716,"d":"6.07"},{"v":2.22939763620298,"d":"2.23"},{"v":2.72271101193296,"d":"2.72"},{"v":1.44504386311017,"d":"1.45"},{"v":0.0775479393236472,"d":"0.08"},{"v":0.594431827964036,"d":"0.59"},"up","no"]
["MSTRG.11870","AC139713.2;GUSBP5","ENST00000514475;ENST00000641741;ENST00000642059;ENST00000510536;ENST00000641328;ENST00000641428;ENST00000510805;ENST00000641556;ENST00000506982;ENST00000499587;ENST00000509873","NA","NA","NA","NA","glucuronidase, beta pseudogene 5 [Source:HGNC Symbol;Acc:HGNC:42319]",{"v":0.0539228585800928,"d":"0.05"},{"v":0.111250037887977,"d":"0.11"},{"v":0.484699687333053,"d":"0.48"},{"v":-1.04483694302716,"d":"-1.04"},{"v":0.0776890072472104,"d":"0.08"},{"v":0.595120343774311,"d":"0.60"},"down","no"]
["MSTRG.4139","APEX1","ENST00000216714;ENST00000398030;ENST00000555414;ENST00000553555;ENST00000557159;ENST00000553681;ENST00000556054;ENST00000438886;ENST00000557150;ENST00000557365;ENST00000554325;ENST00000555306;ENST00000557181;ENST00000555839;ENST00000557054;ENST00000557344","GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016607(nuclear speck);GO:0046872(metal ion binding);GO:0016491(oxidoreductase activity);GO:0016787(hydrolase activity);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0016829(lyase activity);GO:0005622(intracellular);GO:0005840(ribosome);GO:0031490(chromatin DNA binding);GO:0005783(endoplasmic reticulum);GO:0005813(centrosome);GO:0005739(mitochondrion);GO:0055114(oxidation-reduction process);GO:0004519(endonuclease activity);GO:0006281(DNA repair);GO:0090305(nucleic acid phosphodiester bond hydrolysis);GO:0005515(protein binding);GO:0006310(DNA recombination);GO:0006974(cellular response to DNA damage stimulus);GO:0090502(RNA phosphodiester bond hydrolysis, endonucleolytic);GO:0004527(exonuclease activity);GO:0048471(perinuclear region of cytoplasm);GO:0004518(nuclease activity);GO:0003713(transcription coactivator activity);GO:0005654(nucleoplasm);GO:0005730(nucleolus);GO:1903507(negative regulation of nucleic acid-templated transcription);GO:0003906(DNA-(apurinic or apyrimidinic site) lyase activity);GO:0000784(nuclear chromosome, telomeric region);GO:0004523(RNA-DNA hybrid ribonuclease activity);GO:0042981(regulation of apoptotic process);GO:0003714(transcription corepressor activity);GO:0004528(phosphodiesterase I activity);GO:0003684(damaged DNA binding);GO:0080111(DNA demethylation);GO:0008408(3'-5' exonuclease activity);GO:0004520(endodeoxyribonuclease activity);GO:0006286(base-excision repair, base-free sugar-phosphate removal);GO:0000723(telomere maintenance);GO:0003691(double-stranded telomeric DNA binding);GO:0004844(uracil DNA N-glycosylase activity);GO:0008081(phosphoric diester hydrolase activity);GO:0008309(double-stranded DNA exodeoxyribonuclease activity);GO:0008311(double-stranded DNA 3'-5' exodeoxyribonuclease activity);GO:0016890(site-specific endodeoxyribonuclease activity, specific for altered base);GO:0006284(base-excision repair);GO:0043488(regulation of mRNA stability);GO:0097698(telomere maintenance via base-excision repair);GO:0004521(endoribonuclease activity);GO:0032403(protein complex binding);GO:0051059(NF-kappaB binding);GO:0007568(aging);GO:0010243(response to organonitrogen compound);GO:0014912(negative regulation of smooth muscle cell migration);GO:0042493(response to drug);GO:0045454(cell redox homeostasis);GO:0070301(cellular response to hydrogen peroxide);GO:0071320(cellular response to cAMP);GO:0071375(cellular response to peptide hormone stimulus);GO:0071417(cellular response to organonitrogen compound);GO:1900087(positive regulation of G1/S transition of mitotic cell cycle);GO:0005667(transcription factor complex);GO:0005667(transcription factor complex)","03410(Base excision repair);03410(Base excision repair)","K10771","EC:4.2.99.18","apurinic/apyrimidinic endodeoxyribonuclease 1 [Source:HGNC Symbol;Acc:HGNC:587]",{"v":17.4231486373277,"d":"17.42"},{"v":32.5494336495228,"d":"32.55"},{"v":0.53528269723314,"d":"0.54"},{"v":-0.901627075934045,"d":"-0.90"},{"v":0.0777750887799828,"d":"0.08"},{"v":0.595231438012224,"d":"0.60"},"down","no"]
["MSTRG.8877","RNF181","ENST00000306368;ENST00000443647;ENST00000461845;ENST00000456023;ENST00000441634","GO:0046872(metal ion binding);GO:0016740(transferase activity);GO:0016567(protein ubiquitination);GO:0061630(ubiquitin protein ligase activity);GO:0043161(proteasome-mediated ubiquitin-dependent protein catabolic process);GO:0005737(cytoplasm);GO:0042787(protein ubiquitination involved in ubiquitin-dependent protein catabolic process);GO:0000209(protein polyubiquitination);GO:0004842(ubiquitin-protein transferase activity);GO:0051865(protein autoubiquitination);GO:0051865(protein autoubiquitination)","NA","NA","NA","ring finger protein 181 [Source:HGNC Symbol;Acc:HGNC:28037]",{"v":12.1373243786885,"d":"12.14"},{"v":22.7039889581967,"d":"22.70"},{"v":0.534589952498485,"d":"0.53"},{"v":-0.903495372190075,"d":"-0.90"},{"v":0.0778060210886554,"d":"0.08"},{"v":0.595231438012224,"d":"0.60"},"down","no"]
["MSTRG.2399","AP002358.2","ENST00000532980","NA","NA","NA","NA",null,{"v":1.756068,"d":"1.76"},{"v":0.62422,"d":"0.62"},{"v":2.81321969818333,"d":"2.81"},{"v":1.49222222421425,"d":"1.49"},{"v":0.0778693580183288,"d":"0.08"},{"v":0.595323801623998,"d":"0.60"},"up","no"]
["ENSG00000197016","ZNF470","ENST00000330619;ENST00000391709;ENST00000601059","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0005654(nucleoplasm);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0005622(intracellular);GO:0016604(nuclear body);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding)","NA","NA","NA","zinc finger protein 470 [Source:HGNC Symbol;Acc:HGNC:22220]",{"v":0.51207653298016,"d":"0.51"},{"v":0.18353544219383,"d":"0.18"},{"v":2.79006891998201,"d":"2.79"},{"v":1.48030075979217,"d":"1.48"},{"v":0.0779752523819059,"d":"0.08"},{"v":0.595563140507563,"d":"0.60"},"up","no"]
["MSTRG.4638","IFI27L2","ENST00000238609;ENST00000556552;ENST00000555558;ENST00000553601;ENST00000554909","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016021(integral component of membrane)","NA","NA","NA","interferon alpha inducible protein 27 like 2 [Source:HGNC Symbol;Acc:HGNC:19753]",{"v":1.55673256979543,"d":"1.56"},{"v":2.97960550541516,"d":"2.98"},{"v":0.522462643784961,"d":"0.52"},{"v":-0.93660020707727,"d":"-0.94"},{"v":0.0780521991135787,"d":"0.08"},{"v":0.595563140507563,"d":"0.60"},"down","no"]
["ENSG00000092148","HECTD1","ENST00000553700;ENST00000399332;ENST00000554027;ENST00000556281;ENST00000554882;ENST00000555311;ENST00000556224;ENST00000556004;ENST00000557321;ENST00000557695;ENST00000555843;ENST00000554471;ENST00000554850;ENST00000553957;ENST00000553616","GO:0016740(transferase activity);GO:0016567(protein ubiquitination);GO:0004842(ubiquitin-protein transferase activity);GO:0046872(metal ion binding);GO:0005737(cytoplasm);GO:0061630(ubiquitin protein ligase activity);GO:0005515(protein binding);GO:0005515(protein binding)","NA","NA","NA","HECT domain E3 ubiquitin protein ligase 1 [Source:HGNC Symbol;Acc:HGNC:20157]",{"v":5.69643085292244,"d":"5.70"},{"v":2.10032983986304,"d":"2.10"},{"v":2.71216013066495,"d":"2.71"},{"v":1.43944236022064,"d":"1.44"},{"v":0.0781463673306997,"d":"0.08"},{"v":0.595563140507563,"d":"0.60"},"up","no"]
["MSTRG.5472","HBQ1","ENST00000199708","GO:0006810(transport);GO:0046872(metal ion binding);GO:0005506(iron ion binding);GO:0005515(protein binding);GO:0020037(heme binding);GO:0005344(oxygen transporter activity);GO:0019825(oxygen binding);GO:0015671(oxygen transport);GO:0005833(hemoglobin complex)","NA","NA","NA","hemoglobin subunit theta 1 [Source:HGNC Symbol;Acc:HGNC:4833]",{"v":33.239902,"d":"33.24"},{"v":62.054848,"d":"62.05"},{"v":0.535653588257923,"d":"0.54"},{"v":-0.900627795825964,"d":"-0.90"},{"v":0.078156621612757,"d":"0.08"},{"v":0.595563140507563,"d":"0.60"},"down","no"]
["MSTRG.11096","RPL24","ENST00000464595;ENST00000394077;ENST00000469605;ENST00000470961;ENST00000495401;ENST00000488288","GO:0005737(cytoplasm);GO:0003723(RNA binding);GO:0016020(membrane);GO:0006412(translation);GO:0030529(intracellular ribonucleoprotein complex);GO:0005840(ribosome);GO:0003735(structural constituent of ribosome);GO:0000027(ribosomal large subunit assembly);GO:0005829(cytosol);GO:0045296(cadherin binding);GO:0070062(extracellular exosome);GO:0005515(protein binding);GO:0006413(translational initiation);GO:0006364(rRNA processing);GO:0000184(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay);GO:0019083(viral transcription);GO:0006614(SRP-dependent cotranslational protein targeting to membrane);GO:0022625(cytosolic large ribosomal subunit);GO:1902626(assembly of large subunit precursor of preribosome);GO:0007093(mitotic cell cycle checkpoint);GO:0010458(exit from mitosis);GO:0021554(optic nerve development);GO:0031290(retinal ganglion cell axon guidance);GO:0060041(retina development in camera-type eye);GO:0060041(retina development in camera-type eye)","03010(Ribosome);03010(Ribosome)","K02896","NA","ribosomal protein L24 [Source:HGNC Symbol;Acc:HGNC:10325]",{"v":74.0010287378822,"d":"74.00"},{"v":137.796841563758,"d":"137.80"},{"v":0.537029934054347,"d":"0.54"},{"v":-0.896925588598181,"d":"-0.90"},{"v":0.0781570848302356,"d":"0.08"},{"v":0.595563140507563,"d":"0.60"},"down","no"]
["ENSG00000178429","RPS3AP5","ENST00000389400","NA","NA","NA","NA","ribosomal protein S3A pseudogene 5 [Source:HGNC Symbol;Acc:HGNC:23744]",{"v":1.730529,"d":"1.73"},{"v":3.322118,"d":"3.32"},{"v":0.520911358356326,"d":"0.52"},{"v":-0.940890199811247,"d":"-0.94"},{"v":0.0783321444322653,"d":"0.08"},{"v":0.596490766879607,"d":"0.60"},"down","no"]
["MSTRG.4609","CCDC88C","MSTRG.4609.1;ENST00000553403;ENST00000389857;ENST00000334448;ENST00000553437;ENST00000554165;ENST00000557507;ENST00000554051;ENST00000389856;ENST00000554872;ENST00000556767;ENST00000555995;ENST00000557455","GO:0016055(Wnt signaling pathway);GO:0005737(cytoplasm);GO:0005813(centrosome);GO:0031648(protein destabilization);GO:0008017(microtubule binding);GO:0051959(dynein light intermediate chain binding);GO:0030705(cytoskeleton-dependent intracellular transport);GO:0031122(cytoplasmic microtubule organization);GO:0030165(PDZ domain binding);GO:0043621(protein self-association);GO:0001932(regulation of protein phosphorylation);GO:0051260(protein homooligomerization);GO:0031098(stress-activated protein kinase signaling cascade);GO:0031098(stress-activated protein kinase signaling cascade)","NA","NA","NA","coiled-coil domain containing 88C [Source:HGNC Symbol;Acc:HGNC:19967]",{"v":9.13195157017544,"d":"9.13"},{"v":3.37381959922743,"d":"3.37"},{"v":2.70671009566325,"d":"2.71"},{"v":1.43654037482797,"d":"1.44"},{"v":0.0783815474260122,"d":"0.08"},{"v":0.596490766879607,"d":"0.60"},"up","no"]
["MSTRG.9935","FP671120.4","ENST00000629969","NA","NA","NA","NA",null,{"v":50.066967,"d":"50.07"},{"v":93.243622,"d":"93.24"},{"v":0.536947899771633,"d":"0.54"},{"v":-0.897145985052106,"d":"-0.90"},{"v":0.0784497073578584,"d":"0.08"},{"v":0.596618501340412,"d":"0.60"},"down","no"]
["ENSG00000162927","PUS10","ENST00000398658;ENST00000316752;ENST00000602599;ENST00000421319;ENST00000430495","GO:0003723(RNA binding);GO:0016853(isomerase activity);GO:0008033(tRNA processing);GO:0009982(pseudouridine synthase activity);GO:0001522(pseudouridine synthesis);GO:0009451(RNA modification);GO:0031119(tRNA pseudouridine synthesis);GO:0031119(tRNA pseudouridine synthesis)","NA","NA","NA","pseudouridylate synthase 10 [Source:HGNC Symbol;Acc:HGNC:26505]",{"v":0.266659804077898,"d":"0.27"},{"v":0.511901903542021,"d":"0.51"},{"v":0.520919735271132,"d":"0.52"},{"v":-0.94086699963317,"d":"-0.94"},{"v":0.0785344468982967,"d":"0.08"},{"v":0.596728949330218,"d":"0.60"},"down","no"]
["ENSG00000158636","EMSY","ENST00000525919;ENST00000532719;ENST00000534573;ENST00000533988;ENST00000427574;ENST00000524451;ENST00000531793;ENST00000334736;ENST00000529032;ENST00000531641;ENST00000528826;ENST00000525038;ENST00000524767","GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0016569(covalent chromatin modification);GO:0005515(protein binding);GO:0006281(DNA repair);GO:0006974(cellular response to DNA damage stimulus);GO:0042803(protein homodimerization activity);GO:0042803(protein homodimerization activity)","NA","NA","NA","EMSY, BRCA2 interacting transcriptional repressor [Source:HGNC Symbol;Acc:HGNC:18071]",{"v":1.73787116761436,"d":"1.74"},{"v":0.639972639904948,"d":"0.64"},{"v":2.71553978912673,"d":"2.72"},{"v":1.44123900233605,"d":"1.44"},{"v":0.0785977281110435,"d":"0.08"},{"v":0.596728949330218,"d":"0.60"},"up","no"]
["MSTRG.6040","PSMB10;AC040162.1;CTRL","ENST00000570304;ENST00000358514;ENST00000575231;ENST00000570985;ENST00000571605;ENST00000573493;ENST00000575302;ENST00000576915;ENST00000574576;ENST00000575556;ENST00000571044;ENST00000574481;ENST00000572144","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016787(hydrolase activity);GO:0005515(protein binding);GO:0008233(peptidase activity);GO:0006508(proteolysis);GO:0000502(proteasome complex);GO:0004175(endopeptidase activity);GO:0004298(threonine-type endopeptidase activity);GO:0051603(proteolysis involved in cellular protein catabolic process);GO:0005839(proteasome core complex);GO:0038095(Fc-epsilon receptor signaling pathway);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0000165(MAPK cascade);GO:0000209(protein polyubiquitination);GO:0002223(stimulatory C-type lectin receptor signaling pathway);GO:0002479(antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent);GO:0006521(regulation of cellular amino acid metabolic process);GO:0010972(negative regulation of G2/M transition of mitotic cell cycle);GO:0016579(protein deubiquitination);GO:0031145(anaphase-promoting complex-dependent catabolic process);GO:0031146(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process);GO:0033209(tumor necrosis factor-mediated signaling pathway);GO:0038061(NIK/NF-kappaB signaling);GO:0043161(proteasome-mediated ubiquitin-dependent protein catabolic process);GO:0043488(regulation of mRNA stability);GO:0043687(post-translational protein modification);GO:0050852(T cell receptor signaling pathway);GO:0051437(positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition);GO:0055085(transmembrane transport);GO:0060071(Wnt signaling pathway, planar cell polarity pathway);GO:0061418(regulation of transcription from RNA polymerase II promoter in response to hypoxia);GO:0090090(negative regulation of canonical Wnt signaling pathway);GO:0090263(positive regulation of canonical Wnt signaling pathway);GO:1902036(regulation of hematopoietic stem cell differentiation);GO:0019774(proteasome core complex, beta-subunit complex);GO:0016032(viral process);GO:0002376(immune system process);GO:0051436(negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle);GO:0006959(humoral immune response);GO:1990111(spermatoproteasome complex);GO:0004252(serine-type endopeptidase activity);GO:0008236(serine-type peptidase activity);GO:0005615(extracellular space);GO:0007586(digestion);GO:0007586(digestion)","03050(Proteasome);04972(Pancreatic secretion);04974(Protein digestion and absorption);04974(Protein digestion and absorption)","K02733;K09632","EC:3.4.25.1;EC:3.4.21.-","proteasome subunit beta 10 [Source:HGNC Symbol;Acc:HGNC:9538];chymotrypsin like [Source:HGNC Symbol;Acc:HGNC:2524]",{"v":8.52221001617139,"d":"8.52"},{"v":15.8701333036628,"d":"15.87"},{"v":0.53699675063249,"d":"0.54"},{"v":-0.897014736398416,"d":"-0.90"},{"v":0.0786955491685684,"d":"0.08"},{"v":0.596728949330218,"d":"0.60"},"down","no"]
["ENSG00000100346","CACNA1I","ENST00000402142","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0055085(transmembrane transport);GO:0005216(ion channel activity);GO:0006811(ion transport);GO:0030317(flagellated sperm motility);GO:0005244(voltage-gated ion channel activity);GO:0034765(regulation of ion transmembrane transport);GO:0005515(protein binding);GO:0035725(sodium ion transmembrane transport);GO:0006816(calcium ion transport);GO:0070588(calcium ion transmembrane transport);GO:0005245(voltage-gated calcium channel activity);GO:0005262(calcium channel activity);GO:0005891(voltage-gated calcium channel complex);GO:0060078(regulation of postsynaptic membrane potential);GO:0008332(low voltage-gated calcium channel activity);GO:0070509(calcium ion import);GO:0005886(plasma membrane);GO:0007165(signal transduction);GO:0086010(membrane depolarization during action potential);GO:0005248(voltage-gated sodium channel activity);GO:0019228(neuronal action potential);GO:0045956(positive regulation of calcium ion-dependent exocytosis);GO:0030431(sleep)","04010(MAPK signaling pathway);04020(Calcium signaling pathway);04925(Aldosterone synthesis and secretion);04927(Cortisol synthesis and secretion);04713(Circadian entrainment)","K04856","NA","calcium voltage-gated channel subunit alpha1 I [Source:HGNC Symbol;Acc:HGNC:1396]",{"v":0.539973130467013,"d":"0.54"},{"v":0.194874063750927,"d":"0.19"},{"v":2.77088248725169,"d":"2.77"},{"v":1.47034552761682,"d":"1.47"},{"v":0.0787247986811544,"d":"0.08"},{"v":0.596728949330218,"d":"0.60"},"up","no"]
["MSTRG.9713","ROMO1","ENST00000374077;ENST00000374078;ENST00000374072;ENST00000336695","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005743(mitochondrial inner membrane);GO:0005739(mitochondrion);GO:0042742(defense response to bacterium);GO:0003674(molecular_function);GO:0050829(defense response to Gram-negative bacterium);GO:2000379(positive regulation of reactive oxygen species metabolic process);GO:0050830(defense response to Gram-positive bacterium);GO:0061844(antimicrobial humoral immune response mediated by antimicrobial peptide);GO:0008284(positive regulation of cell proliferation);GO:0031640(killing of cells of other organism);GO:0051715(cytolysis in other organism);GO:0034614(cellular response to reactive oxygen species);GO:0001302(replicative cell aging);GO:0001302(replicative cell aging)","NA","NA","NA","reactive oxygen species modulator 1 [Source:HGNC Symbol;Acc:HGNC:16185]",{"v":8.80293752421652,"d":"8.80"},{"v":16.5340610883191,"d":"16.53"},{"v":0.532412301925966,"d":"0.53"},{"v":-0.909384188320988,"d":"-0.91"},{"v":0.0788125691580576,"d":"0.08"},{"v":0.596728949330218,"d":"0.60"},"down","no"]
["ENSG00000178177","LCORL","ENST00000326877;ENST00000635767;ENST00000512376;ENST00000510451;ENST00000382226;ENST00000382224;ENST00000510121","GO:0005634(nucleus);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0006366(transcription from RNA polymerase II promoter);GO:0006366(transcription from RNA polymerase II promoter)","NA","NA","NA","ligand dependent nuclear receptor corepressor like [Source:HGNC Symbol;Acc:HGNC:30776]",{"v":0.676700710728227,"d":"0.68"},{"v":0.247518932292368,"d":"0.25"},{"v":2.73393515583249,"d":"2.73"},{"v":1.45097902514283,"d":"1.45"},{"v":0.0788303110403462,"d":"0.08"},{"v":0.596728949330218,"d":"0.60"},"up","no"]
["MSTRG.4126","CCNB1IP1","ENST00000358932;ENST00000353689;ENST00000553516;ENST00000437553;ENST00000555348;ENST00000554184;ENST00000556854;ENST00000398163;ENST00000554047;ENST00000557665","GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0016740(transferase activity);GO:0016567(protein ubiquitination);GO:0005694(chromosome);GO:0005515(protein binding);GO:0051321(meiotic cell cycle);GO:0061630(ubiquitin protein ligase activity);GO:0007131(reciprocal meiotic recombination);GO:0000795(synaptonemal complex);GO:0051026(chiasma assembly);GO:0001825(blastocyst formation);GO:0007286(spermatid development);GO:0000794(condensed nuclear chromosome);GO:0000794(condensed nuclear chromosome)","NA","NA","NA","cyclin B1 interacting protein 1 [Source:HGNC Symbol;Acc:HGNC:19437]",{"v":2.21258499076087,"d":"2.21"},{"v":4.14393199782609,"d":"4.14"},{"v":0.533933711248542,"d":"0.53"},{"v":-0.905267454827224,"d":"-0.91"},{"v":0.0788338589152293,"d":"0.08"},{"v":0.596728949330218,"d":"0.60"},"down","no"]
["MSTRG.6678","MYO1D","ENST00000318217;ENST00000577352;ENST00000582217;ENST00000579584;ENST00000580538","GO:0005829(cytosol);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0003774(motor activity);GO:0016459(myosin complex);GO:0003779(actin binding);GO:0031410(cytoplasmic vesicle);GO:0005516(calmodulin binding);GO:0005768(endosome);GO:0030424(axon);GO:0051015(actin filament binding);GO:0070062(extracellular exosome);GO:0016323(basolateral plasma membrane);GO:0010923(negative regulation of phosphatase activity);GO:0005903(brush border);GO:0043005(neuron projection);GO:0019904(protein domain specific binding);GO:0043025(neuronal cell body);GO:0097440(apical dendrite);GO:0000146(microfilament motor activity);GO:0030898(actin-dependent ATPase activity);GO:0048306(calcium-dependent protein binding);GO:0030900(forebrain development);GO:0051641(cellular localization);GO:0061502(early endosome to recycling endosome transport);GO:0005790(smooth endoplasmic reticulum);GO:0030673(axolemma);GO:0043209(myelin sheath);GO:0044853(plasma membrane raft);GO:0044853(plasma membrane raft)","NA","NA","NA","myosin ID [Source:HGNC Symbol;Acc:HGNC:7598]",{"v":0.550441533341475,"d":"0.55"},{"v":0.1978979555447,"d":"0.20"},{"v":2.78144123230795,"d":"2.78"},{"v":1.47583262392568,"d":"1.48"},{"v":0.0788773698590244,"d":"0.08"},{"v":0.596728949330218,"d":"0.60"},"up","no"]
["MSTRG.15164","WWC3","ENST00000380861;ENST00000466248","GO:0032947(protein complex scaffold);GO:0005829(cytosol);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0019900(kinase binding);GO:0046621(negative regulation of organ growth);GO:0035331(negative regulation of hippo signaling);GO:0035331(negative regulation of hippo signaling)","NA","NA","NA","WWC family member 3 [Source:HGNC Symbol;Acc:HGNC:29237]",{"v":9.48276825695811,"d":"9.48"},{"v":3.50643284607816,"d":"3.51"},{"v":2.70439180592445,"d":"2.70"},{"v":1.43530418102679,"d":"1.44"},{"v":0.078940141228069,"d":"0.08"},{"v":0.596728949330218,"d":"0.60"},"up","no"]
["ENSG00000162928","PEX13","ENST00000295030;ENST00000472678;ENST00000444100;ENST00000401576","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0015031(protein transport);GO:0043231(intracellular membrane-bounded organelle);GO:0005515(protein binding);GO:0005777(peroxisome);GO:0005778(peroxisomal membrane);GO:0016560(protein import into peroxisome matrix, docking);GO:0005779(integral component of peroxisomal membrane);GO:0001561(fatty acid alpha-oxidation);GO:0001764(neuron migration);GO:0007626(locomotory behavior);GO:0060152(microtubule-based peroxisome localization);GO:0021795(cerebral cortex cell migration);GO:0001967(suckling behavior);GO:0001967(suckling behavior)","04146(Peroxisome);04146(Peroxisome)","K13344","NA","peroxisomal biogenesis factor 13 [Source:HGNC Symbol;Acc:HGNC:8855]",{"v":0.671404749915398,"d":"0.67"},{"v":1.26924082707276,"d":"1.27"},{"v":0.528981368700417,"d":"0.53"},{"v":-0.918711184942895,"d":"-0.92"},{"v":0.0790167050816155,"d":"0.08"},{"v":0.596728949330218,"d":"0.60"},"down","no"]
["ENSG00000166963","MAP1A","ENST00000300231;ENST00000382031","GO:0008017(microtubule binding);GO:0000226(microtubule cytoskeleton organization);GO:0005874(microtubule);GO:0005737(cytoplasm);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0005875(microtubule associated complex);GO:0005198(structural molecule activity);GO:0005198(structural molecule activity)","NA","NA","NA","microtubule associated protein 1A [Source:HGNC Symbol;Acc:HGNC:6835]",{"v":0.650833718129645,"d":"0.65"},{"v":0.236467950700913,"d":"0.24"},{"v":2.7523125912011,"d":"2.75"},{"v":1.46064433201866,"d":"1.46"},{"v":0.0790294604382912,"d":"0.08"},{"v":0.596728949330218,"d":"0.60"},"up","no"]
["MSTRG.2427","MS4A1","ENST00000532073;MSTRG.2427.3;ENST00000345732;ENST00000532418;ENST00000528313;ENST00000532491;ENST00000527101;ENST00000524807;ENST00000534668;ENST00000533306;ENST00000530482;ENST00000389939;ENST00000534503","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005887(integral component of plasma membrane);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0005615(extracellular space);GO:0005154(epidermal growth factor receptor binding);GO:0009897(external side of plasma membrane);GO:0070062(extracellular exosome);GO:0042113(B cell activation);GO:0006959(humoral immune response);GO:0042100(B cell proliferation);GO:0023026(MHC class II protein complex binding);GO:0023026(MHC class II protein complex binding)","04640(Hematopoietic cell lineage);04640(Hematopoietic cell lineage)","K06466","NA","membrane spanning 4-domains A1 [Source:HGNC Symbol;Acc:HGNC:7315]",{"v":12.2301710273676,"d":"12.23"},{"v":22.732056804686,"d":"22.73"},{"v":0.53801427351908,"d":"0.54"},{"v":-0.894283646897223,"d":"-0.89"},{"v":0.0792486946088101,"d":"0.08"},{"v":0.596871982239328,"d":"0.60"},"down","no"]
["MSTRG.1519","AKR1C3","ENST00000380554;ENST00000603312;ENST00000603484;ENST00000605322;ENST00000439082;ENST00000480697;ENST00000480822","GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0008202(steroid metabolic process);GO:0007186(G-protein coupled receptor signaling pathway);GO:0042572(retinol metabolic process);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0008584(male gonad development);GO:0009267(cellular response to starvation);GO:2000379(positive regulation of reactive oxygen species metabolic process);GO:0008284(positive regulation of cell proliferation);GO:0001523(retinoid metabolic process);GO:0006693(prostaglandin metabolic process);GO:0019371(cyclooxygenase pathway);GO:0051897(positive regulation of protein kinase B signaling);GO:0070293(renal absorption);GO:0004745(retinol dehydrogenase activity);GO:0047035(testosterone dehydrogenase (NAD+) activity);GO:0030216(keratinocyte differentiation);GO:0005622(intracellular);GO:0010942(positive regulation of cell death);GO:0071277(cellular response to calcium ion);GO:0004033(aldo-keto reductase (NADP) activity);GO:0044597(daunorubicin metabolic process);GO:0044598(doxorubicin metabolic process);GO:0001758(retinal dehydrogenase activity);GO:0045550(geranylgeranyl reductase activity);GO:0047718(indanol dehydrogenase activity);GO:0016488(farnesol catabolic process);GO:0016655(oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor);GO:0052650(NADP-retinol dehydrogenase activity);GO:0000060(protein import into nucleus, translocation);GO:0071276(cellular response to cadmium ion);GO:0042448(progesterone metabolic process);GO:0034614(cellular response to reactive oxygen species);GO:2000353(positive regulation of endothelial cell apoptotic process);GO:0004032(alditol:NADP+ 1-oxidoreductase activity);GO:0047023(androsterone dehydrogenase activity);GO:0071395(cellular response to jasmonic acid stimulus);GO:0061370(testosterone biosynthetic process);GO:0047045(testosterone 17-beta-dehydrogenase (NADP+) activity);GO:0018636(phenanthrene 9,10-monooxygenase activity);GO:0035410(dihydrotestosterone 17-beta-dehydrogenase activity);GO:0036130(prostaglandin H2 endoperoxidase reductase activity);GO:0036131(prostaglandin D2 11-ketoreductase activity);GO:0045703(ketoreductase activity);GO:0047017(prostaglandin-F synthase activity);GO:0047020(15-hydroxyprostaglandin-D dehydrogenase (NADP+) activity);GO:0047086(ketosteroid monooxygenase activity);GO:0047115(trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity);GO:0047787(delta4-3-oxosteroid 5beta-reductase activity);GO:0007584(response to nutrient);GO:0042574(retinal metabolic process);GO:0044259(multicellular organismal macromolecule metabolic process);GO:0048385(regulation of retinoic acid receptor signaling pathway);GO:0071379(cellular response to prostaglandin stimulus);GO:0071384(cellular response to corticosteroid stimulus);GO:0071799(cellular response to prostaglandin D stimulus);GO:1900053(negative regulation of retinoic acid biosynthetic process);GO:2000224(regulation of testosterone biosynthetic process);GO:2000224(regulation of testosterone biosynthetic process)","00140(Steroid hormone biosynthesis);00590(Arachidonic acid metabolism);00790(Folate biosynthesis);04913(Ovarian Steroidogenesis);04913(Ovarian Steroidogenesis)","K04119","EC:1.1.1.51;EC:1.1.1.188","aldo-keto reductase family 1 member C3 [Source:HGNC Symbol;Acc:HGNC:386]",{"v":1.29034613768756,"d":"1.29"},{"v":2.41741238724625,"d":"2.42"},{"v":0.533771624773311,"d":"0.53"},{"v":-0.905705480840428,"d":"-0.91"},{"v":0.0792932083099324,"d":"0.08"},{"v":0.596871982239328,"d":"0.60"},"down","no"]
["MSTRG.217","ECE1","ENST00000357071;ENST00000374893;ENST00000415912;ENST00000481130;ENST00000526194;ENST00000527991;ENST00000531334;ENST00000528294;ENST00000264205;ENST00000470394;ENST00000463334;ENST00000473505","GO:0048471(perinuclear region of cytoplasm);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0046872(metal ion binding);GO:0016787(hydrolase activity);GO:0005765(lysosomal membrane);GO:0008270(zinc ion binding);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0008233(peptidase activity);GO:0006508(proteolysis);GO:0004222(metalloendopeptidase activity);GO:0008237(metallopeptidase activity);GO:0016485(protein processing);GO:0070062(extracellular exosome);GO:0042803(protein homodimerization activity);GO:0009897(external side of plasma membrane);GO:0042733(embryonic digit morphogenesis);GO:0007507(heart development);GO:0004175(endopeptidase activity);GO:0031982(vesicle);GO:0019229(regulation of vasoconstriction);GO:0003100(regulation of systemic arterial blood pressure by endothelin);GO:0001921(positive regulation of receptor recycling);GO:0016486(peptide hormone processing);GO:0017046(peptide hormone binding);GO:0042447(hormone catabolic process);GO:0005768(endosome);GO:0010814(substance P catabolic process);GO:0010815(bradykinin catabolic process);GO:0010816(calcitonin catabolic process);GO:0034959(endothelin maturation);GO:0043583(ear development);GO:0031302(intrinsic component of endosome membrane);GO:0033093(Weibel-Palade body);GO:0060037(pharyngeal system development);GO:0060037(pharyngeal system development)","NA","NA","NA","endothelin converting enzyme 1 [Source:HGNC Symbol;Acc:HGNC:3146]",{"v":21.2626914265657,"d":"21.26"},{"v":7.87453933503097,"d":"7.87"},{"v":2.70018226107217,"d":"2.70"},{"v":1.43305679182069,"d":"1.43"},{"v":0.0793597814924142,"d":"0.08"},{"v":0.596871982239328,"d":"0.60"},"up","no"]
["MSTRG.1008","C1orf43","ENST00000350592;ENST00000368521;ENST00000470180;ENST00000368519;ENST00000368518;ENST00000640799;ENST00000483282;ENST00000362076;ENST00000368516;ENST00000493814","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0055114(oxidation-reduction process)","NA","NA","NA","chromosome 1 open reading frame 43 [Source:HGNC Symbol;Acc:HGNC:29876]",{"v":14.4202038903475,"d":"14.42"},{"v":26.8190278285714,"d":"26.82"},{"v":0.537685556035893,"d":"0.54"},{"v":-0.895165378184297,"d":"-0.90"},{"v":0.0793691350322632,"d":"0.08"},{"v":0.596871982239328,"d":"0.60"},"down","no"]
["MSTRG.13104","PHF3","MSTRG.13104.1;ENST00000393387;ENST00000262043;ENST00000515594;ENST00000505138;ENST00000506783;ENST00000509876;ENST00000494284;ENST00000509330","GO:0046872(metal ion binding);GO:0006351(transcription, DNA-templated);GO:0007275(multicellular organism development);GO:0003674(molecular_function);GO:0005575(cellular_component);GO:0005575(cellular_component)","NA","NA","NA","PHD finger protein 3 [Source:HGNC Symbol;Acc:HGNC:8921]",{"v":11.2183553789625,"d":"11.22"},{"v":4.1569976271854,"d":"4.16"},{"v":2.69866773692584,"d":"2.70"},{"v":1.43224736146668,"d":"1.43"},{"v":0.0793794309431933,"d":"0.08"},{"v":0.596871982239328,"d":"0.60"},"up","no"]
["MSTRG.12972","UHRF1BP1","ENST00000192788;ENST00000452449","GO:0005515(protein binding);GO:0042802(identical protein binding);GO:0042826(histone deacetylase binding);GO:0042826(histone deacetylase binding)","NA","NA","NA","UHRF1 binding protein 1 [Source:HGNC Symbol;Acc:HGNC:21216]",{"v":1.45076056237384,"d":"1.45"},{"v":0.533160720024223,"d":"0.53"},{"v":2.7210567243362,"d":"2.72"},{"v":1.44416703195162,"d":"1.44"},{"v":0.07939525030121,"d":"0.08"},{"v":0.596871982239328,"d":"0.60"},"up","no"]
["ENSG00000038532","CLEC16A","ENST00000409790;ENST00000409552;ENST00000261657;ENST00000436973;ENST00000463896;ENST00000494853;ENST00000487189","GO:0016020(membrane);GO:0005794(Golgi apparatus);GO:0005765(lysosomal membrane);GO:0005829(cytosol);GO:0006914(autophagy);GO:0005764(lysosome);GO:0005768(endosome);GO:0003674(molecular_function);GO:0009267(cellular response to starvation);GO:0010008(endosome membrane);GO:0031982(vesicle);GO:0032435(negative regulation of proteasomal ubiquitin-dependent protein catabolic process);GO:1901097(negative regulation of autophagosome maturation);GO:1901098(positive regulation of autophagosome maturation);GO:1901525(negative regulation of macromitophagy);GO:1904263(positive regulation of TORC1 signaling);GO:1904766(negative regulation of macroautophagy by TORC1 signaling);GO:0036020(endolysosome membrane);GO:0036020(endolysosome membrane)","NA","NA","NA","C-type lectin domain containing 16A [Source:HGNC Symbol;Acc:HGNC:29013]",{"v":1.78764144078469,"d":"1.79"},{"v":0.658622205295875,"d":"0.66"},{"v":2.71421374258346,"d":"2.71"},{"v":1.44053433653535,"d":"1.44"},{"v":0.079413147272191,"d":"0.08"},{"v":0.596871982239328,"d":"0.60"},"up","no"]
["ENSG00000162980","ARL5A","ENST00000295087;ENST00000446896;ENST00000428992;ENST00000487723;ENST00000495604;ENST00000487818;ENST00000458140","GO:0005525(GTP binding);GO:0007264(small GTPase mediated signal transduction);GO:0000166(nucleotide binding);GO:0005622(intracellular);GO:0005622(intracellular)","NA","NA","NA","ADP ribosylation factor like GTPase 5A [Source:HGNC Symbol;Acc:HGNC:696]",{"v":2.32406219073853,"d":"2.32"},{"v":4.32991540842764,"d":"4.33"},{"v":0.536745402973701,"d":"0.54"},{"v":-0.897690164901023,"d":"-0.90"},{"v":0.0794595784501852,"d":"0.08"},{"v":0.596871982239328,"d":"0.60"},"down","no"]
["MSTRG.8497","KIDINS220","MSTRG.8497.3;ENST00000569008;ENST00000496725;ENST00000489024;ENST00000459813;ENST00000319688;ENST00000638224;ENST00000474782;ENST00000488729;ENST00000471685;ENST00000471275","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0007399(nervous system development);GO:0005768(endosome);GO:0005829(cytosol);GO:0043234(protein complex);GO:0045859(regulation of protein kinase activity);GO:0005770(late endosome);GO:0030165(PDZ domain binding);GO:0010976(positive regulation of neuron projection development);GO:0000186(activation of MAPKK activity);GO:0038180(nerve growth factor signaling pathway);GO:1990090(cellular response to nerve growth factor stimulus);GO:0019887(protein kinase regulator activity);GO:0001701(in utero embryonic development);GO:0048813(dendrite morphogenesis);GO:0048813(dendrite morphogenesis)","04722(Neurotrophin signaling pathway);04722(Neurotrophin signaling pathway)","NA","NA","kinase D interacting substrate 220 [Source:HGNC Symbol;Acc:HGNC:29508]",{"v":7.49306561296648,"d":"7.49"},{"v":2.77818417514232,"d":"2.78"},{"v":2.697109025388,"d":"2.70"},{"v":1.43141384089405,"d":"1.43"},{"v":0.0795928983237115,"d":"0.08"},{"v":0.597486960719626,"d":"0.60"},"up","no"]
["MSTRG.8657","COX7A2L","ENST00000482463;ENST00000234301;ENST00000463055;ENST00000378669;ENST00000464443;ENST00000468711","GO:0005730(nucleolus);GO:0005739(mitochondrion);GO:1902600(hydrogen ion transmembrane transport);GO:0004129(cytochrome-c oxidase activity);GO:0009055(electron carrier activity);GO:0005746(mitochondrial respiratory chain);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005743(mitochondrial inner membrane);GO:0006123(mitochondrial electron transport, cytochrome c to oxygen);GO:0006123(mitochondrial electron transport, cytochrome c to oxygen)","00190(Oxidative phosphorylation);04260(Cardiac muscle contraction);05010(Alzheimer's disease);05012(Parkinson's disease);05016(Huntington's disease);04932(Non-alcoholic fatty liver disease (NAFLD));04932(Non-alcoholic fatty liver disease (NAFLD))","K02270","NA","cytochrome c oxidase subunit 7A2 like [Source:HGNC Symbol;Acc:HGNC:2289]",{"v":5.32936026137377,"d":"5.33"},{"v":9.89898119464764,"d":"9.90"},{"v":0.538374622254596,"d":"0.54"},{"v":-0.89331768867305,"d":"-0.89"},{"v":0.0797111805273148,"d":"0.08"},{"v":0.597832107655271,"d":"0.60"},"down","no"]
["MSTRG.6327","MED11","ENST00000293777;ENST00000573708;ENST00000575284","GO:0001104(RNA polymerase II transcription cofactor activity);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0016592(mediator complex);GO:0005634(nucleus);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0005515(protein binding);GO:0061630(ubiquitin protein ligase activity);GO:0016567(protein ubiquitination);GO:0000151(ubiquitin ligase complex);GO:0000151(ubiquitin ligase complex)","NA","NA","NA","mediator complex subunit 11 [Source:HGNC Symbol;Acc:HGNC:32687]",{"v":4.94216518551117,"d":"4.94"},{"v":1.80842597901151,"d":"1.81"},{"v":2.73285456129787,"d":"2.73"},{"v":1.45040868368934,"d":"1.45"},{"v":0.079797009855,"d":"0.08"},{"v":0.597832107655271,"d":"0.60"},"up","no"]
["ENSG00000124171","PARD6B","ENST00000371610","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005829(cytosol);GO:0051301(cell division);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0007049(cell cycle);GO:0030054(cell junction);GO:0005923(bicellular tight junction);GO:0007409(axonogenesis);GO:0070062(extracellular exosome);GO:0007043(cell-cell junction assembly);GO:0007163(establishment or maintenance of cell polarity);GO:0030334(regulation of cell migration);GO:0006461(protein complex assembly);GO:0070830(bicellular tight junction assembly);GO:0005634(nucleus);GO:0005938(cell cortex);GO:0016324(apical plasma membrane);GO:0043234(protein complex);GO:0045177(apical part of cell)","04015(Rap1 signaling pathway);04390(Hippo signaling pathway);04144(Endocytosis);04530(Tight junction);04360(Axon guidance);05165(Human papillomavirus infection)","K06093","NA","par-6 family cell polarity regulator beta [Source:HGNC Symbol;Acc:HGNC:16245]",{"v":0.490871555226407,"d":"0.49"},{"v":0.171974664621244,"d":"0.17"},{"v":2.85432482922702,"d":"2.85"},{"v":1.51314952642137,"d":"1.51"},{"v":0.0797983457394628,"d":"0.08"},{"v":0.597832107655271,"d":"0.60"},"up","no"]
["ENSG00000117724","CENPF","ENST00000366955;ENST00000469862;ENST00000464322;ENST00000614578","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0015031(protein transport);GO:0005654(nucleoplasm);GO:0051301(cell division);GO:0005694(chromosome);GO:0042803(protein homodimerization activity);GO:0008134(transcription factor binding);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0007049(cell cycle);GO:0007275(multicellular organism development);GO:0048471(perinuclear region of cytoplasm);GO:0030154(cell differentiation);GO:0000922(spindle pole);GO:0005819(spindle);GO:0030496(midbody);GO:0007059(chromosome segregation);GO:0000775(chromosome, centromeric region);GO:0000776(kinetochore);GO:0000777(condensed chromosome kinetochore);GO:0005829(cytosol);GO:0003682(chromatin binding);GO:0008283(cell proliferation);GO:0070840(dynein complex binding);GO:0007517(muscle organ development);GO:0008022(protein C-terminus binding);GO:0071897(DNA biosynthetic process);GO:0007062(sister chromatid cohesion);GO:0045892(negative regulation of transcription, DNA-templated);GO:0000785(chromatin);GO:0016363(nuclear matrix);GO:0005635(nuclear envelope);GO:0000278(mitotic cell cycle);GO:0051310(metaphase plate congression);GO:0007094(mitotic spindle assembly checkpoint);GO:0000940(condensed chromosome outer kinetochore);GO:0042493(response to drug);GO:0051726(regulation of cell cycle);GO:0016202(regulation of striated muscle tissue development);GO:0001822(kidney development);GO:0010389(regulation of G2/M transition of mitotic cell cycle);GO:0021591(ventricular system development);GO:0051382(kinetochore assembly);GO:0005813(centrosome);GO:0005930(axoneme);GO:0036064(ciliary basal body);GO:0045120(pronucleus);GO:0097539(ciliary transition fiber);GO:0097539(ciliary transition fiber)","NA","NA","NA","centromere protein F [Source:HGNC Symbol;Acc:HGNC:1857]",{"v":0.231202702053037,"d":"0.23"},{"v":0.0825573947818648,"d":"0.08"},{"v":2.80050869657317,"d":"2.80"},{"v":1.48568890837222,"d":"1.49"},{"v":0.0799030679714396,"d":"0.08"},{"v":0.597832107655271,"d":"0.60"},"up","no"]
["ENSG00000246263","UBR5-AS1","ENST00000520820;ENST00000499653","NA","NA","NA","NA","UBR5 antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:51661]",{"v":1.9611645418259,"d":"1.96"},{"v":0.705902240339703,"d":"0.71"},{"v":2.77823816068656,"d":"2.78"},{"v":1.47417027769007,"d":"1.47"},{"v":0.079928931601549,"d":"0.08"},{"v":0.597832107655271,"d":"0.60"},"up","no"]
["MSTRG.7951","MYO9B","MSTRG.7951.3;MSTRG.7951.4;ENST00000599420;ENST00000595641;ENST00000597572;ENST00000598464;ENST00000597881;ENST00000601749;ENST00000598101;ENST00000595618;ENST00000602158;ENST00000596942;ENST00000597073;ENST00000594824;ENST00000593411;ENST00000602177;ENST00000598419;ENST00000601490;ENST00000594971;ENST00000593533;ENST00000397274","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0005829(cytosol);GO:0035556(intracellular signal transduction);GO:0007165(signal transduction);GO:0003774(motor activity);GO:0016459(myosin complex);GO:0003779(actin binding);GO:0005856(cytoskeleton);GO:0005096(GTPase activator activity);GO:0048471(perinuclear region of cytoplasm);GO:0043547(positive regulation of GTPase activity);GO:0005516(calmodulin binding);GO:0005515(protein binding);GO:0051056(regulation of small GTPase mediated signal transduction);GO:0005938(cell cortex);GO:0016887(ATPase activity);GO:0015629(actin cytoskeleton);GO:0005884(actin filament);GO:0007266(Rho protein signal transduction);GO:0017048(Rho GTPase binding);GO:0048495(Roundabout binding);GO:0000146(microfilament motor activity);GO:0030048(actin filament-based movement);GO:0035023(regulation of Rho protein signal transduction);GO:0043531(ADP binding);GO:0035385(Roundabout signaling pathway);GO:0005622(intracellular);GO:0005622(intracellular)","NA","NA","NA","myosin IXB [Source:HGNC Symbol;Acc:HGNC:7609]",{"v":22.5634346115802,"d":"22.56"},{"v":8.37786157720145,"d":"8.38"},{"v":2.69322122401518,"d":"2.69"},{"v":1.42933273919021,"d":"1.43"},{"v":0.0799477536544077,"d":"0.08"},{"v":0.597832107655271,"d":"0.60"},"up","no"]
["ENSG00000163328","GPR155","ENST00000392552;ENST00000392551;ENST00000295500;ENST00000614352","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0055085(transmembrane transport);GO:0035556(intracellular signal transduction);GO:0005737(cytoplasm);GO:0003674(molecular_function);GO:0070062(extracellular exosome);GO:0050890(cognition);GO:0005622(intracellular);GO:0005622(intracellular)","NA","NA","NA","G protein-coupled receptor 155 [Source:HGNC Symbol;Acc:HGNC:22951]",{"v":2.66979499806925,"d":"2.67"},{"v":0.987432080576651,"d":"0.99"},{"v":2.70377583490108,"d":"2.70"},{"v":1.43497554537657,"d":"1.43"},{"v":0.0801220385302944,"d":"0.08"},{"v":0.598275486528292,"d":"0.60"},"up","no"]
["ENSG00000254681","PKD1P5","ENST00000532415;ENST00000538166;ENST00000544578","NA","NA","NA","NA","polycystin 1, transient receptor potential channel interacting pseudogene 5 [Source:HGNC Symbol;Acc:HGNC:30069]",{"v":1.247341,"d":"1.25"},{"v":0.458518213001652,"d":"0.46"},{"v":2.72037394509235,"d":"2.72"},{"v":1.44380497928786,"d":"1.44"},{"v":0.0801574059678893,"d":"0.08"},{"v":0.598275486528292,"d":"0.60"},"up","no"]
["MSTRG.7143","LRRC37A16P","ENST00000586022","NA","NA","NA","NA","leucine rich repeat containing 37 member A16, pseudogene [Source:HGNC Symbol;Acc:HGNC:43820]",{"v":1.32833597640891,"d":"1.33"},{"v":0.483591900393185,"d":"0.48"},{"v":2.74681187862928,"d":"2.75"},{"v":1.45775810769729,"d":"1.46"},{"v":0.0801967652364055,"d":"0.08"},{"v":0.598275486528292,"d":"0.60"},"up","no"]
["ENSG00000263002","ZNF234","ENST00000426739;ENST00000592437;ENST00000590795;ENST00000590748","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0005622(intracellular);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding)","NA","NA","NA","zinc finger protein 234 [Source:HGNC Symbol;Acc:HGNC:13027]",{"v":1.12744164760077,"d":"1.13"},{"v":0.408043975047985,"d":"0.41"},{"v":2.76303956569432,"d":"2.76"},{"v":1.46625622115232,"d":"1.47"},{"v":0.0802131174136357,"d":"0.08"},{"v":0.598275486528292,"d":"0.60"},"up","no"]
["MSTRG.3082","PHB2","ENST00000535923;ENST00000543465;ENST00000537646;ENST00000440277;ENST00000542912;ENST00000536316;ENST00000544134;ENST00000546217;ENST00000546111;ENST00000545555;ENST00000545167;ENST00000399433;ENST00000542294;ENST00000544888","GO:0016020(membrane);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0005739(mitochondrion);GO:0005743(mitochondrial inner membrane);GO:0005515(protein binding);GO:0005741(mitochondrial outer membrane);GO:0070062(extracellular exosome);GO:0050821(protein stabilization);GO:0071944(cell periphery);GO:0030331(estrogen receptor binding);GO:0043234(protein complex);GO:0008022(protein C-terminus binding);GO:0047485(protein N-terminus binding);GO:0043066(negative regulation of apoptotic process);GO:0070374(positive regulation of ERK1 and ERK2 cascade);GO:0009986(cell surface);GO:0043433(negative regulation of sequence-specific DNA binding transcription factor activity);GO:0045892(negative regulation of transcription, DNA-templated);GO:0016363(nuclear matrix);GO:0051091(positive regulation of sequence-specific DNA binding transcription factor activity);GO:0031536(positive regulation of exit from mitosis);GO:0007005(mitochondrion organization);GO:0007062(sister chromatid cohesion);GO:0006851(mitochondrial calcium ion transmembrane transport);GO:0000060(protein import into nucleus, translocation);GO:1902808(positive regulation of cell cycle G1/S phase transition);GO:0033218(amide binding);GO:0009611(response to wounding);GO:0033147(negative regulation of intracellular estrogen receptor signaling pathway);GO:0033600(negative regulation of mammary gland epithelial cell proliferation);GO:0060744(mammary gland branching involved in thelarche);GO:0060749(mammary gland alveolus development);GO:0060762(regulation of branching involved in mammary gland duct morphogenesis);GO:0071300(cellular response to retinoic acid);GO:0071456(cellular response to hypoxia);GO:0030424(axon);GO:0030424(axon)","NA","NA","NA","prohibitin 2 [Source:HGNC Symbol;Acc:HGNC:30306]",{"v":20.6321258355731,"d":"20.63"},{"v":38.2529499114625,"d":"38.25"},{"v":0.539360386148695,"d":"0.54"},{"v":-0.890678529571766,"d":"-0.89"},{"v":0.0803940482487099,"d":"0.08"},{"v":0.59899694023678,"d":"0.60"},"down","no"]
["MSTRG.10354","MTMR3","ENST00000351488;ENST00000401950;ENST00000333027;ENST00000323630;ENST00000445401;ENST00000480776;ENST00000406629;ENST00000495098;ENST00000492087;ENST00000487907;ENST00000491251","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0046872(metal ion binding);GO:0016787(hydrolase activity);GO:0006629(lipid metabolic process);GO:0004725(protein tyrosine phosphatase activity);GO:0016311(dephosphorylation);GO:0035335(peptidyl-tyrosine dephosphorylation);GO:0004721(phosphoprotein phosphatase activity);GO:0005515(protein binding);GO:0005829(cytosol);GO:0019898(extrinsic component of membrane);GO:0006661(phosphatidylinositol biosynthetic process);GO:0004722(protein serine/threonine phosphatase activity);GO:0006470(protein dephosphorylation);GO:0004438(phosphatidylinositol-3-phosphatase activity);GO:0052629(phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity);GO:0016236(macroautophagy);GO:0042149(cellular response to glucose starvation);GO:2000785(regulation of autophagosome assembly);GO:0046856(phosphatidylinositol dephosphorylation);GO:1904562(phosphatidylinositol 5-phosphate metabolic process);GO:1904562(phosphatidylinositol 5-phosphate metabolic process)","00562(Inositol phosphate metabolism);04070(Phosphatidylinositol signaling system);04140(Autophagy - animal);04140(Autophagy - animal)","K18082","EC:3.1.3.48;EC:3.1.3.64","myotubularin related protein 3 [Source:HGNC Symbol;Acc:HGNC:7451]",{"v":10.5895280200949,"d":"10.59"},{"v":3.93252628698374,"d":"3.93"},{"v":2.69280539971091,"d":"2.69"},{"v":1.42910997472774,"d":"1.43"},{"v":0.0804130052380212,"d":"0.08"},{"v":0.59899694023678,"d":"0.60"},"up","no"]
["ENSG00000185619","PCGF3","ENST00000362003;ENST00000440452;ENST00000430644;ENST00000400151;ENST00000427463;ENST00000475288;ENST00000470161;ENST00000488032;ENST00000419774","GO:0046872(metal ion binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0005515(protein binding);GO:0031519(PcG protein complex);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016021(integral component of membrane)","04550(Signaling pathways regulating pluripotency of stem cells);04550(Signaling pathways regulating pluripotency of stem cells)","K11488","NA","polycomb group ring finger 3 [Source:HGNC Symbol;Acc:HGNC:10066]",{"v":2.81314826989899,"d":"2.81"},{"v":1.03938520619529,"d":"1.04"},{"v":2.70655023097416,"d":"2.71"},{"v":1.43645516333608,"d":"1.44"},{"v":0.0804665693071864,"d":"0.08"},{"v":0.599011711130997,"d":"0.60"},"up","no"]
["MSTRG.8783","NFU1","ENST00000410022;ENST00000462320;ENST00000394305;ENST00000419370;ENST00000438184;ENST00000474230;ENST00000303698;ENST00000484177;ENST00000450796;ENST00000471185","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0005739(mitochondrion);GO:0005506(iron ion binding);GO:0005515(protein binding);GO:0051536(iron-sulfur cluster binding);GO:0051539(4 iron, 4 sulfur cluster binding);GO:0016226(iron-sulfur cluster assembly);GO:0016226(iron-sulfur cluster assembly)","NA","NA","NA","NFU1 iron-sulfur cluster scaffold [Source:HGNC Symbol;Acc:HGNC:16287]",{"v":2.75040718616295,"d":"2.75"},{"v":5.14365408511607,"d":"5.14"},{"v":0.534718536793068,"d":"0.53"},{"v":-0.903148404169373,"d":"-0.90"},{"v":0.0806305530702866,"d":"0.08"},{"v":0.599553918989552,"d":"0.60"},"down","no"]
["MSTRG.12159","SERINC5","ENST00000507668;ENST00000512972;ENST00000502747;ENST00000509193;ENST00000513907;ENST00000632581","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0006629(lipid metabolic process);GO:0006665(sphingolipid metabolic process);GO:0005886(plasma membrane);GO:0008654(phospholipid biosynthetic process);GO:0048471(perinuclear region of cytoplasm);GO:0002376(immune system process);GO:0045087(innate immune response);GO:0051607(defense response to virus);GO:0042552(myelination);GO:0006658(phosphatidylserine metabolic process);GO:0070062(extracellular exosome);GO:0015194(L-serine transmembrane transporter activity);GO:0015825(L-serine transport);GO:0016032(viral process);GO:0009597(detection of virus);GO:0006564(L-serine biosynthetic process);GO:0006810(transport);GO:1905361(L-serine transporter activity);GO:1904219(positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity);GO:1904222(positive regulation of serine C-palmitoyltransferase activity);GO:0005794(Golgi apparatus);GO:0043209(myelin sheath);GO:0043209(myelin sheath)","NA","NA","NA","serine incorporator 5 [Source:HGNC Symbol;Acc:HGNC:18825]",{"v":4.62574720626959,"d":"4.63"},{"v":1.71785113782654,"d":"1.72"},{"v":2.69275206938023,"d":"2.69"},{"v":1.42908140223398,"d":"1.43"},{"v":0.0806925225550848,"d":"0.08"},{"v":0.599553918989552,"d":"0.60"},"up","no"]
["MSTRG.4227","TRDV2","ENST00000390469","GO:0002377(immunoglobulin production);GO:0006955(immune response);GO:0005615(extracellular space)","NA","NA","NA","T-cell receptor delta variable 2 [Source:HGNC Symbol;Acc:HGNC:12263]",{"v":14.004496,"d":"14.00"},{"v":26.079298,"d":"26.08"},{"v":0.536996663023675,"d":"0.54"},{"v":-0.897014971768209,"d":"-0.90"},{"v":0.080694288760929,"d":"0.08"},{"v":0.599553918989552,"d":"0.60"},"down","no"]
["ENSG00000107864","CPEB3","ENST00000412050;ENST00000614585;ENST00000265997","GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005886(plasma membrane);GO:0042995(cell projection);GO:0005515(protein binding);GO:0003730(mRNA 3'-UTR binding);GO:0045182(translation regulator activity);GO:0006417(regulation of translation);GO:0030054(cell junction);GO:0045202(synapse);GO:0045211(postsynaptic membrane);GO:0045727(positive regulation of translation);GO:0030425(dendrite);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0071230(cellular response to amino acid stimulus);GO:0061158(3'-UTR-mediated mRNA destabilization);GO:0060213(positive regulation of nuclear-transcribed mRNA poly(A) tail shortening);GO:1900153(positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay);GO:0030014(CCR4-NOT complex);GO:0014069(postsynaptic density);GO:0017148(negative regulation of translation);GO:0000900(translation repressor activity, nucleic acid binding);GO:0043022(ribosome binding);GO:2000766(negative regulation of cytoplasmic translation);GO:1990124(messenger ribonucleoprotein complex);GO:0007616(long-term memory);GO:0043005(neuron projection);GO:0035613(RNA stem-loop binding);GO:0048167(regulation of synaptic plasticity);GO:0060999(positive regulation of dendritic spine development);GO:0097440(apical dendrite);GO:0008135(translation factor activity, RNA binding);GO:0006412(translation);GO:0035925(mRNA 3'-UTR AU-rich region binding);GO:0060998(regulation of dendritic spine development);GO:1900365(positive regulation of mRNA polyadenylation);GO:1900248(negative regulation of cytoplasmic translational elongation);GO:1900248(negative regulation of cytoplasmic translational elongation)","04114(Oocyte meiosis);04914(Progesterone-mediated oocyte maturation);04914(Progesterone-mediated oocyte maturation)","K02602","NA","cytoplasmic polyadenylation element binding protein 3 [Source:HGNC Symbol;Acc:HGNC:21746]",{"v":0.51070707278002,"d":"0.51"},{"v":0.184903667003027,"d":"0.18"},{"v":2.76201700624823,"d":"2.76"},{"v":1.46572220256282,"d":"1.47"},{"v":0.0809413977607985,"d":"0.08"},{"v":0.600828302115022,"d":"0.60"},"up","no"]
["MSTRG.8424","LILRA1","MSTRG.8424.1;ENST00000251372;ENST00000495417;ENST00000473156;ENST00000477255","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0002376(immune system process);GO:0002250(adaptive immune response);GO:0050776(regulation of immune response);GO:0005886(plasma membrane);GO:0007166(cell surface receptor signaling pathway);GO:0004888(transmembrane signaling receptor activity);GO:0006952(defense response);GO:0003823(antigen binding);GO:0003823(antigen binding)","04380(Osteoclast differentiation);04380(Osteoclast differentiation)","K06512","NA","leukocyte immunoglobulin like receptor A1 [Source:HGNC Symbol;Acc:HGNC:6602]",{"v":12.4164896197872,"d":"12.42"},{"v":4.61696485504745,"d":"4.62"},{"v":2.68931863455989,"d":"2.69"},{"v":1.42724069803927,"d":"1.43"},{"v":0.0809692838034969,"d":"0.08"},{"v":0.600828302115022,"d":"0.60"},"up","no"]
["MSTRG.14745","FAM214B","ENST00000378566;MSTRG.14745.6;ENST00000322813;ENST00000605244;ENST00000603301;ENST00000378561;ENST00000378557;ENST00000488109;ENST00000605392;ENST00000605104","GO:0005515(protein binding);GO:0005634(nucleus);GO:0005634(nucleus)","NA","NA","NA","family with sequence similarity 214 member B [Source:HGNC Symbol;Acc:HGNC:25666]",{"v":9.31031148350451,"d":"9.31"},{"v":3.46221373093682,"d":"3.46"},{"v":2.68912095180943,"d":"2.69"},{"v":1.42713464649057,"d":"1.43"},{"v":0.0811526462778363,"d":"0.08"},{"v":0.601804394140813,"d":"0.60"},"up","no"]
["ENSG00000198752","CDC42BPB","ENST00000361246;ENST00000559790;ENST00000558321;ENST00000561271;ENST00000559043;ENST00000560492;ENST00000559245","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0035556(intracellular signal transduction);GO:0005886(plasma membrane);GO:0030036(actin cytoskeleton organization);GO:0000287(magnesium ion binding);GO:0030054(cell junction);GO:0017048(Rho GTPase binding);GO:0016477(cell migration);GO:0031032(actomyosin structure organization);GO:0042641(actomyosin);GO:0031252(cell leading edge);GO:0070062(extracellular exosome);GO:0007165(signal transduction);GO:0005856(cytoskeleton);GO:0005911(cell-cell junction);GO:0007010(cytoskeleton organization);GO:0031532(actin cytoskeleton reorganization);GO:0007163(establishment or maintenance of cell polarity);GO:0005622(intracellular);GO:0005622(intracellular)","NA","NA","NA","CDC42 binding protein kinase beta [Source:HGNC Symbol;Acc:HGNC:1738]",{"v":1.89110353202647,"d":"1.89"},{"v":0.697902686977151,"d":"0.70"},{"v":2.70969515852915,"d":"2.71"},{"v":1.43813055710839,"d":"1.44"},{"v":0.081230600921066,"d":"0.08"},{"v":0.601998065409278,"d":"0.60"},"up","no"]
["MSTRG.15385","ARMCX3","ENST00000471229;ENST00000537169;ENST00000467808;ENST00000479298;ENST00000477980;ENST00000341189;ENST00000491568","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0034613(cellular protein localization);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0031307(integral component of mitochondrial outer membrane);GO:0031307(integral component of mitochondrial outer membrane)","NA","NA","NA","armadillo repeat containing, X-linked 3 [Source:HGNC Symbol;Acc:HGNC:24065]",{"v":1.122883180703,"d":"1.12"},{"v":0.4064085829205,"d":"0.41"},{"v":2.76294160087326,"d":"2.76"},{"v":1.46620506883845,"d":"1.47"},{"v":0.0814288236887985,"d":"0.08"},{"v":0.603082225445164,"d":"0.60"},"up","no"]
["MSTRG.7307","CHMP6","ENST00000325167;ENST00000571457;ENST00000572778","GO:0005622(intracellular);GO:0007034(vacuolar transport);GO:0006810(transport);GO:0016020(membrane);GO:0015031(protein transport);GO:0005515(protein binding);GO:0005768(endosome);GO:0031902(late endosome membrane);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0016197(endosomal transport);GO:0016236(macroautophagy);GO:0019058(viral life cycle);GO:0036258(multivesicular body assembly);GO:0012505(endomembrane system);GO:0010008(endosome membrane);GO:0047485(protein N-terminus binding);GO:0032403(protein complex binding);GO:0007080(mitotic metaphase plate congression);GO:0000920(cell separation after cytokinesis);GO:0006997(nucleus organization);GO:0039702(viral budding via host ESCRT complex);GO:0000815(ESCRT III complex);GO:0007175(negative regulation of epidermal growth factor-activated receptor activity);GO:1904902(ESCRT III complex assembly);GO:1904902(ESCRT III complex assembly)","04144(Endocytosis);04217(Necroptosis);04217(Necroptosis)","K12195","NA","charged multivesicular body protein 6 [Source:HGNC Symbol;Acc:HGNC:25675]",{"v":3.60851774787535,"d":"3.61"},{"v":6.71135478895184,"d":"6.71"},{"v":0.537673519185076,"d":"0.54"},{"v":-0.895197675312544,"d":"-0.90"},{"v":0.0816580263594212,"d":"0.08"},{"v":0.604295723809516,"d":"0.60"},"down","no"]
["MSTRG.9408","RPL37A","ENST00000359681;ENST00000491306;ENST00000456586;ENST00000478153;ENST00000490649;ENST00000487233;ENST00000446558;ENST00000624436;ENST00000420712;ENST00000427280;ENST00000441179;ENST00000598925;ENST00000600880","GO:0003723(RNA binding);GO:0005634(nucleus);GO:0006412(translation);GO:0046872(metal ion binding);GO:0030529(intracellular ribonucleoprotein complex);GO:0005622(intracellular);GO:0003735(structural constituent of ribosome);GO:0005840(ribosome);GO:0005515(protein binding);GO:0005925(focal adhesion);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0006413(translational initiation);GO:0006364(rRNA processing);GO:0000184(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay);GO:0019083(viral transcription);GO:0006614(SRP-dependent cotranslational protein targeting to membrane);GO:0022625(cytosolic large ribosomal subunit);GO:0022625(cytosolic large ribosomal subunit)","03010(Ribosome);03010(Ribosome)","K02921","NA","ribosomal protein L37a [Source:HGNC Symbol;Acc:HGNC:10348]",{"v":19.0164114543195,"d":"19.02"},{"v":35.0817703901476,"d":"35.08"},{"v":0.542059629341286,"d":"0.54"},{"v":-0.883476530719493,"d":"-0.88"},{"v":0.0816967438543822,"d":"0.08"},{"v":0.604295723809516,"d":"0.60"},"down","no"]
["ENSG00000114030","KPNA1","ENST00000344337;ENST00000494339;ENST00000464940;ENST00000465882;ENST00000476916;ENST00000466923;ENST00000493510;ENST00000485027;ENST00000470904","GO:0005634(nucleus);GO:0006810(transport);GO:0005737(cytoplasm);GO:0008565(protein transporter activity);GO:0015031(protein transport);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0005515(protein binding);GO:0030425(dendrite);GO:0006606(protein import into nucleus);GO:0075733(intracellular transport of virus);GO:0043657(host cell);GO:0016032(viral process);GO:0019054(modulation by virus of host process);GO:0006309(apoptotic DNA fragmentation);GO:0006607(NLS-bearing protein import into nucleus);GO:0005643(nuclear pore);GO:0008139(nuclear localization sequence binding);GO:0000018(regulation of DNA recombination);GO:0000018(regulation of DNA recombination)","05164(Influenza A);05164(Influenza A)","K15042","NA","karyopherin subunit alpha 1 [Source:HGNC Symbol;Acc:HGNC:6394]",{"v":2.48742924541474,"d":"2.49"},{"v":4.60092855508224,"d":"4.60"},{"v":0.540636355386805,"d":"0.54"},{"v":-0.887269564937234,"d":"-0.89"},{"v":0.0818234037863427,"d":"0.08"},{"v":0.604424822255773,"d":"0.60"},"down","no"]
["MSTRG.5164","VPS13C","ENST00000249837;ENST00000261517;ENST00000395898;ENST00000559119;ENST00000558338;ENST00000560637;ENST00000395896","GO:0016020(membrane);GO:0005739(mitochondrion);GO:0005741(mitochondrial outer membrane);GO:0070062(extracellular exosome);GO:0005737(cytoplasm);GO:0007005(mitochondrion organization);GO:0005829(cytosol);GO:0006895(Golgi to endosome transport);GO:1905090(negative regulation of parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization);GO:1905090(negative regulation of parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization)","NA","NA","NA","vacuolar protein sorting 13 homolog C [Source:HGNC Symbol;Acc:HGNC:23594]",{"v":6.54503249152275,"d":"6.55"},{"v":2.44226777232519,"d":"2.44"},{"v":2.67989962676839,"d":"2.68"},{"v":1.42217896684899,"d":"1.42"},{"v":0.0818579092157103,"d":"0.08"},{"v":0.604424822255773,"d":"0.60"},"up","no"]
["MSTRG.10237","RGL4","MSTRG.10237.9;ENST00000452208;ENST00000467354;ENST00000423392;ENST00000401461;ENST00000460167;ENST00000615003;ENST00000441897","GO:0005622(intracellular);GO:0007264(small GTPase mediated signal transduction);GO:0043547(positive regulation of GTPase activity);GO:0005085(guanyl-nucleotide exchange factor activity);GO:0031410(cytoplasmic vesicle);GO:0031410(cytoplasmic vesicle)","NA","NA","NA","ral guanine nucleotide dissociation stimulator like 4 [Source:HGNC Symbol;Acc:HGNC:31911]",{"v":1.63250852682927,"d":"1.63"},{"v":3.03023447126193,"d":"3.03"},{"v":0.538740002567992,"d":"0.54"},{"v":-0.892338902619557,"d":"-0.89"},{"v":0.0819294430104531,"d":"0.08"},{"v":0.604424822255773,"d":"0.60"},"down","no"]
["ENSG00000151332","MBIP","ENST00000416007;ENST00000318473;ENST00000604336;ENST00000603139;ENST00000604768;ENST00000603913;ENST00000604154;ENST00000359527;ENST00000621657;ENST00000605579;ENST00000604160","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005730(nucleolus);GO:0005829(cytosol);GO:0005515(protein binding);GO:0042802(identical protein binding);GO:0004860(protein kinase inhibitor activity);GO:0043966(histone H3 acetylation);GO:0005671(Ada2/Gcn5/Ada3 transcription activator complex);GO:0032324(molybdopterin cofactor biosynthetic process);GO:0030366(molybdopterin synthase activity);GO:0000173(inactivation of MAPK activity involved in osmosensory signaling pathway);GO:0000173(inactivation of MAPK activity involved in osmosensory signaling pathway)","NA","NA","NA","MAP3K12 binding inhibitory protein 1 [Source:HGNC Symbol;Acc:HGNC:20427]",{"v":1.11961882554787,"d":"1.12"},{"v":2.10315648125721,"d":"2.10"},{"v":0.53235165120885,"d":"0.53"},{"v":-0.909548544915982,"d":"-0.91"},{"v":0.0819558870218639,"d":"0.08"},{"v":0.604424822255773,"d":"0.60"},"down","no"]
["MSTRG.9561","SIRPA","ENST00000358771;ENST00000400068;ENST00000622179;ENST00000356025","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0050900(leukocyte migration);GO:0005886(plasma membrane);GO:0070062(extracellular exosome);GO:0017124(SH3 domain binding);GO:0043312(neutrophil degranulation);GO:0070821(tertiary granule membrane);GO:0007155(cell adhesion);GO:0101003(ficolin-1-rich granule membrane);GO:0101003(ficolin-1-rich granule membrane)","04380(Osteoclast differentiation);04380(Osteoclast differentiation)","K06551","NA","signal regulatory protein alpha [Source:HGNC Symbol;Acc:HGNC:9662]",{"v":24.7501013616811,"d":"24.75"},{"v":9.24338599368587,"d":"9.24"},{"v":2.67760119274342,"d":"2.68"},{"v":1.42094109878894,"d":"1.42"},{"v":0.0820844504197377,"d":"0.08"},{"v":0.604424822255773,"d":"0.60"},"up","no"]
["MSTRG.13161","UBE2J1","MSTRG.13161.2;ENST00000435041","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0016740(transferase activity);GO:0016567(protein ubiquitination);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005737(cytoplasm);GO:0018279(protein N-linked glycosylation via asparagine);GO:0061630(ubiquitin protein ligase activity);GO:0061631(ubiquitin conjugating enzyme activity);GO:0030433(ubiquitin-dependent ERAD pathway);GO:0031625(ubiquitin protein ligase binding);GO:1904153(negative regulation of retrograde protein transport, ER to cytosol);GO:0007286(spermatid development);GO:0042534(regulation of tumor necrosis factor biosynthetic process)","04141(Protein processing in endoplasmic reticulum);04120(Ubiquitin mediated proteolysis);05012(Parkinson's disease)","K10578","EC:2.3.2.23","ubiquitin conjugating enzyme E2 J1 [Source:HGNC Symbol;Acc:HGNC:17598]",{"v":14.6265046344988,"d":"14.63"},{"v":26.9621508027972,"d":"26.96"},{"v":0.542482858340121,"d":"0.54"},{"v":-0.882350543649905,"d":"-0.88"},{"v":0.0821102381875979,"d":"0.08"},{"v":0.604424822255773,"d":"0.60"},"down","no"]
["MSTRG.9190","CD302;LY75;LY75-CD302","ENST00000553424;ENST00000263636;ENST00000504764;ENST00000259053;ENST00000505052;ENST00000471164;ENST00000492955;ENST00000480212;ENST00000484559;ENST00000429078","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0030246(carbohydrate binding);GO:0042995(cell projection);GO:0007165(signal transduction);GO:0004888(transmembrane signaling receptor activity);GO:0005887(integral component of plasma membrane);GO:0030175(filopodium);GO:0005938(cell cortex);GO:0005902(microvillus);GO:0006909(phagocytosis);GO:0006897(endocytosis);GO:0070062(extracellular exosome);GO:0006954(inflammatory response);GO:0006955(immune response);GO:0004872(receptor activity);GO:0006909(phagocytosis)","NA","NA","NA","CD302 molecule [Source:HGNC Symbol;Acc:HGNC:30843];lymphocyte antigen 75 [Source:HGNC Symbol;Acc:HGNC:6729];LY75-CD302 readthrough [Source:HGNC Symbol;Acc:HGNC:38828]",{"v":8.74222233146897,"d":"8.74"},{"v":3.26258573642508,"d":"3.26"},{"v":2.6795379609083,"d":"2.68"},{"v":1.42198425479756,"d":"1.42"},{"v":0.0821709638596131,"d":"0.08"},{"v":0.604424822255773,"d":"0.60"},"up","no"]
["ENSG00000170074","FAM153A","ENST00000360669;ENST00000513554;ENST00000503136;ENST00000515787;ENST00000509607;ENST00000505531;ENST00000512544;ENST00000614127;ENST00000393518;ENST00000503567;ENST00000510276;ENST00000506011","NA","NA","NA","NA","family with sequence similarity 153 member A [Source:HGNC Symbol;Acc:HGNC:29940]",{"v":0.284533015478424,"d":"0.28"},{"v":0.101190827978424,"d":"0.10"},{"v":2.81184590701336,"d":"2.81"},{"v":1.4915175349229,"d":"1.49"},{"v":0.0822304165042345,"d":"0.08"},{"v":0.604424822255773,"d":"0.60"},"up","no"]
["MSTRG.9398","PIKFYVE","ENST00000264380;ENST00000477200;ENST00000443896;ENST00000392202;ENST00000407449;ENST00000308862;ENST00000422495;ENST00000452564","GO:0016020(membrane);GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0035556(intracellular signal transduction);GO:0005515(protein binding);GO:0036092(phosphatidylinositol-3-phosphate biosynthetic process);GO:0016307(phosphatidylinositol phosphate kinase activity);GO:0046488(phosphatidylinositol metabolic process);GO:0046854(phosphatidylinositol phosphorylation);GO:0005768(endosome);GO:0010008(endosome membrane);GO:0042147(retrograde transport, endosome to Golgi);GO:0031901(early endosome membrane);GO:0006661(phosphatidylinositol biosynthetic process);GO:0000139(Golgi membrane);GO:0034504(protein localization to nucleus);GO:0043813(phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity);GO:0045121(membrane raft);GO:2000785(regulation of autophagosome assembly);GO:0031902(late endosome membrane);GO:1904562(phosphatidylinositol 5-phosphate metabolic process);GO:0000285(1-phosphatidylinositol-3-phosphate 5-kinase activity);GO:0016308(1-phosphatidylinositol-4-phosphate 5-kinase activity);GO:0008270(zinc ion binding);GO:0032288(myelin assembly);GO:0005829(cytosol);GO:0005911(cell-cell junction);GO:0012506(vesicle membrane);GO:0031410(cytoplasmic vesicle);GO:0048471(perinuclear region of cytoplasm);GO:0005622(intracellular);GO:0005622(intracellular)","00562(Inositol phosphate metabolism);04070(Phosphatidylinositol signaling system);04145(Phagosome);04810(Regulation of actin cytoskeleton);04810(Regulation of actin cytoskeleton)","K00921","EC:2.7.1.150","phosphoinositide kinase, FYVE-type zinc finger containing [Source:HGNC Symbol;Acc:HGNC:23785]",{"v":6.39787417817578,"d":"6.40"},{"v":2.38928866515879,"d":"2.39"},{"v":2.67773177493,"d":"2.68"},{"v":1.42101145492709,"d":"1.42"},{"v":0.0822385737756285,"d":"0.08"},{"v":0.604424822255773,"d":"0.60"},"up","no"]
["ENSG00000162408","NOL9","ENST00000377705;ENST00000460777;ENST00000464383;ENST00000462798","GO:0003723(RNA binding);GO:0005634(nucleus);GO:0016020(membrane);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0005730(nucleolus);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0045111(intermediate filament cytoskeleton);GO:0005515(protein binding);GO:0006364(rRNA processing);GO:0005654(nucleoplasm);GO:0000460(maturation of 5.8S rRNA);GO:0051731(polynucleotide 5'-hydroxyl-kinase activity);GO:0000448(cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA));GO:0000448(cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA))","NA","NA","NA","nucleolar protein 9 [Source:HGNC Symbol;Acc:HGNC:26265]",{"v":2.28544377142465,"d":"2.29"},{"v":0.845235814068285,"d":"0.85"},{"v":2.70391260448887,"d":"2.70"},{"v":1.43504852177242,"d":"1.44"},{"v":0.0822543153359348,"d":"0.08"},{"v":0.604424822255773,"d":"0.60"},"up","no"]
["ENSG00000137133","HINT2","ENST00000259667;ENST00000490578;ENST00000474848;ENST00000472085;ENST00000474908;ENST00000471774;ENST00000461169","GO:0000166(nucleotide binding);GO:0005730(nucleolus);GO:0016787(hydrolase activity);GO:0005739(mitochondrion);GO:0003824(catalytic activity);GO:0006629(lipid metabolic process);GO:0006694(steroid biosynthetic process);GO:0006915(apoptotic process);GO:0044240(multicellular organismal lipid catabolic process);GO:2000757(negative regulation of peptidyl-lysine acetylation);GO:2000757(negative regulation of peptidyl-lysine acetylation)","NA","NA","NA","histidine triad nucleotide binding protein 2 [Source:HGNC Symbol;Acc:HGNC:18344]",{"v":1.05598892442589,"d":"1.06"},{"v":1.98687706638831,"d":"1.99"},{"v":0.531481762153225,"d":"0.53"},{"v":-0.911907908497937,"d":"-0.91"},{"v":0.0822867169539635,"d":"0.08"},{"v":0.604424822255773,"d":"0.60"},"down","no"]
["MSTRG.5998","CMTM2","ENST00000532362;ENST00000268595;ENST00000379486","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005125(cytokine activity);GO:0005615(extracellular space);GO:0006935(chemotaxis);GO:0006935(chemotaxis)","NA","NA","NA","CKLF like MARVEL transmembrane domain containing 2 [Source:HGNC Symbol;Acc:HGNC:19173]",{"v":18.4705052293658,"d":"18.47"},{"v":34.0650414708949,"d":"34.07"},{"v":0.54221290894793,"d":"0.54"},{"v":-0.883068633771006,"d":"-0.88"},{"v":0.082640757276888,"d":"0.08"},{"v":0.606641665143174,"d":"0.61"},"down","no"]
["MSTRG.6027","RIPOR1","ENST00000569733;ENST00000042381;ENST00000561534;ENST00000565176;ENST00000428437;ENST00000566559;ENST00000564616;ENST00000562116;ENST00000566730;ENST00000569179;ENST00000569474;ENST00000566920;ENST00000565190;ENST00000566907;ENST00000566522;ENST00000379312;ENST00000566815;ENST00000565679","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005794(Golgi apparatus);GO:0005515(protein binding);GO:0003674(molecular_function);GO:0008150(biological_process);GO:0070062(extracellular exosome);GO:0009267(cellular response to starvation);GO:0030335(positive regulation of cell migration);GO:0051683(establishment of Golgi localization);GO:0007266(Rho protein signal transduction);GO:0090316(positive regulation of intracellular protein transport);GO:0071889(14-3-3 protein binding);GO:0009611(response to wounding);GO:0034067(protein localization to Golgi apparatus);GO:0012506(vesicle membrane);GO:0012506(vesicle membrane)","NA","NA","NA","RHO family interacting cell polarization regulator 1 [Source:HGNC Symbol;Acc:HGNC:25836]",{"v":6.14904409228712,"d":"6.15"},{"v":2.29084254554912,"d":"2.29"},{"v":2.68418451727907,"d":"2.68"},{"v":1.42448384926298,"d":"1.42"},{"v":0.0829413293488272,"d":"0.08"},{"v":0.607471827824354,"d":"0.61"},"up","no"]
["MSTRG.8077","COX6B1","ENST00000246554;ENST00000392201;ENST00000590618;ENST00000592141","GO:0005739(mitochondrion);GO:1902600(hydrogen ion transmembrane transport);GO:0005758(mitochondrial intermembrane space);GO:0021762(substantia nigra development);GO:0004129(cytochrome-c oxidase activity);GO:0006123(mitochondrial electron transport, cytochrome c to oxygen);GO:0005743(mitochondrial inner membrane);GO:0005743(mitochondrial inner membrane)","00190(Oxidative phosphorylation);04260(Cardiac muscle contraction);05010(Alzheimer's disease);05012(Parkinson's disease);05016(Huntington's disease);04932(Non-alcoholic fatty liver disease (NAFLD));04932(Non-alcoholic fatty liver disease (NAFLD))","K02267","NA","cytochrome c oxidase subunit 6B1 [Source:HGNC Symbol;Acc:HGNC:2280]",{"v":40.6527008311966,"d":"40.65"},{"v":74.7976667179487,"d":"74.80"},{"v":0.543502259027573,"d":"0.54"},{"v":-0.879642063165407,"d":"-0.88"},{"v":0.0829548296129886,"d":"0.08"},{"v":0.607471827824354,"d":"0.61"},"down","no"]
["MSTRG.296","WASF2","ENST00000618852;ENST00000536657","GO:0005737(cytoplasm);GO:0003779(actin binding);GO:0030036(actin cytoskeleton organization);GO:0005856(cytoskeleton);GO:0042995(cell projection);GO:0005515(protein binding);GO:0038096(Fc-gamma receptor signaling pathway involved in phagocytosis);GO:0005829(cytosol);GO:0045296(cadherin binding);GO:0030027(lamellipodium);GO:0070062(extracellular exosome);GO:0016032(viral process);GO:0017124(SH3 domain binding);GO:0015629(actin cytoskeleton);GO:0048010(vascular endothelial growth factor receptor signaling pathway);GO:0032403(protein complex binding);GO:0010592(positive regulation of lamellipodium assembly);GO:0007188(adenylate cyclase-modulating G-protein coupled receptor signaling pathway);GO:0051497(negative regulation of stress fiber assembly);GO:0031209(SCAR complex);GO:0005622(intracellular);GO:0001525(angiogenesis);GO:0001667(ameboidal-type cell migration);GO:0006897(endocytosis);GO:0016601(Rac protein signal transduction);GO:0030032(lamellipodium assembly);GO:0030048(actin filament-based movement);GO:0035855(megakaryocyte development);GO:0072673(lamellipodium morphogenesis);GO:0001726(ruffle);GO:0005769(early endosome);GO:0005911(cell-cell junction);GO:0005911(cell-cell junction)","04520(Adherens junction);04810(Regulation of actin cytoskeleton);04666(Fc gamma R-mediated phagocytosis);05231(Choline metabolism in cancer);05132(Salmonella infection);05131(Shigellosis);05100(Bacterial invasion of epithelial cells);05100(Bacterial invasion of epithelial cells)","K05748","NA","WAS protein family member 2 [Source:HGNC Symbol;Acc:HGNC:12733]",{"v":12.689361,"d":"12.69"},{"v":4.74468441173362,"d":"4.74"},{"v":2.67443730685631,"d":"2.67"},{"v":1.41923538497118,"d":"1.42"},{"v":0.0829719061457866,"d":"0.08"},{"v":0.607471827824354,"d":"0.61"},"up","no"]
["MSTRG.15420","RPL39","ENST00000468844;ENST00000361575;ENST00000477403","GO:0003723(RNA binding);GO:0006412(translation);GO:0030529(intracellular ribonucleoprotein complex);GO:0005622(intracellular);GO:0003735(structural constituent of ribosome);GO:0005840(ribosome);GO:0005615(extracellular space);GO:0005829(cytosol);GO:0002227(innate immune response in mucosa);GO:0019731(antibacterial humoral response);GO:0050830(defense response to Gram-positive bacterium);GO:0061844(antimicrobial humoral immune response mediated by antimicrobial peptide);GO:0006413(translational initiation);GO:0006364(rRNA processing);GO:0000184(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay);GO:0019083(viral transcription);GO:0006614(SRP-dependent cotranslational protein targeting to membrane);GO:0022625(cytosolic large ribosomal subunit);GO:0022625(cytosolic large ribosomal subunit)","03010(Ribosome);03010(Ribosome)","K02924","NA","ribosomal protein L39 [Source:HGNC Symbol;Acc:HGNC:10350]",{"v":35.635829714154,"d":"35.64"},{"v":65.5223019626556,"d":"65.52"},{"v":0.543873286601936,"d":"0.54"},{"v":-0.878657528126905,"d":"-0.88"},{"v":0.0829877724437556,"d":"0.08"},{"v":0.607471827824354,"d":"0.61"},"down","no"]
["MSTRG.10904","TMA7","ENST00000477624;ENST00000438607;ENST00000479126","NA","NA","NA","NA","translation machinery associated 7 homolog [Source:HGNC Symbol;Acc:HGNC:26932]",{"v":27.3740097647059,"d":"27.37"},{"v":50.3633971264267,"d":"50.36"},{"v":0.543529851570362,"d":"0.54"},{"v":-0.879568822229342,"d":"-0.88"},{"v":0.0830226251233834,"d":"0.08"},{"v":0.607471827824354,"d":"0.61"},"down","no"]
["MSTRG.14365","RPS20","ENST00000524349;ENST00000521262;ENST00000009589;ENST00000519606;ENST00000518875;ENST00000520627;ENST00000519807;ENST00000521289;ENST00000523936;ENST00000520490;ENST00000519369","GO:0003723(RNA binding);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0006412(translation);GO:0030529(intracellular ribonucleoprotein complex);GO:0005622(intracellular);GO:0003735(structural constituent of ribosome);GO:0005840(ribosome);GO:0015935(small ribosomal subunit);GO:0005515(protein binding);GO:0022627(cytosolic small ribosomal subunit);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0031012(extracellular matrix);GO:0002181(cytoplasmic translation);GO:0006413(translational initiation);GO:0006364(rRNA processing);GO:0000184(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay);GO:0019083(viral transcription);GO:0006614(SRP-dependent cotranslational protein targeting to membrane);GO:0006614(SRP-dependent cotranslational protein targeting to membrane)","03010(Ribosome);03010(Ribosome)","K02969","NA","ribosomal protein S20 [Source:HGNC Symbol;Acc:HGNC:10405]",{"v":86.1509130146569,"d":"86.15"},{"v":158.29758171952,"d":"158.30"},{"v":0.544233917403133,"d":"0.54"},{"v":-0.877701224767065,"d":"-0.88"},{"v":0.0830677053806143,"d":"0.08"},{"v":0.607471827824354,"d":"0.61"},"down","no"]
["MSTRG.10225","AC245452.1","ENST00000458178","NA","NA","NA","NA",null,{"v":0.105389,"d":"0.11"},{"v":0.038392,"d":"0.04"},{"v":2.74507709939571,"d":"2.75"},{"v":1.45684666994224,"d":"1.46"},{"v":0.0832502685283217,"d":"0.08"},{"v":0.607972153145183,"d":"0.61"},"up","no"]
["MSTRG.2577","PACS1","ENST00000320580;ENST00000529757;ENST00000531597;ENST00000529677;ENST00000529795;ENST00000524784;ENST00000525798;ENST00000531298;ENST00000527380;ENST00000533811;ENST00000533756;ENST00000527224;ENST00000528935;ENST00000534273","GO:0005794(Golgi apparatus);GO:0005515(protein binding);GO:0000042(protein targeting to Golgi);GO:0030137(COPI-coated vesicle);GO:0005829(cytosol);GO:0016032(viral process);GO:0044325(ion channel binding);GO:0050690(regulation of defense response to virus by virus);GO:0072661(protein targeting to plasma membrane);GO:0072661(protein targeting to plasma membrane)","NA","NA","NA","phosphofurin acidic cluster sorting protein 1 [Source:HGNC Symbol;Acc:HGNC:30032]",{"v":13.9056773238907,"d":"13.91"},{"v":5.20732338331305,"d":"5.21"},{"v":2.67040786605488,"d":"2.67"},{"v":1.41706010947674,"d":"1.42"},{"v":0.0832599287439653,"d":"0.08"},{"v":0.607972153145183,"d":"0.61"},"up","no"]
["MSTRG.10537","SMDT1","ENST00000331479;ENST00000484235;ENST00000422252","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005634(nucleus);GO:0005739(mitochondrion);GO:0005743(mitochondrial inner membrane);GO:0006811(ion transport);GO:0031305(integral component of mitochondrial inner membrane);GO:0006816(calcium ion transport);GO:0005515(protein binding);GO:0005759(mitochondrial matrix);GO:0006851(mitochondrial calcium ion transmembrane transport);GO:0051560(mitochondrial calcium ion homeostasis);GO:0036444(mitochondrial calcium uptake);GO:1990246(uniplex complex);GO:1990246(uniplex complex)","NA","NA","NA","single-pass membrane protein with aspartate rich tail 1 [Source:HGNC Symbol;Acc:HGNC:25055]",{"v":10.5015326863085,"d":"10.50"},{"v":19.3466950595032,"d":"19.35"},{"v":0.542807577935648,"d":"0.54"},{"v":-0.881487233058624,"d":"-0.88"},{"v":0.083314353053955,"d":"0.08"},{"v":0.607972153145183,"d":"0.61"},"down","no"]
["MSTRG.2370","SLC39A13","ENST00000354884;ENST00000531865;ENST00000524886;ENST00000528979;ENST00000362021;ENST00000524928;ENST00000533076;ENST00000531419;ENST00000529740;ENST00000531974;ENST00000527829","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0055085(transmembrane transport);GO:0046873(metal ion transmembrane transporter activity);GO:0030001(metal ion transport);GO:0048471(perinuclear region of cytoplasm);GO:0006810(transport);GO:0005794(Golgi apparatus);GO:0006811(ion transport);GO:0005515(protein binding);GO:0000139(Golgi membrane);GO:0042803(protein homodimerization activity);GO:0006829(zinc II ion transport);GO:0030173(integral component of Golgi membrane);GO:0005385(zinc ion transmembrane transporter activity);GO:0006882(cellular zinc ion homeostasis);GO:0071577(zinc II ion transmembrane transport);GO:0010043(response to zinc ion);GO:0061448(connective tissue development);GO:0005783(endoplasmic reticulum);GO:0005783(endoplasmic reticulum)","NA","NA","NA","solute carrier family 39 member 13 [Source:HGNC Symbol;Acc:HGNC:20859]",{"v":1.33423210732984,"d":"1.33"},{"v":2.48581778075916,"d":"2.49"},{"v":0.536737695601473,"d":"0.54"},{"v":-0.897710881366342,"d":"-0.90"},{"v":0.0834434450546943,"d":"0.08"},{"v":0.607972153145183,"d":"0.61"},"down","no"]
["ENSG00000146776","ATXN7L1","ENST00000419735;ENST00000478915;ENST00000318724;ENST00000485652;ENST00000472910;ENST00000464874;ENST00000472195;ENST00000474433;ENST00000481880;ENST00000477775;ENST00000484475","GO:0005515(protein binding);GO:0005515(protein binding)","NA","NA","NA","ataxin 7 like 1 [Source:HGNC Symbol;Acc:HGNC:22210]",{"v":1.40501792597951,"d":"1.41"},{"v":0.519015355877034,"d":"0.52"},{"v":2.70708353822269,"d":"2.71"},{"v":1.43673940854291,"d":"1.44"},{"v":0.08345039653433,"d":"0.08"},{"v":0.607972153145183,"d":"0.61"},"up","no"]
["MSTRG.1134","DEDD","ENST00000368006;ENST00000458050;ENST00000368005;ENST00000490843;ENST00000473679;ENST00000486041;ENST00000489249;ENST00000545495;ENST00000472996;ENST00000496632;ENST00000463227;ENST00000464113","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0042981(regulation of apoptotic process);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0006915(apoptotic process);GO:0005730(nucleolus);GO:0008625(extrinsic apoptotic signaling pathway via death domain receptors);GO:0007283(spermatogenesis);GO:0042177(negative regulation of protein catabolic process);GO:0046697(decidualization);GO:1901837(negative regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter);GO:1901837(negative regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter)","NA","NA","NA","death effector domain containing [Source:HGNC Symbol;Acc:HGNC:2755]",{"v":5.09163118114144,"d":"5.09"},{"v":9.38170849273307,"d":"9.38"},{"v":0.542718971185828,"d":"0.54"},{"v":-0.881722754739677,"d":"-0.88"},{"v":0.0835058345245375,"d":"0.08"},{"v":0.607972153145183,"d":"0.61"},"down","no"]
["MSTRG.2520","SF1","MSTRG.2520.1;ENST00000433274;ENST00000227503;ENST00000486960;ENST00000377390;ENST00000482693;ENST00000448404;ENST00000377394;ENST00000334944;ENST00000496969;ENST00000486867;MSTRG.2520.2;ENST00000413951;ENST00000633899;ENST00000443908;ENST00000432725;ENST00000413725;ENST00000463343;ENST00000377387;ENST00000477596;ENST00000626028;ENST00000472725;ENST00000489544","GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0006397(mRNA processing);GO:0008380(RNA splicing);GO:0005634(nucleus);GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0005654(nucleoplasm);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0005840(ribosome);GO:0005515(protein binding);GO:0005681(spliceosomal complex);GO:0045131(pre-mRNA branch point binding);GO:0000398(mRNA splicing, via spliceosome);GO:1903507(negative regulation of nucleic acid-templated transcription);GO:0042802(identical protein binding);GO:0003714(transcription corepressor activity);GO:0000245(spliceosomal complex assembly);GO:0000389(mRNA 3'-splice site recognition);GO:0030238(male sex determination);GO:0030575(nuclear body organization);GO:0033327(Leydig cell differentiation);GO:0048662(negative regulation of smooth muscle cell proliferation);GO:0050810(regulation of steroid biosynthetic process);GO:0016604(nuclear body);GO:0016604(nuclear body)","NA","NA","NA","splicing factor 1 [Source:HGNC Symbol;Acc:HGNC:12950]",{"v":22.3073331658048,"d":"22.31"},{"v":8.35542228684551,"d":"8.36"},{"v":2.66980320084177,"d":"2.67"},{"v":1.41673340047698,"d":"1.42"},{"v":0.0835491186200671,"d":"0.08"},{"v":0.607972153145183,"d":"0.61"},"up","no"]
["MSTRG.1941","CUEDC2","ENST00000369937;ENST00000486762;ENST00000465409;ENST00000477994","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0031965(nuclear membrane);GO:0005515(protein binding);GO:0010936(negative regulation of macrophage cytokine production);GO:1900016(negative regulation of cytokine production involved in inflammatory response);GO:1900016(negative regulation of cytokine production involved in inflammatory response)","NA","NA","NA","CUE domain containing 2 [Source:HGNC Symbol;Acc:HGNC:28352]",{"v":8.46778301770538,"d":"8.47"},{"v":15.609595934136,"d":"15.61"},{"v":0.542472915598509,"d":"0.54"},{"v":-0.882376985914855,"d":"-0.88"},{"v":0.0835745124841521,"d":"0.08"},{"v":0.607972153145183,"d":"0.61"},"down","no"]
["ENSG00000128881","TTBK2","ENST00000267890;ENST00000567485;ENST00000567840;ENST00000564431;ENST00000562880;ENST00000566931","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0005829(cytosol);GO:0005856(cytoskeleton);GO:0042995(cell projection);GO:0005515(protein binding);GO:0005615(extracellular space);GO:0007224(smoothened signaling pathway);GO:0060271(cilium assembly);GO:0005929(cilium);GO:0030030(cell projection organization);GO:0005814(centriole);GO:0036064(ciliary basal body);GO:0035869(ciliary transition zone);GO:0008360(regulation of cell shape);GO:0097711(ciliary basal body docking);GO:0018105(peptidyl-serine phosphorylation);GO:0005198(structural molecule activity);GO:0045111(intermediate filament cytoskeleton);GO:0005882(intermediate filament);GO:0045095(keratin filament);GO:0045095(keratin filament)","NA","NA","NA","tau tubulin kinase 2 [Source:HGNC Symbol;Acc:HGNC:19141]",{"v":1.73631606541767,"d":"1.74"},{"v":0.64695157118526,"d":"0.65"},{"v":2.68384241224829,"d":"2.68"},{"v":1.42429996299023,"d":"1.42"},{"v":0.0836072960107515,"d":"0.08"},{"v":0.607972153145183,"d":"0.61"},"up","no"]
["MSTRG.8084","TYROBP","ENST00000544690;ENST00000588439;ENST00000587837;ENST00000589517;ENST00000585901;ENST00000262629;ENST00000586946;ENST00000424586;MSTRG.8084.2;MSTRG.8084.3;MSTRG.8084.4;ENST00000585626;MSTRG.8084.7;MSTRG.8084.1","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005515(protein binding);GO:0050776(regulation of immune response);GO:0005886(plasma membrane);GO:0042802(identical protein binding);GO:0045087(innate immune response);GO:0005887(integral component of plasma membrane);GO:0005102(receptor binding);GO:0043312(neutrophil degranulation);GO:0007165(signal transduction);GO:0009986(cell surface);GO:0030667(secretory granule membrane);GO:0035556(intracellular signal transduction);GO:0005057(signal transducer activity, downstream of receptor);GO:0006968(cellular defense response);GO:0002281(macrophage activation involved in immune response);GO:0002283(neutrophil activation involved in immune response);GO:0007229(integrin-mediated signaling pathway);GO:2001204(regulation of osteoclast development);GO:2001204(regulation of osteoclast development)","04650(Natural killer cell mediated cytotoxicity);04380(Osteoclast differentiation);04380(Osteoclast differentiation)","K07992","NA","TYRO protein tyrosine kinase binding protein [Source:HGNC Symbol;Acc:HGNC:12449]",{"v":71.1247412914521,"d":"71.12"},{"v":130.433814857878,"d":"130.43"},{"v":0.545293728999266,"d":"0.55"},{"v":-0.874894530652775,"d":"-0.87"},{"v":0.0839442494382557,"d":"0.08"},{"v":0.609918368937209,"d":"0.61"},"down","no"]
["MSTRG.13512","AC005062.1;MACC1","ENST00000449573;ENST00000400331","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0006366(transcription from RNA polymerase II promoter);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0005739(mitochondrion);GO:0008083(growth factor activity);GO:0001228(transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0000977(RNA polymerase II regulatory region sequence-specific DNA binding);GO:0051781(positive regulation of cell division)","NA","NA","NA","MACC1, MET transcriptional regulator [Source:HGNC Symbol;Acc:HGNC:30215]",{"v":9.05358305160243,"d":"9.05"},{"v":16.5995312933063,"d":"16.60"},{"v":0.545411969267666,"d":"0.55"},{"v":-0.874581733809788,"d":"-0.87"},{"v":0.0839799769164382,"d":"0.08"},{"v":0.609918368937209,"d":"0.61"},"down","no"]
["MSTRG.11791","SEC24B","ENST00000399100;ENST00000265175;ENST00000504968","GO:0006810(transport);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0006886(intracellular protein transport);GO:0015031(protein transport);GO:0008270(zinc ion binding);GO:0005794(Golgi apparatus);GO:0006888(ER to Golgi vesicle-mediated transport);GO:0030127(COPII vesicle coat);GO:0005829(cytosol);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0000139(Golgi membrane);GO:0048471(perinuclear region of cytoplasm);GO:0016192(vesicle-mediated transport);GO:0005515(protein binding);GO:0019886(antigen processing and presentation of exogenous peptide antigen via MHC class II);GO:0048208(COPII vesicle coating);GO:0012507(ER to Golgi transport vesicle membrane);GO:0002474(antigen processing and presentation of peptide antigen via MHC class I);GO:0090110(cargo loading into COPII-coated vesicle);GO:0001843(neural tube closure);GO:0002093(auditory receptor cell morphogenesis);GO:0003151(outflow tract morphogenesis);GO:0021747(cochlear nucleus development);GO:0035909(aorta morphogenesis);GO:0060088(auditory receptor cell stereocilium organization);GO:0060425(lung morphogenesis);GO:0060463(lung lobe morphogenesis);GO:0060982(coronary artery morphogenesis);GO:0061156(pulmonary artery morphogenesis);GO:0072358(cardiovascular system development);GO:0090178(regulation of establishment of planar polarity involved in neural tube closure);GO:1901301(regulation of cargo loading into COPII-coated vesicle);GO:0030134(ER to Golgi transport vesicle);GO:0030134(ER to Golgi transport vesicle)","04141(Protein processing in endoplasmic reticulum);04141(Protein processing in endoplasmic reticulum)","K14007","NA","SEC24 homolog B, COPII coat complex component [Source:HGNC Symbol;Acc:HGNC:10704]",{"v":8.91952756869132,"d":"8.92"},{"v":3.34504148112665,"d":"3.35"},{"v":2.66649236459905,"d":"2.67"},{"v":1.41494319692364,"d":"1.41"},{"v":0.0842720389169201,"d":"0.08"},{"v":0.611451541537936,"d":"0.61"},"up","no"]
["MSTRG.3065","ZNF384","ENST00000319770;ENST00000361959;ENST00000537248;ENST00000544482;ENST00000535485;ENST00000542519;ENST00000542351;ENST00000417772;ENST00000355772;ENST00000436774;ENST00000542605;ENST00000537383;ENST00000396801;ENST00000540915","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0003677(DNA binding)","NA","NA","NA","zinc finger protein 384 [Source:HGNC Symbol;Acc:HGNC:11955]",{"v":4.10861790387956,"d":"4.11"},{"v":1.52974593746381,"d":"1.53"},{"v":2.6858171695434,"d":"2.69"},{"v":1.42536110015978,"d":"1.43"},{"v":0.084320960945012,"d":"0.08"},{"v":0.611451541537936,"d":"0.61"},"up","no"]
["ENSG00000122515","ZMIZ2","ENST00000413916;ENST00000478045;ENST00000492001;ENST00000480964;ENST00000482322;ENST00000492558;ENST00000441627;ENST00000309315;ENST00000457123;ENST00000463931;ENST00000615423","GO:0005634(nucleus);GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0005654(nucleoplasm);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0005739(mitochondrion);GO:0005515(protein binding);GO:0030374(ligand-dependent nuclear receptor transcription coactivator activity);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0043596(nuclear replication fork);GO:0043596(nuclear replication fork)","NA","NA","NA","zinc finger MIZ-type containing 2 [Source:HGNC Symbol;Acc:HGNC:22229]",{"v":3.58571035495299,"d":"3.59"},{"v":1.3426481363946,"d":"1.34"},{"v":2.67062550325483,"d":"2.67"},{"v":1.41717768376903,"d":"1.42"},{"v":0.0843800956602765,"d":"0.08"},{"v":0.611451541537936,"d":"0.61"},"up","no"]
["MSTRG.5420","CIB1","ENST00000328649;ENST00000612800","GO:0005737(cytoplasm);GO:0005634(nucleus);GO:0016020(membrane);GO:0046872(metal ion binding);GO:0005654(nucleoplasm);GO:0005509(calcium ion binding);GO:0007155(cell adhesion);GO:0005794(Golgi apparatus);GO:0051301(cell division);GO:0005886(plasma membrane);GO:0005856(cytoskeleton);GO:0042995(cell projection);GO:0005515(protein binding);GO:0007049(cell cycle);GO:0006915(apoptotic process);GO:0048471(perinuclear region of cytoplasm);GO:0030154(cell differentiation);GO:0071901(negative regulation of protein serine/threonine kinase activity);GO:0007283(spermatogenesis);GO:0005813(centrosome);GO:0005815(microtubule organizing center);GO:0030027(lamellipodium);GO:0030426(growth cone);GO:0070062(extracellular exosome);GO:0001934(positive regulation of protein phosphorylation);GO:0071902(positive regulation of protein serine/threonine kinase activity);GO:0071944(cell periphery);GO:0008285(negative regulation of cell proliferation);GO:0042383(sarcolemma);GO:0032587(ruffle membrane);GO:0030335(positive regulation of cell migration);GO:0090314(positive regulation of protein targeting to membrane);GO:0071356(cellular response to tumor necrosis factor);GO:0006469(negative regulation of protein kinase activity);GO:0008284(positive regulation of cell proliferation);GO:0042127(regulation of cell proliferation);GO:0043005(neuron projection);GO:0043066(negative regulation of apoptotic process);GO:0016324(apical plasma membrane);GO:0051092(positive regulation of NF-kappaB transcription factor activity);GO:0070374(positive regulation of ERK1 and ERK2 cascade);GO:0001933(negative regulation of protein phosphorylation);GO:0031982(vesicle);GO:0001525(angiogenesis);GO:0051302(regulation of cell division);GO:0030307(positive regulation of cell growth);GO:0001954(positive regulation of cell-matrix adhesion);GO:0051898(negative regulation of protein kinase B signaling);GO:0002931(response to ischemia);GO:0097191(extrinsic apoptotic signaling pathway);GO:0005783(endoplasmic reticulum);GO:0090004(positive regulation of establishment of protein localization to plasma membrane);GO:0010977(negative regulation of neuron projection development);GO:0071363(cellular response to growth factor stimulus);GO:0043025(neuronal cell body);GO:0006302(double-strand break repair);GO:0090050(positive regulation of cell migration involved in sprouting angiogenesis);GO:0007026(negative regulation of microtubule depolymerization);GO:0007286(spermatid development);GO:0043085(positive regulation of catalytic activity);GO:0006974(cellular response to DNA damage stimulus);GO:0030220(platelet formation);GO:1900026(positive regulation of substrate adhesion-dependent cell spreading);GO:0043495(protein anchor);GO:0045653(negative regulation of megakaryocyte differentiation);GO:1990090(cellular response to nerve growth factor stimulus);GO:0033630(positive regulation of cell adhesion mediated by integrin);GO:0032433(filopodium tip);GO:0070886(positive regulation of calcineurin-NFAT signaling cascade);GO:0038163(thrombopoietin-mediated signaling pathway);GO:0017016(Ras GTPase binding);GO:0031122(cytoplasmic microtubule organization);GO:0008427(calcium-dependent protein kinase inhibitor activity);GO:0030291(protein serine/threonine kinase inhibitor activity);GO:0007113(endomitotic cell cycle);GO:2000256(positive regulation of male germ cell proliferation);GO:0008022(protein C-terminus binding);GO:0019901(protein kinase binding);GO:0044325(ion channel binding);GO:0030424(axon);GO:0030425(dendrite);GO:0030425(dendrite)","NA","NA","NA","calcium and integrin binding 1 [Source:HGNC Symbol;Acc:HGNC:16920]",{"v":34.2107114023409,"d":"34.21"},{"v":62.696319543526,"d":"62.70"},{"v":0.545657411015819,"d":"0.55"},{"v":-0.873932650249641,"d":"-0.87"},{"v":0.0844016895793775,"d":"0.08"},{"v":0.611451541537936,"d":"0.61"},"down","no"]
["MSTRG.15479","NSDHL","ENST00000370274;ENST00000440023","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005783(endoplasmic reticulum);GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0006629(lipid metabolic process);GO:0005789(endoplasmic reticulum membrane);GO:0006694(steroid biosynthetic process);GO:0008202(steroid metabolic process);GO:0016126(sterol biosynthetic process);GO:0003854(3-beta-hydroxy-delta5-steroid dehydrogenase activity);GO:0016616(oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor);GO:0005811(lipid particle);GO:0008203(cholesterol metabolic process);GO:0006695(cholesterol biosynthetic process);GO:0000252(C-3 sterol dehydrogenase (C-4 sterol decarboxylase) activity);GO:0047012(sterol-4-alpha-carboxylate 3-dehydrogenase (decarboxylating) activity);GO:0103066(-);GO:0001942(hair follicle development);GO:0007224(smoothened signaling pathway);GO:0060716(labyrinthine layer blood vessel development);GO:0060716(labyrinthine layer blood vessel development)","00100(Steroid biosynthesis);00100(Steroid biosynthesis)","K07748","EC:1.1.1.170","NAD(P) dependent steroid dehydrogenase-like [Source:HGNC Symbol;Acc:HGNC:13398]",{"v":2.43681988076152,"d":"2.44"},{"v":4.50083629759519,"d":"4.50"},{"v":0.541414910394213,"d":"0.54"},{"v":-0.885193475425397,"d":"-0.89"},{"v":0.0845804554377687,"d":"0.08"},{"v":0.612364606607735,"d":"0.61"},"down","no"]
["MSTRG.15413","SLC25A5","ENST00000317881;ENST00000475354;ENST00000460013;ENST00000463551","GO:0003723(RNA binding);GO:0006810(transport);GO:0005634(nucleus);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005215(transporter activity);GO:0055085(transmembrane transport);GO:0005739(mitochondrion);GO:0005743(mitochondrial inner membrane);GO:0005515(protein binding);GO:0007059(chromosome segregation);GO:0070062(extracellular exosome);GO:0016032(viral process);GO:0005887(integral component of plasma membrane);GO:0031012(extracellular matrix);GO:0008284(positive regulation of cell proliferation);GO:1901029(negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway);GO:0042645(mitochondrial nucleoid);GO:0050796(regulation of insulin secretion);GO:0031625(ubiquitin protein ligase binding);GO:0015866(ADP transport);GO:0071817(MMXD complex);GO:0005471(ATP:ADP antiporter activity);GO:0015207(adenine transmembrane transporter activity);GO:0015853(adenine transport);GO:0015867(ATP transport);GO:1990830(cellular response to leukemia inhibitory factor);GO:0043209(myelin sheath);GO:0045121(membrane raft);GO:0045121(membrane raft)","04020(Calcium signaling pathway);04022(cGMP - PKG signaling pathway);04217(Necroptosis);04218(Cellular senescence);05012(Parkinson's disease);05016(Huntington's disease);05166(HTLV-I infection);05166(HTLV-I infection)","K05863","NA","solute carrier family 25 member 5 [Source:HGNC Symbol;Acc:HGNC:10991]",{"v":44.780952682,"d":"44.78"},{"v":82.008852452,"d":"82.01"},{"v":0.546050229250683,"d":"0.55"},{"v":-0.872894429167433,"d":"-0.87"},{"v":0.0846640018725916,"d":"0.08"},{"v":0.612514865314134,"d":"0.61"},"down","no"]
["MSTRG.7678","TMIGD2","ENST00000301272;ENST00000595645;ENST00000600114","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005886(plasma membrane);GO:0007165(signal transduction);GO:0002377(immunoglobulin production);GO:0006955(immune response);GO:0005615(extracellular space);GO:0005515(protein binding);GO:0001819(positive regulation of cytokine production);GO:0015026(coreceptor activity);GO:0042104(positive regulation of activated T cell proliferation);GO:0045766(positive regulation of angiogenesis);GO:0031295(T cell costimulation);GO:0031295(T cell costimulation)","NA","NA","NA","transmembrane and immunoglobulin domain containing 2 [Source:HGNC Symbol;Acc:HGNC:28324]",{"v":4.46775857052298,"d":"4.47"},{"v":8.2338515,"d":"8.23"},{"v":0.542608592166495,"d":"0.54"},{"v":-0.882016202118582,"d":"-0.88"},{"v":0.0847066971234392,"d":"0.08"},{"v":0.612514865314134,"d":"0.61"},"down","no"]
["MSTRG.11889","TMEM154","ENST00000304385;MSTRG.11889.2;ENST00000613578;ENST00000504064;ENST00000510252","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016021(integral component of membrane)","NA","NA","NA","transmembrane protein 154 [Source:HGNC Symbol;Acc:HGNC:26489]",{"v":4.31539864394981,"d":"4.32"},{"v":1.61730186189412,"d":"1.62"},{"v":2.6682703740264,"d":"2.67"},{"v":1.41590486123905,"d":"1.42"},{"v":0.084762466897432,"d":"0.08"},{"v":0.612536731848089,"d":"0.61"},"up","no"]
["MSTRG.3060","CHD4","MSTRG.3060.5;MSTRG.3060.4;ENST00000544040;ENST00000357008;ENST00000545584;ENST00000540960;ENST00000542717;ENST00000536999;ENST00000535717;ENST00000544484;ENST00000545942;ENST00000536301;ENST00000545083;ENST00000430771;ENST00000537634","GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0005524(ATP binding);GO:0008017(microtubule binding);GO:0006325(chromatin organization);GO:0051225(spindle assembly);GO:0016581(NuRD complex);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0000166(nucleotide binding);GO:0016787(hydrolase activity);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0016569(covalent chromatin modification);GO:0016575(histone deacetylation);GO:0004386(helicase activity);GO:0032508(DNA duplex unwinding);GO:0003677(DNA binding);GO:0000790(nuclear chromatin);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0005654(nucleoplasm);GO:0005813(centrosome);GO:0005815(microtubule organizing center);GO:0043234(protein complex);GO:1901796(regulation of signal transduction by p53 class mediator);GO:0004407(histone deacetylase activity);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0004003(ATP-dependent DNA helicase activity);GO:0001103(RNA polymerase II repressing transcription factor binding);GO:0008270(zinc ion binding);GO:0042826(histone deacetylase binding);GO:0031492(nucleosomal DNA binding);GO:0043044(ATP-dependent chromatin remodeling);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:0000980(RNA polymerase II distal enhancer sequence-specific DNA binding);GO:0008134(transcription factor binding);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0072553(terminal button organization);GO:0032993(protein-DNA complex);GO:0032993(protein-DNA complex)","05203(Viral carcinogenesis);05165(Human papillomavirus infection);05165(Human papillomavirus infection)","K11643","EC:3.6.4.12","chromodomain helicase DNA binding protein 4 [Source:HGNC Symbol;Acc:HGNC:1919]",{"v":23.0274028778432,"d":"23.03"},{"v":8.66022444072786,"d":"8.66"},{"v":2.65898453734622,"d":"2.66"},{"v":1.41087538759092,"d":"1.41"},{"v":0.0849782587560852,"d":"0.08"},{"v":0.613360675069941,"d":"0.61"},"up","no"]
["MSTRG.4280","EMC9","ENST00000558045;ENST00000560403;ENST00000419198;ENST00000559101;ENST00000216799;ENST00000560600;ENST00000558200","GO:0005737(cytoplasm);GO:0005515(protein binding);GO:0072546(ER membrane protein complex);GO:0072546(ER membrane protein complex)","NA","NA","NA","ER membrane protein complex subunit 9 [Source:HGNC Symbol;Acc:HGNC:20273]",{"v":0.837326993073048,"d":"0.84"},{"v":1.59854619710327,"d":"1.60"},{"v":0.523805314222617,"d":"0.52"},{"v":-0.932897398383801,"d":"-0.93"},{"v":0.0849821171262839,"d":"0.08"},{"v":0.613360675069941,"d":"0.61"},"down","no"]
["ENSG00000136243","NUPL2","ENST00000258742;ENST00000477844;ENST00000410002;ENST00000413919;ENST00000487595;ENST00000486136;ENST00000437140;ENST00000485250;ENST00000548367;ENST00000497500;ENST00000489145;ENST00000438012","GO:0003723(RNA binding);GO:0006810(transport);GO:0051028(mRNA transport);GO:0005634(nucleus);GO:0016020(membrane);GO:0015031(protein transport);GO:0046872(metal ion binding);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0005643(nuclear pore);GO:0075733(intracellular transport of virus);GO:0043657(host cell);GO:0005635(nuclear envelope);GO:0031965(nuclear membrane);GO:0005515(protein binding);GO:0006611(protein export from nucleus);GO:0016032(viral process);GO:0006406(mRNA export from nucleus);GO:0016925(protein sumoylation);GO:0060964(regulation of gene silencing by miRNA);GO:0005049(nuclear export signal receptor activity);GO:0006110(regulation of glycolytic process);GO:0006409(tRNA export from nucleus);GO:0007077(mitotic nuclear envelope disassembly);GO:0019083(viral transcription);GO:1900034(regulation of cellular response to heat);GO:1900034(regulation of cellular response to heat)","03013(RNA transport);03013(RNA transport)","K14321","NA","nucleoporin like 2 [Source:HGNC Symbol;Acc:HGNC:17010]",{"v":1.31506172766835,"d":"1.32"},{"v":2.42885812986716,"d":"2.43"},{"v":0.541432087571238,"d":"0.54"},{"v":-0.885147704548884,"d":"-0.89"},{"v":0.0851486237503247,"d":"0.09"},{"v":0.614180725225168,"d":"0.61"},"down","no"]
["MSTRG.8453","EPN1","ENST00000270460;ENST00000085079;ENST00000591743;ENST00000586194;ENST00000411543","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0005905(clathrin-coated pit);GO:0008289(lipid binding);GO:0006897(endocytosis);GO:0061024(membrane organization);GO:0042059(negative regulation of epidermal growth factor receptor signaling pathway);GO:0001701(in utero embryonic development);GO:0007219(Notch signaling pathway);GO:0007565(female pregnancy);GO:0048568(embryonic organ development);GO:0048568(embryonic organ development)","04144(Endocytosis);04144(Endocytosis)","K12471","NA","epsin 1 [Source:HGNC Symbol;Acc:HGNC:21604]",{"v":2.09933456936876,"d":"2.10"},{"v":0.788462413374205,"d":"0.79"},{"v":2.6625677188399,"d":"2.66"},{"v":1.41281821881907,"d":"1.41"},{"v":0.0852119627818024,"d":"0.09"},{"v":0.614256066905693,"d":"0.61"},"up","no"]
["ENSG00000106355","LSM5","ENST00000450169;ENST00000409952;ENST00000223084;ENST00000409292;ENST00000409987;ENST00000410044;ENST00000409909;ENST00000409782;ENST00000468872;ENST00000480956","GO:0003723(RNA binding);GO:0006397(mRNA processing);GO:0008380(RNA splicing);GO:0005634(nucleus);GO:0030529(intracellular ribonucleoprotein complex);GO:0005515(protein binding);GO:0005681(spliceosomal complex);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0000398(mRNA splicing, via spliceosome);GO:0046540(U4/U6 x U5 tri-snRNP complex);GO:0043928(exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay);GO:1990726(Lsm1-7-Pat1 complex);GO:0005688(U6 snRNP);GO:0000956(nuclear-transcribed mRNA catabolic process);GO:0000956(nuclear-transcribed mRNA catabolic process)","03040(Spliceosome);03018(RNA degradation);03018(RNA degradation)","K12624","NA","LSM5 homolog, U6 small nuclear RNA and mRNA degradation associated [Source:HGNC Symbol;Acc:HGNC:17162]",{"v":1.36802491703893,"d":"1.37"},{"v":2.51675362156988,"d":"2.52"},{"v":0.543567278622051,"d":"0.54"},{"v":-0.879469482767599,"d":"-0.88"},{"v":0.0854141247767728,"d":"0.09"},{"v":0.615331408829195,"d":"0.62"},"down","no"]
["MSTRG.401","PHC2;MIR3605","ENST00000373418;MSTRG.401.3;MSTRG.401.1;ENST00000467894;ENST00000459964;ENST00000373422;ENST00000257118;MSTRG.401.8;ENST00000486897;ENST00000583214;ENST00000493483;ENST00000431992;ENST00000473158;ENST00000485928","GO:0005634(nucleus);GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0005654(nucleoplasm);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0007275(multicellular organism development);GO:0042802(identical protein binding);GO:0031519(PcG protein complex);GO:0035102(PRC1 complex);GO:0007283(spermatogenesis);GO:0000792(heterochromatin);GO:0005615(extracellular space);GO:0000792(heterochromatin)","NA","NA","NA","polyhomeotic homolog 2 [Source:HGNC Symbol;Acc:HGNC:3183];microRNA 3605 [Source:HGNC Symbol;Acc:HGNC:38922]",{"v":36.1238849059861,"d":"36.12"},{"v":13.6073993428411,"d":"13.61"},{"v":2.65472365408244,"d":"2.65"},{"v":1.40856169016888,"d":"1.41"},{"v":0.0855177784828332,"d":"0.09"},{"v":0.615429798916465,"d":"0.62"},"up","no"]
["ENSG00000122971","ACADS","ENST00000242592;ENST00000411593;ENST00000539690","GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0016491(oxidoreductase activity);GO:0050660(flavin adenine dinucleotide binding);GO:0055114(oxidation-reduction process);GO:0016627(oxidoreductase activity, acting on the CH-CH group of donors);GO:0005739(mitochondrion);GO:0006629(lipid metabolic process);GO:0008152(metabolic process);GO:0006631(fatty acid metabolic process);GO:0005759(mitochondrial matrix);GO:0003995(acyl-CoA dehydrogenase activity);GO:0006635(fatty acid beta-oxidation);GO:0004085(butyryl-CoA dehydrogenase activity);GO:0004085(butyryl-CoA dehydrogenase activity)","00650(Butanoate metabolism);00071(Fatty acid degradation);00280(Valine, leucine and isoleucine degradation);00280(Valine, leucine and isoleucine degradation)","K00248","EC:1.3.8.1","acyl-CoA dehydrogenase, C-2 to C-3 short chain [Source:HGNC Symbol;Acc:HGNC:90]",{"v":1.97531527039275,"d":"1.98"},{"v":3.62888044939577,"d":"3.63"},{"v":0.544331867069815,"d":"0.54"},{"v":-0.877441595995379,"d":"-0.88"},{"v":0.0856741808116512,"d":"0.09"},{"v":0.615429798916465,"d":"0.62"},"down","no"]
["ENSG00000115808","STRN","ENST00000263918;ENST00000379213;ENST00000495595","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0042995(cell projection);GO:0005515(protein binding);GO:0016055(Wnt signaling pathway);GO:0045211(postsynaptic membrane);GO:0005516(calmodulin binding);GO:0005923(bicellular tight junction);GO:0000159(protein phosphatase type 2A complex);GO:0008285(negative regulation of cell proliferation);GO:0030331(estrogen receptor binding);GO:0014069(postsynaptic density);GO:0043197(dendritic spine);GO:0016358(dendrite development);GO:0032403(protein complex binding);GO:0070830(bicellular tight junction assembly);GO:0051721(protein phosphatase 2A binding);GO:0070016(armadillo repeat domain binding);GO:0007626(locomotory behavior);GO:0043025(neuronal cell body);GO:0043025(neuronal cell body)","NA","NA","NA","striatin [Source:HGNC Symbol;Acc:HGNC:11424]",{"v":4.74058778765728,"d":"4.74"},{"v":1.7834174657879,"d":"1.78"},{"v":2.65814812212962,"d":"2.66"},{"v":1.41042149931228,"d":"1.41"},{"v":0.0856951482226277,"d":"0.09"},{"v":0.615429798916465,"d":"0.62"},"up","no"]
["MSTRG.5857","BCL7C;AC135048.2","ENST00000215115;ENST00000572628;ENST00000380317;ENST00000572471;ENST00000574418","GO:0006915(apoptotic process);GO:0006915(apoptotic process)","NA","NA","NA","BCL tumor suppressor 7C [Source:HGNC Symbol;Acc:HGNC:1006]",{"v":1.45053882466477,"d":"1.45"},{"v":2.67040039719626,"d":"2.67"},{"v":0.543191510227357,"d":"0.54"},{"v":-0.880467163626893,"d":"-0.88"},{"v":0.0856989036268692,"d":"0.09"},{"v":0.615429798916465,"d":"0.62"},"down","no"]
["MSTRG.9981","BACH1;LINC00189","ENST00000399921;ENST00000286800;ENST00000447125;ENST00000435072;ENST00000547141;ENST00000550131;ENST00000422809;ENST00000548467;ENST00000548219;ENST00000451655;ENST00000447177;MSTRG.9981.9;ENST00000420364","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0006355(regulation of transcription, DNA-templated);GO:0006366(transcription from RNA polymerase II promoter);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0016567(protein ubiquitination);GO:0005829(cytosol);GO:0005515(protein binding);GO:0020037(heme binding);GO:0004842(ubiquitin-protein transferase activity);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0031463(Cul3-RING ubiquitin ligase complex);GO:0000980(RNA polymerase II distal enhancer sequence-specific DNA binding);GO:0001078(transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0000083(regulation of transcription involved in G1/S transition of mitotic cell cycle);GO:0000117(regulation of transcription involved in G2/M transition of mitotic cell cycle);GO:0006281(DNA repair);GO:0061418(regulation of transcription from RNA polymerase II promoter in response to hypoxia);GO:0001205(transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding);GO:0001206(transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0045944(positive regulation of transcription from RNA polymerase II promoter)","NA","NA","NA","BTB domain and CNC homolog 1 [Source:HGNC Symbol;Acc:HGNC:935];long intergenic non-protein coding RNA 189 [Source:HGNC Symbol;Acc:HGNC:18461]",{"v":26.8800276429654,"d":"26.88"},{"v":10.1293099970859,"d":"10.13"},{"v":2.65368792649238,"d":"2.65"},{"v":1.40799871985124,"d":"1.41"},{"v":0.0857700313209285,"d":"0.09"},{"v":0.615429798916465,"d":"0.62"},"up","no"]
["MSTRG.10366","SF3A1","ENST00000215793;ENST00000447376;ENST00000411423;ENST00000471037;ENST00000496189;ENST00000498259;ENST00000471342;ENST00000463818;ENST00000485618;ENST00000444440","GO:0003723(RNA binding);GO:0006396(RNA processing);GO:0006397(mRNA processing);GO:0008380(RNA splicing);GO:0005634(nucleus);GO:0016607(nuclear speck);GO:0005515(protein binding);GO:0005681(spliceosomal complex);GO:0005654(nucleoplasm);GO:0000381(regulation of alternative mRNA splicing, via spliceosome);GO:0000398(mRNA splicing, via spliceosome);GO:0071013(catalytic step 2 spliceosome);GO:0071004(U2-type prespliceosome);GO:0000389(mRNA 3'-splice site recognition);GO:0005684(U2-type spliceosomal complex);GO:0005686(U2 snRNP);GO:0005686(U2 snRNP)","03040(Spliceosome);03040(Spliceosome)","K12825","NA","splicing factor 3a subunit 1 [Source:HGNC Symbol;Acc:HGNC:10765]",{"v":23.3750330271765,"d":"23.38"},{"v":8.81290347811661,"d":"8.81"},{"v":2.6523645794169,"d":"2.65"},{"v":1.40727909398978,"d":"1.41"},{"v":0.0857800675290681,"d":"0.09"},{"v":0.615429798916465,"d":"0.62"},"up","no"]
["ENSG00000105409","ATP1A3","ENST00000441343;ENST00000602133;ENST00000485672;ENST00000302102;ENST00000545399","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0016787(hydrolase activity);GO:0006813(potassium ion transport);GO:0006814(sodium ion transport);GO:0005391(sodium:potassium-exchanging ATPase activity);GO:0010248(establishment or maintenance of transmembrane electrochemical gradient);GO:0090662(ATP hydrolysis coupled transmembrane transport);GO:0006810(transport);GO:0046872(metal ion binding);GO:0005794(Golgi apparatus);GO:0005783(endoplasmic reticulum);GO:0006811(ion transport);GO:0005886(plasma membrane);GO:0045202(synapse);GO:0034220(ion transmembrane transport);GO:1903779(regulation of cardiac conduction);GO:0005890(sodium:potassium-exchanging ATPase complex);GO:0043025(neuronal cell body);GO:1903561(extracellular vesicle);GO:0051087(chaperone binding);GO:0010107(potassium ion import);GO:1990239(steroid hormone binding);GO:0006883(cellular sodium ion homeostasis);GO:0030007(cellular potassium ion homeostasis);GO:0036376(sodium ion export from cell);GO:0071383(cellular response to steroid hormone stimulus);GO:0086064(cell communication by electrical coupling involved in cardiac conduction);GO:1903416(response to glycoside);GO:0032809(neuronal cell body membrane);GO:0060075(regulation of resting membrane potential);GO:0030424(axon);GO:0001540(amyloid-beta binding);GO:0031748(D1 dopamine receptor binding);GO:0043395(heparan sulfate proteoglycan binding);GO:0086037(sodium:potassium-exchanging ATPase activity involved in regulation of cardiac muscle cell membrane potential);GO:0007613(memory);GO:0008344(adult locomotory behavior);GO:0008542(visual learning);GO:0021987(cerebral cortex development);GO:0035235(ionotropic glutamate receptor signaling pathway);GO:0042493(response to drug);GO:0060048(cardiac muscle contraction);GO:0071300(cellular response to retinoic acid);GO:0086036(regulation of cardiac muscle cell membrane potential);GO:0097067(cellular response to thyroid hormone stimulus);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0042383(sarcolemma);GO:0043209(myelin sheath);GO:0044326(dendritic spine neck);GO:0044327(dendritic spine head);GO:0044327(dendritic spine head)","04024(cAMP signaling pathway);04022(cGMP - PKG signaling pathway);04911(Insulin secretion);04918(Thyroid hormone synthesis);04919(Thyroid hormone signaling pathway);04925(Aldosterone synthesis and secretion);04260(Cardiac muscle contraction);04261(Adrenergic signaling in cardiomyocytes);04970(Salivary secretion);04971(Gastric acid secretion);04972(Pancreatic secretion);04976(Bile secretion);04973(Carbohydrate digestion and absorption);04974(Protein digestion and absorption);04978(Mineral absorption);04960(Aldosterone-regulated sodium reabsorption);04961(Endocrine and other factor-regulated calcium reabsorption);04964(Proximal tubule bicarbonate reclamation);04964(Proximal tubule bicarbonate reclamation)","K01539","EC:3.6.3.9","ATPase Na+/K+ transporting subunit alpha 3 [Source:HGNC Symbol;Acc:HGNC:801]",{"v":1.15551065516591,"d":"1.16"},{"v":0.426405072021116,"d":"0.43"},{"v":2.70988956507696,"d":"2.71"},{"v":1.43823405926837,"d":"1.44"},{"v":0.0858077662079925,"d":"0.09"},{"v":0.615429798916465,"d":"0.62"},"up","no"]
["MSTRG.5739","NDUFAB1","ENST00000007516;ENST00000484769;ENST00000562133;ENST00000570319;ENST00000567761","GO:0005654(nucleoplasm);GO:0055114(oxidation-reduction process);GO:0005739(mitochondrion);GO:0006629(lipid metabolic process);GO:0006631(fatty acid metabolic process);GO:0006633(fatty acid biosynthetic process);GO:0005759(mitochondrial matrix);GO:0070469(respiratory chain);GO:0009249(protein lipoylation);GO:0005509(calcium ion binding);GO:0031966(mitochondrial membrane);GO:0005515(protein binding);GO:0032981(mitochondrial respiratory chain complex I assembly);GO:0005829(cytosol);GO:0034641(cellular nitrogen compound metabolic process);GO:0008137(NADH dehydrogenase (ubiquinone) activity);GO:0006120(mitochondrial electron transport, NADH to ubiquinone);GO:0005747(mitochondrial respiratory chain complex I);GO:0005743(mitochondrial inner membrane);GO:0000035(acyl binding);GO:0000036(ACP phosphopantetheine attachment site binding involved in fatty acid biosynthetic process);GO:0005504(fatty acid binding);GO:0031177(phosphopantetheine binding);GO:0006635(fatty acid beta-oxidation);GO:0009245(lipid A biosynthetic process);GO:0009245(lipid A biosynthetic process)","00190(Oxidative phosphorylation);04723(Retrograde endocannabinoid signaling);05010(Alzheimer's disease);05012(Parkinson's disease);05016(Huntington's disease);04932(Non-alcoholic fatty liver disease (NAFLD));04932(Non-alcoholic fatty liver disease (NAFLD))","K03955","NA","NADH:ubiquinone oxidoreductase subunit AB1 [Source:HGNC Symbol;Acc:HGNC:7694]",{"v":6.8465083325,"d":"6.85"},{"v":12.5580888225,"d":"12.56"},{"v":0.545187124352337,"d":"0.55"},{"v":-0.875176604373696,"d":"-0.88"},{"v":0.0858572111561976,"d":"0.09"},{"v":0.615429798916465,"d":"0.62"},"down","no"]
["MSTRG.1826","RPS24","MSTRG.1826.13;ENST00000478655;ENST00000372360;ENST00000360830;ENST00000480662;ENST00000464716;ENST00000435275;ENST00000440692;ENST00000476545;ENST00000465692;ENST00000475468;ENST00000613865;ENST00000466129;ENST00000482069;ENST00000485708","GO:0003723(RNA binding);GO:0005634(nucleus);GO:0016020(membrane);GO:0006412(translation);GO:0030529(intracellular ribonucleoprotein complex);GO:0005622(intracellular);GO:0003735(structural constituent of ribosome);GO:0005840(ribosome);GO:0022627(cytosolic small ribosomal subunit);GO:0006364(rRNA processing);GO:0042274(ribosomal small subunit biogenesis);GO:0000462(maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA));GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0006413(translational initiation);GO:0031369(translation initiation factor binding);GO:0000184(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay);GO:0019083(viral transcription);GO:0006614(SRP-dependent cotranslational protein targeting to membrane);GO:0034101(erythrocyte homeostasis);GO:0015935(small ribosomal subunit);GO:0015935(small ribosomal subunit)","03010(Ribosome);03010(Ribosome)","K02974","NA","ribosomal protein S24 [Source:HGNC Symbol;Acc:HGNC:10411]",{"v":59.4616067809868,"d":"59.46"},{"v":108.448965034497,"d":"108.45"},{"v":0.548291141018012,"d":"0.55"},{"v":-0.866985931324936,"d":"-0.87"},{"v":0.085904736419839,"d":"0.09"},{"v":0.615429798916465,"d":"0.62"},"down","no"]
["MSTRG.3349","TUBA1A","ENST00000550767;ENST00000301071;ENST00000548363;ENST00000546918;ENST00000295766;ENST00000552924;ENST00000550811;ENST00000550254;ENST00000547939","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005525(GTP binding);GO:0000166(nucleotide binding);GO:0003924(GTPase activity);GO:0015630(microtubule cytoskeleton);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0005200(structural constituent of cytoskeleton);GO:0007010(cytoskeleton organization);GO:0005874(microtubule);GO:0007017(microtubule-based process);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0055037(recycling endosome);GO:0000086(G2/M transition of mitotic cell cycle);GO:0010389(regulation of G2/M transition of mitotic cell cycle);GO:0097711(ciliary basal body docking);GO:0036464(cytoplasmic ribonucleoprotein granule);GO:0005198(structural molecule activity);GO:0030705(cytoskeleton-dependent intracellular transport);GO:0051301(cell division);GO:0019904(protein domain specific binding);GO:0005881(cytoplasmic microtubule);GO:0043209(myelin sheath);GO:0045121(membrane raft);GO:0045121(membrane raft)","04145(Phagosome);04210(Apoptosis);04530(Tight junction);04540(Gap junction);05130(Pathogenic Escherichia coli infection);05130(Pathogenic Escherichia coli infection)","K07374","NA","tubulin alpha 1a [Source:HGNC Symbol;Acc:HGNC:20766]",{"v":72.2387794130371,"d":"72.24"},{"v":131.739436781643,"d":"131.74"},{"v":0.548345895335595,"d":"0.55"},{"v":-0.866841865823056,"d":"-0.87"},{"v":0.0859918302294644,"d":"0.09"},{"v":0.615614241516794,"d":"0.62"},"down","no"]
["ENSG00000158186","MRAS","ENST00000289104;ENST00000614350;ENST00000423968;ENST00000478647;ENST00000461114;ENST00000475711","GO:0005622(intracellular);GO:0016020(membrane);GO:0005525(GTP binding);GO:0000166(nucleotide binding);GO:0007165(signal transduction);GO:0003924(GTPase activity);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0070062(extracellular exosome);GO:0007275(multicellular organism development);GO:0007517(muscle organ development);GO:0030742(GTP-dependent protein binding);GO:0007265(Ras protein signal transduction);GO:0030036(actin cytoskeleton organization);GO:1990830(cellular response to leukemia inhibitory factor);GO:1990830(cellular response to leukemia inhibitory factor)","04014(Ras signaling pathway);04015(Rap1 signaling pathway);04010(MAPK signaling pathway);04371(Apelin signaling pathway);04072(Phospholipase D signaling pathway);04140(Autophagy - animal);04137(Mitophagy - animal);04218(Cellular senescence);04810(Regulation of actin cytoskeleton);05205(Proteoglycans in cancer);05166(HTLV-I infection);05166(HTLV-I infection)","K07831","NA","muscle RAS oncogene homolog [Source:HGNC Symbol;Acc:HGNC:7227]",{"v":0.363342718303221,"d":"0.36"},{"v":0.679298694265515,"d":"0.68"},{"v":0.534879164895322,"d":"0.53"},{"v":-0.902715087291587,"d":"-0.90"},{"v":0.0860592362811154,"d":"0.09"},{"v":0.615614241516794,"d":"0.62"},"down","no"]
["MSTRG.174","PRDM2","ENST00000413440;ENST00000235372;ENST00000487453;ENST00000491815;ENST00000502727;ENST00000376048;ENST00000343137;ENST00000505823;MSTRG.174.2;ENST00000491134;ENST00000484063;ENST00000503842","GO:0005634(nucleus);GO:0003676(nucleic acid binding);GO:0005794(Golgi apparatus);GO:0046872(metal ion binding);GO:0008168(methyltransferase activity);GO:0016740(transferase activity);GO:0032259(methylation);GO:0006355(regulation of transcription, DNA-templated);GO:0006366(transcription from RNA polymerase II promoter);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0008270(zinc ion binding);GO:0018024(histone-lysine N-methyltransferase activity);GO:0034968(histone lysine methylation);GO:0001228(transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0000977(RNA polymerase II regulatory region sequence-specific DNA binding);GO:0008340(determination of adult lifespan);GO:0008340(determination of adult lifespan)","00310(Lysine degradation);00310(Lysine degradation)","K11432","EC:2.1.1.43","PR/SET domain 2 [Source:HGNC Symbol;Acc:HGNC:9347]",{"v":7.93957560505356,"d":"7.94"},{"v":2.99369541920718,"d":"2.99"},{"v":2.65209865843874,"d":"2.65"},{"v":1.40713444490482,"d":"1.41"},{"v":0.0860895141843859,"d":"0.09"},{"v":0.615614241516794,"d":"0.62"},"up","no"]
["ENSG00000068654","POLR1A","ENST00000263857;ENST00000496892;ENST00000486964;ENST00000483538;ENST00000409681;ENST00000492034;ENST00000462078","GO:0005634(nucleus);GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0016740(transferase activity);GO:0003677(DNA binding);GO:0006351(transcription, DNA-templated);GO:0005515(protein binding);GO:0003899(DNA-directed 5'-3' RNA polymerase activity);GO:0016779(nucleotidyltransferase activity);GO:0005730(nucleolus);GO:0005654(nucleoplasm);GO:0003682(chromatin binding);GO:0045815(positive regulation of gene expression, epigenetic);GO:0006361(transcription initiation from RNA polymerase I promoter);GO:0006362(transcription elongation from RNA polymerase I promoter);GO:0006363(termination of RNA polymerase I transcription);GO:0005736(DNA-directed RNA polymerase I complex);GO:0001054(RNA polymerase I activity);GO:1904750(negative regulation of protein localization to nucleolus);GO:1904750(negative regulation of protein localization to nucleolus)","00230(Purine metabolism);00240(Pyrimidine metabolism);03020(RNA polymerase);03020(RNA polymerase)","K02999","EC:2.7.7.6","RNA polymerase I subunit A [Source:HGNC Symbol;Acc:HGNC:17264]",{"v":1.70297747133664,"d":"1.70"},{"v":0.64120874325024,"d":"0.64"},{"v":2.65588622934923,"d":"2.66"},{"v":1.4091933470353,"d":"1.41"},{"v":0.0862562385929142,"d":"0.09"},{"v":0.616407039188203,"d":"0.62"},"up","no"]
["MSTRG.1918","MRPL43","ENST00000318364;ENST00000318325;ENST00000299179;ENST00000342071;ENST00000370234;ENST00000487059;ENST00000493646;ENST00000476012;ENST00000370241;ENST00000370236;ENST00000477279;ENST00000370242","GO:0003723(RNA binding);GO:0006412(translation);GO:0030529(intracellular ribonucleoprotein complex);GO:0005840(ribosome);GO:0005739(mitochondrion);GO:0005515(protein binding);GO:0003735(structural constituent of ribosome);GO:0005743(mitochondrial inner membrane);GO:0070125(mitochondrial translational elongation);GO:0070126(mitochondrial translational termination);GO:0005761(mitochondrial ribosome);GO:0005762(mitochondrial large ribosomal subunit);GO:0005762(mitochondrial large ribosomal subunit)","NA","NA","NA","mitochondrial ribosomal protein L43 [Source:HGNC Symbol;Acc:HGNC:14517]",{"v":3.50041771032746,"d":"3.50"},{"v":6.39484983403303,"d":"6.39"},{"v":0.547380751882309,"d":"0.55"},{"v":-0.869383390276147,"d":"-0.87"},{"v":0.0863714126538376,"d":"0.09"},{"v":0.616407039188203,"d":"0.62"},"down","no"]
["ENSG00000169891","REPS2","ENST00000357277;ENST00000303843;ENST00000469714;ENST00000470686","GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0005509(calcium ion binding);GO:0005515(protein binding);GO:0005829(cytosol);GO:0061024(membrane organization);GO:0006461(protein complex assembly);GO:0007173(epidermal growth factor receptor signaling pathway);GO:0007173(epidermal growth factor receptor signaling pathway)","NA","NA","NA","RALBP1 associated Eps domain containing 2 [Source:HGNC Symbol;Acc:HGNC:9963]",{"v":3.57152649102643,"d":"3.57"},{"v":1.34534504455839,"d":"1.35"},{"v":2.65472898976544,"d":"2.65"},{"v":1.40856458981369,"d":"1.41"},{"v":0.0864676653985251,"d":"0.09"},{"v":0.616407039188203,"d":"0.62"},"up","no"]
["MSTRG.4344","KLHL28","ENST00000396128;ENST00000556500;ENST00000553817;ENST00000556239;ENST00000557468;MSTRG.4344.5;ENST00000579157;ENST00000355081","GO:0016567(protein ubiquitination);GO:0004842(ubiquitin-protein transferase activity);GO:0031463(Cul3-RING ubiquitin ligase complex);GO:0031463(Cul3-RING ubiquitin ligase complex)","NA","NA","NA","kelch like family member 28 [Source:HGNC Symbol;Acc:HGNC:19741]",{"v":3.27563301139178,"d":"3.28"},{"v":1.23393183358098,"d":"1.23"},{"v":2.65463044411911,"d":"2.65"},{"v":1.40851103483515,"d":"1.41"},{"v":0.0866157434117425,"d":"0.09"},{"v":0.616407039188203,"d":"0.62"},"up","no"]
["MSTRG.2354","PHF21A","ENST00000418153;MSTRG.2354.3;ENST00000323180;MSTRG.2354.4;ENST00000530587;ENST00000527753;ENST00000529734;ENST00000524497;ENST00000525676;ENST00000528893;ENST00000532883;ENST00000532010;ENST00000532028;ENST00000530312;ENST00000531959;ENST00000527401;ENST00000534724;ENST00000525438;ENST00000534766;ENST00000525679;ENST00000533757;ENST00000529782","GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0016569(covalent chromatin modification);GO:0016575(histone deacetylation);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0003682(chromatin binding);GO:0005654(nucleoplasm);GO:0000977(RNA polymerase II regulatory region sequence-specific DNA binding);GO:0004407(histone deacetylase activity);GO:0042393(histone binding);GO:0007596(blood coagulation);GO:0003712(transcription cofactor activity);GO:1990391(DNA repair complex);GO:0000118(histone deacetylase complex);GO:0000118(histone deacetylase complex)","NA","NA","NA","PHD finger protein 21A [Source:HGNC Symbol;Acc:HGNC:24156]",{"v":6.24408680695497,"d":"6.24"},{"v":2.35246102193491,"d":"2.35"},{"v":2.65427854010486,"d":"2.65"},{"v":1.40831977513246,"d":"1.41"},{"v":0.0866351917573304,"d":"0.09"},{"v":0.616407039188203,"d":"0.62"},"up","no"]
["MSTRG.10319","GUCD1","ENST00000435822;ENST00000404664;ENST00000621833;ENST00000407471;ENST00000398245;ENST00000468170;ENST00000493099;ENST00000407973;ENST00000402766;ENST00000447813;ENST00000490810;ENST00000480272;ENST00000490922","GO:0005515(protein binding);GO:0005515(protein binding)","NA","NA","NA","guanylyl cyclase domain containing 1 [Source:HGNC Symbol;Acc:HGNC:14237]",{"v":13.8136199732833,"d":"13.81"},{"v":5.20559526760874,"d":"5.21"},{"v":2.65361006055101,"d":"2.65"},{"v":1.40795638689472,"d":"1.41"},{"v":0.0866425661138747,"d":"0.09"},{"v":0.616407039188203,"d":"0.62"},"up","no"]
["MSTRG.14950","RC3H2","ENST00000373670;ENST00000357244;ENST00000335387;ENST00000495727;ENST00000398671;ENST00000423239;ENST00000471874;ENST00000454740;ENST00000498479","GO:0003723(RNA binding);GO:0003729(mRNA binding);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0046872(metal ion binding);GO:0016740(transferase activity);GO:0016567(protein ubiquitination);GO:0003677(DNA binding);GO:0004842(ubiquitin-protein transferase activity);GO:0001782(B cell homeostasis);GO:0009791(post-embryonic development);GO:0010468(regulation of gene expression);GO:0010608(posttranscriptional regulation of gene expression);GO:0035264(multicellular organism growth);GO:0042098(T cell proliferation);GO:0043029(T cell homeostasis);GO:0048286(lung alveolus development);GO:0048535(lymph node development);GO:0048536(spleen development);GO:0060173(limb development);GO:0061470(T follicular helper cell differentiation);GO:1901224(positive regulation of NIK/NF-kappaB signaling);GO:0000932(P-body);GO:0009986(cell surface);GO:0000209(protein polyubiquitination);GO:0000209(protein polyubiquitination)","NA","NA","NA","ring finger and CCCH-type domains 2 [Source:HGNC Symbol;Acc:HGNC:21461]",{"v":3.24721419740147,"d":"3.25"},{"v":1.22245200303162,"d":"1.22"},{"v":2.65631222276911,"d":"2.66"},{"v":1.40942473093451,"d":"1.41"},{"v":0.0866882105917234,"d":"0.09"},{"v":0.616407039188203,"d":"0.62"},"up","no"]
["MSTRG.7380","SMCHD1","ENST00000320876;MSTRG.7380.2;ENST00000583800;ENST00000581383;ENST00000584897;ENST00000577880;ENST00000585229;ENST00000581631;ENST00000581711;ENST00000583344;ENST00000581226;ENST00000577300;ENST00000583441","GO:0005524(ATP binding);GO:0005694(chromosome);GO:0051276(chromosome organization);GO:0000784(nuclear chromosome, telomeric region);GO:0016887(ATPase activity);GO:0009048(dosage compensation by inactivation of X chromosome);GO:0043584(nose development);GO:0060821(inactivation of X chromosome by DNA methylation);GO:0001740(Barr body);GO:0001740(Barr body)","NA","NA","NA","structural maintenance of chromosomes flexible hinge domain containing 1 [Source:HGNC Symbol;Acc:HGNC:29090]",{"v":43.5767881816544,"d":"43.58"},{"v":16.4787999605242,"d":"16.48"},{"v":2.64441514467345,"d":"2.64"},{"v":1.40294868219607,"d":"1.40"},{"v":0.0867076197337424,"d":"0.09"},{"v":0.616407039188203,"d":"0.62"},"up","no"]
["MSTRG.3875","ULK1","ENST00000540647;ENST00000321867;ENST00000540568;ENST00000537421;ENST00000542313;ENST00000544718;ENST00000541761","GO:0005737(cytoplasm);GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0007165(signal transduction);GO:0005829(cytosol);GO:0005515(protein binding);GO:0006914(autophagy);GO:0034045(pre-autophagosomal structure membrane);GO:0005789(endoplasmic reticulum membrane);GO:0075044(autophagy of host cells involved in interaction with symbiont);GO:0061024(membrane organization);GO:0005776(autophagosome);GO:0046777(protein autophosphorylation);GO:0005741(mitochondrial outer membrane);GO:0032403(protein complex binding);GO:0031175(neuron projection development);GO:0048675(axon extension);GO:0016241(regulation of macroautophagy);GO:0008104(protein localization);GO:0016236(macroautophagy);GO:0000407(pre-autophagosomal structure);GO:1990316(ATG1/ULK1 kinase complex);GO:0032045(guanyl-nucleotide exchange factor complex);GO:0017137(Rab GTPase binding);GO:0051020(GTPase binding);GO:0007409(axonogenesis);GO:0018105(peptidyl-serine phosphorylation);GO:0018107(peptidyl-threonine phosphorylation);GO:0031102(neuron projection regeneration);GO:0031333(negative regulation of protein complex assembly);GO:0031669(cellular response to nutrient levels);GO:0042594(response to starvation);GO:0055037(recycling endosome);GO:0097629(extrinsic component of omegasome membrane);GO:0097632(extrinsic component of pre-autophagosomal structure membrane);GO:0097635(extrinsic component of autophagosome membrane);GO:0097635(extrinsic component of autophagosome membrane)","04152(AMPK signaling pathway);04150(mTOR signaling pathway);04140(Autophagy - animal);04137(Mitophagy - animal);04211(Longevity regulating pathway - mammal);04211(Longevity regulating pathway - mammal)","K21357","EC:2.7.11.1","unc-51 like autophagy activating kinase 1 [Source:HGNC Symbol;Acc:HGNC:12558]",{"v":6.75042276629863,"d":"6.75"},{"v":2.54499528575184,"d":"2.54"},{"v":2.65243036169492,"d":"2.65"},{"v":1.40731487436106,"d":"1.41"},{"v":0.0867913713707952,"d":"0.09"},{"v":0.616407039188203,"d":"0.62"},"up","no"]
["MSTRG.8981","COX5B","ENST00000494306;ENST00000258424;ENST00000491989;ENST00000464949","GO:0016020(membrane);GO:0046872(metal ion binding);GO:0005739(mitochondrion);GO:0005743(mitochondrial inner membrane);GO:0005515(protein binding);GO:0004129(cytochrome-c oxidase activity);GO:0005740(mitochondrial envelope);GO:0070062(extracellular exosome);GO:0006123(mitochondrial electron transport, cytochrome c to oxygen);GO:0007585(respiratory gaseous exchange);GO:0005751(mitochondrial respiratory chain complex IV);GO:0042776(mitochondrial ATP synthesis coupled proton transport);GO:0042776(mitochondrial ATP synthesis coupled proton transport)","00190(Oxidative phosphorylation);04260(Cardiac muscle contraction);05010(Alzheimer's disease);05012(Parkinson's disease);05016(Huntington's disease);04932(Non-alcoholic fatty liver disease (NAFLD));04932(Non-alcoholic fatty liver disease (NAFLD))","K02265","NA","cytochrome c oxidase subunit 5B [Source:HGNC Symbol;Acc:HGNC:2269]",{"v":16.1307766384455,"d":"16.13"},{"v":29.3940400458015,"d":"29.39"},{"v":0.548777119896097,"d":"0.55"},{"v":-0.865707762247895,"d":"-0.87"},{"v":0.0868454088497111,"d":"0.09"},{"v":0.616407039188203,"d":"0.62"},"down","no"]
["MSTRG.11832","AC093591.1","ENST00000491435","NA","NA","NA","NA",null,{"v":76.393127,"d":"76.39"},{"v":139.115265,"d":"139.12"},{"v":0.549135474097684,"d":"0.55"},{"v":-0.864765982636842,"d":"-0.86"},{"v":0.0869456662553039,"d":"0.09"},{"v":0.616407039188203,"d":"0.62"},"down","no"]
["MSTRG.8624","EIF2AK2","ENST00000233057;ENST00000390013;ENST00000411537;MSTRG.8624.5;ENST00000395127","GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0005829(cytosol);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0042981(regulation of apoptotic process);GO:0004713(protein tyrosine kinase activity);GO:0018108(peptidyl-tyrosine phosphorylation);GO:0009615(response to virus);GO:0005515(protein binding);GO:0004715(non-membrane spanning protein tyrosine kinase activity);GO:0048471(perinuclear region of cytoplasm);GO:0003725(double-stranded RNA binding);GO:0008285(negative regulation of cell proliferation);GO:0002376(immune system process);GO:0045087(innate immune response);GO:0051607(defense response to virus);GO:0001819(positive regulation of cytokine production);GO:0045071(negative regulation of viral genome replication);GO:0016032(viral process);GO:0017148(negative regulation of translation);GO:0009636(response to toxic substance);GO:0010998(regulation of translational initiation by eIF2 alpha phosphorylation);GO:0051092(positive regulation of NF-kappaB transcription factor activity);GO:0046777(protein autophosphorylation);GO:0032874(positive regulation of stress-activated MAPK cascade);GO:0032722(positive regulation of chemokine production);GO:0000186(activation of MAPKK activity);GO:1901224(positive regulation of NIK/NF-kappaB signaling);GO:0034198(cellular response to amino acid starvation);GO:0035455(response to interferon-alpha);GO:0004694(eukaryotic translation initiation factor 2alpha kinase activity);GO:0019888(protein phosphatase regulator activity);GO:0006412(translation);GO:0030683(evasion or tolerance by virus of host immune response);GO:0030968(endoplasmic reticulum unfolded protein response);GO:0033689(negative regulation of osteoblast proliferation);GO:0043066(negative regulation of apoptotic process);GO:1900225(regulation of NLRP3 inflammasome complex assembly);GO:1901532(regulation of hematopoietic progenitor cell differentiation);GO:1902033(regulation of hematopoietic stem cell proliferation);GO:1902036(regulation of hematopoietic stem cell differentiation);GO:0005840(ribosome);GO:0005840(ribosome)","04141(Protein processing in endoplasmic reticulum);04217(Necroptosis);05203(Viral carcinogenesis);05162(Measles);05164(Influenza A);05160(Hepatitis C);05168(Herpes simplex infection);05167(Kaposi's sarcoma-associated herpesvirus infection);05169(Epstein-Barr virus infection);05165(Human papillomavirus infection);05165(Human papillomavirus infection)","K16195","EC:2.7.11.1","eukaryotic translation initiation factor 2 alpha kinase 2 [Source:HGNC Symbol;Acc:HGNC:9437]",{"v":6.05994745912768,"d":"6.06"},{"v":2.29029816795313,"d":"2.29"},{"v":2.64592075561215,"d":"2.65"},{"v":1.40376985405901,"d":"1.40"},{"v":0.0869671838647988,"d":"0.09"},{"v":0.616407039188203,"d":"0.62"},"up","no"]
["MSTRG.3812","AC084018.1;AC084018.2","ENST00000609067;ENST00000613093","NA","NA","NA","NA",null,{"v":0.824200560458067,"d":"0.82"},{"v":0.298725592118558,"d":"0.30"},{"v":2.75905574280679,"d":"2.76"},{"v":1.46417460459207,"d":"1.46"},{"v":0.0869749557022458,"d":"0.09"},{"v":0.616407039188203,"d":"0.62"},"up","no"]
["MSTRG.11195","SRPRB","ENST00000481356;ENST00000484684;ENST00000466490;ENST00000466636;ENST00000494297","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005525(GTP binding);GO:0007264(small GTPase mediated signal transduction);GO:0000166(nucleotide binding);GO:0005622(intracellular);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0036498(IRE1-mediated unfolded protein response);GO:0005881(cytoplasmic microtubule);GO:0005047(signal recognition particle binding);GO:0005785(signal recognition particle receptor complex);GO:0005785(signal recognition particle receptor complex)","03060(Protein export);03060(Protein export)","K12272","NA","SRP receptor beta subunit [Source:HGNC Symbol;Acc:HGNC:24085]",{"v":1.98643439521531,"d":"1.99"},{"v":3.63369040358852,"d":"3.63"},{"v":0.546671338112231,"d":"0.55"},{"v":-0.871254357629222,"d":"-0.87"},{"v":0.0869919952014905,"d":"0.09"},{"v":0.616407039188203,"d":"0.62"},"down","no"]
["MSTRG.9643","TM9SF4","ENST00000398022;ENST00000495749;ENST00000450829;MSTRG.9643.2;ENST00000479591;ENST00000217315;ENST00000442842","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0007155(cell adhesion);GO:0005794(Golgi apparatus);GO:0005515(protein binding);GO:0005768(endosome);GO:0005769(early endosome);GO:0001666(response to hypoxia);GO:0006909(phagocytosis);GO:0051453(regulation of intracellular pH);GO:2000010(positive regulation of protein localization to cell surface);GO:0070863(positive regulation of protein exit from endoplasmic reticulum);GO:0070072(vacuolar proton-transporting V-type ATPase complex assembly);GO:0070072(vacuolar proton-transporting V-type ATPase complex assembly)","NA","NA","NA","transmembrane 9 superfamily member 4 [Source:HGNC Symbol;Acc:HGNC:30797]",{"v":10.2942864506002,"d":"10.29"},{"v":3.89013320295476,"d":"3.89"},{"v":2.64625551710701,"d":"2.65"},{"v":1.40395237207212,"d":"1.40"},{"v":0.0869965674011422,"d":"0.09"},{"v":0.616407039188203,"d":"0.62"},"up","no"]
["MSTRG.8744","USP34","ENST00000398571;ENST00000490552;ENST00000498268;ENST00000494867;ENST00000453734;ENST00000492882;ENST00000411912;ENST00000468703;ENST00000463046;ENST00000467128;ENST00000453133;ENST00000483672;ENST00000482250;ENST00000490527;ENST00000492604;ENST00000472689;ENST00000487547","GO:0016579(protein deubiquitination);GO:0016787(hydrolase activity);GO:0008233(peptidase activity);GO:0008234(cysteine-type peptidase activity);GO:0006508(proteolysis);GO:0006511(ubiquitin-dependent protein catabolic process);GO:0036459(thiol-dependent ubiquitinyl hydrolase activity);GO:0016055(Wnt signaling pathway);GO:0005515(protein binding);GO:0005829(cytosol);GO:0004843(thiol-dependent ubiquitin-specific protease activity);GO:0071108(protein K48-linked deubiquitination);GO:0090263(positive regulation of canonical Wnt signaling pathway);GO:0004197(cysteine-type endopeptidase activity);GO:0004197(cysteine-type endopeptidase activity)","NA","NA","NA","ubiquitin specific peptidase 34 [Source:HGNC Symbol;Acc:HGNC:20066]",{"v":7.7754002032,"d":"7.78"},{"v":2.94202520695172,"d":"2.94"},{"v":2.64287341414597,"d":"2.64"},{"v":1.40210732579016,"d":"1.40"},{"v":0.0874112201560451,"d":"0.09"},{"v":0.61860994192239,"d":"0.62"},"up","no"]
["ENSG00000135686","KLHL36","ENST00000325279;ENST00000564996;ENST00000258157;ENST00000564159;ENST00000567410;ENST00000565743","GO:0016567(protein ubiquitination);GO:0004842(ubiquitin-protein transferase activity);GO:0031463(Cul3-RING ubiquitin ligase complex);GO:0031463(Cul3-RING ubiquitin ligase complex)","NA","NA","NA","kelch like family member 36 [Source:HGNC Symbol;Acc:HGNC:17844]",{"v":1.8542870190095,"d":"1.85"},{"v":0.697428499149575,"d":"0.70"},{"v":2.65874856171,"d":"2.66"},{"v":1.41074734773859,"d":"1.41"},{"v":0.0874506740866223,"d":"0.09"},{"v":0.61860994192239,"d":"0.62"},"up","no"]
["MSTRG.7100","ERN1","ENST00000433197;ENST00000579249;ENST00000583028;ENST00000606895;ENST00000583896;ENST00000583077;ENST00000584041;ENST00000577567","GO:1904707(positive regulation of vascular smooth muscle cell proliferation);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0016787(hydrolase activity);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005515(protein binding);GO:0003824(catalytic activity);GO:0008152(metabolic process);GO:0006397(mRNA processing);GO:0006915(apoptotic process);GO:0090502(RNA phosphodiester bond hydrolysis, endonucleolytic);GO:0000287(magnesium ion binding);GO:0042802(identical protein binding);GO:0004540(ribonuclease activity);GO:0006986(response to unfolded protein);GO:0007050(cell cycle arrest);GO:0030176(integral component of endoplasmic reticulum membrane);GO:0019899(enzyme binding);GO:0042803(protein homodimerization activity);GO:0036498(IRE1-mediated unfolded protein response);GO:0035924(cellular response to vascular endothelial growth factor stimulus);GO:0071333(cellular response to glucose stimulus);GO:0016241(regulation of macroautophagy);GO:0030544(Hsp70 protein binding);GO:0034976(response to endoplasmic reticulum stress);GO:0033120(positive regulation of RNA splicing);GO:0004519(endonuclease activity);GO:0004521(endoribonuclease activity);GO:0005161(platelet-derived growth factor receptor binding);GO:0043531(ADP binding);GO:0051879(Hsp90 protein binding);GO:0001935(endothelial cell proliferation);GO:0006379(mRNA cleavage);GO:0006402(mRNA catabolic process);GO:0006987(activation of signaling protein activity involved in unfolded protein response);GO:0007257(activation of JUN kinase activity);GO:0030968(endoplasmic reticulum unfolded protein response);GO:0036289(peptidyl-serine autophosphorylation);GO:0046777(protein autophosphorylation);GO:0070054(mRNA splicing, via endonucleolytic cleavage and ligation);GO:0070055(mRNA endonucleolytic cleavage involved in unfolded protein response);GO:0070059(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress);GO:1900103(positive regulation of endoplasmic reticulum unfolded protein response);GO:1901142(insulin metabolic process);GO:1990579(peptidyl-serine trans-autophosphorylation);GO:0005637(nuclear inner membrane);GO:0005739(mitochondrion);GO:1990332(Ire1 complex);GO:1990597(AIP1-IRE1 complex);GO:1990604(IRE1-TRAF2-ASK1 complex);GO:1990630(IRE1-RACK1-PP2A complex);GO:1990630(IRE1-RACK1-PP2A complex)","04141(Protein processing in endoplasmic reticulum);04140(Autophagy - animal);04210(Apoptosis);05010(Alzheimer's disease);04932(Non-alcoholic fatty liver disease (NAFLD));04932(Non-alcoholic fatty liver disease (NAFLD))","K08852","EC:2.7.11.1;EC:3.1.26.-","endoplasmic reticulum to nucleus signaling 1 [Source:HGNC Symbol;Acc:HGNC:3449]",{"v":9.33756918722386,"d":"9.34"},{"v":3.53515675119661,"d":"3.54"},{"v":2.64134516356685,"d":"2.64"},{"v":1.40127284115983,"d":"1.40"},{"v":0.0875340914215694,"d":"0.09"},{"v":0.61860994192239,"d":"0.62"},"up","no"]
["ENSG00000137101","CD72","ENST00000490239;ENST00000259633;ENST00000378430;ENST00000482121;ENST00000378431;ENST00000470387;ENST00000463720;ENST00000612238;ENST00000396757;ENST00000465754;ENST00000477364","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0030246(carbohydrate binding);GO:0007165(signal transduction);GO:0005886(plasma membrane);GO:0005887(integral component of plasma membrane);GO:0005515(protein binding);GO:0007155(cell adhesion);GO:0004888(transmembrane signaling receptor activity);GO:0005102(receptor binding);GO:0005102(receptor binding)","04662(B cell receptor signaling pathway);04662(B cell receptor signaling pathway)","K06504","NA","CD72 molecule [Source:HGNC Symbol;Acc:HGNC:1696]",{"v":1.71157096780862,"d":"1.71"},{"v":3.14484402155936,"d":"3.14"},{"v":0.544246695885395,"d":"0.54"},{"v":-0.877667351030104,"d":"-0.88"},{"v":0.0876230551383297,"d":"0.09"},{"v":0.61860994192239,"d":"0.62"},"down","no"]
["MSTRG.13612","BLVRA","ENST00000402924;ENST00000265523;ENST00000453612;ENST00000486984;ENST00000424330","GO:0005737(cytoplasm);GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0005829(cytosol);GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0005515(protein binding);GO:0004074(biliverdin reductase activity);GO:0042167(heme catabolic process);GO:0070062(extracellular exosome);GO:0070062(extracellular exosome)","00860(Porphyrin and chlorophyll metabolism);00860(Porphyrin and chlorophyll metabolism)","K00214","EC:1.3.1.24","biliverdin reductase A [Source:HGNC Symbol;Acc:HGNC:1062]",{"v":3.97641525041186,"d":"3.98"},{"v":7.28426561724327,"d":"7.28"},{"v":0.545891028602652,"d":"0.55"},{"v":-0.873315107450987,"d":"-0.87"},{"v":0.0876233380416691,"d":"0.09"},{"v":0.61860994192239,"d":"0.62"},"down","no"]
["MSTRG.8869","CAPG","ENST00000409724;ENST00000449030;ENST00000263867;ENST00000409921;ENST00000491267;ENST00000453973;ENST00000415012;ENST00000439385;ENST00000447219;ENST00000409275;ENST00000483659;ENST00000471064;ENST00000459793;ENST00000409670","GO:0005737(cytoplasm);GO:0005634(nucleus);GO:0051015(actin filament binding);GO:0003779(actin binding);GO:0051016(barbed-end actin filament capping);GO:0051693(actin filament capping);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0042470(melanosome);GO:0005654(nucleoplasm);GO:0005730(nucleolus);GO:0045296(cadherin binding);GO:0070062(extracellular exosome);GO:0005814(centriole);GO:0019904(protein domain specific binding);GO:0006461(protein complex assembly);GO:0032403(protein complex binding);GO:0072686(mitotic spindle);GO:0090543(Flemming body);GO:0008290(F-actin capping protein complex);GO:0008290(F-actin capping protein complex)","NA","NA","NA","capping actin protein, gelsolin like [Source:HGNC Symbol;Acc:HGNC:1474]",{"v":15.1361413532796,"d":"15.14"},{"v":27.5052925665516,"d":"27.51"},{"v":0.550299231199098,"d":"0.55"},{"v":-0.861711781749843,"d":"-0.86"},{"v":0.0877577118082743,"d":"0.09"},{"v":0.61860994192239,"d":"0.62"},"down","no"]
["ENSG00000170100","ZNF778","ENST00000565877;ENST00000564906;ENST00000567651;ENST00000565414;ENST00000620195;ENST00000433976","GO:0003676(nucleic acid binding);GO:0006355(regulation of transcription, DNA-templated);GO:0005622(intracellular);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0005515(protein binding)","NA","NA","NA","zinc finger protein 778 [Source:HGNC Symbol;Acc:HGNC:26479]",{"v":0.0950980186285816,"d":"0.10"},{"v":0.183809606227269,"d":"0.18"},{"v":0.517372408224404,"d":"0.52"},{"v":-0.950724978590366,"d":"-0.95"},{"v":0.0878086761509663,"d":"0.09"},{"v":0.61860994192239,"d":"0.62"},"down","no"]
["MSTRG.5077","DMXL2","MSTRG.5077.2;ENST00000559769;ENST00000561079;ENST00000559059;ENST00000560421;ENST00000559062;ENST00000251076;ENST00000449909;ENST00000558124;ENST00000558507;ENST00000560211;ENST00000559868;ENST00000559498;ENST00000543779","GO:0016020(membrane);GO:0005615(extracellular space);GO:0030054(cell junction);GO:0045202(synapse);GO:0031410(cytoplasmic vesicle);GO:0030672(synaptic vesicle membrane);GO:0017137(Rab GTPase binding);GO:0007035(vacuolar acidification);GO:0070072(vacuolar proton-transporting V-type ATPase complex assembly);GO:0008021(synaptic vesicle);GO:0043291(RAVE complex);GO:0043291(RAVE complex)","NA","NA","NA","Dmx like 2 [Source:HGNC Symbol;Acc:HGNC:2938]",{"v":7.04825345827022,"d":"7.05"},{"v":2.66939454851042,"d":"2.67"},{"v":2.6403940407398,"d":"2.64"},{"v":1.40075324708386,"d":"1.40"},{"v":0.0878293174686538,"d":"0.09"},{"v":0.61860994192239,"d":"0.62"},"up","no"]
["ENSG00000268758","ADGRE4P","ENST00000600751;ENST00000639977;ENST00000640515","NA","NA","NA","NA","adhesion G protein-coupled receptor E4, pseudogene [Source:HGNC Symbol;Acc:HGNC:19240]",{"v":0.903892470340259,"d":"0.90"},{"v":0.329484980427582,"d":"0.33"},{"v":2.74334954257172,"d":"2.74"},{"v":1.45593845419746,"d":"1.46"},{"v":0.0878305601555633,"d":"0.09"},{"v":0.61860994192239,"d":"0.62"},"up","no"]
["MSTRG.15163","TBL1X","ENST00000217964;ENST00000407597;ENST00000424279;MSTRG.15163.7;ENST00000497555;ENST00000380961;ENST00000422314;ENST00000441088;ENST00000452824","GO:0005634(nucleus);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0005515(protein binding);GO:0006508(proteolysis);GO:0045893(positive regulation of transcription, DNA-templated);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0003714(transcription corepressor activity);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0005654(nucleoplasm);GO:0007605(sensory perception of sound);GO:0008022(protein C-terminus binding);GO:0000118(histone deacetylase complex);GO:0005876(spindle microtubule);GO:0019904(protein domain specific binding);GO:0008134(transcription factor binding);GO:0042393(histone binding);GO:0044212(transcription regulatory region DNA binding);GO:0043161(proteasome-mediated ubiquitin-dependent protein catabolic process);GO:0008013(beta-catenin binding);GO:0060070(canonical Wnt signaling pathway);GO:0019216(regulation of lipid metabolic process);GO:0017053(transcriptional repressor complex);GO:0016575(histone deacetylation);GO:0016575(histone deacetylation)","04310(Wnt signaling pathway);04310(Wnt signaling pathway)","K04508","NA","transducin beta like 1X-linked [Source:HGNC Symbol;Acc:HGNC:11585]",{"v":14.6397988892852,"d":"14.64"},{"v":5.54755605464403,"d":"5.55"},{"v":2.63896367068338,"d":"2.64"},{"v":1.3999714899269,"d":"1.40"},{"v":0.0878401613906847,"d":"0.09"},{"v":0.61860994192239,"d":"0.62"},"up","no"]
["MSTRG.78","AL031282.1","ENST00000417099;ENST00000424604;ENST00000577672;ENST00000418950","NA","NA","NA","NA",null,{"v":2.55093990866256,"d":"2.55"},{"v":0.948052539688293,"d":"0.95"},{"v":2.69071575875033,"d":"2.69"},{"v":1.42798999592066,"d":"1.43"},{"v":0.0881132991854726,"d":"0.09"},{"v":0.619331701090701,"d":"0.62"},"up","no"]
["MSTRG.3634","APAF1","ENST00000551964;ENST00000357310;ENST00000359972;ENST00000546491;ENST00000547743;ENST00000555047;ENST00000550527;ENST00000547045","GO:0005737(cytoplasm);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0042981(regulation of apoptotic process);GO:0005515(protein binding);GO:0006915(apoptotic process);GO:0005576(extracellular region);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0043234(protein complex);GO:0043065(positive regulation of apoptotic process);GO:0043312(neutrophil degranulation);GO:0043531(ADP binding);GO:0097190(apoptotic signaling pathway);GO:0007399(nervous system development);GO:0034774(secretory granule lumen);GO:1904813(ficolin-1-rich granule lumen);GO:0097193(intrinsic apoptotic signaling pathway);GO:0008656(cysteine-type endopeptidase activator activity involved in apoptotic process);GO:0031072(heat shock protein binding);GO:0042802(identical protein binding);GO:0001666(response to hypoxia);GO:0001843(neural tube closure);GO:0006919(activation of cysteine-type endopeptidase activity involved in apoptotic process);GO:0007275(multicellular organism development);GO:0007420(brain development);GO:0007568(aging);GO:0007584(response to nutrient);GO:0008635(activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c);GO:0010659(cardiac muscle cell apoptotic process);GO:0030154(cell differentiation);GO:0030900(forebrain development);GO:0034349(glial cell apoptotic process);GO:0051260(protein homooligomerization);GO:0051402(neuron apoptotic process);GO:0070059(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress);GO:0071560(cellular response to transforming growth factor beta stimulus);GO:0072432(response to G1 DNA damage checkpoint signaling);GO:1902510(regulation of apoptotic DNA fragmentation);GO:2001235(positive regulation of apoptotic signaling pathway);GO:0005634(nucleus);GO:0043293(apoptosome);GO:0043293(apoptosome)","04210(Apoptosis);04215(Apoptosis - multiple species);04115(p53 signaling pathway);05200(Pathways in cancer);05222(Small cell lung cancer);05010(Alzheimer's disease);05012(Parkinson's disease);05014(Amyotrophic lateral sclerosis (ALS));05016(Huntington's disease);05134(Legionellosis);05152(Tuberculosis);05161(Hepatitis B);01524(Platinum drug resistance);01524(Platinum drug resistance)","K02084","NA","apoptotic peptidase activating factor 1 [Source:HGNC Symbol;Acc:HGNC:576]",{"v":10.983242128351,"d":"10.98"},{"v":4.16204101618614,"d":"4.16"},{"v":2.63890771033665,"d":"2.64"},{"v":1.39994089664075,"d":"1.40"},{"v":0.0881474245546589,"d":"0.09"},{"v":0.619331701090701,"d":"0.62"},"up","no"]
["ENSG00000170325","PRDM10","ENST00000360871;ENST00000358825;ENST00000528746;ENST00000423662;ENST00000531431;ENST00000533431","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0008168(methyltransferase activity);GO:0016740(transferase activity);GO:0032259(methylation);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0005515(protein binding)","NA","NA","NA","PR/SET domain 10 [Source:HGNC Symbol;Acc:HGNC:13995]",{"v":2.1200111705403,"d":"2.12"},{"v":0.799294137035919,"d":"0.80"},{"v":2.65235421143222,"d":"2.65"},{"v":1.40727345454284,"d":"1.41"},{"v":0.0881536011332971,"d":"0.09"},{"v":0.619331701090701,"d":"0.62"},"up","no"]
["ENSG00000143674","MAP3K21","ENST00000366624;ENST00000366622;ENST00000366623","GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0042803(protein homodimerization activity);GO:0005515(protein binding);GO:0004709(MAP kinase kinase kinase activity);GO:0000186(activation of MAPKK activity);GO:0005737(cytoplasm);GO:0005575(cellular_component);GO:0046777(protein autophosphorylation);GO:0007257(activation of JUN kinase activity);GO:0004706(JUN kinase kinase kinase activity);GO:0007256(activation of JNKK activity);GO:0005622(intracellular);GO:0000165(MAPK cascade);GO:0005634(nucleus);GO:0035556(intracellular signal transduction);GO:0004871(signal transducer activity);GO:0004871(signal transducer activity)","NA","NA","NA","mitogen-activated protein kinase kinase kinase 21 [Source:HGNC Symbol;Acc:HGNC:29798]",{"v":0.319167446563921,"d":"0.32"},{"v":0.115019150328449,"d":"0.12"},{"v":2.7749070102892,"d":"2.77"},{"v":1.47243942622223,"d":"1.47"},{"v":0.0882135877091588,"d":"0.09"},{"v":0.619331701090701,"d":"0.62"},"up","no"]
["ENSG00000081913","PHLPP1","ENST00000262719;ENST00000588953;ENST00000591106;ENST00000588452;ENST00000487409","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0046872(metal ion binding);GO:0016787(hydrolase activity);GO:0003824(catalytic activity);GO:0005886(plasma membrane);GO:0004721(phosphoprotein phosphatase activity);GO:0005515(protein binding);GO:0006915(apoptotic process);GO:0006470(protein dephosphorylation);GO:0005829(cytosol);GO:0042981(regulation of apoptotic process);GO:0031965(nuclear membrane);GO:0051898(negative regulation of protein kinase B signaling);GO:1900744(regulation of p38MAPK cascade);GO:0004722(protein serine/threonine phosphatase activity);GO:0002667(regulation of T cell anergy);GO:0009649(entrainment of circadian clock);GO:0043408(regulation of MAPK cascade);GO:0046328(regulation of JNK cascade);GO:0090036(regulation of protein kinase C signaling);GO:0090036(regulation of protein kinase C signaling)","04151(PI3K-Akt signaling pathway);04151(PI3K-Akt signaling pathway)","K16340","EC:3.1.3.16","PH domain and leucine rich repeat protein phosphatase 1 [Source:HGNC Symbol;Acc:HGNC:20610]",{"v":1.13897800809451,"d":"1.14"},{"v":0.426134868737694,"d":"0.43"},{"v":2.67281110196031,"d":"2.67"},{"v":1.41835788026899,"d":"1.42"},{"v":0.088231219319117,"d":"0.09"},{"v":0.619331701090701,"d":"0.62"},"up","no"]
["MSTRG.10959","NPRL2","ENST00000232501;ENST00000451194;ENST00000418825;ENST00000469839;ENST00000480296;ENST00000476064;ENST00000493907;ENST00000492805;ENST00000467294;ENST00000433999;ENST00000493465;ENST00000433381;ENST00000487632;ENST00000461020;ENST00000448302;ENST00000429366;ENST00000479512","GO:0016020(membrane);GO:0006468(protein phosphorylation);GO:0005765(lysosomal membrane);GO:0043547(positive regulation of GTPase activity);GO:0005096(GTPase activator activity);GO:0005764(lysosome);GO:0005515(protein binding);GO:0006995(cellular response to nitrogen starvation);GO:0004672(protein kinase activity);GO:2000785(regulation of autophagosome assembly);GO:0032007(negative regulation of TOR signaling);GO:0034198(cellular response to amino acid starvation);GO:1990130(GATOR1 complex);GO:0033673(negative regulation of kinase activity);GO:0010508(positive regulation of autophagy);GO:0010508(positive regulation of autophagy)","04150(mTOR signaling pathway);04150(mTOR signaling pathway)","K20405","NA","NPR2 like, GATOR1 complex subunit [Source:HGNC Symbol;Acc:HGNC:24969]",{"v":3.79623246396519,"d":"3.80"},{"v":6.91720638781615,"d":"6.92"},{"v":0.548810061624272,"d":"0.55"},{"v":-0.865621163445193,"d":"-0.87"},{"v":0.0883697413090311,"d":"0.09"},{"v":0.619331701090701,"d":"0.62"},"down","no"]
["ENSG00000110079","MS4A4A","ENST00000337908;ENST00000532114;ENST00000527056;ENST00000343968;ENST00000529950;ENST00000529991","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016021(integral component of membrane)","NA","NA","NA","membrane spanning 4-domains A4A [Source:HGNC Symbol;Acc:HGNC:13371]",{"v":0.41561743261563,"d":"0.42"},{"v":0.781896369218501,"d":"0.78"},{"v":0.531550534031813,"d":"0.53"},{"v":-0.911721240889275,"d":"-0.91"},{"v":0.0883705424837047,"d":"0.09"},{"v":0.619331701090701,"d":"0.62"},"down","no"]
["MSTRG.6291","SMYD4","ENST00000305513;ENST00000573937;ENST00000476292;ENST00000491788;ENST00000576633","GO:0046872(metal ion binding);GO:0008168(methyltransferase activity);GO:0016740(transferase activity);GO:0032259(methylation);GO:0032259(methylation)","NA","NA","NA","SET and MYND domain containing 4 [Source:HGNC Symbol;Acc:HGNC:21067]",{"v":1.73885133407112,"d":"1.74"},{"v":0.652332657813192,"d":"0.65"},{"v":2.66558988461539,"d":"2.67"},{"v":1.41445483108512,"d":"1.41"},{"v":0.0883812297516597,"d":"0.09"},{"v":0.619331701090701,"d":"0.62"},"up","no"]
["MSTRG.14019","BRAF","ENST00000288602;ENST00000496384;ENST00000469930;ENST00000497784;ENST00000479537","GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0010628(positive regulation of gene expression);GO:0070374(positive regulation of ERK1 and ERK2 cascade);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0043231(intracellular membrane-bounded organelle);GO:0046872(metal ion binding);GO:0005829(cytosol);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0035556(intracellular signal transduction);GO:0007165(signal transduction);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0005057(signal transducer activity, downstream of receptor);GO:0000186(activation of MAPKK activity);GO:0042802(identical protein binding);GO:0005622(intracellular);GO:0033138(positive regulation of peptidyl-serine phosphorylation);GO:0000165(MAPK cascade);GO:0030154(cell differentiation);GO:0043066(negative regulation of apoptotic process);GO:0009887(animal organ morphogenesis);GO:0005509(calcium ion binding);GO:0004709(MAP kinase kinase kinase activity);GO:0031434(mitogen-activated protein kinase kinase binding);GO:0009968(negative regulation of signal transduction);GO:0046982(protein heterodimerization activity);GO:0002318(myeloid progenitor cell differentiation);GO:0008542(visual learning);GO:0010764(negative regulation of fibroblast migration);GO:0015758(glucose transport);GO:0030878(thyroid gland development);GO:0035019(somatic stem cell population maintenance);GO:0035690(cellular response to drug);GO:0042127(regulation of cell proliferation);GO:0043367(CD4-positive, alpha-beta T cell differentiation);GO:0043368(positive T cell selection);GO:0043369(CD4-positive or CD8-positive, alpha-beta T cell lineage commitment);GO:0043434(response to peptide hormone);GO:0043524(negative regulation of neuron apoptotic process);GO:0045580(regulation of T cell differentiation);GO:0046632(alpha-beta T cell differentiation);GO:0048538(thymus development);GO:0048679(regulation of axon regeneration);GO:0048680(positive regulation of axon regeneration);GO:0050772(positive regulation of axonogenesis);GO:0050852(T cell receptor signaling pathway);GO:0051291(protein heterooligomerization);GO:0051496(positive regulation of stress fiber assembly);GO:0051591(response to cAMP);GO:0060291(long-term synaptic potentiation);GO:0060323(head morphogenesis);GO:0060324(face development);GO:0071277(cellular response to calcium ion);GO:0090150(establishment of protein localization to membrane);GO:1900026(positive regulation of substrate adhesion-dependent cell spreading);GO:1990090(cellular response to nerve growth factor stimulus);GO:2000301(negative regulation of synaptic vesicle exocytosis);GO:2000352(negative regulation of endothelial cell apoptotic process);GO:0005739(mitochondrion);GO:0043005(neuron projection);GO:0044297(cell body);GO:0044297(cell body)","04015(Rap1 signaling pathway);04010(MAPK signaling pathway);04012(ErbB signaling pathway);04068(FoxO signaling pathway);04024(cAMP signaling pathway);04150(mTOR signaling pathway);04510(Focal adhesion);04810(Regulation of actin cytoskeleton);04650(Natural killer cell mediated cytotoxicity);04062(Chemokine signaling pathway);04910(Insulin signaling pathway);04914(Progesterone-mediated oocyte maturation);04270(Vascular smooth muscle contraction);04726(Serotonergic synapse);04720(Long-term potentiation);04730(Long-term depression);04722(Neurotrophin signaling pathway);05200(Pathways in cancer);05205(Proteoglycans in cancer);05210(Colorectal cancer);05212(Pancreatic cancer);05225(Hepatocellular carcinoma);05226(Gastric cancer);05214(Glioma);05216(Thyroid cancer);05221(Acute myeloid leukemia);05220(Chronic myeloid leukemia);05218(Melanoma);05211(Renal cell carcinoma);05219(Bladder cancer);05215(Prostate cancer);05213(Endometrial cancer);05224(Breast cancer);05223(Non-small cell lung cancer);05034(Alcoholism);05160(Hepatitis C);01521(EGFR tyrosine kinase inhibitor resistance);01522(Endocrine resistance);01522(Endocrine resistance)","K04365","EC:2.7.11.1","B-Raf proto-oncogene, serine/threonine kinase [Source:HGNC Symbol;Acc:HGNC:1097]",{"v":4.55101160192678,"d":"4.55"},{"v":1.72270370500963,"d":"1.72"},{"v":2.64178430027893,"d":"2.64"},{"v":1.40151267641754,"d":"1.40"},{"v":0.0884656116458547,"d":"0.09"},{"v":0.619331701090701,"d":"0.62"},"up","no"]
["MSTRG.13312","HECA","ENST00000367658","GO:0016020(membrane);GO:0007275(multicellular organism development);GO:0003674(molecular_function);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0045930(negative regulation of mitotic cell cycle);GO:0030323(respiratory tube development)","NA","NA","NA","hdc homolog, cell cycle regulator [Source:HGNC Symbol;Acc:HGNC:21041]",{"v":22.173223,"d":"22.17"},{"v":8.419089,"d":"8.42"},{"v":2.63368435706048,"d":"2.63"},{"v":1.39708245121686,"d":"1.40"},{"v":0.0884768580357498,"d":"0.09"},{"v":0.619331701090701,"d":"0.62"},"up","no"]
["ENSG00000134291","TMEM106C","ENST00000550552;ENST00000552561;ENST00000256686;ENST00000550161;ENST00000449758;ENST00000551705;ENST00000552546;ENST00000549288;ENST00000546749;ENST00000551305;ENST00000429772;ENST00000548965;ENST00000547136;ENST00000547682;ENST00000549287;ENST00000615597;ENST00000553217;ENST00000552187;ENST00000550146","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005515(protein binding);GO:0003674(molecular_function);GO:0008150(biological_process);GO:0005575(cellular_component);GO:0005575(cellular_component)","NA","NA","NA","transmembrane protein 106C [Source:HGNC Symbol;Acc:HGNC:28775]",{"v":1.65051349899281,"d":"1.65"},{"v":3.01664219683453,"d":"3.02"},{"v":0.547135984746468,"d":"0.55"},{"v":-0.870028651014735,"d":"-0.87"},{"v":0.0885292881951747,"d":"0.09"},{"v":0.619331701090701,"d":"0.62"},"down","no"]
["MSTRG.14836","SEMA4D","MSTRG.14836.15;MSTRG.14836.11;MSTRG.14836.2;ENST00000438547;MSTRG.14836.19;ENST00000486935;ENST00000420101;ENST00000455551;ENST00000429836;ENST00000474258;ENST00000540475;MSTRG.14836.13;ENST00000544513;ENST00000492386;ENST00000540183;MSTRG.14836.18;ENST00000420670;ENST00000464051;ENST00000420681;ENST00000469653;ENST00000537934;ENST00000482128;ENST00000422704;ENST00000433650;ENST00000356444;ENST00000450295;ENST00000475255","GO:0005615(extracellular space);GO:0030335(positive regulation of cell migration);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005886(plasma membrane);GO:0007275(multicellular organism development);GO:0007399(nervous system development);GO:0030154(cell differentiation);GO:0005887(integral component of plasma membrane);GO:0005515(protein binding);GO:0001934(positive regulation of protein phosphorylation);GO:0043547(positive regulation of GTPase activity);GO:0005102(receptor binding);GO:0008360(regulation of cell shape);GO:0050731(positive regulation of peptidyl-tyrosine phosphorylation);GO:0006955(immune response);GO:0007155(cell adhesion);GO:0004888(transmembrane signaling receptor activity);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0043066(negative regulation of apoptotic process);GO:0007162(negative regulation of cell adhesion);GO:0071526(semaphorin-plexin signaling pathway);GO:0050919(negative chemotaxis);GO:0030215(semaphorin receptor binding);GO:0014068(positive regulation of phosphatidylinositol 3-kinase signaling);GO:0043931(ossification involved in bone maturation);GO:1900220(semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis);GO:0048814(regulation of dendrite morphogenesis);GO:0045668(negative regulation of osteoblast differentiation);GO:0050732(negative regulation of peptidyl-tyrosine phosphorylation);GO:0010693(negative regulation of alkaline phosphatase activity);GO:0031344(regulation of cell projection organization);GO:0004872(receptor activity);GO:0048672(positive regulation of collateral sprouting);GO:0050772(positive regulation of axonogenesis);GO:0070486(leukocyte aggregation);GO:0070486(leukocyte aggregation)","04360(Axon guidance);04360(Axon guidance)","K06521","NA","semaphorin 4D [Source:HGNC Symbol;Acc:HGNC:10732]",{"v":15.7436992557138,"d":"15.74"},{"v":5.98163993956235,"d":"5.98"},{"v":2.63200383419696,"d":"2.63"},{"v":1.3961615907346,"d":"1.40"},{"v":0.0888638238534778,"d":"0.09"},{"v":0.620740386337155,"d":"0.62"},"up","no"]
["MSTRG.8841","HK2","ENST00000290573;ENST00000409174;ENST00000472302","GO:0016020(membrane);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0006096(glycolytic process);GO:0004396(hexokinase activity);GO:0005536(glucose binding);GO:0016773(phosphotransferase activity, alcohol group as acceptor);GO:0001678(cellular glucose homeostasis);GO:0005975(carbohydrate metabolic process);GO:0046835(carbohydrate phosphorylation);GO:0051156(glucose 6-phosphate metabolic process);GO:0005739(mitochondrion);GO:0005515(protein binding);GO:0003824(catalytic activity);GO:0008152(metabolic process);GO:0005741(mitochondrial outer membrane);GO:0005829(cytosol);GO:0061621(canonical glycolysis);GO:0004340(glucokinase activity);GO:0008865(fructokinase activity);GO:0019158(mannokinase activity);GO:0019318(hexose metabolic process);GO:0072655(establishment of protein localization to mitochondrion);GO:0072656(maintenance of protein location in mitochondrion);GO:0002931(response to ischemia);GO:0006006(glucose metabolic process);GO:0007595(lactation);GO:0008637(apoptotic mitochondrial changes);GO:0035795(negative regulation of mitochondrial membrane permeability);GO:0046324(regulation of glucose import);GO:1904925(positive regulation of mitophagy in response to mitochondrial depolarization);GO:1990830(cellular response to leukemia inhibitory factor);GO:2000378(negative regulation of reactive oxygen species metabolic process);GO:0005623(cell);GO:0005623(cell)","00010(Glycolysis / Gluconeogenesis);00051(Fructose and mannose metabolism);00052(Galactose metabolism);00500(Starch and sucrose metabolism);00520(Amino sugar and nucleotide sugar metabolism);00524(Neomycin, kanamycin and gentamicin biosynthesis);04066(HIF-1 signaling pathway);04910(Insulin signaling pathway);04973(Carbohydrate digestion and absorption);05230(Central carbon metabolism in cancer);04930(Type II diabetes mellitus);04930(Type II diabetes mellitus)","K00844","EC:2.7.1.1","hexokinase 2 [Source:HGNC Symbol;Acc:HGNC:4923]",{"v":9.0597139676781,"d":"9.06"},{"v":3.43918680474934,"d":"3.44"},{"v":2.63426050459577,"d":"2.63"},{"v":1.3973980221718,"d":"1.40"},{"v":0.0888906246087598,"d":"0.09"},{"v":0.620740386337155,"d":"0.62"},"up","no"]
["ENSG00000070047","PHRF1","ENST00000413872;ENST00000416188;ENST00000264555;ENST00000533464;ENST00000534320;ENST00000532550","GO:0016020(membrane);GO:0046872(metal ion binding);GO:0070063(RNA polymerase binding);GO:0019904(protein domain specific binding);GO:0006366(transcription from RNA polymerase II promoter);GO:0006397(mRNA processing);GO:0006397(mRNA processing)","NA","NA","NA","PHD and ring finger domains 1 [Source:HGNC Symbol;Acc:HGNC:24351]",{"v":7.21297637944184,"d":"7.21"},{"v":2.73481930039868,"d":"2.73"},{"v":2.63745995151868,"d":"2.64"},{"v":1.39914918739932,"d":"1.40"},{"v":0.0888991046432643,"d":"0.09"},{"v":0.620740386337155,"d":"0.62"},"up","no"]
["ENSG00000100068","LRP5L","ENST00000444995;ENST00000610821;ENST00000402785;ENST00000484509;ENST00000467672;ENST00000402859","NA","NA","NA","NA","LDL receptor related protein 5 like [Source:HGNC Symbol;Acc:HGNC:25323]",{"v":0.493615958946213,"d":"0.49"},{"v":0.170725018221734,"d":"0.17"},{"v":2.89129246602343,"d":"2.89"},{"v":1.53171455068299,"d":"1.53"},{"v":0.0889949182588867,"d":"0.09"},{"v":0.620740386337155,"d":"0.62"},"up","no"]
["MSTRG.15327","PAGE2B","MSTRG.15327.1;ENST00000374971;ENST00000374974","NA","NA","NA","NA","PAGE family member 2B [Source:HGNC Symbol;Acc:HGNC:31805]",{"v":1.99823146236559,"d":"2.00"},{"v":3.7511205437788,"d":"3.75"},{"v":0.532702545557924,"d":"0.53"},{"v":-0.908597919948468,"d":"-0.91"},{"v":0.0889979112418293,"d":"0.09"},{"v":0.620740386337155,"d":"0.62"},"down","no"]
["MSTRG.15037","FNBP1","ENST00000443566;ENST00000462766;ENST00000482107;ENST00000491905;ENST00000355681;ENST00000449089;ENST00000420781;ENST00000446176","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0006897(endocytosis);GO:0005886(plasma membrane);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0031410(cytoplasmic vesicle);GO:0005905(clathrin-coated pit);GO:0005764(lysosome);GO:0042802(identical protein binding);GO:0008289(lipid binding);GO:0005829(cytosol);GO:0061024(membrane organization);GO:0005938(cell cortex);GO:0005938(cell cortex)","NA","NA","NA","formin binding protein 1 [Source:HGNC Symbol;Acc:HGNC:17069]",{"v":26.1592531027273,"d":"26.16"},{"v":9.94948544909091,"d":"9.95"},{"v":2.6292066294863,"d":"2.63"},{"v":1.39462752789012,"d":"1.39"},{"v":0.089142200349078,"d":"0.09"},{"v":0.621373573021515,"d":"0.62"},"up","no"]
["MSTRG.10724","UBE2E2","ENST00000425792;ENST00000396703;ENST00000452894","GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0016740(transferase activity);GO:0016567(protein ubiquitination);GO:0005515(protein binding);GO:0061631(ubiquitin conjugating enzyme activity);GO:0004842(ubiquitin-protein transferase activity);GO:0070534(protein K63-linked ubiquitination);GO:0070936(protein K48-linked ubiquitination);GO:0070979(protein K11-linked ubiquitination);GO:0006974(cellular response to DNA damage stimulus);GO:0032020(ISG15-protein conjugation);GO:0042296(ISG15 transferase activity);GO:1900087(positive regulation of G1/S transition of mitotic cell cycle);GO:1900087(positive regulation of G1/S transition of mitotic cell cycle)","04120(Ubiquitin mediated proteolysis);04120(Ubiquitin mediated proteolysis)","K20217","EC:2.3.2.23","ubiquitin conjugating enzyme E2 E2 [Source:HGNC Symbol;Acc:HGNC:12478]",{"v":0.955612354306659,"d":"0.96"},{"v":1.75197534392181,"d":"1.75"},{"v":0.545448517652945,"d":"0.55"},{"v":-0.874485061183277,"d":"-0.87"},{"v":0.0892786617299802,"d":"0.09"},{"v":0.621951468908374,"d":"0.62"},"down","no"]
["MSTRG.7030","SPAG9","ENST00000357122;ENST00000262013;ENST00000513906;ENST00000511312;ENST00000505279;ENST00000506500;ENST00000509724;ENST00000513547;ENST00000510283;ENST00000511987;ENST00000514613;ENST00000511795;ENST00000513827;ENST00000505173;ENST00000506483;ENST00000515685;ENST00000514205","GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005515(protein binding);GO:0048471(perinuclear region of cytoplasm);GO:0005815(microtubule organizing center);GO:0031410(cytoplasmic vesicle);GO:0070062(extracellular exosome);GO:0030335(positive regulation of cell migration);GO:0001669(acrosomal vesicle);GO:0016021(integral component of membrane);GO:0007283(spermatogenesis);GO:0007257(activation of JUN kinase activity);GO:0005078(MAP-kinase scaffold activity);GO:0008432(JUN kinase binding);GO:0019894(kinesin binding);GO:0030159(receptor signaling complex scaffold activity);GO:0048273(mitogen-activated protein kinase p38 binding);GO:0000187(activation of MAPK activity);GO:0042147(retrograde transport, endosome to Golgi);GO:0043410(positive regulation of MAPK cascade);GO:0045666(positive regulation of neuron differentiation);GO:0051146(striated muscle cell differentiation);GO:0051149(positive regulation of muscle cell differentiation);GO:0051260(protein homooligomerization);GO:0090074(negative regulation of protein homodimerization activity);GO:0016020(membrane);GO:0016020(membrane)","NA","NA","NA","sperm associated antigen 9 [Source:HGNC Symbol;Acc:HGNC:14524]",{"v":5.6425445533729,"d":"5.64"},{"v":2.14041792159157,"d":"2.14"},{"v":2.63618823990094,"d":"2.64"},{"v":1.3984533912395,"d":"1.40"},{"v":0.0893655781990738,"d":"0.09"},{"v":0.622183728792472,"d":"0.62"},"up","no"]
["MSTRG.14891","NIPSNAP3A","ENST00000374767;ENST00000471001","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005515(protein binding);GO:0005739(mitochondrion);GO:0005739(mitochondrion)","NA","NA","NA","nipsnap homolog 3A [Source:HGNC Symbol;Acc:HGNC:23619]",{"v":1.9842751729207,"d":"1.98"},{"v":3.62722782978723,"d":"3.63"},{"v":0.547050052005445,"d":"0.55"},{"v":-0.870255257342024,"d":"-0.87"},{"v":0.0894962353098016,"d":"0.09"},{"v":0.622720060307206,"d":"0.62"},"down","no"]
["ENSG00000198598","MMP17","ENST00000360564;ENST00000537848;ENST00000535004;ENST00000542648;ENST00000542142;ENST00000535271;ENST00000534865;ENST00000545790;ENST00000535291","GO:0016020(membrane);GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0016787(hydrolase activity);GO:0005886(plasma membrane);GO:0043085(positive regulation of catalytic activity);GO:0008233(peptidase activity);GO:0006508(proteolysis);GO:0005576(extracellular region);GO:0005578(proteinaceous extracellular matrix);GO:0004222(metalloendopeptidase activity);GO:0008237(metallopeptidase activity);GO:0031012(extracellular matrix);GO:0031225(anchored component of membrane);GO:0005887(integral component of plasma membrane);GO:0008047(enzyme activator activity);GO:0070006(metalloaminopeptidase activity);GO:0001822(kidney development);GO:0042756(drinking behavior);GO:0042756(drinking behavior)","NA","NA","NA","matrix metallopeptidase 17 [Source:HGNC Symbol;Acc:HGNC:7163]",{"v":1.08381934649013,"d":"1.08"},{"v":0.400196935548339,"d":"0.40"},{"v":2.70821500670691,"d":"2.71"},{"v":1.4373422798274,"d":"1.44"},{"v":0.089658313042788,"d":"0.09"},{"v":0.623130804458991,"d":"0.62"},"up","no"]
["MSTRG.950","ZNF687","ENST00000336715;ENST00000443959;ENST00000436614;ENST00000324048;ENST00000459919;ENST00000426871","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0005515(protein binding)","NA","NA","NA","zinc finger protein 687 [Source:HGNC Symbol;Acc:HGNC:29277]",{"v":5.96744965569381,"d":"5.97"},{"v":2.26537081871161,"d":"2.27"},{"v":2.63420434588616,"d":"2.63"},{"v":1.39736726562538,"d":"1.40"},{"v":0.0896625828167549,"d":"0.09"},{"v":0.623130804458991,"d":"0.62"},"up","no"]
["MSTRG.3501","TSPAN31","ENST00000257910;ENST00000550791;ENST00000552816;ENST00000553089;ENST00000547311;ENST00000553221;ENST00000547992;ENST00000547472;ENST00000549052;ENST00000546922;ENST00000546993","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0007166(cell surface receptor signaling pathway);GO:0005887(integral component of plasma membrane);GO:0008284(positive regulation of cell proliferation);GO:0008284(positive regulation of cell proliferation)","NA","NA","NA","tetraspanin 31 [Source:HGNC Symbol;Acc:HGNC:10539]",{"v":1.05825623324048,"d":"1.06"},{"v":1.93377979257196,"d":"1.93"},{"v":0.547247539407256,"d":"0.55"},{"v":-0.869734532265845,"d":"-0.87"},{"v":0.0897879044041542,"d":"0.09"},{"v":0.623232610772391,"d":"0.62"},"down","no"]
["ENSG00000163599","CTLA4","ENST00000302823;ENST00000295854","GO:0048471(perinuclear region of cytoplasm);GO:0045590(negative regulation of regulatory T cell differentiation);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0006974(cellular response to DNA damage stimulus);GO:0006955(immune response);GO:0002376(immune system process);GO:0002250(adaptive immune response);GO:0005887(integral component of plasma membrane);GO:0043065(positive regulation of apoptotic process);GO:0009897(external side of plasma membrane);GO:0050853(B cell receptor signaling pathway);GO:0031295(T cell costimulation);GO:0005794(Golgi apparatus);GO:0030889(negative regulation of B cell proliferation);GO:0045589(regulation of regulatory T cell differentiation);GO:0098636(protein complex involved in cell adhesion);GO:0042130(negative regulation of T cell proliferation);GO:0050777(negative regulation of immune response);GO:0045334(clathrin-coated endocytic vesicle);GO:0045334(clathrin-coated endocytic vesicle)","04514(Cell adhesion molecules (CAMs));04660(T cell receptor signaling pathway);05323(Rheumatoid arthritis);05320(Autoimmune thyroid disease);05320(Autoimmune thyroid disease)","K06538","NA","cytotoxic T-lymphocyte associated protein 4 [Source:HGNC Symbol;Acc:HGNC:2505]",{"v":0.473252767924528,"d":"0.47"},{"v":0.910701079245283,"d":"0.91"},{"v":0.519657633783329,"d":"0.52"},{"v":-0.944366649932263,"d":"-0.94"},{"v":0.0898632852387779,"d":"0.09"},{"v":0.623232610772391,"d":"0.62"},"down","no"]
["MSTRG.2454","TMEM258","ENST00000537328;ENST00000257262;ENST00000535042;ENST00000543510;ENST00000541893;ENST00000545210;ENST00000540434","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005783(endoplasmic reticulum);GO:0006487(protein N-linked glycosylation);GO:0006486(protein glycosylation);GO:0034998(oligosaccharyltransferase I complex);GO:0034998(oligosaccharyltransferase I complex)","NA","NA","NA","transmembrane protein 258 [Source:HGNC Symbol;Acc:HGNC:1164]",{"v":2.39216636734029,"d":"2.39"},{"v":4.35574910919166,"d":"4.36"},{"v":0.549197464631802,"d":"0.55"},{"v":-0.864603129583647,"d":"-0.86"},{"v":0.0898840605405907,"d":"0.09"},{"v":0.623232610772391,"d":"0.62"},"down","no"]
["ENSG00000154640","BTG3","ENST00000348354;ENST00000457956;ENST00000339775;ENST00000496601;ENST00000464058","GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0008285(negative regulation of cell proliferation);GO:0045930(negative regulation of mitotic cell cycle);GO:0045930(negative regulation of mitotic cell cycle)","03018(RNA degradation);03018(RNA degradation)","K14443","NA","BTG anti-proliferation factor 3 [Source:HGNC Symbol;Acc:HGNC:1132]",{"v":0.893415111882047,"d":"0.89"},{"v":1.65252765741544,"d":"1.65"},{"v":0.540635497308016,"d":"0.54"},{"v":-0.887271854733293,"d":"-0.89"},{"v":0.0899540284145977,"d":"0.09"},{"v":0.623232610772391,"d":"0.62"},"down","no"]
["MSTRG.14786","DCAF10","ENST00000377724;ENST00000242323;ENST00000478453;ENST00000461549;ENST00000483167","GO:0016567(protein ubiquitination);GO:0005654(nucleoplasm);GO:0043687(post-translational protein modification);GO:0080008(Cul4-RING E3 ubiquitin ligase complex);GO:0080008(Cul4-RING E3 ubiquitin ligase complex)","NA","NA","NA","DDB1 and CUL4 associated factor 10 [Source:HGNC Symbol;Acc:HGNC:23686]",{"v":0.975139006594442,"d":"0.98"},{"v":0.365899899199246,"d":"0.37"},{"v":2.6650431135086,"d":"2.67"},{"v":1.41415887224972,"d":"1.41"},{"v":0.0900021572973792,"d":"0.09"},{"v":0.623232610772391,"d":"0.62"},"up","no"]
["MSTRG.13073","POLH","ENST00000372236","GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0016740(transferase activity);GO:0003677(DNA binding);GO:0003684(damaged DNA binding);GO:0006281(DNA repair);GO:0005515(protein binding);GO:0006974(cellular response to DNA damage stimulus);GO:0016779(nucleotidyltransferase activity);GO:0003887(DNA-directed DNA polymerase activity);GO:0006260(DNA replication);GO:0071897(DNA biosynthetic process);GO:0006290(pyrimidine dimer repair);GO:0006301(postreplication repair);GO:0071494(cellular response to UV-C);GO:0019985(translesion synthesis);GO:0070987(error-free translesion synthesis);GO:0010225(response to UV-C);GO:0000731(DNA synthesis involved in DNA repair);GO:0006282(regulation of DNA repair)","03460(Fanconi anemia pathway);01524(Platinum drug resistance)","K03509","EC:2.7.7.7","DNA polymerase eta [Source:HGNC Symbol;Acc:HGNC:9181]",{"v":3.240711,"d":"3.24"},{"v":1.224573,"d":"1.22"},{"v":2.6464008270638,"d":"2.65"},{"v":1.40403159049874,"d":"1.40"},{"v":0.0900239801107833,"d":"0.09"},{"v":0.623232610772391,"d":"0.62"},"up","no"]
["MSTRG.7935","USE1","ENST00000263897;ENST00000601592;ENST00000593597;ENST00000594724;ENST00000445667;ENST00000594399;ENST00000601662;ENST00000600970;ENST00000595101","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0015031(protein transport);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005515(protein binding);GO:0016192(vesicle-mediated transport);GO:0006890(retrograde vesicle-mediated transport, Golgi to ER);GO:0007041(lysosomal transport);GO:0030163(protein catabolic process);GO:0032940(secretion by cell);GO:0032940(secretion by cell)","04130(SNARE interactions in vesicular transport);04130(SNARE interactions in vesicular transport)","K08507","NA","unconventional SNARE in the ER 1 [Source:HGNC Symbol;Acc:HGNC:30882]",{"v":1.47816732044426,"d":"1.48"},{"v":2.71378047017688,"d":"2.71"},{"v":0.544689350037188,"d":"0.54"},{"v":-0.876494435527512,"d":"-0.88"},{"v":0.0901782649631361,"d":"0.09"},{"v":0.623232610772391,"d":"0.62"},"down","no"]
["MSTRG.8404","CNOT3","ENST00000221232;ENST00000471126;ENST00000358389;ENST00000618939;ENST00000457463;ENST00000613073;ENST00000496327;ENST00000440571;ENST00000617930","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0005515(protein binding);GO:0007275(multicellular organism development);GO:0030015(CCR4-NOT core complex);GO:0031047(gene silencing by RNA);GO:0000932(P-body);GO:0006977(DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest);GO:0005829(cytosol);GO:0000289(nuclear-transcribed mRNA poly(A) tail shortening);GO:0006417(regulation of translation);GO:2000036(regulation of stem cell population maintenance);GO:0030014(CCR4-NOT complex);GO:0000288(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay);GO:0017148(negative regulation of translation);GO:0001829(trophectodermal cell differentiation);GO:0001829(trophectodermal cell differentiation)","03018(RNA degradation);03018(RNA degradation)","K12580","NA","CCR4-NOT transcription complex subunit 3 [Source:HGNC Symbol;Acc:HGNC:7879]",{"v":4.88215971464949,"d":"4.88"},{"v":1.85121288825644,"d":"1.85"},{"v":2.63727621259581,"d":"2.64"},{"v":1.39904867839766,"d":"1.40"},{"v":0.0902035812209871,"d":"0.09"},{"v":0.623232610772391,"d":"0.62"},"up","no"]
["ENSG00000125962","ARMCX5","ENST00000477663;ENST00000479502;ENST00000372742;ENST00000473968;ENST00000246174;ENST00000604957","GO:0005515(protein binding);GO:0005515(protein binding)","NA","NA","NA","armadillo repeat containing, X-linked 5 [Source:HGNC Symbol;Acc:HGNC:25772]",{"v":0.209731002443494,"d":"0.21"},{"v":0.391593279780086,"d":"0.39"},{"v":0.53558376323842,"d":"0.54"},{"v":-0.9008158703164,"d":"-0.90"},{"v":0.0902838428217927,"d":"0.09"},{"v":0.623232610772391,"d":"0.62"},"down","no"]
["MSTRG.12295","AFF4","ENST00000265343;MSTRG.12295.2;ENST00000378595;ENST00000465484;ENST00000491831;ENST00000378593;ENST00000421773","GO:0005634(nucleus);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0001650(fibrillar center);GO:0005515(protein binding);GO:0005654(nucleoplasm);GO:0006366(transcription from RNA polymerase II promoter);GO:0006368(transcription elongation from RNA polymerase II promoter);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0008023(transcription elongation factor complex);GO:0035327(transcriptionally active chromatin);GO:0007286(spermatid development);GO:0007286(spermatid development)","NA","NA","NA","AF4/FMR2 family member 4 [Source:HGNC Symbol;Acc:HGNC:17869]",{"v":7.37071746826168,"d":"7.37"},{"v":2.80918242473735,"d":"2.81"},{"v":2.62379452589335,"d":"2.62"},{"v":1.39165474431513,"d":"1.39"},{"v":0.0902912762123481,"d":"0.09"},{"v":0.623232610772391,"d":"0.62"},"up","no"]
["ENSG00000167528","ZNF641","ENST00000547026;ENST00000544117;ENST00000548932;ENST00000546874;ENST00000550342;ENST00000448928;ENST00000301042;ENST00000549512","GO:0005634(nucleus);GO:0003676(nucleic acid binding);GO:0046872(metal ion binding);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0005622(intracellular);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0000981(RNA polymerase II transcription factor activity, sequence-specific DNA binding);GO:0000981(RNA polymerase II transcription factor activity, sequence-specific DNA binding)","NA","NA","NA","zinc finger protein 641 [Source:HGNC Symbol;Acc:HGNC:31834]",{"v":0.992830683738494,"d":"0.99"},{"v":1.80775786641492,"d":"1.81"},{"v":0.549205566842555,"d":"0.55"},{"v":-0.864581845921933,"d":"-0.86"},{"v":0.0903028453270158,"d":"0.09"},{"v":0.623232610772391,"d":"0.62"},"down","no"]
["MSTRG.255","SRRM1","ENST00000479034;ENST00000323848;ENST00000596378;ENST00000600523;ENST00000470243;ENST00000466910;ENST00000485441;ENST00000485541;ENST00000490543;ENST00000474843;ENST00000461768;ENST00000494934;ENST00000488317;ENST00000468822;ENST00000489130;ENST00000495561;ENST00000462710;ENST00000374389","GO:0006397(mRNA processing);GO:0003723(RNA binding);GO:0008380(RNA splicing);GO:0005634(nucleus);GO:0016607(nuclear speck);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0005681(spliceosomal complex);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0000398(mRNA splicing, via spliceosome);GO:0006369(termination of RNA polymerase II transcription);GO:0006405(RNA export from nucleus);GO:0031124(mRNA 3'-end processing);GO:0016363(nuclear matrix);GO:0000375(RNA splicing, via transesterification reactions);GO:0006406(mRNA export from nucleus);GO:0071013(catalytic step 2 spliceosome);GO:0071013(catalytic step 2 spliceosome)","03013(RNA transport);03015(mRNA surveillance pathway);03015(mRNA surveillance pathway)","K13171","NA","serine and arginine repetitive matrix 1 [Source:HGNC Symbol;Acc:HGNC:16638]",{"v":6.81975712659158,"d":"6.82"},{"v":2.59341660063663,"d":"2.59"},{"v":2.62964196531998,"d":"2.63"},{"v":1.39486638506141,"d":"1.39"},{"v":0.0903212334392434,"d":"0.09"},{"v":0.623232610772391,"d":"0.62"},"up","no"]
["ENSG00000186104","CYP2R1","ENST00000532378;ENST00000526489;ENST00000532641;ENST00000534686;ENST00000530609;ENST00000532805;ENST00000334636;ENST00000525015;ENST00000529043","GO:0016020(membrane);GO:0046872(metal ion binding);GO:0004497(monooxygenase activity);GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005506(iron ion binding);GO:0016705(oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen);GO:0020037(heme binding);GO:0008395(steroid hydroxylase activity);GO:0043231(intracellular membrane-bounded organelle);GO:0031090(organelle membrane);GO:0006766(vitamin metabolic process);GO:0042359(vitamin D metabolic process);GO:0036378(calcitriol biosynthetic process from calciol);GO:0030343(vitamin D3 25-hydroxylase activity);GO:0010038(response to metal ion);GO:0010164(response to cesium ion);GO:0010212(response to ionizing radiation);GO:0010212(response to ionizing radiation)","00100(Steroid biosynthesis);00100(Steroid biosynthesis)","K07419","EC:1.14.14.24","cytochrome P450 family 2 subfamily R member 1 [Source:HGNC Symbol;Acc:HGNC:20580]",{"v":0.586796265500443,"d":"0.59"},{"v":1.08097776860053,"d":"1.08"},{"v":0.542838421422976,"d":"0.54"},{"v":-0.881405258370281,"d":"-0.88"},{"v":0.0904846346542061,"d":"0.09"},{"v":0.623989348123097,"d":"0.62"},"down","no"]
["ENSG00000015153","YAF2","ENST00000534854;ENST00000555248;ENST00000552109;ENST00000548917;ENST00000546782;ENST00000541702;ENST00000550315;ENST00000551528;ENST00000552928;ENST00000551268;ENST00000546726;ENST00000547724;ENST00000327791;ENST00000547254","GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0005515(protein binding);GO:0003713(transcription coactivator activity);GO:0045893(positive regulation of transcription, DNA-templated);GO:0003714(transcription corepressor activity);GO:0045892(negative regulation of transcription, DNA-templated);GO:0045892(negative regulation of transcription, DNA-templated)","NA","NA","NA","YY1 associated factor 2 [Source:HGNC Symbol;Acc:HGNC:17363]",{"v":0.200387433065781,"d":"0.20"},{"v":0.3683984821478,"d":"0.37"},{"v":0.543942070275377,"d":"0.54"},{"v":-0.878475081971733,"d":"-0.88"},{"v":0.0908291189375447,"d":"0.09"},{"v":0.625641971694954,"d":"0.63"},"down","no"]
["MSTRG.12419","ARHGAP26","ENST00000418236;ENST00000378004;ENST00000274498;ENST00000425417;ENST00000461314;ENST00000489924;ENST00000477867;ENST00000443045;ENST00000464838;ENST00000469396;ENST00000475287;ENST00000486650;ENST00000419676;ENST00000424007;ENST00000470032","GO:0005737(cytoplasm);GO:0007165(signal transduction);GO:0043547(positive regulation of GTPase activity);GO:0030036(actin cytoskeleton organization);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0005096(GTPase activator activity);GO:0030054(cell junction);GO:0007399(nervous system development);GO:0051056(regulation of small GTPase mediated signal transduction);GO:0005925(focal adhesion);GO:0005575(cellular_component);GO:0005829(cytosol);GO:0005543(phospholipid binding);GO:0005543(phospholipid binding)","NA","NA","NA","Rho GTPase activating protein 26 [Source:HGNC Symbol;Acc:HGNC:17073]",{"v":13.1396838855923,"d":"13.14"},{"v":5.01712864081816,"d":"5.02"},{"v":2.61896491524873,"d":"2.62"},{"v":1.38899673287075,"d":"1.39"},{"v":0.0908320299903292,"d":"0.09"},{"v":0.625641971694954,"d":"0.63"},"up","no"]
["MSTRG.12125","NSA2","ENST00000610426;ENST00000296802;ENST00000515524;ENST00000514918","GO:0003723(RNA binding);GO:0005634(nucleus);GO:0030529(intracellular ribonucleoprotein complex);GO:0042254(ribosome biogenesis);GO:0005730(nucleolus);GO:0006364(rRNA processing);GO:0030687(preribosome, large subunit precursor);GO:0000470(maturation of LSU-rRNA);GO:0000460(maturation of 5.8S rRNA);GO:0000460(maturation of 5.8S rRNA)","NA","NA","NA","NSA2, ribosome biogenesis homolog [Source:HGNC Symbol;Acc:HGNC:30728]",{"v":8.59001692180572,"d":"8.59"},{"v":15.4844805036276,"d":"15.48"},{"v":0.554750087986052,"d":"0.55"},{"v":-0.850090103646633,"d":"-0.85"},{"v":0.0909674189606389,"d":"0.09"},{"v":0.626018830242817,"d":"0.63"},"down","no"]
["MSTRG.3633","IKBIP","ENST00000299157;ENST00000393042;ENST00000342502","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005515(protein binding);GO:0010165(response to X-ray);GO:0010165(response to X-ray)","NA","NA","NA","IKBKB interacting protein [Source:HGNC Symbol;Acc:HGNC:26430]",{"v":2.35668678501081,"d":"2.36"},{"v":4.27159351717511,"d":"4.27"},{"v":0.551711387222381,"d":"0.55"},{"v":-0.858014337146609,"d":"-0.86"},{"v":0.0910597428952177,"d":"0.09"},{"v":0.626018830242817,"d":"0.63"},"down","no"]
["ENSG00000162910","MRPL55","ENST00000348259;ENST00000336520;ENST00000366735;ENST00000366746;ENST00000495899;ENST00000366733;ENST00000492170;ENST00000366732;ENST00000366738;ENST00000475832;ENST00000366739;ENST00000366741;ENST00000457264;ENST00000489430;ENST00000411464;ENST00000476267;ENST00000295008;ENST00000366742;ENST00000473066;ENST00000483159;ENST00000495434;ENST00000366744;ENST00000366731;ENST00000366740;ENST00000465268;ENST00000497758","GO:0006412(translation);GO:0030529(intracellular ribonucleoprotein complex);GO:0003735(structural constituent of ribosome);GO:0005840(ribosome);GO:0005739(mitochondrion);GO:0005762(mitochondrial large ribosomal subunit);GO:0005743(mitochondrial inner membrane);GO:0070125(mitochondrial translational elongation);GO:0070126(mitochondrial translational termination);GO:0070126(mitochondrial translational termination)","NA","NA","NA","mitochondrial ribosomal protein L55 [Source:HGNC Symbol;Acc:HGNC:16686]",{"v":2.96661125556734,"d":"2.97"},{"v":5.44567584358431,"d":"5.45"},{"v":0.544764569316475,"d":"0.54"},{"v":-0.876295219242268,"d":"-0.88"},{"v":0.0910715500288609,"d":"0.09"},{"v":0.626018830242817,"d":"0.63"},"down","no"]
["MSTRG.6675","C17orf75","ENST00000577809;ENST00000583104;ENST00000580294;ENST00000582073;ENST00000583334;ENST00000225805;ENST00000581747;ENST00000583774;ENST00000580485;ENST00000578215","GO:0003674(molecular_function);GO:0005575(cellular_component);GO:0005575(cellular_component)","NA","NA","NA","chromosome 17 open reading frame 75 [Source:HGNC Symbol;Acc:HGNC:30173]",{"v":0.311576479790941,"d":"0.31"},{"v":0.576826688675958,"d":"0.58"},{"v":0.540156143791007,"d":"0.54"},{"v":-0.888551585184325,"d":"-0.89"},{"v":0.0911230550472465,"d":"0.09"},{"v":0.626018830242817,"d":"0.63"},"down","no"]
["MSTRG.9090","MAP3K2","MSTRG.9090.2;ENST00000409947;ENST00000344908;ENST00000409179","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0000165(MAPK cascade);GO:0016310(phosphorylation);GO:0005515(protein binding);GO:0004709(MAP kinase kinase kinase activity);GO:0000187(activation of MAPK activity);GO:0045893(positive regulation of transcription, DNA-templated);GO:0000186(activation of MAPKK activity);GO:0019901(protein kinase binding);GO:0071260(cellular response to mechanical stimulus);GO:0042981(regulation of apoptotic process);GO:0007346(regulation of mitotic cell cycle);GO:0007257(activation of JUN kinase activity);GO:0005622(intracellular);GO:0005622(intracellular)","04010(MAPK signaling pathway);04540(Gap junction);04912(GnRH signaling pathway);04912(GnRH signaling pathway)","K04420","EC:2.7.11.25","mitogen-activated protein kinase kinase kinase 2 [Source:HGNC Symbol;Acc:HGNC:6854]",{"v":3.76007636545769,"d":"3.76"},{"v":6.77507429222798,"d":"6.78"},{"v":0.554986735683631,"d":"0.55"},{"v":-0.849474803770794,"d":"-0.85"},{"v":0.091200048819039,"d":"0.09"},{"v":0.626018830242817,"d":"0.63"},"down","no"]
["MSTRG.5580","MEFV","ENST00000541159;ENST00000219596;ENST00000542898;ENST00000537682;ENST00000576315;ENST00000536980;ENST00000538326;ENST00000339854;ENST00000539145;ENST00000536379;ENST00000570511;ENST00000572244;ENST00000539154","GO:0050728(negative regulation of inflammatory response);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0005622(intracellular);GO:0003779(actin binding);GO:0005856(cytoskeleton);GO:0042995(cell projection);GO:0005515(protein binding);GO:0005874(microtubule);GO:0031410(cytoplasmic vesicle);GO:0002376(immune system process);GO:0045087(innate immune response);GO:0006954(inflammatory response);GO:0042802(identical protein binding);GO:0005829(cytosol);GO:0005875(microtubule associated complex);GO:0030027(lamellipodium);GO:0010508(positive regulation of autophagy);GO:0005776(autophagosome);GO:0001726(ruffle);GO:2001056(positive regulation of cysteine-type endopeptidase activity);GO:0034341(response to interferon-gamma);GO:0032691(negative regulation of interleukin-1 beta production);GO:0032695(negative regulation of interleukin-12 production);GO:0071641(negative regulation of macrophage inflammatory protein 1 alpha production);GO:1900016(negative regulation of cytokine production involved in inflammatory response);GO:1900226(negative regulation of NLRP3 inflammasome complex assembly);GO:1900226(negative regulation of NLRP3 inflammasome complex assembly)","04621(NOD-like receptor signaling pathway);04621(NOD-like receptor signaling pathway)","K12803","NA","MEFV, pyrin innate immunity regulator [Source:HGNC Symbol;Acc:HGNC:6998]",{"v":17.7718209300685,"d":"17.77"},{"v":6.78610958974891,"d":"6.79"},{"v":2.61885262756655,"d":"2.62"},{"v":1.38893487623641,"d":"1.39"},{"v":0.091210183481516,"d":"0.09"},{"v":0.626018830242817,"d":"0.63"},"up","no"]
["MSTRG.15199","RPS6KA3","MSTRG.15199.2;ENST00000379565;MSTRG.15199.3;ENST00000492128;ENST00000438357","GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0016740(transferase activity);GO:0000287(magnesium ion binding);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0035556(intracellular signal transduction);GO:0005515(protein binding);GO:0007049(cell cycle);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0032496(response to lipopolysaccharide);GO:0043066(negative regulation of apoptotic process);GO:0007165(signal transduction);GO:0007417(central nervous system development);GO:0045597(positive regulation of cell differentiation);GO:0001501(skeletal system development);GO:0030307(positive regulation of cell growth);GO:0043154(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process);GO:0043027(cysteine-type endopeptidase inhibitor activity involved in apoptotic process);GO:0043620(regulation of DNA-templated transcription in response to stress);GO:0002224(toll-like receptor signaling pathway);GO:0006915(apoptotic process);GO:0019901(protein kinase binding);GO:0018105(peptidyl-serine phosphorylation);GO:0043555(regulation of translation in response to stress);GO:0043555(regulation of translation in response to stress)","04010(MAPK signaling pathway);04150(mTOR signaling pathway);04114(Oocyte meiosis);04914(Progesterone-mediated oocyte maturation);04720(Long-term potentiation);04722(Neurotrophin signaling pathway);04931(Insulin resistance);04931(Insulin resistance)","K04373","EC:2.7.11.1","ribosomal protein S6 kinase A3 [Source:HGNC Symbol;Acc:HGNC:10432]",{"v":16.1491650126497,"d":"16.15"},{"v":6.17692110231725,"d":"6.18"},{"v":2.61443601838971,"d":"2.61"},{"v":1.38649976435904,"d":"1.39"},{"v":0.0914083927328719,"d":"0.09"},{"v":0.626928086956987,"d":"0.63"},"up","no"]
["ENSG00000183023","SLC8A1","ENST00000406785;ENST00000403092;ENST00000455476;ENST00000406391;ENST00000405901;ENST00000417271;ENST00000408028;ENST00000402441;ENST00000407929","GO:0010881(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion);GO:0002027(regulation of heart rate);GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0055085(transmembrane transport);GO:0046872(metal ion binding);GO:0005654(nucleoplasm);GO:0005886(plasma membrane);GO:0006811(ion transport);GO:0015297(antiporter activity);GO:0006814(sodium ion transport);GO:0006816(calcium ion transport);GO:0070588(calcium ion transmembrane transport);GO:0007154(cell communication);GO:0005509(calcium ion binding);GO:0005516(calmodulin binding);GO:0060078(regulation of postsynaptic membrane potential);GO:0005515(protein binding);GO:0005432(calcium:sodium antiporter activity);GO:0030501(positive regulation of bone mineralization);GO:0044325(ion channel binding);GO:0006936(muscle contraction);GO:1903779(regulation of cardiac conduction);GO:0042383(sarcolemma);GO:0035725(sodium ion transmembrane transport);GO:0010649(regulation of cell communication by electrical coupling);GO:0060048(cardiac muscle contraction);GO:0071313(cellular response to caffeine);GO:0030018(Z disc);GO:0070509(calcium ion import);GO:0035994(response to muscle stretch);GO:0055074(calcium ion homeostasis);GO:0030506(ankyrin binding);GO:0005887(integral component of plasma membrane);GO:0086012(membrane depolarization during cardiac muscle cell action potential);GO:0030315(T-tubule);GO:0014704(intercalated disc);GO:0008092(cytoskeletal protein binding);GO:0006883(cellular sodium ion homeostasis);GO:0055119(relaxation of cardiac muscle);GO:0086064(cell communication by electrical coupling involved in cardiac conduction);GO:0010882(regulation of cardiac muscle contraction by calcium ion signaling);GO:0002026(regulation of the force of heart contraction);GO:0098735(positive regulation of the force of heart contraction);GO:0014829(vascular smooth muscle contraction);GO:0044557(relaxation of smooth muscle);GO:0051481(negative regulation of cytosolic calcium ion concentration);GO:0055013(cardiac muscle cell development);GO:0060401(cytosolic calcium ion transport);GO:0060402(calcium ion transport into cytosol);GO:0097369(sodium ion import);GO:0099580(ion antiporter activity involved in regulation of postsynaptic membrane potential);GO:0001666(response to hypoxia);GO:0002028(regulation of sodium ion transport);GO:0006874(cellular calcium ion homeostasis);GO:0007204(positive regulation of cytosolic calcium ion concentration);GO:0007584(response to nutrient);GO:0009749(response to glucose);GO:0010763(positive regulation of fibroblast migration);GO:0021537(telencephalon development);GO:0033198(response to ATP);GO:0035902(response to immobilization stress);GO:0042493(response to drug);GO:0042542(response to hydrogen peroxide);GO:0051924(regulation of calcium ion transport);GO:0071320(cellular response to cAMP);GO:0071436(sodium ion export);GO:0071456(cellular response to hypoxia);GO:0005739(mitochondrion);GO:0005874(microtubule);GO:0042995(cell projection);GO:0043197(dendritic spine);GO:0043198(dendritic shaft);GO:0045211(postsynaptic membrane);GO:0045211(postsynaptic membrane)","04371(Apelin signaling pathway);04020(Calcium signaling pathway);04022(cGMP - PKG signaling pathway);04260(Cardiac muscle contraction);04261(Adrenergic signaling in cardiomyocytes);04974(Protein digestion and absorption);04978(Mineral absorption);04961(Endocrine and other factor-regulated calcium reabsorption);04740(Olfactory transduction);05410(Hypertrophic cardiomyopathy (HCM));05412(Arrhythmogenic right ventricular cardiomyopathy (ARVC));05414(Dilated cardiomyopathy (DCM));05414(Dilated cardiomyopathy (DCM))","K05849","NA","solute carrier family 8 member A1 [Source:HGNC Symbol;Acc:HGNC:11068]",{"v":1.89300743321777,"d":"1.89"},{"v":0.722769467521212,"d":"0.72"},{"v":2.61910265760114,"d":"2.62"},{"v":1.3890726082603,"d":"1.39"},{"v":0.0915996216057434,"d":"0.09"},{"v":0.626928086956987,"d":"0.63"},"up","no"]
["ENSG00000178896","EXOSC4","ENST00000316052;ENST00000527954;ENST00000525936","GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0045111(intermediate filament cytoskeleton);GO:0005515(protein binding);GO:0005730(nucleolus);GO:0006364(rRNA processing);GO:0000956(nuclear-transcribed mRNA catabolic process);GO:0005654(nucleoplasm);GO:0043488(regulation of mRNA stability);GO:0090503(RNA phosphodiester bond hydrolysis, exonucleolytic);GO:0030307(positive regulation of cell growth);GO:0043928(exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay);GO:0071044(histone mRNA catabolic process);GO:0017091(AU-rich element binding);GO:0051607(defense response to virus);GO:0035327(transcriptionally active chromatin);GO:0071028(nuclear mRNA surveillance);GO:0000178(exosome (RNase complex));GO:0000460(maturation of 5.8S rRNA);GO:0000175(3'-5'-exoribonuclease activity);GO:0034427(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5');GO:0034475(U4 snRNA 3'-end processing);GO:0000177(cytoplasmic exosome (RNase complex));GO:0071051(polyadenylation-dependent snoRNA 3'-end processing);GO:0000176(nuclear exosome (RNase complex));GO:0016075(rRNA catabolic process);GO:0031125(rRNA 3'-end processing);GO:0045006(DNA deamination);GO:0045006(DNA deamination)","03018(RNA degradation);03018(RNA degradation)","K11600","NA","exosome component 4 [Source:HGNC Symbol;Acc:HGNC:18189]",{"v":1.48740561620469,"d":"1.49"},{"v":2.7270687228145,"d":"2.73"},{"v":0.54542285779641,"d":"0.55"},{"v":-0.874552932334015,"d":"-0.87"},{"v":0.0916041382888493,"d":"0.09"},{"v":0.626928086956987,"d":"0.63"},"down","no"]
["MSTRG.13210","CDK19","ENST00000368911;ENST00000413605;ENST00000463016;ENST00000457688;ENST00000497709","GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0005634(nucleus);GO:0005829(cytosol);GO:0007346(regulation of mitotic cell cycle);GO:0004693(cyclin-dependent protein serine/threonine kinase activity);GO:0019899(enzyme binding);GO:0043065(positive regulation of apoptotic process);GO:0050729(positive regulation of inflammatory response);GO:0071222(cellular response to lipopolysaccharide);GO:0071222(cellular response to lipopolysaccharide)","NA","NA","NA","cyclin dependent kinase 19 [Source:HGNC Symbol;Acc:HGNC:19338]",{"v":7.06056093312867,"d":"7.06"},{"v":2.69572461625734,"d":"2.70"},{"v":2.61916995918201,"d":"2.62"},{"v":1.38910967989214,"d":"1.39"},{"v":0.091609716799111,"d":"0.09"},{"v":0.626928086956987,"d":"0.63"},"up","no"]
["MSTRG.10195","IGLV7-43","ENST00000390298","GO:0016020(membrane);GO:0005886(plasma membrane);GO:0005576(extracellular region);GO:0006508(proteolysis);GO:0006955(immune response);GO:0002376(immune system process);GO:0003823(antigen binding);GO:0002250(adaptive immune response);GO:0004252(serine-type endopeptidase activity);GO:0006898(receptor-mediated endocytosis);GO:0006956(complement activation);GO:0006958(complement activation, classical pathway);GO:0030449(regulation of complement activation);GO:0038095(Fc-epsilon receptor signaling pathway);GO:0038096(Fc-gamma receptor signaling pathway involved in phagocytosis);GO:0050776(regulation of immune response);GO:0050900(leukocyte migration)","NA","NA","NA","immunoglobulin lambda variable 7-43 [Source:HGNC Symbol;Acc:HGNC:5929]",{"v":22.60207,"d":"22.60"},{"v":8.52822,"d":"8.53"},{"v":2.6502681685041,"d":"2.65"},{"v":1.40613834676895,"d":"1.41"},{"v":0.0916125862021878,"d":"0.09"},{"v":0.626928086956987,"d":"0.63"},"up","no"]
["MSTRG.15498","MECP2","ENST00000303391;ENST00000628176;ENST00000460227;ENST00000453960;ENST00000486506;ENST00000626422;ENST00000407218;ENST00000630151;ENST00000637917;ENST00000629277;ENST00000481807;ENST00000627864;ENST00000611468","GO:0005739(mitochondrion);GO:0005634(nucleus);GO:0003723(RNA binding);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0005515(protein binding);GO:0005615(extracellular space);GO:0010385(double-stranded methylated DNA binding);GO:0098794(postsynapse);GO:0005829(cytosol);GO:0008327(methyl-CpG binding);GO:0047485(protein N-terminus binding);GO:0019904(protein domain specific binding);GO:0045892(negative regulation of transcription, DNA-templated);GO:0003714(transcription corepressor activity);GO:0000792(heterochromatin);GO:0009314(response to radiation);GO:0008284(positive regulation of cell proliferation);GO:0010971(positive regulation of G2/M transition of mitotic cell cycle);GO:0000930(gamma-tubulin complex);GO:0005813(centrosome);GO:0007052(mitotic spindle organization);GO:0007626(locomotory behavior);GO:0090063(positive regulation of microtubule nucleation);GO:0001078(transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0003682(chromatin binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0003729(mRNA binding);GO:0008134(transcription factor binding);GO:0035197(siRNA binding);GO:0001662(behavioral fear response);GO:0001666(response to hypoxia);GO:0001964(startle response);GO:0001976(neurological system process involved in regulation of systemic arterial blood pressure);GO:0002087(regulation of respiratory gaseous exchange by neurological system process);GO:0006020(inositol metabolic process);GO:0006122(mitochondrial electron transport, ubiquinol to cytochrome c);GO:0006342(chromatin silencing);GO:0006349(regulation of gene expression by genetic imprinting);GO:0006541(glutamine metabolic process);GO:0006576(cellular biogenic amine metabolic process);GO:0007268(chemical synaptic transmission);GO:0007416(synapse assembly);GO:0007420(brain development);GO:0007585(respiratory gaseous exchange);GO:0007612(learning);GO:0007613(memory);GO:0007616(long-term memory);GO:0008104(protein localization);GO:0008211(glucocorticoid metabolic process);GO:0008344(adult locomotory behavior);GO:0008542(visual learning);GO:0009405(pathogenesis);GO:0009791(post-embryonic development);GO:0010468(regulation of gene expression);GO:0016358(dendrite development);GO:0016571(histone methylation);GO:0016573(histone acetylation);GO:0019230(proprioception);GO:0019233(sensory perception of pain);GO:0021549(cerebellum development);GO:0021591(ventricular system development);GO:0030182(neuron differentiation);GO:0031061(negative regulation of histone methylation);GO:0031175(neuron projection development);GO:0032048(cardiolipin metabolic process);GO:0033555(multicellular organismal response to stress);GO:0035067(negative regulation of histone acetylation);GO:0035176(social behavior);GO:0040029(regulation of gene expression, epigenetic);GO:0042551(neuron maturation);GO:0043524(negative regulation of neuron apoptotic process);GO:0045893(positive regulation of transcription, DNA-templated);GO:0046470(phosphatidylcholine metabolic process);GO:0048167(regulation of synaptic plasticity);GO:0050432(catecholamine secretion);GO:0050884(neuromuscular process controlling posture);GO:0050905(neuromuscular process);GO:0051151(negative regulation of smooth muscle cell differentiation);GO:0051965(positive regulation of synapse assembly);GO:0060079(excitatory postsynaptic potential);GO:0060291(long-term synaptic potentiation);GO:1900114(positive regulation of histone H3-K9 trimethylation);GO:2000820(negative regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation);GO:0005737(cytoplasm);GO:0005737(cytoplasm)","NA","NA","NA","methyl-CpG binding protein 2 [Source:HGNC Symbol;Acc:HGNC:6990]",{"v":4.17003953049113,"d":"4.17"},{"v":1.59309309653708,"d":"1.59"},{"v":2.61757428963541,"d":"2.62"},{"v":1.38823048300811,"d":"1.39"},{"v":0.091765097253419,"d":"0.09"},{"v":0.627601928388666,"d":"0.63"},"up","no"]
["MSTRG.12741","HIST1H2BK","MSTRG.12741.1","NA","NA","NA","NA",null,{"v":29.052301,"d":"29.05"},{"v":52.261795,"d":"52.26"},{"v":0.55589940988441,"d":"0.56"},{"v":-0.847104244294619,"d":"-0.85"},{"v":0.0919108903365475,"d":"0.09"},{"v":0.628024533181481,"d":"0.63"},"down","no"]
["MSTRG.7804","SLC44A2","ENST00000407327;ENST00000588393;ENST00000589561;ENST00000588465;ENST00000586078;ENST00000335757;ENST00000590857;ENST00000591194;ENST00000590475;ENST00000588409;ENST00000592293;ENST00000586549;ENST00000588214","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005765(lysosomal membrane);GO:0004871(signal transducer activity);GO:0007165(signal transduction);GO:0005886(plasma membrane);GO:0070062(extracellular exosome);GO:0055085(transmembrane transport);GO:0043312(neutrophil degranulation);GO:0035579(specific granule membrane);GO:0043123(positive regulation of I-kappaB kinase/NF-kappaB signaling);GO:0006656(phosphatidylcholine biosynthetic process);GO:0015220(choline transmembrane transporter activity);GO:0015871(choline transport);GO:0015871(choline transport)","05231(Choline metabolism in cancer);05231(Choline metabolism in cancer)","K15377","NA","solute carrier family 44 member 2 [Source:HGNC Symbol;Acc:HGNC:17292]",{"v":46.9354614467024,"d":"46.94"},{"v":17.9690040763037,"d":"17.97"},{"v":2.61202352937288,"d":"2.61"},{"v":1.38516789288613,"d":"1.39"},{"v":0.0919350474820045,"d":"0.09"},{"v":0.628024533181481,"d":"0.63"},"up","no"]
["MSTRG.10782","CRTAP","ENST00000320954;ENST00000449224","GO:0005783(endoplasmic reticulum);GO:0005576(extracellular region);GO:0005578(proteinaceous extracellular matrix);GO:0005615(extracellular space);GO:0050821(protein stabilization);GO:0018400(peptidyl-proline hydroxylation to 3-hydroxy-L-proline);GO:0005788(endoplasmic reticulum lumen);GO:0032403(protein complex binding);GO:0061077(chaperone-mediated protein folding);GO:0007283(spermatogenesis);GO:1901874(negative regulation of post-translational protein modification);GO:0032991(macromolecular complex);GO:0032991(macromolecular complex)","NA","NA","NA","cartilage associated protein [Source:HGNC Symbol;Acc:HGNC:2379]",{"v":12.6469146407767,"d":"12.65"},{"v":4.84222718446602,"d":"4.84"},{"v":2.61179704276336,"d":"2.61"},{"v":1.38504279245281,"d":"1.39"},{"v":0.0921282807914935,"d":"0.09"},{"v":0.628613294050651,"d":"0.63"},"up","no"]
["ENSG00000198879","SFMBT2","ENST00000397167;ENST00000379711;ENST00000379713","GO:0005634(nucleus);GO:0016607(nuclear speck);GO:0043231(intracellular membrane-bounded organelle);GO:0006355(regulation of transcription, DNA-templated);GO:0016235(aggresome);GO:0005515(protein binding);GO:0010629(negative regulation of gene expression);GO:0042393(histone binding);GO:0042393(histone binding)","NA","NA","NA","Scm-like with four mbt domains 2 [Source:HGNC Symbol;Acc:HGNC:20256]",{"v":2.37130807193811,"d":"2.37"},{"v":0.906624931578419,"d":"0.91"},{"v":2.61553371117834,"d":"2.62"},{"v":1.38710536479182,"d":"1.39"},{"v":0.0921294950894866,"d":"0.09"},{"v":0.628613294050651,"d":"0.63"},"up","no"]
["MSTRG.8733","WDPCP","ENST00000409835;ENST00000409562;ENST00000398544;ENST00000417238;ENST00000487280;ENST00000484073;ENST00000409354;ENST00000409120;ENST00000462652;ENST00000272321","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005886(plasma membrane);GO:0005856(cytoskeleton);GO:0042995(cell projection);GO:0060271(cilium assembly);GO:0005929(cilium);GO:0030030(cell projection organization);GO:0005938(cell cortex);GO:0005930(axoneme);GO:0016324(apical plasma membrane);GO:0032880(regulation of protein localization);GO:0001822(kidney development);GO:0002093(auditory receptor cell morphogenesis);GO:0007224(smoothened signaling pathway);GO:0007399(nervous system development);GO:0010762(regulation of fibroblast migration);GO:0016476(regulation of embryonic cell shape);GO:0032185(septin cytoskeleton organization);GO:0042733(embryonic digit morphogenesis);GO:0043010(camera-type eye development);GO:0044782(cilium organization);GO:0045184(establishment of protein localization);GO:0048568(embryonic organ development);GO:0051893(regulation of focal adhesion assembly);GO:0055123(digestive system development);GO:0060021(palate development);GO:0060541(respiratory system development);GO:0072358(cardiovascular system development);GO:0090521(glomerular visceral epithelial cell migration);GO:1900027(regulation of ruffle assembly);GO:2000114(regulation of establishment of cell polarity);GO:0097541(axonemal basal plate);GO:0097541(axonemal basal plate)","NA","NA","NA","WD repeat containing planar cell polarity effector [Source:HGNC Symbol;Acc:HGNC:28027]",{"v":0.165801313434103,"d":"0.17"},{"v":0.305752752292799,"d":"0.31"},{"v":0.542272513299655,"d":"0.54"},{"v":-0.882910049983761,"d":"-0.88"},{"v":0.0924720907211239,"d":"0.09"},{"v":0.629950252462512,"d":"0.63"},"down","no"]
["MSTRG.11113","NAA50","ENST00000240922;ENST00000493900;ENST00000481432;ENST00000493454;ENST00000497255;ENST00000497525;ENST00000467022;ENST00000630058","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016740(transferase activity);GO:0016746(transferase activity, transferring acyl groups);GO:0005515(protein binding);GO:0008080(N-acetyltransferase activity);GO:0070062(extracellular exosome);GO:0010485(H4 histone acetyltransferase activity);GO:0004596(peptide alpha-N-acetyltransferase activity);GO:0031415(NatA complex);GO:0052858(peptidyl-lysine acetyltransferase activity);GO:0006474(N-terminal protein amino acid acetylation);GO:0043967(histone H4 acetylation);GO:0071962(mitotic sister chromatid cohesion, centromeric);GO:0071962(mitotic sister chromatid cohesion, centromeric)","NA","NA","NA","N(alpha)-acetyltransferase 50, NatE catalytic subunit [Source:HGNC Symbol;Acc:HGNC:29533]",{"v":10.283669466128,"d":"10.28"},{"v":3.93913526211933,"d":"3.94"},{"v":2.61064136716016,"d":"2.61"},{"v":1.38440428325157,"d":"1.38"},{"v":0.0925245212359649,"d":"0.09"},{"v":0.629950252462512,"d":"0.63"},"up","no"]
["MSTRG.6088","PDPR","ENST00000288050;ENST00000567896;ENST00000565186;ENST00000561920;MSTRG.6088.7","GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0016311(dephosphorylation);GO:0005739(mitochondrion);GO:0005759(mitochondrial matrix);GO:0010510(regulation of acetyl-CoA biosynthetic process from pyruvate);GO:0004741([pyruvate dehydrogenase (lipoamide)] phosphatase activity);GO:0004741([pyruvate dehydrogenase (lipoamide)] phosphatase activity)","NA","NA","NA","pyruvate dehydrogenase phosphatase regulatory subunit [Source:HGNC Symbol;Acc:HGNC:30264]",{"v":3.07643341338469,"d":"3.08"},{"v":1.17607820365912,"d":"1.18"},{"v":2.61584085464131,"d":"2.62"},{"v":1.38727477126264,"d":"1.39"},{"v":0.0925306364236923,"d":"0.09"},{"v":0.629950252462512,"d":"0.63"},"up","no"]
["MSTRG.12277","HINT1","ENST00000304043;ENST00000504202;ENST00000511475;ENST00000506908;ENST00000508495;ENST00000513345;ENST00000506207;ENST00000513012;ENST00000508488","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0000166(nucleotide binding);GO:0005829(cytosol);GO:0016787(hydrolase activity);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003824(catalytic activity);GO:0005886(plasma membrane);GO:0006915(apoptotic process);GO:0070062(extracellular exosome);GO:0000118(histone deacetylase complex);GO:0007165(signal transduction);GO:0005856(cytoskeleton);GO:0072332(intrinsic apoptotic signaling pathway by p53 class mediator);GO:0005080(protein kinase C binding);GO:0009154(purine ribonucleotide catabolic process);GO:0050850(positive regulation of calcium-mediated signaling);GO:0050850(positive regulation of calcium-mediated signaling)","NA","NA","NA","histidine triad nucleotide binding protein 1 [Source:HGNC Symbol;Acc:HGNC:4912]",{"v":12.5891153228306,"d":"12.59"},{"v":22.6522748910124,"d":"22.65"},{"v":0.555755012836503,"d":"0.56"},{"v":-0.847479038658492,"d":"-0.85"},{"v":0.0925955934849364,"d":"0.09"},{"v":0.629950252462512,"d":"0.63"},"down","no"]
["MSTRG.6312","ATP2A3","ENST00000397041;ENST00000352011;ENST00000397043;ENST00000576957;ENST00000309890;ENST00000397035;ENST00000570773;ENST00000574202;ENST00000571245;ENST00000572116;ENST00000359983;ENST00000572694;ENST00000572176;ENST00000574999;ENST00000570845","GO:0006810(transport);GO:0005634(nucleus);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0016787(hydrolase activity);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0006811(ion transport);GO:0005388(calcium-transporting ATPase activity);GO:0006816(calcium ion transport);GO:0070588(calcium ion transmembrane transport);GO:0099132(ATP hydrolysis coupled cation transmembrane transport);GO:0033017(sarcoplasmic reticulum membrane);GO:0034220(ion transmembrane transport);GO:0016529(sarcoplasmic reticulum);GO:0031965(nuclear membrane);GO:1903779(regulation of cardiac conduction);GO:0031095(platelet dense tubular network membrane);GO:0031095(platelet dense tubular network membrane)","04020(Calcium signaling pathway);04022(cGMP - PKG signaling pathway);04972(Pancreatic secretion);05010(Alzheimer's disease);05010(Alzheimer's disease)","K05853","EC:3.6.3.8","ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 3 [Source:HGNC Symbol;Acc:HGNC:813]",{"v":35.7045839930364,"d":"35.70"},{"v":13.6927879547367,"d":"13.69"},{"v":2.60754669619237,"d":"2.61"},{"v":1.38269308889535,"d":"1.38"},{"v":0.0925966658876697,"d":"0.09"},{"v":0.629950252462512,"d":"0.63"},"up","no"]
["ENSG00000171202","TMEM126A","ENST00000304511;ENST00000528105;ENST00000525353;ENST00000531366;ENST00000528531;ENST00000532180","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005743(mitochondrial inner membrane);GO:0005739(mitochondrion);GO:0003674(molecular_function);GO:0021554(optic nerve development);GO:0021554(optic nerve development)","NA","NA","NA","transmembrane protein 126A [Source:HGNC Symbol;Acc:HGNC:25382]",{"v":2.48530815139032,"d":"2.49"},{"v":4.56720896292482,"d":"4.57"},{"v":0.54416344239234,"d":"0.54"},{"v":-0.877888057173086,"d":"-0.88"},{"v":0.0926825214085645,"d":"0.09"},{"v":0.630165176298395,"d":"0.63"},"down","no"]
["MSTRG.6956","SCRN2","ENST00000407215;ENST00000290216;ENST00000584123;ENST00000581645;ENST00000581546;ENST00000580428;ENST00000582656;ENST00000584567;ENST00000578840;ENST00000583090;ENST00000582459;ENST00000579856","GO:0005515(protein binding);GO:0006508(proteolysis);GO:0016805(dipeptidase activity);GO:0003674(molecular_function);GO:0008150(biological_process);GO:0070062(extracellular exosome);GO:0006887(exocytosis);GO:0006887(exocytosis)","NA","NA","NA","secernin 2 [Source:HGNC Symbol;Acc:HGNC:30381]",{"v":1.5904247906671,"d":"1.59"},{"v":2.90959296943805,"d":"2.91"},{"v":0.546614185342313,"d":"0.55"},{"v":-0.871405194745494,"d":"-0.87"},{"v":0.0927804179124512,"d":"0.09"},{"v":0.630461669524457,"d":"0.63"},"down","no"]
["MSTRG.3921","RPL21","ENST00000319826;ENST00000326092;ENST00000483765;ENST00000493317;ENST00000311549;ENST00000466550;ENST00000272274;ENST00000461690;ENST00000473558;ENST00000485756","GO:0003723(RNA binding);GO:0016020(membrane);GO:0006412(translation);GO:0030529(intracellular ribonucleoprotein complex);GO:0005622(intracellular);GO:0003735(structural constituent of ribosome);GO:0005840(ribosome);GO:0005829(cytosol);GO:0005515(protein binding);GO:0006413(translational initiation);GO:0006364(rRNA processing);GO:0000184(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay);GO:0019083(viral transcription);GO:0006614(SRP-dependent cotranslational protein targeting to membrane);GO:0022625(cytosolic large ribosomal subunit);GO:0022625(cytosolic large ribosomal subunit)","03010(Ribosome);03010(Ribosome)","K02889","NA","ribosomal protein L21 [Source:HGNC Symbol;Acc:HGNC:10313]",{"v":128.164717893731,"d":"128.16"},{"v":229.730366592708,"d":"229.73"},{"v":0.557891931287238,"d":"0.56"},{"v":-0.841942408846537,"d":"-0.84"},{"v":0.0928985009731293,"d":"0.09"},{"v":0.630531223605278,"d":"0.63"},"down","no"]
["MSTRG.10605","SBF1","ENST00000348911;ENST00000380817;ENST00000470434;ENST00000477234;ENST00000476293;ENST00000399627;ENST00000418590;ENST00000473724","GO:0005634(nucleus);GO:0016021(integral component of membrane);GO:0043547(positive regulation of GTPase activity);GO:0019208(phosphatase regulator activity);GO:0007283(spermatogenesis);GO:0043087(regulation of GTPase activity);GO:0005085(guanyl-nucleotide exchange factor activity);GO:0005789(endoplasmic reticulum membrane);GO:0005829(cytosol);GO:0017112(Rab guanyl-nucleotide exchange factor activity);GO:0061024(membrane organization);GO:0006661(phosphatidylinositol biosynthetic process);GO:0006470(protein dephosphorylation);GO:0008138(protein tyrosine/serine/threonine phosphatase activity);GO:0008138(protein tyrosine/serine/threonine phosphatase activity)","NA","NA","NA","SET binding factor 1 [Source:HGNC Symbol;Acc:HGNC:10542]",{"v":11.801205652791,"d":"11.80"},{"v":4.52675646361614,"d":"4.53"},{"v":2.60698929744583,"d":"2.61"},{"v":1.38238466014485,"d":"1.38"},{"v":0.0928992442597632,"d":"0.09"},{"v":0.630531223605278,"d":"0.63"},"up","no"]
["ENSG00000142207","URB1","ENST00000382751;ENST00000480196","GO:0003723(RNA binding);GO:0005634(nucleus);GO:0001650(fibrillar center);GO:0005730(nucleolus);GO:0008150(biological_process);GO:0008150(biological_process)","NA","NA","NA","URB1 ribosome biogenesis 1 homolog (S. cerevisiae) [Source:HGNC Symbol;Acc:HGNC:17344]",{"v":1.49769199476485,"d":"1.50"},{"v":0.571632076782131,"d":"0.57"},{"v":2.62002790885311,"d":"2.62"},{"v":1.38958217960606,"d":"1.39"},{"v":0.0930689517436349,"d":"0.09"},{"v":0.631314098480626,"d":"0.63"},"up","no"]
["ENSG00000165813","CCDC186","ENST00000369287;ENST00000369286;ENST00000497592;ENST00000490661;ENST00000369285","NA","NA","NA","NA","coiled-coil domain containing 186 [Source:HGNC Symbol;Acc:HGNC:24349]",{"v":5.3577632335669,"d":"5.36"},{"v":2.05197832743855,"d":"2.05"},{"v":2.61102330464421,"d":"2.61"},{"v":1.38461533445833,"d":"1.38"},{"v":0.0931602120536564,"d":"0.09"},{"v":0.631564239684245,"d":"0.63"},"up","no"]
["ENSG00000158481","CD1C","ENST00000368170;ENST00000443761","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005886(plasma membrane);GO:0002376(immune system process);GO:0005764(lysosome);GO:0002250(adaptive immune response);GO:0050776(regulation of immune response);GO:0008289(lipid binding);GO:0005768(endosome);GO:0010008(endosome membrane);GO:0005887(integral component of plasma membrane);GO:0030881(beta-2-microglobulin binding);GO:0048007(antigen processing and presentation, exogenous lipid antigen via MHC class Ib);GO:0002286(T cell activation involved in immune response);GO:0030884(exogenous lipid antigen binding);GO:0030883(endogenous lipid antigen binding);GO:0051861(glycolipid binding);GO:0071723(lipopeptide binding);GO:0071723(lipopeptide binding)","04530(Tight junction);04640(Hematopoietic cell lineage);04640(Hematopoietic cell lineage)","K06448","NA","CD1c molecule [Source:HGNC Symbol;Acc:HGNC:1636]",{"v":4.58780157839721,"d":"4.59"},{"v":8.26359173867596,"d":"8.26"},{"v":0.555182507011448,"d":"0.56"},{"v":-0.848965983465103,"d":"-0.85"},{"v":0.0935701264086956,"d":"0.09"},{"v":0.633477789411516,"d":"0.63"},"down","no"]
["ENSG00000144152","FBLN7","ENST00000472377;ENST00000331203;ENST00000272559","GO:0005509(calcium ion binding);GO:0007155(cell adhesion);GO:0005576(extracellular region);GO:0005578(proteinaceous extracellular matrix);GO:0005925(focal adhesion);GO:0008201(heparin binding);GO:0070062(extracellular exosome);GO:0070062(extracellular exosome)","NA","NA","NA","fibulin 7 [Source:HGNC Symbol;Acc:HGNC:26740]",{"v":0.146724509881423,"d":"0.15"},{"v":0.27618877652782,"d":"0.28"},{"v":0.53124718435705,"d":"0.53"},{"v":-0.912544805102385,"d":"-0.91"},{"v":0.0935979388673678,"d":"0.09"},{"v":0.633477789411516,"d":"0.63"},"down","no"]
["MSTRG.8396","MYADM","ENST00000391768;ENST00000391770;ENST00000448420;ENST00000391771;ENST00000336967;ENST00000414489;ENST00000421337;ENST00000391769","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005886(plasma membrane);GO:0045121(membrane raft);GO:0003674(molecular_function);GO:0070062(extracellular exosome);GO:0030335(positive regulation of cell migration);GO:0001726(ruffle);GO:0010629(negative regulation of gene expression);GO:0001933(negative regulation of protein phosphorylation);GO:0061028(establishment of endothelial barrier);GO:0030864(cortical actin cytoskeleton);GO:0005911(cell-cell junction);GO:0031579(membrane raft organization);GO:0030837(negative regulation of actin filament polymerization);GO:1900026(positive regulation of substrate adhesion-dependent cell spreading);GO:0072661(protein targeting to plasma membrane);GO:0034115(negative regulation of heterotypic cell-cell adhesion);GO:0090038(negative regulation of protein kinase C signaling);GO:0090038(negative regulation of protein kinase C signaling)","NA","NA","NA","myeloid associated differentiation marker [Source:HGNC Symbol;Acc:HGNC:7544]",{"v":52.7689020688435,"d":"52.77"},{"v":20.2858984546939,"d":"20.29"},{"v":2.60126028860375,"d":"2.60"},{"v":1.37921076617426,"d":"1.38"},{"v":0.0936061212976975,"d":"0.09"},{"v":0.633477789411516,"d":"0.63"},"up","no"]
["ENSG00000112237","CCNC","ENST00000520429;ENST00000482541;ENST00000520371;ENST00000369220;ENST00000523639;ENST00000627680;ENST00000519617;ENST00000484049;ENST00000523541;ENST00000326298;ENST00000521017;ENST00000523985;ENST00000523310;ENST00000523961;ENST00000518714","GO:0005634(nucleus);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0016592(mediator complex);GO:0006468(protein phosphorylation);GO:0005515(protein binding);GO:0045859(regulation of protein kinase activity);GO:0005654(nucleoplasm);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0016538(cyclin-dependent protein serine/threonine kinase regulator activity);GO:0004674(protein serine/threonine kinase activity);GO:0006367(transcription initiation from RNA polymerase II promoter);GO:0045737(positive regulation of cyclin-dependent protein serine/threonine kinase activity);GO:1901409(positive regulation of phosphorylation of RNA polymerase II C-terminal domain);GO:0000307(cyclin-dependent protein kinase holoenzyme complex);GO:0000307(cyclin-dependent protein kinase holoenzyme complex)","NA","NA","NA","cyclin C [Source:HGNC Symbol;Acc:HGNC:1581]",{"v":1.56036118508239,"d":"1.56"},{"v":2.81324438889853,"d":"2.81"},{"v":0.554648288374733,"d":"0.55"},{"v":-0.850354870204719,"d":"-0.85"},{"v":0.0936754238339564,"d":"0.09"},{"v":0.633577575412776,"d":"0.63"},"down","no"]
["MSTRG.11523","KIAA0232","ENST00000425103;ENST00000307659","GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0005524(ATP binding)","NA","NA","NA","KIAA0232 [Source:HGNC Symbol;Acc:HGNC:28992]",{"v":10.1765766425462,"d":"10.18"},{"v":3.91278670855395,"d":"3.91"},{"v":2.60085136261035,"d":"2.60"},{"v":1.37898395231729,"d":"1.38"},{"v":0.0938258110233733,"d":"0.09"},{"v":0.633794000692655,"d":"0.63"},"up","no"]
["MSTRG.964","S100A12","ENST00000368737","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0046872(metal ion binding);GO:0005509(calcium ion binding);GO:0005829(cytosol);GO:0008270(zinc ion binding);GO:0005886(plasma membrane);GO:0005856(cytoskeleton);GO:0005576(extracellular region);GO:0002376(immune system process);GO:0045087(innate immune response);GO:0006954(inflammatory response);GO:0042742(defense response to bacterium);GO:0006805(xenobiotic metabolic process);GO:0005515(protein binding);GO:0030593(neutrophil chemotaxis);GO:0061844(antimicrobial humoral immune response mediated by antimicrobial peptide);GO:0043312(neutrophil degranulation);GO:0043123(positive regulation of I-kappaB kinase/NF-kappaB signaling);GO:0050663(cytokine secretion);GO:0051092(positive regulation of NF-kappaB transcription factor activity);GO:0034774(secretory granule lumen);GO:0005507(copper ion binding);GO:0050729(positive regulation of inflammatory response);GO:0031640(killing of cells of other organism);GO:0043406(positive regulation of MAP kinase activity);GO:0002548(monocyte chemotaxis);GO:0050832(defense response to fungus);GO:0050786(RAGE receptor binding);GO:0045576(mast cell activation)","NA","NA","NA","S100 calcium binding protein A12 [Source:HGNC Symbol;Acc:HGNC:10489]",{"v":43.554352,"d":"43.55"},{"v":78.034088,"d":"78.03"},{"v":0.558145204439373,"d":"0.56"},{"v":-0.84128759922569,"d":"-0.84"},{"v":0.0939027758817629,"d":"0.09"},{"v":0.633794000692655,"d":"0.63"},"down","no"]
["MSTRG.5133","RPS3AP6","ENST00000484430","NA","NA","NA","NA","ribosomal protein S3A pseudogene 6 [Source:HGNC Symbol;Acc:HGNC:18630]",{"v":68.955605,"d":"68.96"},{"v":123.367271,"d":"123.37"},{"v":0.558945694762106,"d":"0.56"},{"v":-0.839219972289719,"d":"-0.84"},{"v":0.0939084813091203,"d":"0.09"},{"v":0.633794000692655,"d":"0.63"},"down","no"]
["MSTRG.9352","CFLAR;AC007283.1","ENST00000309955;ENST00000341222;ENST00000443227;ENST00000342795;ENST00000395148;ENST00000457277;ENST00000423241;ENST00000439154;ENST00000433445;ENST00000461422;ENST00000461820;ENST00000341582;ENST00000490965;ENST00000425030;ENST00000462763;ENST00000470178;ENST00000440180;ENST00000479953;ENST00000434645;ENST00000474842;ENST00000417748;ENST00000441224;ENST00000460961;ENST00000340870;ENST00000494258;ENST00000470664","GO:0005737(cytoplasm);GO:0042981(regulation of apoptotic process);GO:0043085(positive regulation of catalytic activity);GO:0005515(protein binding);GO:0008234(cysteine-type peptidase activity);GO:0006508(proteolysis);GO:0006915(apoptotic process);GO:0004197(cysteine-type endopeptidase activity);GO:0002020(protease binding);GO:0005123(death receptor binding);GO:0032403(protein complex binding);GO:0001666(response to hypoxia);GO:0010667(negative regulation of cardiac muscle cell apoptotic process);GO:0010976(positive regulation of neuron projection development);GO:0032869(cellular response to insulin stimulus);GO:0033574(response to testosterone);GO:0043066(negative regulation of apoptotic process);GO:0070374(positive regulation of ERK1 and ERK2 cascade);GO:0071364(cellular response to epidermal growth factor stimulus);GO:0071392(cellular response to estradiol stimulus);GO:0071456(cellular response to hypoxia);GO:0071549(cellular response to dexamethasone stimulus);GO:0071732(cellular response to nitric oxide);GO:0072126(positive regulation of glomerular mesangial cell proliferation);GO:1903055(positive regulation of extracellular matrix organization);GO:1903427(negative regulation of reactive oxygen species biosynthetic process);GO:1903845(negative regulation of cellular response to transforming growth factor beta stimulus);GO:1903944(negative regulation of hepatocyte apoptotic process);GO:1904036(negative regulation of epithelial cell apoptotic process);GO:2000347(positive regulation of hepatocyte proliferation);GO:0031264(death-inducing signaling complex);GO:0031265(CD95 death-inducing signaling complex);GO:0045121(membrane raft);GO:0005829(cytosol);GO:0016032(viral process);GO:0043123(positive regulation of I-kappaB kinase/NF-kappaB signaling);GO:1902041(regulation of extrinsic apoptotic signaling pathway via death domain receptors);GO:1902042(negative regulation of extrinsic apoptotic signaling pathway via death domain receptors);GO:0051092(positive regulation of NF-kappaB transcription factor activity);GO:0008047(enzyme activator activity);GO:0097200(cysteine-type endopeptidase activity involved in execution phase of apoptosis);GO:0007519(skeletal muscle tissue development);GO:0014732(skeletal muscle atrophy);GO:0014842(regulation of skeletal muscle satellite cell proliferation);GO:0014866(skeletal myofibril assembly);GO:0043403(skeletal muscle tissue regeneration);GO:0060544(regulation of necroptotic process);GO:0097194(execution phase of apoptosis);GO:1901740(negative regulation of myoblast fusion);GO:2001237(negative regulation of extrinsic apoptotic signaling pathway);GO:0097342(ripoptosome);GO:0097342(ripoptosome)","04064(NF-kappa B signaling pathway);04668(TNF signaling pathway);04140(Autophagy - animal);04210(Apoptosis);04217(Necroptosis);05142(Chagas disease (American trypanosomiasis));05142(Chagas disease (American trypanosomiasis))","K04724","NA","CASP8 and FADD like apoptosis regulator [Source:HGNC Symbol;Acc:HGNC:1876]",{"v":12.8958029126015,"d":"12.90"},{"v":4.96058504119135,"d":"4.96"},{"v":2.59965363067426,"d":"2.60"},{"v":1.37831941610118,"d":"1.38"},{"v":0.0939257276493636,"d":"0.09"},{"v":0.633794000692655,"d":"0.63"},"up","no"]
["MSTRG.1255","FAM129A","ENST00000367511;ENST00000461167;ENST00000487074;ENST00000496299;ENST00000417056","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0001933(negative regulation of protein phosphorylation);GO:0001934(positive regulation of protein phosphorylation);GO:0034976(response to endoplasmic reticulum stress);GO:0045727(positive regulation of translation);GO:0003674(molecular_function);GO:0070062(extracellular exosome);GO:0006417(regulation of translation);GO:0006417(regulation of translation)","NA","NA","NA","family with sequence similarity 129 member A [Source:HGNC Symbol;Acc:HGNC:16784]",{"v":82.8912097804587,"d":"82.89"},{"v":31.9274716877688,"d":"31.93"},{"v":2.59623469691193,"d":"2.60"},{"v":1.37642080736098,"d":"1.38"},{"v":0.0940446275933777,"d":"0.09"},{"v":0.633798597884571,"d":"0.63"},"up","no"]
["MSTRG.4093","ABHD13","ENST00000375898","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016787(hydrolase activity)","NA","NA","NA","abhydrolase domain containing 13 [Source:HGNC Symbol;Acc:HGNC:20293]",{"v":2.921649,"d":"2.92"},{"v":5.239558,"d":"5.24"},{"v":0.557613638402323,"d":"0.56"},{"v":-0.842662247069169,"d":"-0.84"},{"v":0.0940552207795432,"d":"0.09"},{"v":0.633798597884571,"d":"0.63"},"down","no"]
["MSTRG.5627","UBN1","ENST00000262376;ENST00000396658;ENST00000590769;ENST00000586716;ENST00000586152;ENST00000587027;ENST00000592120;ENST00000585857","GO:0005634(nucleus);GO:0006325(chromatin organization);GO:0005654(nucleoplasm);GO:0016569(covalent chromatin modification);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0016604(nuclear body);GO:0030054(cell junction);GO:0005923(bicellular tight junction);GO:0016032(viral process);GO:0010923(negative regulation of phosphatase activity);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0016605(PML body);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0006336(DNA replication-independent nucleosome assembly);GO:0006336(DNA replication-independent nucleosome assembly)","NA","NA","NA","ubinuclein 1 [Source:HGNC Symbol;Acc:HGNC:12506]",{"v":17.1505676450708,"d":"17.15"},{"v":6.60145847549994,"d":"6.60"},{"v":2.59799674704035,"d":"2.60"},{"v":1.37739962438407,"d":"1.38"},{"v":0.0941276938936121,"d":"0.09"},{"v":0.633798597884571,"d":"0.63"},"up","no"]
["MSTRG.9511","COPS9","ENST00000607357;ENST00000491765;ENST00000403160;ENST00000489698;ENST00000307266","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0000790(nuclear chromatin);GO:0005654(nucleoplasm);GO:0005515(protein binding);GO:0008180(COP9 signalosome);GO:0008284(positive regulation of cell proliferation);GO:0034644(cellular response to UV);GO:0034644(cellular response to UV)","NA","NA","NA","COP9 signalosome subunit 9 [Source:HGNC Symbol;Acc:HGNC:21314]",{"v":1.97519906326631,"d":"1.98"},{"v":3.5617574139284,"d":"3.56"},{"v":0.554557437163523,"d":"0.55"},{"v":-0.850591202544422,"d":"-0.85"},{"v":0.0941447155214746,"d":"0.09"},{"v":0.633798597884571,"d":"0.63"},"down","no"]
["MSTRG.8252","PRKD2","ENST00000433867;ENST00000600194;ENST00000291281;ENST00000593363;ENST00000597088;ENST00000597390;ENST00000602155;ENST00000597641;ENST00000597589;ENST00000595132;ENST00000599019;ENST00000599464;ENST00000595515;ENST00000601806;ENST00000593492","GO:0045766(positive regulation of angiogenesis);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0005737(cytoplasm);GO:0005634(nucleus);GO:0061154(endothelial tube morphogenesis);GO:0043536(positive regulation of blood vessel endothelial cell migration);GO:0016020(membrane);GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0035556(intracellular signal transduction);GO:0007155(cell adhesion);GO:0005794(Golgi apparatus);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0004697(protein kinase C activity);GO:0002376(immune system process);GO:0002250(adaptive immune response);GO:0050862(positive regulation of T cell receptor signaling pathway);GO:0033138(positive regulation of peptidyl-serine phosphorylation);GO:0001938(positive regulation of endothelial cell proliferation);GO:0051092(positive regulation of NF-kappaB transcription factor activity);GO:0070374(positive regulation of ERK1 and ERK2 cascade);GO:0045785(positive regulation of cell adhesion);GO:0001525(angiogenesis);GO:0051091(positive regulation of sequence-specific DNA binding transcription factor activity);GO:0030148(sphingolipid biosynthetic process);GO:0010595(positive regulation of endothelial cell migration);GO:0018107(peptidyl-threonine phosphorylation);GO:0035924(cellular response to vascular endothelial growth factor stimulus);GO:0048010(vascular endothelial growth factor receptor signaling pathway);GO:1902533(positive regulation of intracellular signal transduction);GO:0018105(peptidyl-serine phosphorylation);GO:0032743(positive regulation of interleukin-2 production);GO:0008219(cell death);GO:2000573(positive regulation of DNA biosynthetic process);GO:0032757(positive regulation of interleukin-8 production);GO:0046777(protein autophosphorylation);GO:0038033(positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway);GO:2001028(positive regulation of endothelial cell chemotaxis);GO:0005080(protein kinase C binding);GO:0030949(positive regulation of vascular endothelial growth factor receptor signaling pathway);GO:0032793(positive regulation of CREB transcription factor activity);GO:1901727(positive regulation of histone deacetylase activity);GO:0050852(T cell receptor signaling pathway);GO:0089700(protein kinase D signaling);GO:0045743(positive regulation of fibroblast growth factor receptor signaling pathway);GO:0005622(intracellular);GO:0005622(intracellular)","04015(Rap1 signaling pathway);04925(Aldosterone synthesis and secretion);04925(Aldosterone synthesis and secretion)","K06070","EC:2.7.11.13","protein kinase D2 [Source:HGNC Symbol;Acc:HGNC:17293]",{"v":14.1525475095483,"d":"14.15"},{"v":5.44045696107235,"d":"5.44"},{"v":2.60135271923165,"d":"2.60"},{"v":1.37926202857194,"d":"1.38"},{"v":0.0942760730072641,"d":"0.09"},{"v":0.634315200366952,"d":"0.63"},"up","no"]
["MSTRG.9765","TOMM34","ENST00000372813","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0005739(mitochondrion);GO:0005515(protein binding);GO:0005741(mitochondrial outer membrane);GO:0016021(integral component of membrane);GO:0006626(protein targeting to mitochondrion);GO:0031072(heat shock protein binding)","NA","NA","NA","translocase of outer mitochondrial membrane 34 [Source:HGNC Symbol;Acc:HGNC:15746]",{"v":2.464691,"d":"2.46"},{"v":4.444833,"d":"4.44"},{"v":0.554506997225768,"d":"0.55"},{"v":-0.850722429271843,"d":"-0.85"},{"v":0.0943323146569683,"d":"0.09"},{"v":0.634326097343007,"d":"0.63"},"down","no"]
["ENSG00000140543","DET1","ENST00000557842;ENST00000564406;ENST00000606927;ENST00000268148;ENST00000444300","GO:0005634(nucleus);GO:0016567(protein ubiquitination);GO:0005515(protein binding);GO:0031625(ubiquitin protein ligase binding);GO:0032403(protein complex binding);GO:0006461(protein complex assembly);GO:0032436(positive regulation of proteasomal ubiquitin-dependent protein catabolic process);GO:0031464(Cul4A-RING E3 ubiquitin ligase complex);GO:1990756(protein binding, bridging involved in substrate recognition for ubiquitination);GO:1990756(protein binding, bridging involved in substrate recognition for ubiquitination)","04120(Ubiquitin mediated proteolysis);04120(Ubiquitin mediated proteolysis)","K10571","NA","de-etiolated homolog 1 (Arabidopsis) [Source:HGNC Symbol;Acc:HGNC:25477]",{"v":0.586131503575077,"d":"0.59"},{"v":0.22126102933022,"d":"0.22"},{"v":2.64904988171373,"d":"2.65"},{"v":1.40547500996781,"d":"1.41"},{"v":0.0944330959254589,"d":"0.09"},{"v":0.63463630959627,"d":"0.63"},"up","no"]
["ENSG00000080573","COL5A3","ENST00000264828","GO:0005576(extracellular region);GO:0005581(collagen trimer);GO:0005578(proteinaceous extracellular matrix);GO:0005201(extracellular matrix structural constituent);GO:0070062(extracellular exosome);GO:0030574(collagen catabolic process);GO:0005788(endoplasmic reticulum lumen);GO:0030198(extracellular matrix organization);GO:0030199(collagen fibril organization);GO:0005518(collagen binding);GO:0043588(skin development);GO:0005588(collagen type V trimer);GO:0008201(heparin binding);GO:0043394(proteoglycan binding);GO:0007160(cell-matrix adhesion);GO:0031012(extracellular matrix)","04974(Protein digestion and absorption)","K19721","NA","collagen type V alpha 3 chain [Source:HGNC Symbol;Acc:HGNC:14864]",{"v":0.572691093333333,"d":"0.57"},{"v":0.214838736,"d":"0.21"},{"v":2.66567893665755,"d":"2.67"},{"v":1.41450302784425,"d":"1.41"},{"v":0.0945625510039658,"d":"0.09"},{"v":0.634846124908372,"d":"0.63"},"up","no"]
["MSTRG.10434","LGALS1","ENST00000215909;ENST00000425542;ENST00000454173;ENST00000472321;ENST00000480207;ENST00000464120;ENST00000489315","GO:0005615(extracellular space);GO:0003723(RNA binding);GO:0005737(cytoplasm);GO:0030246(carbohydrate binding);GO:0005515(protein binding);GO:0004871(signal transducer activity);GO:0005576(extracellular region);GO:0006915(apoptotic process);GO:0005578(proteinaceous extracellular matrix);GO:0007165(signal transduction);GO:0070062(extracellular exosome);GO:0044267(cellular protein metabolic process);GO:0043687(post-translational protein modification);GO:0031012(extracellular matrix);GO:0043123(positive regulation of I-kappaB kinase/NF-kappaB signaling);GO:0042981(regulation of apoptotic process);GO:0046598(positive regulation of viral entry into host cell);GO:0005788(endoplasmic reticulum lumen);GO:0005622(intracellular);GO:0030395(lactose binding);GO:0042803(protein homodimerization activity);GO:0043236(laminin binding);GO:0002317(plasma cell differentiation);GO:0010812(negative regulation of cell-substrate adhesion);GO:0010977(negative regulation of neuron projection development);GO:0031295(T cell costimulation);GO:0034120(positive regulation of erythrocyte aggregation);GO:0035900(response to isolation stress);GO:0042493(response to drug);GO:0045445(myoblast differentiation);GO:0048678(response to axon injury);GO:0071333(cellular response to glucose stimulus);GO:0071407(cellular response to organic cyclic compound);GO:0005634(nucleus);GO:0005829(cytosol);GO:0009986(cell surface);GO:0009986(cell surface)","NA","NA","NA","galectin 1 [Source:HGNC Symbol;Acc:HGNC:6561]",{"v":40.36416233394,"d":"40.36"},{"v":72.138325755232,"d":"72.14"},{"v":0.559538385613454,"d":"0.56"},{"v":-0.837690988110045,"d":"-0.84"},{"v":0.0945736498830176,"d":"0.09"},{"v":0.634846124908372,"d":"0.63"},"down","no"]
["MSTRG.11788","LEF1","MSTRG.11788.5;MSTRG.11788.7;MSTRG.11788.6;ENST00000265165;ENST00000514444;ENST00000505297;ENST00000506680;ENST00000512407;ENST00000509428;ENST00000512172;ENST00000507470;ENST00000505293;ENST00000438313;ENST00000510717;ENST00000505379;ENST00000510624;ENST00000504775;ENST00000510135;ENST00000379951;ENST00000503879;ENST00000504950;ENST00000504426;ENST00000515500","GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0005737(cytoplasm);GO:0005634(nucleus);GO:0008013(beta-catenin binding);GO:0006366(transcription from RNA polymerase II promoter);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0016055(Wnt signaling pathway);GO:0043401(steroid hormone mediated signaling pathway);GO:0045893(positive regulation of transcription, DNA-templated);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:0001077(transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0003682(chromatin binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0003705(transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding);GO:0008134(transcription factor binding);GO:0008301(DNA binding, bending);GO:0043565(sequence-specific DNA binding);GO:0044212(transcription regulatory region DNA binding);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0001569(branching involved in blood vessel morphogenesis);GO:0001756(somitogenesis);GO:0001837(epithelial to mesenchymal transition);GO:0001944(vasculature development);GO:0002040(sprouting angiogenesis);GO:0021542(dentate gyrus development);GO:0021766(hippocampus development);GO:0021861(forebrain radial glial cell differentiation);GO:0021873(forebrain neuroblast division);GO:0021943(formation of radial glial scaffolds);GO:0022407(regulation of cell-cell adhesion);GO:0030111(regulation of Wnt signaling pathway);GO:0030326(embryonic limb morphogenesis);GO:0030509(BMP signaling pathway);GO:0030879(mammary gland development);GO:0033153(T cell receptor V(D)J recombination);GO:0042100(B cell proliferation);GO:0042475(odontogenesis of dentin-containing tooth);GO:0043586(tongue development);GO:0045063(T-helper 1 cell differentiation);GO:0045843(negative regulation of striated muscle tissue development);GO:0045892(negative regulation of transcription, DNA-templated);GO:0046632(alpha-beta T cell differentiation);GO:0048341(paraxial mesoderm formation);GO:0048468(cell development);GO:0050909(sensory perception of taste);GO:0060021(palate development);GO:0060033(anatomical structure regression);GO:0060325(face morphogenesis);GO:0060561(apoptotic process involved in morphogenesis);GO:0060710(chorio-allantoic fusion);GO:0061153(trachea gland development);GO:1902262(apoptotic process involved in blood vessel morphogenesis);GO:0005667(transcription factor complex);GO:0005654(nucleoplasm);GO:0090090(negative regulation of canonical Wnt signaling pathway);GO:0030331(estrogen receptor binding);GO:0070016(armadillo repeat domain binding);GO:0030335(positive regulation of cell migration);GO:0010628(positive regulation of gene expression);GO:0008284(positive regulation of cell proliferation);GO:0030854(positive regulation of granulocyte differentiation);GO:0043066(negative regulation of apoptotic process);GO:0071345(cellular response to cytokine stimulus);GO:0042393(histone binding);GO:0043967(histone H4 acetylation);GO:1904837(beta-catenin-TCF complex assembly);GO:0010718(positive regulation of epithelial to mesenchymal transition);GO:0030307(positive regulation of cell growth);GO:0043154(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process);GO:0060326(cell chemotaxis);GO:0060070(canonical Wnt signaling pathway);GO:0000977(RNA polymerase II regulatory region sequence-specific DNA binding);GO:0043966(histone H3 acetylation);GO:0007223(Wnt signaling pathway, calcium modulating pathway);GO:0043027(cysteine-type endopeptidase inhibitor activity involved in apoptotic process);GO:0001649(osteoblast differentiation);GO:0042826(histone deacetylase binding);GO:0035326(enhancer binding);GO:0030284(estrogen receptor activity);GO:0001228(transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding);GO:0043392(negative regulation of DNA binding);GO:0043923(positive regulation by host of viral transcription);GO:0045295(gamma-catenin binding);GO:0032993(protein-DNA complex);GO:0071353(cellular response to interleukin-4);GO:0070742(C2H2 zinc finger domain binding);GO:1990907(beta-catenin-TCF complex);GO:0032696(negative regulation of interleukin-13 production);GO:0032714(negative regulation of interleukin-5 production);GO:0030223(neutrophil differentiation);GO:0071899(negative regulation of estrogen receptor binding);GO:0032713(negative regulation of interleukin-4 production);GO:0001755(neural crest cell migration);GO:0016202(regulation of striated muscle tissue development);GO:0021854(hypothalamus development);GO:0021879(forebrain neuron differentiation);GO:0048069(eye pigmentation);GO:0048747(muscle fiber development);GO:0071864(positive regulation of cell proliferation in bone marrow);GO:0071866(negative regulation of apoptotic process in bone marrow);GO:0071895(odontoblast differentiation);GO:0071895(odontoblast differentiation)","04310(Wnt signaling pathway);04390(Hippo signaling pathway);04520(Adherens junction);04916(Melanogenesis);05200(Pathways in cancer);05210(Colorectal cancer);05225(Hepatocellular carcinoma);05226(Gastric cancer);05216(Thyroid cancer);05221(Acute myeloid leukemia);05217(Basal cell carcinoma);05215(Prostate cancer);05213(Endometrial cancer);05224(Breast cancer);05412(Arrhythmogenic right ventricular cardiomyopathy (ARVC));05412(Arrhythmogenic right ventricular cardiomyopathy (ARVC))","K04492","NA","lymphoid enhancer binding factor 1 [Source:HGNC Symbol;Acc:HGNC:6551]",{"v":16.6719905236213,"d":"16.67"},{"v":6.41152824393749,"d":"6.41"},{"v":2.60031460352463,"d":"2.60"},{"v":1.3786861807488,"d":"1.38"},{"v":0.0946364924174518,"d":"0.09"},{"v":0.634900974259889,"d":"0.63"},"up","no"]
["MSTRG.8418","LILRA4;LILRA5;AC245884.11;VN1R104P;AC245884.6","ENST00000291759;ENST00000432233;ENST00000446712;ENST00000616950;ENST00000421056;ENST00000477720;ENST00000489504;ENST00000505115;ENST00000595581;ENST00000515672;ENST00000486742","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005515(protein binding);GO:0002376(immune system process);GO:0002250(adaptive immune response);GO:0005886(plasma membrane);GO:0005576(extracellular region);GO:0045087(innate immune response);GO:0070062(extracellular exosome);GO:0070062(extracellular exosome)","04380(Osteoclast differentiation);04380(Osteoclast differentiation)","K06512","NA","leukocyte immunoglobulin like receptor A4 [Source:HGNC Symbol;Acc:HGNC:15503];leukocyte immunoglobulin like receptor A5 [Source:HGNC Symbol;Acc:HGNC:16309];vomeronasal 1 receptor 104 pseudogene [Source:HGNC Symbol;Acc:HGNC:37427]",{"v":7.07385730992979,"d":"7.07"},{"v":12.6341558345035,"d":"12.63"},{"v":0.55989948221244,"d":"0.56"},{"v":-0.836760249020937,"d":"-0.84"},{"v":0.0949215139311511,"d":"0.09"},{"v":0.636445462634214,"d":"0.64"},"down","no"]
["MSTRG.9440","DNPEP","ENST00000373966;ENST00000273075;ENST00000519698;ENST00000488051;ENST00000488881;ENST00000523282;ENST00000522421;ENST00000462779;ENST00000520694;ENST00000523527;ENST00000434339;ENST00000373963;ENST00000373972;ENST00000460963;ENST00000457935;ENST00000322176;ENST00000521459;ENST00000430206;ENST00000490371","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0005829(cytosol);GO:0016787(hydrolase activity);GO:0005515(protein binding);GO:0008233(peptidase activity);GO:0006508(proteolysis);GO:0008237(metallopeptidase activity);GO:0004177(aminopeptidase activity);GO:0042802(identical protein binding);GO:0072562(blood microparticle);GO:0070006(metalloaminopeptidase activity);GO:0006518(peptide metabolic process);GO:0006518(peptide metabolic process)","NA","NA","NA","aspartyl aminopeptidase [Source:HGNC Symbol;Acc:HGNC:2981]",{"v":2.80550894824673,"d":"2.81"},{"v":5.02141437874947,"d":"5.02"},{"v":0.558708908812543,"d":"0.56"},{"v":-0.83983127012575,"d":"-0.84"},{"v":0.095145374342442,"d":"0.10"},{"v":0.637319956220937,"d":"0.64"},"down","no"]
["MSTRG.8275","SELENOW","ENST00000612212;ENST00000601048;ENST00000598273;ENST00000601419;ENST00000598956;ENST00000595615;ENST00000602163;ENST00000601937;ENST00000598083;ENST00000599302;ENST00000593892;ENST00000599627;ENST00000599874","GO:0005737(cytoplasm);GO:0098869(cellular oxidant detoxification);GO:0016209(antioxidant activity);GO:0016209(antioxidant activity)","NA","NA","NA","selenoprotein W [Source:HGNC Symbol;Acc:HGNC:10752]",{"v":4.06359577931952,"d":"4.06"},{"v":7.26809568789204,"d":"7.27"},{"v":0.559100478835066,"d":"0.56"},{"v":-0.838820514340363,"d":"-0.84"},{"v":0.0952038502907569,"d":"0.10"},{"v":0.637319956220937,"d":"0.64"},"down","no"]
["MSTRG.3341","CCDC65","ENST00000552188;ENST00000266984;ENST00000320516","NA","NA","NA","NA","coiled-coil domain containing 65 [Source:HGNC Symbol;Acc:HGNC:29937]",{"v":1.72221114369996,"d":"1.72"},{"v":3.10842063674673,"d":"3.11"},{"v":0.554047004881046,"d":"0.55"},{"v":-0.851919716388941,"d":"-0.85"},{"v":0.0952176363939815,"d":"0.10"},{"v":0.637319956220937,"d":"0.64"},"down","no"]
["MSTRG.13513","RPL21P75","ENST00000396599","NA","NA","NA","NA","ribosomal protein L21 pseudogene 75 [Source:HGNC Symbol;Acc:HGNC:36460]",{"v":195.895432,"d":"195.90"},{"v":349.241852,"d":"349.24"},{"v":0.560916255821482,"d":"0.56"},{"v":-0.834142700754807,"d":"-0.83"},{"v":0.0952714581933649,"d":"0.10"},{"v":0.637319956220937,"d":"0.64"},"down","no"]
["MSTRG.9243","OLA1","ENST00000284719;ENST00000428402;ENST00000344357;ENST00000497760;ENST00000429575;ENST00000462000;ENST00000392560;ENST00000409546","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005525(GTP binding);GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0005829(cytosol);GO:0016787(hydrolase activity);GO:0005813(centrosome);GO:0005515(protein binding);GO:0005730(nucleolus);GO:0005576(extracellular region);GO:0045296(cadherin binding);GO:0070062(extracellular exosome);GO:0002576(platelet degranulation);GO:0031093(platelet alpha granule lumen);GO:0016887(ATPase activity);GO:0046034(ATP metabolic process);GO:0043022(ribosome binding);GO:0043023(ribosomal large subunit binding);GO:0043023(ribosomal large subunit binding)","NA","NA","NA","Obg like ATPase 1 [Source:HGNC Symbol;Acc:HGNC:28833]",{"v":3.01081603983607,"d":"3.01"},{"v":5.38211628229508,"d":"5.38"},{"v":0.559411183615709,"d":"0.56"},{"v":-0.838018998767854,"d":"-0.84"},{"v":0.0954168051454538,"d":"0.10"},{"v":0.63758059297343,"d":"0.64"},"down","no"]
["MSTRG.7635","SF3A2","ENST00000221494;ENST00000587637;ENST00000590034;ENST00000586396;ENST00000592314;ENST00000592839","GO:0005634(nucleus);GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0006397(mRNA processing);GO:0008380(RNA splicing);GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0005515(protein binding);GO:0005681(spliceosomal complex);GO:0005654(nucleoplasm);GO:0000398(mRNA splicing, via spliceosome);GO:0071013(catalytic step 2 spliceosome);GO:0005686(U2 snRNP);GO:0071004(U2-type prespliceosome);GO:0000389(mRNA 3'-splice site recognition);GO:0030532(small nuclear ribonucleoprotein complex);GO:0010976(positive regulation of neuron projection development);GO:0016607(nuclear speck);GO:0016607(nuclear speck)","03040(Spliceosome);03040(Spliceosome)","K12826","NA","splicing factor 3a subunit 2 [Source:HGNC Symbol;Acc:HGNC:10766]",{"v":8.41948292342055,"d":"8.42"},{"v":3.23940470006382,"d":"3.24"},{"v":2.59908338197283,"d":"2.60"},{"v":1.37800291808448,"d":"1.38"},{"v":0.09548179527577,"d":"0.10"},{"v":0.63758059297343,"d":"0.64"},"up","no"]
["ENSG00000156453","PCDH1","ENST00000287008;ENST00000511044;ENST00000515351;ENST00000357517;ENST00000394536","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0043231(intracellular membrane-bounded organelle);GO:0005634(nucleus);GO:0005730(nucleolus);GO:0005509(calcium ion binding);GO:0007155(cell adhesion);GO:0007156(homophilic cell adhesion via plasma membrane adhesion molecules);GO:0005886(plasma membrane);GO:0030054(cell junction);GO:0005887(integral component of plasma membrane);GO:0007399(nervous system development);GO:0007267(cell-cell signaling);GO:0005911(cell-cell junction);GO:0005911(cell-cell junction)","NA","NA","NA","protocadherin 1 [Source:HGNC Symbol;Acc:HGNC:8655]",{"v":0.885367355581908,"d":"0.89"},{"v":0.335385561917669,"d":"0.34"},{"v":2.63984934390005,"d":"2.64"},{"v":1.40045559738287,"d":"1.40"},{"v":0.0954879256153012,"d":"0.10"},{"v":0.63758059297343,"d":"0.64"},"up","no"]
["MSTRG.5381","RPS17;AC245033.1;CPEB1","ENST00000561157;ENST00000560612;ENST00000330244;ENST00000560229;ENST00000559776;ENST00000559273;ENST00000562833;ENST00000561068;ENST00000614918;ENST00000561440;ENST00000570205;ENST00000560639;ENST00000558397","GO:0003723(RNA binding);GO:0016020(membrane);GO:0006412(translation);GO:0006413(translational initiation);GO:0030529(intracellular ribonucleoprotein complex);GO:0005622(intracellular);GO:0003735(structural constituent of ribosome);GO:0005840(ribosome);GO:0022627(cytosolic small ribosomal subunit);GO:0005925(focal adhesion);GO:0006364(rRNA processing);GO:0042274(ribosomal small subunit biogenesis);GO:0000028(ribosomal small subunit assembly);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0031012(extracellular matrix);GO:0000184(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay);GO:0019083(viral transcription);GO:0006614(SRP-dependent cotranslational protein targeting to membrane);GO:0034101(erythrocyte homeostasis);GO:0003676(nucleic acid binding);GO:0003730(mRNA 3'-UTR binding);GO:0045182(translation regulator activity);GO:0006417(regulation of translation);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0045202(synapse);GO:0000900(translation repressor activity, nucleic acid binding);GO:0008135(translation factor activity, RNA binding);GO:0043022(ribosome binding);GO:2000766(negative regulation of cytoplasmic translation);GO:0043005(neuron projection);GO:1990124(messenger ribonucleoprotein complex);GO:0006397(mRNA processing);GO:0046872(metal ion binding);GO:0005886(plasma membrane);GO:0042995(cell projection);GO:0030054(cell junction);GO:0045211(postsynaptic membrane);GO:0030425(dendrite);GO:0000932(P-body);GO:0071230(cellular response to amino acid stimulus);GO:0014069(postsynaptic density);GO:0032869(cellular response to insulin stimulus);GO:0071456(cellular response to hypoxia);GO:0035925(mRNA 3'-UTR AU-rich region binding);GO:0008285(negative regulation of cell proliferation);GO:0010976(positive regulation of neuron projection development);GO:0017148(negative regulation of translation);GO:0030335(positive regulation of cell migration);GO:0045727(positive regulation of translation);GO:0051028(mRNA transport);GO:0051770(positive regulation of nitric-oxide synthase biosynthetic process);GO:0071222(cellular response to lipopolysaccharide);GO:0005813(centrosome);GO:0030426(growth cone);GO:0043025(neuronal cell body);GO:0048471(perinuclear region of cytoplasm);GO:0034101(erythrocyte homeostasis)","03010(Ribosome);04114(Oocyte meiosis);04914(Progesterone-mediated oocyte maturation);03010(Ribosome)","K02962","NA","ribosomal protein S17 [Source:HGNC Symbol;Acc:HGNC:10397];cytoplasmic polyadenylation element binding protein 1 [Source:HGNC Symbol;Acc:HGNC:21744]",{"v":16.9408003412322,"d":"16.94"},{"v":30.1824283834705,"d":"30.18"},{"v":0.561280229874077,"d":"0.56"},{"v":-0.833206851131682,"d":"-0.83"},{"v":0.0955300294302737,"d":"0.10"},{"v":0.63758059297343,"d":"0.64"},"down","no"]
["MSTRG.7292","TIMP2;CEP295NL","ENST00000262768;ENST00000592761;ENST00000586713;ENST00000322630;ENST00000536189;ENST00000586057","GO:0005576(extracellular region);GO:0008191(metalloendopeptidase inhibitor activity);GO:0010951(negative regulation of endopeptidase activity);GO:0046872(metal ion binding);GO:0008270(zinc ion binding);GO:0005515(protein binding);GO:0005615(extracellular space);GO:0030414(peptidase inhibitor activity);GO:0010466(negative regulation of peptidase activity);GO:0005178(integrin binding);GO:0007417(central nervous system development);GO:0007568(aging);GO:0008285(negative regulation of cell proliferation);GO:0032487(regulation of Rap protein signal transduction);GO:0034097(response to cytokine);GO:0042493(response to drug);GO:0043410(positive regulation of MAPK cascade);GO:0045666(positive regulation of neuron differentiation);GO:0045762(positive regulation of adenylate cyclase activity);GO:0045861(negative regulation of proteolysis);GO:0045930(negative regulation of mitotic cell cycle);GO:0046580(negative regulation of Ras protein signal transduction);GO:0009986(cell surface);GO:0030426(growth cone);GO:0043005(neuron projection);GO:0043025(neuronal cell body);GO:0070062(extracellular exosome);GO:0031012(extracellular matrix);GO:0043312(neutrophil degranulation);GO:0005578(proteinaceous extracellular matrix);GO:0002020(protease binding);GO:1904813(ficolin-1-rich granule lumen);GO:0035580(specific granule lumen);GO:1904724(tertiary granule lumen);GO:0022617(extracellular matrix disassembly);GO:0004857(enzyme inhibitor activity);GO:0009725(response to hormone);GO:1905049(negative regulation of metallopeptidase activity);GO:0051045(negative regulation of membrane protein ectodomain proteolysis);GO:0042995(cell projection);GO:0005929(cilium);GO:0031514(motile cilium);GO:0051045(negative regulation of membrane protein ectodomain proteolysis)","NA","NA","NA","TIMP metallopeptidase inhibitor 2 [Source:HGNC Symbol;Acc:HGNC:11821];CEP295 N-terminal like [Source:HGNC Symbol;Acc:HGNC:44659]",{"v":15.2777043550592,"d":"15.28"},{"v":5.90110085267912,"d":"5.90"},{"v":2.58895835479969,"d":"2.59"},{"v":1.37237175866901,"d":"1.37"},{"v":0.095596966782959,"d":"0.10"},{"v":0.637660870333431,"d":"0.64"},"up","no"]
["MSTRG.12625","RACK1","ENST00000508682;ENST00000513060;ENST00000504325;ENST00000513027;ENST00000514455;ENST00000502905;ENST00000514183;ENST00000512805;ENST00000509148;ENST00000511473;ENST00000509535;ENST00000502890;ENST00000502844;ENST00000504726;ENST00000508044;ENST00000507261;ENST00000510199;ENST00000503081;ENST00000507000;ENST00000511900;ENST00000515417;ENST00000376817;ENST00000507756;ENST00000507273;ENST00000514318;ENST00000512968;ENST00000511566;ENST00000504128;ENST00000505461;ENST00000508963;ENST00000502548;ENST00000503494;ENST00000506312;ENST00000626067","GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0016567(protein ubiquitination);GO:0030529(intracellular ribonucleoprotein complex);GO:0005840(ribosome);GO:0005739(mitochondrion);GO:0005886(plasma membrane);GO:0042995(cell projection);GO:0005515(protein binding);GO:0007049(cell cycle);GO:0048511(rhythmic process);GO:0006915(apoptotic process);GO:0007275(multicellular organism development);GO:0048471(perinuclear region of cytoplasm);GO:0065009(regulation of molecular function);GO:0043022(ribosome binding);GO:0030425(dendrite);GO:0030496(midbody);GO:0045296(cadherin binding);GO:2000114(regulation of establishment of cell polarity);GO:0043204(perikaryon);GO:0070062(extracellular exosome);GO:0001934(positive regulation of protein phosphorylation);GO:0001891(phagocytic cup);GO:0043547(positive regulation of GTPase activity);GO:0042169(SH2 domain binding);GO:0040008(regulation of growth);GO:0032947(protein complex scaffold);GO:0006417(regulation of translation);GO:0030178(negative regulation of Wnt signaling pathway);GO:0030335(positive regulation of cell migration);GO:0043065(positive regulation of apoptotic process);GO:0016032(viral process);GO:0005102(receptor binding);GO:0017148(negative regulation of translation);GO:0008200(ion channel inhibitor activity);GO:0006412(translation);GO:0043473(pigmentation);GO:1903208(negative regulation of hydrogen peroxide-induced neuron death);GO:0043005(neuron projection);GO:0043025(neuronal cell body);GO:0044297(cell body);GO:0010629(negative regulation of gene expression);GO:0019903(protein phosphatase binding);GO:0030308(negative regulation of cell growth);GO:0042803(protein homodimerization activity);GO:0051726(regulation of cell cycle);GO:2001244(positive regulation of intrinsic apoptotic signaling pathway);GO:0030971(receptor tyrosine kinase binding);GO:0051302(regulation of cell division);GO:0019899(enzyme binding);GO:0008656(cysteine-type endopeptidase activator activity involved in apoptotic process);GO:0006919(activation of cysteine-type endopeptidase activity involved in apoptotic process);GO:0051898(negative regulation of protein kinase B signaling);GO:0071333(cellular response to glucose stimulus);GO:0010803(regulation of tumor necrosis factor-mediated signaling pathway);GO:0071363(cellular response to growth factor stimulus);GO:0032880(regulation of protein localization);GO:0033137(negative regulation of peptidyl-serine phosphorylation);GO:0050765(negative regulation of phagocytosis);GO:2000304(positive regulation of ceramide biosynthetic process);GO:0032436(positive regulation of proteasomal ubiquitin-dependent protein catabolic process);GO:1990630(IRE1-RACK1-PP2A complex);GO:0030822(positive regulation of cAMP catabolic process);GO:0042998(positive regulation of Golgi to plasma membrane protein transport);GO:0030292(protein tyrosine kinase inhibitor activity);GO:0061099(negative regulation of protein tyrosine kinase activity);GO:0007369(gastrulation);GO:0005080(protein kinase C binding);GO:0032464(positive regulation of protein homooligomerization);GO:2000543(positive regulation of gastrulation);GO:0015935(small ribosomal subunit);GO:0035591(signaling adaptor activity);GO:0051343(positive regulation of cyclic-nucleotide phosphodiesterase activity);GO:0051901(positive regulation of mitochondrial depolarization);GO:0072344(rescue of stalled ribosome);GO:1900102(negative regulation of endoplasmic reticulum unfolded protein response);GO:1900102(negative regulation of endoplasmic reticulum unfolded protein response)","05162(Measles);05162(Measles)","K14753","NA","receptor for activated C kinase 1 [Source:HGNC Symbol;Acc:HGNC:4399]",{"v":95.2752287425709,"d":"95.28"},{"v":169.643270250751,"d":"169.64"},{"v":0.56162103337046,"d":"0.56"},{"v":-0.832331127601326,"d":"-0.83"},{"v":0.0956743871912704,"d":"0.10"},{"v":0.637810940558107,"d":"0.64"},"down","no"]
["MSTRG.2889","BACE1","ENST00000313005;ENST00000445823;ENST00000513780;ENST00000509916;ENST00000530824","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016787(hydrolase activity);GO:0005794(Golgi apparatus);GO:0005783(endoplasmic reticulum);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0008233(peptidase activity);GO:0006508(proteolysis);GO:0004190(aspartic-type endopeptidase activity);GO:0004175(endopeptidase activity);GO:0050435(amyloid-beta metabolic process);GO:0050804(modulation of synaptic transmission);GO:0005768(endosome);GO:0005802(trans-Golgi network);GO:0030424(axon);GO:0031410(cytoplasmic vesicle);GO:0030659(cytoplasmic vesicle membrane);GO:0045121(membrane raft);GO:0005887(integral component of plasma membrane);GO:0044267(cellular protein metabolic process);GO:0010008(endosome membrane);GO:0005770(late endosome);GO:0030163(protein catabolic process);GO:0019899(enzyme binding);GO:0009986(cell surface);GO:0005788(endoplasmic reticulum lumen);GO:0006509(membrane protein ectodomain proteolysis);GO:0005771(multivesicular body);GO:0001540(amyloid-beta binding);GO:0008798(beta-aspartyl-peptidase activity);GO:0070931(Golgi-associated vesicle lumen);GO:0070931(Golgi-associated vesicle lumen)","05010(Alzheimer's disease);05010(Alzheimer's disease)","K04521","EC:3.4.23.46","beta-secretase 1 [Source:HGNC Symbol;Acc:HGNC:933]",{"v":0.879719592906815,"d":"0.88"},{"v":0.333833713351878,"d":"0.33"},{"v":2.63520296998747,"d":"2.64"},{"v":1.39791408615739,"d":"1.40"},{"v":0.095752666407922,"d":"0.10"},{"v":0.637966560525071,"d":"0.64"},"up","no"]
["MSTRG.11146","MYLK","MSTRG.11146.1","NA","NA","NA","NA",null,{"v":2.284067,"d":"2.28"},{"v":4.255288,"d":"4.26"},{"v":0.536759674080814,"d":"0.54"},{"v":-0.897651806711757,"d":"-0.90"},{"v":0.095904010058616,"d":"0.10"},{"v":0.638569056258197,"d":"0.64"},"down","no"]
["ENSG00000204120","GIGYF2","ENST00000373563;ENST00000409547;ENST00000445650;ENST00000424414;ENST00000488734;ENST00000424038;ENST00000436349;ENST00000476995;ENST00000429187;ENST00000469843;ENST00000427233;ENST00000492910;ENST00000409196;ENST00000463554;ENST00000489328;ENST00000430720;ENST00000410033;ENST00000464805;ENST00000475359;ENST00000474465;ENST00000474312;ENST00000488629;ENST00000456491;ENST00000440945;ENST00000490612;ENST00000464402;ENST00000483164;ENST00000409451;ENST00000482666;ENST00000423659;ENST00000421433;ENST00000425040;ENST00000629305;ENST00000490229","GO:0003723(RNA binding);GO:0016020(membrane);GO:0005829(cytosol);GO:0005515(protein binding);GO:0005783(endoplasmic reticulum);GO:0045296(cadherin binding);GO:0043234(protein complex);GO:0005794(Golgi apparatus);GO:0017148(negative regulation of translation);GO:0005768(endosome);GO:0070064(proline-rich region binding);GO:0016441(posttranscriptional gene silencing);GO:0048009(insulin-like growth factor receptor signaling pathway);GO:0061157(mRNA destabilization);GO:0010494(cytoplasmic stress granule);GO:0043204(perikaryon);GO:1990635(proximal dendrite);GO:0007631(feeding behavior);GO:0008344(adult locomotory behavior);GO:0009791(post-embryonic development);GO:0021522(spinal cord motor neuron differentiation);GO:0031571(mitotic G1 DNA damage checkpoint);GO:0035264(multicellular organism growth);GO:0044267(cellular protein metabolic process);GO:0048873(homeostasis of number of cells within a tissue);GO:0050881(musculoskeletal movement);GO:0050885(neuromuscular process controlling balance);GO:0005737(cytoplasm);GO:0016021(integral component of membrane);GO:0031982(vesicle);GO:0031982(vesicle)","NA","NA","NA","GRB10 interacting GYF protein 2 [Source:HGNC Symbol;Acc:HGNC:11960]",{"v":3.40490459287418,"d":"3.40"},{"v":1.31211225298151,"d":"1.31"},{"v":2.59497964837781,"d":"2.59"},{"v":1.37572322401686,"d":"1.38"},{"v":0.095988934188612,"d":"0.10"},{"v":0.638569056258197,"d":"0.64"},"up","no"]
["MSTRG.11139","PARP14","ENST00000474629;ENST00000474669;ENST00000460683;ENST00000494811","GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005829(cytosol);GO:0016740(transferase activity);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0016757(transferase activity, transferring glycosyl groups);GO:0003950(NAD+ ADP-ribosyltransferase activity);GO:0005515(protein binding);GO:0005515(protein binding)","NA","NA","NA","poly(ADP-ribose) polymerase family member 14 [Source:HGNC Symbol;Acc:HGNC:29232]",{"v":12.5943700231539,"d":"12.59"},{"v":4.86862259790376,"d":"4.87"},{"v":2.58684458897606,"d":"2.59"},{"v":1.37119338318832,"d":"1.37"},{"v":0.0960080575412738,"d":"0.10"},{"v":0.638569056258197,"d":"0.64"},"up","no"]
["MSTRG.3457","NABP2","ENST00000267023;ENST00000380198;ENST00000447747;ENST00000341463;ENST00000479016;ENST00000399713","GO:0003676(nucleic acid binding);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0006281(DNA repair);GO:0007093(mitotic cell cycle checkpoint);GO:0070876(SOSS complex);GO:0005634(nucleus);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0006974(cellular response to DNA damage stimulus);GO:0000784(nuclear chromosome, telomeric region);GO:0042795(snRNA transcription from RNA polymerase II promoter);GO:0000724(double-strand break repair via homologous recombination);GO:1904355(positive regulation of telomere capping);GO:0070200(establishment of protein localization to telomere);GO:0003697(single-stranded DNA binding);GO:0010212(response to ionizing radiation);GO:0070182(DNA polymerase binding);GO:0098505(G-rich strand telomeric DNA binding);GO:0098505(G-rich strand telomeric DNA binding)","NA","NA","NA","nucleic acid binding protein 2 [Source:HGNC Symbol;Acc:HGNC:28412]",{"v":2.33983742605951,"d":"2.34"},{"v":4.2189974657349,"d":"4.22"},{"v":0.554595598850861,"d":"0.55"},{"v":-0.850491927376238,"d":"-0.85"},{"v":0.0961866158402706,"d":"0.10"},{"v":0.639390480682921,"d":"0.64"},"down","no"]
["MSTRG.2523","EHD1","ENST00000320631;ENST00000621096;ENST00000455148;ENST00000457202;ENST00000488711;ENST00000359393;ENST00000421510;ENST00000466015;ENST00000498472;ENST00000433803;ENST00000411683;ENST00000484846","GO:0042632(cholesterol homeostasis);GO:0006810(transport);GO:0016020(membrane);GO:0015031(protein transport);GO:0005525(GTP binding);GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0005509(calcium ion binding);GO:0005886(plasma membrane);GO:0042995(cell projection);GO:0005515(protein binding);GO:0006886(intracellular protein transport);GO:0042802(identical protein binding);GO:0005768(endosome);GO:0060271(cilium assembly);GO:0005929(cilium);GO:0045296(cadherin binding);GO:0006897(endocytosis);GO:0070062(extracellular exosome);GO:0030030(cell projection organization);GO:0010008(endosome membrane);GO:0031901(early endosome membrane);GO:0055038(recycling endosome membrane);GO:0060170(ciliary membrane);GO:1901741(positive regulation of myoblast fusion);GO:0031175(neuron projection development);GO:0007596(blood coagulation);GO:0051260(protein homooligomerization);GO:0017137(Rab GTPase binding);GO:0005811(lipid particle);GO:0032456(endocytic recycling);GO:0020018(ciliary pocket membrane);GO:0034383(low-density lipoprotein particle clearance);GO:0010886(positive regulation of cholesterol storage);GO:1990090(cellular response to nerve growth factor stimulus);GO:2001137(positive regulation of endocytic recycling);GO:0061512(protein localization to cilium);GO:0031095(platelet dense tubular network membrane);GO:0016197(endosomal transport);GO:0005769(early endosome);GO:0030139(endocytic vesicle);GO:0043209(myelin sheath);GO:0048471(perinuclear region of cytoplasm);GO:0048471(perinuclear region of cytoplasm)","04144(Endocytosis);04144(Endocytosis)","K12483","NA","EH domain containing 1 [Source:HGNC Symbol;Acc:HGNC:3242]",{"v":26.0036386638502,"d":"26.00"},{"v":10.0635718172088,"d":"10.06"},{"v":2.58393730736673,"d":"2.58"},{"v":1.36957106714935,"d":"1.37"},{"v":0.096265626930402,"d":"0.10"},{"v":0.639549614154896,"d":"0.64"},"up","no"]
["MSTRG.1896","EXOSC1","ENST00000370902;ENST00000370885;ENST00000471049;ENST00000477692;ENST00000476234;ENST00000489158","GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005515(protein binding);GO:0005730(nucleolus);GO:0006364(rRNA processing);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0000178(exosome (RNase complex));GO:0043488(regulation of mRNA stability);GO:0043928(exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay);GO:0000176(nuclear exosome (RNase complex));GO:0000176(nuclear exosome (RNase complex))","03018(RNA degradation);03018(RNA degradation)","K07573","NA","exosome component 1 [Source:HGNC Symbol;Acc:HGNC:17286]",{"v":1.95511094080717,"d":"1.96"},{"v":3.50232385022422,"d":"3.50"},{"v":0.558232483464373,"d":"0.56"},{"v":-0.841062017833009,"d":"-0.84"},{"v":0.0963738458040618,"d":"0.10"},{"v":0.639902499326798,"d":"0.64"},"down","no"]
["MSTRG.5386","SEC11A","ENST00000268220;ENST00000455959;ENST00000558924;ENST00000558134;ENST00000558217;ENST00000558196;ENST00000560409;ENST00000559729;ENST00000560266;ENST00000559376","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016787(hydrolase activity);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0008233(peptidase activity);GO:0006508(proteolysis);GO:0008236(serine-type peptidase activity);GO:0006465(signal peptide processing);GO:0043231(intracellular membrane-bounded organelle);GO:0070062(extracellular exosome);GO:0031090(organelle membrane);GO:0005787(signal peptidase complex);GO:0005787(signal peptidase complex)","03060(Protein export);03060(Protein export)","K13280","EC:3.4.21.89","SEC11 homolog A, signal peptidase complex subunit [Source:HGNC Symbol;Acc:HGNC:17718]",{"v":4.47604951113431,"d":"4.48"},{"v":7.97260443145442,"d":"7.97"},{"v":0.561428771440722,"d":"0.56"},{"v":-0.832825095605427,"d":"-0.83"},{"v":0.0964870727827302,"d":"0.10"},{"v":0.640093278656057,"d":"0.64"},"down","no"]
["MSTRG.3606","UBE2N","ENST00000318066;ENST00000550657;ENST00000549833;ENST00000549490;ENST00000552442","GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0016740(transferase activity);GO:0016567(protein ubiquitination);GO:0001650(fibrillar center);GO:0005515(protein binding);GO:0006281(DNA repair);GO:0006974(cellular response to DNA damage stimulus);GO:0038095(Fc-epsilon receptor signaling pathway);GO:0031625(ubiquitin protein ligase binding);GO:0061630(ubiquitin protein ligase activity);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0002223(stimulatory C-type lectin receptor signaling pathway);GO:0050852(T cell receptor signaling pathway);GO:0043234(protein complex);GO:0051092(positive regulation of NF-kappaB transcription factor activity);GO:0004842(ubiquitin-protein transferase activity);GO:0006464(cellular protein modification process);GO:0070534(protein K63-linked ubiquitination);GO:0000151(ubiquitin ligase complex);GO:0007254(JNK cascade);GO:0043123(positive regulation of I-kappaB kinase/NF-kappaB signaling);GO:0070423(nucleotide-binding oligomerization domain containing signaling pathway);GO:0000187(activation of MAPK activity);GO:0006508(proteolysis);GO:0006303(double-strand break repair via nonhomologous end joining);GO:0043130(ubiquitin binding);GO:0070911(global genome nucleotide-excision repair);GO:0000724(double-strand break repair via homologous recombination);GO:0006301(postreplication repair);GO:0061631(ubiquitin conjugating enzyme activity);GO:0000729(DNA double-strand break processing);GO:0006282(regulation of DNA repair);GO:0006511(ubiquitin-dependent protein catabolic process);GO:0016574(histone ubiquitination);GO:0031058(positive regulation of histone modification);GO:0033182(regulation of histone ubiquitination);GO:0045739(positive regulation of DNA repair);GO:0051443(positive regulation of ubiquitin-protein transferase activity);GO:0031372(UBC13-MMS2 complex);GO:0035370(UBC13-UEV1A complex);GO:0035370(UBC13-UEV1A complex)","04120(Ubiquitin mediated proteolysis);04120(Ubiquitin mediated proteolysis)","K10580","EC:2.3.2.23","ubiquitin conjugating enzyme E2 N [Source:HGNC Symbol;Acc:HGNC:12492]",{"v":4.98621534614771,"d":"4.99"},{"v":8.87606466693252,"d":"8.88"},{"v":0.561759691175267,"d":"0.56"},{"v":-0.831974986670614,"d":"-0.83"},{"v":0.0966027320158384,"d":"0.10"},{"v":0.640093278656057,"d":"0.64"},"down","no"]
["MSTRG.159","MAD2L2","ENST00000376692;ENST00000376672;ENST00000376655;ENST00000445656;ENST00000376669;ENST00000376667;ENST00000376664;ENST00000456915","GO:0043433(negative regulation of sequence-specific DNA binding transcription factor activity);GO:0090090(negative regulation of canonical Wnt signaling pathway);GO:0010719(negative regulation of epithelial to mesenchymal transition);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005730(nucleolus);GO:0005829(cytosol);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0051301(cell division);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0006281(DNA repair);GO:0006974(cellular response to DNA damage stimulus);GO:0007049(cell cycle);GO:0045893(positive regulation of transcription, DNA-templated);GO:0005819(spindle);GO:0005654(nucleoplasm);GO:0033138(positive regulation of peptidyl-serine phosphorylation);GO:0001558(regulation of cell growth);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0005680(anaphase-promoting complex);GO:0001102(RNA polymerase II activating transcription factor binding);GO:0042177(negative regulation of protein catabolic process);GO:0010944(negative regulation of transcription by competitive promoter binding);GO:0007094(mitotic spindle assembly checkpoint);GO:0042276(error-prone translesion synthesis);GO:0016035(zeta DNA polymerase complex);GO:0006302(double-strand break repair);GO:2000048(negative regulation of cell-cell adhesion mediated by cadherin);GO:0007015(actin filament organization);GO:2000678(negative regulation of transcription regulatory region DNA binding);GO:1904667(negative regulation of ubiquitin protein ligase activity);GO:0008432(JUN kinase binding);GO:0042772(DNA damage response, signal transduction resulting in transcription);GO:0042772(DNA damage response, signal transduction resulting in transcription)","04110(Cell cycle);04114(Oocyte meiosis);04914(Progesterone-mediated oocyte maturation);05131(Shigellosis);05100(Bacterial invasion of epithelial cells);05100(Bacterial invasion of epithelial cells)","K13728","NA","mitotic arrest deficient 2 like 2 [Source:HGNC Symbol;Acc:HGNC:6764]",{"v":2.82897789290012,"d":"2.83"},{"v":5.05242077196149,"d":"5.05"},{"v":0.559925235958096,"d":"0.56"},{"v":-0.83669389077657,"d":"-0.84"},{"v":0.0966205543109646,"d":"0.10"},{"v":0.640093278656057,"d":"0.64"},"down","no"]
["ENSG00000125629","INSIG2","ENST00000614681;ENST00000479999;ENST00000485520;ENST00000488995;ENST00000245787","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0006629(lipid metabolic process);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0008202(steroid metabolic process);GO:0005515(protein binding);GO:0008134(transcription factor binding);GO:0006641(triglyceride metabolic process);GO:0006695(cholesterol biosynthetic process);GO:0006991(response to sterol depletion);GO:0008203(cholesterol metabolic process);GO:0010894(negative regulation of steroid biosynthetic process);GO:0016126(sterol biosynthetic process);GO:0032868(response to insulin);GO:0033993(response to lipid);GO:0042472(inner ear morphogenesis);GO:0042474(middle ear morphogenesis);GO:0045717(negative regulation of fatty acid biosynthetic process);GO:0060021(palate development);GO:0060363(cranial suture morphogenesis);GO:0070542(response to fatty acid);GO:0032933(SREBP signaling pathway);GO:0032937(SREBP-SCAP-Insig complex);GO:0032937(SREBP-SCAP-Insig complex)","NA","NA","NA","insulin induced gene 2 [Source:HGNC Symbol;Acc:HGNC:20452]",{"v":0.528543247594937,"d":"0.53"},{"v":0.960962894936709,"d":"0.96"},{"v":0.550014210100951,"d":"0.55"},{"v":-0.862459202473081,"d":"-0.86"},{"v":0.0966760268051844,"d":"0.10"},{"v":0.640093278656057,"d":"0.64"},"down","no"]
["MSTRG.14002","ZC3HAV1","ENST00000464606;ENST00000471652;ENST00000242351;ENST00000460845","GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0005829(cytosol);GO:0005515(protein binding);GO:0002376(immune system process);GO:0045087(innate immune response);GO:0051607(defense response to virus);GO:0045296(cadherin binding);GO:0009615(response to virus);GO:0045071(negative regulation of viral genome replication);GO:0061014(positive regulation of mRNA catabolic process);GO:0003950(NAD+ ADP-ribosyltransferase activity);GO:0003950(NAD+ ADP-ribosyltransferase activity)","NA","NA","NA","zinc finger CCCH-type containing, antiviral 1 [Source:HGNC Symbol;Acc:HGNC:23721]",{"v":14.6808435497268,"d":"14.68"},{"v":5.68506532386157,"d":"5.69"},{"v":2.58235265795589,"d":"2.58"},{"v":1.3686860351695,"d":"1.37"},{"v":0.0967442735428402,"d":"0.10"},{"v":0.640093278656057,"d":"0.64"},"up","no"]
["MSTRG.5445","SLCO3A1","ENST00000318445;ENST00000424469;ENST00000566477;ENST00000555769;ENST00000555892;ENST00000555549;ENST00000555111;ENST00000556649;ENST00000555513;ENST00000553653;ENST00000555210;ENST00000564072;ENST00000553304","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005215(transporter activity);GO:0006811(ion transport);GO:0005886(plasma membrane);GO:0015347(sodium-independent organic anion transmembrane transporter activity);GO:0043252(sodium-independent organic anion transport);GO:0005887(integral component of plasma membrane);GO:0015732(prostaglandin transport);GO:0015732(prostaglandin transport)","NA","NA","NA","solute carrier organic anion transporter family member 3A1 [Source:HGNC Symbol;Acc:HGNC:10952]",{"v":5.62672209231585,"d":"5.63"},{"v":2.17262044133545,"d":"2.17"},{"v":2.58983206880685,"d":"2.59"},{"v":1.37285855298743,"d":"1.37"},{"v":0.0967812630501054,"d":"0.10"},{"v":0.640093278656057,"d":"0.64"},"up","no"]
["MSTRG.7597","SBNO2","ENST00000361757;ENST00000438103;ENST00000587673;ENST00000586109;ENST00000590998;ENST00000587024;ENST00000587655;ENST00000590176;ENST00000592222;ENST00000590446","GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0030154(cell differentiation);GO:0050727(regulation of inflammatory response);GO:0005575(cellular_component);GO:0071222(cellular response to lipopolysaccharide);GO:0001503(ossification);GO:0045892(negative regulation of transcription, DNA-templated);GO:0071354(cellular response to interleukin-6);GO:0002281(macrophage activation involved in immune response);GO:0030282(bone mineralization);GO:0030316(osteoclast differentiation);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0061430(bone trabecula morphogenesis);GO:0071348(cellular response to interleukin-11);GO:0072674(multinuclear osteoclast differentiation);GO:0072675(osteoclast fusion);GO:1990830(cellular response to leukemia inhibitory factor);GO:1990830(cellular response to leukemia inhibitory factor)","NA","NA","NA","strawberry notch homolog 2 [Source:HGNC Symbol;Acc:HGNC:29158]",{"v":28.5739971614851,"d":"28.57"},{"v":11.0675909456686,"d":"11.07"},{"v":2.581772067811,"d":"2.58"},{"v":1.36836163768848,"d":"1.37"},{"v":0.0968044612537177,"d":"0.10"},{"v":0.640093278656057,"d":"0.64"},"up","no"]
["MSTRG.9808","B4GALT5","ENST00000371711","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0046872(metal ion binding);GO:0016740(transferase activity);GO:0016757(transferase activity, transferring glycosyl groups);GO:0005794(Golgi apparatus);GO:0005975(carbohydrate metabolic process);GO:0006486(protein glycosylation);GO:0032580(Golgi cisterna membrane);GO:0070062(extracellular exosome);GO:0000139(Golgi membrane);GO:0003831(beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity);GO:0008378(galactosyltransferase activity);GO:0016266(O-glycan processing);GO:0018146(keratan sulfate biosynthetic process)","00512(Mucin type O-glycan biosynthesis)","K09905","EC:2.4.1.-","beta-1,4-galactosyltransferase 5 [Source:HGNC Symbol;Acc:HGNC:928]",{"v":26.135172,"d":"26.14"},{"v":10.129673,"d":"10.13"},{"v":2.58006077787506,"d":"2.58"},{"v":1.36740505127107,"d":"1.37"},{"v":0.0970296377605322,"d":"0.10"},{"v":0.640093278656057,"d":"0.64"},"up","no"]
["MSTRG.73","SLC35E2B","ENST00000611123;ENST00000480991;ENST00000617444;ENST00000614300;ENST00000481276","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016021(integral component of membrane)","NA","NA","NA","solute carrier family 35 member E2B [Source:HGNC Symbol;Acc:HGNC:33941]",{"v":10.2368444757594,"d":"10.24"},{"v":3.96560176962478,"d":"3.97"},{"v":2.58141010380071,"d":"2.58"},{"v":1.36815935790593,"d":"1.37"},{"v":0.0970602464902411,"d":"0.10"},{"v":0.640093278656057,"d":"0.64"},"up","no"]
["ENSG00000214110","LDHAP4","ENST00000397561","NA","NA","NA","NA","lactate dehydrogenase A pseudogene 4 [Source:HGNC Symbol;Acc:HGNC:6539]",{"v":0.801919,"d":"0.80"},{"v":1.513098,"d":"1.51"},{"v":0.529984839052064,"d":"0.53"},{"v":-0.915977004904446,"d":"-0.92"},{"v":0.0970789993524772,"d":"0.10"},{"v":0.640093278656057,"d":"0.64"},"down","no"]
["MSTRG.9057","CHCHD5","ENST00000324913;ENST00000409719;ENST00000489052;MSTRG.9057.2;ENST00000469030;ENST00000454841","GO:0005739(mitochondrion);GO:0009060(aerobic respiration);GO:0005758(mitochondrial intermembrane space);GO:0005758(mitochondrial intermembrane space)","NA","NA","NA","coiled-coil-helix-coiled-coil-helix domain containing 5 [Source:HGNC Symbol;Acc:HGNC:17840]",{"v":1.0123258334498,"d":"1.01"},{"v":1.82140703843466,"d":"1.82"},{"v":0.555793302698449,"d":"0.56"},{"v":-0.847379644699283,"d":"-0.85"},{"v":0.0970895508778999,"d":"0.10"},{"v":0.640093278656057,"d":"0.64"},"down","no"]
["MSTRG.14317","NSD3","ENST00000317025;ENST00000527502;ENST00000433384;ENST00000316985;ENST00000528627;ENST00000528304;ENST00000525081;ENST00000526050;ENST00000528828;ENST00000529223;ENST00000534539","GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0008168(methyltransferase activity);GO:0016740(transferase activity);GO:0032259(methylation);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0016569(covalent chromatin modification);GO:0005694(chromosome);GO:0005515(protein binding);GO:0018024(histone-lysine N-methyltransferase activity);GO:0034968(histone lysine methylation);GO:0005654(nucleoplasm);GO:0016571(histone methylation);GO:0016571(histone methylation)","00310(Lysine degradation);00310(Lysine degradation)","K11425","EC:2.1.1.43","nuclear receptor binding SET domain protein 3 [Source:HGNC Symbol;Acc:HGNC:12767]",{"v":5.96749186827957,"d":"5.97"},{"v":2.31177094007343,"d":"2.31"},{"v":2.58135084442666,"d":"2.58"},{"v":1.36812623872573,"d":"1.37"},{"v":0.097132671661608,"d":"0.10"},{"v":0.640093278656057,"d":"0.64"},"up","no"]
["ENSG00000165650","PDZD8","ENST00000334464;ENST00000489302","GO:0005622(intracellular);GO:0016020(membrane);GO:0046872(metal ion binding);GO:0035556(intracellular signal transduction);GO:0007010(cytoskeleton organization);GO:0022604(regulation of cell morphogenesis);GO:0016032(viral process);GO:0016032(viral process)","NA","NA","NA","PDZ domain containing 8 [Source:HGNC Symbol;Acc:HGNC:26974]",{"v":3.57427053213237,"d":"3.57"},{"v":1.38384440724623,"d":"1.38"},{"v":2.58285578452057,"d":"2.58"},{"v":1.36896709186264,"d":"1.37"},{"v":0.09714968730236,"d":"0.10"},{"v":0.640093278656057,"d":"0.64"},"up","no"]
["MSTRG.8407","MBOAT7","ENST00000245615;ENST00000494142;ENST00000391754;MSTRG.8407.1;ENST00000491216;ENST00000453320;ENST00000495968;ENST00000437868;ENST00000474910;ENST00000464098;ENST00000338624;ENST00000449249;ENST00000414665;ENST00000431666;ENST00000495279","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016740(transferase activity);GO:0016746(transferase activity, transferring acyl groups);GO:0006629(lipid metabolic process);GO:0005515(protein binding);GO:0008654(phospholipid biosynthetic process);GO:0005789(endoplasmic reticulum membrane);GO:0003841(1-acylglycerol-3-phosphate O-acyltransferase activity);GO:0006644(phospholipid metabolic process);GO:0036149(phosphatidylinositol acyl-chain remodeling);GO:0021819(layer formation in cerebral cortex);GO:0047144(2-acylglycerol-3-phosphate O-acyltransferase activity);GO:0071617(lysophospholipid acyltransferase activity);GO:0021591(ventricular system development);GO:0046488(phosphatidylinositol metabolic process);GO:0046488(phosphatidylinositol metabolic process)","00564(Glycerophospholipid metabolism);00564(Glycerophospholipid metabolism)","K13516","EC:2.3.1.-","membrane bound O-acyltransferase domain containing 7 [Source:HGNC Symbol;Acc:HGNC:15505]",{"v":43.3839299703554,"d":"43.38"},{"v":16.8211389316885,"d":"16.82"},{"v":2.57913154076782,"d":"2.58"},{"v":1.36688535528065,"d":"1.37"},{"v":0.097174240099081,"d":"0.10"},{"v":0.640093278656057,"d":"0.64"},"up","no"]
["MSTRG.8978","ANKRD23","MSTRG.8978.1","NA","NA","NA","NA",null,{"v":8.037643,"d":"8.04"},{"v":2.971954,"d":"2.97"},{"v":2.7044977815942,"d":"2.70"},{"v":1.43536071409915,"d":"1.44"},{"v":0.0973568032552534,"d":"0.10"},{"v":0.640457321598517,"d":"0.64"},"up","no"]
["MSTRG.8715","RPS27A","ENST00000272317;ENST00000495843;ENST00000478196;ENST00000404735;ENST00000471772;ENST00000468810;ENST00000449323;ENST00000463185;ENST00000402285;ENST00000639844;ENST00000494756","GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0006412(translation);GO:0046872(metal ion binding);GO:0030529(intracellular ribonucleoprotein complex);GO:0003735(structural constituent of ribosome);GO:0005840(ribosome);GO:0005515(protein binding);GO:0044322(endoplasmic reticulum quality control compartment);GO:0022627(cytosolic small ribosomal subunit);GO:0005615(extracellular space);GO:0005730(nucleolus);GO:0038095(Fc-epsilon receptor signaling pathway);GO:0005886(plasma membrane);GO:0016567(protein ubiquitination);GO:0005789(endoplasmic reticulum membrane);GO:0006977(DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0034220(ion transmembrane transport);GO:0044267(cellular protein metabolic process);GO:0061024(membrane organization);GO:0016197(endosomal transport);GO:0019058(viral life cycle);GO:0075733(intracellular transport of virus);GO:0010008(endosome membrane);GO:0043657(host cell);GO:0000165(MAPK cascade);GO:0000209(protein polyubiquitination);GO:0002223(stimulatory C-type lectin receptor signaling pathway);GO:0010972(negative regulation of G2/M transition of mitotic cell cycle);GO:0016579(protein deubiquitination);GO:0031145(anaphase-promoting complex-dependent catabolic process);GO:0031146(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process);GO:0033209(tumor necrosis factor-mediated signaling pathway);GO:0038061(NIK/NF-kappaB signaling);GO:0043161(proteasome-mediated ubiquitin-dependent protein catabolic process);GO:0043488(regulation of mRNA stability);GO:0050852(T cell receptor signaling pathway);GO:0051437(positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition);GO:0055085(transmembrane transport);GO:0060071(Wnt signaling pathway, planar cell polarity pathway);GO:0061418(regulation of transcription from RNA polymerase II promoter in response to hypoxia);GO:0090090(negative regulation of canonical Wnt signaling pathway);GO:0090263(positive regulation of canonical Wnt signaling pathway);GO:1902036(regulation of hematopoietic stem cell differentiation);GO:0045087(innate immune response);GO:0000086(G2/M transition of mitotic cell cycle);GO:0036297(interstrand cross-link repair);GO:0006457(protein folding);GO:0002755(MyD88-dependent toll-like receptor signaling pathway);GO:0002756(MyD88-independent toll-like receptor signaling pathway);GO:0007249(I-kappaB kinase/NF-kappaB signaling);GO:0035666(TRIF-dependent toll-like receptor signaling pathway);GO:0051436(negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle);GO:1904380(endoplasmic reticulum mannose trimming);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:1901796(regulation of signal transduction by p53 class mediator);GO:0031982(vesicle);GO:0006413(translational initiation);GO:0030666(endocytic vesicle membrane);GO:0005741(mitochondrial outer membrane);GO:0006364(rRNA processing);GO:0007219(Notch signaling pathway);GO:0016055(Wnt signaling pathway);GO:0042787(protein ubiquitination involved in ubiquitin-dependent protein catabolic process);GO:0038128(ERBB2 signaling pathway);GO:0007254(JNK cascade);GO:0043065(positive regulation of apoptotic process);GO:0010803(regulation of tumor necrosis factor-mediated signaling pathway);GO:0043066(negative regulation of apoptotic process);GO:0043123(positive regulation of I-kappaB kinase/NF-kappaB signaling);GO:0051092(positive regulation of NF-kappaB transcription factor activity);GO:0051403(stress-activated MAPK cascade);GO:0070423(nucleotide-binding oligomerization domain containing signaling pathway);GO:0019985(translesion synthesis);GO:0032480(negative regulation of type I interferon production);GO:0042059(negative regulation of epidermal growth factor receptor signaling pathway);GO:0030512(negative regulation of transforming growth factor beta receptor signaling pathway);GO:0000184(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay);GO:0005978(glycogen biosynthetic process);GO:0019083(viral transcription);GO:0006283(transcription-coupled nucleotide-excision repair);GO:0008543(fibroblast growth factor receptor signaling pathway);GO:0000187(activation of MAPK activity);GO:0016236(macroautophagy);GO:0042276(error-prone translesion synthesis);GO:0035635(entry of bacterium into host cell);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0006614(SRP-dependent cotranslational protein targeting to membrane);GO:0042769(DNA damage response, detection of DNA damage);GO:0007179(transforming growth factor beta receptor signaling pathway);GO:0006879(cellular iron ion homeostasis);GO:0006296(nucleotide-excision repair, DNA incision, 5'-to lesion);GO:0033683(nucleotide-excision repair, DNA incision);GO:0070911(global genome nucleotide-excision repair);GO:0000715(nucleotide-excision repair, DNA damage recognition);GO:0000717(nucleotide-excision repair, DNA duplex unwinding);GO:0006294(nucleotide-excision repair, preincision complex assembly);GO:0006297(nucleotide-excision repair, DNA gap filling);GO:0019068(virion assembly);GO:0032479(regulation of type I interferon production);GO:0045742(positive regulation of epidermal growth factor receptor signaling pathway);GO:0060544(regulation of necroptotic process);GO:0070987(error-free translesion synthesis);GO:0015935(small ribosomal subunit);GO:0043209(myelin sheath);GO:0043209(myelin sheath)","03010(Ribosome);03010(Ribosome)","K02977","NA","ribosomal protein S27a [Source:HGNC Symbol;Acc:HGNC:10417]",{"v":74.5736597702875,"d":"74.57"},{"v":132.270782808946,"d":"132.27"},{"v":0.563795406563843,"d":"0.56"},{"v":-0.826756371066576,"d":"-0.83"},{"v":0.0973722275807182,"d":"0.10"},{"v":0.640457321598517,"d":"0.64"},"down","no"]
["ENSG00000166263","STXBP4","ENST00000376352;ENST00000461444;ENST00000405898;ENST00000464340","GO:0005737(cytoplasm);GO:0006974(cellular response to DNA damage stimulus);GO:0005515(protein binding);GO:0070062(extracellular exosome);GO:0050821(protein stabilization);GO:0019905(syntaxin binding);GO:0010838(positive regulation of keratinocyte proliferation);GO:0061178(regulation of insulin secretion involved in cellular response to glucose stimulus);GO:1902808(positive regulation of cell cycle G1/S phase transition);GO:0006605(protein targeting);GO:0008286(insulin receptor signaling pathway);GO:0015758(glucose transport);GO:0015758(glucose transport)","NA","NA","NA","syntaxin binding protein 4 [Source:HGNC Symbol;Acc:HGNC:19694]",{"v":0.260704865134312,"d":"0.26"},{"v":0.0973086505123235,"d":"0.10"},{"v":2.67915405014578,"d":"2.68"},{"v":1.42177753787745,"d":"1.42"},{"v":0.0973949565093413,"d":"0.10"},{"v":0.640457321598517,"d":"0.64"},"up","no"]
["MSTRG.6583","PHF12","ENST00000332830;ENST00000577226;ENST00000268756;ENST00000483934;ENST00000584685;ENST00000582853;ENST00000578900;ENST00000582655;ENST00000582436;ENST00000584822;ENST00000378879;ENST00000579036;ENST00000579563;ENST00000584236;ENST00000583747","GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0005654(nucleoplasm);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003682(chromatin binding);GO:0035091(phosphatidylinositol binding);GO:0005515(protein binding);GO:0000977(RNA polymerase II regulatory region sequence-specific DNA binding);GO:0045892(negative regulation of transcription, DNA-templated);GO:0042393(histone binding);GO:0017053(transcriptional repressor complex);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0001106(RNA polymerase II transcription corepressor activity);GO:0001222(transcription corepressor binding);GO:0016580(Sin3 complex);GO:0016580(Sin3 complex)","NA","NA","NA","PHD finger protein 12 [Source:HGNC Symbol;Acc:HGNC:20816]",{"v":7.31648106690112,"d":"7.32"},{"v":2.8377193291895,"d":"2.84"},{"v":2.57829623657348,"d":"2.58"},{"v":1.36641803347553,"d":"1.37"},{"v":0.0978199307362348,"d":"0.10"},{"v":0.642212796862318,"d":"0.64"},"up","no"]
["MSTRG.5276","ARID3B","ENST00000346246;ENST00000563567;ENST00000566468;ENST00000569680;ENST00000622429;MSTRG.5276.3","GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0006366(transcription from RNA polymerase II promoter);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0008150(biological_process);GO:0000977(RNA polymerase II regulatory region sequence-specific DNA binding);GO:0001228(transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:0000980(RNA polymerase II distal enhancer sequence-specific DNA binding);GO:0001077(transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0001205(transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0045944(positive regulation of transcription from RNA polymerase II promoter)","NA","NA","NA","AT-rich interaction domain 3B [Source:HGNC Symbol;Acc:HGNC:14350]",{"v":5.87374810206053,"d":"5.87"},{"v":2.27706831084997,"d":"2.28"},{"v":2.57952213118631,"d":"2.58"},{"v":1.36710382424433,"d":"1.37"},{"v":0.0978989090032743,"d":"0.10"},{"v":0.642212796862318,"d":"0.64"},"up","no"]
["ENSG00000147124","ZNF41","ENST00000465311;ENST00000377065;ENST00000432977;ENST00000313116","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0005622(intracellular);GO:0005515(protein binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding)","NA","NA","NA","zinc finger protein 41 [Source:HGNC Symbol;Acc:HGNC:13107]",{"v":0.347343450459866,"d":"0.35"},{"v":0.632796551003345,"d":"0.63"},{"v":0.548902249718535,"d":"0.55"},{"v":-0.865378842565012,"d":"-0.87"},{"v":0.0979336057586105,"d":"0.10"},{"v":0.642212796862318,"d":"0.64"},"down","no"]
["ENSG00000096092","TMEM14A","ENST00000211314","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005515(protein binding)","NA","NA","NA","transmembrane protein 14A [Source:HGNC Symbol;Acc:HGNC:21076]",{"v":1.155096,"d":"1.16"},{"v":2.134101,"d":"2.13"},{"v":0.54125648223772,"d":"0.54"},{"v":-0.885615696828671,"d":"-0.89"},{"v":0.0979339949808721,"d":"0.10"},{"v":0.642212796862318,"d":"0.64"},"down","no"]
["MSTRG.5581","IL32","ENST00000552664;ENST00000552356;ENST00000529550;ENST00000548807;ENST00000525377;ENST00000526464;ENST00000548476;ENST00000008180;ENST00000528652;ENST00000528163;ENST00000396890;ENST00000525643;ENST00000444393;ENST00000530538;ENST00000533097;ENST00000440815;ENST00000525228;ENST00000548652;ENST00000549213;ENST00000529699;ENST00000325568;ENST00000525003;ENST00000551513;ENST00000613483;ENST00000396887;ENST00000532247;ENST00000531965;ENST00000532086;ENST00000534507;ENST00000534748;ENST00000551122;ENST00000382213;ENST00000530890","GO:0016020(membrane);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0006955(immune response);GO:0005125(cytokine activity);GO:0005615(extracellular space);GO:0005829(cytosol);GO:0007155(cell adhesion);GO:0006952(defense response);GO:0006952(defense response)","NA","NA","NA","interleukin 32 [Source:HGNC Symbol;Acc:HGNC:16830]",{"v":38.540382100966,"d":"38.54"},{"v":68.2949323225304,"d":"68.29"},{"v":0.564322721910826,"d":"0.56"},{"v":-0.825407655409447,"d":"-0.83"},{"v":0.0979428248140639,"d":"0.10"},{"v":0.642212796862318,"d":"0.64"},"down","no"]
["ENSG00000145029","NICN1","ENST00000273598;ENST00000494057;ENST00000436744;ENST00000497742","GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005874(microtubule);GO:0005874(microtubule)","NA","NA","NA","nicolin 1 [Source:HGNC Symbol;Acc:HGNC:18317]",{"v":0.458762608740184,"d":"0.46"},{"v":0.83856770331171,"d":"0.84"},{"v":0.547078795103147,"d":"0.55"},{"v":-0.870179457266676,"d":"-0.87"},{"v":0.0979937204891095,"d":"0.10"},{"v":0.642212796862318,"d":"0.64"},"down","no"]
["MSTRG.14794","LINC01506","ENST00000446290;ENST00000432148","NA","NA","NA","NA","long intergenic non-protein coding RNA 1506 [Source:HGNC Symbol;Acc:HGNC:51187]",{"v":5.63505484980989,"d":"5.64"},{"v":10.1211335361217,"d":"10.12"},{"v":0.556761239212854,"d":"0.56"},{"v":-0.844869318222776,"d":"-0.84"},{"v":0.0981685008793881,"d":"0.10"},{"v":0.64299537547227,"d":"0.64"},"down","no"]
["ENSG00000077235","GTF3C1","ENST00000561623;ENST00000356183;ENST00000564747;ENST00000562609;ENST00000564664;ENST00000567843;ENST00000569653;ENST00000568569;ENST00000570129;ENST00000566779;ENST00000571886","GO:0005634(nucleus);GO:0016020(membrane);GO:0005730(nucleolus);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0006359(regulation of transcription from RNA polymerase III promoter);GO:0005654(nucleoplasm);GO:0009303(rRNA transcription);GO:0006384(transcription initiation from RNA polymerase III promoter);GO:0000995(transcription factor activity, core RNA polymerase III binding);GO:0001002(RNA polymerase III type 1 promoter sequence-specific DNA binding);GO:0001003(RNA polymerase III type 2 promoter sequence-specific DNA binding);GO:0001007(transcription factor activity, RNA polymerase III transcription factor binding);GO:0006383(transcription from RNA polymerase III promoter);GO:0009304(tRNA transcription);GO:0042791(5S class rRNA transcription from RNA polymerase III type 1 promoter);GO:0042797(tRNA transcription from RNA polymerase III promoter);GO:0000127(transcription factor TFIIIC complex);GO:0030529(intracellular ribonucleoprotein complex);GO:0030529(intracellular ribonucleoprotein complex)","NA","NA","NA","general transcription factor IIIC subunit 1 [Source:HGNC Symbol;Acc:HGNC:4664]",{"v":4.35659859513925,"d":"4.36"},{"v":1.69005563077322,"d":"1.69"},{"v":2.57778413669499,"d":"2.58"},{"v":1.36613145766441,"d":"1.37"},{"v":0.0984401995272821,"d":"0.10"},{"v":0.644411520355314,"d":"0.64"},"up","no"]
["MSTRG.12977","RPL10A","ENST00000478340;ENST00000464112;ENST00000322203;ENST00000467020;ENST00000490335","GO:0003723(RNA binding);GO:0005634(nucleus);GO:0016020(membrane);GO:0006412(translation);GO:0030529(intracellular ribonucleoprotein complex);GO:0003735(structural constituent of ribosome);GO:0005840(ribosome);GO:0005515(protein binding);GO:0015934(large ribosomal subunit);GO:0005925(focal adhesion);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0006413(translational initiation);GO:0006364(rRNA processing);GO:0000184(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay);GO:0019083(viral transcription);GO:0000470(maturation of LSU-rRNA);GO:0006614(SRP-dependent cotranslational protein targeting to membrane);GO:0022625(cytosolic large ribosomal subunit);GO:0045471(response to ethanol);GO:0045471(response to ethanol)","03010(Ribosome);03010(Ribosome)","K02865","NA","ribosomal protein L10a [Source:HGNC Symbol;Acc:HGNC:10299]",{"v":228.635577260493,"d":"228.64"},{"v":404.378459291139,"d":"404.38"},{"v":0.565399991041271,"d":"0.57"},{"v":-0.82265623457769,"d":"-0.82"},{"v":0.0985259020639042,"d":"0.10"},{"v":0.644427384789701,"d":"0.64"},"down","no"]
["MSTRG.1814","VCL","ENST00000372755;ENST00000211998;ENST00000624354;ENST00000623461;ENST00000472585","GO:0003779(actin binding);GO:0051015(actin filament binding);GO:0007155(cell adhesion);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005198(structural molecule activity);GO:0005925(focal adhesion);GO:0015629(actin cytoskeleton);GO:0005886(plasma membrane);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0030054(cell junction);GO:0005576(extracellular region);GO:0005829(cytosol);GO:0045296(cadherin binding);GO:0070062(extracellular exosome);GO:0043234(protein complex);GO:0005912(adherens junction);GO:0043312(neutrophil degranulation);GO:0005913(cell-cell adherens junction);GO:0070527(platelet aggregation);GO:0002576(platelet degranulation);GO:0030032(lamellipodium assembly);GO:0034774(secretory granule lumen);GO:1904813(ficolin-1-rich granule lumen);GO:0035580(specific granule lumen);GO:0002162(dystroglycan binding);GO:0005911(cell-cell junction);GO:1903561(extracellular vesicle);GO:0045294(alpha-catenin binding);GO:0006936(muscle contraction);GO:0008013(beta-catenin binding);GO:0043034(costamere);GO:0006928(movement of cell or subcellular component);GO:0034333(adherens junction assembly);GO:0030336(negative regulation of cell migration);GO:0031625(ubiquitin protein ligase binding);GO:0043297(apical junction assembly);GO:0007160(cell-matrix adhesion);GO:0002009(morphogenesis of an epithelium);GO:0030334(regulation of cell migration);GO:0034394(protein localization to cell surface);GO:0048675(axon extension);GO:0090136(epithelial cell-cell adhesion);GO:0002102(podosome);GO:0005916(fascia adherens);GO:0030055(cell-substrate junction);GO:0005623(cell);GO:0005903(brush border);GO:0005915(zonula adherens);GO:0090636(outer dense plaque of desmosome);GO:0090637(inner dense plaque of desmosome);GO:1990357(terminal web);GO:1990357(terminal web)","04510(Focal adhesion);04520(Adherens junction);04810(Regulation of actin cytoskeleton);04670(Leukocyte transendothelial migration);05131(Shigellosis);05100(Bacterial invasion of epithelial cells);05146(Amoebiasis);05146(Amoebiasis)","K05700","NA","vinculin [Source:HGNC Symbol;Acc:HGNC:12665]",{"v":22.1521322803243,"d":"22.15"},{"v":8.6183633433747,"d":"8.62"},{"v":2.57034095659863,"d":"2.57"},{"v":1.36195974609909,"d":"1.36"},{"v":0.0985536067671151,"d":"0.10"},{"v":0.644427384789701,"d":"0.64"},"up","no"]
["MSTRG.9203","AC009487.2","ENST00000420969","NA","NA","NA","NA",null,{"v":1.571964,"d":"1.57"},{"v":0.605851,"d":"0.61"},{"v":2.59463795553692,"d":"2.59"},{"v":1.37553324525334,"d":"1.38"},{"v":0.09876632277588,"d":"0.10"},{"v":0.645188983994628,"d":"0.65"},"up","no"]
["MSTRG.12524","MAT2B","ENST00000523606;ENST00000280969;MSTRG.12524.5;ENST00000518095;ENST00000321757;ENST00000421814;ENST00000521838;ENST00000520449","GO:0005634(nucleus);GO:0006730(one-carbon metabolic process);GO:0050790(regulation of catalytic activity);GO:0005515(protein binding);GO:0006556(S-adenosylmethionine biosynthetic process);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0005622(intracellular);GO:0019899(enzyme binding);GO:0032259(methylation);GO:0048269(methionine adenosyltransferase complex);GO:0048270(methionine adenosyltransferase regulator activity);GO:0005739(mitochondrion);GO:0005739(mitochondrion)","00270(Cysteine and methionine metabolism);00270(Cysteine and methionine metabolism)","K00789","EC:2.5.1.6","methionine adenosyltransferase 2B [Source:HGNC Symbol;Acc:HGNC:6905]",{"v":11.484311980982,"d":"11.48"},{"v":20.3191350560838,"d":"20.32"},{"v":0.565196891958423,"d":"0.57"},{"v":-0.823174562634652,"d":"-0.82"},{"v":0.0987920161936789,"d":"0.10"},{"v":0.645188983994628,"d":"0.65"},"down","no"]
["ENSG00000186827","TNFRSF4","ENST00000379236;ENST00000497869","GO:0043433(negative regulation of sequence-specific DNA binding transcription factor activity);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005886(plasma membrane);GO:0006954(inflammatory response);GO:0046718(viral entry into host cell);GO:0097190(apoptotic signaling pathway);GO:0033209(tumor necrosis factor-mediated signaling pathway);GO:0016032(viral process);GO:0005887(integral component of plasma membrane);GO:0009986(cell surface);GO:0006955(immune response);GO:0007275(multicellular organism development);GO:0032496(response to lipopolysaccharide);GO:0042127(regulation of cell proliferation);GO:0042981(regulation of apoptotic process);GO:0045892(negative regulation of transcription, DNA-templated);GO:0001618(virus receptor activity);GO:0051024(positive regulation of immunoglobulin secretion);GO:0030890(positive regulation of B cell proliferation);GO:0005031(tumor necrosis factor-activated receptor activity);GO:0042098(T cell proliferation);GO:0042098(T cell proliferation)","04060(Cytokine-cytokine receptor interaction);04060(Cytokine-cytokine receptor interaction)","K05142","NA","TNF receptor superfamily member 4 [Source:HGNC Symbol;Acc:HGNC:11918]",{"v":0.685994210342824,"d":"0.69"},{"v":1.26037547065659,"d":"1.26"},{"v":0.544277658772157,"d":"0.54"},{"v":-0.877585276608887,"d":"-0.88"},{"v":0.0988603767384304,"d":"0.10"},{"v":0.645188983994628,"d":"0.65"},"down","no"]
["ENSG00000277117","FP565260.3","ENST00000623960;ENST00000623795","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016021(integral component of membrane)","04514(Cell adhesion molecules (CAMs));04672(Intestinal immune network for IgA production);04672(Intestinal immune network for IgA production)","K06710","NA",null,{"v":0.325195877271373,"d":"0.33"},{"v":0.594100046470063,"d":"0.59"},{"v":0.547375613254997,"d":"0.55"},{"v":-0.869396933877949,"d":"-0.87"},{"v":0.0990671929698829,"d":"0.10"},{"v":0.645188983994628,"d":"0.65"},"down","no"]
["MSTRG.11976","OTULIN","ENST00000284274;ENST00000508678;ENST00000506417;ENST00000503023;ENST00000514913;ENST00000507335","GO:0004843(thiol-dependent ubiquitin-specific protease activity);GO:1990108(protein linear deubiquitination);GO:0005737(cytoplasm);GO:0016787(hydrolase activity);GO:0005515(protein binding);GO:0008233(peptidase activity);GO:0008234(cysteine-type peptidase activity);GO:0006508(proteolysis);GO:0036459(thiol-dependent ubiquitinyl hydrolase activity);GO:0016055(Wnt signaling pathway);GO:0002376(immune system process);GO:0045087(innate immune response);GO:0016567(protein ubiquitination);GO:0002040(sprouting angiogenesis);GO:0005829(cytosol);GO:0070431(nucleotide-binding oligomerization domain containing 2 signaling pathway);GO:0032088(negative regulation of NF-kappaB transcription factor activity);GO:0050728(negative regulation of inflammatory response);GO:0001525(angiogenesis);GO:0010803(regulation of tumor necrosis factor-mediated signaling pathway);GO:0060070(canonical Wnt signaling pathway);GO:0071797(LUBAC complex);GO:0071797(LUBAC complex)","NA","NA","NA","OTU deubiquitinase with linear linkage specificity [Source:HGNC Symbol;Acc:HGNC:25118]",{"v":1.30662681901556,"d":"1.31"},{"v":0.505057423960994,"d":"0.51"},{"v":2.58708566001887,"d":"2.59"},{"v":1.37132782334561,"d":"1.37"},{"v":0.0990945000142607,"d":"0.10"},{"v":0.645188983994628,"d":"0.65"},"up","no"]
["MSTRG.8752","AC012368.1","MSTRG.8752.5;ENST00000451350;ENST00000436950;ENST00000426365;ENST00000449678;ENST00000413030;ENST00000438115","NA","NA","NA","NA",null,{"v":4.62477893591654,"d":"4.62"},{"v":8.20929718591654,"d":"8.21"},{"v":0.563358693342297,"d":"0.56"},{"v":-0.827874308765767,"d":"-0.83"},{"v":0.0991079030412931,"d":"0.10"},{"v":0.645188983994628,"d":"0.65"},"down","no"]
["ENSG00000267080","ASB16-AS1","ENST00000585457;ENST00000592897;ENST00000591166","NA","NA","NA","NA","ASB16 antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:25442]",{"v":1.46018726097561,"d":"1.46"},{"v":0.548735313821138,"d":"0.55"},{"v":2.66100472157978,"d":"2.66"},{"v":1.41197107022247,"d":"1.41"},{"v":0.0991612491373449,"d":"0.10"},{"v":0.645188983994628,"d":"0.65"},"up","no"]
["ENSG00000104221","BRF2","ENST00000220659;ENST00000522539;ENST00000520601","GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0070897(DNA-templated transcriptional preinitiation complex assembly);GO:0005654(nucleoplasm);GO:0034599(cellular response to oxidative stress);GO:0006359(regulation of transcription from RNA polymerase III promoter);GO:0001032(RNA polymerase III type 3 promoter DNA binding);GO:0001007(transcription factor activity, RNA polymerase III transcription factor binding);GO:0001007(transcription factor activity, RNA polymerase III transcription factor binding)","NA","NA","NA","BRF2, RNA polymerase III transcription initiation factor subunit [Source:HGNC Symbol;Acc:HGNC:17298]",{"v":1.27441331195652,"d":"1.27"},{"v":2.28207133731884,"d":"2.28"},{"v":0.558445869380141,"d":"0.56"},{"v":-0.840510649024906,"d":"-0.84"},{"v":0.099237346104458,"d":"0.10"},{"v":0.645188983994628,"d":"0.65"},"down","no"]
["ENSG00000215421","ZNF407","ENST00000299687;ENST00000582337;ENST00000579200","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0003677(DNA binding)","NA","NA","NA","zinc finger protein 407 [Source:HGNC Symbol;Acc:HGNC:19904]",{"v":1.35956383822806,"d":"1.36"},{"v":0.526192233962264,"d":"0.53"},{"v":2.58377784862093,"d":"2.58"},{"v":1.36948203347203,"d":"1.37"},{"v":0.0992817088013371,"d":"0.10"},{"v":0.645188983994628,"d":"0.65"},"up","no"]
["ENSG00000178904","DPY19L3","ENST00000342179;ENST00000592142;ENST00000592503;ENST00000392250;ENST00000588648;ENST00000608291;ENST00000590651;ENST00000592832;ENST00000586987;ENST00000587077;ENST00000585597;ENST00000586427","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016740(transferase activity);GO:0016757(transferase activity, transferring glycosyl groups);GO:0000030(mannosyltransferase activity);GO:0005637(nuclear inner membrane);GO:0018406(protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan);GO:0018406(protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan)","NA","NA","NA","dpy-19 like 3 (C. elegans) [Source:HGNC Symbol;Acc:HGNC:27120]",{"v":1.162052425749,"d":"1.16"},{"v":0.447626352471941,"d":"0.45"},{"v":2.5960322025988,"d":"2.60"},{"v":1.37630827942389,"d":"1.38"},{"v":0.0992911886683924,"d":"0.10"},{"v":0.645188983994628,"d":"0.65"},"up","no"]
["ENSG00000101911","PRPS2","ENST00000380668;ENST00000398491;ENST00000489404","GO:0000287(magnesium ion binding);GO:0004749(ribose phosphate diphosphokinase activity);GO:0009165(nucleotide biosynthetic process);GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0016740(transferase activity);GO:0009116(nucleoside metabolic process);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0042803(protein homodimerization activity);GO:0005515(protein binding);GO:0042802(identical protein binding);GO:0009156(ribonucleoside monophosphate biosynthetic process);GO:0044249(cellular biosynthetic process);GO:0070062(extracellular exosome);GO:0006139(nucleobase-containing compound metabolic process);GO:0006015(5-phosphoribose 1-diphosphate biosynthetic process);GO:0016208(AMP binding);GO:0019003(GDP binding);GO:0030246(carbohydrate binding);GO:0043531(ADP binding);GO:0006167(AMP biosynthetic process);GO:0019693(ribose phosphate metabolic process);GO:0031100(animal organ regeneration);GO:0002189(ribose phosphate diphosphokinase complex);GO:0043234(protein complex);GO:0043234(protein complex)","00030(Pentose phosphate pathway);00230(Purine metabolism);00230(Purine metabolism)","K00948","EC:2.7.6.1","phosphoribosyl pyrophosphate synthetase 2 [Source:HGNC Symbol;Acc:HGNC:9465]",{"v":2.20717911493836,"d":"2.21"},{"v":3.93097304205946,"d":"3.93"},{"v":0.561484164689668,"d":"0.56"},{"v":-0.832682759431272,"d":"-0.83"},{"v":0.09931114432979,"d":"0.10"},{"v":0.645188983994628,"d":"0.65"},"down","no"]
["ENSG00000166896","ATP23","ENST00000300145;ENST00000551997","GO:0043231(intracellular membrane-bounded organelle);GO:0046872(metal ion binding);GO:0016787(hydrolase activity);GO:0006468(protein phosphorylation);GO:0005886(plasma membrane);GO:0008233(peptidase activity);GO:0006508(proteolysis);GO:0004222(metalloendopeptidase activity);GO:0008237(metallopeptidase activity);GO:0006303(double-strand break repair via nonhomologous end joining);GO:0005958(DNA-dependent protein kinase-DNA ligase 4 complex);GO:0004677(DNA-dependent protein kinase activity);GO:0004677(DNA-dependent protein kinase activity)","NA","NA","NA","ATP23 metallopeptidase and ATP synthase assembly factor homolog [Source:HGNC Symbol;Acc:HGNC:29452]",{"v":1.11151576766205,"d":"1.11"},{"v":2.04705054042243,"d":"2.05"},{"v":0.542984037625508,"d":"0.54"},{"v":-0.881018307865113,"d":"-0.88"},{"v":0.0993367694292943,"d":"0.10"},{"v":0.645188983994628,"d":"0.65"},"down","no"]
["ENSG00000110628","SLC22A18","ENST00000312221;ENST00000347936;ENST00000441077;ENST00000495518;ENST00000498244;ENST00000463571;ENST00000498209;ENST00000380574;ENST00000467719;ENST00000485423","GO:0006810(transport);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005215(transporter activity);GO:0055085(transmembrane transport);GO:0015293(symporter activity);GO:0006811(ion transport);GO:0005886(plasma membrane);GO:0031625(ubiquitin protein ligase binding);GO:0016324(apical plasma membrane);GO:0015238(drug transmembrane transporter activity);GO:0006855(drug transmembrane transport);GO:0015893(drug transport);GO:0005635(nuclear envelope);GO:0015695(organic cation transport);GO:0007588(excretion);GO:0015307(drug:proton antiporter activity);GO:0046618(drug export);GO:0046618(drug export)","NA","NA","NA","solute carrier family 22 member 18 [Source:HGNC Symbol;Acc:HGNC:10964]",{"v":1.69599039973664,"d":"1.70"},{"v":0.64509654420617,"d":"0.65"},{"v":2.62904896169248,"d":"2.63"},{"v":1.39454101001727,"d":"1.39"},{"v":0.0994209317651499,"d":"0.10"},{"v":0.645374667741021,"d":"0.65"},"up","no"]
["MSTRG.5149","ANXA2","ENST00000451270;ENST00000421017;ENST00000557904;ENST00000396024;ENST00000559176;ENST00000557937;ENST00000560546;ENST00000558998;ENST00000332680;ENST00000557906;ENST00000558503;ENST00000560468;ENST00000559113;ENST00000561022;ENST00000561445;ENST00000558169;ENST00000560936;ENST00000558985;ENST00000559956;ENST00000560466;ENST00000560495;ENST00000558558;ENST00000560014;ENST00000559559;ENST00000557986;ENST00000560389;ENST00000559647;ENST00000559818;ENST00000504475;ENST00000559780;ENST00000559370;ENST00000560165;ENST00000559467;ENST00000560367","GO:0003723(RNA binding);GO:0005634(nucleus);GO:0016020(membrane);GO:0005509(calcium ion binding);GO:0005765(lysosomal membrane);GO:0005515(protein binding);GO:0008092(cytoskeletal protein binding);GO:0005576(extracellular region);GO:0043086(negative regulation of catalytic activity);GO:0042470(melanosome);GO:0005578(proteinaceous extracellular matrix);GO:0005615(extracellular space);GO:0004859(phospholipase inhibitor activity);GO:0005544(calcium-dependent phospholipid binding);GO:0045121(membrane raft);GO:0030496(midbody);GO:0005604(basement membrane);GO:0042802(identical protein binding);GO:0005768(endosome);GO:0031902(late endosome membrane);GO:0070062(extracellular exosome);GO:0031012(extracellular matrix);GO:0005546(phosphatidylinositol-4,5-bisphosphate binding);GO:0043312(neutrophil degranulation);GO:0005737(cytoplasm);GO:0098641(cadherin binding involved in cell-cell adhesion);GO:0098609(cell-cell adhesion);GO:0005913(cell-cell adherens junction);GO:0035722(interleukin-12-mediated signaling pathway);GO:0005886(plasma membrane);GO:0009986(cell surface);GO:0031982(vesicle);GO:0001525(angiogenesis);GO:0035578(azurophil granule lumen);GO:0005811(lipid particle);GO:0044548(S100 protein binding);GO:0051290(protein heterotetramerization);GO:0002020(protease binding);GO:0001765(membrane raft assembly);GO:0016323(basolateral plasma membrane);GO:0048306(calcium-dependent protein binding);GO:0030546(receptor activator activity);GO:0019834(phospholipase A2 inhibitor activity);GO:0031340(positive regulation of vesicle fusion);GO:0001921(positive regulation of receptor recycling);GO:0006900(membrane budding);GO:0032804(negative regulation of low-density lipoprotein particle receptor catabolic process);GO:0036035(osteoclast development);GO:0044090(positive regulation of vacuole organization);GO:0044147(negative regulation of development of symbiont involved in interaction with host);GO:0052362(catabolism by host of symbiont protein);GO:0052405(negative regulation by host of symbiont molecular function);GO:1905581(positive regulation of low-density lipoprotein particle clearance);GO:1905597(positive regulation of low-density lipoprotein particle receptor binding);GO:1905599(positive regulation of low-density lipoprotein receptor activity);GO:1905602(positive regulation of receptor-mediated endocytosis involved in cholesterol transport);GO:1990667(PCSK9-AnxA2 complex);GO:0017137(Rab GTPase binding);GO:0001934(positive regulation of protein phosphorylation);GO:0007589(body fluid secretion);GO:0030199(collagen fibril organization);GO:0042730(fibrinolysis);GO:0048146(positive regulation of fibroblast proliferation);GO:0051099(positive regulation of binding);GO:0072661(protein targeting to plasma membrane);GO:0097066(response to thyroid hormone);GO:0001726(ruffle);GO:0005769(early endosome);GO:0005829(cytosol);GO:0005938(cell cortex);GO:0019897(extrinsic component of plasma membrane);GO:0035749(myelin sheath adaxonal region);GO:0042383(sarcolemma);GO:0043220(Schmidt-Lanterman incisure);GO:0043234(protein complex);GO:0044354(macropinosome);GO:0048471(perinuclear region of cytoplasm);GO:0048471(perinuclear region of cytoplasm)","NA","NA","NA","annexin A2 [Source:HGNC Symbol;Acc:HGNC:537]",{"v":16.8999224339302,"d":"16.90"},{"v":29.8443827251813,"d":"29.84"},{"v":0.566268117841514,"d":"0.57"},{"v":-0.820442789725053,"d":"-0.82"},{"v":0.0995424981224412,"d":"0.10"},{"v":0.645802810444642,"d":"0.65"},"down","no"]
["MSTRG.14744","STOML2","ENST00000356493;ENST00000487490;ENST00000619795;ENST00000452248;ENST00000488050","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005743(mitochondrial inner membrane);GO:0005739(mitochondrion);GO:0005886(plasma membrane);GO:0005856(cytoskeleton);GO:0045121(membrane raft);GO:0008289(lipid binding);GO:0005515(protein binding);GO:0005758(mitochondrial intermembrane space);GO:0008180(COP9 signalosome);GO:0005102(receptor binding);GO:0051259(protein oligomerization);GO:0050852(T cell receptor signaling pathway);GO:0015629(actin cytoskeleton);GO:0007005(mitochondrion organization);GO:0001772(immunological synapse);GO:1901612(cardiolipin binding);GO:0051020(GTPase binding);GO:0006851(mitochondrial calcium ion transmembrane transport);GO:0006874(cellular calcium ion homeostasis);GO:0042776(mitochondrial ATP synthesis coupled proton transport);GO:0042101(T cell receptor complex);GO:0019897(extrinsic component of plasma membrane);GO:0010918(positive regulation of mitochondrial membrane potential);GO:0035710(CD4-positive, alpha-beta T cell activation);GO:0034982(mitochondrial protein processing);GO:0010876(lipid localization);GO:0032623(interleukin-2 production);GO:0090297(positive regulation of mitochondrial DNA replication);GO:1900210(positive regulation of cardiolipin metabolic process);GO:1990046(stress-induced mitochondrial fusion);GO:1990046(stress-induced mitochondrial fusion)","NA","NA","NA","stomatin like 2 [Source:HGNC Symbol;Acc:HGNC:14559]",{"v":9.0770102807309,"d":"9.08"},{"v":16.0666206788483,"d":"16.07"},{"v":0.564960763197751,"d":"0.56"},{"v":-0.82377741975894,"d":"-0.82"},{"v":0.0997316750990448,"d":"0.10"},{"v":0.645978970277976,"d":"0.65"},"down","no"]
["ENSG00000150457","LATS2","ENST00000382592;ENST00000472754","GO:0090090(negative regulation of canonical Wnt signaling pathway);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0005829(cytosol);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0051301(cell division);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0007049(cell cycle);GO:0005815(microtubule organizing center);GO:0000922(spindle pole);GO:0009755(hormone-mediated signaling pathway);GO:0018105(peptidyl-serine phosphorylation);GO:0045736(negative regulation of cyclin-dependent protein serine/threonine kinase activity);GO:0035556(intracellular signal transduction);GO:0035329(hippo signaling);GO:0043065(positive regulation of apoptotic process);GO:0046620(regulation of organ growth);GO:0000082(G1/S transition of mitotic cell cycle);GO:0000082(G1/S transition of mitotic cell cycle)","04390(Hippo signaling pathway);04392(Hippo signaling pathway - multiple species);04392(Hippo signaling pathway - multiple species)","K08791","EC:2.7.11.1","large tumor suppressor kinase 2 [Source:HGNC Symbol;Acc:HGNC:6515]",{"v":3.5431747400502,"d":"3.54"},{"v":1.37593804679096,"d":"1.38"},{"v":2.57509758401826,"d":"2.58"},{"v":1.3646271046499,"d":"1.36"},{"v":0.0997615795001216,"d":"0.10"},{"v":0.645978970277976,"d":"0.65"},"up","no"]
["MSTRG.13841","ZNHIT1","ENST00000485387;ENST00000305105;ENST00000461205;ENST00000492315","GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0005654(nucleoplasm);GO:0005515(protein binding);GO:0031491(nucleosome binding);GO:0042826(histone deacetylase binding);GO:0031063(regulation of histone deacetylation);GO:0043486(histone exchange);GO:0000812(Swr1 complex);GO:0000812(Swr1 complex)","NA","NA","NA","zinc finger HIT-type containing 1 [Source:HGNC Symbol;Acc:HGNC:21688]",{"v":2.77363936025408,"d":"2.77"},{"v":4.91197926878403,"d":"4.91"},{"v":0.564668376733744,"d":"0.56"},{"v":-0.824524256921961,"d":"-0.82"},{"v":0.099809712385291,"d":"0.10"},{"v":0.645978970277976,"d":"0.65"},"down","no"]
["MSTRG.1545","GATA3","ENST00000346208;ENST00000379328;ENST00000481743;ENST00000461472","GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0005634(nucleus);GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0005654(nucleoplasm);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0043565(sequence-specific DNA binding);GO:0005515(protein binding);GO:0007165(signal transduction);GO:0003713(transcription coactivator activity);GO:0045893(positive regulation of transcription, DNA-templated);GO:0002376(immune system process);GO:0045087(innate immune response);GO:0003682(chromatin binding);GO:0045582(positive regulation of T cell differentiation);GO:0000976(transcription regulatory region sequence-specific DNA binding);GO:0008285(negative regulation of cell proliferation);GO:0016579(protein deubiquitination);GO:1902036(regulation of hematopoietic stem cell differentiation);GO:0008584(male gonad development);GO:0009615(response to virus);GO:0005667(transcription factor complex);GO:0050728(negative regulation of inflammatory response);GO:0071356(cellular response to tumor necrosis factor);GO:0000977(RNA polymerase II regulatory region sequence-specific DNA binding);GO:0001228(transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding);GO:0032753(positive regulation of interleukin-4 production);GO:2000667(positive regulation of interleukin-13 secretion);GO:0044212(transcription regulatory region DNA binding);GO:0045786(negative regulation of cell cycle);GO:0045892(negative regulation of transcription, DNA-templated);GO:0000790(nuclear chromatin);GO:0006366(transcription from RNA polymerase II promoter);GO:0045599(negative regulation of fat cell differentiation);GO:0014065(phosphatidylinositol 3-kinase signaling);GO:0050852(T cell receptor signaling pathway);GO:0009653(anatomical structure morphogenesis);GO:2000352(negative regulation of endothelial cell apoptotic process);GO:0001709(cell fate determination);GO:0001046(core promoter sequence-specific DNA binding);GO:0070888(E-box binding);GO:0006952(defense response);GO:0043627(response to estrogen);GO:0010595(positive regulation of endothelial cell migration);GO:0051897(positive regulation of protein kinase B signaling);GO:0001078(transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0007596(blood coagulation);GO:0000987(core promoter proximal region sequence-specific DNA binding);GO:0001823(mesonephros development);GO:0060037(pharyngeal system development);GO:0008134(transcription factor binding);GO:0001822(kidney development);GO:0048485(sympathetic nervous system development);GO:2000611(positive regulation of thyroid hormone generation);GO:0071837(HMG box domain binding);GO:0042421(norepinephrine biosynthetic process);GO:2000146(negative regulation of cell motility);GO:0001085(RNA polymerase II transcription factor binding);GO:0035457(cellular response to interferon-alpha);GO:0071353(cellular response to interleukin-4);GO:0060231(mesenchymal to epithelial transition);GO:0031929(TOR signaling);GO:0000979(RNA polymerase II core promoter sequence-specific DNA binding);GO:0001071(nucleic acid binding transcription factor activity);GO:0001077(transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0001158(enhancer sequence-specific DNA binding);GO:0005134(interleukin-2 receptor binding);GO:0046983(protein dimerization activity);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0000902(cell morphogenesis);GO:0001701(in utero embryonic development);GO:0001764(neuron migration);GO:0001775(cell activation);GO:0001806(type IV hypersensitivity);GO:0001819(positive regulation of cytokine production);GO:0002088(lens development in camera-type eye);GO:0002572(pro-T cell differentiation);GO:0003180(aortic valve morphogenesis);GO:0003215(cardiac right ventricle morphogenesis);GO:0003281(ventricular septum development);GO:0006338(chromatin remodeling);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0006959(humoral immune response);GO:0007399(nervous system development);GO:0007411(axon guidance);GO:0009791(post-embryonic development);GO:0009967(positive regulation of signal transduction);GO:0010332(response to gamma radiation);GO:0010628(positive regulation of gene expression);GO:0010629(negative regulation of gene expression);GO:0010975(regulation of neuron projection development);GO:0030182(neuron differentiation);GO:0030217(T cell differentiation);GO:0030218(erythrocyte differentiation);GO:0032689(negative regulation of interferon-gamma production);GO:0032703(negative regulation of interleukin-2 production);GO:0032736(positive regulation of interleukin-13 production);GO:0032754(positive regulation of interleukin-5 production);GO:0033077(T cell differentiation in thymus);GO:0033600(negative regulation of mammary gland epithelial cell proliferation);GO:0035162(embryonic hemopoiesis);GO:0035799(ureter maturation);GO:0035898(parathyroid hormone secretion);GO:0042035(regulation of cytokine biosynthetic process);GO:0042472(inner ear morphogenesis);GO:0042493(response to drug);GO:0043370(regulation of CD4-positive, alpha-beta T cell differentiation);GO:0043523(regulation of neuron apoptotic process);GO:0043583(ear development);GO:0045061(thymic T cell selection);GO:0045064(T-helper 2 cell differentiation);GO:0045471(response to ethanol);GO:0045597(positive regulation of cell differentiation);GO:0048469(cell maturation);GO:0048538(thymus development);GO:0048568(embryonic organ development);GO:0048589(developmental growth);GO:0048646(anatomical structure formation involved in morphogenesis);GO:0048872(homeostasis of number of cells);GO:0051569(regulation of histone H3-K4 methylation);GO:0060017(parathyroid gland development);GO:0060065(uterus development);GO:0060374(mast cell differentiation);GO:0060676(ureteric bud formation);GO:0061085(regulation of histone H3-K27 methylation);GO:0061290(canonical Wnt signaling pathway involved in metanephric kidney development);GO:0071345(cellular response to cytokine stimulus);GO:0071442(positive regulation of histone H3-K14 acetylation);GO:0071599(otic vesicle development);GO:0071773(cellular response to BMP stimulus);GO:0072001(renal system development);GO:0072107(positive regulation of ureteric bud formation);GO:0072178(nephric duct morphogenesis);GO:0072179(nephric duct formation);GO:0072182(regulation of nephron tubule epithelial cell differentiation);GO:0072602(interleukin-4 secretion);GO:0072643(interferon-gamma secretion);GO:0072676(lymphocyte migration);GO:0090102(cochlea development);GO:1901536(negative regulation of DNA demethylation);GO:2000114(regulation of establishment of cell polarity);GO:2000553(positive regulation of T-helper 2 cell cytokine production);GO:2000607(negative regulation of cell proliferation involved in mesonephros development);GO:2000617(positive regulation of histone H3-K9 acetylation);GO:2000664(positive regulation of interleukin-5 secretion);GO:2000679(positive regulation of transcription regulatory region DNA binding);GO:2000683(regulation of cellular response to X-ray);GO:2000703(negative regulation of fibroblast growth factor receptor signaling pathway involved in ureteric bud formation);GO:2000734(negative regulation of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation);GO:2000734(negative regulation of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation)","04658(Th1 and Th2 cell differentiation);04659(Th17 cell differentiation);05321(Inflammatiory bowel disease (IBD));05321(Inflammatiory bowel disease (IBD))","K17895","NA","GATA binding protein 3 [Source:HGNC Symbol;Acc:HGNC:4172]",{"v":4.38651986351061,"d":"4.39"},{"v":1.69756159299109,"d":"1.70"},{"v":2.5840121982152,"d":"2.58"},{"v":1.36961288050515,"d":"1.37"},{"v":0.0998434901088364,"d":"0.10"},{"v":0.645978970277976,"d":"0.65"},"up","no"]
["MSTRG.1916","NDUFB8;AL133352.1;SEC31B","ENST00000466088;ENST00000299166;ENST00000370322;ENST00000529437;ENST00000529568;ENST00000528425;ENST00000482456;ENST00000498298;ENST00000370345;ENST00000528174;ENST00000464651;ENST00000531189;ENST00000462434;ENST00000479697;ENST00000484848;ENST00000490567;ENST00000370320;ENST00000469824;ENST00000485800;ENST00000533549;ENST00000492667;ENST00000469546;ENST00000531418","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0055114(oxidation-reduction process);GO:0005739(mitochondrion);GO:0005743(mitochondrial inner membrane);GO:0005747(mitochondrial respiratory chain complex I);GO:0006120(mitochondrial electron transport, NADH to ubiquinone);GO:0070469(respiratory chain);GO:0008137(NADH dehydrogenase (ubiquinone) activity);GO:0003954(NADH dehydrogenase activity);GO:0032981(mitochondrial respiratory chain complex I assembly);GO:0005783(endoplasmic reticulum);GO:0006810(transport);GO:0005737(cytoplasm);GO:0015031(protein transport);GO:0005789(endoplasmic reticulum membrane);GO:0031410(cytoplasmic vesicle);GO:0016192(vesicle-mediated transport);GO:0012507(ER to Golgi transport vesicle membrane);GO:0030120(vesicle coat);GO:0005783(endoplasmic reticulum)","00190(Oxidative phosphorylation);04723(Retrograde endocannabinoid signaling);05010(Alzheimer's disease);05012(Parkinson's disease);05016(Huntington's disease);04932(Non-alcoholic fatty liver disease (NAFLD));04141(Protein processing in endoplasmic reticulum);04932(Non-alcoholic fatty liver disease (NAFLD))","K03964;K14005","NA","NADH:ubiquinone oxidoreductase subunit B8 [Source:HGNC Symbol;Acc:HGNC:7703];SEC31 homolog B, COPII coat complex component [Source:HGNC Symbol;Acc:HGNC:23197]",{"v":2.43399305102144,"d":"2.43"},{"v":4.31028670916776,"d":"4.31"},{"v":0.564694001873347,"d":"0.56"},{"v":-0.824458787658005,"d":"-0.82"},{"v":0.0998477784938402,"d":"0.10"},{"v":0.645978970277976,"d":"0.65"},"down","no"]
["MSTRG.11138","DTX3L","ENST00000296161","GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0016740(transferase activity);GO:0016569(covalent chromatin modification);GO:0016567(protein ubiquitination);GO:0005515(protein binding);GO:0006281(DNA repair);GO:0006974(cellular response to DNA damage stimulus);GO:0000209(protein polyubiquitination);GO:0042393(histone binding);GO:0004842(ubiquitin-protein transferase activity);GO:0006302(double-strand break repair);GO:0010390(histone monoubiquitination)","04330(Notch signaling pathway)","K06058","EC:2.3.2.27","deltex E3 ubiquitin ligase 3L [Source:HGNC Symbol;Acc:HGNC:30323]",{"v":19.162142,"d":"19.16"},{"v":7.476229,"d":"7.48"},{"v":2.56307585013782,"d":"2.56"},{"v":1.3578761735177,"d":"1.36"},{"v":0.0999790604221248,"d":"0.10"},{"v":0.646091323314615,"d":"0.65"},"up","no"]
["ENSG00000122873","CISD1","ENST00000333926;ENST00000464703;ENST00000488388","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0046872(metal ion binding);GO:0005739(mitochondrion);GO:0051537(2 iron, 2 sulfur cluster binding);GO:0043457(regulation of cellular respiration);GO:0005741(mitochondrial outer membrane);GO:0043231(intracellular membrane-bounded organelle);GO:0051536(iron-sulfur cluster binding);GO:0070062(extracellular exosome);GO:0070062(extracellular exosome)","NA","NA","NA","CDGSH iron sulfur domain 1 [Source:HGNC Symbol;Acc:HGNC:30880]",{"v":0.71180207980399,"d":"0.71"},{"v":1.28306814630732,"d":"1.28"},{"v":0.554765607619955,"d":"0.55"},{"v":-0.850049743516608,"d":"-0.85"},{"v":0.099996555314321,"d":"0.10"},{"v":0.646091323314615,"d":"0.65"},"down","no"]
["ENSG00000169914","OTUD3","ENST00000375120;ENST00000466697;ENST00000481686","GO:0016787(hydrolase activity);GO:0008233(peptidase activity);GO:0008234(cysteine-type peptidase activity);GO:0006508(proteolysis);GO:0036459(thiol-dependent ubiquitinyl hydrolase activity);GO:0005829(cytosol);GO:0016579(protein deubiquitination);GO:0004843(thiol-dependent ubiquitin-specific protease activity);GO:0005737(cytoplasm);GO:0035871(protein K11-linked deubiquitination);GO:0051898(negative regulation of protein kinase B signaling);GO:0050821(protein stabilization);GO:0044313(protein K6-linked deubiquitination);GO:0071108(protein K48-linked deubiquitination);GO:1990167(protein K27-linked deubiquitination);GO:1990167(protein K27-linked deubiquitination)","NA","NA","NA","OTU deubiquitinase 3 [Source:HGNC Symbol;Acc:HGNC:29038]",{"v":1.22805511260529,"d":"1.23"},{"v":0.473938576474065,"d":"0.47"},{"v":2.59116934886707,"d":"2.59"},{"v":1.37360330760086,"d":"1.37"},{"v":0.100032050229887,"d":"0.10"},{"v":0.646091323314615,"d":"0.65"},"up","no"]
["MSTRG.6418","RANGRF","ENST00000226105;ENST00000407006;ENST00000578849;ENST00000580434;ENST00000580777;ENST00000439238","GO:0005737(cytoplasm);GO:0005634(nucleus);GO:0002027(regulation of heart rate);GO:0006810(transport);GO:0015031(protein transport);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0005085(guanyl-nucleotide exchange factor activity);GO:0017080(sodium channel regulator activity);GO:0044325(ion channel binding);GO:2000649(regulation of sodium ion transmembrane transporter activity);GO:0043547(positive regulation of GTPase activity);GO:0005886(plasma membrane);GO:0042391(regulation of membrane potential);GO:0090004(positive regulation of establishment of protein localization to plasma membrane);GO:0005901(caveola);GO:0014704(intercalated disc);GO:2000010(positive regulation of protein localization to cell surface);GO:0006888(ER to Golgi vesicle-mediated transport);GO:0098909(regulation of cardiac muscle cell action potential involved in regulation of contraction);GO:1902305(regulation of sodium ion transmembrane transport);GO:0098905(regulation of bundle of His cell action potential);GO:1900825(regulation of membrane depolarization during cardiac muscle cell action potential);GO:0003254(regulation of membrane depolarization);GO:0008536(Ran GTPase binding);GO:0005087(Ran guanyl-nucleotide exchange factor activity);GO:0008565(protein transporter activity);GO:0032527(protein exit from endoplasmic reticulum);GO:0005791(rough endoplasmic reticulum);GO:0005791(rough endoplasmic reticulum)","NA","NA","NA","RAN guanine nucleotide release factor [Source:HGNC Symbol;Acc:HGNC:17679]",{"v":3.59445145529486,"d":"3.59"},{"v":6.40167546353836,"d":"6.40"},{"v":0.561486047796013,"d":"0.56"},{"v":-0.832677920926824,"d":"-0.83"},{"v":0.100098559918001,"d":"0.10"},{"v":0.646161521027098,"d":"0.65"},"down","no"]
["MSTRG.15167","HCCS","ENST00000380762;ENST00000380763;ENST00000321143","GO:0016020(membrane);GO:0046872(metal ion binding);GO:0005739(mitochondrion);GO:0005743(mitochondrial inner membrane);GO:0016829(lyase activity);GO:0004408(holocytochrome-c synthase activity);GO:0009887(animal organ morphogenesis);GO:0055114(oxidation-reduction process);GO:0018063(cytochrome c-heme linkage);GO:0018063(cytochrome c-heme linkage)","00860(Porphyrin and chlorophyll metabolism);00860(Porphyrin and chlorophyll metabolism)","K01764","EC:4.4.1.17","holocytochrome c synthase [Source:HGNC Symbol;Acc:HGNC:4837]",{"v":2.16424106937902,"d":"2.16"},{"v":3.84838852847966,"d":"3.85"},{"v":0.562375927836481,"d":"0.56"},{"v":-0.830393252849236,"d":"-0.83"},{"v":0.100274918794211,"d":"0.10"},{"v":0.646588427462338,"d":"0.65"},"down","no"]
["MSTRG.14061","AC245088.2","ENST00000634605","NA","NA","NA","NA",null,{"v":8.470561,"d":"8.47"},{"v":15.095436,"d":"15.10"},{"v":0.561133908288571,"d":"0.56"},{"v":-0.833583000041078,"d":"-0.83"},{"v":0.10027604907084,"d":"0.10"},{"v":0.646588427462338,"d":"0.65"},"down","no"]
["MSTRG.11744","ADH5","ENST00000296412;ENST00000503130;ENST00000512621;ENST00000512659;ENST00000505652;ENST00000508511;ENST00000512991;ENST00000507102;ENST00000512604;ENST00000508146;ENST00000502386;ENST00000626055","GO:0005737(cytoplasm);GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0006069(ethanol oxidation);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0051775(response to redox state);GO:0009055(electron carrier activity);GO:0005504(fatty acid binding);GO:0004022(alcohol dehydrogenase (NAD) activity);GO:0018467(formaldehyde dehydrogenase activity);GO:0042803(protein homodimerization activity);GO:0051903(S-(hydroxymethyl)glutathione dehydrogenase activity);GO:0001523(retinoid metabolic process);GO:0003016(respiratory system process);GO:0018119(peptidyl-cysteine S-nitrosylation);GO:0032496(response to lipopolysaccharide);GO:0045777(positive regulation of blood pressure);GO:0046294(formaldehyde catabolic process);GO:0051409(response to nitrosative stress);GO:0005739(mitochondrion);GO:0005739(mitochondrion)","00010(Glycolysis / Gluconeogenesis);00071(Fatty acid degradation);00350(Tyrosine metabolism);00830(Retinol metabolism);00980(Metabolism of xenobiotics by cytochrome P450);00982(Drug metabolism - cytochrome P450);05204(Chemical carcinogenesis);05204(Chemical carcinogenesis)","K00121","EC:1.1.1.284;EC:1.1.1.1","alcohol dehydrogenase 5 (class III), chi polypeptide [Source:HGNC Symbol;Acc:HGNC:253]",{"v":4.92731183662145,"d":"4.93"},{"v":8.69969557603781,"d":"8.70"},{"v":0.566377500632677,"d":"0.57"},{"v":-0.820164139442412,"d":"-0.82"},{"v":0.100398234175938,"d":"0.10"},{"v":0.646763240203187,"d":"0.65"},"down","no"]
["ENSG00000119522","DENND1A","ENST00000373624;ENST00000373620;ENST00000491650;ENST00000373618;ENST00000475421;ENST00000474676;ENST00000462245;ENST00000473039;ENST00000394215;ENST00000479305;ENST00000497135","GO:0006810(transport);GO:0016020(membrane);GO:0015031(protein transport);GO:0043231(intracellular membrane-bounded organelle);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0005886(plasma membrane);GO:0030054(cell junction);GO:0045202(synapse);GO:0031410(cytoplasmic vesicle);GO:0005085(guanyl-nucleotide exchange factor activity);GO:0008289(lipid binding);GO:0006897(endocytosis);GO:0032266(phosphatidylinositol-3-phosphate binding);GO:0017112(Rab guanyl-nucleotide exchange factor activity);GO:0061024(membrane organization);GO:0030665(clathrin-coated vesicle membrane);GO:0030136(clathrin-coated vesicle);GO:0042734(presynaptic membrane);GO:0032483(regulation of Rab protein signal transduction);GO:0032456(endocytic recycling);GO:0017124(SH3 domain binding);GO:0017137(Rab GTPase binding);GO:1901981(phosphatidylinositol phosphate binding);GO:0043547(positive regulation of GTPase activity);GO:0048488(synaptic vesicle endocytosis);GO:0030425(dendrite);GO:0043025(neuronal cell body);GO:0043025(neuronal cell body)","NA","NA","NA","DENN domain containing 1A [Source:HGNC Symbol;Acc:HGNC:29324]",{"v":3.19135405128705,"d":"3.19"},{"v":1.23975256484009,"d":"1.24"},{"v":2.57418628667946,"d":"2.57"},{"v":1.36411646115142,"d":"1.36"},{"v":0.10041454594733,"d":"0.10"},{"v":0.646763240203187,"d":"0.65"},"up","no"]
["MSTRG.6518","NATD1","ENST00000611551","GO:0005515(protein binding)","NA","NA","NA","N-acetyltransferase domain containing 1 [Source:HGNC Symbol;Acc:HGNC:30770]",{"v":15.844939,"d":"15.84"},{"v":6.187997,"d":"6.19"},{"v":2.56059254715217,"d":"2.56"},{"v":1.35647770316203,"d":"1.36"},{"v":0.100597213760051,"d":"0.10"},{"v":0.64730192128267,"d":"0.65"},"up","no"]
["MSTRG.14680","KIAA2026","ENST00000399933;ENST00000436015;ENST00000381461;ENST00000540714;ENST00000443149","NA","NA","NA","NA","KIAA2026 [Source:HGNC Symbol;Acc:HGNC:23378]",{"v":4.34645216267339,"d":"4.35"},{"v":1.69382965725095,"d":"1.69"},{"v":2.56605033691971,"d":"2.57"},{"v":1.35954947132867,"d":"1.36"},{"v":0.100807321965365,"d":"0.10"},{"v":0.64730192128267,"d":"0.65"},"up","no"]
["MSTRG.13339","TAB2;AL031056.1","MSTRG.13339.8;ENST00000637181;ENST00000461481;ENST00000635954;ENST00000470466;ENST00000451095;ENST00000606202;ENST00000636456;ENST00000484505;ENST00000538427","GO:0046872(metal ion binding);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005829(cytosol);GO:0005515(protein binding);GO:0038095(Fc-epsilon receptor signaling pathway);GO:0005886(plasma membrane);GO:0005654(nucleoplasm);GO:0007507(heart development);GO:0010008(endosome membrane);GO:0002223(stimulatory C-type lectin receptor signaling pathway);GO:0050852(T cell receptor signaling pathway);GO:0010507(negative regulation of autophagy);GO:0043123(positive regulation of I-kappaB kinase/NF-kappaB signaling);GO:0002755(MyD88-dependent toll-like receptor signaling pathway);GO:0007249(I-kappaB kinase/NF-kappaB signaling);GO:0007254(JNK cascade);GO:0051092(positive regulation of NF-kappaB transcription factor activity);GO:0070423(nucleotide-binding oligomerization domain containing signaling pathway);GO:0045860(positive regulation of protein kinase activity);GO:0000187(activation of MAPK activity);GO:0070530(K63-linked polyubiquitin binding);GO:0070530(K63-linked polyubiquitin binding)","04010(MAPK signaling pathway);04064(NF-kappa B signaling pathway);04668(TNF signaling pathway);04620(Toll-like receptor signaling pathway);04621(NOD-like receptor signaling pathway);04657(IL-17 signaling pathway);04380(Osteoclast differentiation);05162(Measles);05168(Herpes simplex infection);05169(Epstein-Barr virus infection);05145(Toxoplasmosis);05140(Leishmaniasis);05140(Leishmaniasis)","K04404","NA","TGF-beta activated kinase 1/MAP3K7 binding protein 2 [Source:HGNC Symbol;Acc:HGNC:17075]",{"v":14.8183581909018,"d":"14.82"},{"v":5.7942283537298,"d":"5.79"},{"v":2.55743427532729,"d":"2.56"},{"v":1.35469716396756,"d":"1.35"},{"v":0.100875733420766,"d":"0.10"},{"v":0.64730192128267,"d":"0.65"},"up","no"]
["ENSG00000185760","KCNQ5","ENST00000342056;ENST00000355635;ENST00000443915","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0055085(transmembrane transport);GO:0005216(ion channel activity);GO:0006811(ion transport);GO:0005244(voltage-gated ion channel activity);GO:0005249(voltage-gated potassium channel activity);GO:0005267(potassium channel activity);GO:0006813(potassium ion transport);GO:0034765(regulation of ion transmembrane transport);GO:0071805(potassium ion transmembrane transport);GO:0008076(voltage-gated potassium channel complex);GO:0005886(plasma membrane);GO:0005887(integral component of plasma membrane);GO:0005515(protein binding);GO:0030118(clathrin coat);GO:0030118(clathrin coat)","04725(Cholinergic synapse);04725(Cholinergic synapse)","K04930","NA","potassium voltage-gated channel subfamily Q member 5 [Source:HGNC Symbol;Acc:HGNC:6299]",{"v":0.34150942351387,"d":"0.34"},{"v":0.127033114002642,"d":"0.13"},{"v":2.68834961809066,"d":"2.69"},{"v":1.42672077185411,"d":"1.43"},{"v":0.100895292339569,"d":"0.10"},{"v":0.64730192128267,"d":"0.65"},"up","no"]
["MSTRG.3058","ACRBP","MSTRG.3058.1;MSTRG.3058.2;MSTRG.3058.3;ENST00000540513;ENST00000542357;ENST00000229243;ENST00000546114;ENST00000536350;ENST00000544352;ENST00000538524","GO:0005634(nucleus);GO:0005576(extracellular region);GO:0031410(cytoplasmic vesicle);GO:0001669(acrosomal vesicle);GO:0003674(molecular_function);GO:0008150(biological_process);GO:0002080(acrosomal membrane);GO:0048240(sperm capacitation);GO:0048240(sperm capacitation)","NA","NA","NA","acrosin binding protein [Source:HGNC Symbol;Acc:HGNC:17195]",{"v":7.84120972956361,"d":"7.84"},{"v":13.8242560697603,"d":"13.82"},{"v":0.567206632313168,"d":"0.57"},{"v":-0.818053692864631,"d":"-0.82"},{"v":0.101022982473305,"d":"0.10"},{"v":0.64730192128267,"d":"0.65"},"down","no"]
["MSTRG.2237","AMPD3","ENST00000528723;ENST00000396554;ENST00000533116;ENST00000444303;ENST00000534047;ENST00000396553;ENST00000529507;ENST00000530864;ENST00000529834;ENST00000531227","GO:0003876(AMP deaminase activity);GO:0032264(IMP salvage);GO:0046872(metal ion binding);GO:0016787(hydrolase activity);GO:0019239(deaminase activity);GO:0009168(purine ribonucleoside monophosphate biosynthetic process);GO:0005515(protein binding);GO:0009117(nucleotide metabolic process);GO:0005576(extracellular region);GO:0005829(cytosol);GO:0043312(neutrophil degranulation);GO:0034774(secretory granule lumen);GO:1904813(ficolin-1-rich granule lumen);GO:0043101(purine-containing compound salvage);GO:0006188(IMP biosynthetic process);GO:0006196(AMP catabolic process);GO:0034101(erythrocyte homeostasis);GO:0046031(ADP metabolic process);GO:0046033(AMP metabolic process);GO:0046034(ATP metabolic process);GO:0046039(GTP metabolic process);GO:0097009(energy homeostasis);GO:0097009(energy homeostasis)","00230(Purine metabolism);00230(Purine metabolism)","K01490","EC:3.5.4.6","adenosine monophosphate deaminase 3 [Source:HGNC Symbol;Acc:HGNC:470]",{"v":3.78531373001619,"d":"3.79"},{"v":1.47560190019137,"d":"1.48"},{"v":2.5652675898054,"d":"2.57"},{"v":1.35910932499396,"d":"1.36"},{"v":0.101047553250963,"d":"0.10"},{"v":0.64730192128267,"d":"0.65"},"up","no"]
["MSTRG.12153","TBCA","ENST00000380377;ENST00000518338;ENST00000520039;ENST00000306388;ENST00000517679;ENST00000517881;ENST00000518218;ENST00000520361;ENST00000522370","GO:0003723(RNA binding);GO:0005737(cytoplasm);GO:0005730(nucleolus);GO:0015630(microtubule cytoskeleton);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0005874(microtubule);GO:0070062(extracellular exosome);GO:0006457(protein folding);GO:0048487(beta-tubulin binding);GO:0007021(tubulin complex assembly);GO:0007023(post-chaperonin tubulin folding pathway);GO:0051087(chaperone binding);GO:0051087(chaperone binding)","NA","NA","NA","tubulin folding cofactor A [Source:HGNC Symbol;Acc:HGNC:11579]",{"v":5.10454122171354,"d":"5.10"},{"v":9.02322108109876,"d":"9.02"},{"v":0.565711642864009,"d":"0.57"},{"v":-0.821861231614148,"d":"-0.82"},{"v":0.101125387222282,"d":"0.10"},{"v":0.64730192128267,"d":"0.65"},"down","no"]
["MSTRG.12674","MAK","ENST00000536370;ENST00000313243;ENST00000538030;ENST00000474039;ENST00000354489","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0005856(cytoskeleton);GO:0042995(cell projection);GO:0005515(protein binding);GO:0007275(multicellular organism development);GO:0030154(cell differentiation);GO:0003713(transcription coactivator activity);GO:0007283(spermatogenesis);GO:0005813(centrosome);GO:0005815(microtubule organizing center);GO:0005819(spindle);GO:0030496(midbody);GO:0035556(intracellular signal transduction);GO:0005929(cilium);GO:0060271(cilium assembly);GO:0001750(photoreceptor outer segment);GO:0010468(regulation of gene expression);GO:0045494(photoreceptor cell maintenance);GO:0001917(photoreceptor inner segment);GO:0046777(protein autophosphorylation);GO:0072686(mitotic spindle);GO:0042073(intraciliary transport);GO:0042073(intraciliary transport)","NA","NA","NA","male germ cell associated kinase [Source:HGNC Symbol;Acc:HGNC:6816]",{"v":2.94629570728822,"d":"2.95"},{"v":1.14272933980123,"d":"1.14"},{"v":2.57829706884109,"d":"2.58"},{"v":1.36641849917382,"d":"1.37"},{"v":0.101154985659224,"d":"0.10"},{"v":0.64730192128267,"d":"0.65"},"up","no"]
["ENSG00000067221","STOML1","ENST00000541638;ENST00000563229;ENST00000567876;ENST00000565240;ENST00000564777;ENST00000359750;ENST00000316900;ENST00000567052;ENST00000561480","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005515(protein binding);GO:0003674(molecular_function);GO:0008150(biological_process);GO:0005575(cellular_component);GO:0005575(cellular_component)","NA","NA","NA","stomatin like 1 [Source:HGNC Symbol;Acc:HGNC:14560]",{"v":0.167112608259249,"d":"0.17"},{"v":0.303145952299015,"d":"0.30"},{"v":0.551261222496593,"d":"0.55"},{"v":-0.859191973740329,"d":"-0.86"},{"v":0.101196555241716,"d":"0.10"},{"v":0.64730192128267,"d":"0.65"},"down","no"]
["MSTRG.2673","FAM168A","ENST00000356467;ENST00000632101;ENST00000432223;ENST00000064778","GO:0005515(protein binding);GO:1905053(positive regulation of base-excision repair);GO:1905053(positive regulation of base-excision repair)","NA","NA","NA","family with sequence similarity 168 member A [Source:HGNC Symbol;Acc:HGNC:28999]",{"v":1.16264419170787,"d":"1.16"},{"v":0.450165851020667,"d":"0.45"},{"v":2.58270188436504,"d":"2.58"},{"v":1.36888112593002,"d":"1.37"},{"v":0.101197634214818,"d":"0.10"},{"v":0.64730192128267,"d":"0.65"},"up","no"]
["ENSG00000089057","SLC23A2","ENST00000338244;ENST00000496331;ENST00000468355;ENST00000423430;ENST00000379333","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005215(transporter activity);GO:0055085(transmembrane transport);GO:0015293(symporter activity);GO:0006811(ion transport);GO:0005886(plasma membrane);GO:0006814(sodium ion transport);GO:0070890(sodium-dependent L-ascorbate transmembrane transporter activity);GO:0015882(L-ascorbic acid transport);GO:0035461(vitamin transmembrane transport);GO:1905039(carboxylic acid transmembrane transport);GO:0016323(basolateral plasma membrane);GO:0005887(integral component of plasma membrane);GO:0006139(nucleobase-containing compound metabolic process);GO:0016324(apical plasma membrane);GO:0019852(L-ascorbic acid metabolic process);GO:0015993(molecular hydrogen transport);GO:0008523(sodium-dependent multivitamin transmembrane transporter activity);GO:0015205(nucleobase transmembrane transporter activity);GO:0015229(L-ascorbic acid transporter activity);GO:0015851(nucleobase transport);GO:0070904(transepithelial L-ascorbic acid transport);GO:0008520(L-ascorbate:sodium symporter activity);GO:0006979(response to oxidative stress);GO:0005737(cytoplasm);GO:0009925(basal plasma membrane);GO:0009925(basal plasma membrane)","NA","NA","NA","solute carrier family 23 member 2 [Source:HGNC Symbol;Acc:HGNC:10973]",{"v":4.03890747278776,"d":"4.04"},{"v":1.57613849647372,"d":"1.58"},{"v":2.56253335720431,"d":"2.56"},{"v":1.35757078470004,"d":"1.36"},{"v":0.101205069368829,"d":"0.10"},{"v":0.64730192128267,"d":"0.65"},"up","no"]
["MSTRG.15335","MSN","MSTRG.15335.7;MSTRG.15335.1;ENST00000360270;ENST00000609672;ENST00000439474;ENST00000447323;ENST00000429601;ENST00000609205","GO:0005856(cytoskeleton);GO:0008092(cytoskeletal protein binding);GO:0045177(apical part of cell);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005829(cytosol);GO:0003779(actin binding);GO:0005886(plasma membrane);GO:0042995(cell projection);GO:0005515(protein binding);GO:0007010(cytoskeleton organization);GO:0048471(perinuclear region of cytoplasm);GO:0005615(extracellular space);GO:0005925(focal adhesion);GO:0030175(filopodium);GO:0070062(extracellular exosome);GO:0019901(protein kinase binding);GO:0010628(positive regulation of gene expression);GO:0071944(cell periphery);GO:0072562(blood microparticle);GO:0071437(invadopodium);GO:0005102(receptor binding);GO:0072678(T cell migration);GO:0008360(regulation of cell shape);GO:0016324(apical plasma membrane);GO:0035722(interleukin-12-mediated signaling pathway);GO:0005200(structural constituent of cytoskeleton);GO:0031982(vesicle);GO:0061028(establishment of endothelial barrier);GO:0031528(microvillus membrane);GO:0008361(regulation of cell size);GO:0022612(gland morphogenesis);GO:0045198(establishment of epithelial cell apical/basal polarity);GO:0006928(movement of cell or subcellular component);GO:0003725(double-stranded RNA binding);GO:0042098(T cell proliferation);GO:0031143(pseudopodium);GO:0071394(cellular response to testosterone stimulus);GO:2000401(regulation of lymphocyte migration);GO:0019899(enzyme binding);GO:0005902(microvillus);GO:0050839(cell adhesion molecule binding);GO:0007159(leukocyte cell-cell adhesion);GO:0022614(membrane to membrane docking);GO:0050900(leukocyte migration);GO:0009986(cell surface);GO:0001771(immunological synapse formation);GO:1902115(regulation of organelle assembly);GO:1902966(positive regulation of protein localization to early endosome);GO:1903364(positive regulation of cellular protein catabolic process);GO:2000643(positive regulation of early endosome to late endosome transport);GO:0070489(T cell aggregation);GO:0071803(positive regulation of podosome assembly);GO:0001931(uropod);GO:0016323(basolateral plasma membrane);GO:0043209(myelin sheath);GO:0043209(myelin sheath)","04530(Tight junction);04810(Regulation of actin cytoskeleton);04670(Leukocyte transendothelial migration);05205(Proteoglycans in cancer);05162(Measles);05162(Measles)","K05763","NA","moesin [Source:HGNC Symbol;Acc:HGNC:7373]",{"v":98.1749456053257,"d":"98.17"},{"v":172.511208449675,"d":"172.51"},{"v":0.569093141759339,"d":"0.57"},{"v":-0.8132633014815,"d":"-0.81"},{"v":0.101357832308755,"d":"0.10"},{"v":0.64730192128267,"d":"0.65"},"down","no"]
["MSTRG.12708","TDP2","ENST00000378198;ENST00000478507;ENST00000480495;ENST00000341060;ENST00000478285","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0005654(nucleoplasm);GO:0016787(hydrolase activity);GO:0090305(nucleic acid phosphodiester bond hydrolysis);GO:0016235(aggresome);GO:0006281(DNA repair);GO:0006974(cellular response to DNA damage stimulus);GO:0016604(nuclear body);GO:0000287(magnesium ion binding);GO:0004518(nuclease activity);GO:0005730(nucleolus);GO:1903507(negative regulation of nucleic acid-templated transcription);GO:0005515(protein binding);GO:0048666(neuron development);GO:0007166(cell surface receptor signaling pathway);GO:0003714(transcription corepressor activity);GO:0016605(PML body);GO:0003697(single-stranded DNA binding);GO:0006302(double-strand break repair);GO:0030145(manganese ion binding);GO:0036317(tyrosyl-RNA phosphodiesterase activity);GO:0070260(5'-tyrosyl-DNA phosphodiesterase activity);GO:0070260(5'-tyrosyl-DNA phosphodiesterase activity)","NA","NA","NA","tyrosyl-DNA phosphodiesterase 2 [Source:HGNC Symbol;Acc:HGNC:17768]",{"v":14.7341909279689,"d":"14.73"},{"v":25.9170400217391,"d":"25.92"},{"v":0.568513646450749,"d":"0.57"},{"v":-0.814733115285176,"d":"-0.81"},{"v":0.101385794994869,"d":"0.10"},{"v":0.64730192128267,"d":"0.65"},"down","no"]
["MSTRG.7913","BRD4","ENST00000371835;ENST00000601941;ENST00000630599;ENST00000594066;ENST00000595926;ENST00000360016;ENST00000601071;ENST00000594842;ENST00000602230;ENST00000597315;MSTRG.7913.2;ENST00000263377;ENST00000594841","GO:0005634(nucleus);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0016569(covalent chromatin modification);GO:0005694(chromosome);GO:0005515(protein binding);GO:0006974(cellular response to DNA damage stimulus);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0003682(chromatin binding);GO:0016032(viral process);GO:0043123(positive regulation of I-kappaB kinase/NF-kappaB signaling);GO:0002039(p53 binding);GO:0070577(lysine-acetylated histone binding);GO:0000993(RNA polymerase II core binding);GO:0000083(regulation of transcription involved in G1/S transition of mitotic cell cycle);GO:0010971(positive regulation of G2/M transition of mitotic cell cycle);GO:0032968(positive regulation of transcription elongation from RNA polymerase II promoter);GO:0050727(regulation of inflammatory response);GO:1901407(regulation of phosphorylation of RNA polymerase II C-terminal domain);GO:0000794(condensed nuclear chromosome);GO:0000794(condensed nuclear chromosome)","NA","NA","NA","bromodomain containing 4 [Source:HGNC Symbol;Acc:HGNC:13575]",{"v":5.2632431240387,"d":"5.26"},{"v":2.05632477945919,"d":"2.06"},{"v":2.55953883190715,"d":"2.56"},{"v":1.35588389426635,"d":"1.36"},{"v":0.101454569539909,"d":"0.10"},{"v":0.64730192128267,"d":"0.65"},"up","no"]
["ENSG00000125733","TRIP10","ENST00000313244;ENST00000600428;ENST00000595305;ENST00000595319;ENST00000313285;ENST00000600491;ENST00000596078;ENST00000596543","GO:0043231(intracellular membrane-bounded organelle);GO:0005654(nucleoplasm);GO:0006897(endocytosis);GO:0030036(actin cytoskeleton organization);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005794(Golgi apparatus);GO:0005886(plasma membrane);GO:0043547(positive regulation of GTPase activity);GO:0005856(cytoskeleton);GO:0042995(cell projection);GO:0005515(protein binding);GO:0048471(perinuclear region of cytoplasm);GO:0005764(lysosome);GO:0042802(identical protein binding);GO:0008289(lipid binding);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0005096(GTPase activator activity);GO:0051056(regulation of small GTPase mediated signal transduction);GO:0001891(phagocytic cup);GO:0061024(membrane organization);GO:0005938(cell cortex);GO:0007165(signal transduction);GO:0007154(cell communication);GO:0007154(cell communication)","04910(Insulin signaling pathway);04910(Insulin signaling pathway)","K07196","NA","thyroid hormone receptor interactor 10 [Source:HGNC Symbol;Acc:HGNC:12304]",{"v":0.28971520441989,"d":"0.29"},{"v":0.54129764816675,"d":"0.54"},{"v":0.535223467903636,"d":"0.54"},{"v":-0.901786719778838,"d":"-0.90"},{"v":0.101457113789122,"d":"0.10"},{"v":0.64730192128267,"d":"0.65"},"down","no"]
["ENSG00000112715","VEGFA","ENST00000372067;ENST00000520948;ENST00000611736;ENST00000512683;ENST00000523950;ENST00000520265;ENST00000497139;ENST00000480614;ENST00000493786;ENST00000372064;ENST00000621747;ENST00000425836;ENST00000640499;ENST00000615393;ENST00000372077;ENST00000230480","GO:0016020(membrane);GO:0008083(growth factor activity);GO:0008201(heparin binding);GO:0005615(extracellular space);GO:0045766(positive regulation of angiogenesis);GO:0008284(positive regulation of cell proliferation);GO:0010595(positive regulation of endothelial cell migration);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0003151(outflow tract morphogenesis);GO:0030335(positive regulation of cell migration);GO:0008360(regulation of cell shape);GO:0043536(positive regulation of blood vessel endothelial cell migration);GO:0005737(cytoplasm);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0007275(multicellular organism development);GO:0005578(proteinaceous extracellular matrix);GO:0007399(nervous system development);GO:0030154(cell differentiation);GO:0042802(identical protein binding);GO:0001934(positive regulation of protein phosphorylation);GO:0010628(positive regulation of gene expression);GO:0061418(regulation of transcription from RNA polymerase II promoter in response to hypoxia);GO:0001666(response to hypoxia);GO:0042803(protein homodimerization activity);GO:0009986(cell surface);GO:0033138(positive regulation of peptidyl-serine phosphorylation);GO:0043066(negative regulation of apoptotic process);GO:0050731(positive regulation of peptidyl-tyrosine phosphorylation);GO:0001938(positive regulation of endothelial cell proliferation);GO:0002576(platelet degranulation);GO:0045785(positive regulation of cell adhesion);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0031093(platelet alpha granule lumen);GO:0048010(vascular endothelial growth factor receptor signaling pathway);GO:0001525(angiogenesis);GO:0043154(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process);GO:0048469(cell maturation);GO:0048018(receptor agonist activity);GO:0005125(cytokine activity);GO:0031334(positive regulation of protein complex assembly);GO:0030141(secretory granule);GO:0035148(tube formation);GO:0051781(positive regulation of cell division);GO:0046982(protein heterodimerization activity);GO:0001569(branching involved in blood vessel morphogenesis);GO:0002042(cell migration involved in sprouting angiogenesis);GO:0035767(endothelial cell chemotaxis);GO:0035924(cellular response to vascular endothelial growth factor stimulus);GO:0038190(VEGF-activated neuropilin signaling pathway);GO:0048842(positive regulation of axon extension involved in axon guidance);GO:0048844(artery morphogenesis);GO:0050918(positive chemotaxis);GO:0071679(commissural neuron axon guidance);GO:0090259(regulation of retinal ganglion cell axon guidance);GO:0097475(motor neuron migration);GO:1902336(positive regulation of retinal ganglion cell axon guidance);GO:0043406(positive regulation of MAP kinase activity);GO:0071542(dopaminergic neuron differentiation);GO:0032147(activation of protein kinase activity);GO:0003007(heart morphogenesis);GO:0048739(cardiac muscle fiber development);GO:0042056(chemoattractant activity);GO:0071456(cellular response to hypoxia);GO:0001822(kidney development);GO:0005172(vascular endothelial growth factor receptor binding);GO:0050930(induction of positive chemotaxis);GO:0030324(lung development);GO:0043184(vascular endothelial growth factor receptor 2 binding);GO:0002092(positive regulation of receptor internalization);GO:1900086(positive regulation of peptidyl-tyrosine autophosphorylation);GO:0001570(vasculogenesis);GO:0031954(positive regulation of protein autophosphorylation);GO:0002053(positive regulation of mesenchymal cell proliferation);GO:1900745(positive regulation of p38MAPK cascade);GO:0005161(platelet-derived growth factor receptor binding);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0050679(positive regulation of epithelial cell proliferation);GO:0030949(positive regulation of vascular endothelial growth factor receptor signaling pathway);GO:0051894(positive regulation of focal adhesion assembly);GO:0038033(positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway);GO:0042462(eye photoreceptor cell development);GO:0001968(fibronectin binding);GO:0030823(regulation of cGMP metabolic process);GO:0050927(positive regulation of positive chemotaxis);GO:0038091(positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway);GO:0001701(in utero embryonic development);GO:0030224(monocyte differentiation);GO:0030225(macrophage differentiation);GO:0048593(camera-type eye morphogenesis);GO:0002052(positive regulation of neuroblast proliferation);GO:0051272(positive regulation of cellular component movement);GO:0043183(vascular endothelial growth factor receptor 1 binding);GO:0050840(extracellular matrix binding);GO:0001541(ovarian follicle development);GO:0002687(positive regulation of leukocyte migration);GO:0003169(coronary vein morphogenesis);GO:0007498(mesoderm development);GO:0007595(lactation);GO:0030855(epithelial cell differentiation);GO:0031077(post-embryonic camera-type eye development);GO:0032793(positive regulation of CREB transcription factor activity);GO:0036303(lymph vessel morphogenesis);GO:0040007(growth);GO:0043129(surfactant homeostasis);GO:0048754(branching morphogenesis of an epithelial tube);GO:0060319(primitive erythrocyte differentiation);GO:0060749(mammary gland alveolus development);GO:0060754(positive regulation of mast cell chemotaxis);GO:0060948(cardiac vascular smooth muscle cell development);GO:0060982(coronary artery morphogenesis);GO:0061419(positive regulation of transcription from RNA polymerase II promoter in response to hypoxia);GO:0090037(positive regulation of protein kinase C signaling);GO:0090050(positive regulation of cell migration involved in sprouting angiogenesis);GO:0090190(positive regulation of branching involved in ureteric bud morphogenesis);GO:1901727(positive regulation of histone deacetylase activity);GO:1903572(positive regulation of protein kinase D signaling);GO:1903572(positive regulation of protein kinase D signaling)","04014(Ras signaling pathway);04015(Rap1 signaling pathway);04010(MAPK signaling pathway);04370(VEGF signaling pathway);04066(HIF-1 signaling pathway);04151(PI3K-Akt signaling pathway);04060(Cytokine-cytokine receptor interaction);04510(Focal adhesion);04926(Relaxin signaling pathway);05200(Pathways in cancer);05206(MicroRNAs in cancer);05205(Proteoglycans in cancer);05212(Pancreatic cancer);05211(Renal cell carcinoma);05219(Bladder cancer);05323(Rheumatoid arthritis);05418(Fluid shear stress and atherosclerosis);04933(AGE-RAGE signaling pathway in diabetic complications);05167(Kaposi's sarcoma-associated herpesvirus infection);05165(Human papillomavirus infection);01521(EGFR tyrosine kinase inhibitor resistance);01521(EGFR tyrosine kinase inhibitor resistance)","K05448","NA","vascular endothelial growth factor A [Source:HGNC Symbol;Acc:HGNC:12680]",{"v":0.284438063474465,"d":"0.28"},{"v":0.108027779918232,"d":"0.11"},{"v":2.63300850660599,"d":"2.63"},{"v":1.39671218238605,"d":"1.40"},{"v":0.101477851435608,"d":"0.10"},{"v":0.64730192128267,"d":"0.65"},"up","no"]
["MSTRG.5719","AC130456.3","ENST00000561762;MSTRG.5719.1","NA","NA","NA","NA",null,{"v":24.1366310387029,"d":"24.14"},{"v":42.4695914539749,"d":"42.47"},{"v":0.568327365825033,"d":"0.57"},{"v":-0.815205909870236,"d":"-0.82"},{"v":0.101593116274346,"d":"0.10"},{"v":0.64730192128267,"d":"0.65"},"down","no"]
["MSTRG.13040","UBR2","ENST00000372899;ENST00000372901;ENST00000372903","GO:0005634(nucleus);GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0016740(transferase activity);GO:0016567(protein ubiquitination);GO:0005515(protein binding);GO:0030163(protein catabolic process);GO:0005737(cytoplasm);GO:0000151(ubiquitin ligase complex);GO:0061630(ubiquitin protein ligase activity);GO:0005829(cytosol);GO:0000209(protein polyubiquitination);GO:0032007(negative regulation of TOR signaling);GO:0006342(chromatin silencing);GO:0004842(ubiquitin-protein transferase activity);GO:0033522(histone H2A ubiquitination);GO:0070728(leucine binding);GO:0071233(cellular response to leucine);GO:0071596(ubiquitin-dependent protein catabolic process via the N-end rule pathway);GO:0006511(ubiquitin-dependent protein catabolic process);GO:0007141(male meiosis I);GO:0007283(spermatogenesis);GO:0000785(chromatin);GO:0000785(chromatin)","NA","NA","NA","ubiquitin protein ligase E3 component n-recognin 2 [Source:HGNC Symbol;Acc:HGNC:21289]",{"v":19.7646839621041,"d":"19.76"},{"v":7.74224966866516,"d":"7.74"},{"v":2.55283474544831,"d":"2.55"},{"v":1.35210014971578,"d":"1.35"},{"v":0.101610104373561,"d":"0.10"},{"v":0.64730192128267,"d":"0.65"},"up","no"]
["MSTRG.10158","MED15","ENST00000263205;ENST00000493216;ENST00000292733;ENST00000428629;ENST00000406969;ENST00000445189;ENST00000414658;ENST00000476767;ENST00000441501;ENST00000489651;ENST00000420849;ENST00000423862;ENST00000476187;ENST00000382974;ENST00000487550;ENST00000436496;ENST00000444094;ENST00000492381;ENST00000486656;ENST00000433831;ENST00000473244;ENST00000478831;ENST00000424287;ENST00000445987;ENST00000457322","GO:0005634(nucleus);GO:0001104(RNA polymerase II transcription cofactor activity);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0016592(mediator complex);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0005515(protein binding);GO:0005654(nucleoplasm);GO:0006367(transcription initiation from RNA polymerase II promoter);GO:0006367(transcription initiation from RNA polymerase II promoter)","NA","NA","NA","mediator complex subunit 15 [Source:HGNC Symbol;Acc:HGNC:14248]",{"v":7.61084156140351,"d":"7.61"},{"v":2.97326353017158,"d":"2.97"},{"v":2.5597601706581,"d":"2.56"},{"v":1.35600864740868,"d":"1.36"},{"v":0.101613078233029,"d":"0.10"},{"v":0.64730192128267,"d":"0.65"},"up","no"]
["MSTRG.1320","ATP2B4","ENST00000357681;ENST00000458092;ENST00000466407;ENST00000484746;ENST00000356729","GO:1901205(negative regulation of adrenergic receptor signaling pathway involved in heart process);GO:0045019(negative regulation of nitric oxide biosynthetic process);GO:1900082(negative regulation of arginine catabolic process);GO:1903243(negative regulation of cardiac muscle hypertrophy in response to stress);GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0016787(hydrolase activity);GO:0005886(plasma membrane);GO:0006811(ion transport);GO:0042995(cell projection);GO:0005515(protein binding);GO:0005388(calcium-transporting ATPase activity);GO:0006816(calcium ion transport);GO:0070588(calcium ion transmembrane transport);GO:0099132(ATP hydrolysis coupled cation transmembrane transport);GO:0019901(protein kinase binding);GO:0030165(PDZ domain binding);GO:0003407(neural retina development);GO:0006874(cellular calcium ion homeostasis);GO:0007283(spermatogenesis);GO:0021766(hippocampus development);GO:0030317(flagellated sperm motility);GO:0070885(negative regulation of calcineurin-NFAT signaling cascade);GO:1901660(calcium ion export);GO:0016323(basolateral plasma membrane);GO:0030315(T-tubule);GO:0036126(sperm flagellum);GO:0042383(sarcolemma);GO:0043005(neuron projection);GO:0097228(sperm principal piece);GO:0005516(calmodulin binding);GO:0034220(ion transmembrane transport);GO:0005887(integral component of plasma membrane);GO:0033138(positive regulation of peptidyl-serine phosphorylation);GO:0017080(sodium channel regulator activity);GO:1903779(regulation of cardiac conduction);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0097110(scaffold protein binding);GO:0030018(Z disc);GO:0005901(caveola);GO:0043231(intracellular membrane-bounded organelle);GO:0043234(protein complex);GO:0010751(negative regulation of nitric oxide mediated signal transduction);GO:0050998(nitric-oxide synthase binding);GO:1902083(negative regulation of peptidyl-cysteine S-nitrosylation);GO:0071872(cellular response to epinephrine stimulus);GO:0030346(protein phosphatase 2B binding);GO:0036487(nitric-oxide synthase inhibitor activity);GO:0051001(negative regulation of nitric-oxide synthase activity);GO:0051599(response to hydrostatic pressure);GO:0097553(calcium ion transmembrane import into cytosol);GO:0098703(calcium ion import across plasma membrane);GO:0098736(negative regulation of the force of heart contraction);GO:1902305(regulation of sodium ion transmembrane transport);GO:1902806(regulation of cell cycle G1/S phase transition);GO:1903249(negative regulation of citrulline biosynthetic process);GO:2000481(positive regulation of cAMP-dependent protein kinase activity);GO:2000481(positive regulation of cAMP-dependent protein kinase activity)","04020(Calcium signaling pathway);04024(cAMP signaling pathway);04022(cGMP - PKG signaling pathway);04925(Aldosterone synthesis and secretion);04261(Adrenergic signaling in cardiomyocytes);04970(Salivary secretion);04972(Pancreatic secretion);04972(Pancreatic secretion)","K05850","EC:3.6.3.8","ATPase plasma membrane Ca2+ transporting 4 [Source:HGNC Symbol;Acc:HGNC:817]",{"v":18.4646157732744,"d":"18.46"},{"v":7.23330770311696,"d":"7.23"},{"v":2.55272090323458,"d":"2.55"},{"v":1.3520358121163,"d":"1.35"},{"v":0.101647354137492,"d":"0.10"},{"v":0.64730192128267,"d":"0.65"},"up","no"]
["ENSG00000125885","MCM8","ENST00000610722;ENST00000265187;ENST00000378896;ENST00000378883;ENST00000378886","GO:0005634(nucleus);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0016787(hydrolase activity);GO:0003677(DNA binding);GO:0004386(helicase activity);GO:0005515(protein binding);GO:0006270(DNA replication initiation);GO:0006281(DNA repair);GO:0006974(cellular response to DNA damage stimulus);GO:0007049(cell cycle);GO:0006260(DNA replication);GO:0005654(nucleoplasm);GO:0000082(G1/S transition of mitotic cell cycle);GO:0007292(female gamete generation);GO:0097362(MCM8-MCM9 complex);GO:0048232(male gamete generation);GO:0000724(double-strand break repair via homologous recombination);GO:0000724(double-strand break repair via homologous recombination)","NA","NA","NA","minichromosome maintenance 8 homologous recombination repair factor [Source:HGNC Symbol;Acc:HGNC:16147]",{"v":0.646217667403459,"d":"0.65"},{"v":0.249213735925107,"d":"0.25"},{"v":2.59302588199897,"d":"2.59"},{"v":1.3746366063629,"d":"1.37"},{"v":0.10169292386962,"d":"0.10"},{"v":0.64730192128267,"d":"0.65"},"up","no"]
["ENSG00000224650","IGHV3-74","ENST00000424969","GO:0016020(membrane);GO:0005886(plasma membrane);GO:0005576(extracellular region);GO:0002376(immune system process);GO:0003823(antigen binding);GO:0002250(adaptive immune response);GO:0034987(immunoglobulin receptor binding);GO:0006910(phagocytosis, recognition);GO:0006911(phagocytosis, engulfment);GO:0006958(complement activation, classical pathway);GO:0042742(defense response to bacterium);GO:0045087(innate immune response);GO:0050853(B cell receptor signaling pathway);GO:0050871(positive regulation of B cell activation);GO:0009897(external side of plasma membrane);GO:0042571(immunoglobulin complex, circulating);GO:0072562(blood microparticle)","NA","NA","NA","immunoglobulin heavy variable 3-74 [Source:HGNC Symbol;Acc:HGNC:5624]",{"v":1.255225,"d":"1.26"},{"v":2.333022,"d":"2.33"},{"v":0.538025359383666,"d":"0.54"},{"v":-0.894253920256356,"d":"-0.89"},{"v":0.101724447286737,"d":"0.10"},{"v":0.64730192128267,"d":"0.65"},"down","no"]
["MSTRG.6969","HOXB2","ENST00000330070;ENST00000504772;MSTRG.6969.1;ENST00000571287","GO:0005634(nucleus);GO:0016607(nuclear speck);GO:0005829(cytosol);GO:0006355(regulation of transcription, DNA-templated);GO:0006366(transcription from RNA polymerase II promoter);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0043565(sequence-specific DNA binding);GO:0007275(multicellular organism development);GO:0005654(nucleoplasm);GO:0001228(transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0008015(blood circulation);GO:0002011(morphogenesis of an epithelial sheet);GO:0009952(anterior/posterior pattern specification);GO:0009953(dorsal/ventral pattern formation);GO:0021569(rhombomere 3 development);GO:0021570(rhombomere 4 development);GO:0021612(facial nerve structural organization);GO:0048704(embryonic skeletal system morphogenesis);GO:0048705(skeletal system morphogenesis);GO:0048857(neural nucleus development);GO:0048857(neural nucleus development)","NA","NA","NA","homeobox B2 [Source:HGNC Symbol;Acc:HGNC:5113]",{"v":1.95261619227609,"d":"1.95"},{"v":3.46697871035333,"d":"3.47"},{"v":0.563203975393634,"d":"0.56"},{"v":-0.8282705775662,"d":"-0.83"},{"v":0.101830436170776,"d":"0.10"},{"v":0.647483025535217,"d":"0.65"},"down","no"]
["MSTRG.15511","RPL10","ENST00000344746;ENST00000436473;ENST00000467168;ENST00000491035;ENST00000451365;ENST00000449494;ENST00000369817;MSTRG.15511.3;ENST00000479366;MSTRG.15511.6;ENST00000492572;ENST00000485196;ENST00000406022;ENST00000458500;MSTRG.15511.2;ENST00000482732;ENST00000618723;ENST00000489200;ENST00000424325","GO:0003723(RNA binding);GO:0016020(membrane);GO:0006412(translation);GO:0030529(intracellular ribonucleoprotein complex);GO:0005622(intracellular);GO:0003735(structural constituent of ribosome);GO:0005840(ribosome);GO:0005515(protein binding);GO:0000027(ribosomal large subunit assembly);GO:0005829(cytosol);GO:0005783(endoplasmic reticulum);GO:0043234(protein complex);GO:0006413(translational initiation);GO:0006364(rRNA processing);GO:0005634(nucleus);GO:0000184(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay);GO:0019083(viral transcription);GO:0006614(SRP-dependent cotranslational protein targeting to membrane);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0022625(cytosolic large ribosomal subunit);GO:0005790(smooth endoplasmic reticulum);GO:0043066(negative regulation of apoptotic process);GO:0043066(negative regulation of apoptotic process)","03010(Ribosome);03010(Ribosome)","K02866","NA","ribosomal protein L10 [Source:HGNC Symbol;Acc:HGNC:10298]",{"v":124.493171405596,"d":"124.49"},{"v":218.48454324228,"d":"218.48"},{"v":0.569803106243283,"d":"0.57"},{"v":-0.811464608449247,"d":"-0.81"},{"v":0.101944914110521,"d":"0.10"},{"v":0.647483025535217,"d":"0.65"},"down","no"]
["MSTRG.15080","BRD3","ENST00000303407;ENST00000433041;ENST00000494743;ENST00000371834","GO:0005634(nucleus);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0016569(covalent chromatin modification);GO:0005515(protein binding);GO:0003682(chromatin binding);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0070577(lysine-acetylated histone binding);GO:0070577(lysine-acetylated histone binding)","NA","NA","NA","bromodomain containing 3 [Source:HGNC Symbol;Acc:HGNC:1104]",{"v":5.54842962347295,"d":"5.55"},{"v":2.17015485994764,"d":"2.17"},{"v":2.55669755457305,"d":"2.56"},{"v":1.35428150656123,"d":"1.35"},{"v":0.101950740219643,"d":"0.10"},{"v":0.647483025535217,"d":"0.65"},"up","no"]
["ENSG00000176438","SYNE3","ENST00000334258;ENST00000557275;ENST00000554873;ENST00000555759;ENST00000553340","GO:0005634(nucleus);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0031965(nuclear membrane);GO:0005783(endoplasmic reticulum);GO:0008092(cytoskeletal protein binding);GO:0090286(cytoskeletal anchoring at nuclear membrane);GO:0005640(nuclear outer membrane);GO:0005515(protein binding);GO:0051015(actin filament binding);GO:0007010(cytoskeleton organization);GO:0008360(regulation of cell shape);GO:0005635(nuclear envelope);GO:0090150(establishment of protein localization to membrane);GO:0005791(rough endoplasmic reticulum);GO:0034993(LINC complex);GO:0034993(LINC complex)","NA","NA","NA","spectrin repeat containing nuclear envelope family member 3 [Source:HGNC Symbol;Acc:HGNC:19861]",{"v":2.14104573293327,"d":"2.14"},{"v":0.836876948249284,"d":"0.84"},{"v":2.55837580114049,"d":"2.56"},{"v":1.35522819800385,"d":"1.36"},{"v":0.101975928158436,"d":"0.10"},{"v":0.647483025535217,"d":"0.65"},"up","no"]
["ENSG00000186951","PPARA","ENST00000481567;ENST00000420804;ENST00000262735;ENST00000493286;ENST00000440343;ENST00000415785;ENST00000407236;ENST00000624793;ENST00000460086","GO:0005634(nucleus);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0004879(RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding);GO:0030522(intracellular receptor signaling pathway);GO:0008270(zinc ion binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0043565(sequence-specific DNA binding);GO:0050728(negative regulation of inflammatory response);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0046872(metal ion binding);GO:0005654(nucleoplasm);GO:0006366(transcription from RNA polymerase II promoter);GO:0006351(transcription, DNA-templated);GO:0005515(protein binding);GO:0003707(steroid hormone receptor activity);GO:0043401(steroid hormone mediated signaling pathway);GO:0048511(rhythmic process);GO:0045893(positive regulation of transcription, DNA-templated);GO:0008289(lipid binding);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:0001078(transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0001190(transcriptional activator activity, RNA polymerase II transcription factor binding);GO:0001223(transcription coactivator binding);GO:0004872(receptor activity);GO:0019902(phosphatase binding);GO:0019904(protein domain specific binding);GO:0032403(protein complex binding);GO:0051525(NFAT protein binding);GO:0097371(MDM2/MDM4 family protein binding);GO:0001666(response to hypoxia);GO:0006631(fatty acid metabolic process);GO:0007507(heart development);GO:0008544(epidermis development);GO:0010468(regulation of gene expression);GO:0019217(regulation of fatty acid metabolic process);GO:0032091(negative regulation of protein binding);GO:0032099(negative regulation of appetite);GO:0032868(response to insulin);GO:0032922(circadian regulation of gene expression);GO:0035095(behavioral response to nicotine);GO:0042060(wound healing);GO:0042157(lipoprotein metabolic process);GO:0042752(regulation of circadian rhythm);GO:0045722(positive regulation of gluconeogenesis);GO:0045776(negative regulation of blood pressure);GO:0046321(positive regulation of fatty acid oxidation);GO:0070166(enamel mineralization);GO:1901215(negative regulation of neuron death);GO:2000678(negative regulation of transcription regulatory region DNA binding);GO:0008134(transcription factor binding);GO:0006367(transcription initiation from RNA polymerase II promoter);GO:0008144(drug binding);GO:0006629(lipid metabolic process);GO:0001077(transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:1902894(negative regulation of pri-miRNA transcription from RNA polymerase II promoter);GO:0001103(RNA polymerase II repressing transcription factor binding);GO:0019216(regulation of lipid metabolic process);GO:0010745(negative regulation of macrophage derived foam cell differentiation);GO:0010887(negative regulation of cholesterol storage);GO:0015908(fatty acid transport);GO:1903038(negative regulation of leukocyte cell-cell adhesion);GO:0010871(negative regulation of receptor biosynthetic process);GO:0010891(negative regulation of sequestering of triglyceride);GO:0045820(negative regulation of glycolytic process);GO:0072369(regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoter);GO:0032000(positive regulation of fatty acid beta-oxidation);GO:0031624(ubiquitin conjugating enzyme binding);GO:0072363(regulation of glycolytic process by positive regulation of transcription from RNA polymerase II promoter);GO:0072366(regulation of cellular ketone metabolic process by positive regulation of transcription from RNA polymerase II promoter);GO:0072366(regulation of cellular ketone metabolic process by positive regulation of transcription from RNA polymerase II promoter)","04024(cAMP signaling pathway);04922(Glucagon signaling pathway);04920(Adipocytokine signaling pathway);03320(PPAR signaling pathway);04932(Non-alcoholic fatty liver disease (NAFLD));04931(Insulin resistance);05160(Hepatitis C);05160(Hepatitis C)","K07294","NA","peroxisome proliferator activated receptor alpha [Source:HGNC Symbol;Acc:HGNC:9232]",{"v":1.27324707406006,"d":"1.27"},{"v":0.495188994175051,"d":"0.50"},{"v":2.57123459737064,"d":"2.57"},{"v":1.36246124650867,"d":"1.36"},{"v":0.102067149083661,"d":"0.10"},{"v":0.647599881169429,"d":"0.65"},"up","no"]
["MSTRG.8849","POLE4","ENST00000483063;ENST00000485527;ENST00000465242;ENST00000459636;ENST00000233699;ENST00000473023","GO:0005634(nucleus);GO:0016740(transferase activity);GO:0003677(DNA binding);GO:0046982(protein heterodimerization activity);GO:0005515(protein binding);GO:0016779(nucleotidyltransferase activity);GO:0003887(DNA-directed DNA polymerase activity);GO:0071897(DNA biosynthetic process);GO:0005654(nucleoplasm);GO:0000082(G1/S transition of mitotic cell cycle);GO:0043966(histone H3 acetylation);GO:0005671(Ada2/Gcn5/Ada3 transcription activator complex);GO:0006270(DNA replication initiation);GO:0032201(telomere maintenance via semi-conservative replication);GO:0008622(epsilon DNA polymerase complex);GO:0008622(epsilon DNA polymerase complex)","00230(Purine metabolism);00240(Pyrimidine metabolism);03030(DNA replication);03410(Base excision repair);03420(Nucleotide excision repair);05166(HTLV-I infection);05166(HTLV-I infection)","K03506","EC:2.7.7.7","DNA polymerase epsilon 4, accessory subunit [Source:HGNC Symbol;Acc:HGNC:18755]",{"v":3.21625122361692,"d":"3.22"},{"v":5.69165951836355,"d":"5.69"},{"v":0.565081451769913,"d":"0.57"},{"v":-0.823469259934632,"d":"-0.82"},{"v":0.102114884515619,"d":"0.10"},{"v":0.647599881169429,"d":"0.65"},"down","no"]
["MSTRG.11337","TNIK","ENST00000357327;ENST00000470834;ENST00000475336;ENST00000436636;ENST00000341852;ENST00000284483;ENST00000488470;ENST00000484051;ENST00000460047;ENST00000465393;ENST00000459881;ENST00000496492;ENST00000464785;ENST00000487846;ENST00000468757","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0016055(Wnt signaling pathway);GO:0007399(nervous system development);GO:0000185(activation of MAPKKK activity);GO:0005768(endosome);GO:0070062(extracellular exosome);GO:0001934(positive regulation of protein phosphorylation);GO:0007010(cytoskeleton organization);GO:0055037(recycling endosome);GO:0016324(apical plasma membrane);GO:0042981(regulation of apoptotic process);GO:0046777(protein autophosphorylation);GO:0008349(MAP kinase kinase kinase kinase activity);GO:0007346(regulation of mitotic cell cycle);GO:0035556(intracellular signal transduction);GO:0030033(microvillus assembly);GO:0031532(actin cytoskeleton reorganization);GO:0048814(regulation of dendrite morphogenesis);GO:0072659(protein localization to plasma membrane);GO:0007256(activation of JNKK activity);GO:0007256(activation of JNKK activity)","NA","NA","NA","TRAF2 and NCK interacting kinase [Source:HGNC Symbol;Acc:HGNC:30765]",{"v":3.61454615640033,"d":"3.61"},{"v":1.4096924720169,"d":"1.41"},{"v":2.56406714808434,"d":"2.56"},{"v":1.35843404391445,"d":"1.36"},{"v":0.102161627684698,"d":"0.10"},{"v":0.647599881169429,"d":"0.65"},"up","no"]
["ENSG00000105662","CRTC1","ENST00000338797;ENST00000321949","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0005886(plasma membrane);GO:0051289(protein homotetramerization);GO:0005515(protein binding);GO:0016604(nuclear body);GO:0048511(rhythmic process);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0016032(viral process);GO:0032793(positive regulation of CREB transcription factor activity);GO:0008140(cAMP response element binding protein binding);GO:0043153(entrainment of circadian clock by photoperiod);GO:0007613(memory);GO:0097009(energy homeostasis);GO:1900006(positive regulation of dendrite development);GO:1900273(positive regulation of long-term synaptic potentiation);GO:1902631(negative regulation of membrane hyperpolarization);GO:0030425(dendrite);GO:0043025(neuronal cell body);GO:0045202(synapse);GO:0045202(synapse)","05166(HTLV-I infection);05166(HTLV-I infection)","K15309","NA","CREB regulated transcription coactivator 1 [Source:HGNC Symbol;Acc:HGNC:16062]",{"v":1.49715389849246,"d":"1.50"},{"v":0.582438906676238,"d":"0.58"},{"v":2.57049088124308,"d":"2.57"},{"v":1.36204389417005,"d":"1.36"},{"v":0.102388968273294,"d":"0.10"},{"v":0.648686900467957,"d":"0.65"},"up","no"]
["MSTRG.9558","STK35","ENST00000381482","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0016604(nuclear body);GO:0005730(nucleolus)","NA","NA","NA","serine/threonine kinase 35 [Source:HGNC Symbol;Acc:HGNC:16254]",{"v":4.47371286392629,"d":"4.47"},{"v":1.75168983274274,"d":"1.75"},{"v":2.55394121739092,"d":"2.55"},{"v":1.35272531973345,"d":"1.35"},{"v":0.102479582911168,"d":"0.10"},{"v":0.648906977288658,"d":"0.65"},"up","no"]
["MSTRG.2054","ZNF511;AL360181.5;PRAP1","ENST00000361518;ENST00000359035;ENST00000368554;ENST00000482153;ENST00000463816;ENST00000463201","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0005576(extracellular region)","04140(Autophagy - animal)","K21250","NA","zinc finger protein 511 [Source:HGNC Symbol;Acc:HGNC:28445];proline rich acidic protein 1 [Source:HGNC Symbol;Acc:HGNC:23304]",{"v":1.47889314841849,"d":"1.48"},{"v":2.61760326736956,"d":"2.62"},{"v":0.564979867978479,"d":"0.56"},{"v":-0.823728634235778,"d":"-0.82"},{"v":0.102790057039914,"d":"0.10"},{"v":0.649774841669611,"d":"0.65"},"down","no"]
["MSTRG.4581","SLIRP;C14orf178","ENST00000557342;ENST00000238688;ENST00000557431;ENST00000557623;ENST00000553981;ENST00000554074;ENST00000556047;ENST00000555890;ENST00000556956;ENST00000556831;ENST00000613856","GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0005634(nucleus);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0005739(mitochondrion);GO:0005515(protein binding);GO:0000961(negative regulation of mitochondrial RNA catabolic process);GO:0007286(spermatid development);GO:0007338(single fertilization);GO:0030317(flagellated sperm motility);GO:0070584(mitochondrion morphogenesis);GO:0001669(acrosomal vesicle);GO:0005737(cytoplasm);GO:0030529(intracellular ribonucleoprotein complex);GO:0036126(sperm flagellum);GO:0048471(perinuclear region of cytoplasm);GO:0048471(perinuclear region of cytoplasm)","NA","NA","NA","SRA stem-loop interacting RNA binding protein [Source:HGNC Symbol;Acc:HGNC:20495];chromosome 14 open reading frame 178 [Source:HGNC Symbol;Acc:HGNC:26385]",{"v":1.65740285849673,"d":"1.66"},{"v":2.93411805882353,"d":"2.93"},{"v":0.564872587015563,"d":"0.56"},{"v":-0.824002605784827,"d":"-0.82"},{"v":0.102792517594117,"d":"0.10"},{"v":0.649774841669611,"d":"0.65"},"down","no"]
["MSTRG.5840","ZNF48","ENST00000524644;ENST00000320159;ENST00000613509;ENST00000528032","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0003677(DNA binding)","NA","NA","NA","zinc finger protein 48 [Source:HGNC Symbol;Acc:HGNC:13114]",{"v":0.606911480769231,"d":"0.61"},{"v":1.09423224439103,"d":"1.09"},{"v":0.554645948225547,"d":"0.55"},{"v":-0.850360957176983,"d":"-0.85"},{"v":0.102812521404022,"d":"0.10"},{"v":0.649774841669611,"d":"0.65"},"down","no"]
["MSTRG.9041","BCL2L11","ENST00000393256;ENST00000622612;ENST00000622509;ENST00000405953;ENST00000615946;ENST00000619294;ENST00000452231;ENST00000357757;ENST00000308659;ENST00000621302;ENST00000620862;ENST00000337565;ENST00000433098;ENST00000393252;ENST00000361493;ENST00000431217;ENST00000432179","GO:0016020(membrane);GO:0005739(mitochondrion);GO:0005515(protein binding);GO:0006915(apoptotic process);GO:0005829(cytosol);GO:0008017(microtubule binding);GO:0012505(endomembrane system);GO:0043065(positive regulation of apoptotic process);GO:0032464(positive regulation of protein homooligomerization);GO:0090200(positive regulation of release of cytochrome c from mitochondria);GO:0005741(mitochondrial outer membrane);GO:0034976(response to endoplasmic reticulum stress);GO:1900740(positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway);GO:0001844(protein insertion into mitochondrial membrane involved in apoptotic signaling pathway);GO:0008630(intrinsic apoptotic signaling pathway in response to DNA damage);GO:1902237(positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway);GO:1903896(positive regulation of IRE1-mediated unfolded protein response);GO:2000271(positive regulation of fibroblast apoptotic process);GO:2001244(positive regulation of intrinsic apoptotic signaling pathway);GO:0046982(protein heterodimerization activity);GO:0070840(dynein complex binding);GO:0001701(in utero embryonic development);GO:0001776(leukocyte homeostasis);GO:0001782(B cell homeostasis);GO:0001783(B cell apoptotic process);GO:0001822(kidney development);GO:0002260(lymphocyte homeostasis);GO:0002262(myeloid cell homeostasis);GO:0007160(cell-matrix adhesion);GO:0007283(spermatogenesis);GO:0007420(brain development);GO:0008584(male gonad development);GO:0009791(post-embryonic development);GO:0010942(positive regulation of cell death);GO:0030879(mammary gland development);GO:0035148(tube formation);GO:0042475(odontogenesis of dentin-containing tooth);GO:0042981(regulation of apoptotic process);GO:0043029(T cell homeostasis);GO:0043280(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process);GO:0043525(positive regulation of neuron apoptotic process);GO:0043583(ear development);GO:0045787(positive regulation of cell cycle);GO:0046620(regulation of organ growth);GO:0048066(developmental pigmentation);GO:0048070(regulation of developmental pigmentation);GO:0048536(spleen development);GO:0048538(thymus development);GO:0048563(post-embryonic animal organ morphogenesis);GO:0060139(positive regulation of apoptotic process by virus);GO:0060154(cellular process regulating host cell cycle in response to virus);GO:0070242(thymocyte apoptotic process);GO:0097192(extrinsic apoptotic signaling pathway in absence of ligand);GO:1902110(positive regulation of mitochondrial membrane permeability involved in apoptotic process);GO:1902263(apoptotic process involved in embryonic digit morphogenesis);GO:0005737(cytoplasm);GO:0005868(cytoplasmic dynein complex);GO:0019898(extrinsic component of membrane);GO:0043231(intracellular membrane-bounded organelle);GO:0097136(Bcl-2 family protein complex);GO:0097136(Bcl-2 family protein complex)","04068(FoxO signaling pathway);04151(PI3K-Akt signaling pathway);04210(Apoptosis);04215(Apoptosis - multiple species);05200(Pathways in cancer);05206(MicroRNAs in cancer);05210(Colorectal cancer);04932(Non-alcoholic fatty liver disease (NAFLD));01521(EGFR tyrosine kinase inhibitor resistance);01521(EGFR tyrosine kinase inhibitor resistance)","K16341","NA","BCL2 like 11 [Source:HGNC Symbol;Acc:HGNC:994]",{"v":8.0102282753079,"d":"8.01"},{"v":3.13156599339141,"d":"3.13"},{"v":2.55789860159805,"d":"2.56"},{"v":1.35495907505962,"d":"1.35"},{"v":0.102880359037186,"d":"0.10"},{"v":0.649774841669611,"d":"0.65"},"up","no"]
["MSTRG.1546","UPF2","ENST00000357604;ENST00000397053;ENST00000460569","GO:0005634(nucleus);GO:0003723(RNA binding);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005515(protein binding);GO:0048471(perinuclear region of cytoplasm);GO:0000932(P-body);GO:0035145(exon-exon junction complex);GO:0000184(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay);GO:0042162(telomeric DNA binding);GO:0005844(polysome);GO:0006406(mRNA export from nucleus);GO:0001889(liver development);GO:0031100(animal organ regeneration);GO:0031100(animal organ regeneration)","03013(RNA transport);03015(mRNA surveillance pathway);03015(mRNA surveillance pathway)","K14327","NA","UPF2, regulator of nonsense mediated mRNA decay [Source:HGNC Symbol;Acc:HGNC:17854]",{"v":9.21849685336946,"d":"9.22"},{"v":3.61566287876735,"d":"3.62"},{"v":2.54960076823098,"d":"2.55"},{"v":1.35027135893301,"d":"1.35"},{"v":0.102926138428616,"d":"0.10"},{"v":0.649774841669611,"d":"0.65"},"up","no"]
["MSTRG.8795","ANXA4","MSTRG.8795.2;MSTRG.8795.4;MSTRG.8795.3;MSTRG.8795.1","NA","NA","NA","NA",null,{"v":9.28117569077491,"d":"9.28"},{"v":16.3262679874539,"d":"16.33"},{"v":0.568481155516198,"d":"0.57"},{"v":-0.814815568626356,"d":"-0.81"},{"v":0.102952355866019,"d":"0.10"},{"v":0.649774841669611,"d":"0.65"},"down","no"]
["MSTRG.4160","DAD1","ENST00000250498;ENST00000535847;ENST00000543337;ENST00000489532;ENST00000538631","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0006915(apoptotic process);GO:0006486(protein glycosylation);GO:0004579(dolichyl-diphosphooligosaccharide-protein glycotransferase activity);GO:0008250(oligosaccharyltransferase complex);GO:0070062(extracellular exosome);GO:0043066(negative regulation of apoptotic process);GO:0006487(protein N-linked glycosylation);GO:0018279(protein N-linked glycosylation via asparagine);GO:0004576(oligosaccharyl transferase activity);GO:0001824(blastocyst development);GO:0007584(response to nutrient);GO:0042493(response to drug);GO:0016740(transferase activity);GO:0016740(transferase activity)","00510(N-Glycan biosynthesis);04141(Protein processing in endoplasmic reticulum);04141(Protein processing in endoplasmic reticulum)","K12668","NA","defender against cell death 1 [Source:HGNC Symbol;Acc:HGNC:2664]",{"v":46.1557893527228,"d":"46.16"},{"v":80.9236095668317,"d":"80.92"},{"v":0.570362464054504,"d":"0.57"},{"v":-0.810049054733021,"d":"-0.81"},{"v":0.103044768637654,"d":"0.10"},{"v":0.650004833345506,"d":"0.65"},"down","no"]
["MSTRG.13814","PPP1R35","ENST00000292330;ENST00000487452;ENST00000470295;ENST00000476185;ENST00000491407","GO:0004864(protein phosphatase inhibitor activity);GO:0019902(phosphatase binding);GO:0010923(negative regulation of phosphatase activity);GO:0010923(negative regulation of phosphatase activity)","NA","NA","NA","protein phosphatase 1 regulatory subunit 35 [Source:HGNC Symbol;Acc:HGNC:28320]",{"v":6.42438979022746,"d":"6.42"},{"v":11.33738389385,"d":"11.34"},{"v":0.566655398668505,"d":"0.57"},{"v":-0.81945644220529,"d":"-0.82"},{"v":0.103214055599947,"d":"0.10"},{"v":0.650493391929046,"d":"0.65"},"down","no"]
["ENSG00000125740","FOSB","ENST00000353609;ENST00000592811;ENST00000587358;ENST00000590335;ENST00000586615;ENST00000591858;ENST00000586113;ENST00000592436","GO:0005634(nucleus);GO:0043231(intracellular membrane-bounded organelle);GO:0005654(nucleoplasm);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0008134(transcription factor binding);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:0001077(transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0003690(double-stranded DNA binding);GO:0043565(sequence-specific DNA binding);GO:0006366(transcription from RNA polymerase II promoter);GO:0007565(female pregnancy);GO:0009612(response to mechanical stimulus);GO:0032570(response to progesterone);GO:0032870(cellular response to hormone stimulus);GO:0042493(response to drug);GO:0043278(response to morphine);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0051412(response to corticosterone);GO:0051591(response to cAMP);GO:0071277(cellular response to calcium ion);GO:0071277(cellular response to calcium ion)","04657(IL-17 signaling pathway);04380(Osteoclast differentiation);05030(Cocaine addiction);05031(Amphetamine addiction);05034(Alcoholism);05034(Alcoholism)","K09029","NA","FosB proto-oncogene, AP-1 transcription factor subunit [Source:HGNC Symbol;Acc:HGNC:3797]",{"v":0.550157127678732,"d":"0.55"},{"v":0.209460019809112,"d":"0.21"},{"v":2.62654958297106,"d":"2.63"},{"v":1.39316881937984,"d":"1.39"},{"v":0.103234247939829,"d":"0.10"},{"v":0.650493391929046,"d":"0.65"},"up","no"]
["ENSG00000148848","ADAM12","ENST00000368679;ENST00000494661;ENST00000368676;ENST00000448723;ENST00000482291","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0046872(metal ion binding);GO:0005654(nucleoplasm);GO:0016787(hydrolase activity);GO:0007155(cell adhesion);GO:0005886(plasma membrane);GO:0008233(peptidase activity);GO:0006508(proteolysis);GO:0005576(extracellular region);GO:0004222(metalloendopeptidase activity);GO:0008237(metallopeptidase activity);GO:0017124(SH3 domain binding);GO:0030198(extracellular matrix organization);GO:0007520(myoblast fusion);GO:0005615(extracellular space);GO:0005615(extracellular space)","NA","NA","NA","ADAM metallopeptidase domain 12 [Source:HGNC Symbol;Acc:HGNC:190]",{"v":0.397582453853955,"d":"0.40"},{"v":0.152060357910751,"d":"0.15"},{"v":2.6146357888182,"d":"2.61"},{"v":1.38660999723297,"d":"1.39"},{"v":0.103338177539447,"d":"0.10"},{"v":0.650795149547507,"d":"0.65"},"up","no"]
["MSTRG.1289","SHISA4","ENST00000362011;ENST00000464117","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016021(integral component of membrane)","NA","NA","NA","shisa family member 4 [Source:HGNC Symbol;Acc:HGNC:27139]",{"v":6.3977724742268,"d":"6.40"},{"v":2.49181880469645,"d":"2.49"},{"v":2.5675111136366,"d":"2.57"},{"v":1.36037052135504,"d":"1.36"},{"v":0.103486571531651,"d":"0.10"},{"v":0.650862965280192,"d":"0.65"},"up","no"]
["MSTRG.15449","RBMX2","ENST00000305536;ENST00000639890;ENST00000487274;ENST00000469953;ENST00000370947","GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0005515(protein binding);GO:0000398(mRNA splicing, via spliceosome);GO:0071011(precatalytic spliceosome);GO:0071013(catalytic step 2 spliceosome);GO:0005686(U2 snRNP);GO:0006406(mRNA export from nucleus);GO:0000384(first spliceosomal transesterification activity);GO:0070274(RES complex);GO:0070274(RES complex)","NA","NA","NA","RNA binding motif protein, X-linked 2 [Source:HGNC Symbol;Acc:HGNC:24282]",{"v":1.26231738016861,"d":"1.26"},{"v":2.2540036234444,"d":"2.25"},{"v":0.560033429866289,"d":"0.56"},{"v":-0.836415146890651,"d":"-0.84"},{"v":0.103637884956655,"d":"0.10"},{"v":0.650862965280192,"d":"0.65"},"down","no"]
["ENSG00000197928","ZNF677","ENST00000594681;ENST00000598513;ENST00000601413;ENST00000333952;ENST00000595293;ENST00000601828;ENST00000594517;ENST00000593539;ENST00000599328;ENST00000599012;ENST00000598806","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0005622(intracellular);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding)","NA","NA","NA","zinc finger protein 677 [Source:HGNC Symbol;Acc:HGNC:28730]",{"v":0.30531542821994,"d":"0.31"},{"v":0.113575947689345,"d":"0.11"},{"v":2.68820498029252,"d":"2.69"},{"v":1.4266431503103,"d":"1.43"},{"v":0.103735737950836,"d":"0.10"},{"v":0.650862965280192,"d":"0.65"},"up","no"]
["ENSG00000090104","RGS1","ENST00000583155;ENST00000498352;ENST00000367459;ENST00000469578","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0043547(positive regulation of GTPase activity);GO:0007165(signal transduction);GO:0005096(GTPase activator activity);GO:0008277(regulation of G-protein coupled receptor protein signaling pathway);GO:0007186(G-protein coupled receptor signaling pathway);GO:0031234(extrinsic component of cytoplasmic side of plasma membrane);GO:0006955(immune response);GO:0009968(negative regulation of signal transduction);GO:0005516(calmodulin binding);GO:0001965(G-protein alpha-subunit binding);GO:0007193(adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway);GO:0061737(leukotriene signaling pathway);GO:0061737(leukotriene signaling pathway)","NA","NA","NA","regulator of G protein signaling 1 [Source:HGNC Symbol;Acc:HGNC:9991]",{"v":0.192085525868351,"d":"0.19"},{"v":0.359153985183386,"d":"0.36"},{"v":0.534827772467208,"d":"0.53"},{"v":-0.902853711429929,"d":"-0.90"},{"v":0.103750276101795,"d":"0.10"},{"v":0.650862965280192,"d":"0.65"},"down","no"]
["MSTRG.7647","JSRP1","ENST00000300961;ENST00000593238","GO:0016020(membrane);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0003009(skeletal muscle contraction);GO:0016529(sarcoplasmic reticulum);GO:0033017(sarcoplasmic reticulum membrane);GO:0060314(regulation of ryanodine-sensitive calcium-release channel activity);GO:0060314(regulation of ryanodine-sensitive calcium-release channel activity)","NA","NA","NA","junctional sarcoplasmic reticulum protein 1 [Source:HGNC Symbol;Acc:HGNC:24963]",{"v":0.408427063076923,"d":"0.41"},{"v":0.761363663076923,"d":"0.76"},{"v":0.536441496861479,"d":"0.54"},{"v":-0.89850725249832,"d":"-0.90"},{"v":0.103750276101795,"d":"0.10"},{"v":0.650862965280192,"d":"0.65"},"down","no"]
["ENSG00000182108","DEXI","ENST00000331808;ENST00000469379","NA","NA","NA","NA","Dexi homolog [Source:HGNC Symbol;Acc:HGNC:13267]",{"v":1.30508041056911,"d":"1.31"},{"v":2.34263242276423,"d":"2.34"},{"v":0.557099952125292,"d":"0.56"},{"v":-0.843991902871703,"d":"-0.84"},{"v":0.103820741370962,"d":"0.10"},{"v":0.650862965280192,"d":"0.65"},"down","no"]
["MSTRG.514","RPS8;SNORD38A","ENST00000470475;ENST00000396651;ENST00000372209;ENST00000474582;ENST00000485390;ENST00000484599;ENST00000497035;ENST00000464658;ENST00000365161","GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0006412(translation);GO:0005783(endoplasmic reticulum);GO:0005829(cytosol);GO:0030529(intracellular ribonucleoprotein complex);GO:0005622(intracellular);GO:0003735(structural constituent of ribosome);GO:0005840(ribosome);GO:0022627(cytosolic small ribosomal subunit);GO:0005925(focal adhesion);GO:0000462(maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA));GO:0005654(nucleoplasm);GO:0070062(extracellular exosome);GO:0005515(protein binding);GO:0006413(translational initiation);GO:0006364(rRNA processing);GO:0000184(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay);GO:0019083(viral transcription);GO:0006614(SRP-dependent cotranslational protein targeting to membrane);GO:0006614(SRP-dependent cotranslational protein targeting to membrane)","03010(Ribosome);03010(Ribosome)","K02995","NA","ribosomal protein S8 [Source:HGNC Symbol;Acc:HGNC:10441];small nucleolar RNA, C/D box 38A [Source:HGNC Symbol;Acc:HGNC:30355]",{"v":121.966212011352,"d":"121.97"},{"v":213.140677267286,"d":"213.14"},{"v":0.572233388647827,"d":"0.57"},{"v":-0.805324416465492,"d":"-0.81"},{"v":0.103895961508156,"d":"0.10"},{"v":0.650862965280192,"d":"0.65"},"down","no"]
["MSTRG.7973","COLGALT1","ENST00000252599;ENST00000593832;ENST00000601354;ENST00000597075;ENST00000600474;ENST00000597147","GO:0016020(membrane);GO:0016740(transferase activity);GO:0016757(transferase activity, transferring glycosyl groups);GO:0005783(endoplasmic reticulum);GO:0005788(endoplasmic reticulum lumen);GO:0050211(procollagen galactosyltransferase activity);GO:0050211(procollagen galactosyltransferase activity)","00310(Lysine degradation);00514(Other types of O-glycan biosynthesis);00514(Other types of O-glycan biosynthesis)","K11703","EC:2.4.1.50","collagen beta(1-O)galactosyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:26182]",{"v":12.3270159136735,"d":"12.33"},{"v":4.84629252734694,"d":"4.85"},{"v":2.543597160946,"d":"2.54"},{"v":1.34687020367085,"d":"1.35"},{"v":0.103909782026708,"d":"0.10"},{"v":0.650862965280192,"d":"0.65"},"up","no"]
["ENSG00000262222","AC133065.2","ENST00000573379","NA","NA","NA","NA",null,{"v":1.361978,"d":"1.36"},{"v":0.514395,"d":"0.51"},{"v":2.64772791337396,"d":"2.65"},{"v":1.40475487509285,"d":"1.40"},{"v":0.103966386649961,"d":"0.10"},{"v":0.650862965280192,"d":"0.65"},"up","no"]
["MSTRG.322","DNAJC8","ENST00000263697;ENST00000489277;ENST00000603289;ENST00000482674;ENST00000470967;ENST00000488868","GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0045171(intercellular bridge);GO:0000398(mRNA splicing, via spliceosome);GO:0000398(mRNA splicing, via spliceosome)","NA","NA","NA","DnaJ heat shock protein family (Hsp40) member C8 [Source:HGNC Symbol;Acc:HGNC:15470]",{"v":14.7483400422438,"d":"14.75"},{"v":25.8013349324792,"d":"25.80"},{"v":0.571611510832268,"d":"0.57"},{"v":-0.806893125875921,"d":"-0.81"},{"v":0.103987955198448,"d":"0.10"},{"v":0.650862965280192,"d":"0.65"},"down","no"]
["MSTRG.7245","RHBDF2","MSTRG.7245.4;ENST00000587640;ENST00000590288;ENST00000589582;ENST00000591860;ENST00000590168;ENST00000590322;ENST00000591255;ENST00000591697;ENST00000585701;ENST00000585989;ENST00000592123;ENST00000591192;ENST00000589526;ENST00000593103;ENST00000591879;ENST00000313080","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0015031(protein transport);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005886(plasma membrane);GO:0006508(proteolysis);GO:0019838(growth factor binding);GO:0050708(regulation of protein secretion);GO:0042058(regulation of epidermal growth factor receptor signaling pathway);GO:0050709(negative regulation of protein secretion);GO:0016787(hydrolase activity);GO:0008233(peptidase activity);GO:0004252(serine-type endopeptidase activity);GO:0004252(serine-type endopeptidase activity)","NA","NA","NA","rhomboid 5 homolog 2 [Source:HGNC Symbol;Acc:HGNC:20788]",{"v":5.28755624985557,"d":"5.29"},{"v":2.07379294974003,"d":"2.07"},{"v":2.54970306969093,"d":"2.55"},{"v":1.35032924519108,"d":"1.35"},{"v":0.104031757347333,"d":"0.10"},{"v":0.650862965280192,"d":"0.65"},"up","no"]
["ENSG00000148737","TCF7L2","ENST00000471569;ENST00000494353;ENST00000543371;ENST00000536810;ENST00000277945;ENST00000542695;ENST00000545257;ENST00000369386;ENST00000637574;ENST00000637416;ENST00000629706;ENST00000355995;ENST00000466338;ENST00000627217;ENST00000480888;ENST00000369389;ENST00000538897;ENST00000346198;ENST00000369395;ENST00000355717","GO:0051897(positive regulation of protein kinase B signaling);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0043433(negative regulation of sequence-specific DNA binding transcription factor activity);GO:0005634(nucleus);GO:0008013(beta-catenin binding);GO:0060070(canonical Wnt signaling pathway);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0016055(Wnt signaling pathway);GO:2001237(negative regulation of extrinsic apoptotic signaling pathway);GO:0005654(nucleoplasm);GO:0019901(protein kinase binding);GO:0090090(negative regulation of canonical Wnt signaling pathway);GO:0070016(armadillo repeat domain binding);GO:0043565(sequence-specific DNA binding);GO:0032024(positive regulation of insulin secretion);GO:0044212(transcription regulatory region DNA binding);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0045892(negative regulation of transcription, DNA-templated);GO:1904837(beta-catenin-TCF complex assembly);GO:0000790(nuclear chromatin);GO:0016605(PML body);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0032092(positive regulation of protein binding);GO:0001103(RNA polymerase II repressing transcription factor binding);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:0007223(Wnt signaling pathway, calcium modulating pathway);GO:0045444(fat cell differentiation);GO:0008134(transcription factor binding);GO:0042593(glucose homeostasis);GO:2000675(negative regulation of type B pancreatic cell apoptotic process);GO:0007050(cell cycle arrest);GO:0046827(positive regulation of protein export from nucleus);GO:0009749(response to glucose);GO:0008283(cell proliferation);GO:0045295(gamma-catenin binding);GO:0032993(protein-DNA complex);GO:0035257(nuclear hormone receptor binding);GO:0010909(positive regulation of heparan sulfate proteoglycan biosynthetic process);GO:0044334(canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition);GO:0048660(regulation of smooth muscle cell proliferation);GO:0070369(beta-catenin-TCF7L2 complex);GO:0001568(blood vessel development);GO:0031016(pancreas development);GO:0048625(myoblast fate commitment);GO:0032350(regulation of hormone metabolic process);GO:0043570(maintenance of DNA repeat elements);GO:0043570(maintenance of DNA repeat elements)","04310(Wnt signaling pathway);04390(Hippo signaling pathway);04520(Adherens junction);04916(Melanogenesis);05200(Pathways in cancer);05210(Colorectal cancer);05225(Hepatocellular carcinoma);05226(Gastric cancer);05216(Thyroid cancer);05221(Acute myeloid leukemia);05217(Basal cell carcinoma);05215(Prostate cancer);05213(Endometrial cancer);05224(Breast cancer);05412(Arrhythmogenic right ventricular cardiomyopathy (ARVC));05165(Human papillomavirus infection);05165(Human papillomavirus infection)","K04491","NA","transcription factor 7 like 2 [Source:HGNC Symbol;Acc:HGNC:11641]",{"v":0.844385101247031,"d":"0.84"},{"v":0.32636023381829,"d":"0.33"},{"v":2.58727937337233,"d":"2.59"},{"v":1.37143584405644,"d":"1.37"},{"v":0.104031869061899,"d":"0.10"},{"v":0.650862965280192,"d":"0.65"},"up","no"]
["ENSG00000225830","ERCC6","ENST00000355832;ENST00000623115;ENST00000374127;ENST00000475116;ENST00000623788;ENST00000465653;ENST00000623073;ENST00000447839;ENST00000479652;ENST00000624341","GO:0005634(nucleus);GO:0005794(Golgi apparatus);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0005829(cytosol);GO:0016787(hydrolase activity);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0004386(helicase activity);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0006281(DNA repair);GO:0006974(cellular response to DNA damage stimulus);GO:0005654(nucleoplasm);GO:0005730(nucleolus);GO:0061098(positive regulation of protein tyrosine kinase activity);GO:0006366(transcription from RNA polymerase II promoter);GO:0003682(chromatin binding);GO:0008022(protein C-terminus binding);GO:0006284(base-excision repair);GO:0045815(positive regulation of gene expression, epigenetic);GO:0047485(protein N-terminus binding);GO:0006979(response to oxidative stress);GO:0009411(response to UV);GO:0032786(positive regulation of DNA-templated transcription, elongation);GO:0008023(transcription elongation factor complex);GO:0032403(protein complex binding);GO:0008094(DNA-dependent ATPase activity);GO:0006283(transcription-coupled nucleotide-excision repair);GO:0030296(protein tyrosine kinase activator activity);GO:0000303(response to superoxide);GO:0006290(pyrimidine dimer repair);GO:0006362(transcription elongation from RNA polymerase I promoter);GO:0007256(activation of JNKK activity);GO:0007257(activation of JUN kinase activity);GO:0008630(intrinsic apoptotic signaling pathway in response to DNA damage);GO:0009636(response to toxic substance);GO:0010165(response to X-ray);GO:0010224(response to UV-B);GO:0010332(response to gamma radiation);GO:0032784(regulation of DNA-templated transcription, elongation);GO:0035264(multicellular organism growth);GO:0045494(photoreceptor cell maintenance);GO:0045494(photoreceptor cell maintenance)","03420(Nucleotide excision repair);03420(Nucleotide excision repair)","K10841","NA","ERCC excision repair 6, chromatin remodeling factor [Source:HGNC Symbol;Acc:HGNC:3438]",{"v":1.21302014674075,"d":"1.21"},{"v":0.474840816036327,"d":"0.47"},{"v":2.55458272704162,"d":"2.55"},{"v":1.353087656411,"d":"1.35"},{"v":0.104167914776413,"d":"0.10"},{"v":0.650862965280192,"d":"0.65"},"up","no"]
["ENSG00000198932","GPRASP1","ENST00000415986;ENST00000466098;ENST00000537097;ENST00000361600","GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005515(protein binding);GO:0008333(endosome to lysosome transport);GO:1990172(G-protein coupled receptor catabolic process);GO:1990172(G-protein coupled receptor catabolic process)","NA","NA","NA","G protein-coupled receptor associated sorting protein 1 [Source:HGNC Symbol;Acc:HGNC:24834]",{"v":1.36377273249211,"d":"1.36"},{"v":0.530513242429022,"d":"0.53"},{"v":2.57066671182024,"d":"2.57"},{"v":1.36214257618755,"d":"1.36"},{"v":0.104187949477287,"d":"0.10"},{"v":0.650862965280192,"d":"0.65"},"up","no"]
["ENSG00000107863","ARHGAP21","ENST00000376410;ENST00000396432;ENST00000486374;ENST00000472150;ENST00000477190;ENST00000638156;ENST00000463892;ENST00000636842;ENST00000482792;ENST00000636789;ENST00000416305;ENST00000476067;ENST00000418033;ENST00000483114;ENST00000476499","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0007165(signal transduction);GO:0005794(Golgi apparatus);GO:0005886(plasma membrane);GO:0030054(cell junction);GO:0015629(actin cytoskeleton);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0000139(Golgi membrane);GO:0030659(cytoplasmic vesicle membrane);GO:0031410(cytoplasmic vesicle);GO:0005096(GTPase activator activity);GO:0043547(positive regulation of GTPase activity);GO:0005829(cytosol);GO:0051056(regulation of small GTPase mediated signal transduction);GO:0007030(Golgi organization);GO:0051683(establishment of Golgi localization);GO:0072384(organelle transport along microtubule);GO:0051684(maintenance of Golgi location);GO:0051684(maintenance of Golgi location)","NA","NA","NA","Rho GTPase activating protein 21 [Source:HGNC Symbol;Acc:HGNC:23725]",{"v":2.65512368940294,"d":"2.66"},{"v":1.0448183137972,"d":"1.04"},{"v":2.54123004386608,"d":"2.54"},{"v":1.345526980713,"d":"1.35"},{"v":0.104189636825616,"d":"0.10"},{"v":0.650862965280192,"d":"0.65"},"up","no"]
["ENSG00000151929","BAG3","ENST00000369085;ENST00000450186","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0050790(regulation of catalytic activity);GO:0005515(protein binding);GO:0006915(apoptotic process);GO:0051087(chaperone binding);GO:0045296(cadherin binding);GO:0006457(protein folding);GO:0043066(negative regulation of apoptotic process);GO:0042993(positive regulation of transcription factor import into nucleus);GO:1900034(regulation of cellular response to heat);GO:0034605(cellular response to heat);GO:0046827(positive regulation of protein export from nucleus);GO:0000774(adenyl-nucleotide exchange factor activity);GO:0032403(protein complex binding);GO:0007420(brain development);GO:0008625(extrinsic apoptotic signaling pathway via death domain receptors);GO:0010664(negative regulation of striated muscle cell apoptotic process);GO:0021510(spinal cord development);GO:0050821(protein stabilization);GO:0071260(cellular response to mechanical stimulus);GO:0097192(extrinsic apoptotic signaling pathway in absence of ligand);GO:0097201(negative regulation of transcription from RNA polymerase II promoter in response to stress);GO:0030018(Z disc);GO:0043005(neuron projection);GO:0043005(neuron projection)","NA","NA","NA","BCL2 associated athanogene 3 [Source:HGNC Symbol;Acc:HGNC:939]",{"v":2.96265478012377,"d":"2.96"},{"v":1.14780418711321,"d":"1.15"},{"v":2.5811500022273,"d":"2.58"},{"v":1.36801398536103,"d":"1.37"},{"v":0.104363660168787,"d":"0.10"},{"v":0.651599562118348,"d":"0.65"},"up","no"]
["ENSG00000153130","SCOC","ENST00000608372;ENST00000614192;ENST00000394201;ENST00000506597;ENST00000510586;ENST00000502535","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005794(Golgi apparatus);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0005515(protein binding);GO:0000139(Golgi membrane);GO:0016239(positive regulation of macroautophagy);GO:0005802(trans-Golgi network);GO:0005768(endosome);GO:0061635(regulation of protein complex stability);GO:0061635(regulation of protein complex stability)","NA","NA","NA","short coiled-coil protein [Source:HGNC Symbol;Acc:HGNC:20335]",{"v":0.544354624880839,"d":"0.54"},{"v":0.968824571655545,"d":"0.97"},{"v":0.561871200222178,"d":"0.56"},{"v":-0.831688640770455,"d":"-0.83"},{"v":0.104627779466578,"d":"0.10"},{"v":0.652559099541525,"d":"0.65"},"down","no"]
["MSTRG.11477","RPL35A","ENST00000448864;ENST00000429437;ENST00000439255;ENST00000442341;ENST00000464167;ENST00000496582;ENST00000474640;MSTRG.11477.1;ENST00000485439;ENST00000329092","GO:0003723(RNA binding);GO:0016020(membrane);GO:0006412(translation);GO:0030529(intracellular ribonucleoprotein complex);GO:0005622(intracellular);GO:0003735(structural constituent of ribosome);GO:0005840(ribosome);GO:0000049(tRNA binding);GO:0006364(rRNA processing);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0031012(extracellular matrix);GO:0042273(ribosomal large subunit biogenesis);GO:0005515(protein binding);GO:0002181(cytoplasmic translation);GO:0006413(translational initiation);GO:0000184(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay);GO:0019083(viral transcription);GO:0006614(SRP-dependent cotranslational protein targeting to membrane);GO:0022625(cytosolic large ribosomal subunit);GO:0022625(cytosolic large ribosomal subunit)","03010(Ribosome);03010(Ribosome)","K02917","NA","ribosomal protein L35a [Source:HGNC Symbol;Acc:HGNC:10345]",{"v":107.147591319495,"d":"107.15"},{"v":186.943100966456,"d":"186.94"},{"v":0.573156167655104,"d":"0.57"},{"v":-0.8029998117433,"d":"-0.80"},{"v":0.104638557534874,"d":"0.10"},{"v":0.652559099541525,"d":"0.65"},"down","no"]
["MSTRG.13843","SH2B2","ENST00000536178;ENST00000444095;ENST00000617975","GO:0005829(cytosol);GO:0035556(intracellular signal transduction);GO:0007165(signal transduction);GO:0004871(signal transducer activity);GO:0035591(signaling adaptor activity);GO:0009967(positive regulation of signal transduction);GO:0005068(transmembrane receptor protein tyrosine kinase adaptor activity);GO:0005070(SH3/SH2 adaptor activity);GO:0042802(identical protein binding);GO:0001922(B-1 B cell homeostasis);GO:0007399(nervous system development);GO:0008286(insulin receptor signaling pathway);GO:0019221(cytokine-mediated signaling pathway);GO:0019222(regulation of metabolic process);GO:0030036(actin cytoskeleton organization);GO:0046578(regulation of Ras protein signal transduction);GO:0050776(regulation of immune response);GO:0050851(antigen receptor-mediated signaling pathway);GO:0050873(brown fat cell differentiation);GO:0001725(stress fiber);GO:0001726(ruffle);GO:0005884(actin filament);GO:0005884(actin filament)","04910(Insulin signaling pathway);04722(Neurotrophin signaling pathway);04722(Neurotrophin signaling pathway)","K07193","NA","SH2B adaptor protein 2 [Source:HGNC Symbol;Acc:HGNC:17381]",{"v":7.87953238087248,"d":"7.88"},{"v":3.09227464219799,"d":"3.09"},{"v":2.54813472042435,"d":"2.55"},{"v":1.34944155520414,"d":"1.35"},{"v":0.104740064045484,"d":"0.10"},{"v":0.652559099541525,"d":"0.65"},"up","no"]
["ENSG00000230383","AC009245.1","ENST00000456481","NA","NA","NA","NA",null,{"v":1.933739,"d":"1.93"},{"v":3.472171,"d":"3.47"},{"v":0.556925047758305,"d":"0.56"},{"v":-0.844444915443203,"d":"-0.84"},{"v":0.104742113282132,"d":"0.10"},{"v":0.652559099541525,"d":"0.65"},"down","no"]
["ENSG00000161981","SNRNP25","ENST00000293861;ENST00000383018;ENST00000466183;ENST00000397876;ENST00000481947","GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0045171(intercellular bridge);GO:0006397(mRNA processing);GO:0008380(RNA splicing);GO:0005634(nucleus);GO:0005515(protein binding);GO:0005681(spliceosomal complex);GO:0000398(mRNA splicing, via spliceosome);GO:0005689(U12-type spliceosomal complex);GO:0005689(U12-type spliceosomal complex)","NA","NA","NA","small nuclear ribonucleoprotein U11/U12 subunit 25 [Source:HGNC Symbol;Acc:HGNC:14161]",{"v":1.23096441666667,"d":"1.23"},{"v":2.16420382026144,"d":"2.16"},{"v":0.568783958859276,"d":"0.57"},{"v":-0.814047316991406,"d":"-0.81"},{"v":0.104832013908137,"d":"0.10"},{"v":0.652768995986698,"d":"0.65"},"down","no"]
["MSTRG.11121","GSK3B","ENST00000316626;ENST00000264235;ENST00000473886;ENST00000474830","GO:0005737(cytoplasm);GO:0005739(mitochondrion);GO:0005634(nucleus);GO:0016020(membrane);GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0007623(circadian rhythm);GO:0048511(rhythmic process);GO:0007275(multicellular organism development);GO:0016055(Wnt signaling pathway);GO:0007399(nervous system development);GO:0030154(cell differentiation);GO:0005975(carbohydrate metabolic process);GO:0005813(centrosome);GO:0098794(postsynapse);GO:0005829(cytosol);GO:0019901(protein kinase binding);GO:0090090(negative regulation of canonical Wnt signaling pathway);GO:0043161(proteasome-mediated ubiquitin-dependent protein catabolic process);GO:0043547(positive regulation of GTPase activity);GO:0032092(positive regulation of protein binding);GO:0046777(protein autophosphorylation);GO:0001954(positive regulation of cell-matrix adhesion);GO:0060070(canonical Wnt signaling pathway);GO:0009968(negative regulation of signal transduction);GO:0032091(negative regulation of protein binding);GO:1904886(beta-catenin destruction complex disassembly);GO:0008013(beta-catenin binding);GO:0031625(ubiquitin protein ligase binding);GO:0045732(positive regulation of protein catabolic process);GO:1904885(beta-catenin destruction complex assembly);GO:0030877(beta-catenin destruction complex);GO:0018105(peptidyl-serine phosphorylation);GO:0051059(NF-kappaB binding);GO:1900034(regulation of cellular response to heat);GO:0035556(intracellular signal transduction);GO:0010822(positive regulation of mitochondrion organization);GO:0032436(positive regulation of proteasomal ubiquitin-dependent protein catabolic process);GO:0032886(regulation of microtubule-based process);GO:1990909(Wnt signalosome);GO:0005977(glycogen metabolic process);GO:0018107(peptidyl-threonine phosphorylation);GO:0001837(epithelial to mesenchymal transition);GO:0031334(positive regulation of protein complex assembly);GO:0036016(cellular response to interleukin-3);GO:0006983(ER overload response);GO:1901216(positive regulation of neuron death);GO:0002020(protease binding);GO:0043066(negative regulation of apoptotic process);GO:0034236(protein kinase A catalytic subunit binding);GO:0099565(chemical synaptic transmission, postsynaptic);GO:0050321(tau-protein kinase activity);GO:0001085(RNA polymerase II transcription factor binding);GO:0007212(dopamine receptor signaling pathway);GO:0021766(hippocampus development);GO:0045719(negative regulation of glycogen biosynthetic process);GO:0097192(extrinsic apoptotic signaling pathway in absence of ligand);GO:1901030(positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway);GO:2000077(negative regulation of type B pancreatic cell development);GO:2000466(negative regulation of glycogen (starch) synthase activity);GO:0002039(p53 binding);GO:0031333(negative regulation of protein complex assembly);GO:0046827(positive regulation of protein export from nucleus);GO:0051534(negative regulation of NFAT protein import into nucleus);GO:0071109(superior temporal gyrus development);GO:1900181(negative regulation of protein localization to nucleus);GO:1904339(negative regulation of dopaminergic neuron differentiation);GO:1904339(negative regulation of dopaminergic neuron differentiation)","04012(ErbB signaling pathway);04310(Wnt signaling pathway);04340(Hedgehog signaling pathway);04390(Hippo signaling pathway);04151(PI3K-Akt signaling pathway);04150(mTOR signaling pathway);04110(Cell cycle);04510(Focal adhesion);04550(Signaling pathways regulating pluripotency of stem cells);04660(T cell receptor signaling pathway);04657(IL-17 signaling pathway);04662(B cell receptor signaling pathway);04062(Chemokine signaling pathway);04910(Insulin signaling pathway);04917(Prolactin signaling pathway);04919(Thyroid hormone signaling pathway);04916(Melanogenesis);04728(Dopaminergic synapse);04722(Neurotrophin signaling pathway);04360(Axon guidance);05200(Pathways in cancer);05210(Colorectal cancer);05225(Hepatocellular carcinoma);05226(Gastric cancer);05217(Basal cell carcinoma);05215(Prostate cancer);05213(Endometrial cancer);05224(Breast cancer);05010(Alzheimer's disease);04932(Non-alcoholic fatty liver disease (NAFLD));04931(Insulin resistance);05166(HTLV-I infection);05162(Measles);05164(Influenza A);05160(Hepatitis C);05167(Kaposi's sarcoma-associated herpesvirus infection);05169(Epstein-Barr virus infection);05165(Human papillomavirus infection);01521(EGFR tyrosine kinase inhibitor resistance);01521(EGFR tyrosine kinase inhibitor resistance)","K03083","EC:2.7.11.26","glycogen synthase kinase 3 beta [Source:HGNC Symbol;Acc:HGNC:4617]",{"v":8.08738462090932,"d":"8.09"},{"v":3.18550290057457,"d":"3.19"},{"v":2.5388093727526,"d":"2.54"},{"v":1.34415207387117,"d":"1.34"},{"v":0.104966903933058,"d":"0.10"},{"v":0.653044545019157,"d":"0.65"},"up","no"]
["ENSG00000233621","LINC01137","ENST00000424989","NA","NA","NA","NA","long intergenic non-protein coding RNA 1137 [Source:HGNC Symbol;Acc:HGNC:49453]",{"v":0.810559,"d":"0.81"},{"v":1.476659,"d":"1.48"},{"v":0.548914136574524,"d":"0.55"},{"v":-0.86534760034928,"d":"-0.87"},{"v":0.10498873379409,"d":"0.10"},{"v":0.653044545019157,"d":"0.65"},"down","no"]
["MSTRG.12926","NELFE;MIR1236","ENST00000375429;ENST00000481121;ENST00000436289;ENST00000408340;ENST00000492185;ENST00000454913;ENST00000444811;ENST00000441998;ENST00000426722;ENST00000491139;ENST00000494956;ENST00000488426;ENST00000492539;ENST00000375425","GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0016604(nuclear body);GO:0032021(NELF complex);GO:0003682(chromatin binding);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0034244(negative regulation of transcription elongation from RNA polymerase II promoter);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0051571(positive regulation of histone H3-K4 methylation);GO:0070374(positive regulation of ERK1 and ERK2 cascade);GO:0008150(biological_process);GO:0006366(transcription from RNA polymerase II promoter);GO:0006368(transcription elongation from RNA polymerase II promoter);GO:0050434(positive regulation of viral transcription);GO:1900364(negative regulation of mRNA polyadenylation);GO:1900364(negative regulation of mRNA polyadenylation)","NA","NA","NA","negative elongation factor complex member E [Source:HGNC Symbol;Acc:HGNC:13974];microRNA 1236 [Source:HGNC Symbol;Acc:HGNC:33925]",{"v":9.1462437447591,"d":"9.15"},{"v":15.9856323232806,"d":"15.99"},{"v":0.572154016794132,"d":"0.57"},{"v":-0.805524539919057,"d":"-0.81"},{"v":0.105181003824288,"d":"0.11"},{"v":0.65312294264877,"d":"0.65"},"down","no"]
["MSTRG.495","KDM4A","ENST00000372396;ENST00000485249;ENST00000463151;ENST00000472265;ENST00000481296","GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0005829(cytosol);GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0016569(covalent chromatin modification);GO:0001650(fibrillar center);GO:0008270(zinc ion binding);GO:0005515(protein binding);GO:0051213(dioxygenase activity);GO:0005654(nucleoplasm);GO:0016032(viral process);GO:0031625(ubiquitin protein ligase binding);GO:0010507(negative regulation of autophagy);GO:0032454(histone demethylase activity (H3-K9 specific));GO:0033169(histone H3-K9 demethylation);GO:0045892(negative regulation of transcription, DNA-templated);GO:0032452(histone demethylase activity);GO:0035064(methylated histone binding);GO:0010629(negative regulation of gene expression);GO:0051864(histone demethylase activity (H3-K36 specific));GO:0010628(positive regulation of gene expression);GO:0014898(cardiac muscle hypertrophy in response to stress);GO:0016577(histone demethylation);GO:0031667(response to nutrient levels);GO:0045666(positive regulation of neuron differentiation);GO:0048712(negative regulation of astrocyte differentiation);GO:0060548(negative regulation of cell death);GO:0070544(histone H3-K36 demethylation);GO:1900113(negative regulation of histone H3-K9 trimethylation);GO:0005721(pericentric heterochromatin);GO:0005737(cytoplasm);GO:0005737(cytoplasm)","NA","NA","NA","lysine demethylase 4A [Source:HGNC Symbol;Acc:HGNC:22978]",{"v":6.61836500270688,"d":"6.62"},{"v":2.60132295591647,"d":"2.60"},{"v":2.54423042231416,"d":"2.54"},{"v":1.34722933653265,"d":"1.35"},{"v":0.105181424808751,"d":"0.11"},{"v":0.65312294264877,"d":"0.65"},"up","no"]
["MSTRG.11221","ATP1B3","ENST00000286371;ENST00000475483;ENST00000465172;ENST00000487199;ENST00000486782;ENST00000484727;ENST00000482635","GO:0005886(plasma membrane);GO:0006813(potassium ion transport);GO:0006814(sodium ion transport);GO:0005890(sodium:potassium-exchanging ATPase complex);GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0006811(ion transport);GO:0042470(melanosome);GO:0050900(leukocyte migration);GO:0010248(establishment or maintenance of transmembrane electrochemical gradient);GO:0090662(ATP hydrolysis coupled transmembrane transport);GO:0070062(extracellular exosome);GO:0034220(ion transmembrane transport);GO:1903278(positive regulation of sodium ion export from cell);GO:1903779(regulation of cardiac conduction);GO:0051117(ATPase binding);GO:0050821(protein stabilization);GO:0010107(potassium ion import);GO:0005391(sodium:potassium-exchanging ATPase activity);GO:0006883(cellular sodium ion homeostasis);GO:0030007(cellular potassium ion homeostasis);GO:0036376(sodium ion export from cell);GO:0086009(membrane repolarization);GO:0001671(ATPase activator activity);GO:0032781(positive regulation of ATPase activity);GO:0072659(protein localization to plasma membrane);GO:1901018(positive regulation of potassium ion transmembrane transporter activity);GO:1903288(positive regulation of potassium ion import);GO:0030001(metal ion transport);GO:0005737(cytoplasm);GO:0005901(caveola);GO:0005901(caveola)","04024(cAMP signaling pathway);04022(cGMP - PKG signaling pathway);04911(Insulin secretion);04918(Thyroid hormone synthesis);04919(Thyroid hormone signaling pathway);04925(Aldosterone synthesis and secretion);04260(Cardiac muscle contraction);04261(Adrenergic signaling in cardiomyocytes);04970(Salivary secretion);04971(Gastric acid secretion);04972(Pancreatic secretion);04976(Bile secretion);04973(Carbohydrate digestion and absorption);04974(Protein digestion and absorption);04978(Mineral absorption);04960(Aldosterone-regulated sodium reabsorption);04961(Endocrine and other factor-regulated calcium reabsorption);04964(Proximal tubule bicarbonate reclamation);04964(Proximal tubule bicarbonate reclamation)","K01540","NA","ATPase Na+/K+ transporting subunit beta 3 [Source:HGNC Symbol;Acc:HGNC:806]",{"v":2.68495867647059,"d":"2.68"},{"v":4.71902042647059,"d":"4.72"},{"v":0.568965258427309,"d":"0.57"},{"v":-0.813587532030085,"d":"-0.81"},{"v":0.105242472406121,"d":"0.11"},{"v":0.65312294264877,"d":"0.65"},"down","no"]
["ENSG00000124313","IQSEC2","ENST00000639543;ENST00000639796;ENST00000638630;ENST00000396435;ENST00000639161;ENST00000375365;ENST00000638869;ENST00000639642;ENST00000638521;ENST00000640442;ENST00000640694;ENST00000485377;ENST00000638583","GO:0043547(positive regulation of GTPase activity);GO:0005086(ARF guanyl-nucleotide exchange factor activity);GO:0032012(regulation of ARF protein signal transduction);GO:0005737(cytoplasm);GO:0030036(actin cytoskeleton organization);GO:0030036(actin cytoskeleton organization)","04144(Endocytosis);04144(Endocytosis)","K12495","NA","IQ motif and Sec7 domain 2 [Source:HGNC Symbol;Acc:HGNC:29059]",{"v":0.300774201252578,"d":"0.30"},{"v":0.11441212044604,"d":"0.11"},{"v":2.62886659280501,"d":"2.63"},{"v":1.39444093131234,"d":"1.39"},{"v":0.105271323129678,"d":"0.11"},{"v":0.65312294264877,"d":"0.65"},"up","no"]
["MSTRG.8128","GMFG","ENST00000595636;ENST00000597595;ENST00000595207;ENST00000601387;ENST00000598034;ENST00000253054;ENST00000602185;ENST00000601731;ENST00000594700;ENST00000598218;ENST00000600322;ENST00000596583","GO:0003779(actin binding);GO:0005622(intracellular);GO:2000249(regulation of actin cytoskeleton reorganization);GO:0071933(Arp2/3 complex binding);GO:0034316(negative regulation of Arp2/3 complex-mediated actin nucleation);GO:0008083(growth factor activity);GO:0043085(positive regulation of catalytic activity);GO:0005576(extracellular region);GO:0006469(negative regulation of protein kinase activity);GO:0043312(neutrophil degranulation);GO:0006468(protein phosphorylation);GO:0034774(secretory granule lumen);GO:1904813(ficolin-1-rich granule lumen);GO:0004860(protein kinase inhibitor activity);GO:0008047(enzyme activator activity);GO:0071846(actin filament debranching);GO:0071846(actin filament debranching)","NA","NA","NA","glia maturation factor gamma [Source:HGNC Symbol;Acc:HGNC:4374]",{"v":77.059978395302,"d":"77.06"},{"v":134.319808448993,"d":"134.32"},{"v":0.573705243367474,"d":"0.57"},{"v":-0.801618391355065,"d":"-0.80"},{"v":0.105282541000473,"d":"0.11"},{"v":0.65312294264877,"d":"0.65"},"down","no"]
["MSTRG.1930","SUFU","ENST00000369902;ENST00000369899;ENST00000423559;ENST00000471000","GO:0043433(negative regulation of sequence-specific DNA binding transcription factor activity);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0006355(regulation of transcription, DNA-templated);GO:0008134(transcription factor binding);GO:0005515(protein binding);GO:0007275(multicellular organism development);GO:0097542(ciliary tip);GO:0003714(transcription corepressor activity);GO:0005829(cytosol);GO:0019901(protein kinase binding);GO:0004871(signal transducer activity);GO:0007165(signal transduction);GO:0001501(skeletal system development);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0006508(proteolysis);GO:0045668(negative regulation of osteoblast differentiation);GO:0097546(ciliary base);GO:0045879(negative regulation of smoothened signaling pathway);GO:0042994(cytoplasmic sequestering of transcription factor);GO:0008013(beta-catenin binding);GO:0001843(neural tube closure);GO:0001947(heart looping);GO:0003281(ventricular septum development);GO:0007368(determination of left/right symmetry);GO:0021513(spinal cord dorsal/ventral patterning);GO:0021775(smoothened signaling pathway involved in ventral spinal cord interneuron specification);GO:0021776(smoothened signaling pathway involved in spinal cord motor neuron cell fate specification);GO:0035904(aorta development);GO:0042992(negative regulation of transcription factor import into nucleus);GO:0043588(skin development);GO:0060976(coronary vasculature development);GO:1901621(negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning);GO:2000059(negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process);GO:0005929(cilium);GO:0005929(cilium)","04340(Hedgehog signaling pathway);05200(Pathways in cancer);05217(Basal cell carcinoma);05217(Basal cell carcinoma)","K06229","NA","SUFU negative regulator of hedgehog signaling [Source:HGNC Symbol;Acc:HGNC:16466]",{"v":2.73026090910415,"d":"2.73"},{"v":1.07291744486526,"d":"1.07"},{"v":2.54470735112991,"d":"2.54"},{"v":1.34749975164479,"d":"1.35"},{"v":0.105395145742655,"d":"0.11"},{"v":0.653472411911081,"d":"0.65"},"up","no"]
["MSTRG.593","CYB5RL;AL357673.1","ENST00000497820;ENST00000287899;ENST00000534324;ENST00000311841;ENST00000420054;ENST00000528287;ENST00000490863;ENST00000637610;ENST00000493530","GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0005789(endoplasmic reticulum membrane);GO:0015701(bicarbonate transport);GO:0004128(cytochrome-b5 reductase activity, acting on NAD(P)H);GO:0004128(cytochrome-b5 reductase activity, acting on NAD(P)H)","00520(Amino sugar and nucleotide sugar metabolism);00520(Amino sugar and nucleotide sugar metabolism)","K00326","EC:1.6.2.2","cytochrome b5 reductase like [Source:HGNC Symbol;Acc:HGNC:32220]",{"v":0.115071362415117,"d":"0.12"},{"v":0.207518061116032,"d":"0.21"},{"v":0.554512517109418,"d":"0.55"},{"v":-0.85070806792172,"d":"-0.85"},{"v":0.105458183841856,"d":"0.11"},{"v":0.653514348428746,"d":"0.65"},"down","no"]
["ENSG00000180257","ZNF816","ENST00000444460;ENST00000457013;ENST00000391786;ENST00000357666;ENST00000270457;ENST00000438970;ENST00000535506;ENST00000332302","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0005622(intracellular);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016021(integral component of membrane)","NA","NA","NA","zinc finger protein 816 [Source:HGNC Symbol;Acc:HGNC:26995]",{"v":2.03984381450151,"d":"2.04"},{"v":0.786939118731118,"d":"0.79"},{"v":2.59212404866924,"d":"2.59"},{"v":1.37413476147779,"d":"1.37"},{"v":0.105624871957659,"d":"0.11"},{"v":0.65414846067506,"d":"0.65"},"up","no"]
["ENSG00000181991","MRPS11","ENST00000325844;ENST00000560708;ENST00000559557;ENST00000561262;ENST00000560850;ENST00000557974;ENST00000559125;ENST00000558406;ENST00000353598;ENST00000559323;ENST00000558548","GO:0003723(RNA binding);GO:0005739(mitochondrion);GO:0030529(intracellular ribonucleoprotein complex);GO:0003735(structural constituent of ribosome);GO:0006412(translation);GO:0005840(ribosome);GO:0032543(mitochondrial translation);GO:0000462(maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA));GO:0000028(ribosomal small subunit assembly);GO:0005743(mitochondrial inner membrane);GO:0070125(mitochondrial translational elongation);GO:0070126(mitochondrial translational termination);GO:0005763(mitochondrial small ribosomal subunit);GO:0042769(DNA damage response, detection of DNA damage);GO:0070181(small ribosomal subunit rRNA binding);GO:0048027(mRNA 5'-UTR binding);GO:0048027(mRNA 5'-UTR binding)","03010(Ribosome);03010(Ribosome)","K02948","NA","mitochondrial ribosomal protein S11 [Source:HGNC Symbol;Acc:HGNC:14050]",{"v":1.35604888995556,"d":"1.36"},{"v":2.38729627146667,"d":"2.39"},{"v":0.568027063152263,"d":"0.57"},{"v":-0.815968427577405,"d":"-0.82"},{"v":0.105673169054199,"d":"0.11"},{"v":0.65414846067506,"d":"0.65"},"down","no"]
["MSTRG.10342","RHBDD3","ENST00000216085;ENST00000496342;ENST00000493894;ENST00000406335;ENST00000413137","GO:0005622(intracellular);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0004252(serine-type endopeptidase activity);GO:0000165(MAPK cascade);GO:0001889(liver development);GO:0002673(regulation of acute inflammatory response);GO:0006508(proteolysis);GO:0009410(response to xenobiotic stimulus);GO:0032815(negative regulation of natural killer cell activation);GO:0045732(positive regulation of protein catabolic process);GO:0050708(regulation of protein secretion);GO:0050708(regulation of protein secretion)","NA","NA","NA","rhomboid domain containing 3 [Source:HGNC Symbol;Acc:HGNC:1308]",{"v":0.674664006967485,"d":"0.67"},{"v":1.20041646781685,"d":"1.20"},{"v":0.562024951385805,"d":"0.56"},{"v":-0.83129391383352,"d":"-0.83"},{"v":0.105851618082967,"d":"0.11"},{"v":0.654864003206459,"d":"0.65"},"down","no"]
["MSTRG.2391","TIMM10","ENST00000257245;ENST00000525158","GO:0006810(transport);GO:0016020(membrane);GO:0008565(protein transporter activity);GO:0015031(protein transport);GO:0046872(metal ion binding);GO:0005739(mitochondrion);GO:0005743(mitochondrial inner membrane);GO:0008270(zinc ion binding);GO:0005515(protein binding);GO:0007605(sensory perception of sound);GO:0042803(protein homodimerization activity);GO:0006626(protein targeting to mitochondrion);GO:0005758(mitochondrial intermembrane space);GO:0051087(chaperone binding);GO:0072321(chaperone-mediated protein transport);GO:0005744(mitochondrial inner membrane presequence translocase complex);GO:0005215(transporter activity);GO:0045039(protein import into mitochondrial inner membrane);GO:0042719(mitochondrial intermembrane space protein transporter complex);GO:0042719(mitochondrial intermembrane space protein transporter complex)","NA","NA","NA","translocase of inner mitochondrial membrane 10 [Source:HGNC Symbol;Acc:HGNC:11814]",{"v":4.15737734877735,"d":"4.16"},{"v":7.31110827541828,"d":"7.31"},{"v":0.568638459746994,"d":"0.57"},{"v":-0.814416416185257,"d":"-0.81"},{"v":0.105901541205695,"d":"0.11"},{"v":0.654864003206459,"d":"0.65"},"down","no"]
["ENSG00000169951","ZNF764","ENST00000395091;ENST00000568333;ENST00000252797","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0005622(intracellular);GO:0005515(protein binding);GO:0005515(protein binding)","NA","NA","NA","zinc finger protein 764 [Source:HGNC Symbol;Acc:HGNC:28200]",{"v":0.660757022165114,"d":"0.66"},{"v":1.17722078413106,"d":"1.18"},{"v":0.561285555838056,"d":"0.56"},{"v":-0.833193161525393,"d":"-0.83"},{"v":0.10599284738495,"d":"0.11"},{"v":0.654958243431841,"d":"0.65"},"down","no"]
["MSTRG.3779","TRIAP1","ENST00000546954;ENST00000302432","GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0043154(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process);GO:0006810(transport);GO:0005737(cytoplasm);GO:0005654(nucleoplasm);GO:0005739(mitochondrion);GO:0006915(apoptotic process);GO:0048471(perinuclear region of cytoplasm);GO:0006869(lipid transport);GO:0005515(protein binding);GO:0005758(mitochondrial intermembrane space);GO:0043234(protein complex);GO:0043066(negative regulation of apoptotic process);GO:0042981(regulation of apoptotic process);GO:1990050(phosphatidic acid transporter activity);GO:0002039(p53 binding);GO:0006977(DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest);GO:0015914(phospholipid transport);GO:0030330(DNA damage response, signal transduction by p53 class mediator);GO:0034644(cellular response to UV);GO:0090201(negative regulation of release of cytochrome c from mitochondria);GO:0097035(regulation of membrane lipid distribution);GO:1902166(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator);GO:2001140(positive regulation of phospholipid transport);GO:2001140(positive regulation of phospholipid transport)","NA","NA","NA","TP53 regulated inhibitor of apoptosis 1 [Source:HGNC Symbol;Acc:HGNC:26937]",{"v":2.86717133425797,"d":"2.87"},{"v":5.04256528294036,"d":"5.04"},{"v":0.568593795693231,"d":"0.57"},{"v":-0.814529737995458,"d":"-0.81"},{"v":0.106039683388517,"d":"0.11"},{"v":0.654958243431841,"d":"0.65"},"down","no"]
["MSTRG.5968","USB1","ENST00000561743;ENST00000219281;ENST00000566082;ENST00000423271;ENST00000624720;ENST00000562534;ENST00000561568;ENST00000569252;ENST00000565151;ENST00000539737;ENST00000563207;ENST00000566292;ENST00000565662","GO:0006397(mRNA processing);GO:0008380(RNA splicing);GO:0005634(nucleus);GO:0016787(hydrolase activity);GO:0090305(nucleic acid phosphodiester bond hydrolysis);GO:0004518(nuclease activity);GO:0034477(U6 snRNA 3'-end processing);GO:0045171(intercellular bridge);GO:0090503(RNA phosphodiester bond hydrolysis, exonucleolytic);GO:0000175(3'-5'-exoribonuclease activity);GO:0000175(3'-5'-exoribonuclease activity)","NA","NA","NA","U6 snRNA biogenesis phosphodiesterase 1 [Source:HGNC Symbol;Acc:HGNC:25792]",{"v":4.63759857797943,"d":"4.64"},{"v":1.82797569739867,"d":"1.83"},{"v":2.53701325711225,"d":"2.54"},{"v":1.34313105819575,"d":"1.34"},{"v":0.106137266494116,"d":"0.11"},{"v":0.654958243431841,"d":"0.65"},"up","no"]
["ENSG00000106012","IQCE","ENST00000402050;ENST00000476665;ENST00000470731;ENST00000490913;ENST00000486730;ENST00000427817;ENST00000497572;ENST00000325979;ENST00000415271;ENST00000623361;ENST00000423196;ENST00000325997","GO:0005515(protein binding);GO:0005929(cilium);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0005739(mitochondrion);GO:0019898(extrinsic component of membrane);GO:0060170(ciliary membrane);GO:0098797(plasma membrane protein complex);GO:0098797(plasma membrane protein complex)","NA","NA","NA","IQ motif containing E [Source:HGNC Symbol;Acc:HGNC:29171]",{"v":2.12506660530303,"d":"2.13"},{"v":0.835036808225108,"d":"0.84"},{"v":2.54487776391548,"d":"2.54"},{"v":1.34759636214454,"d":"1.35"},{"v":0.106142376142145,"d":"0.11"},{"v":0.654958243431841,"d":"0.65"},"up","no"]
["ENSG00000085982","USP40","ENST00000251722;ENST00000427112;ENST00000483519;ENST00000450940;ENST00000450966;ENST00000485943;ENST00000409945;ENST00000430158;ENST00000427947;ENST00000484528;ENST00000483216","GO:0016579(protein deubiquitination);GO:0016787(hydrolase activity);GO:0008233(peptidase activity);GO:0008234(cysteine-type peptidase activity);GO:0006508(proteolysis);GO:0006511(ubiquitin-dependent protein catabolic process);GO:0036459(thiol-dependent ubiquitinyl hydrolase activity);GO:0036459(thiol-dependent ubiquitinyl hydrolase activity)","NA","NA","NA","ubiquitin specific peptidase 40 [Source:HGNC Symbol;Acc:HGNC:20069]",{"v":0.780884048331908,"d":"0.78"},{"v":0.302036282185629,"d":"0.30"},{"v":2.58539816038387,"d":"2.59"},{"v":1.37038647774615,"d":"1.37"},{"v":0.106385317722468,"d":"0.11"},{"v":0.656108706697305,"d":"0.66"},"up","no"]
["ENSG00000136068","FLNB","ENST00000295956;ENST00000477629;ENST00000491408;ENST00000490882;ENST00000358537;ENST00000468939;ENST00000466455;ENST00000419752;ENST00000475487;ENST00000481470;ENST00000429972","GO:0003723(RNA binding);GO:0005737(cytoplasm);GO:0016021(integral component of membrane);GO:0005829(cytosol);GO:0003779(actin binding);GO:0005886(plasma membrane);GO:0030036(actin cytoskeleton organization);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0030154(cell differentiation);GO:0007275(multicellular organism development);GO:0005925(focal adhesion);GO:0042802(identical protein binding);GO:0045296(cadherin binding);GO:0070062(extracellular exosome);GO:0005938(cell cortex);GO:0007517(muscle organ development);GO:0031012(extracellular matrix);GO:0007165(signal transduction);GO:0015629(actin cytoskeleton);GO:0030018(Z disc);GO:0003334(keratinocyte development);GO:0003382(epithelial cell morphogenesis);GO:0007016(cytoskeletal anchoring at plasma membrane);GO:0007519(skeletal muscle tissue development);GO:0001725(stress fiber);GO:0005634(nucleus);GO:0005903(brush border);GO:0043005(neuron projection);GO:0043025(neuronal cell body);GO:0043025(neuronal cell body)","04010(MAPK signaling pathway);04510(Focal adhesion);05205(Proteoglycans in cancer);05132(Salmonella infection);05132(Salmonella infection)","K04437","NA","filamin B [Source:HGNC Symbol;Acc:HGNC:3755]",{"v":3.52098359360665,"d":"3.52"},{"v":1.39273647821101,"d":"1.39"},{"v":2.52810466925474,"d":"2.53"},{"v":1.33805619559124,"d":"1.34"},{"v":0.106592899994387,"d":"0.11"},{"v":0.657039993436741,"d":"0.66"},"up","no"]
["ENSG00000178202","KDELC2","ENST00000434945;ENST00000532730;ENST00000530318;ENST00000323468;ENST00000530529","GO:0005783(endoplasmic reticulum);GO:0005788(endoplasmic reticulum lumen);GO:0003674(molecular_function);GO:0008150(biological_process);GO:0005575(cellular_component);GO:0046527(glucosyltransferase activity);GO:0006664(glycolipid metabolic process);GO:0006664(glycolipid metabolic process)","NA","NA","NA","KDEL motif containing 2 [Source:HGNC Symbol;Acc:HGNC:28496]",{"v":1.8143990082115,"d":"1.81"},{"v":0.712315847786902,"d":"0.71"},{"v":2.54718326687335,"d":"2.55"},{"v":1.34890276357659,"d":"1.35"},{"v":0.106796980966345,"d":"0.11"},{"v":0.657948721465336,"d":"0.66"},"up","no"]
["MSTRG.7482","GALNT1","MSTRG.7482.3;ENST00000269195;ENST00000591081;ENST00000590654;ENST00000586725;ENST00000589189","GO:0048471(perinuclear region of cytoplasm);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0046872(metal ion binding);GO:0016740(transferase activity);GO:0030246(carbohydrate binding);GO:0016757(transferase activity, transferring glycosyl groups);GO:0005794(Golgi apparatus);GO:0005576(extracellular region);GO:0006486(protein glycosylation);GO:0032580(Golgi cisterna membrane);GO:0005789(endoplasmic reticulum membrane);GO:0000139(Golgi membrane);GO:0006493(protein O-linked glycosylation);GO:0016266(O-glycan processing);GO:0030145(manganese ion binding);GO:0004653(polypeptide N-acetylgalactosaminyltransferase activity);GO:0018242(protein O-linked glycosylation via serine);GO:0018243(protein O-linked glycosylation via threonine);GO:0018243(protein O-linked glycosylation via threonine)","00512(Mucin type O-glycan biosynthesis);00512(Mucin type O-glycan biosynthesis)","K00710","EC:2.4.1.41","polypeptide N-acetylgalactosaminyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:4123]",{"v":8.83014861498005,"d":"8.83"},{"v":3.49251823667029,"d":"3.49"},{"v":2.52830422537709,"d":"2.53"},{"v":1.33817007033289,"d":"1.34"},{"v":0.10686386546249,"d":"0.11"},{"v":0.658011701811189,"d":"0.66"},"up","no"]
["MSTRG.6199","CRISPLD2","ENST00000262424;ENST00000569090;ENST00000566151;ENST00000566789;ENST00000567845;ENST00000569262;ENST00000565561;ENST00000566165;ENST00000564567","GO:0005576(extracellular region);GO:0005539(glycosaminoglycan binding);GO:0008201(heparin binding);GO:0030198(extracellular matrix organization);GO:0030324(lung development);GO:0005578(proteinaceous extracellular matrix);GO:0070062(extracellular exosome);GO:0043312(neutrophil degranulation);GO:0034774(secretory granule lumen);GO:1904813(ficolin-1-rich granule lumen);GO:0060325(face morphogenesis);GO:0030133(transport vesicle);GO:0030133(transport vesicle)","NA","NA","NA","cysteine rich secretory protein LCCL domain containing 2 [Source:HGNC Symbol;Acc:HGNC:25248]",{"v":9.2108089745135,"d":"9.21"},{"v":3.64502953358443,"d":"3.65"},{"v":2.52695043747857,"d":"2.53"},{"v":1.33739736815879,"d":"1.34"},{"v":0.106970540909535,"d":"0.11"},{"v":0.658319497393974,"d":"0.66"},"up","no"]
["MSTRG.423","MRPS15","ENST00000373116;ENST00000488606;ENST00000477040","GO:0003723(RNA binding);GO:0006412(translation);GO:0005634(nucleus);GO:0005730(nucleolus);GO:0005739(mitochondrion);GO:0030529(intracellular ribonucleoprotein complex);GO:0005622(intracellular);GO:0003735(structural constituent of ribosome);GO:0005840(ribosome);GO:0032543(mitochondrial translation);GO:0005743(mitochondrial inner membrane);GO:0070125(mitochondrial translational elongation);GO:0070126(mitochondrial translational termination);GO:0005763(mitochondrial small ribosomal subunit);GO:0005761(mitochondrial ribosome);GO:0005761(mitochondrial ribosome)","03010(Ribosome);03010(Ribosome)","K02956","NA","mitochondrial ribosomal protein S15 [Source:HGNC Symbol;Acc:HGNC:14504]",{"v":2.93371999862826,"d":"2.93"},{"v":5.12266655761317,"d":"5.12"},{"v":0.572693921346148,"d":"0.57"},{"v":-0.804163804311222,"d":"-0.80"},{"v":0.107140877231548,"d":"0.11"},{"v":0.659018541996807,"d":"0.66"},"down","no"]
["MSTRG.4477","SPTB;MIR7855","ENST00000553938;ENST00000622027;ENST00000556227;ENST00000389721;ENST00000556626;ENST00000342835","GO:0005737(cytoplasm);GO:0005794(Golgi apparatus);GO:0005829(cytosol);GO:0003779(actin binding);GO:0051693(actin filament capping);GO:0043547(positive regulation of GTPase activity);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0005200(structural constituent of cytoskeleton);GO:0007010(cytoskeleton organization);GO:0008091(spectrin);GO:0051015(actin filament binding);GO:0005938(cell cortex);GO:0000165(MAPK cascade);GO:0043234(protein complex);GO:0015629(actin cytoskeleton);GO:0007411(axon guidance);GO:0006888(ER to Golgi vesicle-mediated transport);GO:0005088(Ras guanyl-nucleotide exchange factor activity);GO:0030506(ankyrin binding);GO:0014731(spectrin-associated cytoskeleton);GO:0031235(intrinsic component of the cytoplasmic side of the plasma membrane);GO:0031235(intrinsic component of the cytoplasmic side of the plasma membrane)","NA","NA","NA","spectrin beta, erythrocytic [Source:HGNC Symbol;Acc:HGNC:11274];microRNA 7855 [Source:HGNC Symbol;Acc:HGNC:50244]",{"v":1.59530273865552,"d":"1.60"},{"v":0.629953174162228,"d":"0.63"},{"v":2.53241479539667,"d":"2.53"},{"v":1.3405137295095,"d":"1.34"},{"v":0.107244335815591,"d":"0.11"},{"v":0.659227108313409,"d":"0.66"},"up","no"]
["MSTRG.9550","SIRPB1;SIRPD;AL049634.2;AL049634.1","ENST00000381603;ENST00000381605;MSTRG.9550.9;ENST00000381623;ENST00000279477;ENST00000262929;ENST00000381596;ENST00000564763;ENST00000565076;ENST00000565775;ENST00000563840;ENST00000381621;ENST00000453770;ENST00000566961;ENST00000567028","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005515(protein binding);GO:0005886(plasma membrane);GO:0070062(extracellular exosome);GO:0045087(innate immune response);GO:0005887(integral component of plasma membrane);GO:0043312(neutrophil degranulation);GO:0007165(signal transduction);GO:0007166(cell surface receptor signaling pathway);GO:0030667(secretory granule membrane);GO:0005576(extracellular region);GO:0005576(extracellular region)","04380(Osteoclast differentiation);04380(Osteoclast differentiation)","K06551","NA","signal regulatory protein beta 1 [Source:HGNC Symbol;Acc:HGNC:15928];signal regulatory protein delta [Source:HGNC Symbol;Acc:HGNC:16248]",{"v":5.9711483538398,"d":"5.97"},{"v":2.36148939729562,"d":"2.36"},{"v":2.52855183710669,"d":"2.53"},{"v":1.33831135504031,"d":"1.34"},{"v":0.107288317808692,"d":"0.11"},{"v":0.659227108313409,"d":"0.66"},"up","no"]
["ENSG00000150347","ARID5B","ENST00000279873;ENST00000309334","GO:0005634(nucleus);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0003713(transcription coactivator activity);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0005654(nucleoplasm);GO:0060612(adipose tissue development);GO:0044212(transcription regulatory region DNA binding);GO:0051091(positive regulation of sequence-specific DNA binding transcription factor activity);GO:0000977(RNA polymerase II regulatory region sequence-specific DNA binding);GO:0032452(histone demethylase activity);GO:0001227(transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding);GO:0001889(liver development);GO:0045892(negative regulation of transcription, DNA-templated);GO:0001822(kidney development);GO:0006807(nitrogen compound metabolic process);GO:0008584(male gonad development);GO:0008585(female gonad development);GO:0009791(post-embryonic development);GO:0010761(fibroblast migration);GO:0016577(histone demethylation);GO:0030325(adrenal gland development);GO:0035264(multicellular organism growth);GO:0045444(fat cell differentiation);GO:0048008(platelet-derived growth factor receptor signaling pathway);GO:0048468(cell development);GO:0048644(muscle organ morphogenesis);GO:0048705(skeletal system morphogenesis);GO:0060021(palate development);GO:0060325(face morphogenesis);GO:0060613(fat pad development);GO:1990830(cellular response to leukemia inhibitory factor);GO:1990830(cellular response to leukemia inhibitory factor)","NA","NA","NA","AT-rich interaction domain 5B [Source:HGNC Symbol;Acc:HGNC:17362]",{"v":2.15930330242528,"d":"2.16"},{"v":0.851354410950514,"d":"0.85"},{"v":2.53631539891181,"d":"2.54"},{"v":1.34273416036412,"d":"1.34"},{"v":0.107446145974489,"d":"0.11"},{"v":0.659303195813657,"d":"0.66"},"up","no"]
["MSTRG.314","EYA3","ENST00000540618;ENST00000373871;ENST00000436342;ENST00000468665;ENST00000373863;ENST00000471498","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0005654(nucleoplasm);GO:0016787(hydrolase activity);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0016569(covalent chromatin modification);GO:0004725(protein tyrosine phosphatase activity);GO:0035335(peptidyl-tyrosine dephosphorylation);GO:0005813(centrosome);GO:0007275(multicellular organism development);GO:0004721(phosphoprotein phosphatase activity);GO:0006281(DNA repair);GO:0006974(cellular response to DNA damage stimulus);GO:0005667(transcription factor complex);GO:0005515(protein binding);GO:0030154(cell differentiation);GO:0007601(visual perception);GO:0016576(histone dephosphorylation);GO:2001240(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand);GO:0009653(anatomical structure morphogenesis);GO:0045739(positive regulation of DNA repair);GO:0006302(double-strand break repair);GO:0010212(response to ionizing radiation);GO:0006470(protein dephosphorylation);GO:0006470(protein dephosphorylation)","NA","NA","NA","EYA transcriptional coactivator and phosphatase 3 [Source:HGNC Symbol;Acc:HGNC:3521]",{"v":2.15659535708777,"d":"2.16"},{"v":0.849017684096869,"d":"0.85"},{"v":2.54010652249466,"d":"2.54"},{"v":1.34488899945901,"d":"1.34"},{"v":0.107478568495297,"d":"0.11"},{"v":0.659303195813657,"d":"0.66"},"up","no"]
["MSTRG.10860","ZNF445;LINC00694","MSTRG.10860.5;ENST00000396077;ENST00000634610;ENST00000617032;ENST00000637612;ENST00000636468;ENST00000416124;ENST00000474600;ENST00000460529","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0005622(intracellular);GO:0070062(extracellular exosome);GO:0070062(extracellular exosome)","NA","NA","NA","zinc finger protein 445 [Source:HGNC Symbol;Acc:HGNC:21018];long intergenic non-protein coding RNA 694 [Source:HGNC Symbol;Acc:HGNC:44570]",{"v":1.58566939294888,"d":"1.59"},{"v":0.626284338806346,"d":"0.63"},{"v":2.53186818621563,"d":"2.53"},{"v":1.34020229732424,"d":"1.34"},{"v":0.107500617481513,"d":"0.11"},{"v":0.659303195813657,"d":"0.66"},"up","no"]
["MSTRG.11604","DANCR","ENST00000425653;ENST00000411630;ENST00000441504;ENST00000444958;ENST00000623036","NA","NA","NA","NA","differentiation antagonizing non-protein coding RNA [Source:HGNC Symbol;Acc:HGNC:28964]",{"v":3.26861162275711,"d":"3.27"},{"v":5.70694294223195,"d":"5.71"},{"v":0.572743000209281,"d":"0.57"},{"v":-0.804040173177694,"d":"-0.80"},{"v":0.107557581536538,"d":"0.11"},{"v":0.659303195813657,"d":"0.66"},"down","no"]
["ENSG00000179348","GATA2","ENST00000341105;ENST00000430265;ENST00000489987;ENST00000498200;ENST00000487848;ENST00000492608","GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0005634(nucleus);GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0005654(nucleoplasm);GO:0006355(regulation of transcription, DNA-templated);GO:0006366(transcription from RNA polymerase II promoter);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0043565(sequence-specific DNA binding);GO:0005515(protein binding);GO:0030097(hemopoiesis);GO:1902036(regulation of hematopoietic stem cell differentiation);GO:0005667(transcription factor complex);GO:0000977(RNA polymerase II regulatory region sequence-specific DNA binding);GO:0001228(transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding);GO:0006909(phagocytosis);GO:0050766(positive regulation of phagocytosis);GO:0045599(negative regulation of fat cell differentiation);GO:0070345(negative regulation of fat cell proliferation);GO:0007596(blood coagulation);GO:0003682(chromatin binding);GO:0008134(transcription factor binding);GO:0045766(positive regulation of angiogenesis);GO:0001085(RNA polymerase II transcription factor binding);GO:0070742(C2H2 zinc finger domain binding);GO:0035854(eosinophil fate commitment);GO:0000979(RNA polymerase II core promoter sequence-specific DNA binding);GO:0000980(RNA polymerase II distal enhancer sequence-specific DNA binding);GO:0001077(transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0001158(enhancer sequence-specific DNA binding);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0001655(urogenital system development);GO:0001709(cell fate determination);GO:0001764(neuron migration);GO:0001892(embryonic placenta development);GO:0007204(positive regulation of cytosolic calcium ion concentration);GO:0010725(regulation of primitive erythrocyte differentiation);GO:0021514(ventral spinal cord interneuron differentiation);GO:0021533(cell differentiation in hindbrain);GO:0021902(commitment of neuronal cell to specific neuron type in forebrain);GO:0021954(central nervous system neuron development);GO:0021983(pituitary gland development);GO:0030154(cell differentiation);GO:0030182(neuron differentiation);GO:0033993(response to lipid);GO:0035019(somatic stem cell population maintenance);GO:0035065(regulation of histone acetylation);GO:0042472(inner ear morphogenesis);GO:0043306(positive regulation of mast cell degranulation);GO:0045638(negative regulation of myeloid cell differentiation);GO:0045648(positive regulation of erythrocyte differentiation);GO:0045650(negative regulation of macrophage differentiation);GO:0045654(positive regulation of megakaryocyte differentiation);GO:0045666(positive regulation of neuron differentiation);GO:0045746(negative regulation of Notch signaling pathway);GO:0048469(cell maturation);GO:0048663(neuron fate commitment);GO:0048873(homeostasis of number of cells within a tissue);GO:0060100(positive regulation of phagocytosis, engulfment);GO:0060216(definitive hemopoiesis);GO:0060872(semicircular canal development);GO:0090102(cochlea development);GO:0097154(GABAergic neuron differentiation);GO:2000178(negative regulation of neural precursor cell proliferation);GO:2000977(regulation of forebrain neuron differentiation);GO:0043234(protein complex);GO:0043234(protein complex)","NA","NA","NA","GATA binding protein 2 [Source:HGNC Symbol;Acc:HGNC:4171]",{"v":4.05796283135232,"d":"4.06"},{"v":1.60152735366674,"d":"1.60"},{"v":2.53380800650173,"d":"2.53"},{"v":1.34130721170775,"d":"1.34"},{"v":0.107636508769006,"d":"0.11"},{"v":0.659303195813657,"d":"0.66"},"up","no"]
["MSTRG.2881","CD3D","ENST00000392884;ENST00000300692;ENST00000526561;MSTRG.2881.1;ENST00000529594;ENST00000534687","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0004888(transmembrane signaling receptor activity);GO:0007166(cell surface receptor signaling pathway);GO:0050776(regulation of immune response);GO:0005886(plasma membrane);GO:0061024(membrane organization);GO:0050852(T cell receptor signaling pathway);GO:0045059(positive thymic T cell selection);GO:0042101(T cell receptor complex);GO:0042105(alpha-beta T cell receptor complex);GO:0046982(protein heterodimerization activity);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0031295(T cell costimulation);GO:0042803(protein homodimerization activity);GO:0051260(protein homooligomerization);GO:0030665(clathrin-coated vesicle membrane);GO:0003713(transcription coactivator activity);GO:0030217(T cell differentiation);GO:0030217(T cell differentiation)","04640(Hematopoietic cell lineage);04660(T cell receptor signaling pathway);04658(Th1 and Th2 cell differentiation);04659(Th17 cell differentiation);05340(Primary immunodeficiency);05166(HTLV-I infection);05162(Measles);05142(Chagas disease (American trypanosomiasis));05142(Chagas disease (American trypanosomiasis))","K06450","NA","CD3d molecule [Source:HGNC Symbol;Acc:HGNC:1673]",{"v":34.5872008466859,"d":"34.59"},{"v":60.0011183469741,"d":"60.00"},{"v":0.576442603064084,"d":"0.58"},{"v":-0.79475113037063,"d":"-0.79"},{"v":0.107648146319059,"d":"0.11"},{"v":0.659303195813657,"d":"0.66"},"down","no"]
["MSTRG.8541","FAM228B;AC008073.3;FAM228A","ENST00000613899;ENST00000611138;ENST00000611917;ENST00000461972;ENST00000615135;ENST00000610442;ENST00000415196;ENST00000460686;ENST00000611127;ENST00000615575;ENST00000486967;ENST00000456591;ENST00000295150;ENST00000469867","NA","NA","NA","NA","family with sequence similarity 228 member B [Source:HGNC Symbol;Acc:HGNC:24736];family with sequence similarity 228 member A [Source:HGNC Symbol;Acc:HGNC:34418]",{"v":0.259268243745533,"d":"0.26"},{"v":0.471736822730522,"d":"0.47"},{"v":0.549603573969122,"d":"0.55"},{"v":-0.863536709125156,"d":"-0.86"},{"v":0.107807317708325,"d":"0.11"},{"v":0.659303195813657,"d":"0.66"},"down","no"]
["MSTRG.10986","ACY1;ABHD14A;ABHD14A-ACY1","ENST00000636358;ENST00000273596;ENST00000476351;ENST00000636029;ENST00000638136;ENST00000491318;ENST00000636490;ENST00000637034;ENST00000638077;ENST00000637778;ENST00000637746;ENST00000637102;ENST00000476854;ENST00000494478;ENST00000465121;ENST00000636646;ENST00000638096;ENST00000636085;ENST00000636089;ENST00000497864;ENST00000463721;ENST00000637149;ENST00000474575;ENST00000490244;ENST00000464587;ENST00000637199;ENST00000491470;ENST00000496679","GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0016787(hydrolase activity);GO:0008152(metabolic process);GO:0005515(protein binding);GO:0006508(proteolysis);GO:0008237(metallopeptidase activity);GO:0006520(cellular amino acid metabolic process);GO:0042802(identical protein binding);GO:0004046(aminoacylase activity);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0006805(xenobiotic metabolic process);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0006805(xenobiotic metabolic process)","00220(Arginine biosynthesis);00220(Arginine biosynthesis)","K14677","EC:3.5.1.14","aminoacylase 1 [Source:HGNC Symbol;Acc:HGNC:177];abhydrolase domain containing 14A [Source:HGNC Symbol;Acc:HGNC:24538];ABHD14A-ACY1 readthrough [Source:HGNC Symbol;Acc:HGNC:38856]",{"v":0.871380049557996,"d":"0.87"},{"v":1.53826957058666,"d":"1.54"},{"v":0.566467715555,"d":"0.57"},{"v":-0.819934359381615,"d":"-0.82"},{"v":0.10786688231847,"d":"0.11"},{"v":0.659303195813657,"d":"0.66"},"down","no"]
["ENSG00000137337","MDC1","ENST00000376406;ENST00000492462;ENST00000613547;ENST00000416571;ENST00000494654;ENST00000489540;ENST00000417033;ENST00000422266","GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005925(focal adhesion);GO:0005694(chromosome);GO:0005515(protein binding);GO:0006281(DNA repair);GO:0006974(cellular response to DNA damage stimulus);GO:0007049(cell cycle);GO:0016604(nuclear body);GO:0008022(protein C-terminus binding);GO:0006303(double-strand break repair via nonhomologous end joining);GO:0031573(intra-S DNA damage checkpoint);GO:0070975(FHA domain binding);GO:0070975(FHA domain binding)","NA","NA","NA","mediator of DNA damage checkpoint 1 [Source:HGNC Symbol;Acc:HGNC:21163]",{"v":1.76870115104167,"d":"1.77"},{"v":0.698519433407738,"d":"0.70"},{"v":2.53207150216714,"d":"2.53"},{"v":1.34031814503697,"d":"1.34"},{"v":0.107891249119931,"d":"0.11"},{"v":0.659303195813657,"d":"0.66"},"up","no"]
["MSTRG.6250","RPL13","ENST00000563270;ENST00000567815;ENST00000311528;ENST00000393099;ENST00000484610;ENST00000491523;ENST00000452368;ENST00000399461;ENST00000467736;ENST00000570149;ENST00000565571;ENST00000562879;ENST00000472354;ENST00000563749;ENST00000487034","GO:0003723(RNA binding);GO:0005634(nucleus);GO:0016020(membrane);GO:0006412(translation);GO:0030529(intracellular ribonucleoprotein complex);GO:0005622(intracellular);GO:0003735(structural constituent of ribosome);GO:0005840(ribosome);GO:0005515(protein binding);GO:0005829(cytosol);GO:0006413(translational initiation);GO:0006364(rRNA processing);GO:0000184(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay);GO:0019083(viral transcription);GO:0006614(SRP-dependent cotranslational protein targeting to membrane);GO:0022625(cytosolic large ribosomal subunit);GO:0022626(cytosolic ribosome);GO:0022626(cytosolic ribosome)","03010(Ribosome);03010(Ribosome)","K02873","NA","ribosomal protein L13 [Source:HGNC Symbol;Acc:HGNC:10303]",{"v":117.515394862281,"d":"117.52"},{"v":203.540743530298,"d":"203.54"},{"v":0.577355633196792,"d":"0.58"},{"v":-0.792467846728499,"d":"-0.79"},{"v":0.107964744901347,"d":"0.11"},{"v":0.659303195813657,"d":"0.66"},"down","no"]
["ENSG00000234771","SLC25A25-AS1","ENST00000418747","NA","NA","NA","NA","SLC25A25 antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:27844]",{"v":0.656818,"d":"0.66"},{"v":0.254005,"d":"0.25"},{"v":2.58584673530049,"d":"2.59"},{"v":1.37063676827478,"d":"1.37"},{"v":0.108032396081722,"d":"0.11"},{"v":0.659303195813657,"d":"0.66"},"up","no"]
["MSTRG.8718","AC007238.1","ENST00000434096","NA","NA","NA","NA",null,{"v":1.84006,"d":"1.84"},{"v":0.705699,"d":"0.71"},{"v":2.60742894633548,"d":"2.61"},{"v":1.38262793916263,"d":"1.38"},{"v":0.108081143412287,"d":"0.11"},{"v":0.659303195813657,"d":"0.66"},"up","no"]
["MSTRG.7727","KHSRP;MIR3940","ENST00000398148;MSTRG.7727.1;MSTRG.7727.2;ENST00000600480;ENST00000595112;ENST00000595223;ENST00000594745;ENST00000595258;ENST00000597704;ENST00000579148;ENST00000594496;ENST00000599642;ENST00000599395","GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0006397(mRNA processing);GO:0006810(transport);GO:0008380(RNA splicing);GO:0051028(mRNA transport);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005654(nucleoplasm);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0005829(cytosol);GO:0061158(3'-UTR-mediated mRNA destabilization);GO:0043488(regulation of mRNA stability);GO:0061014(positive regulation of mRNA catabolic process);GO:0000375(RNA splicing, via transesterification reactions);GO:0071345(cellular response to cytokine stimulus);GO:0045019(negative regulation of nitric oxide biosynthetic process);GO:0000178(exosome (RNase complex));GO:0035925(mRNA 3'-UTR AU-rich region binding);GO:0010586(miRNA metabolic process);GO:0003729(mRNA binding);GO:0006402(mRNA catabolic process);GO:2000628(regulation of miRNA metabolic process);GO:0010494(cytoplasmic stress granule);GO:0010494(cytoplasmic stress granule)","NA","NA","NA","KH-type splicing regulatory protein [Source:HGNC Symbol;Acc:HGNC:6316];microRNA 3940 [Source:HGNC Symbol;Acc:HGNC:38893]",{"v":9.97691802821801,"d":"9.98"},{"v":3.95284976884422,"d":"3.95"},{"v":2.52398107989193,"d":"2.52"},{"v":1.33570109572126,"d":"1.34"},{"v":0.108093105453479,"d":"0.11"},{"v":0.659303195813657,"d":"0.66"},"up","no"]
["ENSG00000101040","ZMYND8","ENST00000360911;ENST00000262975;ENST00000396281;ENST00000461685;ENST00000352431;ENST00000467200;ENST00000471951;ENST00000441977;ENST00000536340;ENST00000435836;ENST00000355972;ENST00000446994;ENST00000446894;ENST00000468376;ENST00000617418;ENST00000311275;ENST00000372023","GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0005515(protein binding);GO:0003682(chromatin binding);GO:0000977(RNA polymerase II regulatory region sequence-specific DNA binding);GO:0035064(methylated histone binding);GO:0001106(RNA polymerase II transcription corepressor activity);GO:0070577(lysine-acetylated histone binding);GO:0030336(negative regulation of cell migration);GO:0003712(transcription cofactor activity);GO:0070491(repressing transcription factor binding);GO:1903758(negative regulation of transcription from RNA polymerase II promoter by histone modification);GO:0047485(protein N-terminus binding);GO:0051491(positive regulation of filopodium assembly);GO:0060999(positive regulation of dendritic spine development);GO:0098815(modulation of excitatory postsynaptic potential);GO:1902897(regulation of postsynaptic density protein 95 clustering);GO:1902952(positive regulation of dendritic spine maintenance);GO:0005737(cytoplasm);GO:0043197(dendritic spine);GO:0043198(dendritic shaft);GO:0043198(dendritic shaft)","NA","NA","NA","zinc finger MYND-type containing 8 [Source:HGNC Symbol;Acc:HGNC:9397]",{"v":3.53465387462295,"d":"3.53"},{"v":1.39888345691803,"d":"1.40"},{"v":2.526767942778,"d":"2.53"},{"v":1.33729317390822,"d":"1.34"},{"v":0.108145994730129,"d":"0.11"},{"v":0.659303195813657,"d":"0.66"},"up","no"]
["ENSG00000198793","MTOR","ENST00000361445;ENST00000376838;ENST00000495435;ENST00000455339;ENST00000473471","GO:0000166(nucleotide binding);GO:0004674(protein serine/threonine kinase activity);GO:0005524(ATP binding);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0006468(protein phosphorylation);GO:0044877(macromolecular complex binding);GO:0010718(positive regulation of epithelial to mesenchymal transition);GO:1903691(positive regulation of wound healing, spreading of epidermal cells);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005794(Golgi apparatus);GO:0005765(lysosomal membrane);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005739(mitochondrion);GO:0005515(protein binding);GO:0007165(signal transduction);GO:0000139(Golgi membrane);GO:0005741(mitochondrial outer membrane);GO:0045727(positive regulation of translation);GO:0005764(lysosome);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0043231(intracellular membrane-bounded organelle);GO:0001934(positive regulation of protein phosphorylation);GO:0010628(positive regulation of gene expression);GO:0032956(regulation of actin cytoskeleton organization);GO:0012505(endomembrane system);GO:0009267(cellular response to starvation);GO:0031090(organelle membrane);GO:0016605(PML body);GO:0038111(interleukin-7-mediated signaling pathway);GO:0048015(phosphatidylinositol-mediated signaling);GO:0005942(phosphatidylinositol 3-kinase complex);GO:0030163(protein catabolic process);GO:0071456(cellular response to hypoxia);GO:0006950(response to stress);GO:0016049(cell growth);GO:0051219(phosphoprotein binding);GO:1900034(regulation of cellular response to heat);GO:0031295(T cell costimulation);GO:0031931(TORC1 complex);GO:0031932(TORC2 complex);GO:0007050(cell cycle arrest);GO:0016241(regulation of macroautophagy);GO:0046889(positive regulation of lipid biosynthetic process);GO:0006281(DNA repair);GO:0018105(peptidyl-serine phosphorylation);GO:0031669(cellular response to nutrient levels);GO:0045670(regulation of osteoclast differentiation);GO:0045945(positive regulation of transcription from RNA polymerase III promoter);GO:0010507(negative regulation of autophagy);GO:0051549(positive regulation of keratinocyte migration);GO:1901838(positive regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter);GO:0031929(TOR signaling);GO:0034198(cellular response to amino acid starvation);GO:0043276(anoikis);GO:0007584(response to nutrient);GO:0001030(RNA polymerase III type 1 promoter DNA binding);GO:0001031(RNA polymerase III type 2 promoter DNA binding);GO:0001032(RNA polymerase III type 3 promoter DNA binding);GO:0001156(TFIIIC-class transcription factor binding);GO:0004672(protein kinase activity);GO:0019901(protein kinase binding);GO:0019904(protein domain specific binding);GO:0043022(ribosome binding);GO:0001932(regulation of protein phosphorylation);GO:0001933(negative regulation of protein phosphorylation);GO:0001938(positive regulation of endothelial cell proliferation);GO:0003007(heart morphogenesis);GO:0003179(heart valve morphogenesis);GO:0005979(regulation of glycogen biosynthetic process);GO:0006109(regulation of carbohydrate metabolic process);GO:0006112(energy reserve metabolic process);GO:0006207('de novo' pyrimidine nucleobase biosynthetic process);GO:0007281(germ cell development);GO:0007420(brain development);GO:0007569(cell aging);GO:0007616(long-term memory);GO:0008361(regulation of cell size);GO:0008542(visual learning);GO:0009791(post-embryonic development);GO:0010592(positive regulation of lamellipodium assembly);GO:0010831(positive regulation of myotube differentiation);GO:0010942(positive regulation of cell death);GO:0010976(positive regulation of neuron projection development);GO:0014042(positive regulation of neuron maturation);GO:0014736(negative regulation of muscle atrophy);GO:0016242(negative regulation of macroautophagy);GO:0018107(peptidyl-threonine phosphorylation);GO:0021510(spinal cord development);GO:0030030(cell projection organization);GO:0030838(positive regulation of actin filament polymerization);GO:0031397(negative regulation of protein ubiquitination);GO:0031529(ruffle organization);GO:0031641(regulation of myelination);GO:0031998(regulation of fatty acid beta-oxidation);GO:0032095(regulation of response to food);GO:0032868(response to insulin);GO:0035176(social behavior);GO:0035264(multicellular organism growth);GO:0038202(TORC1 signaling);GO:0040007(growth);GO:0042060(wound healing);GO:0042220(response to cocaine);GO:0043087(regulation of GTPase activity);GO:0043200(response to amino acid);GO:0043278(response to morphine);GO:0043610(regulation of carbohydrate utilization);GO:0045429(positive regulation of nitric oxide biosynthetic process);GO:0045792(negative regulation of cell size);GO:0045859(regulation of protein kinase activity);GO:0046777(protein autophosphorylation);GO:0048255(mRNA stabilization);GO:0048661(positive regulation of smooth muscle cell proliferation);GO:0048714(positive regulation of oligodendrocyte differentiation);GO:0048738(cardiac muscle tissue development);GO:0050731(positive regulation of peptidyl-tyrosine phosphorylation);GO:0050769(positive regulation of neurogenesis);GO:0050882(voluntary musculoskeletal movement);GO:0051496(positive regulation of stress fiber assembly);GO:0051534(negative regulation of NFAT protein import into nucleus);GO:0051896(regulation of protein kinase B signaling);GO:0051897(positive regulation of protein kinase B signaling);GO:0055006(cardiac cell development);GO:0055013(cardiac muscle cell development);GO:0060048(cardiac muscle contraction);GO:0060135(maternal process involved in female pregnancy);GO:0060252(positive regulation of glial cell proliferation);GO:0060999(positive regulation of dendritic spine development);GO:0061051(positive regulation of cell growth involved in cardiac muscle cell development);GO:0071230(cellular response to amino acid stimulus);GO:0071233(cellular response to leucine);GO:0090335(regulation of brown fat cell differentiation);GO:0090559(regulation of membrane permeability);GO:1901216(positive regulation of neuron death);GO:1904000(positive regulation of eating behavior);GO:1904056(positive regulation of cholangiocyte proliferation);GO:1904058(positive regulation of sensory perception of pain);GO:1904193(negative regulation of cholangiocyte apoptotic process);GO:1904197(positive regulation of granulosa cell proliferation);GO:1904206(positive regulation of skeletal muscle hypertrophy);GO:1904213(negative regulation of iodide transmembrane transport);GO:1990253(cellular response to leucine starvation);GO:0030425(dendrite);GO:0032991(macromolecular complex);GO:0043025(neuronal cell body);GO:0043025(neuronal cell body)","04012(ErbB signaling pathway);04371(Apelin signaling pathway);04630(Jak-STAT signaling pathway);04066(HIF-1 signaling pathway);04072(Phospholipase D signaling pathway);04151(PI3K-Akt signaling pathway);04152(AMPK signaling pathway);04150(mTOR signaling pathway);04140(Autophagy - animal);04136(Autophagy - other eukaryotes);04218(Cellular senescence);04659(Th17 cell differentiation);04910(Insulin signaling pathway);04920(Adipocytokine signaling pathway);04919(Thyroid hormone signaling pathway);04211(Longevity regulating pathway - mammal);04213(Longevity regulating pathway - multiple species);05200(Pathways in cancer);05230(Central carbon metabolism in cancer);05231(Choline metabolism in cancer);05206(MicroRNAs in cancer);05205(Proteoglycans in cancer);05212(Pancreatic cancer);05225(Hepatocellular carcinoma);05226(Gastric cancer);05214(Glioma);05221(Acute myeloid leukemia);05215(Prostate cancer);05224(Breast cancer);04930(Type II diabetes mellitus);04931(Insulin resistance);05167(Kaposi's sarcoma-associated herpesvirus infection);05165(Human papillomavirus infection);01521(EGFR tyrosine kinase inhibitor resistance);01522(Endocrine resistance);01522(Endocrine resistance)","K07203","EC:2.7.11.1","mechanistic target of rapamycin [Source:HGNC Symbol;Acc:HGNC:3942]",{"v":4.11711708499051,"d":"4.12"},{"v":1.6338755747999,"d":"1.63"},{"v":2.51984737913395,"d":"2.52"},{"v":1.33333635593373,"d":"1.33"},{"v":0.108152293810817,"d":"0.11"},{"v":0.659303195813657,"d":"0.66"},"up","no"]
["MSTRG.5098","RFX7","ENST00000559447;MSTRG.5098.2;ENST00000560792","GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0005634(nucleus);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0006357(regulation of transcription from RNA polymerase II promoter)","NA","NA","NA","regulatory factor X7 [Source:HGNC Symbol;Acc:HGNC:25777]",{"v":2.32886164854015,"d":"2.33"},{"v":0.922130793065693,"d":"0.92"},{"v":2.52552204747189,"d":"2.53"},{"v":1.3365816363601,"d":"1.34"},{"v":0.10824811300162,"d":"0.11"},{"v":0.65954109983621,"d":"0.66"},"up","no"]
["MSTRG.15160","PRKX","ENST00000262848;ENST00000462736;ENST00000425240;ENST00000496648","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0007155(cell adhesion);GO:0005515(protein binding);GO:0007275(multicellular organism development);GO:0030154(cell differentiation);GO:0001525(angiogenesis);GO:0001935(endothelial cell proliferation);GO:0030334(regulation of cell migration);GO:0046777(protein autophosphorylation);GO:0030155(regulation of cell adhesion);GO:0043542(endothelial cell migration);GO:0031589(cell-substrate adhesion);GO:0018105(peptidyl-serine phosphorylation);GO:0004691(cAMP-dependent protein kinase activity);GO:0030099(myeloid cell differentiation);GO:0060562(epithelial tube morphogenesis);GO:0060993(kidney morphogenesis);GO:2000696(regulation of epithelial cell differentiation involved in kidney development);GO:2000696(regulation of epithelial cell differentiation involved in kidney development)","NA","NA","NA","protein kinase, X-linked [Source:HGNC Symbol;Acc:HGNC:9441]",{"v":8.42664818288902,"d":"8.43"},{"v":3.34587114228146,"d":"3.35"},{"v":2.51852143270022,"d":"2.52"},{"v":1.33257700843058,"d":"1.33"},{"v":0.10850566631965,"d":"0.11"},{"v":0.660479053360357,"d":"0.66"},"up","no"]
["ENSG00000214199","EEF1A1P12","ENST00000443590","NA","NA","NA","NA","eukaryotic translation elongation factor 1 alpha 1 pseudogene 12 [Source:HGNC Symbol;Acc:HGNC:3195]",{"v":0.642024,"d":"0.64"},{"v":1.171724,"d":"1.17"},{"v":0.547931082746449,"d":"0.55"},{"v":-0.867933648476136,"d":"-0.87"},{"v":0.108515804168739,"d":"0.11"},{"v":0.660479053360357,"d":"0.66"},"down","no"]
["MSTRG.13227","FAM26F","ENST00000368606;ENST00000368605;ENST00000368604","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0098655(cation transmembrane transport);GO:0006811(ion transport);GO:0005887(integral component of plasma membrane);GO:0034220(ion transmembrane transport);GO:0005261(cation channel activity);GO:0005261(cation channel activity)","NA","NA","NA","family with sequence similarity 26 member F [Source:HGNC Symbol;Acc:HGNC:33391]",{"v":3.22331470184255,"d":"3.22"},{"v":5.66880584338358,"d":"5.67"},{"v":0.568605591882227,"d":"0.57"},{"v":-0.814499807794029,"d":"-0.81"},{"v":0.10858426589527,"d":"0.11"},{"v":0.660544039588157,"d":"0.66"},"down","no"]
["MSTRG.6073","CHTF8","ENST00000448552;ENST00000519534;ENST00000306585;ENST00000519520;ENST00000520529;ENST00000523421;ENST00000522091;ENST00000522497;ENST00000518041;ENST00000567763;ENST00000398235","GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0070062(extracellular exosome);GO:0007064(mitotic sister chromatid cohesion);GO:0031390(Ctf18 RFC-like complex);GO:0003677(DNA binding);GO:0007049(cell cycle);GO:0006260(DNA replication);GO:0043142(single-stranded DNA-dependent ATPase activity);GO:0003689(DNA clamp loader activity);GO:1900264(positive regulation of DNA-directed DNA polymerase activity);GO:1900264(positive regulation of DNA-directed DNA polymerase activity)","NA","NA","NA","chromosome transmission fidelity factor 8 [Source:HGNC Symbol;Acc:HGNC:24353]",{"v":11.6096899512267,"d":"11.61"},{"v":4.59963226426249,"d":"4.60"},{"v":2.52404742036225,"d":"2.52"},{"v":1.33573901510604,"d":"1.34"},{"v":0.108647969035751,"d":"0.11"},{"v":0.660544039588157,"d":"0.66"},"up","no"]
["MSTRG.15491","SSR4","ENST00000370086;ENST00000370087;ENST00000486204;ENST00000370085;ENST00000482902;ENST00000460616;ENST00000485612;ENST00000447375;ENST00000471880;ENST00000320857;ENST00000471724","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0070062(extracellular exosome);GO:0005784(Sec61 translocon complex);GO:0005784(Sec61 translocon complex)","04141(Protein processing in endoplasmic reticulum);04141(Protein processing in endoplasmic reticulum)","K04571","NA","signal sequence receptor subunit 4 [Source:HGNC Symbol;Acc:HGNC:11326]",{"v":5.59715377342048,"d":"5.60"},{"v":9.69379436557734,"d":"9.69"},{"v":0.577395554551474,"d":"0.58"},{"v":-0.792368094780097,"d":"-0.79"},{"v":0.108739641291505,"d":"0.11"},{"v":0.660544039588157,"d":"0.66"},"down","no"]
["MSTRG.8116","EIF3K","ENST00000248342;ENST00000545173;ENST00000588422;ENST00000588299;ENST00000591409;ENST00000614624;ENST00000586932;ENST00000593062;ENST00000592558;ENST00000593149;ENST00000586513;ENST00000590134","GO:0005737(cytoplasm);GO:0003743(translation initiation factor activity);GO:0005852(eukaryotic translation initiation factor 3 complex);GO:0005829(cytosol);GO:0043022(ribosome binding);GO:0006446(regulation of translational initiation);GO:0006413(translational initiation);GO:0005634(nucleus);GO:0016020(membrane);GO:0006412(translation);GO:0005515(protein binding);GO:0070062(extracellular exosome);GO:0003723(RNA binding);GO:0001731(formation of translation preinitiation complex);GO:0016282(eukaryotic 43S preinitiation complex);GO:0033290(eukaryotic 48S preinitiation complex);GO:0033290(eukaryotic 48S preinitiation complex)","NA","NA","NA","eukaryotic translation initiation factor 3 subunit K [Source:HGNC Symbol;Acc:HGNC:24656]",{"v":24.1169685257327,"d":"24.12"},{"v":41.7334918959971,"d":"41.73"},{"v":0.577880436792443,"d":"0.58"},{"v":-0.79115706425444,"d":"-0.79"},{"v":0.108785170383003,"d":"0.11"},{"v":0.660544039588157,"d":"0.66"},"down","no"]
["ENSG00000130818","ZNF426","ENST00000253115;ENST00000535489;ENST00000589289;ENST00000593003","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0005622(intracellular);GO:0005515(protein binding);GO:0005515(protein binding)","NA","NA","NA","zinc finger protein 426 [Source:HGNC Symbol;Acc:HGNC:20725]",{"v":1.09216371093439,"d":"1.09"},{"v":0.43116973214049,"d":"0.43"},{"v":2.53302500041567,"d":"2.53"},{"v":1.34086131621256,"d":"1.34"},{"v":0.108855299211898,"d":"0.11"},{"v":0.660544039588157,"d":"0.66"},"up","no"]
["MSTRG.12021","RPL37","ENST00000274242;ENST00000508493;ENST00000507642;ENST00000504562;MSTRG.12021.3;MSTRG.12021.1;ENST00000509877","GO:0003723(RNA binding);GO:0006412(translation);GO:0046872(metal ion binding);GO:0030529(intracellular ribonucleoprotein complex);GO:0005622(intracellular);GO:0003735(structural constituent of ribosome);GO:0005840(ribosome);GO:0005829(cytosol);GO:0019843(rRNA binding);GO:0006413(translational initiation);GO:0006364(rRNA processing);GO:0000184(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay);GO:0019083(viral transcription);GO:0006614(SRP-dependent cotranslational protein targeting to membrane);GO:0022625(cytosolic large ribosomal subunit);GO:0022625(cytosolic large ribosomal subunit)","03010(Ribosome);03010(Ribosome)","K02922","NA","ribosomal protein L37 [Source:HGNC Symbol;Acc:HGNC:10347]",{"v":41.709280238165,"d":"41.71"},{"v":72.0995465128111,"d":"72.10"},{"v":0.578495736179892,"d":"0.58"},{"v":-0.789621768942315,"d":"-0.79"},{"v":0.108901983454168,"d":"0.11"},{"v":0.660544039588157,"d":"0.66"},"down","no"]
["MSTRG.8324","PRMT1;ADM5","ENST00000454376;ENST00000529284;ENST00000527412;ENST00000524771;ENST00000420022;ENST00000525616;ENST00000526224;ENST00000529836;ENST00000527866;ENST00000529650;ENST00000534676;ENST00000530361;ENST00000528126;ENST00000391851;ENST00000534280;ENST00000530070;MSTRG.8324.5;ENST00000525915;ENST00000528623","GO:0008168(methyltransferase activity);GO:0016740(transferase activity);GO:0032259(methylation);GO:0006479(protein methylation);GO:0045648(positive regulation of erythrocyte differentiation);GO:1900745(positive regulation of p38MAPK cascade);GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005515(protein binding);GO:0005654(nucleoplasm);GO:0042802(identical protein binding);GO:0006355(regulation of transcription, DNA-templated);GO:0006977(DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest);GO:0008284(positive regulation of cell proliferation);GO:0019899(enzyme binding);GO:0007166(cell surface receptor signaling pathway);GO:0031175(neuron projection development);GO:0045652(regulation of megakaryocyte differentiation);GO:0008327(methyl-CpG binding);GO:0016274(protein-arginine N-methyltransferase activity);GO:0044020(histone methyltransferase activity (H4-R3 specific));GO:0018216(peptidyl-arginine methylation);GO:0043985(histone H4-R3 methylation);GO:0034709(methylosome);GO:0042054(histone methyltransferase activity);GO:0046985(positive regulation of hemoglobin biosynthetic process);GO:0019919(peptidyl-arginine methylation, to asymmetrical-dimethyl arginine);GO:0035246(peptidyl-arginine N-methylation);GO:0048273(mitogen-activated protein kinase p38 binding);GO:0045653(negative regulation of megakaryocyte differentiation);GO:0016571(histone methylation);GO:0008276(protein methyltransferase activity);GO:0035242(protein-arginine omega-N asymmetric methyltransferase activity);GO:0008170(N-methyltransferase activity);GO:0001701(in utero embryonic development);GO:0005576(extracellular region);GO:0003674(molecular_function);GO:0008150(biological_process);GO:0005575(cellular_component);GO:0001701(in utero embryonic development)","04068(FoxO signaling pathway);04922(Glucagon signaling pathway);04922(Glucagon signaling pathway)","K11434","EC:2.1.1.319","protein arginine methyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:5187];adrenomedullin 5 (putative) [Source:HGNC Symbol;Acc:HGNC:27293]",{"v":4.11479325816888,"d":"4.11"},{"v":7.12138324522808,"d":"7.12"},{"v":0.577808147163844,"d":"0.58"},{"v":-0.791337548669138,"d":"-0.79"},{"v":0.108970769663997,"d":"0.11"},{"v":0.660544039588157,"d":"0.66"},"down","no"]
["MSTRG.4626","RIN3","ENST00000555589;ENST00000556418;ENST00000216487;MSTRG.4626.10;ENST00000553959;ENST00000557762;ENST00000553992;ENST00000554888;ENST00000555891;ENST00000555908","GO:0005737(cytoplasm);GO:0007165(signal transduction);GO:0043547(positive regulation of GTPase activity);GO:0005515(protein binding);GO:0031410(cytoplasmic vesicle);GO:0005096(GTPase activator activity);GO:0005768(endosome);GO:0005829(cytosol);GO:0006897(endocytosis);GO:0017112(Rab guanyl-nucleotide exchange factor activity);GO:0061024(membrane organization);GO:0005769(early endosome);GO:0017137(Rab GTPase binding);GO:0017137(Rab GTPase binding)","NA","NA","NA","Ras and Rab interactor 3 [Source:HGNC Symbol;Acc:HGNC:18751]",{"v":11.846834908819,"d":"11.85"},{"v":4.71416667261245,"d":"4.71"},{"v":2.51302843780316,"d":"2.51"},{"v":1.32942699706237,"d":"1.33"},{"v":0.109042518101476,"d":"0.11"},{"v":0.660544039588157,"d":"0.66"},"up","no"]
["MSTRG.12145","IQGAP2","ENST00000274364;ENST00000514579;ENST00000512256;ENST00000508410;ENST00000512383;ENST00000509074;ENST00000504558;ENST00000513534;ENST00000502745;ENST00000509741","GO:0005737(cytoplasm);GO:0007165(signal transduction);GO:0043087(regulation of GTPase activity);GO:0005886(plasma membrane);GO:0005516(calmodulin binding);GO:0005829(cytosol);GO:0051015(actin filament binding);GO:0030027(lamellipodium);GO:0030175(filopodium);GO:0070062(extracellular exosome);GO:0031941(filamentous actin);GO:0034314(Arp2/3 complex-mediated actin nucleation);GO:0005547(phosphatidylinositol-3,4,5-trisphosphate binding);GO:0043312(neutrophil degranulation);GO:0009986(cell surface);GO:0030667(secretory granule membrane);GO:0015629(actin cytoskeleton);GO:0005095(GTPase inhibitor activity);GO:0034260(negative regulation of GTPase activity);GO:0003779(actin binding);GO:0017048(Rho GTPase binding);GO:0048365(Rac GTPase binding);GO:0070493(thrombin-activated receptor signaling pathway);GO:0071933(Arp2/3 complex binding);GO:0005902(microvillus);GO:0005902(microvillus)","04810(Regulation of actin cytoskeleton);04810(Regulation of actin cytoskeleton)","K05767","NA","IQ motif containing GTPase activating protein 2 [Source:HGNC Symbol;Acc:HGNC:6111]",{"v":16.0249043655111,"d":"16.02"},{"v":6.38000781553644,"d":"6.38"},{"v":2.51173741926893,"d":"2.51"},{"v":1.32868565064703,"d":"1.33"},{"v":0.109076120146253,"d":"0.11"},{"v":0.660544039588157,"d":"0.66"},"up","no"]
["MSTRG.8936","IGKV4-1","ENST00000390243","GO:0016020(membrane);GO:0005886(plasma membrane);GO:0005576(extracellular region);GO:0006508(proteolysis);GO:0006955(immune response);GO:0002376(immune system process);GO:0002377(immunoglobulin production);GO:0003823(antigen binding);GO:0002250(adaptive immune response);GO:0004252(serine-type endopeptidase activity);GO:0006898(receptor-mediated endocytosis);GO:0006956(complement activation);GO:0006958(complement activation, classical pathway);GO:0030449(regulation of complement activation);GO:0038095(Fc-epsilon receptor signaling pathway);GO:0038096(Fc-gamma receptor signaling pathway involved in phagocytosis);GO:0050776(regulation of immune response);GO:0050900(leukocyte migration);GO:0070062(extracellular exosome);GO:0072562(blood microparticle)","NA","NA","NA","immunoglobulin kappa variable 4-1 [Source:HGNC Symbol;Acc:HGNC:5834]",{"v":22.765705,"d":"22.77"},{"v":39.469994,"d":"39.47"},{"v":0.576785114282004,"d":"0.58"},{"v":-0.79389416302127,"d":"-0.79"},{"v":0.109095278388882,"d":"0.11"},{"v":0.660544039588157,"d":"0.66"},"down","no"]
["ENSG00000151116","UEVLD","ENST00000396197;ENST00000539569;ENST00000300038;ENST00000320750;ENST00000379387;ENST00000396196;ENST00000543987;ENST00000490736;ENST00000541984;ENST00000535340","GO:0015031(protein transport);GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0003824(catalytic activity);GO:0005975(carbohydrate metabolic process);GO:0016616(oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor);GO:0006464(cellular protein modification process);GO:0019752(carboxylic acid metabolic process);GO:0003674(molecular_function);GO:0008150(biological_process);GO:0070062(extracellular exosome);GO:0070062(extracellular exosome)","NA","NA","NA","UEV and lactate/malate dehyrogenase domains [Source:HGNC Symbol;Acc:HGNC:30866]",{"v":1.77442779728014,"d":"1.77"},{"v":0.702790297914778,"d":"0.70"},{"v":2.52483251767273,"d":"2.52"},{"v":1.33618769125579,"d":"1.34"},{"v":0.109194794403935,"d":"0.11"},{"v":0.660802057015579,"d":"0.66"},"up","no"]
["MSTRG.12826","DHX16","ENST00000376442;ENST00000376437;ENST00000415603;ENST00000480966","GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0016787(hydrolase activity);GO:0004386(helicase activity);GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0006397(mRNA processing);GO:0008380(RNA splicing);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0004004(ATP-dependent RNA helicase activity);GO:0000398(mRNA splicing, via spliceosome);GO:0005681(spliceosomal complex);GO:0016887(ATPase activity);GO:0003724(RNA helicase activity);GO:0003724(RNA helicase activity)","03040(Spliceosome);03040(Spliceosome)","K12813","EC:3.6.4.13","DEAH-box helicase 16 [Source:HGNC Symbol;Acc:HGNC:2739]",{"v":7.6201919755489,"d":"7.62"},{"v":3.02591527744511,"d":"3.03"},{"v":2.51830975981023,"d":"2.52"},{"v":1.33245574987846,"d":"1.33"},{"v":0.109292543740061,"d":"0.11"},{"v":0.660848365406404,"d":"0.66"},"up","no"]
["ENSG00000247828","TMEM161B-AS1","ENST00000504769;ENST00000506584;ENST00000496733;ENST00000512724;ENST00000501715;ENST00000507736;ENST00000510087;ENST00000504636;ENST00000513011","NA","NA","NA","NA","TMEM161B antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:43839]",{"v":0.5974855613877,"d":"0.60"},{"v":0.223202947510701,"d":"0.22"},{"v":2.67687128710097,"d":"2.68"},{"v":1.42054777105735,"d":"1.42"},{"v":0.109316258498726,"d":"0.11"},{"v":0.660848365406404,"d":"0.66"},"up","no"]
["MSTRG.3340","ARF3;FKBP11;AC073610.1;AC073610.3","ENST00000256682;ENST00000550765;ENST00000444214;ENST00000447318;ENST00000472621;ENST00000553027;ENST00000546671;ENST00000547789;ENST00000539611;ENST00000551094;ENST00000453172;ENST00000485410;ENST00000489971;ENST00000551807;ENST00000552878;ENST00000536283;ENST00000398092;ENST00000541959;ENST00000549084;ENST00000545855;ENST00000551694;ENST00000541236","GO:0006810(transport);GO:0005737(cytoplasm);GO:0015031(protein transport);GO:0005525(GTP binding);GO:0007264(small GTPase mediated signal transduction);GO:0000166(nucleotide binding);GO:0005794(Golgi apparatus);GO:0005622(intracellular);GO:0048471(perinuclear region of cytoplasm);GO:0016192(vesicle-mediated transport);GO:0070062(extracellular exosome);GO:0003924(GTPase activity);GO:0006661(phosphatidylinositol biosynthetic process);GO:0000139(Golgi membrane);GO:0006890(retrograde vesicle-mediated transport, Golgi to ER);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016853(isomerase activity);GO:0003755(peptidyl-prolyl cis-trans isomerase activity);GO:0000413(protein peptidyl-prolyl isomerization);GO:0005528(FK506 binding);GO:0061077(chaperone-mediated protein folding);GO:0006890(retrograde vesicle-mediated transport, Golgi to ER)","04144(Endocytosis);04144(Endocytosis)","K07938","NA","ADP ribosylation factor 3 [Source:HGNC Symbol;Acc:HGNC:654];FK506 binding protein 11 [Source:HGNC Symbol;Acc:HGNC:18624]",{"v":5.55028282555024,"d":"5.55"},{"v":9.59051413933014,"d":"9.59"},{"v":0.578726306527077,"d":"0.58"},{"v":-0.789046870282272,"d":"-0.79"},{"v":0.109558935761143,"d":"0.11"},{"v":0.661970822577602,"d":"0.66"},"down","no"]
["MSTRG.13799","LAMTOR4","ENST00000441173;ENST00000341942;ENST00000466498;ENST00000468582;ENST00000474831;ENST00000473459;ENST00000488241;ENST00000474141;ENST00000494136;ENST00000490633;ENST00000488338;ENST00000460732","GO:0043231(intracellular membrane-bounded organelle);GO:0043547(positive regulation of GTPase activity);GO:0005515(protein binding);GO:0005764(lysosome);GO:0005085(guanyl-nucleotide exchange factor activity);GO:0032008(positive regulation of TOR signaling);GO:0071230(cellular response to amino acid stimulus);GO:0071986(Ragulator complex);GO:0005765(lysosomal membrane);GO:0008361(regulation of cell size);GO:0032947(protein complex scaffold);GO:0007050(cell cycle arrest);GO:0016241(regulation of macroautophagy);GO:0061462(protein localization to lysosome);GO:0061462(protein localization to lysosome)","04150(mTOR signaling pathway);04150(mTOR signaling pathway)","K20399","NA","late endosomal/lysosomal adaptor, MAPK and MTOR activator 4 [Source:HGNC Symbol;Acc:HGNC:33772]",{"v":16.0225990278926,"d":"16.02"},{"v":27.7129838811983,"d":"27.71"},{"v":0.578162174689642,"d":"0.58"},{"v":-0.790453868937713,"d":"-0.79"},{"v":0.109682177969338,"d":"0.11"},{"v":0.662370843867875,"d":"0.66"},"down","no"]
["ENSG00000108064","TFAM","ENST00000487519;ENST00000373895;ENST00000373899","GO:0003723(RNA binding);GO:0005634(nucleus);GO:0006366(transcription from RNA polymerase II promoter);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0005739(mitochondrion);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0005515(protein binding);GO:0045893(positive regulation of transcription, DNA-templated);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:0005829(cytosol);GO:0005759(mitochondrial matrix);GO:0003682(chromatin binding);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0001223(transcription coactivator binding);GO:0031072(heat shock protein binding);GO:0006390(transcription from mitochondrial promoter);GO:0033108(mitochondrial respiratory chain complex assembly);GO:0042645(mitochondrial nucleoid);GO:0006391(transcription initiation from mitochondrial promoter);GO:0007005(mitochondrion organization);GO:0001077(transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0008301(DNA binding, bending);GO:0006261(DNA-dependent DNA replication);GO:0006356(regulation of transcription from RNA polymerase I promoter);GO:0070363(mitochondrial light strand promoter sense binding);GO:0070363(mitochondrial light strand promoter sense binding)","04371(Apelin signaling pathway);05016(Huntington's disease);05016(Huntington's disease)","K11830","NA","transcription factor A, mitochondrial [Source:HGNC Symbol;Acc:HGNC:11741]",{"v":1.47317035105244,"d":"1.47"},{"v":2.55993675651088,"d":"2.56"},{"v":0.575471385105751,"d":"0.58"},{"v":-0.797183901703417,"d":"-0.80"},{"v":0.10985542807187,"d":"0.11"},{"v":0.662803524698305,"d":"0.66"},"down","no"]
["MSTRG.5738","UQCRC2","ENST00000563711;ENST00000268379;ENST00000565464;ENST00000630839;ENST00000567757;ENST00000563898;ENST00000565331;ENST00000561798;ENST00000567597;ENST00000561553;ENST00000567810;ENST00000564095;ENST00000618892","GO:0016020(membrane);GO:0005654(nucleoplasm);GO:0055114(oxidation-reduction process);GO:0005739(mitochondrion);GO:0005743(mitochondrial inner membrane);GO:0046872(metal ion binding);GO:0003824(catalytic activity);GO:0005515(protein binding);GO:0006508(proteolysis);GO:0004222(metalloendopeptidase activity);GO:0070469(respiratory chain);GO:0070062(extracellular exosome);GO:0005751(mitochondrial respiratory chain complex IV);GO:0008270(zinc ion binding);GO:0006122(mitochondrial electron transport, ubiquinol to cytochrome c);GO:0009060(aerobic respiration);GO:0005750(mitochondrial respiratory chain complex III);GO:0006119(oxidative phosphorylation);GO:0032403(protein complex binding);GO:0006627(protein processing involved in protein targeting to mitochondrion);GO:0043209(myelin sheath);GO:0043209(myelin sheath)","00190(Oxidative phosphorylation);04260(Cardiac muscle contraction);05010(Alzheimer's disease);05012(Parkinson's disease);05016(Huntington's disease);04932(Non-alcoholic fatty liver disease (NAFLD));04932(Non-alcoholic fatty liver disease (NAFLD))","K00415","NA","ubiquinol-cytochrome c reductase core protein II [Source:HGNC Symbol;Acc:HGNC:12586]",{"v":12.2330690178263,"d":"12.23"},{"v":21.1244987811003,"d":"21.12"},{"v":0.579093929971536,"d":"0.58"},{"v":-0.788130720224881,"d":"-0.79"},{"v":0.109888749662187,"d":"0.11"},{"v":0.662803524698305,"d":"0.66"},"down","no"]
["ENSG00000186001","LRCH3","ENST00000425562;ENST00000461674;ENST00000414675;ENST00000466845;ENST00000334859;ENST00000493726;ENST00000494069;ENST00000466054;ENST00000476664;ENST00000438796;ENST00000428136;ENST00000433298","GO:0005829(cytosol);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0005886(plasma membrane);GO:0007165(signal transduction);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016021(integral component of membrane)","NA","NA","NA","leucine rich repeats and calponin homology domain containing 3 [Source:HGNC Symbol;Acc:HGNC:28637]",{"v":1.39951649529235,"d":"1.40"},{"v":0.554154418704011,"d":"0.55"},{"v":2.52549911731349,"d":"2.53"},{"v":1.33656853753325,"d":"1.34"},{"v":0.109925048529143,"d":"0.11"},{"v":0.662803524698305,"d":"0.66"},"up","no"]
["MSTRG.2857","AP002518.2","MSTRG.2857.1","NA","NA","NA","NA",null,{"v":3.276282,"d":"3.28"},{"v":1.245513,"d":"1.25"},{"v":2.63046792767318,"d":"2.63"},{"v":1.39531945993055,"d":"1.40"},{"v":0.110013842319861,"d":"0.11"},{"v":0.662948422876538,"d":"0.66"},"up","no"]
["ENSG00000267364","AC022706.1","ENST00000591886;ENST00000585387","NA","NA","NA","NA",null,{"v":1.82730129131653,"d":"1.83"},{"v":3.28323231792717,"d":"3.28"},{"v":0.556555587412765,"d":"0.56"},{"v":-0.845402307266715,"d":"-0.85"},{"v":0.11027131556427,"d":"0.11"},{"v":0.662948422876538,"d":"0.66"},"down","no"]
["ENSG00000166105","GLB1L3","ENST00000431683;ENST00000467068;ENST00000486034;ENST00000389887","GO:0016787(hydrolase activity);GO:0005975(carbohydrate metabolic process);GO:0008152(metabolic process);GO:0004553(hydrolase activity, hydrolyzing O-glycosyl compounds);GO:0016798(hydrolase activity, acting on glycosyl bonds);GO:0004565(beta-galactosidase activity);GO:0005773(vacuole);GO:0005773(vacuole)","NA","NA","NA","galactosidase beta 1 like 3 [Source:HGNC Symbol;Acc:HGNC:25147]",{"v":0.0856559713806596,"d":"0.09"},{"v":0.157465663610956,"d":"0.16"},{"v":0.543966026728762,"d":"0.54"},{"v":-0.878411543780232,"d":"-0.88"},{"v":0.110315502858018,"d":"0.11"},{"v":0.662948422876538,"d":"0.66"},"down","no"]
["MSTRG.8256","BBC3","ENST00000601438;ENST00000598636;ENST00000439096;ENST00000341983;ENST00000449228","GO:0005739(mitochondrion);GO:0006915(apoptotic process);GO:0043065(positive regulation of apoptotic process);GO:0005515(protein binding);GO:0005764(lysosome);GO:0051117(ATPase binding);GO:0090200(positive regulation of release of cytochrome c from mitochondria);GO:0097193(intrinsic apoptotic signaling pathway);GO:0005829(cytosol);GO:0005783(endoplasmic reticulum);GO:0001836(release of cytochrome c from mitochondria);GO:0032464(positive regulation of protein homooligomerization);GO:0042981(regulation of apoptotic process);GO:2001244(positive regulation of intrinsic apoptotic signaling pathway);GO:0005741(mitochondrial outer membrane);GO:0034976(response to endoplasmic reticulum stress);GO:0006919(activation of cysteine-type endopeptidase activity involved in apoptotic process);GO:0070059(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress);GO:2001056(positive regulation of cysteine-type endopeptidase activity);GO:0071456(cellular response to hypoxia);GO:0045926(negative regulation of growth);GO:1900740(positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway);GO:0097194(execution phase of apoptosis);GO:0001844(protein insertion into mitochondrial membrane involved in apoptotic signaling pathway);GO:1902237(positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway);GO:1903896(positive regulation of IRE1-mediated unfolded protein response);GO:0043525(positive regulation of neuron apoptotic process);GO:0051209(release of sequestered calcium ion into cytosol);GO:0006974(cellular response to DNA damage stimulus);GO:0008340(determination of adult lifespan);GO:0070245(positive regulation of thymocyte apoptotic process);GO:0032471(negative regulation of endoplasmic reticulum calcium ion concentration);GO:0032471(negative regulation of endoplasmic reticulum calcium ion concentration)","04390(Hippo signaling pathway);04210(Apoptosis);04215(Apoptosis - multiple species);04115(p53 signaling pathway);05200(Pathways in cancer);05210(Colorectal cancer);05016(Huntington's disease);05162(Measles);01524(Platinum drug resistance);01524(Platinum drug resistance)","K10132","NA","BCL2 binding component 3 [Source:HGNC Symbol;Acc:HGNC:17868]",{"v":3.89842288427673,"d":"3.90"},{"v":1.53685140660377,"d":"1.54"},{"v":2.53662967514323,"d":"2.54"},{"v":1.34291291442295,"d":"1.34"},{"v":0.11038154635462,"d":"0.11"},{"v":0.662948422876538,"d":"0.66"},"up","no"]
["MSTRG.6107","ZNF821","ENST00000561700;ENST00000569186;ENST00000611294;ENST00000562808;ENST00000562677;ENST00000568322;ENST00000446827;ENST00000313565;ENST00000562797;ENST00000565601;ENST00000566987;ENST00000568961;ENST00000425432;ENST00000565843;ENST00000568666","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0044212(transcription regulatory region DNA binding);GO:0044212(transcription regulatory region DNA binding)","NA","NA","NA","zinc finger protein 821 [Source:HGNC Symbol;Acc:HGNC:28043]",{"v":0.81016576925338,"d":"0.81"},{"v":1.42013922692534,"d":"1.42"},{"v":0.570483339867614,"d":"0.57"},{"v":-0.80974333955891,"d":"-0.81"},{"v":0.110432667934288,"d":"0.11"},{"v":0.662948422876538,"d":"0.66"},"down","no"]
["MSTRG.10089","SLC19A1","ENST00000311124;ENST00000485649;ENST00000567670;ENST00000486303;ENST00000417954;ENST00000460174;ENST00000427839;ENST00000468508;ENST00000380010;ENST00000443742;ENST00000528477","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0006810(transport);GO:0005887(integral component of plasma membrane);GO:0008517(folic acid transporter activity);GO:0015884(folic acid transport);GO:0015350(methotrexate transporter activity);GO:0051958(methotrexate transport);GO:0005886(plasma membrane);GO:0016324(apical plasma membrane);GO:0046655(folic acid metabolic process);GO:0005542(folic acid binding);GO:0016323(basolateral plasma membrane);GO:0008518(reduced folate carrier activity);GO:0098838(reduced folate transmembrane transport);GO:0098838(reduced folate transmembrane transport)","04977(Vitamin digestion and absorption);01523(Antifolate resistance);01523(Antifolate resistance)","K14609","NA","solute carrier family 19 member 1 [Source:HGNC Symbol;Acc:HGNC:10937]",{"v":5.28281924839607,"d":"5.28"},{"v":2.10465225534645,"d":"2.10"},{"v":2.51006751114162,"d":"2.51"},{"v":1.32772616763398,"d":"1.33"},{"v":0.110560979962298,"d":"0.11"},{"v":0.662948422876538,"d":"0.66"},"up","no"]
["MSTRG.2936","UBASH3B","ENST00000284273;ENST00000526493;ENST00000533451;ENST00000530578;ENST00000526386","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016787(hydrolase activity);GO:0004721(phosphoprotein phosphatase activity);GO:0005515(protein binding);GO:0004725(protein tyrosine phosphatase activity);GO:0042802(identical protein binding);GO:0031625(ubiquitin protein ligase binding);GO:0051219(phosphoprotein binding);GO:0006469(negative regulation of protein kinase activity);GO:0009968(negative regulation of signal transduction);GO:0030168(platelet activation);GO:0035335(peptidyl-tyrosine dephosphorylation);GO:0038063(collagen-activated tyrosine kinase receptor signaling pathway);GO:0038065(collagen-activated signaling pathway);GO:0043393(regulation of protein binding);GO:0045670(regulation of osteoclast differentiation);GO:0045671(negative regulation of osteoclast differentiation);GO:0045779(negative regulation of bone resorption);GO:0051279(regulation of release of sequestered calcium ion into cytosol);GO:0070527(platelet aggregation);GO:0090331(negative regulation of platelet aggregation);GO:0090331(negative regulation of platelet aggregation)","NA","NA","NA","ubiquitin associated and SH3 domain containing B [Source:HGNC Symbol;Acc:HGNC:29884]",{"v":3.6735494497836,"d":"3.67"},{"v":1.46376896237931,"d":"1.46"},{"v":2.50965114317792,"d":"2.51"},{"v":1.32748683469954,"d":"1.33"},{"v":0.110592158944891,"d":"0.11"},{"v":0.662948422876538,"d":"0.66"},"up","no"]
["ENSG00000052802","MSMO1","ENST00000261507;ENST00000504317;ENST00000505270;ENST00000507013;ENST00000393766","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0006629(lipid metabolic process);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0006694(steroid biosynthetic process);GO:0008202(steroid metabolic process);GO:0016126(sterol biosynthetic process);GO:0005506(iron ion binding);GO:0008610(lipid biosynthetic process);GO:0005886(plasma membrane);GO:0006695(cholesterol biosynthetic process);GO:0006631(fatty acid metabolic process);GO:0000254(C-4 methylsterol oxidase activity);GO:0000254(C-4 methylsterol oxidase activity)","00100(Steroid biosynthesis);00100(Steroid biosynthesis)","K07750","EC:1.14.18.9","methylsterol monooxygenase 1 [Source:HGNC Symbol;Acc:HGNC:10545]",{"v":2.14164852558783,"d":"2.14"},{"v":3.7203285764177,"d":"3.72"},{"v":0.575661122827495,"d":"0.58"},{"v":-0.796708311498428,"d":"-0.80"},{"v":0.110618377182082,"d":"0.11"},{"v":0.662948422876538,"d":"0.66"},"down","no"]
["ENSG00000173295","FAM86B3P","ENST00000522601;ENST00000590591;ENST00000310542;ENST00000588728","NA","NA","NA","NA","family with sequence similarity 86 member B3, pseudogene [Source:HGNC Symbol;Acc:HGNC:44371]",{"v":0.509515879671458,"d":"0.51"},{"v":0.191280920533881,"d":"0.19"},{"v":2.66370466144431,"d":"2.66"},{"v":1.41343413230038,"d":"1.41"},{"v":0.110640137389596,"d":"0.11"},{"v":0.662948422876538,"d":"0.66"},"up","no"]
["MSTRG.1263","TPR","ENST00000367478;ENST00000474852;ENST00000492973;ENST00000469463;ENST00000481347;ENST00000467810;ENST00000491783;ENST00000451586;ENST00000613151","GO:0003723(RNA binding);GO:0006810(transport);GO:0051028(mRNA transport);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0015031(protein transport);GO:0031965(nuclear membrane);GO:0051301(cell division);GO:0005694(chromosome);GO:0042803(protein homodimerization activity);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0007049(cell cycle);GO:0005643(nuclear pore);GO:0005819(spindle);GO:0000775(chromosome, centromeric region);GO:0000776(kinetochore);GO:0003729(mRNA binding);GO:0005868(cytoplasmic dynein complex);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0003674(molecular_function);GO:0008150(biological_process);GO:0005575(cellular_component);GO:0005654(nucleoplasm);GO:0075733(intracellular transport of virus);GO:0043657(host cell);GO:0003682(chromatin binding);GO:0070840(dynein complex binding);GO:0042307(positive regulation of protein import into nucleus);GO:0019898(extrinsic component of membrane);GO:0015631(tubulin binding);GO:0005635(nuclear envelope);GO:0090267(positive regulation of mitotic cell cycle spindle assembly checkpoint);GO:0090316(positive regulation of intracellular protein transport);GO:0016032(viral process);GO:0006406(mRNA export from nucleus);GO:0051019(mitogen-activated protein kinase binding);GO:0016925(protein sumoylation);GO:0060964(regulation of gene silencing by miRNA);GO:0006110(regulation of glycolytic process);GO:0006409(tRNA export from nucleus);GO:0007077(mitotic nuclear envelope disassembly);GO:0019083(viral transcription);GO:1900034(regulation of cellular response to heat);GO:0034605(cellular response to heat);GO:1901673(regulation of mitotic spindle assembly);GO:0007094(mitotic spindle assembly checkpoint);GO:0006606(protein import into nucleus);GO:0045947(negative regulation of translational initiation);GO:0042405(nuclear inclusion body);GO:0072686(mitotic spindle);GO:0031072(heat shock protein binding);GO:0046827(positive regulation of protein export from nucleus);GO:0034399(nuclear periphery);GO:0005487(nucleocytoplasmic transporter activity);GO:0000189(MAPK import into nucleus);GO:0006404(RNA import into nucleus);GO:0006405(RNA export from nucleus);GO:0006999(nuclear pore organization);GO:0010965(regulation of mitotic sister chromatid separation);GO:0031453(positive regulation of heterochromatin assembly);GO:0031990(mRNA export from nucleus in response to heat stress);GO:0035457(cellular response to interferon-alpha);GO:0046832(negative regulation of RNA export from nucleus);GO:0070849(response to epidermal growth factor);GO:0044615(nuclear pore nuclear basket);GO:0044615(nuclear pore nuclear basket)","03013(RNA transport);05200(Pathways in cancer);05216(Thyroid cancer);05216(Thyroid cancer)","K09291","NA","translocated promoter region, nuclear basket protein [Source:HGNC Symbol;Acc:HGNC:12017]",{"v":14.1229426289879,"d":"14.12"},{"v":5.64309939773279,"d":"5.64"},{"v":2.50269251586496,"d":"2.50"},{"v":1.32348105048023,"d":"1.32"},{"v":0.110755710694972,"d":"0.11"},{"v":0.662948422876538,"d":"0.66"},"up","no"]
["MSTRG.1858","ACTA2","ENST00000224784;ENST00000415557;ENST00000482085;ENST00000458159;ENST00000480297;ENST00000488967","GO:0005737(cytoplasm);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0005856(cytoskeleton);GO:0005615(extracellular space);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0009615(response to virus);GO:0043234(protein complex);GO:0010628(positive regulation of gene expression);GO:0019901(protein kinase binding);GO:0008217(regulation of blood pressure);GO:0014829(vascular smooth muscle contraction);GO:0090131(mesenchyme migration);GO:0015629(actin cytoskeleton);GO:0030027(lamellipodium);GO:0030175(filopodium);GO:0030485(smooth muscle contractile fiber);GO:0044297(cell body);GO:0006936(muscle contraction);GO:0072144(glomerular mesangial cell development);GO:0072144(glomerular mesangial cell development)","04371(Apelin signaling pathway);04926(Relaxin signaling pathway);04270(Vascular smooth muscle contraction);04270(Vascular smooth muscle contraction)","K12313","NA","actin, alpha 2, smooth muscle, aorta [Source:HGNC Symbol;Acc:HGNC:130]",{"v":1.61654038575269,"d":"1.62"},{"v":0.630684373319892,"d":"0.63"},{"v":2.56315274983475,"d":"2.56"},{"v":1.35791945789695,"d":"1.36"},{"v":0.11076303504367,"d":"0.11"},{"v":0.662948422876538,"d":"0.66"},"up","no"]
["MSTRG.7199","NT5C","ENST00000245552;ENST00000584352;ENST00000579023;ENST00000580758;ENST00000578095;ENST00000578337;ENST00000582170;ENST00000577523;ENST00000580423;ENST00000583655;ENST00000582744;ENST00000579082;ENST00000582160","GO:0016311(dephosphorylation);GO:0008253(5'-nucleotidase activity);GO:0009264(deoxyribonucleotide catabolic process);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0005829(cytosol);GO:0016787(hydrolase activity);GO:0009117(nucleotide metabolic process);GO:0070062(extracellular exosome);GO:0006195(purine nucleotide catabolic process);GO:0046135(pyrimidine nucleoside catabolic process);GO:0008252(nucleotidase activity);GO:0019103(pyrimidine nucleotide binding);GO:0009223(pyrimidine deoxyribonucleotide catabolic process);GO:0016791(phosphatase activity);GO:0005739(mitochondrion);GO:0005739(mitochondrion)","00230(Purine metabolism);00240(Pyrimidine metabolism);00760(Nicotinate and nicotinamide metabolism);00760(Nicotinate and nicotinamide metabolism)","K01081","EC:3.1.3.5","5', 3'-nucleotidase, cytosolic [Source:HGNC Symbol;Acc:HGNC:17144]",{"v":4.44731297899427,"d":"4.45"},{"v":7.70936613239975,"d":"7.71"},{"v":0.576871418819218,"d":"0.58"},{"v":-0.793678308259467,"d":"-0.79"},{"v":0.11083024394286,"d":"0.11"},{"v":0.662948422876538,"d":"0.66"},"down","no"]
["MSTRG.6962","SKAP1","ENST00000336915;ENST00000583844;ENST00000581419;ENST00000579476;ENST00000579336;MSTRG.6962.1;ENST00000581400;ENST00000584924;ENST00000584709","GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0009967(positive regulation of signal transduction);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0045893(positive regulation of transcription, DNA-templated);GO:0002376(immune system process);GO:0002250(adaptive immune response);GO:0019901(protein kinase binding);GO:0042169(SH2 domain binding);GO:0019903(protein phosphatase binding);GO:0050852(T cell receptor signaling pathway);GO:0017124(SH3 domain binding);GO:0005070(SH3/SH2 adaptor activity);GO:0032403(protein complex binding);GO:0045785(positive regulation of cell adhesion);GO:0072659(protein localization to plasma membrane);GO:0005829(cytosol);GO:0005911(cell-cell junction);GO:0042101(T cell receptor complex);GO:0042101(T cell receptor complex)","04015(Rap1 signaling pathway);04015(Rap1 signaling pathway)","K17699","NA","src kinase associated phosphoprotein 1 [Source:HGNC Symbol;Acc:HGNC:15605]",{"v":10.8627104615094,"d":"10.86"},{"v":18.7226052928302,"d":"18.72"},{"v":0.580192248440406,"d":"0.58"},{"v":-0.785397074103762,"d":"-0.79"},{"v":0.110846741226546,"d":"0.11"},{"v":0.662948422876538,"d":"0.66"},"down","no"]
["MSTRG.1742","RUFY2","ENST00000602465;ENST00000491118;ENST00000265865;ENST00000473398;ENST00000388768;ENST00000399200;ENST00000466187;ENST00000466493;ENST00000342616","GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0046872(metal ion binding)","NA","NA","NA","RUN and FYVE domain containing 2 [Source:HGNC Symbol;Acc:HGNC:19761]",{"v":0.740095084552046,"d":"0.74"},{"v":0.286835936094384,"d":"0.29"},{"v":2.58020349412744,"d":"2.58"},{"v":1.36748485184669,"d":"1.37"},{"v":0.110855932166301,"d":"0.11"},{"v":0.662948422876538,"d":"0.66"},"up","no"]
["ENSG00000223959","AFG3L1P","ENST00000427658;ENST00000421164;ENST00000355531;ENST00000557444;ENST00000431757;ENST00000450026;ENST00000429663;ENST00000436447;ENST00000423684;ENST00000437774;ENST00000418696","NA","NA","NA","NA","AFG3 like matrix AAA peptidase subunit 1, pseudogene [Source:HGNC Symbol;Acc:HGNC:314]",{"v":0.632705963071758,"d":"0.63"},{"v":0.245344250944188,"d":"0.25"},{"v":2.57884976165873,"d":"2.58"},{"v":1.36672772720878,"d":"1.37"},{"v":0.110855932166301,"d":"0.11"},{"v":0.662948422876538,"d":"0.66"},"up","no"]
["ENSG00000165115","KIF27","ENST00000297814;ENST00000413982;ENST00000376347;ENST00000495062","GO:0005737(cytoplasm);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0003777(microtubule motor activity);GO:0005856(cytoskeleton);GO:0042995(cell projection);GO:0008017(microtubule binding);GO:0005874(microtubule);GO:0007018(microtubule-based movement);GO:0060271(cilium assembly);GO:0005929(cilium);GO:0070062(extracellular exosome);GO:0030030(cell projection organization);GO:0005871(kinesin complex);GO:0008574(ATP-dependent microtubule motor activity, plus-end-directed);GO:0003774(motor activity);GO:0003774(motor activity)","NA","NA","NA","kinesin family member 27 [Source:HGNC Symbol;Acc:HGNC:18632]",{"v":1.5646493,"d":"1.56"},{"v":0.613761177042801,"d":"0.61"},{"v":2.549280336594,"d":"2.55"},{"v":1.35009003086329,"d":"1.35"},{"v":0.110923058451472,"d":"0.11"},{"v":0.662948422876538,"d":"0.66"},"up","no"]
["MSTRG.600","USP24","ENST00000294383;ENST00000482197;ENST00000480962;ENST00000472566;ENST00000512504;ENST00000634589;ENST00000484447","GO:0016579(protein deubiquitination);GO:0016787(hydrolase activity);GO:0008233(peptidase activity);GO:0008234(cysteine-type peptidase activity);GO:0006508(proteolysis);GO:0006511(ubiquitin-dependent protein catabolic process);GO:0036459(thiol-dependent ubiquitinyl hydrolase activity);GO:0005654(nucleoplasm);GO:0005654(nucleoplasm)","NA","NA","NA","ubiquitin specific peptidase 24 [Source:HGNC Symbol;Acc:HGNC:12623]",{"v":8.55795413311247,"d":"8.56"},{"v":3.41738645948012,"d":"3.42"},{"v":2.50423949254319,"d":"2.50"},{"v":1.32437254077782,"d":"1.32"},{"v":0.110940744844611,"d":"0.11"},{"v":0.662948422876538,"d":"0.66"},"up","no"]
["ENSG00000036448","MYOM2","ENST00000262113;ENST00000520072;ENST00000612167;ENST00000520298;ENST00000520779;ENST00000519631;ENST00000518513","GO:0005737(cytoplasm);GO:0005739(mitochondrion);GO:0005515(protein binding);GO:0051015(actin filament binding);GO:0051371(muscle alpha-actinin binding);GO:0097493(structural molecule activity conferring elasticity);GO:0006941(striated muscle contraction);GO:0007015(actin filament organization);GO:0045214(sarcomere organization);GO:0071688(striated muscle myosin thick filament assembly);GO:0005859(muscle myosin complex);GO:0030018(Z disc);GO:0031430(M band);GO:0032982(myosin filament);GO:0006936(muscle contraction);GO:0008307(structural constituent of muscle);GO:0019900(kinase binding);GO:0002074(extraocular skeletal muscle development);GO:0002074(extraocular skeletal muscle development)","NA","NA","NA","myomesin 2 [Source:HGNC Symbol;Acc:HGNC:7614]",{"v":0.37823432979326,"d":"0.38"},{"v":0.665241125177004,"d":"0.67"},{"v":0.568567269037406,"d":"0.57"},{"v":-0.814597045742803,"d":"-0.81"},{"v":0.110976641184189,"d":"0.11"},{"v":0.662948422876538,"d":"0.66"},"down","no"]
["ENSG00000102554","KLF5","ENST00000377687;ENST00000464404;ENST00000477333","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0005794(Golgi apparatus);GO:0043231(intracellular membrane-bounded organelle);GO:0046872(metal ion binding);GO:0005654(nucleoplasm);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0006366(transcription from RNA polymerase II promoter);GO:0001077(transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0008134(transcription factor binding);GO:0043565(sequence-specific DNA binding);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0001525(angiogenesis);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0008284(positive regulation of cell proliferation);GO:0030033(microvillus assembly);GO:0032534(regulation of microvillus assembly);GO:0035914(skeletal muscle cell differentiation);GO:0045600(positive regulation of fat cell differentiation);GO:0045893(positive regulation of transcription, DNA-templated);GO:0060576(intestinal epithelial cell development);GO:0071407(cellular response to organic cyclic compound);GO:1901653(cellular response to peptide);GO:1990830(cellular response to leukemia inhibitory factor);GO:1990830(cellular response to leukemia inhibitory factor)","NA","NA","NA","Kruppel like factor 5 [Source:HGNC Symbol;Acc:HGNC:6349]",{"v":0.863833958900591,"d":"0.86"},{"v":0.332183937837144,"d":"0.33"},{"v":2.60046877800604,"d":"2.60"},{"v":1.37877171661657,"d":"1.38"},{"v":0.111067023901443,"d":"0.11"},{"v":0.663147222913858,"d":"0.66"},"up","no"]
["ENSG00000227372","TP73-AS1","ENST00000452079;ENST00000624167;ENST00000418088;ENST00000423764;ENST00000624948;ENST00000636630;ENST00000419973;ENST00000608600;ENST00000587071","NA","NA","NA","NA","TP73 antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:29052]",{"v":0.911122434456929,"d":"0.91"},{"v":0.35721273921487,"d":"0.36"},{"v":2.55064373252621,"d":"2.55"},{"v":1.35086140101327,"d":"1.35"},{"v":0.111208594321064,"d":"0.11"},{"v":0.663394406433772,"d":"0.66"},"up","no"]
["MSTRG.15171","TLR8","MSTRG.15171.2;ENST00000218032;ENST00000311912","GO:0003723(RNA binding);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0003677(DNA binding);GO:0007165(signal transduction);GO:0003727(single-stranded RNA binding);GO:0006954(inflammatory response);GO:0003725(double-stranded RNA binding);GO:0051607(defense response to virus);GO:0002376(immune system process);GO:0002755(MyD88-dependent toll-like receptor signaling pathway);GO:0045087(innate immune response);GO:0050707(regulation of cytokine secretion);GO:0005887(integral component of plasma membrane);GO:0005789(endoplasmic reticulum membrane);GO:0010008(endosome membrane);GO:0004872(receptor activity);GO:0009615(response to virus);GO:0045089(positive regulation of innate immune response);GO:0002224(toll-like receptor signaling pathway);GO:0045416(positive regulation of interleukin-8 biosynthetic process);GO:0071260(cellular response to mechanical stimulus);GO:0000139(Golgi membrane);GO:0007249(I-kappaB kinase/NF-kappaB signaling);GO:0045078(positive regulation of interferon-gamma biosynthetic process);GO:0045356(positive regulation of interferon-alpha biosynthetic process);GO:0045359(positive regulation of interferon-beta biosynthetic process);GO:0036020(endolysosome membrane);GO:0034162(toll-like receptor 9 signaling pathway);GO:2000778(positive regulation of interleukin-6 secretion);GO:0016064(immunoglobulin mediated immune response);GO:0009897(external side of plasma membrane);GO:0034158(toll-like receptor 8 signaling pathway);GO:0050718(positive regulation of interleukin-1 beta secretion);GO:2001183(negative regulation of interleukin-12 secretion);GO:0008144(drug binding);GO:0001774(microglial cell activation);GO:0001932(regulation of protein phosphorylation);GO:0001932(regulation of protein phosphorylation)","04620(Toll-like receptor signaling pathway);04620(Toll-like receptor signaling pathway)","K10170","NA","toll like receptor 8 [Source:HGNC Symbol;Acc:HGNC:15632]",{"v":4.29807499428281,"d":"4.30"},{"v":1.71340754275187,"d":"1.71"},{"v":2.50849543207902,"d":"2.51"},{"v":1.32682231098523,"d":"1.33"},{"v":0.111248578729797,"d":"0.11"},{"v":0.663394406433772,"d":"0.66"},"up","no"]
["MSTRG.5789","BOLA2;BOLA2-SMG1P6;SMG1P6","ENST00000330978;ENST00000568556;ENST00000569622;ENST00000532337;ENST00000565417","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005515(protein binding);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0035722(interleukin-12-mediated signaling pathway);GO:0044571([2Fe-2S] cluster assembly);GO:0097428(protein maturation by iron-sulfur cluster transfer)","NA","NA","NA","bolA family member 2 [Source:HGNC Symbol;Acc:HGNC:29488];BOLA2-SMG1P6 readthrough [Source:HGNC Symbol;Acc:HGNC:53563];SMG1P6, nonsense mediated mRNA decay associated PI3K related kinasepseudogene 6 [Source:HGNC Symbol;Acc:HGNC:49863]",{"v":0.843726795101649,"d":"0.84"},{"v":1.46095816327837,"d":"1.46"},{"v":0.577516055085614,"d":"0.58"},{"v":-0.792067040531081,"d":"-0.79"},{"v":0.111279798823128,"d":"0.11"},{"v":0.663394406433772,"d":"0.66"},"down","no"]
["MSTRG.6767","RPL23","ENST00000479035;ENST00000245857;ENST00000584056;ENST00000394333;ENST00000584583;ENST00000577407;ENST00000470646;ENST00000584912;ENST00000394332;ENST00000577760","GO:0003723(RNA binding);GO:0016020(membrane);GO:0006412(translation);GO:0030529(intracellular ribonucleoprotein complex);GO:0003735(structural constituent of ribosome);GO:0005840(ribosome);GO:0005515(protein binding);GO:0005925(focal adhesion);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0031012(extracellular matrix);GO:0043234(protein complex);GO:0006413(translational initiation);GO:0006610(ribosomal protein import into nucleus);GO:0006364(rRNA processing);GO:0005737(cytoplasm);GO:0000184(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay);GO:0019083(viral transcription);GO:0006614(SRP-dependent cotranslational protein targeting to membrane);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0008284(positive regulation of cell proliferation);GO:0010628(positive regulation of gene expression);GO:0032986(protein-DNA complex disassembly);GO:0050821(protein stabilization);GO:0005654(nucleoplasm);GO:0071158(positive regulation of cell cycle arrest);GO:0072717(cellular response to actinomycin D);GO:0022625(cytosolic large ribosomal subunit);GO:0005730(nucleolus);GO:0031625(ubiquitin protein ligase binding);GO:0001223(transcription coactivator binding);GO:1990948(ubiquitin ligase inhibitor activity);GO:1904667(negative regulation of ubiquitin protein ligase activity);GO:2000059(negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process);GO:0070180(large ribosomal subunit rRNA binding);GO:0071157(negative regulation of cell cycle arrest);GO:1901798(positive regulation of signal transduction by p53 class mediator);GO:1901798(positive regulation of signal transduction by p53 class mediator)","03010(Ribosome);03010(Ribosome)","K02894","NA","ribosomal protein L23 [Source:HGNC Symbol;Acc:HGNC:10316]",{"v":36.5193655318615,"d":"36.52"},{"v":62.7767790416458,"d":"62.78"},{"v":0.581733661544418,"d":"0.58"},{"v":-0.781569307932891,"d":"-0.78"},{"v":0.111613204440912,"d":"0.11"},{"v":0.66435003808063,"d":"0.66"},"down","no"]
["MSTRG.2823","KBTBD3","ENST00000531837;ENST00000528483;ENST00000526805;ENST00000534815;ENST00000526793;ENST00000531482","GO:0016567(protein ubiquitination);GO:0004842(ubiquitin-protein transferase activity);GO:0031463(Cul3-RING ubiquitin ligase complex);GO:0031463(Cul3-RING ubiquitin ligase complex)","NA","NA","NA","kelch repeat and BTB domain containing 3 [Source:HGNC Symbol;Acc:HGNC:22934]",{"v":0.291945431472081,"d":"0.29"},{"v":0.514419417693981,"d":"0.51"},{"v":0.567524128037006,"d":"0.57"},{"v":-0.817246365639102,"d":"-0.82"},{"v":0.111639193280153,"d":"0.11"},{"v":0.66435003808063,"d":"0.66"},"down","no"]
["ENSG00000248405","PRR5-ARHGAP8","ENST00000361473;ENST00000495250;ENST00000352766","GO:0007165(signal transduction);GO:0005737(cytoplasm);GO:0043087(regulation of GTPase activity);GO:0043087(regulation of GTPase activity)","NA","NA","NA","PRR5-ARHGAP8 readthrough [Source:HGNC Symbol;Acc:HGNC:34512]",{"v":0.256975295036765,"d":"0.26"},{"v":0.470156995404412,"d":"0.47"},{"v":0.546573373465866,"d":"0.55"},{"v":-0.87151291476355,"d":"-0.87"},{"v":0.111715843628473,"d":"0.11"},{"v":0.66435003808063,"d":"0.66"},"down","no"]
["ENSG00000105556","MIER2","ENST00000264819;ENST00000586994;ENST00000635755;ENST00000621180;ENST00000592722","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0004407(histone deacetylase activity);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0043234(protein complex);GO:0042826(histone deacetylase binding);GO:0016575(histone deacetylation);GO:0016575(histone deacetylation)","NA","NA","NA","MIER family member 2 [Source:HGNC Symbol;Acc:HGNC:29210]",{"v":0.80110942990301,"d":"0.80"},{"v":0.313417819120796,"d":"0.31"},{"v":2.55604302317684,"d":"2.56"},{"v":1.35391211985356,"d":"1.35"},{"v":0.111724274109152,"d":"0.11"},{"v":0.66435003808063,"d":"0.66"},"up","no"]
["ENSG00000142867","BCL10","ENST00000370580;ENST00000620248","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0042981(regulation of apoptotic process);GO:0005829(cytosol);GO:0006915(apoptotic process);GO:0005515(protein binding);GO:0048471(perinuclear region of cytoplasm);GO:0045121(membrane raft);GO:0051092(positive regulation of NF-kappaB transcription factor activity);GO:0003713(transcription coactivator activity);GO:0045893(positive regulation of transcription, DNA-templated);GO:0002376(immune system process);GO:0045087(innate immune response);GO:0005764(lysosome);GO:0002250(adaptive immune response);GO:0038095(Fc-epsilon receptor signaling pathway);GO:0005886(plasma membrane);GO:0042802(identical protein binding);GO:0016567(protein ubiquitination);GO:0019901(protein kinase binding);GO:0002223(stimulatory C-type lectin receptor signaling pathway);GO:0050852(T cell receptor signaling pathway);GO:0043234(protein complex);GO:0043065(positive regulation of apoptotic process);GO:0031625(ubiquitin protein ligase binding);GO:0031398(positive regulation of protein ubiquitination);GO:0008022(protein C-terminus binding);GO:0043123(positive regulation of I-kappaB kinase/NF-kappaB signaling);GO:0019899(enzyme binding);GO:0045416(positive regulation of interleukin-8 biosynthetic process);GO:0071260(cellular response to mechanical stimulus);GO:0046696(lipopolysaccharide receptor complex);GO:0008134(transcription factor binding);GO:0051259(protein oligomerization);GO:0008219(cell death);GO:0043621(protein self-association);GO:0042327(positive regulation of phosphorylation);GO:0001843(neural tube closure);GO:0005881(cytoplasmic microtubule);GO:0051059(NF-kappaB binding);GO:0019900(kinase binding);GO:0051260(protein homooligomerization);GO:2001238(positive regulation of extrinsic apoptotic signaling pathway);GO:0002020(protease binding);GO:0042101(T cell receptor complex);GO:0019209(kinase activator activity);GO:0043422(protein kinase B binding);GO:0001783(B cell apoptotic process);GO:0002224(toll-like receptor signaling pathway);GO:0002237(response to molecule of bacterial origin);GO:0002906(negative regulation of mature B cell apoptotic process);GO:0006968(cellular defense response);GO:0007249(I-kappaB kinase/NF-kappaB signaling);GO:0009620(response to fungus);GO:0016064(immunoglobulin mediated immune response);GO:0032094(response to food);GO:0032765(positive regulation of mast cell cytokine production);GO:0042109(lymphotoxin A biosynthetic process);GO:0042226(interleukin-6 biosynthetic process);GO:0043280(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process);GO:0050856(regulation of T cell receptor signaling pathway);GO:0050870(positive regulation of T cell activation);GO:0051291(protein heterooligomerization);GO:0070231(T cell apoptotic process);GO:0001772(immunological synapse);GO:0032449(CBM complex);GO:0032449(CBM complex)","04064(NF-kappa B signaling pathway);04660(T cell receptor signaling pathway);04662(B cell receptor signaling pathway);05152(Tuberculosis);05152(Tuberculosis)","K07368","NA","B-cell CLL/lymphoma 10 [Source:HGNC Symbol;Acc:HGNC:989]",{"v":3.1524956484569,"d":"3.15"},{"v":1.24569550124157,"d":"1.25"},{"v":2.53071127359362,"d":"2.53"},{"v":1.33954292115254,"d":"1.34"},{"v":0.111801250256487,"d":"0.11"},{"v":0.66435003808063,"d":"0.66"},"up","no"]
["MSTRG.7893","PRKACA","ENST00000308677;ENST00000590853;ENST00000589994;ENST00000593092;ENST00000589284;ENST00000587372;ENST00000587533;ENST00000536649;ENST00000350356;ENST00000588209","GO:0010881(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion);GO:0002027(regulation of heart rate);GO:0006397(mRNA processing);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016607(nuclear speck);GO:0016020(membrane);GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0005829(cytosol);GO:0016740(transferase activity);GO:0031514(motile cilium);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0045171(intercellular bridge);GO:0005739(mitochondrion);GO:0005886(plasma membrane);GO:0042995(cell projection);GO:0005515(protein binding);GO:0048471(perinuclear region of cytoplasm);GO:0031410(cytoplasmic vesicle);GO:0000287(magnesium ion binding);GO:0004691(cAMP-dependent protein kinase activity);GO:0019904(protein domain specific binding);GO:0030145(manganese ion binding);GO:0034237(protein kinase A regulatory subunit binding);GO:0001707(mesoderm formation);GO:0001843(neural tube closure);GO:0018105(peptidyl-serine phosphorylation);GO:0018107(peptidyl-threonine phosphorylation);GO:0046777(protein autophosphorylation);GO:0046827(positive regulation of protein export from nucleus);GO:0048240(sperm capacitation);GO:0050804(modulation of synaptic transmission);GO:0070613(regulation of protein processing);GO:0071158(positive regulation of cell cycle arrest);GO:0071374(cellular response to parathyroid hormone stimulus);GO:1901621(negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning);GO:0001669(acrosomal vesicle);GO:0005952(cAMP-dependent protein kinase complex);GO:0031594(neuromuscular junction);GO:0036126(sperm flagellum);GO:0043197(dendritic spine);GO:0097546(ciliary base);GO:0005813(centrosome);GO:0005929(cilium);GO:0005654(nucleoplasm);GO:0070062(extracellular exosome);GO:0019901(protein kinase binding);GO:0002223(stimulatory C-type lectin receptor signaling pathway);GO:0031625(ubiquitin protein ligase binding);GO:0000086(G2/M transition of mitotic cell cycle);GO:0010389(regulation of G2/M transition of mitotic cell cycle);GO:0097711(ciliary basal body docking);GO:0004712(protein serine/threonine/tyrosine kinase activity);GO:2000810(regulation of bicellular tight junction assembly);GO:1903779(regulation of cardiac conduction);GO:0061136(regulation of proteasomal protein catabolic process);GO:0034704(calcium channel complex);GO:0055117(regulation of cardiac muscle contraction);GO:0007596(blood coagulation);GO:0016241(regulation of macroautophagy);GO:0003091(renal water homeostasis);GO:0034199(activation of protein kinase A activity);GO:0071377(cellular response to glucagon stimulus);GO:0034605(cellular response to heat);GO:0034380(high-density lipoprotein particle assembly);GO:0051480(regulation of cytosolic calcium ion concentration);GO:0044853(plasma membrane raft);GO:0086064(cell communication by electrical coupling involved in cardiac conduction);GO:0060314(regulation of ryanodine-sensitive calcium-release channel activity);GO:0035584(calcium-mediated signaling using intracellular calcium source);GO:0043393(regulation of protein binding);GO:0045667(regulation of osteoblast differentiation);GO:0071333(cellular response to glucose stimulus);GO:0071872(cellular response to epinephrine stimulus);GO:0071872(cellular response to epinephrine stimulus)","04014(Ras signaling pathway);04010(MAPK signaling pathway);04310(Wnt signaling pathway);04340(Hedgehog signaling pathway);04371(Apelin signaling pathway);04020(Calcium signaling pathway);04024(cAMP signaling pathway);04140(Autophagy - animal);04114(Oocyte meiosis);04530(Tight junction);04540(Gap junction);04611(Platelet activation);04062(Chemokine signaling pathway);04911(Insulin secretion);04910(Insulin signaling pathway);04922(Glucagon signaling pathway);04923(Regulation of lipolysis in adipocyte);04912(GnRH signaling pathway);04913(Ovarian Steroidogenesis);04915(Estrogen signaling pathway);04914(Progesterone-mediated oocyte maturation);04921(Oxytocin signaling pathway);04926(Relaxin signaling pathway);04918(Thyroid hormone synthesis);04919(Thyroid hormone signaling pathway);04916(Melanogenesis);04924(Renin secretion);04925(Aldosterone synthesis and secretion);04927(Cortisol synthesis and secretion);04261(Adrenergic signaling in cardiomyocytes);04270(Vascular smooth muscle contraction);04970(Salivary secretion);04971(Gastric acid secretion);04976(Bile secretion);04962(Vasopressin-regulated water reabsorption);04961(Endocrine and other factor-regulated calcium reabsorption);04724(Glutamatergic synapse);04727(GABAergic synapse);04725(Cholinergic synapse);04728(Dopaminergic synapse);04726(Serotonergic synapse);04720(Long-term potentiation);04723(Retrograde endocannabinoid signaling);04740(Olfactory transduction);04742(Taste transduction);04750(Inflammatory mediator regulation of TRP channels);04211(Longevity regulating pathway - mammal);04213(Longevity regulating pathway - multiple species);04713(Circadian entrainment);05200(Pathways in cancer);05205(Proteoglycans in cancer);05203(Viral carcinogenesis);05012(Parkinson's disease);05020(Prion diseases);05030(Cocaine addiction);05031(Amphetamine addiction);05032(Morphine addiction);05034(Alcoholism);05414(Dilated cardiomyopathy (DCM));05110(Vibrio cholerae infection);05166(HTLV-I infection);05169(Epstein-Barr virus infection);05165(Human papillomavirus infection);05146(Amoebiasis);01522(Endocrine resistance);01522(Endocrine resistance)","K04345","EC:2.7.11.11","protein kinase cAMP-activated catalytic subunit alpha [Source:HGNC Symbol;Acc:HGNC:9380]",{"v":11.8498962849935,"d":"11.85"},{"v":4.74100634716797,"d":"4.74"},{"v":2.49944746268311,"d":"2.50"},{"v":1.32160920250728,"d":"1.32"},{"v":0.111908364392889,"d":"0.11"},{"v":0.66435003808063,"d":"0.66"},"up","no"]
["ENSG00000204406","MBD5","ENST00000407073;ENST00000404807;ENST00000488372;ENST00000635796;ENST00000496158;ENST00000473478;ENST00000636948;ENST00000637830;ENST00000637997;ENST00000629878;ENST00000628572;ENST00000637316;ENST00000478804;ENST00000637308;ENST00000636371;ENST00000469438;ENST00000638090;ENST00000478190;ENST00000637242;ENST00000636620;ENST00000496893;ENST00000627651","GO:0005634(nucleus);GO:0005694(chromosome);GO:0030496(midbody);GO:0007399(nervous system development);GO:0005654(nucleoplasm);GO:0070062(extracellular exosome);GO:0016579(protein deubiquitination);GO:0003682(chromatin binding);GO:0042593(glucose homeostasis);GO:0040014(regulation of multicellular organism growth);GO:0010369(chromocenter);GO:0044708(single-organism behavior);GO:0060399(positive regulation of growth hormone receptor signaling pathway);GO:0003677(DNA binding);GO:0003677(DNA binding)","NA","NA","NA","methyl-CpG binding domain protein 5 [Source:HGNC Symbol;Acc:HGNC:20444]",{"v":0.539574384647098,"d":"0.54"},{"v":0.214243120011544,"d":"0.21"},{"v":2.51851440838812,"d":"2.52"},{"v":1.33257298465924,"d":"1.33"},{"v":0.111991589506945,"d":"0.11"},{"v":0.66435003808063,"d":"0.66"},"up","no"]
["ENSG00000160193","WDR4","ENST00000492742;ENST00000476326;ENST00000330317;ENST00000479429;ENST00000398208","GO:0005634(nucleus);GO:0005829(cytosol);GO:0008033(tRNA processing);GO:0005515(protein binding);GO:0005654(nucleoplasm);GO:0106004(tRNA (guanine-N7)-methylation);GO:0008176(tRNA (guanine-N7-)-methyltransferase activity);GO:0006400(tRNA modification);GO:0036265(RNA (guanine-N7)-methylation);GO:0043527(tRNA methyltransferase complex);GO:0043527(tRNA methyltransferase complex)","NA","NA","NA","WD repeat domain 4 [Source:HGNC Symbol;Acc:HGNC:12756]",{"v":1.29047050913075,"d":"1.29"},{"v":0.498718072315559,"d":"0.50"},{"v":2.58757518679655,"d":"2.59"},{"v":1.37160078340137,"d":"1.37"},{"v":0.112045616492236,"d":"0.11"},{"v":0.66435003808063,"d":"0.66"},"up","no"]
["MSTRG.12907","HLA-DQA1;HLA-DQA2","ENST00000343139;MSTRG.12907.1;ENST00000395363;ENST00000374949;ENST00000374940;ENST00000460633;ENST00000482745","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005794(Golgi apparatus);GO:0005765(lysosomal membrane);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005886(plasma membrane);GO:0006955(immune response);GO:0002376(immune system process);GO:0005764(lysosome);GO:0005887(integral component of plasma membrane);GO:0002504(antigen processing and presentation of peptide or polysaccharide antigen via MHC class II);GO:0019882(antigen processing and presentation);GO:0042613(MHC class II protein complex);GO:0005768(endosome);GO:0050852(T cell receptor signaling pathway);GO:0010008(endosome membrane);GO:0019886(antigen processing and presentation of exogenous peptide antigen via MHC class II);GO:0032588(trans-Golgi network membrane);GO:0000139(Golgi membrane);GO:0030666(endocytic vesicle membrane);GO:0060333(interferon-gamma-mediated signaling pathway);GO:0012507(ER to Golgi transport vesicle membrane);GO:0031295(T cell costimulation);GO:0042605(peptide antigen binding);GO:0071556(integral component of lumenal side of endoplasmic reticulum membrane);GO:0030669(clathrin-coated endocytic vesicle membrane);GO:0030658(transport vesicle membrane);GO:0032395(MHC class II receptor activity);GO:0046872(metal ion binding);GO:0046872(metal ion binding)","04514(Cell adhesion molecules (CAMs));04145(Phagosome);04640(Hematopoietic cell lineage);04612(Antigen processing and presentation);04658(Th1 and Th2 cell differentiation);04659(Th17 cell differentiation);04672(Intestinal immune network for IgA production);05310(Asthma);05322(Systemic lupus erythematosus);05323(Rheumatoid arthritis);05320(Autoimmune thyroid disease);05321(Inflammatiory bowel disease (IBD));05330(Allograft rejection);05332(Graft-versus-host disease);05416(Viral myocarditis);04940(Type I diabetes mellitus);05150(Staphylococcus aureus infection);05152(Tuberculosis);05166(HTLV-I infection);05164(Influenza A);05168(Herpes simplex infection);05169(Epstein-Barr virus infection);05145(Toxoplasmosis);05140(Leishmaniasis);05140(Leishmaniasis)","K06752","NA","major histocompatibility complex, class II, DQ alpha 1 [Source:HGNC Symbol;Acc:HGNC:4942];major histocompatibility complex, class II, DQ alpha 2 [Source:HGNC Symbol;Acc:HGNC:4943]",{"v":1.23300173091942,"d":"1.23"},{"v":2.13256759353923,"d":"2.13"},{"v":0.57817709255964,"d":"0.58"},{"v":-0.790416644677191,"d":"-0.79"},{"v":0.112078976830513,"d":"0.11"},{"v":0.66435003808063,"d":"0.66"},"down","no"]
["ENSG00000197021","CXorf40B","ENST00000370406;ENST00000355203;ENST00000370404;ENST00000370409;ENST00000462691;ENST00000497550","NA","NA","NA","NA","chromosome X open reading frame 40B [Source:HGNC Symbol;Acc:HGNC:17402]",{"v":2.29708898326026,"d":"2.30"},{"v":3.97898211757672,"d":"3.98"},{"v":0.577305681549339,"d":"0.58"},{"v":-0.792592671199864,"d":"-0.79"},{"v":0.112150487167371,"d":"0.11"},{"v":0.66435003808063,"d":"0.66"},"down","no"]
["MSTRG.15529","FUNDC2","ENST00000369498;ENST00000485289;ENST00000456179;ENST00000475165;ENST00000484175;ENST00000492303;ENST00000471528","GO:0005634(nucleus);GO:0005739(mitochondrion);GO:0000422(mitophagy);GO:0031307(integral component of mitochondrial outer membrane);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016021(integral component of membrane)","NA","NA","NA","FUN14 domain containing 2 [Source:HGNC Symbol;Acc:HGNC:24925]",{"v":4.00239635554038,"d":"4.00"},{"v":6.88349331008584,"d":"6.88"},{"v":0.581448426727747,"d":"0.58"},{"v":-0.782276861578873,"d":"-0.78"},{"v":0.112194769190906,"d":"0.11"},{"v":0.66435003808063,"d":"0.66"},"down","no"]
["ENSG00000178096","BOLA1","ENST00000369152;ENST00000369153;ENST00000369150","GO:0005739(mitochondrion);GO:0005515(protein binding);GO:0005515(protein binding)","NA","NA","NA","bolA family member 1 [Source:HGNC Symbol;Acc:HGNC:24263]",{"v":1.28802874401095,"d":"1.29"},{"v":2.2712802128679,"d":"2.27"},{"v":0.567093719530353,"d":"0.57"},{"v":-0.818340916106858,"d":"-0.82"},{"v":0.112245533520833,"d":"0.11"},{"v":0.66435003808063,"d":"0.66"},"down","no"]
["MSTRG.2574","BANF1","ENST00000312175;ENST00000445560;ENST00000524628;ENST00000528648;ENST00000533166;MSTRG.2574.2;ENST00000527348;ENST00000524663;MSTRG.2574.1;ENST00000530204","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0003677(DNA binding);GO:0005694(chromosome);GO:0042803(protein homodimerization activity);GO:0005515(protein binding);GO:0015074(DNA integration);GO:0000793(condensed chromosome);GO:0070062(extracellular exosome);GO:0045071(negative regulation of viral genome replication);GO:0016032(viral process);GO:0008022(protein C-terminus binding);GO:0047485(protein N-terminus binding);GO:0019899(enzyme binding);GO:0009615(response to virus);GO:0007077(mitotic nuclear envelope disassembly);GO:0051169(nuclear transport);GO:0075713(establishment of integrated proviral latency);GO:0097726(LEM domain binding);GO:0007084(mitotic nuclear envelope reassembly);GO:0007084(mitotic nuclear envelope reassembly)","NA","NA","NA","barrier to autointegration factor 1 [Source:HGNC Symbol;Acc:HGNC:17397]",{"v":12.344943480297,"d":"12.34"},{"v":21.2278214568818,"d":"21.23"},{"v":0.581545473489693,"d":"0.58"},{"v":-0.782036088377064,"d":"-0.78"},{"v":0.112252609372602,"d":"0.11"},{"v":0.66435003808063,"d":"0.66"},"down","no"]
["ENSG00000109680","TBC1D19","ENST00000264866;ENST00000513455;ENST00000502873;ENST00000515568","GO:0043547(positive regulation of GTPase activity);GO:0005096(GTPase activator activity);GO:0005515(protein binding);GO:0005515(protein binding)","NA","NA","NA","TBC1 domain family member 19 [Source:HGNC Symbol;Acc:HGNC:25624]",{"v":0.317842106290041,"d":"0.32"},{"v":0.568066631624927,"d":"0.57"},{"v":0.559515536726509,"d":"0.56"},{"v":-0.837749902118089,"d":"-0.84"},{"v":0.112376336991767,"d":"0.11"},{"v":0.66435003808063,"d":"0.66"},"down","no"]
["MSTRG.8312","RPS11","ENST00000594493;ENST00000601306;ENST00000600027;ENST00000270625;ENST00000602252;ENST00000601216;ENST00000596873;ENST00000599561;ENST00000599167","GO:0003723(RNA binding);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0006412(translation);GO:0030529(intracellular ribonucleoprotein complex);GO:0005622(intracellular);GO:0003735(structural constituent of ribosome);GO:0005840(ribosome);GO:0005515(protein binding);GO:0022627(cytosolic small ribosomal subunit);GO:0005730(nucleolus);GO:0005925(focal adhesion);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0031012(extracellular matrix);GO:0019843(rRNA binding);GO:0006413(translational initiation);GO:0006364(rRNA processing);GO:0000184(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay);GO:0019083(viral transcription);GO:0006614(SRP-dependent cotranslational protein targeting to membrane);GO:0001649(osteoblast differentiation);GO:0001649(osteoblast differentiation)","03010(Ribosome);03010(Ribosome)","K02949","NA","ribosomal protein S11 [Source:HGNC Symbol;Acc:HGNC:10384]",{"v":381.503112469784,"d":"381.50"},{"v":654.553388338129,"d":"654.55"},{"v":0.582844912679158,"d":"0.58"},{"v":-0.778816042462729,"d":"-0.78"},{"v":0.112483450272813,"d":"0.11"},{"v":0.66435003808063,"d":"0.66"},"down","no"]
["MSTRG.344","PUM1","ENST00000373747;ENST00000440538;ENST00000426105;ENST00000257075;ENST00000524516;ENST00000525997;ENST00000480602;ENST00000373742;ENST00000471894;ENST00000498627;ENST00000532678;ENST00000424085;ENST00000526128;ENST00000525843;ENST00000498419;ENST00000373741;ENST00000525948;ENST00000490546;ENST00000530669","GO:0003723(RNA binding);GO:0016607(nuclear speck);GO:0005634(nucleus);GO:0005829(cytosol);GO:0005737(cytoplasm);GO:0005654(nucleoplasm);GO:0030154(cell differentiation);GO:0007283(spermatogenesis);GO:0000932(P-body);GO:0005515(protein binding);GO:0006417(regulation of translation);GO:0048863(stem cell differentiation);GO:2000637(positive regulation of gene silencing by miRNA);GO:0010494(cytoplasmic stress granule);GO:0051726(regulation of cell cycle);GO:0003730(mRNA 3'-UTR binding);GO:0051983(regulation of chromosome segregation);GO:1900246(positive regulation of RIG-I signaling pathway);GO:0008344(adult locomotory behavior);GO:0043488(regulation of mRNA stability);GO:0060964(regulation of gene silencing by miRNA);GO:0010608(posttranscriptional regulation of gene expression);GO:0016441(posttranscriptional gene silencing);GO:0061157(mRNA destabilization);GO:0061157(mRNA destabilization)","NA","NA","NA","pumilio RNA binding family member 1 [Source:HGNC Symbol;Acc:HGNC:14957]",{"v":9.89192478673916,"d":"9.89"},{"v":3.95489484231989,"d":"3.95"},{"v":2.50118528586128,"d":"2.50"},{"v":1.32261193520456,"d":"1.32"},{"v":0.112688139308542,"d":"0.11"},{"v":0.66435003808063,"d":"0.66"},"up","no"]
["MSTRG.5959","CIAPIN1","ENST00000394391;ENST00000567518;ENST00000569979;ENST00000566284;ENST00000569370;ENST00000564885;ENST00000563561;ENST00000565368;ENST00000569246;ENST00000565961;ENST00000568940","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0005654(nucleoplasm);GO:0008168(methyltransferase activity);GO:0005739(mitochondrion);GO:0008152(metabolic process);GO:0005515(protein binding);GO:0006915(apoptotic process);GO:0032259(methylation);GO:0051536(iron-sulfur cluster binding);GO:0005730(nucleolus);GO:0016226(iron-sulfur cluster assembly);GO:0051537(2 iron, 2 sulfur cluster binding);GO:0005758(mitochondrial intermembrane space);GO:0043066(negative regulation of apoptotic process);GO:0030097(hemopoiesis);GO:0030097(hemopoiesis)","NA","NA","NA","cytokine induced apoptosis inhibitor 1 [Source:HGNC Symbol;Acc:HGNC:28050]",{"v":3.27771863009404,"d":"3.28"},{"v":5.66234758677686,"d":"5.66"},{"v":0.578862137984679,"d":"0.58"},{"v":-0.788708298534935,"d":"-0.79"},{"v":0.11276474946642,"d":"0.11"},{"v":0.66435003808063,"d":"0.66"},"down","no"]
["MSTRG.5406","ANPEP","MSTRG.5406.1;ENST00000560137;ENST00000300060;ENST00000560030;ENST00000559761;ENST00000559874;ENST00000558177;ENST00000560028;ENST00000559887;ENST00000558740","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0005634(nucleus);GO:0016787(hydrolase activity);GO:0005765(lysosomal membrane);GO:0005886(plasma membrane);GO:0008233(peptidase activity);GO:0006508(proteolysis);GO:0007275(multicellular organism development);GO:0005615(extracellular space);GO:0030154(cell differentiation);GO:0008237(metallopeptidase activity);GO:0004177(aminopeptidase activity);GO:0009897(external side of plasma membrane);GO:0046718(viral entry into host cell);GO:0070062(extracellular exosome);GO:0007165(signal transduction);GO:0007267(cell-cell signaling);GO:0016032(viral process);GO:0043312(neutrophil degranulation);GO:0004872(receptor activity);GO:0030667(secretory granule membrane);GO:0001525(angiogenesis);GO:0001618(virus receptor activity);GO:0005793(endoplasmic reticulum-Golgi intermediate compartment);GO:0042277(peptide binding);GO:0070006(metalloaminopeptidase activity);GO:0008217(regulation of blood pressure);GO:0043171(peptide catabolic process);GO:0043171(peptide catabolic process)","00480(Glutathione metabolism);04640(Hematopoietic cell lineage);04614(Renin-angiotensin system);04614(Renin-angiotensin system)","K11140","EC:3.4.11.2","alanyl aminopeptidase, membrane [Source:HGNC Symbol;Acc:HGNC:500]",{"v":72.3327366799425,"d":"72.33"},{"v":29.0319361732704,"d":"29.03"},{"v":2.49148855413023,"d":"2.49"},{"v":1.31700794631224,"d":"1.32"},{"v":0.112765224090605,"d":"0.11"},{"v":0.66435003808063,"d":"0.66"},"up","no"]
["MSTRG.13174","PRDM1","ENST00000369089;ENST00000369096;ENST00000424894;ENST00000450060;ENST00000489365;ENST00000369091;ENST00000481163","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0008168(methyltransferase activity);GO:0016740(transferase activity);GO:0032259(methylation);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0002376(immune system process);GO:0045087(innate immune response);GO:0002250(adaptive immune response);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:0001078(transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0005654(nucleoplasm);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:1990841(promoter-specific chromatin binding);GO:0032823(regulation of natural killer cell differentiation);GO:0033082(regulation of extrathymic T cell differentiation);GO:0051136(regulation of NK T cell differentiation);GO:0042826(histone deacetylase binding);GO:0043565(sequence-specific DNA binding);GO:0001701(in utero embryonic development);GO:0001763(morphogenesis of a branching structure);GO:0001892(embryonic placenta development);GO:0001893(maternal placenta development);GO:0003170(heart valve development);GO:0003279(cardiac septum development);GO:0003281(ventricular septum development);GO:0007281(germ cell development);GO:0009791(post-embryonic development);GO:0010628(positive regulation of gene expression);GO:0010629(negative regulation of gene expression);GO:0030889(negative regulation of B cell proliferation);GO:0031665(negative regulation of lipopolysaccharide-mediated signaling pathway);GO:0035904(aorta development);GO:0042127(regulation of cell proliferation);GO:0042462(eye photoreceptor cell development);GO:0045165(cell fate commitment);GO:0045579(positive regulation of B cell differentiation);GO:0048844(artery morphogenesis);GO:0060576(intestinal epithelial cell development);GO:0060707(trophoblast giant cell differentiation);GO:0060976(coronary vasculature development);GO:1990654(sebum secreting cell proliferation);GO:1990654(sebum secreting cell proliferation)","NA","NA","NA","PR/SET domain 1 [Source:HGNC Symbol;Acc:HGNC:9346]",{"v":9.85252191380122,"d":"9.85"},{"v":3.943928059664,"d":"3.94"},{"v":2.4981495008914,"d":"2.50"},{"v":1.3208598171143,"d":"1.32"},{"v":0.112789700639693,"d":"0.11"},{"v":0.66435003808063,"d":"0.66"},"up","no"]
["ENSG00000145734","BDP1","ENST00000358731;ENST00000508917;ENST00000514903;ENST00000508157","GO:0005634(nucleus);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0001026(TFIIIB-type transcription factor activity);GO:0006359(regulation of transcription from RNA polymerase III promoter);GO:0006383(transcription from RNA polymerase III promoter);GO:0000126(transcription factor TFIIIB complex);GO:0005654(nucleoplasm);GO:0001156(TFIIIC-class transcription factor binding);GO:0070898(RNA polymerase III transcriptional preinitiation complex assembly);GO:0070898(RNA polymerase III transcriptional preinitiation complex assembly)","NA","NA","NA","B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB [Source:HGNC Symbol;Acc:HGNC:13652]",{"v":3.46230829374397,"d":"3.46"},{"v":1.38642507373754,"d":"1.39"},{"v":2.49729203498191,"d":"2.50"},{"v":1.32036454084347,"d":"1.32"},{"v":0.112852899395822,"d":"0.11"},{"v":0.66435003808063,"d":"0.66"},"up","no"]
["MSTRG.4885","SLC12A6","ENST00000560611;ENST00000397707;ENST00000290209;ENST00000559236;ENST00000559076;ENST00000560164;ENST00000558950;ENST00000558667;ENST00000560023;ENST00000559664;ENST00000561080;ENST00000559441","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005215(transporter activity);GO:0055085(transmembrane transport);GO:0006811(ion transport);GO:0005887(integral component of plasma membrane);GO:0015293(symporter activity);GO:0006813(potassium ion transport);GO:0005886(plasma membrane);GO:0071805(potassium ion transmembrane transport);GO:0015377(cation:chloride symporter activity);GO:0015379(potassium:chloride symporter activity);GO:0071477(cellular hypotonic salinity response);GO:1902476(chloride transmembrane transport);GO:0022820(potassium ion symporter activity);GO:0016323(basolateral plasma membrane);GO:0007268(chemical synaptic transmission);GO:0001525(angiogenesis);GO:0001525(angiogenesis)","NA","NA","NA","solute carrier family 12 member 6 [Source:HGNC Symbol;Acc:HGNC:10914]",{"v":12.8931980822395,"d":"12.89"},{"v":5.17361796708433,"d":"5.17"},{"v":2.49210478320371,"d":"2.49"},{"v":1.31736472928898,"d":"1.32"},{"v":0.112947412962367,"d":"0.11"},{"v":0.66435003808063,"d":"0.66"},"up","no"]
["MSTRG.10073","AGPAT3","MSTRG.10073.1","NA","NA","NA","NA",null,{"v":9.332774,"d":"9.33"},{"v":16.076357,"d":"16.08"},{"v":0.580527914377617,"d":"0.58"},{"v":-0.784562654900889,"d":"-0.78"},{"v":0.112958036511225,"d":"0.11"},{"v":0.66435003808063,"d":"0.66"},"down","no"]
["MSTRG.12875","LY6G6F;LY6G6D;AL662899.2","ENST00000375832;ENST00000375824;ENST00000503322","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005886(plasma membrane);GO:0002576(platelet degranulation);GO:0031092(platelet alpha granule membrane);GO:0042995(cell projection);GO:0031225(anchored component of membrane);GO:0005576(extracellular region);GO:0030550(acetylcholine receptor inhibitor activity);GO:0042802(identical protein binding);GO:0051260(protein homooligomerization);GO:0095500(acetylcholine receptor signaling pathway);GO:2000272(negative regulation of receptor activity);GO:0009897(external side of plasma membrane);GO:0043234(protein complex);GO:0030175(filopodium);GO:0006501(C-terminal protein lipidation);GO:0016021(integral component of membrane)","NA","NA","NA","lymphocyte antigen 6 family member G6F [Source:HGNC Symbol;Acc:HGNC:13933];lymphocyte antigen 6 family member G6D [Source:HGNC Symbol;Acc:HGNC:13935]",{"v":3.30042487621359,"d":"3.30"},{"v":5.69494468143204,"d":"5.69"},{"v":0.579535897332662,"d":"0.58"},{"v":-0.787030068168405,"d":"-0.79"},{"v":0.112959202895526,"d":"0.11"},{"v":0.66435003808063,"d":"0.66"},"down","no"]
["ENSG00000091164","TXNL1","ENST00000588615;ENST00000589931;ENST00000587807;ENST00000217515;ENST00000587613;ENST00000590954;ENST00000586262","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0055114(oxidation-reduction process);GO:0045454(cell redox homeostasis);GO:0000502(proteasome complex);GO:0098869(cellular oxidant detoxification);GO:0070062(extracellular exosome);GO:0004791(thioredoxin-disulfide reductase activity);GO:0015035(protein disulfide oxidoreductase activity);GO:0015036(disulfide oxidoreductase activity);GO:0016671(oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor);GO:0047134(protein-disulfide reductase activity);GO:0034599(cellular response to oxidative stress);GO:0005623(cell);GO:0006662(glycerol ether metabolic process);GO:0006662(glycerol ether metabolic process)","NA","NA","NA","thioredoxin like 1 [Source:HGNC Symbol;Acc:HGNC:12436]",{"v":2.03619344158258,"d":"2.04"},{"v":3.49563029217561,"d":"3.50"},{"v":0.582496794967209,"d":"0.58"},{"v":-0.779677983142135,"d":"-0.78"},{"v":0.113042139662632,"d":"0.11"},{"v":0.66435003808063,"d":"0.66"},"down","no"]
["MSTRG.14708","NDUFB6","ENST00000379847;ENST00000366466;ENST00000350021","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005654(nucleoplasm);GO:0055114(oxidation-reduction process);GO:0005739(mitochondrion);GO:0005743(mitochondrial inner membrane);GO:0070469(respiratory chain);GO:0031966(mitochondrial membrane);GO:0032981(mitochondrial respiratory chain complex I assembly);GO:0008137(NADH dehydrogenase (ubiquinone) activity);GO:0006120(mitochondrial electron transport, NADH to ubiquinone);GO:0005747(mitochondrial respiratory chain complex I);GO:0042775(mitochondrial ATP synthesis coupled electron transport);GO:0042775(mitochondrial ATP synthesis coupled electron transport)","00190(Oxidative phosphorylation);04723(Retrograde endocannabinoid signaling);05010(Alzheimer's disease);05012(Parkinson's disease);05016(Huntington's disease);04932(Non-alcoholic fatty liver disease (NAFLD));04932(Non-alcoholic fatty liver disease (NAFLD))","K03962","NA","NADH:ubiquinone oxidoreductase subunit B6 [Source:HGNC Symbol;Acc:HGNC:7701]",{"v":1.74691974135447,"d":"1.75"},{"v":3.04878546685879,"d":"3.05"},{"v":0.572988739399348,"d":"0.57"},{"v":-0.803421308038428,"d":"-0.80"},{"v":0.113065236498755,"d":"0.11"},{"v":0.66435003808063,"d":"0.66"},"down","no"]
["MSTRG.10908","SLC25A20","ENST00000319017;ENST00000479050;ENST00000440964","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005829(cytosol);GO:0005739(mitochondrion);GO:0005743(mitochondrial inner membrane);GO:0006839(mitochondrial transport);GO:0006853(carnitine shuttle);GO:0005476(carnitine:acyl carnitine antiporter activity);GO:0015226(carnitine transmembrane transporter activity);GO:0015227(acyl carnitine transmembrane transporter activity);GO:0015879(carnitine transport);GO:1902603(carnitine transmembrane transport);GO:1902616(acyl carnitine transmembrane transport);GO:1902616(acyl carnitine transmembrane transport)","NA","NA","NA","solute carrier family 25 member 20 [Source:HGNC Symbol;Acc:HGNC:1421]",{"v":7.9518497320888,"d":"7.95"},{"v":13.6677939672048,"d":"13.67"},{"v":0.581794673754146,"d":"0.58"},{"v":-0.781418006052536,"d":"-0.78"},{"v":0.113067789459188,"d":"0.11"},{"v":0.66435003808063,"d":"0.66"},"down","no"]
["MSTRG.7168","C17orf80","ENST00000535032;ENST00000268942;ENST00000359042;ENST00000577615;ENST00000582391;ENST00000255557","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0003674(molecular_function);GO:0008150(biological_process);GO:0070062(extracellular exosome);GO:0070062(extracellular exosome)","NA","NA","NA","chromosome 17 open reading frame 80 [Source:HGNC Symbol;Acc:HGNC:29601]",{"v":1.59146058653228,"d":"1.59"},{"v":2.74931704396311,"d":"2.75"},{"v":0.578856698257763,"d":"0.58"},{"v":-0.788721856001219,"d":"-0.79"},{"v":0.113097175853304,"d":"0.11"},{"v":0.66435003808063,"d":"0.66"},"down","no"]
["MSTRG.13919","DOCK4","ENST00000428084;ENST00000486186;ENST00000476846;ENST00000492532;ENST00000468571;ENST00000469898;ENST00000445943;ENST00000417165;ENST00000423057","GO:0005622(intracellular);GO:0007264(small GTPase mediated signal transduction);GO:0043547(positive regulation of GTPase activity);GO:0005085(guanyl-nucleotide exchange factor activity);GO:1904754(positive regulation of vascular associated smooth muscle cell migration);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005794(Golgi apparatus);GO:0005730(nucleolus);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0042995(cell projection);GO:0005515(protein binding);GO:0017124(SH3 domain binding);GO:0030971(receptor tyrosine kinase binding);GO:0060326(cell chemotaxis);GO:0005096(GTPase activator activity);GO:0030165(PDZ domain binding);GO:0048365(Rac GTPase binding);GO:1904694(negative regulation of vascular smooth muscle contraction);GO:0032420(stereocilium);GO:0032421(stereocilium bundle);GO:0032421(stereocilium bundle)","04015(Rap1 signaling pathway);04015(Rap1 signaling pathway)","K17697","NA","dedicator of cytokinesis 4 [Source:HGNC Symbol;Acc:HGNC:19192]",{"v":0.834281618575528,"d":"0.83"},{"v":0.330402817810244,"d":"0.33"},{"v":2.52504389673417,"d":"2.53"},{"v":1.3363084686764,"d":"1.34"},{"v":0.113097923935632,"d":"0.11"},{"v":0.66435003808063,"d":"0.66"},"up","no"]
["MSTRG.9757","PKIG","ENST00000372886;ENST00000372894;ENST00000372889;ENST00000372887;ENST00000477390;ENST00000372891;ENST00000349959","GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0005515(protein binding);GO:0004860(protein kinase inhibitor activity);GO:0004862(cAMP-dependent protein kinase inhibitor activity);GO:0006469(negative regulation of protein kinase activity);GO:0071901(negative regulation of protein serine/threonine kinase activity);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:2000480(negative regulation of cAMP-dependent protein kinase activity);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0007165(signal transduction);GO:0042308(negative regulation of protein import into nucleus);GO:0042308(negative regulation of protein import into nucleus)","NA","NA","NA","cAMP-dependent protein kinase inhibitor gamma [Source:HGNC Symbol;Acc:HGNC:9019]",{"v":2.45651748036859,"d":"2.46"},{"v":4.24517073357372,"d":"4.25"},{"v":0.578661645087856,"d":"0.58"},{"v":-0.789208072474964,"d":"-0.79"},{"v":0.113143545076826,"d":"0.11"},{"v":0.66435003808063,"d":"0.66"},"down","no"]
["MSTRG.12463","DCTN4","ENST00000447998;ENST00000522625;ENST00000521728;ENST00000627368;ENST00000519313;ENST00000518015;ENST00000518909;ENST00000424236;ENST00000520195;ENST00000517421;ENST00000521093","GO:0005737(cytoplasm);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0005813(centrosome);GO:0005815(microtubule organizing center);GO:0005869(dynactin complex);GO:0005829(cytosol);GO:0019886(antigen processing and presentation of exogenous peptide antigen via MHC class II);GO:0005634(nucleus);GO:0047485(protein N-terminus binding);GO:0006888(ER to Golgi vesicle-mediated transport);GO:0005868(cytoplasmic dynein complex);GO:0007097(nuclear migration);GO:0007097(nuclear migration)","04962(Vasopressin-regulated water reabsorption);05016(Huntington's disease);05016(Huntington's disease)","K10426","NA","dynactin subunit 4 [Source:HGNC Symbol;Acc:HGNC:15518]",{"v":2.41497253607605,"d":"2.41"},{"v":4.15837076032414,"d":"4.16"},{"v":0.580749691469985,"d":"0.58"},{"v":-0.784011612301564,"d":"-0.78"},{"v":0.1131563226835,"d":"0.11"},{"v":0.66435003808063,"d":"0.66"},"down","no"]
["ENSG00000121274","PAPD5","ENST00000436909;ENST00000562717;ENST00000357464;ENST00000561678","GO:0003723(RNA binding);GO:0006397(mRNA processing);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0016740(transferase activity);GO:0003677(DNA binding);GO:0051301(cell division);GO:0007049(cell cycle);GO:0016779(nucleotidyltransferase activity);GO:0003887(DNA-directed DNA polymerase activity);GO:0071897(DNA biosynthetic process);GO:0005730(nucleolus);GO:0006364(rRNA processing);GO:0005575(cellular_component);GO:0070034(telomerase RNA binding);GO:0071044(histone mRNA catabolic process);GO:0032211(negative regulation of telomere maintenance via telomerase);GO:0004652(polynucleotide adenylyltransferase activity);GO:0043630(ncRNA polyadenylation involved in polyadenylation-dependent ncRNA catabolic process);GO:0043630(ncRNA polyadenylation involved in polyadenylation-dependent ncRNA catabolic process)","03018(RNA degradation);03018(RNA degradation)","K03514","EC:2.7.7.19","poly(A) RNA polymerase D5, non-canonical [Source:HGNC Symbol;Acc:HGNC:30758]",{"v":1.8668736081778,"d":"1.87"},{"v":0.743544392681729,"d":"0.74"},{"v":2.51077625835436,"d":"2.51"},{"v":1.32813347212015,"d":"1.33"},{"v":0.113284631043364,"d":"0.11"},{"v":0.664434615435505,"d":"0.66"},"up","no"]
["MSTRG.2507","TRMT112","ENST00000539854;ENST00000535750;ENST00000544844;ENST00000537918;ENST00000308774;MSTRG.2507.2;ENST00000535126","GO:0005515(protein binding);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0043234(protein complex);GO:0031167(rRNA methylation);GO:0070476(rRNA (guanine-N7)-methylation);GO:0030488(tRNA methylation);GO:0032259(methylation);GO:0006415(translational termination);GO:0008276(protein methyltransferase activity);GO:0018364(peptidyl-glutamine methylation);GO:0018364(peptidyl-glutamine methylation)","NA","NA","NA","tRNA methyltransferase subunit 11-2 [Source:HGNC Symbol;Acc:HGNC:26940]",{"v":15.0040483969231,"d":"15.00"},{"v":25.7663578590769,"d":"25.77"},{"v":0.582311573835319,"d":"0.58"},{"v":-0.780136801292579,"d":"-0.78"},{"v":0.113389739294531,"d":"0.11"},{"v":0.664434615435505,"d":"0.66"},"down","no"]
["ENSG00000077514","POLD3","ENST00000263681;ENST00000527458;ENST00000524752;ENST00000530163;ENST00000530511;ENST00000532784;ENST00000531615;ENST00000532954","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005515(protein binding);GO:0006281(DNA repair);GO:0006974(cellular response to DNA damage stimulus);GO:0006260(DNA replication);GO:0003887(DNA-directed DNA polymerase activity);GO:0006261(DNA-dependent DNA replication);GO:0006298(mismatch repair);GO:0005654(nucleoplasm);GO:0019985(translesion synthesis);GO:0006283(transcription-coupled nucleotide-excision repair);GO:0042769(DNA damage response, detection of DNA damage);GO:0006296(nucleotide-excision repair, DNA incision, 5'-to lesion);GO:0033683(nucleotide-excision repair, DNA incision);GO:0032201(telomere maintenance via semi-conservative replication);GO:0006297(nucleotide-excision repair, DNA gap filling);GO:0000723(telomere maintenance);GO:0006266(DNA ligation);GO:0000731(DNA synthesis involved in DNA repair);GO:0043625(delta DNA polymerase complex);GO:0043625(delta DNA polymerase complex)","00230(Purine metabolism);00240(Pyrimidine metabolism);03030(DNA replication);03410(Base excision repair);03420(Nucleotide excision repair);03430(Mismatch repair);03440(Homologous recombination);05166(HTLV-I infection);05166(HTLV-I infection)","K03504","NA","DNA polymerase delta 3, accessory subunit [Source:HGNC Symbol;Acc:HGNC:20932]",{"v":1.65749806608569,"d":"1.66"},{"v":2.86378177378359,"d":"2.86"},{"v":0.578779459126114,"d":"0.58"},{"v":-0.788914373333453,"d":"-0.79"},{"v":0.113431738087423,"d":"0.11"},{"v":0.664434615435505,"d":"0.66"},"down","no"]
["ENSG00000180229","HERC2P3","ENST00000429926;ENST00000412154;ENST00000424611;ENST00000456027;ENST00000414804;ENST00000429257;ENST00000454045;ENST00000437318;ENST00000428453;ENST00000426501;ENST00000430598","NA","NA","NA","NA","hect domain and RLD 2 pseudogene 3 [Source:HGNC Symbol;Acc:HGNC:4871]",{"v":0.555977388186551,"d":"0.56"},{"v":0.218241574312122,"d":"0.22"},{"v":2.54753197203119,"d":"2.55"},{"v":1.34910025261342,"d":"1.35"},{"v":0.113488048829245,"d":"0.11"},{"v":0.664434615435505,"d":"0.66"},"up","no"]
["MSTRG.7707","NDUFA11;AC024592.3","ENST00000308961;ENST00000592634;ENST00000591160;ENST00000593233;ENST00000592091;ENST00000591341;ENST00000585661;ENST00000418389;ENST00000586349","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0055114(oxidation-reduction process);GO:0005739(mitochondrion);GO:0005743(mitochondrial inner membrane);GO:0070469(respiratory chain);GO:0032981(mitochondrial respiratory chain complex I assembly);GO:0006120(mitochondrial electron transport, NADH to ubiquinone);GO:0005747(mitochondrial respiratory chain complex I);GO:0005747(mitochondrial respiratory chain complex I)","00190(Oxidative phosphorylation);04723(Retrograde endocannabinoid signaling);05010(Alzheimer's disease);05012(Parkinson's disease);05016(Huntington's disease);04932(Non-alcoholic fatty liver disease (NAFLD));04932(Non-alcoholic fatty liver disease (NAFLD))","K03956","NA","NADH:ubiquinone oxidoreductase subunit A11 [Source:HGNC Symbol;Acc:HGNC:20371]",{"v":2.56962885203934,"d":"2.57"},{"v":4.41677492421174,"d":"4.42"},{"v":0.581788498651636,"d":"0.58"},{"v":-0.781433318734912,"d":"-0.78"},{"v":0.113510712262874,"d":"0.11"},{"v":0.664434615435505,"d":"0.66"},"down","no"]
["MSTRG.13001","PIM1","ENST00000373509;ENST00000468243;ENST00000479509","GO:0060045(positive regulation of cardiac muscle cell proliferation);GO:0005737(cytoplasm);GO:0005634(nucleus);GO:0016020(membrane);GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0043066(negative regulation of apoptotic process);GO:0005730(nucleolus);GO:0005829(cytosol);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0007049(cell cycle);GO:0006915(apoptotic process);GO:0030212(hyaluronan metabolic process);GO:0005654(nucleoplasm);GO:0008283(cell proliferation);GO:0007275(multicellular organism development);GO:0008134(transcription factor binding);GO:0043433(negative regulation of sequence-specific DNA binding transcription factor activity);GO:0046777(protein autophosphorylation);GO:0007346(regulation of mitotic cell cycle);GO:0043024(ribosomal small subunit binding);GO:0030145(manganese ion binding);GO:0070561(vitamin D receptor signaling pathway);GO:1905062(positive regulation of cardioblast proliferation);GO:1905062(positive regulation of cardioblast proliferation)","04630(Jak-STAT signaling pathway);05200(Pathways in cancer);05206(MicroRNAs in cancer);05221(Acute myeloid leukemia);04933(AGE-RAGE signaling pathway in diabetic complications);04933(AGE-RAGE signaling pathway in diabetic complications)","K04702","EC:2.7.11.1","Pim-1 proto-oncogene, serine/threonine kinase [Source:HGNC Symbol;Acc:HGNC:8986]",{"v":17.8984686284851,"d":"17.90"},{"v":30.6726249381928,"d":"30.67"},{"v":0.583532340794164,"d":"0.58"},{"v":-0.777115479039765,"d":"-0.78"},{"v":0.113540090878017,"d":"0.11"},{"v":0.664434615435505,"d":"0.66"},"down","no"]
["MSTRG.12554","SIMC1","ENST00000429602;ENST00000332772;ENST00000503595;ENST00000341199;ENST00000495423;ENST00000508769;ENST00000443967","GO:0032184(SUMO polymer binding);GO:0032184(SUMO polymer binding)","NA","NA","NA","SUMO interacting motifs containing 1 [Source:HGNC Symbol;Acc:HGNC:24779]",{"v":1.20599119020954,"d":"1.21"},{"v":0.477527558887283,"d":"0.48"},{"v":2.52549024190289,"d":"2.53"},{"v":1.33656346743314,"d":"1.34"},{"v":0.113602207245547,"d":"0.11"},{"v":0.664434615435505,"d":"0.66"},"up","no"]
["MSTRG.2394","SERPING1","ENST00000531133;ENST00000528996;ENST00000378323;ENST00000531605;ENST00000531797;ENST00000403558;ENST00000530113;ENST00000278407","GO:0005615(extracellular space);GO:0004867(serine-type endopeptidase inhibitor activity);GO:0010951(negative regulation of endopeptidase activity);GO:0030193(regulation of blood coagulation);GO:0045916(negative regulation of complement activation);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0002376(immune system process);GO:0045087(innate immune response);GO:0030449(regulation of complement activation);GO:0030414(peptidase inhibitor activity);GO:0010466(negative regulation of peptidase activity);GO:0070062(extracellular exosome);GO:0072562(blood microparticle);GO:0007568(aging);GO:0006958(complement activation, classical pathway);GO:0002576(platelet degranulation);GO:0007596(blood coagulation);GO:0007599(hemostasis);GO:0031093(platelet alpha granule lumen);GO:0008015(blood circulation);GO:0007597(blood coagulation, intrinsic pathway);GO:0042730(fibrinolysis);GO:0001869(negative regulation of complement activation, lectin pathway);GO:0001869(negative regulation of complement activation, lectin pathway)","04610(Complement and coagulation cascades);05133(Pertussis);05133(Pertussis)","K04001","NA","serpin family G member 1 [Source:HGNC Symbol;Acc:HGNC:1228]",{"v":2.50031172522898,"d":"2.50"},{"v":0.993634051068554,"d":"0.99"},{"v":2.5163305570498,"d":"2.52"},{"v":1.33132145389115,"d":"1.33"},{"v":0.11362844624601,"d":"0.11"},{"v":0.664434615435505,"d":"0.66"},"up","no"]
["MSTRG.8008","COPE;HOMER3;AC002985.1","ENST00000262812;ENST00000349893;ENST00000392351;ENST00000599097;ENST00000539827;ENST00000600528;ENST00000542541;ENST00000595756;ENST00000593484;ENST00000593827;ENST00000600077;ENST00000600932;ENST00000596482;ENST00000594439;ENST00000595984;ENST00000351079;ENST00000599808;ENST00000597646;ENST00000598969;ENST00000594794;ENST00000596918;ENST00000597026","GO:0006810(transport);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0015031(protein transport);GO:0005794(Golgi apparatus);GO:0005654(nucleoplasm);GO:0005198(structural molecule activity);GO:0005515(protein binding);GO:0000139(Golgi membrane);GO:0006890(retrograde vesicle-mediated transport, Golgi to ER);GO:0031410(cytoplasmic vesicle);GO:0016192(vesicle-mediated transport);GO:0006891(intra-Golgi vesicle-mediated transport);GO:0030663(COPI-coated vesicle membrane);GO:0005789(endoplasmic reticulum membrane);GO:0005829(cytosol);GO:0006888(ER to Golgi vesicle-mediated transport);GO:0030133(transport vesicle);GO:0030126(COPI vesicle coat);GO:0030137(COPI-coated vesicle);GO:0005886(plasma membrane);GO:0030054(cell junction);GO:0045202(synapse);GO:0045211(postsynaptic membrane);GO:0005575(cellular_component);GO:0014069(postsynaptic density);GO:0006605(protein targeting);GO:0007216(G-protein coupled glutamate receptor signaling pathway);GO:0035256(G-protein coupled glutamate receptor binding);GO:0008022(protein C-terminus binding);GO:0019904(protein domain specific binding);GO:0045178(basal part of cell);GO:0030137(COPI-coated vesicle)","04068(FoxO signaling pathway);04724(Glutamatergic synapse);04724(Glutamatergic synapse)","K15010","NA","coatomer protein complex subunit epsilon [Source:HGNC Symbol;Acc:HGNC:2234];homer scaffolding protein 3 [Source:HGNC Symbol;Acc:HGNC:17514]",{"v":8.41558731694942,"d":"8.42"},{"v":14.4224234514032,"d":"14.42"},{"v":0.58350715781616,"d":"0.58"},{"v":-0.777177741469665,"d":"-0.78"},{"v":0.113805736947079,"d":"0.11"},{"v":0.66455664219549,"d":"0.66"},"down","no"]
["ENSG00000166436","TRIM66","ENST00000402157;ENST00000299550;ENST00000481014;ENST00000531498;ENST00000525788;ENST00000529057;ENST00000529211;ENST00000530502","GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0005654(nucleoplasm);GO:0005622(intracellular);GO:0016235(aggresome);GO:0005634(nucleus);GO:0005634(nucleus)","NA","NA","NA","tripartite motif containing 66 [Source:HGNC Symbol;Acc:HGNC:29005]",{"v":0.757973632026627,"d":"0.76"},{"v":0.300430402644231,"d":"0.30"},{"v":2.52295914579663,"d":"2.52"},{"v":1.33511684498492,"d":"1.34"},{"v":0.113830538978478,"d":"0.11"},{"v":0.66455664219549,"d":"0.66"},"up","no"]
["MSTRG.10460","GTPBP1","ENST00000216044;ENST00000462332;ENST00000475959;ENST00000470836;ENST00000484971;ENST00000488787;ENST00000487538;ENST00000458073;ENST00000418601;ENST00000461428;ENST00000460605","GO:0003723(RNA binding);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005525(GTP binding);GO:0000166(nucleotide binding);GO:0003924(GTPase activity);GO:0005829(cytosol);GO:0006955(immune response);GO:0007165(signal transduction);GO:0046039(GTP metabolic process);GO:0061014(positive regulation of mRNA catabolic process);GO:0000177(cytoplasmic exosome (RNase complex));GO:0000177(cytoplasmic exosome (RNase complex))","NA","NA","NA","GTP binding protein 1 [Source:HGNC Symbol;Acc:HGNC:4669]",{"v":3.71758919177076,"d":"3.72"},{"v":1.48886665160421,"d":"1.49"},{"v":2.49692555593556,"d":"2.50"},{"v":1.32015280897794,"d":"1.32"},{"v":0.113856557728621,"d":"0.11"},{"v":0.66455664219549,"d":"0.66"},"up","no"]
["MSTRG.3368","CERS5","ENST00000317551;ENST00000438450;ENST00000550258;ENST00000550079;ENST00000551757;ENST00000546676;ENST00000549942;ENST00000547455;ENST00000549389;ENST00000550899;ENST00000380189;ENST00000547787;ENST00000548930;ENST00000551384;ENST00000551005;ENST00000422340;ENST00000547800;ENST00000547852;ENST00000542320;ENST00000546514","GO:0005634(nucleus);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0003677(DNA binding);GO:0005783(endoplasmic reticulum);GO:0016740(transferase activity);GO:0006629(lipid metabolic process);GO:0005789(endoplasmic reticulum membrane);GO:0006665(sphingolipid metabolic process);GO:0031965(nuclear membrane);GO:0030148(sphingolipid biosynthetic process);GO:0050291(sphingosine N-acyltransferase activity);GO:0046513(ceramide biosynthetic process);GO:0046513(ceramide biosynthetic process)","00600(Sphingolipid metabolism);04071(Sphingolipid signaling pathway);04071(Sphingolipid signaling pathway)","K04710","EC:2.3.1.24","ceramide synthase 5 [Source:HGNC Symbol;Acc:HGNC:23749]",{"v":1.77029841932138,"d":"1.77"},{"v":3.04878357401096,"d":"3.05"},{"v":0.580657293752205,"d":"0.58"},{"v":-0.784241164441696,"d":"-0.78"},{"v":0.113923063035988,"d":"0.11"},{"v":0.66455664219549,"d":"0.66"},"down","no"]
["ENSG00000116962","NID1","ENST00000264187;ENST00000366595","GO:0005509(calcium ion binding);GO:0007155(cell adhesion);GO:0005576(extracellular region);GO:0005578(proteinaceous extracellular matrix);GO:0007160(cell-matrix adhesion);GO:0005604(basement membrane);GO:0070062(extracellular exosome);GO:0031012(extracellular matrix);GO:0030198(extracellular matrix organization);GO:0022617(extracellular matrix disassembly);GO:0071711(basement membrane organization);GO:0005518(collagen binding);GO:0043394(proteoglycan binding);GO:0043236(laminin binding);GO:0043237(laminin-1 binding);GO:0050840(extracellular matrix binding);GO:0010811(positive regulation of cell-substrate adhesion);GO:0032836(glomerular basement membrane development);GO:0005605(basal lamina);GO:0005615(extracellular space);GO:0071944(cell periphery);GO:0071944(cell periphery)","NA","NA","NA","nidogen 1 [Source:HGNC Symbol;Acc:HGNC:7821]",{"v":0.682272,"d":"0.68"},{"v":0.267631,"d":"0.27"},{"v":2.54930108993353,"d":"2.55"},{"v":1.35010177559678,"d":"1.35"},{"v":0.113935440851737,"d":"0.11"},{"v":0.66455664219549,"d":"0.66"},"up","no"]
["MSTRG.8100","SPINT2;C19orf33","ENST00000301244;ENST00000589749;ENST00000590738;ENST00000587090;ENST00000590510;ENST00000591852;ENST00000301246;ENST00000588605;ENST00000454580;ENST00000587334;ENST00000589986;ENST00000585357;ENST00000592007","GO:0004867(serine-type endopeptidase inhibitor activity);GO:0010951(negative regulation of endopeptidase activity);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0030414(peptidase inhibitor activity);GO:0010466(negative regulation of peptidase activity);GO:0005576(extracellular region);GO:0005737(cytoplasm);GO:0006928(movement of cell or subcellular component);GO:0004866(endopeptidase inhibitor activity);GO:0001843(neural tube closure);GO:0007163(establishment or maintenance of cell polarity);GO:0022408(negative regulation of cell-cell adhesion);GO:0060672(epithelial cell morphogenesis involved in placental branching);GO:0071711(basement membrane organization);GO:0071773(cellular response to BMP stimulus);GO:2000146(negative regulation of cell motility);GO:2000178(negative regulation of neural precursor cell proliferation);GO:0005886(plasma membrane);GO:0005634(nucleus);GO:0005829(cytosol);GO:0008150(biological_process);GO:0005886(plasma membrane)","NA","NA","NA","serine peptidase inhibitor, Kunitz type 2 [Source:HGNC Symbol;Acc:HGNC:11247];chromosome 19 open reading frame 33 [Source:HGNC Symbol;Acc:HGNC:16668]",{"v":3.52058501994498,"d":"3.52"},{"v":6.03531232513755,"d":"6.04"},{"v":0.583331040761796,"d":"0.58"},{"v":-0.777613248643131,"d":"-0.78"},{"v":0.114087999442431,"d":"0.11"},{"v":0.66511241843622,"d":"0.67"},"down","no"]
["MSTRG.215","DDOST;PINK1-AS","ENST00000375048;ENST00000602624;ENST00000415136;ENST00000451424;ENST00000477229;ENST00000464364;ENST00000475210","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005783(endoplasmic reticulum);GO:0016740(transferase activity);GO:0016757(transferase activity, transferring glycosyl groups);GO:0005789(endoplasmic reticulum membrane);GO:0006486(protein glycosylation);GO:0018279(protein N-linked glycosylation via asparagine);GO:0005515(protein binding);GO:0005886(plasma membrane);GO:0043231(intracellular membrane-bounded organelle);GO:0043234(protein complex);GO:0043312(neutrophil degranulation);GO:0004579(dolichyl-diphosphooligosaccharide-protein glycotransferase activity);GO:0042110(T cell activation);GO:0035577(azurophil granule membrane);GO:0006487(protein N-linked glycosylation);GO:0034097(response to cytokine);GO:0008250(oligosaccharyltransferase complex);GO:0004576(oligosaccharyl transferase activity);GO:0004576(oligosaccharyl transferase activity)","00510(N-Glycan biosynthesis);04141(Protein processing in endoplasmic reticulum);04141(Protein processing in endoplasmic reticulum)","K12670","NA","dolichyl-diphosphooligosaccharide--protein glycosyltransferase non-catalytic subunit [Source:HGNC Symbol;Acc:HGNC:2728];PINK1 antisense RNA [Source:HGNC Symbol;Acc:HGNC:38872]",{"v":8.42974394611845,"d":"8.43"},{"v":14.4253483041413,"d":"14.43"},{"v":0.584370218894361,"d":"0.58"},{"v":-0.775045438560132,"d":"-0.78"},{"v":0.114228060109201,"d":"0.11"},{"v":0.665339187401224,"d":"0.67"},"down","no"]
["MSTRG.10672","RPL32;SNORA7A","ENST00000452606;ENST00000435983;ENST00000396957;ENST00000396953;ENST00000429711;ENST00000457131;ENST00000273223;ENST00000434963;ENST00000384765","GO:0003723(RNA binding);GO:0016020(membrane);GO:0006412(translation);GO:0030529(intracellular ribonucleoprotein complex);GO:0005622(intracellular);GO:0003735(structural constituent of ribosome);GO:0005840(ribosome);GO:0071549(cellular response to dexamethasone stimulus);GO:0097421(liver regeneration);GO:0022625(cytosolic large ribosomal subunit);GO:0005829(cytosol);GO:0006413(translational initiation);GO:0006364(rRNA processing);GO:0000184(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay);GO:0019083(viral transcription);GO:0006614(SRP-dependent cotranslational protein targeting to membrane);GO:0006614(SRP-dependent cotranslational protein targeting to membrane)","03010(Ribosome);03010(Ribosome)","K02912","NA","ribosomal protein L32 [Source:HGNC Symbol;Acc:HGNC:10336];small nucleolar RNA, H/ACA box 7A [Source:HGNC Symbol;Acc:HGNC:32592]",{"v":92.2140423395161,"d":"92.21"},{"v":157.656461663978,"d":"157.66"},{"v":0.584904934223737,"d":"0.58"},{"v":-0.773725935266666,"d":"-0.77"},{"v":0.114241482793252,"d":"0.11"},{"v":0.665339187401224,"d":"0.67"},"down","no"]
["MSTRG.13672","BAZ1B","ENST00000404251;ENST00000339594;ENST00000466844","GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0004713(protein tyrosine kinase activity);GO:0018108(peptidyl-tyrosine phosphorylation);GO:0008270(zinc ion binding);GO:0005515(protein binding);GO:0006974(cellular response to DNA damage stimulus);GO:0016604(nuclear body);GO:0004715(non-membrane spanning protein tyrosine kinase activity);GO:2000273(positive regulation of receptor activity);GO:0005654(nucleoplasm);GO:0003682(chromatin binding);GO:0045815(positive regulation of gene expression, epigenetic);GO:0070577(lysine-acetylated histone binding);GO:0003007(heart morphogenesis);GO:0043596(nuclear replication fork);GO:0016572(histone phosphorylation);GO:0035173(histone kinase activity);GO:0006302(double-strand break repair);GO:0042393(histone binding);GO:0071884(vitamin D receptor activator activity);GO:0006333(chromatin assembly or disassembly);GO:0006338(chromatin remodeling);GO:0048096(chromatin-mediated maintenance of transcription);GO:0000793(condensed chromosome);GO:0005721(pericentric heterochromatin);GO:0005721(pericentric heterochromatin)","NA","NA","NA","bromodomain adjacent to zinc finger domain 1B [Source:HGNC Symbol;Acc:HGNC:961]",{"v":7.8381051654615,"d":"7.84"},{"v":3.15123325223309,"d":"3.15"},{"v":2.48731354935631,"d":"2.49"},{"v":1.31458838434949,"d":"1.31"},{"v":0.114471603101887,"d":"0.11"},{"v":0.6663452264773,"d":"0.67"},"up","no"]
["ENSG00000172915","NBEA","ENST00000400445;ENST00000629018;ENST00000497540","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0005802(trans-Golgi network);GO:0012505(endomembrane system);GO:0019901(protein kinase binding);GO:0008104(protein localization);GO:0008104(protein localization)","NA","NA","NA","neurobeachin [Source:HGNC Symbol;Acc:HGNC:7648]",{"v":0.186579406895975,"d":"0.19"},{"v":0.0712336236505147,"d":"0.07"},{"v":2.6192603623728,"d":"2.62"},{"v":1.38915947505102,"d":"1.39"},{"v":0.114554500103826,"d":"0.11"},{"v":0.666493692237343,"d":"0.67"},"up","no"]
["ENSG00000021574","SPAST","ENST00000615843;ENST00000621856;ENST00000315285;ENST00000345662","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0016787(hydrolase activity);GO:0051301(cell division);GO:1904115(axon cytoplasm);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005856(cytoskeleton);GO:0003824(catalytic activity);GO:0008152(metabolic process);GO:0007049(cell cycle);GO:0007275(multicellular organism development);GO:0048471(perinuclear region of cytoplasm);GO:0007399(nervous system development);GO:0030154(cell differentiation);GO:0005874(microtubule);GO:0008017(microtubule binding);GO:0008568(microtubule-severing ATPase activity);GO:0051013(microtubule severing);GO:0005813(centrosome);GO:0005815(microtubule organizing center);GO:0005819(spindle);GO:0030496(midbody);GO:0005515(protein binding);GO:0005768(endosome);GO:0007409(axonogenesis);GO:0015630(microtubule cytoskeleton);GO:0070062(extracellular exosome);GO:0043014(alpha-tubulin binding);GO:0006888(ER to Golgi vesicle-mediated transport);GO:0031117(positive regulation of microtubule depolymerization);GO:0032506(cytokinetic process);GO:0034214(protein hexamerization);GO:0031965(nuclear membrane);GO:0008089(anterograde axonal transport);GO:0005811(lipid particle);GO:0010458(exit from mitosis);GO:0000281(mitotic cytokinesis);GO:0032467(positive regulation of cytokinesis);GO:0031410(cytoplasmic vesicle);GO:0048487(beta-tubulin binding);GO:0051260(protein homooligomerization);GO:0031468(nuclear envelope reassembly);GO:0001578(microtubule bundle formation);GO:0019896(axonal transport of mitochondrion);GO:0000815(ESCRT III complex);GO:0090148(membrane fission);GO:0006998(nuclear envelope organization);GO:0051228(mitotic spindle disassembly);GO:0051230(spindle disassembly);GO:0061640(cytoskeleton-dependent cytokinesis);GO:0061640(cytoskeleton-dependent cytokinesis)","NA","NA","NA","spastin [Source:HGNC Symbol;Acc:HGNC:11233]",{"v":5.32389991808939,"d":"5.32"},{"v":2.13780182505275,"d":"2.14"},{"v":2.49036176117869,"d":"2.49"},{"v":1.31635532990343,"d":"1.32"},{"v":0.114647186197908,"d":"0.11"},{"v":0.666698935060742,"d":"0.67"},"up","no"]
["ENSG00000165219","GAPVD1","ENST00000394083;ENST00000470056;ENST00000394105;ENST00000467707;ENST00000479511;ENST00000497580;ENST00000474637;ENST00000467750;ENST00000495588;ENST00000431329;ENST00000495955;ENST00000469528;ENST00000469498;ENST00000461379;ENST00000312123;ENST00000436712;ENST00000394104;ENST00000297933;ENST00000394084","GO:0007165(signal transduction);GO:0043087(regulation of GTPase activity);GO:0016020(membrane);GO:0005829(cytosol);GO:0043547(positive regulation of GTPase activity);GO:0005096(GTPase activator activity);GO:0005085(guanyl-nucleotide exchange factor activity);GO:0032794(GTPase activating protein binding);GO:0051223(regulation of protein transport);GO:0005768(endosome);GO:0045296(cadherin binding);GO:0006897(endocytosis);GO:0017112(Rab guanyl-nucleotide exchange factor activity);GO:0061024(membrane organization);GO:0061024(membrane organization)","NA","NA","NA","GTPase activating protein and VPS9 domains 1 [Source:HGNC Symbol;Acc:HGNC:23375]",{"v":3.97695501225688,"d":"3.98"},{"v":1.59846322847706,"d":"1.60"},{"v":2.48798654945972,"d":"2.49"},{"v":1.31497868599897,"d":"1.31"},{"v":0.114745099192052,"d":"0.11"},{"v":0.666857321955886,"d":"0.67"},"up","no"]
["MSTRG.6284","PITPNA-AS1","ENST00000425081","NA","NA","NA","NA","PITPNA antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:44116]",{"v":1.492628,"d":"1.49"},{"v":2.723339,"d":"2.72"},{"v":0.548087476439768,"d":"0.55"},{"v":-0.867521924777815,"d":"-0.87"},{"v":0.114896206826228,"d":"0.11"},{"v":0.666857321955886,"d":"0.67"},"down","no"]
["MSTRG.14758","CREB3","ENST00000353704;ENST00000486056","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005829(cytosol);GO:0006355(regulation of transcription, DNA-templated);GO:0006366(transcription from RNA polymerase II promoter);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005515(protein binding);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0006935(chemotaxis);GO:0035497(cAMP response element binding);GO:0030968(endoplasmic reticulum unfolded protein response);GO:0006986(response to unfolded protein);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:0005654(nucleoplasm);GO:0016032(viral process);GO:0000139(Golgi membrane);GO:0001077(transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0000977(RNA polymerase II regulatory region sequence-specific DNA binding);GO:0000982(transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0006990(positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response);GO:0090026(positive regulation of monocyte chemotaxis);GO:1902236(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway);GO:1902236(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)","04668(TNF signaling pathway);04024(cAMP signaling pathway);04022(cGMP - PKG signaling pathway);04151(PI3K-Akt signaling pathway);04152(AMPK signaling pathway);04911(Insulin secretion);04922(Glucagon signaling pathway);04915(Estrogen signaling pathway);04926(Relaxin signaling pathway);04918(Thyroid hormone synthesis);04916(Melanogenesis);04925(Aldosterone synthesis and secretion);04927(Cortisol synthesis and secretion);04261(Adrenergic signaling in cardiomyocytes);04962(Vasopressin-regulated water reabsorption);04725(Cholinergic synapse);04728(Dopaminergic synapse);04211(Longevity regulating pathway - mammal);05203(Viral carcinogenesis);05215(Prostate cancer);05016(Huntington's disease);05030(Cocaine addiction);05031(Amphetamine addiction);05034(Alcoholism);04931(Insulin resistance);05161(Hepatitis B);05165(Human papillomavirus infection);05165(Human papillomavirus infection)","K09048","NA","cAMP responsive element binding protein 3 [Source:HGNC Symbol;Acc:HGNC:2347]",{"v":5.35892442669469,"d":"5.36"},{"v":9.18187442984761,"d":"9.18"},{"v":0.583641659188279,"d":"0.58"},{"v":-0.776845231235186,"d":"-0.78"},{"v":0.115595490148738,"d":"0.12"},{"v":0.66786736319328,"d":"0.67"},"down","no"]
["ENSG00000154153","RETREG1","ENST00000306320;ENST00000509048;ENST00000506441;ENST00000399793","GO:0030176(integral component of endoplasmic reticulum membrane);GO:0061709(reticulophagy);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005783(endoplasmic reticulum);GO:0005794(Golgi apparatus);GO:0005789(endoplasmic reticulum membrane);GO:0016604(nuclear body);GO:0006914(autophagy);GO:0005515(protein binding);GO:0043524(negative regulation of neuron apoptotic process);GO:0005801(cis-Golgi network);GO:0019233(sensory perception of pain);GO:0019233(sensory perception of pain)","NA","NA","NA","reticulophagy regulator 1 [Source:HGNC Symbol;Acc:HGNC:25964]",{"v":1.81212667578809,"d":"1.81"},{"v":0.717903177539405,"d":"0.72"},{"v":2.52419369698169,"d":"2.52"},{"v":1.33582262147452,"d":"1.34"},{"v":0.116544211358311,"d":"0.12"},{"v":0.668689687007936,"d":"0.67"},"up","no"]
["MSTRG.13796","ATP5J2;PTCD1;ATP5J2-PTCD1","ENST00000292475;ENST00000394186;ENST00000292478;ENST00000488775;ENST00000359832;ENST00000485746;ENST00000481899;ENST00000485011;ENST00000451138;ENST00000419981;ENST00000413834;ENST00000466753;ENST00000524321;ENST00000437572;ENST00000430982;ENST00000491560","GO:0006810(transport);GO:0005634(nucleus);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005654(nucleoplasm);GO:0005739(mitochondrion);GO:0005743(mitochondrial inner membrane);GO:0006811(ion transport);GO:0015992(proton transport);GO:0070062(extracellular exosome);GO:0016887(ATPase activity);GO:0006754(ATP biosynthetic process);GO:0022857(transmembrane transporter activity);GO:0042407(cristae formation);GO:0042776(mitochondrial ATP synthesis coupled proton transport);GO:0005753(mitochondrial proton-transporting ATP synthase complex);GO:0045263(proton-transporting ATP synthase complex, coupling factor F(o));GO:0046034(ATP metabolic process);GO:0000276(mitochondrial proton-transporting ATP synthase complex, coupling factor F(o));GO:0003723(RNA binding);GO:0008033(tRNA processing);GO:0005759(mitochondrial matrix);GO:0000049(tRNA binding);GO:0042780(tRNA 3'-end processing);GO:0000276(mitochondrial proton-transporting ATP synthase complex, coupling factor F(o))","00190(Oxidative phosphorylation);00190(Oxidative phosphorylation)","K02130","NA","ATP synthase, H+ transporting, mitochondrial Fo complex subunit F2 [Source:HGNC Symbol;Acc:HGNC:848];pentatricopeptide repeat domain 1 [Source:HGNC Symbol;Acc:HGNC:22198];ATP5J2-PTCD1 readthrough [Source:HGNC Symbol;Acc:HGNC:38844]",{"v":3.07700177218369,"d":"3.08"},{"v":5.25086890038268,"d":"5.25"},{"v":0.585998590054198,"d":"0.59"},{"v":-0.771030901441653,"d":"-0.77"},{"v":0.117095933517625,"d":"0.12"},{"v":0.669539673038,"d":"0.67"},"down","no"]
["MSTRG.3039","FKBP4","ENST00000001008;ENST00000543769;ENST00000539181;ENST00000543037;ENST00000538622;ENST00000540260","GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016853(isomerase activity);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0003755(peptidyl-prolyl cis-trans isomerase activity);GO:0000413(protein peptidyl-prolyl isomerization);GO:0005739(mitochondrion);GO:0005856(cytoskeleton);GO:0042995(cell projection);GO:0005515(protein binding);GO:0005528(FK506 binding);GO:0005874(microtubule);GO:0031072(heat shock protein binding);GO:0030424(axon);GO:0044295(axonal growth cone);GO:0070062(extracellular exosome);GO:0061077(chaperone-mediated protein folding);GO:1900034(regulation of cellular response to heat);GO:0010977(negative regulation of neuron projection development);GO:0006457(protein folding);GO:0030674(protein binding, bridging);GO:0005524(ATP binding);GO:0005525(GTP binding);GO:0032767(copper-dependent protein binding);GO:0035259(glucocorticoid receptor binding);GO:0048156(tau protein binding);GO:0051219(phosphoprotein binding);GO:0006463(steroid hormone receptor complex assembly);GO:0006825(copper ion transport);GO:0007566(embryo implantation);GO:0030521(androgen receptor signaling pathway);GO:0030850(prostate gland development);GO:0031111(negative regulation of microtubule polymerization or depolymerization);GO:0031115(negative regulation of microtubule polymerization);GO:0031503(protein complex localization);GO:0046661(male sex differentiation);GO:0048608(reproductive structure development);GO:0043005(neuron projection);GO:0043025(neuronal cell body);GO:0043234(protein complex);GO:0048471(perinuclear region of cytoplasm);GO:0048471(perinuclear region of cytoplasm)","04915(Estrogen signaling pathway);04915(Estrogen signaling pathway)","K09571","EC:5.2.1.8","FK506 binding protein 4 [Source:HGNC Symbol;Acc:HGNC:3720]",{"v":3.30652405965251,"d":"3.31"},{"v":5.62591717760618,"d":"5.63"},{"v":0.587730667776988,"d":"0.59"},{"v":-0.766772914792076,"d":"-0.77"},{"v":0.118354861318128,"d":"0.12"},{"v":0.67144846335487,"d":"0.67"},"down","no"]
["MSTRG.4182","ACIN1","ENST00000473758;ENST00000555053;ENST00000457657;ENST00000557039;ENST00000605057;ENST00000262710;ENST00000556052;ENST00000555566;ENST00000555807;ENST00000555352;ENST00000553790;ENST00000553721;ENST00000554708;ENST00000555395;ENST00000553501;ENST00000554979;ENST00000357481;ENST00000397341;ENST00000557432;ENST00000338631;ENST00000554680;ENST00000557515;ENST00000555478","GO:0003676(nucleic acid binding);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0005886(plasma membrane);GO:0003723(RNA binding);GO:0006397(mRNA processing);GO:0008380(RNA splicing);GO:0005634(nucleus);GO:0016607(nuclear speck);GO:0005515(protein binding);GO:0006915(apoptotic process);GO:0030218(erythrocyte differentiation);GO:0016887(ATPase activity);GO:0019899(enzyme binding);GO:0061574(ASAP complex);GO:0097194(execution phase of apoptosis);GO:0030263(apoptotic chromosome condensation);GO:0045657(positive regulation of monocyte differentiation);GO:0005730(nucleolus);GO:0005730(nucleolus)","03040(Spliceosome);03013(RNA transport);03015(mRNA surveillance pathway);03015(mRNA surveillance pathway)","K12875","NA","apoptotic chromatin condensation inducer 1 [Source:HGNC Symbol;Acc:HGNC:17066]",{"v":14.590021670472,"d":"14.59"},{"v":5.92206986267837,"d":"5.92"},{"v":2.46366929279578,"d":"2.46"},{"v":1.30080861087691,"d":"1.30"},{"v":0.119105144918755,"d":"0.12"},{"v":0.672638332245217,"d":"0.67"},"up","no"]
["MSTRG.8086","POLR2I","ENST00000221859;ENST00000586789;ENST00000589591;ENST00000589069;ENST00000592962;ENST00000585842","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0006351(transcription, DNA-templated);GO:0006379(mRNA cleavage);GO:0005730(nucleolus);GO:0003899(DNA-directed 5'-3' RNA polymerase activity);GO:0005654(nucleoplasm);GO:0006366(transcription from RNA polymerase II promoter);GO:0006368(transcription elongation from RNA polymerase II promoter);GO:0006370(7-methylguanosine mRNA capping);GO:0050434(positive regulation of viral transcription);GO:0006367(transcription initiation from RNA polymerase II promoter);GO:0042795(snRNA transcription from RNA polymerase II promoter);GO:0000398(mRNA splicing, via spliceosome);GO:0060964(regulation of gene silencing by miRNA);GO:0006283(transcription-coupled nucleotide-excision repair);GO:0008543(fibroblast growth factor receptor signaling pathway);GO:0016070(RNA metabolic process);GO:0035019(somatic stem cell population maintenance);GO:0005665(DNA-directed RNA polymerase II, core complex);GO:0001193(maintenance of transcriptional fidelity during DNA-templated transcription elongation from RNA polymerase II promoter);GO:0001193(maintenance of transcriptional fidelity during DNA-templated transcription elongation from RNA polymerase II promoter)","00230(Purine metabolism);00240(Pyrimidine metabolism);03020(RNA polymerase);05016(Huntington's disease);05169(Epstein-Barr virus infection);05169(Epstein-Barr virus infection)","K03017","NA","RNA polymerase II subunit I [Source:HGNC Symbol;Acc:HGNC:9196]",{"v":2.5766795571316,"d":"2.58"},{"v":4.44318049251379,"d":"4.44"},{"v":0.579917822711228,"d":"0.58"},{"v":-0.786079617348247,"d":"-0.79"},{"v":0.12018801236344,"d":"0.12"},{"v":0.672638332245217,"d":"0.67"},"down","no"]
["MSTRG.1151","MGST3","ENST00000367889;ENST00000367884;ENST00000460632;ENST00000367888;ENST00000495447;ENST00000367885;ENST00000609263;ENST00000477450;ENST00000627653;ENST00000461308;ENST00000494074","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016740(transferase activity);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005515(protein binding);GO:0004602(glutathione peroxidase activity);GO:0010243(response to organonitrogen compound);GO:0098869(cellular oxidant detoxification);GO:0004364(glutathione transferase activity);GO:0043231(intracellular membrane-bounded organelle);GO:0070062(extracellular exosome);GO:0005635(nuclear envelope);GO:0006805(xenobiotic metabolic process);GO:0007165(signal transduction);GO:0031090(organelle membrane);GO:0006629(lipid metabolic process);GO:0004601(peroxidase activity);GO:1901687(glutathione derivative biosynthetic process);GO:1901687(glutathione derivative biosynthetic process)","00480(Glutathione metabolism);00980(Metabolism of xenobiotics by cytochrome P450);00982(Drug metabolism - cytochrome P450);00983(Drug metabolism - other enzymes);05200(Pathways in cancer);05204(Chemical carcinogenesis);05225(Hepatocellular carcinoma);05418(Fluid shear stress and atherosclerosis);01524(Platinum drug resistance);01524(Platinum drug resistance)","K00799","EC:2.5.1.18","microsomal glutathione S-transferase 3 [Source:HGNC Symbol;Acc:HGNC:7064]",{"v":1.44410565769554,"d":"1.44"},{"v":2.45146820740118,"d":"2.45"},{"v":0.589077864985427,"d":"0.59"},{"v":-0.763469751147933,"d":"-0.76"},{"v":0.121206626795773,"d":"0.12"},{"v":0.673157607355003,"d":"0.67"},"down","no"]
["ENSG00000148429","USP6NL","ENST00000609104;ENST00000443016;ENST00000609853;ENST00000379237;ENST00000606752","GO:0005794(Golgi apparatus);GO:0005886(plasma membrane);GO:0031410(cytoplasmic vesicle);GO:0005096(GTPase activator activity);GO:0006886(intracellular protein transport);GO:0031338(regulation of vesicle fusion);GO:0090630(activation of GTPase activity);GO:0012505(endomembrane system);GO:0005829(cytosol);GO:0043547(positive regulation of GTPase activity);GO:0032588(trans-Golgi network membrane);GO:0007030(Golgi organization);GO:0017137(Rab GTPase binding);GO:0048227(plasma membrane to endosome transport);GO:0019068(virion assembly);GO:1903358(regulation of Golgi organization);GO:0035526(retrograde transport, plasma membrane to Golgi);GO:0035526(retrograde transport, plasma membrane to Golgi)","NA","NA","NA","USP6 N-terminal like [Source:HGNC Symbol;Acc:HGNC:16858]",{"v":0.774174626390649,"d":"0.77"},{"v":0.312447867342628,"d":"0.31"},{"v":2.47777215756027,"d":"2.48"},{"v":1.30904353119502,"d":"1.31"},{"v":0.121660217216016,"d":"0.12"},{"v":0.673685457568423,"d":"0.67"},"up","no"]
["MSTRG.232","RPL11","ENST00000482370;MSTRG.232.3;ENST00000374550;ENST00000443624;ENST00000458455;ENST00000467075","GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0006412(translation);GO:0030529(intracellular ribonucleoprotein complex);GO:0005622(intracellular);GO:0003735(structural constituent of ribosome);GO:0005840(ribosome);GO:0005515(protein binding);GO:0005654(nucleoplasm);GO:0005730(nucleolus);GO:0006364(rRNA processing);GO:0000027(ribosomal large subunit assembly);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0031012(extracellular matrix);GO:0019843(rRNA binding);GO:0042273(ribosomal large subunit biogenesis);GO:0032435(negative regulation of proteasomal ubiquitin-dependent protein catabolic process);GO:0006605(protein targeting);GO:0043234(protein complex);GO:0006413(translational initiation);GO:0034504(protein localization to nucleus);GO:0000184(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay);GO:0019083(viral transcription);GO:0006614(SRP-dependent cotranslational protein targeting to membrane);GO:0010628(positive regulation of gene expression);GO:0050821(protein stabilization);GO:0022625(cytosolic large ribosomal subunit);GO:0031625(ubiquitin protein ligase binding);GO:1901796(regulation of signal transduction by p53 class mediator);GO:0008097(5S rRNA binding);GO:1990948(ubiquitin ligase inhibitor activity);GO:1904667(negative regulation of ubiquitin protein ligase activity);GO:2000059(negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process);GO:2000435(negative regulation of protein neddylation);GO:0032092(positive regulation of protein binding);GO:1901798(positive regulation of signal transduction by p53 class mediator);GO:1902255(positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator);GO:1902255(positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator)","03010(Ribosome);03010(Ribosome)","K02868","NA","ribosomal protein L11 [Source:HGNC Symbol;Acc:HGNC:10301]",{"v":264.723963739809,"d":"264.72"},{"v":444.536478060393,"d":"444.54"},{"v":0.595505603713009,"d":"0.60"},{"v":-0.747813010960978,"d":"-0.75"},{"v":0.12326967542255,"d":"0.12"},{"v":0.675963442625607,"d":"0.68"},"down","no"]
["MSTRG.13681","NSUN5P2","ENST00000602348;ENST00000388955;ENST00000457352;ENST00000444583","NA","NA","NA","NA","NOP2/Sun RNA methyltransferase family member 5 pseudogene 2 [Source:HGNC Symbol;Acc:HGNC:16609]",{"v":1.36306095031056,"d":"1.36"},{"v":2.32036777018634,"d":"2.32"},{"v":0.587433150823801,"d":"0.59"},{"v":-0.767503410805176,"d":"-0.77"},{"v":0.123769210705757,"d":"0.12"},{"v":0.67729431876979,"d":"0.68"},"down","no"]
["ENSG00000182628","SKA2","ENST00000330137;ENST00000583380;ENST00000581068;ENST00000583976;ENST00000584089;ENST00000437036;ENST00000578519;ENST00000583927;ENST00000578105","GO:0005737(cytoplasm);GO:0051301(cell division);GO:0005694(chromosome);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0007049(cell cycle);GO:0008017(microtubule binding);GO:0007059(chromosome segregation);GO:0005874(microtubule);GO:0005819(spindle);GO:0000775(chromosome, centromeric region);GO:0000776(kinetochore);GO:0000777(condensed chromosome kinetochore);GO:0005829(cytosol);GO:0000940(condensed chromosome outer kinetochore);GO:0005876(spindle microtubule);GO:0007062(sister chromatid cohesion);GO:0000278(mitotic cell cycle);GO:0031110(regulation of microtubule polymerization or depolymerization);GO:0031110(regulation of microtubule polymerization or depolymerization)","NA","NA","NA","spindle and kinetochore associated complex subunit 2 [Source:HGNC Symbol;Acc:HGNC:28006]",{"v":0.915346642630241,"d":"0.92"},{"v":1.57345684021601,"d":"1.57"},{"v":0.581742453453365,"d":"0.58"},{"v":-0.781547504230564,"d":"-0.78"},{"v":0.125091718584187,"d":"0.13"},{"v":0.678193337029954,"d":"0.68"},"down","no"]
["MSTRG.15374","PGK1","ENST00000373316;ENST00000474281;ENST00000476531;MSTRG.15374.4;ENST00000477335;ENST00000491291","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0006096(glycolytic process);GO:0005515(protein binding);GO:0045121(membrane raft);GO:0004618(phosphoglycerate kinase activity);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0030855(epithelial cell differentiation);GO:0006094(gluconeogenesis);GO:0061621(canonical glycolysis);GO:0047134(protein-disulfide reductase activity);GO:0016525(negative regulation of angiogenesis);GO:0031639(plasminogen activation);GO:0071456(cellular response to hypoxia);GO:0005615(extracellular space);GO:0005615(extracellular space)","00010(Glycolysis / Gluconeogenesis);04066(HIF-1 signaling pathway);04066(HIF-1 signaling pathway)","K00927","EC:2.7.2.3","phosphoglycerate kinase 1 [Source:HGNC Symbol;Acc:HGNC:8896]",{"v":32.4266644806258,"d":"32.43"},{"v":54.2444313760233,"d":"54.24"},{"v":0.597787895606161,"d":"0.60"},{"v":-0.742294410192806,"d":"-0.74"},{"v":0.125412790178093,"d":"0.13"},{"v":0.678675496919502,"d":"0.68"},"down","no"]
["MSTRG.272","ZNF593","ENST00000374266;ENST00000270812","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0005730(nucleolus);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0030687(preribosome, large subunit precursor);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0043023(ribosomal large subunit binding);GO:0000055(ribosomal large subunit export from nucleus);GO:1903026(negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding);GO:1903026(negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding)","NA","NA","NA","zinc finger protein 593 [Source:HGNC Symbol;Acc:HGNC:30943]",{"v":3.07594076723017,"d":"3.08"},{"v":5.2066488153446,"d":"5.21"},{"v":0.59077169909463,"d":"0.59"},{"v":-0.759327379403795,"d":"-0.76"},{"v":0.127117068967408,"d":"0.13"},{"v":0.680927000757001,"d":"0.68"},"down","no"]
["ENSG00000166575","TMEM135","ENST00000305494;ENST00000340353;ENST00000531800;ENST00000528861;ENST00000532959;ENST00000531643","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005739(mitochondrion);GO:0005777(peroxisome);GO:0005778(peroxisomal membrane);GO:0031966(mitochondrial membrane);GO:0007031(peroxisome organization);GO:0009409(response to cold);GO:0032094(response to food);GO:0090140(regulation of mitochondrial fission);GO:0005811(lipid particle);GO:0005811(lipid particle)","NA","NA","NA","transmembrane protein 135 [Source:HGNC Symbol;Acc:HGNC:26167]",{"v":0.20474460139165,"d":"0.20"},{"v":0.360325955666004,"d":"0.36"},{"v":0.568220518594651,"d":"0.57"},{"v":-0.815477166316133,"d":"-0.82"},{"v":0.127497805759817,"d":"0.13"},{"v":0.680927000757001,"d":"0.68"},"down","no"]
["MSTRG.10751","OXSM","ENST00000280701;ENST00000464688;ENST00000452098;ENST00000448177;ENST00000428266;ENST00000449808","GO:0003824(catalytic activity);GO:0008152(metabolic process);GO:0005829(cytosol);GO:0016740(transferase activity);GO:0005739(mitochondrion);GO:0016746(transferase activity, transferring acyl groups);GO:0006629(lipid metabolic process);GO:0006631(fatty acid metabolic process);GO:0006633(fatty acid biosynthetic process);GO:0016747(transferase activity, transferring acyl groups other than amino-acyl groups);GO:0004315(3-oxoacyl-[acyl-carrier-protein] synthase activity);GO:0006637(acyl-CoA metabolic process);GO:0051790(short-chain fatty acid biosynthetic process);GO:0051792(medium-chain fatty acid biosynthetic process);GO:0051792(medium-chain fatty acid biosynthetic process)","00061(Fatty acid biosynthesis);00780(Biotin metabolism);00780(Biotin metabolism)","K09458","EC:2.3.1.179","3-oxoacyl-ACP synthase, mitochondrial [Source:HGNC Symbol;Acc:HGNC:26063]",{"v":0.931643653660499,"d":"0.93"},{"v":1.58094911263073,"d":"1.58"},{"v":0.589293890750364,"d":"0.59"},{"v":-0.762940785137414,"d":"-0.76"},{"v":0.12865852232409,"d":"0.13"},{"v":0.681620173243454,"d":"0.68"},"down","no"]
["MSTRG.8890","RMND5A","ENST00000283632;ENST00000472843","GO:0005515(protein binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0004842(ubiquitin-protein transferase activity);GO:0043161(proteasome-mediated ubiquitin-dependent protein catabolic process);GO:0042787(protein ubiquitination involved in ubiquitin-dependent protein catabolic process);GO:0034657(GID complex);GO:0034657(GID complex)","NA","NA","NA","required for meiotic nuclear division 5 homolog A [Source:HGNC Symbol;Acc:HGNC:25850]",{"v":13.2334835529101,"d":"13.23"},{"v":5.49172619385656,"d":"5.49"},{"v":2.40971291826494,"d":"2.41"},{"v":1.2688612808678,"d":"1.27"},{"v":0.130314408143229,"d":"0.13"},{"v":0.684345885809614,"d":"0.68"},"up","no"]
["MSTRG.2883","SIDT2","ENST00000324225;ENST00000532062;ENST00000529484;ENST00000526813;ENST00000524988;ENST00000527654;ENST00000431081;ENST00000525339;ENST00000531255;ENST00000528397;ENST00000278951;ENST00000530948;ENST00000525065;ENST00000532960;ENST00000529441","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005765(lysosomal membrane);GO:0005764(lysosome);GO:0051033(RNA transmembrane transporter activity);GO:0033227(dsRNA transport);GO:0003725(double-stranded RNA binding);GO:0000902(cell morphogenesis);GO:0003323(type B pancreatic cell development);GO:0009749(response to glucose);GO:0042593(glucose homeostasis);GO:0044342(type B pancreatic cell proliferation);GO:0061178(regulation of insulin secretion involved in cellular response to glucose stimulus);GO:0061178(regulation of insulin secretion involved in cellular response to glucose stimulus)","NA","NA","NA","SID1 transmembrane family member 2 [Source:HGNC Symbol;Acc:HGNC:24272]",{"v":2.20801141121289,"d":"2.21"},{"v":0.911629836772983,"d":"0.91"},{"v":2.4220482065713,"d":"2.42"},{"v":1.27622757960253,"d":"1.28"},{"v":0.130484558680862,"d":"0.13"},{"v":0.684345885809614,"d":"0.68"},"up","no"]
["ENSG00000165684","SNAPC4","ENST00000298532;ENST00000637388","GO:0005634(nucleus);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0009301(snRNA transcription);GO:0019185(snRNA-activating protein complex);GO:0005654(nucleoplasm);GO:0000981(RNA polymerase II transcription factor activity, sequence-specific DNA binding);GO:0030154(cell differentiation);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0006366(transcription from RNA polymerase II promoter);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0043565(sequence-specific DNA binding);GO:0042795(snRNA transcription from RNA polymerase II promoter);GO:0044212(transcription regulatory region DNA binding);GO:0006383(transcription from RNA polymerase III promoter);GO:0001135(transcription factor activity, RNA polymerase II transcription factor recruiting);GO:0042796(snRNA transcription from RNA polymerase III promoter);GO:0042796(snRNA transcription from RNA polymerase III promoter)","NA","NA","NA","small nuclear RNA activating complex polypeptide 4 [Source:HGNC Symbol;Acc:HGNC:11137]",{"v":1.93668102993062,"d":"1.94"},{"v":0.799125221803766,"d":"0.80"},{"v":2.42350132005494,"d":"2.42"},{"v":1.2770928683249,"d":"1.28"},{"v":0.132259311126889,"d":"0.13"},{"v":0.687091293183461,"d":"0.69"},"up","no"]
["MSTRG.4710","SIVA1","ENST00000329967;ENST00000553819;ENST00000554013;ENST00000347067;ENST00000535554;ENST00000556195;ENST00000556431","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0005654(nucleoplasm);GO:0005515(protein binding);GO:0006915(apoptotic process);GO:0046718(viral entry into host cell);GO:0016032(viral process);GO:0001618(virus receptor activity);GO:0005164(tumor necrosis factor receptor binding);GO:0005175(CD27 receptor binding);GO:0097191(extrinsic apoptotic signaling pathway);GO:0051537(2 iron, 2 sulfur cluster binding);GO:0051537(2 iron, 2 sulfur cluster binding)","NA","NA","NA","SIVA1 apoptosis inducing factor [Source:HGNC Symbol;Acc:HGNC:17712]",{"v":1.91836800460637,"d":"1.92"},{"v":3.19190211620603,"d":"3.19"},{"v":0.601010912855494,"d":"0.60"},{"v":-0.734536907978244,"d":"-0.73"},{"v":0.132669639911947,"d":"0.13"},{"v":0.687091293183461,"d":"0.69"},"down","no"]
["ENSG00000183793","NPIPA5","ENST00000360151;ENST00000543801;ENST00000534094","GO:0005654(nucleoplasm);GO:0005654(nucleoplasm)","NA","NA","NA","nuclear pore complex interacting protein family member A5 [Source:HGNC Symbol;Acc:HGNC:41980]",{"v":1.52633525592105,"d":"1.53"},{"v":0.601800016447368,"d":"0.60"},{"v":2.53628317415398,"d":"2.54"},{"v":1.34271583031192,"d":"1.34"},{"v":0.134053114919926,"d":"0.13"},{"v":0.689705116746773,"d":"0.69"},"up","no"]
["ENSG00000025039","RRAGD","ENST00000369415;ENST00000492783;ENST00000359203","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005525(GTP binding);GO:0000166(nucleotide binding);GO:0005654(nucleoplasm);GO:0005813(centrosome);GO:0005515(protein binding);GO:0005764(lysosome);GO:0034448(EGO complex);GO:0071230(cellular response to amino acid stimulus);GO:0005829(cytosol);GO:0046982(protein heterodimerization activity);GO:0032008(positive regulation of TOR signaling);GO:0003924(GTPase activity);GO:0007050(cell cycle arrest);GO:0016241(regulation of macroautophagy);GO:0010506(regulation of autophagy);GO:0019003(GDP binding);GO:0034613(cellular protein localization);GO:0071233(cellular response to leucine);GO:1990253(cellular response to leucine starvation);GO:0051020(GTPase binding);GO:1904263(positive regulation of TORC1 signaling);GO:1990131(Gtr1-Gtr2 GTPase complex);GO:1990131(Gtr1-Gtr2 GTPase complex)","04150(mTOR signaling pathway);04140(Autophagy - animal);04140(Autophagy - animal)","K16186","NA","Ras related GTP binding D [Source:HGNC Symbol;Acc:HGNC:19903]",{"v":1.15352009069401,"d":"1.15"},{"v":1.90480265851735,"d":"1.90"},{"v":0.605585090684345,"d":"0.61"},{"v":-0.723598407827484,"d":"-0.72"},{"v":0.135830858434898,"d":"0.14"},{"v":0.690601727624949,"d":"0.69"},"down","no"]
["MSTRG.12279","CDC42SE2","ENST00000395246;MSTRG.12279.6;ENST00000360515;MSTRG.12279.7;ENST00000504701;ENST00000515533;ENST00000506419;ENST00000502840;ENST00000505065;ENST00000502639;MSTRG.12279.8;ENST00000511432;ENST00000503291;ENST00000506929","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005886(plasma membrane);GO:0005856(cytoskeleton);GO:0042995(cell projection);GO:0005515(protein binding);GO:0070062(extracellular exosome);GO:0001891(phagocytic cup);GO:0008360(regulation of cell shape);GO:0006909(phagocytosis);GO:0009966(regulation of signal transduction);GO:0005198(structural molecule activity);GO:0005198(structural molecule activity)","NA","NA","NA","CDC42 small effector 2 [Source:HGNC Symbol;Acc:HGNC:18547]",{"v":11.1019708572802,"d":"11.10"},{"v":18.2282398886753,"d":"18.23"},{"v":0.609053365825932,"d":"0.61"},{"v":-0.715359450927624,"d":"-0.72"},{"v":0.135899490468264,"d":"0.14"},{"v":0.690601727624949,"d":"0.69"},"down","no"]
["ENSG00000188312","CENPP","ENST00000375587;ENST00000375576;ENST00000618653;ENST00000375579","GO:0005634(nucleus);GO:0005730(nucleolus);GO:0005694(chromosome);GO:0005515(protein binding);GO:0000775(chromosome, centromeric region);GO:0034080(CENP-A containing nucleosome assembly);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0007062(sister chromatid cohesion);GO:0007062(sister chromatid cohesion)","NA","NA","NA","centromere protein P [Source:HGNC Symbol;Acc:HGNC:32933]",{"v":0.342282492546457,"d":"0.34"},{"v":0.139479107208495,"d":"0.14"},{"v":2.45400547362846,"d":"2.45"},{"v":1.29513846691762,"d":"1.30"},{"v":0.137365215040356,"d":"0.14"},{"v":0.690601727624949,"d":"0.69"},"up","no"]
["ENSG00000206053","JPT2","ENST00000248098;ENST00000382710;ENST00000562569;ENST00000566742;ENST00000561516;ENST00000566691;ENST00000566925;ENST00000569765;ENST00000567717;ENST00000565851;ENST00000569256;ENST00000562684","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0005886(plasma membrane)","NA","NA","NA","Jupiter microtubule associated homolog 2 [Source:HGNC Symbol;Acc:HGNC:14137]",{"v":0.87417666715604,"d":"0.87"},{"v":1.43682825188758,"d":"1.44"},{"v":0.608407209426473,"d":"0.61"},{"v":-0.716890846259213,"d":"-0.72"},{"v":0.137419142509059,"d":"0.14"},{"v":0.690601727624949,"d":"0.69"},"down","no"]
["MSTRG.15384","ARMCX6","ENST00000497931;ENST00000361910;ENST00000539247;ENST00000494624;ENST00000462302","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016021(integral component of membrane)","NA","NA","NA","armadillo repeat containing, X-linked 6 [Source:HGNC Symbol;Acc:HGNC:26094]",{"v":3.60661262756127,"d":"3.61"},{"v":5.93073617798313,"d":"5.93"},{"v":0.608122249806056,"d":"0.61"},{"v":-0.717566719474825,"d":"-0.72"},{"v":0.13851761426783,"d":"0.14"},{"v":0.692170849609425,"d":"0.69"},"down","no"]
["ENSG00000058453","CROCC","ENST00000375541;ENST00000494191;ENST00000467938;ENST00000466256;ENST00000477773;ENST00000465021;ENST00000492631;ENST00000445545;ENST00000498688;ENST00000465291;ENST00000486318;ENST00000497654","GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0005813(centrosome);GO:0015629(actin cytoskeleton);GO:0005856(cytoskeleton);GO:0042995(cell projection);GO:0007049(cell cycle);GO:0007098(centrosome cycle);GO:0005815(microtubule organizing center);GO:0035253(ciliary rootlet);GO:0005515(protein binding);GO:0005929(cilium);GO:0070062(extracellular exosome);GO:0030030(cell projection organization);GO:0005814(centriole);GO:0019894(kinesin binding);GO:0005198(structural molecule activity);GO:0045724(positive regulation of cilium assembly);GO:0008104(protein localization);GO:0033365(protein localization to organelle);GO:0010457(centriole-centriole cohesion);GO:1903566(positive regulation of protein localization to cilium);GO:0003779(actin binding);GO:0010669(epithelial structure maintenance);GO:0032053(ciliary basal body organization);GO:0045494(photoreceptor cell maintenance);GO:0051656(establishment of organelle localization);GO:0001917(photoreceptor inner segment);GO:0001917(photoreceptor inner segment)","NA","NA","NA","ciliary rootlet coiled-coil, rootletin [Source:HGNC Symbol;Acc:HGNC:21299]",{"v":1.91760031743885,"d":"1.92"},{"v":0.80199692886935,"d":"0.80"},{"v":2.39103199577369,"d":"2.39"},{"v":1.25763343571043,"d":"1.26"},{"v":0.139386824589638,"d":"0.14"},{"v":0.69442264863126,"d":"0.69"},"up","no"]
["MSTRG.14978","ENG","ENST00000373203;ENST00000462196;ENST00000486329;ENST00000344849","GO:0005615(extracellular space);GO:0010629(negative regulation of gene expression);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0001934(positive regulation of protein phosphorylation);GO:1905065(positive regulation of vascular smooth muscle cell differentiation);GO:0030336(negative regulation of cell migration);GO:0030513(positive regulation of BMP signaling pathway);GO:0030509(BMP signaling pathway);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0007155(cell adhesion);GO:0005515(protein binding);GO:0005114(type II transforming growth factor beta receptor binding);GO:0042803(protein homodimerization activity);GO:0050431(transforming growth factor beta binding);GO:0001300(chronological cell aging);GO:0001525(angiogenesis);GO:0001569(branching involved in blood vessel morphogenesis);GO:0001570(vasculogenesis);GO:0001947(heart looping);GO:0003148(outflow tract septum morphogenesis);GO:0003198(epithelial to mesenchymal transition involved in endocardial cushion formation);GO:0003203(endocardial cushion morphogenesis);GO:0003208(cardiac ventricle morphogenesis);GO:0003209(cardiac atrium morphogenesis);GO:0003222(ventricular trabecula myocardium morphogenesis);GO:0003273(cell migration involved in endocardial cushion formation);GO:0007507(heart development);GO:0010628(positive regulation of gene expression);GO:0017015(regulation of transforming growth factor beta receptor signaling pathway);GO:0031960(response to corticosteroid);GO:0032967(positive regulation of collagen biosynthetic process);GO:0035912(dorsal aorta morphogenesis);GO:0042493(response to drug);GO:0045766(positive regulation of angiogenesis);GO:0048745(smooth muscle tissue development);GO:0048844(artery morphogenesis);GO:0048845(venous blood vessel morphogenesis);GO:0055009(atrial cardiac muscle tissue morphogenesis);GO:0060348(bone development);GO:0070278(extracellular matrix constituent secretion);GO:0071260(cellular response to mechanical stimulus);GO:0071559(response to transforming growth factor beta);GO:0097084(vascular smooth muscle cell development);GO:1905007(positive regulation of epithelial to mesenchymal transition involved in endocardial cushion formation);GO:1905222(atrioventricular canal morphogenesis);GO:0009986(cell surface);GO:0072563(endothelial microparticle);GO:0005925(focal adhesion);GO:0009897(external side of plasma membrane);GO:0043235(receptor complex);GO:0034713(type I transforming growth factor beta receptor binding);GO:0048185(activin binding);GO:0036122(BMP binding);GO:0010862(positive regulation of pathway-restricted SMAD protein phosphorylation);GO:0004888(transmembrane signaling receptor activity);GO:0005539(glycosaminoglycan binding);GO:0006355(regulation of transcription, DNA-templated);GO:0005072(transforming growth factor beta receptor, cytoplasmic mediator activity);GO:0005534(galactose binding);GO:0022009(central nervous system vasculogenesis);GO:0031953(negative regulation of protein autophosphorylation);GO:0070022(transforming growth factor beta receptor complex);GO:0070022(transforming growth factor beta receptor complex)","NA","NA","NA","endoglin [Source:HGNC Symbol;Acc:HGNC:3349]",{"v":3.08502496442186,"d":"3.09"},{"v":1.29511893824651,"d":"1.30"},{"v":2.38203988322396,"d":"2.38"},{"v":1.25219756888957,"d":"1.25"},{"v":0.141447650193377,"d":"0.14"},{"v":0.69869483696116,"d":"0.70"},"up","no"]
["MSTRG.2929","RNF26","ENST00000311413","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0046872(metal ion binding);GO:0016740(transferase activity);GO:0016567(protein ubiquitination);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0008270(zinc ion binding);GO:0005515(protein binding);GO:0070979(protein K11-linked ubiquitination);GO:0061630(ubiquitin protein ligase activity);GO:0007032(endosome organization);GO:0050687(negative regulation of defense response to virus);GO:1905719(protein localization to perinuclear region of cytoplasm);GO:0032479(regulation of type I interferon production)","NA","NA","NA","ring finger protein 26 [Source:HGNC Symbol;Acc:HGNC:14646]",{"v":4.259876,"d":"4.26"},{"v":1.793331,"d":"1.79"},{"v":2.37539862970082,"d":"2.38"},{"v":1.24816964095275,"d":"1.25"},{"v":0.143094289322221,"d":"0.14"},{"v":0.701754215328949,"d":"0.70"},"up","no"]
["ENSG00000166037","CEP57","ENST00000325542;ENST00000538158;ENST00000538658;ENST00000535224;ENST00000540830;ENST00000536587;ENST00000325486;ENST00000537677;ENST00000541768;ENST00000541365;ENST00000538095;ENST00000544522;ENST00000541150","GO:0008017(microtubule binding);GO:0034453(microtubule anchoring);GO:0043015(gamma-tubulin binding);GO:0042802(identical protein binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005794(Golgi apparatus);GO:0042803(protein homodimerization activity);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0005874(microtubule);GO:0005813(centrosome);GO:0005815(microtubule organizing center);GO:0005829(cytosol);GO:0000086(G2/M transition of mitotic cell cycle);GO:0010389(regulation of G2/M transition of mitotic cell cycle);GO:0097711(ciliary basal body docking);GO:0000070(mitotic sister chromatid segregation);GO:0000060(protein import into nucleus, translocation);GO:0008543(fibroblast growth factor receptor signaling pathway);GO:0017134(fibroblast growth factor binding);GO:0007286(spermatid development);GO:0051260(protein homooligomerization);GO:0051260(protein homooligomerization)","NA","NA","NA","centrosomal protein 57 [Source:HGNC Symbol;Acc:HGNC:30794]",{"v":2.382534582594,"d":"2.38"},{"v":3.86898268342487,"d":"3.87"},{"v":0.615803888914011,"d":"0.62"},{"v":-0.699457116593229,"d":"-0.70"},{"v":0.143854924708199,"d":"0.14"},{"v":0.703155143484273,"d":"0.70"},"down","no"]
["MSTRG.2583","YIF1A","ENST00000376901;ENST00000485820;ENST00000494836;ENST00000359461;ENST00000484814;ENST00000431556;ENST00000534374;ENST00000376899;ENST00000496746;ENST00000471387","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0006810(transport);GO:0015031(protein transport);GO:0005794(Golgi apparatus);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005515(protein binding);GO:0000139(Golgi membrane);GO:0016192(vesicle-mediated transport);GO:0030173(integral component of Golgi membrane);GO:0006888(ER to Golgi vesicle-mediated transport);GO:0036498(IRE1-mediated unfolded protein response);GO:0005793(endoplasmic reticulum-Golgi intermediate compartment);GO:0030134(ER to Golgi transport vesicle);GO:0030134(ER to Golgi transport vesicle)","NA","NA","NA","Yip1 interacting factor homolog A, membrane trafficking protein [Source:HGNC Symbol;Acc:HGNC:16688]",{"v":3.30235293206751,"d":"3.30"},{"v":5.36930876244726,"d":"5.37"},{"v":0.615042471605291,"d":"0.62"},{"v":-0.701242056047407,"d":"-0.70"},{"v":0.145192228591238,"d":"0.15"},{"v":0.705842547282471,"d":"0.71"},"down","no"]
["MSTRG.14810","ANXA1","ENST00000491192;ENST00000495713;MSTRG.14810.1;ENST00000257497;ENST00000376911;ENST00000489109;ENST00000456643;ENST00000415424;ENST00000468639","GO:0005737(cytoplasm);GO:0005634(nucleus);GO:0016020(membrane);GO:0046872(metal ion binding);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0031514(motile cilium);GO:0005509(calcium ion binding);GO:0005886(plasma membrane);GO:0042995(cell projection);GO:0005515(protein binding);GO:0007165(signal transduction);GO:0005576(extracellular region);GO:0005615(extracellular space);GO:0030659(cytoplasmic vesicle membrane);GO:0031410(cytoplasmic vesicle);GO:0004859(phospholipase inhibitor activity);GO:0005544(calcium-dependent phospholipid binding);GO:0002376(immune system process);GO:0045087(innate immune response);GO:0005925(focal adhesion);GO:0006954(inflammatory response);GO:0002250(adaptive immune response);GO:0005768(endosome);GO:0005929(cilium);GO:0070062(extracellular exosome);GO:0001891(phagocytic cup);GO:0016323(basolateral plasma membrane);GO:0042102(positive regulation of T cell proliferation);GO:0005769(early endosome);GO:0010008(endosome membrane);GO:0031901(early endosome membrane);GO:0019898(extrinsic component of membrane);GO:0008360(regulation of cell shape);GO:0009986(cell surface);GO:0098641(cadherin binding involved in cell-cell adhesion);GO:0098609(cell-cell adhesion);GO:0005913(cell-cell adherens junction);GO:0016328(lateral plasma membrane);GO:0043066(negative regulation of apoptotic process);GO:0016324(apical plasma membrane);GO:0007166(cell surface receptor signaling pathway);GO:0005102(receptor binding);GO:0030674(protein binding, bridging);GO:0006909(phagocytosis);GO:0031982(vesicle);GO:0031232(extrinsic component of external side of plasma membrane);GO:0030216(keratinocyte differentiation);GO:0005198(structural molecule activity);GO:0031532(actin cytoskeleton reorganization);GO:0032743(positive regulation of interleukin-2 production);GO:0050727(regulation of inflammatory response);GO:0045627(positive regulation of T-helper 1 cell differentiation);GO:0045629(negative regulation of T-helper 2 cell differentiation);GO:0001533(cornified envelope);GO:0005543(phospholipid binding);GO:0018149(peptide cross-linking);GO:0048306(calcium-dependent protein binding);GO:0019834(phospholipase A2 inhibitor activity);GO:0000733(DNA strand renaturation);GO:0001780(neutrophil homeostasis);GO:0002548(monocyte chemotaxis);GO:0002685(regulation of leukocyte migration);GO:0007187(G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger);GO:0031340(positive regulation of vesicle fusion);GO:0032652(regulation of interleukin-1 production);GO:0045920(negative regulation of exocytosis);GO:0046632(alpha-beta T cell differentiation);GO:0046883(regulation of hormone secretion);GO:0071385(cellular response to glucocorticoid stimulus);GO:0071621(granulocyte chemotaxis);GO:0090303(positive regulation of wound healing);GO:0097350(neutrophil clearance);GO:2000483(negative regulation of interleukin-8 secretion);GO:0031313(extrinsic component of endosome membrane);GO:0043086(negative regulation of catalytic activity);GO:0003697(single-stranded DNA binding);GO:0003727(single-stranded RNA binding);GO:0004386(helicase activity);GO:0033676(double-stranded DNA-dependent ATPase activity);GO:0036310(annealing helicase activity);GO:0042803(protein homodimerization activity);GO:0009725(response to hormone);GO:0010165(response to X-ray);GO:0014070(response to organic cyclic compound);GO:0014839(myoblast migration involved in skeletal muscle regeneration);GO:0030073(insulin secretion);GO:0030850(prostate gland development);GO:0031018(endocrine pancreas development);GO:0031394(positive regulation of prostaglandin biosynthetic process);GO:0031960(response to corticosteroid);GO:0032355(response to estradiol);GO:0032508(DNA duplex unwinding);GO:0033031(positive regulation of neutrophil apoptotic process);GO:0036292(DNA rewinding);GO:0042063(gliogenesis);GO:0042127(regulation of cell proliferation);GO:0042493(response to drug);GO:0043065(positive regulation of apoptotic process);GO:0043434(response to peptide hormone);GO:0044849(estrous cycle);GO:0050482(arachidonic acid secretion);GO:0050709(negative regulation of protein secretion);GO:0051384(response to glucocorticoid);GO:0070301(cellular response to hydrogen peroxide);GO:0070365(hepatocyte differentiation);GO:0070459(prolactin secretion);GO:0070555(response to interleukin-1);GO:1900087(positive regulation of G1/S transition of mitotic cell cycle);GO:1900138(negative regulation of phospholipase A2 activity);GO:0031966(mitochondrial membrane);GO:0042383(sarcolemma);GO:0042629(mast cell granule);GO:0043234(protein complex);GO:0043234(protein complex)","NA","NA","NA","annexin A1 [Source:HGNC Symbol;Acc:HGNC:533]",{"v":43.1636050213584,"d":"43.16"},{"v":69.6074426943614,"d":"69.61"},{"v":0.620100428209739,"d":"0.62"},{"v":-0.689426209150863,"d":"-0.69"},{"v":0.145930475921109,"d":"0.15"},{"v":0.706114299399838,"d":"0.71"},"down","no"]
["MSTRG.10161","PI4KA","ENST00000255882;ENST00000477245;ENST00000489966;ENST00000484220;ENST00000492581;ENST00000485123;ENST00000462210;ENST00000485963;ENST00000494113;ENST00000466772;ENST00000466162;ENST00000399213;ENST00000475414;ENST00000477368;ENST00000466394;ENST00000485950;MSTRG.10161.14;ENST00000449120","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0046854(phosphatidylinositol phosphorylation);GO:0048015(phosphatidylinositol-mediated signaling);GO:0005925(focal adhesion);GO:0005829(cytosol);GO:0045296(cadherin binding);GO:0070062(extracellular exosome);GO:0030660(Golgi-associated vesicle membrane);GO:0004430(1-phosphatidylinositol 4-kinase activity);GO:0007165(signal transduction);GO:0006661(phosphatidylinositol biosynthetic process);GO:0039694(viral RNA genome replication);GO:0030036(actin cytoskeleton organization);GO:0044803(multi-organism membrane organization);GO:0046786(viral replication complex formation and maintenance);GO:0019034(viral replication complex);GO:0005622(intracellular);GO:0005622(intracellular)","00562(Inositol phosphate metabolism);04070(Phosphatidylinositol signaling system);04070(Phosphatidylinositol signaling system)","K00888","EC:2.7.1.67","phosphatidylinositol 4-kinase alpha [Source:HGNC Symbol;Acc:HGNC:8983]",{"v":7.86811888077496,"d":"7.87"},{"v":3.362063000263,"d":"3.36"},{"v":2.34026515272304,"d":"2.34"},{"v":1.22667199683738,"d":"1.23"},{"v":0.147602053922508,"d":"0.15"},{"v":0.706114299399838,"d":"0.71"},"up","no"]
["MSTRG.10679","LSM3","ENST00000306024","GO:0003723(RNA binding);GO:0006397(mRNA processing);GO:0008380(RNA splicing);GO:0005634(nucleus);GO:0030529(intracellular ribonucleoprotein complex);GO:0005515(protein binding);GO:0005681(spliceosomal complex);GO:0000398(mRNA splicing, via spliceosome);GO:0000956(nuclear-transcribed mRNA catabolic process);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0033962(cytoplasmic mRNA processing body assembly);GO:0000932(P-body);GO:0046540(U4/U6 x U5 tri-snRNP complex);GO:0043928(exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay);GO:1990726(Lsm1-7-Pat1 complex);GO:0071013(catalytic step 2 spliceosome);GO:0071011(precatalytic spliceosome);GO:0005688(U6 snRNP)","03040(Spliceosome);03018(RNA degradation)","K12622","NA","LSM3 homolog, U6 small nuclear RNA and mRNA degradation associated [Source:HGNC Symbol;Acc:HGNC:17874]",{"v":2.782919,"d":"2.78"},{"v":4.486765,"d":"4.49"},{"v":0.620250670583371,"d":"0.62"},{"v":-0.689076705000561,"d":"-0.69"},{"v":0.148239285513568,"d":"0.15"},{"v":0.706114299399838,"d":"0.71"},"down","no"]
["ENSG00000132361","CLUH","ENST00000571566;ENST00000574210;ENST00000575624;ENST00000435359;ENST00000574166;ENST00000574426;ENST00000575014;ENST00000571539;ENST00000572129;ENST00000570628;ENST00000573641;ENST00000576309;ENST00000572014","GO:0003723(RNA binding);GO:0005737(cytoplasm);GO:0003729(mRNA binding);GO:0048312(intracellular distribution of mitochondria);GO:0007005(mitochondrion organization);GO:0007005(mitochondrion organization)","NA","NA","NA","clustered mitochondria homolog [Source:HGNC Symbol;Acc:HGNC:29094]",{"v":2.73783204782609,"d":"2.74"},{"v":1.16502081724638,"d":"1.17"},{"v":2.35002843494005,"d":"2.35"},{"v":1.23267821325786,"d":"1.23"},{"v":0.149104807918129,"d":"0.15"},{"v":0.706114299399838,"d":"0.71"},"up","no"]
["MSTRG.5167","RPS27L","ENST00000330964;ENST00000439025;ENST00000482846;ENST00000462430;ENST00000559763;ENST00000455271","GO:0003723(RNA binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0030529(intracellular ribonucleoprotein complex);GO:0005622(intracellular);GO:0003735(structural constituent of ribosome);GO:0006412(translation);GO:0005840(ribosome);GO:0005515(protein binding);GO:0006281(DNA repair);GO:0045727(positive regulation of translation);GO:0000028(ribosomal small subunit assembly);GO:0008656(cysteine-type endopeptidase activator activity involved in apoptotic process);GO:0006919(activation of cysteine-type endopeptidase activity involved in apoptotic process);GO:0042771(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator);GO:0008494(translation activator activity);GO:0031571(mitotic G1 DNA damage checkpoint);GO:0022627(cytosolic small ribosomal subunit);GO:0006978(DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator);GO:0006978(DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)","03010(Ribosome);03010(Ribosome)","K02978","NA","ribosomal protein S27 like [Source:HGNC Symbol;Acc:HGNC:18476]",{"v":1.0069999868522,"d":"1.01"},{"v":1.62360753599211,"d":"1.62"},{"v":0.620223769925328,"d":"0.62"},{"v":-0.689139276940286,"d":"-0.69"},{"v":0.149813486758054,"d":"0.15"},{"v":0.706114299399838,"d":"0.71"},"down","no"]
["MSTRG.14253","DPYSL2","ENST00000311151;ENST00000523093;ENST00000523027;ENST00000521983;ENST00000474808;ENST00000521913","GO:0005737(cytoplasm);GO:0016787(hydrolase activity);GO:0016810(hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds);GO:0008017(microtubule binding);GO:0007411(axon guidance);GO:0007420(brain development);GO:0007010(cytoskeleton organization);GO:0019901(protein kinase binding);GO:0001975(response to amphetamine);GO:0010975(regulation of neuron projection development);GO:0014049(positive regulation of glutamate secretion);GO:0021510(spinal cord development);GO:0021772(olfactory bulb development);GO:0030516(regulation of axon extension);GO:0042220(response to cocaine);GO:0042493(response to drug);GO:0045664(regulation of neuron differentiation);GO:0048489(synaptic vesicle transport);GO:0005739(mitochondrion);GO:0005829(cytosol);GO:0030424(axon);GO:0030425(dendrite);GO:0030426(growth cone);GO:0043005(neuron projection);GO:0043025(neuronal cell body);GO:0043195(terminal bouton);GO:0043209(myelin sheath);GO:0043234(protein complex);GO:0016020(membrane);GO:0005886(plasma membrane);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0007275(multicellular organism development);GO:0007399(nervous system development);GO:0030154(cell differentiation);GO:0005874(microtubule);GO:0042802(identical protein binding);GO:0006897(endocytosis);GO:0070062(extracellular exosome);GO:0006139(nucleobase-containing compound metabolic process);GO:0007165(signal transduction);GO:0004157(dihydropyrimidinase activity);GO:0004157(dihydropyrimidinase activity)","04360(Axon guidance);04360(Axon guidance)","K07528","NA","dihydropyrimidinase like 2 [Source:HGNC Symbol;Acc:HGNC:3014]",{"v":7.27613692758385,"d":"7.28"},{"v":3.1227524329911,"d":"3.12"},{"v":2.33003963129234,"d":"2.33"},{"v":1.2203544936704,"d":"1.22"},{"v":0.15009017883218,"d":"0.15"},{"v":0.706652206387887,"d":"0.71"},"up","no"]
["MSTRG.13719","GTF2IP1","ENST00000622829;ENST00000616377;ENST00000621948;ENST00000618412;ENST00000611799;ENST00000622399;ENST00000619312;ENST00000620866;ENST00000615592","NA","NA","NA","NA","general transcription factor IIi pseudogene 1 [Source:HGNC Symbol;Acc:HGNC:4660]",{"v":10.118012127868,"d":"10.12"},{"v":4.35356305836576,"d":"4.35"},{"v":2.32407616295469,"d":"2.32"},{"v":1.21665734848279,"d":"1.22"},{"v":0.152138206410707,"d":"0.15"},{"v":0.709172437383877,"d":"0.71"},"up","no"]
["ENSG00000271699","SNX29P2","ENST00000507381;ENST00000509141;ENST00000502626;ENST00000603801","NA","NA","NA","NA","sorting nexin 29 pseudogene 2 [Source:HGNC Symbol;Acc:HGNC:31914]",{"v":0.680243166114529,"d":"0.68"},{"v":1.1241722569806,"d":"1.12"},{"v":0.60510581175663,"d":"0.61"},{"v":-0.724740653741685,"d":"-0.72"},{"v":0.152702749827198,"d":"0.15"},{"v":0.709172437383877,"d":"0.71"},"down","no"]
["ENSG00000168672","FAM84B","ENST00000304916;ENST00000517458","GO:0005737(cytoplasm);GO:0005515(protein binding);GO:0005886(plasma membrane);GO:0005886(plasma membrane)","NA","NA","NA","family with sequence similarity 84 member B [Source:HGNC Symbol;Acc:HGNC:24166]",{"v":1.96386135973353,"d":"1.96"},{"v":0.838382047372317,"d":"0.84"},{"v":2.34244204761865,"d":"2.34"},{"v":1.22801335582581,"d":"1.23"},{"v":0.153294582696698,"d":"0.15"},{"v":0.709172437383877,"d":"0.71"},"up","no"]
["ENSG00000078674","PCM1","ENST00000519253;ENST00000325083;ENST00000327578;ENST00000519802;ENST00000523896;ENST00000518985;ENST00000522777;ENST00000522275;ENST00000521338;ENST00000518936;ENST00000517545;ENST00000522998;ENST00000518537;ENST00000518762;ENST00000524226;ENST00000524203;ENST00000518930;ENST00000523540;ENST00000524356;ENST00000517730;ENST00000517836","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005829(cytosol);GO:0031965(nuclear membrane);GO:0005813(centrosome);GO:0005856(cytoskeleton);GO:0042995(cell projection);GO:0005515(protein binding);GO:0060271(cilium assembly);GO:0005815(microtubule organizing center);GO:0034454(microtubule anchoring at centrosome);GO:0030030(cell projection organization);GO:0071539(protein localization to centrosome);GO:0000086(G2/M transition of mitotic cell cycle);GO:0010389(regulation of G2/M transition of mitotic cell cycle);GO:0097711(ciliary basal body docking);GO:0043234(protein complex);GO:0035869(ciliary transition zone);GO:0050768(negative regulation of neurogenesis);GO:0042802(identical protein binding);GO:0090316(positive regulation of intracellular protein transport);GO:0034451(centriolar satellite);GO:0000242(pericentriolar material);GO:0001764(neuron migration);GO:0007098(centrosome cycle);GO:0022027(interkinetic nuclear migration);GO:0031122(cytoplasmic microtubule organization);GO:0034453(microtubule anchoring);GO:0035176(social behavior);GO:0035735(intraciliary transport involved in cilium assembly);GO:0097150(neuronal stem cell population maintenance);GO:1905515(non-motile cilium assembly);GO:0005814(centriole);GO:0036064(ciliary basal body);GO:0045177(apical part of cell);GO:0045177(apical part of cell)","NA","NA","NA","pericentriolar material 1 [Source:HGNC Symbol;Acc:HGNC:8727]",{"v":5.67256310086535,"d":"5.67"},{"v":2.44482658013153,"d":"2.44"},{"v":2.3202312781466,"d":"2.32"},{"v":1.21426861880327,"d":"1.21"},{"v":0.15385155396931,"d":"0.15"},{"v":0.709517489041572,"d":"0.71"},"up","no"]
["ENSG00000180182","MED14","ENST00000324817;ENST00000433003;ENST00000463072;ENST00000495865;ENST00000492219;ENST00000416199;ENST00000482034","GO:0005634(nucleus);GO:0016020(membrane);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0001104(RNA polymerase II transcription cofactor activity);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0016592(mediator complex);GO:0005515(protein binding);GO:0030374(ligand-dependent nuclear receptor transcription coactivator activity);GO:0045893(positive regulation of transcription, DNA-templated);GO:0006367(transcription initiation from RNA polymerase II promoter);GO:0005654(nucleoplasm);GO:0004872(receptor activity);GO:0003713(transcription coactivator activity);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0003712(transcription cofactor activity);GO:0030518(intracellular steroid hormone receptor signaling pathway);GO:0030521(androgen receptor signaling pathway);GO:0042809(vitamin D receptor binding);GO:0019827(stem cell population maintenance);GO:0070847(core mediator complex);GO:0070847(core mediator complex)","04919(Thyroid hormone signaling pathway);04919(Thyroid hormone signaling pathway)","K15156","NA","mediator complex subunit 14 [Source:HGNC Symbol;Acc:HGNC:2370]",{"v":3.92017718755178,"d":"3.92"},{"v":1.69679039177713,"d":"1.70"},{"v":2.31034853011278,"d":"2.31"},{"v":1.20811050737141,"d":"1.21"},{"v":0.155212217487228,"d":"0.16"},{"v":0.711598689964143,"d":"0.71"},"up","no"]
["MSTRG.9586","PCNA","ENST00000379143;ENST00000379160","GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0003677(DNA binding);GO:0006275(regulation of DNA replication);GO:0005515(protein binding);GO:0006281(DNA repair);GO:0006974(cellular response to DNA damage stimulus);GO:0016604(nuclear body);GO:0006260(DNA replication);GO:0042802(identical protein binding);GO:0016567(protein ubiquitination);GO:0006977(DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest);GO:0070062(extracellular exosome);GO:0003682(chromatin binding);GO:0000784(nuclear chromosome, telomeric region);GO:0030855(epithelial cell differentiation);GO:0030971(receptor tyrosine kinase binding);GO:0008283(cell proliferation);GO:0070182(DNA polymerase binding);GO:0019899(enzyme binding);GO:0019985(translesion synthesis);GO:0045740(positive regulation of DNA replication);GO:0005813(centrosome);GO:0016925(protein sumoylation);GO:0006283(transcription-coupled nucleotide-excision repair);GO:0045739(positive regulation of DNA repair);GO:0003684(damaged DNA binding);GO:0043596(nuclear replication fork);GO:0042276(error-prone translesion synthesis);GO:0000083(regulation of transcription involved in G1/S transition of mitotic cell cycle);GO:0042769(DNA damage response, detection of DNA damage);GO:0035035(histone acetyltransferase binding);GO:0034644(cellular response to UV);GO:0006296(nucleotide-excision repair, DNA incision, 5'-to lesion);GO:0033683(nucleotide-excision repair, DNA incision);GO:0032201(telomere maintenance via semi-conservative replication);GO:0006297(nucleotide-excision repair, DNA gap filling);GO:0070987(error-free translesion synthesis);GO:0000701(purine-specific mismatch base pair DNA N-glycosylase activity);GO:0030337(DNA polymerase processivity factor activity);GO:0032139(dinucleotide insertion or deletion binding);GO:0032405(MutLalpha complex binding);GO:0000723(telomere maintenance);GO:0006266(DNA ligation);GO:0006272(leading strand elongation);GO:0006298(mismatch repair);GO:0031297(replication fork processing);GO:0032077(positive regulation of deoxyribonuclease activity);GO:1902990(mitotic telomere maintenance via semi-conservative replication);GO:0005657(replication fork);GO:0005663(DNA replication factor C complex);GO:0030894(replisome);GO:0043626(PCNA complex);GO:0070557(PCNA-p21 complex);GO:0030331(estrogen receptor binding);GO:0006979(response to oxidative stress);GO:0007507(heart development);GO:0032355(response to estradiol);GO:0033993(response to lipid);GO:0044849(estrous cycle);GO:0046686(response to cadmium ion);GO:0070301(cellular response to hydrogen peroxide);GO:0071548(response to dexamethasone);GO:0097421(liver regeneration);GO:1902065(response to L-glutamate);GO:1902065(response to L-glutamate)","03030(DNA replication);03410(Base excision repair);03420(Nucleotide excision repair);03430(Mismatch repair);04110(Cell cycle);04530(Tight junction);05166(HTLV-I infection);05161(Hepatitis B);05161(Hepatitis B)","K04802","NA","proliferating cell nuclear antigen [Source:HGNC Symbol;Acc:HGNC:8729]",{"v":11.2800145452073,"d":"11.28"},{"v":17.9171624908226,"d":"17.92"},{"v":0.629564784657452,"d":"0.63"},{"v":-0.667573250390352,"d":"-0.67"},{"v":0.157065823429114,"d":"0.16"},{"v":0.716125735630245,"d":"0.72"},"down","no"]
["MSTRG.14176","DEFA1B","ENST00000382689","GO:0005615(extracellular space);GO:0005576(extracellular region);GO:0006952(defense response);GO:0042742(defense response to bacterium);GO:0051607(defense response to virus);GO:0070062(extracellular exosome);GO:0031012(extracellular matrix);GO:0002227(innate immune response in mucosa);GO:0019731(antibacterial humoral response);GO:0050830(defense response to Gram-positive bacterium);GO:0061844(antimicrobial humoral immune response mediated by antimicrobial peptide);GO:0043312(neutrophil degranulation);GO:0006935(chemotaxis);GO:0006955(immune response);GO:0019730(antimicrobial humoral response);GO:0010818(T cell chemotaxis);GO:0005796(Golgi lumen);GO:0035578(azurophil granule lumen);GO:0030520(intracellular estrogen receptor signaling pathway);GO:0031640(killing of cells of other organism);GO:0042832(defense response to protozoan);GO:0050832(defense response to fungus);GO:0044657(pore formation in membrane of other organism during symbiotic interaction);GO:0051852(disruption by host of symbiont cells)","NA","NA","NA","defensin alpha 1B [Source:HGNC Symbol;Acc:HGNC:33596]",{"v":11.630189,"d":"11.63"},{"v":18.509819,"d":"18.51"},{"v":0.62832537692562,"d":"0.63"},{"v":-0.670416245783123,"d":"-0.67"},{"v":0.157880924941365,"d":"0.16"},{"v":0.717039961417315,"d":"0.72"},"down","no"]
["ENSG00000169136","ATF5","ENST00000595125;ENST00000597227;ENST00000600336;ENST00000423777","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0006355(regulation of transcription, DNA-templated);GO:0006366(transcription from RNA polymerase II promoter);GO:0006351(transcription, DNA-templated);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0045893(positive regulation of transcription, DNA-templated);GO:0005813(centrosome);GO:0005815(microtubule organizing center);GO:0045444(fat cell differentiation);GO:0008285(negative regulation of cell proliferation);GO:0003682(chromatin binding);GO:0001228(transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0043565(sequence-specific DNA binding);GO:0043066(negative regulation of apoptotic process);GO:0044212(transcription regulatory region DNA binding);GO:0045892(negative regulation of transcription, DNA-templated);GO:0003714(transcription corepressor activity);GO:0015631(tubulin binding);GO:0000977(RNA polymerase II regulatory region sequence-specific DNA binding);GO:0046605(regulation of centrosome cycle);GO:0019900(kinase binding);GO:1902750(negative regulation of cell cycle G2/M phase transition);GO:0021930(cerebellar granule cell precursor proliferation);GO:0007623(circadian rhythm);GO:0009791(post-embryonic development);GO:0010468(regulation of gene expression);GO:0021889(olfactory bulb interneuron differentiation);GO:0021891(olfactory bulb interneuron development);GO:0021988(olfactory lobe development);GO:0035264(multicellular organism growth);GO:0005667(transcription factor complex);GO:0005667(transcription factor complex)","NA","NA","NA","activating transcription factor 5 [Source:HGNC Symbol;Acc:HGNC:790]",{"v":1.21557139065674,"d":"1.22"},{"v":0.51329045971564,"d":"0.51"},{"v":2.36819400721019,"d":"2.37"},{"v":1.24378727428401,"d":"1.24"},{"v":0.159308640181869,"d":"0.16"},{"v":0.717906889656902,"d":"0.72"},"up","no"]
["MSTRG.8398","VSTM1","ENST00000338372;ENST00000376626;ENST00000425006;ENST00000366170;ENST00000419106;ENST00000447872","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005576(extracellular region);GO:0005125(cytokine activity);GO:0005615(extracellular space);GO:0002376(immune system process);GO:0002376(immune system process)","NA","NA","NA","V-set and transmembrane domain containing 1 [Source:HGNC Symbol;Acc:HGNC:29455]",{"v":4.03045176237624,"d":"4.03"},{"v":6.42084828892889,"d":"6.42"},{"v":0.627713283512043,"d":"0.63"},{"v":-0.671822355690478,"d":"-0.67"},{"v":0.160998874653475,"d":"0.16"},{"v":0.720471571729295,"d":"0.72"},"down","no"]
["ENSG00000138738","PRDM5","ENST00000394435;ENST00000512845;ENST00000264808;ENST00000505484","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0005730(nucleolus);GO:0008168(methyltransferase activity);GO:0016740(transferase activity);GO:0032259(methylation);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0016569(covalent chromatin modification);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0016604(nuclear body);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:0001078(transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0043565(sequence-specific DNA binding);GO:0044212(transcription regulatory region DNA binding);GO:0045892(negative regulation of transcription, DNA-templated);GO:0070491(repressing transcription factor binding);GO:0000278(mitotic cell cycle);GO:0016575(histone deacetylation);GO:0051567(histone H3-K9 methylation);GO:1990830(cellular response to leukemia inhibitory factor);GO:1990830(cellular response to leukemia inhibitory factor)","NA","NA","NA","PR/SET domain 5 [Source:HGNC Symbol;Acc:HGNC:9349]",{"v":0.222147965325208,"d":"0.22"},{"v":0.359484622675213,"d":"0.36"},{"v":0.617962358645627,"d":"0.62"},{"v":-0.694409131594551,"d":"-0.69"},{"v":0.161552218804792,"d":"0.16"},{"v":0.721301775078836,"d":"0.72"},"down","no"]
["ENSG00000100678","SLC8A3","ENST00000216568;ENST00000533541;ENST00000381269;ENST00000356921","GO:0006810(transport);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0055085(transmembrane transport);GO:0046872(metal ion binding);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005739(mitochondrion);GO:0006811(ion transport);GO:0005886(plasma membrane);GO:0042995(cell projection);GO:0015297(antiporter activity);GO:0006814(sodium ion transport);GO:0006816(calcium ion transport);GO:0048471(perinuclear region of cytoplasm);GO:0030054(cell junction);GO:0005741(mitochondrial outer membrane);GO:0070588(calcium ion transmembrane transport);GO:0007154(cell communication);GO:0030425(dendrite);GO:0005516(calmodulin binding);GO:0005887(integral component of plasma membrane);GO:0060078(regulation of postsynaptic membrane potential);GO:0043204(perikaryon);GO:0042383(sarcolemma);GO:0043197(dendritic spine);GO:0005432(calcium:sodium antiporter activity);GO:1903779(regulation of cardiac conduction);GO:0035725(sodium ion transmembrane transport);GO:0031226(intrinsic component of plasma membrane);GO:0007612(learning);GO:0007613(memory);GO:0031594(neuromuscular junction);GO:0071456(cellular response to hypoxia);GO:0060291(long-term synaptic potentiation);GO:0042552(myelination);GO:0006874(cellular calcium ion homeostasis);GO:0006851(mitochondrial calcium ion transmembrane transport);GO:0051560(mitochondrial calcium ion homeostasis);GO:0016528(sarcoplasm);GO:0048709(oligodendrocyte differentiation);GO:0014819(regulation of skeletal muscle contraction);GO:0015368(calcium:cation antiporter activity);GO:0099580(ion antiporter activity involved in regulation of postsynaptic membrane potential);GO:0002244(hematopoietic progenitor cell differentiation);GO:0021537(telencephalon development);GO:0030001(metal ion transport);GO:0060402(calcium ion transport into cytosol);GO:0071320(cellular response to cAMP);GO:0098703(calcium ion import across plasma membrane);GO:1990034(calcium ion export from cell);GO:0005874(microtubule);GO:0043025(neuronal cell body);GO:0043025(neuronal cell body)","04371(Apelin signaling pathway);04020(Calcium signaling pathway);04022(cGMP - PKG signaling pathway);04974(Protein digestion and absorption);04740(Olfactory transduction);04740(Olfactory transduction)","K05849","NA","solute carrier family 8 member A3 [Source:HGNC Symbol;Acc:HGNC:11070]",{"v":0.228511108479394,"d":"0.23"},{"v":0.096371833728091,"d":"0.10"},{"v":2.37113998602671,"d":"2.37"},{"v":1.2455808383513,"d":"1.25"},{"v":0.163638807806294,"d":"0.16"},{"v":0.725042913031092,"d":"0.73"},"up","no"]
["ENSG00000155657","TTN","ENST00000589042;ENST00000634225;ENST00000412264;ENST00000342992;ENST00000360870","GO:0003300(cardiac muscle hypertrophy);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0018108(peptidyl-tyrosine phosphorylation);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0042802(identical protein binding);GO:0005516(calmodulin binding);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0005859(muscle myosin complex);GO:0031430(M band);GO:0019899(enzyme binding);GO:0002576(platelet degranulation);GO:0002020(protease binding);GO:0030018(Z disc);GO:0019901(protein kinase binding);GO:0005509(calcium ion binding);GO:0060048(cardiac muscle contraction);GO:0008307(structural constituent of muscle);GO:0006941(striated muscle contraction);GO:0030049(muscle filament sliding);GO:0030240(skeletal muscle thin filament assembly);GO:0030241(skeletal muscle myosin thick filament assembly);GO:0035995(detection of muscle stretch);GO:0045214(sarcomere organization);GO:0048739(cardiac muscle fiber development);GO:0048769(sarcomerogenesis);GO:0055003(cardiac myofibril assembly);GO:0055008(cardiac muscle tissue morphogenesis);GO:0031674(I band);GO:0042805(actinin binding);GO:0031433(telethonin binding);GO:0004713(protein tyrosine kinase activity);GO:0010628(positive regulation of gene expression);GO:0051592(response to calcium ion);GO:0050790(regulation of catalytic activity);GO:0051015(actin filament binding);GO:0006936(muscle contraction);GO:0043621(protein self-association);GO:0010737(protein kinase A signaling);GO:0050714(positive regulation of protein secretion);GO:0051371(muscle alpha-actinin binding);GO:0097493(structural molecule activity conferring elasticity);GO:0007076(mitotic chromosome condensation);GO:0045859(regulation of protein kinase activity);GO:0000794(condensed nuclear chromosome);GO:0000794(condensed nuclear chromosome)","05410(Hypertrophic cardiomyopathy (HCM));05414(Dilated cardiomyopathy (DCM));05414(Dilated cardiomyopathy (DCM))","K12567","EC:2.7.11.1","titin [Source:HGNC Symbol;Acc:HGNC:12403]",{"v":0.131967141036848,"d":"0.13"},{"v":0.0575575419076116,"d":"0.06"},{"v":2.29278625638105,"d":"2.29"},{"v":1.19710186681042,"d":"1.20"},{"v":0.164189067690065,"d":"0.16"},{"v":0.725321851488525,"d":"0.73"},"up","no"]
["ENSG00000181192","DHTKD1","ENST00000263035;ENST00000448829;ENST00000479283","GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0006099(tricarboxylic acid cycle);GO:0005739(mitochondrion);GO:0006096(glycolytic process);GO:0008152(metabolic process);GO:0016624(oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor);GO:0004591(oxoglutarate dehydrogenase (succinyl-transferring) activity);GO:0030976(thiamine pyrophosphate binding);GO:0005759(mitochondrial matrix);GO:0034641(cellular nitrogen compound metabolic process);GO:0006091(generation of precursor metabolites and energy);GO:0045252(oxoglutarate dehydrogenase complex);GO:0002244(hematopoietic progenitor cell differentiation);GO:0002244(hematopoietic progenitor cell differentiation)","NA","NA","NA","dehydrogenase E1 and transketolase domain containing 1 [Source:HGNC Symbol;Acc:HGNC:23537]",{"v":4.5078015135391,"d":"4.51"},{"v":1.97688527362242,"d":"1.98"},{"v":2.28025448602744,"d":"2.28"},{"v":1.18919484423278,"d":"1.19"},{"v":0.165200748918208,"d":"0.17"},{"v":0.725321851488525,"d":"0.73"},"up","no"]
["MSTRG.913","RPRD2","ENST00000369068;ENST00000401000;ENST00000492220;ENST00000369067","GO:0005654(nucleoplasm);GO:0042795(snRNA transcription from RNA polymerase II promoter);GO:0016591(DNA-directed RNA polymerase II, holoenzyme);GO:0016591(DNA-directed RNA polymerase II, holoenzyme)","NA","NA","NA","regulation of nuclear pre-mRNA domain containing 2 [Source:HGNC Symbol;Acc:HGNC:29039]",{"v":1.81312907850767,"d":"1.81"},{"v":0.795836225680934,"d":"0.80"},{"v":2.2782690960773,"d":"2.28"},{"v":1.18793815997314,"d":"1.19"},{"v":0.165994488318585,"d":"0.17"},{"v":0.72613613168358,"d":"0.73"},"up","no"]
["MSTRG.14092","AC244196.5","ENST00000617347","NA","NA","NA","NA",null,{"v":7.185633,"d":"7.19"},{"v":11.366872,"d":"11.37"},{"v":0.63215570651275,"d":"0.63"},{"v":-0.66164814194971,"d":"-0.66"},{"v":0.166844893369499,"d":"0.17"},{"v":0.726225542241376,"d":"0.73"},"down","no"]
["MSTRG.9446","ZFAND2B","ENST00000289528;ENST00000409217;ENST00000444522;ENST00000468301;ENST00000448496;ENST00000486734;ENST00000489197;ENST00000409594;ENST00000475533;ENST00000409412;ENST00000464902;ENST00000436556;ENST00000409336;ENST00000422255;ENST00000425849;ENST00000621130;ENST00000409206;ENST00000409319;ENST00000409097","GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0005783(endoplasmic reticulum);GO:0005515(protein binding);GO:0006616(SRP-dependent cotranslational protein targeting to membrane, translocation);GO:0006616(SRP-dependent cotranslational protein targeting to membrane, translocation)","NA","NA","NA","zinc finger AN1-type containing 2B [Source:HGNC Symbol;Acc:HGNC:25206]",{"v":5.47155011454653,"d":"5.47"},{"v":8.5228954131331,"d":"8.52"},{"v":0.641982548103935,"d":"0.64"},{"v":-0.639394015773622,"d":"-0.64"},{"v":0.169315663171949,"d":"0.17"},{"v":0.730729287449554,"d":"0.73"},"down","no"]
["ENSG00000173369","C1QB","ENST00000432749;ENST00000314933;ENST00000510260;ENST00000509305","GO:0005576(extracellular region);GO:0005581(collagen trimer);GO:0005515(protein binding);GO:0006508(proteolysis);GO:0002376(immune system process);GO:0045087(innate immune response);GO:0042803(protein homodimerization activity);GO:0048839(inner ear development);GO:0005615(extracellular space);GO:0004252(serine-type endopeptidase activity);GO:0006956(complement activation);GO:0006958(complement activation, classical pathway);GO:0030449(regulation of complement activation);GO:0070062(extracellular exosome);GO:0072562(blood microparticle);GO:0005602(complement component C1 complex);GO:0005602(complement component C1 complex)","04610(Complement and coagulation cascades);05322(Systemic lupus erythematosus);05020(Prion diseases);05133(Pertussis);05150(Staphylococcus aureus infection);05142(Chagas disease (American trypanosomiasis));05142(Chagas disease (American trypanosomiasis))","K03987","NA","complement C1q B chain [Source:HGNC Symbol;Acc:HGNC:1242]",{"v":0.596345535290443,"d":"0.60"},{"v":0.963410449718926,"d":"0.96"},{"v":0.618994256772309,"d":"0.62"},{"v":-0.692002071174069,"d":"-0.69"},{"v":0.169475922670181,"d":"0.17"},{"v":0.730729287449554,"d":"0.73"},"down","no"]
["ENSG00000157259","GATAD1","ENST00000287957;ENST00000465247;ENST00000493878","GO:0005634(nucleus);GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0005654(nucleoplasm);GO:0006355(regulation of transcription, DNA-templated);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0043565(sequence-specific DNA binding);GO:0031497(chromatin assembly);GO:0031497(chromatin assembly)","NA","NA","NA","GATA zinc finger domain containing 1 [Source:HGNC Symbol;Acc:HGNC:29941]",{"v":1.80158330786892,"d":"1.80"},{"v":0.789633184721353,"d":"0.79"},{"v":2.28154457376898,"d":"2.28"},{"v":1.19001083950668,"d":"1.19"},{"v":0.170963222646598,"d":"0.17"},{"v":0.731937706637505,"d":"0.73"},"up","no"]
["ENSG00000129696","TTI2","ENST00000431156;ENST00000360742;ENST00000520636;ENST00000613904","GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0005813(centrosome);GO:0005813(centrosome)","NA","NA","NA","TELO2 interacting protein 2 [Source:HGNC Symbol;Acc:HGNC:26262]",{"v":1.44941831620085,"d":"1.45"},{"v":2.26335662269067,"d":"2.26"},{"v":0.640384419171994,"d":"0.64"},{"v":-0.642989887996262,"d":"-0.64"},{"v":0.171477299241056,"d":"0.17"},{"v":0.732389068071489,"d":"0.73"},"down","no"]
["MSTRG.2214","TPP1","ENST00000299427;ENST00000533371;ENST00000534644;ENST00000528917;ENST00000428886;ENST00000532191;ENST00000531754;ENST00000524903;ENST00000524924;ENST00000528657;ENST00000524611;ENST00000524788;ENST00000528807;ENST00000530040","GO:0046872(metal ion binding);GO:0016787(hydrolase activity);GO:0005515(protein binding);GO:0008233(peptidase activity);GO:0006508(proteolysis);GO:0004252(serine-type endopeptidase activity);GO:0042470(melanosome);GO:0008236(serine-type peptidase activity);GO:0007399(nervous system development);GO:0005764(lysosome);GO:0045453(bone resorption);GO:0070062(extracellular exosome);GO:0030855(epithelial cell differentiation);GO:0043202(lysosomal lumen);GO:0006629(lipid metabolic process);GO:0007417(central nervous system development);GO:0036498(IRE1-mediated unfolded protein response);GO:0004175(endopeptidase activity);GO:0008240(tripeptidyl-peptidase activity);GO:0042277(peptide binding);GO:0007040(lysosome organization);GO:0030163(protein catabolic process);GO:0043171(peptide catabolic process);GO:0050885(neuromuscular process controlling balance);GO:0005739(mitochondrion);GO:0005739(mitochondrion)","04142(Lysosome);04142(Lysosome)","K01279","EC:3.4.14.9","tripeptidyl peptidase 1 [Source:HGNC Symbol;Acc:HGNC:2073]",{"v":35.4133855419302,"d":"35.41"},{"v":15.7575475182616,"d":"15.76"},{"v":2.24739195619681,"d":"2.25"},{"v":1.1682517595636,"d":"1.17"},{"v":0.173068225274402,"d":"0.17"},{"v":0.733611682383253,"d":"0.73"},"up","no"]
["MSTRG.8187","RABAC1","ENST00000222008;ENST00000601476;ENST00000601891;ENST00000596171;ENST00000601028;ENST00000600292;ENST00000599219;ENST00000595226;ENST00000601078;ENST00000598057","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005737(cytoplasm);GO:0005794(Golgi apparatus);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0030054(cell junction);GO:0045202(synapse);GO:0031410(cytoplasmic vesicle);GO:0042802(identical protein binding);GO:0008021(synaptic vesicle);GO:0008022(protein C-terminus binding);GO:0070064(proline-rich region binding);GO:0070064(proline-rich region binding)","NA","NA","NA","Rab acceptor 1 [Source:HGNC Symbol;Acc:HGNC:9794]",{"v":13.0366628254127,"d":"13.04"},{"v":20.1910994472236,"d":"20.19"},{"v":0.645663841114176,"d":"0.65"},{"v":-0.631144860284614,"d":"-0.63"},{"v":0.173587464791645,"d":"0.17"},{"v":0.733611682383253,"d":"0.73"},"down","no"]
["MSTRG.8015","NR2C2AP","ENST00000331552;ENST00000539693;ENST00000544883;ENST00000420605;ENST00000538165;ENST00000539678;ENST00000537399","GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005515(protein binding);GO:0070062(extracellular exosome);GO:0006367(transcription initiation from RNA polymerase II promoter);GO:0006367(transcription initiation from RNA polymerase II promoter)","NA","NA","NA","nuclear receptor 2C2 associated protein [Source:HGNC Symbol;Acc:HGNC:30763]",{"v":2.34477052508361,"d":"2.34"},{"v":3.66839015830546,"d":"3.67"},{"v":0.639182427140392,"d":"0.64"},{"v":-0.645700349678277,"d":"-0.65"},{"v":0.174744097618638,"d":"0.17"},{"v":0.733879160903766,"d":"0.73"},"down","no"]
["ENSG00000283528","AC073264.3","ENST00000636941","NA","NA","NA","NA",null,{"v":0.772447,"d":"0.77"},{"v":0.331044,"d":"0.33"},{"v":2.33336656154469,"d":"2.33"},{"v":1.22241296612262,"d":"1.22"},{"v":0.175833766024908,"d":"0.18"},{"v":0.733879160903766,"d":"0.73"},"up","no"]
["ENSG00000128908","INO80","ENST00000361937;ENST00000561172;ENST00000561244;ENST00000560799;ENST00000559995","GO:0005634(nucleus);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0005654(nucleoplasm);GO:0016787(hydrolase activity);GO:0003677(DNA binding);GO:0004386(helicase activity);GO:0032508(DNA duplex unwinding);GO:0003779(actin binding);GO:0051301(cell division);GO:0005886(plasma membrane);GO:0006351(transcription, DNA-templated);GO:0045111(intermediate filament cytoskeleton);GO:0006281(DNA repair);GO:0005515(protein binding);GO:0006310(DNA recombination);GO:0006974(cellular response to DNA damage stimulus);GO:0007049(cell cycle);GO:0016604(nuclear body);GO:0031011(Ino80 complex);GO:0005874(microtubule);GO:0016887(ATPase activity);GO:0006338(chromatin remodeling);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0016579(protein deubiquitination);GO:0043014(alpha-tubulin binding);GO:0010571(positive regulation of nuclear cell cycle DNA replication);GO:0000724(double-strand break repair via homologous recombination);GO:0030307(positive regulation of cell growth);GO:0051225(spindle assembly);GO:0071479(cellular response to ionizing radiation);GO:0000070(mitotic sister chromatid segregation);GO:0006302(double-strand break repair);GO:0003678(DNA helicase activity);GO:0034644(cellular response to UV);GO:0070914(UV-damage excision repair);GO:2000045(regulation of G1/S transition of mitotic cell cycle);GO:2000045(regulation of G1/S transition of mitotic cell cycle)","NA","NA","NA","INO80 complex subunit [Source:HGNC Symbol;Acc:HGNC:26956]",{"v":4.35516736926148,"d":"4.36"},{"v":1.94771212403764,"d":"1.95"},{"v":2.23604264486127,"d":"2.24"},{"v":1.16094770291419,"d":"1.16"},{"v":0.176807868780441,"d":"0.18"},{"v":0.733879160903766,"d":"0.73"},"up","no"]
["MSTRG.8496","ID2","ENST00000396290;ENST00000331129;ENST00000472142","GO:0005737(cytoplasm);GO:0005634(nucleus);GO:0046983(protein dimerization activity);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0005515(protein binding);GO:0045892(negative regulation of transcription, DNA-templated);GO:0048511(rhythmic process);GO:0007275(multicellular organism development);GO:0045893(positive regulation of transcription, DNA-templated);GO:0010628(positive regulation of gene expression);GO:0043234(protein complex);GO:0005829(cytosol);GO:0044325(ion channel binding);GO:0010629(negative regulation of gene expression);GO:0032922(circadian regulation of gene expression);GO:0045665(negative regulation of neuron differentiation);GO:0019216(regulation of lipid metabolic process);GO:0048661(positive regulation of smooth muscle cell proliferation);GO:0042752(regulation of circadian rhythm);GO:0090398(cellular senescence);GO:0043153(entrainment of circadian clock by photoperiod);GO:0071158(positive regulation of cell cycle arrest);GO:0048557(embryonic digestive tract morphogenesis);GO:0045475(locomotor rhythm);GO:0048663(neuron fate commitment);GO:0033598(mammary gland epithelial cell proliferation);GO:2000045(regulation of G1/S transition of mitotic cell cycle);GO:0043433(negative regulation of sequence-specific DNA binding transcription factor activity);GO:0045777(positive regulation of blood pressure);GO:0060749(mammary gland alveolus development);GO:0061030(epithelial cell differentiation involved in mammary gland alveolus development);GO:0061031(endodermal digestive tract morphogenesis);GO:0071931(positive regulation of transcription involved in G1/S transition of mitotic cell cycle);GO:2000178(negative regulation of neural precursor cell proliferation);GO:2000178(negative regulation of neural precursor cell proliferation)","04350(TGF-beta signaling pathway);04390(Hippo signaling pathway);04550(Signaling pathways regulating pluripotency of stem cells);05202(Transcriptional misregulation in cancers);05202(Transcriptional misregulation in cancers)","K17693","NA","inhibitor of DNA binding 2, HLH protein [Source:HGNC Symbol;Acc:HGNC:5361]",{"v":26.4533636358277,"d":"26.45"},{"v":40.6393790208617,"d":"40.64"},{"v":0.650929327001975,"d":"0.65"},{"v":-0.619427179942805,"d":"-0.62"},{"v":0.177549443340125,"d":"0.18"},{"v":0.733879160903766,"d":"0.73"},"down","no"]
["MSTRG.9828","ADNP","ENST00000396029;ENST00000396032;ENST00000349014;ENST00000621696;ENST00000371602;ENST00000534467","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0003682(chromatin binding);GO:0005507(copper ion binding);GO:0042277(peptide binding);GO:0048487(beta-tubulin binding);GO:0007614(short-term memory);GO:0009743(response to carbohydrate);GO:0010035(response to inorganic substance);GO:0010629(negative regulation of gene expression);GO:0010835(regulation of protein ADP-ribosylation);GO:0010976(positive regulation of neuron projection development);GO:0030828(positive regulation of cGMP biosynthetic process);GO:0031668(cellular response to extracellular stimulus);GO:0032091(negative regulation of protein binding);GO:0032147(activation of protein kinase activity);GO:0033484(nitric oxide homeostasis);GO:0043524(negative regulation of neuron apoptotic process);GO:0044849(estrous cycle);GO:0045773(positive regulation of axon extension);GO:0050731(positive regulation of peptidyl-tyrosine phosphorylation);GO:0050805(negative regulation of synaptic transmission);GO:0051965(positive regulation of synapse assembly);GO:0005615(extracellular space);GO:0005737(cytoplasm);GO:0030424(axon);GO:0030425(dendrite);GO:0043025(neuronal cell body);GO:0043025(neuronal cell body)","NA","NA","NA","activity dependent neuroprotector homeobox [Source:HGNC Symbol;Acc:HGNC:15766]",{"v":8.47857362999576,"d":"8.48"},{"v":3.8003641652309,"d":"3.80"},{"v":2.23098978449625,"d":"2.23"},{"v":1.15768390762493,"d":"1.16"},{"v":0.177788849243817,"d":"0.18"},{"v":0.733879160903766,"d":"0.73"},"up","no"]
["ENSG00000204613","TRIM10","ENST00000376704;ENST00000449742","GO:0005737(cytoplasm);GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0005622(intracellular);GO:0005515(protein binding);GO:0003674(molecular_function);GO:0008150(biological_process);GO:0030218(erythrocyte differentiation);GO:0045087(innate immune response);GO:0046597(negative regulation of viral entry into host cell);GO:0046597(negative regulation of viral entry into host cell)","NA","NA","NA","tripartite motif containing 10 [Source:HGNC Symbol;Acc:HGNC:10072]",{"v":0.812833537225042,"d":"0.81"},{"v":1.26869273886069,"d":"1.27"},{"v":0.640685890545083,"d":"0.64"},{"v":-0.642310875674056,"d":"-0.64"},{"v":0.179198075025032,"d":"0.18"},{"v":0.735345316348302,"d":"0.74"},"down","no"]
["ENSG00000146063","TRIM41","ENST00000508930;ENST00000351937;ENST00000514219;ENST00000515499;ENST00000315073;ENST00000515223;ENST00000503114;ENST00000515834","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0005730(nucleolus);GO:0016740(transferase activity);GO:0016567(protein ubiquitination);GO:0005622(intracellular);GO:0005515(protein binding);GO:0016604(nuclear body);GO:0042802(identical protein binding);GO:0042802(identical protein binding)","NA","NA","NA","tripartite motif containing 41 [Source:HGNC Symbol;Acc:HGNC:19013]",{"v":1.04593107482621,"d":"1.05"},{"v":0.46604564562993,"d":"0.47"},{"v":2.24426745455905,"d":"2.24"},{"v":1.16624461550706,"d":"1.17"},{"v":0.18054417761971,"d":"0.18"},{"v":0.737594808859475,"d":"0.74"},"up","no"]
["MSTRG.6231","APRT","ENST00000426324;ENST00000378364;ENST00000563655;ENST00000562464;ENST00000567057;ENST00000568575;ENST00000567391;ENST00000569616;ENST00000568319;ENST00000564858","GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0016740(transferase activity);GO:0009116(nucleoside metabolic process);GO:0016757(transferase activity, transferring glycosyl groups);GO:0005576(extracellular region);GO:0070062(extracellular exosome);GO:0006166(purine ribonucleoside salvage);GO:0043312(neutrophil degranulation);GO:0034774(secretory granule lumen);GO:0043101(purine-containing compound salvage);GO:0002055(adenine binding);GO:0003999(adenine phosphoribosyltransferase activity);GO:0016208(AMP binding);GO:0006168(adenine salvage);GO:0007595(lactation);GO:0007625(grooming behavior);GO:0032869(cellular response to insulin stimulus);GO:0044209(AMP salvage);GO:0046083(adenine metabolic process);GO:0046083(adenine metabolic process)","00230(Purine metabolism);00230(Purine metabolism)","K00759","EC:2.4.2.7","adenine phosphoribosyltransferase [Source:HGNC Symbol;Acc:HGNC:626]",{"v":14.4027820011093,"d":"14.40"},{"v":22.0485337842485,"d":"22.05"},{"v":0.653230828954198,"d":"0.65"},{"v":-0.614335214995424,"d":"-0.61"},{"v":0.181270609186682,"d":"0.18"},{"v":0.737594808859475,"d":"0.74"},"down","no"]
["MSTRG.9704","PHF20","ENST00000374012;ENST00000617560;ENST00000496305;ENST00000480940;ENST00000449988;ENST00000461122;ENST00000473943;ENST00000485604;ENST00000339089;ENST00000374000;ENST00000461405;ENST00000481202;ENST00000486408;ENST00000452270","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0006366(transcription from RNA polymerase II promoter);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0016569(covalent chromatin modification);GO:0031965(nuclear membrane);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0001228(transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:1901796(regulation of signal transduction by p53 class mediator);GO:0071339(MLL1 complex);GO:0000977(RNA polymerase II regulatory region sequence-specific DNA binding);GO:0043995(histone acetyltransferase activity (H4-K5 specific));GO:0043996(histone acetyltransferase activity (H4-K8 specific));GO:0046972(histone acetyltransferase activity (H4-K16 specific));GO:0043981(histone H4-K5 acetylation);GO:0043982(histone H4-K8 acetylation);GO:0043984(histone H4-K16 acetylation);GO:0000123(histone acetyltransferase complex);GO:0000123(histone acetyltransferase complex)","NA","NA","NA","PHD finger protein 20 [Source:HGNC Symbol;Acc:HGNC:16098]",{"v":7.61557537969701,"d":"7.62"},{"v":3.43500309101754,"d":"3.44"},{"v":2.21705051725036,"d":"2.22"},{"v":1.14864164352783,"d":"1.15"},{"v":0.183567578146051,"d":"0.18"},{"v":0.741447874870894,"d":"0.74"},"up","no"]
["ENSG00000120875","DUSP4","ENST00000240100","GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0016787(hydrolase activity);GO:0004725(protein tyrosine phosphatase activity);GO:0008138(protein tyrosine/serine/threonine phosphatase activity);GO:0016791(phosphatase activity);GO:0006470(protein dephosphorylation);GO:0016311(dephosphorylation);GO:0004721(phosphoprotein phosphatase activity);GO:0017017(MAP kinase tyrosine/serine/threonine phosphatase activity);GO:0035335(peptidyl-tyrosine dephosphorylation);GO:0070373(negative regulation of ERK1 and ERK2 cascade);GO:0035970(peptidyl-threonine dephosphorylation);GO:0000188(inactivation of MAPK activity);GO:0001706(endoderm formation);GO:0008330(protein tyrosine/threonine phosphatase activity);GO:1990439(MAP kinase threonine phosphatase activity)","04010(MAPK signaling pathway)","K04459","EC:3.1.3.16;EC:3.1.3.48","dual specificity phosphatase 4 [Source:HGNC Symbol;Acc:HGNC:3070]",{"v":0.121939892930963,"d":"0.12"},{"v":0.195951965550503,"d":"0.20"},{"v":0.622294818979681,"d":"0.62"},{"v":-0.684329860012608,"d":"-0.68"},{"v":0.183822237122126,"d":"0.18"},{"v":0.741447874870894,"d":"0.74"},"down","no"]
["ENSG00000120800","UTP20","ENST00000261637;ENST00000551825;ENST00000551998","GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005730(nucleolus);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0005654(nucleoplasm);GO:0006364(rRNA processing);GO:0000462(maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA));GO:0032040(small-subunit processome);GO:0008285(negative regulation of cell proliferation);GO:0030688(preribosome, small subunit precursor);GO:0030686(90S preribosome);GO:0000447(endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA));GO:0000472(endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA));GO:0000480(endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA));GO:0000480(endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA))","NA","NA","NA","UTP20, small subunit processome component [Source:HGNC Symbol;Acc:HGNC:17897]",{"v":1.44947125498803,"d":"1.45"},{"v":0.651210634876297,"d":"0.65"},{"v":2.22581017164035,"d":"2.23"},{"v":1.15433055758956,"d":"1.15"},{"v":0.184483179446505,"d":"0.18"},{"v":0.741447874870894,"d":"0.74"},"up","no"]
["MSTRG.8175","CCDC97","ENST00000269967;ENST00000600918;ENST00000596882","GO:0005686(U2 snRNP);GO:0005686(U2 snRNP)","NA","NA","NA","coiled-coil domain containing 97 [Source:HGNC Symbol;Acc:HGNC:28289]",{"v":3.3468248306726,"d":"3.35"},{"v":5.09914846637006,"d":"5.10"},{"v":0.656349751874377,"d":"0.66"},{"v":-0.607463300119359,"d":"-0.61"},{"v":0.185685036966417,"d":"0.19"},{"v":0.742073324715391,"d":"0.74"},"down","no"]
["ENSG00000140263","SORD","ENST00000267814;ENST00000560488;ENST00000558580;ENST00000558574;ENST00000559230;ENST00000558789","GO:0016020(membrane);GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0030246(carbohydrate binding);GO:0031514(motile cilium);GO:0005739(mitochondrion);GO:0042995(cell projection);GO:0051287(NAD binding);GO:0005615(extracellular space);GO:0042802(identical protein binding);GO:0031966(mitochondrial membrane);GO:0005929(cilium);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0006006(glucose metabolic process);GO:0030317(flagellated sperm motility);GO:0019640(glucuronate catabolic process to xylulose 5-phosphate);GO:0046370(fructose biosynthetic process);GO:0003939(L-iditol 2-dehydrogenase activity);GO:0046526(D-xylulose reductase activity);GO:0006060(sorbitol metabolic process);GO:0006062(sorbitol catabolic process);GO:0006970(response to osmotic stress);GO:0009725(response to hormone);GO:0031667(response to nutrient levels);GO:0042493(response to drug);GO:0046686(response to cadmium ion);GO:0046688(response to copper ion);GO:0051160(L-xylitol catabolic process);GO:0051164(L-xylitol metabolic process);GO:0051164(L-xylitol metabolic process)","00040(Pentose and glucuronate interconversions);00051(Fructose and mannose metabolism);00051(Fructose and mannose metabolism)","K00008","EC:1.1.1.14","sorbitol dehydrogenase [Source:HGNC Symbol;Acc:HGNC:11184]",{"v":0.957451806786816,"d":"0.96"},{"v":1.46157442701737,"d":"1.46"},{"v":0.655082484400527,"d":"0.66"},{"v":-0.610251520537468,"d":"-0.61"},{"v":0.186654917968954,"d":"0.19"},{"v":0.742073324715391,"d":"0.74"},"down","no"]
["ENSG00000188389","PDCD1","ENST00000334409;ENST00000343705","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005515(protein binding);GO:0006915(apoptotic process);GO:0002376(immune system process);GO:0007165(signal transduction);GO:0005886(plasma membrane);GO:0002644(negative regulation of tolerance induction);GO:0043065(positive regulation of apoptotic process);GO:0043066(negative regulation of apoptotic process);GO:0009897(external side of plasma membrane);GO:0070234(positive regulation of T cell apoptotic process);GO:0004871(signal transducer activity);GO:0007275(multicellular organism development);GO:0031295(T cell costimulation);GO:0006959(humoral immune response);GO:0006959(humoral immune response)","04514(Cell adhesion molecules (CAMs));04660(T cell receptor signaling pathway);04660(T cell receptor signaling pathway)","K06744","NA","programmed cell death 1 [Source:HGNC Symbol;Acc:HGNC:8760]",{"v":1.00367318732261,"d":"1.00"},{"v":1.566106,"d":"1.57"},{"v":0.640871810287816,"d":"0.64"},{"v":-0.641892282749913,"d":"-0.64"},{"v":0.187407195255105,"d":"0.19"},{"v":0.743292267246425,"d":"0.74"},"down","no"]
["MSTRG.8572","CAD","ENST00000264705;ENST00000487239;ENST00000464159;ENST00000458503;ENST00000428460;ENST00000456311;ENST00000491891;ENST00000475695","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0005654(nucleoplasm);GO:0016740(transferase activity);GO:0016787(hydrolase activity);GO:0008270(zinc ion binding);GO:0016874(ligase activity);GO:0003824(catalytic activity);GO:0008152(metabolic process);GO:0016810(hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds);GO:0006807(nitrogen compound metabolic process);GO:0004088(carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity);GO:0006207('de novo' pyrimidine nucleobase biosynthetic process);GO:0006541(glutamine metabolic process);GO:0006520(cellular amino acid metabolic process);GO:0006221(pyrimidine nucleotide biosynthetic process);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0004070(aspartate carbamoyltransferase activity);GO:0016597(amino acid binding);GO:0016743(carboxyl- or carbamoyltransferase activity);GO:0016812(hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides);GO:0044205('de novo' UMP biosynthetic process);GO:0019899(enzyme binding);GO:0042802(identical protein binding);GO:0016363(nuclear matrix);GO:0004672(protein kinase activity);GO:0018107(peptidyl-threonine phosphorylation);GO:0042995(cell projection);GO:0043025(neuronal cell body);GO:0043195(terminal bouton);GO:0046777(protein autophosphorylation);GO:0017144(drug metabolic process);GO:0046134(pyrimidine nucleoside biosynthetic process);GO:0004087(carbamoyl-phosphate synthase (ammonia) activity);GO:0004151(dihydroorotase activity);GO:0070335(aspartate binding);GO:0000050(urea cycle);GO:0006526(arginine biosynthetic process);GO:0006526(arginine biosynthetic process)","00240(Pyrimidine metabolism);00250(Alanine, aspartate and glutamate metabolism);00250(Alanine, aspartate and glutamate metabolism)","K11540","EC:6.3.5.5;EC:2.1.3.2","carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase [Source:HGNC Symbol;Acc:HGNC:1424]",{"v":2.90121783887438,"d":"2.90"},{"v":1.31828857955355,"d":"1.32"},{"v":2.20074563632866,"d":"2.20"},{"v":1.13799240719508,"d":"1.14"},{"v":0.189388726072534,"d":"0.19"},{"v":0.744792169278814,"d":"0.74"},"up","no"]
["MSTRG.13628","AEBP1","ENST00000223357;ENST00000453052;ENST00000434445;ENST00000431035;ENST00000454218;ENST00000450684","GO:0005615(extracellular space);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0008270(zinc ion binding);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0006508(proteolysis);GO:0005576(extracellular region);GO:0004181(metallocarboxypeptidase activity);GO:0005516(calmodulin binding);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0070062(extracellular exosome);GO:0031012(extracellular matrix);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0001501(skeletal system development);GO:0000977(RNA polymerase II regulatory region sequence-specific DNA binding);GO:0007517(muscle organ development);GO:0001227(transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding);GO:0016485(protein processing);GO:0006518(peptide metabolic process);GO:0004180(carboxypeptidase activity);GO:0004185(serine-type carboxypeptidase activity);GO:0003714(transcription corepressor activity);GO:0003714(transcription corepressor activity)","NA","NA","NA","AE binding protein 1 [Source:HGNC Symbol;Acc:HGNC:303]",{"v":1.04657964883956,"d":"1.05"},{"v":0.471317202018164,"d":"0.47"},{"v":2.2205420136548,"d":"2.22"},{"v":1.15091186800307,"d":"1.15"},{"v":0.190517117128393,"d":"0.19"},{"v":0.745987695641138,"d":"0.75"},"up","no"]
["ENSG00000177853","ZNF518A","ENST00000534948;ENST00000316045;ENST00000614149;ENST00000624776;ENST00000563195;ENST00000442635;ENST00000539666;ENST00000484770;ENST00000488700","GO:0005634(nucleus);GO:0003676(nucleic acid binding);GO:0046872(metal ion binding);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0000981(RNA polymerase II transcription factor activity, sequence-specific DNA binding);GO:0000981(RNA polymerase II transcription factor activity, sequence-specific DNA binding)","NA","NA","NA","zinc finger protein 518A [Source:HGNC Symbol;Acc:HGNC:29009]",{"v":1.89600755476999,"d":"1.90"},{"v":2.86381355596364,"d":"2.86"},{"v":0.662056910381516,"d":"0.66"},{"v":-0.594972858525194,"d":"-0.59"},{"v":0.190997365900621,"d":"0.19"},{"v":0.746207802397715,"d":"0.75"},"down","no"]
["MSTRG.10075","TRAPPC10","ENST00000291574;ENST00000380221;ENST00000422875;ENST00000485621;ENST00000469521;MSTRG.10075.10;ENST00000486746;ENST00000468864;ENST00000461889;ENST00000465905;ENST00000459741;ENST00000481460","GO:0006810(transport);GO:0005794(Golgi apparatus);GO:0043547(positive regulation of GTPase activity);GO:0005515(protein binding);GO:0035725(sodium ion transmembrane transport);GO:0016192(vesicle-mediated transport);GO:0006891(intra-Golgi vesicle-mediated transport);GO:0034498(early endosome to Golgi transport);GO:1990071(TRAPPII protein complex);GO:0000139(Golgi membrane);GO:0005829(cytosol);GO:0017112(Rab guanyl-nucleotide exchange factor activity);GO:0061024(membrane organization);GO:0006814(sodium ion transport);GO:0016021(integral component of membrane);GO:0051259(protein oligomerization);GO:0048208(COPII vesicle coating);GO:0030008(TRAPP complex);GO:0015081(sodium ion transmembrane transporter activity);GO:0015081(sodium ion transmembrane transporter activity)","NA","NA","NA","trafficking protein particle complex 10 [Source:HGNC Symbol;Acc:HGNC:11868]",{"v":6.29257102813835,"d":"6.29"},{"v":2.87247847525333,"d":"2.87"},{"v":2.19064166445439,"d":"2.19"},{"v":1.13135351390637,"d":"1.13"},{"v":0.19207327947766,"d":"0.19"},{"v":0.747001672663787,"d":"0.75"},"up","no"]
["MSTRG.8467","ZNF8;AC020915.1;ZNF544;AC020915.2;AC020915.6","ENST00000621650;ENST00000590505;ENST00000413518;ENST00000600220;ENST00000434052;ENST00000596825;ENST00000596652;ENST00000600044;ENST00000591325;ENST00000599227;ENST00000597240;ENST00000596597;ENST00000627781;ENST00000595981;ENST00000594384;ENST00000596677;ENST00000637310;ENST00000609864;ENST00000608004;ENST00000269829;ENST00000602260;ENST00000608070;ENST00000597564;ENST00000427361","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0005622(intracellular);GO:0008270(zinc ion binding);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0030509(BMP signaling pathway);GO:0005515(protein binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding)","NA","NA","NA","zinc finger protein 8 [Source:HGNC Symbol;Acc:HGNC:13154];zinc finger protein 544 [Source:HGNC Symbol;Acc:HGNC:16759]",{"v":0.769498635000635,"d":"0.77"},{"v":1.16305812841472,"d":"1.16"},{"v":0.661616660595875,"d":"0.66"},{"v":-0.595932530486384,"d":"-0.60"},{"v":0.19281425104592,"d":"0.19"},{"v":0.747246799701993,"d":"0.75"},"down","no"]
["MSTRG.10907","UQCRC1","ENST00000203407;ENST00000415995;ENST00000480561;ENST00000460105;ENST00000463708;ENST00000471189;ENST00000467690;ENST00000472438;ENST00000412343","GO:0016020(membrane);GO:0005829(cytosol);GO:0055114(oxidation-reduction process);GO:0005739(mitochondrion);GO:0005743(mitochondrial inner membrane);GO:0046872(metal ion binding);GO:0003824(catalytic activity);GO:1902600(hydrogen ion transmembrane transport);GO:0070469(respiratory chain);GO:0006122(mitochondrial electron transport, ubiquinol to cytochrome c);GO:0005750(mitochondrial respiratory chain complex III);GO:0008270(zinc ion binding);GO:0031625(ubiquitin protein ligase binding);GO:0004222(metalloendopeptidase activity);GO:0016485(protein processing);GO:0009060(aerobic respiration);GO:0008121(ubiquinol-cytochrome-c reductase activity);GO:0006119(oxidative phosphorylation);GO:0005746(mitochondrial respiratory chain);GO:0032403(protein complex binding);GO:0014823(response to activity);GO:0043279(response to alkaloid);GO:0043209(myelin sheath);GO:0043209(myelin sheath)","00190(Oxidative phosphorylation);04260(Cardiac muscle contraction);05010(Alzheimer's disease);05012(Parkinson's disease);05016(Huntington's disease);04932(Non-alcoholic fatty liver disease (NAFLD));04932(Non-alcoholic fatty liver disease (NAFLD))","K00414","NA","ubiquinol-cytochrome c reductase core protein I [Source:HGNC Symbol;Acc:HGNC:12585]",{"v":13.4103194332509,"d":"13.41"},{"v":20.1511725377009,"d":"20.15"},{"v":0.665485812707002,"d":"0.67"},{"v":-0.587520184806432,"d":"-0.59"},{"v":0.193894589753609,"d":"0.19"},{"v":0.747575654318943,"d":"0.75"},"down","no"]
["MSTRG.3461","SMARCC2","ENST00000267064;ENST00000550164;ENST00000550859;ENST00000547356;ENST00000549757;MSTRG.3461.6;ENST00000550150;ENST00000394023;ENST00000552627;ENST00000552566;ENST00000548130;ENST00000552931","GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0016569(covalent chromatin modification);GO:0003677(DNA binding);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0000790(nuclear chromatin);GO:0005515(protein binding);GO:0007399(nervous system development);GO:0045893(positive regulation of transcription, DNA-templated);GO:0006338(chromatin remodeling);GO:0090544(BAF-type complex);GO:0043234(protein complex);GO:0003713(transcription coactivator activity);GO:0045892(negative regulation of transcription, DNA-templated);GO:0006337(nucleosome disassembly);GO:0016514(SWI/SNF complex);GO:0071564(npBAF complex);GO:0071565(nBAF complex);GO:0017053(transcriptional repressor complex);GO:0031492(nucleosomal DNA binding);GO:0043044(ATP-dependent chromatin remodeling);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:0000980(RNA polymerase II distal enhancer sequence-specific DNA binding);GO:0003682(chromatin binding);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0021882(regulation of transcription from RNA polymerase II promoter involved in forebrain neuron fate commitment);GO:0021882(regulation of transcription from RNA polymerase II promoter involved in forebrain neuron fate commitment)","05225(Hepatocellular carcinoma);05225(Hepatocellular carcinoma)","K11649","NA","SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 2 [Source:HGNC Symbol;Acc:HGNC:11105]",{"v":7.35481049456458,"d":"7.35"},{"v":3.37587889105786,"d":"3.38"},{"v":2.17863576624335,"d":"2.18"},{"v":1.12342502061267,"d":"1.12"},{"v":0.195918453494848,"d":"0.20"},{"v":0.749715537309879,"d":"0.75"},"up","no"]
["ENSG00000185404","SP140L","ENST00000243810;ENST00000415673;ENST00000444636;ENST00000483728;ENST00000396563;ENST00000466656;ENST00000462156;ENST00000497212;ENST00000458341;ENST00000496870","GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0003677(DNA binding);GO:0016604(nuclear body);GO:0016604(nuclear body)","NA","NA","NA","SP140 nuclear body protein like [Source:HGNC Symbol;Acc:HGNC:25105]",{"v":3.60187894973451,"d":"3.60"},{"v":1.64745613539823,"d":"1.65"},{"v":2.18632767959181,"d":"2.19"},{"v":1.12850964359621,"d":"1.13"},{"v":0.196886611167147,"d":"0.20"},{"v":0.749715537309879,"d":"0.75"},"up","no"]
["MSTRG.13066","POLR1C","ENST00000372389;ENST00000488601;ENST00000304004;ENST00000481352;ENST00000512472;ENST00000455605","GO:0005634(nucleus);GO:0046983(protein dimerization activity);GO:0003677(DNA binding);GO:0006351(transcription, DNA-templated);GO:0003899(DNA-directed 5'-3' RNA polymerase activity);GO:0005515(protein binding);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0045815(positive regulation of gene expression, epigenetic);GO:0001056(RNA polymerase III activity);GO:0006383(transcription from RNA polymerase III promoter);GO:0032481(positive regulation of type I interferon production);GO:0005666(DNA-directed RNA polymerase III complex);GO:0001054(RNA polymerase I activity);GO:0006360(transcription from RNA polymerase I promoter);GO:0006361(transcription initiation from RNA polymerase I promoter);GO:0006362(transcription elongation from RNA polymerase I promoter);GO:0006363(termination of RNA polymerase I transcription);GO:0005736(DNA-directed RNA polymerase I complex);GO:0005736(DNA-directed RNA polymerase I complex)","00230(Purine metabolism);00240(Pyrimidine metabolism);03020(RNA polymerase);04623(Cytosolic DNA-sensing pathway);05169(Epstein-Barr virus infection);05169(Epstein-Barr virus infection)","K03027","NA","RNA polymerase I subunit C [Source:HGNC Symbol;Acc:HGNC:20194]",{"v":1.82320443355424,"d":"1.82"},{"v":2.7511688437391,"d":"2.75"},{"v":0.662701759546074,"d":"0.66"},{"v":-0.593568344953891,"d":"-0.59"},{"v":0.197611729014092,"d":"0.20"},{"v":0.749843715609006,"d":"0.75"},"down","no"]
["MSTRG.15067","RALGDS","ENST00000393160;ENST00000372062;ENST00000372050;ENST00000372047;ENST00000493438;ENST00000393157;ENST00000477660;ENST00000424572;MSTRG.15067.1;ENST00000471109;ENST00000482648;ENST00000493067;ENST00000495621;ENST00000498797;ENST00000460587;ENST00000469972","GO:0005622(intracellular);GO:0007264(small GTPase mediated signal transduction);GO:0043547(positive regulation of GTPase activity);GO:0005085(guanyl-nucleotide exchange factor activity);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0007165(signal transduction);GO:0005829(cytosol);GO:0050790(regulation of catalytic activity);GO:0005515(protein binding);GO:0005903(brush border);GO:0030695(GTPase regulator activity);GO:0007265(Ras protein signal transduction);GO:0007265(Ras protein signal transduction)","04014(Ras signaling pathway);04015(Rap1 signaling pathway);04072(Phospholipase D signaling pathway);05200(Pathways in cancer);05231(Choline metabolism in cancer);05210(Colorectal cancer);05212(Pancreatic cancer);05212(Pancreatic cancer)","K08732","NA","ral guanine nucleotide dissociation stimulator [Source:HGNC Symbol;Acc:HGNC:9842]",{"v":6.96762863109716,"d":"6.97"},{"v":3.20256843951877,"d":"3.20"},{"v":2.1756376991413,"d":"2.18"},{"v":1.12143832994739,"d":"1.12"},{"v":0.19786160243215,"d":"0.20"},{"v":0.749843715609006,"d":"0.75"},"up","no"]
["MSTRG.9957","PPIAP22","ENST00000358455","NA","NA","NA","NA","peptidylprolyl isomerase A pseudogene 22 [Source:HGNC Symbol;Acc:HGNC:17236]",{"v":56.349293,"d":"56.35"},{"v":84.067368,"d":"84.07"},{"v":0.670287346215002,"d":"0.67"},{"v":-0.577148396198861,"d":"-0.58"},{"v":0.199481945098686,"d":"0.20"},{"v":0.750818450035425,"d":"0.75"},"down","no"]
["MSTRG.4087","RPS26P47","ENST00000427219","NA","NA","NA","NA","ribosomal protein S26 pseudogene 47 [Source:HGNC Symbol;Acc:HGNC:36368]",{"v":10.30836,"d":"10.31"},{"v":15.4851,"d":"15.49"},{"v":0.665695410426797,"d":"0.67"},{"v":-0.587065873119676,"d":"-0.59"},{"v":0.200295837269418,"d":"0.20"},{"v":0.750818450035425,"d":"0.75"},"down","no"]
["ENSG00000073060","SCARB1","ENST00000545493;ENST00000535005;ENST00000538291;ENST00000261693;ENST00000544327;ENST00000339570;ENST00000539320;ENST00000546215","GO:0010595(positive regulation of endothelial cell migration);GO:0042632(cholesterol homeostasis);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0043231(intracellular membrane-bounded organelle);GO:0005765(lysosomal membrane);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0005901(caveola);GO:0006898(receptor-mediated endocytosis);GO:0046718(viral entry into host cell);GO:0070062(extracellular exosome);GO:0016032(viral process);GO:0009986(cell surface);GO:0005215(transporter activity);GO:0001530(lipopolysaccharide binding);GO:0030666(endocytic vesicle membrane);GO:0015914(phospholipid transport);GO:0051000(positive regulation of nitric-oxide synthase activity);GO:0001618(virus receptor activity);GO:0033344(cholesterol efflux);GO:0034384(high-density lipoprotein particle clearance);GO:0031663(lipopolysaccharide-mediated signaling pathway);GO:0034375(high-density lipoprotein particle remodeling);GO:0043691(reverse cholesterol transport);GO:0034185(apolipoprotein binding);GO:0034186(apolipoprotein A-I binding);GO:0030169(low-density lipoprotein particle binding);GO:0010867(positive regulation of triglyceride biosynthetic process);GO:0010899(regulation of phosphatidylcholine catabolic process);GO:0034383(low-density lipoprotein particle clearance);GO:0070508(cholesterol import);GO:0042060(wound healing);GO:0070328(triglyceride homeostasis);GO:0010886(positive regulation of cholesterol storage);GO:0044406(adhesion of symbiont to host);GO:0050764(regulation of phagocytosis);GO:0005044(scavenger receptor activity);GO:0015920(lipopolysaccharide transport);GO:0001786(phosphatidylserine binding);GO:0001875(lipopolysaccharide receptor activity);GO:0005545(1-phosphatidylinositol binding);GO:0070506(high-density lipoprotein particle receptor activity);GO:0032497(detection of lipopolysaccharide);GO:0035461(vitamin transmembrane transport);GO:0043654(recognition of apoptotic cell);GO:0001540(amyloid-beta binding);GO:0008035(high-density lipoprotein particle binding);GO:0042803(protein homodimerization activity);GO:0001935(endothelial cell proliferation);GO:0006702(androgen biosynthetic process);GO:0006707(cholesterol catabolic process);GO:0006869(lipid transport);GO:0006910(phagocytosis, recognition);GO:0030301(cholesterol transport);GO:0043534(blood vessel endothelial cell migration);GO:0050892(intestinal absorption);GO:0005737(cytoplasm);GO:0005887(integral component of plasma membrane);GO:0031528(microvillus membrane);GO:0031528(microvillus membrane)","04145(Phagosome);04913(Ovarian Steroidogenesis);04925(Aldosterone synthesis and secretion);04927(Cortisol synthesis and secretion);04976(Bile secretion);04975(Fat digestion and absorption);04979(Cholesterol metabolism);04977(Vitamin digestion and absorption);05160(Hepatitis C);05160(Hepatitis C)","K13885","NA","scavenger receptor class B member 1 [Source:HGNC Symbol;Acc:HGNC:1664]",{"v":0.617547564009818,"d":"0.62"},{"v":0.281499142875597,"d":"0.28"},{"v":2.19378132985197,"d":"2.19"},{"v":1.13341972899524,"d":"1.13"},{"v":0.201716810547257,"d":"0.20"},{"v":0.753954721881332,"d":"0.75"},"up","no"]
["MSTRG.14217","SORBS3","ENST00000523965;ENST00000522315;ENST00000522721;ENST00000523402;ENST00000519453;ENST00000240123;ENST00000522037;ENST00000517535;ENST00000523348;ENST00000524057;ENST00000520207;ENST00000519127;ENST00000520574","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0007015(actin filament organization);GO:0007155(cell adhesion);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0030054(cell junction);GO:0005925(focal adhesion);GO:0005829(cytosol);GO:0005200(structural constituent of cytoskeleton);GO:0051496(positive regulation of stress fiber assembly);GO:0006936(muscle contraction);GO:0017166(vinculin binding);GO:0008134(transcription factor binding);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0031589(cell-substrate adhesion);GO:0043410(positive regulation of MAPK cascade);GO:0051495(positive regulation of cytoskeleton organization);GO:0051495(positive regulation of cytoskeleton organization)","NA","NA","NA","sorbin and SH3 domain containing 3 [Source:HGNC Symbol;Acc:HGNC:30907]",{"v":1.1323096271937,"d":"1.13"},{"v":0.518070115958668,"d":"0.52"},{"v":2.18563007653589,"d":"2.19"},{"v":1.12804924185677,"d":"1.13"},{"v":0.203486209687111,"d":"0.20"},{"v":0.756671582803848,"d":"0.76"},"up","no"]
["MSTRG.8819","PRADC1","ENST00000258083;ENST00000470391","GO:0005515(protein binding);GO:0005576(extracellular region);GO:0070062(extracellular exosome);GO:0070062(extracellular exosome)","NA","NA","NA","protease associated domain containing 1 [Source:HGNC Symbol;Acc:HGNC:16047]",{"v":2.32104696801706,"d":"2.32"},{"v":3.50250485998579,"d":"3.50"},{"v":0.662682012103326,"d":"0.66"},{"v":-0.593611335577943,"d":"-0.59"},{"v":0.204520023471132,"d":"0.20"},{"v":0.758491777168893,"d":"0.76"},"down","no"]
["MSTRG.8622","HEATR5B","ENST00000233099;ENST00000467978;ENST00000478810;ENST00000425467;ENST00000471051","GO:0016020(membrane);GO:0070062(extracellular exosome);GO:0070062(extracellular exosome)","NA","NA","NA","HEAT repeat containing 5B [Source:HGNC Symbol;Acc:HGNC:29273]",{"v":5.62244360419205,"d":"5.62"},{"v":2.61598116951011,"d":"2.62"},{"v":2.1492676131323,"d":"2.15"},{"v":1.10384512916006,"d":"1.10"},{"v":0.205909298923728,"d":"0.21"},{"v":0.758780956552582,"d":"0.76"},"up","no"]
["MSTRG.457","AL050341.2","ENST00000567508","NA","NA","NA","NA",null,{"v":1.088576,"d":"1.09"},{"v":1.655087,"d":"1.66"},{"v":0.657715274181961,"d":"0.66"},{"v":-0.604464920387114,"d":"-0.60"},{"v":0.206131912012129,"d":"0.21"},{"v":0.758975870068755,"d":"0.76"},"down","no"]
["ENSG00000155254","MARVELD1","ENST00000285605;ENST00000451097","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005886(plasma membrane);GO:0005856(cytoskeleton);GO:0007049(cell cycle);GO:0008104(protein localization);GO:0019911(structural constituent of myelin sheath);GO:0042552(myelination);GO:0045121(membrane raft);GO:0001766(membrane raft polarization);GO:0001766(membrane raft polarization)","NA","NA","NA","MARVEL domain containing 1 [Source:HGNC Symbol;Acc:HGNC:28674]",{"v":1.58991190944066,"d":"1.59"},{"v":0.732762724770642,"d":"0.73"},{"v":2.16974998276326,"d":"2.17"},{"v":1.11752881252774,"d":"1.12"},{"v":0.207640104120451,"d":"0.21"},{"v":0.759711571881158,"d":"0.76"},"up","no"]
["ENSG00000188157","AGRN","ENST00000620552;ENST00000466223;ENST00000478677;ENST00000461111","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005829(cytosol);GO:0005509(calcium ion binding);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0007010(cytoskeleton organization);GO:0007165(signal transduction);GO:0005576(extracellular region);GO:0043236(laminin binding);GO:0007275(multicellular organism development);GO:0005578(proteinaceous extracellular matrix);GO:0030054(cell junction);GO:0045202(synapse);GO:0030154(cell differentiation);GO:0005200(structural constituent of cytoskeleton);GO:0007213(G-protein coupled acetylcholine receptor signaling pathway);GO:0043113(receptor clustering);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0070062(extracellular exosome);GO:0043547(positive regulation of GTPase activity);GO:0031012(extracellular matrix);GO:0043202(lysosomal lumen);GO:0002162(dystroglycan binding);GO:0033691(sialic acid binding);GO:0035374(chondroitin sulfate binding);GO:0043395(heparan sulfate proteoglycan binding);GO:0001523(retinoid metabolic process);GO:0006024(glycosaminoglycan biosynthetic process);GO:0006027(glycosaminoglycan catabolic process);GO:0030198(extracellular matrix organization);GO:0030203(glycosaminoglycan metabolic process);GO:0045162(clustering of voltage-gated sodium channels);GO:0045887(positive regulation of synaptic growth at neuromuscular junction);GO:0050808(synapse organization);GO:0051491(positive regulation of filopodium assembly);GO:0005605(basal lamina);GO:0005796(Golgi lumen);GO:0005796(Golgi lumen)","04512(ECM-receptor interaction);04512(ECM-receptor interaction)","K06254","NA","agrin [Source:HGNC Symbol;Acc:HGNC:329]",{"v":0.244211794943298,"d":"0.24"},{"v":0.110284280256553,"d":"0.11"},{"v":2.21438444695102,"d":"2.21"},{"v":1.14690571514587,"d":"1.15"},{"v":0.209152387733392,"d":"0.21"},{"v":0.760929410635301,"d":"0.76"},"up","no"]
["MSTRG.1741","HNRNPH3","ENST00000265866;ENST00000354695;ENST00000481819;MSTRG.1741.3;ENST00000469172;ENST00000491200;ENST00000467249;ENST00000461310;ENST00000486854;ENST00000478698;ENST00000480987;ENST00000490442","GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0006397(mRNA processing);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0030529(intracellular ribonucleoprotein complex);GO:0005515(protein binding);GO:0005681(spliceosomal complex);GO:0000398(mRNA splicing, via spliceosome);GO:0030855(epithelial cell differentiation);GO:0008380(RNA splicing);GO:0006396(RNA processing);GO:0019013(viral nucleocapsid);GO:0019013(viral nucleocapsid)","NA","NA","NA","heterogeneous nuclear ribonucleoprotein H3 [Source:HGNC Symbol;Acc:HGNC:5043]",{"v":11.468420340197,"d":"11.47"},{"v":5.35615090134288,"d":"5.36"},{"v":2.14116826643582,"d":"2.14"},{"v":1.09839817620617,"d":"1.10"},{"v":0.209646992509655,"d":"0.21"},{"v":0.761197270338271,"d":"0.76"},"up","no"]
["MSTRG.8483","TMEM18","ENST00000281017;ENST00000432667;ENST00000497508;ENST00000418447;ENST00000461640;ENST00000477202;ENST00000355654","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0031965(nuclear membrane);GO:0016477(cell migration);GO:0016477(cell migration)","NA","NA","NA","transmembrane protein 18 [Source:HGNC Symbol;Acc:HGNC:25257]",{"v":1.8205475519429,"d":"1.82"},{"v":2.68463168100714,"d":"2.68"},{"v":0.678136805440634,"d":"0.68"},{"v":-0.560351746863296,"d":"-0.56"},{"v":0.211528957652992,"d":"0.21"},{"v":0.762916686011368,"d":"0.76"},"down","no"]
["ENSG00000151893","CACUL1","ENST00000369151;ENST00000493518;ENST00000477583;ENST00000490610;ENST00000544392;ENST00000481360;ENST00000489169","GO:0005515(protein binding);GO:0007049(cell cycle);GO:0006511(ubiquitin-dependent protein catabolic process);GO:0031625(ubiquitin protein ligase binding);GO:0061630(ubiquitin protein ligase activity);GO:0019901(protein kinase binding);GO:0042787(protein ubiquitination involved in ubiquitin-dependent protein catabolic process);GO:0008284(positive regulation of cell proliferation);GO:0045860(positive regulation of protein kinase activity);GO:0000082(G1/S transition of mitotic cell cycle);GO:0031461(cullin-RING ubiquitin ligase complex);GO:0031461(cullin-RING ubiquitin ligase complex)","NA","NA","NA","CDK2 associated cullin domain 1 [Source:HGNC Symbol;Acc:HGNC:23727]",{"v":5.10346997871997,"d":"5.10"},{"v":2.39093404384975,"d":"2.39"},{"v":2.13450889281021,"d":"2.13"},{"v":1.09390417316717,"d":"1.09"},{"v":0.211613646610125,"d":"0.21"},{"v":0.76295227509574,"d":"0.76"},"up","no"]
["MSTRG.8075","TMEM147","ENST00000222284;ENST00000595180;ENST00000596232;ENST00000392204;ENST00000477168;ENST00000599895;ENST00000595467;ENST00000392205","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005515(protein binding);GO:0031648(protein destabilization);GO:0031648(protein destabilization)","NA","NA","NA","transmembrane protein 147 [Source:HGNC Symbol;Acc:HGNC:30414]",{"v":3.78612046014493,"d":"3.79"},{"v":5.55964032142857,"d":"5.56"},{"v":0.681000971511062,"d":"0.68"},{"v":-0.554271238510233,"d":"-0.55"},{"v":0.213196216127725,"d":"0.21"},{"v":0.762968213948187,"d":"0.76"},"down","no"]
["MSTRG.15142","SLC25A6","ENST00000381401;ENST00000475167;ENST00000484026","GO:0006810(transport);GO:0005634(nucleus);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005215(transporter activity);GO:0055085(transmembrane transport);GO:0005739(mitochondrion);GO:0005743(mitochondrial inner membrane);GO:0005515(protein binding);GO:0006915(apoptotic process);GO:0016032(viral process);GO:0031012(extracellular matrix);GO:0050796(regulation of insulin secretion);GO:0015866(ADP transport);GO:0046732(active induction of host immune response by virus);GO:0005471(ATP:ADP antiporter activity);GO:0015207(adenine transmembrane transporter activity);GO:0015853(adenine transport);GO:0015867(ATP transport);GO:0046902(regulation of mitochondrial membrane permeability);GO:0006626(protein targeting to mitochondrion);GO:0005744(mitochondrial inner membrane presequence translocase complex);GO:0005744(mitochondrial inner membrane presequence translocase complex)","04020(Calcium signaling pathway);04022(cGMP - PKG signaling pathway);04217(Necroptosis);04218(Cellular senescence);05012(Parkinson's disease);05016(Huntington's disease);05166(HTLV-I infection);05164(Influenza A);05164(Influenza A)","K05863","NA","solute carrier family 25 member 6 [Source:HGNC Symbol;Acc:HGNC:10992]",{"v":87.0518594343808,"d":"87.05"},{"v":127.362067486137,"d":"127.36"},{"v":0.683499107329238,"d":"0.68"},{"v":-0.548988641258693,"d":"-0.55"},{"v":0.213531783696026,"d":"0.21"},{"v":0.762968213948187,"d":"0.76"},"down","no"]
["ENSG00000074603","DPP8","ENST00000300141;ENST00000559233;ENST00000341861;ENST00000321147;ENST00000560048;ENST00000560436;ENST00000560194;ENST00000558529;ENST00000559526;ENST00000558786;ENST00000395652;ENST00000560665;ENST00000560597;ENST00000358939","GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0016787(hydrolase activity);GO:0008233(peptidase activity);GO:0006508(proteolysis);GO:0006955(immune response);GO:0008236(serine-type peptidase activity);GO:0004177(aminopeptidase activity);GO:0008239(dipeptidyl-peptidase activity);GO:0008239(dipeptidyl-peptidase activity)","NA","NA","NA","dipeptidyl peptidase 8 [Source:HGNC Symbol;Acc:HGNC:16490]",{"v":2.21557322465968,"d":"2.22"},{"v":1.03706068788561,"d":"1.04"},{"v":2.13639688645113,"d":"2.14"},{"v":1.09517968678474,"d":"1.10"},{"v":0.214775723134512,"d":"0.21"},{"v":0.763821038675482,"d":"0.76"},"up","no"]
["MSTRG.11944","FRG1","ENST00000524583;ENST00000226798;ENST00000507103;ENST00000514482;ENST00000533157;ENST00000531991;ENST00000505327","GO:0003723(RNA binding);GO:0006397(mRNA processing);GO:0008380(RNA splicing);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0003779(actin binding);GO:0005515(protein binding);GO:0005681(spliceosomal complex);GO:0042254(ribosome biogenesis);GO:0005730(nucleolus);GO:0006364(rRNA processing);GO:0051015(actin filament binding);GO:0007517(muscle organ development);GO:0000398(mRNA splicing, via spliceosome);GO:0030018(Z disc);GO:0015030(Cajal body);GO:0071013(catalytic step 2 spliceosome);GO:0055120(striated muscle dense body);GO:0055120(striated muscle dense body)","NA","NA","NA","FSHD region gene 1 [Source:HGNC Symbol;Acc:HGNC:3954]",{"v":8.03689101874634,"d":"8.04"},{"v":11.7513643479789,"d":"11.75"},{"v":0.683911312827995,"d":"0.68"},{"v":-0.548118841178,"d":"-0.55"},{"v":0.216325277590601,"d":"0.22"},{"v":0.764055131571732,"d":"0.76"},"down","no"]
["ENSG00000242265","PEG10","ENST00000612941;ENST00000615790;ENST00000612748;ENST00000488574;ENST00000482108;ENST00000617526","GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0005829(cytosol);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0006915(apoptotic process);GO:0030154(cell differentiation);GO:0030512(negative regulation of transforming growth factor beta receptor signaling pathway);GO:0001890(placenta development);GO:0001890(placenta development)","NA","NA","NA","paternally expressed 10 [Source:HGNC Symbol;Acc:HGNC:14005]",{"v":0.28036569277919,"d":"0.28"},{"v":0.129844981910599,"d":"0.13"},{"v":2.15923394692471,"d":"2.16"},{"v":1.11051956377871,"d":"1.11"},{"v":0.216767577735642,"d":"0.22"},{"v":0.764214292727387,"d":"0.76"},"up","no"]
["ENSG00000157693","TMEM268","ENST00000288502;ENST00000374049;ENST00000471206","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0003674(molecular_function);GO:0008150(biological_process);GO:0005575(cellular_component);GO:0005575(cellular_component)","NA","NA","NA","transmembrane protein 268 [Source:HGNC Symbol;Acc:HGNC:24513]",{"v":0.767403532971619,"d":"0.77"},{"v":0.357973542988314,"d":"0.36"},{"v":2.14374371515124,"d":"2.14"},{"v":1.10013244171883,"d":"1.10"},{"v":0.218168003951027,"d":"0.22"},{"v":0.765664862460948,"d":"0.77"},"up","no"]
["MSTRG.3347","TUBA1B","ENST00000336023;ENST00000547765;ENST00000550367;ENST00000549870;ENST00000551324;ENST00000332858","GO:0005737(cytoplasm);GO:0005525(GTP binding);GO:0000166(nucleotide binding);GO:0003924(GTPase activity);GO:0015630(microtubule cytoskeleton);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0005200(structural constituent of cytoskeleton);GO:0005874(microtubule);GO:0007017(microtubule-based process);GO:0070062(extracellular exosome);GO:0031625(ubiquitin protein ligase binding);GO:0003725(double-stranded RNA binding);GO:0005198(structural molecule activity);GO:0030705(cytoskeleton-dependent intracellular transport);GO:0051301(cell division);GO:0000226(microtubule cytoskeleton organization);GO:0071353(cellular response to interleukin-4);GO:0005881(cytoplasmic microtubule);GO:0043209(myelin sheath);GO:0045121(membrane raft);GO:0007010(cytoskeleton organization);GO:0007010(cytoskeleton organization)","04145(Phagosome);04210(Apoptosis);04530(Tight junction);04540(Gap junction);05130(Pathogenic Escherichia coli infection);05130(Pathogenic Escherichia coli infection)","K07374","NA","tubulin alpha 1b [Source:HGNC Symbol;Acc:HGNC:18809]",{"v":44.0601348265249,"d":"44.06"},{"v":64.0204796343033,"d":"64.02"},{"v":0.688219380395218,"d":"0.69"},{"v":-0.539059575659913,"d":"-0.54"},{"v":0.219107830844858,"d":"0.22"},{"v":0.767172855755794,"d":"0.77"},"down","no"]
["ENSG00000114446","IFT57","ENST00000264538;ENST00000492106;ENST00000468021;ENST00000485979;ENST00000465024;ENST00000478157","GO:0005737(cytoplasm);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0005856(cytoskeleton);GO:0042995(cell projection);GO:0005515(protein binding);GO:0006915(apoptotic process);GO:0005813(centrosome);GO:0035735(intraciliary transport involved in cilium assembly);GO:0005929(cilium);GO:0030992(intraciliary transport particle B);GO:0097542(ciliary tip);GO:0060271(cilium assembly);GO:0005794(Golgi apparatus);GO:0036064(ciliary basal body);GO:0006919(activation of cysteine-type endopeptidase activity involved in apoptotic process);GO:0042981(regulation of apoptotic process);GO:0042073(intraciliary transport);GO:0001843(neural tube closure);GO:0001947(heart looping);GO:0007224(smoothened signaling pathway);GO:0044458(motile cilium assembly);GO:0050680(negative regulation of epithelial cell proliferation);GO:0060972(left/right pattern formation);GO:1905515(non-motile cilium assembly);GO:0005930(axoneme);GO:0032391(photoreceptor connecting cilium);GO:0044292(dendrite terminus);GO:0044292(dendrite terminus)","05016(Huntington's disease);05016(Huntington's disease)","K04638","NA","intraflagellar transport 57 [Source:HGNC Symbol;Acc:HGNC:17367]",{"v":2.77101675942645,"d":"2.77"},{"v":4.04236590467339,"d":"4.04"},{"v":0.685493798624927,"d":"0.69"},{"v":-0.544784480281159,"d":"-0.54"},{"v":0.219840353246984,"d":"0.22"},{"v":0.76732160089695,"d":"0.77"},"down","no"]
["ENSG00000176681","LRRC37A","ENST00000320254;ENST00000496930;ENST00000393465","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016021(integral component of membrane)","NA","NA","NA","leucine rich repeat containing 37A [Source:HGNC Symbol;Acc:HGNC:29069]",{"v":1.04406742775899,"d":"1.04"},{"v":0.489019069166923,"d":"0.49"},{"v":2.13502395630017,"d":"2.14"},{"v":1.09425225787459,"d":"1.09"},{"v":0.221305778174623,"d":"0.22"},{"v":0.769331104885368,"d":"0.77"},"up","no"]
["MSTRG.5523","MSRB1","ENST00000361871;ENST00000622125;ENST00000399753;ENST00000489198;ENST00000473663;ENST00000564908","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0003779(actin binding);GO:0005856(cytoskeleton);GO:0002376(immune system process);GO:0045087(innate immune response);GO:0006979(response to oxidative stress);GO:0016671(oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor);GO:0033743(peptide-methionine (R)-S-oxide reductase activity);GO:0030091(protein repair);GO:0005575(cellular_component);GO:0005829(cytosol);GO:0030041(actin filament polymerization);GO:0015629(actin cytoskeleton);GO:0008270(zinc ion binding);GO:0070191(methionine-R-sulfoxide reductase activity);GO:0005654(nucleoplasm);GO:0005654(nucleoplasm)","NA","NA","NA","methionine sulfoxide reductase B1 [Source:HGNC Symbol;Acc:HGNC:14133]",{"v":43.5170737315716,"d":"43.52"},{"v":62.9091796124247,"d":"62.91"},{"v":0.691744416310539,"d":"0.69"},{"v":-0.531689001290451,"d":"-0.53"},{"v":0.223508763947165,"d":"0.22"},{"v":0.772502165392389,"d":"0.77"},"down","no"]
["ENSG00000114767","RRP9","ENST00000232888","GO:0003723(RNA binding);GO:0005634(nucleus);GO:0030529(intracellular ribonucleoprotein complex);GO:0005730(nucleolus);GO:0006364(rRNA processing);GO:0032040(small-subunit processome);GO:0005654(nucleoplasm);GO:0034511(U3 snoRNA binding);GO:0031428(box C/D snoRNP complex)","NA","NA","NA","ribosomal RNA processing 9, U3 small nucleolar RNA binding protein [Source:HGNC Symbol;Acc:HGNC:16829]",{"v":3.116144,"d":"3.12"},{"v":4.52956,"d":"4.53"},{"v":0.687957329188707,"d":"0.69"},{"v":-0.539609010885824,"d":"-0.54"},{"v":0.225274859085817,"d":"0.23"},{"v":0.774916154787796,"d":"0.77"},"down","no"]
["MSTRG.4397","ERO1A","ENST00000395686;ENST00000553714;ENST00000555069;ENST00000554251;ENST00000554019;ENST00000556358;ENST00000556769","GO:0016020(membrane);GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005515(protein binding);GO:0006915(apoptotic process);GO:0016671(oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor);GO:0003756(protein disulfide isomerase activity);GO:0005788(endoplasmic reticulum lumen);GO:0006464(cellular protein modification process);GO:0034976(response to endoplasmic reticulum stress);GO:0034599(cellular response to oxidative stress);GO:0070059(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress);GO:0043231(intracellular membrane-bounded organelle);GO:0009266(response to temperature stimulus);GO:0015035(protein disulfide oxidoreductase activity);GO:0006457(protein folding);GO:0051209(release of sequestered calcium ion into cytosol);GO:0034975(protein folding in endoplasmic reticulum);GO:0051085(chaperone mediated protein folding requiring cofactor);GO:0015036(disulfide oxidoreductase activity);GO:0010260(animal organ senescence);GO:0019471(4-hydroxyproline metabolic process);GO:0022417(protein maturation by protein folding);GO:0030198(extracellular matrix organization);GO:0030968(endoplasmic reticulum unfolded protein response);GO:0045454(cell redox homeostasis);GO:0050873(brown fat cell differentiation);GO:0071456(cellular response to hypoxia);GO:0030425(dendrite);GO:0030425(dendrite)","04141(Protein processing in endoplasmic reticulum);05110(Vibrio cholerae infection);05110(Vibrio cholerae infection)","K10950","EC:1.8.4.-","endoplasmic reticulum oxidoreductase 1 alpha [Source:HGNC Symbol;Acc:HGNC:13280]",{"v":7.55996629795972,"d":"7.56"},{"v":3.60845298569157,"d":"3.61"},{"v":2.09507130283723,"d":"2.10"},{"v":1.06699934487888,"d":"1.07"},{"v":0.226115788747478,"d":"0.23"},{"v":0.775053912256333,"d":"0.78"},"up","no"]
["MSTRG.6321","CYB5D2","ENST00000301391;ENST00000575251;ENST00000575411;ENST00000577075","GO:0005576(extracellular region);GO:0007399(nervous system development);GO:0012505(endomembrane system);GO:0016020(membrane);GO:0020037(heme binding);GO:0045666(positive regulation of neuron differentiation);GO:0045666(positive regulation of neuron differentiation)","NA","NA","NA","cytochrome b5 domain containing 2 [Source:HGNC Symbol;Acc:HGNC:28471]",{"v":2.05218548487626,"d":"2.05"},{"v":0.964625978001833,"d":"0.96"},{"v":2.12744165269864,"d":"2.13"},{"v":1.0891195650409,"d":"1.09"},{"v":0.227332749841555,"d":"0.23"},{"v":0.775382552618496,"d":"0.78"},"up","no"]
["MSTRG.13567","HERPUD2","ENST00000396081;ENST00000311350;ENST00000438224;ENST00000427455;ENST00000413517;ENST00000603731","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0007283(spermatogenesis);GO:0006986(response to unfolded protein);GO:0006986(response to unfolded protein)","NA","NA","NA","HERPUD family member 2 [Source:HGNC Symbol;Acc:HGNC:21915]",{"v":13.5192779679606,"d":"13.52"},{"v":6.45732466697474,"d":"6.46"},{"v":2.09363454142292,"d":"2.09"},{"v":1.06600963171891,"d":"1.07"},{"v":0.227817440571069,"d":"0.23"},{"v":0.775382552618496,"d":"0.78"},"up","no"]
["MSTRG.3952","ALG5","ENST00000239891;ENST00000443765;ENST00000496689;ENST00000486410;ENST00000460230","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016740(transferase activity);GO:0016757(transferase activity, transferring glycosyl groups);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0006486(protein glycosylation);GO:0006487(protein N-linked glycosylation);GO:0018279(protein N-linked glycosylation via asparagine);GO:0004576(oligosaccharyl transferase activity);GO:0004581(dolichyl-phosphate beta-glucosyltransferase activity);GO:0007368(determination of left/right symmetry);GO:0007368(determination of left/right symmetry)","00510(N-Glycan biosynthesis);00510(N-Glycan biosynthesis)","K00729","EC:2.4.1.117","ALG5, dolichyl-phosphate beta-glucosyltransferase [Source:HGNC Symbol;Acc:HGNC:20266]",{"v":3.10848053828624,"d":"3.11"},{"v":4.50522174794895,"d":"4.51"},{"v":0.689972816477104,"d":"0.69"},{"v":-0.535388571121499,"d":"-0.54"},{"v":0.229270666260261,"d":"0.23"},{"v":0.775382552618496,"d":"0.78"},"down","no"]
["ENSG00000165983","PTER","ENST00000378000;ENST00000423462;ENST00000535784;ENST00000298942","GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0016787(hydrolase activity);GO:0016788(hydrolase activity, acting on ester bonds);GO:0009056(catabolic process);GO:0003674(molecular_function);GO:0070062(extracellular exosome);GO:0030855(epithelial cell differentiation);GO:0030855(epithelial cell differentiation)","NA","NA","NA","phosphotriesterase related [Source:HGNC Symbol;Acc:HGNC:9590]",{"v":1.47265410092431,"d":"1.47"},{"v":0.693544243817137,"d":"0.69"},{"v":2.12337441201891,"d":"2.12"},{"v":1.08635878232998,"d":"1.09"},{"v":0.229861373991202,"d":"0.23"},{"v":0.775382552618496,"d":"0.78"},"up","no"]
["ENSG00000256977","LIMS3","ENST00000480744;ENST00000631420;ENST00000437679;ENST00000482065;ENST00000479168","GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0016020(membrane);GO:0005886(plasma membrane);GO:0030054(cell junction);GO:0045216(cell-cell junction organization);GO:0005925(focal adhesion);GO:0005925(focal adhesion)","NA","NA","NA","LIM zinc finger domain containing 3 [Source:HGNC Symbol;Acc:HGNC:30047]",{"v":1.69035226974396,"d":"1.69"},{"v":0.799729653804544,"d":"0.80"},{"v":2.11365461028295,"d":"2.11"},{"v":1.07973964694652,"d":"1.08"},{"v":0.230646863350386,"d":"0.23"},{"v":0.775382552618496,"d":"0.78"},"up","no"]
["ENSG00000163933","RFT1","ENST00000296292;ENST00000471158","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0006869(lipid transport);GO:0008643(carbohydrate transport);GO:0005319(lipid transporter activity);GO:0005789(endoplasmic reticulum membrane);GO:0034203(glycolipid translocation);GO:0034203(glycolipid translocation)","NA","NA","NA","RFT1 homolog [Source:HGNC Symbol;Acc:HGNC:30220]",{"v":1.89322460641399,"d":"1.89"},{"v":0.905301497813411,"d":"0.91"},{"v":2.09126419318506,"d":"2.09"},{"v":1.06437533171286,"d":"1.06"},{"v":0.232131365999508,"d":"0.23"},{"v":0.77725650656341,"d":"0.78"},"up","no"]
["ENSG00000179583","CIITA","ENST00000618327;ENST00000324288;ENST00000570546;ENST00000573309;ENST00000618207;ENST00000572665;ENST00000576601;ENST00000571186;ENST00000575513;ENST00000571190;ENST00000637439;ENST00000381835;ENST00000636238","GO:0005524(ATP binding);GO:0006355(regulation of transcription, DNA-templated);GO:0000166(nucleotide binding);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0032966(negative regulation of collagen biosynthetic process);GO:0005634(nucleus);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0006351(transcription, DNA-templated);GO:0016746(transferase activity, transferring acyl groups);GO:0005525(GTP binding);GO:0005515(protein binding);GO:0005654(nucleoplasm);GO:0008022(protein C-terminus binding);GO:0003713(transcription coactivator activity);GO:0006955(immune response);GO:0045893(positive regulation of transcription, DNA-templated);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0045892(negative regulation of transcription, DNA-templated);GO:0016605(PML body);GO:0044212(transcription regulatory region DNA binding);GO:0032403(protein complex binding);GO:0060333(interferon-gamma-mediated signaling pathway);GO:0034341(response to interferon-gamma);GO:0046677(response to antibiotic);GO:0033613(activating transcription factor binding);GO:0045345(positive regulation of MHC class I biosynthetic process);GO:0045348(positive regulation of MHC class II biosynthetic process);GO:0006954(inflammatory response);GO:0007568(aging);GO:0071257(cellular response to electrical stimulus);GO:0071346(cellular response to interferon-gamma);GO:0071360(cellular response to exogenous dsRNA);GO:0009986(cell surface);GO:0009986(cell surface)","04612(Antigen processing and presentation);05340(Primary immunodeficiency);05152(Tuberculosis);05164(Influenza A);05145(Toxoplasmosis);05145(Toxoplasmosis)","K08060","NA","class II major histocompatibility complex transactivator [Source:HGNC Symbol;Acc:HGNC:7067]",{"v":2.48559572922844,"d":"2.49"},{"v":1.19378968489278,"d":"1.19"},{"v":2.08210521558635,"d":"2.08"},{"v":1.05804297457838,"d":"1.06"},{"v":0.232688719726204,"d":"0.23"},{"v":0.777331750043466,"d":"0.78"},"up","no"]
["MSTRG.3385","KRT1","MSTRG.3385.1;ENST00000252244","GO:0005634(nucleus);GO:0016020(membrane);GO:0030246(carbohydrate binding);GO:0005198(structural molecule activity);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0005882(intermediate filament);GO:0005615(extracellular space);GO:0005576(extracellular region);GO:0045095(keratin filament);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0031424(keratinization);GO:0031012(extracellular matrix);GO:0001895(retina homeostasis);GO:0072562(blood microparticle);GO:0004872(receptor activity);GO:0043312(neutrophil degranulation);GO:0001867(complement activation, lectin pathway);GO:0006979(response to oxidative stress);GO:1904813(ficolin-1-rich granule lumen);GO:0005856(cytoskeleton);GO:0070268(cornification);GO:0045765(regulation of angiogenesis);GO:0042730(fibrinolysis);GO:0030280(structural constituent of epidermis);GO:0018149(peptide cross-linking);GO:0050728(negative regulation of inflammatory response);GO:0061436(establishment of skin barrier);GO:0098773(skin epidermis development);GO:0001533(cornified envelope)","NA","NA","NA","keratin 1 [Source:HGNC Symbol;Acc:HGNC:6412]",{"v":1.65215181161092,"d":"1.65"},{"v":2.38291420915033,"d":"2.38"},{"v":0.693332477210761,"d":"0.69"},{"v":-0.528380753784431,"d":"-0.53"},{"v":0.233563710847942,"d":"0.23"},{"v":0.778076699391036,"d":"0.78"},"down","no"]
["MSTRG.11630","TMEM165","ENST00000381334;ENST00000514904;ENST00000508404;ENST00000608091;ENST00000506103;ENST00000515591;ENST00000502797;ENST00000509575;ENST00000506198;ENST00000511710;ENST00000508561;ENST00000514070","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005794(Golgi apparatus);GO:0043231(intracellular membrane-bounded organelle);GO:0005765(lysosomal membrane);GO:0000139(Golgi membrane);GO:0005764(lysosome);GO:0005768(endosome);GO:0031902(late endosome membrane);GO:0010008(endosome membrane);GO:0031901(early endosome membrane);GO:0032588(trans-Golgi network membrane);GO:0006487(protein N-linked glycosylation);GO:0006874(cellular calcium ion homeostasis);GO:0032472(Golgi calcium ion transport);GO:0035751(regulation of lysosomal lumen pH);GO:0035751(regulation of lysosomal lumen pH)","NA","NA","NA","transmembrane protein 165 [Source:HGNC Symbol;Acc:HGNC:30760]",{"v":2.8260709246274,"d":"2.83"},{"v":4.03499916224273,"d":"4.03"},{"v":0.700389469983586,"d":"0.70"},{"v":-0.513770701173943,"d":"-0.51"},{"v":0.235440774844103,"d":"0.24"},{"v":0.778745006626194,"d":"0.78"},"down","no"]
["MSTRG.1128","AL591806.3;TSTD1;F11R","MSTRG.1128.1;ENST00000423014;ENST00000368026;ENST00000368023;ENST00000368024;ENST00000486084;ENST00000318289;ENST00000462952;ENST00000466967;ENST00000621309;ENST00000602966;ENST00000472573;ENST00000335772;ENST00000470694","GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0048471(perinuclear region of cytoplasm);GO:0000932(P-body);GO:0005739(mitochondrion);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0030054(cell junction);GO:0050900(leukocyte migration);GO:0046718(viral entry into host cell);GO:0005923(bicellular tight junction);GO:0045296(cadherin binding);GO:0070062(extracellular exosome);GO:0043547(positive regulation of GTPase activity);GO:0016032(viral process);GO:0006954(inflammatory response);GO:0030198(extracellular matrix organization);GO:0005911(cell-cell junction);GO:0030165(PDZ domain binding);GO:0090002(establishment of protein localization to plasma membrane);GO:2000249(regulation of actin cytoskeleton reorganization);GO:0001618(virus receptor activity);GO:0007179(transforming growth factor beta receptor signaling pathway);GO:0050892(intestinal absorption);GO:0034260(negative regulation of GTPase activity);GO:0031032(actomyosin structure organization);GO:0070830(bicellular tight junction assembly);GO:0090557(establishment of endothelial intestinal barrier);GO:0001817(regulation of cytokine production);GO:0007155(cell adhesion);GO:0009314(response to radiation);GO:0030154(cell differentiation);GO:0030855(epithelial cell differentiation);GO:0045777(positive regulation of blood pressure);GO:0090559(regulation of membrane permeability);GO:0031410(cytoplasmic vesicle);GO:0036057(slit diaphragm);GO:0036057(slit diaphragm)","04514(Cell adhesion molecules (CAMs));04530(Tight junction);04670(Leukocyte transendothelial migration);05120(Epithelial cell signaling in Helicobacter pylori infection);05120(Epithelial cell signaling in Helicobacter pylori infection)","K06089","NA","thiosulfate sulfurtransferase like domain containing 1 [Source:HGNC Symbol;Acc:HGNC:35410];F11 receptor [Source:HGNC Symbol;Acc:HGNC:14685]",{"v":10.3606060279856,"d":"10.36"},{"v":4.99860941304999,"d":"5.00"},{"v":2.07269765886027,"d":"2.07"},{"v":1.05150968814328,"d":"1.05"},{"v":0.23604762672206,"d":"0.24"},{"v":0.779198717772394,"d":"0.78"},"up","no"]
["ENSG00000171793","CTPS1","ENST00000372621;ENST00000470271;ENST00000486889;ENST00000463423;ENST00000475060;ENST00000372616;ENST00000479480;ENST00000498694","GO:0016020(membrane);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0016874(ligase activity);GO:0006221(pyrimidine nucleotide biosynthetic process);GO:0006241(CTP biosynthetic process);GO:0002376(immune system process);GO:0003883(CTP synthase activity);GO:0006541(glutamine metabolic process);GO:0044210('de novo' CTP biosynthetic process);GO:0042802(identical protein binding);GO:0005829(cytosol);GO:0006139(nucleobase-containing compound metabolic process);GO:0015949(nucleobase-containing small molecule interconversion);GO:0042098(T cell proliferation);GO:0042493(response to drug);GO:0042100(B cell proliferation);GO:0042100(B cell proliferation)","00240(Pyrimidine metabolism);00240(Pyrimidine metabolism)","K01937","EC:6.3.4.2","CTP synthase 1 [Source:HGNC Symbol;Acc:HGNC:2519]",{"v":1.03400548279019,"d":"1.03"},{"v":1.47639431545222,"d":"1.48"},{"v":0.70035861826891,"d":"0.70"},{"v":-0.513834252380826,"d":"-0.51"},{"v":0.237478479793605,"d":"0.24"},{"v":0.780376170112831,"d":"0.78"},"down","no"]
["MSTRG.2078","RIC8A;MIR6743","ENST00000526104;ENST00000527696;ENST00000530149;ENST00000530889;ENST00000529275;ENST00000526982;ENST00000527039;ENST00000527468;ENST00000526557;ENST00000531541;ENST00000528357;ENST00000325207;ENST00000532241;ENST00000611346;ENST00000524854","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005886(plasma membrane);GO:0043547(positive regulation of GTPase activity);GO:0005515(protein binding);GO:0005085(guanyl-nucleotide exchange factor activity);GO:0005096(GTPase activator activity);GO:0007186(G-protein coupled receptor signaling pathway);GO:0001965(G-protein alpha-subunit binding);GO:0001701(in utero embryonic development);GO:0001944(vasculature development);GO:0007193(adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway);GO:0007369(gastrulation);GO:0008542(visual learning);GO:0009416(response to light stimulus);GO:0042074(cell migration involved in gastrulation);GO:0070586(cell-cell adhesion involved in gastrulation);GO:0071711(basement membrane organization);GO:0071711(basement membrane organization)","NA","NA","NA","RIC8 guanine nucleotide exchange factor A [Source:HGNC Symbol;Acc:HGNC:29550];microRNA 6743 [Source:HGNC Symbol;Acc:HGNC:50008]",{"v":4.18599784876589,"d":"4.19"},{"v":5.96028977187734,"d":"5.96"},{"v":0.702314486204486,"d":"0.70"},{"v":-0.509810901835268,"d":"-0.51"},{"v":0.238672959230981,"d":"0.24"},{"v":0.78220041501235,"d":"0.78"},"down","no"]
["ENSG00000152465","NMT2","ENST00000378165;ENST00000378150;ENST00000466201;ENST00000486786","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005794(Golgi apparatus);GO:0005829(cytosol);GO:0016740(transferase activity);GO:0016746(transferase activity, transferring acyl groups);GO:0005886(plasma membrane);GO:0075733(intracellular transport of virus);GO:0043657(host cell);GO:0019898(extrinsic component of membrane);GO:0004379(glycylpeptide N-tetradecanoyltransferase activity);GO:0006499(N-terminal protein myristoylation);GO:0022400(regulation of rhodopsin mediated signaling pathway);GO:0018008(N-terminal peptidyl-glycine N-myristoylation);GO:0018008(N-terminal peptidyl-glycine N-myristoylation)","NA","NA","NA","N-myristoyltransferase 2 [Source:HGNC Symbol;Acc:HGNC:7858]",{"v":1.42243723723404,"d":"1.42"},{"v":2.03046842553191,"d":"2.03"},{"v":0.700546346521696,"d":"0.70"},{"v":-0.51344759571566,"d":"-0.51"},{"v":0.240376577929505,"d":"0.24"},{"v":0.783206925522076,"d":"0.78"},"down","no"]
["ENSG00000178802","MPI","ENST00000352410;ENST00000565576;ENST00000563422;ENST00000568303;ENST00000569233;ENST00000567116;ENST00000567132;ENST00000562800;ENST00000567570;ENST00000566556;ENST00000535694;ENST00000563786;ENST00000566377;ENST00000561470;ENST00000568840","GO:0008270(zinc ion binding);GO:0016853(isomerase activity);GO:0005975(carbohydrate metabolic process);GO:0009298(GDP-mannose biosynthetic process);GO:0004476(mannose-6-phosphate isomerase activity);GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0006486(protein glycosylation);GO:0000032(cell wall mannoprotein biosynthetic process);GO:0061611(mannose to fructose-6-phosphate metabolic process);GO:0061611(mannose to fructose-6-phosphate metabolic process)","00051(Fructose and mannose metabolism);00520(Amino sugar and nucleotide sugar metabolism);00520(Amino sugar and nucleotide sugar metabolism)","K01809","EC:5.3.1.8","mannose phosphate isomerase [Source:HGNC Symbol;Acc:HGNC:7216]",{"v":0.684438031133113,"d":"0.68"},{"v":0.979954562926293,"d":"0.98"},{"v":0.69843853687387,"d":"0.70"},{"v":-0.517794931935196,"d":"-0.52"},{"v":0.240605346232427,"d":"0.24"},{"v":0.783206925522076,"d":"0.78"},"down","no"]
["MSTRG.6861","TMEM101","ENST00000206380;ENST00000587529;ENST00000585950;ENST00000589334;ENST00000591162","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0004871(signal transducer activity);GO:0007165(signal transduction);GO:0005575(cellular_component);GO:0043123(positive regulation of I-kappaB kinase/NF-kappaB signaling);GO:0043123(positive regulation of I-kappaB kinase/NF-kappaB signaling)","NA","NA","NA","transmembrane protein 101 [Source:HGNC Symbol;Acc:HGNC:28653]",{"v":4.41474811620997,"d":"4.41"},{"v":6.25989187982833,"d":"6.26"},{"v":0.705243509146845,"d":"0.71"},{"v":-0.503806612154858,"d":"-0.50"},{"v":0.242078651492599,"d":"0.24"},{"v":0.783206925522076,"d":"0.78"},"down","no"]
["MSTRG.10535","FAM109B","ENST00000321753","GO:0005829(cytosol);GO:0005794(Golgi apparatus);GO:0042803(protein homodimerization activity);GO:0005515(protein binding);GO:0031410(cytoplasmic vesicle);GO:0005768(endosome);GO:0005802(trans-Golgi network);GO:0005769(early endosome);GO:0042147(retrograde transport, endosome to Golgi);GO:0055037(recycling endosome);GO:0030136(clathrin-coated vesicle);GO:0007032(endosome organization);GO:0001881(receptor recycling)","NA","NA","NA","family with sequence similarity 109 member B [Source:HGNC Symbol;Acc:HGNC:27161]",{"v":0.870998822929417,"d":"0.87"},{"v":1.25434656670747,"d":"1.25"},{"v":0.694384507477625,"d":"0.69"},{"v":-0.526193334942725,"d":"-0.53"},{"v":0.242356450741967,"d":"0.24"},{"v":0.783206925522076,"d":"0.78"},"down","no"]
["ENSG00000205485","AC004980.1","ENST00000418663;ENST00000423084;ENST00000450661","NA","NA","NA","NA",null,{"v":0.524694746302251,"d":"0.52"},{"v":0.242518325080386,"d":"0.24"},{"v":2.1635261835506,"d":"2.16"},{"v":1.11338458073208,"d":"1.11"},{"v":0.243675754866593,"d":"0.24"},{"v":0.783262159877963,"d":"0.78"},"up","no"]
["ENSG00000111110","PPM1H","ENST00000228705;ENST00000551519","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005654(nucleoplasm);GO:0016787(hydrolase activity);GO:0003824(catalytic activity);GO:0006470(protein dephosphorylation);GO:0004721(phosphoprotein phosphatase activity);GO:0004722(protein serine/threonine phosphatase activity);GO:0004722(protein serine/threonine phosphatase activity)","NA","NA","NA","protein phosphatase, Mg2+/Mn2+ dependent 1H [Source:HGNC Symbol;Acc:HGNC:18583]",{"v":0.570812635140875,"d":"0.57"},{"v":0.272135607673793,"d":"0.27"},{"v":2.09753012485269,"d":"2.10"},{"v":1.06869153088607,"d":"1.07"},{"v":0.244922485526062,"d":"0.24"},{"v":0.783765451753693,"d":"0.78"},"up","no"]
["MSTRG.106","CAMTA1","ENST00000461311;ENST00000473578;ENST00000476163;ENST00000303635;ENST00000476864;ENST00000482934;ENST00000486138;ENST00000557126;ENST00000467404;ENST00000461580;ENST00000467267;ENST00000490738","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005730(nucleolus);GO:0005829(cytosol);GO:0006366(transcription from RNA polymerase II promoter);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0001077(transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0043565(sequence-specific DNA binding);GO:0050885(neuromuscular process controlling balance);GO:0050885(neuromuscular process controlling balance)","NA","NA","NA","calmodulin binding transcription activator 1 [Source:HGNC Symbol;Acc:HGNC:18806]",{"v":0.748675812917373,"d":"0.75"},{"v":1.06669465912489,"d":"1.07"},{"v":0.701865155612181,"d":"0.70"},{"v":-0.510734212528658,"d":"-0.51"},{"v":0.245258318084484,"d":"0.25"},{"v":0.784407834732887,"d":"0.78"},"down","no"]
["ENSG00000183426","NPIPA1","ENST00000472413;ENST00000541836;ENST00000545831;ENST00000328085;ENST00000534720;ENST00000545479;ENST00000537062;ENST00000424549","GO:0006810(transport);GO:0051028(mRNA transport);GO:0005634(nucleus);GO:0016020(membrane);GO:0015031(protein transport);GO:0005654(nucleoplasm);GO:0005643(nuclear pore);GO:0031965(nuclear membrane);GO:0016021(integral component of membrane);GO:0016021(integral component of membrane)","NA","NA","NA","nuclear pore complex interacting protein family member A1 [Source:HGNC Symbol;Acc:HGNC:7909]",{"v":1.19099295231551,"d":"1.19"},{"v":0.575658642022812,"d":"0.58"},{"v":2.06892221426655,"d":"2.07"},{"v":1.04887940488788,"d":"1.05"},{"v":0.248013628528245,"d":"0.25"},{"v":0.787881159418055,"d":"0.79"},"up","no"]
["MSTRG.1538","PRKCQ-AS1","ENST00000455810;ENST00000613651;ENST00000445427;ENST00000607996;ENST00000607982;ENST00000625147;ENST00000608453;ENST00000615210;ENST00000624974;ENST00000624678;ENST00000609627;ENST00000414894;ENST00000449648;ENST00000625102;ENST00000609346;ENST00000613985","NA","NA","NA","NA","PRKCQ antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:44689]",{"v":1.95974874177801,"d":"1.96"},{"v":2.77804607965057,"d":"2.78"},{"v":0.705441409389621,"d":"0.71"},{"v":-0.503401830481835,"d":"-0.50"},{"v":0.248377312718219,"d":"0.25"},{"v":0.787881159418055,"d":"0.79"},"down","no"]
["MSTRG.15510","UBL4A","ENST00000369660;ENST00000417913;ENST00000477777;ENST00000481237;ENST00000369653","GO:0006810(transport);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005515(protein binding);GO:0006464(cellular protein modification process);GO:0051087(chaperone binding);GO:0016020(membrane);GO:0019787(ubiquitin-like protein transferase activity);GO:0071816(tail-anchored membrane protein insertion into ER membrane);GO:0071818(BAT3 complex);GO:0071818(BAT3 complex)","NA","NA","NA","ubiquitin like 4A [Source:HGNC Symbol;Acc:HGNC:12505]",{"v":11.5289313714829,"d":"11.53"},{"v":16.1876155395437,"d":"16.19"},{"v":0.71220689318446,"d":"0.71"},{"v":-0.489631695812461,"d":"-0.49"},{"v":0.249484298549097,"d":"0.25"},{"v":0.788155919219441,"d":"0.79"},"down","no"]
["MSTRG.15422","NDUFA1","ENST00000371437","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005829(cytosol);GO:0055114(oxidation-reduction process);GO:0005739(mitochondrion);GO:0005743(mitochondrial inner membrane);GO:0070469(respiratory chain);GO:0031966(mitochondrial membrane);GO:0032981(mitochondrial respiratory chain complex I assembly);GO:0008137(NADH dehydrogenase (ubiquinone) activity);GO:0006120(mitochondrial electron transport, NADH to ubiquinone);GO:0005747(mitochondrial respiratory chain complex I)","00190(Oxidative phosphorylation);04723(Retrograde endocannabinoid signaling);05010(Alzheimer's disease);05012(Parkinson's disease);05016(Huntington's disease);04932(Non-alcoholic fatty liver disease (NAFLD))","K03945","NA","NADH:ubiquinone oxidoreductase subunit A1 [Source:HGNC Symbol;Acc:HGNC:7683]",{"v":14.596061,"d":"14.60"},{"v":20.478096,"d":"20.48"},{"v":0.712764555845426,"d":"0.71"},{"v":-0.488502498175433,"d":"-0.49"},{"v":0.251332131280357,"d":"0.25"},{"v":0.789696980670669,"d":"0.79"},"down","no"]
["MSTRG.1867","SRP9P1","ENST00000445874","NA","NA","NA","NA","signal recognition particle 9 pseudogene 1 [Source:HGNC Symbol;Acc:HGNC:23402]",{"v":10.075666,"d":"10.08"},{"v":14.302627,"d":"14.30"},{"v":0.7044626137562,"d":"0.70"},{"v":-0.505404950992244,"d":"-0.51"},{"v":0.252253893453654,"d":"0.25"},{"v":0.790881334956069,"d":"0.79"},"down","no"]
["MSTRG.10023","CBR1","ENST00000290349;ENST00000530908;ENST00000466328;ENST00000439427","GO:0005737(cytoplasm);GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0030855(epithelial cell differentiation);GO:1903561(extracellular vesicle);GO:0019371(cyclooxygenase pathway);GO:0016655(oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor);GO:0004090(carbonyl reductase (NADPH) activity);GO:0017144(drug metabolic process);GO:0047021(15-hydroxyprostaglandin dehydrogenase (NADP+) activity);GO:0050221(prostaglandin-E2 9-reductase activity);GO:0042373(vitamin K metabolic process);GO:0042373(vitamin K metabolic process)","00590(Arachidonic acid metabolism);00790(Folate biosynthesis);00980(Metabolism of xenobiotics by cytochrome P450);05204(Chemical carcinogenesis);05204(Chemical carcinogenesis)","K00079","EC:1.1.1.184;EC:1.1.1.189","carbonyl reductase 1 [Source:HGNC Symbol;Acc:HGNC:1548]",{"v":5.00281060040816,"d":"5.00"},{"v":7.00986872285714,"d":"7.01"},{"v":0.713681068533488,"d":"0.71"},{"v":-0.486648591557006,"d":"-0.49"},{"v":0.254097147411864,"d":"0.25"},{"v":0.793233917444618,"d":"0.79"},"down","no"]
["ENSG00000160050","CCDC28B","ENST00000373602;ENST00000469003;ENST00000461819;ENST00000421922;ENST00000483009","GO:0005737(cytoplasm);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0005813(centrosome);GO:0005815(microtubule organizing center);GO:0060271(cilium assembly);GO:0030030(cell projection organization);GO:0030030(cell projection organization)","NA","NA","NA","coiled-coil domain containing 28B [Source:HGNC Symbol;Acc:HGNC:28163]",{"v":0.936654255500355,"d":"0.94"},{"v":1.33583404293825,"d":"1.34"},{"v":0.701175614180431,"d":"0.70"},{"v":-0.512152272652903,"d":"-0.51"},{"v":0.25516450554814,"d":"0.26"},{"v":0.794380983821232,"d":"0.79"},"down","no"]
["MSTRG.10618","CRBN","ENST00000491834;ENST00000231948;ENST00000498700;ENST00000488263;ENST00000459840;ENST00000478353;ENST00000639284;ENST00000424814;ENST00000492178;ENST00000482844;ENST00000432408;ENST00000629101;ENST00000450014;ENST00000498442","GO:0046872(metal ion binding);GO:0005730(nucleolus);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0016567(protein ubiquitination);GO:0005515(protein binding);GO:0032463(negative regulation of protein homooligomerization);GO:0034766(negative regulation of ion transmembrane transport);GO:0090073(positive regulation of protein homodimerization activity);GO:0043161(proteasome-mediated ubiquitin-dependent protein catabolic process);GO:0031464(Cul4A-RING E3 ubiquitin ligase complex);GO:0031464(Cul4A-RING E3 ubiquitin ligase complex)","NA","NA","NA","cereblon [Source:HGNC Symbol;Acc:HGNC:30185]",{"v":2.92049088200297,"d":"2.92"},{"v":4.07566425247893,"d":"4.08"},{"v":0.716568073591108,"d":"0.72"},{"v":-0.480824328617336,"d":"-0.48"},{"v":0.256271331204073,"d":"0.26"},{"v":0.794380983821232,"d":"0.79"},"down","no"]
["MSTRG.11977","ANKH","ENST00000284268;ENST00000503939;ENST00000503389;ENST00000515517;ENST00000505140;ENST00000513115;MSTRG.11977.2","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005886(plasma membrane);GO:0005887(integral component of plasma membrane);GO:0001501(skeletal system development);GO:0055085(transmembrane transport);GO:0030500(regulation of bone mineralization);GO:0006817(phosphate ion transport);GO:0015114(phosphate ion transmembrane transporter activity);GO:0035435(phosphate ion transmembrane transport);GO:0007626(locomotory behavior);GO:0019867(outer membrane);GO:0005315(inorganic phosphate transmembrane transporter activity);GO:0030504(inorganic diphosphate transmembrane transporter activity);GO:0030505(inorganic diphosphate transport);GO:0030505(inorganic diphosphate transport)","NA","NA","NA","ANKH inorganic pyrophosphate transport regulator [Source:HGNC Symbol;Acc:HGNC:15492]",{"v":3.91556215714416,"d":"3.92"},{"v":1.93351670733037,"d":"1.93"},{"v":2.02509869312194,"d":"2.03"},{"v":1.01799221940861,"d":"1.02"},{"v":0.256939395636011,"d":"0.26"},{"v":0.795254266623182,"d":"0.80"},"up","no"]
["MSTRG.15399","ATG4A","ENST00000372232;ENST00000474825;ENST00000345734;ENST00000457035;ENST00000489247;ENST00000372246","GO:0006810(transport);GO:0005737(cytoplasm);GO:0015031(protein transport);GO:0006914(autophagy);GO:0016787(hydrolase activity);GO:0005515(protein binding);GO:0008233(peptidase activity);GO:0008234(cysteine-type peptidase activity);GO:0006508(proteolysis);GO:0004197(cysteine-type endopeptidase activity);GO:0000045(autophagosome assembly);GO:0000422(mitophagy);GO:0005829(cytosol);GO:0044804(nucleophagy);GO:0006501(C-terminal protein lipidation);GO:0006612(protein targeting to membrane);GO:0051697(protein delipidation);GO:0051697(protein delipidation)","04140(Autophagy - animal);04136(Autophagy - other eukaryotes);04136(Autophagy - other eukaryotes)","K08342","EC:3.4.22.-","autophagy related 4A cysteine peptidase [Source:HGNC Symbol;Acc:HGNC:16489]",{"v":2.59008412606765,"d":"2.59"},{"v":3.6142685022207,"d":"3.61"},{"v":0.716627479246834,"d":"0.72"},{"v":-0.480704729802232,"d":"-0.48"},{"v":0.258427245474453,"d":"0.26"},{"v":0.795254266623182,"d":"0.80"},"down","no"]
["ENSG00000006530","AGK","ENST00000355413;ENST00000494053;ENST00000629555;ENST00000496784;ENST00000495028;ENST00000492693;ENST00000473247","GO:0016020(membrane);GO:0043231(intracellular membrane-bounded organelle);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0005739(mitochondrion);GO:0008152(metabolic process);GO:0003951(NAD+ kinase activity);GO:0004143(diacylglycerol kinase activity);GO:0031966(mitochondrial membrane);GO:0005829(cytosol);GO:0001727(lipid kinase activity);GO:0001729(ceramide kinase activity);GO:0046513(ceramide biosynthetic process);GO:0046834(lipid phosphorylation);GO:0005741(mitochondrial outer membrane);GO:0046474(glycerophospholipid biosynthetic process);GO:0046486(glycerolipid metabolic process);GO:0047620(acylglycerol kinase activity);GO:0047620(acylglycerol kinase activity)","00561(Glycerolipid metabolism);00561(Glycerolipid metabolism)","K09881","EC:2.7.1.94","acylglycerol kinase [Source:HGNC Symbol;Acc:HGNC:21869]",{"v":1.32607825019093,"d":"1.33"},{"v":1.84837686344891,"d":"1.85"},{"v":0.717428505200278,"d":"0.72"},{"v":-0.479093026628327,"d":"-0.48"},{"v":0.258853106676624,"d":"0.26"},{"v":0.795254266623182,"d":"0.80"},"down","no"]
["ENSG00000189190","ZNF600","ENST00000338230;ENST00000598369;ENST00000597124;ENST00000594028;ENST00000599893","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding)","NA","NA","NA","zinc finger protein 600 [Source:HGNC Symbol;Acc:HGNC:30951]",{"v":2.99487669693725,"d":"2.99"},{"v":4.16686700085671,"d":"4.17"},{"v":0.718735850297478,"d":"0.72"},{"v":-0.476466445899994,"d":"-0.48"},{"v":0.260371085869543,"d":"0.26"},{"v":0.795547576638724,"d":"0.80"},"down","no"]
["ENSG00000129354","AP1M2","ENST00000590923;ENST00000250244;ENST00000589571;ENST00000589809;ENST00000592285;ENST00000589684","GO:0006810(transport);GO:0016020(membrane);GO:0006886(intracellular protein transport);GO:0015031(protein transport);GO:0016192(vesicle-mediated transport);GO:0043231(intracellular membrane-bounded organelle);GO:0005794(Golgi apparatus);GO:0030131(clathrin adaptor complex);GO:0005515(protein binding);GO:0031410(cytoplasmic vesicle);GO:0005829(cytosol);GO:0019886(antigen processing and presentation of exogenous peptide antigen via MHC class II);GO:0006903(vesicle targeting);GO:0032588(trans-Golgi network membrane);GO:0030665(clathrin-coated vesicle membrane);GO:0000139(Golgi membrane);GO:0005765(lysosomal membrane);GO:0050690(regulation of defense response to virus by virus);GO:0030659(cytoplasmic vesicle membrane);GO:0030669(clathrin-coated endocytic vesicle membrane);GO:0006605(protein targeting);GO:0006605(protein targeting)","04142(Lysosome);04142(Lysosome)","K12393","NA","adaptor related protein complex 1 mu 2 subunit [Source:HGNC Symbol;Acc:HGNC:558]",{"v":0.560498539295393,"d":"0.56"},{"v":0.799450127371274,"d":"0.80"},{"v":0.701105072230592,"d":"0.70"},{"v":-0.512297422653582,"d":"-0.51"},{"v":0.261433976070954,"d":"0.26"},{"v":0.795547576638724,"d":"0.80"},"down","no"]
["MSTRG.6657","NF1","ENST00000356175;ENST00000358273;ENST00000479536;ENST00000487476;ENST00000577967;ENST00000579081;ENST00000495910;ENST00000581113;ENST00000422121;ENST00000493220;ENST00000488981;ENST00000468273","GO:0005634(nucleus);GO:0016020(membrane);GO:0007165(signal transduction);GO:0005515(protein binding);GO:0005096(GTPase activator activity);GO:0043087(regulation of GTPase activity);GO:0098793(presynapse);GO:0043547(positive regulation of GTPase activity);GO:0005730(nucleolus);GO:0005737(cytoplasm);GO:0008289(lipid binding);GO:0005829(cytosol);GO:0008429(phosphatidylethanolamine binding);GO:0031210(phosphatidylcholine binding);GO:0000165(MAPK cascade);GO:0050890(cognition);GO:0046580(negative regulation of Ras protein signal transduction);GO:0031235(intrinsic component of the cytoplasmic side of the plasma membrane);GO:0007265(Ras protein signal transduction);GO:0048147(negative regulation of fibroblast proliferation);GO:0001937(negative regulation of endothelial cell proliferation);GO:0001649(osteoblast differentiation);GO:0001656(metanephros development);GO:0001666(response to hypoxia);GO:0001889(liver development);GO:0001952(regulation of cell-matrix adhesion);GO:0006469(negative regulation of protein kinase activity);GO:0007154(cell communication);GO:0007406(negative regulation of neuroblast proliferation);GO:0007420(brain development);GO:0007422(peripheral nervous system development);GO:0007507(heart development);GO:0008542(visual learning);GO:0014044(Schwann cell development);GO:0014065(phosphatidylinositol 3-kinase signaling);GO:0021510(spinal cord development);GO:0021897(forebrain astrocyte development);GO:0021987(cerebral cortex development);GO:0022011(myelination in peripheral nervous system);GO:0030036(actin cytoskeleton organization);GO:0030198(extracellular matrix organization);GO:0030199(collagen fibril organization);GO:0030325(adrenal gland development);GO:0030336(negative regulation of cell migration);GO:0042060(wound healing);GO:0042992(negative regulation of transcription factor import into nucleus);GO:0043065(positive regulation of apoptotic process);GO:0043407(negative regulation of MAP kinase activity);GO:0043409(negative regulation of MAPK cascade);GO:0043473(pigmentation);GO:0043525(positive regulation of neuron apoptotic process);GO:0043535(regulation of blood vessel endothelial cell migration);GO:0045124(regulation of bone resorption);GO:0045685(regulation of glial cell differentiation);GO:0045762(positive regulation of adenylate cyclase activity);GO:0045765(regulation of angiogenesis);GO:0048485(sympathetic nervous system development);GO:0048593(camera-type eye morphogenesis);GO:0048715(negative regulation of oligodendrocyte differentiation);GO:0048745(smooth muscle tissue development);GO:0048844(artery morphogenesis);GO:0048853(forebrain morphogenesis);GO:0030424(axon);GO:0030425(dendrite);GO:0001938(positive regulation of endothelial cell proliferation);GO:0001953(negative regulation of cell-matrix adhesion);GO:0007519(skeletal muscle tissue development);GO:0008285(negative regulation of cell proliferation);GO:0008625(extrinsic apoptotic signaling pathway via death domain receptors);GO:0010468(regulation of gene expression);GO:0016525(negative regulation of angiogenesis);GO:0021764(amygdala development);GO:0021915(neural tube development);GO:0032228(regulation of synaptic transmission, GABAergic);GO:0034605(cellular response to heat);GO:0035021(negative regulation of Rac protein signal transduction);GO:0042127(regulation of cell proliferation);GO:0043408(regulation of MAPK cascade);GO:0045671(negative regulation of osteoclast differentiation);GO:0046929(negative regulation of neurotransmitter secretion);GO:0048169(regulation of long-term neuronal synaptic plasticity);GO:0048712(negative regulation of astrocyte differentiation);GO:0048820(hair follicle maturation);GO:0061534(gamma-aminobutyric acid secretion, neurotransmission);GO:0061535(glutamate secretion, neurotransmission);GO:0098597(observational learning);GO:1900271(regulation of long-term synaptic potentiation);GO:1902043(positive regulation of extrinsic apoptotic signaling pathway via death domain receptors);GO:2001241(positive regulation of extrinsic apoptotic signaling pathway in absence of ligand);GO:0016021(integral component of membrane);GO:0016021(integral component of membrane)","04014(Ras signaling pathway);04010(MAPK signaling pathway);01521(EGFR tyrosine kinase inhibitor resistance);01521(EGFR tyrosine kinase inhibitor resistance)","K08052","NA","neurofibromin 1 [Source:HGNC Symbol;Acc:HGNC:7765]",{"v":1.04769118370807,"d":"1.05"},{"v":0.520000107003317,"d":"0.52"},{"v":2.01479032330543,"d":"2.01"},{"v":1.01062970710695,"d":"1.01"},{"v":0.261642165527769,"d":"0.26"},{"v":0.795547576638724,"d":"0.80"},"up","no"]
["ENSG00000159363","ATP13A2","ENST00000452699;ENST00000326735;ENST00000509392;ENST00000511957;ENST00000503552;ENST00000508222;ENST00000341676;ENST00000463860;ENST00000506174;ENST00000510069;ENST00000466561;ENST00000509619","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0016787(hydrolase activity);GO:0005765(lysosomal membrane);GO:0005515(protein binding);GO:0006812(cation transport);GO:0099132(ATP hydrolysis coupled cation transmembrane transport);GO:0070588(calcium ion transmembrane transport);GO:0016887(ATPase activity);GO:0005764(lysosome);GO:0005887(integral component of plasma membrane);GO:0034220(ion transmembrane transport);GO:0005776(autophagosome);GO:1903146(regulation of mitophagy);GO:0080025(phosphatidylinositol-3,5-bisphosphate binding);GO:0043202(lysosomal lumen);GO:0043005(neuron projection);GO:0050714(positive regulation of protein secretion);GO:0031982(vesicle);GO:0016241(regulation of macroautophagy);GO:0034599(cellular response to oxidative stress);GO:1901215(negative regulation of neuron death);GO:0008270(zinc ion binding);GO:0010821(regulation of mitochondrion organization);GO:0055069(zinc ion homeostasis);GO:0071287(cellular response to manganese ion);GO:0043025(neuronal cell body);GO:0046777(protein autophosphorylation);GO:1905165(regulation of lysosomal protein catabolic process);GO:1904714(regulation of chaperone-mediated autophagy);GO:0005388(calcium-transporting ATPase activity);GO:0030133(transport vesicle);GO:0019829(cation-transporting ATPase activity);GO:1903135(cupric ion binding);GO:0030145(manganese ion binding);GO:0070300(phosphatidic acid binding);GO:0006874(cellular calcium ion homeostasis);GO:0006879(cellular iron ion homeostasis);GO:0006882(cellular zinc ion homeostasis);GO:0016243(regulation of autophagosome size);GO:0030003(cellular cation homeostasis);GO:0033157(regulation of intracellular protein transport);GO:0052548(regulation of endopeptidase activity);GO:0071294(cellular response to zinc ion);GO:1903543(positive regulation of exosomal secretion);GO:1905037(autophagosome organization);GO:1905122(polyamine import);GO:1905123(regulation of glucosylceramidase activity);GO:1905166(negative regulation of lysosomal protein catabolic process);GO:1990938(peptidyl-aspartic acid autophosphorylation);GO:0005770(late endosome);GO:0005771(multivesicular body);GO:0012506(vesicle membrane);GO:0032585(multivesicular body membrane);GO:1905103(integral component of lysosomal membrane);GO:1905103(integral component of lysosomal membrane)","NA","NA","NA","ATPase 13A2 [Source:HGNC Symbol;Acc:HGNC:30213]",{"v":4.60684809328003,"d":"4.61"},{"v":2.28871024043404,"d":"2.29"},{"v":2.01285772741873,"d":"2.01"},{"v":1.00924520345586,"d":"1.01"},{"v":0.264273559117639,"d":"0.26"},{"v":0.798573292113129,"d":"0.80"},"up","no"]
["ENSG00000167685","ZNF444","ENST00000592949;ENST00000588358;ENST00000337080;ENST00000587195;ENST00000591564;ENST00000586123;ENST00000587467;ENST00000588203;ENST00000593100;ENST00000587236","GO:0005634(nucleus);GO:0006355(regulation of transcription, DNA-templated);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0006351(transcription, DNA-templated);GO:0003676(nucleic acid binding);GO:0046872(metal ion binding);GO:0003677(DNA binding);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0000981(RNA polymerase II transcription factor activity, sequence-specific DNA binding);GO:0000981(RNA polymerase II transcription factor activity, sequence-specific DNA binding)","NA","NA","NA","zinc finger protein 444 [Source:HGNC Symbol;Acc:HGNC:16052]",{"v":0.877488836579638,"d":"0.88"},{"v":0.43494972468573,"d":"0.43"},{"v":2.01744888380758,"d":"2.02"},{"v":1.01253212033748,"d":"1.01"},{"v":0.265153382422224,"d":"0.27"},{"v":0.798656594551684,"d":"0.80"},"up","no"]
["MSTRG.8530","LAPTM4A","ENST00000175091;ENST00000483117","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005794(Golgi apparatus);GO:0012505(endomembrane system);GO:0012505(endomembrane system)","04142(Lysosome);04142(Lysosome)","K12387","NA","lysosomal protein transmembrane 4 alpha [Source:HGNC Symbol;Acc:HGNC:6924]",{"v":23.1754499085303,"d":"23.18"},{"v":31.9442470400822,"d":"31.94"},{"v":0.725496828253638,"d":"0.73"},{"v":-0.462958787794171,"d":"-0.46"},{"v":0.265893998715773,"d":"0.27"},{"v":0.798656594551684,"d":"0.80"},"down","no"]
["MSTRG.15028","CRAT","ENST00000318080;ENST00000458362;ENST00000467343;ENST00000441796;ENST00000464290;ENST00000393384;ENST00000415948","GO:0006810(transport);GO:0016020(membrane);GO:0016740(transferase activity);GO:0005743(mitochondrial inner membrane);GO:0016746(transferase activity, transferring acyl groups);GO:0006629(lipid metabolic process);GO:0005783(endoplasmic reticulum);GO:0006631(fatty acid metabolic process);GO:0005739(mitochondrion);GO:0005777(peroxisome);GO:0005102(receptor binding);GO:0005782(peroxisomal matrix);GO:0033540(fatty acid beta-oxidation using acyl-CoA oxidase);GO:0004092(carnitine O-acetyltransferase activity);GO:0019254(carnitine metabolic process, CoA-linked);GO:0019254(carnitine metabolic process, CoA-linked)","04146(Peroxisome);04146(Peroxisome)","K00624","EC:2.3.1.7","carnitine O-acetyltransferase [Source:HGNC Symbol;Acc:HGNC:2342]",{"v":5.83877760504865,"d":"5.84"},{"v":2.91226676544833,"d":"2.91"},{"v":2.0048910609155,"d":"2.00"},{"v":1.00352384757953,"d":"1.00"},{"v":0.267696499339151,"d":"0.27"},{"v":0.800813870897878,"d":"0.80"},"up","no"]
["MSTRG.10130","MRPL40","ENST00000333130;ENST00000443660;ENST00000471259","GO:0003723(RNA binding);GO:0030529(intracellular ribonucleoprotein complex);GO:0005840(ribosome);GO:0005739(mitochondrion);GO:0005515(protein binding);GO:0005634(nucleus);GO:0009653(anatomical structure morphogenesis);GO:0005743(mitochondrial inner membrane);GO:0070125(mitochondrial translational elongation);GO:0070126(mitochondrial translational termination);GO:0005761(mitochondrial ribosome);GO:0005762(mitochondrial large ribosomal subunit);GO:0005762(mitochondrial large ribosomal subunit)","NA","NA","NA","mitochondrial ribosomal protein L40 [Source:HGNC Symbol;Acc:HGNC:14491]",{"v":2.69935715012723,"d":"2.70"},{"v":3.73293776284987,"d":"3.73"},{"v":0.723118712824838,"d":"0.72"},{"v":-0.467695584163668,"d":"-0.47"},{"v":0.268687929091037,"d":"0.27"},{"v":0.801669656296326,"d":"0.80"},"down","no"]
["ENSG00000071889","FAM3A","ENST00000322269;ENST00000621967;ENST00000447601;ENST00000359889;ENST00000433619;ENST00000369641;ENST00000416319;ENST00000475657;ENST00000492763;ENST00000440318;ENST00000449971;ENST00000426266;ENST00000457212;ENST00000419205;ENST00000369643;ENST00000612856;ENST00000393572;ENST00000497506","GO:0005576(extracellular region);GO:0003674(molecular_function);GO:0005575(cellular_component);GO:0061844(antimicrobial humoral immune response mediated by antimicrobial peptide);GO:0019732(antifungal humoral response);GO:1905035(negative regulation of antifungal innate immune response);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005515(protein binding);GO:0005515(protein binding)","NA","NA","NA","family with sequence similarity 3 member A [Source:HGNC Symbol;Acc:HGNC:13749]",{"v":1.9956914121224,"d":"2.00"},{"v":2.74718705825814,"d":"2.75"},{"v":0.726449043986023,"d":"0.73"},{"v":-0.461066489826065,"d":"-0.46"},{"v":0.270061442111587,"d":"0.27"},{"v":0.802924610148966,"d":"0.80"},"down","no"]
["ENSG00000112139","MDGA1","ENST00000505425;ENST00000373401;ENST00000508399;ENST00000478143;ENST00000434837;ENST00000503419;ENST00000510077","GO:0016020(membrane);GO:0005886(plasma membrane);GO:0007275(multicellular organism development);GO:0005615(extracellular space);GO:0007399(nervous system development);GO:0030154(cell differentiation);GO:0031225(anchored component of membrane);GO:0005576(extracellular region);GO:0003674(molecular_function);GO:0006501(C-terminal protein lipidation);GO:0046658(anchored component of plasma membrane);GO:0001764(neuron migration);GO:0007420(brain development);GO:0021527(spinal cord association neuron differentiation);GO:0021527(spinal cord association neuron differentiation)","NA","NA","NA","MAM domain containing glycosylphosphatidylinositol anchor 1 [Source:HGNC Symbol;Acc:HGNC:19267]",{"v":0.448021399520688,"d":"0.45"},{"v":0.221912802001833,"d":"0.22"},{"v":2.01890740632885,"d":"2.02"},{"v":1.01357474549185,"d":"1.01"},{"v":0.271337980773524,"d":"0.27"},{"v":0.803184390060647,"d":"0.80"},"up","no"]
["MSTRG.13189","SEC63","ENST00000369002;ENST00000446496;ENST00000484803;ENST00000466419;ENST00000465210;ENST00000489455;ENST00000473746;ENST00000459782","GO:0005622(intracellular);GO:0003723(RNA binding);GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0008565(protein transporter activity);GO:0015031(protein transport);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005515(protein binding);GO:0001889(liver development);GO:0006614(SRP-dependent cotranslational protein targeting to membrane);GO:0006620(posttranslational protein targeting to endoplasmic reticulum membrane);GO:0006807(nitrogen compound metabolic process);GO:0010259(multicellular organism aging);GO:0031204(posttranslational protein targeting to membrane, translocation);GO:0072001(renal system development);GO:0005829(cytosol);GO:0004872(receptor activity);GO:0036498(IRE1-mediated unfolded protein response);GO:0006612(protein targeting to membrane);GO:0006612(protein targeting to membrane)","03060(Protein export);04141(Protein processing in endoplasmic reticulum);04141(Protein processing in endoplasmic reticulum)","K09540","NA","SEC63 homolog, protein translocation regulator [Source:HGNC Symbol;Acc:HGNC:21082]",{"v":4.70463973017352,"d":"4.70"},{"v":2.35973435577035,"d":"2.36"},{"v":1.99371582596536,"d":"1.99"},{"v":0.995459790033447,"d":"1.00"},{"v":0.271726429622476,"d":"0.27"},{"v":0.803748057778342,"d":"0.80"},"up","no"]
["ENSG00000153234","NR4A2","ENST00000339562;ENST00000409572;ENST00000424077;ENST00000417972","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016607(nuclear speck);GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0006355(regulation of transcription, DNA-templated);GO:0006366(transcription from RNA polymerase II promoter);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0043565(sequence-specific DNA binding);GO:0005515(protein binding);GO:0003707(steroid hormone receptor activity);GO:0004879(RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding);GO:0030522(intracellular receptor signaling pathway);GO:0043401(steroid hormone mediated signaling pathway);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0005654(nucleoplasm);GO:0045444(fat cell differentiation);GO:0000977(RNA polymerase II regulatory region sequence-specific DNA binding);GO:0000979(RNA polymerase II core promoter sequence-specific DNA binding);GO:0001077(transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0001228(transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding);GO:0035259(glucocorticoid receptor binding);GO:0046982(protein heterodimerization activity);GO:0001666(response to hypoxia);GO:0001764(neuron migration);GO:0001975(response to amphetamine);GO:0007399(nervous system development);GO:0008344(adult locomotory behavior);GO:0009791(post-embryonic development);GO:0010467(gene expression);GO:0010468(regulation of gene expression);GO:0021952(central nervous system projection neuron axonogenesis);GO:0021953(central nervous system neuron differentiation);GO:0021986(habenula development);GO:0030182(neuron differentiation);GO:0031668(cellular response to extracellular stimulus);GO:0034599(cellular response to oxidative stress);GO:0042053(regulation of dopamine metabolic process);GO:0042416(dopamine biosynthetic process);GO:0042417(dopamine metabolic process);GO:0042551(neuron maturation);GO:0043085(positive regulation of catalytic activity);GO:0043524(negative regulation of neuron apoptotic process);GO:0043576(regulation of respiratory gaseous exchange);GO:0045893(positive regulation of transcription, DNA-templated);GO:0051866(general adaptation syndrome);GO:0071376(cellular response to corticotropin-releasing hormone stimulus);GO:0071542(dopaminergic neuron differentiation);GO:0007165(signal transduction);GO:0006367(transcription initiation from RNA polymerase II promoter);GO:0042803(protein homodimerization activity);GO:0060070(canonical Wnt signaling pathway);GO:1904948(midbrain dopaminergic neuron differentiation);GO:0008013(beta-catenin binding);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0046965(retinoid X receptor binding);GO:2001234(negative regulation of apoptotic signaling pathway);GO:2001234(negative regulation of apoptotic signaling pathway)","04925(Aldosterone synthesis and secretion);04925(Aldosterone synthesis and secretion)","K08558","NA","nuclear receptor subfamily 4 group A member 2 [Source:HGNC Symbol;Acc:HGNC:7981]",{"v":0.768941928409377,"d":"0.77"},{"v":0.376333340559617,"d":"0.38"},{"v":2.04324689188032,"d":"2.04"},{"v":1.03086353993544,"d":"1.03"},{"v":0.272852773781173,"d":"0.27"},{"v":0.804021906334215,"d":"0.80"},"up","no"]
["MSTRG.7396","MYL12B","ENST00000237500;ENST00000584539;ENST00000400175;ENST00000581193","GO:0046872(metal ion binding);GO:0005509(calcium ion binding);GO:0016459(myosin complex);GO:0005515(protein binding);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0006936(muscle contraction);GO:0099738(cell cortex region);GO:0032036(myosin heavy chain binding);GO:0008360(regulation of cell shape);GO:0001725(stress fiber);GO:0005903(brush border);GO:0016460(myosin II complex);GO:0030018(Z disc);GO:0045177(apical part of cell);GO:0045177(apical part of cell)","04510(Focal adhesion);04530(Tight junction);04810(Regulation of actin cytoskeleton);04611(Platelet activation);04670(Leukocyte transendothelial migration);04670(Leukocyte transendothelial migration)","K12757","NA","myosin light chain 12B [Source:HGNC Symbol;Acc:HGNC:29827]",{"v":35.8800827200454,"d":"35.88"},{"v":48.9870418949461,"d":"48.99"},{"v":0.73244028077856,"d":"0.73"},{"v":-0.449216960112743,"d":"-0.45"},{"v":0.274181048429897,"d":"0.27"},{"v":0.805456369257477,"d":"0.81"},"down","no"]
["MSTRG.10928","RHOA","ENST00000418115;ENST00000422781;ENST00000445425;ENST00000431929;ENST00000454011;ENST00000265538","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005525(GTP binding);GO:0007264(small GTPase mediated signal transduction);GO:0000166(nucleotide binding);GO:0003924(GTPase activity);GO:0005622(intracellular);GO:0051301(cell division);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0044319(wound healing, spreading of cells);GO:1902766(skeletal muscle satellite cell migration);GO:0005856(cytoskeleton);GO:0042995(cell projection);GO:0005515(protein binding);GO:0007049(cell cycle);GO:0005925(focal adhesion);GO:0030496(midbody);GO:0005789(endoplasmic reticulum membrane);GO:0031234(extrinsic component of cytoplasmic side of plasma membrane);GO:0030027(lamellipodium);GO:0070062(extracellular exosome);GO:0051056(regulation of small GTPase mediated signal transduction);GO:0071902(positive regulation of protein serine/threonine kinase activity);GO:0032956(regulation of actin cytoskeleton organization);GO:0071944(cell periphery);GO:0005938(cell cortex);GO:0016579(protein deubiquitination);GO:0060071(Wnt signaling pathway, planar cell polarity pathway);GO:0032154(cleavage furrow);GO:0043296(apical junction complex);GO:0016032(viral process);GO:0043312(neutrophil degranulation);GO:0043123(positive regulation of I-kappaB kinase/NF-kappaB signaling);GO:0021762(substantia nigra development);GO:0030334(regulation of cell migration);GO:0042346(positive regulation of NF-kappaB import into nucleus);GO:0030667(secretory granule membrane);GO:0030168(platelet activation);GO:0048015(phosphatidylinositol-mediated signaling);GO:0016477(cell migration);GO:0048013(ephrin receptor signaling pathway);GO:0048010(vascular endothelial growth factor receptor signaling pathway);GO:0030054(cell junction);GO:0030036(actin cytoskeleton organization);GO:2000145(regulation of cell motility);GO:0032467(positive regulation of cytokinesis);GO:0007266(Rho protein signal transduction);GO:0090307(mitotic spindle assembly);GO:0101003(ficolin-1-rich granule membrane);GO:0031532(actin cytoskeleton reorganization);GO:0043931(ossification involved in bone maturation);GO:0017022(myosin binding);GO:0043297(apical junction assembly);GO:0050919(negative chemotaxis);GO:0043542(endothelial cell migration);GO:0007179(transforming growth factor beta receptor signaling pathway);GO:0050772(positive regulation of axonogenesis);GO:0038027(apolipoprotein A-I-mediated signaling pathway);GO:0060193(positive regulation of lipase activity);GO:0050771(negative regulation of axonogenesis);GO:0031982(vesicle);GO:0043149(stress fiber assembly);GO:2000406(positive regulation of T cell migration);GO:0051496(positive regulation of stress fiber assembly);GO:0043197(dendritic spine);GO:0033688(regulation of osteoblast proliferation);GO:0035385(Roundabout signaling pathway);GO:0036089(cleavage furrow formation);GO:0045666(positive regulation of neuron differentiation);GO:0045792(negative regulation of cell size);GO:0061383(trabecula morphogenesis);GO:0090051(negative regulation of cell migration involved in sprouting angiogenesis);GO:0097498(endothelial tube lumen extension);GO:1903673(mitotic cleavage furrow formation);GO:1990869(cellular response to chemokine);GO:0005768(endosome);GO:0005768(endosome)","04014(Ras signaling pathway);04015(Rap1 signaling pathway);04310(Wnt signaling pathway);04350(TGF-beta signaling pathway);04072(Phospholipase D signaling pathway);04071(Sphingolipid signaling pathway);04024(cAMP signaling pathway);04022(cGMP - PKG signaling pathway);04150(mTOR signaling pathway);04144(Endocytosis);04510(Focal adhesion);04520(Adherens junction);04530(Tight junction);04810(Regulation of actin cytoskeleton);04611(Platelet activation);04621(NOD-like receptor signaling pathway);04660(T cell receptor signaling pathway);04670(Leukocyte transendothelial migration);04062(Chemokine signaling pathway);04921(Oxytocin signaling pathway);04270(Vascular smooth muscle contraction);04972(Pancreatic secretion);04722(Neurotrophin signaling pathway);04360(Axon guidance);05200(Pathways in cancer);05206(MicroRNAs in cancer);05205(Proteoglycans in cancer);05203(Viral carcinogenesis);05210(Colorectal cancer);05418(Fluid shear stress and atherosclerosis);05130(Pathogenic Escherichia coli infection);05133(Pertussis);05152(Tuberculosis);05100(Bacterial invasion of epithelial cells);05100(Bacterial invasion of epithelial cells)","K04513","NA","ras homolog family member A [Source:HGNC Symbol;Acc:HGNC:667]",{"v":192.53865631371,"d":"192.54"},{"v":97.2907831642138,"d":"97.29"},{"v":1.97900201901685,"d":"1.98"},{"v":0.984773084252083,"d":"0.98"},{"v":0.276059836410108,"d":"0.28"},{"v":0.806815571258524,"d":"0.81"},"up","no"]
["ENSG00000196204","RNF216P1","ENST00000471244;ENST00000404006;ENST00000406608;ENST00000466622;ENST00000404404;ENST00000406089;ENST00000429902;ENST00000494947;ENST00000403969;ENST00000464479;ENST00000493407","NA","NA","NA","NA","ring finger protein 216 pseudogene 1 [Source:HGNC Symbol;Acc:HGNC:33610]",{"v":0.925659207259528,"d":"0.93"},{"v":1.26840953448276,"d":"1.27"},{"v":0.729779445908217,"d":"0.73"},{"v":-0.454467576609351,"d":"-0.45"},{"v":0.277766810237908,"d":"0.28"},{"v":0.808971293859696,"d":"0.81"},"down","no"]
["ENSG00000158477","CD1A","ENST00000289429","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0006955(immune response);GO:0045121(membrane raft);GO:0002376(immune system process);GO:0002250(adaptive immune response);GO:0050776(regulation of immune response);GO:0005887(integral component of plasma membrane);GO:0005768(endosome);GO:0010008(endosome membrane);GO:0030881(beta-2-microglobulin binding);GO:0030883(endogenous lipid antigen binding);GO:0030884(exogenous lipid antigen binding);GO:0071723(lipopeptide binding);GO:0048007(antigen processing and presentation, exogenous lipid antigen via MHC class Ib)","04530(Tight junction);04640(Hematopoietic cell lineage)","K06448","NA","CD1a molecule [Source:HGNC Symbol;Acc:HGNC:1634]",{"v":0.467343,"d":"0.47"},{"v":0.668275,"d":"0.67"},{"v":0.699327372713329,"d":"0.70"},{"v":-0.515960119364939,"d":"-0.52"},{"v":0.278899192554931,"d":"0.28"},{"v":0.810321822151716,"d":"0.81"},"down","no"]
["MSTRG.2551","EHBP1L1","ENST00000309295;ENST00000526990;ENST00000533237;ENST00000529099;ENST00000529056;ENST00000533364;ENST00000634639;ENST00000531106;ENST00000533465;ENST00000527214;ENST00000529596","GO:0016020(membrane);GO:0005768(endosome);GO:0003674(molecular_function);GO:0008150(biological_process);GO:0008150(biological_process)","NA","NA","NA","EH domain binding protein 1 like 1 [Source:HGNC Symbol;Acc:HGNC:30682]",{"v":14.0785203993473,"d":"14.08"},{"v":7.1287716396677,"d":"7.13"},{"v":1.97488727525063,"d":"1.97"},{"v":0.981770307933727,"d":"0.98"},{"v":0.279711240631426,"d":"0.28"},{"v":0.811260398964225,"d":"0.81"},"up","no"]
["MSTRG.6747","SYNRG","ENST00000616179;ENST00000621136;ENST00000612223;ENST00000618829;ENST00000619541;ENST00000614000;ENST00000612770;ENST00000611910;ENST00000620424;ENST00000622045;ENST00000619914;ENST00000614196;MSTRG.6747.11","GO:0006810(transport);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0015031(protein transport);GO:0005794(Golgi apparatus);GO:0005515(protein binding);GO:0006897(endocytosis);GO:0006886(intracellular protein transport);GO:0030121(AP-1 adaptor complex);GO:0030121(AP-1 adaptor complex)","NA","NA","NA","synergin gamma [Source:HGNC Symbol;Acc:HGNC:557]",{"v":6.51064981298592,"d":"6.51"},{"v":3.30364296743013,"d":"3.30"},{"v":1.97074861816878,"d":"1.97"},{"v":0.978743762961518,"d":"0.98"},{"v":0.281226378389839,"d":"0.28"},{"v":0.812300242604663,"d":"0.81"},"up","no"]
["ENSG00000147889","CDKN2A","ENST00000579755;ENST00000498628;ENST00000497750;ENST00000577854;ENST00000380151;ENST00000494262;ENST00000470819;ENST00000578845;ENST00000479692","GO:0008285(negative regulation of cell proliferation);GO:0001953(negative regulation of cell-matrix adhesion);GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0005515(protein binding);GO:0007049(cell cycle);GO:0005829(cytosol);GO:0045892(negative regulation of transcription, DNA-templated);GO:0019901(protein kinase binding);GO:0090399(replicative senescence);GO:0030308(negative regulation of cell growth);GO:0032088(negative regulation of NF-kappaB transcription factor activity);GO:0007050(cell cycle arrest);GO:0007265(Ras protein signal transduction);GO:0090398(cellular senescence);GO:0034393(positive regulation of smooth muscle cell apoptotic process);GO:0051059(NF-kappaB binding);GO:0000082(G1/S transition of mitotic cell cycle);GO:0035986(senescence-associated heterochromatin focus assembly);GO:2000774(positive regulation of cellular senescence);GO:0035985(senescence-associated heterochromatin focus);GO:0045736(negative regulation of cyclin-dependent protein serine/threonine kinase activity);GO:0004861(cyclin-dependent protein serine/threonine kinase inhibitor activity);GO:0042326(negative regulation of phosphorylation);GO:2000111(positive regulation of macrophage apoptotic process);GO:0006919(activation of cysteine-type endopeptidase activity involved in apoptotic process);GO:0005730(nucleolus);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0005739(mitochondrion);GO:0006915(apoptotic process);GO:0045893(positive regulation of transcription, DNA-templated);GO:0005654(nucleoplasm);GO:0016925(protein sumoylation);GO:0006364(rRNA processing);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0043065(positive regulation of apoptotic process);GO:0019789(SUMO transferase activity);GO:0070534(protein K63-linked ubiquitination);GO:0006469(negative regulation of protein kinase activity);GO:0031647(regulation of protein stability);GO:0008637(apoptotic mitochondrial changes);GO:0051444(negative regulation of ubiquitin-protein transferase activity);GO:0000209(protein polyubiquitination);GO:0008134(transcription factor binding);GO:1902510(regulation of apoptotic DNA fragmentation);GO:0097718(disordered domain specific binding);GO:0010628(positive regulation of gene expression);GO:0050821(protein stabilization);GO:1990000(amyloid fibril formation);GO:0033088(negative regulation of immature T cell proliferation in thymus);GO:1990948(ubiquitin ligase inhibitor activity);GO:1904667(negative regulation of ubiquitin protein ligase activity);GO:2000059(negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process);GO:2000435(negative regulation of protein neddylation);GO:0031648(protein destabilization);GO:0030889(negative regulation of B cell proliferation);GO:0055105(ubiquitin-protein transferase inhibitor activity);GO:0010389(regulation of G2/M transition of mitotic cell cycle);GO:0033235(positive regulation of protein sumoylation);GO:0048103(somatic stem cell division);GO:0048103(somatic stem cell division)","04110(Cell cycle);04115(p53 signaling pathway);04218(Cellular senescence);05200(Pathways in cancer);05206(MicroRNAs in cancer);05203(Viral carcinogenesis);05212(Pancreatic cancer);05225(Hepatocellular carcinoma);05214(Glioma);05220(Chronic myeloid leukemia);05218(Melanoma);05219(Bladder cancer);05223(Non-small cell lung cancer);05166(HTLV-I infection);01524(Platinum drug resistance);01522(Endocrine resistance);01522(Endocrine resistance)","K06621","NA","cyclin dependent kinase inhibitor 2A [Source:HGNC Symbol;Acc:HGNC:1787]",{"v":0.177198071610072,"d":"0.18"},{"v":0.250635992376992,"d":"0.25"},{"v":0.706993715984498,"d":"0.71"},{"v":-0.5002307029903,"d":"-0.50"},{"v":0.283111885299817,"d":"0.28"},{"v":0.813909327692553,"d":"0.81"},"down","no"]
["ENSG00000125482","TTF1","ENST00000334270;ENST00000461970;ENST00000612514","GO:0005634(nucleus);GO:0005730(nucleolus);GO:0005829(cytosol);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0005886(plasma membrane);GO:0003682(chromatin binding);GO:0006338(chromatin remodeling);GO:0006361(transcription initiation from RNA polymerase I promoter);GO:0006363(termination of RNA polymerase I transcription);GO:0005654(nucleoplasm);GO:0044267(cellular protein metabolic process);GO:0000981(RNA polymerase II transcription factor activity, sequence-specific DNA binding);GO:0030154(cell differentiation);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0043565(sequence-specific DNA binding);GO:0006353(DNA-templated transcription, termination);GO:0008156(negative regulation of DNA replication);GO:0044212(transcription regulatory region DNA binding);GO:0001135(transcription factor activity, RNA polymerase II transcription factor recruiting);GO:0001135(transcription factor activity, RNA polymerase II transcription factor recruiting)","04918(Thyroid hormone synthesis);04918(Thyroid hormone synthesis)","K15225","NA","transcription termination factor 1 [Source:HGNC Symbol;Acc:HGNC:12397]",{"v":3.8688129748056,"d":"3.87"},{"v":1.96239233219285,"d":"1.96"},{"v":1.97147782904474,"d":"1.97"},{"v":0.979277486196649,"d":"0.98"},{"v":0.28379904254309,"d":"0.28"},{"v":0.813909327692553,"d":"0.81"},"up","no"]
["MSTRG.10719","RAB5A","ENST00000273047;ENST00000476544;ENST00000446547;ENST00000473608;ENST00000443878;ENST00000412966;ENST00000469122;ENST00000422242","GO:0006810(transport);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0015031(protein transport);GO:0005525(GTP binding);GO:0000166(nucleotide binding);GO:0003924(GTPase activity);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0042995(cell projection);GO:0005515(protein binding);GO:0042470(melanosome);GO:0019001(guanyl nucleotide binding);GO:0006897(endocytosis);GO:0001726(ruffle);GO:0005768(endosome);GO:0005769(early endosome);GO:0015629(actin cytoskeleton);GO:0030139(endocytic vesicle);GO:0045121(membrane raft);GO:0045335(phagocytic vesicle);GO:0031410(cytoplasmic vesicle);GO:0070062(extracellular exosome);GO:0030670(phagocytic vesicle membrane);GO:0061024(membrane organization);GO:0010008(endosome membrane);GO:0043687(post-translational protein modification);GO:0031901(early endosome membrane);GO:0030100(regulation of endocytosis);GO:0019003(GDP binding);GO:0045921(positive regulation of exocytosis);GO:0006909(phagocytosis);GO:0006661(phosphatidylinositol biosynthetic process);GO:0036465(synaptic vesicle recycling);GO:0043195(terminal bouton);GO:0039694(viral RNA genome replication);GO:0007596(blood coagulation);GO:0030665(clathrin-coated vesicle membrane);GO:0043025(neuronal cell body);GO:0051489(regulation of filopodium assembly);GO:0030425(dendrite);GO:0008021(synaptic vesicle);GO:0030424(axon);GO:0036477(somatodendritic compartment);GO:2000300(regulation of synaptic vesicle exocytosis);GO:0045022(early endosome to late endosome transport);GO:0045056(transcytosis);GO:0051036(regulation of endosome size);GO:2000286(receptor internalization involved in canonical Wnt signaling pathway);GO:2000785(regulation of autophagosome assembly);GO:0043679(axon terminus);GO:0098559(cytoplasmic side of early endosome membrane);GO:0098559(cytoplasmic side of early endosome membrane)","04014(Ras signaling pathway);04144(Endocytosis);04145(Phagosome);04962(Vasopressin-regulated water reabsorption);05014(Amyotrophic lateral sclerosis (ALS));05152(Tuberculosis);05146(Amoebiasis);05146(Amoebiasis)","K07887","NA","RAB5A, member RAS oncogene family [Source:HGNC Symbol;Acc:HGNC:9783]",{"v":12.641017868428,"d":"12.64"},{"v":6.43488582457067,"d":"6.43"},{"v":1.96445099618708,"d":"1.96"},{"v":0.974126179789648,"d":"0.97"},{"v":0.284917119655737,"d":"0.28"},{"v":0.813953147359356,"d":"0.81"},"up","no"]
["ENSG00000134709","HOOK1","ENST00000371208;ENST00000465876;ENST00000491135;ENST00000474695;ENST00000466803","GO:0006810(transport);GO:0005737(cytoplasm);GO:0015031(protein transport);GO:0005829(cytosol);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0007275(multicellular organism development);GO:0030154(cell differentiation);GO:0005874(microtubule);GO:0007283(spermatogenesis);GO:0042802(identical protein binding);GO:0005813(centrosome);GO:0008333(endosome to lysosome transport);GO:0008017(microtubule binding);GO:0051959(dynein light intermediate chain binding);GO:0030705(cytoskeleton-dependent intracellular transport);GO:0031122(cytoplasmic microtubule organization);GO:0007040(lysosome organization);GO:0007032(endosome organization);GO:0045022(early endosome to late endosome transport);GO:0030897(HOPS complex);GO:0070695(FHF complex);GO:0003779(actin binding);GO:0007286(spermatid development);GO:0015630(microtubule cytoskeleton);GO:0015630(microtubule cytoskeleton)","NA","NA","NA","hook microtubule tethering protein 1 [Source:HGNC Symbol;Acc:HGNC:19884]",{"v":0.76422474652264,"d":"0.76"},{"v":0.385469493933116,"d":"0.39"},{"v":1.98258165315474,"d":"1.98"},{"v":0.987380284933322,"d":"0.99"},{"v":0.285398778366957,"d":"0.29"},{"v":0.814073521672636,"d":"0.81"},"up","no"]
["MSTRG.1010","AQP10","ENST00000324978;ENST00000355197;ENST00000484864","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005215(transporter activity);GO:0005886(plasma membrane);GO:0015250(water channel activity);GO:0015254(glycerol channel activity);GO:0006833(water transport);GO:0009636(response to toxic substance);GO:0015265(urea channel activity);GO:0071918(urea transmembrane transport);GO:0015793(glycerol transport);GO:0015793(glycerol transport)","NA","NA","NA","aquaporin 10 [Source:HGNC Symbol;Acc:HGNC:16029]",{"v":0.477366316753927,"d":"0.48"},{"v":0.668512882198953,"d":"0.67"},{"v":0.714071978962793,"d":"0.71"},{"v":-0.485858588617952,"d":"-0.49"},{"v":0.286807461926622,"d":"0.29"},{"v":0.815334258780603,"d":"0.82"},"down","no"]
["MSTRG.4642","GLRX5","ENST00000331334;ENST00000557731;ENST00000553672","GO:0046872(metal ion binding);GO:0005739(mitochondrion);GO:0045454(cell redox homeostasis);GO:0055114(oxidation-reduction process);GO:0005759(mitochondrial matrix);GO:0051536(iron-sulfur cluster binding);GO:0009249(protein lipoylation);GO:0009055(electron carrier activity);GO:0015035(protein disulfide oxidoreductase activity);GO:0051537(2 iron, 2 sulfur cluster binding);GO:0030097(hemopoiesis);GO:0044281(small molecule metabolic process);GO:0015036(disulfide oxidoreductase activity);GO:0005634(nucleus);GO:0030425(dendrite);GO:0043025(neuronal cell body);GO:0043025(neuronal cell body)","NA","NA","NA","glutaredoxin 5 [Source:HGNC Symbol;Acc:HGNC:20134]",{"v":12.6699363356766,"d":"12.67"},{"v":17.0608136393673,"d":"17.06"},{"v":0.742633769027352,"d":"0.74"},{"v":-0.429277176004137,"d":"-0.43"},{"v":0.288679296974556,"d":"0.29"},{"v":0.815681628543233,"d":"0.82"},"down","no"]
["ENSG00000067369","TP53BP1","ENST00000382044;ENST00000571145;ENST00000414758;ENST00000450115;ENST00000477089;ENST00000434595;ENST00000417342;ENST00000434561;ENST00000476454;ENST00000411772;ENST00000467474;ENST00000263801;ENST00000572085","GO:0051091(positive regulation of sequence-specific DNA binding transcription factor activity);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0005694(chromosome);GO:0005515(protein binding);GO:0006281(DNA repair);GO:0006974(cellular response to DNA damage stimulus);GO:0016604(nuclear body);GO:0045893(positive regulation of transcription, DNA-templated);GO:0000775(chromosome, centromeric region);GO:0000776(kinetochore);GO:0000777(condensed chromosome kinetochore);GO:0005737(cytoplasm);GO:0006303(double-strand break repair via nonhomologous end joining);GO:0001102(RNA polymerase II activating transcription factor binding);GO:0035064(methylated histone binding);GO:0000781(chromosome, telomeric region);GO:0016925(protein sumoylation);GO:0051260(protein homooligomerization);GO:0035861(site of double-strand break);GO:0002039(p53 binding);GO:2000042(negative regulation of double-strand break repair via homologous recombination);GO:0045830(positive regulation of isotype switching);GO:0001104(RNA polymerase II transcription cofactor activity);GO:0003684(damaged DNA binding);GO:0042162(telomeric DNA binding);GO:0043565(sequence-specific DNA binding);GO:0061649(ubiquitin modification-dependent histone binding);GO:0000077(DNA damage checkpoint);GO:0071481(cellular response to X-ray);GO:0000784(nuclear chromosome, telomeric region);GO:0005657(replication fork);GO:1990391(DNA repair complex);GO:1990391(DNA repair complex)","04621(NOD-like receptor signaling pathway);04621(NOD-like receptor signaling pathway)","K20915","NA","tumor protein p53 binding protein 1 [Source:HGNC Symbol;Acc:HGNC:11999]",{"v":1.81650206912478,"d":"1.82"},{"v":0.926313245785544,"d":"0.93"},{"v":1.96100193686028,"d":"1.96"},{"v":0.97159096046496,"d":"0.97"},{"v":0.289536424075012,"d":"0.29"},{"v":0.816985170200756,"d":"0.82"},"up","no"]
["MSTRG.13310","CITED2","ENST00000367651;ENST00000537332;ENST00000536159","GO:0043066(negative regulation of apoptotic process);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0060412(ventricular septum morphogenesis);GO:0003151(outflow tract morphogenesis);GO:0030336(negative regulation of cell migration);GO:0005634(nucleus);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0005515(protein binding);GO:0007275(multicellular organism development);GO:0030154(cell differentiation);GO:0003713(transcription coactivator activity);GO:0045893(positive regulation of transcription, DNA-templated);GO:0003714(transcription corepressor activity);GO:0005654(nucleoplasm);GO:0010628(positive regulation of gene expression);GO:0007507(heart development);GO:0003682(chromatin binding);GO:0008283(cell proliferation);GO:0001666(response to hypoxia);GO:0010629(negative regulation of gene expression);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0030511(positive regulation of transforming growth factor beta receptor signaling pathway);GO:0045892(negative regulation of transcription, DNA-templated);GO:0000790(nuclear chromatin);GO:0043234(protein complex);GO:0019904(protein domain specific binding);GO:0043627(response to estrogen);GO:0001106(RNA polymerase II transcription corepressor activity);GO:0022409(positive regulation of cell-cell adhesion);GO:0045787(positive regulation of cell cycle);GO:0007368(determination of left/right symmetry);GO:0007530(sex determination);GO:0001889(liver development);GO:1900164(nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry);GO:0035035(histone acetyltransferase binding);GO:0003156(regulation of animal organ formation);GO:0035802(adrenal cortex formation);GO:2000020(positive regulation of male gonad development);GO:0034405(response to fluid shear stress);GO:0048536(spleen development);GO:0050693(LBD domain binding);GO:0035360(positive regulation of peroxisome proliferator activated receptor signaling pathway);GO:0001105(RNA polymerase II transcription coactivator activity);GO:0070986(left/right axis specification);GO:0060971(embryonic heart tube left/right pattern formation);GO:0060972(left/right pattern formation);GO:0061428(negative regulation of transcription from RNA polymerase II promoter in response to hypoxia);GO:0001102(RNA polymerase II activating transcription factor binding);GO:0046332(SMAD binding);GO:0001568(blood vessel development);GO:0001570(vasculogenesis);GO:0001701(in utero embryonic development);GO:0001829(trophectodermal cell differentiation);GO:0001841(neural tube formation);GO:0001843(neural tube closure);GO:0001892(embryonic placenta development);GO:0001944(vasculature development);GO:0001947(heart looping);GO:0002089(lens morphogenesis in camera-type eye);GO:0002244(hematopoietic progenitor cell differentiation);GO:0002521(leukocyte differentiation);GO:0003197(endocardial cushion development);GO:0003281(ventricular septum development);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0007179(transforming growth factor beta receptor signaling pathway);GO:0007417(central nervous system development);GO:0007422(peripheral nervous system development);GO:0007569(cell aging);GO:0008584(male gonad development);GO:0009612(response to mechanical stimulus);GO:0021602(cranial nerve morphogenesis);GO:0030325(adrenal gland development);GO:0030851(granulocyte differentiation);GO:0035914(skeletal muscle cell differentiation);GO:0046697(decidualization);GO:0048538(thymus development);GO:0048596(embryonic camera-type eye morphogenesis);GO:0048821(erythrocyte development);GO:0060136(embryonic process involved in female pregnancy);GO:0060349(bone morphogenesis);GO:0060411(cardiac septum morphogenesis);GO:0061156(pulmonary artery morphogenesis);GO:0061308(cardiac neural crest cell development involved in heart development);GO:0061371(determination of heart left/right asymmetry);GO:0071363(cellular response to growth factor stimulus);GO:0071363(cellular response to growth factor stimulus)","04137(Mitophagy - animal);04137(Mitophagy - animal)","K21361","NA","Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2 [Source:HGNC Symbol;Acc:HGNC:1987]",{"v":11.9466575613412,"d":"11.95"},{"v":16.0496957554241,"d":"16.05"},{"v":0.744354144987686,"d":"0.74"},{"v":-0.425938912188465,"d":"-0.43"},{"v":0.291047743602993,"d":"0.29"},{"v":0.816985170200756,"d":"0.82"},"down","no"]
["MSTRG.7798","AC114271.1","ENST00000612689","NA","NA","NA","NA",null,{"v":4.619966,"d":"4.62"},{"v":6.216537,"d":"6.22"},{"v":0.74317357075169,"d":"0.74"},{"v":-0.428228898365201,"d":"-0.43"},{"v":0.291404105219834,"d":"0.29"},{"v":0.816985170200756,"d":"0.82"},"down","no"]
["MSTRG.5895","BCLAF1P2","ENST00000624956","NA","NA","NA","NA","BCL2 associated transcription factor 1 pseudogene 2 [Source:HGNC Symbol;Acc:HGNC:51807]",{"v":3.758696,"d":"3.76"},{"v":1.91355,"d":"1.91"},{"v":1.96425282851245,"d":"1.96"},{"v":0.973980637883484,"d":"0.97"},{"v":0.292590229932413,"d":"0.29"},{"v":0.816985170200756,"d":"0.82"},"up","no"]
["MSTRG.6332","MINK1","ENST00000453408;ENST00000355280;ENST00000571207;ENST00000574453;ENST00000572629;ENST00000576037;ENST00000575511;ENST00000574871;ENST00000572330;ENST00000572304;ENST00000577021;ENST00000571526","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0005794(Golgi apparatus);GO:0005886(plasma membrane);GO:0042995(cell projection);GO:0005515(protein binding);GO:0007275(multicellular organism development);GO:0030054(cell junction);GO:0045202(synapse);GO:0045211(postsynaptic membrane);GO:0000185(activation of MAPKKK activity);GO:0030425(dendrite);GO:0030424(axon);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0014069(postsynaptic density);GO:0007268(chemical synaptic transmission);GO:0030334(regulation of cell migration);GO:0048812(neuron projection morphogenesis);GO:0042981(regulation of apoptotic process);GO:0046777(protein autophosphorylation);GO:0008349(MAP kinase kinase kinase kinase activity);GO:0007346(regulation of mitotic cell cycle);GO:0035556(intracellular signal transduction);GO:0046330(positive regulation of JNK cascade);GO:0006950(response to stress);GO:0031532(actin cytoskeleton reorganization);GO:2000311(regulation of AMPA receptor activity);GO:0048813(dendrite morphogenesis);GO:0001952(regulation of cell-matrix adhesion);GO:0022407(regulation of cell-cell adhesion);GO:0007254(JNK cascade);GO:0007254(JNK cascade)","NA","NA","NA","misshapen like kinase 1 [Source:HGNC Symbol;Acc:HGNC:17565]",{"v":8.33693690776513,"d":"8.34"},{"v":4.27974803697071,"d":"4.28"},{"v":1.9479971334168,"d":"1.95"},{"v":0.961991554417993,"d":"0.96"},{"v":0.292800506189232,"d":"0.29"},{"v":0.816985170200756,"d":"0.82"},"up","no"]
["MSTRG.5538","NTHL1","ENST00000219066;ENST00000561841;ENST00000565406;ENST00000566380;ENST00000623977;ENST00000561862;ENST00000562120;ENST00000568513","GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0016787(hydrolase activity);GO:0003677(DNA binding);GO:0003824(catalytic activity);GO:0016829(lyase activity);GO:0005739(mitochondrion);GO:0006281(DNA repair);GO:0008152(metabolic process);GO:0016798(hydrolase activity, acting on glycosyl bonds);GO:0006974(cellular response to DNA damage stimulus);GO:0004519(endonuclease activity);GO:0003906(DNA-(apurinic or apyrimidinic site) lyase activity);GO:0006284(base-excision repair);GO:0051536(iron-sulfur cluster binding);GO:0051539(4 iron, 4 sulfur cluster binding);GO:0005515(protein binding);GO:0005654(nucleoplasm);GO:0003690(double-stranded DNA binding);GO:0019104(DNA N-glycosylase activity);GO:0000703(oxidized pyrimidine nucleobase lesion DNA N-glycosylase activity);GO:0006285(base-excision repair, AP site formation);GO:0006296(nucleotide-excision repair, DNA incision, 5'-to lesion);GO:0008534(oxidized purine nucleobase lesion DNA N-glycosylase activity);GO:0045008(depyrimidination);GO:0045008(depyrimidination)","03410(Base excision repair);03410(Base excision repair)","K10773","EC:4.2.99.18","nth like DNA glycosylase 1 [Source:HGNC Symbol;Acc:HGNC:8028]",{"v":0.929708216049383,"d":"0.93"},{"v":1.27223647613169,"d":"1.27"},{"v":0.730766829509727,"d":"0.73"},{"v":-0.452516945306065,"d":"-0.45"},{"v":0.295703067239404,"d":"0.30"},{"v":0.820453600538228,"d":"0.82"},"down","no"]
["ENSG00000217416","ISCA1P1","ENST00000426679","NA","NA","NA","NA","iron-sulfur cluster assembly 1 pseudogene 1 [Source:HGNC Symbol;Acc:HGNC:33263]",{"v":2.81384,"d":"2.81"},{"v":3.858507,"d":"3.86"},{"v":0.729256160478651,"d":"0.73"},{"v":-0.455502426373495,"d":"-0.46"},{"v":0.297111840639946,"d":"0.30"},{"v":0.821709884580065,"d":"0.82"},"down","no"]
["ENSG00000211973","IGHV1-69","ENST00000390633","GO:0016020(membrane);GO:0005886(plasma membrane);GO:0005576(extracellular region);GO:0006508(proteolysis);GO:0006955(immune response);GO:0002376(immune system process);GO:0003823(antigen binding);GO:0002250(adaptive immune response);GO:0004252(serine-type endopeptidase activity);GO:0006898(receptor-mediated endocytosis);GO:0006956(complement activation);GO:0006958(complement activation, classical pathway);GO:0030449(regulation of complement activation);GO:0038095(Fc-epsilon receptor signaling pathway);GO:0038096(Fc-gamma receptor signaling pathway involved in phagocytosis);GO:0050776(regulation of immune response);GO:0050900(leukocyte migration)","NA","NA","NA","immunoglobulin heavy variable 1-69 [Source:HGNC Symbol;Acc:HGNC:5558]",{"v":2.18159,"d":"2.18"},{"v":3.044807,"d":"3.04"},{"v":0.716495331231175,"d":"0.72"},{"v":-0.480970791141848,"d":"-0.48"},{"v":0.297990239072498,"d":"0.30"},{"v":0.82259930701438,"d":"0.82"},"down","no"]
["MSTRG.9309","STAT4","ENST00000392320;ENST00000463951;ENST00000413064;ENST00000409995;ENST00000470708;ENST00000358470;ENST00000495326;ENST00000450994;ENST00000495849","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0007165(signal transduction);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0004871(signal transducer activity);GO:0005515(protein binding);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0019221(cytokine-mediated signaling pathway);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0035722(interleukin-12-mediated signaling pathway);GO:0007259(JAK-STAT cascade);GO:0007259(JAK-STAT cascade)","04630(Jak-STAT signaling pathway);04217(Necroptosis);04658(Th1 and Th2 cell differentiation);05200(Pathways in cancer);05321(Inflammatiory bowel disease (IBD));05161(Hepatitis B);05161(Hepatitis B)","K11222","NA","signal transducer and activator of transcription 4 [Source:HGNC Symbol;Acc:HGNC:11365]",{"v":9.24626559952941,"d":"9.25"},{"v":12.3151449837647,"d":"12.32"},{"v":0.750804445397837,"d":"0.75"},{"v":-0.413490902717472,"d":"-0.41"},{"v":0.299939304003247,"d":"0.30"},{"v":0.823980797653187,"d":"0.82"},"down","no"]
["ENSG00000156966","B3GNT7","ENST00000287590","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016740(transferase activity);GO:0016757(transferase activity, transferring glycosyl groups);GO:0006486(protein glycosylation);GO:0005794(Golgi apparatus);GO:0000139(Golgi membrane);GO:0008378(galactosyltransferase activity);GO:0016266(O-glycan processing);GO:0018146(keratan sulfate biosynthetic process);GO:0008532(N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity);GO:0008499(UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity)","00533(Glycosaminoglycan biosynthesis - keratan sulfate)","K09664","EC:2.4.1.-","UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 7 [Source:HGNC Symbol;Acc:HGNC:18811]",{"v":0.554577680504467,"d":"0.55"},{"v":0.279959769837099,"d":"0.28"},{"v":1.98091919002205,"d":"1.98"},{"v":0.986170027863754,"d":"0.99"},{"v":0.300432687423902,"d":"0.30"},{"v":0.824025696517188,"d":"0.82"},"up","no"]
["MSTRG.9426","CTDSP1","MSTRG.9426.6;ENST00000273062;ENST00000443891;ENST00000428361;ENST00000492545;ENST00000494067;ENST00000488627;ENST00000473420;ENST00000496785;ENST00000464255;ENST00000491064;ENST00000452977;ENST00000497677;ENST00000431127;ENST00000498160;ENST00000482272","GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0005654(nucleoplasm);GO:0016787(hydrolase activity);GO:0016791(phosphatase activity);GO:0004721(phosphoprotein phosphatase activity);GO:0005515(protein binding);GO:0070062(extracellular exosome);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0006470(protein dephosphorylation);GO:0008420(CTD phosphatase activity);GO:0016311(dephosphorylation);GO:0001933(negative regulation of protein phosphorylation);GO:0045665(negative regulation of neuron differentiation);GO:0050768(negative regulation of neurogenesis);GO:2000134(negative regulation of G1/S transition of mitotic cell cycle);GO:2000134(negative regulation of G1/S transition of mitotic cell cycle)","NA","NA","NA","CTD small phosphatase 1 [Source:HGNC Symbol;Acc:HGNC:21614]",{"v":27.9216599373286,"d":"27.92"},{"v":14.4774906061496,"d":"14.48"},{"v":1.92862566427557,"d":"1.93"},{"v":0.947573151318341,"d":"0.95"},{"v":0.302420124332872,"d":"0.30"},{"v":0.826354095030034,"d":"0.83"},"up","no"]
["MSTRG.15275","WAS","MSTRG.15275.5;ENST00000376701;MSTRG.15275.3;MSTRG.15275.4;MSTRG.15275.1;ENST00000474174;ENST00000470107;ENST00000483750;ENST00000465982","GO:0003779(actin binding);GO:0007015(actin filament organization);GO:2000601(positive regulation of Arp2/3 complex-mediated actin nucleation);GO:0005622(intracellular);GO:0005737(cytoplasm);GO:0042802(identical protein binding);GO:0008154(actin polymerization or depolymerization);GO:0016197(endosomal transport);GO:0030041(actin filament polymerization);GO:0030048(actin filament-based movement);GO:0042110(T cell activation);GO:0005911(cell-cell junction);GO:0012506(vesicle membrane);GO:0050790(regulation of catalytic activity);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0038096(Fc-gamma receptor signaling pathway involved in phagocytosis);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0050852(T cell receptor signaling pathway);GO:0017124(SH3 domain binding);GO:0007596(blood coagulation);GO:0030695(GTPase regulator activity);GO:0006461(protein complex assembly);GO:0015629(actin cytoskeleton);GO:0006952(defense response);GO:0019901(protein kinase binding);GO:0008544(epidermis development);GO:0043274(phospholipase binding);GO:0006955(immune response);GO:0051497(negative regulation of stress fiber assembly);GO:0031267(small GTPase binding);GO:0048365(Rac GTPase binding);GO:0002625(regulation of T cell antigen processing and presentation);GO:0008064(regulation of actin polymerization or depolymerization);GO:0010591(regulation of lamellipodium assembly);GO:0032488(Cdc42 protein signal transduction);GO:0051492(regulation of stress fiber assembly);GO:2000146(negative regulation of cell motility);GO:0005884(actin filament);GO:0005884(actin filament)","04144(Endocytosis);04520(Adherens junction);04530(Tight junction);04810(Regulation of actin cytoskeleton);04666(Fc gamma R-mediated phagocytosis);04062(Chemokine signaling pathway);05231(Choline metabolism in cancer);05130(Pathogenic Escherichia coli infection);05132(Salmonella infection);05131(Shigellosis);05100(Bacterial invasion of epithelial cells);05100(Bacterial invasion of epithelial cells)","K05747","NA","Wiskott-Aldrich syndrome [Source:HGNC Symbol;Acc:HGNC:12731]",{"v":46.084534473467,"d":"46.08"},{"v":23.9230283832547,"d":"23.92"},{"v":1.92636708593819,"d":"1.93"},{"v":0.9458826474182,"d":"0.95"},{"v":0.303219728392812,"d":"0.30"},{"v":0.82678503656518,"d":"0.83"},"up","no"]
["MSTRG.8823","DUSP11","ENST00000272444;ENST00000443070;ENST00000477458;ENST00000480948","GO:0003723(RNA binding);GO:0005634(nucleus);GO:0016607(nuclear speck);GO:0016787(hydrolase activity);GO:0001650(fibrillar center);GO:0004725(protein tyrosine phosphatase activity);GO:0008138(protein tyrosine/serine/threonine phosphatase activity);GO:0016791(phosphatase activity);GO:0006470(protein dephosphorylation);GO:0016311(dephosphorylation);GO:0035335(peptidyl-tyrosine dephosphorylation);GO:0045171(intercellular bridge);GO:0098519(nucleotide phosphatase activity, acting on free nucleotides);GO:0006396(RNA processing);GO:0016070(RNA metabolic process);GO:0004651(polynucleotide 5'-phosphatase activity);GO:0098507(polynucleotide 5' dephosphorylation);GO:0098507(polynucleotide 5' dephosphorylation)","NA","NA","NA","dual specificity phosphatase 11 [Source:HGNC Symbol;Acc:HGNC:3066]",{"v":5.58268426467269,"d":"5.58"},{"v":7.4062623022009,"d":"7.41"},{"v":0.753778901810391,"d":"0.75"},{"v":-0.407786680197508,"d":"-0.41"},{"v":0.305502225328182,"d":"0.31"},{"v":0.828355952020973,"d":"0.83"},"down","no"]
["MSTRG.12246","EPB41L4A-AS1","ENST00000413221;ENST00000508590;ENST00000427306","NA","NA","NA","NA","EPB41L4A antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:30749]",{"v":1.92723855203349,"d":"1.93"},{"v":2.57084140251196,"d":"2.57"},{"v":0.749652837452513,"d":"0.75"},{"v":-0.415705453464079,"d":"-0.42"},{"v":0.306327816681501,"d":"0.31"},{"v":0.828355952020973,"d":"0.83"},"down","no"]
["MSTRG.12068","GAPT","ENST00000396776;ENST00000502276;ENST00000515443;ENST00000511178;ENST00000318469;ENST00000513924;ENST00000511930","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0001782(B cell homeostasis);GO:0002322(B cell proliferation involved in immune response);GO:0002381(immunoglobulin production involved in immunoglobulin mediated immune response);GO:0005886(plasma membrane);GO:0042113(B cell activation);GO:0042113(B cell activation)","NA","NA","NA","GRB2 binding adaptor protein, transmembrane [Source:HGNC Symbol;Acc:HGNC:26588]",{"v":3.019243604033,"d":"3.02"},{"v":4.0120915410938,"d":"4.01"},{"v":0.752536070802083,"d":"0.75"},{"v":-0.410167359632848,"d":"-0.41"},{"v":0.306845072471749,"d":"0.31"},{"v":0.828355952020973,"d":"0.83"},"down","no"]
["MSTRG.12979","FKBP5","ENST00000357266;ENST00000542713;ENST00000536438;ENST00000539068","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0016853(isomerase activity);GO:0005654(nucleoplasm);GO:0003755(peptidyl-prolyl cis-trans isomerase activity);GO:0000413(protein peptidyl-prolyl isomerization);GO:0005515(protein binding);GO:0005528(FK506 binding);GO:0031072(heat shock protein binding);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0061077(chaperone-mediated protein folding);GO:0006457(protein folding);GO:0006457(protein folding)","04915(Estrogen signaling pathway);04915(Estrogen signaling pathway)","K09571","EC:5.2.1.8","FK506 binding protein 5 [Source:HGNC Symbol;Acc:HGNC:3721]",{"v":6.10194441014302,"d":"6.10"},{"v":3.17917755494919,"d":"3.18"},{"v":1.91934684511213,"d":"1.92"},{"v":0.940615444471081,"d":"0.94"},{"v":0.308032138424867,"d":"0.31"},{"v":0.828355952020973,"d":"0.83"},"up","no"]
["ENSG00000167965","MLST8","ENST00000568194;ENST00000569417;ENST00000397124;ENST00000564679;ENST00000565687;ENST00000564088;ENST00000563067;ENST00000566835;ENST00000562239;ENST00000562392;ENST00000565269;ENST00000570224;ENST00000564294;ENST00000562844;ENST00000561651;ENST00000565330;ENST00000565717;ENST00000569848;ENST00000568542;ENST00000567282;ENST00000565250;ENST00000566653;ENST00000562352;ENST00000567928;ENST00000382450;ENST00000563107","GO:0005737(cytoplasm);GO:0005515(protein binding);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0032956(regulation of actin cytoskeleton organization);GO:0071902(positive regulation of protein serine/threonine kinase activity);GO:0038111(interleukin-7-mediated signaling pathway);GO:0048015(phosphatidylinositol-mediated signaling);GO:0032008(positive regulation of TOR signaling);GO:1900034(regulation of cellular response to heat);GO:0031295(T cell costimulation);GO:0031931(TORC1 complex);GO:0031932(TORC2 complex);GO:0007050(cell cycle arrest);GO:0016241(regulation of macroautophagy);GO:0038202(TORC1 signaling);GO:0043539(protein serine/threonine kinase activator activity);GO:0030838(positive regulation of actin filament polymerization);GO:0043087(regulation of GTPase activity);GO:0050731(positive regulation of peptidyl-tyrosine phosphorylation);GO:0050731(positive regulation of peptidyl-tyrosine phosphorylation)","04151(PI3K-Akt signaling pathway);04150(mTOR signaling pathway);04140(Autophagy - animal);04136(Autophagy - other eukaryotes);04136(Autophagy - other eukaryotes)","K08266","NA","MTOR associated protein, LST8 homolog [Source:HGNC Symbol;Acc:HGNC:24825]",{"v":2.35253025792274,"d":"2.35"},{"v":3.12095630372427,"d":"3.12"},{"v":0.753785067453665,"d":"0.75"},{"v":-0.407774879513548,"d":"-0.41"},{"v":0.309171314109188,"d":"0.31"},{"v":0.829768077363069,"d":"0.83"},"down","no"]
["ENSG00000132323","ILKAP","ENST00000254654;ENST00000457149;ENST00000490837;ENST00000466468;ENST00000467133;ENST00000498727;ENST00000479400;ENST00000622223;ENST00000450411;ENST00000612675;ENST00000463129;ENST00000465131","GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0016787(hydrolase activity);GO:0003824(catalytic activity);GO:0006470(protein dephosphorylation);GO:0004721(phosphoprotein phosphatase activity);GO:0005515(protein binding);GO:0004722(protein serine/threonine phosphatase activity);GO:0043169(cation binding);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0007229(integrin-mediated signaling pathway);GO:0007229(integrin-mediated signaling pathway)","NA","NA","NA","ILK associated serine/threonine phosphatase [Source:HGNC Symbol;Acc:HGNC:15566]",{"v":2.02147792454412,"d":"2.02"},{"v":2.67433816285894,"d":"2.67"},{"v":0.755879698617884,"d":"0.76"},{"v":-0.403771453057301,"d":"-0.40"},{"v":0.311129427703018,"d":"0.31"},{"v":0.831852671296319,"d":"0.83"},"down","no"]
["MSTRG.12104","AC145138.1","ENST00000512908","NA","NA","NA","NA",null,{"v":5.61095,"d":"5.61"},{"v":2.926985,"d":"2.93"},{"v":1.91697258441707,"d":"1.92"},{"v":0.938829704450841,"d":"0.94"},{"v":0.31170630227524,"d":"0.31"},{"v":0.831852671296319,"d":"0.83"},"up","no"]
["MSTRG.15271","RBM3","ENST00000376755;ENST00000354480;ENST00000466764;ENST00000376759;ENST00000485213;ENST00000490127;ENST00000489344;ENST00000491236;ENST00000488216;ENST00000491240","GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005730(nucleolus);GO:0005654(nucleoplasm);GO:0042995(cell projection);GO:0005515(protein binding);GO:0045727(positive regulation of translation);GO:0030425(dendrite);GO:0006417(regulation of translation);GO:0006396(RNA processing);GO:0015934(large ribosomal subunit);GO:0015934(large ribosomal subunit)","NA","NA","NA","RNA binding motif (RNP1, RRM) protein 3 [Source:HGNC Symbol;Acc:HGNC:9900]",{"v":23.4403733851514,"d":"23.44"},{"v":30.7851757555615,"d":"30.79"},{"v":0.761417559258754,"d":"0.76"},{"v":-0.393240254218312,"d":"-0.39"},{"v":0.312987851338921,"d":"0.31"},{"v":0.831852671296319,"d":"0.83"},"down","no"]
["ENSG00000151729","SLC25A4","ENST00000281456;ENST00000491736","GO:0006810(transport);GO:0005634(nucleus);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005215(transporter activity);GO:0055085(transmembrane transport);GO:0005739(mitochondrion);GO:0005743(mitochondrial inner membrane);GO:0005515(protein binding);GO:0008637(apoptotic mitochondrial changes);GO:0043209(myelin sheath);GO:0016032(viral process);GO:0005887(integral component of plasma membrane);GO:0050796(regulation of insulin secretion);GO:0006091(generation of precursor metabolites and energy);GO:0005471(ATP:ADP antiporter activity);GO:0015207(adenine transmembrane transporter activity);GO:0015853(adenine transport);GO:0015867(ATP transport);GO:0000002(mitochondrial genome maintenance);GO:0015866(ADP transport);GO:0046902(regulation of mitochondrial membrane permeability);GO:0060546(negative regulation of necroptotic process);GO:0060546(negative regulation of necroptotic process)","04020(Calcium signaling pathway);04022(cGMP - PKG signaling pathway);04217(Necroptosis);04218(Cellular senescence);05012(Parkinson's disease);05016(Huntington's disease);05166(HTLV-I infection);05166(HTLV-I infection)","K05863","NA","solute carrier family 25 member 4 [Source:HGNC Symbol;Acc:HGNC:10990]",{"v":0.838306689925681,"d":"0.84"},{"v":1.10943321758877,"d":"1.11"},{"v":0.755617081438798,"d":"0.76"},{"v":-0.404272779306527,"d":"-0.40"},{"v":0.31365768104268,"d":"0.31"},{"v":0.831852671296319,"d":"0.83"},"down","no"]
["ENSG00000105778","AVL9","ENST00000318709;ENST00000470500;ENST00000459629;ENST00000409301;ENST00000446718;ENST00000467779","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005768(endosome);GO:0055037(recycling endosome);GO:0016477(cell migration);GO:0016477(cell migration)","NA","NA","NA","AVL9 cell migration associated [Source:HGNC Symbol;Acc:HGNC:28994]",{"v":2.48789131273294,"d":"2.49"},{"v":1.30371003645727,"d":"1.30"},{"v":1.90831645316898,"d":"1.91"},{"v":0.9323004310716,"d":"0.93"},{"v":0.315175112832997,"d":"0.32"},{"v":0.832734877616322,"d":"0.83"},"up","no"]
["MSTRG.15103","SNHG7","ENST00000416970;ENST00000414282;ENST00000447221;ENST00000436596","NA","NA","NA","NA","small nucleolar RNA host gene 7 [Source:HGNC Symbol;Acc:HGNC:28254]",{"v":1.36163414499425,"d":"1.36"},{"v":1.79466596962025,"d":"1.79"},{"v":0.758711742487863,"d":"0.76"},{"v":-0.398376228579433,"d":"-0.40"},{"v":0.316371882989282,"d":"0.32"},{"v":0.832734877616322,"d":"0.83"},"down","no"]
["MSTRG.4356","GMPR2","ENST00000355299;ENST00000399440;ENST00000420554;ENST00000559836;ENST00000557854;ENST00000559943;ENST00000561038;ENST00000558932;ENST00000561035;ENST00000558865;ENST00000559102;ENST00000559606;ENST00000559910;ENST00000559287;ENST00000560139;ENST00000456667;ENST00000558788;ENST00000559104;ENST00000348719;ENST00000558483;ENST00000558760;ENST00000559801;ENST00000558748;ENST00000560517;ENST00000558279;ENST00000620807;ENST00000559479;ENST00000561130;ENST00000558007","GO:0046872(metal ion binding);GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0003824(catalytic activity);GO:0003920(GMP reductase activity);GO:0006144(purine nucleobase metabolic process);GO:0009117(nucleotide metabolic process);GO:1902560(GMP reductase complex);GO:0005829(cytosol);GO:0043101(purine-containing compound salvage);GO:0046037(GMP metabolic process);GO:0006163(purine nucleotide metabolic process);GO:0006164(purine nucleotide biosynthetic process);GO:0003938(IMP dehydrogenase activity);GO:0003938(IMP dehydrogenase activity)","00230(Purine metabolism);00230(Purine metabolism)","K00364","EC:1.7.1.7","guanosine monophosphate reductase 2 [Source:HGNC Symbol;Acc:HGNC:4377]",{"v":8.47005833214286,"d":"8.47"},{"v":11.1005410010989,"d":"11.10"},{"v":0.763031128960684,"d":"0.76"},{"v":-0.390186179792014,"d":"-0.39"},{"v":0.316673375531355,"d":"0.32"},{"v":0.832734877616322,"d":"0.83"},"down","no"]
["MSTRG.15487","ABCD1","ENST00000218104;ENST00000443684;ENST00000370129","GO:0006810(transport);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0055085(transmembrane transport);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0042803(protein homodimerization activity);GO:0005515(protein binding);GO:0048471(perinuclear region of cytoplasm);GO:0042626(ATPase activity, coupled to transmembrane movement of substances);GO:0016887(ATPase activity);GO:0005777(peroxisome);GO:0005778(peroxisomal membrane);GO:0042802(identical protein binding);GO:0006635(fatty acid beta-oxidation);GO:0005829(cytosol);GO:0019899(enzyme binding);GO:0007031(peroxisome organization);GO:0005779(integral component of peroxisomal membrane);GO:0033540(fatty acid beta-oxidation using acyl-CoA oxidase);GO:0036109(alpha-linolenic acid metabolic process);GO:0005215(transporter activity);GO:0043651(linoleic acid metabolic process);GO:0005324(long-chain fatty acid transporter activity);GO:0015910(peroxisomal long-chain fatty acid import);GO:0042760(very long-chain fatty acid catabolic process);GO:0005325(peroxisomal fatty-acyl-CoA transporter activity);GO:0015919(peroxisomal membrane transport);GO:0042758(long-chain fatty acid catabolic process);GO:0005739(mitochondrion);GO:0005739(mitochondrion)","02010(ABC transporters);04146(Peroxisome);04146(Peroxisome)","K05675","NA","ATP binding cassette subfamily D member 1 [Source:HGNC Symbol;Acc:HGNC:61]",{"v":2.38912621781243,"d":"2.39"},{"v":1.24874177746279,"d":"1.25"},{"v":1.913226786299,"d":"1.91"},{"v":0.936007895156385,"d":"0.94"},{"v":0.318530475276059,"d":"0.32"},{"v":0.83331705550369,"d":"0.83"},"up","no"]
["MSTRG.8592","BABAM2;MRPL33","ENST00000344773;ENST00000296102;ENST00000379624;ENST00000448427;ENST00000379666;ENST00000436924;ENST00000342045;ENST00000379632;ENST00000379629;ENST00000496951;ENST00000483992;ENST00000476552;ENST00000361704;ENST00000604932;ENST00000472192","GO:0005829(cytosol);GO:0070531(BRCA1-A complex);GO:0070552(BRISC complex);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016569(covalent chromatin modification);GO:0051301(cell division);GO:0005515(protein binding);GO:0006281(DNA repair);GO:0006974(cellular response to DNA damage stimulus);GO:0007049(cell cycle);GO:0006915(apoptotic process);GO:0005654(nucleoplasm);GO:0016579(protein deubiquitination);GO:0070536(protein K63-linked deubiquitination);GO:0043066(negative regulation of apoptotic process);GO:0007165(signal transduction);GO:0031572(G2 DNA damage checkpoint);GO:0005164(tumor necrosis factor receptor binding);GO:0045739(positive regulation of DNA repair);GO:0006302(double-strand break repair);GO:0006303(double-strand break repair via nonhomologous end joining);GO:0010212(response to ionizing radiation);GO:0031593(polyubiquitin binding);GO:0000152(nuclear ubiquitin ligase complex);GO:0000268(peroxisome targeting sequence binding);GO:0030529(intracellular ribonucleoprotein complex);GO:0005622(intracellular);GO:0003735(structural constituent of ribosome);GO:0006412(translation);GO:0005840(ribosome);GO:0005739(mitochondrion);GO:0005743(mitochondrial inner membrane);GO:0070125(mitochondrial translational elongation);GO:0070126(mitochondrial translational termination);GO:0005762(mitochondrial large ribosomal subunit);GO:0005762(mitochondrial large ribosomal subunit)","03440(Homologous recombination);03010(Ribosome);03010(Ribosome)","K12173;K02913","NA","BRISC and BRCA1 A complex member 2 [Source:HGNC Symbol;Acc:HGNC:1106];mitochondrial ribosomal protein L33 [Source:HGNC Symbol;Acc:HGNC:14487]",{"v":3.95391864336879,"d":"3.95"},{"v":5.17859711395702,"d":"5.18"},{"v":0.763511537267969,"d":"0.76"},{"v":-0.389278137428398,"d":"-0.39"},{"v":0.319883825057643,"d":"0.32"},{"v":0.834020732390912,"d":"0.83"},"down","no"]
["MSTRG.4052","UBAC2","ENST00000460562;ENST00000403766;ENST00000468067;ENST00000494576;ENST00000480738;ENST00000473091;ENST00000474510;ENST00000355700;ENST00000457666;ENST00000376440","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005515(protein binding);GO:0004252(serine-type endopeptidase activity);GO:0006508(proteolysis);GO:0043130(ubiquitin binding);GO:1904153(negative regulation of retrograde protein transport, ER to cytosol);GO:0070972(protein localization to endoplasmic reticulum);GO:0070972(protein localization to endoplasmic reticulum)","NA","NA","NA","UBA domain containing 2 [Source:HGNC Symbol;Acc:HGNC:20486]",{"v":5.52440868998479,"d":"5.52"},{"v":7.21839243667174,"d":"7.22"},{"v":0.765323960764315,"d":"0.77"},{"v":-0.385857526619106,"d":"-0.39"},{"v":0.320405947563305,"d":"0.32"},{"v":0.834020732390912,"d":"0.83"},"down","no"]
["ENSG00000139832","RAB20","ENST00000267328","GO:0006810(transport);GO:0016020(membrane);GO:0015031(protein transport);GO:0005794(Golgi apparatus);GO:0043231(intracellular membrane-bounded organelle);GO:0005525(GTP binding);GO:0000166(nucleotide binding);GO:0003924(GTPase activity);GO:0031410(cytoplasmic vesicle);GO:0005886(plasma membrane);GO:0030670(phagocytic vesicle membrane);GO:0030100(regulation of endocytosis);GO:0005769(early endosome);GO:0090385(phagosome-lysosome fusion);GO:0045335(phagocytic vesicle);GO:0090383(phagosome acidification)","NA","NA","NA","RAB20, member RAS oncogene family [Source:HGNC Symbol;Acc:HGNC:18260]",{"v":3.552977,"d":"3.55"},{"v":4.662052,"d":"4.66"},{"v":0.762105828077422,"d":"0.76"},{"v":-0.391936746720763,"d":"-0.39"},{"v":0.321712600338484,"d":"0.32"},{"v":0.834020732390912,"d":"0.83"},"down","no"]
["ENSG00000125843","AP5S1","ENST00000615891;ENST00000379567;ENST00000379573;ENST00000246041;ENST00000455742","GO:0000724(double-strand break repair via homologous recombination);GO:0016197(endosomal transport);GO:0030119(AP-type membrane coat adaptor complex);GO:0006810(transport);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0015031(protein transport);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0005765(lysosomal membrane);GO:0005886(plasma membrane);GO:0006281(DNA repair);GO:0006974(cellular response to DNA damage stimulus);GO:0005764(lysosome);GO:0005515(protein binding);GO:0005768(endosome);GO:0031902(late endosome membrane);GO:0005770(late endosome);GO:0005770(late endosome)","NA","NA","NA","adaptor related protein complex 5 sigma 1 subunit [Source:HGNC Symbol;Acc:HGNC:15875]",{"v":0.536214079052823,"d":"0.54"},{"v":0.704890460655738,"d":"0.70"},{"v":0.760705540764447,"d":"0.76"},{"v":-0.394589981616402,"d":"-0.39"},{"v":0.321959437122919,"d":"0.32"},{"v":0.834020732390912,"d":"0.83"},"down","no"]
["MSTRG.5794","C16orf54","ENST00000329410","GO:0016020(membrane);GO:0016021(integral component of membrane)","NA","NA","NA","chromosome 16 open reading frame 54 [Source:HGNC Symbol;Acc:HGNC:26649]",{"v":71.139313,"d":"71.14"},{"v":37.672523,"d":"37.67"},{"v":1.88836072911814,"d":"1.89"},{"v":0.917134385673894,"d":"0.92"},{"v":0.323842518295514,"d":"0.32"},{"v":0.835056245111078,"d":"0.84"},"up","no"]
["MSTRG.2819","CASP4","ENST00000393150;ENST00000529565;ENST00000533730;ENST00000534356;ENST00000531333;ENST00000524843;ENST00000530309;ENST00000525116;ENST00000529183;ENST00000531546;ENST00000417440;ENST00000444739","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005829(cytosol);GO:0016787(hydrolase activity);GO:0042981(regulation of apoptotic process);GO:0005886(plasma membrane);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005739(mitochondrion);GO:0008233(peptidase activity);GO:0008234(cysteine-type peptidase activity);GO:0006508(proteolysis);GO:0005576(extracellular region);GO:0004197(cysteine-type endopeptidase activity);GO:0002376(immune system process);GO:0045087(innate immune response);GO:0006954(inflammatory response);GO:0050700(CARD domain binding);GO:0043234(protein complex);GO:0006915(apoptotic process);GO:0012501(programmed cell death);GO:0070059(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress);GO:0050727(regulation of inflammatory response);GO:1903265(positive regulation of tumor necrosis factor-mediated signaling pathway);GO:0097153(cysteine-type endopeptidase activity involved in apoptotic process);GO:0072557(IPAF inflammasome complex);GO:0097193(intrinsic apoptotic signaling pathway);GO:1904646(cellular response to amyloid-beta);GO:0061702(inflammasome complex);GO:0072559(NLRP3 inflammasome complex);GO:0097169(AIM2 inflammasome complex);GO:0097169(AIM2 inflammasome complex)","04621(NOD-like receptor signaling pathway);04621(NOD-like receptor signaling pathway)","K04394","EC:3.4.22.57;EC:3.4.22.64","caspase 4 [Source:HGNC Symbol;Acc:HGNC:1505]",{"v":23.9255914683021,"d":"23.93"},{"v":31.0408410136439,"d":"31.04"},{"v":0.770777810362344,"d":"0.77"},{"v":-0.375613055870495,"d":"-0.38"},{"v":0.325711568782902,"d":"0.33"},{"v":0.837018908669139,"d":"0.84"},"down","no"]
["MSTRG.10077","C21orf33","ENST00000291577;ENST00000493883;ENST00000348499;ENST00000427803;ENST00000449622;ENST00000470545;ENST00000480786;ENST00000495007;ENST00000488392","GO:0005739(mitochondrion);GO:0005739(mitochondrion)","NA","NA","NA","chromosome 21 open reading frame 33 [Source:HGNC Symbol;Acc:HGNC:1273]",{"v":3.36780307368082,"d":"3.37"},{"v":4.38247976930502,"d":"4.38"},{"v":0.768469736533408,"d":"0.77"},{"v":-0.37993964930167,"d":"-0.38"},{"v":0.326231184784987,"d":"0.33"},{"v":0.837480641680029,"d":"0.84"},"down","no"]
["ENSG00000171566","PLRG1","ENST00000499023;ENST00000503251;ENST00000512773;ENST00000506192;ENST00000509975;ENST00000512719;ENST00000506918;ENST00000506627;ENST00000515520;ENST00000504341;ENST00000302078;ENST00000503751","GO:0006397(mRNA processing);GO:0008380(RNA splicing);GO:0005634(nucleus);GO:0016607(nuclear speck);GO:0031965(nuclear membrane);GO:0001650(fibrillar center);GO:0005515(protein binding);GO:0005681(spliceosomal complex);GO:0005654(nucleoplasm);GO:0000398(mRNA splicing, via spliceosome);GO:0071013(catalytic step 2 spliceosome);GO:0071011(precatalytic spliceosome);GO:0005662(DNA replication factor A complex);GO:0034504(protein localization to nucleus);GO:1900087(positive regulation of G1/S transition of mitotic cell cycle);GO:0000974(Prp19 complex);GO:0080008(Cul4-RING E3 ubiquitin ligase complex);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016021(integral component of membrane)","03040(Spliceosome);03040(Spliceosome)","K12862","NA","pleiotropic regulator 1 [Source:HGNC Symbol;Acc:HGNC:9089]",{"v":3.49070587264805,"d":"3.49"},{"v":4.53573509704892,"d":"4.54"},{"v":0.769600913183665,"d":"0.77"},{"v":-0.377817583922906,"d":"-0.38"},{"v":0.327126731624066,"d":"0.33"},{"v":0.837563424033465,"d":"0.84"},"down","no"]
["MSTRG.7963","BST2","ENST00000252593;ENST00000533098;ENST00000527220","GO:0003723(RNA binding);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005794(Golgi apparatus);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0010951(negative regulation of endopeptidase activity);GO:0042803(protein homodimerization activity);GO:0005515(protein binding);GO:0004871(signal transducer activity);GO:0031225(anchored component of membrane);GO:0009615(response to virus);GO:0034341(response to interferon-gamma);GO:0035455(response to interferon-alpha);GO:0035456(response to interferon-beta);GO:0045071(negative regulation of viral genome replication);GO:0045087(innate immune response);GO:0051607(defense response to virus);GO:1901253(negative regulation of intracellular transport of viral material);GO:0009986(cell surface);GO:0045121(membrane raft);GO:0002376(immune system process);GO:0005768(endosome);GO:0070062(extracellular exosome);GO:0032956(regulation of actin cytoskeleton organization);GO:0005770(late endosome);GO:0005887(integral component of plasma membrane);GO:0043312(neutrophil degranulation);GO:0043123(positive regulation of I-kappaB kinase/NF-kappaB signaling);GO:0042113(B cell activation);GO:0016324(apical plasma membrane);GO:0007267(cell-cell signaling);GO:0007275(multicellular organism development);GO:0030308(negative regulation of cell growth);GO:0035577(azurophil granule membrane);GO:0008283(cell proliferation);GO:0060337(type I interferon signaling pathway);GO:0030336(negative regulation of cell migration);GO:0006959(humoral immune response);GO:0008191(metalloendopeptidase inhibitor activity);GO:0002737(negative regulation of plasmacytoid dendritic cell cytokine production);GO:0005771(multivesicular body);GO:0005771(multivesicular body)","NA","NA","NA","bone marrow stromal cell antigen 2 [Source:HGNC Symbol;Acc:HGNC:1119]",{"v":28.3088201796247,"d":"28.31"},{"v":36.6520950116175,"d":"36.65"},{"v":0.772365677068439,"d":"0.77"},{"v":-0.37264404067568,"d":"-0.37"},{"v":0.329114240299593,"d":"0.33"},{"v":0.839877327450367,"d":"0.84"},"down","no"]
["ENSG00000072310","SREBF1","ENST00000261646;ENST00000423161;ENST00000470247;ENST00000581707;ENST00000478616;ENST00000487401;ENST00000577897;ENST00000578469;ENST00000395751;ENST00000395756;ENST00000476994;ENST00000584760;ENST00000447641;ENST00000580540;ENST00000355815;ENST00000395757;ENST00000485080;ENST00000583080;ENST00000469356;ENST00000471445","GO:0046983(protein dimerization activity);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0005794(Golgi apparatus);GO:0006629(lipid metabolic process);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0008202(steroid metabolic process);GO:0030522(intracellular receptor signaling pathway);GO:0000139(Golgi membrane);GO:0031410(cytoplasmic vesicle);GO:0008203(cholesterol metabolic process);GO:0005515(protein binding);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:1903146(regulation of mitophagy);GO:1903214(regulation of protein targeting to mitochondrion);GO:0005635(nuclear envelope);GO:0007623(circadian rhythm);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0045540(regulation of cholesterol biosynthetic process);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0000977(RNA polymerase II regulatory region sequence-specific DNA binding);GO:0031647(regulation of protein stability);GO:0012507(ER to Golgi transport vesicle membrane);GO:0010867(positive regulation of triglyceride biosynthetic process);GO:0008610(lipid biosynthetic process);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:0000982(transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0001077(transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0003682(chromatin binding);GO:0004879(RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding);GO:0019901(protein kinase binding);GO:0032403(protein complex binding);GO:0032810(sterol response element binding);GO:0043565(sequence-specific DNA binding);GO:0044212(transcription regulatory region DNA binding);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0003062(regulation of heart rate by chemical signal);GO:0007568(aging);GO:0008286(insulin receptor signaling pathway);GO:0009267(cellular response to starvation);GO:0009749(response to glucose);GO:0014070(response to organic cyclic compound);GO:0019217(regulation of fatty acid metabolic process);GO:0030324(lung development);GO:0031065(positive regulation of histone deacetylation);GO:0032094(response to food);GO:0032526(response to retinoic acid);GO:0032570(response to progesterone);GO:0032869(cellular response to insulin stimulus);GO:0033762(response to glucagon);GO:0033993(response to lipid);GO:0042493(response to drug);GO:0042789(mRNA transcription from RNA polymerase II promoter);GO:0043434(response to peptide hormone);GO:0045444(fat cell differentiation);GO:0045542(positive regulation of cholesterol biosynthetic process);GO:0045893(positive regulation of transcription, DNA-templated);GO:0046676(negative regulation of insulin secretion);GO:0050796(regulation of insulin secretion);GO:0051591(response to cAMP);GO:0070542(response to fatty acid);GO:0071398(cellular response to fatty acid);GO:0043231(intracellular membrane-bounded organelle);GO:0043234(protein complex);GO:0043234(protein complex)","04152(AMPK signaling pathway);04910(Insulin signaling pathway);04932(Non-alcoholic fatty liver disease (NAFLD));04931(Insulin resistance);04931(Insulin resistance)","K07197","NA","sterol regulatory element binding transcription factor 1 [Source:HGNC Symbol;Acc:HGNC:11289]",{"v":2.32808731992528,"d":"2.33"},{"v":1.23541901046077,"d":"1.24"},{"v":1.88445159108972,"d":"1.88"},{"v":0.914144734672298,"d":"0.91"},{"v":0.330905431250436,"d":"0.33"},{"v":0.840230032960099,"d":"0.84"},"up","no"]
["ENSG00000104177","MYEF2","ENST00000324324;ENST00000561301;ENST00000560530;ENST00000560157;ENST00000560513;ENST00000561351;ENST00000561151;ENST00000616409;ENST00000267836;ENST00000558289","GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0000981(RNA polymerase II transcription factor activity, sequence-specific DNA binding);GO:0003697(single-stranded DNA binding);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0005634(nucleus);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0030182(neuron differentiation);GO:0014902(myotube differentiation);GO:0014902(myotube differentiation)","NA","NA","NA","myelin expression factor 2 [Source:HGNC Symbol;Acc:HGNC:17940]",{"v":0.185561201819862,"d":"0.19"},{"v":0.0961536774010095,"d":"0.10"},{"v":1.9298398858525,"d":"1.93"},{"v":0.948481155540559,"d":"0.95"},{"v":0.331202961669031,"d":"0.33"},{"v":0.840230032960099,"d":"0.84"},"up","no"]
["MSTRG.5841","SEPT1;AC116348.4","ENST00000573615;ENST00000563957;ENST00000321367;ENST00000568577;ENST00000563743;ENST00000566517;ENST00000562152;ENST00000570039;ENST00000624127;ENST00000572252;ENST00000567783","GO:0005525(GTP binding);GO:0000166(nucleotide binding);GO:0007056(spindle assembly involved in female meiosis);GO:0051311(meiotic metaphase plate congression);GO:0030496(midbody);GO:0072687(meiotic spindle);GO:0072687(meiotic spindle)","05100(Bacterial invasion of epithelial cells);05100(Bacterial invasion of epithelial cells)","K13737","NA","septin 1 [Source:HGNC Symbol;Acc:HGNC:2879]",{"v":14.0619553386256,"d":"14.06"},{"v":18.12129065,"d":"18.12"},{"v":0.775990828149186,"d":"0.78"},{"v":-0.36588849435883,"d":"-0.37"},{"v":0.333759374093609,"d":"0.33"},{"v":0.843549269459441,"d":"0.84"},"down","no"]
["ENSG00000166927","MS4A7","ENST00000358246;ENST00000300184;ENST00000528587;ENST00000528808;ENST00000530027;ENST00000528215;ENST00000534016;ENST00000528500;ENST00000533849;ENST00000534310;ENST00000530614","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016021(integral component of membrane)","NA","NA","NA","membrane spanning 4-domains A7 [Source:HGNC Symbol;Acc:HGNC:13378]",{"v":3.09550117778289,"d":"3.10"},{"v":3.9955947925483,"d":"4.00"},{"v":0.774728504390869,"d":"0.77"},{"v":-0.368237273522356,"d":"-0.37"},{"v":0.334721313297053,"d":"0.33"},{"v":0.843549269459441,"d":"0.84"},"down","no"]
["MSTRG.5228","SNAPC5;AC116913.1","ENST00000316634;ENST00000307979;ENST00000568875;ENST00000565387;ENST00000563480;ENST00000395589;ENST00000565465;ENST00000566658","GO:0005634(nucleus);GO:0005730(nucleolus);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0006366(transcription from RNA polymerase II promoter);GO:0005515(protein binding);GO:0016604(nuclear body);GO:0006384(transcription initiation from RNA polymerase III promoter);GO:0005654(nucleoplasm);GO:0042795(snRNA transcription from RNA polymerase II promoter);GO:0042795(snRNA transcription from RNA polymerase II promoter)","NA","NA","NA","small nuclear RNA activating complex polypeptide 5 [Source:HGNC Symbol;Acc:HGNC:15484]",{"v":0.789013943331705,"d":"0.79"},{"v":1.0388473617489,"d":"1.04"},{"v":0.759509021617382,"d":"0.76"},{"v":-0.39686099340509,"d":"-0.40"},{"v":0.335489255072527,"d":"0.34"},{"v":0.843744227847568,"d":"0.84"},"down","no"]
["ENSG00000139714","MORN3","ENST00000355329;ENST00000392462;ENST00000542364","GO:0005634(nucleus);GO:0005515(protein binding);GO:0005515(protein binding)","NA","NA","NA","MORN repeat containing 3 [Source:HGNC Symbol;Acc:HGNC:29807]",{"v":0.498935309387967,"d":"0.50"},{"v":0.2577126968361,"d":"0.26"},{"v":1.93601369087872,"d":"1.94"},{"v":0.953089154933271,"d":"0.95"},{"v":0.337101497699269,"d":"0.34"},{"v":0.844134768880351,"d":"0.84"},"up","no"]
["MSTRG.8024","GMIP","ENST00000587238;ENST00000203556;ENST00000591047;ENST00000587205;ENST00000593186;ENST00000587713;ENST00000586269;ENST00000588171","GO:0034260(negative regulation of GTPase activity);GO:0046872(metal ion binding);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0035556(intracellular signal transduction);GO:0007165(signal transduction);GO:0005886(plasma membrane);GO:0043547(positive regulation of GTPase activity);GO:0005096(GTPase activator activity);GO:0051056(regulation of small GTPase mediated signal transduction);GO:0005622(intracellular);GO:0005515(protein binding);GO:0005515(protein binding)","NA","NA","NA","GEM interacting protein [Source:HGNC Symbol;Acc:HGNC:24852]",{"v":30.9883808796791,"d":"30.99"},{"v":16.6109274510695,"d":"16.61"},{"v":1.86554188325492,"d":"1.87"},{"v":0.899594750444627,"d":"0.90"},{"v":0.337348614688169,"d":"0.34"},{"v":0.844134768880351,"d":"0.84"},"up","no"]
["ENSG00000166928","MS4A14","ENST00000300187;ENST00000534688;ENST00000530662;ENST00000531949;ENST00000525397;ENST00000531783;ENST00000395001;ENST00000531787;ENST00000527841","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016021(integral component of membrane)","NA","NA","NA","membrane spanning 4-domains A14 [Source:HGNC Symbol;Acc:HGNC:30706]",{"v":1.31226026585122,"d":"1.31"},{"v":0.692642130304543,"d":"0.69"},{"v":1.89457182639791,"d":"1.89"},{"v":0.921871835873952,"d":"0.92"},{"v":0.339259034558001,"d":"0.34"},{"v":0.845272509830952,"d":"0.85"},"up","no"]
["MSTRG.6817","NKIRAS2","ENST00000393885;ENST00000316082;ENST00000585955;ENST00000393880;ENST00000307641;ENST00000462043;ENST00000485789;ENST00000449471;ENST00000393879;ENST00000393881;ENST00000491638","GO:0005525(GTP binding);GO:0016020(membrane);GO:0007165(signal transduction);GO:0005737(cytoplasm);GO:0000166(nucleotide binding);GO:0003924(GTPase activity);GO:0005575(cellular_component);GO:0007249(I-kappaB kinase/NF-kappaB signaling);GO:0007249(I-kappaB kinase/NF-kappaB signaling)","NA","NA","NA","NFKB inhibitor interacting Ras like 2 [Source:HGNC Symbol;Acc:HGNC:17898]",{"v":0.999805133668703,"d":"1.00"},{"v":0.534213985986346,"d":"0.53"},{"v":1.87154428730037,"d":"1.87"},{"v":0.904229187865253,"d":"0.90"},{"v":0.339943896774083,"d":"0.34"},{"v":0.845400200793219,"d":"0.85"},"up","no"]
["ENSG00000226287","TMEM191A","ENST00000452055;ENST00000414022;ENST00000422715;ENST00000450925;ENST00000637163;ENST00000442222;ENST00000445836;ENST00000436618;ENST00000428752","NA","NA","NA","NA","transmembrane protein 191A (pseudogene) [Source:HGNC Symbol;Acc:HGNC:25317]",{"v":0.576940478758774,"d":"0.58"},{"v":0.759412794606576,"d":"0.76"},{"v":0.759719197327543,"d":"0.76"},{"v":-0.396461817754035,"d":"-0.40"},{"v":0.341837951966237,"d":"0.34"},{"v":0.847179558131413,"d":"0.85"},"down","no"]
["ENSG00000243696","AC006254.1","ENST00000468472;ENST00000513520","GO:0005634(nucleus);GO:0002062(chondrocyte differentiation);GO:0035988(chondrocyte proliferation);GO:0042246(tissue regeneration);GO:0042246(tissue regeneration)","NA","NA","NA",null,{"v":0.380443414726841,"d":"0.38"},{"v":0.496963931591449,"d":"0.50"},{"v":0.765535264316931,"d":"0.77"},{"v":-0.385459258007045,"d":"-0.39"},{"v":0.343314884500065,"d":"0.34"},{"v":0.847254380995475,"d":"0.85"},"down","no"]
["ENSG00000168661","ZNF30","ENST00000601142;ENST00000439785;ENST00000601540;ENST00000601957;ENST00000303586","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0005622(intracellular);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding)","NA","NA","NA","zinc finger protein 30 [Source:HGNC Symbol;Acc:HGNC:13090]",{"v":0.555655227686703,"d":"0.56"},{"v":0.740856154098361,"d":"0.74"},{"v":0.750017698594875,"d":"0.75"},{"v":-0.415003454780459,"d":"-0.42"},{"v":0.344199551924843,"d":"0.34"},{"v":0.848174604270635,"d":"0.85"},"down","no"]
["MSTRG.7222","SAP30BP","ENST00000584667;ENST00000580322;ENST00000583329;ENST00000579877;ENST00000580601;ENST00000583536;ENST00000578909;ENST00000584557;ENST00000542343;ENST00000577292;ENST00000578756;ENST00000581385;ENST00000582022;ENST00000584861;ENST00000581207;ENST00000293208;ENST00000578288;ENST00000355423","GO:0006355(regulation of transcription, DNA-templated);GO:0005654(nucleoplasm);GO:0045111(intermediate filament cytoskeleton);GO:0005634(nucleus);GO:0006351(transcription, DNA-templated);GO:0005515(protein binding);GO:0006915(apoptotic process);GO:0010942(positive regulation of cell death);GO:0010942(positive regulation of cell death)","NA","NA","NA","SAP30 binding protein [Source:HGNC Symbol;Acc:HGNC:30785]",{"v":3.2005433803822,"d":"3.20"},{"v":4.08413446637639,"d":"4.08"},{"v":0.783652792710778,"d":"0.78"},{"v":-0.351713503284293,"d":"-0.35"},{"v":0.344659946400855,"d":"0.34"},{"v":0.848174604270635,"d":"0.85"},"down","no"]
["MSTRG.1063","AL353807.3","MSTRG.1063.1","NA","NA","NA","NA",null,{"v":5.841343,"d":"5.84"},{"v":7.481597,"d":"7.48"},{"v":0.780761513885338,"d":"0.78"},{"v":-0.357046155069569,"d":"-0.36"},{"v":0.34618914487175,"d":"0.35"},{"v":0.848789727147178,"d":"0.85"},"down","no"]
["MSTRG.11713","SNCA","ENST00000394991;ENST00000394986;ENST00000618500;ENST00000502987;ENST00000420646;ENST00000508895;ENST00000505199;ENST00000336904;ENST00000506244;ENST00000345009;ENST00000394989;ENST00000506691","GO:0006919(activation of cysteine-type endopeptidase activity involved in apoptotic process);GO:0043065(positive regulation of apoptotic process);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0046872(metal ion binding);GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0005829(cytosol);GO:0008270(zinc ion binding);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0000287(magnesium ion binding);GO:0048471(perinuclear region of cytoplasm);GO:0005615(extracellular space);GO:0030054(cell junction);GO:0045202(synapse);GO:0005509(calcium ion binding);GO:0042802(identical protein binding);GO:0098794(postsynapse);GO:0030424(axon);GO:0030426(growth cone);GO:0031648(protein destabilization);GO:0044267(cellular protein metabolic process);GO:0099512(supramolecular fiber);GO:0005938(cell cortex);GO:0032496(response to lipopolysaccharide);GO:0070840(dynein complex binding);GO:0043014(alpha-tubulin binding);GO:0014059(regulation of dopamine secretion);GO:0033138(positive regulation of peptidyl-serine phosphorylation);GO:0043066(negative regulation of apoptotic process);GO:0070555(response to interleukin-1);GO:0042393(histone binding);GO:0005507(copper ion binding);GO:0032410(negative regulation of transporter activity);GO:0005739(mitochondrion);GO:0045807(positive regulation of endocytosis);GO:0043154(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process);GO:0051281(positive regulation of release of sequestered calcium ion into cytosol);GO:0019894(kinesin binding);GO:0010642(negative regulation of platelet-derived growth factor receptor signaling pathway);GO:0015629(actin cytoskeleton);GO:0034341(response to interferon-gamma);GO:0034599(cellular response to oxidative stress);GO:1901215(negative regulation of neuron death);GO:0043027(cysteine-type endopeptidase inhibitor activity involved in apoptotic process);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0048488(synaptic vesicle endocytosis);GO:0031623(receptor internalization);GO:0001921(positive regulation of receptor recycling);GO:0006915(apoptotic process);GO:0097435(supramolecular fiber organization);GO:0048156(tau protein binding);GO:0045920(negative regulation of exocytosis);GO:1903136(cuprous ion binding);GO:0044212(transcription regulatory region DNA binding);GO:0042416(dopamine biosynthetic process);GO:1904715(negative regulation of chaperone-mediated autophagy);GO:0031092(platelet alpha granule membrane);GO:0001774(microglial cell activation);GO:0071280(cellular response to copper ion);GO:0008198(ferrous iron binding);GO:0005764(lysosome);GO:0010040(response to iron(II) ion);GO:0030544(Hsp70 protein binding);GO:0016234(inclusion body);GO:0051219(phosphoprotein binding);GO:0005747(mitochondrial respiratory chain complex I);GO:0005543(phospholipid binding);GO:0008017(microtubule binding);GO:0019899(enzyme binding);GO:0019904(protein domain specific binding);GO:0043274(phospholipase binding);GO:0047485(protein N-terminus binding);GO:0048487(beta-tubulin binding);GO:0001933(negative regulation of protein phosphorylation);GO:0001956(positive regulation of neurotransmitter secretion);GO:0001963(synaptic transmission, dopaminergic);GO:0006631(fatty acid metabolic process);GO:0006638(neutral lipid metabolic process);GO:0006644(phospholipid metabolic process);GO:0007006(mitochondrial membrane organization);GO:0007268(chemical synaptic transmission);GO:0007568(aging);GO:0008344(adult locomotory behavior);GO:0010517(regulation of phospholipase activity);GO:0014048(regulation of glutamate secretion);GO:0031115(negative regulation of microtubule polymerization);GO:0032026(response to magnesium ion);GO:0032769(negative regulation of monooxygenase activity);GO:0035067(negative regulation of histone acetylation);GO:0040012(regulation of locomotion);GO:0042220(response to cocaine);GO:0042417(dopamine metabolic process);GO:0042493(response to drug);GO:0042775(mitochondrial ATP synthesis coupled electron transport);GO:0043030(regulation of macrophage activation);GO:0043524(negative regulation of neuron apoptotic process);GO:0044344(cellular response to fibroblast growth factor stimulus);GO:0045963(negative regulation of dopamine metabolic process);GO:0046928(regulation of neurotransmitter secretion);GO:0048148(behavioral response to cocaine);GO:0048168(regulation of neuronal synaptic plasticity);GO:0048169(regulation of long-term neuronal synaptic plasticity);GO:0048489(synaptic vesicle transport);GO:0050806(positive regulation of synaptic transmission);GO:0050808(synapse organization);GO:0050812(regulation of acyl-CoA biosynthetic process);GO:0051583(dopamine uptake involved in synaptic transmission);GO:0051585(negative regulation of dopamine uptake involved in synaptic transmission);GO:0051612(negative regulation of serotonin uptake);GO:0051622(negative regulation of norepinephrine uptake);GO:0060079(excitatory postsynaptic potential);GO:0060291(long-term synaptic potentiation);GO:0060732(positive regulation of inositol phosphate biosynthetic process);GO:0061024(membrane organization);GO:0070495(negative regulation of thrombin-activated receptor signaling pathway);GO:0071872(cellular response to epinephrine stimulus);GO:0071902(positive regulation of protein serine/threonine kinase activity);GO:1901214(regulation of neuron death);GO:1902957(negative regulation of mitochondrial electron transport, NADH to ubiquinone);GO:1903284(positive regulation of glutathione peroxidase activity);GO:1903285(positive regulation of hydrogen peroxide catabolic process);GO:1903421(regulation of synaptic vesicle recycling);GO:1903426(regulation of reactive oxygen species biosynthetic process);GO:1905606(regulation of presynapse assembly);GO:2000377(regulation of reactive oxygen species metabolic process);GO:0005640(nuclear outer membrane);GO:0005791(rough endoplasmic reticulum);GO:0005794(Golgi apparatus);GO:0005840(ribosome);GO:0005856(cytoskeleton);GO:0008021(synaptic vesicle);GO:0030659(cytoplasmic vesicle membrane);GO:0043025(neuronal cell body);GO:0043195(terminal bouton);GO:0043231(intracellular membrane-bounded organelle);GO:0043679(axon terminus);GO:0043679(axon terminus)","05010(Alzheimer's disease);05012(Parkinson's disease);05012(Parkinson's disease)","K04528","NA","synuclein alpha [Source:HGNC Symbol;Acc:HGNC:11138]",{"v":17.9166592949676,"d":"17.92"},{"v":22.7841868570005,"d":"22.78"},{"v":0.78636377973097,"d":"0.79"},{"v":-0.346731222860358,"d":"-0.35"},{"v":0.34819285301592,"d":"0.35"},{"v":0.850668844508615,"d":"0.85"},"down","no"]
["ENSG00000168060","NAALADL1","ENST00000526516;ENST00000358658;ENST00000526799;ENST00000533842;ENST00000534568;ENST00000533340;ENST00000532432;ENST00000533753;ENST00000529274;ENST00000530139;ENST00000531174;ENST00000531746;ENST00000532802","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0046872(metal ion binding);GO:0016787(hydrolase activity);GO:0005886(plasma membrane);GO:0003824(catalytic activity);GO:0008152(metabolic process);GO:0008233(peptidase activity);GO:0006508(proteolysis);GO:0004180(carboxypeptidase activity);GO:0008237(metallopeptidase activity);GO:0016805(dipeptidase activity);GO:0016324(apical plasma membrane);GO:0016324(apical plasma membrane)","NA","NA","NA","N-acetylated alpha-linked acidic dipeptidase like 1 [Source:HGNC Symbol;Acc:HGNC:23536]",{"v":0.628494980217606,"d":"0.63"},{"v":0.811600545499505,"d":"0.81"},{"v":0.774389548778327,"d":"0.77"},{"v":-0.36886861286812,"d":"-0.37"},{"v":0.348969696797142,"d":"0.35"},{"v":0.851562321686322,"d":"0.85"},"down","no"]
["MSTRG.4203","TRAV24","ENST00000390453","NA","NA","NA","NA","T-cell receptor alpha variable 24 [Source:HGNC Symbol;Acc:HGNC:12121]",{"v":2.501616,"d":"2.50"},{"v":3.289956,"d":"3.29"},{"v":0.760379774076006,"d":"0.76"},{"v":-0.395207937740888,"d":"-0.40"},{"v":0.351300810611034,"d":"0.35"},{"v":0.852870904560235,"d":"0.85"},"down","no"]
["MSTRG.8542","TP53I3","ENST00000335934;ENST00000407482;ENST00000413037;ENST00000238721;ENST00000470636","GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0042803(protein homodimerization activity);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0042981(regulation of apoptotic process);GO:0070402(NADPH binding);GO:0003960(NADPH:quinone reductase activity);GO:0006739(NADP metabolic process);GO:0048038(quinone binding);GO:0048038(quinone binding)","04115(p53 signaling pathway);04115(p53 signaling pathway)","K10133","EC:1.-.-.-","tumor protein p53 inducible protein 3 [Source:HGNC Symbol;Acc:HGNC:19373]",{"v":0.968258541522491,"d":"0.97"},{"v":1.25196156098616,"d":"1.25"},{"v":0.773393186896091,"d":"0.77"},{"v":-0.370726039639796,"d":"-0.37"},{"v":0.352498033247336,"d":"0.35"},{"v":0.853536209362243,"d":"0.85"},"down","no"]
["MSTRG.10939","APEH","MSTRG.10939.13;ENST00000296456;ENST00000482301;ENST00000457042;ENST00000442186;ENST00000491799;ENST00000462439;ENST00000483715;ENST00000463616;ENST00000463995;ENST00000438011;ENST00000447436;ENST00000480772;ENST00000447541;ENST00000446089","GO:0003723(RNA binding);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0016787(hydrolase activity);GO:0031965(nuclear membrane);GO:0005515(protein binding);GO:0006508(proteolysis);GO:0004252(serine-type endopeptidase activity);GO:0008236(serine-type peptidase activity);GO:0005576(extracellular region);GO:0042802(identical protein binding);GO:0070062(extracellular exosome);GO:0043312(neutrophil degranulation);GO:1904813(ficolin-1-rich granule lumen);GO:0050435(amyloid-beta metabolic process);GO:0008242(omega peptidase activity);GO:0006415(translational termination);GO:0006415(translational termination)","NA","NA","NA","acylaminoacyl-peptide hydrolase [Source:HGNC Symbol;Acc:HGNC:586]",{"v":9.12243031569929,"d":"9.12"},{"v":11.5575722336689,"d":"11.56"},{"v":0.789303335619596,"d":"0.79"},{"v":-0.34134824877696,"d":"-0.34"},{"v":0.353145781599349,"d":"0.35"},{"v":0.853706595023652,"d":"0.85"},"down","no"]
["ENSG00000108433","GOSR2","ENST00000640051;ENST00000638838;ENST00000225567;ENST00000570879;ENST00000639713;ENST00000638634;ENST00000415811;ENST00000640792;ENST00000640608;ENST00000640621;ENST00000575949;ENST00000640495;ENST00000571658;ENST00000638219;ENST00000638579;ENST00000640269;ENST00000571048;ENST00000638216;ENST00000640871;ENST00000640709;ENST00000639031;ENST00000638892;ENST00000640443;ENST00000639080;ENST00000640866;ENST00000638374;ENST00000639287;ENST00000640711;ENST00000573224;ENST00000640068;ENST00000393456","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0006810(transport);GO:0005794(Golgi apparatus);GO:0005484(SNAP receptor activity);GO:0061025(membrane fusion);GO:0015031(protein transport);GO:0016192(vesicle-mediated transport);GO:0005829(cytosol);GO:0005515(protein binding);GO:0000139(Golgi membrane);GO:0031902(late endosome membrane);GO:0006891(intra-Golgi vesicle-mediated transport);GO:0005789(endoplasmic reticulum membrane);GO:0000149(SNARE binding);GO:0006623(protein targeting to vacuole);GO:0006888(ER to Golgi vesicle-mediated transport);GO:0006896(Golgi to vacuole transport);GO:0042147(retrograde transport, endosome to Golgi);GO:0048280(vesicle fusion with Golgi apparatus);GO:0012507(ER to Golgi transport vesicle membrane);GO:0031201(SNARE complex);GO:0048208(COPII vesicle coating);GO:0036498(IRE1-mediated unfolded protein response);GO:0033116(endoplasmic reticulum-Golgi intermediate compartment membrane);GO:0033116(endoplasmic reticulum-Golgi intermediate compartment membrane)","04130(SNARE interactions in vesicular transport);04130(SNARE interactions in vesicular transport)","K08496","NA","golgi SNAP receptor complex member 2 [Source:HGNC Symbol;Acc:HGNC:4431]",{"v":1.40810849283029,"d":"1.41"},{"v":1.77927920771265,"d":"1.78"},{"v":0.791392653118496,"d":"0.79"},{"v":-0.337534422751768,"d":"-0.34"},{"v":0.355412795806493,"d":"0.36"},{"v":0.855602661580476,"d":"0.86"},"down","no"]
["MSTRG.8287","GRWD1;CYTH2;KCNJ14;AC008403.1","ENST00000253237;ENST00000427476;ENST00000641098;ENST00000452733;ENST00000467412;ENST00000600597;ENST00000595765;ENST00000391884;ENST00000325139;ENST00000595676;ENST00000599949;ENST00000462117;ENST00000474049;ENST00000493260;ENST00000460595","GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005730(nucleolus);GO:0005829(cytosol);GO:0006334(nucleosome assembly);GO:0005694(chromosome);GO:0006260(DNA replication);GO:0005515(protein binding);GO:0003682(chromatin binding);GO:0043234(protein complex);GO:0042393(histone binding);GO:0003688(DNA replication origin binding);GO:0006337(nucleosome disassembly);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005886(plasma membrane);GO:0043547(positive regulation of GTPase activity);GO:0042995(cell projection);GO:0005086(ARF guanyl-nucleotide exchange factor activity);GO:0032012(regulation of ARF protein signal transduction);GO:0005085(guanyl-nucleotide exchange factor activity);GO:0008289(lipid binding);GO:0030426(growth cone);GO:0000139(Golgi membrane);GO:0030036(actin cytoskeleton organization);GO:0006897(endocytosis);GO:0070679(inositol 1,4,5 trisphosphate binding);GO:0006810(transport);GO:0016021(integral component of membrane);GO:0005244(voltage-gated ion channel activity);GO:0006811(ion transport);GO:0006813(potassium ion transport);GO:0034765(regulation of ion transmembrane transport);GO:0005242(inward rectifier potassium channel activity);GO:0010107(potassium ion import);GO:0061337(cardiac conduction);GO:0008076(voltage-gated potassium channel complex);GO:0030425(dendrite);GO:0043025(neuronal cell body);GO:0070679(inositol 1,4,5 trisphosphate binding)","04072(Phospholipase D signaling pathway);04144(Endocytosis);04921(Oxytocin signaling pathway);04725(Cholinergic synapse);04144(Endocytosis)","K18441","NA","glutamate rich WD repeat containing 1 [Source:HGNC Symbol;Acc:HGNC:21270];cytohesin 2 [Source:HGNC Symbol;Acc:HGNC:9502];potassium voltage-gated channel subfamily J member 14 [Source:HGNC Symbol;Acc:HGNC:6260]",{"v":1.70877041013394,"d":"1.71"},{"v":2.16187581694528,"d":"2.16"},{"v":0.790410992500219,"d":"0.79"},{"v":-0.339325083800709,"d":"-0.34"},{"v":0.356215014623142,"d":"0.36"},{"v":0.855711260576734,"d":"0.86"},"down","no"]
["ENSG00000143458","GABPB2","ENST00000368918;ENST00000368916;ENST00000489549;ENST00000486076;ENST00000462520","GO:0005634(nucleus);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0005515(protein binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0046982(protein heterodimerization activity);GO:0044212(transcription regulatory region DNA binding);GO:0042803(protein homodimerization activity);GO:0042803(protein homodimerization activity)","NA","NA","NA","GA binding protein transcription factor beta subunit 2 [Source:HGNC Symbol;Acc:HGNC:28441]",{"v":1.79116056067037,"d":"1.79"},{"v":0.973795987267385,"d":"0.97"},{"v":1.83935915129064,"d":"1.84"},{"v":0.879203206338404,"d":"0.88"},{"v":0.357473465004977,"d":"0.36"},{"v":0.856476036538642,"d":"0.86"},"up","no"]
["MSTRG.3885","MPHOSPH8","ENST00000496525;ENST00000361479;ENST00000467481;ENST00000414242;ENST00000449056","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005730(nucleolus);GO:0005829(cytosol);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0016567(protein ubiquitination);GO:0005886(plasma membrane);GO:0005694(chromosome);GO:0005515(protein binding);GO:0004842(ubiquitin-protein transferase activity);GO:0031625(ubiquitin protein ligase binding);GO:0000151(ubiquitin ligase complex);GO:0070062(extracellular exosome);GO:0045892(negative regulation of transcription, DNA-templated);GO:0035064(methylated histone binding);GO:0000788(nuclear nucleosome);GO:0005720(nuclear heterochromatin);GO:0044030(regulation of DNA methylation);GO:0044030(regulation of DNA methylation)","NA","NA","NA","M-phase phosphoprotein 8 [Source:HGNC Symbol;Acc:HGNC:29810]",{"v":7.64861743853211,"d":"7.65"},{"v":4.17399949989806,"d":"4.17"},{"v":1.83244330496899,"d":"1.83"},{"v":0.873768562667191,"d":"0.87"},{"v":0.358897374672508,"d":"0.36"},{"v":0.856926070371576,"d":"0.86"},"up","no"]
["ENSG00000138778","CENPE","ENST00000265148;ENST00000380026;ENST00000509120","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0005829(cytosol);GO:0051301(cell division);GO:0005694(chromosome);GO:0015630(microtubule cytoskeleton);GO:0003777(microtubule motor activity);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0007049(cell cycle);GO:0008017(microtubule binding);GO:0007059(chromosome segregation);GO:0007275(multicellular organism development);GO:0005874(microtubule);GO:0007018(microtubule-based movement);GO:0005819(spindle);GO:0030496(midbody);GO:0000775(chromosome, centromeric region);GO:0000776(kinetochore);GO:0000777(condensed chromosome kinetochore);GO:0043515(kinetochore binding);GO:0007080(mitotic metaphase plate congression);GO:0051315(attachment of mitotic spindle microtubules to kinetochore);GO:0006890(retrograde vesicle-mediated transport, Golgi to ER);GO:0016887(ATPase activity);GO:0007062(sister chromatid cohesion);GO:0019886(antigen processing and presentation of exogenous peptide antigen via MHC class II);GO:0005871(kinesin complex);GO:1990023(mitotic spindle midzone);GO:0000278(mitotic cell cycle);GO:0051310(metaphase plate congression);GO:0045860(positive regulation of protein kinase activity);GO:0000940(condensed chromosome outer kinetochore);GO:0051382(kinetochore assembly);GO:0007079(mitotic chromosome movement towards spindle pole);GO:0030071(regulation of mitotic metaphase/anaphase transition);GO:0099607(lateral attachment of mitotic spindle microtubules to kinetochore);GO:0000779(condensed chromosome, centromeric region);GO:0003774(motor activity);GO:0005623(cell);GO:0005623(cell)","NA","NA","NA","centromere protein E [Source:HGNC Symbol;Acc:HGNC:1856]",{"v":0.128621004235493,"d":"0.13"},{"v":0.166638187632359,"d":"0.17"},{"v":0.771857916021384,"d":"0.77"},{"v":-0.373592794954816,"d":"-0.37"},{"v":0.361201167346379,"d":"0.36"},{"v":0.859691648233248,"d":"0.86"},"down","no"]
["MSTRG.7378","METRNL","ENST00000320095;ENST00000571940;ENST00000574053;ENST00000570778;ENST00000571814","GO:0005576(extracellular region);GO:0005615(extracellular space);GO:0005179(hormone activity);GO:0003674(molecular_function);GO:0070062(extracellular exosome);GO:0045444(fat cell differentiation);GO:0050728(negative regulation of inflammatory response);GO:0014850(response to muscle activity);GO:0050873(brown fat cell differentiation);GO:0009409(response to cold);GO:0090336(positive regulation of brown fat cell differentiation);GO:2000507(positive regulation of energy homeostasis);GO:2000507(positive regulation of energy homeostasis)","NA","NA","NA","meteorin like, glial cell differentiation regulator [Source:HGNC Symbol;Acc:HGNC:27584]",{"v":5.86276933358721,"d":"5.86"},{"v":7.39001972886519,"d":"7.39"},{"v":0.793336086869621,"d":"0.79"},{"v":-0.333995919827114,"d":"-0.33"},{"v":0.362073842206939,"d":"0.36"},{"v":0.859694035892289,"d":"0.86"},"down","no"]
["ENSG00000162694","EXTL2","ENST00000494907;ENST00000370114;ENST00000535414;ENST00000370113;ENST00000480774","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0046872(metal ion binding);GO:0016740(transferase activity);GO:0016757(transferase activity, transferring glycosyl groups);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005576(extracellular region);GO:0070062(extracellular exosome);GO:0036498(IRE1-mediated unfolded protein response);GO:0001888(glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity);GO:0015012(heparan sulfate proteoglycan biosynthetic process);GO:0006044(N-acetylglucosamine metabolic process);GO:0019276(UDP-N-acetylgalactosamine metabolic process);GO:0035248(alpha-1,4-N-acetylgalactosaminyltransferase activity);GO:0005539(glycosaminoglycan binding);GO:0030145(manganese ion binding);GO:0047237(glucuronylgalactosylproteoglycan 4-beta-N-acetylgalactosaminyltransferase activity);GO:0047237(glucuronylgalactosylproteoglycan 4-beta-N-acetylgalactosaminyltransferase activity)","00534(Glycosaminoglycan biosynthesis - heparan sulfate / heparin);00534(Glycosaminoglycan biosynthesis - heparan sulfate / heparin)","K02369","EC:2.4.1.223","exostosin like glycosyltransferase 2 [Source:HGNC Symbol;Acc:HGNC:3516]",{"v":0.275553524203558,"d":"0.28"},{"v":0.360147892014895,"d":"0.36"},{"v":0.765112139521177,"d":"0.77"},{"v":-0.386256881363711,"d":"-0.39"},{"v":0.362311110154589,"d":"0.36"},{"v":0.859730061754237,"d":"0.86"},"down","no"]
["MSTRG.8297","FTL","ENST00000331825","GO:0016020(membrane);GO:0046872(metal ion binding);GO:0005515(protein binding);GO:0008199(ferric iron binding);GO:0006826(iron ion transport);GO:0006879(cellular iron ion homeostasis);GO:0005506(iron ion binding);GO:0005576(extracellular region);GO:0042802(identical protein binding);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0043312(neutrophil degranulation);GO:0035578(azurophil granule lumen);GO:0055072(iron ion homeostasis);GO:0006880(intracellular sequestering of iron ion);GO:0008043(intracellular ferritin complex);GO:0044754(autolysosome)","04216(Ferroptosis);04217(Necroptosis);04978(Mineral absorption)","K13625","NA","ferritin light chain [Source:HGNC Symbol;Acc:HGNC:3999]",{"v":1245.008179,"d":"1245.01"},{"v":1559.501099,"d":"1559.50"},{"v":0.798337481004879,"d":"0.80"},{"v":-0.324929349382299,"d":"-0.32"},{"v":0.364723004198088,"d":"0.36"},{"v":0.860617172124598,"d":"0.86"},"down","no"]
["ENSG00000104447","TRPS1","ENST00000395715;ENST00000220888;ENST00000640765;ENST00000518018;ENST00000519076","GO:0005634(nucleus);GO:0003676(nucleic acid binding);GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0005654(nucleoplasm);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0043565(sequence-specific DNA binding);GO:0005515(protein binding);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0003682(chromatin binding);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0005667(transcription factor complex);GO:0000977(RNA polymerase II regulatory region sequence-specific DNA binding);GO:0001228(transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding);GO:0030154(cell differentiation);GO:0000790(nuclear chromatin);GO:0006366(transcription from RNA polymerase II promoter);GO:0043234(protein complex);GO:0019904(protein domain specific binding);GO:0001501(skeletal system development);GO:0006607(NLS-bearing protein import into nucleus);GO:0001227(transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding);GO:0001085(RNA polymerase II transcription factor binding);GO:0051291(protein heterooligomerization);GO:0032330(regulation of chondrocyte differentiation);GO:0032330(regulation of chondrocyte differentiation)","NA","NA","NA","transcriptional repressor GATA binding 1 [Source:HGNC Symbol;Acc:HGNC:12340]",{"v":0.741697691473988,"d":"0.74"},{"v":0.40382210982659,"d":"0.40"},{"v":1.83669411214876,"d":"1.84"},{"v":0.877111376241379,"d":"0.88"},{"v":0.365663270535831,"d":"0.37"},{"v":0.860617172124598,"d":"0.86"},"up","no"]
["MSTRG.6954","MRPL10","ENST00000351111;ENST00000290208;ENST00000414011;ENST00000466016;ENST00000480901;ENST00000421763","GO:0003723(RNA binding);GO:0006412(translation);GO:0005654(nucleoplasm);GO:0005739(mitochondrion);GO:0030529(intracellular ribonucleoprotein complex);GO:0005622(intracellular);GO:0005840(ribosome);GO:0005515(protein binding);GO:0003735(structural constituent of ribosome);GO:0042254(ribosome biogenesis);GO:0032543(mitochondrial translation);GO:0005743(mitochondrial inner membrane);GO:0070125(mitochondrial translational elongation);GO:0070126(mitochondrial translational termination);GO:0005762(mitochondrial large ribosomal subunit);GO:0005762(mitochondrial large ribosomal subunit)","03010(Ribosome);03010(Ribosome)","K02864","NA","mitochondrial ribosomal protein L10 [Source:HGNC Symbol;Acc:HGNC:14055]",{"v":5.45418349710564,"d":"5.45"},{"v":6.84151916678727,"d":"6.84"},{"v":0.797218185630968,"d":"0.80"},{"v":-0.326953474499193,"d":"-0.33"},{"v":0.366091532301043,"d":"0.37"},{"v":0.860670348625795,"d":"0.86"},"down","no"]
["ENSG00000197969","VPS13A","ENST00000360280;ENST00000471439;ENST00000493341;ENST00000419472;ENST00000355766;ENST00000376634;ENST00000357409;ENST00000467124;ENST00000484581","GO:0006810(transport);GO:0015031(protein transport);GO:0005829(cytosol);GO:0005515(protein binding);GO:0005622(intracellular);GO:0006895(Golgi to endosome transport);GO:0008104(protein localization);GO:0006914(autophagy);GO:0007399(nervous system development);GO:0007626(locomotory behavior);GO:0035176(social behavior);GO:0031045(dense core granule);GO:0031045(dense core granule)","NA","NA","NA","vacuolar protein sorting 13 homolog A [Source:HGNC Symbol;Acc:HGNC:1908]",{"v":1.60290287769855,"d":"1.60"},{"v":0.880320285254506,"d":"0.88"},{"v":1.82081783703887,"d":"1.82"},{"v":0.864586595710492,"d":"0.86"},{"v":0.366746107227325,"d":"0.37"},{"v":0.861158558957476,"d":"0.86"},"up","no"]
["MSTRG.15055","UCK1","ENST00000372215;ENST00000459858;ENST00000491309;ENST00000372208;ENST00000484876;ENST00000372211;ENST00000482398;ENST00000494584;ENST00000372210","GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0008152(metabolic process);GO:0019206(nucleoside kinase activity);GO:0004849(uridine kinase activity);GO:0044206(UMP salvage);GO:0044211(CTP salvage);GO:0005829(cytosol);GO:0043097(pyrimidine nucleoside salvage);GO:0006206(pyrimidine nucleobase metabolic process);GO:0009165(nucleotide biosynthetic process);GO:0009165(nucleotide biosynthetic process)","00240(Pyrimidine metabolism);00983(Drug metabolism - other enzymes);00983(Drug metabolism - other enzymes)","K00876","EC:2.7.1.48","uridine-cytidine kinase 1 [Source:HGNC Symbol;Acc:HGNC:14859]",{"v":4.73725976078869,"d":"4.74"},{"v":5.93412540885417,"d":"5.93"},{"v":0.798307995601228,"d":"0.80"},{"v":-0.324982634154972,"d":"-0.32"},{"v":0.368430990729031,"d":"0.37"},{"v":0.862308780384096,"d":"0.86"},"down","no"]
["MSTRG.3826","HCAR3;HCAR2","MSTRG.3826.1;MSTRG.3826.2;ENST00000528880;MSTRG.3826.3;ENST00000328880","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0004930(G-protein coupled receptor activity);GO:0007186(G-protein coupled receptor signaling pathway);GO:0005886(plasma membrane);GO:0030054(cell junction);GO:0004871(signal transducer activity);GO:0007165(signal transduction);GO:0005887(integral component of plasma membrane);GO:0006915(apoptotic process);GO:0001781(neutrophil apoptotic process);GO:0050995(negative regulation of lipid catabolic process);GO:0070553(nicotinic acid receptor activity);GO:0033031(positive regulation of neutrophil apoptotic process);GO:0070165(positive regulation of adiponectin secretion)","04024(cAMP signaling pathway);04024(cAMP signaling pathway)","K08402","NA","hydroxycarboxylic acid receptor 3 [Source:HGNC Symbol;Acc:HGNC:16824];hydroxycarboxylic acid receptor 2 [Source:HGNC Symbol;Acc:HGNC:24827]",{"v":38.2607574146492,"d":"38.26"},{"v":21.1126389850226,"d":"21.11"},{"v":1.81222051122039,"d":"1.81"},{"v":0.857758513379875,"d":"0.86"},{"v":0.370002875844297,"d":"0.37"},{"v":0.862492238509672,"d":"0.86"},"up","no"]
["MSTRG.14880",null,"MSTRG.14880.1","NA","NA","NA","NA",null,{"v":3.908294,"d":"3.91"},{"v":2.121296,"d":"2.12"},{"v":1.84240860304267,"d":"1.84"},{"v":0.881593052857604,"d":"0.88"},{"v":0.370847540923532,"d":"0.37"},{"v":0.862492238509672,"d":"0.86"},"up","no"]
["MSTRG.14742","SIGMAR1","ENST00000277010;ENST00000353468;ENST00000478146;ENST00000477726;ENST00000497006;ENST00000461426","GO:0006810(transport);GO:0005634(nucleus);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005886(plasma membrane);GO:0042995(cell projection);GO:0006869(lipid transport);GO:0030054(cell junction);GO:0045202(synapse);GO:0045211(postsynaptic membrane);GO:0031410(cytoplasmic vesicle);GO:0038003(opioid receptor signaling pathway);GO:0030426(growth cone);GO:0005637(nuclear inner membrane);GO:0014069(postsynaptic density);GO:0005887(integral component of plasma membrane);GO:0005811(lipid particle);GO:0005635(nuclear envelope);GO:0070207(protein homotrimerization);GO:0005640(nuclear outer membrane);GO:0043523(regulation of neuron apoptotic process);GO:0008144(drug binding);GO:0004872(receptor activity);GO:0004985(opioid receptor activity);GO:0007399(nervous system development);GO:0007399(nervous system development)","NA","NA","NA","sigma non-opioid intracellular receptor 1 [Source:HGNC Symbol;Acc:HGNC:8157]",{"v":5.37046804143898,"d":"5.37"},{"v":6.7223999075592,"d":"6.72"},{"v":0.798891484483093,"d":"0.80"},{"v":-0.323928543461573,"d":"-0.32"},{"v":0.372410412727179,"d":"0.37"},{"v":0.863922451033582,"d":"0.86"},"down","no"]
["ENSG00000135336","ORC3","ENST00000257789;ENST00000392844;ENST00000468486;ENST00000508875;ENST00000478028","GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0016604(nuclear body);GO:0006260(DNA replication);GO:0005664(nuclear origin of replication recognition complex);GO:0000784(nuclear chromosome, telomeric region);GO:0000082(G1/S transition of mitotic cell cycle);GO:0006270(DNA replication initiation);GO:0003688(DNA replication origin binding);GO:0000808(origin recognition complex);GO:0006267(pre-replicative complex assembly involved in nuclear cell cycle DNA replication);GO:0005656(nuclear pre-replicative complex);GO:0031261(DNA replication preinitiation complex);GO:0061351(neural precursor cell proliferation);GO:0061351(neural precursor cell proliferation)","04110(Cell cycle);04110(Cell cycle)","K02605","NA","origin recognition complex subunit 3 [Source:HGNC Symbol;Acc:HGNC:8489]",{"v":2.6981682081865,"d":"2.70"},{"v":3.37482217918135,"d":"3.37"},{"v":0.799499370613064,"d":"0.80"},{"v":-0.322831196908795,"d":"-0.32"},{"v":0.373002775328541,"d":"0.37"},{"v":0.863978852609787,"d":"0.86"},"down","no"]
["ENSG00000203797","DDO","ENST00000368923;ENST00000368924","GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0048037(cofactor binding);GO:0003884(D-amino-acid oxidase activity);GO:0071949(FAD binding);GO:0046416(D-amino acid metabolic process);GO:0005777(peroxisome);GO:0005515(protein binding);GO:0034641(cellular nitrogen compound metabolic process);GO:0005102(receptor binding);GO:0005782(peroxisomal matrix);GO:0008445(D-aspartate oxidase activity);GO:0006531(aspartate metabolic process);GO:0007320(insemination);GO:0007625(grooming behavior);GO:0019478(D-amino acid catabolic process);GO:0042445(hormone metabolic process);GO:0042445(hormone metabolic process)","00250(Alanine, aspartate and glutamate metabolism);04146(Peroxisome);04146(Peroxisome)","K00272","EC:1.4.3.1","D-aspartate oxidase [Source:HGNC Symbol;Acc:HGNC:2727]",{"v":0.349391642253521,"d":"0.35"},{"v":0.451512,"d":"0.45"},{"v":0.773825816929608,"d":"0.77"},{"v":-0.369919233080909,"d":"-0.37"},{"v":0.37440449531024,"d":"0.37"},{"v":0.864377158721989,"d":"0.86"},"down","no"]
["ENSG00000162601","MYSM1","ENST00000472487;ENST00000493821;ENST00000481973;ENST00000401044;ENST00000483003;ENST00000622766;ENST00000489282","GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0005654(nucleoplasm);GO:0004843(thiol-dependent ubiquitin-specific protease activity);GO:0016787(hydrolase activity);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0016569(covalent chromatin modification);GO:0003677(DNA binding);GO:0005886(plasma membrane);GO:0008233(peptidase activity);GO:0006508(proteolysis);GO:0036459(thiol-dependent ubiquitinyl hydrolase activity);GO:0008237(metallopeptidase activity);GO:0003713(transcription coactivator activity);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0016579(protein deubiquitination);GO:0042393(histone binding);GO:0006338(chromatin remodeling);GO:0032403(protein complex binding);GO:0030334(regulation of cell migration);GO:0035522(monoubiquitinated histone H2A deubiquitination);GO:0043473(pigmentation);GO:0051797(regulation of hair follicle development);GO:0051797(regulation of hair follicle development)","NA","NA","NA","Myb like, SWIRM and MPN domains 1 [Source:HGNC Symbol;Acc:HGNC:29401]",{"v":4.09194947829492,"d":"4.09"},{"v":2.26811499004252,"d":"2.27"},{"v":1.80411905756957,"d":"1.80"},{"v":0.851294548181734,"d":"0.85"},{"v":0.37703697844976,"d":"0.38"},{"v":0.866828448745686,"d":"0.87"},"up","no"]
["ENSG00000228696","ARL17B","ENST00000450673;ENST00000572991;ENST00000622877;ENST00000570618;ENST00000575698;ENST00000434041;ENST00000575960;ENST00000571246","GO:0006810(transport);GO:0015031(protein transport);GO:0005525(GTP binding);GO:0007264(small GTPase mediated signal transduction);GO:0000166(nucleotide binding);GO:0005794(Golgi apparatus);GO:0005622(intracellular);GO:0016192(vesicle-mediated transport);GO:0016192(vesicle-mediated transport)","NA","NA","NA","ADP ribosylation factor like GTPase 17B [Source:HGNC Symbol;Acc:HGNC:32387]",{"v":0.866732190566485,"d":"0.87"},{"v":0.472809840483527,"d":"0.47"},{"v":1.83315175860153,"d":"1.83"},{"v":0.874326225222581,"d":"0.87"},{"v":0.3775699755549,"d":"0.38"},{"v":0.866828448745686,"d":"0.87"},"up","no"]
["MSTRG.1917","HIF1AN","ENST00000299163;ENST00000533589;ENST00000478787;ENST00000526476;ENST00000528044","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0008270(zinc ion binding);GO:0042803(protein homodimerization activity);GO:0005515(protein binding);GO:0048037(cofactor binding);GO:0048471(perinuclear region of cytoplasm);GO:0051213(dioxygenase activity);GO:0005506(iron ion binding);GO:0016706(oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors);GO:0061418(regulation of transcription from RNA polymerase II promoter in response to hypoxia);GO:0005112(Notch binding);GO:0051059(NF-kappaB binding);GO:0045746(negative regulation of Notch signaling pathway);GO:2001214(positive regulation of vasculogenesis);GO:0045663(positive regulation of myoblast differentiation);GO:0061428(negative regulation of transcription from RNA polymerase II promoter in response to hypoxia);GO:0031406(carboxylic acid binding);GO:0019826(oxygen sensor activity);GO:0071532(ankyrin repeat binding);GO:0036139(peptidyl-histidine dioxygenase activity);GO:0036140(peptidyl-asparagine 3-dioxygenase activity);GO:0102113(-);GO:0036138(peptidyl-histidine hydroxylation);GO:0042264(peptidyl-aspartic acid hydroxylation);GO:0042265(peptidyl-asparagine hydroxylation);GO:0042265(peptidyl-asparagine hydroxylation)","NA","NA","NA","hypoxia inducible factor 1 alpha subunit inhibitor [Source:HGNC Symbol;Acc:HGNC:17113]",{"v":4.72894100157706,"d":"4.73"},{"v":2.62789858387097,"d":"2.63"},{"v":1.7995142699195,"d":"1.80"},{"v":0.847607542696356,"d":"0.85"},{"v":0.379449971880753,"d":"0.38"},{"v":0.867815231274195,"d":"0.87"},"up","no"]
["MSTRG.8080","PSENEN;LIN37","ENST00000587708;ENST00000301159;ENST00000590890;ENST00000591076;ENST00000587751;ENST00000595455;ENST00000587108;ENST00000591949;ENST00000592871;ENST00000222266;ENST00000590706","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005794(Golgi apparatus);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0007219(Notch signaling pathway);GO:0032580(Golgi cisterna membrane);GO:0048013(ephrin receptor signaling pathway);GO:0007220(Notch receptor processing);GO:0043065(positive regulation of apoptotic process);GO:0005887(integral component of plasma membrane);GO:0042982(amyloid precursor protein metabolic process);GO:0031293(membrane protein intracellular domain proteolysis);GO:0070765(gamma-secretase complex);GO:0006509(membrane protein ectodomain proteolysis);GO:0016485(protein processing);GO:0034205(amyloid-beta formation);GO:0042987(amyloid precursor protein catabolic process);GO:0043085(positive regulation of catalytic activity);GO:0017053(transcriptional repressor complex);GO:0007049(cell cycle);GO:0005654(nucleoplasm);GO:0051726(regulation of cell cycle);GO:0051726(regulation of cell cycle)","04330(Notch signaling pathway);05010(Alzheimer's disease);04218(Cellular senescence);04218(Cellular senescence)","K06170;K21774","NA","presenilin enhancer gamma-secretase subunit [Source:HGNC Symbol;Acc:HGNC:30100];lin-37 DREAM MuvB core complex component [Source:HGNC Symbol;Acc:HGNC:33234]",{"v":3.07327327588424,"d":"3.07"},{"v":3.81724879249732,"d":"3.82"},{"v":0.805101643341838,"d":"0.81"},{"v":-0.312757161239964,"d":"-0.31"},{"v":0.379899617923958,"d":"0.38"},{"v":0.867815231274195,"d":"0.87"},"down","no"]
["MSTRG.652","PIGK","ENST00000370812;ENST00000359130;ENST00000478391;ENST00000445065","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016787(hydrolase activity);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0008233(peptidase activity);GO:0008234(cysteine-type peptidase activity);GO:0006508(proteolysis);GO:0003756(protein disulfide isomerase activity);GO:0006506(GPI anchor biosynthetic process);GO:0005515(protein binding);GO:0016255(attachment of GPI anchor to protein);GO:0042765(GPI-anchor transamidase complex);GO:0003923(GPI-anchor transamidase activity);GO:0030176(integral component of endoplasmic reticulum membrane);GO:0034235(GPI anchor binding);GO:0034394(protein localization to cell surface);GO:0034394(protein localization to cell surface)","00563(Glycosylphosphatidylinositol(GPI)-anchor biosynthesis);00563(Glycosylphosphatidylinositol(GPI)-anchor biosynthesis)","K05290","EC:2.6.-.-","phosphatidylinositol glycan anchor biosynthesis class K [Source:HGNC Symbol;Acc:HGNC:8965]",{"v":3.18141170868855,"d":"3.18"},{"v":3.93450562325413,"d":"3.93"},{"v":0.808592492506666,"d":"0.81"},{"v":-0.306515286125249,"d":"-0.31"},{"v":0.381185578329529,"d":"0.38"},{"v":0.867815231274195,"d":"0.87"},"down","no"]
["MSTRG.10193","IGLV7-46","ENST00000390295","GO:0016020(membrane);GO:0005886(plasma membrane);GO:0005576(extracellular region);GO:0002376(immune system process);GO:0002377(immunoglobulin production);GO:0006955(immune response);GO:0005615(extracellular space);GO:0003823(antigen binding);GO:0002250(adaptive immune response)","NA","NA","NA","immunoglobulin lambda variable 7-46 (gene/pseudogene) [Source:HGNC Symbol;Acc:HGNC:5930]",{"v":7.499911,"d":"7.50"},{"v":9.37649,"d":"9.38"},{"v":0.7998633817132,"d":"0.80"},{"v":-0.322174489082759,"d":"-0.32"},{"v":0.382482404040958,"d":"0.38"},{"v":0.867915677174684,"d":"0.87"},"down","no"]
["MSTRG.6355","KIF1C","ENST00000320785;ENST00000573815;ENST00000572959","GO:0003723(RNA binding);GO:0005737(cytoplasm);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0003777(microtubule motor activity);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0008017(microtubule binding);GO:0005874(microtubule);GO:0007018(microtubule-based movement);GO:0030705(cytoskeleton-dependent intracellular transport);GO:0016887(ATPase activity);GO:0003774(motor activity);GO:0005871(kinesin complex);GO:0005783(endoplasmic reticulum);GO:0005794(Golgi apparatus);GO:0006890(retrograde vesicle-mediated transport, Golgi to ER);GO:0006890(retrograde vesicle-mediated transport, Golgi to ER)","NA","NA","NA","kinesin family member 1C [Source:HGNC Symbol;Acc:HGNC:6317]",{"v":3.02864366655012,"d":"3.03"},{"v":1.68544785967366,"d":"1.69"},{"v":1.79693702725193,"d":"1.80"},{"v":0.845539851216674,"d":"0.85"},{"v":0.382916213584113,"d":"0.38"},{"v":0.868252763706188,"d":"0.87"},"up","no"]
["MSTRG.5548","TBC1D24;AMDHD2;ATP6V0C;AC093525.1;AC093525.2","ENST00000567020;ENST00000302956;ENST00000330398;ENST00000293971;ENST00000564973;ENST00000568263;ENST00000569317;ENST00000561487;ENST00000563453;ENST00000563444;ENST00000564543;ENST00000568562;ENST00000569879;ENST00000636980;ENST00000630263;ENST00000565570;ENST00000569219;ENST00000565963;ENST00000566947;ENST00000563145;ENST00000413459;ENST00000565223;ENST00000570028;ENST00000562105;ENST00000293970;ENST00000566853;ENST00000627285;ENST00000566706","GO:0005737(cytoplasm);GO:0005886(plasma membrane);GO:0030054(cell junction);GO:0043547(positive regulation of GTPase activity);GO:0005096(GTPase activator activity);GO:0005515(protein binding);GO:0031175(neuron projection development);GO:0043195(terminal bouton);GO:0031594(neuromuscular junction);GO:0016787(hydrolase activity);GO:0016810(hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0005975(carbohydrate metabolic process);GO:0006044(N-acetylglucosamine metabolic process);GO:0005829(cytosol);GO:0006046(N-acetylglucosamine catabolic process);GO:0006048(UDP-N-acetylglucosamine biosynthetic process);GO:0019262(N-acetylneuraminate catabolic process);GO:0008448(N-acetylglucosamine-6-phosphate deacetylase activity);GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005765(lysosomal membrane);GO:0006811(ion transport);GO:0015078(hydrogen ion transmembrane transporter activity);GO:0015991(ATP hydrolysis coupled proton transport);GO:0015992(proton transport);GO:0033179(proton-transporting V-type ATPase, V0 domain);GO:0005925(focal adhesion);GO:0070062(extracellular exosome);GO:0034220(ion transmembrane transport);GO:0010008(endosome membrane);GO:0016032(viral process);GO:0031625(ubiquitin protein ligase binding);GO:0043312(neutrophil degranulation);GO:0070821(tertiary granule membrane);GO:0033177(proton-transporting two-sector ATPase complex, proton-transporting domain);GO:0005773(vacuole);GO:0005774(vacuolar membrane);GO:0030670(phagocytic vesicle membrane);GO:0035577(azurophil granule membrane);GO:0046961(proton-transporting ATPase activity, rotational mechanism);GO:0008286(insulin receptor signaling pathway);GO:0016241(regulation of macroautophagy);GO:0033572(transferrin transport);GO:0090383(phagosome acidification);GO:0101003(ficolin-1-rich granule membrane);GO:0030177(positive regulation of Wnt signaling pathway);GO:0046933(proton-transporting ATP synthase activity, rotational mechanism);GO:0007042(lysosomal lumen acidification);GO:0000220(vacuolar proton-transporting V-type ATPase, V0 domain);GO:0050775(positive regulation of dendrite morphogenesis);GO:2000463(positive regulation of excitatory postsynaptic potential);GO:2001224(positive regulation of neuron migration);GO:0008448(N-acetylglucosamine-6-phosphate deacetylase activity)","00520(Amino sugar and nucleotide sugar metabolism);00190(Oxidative phosphorylation);04145(Phagosome);04142(Lysosome);04966(Collecting duct acid secretion);04721(Synaptic vesicle cycle);05323(Rheumatoid arthritis);05110(Vibrio cholerae infection);05120(Epithelial cell signaling in Helicobacter pylori infection);05152(Tuberculosis);00520(Amino sugar and nucleotide sugar metabolism)","K01443;K02155","EC:3.5.1.25","TBC1 domain family member 24 [Source:HGNC Symbol;Acc:HGNC:29203];amidohydrolase domain containing 2 [Source:HGNC Symbol;Acc:HGNC:24262];ATPase H+ transporting V0 subunit c [Source:HGNC Symbol;Acc:HGNC:855]",{"v":8.52768218739975,"d":"8.53"},{"v":4.76678179772111,"d":"4.77"},{"v":1.78898102520167,"d":"1.79"},{"v":0.839138085549332,"d":"0.84"},{"v":0.384822965902938,"d":"0.38"},{"v":0.869317213434585,"d":"0.87"},"up","no"]
["ENSG00000139974","SLC38A6","ENST00000526539;ENST00000267488;ENST00000528350;ENST00000491344;ENST00000525723;ENST00000554072;ENST00000534758;ENST00000451406;ENST00000529345;ENST00000354886","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0006811(ion transport);GO:0005886(plasma membrane);GO:0006814(sodium ion transport);GO:0005887(integral component of plasma membrane);GO:0015171(amino acid transmembrane transporter activity);GO:0003333(amino acid transmembrane transport);GO:0006865(amino acid transport);GO:0006865(amino acid transport)","NA","NA","NA","solute carrier family 38 member 6 [Source:HGNC Symbol;Acc:HGNC:19863]",{"v":0.344544794249077,"d":"0.34"},{"v":0.43306326151156,"d":"0.43"},{"v":0.795599222724368,"d":"0.80"},{"v":-0.329886228183085,"d":"-0.33"},{"v":0.385451831946747,"d":"0.39"},{"v":0.869681780531878,"d":"0.87"},"down","no"]
["ENSG00000188647","PTAR1","ENST00000377200;ENST00000340434;ENST00000472967;ENST00000467511;ENST00000474925;ENST00000415701","GO:0008318(protein prenyltransferase activity);GO:0018342(protein prenylation);GO:0016740(transferase activity);GO:0005737(cytoplasm);GO:0004659(prenyltransferase activity);GO:1990234(transferase complex);GO:1990234(transferase complex)","NA","NA","NA","protein prenyltransferase alpha subunit repeat containing 1 [Source:HGNC Symbol;Acc:HGNC:30449]",{"v":5.12317947418033,"d":"5.12"},{"v":2.86883915122951,"d":"2.87"},{"v":1.78580227196937,"d":"1.79"},{"v":0.836572350872888,"d":"0.84"},{"v":0.387736666409976,"d":"0.39"},{"v":0.871292411763337,"d":"0.87"},"up","no"]
["MSTRG.2508","PRDX5","ENST00000265462;ENST00000352435;ENST00000347941","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0005739(mitochondrion);GO:0045454(cell redox homeostasis);GO:0048471(perinuclear region of cytoplasm);GO:0005615(extracellular space);GO:0031410(cytoplasmic vesicle);GO:0098869(cellular oxidant detoxification);GO:0006954(inflammatory response);GO:0005777(peroxisome);GO:0004601(peroxidase activity);GO:0043231(intracellular membrane-bounded organelle);GO:0070062(extracellular exosome);GO:0005759(mitochondrial matrix);GO:0005102(receptor binding);GO:0016480(negative regulation of transcription from RNA polymerase III promoter);GO:0043066(negative regulation of apoptotic process);GO:0006979(response to oxidative stress);GO:0034599(cellular response to oxidative stress);GO:0043027(cysteine-type endopeptidase inhibitor activity involved in apoptotic process);GO:0043154(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process);GO:0046983(protein dimerization activity);GO:0016209(antioxidant activity);GO:0006915(apoptotic process);GO:0034614(cellular response to reactive oxygen species);GO:0051920(peroxiredoxin activity);GO:0001016(RNA polymerase III regulatory region DNA binding);GO:0008379(thioredoxin peroxidase activity);GO:0008379(thioredoxin peroxidase activity)","04146(Peroxisome);04146(Peroxisome)","K11187","EC:1.11.1.15","peroxiredoxin 5 [Source:HGNC Symbol;Acc:HGNC:9355]",{"v":58.4132934389698,"d":"58.41"},{"v":71.7816537558791,"d":"71.78"},{"v":0.813763550748308,"d":"0.81"},{"v":-0.297318432726307,"d":"-0.30"},{"v":0.388081157797494,"d":"0.39"},{"v":0.871292411763337,"d":"0.87"},"down","no"]
["MSTRG.12427","RBM27;POU4F3;AC091959.3","ENST00000265271;ENST00000230732;ENST00000508019;ENST00000506502","GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016607(nuclear speck);GO:0046872(metal ion binding);GO:0006397(mRNA processing);GO:0005654(nucleoplasm);GO:0006355(regulation of transcription, DNA-templated);GO:0006366(transcription from RNA polymerase II promoter);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0007605(sensory perception of sound);GO:0043565(sequence-specific DNA binding);GO:0030154(cell differentiation);GO:0048839(inner ear development);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0007601(visual perception);GO:0001077(transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0001228(transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0021562(vestibulocochlear nerve development);GO:0031290(retinal ganglion cell axon guidance);GO:0042472(inner ear morphogenesis);GO:0042491(auditory receptor cell differentiation);GO:0048675(axon extension);GO:0050885(neuromuscular process controlling balance);GO:0051402(neuron apoptotic process);GO:0060113(inner ear receptor cell differentiation);GO:0006397(mRNA processing)","NA","NA","NA","RNA binding motif protein 27 [Source:HGNC Symbol;Acc:HGNC:29243];POU class 4 homeobox 3 [Source:HGNC Symbol;Acc:HGNC:9220]",{"v":3.94416149358652,"d":"3.94"},{"v":2.20690204087022,"d":"2.21"},{"v":1.78719373154926,"d":"1.79"},{"v":0.837696030795851,"d":"0.84"},{"v":0.390057957231533,"d":"0.39"},{"v":0.87193950602059,"d":"0.87"},"up","no"]
["MSTRG.3135","AC092490.1","MSTRG.3135.1;ENST00000540299;ENST00000422780","NA","NA","NA","NA",null,{"v":11.7908912783392,"d":"11.79"},{"v":14.4548862866872,"d":"14.45"},{"v":0.815702804192828,"d":"0.82"},{"v":-0.293884483151538,"d":"-0.29"},{"v":0.391112965837719,"d":"0.39"},{"v":0.872144881863292,"d":"0.87"},"down","no"]
["MSTRG.11274","SELENOT","ENST00000477889;ENST00000471696;ENST00000615547;ENST00000466234;ENST00000485923","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0045454(cell redox homeostasis);GO:0007204(positive regulation of cytosolic calcium ion concentration);GO:0042593(glucose homeostasis);GO:0009749(response to glucose);GO:0060124(positive regulation of growth hormone secretion);GO:0008430(selenium binding);GO:0098869(cellular oxidant detoxification);GO:0004791(thioredoxin-disulfide reductase activity);GO:0001514(selenocysteine incorporation);GO:0031016(pancreas development);GO:0035773(insulin secretion involved in cellular response to glucose stimulus);GO:0035773(insulin secretion involved in cellular response to glucose stimulus)","NA","NA","NA","selenoprotein T [Source:HGNC Symbol;Acc:HGNC:18136]",{"v":18.3405233064087,"d":"18.34"},{"v":22.4665051828295,"d":"22.47"},{"v":0.816349635030277,"d":"0.82"},{"v":-0.292740917334759,"d":"-0.29"},{"v":0.392181930074715,"d":"0.39"},{"v":0.872459358630752,"d":"0.87"},"down","no"]
["ENSG00000157077","ZFYVE9","ENST00000287727","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0043231(intracellular membrane-bounded organelle);GO:0046872(metal ion binding);GO:0005829(cytosol);GO:0005515(protein binding);GO:0006508(proteolysis);GO:0008236(serine-type peptidase activity);GO:0005768(endosome);GO:0006897(endocytosis);GO:0005769(early endosome);GO:0031901(early endosome membrane);GO:0043234(protein complex);GO:0019904(protein domain specific binding);GO:0007179(transforming growth factor beta receptor signaling pathway);GO:0005545(1-phosphatidylinositol binding);GO:0007183(SMAD protein complex assembly);GO:0007184(SMAD protein import into nucleus)","04350(TGF-beta signaling pathway);04144(Endocytosis)","K04679","NA","zinc finger FYVE-type containing 9 [Source:HGNC Symbol;Acc:HGNC:6775]",{"v":0.474721228094336,"d":"0.47"},{"v":0.262448555000861,"d":"0.26"},{"v":1.80881631484989,"d":"1.81"},{"v":0.855045909833039,"d":"0.86"},{"v":0.394192315043674,"d":"0.39"},{"v":0.874142434168771,"d":"0.87"},"up","no"]
["MSTRG.7832","ELOF1","ENST00000252445;ENST00000586683;ENST00000590700;ENST00000587806;ENST00000593077;ENST00000591674;ENST00000586120;ENST00000591912;ENST00000589171","GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003746(translation elongation factor activity);GO:0006414(translational elongation);GO:0005515(protein binding);GO:0006368(transcription elongation from RNA polymerase II promoter);GO:0000993(RNA polymerase II core binding);GO:0048096(chromatin-mediated maintenance of transcription);GO:0008023(transcription elongation factor complex);GO:0008023(transcription elongation factor complex)","NA","NA","NA","elongation factor 1 homolog [Source:HGNC Symbol;Acc:HGNC:28691]",{"v":4.76317287658759,"d":"4.76"},{"v":5.8331825971723,"d":"5.83"},{"v":0.81656502213673,"d":"0.82"},{"v":-0.292360324373836,"d":"-0.29"},{"v":0.394549979502871,"d":"0.39"},{"v":0.874142434168771,"d":"0.87"},"down","no"]
["MSTRG.13075","GTPBP2","ENST00000307126;ENST00000480263;ENST00000496137;ENST00000476510;ENST00000442748;ENST00000307114;ENST00000432918;ENST00000459959;ENST00000419497","GO:0043231(intracellular membrane-bounded organelle);GO:0005525(GTP binding);GO:0000166(nucleotide binding);GO:0003924(GTPase activity);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0008150(biological_process);GO:0002576(platelet degranulation);GO:0031093(platelet alpha granule lumen);GO:0031093(platelet alpha granule lumen)","NA","NA","NA","GTP binding protein 2 [Source:HGNC Symbol;Acc:HGNC:4670]",{"v":7.58439316933391,"d":"7.58"},{"v":9.27377374891869,"d":"9.27"},{"v":0.817832456848351,"d":"0.82"},{"v":-0.290122775475051,"d":"-0.29"},{"v":0.396233718957547,"d":"0.40"},{"v":0.87463592754521,"d":"0.87"},"down","no"]
["ENSG00000178700","DHFR2","ENST00000314636;ENST00000394221;ENST00000481631","GO:0016020(membrane);GO:0009165(nucleotide biosynthetic process);GO:0016491(oxidoreductase activity);GO:0050661(NADP binding);GO:0055114(oxidation-reduction process);GO:0005739(mitochondrion);GO:0005743(mitochondrial inner membrane);GO:0006730(one-carbon metabolic process);GO:0005759(mitochondrial matrix);GO:0006545(glycine biosynthetic process);GO:0003729(mRNA binding);GO:0004146(dihydrofolate reductase activity);GO:0046653(tetrahydrofolate metabolic process);GO:0046654(tetrahydrofolate biosynthetic process);GO:0046105(thymidine biosynthetic process);GO:0046105(thymidine biosynthetic process)","00790(Folate biosynthesis);00670(One carbon pool by folate);01523(Antifolate resistance);01523(Antifolate resistance)","K00287","EC:1.5.1.3","dihydrofolate reductase 2 [Source:HGNC Symbol;Acc:HGNC:27309]",{"v":1.63136415132003,"d":"1.63"},{"v":0.911731107533805,"d":"0.91"},{"v":1.7893040369466,"d":"1.79"},{"v":0.839398549674317,"d":"0.84"},{"v":0.396736725772165,"d":"0.40"},{"v":0.87463592754521,"d":"0.87"},"up","no"]
["MSTRG.6544","LGALS9DP","ENST00000580112","NA","NA","NA","NA","galectin 9D, pseudogene [Source:HGNC Symbol;Acc:HGNC:49896]",{"v":3.88151,"d":"3.88"},{"v":2.140105,"d":"2.14"},{"v":1.8137007296371,"d":"1.81"},{"v":0.858936423072883,"d":"0.86"},{"v":0.398341977225154,"d":"0.40"},{"v":0.875568155542537,"d":"0.88"},"up","no"]
["MSTRG.9593","MKKS","ENST00000347364;ENST00000399054","GO:0005737(cytoplasm);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0005829(cytosol);GO:0006457(protein folding);GO:0005813(centrosome);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0051082(unfolded protein binding);GO:0060271(cilium assembly);GO:0050896(response to stimulus);GO:0005815(microtubule organizing center);GO:0061077(chaperone-mediated protein folding);GO:0007601(visual perception);GO:0036064(ciliary basal body);GO:0001947(heart looping);GO:0007368(determination of left/right symmetry);GO:0005622(intracellular);GO:0021987(cerebral cortex development);GO:0045444(fat cell differentiation);GO:0045494(photoreceptor cell maintenance);GO:0007507(heart development);GO:0031514(motile cilium);GO:0044183(protein binding involved in protein folding);GO:0006458('de novo' protein folding);GO:0007608(sensory perception of smell);GO:0035176(social behavior);GO:0008406(gonad development);GO:0048854(brain morphogenesis);GO:0021766(hippocampus development);GO:0060027(convergent extension involved in gastrulation);GO:0001103(RNA polymerase II repressing transcription factor binding);GO:0032402(melanosome transport);GO:0051877(pigment granule aggregation in cell center);GO:0007286(spermatid development);GO:0021756(striatum development);GO:0038108(negative regulation of appetite by leptin-mediated signaling pathway);GO:0046907(intracellular transport);GO:0060296(regulation of cilium beat frequency involved in ciliary motility);GO:0010629(negative regulation of gene expression);GO:0014824(artery smooth muscle contraction);GO:0030837(negative regulation of actin filament polymerization);GO:0033210(leptin-mediated signaling pathway);GO:0034260(negative regulation of GTPase activity);GO:0040018(positive regulation of multicellular organism growth);GO:0042311(vasodilation);GO:0044321(response to leptin);GO:0045776(negative regulation of blood pressure);GO:0050910(detection of mechanical stimulus involved in sensory perception of sound);GO:0051131(chaperone-mediated protein complex assembly);GO:0051216(cartilage development);GO:0051492(regulation of stress fiber assembly);GO:0060324(face development);GO:1905515(non-motile cilium assembly);GO:1902636(kinociliary basal body);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016021(integral component of membrane)","NA","NA","NA","McKusick-Kaufman syndrome [Source:HGNC Symbol;Acc:HGNC:7108]",{"v":2.62400820264634,"d":"2.62"},{"v":3.1974041740256,"d":"3.20"},{"v":0.820668285843468,"d":"0.82"},{"v":-0.285128892461697,"d":"-0.29"},{"v":0.399941115120894,"d":"0.40"},{"v":0.875568155542537,"d":"0.88"},"down","no"]
["MSTRG.5485","RHOT2","ENST00000315082;MSTRG.5485.8;ENST00000602564;ENST00000562598;ENST00000568636;ENST00000562333;ENST00000563134;ENST00000569943;ENST00000570092;ENST00000569358;ENST00000561983;ENST00000565004;ENST00000566214;ENST00000567589;ENST00000566965;ENST00000561711;ENST00000564659;ENST00000567017;ENST00000568950;ENST00000569675;ENST00000569706;ENST00000563637;ENST00000561929;ENST00000562957;ENST00000562708;ENST00000563776","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005525(GTP binding);GO:0007264(small GTPase mediated signal transduction);GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0016787(hydrolase activity);GO:0005509(calcium ion binding);GO:0003924(GTPase activity);GO:0005739(mitochondrion);GO:0005515(protein binding);GO:0005741(mitochondrial outer membrane);GO:0007005(mitochondrion organization);GO:0005886(plasma membrane);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0051056(regulation of small GTPase mediated signal transduction);GO:0047497(mitochondrion transport along microtubule);GO:0031307(integral component of mitochondrial outer membrane);GO:0019725(cellular homeostasis);GO:0097345(mitochondrial outer membrane permeabilization);GO:0097345(mitochondrial outer membrane permeabilization)","04137(Mitophagy - animal);04137(Mitophagy - animal)","K07871","EC:3.6.5.-","ras homolog family member T2 [Source:HGNC Symbol;Acc:HGNC:21169]",{"v":5.76924755102435,"d":"5.77"},{"v":7.03211055431001,"d":"7.03"},{"v":0.82041479673387,"d":"0.82"},{"v":-0.285574582857421,"d":"-0.29"},{"v":0.400113540686344,"d":"0.40"},{"v":0.875568155542537,"d":"0.88"},"down","no"]
["MSTRG.6147","KARS","ENST00000302445;ENST00000319410;ENST00000568682;ENST00000566249;ENST00000568378;ENST00000564578;ENST00000566772;ENST00000566560;ENST00000570215;ENST00000569298;ENST00000562875;ENST00000565738","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0006412(translation);GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0005829(cytosol);GO:0008033(tRNA processing);GO:0005739(mitochondrion);GO:0042803(protein homodimerization activity);GO:0005886(plasma membrane);GO:0016874(ligase activity);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0004812(aminoacyl-tRNA ligase activity);GO:0006418(tRNA aminoacylation for protein translation);GO:0000049(tRNA binding);GO:0005759(mitochondrial matrix);GO:0016032(viral process);GO:0045893(positive regulation of transcription, DNA-templated);GO:0017101(aminoacyl-tRNA synthetase multienzyme complex);GO:0005615(extracellular space);GO:0070371(ERK1 and ERK2 cascade);GO:0070374(positive regulation of ERK1 and ERK2 cascade);GO:0008285(negative regulation of cell proliferation);GO:1900745(positive regulation of p38MAPK cascade);GO:0033209(tumor necrosis factor-mediated signaling pathway);GO:0000187(activation of MAPK activity);GO:0015966(diadenosine tetraphosphate biosynthetic process);GO:0003877(ATP adenylyltransferase activity);GO:0004824(lysine-tRNA ligase activity);GO:0016597(amino acid binding);GO:0002276(basophil activation involved in immune response);GO:0002741(positive regulation of cytokine secretion involved in immune response);GO:0006430(lysyl-tRNA aminoacylation);GO:0010165(response to X-ray);GO:0010759(positive regulation of macrophage chemotaxis);GO:0043032(positive regulation of macrophage activation);GO:1900017(positive regulation of cytokine production involved in inflammatory response);GO:1905050(positive regulation of metallopeptidase activity);GO:1905050(positive regulation of metallopeptidase activity)","00970(Aminoacyl-tRNA biosynthesis);00970(Aminoacyl-tRNA biosynthesis)","K04567","EC:6.1.1.6","lysyl-tRNA synthetase [Source:HGNC Symbol;Acc:HGNC:6215]",{"v":14.3894026376384,"d":"14.39"},{"v":17.4990662804428,"d":"17.50"},{"v":0.822295453199134,"d":"0.82"},{"v":-0.282271243219101,"d":"-0.28"},{"v":0.400964634667851,"d":"0.40"},{"v":0.875568155542537,"d":"0.88"},"down","no"]
["ENSG00000132300","PTCD3","ENST00000254630;ENST00000464541;ENST00000465560;ENST00000480102;ENST00000493430;ENST00000487043;ENST00000494323;ENST00000469585;ENST00000477520;ENST00000472044;ENST00000488801;ENST00000467273;ENST00000476215;ENST00000483925;ENST00000484203;ENST00000418628","GO:0003723(RNA binding);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0005739(mitochondrion);GO:0030529(intracellular ribonucleoprotein complex);GO:0005840(ribosome);GO:0005886(plasma membrane);GO:0032543(mitochondrial translation);GO:0006417(regulation of translation);GO:0019843(rRNA binding);GO:0005515(protein binding);GO:0005743(mitochondrial inner membrane);GO:0043024(ribosomal small subunit binding);GO:0070125(mitochondrial translational elongation);GO:0070126(mitochondrial translational termination);GO:0070126(mitochondrial translational termination)","NA","NA","NA","pentatricopeptide repeat domain 3 [Source:HGNC Symbol;Acc:HGNC:24717]",{"v":2.36707128551751,"d":"2.37"},{"v":2.8785517594451,"d":"2.88"},{"v":0.822313261434567,"d":"0.82"},{"v":-0.282239999491985,"d":"-0.28"},{"v":0.402635731479279,"d":"0.40"},{"v":0.876189735351183,"d":"0.88"},"down","no"]
["MSTRG.5438","MAN2A2","MSTRG.5438.6;ENST00000559717;ENST00000558161;ENST00000560451;ENST00000559341;ENST00000561047;ENST00000360468;ENST00000561046;ENST00000559374;ENST00000560534;ENST00000558171;ENST00000558538;ENST00000558640;ENST00000558374;ENST00000560880;ENST00000560192;ENST00000559999;ENST00000560147;ENST00000558290;ENST00000559132;ENST00000557990;ENST00000559558;ENST00000559965;ENST00000560505;ENST00000560926;ENST00000561448;ENST00000557865","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0046872(metal ion binding);GO:0030246(carbohydrate binding);GO:0016787(hydrolase activity);GO:0003824(catalytic activity);GO:0005975(carbohydrate metabolic process);GO:0008152(metabolic process);GO:0016798(hydrolase activity, acting on glycosyl bonds);GO:0004559(alpha-mannosidase activity);GO:0006013(mannose metabolic process);GO:0005794(Golgi apparatus);GO:0000139(Golgi membrane);GO:0006486(protein glycosylation);GO:0006517(protein deglycosylation);GO:0006491(N-glycan processing);GO:0004572(mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity);GO:0015923(mannosidase activity);GO:0016799(hydrolase activity, hydrolyzing N-glycosyl compounds);GO:0016799(hydrolase activity, hydrolyzing N-glycosyl compounds)","00510(N-Glycan biosynthesis);00510(N-Glycan biosynthesis)","K01231","EC:3.2.1.114","mannosidase alpha class 2A member 2 [Source:HGNC Symbol;Acc:HGNC:6825]",{"v":8.0660714158211,"d":"8.07"},{"v":4.57414812649,"d":"4.57"},{"v":1.76340406842282,"d":"1.76"},{"v":0.818363093328574,"d":"0.82"},{"v":0.40374625652821,"d":"0.40"},{"v":0.876358713695243,"d":"0.88"},"up","no"]
["MSTRG.6491","DRG2","ENST00000225729;ENST00000577771;ENST00000473213;ENST00000579601;ENST00000584212;ENST00000580055;ENST00000578173;ENST00000578767;ENST00000580929;ENST00000579224;ENST00000582419;ENST00000582314;ENST00000582528;ENST00000583355;ENST00000482564;ENST00000395726;ENST00000467099;ENST00000497744","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0043231(intracellular membrane-bounded organelle);GO:0005525(GTP binding);GO:0000166(nucleotide binding);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0005515(protein binding);GO:0007165(signal transduction);GO:0005739(mitochondrion);GO:0005739(mitochondrion)","NA","NA","NA","developmentally regulated GTP binding protein 2 [Source:HGNC Symbol;Acc:HGNC:3030]",{"v":1.84916618917825,"d":"1.85"},{"v":2.25064121576036,"d":"2.25"},{"v":0.82161749115286,"d":"0.82"},{"v":-0.283461199829495,"d":"-0.28"},{"v":0.404288203334948,"d":"0.40"},{"v":0.876586800845547,"d":"0.88"},"down","no"]
["MSTRG.10224","PPM1F;TOP3B","ENST00000397495;ENST00000623652;ENST00000444502;ENST00000436282;ENST00000496143;ENST00000434517;ENST00000470338;ENST00000357179;ENST00000437103;ENST00000487485;ENST00000407142;ENST00000445205;ENST00000497072;ENST00000484588;ENST00000398793;ENST00000424647;ENST00000449704;MSTRG.10224.1;ENST00000442653;ENST00000489581;ENST00000457179","GO:0046872(metal ion binding);GO:0016787(hydrolase activity);GO:0003824(catalytic activity);GO:0006470(protein dephosphorylation);GO:0005829(cytosol);GO:0004721(phosphoprotein phosphatase activity);GO:0005515(protein binding);GO:0006915(apoptotic process);GO:0004722(protein serine/threonine phosphatase activity);GO:0043169(cation binding);GO:0010628(positive regulation of gene expression);GO:0043234(protein complex);GO:0045892(negative regulation of transcription, DNA-templated);GO:0035690(cellular response to drug);GO:0043280(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process);GO:0097193(intrinsic apoptotic signaling pathway);GO:0006469(negative regulation of protein kinase activity);GO:0051496(positive regulation of stress fiber assembly);GO:0035970(peptidyl-threonine dephosphorylation);GO:0010634(positive regulation of epithelial cell migration);GO:0045927(positive regulation of growth);GO:0016791(phosphatase activity);GO:0010811(positive regulation of cell-substrate adhesion);GO:0050921(positive regulation of chemotaxis);GO:0051894(positive regulation of focal adhesion assembly);GO:0044387(negative regulation of protein kinase activity by regulation of protein phosphorylation);GO:0033137(negative regulation of peptidyl-serine phosphorylation);GO:0033192(calmodulin-dependent protein phosphatase activity);GO:0016576(histone dephosphorylation);GO:0048471(perinuclear region of cytoplasm);GO:0003723(RNA binding);GO:0016853(isomerase activity);GO:0003677(DNA binding);GO:0003916(DNA topoisomerase activity);GO:0003917(DNA topoisomerase type I activity);GO:0006265(DNA topological change);GO:0005634(nucleus);GO:0007059(chromosome segregation);GO:0000793(condensed chromosome);GO:0000793(condensed chromosome)","03440(Homologous recombination);03460(Fanconi anemia pathway);03460(Fanconi anemia pathway)","K03165","EC:5.99.1.2","protein phosphatase, Mg2+/Mn2+ dependent 1F [Source:HGNC Symbol;Acc:HGNC:19388];topoisomerase (DNA) III beta [Source:HGNC Symbol;Acc:HGNC:11993]",{"v":7.80961089547172,"d":"7.81"},{"v":4.44533763214269,"d":"4.45"},{"v":1.75680939036062,"d":"1.76"},{"v":0.812957670857441,"d":"0.81"},{"v":0.407407116423676,"d":"0.41"},{"v":0.878702415846286,"d":"0.88"},"up","no"]
["ENSG00000163006","CCDC138","ENST00000409529;ENST00000295124;ENST00000412964;ENST00000609740","NA","NA","NA","NA","coiled-coil domain containing 138 [Source:HGNC Symbol;Acc:HGNC:26531]",{"v":0.216331050379572,"d":"0.22"},{"v":0.265921980331263,"d":"0.27"},{"v":0.813513234634027,"d":"0.81"},{"v":-0.297762278325064,"d":"-0.30"},{"v":0.408487175824323,"d":"0.41"},{"v":0.879325441970725,"d":"0.88"},"down","no"]
["ENSG00000101868","POLA1","ENST00000379068;ENST00000480125","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0016740(transferase activity);GO:0003677(DNA binding);GO:0090305(nucleic acid phosphodiester bond hydrolysis);GO:0006270(DNA replication initiation);GO:0000166(nucleotide binding);GO:0008408(3'-5' exonuclease activity);GO:0006260(DNA replication);GO:0016779(nucleotidyltransferase activity);GO:0003887(DNA-directed DNA polymerase activity);GO:0051536(iron-sulfur cluster binding);GO:0051539(4 iron, 4 sulfur cluster binding);GO:0071897(DNA biosynthetic process);GO:0001882(nucleoside binding);GO:0046982(protein heterodimerization activity);GO:0005658(alpha DNA polymerase:primase complex);GO:0005737(cytoplasm);GO:0005515(protein binding);GO:0005730(nucleolus);GO:0019901(protein kinase binding);GO:0003682(chromatin binding);GO:0008283(cell proliferation);GO:0016032(viral process);GO:0006269(DNA replication, synthesis of RNA primer);GO:0000785(chromatin);GO:0016363(nuclear matrix);GO:0000082(G1/S transition of mitotic cell cycle);GO:0006303(double-strand break repair via nonhomologous end joining);GO:0005635(nuclear envelope);GO:0000083(regulation of transcription involved in G1/S transition of mitotic cell cycle);GO:0006271(DNA strand elongation involved in DNA replication);GO:0006272(leading strand elongation);GO:0006273(lagging strand elongation);GO:0032201(telomere maintenance via semi-conservative replication);GO:0032201(telomere maintenance via semi-conservative replication)","00230(Purine metabolism);00240(Pyrimidine metabolism);03030(DNA replication);03030(DNA replication)","K02320","EC:2.7.7.7","DNA polymerase alpha 1, catalytic subunit [Source:HGNC Symbol;Acc:HGNC:9173]",{"v":1.04854465214646,"d":"1.05"},{"v":0.593249944444444,"d":"0.59"},{"v":1.7674584919319,"d":"1.77"},{"v":0.821676334306431,"d":"0.82"},{"v":0.409178098646429,"d":"0.41"},{"v":0.879843467963003,"d":"0.88"},"up","no"]
["MSTRG.7990","LRRC25","ENST00000339007;ENST00000595840","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005515(protein binding);GO:0005515(protein binding)","NA","NA","NA","leucine rich repeat containing 25 [Source:HGNC Symbol;Acc:HGNC:29806]",{"v":69.90292553706,"d":"69.90"},{"v":39.8994600149068,"d":"39.90"},{"v":1.75197673128768,"d":"1.75"},{"v":0.808983614049364,"d":"0.81"},{"v":0.410645365908997,"d":"0.41"},{"v":0.879851344005894,"d":"0.88"},"up","no"]
["MSTRG.91","TNFRSF14","ENST00000355716;ENST00000451778;ENST00000435221;ENST00000496064;ENST00000409119;ENST00000434817;ENST00000463471;ENST00000466750;ENST00000480305;ENST00000482074;ENST00000463835;ENST00000442392;ENST00000426449;ENST00000482602","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0002741(positive regulation of cytokine secretion involved in immune response);GO:0046642(negative regulation of alpha-beta T cell proliferation);GO:0050731(positive regulation of peptidyl-tyrosine phosphorylation);GO:0050829(defense response to Gram-negative bacterium);GO:0050830(defense response to Gram-positive bacterium);GO:2000406(positive regulation of T cell migration);GO:0009897(external side of plasma membrane);GO:0005515(protein binding);GO:0005886(plasma membrane);GO:0005887(integral component of plasma membrane);GO:0006954(inflammatory response);GO:0046718(viral entry into host cell);GO:0097190(apoptotic signaling pathway);GO:0033209(tumor necrosis factor-mediated signaling pathway);GO:0016032(viral process);GO:0031625(ubiquitin protein ligase binding);GO:0006955(immune response);GO:0007275(multicellular organism development);GO:0032496(response to lipopolysaccharide);GO:0042127(regulation of cell proliferation);GO:0007166(cell surface receptor signaling pathway);GO:0042981(regulation of apoptotic process);GO:0001618(virus receptor activity);GO:0031295(T cell costimulation);GO:0005031(tumor necrosis factor-activated receptor activity);GO:0005031(tumor necrosis factor-activated receptor activity)","04060(Cytokine-cytokine receptor interaction);05168(Herpes simplex infection);05168(Herpes simplex infection)","K05152","NA","TNF receptor superfamily member 14 [Source:HGNC Symbol;Acc:HGNC:11912]",{"v":10.5197406909471,"d":"10.52"},{"v":12.6792742862197,"d":"12.68"},{"v":0.829680031638746,"d":"0.83"},{"v":-0.269373030437997,"d":"-0.27"},{"v":0.411427571983782,"d":"0.41"},{"v":0.879851344005894,"d":"0.88"},"down","no"]
["MSTRG.13902","HBP1","ENST00000222574;ENST00000498408;ENST00000468410;ENST00000478930;ENST00000463202;ENST00000607681;ENST00000464009;MSTRG.13902.5;ENST00000485846;ENST00000479011;ENST00000483809;ENST00000468116;ENST00000497535;ENST00000468401;ENST00000463790","GO:0003723(RNA binding);GO:0005634(nucleus);GO:0016607(nuclear speck);GO:0005654(nucleoplasm);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0016055(Wnt signaling pathway);GO:0007050(cell cycle arrest);GO:0007050(cell cycle arrest)","NA","NA","NA","HMG-box transcription factor 1 [Source:HGNC Symbol;Acc:HGNC:23200]",{"v":12.5929930692808,"d":"12.59"},{"v":15.1687837475202,"d":"15.17"},{"v":0.830191350795644,"d":"0.83"},{"v":-0.268484193335185,"d":"-0.27"},{"v":0.412523520757161,"d":"0.41"},{"v":0.879851344005894,"d":"0.88"},"down","no"]
["ENSG00000069966","GNB5","ENST00000358784;ENST00000560085;ENST00000557936;ENST00000559348;ENST00000560075;ENST00000558122;ENST00000396335;ENST00000561313;ENST00000559541;ENST00000261837;ENST00000560116","GO:0016020(membrane);GO:0007165(signal transduction);GO:0005829(cytosol);GO:0004871(signal transducer activity);GO:0007186(G-protein coupled receptor signaling pathway);GO:0001750(photoreceptor outer segment);GO:0001917(photoreceptor inner segment);GO:0005634(nucleus);GO:0005886(plasma membrane);GO:0043209(myelin sheath);GO:0005096(GTPase activator activity);GO:0003924(GTPase activity);GO:0005515(protein binding);GO:0043547(positive regulation of GTPase activity);GO:0006457(protein folding);GO:0051087(chaperone binding);GO:0031682(G-protein gamma-subunit binding);GO:0007212(dopamine receptor signaling pathway);GO:1901386(negative regulation of voltage-gated calcium channel activity);GO:1902773(GTPase activator complex);GO:1902773(GTPase activator complex)","04014(Ras signaling pathway);04371(Apelin signaling pathway);04151(PI3K-Akt signaling pathway);04062(Chemokine signaling pathway);04926(Relaxin signaling pathway);04724(Glutamatergic synapse);04727(GABAergic synapse);04725(Cholinergic synapse);04728(Dopaminergic synapse);04726(Serotonergic synapse);04723(Retrograde endocannabinoid signaling);04713(Circadian entrainment);05200(Pathways in cancer);05032(Morphine addiction);05034(Alcoholism);05167(Kaposi's sarcoma-associated herpesvirus infection);05167(Kaposi's sarcoma-associated herpesvirus infection)","K04539","NA","G protein subunit beta 5 [Source:HGNC Symbol;Acc:HGNC:4401]",{"v":0.626217529243723,"d":"0.63"},{"v":0.754347739362502,"d":"0.75"},{"v":0.830144370516625,"d":"0.83"},{"v":-0.268565837324059,"d":"-0.27"},{"v":0.41383943975361,"d":"0.41"},{"v":0.880021883141801,"d":"0.88"},"down","no"]
["MSTRG.9072","PTPN4","MSTRG.9072.9;ENST00000263708;ENST00000420482;ENST00000431283;ENST00000488896;ENST00000488279;ENST00000469511;ENST00000430976;ENST00000441089;ENST00000433888","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0016787(hydrolase activity);GO:0004725(protein tyrosine phosphatase activity);GO:0016791(phosphatase activity);GO:0006470(protein dephosphorylation);GO:0016311(dephosphorylation);GO:0035335(peptidyl-tyrosine dephosphorylation);GO:0005886(plasma membrane);GO:0004721(phosphoprotein phosphatase activity);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0008092(cytoskeletal protein binding);GO:0004726(non-membrane spanning protein tyrosine phosphatase activity);GO:0009898(cytoplasmic side of plasma membrane);GO:0009898(cytoplasmic side of plasma membrane)","NA","NA","NA","protein tyrosine phosphatase, non-receptor type 4 [Source:HGNC Symbol;Acc:HGNC:9656]",{"v":5.11904365499641,"d":"5.12"},{"v":2.9278804985246,"d":"2.93"},{"v":1.74837861640049,"d":"1.75"},{"v":0.806017638417169,"d":"0.81"},{"v":0.413929929148504,"d":"0.41"},{"v":0.880021883141801,"d":"0.88"},"up","no"]
["MSTRG.372","HDAC1","ENST00000463172;ENST00000373548;ENST00000476391;ENST00000481281;ENST00000471488;ENST00000490081;ENST00000482310;ENST00000484305;ENST00000428704","GO:0008284(positive regulation of cell proliferation);GO:0043066(negative regulation of apoptotic process);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0005654(nucleoplasm);GO:0004407(histone deacetylase activity);GO:0016787(hydrolase activity);GO:0032041(NAD-dependent histone deacetylase activity (H3-K14 specific));GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0016569(covalent chromatin modification);GO:0070932(histone H3 deacetylation);GO:0000790(nuclear chromatin);GO:0005829(cytosol);GO:0006476(protein deacetylation);GO:0005515(protein binding);GO:0048511(rhythmic process);GO:0006325(chromatin organization);GO:0001047(core promoter binding);GO:0019213(deacetylase activity);GO:0043234(protein complex);GO:0016575(histone deacetylation);GO:0016032(viral process);GO:0000118(histone deacetylase complex);GO:0019899(enzyme binding);GO:0008134(transcription factor binding);GO:0045893(positive regulation of transcription, DNA-templated);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0045892(negative regulation of transcription, DNA-templated);GO:1904837(beta-catenin-TCF complex assembly);GO:1901796(regulation of signal transduction by p53 class mediator);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0000976(transcription regulatory region sequence-specific DNA binding);GO:0032922(circadian regulation of gene expression);GO:0042733(embryonic digit morphogenesis);GO:0006338(chromatin remodeling);GO:0045652(regulation of megakaryocyte differentiation);GO:0001103(RNA polymerase II repressing transcription factor binding);GO:0001106(RNA polymerase II transcription corepressor activity);GO:0090090(negative regulation of canonical Wnt signaling pathway);GO:0007596(blood coagulation);GO:0002039(p53 binding);GO:0033558(protein deacetylase activity);GO:0042826(histone deacetylase binding);GO:0051059(NF-kappaB binding);GO:0000785(chromatin);GO:0060766(negative regulation of androgen receptor signaling pathway);GO:0031492(nucleosomal DNA binding);GO:0016580(Sin3 complex);GO:0043044(ATP-dependent chromatin remodeling);GO:0016581(NuRD complex);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:0000980(RNA polymerase II distal enhancer sequence-specific DNA binding);GO:0001046(core promoter sequence-specific DNA binding);GO:0010870(positive regulation of receptor biosynthetic process);GO:0044212(transcription regulatory region DNA binding);GO:0043922(negative regulation by host of viral transcription);GO:0001085(RNA polymerase II transcription factor binding);GO:0010629(negative regulation of gene expression);GO:0042475(odontogenesis of dentin-containing tooth);GO:0047485(protein N-terminus binding);GO:0033613(activating transcription factor binding);GO:0070933(histone H4 deacetylation);GO:0070491(repressing transcription factor binding);GO:0006346(methylation-dependent chromatin silencing);GO:0009913(epidermal cell differentiation);GO:0060789(hair follicle placode formation);GO:0061029(eyelid development in camera-type eye);GO:0061198(fungiform papilla formation);GO:0061198(fungiform papilla formation)","04330(Notch signaling pathway);04110(Cell cycle);04919(Thyroid hormone signaling pathway);04213(Longevity regulating pathway - multiple species);05200(Pathways in cancer);05202(Transcriptional misregulation in cancers);05206(MicroRNAs in cancer);05203(Viral carcinogenesis);05220(Chronic myeloid leukemia);05016(Huntington's disease);05031(Amphetamine addiction);05034(Alcoholism);05169(Epstein-Barr virus infection);05165(Human papillomavirus infection);05165(Human papillomavirus infection)","K06067","EC:3.5.1.98","histone deacetylase 1 [Source:HGNC Symbol;Acc:HGNC:4852]",{"v":15.4118649434772,"d":"15.41"},{"v":18.5090191884936,"d":"18.51"},{"v":0.832667835422539,"d":"0.83"},{"v":-0.264186998766738,"d":"-0.26"},{"v":0.416315689521844,"d":"0.42"},{"v":0.881596298763161,"d":"0.88"},"down","no"]
["ENSG00000132970","WASF3","ENST00000335327;ENST00000361042","GO:0005737(cytoplasm);GO:0003779(actin binding);GO:0030036(actin cytoskeleton organization);GO:0005856(cytoskeleton);GO:0070062(extracellular exosome);GO:0007010(cytoskeleton organization);GO:0008360(regulation of cell shape);GO:0006461(protein complex assembly);GO:0014003(oligodendrocyte development);GO:0030032(lamellipodium assembly);GO:0031643(positive regulation of myelination);GO:0030027(lamellipodium);GO:0030041(actin filament polymerization);GO:0030041(actin filament polymerization)","04520(Adherens junction);04666(Fc gamma R-mediated phagocytosis);05231(Choline metabolism in cancer);05231(Choline metabolism in cancer)","K06083","NA","WAS protein family member 3 [Source:HGNC Symbol;Acc:HGNC:12734]",{"v":0.321187351995351,"d":"0.32"},{"v":0.393736817318869,"d":"0.39"},{"v":0.815741220702854,"d":"0.82"},{"v":-0.293816539283813,"d":"-0.29"},{"v":0.417012729074929,"d":"0.42"},{"v":0.881854957199264,"d":"0.88"},"down","no"]
["ENSG00000177034","MTX3","ENST00000509852;ENST00000617335;ENST00000512560","GO:0006810(transport);GO:0016020(membrane);GO:0015031(protein transport);GO:0005741(mitochondrial outer membrane);GO:0005739(mitochondrion);GO:0006626(protein targeting to mitochondrion);GO:0006626(protein targeting to mitochondrion)","NA","NA","NA","metaxin 3 [Source:HGNC Symbol;Acc:HGNC:24812]",{"v":0.246430133148055,"d":"0.25"},{"v":0.302135864325417,"d":"0.30"},{"v":0.815626882622038,"d":"0.82"},{"v":-0.294018768298972,"d":"-0.29"},{"v":0.41920741243251,"d":"0.42"},{"v":0.882621817798214,"d":"0.88"},"down","no"]
["MSTRG.5202","DENND4A","ENST00000564674;ENST00000443035;ENST00000635620;ENST00000562540;ENST00000561863;ENST00000431932;ENST00000568515;ENST00000567323","GO:0005634(nucleus);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0043547(positive regulation of GTPase activity);GO:0005085(guanyl-nucleotide exchange factor activity);GO:0005829(cytosol);GO:0017112(Rab guanyl-nucleotide exchange factor activity);GO:0061024(membrane organization);GO:0061024(membrane organization)","NA","NA","NA","DENN domain containing 4A [Source:HGNC Symbol;Acc:HGNC:24321]",{"v":5.37726761950485,"d":"5.38"},{"v":3.09085949063353,"d":"3.09"},{"v":1.73973214757901,"d":"1.74"},{"v":0.798865203139743,"d":"0.80"},{"v":0.420366841587544,"d":"0.42"},{"v":0.882829229693,"d":"0.88"},"up","no"]
["ENSG00000175395","ZNF25","ENST00000302609;ENST00000467975;ENST00000374633","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0005622(intracellular);GO:0005622(intracellular)","NA","NA","NA","zinc finger protein 25 [Source:HGNC Symbol;Acc:HGNC:13043]",{"v":2.02872759731385,"d":"2.03"},{"v":2.44197196489161,"d":"2.44"},{"v":0.830774319476636,"d":"0.83"},{"v":-0.267471473957959,"d":"-0.27"},{"v":0.421045576870932,"d":"0.42"},{"v":0.883359851789807,"d":"0.88"},"down","no"]
["MSTRG.2467","INTS5;C11orf98;LBHD1;AP001458.2","ENST00000330574;ENST00000532786;ENST00000524958;ENST00000431002;ENST00000526490;ENST00000377954;ENST00000525675;ENST00000528405;ENST00000415855;ENST00000354588;ENST00000527679","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005515(protein binding);GO:0005654(nucleoplasm);GO:0031965(nuclear membrane);GO:0042795(snRNA transcription from RNA polymerase II promoter);GO:0032039(integrator complex);GO:0016180(snRNA processing)","NA","NA","NA","integrator complex subunit 5 [Source:HGNC Symbol;Acc:HGNC:29352];chromosome 11 open reading frame 98 [Source:HGNC Symbol;Acc:HGNC:51238];LBH domain containing 1 [Source:HGNC Symbol;Acc:HGNC:28351]",{"v":2.87760071426521,"d":"2.88"},{"v":3.44644188074053,"d":"3.45"},{"v":0.834948278207119,"d":"0.83"},{"v":-0.260241263869797,"d":"-0.26"},{"v":0.421914635149031,"d":"0.42"},{"v":0.883961319964896,"d":"0.88"},"down","no"]
["MSTRG.11198","ANAPC13","ENST00000510994;ENST00000354910;ENST00000511751;ENST00000514612;ENST00000508755;ENST00000503439","GO:0005634(nucleus);GO:0016567(protein ubiquitination);GO:0051301(cell division);GO:0005515(protein binding);GO:0007049(cell cycle);GO:0070979(protein K11-linked ubiquitination);GO:0005680(anaphase-promoting complex);GO:0005680(anaphase-promoting complex)","04120(Ubiquitin mediated proteolysis);04110(Cell cycle);04114(Oocyte meiosis);04914(Progesterone-mediated oocyte maturation);04914(Progesterone-mediated oocyte maturation)","K12456","NA","anaphase promoting complex subunit 13 [Source:HGNC Symbol;Acc:HGNC:24540]",{"v":6.55754419245443,"d":"6.56"},{"v":7.8516766685036,"d":"7.85"},{"v":0.835177563890209,"d":"0.84"},{"v":-0.259845138845345,"d":"-0.26"},{"v":0.423428866853197,"d":"0.42"},{"v":0.884203516153899,"d":"0.88"},"down","no"]
["ENSG00000073464","CLCN4","ENST00000380833;ENST00000421085","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0055085(transmembrane transport);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0005216(ion channel activity);GO:1903959(regulation of anion transmembrane transport);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0006811(ion transport);GO:0015297(antiporter activity);GO:0006821(chloride transport);GO:1902476(chloride transmembrane transport);GO:0005247(voltage-gated chloride channel activity);GO:0005887(integral component of plasma membrane);GO:0005768(endosome);GO:0031902(late endosome membrane);GO:0034220(ion transmembrane transport);GO:0010008(endosome membrane);GO:0031901(early endosome membrane);GO:0005254(chloride channel activity);GO:0005254(chloride channel activity)","NA","NA","NA","chloride voltage-gated channel 4 [Source:HGNC Symbol;Acc:HGNC:2022]",{"v":1.31480832965091,"d":"1.31"},{"v":0.754489726027397,"d":"0.75"},{"v":1.7426457701071,"d":"1.74"},{"v":0.801279340750595,"d":"0.80"},{"v":0.424438066135735,"d":"0.42"},{"v":0.884203516153899,"d":"0.88"},"up","no"]
["MSTRG.3581","AC024909.3","ENST00000611513","NA","NA","NA","NA",null,{"v":7.08321,"d":"7.08"},{"v":4.081954,"d":"4.08"},{"v":1.73524983378059,"d":"1.74"},{"v":0.795143390762148,"d":"0.80"},{"v":0.425225702890991,"d":"0.43"},{"v":0.884203516153899,"d":"0.88"},"up","no"]
["ENSG00000037280","FLT4","ENST00000261937;ENST00000510000;ENST00000393347;ENST00000502603;ENST00000424276;ENST00000507059;ENST00000514810","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0004713(protein tyrosine kinase activity);GO:0007169(transmembrane receptor protein tyrosine kinase signaling pathway);GO:0005887(integral component of plasma membrane);GO:0042803(protein homodimerization activity);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0004714(transmembrane receptor protein tyrosine kinase activity);GO:0005021(vascular endothelial growth factor-activated receptor activity);GO:0048010(vascular endothelial growth factor receptor signaling pathway);GO:0002040(sprouting angiogenesis);GO:0001934(positive regulation of protein phosphorylation);GO:0008284(positive regulation of cell proliferation);GO:0043066(negative regulation of apoptotic process);GO:0070374(positive regulation of ERK1 and ERK2 cascade);GO:0019903(protein phosphatase binding);GO:0046777(protein autophosphorylation);GO:0001525(angiogenesis);GO:0019838(growth factor binding);GO:0010595(positive regulation of endothelial cell migration);GO:0035924(cellular response to vascular endothelial growth factor stimulus);GO:0043235(receptor complex);GO:0046330(positive regulation of JNK cascade);GO:0043410(positive regulation of MAPK cascade);GO:0048514(blood vessel morphogenesis);GO:0001938(positive regulation of endothelial cell proliferation);GO:0090037(positive regulation of protein kinase C signaling);GO:0018108(peptidyl-tyrosine phosphorylation);GO:0001944(vasculature development);GO:0060312(regulation of blood vessel remodeling);GO:0010575(positive regulation of vascular endothelial growth factor production);GO:0001946(lymphangiogenesis);GO:0036328(VEGF-C-activated receptor activity);GO:0001945(lymph vessel development);GO:0003016(respiratory system process);GO:0007585(respiratory gaseous exchange);GO:0038084(vascular endothelial growth factor signaling pathway);GO:0048286(lung alveolus development);GO:0048286(lung alveolus development)","04014(Ras signaling pathway);04015(Rap1 signaling pathway);04010(MAPK signaling pathway);04151(PI3K-Akt signaling pathway);04060(Cytokine-cytokine receptor interaction);04510(Focal adhesion);05200(Pathways in cancer);05224(Breast cancer);05224(Breast cancer)","K05097","EC:2.7.10.1","fms related tyrosine kinase 4 [Source:HGNC Symbol;Acc:HGNC:3767]",{"v":0.523578755535472,"d":"0.52"},{"v":0.299045533890646,"d":"0.30"},{"v":1.75083288729847,"d":"1.75"},{"v":0.808041388642257,"d":"0.81"},{"v":0.426812537404281,"d":"0.43"},{"v":0.884709737296536,"d":"0.88"},"up","no"]
["MSTRG.3471","PAN2;CNPY2;CS","ENST00000440411;ENST00000610546;ENST00000551359;ENST00000548013;ENST00000547226;ENST00000351328;ENST00000546937;ENST00000273308;ENST00000257931;ENST00000546891;ENST00000547100;ENST00000548849;ENST00000551968;ENST00000553164;ENST00000546466;ENST00000550655;ENST00000551936;ENST00000553230;ENST00000552331;ENST00000548041;ENST00000548567;ENST00000552630;ENST00000551720;ENST00000547994;ENST00000550028;ENST00000546585;ENST00000547570;ENST00000551473;ENST00000547518;ENST00000551475;ENST00000552222;ENST00000549221;ENST00000550996;ENST00000547912;ENST00000552868;ENST00000549964;ENST00000551430;ENST00000546388;ENST00000546621;ENST00000552688;ENST00000549348;ENST00000550555;ENST00000551441;ENST00000551137;ENST00000553191;ENST00000551276","GO:0003676(nucleic acid binding);GO:0006397(mRNA processing);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016787(hydrolase activity);GO:0090305(nucleic acid phosphodiester bond hydrolysis);GO:0005515(protein binding);GO:0004527(exonuclease activity);GO:0004518(nuclease activity);GO:0000289(nuclear-transcribed mRNA poly(A) tail shortening);GO:0000932(P-body);GO:0031251(PAN complex);GO:0005829(cytosol);GO:0004535(poly(A)-specific ribonuclease activity);GO:0090503(RNA phosphodiester bond hydrolysis, exonucleolytic);GO:0000175(3'-5'-exoribonuclease activity);GO:0010629(negative regulation of gene expression);GO:0005783(endoplasmic reticulum);GO:0005887(integral component of plasma membrane);GO:0007167(enzyme linked receptor protein signaling pathway);GO:0009888(tissue development);GO:0010988(regulation of low-density lipoprotein particle clearance);GO:0045716(positive regulation of low-density lipoprotein particle receptor biosynthetic process);GO:0016740(transferase activity);GO:0006099(tricarboxylic acid cycle);GO:0005739(mitochondrion);GO:0046912(transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer);GO:0006101(citrate metabolic process);GO:0004108(citrate (Si)-synthase activity);GO:0003723(RNA binding);GO:0005759(mitochondrial matrix);GO:0005975(carbohydrate metabolic process);GO:0070062(extracellular exosome);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0045716(positive regulation of low-density lipoprotein particle receptor biosynthetic process)","03018(RNA degradation);00020(Citrate cycle (TCA cycle));00630(Glyoxylate and dicarboxylate metabolism);00630(Glyoxylate and dicarboxylate metabolism)","K12571;K01647","EC:3.1.13.4;EC:2.3.3.1","PAN2 poly(A) specific ribonuclease subunit [Source:HGNC Symbol;Acc:HGNC:20074];canopy FGF signaling regulator 2 [Source:HGNC Symbol;Acc:HGNC:13529];citrate synthase [Source:HGNC Symbol;Acc:HGNC:2422]",{"v":4.41275280262521,"d":"4.41"},{"v":5.24613235766997,"d":"5.25"},{"v":0.841144008914236,"d":"0.84"},{"v":-0.249575275191206,"d":"-0.25"},{"v":0.428472429157783,"d":"0.43"},{"v":0.885139492397388,"d":"0.89"},"down","no"]
["MSTRG.11913","DDX60L","ENST00000511577;MSTRG.11913.1;MSTRG.11913.5;ENST00000510590;ENST00000515088;ENST00000260184;ENST00000513901;ENST00000512958;ENST00000505890;ENST00000514748;ENST00000512371;ENST00000503190;ENST00000513103;ENST00000505696;ENST00000505863;ENST00000505150","GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0016787(hydrolase activity);GO:0004386(helicase activity);GO:0004386(helicase activity)","NA","NA","NA","DEAD-box helicase 60 like [Source:HGNC Symbol;Acc:HGNC:26429]",{"v":11.3457776693673,"d":"11.35"},{"v":6.57269388544114,"d":"6.57"},{"v":1.72619900867417,"d":"1.73"},{"v":0.787598798396764,"d":"0.79"},{"v":0.42894826512252,"d":"0.43"},{"v":0.885283372289653,"d":"0.89"},"up","no"]
["MSTRG.2036","AL731571.1","ENST00000617058","NA","NA","NA","NA",null,{"v":0.290758,"d":"0.29"},{"v":0.163147,"d":"0.16"},{"v":1.78218416520071,"d":"1.78"},{"v":0.833646428045749,"d":"0.83"},{"v":0.430728000116567,"d":"0.43"},{"v":0.88532294824189,"d":"0.89"},"up","no"]
["ENSG00000079819","EPB41L2","ENST00000628542;ENST00000639623;ENST00000527411;ENST00000525198;ENST00000530481;ENST00000456097;ENST00000368126;ENST00000337057;ENST00000533912;ENST00000392427;ENST00000452150;ENST00000368128;ENST00000534166;ENST00000526782","GO:0003779(actin binding);GO:0005886(plasma membrane);GO:0005198(structural molecule activity);GO:0005911(cell-cell junction);GO:0005856(cytoskeleton);GO:0001558(regulation of cell growth);GO:0007010(cytoskeleton organization);GO:0007016(cytoskeletal anchoring at plasma membrane);GO:0006810(transport);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0051301(cell division);GO:0030054(cell junction);GO:0008092(cytoskeletal protein binding);GO:0007049(cell cycle);GO:0005925(focal adhesion);GO:0030866(cortical actin cytoskeleton organization);GO:0005515(protein binding);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0005200(structural constituent of cytoskeleton);GO:0031032(actomyosin structure organization);GO:0008180(COP9 signalosome);GO:0005938(cell cortex);GO:0099738(cell cortex region);GO:0008091(spectrin);GO:1904778(positive regulation of protein localization to cell cortex);GO:0030507(spectrin binding);GO:0042731(PH domain binding);GO:0042731(PH domain binding)","NA","NA","NA","erythrocyte membrane protein band 4.1 like 2 [Source:HGNC Symbol;Acc:HGNC:3379]",{"v":0.880434167926357,"d":"0.88"},{"v":0.508127490697674,"d":"0.51"},{"v":1.73270327633227,"d":"1.73"},{"v":0.793024615596679,"d":"0.79"},{"v":0.430810511617928,"d":"0.43"},{"v":0.88532294824189,"d":"0.89"},"up","no"]
["ENSG00000269404","SPIB","ENST00000595883;ENST00000596074;ENST00000594685;ENST00000270632;ENST00000599923;ENST00000597855;ENST00000439922","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0006355(regulation of transcription, DNA-templated);GO:0006366(transcription from RNA polymerase II promoter);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0043565(sequence-specific DNA binding);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0030154(cell differentiation);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0000980(RNA polymerase II distal enhancer sequence-specific DNA binding);GO:0001205(transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding);GO:0001205(transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding)","NA","NA","NA","Spi-B transcription factor [Source:HGNC Symbol;Acc:HGNC:11242]",{"v":2.86053840784863,"d":"2.86"},{"v":3.39872398364868,"d":"3.40"},{"v":0.841650696440997,"d":"0.84"},{"v":-0.248706487570348,"d":"-0.25"},{"v":0.432612750407409,"d":"0.43"},{"v":0.885607456278476,"d":"0.89"},"down","no"]
["MSTRG.8327","IRF3","ENST00000377139;ENST00000309877;ENST00000593922;ENST00000602190;ENST00000596788;ENST00000596822;MSTRG.8327.3;ENST00000597369;ENST00000600911;ENST00000377135;ENST00000600453;ENST00000596644;ENST00000599144;ENST00000593818;ENST00000601373;ENST00000594387;ENST00000597636;ENST00000595240;ENST00000601291;ENST00000601809;ENST00000597198;ENST00000597180;ENST00000599680;ENST00000598808;ENST00000598108","GO:0005737(cytoplasm);GO:0005634(nucleus);GO:0005829(cytosol);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0005515(protein binding);GO:0006974(cellular response to DNA damage stimulus);GO:0006915(apoptotic process);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0002376(immune system process);GO:0045087(innate immune response);GO:0000975(regulatory region DNA binding);GO:0042802(identical protein binding);GO:0051607(defense response to virus);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:0005654(nucleoplasm);GO:0001228(transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding);GO:0043565(sequence-specific DNA binding);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0016032(viral process);GO:0042803(protein homodimerization activity);GO:0035666(TRIF-dependent toll-like receptor signaling pathway);GO:0006366(transcription from RNA polymerase II promoter);GO:0019904(protein domain specific binding);GO:0032728(positive regulation of interferon-beta production);GO:0003712(transcription cofactor activity);GO:0060333(interferon-gamma-mediated signaling pathway);GO:0001077(transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0032481(positive regulation of type I interferon production);GO:0060337(type I interferon signaling pathway);GO:0032480(negative regulation of type I interferon production);GO:0032727(positive regulation of interferon-alpha production);GO:0032479(regulation of type I interferon production);GO:0039530(MDA-5 signaling pathway);GO:0071888(macrophage apoptotic process);GO:0001078(transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0009617(response to bacterium);GO:0031663(lipopolysaccharide-mediated signaling pathway);GO:0032496(response to lipopolysaccharide);GO:0043123(positive regulation of I-kappaB kinase/NF-kappaB signaling);GO:0043330(response to exogenous dsRNA);GO:0045351(type I interferon biosynthetic process);GO:0050715(positive regulation of cytokine secretion);GO:0060340(positive regulation of type I interferon-mediated signaling pathway);GO:0071222(cellular response to lipopolysaccharide);GO:0071359(cellular response to dsRNA);GO:0097300(programmed necrotic cell death);GO:0097300(programmed necrotic cell death)","04620(Toll-like receptor signaling pathway);04621(NOD-like receptor signaling pathway);04622(RIG-I-like receptor signaling pathway);04623(Cytosolic DNA-sensing pathway);05203(Viral carcinogenesis);05133(Pertussis);05162(Measles);05164(Influenza A);05161(Hepatitis B);05160(Hepatitis C);05168(Herpes simplex infection);05167(Kaposi's sarcoma-associated herpesvirus infection);05169(Epstein-Barr virus infection);05165(Human papillomavirus infection);05165(Human papillomavirus infection)","K05411","NA","interferon regulatory factor 3 [Source:HGNC Symbol;Acc:HGNC:6118]",{"v":5.98710204111755,"d":"5.99"},{"v":7.08935563152346,"d":"7.09"},{"v":0.844519918636238,"d":"0.84"},{"v":-0.243796644413888,"d":"-0.24"},{"v":0.432958264380199,"d":"0.43"},{"v":0.88566924859032,"d":"0.89"},"down","no"]
["ENSG00000121578","B4GALT4","ENST00000393765;ENST00000467604;ENST00000480814;ENST00000483209;ENST00000359213;ENST00000459820;ENST00000471675;ENST00000484595;ENST00000479308;ENST00000460321;ENST00000470111","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005794(Golgi apparatus);GO:0046872(metal ion binding);GO:0016740(transferase activity);GO:0016757(transferase activity, transferring glycosyl groups);GO:0005975(carbohydrate metabolic process);GO:0006486(protein glycosylation);GO:0032580(Golgi cisterna membrane);GO:0000139(Golgi membrane);GO:0003831(beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity);GO:0008378(galactosyltransferase activity);GO:0018146(keratan sulfate biosynthetic process);GO:0003945(N-acetyllactosamine synthase activity);GO:0006643(membrane lipid metabolic process);GO:0006643(membrane lipid metabolic process)","00533(Glycosaminoglycan biosynthesis - keratan sulfate);00601(Glycosphingolipid biosynthesis - lacto and neolacto series);00601(Glycosphingolipid biosynthesis - lacto and neolacto series)","K07969","EC:2.4.1.90;EC:2.4.1.275","beta-1,4-galactosyltransferase 4 [Source:HGNC Symbol;Acc:HGNC:927]",{"v":0.857696374807558,"d":"0.86"},{"v":1.02245629881036,"d":"1.02"},{"v":0.838858712891199,"d":"0.84"},{"v":-0.253500253681044,"d":"-0.25"},{"v":0.434560740498861,"d":"0.43"},{"v":0.886229584712362,"d":"0.89"},"down","no"]
["ENSG00000140386","SCAPER","ENST00000563290;ENST00000324767;ENST00000563688;ENST00000565507;ENST00000567601;ENST00000303521;ENST00000562948;ENST00000565372;ENST00000538941;ENST00000568549;ENST00000564590;ENST00000568382","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0005829(cytosol);GO:0005783(endoplasmic reticulum);GO:0005783(endoplasmic reticulum)","NA","NA","NA","S-phase cyclin A associated protein in the ER [Source:HGNC Symbol;Acc:HGNC:13081]",{"v":1.00728617149009,"d":"1.01"},{"v":0.582829354952627,"d":"0.58"},{"v":1.7282694547394,"d":"1.73"},{"v":0.789328165829136,"d":"0.79"},{"v":0.43660836027256,"d":"0.44"},{"v":0.887439664534573,"d":"0.89"},"up","no"]
["ENSG00000144559","TAMM41","ENST00000444133;ENST00000630288;ENST00000494388;ENST00000457498;ENST00000414736;ENST00000455809;ENST00000460246;ENST00000486090;ENST00000417723;ENST00000498127;ENST00000411947","GO:0016020(membrane);GO:0016740(transferase activity);GO:0005743(mitochondrial inner membrane);GO:0006629(lipid metabolic process);GO:0005739(mitochondrion);GO:0008654(phospholipid biosynthetic process);GO:0016779(nucleotidyltransferase activity);GO:0032049(cardiolipin biosynthetic process);GO:0004605(phosphatidate cytidylyltransferase activity);GO:0016024(CDP-diacylglycerol biosynthetic process);GO:0031314(extrinsic component of mitochondrial inner membrane);GO:0031314(extrinsic component of mitochondrial inner membrane)","NA","NA","NA","TAM41 mitochondrial translocator assembly and maintenance homolog [Source:HGNC Symbol;Acc:HGNC:25187]",{"v":0.433501933164557,"d":"0.43"},{"v":0.242470990886076,"d":"0.24"},{"v":1.78785070981228,"d":"1.79"},{"v":0.838226272759689,"d":"0.84"},{"v":0.437241150411287,"d":"0.44"},{"v":0.887439664534573,"d":"0.89"},"up","no"]
["MSTRG.5194","TRIP4","ENST00000261884;ENST00000560567;ENST00000560475;ENST00000559565;ENST00000558820;ENST00000560920;ENST00000557834;ENST00000559777;ENST00000561265;ENST00000558162;ENST00000559833","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0005654(nucleoplasm);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0005829(cytosol);GO:0005856(cytoskeleton);GO:0016604(nuclear body);GO:0003713(transcription coactivator activity);GO:0045893(positive regulation of transcription, DNA-templated);GO:0005813(centrosome);GO:0005815(microtubule organizing center);GO:0005515(protein binding);GO:0019901(protein kinase binding);GO:0030331(estrogen receptor binding);GO:0043234(protein complex);GO:0002020(protease binding);GO:0044389(ubiquitin-like protein ligase binding);GO:0030520(intracellular estrogen receptor signaling pathway);GO:0031594(neuromuscular junction);GO:0045661(regulation of myoblast differentiation);GO:0016922(ligand-dependent nuclear receptor binding);GO:0035035(histone acetyltransferase binding);GO:1901998(toxin transport);GO:0099053(activating signal cointegrator 1 complex);GO:0099053(activating signal cointegrator 1 complex)","NA","NA","NA","thyroid hormone receptor interactor 4 [Source:HGNC Symbol;Acc:HGNC:12310]",{"v":4.51871431100478,"d":"4.52"},{"v":5.34484871259968,"d":"5.34"},{"v":0.845433529363065,"d":"0.85"},{"v":-0.242236765004355,"d":"-0.24"},{"v":0.439621120193455,"d":"0.44"},{"v":0.889241202813727,"d":"0.89"},"down","no"]
["ENSG00000197122","SRC","ENST00000373578;ENST00000358208;ENST00000467556;ENST00000477475;ENST00000497734;ENST00000373567;ENST00000373558;ENST00000493775","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0005829(cytosol);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0005743(mitochondrial inner membrane);GO:0007155(cell adhesion);GO:0004713(protein tyrosine kinase activity);GO:0005886(plasma membrane);GO:0005739(mitochondrion);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0007049(cell cycle);GO:0004715(non-membrane spanning protein tyrosine kinase activity);GO:0007229(integrin-mediated signaling pathway);GO:0002376(immune system process);GO:0005764(lysosome);GO:0038096(Fc-gamma receptor signaling pathway involved in phagocytosis);GO:0050900(leukocyte migration);GO:0045087(innate immune response);GO:0020037(heme binding);GO:0045453(bone resorption);GO:0005654(nucleoplasm);GO:0045296(cadherin binding);GO:0070062(extracellular exosome);GO:0071902(positive regulation of protein serine/threonine kinase activity);GO:0042169(SH2 domain binding);GO:0002223(stimulatory C-type lectin receptor signaling pathway);GO:0016032(viral process);GO:0005770(late endosome);GO:0005102(receptor binding);GO:0051902(negative regulation of mitochondrial depolarization);GO:0043066(negative regulation of apoptotic process);GO:0044325(ion channel binding);GO:0007165(signal transduction);GO:0019899(enzyme binding);GO:0042127(regulation of cell proliferation);GO:0030168(platelet activation);GO:0007411(axon guidance);GO:0048013(ephrin receptor signaling pathway);GO:0046777(protein autophosphorylation);GO:0048010(vascular endothelial growth factor receptor signaling pathway);GO:0007179(transforming growth factor beta receptor signaling pathway);GO:0043154(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process);GO:2001243(negative regulation of intrinsic apoptotic signaling pathway);GO:0005070(SH3/SH2 adaptor activity);GO:0038128(ERBB2 signaling pathway);GO:0097110(scaffold protein binding);GO:0007417(central nervous system development);GO:0035556(intracellular signal transduction);GO:0051897(positive regulation of protein kinase B signaling);GO:0032463(negative regulation of protein homooligomerization);GO:0070851(growth factor receptor binding);GO:0007173(epidermal growth factor receptor signaling pathway);GO:0051219(phosphoprotein binding);GO:2001237(negative regulation of extrinsic apoptotic signaling pathway);GO:0010634(positive regulation of epithelial cell migration);GO:0050731(positive regulation of peptidyl-tyrosine phosphorylation);GO:0031295(T cell costimulation);GO:0019900(kinase binding);GO:0051895(negative regulation of focal adhesion assembly);GO:0070555(response to interleukin-1);GO:0016236(macroautophagy);GO:0033625(positive regulation of integrin activation);GO:0038083(peptidyl-tyrosine autophosphorylation);GO:0005901(caveola);GO:0031234(extrinsic component of cytoplasmic side of plasma membrane);GO:0035635(entry of bacterium into host cell);GO:2000641(regulation of early endosome to late endosome transport);GO:0051726(regulation of cell cycle);GO:0008022(protein C-terminus binding);GO:0005178(integrin binding);GO:0051974(negative regulation of telomerase activity);GO:0045124(regulation of bone resorption);GO:2000811(negative regulation of anoikis);GO:0018108(peptidyl-tyrosine phosphorylation);GO:0046875(ephrin receptor binding);GO:0007172(signal complex assembly);GO:0032211(negative regulation of telomere maintenance via telomerase);GO:0043114(regulation of vascular permeability);GO:2000394(positive regulation of lamellipodium morphogenesis);GO:0005080(protein kinase C binding);GO:0005158(insulin receptor binding);GO:0019901(protein kinase binding);GO:0019904(protein domain specific binding);GO:0030331(estrogen receptor binding);GO:0031625(ubiquitin protein ligase binding);GO:0032403(protein complex binding);GO:0050839(cell adhesion molecule binding);GO:0051427(hormone receptor binding);GO:0071253(connexin binding);GO:0008283(cell proliferation);GO:0009612(response to mechanical stimulus);GO:0009615(response to virus);GO:0010447(response to acidic pH);GO:0010628(positive regulation of gene expression);GO:0010632(regulation of epithelial cell migration);GO:0010641(positive regulation of platelet-derived growth factor receptor signaling pathway);GO:0010907(positive regulation of glucose metabolic process);GO:0010954(positive regulation of protein processing);GO:0014911(positive regulation of smooth muscle cell migration);GO:0016337(single organismal cell-cell adhesion);GO:0016477(cell migration);GO:0018105(peptidyl-serine phosphorylation);GO:0022407(regulation of cell-cell adhesion);GO:0030520(intracellular estrogen receptor signaling pathway);GO:0030900(forebrain development);GO:0031648(protein destabilization);GO:0031667(response to nutrient levels);GO:0031954(positive regulation of protein autophosphorylation);GO:0032148(activation of protein kinase B activity);GO:0032869(cellular response to insulin stimulus);GO:0033146(regulation of intracellular estrogen receptor signaling pathway);GO:0034332(adherens junction organization);GO:0034446(substrate adhesion-dependent cell spreading);GO:0034614(cellular response to reactive oxygen species);GO:0036035(osteoclast development);GO:0036120(cellular response to platelet-derived growth factor stimulus);GO:0042493(response to drug);GO:0042542(response to hydrogen peroxide);GO:0043065(positive regulation of apoptotic process);GO:0043149(stress fiber assembly);GO:0043393(regulation of protein binding);GO:0043406(positive regulation of MAP kinase activity);GO:0043552(positive regulation of phosphatidylinositol 3-kinase activity);GO:0045056(transcytosis);GO:0045737(positive regulation of cyclin-dependent protein serine/threonine kinase activity);GO:0045785(positive regulation of cell adhesion);GO:0045892(negative regulation of transcription, DNA-templated);GO:0045893(positive regulation of transcription, DNA-templated);GO:0046628(positive regulation of insulin receptor signaling pathway);GO:0048008(platelet-derived growth factor receptor signaling pathway);GO:0048011(neurotrophin TRK receptor signaling pathway);GO:0048477(oogenesis);GO:0050715(positive regulation of cytokine secretion);GO:0050847(progesterone receptor signaling pathway);GO:0051057(positive regulation of small GTPase mediated signal transduction);GO:0051222(positive regulation of protein transport);GO:0051385(response to mineralocorticoid);GO:0051602(response to electrical stimulus);GO:0060065(uterus development);GO:0060444(branching involved in mammary gland duct morphogenesis);GO:0060491(regulation of cell projection assembly);GO:0070374(positive regulation of ERK1 and ERK2 cascade);GO:0070542(response to fatty acid);GO:0071222(cellular response to lipopolysaccharide);GO:0071375(cellular response to peptide hormone stimulus);GO:0071393(cellular response to progesterone stimulus);GO:0071398(cellular response to fatty acid);GO:0071456(cellular response to hypoxia);GO:0071498(cellular response to fluid shear stress);GO:0071560(cellular response to transforming growth factor beta stimulus);GO:0071801(regulation of podosome assembly);GO:0071803(positive regulation of podosome assembly);GO:0086098(angiotensin-activated signaling pathway involved in heart process);GO:0090263(positive regulation of canonical Wnt signaling pathway);GO:1900182(positive regulation of protein localization to nucleus);GO:1902533(positive regulation of intracellular signal transduction);GO:2000573(positive regulation of DNA biosynthetic process);GO:2001286(regulation of caveolin-mediated endocytosis);GO:0002102(podosome);GO:0005884(actin filament);GO:0014069(postsynaptic density);GO:0032587(ruffle membrane);GO:0043005(neuron projection);GO:0048471(perinuclear region of cytoplasm);GO:0048471(perinuclear region of cytoplasm)","04015(Rap1 signaling pathway);04012(ErbB signaling pathway);04370(VEGF signaling pathway);04144(Endocytosis);04137(Mitophagy - animal);04510(Focal adhesion);04520(Adherens junction);04530(Tight junction);04540(Gap junction);04810(Regulation of actin cytoskeleton);04611(Platelet activation);04062(Chemokine signaling pathway);04912(GnRH signaling pathway);04915(Estrogen signaling pathway);04917(Prolactin signaling pathway);04921(Oxytocin signaling pathway);04926(Relaxin signaling pathway);04919(Thyroid hormone signaling pathway);04727(GABAergic synapse);04750(Inflammatory mediator regulation of TRP channels);04360(Axon guidance);05205(Proteoglycans in cancer);05203(Viral carcinogenesis);05219(Bladder cancer);05418(Fluid shear stress and atherosclerosis);05120(Epithelial cell signaling in Helicobacter pylori infection);05131(Shigellosis);05152(Tuberculosis);05100(Bacterial invasion of epithelial cells);05161(Hepatitis B);05167(Kaposi's sarcoma-associated herpesvirus infection);01521(EGFR tyrosine kinase inhibitor resistance);01522(Endocrine resistance);01522(Endocrine resistance)","K05704","EC:2.7.10.2","SRC proto-oncogene, non-receptor tyrosine kinase [Source:HGNC Symbol;Acc:HGNC:11283]",{"v":3.0732477755102,"d":"3.07"},{"v":1.78975286332715,"d":"1.79"},{"v":1.71713527520053,"d":"1.72"},{"v":0.780003698730502,"d":"0.78"},{"v":0.44028023748751,"d":"0.44"},{"v":0.889241202813727,"d":"0.89"},"up","no"]
["MSTRG.3259","LRMP","ENST00000549437;ENST00000354454;ENST00000557489;ENST00000547044;ENST00000553398;ENST00000548766;ENST00000555141;ENST00000555877;ENST00000361433;ENST00000556887;ENST00000555885;ENST00000557472;ENST00000555194;ENST00000554272;ENST00000536173;ENST00000555165;ENST00000550945;MSTRG.3259.5;ENST00000554942","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005694(chromosome);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005856(cytoskeleton);GO:0002376(immune system process);GO:0000922(spindle pole);GO:0005815(microtubule organizing center);GO:0005886(plasma membrane);GO:0007338(single fertilization);GO:0005887(integral component of plasma membrane);GO:0043312(neutrophil degranulation);GO:0006903(vesicle targeting);GO:0035577(azurophil granule membrane);GO:0005635(nuclear envelope);GO:0006906(vesicle fusion);GO:0006906(vesicle fusion)","NA","NA","NA","lymphoid restricted membrane protein [Source:HGNC Symbol;Acc:HGNC:6690]",{"v":12.1608558213313,"d":"12.16"},{"v":14.3259348909228,"d":"14.33"},{"v":0.848869963037223,"d":"0.85"},{"v":-0.236384528211455,"d":"-0.24"},{"v":0.441262540871767,"d":"0.44"},{"v":0.889241202813727,"d":"0.89"},"down","no"]
["MSTRG.7627","MKNK2","MSTRG.7627.8;MSTRG.7627.1;ENST00000591601;ENST00000588014;ENST00000586828;ENST00000591142;ENST00000585667;ENST00000586620;ENST00000589441;ENST00000591588;ENST00000587416","GO:0004672(protein kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0004674(protein serine/threonine kinase activity);GO:0005730(nucleolus);GO:0016740(transferase activity);GO:0005515(protein binding);GO:0016604(nuclear body);GO:0006915(apoptotic process);GO:0006417(regulation of translation);GO:0005516(calmodulin binding);GO:0018105(peptidyl-serine phosphorylation);GO:0007166(cell surface receptor signaling pathway);GO:0016605(PML body);GO:0030097(hemopoiesis);GO:0035556(intracellular signal transduction);GO:0071243(cellular response to arsenic-containing substance);GO:0004683(calmodulin-dependent protein kinase activity);GO:0009931(calcium-dependent protein serine/threonine kinase activity);GO:0046777(protein autophosphorylation);GO:0097192(extrinsic apoptotic signaling pathway in absence of ligand);GO:0097192(extrinsic apoptotic signaling pathway in absence of ligand)","04010(MAPK signaling pathway);04066(HIF-1 signaling pathway);04910(Insulin signaling pathway);04910(Insulin signaling pathway)","NA","NA","MAP kinase interacting serine/threonine kinase 2 [Source:HGNC Symbol;Acc:HGNC:7111]",{"v":21.9332373373151,"d":"21.93"},{"v":12.8231337117937,"d":"12.82"},{"v":1.71044284730047,"d":"1.71"},{"v":0.774369898730939,"d":"0.77"},{"v":0.441899731233896,"d":"0.44"},{"v":0.88939022163245,"d":"0.89"},"up","no"]
["MSTRG.8784","GMCL1","ENST00000282570;ENST00000471404;ENST00000495047;ENST00000468386","GO:0005634(nucleus);GO:0005515(protein binding);GO:0007275(multicellular organism development);GO:0030154(cell differentiation);GO:0007283(spermatogenesis);GO:0042802(identical protein binding);GO:0000151(ubiquitin ligase complex);GO:0016363(nuclear matrix);GO:0006355(regulation of transcription, DNA-templated);GO:0005635(nuclear envelope);GO:0005635(nuclear envelope)","NA","NA","NA","germ cell-less, spermatogenesis associated 1 [Source:HGNC Symbol;Acc:HGNC:23843]",{"v":6.56855676493295,"d":"6.57"},{"v":3.84417896383584,"d":"3.84"},{"v":1.70870212514212,"d":"1.71"},{"v":0.772900916594978,"d":"0.77"},{"v":0.444022495996117,"d":"0.44"},{"v":0.889934292416752,"d":"0.89"},"up","no"]
["ENSG00000152620","NADK2","ENST00000381937;ENST00000404560;ENST00000511613;ENST00000506945;ENST00000397338","GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0008152(metabolic process);GO:0003951(NAD+ kinase activity);GO:0005739(mitochondrion);GO:0042803(protein homodimerization activity);GO:0006741(NADP biosynthetic process);GO:0019674(NAD metabolic process);GO:0005759(mitochondrial matrix);GO:0005759(mitochondrial matrix)","00760(Nicotinate and nicotinamide metabolism);00760(Nicotinate and nicotinamide metabolism)","K00858","EC:2.7.1.23","NAD kinase 2, mitochondrial [Source:HGNC Symbol;Acc:HGNC:26404]",{"v":0.833261207778915,"d":"0.83"},{"v":0.480247255271238,"d":"0.48"},{"v":1.73506709019773,"d":"1.74"},{"v":0.794991448869372,"d":"0.79"},{"v":0.444872376260623,"d":"0.44"},{"v":0.889934292416752,"d":"0.89"},"up","no"]
["ENSG00000165861","ZFYVE1","ENST00000556143;ENST00000553891;ENST00000556761;ENST00000555072;ENST00000554145;ENST00000554250","GO:0046872(metal ion binding);GO:0005794(Golgi apparatus);GO:0005783(endoplasmic reticulum);GO:0008270(zinc ion binding);GO:0005515(protein binding);GO:0048471(perinuclear region of cytoplasm);GO:0016236(macroautophagy);GO:0010923(negative regulation of phosphatase activity);GO:0005547(phosphatidylinositol-3,4,5-trisphosphate binding);GO:0043325(phosphatidylinositol-3,4-bisphosphate binding);GO:0005795(Golgi stack);GO:0016020(membrane);GO:0044233(ER-mitochondrion membrane contact site);GO:0005776(autophagosome);GO:0097629(extrinsic component of omegasome membrane);GO:0005545(1-phosphatidylinositol binding);GO:0009267(cellular response to starvation);GO:0000407(pre-autophagosomal structure);GO:1990462(omegasome);GO:1990462(omegasome)","04140(Autophagy - animal);04140(Autophagy - animal)","K17603","NA","zinc finger FYVE-type containing 1 [Source:HGNC Symbol;Acc:HGNC:13180]",{"v":4.05722351583113,"d":"4.06"},{"v":2.37323522785526,"d":"2.37"},{"v":1.70957495835662,"d":"1.71"},{"v":0.773637680845909,"d":"0.77"},{"v":0.445940520027217,"d":"0.45"},{"v":0.889934292416752,"d":"0.89"},"up","no"]
["ENSG00000103227","LMF1","ENST00000262301;ENST00000562380;ENST00000570168;ENST00000568897;ENST00000611669;ENST00000566627;ENST00000569516;ENST00000568964;ENST00000545827;ENST00000562226;ENST00000565276;ENST00000568268;ENST00000567595","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0051004(regulation of lipoprotein lipase activity);GO:0006641(triglyceride metabolic process);GO:0051604(protein maturation);GO:0006888(ER to Golgi vesicle-mediated transport);GO:0009306(protein secretion);GO:0033578(protein glycosylation in Golgi);GO:0034382(chylomicron remnant clearance);GO:0051006(positive regulation of lipoprotein lipase activity);GO:0090181(regulation of cholesterol metabolic process);GO:0090207(regulation of triglyceride metabolic process);GO:0005794(Golgi apparatus);GO:0005794(Golgi apparatus)","NA","NA","NA","lipase maturation factor 1 [Source:HGNC Symbol;Acc:HGNC:14154]",{"v":0.492813157050893,"d":"0.49"},{"v":0.284692227377627,"d":"0.28"},{"v":1.73103832721505,"d":"1.73"},{"v":0.791637668015315,"d":"0.79"},{"v":0.446712852846852,"d":"0.45"},{"v":0.890002514876514,"d":"0.89"},"up","no"]
["MSTRG.408","KIAA0319L","ENST00000325722;ENST00000485551;ENST00000467109;ENST00000492544;ENST00000478463;ENST00000461312;ENST00000470388;ENST00000473844;ENST00000474856;ENST00000473423;ENST00000476329;ENST00000482929;ENST00000373266;ENST00000469892;ENST00000473465","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005794(Golgi apparatus);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0000139(Golgi membrane);GO:0031410(cytoplasmic vesicle);GO:0070062(extracellular exosome);GO:0070062(extracellular exosome)","NA","NA","NA","KIAA0319 like [Source:HGNC Symbol;Acc:HGNC:30071]",{"v":4.78920390757088,"d":"4.79"},{"v":2.80843563734552,"d":"2.81"},{"v":1.70529238551379,"d":"1.71"},{"v":0.77001912163437,"d":"0.77"},{"v":0.447185453741881,"d":"0.45"},{"v":0.890002514876514,"d":"0.89"},"up","no"]
["MSTRG.329","TAF12","ENST00000373824;ENST00000263974;ENST00000495422;ENST00000471683","GO:0005634(nucleus);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0046982(protein heterodimerization activity);GO:0005515(protein binding);GO:0004402(histone acetyltransferase activity);GO:0006352(DNA-templated transcription, initiation);GO:0003713(transcription coactivator activity);GO:0005669(transcription factor TFIID complex);GO:0006367(transcription initiation from RNA polymerase II promoter);GO:0005654(nucleoplasm);GO:0008134(transcription factor binding);GO:0006366(transcription from RNA polymerase II promoter);GO:0006368(transcription elongation from RNA polymerase II promoter);GO:1901796(regulation of signal transduction by p53 class mediator);GO:0033276(transcription factor TFTC complex);GO:0051091(positive regulation of sequence-specific DNA binding transcription factor activity);GO:0043966(histone H3 acetylation);GO:0000124(SAGA complex);GO:0030914(STAGA complex);GO:0051123(RNA polymerase II transcriptional preinitiation complex assembly);GO:0017025(TBP-class protein binding);GO:0001102(RNA polymerase II activating transcription factor binding);GO:0001102(RNA polymerase II activating transcription factor binding)","03022(Basal transcription factors);03022(Basal transcription factors)","K03126","NA","TATA-box binding protein associated factor 12 [Source:HGNC Symbol;Acc:HGNC:11545]",{"v":7.98423786563971,"d":"7.98"},{"v":9.36063527471117,"d":"9.36"},{"v":0.852958974612551,"d":"0.85"},{"v":-0.229451742026545,"d":"-0.23"},{"v":0.449165805470935,"d":"0.45"},{"v":0.890772256667113,"d":"0.89"},"down","no"]
["MSTRG.7772","ZNF414","ENST00000255616;ENST00000600906;ENST00000602128;ENST00000593661;ENST00000596772;ENST00000393927;ENST00000595348","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0005515(protein binding)","NA","NA","NA","zinc finger protein 414 [Source:HGNC Symbol;Acc:HGNC:20630]",{"v":1.48263437781001,"d":"1.48"},{"v":0.864307754894851,"d":"0.86"},{"v":1.7154009893043,"d":"1.72"},{"v":0.778545857832654,"d":"0.78"},{"v":0.450361944629398,"d":"0.45"},{"v":0.890834708450461,"d":"0.89"},"up","no"]
["MSTRG.14660","PUM3","ENST00000397885;ENST00000469168;ENST00000382032","GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005730(nucleolus);GO:0003677(DNA binding);GO:0005694(chromosome);GO:0005783(endoplasmic reticulum);GO:0005654(nucleoplasm);GO:0005515(protein binding);GO:0003729(mRNA binding);GO:0006417(regulation of translation);GO:0010835(regulation of protein ADP-ribosylation);GO:0010835(regulation of protein ADP-ribosylation)","NA","NA","NA","pumilio RNA binding family member 3 [Source:HGNC Symbol;Acc:HGNC:29676]",{"v":2.93300763021795,"d":"2.93"},{"v":3.43545290986332,"d":"3.44"},{"v":0.853747004302452,"d":"0.85"},{"v":-0.228119483722502,"d":"-0.23"},{"v":0.451170479443762,"d":"0.45"},{"v":0.890834708450461,"d":"0.89"},"down","no"]
["ENSG00000198087","CD2AP","ENST00000359314;ENST00000477159;ENST00000463175;ENST00000486693","GO:0005737(cytoplasm);GO:0051301(cell division);GO:0005856(cytoskeleton);GO:0042995(cell projection);GO:0005515(protein binding);GO:0007010(cytoskeleton organization);GO:0007049(cell cycle);GO:0045296(cadherin binding);GO:0070062(extracellular exosome);GO:0031941(filamentous actin);GO:0017124(SH3 domain binding);GO:0001726(ruffle);GO:0007165(signal transduction);GO:0005200(structural constituent of cytoskeleton);GO:0006461(protein complex assembly);GO:0015629(actin cytoskeleton);GO:0006930(substrate-dependent cell migration, cell extension);GO:0005172(vascular endothelial growth factor receptor binding);GO:0008013(beta-catenin binding);GO:0008022(protein C-terminus binding);GO:0032403(protein complex binding);GO:0016050(vesicle organization);GO:0016337(single organismal cell-cell adhesion);GO:0016477(cell migration);GO:0032911(negative regulation of transforming growth factor beta1 production);GO:0043161(proteasome-mediated ubiquitin-dependent protein catabolic process);GO:0048259(regulation of receptor-mediated endocytosis);GO:1900182(positive regulation of protein localization to nucleus);GO:2000249(regulation of actin cytoskeleton reorganization);GO:0005886(plasma membrane);GO:0005911(cell-cell junction);GO:0030139(endocytic vesicle);GO:0031252(cell leading edge);GO:0043234(protein complex);GO:0048471(perinuclear region of cytoplasm);GO:0048471(perinuclear region of cytoplasm)","05100(Bacterial invasion of epithelial cells);05100(Bacterial invasion of epithelial cells)","K13738","NA","CD2 associated protein [Source:HGNC Symbol;Acc:HGNC:14258]",{"v":3.18898682298919,"d":"3.19"},{"v":1.87851154969634,"d":"1.88"},{"v":1.6976136364478,"d":"1.70"},{"v":0.763508150171039,"d":"0.76"},{"v":0.453271497136406,"d":"0.45"},{"v":0.891755042319172,"d":"0.89"},"up","no"]
["MSTRG.7572","CDC34","ENST00000606065;ENST00000215574;ENST00000586283;ENST00000607527;ENST00000606400;ENST00000593036;ENST00000586788","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016607(nuclear speck);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0005829(cytosol);GO:0016740(transferase activity);GO:0016567(protein ubiquitination);GO:0051301(cell division);GO:0005515(protein binding);GO:0007049(cell cycle);GO:0043525(positive regulation of neuron apoptotic process);GO:0070848(response to growth factor);GO:0090261(positive regulation of inclusion body assembly);GO:0031625(ubiquitin protein ligase binding);GO:0061630(ubiquitin protein ligase activity);GO:0005654(nucleoplasm);GO:0061631(ubiquitin conjugating enzyme activity);GO:0035458(cellular response to interferon-beta);GO:0004842(ubiquitin-protein transferase activity);GO:0043161(proteasome-mediated ubiquitin-dependent protein catabolic process);GO:0006464(cellular protein modification process);GO:0070936(protein K48-linked ubiquitination);GO:0006270(DNA replication initiation);GO:0000209(protein polyubiquitination);GO:0043951(negative regulation of cAMP-mediated signaling);GO:0000082(G1/S transition of mitotic cell cycle);GO:0000082(G1/S transition of mitotic cell cycle)","04120(Ubiquitin mediated proteolysis);05168(Herpes simplex infection);05168(Herpes simplex infection)","K02207","EC:2.3.2.23","cell division cycle 34 [Source:HGNC Symbol;Acc:HGNC:1734]",{"v":35.2653488697219,"d":"35.27"},{"v":41.1394160514933,"d":"41.14"},{"v":0.857215591625828,"d":"0.86"},{"v":-0.222270003906159,"d":"-0.22"},{"v":0.453589321638593,"d":"0.45"},{"v":0.891755042319172,"d":"0.89"},"down","no"]
["ENSG00000229419","RALGAPA1P1","ENST00000443361","NA","NA","NA","NA","Ral GTPase activating protein catalytic alpha subunit 1 pseudogene 1 [Source:HGNC Symbol;Acc:HGNC:23203]",{"v":0.311746,"d":"0.31"},{"v":0.178688,"d":"0.18"},{"v":1.74463869985673,"d":"1.74"},{"v":0.802928297240611,"d":"0.80"},{"v":0.454398684336771,"d":"0.45"},{"v":0.891755042319172,"d":"0.89"},"up","no"]
["ENSG00000126767","ELK1","ENST00000376983;ENST00000247161;ENST00000468956;ENST00000343894","GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0006355(regulation of transcription, DNA-templated);GO:0006366(transcription from RNA polymerase II promoter);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0043565(sequence-specific DNA binding);GO:0005515(protein binding);GO:0001047(core promoter binding);GO:0003682(chromatin binding);GO:0003690(double-stranded DNA binding);GO:0009416(response to light stimulus);GO:0045893(positive regulation of transcription, DNA-templated);GO:0071394(cellular response to testosterone stimulus);GO:0071396(cellular response to lipid);GO:0071480(cellular response to gamma radiation);GO:0071774(response to fibroblast growth factor);GO:1901216(positive regulation of neuron death);GO:0005737(cytoplasm);GO:0005739(mitochondrion);GO:0030425(dendrite);GO:0043025(neuronal cell body);GO:0043679(axon terminus);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:0030154(cell differentiation);GO:0001077(transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0001085(RNA polymerase II transcription factor binding);GO:0001085(RNA polymerase II transcription factor binding)","04014(Ras signaling pathway);04010(MAPK signaling pathway);04012(ErbB signaling pathway);04510(Focal adhesion);04910(Insulin signaling pathway);04912(GnRH signaling pathway);04921(Oxytocin signaling pathway);05200(Pathways in cancer);05205(Proteoglycans in cancer);05225(Hepatocellular carcinoma);05213(Endometrial cancer);05020(Prion diseases);05166(HTLV-I infection);05161(Hepatitis B);05140(Leishmaniasis);05140(Leishmaniasis)","K04375","NA","ELK1, ETS transcription factor [Source:HGNC Symbol;Acc:HGNC:3321]",{"v":3.69795336521483,"d":"3.70"},{"v":2.17740461830489,"d":"2.18"},{"v":1.69833081739933,"d":"1.70"},{"v":0.764117508440379,"d":"0.76"},{"v":0.456409689079142,"d":"0.46"},{"v":0.892454237965326,"d":"0.89"},"up","no"]
["MSTRG.13923","ZNF277","ENST00000361822;ENST00000421864;ENST00000450657;ENST00000425229","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0000979(RNA polymerase II core promoter sequence-specific DNA binding);GO:0070301(cellular response to hydrogen peroxide);GO:2000772(regulation of cellular senescence);GO:2000772(regulation of cellular senescence)","NA","NA","NA","zinc finger protein 277 [Source:HGNC Symbol;Acc:HGNC:13070]",{"v":2.33902959616343,"d":"2.34"},{"v":2.72442405480817,"d":"2.72"},{"v":0.858540942639021,"d":"0.86"},{"v":-0.22004115887332,"d":"-0.22"},{"v":0.457643277497284,"d":"0.46"},{"v":0.893440714772927,"d":"0.89"},"down","no"]
["MSTRG.10462","SUN2;DNAL4","ENST00000405018;MSTRG.10462.2;ENST00000469086;ENST00000456894;ENST00000405510;MSTRG.10462.1;ENST00000216068;ENST00000406622;ENST00000470642;ENST00000475512;ENST00000494273;ENST00000420859;ENST00000417332;ENST00000438058;ENST00000452294;ENST00000477262;ENST00000464202;ENST00000406199;ENST00000433561;ENST00000480307;ENST00000430185;ENST00000439339;ENST00000455125","GO:0005634(nucleus);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0031965(nuclear membrane);GO:0005515(protein binding);GO:0005639(integral component of nuclear inner membrane);GO:0034993(LINC complex);GO:0051321(meiotic cell cycle);GO:0008017(microtubule binding);GO:0042802(identical protein binding);GO:0005768(endosome);GO:0005637(nuclear inner membrane);GO:0030335(positive regulation of cell migration);GO:0010008(endosome membrane);GO:0007052(mitotic spindle organization);GO:0005635(nuclear envelope);GO:0005521(lamin binding);GO:0006998(nuclear envelope organization);GO:0043495(protein anchor);GO:0090286(cytoskeletal anchoring at nuclear membrane);GO:0090292(nuclear matrix anchoring at nuclear membrane);GO:0051642(centrosome localization);GO:0007097(nuclear migration);GO:0031022(nuclear migration along microfilament);GO:0021817(nucleokinesis involved in cell motility in cerebral cortex radial glia guided migration);GO:0000784(nuclear chromosome, telomeric region);GO:0000794(condensed nuclear chromosome);GO:0005737(cytoplasm);GO:0005856(cytoskeleton);GO:0042995(cell projection);GO:0005874(microtubule);GO:0003774(motor activity);GO:0030286(dynein complex);GO:0005886(plasma membrane);GO:0007017(microtubule-based process);GO:0005929(cilium);GO:0051959(dynein light intermediate chain binding);GO:0007018(microtubule-based movement);GO:0008574(ATP-dependent microtubule motor activity, plus-end-directed);GO:2000582(positive regulation of ATP-dependent microtubule motor activity, plus-end-directed);GO:0003777(microtubule motor activity);GO:0008092(cytoskeletal protein binding);GO:0045505(dynein intermediate chain binding);GO:0000794(condensed nuclear chromosome)","05016(Huntington's disease);05016(Huntington's disease)","K10412","NA","Sad1 and UNC84 domain containing 2 [Source:HGNC Symbol;Acc:HGNC:14210];dynein axonemal light chain 4 [Source:HGNC Symbol;Acc:HGNC:2955]",{"v":43.9465129858266,"d":"43.95"},{"v":26.03642029742,"d":"26.04"},{"v":1.68788614117515,"d":"1.69"},{"v":0.755217588226279,"d":"0.76"},{"v":0.458366866858283,"d":"0.46"},{"v":0.893440714772927,"d":"0.89"},"up","no"]
["MSTRG.12932","HLA-DPB1","ENST00000418931;ENST00000469120;ENST00000471184;ENST00000416804;ENST00000428835;ENST00000498038","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005794(Golgi apparatus);GO:0005765(lysosomal membrane);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005886(plasma membrane);GO:0006955(immune response);GO:0002376(immune system process);GO:0005764(lysosome);GO:0002504(antigen processing and presentation of peptide or polysaccharide antigen via MHC class II);GO:0019882(antigen processing and presentation);GO:0042613(MHC class II protein complex);GO:0005768(endosome);GO:0050852(T cell receptor signaling pathway);GO:0042102(positive regulation of T cell proliferation);GO:0050870(positive regulation of T cell activation);GO:0010008(endosome membrane);GO:0019886(antigen processing and presentation of exogenous peptide antigen via MHC class II);GO:0032588(trans-Golgi network membrane);GO:0009986(cell surface);GO:0000139(Golgi membrane);GO:0030666(endocytic vesicle membrane);GO:0060333(interferon-gamma-mediated signaling pathway);GO:0012507(ER to Golgi transport vesicle membrane);GO:0031295(T cell costimulation);GO:0042605(peptide antigen binding);GO:0071556(integral component of lumenal side of endoplasmic reticulum membrane);GO:0030669(clathrin-coated endocytic vesicle membrane);GO:0030658(transport vesicle membrane);GO:0032729(positive regulation of interferon-gamma production);GO:0032729(positive regulation of interferon-gamma production)","04514(Cell adhesion molecules (CAMs));04145(Phagosome);04640(Hematopoietic cell lineage);04612(Antigen processing and presentation);04658(Th1 and Th2 cell differentiation);04659(Th17 cell differentiation);04672(Intestinal immune network for IgA production);05310(Asthma);05322(Systemic lupus erythematosus);05323(Rheumatoid arthritis);05320(Autoimmune thyroid disease);05321(Inflammatiory bowel disease (IBD));05330(Allograft rejection);05332(Graft-versus-host disease);05416(Viral myocarditis);04940(Type I diabetes mellitus);05150(Staphylococcus aureus infection);05152(Tuberculosis);05166(HTLV-I infection);05164(Influenza A);05168(Herpes simplex infection);05169(Epstein-Barr virus infection);05145(Toxoplasmosis);05140(Leishmaniasis);05140(Leishmaniasis)","K06752","NA","major histocompatibility complex, class II, DP beta 1 [Source:HGNC Symbol;Acc:HGNC:4940]",{"v":34.1076597047653,"d":"34.11"},{"v":39.6035943468291,"d":"39.60"},{"v":0.86122636763893,"d":"0.86"},{"v":-0.215535604597743,"d":"-0.22"},{"v":0.459465823700763,"d":"0.46"},{"v":0.893440714772927,"d":"0.89"},"down","no"]
["MSTRG.8238","SYMPK","ENST00000599460;ENST00000245934;ENST00000599814;ENST00000593504;ENST00000600237;ENST00000598896;ENST00000598364;ENST00000598155;ENST00000594293;ENST00000593959;ENST00000602061;ENST00000598329;ENST00000596824;ENST00000598059","GO:0006397(mRNA processing);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0007155(cell adhesion);GO:0005886(plasma membrane);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0030054(cell junction);GO:0005923(bicellular tight junction);GO:0006369(termination of RNA polymerase II transcription);GO:0031124(mRNA 3'-end processing);GO:0000398(mRNA splicing, via spliceosome);GO:0006406(mRNA export from nucleus);GO:0006378(mRNA polyadenylation);GO:0097165(nuclear stress granule);GO:0035307(positive regulation of protein dephosphorylation);GO:0035307(positive regulation of protein dephosphorylation)","03015(mRNA surveillance pathway);04530(Tight junction);04530(Tight junction)","K06100","NA","symplekin [Source:HGNC Symbol;Acc:HGNC:22935]",{"v":3.59931320841174,"d":"3.60"},{"v":2.13078677785096,"d":"2.13"},{"v":1.68919445428598,"d":"1.69"},{"v":0.756335415816117,"d":"0.76"},{"v":0.461121446125794,"d":"0.46"},{"v":0.893440714772927,"d":"0.89"},"up","no"]
["ENSG00000046647","GEMIN8","ENST00000398355;ENST00000380523;ENST00000477386;ENST00000460203;ENST00000332885","GO:0006397(mRNA processing);GO:0008380(RNA splicing);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0000387(spliceosomal snRNP assembly);GO:0032797(SMN complex);GO:0005515(protein binding);GO:0005654(nucleoplasm);GO:0051170(nuclear import);GO:0034719(SMN-Sm protein complex);GO:0097504(Gemini of coiled bodies);GO:0097504(Gemini of coiled bodies)","03013(RNA transport);03013(RNA transport)","K13136","NA","gem nuclear organelle associated protein 8 [Source:HGNC Symbol;Acc:HGNC:26044]",{"v":1.43944179579208,"d":"1.44"},{"v":1.69300421534653,"d":"1.69"},{"v":0.850229304064343,"d":"0.85"},{"v":-0.234076111022319,"d":"-0.23"},{"v":0.46143756987679,"d":"0.46"},{"v":0.893452432692336,"d":"0.89"},"down","no"]
["ENSG00000162636","FAM102B","ENST00000370035;ENST00000483371;ENST00000405454","NA","NA","NA","NA","family with sequence similarity 102 member B [Source:HGNC Symbol;Acc:HGNC:27637]",{"v":2.02813542864778,"d":"2.03"},{"v":1.20268007621593,"d":"1.20"},{"v":1.68634657608118,"d":"1.69"},{"v":0.753901067839894,"d":"0.75"},{"v":0.46355951518787,"d":"0.46"},{"v":0.895279669029891,"d":"0.90"},"up","no"]
["ENSG00000146282","RARS2","ENST00000369536;ENST00000451155;ENST00000493269;ENST00000497828","GO:0003723(RNA binding);GO:0005737(cytoplasm);GO:0006412(translation);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0005739(mitochondrion);GO:0016874(ligase activity);GO:0005759(mitochondrial matrix);GO:0004812(aminoacyl-tRNA ligase activity);GO:0006418(tRNA aminoacylation for protein translation);GO:0004814(arginine-tRNA ligase activity);GO:0006420(arginyl-tRNA aminoacylation);GO:0032543(mitochondrial translation);GO:0032543(mitochondrial translation)","00970(Aminoacyl-tRNA biosynthesis);00970(Aminoacyl-tRNA biosynthesis)","K01887","EC:6.1.1.19","arginyl-tRNA synthetase 2, mitochondrial [Source:HGNC Symbol;Acc:HGNC:21406]",{"v":4.85071061611002,"d":"4.85"},{"v":5.62414827111984,"d":"5.62"},{"v":0.862479149246217,"d":"0.86"},{"v":-0.213438515376083,"d":"-0.21"},{"v":0.464369580523033,"d":"0.46"},{"v":0.895548960563104,"d":"0.90"},"down","no"]
["MSTRG.12600","RNF130","ENST00000522208;ENST00000521389;ENST00000519708;MSTRG.12600.2;ENST00000520911;ENST00000521901;ENST00000261947;ENST00000523487;ENST00000520564","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0016740(transferase activity);GO:0016567(protein ubiquitination);GO:0006915(apoptotic process);GO:0004842(ubiquitin-protein transferase activity);GO:0012501(programmed cell death);GO:0012501(programmed cell death)","NA","NA","NA","ring finger protein 130 [Source:HGNC Symbol;Acc:HGNC:18280]",{"v":10.3691935472313,"d":"10.37"},{"v":11.9829543051807,"d":"11.98"},{"v":0.86532863959502,"d":"0.87"},{"v":-0.208679942867179,"d":"-0.21"},{"v":0.465892084937639,"d":"0.47"},{"v":0.896159458226321,"d":"0.90"},"down","no"]
["ENSG00000180011","ZADH2","ENST00000322342;ENST00000581620;ENST00000537114","GO:0008270(zinc ion binding);GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0005777(peroxisome);GO:0003674(molecular_function);GO:0008150(biological_process);GO:0045599(negative regulation of fat cell differentiation);GO:0036132(13-prostaglandin reductase activity);GO:0047522(15-oxoprostaglandin 13-oxidase activity);GO:0006693(prostaglandin metabolic process);GO:0005739(mitochondrion);GO:0005739(mitochondrion)","NA","NA","NA","zinc binding alcohol dehydrogenase domain containing 2 [Source:HGNC Symbol;Acc:HGNC:28697]",{"v":2.95711849552532,"d":"2.96"},{"v":1.76188334878019,"d":"1.76"},{"v":1.67838494958967,"d":"1.68"},{"v":0.747073646153594,"d":"0.75"},{"v":0.468066431379526,"d":"0.47"},{"v":0.897359197804506,"d":"0.90"},"up","no"]
["MSTRG.14467","NDUFAF6","ENST00000396124;ENST00000523337;ENST00000517976;ENST00000518608;ENST00000520757;ENST00000519136;ENST00000518258;ENST00000521587;ENST00000523378;ENST00000521840;ENST00000521063;ENST00000454358;ENST00000396113;ENST00000520632;ENST00000522683","GO:0009058(biosynthetic process);GO:0016740(transferase activity);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005743(mitochondrial inner membrane);GO:0005739(mitochondrion);GO:0032981(mitochondrial respiratory chain complex I assembly);GO:0032981(mitochondrial respiratory chain complex I assembly)","NA","NA","NA","NADH:ubiquinone oxidoreductase complex assembly factor 6 [Source:HGNC Symbol;Acc:HGNC:28625]",{"v":0.359064234467687,"d":"0.36"},{"v":0.422393727443022,"d":"0.42"},{"v":0.850069996638675,"d":"0.85"},{"v":-0.234346454053769,"d":"-0.23"},{"v":0.468268273330433,"d":"0.47"},{"v":0.897359646565399,"d":"0.90"},"down","no"]
["ENSG00000101019","UQCC1","ENST00000397554;ENST00000374385;ENST00000496812;ENST00000482440;ENST00000495752;ENST00000473982;ENST00000374384;ENST00000443429;ENST00000497717;ENST00000438533;ENST00000424405;ENST00000472559;ENST00000374394;ENST00000491040","GO:0016020(membrane);GO:0005743(mitochondrial inner membrane);GO:0005739(mitochondrion);GO:0031410(cytoplasmic vesicle);GO:0005515(protein binding);GO:0070131(positive regulation of mitochondrial translation);GO:0034551(mitochondrial respiratory chain complex III assembly);GO:0034551(mitochondrial respiratory chain complex III assembly)","NA","NA","NA","ubiquinol-cytochrome c reductase complex assembly factor 1 [Source:HGNC Symbol;Acc:HGNC:15891]",{"v":1.65487660513123,"d":"1.65"},{"v":1.91053179003244,"d":"1.91"},{"v":0.866186374791037,"d":"0.87"},{"v":-0.207250616058428,"d":"-0.21"},{"v":0.470001387069636,"d":"0.47"},{"v":0.897524880945525,"d":"0.90"},"down","no"]
["ENSG00000169016","E2F6","ENST00000381525;ENST00000546212;ENST00000471343;ENST00000444832;ENST00000542100;ENST00000498701;ENST00000437573;ENST00000307236;ENST00000455198;ENST00000468775;ENST00000421117","GO:0005634(nucleus);GO:0005730(nucleolus);GO:0046983(protein dimerization activity);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0005515(protein binding);GO:0007049(cell cycle);GO:0005667(transcription factor complex);GO:0000083(regulation of transcription involved in G1/S transition of mitotic cell cycle);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0003714(transcription corepressor activity);GO:0071339(MLL1 complex);GO:0000977(RNA polymerase II regulatory region sequence-specific DNA binding);GO:0090575(RNA polymerase II transcription factor complex);GO:0001227(transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding);GO:0001227(transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding)","NA","NA","NA","E2F transcription factor 6 [Source:HGNC Symbol;Acc:HGNC:3120]",{"v":0.779671834029998,"d":"0.78"},{"v":0.907797281042537,"d":"0.91"},{"v":0.858861169020691,"d":"0.86"},{"v":-0.219503149731472,"d":"-0.22"},{"v":0.470836016213841,"d":"0.47"},{"v":0.898130528300154,"d":"0.90"},"down","no"]
["ENSG00000162813","BPNT1","ENST00000322067;ENST00000498237;ENST00000544404;ENST00000463953;ENST00000498791;ENST00000482136;ENST00000354807;ENST00000414869;ENST00000548668","GO:0046872(metal ion binding);GO:0016787(hydrolase activity);GO:0016311(dephosphorylation);GO:0046854(phosphatidylinositol phosphorylation);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0006139(nucleobase-containing compound metabolic process);GO:0007399(nervous system development);GO:0050427(3'-phosphoadenosine 5'-phosphosulfate metabolic process);GO:0008441(3'(2'),5'-bisphosphate nucleotidase activity);GO:0008441(3'(2'),5'-bisphosphate nucleotidase activity)","00920(Sulfur metabolism);00920(Sulfur metabolism)","K01082","EC:3.1.3.7","3'(2'), 5'-bisphosphate nucleotidase 1 [Source:HGNC Symbol;Acc:HGNC:1096]",{"v":2.55165863283007,"d":"2.55"},{"v":2.94391139640218,"d":"2.94"},{"v":0.866757958798797,"d":"0.87"},{"v":-0.206298916194368,"d":"-0.21"},{"v":0.47272082637694,"d":"0.47"},{"v":0.898425237395212,"d":"0.90"},"down","no"]
["MSTRG.11736","METAP1","ENST00000296411;ENST00000513097;ENST00000513199;ENST00000503247;ENST00000510107;ENST00000510209","GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0016787(hydrolase activity);GO:0008233(peptidase activity);GO:0006508(proteolysis);GO:0008235(metalloexopeptidase activity);GO:0004177(aminopeptidase activity);GO:0005829(cytosol);GO:0070527(platelet aggregation);GO:0022400(regulation of rhodopsin mediated signaling pathway);GO:0018206(peptidyl-methionine modification);GO:0031365(N-terminal protein amino acid modification);GO:0006417(regulation of translation);GO:0006417(regulation of translation)","NA","NA","NA","methionyl aminopeptidase 1 [Source:HGNC Symbol;Acc:HGNC:15789]",{"v":5.95093976997814,"d":"5.95"},{"v":6.84381790017003,"d":"6.84"},{"v":0.869535083601551,"d":"0.87"},{"v":-0.201683856985325,"d":"-0.20"},{"v":0.474079325572316,"d":"0.47"},{"v":0.898425237395212,"d":"0.90"},"down","no"]
["MSTRG.5355","MESD;AC027808.1;AC027808.2","ENST00000261758;ENST00000560244;ENST00000560189;ENST00000560873;ENST00000422879;ENST00000558261;ENST00000619987","GO:0006457(protein folding);GO:0005783(endoplasmic reticulum);GO:0016055(Wnt signaling pathway);GO:0003674(molecular_function);GO:0005575(cellular_component);GO:0007498(mesoderm development);GO:0050750(low-density lipoprotein particle receptor binding);GO:0034394(protein localization to cell surface);GO:0005886(plasma membrane);GO:0005886(plasma membrane)","NA","NA","NA","mesoderm development LRP chaperone [Source:HGNC Symbol;Acc:HGNC:13520]",{"v":1.93512349376136,"d":"1.94"},{"v":2.22764248431254,"d":"2.23"},{"v":0.868686742773514,"d":"0.87"},{"v":-0.203092074491511,"d":"-0.20"},{"v":0.474639412354488,"d":"0.47"},{"v":0.898425237395212,"d":"0.90"},"down","no"]
["MSTRG.12699","DEK","ENST00000397239;ENST00000507591;ENST00000244776;ENST00000515742;ENST00000503715;ENST00000512145;ENST00000515770;ENST00000505224;MSTRG.12699.4","GO:0003723(RNA binding);GO:0005634(nucleus);GO:0016569(covalent chromatin modification);GO:0003677(DNA binding);GO:0003682(chromatin binding);GO:0005654(nucleoplasm);GO:0006338(chromatin remodeling);GO:0045815(positive regulation of gene expression, epigenetic);GO:0007165(signal transduction);GO:0042393(histone binding);GO:0006366(transcription from RNA polymerase II promoter);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0019079(viral genome replication);GO:2000779(regulation of double-strand break repair);GO:2001032(regulation of double-strand break repair via nonhomologous end joining);GO:0043292(contractile fiber);GO:0043292(contractile fiber)","NA","NA","NA","DEK proto-oncogene [Source:HGNC Symbol;Acc:HGNC:2768]",{"v":13.3075563611557,"d":"13.31"},{"v":15.2690375783077,"d":"15.27"},{"v":0.871538647600251,"d":"0.87"},{"v":-0.198363454099265,"d":"-0.20"},{"v":0.475838806718944,"d":"0.48"},{"v":0.898425237395212,"d":"0.90"},"down","no"]
["MSTRG.2696","FCHSD2","ENST00000409418;ENST00000543644;ENST00000409263;ENST00000409853;ENST00000409314;ENST00000422375;ENST00000432043","GO:0005515(protein binding);GO:0031594(neuromuscular junction);GO:0055037(recycling endosome);GO:0007274(neuromuscular synaptic transmission);GO:0030833(regulation of actin filament polymerization);GO:0030833(regulation of actin filament polymerization)","NA","NA","NA","FCH and double SH3 domains 2 [Source:HGNC Symbol;Acc:HGNC:29114]",{"v":6.90783842791056,"d":"6.91"},{"v":4.14758786276022,"d":"4.15"},{"v":1.66550743624594,"d":"1.67"},{"v":0.735961795447985,"d":"0.74"},{"v":0.476702714178022,"d":"0.48"},{"v":0.898476806983127,"d":"0.90"},"up","no"]
["MSTRG.12396","NDUFA2","ENST00000252102;ENST00000510680;ENST00000512088;ENST00000502960","GO:0016020(membrane);GO:0055114(oxidation-reduction process);GO:0005743(mitochondrial inner membrane);GO:0005739(mitochondrion);GO:0070469(respiratory chain);GO:0031966(mitochondrial membrane);GO:0032981(mitochondrial respiratory chain complex I assembly);GO:0008137(NADH dehydrogenase (ubiquinone) activity);GO:0006120(mitochondrial electron transport, NADH to ubiquinone);GO:0005747(mitochondrial respiratory chain complex I);GO:0005747(mitochondrial respiratory chain complex I)","00190(Oxidative phosphorylation);04723(Retrograde endocannabinoid signaling);05010(Alzheimer's disease);05012(Parkinson's disease);05016(Huntington's disease);04932(Non-alcoholic fatty liver disease (NAFLD));04932(Non-alcoholic fatty liver disease (NAFLD))","K03946","NA","NADH:ubiquinone oxidoreductase subunit A2 [Source:HGNC Symbol;Acc:HGNC:7685]",{"v":6.26921338172043,"d":"6.27"},{"v":7.20798353830645,"d":"7.21"},{"v":0.869759669733293,"d":"0.87"},{"v":-0.201311281492074,"d":"-0.20"},{"v":0.477688066391884,"d":"0.48"},{"v":0.898799662185507,"d":"0.90"},"down","no"]
["MSTRG.9533","SEPT2","ENST00000391973;ENST00000407971;ENST00000391971;ENST00000445030;ENST00000425899;MSTRG.9533.22;ENST00000429791;ENST00000402092;ENST00000484740;ENST00000407017;ENST00000476841;ENST00000457874;ENST00000437066;ENST00000401990;ENST00000616972;ENST00000449239;ENST00000482304;ENST00000441533;ENST00000484167;ENST00000420786;ENST00000495463;ENST00000473479;ENST00000467971;ENST00000461048;ENST00000469175;ENST00000457335;ENST00000462147;ENST00000484648;ENST00000411484;ENST00000466211;ENST00000434955;ENST00000469434;ENST00000366210;ENST00000481500;ENST00000421717;ENST00000475474;ENST00000443492;ENST00000464128;ENST00000492978;ENST00000451310","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005525(GTP binding);GO:0000166(nucleotide binding);GO:0005730(nucleolus);GO:0005829(cytosol);GO:0051301(cell division);GO:0005694(chromosome);GO:0005886(plasma membrane);GO:0015629(actin cytoskeleton);GO:0005856(cytoskeleton);GO:0042995(cell projection);GO:0005515(protein binding);GO:0007049(cell cycle);GO:0030154(cell differentiation);GO:0007283(spermatogenesis);GO:0005819(spindle);GO:0030496(midbody);GO:0000775(chromosome, centromeric region);GO:0000776(kinetochore);GO:0000777(condensed chromosome kinetochore);GO:0007224(smoothened signaling pathway);GO:0060271(cilium assembly);GO:0045296(cadherin binding);GO:0070062(extracellular exosome);GO:0005938(cell cortex);GO:0032154(cleavage furrow);GO:0060170(ciliary membrane);GO:0031105(septin complex);GO:0097227(sperm annulus);GO:0005930(axoneme);GO:0032391(photoreceptor connecting cilium);GO:0097730(non-motile cilium);GO:0031175(neuron projection development);GO:0000145(exocyst);GO:0048471(perinuclear region of cytoplasm);GO:0048471(perinuclear region of cytoplasm)","05100(Bacterial invasion of epithelial cells);05100(Bacterial invasion of epithelial cells)","K16942","NA","septin 2 [Source:HGNC Symbol;Acc:HGNC:7729]",{"v":14.5174375693955,"d":"14.52"},{"v":16.6351012861209,"d":"16.64"},{"v":0.872699078875328,"d":"0.87"},{"v":-0.19644382047658,"d":"-0.20"},{"v":0.478547582513743,"d":"0.48"},{"v":0.899096133520778,"d":"0.90"},"down","no"]
["MSTRG.12707","ALDH5A1","ENST00000357578;ENST00000348925;ENST00000479394;ENST00000492697","GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0005739(mitochondrion);GO:0008152(metabolic process);GO:0042803(protein homodimerization activity);GO:0006541(glutamine metabolic process);GO:0005759(mitochondrial matrix);GO:0006650(glycerophospholipid metabolic process);GO:0006006(glucose metabolic process);GO:0009013(succinate-semialdehyde dehydrogenase [NAD(P)+] activity);GO:0009450(gamma-aminobutyric acid catabolic process);GO:0051289(protein homotetramerization);GO:0006749(glutathione metabolic process);GO:0007417(central nervous system development);GO:0006536(glutamate metabolic process);GO:0042135(neurotransmitter catabolic process);GO:0006105(succinate metabolic process);GO:0022904(respiratory electron transport chain);GO:0004777(succinate-semialdehyde dehydrogenase (NAD+) activity);GO:0051287(NAD binding);GO:0006083(acetate metabolic process);GO:0006540(glutamate decarboxylation to succinate);GO:0006681(galactosylceramide metabolic process);GO:0046459(short-chain fatty acid metabolic process);GO:0006678(glucosylceramide metabolic process);GO:0009448(gamma-aminobutyric acid metabolic process);GO:0009791(post-embryonic development);GO:0009791(post-embryonic development)","00650(Butanoate metabolism);00250(Alanine, aspartate and glutamate metabolism);00250(Alanine, aspartate and glutamate metabolism)","K00139","EC:1.2.1.24","aldehyde dehydrogenase 5 family member A1 [Source:HGNC Symbol;Acc:HGNC:408]",{"v":1.4170024720362,"d":"1.42"},{"v":0.846036248687783,"d":"0.85"},{"v":1.67487205688172,"d":"1.67"},{"v":0.744050892613869,"d":"0.74"},{"v":0.480494061146431,"d":"0.48"},{"v":0.900141560266737,"d":"0.90"},"up","no"]
["MSTRG.7595","ARHGAP45","ENST00000590577;ENST00000313093;ENST00000586866;ENST00000586378;ENST00000591169;ENST00000590214;ENST00000592297;ENST00000539243;ENST00000590512;ENST00000543365;ENST00000586937;ENST00000587602;ENST00000591293;ENST00000586033;ENST00000587186;ENST00000592335","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0046872(metal ion binding);GO:0035556(intracellular signal transduction);GO:0007165(signal transduction);GO:0005886(plasma membrane);GO:0043547(positive regulation of GTPase activity);GO:0042995(cell projection);GO:0005515(protein binding);GO:0005096(GTPase activator activity);GO:0005576(extracellular region);GO:0005829(cytosol);GO:0051056(regulation of small GTPase mediated signal transduction);GO:0032587(ruffle membrane);GO:0043312(neutrophil degranulation);GO:0034774(secretory granule lumen);GO:0035578(azurophil granule lumen);GO:0005622(intracellular);GO:0005622(intracellular)","NA","NA","NA","Rho GTPase activating protein 45 [Source:HGNC Symbol;Acc:HGNC:17102]",{"v":53.0309156514909,"d":"53.03"},{"v":31.9584970434434,"d":"31.96"},{"v":1.65936826063511,"d":"1.66"},{"v":0.730634096561279,"d":"0.73"},{"v":0.481593963494707,"d":"0.48"},{"v":0.900203705653762,"d":"0.90"},"up","no"]
["MSTRG.2322","PDHX","ENST00000227868;ENST00000532159;ENST00000448838;ENST00000477173;ENST00000430469;ENST00000533550","GO:0016746(transferase activity, transferring acyl groups);GO:0008152(metabolic process);GO:0005739(mitochondrion);GO:0005515(protein binding);GO:0005759(mitochondrial matrix);GO:0034641(cellular nitrogen compound metabolic process);GO:0034604(pyruvate dehydrogenase (NAD+) activity);GO:0006090(pyruvate metabolic process);GO:0010510(regulation of acetyl-CoA biosynthetic process from pyruvate);GO:0061732(mitochondrial acetyl-CoA biosynthetic process from pyruvate);GO:0045254(pyruvate dehydrogenase complex);GO:0045254(pyruvate dehydrogenase complex)","00010(Glycolysis / Gluconeogenesis);00020(Citrate cycle (TCA cycle));00620(Pyruvate metabolism);00620(Pyruvate metabolism)","K13997","NA","pyruvate dehydrogenase complex component X [Source:HGNC Symbol;Acc:HGNC:21350]",{"v":1.47179103696809,"d":"1.47"},{"v":1.68610452393617,"d":"1.69"},{"v":0.872894305230989,"d":"0.87"},{"v":-0.196121119784768,"d":"-0.20"},{"v":0.482946309372106,"d":"0.48"},{"v":0.900203705653762,"d":"0.90"},"down","no"]
["MSTRG.9755","OSER1-AS1","ENST00000439943;ENST00000435163;ENST00000442383;ENST00000623343;ENST00000437730","NA","NA","NA","NA","OSER1 antisense RNA 1 (head to head) [Source:HGNC Symbol;Acc:HGNC:48585]",{"v":4.18214835452882,"d":"4.18"},{"v":2.51203154254346,"d":"2.51"},{"v":1.66484707046885,"d":"1.66"},{"v":0.735389660293994,"d":"0.74"},{"v":0.483980899035466,"d":"0.48"},{"v":0.900203705653762,"d":"0.90"},"up","no"]
["MSTRG.10610","TYMP;SCO2;ODF3B","MSTRG.10610.2;ENST00000487577;ENST00000487162;ENST00000535425;ENST00000476284;MSTRG.10610.9;ENST00000425169;ENST00000395680;MSTRG.10610.1;ENST00000437588;ENST00000463472;ENST00000395693;ENST00000468249;ENST00000252785;ENST00000543927;ENST00000403326;ENST00000428989;ENST00000329363;ENST00000405135;ENST00000395681;MSTRG.10610.14;ENST00000395678;ENST00000252029;ENST00000401779;ENST00000469660","GO:0016740(transferase activity);GO:0016757(transferase activity, transferring glycosyl groups);GO:0008083(growth factor activity);GO:0008152(metabolic process);GO:0007275(multicellular organism development);GO:0030154(cell differentiation);GO:0006935(chemotaxis);GO:0016763(transferase activity, transferring pentosyl groups);GO:0004645(phosphorylase activity);GO:0006206(pyrimidine nucleobase metabolic process);GO:0006213(pyrimidine nucleoside metabolic process);GO:0005829(cytosol);GO:0009032(thymidine phosphorylase activity);GO:0016154(pyrimidine-nucleoside phosphorylase activity);GO:0043097(pyrimidine nucleoside salvage);GO:0001525(angiogenesis);GO:0042803(protein homodimerization activity);GO:0046135(pyrimidine nucleoside catabolic process);GO:0000002(mitochondrial genome maintenance);GO:0031641(regulation of myelination);GO:0051969(regulation of transmission of nerve impulse);GO:1905333(regulation of gastric motility);GO:0046872(metal ion binding);GO:0055114(oxidation-reduction process);GO:0045454(cell redox homeostasis);GO:0005739(mitochondrion);GO:0005743(mitochondrial inner membrane);GO:0005507(copper ion binding);GO:0005515(protein binding);GO:0001654(eye development);GO:0005759(mitochondrial matrix);GO:0006825(copper ion transport);GO:0006878(cellular copper ion homeostasis);GO:0008535(respiratory chain complex IV assembly);GO:0030016(myofibril);GO:1905333(regulation of gastric motility)","00240(Pyrimidine metabolism);00983(Drug metabolism - other enzymes);05219(Bladder cancer);05230(Central carbon metabolism in cancer);05219(Bladder cancer)","K07152;K00758","EC:2.4.2.4","thymidine phosphorylase [Source:HGNC Symbol;Acc:HGNC:3148];SCO2, cytochrome c oxidase assembly protein [Source:NCBI gene;Acc:9997];outer dense fiber of sperm tails 3B [Source:HGNC Symbol;Acc:HGNC:34388];SCO2, cytochrome c oxidase assembly protein [Source:HGNC Symbol;Acc:HGNC:10604]",{"v":19.6946521948741,"d":"19.69"},{"v":22.4536607473855,"d":"22.45"},{"v":0.877124332484062,"d":"0.88"},{"v":-0.189146735519014,"d":"-0.19"},{"v":0.4843081331936,"d":"0.48"},{"v":0.900351074590347,"d":"0.90"},"down","no"]
["MSTRG.10423","TST","ENST00000249042;ENST00000403892","GO:0003723(RNA binding);GO:0016740(transferase activity);GO:0005739(mitochondrion);GO:0005615(extracellular space);GO:0005759(mitochondrial matrix);GO:0004792(thiosulfate sulfurtransferase activity);GO:0070062(extracellular exosome);GO:0030855(epithelial cell differentiation);GO:0009440(cyanate catabolic process);GO:0008097(5S rRNA binding);GO:0035928(rRNA import into mitochondrion);GO:0051029(rRNA transport);GO:0005743(mitochondrial inner membrane);GO:0005743(mitochondrial inner membrane)","00920(Sulfur metabolism);00270(Cysteine and methionine metabolism);04122(Sulfur relay system);04122(Sulfur relay system)","K01011","EC:2.8.1.1;EC:2.8.1.2","thiosulfate sulfurtransferase [Source:HGNC Symbol;Acc:HGNC:12388]",{"v":4.81268673618998,"d":"4.81"},{"v":5.48851262364481,"d":"5.49"},{"v":0.876865385251491,"d":"0.88"},{"v":-0.189572715086874,"d":"-0.19"},{"v":0.487602258679153,"d":"0.49"},{"v":0.902451695174006,"d":"0.90"},"down","no"]
["MSTRG.6497","FLII","ENST00000327031;MSTRG.6497.1;ENST00000493401;ENST00000580966;ENST00000487369;ENST00000459958;ENST00000493600;ENST00000577402;ENST00000473425;ENST00000578558;ENST00000478416;ENST00000580453;ENST00000582626;ENST00000465046;ENST00000488932;ENST00000581401;ENST00000461110;ENST00000474265;ENST00000545457;ENST00000496727;ENST00000577626;ENST00000577485;ENST00000577398;ENST00000487693;ENST00000488221","GO:0051015(actin filament binding);GO:0030036(actin cytoskeleton organization);GO:0051014(actin filament severing);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0005815(microtubule organizing center);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003779(actin binding);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0007275(multicellular organism development);GO:0030054(cell junction);GO:0005925(focal adhesion);GO:0005903(brush border);GO:0005903(brush border)","NA","NA","NA","FLII, actin remodeling protein [Source:HGNC Symbol;Acc:HGNC:3750]",{"v":23.4293942623942,"d":"23.43"},{"v":14.1760365850967,"d":"14.18"},{"v":1.65274645855708,"d":"1.65"},{"v":0.724865423337063,"d":"0.72"},{"v":0.487732512489966,"d":"0.49"},{"v":0.902451695174006,"d":"0.90"},"up","no"]
["MSTRG.7513","ACAA2;MYO5B","ENST00000285093;ENST00000285039;ENST00000591171;ENST00000587994","GO:0003723(RNA binding);GO:0016740(transferase activity);GO:0005739(mitochondrion);GO:0003824(catalytic activity);GO:0016746(transferase activity, transferring acyl groups);GO:0006629(lipid metabolic process);GO:0008152(metabolic process);GO:0006631(fatty acid metabolic process);GO:0016747(transferase activity, transferring acyl groups other than amino-acyl groups);GO:0005515(protein binding);GO:0006695(cholesterol biosynthetic process);GO:0070062(extracellular exosome);GO:0005759(mitochondrial matrix);GO:1901029(negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway);GO:0006635(fatty acid beta-oxidation);GO:0071456(cellular response to hypoxia);GO:0003988(acetyl-CoA C-acyltransferase activity);GO:1902109(negative regulation of mitochondrial membrane permeability involved in apoptotic process);GO:0005743(mitochondrial inner membrane);GO:0006810(transport);GO:0005737(cytoplasm);GO:0015031(protein transport);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0003774(motor activity);GO:0016459(myosin complex);GO:0003779(actin binding);GO:0016192(vesicle-mediated transport);GO:0005516(calmodulin binding);GO:0043234(protein complex);GO:0055037(recycling endosome);GO:0017137(Rab GTPase binding);GO:0003091(renal water homeostasis);GO:0030659(cytoplasmic vesicle membrane);GO:0032439(endosome localization);GO:0000146(microfilament motor activity);GO:0045179(apical cortex);GO:0005743(mitochondrial inner membrane)","00062(Fatty acid elongation);00071(Fatty acid degradation);00280(Valine, leucine and isoleucine degradation);00280(Valine, leucine and isoleucine degradation)","K07508","EC:2.3.1.16","acetyl-CoA acyltransferase 2 [Source:HGNC Symbol;Acc:HGNC:83];myosin VB [Source:HGNC Symbol;Acc:HGNC:7603]",{"v":1.33492630597686,"d":"1.33"},{"v":1.51873049800771,"d":"1.52"},{"v":0.878975109624804,"d":"0.88"},{"v":-0.186105782453024,"d":"-0.19"},{"v":0.48904303373923,"d":"0.49"},{"v":0.902526788577859,"d":"0.90"},"down","no"]
["MSTRG.11774","UBE2D3","ENST00000502563;ENST00000343106;ENST00000453744;ENST00000503742;ENST00000508474;ENST00000618836;ENST00000394803;ENST00000394801;ENST00000505307;ENST00000513098;ENST00000503418;ENST00000321805;ENST00000349311;ENST00000508635;ENST00000508818;ENST00000357194;ENST00000394804;ENST00000510129;ENST00000350435;ENST00000510599;ENST00000508249;ENST00000508476;ENST00000505009;ENST00000504211;ENST00000507845;ENST00000514755;ENST00000505207;ENST00000338145;ENST00000503282;ENST00000508974","GO:0016020(membrane);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0016740(transferase activity);GO:0016567(protein ubiquitination);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0006281(DNA repair);GO:0006974(cellular response to DNA damage stimulus);GO:0006915(apoptotic process);GO:0005768(endosome);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0061631(ubiquitin conjugating enzyme activity);GO:0061418(regulation of transcription from RNA polymerase II promoter in response to hypoxia);GO:0010008(endosome membrane);GO:0035666(TRIF-dependent toll-like receptor signaling pathway);GO:0004842(ubiquitin-protein transferase activity);GO:0030509(BMP signaling pathway);GO:0006464(cellular protein modification process);GO:0043161(proteasome-mediated ubiquitin-dependent protein catabolic process);GO:0070936(protein K48-linked ubiquitination);GO:0070979(protein K11-linked ubiquitination);GO:1903955(positive regulation of protein targeting to mitochondrion);GO:0006511(ubiquitin-dependent protein catabolic process);GO:0000209(protein polyubiquitination);GO:0006513(protein monoubiquitination);GO:0051865(protein autoubiquitination);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0000122(negative regulation of transcription from RNA polymerase II promoter)","04141(Protein processing in endoplasmic reticulum);04120(Ubiquitin mediated proteolysis);04120(Ubiquitin mediated proteolysis)","K06689","EC:2.3.2.23","ubiquitin conjugating enzyme E2 D3 [Source:HGNC Symbol;Acc:HGNC:12476]",{"v":25.6476469104181,"d":"25.65"},{"v":29.1018447943192,"d":"29.10"},{"v":0.881306566359828,"d":"0.88"},{"v":-0.182284140630119,"d":"-0.18"},{"v":0.490449153915424,"d":"0.49"},{"v":0.902628530018989,"d":"0.90"},"down","no"]
["ENSG00000105227","PRX","ENST00000291825;ENST00000599513;ENST00000324001","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0030054(cell junction);GO:0003674(molecular_function);GO:0008366(axon ensheathment);GO:0008366(axon ensheathment)","NA","NA","NA","periaxin [Source:HGNC Symbol;Acc:HGNC:13797]",{"v":0.418170885555748,"d":"0.42"},{"v":0.248288363794,"d":"0.25"},{"v":1.6842145929267,"d":"1.68"},{"v":0.752075970011849,"d":"0.75"},{"v":0.491862343196359,"d":"0.49"},{"v":0.903646685897658,"d":"0.90"},"up","no"]
["ENSG00000166387","PPFIBP2","ENST00000299492;ENST00000532416;ENST00000529321;ENST00000528929;ENST00000530582;ENST00000526873;ENST00000534409;ENST00000532381;ENST00000532112;ENST00000532926;ENST00000529021;ENST00000529664;ENST00000534552","GO:0005615(extracellular space);GO:0003674(molecular_function);GO:0005829(cytosol);GO:0005622(intracellular);GO:0042802(identical protein binding);GO:0042802(identical protein binding)","NA","NA","NA","PPFIA binding protein 2 [Source:HGNC Symbol;Acc:HGNC:9250]",{"v":0.815576787875637,"d":"0.82"},{"v":0.929528922013102,"d":"0.93"},{"v":0.87740872667988,"d":"0.88"},{"v":-0.188679039458899,"d":"-0.19"},{"v":0.493414732036466,"d":"0.49"},{"v":0.904512211599345,"d":"0.90"},"down","no"]
["MSTRG.425","MEAF6","ENST00000475828;ENST00000296214;ENST00000373075;ENST00000373073;ENST00000485039;ENST00000448519;ENST00000373074;ENST00000487792","GO:0005634(nucleus);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0016569(covalent chromatin modification);GO:0005694(chromosome);GO:0005515(protein binding);GO:0000123(histone acetyltransferase complex);GO:0016604(nuclear body);GO:0005730(nucleolus);GO:0000775(chromosome, centromeric region);GO:0000776(kinetochore);GO:0000777(condensed chromosome kinetochore);GO:0016573(histone acetylation);GO:1901796(regulation of signal transduction by p53 class mediator);GO:0043981(histone H4-K5 acetylation);GO:0043982(histone H4-K8 acetylation);GO:0043983(histone H4-K12 acetylation);GO:0043968(histone H2A acetylation);GO:0035267(NuA4 histone acetyltransferase complex);GO:0070776(MOZ/MORF histone acetyltransferase complex);GO:0044154(histone H3-K14 acetylation);GO:0044154(histone H3-K14 acetylation)","NA","NA","NA","MYST/Esa1 associated factor 6 [Source:HGNC Symbol;Acc:HGNC:25674]",{"v":7.86201576082592,"d":"7.86"},{"v":8.90336559764841,"d":"8.90"},{"v":0.883038630122351,"d":"0.88"},{"v":-0.179451542328582,"d":"-0.18"},{"v":0.493974186393601,"d":"0.49"},{"v":0.904512211599345,"d":"0.90"},"down","no"]
["MSTRG.8307","CD37","ENST00000323906;ENST00000535669;ENST00000426897;ENST00000391859;ENST00000595725;ENST00000597852;ENST00000598095;ENST00000594743;ENST00000596426;ENST00000598134;ENST00000597033;ENST00000595660;ENST00000593512;ENST00000600121;ENST00000597602","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005515(protein binding);GO:0005887(integral component of plasma membrane);GO:0070062(extracellular exosome);GO:0007166(cell surface receptor signaling pathway);GO:0001772(immunological synapse);GO:0001772(immunological synapse)","04640(Hematopoietic cell lineage);04640(Hematopoietic cell lineage)","K06475","NA","CD37 molecule [Source:HGNC Symbol;Acc:HGNC:1666]",{"v":64.2053623732276,"d":"64.21"},{"v":39.0739718440279,"d":"39.07"},{"v":1.64317471050849,"d":"1.64"},{"v":0.716485882956219,"d":"0.72"},{"v":0.494950897251307,"d":"0.49"},{"v":0.904512211599345,"d":"0.90"},"up","no"]
["ENSG00000166275","BORCS7","ENST00000339834;ENST00000369883;ENST00000478833","GO:0016020(membrane);GO:0005765(lysosomal membrane);GO:0005764(lysosome);GO:0005515(protein binding);GO:0099078(BORC complex);GO:0099078(BORC complex)","NA","NA","NA","BLOC-1 related complex subunit 7 [Source:HGNC Symbol;Acc:HGNC:23516]",{"v":2.41104701107829,"d":"2.41"},{"v":2.73808678581979,"d":"2.74"},{"v":0.880559017911631,"d":"0.88"},{"v":-0.183508393505462,"d":"-0.18"},{"v":0.496409957159253,"d":"0.50"},{"v":0.90561412808564,"d":"0.91"},"down","no"]
["ENSG00000130147","SH3BP4","ENST00000409212","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0032007(negative regulation of TOR signaling);GO:0005515(protein binding);GO:0031410(cytoplasmic vesicle);GO:0005905(clathrin-coated pit);GO:0017016(Ras GTPase binding);GO:0042802(identical protein binding);GO:0071230(cellular response to amino acid stimulus);GO:0006897(endocytosis);GO:0070062(extracellular exosome);GO:0010508(positive regulation of autophagy);GO:0008285(negative regulation of cell proliferation);GO:0050790(regulation of catalytic activity);GO:0030308(negative regulation of cell growth);GO:0030136(clathrin-coated vesicle);GO:0005092(GDP-dissociation inhibitor activity);GO:0061462(protein localization to lysosome);GO:0034260(negative regulation of GTPase activity)","NA","NA","NA","SH3 domain binding protein 4 [Source:HGNC Symbol;Acc:HGNC:10826]",{"v":0.251959711039417,"d":"0.25"},{"v":0.151992505400477,"d":"0.15"},{"v":1.6577114139644,"d":"1.66"},{"v":0.729192874215956,"d":"0.73"},{"v":0.498608272303119,"d":"0.50"},{"v":0.907133091771395,"d":"0.91"},"up","no"]
["MSTRG.5079","TMOD3","ENST00000308580;ENST00000561438;ENST00000558300;ENST00000560725;ENST00000561408;ENST00000558455;ENST00000560549;ENST00000561136;ENST00000558666;ENST00000558714","GO:0030036(actin cytoskeleton organization);GO:0048821(erythrocyte development);GO:0005523(tropomyosin binding);GO:0051694(pointed-end actin filament capping);GO:0005737(cytoplasm);GO:0003779(actin binding);GO:0005856(cytoskeleton);GO:0007015(actin filament organization);GO:0098641(cadherin binding involved in cell-cell adhesion);GO:0098609(cell-cell adhesion);GO:0005913(cell-cell adherens junction);GO:0006936(muscle contraction);GO:0030239(myofibril assembly);GO:0005865(striated muscle thin filament);GO:1901992(positive regulation of mitotic cell cycle phase transition);GO:1901992(positive regulation of mitotic cell cycle phase transition)","NA","NA","NA","tropomodulin 3 [Source:HGNC Symbol;Acc:HGNC:11873]",{"v":5.75898932778405,"d":"5.76"},{"v":3.51543988440557,"d":"3.52"},{"v":1.63819877942753,"d":"1.64"},{"v":0.71211042455814,"d":"0.71"},{"v":0.500713333213906,"d":"0.50"},{"v":0.907952974747628,"d":"0.91"},"up","no"]
["MSTRG.3577","CCDC59","ENST00000550589;ENST00000256151;ENST00000548126;ENST00000547758;ENST00000552606;ENST00000552377","GO:0003723(RNA binding);GO:0005634(nucleus);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0005515(protein binding);GO:0005654(nucleoplasm);GO:0044267(cellular protein metabolic process);GO:0044267(cellular protein metabolic process)","NA","NA","NA","coiled-coil domain containing 59 [Source:HGNC Symbol;Acc:HGNC:25005]",{"v":3.23583291041226,"d":"3.24"},{"v":3.65485461707188,"d":"3.65"},{"v":0.88535201791547,"d":"0.89"},{"v":-0.175676906894514,"d":"-0.18"},{"v":0.50160275152565,"d":"0.50"},{"v":0.907952974747628,"d":"0.91"},"down","no"]
["MSTRG.8838","AC005041.1;C2orf81;HMGA1P8","ENST00000517883;ENST00000290390;ENST00000640868;ENST00000414130","GO:0006355(regulation of transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated)","NA","NA","NA","chromosome 2 open reading frame 81 [Source:HGNC Symbol;Acc:HGNC:34350];high mobility group AT-hook 1 pseudogene 8 [Source:HGNC Symbol;Acc:HGNC:39183]",{"v":0.143609206065915,"d":"0.14"},{"v":0.165434667579109,"d":"0.17"},{"v":0.868072020015047,"d":"0.87"},{"v":-0.204113353360169,"d":"-0.20"},{"v":0.502368096894869,"d":"0.50"},{"v":0.908015674589902,"d":"0.91"},"down","no"]
["MSTRG.13764","PHTF2","ENST00000307305;ENST00000248550;ENST00000468351;ENST00000454592;ENST00000415251;ENST00000275575;ENST00000470215;ENST00000424760;ENST00000450574;ENST00000416283;ENST00000479515","GO:0005634(nucleus);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0005783(endoplasmic reticulum);GO:0005783(endoplasmic reticulum)","NA","NA","NA","putative homeodomain transcription factor 2 [Source:HGNC Symbol;Acc:HGNC:13411]",{"v":2.60034254013417,"d":"2.60"},{"v":1.58731788977562,"d":"1.59"},{"v":1.63819897506589,"d":"1.64"},{"v":0.712110596848878,"d":"0.71"},{"v":0.503183614925367,"d":"0.50"},{"v":0.908499894298552,"d":"0.91"},"up","no"]
["ENSG00000127980","PEX1","ENST00000496420;ENST00000469417;ENST00000422866;ENST00000484913;ENST00000428214;ENST00000477342;ENST00000248633;ENST00000476923;ENST00000496092","GO:0006810(transport);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0015031(protein transport);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0005829(cytosol);GO:0007031(peroxisome organization);GO:0005515(protein binding);GO:0005777(peroxisome);GO:0006625(protein targeting to peroxisome);GO:0005778(peroxisomal membrane);GO:0042623(ATPase activity, coupled);GO:0070062(extracellular exosome);GO:0008022(protein C-terminus binding);GO:0032403(protein complex binding);GO:0016558(protein import into peroxisome matrix);GO:0060152(microtubule-based peroxisome localization);GO:0060152(microtubule-based peroxisome localization)","04146(Peroxisome);04146(Peroxisome)","K13338","NA","peroxisomal biogenesis factor 1 [Source:HGNC Symbol;Acc:HGNC:8850]",{"v":1.47993426920627,"d":"1.48"},{"v":1.67075638323353,"d":"1.67"},{"v":0.885786990884961,"d":"0.89"},{"v":-0.174968285656424,"d":"-0.17"},{"v":0.505742652379023,"d":"0.51"},{"v":0.910289743037445,"d":"0.91"},"down","no"]
["ENSG00000184923","NUTM2A","ENST00000381707;ENST00000381689","NA","NA","NA","NA","NUT family member 2A [Source:HGNC Symbol;Acc:HGNC:23438]",{"v":0.319072819756002,"d":"0.32"},{"v":0.191384835891381,"d":"0.19"},{"v":1.66717921129911,"d":"1.67"},{"v":0.737409193320067,"d":"0.74"},{"v":0.507512768870399,"d":"0.51"},{"v":0.911382286366767,"d":"0.91"},"up","no"]
["ENSG00000107758","PPP3CB","ENST00000360663;ENST00000342558;ENST00000394828;ENST00000394829;ENST00000495897","GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0046872(metal ion binding);GO:0016787(hydrolase activity);GO:0005886(plasma membrane);GO:0004721(phosphoprotein phosphatase activity);GO:0005515(protein binding);GO:0007165(signal transduction);GO:0045893(positive regulation of transcription, DNA-templated);GO:0005509(calcium ion binding);GO:0038095(Fc-epsilon receptor signaling pathway);GO:0005516(calmodulin binding);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0016311(dephosphorylation);GO:0019899(enzyme binding);GO:0050796(regulation of insulin secretion);GO:0006468(protein phosphorylation);GO:0042110(T cell activation);GO:0008144(drug binding);GO:0035690(cellular response to drug);GO:0007612(learning);GO:0048167(regulation of synaptic plasticity);GO:0006470(protein dephosphorylation);GO:0035774(positive regulation of insulin secretion involved in cellular response to glucose stimulus);GO:0007613(memory);GO:0004722(protein serine/threonine phosphatase activity);GO:0007223(Wnt signaling pathway, calcium modulating pathway);GO:0035176(social behavior);GO:0042098(T cell proliferation);GO:0046983(protein dimerization activity);GO:0030346(protein phosphatase 2B binding);GO:0033192(calmodulin-dependent protein phosphatase activity);GO:0017156(calcium ion regulated exocytosis);GO:0033173(calcineurin-NFAT signaling cascade);GO:0048675(axon extension);GO:0005955(calcineurin complex);GO:0001915(negative regulation of T cell mediated cytotoxicity);GO:0001946(lymphangiogenesis);GO:0007507(heart development);GO:0010468(regulation of gene expression);GO:0030217(T cell differentiation);GO:0031987(locomotion involved in locomotory behavior);GO:0034097(response to cytokine);GO:0043029(T cell homeostasis);GO:0030018(Z disc);GO:0030315(T-tubule);GO:0030315(T-tubule)","04010(MAPK signaling pathway);04310(Wnt signaling pathway);04370(VEGF signaling pathway);04020(Calcium signaling pathway);04022(cGMP - PKG signaling pathway);04114(Oocyte meiosis);04218(Cellular senescence);04650(Natural killer cell mediated cytotoxicity);04660(T cell receptor signaling pathway);04658(Th1 and Th2 cell differentiation);04659(Th17 cell differentiation);04662(B cell receptor signaling pathway);04922(Glucagon signaling pathway);04921(Oxytocin signaling pathway);04924(Renin secretion);04724(Glutamatergic synapse);04728(Dopaminergic synapse);04720(Long-term potentiation);04360(Axon guidance);04380(Osteoclast differentiation);05010(Alzheimer's disease);05014(Amyotrophic lateral sclerosis (ALS));05031(Amphetamine addiction);05152(Tuberculosis);05166(HTLV-I infection);05167(Kaposi's sarcoma-associated herpesvirus infection);05167(Kaposi's sarcoma-associated herpesvirus infection)","K04348","EC:3.1.3.16","protein phosphatase 3 catalytic subunit beta [Source:HGNC Symbol;Acc:HGNC:9315]",{"v":4.68503606576364,"d":"4.69"},{"v":5.25397308735768,"d":"5.25"},{"v":0.891712992789583,"d":"0.89"},{"v":-0.165348656611097,"d":"-0.17"},{"v":0.508305942876652,"d":"0.51"},{"v":0.911416392081453,"d":"0.91"},"down","no"]
["MSTRG.1866","TNKS2","ENST00000371627","GO:0048471(perinuclear region of cytoplasm);GO:0005737(cytoplasm);GO:0005634(nucleus);GO:0090263(positive regulation of canonical Wnt signaling pathway);GO:0016020(membrane);GO:0046872(metal ion binding);GO:0016740(transferase activity);GO:0016757(transferase activity, transferring glycosyl groups);GO:0005794(Golgi apparatus);GO:0005694(chromosome);GO:0005515(protein binding);GO:0000139(Golgi membrane);GO:0003950(NAD+ ADP-ribosyltransferase activity);GO:0016055(Wnt signaling pathway);GO:0000781(chromosome, telomeric region);GO:0005829(cytosol);GO:0016579(protein deubiquitination);GO:0000784(nuclear chromosome, telomeric region);GO:0019899(enzyme binding);GO:0032212(positive regulation of telomere maintenance via telomerase);GO:1904355(positive regulation of telomere capping);GO:0005635(nuclear envelope);GO:0000209(protein polyubiquitination);GO:0006471(protein ADP-ribosylation);GO:0070198(protein localization to chromosome, telomeric region);GO:0070213(protein auto-ADP-ribosylation);GO:1904357(negative regulation of telomere maintenance via telomere lengthening);GO:0000242(pericentriolar material);GO:0035264(multicellular organism growth);GO:0040014(regulation of multicellular organism growth)","NA","NA","NA","tankyrase 2 [Source:HGNC Symbol;Acc:HGNC:15677]",{"v":9.630726,"d":"9.63"},{"v":5.92556,"d":"5.93"},{"v":1.62528537387184,"d":"1.63"},{"v":0.700693054339855,"d":"0.70"},{"v":0.510980138906363,"d":"0.51"},{"v":0.91331108064651,"d":"0.91"},"up","no"]
["MSTRG.11085","TFG","ENST00000240851;ENST00000476228;ENST00000487505;ENST00000418917;ENST00000490574;ENST00000481203;ENST00000479672;ENST00000620299;ENST00000615993","GO:0005737(cytoplasm);GO:0006888(ER to Golgi vesicle-mediated transport);GO:0005783(endoplasmic reticulum);GO:0005515(protein binding);GO:0004871(signal transducer activity);GO:0007165(signal transduction);GO:0042802(identical protein binding);GO:0048208(COPII vesicle coating);GO:0000139(Golgi membrane);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0043123(positive regulation of I-kappaB kinase/NF-kappaB signaling);GO:0070971(endoplasmic reticulum exit site);GO:0070971(endoplasmic reticulum exit site)","05200(Pathways in cancer);05216(Thyroid cancer);05216(Thyroid cancer)","K09292","NA","TRK-fused gene [Source:HGNC Symbol;Acc:HGNC:11758]",{"v":2.66300677332799,"d":"2.66"},{"v":2.98388552503004,"d":"2.98"},{"v":0.892462780823732,"d":"0.89"},{"v":-0.164136090497084,"d":"-0.16"},{"v":0.511513065411373,"d":"0.51"},{"v":0.91331108064651,"d":"0.91"},"down","no"]
["ENSG00000162817","C1orf115","ENST00000294889","GO:0016020(membrane);GO:0016021(integral component of membrane)","NA","NA","NA","chromosome 1 open reading frame 115 [Source:HGNC Symbol;Acc:HGNC:25873]",{"v":0.69909,"d":"0.70"},{"v":0.785206,"d":"0.79"},{"v":0.890326869636758,"d":"0.89"},{"v":-0.167592998552153,"d":"-0.17"},{"v":0.512540805379766,"d":"0.51"},{"v":0.91331108064651,"d":"0.91"},"down","no"]
["ENSG00000104064","GABPB1","ENST00000220429;ENST00000380877;ENST00000359031;ENST00000560825;ENST00000615671;ENST00000429662;ENST00000396464;ENST00000543881;ENST00000558970;ENST00000558335;ENST00000559100;ENST00000561010","GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0005515(protein binding);GO:0000932(P-body);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0007005(mitochondrion organization);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0046982(protein heterodimerization activity);GO:0044212(transcription regulatory region DNA binding);GO:0044212(transcription regulatory region DNA binding)","NA","NA","NA","GA binding protein transcription factor beta subunit 1 [Source:HGNC Symbol;Acc:HGNC:4074]",{"v":0.885089551935869,"d":"0.89"},{"v":0.996148793621013,"d":"1.00"},{"v":0.888511392679158,"d":"0.89"},{"v":-0.170537819976854,"d":"-0.17"},{"v":0.514242178330012,"d":"0.51"},{"v":0.913404845654811,"d":"0.91"},"down","no"]
["ENSG00000075651","PLD1","ENST00000351298;ENST00000467432;ENST00000471075;ENST00000481505;ENST00000331659;ENST00000465816;ENST00000497307;ENST00000498278;ENST00000356327;ENST00000446289","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0016787(hydrolase activity);GO:0003824(catalytic activity);GO:0005794(Golgi apparatus);GO:0005765(lysosomal membrane);GO:0006629(lipid metabolic process);GO:0016042(lipid catabolic process);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005515(protein binding);GO:0000139(Golgi membrane);GO:0048471(perinuclear region of cytoplasm);GO:0035091(phosphatidylinositol binding);GO:0005886(plasma membrane);GO:0005768(endosome);GO:0031902(late endosome membrane);GO:0043312(neutrophil degranulation);GO:0035579(specific granule membrane);GO:0070821(tertiary granule membrane);GO:0016324(apical plasma membrane);GO:0006935(chemotaxis);GO:0007264(small GTPase mediated signal transduction);GO:0032534(regulation of microvillus assembly);GO:0007265(Ras protein signal transduction);GO:0004630(phospholipase D activity);GO:0070290(N-acylphosphatidylethanolamine-specific phospholipase D activity);GO:0006654(phosphatidic acid biosynthetic process);GO:0048870(cell motility);GO:0030139(endocytic vesicle);GO:0030139(endocytic vesicle)","00564(Glycerophospholipid metabolism);00565(Ether lipid metabolism);04014(Ras signaling pathway);04072(Phospholipase D signaling pathway);04071(Sphingolipid signaling pathway);04024(cAMP signaling pathway);04144(Endocytosis);04666(Fc gamma R-mediated phagocytosis);04912(GnRH signaling pathway);04724(Glutamatergic synapse);05200(Pathways in cancer);05231(Choline metabolism in cancer);05212(Pancreatic cancer);05212(Pancreatic cancer)","K01115","EC:3.1.4.4","phospholipase D1 [Source:HGNC Symbol;Acc:HGNC:9067]",{"v":0.571665337662338,"d":"0.57"},{"v":0.349737873551598,"d":"0.35"},{"v":1.63455370691501,"d":"1.63"},{"v":0.708896780853726,"d":"0.71"},{"v":0.51545611664613,"d":"0.52"},{"v":0.913404845654811,"d":"0.91"},"up","no"]
["MSTRG.9236","ITGA6","ENST00000409080;ENST00000264107;ENST00000409532;ENST00000412899;ENST00000475302;ENST00000469534;ENST00000497107;ENST00000470259;ENST00000416789","GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0030335(positive regulation of cell migration);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0046872(metal ion binding);GO:0007155(cell adhesion);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0007229(integrin-mediated signaling pathway);GO:0008305(integrin complex);GO:0005925(focal adhesion);GO:0050900(leukocyte migration);GO:0045296(cadherin binding);GO:0043547(positive regulation of GTPase activity);GO:0009986(cell surface);GO:0030198(extracellular matrix organization);GO:0042327(positive regulation of phosphorylation);GO:0031589(cell-substrate adhesion);GO:0072001(renal system development);GO:0043588(skin development);GO:0031581(hemidesmosome assembly);GO:2001237(negative regulation of extrinsic apoptotic signaling pathway);GO:0031994(insulin-like growth factor I binding);GO:0038132(neuregulin binding);GO:0043065(positive regulation of apoptotic process);GO:0048565(digestive tract development);GO:0010668(ectodermal cell differentiation);GO:0035878(nail development);GO:0097186(amelogenesis);GO:0007044(cell-substrate junction assembly);GO:0005178(integrin binding);GO:0032403(protein complex binding);GO:0043236(laminin binding);GO:0007160(cell-matrix adhesion);GO:0010811(positive regulation of cell-substrate adhesion);GO:0016337(single organismal cell-cell adhesion);GO:0022409(positive regulation of cell-cell adhesion);GO:0031668(cellular response to extracellular stimulus);GO:0033627(cell adhesion mediated by integrin);GO:0042475(odontogenesis of dentin-containing tooth);GO:0046847(filopodium assembly);GO:0050873(brown fat cell differentiation);GO:0071407(cellular response to organic cyclic compound);GO:0005604(basement membrane);GO:0005913(cell-cell adherens junction);GO:0009897(external side of plasma membrane);GO:0009925(basal plasma membrane);GO:0016323(basolateral plasma membrane);GO:0030056(hemidesmosome);GO:0030175(filopodium);GO:0034676(integrin alpha6-beta4 complex);GO:0045178(basal part of cell);GO:0045178(basal part of cell)","04151(PI3K-Akt signaling pathway);04512(ECM-receptor interaction);04514(Cell adhesion molecules (CAMs));04510(Focal adhesion);04810(Regulation of actin cytoskeleton);04640(Hematopoietic cell lineage);05200(Pathways in cancer);05222(Small cell lung cancer);05410(Hypertrophic cardiomyopathy (HCM));05412(Arrhythmogenic right ventricular cardiomyopathy (ARVC));05414(Dilated cardiomyopathy (DCM));05165(Human papillomavirus infection);05145(Toxoplasmosis);05145(Toxoplasmosis)","K06485","NA","integrin subunit alpha 6 [Source:HGNC Symbol;Acc:HGNC:6142]",{"v":8.54936145293127,"d":"8.55"},{"v":5.28080173228226,"d":"5.28"},{"v":1.61895141805227,"d":"1.62"},{"v":0.695059693493058,"d":"0.70"},{"v":0.515921183479527,"d":"0.52"},{"v":0.913404845654811,"d":"0.91"},"up","no"]
["ENSG00000167721","TSR1","ENST00000301364;ENST00000571806;ENST00000576112;ENST00000576202;ENST00000575049","GO:0005634(nucleus);GO:0003723(RNA binding);GO:0042254(ribosome biogenesis);GO:0005730(nucleolus);GO:0030688(preribosome, small subunit precursor);GO:0000462(maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA));GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0003924(GTPase activity);GO:0006364(rRNA processing);GO:0034511(U3 snoRNA binding);GO:0042255(ribosome assembly);GO:0005525(GTP binding);GO:0000479(endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA));GO:0000479(endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA))","NA","NA","NA","TSR1, ribosome maturation factor [Source:HGNC Symbol;Acc:HGNC:25542]",{"v":3.14296788674481,"d":"3.14"},{"v":1.93620215798016,"d":"1.94"},{"v":1.62326432381603,"d":"1.62"},{"v":0.698897939879295,"d":"0.70"},{"v":0.516556058231604,"d":"0.52"},{"v":0.913404845654811,"d":"0.91"},"up","no"]
["MSTRG.10044","ETS2","ENST00000360938;ENST00000456966;ENST00000360214;ENST00000432278","GO:0005634(nucleus);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0005886(plasma membrane);GO:0043565(sequence-specific DNA binding);GO:0005515(protein binding);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:0001078(transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0030154(cell differentiation);GO:0045893(positive regulation of transcription, DNA-templated);GO:0019904(protein domain specific binding);GO:0001501(skeletal system development);GO:0000977(RNA polymerase II regulatory region sequence-specific DNA binding);GO:0035259(glucocorticoid receptor binding);GO:0001712(ectodermal cell fate commitment);GO:0007498(mesoderm development);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0090009(primitive streak formation);GO:0090009(primitive streak formation)","04014(Ras signaling pathway);05166(HTLV-I infection);05166(HTLV-I infection)","K21932","NA","ETS proto-oncogene 2, transcription factor [Source:HGNC Symbol;Acc:HGNC:3489]",{"v":12.6879430959739,"d":"12.69"},{"v":7.85014062285093,"d":"7.85"},{"v":1.61626953013308,"d":"1.62"},{"v":0.692667802893017,"d":"0.69"},{"v":0.519211690814753,"d":"0.52"},{"v":0.915025544982428,"d":"0.92"},"up","no"]
["MSTRG.6468","TTC19;AC002553.3","ENST00000475723;ENST00000261647;ENST00000497842;ENST00000578103;ENST00000465567;ENST00000470399;ENST00000453002;ENST00000466729;ENST00000481107","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005739(mitochondrion);GO:0005743(mitochondrial inner membrane);GO:0051301(cell division);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0007049(cell cycle);GO:0005813(centrosome);GO:0005815(microtubule organizing center);GO:0030496(midbody);GO:0000910(cytokinesis);GO:0034551(mitochondrial respiratory chain complex III assembly);GO:0034551(mitochondrial respiratory chain complex III assembly)","NA","NA","NA","tetratricopeptide repeat domain 19 [Source:HGNC Symbol;Acc:HGNC:26006]",{"v":1.70172803167952,"d":"1.70"},{"v":1.9003132581294,"d":"1.90"},{"v":0.895498689176457,"d":"0.90"},{"v":-0.159236774479598,"d":"-0.16"},{"v":0.519293940503392,"d":"0.52"},{"v":0.915025544982428,"d":"0.92"},"down","no"]
["ENSG00000075336","TIMM21","ENST00000169551;ENST00000577952;ENST00000579071;ENST00000584925;ENST00000580087;ENST00000581467","GO:0003674(molecular_function);GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0015031(protein transport);GO:0005739(mitochondrion);GO:0005744(mitochondrial inner membrane presequence translocase complex);GO:0005515(protein binding);GO:0030150(protein import into mitochondrial matrix);GO:0031966(mitochondrial membrane);GO:0032981(mitochondrial respiratory chain complex I assembly);GO:0033617(mitochondrial respiratory chain complex IV assembly);GO:0033617(mitochondrial respiratory chain complex IV assembly)","NA","NA","NA","translocase of inner mitochondrial membrane 21 [Source:HGNC Symbol;Acc:HGNC:25010]",{"v":0.997146596390169,"d":"1.00"},{"v":1.10929466129032,"d":"1.11"},{"v":0.898901465216013,"d":"0.90"},{"v":-0.153765114225792,"d":"-0.15"},{"v":0.521612591587048,"d":"0.52"},{"v":0.915038172142077,"d":"0.92"},"down","no"]
["MSTRG.11782","HADH","ENST00000309522;ENST00000505878;ENST00000626637;ENST00000639698;ENST00000638648;ENST00000638559;ENST00000639146;ENST00000510728;ENST00000640586;ENST00000640752;ENST00000638621;ENST00000514776;ENST00000603302","GO:0005654(nucleoplasm);GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0005739(mitochondrion);GO:0003857(3-hydroxyacyl-CoA dehydrogenase activity);GO:0006631(fatty acid metabolic process);GO:0006629(lipid metabolic process);GO:0070403(NAD+ binding);GO:0005759(mitochondrial matrix);GO:0005737(cytoplasm);GO:0006635(fatty acid beta-oxidation);GO:0009725(response to hormone);GO:0014823(response to activity);GO:0032868(response to insulin);GO:0042493(response to drug);GO:0046676(negative regulation of insulin secretion);GO:0005743(mitochondrial inner membrane);GO:0005743(mitochondrial inner membrane)","00650(Butanoate metabolism);00062(Fatty acid elongation);00071(Fatty acid degradation);00280(Valine, leucine and isoleucine degradation);00310(Lysine degradation);00380(Tryptophan metabolism);00380(Tryptophan metabolism)","K00022","EC:1.1.1.35","hydroxyacyl-CoA dehydrogenase [Source:HGNC Symbol;Acc:HGNC:4799]",{"v":0.896065002730432,"d":"0.90"},{"v":0.995592397153731,"d":"1.00"},{"v":0.90003198627487,"d":"0.90"},{"v":-0.151951820533803,"d":"-0.15"},{"v":0.522000022946403,"d":"0.52"},{"v":0.915038172142077,"d":"0.92"},"down","no"]
["MSTRG.6303","TRPV1;SHPK;AC027796.3","ENST00000572705;ENST00000225519;ENST00000570742;ENST00000399756;ENST00000571088;ENST00000399759;ENST00000572919","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0055085(transmembrane transport);GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0005216(ion channel activity);GO:0006811(ion transport);GO:0005886(plasma membrane);GO:0042995(cell projection);GO:0006816(calcium ion transport);GO:0065009(regulation of molecular function);GO:0030054(cell junction);GO:0045202(synapse);GO:0045211(postsynaptic membrane);GO:0005262(calcium channel activity);GO:0070588(calcium ion transmembrane transport);GO:0060079(excitatory postsynaptic potential);GO:0051209(release of sequestered calcium ion into cytosol);GO:0005516(calmodulin binding);GO:0005887(integral component of plasma membrane);GO:0035091(phosphatidylinositol binding);GO:0032591(dendritic spine membrane);GO:0004888(transmembrane signaling receptor activity);GO:0031226(intrinsic component of plasma membrane);GO:0007166(cell surface receptor signaling pathway);GO:0051289(protein homotetramerization);GO:0051219(phosphoprotein binding);GO:0034605(cellular response to heat);GO:0015278(calcium-release channel activity);GO:0071318(cellular response to ATP);GO:0098703(calcium ion import across plasma membrane);GO:0071468(cellular response to acidic pH);GO:0071312(cellular response to alkaloid);GO:0007635(chemosensory behavior);GO:0005230(extracellular ligand-gated ion channel activity);GO:0005231(excitatory extracellular ligand-gated ion channel activity);GO:0050955(thermoception);GO:1901594(response to capsazepine);GO:0005261(cation channel activity);GO:0008324(cation transmembrane transporter activity);GO:0015276(ligand-gated ion channel activity);GO:0017081(chloride channel regulator activity);GO:0042802(identical protein binding);GO:0097603(temperature-gated ion channel activity);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0001659(temperature homeostasis);GO:0001660(fever generation);GO:0001774(microglial cell activation);GO:0002024(diet induced thermogenesis);GO:0002790(peptide secretion);GO:0006629(lipid metabolic process);GO:0006954(inflammatory response);GO:0007204(positive regulation of cytosolic calcium ion concentration);GO:0009268(response to pH);GO:0009408(response to heat);GO:0010243(response to organonitrogen compound);GO:0014047(glutamate secretion);GO:0014832(urinary bladder smooth muscle contraction);GO:0019233(sensory perception of pain);GO:0034220(ion transmembrane transport);GO:0043065(positive regulation of apoptotic process);GO:0043434(response to peptide hormone);GO:0045429(positive regulation of nitric oxide biosynthetic process);GO:0048265(response to pain);GO:0048266(behavioral response to pain);GO:0050954(sensory perception of mechanical stimulus);GO:0050960(detection of temperature stimulus involved in thermoception);GO:0050965(detection of temperature stimulus involved in sensory perception of pain);GO:0050968(detection of chemical stimulus involved in sensory perception of pain);GO:0060083(smooth muscle contraction involved in micturition);GO:0060454(positive regulation of gastric acid secretion);GO:0071345(cellular response to cytokine stimulus);GO:0071356(cellular response to tumor necrosis factor);GO:0071363(cellular response to growth factor stimulus);GO:0071502(cellular response to temperature stimulus);GO:0090212(negative regulation of establishment of blood-brain barrier);GO:1990090(cellular response to nerve growth factor stimulus);GO:0005829(cytosol);GO:0009897(external side of plasma membrane);GO:0030425(dendrite);GO:0043005(neuron projection);GO:0043025(neuronal cell body);GO:0005737(cytoplasm);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0016773(phosphotransferase activity, alcohol group as acceptor);GO:0005975(carbohydrate metabolic process);GO:0071222(cellular response to lipopolysaccharide);GO:0050727(regulation of inflammatory response);GO:0006098(pentose-phosphate shunt);GO:0043030(regulation of macrophage activation);GO:0035963(cellular response to interleukin-13);GO:0071353(cellular response to interleukin-4);GO:0009052(pentose-phosphate shunt, non-oxidative branch);GO:0050277(sedoheptulokinase activity);GO:0005975(carbohydrate metabolic process)","04080(Neuroactive ligand-receptor interaction);04750(Inflammatory mediator regulation of TRP channels);04750(Inflammatory mediator regulation of TRP channels)","K05222","NA","transient receptor potential cation channel subfamily V member 1 [Source:HGNC Symbol;Acc:HGNC:12716];sedoheptulokinase [Source:HGNC Symbol;Acc:HGNC:1492]",{"v":0.700840612357173,"d":"0.70"},{"v":0.781539714663563,"d":"0.78"},{"v":0.89674344017037,"d":"0.90"},{"v":-0.157232808223705,"d":"-0.16"},{"v":0.523298706122863,"d":"0.52"},{"v":0.915038172142077,"d":"0.92"},"down","no"]
["MSTRG.13507","AHR","ENST00000242057;ENST00000492120;ENST00000475440;ENST00000481944","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0046983(protein dimerization activity);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0005515(protein binding);GO:0030522(intracellular receptor signaling pathway);GO:0007049(cell cycle);GO:0048511(rhythmic process);GO:0006915(apoptotic process);GO:0045893(positive regulation of transcription, DNA-templated);GO:0004874(aryl hydrocarbon receptor activity);GO:0009410(response to xenobiotic stimulus);GO:0034751(aryl hydrocarbon receptor complex);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0006366(transcription from RNA polymerase II promoter);GO:0006805(xenobiotic metabolic process);GO:0045892(negative regulation of transcription, DNA-templated);GO:0043234(protein complex);GO:0051879(Hsp90 protein binding);GO:0070888(E-box binding);GO:0032922(circadian regulation of gene expression);GO:0004879(RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding);GO:0009636(response to toxic substance);GO:0008134(transcription factor binding);GO:0017025(TBP-class protein binding);GO:0001568(blood vessel development);GO:0035326(enhancer binding);GO:0001223(transcription coactivator binding);GO:0001094(TFIID-class transcription factor binding);GO:0044212(transcription regulatory region DNA binding);GO:0046982(protein heterodimerization activity);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0010468(regulation of gene expression);GO:0030888(regulation of B cell proliferation);GO:0005667(transcription factor complex);GO:0034752(cytosolic aryl hydrocarbon receptor complex);GO:0034753(nuclear aryl hydrocarbon receptor complex);GO:0034753(nuclear aryl hydrocarbon receptor complex)","04659(Th17 cell differentiation);04659(Th17 cell differentiation)","K09093","NA","aryl hydrocarbon receptor [Source:HGNC Symbol;Acc:HGNC:348]",{"v":6.23241500046414,"d":"6.23"},{"v":3.87235453701555,"d":"3.87"},{"v":1.60946394264496,"d":"1.61"},{"v":0.686580256001668,"d":"0.69"},{"v":0.524791813161104,"d":"0.52"},{"v":0.915038172142077,"d":"0.92"},"up","no"]
["ENSG00000143545","RAB13","ENST00000368575;ENST00000495720;ENST00000462680","GO:0006810(transport);GO:0016020(membrane);GO:0015031(protein transport);GO:0005525(GTP binding);GO:0000166(nucleotide binding);GO:0005829(cytosol);GO:0003924(GTPase activity);GO:0005886(plasma membrane);GO:0042995(cell projection);GO:0005515(protein binding);GO:0030054(cell junction);GO:0030659(cytoplasmic vesicle membrane);GO:0031410(cytoplasmic vesicle);GO:0005923(bicellular tight junction);GO:0005768(endosome);GO:0030027(lamellipodium);GO:0070062(extracellular exosome);GO:0061024(membrane organization);GO:0005802(trans-Golgi network);GO:0043687(post-translational protein modification);GO:0016197(endosomal transport);GO:0055037(recycling endosome);GO:0055038(recycling endosome membrane);GO:0016328(lateral plasma membrane);GO:0043005(neuron projection);GO:0032869(cellular response to insulin stimulus);GO:0031175(neuron projection development);GO:0090002(establishment of protein localization to plasma membrane);GO:0030866(cortical actin cytoskeleton organization);GO:0030139(endocytic vesicle);GO:0070830(bicellular tight junction assembly);GO:0032456(endocytic recycling);GO:0035767(endothelial cell chemotaxis);GO:0010737(protein kinase A signaling);GO:0032593(insulin-responsive compartment);GO:0034236(protein kinase A catalytic subunit binding);GO:0044795(trans-Golgi network to recycling endosome transport);GO:0072659(protein localization to plasma membrane);GO:0097368(establishment of Sertoli cell barrier);GO:1902463(protein localization to cell leading edge);GO:0005911(cell-cell junction);GO:0005911(cell-cell junction)","04530(Tight junction);04530(Tight junction)","K06109","NA","RAB13, member RAS oncogene family [Source:HGNC Symbol;Acc:HGNC:9762]",{"v":1.00502817557252,"d":"1.01"},{"v":1.12075942966194,"d":"1.12"},{"v":0.896738540826439,"d":"0.90"},{"v":-0.157240690387304,"d":"-0.16"},{"v":0.524955762647808,"d":"0.52"},{"v":0.915038172142077,"d":"0.92"},"down","no"]
["MSTRG.2965","ETS1","ENST00000319397;ENST00000526145;ENST00000392668;ENST00000530924;ENST00000608978;ENST00000531611;ENST00000535549","GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0005634(nucleus);GO:0050729(positive regulation of inflammatory response);GO:1904996(positive regulation of leukocyte adhesion to vascular endothelial cell);GO:0005737(cytoplasm);GO:0005654(nucleoplasm);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0043565(sequence-specific DNA binding);GO:0005515(protein binding);GO:0002376(immune system process);GO:0042802(identical protein binding);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:0006955(immune response);GO:0008134(transcription factor binding);GO:0045893(positive regulation of transcription, DNA-templated);GO:0000982(transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0001077(transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0008285(negative regulation of cell proliferation);GO:0010595(positive regulation of endothelial cell migration);GO:0045765(regulation of angiogenesis);GO:0048870(cell motility);GO:0035035(histone acetyltransferase binding);GO:1990837(sequence-specific double-stranded DNA binding);GO:0001666(response to hypoxia);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0007565(female pregnancy);GO:0008284(positive regulation of cell proliferation);GO:0009611(response to wounding);GO:0009612(response to mechanical stimulus);GO:0010715(regulation of extracellular matrix disassembly);GO:0021854(hypothalamus development);GO:0021983(pituitary gland development);GO:0030335(positive regulation of cell migration);GO:0030578(PML body organization);GO:0032355(response to estradiol);GO:0034616(response to laminar fluid shear stress);GO:0044849(estrous cycle);GO:0045648(positive regulation of erythrocyte differentiation);GO:0045766(positive regulation of angiogenesis);GO:0050728(negative regulation of inflammatory response);GO:0051272(positive regulation of cellular component movement);GO:0060055(angiogenesis involved in wound healing);GO:0061614(pri-miRNA transcription from RNA polymerase II promoter);GO:0070301(cellular response to hydrogen peroxide);GO:0070555(response to interleukin-1);GO:0005667(transcription factor complex);GO:0005667(transcription factor complex)","04014(Ras signaling pathway);04218(Cellular senescence);05200(Pathways in cancer);05211(Renal cell carcinoma);05166(HTLV-I infection);05166(HTLV-I infection)","K02678","NA","ETS proto-oncogene 1, transcription factor [Source:HGNC Symbol;Acc:HGNC:3488]",{"v":18.4223243434047,"d":"18.42"},{"v":11.4640276283396,"d":"11.46"},{"v":1.60696789476186,"d":"1.61"},{"v":0.684341106031964,"d":"0.68"},{"v":0.526586348777837,"d":"0.53"},{"v":0.915555573488818,"d":"0.92"},"up","no"]
["MSTRG.2913","ARCN1","ENST00000264028;ENST00000359415;ENST00000392859","GO:0003723(RNA binding);GO:0006810(transport);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0015031(protein transport);GO:0005794(Golgi apparatus);GO:0000139(Golgi membrane);GO:0006890(retrograde vesicle-mediated transport, Golgi to ER);GO:0031410(cytoplasmic vesicle);GO:0016192(vesicle-mediated transport);GO:0030126(COPI vesicle coat);GO:0030663(COPI-coated vesicle membrane);GO:0005789(endoplasmic reticulum membrane);GO:0005829(cytosol);GO:0006886(intracellular protein transport);GO:0006888(ER to Golgi vesicle-mediated transport);GO:0030133(transport vesicle);GO:0008344(adult locomotory behavior);GO:0021691(cerebellar Purkinje cell layer maturation);GO:0043473(pigmentation);GO:0048193(Golgi vesicle transport);GO:0005783(endoplasmic reticulum);GO:0030137(COPI-coated vesicle);GO:0030137(COPI-coated vesicle)","NA","NA","NA","archain 1 [Source:HGNC Symbol;Acc:HGNC:649]",{"v":10.7862466598037,"d":"10.79"},{"v":6.71221966890113,"d":"6.71"},{"v":1.60695674335246,"d":"1.61"},{"v":0.684331094544546,"d":"0.68"},{"v":0.527399105415535,"d":"0.53"},{"v":0.916068367845465,"d":"0.92"},"up","no"]
["MSTRG.4101","ANKRD10","ENST00000310847;MSTRG.4101.9;ENST00000267339;ENST00000464579;ENST00000465753;ENST00000463156;ENST00000475809;ENST00000460846;ENST00000494859;ENST00000485844;ENST00000603993;ENST00000489973","GO:0005515(protein binding);GO:0060828(regulation of canonical Wnt signaling pathway);GO:0060828(regulation of canonical Wnt signaling pathway)","NA","NA","NA","ankyrin repeat domain 10 [Source:HGNC Symbol;Acc:HGNC:20265]",{"v":6.5934862767944,"d":"6.59"},{"v":7.28707320404591,"d":"7.29"},{"v":0.904819547185773,"d":"0.90"},{"v":-0.144297998093492,"d":"-0.14"},{"v":0.528757441594894,"d":"0.53"},{"v":0.916349823793689,"d":"0.92"},"down","no"]
["ENSG00000168758","SEMA4C","ENST00000305476;ENST00000474420;ENST00000482925;ENST00000449330;ENST00000442264;ENST00000467747","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0007275(multicellular organism development);GO:0005615(extracellular space);GO:0030054(cell junction);GO:0045202(synapse);GO:0045211(postsynaptic membrane);GO:0007399(nervous system development);GO:0030154(cell differentiation);GO:0031410(cytoplasmic vesicle);GO:0014069(postsynaptic density);GO:0030672(synaptic vesicle membrane);GO:0032874(positive regulation of stress-activated MAPK cascade);GO:0001843(neural tube closure);GO:0071526(semaphorin-plexin signaling pathway);GO:0050919(negative chemotaxis);GO:0042692(muscle cell differentiation);GO:0021535(cell migration in hindbrain);GO:0021549(cerebellum development);GO:0021549(cerebellum development)","04360(Axon guidance);04360(Axon guidance)","K06521","NA","semaphorin 4C [Source:HGNC Symbol;Acc:HGNC:10731]",{"v":3.07193290076336,"d":"3.07"},{"v":1.91323210800715,"d":"1.91"},{"v":1.60562478954168,"d":"1.61"},{"v":0.683134796023905,"d":"0.68"},{"v":0.529474391026273,"d":"0.53"},{"v":0.916491973915226,"d":"0.92"},"up","no"]
["ENSG00000163611","SPICE1","ENST00000295872;ENST00000496105;ENST00000480527;ENST00000495812","GO:0005737(cytoplasm);GO:0051301(cell division);GO:0005813(centrosome);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0007049(cell cycle);GO:0005819(spindle);GO:0005814(centriole);GO:0090307(mitotic spindle assembly);GO:0051310(metaphase plate congression);GO:0046599(regulation of centriole replication);GO:0046599(regulation of centriole replication)","NA","NA","NA","spindle and centriole associated protein 1 [Source:HGNC Symbol;Acc:HGNC:25083]",{"v":0.514667182722579,"d":"0.51"},{"v":0.571767585946354,"d":"0.57"},{"v":0.900133542671423,"d":"0.90"},{"v":-0.151789041158822,"d":"-0.15"},{"v":0.53138278687365,"d":"0.53"},{"v":0.917067662946009,"d":"0.92"},"down","no"]
["MSTRG.11025","THOC7","ENST00000295899;ENST00000464327;ENST00000487570;ENST00000473141;ENST00000469153;ENST00000469584;ENST00000498422","GO:0003723(RNA binding);GO:0006397(mRNA processing);GO:0006810(transport);GO:0008380(RNA splicing);GO:0051028(mRNA transport);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016607(nuclear speck);GO:0005829(cytosol);GO:0005515(protein binding);GO:0000445(THO complex part of transcription export complex);GO:0006406(mRNA export from nucleus);GO:0005654(nucleoplasm);GO:0000784(nuclear chromosome, telomeric region);GO:0006369(termination of RNA polymerase II transcription);GO:0006405(RNA export from nucleus);GO:0031124(mRNA 3'-end processing);GO:0000346(transcription export complex);GO:0046784(viral mRNA export from host cell nucleus);GO:0000347(THO complex);GO:0000347(THO complex)","03013(RNA transport);03013(RNA transport)","K13176","NA","THO complex 7 [Source:HGNC Symbol;Acc:HGNC:29874]",{"v":9.41364818721973,"d":"9.41"},{"v":10.3897055375561,"d":"10.39"},{"v":0.906055340374357,"d":"0.91"},{"v":-0.142328924477475,"d":"-0.14"},{"v":0.533085521684549,"d":"0.53"},{"v":0.917786949683637,"d":"0.92"},"down","no"]
["MSTRG.12152","F2R","ENST00000319211;ENST00000505600","GO:0008285(negative regulation of cell proliferation);GO:0046427(positive regulation of JAK-STAT cascade);GO:0006919(activation of cysteine-type endopeptidase activity involved in apoptotic process);GO:0030335(positive regulation of cell migration);GO:0005623(cell);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0004930(G-protein coupled receptor activity);GO:0007186(G-protein coupled receptor signaling pathway);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0004871(signal transducer activity);GO:0007165(signal transduction);GO:0045211(postsynaptic membrane);GO:0007596(blood coagulation);GO:0001965(G-protein alpha-subunit binding);GO:0015057(thrombin-activated receptor activity);GO:0031681(G-protein beta-subunit binding);GO:0006954(inflammatory response);GO:0007204(positive regulation of cytosolic calcium ion concentration);GO:0014068(positive regulation of phosphatidylinositol 3-kinase signaling);GO:0030194(positive regulation of blood coagulation);GO:0032496(response to lipopolysaccharide);GO:0032651(regulation of interleukin-1 beta production);GO:0035025(positive regulation of Rho protein signal transduction);GO:0045907(positive regulation of vasoconstriction);GO:0048873(homeostasis of number of cells within a tissue);GO:0070374(positive regulation of ERK1 and ERK2 cascade);GO:0070493(thrombin-activated receptor signaling pathway);GO:0099553(trans-synaptic signaling by endocannabinoid, modulating synaptic transmission);GO:1900134(negative regulation of renin secretion into blood stream);GO:0005576(extracellular region);GO:0005769(early endosome);GO:0005770(late endosome);GO:0005887(integral component of plasma membrane);GO:0043123(positive regulation of I-kappaB kinase/NF-kappaB signaling);GO:0008284(positive regulation of cell proliferation);GO:0043524(negative regulation of neuron apoptotic process);GO:2000484(positive regulation of interleukin-8 secretion);GO:2000778(positive regulation of interleukin-6 secretion);GO:0005794(Golgi apparatus);GO:0009986(cell surface);GO:0045893(positive regulation of transcription, DNA-templated);GO:0007599(hemostasis);GO:0030168(platelet activation);GO:0051482(positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway);GO:0009653(anatomical structure morphogenesis);GO:0005102(receptor binding);GO:0007205(protein kinase C-activating G-protein coupled receptor signaling pathway);GO:0051928(positive regulation of calcium ion transport);GO:0031594(neuromuscular junction);GO:0051281(positive regulation of release of sequestered calcium ion into cytosol);GO:0000186(activation of MAPKK activity);GO:0007260(tyrosine phosphorylation of STAT protein);GO:0007262(STAT protein import into nucleus);GO:0005901(caveola);GO:0051209(release of sequestered calcium ion into cytosol);GO:0060155(platelet dense granule organization);GO:0009611(response to wounding);GO:0032967(positive regulation of collagen biosynthetic process);GO:0007200(phospholipase C-activating G-protein coupled receptor signaling pathway);GO:0043410(positive regulation of MAPK cascade);GO:0002248(connective tissue replacement involved in inflammatory response wound healing);GO:0051930(regulation of sensory perception of pain);GO:0003105(negative regulation of glomerular filtration);GO:0007529(establishment of synaptic specificity at neuromuscular junction);GO:0030193(regulation of blood coagulation);GO:0043280(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process);GO:0045987(positive regulation of smooth muscle contraction);GO:0031094(platelet dense tubular network);GO:0031094(platelet dense tubular network)","04015(Rap1 signaling pathway);04020(Calcium signaling pathway);04072(Phospholipase D signaling pathway);04024(cAMP signaling pathway);04151(PI3K-Akt signaling pathway);04080(Neuroactive ligand-receptor interaction);04810(Regulation of actin cytoskeleton);04610(Complement and coagulation cascades);04611(Platelet activation);05200(Pathways in cancer);05200(Pathways in cancer)","K03914","NA","coagulation factor II thrombin receptor [Source:HGNC Symbol;Acc:HGNC:3537]",{"v":9.49977846974914,"d":"9.50"},{"v":5.93861116847024,"d":"5.94"},{"v":1.59966332198783,"d":"1.60"},{"v":0.677768295856634,"d":"0.68"},{"v":0.534398852639956,"d":"0.53"},{"v":0.918107269553244,"d":"0.92"},"up","no"]
["MSTRG.3733","TRAFD1","ENST00000257604;ENST00000412615;ENST00000549358;ENST00000547063;ENST00000548277;ENST00000552890;ENST00000550051;ENST00000548092","GO:0046872(metal ion binding);GO:0005515(protein binding);GO:0045824(negative regulation of innate immune response);GO:0034097(response to cytokine);GO:0034097(response to cytokine)","NA","NA","NA","TRAF-type zinc finger domain containing 1 [Source:HGNC Symbol;Acc:HGNC:24808]",{"v":14.5909658444162,"d":"14.59"},{"v":16.0417265967005,"d":"16.04"},{"v":0.909563303953659,"d":"0.91"},{"v":-0.136754044562225,"d":"-0.14"},{"v":0.535151198822014,"d":"0.54"},{"v":0.918113587224118,"d":"0.92"},"down","no"]
["ENSG00000138161","CUZD1","ENST00000368904;ENST00000368899;ENST00000368900","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0007155(cell adhesion);GO:0051301(cell division);GO:0007049(cell cycle);GO:0031410(cytoplasmic vesicle);GO:0008283(cell proliferation);GO:0030658(transport vesicle membrane);GO:0006931(substrate-dependent cell migration, cell attachment to substrate);GO:0032023(trypsinogen activation);GO:0042589(zymogen granule membrane);GO:0042589(zymogen granule membrane)","NA","NA","NA","CUB and zona pellucida like domains 1 [Source:HGNC Symbol;Acc:HGNC:17937]",{"v":0.326606442551963,"d":"0.33"},{"v":0.366408426096998,"d":"0.37"},{"v":0.891372630348576,"d":"0.89"},{"v":-0.165899431296661,"d":"-0.17"},{"v":0.535895737724172,"d":"0.54"},{"v":0.918295693288604,"d":"0.92"},"down","no"]
["MSTRG.15289","TFE3","ENST00000493583;ENST00000315869;ENST00000481606;ENST00000487451;ENST00000495940","GO:0005634(nucleus);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0046983(protein dimerization activity);GO:0006355(regulation of transcription, DNA-templated);GO:0006366(transcription from RNA polymerase II promoter);GO:0006959(humoral immune response);GO:0045670(regulation of osteoclast differentiation);GO:0045893(positive regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0002376(immune system process);GO:0002250(adaptive immune response);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0045785(positive regulation of cell adhesion);GO:0044212(transcription regulatory region DNA binding);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:0001077(transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0001077(transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding)","04137(Mitophagy - animal);05202(Transcriptional misregulation in cancers);05211(Renal cell carcinoma);05211(Renal cell carcinoma)","K09105","NA","transcription factor binding to IGHM enhancer 3 [Source:HGNC Symbol;Acc:HGNC:11752]",{"v":12.4183167235583,"d":"12.42"},{"v":7.78588631099697,"d":"7.79"},{"v":1.59497791613247,"d":"1.59"},{"v":0.673536448750816,"d":"0.67"},{"v":0.538454924086951,"d":"0.54"},{"v":0.920063018442182,"d":"0.92"},"up","no"]
["ENSG00000168781","PPIP5K1","ENST00000472547;ENST00000437065;ENST00000465123;ENST00000334933;ENST00000427877;ENST00000396923;ENST00000420765;ENST00000469229;ENST00000360301;ENST00000439195;ENST00000381885;ENST00000462136;ENST00000453080;ENST00000432870;ENST00000476294;ENST00000360135","GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0016311(dephosphorylation);GO:0016310(phosphorylation);GO:0003993(acid phosphatase activity);GO:0000827(inositol-1,3,4,5,6-pentakisphosphate kinase activity);GO:0000832(inositol hexakisphosphate 5-kinase activity);GO:0033857(diphosphoinositol-pentakisphosphate kinase activity);GO:0006020(inositol metabolic process);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0005886(plasma membrane);GO:0043647(inositol phosphate metabolic process);GO:0000828(inositol hexakisphosphate kinase activity);GO:0000829(inositol heptakisphosphate kinase activity);GO:0052723(inositol hexakisphosphate 1-kinase activity);GO:0052724(inositol hexakisphosphate 3-kinase activity);GO:0032958(inositol phosphate biosynthetic process);GO:0032958(inositol phosphate biosynthetic process)","04070(Phosphatidylinositol signaling system);04070(Phosphatidylinositol signaling system)","K13024","EC:2.7.4.24","diphosphoinositol pentakisphosphate kinase 1 [Source:HGNC Symbol;Acc:HGNC:29023]",{"v":0.887921779690402,"d":"0.89"},{"v":0.54895334006192,"d":"0.55"},{"v":1.61748133200218,"d":"1.62"},{"v":0.69374906159442,"d":"0.69"},{"v":0.539411987363336,"d":"0.54"},{"v":0.920063018442182,"d":"0.92"},"up","no"]
["ENSG00000155324","GRAMD2B","ENST00000285689;ENST00000542322;ENST00000508523;ENST00000515200;ENST00000514932","GO:0005515(protein binding);GO:0042802(identical protein binding);GO:0005881(cytoplasmic microtubule);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016021(integral component of membrane)","NA","NA","NA","GRAM domain containing 2B [Source:HGNC Symbol;Acc:HGNC:24911]",{"v":0.488236872104534,"d":"0.49"},{"v":0.546758443278559,"d":"0.55"},{"v":0.892966314661537,"d":"0.89"},{"v":-0.163322341251238,"d":"-0.16"},{"v":0.540827201691439,"d":"0.54"},{"v":0.920912946223267,"d":"0.92"},"down","no"]
["MSTRG.7609","DAZAP1","ENST00000585485;ENST00000589484;ENST00000233078;ENST00000592522;ENST00000336761;ENST00000587079;ENST00000586579;ENST00000589874;ENST00000590419;ENST00000587833","GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0007275(multicellular organism development);GO:0030154(cell differentiation);GO:0007283(spermatogenesis);GO:0035613(RNA stem-loop binding);GO:0001893(maternal placenta development);GO:0008283(cell proliferation);GO:0048026(positive regulation of mRNA splicing, via spliceosome);GO:0048026(positive regulation of mRNA splicing, via spliceosome)","03015(mRNA surveillance pathway);03015(mRNA surveillance pathway)","K14411","NA","DAZ associated protein 1 [Source:HGNC Symbol;Acc:HGNC:2683]",{"v":3.81926145364634,"d":"3.82"},{"v":2.39933759906532,"d":"2.40"},{"v":1.5917982759634,"d":"1.59"},{"v":0.670657518854605,"d":"0.67"},{"v":0.542602217379219,"d":"0.54"},{"v":0.921772900881344,"d":"0.92"},"up","no"]
["ENSG00000171714","ANO5","ENST00000324559;ENST00000532043","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0046983(protein dimerization activity);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005886(plasma membrane);GO:0006821(chloride transport);GO:1902476(chloride transmembrane transport);GO:0005229(intracellular calcium activated chloride channel activity);GO:0034220(ion transmembrane transport);GO:0005622(intracellular);GO:0031982(vesicle);GO:0031982(vesicle)","NA","NA","NA","anoctamin 5 [Source:HGNC Symbol;Acc:HGNC:27337]",{"v":0.16926505826087,"d":"0.17"},{"v":0.188313591304348,"d":"0.19"},{"v":0.898846743288474,"d":"0.90"},{"v":-0.153852943047579,"d":"-0.15"},{"v":0.543978805180974,"d":"0.54"},{"v":0.923088853461744,"d":"0.92"},"down","no"]
["ENSG00000188681","TEKT4P2","ENST00000416067;ENST00000559466","NA","NA","NA","NA","tektin 4 pseudogene 2 [Source:HGNC Symbol;Acc:HGNC:40046]",{"v":0.408404444781291,"d":"0.41"},{"v":0.464616669987007,"d":"0.46"},{"v":0.879013757282346,"d":"0.88"},{"v":-0.186042349987737,"d":"-0.19"},{"v":0.547616033222016,"d":"0.55"},{"v":0.925824084150821,"d":"0.93"},"down","no"]
["MSTRG.12002","IL7R","ENST00000514217;MSTRG.12002.8;ENST00000303115;ENST00000505875;MSTRG.12002.5;ENST00000506850;ENST00000505093;ENST00000511031;ENST00000511982;ENST00000515665;ENST00000508941;ENST00000509668","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0004896(cytokine receptor activity);GO:0006955(immune response);GO:0007165(signal transduction);GO:0007166(cell surface receptor signaling pathway);GO:0038111(interleukin-7-mediated signaling pathway);GO:0003823(antigen binding);GO:0004917(interleukin-7 receptor activity);GO:0000018(regulation of DNA recombination);GO:0000902(cell morphogenesis);GO:0001915(negative regulation of T cell mediated cytotoxicity);GO:0002377(immunoglobulin production);GO:0008361(regulation of cell size);GO:0010628(positive regulation of gene expression);GO:0016049(cell growth);GO:0030217(T cell differentiation);GO:0033089(positive regulation of T cell differentiation in thymus);GO:0042100(B cell proliferation);GO:0048535(lymph node development);GO:0048872(homeostasis of number of cells);GO:0009897(external side of plasma membrane);GO:0019221(cytokine-mediated signaling pathway);GO:0019221(cytokine-mediated signaling pathway)","04630(Jak-STAT signaling pathway);04068(FoxO signaling pathway);04151(PI3K-Akt signaling pathway);04060(Cytokine-cytokine receptor interaction);04640(Hematopoietic cell lineage);05200(Pathways in cancer);05340(Primary immunodeficiency);05340(Primary immunodeficiency)","K05072","NA","interleukin 7 receptor [Source:HGNC Symbol;Acc:HGNC:6024]",{"v":90.4004733893281,"d":"90.40"},{"v":57.138240060112,"d":"57.14"},{"v":1.58213611924733,"d":"1.58"},{"v":0.661873727569952,"d":"0.66"},{"v":0.548727202593036,"d":"0.55"},{"v":0.925994420118579,"d":"0.93"},"up","no"]
["MSTRG.3580","DUSP6","ENST00000279488;ENST00000547291;ENST00000547140;MSTRG.3580.2;ENST00000548755;ENST00000308385","GO:0005737(cytoplasm);GO:0016787(hydrolase activity);GO:0008138(protein tyrosine/serine/threonine phosphatase activity);GO:0016791(phosphatase activity);GO:0006470(protein dephosphorylation);GO:0016311(dephosphorylation);GO:0035335(peptidyl-tyrosine dephosphorylation);GO:0004721(phosphoprotein phosphatase activity);GO:0017017(MAP kinase tyrosine/serine/threonine phosphatase activity);GO:0000188(inactivation of MAPK activity);GO:0004725(protein tyrosine phosphatase activity);GO:0001933(negative regulation of protein phosphorylation);GO:0010033(response to organic substance);GO:0010942(positive regulation of cell death);GO:0014070(response to organic cyclic compound);GO:0030154(cell differentiation);GO:0042493(response to drug);GO:0060420(regulation of heart growth);GO:0070373(negative regulation of ERK1 and ERK2 cascade);GO:0070848(response to growth factor);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0000165(MAPK cascade);GO:0043065(positive regulation of apoptotic process);GO:0000187(activation of MAPK activity);GO:0009953(dorsal/ventral pattern formation);GO:0040036(regulation of fibroblast growth factor receptor signaling pathway);GO:0042663(regulation of endodermal cell fate specification);GO:0051409(response to nitrosative stress);GO:0051409(response to nitrosative stress)","04010(MAPK signaling pathway);05202(Transcriptional misregulation in cancers);05221(Acute myeloid leukemia);05221(Acute myeloid leukemia)","K21946","EC:3.1.3.16;EC:3.1.3.48","dual specificity phosphatase 6 [Source:HGNC Symbol;Acc:HGNC:3072]",{"v":28.9838354383174,"d":"28.98"},{"v":31.5504390683987,"d":"31.55"},{"v":0.918650779327758,"d":"0.92"},{"v":-0.12241156273329,"d":"-0.12"},{"v":0.549560622467874,"d":"0.55"},{"v":0.926680341036652,"d":"0.93"},"down","no"]
["ENSG00000173950","XXYLT1","ENST00000310380;ENST00000473200;ENST00000496644;ENST00000437101;ENST00000455281;ENST00000356740;ENST00000460582;ENST00000418940","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0046872(metal ion binding);GO:0016740(transferase activity);GO:0016757(transferase activity, transferring glycosyl groups);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0000287(magnesium ion binding);GO:0035252(UDP-xylosyltransferase activity);GO:0016266(O-glycan processing);GO:0030176(integral component of endoplasmic reticulum membrane);GO:0030145(manganese ion binding);GO:0030145(manganese ion binding)","NA","NA","NA","xyloside xylosyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:26639]",{"v":0.82799946422629,"d":"0.83"},{"v":0.513948430578665,"d":"0.51"},{"v":1.61105553585216,"d":"1.61"},{"v":0.688006227078333,"d":"0.69"},{"v":0.551987922594561,"d":"0.55"},{"v":0.928078144648999,"d":"0.93"},"up","no"]
["MSTRG.4467","MTHFD1","ENST00000216605;ENST00000545908;ENST00000555709;ENST00000556771;ENST00000555252;ENST00000554677;ENST00000556284;ENST00000557370;ENST00000555858;ENST00000553405;ENST00000554353","GO:0005524(ATP binding);GO:0005829(cytosol);GO:0055114(oxidation-reduction process);GO:0003824(catalytic activity);GO:0004488(methylenetetrahydrofolate dehydrogenase (NADP+) activity);GO:0004329(formate-tetrahydrofolate ligase activity);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0000166(nucleotide binding);GO:0016491(oxidoreductase activity);GO:0016787(hydrolase activity);GO:0006730(one-carbon metabolic process);GO:0016874(ligase activity);GO:0005515(protein binding);GO:0008152(metabolic process);GO:0008652(cellular amino acid biosynthetic process);GO:0006164(purine nucleotide biosynthetic process);GO:0035999(tetrahydrofolate interconversion);GO:0070062(extracellular exosome);GO:0005739(mitochondrion);GO:0001843(neural tube closure);GO:0007507(heart development);GO:0046655(folic acid metabolic process);GO:0004477(methenyltetrahydrofolate cyclohydrolase activity);GO:0004486(methylenetetrahydrofolate dehydrogenase [NAD(P)+] activity);GO:0004487(methylenetetrahydrofolate dehydrogenase (NAD+) activity);GO:0000105(histidine biosynthetic process);GO:0006555(methionine metabolic process);GO:0009069(serine family amino acid metabolic process);GO:0009070(serine family amino acid biosynthetic process);GO:0009086(methionine biosynthetic process);GO:0009113(purine nucleobase biosynthetic process);GO:0009257(10-formyltetrahydrofolate biosynthetic process);GO:0048702(embryonic neurocranium morphogenesis);GO:0048703(embryonic viscerocranium morphogenesis);GO:0061053(somite development);GO:0001780(neutrophil homeostasis);GO:0019346(transsulfuration);GO:0019346(transsulfuration)","00670(One carbon pool by folate);00670(One carbon pool by folate)","K00288","EC:1.5.1.5;EC:3.5.4.9","methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1 [Source:HGNC Symbol;Acc:HGNC:7432]",{"v":1.65926921552735,"d":"1.66"},{"v":1.80898572976432,"d":"1.81"},{"v":0.917237316042026,"d":"0.92"},{"v":-0.124633045492358,"d":"-0.12"},{"v":0.553629188533763,"d":"0.55"},{"v":0.928525126379291,"d":"0.93"},"down","no"]
["MSTRG.13240","NUS1","ENST00000368494","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016740(transferase activity);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005515(protein binding);GO:0007275(multicellular organism development);GO:0030154(cell differentiation);GO:0006486(protein glycosylation);GO:0016765(transferase activity, transferring alkyl or aryl (other than methyl) groups);GO:0003674(molecular_function);GO:0001525(angiogenesis);GO:0006489(dolichyl diphosphate biosynthetic process);GO:0004659(prenyltransferase activity);GO:0019408(dolichol biosynthetic process);GO:0032383(regulation of intracellular cholesterol transport);GO:0035268(protein mannosylation);GO:0042632(cholesterol homeostasis);GO:0055092(sterol homeostasis)","00900(Terpenoid backbone biosynthesis)","K19177","EC:2.5.1.87","NUS1 dehydrodolichyl diphosphate synthase subunit [Source:HGNC Symbol;Acc:HGNC:21042]",{"v":6.697866,"d":"6.70"},{"v":4.244144,"d":"4.24"},{"v":1.57814296593141,"d":"1.58"},{"v":0.658227906807313,"d":"0.66"},{"v":0.55425326455347,"d":"0.55"},{"v":0.928525126379291,"d":"0.93"},"up","no"]
["MSTRG.12411","RELL2","ENST00000518025;ENST00000444782;ENST00000297164","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0005518(collagen binding);GO:0010811(positive regulation of cell-substrate adhesion);GO:0005578(proteinaceous extracellular matrix);GO:0005604(basement membrane);GO:0005604(basement membrane)","NA","NA","NA","RELT like 2 [Source:HGNC Symbol;Acc:HGNC:26902]",{"v":1.60426229391371,"d":"1.60"},{"v":1.74970577542373,"d":"1.75"},{"v":0.916875463547694,"d":"0.92"},{"v":-0.125202304713151,"d":"-0.13"},{"v":0.555853837400904,"d":"0.56"},{"v":0.928525126379291,"d":"0.93"},"down","no"]
["MSTRG.11496","TNIP2","ENST00000315423;ENST00000505186;ENST00000502256;ENST00000503235;ENST00000507686;ENST00000510267;ENST00000511352","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0005829(cytosol);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0005515(protein binding);GO:0006915(apoptotic process);GO:0006954(inflammatory response);GO:0031593(polyubiquitin binding);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0019901(protein kinase binding);GO:0050821(protein stabilization);GO:0071222(cellular response to lipopolysaccharide);GO:0016579(protein deubiquitination);GO:0043123(positive regulation of I-kappaB kinase/NF-kappaB signaling);GO:2000352(negative regulation of endothelial cell apoptotic process);GO:0051403(stress-activated MAPK cascade);GO:0070498(interleukin-1-mediated signaling pathway);GO:0034138(toll-like receptor 3 signaling pathway);GO:0034134(toll-like receptor 2 signaling pathway);GO:0034162(toll-like receptor 9 signaling pathway);GO:0043032(positive regulation of macrophage activation);GO:0023035(CD40 signaling pathway);GO:0050871(positive regulation of B cell activation);GO:0007249(I-kappaB kinase/NF-kappaB signaling);GO:0007249(I-kappaB kinase/NF-kappaB signaling)","NA","NA","NA","TNFAIP3 interacting protein 2 [Source:HGNC Symbol;Acc:HGNC:19118]",{"v":7.39367583432614,"d":"7.39"},{"v":8.01982406180194,"d":"8.02"},{"v":0.921924942161996,"d":"0.92"},{"v":-0.117278795402535,"d":"-0.12"},{"v":0.556035107577591,"d":"0.56"},{"v":0.928525126379291,"d":"0.93"},"down","no"]
["ENSG00000271856","LINC01215","ENST00000607746","NA","NA","NA","NA","long intergenic non-protein coding RNA 1215 [Source:HGNC Symbol;Acc:HGNC:49651]",{"v":4.174454,"d":"4.17"},{"v":4.534847,"d":"4.53"},{"v":0.920528079558142,"d":"0.92"},{"v":-0.11946636503253,"d":"-0.12"},{"v":0.556750547474334,"d":"0.56"},{"v":0.928525126379291,"d":"0.93"},"down","no"]
["MSTRG.6693","LIG3","ENST00000378526;ENST00000593099;ENST00000585941;ENST00000586407;ENST00000586058;ENST00000586119;ENST00000590630;ENST00000586435;ENST00000262327;ENST00000588109","GO:0005634(nucleus);GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0005654(nucleoplasm);GO:0003677(DNA binding);GO:0051301(cell division);GO:0005739(mitochondrion);GO:0006281(DNA repair);GO:0016874(ligase activity);GO:0005515(protein binding);GO:0006310(DNA recombination);GO:0006974(cellular response to DNA damage stimulus);GO:0007049(cell cycle);GO:0006260(DNA replication);GO:0003909(DNA ligase activity);GO:0003910(DNA ligase (ATP) activity);GO:0051103(DNA ligation involved in DNA repair);GO:0071897(DNA biosynthetic process);GO:0006283(transcription-coupled nucleotide-excision repair);GO:0000724(double-strand break repair via homologous recombination);GO:0006288(base-excision repair, DNA ligation);GO:0006297(nucleotide-excision repair, DNA gap filling);GO:0006302(double-strand break repair);GO:0090298(negative regulation of mitochondrial DNA replication);GO:0006266(DNA ligation);GO:0006266(DNA ligation)","03410(Base excision repair);03410(Base excision repair)","K10776","EC:6.5.1.1","DNA ligase 3 [Source:HGNC Symbol;Acc:HGNC:6600]",{"v":1.11280624731016,"d":"1.11"},{"v":0.705485534174472,"d":"0.71"},{"v":1.57736224685644,"d":"1.58"},{"v":0.657514018231748,"d":"0.66"},{"v":0.55859427406461,"d":"0.56"},{"v":0.929355431645293,"d":"0.93"},"up","no"]
["MSTRG.11205","NCK1-AS1","ENST00000461864;ENST00000474250;ENST00000470236","NA","NA","NA","NA","NCK1 antisense RNA 1 (head to head) [Source:HGNC Symbol;Acc:HGNC:49645]",{"v":1.54692862211337,"d":"1.55"},{"v":1.6843641546536,"d":"1.68"},{"v":0.918405095382421,"d":"0.92"},{"v":-0.122797448668015,"d":"-0.12"},{"v":0.560993091848707,"d":"0.56"},{"v":0.930953526098748,"d":"0.93"},"down","no"]
["MSTRG.13270","TRMT11","ENST00000334379;ENST00000461129;ENST00000479748;ENST00000446681;ENST00000473273;ENST00000468097;ENST00000444121","GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0008168(methyltransferase activity);GO:0016740(transferase activity);GO:0008033(tRNA processing);GO:0032259(methylation);GO:0000049(tRNA binding);GO:0030488(tRNA methylation);GO:0004809(tRNA (guanine-N2-)-methyltransferase activity);GO:0004809(tRNA (guanine-N2-)-methyltransferase activity)","NA","NA","NA","tRNA methyltransferase 11 homolog [Source:HGNC Symbol;Acc:HGNC:21080]",{"v":1.13033301710037,"d":"1.13"},{"v":1.23769428289963,"d":"1.24"},{"v":0.913257039898627,"d":"0.91"},{"v":-0.130907125152856,"d":"-0.13"},{"v":0.561529706871992,"d":"0.56"},{"v":0.930959583197062,"d":"0.93"},"down","no"]
["MSTRG.13545","MTURN","MSTRG.13545.4;MSTRG.13545.2;ENST00000409688;ENST00000324453;ENST00000324489","GO:0007275(multicellular organism development);GO:0007275(multicellular organism development)","NA","NA","NA","maturin, neural progenitor differentiation regulator homolog [Source:HGNC Symbol;Acc:HGNC:25457]",{"v":12.8902286625344,"d":"12.89"},{"v":8.22681581726354,"d":"8.23"},{"v":1.56685514163146,"d":"1.57"},{"v":0.647871806415344,"d":"0.65"},{"v":0.564191613624549,"d":"0.56"},{"v":0.93240237406598,"d":"0.93"},"up","no"]
["MSTRG.13287","AL032821.1","ENST00000430895","NA","NA","NA","NA",null,{"v":2.097347,"d":"2.10"},{"v":1.304401,"d":"1.30"},{"v":1.60790048459024,"d":"1.61"},{"v":0.685178118686649,"d":"0.69"},{"v":0.564590412328363,"d":"0.56"},{"v":0.93240237406598,"d":"0.93"},"up","no"]
["ENSG00000156697","UTP14A","ENST00000394422;ENST00000425117;ENST00000498179;ENST00000427972","GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005730(nucleolus);GO:0005829(cytosol);GO:0005515(protein binding);GO:0042254(ribosome biogenesis);GO:0006364(rRNA processing);GO:0032040(small-subunit processome);GO:0005654(nucleoplasm);GO:0030490(maturation of SSU-rRNA);GO:0030490(maturation of SSU-rRNA)","03008(Ribosome biogenesis in eukaryotes);03008(Ribosome biogenesis in eukaryotes)","K14567","NA","UTP14A, small subunit processome component [Source:HGNC Symbol;Acc:HGNC:10665]",{"v":2.60230433276242,"d":"2.60"},{"v":2.80206933594323,"d":"2.80"},{"v":0.928708044223479,"d":"0.93"},{"v":-0.106702963672689,"d":"-0.11"},{"v":0.565827552383836,"d":"0.57"},{"v":0.93240237406598,"d":"0.93"},"down","no"]
["MSTRG.10447","PLA2G6","ENST00000332509;ENST00000448094;ENST00000452794;ENST00000480154;ENST00000498338;ENST00000491986;ENST00000463287;ENST00000496409;ENST00000447598;ENST00000452542;ENST00000454670;ENST00000452972;ENST00000420435;ENST00000427453;ENST00000471636;ENST00000445591;ENST00000427114;ENST00000402064;ENST00000490473","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005829(cytosol);GO:0016787(hydrolase activity);GO:0006629(lipid metabolic process);GO:0008152(metabolic process);GO:0016042(lipid catabolic process);GO:0005815(microtubule organizing center);GO:0005615(extracellular space);GO:0004623(phospholipase A2 activity);GO:0006935(chemotaxis);GO:0038096(Fc-gamma receptor signaling pathway involved in phagocytosis);GO:0005516(calmodulin binding);GO:0019731(antibacterial humoral response);GO:0036151(phosphatidylcholine acyl-chain remodeling);GO:0036152(phosphatidylethanolamine acyl-chain remodeling);GO:0019901(protein kinase binding);GO:0043008(ATP-dependent protein binding);GO:0047499(calcium-independent phospholipase A2 activity);GO:0001934(positive regulation of protein phosphorylation);GO:0007204(positive regulation of cytosolic calcium ion concentration);GO:0007613(memory);GO:0014832(urinary bladder smooth muscle contraction);GO:0032049(cardiolipin biosynthetic process);GO:0034976(response to endoplasmic reticulum stress);GO:0035774(positive regulation of insulin secretion involved in cellular response to glucose stimulus);GO:0045921(positive regulation of exocytosis);GO:0051967(negative regulation of synaptic transmission, glutamatergic);GO:0060135(maternal process involved in female pregnancy);GO:0090037(positive regulation of protein kinase C signaling);GO:0090200(positive regulation of release of cytochrome c from mitochondria);GO:0090238(positive regulation of arachidonic acid secretion);GO:0097755(positive regulation of blood vessel diameter);GO:1901339(regulation of store-operated calcium channel activity);GO:2000304(positive regulation of ceramide biosynthetic process);GO:0005739(mitochondrion);GO:0016021(integral component of membrane);GO:0016021(integral component of membrane)","00564(Glycerophospholipid metabolism);00565(Ether lipid metabolism);00590(Arachidonic acid metabolism);00591(Linoleic acid metabolism);00592(alpha-Linolenic acid metabolism);04014(Ras signaling pathway);04666(Fc gamma R-mediated phagocytosis);04270(Vascular smooth muscle contraction);04750(Inflammatory mediator regulation of TRP channels);04750(Inflammatory mediator regulation of TRP channels)","K16343","EC:3.1.1.4","phospholipase A2 group VI [Source:HGNC Symbol;Acc:HGNC:9039]",{"v":1.43841333782184,"d":"1.44"},{"v":0.912177698579461,"d":"0.91"},{"v":1.57690035621556,"d":"1.58"},{"v":0.657091499611298,"d":"0.66"},{"v":0.5676686320704,"d":"0.57"},{"v":0.933003828073822,"d":"0.93"},"up","no"]
["ENSG00000137501","SYTL2","ENST00000525702;ENST00000316356;ENST00000389960;ENST00000524911;ENST00000533057;ENST00000529662;ENST00000524830;ENST00000531496;ENST00000354566;ENST00000532221;ENST00000438197;ENST00000634661;ENST00000527523;ENST00000533577;ENST00000528231;ENST00000525692;ENST00000528566;ENST00000529534;ENST00000359152;ENST00000529581","GO:0006887(exocytosis);GO:0017137(Rab GTPase binding);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0006886(intracellular protein transport);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0042470(melanosome);GO:0016192(vesicle-mediated transport);GO:0005509(calcium ion binding);GO:0005544(calcium-dependent phospholipid binding);GO:0019905(syntaxin binding);GO:0030276(clathrin binding);GO:0006906(vesicle fusion);GO:0006904(vesicle docking involved in exocytosis);GO:0019902(phosphatase binding);GO:0010923(negative regulation of phosphatase activity);GO:0005546(phosphatidylinositol-4,5-bisphosphate binding);GO:0001786(phosphatidylserine binding);GO:0070382(exocytic vesicle);GO:0019897(extrinsic component of plasma membrane);GO:0042043(neurexin family protein binding);GO:0070257(positive regulation of mucus secretion);GO:0072659(protein localization to plasma membrane);GO:0005622(intracellular);GO:0005622(intracellular)","NA","NA","NA","synaptotagmin like 2 [Source:HGNC Symbol;Acc:HGNC:15585]",{"v":2.26092358269675,"d":"2.26"},{"v":1.4451708653402,"d":"1.45"},{"v":1.56446800646269,"d":"1.56"},{"v":0.645672155613309,"d":"0.65"},{"v":0.568500601006263,"d":"0.57"},{"v":0.933295249737213,"d":"0.93"},"up","no"]
["MSTRG.7524","MBD1","ENST00000398493;ENST00000347968;ENST00000269468;ENST00000590208;ENST00000589541;ENST00000591416;ENST00000591535;ENST00000585595;ENST00000586884;ENST00000398495;ENST00000382948;ENST00000586118;ENST00000589733;ENST00000269471;ENST00000590215;MSTRG.7524.22;ENST00000585672;ENST00000587605;ENST00000589867;ENST00000591661;ENST00000589758;ENST00000586679;ENST00000398488","GO:0005634(nucleus);GO:0016607(nuclear speck);GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0005694(chromosome);GO:0005515(protein binding);GO:0045892(negative regulation of transcription, DNA-templated);GO:0016363(nuclear matrix);GO:0006366(transcription from RNA polymerase II promoter);GO:0008327(methyl-CpG binding);GO:0010385(double-stranded methylated DNA binding);GO:0003682(chromatin binding);GO:0007507(heart development);GO:0007568(aging);GO:0010629(negative regulation of gene expression);GO:0014070(response to organic cyclic compound);GO:0030182(neuron differentiation);GO:0031667(response to nutrient levels);GO:0032355(response to estradiol);GO:0042220(response to cocaine);GO:0042493(response to drug);GO:0044030(regulation of DNA methylation);GO:0048712(negative regulation of astrocyte differentiation);GO:0000790(nuclear chromatin);GO:0005737(cytoplasm);GO:0005737(cytoplasm)","NA","NA","NA","methyl-CpG binding domain protein 1 [Source:HGNC Symbol;Acc:HGNC:6916]",{"v":4.83284188342738,"d":"4.83"},{"v":3.09441291461241,"d":"3.09"},{"v":1.56179605527297,"d":"1.56"},{"v":0.643206073674348,"d":"0.64"},{"v":0.569910431522785,"d":"0.57"},{"v":0.93356213114894,"d":"0.93"},"up","no"]
["MSTRG.10235","AP000347.1;GUSBP11;AP000347.2;ASLP1;AP000346.2;DRICH1;AP000346.1","ENST00000417194;ENST00000445682;ENST00000423913;ENST00000452737;ENST00000428790;ENST00000425948;ENST00000437862;ENST00000458554;ENST00000437294;ENST00000422506;ENST00000455485;ENST00000438858;ENST00000430707;ENST00000421064;ENST00000430357;ENST00000317749;ENST00000390329;ENST00000435868;ENST00000451837","GO:0005515(protein binding)","NA","NA","NA","glucuronidase, beta pseudogene 11 [Source:HGNC Symbol;Acc:HGNC:42325];argininosuccinate lyase pseudogene 1 [Source:HGNC Symbol;Acc:HGNC:747];aspartate rich 1 [Source:HGNC Symbol;Acc:HGNC:28031]",{"v":1.54681674150445,"d":"1.55"},{"v":0.987447920983174,"d":"0.99"},{"v":1.56647931362732,"d":"1.57"},{"v":0.647525718113481,"d":"0.65"},{"v":0.571127336035791,"d":"0.57"},{"v":0.934670718109042,"d":"0.93"},"up","no"]
["ENSG00000163002","NUP35","ENST00000295119;ENST00000374930;ENST00000455063;ENST00000479162","GO:0003676(nucleic acid binding);GO:0006810(transport);GO:0051028(mRNA transport);GO:0005634(nucleus);GO:0016020(membrane);GO:0015031(protein transport);GO:0005654(nucleoplasm);GO:0031965(nuclear membrane);GO:0005886(plasma membrane);GO:0006913(nucleocytoplasmic transport);GO:0005515(protein binding);GO:0005643(nuclear pore);GO:0006355(regulation of transcription, DNA-templated);GO:0075733(intracellular transport of virus);GO:0043657(host cell);GO:0006607(NLS-bearing protein import into nucleus);GO:0003697(single-stranded DNA binding);GO:0016032(viral process);GO:0006406(mRNA export from nucleus);GO:0016925(protein sumoylation);GO:0060964(regulation of gene silencing by miRNA);GO:0006110(regulation of glycolytic process);GO:0006409(tRNA export from nucleus);GO:0007077(mitotic nuclear envelope disassembly);GO:0019083(viral transcription);GO:1900034(regulation of cellular response to heat);GO:0005635(nuclear envelope);GO:0044613(nuclear pore central transport channel);GO:0044615(nuclear pore nuclear basket);GO:0005487(nucleocytoplasmic transporter activity);GO:0005543(phospholipid binding);GO:0006999(nuclear pore organization);GO:0005652(nuclear lamina);GO:0005652(nuclear lamina)","03013(RNA transport);03013(RNA transport)","K14313","NA","nucleoporin 35 [Source:HGNC Symbol;Acc:HGNC:29797]",{"v":0.755349456005932,"d":"0.76"},{"v":0.8189644935739,"d":"0.82"},{"v":0.92232259387662,"d":"0.92"},{"v":-0.116656655310852,"d":"-0.12"},{"v":0.57336960102333,"d":"0.57"},{"v":0.935520510553306,"d":"0.94"},"down","no"]
["MSTRG.11051","LINC00877","ENST00000468646;ENST00000488545;ENST00000470712;ENST00000498432;ENST00000608654;ENST00000462492;ENST00000464271","NA","NA","NA","NA","long intergenic non-protein coding RNA 877 [Source:HGNC Symbol;Acc:HGNC:27706]",{"v":1.39271795182452,"d":"1.39"},{"v":0.885842053710537,"d":"0.89"},{"v":1.57219669803531,"d":"1.57"},{"v":0.652781724929687,"d":"0.65"},{"v":0.574948326145859,"d":"0.57"},{"v":0.935550608880597,"d":"0.94"},"up","no"]
["MSTRG.2579","RAB1B","ENST00000311481;ENST00000527397","GO:0006810(transport);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0015031(protein transport);GO:0005525(GTP binding);GO:0000166(nucleotide binding);GO:0003924(GTPase activity);GO:0005515(protein binding);GO:0006914(autophagy);GO:0034045(pre-autophagosomal structure membrane);GO:0005789(endoplasmic reticulum membrane);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0006890(retrograde vesicle-mediated transport, Golgi to ER);GO:0043687(post-translational protein modification);GO:0006888(ER to Golgi vesicle-mediated transport);GO:0000139(Golgi membrane);GO:0030133(transport vesicle);GO:0048208(COPII vesicle coating);GO:0005794(Golgi apparatus);GO:0033116(endoplasmic reticulum-Golgi intermediate compartment membrane);GO:0019068(virion assembly);GO:1903020(positive regulation of glycoprotein metabolic process);GO:2000785(regulation of autophagosome assembly);GO:0005739(mitochondrion);GO:0005793(endoplasmic reticulum-Golgi intermediate compartment);GO:0005793(endoplasmic reticulum-Golgi intermediate compartment)","05134(Legionellosis);05134(Legionellosis)","K07875","NA","RAB1B, member RAS oncogene family [Source:HGNC Symbol;Acc:HGNC:18370]",{"v":78.907661,"d":"78.91"},{"v":84.418434,"d":"84.42"},{"v":0.934720738837681,"d":"0.93"},{"v":-0.0973926912479135,"d":"-0.10"},{"v":0.575305880940853,"d":"0.58"},{"v":0.935550608880597,"d":"0.94"},"down","no"]
["MSTRG.4639","SERPINA1","MSTRG.4639.5;ENST00000557093;ENST00000404814;ENST00000555289;ENST00000449399;ENST00000440909;ENST00000355814;ENST00000557492;ENST00000393087;ENST00000489769;ENST00000448921;ENST00000393088;ENST00000636712;ENST00000437397;ENST00000557361;ENST00000556955;ENST00000557118;ENST00000554720;ENST00000553327;ENST00000402629;ENST00000556091","GO:0005615(extracellular space);GO:0043231(intracellular membrane-bounded organelle);GO:0005794(Golgi apparatus);GO:0010951(negative regulation of endopeptidase activity);GO:0005783(endoplasmic reticulum);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0005578(proteinaceous extracellular matrix);GO:0030414(peptidase inhibitor activity);GO:0010466(negative regulation of peptidase activity);GO:0042802(identical protein binding);GO:0000139(Golgi membrane);GO:0070062(extracellular exosome);GO:0044267(cellular protein metabolic process);GO:0043687(post-translational protein modification);GO:0004867(serine-type endopeptidase inhibitor activity);GO:0043312(neutrophil degranulation);GO:0006953(acute-phase response);GO:0002576(platelet degranulation);GO:0002020(protease binding);GO:1904813(ficolin-1-rich granule lumen);GO:0007596(blood coagulation);GO:0007599(hemostasis);GO:0005788(endoplasmic reticulum lumen);GO:0031093(platelet alpha granule lumen);GO:0006888(ER to Golgi vesicle-mediated transport);GO:0048208(COPII vesicle coating);GO:0033116(endoplasmic reticulum-Golgi intermediate compartment membrane);GO:0030134(ER to Golgi transport vesicle);GO:0030134(ER to Golgi transport vesicle)","04610(Complement and coagulation cascades);04610(Complement and coagulation cascades)","K03984","NA","serpin family A member 1 [Source:HGNC Symbol;Acc:HGNC:8941]",{"v":106.62435299592,"d":"106.62"},{"v":114.000320512648,"d":"114.00"},{"v":0.935298712463623,"d":"0.94"},{"v":-0.0965008933472211,"d":"-0.10"},{"v":0.576096894265549,"d":"0.58"},{"v":0.93595596434049,"d":"0.94"},"down","no"]
["MSTRG.90","TNFRSF14-AS1","ENST00000416860;ENST00000452793;ENST00000432521;ENST00000443892;ENST00000449660","NA","NA","NA","NA","TNFRSF14 antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:26966]",{"v":0.377691870457878,"d":"0.38"},{"v":0.242922159361251,"d":"0.24"},{"v":1.55478558008457,"d":"1.55"},{"v":0.636715632524146,"d":"0.64"},{"v":0.577937215422354,"d":"0.58"},{"v":0.936839114417765,"d":"0.94"},"up","no"]
["ENSG00000095002","MSH2","ENST00000233146;ENST00000467323;ENST00000406134;ENST00000461394","GO:0005634(nucleus);GO:0016020(membrane);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0006281(DNA repair);GO:0006974(cellular response to DNA damage stimulus);GO:0030983(mismatched DNA binding);GO:0006298(mismatch repair);GO:0032301(MutSalpha complex);GO:0005654(nucleoplasm);GO:0019901(protein kinase binding);GO:0006302(double-strand break repair);GO:0031573(intra-S DNA damage checkpoint);GO:0000784(nuclear chromosome, telomeric region);GO:0008022(protein C-terminus binding);GO:0032300(mismatch repair complex);GO:0019899(enzyme binding);GO:0010165(response to X-ray);GO:0008094(DNA-dependent ATPase activity);GO:0043524(negative regulation of neuron apoptotic process);GO:0030183(B cell differentiation);GO:0042803(protein homodimerization activity);GO:0003697(single-stranded DNA binding);GO:0032405(MutLalpha complex binding);GO:0016887(ATPase activity);GO:0008584(male gonad development);GO:0032139(dinucleotide insertion or deletion binding);GO:0032142(single guanine insertion binding);GO:0032181(dinucleotide repeat insertion binding);GO:0000403(Y-form DNA binding);GO:0000404(heteroduplex DNA loop binding);GO:0000406(double-strand/single-strand DNA junction binding);GO:0043570(maintenance of DNA repeat elements);GO:0045910(negative regulation of DNA recombination);GO:0051096(positive regulation of helicase activity);GO:0032302(MutSbeta complex);GO:0000287(magnesium ion binding);GO:0016446(somatic hypermutation of immunoglobulin genes);GO:0000400(four-way junction DNA binding);GO:0003690(double-stranded DNA binding);GO:0032137(guanine/thymine mispair binding);GO:0032143(single thymine insertion binding);GO:0032357(oxidized purine DNA binding);GO:0043531(ADP binding);GO:0003684(damaged DNA binding);GO:0019237(centromeric DNA binding);GO:0001701(in utero embryonic development);GO:0002204(somatic recombination of immunoglobulin genes involved in immune response);GO:0006119(oxidative phosphorylation);GO:0006301(postreplication repair);GO:0006311(meiotic gene conversion);GO:0007050(cell cycle arrest);GO:0007281(germ cell development);GO:0008340(determination of adult lifespan);GO:0008630(intrinsic apoptotic signaling pathway in response to DNA damage);GO:0010224(response to UV-B);GO:0016447(somatic recombination of immunoglobulin gene segments);GO:0019724(B cell mediated immunity);GO:0042771(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator);GO:0045128(negative regulation of reciprocal meiotic recombination);GO:0045190(isotype switching);GO:0048298(positive regulation of isotype switching to IgA isotypes);GO:0048304(positive regulation of isotype switching to IgG isotypes);GO:0048304(positive regulation of isotype switching to IgG isotypes)","03430(Mismatch repair);05200(Pathways in cancer);05210(Colorectal cancer);01524(Platinum drug resistance);01524(Platinum drug resistance)","K08735","NA","mutS homolog 2 [Source:HGNC Symbol;Acc:HGNC:7325]",{"v":3.89041704261863,"d":"3.89"},{"v":2.50728501559754,"d":"2.51"},{"v":1.55164531292485,"d":"1.55"},{"v":0.633798812831287,"d":"0.63"},{"v":0.580413369957504,"d":"0.58"},{"v":0.93824338325675,"d":"0.94"},"up","no"]
["ENSG00000240857","RDH14","ENST00000381249;ENST00000468071","GO:0005634(nucleus);GO:0016020(membrane);GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0005765(lysosomal membrane);GO:0005789(endoplasmic reticulum membrane);GO:0005783(endoplasmic reticulum);GO:0001649(osteoblast differentiation);GO:0052650(NADP-retinol dehydrogenase activity);GO:0008106(alcohol dehydrogenase (NADP+) activity);GO:0042572(retinol metabolic process);GO:0005739(mitochondrion);GO:0005739(mitochondrion)","NA","NA","NA","retinol dehydrogenase 14 (all-trans/9-cis/11-cis) [Source:HGNC Symbol;Acc:HGNC:19979]",{"v":3.184756,"d":"3.18"},{"v":2.03959,"d":"2.04"},{"v":1.56146872655779,"d":"1.56"},{"v":0.642903675031362,"d":"0.64"},{"v":0.581141014834159,"d":"0.58"},{"v":0.93892662306891,"d":"0.94"},"up","no"]
["MSTRG.13185","RTN4IP1","ENST00000369063;ENST00000498091","GO:0016020(membrane);GO:0008270(zinc ion binding);GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0005739(mitochondrion);GO:0005741(mitochondrial outer membrane);GO:0007399(nervous system development);GO:0050773(regulation of dendrite development);GO:0050773(regulation of dendrite development)","NA","NA","NA","reticulon 4 interacting protein 1 [Source:HGNC Symbol;Acc:HGNC:18647]",{"v":0.724256930091185,"d":"0.72"},{"v":0.785980535967579,"d":"0.79"},{"v":0.921469294655739,"d":"0.92"},{"v":-0.117992001940701,"d":"-0.12"},{"v":0.583817170604605,"d":"0.58"},{"v":0.940472853687235,"d":"0.94"},"down","no"]
["MSTRG.8616","LBH","ENST00000467242;ENST00000395323;ENST00000484150;ENST00000401506;ENST00000407930;ENST00000406087;ENST00000404397;ENST00000412933;ENST00000464412","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0007275(multicellular organism development);GO:0010468(regulation of gene expression);GO:0030193(regulation of blood coagulation);GO:0030879(mammary gland development);GO:0033147(negative regulation of intracellular estrogen receptor signaling pathway);GO:0045893(positive regulation of transcription, DNA-templated);GO:0060644(mammary gland epithelial cell differentiation);GO:1904674(positive regulation of somatic stem cell population maintenance);GO:1904677(positive regulation of somatic stem cell division);GO:2000103(positive regulation of mammary stem cell proliferation);GO:2000737(negative regulation of stem cell differentiation);GO:2000737(negative regulation of stem cell differentiation)","NA","NA","NA","limb bud and heart development [Source:HGNC Symbol;Acc:HGNC:29532]",{"v":27.6416185667034,"d":"27.64"},{"v":29.3769500432194,"d":"29.38"},{"v":0.940928807314477,"d":"0.94"},{"v":-0.0878425251958857,"d":"-0.09"},{"v":0.58540716299883,"d":"0.59"},{"v":0.940958805930382,"d":"0.94"},"down","no"]
["MSTRG.13372","TFB1M","ENST00000367166;ENST00000475849;ENST00000468889;ENST00000480390;ENST00000489874;ENST00000466349;ENST00000495806","GO:0003723(RNA binding);GO:0008168(methyltransferase activity);GO:0016740(transferase activity);GO:0032259(methylation);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0005739(mitochondrion);GO:0005515(protein binding);GO:0006364(rRNA processing);GO:0000179(rRNA (adenine-N6,N6-)-dimethyltransferase activity);GO:0008649(rRNA methyltransferase activity);GO:0000154(rRNA modification);GO:0031167(rRNA methylation);GO:0005759(mitochondrial matrix);GO:0007005(mitochondrion organization);GO:0042645(mitochondrial nucleoid);GO:0042645(mitochondrial nucleoid)","NA","NA","NA","transcription factor B1, mitochondrial [Source:HGNC Symbol;Acc:HGNC:17037]",{"v":1.22859821016082,"d":"1.23"},{"v":1.32737157419591,"d":"1.33"},{"v":0.92558725382158,"d":"0.93"},{"v":-0.111559097528187,"d":"-0.11"},{"v":0.586162377333969,"d":"0.59"},{"v":0.94137791287227,"d":"0.94"},"down","no"]
["ENSG00000121940","CLCC1","ENST00000356970;ENST00000369968;ENST00000369976;ENST00000302500","GO:0006810(transport);GO:0005634(nucleus);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0043231(intracellular membrane-bounded organelle);GO:0005783(endoplasmic reticulum);GO:0005794(Golgi apparatus);GO:0006811(ion transport);GO:0005254(chloride channel activity);GO:0006821(chloride transport);GO:0034707(chloride channel complex);GO:1902476(chloride transmembrane transport);GO:1902476(chloride transmembrane transport)","NA","NA","NA","chloride channel CLIC like 1 [Source:HGNC Symbol;Acc:HGNC:29675]",{"v":1.36368402860596,"d":"1.36"},{"v":0.879293100322321,"d":"0.88"},{"v":1.55088676131551,"d":"1.55"},{"v":0.633093351201452,"d":"0.63"},{"v":0.588295953772302,"d":"0.59"},{"v":0.941855577352481,"d":"0.94"},"up","no"]
["ENSG00000170260","ZNF212","ENST00000335870;ENST00000462724;ENST00000488917","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0005622(intracellular);GO:0008270(zinc ion binding);GO:0005515(protein binding);GO:0042802(identical protein binding);GO:0042802(identical protein binding)","NA","NA","NA","zinc finger protein 212 [Source:HGNC Symbol;Acc:HGNC:13004]",{"v":3.00993132023884,"d":"3.01"},{"v":1.94683105279698,"d":"1.95"},{"v":1.54606703849033,"d":"1.55"},{"v":0.628602876831118,"d":"0.63"},{"v":0.589177653633668,"d":"0.59"},{"v":0.941855577352481,"d":"0.94"},"up","no"]
["ENSG00000106993","CDC37L1","ENST00000381854;ENST00000479095;ENST00000381858","GO:0005829(cytosol);GO:0005737(cytoplasm);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0002576(platelet degranulation);GO:0006457(protein folding);GO:0051087(chaperone binding);GO:0031089(platelet dense granule lumen);GO:0051082(unfolded protein binding);GO:0050821(protein stabilization);GO:0031072(heat shock protein binding);GO:0031072(heat shock protein binding)","NA","NA","NA","cell division cycle 37 like 1 [Source:HGNC Symbol;Acc:HGNC:17179]",{"v":2.63994224968346,"d":"2.64"},{"v":2.803169620157,"d":"2.80"},{"v":0.941770426841171,"d":"0.94"},{"v":-0.0865526745640609,"d":"-0.09"},{"v":0.59030901033805,"d":"0.59"},{"v":0.941855577352481,"d":"0.94"},"down","no"]
["MSTRG.304","STX12","ENST00000373943;ENST00000481874;ENST00000468761;ENST00000472285;ENST00000440806","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0006886(intracellular protein transport);GO:0015031(protein transport);GO:0016192(vesicle-mediated transport);GO:0005794(Golgi apparatus);GO:0005515(protein binding);GO:0000139(Golgi membrane);GO:0012505(endomembrane system);GO:0006906(vesicle fusion);GO:0005484(SNAP receptor activity);GO:0005768(endosome);GO:0070062(extracellular exosome);GO:0010008(endosome membrane);GO:0000149(SNARE binding);GO:0048278(vesicle docking);GO:0031201(SNARE complex);GO:0050821(protein stabilization);GO:0031982(vesicle);GO:0033344(cholesterol efflux);GO:0045121(membrane raft);GO:0031083(BLOC-1 complex);GO:0045335(phagocytic vesicle);GO:0000045(autophagosome assembly);GO:0000407(pre-autophagosomal structure);GO:0000407(pre-autophagosomal structure)","04145(Phagosome);04145(Phagosome)","K13813","NA","syntaxin 12 [Source:HGNC Symbol;Acc:HGNC:11430]",{"v":6.24638823816953,"d":"6.25"},{"v":6.61794570800832,"d":"6.62"},{"v":0.943856071622169,"d":"0.94"},{"v":-0.0833612147366688,"d":"-0.08"},{"v":0.591509703943883,"d":"0.59"},{"v":0.941855577352481,"d":"0.94"},"down","no"]
["MSTRG.6105","ATXN1L;IST1","ENST00000427980;ENST00000329908;ENST00000378798;ENST00000535424;ENST00000378799;ENST00000538565;ENST00000534994;ENST00000538104;ENST00000538850;ENST00000536027;ENST00000538709;ENST00000456820;ENST00000544564;ENST00000537571;ENST00000606369;ENST00000545388;ENST00000541918;ENST00000566536;ENST00000568581;ENST00000541180;ENST00000569119;ENST00000537613;ENST00000545518;ENST00000541571;ENST00000539186;ENST00000565676","GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005730(nucleolus);GO:0005654(nucleoplasm);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0042995(cell projection);GO:0005515(protein binding);GO:0030425(dendrite);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0030198(extracellular matrix organization);GO:0048286(lung alveolus development);GO:1902035(positive regulation of hematopoietic stem cell proliferation);GO:0015031(protein transport);GO:0043231(intracellular membrane-bounded organelle);GO:0005737(cytoplasm);GO:0051301(cell division);GO:0005829(cytosol);GO:0005856(cytoskeleton);GO:0007049(cell cycle);GO:0031410(cytoplasmic vesicle);GO:0005813(centrosome);GO:0005815(microtubule organizing center);GO:0030496(midbody);GO:0005576(extracellular region);GO:0045296(cadherin binding);GO:0070062(extracellular exosome);GO:0036258(multivesicular body assembly);GO:0043312(neutrophil degranulation);GO:0019904(protein domain specific binding);GO:0032403(protein complex binding);GO:0035578(azurophil granule lumen);GO:0005635(nuclear envelope);GO:0000910(cytokinesis);GO:0005793(endoplasmic reticulum-Golgi intermediate compartment);GO:0045862(positive regulation of proteolysis);GO:0000785(chromatin);GO:0045184(establishment of protein localization);GO:1904903(ESCRT III complex disassembly);GO:0008104(protein localization);GO:0019076(viral release from host cell);GO:0090543(Flemming body);GO:0090541(MIT domain binding);GO:0009838(abscission);GO:0046745(viral capsid secondary envelopment);GO:0048672(positive regulation of collateral sprouting);GO:1902035(positive regulation of hematopoietic stem cell proliferation)","04144(Endocytosis);04144(Endocytosis)","K19476","NA","ataxin 1 like [Source:HGNC Symbol;Acc:HGNC:33279];IST1, ESCRT-III associated factor [Source:HGNC Symbol;Acc:HGNC:28977]",{"v":9.87362212652429,"d":"9.87"},{"v":6.4225910180749,"d":"6.42"},{"v":1.53732692907539,"d":"1.54"},{"v":0.620424002244408,"d":"0.62"},{"v":0.59164097278435,"d":"0.59"},{"v":0.941855577352481,"d":"0.94"},"up","no"]
["MSTRG.10704","HACL1","ENST00000321169;ENST00000460907;ENST00000457447;ENST00000422591;ENST00000456194;ENST00000383779;ENST00000472857;ENST00000421993;ENST00000451445","GO:0043231(intracellular membrane-bounded organelle);GO:0046872(metal ion binding);GO:0000287(magnesium ion binding);GO:0003824(catalytic activity);GO:0016829(lyase activity);GO:0006631(fatty acid metabolic process);GO:0005515(protein binding);GO:0048037(cofactor binding);GO:0005777(peroxisome);GO:0042802(identical protein binding);GO:0030976(thiamine pyrophosphate binding);GO:0005102(receptor binding);GO:0005782(peroxisomal matrix);GO:0051259(protein oligomerization);GO:0001561(fatty acid alpha-oxidation);GO:0016830(carbon-carbon lyase activity);GO:0006629(lipid metabolic process);GO:0006629(lipid metabolic process)","04146(Peroxisome);04146(Peroxisome)","K12261","EC:4.1.-.-","2-hydroxyacyl-CoA lyase 1 [Source:HGNC Symbol;Acc:HGNC:17856]",{"v":2.55850607855974,"d":"2.56"},{"v":2.71591731947627,"d":"2.72"},{"v":0.942041224971133,"d":"0.94"},{"v":-0.0861378994229334,"d":"-0.09"},{"v":0.594476373634666,"d":"0.59"},{"v":0.942921085244922,"d":"0.94"},"down","no"]
["ENSG00000122121","XPNPEP2","ENST00000371106","GO:0016787(hydrolase activity);GO:0016020(membrane);GO:0046872(metal ion binding);GO:0005886(plasma membrane);GO:0008233(peptidase activity);GO:0006508(proteolysis);GO:0008237(metallopeptidase activity);GO:0031225(anchored component of membrane);GO:0004177(aminopeptidase activity);GO:0005576(extracellular region);GO:0070006(metalloaminopeptidase activity);GO:0070062(extracellular exosome);GO:0006501(C-terminal protein lipidation)","04974(Protein digestion and absorption)","K14208","EC:3.4.11.9","X-prolyl aminopeptidase 2 [Source:HGNC Symbol;Acc:HGNC:12823]",{"v":0.360054094285714,"d":"0.36"},{"v":0.225530031428571,"d":"0.23"},{"v":1.59647959965699,"d":"1.60"},{"v":0.67489411779261,"d":"0.67"},{"v":0.594873979829604,"d":"0.59"},{"v":0.942921085244922,"d":"0.94"},"up","no"]
["MSTRG.1530","RBM17","ENST00000379888;ENST00000496762;ENST00000432931;ENST00000437845;ENST00000447032;ENST00000446108;ENST00000476706;ENST00000481147;ENST00000467214;ENST00000465906;ENST00000467080;ENST00000418631","GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0006397(mRNA processing);GO:0008380(RNA splicing);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0006281(DNA repair);GO:0005515(protein binding);GO:0005681(spliceosomal complex);GO:0043484(regulation of RNA splicing);GO:0000398(mRNA splicing, via spliceosome);GO:0000380(alternative mRNA splicing, via spliceosome);GO:0043234(protein complex);GO:0043234(protein complex)","03040(Spliceosome);03040(Spliceosome)","K12840","NA","RNA binding motif protein 17 [Source:HGNC Symbol;Acc:HGNC:16944]",{"v":4.23775411029755,"d":"4.24"},{"v":2.75820586960586,"d":"2.76"},{"v":1.53641689947644,"d":"1.54"},{"v":0.619569737672559,"d":"0.62"},{"v":0.596266317486047,"d":"0.60"},{"v":0.942921085244922,"d":"0.94"},"up","no"]
["MSTRG.7837","SWSAP1","ENST00000312423","GO:0005634(nucleus);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0006281(DNA repair);GO:0006310(DNA recombination);GO:0006974(cellular response to DNA damage stimulus);GO:0016887(ATPase activity);GO:0003697(single-stranded DNA binding);GO:0050821(protein stabilization);GO:0000724(double-strand break repair via homologous recombination);GO:0097196(Shu complex);GO:0000725(recombinational repair)","NA","NA","NA","SWIM-type zinc finger 7 associated protein 1 [Source:HGNC Symbol;Acc:HGNC:26638]",{"v":0.721957,"d":"0.72"},{"v":0.781529,"d":"0.78"},{"v":0.923775061450055,"d":"0.92"},{"v":-0.114386495667262,"d":"-0.11"},{"v":0.597321066688428,"d":"0.60"},{"v":0.943082615557431,"d":"0.94"},"down","no"]
["ENSG00000164109","MAD2L1","ENST00000296509;ENST00000511295;ENST00000504707;ENST00000512484","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005654(nucleoplasm);GO:0051301(cell division);GO:0005694(chromosome);GO:0005829(cytosol);GO:0042803(protein homodimerization activity);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0007049(cell cycle);GO:0048471(perinuclear region of cytoplasm);GO:0005643(nuclear pore);GO:0000922(spindle pole);GO:0042802(identical protein binding);GO:0000775(chromosome, centromeric region);GO:0000776(kinetochore);GO:0000777(condensed chromosome kinetochore);GO:0031145(anaphase-promoting complex-dependent catabolic process);GO:0043161(proteasome-mediated ubiquitin-dependent protein catabolic process);GO:0051437(positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition);GO:0007094(mitotic spindle assembly checkpoint);GO:0007062(sister chromatid cohesion);GO:0043066(negative regulation of apoptotic process);GO:0051436(negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle);GO:0042787(protein ubiquitination involved in ubiquitin-dependent protein catabolic process);GO:0042177(negative regulation of protein catabolic process);GO:0090267(positive regulation of mitotic cell cycle spindle assembly checkpoint);GO:0007093(mitotic cell cycle checkpoint);GO:0072686(mitotic spindle);GO:0045930(negative regulation of mitotic cell cycle);GO:0000070(mitotic sister chromatid segregation);GO:1904667(negative regulation of ubiquitin protein ligase activity);GO:1904667(negative regulation of ubiquitin protein ligase activity)","04110(Cell cycle);04114(Oocyte meiosis);04914(Progesterone-mediated oocyte maturation);05166(HTLV-I infection);05166(HTLV-I infection)","K02537","NA","mitotic arrest deficient 2 like 1 [Source:HGNC Symbol;Acc:HGNC:6763]",{"v":0.435886263395964,"d":"0.44"},{"v":0.470980398051496,"d":"0.47"},{"v":0.925487058907927,"d":"0.93"},{"v":-0.111715277865406,"d":"-0.11"},{"v":0.598503074533821,"d":"0.60"},{"v":0.943580804311874,"d":"0.94"},"down","no"]
["MSTRG.8968","ZNF2","ENST00000617923;ENST00000611147;ENST00000614034","GO:0003676(nucleic acid binding);GO:0046872(metal ion binding);GO:0006355(regulation of transcription, DNA-templated);GO:0005622(intracellular);GO:0005634(nucleus);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0008270(zinc ion binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding)","NA","NA","NA","zinc finger protein 2 [Source:HGNC Symbol;Acc:HGNC:12991]",{"v":0.426978163663664,"d":"0.43"},{"v":0.454145594594595,"d":"0.45"},{"v":0.940179027927855,"d":"0.94"},{"v":-0.088992595425628,"d":"-0.09"},{"v":0.599311579005837,"d":"0.60"},{"v":0.943683560779129,"d":"0.94"},"down","no"]
["ENSG00000074582","BCS1L","ENST00000359273;ENST00000443791;ENST00000436603;ENST00000431802;ENST00000456050;ENST00000493376;ENST00000428880;ENST00000490188;ENST00000471576;ENST00000426649;ENST00000477422;ENST00000430322","GO:0005739(mitochondrion);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0034551(mitochondrial respiratory chain complex III assembly);GO:0005524(ATP binding);GO:0000166(nucleotide binding);GO:0005743(mitochondrial inner membrane);GO:0005515(protein binding);GO:0032981(mitochondrial respiratory chain complex I assembly);GO:0007005(mitochondrion organization);GO:0033617(mitochondrial respiratory chain complex IV assembly);GO:0005750(mitochondrial respiratory chain complex III);GO:0005750(mitochondrial respiratory chain complex III)","NA","NA","NA","BCS1 homolog, ubiquinol-cytochrome c reductase complex chaperone [Source:HGNC Symbol;Acc:HGNC:1020]",{"v":1.34967564752885,"d":"1.35"},{"v":0.879294311334714,"d":"0.88"},{"v":1.534953234805,"d":"1.53"},{"v":0.618194701886871,"d":"0.62"},{"v":0.600790874209578,"d":"0.60"},{"v":0.943683560779129,"d":"0.94"},"up","no"]
["MSTRG.7448","RIOK3","ENST00000577501;ENST00000339486;ENST00000581302;ENST00000584052;ENST00000584130;ENST00000584992;ENST00000581339;ENST00000581220;ENST00000577250","GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0004674(protein serine/threonine kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0005515(protein binding);GO:0002376(immune system process);GO:0045087(innate immune response);GO:0042254(ribosome biogenesis);GO:0051607(defense response to virus);GO:0005829(cytosol);GO:0098586(cellular response to virus);GO:0006364(rRNA processing);GO:0032728(positive regulation of interferon-beta production);GO:0089720(caspase binding);GO:0007059(chromosome segregation);GO:0030490(maturation of SSU-rRNA);GO:0032463(negative regulation of protein homooligomerization);GO:0039534(negative regulation of MDA-5 signaling pathway);GO:0043124(negative regulation of I-kappaB kinase/NF-kappaB signaling);GO:0045089(positive regulation of innate immune response);GO:0071359(cellular response to dsRNA);GO:1990786(cellular response to dsDNA);GO:0030688(preribosome, small subunit precursor);GO:0030688(preribosome, small subunit precursor)","NA","NA","NA","RIO kinase 3 [Source:HGNC Symbol;Acc:HGNC:11451]",{"v":10.7326302302632,"d":"10.73"},{"v":7.02407166597744,"d":"7.02"},{"v":1.52797846329629,"d":"1.53"},{"v":0.611624208874569,"d":"0.61"},{"v":0.602258506375589,"d":"0.60"},{"v":0.943683560779129,"d":"0.94"},"up","no"]
["MSTRG.13645","SEC61G","ENST00000460484;ENST00000395535;ENST00000450622;ENST00000352861;ENST00000480303;ENST00000415949","GO:0005622(intracellular);GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0006886(intracellular protein transport);GO:0015031(protein transport);GO:0015450(P-P-bond-hydrolysis-driven protein transmembrane transporter activity);GO:0006605(protein targeting);GO:0071806(protein transmembrane transport);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005515(protein binding);GO:0005829(cytosol);GO:0045047(protein targeting to ER);GO:0008565(protein transporter activity);GO:0036498(IRE1-mediated unfolded protein response);GO:0036498(IRE1-mediated unfolded protein response)","03060(Protein export);04141(Protein processing in endoplasmic reticulum);04145(Phagosome);05110(Vibrio cholerae infection);05110(Vibrio cholerae infection)","K07342","NA","Sec61 translocon gamma subunit [Source:HGNC Symbol;Acc:HGNC:18277]",{"v":3.71187517535288,"d":"3.71"},{"v":3.90357573018458,"d":"3.90"},{"v":0.950891037325249,"d":"0.95"},{"v":-0.0726480628624453,"d":"-0.07"},{"v":0.603379579628836,"d":"0.60"},{"v":0.943683560779129,"d":"0.94"},"down","no"]
["MSTRG.2478","TMEM179B","ENST00000333449;ENST00000526546;ENST00000533861;ENST00000532586;ENST00000532345;MSTRG.2478.1","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016607(nuclear speck);GO:0005730(nucleolus);GO:0005886(plasma membrane);GO:0043312(neutrophil degranulation);GO:0030667(secretory granule membrane);GO:0035577(azurophil granule membrane);GO:0101003(ficolin-1-rich granule membrane);GO:0101003(ficolin-1-rich granule membrane)","NA","NA","NA","transmembrane protein 179B [Source:HGNC Symbol;Acc:HGNC:33744]",{"v":11.9754501246684,"d":"11.98"},{"v":12.5890271518568,"d":"12.59"},{"v":0.951260965618149,"d":"0.95"},{"v":-0.0720869155728964,"d":"-0.07"},{"v":0.604445891277656,"d":"0.60"},{"v":0.943683560779129,"d":"0.94"},"down","no"]
["ENSG00000143367","TUFT1","ENST00000368848;ENST00000490156;ENST00000392712;ENST00000498606;ENST00000368849","GO:0005515(protein binding);GO:0005576(extracellular region);GO:0005737(cytoplasm);GO:0031214(biomineral tissue development);GO:0030282(bone mineralization);GO:0030345(structural constituent of tooth enamel);GO:0042476(odontogenesis);GO:0042476(odontogenesis)","NA","NA","NA","tuftelin 1 [Source:HGNC Symbol;Acc:HGNC:12422]",{"v":0.463286965188241,"d":"0.46"},{"v":0.489716229757607,"d":"0.49"},{"v":0.946031470955235,"d":"0.95"},{"v":-0.0800399174158765,"d":"-0.08"},{"v":0.604929249347806,"d":"0.60"},{"v":0.943683560779129,"d":"0.94"},"down","no"]
["ENSG00000142173","COL6A2","ENST00000300527;ENST00000409416;ENST00000460886;ENST00000310645;ENST00000485591;ENST00000397763;ENST00000436769;ENST00000413758","GO:0005615(extracellular space);GO:0016020(membrane);GO:0007155(cell adhesion);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0005581(collagen trimer);GO:0005578(proteinaceous extracellular matrix);GO:0070062(extracellular exosome);GO:0031012(extracellular matrix);GO:0030574(collagen catabolic process);GO:0043234(protein complex);GO:0005788(endoplasmic reticulum lumen);GO:0030198(extracellular matrix organization);GO:1903561(extracellular vesicle);GO:0070208(protein heterotrimerization);GO:0009749(response to glucose);GO:0042383(sarcolemma);GO:0042383(sarcolemma)","04151(PI3K-Akt signaling pathway);04512(ECM-receptor interaction);04510(Focal adhesion);04974(Protein digestion and absorption);05165(Human papillomavirus infection);05165(Human papillomavirus infection)","K06238","NA","collagen type VI alpha 2 chain [Source:HGNC Symbol;Acc:HGNC:2212]",{"v":4.17091200297066,"d":"4.17"},{"v":2.7311974528407,"d":"2.73"},{"v":1.5271367504508,"d":"1.53"},{"v":0.610829256871914,"d":"0.61"},{"v":0.605694170437458,"d":"0.61"},{"v":0.943824931374441,"d":"0.94"},"up","no"]
["MSTRG.8171","CEACAM4","MSTRG.8171.1;ENST00000221954;ENST00000472081","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005887(integral component of plasma membrane);GO:0006909(phagocytosis);GO:0006909(phagocytosis)","NA","NA","NA","carcinoembryonic antigen related cell adhesion molecule 4 [Source:HGNC Symbol;Acc:HGNC:1816]",{"v":5.64600170919798,"d":"5.65"},{"v":5.92498116573191,"d":"5.92"},{"v":0.95291470998297,"d":"0.95"},{"v":-0.0695810024636725,"d":"-0.07"},{"v":0.608070232564024,"d":"0.61"},{"v":0.94424341239625,"d":"0.94"},"down","no"]
["MSTRG.1947","SFXN2","ENST00000369893;ENST00000602647;ENST00000602287;ENST00000602660;ENST00000602544;ENST00000602785;ENST00000602831;ENST00000602670;ENST00000459894","GO:0055085(transmembrane transport);GO:0016020(membrane);GO:0006811(ion transport);GO:0034220(ion transmembrane transport);GO:0015075(ion transmembrane transporter activity);GO:0006810(transport);GO:0016021(integral component of membrane);GO:0005739(mitochondrion);GO:0031966(mitochondrial membrane);GO:0055072(iron ion homeostasis);GO:0005743(mitochondrial inner membrane);GO:0005743(mitochondrial inner membrane)","NA","NA","NA","sideroflexin 2 [Source:HGNC Symbol;Acc:HGNC:16086]",{"v":0.320488981578292,"d":"0.32"},{"v":0.204475467388598,"d":"0.20"},{"v":1.56737131192963,"d":"1.57"},{"v":0.648346996288952,"d":"0.65"},{"v":0.60897120071653,"d":"0.61"},{"v":0.94424341239625,"d":"0.94"},"up","no"]
["MSTRG.2860","BUD13","ENST00000260210;ENST00000375445","GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005515(protein binding);GO:0000398(mRNA splicing, via spliceosome);GO:0006406(mRNA export from nucleus);GO:0070274(RES complex);GO:0070274(RES complex)","NA","NA","NA","BUD13 homolog [Source:HGNC Symbol;Acc:HGNC:28199]",{"v":7.127379,"d":"7.13"},{"v":7.462083,"d":"7.46"},{"v":0.955146036301124,"d":"0.96"},{"v":-0.0662067651522984,"d":"-0.07"},{"v":0.61079058411393,"d":"0.61"},{"v":0.944633113645041,"d":"0.94"},"down","no"]
["MSTRG.14621","TIGD5","ENST00000504548","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0003677(DNA binding);GO:0003674(molecular_function);GO:0008150(biological_process);GO:0005575(cellular_component)","NA","NA","NA","tigger transposable element derived 5 [Source:HGNC Symbol;Acc:HGNC:18336]",{"v":0.664055,"d":"0.66"},{"v":0.432451,"d":"0.43"},{"v":1.53556125433864,"d":"1.54"},{"v":0.618766063318658,"d":"0.62"},{"v":0.611124366414996,"d":"0.61"},{"v":0.944633113645041,"d":"0.94"},"up","no"]
["MSTRG.13148","CYB5R4","ENST00000369681;ENST00000369679;ENST00000479164","GO:0046872(metal ion binding);GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0005783(endoplasmic reticulum);GO:0048471(perinuclear region of cytoplasm);GO:0020037(heme binding);GO:0004128(cytochrome-b5 reductase activity, acting on NAD(P)H);GO:0005789(endoplasmic reticulum membrane);GO:0006801(superoxide metabolic process);GO:0016174(NAD(P)H oxidase activity);GO:0042593(glucose homeostasis);GO:0015701(bicarbonate transport);GO:0046677(response to antibiotic);GO:0006091(generation of precursor metabolites and energy);GO:0030073(insulin secretion);GO:0048468(cell development);GO:0016653(oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor);GO:0003032(detection of oxygen);GO:0003032(detection of oxygen)","00520(Amino sugar and nucleotide sugar metabolism);00520(Amino sugar and nucleotide sugar metabolism)","K00326","EC:1.6.2.2","cytochrome b5 reductase 4 [Source:HGNC Symbol;Acc:HGNC:20147]",{"v":7.07693840166061,"d":"7.08"},{"v":7.38856458951738,"d":"7.39"},{"v":0.957823176060626,"d":"0.96"},{"v":-0.062168750581761,"d":"-0.06"},{"v":0.612849462243396,"d":"0.61"},{"v":0.944633113645041,"d":"0.94"},"down","no"]
["ENSG00000164219","PGGT1B","ENST00000419445;ENST00000514178;ENST00000503638;ENST00000296642","GO:0046872(metal ion binding);GO:0016740(transferase activity);GO:0003824(catalytic activity);GO:0008270(zinc ion binding);GO:0018344(protein geranylgeranylation);GO:0004662(CAAX-protein geranylgeranyltransferase activity);GO:0004659(prenyltransferase activity);GO:0004661(protein geranylgeranyltransferase activity);GO:0005953(CAAX-protein geranylgeranyltransferase complex);GO:0008144(drug binding);GO:0019840(isoprenoid binding);GO:0042277(peptide binding);GO:0008284(positive regulation of cell proliferation);GO:0034097(response to cytokine);GO:0045787(positive regulation of cell cycle);GO:0051771(negative regulation of nitric-oxide synthase biosynthetic process);GO:0051771(negative regulation of nitric-oxide synthase biosynthetic process)","NA","NA","NA","protein geranylgeranyltransferase type I subunit beta [Source:HGNC Symbol;Acc:HGNC:8895]",{"v":2.55417854709857,"d":"2.55"},{"v":1.68313635830684,"d":"1.68"},{"v":1.51751136174609,"d":"1.52"},{"v":0.601707318110861,"d":"0.60"},{"v":0.614264939348788,"d":"0.61"},{"v":0.944633113645041,"d":"0.94"},"up","no"]
["ENSG00000009830","POMT2","ENST00000554767;ENST00000556446;ENST00000452340;ENST00000261534;ENST00000555134;ENST00000555710;ENST00000554564","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0046872(metal ion binding);GO:0016740(transferase activity);GO:0016757(transferase activity, transferring glycosyl groups);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0006486(protein glycosylation);GO:0097502(mannosylation);GO:0000030(mannosyltransferase activity);GO:0006493(protein O-linked glycosylation);GO:0071712(ER-associated misfolded protein catabolic process);GO:0035269(protein O-linked mannosylation);GO:0004169(dolichyl-phosphate-mannose-protein mannosyltransferase activity);GO:1904100(positive regulation of protein O-linked glycosylation);GO:1904100(positive regulation of protein O-linked glycosylation)","00515(Mannose type O-glycan biosyntheis);00514(Other types of O-glycan biosynthesis);00514(Other types of O-glycan biosynthesis)","K00728","EC:2.4.1.109","protein O-mannosyltransferase 2 [Source:HGNC Symbol;Acc:HGNC:19743]",{"v":0.240190195243805,"d":"0.24"},{"v":0.156383925559552,"d":"0.16"},{"v":1.53590079277259,"d":"1.54"},{"v":0.61908503220665,"d":"0.62"},{"v":0.61464783435021,"d":"0.61"},{"v":0.944633113645041,"d":"0.94"},"up","no"]
["MSTRG.6918","AC138150.2","ENST00000589796","NA","NA","NA","NA",null,{"v":0.687154879042419,"d":"0.69"},{"v":0.730078185636287,"d":"0.73"},{"v":0.941207246787604,"d":"0.94"},{"v":-0.0874156663095441,"d":"-0.09"},{"v":0.615926539634355,"d":"0.62"},{"v":0.944633113645041,"d":"0.94"},"down","no"]
["ENSG00000178338","ZNF354B","ENST00000322434;ENST00000522714;ENST00000522624;ENST00000520377","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0005622(intracellular);GO:0003682(chromatin binding);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0000122(negative regulation of transcription from RNA polymerase II promoter)","NA","NA","NA","zinc finger protein 354B [Source:HGNC Symbol;Acc:HGNC:17197]",{"v":0.816393259466667,"d":"0.82"},{"v":0.859466622666667,"d":"0.86"},{"v":0.949883611458516,"d":"0.95"},{"v":-0.0741773429788658,"d":"-0.07"},{"v":0.616224432626962,"d":"0.62"},{"v":0.944633113645041,"d":"0.94"},"down","no"]
["ENSG00000247982","LINC00926","ENST00000613170;ENST00000501726;ENST00000502027;ENST00000620766","NA","NA","NA","NA","long intergenic non-protein coding RNA 926 [Source:HGNC Symbol;Acc:HGNC:27514]",{"v":2.74803745352957,"d":"2.75"},{"v":1.81423955737258,"d":"1.81"},{"v":1.51470484829982,"d":"1.51"},{"v":0.599036701039486,"d":"0.60"},{"v":0.618455611355022,"d":"0.62"},{"v":0.945638579942841,"d":"0.95"},"up","no"]
["MSTRG.7300","GAA","ENST00000390015;MSTRG.7300.1;ENST00000574376;ENST00000572080;ENST00000572803;ENST00000577106;ENST00000573556;ENST00000570716;ENST00000302262","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0030246(carbohydrate binding);GO:0003824(catalytic activity);GO:0005975(carbohydrate metabolic process);GO:0016787(hydrolase activity);GO:0005765(lysosomal membrane);GO:0008152(metabolic process);GO:0004553(hydrolase activity, hydrolyzing O-glycosyl compounds);GO:0016798(hydrolase activity, acting on glycosyl bonds);GO:0005764(lysosome);GO:0005886(plasma membrane);GO:0070062(extracellular exosome);GO:0043312(neutrophil degranulation);GO:0070821(tertiary granule membrane);GO:0035577(azurophil granule membrane);GO:0043202(lysosomal lumen);GO:0060048(cardiac muscle contraction);GO:0101003(ficolin-1-rich granule membrane);GO:0005980(glycogen catabolic process);GO:0004558(alpha-1,4-glucosidase activity);GO:0032450(maltose alpha-glucosidase activity);GO:0007040(lysosome organization);GO:0004574(oligo-1,6-glucosidase activity);GO:0000023(maltose metabolic process);GO:0002086(diaphragm contraction);GO:0005985(sucrose metabolic process);GO:0006006(glucose metabolic process);GO:0043181(vacuolar sequestering);GO:0002026(regulation of the force of heart contraction);GO:0003007(heart morphogenesis);GO:0005977(glycogen metabolic process);GO:0006941(striated muscle contraction);GO:0007626(locomotory behavior);GO:0009888(tissue development);GO:0046716(muscle cell cellular homeostasis);GO:0050884(neuromuscular process controlling posture);GO:0050885(neuromuscular process controlling balance);GO:0050885(neuromuscular process controlling balance)","00052(Galactose metabolism);00500(Starch and sucrose metabolism);04142(Lysosome);04142(Lysosome)","K12316","EC:3.2.1.20","glucosidase alpha, acid [Source:HGNC Symbol;Acc:HGNC:4065]",{"v":12.2370236103595,"d":"12.24"},{"v":8.09990831194434,"d":"8.10"},{"v":1.51076075667603,"d":"1.51"},{"v":0.595275214119609,"d":"0.60"},{"v":0.619170222151175,"d":"0.62"},{"v":0.945888542641895,"d":"0.95"},"up","no"]
["MSTRG.1456","GALNT2","ENST00000366672;ENST00000485438;ENST00000494106;ENST00000488903;ENST00000492568","GO:0048471(perinuclear region of cytoplasm);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005794(Golgi apparatus);GO:0046872(metal ion binding);GO:0016740(transferase activity);GO:0030246(carbohydrate binding);GO:0016757(transferase activity, transferring glycosyl groups);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0000139(Golgi membrane);GO:0006486(protein glycosylation);GO:0032580(Golgi cisterna membrane);GO:0005789(endoplasmic reticulum membrane);GO:0070062(extracellular exosome);GO:0006493(protein O-linked glycosylation);GO:0016266(O-glycan processing);GO:0030145(manganese ion binding);GO:0004653(polypeptide N-acetylgalactosaminyltransferase activity);GO:0002378(immunoglobulin biosynthetic process);GO:0018242(protein O-linked glycosylation via serine);GO:0018243(protein O-linked glycosylation via threonine);GO:0005795(Golgi stack);GO:0030173(integral component of Golgi membrane);GO:0030173(integral component of Golgi membrane)","00512(Mucin type O-glycan biosynthesis);00512(Mucin type O-glycan biosynthesis)","K00710","EC:2.4.1.41","polypeptide N-acetylgalactosaminyltransferase 2 [Source:HGNC Symbol;Acc:HGNC:4124]",{"v":4.82364479633217,"d":"4.82"},{"v":3.1970607222007,"d":"3.20"},{"v":1.50877484523091,"d":"1.51"},{"v":0.593377528260357,"d":"0.59"},{"v":0.621226005975421,"d":"0.62"},{"v":0.946746569382501,"d":"0.95"},"up","no"]
["MSTRG.12315","TXNDC15","ENST00000358387;ENST00000505174;ENST00000506350;ENST00000509954;ENST00000508810;ENST00000508779;ENST00000507024;ENST00000502625;ENST00000506916;ENST00000511070","GO:0005623(cell);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0045454(cell redox homeostasis);GO:0045454(cell redox homeostasis)","NA","NA","NA","thioredoxin domain containing 15 [Source:HGNC Symbol;Acc:HGNC:20652]",{"v":3.60802268964862,"d":"3.61"},{"v":3.75417958290598,"d":"3.75"},{"v":0.961068220091852,"d":"0.96"},{"v":-0.0572892525511991,"d":"-0.06"},{"v":0.621926575190265,"d":"0.62"},{"v":0.946746569382501,"d":"0.95"},"down","no"]
["ENSG00000166845","C18orf54","ENST00000620105","GO:0005515(protein binding);GO:0005576(extracellular region);GO:0008285(negative regulation of cell proliferation)","NA","NA","NA","chromosome 18 open reading frame 54 [Source:HGNC Symbol;Acc:HGNC:13796]",{"v":0.340794888155724,"d":"0.34"},{"v":0.221695487462884,"d":"0.22"},{"v":1.53722068074471,"d":"1.54"},{"v":0.620324290703525,"d":"0.62"},{"v":0.623594033272936,"d":"0.62"},{"v":0.94735097695263,"d":"0.95"},"up","no"]
["MSTRG.5481","AXIN1","ENST00000262320;ENST00000354866;ENST00000461023;MSTRG.5481.1;ENST00000457798;ENST00000481769","GO:0048471(perinuclear region of cytoplasm);GO:0005737(cytoplasm);GO:0001934(positive regulation of protein phosphorylation);GO:0005634(nucleus);GO:0016020(membrane);GO:0007165(signal transduction);GO:0042803(protein homodimerization activity);GO:0005886(plasma membrane);GO:0043547(positive regulation of GTPase activity);GO:0005515(protein binding);GO:0006915(apoptotic process);GO:0007275(multicellular organism development);GO:0016055(Wnt signaling pathway);GO:0030159(receptor signaling complex scaffold activity);GO:0005096(GTPase activator activity);GO:0030877(beta-catenin destruction complex);GO:0005829(cytosol);GO:0016579(protein deubiquitination);GO:0043161(proteasome-mediated ubiquitin-dependent protein catabolic process);GO:0090263(positive regulation of canonical Wnt signaling pathway);GO:0032947(protein complex scaffold);GO:0070016(armadillo repeat domain binding);GO:0031122(cytoplasmic microtubule organization);GO:0031625(ubiquitin protein ligase binding);GO:0033138(positive regulation of peptidyl-serine phosphorylation);GO:0019899(enzyme binding);GO:0045893(positive regulation of transcription, DNA-templated);GO:0031410(cytoplasmic vesicle);GO:0019901(protein kinase binding);GO:0042802(identical protein binding);GO:1904886(beta-catenin destruction complex disassembly);GO:0008013(beta-catenin binding);GO:0070411(I-SMAD binding);GO:0031398(positive regulation of protein ubiquitination);GO:0004871(signal transducer activity);GO:0046332(SMAD binding);GO:0001743(optic placode formation);GO:0007257(activation of JUN kinase activity);GO:0007368(determination of left/right symmetry);GO:0010800(positive regulation of peptidyl-threonine phosphorylation);GO:0021797(forebrain anterior/posterior pattern specification);GO:0021881(Wnt-activated signaling pathway involved in forebrain neuron fate commitment);GO:0030111(regulation of Wnt signaling pathway);GO:0030178(negative regulation of Wnt signaling pathway);GO:0030910(olfactory placode formation);GO:0032147(activation of protein kinase activity);GO:0033146(regulation of intracellular estrogen receptor signaling pathway);GO:0034244(negative regulation of transcription elongation from RNA polymerase II promoter);GO:0043623(cellular protein complex assembly);GO:0045599(negative regulation of fat cell differentiation);GO:0045732(positive regulation of protein catabolic process);GO:0046330(positive regulation of JNK cascade);GO:0048048(embryonic eye morphogenesis);GO:0048320(axial mesoderm formation);GO:0051443(positive regulation of ubiquitin-protein transferase activity);GO:0055001(muscle cell development);GO:0060070(canonical Wnt signaling pathway);GO:0060272(embryonic skeletal joint morphogenesis);GO:0060823(canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation);GO:0090090(negative regulation of canonical Wnt signaling pathway);GO:1904885(beta-catenin destruction complex assembly);GO:2000060(positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process);GO:0016328(lateral plasma membrane);GO:0071944(cell periphery);GO:0071944(cell periphery)","04310(Wnt signaling pathway);04390(Hippo signaling pathway);04550(Signaling pathways regulating pluripotency of stem cells);05200(Pathways in cancer);05210(Colorectal cancer);05225(Hepatocellular carcinoma);05226(Gastric cancer);05217(Basal cell carcinoma);05213(Endometrial cancer);05224(Breast cancer);05165(Human papillomavirus infection);05165(Human papillomavirus infection)","K02157","NA","axin 1 [Source:HGNC Symbol;Acc:HGNC:903]",{"v":7.23615568339369,"d":"7.24"},{"v":4.80956468054837,"d":"4.81"},{"v":1.50453443586263,"d":"1.50"},{"v":0.589317127528479,"d":"0.59"},{"v":0.625425090511464,"d":"0.63"},{"v":0.947932860364086,"d":"0.95"},"up","no"]
["MSTRG.15465","ARHGEF6","ENST00000370620;ENST00000250617","GO:0005089(Rho guanyl-nucleotide exchange factor activity);GO:0035023(regulation of Rho protein signal transduction);GO:0043547(positive regulation of GTPase activity);GO:0042995(cell projection);GO:0005515(protein binding);GO:0006915(apoptotic process);GO:0005096(GTPase activator activity);GO:0005085(guanyl-nucleotide exchange factor activity);GO:0005829(cytosol);GO:0030027(lamellipodium);GO:0051056(regulation of small GTPase mediated signal transduction);GO:0005622(intracellular);GO:0030032(lamellipodium assembly);GO:0043065(positive regulation of apoptotic process);GO:0007254(JNK cascade);GO:0007254(JNK cascade)","04810(Regulation of actin cytoskeleton);05212(Pancreatic cancer);05212(Pancreatic cancer)","K05729","NA","Rac/Cdc42 guanine nucleotide exchange factor 6 [Source:HGNC Symbol;Acc:HGNC:685]",{"v":18.5382566576003,"d":"18.54"},{"v":12.3275545612372,"d":"12.33"},{"v":1.50380649832141,"d":"1.50"},{"v":0.588618940770884,"d":"0.59"},{"v":0.625914963220606,"d":"0.63"},{"v":0.948169797954915,"d":"0.95"},"up","no"]
["MSTRG.3313","SLC38A2","ENST00000256689;ENST00000551405;ENST00000548785;ENST00000553252;ENST00000548870;ENST00000547252;ENST00000546520;ENST00000548236;ENST00000549258;ENST00000552703;ENST00000552414;ENST00000551374","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0015293(symporter activity);GO:0006811(ion transport);GO:0005886(plasma membrane);GO:0015171(amino acid transmembrane transporter activity);GO:0003333(amino acid transmembrane transport);GO:0006865(amino acid transport);GO:0007565(female pregnancy);GO:0021987(cerebral cortex development);GO:0031460(glycine betaine transport);GO:0032328(alanine transport);GO:0034198(cellular response to amino acid starvation);GO:0071260(cellular response to mechanical stimulus);GO:0005903(brush border);GO:0030424(axon);GO:0030425(dendrite);GO:0042383(sarcolemma);GO:0043025(neuronal cell body);GO:0005515(protein binding);GO:0006814(sodium ion transport);GO:0005887(integral component of plasma membrane);GO:0014047(glutamate secretion);GO:0014047(glutamate secretion)","04974(Protein digestion and absorption);04724(Glutamatergic synapse);04727(GABAergic synapse);04727(GABAergic synapse)","K14207","NA","solute carrier family 38 member 2 [Source:HGNC Symbol;Acc:HGNC:13448]",{"v":7.20132490366556,"d":"7.20"},{"v":4.79400088851863,"d":"4.79"},{"v":1.50215343533046,"d":"1.50"},{"v":0.587032182415901,"d":"0.59"},{"v":0.62795138430602,"d":"0.63"},{"v":0.948728677240204,"d":"0.95"},"up","no"]
["ENSG00000093217","XYLB","ENST00000207870;ENST00000487569;ENST00000472721","GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0016773(phosphotransferase activity, alcohol group as acceptor);GO:0005975(carbohydrate metabolic process);GO:0005737(cytoplasm);GO:0046835(carbohydrate phosphorylation);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0006091(generation of precursor metabolites and energy);GO:0004856(xylulokinase activity);GO:0005997(xylulose metabolic process);GO:0005998(xylulose catabolic process);GO:0019640(glucuronate catabolic process to xylulose 5-phosphate);GO:0042732(D-xylose metabolic process);GO:0042732(D-xylose metabolic process)","00040(Pentose and glucuronate interconversions);00040(Pentose and glucuronate interconversions)","K00854","EC:2.7.1.17","xylulokinase [Source:HGNC Symbol;Acc:HGNC:12839]",{"v":0.154669443196706,"d":"0.15"},{"v":0.170143185476324,"d":"0.17"},{"v":0.909054586956871,"d":"0.91"},{"v":-0.137561166840405,"d":"-0.14"},{"v":0.628919636356463,"d":"0.63"},{"v":0.948920948099036,"d":"0.95"},"down","no"]
["MSTRG.2126","NAP1L4","ENST00000380542;MSTRG.2126.2;ENST00000620138;ENST00000531291;ENST00000399614;ENST00000455338;ENST00000532325;ENST00000492594;ENST00000448187;ENST00000528363;ENST00000528261;ENST00000526115;ENST00000469089;ENST00000529361;ENST00000526842;ENST00000430811;ENST00000530064;ENST00000483643;ENST00000528968;ENST00000492685;ENST00000469805;ENST00000534372","GO:0005634(nucleus);GO:0003723(RNA binding);GO:0005737(cytoplasm);GO:0006334(nucleosome assembly);GO:0005515(protein binding);GO:0051082(unfolded protein binding);GO:0031491(nucleosome binding);GO:0031491(nucleosome binding)","NA","NA","NA","nucleosome assembly protein 1 like 4 [Source:HGNC Symbol;Acc:HGNC:7640]",{"v":11.6525342826923,"d":"11.65"},{"v":12.0305149990385,"d":"12.03"},{"v":0.968581501591876,"d":"0.97"},{"v":-0.046054644927908,"d":"-0.05"},{"v":0.63009006705895,"d":"0.63"},{"v":0.949057840305524,"d":"0.95"},"down","no"]
["MSTRG.9965","GABPA","ENST00000400075;ENST00000354828","GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0006355(regulation of transcription, DNA-templated);GO:0006366(transcription from RNA polymerase II promoter);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0043565(sequence-specific DNA binding);GO:0005515(protein binding);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:0001228(transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding);GO:0003682(chromatin binding);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0001701(in utero embryonic development);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0045653(negative regulation of megakaryocyte differentiation);GO:0030154(cell differentiation);GO:0003713(transcription coactivator activity);GO:0000790(nuclear chromatin);GO:0007005(mitochondrion organization);GO:0001077(transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0046982(protein heterodimerization activity);GO:0010628(positive regulation of gene expression);GO:1903351(cellular response to dopamine);GO:0044212(transcription regulatory region DNA binding);GO:0033613(activating transcription factor binding);GO:0033613(activating transcription factor binding)","NA","NA","NA","GA binding protein transcription factor alpha subunit [Source:HGNC Symbol;Acc:HGNC:4071]",{"v":7.54232368465648,"d":"7.54"},{"v":5.03293298802726,"d":"5.03"},{"v":1.49859410061663,"d":"1.50"},{"v":0.58360967726527,"d":"0.58"},{"v":0.632353760125565,"d":"0.63"},{"v":0.949676800234658,"d":"0.95"},"up","no"]
["MSTRG.1786","NUDT13","ENST00000469925;ENST00000488223;ENST00000544879","GO:0016787(hydrolase activity);GO:0046872(metal ion binding);GO:0005759(mitochondrial matrix);GO:0015949(nucleobase-containing small molecule interconversion);GO:0016462(pyrophosphatase activity);GO:0005739(mitochondrion);GO:0005739(mitochondrion)","NA","NA","NA","nudix hydrolase 13 [Source:HGNC Symbol;Acc:HGNC:18827]",{"v":0.48370399603332,"d":"0.48"},{"v":0.318149372074574,"d":"0.32"},{"v":1.52036759613638,"d":"1.52"},{"v":0.604420182225483,"d":"0.60"},{"v":0.632455187920973,"d":"0.63"},{"v":0.949676800234658,"d":"0.95"},"up","no"]
["MSTRG.14208","XPO7","ENST00000252512;ENST00000518808;ENST00000521303;ENST00000517551;ENST00000522015;ENST00000520754;ENST00000433566;ENST00000519769","GO:0006810(transport);GO:0051028(mRNA transport);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0006886(intracellular protein transport);GO:0015031(protein transport);GO:0005515(protein binding);GO:0008536(Ran GTPase binding);GO:0005643(nuclear pore);GO:0006611(protein export from nucleus);GO:0005049(nuclear export signal receptor activity);GO:0005622(intracellular);GO:0005622(intracellular)","NA","NA","NA","exportin 7 [Source:HGNC Symbol;Acc:HGNC:14108]",{"v":10.8237845151252,"d":"10.82"},{"v":7.23578444434795,"d":"7.24"},{"v":1.49586884440428,"d":"1.50"},{"v":0.580983687376317,"d":"0.58"},{"v":0.63417893743489,"d":"0.63"},{"v":0.950556661638301,"d":"0.95"},"up","no"]
["MSTRG.7556","CNDP2","ENST00000579847;ENST00000324262;ENST00000584581;ENST00000577669;ENST00000582620;ENST00000583785;ENST00000585263;ENST00000577355;ENST00000583216;ENST00000583203;ENST00000579624;ENST00000581513;ENST00000580672;ENST00000583399;ENST00000583938;ENST00000582666;ENST00000580229;ENST00000583695;ENST00000582260;ENST00000577409;ENST00000581272;ENST00000582589;ENST00000584768;ENST00000581912;ENST00000324301","GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0008152(metabolic process);GO:0016787(hydrolase activity);GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0008233(peptidase activity);GO:0006508(proteolysis);GO:0008237(metallopeptidase activity);GO:0004180(carboxypeptidase activity);GO:0016805(dipeptidase activity);GO:0070062(extracellular exosome);GO:0006750(glutathione biosynthetic process);GO:0102008(cytosolic dipeptidase activity);GO:0103046(alanylglutamate dipeptidase activity);GO:0103046(alanylglutamate dipeptidase activity)","00330(Arginine and proline metabolism);00340(Histidine metabolism);00410(beta-Alanine metabolism);00410(beta-Alanine metabolism)","K08660","EC:3.4.13.18","carnosine dipeptidase 2 [Source:HGNC Symbol;Acc:HGNC:24437]",{"v":3.75849578941593,"d":"3.76"},{"v":3.86589648522957,"d":"3.87"},{"v":0.972218424310122,"d":"0.97"},{"v":-0.0406476202867057,"d":"-0.04"},{"v":0.63554872850954,"d":"0.64"},{"v":0.950556661638301,"d":"0.95"},"down","no"]
["ENSG00000169490","TM2D2","ENST00000397070;ENST00000456397;ENST00000519186;ENST00000517872;ENST00000522434;ENST00000524331;ENST00000522142","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016021(integral component of membrane)","NA","NA","NA","TM2 domain containing 2 [Source:HGNC Symbol;Acc:HGNC:24127]",{"v":2.18282903117291,"d":"2.18"},{"v":2.25104841332137,"d":"2.25"},{"v":0.969694395844733,"d":"0.97"},{"v":-0.0443979486875144,"d":"-0.04"},{"v":0.636756025047215,"d":"0.64"},{"v":0.950556661638301,"d":"0.95"},"down","no"]
["ENSG00000155893","PXYLP1","ENST00000286353;ENST00000636601;ENST00000637751;ENST00000505013;ENST00000513007;ENST00000508812;ENST00000502783;ENST00000511968;ENST00000512457;ENST00000505502;ENST00000393010","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016787(hydrolase activity);GO:0005794(Golgi apparatus);GO:0016311(dephosphorylation);GO:0000139(Golgi membrane);GO:0003993(acid phosphatase activity);GO:0005515(protein binding);GO:0016791(phosphatase activity);GO:0006024(glycosaminoglycan biosynthetic process);GO:0050650(chondroitin sulfate proteoglycan biosynthetic process);GO:0010909(positive regulation of heparan sulfate proteoglycan biosynthetic process);GO:0010909(positive regulation of heparan sulfate proteoglycan biosynthetic process)","NA","NA","NA","2-phosphoxylose phosphatase 1 [Source:HGNC Symbol;Acc:HGNC:26303]",{"v":0.454419688330206,"d":"0.45"},{"v":0.468396666116323,"d":"0.47"},{"v":0.970159954591466,"d":"0.97"},{"v":-0.0437054644214672,"d":"-0.04"},{"v":0.637276595303443,"d":"0.64"},{"v":0.950556661638301,"d":"0.95"},"down","no"]
["MSTRG.8388","PPP2R1A","ENST00000322088;ENST00000477989;ENST00000391791;ENST00000468280;ENST00000473820;ENST00000462990;ENST00000473455;ENST00000454220;ENST00000462047;ENST00000495876;ENST00000490868","GO:0008380(RNA splicing);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0006355(regulation of transcription, DNA-templated);GO:0005694(chromosome);GO:0005829(cytosol);GO:0005739(mitochondrion);GO:0005886(plasma membrane);GO:0050790(regulation of catalytic activity);GO:0042995(cell projection);GO:0005515(protein binding);GO:0006915(apoptotic process);GO:0019888(protein phosphatase regulator activity);GO:0030425(dendrite);GO:0003823(antigen binding);GO:0007059(chromosome segregation);GO:0000775(chromosome, centromeric region);GO:0006461(protein complex assembly);GO:0000159(protein phosphatase type 2A complex);GO:0015630(microtubule cytoskeleton);GO:0070062(extracellular exosome);GO:0040008(regulation of growth);GO:0004722(protein serine/threonine phosphatase activity);GO:0007143(female meiotic nuclear division);GO:0051232(meiotic spindle elongation);GO:0051306(mitotic sister chromatid separation);GO:0051754(meiotic sister chromatid cohesion, centromeric);GO:0070262(peptidyl-serine dephosphorylation);GO:1903538(regulation of meiotic cell cycle process involved in oocyte maturation);GO:2001241(positive regulation of extrinsic apoptotic signaling pathway in absence of ligand);GO:0000086(G2/M transition of mitotic cell cycle);GO:0010389(regulation of G2/M transition of mitotic cell cycle);GO:0097711(ciliary basal body docking);GO:0016328(lateral plasma membrane);GO:0030308(negative regulation of cell growth);GO:0046982(protein heterodimerization activity);GO:0010033(response to organic substance);GO:0030155(regulation of cell adhesion);GO:0006470(protein dephosphorylation);GO:0000184(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay);GO:0042532(negative regulation of tyrosine phosphorylation of STAT protein);GO:0045595(regulation of cell differentiation);GO:0030111(regulation of Wnt signaling pathway);GO:0006275(regulation of DNA replication);GO:0007084(mitotic nuclear envelope reassembly);GO:0006672(ceramide metabolic process);GO:0000188(inactivation of MAPK activity);GO:0019932(second-messenger-mediated signaling);GO:0019932(second-messenger-mediated signaling)","03015(mRNA surveillance pathway);04350(TGF-beta signaling pathway);04390(Hippo signaling pathway);04071(Sphingolipid signaling pathway);04151(PI3K-Akt signaling pathway);04152(AMPK signaling pathway);04114(Oocyte meiosis);04530(Tight junction);04261(Adrenergic signaling in cardiomyocytes);04728(Dopaminergic synapse);04730(Long-term depression);05160(Hepatitis C);05165(Human papillomavirus infection);05142(Chagas disease (American trypanosomiasis));05142(Chagas disease (American trypanosomiasis))","K03456","NA","protein phosphatase 2 scaffold subunit Aalpha [Source:HGNC Symbol;Acc:HGNC:9302]",{"v":9.8937864011026,"d":"9.89"},{"v":10.1546494175071,"d":"10.15"},{"v":0.974310977594681,"d":"0.97"},{"v":-0.0375457740917025,"d":"-0.04"},{"v":0.639382178966496,"d":"0.64"},{"v":0.95108815733802,"d":"0.95"},"down","no"]
["MSTRG.1697","WASHC2C","ENST00000336378;ENST00000540872;ENST00000623400;ENST00000471102;ENST00000359860;ENST00000374359;ENST00000537517;ENST00000374362;ENST00000420848;ENST00000485850","GO:0006810(transport);GO:0016020(membrane);GO:0015031(protein transport);GO:0043231(intracellular membrane-bounded organelle);GO:0005730(nucleolus);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0008289(lipid binding);GO:0071203(WASH complex);GO:0005515(protein binding);GO:0005768(endosome);GO:0010314(phosphatidylinositol-5-phosphate binding);GO:0032266(phosphatidylinositol-3-phosphate binding);GO:0080025(phosphatidylinositol-3,5-bisphosphate binding);GO:0005769(early endosome);GO:0042147(retrograde transport, endosome to Golgi);GO:1990126(retrograde transport, endosome to plasma membrane);GO:0031901(early endosome membrane);GO:0005546(phosphatidylinositol-4,5-bisphosphate binding);GO:0005547(phosphatidylinositol-3,4,5-trisphosphate binding);GO:0043325(phosphatidylinositol-3,4-bisphosphate binding);GO:0030904(retromer complex);GO:0070273(phosphatidylinositol-4-phosphate binding);GO:1905394(retromer complex binding);GO:1900024(regulation of substrate adhesion-dependent cell spreading);GO:2000813(negative regulation of barbed-end actin filament capping);GO:2000813(negative regulation of barbed-end actin filament capping)","04144(Endocytosis);04144(Endocytosis)","K18462","NA","WASH complex subunit 2C [Source:HGNC Symbol;Acc:HGNC:23414]",{"v":11.7017503593476,"d":"11.70"},{"v":7.85234113626798,"d":"7.85"},{"v":1.49022440012192,"d":"1.49"},{"v":0.575529590128479,"d":"0.58"},{"v":0.640735944490318,"d":"0.64"},{"v":0.951193714038743,"d":"0.95"},"up","no"]
["ENSG00000174099","MSRB3","ENST00000355192;ENST00000614640;ENST00000540804;ENST00000308259","GO:0046872(metal ion binding);GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0005783(endoplasmic reticulum);GO:0005739(mitochondrion);GO:0005515(protein binding);GO:0006979(response to oxidative stress);GO:0016671(oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor);GO:0033743(peptide-methionine (R)-S-oxide reductase activity);GO:0030091(protein repair);GO:0005829(cytosol);GO:0008270(zinc ion binding);GO:0008270(zinc ion binding)","NA","NA","NA","methionine sulfoxide reductase B3 [Source:HGNC Symbol;Acc:HGNC:27375]",{"v":1.13269446002418,"d":"1.13"},{"v":0.754520952167156,"d":"0.75"},{"v":1.5012100814044,"d":"1.50"},{"v":0.586125883815606,"d":"0.59"},{"v":0.641243026308817,"d":"0.64"},{"v":0.951193714038743,"d":"0.95"},"up","no"]
["ENSG00000179222","MAGED1","ENST00000375772;ENST00000326587;ENST00000470461;ENST00000482188;ENST00000375722;ENST00000482599;ENST00000473931;ENST00000375695;ENST00000494718","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0006355(regulation of transcription, DNA-templated);GO:0042981(regulation of apoptotic process);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0048511(rhythmic process);GO:0042802(identical protein binding);GO:0032922(circadian regulation of gene expression);GO:0043234(protein complex);GO:0000785(chromatin);GO:0050680(negative regulation of epithelial cell proliferation);GO:0003713(transcription coactivator activity);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0042752(regulation of circadian rhythm);GO:0043406(positive regulation of MAP kinase activity);GO:0045892(negative regulation of transcription, DNA-templated);GO:0045893(positive regulation of transcription, DNA-templated);GO:0090190(positive regulation of branching involved in ureteric bud morphogenesis);GO:2001235(positive regulation of apoptotic signaling pathway);GO:2001235(positive regulation of apoptotic signaling pathway)","04722(Neurotrophin signaling pathway);04722(Neurotrophin signaling pathway)","K12464","NA","MAGE family member D1 [Source:HGNC Symbol;Acc:HGNC:6813]",{"v":2.48411116855053,"d":"2.48"},{"v":1.66948496343085,"d":"1.67"},{"v":1.48795060929785,"d":"1.49"},{"v":0.573326638741865,"d":"0.57"},{"v":0.643246708455814,"d":"0.64"},{"v":0.951931998947156,"d":"0.95"},"up","no"]
["MSTRG.14476","MATN2","ENST00000518370;ENST00000523561;ENST00000523490;ENST00000254898;ENST00000522135;ENST00000520160","GO:0005509(calcium ion binding);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0005578(proteinaceous extracellular matrix);GO:0003674(molecular_function);GO:0008150(biological_process);GO:0031012(extracellular matrix);GO:0001764(neuron migration);GO:0007411(axon guidance);GO:0008347(glial cell migration);GO:0031104(dendrite regeneration);GO:0031175(neuron projection development);GO:0048678(response to axon injury);GO:0005604(basement membrane);GO:0005615(extracellular space);GO:0005615(extracellular space)","NA","NA","NA","matrilin 2 [Source:HGNC Symbol;Acc:HGNC:6908]",{"v":0.144716445838742,"d":"0.14"},{"v":0.15199890956296,"d":"0.15"},{"v":0.9520887107338,"d":"0.95"},{"v":-0.0708320921806523,"d":"-0.07"},{"v":0.644412651194914,"d":"0.64"},{"v":0.952182588810504,"d":"0.95"},"down","no"]
["ENSG00000092758","COL9A3","ENST00000466192;ENST00000462700;ENST00000343916;ENST00000463487;ENST00000466532;ENST00000469802;ENST00000467819;ENST00000472880","GO:0005576(extracellular region);GO:0005581(collagen trimer);GO:0005578(proteinaceous extracellular matrix);GO:0005788(endoplasmic reticulum lumen);GO:0030198(extracellular matrix organization);GO:0030020(extracellular matrix structural constituent conferring tensile strength);GO:0005594(collagen type IX trimer);GO:0008584(male gonad development);GO:0008585(female gonad development);GO:0008585(female gonad development)","04151(PI3K-Akt signaling pathway);04512(ECM-receptor interaction);04510(Focal adhesion);04974(Protein digestion and absorption);05165(Human papillomavirus infection);05165(Human papillomavirus infection)","K08131","NA","collagen type IX alpha 3 chain [Source:HGNC Symbol;Acc:HGNC:2219]",{"v":0.28787691057752,"d":"0.29"},{"v":0.189828369695715,"d":"0.19"},{"v":1.51651152585344,"d":"1.52"},{"v":0.6007564628341,"d":"0.60"},{"v":0.64586030756299,"d":"0.65"},{"v":0.952250202978923,"d":"0.95"},"up","no"]
["ENSG00000114544","SLC41A3","ENST00000315891;ENST00000360370;ENST00000346785;ENST00000514677;ENST00000506102;ENST00000512470;ENST00000512557;ENST00000383598;ENST00000504035;ENST00000507280;ENST00000514891;ENST00000510651;ENST00000514333;ENST00000509064","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0098655(cation transmembrane transport);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0006812(cation transport);GO:0055085(transmembrane transport);GO:0008324(cation transmembrane transporter activity);GO:0008324(cation transmembrane transporter activity)","NA","NA","NA","solute carrier family 41 member 3 [Source:HGNC Symbol;Acc:HGNC:31046]",{"v":1.81498204065534,"d":"1.81"},{"v":1.86037822663835,"d":"1.86"},{"v":0.975598410402255,"d":"0.98"},{"v":-0.0356406874160905,"d":"-0.04"},{"v":0.647147656437724,"d":"0.65"},{"v":0.952250202978923,"d":"0.95"},"down","no"]
["MSTRG.1083","GPATCH4","ENST00000368232;ENST00000527691;ENST00000438976;ENST00000529520;ENST00000531129;ENST00000494414;ENST00000498641;ENST00000498756;ENST00000473910;ENST00000415314;ENST00000531900;ENST00000525375;ENST00000506832","GO:0003676(nucleic acid binding);GO:0002244(hematopoietic progenitor cell differentiation);GO:0002244(hematopoietic progenitor cell differentiation)","NA","NA","NA","G-patch domain containing 4 [Source:HGNC Symbol;Acc:HGNC:25982]",{"v":0.80245799459094,"d":"0.80"},{"v":0.828992748929457,"d":"0.83"},{"v":0.967991572456112,"d":"0.97"},{"v":-0.0469336077477203,"d":"-0.05"},{"v":0.647384969946426,"d":"0.65"},{"v":0.952250202978923,"d":"0.95"},"down","no"]
["MSTRG.807","ST7L","ENST00000479436;ENST00000369664;ENST00000369669;ENST00000490715;ENST00000369666;ENST00000361846;ENST00000358039;ENST00000473206;ENST00000470519;ENST00000477332;ENST00000470683;ENST00000497457;ENST00000463235;ENST00000498197;ENST00000459630;ENST00000485753","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0030308(negative regulation of cell growth);GO:0030308(negative regulation of cell growth)","NA","NA","NA","suppression of tumorigenicity 7 like [Source:HGNC Symbol;Acc:HGNC:18441]",{"v":0.254115403156208,"d":"0.25"},{"v":0.267190203674023,"d":"0.27"},{"v":0.951065569253555,"d":"0.95"},{"v":-0.0723832867394988,"d":"-0.07"},{"v":0.649564205310712,"d":"0.65"},{"v":0.952261504625307,"d":"0.95"},"down","no"]
["ENSG00000179542","SLITRK4","ENST00000596188;ENST00000338017","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005886(plasma membrane);GO:0007409(axonogenesis);GO:0051965(positive regulation of synapse assembly);GO:0051965(positive regulation of synapse assembly)","NA","NA","NA","SLIT and NTRK like family member 4 [Source:HGNC Symbol;Acc:HGNC:23502]",{"v":0.165099484518735,"d":"0.17"},{"v":0.170519731209334,"d":"0.17"},{"v":0.968213375354521,"d":"0.97"},{"v":-0.0466030704837273,"d":"-0.05"},{"v":0.649763017122949,"d":"0.65"},{"v":0.952261504625307,"d":"0.95"},"down","no"]
["MSTRG.1728","UBE2D1","ENST00000373910;ENST00000473824;ENST00000606483;ENST00000615793","GO:0005737(cytoplasm);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0016740(transferase activity);GO:0016567(protein ubiquitination);GO:0004842(ubiquitin-protein transferase activity);GO:0061631(ubiquitin conjugating enzyme activity);GO:0000209(protein polyubiquitination);GO:1902916(positive regulation of protein polyubiquitination);GO:0005515(protein binding);GO:0006511(ubiquitin-dependent protein catabolic process);GO:0038095(Fc-epsilon receptor signaling pathway);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0002223(stimulatory C-type lectin receptor signaling pathway);GO:0016579(protein deubiquitination);GO:0031145(anaphase-promoting complex-dependent catabolic process);GO:0043161(proteasome-mediated ubiquitin-dependent protein catabolic process);GO:0050852(T cell receptor signaling pathway);GO:0051437(positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition);GO:0061418(regulation of transcription from RNA polymerase II promoter in response to hypoxia);GO:0031398(positive regulation of protein ubiquitination);GO:0043234(protein complex);GO:0035666(TRIF-dependent toll-like receptor signaling pathway);GO:0051436(negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle);GO:0030509(BMP signaling pathway);GO:0042787(protein ubiquitination involved in ubiquitin-dependent protein catabolic process);GO:0051439(regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle);GO:0070936(protein K48-linked ubiquitination);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0000151(ubiquitin ligase complex);GO:0000151(ubiquitin ligase complex)","04141(Protein processing in endoplasmic reticulum);04120(Ubiquitin mediated proteolysis);04120(Ubiquitin mediated proteolysis)","K06689","EC:2.3.2.23","ubiquitin conjugating enzyme E2 D1 [Source:HGNC Symbol;Acc:HGNC:12474]",{"v":18.5262635616753,"d":"18.53"},{"v":18.8674169297189,"d":"18.87"},{"v":0.981918385048976,"d":"0.98"},{"v":-0.0263249790829792,"d":"-0.03"},{"v":0.651655858104851,"d":"0.65"},{"v":0.952261504625307,"d":"0.95"},"down","no"]
["MSTRG.7183","AC016888.1","ENST00000585285","NA","NA","NA","NA",null,{"v":7.088253,"d":"7.09"},{"v":4.763906,"d":"4.76"},{"v":1.48790782185879,"d":"1.49"},{"v":0.573285152073342,"d":"0.57"},{"v":0.652943626329436,"d":"0.65"},{"v":0.952261504625307,"d":"0.95"},"up","no"]
["ENSG00000048544","MRPS10","ENST00000053468","GO:0030529(intracellular ribonucleoprotein complex);GO:0005840(ribosome);GO:0005739(mitochondrion);GO:0003674(molecular_function);GO:0008150(biological_process);GO:0005743(mitochondrial inner membrane);GO:0070125(mitochondrial translational elongation);GO:0070126(mitochondrial translational termination);GO:0005763(mitochondrial small ribosomal subunit)","03010(Ribosome)","K02946","NA","mitochondrial ribosomal protein S10 [Source:HGNC Symbol;Acc:HGNC:14502]",{"v":2.888361,"d":"2.89"},{"v":1.94596,"d":"1.95"},{"v":1.48428590515735,"d":"1.48"},{"v":0.569769012595158,"d":"0.57"},{"v":0.653420514989334,"d":"0.65"},{"v":0.952261504625307,"d":"0.95"},"up","no"]
["MSTRG.10473","APOBEC3F","ENST00000308521;ENST00000491387;ENST00000476513;ENST00000381565","GO:0003723(RNA binding);GO:0005737(cytoplasm);GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0016787(hydrolase activity);GO:0003824(catalytic activity);GO:0030529(intracellular ribonucleoprotein complex);GO:0002376(immune system process);GO:0045087(innate immune response);GO:0051607(defense response to virus);GO:0016814(hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines);GO:0000932(P-body);GO:0005515(protein binding);GO:0045071(negative regulation of viral genome replication);GO:0080111(DNA demethylation);GO:0009972(cytidine deamination);GO:0010529(negative regulation of transposition);GO:0070383(DNA cytosine deamination);GO:0045869(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate);GO:0004126(cytidine deaminase activity);GO:0002230(positive regulation of defense response to virus by host);GO:0016553(base conversion or substitution editing);GO:0048525(negative regulation of viral process);GO:0030895(apolipoprotein B mRNA editing enzyme complex);GO:0030895(apolipoprotein B mRNA editing enzyme complex)","NA","NA","NA","apolipoprotein B mRNA editing enzyme catalytic subunit 3F [Source:HGNC Symbol;Acc:HGNC:17356]",{"v":1.57711772671191,"d":"1.58"},{"v":1.61742518630475,"d":"1.62"},{"v":0.975079243272495,"d":"0.98"},{"v":-0.0364086255321303,"d":"-0.04"},{"v":0.653983335534793,"d":"0.65"},{"v":0.952261504625307,"d":"0.95"},"down","no"]
["ENSG00000119599","DCAF4","ENST00000358377;ENST00000353777;ENST00000553457;ENST00000509320;ENST00000557203;ENST00000505361;ENST00000510612;ENST00000514191;ENST00000513337;ENST00000508412","GO:0016567(protein ubiquitination);GO:0003723(RNA binding);GO:0005654(nucleoplasm);GO:0043687(post-translational protein modification);GO:0005682(U5 snRNP);GO:0008380(RNA splicing);GO:0071011(precatalytic spliceosome);GO:0071013(catalytic step 2 spliceosome);GO:0080008(Cul4-RING E3 ubiquitin ligase complex);GO:0080008(Cul4-RING E3 ubiquitin ligase complex)","NA","NA","NA","DDB1 and CUL4 associated factor 4 [Source:HGNC Symbol;Acc:HGNC:20229]",{"v":0.759890456728185,"d":"0.76"},{"v":0.778758065221287,"d":"0.78"},{"v":0.975772182227428,"d":"0.98"},{"v":-0.0353837400663322,"d":"-0.04"},{"v":0.655073085884424,"d":"0.66"},{"v":0.952261504625307,"d":"0.95"},"down","no"]
["ENSG00000214022","REPIN1","ENST00000487455;ENST00000466559;ENST00000522266;ENST00000482680;ENST00000397281;ENST00000444957;ENST00000475514;ENST00000495535;ENST00000469309;ENST00000519397;ENST00000486714;ENST00000479668;ENST00000467980;ENST00000489432;ENST00000425389;ENST00000518462;ENST00000473391","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0003723(RNA binding);GO:0046872(metal ion binding);GO:0003677(DNA binding);GO:0006260(DNA replication);GO:0005664(nuclear origin of replication recognition complex);GO:0005664(nuclear origin of replication recognition complex)","NA","NA","NA","replication initiator 1 [Source:HGNC Symbol;Acc:HGNC:17922]",{"v":0.772432331469133,"d":"0.77"},{"v":0.513308872445687,"d":"0.51"},{"v":1.50481001387885,"d":"1.50"},{"v":0.589581354535477,"d":"0.59"},{"v":0.657188287888536,"d":"0.66"},{"v":0.953193406155919,"d":"0.95"},"up","no"]
["MSTRG.4034","FBXL3","ENST00000477982;ENST00000355619;ENST00000417323;ENST00000485797;ENST00000470210","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016567(protein ubiquitination);GO:0005829(cytosol);GO:0016604(nuclear body);GO:0048511(rhythmic process);GO:0005515(protein binding);GO:0031648(protein destabilization);GO:0000209(protein polyubiquitination);GO:0043687(post-translational protein modification);GO:0004842(ubiquitin-protein transferase activity);GO:0000151(ubiquitin ligase complex);GO:0042752(regulation of circadian rhythm);GO:0043153(entrainment of circadian clock by photoperiod);GO:0019005(SCF ubiquitin ligase complex);GO:0031146(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process);GO:0043161(proteasome-mediated ubiquitin-dependent protein catabolic process);GO:0043161(proteasome-mediated ubiquitin-dependent protein catabolic process)","04710(Circadian rhythm);04710(Circadian rhythm)","K10269","NA","F-box and leucine rich repeat protein 3 [Source:HGNC Symbol;Acc:HGNC:13599]",{"v":10.7187907949732,"d":"10.72"},{"v":7.27144042982208,"d":"7.27"},{"v":1.4740945619265,"d":"1.47"},{"v":0.559829075075166,"d":"0.56"},{"v":0.657459673065436,"d":"0.66"},{"v":0.953193406155919,"d":"0.95"},"up","no"]
["MSTRG.10953","MAPKAPK3","ENST00000357955;ENST00000621469;ENST00000497283;ENST00000486712;ENST00000446044;ENST00000430409;ENST00000457064;ENST00000451680","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0005654(nucleoplasm);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0000165(MAPK cascade);GO:0016310(phosphorylation);GO:0005515(protein binding);GO:0005829(cytosol);GO:0007166(cell surface receptor signaling pathway);GO:0032496(response to lipopolysaccharide);GO:0005516(calmodulin binding);GO:0006950(response to stress);GO:0007165(signal transduction);GO:0048010(vascular endothelial growth factor receptor signaling pathway);GO:0018105(peptidyl-serine phosphorylation);GO:0000187(activation of MAPK activity);GO:0034097(response to cytokine);GO:0002224(toll-like receptor signaling pathway);GO:0007265(Ras protein signal transduction);GO:0004708(MAP kinase kinase activity);GO:0004683(calmodulin-dependent protein kinase activity);GO:0009931(calcium-dependent protein serine/threonine kinase activity);GO:0051019(mitogen-activated protein kinase binding);GO:0044351(macropinocytosis);GO:0046777(protein autophosphorylation);GO:0046777(protein autophosphorylation)","04010(MAPK signaling pathway);04370(VEGF signaling pathway);04370(VEGF signaling pathway)","K04444","EC:2.7.11.1","mitogen-activated protein kinase-activated protein kinase 3 [Source:HGNC Symbol;Acc:HGNC:6888]",{"v":13.9894911553175,"d":"13.99"},{"v":14.1724890629941,"d":"14.17"},{"v":0.987087807451238,"d":"0.99"},{"v":-0.0187496680174038,"d":"-0.02"},{"v":0.659878113817387,"d":"0.66"},{"v":0.954186552476628,"d":"0.95"},"down","no"]
["MSTRG.14460","CPQ","ENST00000220763;ENST00000519900;ENST00000525310;ENST00000529551;ENST00000521142;ENST00000519484;ENST00000517742;ENST00000522617;ENST00000532528","GO:0005615(extracellular space);GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0016787(hydrolase activity);GO:0005794(Golgi apparatus);GO:0005783(endoplasmic reticulum);GO:0042803(protein homodimerization activity);GO:0008233(peptidase activity);GO:0006508(proteolysis);GO:0005576(extracellular region);GO:0004180(carboxypeptidase activity);GO:0008237(metallopeptidase activity);GO:0006590(thyroid hormone generation);GO:0042246(tissue regeneration);GO:0005764(lysosome);GO:0070062(extracellular exosome);GO:0043171(peptide catabolic process);GO:0070573(metallodipeptidase activity);GO:0070573(metallodipeptidase activity)","NA","NA","NA","carboxypeptidase Q [Source:HGNC Symbol;Acc:HGNC:16910]",{"v":10.2645641047151,"d":"10.26"},{"v":10.3959923641886,"d":"10.40"},{"v":0.987357795689978,"d":"0.99"},{"v":-0.0183551160531093,"d":"-0.02"},{"v":0.660500595854747,"d":"0.66"},{"v":0.954385146156672,"d":"0.95"},"down","no"]
["MSTRG.4394","PTGER2","ENST00000245457;ENST00000557436","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0007186(G-protein coupled receptor signaling pathway);GO:0004957(prostaglandin E receptor activity);GO:0004930(G-protein coupled receptor activity);GO:0005886(plasma membrane);GO:0004871(signal transducer activity);GO:0007165(signal transduction);GO:0005887(integral component of plasma membrane);GO:0071380(cellular response to prostaglandin E stimulus);GO:0007189(adenylate cyclase-activating G-protein coupled receptor signaling pathway);GO:0032496(response to lipopolysaccharide);GO:0032570(response to progesterone);GO:0042127(regulation of cell proliferation);GO:0042127(regulation of cell proliferation)","04024(cAMP signaling pathway);04080(Neuroactive ligand-receptor interaction);04924(Renin secretion);04750(Inflammatory mediator regulation of TRP channels);05200(Pathways in cancer);05200(Pathways in cancer)","K04259","NA","prostaglandin E receptor 2 [Source:HGNC Symbol;Acc:HGNC:9594]",{"v":9.05129113708047,"d":"9.05"},{"v":6.14712225839062,"d":"6.15"},{"v":1.47244365031552,"d":"1.47"},{"v":0.558212423892135,"d":"0.56"},{"v":0.662271886211133,"d":"0.66"},{"v":0.954713769605704,"d":"0.95"},"up","no"]
["MSTRG.11314","KPNA4","ENST00000334256;ENST00000469804;ENST00000483437","GO:0005634(nucleus);GO:0006810(transport);GO:0005737(cytoplasm);GO:0008565(protein transporter activity);GO:0015031(protein transport);GO:0005515(protein binding);GO:0006606(protein import into nucleus);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0075733(intracellular transport of virus);GO:0043657(host cell);GO:0008139(nuclear localization sequence binding);GO:0019054(modulation by virus of host process);GO:0005643(nuclear pore);GO:0006607(NLS-bearing protein import into nucleus);GO:0042542(response to hydrogen peroxide);GO:0042542(response to hydrogen peroxide)","NA","NA","NA","karyopherin subunit alpha 4 [Source:HGNC Symbol;Acc:HGNC:6397]",{"v":8.42794356283863,"d":"8.43"},{"v":5.74307941123977,"d":"5.74"},{"v":1.46749556454753,"d":"1.47"},{"v":0.553356142848141,"d":"0.55"},{"v":0.664273792515143,"d":"0.66"},{"v":0.955022210896456,"d":"0.96"},"up","no"]
["MSTRG.11171","GP9","ENST00000307395","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0007155(cell adhesion);GO:0005515(protein binding);GO:0005886(plasma membrane);GO:0005887(integral component of plasma membrane);GO:0007596(blood coagulation);GO:0007599(hemostasis);GO:0030168(platelet activation);GO:0007597(blood coagulation, intrinsic pathway)","04512(ECM-receptor interaction);04640(Hematopoietic cell lineage);04611(Platelet activation)","K06263","NA","glycoprotein IX platelet [Source:HGNC Symbol;Acc:HGNC:4444]",{"v":11.689159,"d":"11.69"},{"v":11.826066,"d":"11.83"},{"v":0.988423284632438,"d":"0.99"},{"v":-0.0167990977495322,"d":"-0.02"},{"v":0.665213430713065,"d":"0.67"},{"v":0.955022210896456,"d":"0.96"},"down","no"]
["MSTRG.6865","NBR2","ENST00000460115;ENST00000467245","NA","NA","NA","NA","neighbor of BRCA1 gene 2 (non-protein coding) [Source:HGNC Symbol;Acc:HGNC:20691]",{"v":0.610343324396783,"d":"0.61"},{"v":0.404737713136729,"d":"0.40"},{"v":1.5079971660328,"d":"1.51"},{"v":0.592633717363693,"d":"0.59"},{"v":0.66620467841834,"d":"0.67"},{"v":0.955022210896456,"d":"0.96"},"up","no"]
["MSTRG.6595","TAOK1","ENST00000261716;ENST00000578653;ENST00000577583;ENST00000583121;ENST00000587277","GO:0004672(protein kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0005737(cytoplasm);GO:0000166(nucleotide binding);GO:0004674(protein serine/threonine kinase activity);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0000165(MAPK cascade);GO:0016310(phosphorylation);GO:0006281(DNA repair);GO:0006974(cellular response to DNA damage stimulus);GO:0006915(apoptotic process);GO:0000186(activation of MAPKK activity);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0007399(nervous system development);GO:0007062(sister chromatid cohesion);GO:0042981(regulation of apoptotic process);GO:0005515(protein binding);GO:0007346(regulation of mitotic cell cycle);GO:0032874(positive regulation of stress-activated MAPK cascade);GO:0031572(G2 DNA damage checkpoint);GO:0046330(positive regulation of JNK cascade);GO:0051493(regulation of cytoskeleton organization);GO:0097194(execution phase of apoptosis);GO:0004709(MAP kinase kinase kinase activity);GO:0004709(MAP kinase kinase kinase activity)","04010(MAPK signaling pathway);04010(MAPK signaling pathway)","K04429","EC:2.7.11.1","TAO kinase 1 [Source:HGNC Symbol;Acc:HGNC:29259]",{"v":2.28922654363958,"d":"2.29"},{"v":2.31039482879859,"d":"2.31"},{"v":0.990837806207341,"d":"0.99"},{"v":-0.0132791780720914,"d":"-0.01"},{"v":0.666902945950681,"d":"0.67"},{"v":0.955441104067647,"d":"0.96"},"down","no"]
["MSTRG.6271","MRM3","ENST00000304478;ENST00000571157;ENST00000574916;ENST00000574509","GO:0003723(RNA binding);GO:0006396(RNA processing);GO:0008168(methyltransferase activity);GO:0016740(transferase activity);GO:0032259(methylation);GO:0005739(mitochondrion);GO:0005515(protein binding);GO:0008173(RNA methyltransferase activity);GO:0006364(rRNA processing);GO:0005759(mitochondrial matrix);GO:0070039(rRNA (guanosine-2'-O-)-methyltransferase activity);GO:0000451(rRNA 2'-O-methylation);GO:0001510(RNA methylation);GO:0001510(RNA methylation)","NA","NA","NA","mitochondrial rRNA methyltransferase 3 [Source:HGNC Symbol;Acc:HGNC:18485]",{"v":2.0174502377724,"d":"2.02"},{"v":2.03736993171913,"d":"2.04"},{"v":0.990222838947112,"d":"0.99"},{"v":-0.0141748702330655,"d":"-0.01"},{"v":0.669096277086164,"d":"0.67"},{"v":0.956538260258954,"d":"0.96"},"down","no"]
["ENSG00000142655","PEX14","ENST00000356607;ENST00000472851;ENST00000492696;ENST00000491661","GO:0006810(transport);GO:0005634(nucleus);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0015031(protein transport);GO:0001650(fibrillar center);GO:0005515(protein binding);GO:0005777(peroxisome);GO:0008017(microtubule binding);GO:0005778(peroxisomal membrane);GO:0003714(transcription corepressor activity);GO:0005622(intracellular);GO:0043234(protein complex);GO:0005102(receptor binding);GO:0047485(protein N-terminus binding);GO:0043433(negative regulation of sequence-specific DNA binding transcription factor activity);GO:0045892(negative regulation of transcription, DNA-templated);GO:0007031(peroxisome organization);GO:0016558(protein import into peroxisome matrix);GO:1990429(peroxisomal importomer complex);GO:0032091(negative regulation of protein binding);GO:0048487(beta-tubulin binding);GO:0006461(protein complex assembly);GO:0051260(protein homooligomerization);GO:0034453(microtubule anchoring);GO:0016561(protein import into peroxisome matrix, translocation);GO:0036250(peroxisome transport along microtubule);GO:0044721(protein import into peroxisome matrix, substrate release);GO:1901094(negative regulation of protein homotetramerization);GO:0016560(protein import into peroxisome matrix, docking);GO:0016560(protein import into peroxisome matrix, docking)","04146(Peroxisome);04146(Peroxisome)","K13343","NA","peroxisomal biogenesis factor 14 [Source:HGNC Symbol;Acc:HGNC:8856]",{"v":2.07101465776294,"d":"2.07"},{"v":2.08299113489149,"d":"2.08"},{"v":0.994250346567522,"d":"0.99"},{"v":-0.00831893497414148,"d":"-0.01"},{"v":0.67141736658762,"d":"0.67"},{"v":0.957765615794379,"d":"0.96"},"down","no"]
["ENSG00000075089","ACTR6","ENST00000188312;ENST00000551517;ENST00000547458;ENST00000552376;ENST00000546902;ENST00000548180;ENST00000553038;ENST00000550813","GO:0005634(nucleus);GO:0006338(chromatin remodeling);GO:0005737(cytoplasm);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0005515(protein binding)","NA","NA","NA","ARP6 actin related protein 6 homolog [Source:HGNC Symbol;Acc:HGNC:24025]",{"v":2.64608304274849,"d":"2.65"},{"v":2.66288797167585,"d":"2.66"},{"v":0.993689209194638,"d":"0.99"},{"v":-0.00913339648457437,"d":"-0.01"},{"v":0.672345732959103,"d":"0.67"},{"v":0.958063188300296,"d":"0.96"},"down","no"]
["ENSG00000108599","AKAP10","ENST00000225737;ENST00000395536;ENST00000583951;ENST00000572341;ENST00000474245;ENST00000578898;ENST00000582611;ENST00000576896;ENST00000571858;ENST00000460046","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005829(cytosol);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0005886(plasma membrane);GO:0005739(mitochondrion);GO:0008104(protein localization);GO:0007165(signal transduction);GO:0007596(blood coagulation);GO:0007596(blood coagulation)","NA","NA","NA","A-kinase anchoring protein 10 [Source:HGNC Symbol;Acc:HGNC:368]",{"v":4.56250289232673,"d":"4.56"},{"v":4.59295972442244,"d":"4.59"},{"v":0.993368800528827,"d":"0.99"},{"v":-0.00959865919453916,"d":"-0.01"},{"v":0.673623985854053,"d":"0.67"},{"v":0.958063188300296,"d":"0.96"},"down","no"]
["ENSG00000109881","CCDC34","ENST00000529615;ENST00000328697;ENST00000317945","NA","NA","NA","NA","coiled-coil domain containing 34 [Source:HGNC Symbol;Acc:HGNC:25079]",{"v":0.416394818644522,"d":"0.42"},{"v":0.277743795874632,"d":"0.28"},{"v":1.49920475211073,"d":"1.50"},{"v":0.584197431105818,"d":"0.58"},{"v":0.67445439499382,"d":"0.67"},{"v":0.958231225454266,"d":"0.96"},"up","no"]
["ENSG00000214106","PAXIP1-AS2","ENST00000449486;ENST00000397551;ENST00000411526","NA","NA","NA","NA","PAXIP1 antisense RNA 2 [Source:HGNC Symbol;Acc:HGNC:48958]",{"v":1.88092027874916,"d":"1.88"},{"v":1.28062126462677,"d":"1.28"},{"v":1.46875608792686,"d":"1.47"},{"v":0.554594831595039,"d":"0.55"},{"v":0.676466040601745,"d":"0.68"},{"v":0.958959976746591,"d":"0.96"},"up","no"]
["ENSG00000100802","C14orf93","ENST00000299088;ENST00000397377;ENST00000341470;ENST00000553931;ENST00000553675;ENST00000397382;ENST00000397379;ENST00000553606;ENST00000557513;ENST00000397376;ENST00000555998;ENST00000553958","GO:0003723(RNA binding);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0005576(extracellular region)","NA","NA","NA","chromosome 14 open reading frame 93 [Source:HGNC Symbol;Acc:HGNC:20162]",{"v":1.88648844756069,"d":"1.89"},{"v":1.89843289629979,"d":"1.90"},{"v":0.993708258657769,"d":"0.99"},{"v":-0.00910573964548107,"d":"-0.01"},{"v":0.677347898918525,"d":"0.68"},{"v":0.959016612943883,"d":"0.96"},"down","no"]
["MSTRG.11642","NOA1","ENST00000264230","GO:0003723(RNA binding);GO:0016020(membrane);GO:0005525(GTP binding);GO:0000166(nucleotide binding);GO:0005739(mitochondrion);GO:0005743(mitochondrial inner membrane);GO:0005515(protein binding);GO:0006915(apoptotic process);GO:0032543(mitochondrial translation);GO:0003924(GTPase activity);GO:0031314(extrinsic component of mitochondrial inner membrane);GO:0042254(ribosome biogenesis);GO:0010941(regulation of cell death);GO:0043457(regulation of cellular respiration)","NA","NA","NA","nitric oxide associated 1 [Source:HGNC Symbol;Acc:HGNC:28473]",{"v":4.894471,"d":"4.89"},{"v":4.909921,"d":"4.91"},{"v":0.996853309859772,"d":"1.00"},{"v":-4.54687181659107E-3,"d":"-0.00"},{"v":0.678536415079352,"d":"0.68"},{"v":0.959085125160239,"d":"0.96"},"down","no"]
["ENSG00000111962","UST","ENST00000367463","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016740(transferase activity);GO:0005794(Golgi apparatus);GO:0000139(Golgi membrane);GO:0008146(sulfotransferase activity);GO:0030208(dermatan sulfate biosynthetic process);GO:0006477(protein sulfation);GO:0030010(establishment of cell polarity);GO:0050770(regulation of axonogenesis)","00532(Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate)","K03193","EC:2.8.2.-","uronyl 2-sulfotransferase [Source:HGNC Symbol;Acc:HGNC:17223]",{"v":0.995727327635328,"d":"1.00"},{"v":1.00012680955512,"d":"1.00"},{"v":0.995601075905815,"d":"1.00"},{"v":-0.00636030550539056,"d":"-0.01"},{"v":0.680393716529255,"d":"0.68"},{"v":0.959841135818056,"d":"0.96"},"down","no"]
["ENSG00000163785","RYK","ENST00000623711;ENST00000460933;ENST00000620660;ENST00000480381;ENST00000486725;ENST00000473208;ENST00000481382;ENST00000464879","GO:0004672(protein kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0004713(protein tyrosine kinase activity);GO:0018108(peptidyl-tyrosine phosphorylation);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005109(frizzled binding);GO:0017147(Wnt-protein binding);GO:0042813(Wnt-activated receptor activity);GO:0007409(axonogenesis);GO:0007411(axon guidance);GO:0016055(Wnt signaling pathway);GO:0022038(corpus callosum development);GO:0030182(neuron differentiation);GO:0031175(neuron projection development);GO:0036518(chemorepulsion of dopaminergic neuron axon);GO:0048705(skeletal system morphogenesis);GO:0048843(negative regulation of axon extension involved in axon guidance);GO:0050919(negative chemotaxis);GO:0071679(commissural neuron axon guidance);GO:1904938(planar cell polarity pathway involved in axon guidance);GO:1904948(midbrain dopaminergic neuron differentiation);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005886(plasma membrane);GO:0005886(plasma membrane)","04360(Axon guidance);04360(Axon guidance)","K05128","EC:2.7.10.1","receptor-like tyrosine kinase [Source:HGNC Symbol;Acc:HGNC:10481]",{"v":2.49057211395551,"d":"2.49"},{"v":1.7123277868771,"d":"1.71"},{"v":1.45449494719568,"d":"1.45"},{"v":0.540518284634582,"d":"0.54"},{"v":0.681265726299478,"d":"0.68"},{"v":0.960135739383824,"d":"0.96"},"up","no"]
["ENSG00000185386","MAPK11","ENST00000330651;ENST00000495277","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0016740(transferase activity);GO:0004707(MAP kinase activity);GO:0016301(kinase activity);GO:0000165(MAPK cascade);GO:0016310(phosphorylation);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0005515(protein binding);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0098586(cellular response to virus);GO:0010628(positive regulation of gene expression);GO:0007165(signal transduction);GO:2001184(positive regulation of interleukin-12 secretion);GO:1901796(regulation of signal transduction by p53 class mediator);GO:0048010(vascular endothelial growth factor receptor signaling pathway);GO:0035556(intracellular signal transduction);GO:0006950(response to stress);GO:0000187(activation of MAPK activity);GO:0051149(positive regulation of muscle cell differentiation);GO:0051090(regulation of sequence-specific DNA binding transcription factor activity);GO:0007265(Ras protein signal transduction);GO:0060043(regulation of cardiac muscle cell proliferation);GO:0060044(negative regulation of cardiac muscle cell proliferation);GO:0060044(negative regulation of cardiac muscle cell proliferation)","04015(Rap1 signaling pathway);04010(MAPK signaling pathway);04370(VEGF signaling pathway);04668(TNF signaling pathway);04068(FoxO signaling pathway);04071(Sphingolipid signaling pathway);04218(Cellular senescence);04550(Signaling pathways regulating pluripotency of stem cells);04611(Platelet activation);04620(Toll-like receptor signaling pathway);04621(NOD-like receptor signaling pathway);04622(RIG-I-like receptor signaling pathway);04660(T cell receptor signaling pathway);04658(Th1 and Th2 cell differentiation);04659(Th17 cell differentiation);04657(IL-17 signaling pathway);04664(Fc epsilon RI signaling pathway);04670(Leukocyte transendothelial migration);04912(GnRH signaling pathway);04914(Progesterone-mediated oocyte maturation);04917(Prolactin signaling pathway);04926(Relaxin signaling pathway);04261(Adrenergic signaling in cardiomyocytes);04728(Dopaminergic synapse);04723(Retrograde endocannabinoid signaling);04722(Neurotrophin signaling pathway);04750(Inflammatory mediator regulation of TRP channels);04380(Osteoclast differentiation);05205(Proteoglycans in cancer);05014(Amyotrophic lateral sclerosis (ALS));05418(Fluid shear stress and atherosclerosis);04933(AGE-RAGE signaling pathway in diabetic complications);05120(Epithelial cell signaling in Helicobacter pylori infection);05132(Salmonella infection);05131(Shigellosis);05133(Pertussis);05152(Tuberculosis);05164(Influenza A);05160(Hepatitis C);05167(Kaposi's sarcoma-associated herpesvirus infection);05169(Epstein-Barr virus infection);05145(Toxoplasmosis);05140(Leishmaniasis);05142(Chagas disease (American trypanosomiasis));01522(Endocrine resistance);01522(Endocrine resistance)","K04441","EC:2.7.11.24","mitogen-activated protein kinase 11 [Source:HGNC Symbol;Acc:HGNC:6873]",{"v":0.54325380171131,"d":"0.54"},{"v":0.547488693452381,"d":"0.55"},{"v":0.992264878176083,"d":"0.99"},{"v":-0.0112028055030907,"d":"-0.01"},{"v":0.683446516519674,"d":"0.68"},{"v":0.96087946686961,"d":"0.96"},"down","no"]
["MSTRG.3434","SARNP;DNAJC14;AC023055.1","ENST00000546604;ENST00000336133;ENST00000317269;ENST00000357606;ENST00000552080;ENST00000552946;ENST00000547445;ENST00000552207;ENST00000546957;ENST00000552884;ENST00000317287;MSTRG.3434.2;ENST00000546837","GO:0003723(RNA binding);GO:0006810(transport);GO:0051028(mRNA transport);GO:0005634(nucleus);GO:0016607(nuclear speck);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0000932(P-body);GO:0006406(mRNA export from nucleus);GO:0005654(nucleoplasm);GO:0006417(regulation of translation);GO:0006369(termination of RNA polymerase II transcription);GO:0006405(RNA export from nucleus);GO:0031124(mRNA 3'-end processing);GO:0000346(transcription export complex);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0015031(protein transport);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0070062(extracellular exosome);GO:0000932(P-body)","NA","NA","NA","SAP domain containing ribonucleoprotein [Source:HGNC Symbol;Acc:HGNC:24432];DnaJ heat shock protein family (Hsp40) member C14 [Source:HGNC Symbol;Acc:HGNC:24581]",{"v":4.67869275297981,"d":"4.68"},{"v":4.67338170870834,"d":"4.67"},{"v":1.00113644564097,"d":"1.00"},{"v":1.63861356910619E-3,"d":"0.00"},{"v":0.684042131639248,"d":"0.68"},{"v":0.961367696324166,"d":"0.96"},"up","no"]
["ENSG00000113460","BRIX1","ENST00000336767;ENST00000506023;ENST00000510960;ENST00000510834;ENST00000515798","GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005730(nucleolus);GO:0042254(ribosome biogenesis);GO:0000027(ribosomal large subunit assembly);GO:0000027(ribosomal large subunit assembly)","NA","NA","NA","BRX1, biogenesis of ribosomes [Source:HGNC Symbol;Acc:HGNC:24170]",{"v":1.50710034045101,"d":"1.51"},{"v":1.50310951526641,"d":"1.50"},{"v":1.0026550461853,"d":"1.00"},{"v":0.00382534597392935,"d":"0.00"},{"v":0.68716845350465,"d":"0.69"},{"v":0.963339421073224,"d":"0.96"},"up","no"]
["MSTRG.3393","CSAD","ENST00000498635;ENST00000483632;ENST00000424990;ENST00000491654;ENST00000490923;ENST00000454442;ENST00000379846;ENST00000461392;ENST00000424845;ENST00000379850;ENST00000472908;ENST00000475890;ENST00000379843;ENST00000453446;ENST00000267085;ENST00000444623;ENST00000485004","GO:0003824(catalytic activity);GO:0016829(lyase activity);GO:0016831(carboxy-lyase activity);GO:0030170(pyridoxal phosphate binding);GO:0019752(carboxylic acid metabolic process);GO:0042412(taurine biosynthetic process);GO:0004782(sulfinoalanine decarboxylase activity);GO:0004782(sulfinoalanine decarboxylase activity)","00430(Taurine and hypotaurine metabolism);00430(Taurine and hypotaurine metabolism)","K01594","EC:4.1.1.29","cysteine sulfinic acid decarboxylase [Source:HGNC Symbol;Acc:HGNC:18966]",{"v":1.09692689248292,"d":"1.10"},{"v":1.09438563166287,"d":"1.09"},{"v":1.00232208898447,"d":"1.00"},{"v":0.00334618269724722,"d":"0.00"},{"v":0.68855931798138,"d":"0.69"},{"v":0.963637106805893,"d":"0.96"},"up","no"]
["ENSG00000256667","KLRA1P","ENST00000535939;ENST00000510134","NA","NA","NA","NA","killer cell lectin like receptor A1, pseudogene [Source:HGNC Symbol;Acc:HGNC:6372]",{"v":1.01064642735043,"d":"1.01"},{"v":1.01412835246235,"d":"1.01"},{"v":0.996566583407844,"d":"1.00"},{"v":-4.96189610177782E-3,"d":"-0.00"},{"v":0.6895761083678,"d":"0.69"},{"v":0.963842664910352,"d":"0.96"},"down","no"]
["MSTRG.8990","COA5","ENST00000328709;ENST00000483527;ENST00000466848;ENST00000409997;ENST00000480666","GO:0005515(protein binding);GO:0005739(mitochondrion);GO:0033617(mitochondrial respiratory chain complex IV assembly);GO:0033617(mitochondrial respiratory chain complex IV assembly)","NA","NA","NA","cytochrome c oxidase assembly factor 5 [Source:HGNC Symbol;Acc:HGNC:33848]",{"v":0.822358863043478,"d":"0.82"},{"v":0.825602982608696,"d":"0.83"},{"v":0.996070605807446,"d":"1.00"},{"v":-0.00568008448362303,"d":"-0.01"},{"v":0.69136784736656,"d":"0.69"},{"v":0.964030516083134,"d":"0.96"},"down","no"]
["ENSG00000164654","MIOS","ENST00000340080;ENST00000433056;ENST00000461907;ENST00000445169;ENST00000479694;ENST00000433635;ENST00000405785;ENST00000456533;ENST00000493227","GO:0016020(membrane);GO:0005765(lysosomal membrane);GO:0005764(lysosome);GO:0005515(protein binding);GO:0034198(cellular response to amino acid starvation);GO:0034629(cellular protein complex localization);GO:0032008(positive regulation of TOR signaling);GO:0061700(GATOR2 complex);GO:0061700(GATOR2 complex)","04150(mTOR signaling pathway);04150(mTOR signaling pathway)","K20407","NA","meiosis regulator for oocyte development [Source:HGNC Symbol;Acc:HGNC:21905]",{"v":1.76320268662496,"d":"1.76"},{"v":1.75387347378612,"d":"1.75"},{"v":1.00531920516404,"d":"1.01"},{"v":0.00765365323390059,"d":"0.01"},{"v":0.691761671605422,"d":"0.69"},{"v":0.964030516083134,"d":"0.96"},"up","no"]
["MSTRG.7669","TJP3","ENST00000589378;ENST00000587686;ENST00000587641;ENST00000590545;ENST00000591493;ENST00000587912","GO:0005634(nucleus);GO:0016020(membrane);GO:0005886(plasma membrane);GO:0030054(cell junction);GO:0005923(bicellular tight junction);GO:0005515(protein binding);GO:0005515(protein binding)","04530(Tight junction);04530(Tight junction)","K06097","NA","tight junction protein 3 [Source:HGNC Symbol;Acc:HGNC:11829]",{"v":0.938649633151529,"d":"0.94"},{"v":0.933180805074698,"d":"0.93"},{"v":1.00586041638136,"d":"1.01"},{"v":0.00843011571371222,"d":"0.01"},{"v":0.693547502467393,"d":"0.69"},{"v":0.964030516083134,"d":"0.96"},"up","no"]
["MSTRG.13893","NAMPT","ENST00000486949;ENST00000491027;ENST00000484527;ENST00000354289;ENST00000417537;ENST00000489732;ENST00000222553;MSTRG.13893.1;ENST00000441045;ENST00000489358;ENST00000463871;ENST00000393618;ENST00000467730;ENST00000424768","GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016607(nuclear speck);GO:0016740(transferase activity);GO:0016757(transferase activity, transferring glycosyl groups);GO:0030054(cell junction);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0048511(rhythmic process);GO:0005125(cytokine activity);GO:0005615(extracellular space);GO:0009435(NAD biosynthetic process);GO:0019363(pyridine nucleotide biosynthetic process);GO:0004514(nicotinate-nucleotide diphosphorylase (carboxylating) activity);GO:0008144(drug binding);GO:0042803(protein homodimerization activity);GO:0047280(nicotinamide phosphoribosyltransferase activity);GO:0007565(female pregnancy);GO:0007623(circadian rhythm);GO:0014070(response to organic cyclic compound);GO:0032922(circadian regulation of gene expression);GO:0048661(positive regulation of smooth muscle cell proliferation);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0007165(signal transduction);GO:0007267(cell-cell signaling);GO:0051770(positive regulation of nitric-oxide synthase biosynthetic process);GO:0008284(positive regulation of cell proliferation);GO:0034356(NAD biosynthesis via nicotinamide riboside salvage pathway);GO:0034356(NAD biosynthesis via nicotinamide riboside salvage pathway)","00760(Nicotinate and nicotinamide metabolism);04621(NOD-like receptor signaling pathway);04621(NOD-like receptor signaling pathway)","K03462","EC:2.4.2.12","nicotinamide phosphoribosyltransferase [Source:HGNC Symbol;Acc:HGNC:30092]",{"v":168.318335839586,"d":"168.32"},{"v":116.881446514369,"d":"116.88"},{"v":1.44007745334409,"d":"1.44"},{"v":0.526146407883145,"d":"0.53"},{"v":0.694480488391992,"d":"0.69"},{"v":0.964030516083134,"d":"0.96"},"up","no"]
["ENSG00000106443","PHF14","ENST00000634607;ENST00000498784;ENST00000403050;ENST00000481418;ENST00000490957;ENST00000497851;ENST00000470665;ENST00000473050;ENST00000521747;ENST00000469407;ENST00000489305;ENST00000423760","GO:0046872(metal ion binding);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0008285(negative regulation of cell proliferation);GO:0048286(lung alveolus development);GO:0072201(negative regulation of mesenchymal cell proliferation);GO:2000584(negative regulation of platelet-derived growth factor receptor-alpha signaling pathway);GO:2000791(negative regulation of mesenchymal cell proliferation involved in lung development);GO:0005634(nucleus);GO:0005634(nucleus)","NA","NA","NA","PHD finger protein 14 [Source:HGNC Symbol;Acc:HGNC:22203]",{"v":1.94862788504694,"d":"1.95"},{"v":1.34629572418136,"d":"1.35"},{"v":1.44739959434383,"d":"1.45"},{"v":0.53346327238282,"d":"0.53"},{"v":0.695721634384832,"d":"0.70"},{"v":0.964030516083134,"d":"0.96"},"up","no"]
["ENSG00000176422","SPRYD4","ENST00000338146","GO:0005634(nucleus);GO:0003674(molecular_function);GO:0008150(biological_process);GO:0005739(mitochondrion)","NA","NA","NA","SPRY domain containing 4 [Source:HGNC Symbol;Acc:HGNC:27468]",{"v":0.552005,"d":"0.55"},{"v":0.382525,"d":"0.38"},{"v":1.44305600941115,"d":"1.44"},{"v":0.529127296316674,"d":"0.53"},{"v":0.69616954480666,"d":"0.70"},{"v":0.964030516083134,"d":"0.96"},"up","no"]
["ENSG00000083099","LYRM2","ENST00000523377;ENST00000521961;ENST00000524153;ENST00000520441;ENST00000523075;ENST00000523793;ENST00000517396;ENST00000626778;ENST00000520318;ENST00000412237","GO:0005515(protein binding);GO:0005739(mitochondrion);GO:0005739(mitochondrion)","NA","NA","NA","LYR motif containing 2 [Source:HGNC Symbol;Acc:HGNC:25229]",{"v":1.4103676473096,"d":"1.41"},{"v":0.981138022468026,"d":"0.98"},{"v":1.437481388971,"d":"1.44"},{"v":0.523543277647932,"d":"0.52"},{"v":0.697271382789019,"d":"0.70"},{"v":0.964030516083134,"d":"0.96"},"up","no"]
["MSTRG.10545","POLDIP3","ENST00000348657;ENST00000252115;ENST00000451060;ENST00000491021;ENST00000463133;ENST00000445215;ENST00000339677;ENST00000617178","GO:0005622(intracellular);GO:0003723(RNA binding);GO:0006406(mRNA export from nucleus);GO:0003676(nucleic acid binding);GO:0006810(transport);GO:0051028(mRNA transport);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016607(nuclear speck);GO:0005515(protein binding);GO:0000932(P-body);GO:0045727(positive regulation of translation);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0006417(regulation of translation);GO:0006369(termination of RNA polymerase II transcription);GO:0006405(RNA export from nucleus);GO:0031124(mRNA 3'-end processing);GO:0035145(exon-exon junction complex);GO:0000346(transcription export complex);GO:0016973(poly(A)+ mRNA export from nucleus);GO:0016973(poly(A)+ mRNA export from nucleus)","NA","NA","NA","DNA polymerase delta interacting protein 3 [Source:HGNC Symbol;Acc:HGNC:23782]",{"v":19.4834998961644,"d":"19.48"},{"v":19.2665489758904,"d":"19.27"},{"v":1.01126049717287,"d":"1.01"},{"v":0.0161546783196718,"d":"0.02"},{"v":0.69952670782155,"d":"0.70"},{"v":0.964030516083134,"d":"0.96"},"up","no"]
["ENSG00000119977","TCTN3","ENST00000371217;ENST00000265993;ENST00000614499;ENST00000497399;ENST00000371209;ENST00000478245","GO:0005634(nucleus);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0006915(apoptotic process);GO:0007224(smoothened signaling pathway);GO:0060271(cilium assembly);GO:0070062(extracellular exosome);GO:0030030(cell projection organization);GO:0043065(positive regulation of apoptotic process);GO:0097711(ciliary basal body docking);GO:0060170(ciliary membrane);GO:0060170(ciliary membrane)","NA","NA","NA","tectonic family member 3 [Source:HGNC Symbol;Acc:HGNC:24519]",{"v":3.01095225193919,"d":"3.01"},{"v":2.09279095966491,"d":"2.09"},{"v":1.43872575425368,"d":"1.44"},{"v":0.524791615924693,"d":"0.52"},{"v":0.699826863440512,"d":"0.70"},{"v":0.964030516083134,"d":"0.96"},"up","no"]
["MSTRG.7714","RANBP3","ENST00000591092;ENST00000340578;ENST00000439268;ENST00000034275;ENST00000591333;ENST00000587799;ENST00000593025;ENST00000591124;ENST00000590623;ENST00000592771;ENST00000587463;ENST00000587263;ENST00000591736;ENST00000592266;ENST00000592621;ENST00000589886;ENST00000586117;ENST00000587956;ENST00000587159;ENST00000590953;ENST00000588879;ENST00000587411;ENST00000591881;ENST00000592133;ENST00000592197;ENST00000586344","GO:0006810(transport);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0015031(protein transport);GO:0005654(nucleoplasm);GO:0043547(positive regulation of GTPase activity);GO:0005515(protein binding);GO:0046907(intracellular transport);GO:0005096(GTPase activator activity);GO:0005813(centrosome);GO:0007051(spindle organization);GO:0070412(R-SMAD binding);GO:0006606(protein import into nucleus);GO:0006511(ubiquitin-dependent protein catabolic process);GO:0008536(Ran GTPase binding);GO:0006405(RNA export from nucleus);GO:0000082(G1/S transition of mitotic cell cycle);GO:0046604(positive regulation of mitotic centrosome separation);GO:0046604(positive regulation of mitotic centrosome separation)","05166(HTLV-I infection);05166(HTLV-I infection)","K15304","NA","RAN binding protein 3 [Source:HGNC Symbol;Acc:HGNC:9850]",{"v":4.21021480241773,"d":"4.21"},{"v":2.93214112008059,"d":"2.93"},{"v":1.43588409629548,"d":"1.44"},{"v":0.521939300380848,"d":"0.52"},{"v":0.701077377974762,"d":"0.70"},{"v":0.964082588415177,"d":"0.96"},"up","no"]
["MSTRG.14186","AGPAT5","ENST00000285518;ENST00000533648;ENST00000523586;ENST00000530716","GO:0005634(nucleus);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016740(transferase activity);GO:0016746(transferase activity, transferring acyl groups);GO:0006629(lipid metabolic process);GO:0008152(metabolic process);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005739(mitochondrion);GO:0005515(protein binding);GO:0008654(phospholipid biosynthetic process);GO:0003841(1-acylglycerol-3-phosphate O-acyltransferase activity);GO:0002244(hematopoietic progenitor cell differentiation);GO:0006639(acylglycerol metabolic process);GO:0016024(CDP-diacylglycerol biosynthetic process);GO:0005741(mitochondrial outer membrane);GO:0005635(nuclear envelope);GO:0006654(phosphatidic acid biosynthetic process);GO:0006654(phosphatidic acid biosynthetic process)","00561(Glycerolipid metabolism);00564(Glycerophospholipid metabolism);04072(Phospholipase D signaling pathway);04072(Phospholipase D signaling pathway)","K19007","EC:2.3.1.51","1-acylglycerol-3-phosphate O-acyltransferase 5 [Source:HGNC Symbol;Acc:HGNC:20886]",{"v":0.702121767719898,"d":"0.70"},{"v":0.487451390905209,"d":"0.49"},{"v":1.44039340295253,"d":"1.44"},{"v":0.526462897066918,"d":"0.53"},{"v":0.701629785925477,"d":"0.70"},{"v":0.964377642792349,"d":"0.96"},"up","no"]
["MSTRG.204","CAPZB","ENST00000482808;ENST00000375144;ENST00000375142;MSTRG.204.4;ENST00000264202;ENST00000264203;ENST00000433834;ENST00000457768;ENST00000459967;ENST00000489607","GO:0005737(cytoplasm);GO:0003779(actin binding);GO:0051016(barbed-end actin filament capping);GO:0008290(F-actin capping protein complex);GO:0030036(actin cytoskeleton organization);GO:0051693(actin filament capping);GO:0005856(cytoskeleton);GO:0005829(cytosol);GO:0045296(cadherin binding);GO:0070062(extracellular exosome);GO:0051015(actin filament binding);GO:0007010(cytoskeleton organization);GO:0022604(regulation of cell morphogenesis);GO:0071203(WASH complex);GO:0019886(antigen processing and presentation of exogenous peptide antigen via MHC class II);GO:0006888(ER to Golgi vesicle-mediated transport);GO:0015629(actin cytoskeleton);GO:0006928(movement of cell or subcellular component);GO:0030017(sarcomere);GO:0007596(blood coagulation);GO:0005884(actin filament);GO:0010591(regulation of lamellipodium assembly);GO:0051490(negative regulation of filopodium assembly);GO:0048487(beta-tubulin binding);GO:0030030(cell projection organization);GO:0030032(lamellipodium assembly);GO:0031115(negative regulation of microtubule polymerization);GO:0031175(neuron projection development);GO:0048747(muscle fiber development);GO:0090036(regulation of protein kinase C signaling);GO:0001669(acrosomal vesicle);GO:0005903(brush border);GO:0014704(intercalated disc);GO:0016020(membrane);GO:0030018(Z disc);GO:0030027(lamellipodium);GO:0030863(cortical cytoskeleton);GO:0030863(cortical cytoskeleton)","04144(Endocytosis);04144(Endocytosis)","K10365","NA","capping actin protein of muscle Z-line beta subunit [Source:HGNC Symbol;Acc:HGNC:1491]",{"v":41.7428300030883,"d":"41.74"},{"v":41.1675980416924,"d":"41.17"},{"v":1.01397292989534,"d":"1.01"},{"v":0.0200191371271862,"d":"0.02"},{"v":0.703261447211785,"d":"0.70"},{"v":0.964793288419429,"d":"0.96"},"up","no"]
["MSTRG.8219","RELB","ENST00000505236;ENST00000221452;ENST00000625761;ENST00000509229;ENST00000509480;ENST00000589972;ENST00000510184","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0048511(rhythmic process);GO:0005813(centrosome);GO:0005815(microtubule organizing center);GO:0045087(innate immune response);GO:0003682(chromatin binding);GO:0006954(inflammatory response);GO:0001047(core promoter binding);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0019901(protein kinase binding);GO:0002223(stimulatory C-type lectin receptor signaling pathway);GO:0038061(NIK/NF-kappaB signaling);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0000981(RNA polymerase II transcription factor activity, sequence-specific DNA binding);GO:0043234(protein complex);GO:0000977(RNA polymerase II regulatory region sequence-specific DNA binding);GO:0003714(transcription corepressor activity);GO:0032922(circadian regulation of gene expression);GO:0034097(response to cytokine);GO:0007249(I-kappaB kinase/NF-kappaB signaling);GO:0010628(positive regulation of gene expression);GO:0019882(antigen processing and presentation);GO:0032688(negative regulation of interferon-beta production);GO:0042088(T-helper 1 type immune response);GO:0043011(myeloid dendritic cell differentiation);GO:0045063(T-helper 1 cell differentiation);GO:0045892(negative regulation of transcription, DNA-templated);GO:0071470(cellular response to osmotic stress);GO:0033256(I-kappaB/NF-kappaB complex);GO:0033256(I-kappaB/NF-kappaB complex)","04010(MAPK signaling pathway);04064(NF-kappa B signaling pathway);04380(Osteoclast differentiation);05166(HTLV-I infection);05169(Epstein-Barr virus infection);05169(Epstein-Barr virus infection)","K09253","NA","RELB proto-oncogene, NF-kB subunit [Source:HGNC Symbol;Acc:HGNC:9956]",{"v":7.0414268306425,"d":"7.04"},{"v":4.91875884514003,"d":"4.92"},{"v":1.43154544720154,"d":"1.43"},{"v":0.517573472231434,"d":"0.52"},{"v":0.705857916749867,"d":"0.71"},{"v":0.965721937498707,"d":"0.97"},"up","no"]
["MSTRG.3797","RNF10","MSTRG.3797.4;ENST00000413266;ENST00000325954;ENST00000544805;ENST00000542438;ENST00000543757;ENST00000540046;ENST00000535395;ENST00000366112;ENST00000535470;ENST00000543578;ENST00000536869;ENST00000538796;ENST00000537740;ENST00000538254;ENST00000542207;ENST00000535417;ENST00000542701;ENST00000546262;ENST00000537376;ENST00000543675;ENST00000545419;ENST00000544124","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0045893(positive regulation of transcription, DNA-templated);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0044212(transcription regulatory region DNA binding);GO:0004842(ubiquitin-protein transferase activity);GO:0051865(protein autoubiquitination);GO:0031643(positive regulation of myelination);GO:0010626(negative regulation of Schwann cell proliferation);GO:0010626(negative regulation of Schwann cell proliferation)","NA","NA","NA","ring finger protein 10 [Source:HGNC Symbol;Acc:HGNC:10055]",{"v":44.5498178433429,"d":"44.55"},{"v":31.1531479859584,"d":"31.15"},{"v":1.43002620035133,"d":"1.43"},{"v":0.516041579710425,"d":"0.52"},{"v":0.706213235375903,"d":"0.71"},{"v":0.965721937498707,"d":"0.97"},"up","no"]
["MSTRG.2945","NRGN","MSTRG.2945.3;ENST00000284292;ENST00000412681","GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0005516(calmodulin binding);GO:0005547(phosphatidylinositol-3,4,5-trisphosphate binding);GO:0070300(phosphatidic acid binding);GO:0008306(associative learning);GO:0021537(telencephalon development);GO:1900273(positive regulation of long-term synaptic potentiation);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0012510(trans-Golgi network transport vesicle membrane);GO:0014069(postsynaptic density);GO:0030424(axon);GO:0030425(dendrite);GO:0031966(mitochondrial membrane);GO:0043025(neuronal cell body);GO:0044327(dendritic spine head);GO:0045202(synapse);GO:0007399(nervous system development);GO:0007165(signal transduction);GO:0007165(signal transduction)","NA","NA","NA","neurogranin [Source:HGNC Symbol;Acc:HGNC:8000]",{"v":215.020340564249,"d":"215.02"},{"v":150.537139877863,"d":"150.54"},{"v":1.42835409745863,"d":"1.43"},{"v":0.514353676370079,"d":"0.51"},{"v":0.707941442633261,"d":"0.71"},{"v":0.965721937498707,"d":"0.97"},"up","no"]
["MSTRG.12342","H2AFY","ENST00000512507;ENST00000511494;ENST00000360597;ENST00000505827;MSTRG.12342.3;MSTRG.12342.2;ENST00000511689;ENST00000312469;ENST00000423969;ENST00000451949;ENST00000506671;ENST00000506532;ENST00000506218;ENST00000304332;ENST00000508785;ENST00000508120;ENST00000508962;ENST00000504197;ENST00000513268;ENST00000513210;ENST00000507868","GO:0005634(nucleus);GO:0016569(covalent chromatin modification);GO:0003677(DNA binding);GO:0031490(chromatin DNA binding);GO:0046982(protein heterodimerization activity);GO:0006334(nucleosome assembly);GO:0000786(nucleosome);GO:0000790(nuclear chromatin);GO:0005694(chromosome);GO:0005515(protein binding);GO:0005730(nucleolus);GO:0010385(double-stranded methylated DNA binding);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0070062(extracellular exosome);GO:0019901(protein kinase binding);GO:0035098(ESC/E(Z) complex);GO:0000784(nuclear chromosome, telomeric region);GO:0044212(transcription regulatory region DNA binding);GO:0001046(core promoter sequence-specific DNA binding);GO:0019216(regulation of lipid metabolic process);GO:0000977(RNA polymerase II regulatory region sequence-specific DNA binding);GO:0019899(enzyme binding);GO:0000228(nuclear chromosome);GO:0006342(chromatin silencing);GO:0061086(negative regulation of histone H3-K27 methylation);GO:0000182(rDNA binding);GO:0000979(RNA polymerase II core promoter sequence-specific DNA binding);GO:0003682(chromatin binding);GO:0030291(protein serine/threonine kinase inhibitor activity);GO:0031492(nucleosomal DNA binding);GO:0007549(dosage compensation);GO:0033128(negative regulation of histone phosphorylation);GO:0034184(positive regulation of maintenance of mitotic sister chromatid cohesion);GO:0040029(regulation of gene expression, epigenetic);GO:0045618(positive regulation of keratinocyte differentiation);GO:0045814(negative regulation of gene expression, epigenetic);GO:0045815(positive regulation of gene expression, epigenetic);GO:0051572(negative regulation of histone H3-K4 methylation);GO:0071169(establishment of protein localization to chromatin);GO:0071901(negative regulation of protein serine/threonine kinase activity);GO:1901837(negative regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter);GO:1902750(negative regulation of cell cycle G2/M phase transition);GO:1902882(regulation of response to oxidative stress);GO:1904815(negative regulation of protein localization to chromosome, telomeric region);GO:0000785(chromatin);GO:0000793(condensed chromosome);GO:0001739(sex chromatin);GO:0001740(Barr body);GO:0005721(pericentric heterochromatin);GO:0005721(pericentric heterochromatin)","04217(Necroptosis);05322(Systemic lupus erythematosus);05034(Alcoholism);05034(Alcoholism)","K11251","NA","H2A histone family member Y [Source:HGNC Symbol;Acc:HGNC:4740]",{"v":8.08538481167513,"d":"8.09"},{"v":7.94757546565144,"d":"7.95"},{"v":1.01733979710155,"d":"1.02"},{"v":0.0248016277849052,"d":"0.02"},{"v":0.708271977288813,"d":"0.71"},{"v":0.965721937498707,"d":"0.97"},"up","no"]
["MSTRG.2824","AASDHPPT","ENST00000278618;ENST00000524411;ENST00000525660;ENST00000533423;ENST00000534152","GO:0000287(magnesium ion binding);GO:0006633(fatty acid biosynthetic process);GO:0008897(holo-[acyl-carrier-protein] synthase activity);GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0016740(transferase activity);GO:0005515(protein binding);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0015939(pantothenate metabolic process);GO:0019878(lysine biosynthetic process via aminoadipic acid);GO:0019878(lysine biosynthetic process via aminoadipic acid)","00770(Pantothenate and CoA biosynthesis);00770(Pantothenate and CoA biosynthesis)","K06133","EC:2.7.8.-","aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase [Source:HGNC Symbol;Acc:HGNC:14235]",{"v":2.62430237991266,"d":"2.62"},{"v":2.5732234633673,"d":"2.57"},{"v":1.01985016741551,"d":"1.02"},{"v":0.028357212388202,"d":"0.03"},{"v":0.710764757541432,"d":"0.71"},{"v":0.966277490992669,"d":"0.97"},"up","no"]
["MSTRG.7138","SMARCD2","ENST00000448276;ENST00000323347;ENST00000581832;ENST00000225742;ENST00000577990;ENST00000578234;ENST00000577686;ENST00000580054;ENST00000584483;ENST00000613943","GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0016569(covalent chromatin modification);GO:0000790(nuclear chromatin);GO:0005515(protein binding);GO:0043044(ATP-dependent chromatin remodeling);GO:0016514(SWI/SNF complex);GO:0003713(transcription coactivator activity);GO:0043234(protein complex);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0006337(nucleosome disassembly);GO:0006338(chromatin remodeling);GO:0031492(nucleosomal DNA binding);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:0000980(RNA polymerase II distal enhancer sequence-specific DNA binding);GO:0090544(BAF-type complex);GO:0090544(BAF-type complex)","05225(Hepatocellular carcinoma);05225(Hepatocellular carcinoma)","K11650","NA","SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2 [Source:HGNC Symbol;Acc:HGNC:11107]",{"v":15.1936293725228,"d":"15.19"},{"v":14.9176646076593,"d":"14.92"},{"v":1.01849919354815,"d":"1.02"},{"v":0.026444837972389,"d":"0.03"},{"v":0.711226714344972,"d":"0.71"},{"v":0.966277490992669,"d":"0.97"},"up","no"]
["ENSG00000160219","GAB3","ENST00000369575;ENST00000424127;ENST00000454973;ENST00000369568;ENST00000475685;ENST00000496390","GO:0030225(macrophage differentiation);GO:0030225(macrophage differentiation)","NA","NA","NA","GRB2 associated binding protein 3 [Source:HGNC Symbol;Acc:HGNC:17515]",{"v":3.17542974317147,"d":"3.18"},{"v":2.22346004931715,"d":"2.22"},{"v":1.42814787436666,"d":"1.43"},{"v":0.514145367721555,"d":"0.51"},{"v":0.712754278752017,"d":"0.71"},{"v":0.966277490992669,"d":"0.97"},"up","no"]
["MSTRG.14812","RPSAP9","ENST00000418207","NA","NA","NA","NA","ribosomal protein SA pseudogene 9 [Source:HGNC Symbol;Acc:HGNC:31463]",{"v":0.96663,"d":"0.97"},{"v":0.975929,"d":"0.98"},{"v":0.990471642916647,"d":"0.99"},{"v":-0.0138124233658925,"d":"-0.01"},{"v":0.713627460586227,"d":"0.71"},{"v":0.966277490992669,"d":"0.97"},"down","no"]
["MSTRG.1356","CD55;AL391597.1","ENST00000367067;ENST00000314754;ENST00000367064;ENST00000367063;MSTRG.1356.4;ENST00000465534;ENST00000343420;ENST00000618707;ENST00000635614;ENST00000391921;ENST00000488171;ENST00000476590","GO:0016020(membrane);GO:0005886(plasma membrane);GO:0005576(extracellular region);GO:0031225(anchored component of membrane);GO:0045121(membrane raft);GO:0002376(immune system process);GO:0045087(innate immune response);GO:0030449(regulation of complement activation);GO:0008289(lipid binding);GO:0046718(viral entry into host cell);GO:0005515(protein binding);GO:0070062(extracellular exosome);GO:0016032(viral process);GO:0005887(integral component of plasma membrane);GO:0043312(neutrophil degranulation);GO:2000563(positive regulation of CD4-positive, alpha-beta T cell proliferation);GO:0006958(complement activation, classical pathway);GO:0009986(cell surface);GO:0030667(secretory granule membrane);GO:0006888(ER to Golgi vesicle-mediated transport);GO:0000139(Golgi membrane);GO:0030133(transport vesicle);GO:0007204(positive regulation of cytosolic calcium ion concentration);GO:0033116(endoplasmic reticulum-Golgi intermediate compartment membrane);GO:0001618(virus receptor activity);GO:0101003(ficolin-1-rich granule membrane);GO:0031664(regulation of lipopolysaccharide-mediated signaling pathway);GO:0035743(CD4-positive, alpha-beta T cell cytokine production);GO:0045730(respiratory burst);GO:0045916(negative regulation of complement activation);GO:2000516(positive regulation of CD4-positive, alpha-beta T cell activation);GO:0043086(negative regulation of catalytic activity);GO:0004857(enzyme inhibitor activity);GO:0007283(spermatogenesis);GO:0043434(response to peptide hormone);GO:0060137(maternal process involved in parturition);GO:0016324(apical plasma membrane);GO:0016324(apical plasma membrane)","04640(Hematopoietic cell lineage);04610(Complement and coagulation cascades);05416(Viral myocarditis);05416(Viral myocarditis)","K04006","NA","CD55 molecule (Cromer blood group) [Source:HGNC Symbol;Acc:HGNC:2665]",{"v":26.8187214347525,"d":"26.82"},{"v":26.2709167047421,"d":"26.27"},{"v":1.02085213607759,"d":"1.02"},{"v":0.0297739161706194,"d":"0.03"},{"v":0.714247226133829,"d":"0.71"},{"v":0.966352508502158,"d":"0.97"},"up","no"]
["MSTRG.2695","ATG16L2","ENST00000435507;ENST00000439504;MSTRG.2695.2;ENST00000321297;ENST00000536995;ENST00000544490;ENST00000542481;ENST00000535830;ENST00000537837;ENST00000534905;ENST00000540567;ENST00000541367;ENST00000538842;ENST00000542908;ENST00000538973;ENST00000451353;ENST00000537143;ENST00000541554;ENST00000545248;ENST00000541999","GO:0006810(transport);GO:0005737(cytoplasm);GO:0015031(protein transport);GO:0005654(nucleoplasm);GO:0006914(autophagy);GO:0000045(autophagosome assembly);GO:0000421(autophagosome membrane);GO:0039689(negative stranded viral RNA replication);GO:0039689(negative stranded viral RNA replication)","04140(Autophagy - animal);04140(Autophagy - animal)","K20868","NA","autophagy related 16 like 2 [Source:HGNC Symbol;Acc:HGNC:25464]",{"v":13.8262529714367,"d":"13.83"},{"v":9.72297291921192,"d":"9.72"},{"v":1.42201907650252,"d":"1.42"},{"v":0.507940818959419,"d":"0.51"},{"v":0.71629792536575,"d":"0.72"},{"v":0.966849278069773,"d":"0.97"},"up","no"]
["ENSG00000106723","SPIN1","ENST00000375859;ENST00000483785;ENST00000485804;ENST00000469017;ENST00000485565","GO:0005634(nucleus);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0016569(covalent chromatin modification);GO:0031965(nuclear membrane);GO:0005515(protein binding);GO:0007049(cell cycle);GO:0007276(gamete generation);GO:0005819(spindle);GO:0007275(multicellular organism development);GO:0016055(Wnt signaling pathway);GO:0051321(meiotic cell cycle);GO:0005730(nucleolus);GO:0035064(methylated histone binding);GO:0030177(positive regulation of Wnt signaling pathway);GO:0009303(rRNA transcription);GO:0009303(rRNA transcription)","NA","NA","NA","spindlin 1 [Source:HGNC Symbol;Acc:HGNC:11243]",{"v":4.22758448575499,"d":"4.23"},{"v":2.96650774481074,"d":"2.97"},{"v":1.42510482001951,"d":"1.43"},{"v":0.511068037004235,"d":"0.51"},{"v":0.716597646709023,"d":"0.72"},{"v":0.966849278069773,"d":"0.97"},"up","no"]
["ENSG00000158234","FAIM","ENST00000393034;ENST00000470889;ENST00000393035","GO:0005737(cytoplasm);GO:0043066(negative regulation of apoptotic process);GO:0005515(protein binding);GO:0006915(apoptotic process);GO:0006915(apoptotic process)","NA","NA","NA","Fas apoptotic inhibitory molecule [Source:HGNC Symbol;Acc:HGNC:18703]",{"v":0.386987293958743,"d":"0.39"},{"v":0.386258046905697,"d":"0.39"},{"v":1.00188797892727,"d":"1.00"},{"v":0.00272120984978983,"d":"0.00"},{"v":0.718582980886825,"d":"0.72"},{"v":0.967036087309066,"d":"0.97"},"up","no"]
["ENSG00000151292","CSNK1G3","ENST00000345990;ENST00000361991;ENST00000515322;ENST00000510842;ENST00000514131;ENST00000508708;ENST00000360683;ENST00000521364","GO:0005737(cytoplasm);GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0016055(Wnt signaling pathway);GO:0005634(nucleus);GO:0008360(regulation of cell shape);GO:0007165(signal transduction);GO:0006464(cellular protein modification process);GO:0006897(endocytosis);GO:0018105(peptidyl-serine phosphorylation);GO:0018105(peptidyl-serine phosphorylation)","04340(Hedgehog signaling pathway);04340(Hedgehog signaling pathway)","K08958","EC:2.7.11.1","casein kinase 1 gamma 3 [Source:HGNC Symbol;Acc:HGNC:2456]",{"v":2.2010752882,"d":"2.20"},{"v":2.1612712798,"d":"2.16"},{"v":1.01841694227468,"d":"1.02"},{"v":0.0263283250710259,"d":"0.03"},{"v":0.719450911206246,"d":"0.72"},{"v":0.967609700633093,"d":"0.97"},"up","no"]
["MSTRG.3126","AC010186.3","ENST00000537616","NA","NA","NA","NA",null,{"v":4.128664,"d":"4.13"},{"v":4.02942,"d":"4.03"},{"v":1.02462984747184,"d":"1.02"},{"v":0.0351028232299498,"d":"0.04"},{"v":0.721332326796602,"d":"0.72"},{"v":0.967859590602761,"d":"0.97"},"up","no"]
["MSTRG.971","TDRKH","ENST00000458431;ENST00000368824;ENST00000368823;ENST00000368822;ENST00000525790;ENST00000484421;ENST00000368827;ENST00000486986;ENST00000494725;ENST00000368825;ENST00000463553;ENST00000530202","GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005737(cytoplasm);GO:0005739(mitochondrion);GO:0030154(cell differentiation);GO:0031047(gene silencing by RNA);GO:0007283(spermatogenesis);GO:0034587(piRNA metabolic process);GO:0043046(DNA methylation involved in gamete generation);GO:0009566(fertilization);GO:0007140(male meiotic nuclear division);GO:0071547(piP-body);GO:0071546(pi-body);GO:0071546(pi-body)","NA","NA","NA","tudor and KH domain containing [Source:HGNC Symbol;Acc:HGNC:11713]",{"v":0.966355101139042,"d":"0.97"},{"v":0.944113506873527,"d":"0.94"},{"v":1.02355817823131,"d":"1.02"},{"v":0.0335931063284955,"d":"0.03"},{"v":0.72339386888658,"d":"0.72"},{"v":0.967859590602761,"d":"0.97"},"up","no"]
["ENSG00000261324","AC010168.2","ENST00000562691","NA","NA","NA","NA",null,{"v":0.53269,"d":"0.53"},{"v":0.374659,"d":"0.37"},{"v":1.42179955639662,"d":"1.42"},{"v":0.507718089868949,"d":"0.51"},{"v":0.723672994262122,"d":"0.72"},{"v":0.967859590602761,"d":"0.97"},"up","no"]
["MSTRG.10436","GGA1","ENST00000343632;ENST00000475445;ENST00000413251;ENST00000411501;ENST00000463672;ENST00000481613;ENST00000460957;ENST00000381756;ENST00000447515;ENST00000405147;ENST00000423024;ENST00000491295;ENST00000326597;ENST00000449944;ENST00000489772;ENST00000488672;ENST00000406772;ENST00000325180","GO:0006810(transport);GO:0016020(membrane);GO:0006886(intracellular protein transport);GO:0015031(protein transport);GO:0016192(vesicle-mediated transport);GO:0043231(intracellular membrane-bounded organelle);GO:0005654(nucleoplasm);GO:0005794(Golgi apparatus);GO:0005622(intracellular);GO:0030131(clathrin adaptor complex);GO:0005515(protein binding);GO:0005768(endosome);GO:0003674(molecular_function);GO:0044267(cellular protein metabolic process);GO:0061024(membrane organization);GO:0010008(endosome membrane);GO:0043234(protein complex);GO:0046982(protein heterodimerization activity);GO:0031901(early endosome membrane);GO:0030306(ADP-ribosylation factor binding);GO:0045732(positive regulation of protein catabolic process);GO:1901998(toxin transport);GO:1901998(toxin transport)","04142(Lysosome);04142(Lysosome)","K12404","NA","golgi associated, gamma adaptin ear containing, ARF binding protein 1 [Source:HGNC Symbol;Acc:HGNC:17842]",{"v":2.10797505731668,"d":"2.11"},{"v":1.48673401387555,"d":"1.49"},{"v":1.41785621210193,"d":"1.42"},{"v":0.503711233137575,"d":"0.50"},{"v":0.725279962366061,"d":"0.73"},{"v":0.967859590602761,"d":"0.97"},"up","no"]
["MSTRG.10595","TRABD","ENST00000395829;ENST00000395827;ENST00000472677;ENST00000303434;ENST00000463233;ENST00000380909","NA","NA","NA","NA","TraB domain containing [Source:HGNC Symbol;Acc:HGNC:28805]",{"v":11.57213367745,"d":"11.57"},{"v":11.2687852477006,"d":"11.27"},{"v":1.02691935493325,"d":"1.03"},{"v":0.0383228897319087,"d":"0.04"},{"v":0.725709581083661,"d":"0.73"},{"v":0.967859590602761,"d":"0.97"},"up","no"]
["ENSG00000145725","PPIP5K2","ENST00000509597;ENST00000321521;ENST00000627916;ENST00000502481;ENST00000511022;ENST00000515845;ENST00000510672;ENST00000507310;ENST00000358359;ENST00000511724;ENST00000414217;ENST00000504083;ENST00000508935;ENST00000504275","GO:0005737(cytoplasm);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0005829(cytosol);GO:0016311(dephosphorylation);GO:0003993(acid phosphatase activity);GO:0006020(inositol metabolic process);GO:0043647(inositol phosphate metabolic process);GO:0000827(inositol-1,3,4,5,6-pentakisphosphate kinase activity);GO:0000828(inositol hexakisphosphate kinase activity);GO:0000829(inositol heptakisphosphate kinase activity);GO:0000832(inositol hexakisphosphate 5-kinase activity);GO:0033857(diphosphoinositol-pentakisphosphate kinase activity);GO:0052723(inositol hexakisphosphate 1-kinase activity);GO:0052724(inositol hexakisphosphate 3-kinase activity);GO:0032958(inositol phosphate biosynthetic process);GO:0032958(inositol phosphate biosynthetic process)","04070(Phosphatidylinositol signaling system);04070(Phosphatidylinositol signaling system)","K13024","EC:2.7.4.24","diphosphoinositol pentakisphosphate kinase 2 [Source:HGNC Symbol;Acc:HGNC:29035]",{"v":1.82507521592357,"d":"1.83"},{"v":1.28928652275622,"d":"1.29"},{"v":1.4155699169351,"d":"1.42"},{"v":0.501383007685541,"d":"0.50"},{"v":0.726650066389429,"d":"0.73"},{"v":0.967859590602761,"d":"0.97"},"up","no"]
["ENSG00000198416","ZNF658B","ENST00000615961;ENST00000602828","NA","NA","NA","NA","zinc finger protein 658B (pseudogene) [Source:HGNC Symbol;Acc:HGNC:32033]",{"v":0.481737243264049,"d":"0.48"},{"v":0.335722054657429,"d":"0.34"},{"v":1.43492879476034,"d":"1.43"},{"v":0.520979148054331,"d":"0.52"},{"v":0.72844447974228,"d":"0.73"},{"v":0.967902791346389,"d":"0.97"},"up","no"]
["ENSG00000077585","GPR137B","ENST00000366592;ENST00000366591;ENST00000454895;ENST00000419162","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005765(lysosomal membrane);GO:0005764(lysosome);GO:0005887(integral component of plasma membrane);GO:0005887(integral component of plasma membrane)","NA","NA","NA","G protein-coupled receptor 137B [Source:HGNC Symbol;Acc:HGNC:11862]",{"v":2.58299369250758,"d":"2.58"},{"v":1.81969009701169,"d":"1.82"},{"v":1.41946900560122,"d":"1.42"},{"v":0.505351347862171,"d":"0.51"},{"v":0.729442931176219,"d":"0.73"},{"v":0.967902791346389,"d":"0.97"},"up","no"]
["MSTRG.13831","GIGYF1","ENST00000275732;ENST00000472105;ENST00000464111;ENST00000471340","GO:0005515(protein binding);GO:0008150(biological_process);GO:0043234(protein complex);GO:0048009(insulin-like growth factor receptor signaling pathway);GO:0048009(insulin-like growth factor receptor signaling pathway)","NA","NA","NA","GRB10 interacting GYF protein 1 [Source:HGNC Symbol;Acc:HGNC:9126]",{"v":5.08717384379192,"d":"5.09"},{"v":3.60538065315248,"d":"3.61"},{"v":1.41099493595601,"d":"1.41"},{"v":0.49671281012918,"d":"0.50"},{"v":0.73062191817283,"d":"0.73"},{"v":0.968112164274623,"d":"0.97"},"up","no"]
["ENSG00000137871","ZNF280D","ENST00000560587;ENST00000558320;ENST00000558002;ENST00000559446;ENST00000558067;ENST00000559237;ENST00000559920;ENST00000267807;ENST00000561122;ENST00000560121;ENST00000559000;ENST00000560002;ENST00000559352;ENST00000560298;ENST00000560388","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0003677(DNA binding)","NA","NA","NA","zinc finger protein 280D [Source:HGNC Symbol;Acc:HGNC:25953]",{"v":0.811876213882839,"d":"0.81"},{"v":0.788436466800692,"d":"0.79"},{"v":1.02972940505563,"d":"1.03"},{"v":0.0422652720947483,"d":"0.04"},{"v":0.731137649848834,"d":"0.73"},{"v":0.968112164274623,"d":"0.97"},"up","no"]
["MSTRG.15053","POMT1","ENST00000341012;ENST00000402686;ENST00000467848;ENST00000372228;ENST00000494883;ENST00000462375;ENST00000485278;ENST00000415075;ENST00000423007;ENST00000483472","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0097502(mannosylation);GO:0000030(mannosyltransferase activity);GO:0006493(protein O-linked glycosylation);GO:0046872(metal ion binding);GO:0016740(transferase activity);GO:0016757(transferase activity, transferring glycosyl groups);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0006486(protein glycosylation);GO:0007275(multicellular organism development);GO:0005975(carbohydrate metabolic process);GO:0071712(ER-associated misfolded protein catabolic process);GO:0035269(protein O-linked mannosylation);GO:0004169(dolichyl-phosphate-mannose-protein mannosyltransferase activity);GO:0030198(extracellular matrix organization);GO:1904100(positive regulation of protein O-linked glycosylation);GO:0001669(acrosomal vesicle);GO:0016529(sarcoplasmic reticulum);GO:0016529(sarcoplasmic reticulum)","00515(Mannose type O-glycan biosyntheis);00514(Other types of O-glycan biosynthesis);00514(Other types of O-glycan biosynthesis)","K00728","EC:2.4.1.109","protein O-mannosyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:9202]",{"v":1.27792655711225,"d":"1.28"},{"v":1.24387733212461,"d":"1.24"},{"v":1.02737345886791,"d":"1.03"},{"v":0.0389607087427686,"d":"0.04"},{"v":0.732596377822388,"d":"0.73"},{"v":0.968428199846488,"d":"0.97"},"up","no"]
["ENSG00000164117","FBXO8","ENST00000393674;ENST00000515664","GO:0043547(positive regulation of GTPase activity);GO:0006511(ubiquitin-dependent protein catabolic process);GO:0005086(ARF guanyl-nucleotide exchange factor activity);GO:0032012(regulation of ARF protein signal transduction);GO:0005085(guanyl-nucleotide exchange factor activity);GO:0000151(ubiquitin ligase complex);GO:0000151(ubiquitin ligase complex)","NA","NA","NA","F-box protein 8 [Source:HGNC Symbol;Acc:HGNC:13587]",{"v":2.6748480480427,"d":"2.67"},{"v":2.59037831850534,"d":"2.59"},{"v":1.03260903202205,"d":"1.03"},{"v":0.0462941222284033,"d":"0.05"},{"v":0.734327377892345,"d":"0.73"},{"v":0.969173676118047,"d":"0.97"},"up","no"]
["ENSG00000141425","RPRD1A","ENST00000585953;ENST00000399022;ENST00000588737;ENST00000591994;ENST00000587563;ENST00000357384;ENST00000590898;ENST00000592674;ENST00000585879","GO:0005515(protein binding);GO:0005654(nucleoplasm);GO:0042795(snRNA transcription from RNA polymerase II promoter);GO:0016591(DNA-directed RNA polymerase II, holoenzyme);GO:0070940(dephosphorylation of RNA polymerase II C-terminal domain);GO:0070940(dephosphorylation of RNA polymerase II C-terminal domain)","NA","NA","NA","regulation of nuclear pre-mRNA domain containing 1A [Source:HGNC Symbol;Acc:HGNC:25560]",{"v":1.97244054513149,"d":"1.97"},{"v":1.91062399052357,"d":"1.91"},{"v":1.03235411829566,"d":"1.03"},{"v":0.0459379291692384,"d":"0.05"},{"v":0.736125769802973,"d":"0.74"},{"v":0.969827015271447,"d":"0.97"},"up","no"]
["ENSG00000015676","NUDCD3","ENST00000355451;ENST00000497978;ENST00000464812;ENST00000338427;ENST00000460110;ENST00000475952","GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0060271(cilium assembly);GO:0005868(cytoplasmic dynein complex);GO:0006457(protein folding);GO:0051082(unfolded protein binding);GO:0032502(developmental process);GO:1905793(protein localization to pericentriolar material);GO:1905793(protein localization to pericentriolar material)","NA","NA","NA","NudC domain containing 3 [Source:HGNC Symbol;Acc:HGNC:22208]",{"v":3.16799579659844,"d":"3.17"},{"v":3.06261349648967,"d":"3.06"},{"v":1.03440927176399,"d":"1.03"},{"v":0.048807111687697,"d":"0.05"},{"v":0.737718462674038,"d":"0.74"},{"v":0.97024985914039,"d":"0.97"},"up","no"]
["MSTRG.12709","ACOT13","ENST00000230048;ENST00000476436","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016787(hydrolase activity);GO:0005829(cytosol);GO:0005739(mitochondrion);GO:0005856(cytoskeleton);GO:0005819(spindle);GO:0070062(extracellular exosome);GO:0047617(acyl-CoA hydrolase activity);GO:0006637(acyl-CoA metabolic process);GO:0051289(protein homotetramerization);GO:0051289(protein homotetramerization)","NA","NA","NA","acyl-CoA thioesterase 13 [Source:HGNC Symbol;Acc:HGNC:20999]",{"v":0.474970091943559,"d":"0.47"},{"v":0.461675848884843,"d":"0.46"},{"v":1.02879562162679,"d":"1.03"},{"v":0.0409564079352287,"d":"0.04"},{"v":0.738985789487577,"d":"0.74"},{"v":0.97035752751235,"d":"0.97"},"up","no"]
["ENSG00000178234","GALNT11","ENST00000430044;ENST00000415421;ENST00000447778;ENST00000431940;ENST00000431668;ENST00000447796;ENST00000491061;ENST00000422997;ENST00000446096;ENST00000434507;ENST00000482812","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0046872(metal ion binding);GO:0016740(transferase activity);GO:0030246(carbohydrate binding);GO:0016757(transferase activity, transferring glycosyl groups);GO:0005794(Golgi apparatus);GO:0000139(Golgi membrane);GO:0006486(protein glycosylation);GO:0007219(Notch signaling pathway);GO:0060271(cilium assembly);GO:0005112(Notch binding);GO:0016266(O-glycan processing);GO:0007368(determination of left/right symmetry);GO:0008593(regulation of Notch signaling pathway);GO:0007220(Notch receptor processing);GO:0004653(polypeptide N-acetylgalactosaminyltransferase activity);GO:0018243(protein O-linked glycosylation via threonine);GO:0061314(Notch signaling involved in heart development);GO:0061314(Notch signaling involved in heart development)","00512(Mucin type O-glycan biosynthesis);00512(Mucin type O-glycan biosynthesis)","K00710","EC:2.4.1.41","polypeptide N-acetylgalactosaminyltransferase 11 [Source:HGNC Symbol;Acc:HGNC:19875]",{"v":2.01359911416516,"d":"2.01"},{"v":1.94445575611814,"d":"1.94"},{"v":1.03555923441789,"d":"1.04"},{"v":0.050410078673634,"d":"0.05"},{"v":0.740082113774299,"d":"0.74"},{"v":0.970444099270657,"d":"0.97"},"up","no"]
["ENSG00000164331","ANKRA2","ENST00000515804;ENST00000296785;ENST00000515249;ENST00000509433;ENST00000506130;ENST00000505301;ENST00000514916","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005829(cytosol);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0042826(histone deacetylase binding);GO:0005634(nucleus);GO:0008150(biological_process);GO:0019901(protein kinase binding);GO:0043254(regulation of protein complex assembly);GO:0043234(protein complex);GO:0031625(ubiquitin protein ligase binding);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0003712(transcription cofactor activity);GO:1990393(3M complex);GO:0050750(low-density lipoprotein particle receptor binding);GO:0050750(low-density lipoprotein particle receptor binding)","NA","NA","NA","ankyrin repeat family A member 2 [Source:HGNC Symbol;Acc:HGNC:13208]",{"v":3.60811383264385,"d":"3.61"},{"v":3.48316822226401,"d":"3.48"},{"v":1.03587125352752,"d":"1.04"},{"v":0.0508447043375444,"d":"0.05"},{"v":0.740438297688362,"d":"0.74"},{"v":0.970444099270657,"d":"0.97"},"up","no"]
["ENSG00000035720","STAP1","ENST00000265404;ENST00000396225","GO:0010628(positive regulation of gene expression);GO:0071222(cellular response to lipopolysaccharide);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0043231(intracellular membrane-bounded organelle);GO:0005654(nucleoplasm);GO:0009967(positive regulation of signal transduction);GO:0005739(mitochondrion);GO:0005515(protein binding);GO:0005068(transmembrane receptor protein tyrosine kinase adaptor activity);GO:0005070(SH3/SH2 adaptor activity);GO:0005157(macrophage colony-stimulating factor receptor binding);GO:0030971(receptor tyrosine kinase binding);GO:0007169(transmembrane receptor protein tyrosine kinase signaling pathway);GO:0010760(negative regulation of macrophage chemotaxis);GO:0042326(negative regulation of phosphorylation);GO:0060100(positive regulation of phagocytosis, engulfment);GO:1900028(negative regulation of ruffle assembly);GO:1902227(negative regulation of macrophage colony-stimulating factor signaling pathway);GO:1903980(positive regulation of microglial cell activation);GO:1904140(negative regulation of microglial cell migration);GO:1904151(positive regulation of microglial cell mediated cytotoxicity);GO:2000251(positive regulation of actin cytoskeleton reorganization);GO:0043234(protein complex);GO:0019901(protein kinase binding);GO:0005543(phospholipid binding);GO:0001784(phosphotyrosine residue binding);GO:0050861(positive regulation of B cell receptor signaling pathway);GO:1903997(positive regulation of non-membrane spanning protein tyrosine kinase activity);GO:1903997(positive regulation of non-membrane spanning protein tyrosine kinase activity)","NA","NA","NA","signal transducing adaptor family member 1 [Source:HGNC Symbol;Acc:HGNC:24133]",{"v":2.07689592084592,"d":"2.08"},{"v":2.01899180906344,"d":"2.02"},{"v":1.02867971604567,"d":"1.03"},{"v":0.0407938626991263,"d":"0.04"},{"v":0.742705964713738,"d":"0.74"},{"v":0.970444099270657,"d":"0.97"},"up","no"]
["ENSG00000168803","ADAL","ENST00000566154;ENST00000428046;ENST00000565555;ENST00000562188;ENST00000563551;ENST00000389651;ENST00000610420;ENST00000422466","GO:0046872(metal ion binding);GO:0016787(hydrolase activity);GO:0019239(deaminase activity);GO:0009117(nucleotide metabolic process);GO:0005829(cytosol);GO:0043101(purine-containing compound salvage);GO:0004000(adenosine deaminase activity);GO:0017144(drug metabolic process);GO:0006154(adenosine catabolic process);GO:0046103(inosine biosynthetic process);GO:0046103(inosine biosynthetic process)","NA","NA","NA","adenosine deaminase like [Source:HGNC Symbol;Acc:HGNC:31853]",{"v":0.29501892864638,"d":"0.30"},{"v":0.2869371189227,"d":"0.29"},{"v":1.02816578682473,"d":"1.03"},{"v":0.0400729109768771,"d":"0.04"},{"v":0.743962359637947,"d":"0.74"},{"v":0.970444099270657,"d":"0.97"},"up","no"]
["ENSG00000059758","CDK17","ENST00000543119;ENST00000261211;ENST00000552262;ENST00000552496;ENST00000548422;ENST00000549899;ENST00000551816;ENST00000550971;ENST00000551484","GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005737(cytoplasm)","NA","NA","NA","cyclin dependent kinase 17 [Source:HGNC Symbol;Acc:HGNC:8750]",{"v":4.27808556972659,"d":"4.28"},{"v":3.06259506292959,"d":"3.06"},{"v":1.39688253974859,"d":"1.40"},{"v":0.482210713341002,"d":"0.48"},{"v":0.744856718157265,"d":"0.74"},{"v":0.970444099270657,"d":"0.97"},"up","no"]
["ENSG00000230869","AGAP10P","ENST00000454844","NA","NA","NA","NA","ArfGAP with GTPase domain, ankyrin repeat and PH domain 10 pseudogene [Source:HGNC Symbol;Acc:HGNC:23659]",{"v":0.957008,"d":"0.96"},{"v":0.675236,"d":"0.68"},{"v":1.4172941016178,"d":"1.42"},{"v":0.503139161868849,"d":"0.50"},{"v":0.745858399120545,"d":"0.75"},{"v":0.970444099270657,"d":"0.97"},"up","no"]
["ENSG00000240225","ZNF542P","ENST00000495307;ENST00000587208;ENST00000468396;ENST00000595222;ENST00000490123;ENST00000488113;ENST00000467807;ENST00000589844;ENST00000587341","NA","NA","NA","NA","zinc finger protein 542, pseudogene [Source:HGNC Symbol;Acc:HGNC:25393]",{"v":1.86744638763326,"d":"1.87"},{"v":1.32864502430704,"d":"1.33"},{"v":1.40552694923705,"d":"1.41"},{"v":0.491111115872587,"d":"0.49"},{"v":0.746301167779382,"d":"0.75"},{"v":0.970444099270657,"d":"0.97"},"up","no"]
["MSTRG.9107","FAM168B","ENST00000389915;ENST00000409185;MSTRG.9107.1","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005886(plasma membrane);GO:0042995(cell projection);GO:0048471(perinuclear region of cytoplasm);GO:0030424(axon);GO:0070062(extracellular exosome);GO:0070062(extracellular exosome)","NA","NA","NA","family with sequence similarity 168 member B [Source:HGNC Symbol;Acc:HGNC:27016]",{"v":2.9483928890281,"d":"2.95"},{"v":2.10872522713442,"d":"2.11"},{"v":1.39818732715344,"d":"1.40"},{"v":0.483557663896629,"d":"0.48"},{"v":0.747333522819451,"d":"0.75"},{"v":0.970444099270657,"d":"0.97"},"up","no"]
["ENSG00000088543","C3orf18","ENST00000426034;ENST00000357203;ENST00000430746;ENST00000491269;ENST00000486175;ENST00000422619;ENST00000484982","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016021(integral component of membrane)","NA","NA","NA","chromosome 3 open reading frame 18 [Source:HGNC Symbol;Acc:HGNC:24837]",{"v":1.20183821890394,"d":"1.20"},{"v":1.1529276976601,"d":"1.15"},{"v":1.04242288683246,"d":"1.04"},{"v":0.0599406643421842,"d":"0.06"},{"v":0.749302723767546,"d":"0.75"},{"v":0.970545814869179,"d":"0.97"},"up","no"]
["ENSG00000148634","HERC4","ENST00000492996;ENST00000395198;ENST00000373700;ENST00000395185;ENST00000473533;ENST00000505760;ENST00000460168;ENST00000412272;ENST00000277817;ENST00000515753;ENST00000506515;ENST00000463478;ENST00000427635;ENST00000480158","GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0016740(transferase activity);GO:0016567(protein ubiquitination);GO:0001650(fibrillar center);GO:0004842(ubiquitin-protein transferase activity);GO:0030154(cell differentiation);GO:0007283(spermatogenesis);GO:0061630(ubiquitin protein ligase activity);GO:0061630(ubiquitin protein ligase activity)","04120(Ubiquitin mediated proteolysis);04120(Ubiquitin mediated proteolysis)","K10615","EC:2.3.2.26","HECT and RLD domain containing E3 ubiquitin protein ligase 4 [Source:HGNC Symbol;Acc:HGNC:24521]",{"v":2.52548387631728,"d":"2.53"},{"v":1.81200828396542,"d":"1.81"},{"v":1.39374852679508,"d":"1.39"},{"v":0.478970280091913,"d":"0.48"},{"v":0.749955108279606,"d":"0.75"},{"v":0.970766320667468,"d":"0.97"},"up","no"]
["ENSG00000163617","CCDC191","ENST00000295878;ENST00000481358;ENST00000460813;ENST00000527855","NA","NA","NA","NA","coiled-coil domain containing 191 [Source:HGNC Symbol;Acc:HGNC:29272]",{"v":0.742589843673392,"d":"0.74"},{"v":0.716785242127098,"d":"0.72"},{"v":1.03600046433673,"d":"1.04"},{"v":0.0510246496423757,"d":"0.05"},{"v":0.750888725888029,"d":"0.75"},{"v":0.971189208179359,"d":"0.97"},"up","no"]
["MSTRG.4049","IPO5","ENST00000490680;ENST00000491555;ENST00000357602;ENST00000469360;ENST00000470493;ENST00000460070;ENST00000403772;ENST00000493122;ENST00000490369;ENST00000473582;ENST00000468620;ENST00000261574;ENST00000480641","GO:0005622(intracellular);GO:0006886(intracellular protein transport);GO:0008536(Ran GTPase binding);GO:0003723(RNA binding);GO:0006810(transport);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0015031(protein transport);GO:0005515(protein binding);GO:0005730(nucleolus);GO:0071230(cellular response to amino acid stimulus);GO:0016032(viral process);GO:0042307(positive regulation of protein import into nucleus);GO:0008139(nuclear localization sequence binding);GO:0008565(protein transporter activity);GO:0006607(NLS-bearing protein import into nucleus);GO:0005095(GTPase inhibitor activity);GO:0000060(protein import into nucleus, translocation);GO:0006610(ribosomal protein import into nucleus);GO:0034260(negative regulation of GTPase activity);GO:0005643(nuclear pore);GO:0031965(nuclear membrane);GO:0034399(nuclear periphery);GO:0034399(nuclear periphery)","NA","NA","NA","importin 5 [Source:HGNC Symbol;Acc:HGNC:6402]",{"v":4.51486010257471,"d":"4.51"},{"v":4.3240104191914,"d":"4.32"},{"v":1.04413719322605,"d":"1.04"},{"v":0.0623112856463378,"d":"0.06"},{"v":0.752232374692661,"d":"0.75"},{"v":0.971283992886715,"d":"0.97"},"up","no"]
["MSTRG.2063","AC136475.2;IFITM2","MSTRG.2063.2;MSTRG.2063.1;ENST00000526612","NA","NA","NA","NA",null,{"v":21.9204153753501,"d":"21.92"},{"v":15.7793221120448,"d":"15.78"},{"v":1.38918612724292,"d":"1.39"},{"v":0.474239908794221,"d":"0.47"},{"v":0.754857162939692,"d":"0.75"},{"v":0.971852762406419,"d":"0.97"},"up","no"]
["MSTRG.11580","LIAS","ENST00000640381;ENST00000340169;ENST00000513731;ENST00000424936;ENST00000639614;ENST00000509519;ENST00000640816;ENST00000638837;ENST00000381846;ENST00000639422;ENST00000638451;ENST00000640888;ENST00000640689","GO:0046872(metal ion binding);GO:0016740(transferase activity);GO:0003824(catalytic activity);GO:0005739(mitochondrion);GO:0051536(iron-sulfur cluster binding);GO:0051539(4 iron, 4 sulfur cluster binding);GO:0016783(sulfurtransferase activity);GO:0016992(lipoate synthase activity);GO:0001843(neural tube closure);GO:0006954(inflammatory response);GO:0006979(response to oxidative stress);GO:0009107(lipoate biosynthetic process);GO:0009249(protein lipoylation);GO:0032496(response to lipopolysaccharide);GO:0005759(mitochondrial matrix);GO:0034641(cellular nitrogen compound metabolic process);GO:0034641(cellular nitrogen compound metabolic process)","00785(Lipoic acid metabolism);00785(Lipoic acid metabolism)","K03644","EC:2.8.1.8","lipoic acid synthetase [Source:HGNC Symbol;Acc:HGNC:16429]",{"v":0.30740096190882,"d":"0.31"},{"v":0.294276694674052,"d":"0.29"},{"v":1.04459839148766,"d":"1.04"},{"v":0.0629483873078141,"d":"0.06"},{"v":0.755029637485229,"d":"0.76"},{"v":0.971852762406419,"d":"0.97"},"up","no"]
["MSTRG.13510","SNX13","ENST00000611725;ENST00000428135;ENST00000496855;ENST00000409604;ENST00000409076;ENST00000475800;ENST00000492626;ENST00000474067","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0015031(protein transport);GO:0035091(phosphatidylinositol binding);GO:0006886(intracellular protein transport);GO:0043547(positive regulation of GTPase activity);GO:0008289(lipid binding);GO:0005768(endosome);GO:0032266(phosphatidylinositol-3-phosphate binding);GO:0005769(early endosome);GO:0031901(early endosome membrane);GO:0009968(negative regulation of signal transduction);GO:0009968(negative regulation of signal transduction)","NA","NA","NA","sorting nexin 13 [Source:HGNC Symbol;Acc:HGNC:21335]",{"v":2.08460783152637,"d":"2.08"},{"v":1.50073969405531,"d":"1.50"},{"v":1.38905357123815,"d":"1.39"},{"v":0.474102240405868,"d":"0.47"},{"v":0.756657742698536,"d":"0.76"},{"v":0.972020615703329,"d":"0.97"},"up","no"]
["MSTRG.66","GNB1","MSTRG.66.4;ENST00000610897;MSTRG.66.3;ENST00000378609;ENST00000471354;ENST00000434686;ENST00000607589;ENST00000439272;MSTRG.66.7;ENST00000437146;ENST00000472614;ENST00000461893;ENST00000615252;MSTRG.66.6","GO:0007165(signal transduction);GO:0005765(lysosomal membrane);GO:0005515(protein binding);GO:0004871(signal transducer activity);GO:0005886(plasma membrane);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0006457(protein folding);GO:0003924(GTPase activity);GO:0030168(platelet activation);GO:0032403(protein complex binding);GO:1903561(extracellular vesicle);GO:0005834(heterotrimeric G-protein complex);GO:0007265(Ras protein signal transduction);GO:0005622(intracellular);GO:0071377(cellular response to glucagon stimulus);GO:0071380(cellular response to prostaglandin E stimulus);GO:0071870(cellular response to catecholamine stimulus);GO:0016020(membrane);GO:0007223(Wnt signaling pathway, calcium modulating pathway);GO:0051020(GTPase binding);GO:0097381(photoreceptor disc membrane);GO:0016056(rhodopsin mediated signaling pathway);GO:0007213(G-protein coupled acetylcholine receptor signaling pathway);GO:0007191(adenylate cyclase-activating dopamine receptor signaling pathway);GO:0001664(G-protein coupled receptor binding);GO:0030507(spectrin binding);GO:0031702(type 1 angiotensin receptor binding);GO:0047391(alkylglycerophosphoethanolamine phosphodiesterase activity);GO:0007186(G-protein coupled receptor signaling pathway);GO:0007200(phospholipase C-activating G-protein coupled receptor signaling pathway);GO:0007204(positive regulation of cytosolic calcium ion concentration);GO:0008283(cell proliferation);GO:0010659(cardiac muscle cell apoptotic process);GO:0050909(sensory perception of taste);GO:0060041(retina development in camera-type eye);GO:0070208(protein heterotrimerization);GO:0071456(cellular response to hypoxia);GO:0001750(photoreceptor outer segment);GO:0001917(photoreceptor inner segment);GO:0030425(dendrite);GO:0042622(photoreceptor outer segment membrane);GO:0043209(myelin sheath);GO:0044297(cell body);GO:0044297(cell body)","04014(Ras signaling pathway);04371(Apelin signaling pathway);04151(PI3K-Akt signaling pathway);04062(Chemokine signaling pathway);04926(Relaxin signaling pathway);04724(Glutamatergic synapse);04727(GABAergic synapse);04725(Cholinergic synapse);04728(Dopaminergic synapse);04726(Serotonergic synapse);04723(Retrograde endocannabinoid signaling);04744(Phototransduction);04740(Olfactory transduction);04713(Circadian entrainment);05200(Pathways in cancer);05032(Morphine addiction);05034(Alcoholism);05167(Kaposi's sarcoma-associated herpesvirus infection);05167(Kaposi's sarcoma-associated herpesvirus infection)","K04536","NA","G protein subunit beta 1 [Source:HGNC Symbol;Acc:HGNC:4396]",{"v":41.5515967453184,"d":"41.55"},{"v":29.9698145279458,"d":"29.97"},{"v":1.38644824466875,"d":"1.39"},{"v":0.471393762390114,"d":"0.47"},{"v":0.757432125425281,"d":"0.76"},{"v":0.972319380410491,"d":"0.97"},"up","no"]
["ENSG00000085511","MAP3K4","ENST00000366920;ENST00000348824;ENST00000544041;ENST00000392142;ENST00000366919;ENST00000536852;ENST00000542851;ENST00000539610;ENST00000543421;ENST00000541901;ENST00000544733;ENST00000448119;ENST00000490904;ENST00000446500;ENST00000540205","GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0000165(MAPK cascade);GO:0016310(phosphorylation);GO:0005515(protein binding);GO:0048471(perinuclear region of cytoplasm);GO:0004709(MAP kinase kinase kinase activity);GO:0042981(regulation of apoptotic process);GO:0007346(regulation of mitotic cell cycle);GO:0035556(intracellular signal transduction);GO:0032212(positive regulation of telomere maintenance via telomerase);GO:0051973(positive regulation of telomerase activity);GO:1904355(positive regulation of telomere capping);GO:0000186(activation of MAPKK activity);GO:0043507(positive regulation of JUN kinase activity);GO:1900745(positive regulation of p38MAPK cascade);GO:0010225(response to UV-C);GO:0001890(placenta development);GO:0010468(regulation of gene expression);GO:0019100(male germ-line sex determination);GO:0060718(chorionic trophoblast cell differentiation);GO:0060718(chorionic trophoblast cell differentiation)","04010(MAPK signaling pathway);04912(GnRH signaling pathway);04912(GnRH signaling pathway)","K04428","EC:2.7.11.25","mitogen-activated protein kinase kinase kinase 4 [Source:HGNC Symbol;Acc:HGNC:6856]",{"v":3.46689815660729,"d":"3.47"},{"v":2.50081113254454,"d":"2.50"},{"v":1.38630947035163,"d":"1.39"},{"v":0.471249350912554,"d":"0.47"},{"v":0.75873230218547,"d":"0.76"},{"v":0.972319380410491,"d":"0.97"},"up","no"]
["ENSG00000113240","CLK4","ENST00000520878;ENST00000519583;ENST00000316308;ENST00000522136;ENST00000523013;ENST00000520957;ENST00000520199;ENST00000611575;ENST00000519132;ENST00000520126;ENST00000522749;ENST00000521621","GO:0005634(nucleus);GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0004713(protein tyrosine kinase activity);GO:0005515(protein binding);GO:0043484(regulation of RNA splicing);GO:0004712(protein serine/threonine/tyrosine kinase activity);GO:0018108(peptidyl-tyrosine phosphorylation);GO:0046777(protein autophosphorylation);GO:0046777(protein autophosphorylation)","NA","NA","NA","CDC like kinase 4 [Source:HGNC Symbol;Acc:HGNC:13659]",{"v":3.04471734023221,"d":"3.04"},{"v":2.90098359805654,"d":"2.90"},{"v":1.04954655457961,"d":"1.05"},{"v":0.069766161457626,"d":"0.07"},{"v":0.760658996706453,"d":"0.76"},{"v":0.972641811137639,"d":"0.97"},"up","no"]
["ENSG00000154608","CEP170P1","ENST00000502249","NA","NA","NA","NA","centrosomal protein 170 pseudogene 1 [Source:HGNC Symbol;Acc:HGNC:28364]",{"v":0.394276,"d":"0.39"},{"v":0.279617,"d":"0.28"},{"v":1.41005732841708,"d":"1.41"},{"v":0.495753819178465,"d":"0.50"},{"v":0.761625125317459,"d":"0.76"},{"v":0.973125330051548,"d":"0.97"},"up","no"]
["MSTRG.15101","AGPAT2","ENST00000371696;ENST00000470861;ENST00000371694;ENST00000472820","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016740(transferase activity);GO:0016746(transferase activity, transferring acyl groups);GO:0006629(lipid metabolic process);GO:0008152(metabolic process);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0008654(phospholipid biosynthetic process);GO:0003841(1-acylglycerol-3-phosphate O-acyltransferase activity);GO:0016024(CDP-diacylglycerol biosynthetic process);GO:0005886(plasma membrane);GO:0043312(neutrophil degranulation);GO:0035579(specific granule membrane);GO:0006654(phosphatidic acid biosynthetic process);GO:0001819(positive regulation of cytokine production);GO:0001961(positive regulation of cytokine-mediated signaling pathway);GO:0006644(phospholipid metabolic process);GO:0008544(epidermis development);GO:0042493(response to drug);GO:0042493(response to drug)","00561(Glycerolipid metabolism);00564(Glycerophospholipid metabolism);04072(Phospholipase D signaling pathway);04975(Fat digestion and absorption);04975(Fat digestion and absorption)","K13509","EC:2.3.1.51","1-acylglycerol-3-phosphate O-acyltransferase 2 [Source:HGNC Symbol;Acc:HGNC:325]",{"v":7.12185856006674,"d":"7.12"},{"v":6.78652089265851,"d":"6.79"},{"v":1.04941230900372,"d":"1.05"},{"v":0.0695816171769075,"d":"0.07"},{"v":0.764147976888677,"d":"0.76"},{"v":0.974133027758152,"d":"0.97"},"up","no"]
["ENSG00000109501","WFS1","ENST00000513395;ENST00000226760;ENST00000506588;ENST00000507765;ENST00000503569","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005515(protein binding);GO:0055074(calcium ion homeostasis);GO:0030433(ubiquitin-dependent ERAD pathway);GO:0044267(cellular protein metabolic process);GO:0043687(post-translational protein modification);GO:0005788(endoplasmic reticulum lumen);GO:0050821(protein stabilization);GO:0051117(ATPase binding);GO:0036498(IRE1-mediated unfolded protein response);GO:0034976(response to endoplasmic reticulum stress);GO:0031625(ubiquitin protein ligase binding);GO:0051247(positive regulation of protein metabolic process);GO:0007605(sensory perception of sound);GO:0001822(kidney development);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0043524(negative regulation of neuron apoptotic process);GO:0030425(dendrite);GO:0003091(renal water homeostasis);GO:0006983(ER overload response);GO:0007601(visual perception);GO:0022417(protein maturation by protein folding);GO:0031398(positive regulation of protein ubiquitination);GO:0032469(endoplasmic reticulum calcium ion homeostasis);GO:0042593(glucose homeostasis);GO:0043069(negative regulation of programmed cell death);GO:0043433(negative regulation of sequence-specific DNA binding transcription factor activity);GO:0045927(positive regulation of growth);GO:0050877(neurological system process);GO:0051928(positive regulation of calcium ion transport);GO:1903892(negative regulation of ATF6-mediated unfolded protein response);GO:2000675(negative regulation of type B pancreatic cell apoptotic process);GO:0030176(integral component of endoplasmic reticulum membrane);GO:0005516(calmodulin binding);GO:0033613(activating transcription factor binding);GO:0048306(calcium-dependent protein binding);GO:0030968(endoplasmic reticulum unfolded protein response);GO:0031016(pancreas development);GO:0042048(olfactory behavior);GO:0045762(positive regulation of adenylate cyclase activity);GO:1902236(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway);GO:0000502(proteasome complex);GO:0000502(proteasome complex)","04141(Protein processing in endoplasmic reticulum);04141(Protein processing in endoplasmic reticulum)","K14020","NA","wolframin ER transmembrane glycoprotein [Source:HGNC Symbol;Acc:HGNC:12762]",{"v":0.328008867715489,"d":"0.33"},{"v":0.234521170396632,"d":"0.23"},{"v":1.39863223077365,"d":"1.40"},{"v":0.484016656862515,"d":"0.48"},{"v":0.76464333756086,"d":"0.76"},{"v":0.974133027758152,"d":"0.97"},"up","no"]
["MSTRG.7709","CAPS;VMAC;AC104532.1","ENST00000588776;ENST00000590428;ENST00000339485;ENST00000585541;ENST00000588891;ENST00000588865;ENST00000452990","GO:0005509(calcium ion binding);GO:0005737(cytoplasm);GO:0005509(calcium ion binding)","NA","NA","NA","calcyphosine [Source:HGNC Symbol;Acc:HGNC:1487];vimentin type intermediate filament associated coiled-coil protein [Source:HGNC Symbol;Acc:HGNC:33803]",{"v":1.18753705417714,"d":"1.19"},{"v":0.855588075062814,"d":"0.86"},{"v":1.3879775662955,"d":"1.39"},{"v":0.472984250008552,"d":"0.47"},{"v":0.766150647051477,"d":"0.77"},{"v":0.974543676674376,"d":"0.97"},"up","no"]
["MSTRG.10068","U2AF1","ENST00000475639;ENST00000496462;ENST00000291552;ENST00000478282;ENST00000380276;ENST00000471250;ENST00000464750;ENST00000463599;ENST00000398137;ENST00000459639","GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0006397(mRNA processing);GO:0008380(RNA splicing);GO:0005634(nucleus);GO:0016607(nuclear speck);GO:0046872(metal ion binding);GO:0005654(nucleoplasm);GO:0005515(protein binding);GO:0005681(spliceosomal complex);GO:0000398(mRNA splicing, via spliceosome);GO:0089701(U2AF);GO:0030628(pre-mRNA 3'-splice site binding);GO:0006369(termination of RNA polymerase II transcription);GO:0006405(RNA export from nucleus);GO:0031124(mRNA 3'-end processing);GO:1903146(regulation of mitophagy);GO:1903955(positive regulation of protein targeting to mitochondrion);GO:0006406(mRNA export from nucleus);GO:0071013(catalytic step 2 spliceosome);GO:0015030(Cajal body);GO:0015030(Cajal body)","03040(Spliceosome);05131(Shigellosis);05131(Shigellosis)","K12836","NA","U2 small nuclear RNA auxiliary factor 1 [Source:HGNC Symbol;Acc:HGNC:12453]",{"v":2.00677048173146,"d":"2.01"},{"v":1.90575157595392,"d":"1.91"},{"v":1.05300738409568,"d":"1.05"},{"v":0.0745155531355858,"d":"0.07"},{"v":0.767448051956072,"d":"0.77"},{"v":0.975211042261907,"d":"0.98"},"up","no"]
["ENSG00000076003","MCM6","ENST00000264156;ENST00000483902","GO:0005634(nucleus);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0005654(nucleoplasm);GO:0016787(hydrolase activity);GO:0003677(DNA binding);GO:0004386(helicase activity);GO:0005515(protein binding);GO:0006270(DNA replication initiation);GO:0007049(cell cycle);GO:0006260(DNA replication);GO:0042802(identical protein binding);GO:0003678(DNA helicase activity);GO:0042555(MCM complex);GO:0000784(nuclear chromosome, telomeric region);GO:0004003(ATP-dependent DNA helicase activity);GO:0000082(G1/S transition of mitotic cell cycle);GO:0003697(single-stranded DNA binding);GO:0006268(DNA unwinding involved in DNA replication);GO:0006268(DNA unwinding involved in DNA replication)","03030(DNA replication);04110(Cell cycle);04110(Cell cycle)","K02542","EC:3.6.4.12","minichromosome maintenance complex component 6 [Source:HGNC Symbol;Acc:HGNC:6949]",{"v":2.82182215614376,"d":"2.82"},{"v":2.68059451578436,"d":"2.68"},{"v":1.05268519335088,"d":"1.05"},{"v":0.0740740613448509,"d":"0.07"},{"v":0.770079722778237,"d":"0.77"},{"v":0.976082439631132,"d":"0.98"},"up","no"]
["ENSG00000123607","TTC21B","ENST00000243344;ENST00000476227;ENST00000464374;ENST00000497425;ENST00000484129;ENST00000392695;ENST00000486672","GO:0005737(cytoplasm);GO:0005856(cytoskeleton);GO:0042995(cell projection);GO:0035735(intraciliary transport involved in cilium assembly);GO:0005929(cilium);GO:0097542(ciliary tip);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0030991(intraciliary transport particle A);GO:0007224(smoothened signaling pathway);GO:0008589(regulation of smoothened signaling pathway);GO:0021591(ventricular system development);GO:0021798(forebrain dorsal/ventral pattern formation);GO:0035721(intraciliary retrograde transport);GO:0061512(protein localization to cilium);GO:0000790(nuclear chromatin);GO:0000790(nuclear chromatin)","NA","NA","NA","tetratricopeptide repeat domain 21B [Source:HGNC Symbol;Acc:HGNC:25660]",{"v":1.6165301790926,"d":"1.62"},{"v":1.17450445303794,"d":"1.17"},{"v":1.37635083026831,"d":"1.38"},{"v":0.460848258248886,"d":"0.46"},{"v":0.771356180971615,"d":"0.77"},{"v":0.976082439631132,"d":"0.98"},"up","no"]
["ENSG00000154856","APCDD1","ENST00000355285;ENST00000579685;ENST00000584596","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005886(plasma membrane);GO:0016055(Wnt signaling pathway);GO:0005887(integral component of plasma membrane);GO:0017147(Wnt-protein binding);GO:0030178(negative regulation of Wnt signaling pathway);GO:0001942(hair follicle development);GO:0043615(astrocyte cell migration);GO:0043615(astrocyte cell migration)","NA","NA","NA","APC down-regulated 1 [Source:HGNC Symbol;Acc:HGNC:15718]",{"v":0.174505093723709,"d":"0.17"},{"v":0.16649726737338,"d":"0.17"},{"v":1.04809584251236,"d":"1.05"},{"v":0.0677706493133612,"d":"0.07"},{"v":0.771823437296812,"d":"0.77"},{"v":0.976082439631132,"d":"0.98"},"up","no"]
["ENSG00000185803","SLC52A2","ENST00000532887;ENST00000527078;ENST00000530047;ENST00000533662;ENST00000526752;ENST00000526779;ENST00000534725;ENST00000526338;ENST00000329994","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005887(integral component of plasma membrane);GO:0032217(riboflavin transporter activity);GO:0032218(riboflavin transport);GO:0006810(transport);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0046718(viral entry into host cell);GO:0001618(virus receptor activity);GO:0006771(riboflavin metabolic process);GO:0006771(riboflavin metabolic process)","NA","NA","NA","solute carrier family 52 member 2 [Source:HGNC Symbol;Acc:HGNC:30224]",{"v":2.11326038790157,"d":"2.11"},{"v":1.52443443198906,"d":"1.52"},{"v":1.38625863045104,"d":"1.39"},{"v":0.471196442222991,"d":"0.47"},{"v":0.77386374930573,"d":"0.77"},{"v":0.976082439631132,"d":"0.98"},"up","no"]
["ENSG00000163577","EIF5A2","ENST00000295822","GO:0003723(RNA binding);GO:0006810(transport);GO:0051028(mRNA transport);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0015031(protein transport);GO:0043231(intracellular membrane-bounded organelle);GO:0006412(translation);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005515(protein binding);GO:0003746(translation elongation factor activity);GO:0006414(translational elongation);GO:0005643(nuclear pore);GO:0007283(spermatogenesis);GO:0043022(ribosome binding);GO:0005829(cytosol);GO:0006452(translational frameshifting);GO:0045901(positive regulation of translational elongation);GO:0045905(positive regulation of translational termination);GO:0008284(positive regulation of cell proliferation);GO:0008612(peptidyl-lysine modification to peptidyl-hypusine);GO:0010509(polyamine homeostasis)","NA","NA","NA","eukaryotic translation initiation factor 5A2 [Source:HGNC Symbol;Acc:HGNC:3301]",{"v":0.86044,"d":"0.86"},{"v":0.816818,"d":"0.82"},{"v":1.05340479764158,"d":"1.05"},{"v":0.075059935249992,"d":"0.08"},{"v":0.773959123594036,"d":"0.77"},{"v":0.976082439631132,"d":"0.98"},"up","no"]
["ENSG00000147883","CDKN2B","ENST00000276925;ENST00000380142","GO:0008285(negative regulation of cell proliferation);GO:0005737(cytoplasm);GO:0050680(negative regulation of epithelial cell proliferation);GO:0005634(nucleus);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0005515(protein binding);GO:0007049(cell cycle);GO:0071901(negative regulation of protein serine/threonine kinase activity);GO:0005829(cytosol);GO:0048536(spleen development);GO:2000134(negative regulation of G1/S transition of mitotic cell cycle);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0019901(protein kinase binding);GO:0007093(mitotic cell cycle checkpoint);GO:0030511(positive regulation of transforming growth factor beta receptor signaling pathway);GO:0030219(megakaryocyte differentiation);GO:0007050(cell cycle arrest);GO:0004861(cyclin-dependent protein serine/threonine kinase inhibitor activity);GO:0000086(G2/M transition of mitotic cell cycle);GO:0031668(cellular response to extracellular stimulus);GO:0042326(negative regulation of phosphorylation);GO:0000079(regulation of cyclin-dependent protein serine/threonine kinase activity);GO:0031670(cellular response to nutrient);GO:0031670(cellular response to nutrient)","04350(TGF-beta signaling pathway);04068(FoxO signaling pathway);04110(Cell cycle);04218(Cellular senescence);05200(Pathways in cancer);05203(Viral carcinogenesis);05226(Gastric cancer);05222(Small cell lung cancer);05166(HTLV-I infection);05166(HTLV-I infection)","K04685","NA","cyclin dependent kinase inhibitor 2B [Source:HGNC Symbol;Acc:HGNC:1788]",{"v":0.532274635781173,"d":"0.53"},{"v":0.512399790290784,"d":"0.51"},{"v":1.0387877705397,"d":"1.04"},{"v":0.0549009346414875,"d":"0.05"},{"v":0.775369026573425,"d":"0.78"},{"v":0.976082439631132,"d":"0.98"},"up","no"]
["ENSG00000149292","TTC12","ENST00000480233;ENST00000464224;ENST00000429951;ENST00000462711;ENST00000527781;ENST00000489064;ENST00000478125;ENST00000525989;ENST00000442859;ENST00000393020;ENST00000494714;ENST00000496311;ENST00000529221;ENST00000483239","GO:0005813(centrosome);GO:0005813(centrosome)","NA","NA","NA","tetratricopeptide repeat domain 12 [Source:HGNC Symbol;Acc:HGNC:23700]",{"v":0.830612439079593,"d":"0.83"},{"v":0.784607834024896,"d":"0.78"},{"v":1.05863388441931,"d":"1.06"},{"v":0.0822037371520616,"d":"0.08"},{"v":0.776396526436825,"d":"0.78"},{"v":0.976211873268823,"d":"0.98"},"up","no"]
["MSTRG.826","ATP1A1","ENST00000295598;ENST00000495965;ENST00000491156;ENST00000488733;ENST00000537345;ENST00000463382;ENST00000369496;ENST00000369494;ENST00000479960","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0006810(transport);GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0016787(hydrolase activity);GO:0016311(dephosphorylation);GO:0006811(ion transport);GO:0006813(potassium ion transport);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0006814(sodium ion transport);GO:0042470(melanosome);GO:0005391(sodium:potassium-exchanging ATPase activity);GO:0010248(establishment or maintenance of transmembrane electrochemical gradient);GO:0070062(extracellular exosome);GO:0034220(ion transmembrane transport);GO:0043234(protein complex);GO:0005783(endoplasmic reticulum);GO:1903779(regulation of cardiac conduction);GO:0005890(sodium:potassium-exchanging ATPase complex);GO:0042383(sarcolemma);GO:1903561(extracellular vesicle);GO:0051087(chaperone binding);GO:0002028(regulation of sodium ion transport);GO:0086002(cardiac muscle cell action potential involved in contraction);GO:0010107(potassium ion import);GO:0005794(Golgi apparatus);GO:0030955(potassium ion binding);GO:0031402(sodium ion binding);GO:1990239(steroid hormone binding);GO:0006883(cellular sodium ion homeostasis);GO:0030007(cellular potassium ion homeostasis);GO:0036376(sodium ion export from cell);GO:0055119(relaxation of cardiac muscle);GO:0071383(cellular response to steroid hormone stimulus);GO:0086009(membrane repolarization);GO:0086013(membrane repolarization during cardiac muscle cell action potential);GO:0086064(cell communication by electrical coupling involved in cardiac conduction);GO:1903416(response to glycoside);GO:1990573(potassium ion import across plasma membrane);GO:0016791(phosphatase activity);GO:0019901(protein kinase binding);GO:0019904(protein domain specific binding);GO:0030506(ankyrin binding);GO:0043531(ADP binding);GO:0043548(phosphatidylinositol 3-kinase binding);GO:0002026(regulation of the force of heart contraction);GO:0008217(regulation of blood pressure);GO:0031947(negative regulation of glucocorticoid biosynthetic process);GO:0042493(response to drug);GO:0045822(negative regulation of heart contraction);GO:0045823(positive regulation of heart contraction);GO:0045989(positive regulation of striated muscle contraction);GO:0060081(membrane hyperpolarization);GO:0071260(cellular response to mechanical stimulus);GO:0086004(regulation of cardiac muscle cell contraction);GO:0090662(ATP hydrolysis coupled transmembrane transport);GO:0005768(endosome);GO:0005901(caveola);GO:0014069(postsynaptic density);GO:0014704(intercalated disc);GO:0016323(basolateral plasma membrane);GO:0016324(apical plasma membrane);GO:0030315(T-tubule);GO:0043209(myelin sheath);GO:0045121(membrane raft);GO:0045121(membrane raft)","04024(cAMP signaling pathway);04022(cGMP - PKG signaling pathway);04911(Insulin secretion);04918(Thyroid hormone synthesis);04919(Thyroid hormone signaling pathway);04925(Aldosterone synthesis and secretion);04260(Cardiac muscle contraction);04261(Adrenergic signaling in cardiomyocytes);04970(Salivary secretion);04971(Gastric acid secretion);04972(Pancreatic secretion);04976(Bile secretion);04973(Carbohydrate digestion and absorption);04974(Protein digestion and absorption);04978(Mineral absorption);04960(Aldosterone-regulated sodium reabsorption);04961(Endocrine and other factor-regulated calcium reabsorption);04964(Proximal tubule bicarbonate reclamation);04964(Proximal tubule bicarbonate reclamation)","K01539","EC:3.6.3.9","ATPase Na+/K+ transporting subunit alpha 1 [Source:HGNC Symbol;Acc:HGNC:799]",{"v":23.6787569223248,"d":"23.68"},{"v":17.2807306153422,"d":"17.28"},{"v":1.3702404978932,"d":"1.37"},{"v":0.454429130169216,"d":"0.45"},{"v":0.777648039507266,"d":"0.78"},{"v":0.976289160502893,"d":"0.98"},"up","no"]
["MSTRG.5932","AMFR","ENST00000290649;ENST00000568657;ENST00000566334;ENST00000568762;ENST00000568325;ENST00000563285;ENST00000567738;ENST00000566757","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005794(Golgi apparatus);GO:0046872(metal ion binding);GO:0005783(endoplasmic reticulum);GO:0016740(transferase activity);GO:0016567(protein ubiquitination);GO:0005789(endoplasmic reticulum membrane);GO:0005515(protein binding);GO:0044322(endoplasmic reticulum quality control compartment);GO:0006511(ubiquitin-dependent protein catabolic process);GO:1904264(ubiquitin protein ligase activity involved in ERAD pathway);GO:0000209(protein polyubiquitination);GO:0030433(ubiquitin-dependent ERAD pathway);GO:0004872(receptor activity);GO:0042787(protein ubiquitination involved in ubiquitin-dependent protein catabolic process);GO:0006457(protein folding);GO:0043234(protein complex);GO:0030176(integral component of endoplasmic reticulum membrane);GO:0007165(signal transduction);GO:0004842(ubiquitin-protein transferase activity);GO:1904380(endoplasmic reticulum mannose trimming);GO:0051259(protein oligomerization);GO:0006928(movement of cell or subcellular component);GO:0048471(perinuclear region of cytoplasm);GO:1904288(BAT3 complex binding);GO:0051087(chaperone binding);GO:0061630(ubiquitin protein ligase activity);GO:1990381(ubiquitin-specific protease binding);GO:0032092(positive regulation of protein binding);GO:0036503(ERAD pathway);GO:0051865(protein autoubiquitination);GO:0070936(protein K48-linked ubiquitination);GO:0030968(endoplasmic reticulum unfolded protein response);GO:0030674(protein binding, bridging);GO:0036513(Derlin-1 retrotranslocation complex);GO:0034450(ubiquitin-ubiquitin ligase activity);GO:0007568(aging);GO:0007611(learning or memory);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0030425(dendrite);GO:0030426(growth cone);GO:0043025(neuronal cell body);GO:0043025(neuronal cell body)","04141(Protein processing in endoplasmic reticulum);04141(Protein processing in endoplasmic reticulum)","K10636","EC:2.3.2.27","autocrine motility factor receptor [Source:HGNC Symbol;Acc:HGNC:463]",{"v":7.82018302396666,"d":"7.82"},{"v":7.36524276693296,"d":"7.37"},{"v":1.0617685351902,"d":"1.06"},{"v":0.0864692938923644,"d":"0.09"},{"v":0.779986171270587,"d":"0.78"},{"v":0.977285551437577,"d":"0.98"},"up","no"]
["MSTRG.11937","CASP3","ENST00000523916;ENST00000308394;ENST00000393588;ENST00000447121;ENST00000517513;ENST00000393585","GO:0005737(cytoplasm);GO:0006915(apoptotic process);GO:0008234(cysteine-type peptidase activity);GO:0006508(proteolysis);GO:0004197(cysteine-type endopeptidase activity);GO:0005634(nucleus);GO:0016787(hydrolase activity);GO:0005829(cytosol);GO:0005515(protein binding);GO:0008233(peptidase activity);GO:0030218(erythrocyte differentiation);GO:0005886(plasma membrane);GO:0005654(nucleoplasm);GO:0030182(neuron differentiation);GO:0006919(activation of cysteine-type endopeptidase activity involved in apoptotic process);GO:0006309(apoptotic DNA fragmentation);GO:0097194(execution phase of apoptosis);GO:0030216(keratinocyte differentiation);GO:0035329(hippo signaling);GO:0034612(response to tumor necrosis factor);GO:0008635(activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c);GO:0016241(regulation of macroautophagy);GO:0030220(platelet formation);GO:0004190(aspartic-type endopeptidase activity);GO:0043066(negative regulation of apoptotic process);GO:0002020(protease binding);GO:0004861(cyclin-dependent protein serine/threonine kinase inhibitor activity);GO:0005123(death receptor binding);GO:0008656(cysteine-type endopeptidase activator activity involved in apoptotic process);GO:0016005(phospholipase A2 activator activity);GO:0032403(protein complex binding);GO:0097153(cysteine-type endopeptidase activity involved in apoptotic process);GO:0097200(cysteine-type endopeptidase activity involved in execution phase of apoptosis);GO:0001666(response to hypoxia);GO:0001782(B cell homeostasis);GO:0006974(cellular response to DNA damage stimulus);GO:0007507(heart development);GO:0007605(sensory perception of sound);GO:0007611(learning or memory);GO:0008627(intrinsic apoptotic signaling pathway in response to osmotic stress);GO:0009411(response to UV);GO:0009611(response to wounding);GO:0009749(response to glucose);GO:0010033(response to organic substance);GO:0010038(response to metal ion);GO:0010165(response to X-ray);GO:0014070(response to organic cyclic compound);GO:0016485(protein processing);GO:0021766(hippocampus development);GO:0030889(negative regulation of B cell proliferation);GO:0032025(response to cobalt ion);GO:0032355(response to estradiol);GO:0032496(response to lipopolysaccharide);GO:0034349(glial cell apoptotic process);GO:0035094(response to nicotine);GO:0035556(intracellular signal transduction);GO:0042060(wound healing);GO:0042493(response to drug);GO:0042542(response to hydrogen peroxide);GO:0043029(T cell homeostasis);GO:0043065(positive regulation of apoptotic process);GO:0043200(response to amino acid);GO:0043525(positive regulation of neuron apoptotic process);GO:0045165(cell fate commitment);GO:0045736(negative regulation of cyclin-dependent protein serine/threonine kinase activity);GO:0045786(negative regulation of cell cycle);GO:0046007(negative regulation of activated T cell proliferation);GO:0046677(response to antibiotic);GO:0048011(neurotrophin TRK receptor signaling pathway);GO:0051384(response to glucocorticoid);GO:0051402(neuron apoptotic process);GO:0071310(cellular response to organic substance);GO:0071407(cellular response to organic cyclic compound);GO:0072734(cellular response to staurosporine);GO:0097190(apoptotic signaling pathway);GO:0097192(extrinsic apoptotic signaling pathway in absence of ligand);GO:0031264(death-inducing signaling complex);GO:0045121(membrane raft);GO:0045121(membrane raft)","04010(MAPK signaling pathway);04668(TNF signaling pathway);04210(Apoptosis);04215(Apoptosis - multiple species);04115(p53 signaling pathway);04650(Natural killer cell mediated cytotoxicity);04657(IL-17 signaling pathway);04726(Serotonergic synapse);05200(Pathways in cancer);05206(MicroRNAs in cancer);05205(Proteoglycans in cancer);05203(Viral carcinogenesis);05210(Colorectal cancer);05222(Small cell lung cancer);05010(Alzheimer's disease);05012(Parkinson's disease);05014(Amyotrophic lateral sclerosis (ALS));05016(Huntington's disease);05416(Viral myocarditis);04932(Non-alcoholic fatty liver disease (NAFLD));04933(AGE-RAGE signaling pathway in diabetic complications);05120(Epithelial cell signaling in Helicobacter pylori infection);05133(Pertussis);05134(Legionellosis);05152(Tuberculosis);05161(Hepatitis B);05168(Herpes simplex infection);05167(Kaposi's sarcoma-associated herpesvirus infection);05165(Human papillomavirus infection);05146(Amoebiasis);05145(Toxoplasmosis);01524(Platinum drug resistance);01524(Platinum drug resistance)","K02187","EC:3.4.22.56","caspase 3 [Source:HGNC Symbol;Acc:HGNC:1504]",{"v":9.54150723180407,"d":"9.54"},{"v":9.00158082028286,"d":"9.00"},{"v":1.05998128798717,"d":"1.06"},{"v":0.0840387968956562,"d":"0.08"},{"v":0.780458040694118,"d":"0.78"},{"v":0.977363351705046,"d":"0.98"},"up","no"]
["ENSG00000198382","UVRAG","ENST00000356136;ENST00000531818;ENST00000533454;ENST00000530501;ENST00000525183","GO:0005694(chromosome);GO:0005783(endoplasmic reticulum);GO:0005515(protein binding);GO:0006281(DNA repair);GO:0006974(cellular response to DNA damage stimulus);GO:0005764(lysosome);GO:0005813(centrosome);GO:0030496(midbody);GO:0000775(chromosome, centromeric region);GO:0005768(endosome);GO:0005769(early endosome);GO:0005770(late endosome);GO:0007098(centrosome cycle);GO:0000149(SNARE binding);GO:0010508(positive regulation of autophagy);GO:0005737(cytoplasm);GO:0032465(regulation of cytokinesis);GO:0006914(autophagy);GO:0032801(receptor catabolic process);GO:0071985(multivesicular body sorting pathway);GO:1901098(positive regulation of autophagosome maturation);GO:0030897(HOPS complex);GO:0070418(DNA-dependent protein kinase complex);GO:0017124(SH3 domain binding);GO:0006890(retrograde vesicle-mediated transport, Golgi to ER);GO:0007051(spindle organization);GO:0007059(chromosome segregation);GO:0035493(SNARE complex assembly);GO:0046718(viral entry into host cell);GO:0051684(maintenance of Golgi location);GO:0060627(regulation of vesicle-mediated transport);GO:0071900(regulation of protein serine/threonine kinase activity);GO:0097680(double-strand break repair via classical nonhomologous end joining);GO:0043234(protein complex);GO:0045335(phagocytic vesicle);GO:0045335(phagocytic vesicle)","04140(Autophagy - animal);04140(Autophagy - animal)","K21249","NA","UV radiation resistance associated [Source:HGNC Symbol;Acc:HGNC:12640]",{"v":1.76287749448992,"d":"1.76"},{"v":1.28860726306675,"d":"1.29"},{"v":1.36804870267024,"d":"1.37"},{"v":0.452119591225373,"d":"0.45"},{"v":0.781881172544479,"d":"0.78"},{"v":0.977722634930554,"d":"0.98"},"up","no"]
["ENSG00000204789","ZNF204P","ENST00000416749","NA","NA","NA","NA","zinc finger protein 204, pseudogene [Source:HGNC Symbol;Acc:HGNC:12995]",{"v":0.637604,"d":"0.64"},{"v":0.602285,"d":"0.60"},{"v":1.05864167296214,"d":"1.06"},{"v":0.0822143512566629,"d":"0.08"},{"v":0.783894788963968,"d":"0.78"},{"v":0.977794940715011,"d":"0.98"},"up","no"]
["ENSG00000197776","KLHDC1","ENST00000359332;ENST00000555704","GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005829(cytosol)","NA","NA","NA","kelch domain containing 1 [Source:HGNC Symbol;Acc:HGNC:19836]",{"v":0.423700904191617,"d":"0.42"},{"v":0.303228074850299,"d":"0.30"},{"v":1.39730103949245,"d":"1.40"},{"v":0.482642873571328,"d":"0.48"},{"v":0.784380331708794,"d":"0.78"},{"v":0.977794940715011,"d":"0.98"},"up","no"]
["ENSG00000111554","MDM1","ENST00000303145;ENST00000430606;ENST00000411698;ENST00000538454;ENST00000540418;ENST00000541686;ENST00000545964;ENST00000357874;ENST00000536313;ENST00000393543;ENST00000541087;ENST00000536997","GO:0008017(microtubule binding);GO:0046600(negative regulation of centriole replication);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005813(centrosome);GO:0005856(cytoskeleton);GO:0005874(microtubule);GO:0005815(microtubule organizing center);GO:0005814(centriole);GO:0060041(retina development in camera-type eye);GO:0060041(retina development in camera-type eye)","NA","NA","NA","Mdm1 nuclear protein [Source:HGNC Symbol;Acc:HGNC:29917]",{"v":2.22934149992365,"d":"2.23"},{"v":2.09373002916476,"d":"2.09"},{"v":1.06477027547481,"d":"1.06"},{"v":0.0905422021103301,"d":"0.09"},{"v":0.786977394870004,"d":"0.79"},{"v":0.978775907967264,"d":"0.98"},"up","no"]
["MSTRG.15430","CUL4B","ENST00000371322;ENST00000336592;ENST00000497616;ENST00000371323;ENST00000467641;ENST00000404115","GO:0005634(nucleus);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0016567(protein ubiquitination);GO:0005515(protein binding);GO:0006281(DNA repair);GO:0006974(cellular response to DNA damage stimulus);GO:0007049(cell cycle);GO:0006511(ubiquitin-dependent protein catabolic process);GO:0031625(ubiquitin protein ligase binding);GO:0031461(cullin-RING ubiquitin ligase complex);GO:0061630(ubiquitin protein ligase activity);GO:0070062(extracellular exosome);GO:0043687(post-translational protein modification);GO:0042787(protein ubiquitination involved in ubiquitin-dependent protein catabolic process);GO:0010498(proteasomal protein catabolic process);GO:0006283(transcription-coupled nucleotide-excision repair);GO:0003684(damaged DNA binding);GO:0042769(DNA damage response, detection of DNA damage);GO:0035518(histone H2A monoubiquitination);GO:0006293(nucleotide-excision repair, preincision complex stabilization);GO:0006295(nucleotide-excision repair, DNA incision, 3'-to lesion);GO:0006296(nucleotide-excision repair, DNA incision, 5'-to lesion);GO:0033683(nucleotide-excision repair, DNA incision);GO:0070911(global genome nucleotide-excision repair);GO:0000715(nucleotide-excision repair, DNA damage recognition);GO:0000717(nucleotide-excision repair, DNA duplex unwinding);GO:0006294(nucleotide-excision repair, preincision complex assembly);GO:0031465(Cul4B-RING E3 ubiquitin ligase complex);GO:0070914(UV-damage excision repair);GO:0031175(neuron projection development);GO:0045732(positive regulation of protein catabolic process);GO:1900087(positive regulation of G1/S transition of mitotic cell cycle);GO:1900087(positive regulation of G1/S transition of mitotic cell cycle)","04120(Ubiquitin mediated proteolysis);03420(Nucleotide excision repair);03420(Nucleotide excision repair)","K10609","NA","cullin 4B [Source:HGNC Symbol;Acc:HGNC:2555]",{"v":9.81584516640592,"d":"9.82"},{"v":7.20822060759494,"d":"7.21"},{"v":1.36175704112933,"d":"1.36"},{"v":0.445469326826676,"d":"0.45"},{"v":0.788304605611237,"d":"0.79"},{"v":0.978775907967264,"d":"0.98"},"up","no"]
["MSTRG.7239","SRP68","ENST00000307877;ENST00000586859;ENST00000585539;ENST00000588643;ENST00000539137;ENST00000602720;ENST00000591272;ENST00000587864;ENST00000590833;ENST00000542536;ENST00000592704;ENST00000588736","GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0030529(intracellular ribonucleoprotein complex);GO:0005925(focal adhesion);GO:0008312(7S RNA binding);GO:0006614(SRP-dependent cotranslational protein targeting to membrane);GO:0005730(nucleolus);GO:0005515(protein binding);GO:0005786(signal recognition particle, endoplasmic reticulum targeting);GO:0030942(endoplasmic reticulum signal peptide binding);GO:0005783(endoplasmic reticulum);GO:0019904(protein domain specific binding);GO:0045047(protein targeting to ER);GO:0043022(ribosome binding);GO:0005047(signal recognition particle binding);GO:0042493(response to drug);GO:0048500(signal recognition particle);GO:0005840(ribosome);GO:0005840(ribosome)","03060(Protein export);03060(Protein export)","K03107","NA","signal recognition particle 68 [Source:HGNC Symbol;Acc:HGNC:11302]",{"v":3.24390251878026,"d":"3.24"},{"v":3.03949109357414,"d":"3.04"},{"v":1.06725185858852,"d":"1.07"},{"v":0.0939006749998021,"d":"0.09"},{"v":0.789415387607438,"d":"0.79"},{"v":0.978775907967264,"d":"0.98"},"up","no"]
["MSTRG.15462","SLC9A6","ENST00000636206;ENST00000370695;ENST00000636347;ENST00000638078;ENST00000626147;ENST00000630721;ENST00000636625;ENST00000637581","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0043231(intracellular membrane-bounded organelle);GO:0055085(transmembrane transport);GO:0005789(endoplasmic reticulum membrane);GO:0006811(ion transport);GO:0005886(plasma membrane);GO:0015297(antiporter activity);GO:0015299(solute:proton antiporter activity);GO:0015385(sodium:proton antiporter activity);GO:0006812(cation transport);GO:0006814(sodium ion transport);GO:0006885(regulation of pH);GO:1902600(hydrogen ion transmembrane transport);GO:0005768(endosome);GO:0010008(endosome membrane);GO:0031901(early endosome membrane);GO:0055038(recycling endosome membrane);GO:0051453(regulation of intracellular pH);GO:0048812(neuron projection morphogenesis);GO:0015386(potassium:proton antiporter activity);GO:0071805(potassium ion transmembrane transport);GO:0098719(sodium ion import across plasma membrane);GO:0048675(axon extension);GO:0097484(dendrite extension);GO:0035725(sodium ion transmembrane transport);GO:0015992(proton transport);GO:0031547(brain-derived neurotrophic factor receptor signaling pathway);GO:0050808(synapse organization);GO:0051386(regulation of neurotrophin TRK receptor signaling pathway);GO:0060996(dendritic spine development);GO:0005769(early endosome);GO:0005770(late endosome);GO:0030425(dendrite);GO:0031410(cytoplasmic vesicle);GO:0043679(axon terminus);GO:0044308(axonal spine);GO:0045202(synapse);GO:0055037(recycling endosome);GO:0055037(recycling endosome)","04260(Cardiac muscle contraction);04260(Cardiac muscle contraction)","K12041","NA","solute carrier family 9 member A6 [Source:HGNC Symbol;Acc:HGNC:11079]",{"v":2.32641690344635,"d":"2.33"},{"v":1.70669229747454,"d":"1.71"},{"v":1.36311443304036,"d":"1.36"},{"v":0.446906681035221,"d":"0.45"},{"v":0.789770236434768,"d":"0.79"},{"v":0.978775907967264,"d":"0.98"},"up","no"]
["MSTRG.11524","TBC1D14","MSTRG.11524.3;ENST00000409757;ENST00000451522;ENST00000410031;ENST00000448507;ENST00000467966;ENST00000439515;ENST00000446947;ENST00000427736","GO:0010507(negative regulation of autophagy);GO:0005794(Golgi apparatus);GO:0005829(cytosol);GO:0043231(intracellular membrane-bounded organelle);GO:0005654(nucleoplasm);GO:0005515(protein binding);GO:0005096(GTPase activator activity);GO:0017137(Rab GTPase binding);GO:0006886(intracellular protein transport);GO:0031338(regulation of vesicle fusion);GO:0090630(activation of GTPase activity);GO:0061024(membrane organization);GO:0055037(recycling endosome);GO:0019901(protein kinase binding);GO:0005776(autophagosome);GO:0071955(recycling endosome to Golgi transport);GO:2000785(regulation of autophagosome assembly);GO:2000785(regulation of autophagosome assembly)","NA","NA","NA","TBC1 domain family member 14 [Source:HGNC Symbol;Acc:HGNC:29246]",{"v":18.5602532591415,"d":"18.56"},{"v":13.6560265945946,"d":"13.66"},{"v":1.35912544769707,"d":"1.36"},{"v":0.442678623447332,"d":"0.44"},{"v":0.791249588316026,"d":"0.79"},{"v":0.978775907967264,"d":"0.98"},"up","no"]
["MSTRG.2610","CARNS1","ENST00000531388;ENST00000445895;ENST00000531958","GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0003824(catalytic activity);GO:0016874(ligase activity);GO:0016887(ATPase activity);GO:0005575(cellular_component);GO:0005829(cytosol);GO:0047730(carnosine synthase activity);GO:0102102(-);GO:0006548(histidine catabolic process);GO:0035499(carnosine biosynthetic process);GO:0035499(carnosine biosynthetic process)","00330(Arginine and proline metabolism);00340(Histidine metabolism);00410(beta-Alanine metabolism);00410(beta-Alanine metabolism)","K14755","EC:6.3.2.11","carnosine synthase 1 [Source:HGNC Symbol;Acc:HGNC:29268]",{"v":0.698244641975309,"d":"0.70"},{"v":0.50907477372134,"d":"0.51"},{"v":1.37159544730755,"d":"1.37"},{"v":0.455855020703094,"d":"0.46"},{"v":0.792191397841464,"d":"0.79"},{"v":0.979135211853443,"d":"0.98"},"up","no"]
["ENSG00000273513","TBC1D3K","ENST00000620247","GO:0016020(membrane);GO:0005886(plasma membrane);GO:0005096(GTPase activator activity);GO:0017137(Rab GTPase binding);GO:0006886(intracellular protein transport);GO:0031338(regulation of vesicle fusion);GO:0090630(activation of GTPase activity);GO:0005622(intracellular);GO:0012505(endomembrane system)","NA","NA","NA","TBC1 domain family member 3K [Source:HGNC Symbol;Acc:HGNC:51245]",{"v":0.565017,"d":"0.57"},{"v":0.411985,"d":"0.41"},{"v":1.37145041688411,"d":"1.37"},{"v":0.455702464250725,"d":"0.46"},{"v":0.793313508834652,"d":"0.79"},{"v":0.979135211853443,"d":"0.98"},"up","no"]
["MSTRG.8000","KXD1","ENST00000595073;ENST00000595870;ENST00000602094;ENST00000222307;ENST00000539106;ENST00000596785;ENST00000598830;ENST00000540691;ENST00000600654;ENST00000601630;ENST00000599000;ENST00000600796;ENST00000600372;ENST00000596244;ENST00000597438;ENST00000600099","GO:0016020(membrane);GO:0005765(lysosomal membrane);GO:0005515(protein binding);GO:0005764(lysosome);GO:0016192(vesicle-mediated transport);GO:0032418(lysosome localization);GO:0031083(BLOC-1 complex);GO:0099078(BORC complex);GO:0099078(BORC complex)","NA","NA","NA","KxDL motif containing 1 [Source:HGNC Symbol;Acc:HGNC:28420]",{"v":6.57895172300584,"d":"6.58"},{"v":6.13698799246109,"d":"6.14"},{"v":1.07201639160573,"d":"1.07"},{"v":0.100326965410895,"d":"0.10"},{"v":0.795426773648782,"d":"0.80"},{"v":0.979185247705156,"d":"0.98"},"up","no"]
["ENSG00000164951","PDP1","ENST00000297598;ENST00000518107;ENST00000396200;ENST00000517764;ENST00000518573;ENST00000520728;ENST00000521144;ENST00000520614;ENST00000518827","GO:0046872(metal ion binding);GO:0016787(hydrolase activity);GO:0003824(catalytic activity);GO:0006470(protein dephosphorylation);GO:0005739(mitochondrion);GO:0004721(phosphoprotein phosphatase activity);GO:0005515(protein binding);GO:0005759(mitochondrial matrix);GO:0004722(protein serine/threonine phosphatase activity);GO:0043169(cation binding);GO:0010510(regulation of acetyl-CoA biosynthetic process from pyruvate);GO:0035970(peptidyl-threonine dephosphorylation);GO:0004741([pyruvate dehydrogenase (lipoamide)] phosphatase activity);GO:0004741([pyruvate dehydrogenase (lipoamide)] phosphatase activity)","NA","NA","NA","pyruvate dehyrogenase phosphatase catalytic subunit 1 [Source:HGNC Symbol;Acc:HGNC:9279]",{"v":3.52972900196323,"d":"3.53"},{"v":2.60197035177583,"d":"2.60"},{"v":1.35656003903127,"d":"1.36"},{"v":0.439952900252189,"d":"0.44"},{"v":0.796910513280673,"d":"0.80"},{"v":0.979185247705156,"d":"0.98"},"up","no"]
["MSTRG.10830","WDR48","ENST00000302313;ENST00000477197;ENST00000423296;ENST00000463198;ENST00000433841;ENST00000441361;ENST00000420940;ENST00000466405;ENST00000489838","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0043231(intracellular membrane-bounded organelle);GO:0000724(double-strand break repair via homologous recombination);GO:0006974(cellular response to DNA damage stimulus);GO:0007283(spermatogenesis);GO:0007338(single fertilization);GO:0008584(male gonad development);GO:0035264(multicellular organism growth);GO:0043588(skin development);GO:0048568(embryonic organ development);GO:0048705(skeletal system morphogenesis);GO:0048872(homeostasis of number of cells);GO:0050679(positive regulation of epithelial cell proliferation);GO:0072520(seminiferous tubule development);GO:1902525(regulation of protein monoubiquitination);GO:0005764(lysosome);GO:0005515(protein binding);GO:0005768(endosome);GO:0005654(nucleoplasm);GO:0016579(protein deubiquitination);GO:0016032(viral process);GO:0005770(late endosome);GO:0036459(thiol-dependent ubiquitinyl hydrolase activity);GO:0036459(thiol-dependent ubiquitinyl hydrolase activity)","03460(Fanconi anemia pathway);03460(Fanconi anemia pathway)","K15361","NA","WD repeat domain 48 [Source:HGNC Symbol;Acc:HGNC:30914]",{"v":4.61440486151175,"d":"4.61"},{"v":4.30628340625,"d":"4.31"},{"v":1.0715515970952,"d":"1.07"},{"v":0.0997013199922119,"d":"0.10"},{"v":0.79755619328041,"d":"0.80"},{"v":0.979185247705156,"d":"0.98"},"up","no"]
["ENSG00000112031","MTRF1L","ENST00000367233;ENST00000464135;ENST00000485512;ENST00000448966;ENST00000414771;ENST00000482526;ENST00000367230;ENST00000367231;ENST00000461949","GO:0003747(translation release factor activity);GO:0006415(translational termination);GO:0006412(translation);GO:0005739(mitochondrion);GO:0005759(mitochondrial matrix);GO:0070126(mitochondrial translational termination);GO:0070126(mitochondrial translational termination)","NA","NA","NA","mitochondrial translational release factor 1 like [Source:HGNC Symbol;Acc:HGNC:21051]",{"v":1.82277170489118,"d":"1.82"},{"v":1.3418145813246,"d":"1.34"},{"v":1.35843784250115,"d":"1.36"},{"v":0.441948554248218,"d":"0.44"},{"v":0.798077151926847,"d":"0.80"},{"v":0.979185247705156,"d":"0.98"},"up","no"]
["ENSG00000177225","GATD1","ENST00000319863;ENST00000532839;ENST00000530209;ENST00000465313;ENST00000528602;ENST00000533960;ENST00000529966;ENST00000524550;ENST00000526325;ENST00000529362;ENST00000528309;ENST00000532320;ENST00000526650","GO:0005576(extracellular region);GO:0003674(molecular_function);GO:0008150(biological_process);GO:0070062(extracellular exosome);GO:0070062(extracellular exosome)","NA","NA","NA","glutamine amidotransferase like class 1 domain containing 1 [Source:HGNC Symbol;Acc:HGNC:26616]",{"v":2.22601189528131,"d":"2.23"},{"v":1.63456996134301,"d":"1.63"},{"v":1.36183335551594,"d":"1.36"},{"v":0.445550174803875,"d":"0.45"},{"v":0.799343160251152,"d":"0.80"},{"v":0.979185247705156,"d":"0.98"},"up","no"]
["MSTRG.3933","LINC00426","ENST00000447147;ENST00000452659;ENST00000429808;ENST00000416261;ENST00000417079;ENST00000420219;ENST00000420210","NA","NA","NA","NA","long intergenic non-protein coding RNA 426 [Source:HGNC Symbol;Acc:HGNC:42761]",{"v":0.798233734390735,"d":"0.80"},{"v":0.583684510070493,"d":"0.58"},{"v":1.36757738233336,"d":"1.37"},{"v":0.451622468081865,"d":"0.45"},{"v":0.800763366066381,"d":"0.80"},{"v":0.979185247705156,"d":"0.98"},"up","no"]
["ENSG00000162623","TYW3","ENST00000370867;ENST00000457880;ENST00000485401;ENST00000483990;ENST00000449696;ENST00000479111","GO:0008168(methyltransferase activity);GO:0016740(transferase activity);GO:0008033(tRNA processing);GO:0032259(methylation);GO:0032259(methylation)","NA","NA","NA","tRNA-yW synthesizing protein 3 homolog [Source:HGNC Symbol;Acc:HGNC:24757]",{"v":2.32042549263432,"d":"2.32"},{"v":1.71720319540728,"d":"1.72"},{"v":1.35128183947035,"d":"1.35"},{"v":0.434328611747023,"d":"0.43"},{"v":0.801668836640479,"d":"0.80"},{"v":0.979185247705156,"d":"0.98"},"up","no"]
["ENSG00000143537","ADAM15","ENST00000355956;ENST00000271836;ENST00000472434;ENST00000531831;ENST00000534019;ENST00000447332;ENST00000470779;ENST00000356955;ENST00000527418;ENST00000526491;ENST00000368413;ENST00000359280;ENST00000449910;ENST00000480331;ENST00000360674;ENST00000461564;ENST00000533732;ENST00000525020;ENST00000529473;ENST00000468053;ENST00000464824","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0046872(metal ion binding);GO:0016787(hydrolase activity);GO:0007155(cell adhesion);GO:0042995(cell projection);GO:0005515(protein binding);GO:0008233(peptidase activity);GO:0006508(proteolysis);GO:0030054(cell junction);GO:0004222(metalloendopeptidase activity);GO:0008237(metallopeptidase activity);GO:0031410(cytoplasmic vesicle);GO:0007229(integrin-mediated signaling pathway);GO:0045087(innate immune response);GO:0005886(plasma membrane);GO:0070062(extracellular exosome);GO:0012505(endomembrane system);GO:0005912(adherens junction);GO:0001669(acrosomal vesicle);GO:0017124(SH3 domain binding);GO:0009986(cell surface);GO:0030308(negative regulation of cell growth);GO:0005178(integrin binding);GO:0030198(extracellular matrix organization);GO:0001525(angiogenesis);GO:0022617(extracellular matrix disassembly);GO:0001953(negative regulation of cell-matrix adhesion);GO:0030574(collagen catabolic process);GO:0030336(negative regulation of cell migration);GO:0007160(cell-matrix adhesion);GO:0070528(protein kinase C signaling);GO:1900121(negative regulation of receptor binding);GO:0008584(male gonad development);GO:0042246(tissue regeneration);GO:0060317(cardiac epithelial to mesenchymal transition);GO:0005615(extracellular space);GO:0005615(extracellular space)","NA","NA","NA","ADAM metallopeptidase domain 15 [Source:HGNC Symbol;Acc:HGNC:193]",{"v":3.13830283869988,"d":"3.14"},{"v":2.92072491843864,"d":"2.92"},{"v":1.07449449240757,"d":"1.07"},{"v":0.10365808788748,"d":"0.10"},{"v":0.802638998522461,"d":"0.80"},{"v":0.979185247705156,"d":"0.98"},"up","no"]
["MSTRG.1427","ACBD3","ENST00000366812;ENST00000464927","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0006810(transport);GO:0005794(Golgi apparatus);GO:0006629(lipid metabolic process);GO:0005739(mitochondrion);GO:0006694(steroid biosynthetic process);GO:0005515(protein binding);GO:0000139(Golgi membrane);GO:0000062(fatty-acyl-CoA binding);GO:0034237(protein kinase A regulatory subunit binding);GO:0034237(protein kinase A regulatory subunit binding)","NA","NA","NA","acyl-CoA binding domain containing 3 [Source:HGNC Symbol;Acc:HGNC:15453]",{"v":3.81813902683063,"d":"3.82"},{"v":3.5565669960872,"d":"3.56"},{"v":1.07354621212849,"d":"1.07"},{"v":0.102384295131144,"d":"0.10"},{"v":0.803077415168819,"d":"0.80"},{"v":0.97922490784917,"d":"0.98"},"up","no"]
["ENSG00000196628","TCF4","ENST00000562680;ENST00000457482;ENST00000628689;ENST00000636400;ENST00000627320;ENST00000565908;ENST00000626595;ENST00000630720;ENST00000626631;ENST00000590810;ENST00000566279;ENST00000561831;ENST00000570287;ENST00000626466;ENST00000564403;ENST00000616053;ENST00000563686;ENST00000635822;ENST00000569012;ENST00000636822;ENST00000628636;ENST00000625849;ENST00000628078;ENST00000637923;ENST00000629343;ENST00000562030;ENST00000356073","GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0005634(nucleus);GO:0046983(protein dimerization activity);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0005515(protein binding);GO:0007399(nervous system development);GO:0030154(cell differentiation);GO:0045893(positive regulation of transcription, DNA-templated);GO:0042802(identical protein binding);GO:0005667(transcription factor complex);GO:0008022(protein C-terminus binding);GO:0046982(protein heterodimerization activity);GO:0000790(nuclear chromatin);GO:0070888(E-box binding);GO:0042803(protein homodimerization activity);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:0001077(transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0032993(protein-DNA complex);GO:0045666(positive regulation of neuron differentiation);GO:0001011(transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting);GO:0001087(transcription factor activity, TFIIB-class binding);GO:0001093(TFIIB-class transcription factor binding);GO:0043425(bHLH transcription factor binding);GO:0006352(DNA-templated transcription, initiation);GO:0006367(transcription initiation from RNA polymerase II promoter);GO:0065004(protein-DNA complex assembly);GO:0003682(chromatin binding);GO:0003714(transcription corepressor activity);GO:0043621(protein self-association);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0010629(negative regulation of gene expression);GO:0016525(negative regulation of angiogenesis);GO:0042118(endothelial cell activation);GO:1900746(regulation of vascular endothelial growth factor signaling pathway);GO:1900746(regulation of vascular endothelial growth factor signaling pathway)","NA","NA","NA","transcription factor 4 [Source:HGNC Symbol;Acc:HGNC:11634]",{"v":0.38718184781515,"d":"0.39"},{"v":0.289733921338221,"d":"0.29"},{"v":1.33633592513723,"d":"1.34"},{"v":0.418282714856084,"d":"0.42"},{"v":0.805373491876693,"d":"0.81"},{"v":0.98017457063076,"d":"0.98"},"up","no"]
["MSTRG.872","FMO5","ENST00000254090;ENST00000533174;ENST00000441068;ENST00000578284;ENST00000527849;ENST00000619062;ENST00000478432","GO:0004497(monooxygenase activity);GO:0004499(N,N-dimethylaniline monooxygenase activity);GO:0016491(oxidoreductase activity);GO:0050660(flavin adenine dinucleotide binding);GO:0050661(NADP binding);GO:0055114(oxidation-reduction process);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005783(endoplasmic reticulum);GO:0005829(cytosol);GO:0005789(endoplasmic reticulum membrane);GO:0008150(biological_process);GO:0043231(intracellular membrane-bounded organelle);GO:0031090(organelle membrane);GO:0031090(organelle membrane)","00982(Drug metabolism - cytochrome P450);00982(Drug metabolism - cytochrome P450)","K00485","EC:1.14.13.8","flavin containing monooxygenase 5 [Source:HGNC Symbol;Acc:HGNC:3773]",{"v":0.572821553123956,"d":"0.57"},{"v":0.422473047444036,"d":"0.42"},{"v":1.35587715379603,"d":"1.36"},{"v":0.439226472251721,"d":"0.44"},{"v":0.807196789687908,"d":"0.81"},{"v":0.980196614217472,"d":"0.98"},"up","no"]
["ENSG00000146707","POMZP3","ENST00000310842;ENST00000424818;ENST00000441393;ENST00000454397","GO:0005654(nucleoplasm);GO:0031965(nuclear membrane);GO:0003674(molecular_function);GO:0008150(biological_process);GO:0005575(cellular_component);GO:0031012(extracellular matrix);GO:0035803(egg coat formation);GO:0032190(acrosin binding);GO:0007339(binding of sperm to zona pellucida);GO:2000344(positive regulation of acrosome reaction);GO:2000344(positive regulation of acrosome reaction)","NA","NA","NA","POM121 and ZP3 fusion [Source:HGNC Symbol;Acc:HGNC:9203]",{"v":1.26232053734551,"d":"1.26"},{"v":0.935911716818914,"d":"0.94"},{"v":1.3487602672996,"d":"1.35"},{"v":0.431633942123555,"d":"0.43"},{"v":0.807687164644059,"d":"0.81"},{"v":0.980196614217472,"d":"0.98"},"up","no"]
["ENSG00000164180","TMEM161B","ENST00000296595;ENST00000510089;ENST00000506536;ENST00000514135;ENST00000511087;ENST00000515293;ENST00000507872;ENST00000515477;ENST00000503755;ENST00000503194","GO:0003676(nucleic acid binding);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0015074(DNA integration);GO:0015074(DNA integration)","NA","NA","NA","transmembrane protein 161B [Source:HGNC Symbol;Acc:HGNC:28483]",{"v":0.941708295582413,"d":"0.94"},{"v":0.872328761929569,"d":"0.87"},{"v":1.07953369954165,"d":"1.08"},{"v":0.110408280324528,"d":"0.11"},{"v":0.808526249836316,"d":"0.81"},{"v":0.980277181374549,"d":"0.98"},"up","no"]
["MSTRG.10127","SLC25A1","ENST00000215882;ENST00000468824;ENST00000461267;ENST00000470922;ENST00000451283","GO:0006810(transport);GO:0005634(nucleus);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0055085(transmembrane transport);GO:0005743(mitochondrial inner membrane);GO:0005739(mitochondrion);GO:0070062(extracellular exosome);GO:0006839(mitochondrial transport);GO:0006094(gluconeogenesis);GO:0046949(fatty-acyl-CoA biosynthetic process);GO:0015137(citrate transmembrane transporter activity);GO:0015142(tricarboxylic acid transmembrane transporter activity);GO:0006843(mitochondrial citrate transport);GO:0035674(tricarboxylic acid transmembrane transport);GO:0035674(tricarboxylic acid transmembrane transport)","NA","NA","NA","solute carrier family 25 member 1 [Source:HGNC Symbol;Acc:HGNC:10979]",{"v":6.37466119227099,"d":"6.37"},{"v":4.73443127003817,"d":"4.73"},{"v":1.34644708702669,"d":"1.35"},{"v":0.429157535607037,"d":"0.43"},{"v":0.810143105221989,"d":"0.81"},{"v":0.980554515309997,"d":"0.98"},"up","no"]
["ENSG00000159917","ZNF235","ENST00000291182;ENST00000589799;ENST00000587921;ENST00000591609;ENST00000589248;ENST00000592844","GO:0003676(nucleic acid binding);GO:0006355(regulation of transcription, DNA-templated);GO:0005622(intracellular);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0045892(negative regulation of transcription, DNA-templated);GO:0045892(negative regulation of transcription, DNA-templated)","NA","NA","NA","zinc finger protein 235 [Source:HGNC Symbol;Acc:HGNC:12866]",{"v":0.692200981632994,"d":"0.69"},{"v":0.643182704458173,"d":"0.64"},{"v":1.07621205737507,"d":"1.08"},{"v":0.105962375274383,"d":"0.11"},{"v":0.812325189673919,"d":"0.81"},{"v":0.980707108917046,"d":"0.98"},"up","no"]
["MSTRG.6984","ABI3","ENST00000225941;ENST00000571035;ENST00000419580;ENST00000573347","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005515(protein binding);GO:0042802(identical protein binding);GO:0030027(lamellipodium);GO:0006928(movement of cell or subcellular component);GO:0030334(regulation of cell migration);GO:0005622(intracellular);GO:0005622(intracellular)","NA","NA","NA","ABI family member 3 [Source:HGNC Symbol;Acc:HGNC:29859]",{"v":6.82317233021173,"d":"6.82"},{"v":6.31067601099349,"d":"6.31"},{"v":1.08121100153541,"d":"1.08"},{"v":0.112648096766805,"d":"0.11"},{"v":0.812506573586942,"d":"0.81"},{"v":0.980707108917046,"d":"0.98"},"up","no"]
["MSTRG.8994","PDCL3","ENST00000264254;ENST00000416255;ENST00000450127","GO:0005737(cytoplasm);GO:0005634(nucleus);GO:0005829(cytosol);GO:0006915(apoptotic process);GO:0005515(protein binding);GO:0016032(viral process);GO:0001525(angiogenesis);GO:0008479(queuine tRNA-ribosyltransferase activity);GO:0008616(queuosine biosynthetic process);GO:0045766(positive regulation of angiogenesis);GO:0001938(positive regulation of endothelial cell proliferation);GO:0006457(protein folding);GO:0044183(protein binding involved in protein folding);GO:0043184(vascular endothelial growth factor receptor 2 binding);GO:0050730(regulation of peptidyl-tyrosine phosphorylation);GO:2000059(negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process);GO:2000059(negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process)","NA","NA","NA","phosducin like 3 [Source:HGNC Symbol;Acc:HGNC:28860]",{"v":3.64279677880939,"d":"3.64"},{"v":2.70743230202075,"d":"2.71"},{"v":1.34548028258749,"d":"1.35"},{"v":0.428121249081881,"d":"0.43"},{"v":0.814247239492849,"d":"0.81"},{"v":0.981076149542775,"d":"0.98"},"up","no"]
["MSTRG.1830","ANXA11","ENST00000265447;ENST00000463657;ENST00000422982;ENST00000372231;ENST00000438331;ENST00000437799;ENST00000463340;ENST00000481805;ENST00000447489;ENST00000474545","GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0005509(calcium ion binding);GO:0051301(cell division);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0042470(melanosome);GO:0007049(cell cycle);GO:0005544(calcium-dependent phospholipid binding);GO:0005819(spindle);GO:0030496(midbody);GO:0070062(extracellular exosome);GO:0048306(calcium-dependent protein binding);GO:0032506(cytokinetic process);GO:0042581(specific granule);GO:0042582(azurophil granule);GO:0006909(phagocytosis);GO:0005635(nuclear envelope);GO:0044548(S100 protein binding);GO:0051592(response to calcium ion);GO:0045335(phagocytic vesicle);GO:0023026(MHC class II protein complex binding);GO:0008429(phosphatidylethanolamine binding);GO:0008429(phosphatidylethanolamine binding)","NA","NA","NA","annexin A11 [Source:HGNC Symbol;Acc:HGNC:535]",{"v":18.9479185436391,"d":"18.95"},{"v":14.1454742220134,"d":"14.15"},{"v":1.33950394636838,"d":"1.34"},{"v":0.421698831570513,"d":"0.42"},{"v":0.816184349285439,"d":"0.82"},{"v":0.981997074905328,"d":"0.98"},"up","no"]
["ENSG00000115761","NOL10","ENST00000345985;ENST00000381685;ENST00000538384;ENST00000431319","GO:0005634(nucleus);GO:0003723(RNA binding);GO:0005730(nucleolus);GO:0005730(nucleolus)","NA","NA","NA","nucleolar protein 10 [Source:HGNC Symbol;Acc:HGNC:25862]",{"v":2.38680899450837,"d":"2.39"},{"v":2.20890650915272,"d":"2.21"},{"v":1.08053871208152,"d":"1.08"},{"v":0.111750760052643,"d":"0.11"},{"v":0.816976996740628,"d":"0.82"},{"v":0.982250115244737,"d":"0.98"},"up","no"]
["MSTRG.2626","C11orf24","ENST00000304271;ENST00000529339;ENST00000532969;ENST00000529590;ENST00000527280;ENST00000531745;ENST00000530166;ENST00000533310;ENST00000532534","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005794(Golgi apparatus);GO:0005886(plasma membrane);GO:0005886(plasma membrane)","NA","NA","NA","chromosome 11 open reading frame 24 [Source:HGNC Symbol;Acc:HGNC:1174]",{"v":2.1385910642983,"d":"2.14"},{"v":1.97498536288902,"d":"1.97"},{"v":1.08283894376309,"d":"1.08"},{"v":0.114818679406879,"d":"0.11"},{"v":0.81949613014815,"d":"0.82"},{"v":0.982859290181213,"d":"0.98"},"up","no"]
["ENSG00000169224","GCSAML","ENST00000366488;ENST00000536561;ENST00000531662;ENST00000463359","GO:0050855(regulation of B cell receptor signaling pathway);GO:2000401(regulation of lymphocyte migration);GO:2000401(regulation of lymphocyte migration)","NA","NA","NA","germinal center associated signaling and motility like [Source:HGNC Symbol;Acc:HGNC:29583]",{"v":0.90936649017094,"d":"0.91"},{"v":0.679573102564103,"d":"0.68"},{"v":1.33814373573616,"d":"1.34"},{"v":0.420233090341314,"d":"0.42"},{"v":0.82007143954906,"d":"0.82"},{"v":0.982859290181213,"d":"0.98"},"up","no"]
["MSTRG.6014","LRRC29","ENST00000433915;ENST00000424285;ENST00000629962;ENST00000409037;ENST00000637247;ENST00000409509","GO:0005515(protein binding);GO:0005515(protein binding)","NA","NA","NA","leucine rich repeat containing 29 [Source:HGNC Symbol;Acc:HGNC:13605]",{"v":0.333686744567154,"d":"0.33"},{"v":0.326095105806911,"d":"0.33"},{"v":1.02328044372656,"d":"1.02"},{"v":0.033201589194848,"d":"0.03"},{"v":0.821482961705249,"d":"0.82"},{"v":0.983125245995053,"d":"0.98"},"up","no"]
["ENSG00000255363","AP001189.5","ENST00000637683;ENST00000532413","NA","NA","NA","NA",null,{"v":0.485426540869565,"d":"0.49"},{"v":0.458598365217391,"d":"0.46"},{"v":1.05850037350102,"d":"1.06"},{"v":0.0820217784130247,"d":"0.08"},{"v":0.82217803103468,"d":"0.82"},{"v":0.983125245995053,"d":"0.98"},"up","no"]
["MSTRG.3569","OSBPL8","ENST00000393250;MSTRG.3569.1;ENST00000611266;ENST00000553139;ENST00000548535;ENST00000550865;ENST00000547544;ENST00000552178;ENST00000393249;ENST00000548485;ENST00000551927;ENST00000546946;ENST00000548341;ENST00000547540;ENST00000549570;ENST00000552586;ENST00000550628","GO:0051897(positive regulation of protein kinase B signaling);GO:0032148(activation of protein kinase B activity);GO:0006810(transport);GO:0005634(nucleus);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0006869(lipid transport);GO:0008289(lipid binding);GO:0005829(cytosol);GO:0031965(nuclear membrane);GO:0001786(phosphatidylserine binding);GO:0005548(phospholipid transporter activity);GO:0036150(phosphatidylserine acyl-chain remodeling);GO:0045444(fat cell differentiation);GO:0015914(phospholipid transport);GO:0070273(phosphatidylinositol-4-phosphate binding);GO:0015485(cholesterol binding);GO:2001275(positive regulation of glucose import in response to insulin stimulus);GO:0010891(negative regulation of sequestering of triglyceride);GO:0030336(negative regulation of cell migration);GO:0046628(positive regulation of insulin receptor signaling pathway);GO:0090204(protein localization to nuclear pore);GO:0090204(protein localization to nuclear pore)","NA","NA","NA","oxysterol binding protein like 8 [Source:HGNC Symbol;Acc:HGNC:16396]",{"v":18.3432484621657,"d":"18.34"},{"v":13.7546328885627,"d":"13.75"},{"v":1.3336050922463,"d":"1.33"},{"v":0.415331518243553,"d":"0.42"},{"v":0.823454407401135,"d":"0.82"},{"v":0.983146609292128,"d":"0.98"},"up","no"]
["MSTRG.12433","LARS","ENST00000394434;ENST00000507095;ENST00000274562;ENST00000504323;ENST00000506436;ENST00000618084;ENST00000504611;ENST00000506231;ENST00000511505;ENST00000508709;ENST00000508667;ENST00000514104;ENST00000503654","GO:0005737(cytoplasm);GO:0006412(translation);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0005829(cytosol);GO:0016874(ligase activity);GO:0005515(protein binding);GO:0016604(nuclear body);GO:0004812(aminoacyl-tRNA ligase activity);GO:0006418(tRNA aminoacylation for protein translation);GO:0002161(aminoacyl-tRNA editing activity);GO:0006450(regulation of translational fidelity);GO:0004823(leucine-tRNA ligase activity);GO:0006429(leucyl-tRNA aminoacylation);GO:0017101(aminoacyl-tRNA synthetase multienzyme complex);GO:0005783(endoplasmic reticulum);GO:0034198(cellular response to amino acid starvation);GO:0006438(valyl-tRNA aminoacylation);GO:0008361(regulation of cell size);GO:0010507(negative regulation of autophagy);GO:0071230(cellular response to amino acid stimulus);GO:0071233(cellular response to leucine);GO:1990253(cellular response to leucine starvation);GO:0005764(lysosome);GO:0012505(endomembrane system);GO:0004819(glutamine-tRNA ligase activity);GO:0006425(glutaminyl-tRNA aminoacylation);GO:0004832(valine-tRNA ligase activity);GO:1904263(positive regulation of TORC1 signaling);GO:0005096(GTPase activator activity);GO:0006622(protein targeting to lysosome);GO:0043547(positive regulation of GTPase activity);GO:0043547(positive regulation of GTPase activity)","00970(Aminoacyl-tRNA biosynthesis);00970(Aminoacyl-tRNA biosynthesis)","K01869","EC:6.1.1.4","leucyl-tRNA synthetase [Source:HGNC Symbol;Acc:HGNC:6512]",{"v":5.05081404927322,"d":"5.05"},{"v":3.79098080623306,"d":"3.79"},{"v":1.33232382526674,"d":"1.33"},{"v":0.413944776348335,"d":"0.41"},{"v":0.82453297597017,"d":"0.82"},{"v":0.983478526095786,"d":"0.98"},"up","no"]
["MSTRG.7359","OGFOD3","ENST00000329197;ENST00000313056;ENST00000580445;ENST00000577495;ENST00000583445;ENST00000579407;ENST00000583897;ENST00000577606;ENST00000578586","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0046872(metal ion binding);GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0005506(iron ion binding);GO:0016705(oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen);GO:0031418(L-ascorbic acid binding);GO:0051213(dioxygenase activity);GO:0070062(extracellular exosome);GO:0070062(extracellular exosome)","NA","NA","NA","2-oxoglutarate and iron dependent oxygenase domain containing 3 [Source:HGNC Symbol;Acc:HGNC:26174]",{"v":1.29227508324206,"d":"1.29"},{"v":0.966874562353309,"d":"0.97"},{"v":1.33654884879456,"d":"1.34"},{"v":0.418512566818398,"d":"0.42"},{"v":0.825875742775058,"d":"0.83"},{"v":0.983664409314002,"d":"0.98"},"up","no"]
["MSTRG.15503","RENBP","ENST00000393700;ENST00000471056;ENST00000462086;ENST00000457282;ENST00000369997;ENST00000475904;ENST00000442361;ENST00000423624;ENST00000464227","GO:0016853(isomerase activity);GO:0003824(catalytic activity);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0004866(endopeptidase inhibitor activity);GO:0006048(UDP-N-acetylglucosamine biosynthetic process);GO:0008217(regulation of blood pressure);GO:0004857(enzyme inhibitor activity);GO:0005524(ATP binding);GO:0017076(purine nucleotide binding);GO:0042803(protein homodimerization activity);GO:0050121(N-acylglucosamine 2-epimerase activity);GO:0006044(N-acetylglucosamine metabolic process);GO:0006051(N-acetylmannosamine metabolic process);GO:0010951(negative regulation of endopeptidase activity);GO:0019262(N-acetylneuraminate catabolic process);GO:0043086(negative regulation of catalytic activity);GO:0043086(negative regulation of catalytic activity)","00520(Amino sugar and nucleotide sugar metabolism);00520(Amino sugar and nucleotide sugar metabolism)","K01787","EC:5.1.3.8","renin binding protein [Source:HGNC Symbol;Acc:HGNC:9959]",{"v":6.6842711560525,"d":"6.68"},{"v":6.12680525085075,"d":"6.13"},{"v":1.09098802432546,"d":"1.09"},{"v":0.125635265418533,"d":"0.13"},{"v":0.828071426902592,"d":"0.83"},{"v":0.983911547706084,"d":"0.98"},"up","no"]
["MSTRG.290","NUDC","ENST00000321265;ENST00000435827;ENST00000484772","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005737(cytoplasm);GO:0005634(nucleus);GO:0051301(cell division);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0007049(cell cycle);GO:0005874(microtubule);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0045296(cadherin binding);GO:0007062(sister chromatid cohesion);GO:0007275(multicellular organism development);GO:0008283(cell proliferation);GO:0006457(protein folding);GO:0051082(unfolded protein binding);GO:0051082(unfolded protein binding)","NA","NA","NA","nuclear distribution C, dynein complex regulator [Source:HGNC Symbol;Acc:HGNC:8045]",{"v":9.85237644047619,"d":"9.85"},{"v":9.02041690826331,"d":"9.02"},{"v":1.09223071845501,"d":"1.09"},{"v":0.127277637588158,"d":"0.13"},{"v":0.829368495293121,"d":"0.83"},{"v":0.983911547706084,"d":"0.98"},"up","no"]
["MSTRG.1842","FAM35A","ENST00000298784;ENST00000298786;ENST00000437629","NA","NA","NA","NA","family with sequence similarity 35 member A [Source:HGNC Symbol;Acc:HGNC:28773]",{"v":5.20691798491278,"d":"5.21"},{"v":4.76475297006129,"d":"4.76"},{"v":1.09279914774801,"d":"1.09"},{"v":0.128028263612348,"d":"0.13"},{"v":0.830206577881936,"d":"0.83"},{"v":0.983911547706084,"d":"0.98"},"up","no"]
["ENSG00000261455","LINC01003","ENST00000564834","NA","NA","NA","NA","long intergenic non-protein coding RNA 1003 [Source:HGNC Symbol;Acc:HGNC:48957]",{"v":2.641691,"d":"2.64"},{"v":2.422369,"d":"2.42"},{"v":1.09054029340699,"d":"1.09"},{"v":0.125043075824162,"d":"0.13"},{"v":0.830740620913484,"d":"0.83"},{"v":0.983911547706084,"d":"0.98"},"up","no"]
["MSTRG.13525","NFE2L3","ENST00000056233;ENST00000606261;ENST00000607375","GO:0005634(nucleus);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0003713(transcription coactivator activity);GO:0006366(transcription from RNA polymerase II promoter);GO:0045893(positive regulation of transcription, DNA-templated);GO:0000976(transcription regulatory region sequence-specific DNA binding);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:0001078(transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0000122(negative regulation of transcription from RNA polymerase II promoter)","NA","NA","NA","nuclear factor, erythroid 2 like 3 [Source:HGNC Symbol;Acc:HGNC:7783]",{"v":0.406577147564133,"d":"0.41"},{"v":0.377315500117675,"d":"0.38"},{"v":1.07755220084341,"d":"1.08"},{"v":0.10775776079812,"d":"0.11"},{"v":0.832616907268909,"d":"0.83"},{"v":0.983911547706084,"d":"0.98"},"up","no"]
["MSTRG.7157","PRKAR1A;ARSG;AC007780.1","ENST00000392711;ENST00000589228;ENST00000621439;ENST00000585815;ENST00000589017;ENST00000578726;ENST00000581032;ENST00000585427;ENST00000448504;ENST00000588178;ENST00000585907;ENST00000585460;ENST00000592030;ENST00000536854;ENST00000578554;ENST00000358598;ENST00000590353;ENST00000588702;ENST00000586515;ENST00000590690;ENST00000585981;ENST00000586541;ENST00000582154;ENST00000591567;MSTRG.7157.10;ENST00000592194;ENST00000392710;ENST00000585608;ENST00000592800;ENST00000586397;ENST00000588188","GO:2000480(negative regulation of cAMP-dependent protein kinase activity);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0000166(nucleotide binding);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0008603(cAMP-dependent protein kinase regulator activity);GO:0030552(cAMP binding);GO:0001932(regulation of protein phosphorylation);GO:0005952(cAMP-dependent protein kinase complex);GO:0005829(cytosol);GO:0031625(ubiquitin protein ligase binding);GO:0046007(negative regulation of activated T cell proliferation);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0035556(intracellular signal transduction);GO:0007596(blood coagulation);GO:0001772(immunological synapse);GO:0034236(protein kinase A catalytic subunit binding);GO:0003091(renal water homeostasis);GO:0034199(activation of protein kinase A activity);GO:0071377(cellular response to glucagon stimulus);GO:0044853(plasma membrane raft);GO:0097546(ciliary base);GO:0004862(cAMP-dependent protein kinase inhibitor activity);GO:0031588(nucleotide-activated protein kinase complex);GO:0043234(protein complex);GO:0045859(regulation of protein kinase activity);GO:0001707(mesoderm formation);GO:0006469(negative regulation of protein kinase activity);GO:0007143(female meiotic nuclear division);GO:0007507(heart development);GO:0045214(sarcomere organization);GO:0045835(negative regulation of meiotic nuclear division);GO:0060038(cardiac muscle cell proliferation);GO:0031594(neuromuscular junction);GO:0046872(metal ion binding);GO:0016787(hydrolase activity);GO:0003824(catalytic activity);GO:0008152(metabolic process);GO:0005615(extracellular space);GO:0008484(sulfuric ester hydrolase activity);GO:0005764(lysosome);GO:0006687(glycosphingolipid metabolic process);GO:0043687(post-translational protein modification);GO:0005788(endoplasmic reticulum lumen);GO:0005783(endoplasmic reticulum);GO:0006790(sulfur compound metabolic process);GO:0004065(arylsulfatase activity);GO:0031594(neuromuscular junction)","04910(Insulin signaling pathway);04142(Lysosome);04910(Insulin signaling pathway)","K04739;K12381","EC:3.1.6.-","protein kinase cAMP-dependent type I regulatory subunit alpha [Source:HGNC Symbol;Acc:HGNC:9388];arylsulfatase G [Source:HGNC Symbol;Acc:HGNC:24102]",{"v":13.1820976301464,"d":"13.18"},{"v":12.0299272468914,"d":"12.03"},{"v":1.09577534091511,"d":"1.10"},{"v":0.131952043033066,"d":"0.13"},{"v":0.833527812329744,"d":"0.83"},{"v":0.983911547706084,"d":"0.98"},"up","no"]
["ENSG00000123352","SPATS2","ENST00000549412;ENST00000549298;ENST00000548377;ENST00000549045;ENST00000553127;ENST00000547003;ENST00000547865;ENST00000321898;ENST00000552918;ENST00000548777","GO:0003723(RNA binding);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005829(cytosol)","NA","NA","NA","spermatogenesis associated serine rich 2 [Source:HGNC Symbol;Acc:HGNC:18650]",{"v":0.532301034064327,"d":"0.53"},{"v":0.402802572807017,"d":"0.40"},{"v":1.32149362988144,"d":"1.32"},{"v":0.402169470639256,"d":"0.40"},{"v":0.834271029651408,"d":"0.83"},{"v":0.983911547706084,"d":"0.98"},"up","no"]
["MSTRG.6959","NFE2L1","ENST00000585291;ENST00000361665;ENST00000357480;ENST00000362042;ENST00000583060;ENST00000583378;ENST00000536222;ENST00000579481;ENST00000581441;ENST00000583210;ENST00000582155;ENST00000580037;ENST00000577431;ENST00000581319;ENST00000582574;ENST00000584634;ENST00000577411","GO:0005634(nucleus);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005829(cytosol);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005515(protein binding);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0005737(cytoplasm);GO:0034599(cellular response to oxidative stress);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0006954(inflammatory response);GO:0006366(transcription from RNA polymerase II promoter);GO:0045893(positive regulation of transcription, DNA-templated);GO:0009653(anatomical structure morphogenesis);GO:0000976(transcription regulatory region sequence-specific DNA binding);GO:0003712(transcription cofactor activity);GO:0006783(heme biosynthetic process);GO:0000980(RNA polymerase II distal enhancer sequence-specific DNA binding);GO:0001190(transcriptional activator activity, RNA polymerase II transcription factor binding);GO:0001205(transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding);GO:0019904(protein domain specific binding);GO:0032403(protein complex binding);GO:0030218(erythrocyte differentiation);GO:0043234(protein complex);GO:0043234(protein complex)","NA","NA","NA","nuclear factor, erythroid 2 like 1 [Source:HGNC Symbol;Acc:HGNC:7781]",{"v":8.35182619811159,"d":"8.35"},{"v":6.30668397819742,"d":"6.31"},{"v":1.32428170287022,"d":"1.32"},{"v":0.405210046695459,"d":"0.41"},{"v":0.835730218995492,"d":"0.84"},{"v":0.984015532621951,"d":"0.98"},"up","no"]
["ENSG00000163704","PRRT3","ENST00000411976;ENST00000295984;ENST00000412055","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016021(integral component of membrane)","NA","NA","NA","proline rich transmembrane protein 3 [Source:HGNC Symbol;Acc:HGNC:26591]",{"v":0.467327404163493,"d":"0.47"},{"v":0.346926792079208,"d":"0.35"},{"v":1.34704904560036,"d":"1.35"},{"v":0.429802379795221,"d":"0.43"},{"v":0.836411044876556,"d":"0.84"},{"v":0.984015532621951,"d":"0.98"},"up","no"]
["ENSG00000154144","TBRG1","ENST00000284290;ENST00000491010;ENST00000441174;ENST00000531667;ENST00000529543;ENST00000531033;ENST00000452080;ENST00000473629;ENST00000438907","GO:0005634(nucleus);GO:0007049(cell cycle);GO:0005515(protein binding);GO:0007050(cell cycle arrest);GO:0008285(negative regulation of cell proliferation);GO:0006260(DNA replication);GO:0032066(nucleolus to nucleoplasm transport);GO:0050821(protein stabilization);GO:0050821(protein stabilization)","NA","NA","NA","transforming growth factor beta regulator 1 [Source:HGNC Symbol;Acc:HGNC:29551]",{"v":3.49359812962125,"d":"3.49"},{"v":3.17634277229516,"d":"3.18"},{"v":1.09988070560056,"d":"1.10"},{"v":0.137347055775828,"d":"0.14"},{"v":0.837653262915187,"d":"0.84"},{"v":0.98404165141933,"d":"0.98"},"up","no"]
["MSTRG.5370","HOMER2","ENST00000450735;ENST00000558552;ENST00000304231;ENST00000500334;ENST00000560374;ENST00000619240;ENST00000558090","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0042995(cell projection);GO:0005515(protein binding);GO:0030054(cell junction);GO:0045202(synapse);GO:0045211(postsynaptic membrane);GO:0032420(stereocilium);GO:0014069(postsynaptic density);GO:0007605(sensory perception of sound);GO:0032426(stereocilium tip);GO:0007216(G-protein coupled glutamate receptor signaling pathway);GO:0035256(G-protein coupled glutamate receptor binding);GO:0003779(actin binding);GO:0019904(protein domain specific binding);GO:0030160(GKAP/Homer scaffold activity);GO:0035254(glutamate receptor binding);GO:0042803(protein homodimerization activity);GO:0046982(protein heterodimerization activity);GO:0008277(regulation of G-protein coupled receptor protein signaling pathway);GO:0035584(calcium-mediated signaling using intracellular calcium source);GO:0048148(behavioral response to cocaine);GO:0048875(chemical homeostasis within a tissue);GO:0030425(dendrite);GO:0043025(neuronal cell body);GO:0045177(apical part of cell);GO:0045177(apical part of cell)","04068(FoxO signaling pathway);04724(Glutamatergic synapse);04724(Glutamatergic synapse)","K15010","NA","homer scaffolding protein 2 [Source:HGNC Symbol;Acc:HGNC:17513]",{"v":0.354615004494382,"d":"0.35"},{"v":0.323364981477698,"d":"0.32"},{"v":1.09664009650606,"d":"1.10"},{"v":0.133090129041806,"d":"0.13"},{"v":0.83939465657871,"d":"0.84"},{"v":0.98404165141933,"d":"0.98"},"up","no"]
["MSTRG.3080","PTPN6","ENST00000456013;ENST00000539029;ENST00000399448;ENST00000416215;MSTRG.3080.7;ENST00000535462;ENST00000318974;ENST00000538318;ENST00000543744;ENST00000542277;ENST00000542848;ENST00000540740;ENST00000537533;ENST00000536521;ENST00000542761;ENST00000545153;ENST00000542462;ENST00000543115;ENST00000536013;ENST00000534900;ENST00000539365;ENST00000541698","GO:0008284(positive regulation of cell proliferation);GO:0005737(cytoplasm);GO:0005634(nucleus);GO:0014068(positive regulation of phosphatidylinositol 3-kinase signaling);GO:0005730(nucleolus);GO:0016787(hydrolase activity);GO:0004725(protein tyrosine phosphatase activity);GO:0016791(phosphatase activity);GO:0006470(protein dephosphorylation);GO:0016311(dephosphorylation);GO:0035335(peptidyl-tyrosine dephosphorylation);GO:0004721(phosphoprotein phosphatase activity);GO:0005515(protein binding);GO:0030154(cell differentiation);GO:0050900(leukocyte migration);GO:0005576(extracellular region);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0019901(protein kinase binding);GO:0008285(negative regulation of cell proliferation);GO:0008283(cell proliferation);GO:0043234(protein complex);GO:0043312(neutrophil degranulation);GO:0007186(G-protein coupled receptor signaling pathway);GO:0006915(apoptotic process);GO:0030168(platelet activation);GO:0016020(membrane);GO:0035580(specific granule lumen);GO:1904724(tertiary granule lumen);GO:0031295(T cell costimulation);GO:0070372(regulation of ERK1 and ERK2 cascade);GO:0018108(peptidyl-tyrosine phosphorylation);GO:0060338(regulation of type I interferon-mediated signaling pathway);GO:0050732(negative regulation of peptidyl-tyrosine phosphorylation);GO:0005001(transmembrane receptor protein tyrosine phosphatase activity);GO:2000045(regulation of G1/S transition of mitotic cell cycle);GO:0001784(phosphotyrosine residue binding);GO:0017124(SH3 domain binding);GO:0042169(SH2 domain binding);GO:0050839(cell adhesion molecule binding);GO:0002244(hematopoietic progenitor cell differentiation);GO:0002924(negative regulation of humoral immune response mediated by circulating immunoglobulin);GO:0030220(platelet formation);GO:0033277(abortive mitotic cell cycle);GO:0033630(positive regulation of cell adhesion mediated by integrin);GO:0035556(intracellular signal transduction);GO:0035855(megakaryocyte development);GO:0042130(negative regulation of T cell proliferation);GO:0042267(natural killer cell mediated cytotoxicity);GO:0043407(negative regulation of MAP kinase activity);GO:0043409(negative regulation of MAPK cascade);GO:0045577(regulation of B cell differentiation);GO:0050853(B cell receptor signaling pathway);GO:0050859(negative regulation of B cell receptor signaling pathway);GO:0050860(negative regulation of T cell receptor signaling pathway);GO:0051279(regulation of release of sequestered calcium ion into cytosol);GO:0070527(platelet aggregation);GO:0005911(cell-cell junction);GO:0042105(alpha-beta T cell receptor complex);GO:0042105(alpha-beta T cell receptor complex)","04630(Jak-STAT signaling pathway);04520(Adherens junction);04650(Natural killer cell mediated cytotoxicity);04660(T cell receptor signaling pathway);04662(B cell receptor signaling pathway);05205(Proteoglycans in cancer);05140(Leishmaniasis);05140(Leishmaniasis)","K05697","EC:3.1.3.48","protein tyrosine phosphatase, non-receptor type 6 [Source:HGNC Symbol;Acc:HGNC:9658]",{"v":63.4477053581553,"d":"63.45"},{"v":57.6816257538431,"d":"57.68"},{"v":1.09996388848191,"d":"1.10"},{"v":0.137456161237895,"d":"0.14"},{"v":0.84009015401101,"d":"0.84"},{"v":0.984258167729001,"d":"0.98"},"up","no"]
["MSTRG.2781","CCDC90B","ENST00000529611;ENST00000525503;ENST00000529689;ENST00000527025;ENST00000526631;ENST00000528149;ENST00000525916;ENST00000529073;ENST00000530253;ENST00000529312;ENST00000529745;ENST00000529856;ENST00000526265;ENST00000260054;ENST00000455220;ENST00000533761;ENST00000534753;ENST00000527495","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005739(mitochondrion);GO:0031966(mitochondrial membrane);GO:0005515(protein binding);GO:0005515(protein binding)","NA","NA","NA","coiled-coil domain containing 90B [Source:HGNC Symbol;Acc:HGNC:28108]",{"v":1.70705285490017,"d":"1.71"},{"v":1.54844209769852,"d":"1.55"},{"v":1.10243247547803,"d":"1.10"},{"v":0.140690292720343,"d":"0.14"},{"v":0.841461676864709,"d":"0.84"},{"v":0.984276234229439,"d":"0.98"},"up","no"]
["MSTRG.2431","TMEM109","ENST00000536171;ENST00000227525;ENST00000540280","GO:0006810(transport);GO:0005634(nucleus);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005244(voltage-gated ion channel activity);GO:0006811(ion transport);GO:0034765(regulation of ion transmembrane transport);GO:0003674(molecular_function);GO:0070062(extracellular exosome);GO:0016529(sarcoplasmic reticulum);GO:0033017(sarcoplasmic reticulum membrane);GO:0060548(negative regulation of cell death);GO:0071480(cellular response to gamma radiation);GO:0005640(nuclear outer membrane);GO:0042771(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator);GO:0042771(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)","NA","NA","NA","transmembrane protein 109 [Source:HGNC Symbol;Acc:HGNC:28771]",{"v":19.0971629491945,"d":"19.10"},{"v":14.4841620136307,"d":"14.48"},{"v":1.3184858696846,"d":"1.32"},{"v":0.398882109810594,"d":"0.40"},{"v":0.843820975049893,"d":"0.84"},{"v":0.9846443013834,"d":"0.98"},"up","no"]
["MSTRG.12077","SREK1IP1","ENST00000513458;ENST00000495198;ENST00000510616;ENST00000506252","GO:0003676(nucleic acid binding);GO:0006397(mRNA processing);GO:0008380(RNA splicing);GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0005515(protein binding);GO:0005515(protein binding)","NA","NA","NA","SREK1 interacting protein 1 [Source:HGNC Symbol;Acc:HGNC:26716]",{"v":2.73450924810933,"d":"2.73"},{"v":2.07313666578214,"d":"2.07"},{"v":1.31902025237573,"d":"1.32"},{"v":0.399466716050957,"d":"0.40"},{"v":0.844756209332812,"d":"0.84"},{"v":0.9846443013834,"d":"0.98"},"up","no"]
["MSTRG.5467","DDX11L9","ENST00000559159;ENST00000562189","NA","NA","NA","NA","DEAD/H-box helicase 11 like 9 [Source:HGNC Symbol;Acc:HGNC:37109]",{"v":3.31612173793103,"d":"3.32"},{"v":3.01650133333333,"d":"3.02"},{"v":1.09932712486708,"d":"1.10"},{"v":0.13662075043557,"d":"0.14"},{"v":0.846073415191658,"d":"0.85"},{"v":0.9846443013834,"d":"0.98"},"up","no"]
["MSTRG.3254","C2CD5","ENST00000333957;ENST00000535304;ENST00000396028;ENST00000541310;ENST00000542768;ENST00000543888;ENST00000545552;ENST00000539615;ENST00000542676;ENST00000543797;ENST00000536386;ENST00000446597;ENST00000540703;ENST00000540245","GO:0006810(transport);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0015031(protein transport);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0042995(cell projection);GO:0005815(microtubule organizing center);GO:0030659(cytoplasmic vesicle membrane);GO:0031410(cytoplasmic vesicle);GO:0005544(calcium-dependent phospholipid binding);GO:0005509(calcium ion binding);GO:0008289(lipid binding);GO:0005938(cell cortex);GO:0032587(ruffle membrane);GO:0090314(positive regulation of protein targeting to membrane);GO:0001726(ruffle);GO:0032869(cellular response to insulin stimulus);GO:0010828(positive regulation of glucose transport);GO:0031340(positive regulation of vesicle fusion);GO:0038028(insulin receptor signaling pathway via phosphatidylinositol 3-kinase);GO:0065002(intracellular protein transmembrane transport);GO:0006906(vesicle fusion);GO:0072659(protein localization to plasma membrane);GO:2001275(positive regulation of glucose import in response to insulin stimulus);GO:2001275(positive regulation of glucose import in response to insulin stimulus)","NA","NA","NA","C2 calcium dependent domain containing 5 [Source:HGNC Symbol;Acc:HGNC:29062]",{"v":4.69063543098091,"d":"4.69"},{"v":3.55825166178429,"d":"3.56"},{"v":1.31824161887099,"d":"1.32"},{"v":0.398614824366751,"d":"0.40"},{"v":0.846470803708701,"d":"0.85"},{"v":0.9846443013834,"d":"0.98"},"up","no"]
["ENSG00000088970","KIZ","ENST00000616679;ENST00000619189;ENST00000620891;ENST00000616848;ENST00000441136;ENST00000620553;ENST00000612654;ENST00000621366;ENST00000619574","GO:0005737(cytoplasm);GO:0005856(cytoskeleton);GO:0042995(cell projection);GO:0005515(protein binding);GO:0005813(centrosome);GO:0005815(microtubule organizing center);GO:0007051(spindle organization);GO:0019901(protein kinase binding);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016021(integral component of membrane)","NA","NA","NA","kizuna centrosomal protein [Source:HGNC Symbol;Acc:HGNC:15865]",{"v":2.55443773746879,"d":"2.55"},{"v":1.93732722181679,"d":"1.94"},{"v":1.31853705904844,"d":"1.32"},{"v":0.398938120428143,"d":"0.40"},{"v":0.847232304829265,"d":"0.85"},{"v":0.9846443013834,"d":"0.98"},"up","no"]
["MSTRG.14255","TRIM35","ENST00000305364;ENST00000519219;ENST00000521283;ENST00000521253","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0005622(intracellular);GO:0006915(apoptotic process);GO:0045087(innate immune response);GO:0003674(molecular_function);GO:0043065(positive regulation of apoptotic process);GO:0045930(negative regulation of mitotic cell cycle);GO:1902187(negative regulation of viral release from host cell);GO:1902187(negative regulation of viral release from host cell)","NA","NA","NA","tripartite motif containing 35 [Source:HGNC Symbol;Acc:HGNC:16285]",{"v":4.23502428250176,"d":"4.24"},{"v":3.83623698032326,"d":"3.84"},{"v":1.10395272873494,"d":"1.10"},{"v":0.142678397224983,"d":"0.14"},{"v":0.848444567023336,"d":"0.85"},{"v":0.9846443013834,"d":"0.98"},"up","no"]
["MSTRG.13840","PLOD3","ENST00000223127;ENST00000489927;ENST00000466881;ENST00000478082;ENST00000463479;ENST00000440925;ENST00000456079;ENST00000460132;ENST00000421736;ENST00000424135;ENST00000487563;ENST00000460475;ENST00000478264","GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0005783(endoplasmic reticulum);GO:0005506(iron ion binding);GO:0016705(oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen);GO:0031418(L-ascorbic acid binding);GO:0008475(procollagen-lysine 5-dioxygenase activity);GO:0016020(membrane);GO:0046872(metal ion binding);GO:0005515(protein binding);GO:0051213(dioxygenase activity);GO:0005789(endoplasmic reticulum membrane);GO:0070062(extracellular exosome);GO:0005794(Golgi apparatus);GO:0017185(peptidyl-lysine hydroxylation);GO:0046947(hydroxylysine biosynthetic process);GO:0030867(rough endoplasmic reticulum membrane);GO:0033823(procollagen glucosyltransferase activity);GO:0050211(procollagen galactosyltransferase activity);GO:0001701(in utero embryonic development);GO:0001886(endothelial cell morphogenesis);GO:0006493(protein O-linked glycosylation);GO:0008104(protein localization);GO:0021915(neural tube development);GO:0030199(collagen fibril organization);GO:0032870(cellular response to hormone stimulus);GO:0032963(collagen metabolic process);GO:0042311(vasodilation);GO:0048730(epidermis morphogenesis);GO:0060425(lung morphogenesis);GO:0070831(basement membrane assembly);GO:0005802(trans-Golgi network);GO:0031012(extracellular matrix);GO:0031012(extracellular matrix)","00310(Lysine degradation);00514(Other types of O-glycan biosynthesis);00514(Other types of O-glycan biosynthesis)","K13646","EC:1.14.11.4;EC:2.4.1.50","procollagen-lysine,2-oxoglutarate 5-dioxygenase 3 [Source:HGNC Symbol;Acc:HGNC:9083]",{"v":2.8321807607124,"d":"2.83"},{"v":2.15319984429554,"d":"2.15"},{"v":1.31533576329001,"d":"1.32"},{"v":0.395431120583503,"d":"0.40"},{"v":0.850156505090545,"d":"0.85"},{"v":0.9846443013834,"d":"0.98"},"up","no"]
["ENSG00000121964","GTDC1","ENST00000491448;ENST00000392867;ENST00000484303;ENST00000542155;ENST00000415569;ENST00000417450;ENST00000482601;ENST00000241391;ENST00000437114;ENST00000467352;ENST00000429978;ENST00000409298;ENST00000344850;ENST00000392871;ENST00000409214;ENST00000618778","GO:0016740(transferase activity);GO:0016757(transferase activity, transferring glycosyl groups);GO:0016757(transferase activity, transferring glycosyl groups)","NA","NA","NA","glycosyltransferase like domain containing 1 [Source:HGNC Symbol;Acc:HGNC:20887]",{"v":0.856553605493574,"d":"0.86"},{"v":0.654166084945629,"d":"0.65"},{"v":1.3093824721359,"d":"1.31"},{"v":0.388886571734304,"d":"0.39"},{"v":0.850454620398591,"d":"0.85"},{"v":0.9846443013834,"d":"0.98"},"up","no"]
["ENSG00000152455","SUV39H2","ENST00000378331;ENST00000313519;ENST00000354919;ENST00000378325;ENST00000420416;ENST00000433779","GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0018024(histone-lysine N-methyltransferase activity);GO:0034968(histone lysine methylation);GO:0008270(zinc ion binding);GO:0008168(methyltransferase activity);GO:0016740(transferase activity);GO:0032259(methylation);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0016569(covalent chromatin modification);GO:0005694(chromosome);GO:0005515(protein binding);GO:0007049(cell cycle);GO:0048511(rhythmic process);GO:0030154(cell differentiation);GO:0000775(chromosome, centromeric region);GO:0005654(nucleoplasm);GO:0045892(negative regulation of transcription, DNA-templated);GO:0000785(chromatin);GO:0006338(chromatin remodeling);GO:0000976(transcription regulatory region sequence-specific DNA binding);GO:0042754(negative regulation of circadian rhythm);GO:0046974(histone methyltransferase activity (H3-K9 specific));GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0036123(histone H3-K9 dimethylation);GO:0036124(histone H3-K9 trimethylation);GO:0071456(cellular response to hypoxia);GO:1904047(S-adenosyl-L-methionine binding);GO:0006333(chromatin assembly or disassembly);GO:0006333(chromatin assembly or disassembly)","00310(Lysine degradation);00310(Lysine degradation)","K11419","EC:2.1.1.43","suppressor of variegation 3-9 homolog 2 [Source:HGNC Symbol;Acc:HGNC:17287]",{"v":0.645085792426367,"d":"0.65"},{"v":0.588804686676017,"d":"0.59"},{"v":1.09558535627166,"d":"1.10"},{"v":0.131701888045811,"d":"0.13"},{"v":0.852251349536119,"d":"0.85"},{"v":0.984976416228804,"d":"0.98"},"up","no"]
["MSTRG.2367","SPI1","ENST00000533968;ENST00000227163;ENST00000378538;ENST00000533030","GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0006355(regulation of transcription, DNA-templated);GO:0006366(transcription from RNA polymerase II promoter);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0043565(sequence-specific DNA binding);GO:0005515(protein binding);GO:0001047(core promoter binding);GO:1902036(regulation of hematopoietic stem cell differentiation);GO:0000981(RNA polymerase II transcription factor activity, sequence-specific DNA binding);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0045893(positive regulation of transcription, DNA-templated);GO:0045892(negative regulation of transcription, DNA-templated);GO:0000790(nuclear chromatin);GO:0001085(RNA polymerase II transcription factor binding);GO:0000980(RNA polymerase II distal enhancer sequence-specific DNA binding);GO:0003705(transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding);GO:1902895(positive regulation of pri-miRNA transcription from RNA polymerase II promoter);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0043966(histone H3 acetylation);GO:0045814(negative regulation of gene expression, epigenetic);GO:0051525(NFAT protein binding);GO:0044027(hypermethylation of CpG island);GO:0045646(regulation of erythrocyte differentiation);GO:0090241(negative regulation of histone H4 acetylation);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:0000979(RNA polymerase II core promoter sequence-specific DNA binding);GO:0000982(transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0001077(transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0001078(transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0001205(transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding);GO:0001944(vasculature development);GO:0002320(lymphoid progenitor cell differentiation);GO:0002573(myeloid leukocyte differentiation);GO:0030098(lymphocyte differentiation);GO:0030218(erythrocyte differentiation);GO:0030225(macrophage differentiation);GO:0030851(granulocyte differentiation);GO:0035019(somatic stem cell population maintenance);GO:0043011(myeloid dendritic cell differentiation);GO:0045347(negative regulation of MHC class II biosynthetic process);GO:0060033(anatomical structure regression);GO:0071361(cellular response to ethanol);GO:1902262(apoptotic process involved in blood vessel morphogenesis);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016021(integral component of membrane)","04380(Osteoclast differentiation);05200(Pathways in cancer);05202(Transcriptional misregulation in cancers);05221(Acute myeloid leukemia);05166(HTLV-I infection);05169(Epstein-Barr virus infection);05169(Epstein-Barr virus infection)","K09438","NA","Spi-1 proto-oncogene [Source:HGNC Symbol;Acc:HGNC:11241]",{"v":117.264691436443,"d":"117.26"},{"v":89.4464940149831,"d":"89.45"},{"v":1.31100377636713,"d":"1.31"},{"v":0.390671841271558,"d":"0.39"},{"v":0.85274717030607,"d":"0.85"},{"v":0.984976416228804,"d":"0.98"},"up","no"]
["MSTRG.8399","OSCAR","ENST00000391761;ENST00000358375;ENST00000356532;ENST00000359649;ENST00000391760;ENST00000611261;ENST00000351806;ENST00000284648;ENST00000616447","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005886(plasma membrane);GO:0005576(extracellular region);GO:0050776(regulation of immune response);GO:0070062(extracellular exosome);GO:0043312(neutrophil degranulation);GO:0035580(specific granule lumen);GO:1904724(tertiary granule lumen);GO:1904724(tertiary granule lumen)","04380(Osteoclast differentiation);04380(Osteoclast differentiation)","K14377","NA","osteoclast associated, immunoglobulin-like receptor [Source:HGNC Symbol;Acc:HGNC:29960]",{"v":7.2636796126558,"d":"7.26"},{"v":5.53645126797699,"d":"5.54"},{"v":1.31197390911199,"d":"1.31"},{"v":0.391739029735704,"d":"0.39"},{"v":0.854752696916566,"d":"0.85"},{"v":0.985590377870293,"d":"0.99"},"up","no"]
["MSTRG.4658","SETD3","ENST00000331768;ENST00000329331;ENST00000630307;ENST00000489770;ENST00000446066;ENST00000453938;ENST00000357563;ENST00000436070;ENST00000453764","GO:0005634(nucleus);GO:0008168(methyltransferase activity);GO:0016740(transferase activity);GO:0032259(methylation);GO:0003713(transcription coactivator activity);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0016569(covalent chromatin modification);GO:0001102(RNA polymerase II activating transcription factor binding);GO:0018024(histone-lysine N-methyltransferase activity);GO:0042800(histone methyltransferase activity (H3-K4 specific));GO:0046975(histone methyltransferase activity (H3-K36 specific));GO:0010452(histone H3-K36 methylation);GO:0018022(peptidyl-lysine methylation);GO:0018023(peptidyl-lysine trimethylation);GO:0018026(peptidyl-lysine monomethylation);GO:0018027(peptidyl-lysine dimethylation);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0051149(positive regulation of muscle cell differentiation);GO:0051568(histone H3-K4 methylation);GO:0000790(nuclear chromatin);GO:0045893(positive regulation of transcription, DNA-templated);GO:0005654(nucleoplasm);GO:1903506(regulation of nucleic acid-templated transcription);GO:1903506(regulation of nucleic acid-templated transcription)","00310(Lysine degradation);00310(Lysine degradation)","K19199","EC:2.1.1.43","SET domain containing 3 [Source:HGNC Symbol;Acc:HGNC:20493]",{"v":6.30221387625289,"d":"6.30"},{"v":4.81628843600617,"d":"4.82"},{"v":1.30852085791583,"d":"1.31"},{"v":0.387936921231114,"d":"0.39"},{"v":0.857398529273521,"d":"0.86"},{"v":0.98664101515048,"d":"0.99"},"up","no"]
["MSTRG.1316","CHI3L1","ENST00000473185;ENST00000255409;MSTRG.1316.1;ENST00000404436;ENST00000478742;ENST00000472064","GO:0005737(cytoplasm);GO:0005615(extracellular space);GO:0030246(carbohydrate binding);GO:0005975(carbohydrate metabolic process);GO:0005783(endoplasmic reticulum);GO:0005576(extracellular region);GO:0006915(apoptotic process);GO:0005578(proteinaceous extracellular matrix);GO:0048471(perinuclear region of cytoplasm);GO:0008061(chitin binding);GO:0006954(inflammatory response);GO:0007250(activation of NF-kappaB-inducing kinase activity);GO:0010800(positive regulation of peptidyl-threonine phosphorylation);GO:0045766(positive regulation of angiogenesis);GO:0051897(positive regulation of protein kinase B signaling);GO:0071347(cellular response to interleukin-1);GO:0071356(cellular response to tumor necrosis factor);GO:0072606(interleukin-8 secretion);GO:0070062(extracellular exosome);GO:0043312(neutrophil degranulation);GO:0070374(positive regulation of ERK1 and ERK2 cascade);GO:0070555(response to interleukin-1);GO:0051216(cartilage development);GO:0035580(specific granule lumen);GO:0034612(response to tumor necrosis factor);GO:0005201(extracellular matrix structural constituent);GO:0009612(response to mechanical stimulus);GO:0030324(lung development);GO:0070741(response to interleukin-6);GO:0070741(response to interleukin-6)","NA","NA","NA","chitinase 3 like 1 [Source:HGNC Symbol;Acc:HGNC:1932]",{"v":16.0761351643192,"d":"16.08"},{"v":12.2948034122653,"d":"12.29"},{"v":1.30755528374546,"d":"1.31"},{"v":0.386871945247978,"d":"0.39"},{"v":0.858116750284547,"d":"0.86"},{"v":0.986859756491825,"d":"0.99"},"up","no"]
["MSTRG.11215","SLC25A36","ENST00000507429;ENST00000324194;ENST00000512506;ENST00000511757;ENST00000502594;ENST00000513887;ENST00000502756;ENST00000512023;ENST00000515813;ENST00000446041;ENST00000631654;ENST00000393015;ENST00000453248;ENST00000502866;ENST00000514629","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0055085(transmembrane transport);GO:0005743(mitochondrial inner membrane);GO:0005739(mitochondrion);GO:0006839(mitochondrial transport);GO:0007005(mitochondrion organization);GO:0000002(mitochondrial genome maintenance);GO:0051881(regulation of mitochondrial membrane potential);GO:0015218(pyrimidine nucleotide transmembrane transporter activity);GO:0006864(pyrimidine nucleotide transport);GO:1990519(mitochondrial pyrimidine nucleotide import);GO:1990519(mitochondrial pyrimidine nucleotide import)","NA","NA","NA","solute carrier family 25 member 36 [Source:HGNC Symbol;Acc:HGNC:25554]",{"v":0.562779038266681,"d":"0.56"},{"v":0.429348897380619,"d":"0.43"},{"v":1.3107732235953,"d":"1.31"},{"v":0.390418106997857,"d":"0.39"},{"v":0.859895094393912,"d":"0.86"},{"v":0.987340491516364,"d":"0.99"},"up","no"]
["MSTRG.11987","GUSBP1","ENST00000449061;ENST00000508973;ENST00000509649;ENST00000607545;ENST00000508260","NA","NA","NA","NA","glucuronidase, beta pseudogene 1 [Source:HGNC Symbol;Acc:HGNC:13670]",{"v":0.470703048943089,"d":"0.47"},{"v":0.356415059674797,"d":"0.36"},{"v":1.32065982108773,"d":"1.32"},{"v":0.401258901382782,"d":"0.40"},{"v":0.861391754406906,"d":"0.86"},{"v":0.988019222968083,"d":"0.99"},"up","no"]
["ENSG00000167962","ZNF598","ENST00000565396;ENST00000562988;ENST00000564824;ENST00000567008;ENST00000562103;ENST00000563630;ENST00000567625;ENST00000561787","GO:0003676(nucleic acid binding);GO:0003676(nucleic acid binding)","NA","NA","NA","zinc finger protein 598 [Source:HGNC Symbol;Acc:HGNC:28079]",{"v":1.7447887266539,"d":"1.74"},{"v":1.33314124654329,"d":"1.33"},{"v":1.30878009451585,"d":"1.31"},{"v":0.388222711337242,"d":"0.39"},{"v":0.863041032379282,"d":"0.86"},{"v":0.988019222968083,"d":"0.99"},"up","no"]
["ENSG00000120162","MOB3B","ENST00000262244","GO:0046872(metal ion binding);GO:0005515(protein binding)","NA","NA","NA","MOB kinase activator 3B [Source:HGNC Symbol;Acc:HGNC:23825]",{"v":0.475138070551714,"d":"0.48"},{"v":0.362284594045435,"d":"0.36"},{"v":1.31150503874897,"d":"1.31"},{"v":0.391223350389165,"d":"0.39"},{"v":0.864747252985683,"d":"0.86"},{"v":0.98820580074148,"d":"0.99"},"up","no"]
["MSTRG.2027","LHPP","ENST00000368842;ENST00000486535;ENST00000368839;ENST00000481452;ENST00000482963;ENST00000492187;ENST00000487190;ENST00000493240;ENST00000392757","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016607(nuclear speck);GO:0046872(metal ion binding);GO:0005829(cytosol);GO:0016787(hydrolase activity);GO:0042803(protein homodimerization activity);GO:0000287(magnesium ion binding);GO:0006470(protein dephosphorylation);GO:0009168(purine ribonucleoside monophosphate biosynthetic process);GO:0006796(phosphate-containing compound metabolic process);GO:0016791(phosphatase activity);GO:0004427(inorganic diphosphatase activity);GO:0016311(dephosphorylation);GO:0008969(phosphohistidine phosphatase activity);GO:0008969(phosphohistidine phosphatase activity)","00190(Oxidative phosphorylation);00190(Oxidative phosphorylation)","K11725","EC:3.6.1.1;EC:3.1.3.-","phospholysine phosphohistidine inorganic pyrophosphate phosphatase [Source:HGNC Symbol;Acc:HGNC:30042]",{"v":2.98308990575787,"d":"2.98"},{"v":2.66890842765748,"d":"2.67"},{"v":1.1177190925116,"d":"1.12"},{"v":0.160557652615737,"d":"0.16"},{"v":0.865061171199215,"d":"0.87"},{"v":0.98820580074148,"d":"0.99"},"up","no"]
["MSTRG.1816","AP3M1","ENST00000355264;ENST00000372745;ENST00000487653;ENST00000480373","GO:0006810(transport);GO:0016020(membrane);GO:0006886(intracellular protein transport);GO:0015031(protein transport);GO:0016192(vesicle-mediated transport);GO:0005794(Golgi apparatus);GO:0005765(lysosomal membrane);GO:0008089(anterograde axonal transport);GO:0048490(anterograde synaptic vesicle transport);GO:0030131(clathrin adaptor complex);GO:1904115(axon cytoplasm);GO:0005515(protein binding);GO:0030659(cytoplasmic vesicle membrane);GO:0031410(cytoplasmic vesicle);GO:0005764(lysosome);GO:0017137(Rab GTPase binding);GO:0006622(protein targeting to lysosome);GO:0006622(protein targeting to lysosome)","04142(Lysosome);04142(Lysosome)","K12398","NA","adaptor related protein complex 3 mu 1 subunit [Source:HGNC Symbol;Acc:HGNC:569]",{"v":5.99618864749662,"d":"6.00"},{"v":4.60801639580514,"d":"4.61"},{"v":1.30125158689869,"d":"1.30"},{"v":0.37989992291718,"d":"0.38"},{"v":0.866039533498922,"d":"0.87"},{"v":0.98820580074148,"d":"0.99"},"up","no"]
["MSTRG.531","LRRC41","ENST00000617190;ENST00000343304;ENST00000615587;ENST00000617760;ENST00000496156;ENST00000469150;ENST00000472710;ENST00000498402","GO:0016020(membrane);GO:0016567(protein ubiquitination);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0043687(post-translational protein modification);GO:0042803(protein homodimerization activity);GO:0042803(protein homodimerization activity)","NA","NA","NA","leucine rich repeat containing 41 [Source:HGNC Symbol;Acc:HGNC:16917]",{"v":1.82861647211248,"d":"1.83"},{"v":1.40582883174529,"d":"1.41"},{"v":1.30073905927958,"d":"1.30"},{"v":0.379331572631173,"d":"0.38"},{"v":0.867257184581506,"d":"0.87"},{"v":0.98820580074148,"d":"0.99"},"up","no"]
["ENSG00000283839","AC096667.1","ENST00000640078","NA","NA","NA","NA",null,{"v":0.873047,"d":"0.87"},{"v":0.786642,"d":"0.79"},{"v":1.10984030855205,"d":"1.11"},{"v":0.150352106634838,"d":"0.15"},{"v":0.869140968802068,"d":"0.87"},{"v":0.988750923765707,"d":"0.99"},"up","no"]
["MSTRG.9734","TTI1","ENST00000373447;ENST00000473288;ENST00000373448","GO:0005737(cytoplasm);GO:0005515(protein binding);GO:0032006(regulation of TOR signaling);GO:0031931(TORC1 complex);GO:0031932(TORC2 complex);GO:0031932(TORC2 complex)","04150(mTOR signaling pathway);04150(mTOR signaling pathway)","K20403","NA","TELO2 interacting protein 1 [Source:HGNC Symbol;Acc:HGNC:29029]",{"v":2.94429507189105,"d":"2.94"},{"v":2.26717716008037,"d":"2.27"},{"v":1.29866122671537,"d":"1.30"},{"v":0.377025133418408,"d":"0.38"},{"v":0.869802964970136,"d":"0.87"},{"v":0.988750923765707,"d":"0.99"},"up","no"]
["ENSG00000231607","DLEU2","ENST00000235290;ENST00000458725;ENST00000621282;ENST00000425586;ENST00000443587;ENST00000449579","NA","NA","NA","NA","deleted in lymphocytic leukemia 2 (non-protein coding) [Source:HGNC Symbol;Acc:HGNC:13748]",{"v":0.491294821869489,"d":"0.49"},{"v":0.442112909269057,"d":"0.44"},{"v":1.11124287838992,"d":"1.11"},{"v":0.152174173300745,"d":"0.15"},{"v":0.871660519351025,"d":"0.87"},{"v":0.98883978447106,"d":"0.99"},"up","no"]
["ENSG00000156853","ZNF689","ENST00000287461","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0005622(intracellular);GO:0035914(skeletal muscle cell differentiation)","NA","NA","NA","zinc finger protein 689 [Source:HGNC Symbol;Acc:HGNC:25173]",{"v":2.206089868478,"d":"2.21"},{"v":1.97377202909353,"d":"1.97"},{"v":1.11770246814733,"d":"1.12"},{"v":0.160536194571037,"d":"0.16"},{"v":0.873153936808628,"d":"0.87"},{"v":0.98883978447106,"d":"0.99"},"up","no"]
["MSTRG.5482","TMEM8A;MRPL28","MSTRG.5482.13;ENST00000199706;ENST00000431232;ENST00000469744;ENST00000250930;ENST00000481453;ENST00000483764;ENST00000389675;ENST00000467452;ENST00000427313;MSTRG.5482.1;ENST00000461550;ENST00000441883;ENST00000447696;ENST00000448854;ENST00000424078;ENST00000475348;ENST00000450882;ENST00000476735","GO:0003723(RNA binding);GO:0006412(translation);GO:0005829(cytosol);GO:0005739(mitochondrion);GO:0030529(intracellular ribonucleoprotein complex);GO:0003735(structural constituent of ribosome);GO:0005840(ribosome);GO:0005515(protein binding);GO:0005743(mitochondrial inner membrane);GO:0070125(mitochondrial translational elongation);GO:0070126(mitochondrial translational termination);GO:0005761(mitochondrial ribosome);GO:0005762(mitochondrial large ribosomal subunit);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0007155(cell adhesion);GO:0005765(lysosomal membrane);GO:0005887(integral component of plasma membrane);GO:0005886(plasma membrane);GO:0003674(molecular_function);GO:0008150(biological_process);GO:0070062(extracellular exosome);GO:0070062(extracellular exosome)","03010(Ribosome);03010(Ribosome)","K02902","NA","mitochondrial ribosomal protein L28 [Source:HGNC Symbol;Acc:HGNC:14484];transmembrane protein 8A [Source:HGNC Symbol;Acc:HGNC:17205]",{"v":12.3727230902854,"d":"12.37"},{"v":11.0385269599341,"d":"11.04"},{"v":1.12086722578057,"d":"1.12"},{"v":0.164615391387919,"d":"0.16"},{"v":0.873613001002026,"d":"0.87"},{"v":0.98883978447106,"d":"0.99"},"up","no"]
["MSTRG.5818","INO80E","ENST00000563197;ENST00000568043;ENST00000562441;ENST00000569957;ENST00000620599;ENST00000567987;ENST00000540562;ENST00000380503;ENST00000304516;ENST00000563040;ENST00000567065;ENST00000567705;ENST00000562291;ENST00000567254","GO:0005634(nucleus);GO:0005730(nucleolus);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0006281(DNA repair);GO:0005515(protein binding);GO:0006310(DNA recombination);GO:0006974(cellular response to DNA damage stimulus);GO:0031011(Ino80 complex);GO:0006260(DNA replication);GO:0005654(nucleoplasm);GO:0016579(protein deubiquitination);GO:0016579(protein deubiquitination)","NA","NA","NA","INO80 complex subunit E [Source:HGNC Symbol;Acc:HGNC:26905]",{"v":1.94057255052666,"d":"1.94"},{"v":1.73158484907834,"d":"1.73"},{"v":1.12069157428789,"d":"1.12"},{"v":0.164389288429627,"d":"0.16"},{"v":0.87526486023388,"d":"0.88"},{"v":0.989144688779297,"d":"0.99"},"up","no"]
["MSTRG.13573","AOAH","ENST00000480201;ENST00000617267;ENST00000612871;ENST00000617537;ENST00000614254;ENST00000435386;ENST00000491444;ENST00000487014;ENST00000414637;ENST00000495942;ENST00000621510","GO:0016787(hydrolase activity);GO:0005576(extracellular region);GO:0016788(hydrolase activity, acting on ester bonds);GO:0006954(inflammatory response);GO:0006629(lipid metabolic process);GO:0003824(catalytic activity);GO:0004465(lipoprotein lipase activity);GO:0050528(acyloxyacyl hydrolase activity);GO:0008653(lipopolysaccharide metabolic process);GO:0050728(negative regulation of inflammatory response);GO:0050728(negative regulation of inflammatory response)","NA","NA","NA","acyloxyacyl hydrolase [Source:HGNC Symbol;Acc:HGNC:548]",{"v":31.50173862849,"d":"31.50"},{"v":28.0498938720798,"d":"28.05"},{"v":1.12306088472748,"d":"1.12"},{"v":0.167436142977493,"d":"0.17"},{"v":0.876754783892858,"d":"0.88"},{"v":0.989768961344198,"d":"0.99"},"up","no"]
["ENSG00000122591","FAM126A","ENST00000432176;ENST00000467005;ENST00000465661;ENST00000440481;ENST00000409763;ENST00000421730","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0004871(signal transducer activity);GO:0007165(signal transduction);GO:0005515(protein binding);GO:0090002(establishment of protein localization to plasma membrane);GO:0042552(myelination);GO:0046854(phosphatidylinositol phosphorylation);GO:0043005(neuron projection);GO:0043005(neuron projection)","NA","NA","NA","family with sequence similarity 126 member A [Source:HGNC Symbol;Acc:HGNC:24587]",{"v":1.35667643513346,"d":"1.36"},{"v":1.20823744161666,"d":"1.21"},{"v":1.12285581327308,"d":"1.12"},{"v":0.167172682118607,"d":"0.17"},{"v":0.878356918664519,"d":"0.88"},{"v":0.990148881002467,"d":"0.99"},"up","no"]
["MSTRG.15448","AIFM1","ENST00000287295;ENST00000535724;ENST00000460436;ENST00000533719;ENST00000319908","GO:0016491(oxidoreductase activity);GO:0050660(flavin adenine dinucleotide binding);GO:0055114(oxidation-reduction process);GO:0046983(protein dimerization activity);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005743(mitochondrial inner membrane);GO:0003677(DNA binding);GO:0005829(cytosol);GO:0005739(mitochondrion);GO:0005515(protein binding);GO:0006915(apoptotic process);GO:0048471(perinuclear region of cytoplasm);GO:0005758(mitochondrial intermembrane space);GO:0043065(positive regulation of apoptotic process);GO:0030261(chromosome condensation);GO:0006919(activation of cysteine-type endopeptidase activity involved in apoptotic process);GO:0070059(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress);GO:0016174(NAD(P)H oxidase activity);GO:0016651(oxidoreductase activity, acting on NAD(P)H);GO:0071949(FAD binding);GO:0002931(response to ischemia);GO:0009636(response to toxic substance);GO:0010942(positive regulation of cell death);GO:0043525(positive regulation of neuron apoptotic process);GO:0051402(neuron apoptotic process);GO:0070301(cellular response to hydrogen peroxide);GO:0071392(cellular response to estradiol stimulus);GO:0071732(cellular response to nitric oxide);GO:0090650(cellular response to oxygen-glucose deprivation);GO:1902065(response to L-glutamate);GO:1902510(regulation of apoptotic DNA fragmentation);GO:1904045(cellular response to aldosterone);GO:1904045(cellular response to aldosterone)","04210(Apoptosis);04217(Necroptosis);04217(Necroptosis)","K04727","EC:1.-.-.-","apoptosis inducing factor mitochondria associated 1 [Source:HGNC Symbol;Acc:HGNC:8768]",{"v":4.11812832667877,"d":"4.12"},{"v":3.66596089171204,"d":"3.67"},{"v":1.12334213275133,"d":"1.12"},{"v":0.167797391718902,"d":"0.17"},{"v":0.880225623248818,"d":"0.88"},{"v":0.990148881002467,"d":"0.99"},"up","no"]
["ENSG00000176928","GCNT4","ENST00000322348","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016740(transferase activity);GO:0016757(transferase activity, transferring glycosyl groups);GO:0005794(Golgi apparatus);GO:0000139(Golgi membrane);GO:0006486(protein glycosylation);GO:0008375(acetylglucosaminyltransferase activity);GO:0005975(carbohydrate metabolic process);GO:0006493(protein O-linked glycosylation);GO:0016266(O-glycan processing);GO:0003829(beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity);GO:0008109(N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity);GO:0002121(inter-male aggressive behavior);GO:0042403(thyroid hormone metabolic process);GO:0048729(tissue morphogenesis);GO:0048872(homeostasis of number of cells);GO:0060993(kidney morphogenesis)","00512(Mucin type O-glycan biosynthesis)","K09663","EC:2.4.1.-","glucosaminyl (N-acetyl) transferase 4, core 2 [Source:HGNC Symbol;Acc:HGNC:17973]",{"v":1.943916,"d":"1.94"},{"v":1.727637,"d":"1.73"},{"v":1.12518775645578,"d":"1.13"},{"v":0.170165759403514,"d":"0.17"},{"v":0.88065517767152,"d":"0.88"},{"v":0.990148881002467,"d":"0.99"},"up","no"]
["MSTRG.4721","ZFYVE21","ENST00000311141;ENST00000556610;ENST00000553724;ENST00000554757;ENST00000554255;ENST00000555163;ENST00000556795;ENST00000216602;ENST00000555501;ENST00000602552;ENST00000554630","GO:0005829(cytosol);GO:0046872(metal ion binding);GO:0005515(protein binding);GO:0030054(cell junction);GO:0031410(cytoplasmic vesicle);GO:0005925(focal adhesion);GO:0005768(endosome);GO:0042147(retrograde transport, endosome to Golgi);GO:0046854(phosphatidylinositol phosphorylation);GO:0010008(endosome membrane);GO:0000285(1-phosphatidylinositol-3-phosphate 5-kinase activity);GO:0000285(1-phosphatidylinositol-3-phosphate 5-kinase activity)","NA","NA","NA","zinc finger FYVE-type containing 21 [Source:HGNC Symbol;Acc:HGNC:20760]",{"v":1.06947611001192,"d":"1.07"},{"v":0.952604493325387,"d":"0.95"},{"v":1.12268640081526,"d":"1.12"},{"v":0.166954997043086,"d":"0.17"},{"v":0.881174064246851,"d":"0.88"},{"v":0.990148881002467,"d":"0.99"},"up","no"]
["MSTRG.10654","GHRL","ENST00000335542;ENST00000430179;ENST00000457360;ENST00000481287;ENST00000439975;ENST00000476283","GO:0005576(extracellular region);GO:0008154(actin polymerization or depolymerization);GO:0005515(protein binding);GO:0007186(G-protein coupled receptor signaling pathway);GO:0005615(extracellular space);GO:0005179(hormone activity);GO:0098794(postsynapse);GO:0061098(positive regulation of protein tyrosine kinase activity);GO:0030424(axon);GO:0050728(negative regulation of inflammatory response);GO:0006006(glucose metabolic process);GO:0016608(growth hormone-releasing hormone activity);GO:0042127(regulation of cell proliferation);GO:0043066(negative regulation of apoptotic process);GO:0001664(G-protein coupled receptor binding);GO:0034774(secretory granule lumen);GO:0051216(cartilage development);GO:0005788(endoplasmic reticulum lumen);GO:0001937(negative regulation of endothelial cell proliferation);GO:0016525(negative regulation of angiogenesis);GO:0007204(positive regulation of cytosolic calcium ion concentration);GO:0043627(response to estrogen);GO:0000187(activation of MAPK activity);GO:0060399(positive regulation of growth hormone receptor signaling pathway);GO:0060124(positive regulation of growth hormone secretion);GO:0008343(adult feeding behavior);GO:0032100(positive regulation of appetite);GO:0009725(response to hormone);GO:0042322(negative regulation of circadian sleep/wake cycle, REM sleep);GO:0051464(positive regulation of cortisol secretion);GO:0032024(positive regulation of insulin secretion);GO:0046697(decidualization);GO:0030296(protein tyrosine kinase activator activity);GO:0051965(positive regulation of synapse assembly);GO:0042536(negative regulation of tumor necrosis factor biosynthetic process);GO:0009755(hormone-mediated signaling pathway);GO:0030252(growth hormone secretion);GO:0032691(negative regulation of interleukin-1 beta production);GO:0040018(positive regulation of multicellular organism growth);GO:0045409(negative regulation of interleukin-6 biosynthetic process);GO:0031768(ghrelin receptor binding);GO:0001696(gastric acid secretion);GO:0016358(dendrite development);GO:0031667(response to nutrient levels);GO:0032095(regulation of response to food);GO:0032097(positive regulation of response to food);GO:0035483(gastric emptying);GO:0035774(positive regulation of insulin secretion involved in cellular response to glucose stimulus);GO:0040010(positive regulation of growth rate);GO:0040013(negative regulation of locomotion);GO:0043400(cortisol secretion);GO:0045927(positive regulation of growth);GO:0046010(positive regulation of circadian sleep/wake cycle, non-REM sleep);GO:0046676(negative regulation of insulin secretion);GO:0051461(positive regulation of corticotropin secretion);GO:0051602(response to electrical stimulus);GO:0051969(regulation of transmission of nerve impulse);GO:0060079(excitatory postsynaptic potential);GO:0120058(-);GO:1903012(positive regulation of bone development);GO:1903672(positive regulation of sprouting angiogenesis);GO:1904000(positive regulation of eating behavior);GO:1904179(positive regulation of adipose tissue development);GO:1904306(positive regulation of gastro-intestinal system smooth muscle contraction);GO:1904346(positive regulation of gastric mucosal blood circulation);GO:1904349(positive regulation of small intestine smooth muscle contraction);GO:1904468(negative regulation of tumor necrosis factor secretion);GO:1905333(regulation of gastric motility);GO:1905564(positive regulation of vascular endothelial cell proliferation);GO:2000253(positive regulation of feeding behavior);GO:2000506(negative regulation of energy homeostasis);GO:2000507(positive regulation of energy homeostasis);GO:0005737(cytoplasm);GO:0005737(cytoplasm)","04024(cAMP signaling pathway);04024(cAMP signaling pathway)","K05254","NA","ghrelin and obestatin prepropeptide [Source:HGNC Symbol;Acc:HGNC:18129]",{"v":1.34096813178295,"d":"1.34"},{"v":1.03532409447674,"d":"1.04"},{"v":1.29521580627435,"d":"1.30"},{"v":0.37319249691006,"d":"0.37"},{"v":0.882889059667132,"d":"0.88"},{"v":0.990693903202317,"d":"0.99"},"up","no"]
["MSTRG.14982","CDK9","ENST00000373264;ENST00000498339;ENST00000480353;ENST00000491521;ENST00000421939","GO:0004672(protein kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0000166(nucleotide binding);GO:0004674(protein serine/threonine kinase activity);GO:0005654(nucleoplasm);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0005515(protein binding);GO:0006281(DNA repair);GO:0006974(cellular response to DNA damage stimulus);GO:0000932(P-body);GO:0000979(RNA polymerase II core promoter sequence-specific DNA binding);GO:0003682(chromatin binding);GO:0008134(transcription factor binding);GO:0008353(RNA polymerase II carboxy-terminal domain kinase activity);GO:0017069(snRNA binding);GO:0019901(protein kinase binding);GO:0044212(transcription regulatory region DNA binding);GO:0010613(positive regulation of cardiac muscle hypertrophy);GO:0033129(positive regulation of histone phosphorylation);GO:0042493(response to drug);GO:2001168(positive regulation of histone H2B ubiquitination);GO:0008024(cyclin/CDK positive transcription elongation factor complex);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0071157(negative regulation of cell cycle arrest);GO:0006368(transcription elongation from RNA polymerase II promoter);GO:0031297(replication fork processing);GO:0006366(transcription from RNA polymerase II promoter);GO:0050434(positive regulation of viral transcription);GO:1900364(negative regulation of mRNA polyadenylation);GO:0003677(DNA binding);GO:0016605(PML body);GO:0042795(snRNA transcription from RNA polymerase II promoter);GO:0008023(transcription elongation factor complex);GO:0008283(cell proliferation);GO:0006367(transcription initiation from RNA polymerase II promoter);GO:0097322(7SK snRNA binding);GO:0001223(transcription coactivator binding);GO:0071345(cellular response to cytokine stimulus);GO:0005694(chromosome);GO:0006282(regulation of DNA repair);GO:0004693(cyclin-dependent protein serine/threonine kinase activity);GO:0070816(phosphorylation of RNA polymerase II C-terminal domain);GO:0030332(cyclin binding);GO:0031056(regulation of histone modification);GO:0051147(regulation of muscle cell differentiation);GO:1903839(positive regulation of mRNA 3'-UTR binding);GO:1903839(positive regulation of mRNA 3'-UTR binding)","05202(Transcriptional misregulation in cancers);05202(Transcriptional misregulation in cancers)","K02211","EC:2.7.11.22;EC:2.7.11.23","cyclin dependent kinase 9 [Source:HGNC Symbol;Acc:HGNC:1780]",{"v":10.3067625466667,"d":"10.31"},{"v":9.14453276666667,"d":"9.14"},{"v":1.12709558920676,"d":"1.13"},{"v":0.172609875959531,"d":"0.17"},{"v":0.884541816772453,"d":"0.88"},{"v":0.990847033405502,"d":"0.99"},"up","no"]
["ENSG00000148832","PAOX","ENST00000278060;ENST00000476834;ENST00000483211;ENST00000357296;ENST00000356306","GO:0005737(cytoplasm);GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0005777(peroxisome);GO:0005102(receptor binding);GO:0005782(peroxisomal matrix);GO:0006596(polyamine biosynthetic process);GO:0009447(putrescine catabolic process);GO:0046592(polyamine oxidase activity);GO:0052899(N(1),N(12)-diacetylspermine:oxygen oxidoreductase (3-acetamidopropanal-forming) activity);GO:0052901(spermine:oxygen oxidoreductase (spermidine-forming) activity);GO:0052902(spermidine:oxygen oxidoreductase (3-aminopropanal-forming) activity);GO:0052903(N1-acetylspermine:oxygen oxidoreductase (3-acetamidopropanal-forming) activity);GO:0052904(N1-acetylspermidine:oxygen oxidoreductase (3-acetamidopropanal-forming) activity);GO:0006598(polyamine catabolic process);GO:0008215(spermine metabolic process);GO:0009446(putrescine biosynthetic process);GO:0046203(spermidine catabolic process);GO:0046208(spermine catabolic process);GO:1901307(positive regulation of spermidine biosynthetic process);GO:1901307(positive regulation of spermidine biosynthetic process)","04146(Peroxisome);04146(Peroxisome)","K00308","EC:1.5.3.13","polyamine oxidase [Source:HGNC Symbol;Acc:HGNC:20837]",{"v":1.06142700746596,"d":"1.06"},{"v":0.943001313131313,"d":"0.94"},{"v":1.1255838063909,"d":"1.13"},{"v":0.170673477994476,"d":"0.17"},{"v":0.885103671065377,"d":"0.89"},{"v":0.990920042722771,"d":"0.99"},"up","no"]
["MSTRG.13029","FRS3","ENST00000373018;ENST00000259748;ENST00000466420","GO:0005622(intracellular);GO:0016020(membrane);GO:0043547(positive regulation of GTPase activity);GO:0005515(protein binding);GO:0005158(insulin receptor binding);GO:0005886(plasma membrane);GO:0042802(identical protein binding);GO:0000165(MAPK cascade);GO:0007165(signal transduction);GO:0005088(Ras guanyl-nucleotide exchange factor activity);GO:0008543(fibroblast growth factor receptor signaling pathway);GO:0005104(fibroblast growth factor receptor binding);GO:0005104(fibroblast growth factor receptor binding)","NA","NA","NA","fibroblast growth factor receptor substrate 3 [Source:HGNC Symbol;Acc:HGNC:16970]",{"v":0.566637699090273,"d":"0.57"},{"v":0.505783610216935,"d":"0.51"},{"v":1.12031645083801,"d":"1.12"},{"v":0.163906301541723,"d":"0.16"},{"v":0.887043749767548,"d":"0.89"},{"v":0.991130069544055,"d":"0.99"},"up","no"]
["MSTRG.10710","RFTN1","ENST00000432519;ENST00000334133;ENST00000470458;ENST00000451036;ENST00000483671;ENST00000453536;ENST00000607320;ENST00000441460;ENST00000431547;ENST00000484752","GO:0016020(membrane);GO:0005886(plasma membrane);GO:0045121(membrane raft);GO:0070062(extracellular exosome);GO:0043234(protein complex);GO:0005737(cytoplasm);GO:0050852(T cell receptor signaling pathway);GO:0050853(B cell receptor signaling pathway);GO:0043330(response to exogenous dsRNA);GO:0003725(double-stranded RNA binding);GO:0005768(endosome);GO:0001765(membrane raft assembly);GO:1903044(protein localization to membrane raft);GO:0040007(growth);GO:0002457(T cell antigen processing and presentation);GO:0032596(protein transport into membrane raft);GO:0032620(interleukin-17 production);GO:0033227(dsRNA transport);GO:0034138(toll-like receptor 3 signaling pathway);GO:0034138(toll-like receptor 3 signaling pathway)","NA","NA","NA","raftlin, lipid raft linker 1 [Source:HGNC Symbol;Acc:HGNC:30278]",{"v":5.28611937123116,"d":"5.29"},{"v":4.67745502407873,"d":"4.68"},{"v":1.13012724740679,"d":"1.13"},{"v":0.176485222965459,"d":"0.18"},{"v":0.887775530957559,"d":"0.89"},{"v":0.991130069544055,"d":"0.99"},"up","no"]
["MSTRG.8150","AKT2","ENST00000391844;ENST00000483166;ENST00000392038;ENST00000358335;ENST00000578123;ENST00000601166;ENST00000491778;ENST00000311278;ENST00000423127;ENST00000392037;ENST00000578310;ENST00000492463;ENST00000578615;ENST00000476247;ENST00000486647;ENST00000391845;ENST00000489375;ENST00000583859;ENST00000427375;ENST00000424901;ENST00000578975;ENST00000480878;ENST00000579345;ENST00000496089;ENST00000578282;ENST00000581582;ENST00000486368;ENST00000537834;ENST00000580878;ENST00000498350;ENST00000487537;ENST00000579047;ENST00000416994;ENST00000497948;ENST00000580747;ENST00000584288;ENST00000416362;ENST00000441941","GO:0046326(positive regulation of glucose import);GO:0030335(positive regulation of cell migration);GO:0006810(transport);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0043231(intracellular membrane-bounded organelle);GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0005829(cytosol);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0007165(signal transduction);GO:0006915(apoptotic process);GO:0007275(multicellular organism development);GO:0005975(carbohydrate metabolic process);GO:0008643(carbohydrate transport);GO:0035556(intracellular signal transduction);GO:0005768(endosome);GO:0005654(nucleoplasm);GO:0045444(fat cell differentiation);GO:0001934(positive regulation of protein phosphorylation);GO:0005938(cell cortex);GO:0032587(ruffle membrane);GO:0006417(regulation of translation);GO:0090314(positive regulation of protein targeting to membrane);GO:0043234(protein complex);GO:0005769(early endosome);GO:0006006(glucose metabolic process);GO:0008284(positive regulation of cell proliferation);GO:0005978(glycogen biosynthetic process);GO:0018105(peptidyl-serine phosphorylation);GO:0030334(regulation of cell migration);GO:0043066(negative regulation of apoptotic process);GO:0006464(cellular protein modification process);GO:0008286(insulin receptor signaling pathway);GO:2000147(positive regulation of cell motility);GO:0060644(mammary gland epithelial cell differentiation);GO:0032869(cellular response to insulin stimulus);GO:0005977(glycogen metabolic process);GO:0045725(positive regulation of glycogen biosynthetic process);GO:0031340(positive regulation of vesicle fusion);GO:0010748(negative regulation of plasma membrane long-chain fatty acid transport);GO:0010907(positive regulation of glucose metabolic process);GO:0010918(positive regulation of mitochondrial membrane potential);GO:0032000(positive regulation of fatty acid beta-oxidation);GO:0032287(peripheral nervous system myelin maintenance);GO:0065002(intracellular protein transmembrane transport);GO:0071156(regulation of cell cycle arrest);GO:0071486(cellular response to high light intensity);GO:0072659(protein localization to plasma membrane);GO:0090630(activation of GTPase activity);GO:0097473(retinal rod cell apoptotic process);GO:2001275(positive regulation of glucose import in response to insulin stimulus);GO:2001275(positive regulation of glucose import in response to insulin stimulus)","04014(Ras signaling pathway);04015(Rap1 signaling pathway);04010(MAPK signaling pathway);04012(ErbB signaling pathway);04370(VEGF signaling pathway);04371(Apelin signaling pathway);04630(Jak-STAT signaling pathway);04668(TNF signaling pathway);04066(HIF-1 signaling pathway);04068(FoxO signaling pathway);04072(Phospholipase D signaling pathway);04071(Sphingolipid signaling pathway);04024(cAMP signaling pathway);04022(cGMP - PKG signaling pathway);04151(PI3K-Akt signaling pathway);04152(AMPK signaling pathway);04150(mTOR signaling pathway);04140(Autophagy - animal);04210(Apoptosis);04218(Cellular senescence);04510(Focal adhesion);04550(Signaling pathways regulating pluripotency of stem cells);04611(Platelet activation);04620(Toll-like receptor signaling pathway);04660(T cell receptor signaling pathway);04662(B cell receptor signaling pathway);04664(Fc epsilon RI signaling pathway);04666(Fc gamma R-mediated phagocytosis);04062(Chemokine signaling pathway);04910(Insulin signaling pathway);04922(Glucagon signaling pathway);04923(Regulation of lipolysis in adipocyte);04920(Adipocytokine signaling pathway);04915(Estrogen signaling pathway);04914(Progesterone-mediated oocyte maturation);04917(Prolactin signaling pathway);04926(Relaxin signaling pathway);04919(Thyroid hormone signaling pathway);04261(Adrenergic signaling in cardiomyocytes);04973(Carbohydrate digestion and absorption);04725(Cholinergic synapse);04728(Dopaminergic synapse);04722(Neurotrophin signaling pathway);04380(Osteoclast differentiation);04211(Longevity regulating pathway - mammal);04213(Longevity regulating pathway - multiple species);05200(Pathways in cancer);05230(Central carbon metabolism in cancer);05231(Choline metabolism in cancer);05205(Proteoglycans in cancer);05210(Colorectal cancer);05212(Pancreatic cancer);05225(Hepatocellular carcinoma);05226(Gastric cancer);05214(Glioma);05221(Acute myeloid leukemia);05220(Chronic myeloid leukemia);05218(Melanoma);05211(Renal cell carcinoma);05215(Prostate cancer);05213(Endometrial cancer);05224(Breast cancer);05222(Small cell lung cancer);05223(Non-small cell lung cancer);05418(Fluid shear stress and atherosclerosis);04932(Non-alcoholic fatty liver disease (NAFLD));04931(Insulin resistance);04933(AGE-RAGE signaling pathway in diabetic complications);05152(Tuberculosis);05166(HTLV-I infection);05162(Measles);05164(Influenza A);05161(Hepatitis B);05160(Hepatitis C);05167(Kaposi's sarcoma-associated herpesvirus infection);05169(Epstein-Barr virus infection);05165(Human papillomavirus infection);05145(Toxoplasmosis);05142(Chagas disease (American trypanosomiasis));01521(EGFR tyrosine kinase inhibitor resistance);01524(Platinum drug resistance);01522(Endocrine resistance);01522(Endocrine resistance)","K04456","EC:2.7.11.1","AKT serine/threonine kinase 2 [Source:HGNC Symbol;Acc:HGNC:392]",{"v":4.62209267549052,"d":"4.62"},{"v":3.60204178736282,"d":"3.60"},{"v":1.28318685577341,"d":"1.28"},{"v":0.35973126884465,"d":"0.36"},{"v":0.889244795725454,"d":"0.89"},{"v":0.991260571196354,"d":"0.99"},"up","no"]
["ENSG00000144554","FANCD2","ENST00000419585;ENST00000431693;ENST00000470757;ENST00000383807;ENST00000480909;ENST00000287647;ENST00000435522;ENST00000483276","GO:0005634(nucleus);GO:0005730(nucleolus);GO:0005829(cytosol);GO:0006281(DNA repair);GO:0005515(protein binding);GO:0006974(cellular response to DNA damage stimulus);GO:0007049(cell cycle);GO:0016604(nuclear body);GO:0005654(nucleoplasm);GO:0036297(interstrand cross-link repair);GO:0010332(response to gamma radiation);GO:0070182(DNA polymerase binding);GO:0007129(synapsis);GO:0007276(gamete generation);GO:0034599(cellular response to oxidative stress);GO:0045589(regulation of regulatory T cell differentiation);GO:0048854(brain morphogenesis);GO:0050727(regulation of inflammatory response);GO:0051090(regulation of sequence-specific DNA binding transcription factor activity);GO:0097150(neuronal stem cell population maintenance);GO:2000348(regulation of CD40 signaling pathway);GO:0000793(condensed chromosome);GO:0000793(condensed chromosome)","03460(Fanconi anemia pathway);03460(Fanconi anemia pathway)","K10891","NA","Fanconi anemia complementation group D2 [Source:HGNC Symbol;Acc:HGNC:3585]",{"v":0.685305184053473,"d":"0.69"},{"v":0.532602059202674,"d":"0.53"},{"v":1.28671148038632,"d":"1.29"},{"v":0.363688593978334,"d":"0.36"},{"v":0.89046280454486,"d":"0.89"},{"v":0.991271525036375,"d":"0.99"},"up","no"]
["MSTRG.11660","G3BP2","ENST00000359707;ENST00000357854;ENST00000509561;ENST00000511868;ENST00000507947;ENST00000395719;ENST00000508510;ENST00000515457;ENST00000510902;ENST00000503660;MSTRG.11660.4;ENST00000507133;ENST00000499709;ENST00000507745;ENST00000509100;ENST00000507701","GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0006810(transport);GO:0051028(mRNA transport);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005622(intracellular);GO:0005515(protein binding);GO:0034063(stress granule assembly);GO:0007265(Ras protein signal transduction);GO:0003729(mRNA binding);GO:0030159(receptor signaling complex scaffold activity);GO:0007253(cytoplasmic sequestering of NF-kappaB);GO:0030529(intracellular ribonucleoprotein complex);GO:0030529(intracellular ribonucleoprotein complex)","NA","NA","NA","G3BP stress granule assembly factor 2 [Source:HGNC Symbol;Acc:HGNC:30291]",{"v":5.06941602721275,"d":"5.07"},{"v":4.47626333631116,"d":"4.48"},{"v":1.13251067829052,"d":"1.13"},{"v":0.179524653312706,"d":"0.18"},{"v":0.891721610054895,"d":"0.89"},{"v":0.991722185172141,"d":"0.99"},"up","no"]
["ENSG00000179922","ZNF784","ENST00000325351","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0002244(hematopoietic progenitor cell differentiation)","NA","NA","NA","zinc finger protein 784 [Source:HGNC Symbol;Acc:HGNC:33111]",{"v":0.952200336734694,"d":"0.95"},{"v":0.851750351797862,"d":"0.85"},{"v":1.11793359958678,"d":"1.12"},{"v":0.160834500889759,"d":"0.16"},{"v":0.893805702199222,"d":"0.89"},{"v":0.992346975722521,"d":"0.99"},"up","no"]
["ENSG00000115170","ACVR1","ENST00000434821;ENST00000409283;ENST00000424669;ENST00000440523;ENST00000412025;ENST00000263640;ENST00000413751;ENST00000410057","GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0060412(ventricular septum morphogenesis);GO:0030335(positive regulation of cell migration);GO:0030509(BMP signaling pathway);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0004702(signal transducer, downstream of receptor, with serine/threonine kinase activity);GO:0023014(signal transduction by protein phosphorylation);GO:0045893(positive regulation of transcription, DNA-templated);GO:0005887(integral component of plasma membrane);GO:0005515(protein binding);GO:0004675(transmembrane receptor protein serine/threonine kinase activity);GO:0007178(transmembrane receptor protein serine/threonine kinase signaling pathway);GO:0005025(transforming growth factor beta receptor activity, type I);GO:0016361(activin receptor activity, type I);GO:0019838(growth factor binding);GO:0048185(activin binding);GO:0050431(transforming growth factor beta binding);GO:0001569(branching involved in blood vessel morphogenesis);GO:0001701(in utero embryonic development);GO:0001702(gastrulation with mouth forming second);GO:0001707(mesoderm formation);GO:0001755(neural crest cell migration);GO:0002526(acute inflammatory response);GO:0003181(atrioventricular valve morphogenesis);GO:0003203(endocardial cushion morphogenesis);GO:0003274(endocardial cushion fusion);GO:0003289(atrial septum primum morphogenesis);GO:0007179(transforming growth factor beta receptor signaling pathway);GO:0007281(germ cell development);GO:0007368(determination of left/right symmetry);GO:0007369(gastrulation);GO:0007498(mesoderm development);GO:0007507(heart development);GO:0010862(positive regulation of pathway-restricted SMAD protein phosphorylation);GO:0032924(activin receptor signaling pathway);GO:0051145(smooth muscle cell differentiation);GO:0060037(pharyngeal system development);GO:0061312(BMP signaling pathway involved in heart development);GO:1905007(positive regulation of epithelial to mesenchymal transition involved in endocardial cushion formation);GO:0045177(apical part of cell);GO:0042803(protein homodimerization activity);GO:0046332(SMAD binding);GO:0030501(positive regulation of bone mineralization);GO:0045669(positive regulation of osteoblast differentiation);GO:0071773(cellular response to BMP stimulus);GO:0060389(pathway-restricted SMAD protein phosphorylation);GO:0018107(peptidyl-threonine phosphorylation);GO:0003183(mitral valve morphogenesis);GO:0017046(peptide hormone binding);GO:2001237(negative regulation of extrinsic apoptotic signaling pathway);GO:0000082(G1/S transition of mitotic cell cycle);GO:0060923(cardiac muscle cell fate commitment);GO:0009968(negative regulation of signal transduction);GO:0003143(embryonic heart tube morphogenesis);GO:0030278(regulation of ossification);GO:0032926(negative regulation of activin receptor signaling pathway);GO:0061445(endocardial cushion cell fate commitment);GO:2000017(positive regulation of determination of dorsal identity);GO:0048179(activin receptor complex);GO:0048179(activin receptor complex)","04350(TGF-beta signaling pathway);04060(Cytokine-cytokine receptor interaction);04550(Signaling pathways regulating pluripotency of stem cells);05418(Fluid shear stress and atherosclerosis);05418(Fluid shear stress and atherosclerosis)","K04675","EC:2.7.11.30","activin A receptor type 1 [Source:HGNC Symbol;Acc:HGNC:171]",{"v":1.85385211854637,"d":"1.85"},{"v":1.45606998421053,"d":"1.46"},{"v":1.27318888422215,"d":"1.27"},{"v":0.348446466463173,"d":"0.35"},{"v":0.894426373872501,"d":"0.89"},{"v":0.992494965706608,"d":"0.99"},"up","no"]
["MSTRG.5648","TXNDC11","ENST00000283033;ENST00000572732;ENST00000356957;ENST00000573174;ENST00000575591;ENST00000576969;ENST00000575349;ENST00000571882","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0045454(cell redox homeostasis);GO:0005515(protein binding);GO:0006457(protein folding);GO:0003756(protein disulfide isomerase activity);GO:0034976(response to endoplasmic reticulum stress);GO:0005623(cell);GO:0005623(cell)","NA","NA","NA","thioredoxin domain containing 11 [Source:HGNC Symbol;Acc:HGNC:28030]",{"v":6.29736825931966,"d":"6.30"},{"v":5.54184788490214,"d":"5.54"},{"v":1.1363300455207,"d":"1.14"},{"v":0.184381924525691,"d":"0.18"},{"v":0.896719798835752,"d":"0.90"},{"v":0.993380427728664,"d":"0.99"},"up","no"]
["ENSG00000221994","ZNF630","ENST00000442455;ENST00000428686","GO:0003676(nucleic acid binding);GO:0006355(regulation of transcription, DNA-templated);GO:0005622(intracellular);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding)","NA","NA","NA","zinc finger protein 630 [Source:HGNC Symbol;Acc:HGNC:28855]",{"v":0.303244019314472,"d":"0.30"},{"v":0.269937335963003,"d":"0.27"},{"v":1.12338672319132,"d":"1.12"},{"v":0.167854657558063,"d":"0.17"},{"v":0.898827860858076,"d":"0.90"},{"v":0.993538480859177,"d":"0.99"},"up","no"]
["ENSG00000196247","ZNF107","ENST00000344930;ENST00000620827;ENST00000395391;ENST00000423627;ENST00000613690;ENST00000360117","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0003674(molecular_function);GO:0008150(biological_process);GO:0005575(cellular_component);GO:0005622(intracellular);GO:0005622(intracellular)","NA","NA","NA","zinc finger protein 107 [Source:HGNC Symbol;Acc:HGNC:12887]",{"v":1.02503835534767,"d":"1.03"},{"v":0.901581525830773,"d":"0.90"},{"v":1.13693362827409,"d":"1.14"},{"v":0.185148035272612,"d":"0.19"},{"v":0.899280838440122,"d":"0.90"},{"v":0.993538480859177,"d":"0.99"},"up","no"]
["ENSG00000166343","MSS51","ENST00000299432","GO:0046872(metal ion binding);GO:0035176(social behavior)","NA","NA","NA","MSS51 mitochondrial translational activator [Source:HGNC Symbol;Acc:HGNC:21000]",{"v":0.510813014857615,"d":"0.51"},{"v":0.386461742055303,"d":"0.39"},{"v":1.32176864944245,"d":"1.32"},{"v":0.402469682511046,"d":"0.40"},{"v":0.901097449728149,"d":"0.90"},{"v":0.993538480859177,"d":"0.99"},"up","no"]
["ENSG00000198000","NOL8","ENST00000442668;ENST00000535387;ENST00000543260;ENST00000535807;ENST00000358855;ENST00000535649;ENST00000421075;ENST00000536593;ENST00000545558;ENST00000538802;ENST00000544321;ENST00000542053;ENST00000477862;ENST00000542573;ENST00000463593;ENST00000432670;ENST00000360868;ENST00000544867;ENST00000543985;ENST00000545444;ENST00000482475;ENST00000434228;ENST00000445919","GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005730(nucleolus);GO:0006364(rRNA processing);GO:0005515(protein binding);GO:1902570(protein localization to nucleolus);GO:1902570(protein localization to nucleolus)","NA","NA","NA","nucleolar protein 8 [Source:HGNC Symbol;Acc:HGNC:23387]",{"v":2.84067997653923,"d":"2.84"},{"v":2.22205360265641,"d":"2.22"},{"v":1.27840299313359,"d":"1.28"},{"v":0.354342691174156,"d":"0.35"},{"v":0.901244907153307,"d":"0.90"},{"v":0.993538480859177,"d":"0.99"},"up","no"]
["MSTRG.13662","SBDS","ENST00000246868;ENST00000617799;ENST00000490953","GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0005654(nucleoplasm);GO:0043022(ribosome binding);GO:0042254(ribosome biogenesis);GO:0005730(nucleolus);GO:0006364(rRNA processing);GO:0008017(microtubule binding);GO:0000922(spindle pole);GO:0005819(spindle);GO:0042256(mature ribosome assembly);GO:0001833(inner cell mass cell proliferation);GO:0008283(cell proliferation);GO:0030282(bone mineralization);GO:0019843(rRNA binding);GO:0007052(mitotic spindle organization);GO:0030595(leukocyte chemotaxis);GO:0048539(bone marrow development);GO:0048539(bone marrow development)","03008(Ribosome biogenesis in eukaryotes);03008(Ribosome biogenesis in eukaryotes)","K14574","NA","SBDS, ribosome maturation factor [Source:HGNC Symbol;Acc:HGNC:19440]",{"v":8.32726375,"d":"8.33"},{"v":7.30277383545035,"d":"7.30"},{"v":1.14028777799148,"d":"1.14"},{"v":0.189397967799807,"d":"0.19"},{"v":0.903561330138565,"d":"0.90"},{"v":0.993953511711397,"d":"0.99"},"up","no"]
["ENSG00000075945","KIFAP3","ENST00000361580;ENST00000367765;ENST00000490550;ENST00000538366","GO:0005871(kinesin complex);GO:0005515(protein binding);GO:0019894(kinesin binding);GO:0035735(intraciliary transport involved in cilium assembly);GO:0005929(cilium);GO:0097542(ciliary tip);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0006890(retrograde vesicle-mediated transport, Golgi to ER);GO:0007018(microtubule-based movement);GO:0019886(antigen processing and presentation of exogenous peptide antigen via MHC class II);GO:0005783(endoplasmic reticulum);GO:0007165(signal transduction);GO:0006461(protein complex assembly);GO:0005876(spindle microtubule);GO:0015630(microtubule cytoskeleton);GO:0005813(centrosome);GO:0072383(plus-end-directed vesicle transport along microtubule);GO:0016939(kinesin II complex);GO:0007017(microtubule-based process);GO:0000794(condensed nuclear chromosome);GO:0008104(protein localization);GO:0008285(negative regulation of cell proliferation);GO:0043066(negative regulation of apoptotic process);GO:0046587(positive regulation of calcium-dependent cell-cell adhesion);GO:0005794(Golgi apparatus);GO:0005930(axoneme);GO:0030990(intraciliary transport particle);GO:0032391(photoreceptor connecting cilium);GO:0036064(ciliary basal body);GO:1990075(periciliary membrane compartment);GO:1990075(periciliary membrane compartment)","NA","NA","NA","kinesin associated protein 3 [Source:HGNC Symbol;Acc:HGNC:17060]",{"v":2.48986370349538,"d":"2.49"},{"v":2.18925716432302,"d":"2.19"},{"v":1.13730983461932,"d":"1.14"},{"v":0.185625337762363,"d":"0.19"},{"v":0.905121627786075,"d":"0.91"},{"v":0.993953511711397,"d":"0.99"},"up","no"]
["ENSG00000140876","NUDT7","ENST00000563839;ENST00000268533;ENST00000437314;ENST00000568787;ENST00000613075;ENST00000564085","GO:0003723(RNA binding);GO:0046872(metal ion binding);GO:0000287(magnesium ion binding);GO:0016787(hydrolase activity);GO:0016818(hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides);GO:0030145(manganese ion binding);GO:0005777(peroxisome);GO:0003674(molecular_function);GO:0008150(biological_process);GO:0005102(receptor binding);GO:0009062(fatty acid catabolic process);GO:0005782(peroxisomal matrix);GO:0009132(nucleoside diphosphate metabolic process);GO:0016289(CoA hydrolase activity);GO:0003986(acetyl-CoA hydrolase activity);GO:0030515(snoRNA binding);GO:0015938(coenzyme A catabolic process);GO:0046356(acetyl-CoA catabolic process);GO:0050873(brown fat cell differentiation);GO:0050873(brown fat cell differentiation)","04146(Peroxisome);04146(Peroxisome)","K17879","EC:3.6.1.-","nudix hydrolase 7 [Source:HGNC Symbol;Acc:HGNC:8054]",{"v":0.590625009157509,"d":"0.59"},{"v":0.469789415750916,"d":"0.47"},{"v":1.25721225160735,"d":"1.26"},{"v":0.330228236465845,"d":"0.33"},{"v":0.905397774546057,"d":"0.91"},{"v":0.993953511711397,"d":"0.99"},"up","no"]
["MSTRG.13187","QRSL1","ENST00000369046;ENST00000369044","GO:0006412(translation);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0005739(mitochondrion);GO:0016874(ligase activity);GO:0032543(mitochondrial translation);GO:0050567(glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity);GO:0070681(glutaminyl-tRNAGln biosynthesis via transamidation);GO:0030956(glutamyl-tRNA(Gln) amidotransferase complex);GO:0004040(amidase activity);GO:0031647(regulation of protein stability);GO:0031647(regulation of protein stability)","00970(Aminoacyl-tRNA biosynthesis);00970(Aminoacyl-tRNA biosynthesis)","K02433","EC:6.3.5.6;EC:6.3.5.7","glutaminyl-tRNA synthase (glutamine-hydrolyzing)-like 1 [Source:HGNC Symbol;Acc:HGNC:21020]",{"v":2.58600628901522,"d":"2.59"},{"v":2.03276069026224,"d":"2.03"},{"v":1.27216464850154,"d":"1.27"},{"v":0.347285401915103,"d":"0.35"},{"v":0.907527209184502,"d":"0.91"},{"v":0.994823707137942,"d":"0.99"},"up","no"]
["ENSG00000167384","ZNF180","ENST00000590088;ENST00000221327;ENST00000585514;ENST00000592529;ENST00000586637;ENST00000592095;ENST00000591064","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0005622(intracellular);GO:0005515(protein binding);GO:0005515(protein binding)","NA","NA","NA","zinc finger protein 180 [Source:HGNC Symbol;Acc:HGNC:12970]",{"v":0.443406956512649,"d":"0.44"},{"v":0.348723538155969,"d":"0.35"},{"v":1.27151427419371,"d":"1.27"},{"v":0.346547658011412,"d":"0.35"},{"v":0.908311144066789,"d":"0.91"},{"v":0.994823707137942,"d":"0.99"},"up","no"]
["ENSG00000214900","LINC01588","ENST00000554129;ENST00000533506;ENST00000557142;ENST00000553463;ENST00000530176;ENST00000529902;ENST00000556019;ENST00000556913;ENST00000528300;ENST00000399206;ENST00000635379;ENST00000553914;ENST00000556434;ENST00000623502","NA","NA","NA","NA","long intergenic non-protein coding RNA 1588 [Source:HGNC Symbol;Acc:HGNC:27503]",{"v":0.211201371943372,"d":"0.21"},{"v":0.18460923477613,"d":"0.18"},{"v":1.1440455413809,"d":"1.14"},{"v":0.194144483074913,"d":"0.19"},{"v":0.909992426330622,"d":"0.91"},{"v":0.994823707137942,"d":"0.99"},"up","no"]
["MSTRG.12144","AGGF1","ENST00000312916;ENST00000503538","GO:0003676(nucleic acid binding);GO:0005737(cytoplasm);GO:0007155(cell adhesion);GO:0005576(extracellular region);GO:0007275(multicellular organism development);GO:0048471(perinuclear region of cytoplasm);GO:0030154(cell differentiation);GO:0005515(protein binding);GO:0001525(angiogenesis);GO:0045766(positive regulation of angiogenesis);GO:0001938(positive regulation of endothelial cell proliferation);GO:0001570(vasculogenesis);GO:0001570(vasculogenesis)","NA","NA","NA","angiogenic factor with G-patch and FHA domains 1 [Source:HGNC Symbol;Acc:HGNC:24684]",{"v":5.54840707424272,"d":"5.55"},{"v":4.37074358820036,"d":"4.37"},{"v":1.26944236427451,"d":"1.27"},{"v":0.344194894660144,"d":"0.34"},{"v":0.910687121993514,"d":"0.91"},{"v":0.995042858005423,"d":"1.00"},"up","no"]
["ENSG00000196507","TCEAL3","ENST00000477014;ENST00000372627;ENST00000372628;ENST00000243286","GO:0005634(nucleus);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0050699(WW domain binding);GO:0050699(WW domain binding)","NA","NA","NA","transcription elongation factor A like 3 [Source:HGNC Symbol;Acc:HGNC:28247]",{"v":0.919530016052061,"d":"0.92"},{"v":0.812058078958785,"d":"0.81"},{"v":1.13234513623838,"d":"1.13"},{"v":0.179313755385711,"d":"0.18"},{"v":0.912298597631673,"d":"0.91"},{"v":0.995106578255826,"d":"1.00"},"up","no"]
["ENSG00000163608","NEPRO","ENST00000473284;ENST00000314400;ENST00000474311;ENST00000472705;ENST00000464816;ENST00000461381;ENST00000460410;ENST00000494891;ENST00000462295;ENST00000496340;ENST00000486271;ENST00000472166;ENST00000472762;ENST00000472637;ENST00000482229","GO:0005634(nucleus);GO:0007275(multicellular organism development);GO:0005730(nucleolus);GO:0045665(negative regulation of neuron differentiation);GO:0045747(positive regulation of Notch signaling pathway);GO:0045747(positive regulation of Notch signaling pathway)","NA","NA","NA","nucleolus and neural progenitor protein [Source:HGNC Symbol;Acc:HGNC:24496]",{"v":1.59137013720357,"d":"1.59"},{"v":1.38340829180782,"d":"1.38"},{"v":1.15032571846449,"d":"1.15"},{"v":0.20204242280318,"d":"0.20"},{"v":0.91391888622636,"d":"0.91"},{"v":0.995555592651727,"d":"1.00"},"up","no"]
["MSTRG.15063","GFI1B","ENST00000636137;ENST00000372122;ENST00000636263;ENST00000372123","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0016569(covalent chromatin modification);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0007275(multicellular organism development);GO:0030097(hemopoiesis);GO:0051569(regulation of histone H3-K4 methylation);GO:0005667(transcription factor complex);GO:0016363(nuclear matrix);GO:0006366(transcription from RNA polymerase II promoter);GO:0001085(RNA polymerase II transcription factor binding);GO:0008283(cell proliferation);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0000122(negative regulation of transcription from RNA polymerase II promoter)","NA","NA","NA","growth factor independent 1B transcriptional repressor [Source:HGNC Symbol;Acc:HGNC:4238]",{"v":6.2092906559973,"d":"6.21"},{"v":5.4052500148248,"d":"5.41"},{"v":1.14875179482305,"d":"1.15"},{"v":0.200067115599436,"d":"0.20"},{"v":0.914779516433428,"d":"0.91"},{"v":0.995555592651727,"d":"1.00"},"up","no"]
["ENSG00000099256","PRTFDC1","ENST00000320152;ENST00000376378;ENST00000376376","GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0009116(nucleoside metabolic process);GO:0042803(protein homodimerization activity);GO:0005515(protein binding);GO:0000287(magnesium ion binding);GO:0006166(purine ribonucleoside salvage);GO:0006166(purine ribonucleoside salvage)","NA","NA","NA","phosphoribosyl transferase domain containing 1 [Source:HGNC Symbol;Acc:HGNC:23333]",{"v":0.465675225418635,"d":"0.47"},{"v":0.402933520395019,"d":"0.40"},{"v":1.15571229954288,"d":"1.16"},{"v":0.208782301228711,"d":"0.21"},{"v":0.916593227807568,"d":"0.92"},{"v":0.995555592651727,"d":"1.00"},"up","no"]
["MSTRG.9920","U2AF1L5","ENST00000636177;ENST00000610664;ENST00000624739;ENST00000619610;ENST00000637320;ENST00000636403;ENST00000637031;ENST00000636923;ENST00000620065;ENST00000639996;ENST00000623375","GO:0003723(RNA binding);GO:0046872(metal ion binding);GO:0000398(mRNA splicing, via spliceosome);GO:0089701(U2AF);GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0016607(nuclear speck);GO:0016607(nuclear speck)","03040(Spliceosome);05131(Shigellosis);05131(Shigellosis)","K12836","NA","U2 small nuclear RNA auxiliary factor 1 like 5 [Source:HGNC Symbol;Acc:HGNC:51830]",{"v":1.99568665482507,"d":"2.00"},{"v":1.73687262946308,"d":"1.74"},{"v":1.14901151700571,"d":"1.15"},{"v":0.200393258770581,"d":"0.20"},{"v":0.916831100301667,"d":"0.92"},{"v":0.995555592651727,"d":"1.00"},"up","no"]
["MSTRG.10604","PPP6R2","ENST00000395744;ENST00000612753;ENST00000401672;ENST00000395741;ENST00000359139;ENST00000470046;ENST00000427222;ENST00000216061;ENST00000473283","GO:0005737(cytoplasm);GO:0043231(intracellular membrane-bounded organelle);GO:0005829(cytosol);GO:0005515(protein binding);GO:0005515(protein binding)","NA","NA","NA","protein phosphatase 6 regulatory subunit 2 [Source:HGNC Symbol;Acc:HGNC:19253]",{"v":6.98139153841839,"d":"6.98"},{"v":5.52381097812675,"d":"5.52"},{"v":1.26387227333871,"d":"1.26"},{"v":0.337850672429818,"d":"0.34"},{"v":0.918464832760406,"d":"0.92"},{"v":0.995811044986144,"d":"1.00"},"up","no"]
["MSTRG.10730","NKIRAS1","ENST00000388759;ENST00000443659;ENST00000425478;ENST00000437230;ENST00000421515;ENST00000412028","GO:0005737(cytoplasm);GO:0005525(GTP binding);GO:0016020(membrane);GO:0000166(nucleotide binding);GO:0007165(signal transduction);GO:0003924(GTPase activity);GO:0005575(cellular_component);GO:0007249(I-kappaB kinase/NF-kappaB signaling);GO:0007249(I-kappaB kinase/NF-kappaB signaling)","NA","NA","NA","NFKB inhibitor interacting Ras like 1 [Source:HGNC Symbol;Acc:HGNC:17899]",{"v":0.582520814857472,"d":"0.58"},{"v":0.513922514252807,"d":"0.51"},{"v":1.13347985095457,"d":"1.13"},{"v":0.180758745568085,"d":"0.18"},{"v":0.91999400212865,"d":"0.92"},{"v":0.996121725596076,"d":"1.00"},"up","no"]
["ENSG00000124067","SLC12A4","ENST00000316341;ENST00000576462;ENST00000537830;ENST00000575857;ENST00000574665;ENST00000541864;ENST00000572476;ENST00000573023;ENST00000572766;ENST00000422611;ENST00000572010;ENST00000576513;ENST00000573702;ENST00000570802;ENST00000576616","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005215(transporter activity);GO:0055085(transmembrane transport);GO:0006811(ion transport);GO:0005765(lysosomal membrane);GO:0015293(symporter activity);GO:0006813(potassium ion transport);GO:0071805(potassium ion transmembrane transport);GO:1902476(chloride transmembrane transport);GO:0015377(cation:chloride symporter activity);GO:0015379(potassium:chloride symporter activity);GO:0005886(plasma membrane);GO:0022820(potassium ion symporter activity);GO:0006821(chloride transport);GO:0005887(integral component of plasma membrane);GO:0007268(chemical synaptic transmission);GO:0019901(protein kinase binding);GO:0006884(cell volume homeostasis);GO:0006884(cell volume homeostasis)","NA","NA","NA","solute carrier family 12 member 4 [Source:HGNC Symbol;Acc:HGNC:10913]",{"v":1.69482114666185,"d":"1.69"},{"v":1.33769959207038,"d":"1.34"},{"v":1.26696693092262,"d":"1.27"},{"v":0.341378869217035,"d":"0.34"},{"v":0.921692094193035,"d":"0.92"},{"v":0.996121725596076,"d":"1.00"},"up","no"]
["ENSG00000161298","ZNF382","ENST00000435416;ENST00000292928;ENST00000460384;ENST00000460670;ENST00000439428;ENST00000463910;ENST00000590785","GO:0003676(nucleic acid binding);GO:0006355(regulation of transcription, DNA-templated);GO:0005622(intracellular);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0044212(transcription regulatory region DNA binding);GO:0044212(transcription regulatory region DNA binding)","NA","NA","NA","zinc finger protein 382 [Source:HGNC Symbol;Acc:HGNC:17409]",{"v":0.197331776815692,"d":"0.20"},{"v":0.154471852359074,"d":"0.15"},{"v":1.27746106363112,"d":"1.28"},{"v":0.35327931921585,"d":"0.35"},{"v":0.923465724543213,"d":"0.92"},{"v":0.996121725596076,"d":"1.00"},"up","no"]
["MSTRG.60","ACAP3","ENST00000354700;ENST00000493992;ENST00000492936;ENST00000438966;ENST00000476572;ENST00000478065;ENST00000472541;ENST00000479108;ENST00000379037;ENST00000470659;ENST00000467278;ENST00000354980","GO:0046872(metal ion binding);GO:0043547(positive regulation of GTPase activity);GO:0005096(GTPase activator activity);GO:0005096(GTPase activator activity)","04144(Endocytosis);04144(Endocytosis)","K12489","NA","ArfGAP with coiled-coil, ankyrin repeat and PH domains 3 [Source:HGNC Symbol;Acc:HGNC:16754]",{"v":1.33009175706664,"d":"1.33"},{"v":1.15367102508798,"d":"1.15"},{"v":1.15292117782468,"d":"1.15"},{"v":0.20529388311232,"d":"0.21"},{"v":0.923767797685759,"d":"0.92"},{"v":0.996121725596076,"d":"1.00"},"up","no"]
["MSTRG.9305","STAT1","ENST00000392322;ENST00000392323;MSTRG.9305.4;ENST00000540176;ENST00000361099;ENST00000452281;ENST00000464072;ENST00000423282;ENST00000409465;ENST00000415035;ENST00000454414;ENST00000432058;ENST00000424722","GO:0005634(nucleus);GO:0006355(regulation of transcription, DNA-templated);GO:0007165(signal transduction);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0004871(signal transducer activity);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0005737(cytoplasm);GO:0005730(nucleolus);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0042803(protein homodimerization activity);GO:0005515(protein binding);GO:0006915(apoptotic process);GO:0048471(perinuclear region of cytoplasm);GO:0045893(positive regulation of transcription, DNA-templated);GO:0030425(dendrite);GO:0042802(identical protein binding);GO:0051607(defense response to virus);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0030424(axon);GO:0001047(core promoter binding);GO:0045296(cadherin binding);GO:0071346(cellular response to interferon-gamma);GO:0016032(viral process);GO:0003690(double-stranded DNA binding);GO:0042981(regulation of apoptotic process);GO:0035722(interleukin-12-mediated signaling pathway);GO:0019899(enzyme binding);GO:0000790(nuclear chromatin);GO:0070491(repressing transcription factor binding);GO:0001937(negative regulation of endothelial cell proliferation);GO:0016525(negative regulation of angiogenesis);GO:0060333(interferon-gamma-mediated signaling pathway);GO:0060334(regulation of interferon-gamma-mediated signaling pathway);GO:0043124(negative regulation of I-kappaB kinase/NF-kappaB signaling);GO:0005164(tumor necrosis factor receptor binding);GO:0033209(tumor necrosis factor-mediated signaling pathway);GO:0060337(type I interferon signaling pathway);GO:0048661(positive regulation of smooth muscle cell proliferation);GO:0035456(response to interferon-beta);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:0051591(response to cAMP);GO:0035257(nuclear hormone receptor binding);GO:0002053(positive regulation of mesenchymal cell proliferation);GO:0072162(metanephric mesenchymal cell differentiation);GO:0000983(transcription factor activity, RNA polymerase II core promoter sequence-specific);GO:0034097(response to cytokine);GO:0060338(regulation of type I interferon-mediated signaling pathway);GO:0035458(cellular response to interferon-beta);GO:0045648(positive regulation of erythrocyte differentiation);GO:0000979(RNA polymerase II core promoter sequence-specific DNA binding);GO:0010742(macrophage derived foam cell differentiation);GO:0007259(JAK-STAT cascade);GO:0003340(negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis);GO:0008015(blood circulation);GO:0043434(response to peptide hormone);GO:0046725(negative regulation by virus of viral protein levels in host cell);GO:0061326(renal tubule development);GO:0072136(metanephric mesenchymal cell proliferation involved in metanephros development);GO:0072308(negative regulation of metanephric nephron tubule epithelial cell differentiation);GO:0072308(negative regulation of metanephric nephron tubule epithelial cell differentiation)","04630(Jak-STAT signaling pathway);04217(Necroptosis);04620(Toll-like receptor signaling pathway);04621(NOD-like receptor signaling pathway);04658(Th1 and Th2 cell differentiation);04659(Th17 cell differentiation);04062(Chemokine signaling pathway);04917(Prolactin signaling pathway);04919(Thyroid hormone signaling pathway);04380(Osteoclast differentiation);05200(Pathways in cancer);05212(Pancreatic cancer);05321(Inflammatiory bowel disease (IBD));04933(AGE-RAGE signaling pathway in diabetic complications);05152(Tuberculosis);05162(Measles);05164(Influenza A);05161(Hepatitis B);05160(Hepatitis C);05168(Herpes simplex infection);05167(Kaposi's sarcoma-associated herpesvirus infection);05165(Human papillomavirus infection);05145(Toxoplasmosis);05140(Leishmaniasis);05140(Leishmaniasis)","K11220","NA","signal transducer and activator of transcription 1 [Source:HGNC Symbol;Acc:HGNC:11362]",{"v":25.2786749261523,"d":"25.28"},{"v":20.0917692142739,"d":"20.09"},{"v":1.2581607252483,"d":"1.26"},{"v":0.331316232795342,"d":"0.33"},{"v":0.925060829778913,"d":"0.93"},{"v":0.996121725596076,"d":"1.00"},"up","no"]
["ENSG00000137124","ALDH1B1","ENST00000377698","GO:0043231(intracellular membrane-bounded organelle);GO:0005654(nucleoplasm);GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0005739(mitochondrion);GO:0008152(metabolic process);GO:0005759(mitochondrial matrix);GO:0004029(aldehyde dehydrogenase (NAD) activity);GO:0005975(carbohydrate metabolic process);GO:0006069(ethanol oxidation);GO:0051287(NAD binding);GO:0006068(ethanol catabolic process)","00010(Glycolysis / Gluconeogenesis);00053(Ascorbate and aldarate metabolism);00620(Pyruvate metabolism);00071(Fatty acid degradation);00561(Glycerolipid metabolism);00280(Valine, leucine and isoleucine degradation);00310(Lysine degradation);00330(Arginine and proline metabolism);00340(Histidine metabolism);00380(Tryptophan metabolism);00410(beta-Alanine metabolism)","K00128","EC:1.2.1.3","aldehyde dehydrogenase 1 family member B1 [Source:HGNC Symbol;Acc:HGNC:407]",{"v":1.33439219714739,"d":"1.33"},{"v":1.15979540158479,"d":"1.16"},{"v":1.15054103105084,"d":"1.15"},{"v":0.202312434442522,"d":"0.20"},{"v":0.926199071535834,"d":"0.93"},{"v":0.996121725596076,"d":"1.00"},"up","no"]
["MSTRG.687","GBP1","ENST00000459831;ENST00000370473;ENST00000493139;ENST00000495131;ENST00000469194;ENST00000479889;ENST00000468959;ENST00000484970","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005525(GTP binding);GO:0000166(nucleotide binding);GO:0016787(hydrolase activity);GO:0003924(GTPase activity);GO:0005794(Golgi apparatus);GO:0003779(actin binding);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0005576(extracellular region);GO:0000139(Golgi membrane);GO:0002376(immune system process);GO:0042802(identical protein binding);GO:0051607(defense response to virus);GO:0005515(protein binding);GO:0019899(enzyme binding);GO:0060333(interferon-gamma-mediated signaling pathway);GO:0070373(negative regulation of ERK1 and ERK2 cascade);GO:1900025(negative regulation of substrate adhesion-dependent cell spreading);GO:1903076(regulation of protein localization to plasma membrane);GO:0042803(protein homodimerization activity);GO:0051260(protein homooligomerization);GO:0051879(Hsp90 protein binding);GO:0019003(GDP binding);GO:1903077(negative regulation of protein localization to plasma membrane);GO:0050860(negative regulation of T cell receptor signaling pathway);GO:0019955(cytokine binding);GO:1900041(negative regulation of interleukin-2 secretion);GO:0030507(spectrin binding);GO:0050848(regulation of calcium-mediated signaling);GO:0050848(regulation of calcium-mediated signaling)","04621(NOD-like receptor signaling pathway);04621(NOD-like receptor signaling pathway)","K20899","NA","guanylate binding protein 1 [Source:HGNC Symbol;Acc:HGNC:4182]",{"v":12.8635120328526,"d":"12.86"},{"v":10.2373743008814,"d":"10.24"},{"v":1.25652453986615,"d":"1.26"},{"v":0.329438847261138,"d":"0.33"},{"v":0.927496890061923,"d":"0.93"},{"v":0.996121725596076,"d":"1.00"},"up","no"]
["MSTRG.5817","HIRIP3","ENST00000279392;ENST00000564026;ENST00000563053;ENST00000568880;ENST00000565996;ENST00000563680","GO:0005634(nucleus);GO:0005730(nucleolus);GO:0005515(protein binding);GO:0006333(chromatin assembly or disassembly);GO:0006333(chromatin assembly or disassembly)","NA","NA","NA","HIRA interacting protein 3 [Source:HGNC Symbol;Acc:HGNC:4917]",{"v":1.53211277308573,"d":"1.53"},{"v":1.32329676240142,"d":"1.32"},{"v":1.15779983494055,"d":"1.16"},{"v":0.211385856004473,"d":"0.21"},{"v":0.928086842123512,"d":"0.93"},{"v":0.996121725596076,"d":"1.00"},"up","no"]
["MSTRG.15035","USP20","ENST00000315480;ENST00000372429;ENST00000472108;ENST00000494971;ENST00000491053;ENST00000358355;ENST00000496927;ENST00000491731","GO:0005737(cytoplasm);GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0004843(thiol-dependent ubiquitin-specific protease activity);GO:0016579(protein deubiquitination);GO:0016787(hydrolase activity);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0008233(peptidase activity);GO:0008234(cysteine-type peptidase activity);GO:0006508(proteolysis);GO:0006511(ubiquitin-dependent protein catabolic process);GO:0036459(thiol-dependent ubiquitinyl hydrolase activity);GO:0048471(perinuclear region of cytoplasm);GO:0005813(centrosome);GO:0005815(microtubule organizing center);GO:0005829(cytosol);GO:0006897(endocytosis);GO:0070536(protein K63-linked deubiquitination);GO:0071108(protein K48-linked deubiquitination);GO:0001664(G-protein coupled receptor binding);GO:0008277(regulation of G-protein coupled receptor protein signaling pathway);GO:0004197(cysteine-type endopeptidase activity);GO:0004197(cysteine-type endopeptidase activity)","NA","NA","NA","ubiquitin specific peptidase 20 [Source:HGNC Symbol;Acc:HGNC:12619]",{"v":6.43670219561674,"d":"6.44"},{"v":5.13068967379098,"d":"5.13"},{"v":1.25454911617384,"d":"1.25"},{"v":0.327168954025937,"d":"0.33"},{"v":0.928983062269361,"d":"0.93"},{"v":0.996121725596076,"d":"1.00"},"up","no"]
["ENSG00000104884","ERCC2","ENST00000586441;ENST00000391941;ENST00000591309;ENST00000391944;ENST00000391945;ENST00000586737;ENST00000586856;ENST00000588652;ENST00000391942","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0016787(hydrolase activity);GO:0003677(DNA binding);GO:0004003(ATP-dependent DNA helicase activity);GO:0004386(helicase activity);GO:0008026(ATP-dependent helicase activity);GO:0016818(hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides);GO:0006139(nucleobase-containing compound metabolic process);GO:0032508(DNA duplex unwinding);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0006468(protein phosphorylation);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0006281(DNA repair);GO:0006974(cellular response to DNA damage stimulus);GO:0006915(apoptotic process);GO:0006289(nucleotide-excision repair);GO:0051536(iron-sulfur cluster binding);GO:0051539(4 iron, 4 sulfur cluster binding);GO:0045893(positive regulation of transcription, DNA-templated);GO:0005819(spindle);GO:0007059(chromosome segregation);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0006366(transcription from RNA polymerase II promoter);GO:0016032(viral process);GO:0008022(protein C-terminus binding);GO:0047485(protein N-terminus binding);GO:0006979(response to oxidative stress);GO:0006368(transcription elongation from RNA polymerase II promoter);GO:0006370(7-methylguanosine mRNA capping);GO:0006367(transcription initiation from RNA polymerase II promoter);GO:0004672(protein kinase activity);GO:0006361(transcription initiation from RNA polymerase I promoter);GO:0006362(transcription elongation from RNA polymerase I promoter);GO:0006363(termination of RNA polymerase I transcription);GO:1901990(regulation of mitotic cell cycle phase transition);GO:0008094(DNA-dependent ATPase activity);GO:0006283(transcription-coupled nucleotide-excision repair);GO:0005669(transcription factor TFIID complex);GO:0071817(MMXD complex);GO:0008353(RNA polymerase II carboxy-terminal domain kinase activity);GO:0006293(nucleotide-excision repair, preincision complex stabilization);GO:0006295(nucleotide-excision repair, DNA incision, 3'-to lesion);GO:0006296(nucleotide-excision repair, DNA incision, 5'-to lesion);GO:0033683(nucleotide-excision repair, DNA incision);GO:0070911(global genome nucleotide-excision repair);GO:0000717(nucleotide-excision repair, DNA duplex unwinding);GO:0006294(nucleotide-excision repair, preincision complex assembly);GO:0019907(cyclin-dependent protein kinase activating kinase holoenzyme complex);GO:0043139(5'-3' DNA helicase activity);GO:0009650(UV protection);GO:0035315(hair cell differentiation);GO:0005675(holo TFIIH complex);GO:0001666(response to hypoxia);GO:0001701(in utero embryonic development);GO:0007568(aging);GO:0008283(cell proliferation);GO:0009411(response to UV);GO:0009791(post-embryonic development);GO:0021510(spinal cord development);GO:0022405(hair cycle process);GO:0030198(extracellular matrix organization);GO:0030282(bone mineralization);GO:0032289(central nervous system myelin formation);GO:0035264(multicellular organism growth);GO:0040016(embryonic cleavage);GO:0043249(erythrocyte maturation);GO:0043388(positive regulation of DNA binding);GO:0043588(skin development);GO:0048568(embryonic organ development);GO:0048820(hair follicle maturation);GO:0060218(hematopoietic stem cell differentiation);GO:0000439(core TFIIH complex);GO:0000439(core TFIIH complex)","03022(Basal transcription factors);03420(Nucleotide excision repair);03420(Nucleotide excision repair)","K10844","EC:3.6.4.12","ERCC excision repair 2, TFIIH core complex helicase subunit [Source:HGNC Symbol;Acc:HGNC:3434]",{"v":1.12991722356589,"d":"1.13"},{"v":0.973388964031008,"d":"0.97"},{"v":1.16080751407604,"d":"1.16"},{"v":0.215128763322567,"d":"0.22"},{"v":0.930526796436587,"d":"0.93"},{"v":0.996121725596076,"d":"1.00"},"up","no"]
["ENSG00000134444","KIAA1468","ENST00000398130;ENST00000587198;ENST00000587714;ENST00000588446;ENST00000587764;ENST00000593217;ENST00000592479;ENST00000590713;ENST00000256858","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016021(integral component of membrane)","NA","NA","NA","KIAA1468 [Source:HGNC Symbol;Acc:HGNC:29289]",{"v":2.66396781600193,"d":"2.66"},{"v":2.30180484564405,"d":"2.30"},{"v":1.15733869491292,"d":"1.16"},{"v":0.210811130620888,"d":"0.21"},{"v":0.931270288677824,"d":"0.93"},{"v":0.996121725596076,"d":"1.00"},"up","no"]
["ENSG00000162542","TMCO4","ENST00000294543;ENST00000496528;ENST00000489814;ENST00000375127;ENST00000462171;ENST00000488449;ENST00000489135","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016021(integral component of membrane)","NA","NA","NA","transmembrane and coiled-coil domains 4 [Source:HGNC Symbol;Acc:HGNC:27393]",{"v":2.12079241736557,"d":"2.12"},{"v":1.69010118500247,"d":"1.69"},{"v":1.25483162557659,"d":"1.25"},{"v":0.327493795058856,"d":"0.33"},{"v":0.932864883892231,"d":"0.93"},{"v":0.996121725596076,"d":"1.00"},"up","no"]
["ENSG00000178188","SH2B1","ENST00000337120;ENST00000359285;ENST00000545570;ENST00000568868;ENST00000569471;ENST00000561629;ENST00000538342;ENST00000566176;ENST00000322610;ENST00000563674;ENST00000567536","GO:0005622(intracellular);GO:0035556(intracellular signal transduction);GO:0007165(signal transduction);GO:0004871(signal transducer activity);GO:0035591(signaling adaptor activity);GO:0009967(positive regulation of signal transduction);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0030032(lamellipodium assembly);GO:0045840(positive regulation of mitotic nuclear division);GO:2000278(regulation of DNA biosynthetic process);GO:0005515(protein binding);GO:0005829(cytosol);GO:0007596(blood coagulation);GO:0007596(blood coagulation)","04722(Neurotrophin signaling pathway);04722(Neurotrophin signaling pathway)","K12459","NA","SH2B adaptor protein 1 [Source:HGNC Symbol;Acc:HGNC:30417]",{"v":2.55351705976207,"d":"2.55"},{"v":2.0357852986704,"d":"2.04"},{"v":1.25431550244017,"d":"1.25"},{"v":0.326900280002213,"d":"0.33"},{"v":0.934454407466699,"d":"0.93"},{"v":0.996121725596076,"d":"1.00"},"up","no"]
["ENSG00000168096","ANKS3","ENST00000593120;ENST00000614075;ENST00000589035;ENST00000586159;ENST00000590803;ENST00000591185;ENST00000590689;ENST00000446014;ENST00000592711;ENST00000588398;ENST00000585773;ENST00000592698;ENST00000591653;ENST00000304283;ENST00000586605;ENST00000590730;ENST00000586632;ENST00000592840;ENST00000592190","GO:0005515(protein binding);GO:0005515(protein binding)","NA","NA","NA","ankyrin repeat and sterile alpha motif domain containing 3 [Source:HGNC Symbol;Acc:HGNC:29422]",{"v":0.363382852058973,"d":"0.36"},{"v":0.316487506100661,"d":"0.32"},{"v":1.14817439884466,"d":"1.15"},{"v":0.199341792918639,"d":"0.20"},{"v":0.935241194486106,"d":"0.94"},{"v":0.996121725596076,"d":"1.00"},"up","no"]
["MSTRG.1939","PSD","ENST00000611678;ENST00000020673;ENST00000461698;ENST00000473507;ENST00000492902;ENST00000479172","GO:0016020(membrane);GO:0005886(plasma membrane);GO:0043547(positive regulation of GTPase activity);GO:0042995(cell projection);GO:0005515(protein binding);GO:0004871(signal transducer activity);GO:0007165(signal transduction);GO:0005543(phospholipid binding);GO:0005086(ARF guanyl-nucleotide exchange factor activity);GO:0032012(regulation of ARF protein signal transduction);GO:0005085(guanyl-nucleotide exchange factor activity);GO:0031175(neuron projection development);GO:0014069(postsynaptic density);GO:0032154(cleavage furrow);GO:0032587(ruffle membrane);GO:0043197(dendritic spine);GO:0098999(extrinsic component of postsynaptic endosome membrane);GO:0098999(extrinsic component of postsynaptic endosome membrane)","04144(Endocytosis);04144(Endocytosis)","K12494","NA","pleckstrin and Sec7 domain containing [Source:HGNC Symbol;Acc:HGNC:9507]",{"v":0.349527118964973,"d":"0.35"},{"v":0.302845755916693,"d":"0.30"},{"v":1.15414237160755,"d":"1.15"},{"v":0.206821201576946,"d":"0.21"},{"v":0.936539930911504,"d":"0.94"},{"v":0.996121725596076,"d":"1.00"},"up","no"]
["MSTRG.12496","CNOT8","MSTRG.12496.6;ENST00000517876;ENST00000285896;ENST00000523270;ENST00000517568;ENST00000522458;ENST00000519903;ENST00000522644;ENST00000522139;ENST00000521174;ENST00000524105;ENST00000519394;ENST00000521583;ENST00000403027;ENST00000521450;ENST00000519430;ENST00000520671;ENST00000521402;ENST00000520472;ENST00000519404;ENST00000518782;ENST00000518775;ENST00000518028;ENST00000519211","GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0016787(hydrolase activity);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0090305(nucleic acid phosphodiester bond hydrolysis);GO:0005515(protein binding);GO:0004527(exonuclease activity);GO:0004518(nuclease activity);GO:0031047(gene silencing by RNA);GO:0006977(DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest);GO:0005829(cytosol);GO:0004535(poly(A)-specific ribonuclease activity);GO:0000289(nuclear-transcribed mRNA poly(A) tail shortening);GO:0006417(regulation of translation);GO:0061014(positive regulation of mRNA catabolic process);GO:0090503(RNA phosphodiester bond hydrolysis, exonucleolytic);GO:0030014(CCR4-NOT complex);GO:0030015(CCR4-NOT core complex);GO:0000932(P-body);GO:0008284(positive regulation of cell proliferation);GO:0008285(negative regulation of cell proliferation);GO:0005622(intracellular);GO:0035195(gene silencing by miRNA);GO:0000175(3'-5'-exoribonuclease activity);GO:0043928(exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay);GO:0043928(exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay)","03018(RNA degradation);03018(RNA degradation)","K12581","NA","CCR4-NOT transcription complex subunit 8 [Source:HGNC Symbol;Acc:HGNC:9207]",{"v":16.8931587173028,"d":"16.89"},{"v":14.5360372178117,"d":"14.54"},{"v":1.16215709028337,"d":"1.16"},{"v":0.216805092886103,"d":"0.22"},{"v":0.937205762701703,"d":"0.94"},{"v":0.996121725596076,"d":"1.00"},"up","no"]
["ENSG00000060982","BCAT1","ENST00000261192;ENST00000612790;ENST00000539282;ENST00000538118","GO:0005737(cytoplasm);GO:0016740(transferase activity);GO:0003824(catalytic activity);GO:0008152(metabolic process);GO:0008483(transaminase activity);GO:0008652(cellular amino acid biosynthetic process);GO:0004084(branched-chain-amino-acid transaminase activity);GO:0052654(L-leucine transaminase activity);GO:0052655(L-valine transaminase activity);GO:0052656(L-isoleucine transaminase activity);GO:0009081(branched-chain amino acid metabolic process);GO:0009082(branched-chain amino acid biosynthetic process);GO:0005739(mitochondrion);GO:0005829(cytosol);GO:0000082(G1/S transition of mitotic cell cycle);GO:0008283(cell proliferation);GO:0009083(branched-chain amino acid catabolic process);GO:0009098(leucine biosynthetic process);GO:0009099(valine biosynthetic process);GO:0042802(identical protein binding);GO:0042802(identical protein binding)","00270(Cysteine and methionine metabolism);00280(Valine, leucine and isoleucine degradation);00290(Valine, leucine and isoleucine biosynthesis);00770(Pantothenate and CoA biosynthesis);00770(Pantothenate and CoA biosynthesis)","K00826","EC:2.6.1.42","branched chain amino acid transaminase 1 [Source:HGNC Symbol;Acc:HGNC:976]",{"v":0.34386613970276,"d":"0.34"},{"v":0.27351844118896,"d":"0.27"},{"v":1.2571954498132,"d":"1.26"},{"v":0.330208955690432,"d":"0.33"},{"v":0.938547338648611,"d":"0.94"},{"v":0.996121725596076,"d":"1.00"},"up","no"]
["ENSG00000187091","PLCD1","ENST00000463876;ENST00000473834;ENST00000479619;ENST00000461445;ENST00000484829;ENST00000417185","GO:0046872(metal ion binding);GO:0016787(hydrolase activity);GO:0035556(intracellular signal transduction);GO:0005509(calcium ion binding);GO:0007165(signal transduction);GO:0006629(lipid metabolic process);GO:0016042(lipid catabolic process);GO:0004871(signal transducer activity);GO:0008081(phosphoric diester hydrolase activity);GO:0005886(plasma membrane);GO:0004435(phosphatidylinositol phospholipase C activity);GO:0070062(extracellular exosome);GO:0005546(phosphatidylinositol-4,5-bisphosphate binding);GO:0005737(cytoplasm);GO:0043647(inositol phosphate metabolic process);GO:0032794(GTPase activating protein binding);GO:0006644(phospholipid metabolic process);GO:0001786(phosphatidylserine binding);GO:0004629(phospholipase C activity);GO:0070300(phosphatidic acid binding);GO:1901981(phosphatidylinositol phosphate binding);GO:0001525(angiogenesis);GO:0042127(regulation of cell proliferation);GO:0060716(labyrinthine layer blood vessel development);GO:0005829(cytosol);GO:0005829(cytosol)","00562(Inositol phosphate metabolism);04020(Calcium signaling pathway);04070(Phosphatidylinositol signaling system);04919(Thyroid hormone signaling pathway);04933(AGE-RAGE signaling pathway in diabetic complications);04933(AGE-RAGE signaling pathway in diabetic complications)","K05857","EC:3.1.4.11","phospholipase C delta 1 [Source:HGNC Symbol;Acc:HGNC:9060]",{"v":2.58685025173853,"d":"2.59"},{"v":2.21766801205378,"d":"2.22"},{"v":1.16647317708427,"d":"1.17"},{"v":0.222153133098004,"d":"0.22"},{"v":0.939033109089688,"d":"0.94"},{"v":0.996121725596076,"d":"1.00"},"up","no"]
["MSTRG.6486","FLCN;PLD6;AC055811.2","ENST00000389169;ENST00000389168;ENST00000285071;ENST00000321560;ENST00000466317;ENST00000417064;ENST00000480316;ENST00000473853;ENST00000427497;ENST00000389171;ENST00000577591","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0043547(positive regulation of GTPase activity);GO:0005085(guanyl-nucleotide exchange factor activity);GO:0030496(midbody);GO:0005515(protein binding);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0001934(positive regulation of protein phosphorylation);GO:0043065(positive regulation of apoptotic process);GO:0010629(negative regulation of gene expression);GO:0045785(positive regulation of cell adhesion);GO:0030308(negative regulation of cell growth);GO:0030511(positive regulation of transforming growth factor beta receptor signaling pathway);GO:0032007(negative regulation of TOR signaling);GO:0007043(cell-cell junction assembly);GO:0032403(protein complex binding);GO:0030097(hemopoiesis);GO:0001701(in utero embryonic development);GO:0070373(negative regulation of ERK1 and ERK2 cascade);GO:0051898(negative regulation of protein kinase B signaling);GO:0001932(regulation of protein phosphorylation);GO:0030336(negative regulation of cell migration);GO:0032008(positive regulation of TOR signaling);GO:0032006(regulation of TOR signaling);GO:0032465(regulation of cytokinesis);GO:0044291(cell-cell contact zone);GO:0005764(lysosome);GO:0031929(TOR signaling);GO:0010508(positive regulation of autophagy);GO:0035024(negative regulation of Rho protein signal transduction);GO:1900181(negative regulation of protein localization to nucleus);GO:0035065(regulation of histone acetylation);GO:0010823(negative regulation of mitochondrion organization);GO:1901723(negative regulation of cell proliferation involved in kidney development);GO:2000506(negative regulation of energy homeostasis);GO:2000973(regulation of pro-B cell differentiation);GO:2001170(negative regulation of ATP biosynthetic process);GO:0005929(cilium);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0046872(metal ion binding);GO:0016787(hydrolase activity);GO:0003824(catalytic activity);GO:0006629(lipid metabolic process);GO:0016042(lipid catabolic process);GO:0005739(mitochondrion);GO:0042803(protein homodimerization activity);GO:0090305(nucleic acid phosphodiester bond hydrolysis);GO:0004519(endonuclease activity);GO:0004518(nuclease activity);GO:0051321(meiotic cell cycle);GO:0005741(mitochondrial outer membrane);GO:0030154(cell differentiation);GO:0007283(spermatogenesis);GO:0006654(phosphatidic acid biosynthetic process);GO:0008053(mitochondrial fusion);GO:0034587(piRNA metabolic process);GO:0043046(DNA methylation involved in gamete generation);GO:0007286(spermatid development);GO:0035755(cardiolipin hydrolase activity);GO:0010636(positive regulation of mitochondrial fusion);GO:0030719(P granule organization);GO:0005929(cilium)","04150(mTOR signaling pathway);05211(Renal cell carcinoma);05211(Renal cell carcinoma)","K09594","NA","folliculin [Source:HGNC Symbol;Acc:HGNC:27310];phospholipase D family member 6 [Source:HGNC Symbol;Acc:HGNC:30447]",{"v":1.60579195019311,"d":"1.61"},{"v":1.28647473817187,"d":"1.29"},{"v":1.24821102392963,"d":"1.25"},{"v":0.319861858431398,"d":"0.32"},{"v":0.940708266626311,"d":"0.94"},{"v":0.99636940156018,"d":"1.00"},"up","no"]
["MSTRG.7596","POLR2E","ENST00000615234;ENST00000589737;ENST00000586746;ENST00000612655;ENST00000586215;ENST00000585838;ENST00000619917;ENST00000591709;ENST00000590060;ENST00000586817;ENST00000215587;ENST00000591767;ENST00000592597","GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0003677(DNA binding);GO:0006351(transcription, DNA-templated);GO:0005515(protein binding);GO:0003899(DNA-directed 5'-3' RNA polymerase activity);GO:0005666(DNA-directed RNA polymerase III complex);GO:0005829(cytosol);GO:0006366(transcription from RNA polymerase II promoter);GO:0016032(viral process);GO:0045815(positive regulation of gene expression, epigenetic);GO:0006368(transcription elongation from RNA polymerase II promoter);GO:0006370(7-methylguanosine mRNA capping);GO:0050434(positive regulation of viral transcription);GO:0006367(transcription initiation from RNA polymerase II promoter);GO:0042795(snRNA transcription from RNA polymerase II promoter);GO:0001056(RNA polymerase III activity);GO:0006383(transcription from RNA polymerase III promoter);GO:0032481(positive regulation of type I interferon production);GO:0000398(mRNA splicing, via spliceosome);GO:0001054(RNA polymerase I activity);GO:0006361(transcription initiation from RNA polymerase I promoter);GO:0006362(transcription elongation from RNA polymerase I promoter);GO:0006363(termination of RNA polymerase I transcription);GO:0005736(DNA-directed RNA polymerase I complex);GO:0060964(regulation of gene silencing by miRNA);GO:0006283(transcription-coupled nucleotide-excision repair);GO:0008543(fibroblast growth factor receptor signaling pathway);GO:0016070(RNA metabolic process);GO:0035019(somatic stem cell population maintenance);GO:0005665(DNA-directed RNA polymerase II, core complex);GO:0001055(RNA polymerase II activity);GO:0001055(RNA polymerase II activity)","00230(Purine metabolism);00240(Pyrimidine metabolism);03020(RNA polymerase);04623(Cytosolic DNA-sensing pathway);05016(Huntington's disease);05169(Epstein-Barr virus infection);05169(Epstein-Barr virus infection)","K03013","NA","RNA polymerase II subunit E [Source:HGNC Symbol;Acc:HGNC:9192]",{"v":5.66119004110997,"d":"5.66"},{"v":4.86067873381295,"d":"4.86"},{"v":1.16469126044647,"d":"1.16"},{"v":0.219947572000785,"d":"0.22"},{"v":0.941538325379741,"d":"0.94"},{"v":0.996489349172959,"d":"1.00"},"up","no"]
["ENSG00000228409","CCT6P1","ENST00000442266;ENST00000434500","NA","NA","NA","NA","chaperonin containing TCP1 subunit 6 pseudogene 1 [Source:HGNC Symbol;Acc:HGNC:33094]",{"v":1.50114533053892,"d":"1.50"},{"v":1.28766433832335,"d":"1.29"},{"v":1.16578931780742,"d":"1.17"},{"v":0.221307087322441,"d":"0.22"},{"v":0.943339071922386,"d":"0.94"},{"v":0.996489349172959,"d":"1.00"},"up","no"]
["ENSG00000038210","PI4K2B","ENST00000264864","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0005886(plasma membrane);GO:0005829(cytosol);GO:0005768(endosome);GO:0004430(1-phosphatidylinositol 4-kinase activity);GO:0007030(Golgi organization);GO:0007032(endosome organization);GO:0046854(phosphatidylinositol phosphorylation);GO:0005802(trans-Golgi network);GO:0006661(phosphatidylinositol biosynthetic process)","00562(Inositol phosphate metabolism);04070(Phosphatidylinositol signaling system)","K13711","EC:2.7.1.67","phosphatidylinositol 4-kinase type 2 beta [Source:HGNC Symbol;Acc:HGNC:18215]",{"v":2.691616,"d":"2.69"},{"v":2.310763,"d":"2.31"},{"v":1.16481698902051,"d":"1.16"},{"v":0.220103302713891,"d":"0.22"},{"v":0.943821975167322,"d":"0.94"},{"v":0.996489349172959,"d":"1.00"},"up","no"]
["MSTRG.7926","TPM4","ENST00000344824;ENST00000300933;ENST00000588483;ENST00000588507;ENST00000586193;ENST00000590180;ENST00000592138;ENST00000587201;ENST00000591226;ENST00000588410;ENST00000586499;ENST00000591645;ENST00000589897;ENST00000592822","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0046872(metal ion binding);GO:0003779(actin binding);GO:0042803(protein homodimerization activity);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0005925(focal adhesion);GO:0005509(calcium ion binding);GO:0005829(cytosol);GO:0051015(actin filament binding);GO:0070062(extracellular exosome);GO:0007015(actin filament organization);GO:0042802(identical protein binding);GO:0046982(protein heterodimerization activity);GO:0001725(stress fiber);GO:0006936(muscle contraction);GO:0006928(movement of cell or subcellular component);GO:0008307(structural constituent of muscle);GO:0030049(muscle filament sliding);GO:0001649(osteoblast differentiation);GO:0005884(actin filament);GO:0005862(muscle thin filament tropomyosin);GO:0002102(podosome);GO:0015629(actin cytoskeleton);GO:0030863(cortical cytoskeleton);GO:0031941(filamentous actin);GO:0031941(filamentous actin)","04260(Cardiac muscle contraction);04261(Adrenergic signaling in cardiomyocytes);05410(Hypertrophic cardiomyopathy (HCM));05414(Dilated cardiomyopathy (DCM));05414(Dilated cardiomyopathy (DCM))","K10375","NA","tropomyosin 4 [Source:HGNC Symbol;Acc:HGNC:12013]",{"v":31.0900816003507,"d":"31.09"},{"v":24.9952793502832,"d":"25.00"},{"v":1.24383813297924,"d":"1.24"},{"v":0.314798752395874,"d":"0.31"},{"v":0.944989452138494,"d":"0.94"},{"v":0.996489349172959,"d":"1.00"},"up","no"]
["MSTRG.15092","TMEM250","MSTRG.15092.1;ENST00000561457;ENST00000447934;ENST00000557985;ENST00000418388","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005654(nucleoplasm);GO:0005515(protein binding);GO:0007049(cell cycle);GO:0016032(viral process);GO:0008284(positive regulation of cell proliferation);GO:0048524(positive regulation of viral process);GO:0048524(positive regulation of viral process)","NA","NA","NA","transmembrane protein 250 [Source:HGNC Symbol;Acc:HGNC:31009]",{"v":9.29411335020408,"d":"9.29"},{"v":7.47958896979592,"d":"7.48"},{"v":1.24259680414734,"d":"1.24"},{"v":0.313358248908782,"d":"0.31"},{"v":0.946787905927987,"d":"0.95"},{"v":0.996757582910332,"d":"1.00"},"up","no"]
["MSTRG.7322","ACTG1","ENST00000576214;ENST00000575842;ENST00000576209;ENST00000573283;MSTRG.7322.1;ENST00000575087;ENST00000572105;ENST00000576917;ENST00000571691;ENST00000331925;ENST00000576544;ENST00000615544;ENST00000571721;ENST00000570382;ENST00000575994;ENST00000574671;ENST00000575659","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0005886(plasma membrane);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0005615(extracellular space);GO:0038096(Fc-gamma receptor signaling pathway involved in phagocytosis);GO:0042802(identical protein binding);GO:0005200(structural constituent of cytoskeleton);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0061024(membrane organization);GO:0001895(retina homeostasis);GO:0072562(blood microparticle);GO:0031012(extracellular matrix);GO:0070527(platelet aggregation);GO:0048013(ephrin receptor signaling pathway);GO:0048010(vascular endothelial growth factor receptor signaling pathway);GO:0006928(movement of cell or subcellular component);GO:0031625(ubiquitin protein ligase binding);GO:0034329(cell junction assembly);GO:0097433(dense body);GO:0005925(focal adhesion);GO:0045214(sarcomere organization);GO:0015629(actin cytoskeleton);GO:0030016(myofibril);GO:0031941(filamentous actin);GO:0043209(myelin sheath);GO:0043209(myelin sheath)","04015(Rap1 signaling pathway);04390(Hippo signaling pathway);04145(Phagosome);04210(Apoptosis);04510(Focal adhesion);04520(Adherens junction);04530(Tight junction);04810(Regulation of actin cytoskeleton);04611(Platelet activation);04670(Leukocyte transendothelial migration);04921(Oxytocin signaling pathway);04919(Thyroid hormone signaling pathway);05205(Proteoglycans in cancer);05225(Hepatocellular carcinoma);05418(Fluid shear stress and atherosclerosis);05410(Hypertrophic cardiomyopathy (HCM));05412(Arrhythmogenic right ventricular cardiomyopathy (ARVC));05414(Dilated cardiomyopathy (DCM));05416(Viral myocarditis);05110(Vibrio cholerae infection);05130(Pathogenic Escherichia coli infection);05132(Salmonella infection);05131(Shigellosis);05100(Bacterial invasion of epithelial cells);05164(Influenza A);05164(Influenza A)","K05692","NA","actin gamma 1 [Source:HGNC Symbol;Acc:HGNC:144]",{"v":363.268813736666,"d":"363.27"},{"v":292.538322310634,"d":"292.54"},{"v":1.2417819684866,"d":"1.24"},{"v":0.312411888054319,"d":"0.31"},{"v":0.947440747584432,"d":"0.95"},{"v":0.996757582910332,"d":"1.00"},"up","no"]
["MSTRG.9369","WDR12","ENST00000478869;ENST00000463824;ENST00000464820;ENST00000475611;ENST00000261015","GO:0005634(nucleus);GO:0005515(protein binding);GO:0005654(nucleoplasm);GO:0042254(ribosome biogenesis);GO:0005730(nucleolus);GO:0006364(rRNA processing);GO:0008283(cell proliferation);GO:0043021(ribonucleoprotein complex binding);GO:0000463(maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA));GO:0000466(maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA));GO:0042273(ribosomal large subunit biogenesis);GO:0030687(preribosome, large subunit precursor);GO:0070545(PeBoW complex);GO:0007219(Notch signaling pathway);GO:0007219(Notch signaling pathway)","NA","NA","NA","WD repeat domain 12 [Source:HGNC Symbol;Acc:HGNC:14098]",{"v":0.787354654759288,"d":"0.79"},{"v":0.67428505770499,"d":"0.67"},{"v":1.16768812501814,"d":"1.17"},{"v":0.22365499975636,"d":"0.22"},{"v":0.949203378935146,"d":"0.95"},{"v":0.996773149518284,"d":"1.00"},"up","no"]
["MSTRG.12692","FAM8A1","ENST00000259963","GO:0016020(membrane);GO:0016021(integral component of membrane)","NA","NA","NA","family with sequence similarity 8 member A1 [Source:HGNC Symbol;Acc:HGNC:16372]",{"v":19.637453,"d":"19.64"},{"v":16.769247,"d":"16.77"},{"v":1.17103964179191,"d":"1.17"},{"v":0.227789914480098,"d":"0.23"},{"v":0.949687493407132,"d":"0.95"},{"v":0.996773149518284,"d":"1.00"},"up","no"]
["MSTRG.238","LYPLA2","ENST00000374514;ENST00000374503;ENST00000492577;ENST00000472213;ENST00000374501;ENST00000374502;ENST00000421070;ENST00000420982","GO:0005737(cytoplasm);GO:0016787(hydrolase activity);GO:0006629(lipid metabolic process);GO:0006631(fatty acid metabolic process);GO:0005829(cytosol);GO:0045296(cadherin binding);GO:0070062(extracellular exosome);GO:0007411(axon guidance);GO:0052689(carboxylic ester hydrolase activity);GO:0008474(palmitoyl-(protein) hydrolase activity);GO:0002084(protein depalmitoylation);GO:0002084(protein depalmitoylation)","00564(Glycerophospholipid metabolism);00564(Glycerophospholipid metabolism)","K06130","EC:3.1.1.5","lysophospholipase II [Source:HGNC Symbol;Acc:HGNC:6738]",{"v":13.1219898615665,"d":"13.12"},{"v":11.2014452008197,"d":"11.20"},{"v":1.17145507801139,"d":"1.17"},{"v":0.228301631987817,"d":"0.23"},{"v":0.951262908218062,"d":"0.95"},{"v":0.996773149518284,"d":"1.00"},"up","no"]
["ENSG00000135299","ANKRD6","ENST00000415924;ENST00000518253;ENST00000522441;ENST00000520839;ENST00000447838;ENST00000522705;ENST00000479572;ENST00000521240;ENST00000520886;ENST00000369408;ENST00000524056;ENST00000520793;ENST00000485637","GO:0043231(intracellular membrane-bounded organelle);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0090090(negative regulation of canonical Wnt signaling pathway);GO:0046330(positive regulation of JNK cascade);GO:2000096(positive regulation of Wnt signaling pathway, planar cell polarity pathway);GO:2000096(positive regulation of Wnt signaling pathway, planar cell polarity pathway)","NA","NA","NA","ankyrin repeat domain 6 [Source:HGNC Symbol;Acc:HGNC:17280]",{"v":0.424488101812943,"d":"0.42"},{"v":0.361966946091968,"d":"0.36"},{"v":1.17272614639539,"d":"1.17"},{"v":0.229866156278738,"d":"0.23"},{"v":0.952761254153784,"d":"0.95"},{"v":0.996773149518284,"d":"1.00"},"up","no"]
["MSTRG.7689","MPND","ENST00000599840;ENST00000596722;ENST00000359935;ENST00000594716;ENST00000262966;ENST00000594162;ENST00000597036;ENST00000601877","GO:0016787(hydrolase activity);GO:0008233(peptidase activity);GO:0006508(proteolysis);GO:0006508(proteolysis)","NA","NA","NA","MPN domain containing [Source:HGNC Symbol;Acc:HGNC:25934]",{"v":3.89385001464129,"d":"3.89"},{"v":3.14075220985847,"d":"3.14"},{"v":1.23978262354443,"d":"1.24"},{"v":0.310087188817011,"d":"0.31"},{"v":0.952995648224382,"d":"0.95"},{"v":0.996773149518284,"d":"1.00"},"up","no"]
["ENSG00000181754","AMIGO1","ENST00000369864;ENST00000369862","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0007155(cell adhesion);GO:0005887(integral component of plasma membrane);GO:0005886(plasma membrane);GO:0042995(cell projection);GO:0007275(multicellular organism development);GO:0065009(regulation of molecular function);GO:0007399(nervous system development);GO:0030154(cell differentiation);GO:0030425(dendrite);GO:0042552(myelination);GO:0030424(axon);GO:0043204(perikaryon);GO:0015459(potassium channel regulator activity);GO:0007156(homophilic cell adhesion via plasma membrane adhesion molecules);GO:0008076(voltage-gated potassium channel complex);GO:0050772(positive regulation of axonogenesis);GO:0007157(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules);GO:0032809(neuronal cell body membrane);GO:0007413(axonal fasciculation);GO:0007409(axonogenesis);GO:0051965(positive regulation of synapse assembly);GO:1901381(positive regulation of potassium ion transmembrane transport);GO:1901381(positive regulation of potassium ion transmembrane transport)","NA","NA","NA","adhesion molecule with Ig like domain 1 [Source:HGNC Symbol;Acc:HGNC:20824]",{"v":2.72552507484448,"d":"2.73"},{"v":2.2033354525661,"d":"2.20"},{"v":1.2369996006147,"d":"1.24"},{"v":0.306845034516965,"d":"0.31"},{"v":0.954701663384183,"d":"0.95"},{"v":0.997528456473375,"d":"1.00"},"up","no"]
["ENSG00000166165","CKB","ENST00000553528;ENST00000554705;ENST00000555039;ENST00000554426;ENST00000554989;ENST00000553994;ENST00000557569;ENST00000554282;ENST00000557287;ENST00000555770;ENST00000553878;ENST00000348956","GO:0005737(cytoplasm);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0005829(cytosol);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0003824(catalytic activity);GO:0016772(transferase activity, transferring phosphorus-containing groups);GO:0005515(protein binding);GO:0070062(extracellular exosome);GO:0005615(extracellular space);GO:0021762(substantia nigra development);GO:0031625(ubiquitin protein ligase binding);GO:0004111(creatine kinase activity);GO:0006600(creatine metabolic process);GO:0007420(brain development);GO:0021549(cerebellum development);GO:0030644(cellular chloride ion homeostasis);GO:0005634(nucleus);GO:0005739(mitochondrion);GO:0030425(dendrite);GO:0043025(neuronal cell body);GO:0043209(myelin sheath);GO:0043209(myelin sheath)","00330(Arginine and proline metabolism);00330(Arginine and proline metabolism)","K00933","EC:2.7.3.2","creatine kinase B [Source:HGNC Symbol;Acc:HGNC:1991]",{"v":0.377219056200824,"d":"0.38"},{"v":0.322611615961034,"d":"0.32"},{"v":1.16926681352474,"d":"1.17"},{"v":0.225604174204238,"d":"0.23"},{"v":0.956163411948085,"d":"0.96"},{"v":0.997657295862813,"d":"1.00"},"up","no"]
["ENSG00000134198","TSPAN2","ENST00000369516;ENST00000491992;ENST00000369515","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005515(protein binding);GO:0005887(integral component of plasma membrane);GO:0007166(cell surface receptor signaling pathway);GO:0006954(inflammatory response);GO:0007420(brain development);GO:0014002(astrocyte development);GO:0014005(microglia development);GO:0042552(myelination);GO:0048709(oligodendrocyte differentiation);GO:0061564(axon development);GO:0005886(plasma membrane);GO:0043209(myelin sheath);GO:0043209(myelin sheath)","NA","NA","NA","tetraspanin 2 [Source:HGNC Symbol;Acc:HGNC:20659]",{"v":3.08018073020528,"d":"3.08"},{"v":2.62608651319648,"d":"2.63"},{"v":1.17291670123087,"d":"1.17"},{"v":0.230100558985897,"d":"0.23"},{"v":0.958148243828447,"d":"0.96"},{"v":0.997877343837172,"d":"1.00"},"up","no"]
["ENSG00000116771","AGMAT","ENST00000375826","GO:0046872(metal ion binding);GO:0016787(hydrolase activity);GO:0016813(hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines);GO:0005739(mitochondrion);GO:0070062(extracellular exosome);GO:0008295(spermidine biosynthetic process);GO:0009446(putrescine biosynthetic process);GO:0097055(agmatine biosynthetic process);GO:0008783(agmatinase activity);GO:0033388(putrescine biosynthetic process from arginine)","00330(Arginine and proline metabolism)","K01480","EC:3.5.3.11","agmatinase [Source:HGNC Symbol;Acc:HGNC:18407]",{"v":1.439723,"d":"1.44"},{"v":1.225043,"d":"1.23"},{"v":1.17524282821093,"d":"1.18"},{"v":0.232958876671962,"d":"0.23"},{"v":0.959735156020528,"d":"0.96"},{"v":0.997877343837172,"d":"1.00"},"up","no"]
["ENSG00000135315","CEP162","ENST00000403245;ENST00000487999;ENST00000257766;ENST00000435955","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0005874(microtubule);GO:0005813(centrosome);GO:0005819(spindle);GO:0060271(cilium assembly);GO:0005829(cytosol);GO:0030030(cell projection organization);GO:0005814(centriole);GO:0097711(ciliary basal body docking);GO:0005879(axonemal microtubule);GO:0005879(axonemal microtubule)","NA","NA","NA","centrosomal protein 162 [Source:HGNC Symbol;Acc:HGNC:21107]",{"v":1.85315529082938,"d":"1.85"},{"v":1.49917374735111,"d":"1.50"},{"v":1.23611775760063,"d":"1.24"},{"v":0.305816186781176,"d":"0.31"},{"v":0.960502364445458,"d":"0.96"},{"v":0.997877343837172,"d":"1.00"},"up","no"]
["MSTRG.6961","SNX11","ENST00000393405;ENST00000582104;ENST00000359238;ENST00000584335;ENST00000452859;ENST00000581298;ENST00000581705;ENST00000582481;ENST00000577310;ENST00000578861;ENST00000580219;ENST00000580875;ENST00000583320","GO:0005622(intracellular);GO:0006886(intracellular protein transport);GO:0035091(phosphatidylinositol binding);GO:0006810(transport);GO:0016020(membrane);GO:0015031(protein transport);GO:0005515(protein binding);GO:0008289(lipid binding);GO:0005768(endosome);GO:0019898(extrinsic component of membrane);GO:0006897(endocytosis);GO:0016050(vesicle organization);GO:1901981(phosphatidylinositol phosphate binding);GO:1901981(phosphatidylinositol phosphate binding)","NA","NA","NA","sorting nexin 11 [Source:HGNC Symbol;Acc:HGNC:14975]",{"v":3.929802005269,"d":"3.93"},{"v":3.18960127454243,"d":"3.19"},{"v":1.23206685319398,"d":"1.23"},{"v":0.301080540249269,"d":"0.30"},{"v":0.961697003791111,"d":"0.96"},{"v":0.998050697500104,"d":"1.00"},"up","no"]
["ENSG00000070882","OSBPL3","ENST00000313367;ENST00000409069;ENST00000415162;ENST00000396429;ENST00000409759;ENST00000409863;ENST00000461835;ENST00000441059;ENST00000487020;ENST00000409452;ENST00000415952;ENST00000409555","GO:0006810(transport);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005829(cytosol);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005886(plasma membrane);GO:0042995(cell projection);GO:0005515(protein binding);GO:0006869(lipid transport);GO:0008289(lipid binding);GO:0031965(nuclear membrane);GO:0006699(bile acid biosynthetic process);GO:0015485(cholesterol binding);GO:0032433(filopodium tip);GO:0097038(perinuclear endoplasmic reticulum);GO:0015248(sterol transporter activity);GO:0015918(sterol transport);GO:0015918(sterol transport)","NA","NA","NA","oxysterol binding protein like 3 [Source:HGNC Symbol;Acc:HGNC:16370]",{"v":2.29522263,"d":"2.30"},{"v":1.94813569271605,"d":"1.95"},{"v":1.17816363540881,"d":"1.18"},{"v":0.23653992931924,"d":"0.24"},{"v":0.962583281703973,"d":"0.96"},{"v":0.998180533887279,"d":"1.00"},"up","no"]
["ENSG00000105699","LSR","ENST00000602122;ENST00000360798;ENST00000354900;ENST00000597933;ENST00000602003;ENST00000599658;ENST00000427250;ENST00000605618;ENST00000597446;ENST00000601623;ENST00000621372;ENST00000602044;ENST00000361790","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005886(plasma membrane);GO:0034361(very-low-density lipoprotein particle);GO:0042627(chylomicron);GO:0070062(extracellular exosome);GO:0034362(low-density lipoprotein particle);GO:0001889(liver development);GO:0019216(regulation of lipid metabolic process);GO:0060856(establishment of blood-brain barrier);GO:0061833(protein localization to tricellular tight junction);GO:1904274(tricellular tight junction assembly);GO:0061689(tricellular tight junction);GO:0061689(tricellular tight junction)","NA","NA","NA","lipolysis stimulated lipoprotein receptor [Source:HGNC Symbol;Acc:HGNC:29572]",{"v":2.3093905462963,"d":"2.31"},{"v":1.95485877880658,"d":"1.95"},{"v":1.18135927328017,"d":"1.18"},{"v":0.24044778180196,"d":"0.24"},{"v":0.964014150796125,"d":"0.96"},{"v":0.998180533887279,"d":"1.00"},"up","no"]
["ENSG00000100427","MLC1","ENST00000311597;ENST00000395876;ENST00000483836","GO:0006810(transport);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005783(endoplasmic reticulum);GO:0006811(ion transport);GO:0005886(plasma membrane);GO:0005901(caveola);GO:0048471(perinuclear region of cytoplasm);GO:0031410(cytoplasmic vesicle);GO:0045121(membrane raft);GO:0005764(lysosome);GO:0016192(vesicle-mediated transport);GO:0005515(protein binding);GO:0005768(endosome);GO:0016323(basolateral plasma membrane);GO:0005769(early endosome);GO:0055037(recycling endosome);GO:0051259(protein oligomerization);GO:0008565(protein transporter activity);GO:0032403(protein complex binding);GO:0005215(transporter activity);GO:0071397(cellular response to cholesterol);GO:0072584(caveolin-mediated endocytosis);GO:0032388(positive regulation of intracellular transport);GO:0047484(regulation of response to osmotic stress);GO:0015031(protein transport);GO:0005911(cell-cell junction);GO:0016324(apical plasma membrane);GO:0016324(apical plasma membrane)","NA","NA","NA","megalencephalic leukoencephalopathy with subcortical cysts 1 [Source:HGNC Symbol;Acc:HGNC:17082]",{"v":3.00776125901792,"d":"3.01"},{"v":2.44422666371887,"d":"2.44"},{"v":1.23055742074331,"d":"1.23"},{"v":0.299311978957241,"d":"0.30"},{"v":0.965100060685963,"d":"0.97"},{"v":0.998370479667387,"d":"1.00"},"up","no"]
["MSTRG.10551","RPL5P34","ENST00000426545","NA","NA","NA","NA","ribosomal protein L5 pseudogene 34 [Source:HGNC Symbol;Acc:HGNC:36463]",{"v":1.612323,"d":"1.61"},{"v":1.362312,"d":"1.36"},{"v":1.1835196342688,"d":"1.18"},{"v":0.243083640189358,"d":"0.24"},{"v":0.967193593828312,"d":"0.97"},{"v":0.998649719614751,"d":"1.00"},"up","no"]
["MSTRG.13635","MYO1G","ENST00000464434;ENST00000480503;ENST00000495831;ENST00000463516;ENST00000258787;ENST00000488554;ENST00000483585","GO:0016020(membrane);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0003774(motor activity);GO:0016459(myosin complex);GO:0003779(actin binding);GO:0005886(plasma membrane);GO:0042995(cell projection);GO:0002376(immune system process);GO:0002250(adaptive immune response);GO:0008289(lipid binding);GO:0005516(calmodulin binding);GO:0070062(extracellular exosome);GO:0001891(phagocytic cup);GO:0005546(phosphatidylinositol-4,5-bisphosphate binding);GO:0005547(phosphatidylinositol-3,4,5-trisphosphate binding);GO:0043325(phosphatidylinositol-3,4-bisphosphate binding);GO:0002456(T cell mediated immunity);GO:0006887(exocytosis);GO:0006909(phagocytosis);GO:0031589(cell-substrate adhesion);GO:0038096(Fc-gamma receptor signaling pathway involved in phagocytosis);GO:0071976(cell gliding);GO:0072678(T cell migration);GO:0005902(microvillus);GO:0030027(lamellipodium);GO:0030175(filopodium);GO:0031256(leading edge membrane);GO:0031256(leading edge membrane)","NA","NA","NA","myosin IG [Source:HGNC Symbol;Acc:HGNC:13880]",{"v":19.81896821611,"d":"19.82"},{"v":16.74153824974,"d":"16.74"},{"v":1.18382002420941,"d":"1.18"},{"v":0.24344976515873,"d":"0.24"},{"v":0.968520288014211,"d":"0.97"},{"v":0.998981400741658,"d":"1.00"},"up","no"]
["ENSG00000170191","NANP","ENST00000304788","GO:0016787(hydrolase activity);GO:0008152(metabolic process);GO:0016311(dephosphorylation);GO:0005975(carbohydrate metabolic process);GO:0005575(cellular_component);GO:0005829(cytosol);GO:0050124(N-acylneuraminate-9-phosphatase activity);GO:0006045(N-acetylglucosamine biosynthetic process);GO:0046380(N-acetylneuraminate biosynthetic process)","00520(Amino sugar and nucleotide sugar metabolism)","K01097","EC:3.1.3.29","N-acetylneuraminic acid phosphatase [Source:HGNC Symbol;Acc:HGNC:16140]",{"v":0.59952,"d":"0.60"},{"v":0.485227,"d":"0.49"},{"v":1.23554542513092,"d":"1.24"},{"v":0.305148052679158,"d":"0.31"},{"v":0.96908268561673,"d":"0.97"},{"v":0.998981400741658,"d":"1.00"},"up","no"]
["MSTRG.3955","FOXO1;LINC00598","ENST00000379561;ENST00000636651;ENST00000400431;ENST00000615137;ENST00000637124;ENST00000616706;ENST00000637523;ENST00000638163","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0005829(cytosol);GO:0005739(mitochondrion);GO:0043565(sequence-specific DNA binding);GO:0005515(protein binding);GO:0006974(cellular response to DNA damage stimulus);GO:0006915(apoptotic process);GO:0030154(cell differentiation);GO:0006914(autophagy);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0045893(positive regulation of transcription, DNA-templated);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0005654(nucleoplasm);GO:0045444(fat cell differentiation);GO:0010508(positive regulation of autophagy);GO:0003682(chromatin binding);GO:0009267(cellular response to starvation);GO:0000981(RNA polymerase II transcription factor activity, sequence-specific DNA binding);GO:0043065(positive regulation of apoptotic process);GO:0031625(ubiquitin protein ligase binding);GO:0009653(anatomical structure morphogenesis);GO:0034599(cellular response to oxidative stress);GO:0043066(negative regulation of apoptotic process);GO:0045892(negative regulation of transcription, DNA-templated);GO:0045599(negative regulation of fat cell differentiation);GO:0008286(insulin receptor signaling pathway);GO:0001678(cellular glucose homeostasis);GO:0032869(cellular response to insulin stimulus);GO:2000505(regulation of energy homeostasis);GO:0031018(endocrine pancreas development);GO:0008013(beta-catenin binding);GO:0051721(protein phosphatase 2A binding);GO:0045732(positive regulation of protein catabolic process);GO:0001659(temperature homeostasis);GO:0071455(cellular response to hyperoxia);GO:0032873(negative regulation of stress-activated MAPK cascade);GO:0071732(cellular response to nitric oxide);GO:0006473(protein acetylation);GO:0000989(transcription factor activity, transcription factor binding);GO:0001078(transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0001223(transcription coactivator binding);GO:0001227(transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding);GO:0008134(transcription factor binding);GO:0001568(blood vessel development);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0032868(response to insulin);GO:0035947(regulation of gluconeogenesis by regulation of transcription from RNA polymerase II promoter);GO:0042127(regulation of cell proliferation);GO:0042593(glucose homeostasis);GO:0045722(positive regulation of gluconeogenesis);GO:0070166(enamel mineralization);GO:0070301(cellular response to hydrogen peroxide);GO:0070417(cellular response to cold);GO:0071549(cellular response to dexamethasone stimulus);GO:0090090(negative regulation of canonical Wnt signaling pathway);GO:0097150(neuronal stem cell population maintenance);GO:1902617(response to fluoride);GO:2000177(regulation of neural precursor cell proliferation);GO:2000377(regulation of reactive oxygen species metabolic process);GO:2000377(regulation of reactive oxygen species metabolic process)","04068(FoxO signaling pathway);04152(AMPK signaling pathway);04218(Cellular senescence);04910(Insulin signaling pathway);04922(Glucagon signaling pathway);04919(Thyroid hormone signaling pathway);04211(Longevity regulating pathway - mammal);04213(Longevity regulating pathway - multiple species);05200(Pathways in cancer);05202(Transcriptional misregulation in cancers);05215(Prostate cancer);04931(Insulin resistance);04933(AGE-RAGE signaling pathway in diabetic complications);05165(Human papillomavirus infection);05165(Human papillomavirus infection)","K07201","NA","forkhead box O1 [Source:HGNC Symbol;Acc:HGNC:3819];long intergenic non-protein coding RNA 598 [Source:HGNC Symbol;Acc:HGNC:42770]",{"v":0.968045903146206,"d":"0.97"},{"v":0.790336196792104,"d":"0.79"},{"v":1.22485330556212,"d":"1.22"},{"v":0.292608975341489,"d":"0.29"},{"v":0.969834817020311,"d":"0.97"},{"v":0.998987217861212,"d":"1.00"},"up","no"]
["MSTRG.5169","APH1B","ENST00000261879;ENST00000380343;ENST00000559971;ENST00000560890;ENST00000380340;ENST00000558631;ENST00000560716","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016485(protein processing);GO:0043085(positive regulation of catalytic activity);GO:0007219(Notch signaling pathway);GO:0005886(plasma membrane);GO:0005783(endoplasmic reticulum);GO:0004175(endopeptidase activity);GO:0005887(integral component of plasma membrane);GO:0005515(protein binding);GO:0008233(peptidase activity);GO:0007220(Notch receptor processing);GO:0070765(gamma-secretase complex);GO:0048013(ephrin receptor signaling pathway);GO:0043065(positive regulation of apoptotic process);GO:0031293(membrane protein intracellular domain proteolysis);GO:0030133(transport vesicle);GO:0030133(transport vesicle)","04330(Notch signaling pathway);05010(Alzheimer's disease);05010(Alzheimer's disease)","K06172","NA","aph-1 homolog B, gamma-secretase subunit [Source:HGNC Symbol;Acc:HGNC:24080]",{"v":2.24715432289771,"d":"2.25"},{"v":1.83318340407718,"d":"1.83"},{"v":1.22582078688898,"d":"1.23"},{"v":0.293748074652345,"d":"0.29"},{"v":0.971700283117403,"d":"0.97"},{"v":0.998987217861212,"d":"1.00"},"up","no"]
["ENSG00000186187","ZNRF1","ENST00000335325;ENST00000579084;ENST00000566250;ENST00000566244;ENST00000568844;ENST00000564320;ENST00000568511;ENST00000320619;ENST00000568494","GO:0016020(membrane);GO:0046872(metal ion binding);GO:0016740(transferase activity);GO:0016567(protein ubiquitination);GO:0005515(protein binding);GO:0030054(cell junction);GO:0045202(synapse);GO:0031410(cytoplasmic vesicle);GO:0005764(lysosome);GO:0043161(proteasome-mediated ubiquitin-dependent protein catabolic process);GO:0005768(endosome);GO:0005829(cytosol);GO:0000209(protein polyubiquitination);GO:0004842(ubiquitin-protein transferase activity);GO:0030672(synaptic vesicle membrane);GO:0070936(protein K48-linked ubiquitination);GO:0061630(ubiquitin protein ligase activity);GO:0061630(ubiquitin protein ligase activity)","NA","NA","NA","zinc and ring finger 1 [Source:HGNC Symbol;Acc:HGNC:18452]",{"v":0.197804745920218,"d":"0.20"},{"v":0.168802659791478,"d":"0.17"},{"v":1.17181059922022,"d":"1.17"},{"v":0.228739404532201,"d":"0.23"},{"v":0.97378665042695,"d":"0.97"},{"v":0.998987217861212,"d":"1.00"},"up","no"]
["MSTRG.2970","SENCR","ENST00000526269","NA","NA","NA","NA","smooth muscle and endothelial cell enriched migration/differentiation-associated long non-coding RNA [Source:HGNC Symbol;Acc:HGNC:44177]",{"v":1.469169,"d":"1.47"},{"v":1.189144,"d":"1.19"},{"v":1.23548451659345,"d":"1.24"},{"v":0.305076930558386,"d":"0.31"},{"v":0.974544436320359,"d":"0.97"},{"v":0.998987217861212,"d":"1.00"},"up","no"]
["ENSG00000134987","WDR36","ENST00000612402;ENST00000506538;ENST00000513710;ENST00000515784;ENST00000505303","GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005730(nucleolus);GO:0042254(ribosome biogenesis);GO:0050896(response to stimulus);GO:0006364(rRNA processing);GO:0032040(small-subunit processome);GO:0034388(Pwp2p-containing subcomplex of 90S preribosome);GO:0008150(biological_process);GO:0005575(cellular_component);GO:0005654(nucleoplasm);GO:0007601(visual perception);GO:0001895(retina homeostasis);GO:0030516(regulation of axon extension);GO:0030516(regulation of axon extension)","03008(Ribosome biogenesis in eukaryotes);03008(Ribosome biogenesis in eukaryotes)","K14554","NA","WD repeat domain 36 [Source:HGNC Symbol;Acc:HGNC:30696]",{"v":2.34205044592477,"d":"2.34"},{"v":1.91491661859979,"d":"1.91"},{"v":1.22305609715649,"d":"1.22"},{"v":0.290490576582753,"d":"0.29"},{"v":0.974924043881902,"d":"0.97"},{"v":0.999099269467043,"d":"1.00"},"up","no"]
["MSTRG.1928","NOLC1","ENST00000605788;ENST00000405356;ENST00000370007;ENST00000488254;ENST00000476468;ENST00000603946;ENST00000461421","GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0005730(nucleolus);GO:0005525(GTP binding);GO:0005515(protein binding);GO:0006417(regulation of translation);GO:0046982(protein heterodimerization activity);GO:0006364(rRNA processing);GO:0000278(mitotic cell cycle);GO:0007049(cell cycle);GO:0014029(neural crest formation);GO:0014032(neural crest cell development);GO:0001042(RNA polymerase I core binding);GO:0007000(nucleolus organization);GO:0005654(nucleoplasm);GO:0015030(Cajal body);GO:0015030(Cajal body)","NA","NA","NA","nucleolar and coiled-body phosphoprotein 1 [Source:HGNC Symbol;Acc:HGNC:15608]",{"v":10.3937100481108,"d":"10.39"},{"v":8.50891814030227,"d":"8.51"},{"v":1.22150781999903,"d":"1.22"},{"v":0.288663099657321,"d":"0.29"},{"v":0.977421092682226,"d":"0.98"},{"v":0.999476443782316,"d":"1.00"},"up","no"]
["ENSG00000164631","ZNF12","ENST00000404360;ENST00000405858;ENST00000491565;ENST00000394917;ENST00000342651","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0005654(nucleoplasm);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0005622(intracellular);GO:0005813(centrosome);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0045892(negative regulation of transcription, DNA-templated);GO:0045892(negative regulation of transcription, DNA-templated)","NA","NA","NA","zinc finger protein 12 [Source:HGNC Symbol;Acc:HGNC:12902]",{"v":4.89552745327544,"d":"4.90"},{"v":4.11513099811214,"d":"4.12"},{"v":1.18964073209852,"d":"1.19"},{"v":0.250525949771394,"d":"0.25"},{"v":0.97773600966448,"d":"0.98"},{"v":0.999476443782316,"d":"1.00"},"up","no"]
["MSTRG.2267","ARNTL","ENST00000403290;ENST00000403482;ENST00000403510;ENST00000472842;ENST00000389707;MSTRG.2267.12;ENST00000531665;ENST00000529825;ENST00000497429;ENST00000529390;ENST00000533520;ENST00000529388;ENST00000534102;ENST00000485918;ENST00000524392;ENST00000480685;ENST00000482049","GO:0046983(protein dimerization activity);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0043231(intracellular membrane-bounded organelle);GO:0005654(nucleoplasm);GO:0006355(regulation of transcription, DNA-templated);GO:0006366(transcription from RNA polymerase II promoter);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0005515(protein binding);GO:0048511(rhythmic process);GO:0005667(transcription factor complex);GO:0045893(positive regulation of transcription, DNA-templated);GO:0007283(spermatogenesis);GO:0001047(core promoter binding);GO:0043565(sequence-specific DNA binding);GO:0090263(positive regulation of canonical Wnt signaling pathway);GO:0045892(negative regulation of transcription, DNA-templated);GO:0043161(proteasome-mediated ubiquitin-dependent protein catabolic process);GO:0000976(transcription regulatory region sequence-specific DNA binding);GO:0000982(transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0017162(aryl hydrocarbon receptor binding);GO:0051879(Hsp90 protein binding);GO:0070491(repressing transcription factor binding);GO:0070888(E-box binding);GO:0007623(circadian rhythm);GO:0032007(negative regulation of TOR signaling);GO:0032922(circadian regulation of gene expression);GO:0042634(regulation of hair cycle);GO:0042753(positive regulation of circadian rhythm);GO:0045599(negative regulation of fat cell differentiation);GO:0050767(regulation of neurogenesis);GO:0050796(regulation of insulin secretion);GO:0051726(regulation of cell cycle);GO:0051775(response to redox state);GO:0090403(oxidative stress-induced premature senescence);GO:2000074(regulation of type B pancreatic cell development);GO:2000323(negative regulation of glucocorticoid receptor signaling pathway);GO:2000772(regulation of cellular senescence);GO:2001016(positive regulation of skeletal muscle cell differentiation);GO:0016605(PML body);GO:0033391(chromatoid body);GO:0001046(core promoter sequence-specific DNA binding);GO:0001190(transcriptional activator activity, RNA polymerase II transcription factor binding);GO:0043425(bHLH transcription factor binding);GO:0046982(protein heterodimerization activity);GO:0000060(protein import into nucleus, translocation);GO:0042176(regulation of protein catabolic process);GO:0060137(maternal process involved in parturition);GO:0016604(nuclear body);GO:0016604(nuclear body)","04728(Dopaminergic synapse);04710(Circadian rhythm);05168(Herpes simplex infection);05168(Herpes simplex infection)","K02296","NA","aryl hydrocarbon receptor nuclear translocator like [Source:HGNC Symbol;Acc:HGNC:701]",{"v":6.44636911983348,"d":"6.45"},{"v":5.4156832995837,"d":"5.42"},{"v":1.19031500980292,"d":"1.19"},{"v":0.251343424743067,"d":"0.25"},{"v":0.978925913859318,"d":"0.98"},{"v":0.999476443782316,"d":"1.00"},"up","no"]
["MSTRG.13387","EZR","ENST00000337147;ENST00000367075;ENST00000476189;ENST00000392177","GO:0045177(apical part of cell);GO:0003723(RNA binding);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0003779(actin binding);GO:0001650(fibrillar center);GO:0005886(plasma membrane);GO:0005829(cytosol);GO:0005856(cytoskeleton);GO:0042995(cell projection);GO:0005515(protein binding);GO:0008092(cytoskeletal protein binding);GO:0048471(perinuclear region of cytoplasm);GO:0005615(extracellular space);GO:0048015(phosphatidylinositol-mediated signaling);GO:0005925(focal adhesion);GO:0008017(microtubule binding);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0005768(endosome);GO:0045296(cadherin binding);GO:0051015(actin filament binding);GO:0030175(filopodium);GO:0070062(extracellular exosome);GO:0010628(positive regulation of gene expression);GO:0071944(cell periphery);GO:0005938(cell cortex);GO:0032587(ruffle membrane);GO:0016323(basolateral plasma membrane);GO:0071437(invadopodium);GO:0019898(extrinsic component of membrane);GO:0005903(brush border);GO:0008360(regulation of cell shape);GO:0001726(ruffle);GO:0016324(apical plasma membrane);GO:0019904(protein domain specific binding);GO:0051017(actin filament bundle assembly);GO:0031982(vesicle);GO:0007411(axon guidance);GO:0061028(establishment of endothelial barrier);GO:0050714(positive regulation of protein secretion);GO:0031528(microvillus membrane);GO:0098592(cytoplasmic side of apical plasma membrane);GO:0044548(S100 protein binding);GO:0070373(negative regulation of ERK1 and ERK2 cascade);GO:0030033(microvillus assembly);GO:0090002(establishment of protein localization to plasma membrane);GO:0015629(actin cytoskeleton);GO:0001772(immunological synapse);GO:0031532(actin cytoskeleton reorganization);GO:0034236(protein kinase A catalytic subunit binding);GO:0034237(protein kinase A regulatory subunit binding);GO:0071320(cellular response to cAMP);GO:0051117(ATPase binding);GO:0003376(sphingosine-1-phosphate signaling pathway);GO:0046847(filopodium assembly);GO:0005902(microvillus);GO:0044853(plasma membrane raft);GO:0050839(cell adhesion molecule binding);GO:0050860(negative regulation of T cell receptor signaling pathway);GO:0007159(leukocyte cell-cell adhesion);GO:0022614(membrane to membrane docking);GO:0010737(protein kinase A signaling);GO:1900041(negative regulation of interleukin-2 secretion);GO:0007016(cytoskeletal anchoring at plasma membrane);GO:0030953(astral microtubule organization);GO:0034629(cellular protein complex localization);GO:0043622(cortical microtubule organization);GO:0051660(establishment of centrosome localization);GO:0072697(protein localization to cell cortex);GO:1902115(regulation of organelle assembly);GO:1902966(positive regulation of protein localization to early endosome);GO:1903364(positive regulation of cellular protein catabolic process);GO:1903753(negative regulation of p38MAPK cascade);GO:2000643(positive regulation of early endosome to late endosome transport);GO:0005884(actin filament);GO:0030863(cortical cytoskeleton);GO:0008022(protein C-terminus binding);GO:0032403(protein complex binding);GO:0097718(disordered domain specific binding);GO:0001951(intestinal D-glucose absorption);GO:0030855(epithelial cell differentiation);GO:0031623(receptor internalization);GO:0032532(regulation of microvillus length);GO:0035088(establishment or maintenance of apical/basal cell polarity);GO:0040018(positive regulation of multicellular organism growth);GO:0090004(positive regulation of establishment of protein localization to plasma membrane);GO:1902896(terminal web assembly);GO:0001931(uropod);GO:0005622(intracellular);GO:0030315(T-tubule);GO:0036064(ciliary basal body);GO:0043209(myelin sheath);GO:0044297(cell body);GO:0044393(microspike);GO:0045121(membrane raft);GO:0051286(cell tip);GO:0097449(astrocyte projection);GO:0097454(Schwann cell microvillus);GO:0097454(Schwann cell microvillus)","04530(Tight junction);04810(Regulation of actin cytoskeleton);04670(Leukocyte transendothelial migration);04971(Gastric acid secretion);05206(MicroRNAs in cancer);05205(Proteoglycans in cancer);05130(Pathogenic Escherichia coli infection);05130(Pathogenic Escherichia coli infection)","K08007","NA","ezrin [Source:HGNC Symbol;Acc:HGNC:12691]",{"v":31.4970376618791,"d":"31.50"},{"v":25.8467933979653,"d":"25.85"},{"v":1.21860523187215,"d":"1.22"},{"v":0.285230839444394,"d":"0.29"},{"v":0.981096512157931,"d":"0.98"},{"v":0.9996591387492,"d":"1.00"},"up","no"]
["ENSG00000175556","LONRF3","ENST00000304778;ENST00000371628;ENST00000439603;ENST00000422289;ENST00000481285","GO:0046872(metal ion binding);GO:0005515(protein binding);GO:0005622(intracellular);GO:0061630(ubiquitin protein ligase activity);GO:0000209(protein polyubiquitination);GO:0032436(positive regulation of proteasomal ubiquitin-dependent protein catabolic process);GO:0031624(ubiquitin conjugating enzyme binding);GO:0031624(ubiquitin conjugating enzyme binding)","NA","NA","NA","LON peptidase N-terminal domain and ring finger 3 [Source:HGNC Symbol;Acc:HGNC:21152]",{"v":0.677737476862163,"d":"0.68"},{"v":0.554755219500124,"d":"0.55"},{"v":1.22168742724558,"d":"1.22"},{"v":0.288875214087936,"d":"0.29"},{"v":0.982243092047592,"d":"0.98"},{"v":0.9996591387492,"d":"1.00"},"up","no"]
["ENSG00000152952","PLOD2","ENST00000282903;ENST00000480704;ENST00000460520;ENST00000461497;ENST00000494950;ENST00000360060","GO:0016020(membrane);GO:0046872(metal ion binding);GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0005783(endoplasmic reticulum);GO:0005506(iron ion binding);GO:0016705(oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen);GO:0031418(L-ascorbic acid binding);GO:0008475(procollagen-lysine 5-dioxygenase activity);GO:0051213(dioxygenase activity);GO:0005789(endoplasmic reticulum membrane);GO:0070062(extracellular exosome);GO:0001666(response to hypoxia);GO:0006464(cellular protein modification process);GO:0017185(peptidyl-lysine hydroxylation);GO:0046947(hydroxylysine biosynthetic process);GO:0030867(rough endoplasmic reticulum membrane);GO:0030867(rough endoplasmic reticulum membrane)","00310(Lysine degradation);00310(Lysine degradation)","K13645","EC:1.14.11.4","procollagen-lysine,2-oxoglutarate 5-dioxygenase 2 [Source:HGNC Symbol;Acc:HGNC:9082]",{"v":0.180425132356788,"d":"0.18"},{"v":0.145220600575464,"d":"0.15"},{"v":1.24242105900829,"d":"1.24"},{"v":0.313154188692763,"d":"0.31"},{"v":0.982707070217848,"d":"0.98"},{"v":0.9996591387492,"d":"1.00"},"up","no"]
["MSTRG.4705","TDRD9","ENST00000409874;ENST00000466378;ENST00000462273;ENST00000481318;ENST00000339063;ENST00000557332","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0016787(hydrolase activity);GO:0004386(helicase activity);GO:0007275(multicellular organism development);GO:0051321(meiotic cell cycle);GO:0030154(cell differentiation);GO:0031047(gene silencing by RNA);GO:0007283(spermatogenesis);GO:0005739(mitochondrion);GO:0003723(RNA binding);GO:0004004(ATP-dependent RNA helicase activity);GO:0034587(piRNA metabolic process);GO:0043046(DNA methylation involved in gamete generation);GO:0009566(fertilization);GO:0043186(P granule);GO:0006396(RNA processing);GO:0007140(male meiotic nuclear division);GO:0071547(piP-body);GO:0071547(piP-body)","NA","NA","NA","tudor domain containing 9 [Source:HGNC Symbol;Acc:HGNC:20122]",{"v":0.826223519343066,"d":"0.83"},{"v":0.676860616788321,"d":"0.68"},{"v":1.22067010378513,"d":"1.22"},{"v":0.287673352708014,"d":"0.29"},{"v":0.983684642197465,"d":"0.98"},{"v":0.9996591387492,"d":"1.00"},"up","no"]
["MSTRG.14259","CCDC25","ENST00000356537;ENST00000520202;ENST00000521220;ENST00000519843;ENST00000519509;ENST00000523841;ENST00000517979;ENST00000520486","GO:0005515(protein binding);GO:0070062(extracellular exosome);GO:0070062(extracellular exosome)","NA","NA","NA","coiled-coil domain containing 25 [Source:HGNC Symbol;Acc:HGNC:25591]",{"v":2.68637521540204,"d":"2.69"},{"v":2.20995486296716,"d":"2.21"},{"v":1.21557922309563,"d":"1.22"},{"v":0.281643921373751,"d":"0.28"},{"v":0.985317427362838,"d":"0.99"},{"v":0.99995554347327,"d":"1.00"},"up","no"]
["MSTRG.13792","ZNF655;TMEM225B","ENST00000424881;ENST00000425063;ENST00000467680;ENST00000494357;ENST00000320583;ENST00000452314;ENST00000419215;ENST00000488751;ENST00000412636;ENST00000252713;ENST00000449244;ENST00000394163;ENST00000626122;ENST00000453227;ENST00000422164;ENST00000440391;ENST00000431679;ENST00000422647;ENST00000416144;ENST00000493947;ENST00000357864;ENST00000454654;ENST00000489320;ENST00000423973;ENST00000493277","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0005730(nucleolus);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0003674(molecular_function);GO:2000134(negative regulation of G1/S transition of mitotic cell cycle);GO:0005622(intracellular);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0010923(negative regulation of phosphatase activity);GO:0005622(intracellular)","NA","NA","NA","zinc finger protein 655 [Source:HGNC Symbol;Acc:HGNC:30899];transmembrane protein 225B [Source:HGNC Symbol;Acc:HGNC:53075]",{"v":4.04472574773214,"d":"4.04"},{"v":3.38113210447457,"d":"3.38"},{"v":1.19626374325315,"d":"1.20"},{"v":0.258535499180908,"d":"0.26"},{"v":0.986234214410511,"d":"0.99"},1,"up","no"]
["MSTRG.1037","GBAP1","ENST00000368374;ENST00000486197;ENST00000463838;ENST00000473223;ENST00000462587;ENST00000459805","NA","NA","NA","NA","glucosylceramidase beta pseudogene 1 [Source:HGNC Symbol;Acc:HGNC:4178]",{"v":1.06960330935449,"d":"1.07"},{"v":0.896560032002188,"d":"0.90"},{"v":1.19300802085262,"d":"1.19"},{"v":0.254603742618552,"d":"0.25"},{"v":0.987568480730408,"d":"0.99"},1,"up","no"]
["MSTRG.5089","MAPK6","ENST00000261845;ENST00000560774;ENST00000558100;ENST00000558841","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0005829(cytosol);GO:0016740(transferase activity);GO:0004707(MAP kinase activity);GO:0016301(kinase activity);GO:0000165(MAPK cascade);GO:0016310(phosphorylation);GO:0005515(protein binding);GO:0007049(cell cycle);GO:0005654(nucleoplasm);GO:0010468(regulation of gene expression);GO:0007165(signal transduction);GO:0071310(cellular response to organic substance);GO:0019901(protein kinase binding);GO:0046982(protein heterodimerization activity);GO:0060999(positive regulation of dendritic spine development);GO:0032156(septin cytoskeleton);GO:0043234(protein complex);GO:0043234(protein complex)","04657(IL-17 signaling pathway);04657(IL-17 signaling pathway)","K06855","EC:2.7.11.24","mitogen-activated protein kinase 6 [Source:HGNC Symbol;Acc:HGNC:6879]",{"v":2.28166167298059,"d":"2.28"},{"v":1.88041259971822,"d":"1.88"},{"v":1.21338352727614,"d":"1.21"},{"v":0.279035630791743,"d":"0.28"},{"v":0.989450505380224,"d":"0.99"},1,"up","no"]
["ENSG00000159885","ZNF222","ENST00000391960;ENST00000587846;ENST00000590160;ENST00000187879","GO:0003676(nucleic acid binding);GO:0006355(regulation of transcription, DNA-templated);GO:0005622(intracellular);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0003677(DNA binding)","NA","NA","NA","zinc finger protein 222 [Source:HGNC Symbol;Acc:HGNC:13015]",{"v":1.22475513729406,"d":"1.22"},{"v":1.00446161707439,"d":"1.00"},{"v":1.21931502057918,"d":"1.22"},{"v":0.286070906854817,"d":"0.29"},{"v":0.990097772630798,"d":"0.99"},1,"up","no"]
["ENSG00000050393","MCUR1","ENST00000379170;ENST00000607303;ENST00000488770","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005743(mitochondrial inner membrane);GO:0005739(mitochondrion);GO:0006811(ion transport);GO:0031305(integral component of mitochondrial inner membrane);GO:0006816(calcium ion transport);GO:0005515(protein binding);GO:0006851(mitochondrial calcium ion transmembrane transport);GO:0051561(positive regulation of mitochondrial calcium ion concentration);GO:0070509(calcium ion import);GO:0036444(mitochondrial calcium uptake);GO:0036444(mitochondrial calcium uptake)","NA","NA","NA","mitochondrial calcium uniporter regulator 1 [Source:HGNC Symbol;Acc:HGNC:21097]",{"v":3.22931442909031,"d":"3.23"},{"v":2.66504392025755,"d":"2.67"},{"v":1.21173028502218,"d":"1.21"},{"v":0.277068609896833,"d":"0.28"},{"v":0.992636154121188,"d":"0.99"},1,"up","no"]
["MSTRG.11009","ARHGEF3","ENST00000496106;ENST00000296315;ENST00000481422;ENST00000486829;ENST00000465659;ENST00000495373;ENST00000498517;ENST00000497267;ENST00000338458;ENST00000413728","GO:0005737(cytoplasm);GO:0035556(intracellular signal transduction);GO:0005089(Rho guanyl-nucleotide exchange factor activity);GO:0035023(regulation of Rho protein signal transduction);GO:0043547(positive regulation of GTPase activity);GO:0005515(protein binding);GO:0005085(guanyl-nucleotide exchange factor activity);GO:0005829(cytosol);GO:0051056(regulation of small GTPase mediated signal transduction);GO:0007266(Rho protein signal transduction);GO:0043065(positive regulation of apoptotic process);GO:0005622(intracellular);GO:0005622(intracellular)","NA","NA","NA","Rho guanine nucleotide exchange factor 3 [Source:HGNC Symbol;Acc:HGNC:683]",{"v":12.6218330007583,"d":"12.62"},{"v":10.5090599532909,"d":"10.51"},{"v":1.20104301020814,"d":"1.20"},{"v":0.264287815908607,"d":"0.26"},{"v":0.993338559040176,"d":"0.99"},1,"up","no"]
["ENSG00000147854","UHRF2","ENST00000484159;ENST00000468435;ENST00000276893;ENST00000485617;ENST00000481049;ENST00000492853;ENST00000381373;ENST00000477183;ENST00000461236;ENST00000481243;ENST00000450508;ENST00000479000","GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0005654(nucleoplasm);GO:0016740(transferase activity);GO:0016567(protein ubiquitination);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0007049(cell cycle);GO:0042393(histone binding);GO:0071158(positive regulation of cell cycle arrest);GO:0061630(ubiquitin protein ligase activity);GO:0051726(regulation of cell cycle);GO:0005720(nuclear heterochromatin);GO:0004842(ubiquitin-protein transferase activity);GO:0008283(cell proliferation);GO:0010216(maintenance of DNA methylation);GO:0030154(cell differentiation);GO:0051865(protein autoubiquitination);GO:0090308(regulation of methylation-dependent chromatin silencing);GO:0090308(regulation of methylation-dependent chromatin silencing)","NA","NA","NA","ubiquitin like with PHD and ring finger domains 2 [Source:HGNC Symbol;Acc:HGNC:12557]",{"v":2.48572611563666,"d":"2.49"},{"v":2.06889690281278,"d":"2.07"},{"v":1.20147413448064,"d":"1.20"},{"v":0.264805590242076,"d":"0.26"},{"v":0.995516541013023,"d":"1.00"},1,"up","no"]
["ENSG00000143643","TTC13","ENST00000366662;ENST00000366661;ENST00000486879;ENST00000471302;ENST00000519379;ENST00000466507;ENST00000481976;ENST00000522821","NA","NA","NA","NA","tetratricopeptide repeat domain 13 [Source:HGNC Symbol;Acc:HGNC:26204]",{"v":4.65899208760684,"d":"4.66"},{"v":3.8726505365622,"d":"3.87"},{"v":1.20304996374465,"d":"1.20"},{"v":0.26669656017798,"d":"0.27"},{"v":0.996149745270636,"d":"1.00"},1,"up","no"]
["MSTRG.2885","PCSK7","ENST00000534529;ENST00000320934;ENST00000532810;ENST00000528973;ENST00000528217;ENST00000532301;ENST00000524507;ENST00000529458;ENST00000533135;ENST00000527861;ENST00000527037;ENST00000525027;ENST00000531573","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016787(hydrolase activity);GO:0005794(Golgi apparatus);GO:0008233(peptidase activity);GO:0006508(proteolysis);GO:0004252(serine-type endopeptidase activity);GO:0008236(serine-type peptidase activity);GO:0030173(integral component of Golgi membrane);GO:0016486(peptide hormone processing);GO:0016485(protein processing);GO:0016485(protein processing)","NA","NA","NA","proprotein convertase subtilisin/kexin type 7 [Source:HGNC Symbol;Acc:HGNC:8748]",{"v":2.43435752934583,"d":"2.43"},{"v":2.02319811195803,"d":"2.02"},{"v":1.20322251931616,"d":"1.20"},{"v":0.266903473625624,"d":"0.27"},{"v":0.998297799903078,"d":"1.00"},1,"up","no"]
["ENSG00000250532","AC021180.1","ENST00000508581","NA","NA","NA","NA",null,0,{"v":0.007852,"d":"0.01"},"-inf","-inf",1,1,"down","no"]
["ENSG00000228175","GEMIN8P4","ENST00000380526","NA","NA","NA","NA","gem nuclear organelle associated protein 8 pseudogene 4 [Source:HGNC Symbol;Acc:HGNC:37979]",{"v":0.072867,"d":"0.07"},0,"inf","inf",1,1,"up","no"]
["ENSG00000155760","FZD7","ENST00000286201","GO:0010812(negative regulation of cell-substrate adhesion);GO:2000726(negative regulation of cardiac muscle cell differentiation);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0004871(signal transducer activity);GO:0007165(signal transduction);GO:0004888(transmembrane signaling receptor activity);GO:0004930(G-protein coupled receptor activity);GO:0007166(cell surface receptor signaling pathway);GO:0007186(G-protein coupled receptor signaling pathway);GO:0007275(multicellular organism development);GO:0016055(Wnt signaling pathway);GO:0042813(Wnt-activated receptor activity);GO:0005768(endosome);GO:0060071(Wnt signaling pathway, planar cell polarity pathway);GO:0017147(Wnt-protein binding);GO:0010008(endosome membrane);GO:0055038(recycling endosome membrane);GO:0005546(phosphatidylinositol-4,5-bisphosphate binding);GO:0045893(positive regulation of transcription, DNA-templated);GO:0042327(positive regulation of phosphorylation);GO:0046330(positive regulation of JNK cascade);GO:0030182(neuron differentiation);GO:0060070(canonical Wnt signaling pathway);GO:0071300(cellular response to retinoic acid);GO:0060054(positive regulation of epithelial cell proliferation involved in wound healing);GO:0030165(PDZ domain binding);GO:0005109(frizzled binding);GO:0006355(regulation of transcription, DNA-templated);GO:0014834(skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration);GO:0019827(stem cell population maintenance);GO:0033077(T cell differentiation in thymus);GO:0034446(substrate adhesion-dependent cell spreading);GO:0035412(regulation of catenin import into nucleus);GO:0035567(non-canonical Wnt signaling pathway);GO:0038031(non-canonical Wnt signaling pathway via JNK cascade);GO:0042666(negative regulation of ectodermal cell fate specification);GO:0048103(somatic stem cell division);GO:0060231(mesenchymal to epithelial transition)","04310(Wnt signaling pathway);04390(Hippo signaling pathway);04150(mTOR signaling pathway);04550(Signaling pathways regulating pluripotency of stem cells);04916(Melanogenesis);05200(Pathways in cancer);05205(Proteoglycans in cancer);05225(Hepatocellular carcinoma);05226(Gastric cancer);05217(Basal cell carcinoma);05224(Breast cancer);05166(HTLV-I infection);05165(Human papillomavirus infection)","K02432","NA","frizzled class receptor 7 [Source:HGNC Symbol;Acc:HGNC:4045]",{"v":0.122246,"d":"0.12"},{"v":0.03952,"d":"0.04"},{"v":3.09326923076923,"d":"3.09"},{"v":1.62913240762428,"d":"1.63"},1,1,"up","no"]
["ENSG00000215206","TRBV24OR9-2","ENST00000416632","NA","NA","NA","NA","T-cell receptor beta variable 24/OR9-2 (pseudogene) [Source:HGNC Symbol;Acc:HGNC:12204]",0,0,1,0,1,1,"no","no"]
["ENSG00000244245","AC133134.1","ENST00000466800","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["MSTRG.3467","RN7SL809P","ENST00000482040","NA","NA","NA","NA","RNA, 7SL, cytoplasmic 809, pseudogene [Source:HGNC Symbol;Acc:HGNC:46825]",{"v":0.212399,"d":"0.21"},0,"inf","inf",1,1,"up","no"]
["ENSG00000241484","ARHGAP8","ENST00000412433;ENST00000460809;ENST00000469872;ENST00000498310;ENST00000469342;ENST00000389774","GO:0070374(positive regulation of ERK1 and ERK2 cascade);GO:0007165(signal transduction);GO:0043547(positive regulation of GTPase activity);GO:0005515(protein binding);GO:0005096(GTPase activator activity);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0051056(regulation of small GTPase mediated signal transduction);GO:0051056(regulation of small GTPase mediated signal transduction)","NA","NA","NA","Rho GTPase activating protein 8 [Source:HGNC Symbol;Acc:HGNC:677]",{"v":0.0641139825651303,"d":"0.06"},{"v":0.00733569358717435,"d":"0.01"},{"v":8.74000280999012,"d":"8.74"},{"v":3.12763374356548,"d":"3.13"},1,1,"up","no"]
["ENSG00000155622","XAGE2","ENST00000286049","GO:0005515(protein binding)","NA","NA","NA","X antigen family member 2 [Source:HGNC Symbol;Acc:HGNC:4112]",0,0,1,0,1,1,"no","no"]
["ENSG00000280129","AL132780.5","ENST00000623843","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000251517","AC096734.1","ENST00000511279","NA","NA","NA","NA",null,{"v":0.09356,"d":"0.09"},0,"inf","inf",1,1,"up","no"]
["ENSG00000188755","TBC1D3P2","ENST00000581291","NA","NA","NA","NA","TBC1 domain family member 3 pseudogene 2 [Source:HGNC Symbol;Acc:HGNC:27783]",0,0,1,0,1,1,"no","no"]
["ENSG00000258457","AL132780.2","ENST00000555294;ENST00000557615","NA","NA","NA","NA",null,{"v":0.0689789555403557,"d":"0.07"},{"v":0.138777928180575,"d":"0.14"},{"v":0.497045578102317,"d":"0.50"},{"v":-1.00854994473506,"d":"-1.01"},1,1,"down","no"]
["ENSG00000273024","INTS4P2","ENST00000614726","NA","NA","NA","NA","integrator complex subunit 4 pseudogene 2 [Source:HGNC Symbol;Acc:HGNC:22351]",{"v":0.097816,"d":"0.10"},{"v":0.061918,"d":"0.06"},{"v":1.57976678833296,"d":"1.58"},{"v":0.659711597548828,"d":"0.66"},1,1,"up","no"]
["ENSG00000107165","TYRP1","ENST00000388918","GO:0055114(oxidation-reduction process);GO:0005507(copper ion binding);GO:0016716(oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen);GO:0042438(melanin biosynthetic process);GO:0033162(melanosome membrane);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0046872(metal ion binding);GO:0004497(monooxygenase activity);GO:0016491(oxidoreductase activity);GO:0008152(metabolic process);GO:0042803(protein homodimerization activity);GO:0005515(protein binding);GO:0042470(melanosome);GO:0010008(endosome membrane);GO:0046982(protein heterodimerization activity);GO:0006582(melanin metabolic process);GO:0030318(melanocyte differentiation);GO:0032438(melanosome organization);GO:0043438(acetoacetic acid metabolic process);GO:0043473(pigmentation);GO:0048023(positive regulation of melanin biosynthetic process);GO:0030669(clathrin-coated endocytic vesicle membrane)","00350(Tyrosine metabolism);04916(Melanogenesis)","K00506","EC:1.14.18.-","tyrosinase related protein 1 [Source:HGNC Symbol;Acc:HGNC:12450]",0,0,1,0,1,1,"no","no"]
["ENSG00000165891","E2F7","ENST00000322886;ENST00000551058;ENST00000552907","GO:0005634(nucleus);GO:0016607(nuclear speck);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0005515(protein binding);GO:0006974(cellular response to DNA damage stimulus);GO:0007049(cell cycle);GO:0005667(transcription factor complex);GO:0042802(identical protein binding);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0001047(core promoter binding);GO:0003714(transcription corepressor activity);GO:0001890(placenta development);GO:0002040(sprouting angiogenesis);GO:0006977(DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest);GO:0032466(negative regulation of cytokinesis);GO:0032877(positive regulation of DNA endoreduplication);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0060707(trophoblast giant cell differentiation);GO:0060718(chorionic trophoblast cell differentiation);GO:0070365(hepatocyte differentiation);GO:0005654(nucleoplasm);GO:0008285(negative regulation of cell proliferation);GO:0030330(DNA damage response, signal transduction by p53 class mediator);GO:2000134(negative regulation of G1/S transition of mitotic cell cycle);GO:0000977(RNA polymerase II regulatory region sequence-specific DNA binding);GO:0001227(transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding);GO:0071930(negative regulation of transcription involved in G1/S transition of mitotic cell cycle);GO:0071930(negative regulation of transcription involved in G1/S transition of mitotic cell cycle)","NA","NA","NA","E2F transcription factor 7 [Source:HGNC Symbol;Acc:HGNC:23820]",{"v":0.033571230842456,"d":"0.03"},{"v":0.0218699190861495,"d":"0.02"},{"v":1.53504138310768,"d":"1.54"},{"v":0.61827754966676,"d":"0.62"},1,1,"up","no"]
["ENSG00000244184","AC091153.3","ENST00000497885","NA","NA","NA","NA",null,{"v":0.105461,"d":"0.11"},{"v":0.433786,"d":"0.43"},{"v":0.24311757410336,"d":"0.24"},{"v":-2.04027391046615,"d":"-2.04"},1,1,"down","no"]
["MSTRG.12967","MIR6835","ENST00000621552","NA","NA","NA","NA","microRNA 6835 [Source:HGNC Symbol;Acc:HGNC:49963]",{"v":0.247141,"d":"0.25"},{"v":0.257903,"d":"0.26"},{"v":0.958271132945332,"d":"0.96"},{"v":-0.0614941854678887,"d":"-0.06"},1,1,"down","no"]
["ENSG00000103546","SLC6A2","ENST00000379906","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0046872(metal ion binding);GO:0005887(integral component of plasma membrane);GO:0015293(symporter activity);GO:0055085(transmembrane transport);GO:0005886(plasma membrane);GO:0005328(neurotransmitter:sodium symporter activity);GO:0006836(neurotransmitter transport);GO:0005515(protein binding);GO:0043005(neuron projection);GO:0007268(chemical synaptic transmission);GO:0005333(norepinephrine transmembrane transporter activity);GO:0015874(norepinephrine transport);GO:0005334(norepinephrine:sodium symporter activity);GO:0008504(monoamine transmembrane transporter activity);GO:0015844(monoamine transport);GO:0043014(alpha-tubulin binding);GO:0048487(beta-tubulin binding);GO:0042493(response to drug);GO:0048265(response to pain);GO:0009986(cell surface);GO:0045121(membrane raft)","NA","NA","NA","solute carrier family 6 member 2 [Source:HGNC Symbol;Acc:HGNC:11048]",0,0,1,0,1,1,"no","no"]
["ENSG00000185272","RBM11","ENST00000468788;ENST00000475864;ENST00000468643","GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0006397(mRNA processing);GO:0008380(RNA splicing);GO:0005634(nucleus);GO:0016607(nuclear speck);GO:0005654(nucleoplasm);GO:0005515(protein binding);GO:0007275(multicellular organism development);GO:0030154(cell differentiation);GO:0042803(protein homodimerization activity);GO:0034599(cellular response to oxidative stress);GO:0008266(poly(U) RNA binding);GO:0000381(regulation of alternative mRNA splicing, via spliceosome);GO:0000381(regulation of alternative mRNA splicing, via spliceosome)","NA","NA","NA","RNA binding motif protein 11 [Source:HGNC Symbol;Acc:HGNC:9897]",{"v":0.115139891525424,"d":"0.12"},{"v":0.0216356372881356,"d":"0.02"},{"v":5.3217702807656,"d":"5.32"},{"v":2.41190623641179,"d":"2.41"},1,1,"up","no"]
["ENSG00000277357","NPAP1P7","ENST00000613027","NA","NA","NA","NA","nuclear pore associated protein 1 pseudogene 7 [Source:HGNC Symbol;Acc:HGNC:51473]",0,0,1,0,1,1,"no","no"]
["ENSG00000270933","AC010719.1","ENST00000602992","NA","NA","NA","NA",null,0,{"v":0.068128,"d":"0.07"},"-inf","-inf",1,1,"down","no"]
["ENSG00000262905","AC015853.1","ENST00000574008","NA","NA","NA","NA",null,{"v":0.088541,"d":"0.09"},0,"inf","inf",1,1,"up","no"]
["MSTRG.10181","AC245452.2","ENST00000435222","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000147488","ST18","ENST00000276480;ENST00000522102","GO:0005634(nucleus);GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0001047(core promoter binding);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0008285(negative regulation of cell proliferation);GO:2001269(positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway);GO:0033209(tumor necrosis factor-mediated signaling pathway);GO:0070498(interleukin-1-mediated signaling pathway);GO:0070102(interleukin-6-mediated signaling pathway);GO:0032993(protein-DNA complex);GO:0032993(protein-DNA complex)","NA","NA","NA","ST18, C2H2C-type zinc finger [Source:HGNC Symbol;Acc:HGNC:18695]",{"v":0.00737961774103918,"d":"0.01"},{"v":0.0156272265212559,"d":"0.02"},{"v":0.472228244148221,"d":"0.47"},{"v":-1.08244376260929,"d":"-1.08"},1,1,"down","no"]
["ENSG00000215187","FAM166B","ENST00000478246;ENST00000619051","NA","NA","NA","NA","family with sequence similarity 166 member B [Source:HGNC Symbol;Acc:HGNC:34242]",0,{"v":0.037093416909621,"d":"0.04"},"-inf","-inf",1,1,"down","no"]
["MSTRG.8753","LINC00309","ENST00000431020","NA","NA","NA","NA","long intergenic non-protein coding RNA 309 [Source:HGNC Symbol;Acc:HGNC:25279]",0,{"v":0.036358,"d":"0.04"},"-inf","-inf",1,1,"down","no"]
["ENSG00000077063","CTTNBP2","ENST00000160373","GO:0005737(cytoplasm);GO:0042995(cell projection);GO:0005938(cell cortex);GO:0043197(dendritic spine);GO:0017124(SH3 domain binding);GO:0007420(brain development);GO:0008021(synaptic vesicle)","NA","NA","NA","cortactin binding protein 2 [Source:HGNC Symbol;Acc:HGNC:15679]",0,{"v":0.0215828017057569,"d":"0.02"},"-inf","-inf",1,1,"down","no"]
["ENSG00000260368","AC027373.1","ENST00000564694","NA","NA","NA","NA",null,{"v":0.137696,"d":"0.14"},{"v":0.133691,"d":"0.13"},{"v":1.02995713997203,"d":"1.03"},{"v":0.0425843031984406,"d":"0.04"},1,1,"up","no"]
["MSTRG.14791",null,"MSTRG.14791.1","NA","NA","NA","NA",null,{"v":0.207202,"d":"0.21"},{"v":0.956929,"d":"0.96"},{"v":0.216528080975705,"d":"0.22"},{"v":-2.20737395835425,"d":"-2.21"},1,1,"down","no"]
["ENSG00000233652","CICP1","ENST00000416803","NA","NA","NA","NA","capicua transcriptional repressor pseudogene 1 [Source:HGNC Symbol;Acc:HGNC:23936]",{"v":0.000942,"d":"0.00"},0,"inf","inf",1,1,"up","no"]
["MSTRG.10087","COL18A1-AS1","ENST00000397787","NA","NA","NA","NA","COL18A1 antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:23132]",0,0,1,0,1,1,"no","no"]
["ENSG00000165023","DIRAS2","ENST00000375765","GO:0016020(membrane);GO:0005525(GTP binding);GO:0000166(nucleotide binding);GO:0007165(signal transduction);GO:0003924(GTPase activity);GO:0005886(plasma membrane)","NA","NA","NA","DIRAS family GTPase 2 [Source:HGNC Symbol;Acc:HGNC:19323]",{"v":0.0113356478873239,"d":"0.01"},0,"inf","inf",1,1,"up","no"]
["ENSG00000175325","PROP1","ENST00000308304","GO:0005634(nucleus);GO:0006355(regulation of transcription, DNA-templated);GO:0006366(transcription from RNA polymerase II promoter);GO:0003677(DNA binding);GO:0043565(sequence-specific DNA binding);GO:0005515(protein binding);GO:0007417(central nervous system development);GO:0000980(RNA polymerase II distal enhancer sequence-specific DNA binding);GO:0001205(transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding);GO:0001206(transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding);GO:0003682(chromatin binding);GO:0008013(beta-catenin binding);GO:0008022(protein C-terminus binding);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0001568(blood vessel development);GO:0009887(animal organ morphogenesis);GO:0009953(dorsal/ventral pattern formation);GO:0016477(cell migration);GO:0021979(hypothalamus cell differentiation);GO:0021984(adenohypophysis development);GO:0043066(negative regulation of apoptotic process);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0048732(gland development);GO:0048850(hypophysis morphogenesis);GO:0060070(canonical Wnt signaling pathway);GO:0060126(somatotropin secreting cell differentiation);GO:0005667(transcription factor complex)","NA","NA","NA","PROP paired-like homeobox 1 [Source:HGNC Symbol;Acc:HGNC:9455]",0,0,1,0,1,1,"no","no"]
["ENSG00000254615","AC027031.2","ENST00000521369;ENST00000577661","NA","NA","NA","NA",null,{"v":0.0374345947850599,"d":"0.04"},{"v":0.394758183227625,"d":"0.39"},{"v":0.0948291799272832,"d":"0.09"},{"v":-3.39852513003131,"d":"-3.40"},1,1,"down","no"]
["MSTRG.2450","AP003733.4","ENST00000623785","NA","NA","NA","NA",null,0,{"v":0.074973,"d":"0.07"},"-inf","-inf",1,1,"down","no"]
["ENSG00000170929","OR1M1","ENST00000429566","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0004930(G-protein coupled receptor activity);GO:0007186(G-protein coupled receptor signaling pathway);GO:0005886(plasma membrane);GO:0004871(signal transducer activity);GO:0007165(signal transduction);GO:0004984(olfactory receptor activity);GO:0007608(sensory perception of smell);GO:0050896(response to stimulus);GO:0050911(detection of chemical stimulus involved in sensory perception of smell)","04740(Olfactory transduction)","K04257","NA","olfactory receptor family 1 subfamily M member 1 [Source:HGNC Symbol;Acc:HGNC:8220]",0,0,1,0,1,1,"no","no"]
["ENSG00000092850","TEKT2","ENST00000469024","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0031514(motile cilium);GO:0005856(cytoskeleton);GO:0042995(cell projection);GO:0005874(microtubule);GO:0005815(microtubule organizing center);GO:0005929(cilium);GO:0030030(cell projection organization);GO:0060271(cilium assembly);GO:0030317(flagellated sperm motility);GO:0060294(cilium movement involved in cell motility);GO:0036126(sperm flagellum);GO:0036159(inner dynein arm assembly)","NA","NA","NA","tektin 2 [Source:HGNC Symbol;Acc:HGNC:11725]",0,{"v":0.0404317846309403,"d":"0.04"},"-inf","-inf",1,1,"down","no"]
["ENSG00000261444","AC106782.4","ENST00000568264","NA","NA","NA","NA",null,{"v":0.175166,"d":"0.18"},0,"inf","inf",1,1,"up","no"]
["ENSG00000268362","AC092279.1","ENST00000594934;ENST00000597683","NA","NA","NA","NA",null,{"v":0.45069661341853,"d":"0.45"},{"v":0.218603162026472,"d":"0.22"},{"v":2.06171131853963,"d":"2.06"},{"v":1.04384234023866,"d":"1.04"},1,1,"up","no"]
["ENSG00000255545","AP004608.1","ENST00000528482;ENST00000533390;ENST00000532886;ENST00000531319","NA","NA","NA","NA",null,{"v":0.0128698273773471,"d":"0.01"},{"v":0.0123300090854028,"d":"0.01"},{"v":1.0437808511093,"d":"1.04"},{"v":0.0618188400629611,"d":"0.06"},1,1,"up","no"]
["ENSG00000283440","AL139352.1","ENST00000255183","NA","NA","NA","NA",null,{"v":0.046989,"d":"0.05"},{"v":0.901624,"d":"0.90"},{"v":0.0521159596461496,"d":"0.05"},{"v":-4.26213094824028,"d":"-4.26"},1,1,"down","no"]
["MSTRG.13722","AC211486.2","ENST00000576046","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000251230","MIR3945HG","ENST00000511703;ENST00000510284","NA","NA","NA","NA","MIR3945 host gene [Source:HGNC Symbol;Acc:HGNC:52002]",{"v":0.582458193711967,"d":"0.58"},{"v":0.533651777890466,"d":"0.53"},{"v":1.09145742194364,"d":"1.09"},{"v":0.126255851493254,"d":"0.13"},1,1,"up","no"]
["MSTRG.11362","CCDC39","ENST00000476379;ENST00000489868;ENST00000473854","GO:0003341(cilium movement);GO:0005930(axoneme);GO:0036159(inner dynein arm assembly);GO:0005737(cytoplasm);GO:0005856(cytoskeleton);GO:0042995(cell projection);GO:0005929(cilium);GO:0001947(heart looping);GO:0030324(lung development);GO:0035469(determination of pancreatic left/right asymmetry);GO:0071907(determination of digestive tract left/right asymmetry);GO:0071910(determination of liver left/right asymmetry);GO:0060287(epithelial cilium movement involved in determination of left/right asymmetry);GO:0060285(cilium-dependent cell motility);GO:0070286(axonemal dynein complex assembly);GO:0003356(regulation of cilium beat frequency);GO:0030317(flagellated sperm motility);GO:0044458(motile cilium assembly);GO:0007368(determination of left/right symmetry);GO:0007507(heart development);GO:0007507(heart development)","NA","NA","NA","coiled-coil domain containing 39 [Source:HGNC Symbol;Acc:HGNC:25244]",{"v":0.0716701983105913,"d":"0.07"},{"v":0.258537448473034,"d":"0.26"},{"v":0.277213992533336,"d":"0.28"},{"v":-1.85092801472475,"d":"-1.85"},1,1,"down","no"]
["ENSG00000163295","ALPI","ENST00000295463","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0046872(metal ion binding);GO:0016787(hydrolase activity);GO:0003824(catalytic activity);GO:0008152(metabolic process);GO:0005886(plasma membrane);GO:0016791(phosphatase activity);GO:0016311(dephosphorylation);GO:0008270(zinc ion binding);GO:0005515(protein binding);GO:0000287(magnesium ion binding);GO:0004035(alkaline phosphatase activity);GO:0031225(anchored component of membrane);GO:0005576(extracellular region);GO:0006501(C-terminal protein lipidation);GO:0007586(digestion);GO:0006654(phosphatidic acid biosynthetic process);GO:0002020(protease binding)","00730(Thiamine metabolism);00790(Folate biosynthesis)","K01077","EC:3.1.3.1","alkaline phosphatase, intestinal [Source:HGNC Symbol;Acc:HGNC:437]",0,0,1,0,1,1,"no","no"]
["ENSG00000215174","NLRP2B","ENST00000434992","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0002376(immune system process);GO:0045087(innate immune response);GO:0032088(negative regulation of NF-kappaB transcription factor activity);GO:0043065(positive regulation of apoptotic process);GO:0045786(negative regulation of cell cycle);GO:0009968(negative regulation of signal transduction);GO:0010804(negative regulation of tumor necrosis factor-mediated signaling pathway);GO:0033137(negative regulation of peptidyl-serine phosphorylation);GO:0034122(negative regulation of toll-like receptor signaling pathway)","NA","NA","NA","NLR family pyrin domain containing 2B [Source:HGNC Symbol;Acc:HGNC:29887]",0,0,1,0,1,1,"no","no"]
["MSTRG.8848","LINC01293","ENST00000453951","NA","NA","NA","NA","long intergenic non-protein coding RNA 1293 [Source:HGNC Symbol;Acc:HGNC:50362]",{"v":0.039221,"d":"0.04"},{"v":0.086521,"d":"0.09"},{"v":0.453311912714832,"d":"0.45"},{"v":-1.14142402016515,"d":"-1.14"},1,1,"down","no"]
["MSTRG.12724","HIST1H4C","ENST00000377803","GO:0005634(nucleus);GO:0003723(RNA binding);GO:0016020(membrane);GO:0003677(DNA binding);GO:0046982(protein heterodimerization activity);GO:0006334(nucleosome assembly);GO:0000786(nucleosome);GO:0005694(chromosome);GO:0005515(protein binding);GO:0006352(DNA-templated transcription, initiation);GO:0005576(extracellular region);GO:0005654(nucleoplasm);GO:0070062(extracellular exosome);GO:0044267(cellular protein metabolic process);GO:1902036(regulation of hematopoietic stem cell differentiation);GO:0043234(protein complex);GO:0000784(nuclear chromosome, telomeric region);GO:0034080(CENP-A containing nucleosome assembly);GO:0031012(extracellular matrix);GO:0045815(positive regulation of gene expression, epigenetic);GO:0019904(protein domain specific binding);GO:0042393(histone binding);GO:1904837(beta-catenin-TCF complex assembly);GO:0045652(regulation of megakaryocyte differentiation);GO:0006335(DNA replication-dependent nucleosome assembly);GO:0006336(DNA replication-independent nucleosome assembly);GO:0000228(nuclear chromosome);GO:0060964(regulation of gene silencing by miRNA);GO:0000183(chromatin silencing at rDNA);GO:0045814(negative regulation of gene expression, epigenetic);GO:0006303(double-strand break repair via nonhomologous end joining);GO:0051290(protein heterotetramerization);GO:0045653(negative regulation of megakaryocyte differentiation);GO:0016233(telomere capping);GO:0032200(telomere organization);GO:0000788(nuclear nucleosome)","05203(Viral carcinogenesis);05322(Systemic lupus erythematosus);05034(Alcoholism)","K11254","NA","histone cluster 1 H4 family member c [Source:HGNC Symbol;Acc:HGNC:4787]",0,0,1,0,1,1,"no","no"]
["ENSG00000271130","IGHV3OR16-8","ENST00000565407","GO:0003823(antigen binding);GO:0034987(immunoglobulin receptor binding);GO:0006910(phagocytosis, recognition);GO:0006911(phagocytosis, engulfment);GO:0006958(complement activation, classical pathway);GO:0042742(defense response to bacterium);GO:0045087(innate immune response);GO:0050853(B cell receptor signaling pathway);GO:0050871(positive regulation of B cell activation);GO:0009897(external side of plasma membrane);GO:0042571(immunoglobulin complex, circulating);GO:0072562(blood microparticle)","NA","NA","NA","immunoglobulin heavy variable 3/OR16-8 (non-functional) [Source:HGNC Symbol;Acc:HGNC:5643]",0,0,1,0,1,1,"no","no"]
["ENSG00000258520","AL359317.1","ENST00000556316","NA","NA","NA","NA",null,{"v":0.020511,"d":"0.02"},0,"inf","inf",1,1,"up","no"]
["ENSG00000279148","AC126474.1","ENST00000623555","NA","NA","NA","NA",null,{"v":0.123384,"d":"0.12"},0,"inf","inf",1,1,"up","no"]
["ENSG00000218336","TENM3","ENST00000510504;ENST00000511685","GO:0016021(integral component of membrane);GO:0007165(signal transduction);GO:0005887(integral component of plasma membrane);GO:0048666(neuron development);GO:0016020(membrane);GO:0007155(cell adhesion);GO:0042803(protein homodimerization activity);GO:0042995(cell projection);GO:0030154(cell differentiation);GO:0097264(self proteolysis);GO:0030424(axon);GO:0043005(neuron projection);GO:0046982(protein heterodimerization activity);GO:0007156(homophilic cell adhesion via plasma membrane adhesion molecules);GO:0050839(cell adhesion molecule binding);GO:0007157(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules);GO:0010976(positive regulation of neuron projection development);GO:0000902(cell morphogenesis);GO:0048593(camera-type eye morphogenesis);GO:0048593(camera-type eye morphogenesis)","NA","NA","NA","teneurin transmembrane protein 3 [Source:HGNC Symbol;Acc:HGNC:29944]",0,0,1,0,1,1,"no","no"]
["ENSG00000263715","LINC02210-CRHR1","ENST00000634540","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0004930(G-protein coupled receptor activity);GO:0007186(G-protein coupled receptor signaling pathway);GO:0004888(transmembrane signaling receptor activity);GO:0007166(cell surface receptor signaling pathway)","NA","NA","NA","LINC02210-CRHR1 readthrough [Source:HGNC Symbol;Acc:HGNC:51483]",{"v":0.0191694153735114,"d":"0.02"},0,"inf","inf",1,1,"up","no"]
["MSTRG.14654","RPL12P25","ENST00000598100","NA","NA","NA","NA","ribosomal protein L12 pseudogene 25 [Source:HGNC Symbol;Acc:HGNC:37008]",{"v":0.019181,"d":"0.02"},0,"inf","inf",1,1,"up","no"]
["ENSG00000227945","AL590006.1","ENST00000417390","NA","NA","NA","NA",null,{"v":0.063271,"d":"0.06"},0,"inf","inf",1,1,"up","no"]
["ENSG00000258212","ZNF75BP","ENST00000546499","NA","NA","NA","NA","zinc finger protein 75B, pseudogene [Source:HGNC Symbol;Acc:HGNC:13147]",0,0,1,0,1,1,"no","no"]
["MSTRG.4387","AL358334.3","ENST00000557343","NA","NA","NA","NA",null,{"v":0.122206,"d":"0.12"},{"v":0.11243,"d":"0.11"},{"v":1.08695188117051,"d":"1.09"},{"v":0.12028807437325,"d":"0.12"},1,1,"up","no"]
["MSTRG.2351","AC010768.2","ENST00000532524","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["MSTRG.8365","SIGLEC22P","ENST00000599104;ENST00000602065","NA","NA","NA","NA","sialic acid binding Ig like lectin 22, pseudogene [Source:HGNC Symbol;Acc:HGNC:15611]",{"v":2.13035390322581,"d":"2.13"},{"v":0.574678510752688,"d":"0.57"},{"v":3.70703595726168,"d":"3.71"},{"v":1.89026610898268,"d":"1.89"},1,1,"up","no"]
["ENSG00000229672","AL450322.2","ENST00000421629","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000230375","GSTA11P","ENST00000452866","NA","NA","NA","NA","glutathione S-transferase alpha 11, pseudogene [Source:HGNC Symbol;Acc:HGNC:49905]",0,0,1,0,1,1,"no","no"]
["ENSG00000231390","SNX18P8","ENST00000455120","NA","NA","NA","NA","sorting nexin 18 pseudogene 8 [Source:HGNC Symbol;Acc:HGNC:39616]",0,0,1,0,1,1,"no","no"]
["ENSG00000245857","GS1-24F4.2","ENST00000500823","NA","NA","NA","NA","uncharacterized LOC100652791 [Source:NCBI gene;Acc:100652791]",0,0,1,0,1,1,"no","no"]
["ENSG00000176826","FKBP9P1","ENST00000441699;ENST00000455909","NA","NA","NA","NA","FK506 binding protein 9 pseudogene 1 [Source:HGNC Symbol;Acc:HGNC:23568]",{"v":0.0151582087912088,"d":"0.02"},{"v":0.0066030989010989,"d":"0.01"},{"v":2.29562043795621,"d":"2.30"},{"v":1.19888412391876,"d":"1.20"},1,1,"up","no"]
["ENSG00000154252","GAL3ST2","ENST00000192314","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016740(transferase activity);GO:0005794(Golgi apparatus);GO:0005515(protein binding);GO:0001733(galactosylceramide sulfotransferase activity);GO:0009247(glycolipid biosynthetic process);GO:0032580(Golgi cisterna membrane);GO:0008150(biological_process);GO:0008146(sulfotransferase activity)","NA","NA","NA","galactose-3-O-sulfotransferase 2 [Source:HGNC Symbol;Acc:HGNC:24869]",0,0,1,0,1,1,"no","no"]
["MSTRG.13070","AL355802.2","ENST00000402069","NA","NA","NA","NA",null,0,{"v":0.158867,"d":"0.16"},"-inf","-inf",1,1,"down","no"]
["ENSG00000249993","BFSP2-AS1","ENST00000515542","NA","NA","NA","NA","BFSP2 antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:28425]",{"v":0.029709,"d":"0.03"},0,"inf","inf",1,1,"up","no"]
["ENSG00000278289","CT45A6","ENST00000620654","NA","NA","NA","NA","cancer/testis antigen family 45 member A6 [Source:HGNC Symbol;Acc:HGNC:33271]",{"v":0.0144975436681223,"d":"0.01"},0,"inf","inf",1,1,"up","no"]
["ENSG00000257171","CR383658.2","ENST00000547576","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["MSTRG.4138","AL355075.2","ENST00000555435","NA","NA","NA","NA",null,{"v":0.714172,"d":"0.71"},{"v":0.358067,"d":"0.36"},{"v":1.99452057855094,"d":"1.99"},{"v":0.99604200856934,"d":"1.00"},1,1,"up","no"]
["MSTRG.1882","AL365273.1","ENST00000433113","NA","NA","NA","NA",null,{"v":1.948323,"d":"1.95"},{"v":0.759157,"d":"0.76"},{"v":2.56642960547028,"d":"2.57"},{"v":1.35976268944709,"d":"1.36"},1,1,"up","no"]
["ENSG00000203581","OR1F2P","ENST00000570470","NA","NA","NA","NA","olfactory receptor family 1 subfamily F member 2 pseudogene [Source:HGNC Symbol;Acc:HGNC:8196]",0,0,1,0,1,1,"no","no"]
["ENSG00000244306","DUXAP10","ENST00000619091;ENST00000624585;ENST00000612696;ENST00000612052;ENST00000614614","NA","NA","NA","NA","double homeobox A pseudogene 10 [Source:NCBI gene;Acc:503639]",0,{"v":0.0024361123910939,"d":"0.00"},"-inf","-inf",1,1,"down","no"]
["ENSG00000262980","OR52L2P","ENST00000572217","NA","NA","NA","NA","olfactory receptor family 52 subfamily L member 2 pseudogene [Source:HGNC Symbol;Acc:HGNC:14788]",0,0,1,0,1,1,"no","no"]
["MSTRG.1336","MFSD4A","ENST00000465651;ENST00000367147;ENST00000478555","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0006810(transport);GO:0055085(transmembrane transport);GO:1904659(glucose transmembrane transport);GO:0005355(glucose transmembrane transporter activity);GO:0005355(glucose transmembrane transporter activity)","NA","NA","NA","major facilitator superfamily domain containing 4A [Source:HGNC Symbol;Acc:HGNC:25433]",{"v":0.106648873056995,"d":"0.11"},{"v":0.101866204663212,"d":"0.10"},{"v":1.04695049167283,"d":"1.05"},{"v":0.0661932215362951,"d":"0.07"},1,1,"up","no"]
["MSTRG.3206","PRB4","ENST00000279575","NA","NA","NA","NA","proline rich protein BstNI subfamily 4 [Source:HGNC Symbol;Acc:HGNC:9340]",0,0,1,0,1,1,"no","no"]
["ENSG00000171401","KRT13","ENST00000468313;ENST00000246635;ENST00000475217","GO:0005634(nucleus);GO:0005198(structural molecule activity);GO:0005515(protein binding);GO:0005882(intermediate filament);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0031424(keratinization);GO:0007010(cytoskeleton organization);GO:0070268(cornification);GO:0045095(keratin filament);GO:0009314(response to radiation);GO:0043587(tongue morphogenesis);GO:0071300(cellular response to retinoic acid);GO:0045111(intermediate filament cytoskeleton);GO:0045111(intermediate filament cytoskeleton)","NA","NA","NA","keratin 13 [Source:HGNC Symbol;Acc:HGNC:6415]",{"v":0.00911767593546172,"d":"0.01"},0,"inf","inf",1,1,"up","no"]
["ENSG00000183010","PYCR1","ENST00000619204;ENST00000577624;ENST00000403172;ENST00000337943","GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0005739(mitochondrion);GO:0005515(protein binding);GO:0008652(cellular amino acid biosynthetic process);GO:0004735(pyrroline-5-carboxylate reductase activity);GO:0006561(proline biosynthetic process);GO:0055129(L-proline biosynthetic process);GO:0042802(identical protein binding);GO:0005759(mitochondrial matrix);GO:0034599(cellular response to oxidative stress);GO:1903206(negative regulation of hydrogen peroxide-induced cell death);GO:0051881(regulation of mitochondrial membrane potential);GO:0051881(regulation of mitochondrial membrane potential)","00330(Arginine and proline metabolism);00330(Arginine and proline metabolism)","K00286","EC:1.5.1.2","pyrroline-5-carboxylate reductase 1 [Source:HGNC Symbol;Acc:HGNC:9721]",{"v":0.109582918918919,"d":"0.11"},{"v":0.166610295564796,"d":"0.17"},{"v":0.657719971910748,"d":"0.66"},{"v":-0.604454615980199,"d":"-0.60"},1,1,"down","no"]
["ENSG00000214653","HNRNPA3P3","ENST00000416838","NA","NA","NA","NA","heterogeneous nuclear ribonucleoprotein A3 pseudogene 3 [Source:HGNC Symbol;Acc:HGNC:39772]",{"v":0.128607,"d":"0.13"},{"v":0.025344,"d":"0.03"},{"v":5.07445549242424,"d":"5.07"},{"v":2.34325302416493,"d":"2.34"},1,1,"up","no"]
["ENSG00000226819","MEIS1-AS3","ENST00000454167","NA","NA","NA","NA","MEIS1 antisense RNA 3 [Source:HGNC Symbol;Acc:HGNC:40369]",0,0,1,0,1,1,"no","no"]
["MSTRG.2833","AP002008.2","ENST00000635926","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["MSTRG.7367","AC132938.3","ENST00000579095;ENST00000578344","NA","NA","NA","NA",null,{"v":0.639146190789474,"d":"0.64"},{"v":0.105909539473684,"d":"0.11"},{"v":6.0348311773019,"d":"6.03"},{"v":2.59331341255841,"d":"2.59"},1,1,"up","no"]
["ENSG00000164385","LINC01600","ENST00000624527","NA","NA","NA","NA","long intergenic non-protein coding RNA 1600 [Source:HGNC Symbol;Acc:HGNC:21600]",0,0,1,0,1,1,"no","no"]
["ENSG00000171435","KSR2","ENST00000339824","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0035556(intracellular signal transduction);GO:0005515(protein binding);GO:0005886(plasma membrane);GO:0005829(cytosol);GO:0004871(signal transducer activity);GO:0043410(positive regulation of MAPK cascade);GO:0019722(calcium-mediated signaling);GO:0005622(intracellular)","04014(Ras signaling pathway)","NA","NA","kinase suppressor of ras 2 [Source:HGNC Symbol;Acc:HGNC:18610]",{"v":0.00290394785175467,"d":"0.00"},0,"inf","inf",1,1,"up","no"]
["ENSG00000253333","AC146944.3","ENST00000509969","NA","NA","NA","NA",null,{"v":0.019438,"d":"0.02"},0,"inf","inf",1,1,"up","no"]
["ENSG00000127564","PKMYT1","ENST00000573944;ENST00000571102;ENST00000575040;ENST00000262300;ENST00000431515;ENST00000574680;ENST00000570649;ENST00000574333;ENST00000574385","GO:0004672(protein kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0016020(membrane);GO:0005794(Golgi apparatus);GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0004674(protein serine/threonine kinase activity);GO:0005634(nucleus);GO:0005730(nucleolus);GO:0016740(transferase activity);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005515(protein binding);GO:0007049(cell cycle);GO:0000139(Golgi membrane);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0000086(G2/M transition of mitotic cell cycle);GO:0010923(negative regulation of phosphatase activity);GO:0007088(regulation of mitotic nuclear division);GO:0000278(mitotic cell cycle);GO:0000079(regulation of cyclin-dependent protein serine/threonine kinase activity);GO:0051726(regulation of cell cycle);GO:0005737(cytoplasm);GO:0005737(cytoplasm)","04110(Cell cycle);04114(Oocyte meiosis);04914(Progesterone-mediated oocyte maturation);04914(Progesterone-mediated oocyte maturation)","K06633","EC:2.7.11.1","protein kinase, membrane associated tyrosine/threonine 1 [Source:HGNC Symbol;Acc:HGNC:29650]",{"v":0.107732864123957,"d":"0.11"},{"v":0.0476729157727453,"d":"0.05"},{"v":2.25983375209343,"d":"2.26"},{"v":1.17621664261727,"d":"1.18"},1,1,"up","no"]
["MSTRG.9156","AC079584.2","ENST00000548756","NA","NA","NA","NA",null,{"v":0.103145,"d":"0.10"},0,"inf","inf",1,1,"up","no"]
["ENSG00000223528","AL359094.1","ENST00000432554","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000228656","MYO5BP3","ENST00000431872","NA","NA","NA","NA","myosin VB pseudogene 3 [Source:HGNC Symbol;Acc:HGNC:38497]",0,0,1,0,1,1,"no","no"]
["MSTRG.5612","AC012676.1","ENST00000574705","NA","NA","NA","NA",null,{"v":0.027255,"d":"0.03"},0,"inf","inf",1,1,"up","no"]
["MSTRG.7887","PODNL1","ENST00000587954;ENST00000538517;ENST00000339560","GO:0005576(extracellular region);GO:0005578(proteinaceous extracellular matrix);GO:0005737(cytoplasm);GO:0004860(protein kinase inhibitor activity);GO:0006469(negative regulation of protein kinase activity);GO:0019221(cytokine-mediated signaling pathway);GO:0046426(negative regulation of JAK-STAT cascade);GO:0031012(extracellular matrix);GO:0031012(extracellular matrix)","NA","NA","NA","podocan like 1 [Source:HGNC Symbol;Acc:HGNC:26275]",{"v":0.0871687428023033,"d":"0.09"},{"v":0.0122104049904031,"d":"0.01"},{"v":7.13889038658542,"d":"7.14"},{"v":2.83569985042039,"d":"2.84"},1,1,"up","no"]
["ENSG00000228541","AC093159.1","ENST00000416845","NA","NA","NA","NA",null,{"v":0.313206,"d":"0.31"},{"v":0.177657,"d":"0.18"},{"v":1.76298147553994,"d":"1.76"},{"v":0.818017315675075,"d":"0.82"},1,1,"up","no"]
["ENSG00000282390","AL392083.1","ENST00000632982","NA","NA","NA","NA",null,0,{"v":0.017049,"d":"0.02"},"-inf","-inf",1,1,"down","no"]
["MSTRG.3673","AC079174.2","ENST00000611145","NA","NA","NA","NA",null,0,{"v":0.075284,"d":"0.08"},"-inf","-inf",1,1,"down","no"]
["MSTRG.13864","AC005070.3","ENST00000607968","NA","NA","NA","NA",null,{"v":0.380438,"d":"0.38"},{"v":0.163357,"d":"0.16"},{"v":2.32887479569287,"d":"2.33"},{"v":1.21963307987147,"d":"1.22"},1,1,"up","no"]
["ENSG00000102935","ZNF423","ENST00000561648","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0005654(nucleoplasm);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0007275(multicellular organism development);GO:0007399(nervous system development);GO:0030154(cell differentiation);GO:0007219(Notch signaling pathway);GO:0045893(positive regulation of transcription, DNA-templated);GO:0045892(negative regulation of transcription, DNA-templated);GO:0030513(positive regulation of BMP signaling pathway)","NA","NA","NA","zinc finger protein 423 [Source:HGNC Symbol;Acc:HGNC:16762]",0,0,1,0,1,1,"no","no"]
["MSTRG.2461","MIR6747","ENST00000617193","NA","NA","NA","NA","microRNA 6747 [Source:HGNC Symbol;Acc:HGNC:50027]",{"v":0.012976,"d":"0.01"},{"v":0.037294,"d":"0.04"},{"v":0.347938006113584,"d":"0.35"},{"v":-1.52309781823825,"d":"-1.52"},1,1,"down","no"]
["ENSG00000268297","CLEC4GP1","ENST00000596555","NA","NA","NA","NA","C-type lectin domain family 4 member G pseudogene 1 [Source:HGNC Symbol;Acc:HGNC:33502]",0,0,1,0,1,1,"no","no"]
["ENSG00000205856","C22orf42","ENST00000467813;ENST00000490640","NA","NA","NA","NA","chromosome 22 open reading frame 42 [Source:HGNC Symbol;Acc:HGNC:27160]",{"v":0.0516981352798054,"d":"0.05"},0,"inf","inf",1,1,"up","no"]
["MSTRG.7739","AC010503.4","ENST00000615487","NA","NA","NA","NA",null,0,{"v":0.147696,"d":"0.15"},"-inf","-inf",1,1,"down","no"]
["ENSG00000278909","AC007608.4","ENST00000623140","NA","NA","NA","NA",null,{"v":0.015786,"d":"0.02"},0,"inf","inf",1,1,"up","no"]
["ENSG00000284042","AC106774.5","ENST00000640558","GO:0005634(nucleus);GO:0046982(protein heterodimerization activity);GO:0006367(transcription initiation from RNA polymerase II promoter)","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["MSTRG.3255","AC053513.1","ENST00000543604","NA","NA","NA","NA",null,{"v":0.097649,"d":"0.10"},{"v":0.114845,"d":"0.11"},{"v":0.850267752187731,"d":"0.85"},{"v":-0.234010872547782,"d":"-0.23"},1,1,"down","no"]
["ENSG00000169668","BCRP2","ENST00000624908;ENST00000398241","NA","NA","NA","NA","breakpoint cluster region pseudogene 2 [Source:HGNC Symbol;Acc:HGNC:1015]",{"v":0.0779845379107766,"d":"0.08"},{"v":0.0552092748301818,"d":"0.06"},{"v":1.41252603209604,"d":"1.41"},{"v":0.4982774558675,"d":"0.50"},1,1,"up","no"]
["ENSG00000278588","HIST1H2BI","ENST00000377733","GO:0005634(nucleus);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0003677(DNA binding);GO:0046982(protein heterodimerization activity);GO:0006334(nucleosome assembly);GO:0000786(nucleosome);GO:0005694(chromosome);GO:0005515(protein binding);GO:0005615(extracellular space);GO:0042742(defense response to bacterium);GO:0016567(protein ubiquitination);GO:0070062(extracellular exosome);GO:0002227(innate immune response in mucosa);GO:0019731(antibacterial humoral response);GO:0050830(defense response to Gram-positive bacterium);GO:0061844(antimicrobial humoral immune response mediated by antimicrobial peptide)","05203(Viral carcinogenesis);05322(Systemic lupus erythematosus);05034(Alcoholism)","K11252","NA","histone cluster 1 H2B family member i [Source:HGNC Symbol;Acc:HGNC:4756]",0,{"v":0.267149,"d":"0.27"},"-inf","-inf",1,1,"down","no"]
["ENSG00000257336","PRELID2P1","ENST00000552837","NA","NA","NA","NA","PRELI domain containing 2 pseudogene 1 [Source:HGNC Symbol;Acc:HGNC:43892]",0,{"v":0.338151,"d":"0.34"},"-inf","-inf",1,1,"down","no"]
["ENSG00000133124","IRS4","ENST00000372129","GO:0016020(membrane);GO:0009967(positive regulation of signal transduction);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0004871(signal transducer activity);GO:0007165(signal transduction);GO:0005158(insulin receptor binding);GO:0005829(cytosol);GO:0008286(insulin receptor signaling pathway);GO:0005070(SH3/SH2 adaptor activity);GO:0043548(phosphatidylinositol 3-kinase binding);GO:0019216(regulation of lipid metabolic process)","04068(FoxO signaling pathway);04022(cGMP - PKG signaling pathway);04152(AMPK signaling pathway);04140(Autophagy - animal);04910(Insulin signaling pathway);04923(Regulation of lipolysis in adipocyte);04920(Adipocytokine signaling pathway);04211(Longevity regulating pathway - mammal);04213(Longevity regulating pathway - multiple species);04930(Type II diabetes mellitus)","K17446","NA","insulin receptor substrate 4 [Source:HGNC Symbol;Acc:HGNC:6128]",0,0,1,0,1,1,"no","no"]
["ENSG00000167968","DNASE1L2","ENST00000564065;ENST00000569184","GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0016787(hydrolase activity);GO:0090305(nucleic acid phosphodiester bond hydrolysis);GO:0005576(extracellular region);GO:0004519(endonuclease activity);GO:0004518(nuclease activity);GO:0004536(deoxyribonuclease activity);GO:0006308(DNA catabolic process);GO:0005634(nucleus);GO:0003677(DNA binding);GO:0006259(DNA metabolic process);GO:0005509(calcium ion binding);GO:0001942(hair follicle development);GO:0003335(corneocyte development);GO:0003335(corneocyte development)","NA","NA","NA","deoxyribonuclease 1 like 2 [Source:HGNC Symbol;Acc:HGNC:2958]",{"v":0.106947,"d":"0.11"},{"v":0.069588,"d":"0.07"},{"v":1.53685980341438,"d":"1.54"},{"v":0.61998556441454,"d":"0.62"},1,1,"up","no"]
["MSTRG.10613","CHKB-AS1","ENST00000380711","NA","NA","NA","NA","CHKB antisense RNA 1 (head to head) [Source:HGNC Symbol;Acc:HGNC:40146]",{"v":0.183806,"d":"0.18"},{"v":0.439949,"d":"0.44"},{"v":0.417789334672883,"d":"0.42"},{"v":-1.25915243113466,"d":"-1.26"},1,1,"down","no"]
["ENSG00000234421","SLC25A5P4","ENST00000418448","NA","NA","NA","NA","solute carrier family 25 member 5 pseudogene 4 [Source:HGNC Symbol;Acc:HGNC:35471]",0,0,1,0,1,1,"no","no"]
["MSTRG.9238","AC078883.3","ENST00000458314;ENST00000417539","NA","NA","NA","NA",null,{"v":0.23556330733519,"d":"0.24"},{"v":0.50228391643454,"d":"0.50"},{"v":0.468984372438869,"d":"0.47"},{"v":-1.09238824502641,"d":"-1.09"},1,1,"down","no"]
["ENSG00000182053","TRIM49B","ENST00000622138","GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0005622(intracellular)","NA","NA","NA","tripartite motif containing 49B [Source:HGNC Symbol;Acc:HGNC:42955]",0,0,1,0,1,1,"no","no"]
["MSTRG.3344","DDN-AS1","ENST00000547866;ENST00000547395","NA","NA","NA","NA","DDN and PRKAG1 antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:53464]",{"v":0.0616355915996425,"d":"0.06"},0,"inf","inf",1,1,"up","no"]
["ENSG00000278080","SPDYE15P","ENST00000424157","NA","NA","NA","NA","speedy/RINGO cell cycle regulator family member E15, pseudogene [Source:HGNC Symbol;Acc:HGNC:51511]",{"v":0.011436,"d":"0.01"},{"v":0.061236,"d":"0.06"},{"v":0.186752890456594,"d":"0.19"},{"v":-2.4207975224746,"d":"-2.42"},1,1,"down","no"]
["ENSG00000198883","PNMA5","ENST00000439251","GO:0005515(protein binding);GO:0042802(identical protein binding);GO:0043065(positive regulation of apoptotic process)","NA","NA","NA","paraneoplastic Ma antigen family member 5 [Source:HGNC Symbol;Acc:HGNC:18743]",{"v":0.00767233381797034,"d":"0.01"},{"v":0.0147981119511486,"d":"0.01"},{"v":0.518467074941599,"d":"0.52"},{"v":-0.947675720750895,"d":"-0.95"},1,1,"down","no"]
["ENSG00000141431","ASXL3","ENST00000269197","GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding)","NA","NA","NA","additional sex combs like 3, transcriptional regulator [Source:HGNC Symbol;Acc:HGNC:29357]",{"v":8.3155451366815E-3,"d":"0.01"},0,"inf","inf",1,1,"up","no"]
["ENSG00000231171","LINC01098","ENST00000507870","NA","NA","NA","NA","long intergenic non-protein coding RNA 1098 [Source:HGNC Symbol;Acc:HGNC:27731]",0,0,1,0,1,1,"no","no"]
["ENSG00000235855","AP003385.2","ENST00000524910","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000234969","AL627389.1","ENST00000413508","NA","NA","NA","NA",null,{"v":0.089435,"d":"0.09"},0,"inf","inf",1,1,"up","no"]
["ENSG00000225094","SETP20","ENST00000457046","NA","NA","NA","NA","SET pseudogene 20 [Source:HGNC Symbol;Acc:HGNC:42939]",0,0,1,0,1,1,"no","no"]
["ENSG00000259496","AC021818.2","ENST00000560960","NA","NA","NA","NA",null,0,{"v":0.208628,"d":"0.21"},"-inf","-inf",1,1,"down","no"]
["ENSG00000180044","C3orf80","ENST00000326474","GO:0016020(membrane);GO:0016021(integral component of membrane)","NA","NA","NA","chromosome 3 open reading frame 80 [Source:HGNC Symbol;Acc:HGNC:40048]",0,{"v":0.0558,"d":"0.06"},"-inf","-inf",1,1,"down","no"]
["ENSG00000228958","PIGPP3","ENST00000425307","NA","NA","NA","NA","phosphatidylinositol glycan anchor biosynthesis class P pseudogene 3 [Source:HGNC Symbol;Acc:HGNC:45155]",0,0,1,0,1,1,"no","no"]
["ENSG00000054179","ENTPD2","ENST00000355097;ENST00000460614","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0016787(hydrolase activity);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005886(plasma membrane);GO:0070062(extracellular exosome);GO:0034656(nucleobase-containing small molecule catabolic process);GO:0017111(nucleoside-triphosphatase activity);GO:0017110(nucleoside-diphosphatase activity);GO:0007186(G-protein coupled receptor signaling pathway);GO:0009181(purine ribonucleoside diphosphate catabolic process);GO:0030168(platelet activation);GO:0005605(basal lamina);GO:0005605(basal lamina)","00230(Purine metabolism);04742(Taste transduction);04742(Taste transduction)","K01509","EC:3.6.1.3","ectonucleoside triphosphate diphosphohydrolase 2 [Source:HGNC Symbol;Acc:HGNC:3364]",{"v":0.269551811241929,"d":"0.27"},{"v":0.355848243828333,"d":"0.36"},{"v":0.757490913379258,"d":"0.76"},{"v":-0.400699512310103,"d":"-0.40"},1,1,"down","no"]
["MSTRG.11129","MTCO1P29","ENST00000496868","NA","NA","NA","NA","mitochondrially encoded cytochrome c oxidase I pseudogene 29 [Source:HGNC Symbol;Acc:HGNC:52094]",{"v":0.184444,"d":"0.18"},0,"inf","inf",1,1,"up","no"]
["MSTRG.15453","GPC3","ENST00000370818","GO:0016020(membrane);GO:0005886(plasma membrane);GO:0005576(extracellular region);GO:0005615(extracellular space);GO:0005578(proteinaceous extracellular matrix);GO:0031225(anchored component of membrane);GO:0043395(heparan sulfate proteoglycan binding);GO:0030414(peptidase inhibitor activity);GO:0010466(negative regulation of peptidase activity);GO:0005515(protein binding);GO:0070062(extracellular exosome);GO:0044267(cellular protein metabolic process);GO:0043687(post-translational protein modification);GO:0005887(integral component of plasma membrane);GO:0005788(endoplasmic reticulum lumen);GO:0009653(anatomical structure morphogenesis);GO:0043202(lysosomal lumen);GO:0001523(retinoid metabolic process);GO:0006024(glycosaminoglycan biosynthetic process);GO:0006027(glycosaminoglycan catabolic process);GO:0030203(glycosaminoglycan metabolic process);GO:0005796(Golgi lumen);GO:0072138(mesenchymal cell proliferation involved in ureteric bud development);GO:0060422(peptidyl-dipeptidase inhibitor activity);GO:0001658(branching involved in ureteric bud morphogenesis);GO:0001822(kidney development);GO:0008285(negative regulation of cell proliferation);GO:0009887(animal organ morphogenesis);GO:0009948(anterior/posterior axis specification);GO:0010171(body morphogenesis);GO:0030282(bone mineralization);GO:0030316(osteoclast differentiation);GO:0030324(lung development);GO:0030513(positive regulation of BMP signaling pathway);GO:0035116(embryonic hindlimb morphogenesis);GO:0040008(regulation of growth);GO:0045732(positive regulation of protein catabolic process);GO:0045807(positive regulation of endocytosis);GO:0045879(negative regulation of smoothened signaling pathway);GO:0045880(positive regulation of smoothened signaling pathway);GO:0045926(negative regulation of growth);GO:0046326(positive regulation of glucose import);GO:0050680(negative regulation of epithelial cell proliferation);GO:0060976(coronary vasculature development);GO:0072111(cell proliferation involved in kidney development);GO:0072180(mesonephric duct morphogenesis);GO:0072203(cell proliferation involved in metanephros development);GO:0090090(negative regulation of canonical Wnt signaling pathway);GO:2000096(positive regulation of Wnt signaling pathway, planar cell polarity pathway);GO:0005764(lysosome);GO:0046658(anchored component of plasma membrane)","05205(Proteoglycans in cancer)","K08109","NA","glypican 3 [Source:HGNC Symbol;Acc:HGNC:4451]",{"v":0.0192699461453338,"d":"0.02"},{"v":0.0375443305053486,"d":"0.04"},{"v":0.513258483663428,"d":"0.51"},{"v":-0.962242526010858,"d":"-0.96"},1,1,"down","no"]
["ENSG00000086991","NOX4","ENST00000424319","GO:0005634(nucleus);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0000166(nucleotide binding);GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0030054(cell junction);GO:0050660(flavin adenine dinucleotide binding);GO:0005730(nucleolus);GO:0005925(focal adhesion);GO:0006954(inflammatory response);GO:0020037(heme binding);GO:0008285(negative regulation of cell proliferation);GO:0009055(electron carrier activity);GO:0034599(cellular response to oxidative stress);GO:0007569(cell aging);GO:0016174(NAD(P)H oxidase activity);GO:0072593(reactive oxygen species metabolic process);GO:0016175(superoxide-generating NADPH oxidase activity);GO:0000902(cell morphogenesis);GO:0042554(superoxide anion generation);GO:0072341(modified amino acid binding);GO:0050667(homocysteine metabolic process);GO:0019826(oxygen sensor activity);GO:0006801(superoxide metabolic process);GO:0010467(gene expression);GO:0050664(oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor);GO:0001666(response to hypoxia);GO:0007568(aging);GO:0014911(positive regulation of smooth muscle cell migration);GO:0043065(positive regulation of apoptotic process);GO:0043406(positive regulation of MAP kinase activity);GO:0045453(bone resorption);GO:0051496(positive regulation of stress fiber assembly);GO:0051897(positive regulation of protein kinase B signaling);GO:0055007(cardiac muscle cell differentiation);GO:0070374(positive regulation of ERK1 and ERK2 cascade);GO:0071320(cellular response to cAMP);GO:0071333(cellular response to glucose stimulus);GO:0071480(cellular response to gamma radiation);GO:0071560(cellular response to transforming growth factor beta stimulus);GO:2000379(positive regulation of reactive oxygen species metabolic process);GO:2000573(positive regulation of DNA biosynthetic process);GO:0001725(stress fiber);GO:0005739(mitochondrion);GO:0016324(apical plasma membrane);GO:0043020(NADPH oxidase complex);GO:0048471(perinuclear region of cytoplasm);GO:0071944(cell periphery)","04933(AGE-RAGE signaling pathway in diabetic complications)","K21423","EC:1.6.3.-","NADPH oxidase 4 [Source:HGNC Symbol;Acc:HGNC:7891]",0,0,1,0,1,1,"no","no"]
["ENSG00000251287","ALG1L2","ENST00000511726;ENST00000425059","GO:0016740(transferase activity);GO:0016757(transferase activity, transferring glycosyl groups);GO:0000030(mannosyltransferase activity);GO:0097502(mannosylation);GO:0005783(endoplasmic reticulum);GO:0006486(protein glycosylation);GO:0006486(protein glycosylation)","NA","NA","NA","ALG1, chitobiosyldiphosphodolichol beta-mannosyltransferase like 2 [Source:HGNC Symbol;Acc:HGNC:37258]",{"v":0.26359899066044,"d":"0.26"},{"v":0.0977655710473649,"d":"0.10"},{"v":2.6962353703507,"d":"2.70"},{"v":1.43094644340993,"d":"1.43"},1,1,"up","no"]
["ENSG00000152611","CAPSL","ENST00000397367","GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0005509(calcium ion binding)","NA","NA","NA","calcyphosine like [Source:HGNC Symbol;Acc:HGNC:28375]",0,0,1,0,1,1,"no","no"]
["ENSG00000072041","SLC6A15","ENST00000450363;ENST00000266682","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005887(integral component of plasma membrane);GO:0015293(symporter activity);GO:0055085(transmembrane transport);GO:0006811(ion transport);GO:0003333(amino acid transmembrane transport);GO:0006814(sodium ion transport);GO:0005328(neurotransmitter:sodium symporter activity);GO:0006836(neurotransmitter transport);GO:0005886(plasma membrane);GO:0006865(amino acid transport);GO:0015171(amino acid transmembrane transporter activity);GO:0015804(neutral amino acid transport);GO:0015824(proline transport);GO:0035524(proline transmembrane transport);GO:0005326(neurotransmitter transporter activity);GO:0015820(leucine transport);GO:0005298(proline:sodium symporter activity);GO:0005298(proline:sodium symporter activity)","NA","NA","NA","solute carrier family 6 member 15 [Source:HGNC Symbol;Acc:HGNC:13621]",0,0,1,0,1,1,"no","no"]
["MSTRG.3110","RPS3AP43","ENST00000479743","NA","NA","NA","NA","ribosomal protein S3a pseudogene 43 [Source:HGNC Symbol;Acc:HGNC:36684]",0,0,1,0,1,1,"no","no"]
["ENSG00000180638","SLC47A2","ENST00000456947;ENST00000463318;ENST00000467609","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0055085(transmembrane transport);GO:0005886(plasma membrane);GO:0015238(drug transmembrane transporter activity);GO:0015297(antiporter activity);GO:0006855(drug transmembrane transport);GO:0015307(drug:proton antiporter activity);GO:0046618(drug export);GO:0046618(drug export)","NA","NA","NA","solute carrier family 47 member 2 [Source:HGNC Symbol;Acc:HGNC:26439]",{"v":0.0065839209385742,"d":"0.01"},{"v":7.60605320579883E-3,"d":"0.01"},{"v":0.86561594567267,"d":"0.87"},{"v":-0.208201019323609,"d":"-0.21"},1,1,"down","no"]
["ENSG00000235454","HAUS6P3","ENST00000456660","NA","NA","NA","NA","HAUS augmin like complex subunit 6 pseudogene 3 [Source:HGNC Symbol;Acc:HGNC:50772]",{"v":0.047985,"d":"0.05"},{"v":0.045059,"d":"0.05"},{"v":1.06493708249184,"d":"1.06"},{"v":0.0907681971568776,"d":"0.09"},1,1,"up","no"]
["ENSG00000099812","MISP","ENST00000215582","GO:0005737(cytoplasm);GO:0043231(intracellular membrane-bounded organelle);GO:0003779(actin binding);GO:0051301(cell division);GO:0005886(plasma membrane);GO:0005925(focal adhesion);GO:0005856(cytoskeleton);GO:0007049(cell cycle);GO:0030054(cell junction);GO:0005938(cell cortex)","NA","NA","NA","mitotic spindle positioning [Source:HGNC Symbol;Acc:HGNC:27000]",0,0,1,0,1,1,"no","no"]
["ENSG00000138075","ABCG5","ENST00000260645","GO:0042632(cholesterol homeostasis);GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0005515(protein binding);GO:0016887(ATPase activity);GO:0005886(plasma membrane);GO:0042626(ATPase activity, coupled to transmembrane movement of substances);GO:0055085(transmembrane transport);GO:0046982(protein heterodimerization activity);GO:0043235(receptor complex);GO:0033344(cholesterol efflux);GO:0006855(drug transmembrane transport);GO:0016324(apical plasma membrane);GO:0030299(intestinal cholesterol absorption);GO:0017127(cholesterol transporter activity);GO:0007588(excretion);GO:0010949(negative regulation of intestinal phytosterol absorption);GO:0045796(negative regulation of intestinal cholesterol absorption);GO:0043190(ATP-binding cassette (ABC) transporter complex);GO:0007584(response to nutrient);GO:0010212(response to ionizing radiation);GO:0042493(response to drug);GO:0045177(apical part of cell)","02010(ABC transporters);04976(Bile secretion);04975(Fat digestion and absorption);04979(Cholesterol metabolism)","K05683","NA","ATP binding cassette subfamily G member 5 [Source:HGNC Symbol;Acc:HGNC:13886]",0,0,1,0,1,1,"no","no"]
["ENSG00000137673","MMP7","ENST00000533366","GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0016787(hydrolase activity);GO:0005515(protein binding);GO:0008233(peptidase activity);GO:0006508(proteolysis);GO:0005576(extracellular region);GO:0005578(proteinaceous extracellular matrix);GO:0004222(metalloendopeptidase activity);GO:0008237(metallopeptidase activity);GO:0031012(extracellular matrix);GO:0004252(serine-type endopeptidase activity);GO:0070062(extracellular exosome);GO:0030574(collagen catabolic process);GO:0005615(extracellular space);GO:0022617(extracellular matrix disassembly);GO:0008201(heparin binding);GO:0007568(aging);GO:0031667(response to nutrient levels);GO:0044849(estrous cycle);GO:0060135(maternal process involved in female pregnancy);GO:0071260(cellular response to mechanical stimulus);GO:0009986(cell surface)","04310(Wnt signaling pathway)","NA","NA","matrix metallopeptidase 7 [Source:HGNC Symbol;Acc:HGNC:7174]",0,0,1,0,1,1,"no","no"]
["ENSG00000229145","ACTBP1","ENST00000417985","NA","NA","NA","NA","actin, beta pseudogene 1 [Source:HGNC Symbol;Acc:HGNC:134]",0,0,1,0,1,1,"no","no"]
["ENSG00000215177","IGLV8OR8-1","ENST00000399730","NA","NA","NA","NA","immunoglobulin lambda variable 8/OR8-1 (pseudogene) [Source:HGNC Symbol;Acc:HGNC:5932]",0,0,1,0,1,1,"no","no"]
["ENSG00000261222","AC064805.1","ENST00000581412;ENST00000577560;ENST00000569279","NA","NA","NA","NA",null,{"v":0.118853855080511,"d":"0.12"},{"v":0.238235766240977,"d":"0.24"},{"v":0.498891736349485,"d":"0.50"},{"v":-1.00320132216631,"d":"-1.00"},1,1,"down","no"]
["ENSG00000169962","TAS1R3","ENST00000339381","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0004930(G-protein coupled receptor activity);GO:0007186(G-protein coupled receptor signaling pathway);GO:0005886(plasma membrane);GO:0004871(signal transducer activity);GO:0007165(signal transduction);GO:0050896(response to stimulus);GO:0050909(sensory perception of taste);GO:0046982(protein heterodimerization activity);GO:0008527(taste receptor activity);GO:0033041(sweet taste receptor activity);GO:0001582(detection of chemical stimulus involved in sensory perception of sweet taste);GO:0050916(sensory perception of sweet taste);GO:0050917(sensory perception of umami taste);GO:1903767(sweet taste receptor complex)","04973(Carbohydrate digestion and absorption);04742(Taste transduction)","K04626","NA","taste 1 receptor member 3 [Source:HGNC Symbol;Acc:HGNC:15661]",{"v":0.162316,"d":"0.16"},{"v":0.207,"d":"0.21"},{"v":0.784135265700483,"d":"0.78"},{"v":-0.350825549829296,"d":"-0.35"},1,1,"down","no"]
["ENSG00000281477","LINC01955","ENST00000626392","NA","NA","NA","NA","long intergenic non-protein coding RNA 1955 [Source:HGNC Symbol;Acc:HGNC:52780]",{"v":0.165749,"d":"0.17"},{"v":0.030639,"d":"0.03"},{"v":5.40973922125396,"d":"5.41"},{"v":2.43555905000929,"d":"2.44"},1,1,"up","no"]
["MSTRG.2582","CNIH2","ENST00000528852;ENST00000311445;ENST00000534826","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0006810(transport);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005886(plasma membrane);GO:0042995(cell projection);GO:0030054(cell junction);GO:0045202(synapse);GO:0045211(postsynaptic membrane);GO:0030425(dendrite);GO:0000139(Golgi membrane);GO:0005515(protein binding);GO:0014069(postsynaptic density);GO:0043197(dendritic spine);GO:0006888(ER to Golgi vesicle-mediated transport);GO:0048208(COPII vesicle coating);GO:0012507(ER to Golgi transport vesicle membrane);GO:0033116(endoplasmic reticulum-Golgi intermediate compartment membrane);GO:2000311(regulation of AMPA receptor activity);GO:0032281(AMPA glutamate receptor complex);GO:0043198(dendritic shaft);GO:0035249(synaptic transmission, glutamatergic);GO:0042391(regulation of membrane potential);GO:0051668(localization within membrane);GO:1902684(negative regulation of receptor localization to synapse);GO:1903743(negative regulation of anterograde synaptic vesicle transport);GO:2000310(regulation of NMDA receptor activity);GO:2000310(regulation of NMDA receptor activity)","NA","NA","NA","cornichon family AMPA receptor auxiliary protein 2 [Source:HGNC Symbol;Acc:HGNC:28744]",{"v":0.0872285161913968,"d":"0.09"},{"v":0.012939636539391,"d":"0.01"},{"v":6.74118750753583,"d":"6.74"},{"v":2.7530027546604,"d":"2.75"},1,1,"up","no"]
["ENSG00000231122","FAM25E","ENST00000411791","NA","NA","NA","NA","family with sequence similarity 25 member E [Source:HGNC Symbol;Acc:HGNC:23587]",0,0,1,0,1,1,"no","no"]
["ENSG00000198488","B3GNT6","ENST00000622824","GO:0016020(membrane);GO:0016757(transferase activity, transferring glycosyl groups);GO:0006486(protein glycosylation);GO:0005794(Golgi apparatus);GO:0000139(Golgi membrane);GO:0008378(galactosyltransferase activity);GO:0016021(integral component of membrane);GO:0016740(transferase activity);GO:0016266(O-glycan processing);GO:0009101(glycoprotein biosynthetic process);GO:0008499(UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity);GO:0047223(beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase activity);GO:0047224(acetylgalactosaminyl-O-glycosyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase activity);GO:0016269(O-glycan processing, core 3)","00512(Mucin type O-glycan biosynthesis)","K00739","EC:2.4.1.147","UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 6 [Source:HGNC Symbol;Acc:HGNC:24141]",0,0,1,0,1,1,"no","no"]
["ENSG00000234749","FAM90A21P","ENST00000510875","NA","NA","NA","NA","family with sequence similarity 90 member A21, pseudogene [Source:HGNC Symbol;Acc:HGNC:32269]",{"v":0.027657,"d":"0.03"},0,"inf","inf",1,1,"up","no"]
["ENSG00000280604","AJ239328.1","ENST00000626237","NA","NA","NA","NA",null,{"v":0.04025,"d":"0.04"},{"v":0.019013,"d":"0.02"},{"v":2.11697259769631,"d":"2.12"},{"v":1.08200259507838,"d":"1.08"},1,1,"up","no"]
["ENSG00000176236","C10orf111","ENST00000624760","NA","NA","NA","NA","chromosome 10 open reading frame 111 [Source:HGNC Symbol;Acc:HGNC:28582]",{"v":0.050878,"d":"0.05"},{"v":0.044538,"d":"0.04"},{"v":1.14235035250797,"d":"1.14"},{"v":0.192005185121293,"d":"0.19"},1,1,"up","no"]
["ENSG00000276637","AC084851.3","ENST00000432771","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000185053","SGCZ","ENST00000382080","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005886(plasma membrane);GO:0005856(cytoskeleton);GO:0016012(sarcoglycan complex);GO:0042383(sarcolemma);GO:0055001(muscle cell development);GO:0046716(muscle cell cellular homeostasis);GO:0048738(cardiac muscle tissue development);GO:0060047(heart contraction);GO:0007517(muscle organ development);GO:0061024(membrane organization)","NA","NA","NA","sarcoglycan zeta [Source:HGNC Symbol;Acc:HGNC:14075]",0,0,1,0,1,1,"no","no"]
["ENSG00000024526","DEPDC1","ENST00000456315;ENST00000370966","GO:0005634(nucleus);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0035556(intracellular signal transduction);GO:0007165(signal transduction);GO:0043547(positive regulation of GTPase activity);GO:0005096(GTPase activator activity);GO:0005515(protein binding);GO:0045892(negative regulation of transcription, DNA-templated);GO:0017053(transcriptional repressor complex);GO:0017053(transcriptional repressor complex)","NA","NA","NA","DEP domain containing 1 [Source:HGNC Symbol;Acc:HGNC:22949]",{"v":0.0179948338414634,"d":"0.02"},{"v":0.0603105492886179,"d":"0.06"},{"v":0.298369589627655,"d":"0.30"},{"v":-1.74482759390916,"d":"-1.74"},1,1,"down","no"]
["MSTRG.6193","AC040169.3","ENST00000622369","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000248668","OXCT1-AS1","ENST00000508458","NA","NA","NA","NA","OXCT1 antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:40423]",0,{"v":0.0404358246973366,"d":"0.04"},"-inf","-inf",1,1,"down","no"]
["ENSG00000281627","DUX4L3","ENST00000630187","NA","NA","NA","NA","double homeobox 4 like 3 [Source:HGNC Symbol;Acc:HGNC:38688]",0,0,1,0,1,1,"no","no"]
["ENSG00000251603","AC092611.2","ENST00000508664","NA","NA","NA","NA",null,{"v":0.009258,"d":"0.01"},0,"inf","inf",1,1,"up","no"]
["MSTRG.3571","AC073569.2","ENST00000551995","NA","NA","NA","NA",null,{"v":0.092412,"d":"0.09"},0,"inf","inf",1,1,"up","no"]
["ENSG00000254990","AP001781.2","ENST00000529841;ENST00000534218","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000284689","AC097493.5","ENST00000641103","NA","NA","NA","NA",null,{"v":0.026123,"d":"0.03"},0,"inf","inf",1,1,"up","no"]
["MSTRG.12507","AC008676.2","ENST00000509655;ENST00000519499","NA","NA","NA","NA",null,{"v":0.0360895137580098,"d":"0.04"},0,"inf","inf",1,1,"up","no"]
["ENSG00000120160","EQTN","ENST00000380032","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0006897(endocytosis);GO:0005886(plasma membrane);GO:0031410(cytoplasmic vesicle);GO:0002081(outer acrosomal membrane);GO:0002080(acrosomal membrane);GO:0002079(inner acrosomal membrane);GO:0007342(fusion of sperm to egg plasma membrane);GO:0060478(acrosomal vesicle exocytosis);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005769(early endosome)","NA","NA","NA","equatorin [Source:HGNC Symbol;Acc:HGNC:1359]",0,0,1,0,1,1,"no","no"]
["ENSG00000236848","RPL23AP95","ENST00000426806","NA","NA","NA","NA","ribosomal protein L23a pseudogene 95 [Source:HGNC Symbol;Acc:HGNC:51630]",0,0,1,0,1,1,"no","no"]
["ENSG00000229205","LINC00200","ENST00000425630","NA","NA","NA","NA","long intergenic non-protein coding RNA 200 [Source:HGNC Symbol;Acc:HGNC:30974]",{"v":0.239477200429492,"d":"0.24"},{"v":0.180156073013601,"d":"0.18"},{"v":1.32927631260819,"d":"1.33"},{"v":0.410641024399792,"d":"0.41"},1,1,"up","no"]
["ENSG00000078018","MAP2","ENST00000199940;ENST00000445941;ENST00000464007;ENST00000478233;ENST00000360351","GO:0005737(cytoplasm);GO:0005730(nucleolus);GO:0005829(cytosol);GO:0005856(cytoskeleton);GO:0042995(cell projection);GO:0005515(protein binding);GO:0015631(tubulin binding);GO:0001578(microtubule bundle formation);GO:0021954(central nervous system neuron development);GO:0005874(microtubule);GO:0030425(dendrite);GO:0005516(calmodulin binding);GO:0008017(microtubule binding);GO:0043005(neuron projection);GO:0005875(microtubule associated complex);GO:0002162(dystroglycan binding);GO:0005198(structural molecule activity);GO:0000226(microtubule cytoskeleton organization);GO:0031175(neuron projection development);GO:0048813(dendrite morphogenesis);GO:0007409(axonogenesis);GO:0016358(dendrite development);GO:0030010(establishment of cell polarity);GO:0050770(regulation of axonogenesis);GO:0071310(cellular response to organic substance);GO:0005622(intracellular);GO:0014069(postsynaptic density);GO:0034399(nuclear periphery);GO:0043025(neuronal cell body);GO:0043198(dendritic shaft);GO:0044297(cell body);GO:0097442(CA3 pyramidal cell dendrite);GO:0097442(CA3 pyramidal cell dendrite)","NA","NA","NA","microtubule associated protein 2 [Source:HGNC Symbol;Acc:HGNC:6839]",{"v":0.0527032766675318,"d":"0.05"},{"v":0.0130164201920581,"d":"0.01"},{"v":4.04898396716544,"d":"4.05"},{"v":2.01755993036021,"d":"2.02"},1,1,"up","no"]
["ENSG00000176320","AL138899.1","ENST00000415019","NA","NA","NA","NA",null,{"v":0.025077,"d":"0.03"},{"v":0.050243,"d":"0.05"},{"v":0.499114304480226,"d":"0.50"},{"v":-1.00255784320793,"d":"-1.00"},1,1,"down","no"]
["ENSG00000241644","INMT","ENST00000461246;ENST00000013222","GO:0005737(cytoplasm);GO:0008168(methyltransferase activity);GO:0016740(transferase activity);GO:0032259(methylation);GO:0005829(cytosol);GO:0005515(protein binding);GO:0009308(amine metabolic process);GO:0009636(response to toxic substance);GO:0004790(thioether S-methyltransferase activity);GO:0030748(amine N-methyltransferase activity);GO:0102707(S-adenosyl-L-methionine:beta-alanine N-methyltransferase activity);GO:0102707(S-adenosyl-L-methionine:beta-alanine N-methyltransferase activity)","00380(Tryptophan metabolism);00450(Selenocompound metabolism);00450(Selenocompound metabolism)","K00562","EC:2.1.1.49;EC:2.1.1.96","indolethylamine N-methyltransferase [Source:HGNC Symbol;Acc:HGNC:6069]",{"v":0.0236017464454976,"d":"0.02"},{"v":0.0150745956753555,"d":"0.02"},{"v":1.56566364722356,"d":"1.57"},{"v":0.64677431058385,"d":"0.65"},1,1,"up","no"]
["ENSG00000272953","AC092171.4","ENST00000609130","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000224963","U82695.1","ENST00000635752","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000268916","CSAG3","ENST00000599845","GO:0042493(response to drug)","NA","NA","NA","CSAG family member 3 [Source:HGNC Symbol;Acc:HGNC:26237]",0,0,1,0,1,1,"no","no"]
["ENSG00000229156","CR769776.2","ENST00000445057","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["MSTRG.9718","TLDC2","ENST00000436941;ENST00000217320;ENST00000602922","NA","NA","NA","NA","TBC/LysM-associated domain containing 2 [Source:HGNC Symbol;Acc:HGNC:16112]",{"v":0.0210824806110458,"d":"0.02"},{"v":1.07453865961614,"d":"1.07"},{"v":0.019620029882012,"d":"0.02"},{"v":-5.6715289509394,"d":"-5.67"},1,1,"down","no"]
["ENSG00000241313","WWTR1-AS1","ENST00000495094","NA","NA","NA","NA","WWTR1 antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:41035]",0,0,1,0,1,1,"no","no"]
["MSTRG.14239","AC107959.2","ENST00000501897","NA","NA","NA","NA",null,{"v":0.356392,"d":"0.36"},{"v":0.140464,"d":"0.14"},{"v":2.53724797812963,"d":"2.54"},{"v":1.3432645282054,"d":"1.34"},1,1,"up","no"]
["ENSG00000175658","DRD5P2","ENST00000421395","NA","NA","NA","NA","dopamine receptor D5 pseudogene 2 [Source:HGNC Symbol;Acc:HGNC:3028]",0,0,1,0,1,1,"no","no"]
["ENSG00000254900","AC091053.2","ENST00000534169","NA","NA","NA","NA",null,{"v":0.007206,"d":"0.01"},0,"inf","inf",1,1,"up","no"]
["ENSG00000235275","KRT18P16","ENST00000510337","NA","NA","NA","NA","keratin 18 pseudogene 16 [Source:HGNC Symbol;Acc:HGNC:33384]",0,0,1,0,1,1,"no","no"]
["ENSG00000251429","AC098679.3","ENST00000513994;ENST00000514881","NA","NA","NA","NA",null,{"v":0.0136200577986726,"d":"0.01"},0,"inf","inf",1,1,"up","no"]
["ENSG00000126251","GPR42","ENST00000597214;ENST00000454971","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0004930(G-protein coupled receptor activity);GO:0007186(G-protein coupled receptor signaling pathway);GO:0005886(plasma membrane);GO:0004871(signal transducer activity);GO:0007165(signal transduction);GO:0005887(integral component of plasma membrane);GO:0005887(integral component of plasma membrane)","NA","NA","NA","G protein-coupled receptor 42 (gene/pseudogene) [Source:HGNC Symbol;Acc:HGNC:4500]",{"v":0.276870303811057,"d":"0.28"},0,"inf","inf",1,1,"up","no"]
["MSTRG.197","AC004824.1","ENST00000439577","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000105707","HPN","ENST00000593305;ENST00000262626","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016787(hydrolase activity);GO:0005789(endoplasmic reticulum membrane);GO:0071805(potassium ion transmembrane transport);GO:0005886(plasma membrane);GO:0008233(peptidase activity);GO:0006508(proteolysis);GO:0004252(serine-type endopeptidase activity);GO:0008236(serine-type peptidase activity);GO:0005887(integral component of plasma membrane);GO:0005515(protein binding);GO:0070008(serine-type exopeptidase activity);GO:0070062(extracellular exosome);GO:0010628(positive regulation of gene expression);GO:0008360(regulation of cell shape);GO:0043066(negative regulation of apoptotic process);GO:0031965(nuclear membrane);GO:0016324(apical plasma membrane);GO:0009986(cell surface);GO:0005911(cell-cell junction);GO:0030307(positive regulation of cell growth);GO:0050680(negative regulation of epithelial cell proliferation);GO:0010719(negative regulation of epithelial to mesenchymal transition);GO:0015269(calcium-activated potassium channel activity);GO:0090103(cochlea morphogenesis);GO:0043025(neuronal cell body);GO:0043923(positive regulation by host of viral transcription);GO:0010756(positive regulation of plasminogen activation);GO:0034769(basement membrane disassembly);GO:0048012(hepatocyte growth factor receptor signaling pathway);GO:0050910(detection of mechanical stimulus involved in sensory perception of sound);GO:0097066(response to thyroid hormone);GO:0097195(pilomotor reflex);GO:2000347(positive regulation of hepatocyte proliferation);GO:2000611(positive regulation of thyroid hormone generation);GO:2000611(positive regulation of thyroid hormone generation)","05203(Viral carcinogenesis);05203(Viral carcinogenesis)","K08665","EC:3.4.21.106","hepsin [Source:HGNC Symbol;Acc:HGNC:5155]",0,0,1,0,1,1,"no","no"]
["ENSG00000274184","AC011815.2","ENST00000618230","NA","NA","NA","NA",null,{"v":0.078852,"d":"0.08"},{"v":0.025182,"d":"0.03"},{"v":3.13128425065523,"d":"3.13"},{"v":1.64675447890033,"d":"1.65"},1,1,"up","no"]
["MSTRG.11214","AC117382.1","ENST00000468074","NA","NA","NA","NA",null,{"v":0.072767,"d":"0.07"},0,"inf","inf",1,1,"up","no"]
["ENSG00000086967","MYBPC2","ENST00000357701","GO:0007155(cell adhesion);GO:0003779(actin binding);GO:0005515(protein binding);GO:0006936(muscle contraction);GO:0005829(cytosol);GO:0051015(actin filament binding);GO:0051371(muscle alpha-actinin binding);GO:0097493(structural molecule activity conferring elasticity);GO:0006941(striated muscle contraction);GO:0007015(actin filament organization);GO:0045214(sarcomere organization);GO:0071688(striated muscle myosin thick filament assembly);GO:0005859(muscle myosin complex);GO:0030018(Z disc);GO:0031430(M band);GO:0032982(myosin filament);GO:0008307(structural constituent of muscle);GO:0030049(muscle filament sliding)","NA","NA","NA","myosin binding protein C, fast type [Source:HGNC Symbol;Acc:HGNC:7550]",{"v":0.0429774350053937,"d":"0.04"},{"v":0.0137247173678533,"d":"0.01"},{"v":3.13138943801186,"d":"3.13"},{"v":1.64680294167687,"d":"1.65"},1,1,"up","no"]
["ENSG00000130649","CYP2E1","ENST00000463117;ENST00000469258;ENST00000421586;ENST00000418356;ENST00000368520","GO:0016020(membrane);GO:0046872(metal ion binding);GO:0004497(monooxygenase activity);GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005506(iron ion binding);GO:0016705(oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen);GO:0020037(heme binding);GO:0016712(oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen);GO:0008392(arachidonic acid epoxygenase activity);GO:0008395(steroid hydroxylase activity);GO:0019373(epoxygenase P450 pathway);GO:0043231(intracellular membrane-bounded organelle);GO:0006805(xenobiotic metabolic process);GO:0016709(oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen);GO:0031090(organelle membrane);GO:0019899(enzyme binding);GO:0019825(oxygen binding);GO:0008202(steroid metabolic process);GO:0017144(drug metabolic process);GO:0016098(monoterpenoid metabolic process);GO:0046483(heterocycle metabolic process);GO:0006641(triglyceride metabolic process);GO:0010193(response to ozone);GO:0010243(response to organonitrogen compound);GO:0018885(carbon tetrachloride metabolic process);GO:0018910(benzene metabolic process);GO:0042197(halogenated hydrocarbon metabolic process);GO:0042493(response to drug);GO:0045471(response to ethanol);GO:0000139(Golgi membrane);GO:0005739(mitochondrion);GO:0031227(intrinsic component of endoplasmic reticulum membrane);GO:0031227(intrinsic component of endoplasmic reticulum membrane)","00140(Steroid hormone biosynthesis);00590(Arachidonic acid metabolism);00591(Linoleic acid metabolism);00980(Metabolism of xenobiotics by cytochrome P450);00982(Drug metabolism - cytochrome P450);00983(Drug metabolism - other enzymes);05204(Chemical carcinogenesis);04932(Non-alcoholic fatty liver disease (NAFLD));04932(Non-alcoholic fatty liver disease (NAFLD))","NA","NA","cytochrome P450 family 2 subfamily E member 1 [Source:HGNC Symbol;Acc:HGNC:2631]",{"v":0.0720413312545473,"d":"0.07"},{"v":0.0668981945743686,"d":"0.07"},{"v":1.07688005203879,"d":"1.08"},{"v":0.106857564677005,"d":"0.11"},1,1,"up","no"]
["ENSG00000227521","AL390840.1","ENST00000420303","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["MSTRG.12252","EPB41L4A-AS2","ENST00000624967;ENST00000623705","NA","NA","NA","NA","EPB41L4A antisense RNA 2 (head to head) [Source:HGNC Symbol;Acc:HGNC:25643]",0,0,1,0,1,1,"no","no"]
["MSTRG.2264","FAR1-IT1","ENST00000525233","NA","NA","NA","NA","FAR1 intronic transcript 1 [Source:HGNC Symbol;Acc:HGNC:41485]",{"v":0.262498,"d":"0.26"},0,"inf","inf",1,1,"up","no"]
["ENSG00000126545","CSN1S1","ENST00000246891","GO:0006810(transport);GO:0005215(transporter activity);GO:0005576(extracellular region);GO:0055085(transmembrane transport)","NA","NA","NA","casein alpha s1 [Source:HGNC Symbol;Acc:HGNC:2445]",0,0,1,0,1,1,"no","no"]
["ENSG00000280135","AL096816.1","ENST00000623300","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000250329","KDELC1P1","ENST00000512118","NA","NA","NA","NA","KDEL motif containing 1 pseudogene 1 [Source:HGNC Symbol;Acc:HGNC:39193]",0,0,1,0,1,1,"no","no"]
["ENSG00000153012","LGI2","ENST00000382114","GO:0005576(extracellular region);GO:0005615(extracellular space)","NA","NA","NA","leucine rich repeat LGI family member 2 [Source:HGNC Symbol;Acc:HGNC:18710]",{"v":0.049583,"d":"0.05"},{"v":0.023625,"d":"0.02"},{"v":2.09875132275132,"d":"2.10"},{"v":1.06953123443029,"d":"1.07"},1,1,"up","no"]
["ENSG00000161860","SYCE2","ENST00000293695;ENST00000591229","GO:0005634(nucleus);GO:0051301(cell division);GO:0007130(synaptonemal complex assembly);GO:0007049(cell cycle);GO:0051321(meiotic cell cycle);GO:0000801(central element);GO:0000801(central element)","NA","NA","NA","synaptonemal complex central element protein 2 [Source:HGNC Symbol;Acc:HGNC:27411]",{"v":0.154959595336077,"d":"0.15"},{"v":0.00427641632373114,"d":"0.00"},{"v":36.2358534823092,"d":"36.24"},{"v":5.17934597017301,"d":"5.18"},1,1,"up","no"]
["ENSG00000230268","SSU72P8","ENST00000473520","GO:0005634(nucleus);GO:0004721(phosphoprotein phosphatase activity);GO:0006397(mRNA processing);GO:0006470(protein dephosphorylation)","NA","NA","NA","SSU72 pseudogene 8 [Source:HGNC Symbol;Acc:HGNC:43627]",0,0,1,0,1,1,"no","no"]
["ENSG00000280693","SH3PXD2A-AS1","ENST00000627886","NA","NA","NA","NA","SH3PXD2A antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:45242]",{"v":0.0239601091565178,"d":"0.02"},{"v":0.0309727794316644,"d":"0.03"},{"v":0.773586019600897,"d":"0.77"},{"v":-0.370366372506304,"d":"-0.37"},1,1,"down","no"]
["ENSG00000167720","SRR","ENST00000572709;ENST00000575840;ENST00000570662;ENST00000344595;ENST00000574229","GO:0030170(pyridoxal phosphate binding);GO:0006520(cellular amino acid metabolic process);GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0016853(isomerase activity);GO:0016829(lyase activity);GO:0042803(protein homodimerization activity);GO:0003824(catalytic activity);GO:0008152(metabolic process);GO:0000287(magnesium ion binding);GO:0005509(calcium ion binding);GO:0032496(response to lipopolysaccharide);GO:0051289(protein homotetramerization);GO:0030165(PDZ domain binding);GO:0043025(neuronal cell body);GO:0016594(glycine binding);GO:0070178(D-serine metabolic process);GO:0003941(L-serine ammonia-lyase activity);GO:0042866(pyruvate biosynthetic process);GO:0006563(L-serine metabolic process);GO:0008721(D-serine ammonia-lyase activity);GO:0018114(threonine racemase activity);GO:0030378(serine racemase activity);GO:0007420(brain development);GO:0007568(aging);GO:0009069(serine family amino acid metabolic process);GO:0014070(response to organic cyclic compound);GO:0042493(response to drug);GO:0043278(response to morphine);GO:0070179(D-serine biosynthetic process);GO:0005886(plasma membrane);GO:0045177(apical part of cell);GO:0045177(apical part of cell)","00260(Glycine, serine and threonine metabolism);00260(Glycine, serine and threonine metabolism)","K12235","EC:5.1.1.18","serine racemase [Source:HGNC Symbol;Acc:HGNC:14398]",{"v":0.203599913664951,"d":"0.20"},{"v":0.54159196112064,"d":"0.54"},{"v":0.375928610985419,"d":"0.38"},{"v":-1.41146937542025,"d":"-1.41"},1,1,"down","no"]
["ENSG00000265158","LRRC37A7P","ENST00000583900","NA","NA","NA","NA","leucine rich repeat containing 37 member A7, pseudogene [Source:HGNC Symbol;Acc:HGNC:43792]",{"v":0.014344,"d":"0.01"},0,"inf","inf",1,1,"up","no"]
["ENSG00000262115","AC027601.2","ENST00000571085","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000226498","RPSAP21","ENST00000414293","NA","NA","NA","NA","ribosomal protein SA pseudogene 21 [Source:HGNC Symbol;Acc:HGNC:36928]",0,0,1,0,1,1,"no","no"]
["MSTRG.402","RN7SKP16","ENST00000410180","NA","NA","NA","NA","RNA, 7SK small nuclear pseudogene 16 [Source:HGNC Symbol;Acc:HGNC:45740]",0,{"v":0.164571,"d":"0.16"},"-inf","-inf",1,1,"down","no"]
["MSTRG.8804","ATP6V1B1","ENST00000432367","GO:0006810(transport);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005524(ATP binding);GO:0016787(hydrolase activity);GO:0015992(proton transport);GO:0006811(ion transport);GO:0015991(ATP hydrolysis coupled proton transport);GO:0016820(hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances);GO:0033180(proton-transporting V-type ATPase, V1 domain);GO:0046034(ATP metabolic process);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0034220(ion transmembrane transport);GO:0016323(basolateral plasma membrane);GO:0012505(endomembrane system);GO:0007605(sensory perception of sound);GO:0005902(microvillus);GO:0016328(lateral plasma membrane);GO:0016324(apical plasma membrane);GO:0008286(insulin receptor signaling pathway);GO:0016241(regulation of macroautophagy);GO:0033572(transferrin transport);GO:0090383(phagosome acidification);GO:0007588(excretion);GO:0042472(inner ear morphogenesis);GO:0055074(calcium ion homeostasis);GO:0015078(hydrogen ion transmembrane transporter activity);GO:0032403(protein complex binding);GO:0001503(ossification);GO:0006885(regulation of pH);GO:0045851(pH reduction);GO:0008021(synaptic vesicle);GO:0016471(vacuolar proton-transporting V-type ATPase complex);GO:0098850(extrinsic component of synaptic vesicle membrane)","00190(Oxidative phosphorylation);04150(mTOR signaling pathway);04145(Phagosome);04966(Collecting duct acid secretion);04721(Synaptic vesicle cycle);05323(Rheumatoid arthritis);05110(Vibrio cholerae infection);05120(Epithelial cell signaling in Helicobacter pylori infection)","NA","NA","ATPase H+ transporting V1 subunit B1 [Source:HGNC Symbol;Acc:HGNC:853]",0,0,1,0,1,1,"no","no"]
["ENSG00000184385","UMODL1-AS1","ENST00000329015","NA","NA","NA","NA","UMODL1 antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:23821]",{"v":0.114576,"d":"0.11"},{"v":0.186341,"d":"0.19"},{"v":0.614872733322243,"d":"0.61"},{"v":-0.701640263305561,"d":"-0.70"},1,1,"down","no"]
["MSTRG.6020","AGRP","ENST00000290953","GO:0005794(Golgi apparatus);GO:0005102(receptor binding);GO:0005576(extracellular region);GO:0005615(extracellular space);GO:0007218(neuropeptide signaling pathway);GO:0070062(extracellular exosome);GO:0005184(neuropeptide hormone activity);GO:0007623(circadian rhythm);GO:0008343(adult feeding behavior);GO:0009755(hormone-mediated signaling pathway);GO:0032868(response to insulin);GO:0042755(eating behavior);GO:0048571(long-day photoperiodism);GO:0060135(maternal process involved in female pregnancy);GO:2000253(positive regulation of feeding behavior);GO:0043025(neuronal cell body);GO:0007631(feeding behavior);GO:0060259(regulation of feeding behavior);GO:0005796(Golgi lumen)","04920(Adipocytokine signaling pathway)","K05231","NA","agouti related neuropeptide [Source:HGNC Symbol;Acc:HGNC:330]",{"v":0.236003,"d":"0.24"},{"v":0.347873,"d":"0.35"},{"v":0.678417123490469,"d":"0.68"},{"v":-0.559755510388651,"d":"-0.56"},1,1,"down","no"]
["ENSG00000278694","AL354980.1","ENST00000612670","NA","NA","NA","NA",null,0,{"v":0.107663,"d":"0.11"},"-inf","-inf",1,1,"down","no"]
["MSTRG.3230","C12orf60","ENST00000527783;ENST00000330828","NA","NA","NA","NA","chromosome 12 open reading frame 60 [Source:HGNC Symbol;Acc:HGNC:28726]",{"v":0.139213366739606,"d":"0.14"},{"v":0.127658991684902,"d":"0.13"},{"v":1.09050968445077,"d":"1.09"},{"v":0.125002582126358,"d":"0.13"},1,1,"up","no"]
["ENSG00000279642","AL023973.1","ENST00000624619","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["MSTRG.15261","UXT-AS1","ENST00000590504;ENST00000591832","NA","NA","NA","NA","UXT antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:49239]",0,0,1,0,1,1,"no","no"]
["ENSG00000225493","LINC01107","ENST00000446979","NA","NA","NA","NA","long intergenic non-protein coding RNA 1107 [Source:HGNC Symbol;Acc:HGNC:49229]",{"v":0.026896,"d":"0.03"},0,"inf","inf",1,1,"up","no"]
["ENSG00000143248","RGS5","ENST00000530241;ENST00000367903;ENST00000313961","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005829(cytosol);GO:0043547(positive regulation of GTPase activity);GO:0005886(plasma membrane);GO:0009968(negative regulation of signal transduction);GO:0005096(GTPase activator activity);GO:0008277(regulation of G-protein coupled receptor protein signaling pathway);GO:0008277(regulation of G-protein coupled receptor protein signaling pathway)","NA","NA","NA","regulator of G protein signaling 5 [Source:HGNC Symbol;Acc:HGNC:10001]",{"v":0.0530441817915262,"d":"0.05"},{"v":0.0391156299662806,"d":"0.04"},{"v":1.35608660367359,"d":"1.36"},{"v":0.439449316159151,"d":"0.44"},1,1,"up","no"]
["ENSG00000075073","TACR2","ENST00000373307;ENST00000373306","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0004930(G-protein coupled receptor activity);GO:0007186(G-protein coupled receptor signaling pathway);GO:0005886(plasma membrane);GO:0004995(tachykinin receptor activity);GO:0007217(tachykinin receptor signaling pathway);GO:0005515(protein binding);GO:0004871(signal transducer activity);GO:0007165(signal transduction);GO:0005887(integral component of plasma membrane);GO:0006936(muscle contraction);GO:0007268(chemical synaptic transmission);GO:0007588(excretion);GO:0016497(substance K receptor activity);GO:0014057(positive regulation of acetylcholine secretion, neurotransmission);GO:0014827(intestine smooth muscle contraction);GO:0033685(negative regulation of luteinizing hormone secretion);GO:0035106(operant conditioning);GO:0043117(positive regulation of vascular permeability);GO:0043270(positive regulation of ion transport);GO:0045987(positive regulation of smooth muscle contraction);GO:0051602(response to electrical stimulus);GO:0070459(prolactin secretion);GO:0070472(regulation of uterine smooth muscle contraction);GO:0070474(positive regulation of uterine smooth muscle contraction);GO:0070474(positive regulation of uterine smooth muscle contraction)","04020(Calcium signaling pathway);04080(Neuroactive ligand-receptor interaction);04080(Neuroactive ligand-receptor interaction)","K04223","NA","tachykinin receptor 2 [Source:HGNC Symbol;Acc:HGNC:11527]",{"v":0.0209527272727273,"d":"0.02"},0,"inf","inf",1,1,"up","no"]
["ENSG00000227242","NBPF13P","ENST00000444082","NA","NA","NA","NA","NBPF member 13, pseudogene [Source:HGNC Symbol;Acc:HGNC:31995]",{"v":0.115627,"d":"0.12"},{"v":0.293648,"d":"0.29"},{"v":0.39376055685719,"d":"0.39"},{"v":-1.34460949171418,"d":"-1.34"},1,1,"down","no"]
["ENSG00000269560","AC010422.4","ENST00000601420","NA","NA","NA","NA",null,0,{"v":0.045113,"d":"0.05"},"-inf","-inf",1,1,"down","no"]
["ENSG00000221986","MYBPHL","ENST00000357155","GO:0003674(molecular_function);GO:0008150(biological_process);GO:0005575(cellular_component);GO:0005515(protein binding);GO:0008307(structural constituent of muscle);GO:0051015(actin filament binding);GO:0051371(muscle alpha-actinin binding);GO:0097493(structural molecule activity conferring elasticity);GO:0006941(striated muscle contraction);GO:0007015(actin filament organization);GO:0045214(sarcomere organization);GO:0071688(striated muscle myosin thick filament assembly);GO:0005859(muscle myosin complex);GO:0030018(Z disc);GO:0031430(M band)","NA","NA","NA","myosin binding protein H like [Source:HGNC Symbol;Acc:HGNC:30434]",0,0,1,0,1,1,"no","no"]
["ENSG00000134201","GSTM5","ENST00000369813","GO:0005737(cytoplasm);GO:0016740(transferase activity);GO:0008152(metabolic process);GO:0005515(protein binding);GO:0004364(glutathione transferase activity);GO:0042802(identical protein binding);GO:0005829(cytosol);GO:1901687(glutathione derivative biosynthetic process);GO:0006749(glutathione metabolic process)","00480(Glutathione metabolism);00980(Metabolism of xenobiotics by cytochrome P450);00982(Drug metabolism - cytochrome P450);00983(Drug metabolism - other enzymes);05200(Pathways in cancer);05204(Chemical carcinogenesis);05225(Hepatocellular carcinoma);05418(Fluid shear stress and atherosclerosis);01524(Platinum drug resistance)","NA","NA","glutathione S-transferase mu 5 [Source:HGNC Symbol;Acc:HGNC:4637]",0,0,1,0,1,1,"no","no"]
["ENSG00000165409","TSHR","ENST00000342443;ENST00000557096;ENST00000541158;ENST00000553763","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0004930(G-protein coupled receptor activity);GO:0007186(G-protein coupled receptor signaling pathway);GO:0005886(plasma membrane);GO:0004871(signal transducer activity);GO:0007165(signal transduction);GO:0004996(thyroid-stimulating hormone receptor activity);GO:0016500(protein-hormone receptor activity);GO:0007189(adenylate cyclase-activating G-protein coupled receptor signaling pathway);GO:0008344(adult locomotory behavior);GO:0030183(B cell differentiation);GO:0038194(thyroid-stimulating hormone signaling pathway);GO:0040012(regulation of locomotion);GO:0040018(positive regulation of multicellular organism growth);GO:0060119(inner ear receptor cell development);GO:0060122(inner ear receptor stereocilium organization);GO:0071542(dopaminergic neuron differentiation);GO:0090103(cochlea morphogenesis);GO:0005515(protein binding);GO:0007399(nervous system development);GO:0016323(basolateral plasma membrane);GO:0004872(receptor activity);GO:0009755(hormone-mediated signaling pathway);GO:0005887(integral component of plasma membrane);GO:0007267(cell-cell signaling);GO:0009986(cell surface);GO:0032403(protein complex binding);GO:0043235(receptor complex);GO:0008284(positive regulation of cell proliferation);GO:0030819(positive regulation of cAMP biosynthetic process);GO:0007166(cell surface receptor signaling pathway);GO:0045762(positive regulation of adenylate cyclase activity);GO:0007187(G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger);GO:0008528(G-protein coupled peptide receptor activity);GO:0007190(activation of adenylate cyclase activity);GO:1904588(cellular response to glycoprotein);GO:1905229(cellular response to thyrotropin-releasing hormone);GO:1905229(cellular response to thyrotropin-releasing hormone)","04024(cAMP signaling pathway);04080(Neuroactive ligand-receptor interaction);04923(Regulation of lipolysis in adipocyte);04918(Thyroid hormone synthesis);05320(Autoimmune thyroid disease);05320(Autoimmune thyroid disease)","K04249","NA","thyroid stimulating hormone receptor [Source:HGNC Symbol;Acc:HGNC:12373]",0,{"v":0.0337591324296142,"d":"0.03"},"-inf","-inf",1,1,"down","no"]
["ENSG00000187905","LRRC74B","ENST00000497328","NA","NA","NA","NA","leucine rich repeat containing 74B [Source:HGNC Symbol;Acc:HGNC:34301]",0,0,1,0,1,1,"no","no"]
["MSTRG.8163","CYP2F2P","ENST00000437853;ENST00000641827","NA","NA","NA","NA","cytochrome P450 family 2 subfamily F member 2, pseudogene [Source:HGNC Symbol;Acc:HGNC:18851]",{"v":0.25500865416936,"d":"0.26"},{"v":0.0118562792501616,"d":"0.01"},{"v":21.5083205100693,"d":"21.51"},{"v":4.4268229703507,"d":"4.43"},1,1,"up","no"]
["ENSG00000277152","AC110048.2","ENST00000617013","NA","NA","NA","NA",null,{"v":0.02358,"d":"0.02"},0,"inf","inf",1,1,"up","no"]
["ENSG00000165181","C9orf84","ENST00000394779;ENST00000374283","NA","NA","NA","NA","chromosome 9 open reading frame 84 [Source:HGNC Symbol;Acc:HGNC:26535]",{"v":0.0457721988527725,"d":"0.05"},{"v":0.0531455623008285,"d":"0.05"},{"v":0.861260975915179,"d":"0.86"},{"v":-0.215477631238796,"d":"-0.22"},1,1,"down","no"]
["ENSG00000166787","SAA3P","ENST00000533267","NA","NA","NA","NA","serum amyloid A3 pseudogene [Source:HGNC Symbol;Acc:HGNC:10515]",0,0,1,0,1,1,"no","no"]
["ENSG00000235574","AC073150.1","ENST00000450406","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000251191","LINC00589","ENST00000518623","NA","NA","NA","NA","long intergenic non-protein coding RNA 589 [Source:HGNC Symbol;Acc:HGNC:32299]",{"v":0.0254426846673095,"d":"0.03"},0,"inf","inf",1,1,"up","no"]
["ENSG00000225210","DUXAP9","ENST00000620237;ENST00000621361;ENST00000622815;ENST00000619210","NA","NA","NA","NA","double homeobox A pseudogene 9 [Source:HGNC Symbol;Acc:HGNC:32188]",0,{"v":0.00583310315252666,"d":"0.01"},"-inf","-inf",1,1,"down","no"]
["MSTRG.9194","AC009299.3","ENST00000421122;ENST00000435692","NA","NA","NA","NA",null,{"v":0.0514658477690289,"d":"0.05"},{"v":0.00822,"d":"0.01"},{"v":6.26105204002785,"d":"6.26"},{"v":2.6464050925267,"d":"2.65"},1,1,"up","no"]
["ENSG00000108821","COL1A1","ENST00000225964;ENST00000510710","GO:0005615(extracellular space);GO:0046872(metal ion binding);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0005581(collagen trimer);GO:0005578(proteinaceous extracellular matrix);GO:0005201(extracellular matrix structural constituent);GO:0045893(positive regulation of transcription, DNA-templated);GO:0050776(regulation of immune response);GO:0050900(leukocyte migration);GO:0031012(extracellular matrix);GO:0001501(skeletal system development);GO:0030335(positive regulation of cell migration);GO:0007601(visual perception);GO:0042802(identical protein binding);GO:0030574(collagen catabolic process);GO:0007605(sensory perception of sound);GO:0090263(positive regulation of canonical Wnt signaling pathway);GO:0030168(platelet activation);GO:0005788(endoplasmic reticulum lumen);GO:0030198(extracellular matrix organization);GO:0010718(positive regulation of epithelial to mesenchymal transition);GO:0034504(protein localization to nucleus);GO:0030199(collagen fibril organization);GO:0007596(blood coagulation);GO:0001568(blood vessel development);GO:0048706(embryonic skeletal system development);GO:0002020(protease binding);GO:0048407(platelet-derived growth factor binding);GO:0001503(ossification);GO:0001649(osteoblast differentiation);GO:0001957(intramembranous ossification);GO:0001958(endochondral ossification);GO:0007584(response to nutrient);GO:0009612(response to mechanical stimulus);GO:0010812(negative regulation of cell-substrate adhesion);GO:0015031(protein transport);GO:0031667(response to nutrient levels);GO:0031960(response to corticosteroid);GO:0032355(response to estradiol);GO:0032964(collagen biosynthetic process);GO:0034505(tooth mineralization);GO:0038063(collagen-activated tyrosine kinase receptor signaling pathway);GO:0042060(wound healing);GO:0042493(response to drug);GO:0042542(response to hydrogen peroxide);GO:0043434(response to peptide hormone);GO:0043588(skin development);GO:0043589(skin morphogenesis);GO:0044344(cellular response to fibroblast growth factor stimulus);GO:0044691(tooth eruption);GO:0048545(response to steroid hormone);GO:0048705(skeletal system morphogenesis);GO:0051591(response to cAMP);GO:0055093(response to hyperoxia);GO:0060325(face morphogenesis);GO:0060346(bone trabecula formation);GO:0060351(cartilage development involved in endochondral bone morphogenesis);GO:0070208(protein heterotrimerization);GO:0071230(cellular response to amino acid stimulus);GO:0071260(cellular response to mechanical stimulus);GO:0071300(cellular response to retinoic acid);GO:0071306(cellular response to vitamin E);GO:0071356(cellular response to tumor necrosis factor);GO:0071364(cellular response to epidermal growth factor stimulus);GO:0071560(cellular response to transforming growth factor beta stimulus);GO:1902617(response to fluoride);GO:1902618(cellular response to fluoride);GO:0005584(collagen type I trimer);GO:0005737(cytoplasm);GO:0005783(endoplasmic reticulum);GO:0005794(Golgi apparatus);GO:0030141(secretory granule);GO:0030141(secretory granule)","04151(PI3K-Akt signaling pathway);04512(ECM-receptor interaction);04510(Focal adhesion);04611(Platelet activation);04926(Relaxin signaling pathway);04974(Protein digestion and absorption);04933(AGE-RAGE signaling pathway in diabetic complications);05165(Human papillomavirus infection);05146(Amoebiasis);05146(Amoebiasis)","K06236","NA","collagen type I alpha 1 chain [Source:HGNC Symbol;Acc:HGNC:2197]",0,{"v":1.38116223648029E-3,"d":"0.00"},"-inf","-inf",1,1,"down","no"]
["MSTRG.1140","CFAP126","ENST00000367974","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005886(plasma membrane);GO:0005856(cytoskeleton);GO:0042995(cell projection);GO:0005929(cilium);GO:0030030(cell projection organization);GO:0036064(ciliary basal body);GO:0016324(apical plasma membrane);GO:0044782(cilium organization)","NA","NA","NA","cilia and flagella associated protein 126 [Source:HGNC Symbol;Acc:HGNC:32325]",0,0,1,0,1,1,"no","no"]
["ENSG00000236831","YME1L1P1","ENST00000429435","NA","NA","NA","NA","YME1L1 pseudogene 1 [Source:HGNC Symbol;Acc:HGNC:12844]",0,0,1,0,1,1,"no","no"]
["ENSG00000116675","DNAJC6","ENST00000494710;ENST00000371069;ENST00000463018;ENST00000263441","GO:0016787(hydrolase activity);GO:0035335(peptidyl-tyrosine dephosphorylation);GO:0004721(phosphoprotein phosphatase activity);GO:0006470(protein dephosphorylation);GO:0004725(protein tyrosine phosphatase activity);GO:0005829(cytosol);GO:0061024(membrane organization);GO:0017124(SH3 domain binding);GO:0016191(synaptic vesicle uncoating);GO:0006898(receptor-mediated endocytosis);GO:0031982(vesicle);GO:0072318(clathrin coat disassembly);GO:2000369(regulation of clathrin-dependent endocytosis);GO:0014069(postsynaptic density);GO:0045202(synapse);GO:0045202(synapse)","04144(Endocytosis);04144(Endocytosis)","K09526","NA","DnaJ heat shock protein family (Hsp40) member C6 [Source:HGNC Symbol;Acc:HGNC:15469]",{"v":0.140098563416739,"d":"0.14"},{"v":0.0872140386827725,"d":"0.09"},{"v":1.60637628451454,"d":"1.61"},{"v":0.683809875555562,"d":"0.68"},1,1,"up","no"]
["MSTRG.544","AL162430.2","ENST00000422306","NA","NA","NA","NA",null,{"v":0.021431,"d":"0.02"},{"v":0.037964,"d":"0.04"},{"v":0.564508481719524,"d":"0.56"},{"v":-0.824932837285423,"d":"-0.82"},1,1,"down","no"]
["ENSG00000046774","MAGEC2","ENST00000247452","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005730(nucleolus);GO:0005829(cytosol);GO:0005515(protein binding);GO:0044257(cellular protein catabolic process);GO:0031625(ubiquitin protein ligase binding);GO:0051443(positive regulation of ubiquitin-protein transferase activity)","NA","NA","NA","MAGE family member C2 [Source:HGNC Symbol;Acc:HGNC:13574]",0,0,1,0,1,1,"no","no"]
["ENSG00000228121","PHBP3","ENST00000412562","NA","NA","NA","NA","prohibitin pseudogene 3 [Source:HGNC Symbol;Acc:HGNC:8915]",0,0,1,0,1,1,"no","no"]
["ENSG00000163239","TDRD10","ENST00000368482","GO:0003676(nucleic acid binding);GO:0003723(RNA binding)","NA","NA","NA","tudor domain containing 10 [Source:HGNC Symbol;Acc:HGNC:25316]",0,{"v":0.0188073625277162,"d":"0.02"},"-inf","-inf",1,1,"down","no"]
["ENSG00000152439","ZNF773","ENST00000597061;ENST00000593916;ENST00000598770;ENST00000599847;ENST00000282292;ENST00000601958","GO:0003676(nucleic acid binding);GO:0006355(regulation of transcription, DNA-templated);GO:0005622(intracellular);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0003677(DNA binding)","NA","NA","NA","zinc finger protein 773 [Source:HGNC Symbol;Acc:HGNC:30487]",{"v":0.394209936826459,"d":"0.39"},{"v":0.0385842054998142,"d":"0.04"},{"v":10.2168732443735,"d":"10.22"},{"v":3.35288183861605,"d":"3.35"},1,1,"up","no"]
["ENSG00000280594","BTG3-AS1","ENST00000630155","NA","NA","NA","NA","BTG3 antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:53145]",{"v":0.0616106159813809,"d":"0.06"},0,"inf","inf",1,1,"up","no"]
["MSTRG.10733","THRB","ENST00000396671","GO:0005634(nucleus);GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0043565(sequence-specific DNA binding);GO:0003707(steroid hormone receptor activity);GO:0030522(intracellular receptor signaling pathway);GO:0043401(steroid hormone mediated signaling pathway);GO:0016604(nuclear body);GO:0005515(protein binding);GO:0005654(nucleoplasm);GO:0070062(extracellular exosome);GO:0004887(thyroid hormone receptor activity);GO:0019899(enzyme binding);GO:0003714(transcription corepressor activity);GO:0006367(transcription initiation from RNA polymerase II promoter);GO:0070324(thyroid hormone binding);GO:0007165(signal transduction);GO:0031490(chromatin DNA binding);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0007605(sensory perception of sound);GO:0007621(negative regulation of female receptivity);GO:0008016(regulation of heart contraction);GO:0008050(female courtship behavior);GO:0009887(animal organ morphogenesis);GO:0045892(negative regulation of transcription, DNA-templated);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0060509(Type I pneumocyte differentiation);GO:0000790(nuclear chromatin)","04080(Neuroactive ligand-receptor interaction);04919(Thyroid hormone signaling pathway)","K08362","NA","thyroid hormone receptor beta [Source:HGNC Symbol;Acc:HGNC:11799]",{"v":0.111252382363073,"d":"0.11"},{"v":0.0496676734412677,"d":"0.05"},{"v":2.23993544804609,"d":"2.24"},{"v":1.16345715633391,"d":"1.16"},1,1,"up","no"]
["ENSG00000131386","GALNT15","ENST00000489467;ENST00000339732","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0046872(metal ion binding);GO:0016740(transferase activity);GO:0030246(carbohydrate binding);GO:0016757(transferase activity, transferring glycosyl groups);GO:0005794(Golgi apparatus);GO:0000139(Golgi membrane);GO:0006486(protein glycosylation);GO:0016266(O-glycan processing);GO:0030133(transport vesicle);GO:0004653(polypeptide N-acetylgalactosaminyltransferase activity);GO:0004653(polypeptide N-acetylgalactosaminyltransferase activity)","00512(Mucin type O-glycan biosynthesis);00512(Mucin type O-glycan biosynthesis)","K00710","EC:2.4.1.41","polypeptide N-acetylgalactosaminyltransferase 15 [Source:HGNC Symbol;Acc:HGNC:21531]",{"v":0.00380967282972354,"d":"0.00"},{"v":0.00896145448142279,"d":"0.01"},{"v":0.425117690171952,"d":"0.43"},{"v":-1.23406580064249,"d":"-1.23"},1,1,"down","no"]
["ENSG00000245573","BDNF-AS","ENST00000499008;ENST00000499568;ENST00000501663","NA","NA","NA","NA","BDNF antisense RNA [Source:HGNC Symbol;Acc:HGNC:20608]",{"v":0.0709992603327966,"d":"0.07"},{"v":0.054453078904992,"d":"0.05"},{"v":1.30386126479044,"d":"1.30"},{"v":0.38279037014652,"d":"0.38"},1,1,"up","no"]
["MSTRG.11560","AC104078.2","MSTRG.11560.1","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["MSTRG.4941","PWAR1","ENST00000624188","NA","NA","NA","NA","Prader Willi/Angelman region RNA 1 [Source:HGNC Symbol;Acc:HGNC:30089]",{"v":0.04299,"d":"0.04"},0,"inf","inf",1,1,"up","no"]
["MSTRG.2606","AP003419.4","ENST00000616071","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000188909","BSX","ENST00000343035","GO:0005634(nucleus);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0043565(sequence-specific DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0007626(locomotory behavior);GO:0042755(eating behavior);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0060056(mammary gland involution);GO:0005667(transcription factor complex);GO:0005737(cytoplasm)","NA","NA","NA","brain specific homeobox [Source:HGNC Symbol;Acc:HGNC:20450]",0,0,1,0,1,1,"no","no"]
["ENSG00000241566","IGKV2D-24","ENST00000462693","GO:0002377(immunoglobulin production);GO:0006955(immune response);GO:0005615(extracellular space)","NA","NA","NA","immunoglobulin kappa variable 2D-24 (non-functional) [Source:HGNC Symbol;Acc:HGNC:5797]",{"v":0.651707,"d":"0.65"},{"v":0.43987,"d":"0.44"},{"v":1.48159001523177,"d":"1.48"},{"v":0.567146281097299,"d":"0.57"},1,1,"up","no"]
["ENSG00000249661","TNRC18P1","ENST00000502875","NA","NA","NA","NA","trinucleotide repeat containing 18 pseudogene 1 [Source:HGNC Symbol;Acc:HGNC:43881]",{"v":0.072381,"d":"0.07"},{"v":0.013943,"d":"0.01"},{"v":5.19120705730474,"d":"5.19"},{"v":2.37607003243967,"d":"2.38"},1,1,"up","no"]
["ENSG00000160321","ZNF208","ENST00000609966;ENST00000397126","GO:0003676(nucleic acid binding);GO:0006355(regulation of transcription, DNA-templated);GO:0005622(intracellular);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0008270(zinc ion binding);GO:0008270(zinc ion binding)","NA","NA","NA","zinc finger protein 208 [Source:HGNC Symbol;Acc:HGNC:12999]",{"v":0.116084049949032,"d":"0.12"},{"v":0.0369325399737877,"d":"0.04"},{"v":3.14313746174568,"d":"3.14"},{"v":1.65220536823663,"d":"1.65"},1,1,"up","no"]
["ENSG00000275954","TBC1D3F","ENST00000620210","NA","NA","NA","NA","TBC1 domain family member 3F [Source:HGNC Symbol;Acc:HGNC:18257]",{"v":0.379839,"d":"0.38"},{"v":0.30461,"d":"0.30"},{"v":1.24696825448935,"d":"1.25"},{"v":0.318424737281645,"d":"0.32"},1,1,"up","no"]
["MSTRG.8325","MIR5088","ENST00000615402","NA","NA","NA","NA","microRNA 5088 [Source:HGNC Symbol;Acc:HGNC:43489]",0,{"v":0.004266,"d":"0.00"},"-inf","-inf",1,1,"down","no"]
["MSTRG.15036","MIR6855","ENST00000622178","NA","NA","NA","NA","microRNA 6855 [Source:HGNC Symbol;Acc:HGNC:50061]",0,0,1,0,1,1,"no","no"]
["ENSG00000256849","TCP1P3","ENST00000414406","NA","NA","NA","NA","t-complex 1 pseudogene 3 [Source:HGNC Symbol;Acc:HGNC:21630]",0,0,1,0,1,1,"no","no"]
["ENSG00000258476","LINC02207","ENST00000556030;ENST00000554530","NA","NA","NA","NA","long intergenic non-protein coding RNA 2207 [Source:HGNC Symbol;Acc:HGNC:53073]",{"v":0.342307147582697,"d":"0.34"},{"v":0.182072491094148,"d":"0.18"},{"v":1.88005967033039,"d":"1.88"},{"v":0.910778451649512,"d":"0.91"},1,1,"up","no"]
["ENSG00000255442","AC109635.5","ENST00000533593","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000267253","AC055813.1","ENST00000587110","NA","NA","NA","NA",null,0,{"v":0.023972,"d":"0.02"},"-inf","-inf",1,1,"down","no"]
["ENSG00000262904","TMPOP2","ENST00000575258","NA","NA","NA","NA","thymopoietin pseudogene 2 [Source:HGNC Symbol;Acc:HGNC:50860]",{"v":0.04423,"d":"0.04"},0,"inf","inf",1,1,"up","no"]
["ENSG00000254040","AC103719.1","ENST00000517994","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000197479","PCDHB11","ENST00000354757","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005509(calcium ion binding);GO:0007155(cell adhesion);GO:0007156(homophilic cell adhesion via plasma membrane adhesion molecules);GO:0005886(plasma membrane);GO:0005887(integral component of plasma membrane);GO:0007268(chemical synaptic transmission);GO:0007399(nervous system development);GO:0007416(synapse assembly);GO:0016339(calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules)","NA","NA","NA","protocadherin beta 11 [Source:HGNC Symbol;Acc:HGNC:8682]",0,0,1,0,1,1,"no","no"]
["ENSG00000124575","HIST1H1D","ENST00000244534","GO:0005634(nucleus);GO:0003723(RNA binding);GO:0003677(DNA binding);GO:0031490(chromatin DNA binding);GO:0006334(nucleosome assembly);GO:0000786(nucleosome);GO:0000790(nuclear chromatin);GO:0005694(chromosome);GO:0005719(nuclear euchromatin);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0016584(nucleosome positioning);GO:0080182(histone H3-K4 trimethylation);GO:0098532(histone H3-K27 trimethylation)","NA","NA","NA","histone cluster 1 H1 family member d [Source:HGNC Symbol;Acc:HGNC:4717]",0,0,1,0,1,1,"no","no"]
["ENSG00000269911","FAM226B","ENST00000602508","NA","NA","NA","NA","family with sequence similarity 226 member B (non-protein coding) [Source:HGNC Symbol;Acc:HGNC:31964]",{"v":0.480933,"d":"0.48"},{"v":0.54615,"d":"0.55"},{"v":0.880587750617962,"d":"0.88"},{"v":-0.183461319026857,"d":"-0.18"},1,1,"down","no"]
["ENSG00000226995","LINC00658","ENST00000600157","NA","NA","NA","NA","long intergenic non-protein coding RNA 658 [Source:HGNC Symbol;Acc:HGNC:44315]",0,{"v":0.0197639161165049,"d":"0.02"},"-inf","-inf",1,1,"down","no"]
["ENSG00000260266","AC090826.1","ENST00000562009;ENST00000569235","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["MSTRG.13028","AL035588.1","ENST00000438967","NA","NA","NA","NA",null,{"v":0.138276,"d":"0.14"},0,"inf","inf",1,1,"up","no"]
["ENSG00000255455","AP003486.1","ENST00000525716","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000184486","POU3F2","ENST00000328345","GO:0005634(nucleus);GO:0006355(regulation of transcription, DNA-templated);GO:0006366(transcription from RNA polymerase II promoter);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0043565(sequence-specific DNA binding);GO:0005515(protein binding);GO:0007399(nervous system development);GO:0030154(cell differentiation);GO:0007420(brain development);GO:0042802(identical protein binding);GO:0048666(neuron development);GO:0048665(neuron fate specification);GO:0030182(neuron differentiation);GO:0008284(positive regulation of cell proliferation);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:0001077(transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0001105(RNA polymerase II transcription coactivator activity);GO:0008544(epidermis development);GO:0010629(negative regulation of gene expression);GO:0014002(astrocyte development);GO:0014044(Schwann cell development);GO:0021799(cerebral cortex radially oriented cell migration);GO:0021869(forebrain ventricular zone progenitor cell division);GO:0021979(hypothalamus cell differentiation);GO:0021985(neurohypophysis development);GO:0022011(myelination in peripheral nervous system);GO:0040018(positive regulation of multicellular organism growth);GO:0045595(regulation of cell differentiation);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0048663(neuron fate commitment);GO:0050770(regulation of axonogenesis);GO:0071310(cellular response to organic substance);GO:0005667(transcription factor complex)","NA","NA","NA","POU class 3 homeobox 2 [Source:HGNC Symbol;Acc:HGNC:9215]",0,0,1,0,1,1,"no","no"]
["ENSG00000244061","AC093278.1","ENST00000494700","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000241499","AL132838.2","ENST00000492041","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000178031","ADAMTSL1","ENST00000276935;ENST00000380548","GO:0008270(zinc ion binding);GO:0016787(hydrolase activity);GO:0005576(extracellular region);GO:0006508(proteolysis);GO:0005578(proteinaceous extracellular matrix);GO:0004222(metalloendopeptidase activity);GO:0008233(peptidase activity);GO:0005788(endoplasmic reticulum lumen);GO:0036066(protein O-linked fucosylation);GO:0036066(protein O-linked fucosylation)","NA","NA","NA","ADAMTS like 1 [Source:HGNC Symbol;Acc:HGNC:14632]",0,0,1,0,1,1,"no","no"]
["MSTRG.5782","AC109460.2","ENST00000568057","NA","NA","NA","NA",null,{"v":0.723751472527473,"d":"0.72"},{"v":0.217189038461538,"d":"0.22"},{"v":3.33235727573628,"d":"3.33"},{"v":1.73654308626791,"d":"1.74"},1,1,"up","no"]
["ENSG00000230325","AL359921.1","ENST00000433131","NA","NA","NA","NA",null,{"v":1.116464,"d":"1.12"},{"v":0.692377,"d":"0.69"},{"v":1.61250879217536,"d":"1.61"},{"v":0.689307026826255,"d":"0.69"},1,1,"up","no"]
["ENSG00000259614","AC087477.6","ENST00000559595","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000241889","AC079944.2","ENST00000478867","NA","NA","NA","NA",null,0,{"v":0.275962,"d":"0.28"},"-inf","-inf",1,1,"down","no"]
["ENSG00000279766","AC067931.1","ENST00000624190","NA","NA","NA","NA",null,0,{"v":0.050018,"d":"0.05"},"-inf","-inf",1,1,"down","no"]
["ENSG00000211626","IGKV6D-41","ENST00000390271","GO:0002377(immunoglobulin production);GO:0006955(immune response);GO:0005615(extracellular space)","NA","NA","NA","immunoglobulin kappa variable 6D-41 (non-functional) [Source:HGNC Symbol;Acc:HGNC:5838]",{"v":0.072064,"d":"0.07"},0,"inf","inf",1,1,"up","no"]
["ENSG00000241737","FAM90A23P","ENST00000400136","NA","NA","NA","NA","family with sequence similarity 90 member A23, pseudogene [Source:HGNC Symbol;Acc:HGNC:32271]",0,0,1,0,1,1,"no","no"]
["ENSG00000183628","DGCR6","ENST00000608842;ENST00000427407;ENST00000331444;ENST00000436645","GO:0005634(nucleus);GO:0003674(molecular_function);GO:0007155(cell adhesion);GO:0009887(animal organ morphogenesis);GO:0005578(proteinaceous extracellular matrix);GO:0005578(proteinaceous extracellular matrix)","NA","NA","NA","DiGeorge syndrome critical region gene 6 [Source:HGNC Symbol;Acc:HGNC:2846]",{"v":0.113919694792854,"d":"0.11"},{"v":0.303293523375143,"d":"0.30"},{"v":0.375608728881253,"d":"0.38"},{"v":-1.41269750429353,"d":"-1.41"},1,1,"down","no"]
["ENSG00000165028","NIPSNAP3B","ENST00000461177;ENST00000374762;ENST00000460936","GO:0005739(mitochondrion);GO:0005739(mitochondrion)","NA","NA","NA","nipsnap homolog 3B [Source:HGNC Symbol;Acc:HGNC:23641]",{"v":0.20136266620753,"d":"0.20"},{"v":0.337345791551882,"d":"0.34"},{"v":0.596902855320077,"d":"0.60"},{"v":-0.744431939866168,"d":"-0.74"},1,1,"down","no"]
["ENSG00000174448","STARD6","ENST00000581310","GO:0006810(transport);GO:0008289(lipid binding);GO:0006869(lipid transport);GO:0005739(mitochondrion);GO:0015485(cholesterol binding)","NA","NA","NA","StAR related lipid transfer domain containing 6 [Source:HGNC Symbol;Acc:HGNC:18066]",0,0,1,0,1,1,"no","no"]
["ENSG00000272979","AC093388.1","ENST00000609166","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000178662","CSRNP3","ENST00000314499","GO:0005634(nucleus);GO:0006366(transcription from RNA polymerase II promoter);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0006915(apoptotic process);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0043065(positive regulation of apoptotic process);GO:0010923(negative regulation of phosphatase activity);GO:0001228(transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding);GO:0043565(sequence-specific DNA binding)","NA","NA","NA","cysteine and serine rich nuclear protein 3 [Source:HGNC Symbol;Acc:HGNC:30729]",0,0,1,0,1,1,"no","no"]
["ENSG00000271153","RPL23AP88","ENST00000605759","NA","NA","NA","NA","ribosomal protein L23a pseudogene 88 [Source:HGNC Symbol;Acc:HGNC:51579]",{"v":0.112639,"d":"0.11"},{"v":0.082019,"d":"0.08"},{"v":1.37332813128665,"d":"1.37"},{"v":0.457676371895229,"d":"0.46"},1,1,"up","no"]
["ENSG00000233917","POTEB","ENST00000439682","NA","NA","NA","NA","POTE ankyrin domain family member B [Source:HGNC Symbol;Acc:HGNC:33734]",0,0,1,0,1,1,"no","no"]
["ENSG00000257279","AC127164.1","ENST00000548738","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["MSTRG.13304","NHSL1","ENST00000427025;ENST00000343505;ENST00000491526;ENST00000342260","GO:0016020(membrane);GO:0097475(motor neuron migration);GO:0097475(motor neuron migration)","NA","NA","NA","NHS like 1 [Source:HGNC Symbol;Acc:HGNC:21021]",{"v":0.0546330511383137,"d":"0.05"},{"v":0.0291110856881364,"d":"0.03"},{"v":1.87670950247583,"d":"1.88"},{"v":0.908205351408949,"d":"0.91"},1,1,"up","no"]
["ENSG00000196341","OR8D1","ENST00000357821","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0004930(G-protein coupled receptor activity);GO:0007186(G-protein coupled receptor signaling pathway);GO:0005886(plasma membrane);GO:0004871(signal transducer activity);GO:0007165(signal transduction);GO:0004984(olfactory receptor activity);GO:0007608(sensory perception of smell);GO:0050896(response to stimulus);GO:0050911(detection of chemical stimulus involved in sensory perception of smell);GO:0005549(odorant binding)","04740(Olfactory transduction)","K04257","NA","olfactory receptor family 8 subfamily D member 1 [Source:HGNC Symbol;Acc:HGNC:8481]",0,0,1,0,1,1,"no","no"]
["ENSG00000115884","SDC1","ENST00000381150;ENST00000482879","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005576(extracellular region);GO:0050900(leukocyte migration);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0070062(extracellular exosome);GO:0005887(integral component of plasma membrane);GO:0008022(protein C-terminus binding);GO:0042060(wound healing);GO:0009986(cell surface);GO:0016477(cell migration);GO:0043202(lysosomal lumen);GO:0001523(retinoid metabolic process);GO:0006024(glycosaminoglycan biosynthetic process);GO:0006027(glycosaminoglycan catabolic process);GO:0030203(glycosaminoglycan metabolic process);GO:0005796(Golgi lumen);GO:1903543(positive regulation of exosomal secretion);GO:1903553(positive regulation of extracellular exosome assembly);GO:0048627(myoblast development);GO:0055002(striated muscle cell development);GO:0001657(ureteric bud development);GO:0006954(inflammatory response);GO:0009636(response to toxic substance);GO:0010033(response to organic substance);GO:0042476(odontogenesis);GO:0042542(response to hydrogen peroxide);GO:0051384(response to glucocorticoid);GO:0051591(response to cAMP);GO:0051592(response to calcium ion);GO:0060009(Sertoli cell development);GO:0060070(canonical Wnt signaling pathway);GO:0009897(external side of plasma membrane);GO:0043234(protein complex);GO:0043234(protein complex)","04512(ECM-receptor interaction);04514(Cell adhesion molecules (CAMs));05205(Proteoglycans in cancer);05418(Fluid shear stress and atherosclerosis);05144(Malaria);05144(Malaria)","K06257","NA","syndecan 1 [Source:HGNC Symbol;Acc:HGNC:10658]",{"v":0.0515693749652295,"d":"0.05"},{"v":0.0141563349095967,"d":"0.01"},{"v":3.64284790481117,"d":"3.64"},{"v":1.86506676132957,"d":"1.87"},1,1,"up","no"]
["MSTRG.856","AC239860.1","ENST00000444680","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["MSTRG.8059","AC008738.3","ENST00000589932","NA","NA","NA","NA",null,{"v":0.05439,"d":"0.05"},0,"inf","inf",1,1,"up","no"]
["MSTRG.698","AC093423.2","ENST00000429074","NA","NA","NA","NA",null,{"v":0.2447,"d":"0.24"},0,"inf","inf",1,1,"up","no"]
["ENSG00000264269","AC016866.1","ENST00000584252","NA","NA","NA","NA",null,{"v":0.175695,"d":"0.18"},{"v":0.048439,"d":"0.05"},{"v":3.62713928858977,"d":"3.63"},{"v":1.8588321484235,"d":"1.86"},1,1,"up","no"]
["MSTRG.2526","MIR6879","ENST00000610949","NA","NA","NA","NA","microRNA 6879 [Source:HGNC Symbol;Acc:HGNC:49957]",0,0,1,0,1,1,"no","no"]
["ENSG00000267934","AC010300.1","ENST00000600671","NA","NA","NA","NA",null,0,{"v":0.009749,"d":"0.01"},"-inf","-inf",1,1,"down","no"]
["ENSG00000230606","AC092683.1","ENST00000612970;ENST00000620023;ENST00000604397;ENST00000609751;ENST00000620272;ENST00000610408;ENST00000431244;ENST00000621982;ENST00000620051","NA","NA","NA","NA",null,{"v":0.481229635089049,"d":"0.48"},{"v":0.080618843690792,"d":"0.08"},{"v":5.96919545180742,"d":"5.97"},{"v":2.57753649331474,"d":"2.58"},1,1,"up","no"]
["ENSG00000132681","ATP1A4","ENST00000368081;ENST00000469023","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0016787(hydrolase activity);GO:0006811(ion transport);GO:0006813(potassium ion transport);GO:0005886(plasma membrane);GO:0006814(sodium ion transport);GO:0015991(ATP hydrolysis coupled proton transport);GO:0005887(integral component of plasma membrane);GO:0005391(sodium:potassium-exchanging ATPase activity);GO:0010248(establishment or maintenance of transmembrane electrochemical gradient);GO:0034220(ion transmembrane transport);GO:1903779(regulation of cardiac conduction);GO:0005890(sodium:potassium-exchanging ATPase complex);GO:0030317(flagellated sperm motility);GO:0007283(spermatogenesis);GO:0009566(fertilization);GO:0030641(regulation of cellular pH);GO:0042391(regulation of membrane potential);GO:0042391(regulation of membrane potential)","04024(cAMP signaling pathway);04022(cGMP - PKG signaling pathway);04911(Insulin secretion);04918(Thyroid hormone synthesis);04919(Thyroid hormone signaling pathway);04925(Aldosterone synthesis and secretion);04260(Cardiac muscle contraction);04261(Adrenergic signaling in cardiomyocytes);04970(Salivary secretion);04971(Gastric acid secretion);04972(Pancreatic secretion);04976(Bile secretion);04973(Carbohydrate digestion and absorption);04974(Protein digestion and absorption);04978(Mineral absorption);04960(Aldosterone-regulated sodium reabsorption);04961(Endocrine and other factor-regulated calcium reabsorption);04964(Proximal tubule bicarbonate reclamation);04964(Proximal tubule bicarbonate reclamation)","K01539","EC:3.6.3.9","ATPase Na+/K+ transporting subunit alpha 4 [Source:HGNC Symbol;Acc:HGNC:14073]",0,{"v":0.00809871674092934,"d":"0.01"},"-inf","-inf",1,1,"down","no"]
["ENSG00000115488","NEU2","ENST00000233840","GO:0005737(cytoplasm);GO:0016787(hydrolase activity);GO:0006629(lipid metabolic process);GO:0016042(lipid catabolic process);GO:0005515(protein binding);GO:0008152(metabolic process);GO:0016798(hydrolase activity, acting on glycosyl bonds);GO:0004308(exo-alpha-sialidase activity);GO:0005975(carbohydrate metabolic process);GO:0016020(membrane);GO:0005829(cytosol);GO:0006687(glycosphingolipid metabolic process);GO:0043231(intracellular membrane-bounded organelle);GO:0052794(exo-alpha-(2->3)-sialidase activity);GO:0052795(exo-alpha-(2->6)-sialidase activity);GO:0052796(exo-alpha-(2->8)-sialidase activity);GO:0006689(ganglioside catabolic process);GO:0009313(oligosaccharide catabolic process);GO:0051692(cellular oligosaccharide catabolic process);GO:1902494(catalytic complex)","00600(Sphingolipid metabolism);00511(Other glycan degradation)","K12357","EC:3.2.1.18","neuraminidase 2 [Source:HGNC Symbol;Acc:HGNC:7759]",0,0,1,0,1,1,"no","no"]
["ENSG00000224282","AC010469.1","ENST00000463864","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000183248","PRR36","ENST00000618550","NA","NA","NA","NA","proline rich 36 [Source:HGNC Symbol;Acc:HGNC:26172]",{"v":0.035763,"d":"0.04"},0,"inf","inf",1,1,"up","no"]
["ENSG00000228445","UGT1A2P","ENST00000454886","NA","NA","NA","NA","UDP glucuronosyltransferase family 1 member A2, pseudogene [Source:HGNC Symbol;Acc:HGNC:12534]",0,0,1,0,1,1,"no","no"]
["ENSG00000214018","RRM2P3","ENST00000426279","NA","NA","NA","NA","ribonucleotide reductase M2 polypeptide pseudogene 3 [Source:HGNC Symbol;Acc:HGNC:10455]",0,0,1,0,1,1,"no","no"]
["ENSG00000258949","AL049870.3","ENST00000555157","NA","NA","NA","NA",null,{"v":0.282707,"d":"0.28"},{"v":0.230919,"d":"0.23"},{"v":1.22426911601038,"d":"1.22"},{"v":0.291920722783915,"d":"0.29"},1,1,"up","no"]
["MSTRG.11971","AC012640.2","ENST00000561606","NA","NA","NA","NA",null,{"v":0.324261,"d":"0.32"},{"v":0.392019,"d":"0.39"},{"v":0.827156336810206,"d":"0.83"},{"v":-0.2737680629216,"d":"-0.27"},1,1,"down","no"]
["ENSG00000268970","AC022150.2","ENST00000596451","NA","NA","NA","NA",null,{"v":0.912907,"d":"0.91"},{"v":0.334554,"d":"0.33"},{"v":2.72872839661161,"d":"2.73"},{"v":1.44822880342049,"d":"1.45"},1,1,"up","no"]
["ENSG00000225337","AL353608.1","ENST00000419576","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000169397","RNASE3","ENST00000304639","GO:0003676(nucleic acid binding);GO:0016787(hydrolase activity);GO:0090305(nucleic acid phosphodiester bond hydrolysis);GO:0005576(extracellular region);GO:0004519(endonuclease activity);GO:0090501(RNA phosphodiester bond hydrolysis);GO:0004518(nuclease activity);GO:0005615(extracellular space);GO:0045087(innate immune response);GO:0042742(defense response to bacterium);GO:0070062(extracellular exosome);GO:0050829(defense response to Gram-negative bacterium);GO:0002227(innate immune response in mucosa);GO:0019731(antibacterial humoral response);GO:0050830(defense response to Gram-positive bacterium);GO:0061844(antimicrobial humoral immune response mediated by antimicrobial peptide);GO:0043312(neutrophil degranulation);GO:0001530(lipopolysaccharide binding);GO:0019730(antimicrobial humoral response);GO:0035578(azurophil granule lumen);GO:0004540(ribonuclease activity);GO:0006401(RNA catabolic process);GO:0043152(induction of bacterial agglutination)","05310(Asthma)","K10787","EC:3.1.27.-","ribonuclease A family member 3 [Source:HGNC Symbol;Acc:HGNC:10046]",{"v":0.147555,"d":"0.15"},{"v":0.417311,"d":"0.42"},{"v":0.353585215822252,"d":"0.35"},{"v":-1.49987014115864,"d":"-1.50"},1,1,"down","no"]
["MSTRG.6516","AC087294.1","ENST00000580291;ENST00000439136","NA","NA","NA","NA",null,{"v":0.157600821593153,"d":"0.16"},0,"inf","inf",1,1,"up","no"]
["ENSG00000205678","TECRL","ENST00000509536","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016627(oxidoreductase activity, acting on the CH-CH group of donors);GO:0006629(lipid metabolic process);GO:0055114(oxidation-reduction process);GO:0016491(oxidoreductase activity);GO:0005783(endoplasmic reticulum);GO:0042761(very long-chain fatty acid biosynthetic process)","NA","NA","NA","trans-2,3-enoyl-CoA reductase like [Source:HGNC Symbol;Acc:HGNC:27365]",0,0,1,0,1,1,"no","no"]
["ENSG00000163705","FANCD2OS","ENST00000453223","NA","NA","NA","NA","FANCD2 opposite strand [Source:HGNC Symbol;Acc:HGNC:28623]",0,0,1,0,1,1,"no","no"]
["ENSG00000197019","SERTAD1","ENST00000357949","GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0030308(negative regulation of cell growth);GO:0008284(positive regulation of cell proliferation);GO:0000079(regulation of cyclin-dependent protein serine/threonine kinase activity);GO:0045893(positive regulation of transcription, DNA-templated);GO:0045944(positive regulation of transcription from RNA polymerase II promoter)","NA","NA","NA","SERTA domain containing 1 [Source:HGNC Symbol;Acc:HGNC:17932]",{"v":2.697808,"d":"2.70"},{"v":0.200163,"d":"0.20"},{"v":13.4780553848613,"d":"13.48"},{"v":3.75254045424132,"d":"3.75"},1,1,"up","no"]
["ENSG00000270751","FBXW7-AS1","ENST00000605147","NA","NA","NA","NA","FBXW7 antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:52397]",0,0,1,0,1,1,"no","no"]
["MSTRG.1555","CELF2-AS1","ENST00000379256","NA","NA","NA","NA","CELF2 antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:23515]",{"v":1.648758,"d":"1.65"},{"v":0.299822,"d":"0.30"},{"v":5.49912281286897,"d":"5.50"},{"v":2.45920150691874,"d":"2.46"},1,1,"up","no"]
["ENSG00000274267","HIST1H3B","ENST00000621411","GO:0005634(nucleus);GO:0016020(membrane);GO:0003677(DNA binding);GO:0046982(protein heterodimerization activity);GO:0006334(nucleosome assembly);GO:0000786(nucleosome);GO:0005694(chromosome);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0005654(nucleoplasm);GO:0045296(cadherin binding);GO:0070062(extracellular exosome);GO:0044267(cellular protein metabolic process);GO:1902036(regulation of hematopoietic stem cell differentiation);GO:0043234(protein complex);GO:0000784(nuclear chromosome, telomeric region);GO:0045815(positive regulation of gene expression, epigenetic);GO:0042393(histone binding);GO:0038111(interleukin-7-mediated signaling pathway);GO:0045652(regulation of megakaryocyte differentiation);GO:0006335(DNA replication-dependent nucleosome assembly);GO:0007596(blood coagulation);GO:0000228(nuclear chromosome);GO:0060964(regulation of gene silencing by miRNA);GO:0000183(chromatin silencing at rDNA);GO:0045814(negative regulation of gene expression, epigenetic);GO:0051290(protein heterotetramerization);GO:0000788(nuclear nucleosome);GO:0031492(nucleosomal DNA binding);GO:0006325(chromatin organization);GO:0032200(telomere organization);GO:0060968(regulation of gene silencing)","05202(Transcriptional misregulation in cancers);05322(Systemic lupus erythematosus);05034(Alcoholism)","K11253","NA","histone cluster 1 H3 family member b [Source:HGNC Symbol;Acc:HGNC:4776]",0,{"v":0.123824,"d":"0.12"},"-inf","-inf",1,1,"down","no"]
["ENSG00000254281","AP003354.2","ENST00000517983","NA","NA","NA","NA",null,{"v":0.620272,"d":"0.62"},{"v":0.383903,"d":"0.38"},{"v":1.61569979916802,"d":"1.62"},{"v":0.692159166849351,"d":"0.69"},1,1,"up","no"]
["MSTRG.3796","AC063943.1","ENST00000465434","NA","NA","NA","NA",null,{"v":0.045885,"d":"0.05"},0,"inf","inf",1,1,"up","no"]
["ENSG00000275038","AC091980.2","ENST00000619056","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000265282","AC005828.4","ENST00000584608","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000197444","OGDHL","ENST00000374103;ENST00000490844","GO:0046872(metal ion binding);GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0006099(tricarboxylic acid cycle);GO:0006096(glycolytic process);GO:0008152(metabolic process);GO:0005739(mitochondrion);GO:0016624(oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor);GO:0005515(protein binding);GO:0005759(mitochondrial matrix);GO:0004591(oxoglutarate dehydrogenase (succinyl-transferring) activity);GO:0030976(thiamine pyrophosphate binding);GO:0045252(oxoglutarate dehydrogenase complex);GO:0045252(oxoglutarate dehydrogenase complex)","00020(Citrate cycle (TCA cycle));00310(Lysine degradation);00380(Tryptophan metabolism);00380(Tryptophan metabolism)","K00164","EC:1.2.4.2","oxoglutarate dehydrogenase like [Source:HGNC Symbol;Acc:HGNC:25590]",0,0,1,0,1,1,"no","no"]
["ENSG00000224747","MTCYBP21","ENST00000443300","NA","NA","NA","NA","mitochondrially encoded cytochrome b pseudogene 21 [Source:HGNC Symbol;Acc:HGNC:51977]",0,0,1,0,1,1,"no","no"]
["ENSG00000257671","KRT7-AS","ENST00000546686","NA","NA","NA","NA","KRT7 antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:52643]",0,0,1,0,1,1,"no","no"]
["MSTRG.6177","AC092718.1","ENST00000501068","NA","NA","NA","NA",null,0,{"v":0.075732,"d":"0.08"},"-inf","-inf",1,1,"down","no"]
["ENSG00000214946","TBC1D26","ENST00000491819;ENST00000580970","GO:0005096(GTPase activator activity);GO:0017137(Rab GTPase binding);GO:0006886(intracellular protein transport);GO:0031338(regulation of vesicle fusion);GO:0090630(activation of GTPase activity);GO:0005622(intracellular);GO:0012505(endomembrane system);GO:0012505(endomembrane system)","NA","NA","NA","TBC1 domain family member 26 [Source:HGNC Symbol;Acc:HGNC:28745]",{"v":0.00466043779610458,"d":"0.00"},{"v":0.00892995683453237,"d":"0.01"},{"v":0.521888054159741,"d":"0.52"},{"v":-0.938187715350356,"d":"-0.94"},1,1,"down","no"]
["ENSG00000228526","MIR34AHG","ENST00000635687","NA","NA","NA","NA","MIR34A host gene [Source:HGNC Symbol;Acc:HGNC:51913]",{"v":0.0347096580616933,"d":"0.03"},{"v":0.0111461144169766,"d":"0.01"},{"v":3.11405901314158,"d":"3.11"},{"v":1.6387962845454,"d":"1.64"},1,1,"up","no"]
["ENSG00000259261","IGHV4OR15-8","ENST00000557788","NA","NA","NA","NA","immunoglobulin heavy variable 4/OR15-8 (non-functional) [Source:HGNC Symbol;Acc:HGNC:5658]",{"v":0.038783,"d":"0.04"},{"v":0.153541,"d":"0.15"},{"v":0.252590513283097,"d":"0.25"},{"v":-1.98512763904156,"d":"-1.99"},1,1,"down","no"]
["ENSG00000266900","AC027514.1","ENST00000588561","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000213131","YWHAZP4","ENST00000392459","NA","NA","NA","NA","tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta pseudogene 4 [Source:HGNC Symbol;Acc:HGNC:30851]",0,0,1,0,1,1,"no","no"]
["ENSG00000157087","ATP2B2","ENST00000460129;ENST00000360273","GO:0006810(transport);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0016787(hydrolase activity);GO:0006811(ion transport);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0005388(calcium-transporting ATPase activity);GO:0006816(calcium ion transport);GO:0070588(calcium ion transmembrane transport);GO:0099132(ATP hydrolysis coupled cation transmembrane transport);GO:0030054(cell junction);GO:0045202(synapse);GO:0005516(calmodulin binding);GO:0005887(integral component of plasma membrane);GO:0070062(extracellular exosome);GO:0034220(ion transmembrane transport);GO:0007605(sensory perception of sound);GO:1903779(regulation of cardiac conduction);GO:0030182(neuron differentiation);GO:0043231(intracellular membrane-bounded organelle);GO:0030165(PDZ domain binding);GO:0051480(regulation of cytosolic calcium ion concentration);GO:0051480(regulation of cytosolic calcium ion concentration)","04020(Calcium signaling pathway);04024(cAMP signaling pathway);04022(cGMP - PKG signaling pathway);04925(Aldosterone synthesis and secretion);04261(Adrenergic signaling in cardiomyocytes);04970(Salivary secretion);04972(Pancreatic secretion);04972(Pancreatic secretion)","K05850","EC:3.6.3.8","ATPase plasma membrane Ca2+ transporting 2 [Source:HGNC Symbol;Acc:HGNC:815]",0,0,1,0,1,1,"no","no"]
["ENSG00000164362","TERT","ENST00000484238;ENST00000310581","GO:0010629(negative regulation of gene expression);GO:2000773(negative regulation of cellular senescence);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0005654(nucleoplasm);GO:0016740(transferase activity);GO:0003677(DNA binding);GO:0030529(intracellular ribonucleoprotein complex);GO:0005694(chromosome);GO:0005515(protein binding);GO:0016779(nucleotidyltransferase activity);GO:0005730(nucleolus);GO:0000781(chromosome, telomeric region);GO:0000784(nuclear chromosome, telomeric region);GO:0000723(telomere maintenance);GO:0042803(protein homodimerization activity);GO:1904837(beta-catenin-TCF complex assembly);GO:0016605(PML body);GO:0042645(mitochondrial nucleoid);GO:0030177(positive regulation of Wnt signaling pathway);GO:0003720(telomerase activity);GO:0003721(telomerase RNA reverse transcriptase activity);GO:0003968(RNA-directed 5'-3' RNA polymerase activity);GO:0098680(template-free RNA nucleotidyltransferase);GO:0000049(tRNA binding);GO:0001223(transcription coactivator binding);GO:0003723(RNA binding);GO:0003964(RNA-directed DNA polymerase activity);GO:0008022(protein C-terminus binding);GO:0042162(telomeric DNA binding);GO:0047485(protein N-terminus binding);GO:0051087(chaperone binding);GO:0070034(telomerase RNA binding);GO:0001172(transcription, RNA-templated);GO:0006278(RNA-dependent DNA biosynthetic process);GO:0007004(telomere maintenance via telomerase);GO:0007005(mitochondrion organization);GO:0022616(DNA strand elongation);GO:0030422(production of siRNA involved in RNA interference);GO:0031647(regulation of protein stability);GO:0032092(positive regulation of protein binding);GO:0032774(RNA biosynthetic process);GO:0042635(positive regulation of hair cycle);GO:0043066(negative regulation of apoptotic process);GO:0043524(negative regulation of neuron apoptotic process);GO:0045766(positive regulation of angiogenesis);GO:0046326(positive regulation of glucose import);GO:0046686(response to cadmium ion);GO:0051000(positive regulation of nitric-oxide synthase activity);GO:0060253(negative regulation of glial cell proliferation);GO:0070200(establishment of protein localization to telomere);GO:0071456(cellular response to hypoxia);GO:0071897(DNA biosynthetic process);GO:0090399(replicative senescence);GO:1900087(positive regulation of G1/S transition of mitotic cell cycle);GO:1902895(positive regulation of pri-miRNA transcription from RNA polymerase II promoter);GO:1903620(positive regulation of transdifferentiation);GO:1903704(negative regulation of production of siRNA involved in RNA interference);GO:1904707(positive regulation of vascular smooth muscle cell proliferation);GO:1904751(positive regulation of protein localization to nucleolus);GO:1904754(positive regulation of vascular associated smooth muscle cell migration);GO:2000352(negative regulation of endothelial cell apoptotic process);GO:2000648(positive regulation of stem cell proliferation);GO:2001240(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand);GO:0000333(telomerase catalytic core complex);GO:0000783(nuclear telomere cap complex);GO:0005697(telomerase holoenzyme complex);GO:0005739(mitochondrion);GO:0005886(plasma membrane);GO:0031379(RNA-directed RNA polymerase complex);GO:1990572(TERT-RMRP complex);GO:1990572(TERT-RMRP complex)","05200(Pathways in cancer);05225(Hepatocellular carcinoma);05226(Gastric cancer);05166(HTLV-I infection);05165(Human papillomavirus infection);05165(Human papillomavirus infection)","K11126","EC:2.7.7.49","telomerase reverse transcriptase [Source:HGNC Symbol;Acc:HGNC:11730]",{"v":0.0115081243500867,"d":"0.01"},0,"inf","inf",1,1,"up","no"]
["ENSG00000125879","OTOR","ENST00000246081","GO:0005576(extracellular region);GO:0007605(sensory perception of sound);GO:0001502(cartilage condensation)","NA","NA","NA","otoraplin [Source:HGNC Symbol;Acc:HGNC:8517]",0,0,1,0,1,1,"no","no"]
["MSTRG.8357","SIGLEC18P","ENST00000602271","NA","NA","NA","NA","sialic acid binding Ig like lectin 18, pseudogene [Source:HGNC Symbol;Acc:HGNC:15491]",{"v":0.093348,"d":"0.09"},{"v":0.055987,"d":"0.06"},{"v":1.66731562684195,"d":"1.67"},{"v":0.737527235804349,"d":"0.74"},1,1,"up","no"]
["ENSG00000263013","AC133065.4","ENST00000570440","NA","NA","NA","NA",null,0,{"v":0.087384,"d":"0.09"},"-inf","-inf",1,1,"down","no"]
["MSTRG.9021","AC007278.1","ENST00000450893","NA","NA","NA","NA",null,{"v":0.488621,"d":"0.49"},{"v":0.206908,"d":"0.21"},{"v":2.36153749492528,"d":"2.36"},{"v":1.23972644182484,"d":"1.24"},1,1,"up","no"]
["ENSG00000105523","FAM83E","ENST00000263266","GO:0019901(protein kinase binding)","NA","NA","NA","family with sequence similarity 83 member E [Source:HGNC Symbol;Acc:HGNC:25972]",0,0,1,0,1,1,"no","no"]
["MSTRG.15458","RAP2C-AS1","ENST00000441399;ENST00000421483","NA","NA","NA","NA","RAP2C antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:40957]",{"v":0.288517314196833,"d":"0.29"},{"v":0.0558066784502262,"d":"0.06"},{"v":5.16994241924218,"d":"5.17"},{"v":2.37014821246741,"d":"2.37"},1,1,"up","no"]
["ENSG00000213938","SEPHS1P6","ENST00000443084","NA","NA","NA","NA","selenophosphate synthetase 1 pseudogene 6 [Source:HGNC Symbol;Acc:HGNC:42168]",0,0,1,0,1,1,"no","no"]
["MSTRG.5125","MTND5P32","ENST00000560711","NA","NA","NA","NA","mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 5 pseudogene 32 [Source:HGNC Symbol;Acc:HGNC:51951]",0,{"v":0.024314,"d":"0.02"},"-inf","-inf",1,1,"down","no"]
["ENSG00000236703","MYB-AS1","ENST00000455534","NA","NA","NA","NA","MYB antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:37457]",0,{"v":0.040733,"d":"0.04"},"-inf","-inf",1,1,"down","no"]
["MSTRG.264","SDHDP6","ENST00000414693","NA","NA","NA","NA","succinate dehydrogenase complex subunit D pseudogene 6 [Source:HGNC Symbol;Acc:HGNC:10689]",0,0,1,0,1,1,"no","no"]
["ENSG00000132259","CNGA4","ENST00000379936;ENST00000533426","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0055085(transmembrane transport);GO:0000166(nucleotide binding);GO:0005216(ion channel activity);GO:0006811(ion transport);GO:0034220(ion transmembrane transport);GO:0071805(potassium ion transmembrane transport);GO:0030552(cAMP binding);GO:0007608(sensory perception of smell);GO:0050896(response to stimulus);GO:0005887(integral component of plasma membrane);GO:0005249(voltage-gated potassium channel activity);GO:0000139(Golgi membrane);GO:0042391(regulation of membrane potential);GO:0030660(Golgi-associated vesicle membrane);GO:0060170(ciliary membrane);GO:0060170(ciliary membrane)","04024(cAMP signaling pathway);04740(Olfactory transduction);04740(Olfactory transduction)","K04951","NA","cyclic nucleotide gated channel alpha 4 [Source:HGNC Symbol;Acc:HGNC:2152]",{"v":0.105418029995385,"d":"0.11"},{"v":0.0234849746192893,"d":"0.02"},{"v":4.48874362030608,"d":"4.49"},{"v":2.16631169743951,"d":"2.17"},1,1,"up","no"]
["ENSG00000163449","TMEM169","ENST00000454545;ENST00000406027;ENST00000433112;ENST00000437356","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016021(integral component of membrane)","NA","NA","NA","transmembrane protein 169 [Source:HGNC Symbol;Acc:HGNC:25130]",{"v":0.165512655457552,"d":"0.17"},{"v":0.077987769570011,"d":"0.08"},{"v":2.1222898971225,"d":"2.12"},{"v":1.08562173663681,"d":"1.09"},1,1,"up","no"]
["MSTRG.7358","AC132872.4","ENST00000624920","NA","NA","NA","NA",null,0,{"v":0.459845,"d":"0.46"},"-inf","-inf",1,1,"down","no"]
["ENSG00000233412","OR5H15","ENST00000641450","NA","04740(Olfactory transduction)","K04257","NA","olfactory receptor family 5 subfamily H member 15 [Source:HGNC Symbol;Acc:HGNC:31287]",0,0,1,0,1,1,"no","no"]
["ENSG00000230358","SPDYE21P","ENST00000413323","NA","NA","NA","NA","speedy/RINGO cell cycle regulator family member E21, pseudogene [Source:HGNC Symbol;Acc:HGNC:51517]",{"v":0.358348,"d":"0.36"},{"v":2.72E-4,"d":"0.00"},{"v":1317.45588235294,"d":"1317.46"},{"v":10.3635389358025,"d":"10.36"},1,1,"up","no"]
["MSTRG.5957","ADGRG5","MSTRG.5957.1","NA","NA","NA","NA",null,{"v":0.726955,"d":"0.73"},{"v":0.437781,"d":"0.44"},{"v":1.6605448843143,"d":"1.66"},{"v":0.731656719228757,"d":"0.73"},1,1,"up","no"]
["ENSG00000230311","TOMM20P4","ENST00000427861","NA","NA","NA","NA","TOMM20 pseudogene 4 [Source:HGNC Symbol;Acc:HGNC:50522]",0,{"v":0.228174,"d":"0.23"},"-inf","-inf",1,1,"down","no"]
["MSTRG.447","OXCT2","ENST00000327582","GO:0016740(transferase activity);GO:0008152(metabolic process);GO:0005739(mitochondrion);GO:0008260(3-oxoacid CoA-transferase activity);GO:0008410(CoA-transferase activity);GO:0046952(ketone body catabolic process);GO:0005759(mitochondrial matrix);GO:0031514(motile cilium)","00650(Butanoate metabolism);00072(Synthesis and degradation of ketone bodies);00280(Valine, leucine and isoleucine degradation)","K01027","EC:2.8.3.5","3-oxoacid CoA-transferase 2 [Source:HGNC Symbol;Acc:HGNC:18606]",{"v":0.072727,"d":"0.07"},{"v":0.027778,"d":"0.03"},{"v":2.61815105479156,"d":"2.62"},{"v":1.38854833628694,"d":"1.39"},1,1,"up","no"]
["ENSG00000280021","OR51F1","ENST00000624103;ENST00000380383","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0004930(G-protein coupled receptor activity);GO:0007186(G-protein coupled receptor signaling pathway);GO:0005886(plasma membrane);GO:0004871(signal transducer activity);GO:0007165(signal transduction);GO:0004984(olfactory receptor activity);GO:0007608(sensory perception of smell);GO:0050896(response to stimulus);GO:0050911(detection of chemical stimulus involved in sensory perception of smell);GO:0050911(detection of chemical stimulus involved in sensory perception of smell)","04740(Olfactory transduction);04740(Olfactory transduction)","K04257","NA","olfactory receptor family 51 subfamily F member 1 (gene/pseudogene) [Source:HGNC Symbol;Acc:HGNC:15196]",0,0,1,0,1,1,"no","no"]
["ENSG00000141255","SPATA22","ENST00000573128","GO:0005694(chromosome);GO:0005515(protein binding);GO:0007276(gamete generation);GO:0051321(meiotic cell cycle);GO:0000711(meiotic DNA repair synthesis);GO:0007129(synapsis)","NA","NA","NA","spermatogenesis associated 22 [Source:HGNC Symbol;Acc:HGNC:30705]",0,{"v":0.0355885762237762,"d":"0.04"},"-inf","-inf",1,1,"down","no"]
["MSTRG.13574","AOAH-IT1","ENST00000449672","NA","NA","NA","NA","AOAH intronic transcript 1 [Source:HGNC Symbol;Acc:HGNC:41307]",{"v":0.486775,"d":"0.49"},{"v":0.324434,"d":"0.32"},{"v":1.50038220408465,"d":"1.50"},{"v":0.585330056521059,"d":"0.59"},1,1,"up","no"]
["MSTRG.4434","AL157756.1","ENST00000532515;ENST00000529171","NA","NA","NA","NA",null,{"v":0.0251155491439442,"d":"0.03"},{"v":0.0136631572606214,"d":"0.01"},{"v":1.83819513051568,"d":"1.84"},{"v":0.878289921624202,"d":"0.88"},1,1,"up","no"]
["ENSG00000189037","DUSP21","ENST00000339042","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0016787(hydrolase activity);GO:0005743(mitochondrial inner membrane);GO:0004725(protein tyrosine phosphatase activity);GO:0008138(protein tyrosine/serine/threonine phosphatase activity);GO:0016791(phosphatase activity);GO:0006470(protein dephosphorylation);GO:0016311(dephosphorylation);GO:0005739(mitochondrion);GO:0004721(phosphoprotein phosphatase activity);GO:0005515(protein binding);GO:0017017(MAP kinase tyrosine/serine/threonine phosphatase activity);GO:0000188(inactivation of MAPK activity);GO:0035335(peptidyl-tyrosine dephosphorylation);GO:0005759(mitochondrial matrix);GO:0031314(extrinsic component of mitochondrial inner membrane)","NA","NA","NA","dual specificity phosphatase 21 [Source:HGNC Symbol;Acc:HGNC:20476]",0,0,1,0,1,1,"no","no"]
["ENSG00000145248","SLC10A4","ENST00000273861","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0015293(symporter activity);GO:0055085(transmembrane transport);GO:0006811(ion transport);GO:0005886(plasma membrane);GO:0006814(sodium ion transport);GO:0015721(bile acid and bile salt transport);GO:0008508(bile acid:sodium symporter activity)","NA","NA","NA","solute carrier family 10 member 4 [Source:HGNC Symbol;Acc:HGNC:22980]",{"v":0.059352,"d":"0.06"},0,"inf","inf",1,1,"up","no"]
["ENSG00000203734","ECT2L","ENST00000541398","GO:0005089(Rho guanyl-nucleotide exchange factor activity);GO:0035023(regulation of Rho protein signal transduction);GO:0043547(positive regulation of GTPase activity);GO:0005085(guanyl-nucleotide exchange factor activity)","NA","NA","NA","epithelial cell transforming 2 like [Source:HGNC Symbol;Acc:HGNC:21118]",{"v":0.0186378010380623,"d":"0.02"},{"v":0.00502883239619377,"d":"0.01"},{"v":3.70618854829382,"d":"3.71"},{"v":1.88993627876643,"d":"1.89"},1,1,"up","no"]
["MSTRG.4701","SNORA28","ENST00000606769","NA","NA","NA","NA","small nucleolar RNA, H/ACA box 28 [Source:HGNC Symbol;Acc:HGNC:32618]",{"v":0.664599,"d":"0.66"},0,"inf","inf",1,1,"up","no"]
["ENSG00000268628","AL121761.2","ENST00000598007","NA","NA","NA","NA",null,{"v":0.128932,"d":"0.13"},0,"inf","inf",1,1,"up","no"]
["ENSG00000250072","AC091940.1","ENST00000515304;ENST00000512007;ENST00000507318;ENST00000515519","NA","NA","NA","NA",null,{"v":0.0245152594481799,"d":"0.02"},{"v":0.0168788868536981,"d":"0.02"},{"v":1.45242157617809,"d":"1.45"},{"v":0.538460267097308,"d":"0.54"},1,1,"up","no"]
["ENSG00000255310","AF131215.5","ENST00000530248","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["MSTRG.10515","CSDC2","ENST00000306149;ENST00000460790","GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0006397(mRNA processing);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0003730(mRNA 3'-UTR binding);GO:0043488(regulation of mRNA stability);GO:0008134(transcription factor binding);GO:0008134(transcription factor binding)","NA","NA","NA","cold shock domain containing C2 [Source:HGNC Symbol;Acc:HGNC:30359]",0,{"v":0.0156588621538462,"d":"0.02"},"-inf","-inf",1,1,"down","no"]
["ENSG00000272601","AC010655.3","ENST00000478818","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000128262","POM121L9P","ENST00000414583;ENST00000441984","NA","NA","NA","NA","POM121 transmembrane nucleoporin like 9, pseudogene [Source:HGNC Symbol;Acc:HGNC:30080]",{"v":0.0103407724352735,"d":"0.01"},0,"inf","inf",1,1,"up","no"]
["ENSG00000143127","ITGA10","ENST00000369304","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0046872(metal ion binding);GO:0007155(cell adhesion);GO:0007229(integrin-mediated signaling pathway);GO:0008305(integrin complex);GO:0005886(plasma membrane);GO:0030198(extracellular matrix organization);GO:0007160(cell-matrix adhesion);GO:0005518(collagen binding);GO:0098639(collagen binding involved in cell-matrix adhesion);GO:0034680(integrin alpha10-beta1 complex)","04151(PI3K-Akt signaling pathway);04512(ECM-receptor interaction);04510(Focal adhesion);04810(Regulation of actin cytoskeleton);05410(Hypertrophic cardiomyopathy (HCM));05412(Arrhythmogenic right ventricular cardiomyopathy (ARVC));05414(Dilated cardiomyopathy (DCM));05165(Human papillomavirus infection)","K06586","NA","integrin subunit alpha 10 [Source:HGNC Symbol;Acc:HGNC:6135]",{"v":0.17420131028481,"d":"0.17"},{"v":0.0763529789556962,"d":"0.08"},{"v":2.28152604741054,"d":"2.28"},{"v":1.18999912463849,"d":"1.19"},1,1,"up","no"]
["ENSG00000132793","LPIN3","ENST00000373257;ENST00000632009","GO:0005634(nucleus);GO:0016787(hydrolase activity);GO:0006629(lipid metabolic process);GO:0016311(dephosphorylation);GO:0006631(fatty acid metabolic process);GO:0005789(endoplasmic reticulum membrane);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0008195(phosphatidate phosphatase activity);GO:0009062(fatty acid catabolic process);GO:0003713(transcription coactivator activity);GO:0006656(phosphatidylcholine biosynthetic process);GO:0006646(phosphatidylethanolamine biosynthetic process);GO:0019432(triglyceride biosynthetic process);GO:0019432(triglyceride biosynthetic process)","00561(Glycerolipid metabolism);00564(Glycerophospholipid metabolism);00564(Glycerophospholipid metabolism)","K15728","EC:3.1.3.4","lipin 3 [Source:HGNC Symbol;Acc:HGNC:14451]",{"v":0.0180947975043783,"d":"0.02"},0,"inf","inf",1,1,"up","no"]
["ENSG00000232553","CLK2P1","ENST00000416636","NA","NA","NA","NA","CDC like kinase 2, pseudogene 1 [Source:HGNC Symbol;Acc:HGNC:2070]",0,0,1,0,1,1,"no","no"]
["ENSG00000236814","AC046176.1","ENST00000435260","NA","NA","NA","NA",null,{"v":0.3911,"d":"0.39"},{"v":0.781943,"d":"0.78"},{"v":0.500164334228966,"d":"0.50"},{"v":-0.999525909550668,"d":"-1.00"},1,1,"down","no"]
["ENSG00000111046","MYF6","ENST00000228641","GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0005634(nucleus);GO:0046983(protein dimerization activity);GO:0006355(regulation of transcription, DNA-templated);GO:0006366(transcription from RNA polymerase II promoter);GO:0003677(DNA binding);GO:0007275(multicellular organism development);GO:0030154(cell differentiation);GO:0007517(muscle organ development);GO:0005654(nucleoplasm);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:0001228(transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding);GO:0003705(transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding);GO:0046982(protein heterodimerization activity);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0090575(RNA polymerase II transcription factor complex);GO:0070888(E-box binding);GO:0051149(positive regulation of muscle cell differentiation);GO:0007519(skeletal muscle tissue development);GO:0035914(skeletal muscle cell differentiation);GO:0042693(muscle cell fate commitment);GO:0045663(positive regulation of myoblast differentiation);GO:0048743(positive regulation of skeletal muscle fiber development);GO:1901741(positive regulation of myoblast fusion);GO:0001756(somitogenesis);GO:0043403(skeletal muscle tissue regeneration);GO:0045892(negative regulation of transcription, DNA-templated);GO:0045893(positive regulation of transcription, DNA-templated);GO:0060415(muscle tissue morphogenesis)","NA","NA","NA","myogenic factor 6 [Source:HGNC Symbol;Acc:HGNC:7566]",0,0,1,0,1,1,"no","no"]
["MSTRG.3327","AC004241.1","ENST00000547799;ENST00000552133;ENST00000621159;ENST00000552502;ENST00000553045","NA","NA","NA","NA",null,{"v":0.21360218136477,"d":"0.21"},{"v":0.152452901382906,"d":"0.15"},{"v":1.40110276306437,"d":"1.40"},{"v":0.486562773275054,"d":"0.49"},1,1,"up","no"]
["ENSG00000230910","AL391807.1","ENST00000604392;ENST00000603261","NA","NA","NA","NA",null,{"v":0.142779253731343,"d":"0.14"},{"v":0.174918116010855,"d":"0.17"},{"v":0.816263386477833,"d":"0.82"},{"v":-0.292893348262813,"d":"-0.29"},1,1,"down","no"]
["ENSG00000071909","MYO3B","ENST00000408978;ENST00000442690;ENST00000317935;ENST00000602629","GO:0005737(cytoplasm);GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0003774(motor activity);GO:0016459(myosin complex);GO:0003779(actin binding);GO:0005856(cytoskeleton);GO:0050896(response to stimulus);GO:0007601(visual perception);GO:0007605(sensory perception of sound);GO:0032426(stereocilium tip);GO:0090103(cochlea morphogenesis);GO:0090103(cochlea morphogenesis)","NA","NA","NA","myosin IIIB [Source:HGNC Symbol;Acc:HGNC:15576]",{"v":0.0483727081107334,"d":"0.05"},{"v":0.053730144244779,"d":"0.05"},{"v":0.900289935764202,"d":"0.90"},{"v":-0.151538402858831,"d":"-0.15"},1,1,"down","no"]
["MSTRG.15470","FTH1P8","ENST00000498161","NA","NA","NA","NA","ferritin heavy chain 1 pseudogene 8 [Source:HGNC Symbol;Acc:HGNC:3995]",{"v":6.465279,"d":"6.47"},0,"inf","inf",1,1,"up","no"]
["ENSG00000228470","AL929236.1","ENST00000443622","NA","NA","NA","NA",null,0,{"v":0.031231,"d":"0.03"},"-inf","-inf",1,1,"down","no"]
["ENSG00000196081","ZNF724","ENST00000418100;ENST00000597037","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0005622(intracellular);GO:0005622(intracellular)","NA","NA","NA","zinc finger protein 724 [Source:HGNC Symbol;Acc:HGNC:32460]",{"v":0.0418152763395545,"d":"0.04"},{"v":0.0211534762191451,"d":"0.02"},{"v":1.97675672340366,"d":"1.98"},{"v":0.983135331595625,"d":"0.98"},1,1,"up","no"]
["ENSG00000183160","TMEM119","ENST00000392806","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005886(plasma membrane);GO:0030154(cell differentiation);GO:0007283(spermatogenesis);GO:0001503(ossification);GO:0003674(molecular_function);GO:0008150(biological_process);GO:0005575(cellular_component);GO:0031214(biomineral tissue development);GO:0030501(positive regulation of bone mineralization);GO:0048515(spermatid differentiation);GO:0033690(positive regulation of osteoblast proliferation);GO:0045669(positive regulation of osteoblast differentiation);GO:0001649(osteoblast differentiation);GO:1903012(positive regulation of bone development)","NA","NA","NA","transmembrane protein 119 [Source:HGNC Symbol;Acc:HGNC:27884]",{"v":0.0498609197240514,"d":"0.05"},{"v":0.0479280758858576,"d":"0.05"},{"v":1.04032800821792,"d":"1.04"},{"v":0.0570384718477906,"d":"0.06"},1,1,"up","no"]
["ENSG00000260540","ABHD17AP8","ENST00000569698","NA","NA","NA","NA","abhydrolase domain containing 17A pseudogene 8 [Source:HGNC Symbol;Acc:HGNC:38509]",0,0,1,0,1,1,"no","no"]
["ENSG00000114757","PEX5L","ENST00000467460;ENST00000463761","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005829(cytosol);GO:0043235(receptor complex);GO:0005778(peroxisomal membrane);GO:0031267(small GTPase binding);GO:0000268(peroxisome targeting sequence binding);GO:0043949(regulation of cAMP-mediated signaling);GO:0005052(peroxisome matrix targeting signal-1 binding);GO:0016560(protein import into peroxisome matrix, docking);GO:0016560(protein import into peroxisome matrix, docking)","04146(Peroxisome);04146(Peroxisome)","K13342","NA","peroxisomal biogenesis factor 5 like [Source:HGNC Symbol;Acc:HGNC:30024]",{"v":0.00518958753419304,"d":"0.01"},0,"inf","inf",1,1,"up","no"]
["MSTRG.3208","AC078950.1","ENST00000542062","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["MSTRG.11229","PRR23B","ENST00000329447","NA","NA","NA","NA","proline rich 23B [Source:HGNC Symbol;Acc:HGNC:33764]",0,0,1,0,1,1,"no","no"]
["ENSG00000109705","NKX3-2","ENST00000382438","GO:0005634(nucleus);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0043565(sequence-specific DNA binding);GO:0006366(transcription from RNA polymerase II promoter);GO:0001501(skeletal system development);GO:0032331(negative regulation of chondrocyte differentiation);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:0001078(transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0007368(determination of left/right symmetry);GO:0031016(pancreas development);GO:0042474(middle ear morphogenesis);GO:0043066(negative regulation of apoptotic process);GO:0048513(animal organ development);GO:0048536(spleen development);GO:0048645(animal organ formation);GO:0048705(skeletal system morphogenesis);GO:0048706(embryonic skeletal system development);GO:0055123(digestive system development);GO:0060576(intestinal epithelial cell development)","NA","NA","NA","NK3 homeobox 2 [Source:HGNC Symbol;Acc:HGNC:951]",0,0,1,0,1,1,"no","no"]
["ENSG00000242600","MBL1P","ENST00000480805","NA","NA","NA","NA","mannose binding lectin 1, pseudogene [Source:HGNC Symbol;Acc:HGNC:6921]",0,0,1,0,1,1,"no","no"]
["MSTRG.9566","UBOX5-AS1","ENST00000454019;ENST00000446537","NA","NA","NA","NA","UBOX5 antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:44111]",{"v":0.0175504607794771,"d":"0.02"},{"v":0.0170262101628022,"d":"0.02"},{"v":1.03079079910691,"d":"1.03"},{"v":0.0437515647955483,"d":"0.04"},1,1,"up","no"]
["ENSG00000184774","MGAT4EP","ENST00000549576","NA","NA","NA","NA","MGAT4 family member E, pseudogene [Source:HGNC Symbol;Acc:HGNC:49418]",0,0,1,0,1,1,"no","no"]
["ENSG00000185518","SV2B","ENST00000394232","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005215(transporter activity);GO:0055085(transmembrane transport);GO:0005515(protein binding);GO:0030054(cell junction);GO:0045202(synapse);GO:0031410(cytoplasmic vesicle);GO:0022857(transmembrane transporter activity);GO:0005886(plasma membrane);GO:0001669(acrosomal vesicle);GO:0030672(synaptic vesicle membrane);GO:0006836(neurotransmitter transport);GO:0008021(synaptic vesicle)","04512(ECM-receptor interaction)","K06258","NA","synaptic vesicle glycoprotein 2B [Source:HGNC Symbol;Acc:HGNC:16874]",0,{"v":0.0122054828167657,"d":"0.01"},"-inf","-inf",1,1,"down","no"]
["ENSG00000166813","KIF7","ENST00000394412","GO:0005737(cytoplasm);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0003777(microtubule motor activity);GO:0005856(cytoskeleton);GO:0042995(cell projection);GO:0008017(microtubule binding);GO:0007018(microtubule-based movement);GO:0005515(protein binding);GO:0005929(cilium);GO:0097542(ciliary tip);GO:0036064(ciliary basal body);GO:0005871(kinesin complex);GO:0008574(ATP-dependent microtubule motor activity, plus-end-directed);GO:0045879(negative regulation of smoothened signaling pathway);GO:0045880(positive regulation of smoothened signaling pathway);GO:0003774(motor activity)","04340(Hedgehog signaling pathway);05200(Pathways in cancer);05217(Basal cell carcinoma)","K18806","NA","kinesin family member 7 [Source:HGNC Symbol;Acc:HGNC:30497]",{"v":0.0318651901619676,"d":"0.03"},{"v":0.035610824235153,"d":"0.04"},{"v":0.894817540631707,"d":"0.89"},{"v":-0.160334557830576,"d":"-0.16"},1,1,"down","no"]
["MSTRG.7077","AC004686.1","ENST00000605113","NA","NA","NA","NA",null,{"v":0.29588,"d":"0.30"},{"v":0.094594,"d":"0.09"},{"v":3.12789394676195,"d":"3.13"},{"v":1.64519159797954,"d":"1.65"},1,1,"up","no"]
["ENSG00000126787","DLGAP5","ENST00000247191;ENST00000557645;ENST00000395425","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005739(mitochondrion);GO:0004721(phosphoprotein phosphatase activity);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0007049(cell cycle);GO:0005815(microtubule organizing center);GO:0006470(protein dephosphorylation);GO:0005819(spindle);GO:0023052(signaling);GO:0008283(cell proliferation);GO:0006461(protein complex assembly);GO:0031616(spindle pole centrosome);GO:0045842(positive regulation of mitotic metaphase/anaphase transition);GO:0007079(mitotic chromosome movement towards spindle pole);GO:0007079(mitotic chromosome movement towards spindle pole)","NA","NA","NA","DLG associated protein 5 [Source:HGNC Symbol;Acc:HGNC:16864]",{"v":0.24458178238342,"d":"0.24"},{"v":0.0552838551949823,"d":"0.06"},{"v":4.42410865741539,"d":"4.42"},{"v":2.14538681902409,"d":"2.15"},1,1,"up","no"]
["ENSG00000248445","SEMA6A-AS1","ENST00000508640;ENST00000508424;ENST00000514214","NA","NA","NA","NA","SEMA6A antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:51110]",{"v":0.0388188490632732,"d":"0.04"},{"v":0.0325610922587487,"d":"0.03"},{"v":1.19218510100327,"d":"1.19"},{"v":0.253608248860058,"d":"0.25"},1,1,"up","no"]
["ENSG00000183615","FAM167B","ENST00000373582","NA","NA","NA","NA","family with sequence similarity 167 member B [Source:HGNC Symbol;Acc:HGNC:28133]",{"v":0.168662,"d":"0.17"},{"v":0.033459,"d":"0.03"},{"v":5.04085597298186,"d":"5.04"},{"v":2.33366873434465,"d":"2.33"},1,1,"up","no"]
["ENSG00000141519","CCDC40","ENST00000397545;ENST00000574799;ENST00000374877;ENST00000571028;ENST00000574099","GO:0003674(molecular_function);GO:0005737(cytoplasm);GO:0042995(cell projection);GO:0005929(cilium);GO:0001947(heart looping);GO:0030324(lung development);GO:0035469(determination of pancreatic left/right asymmetry);GO:0071907(determination of digestive tract left/right asymmetry);GO:0071910(determination of liver left/right asymmetry);GO:0060287(epithelial cilium movement involved in determination of left/right asymmetry);GO:0003351(epithelial cilium movement);GO:0070286(axonemal dynein complex assembly);GO:0003341(cilium movement);GO:0003356(regulation of cilium beat frequency);GO:0030317(flagellated sperm motility);GO:0035082(axoneme assembly);GO:0036159(inner dynein arm assembly);GO:0044458(motile cilium assembly);GO:0005930(axoneme);GO:0005930(axoneme)","NA","NA","NA","coiled-coil domain containing 40 [Source:HGNC Symbol;Acc:HGNC:26090]",{"v":0.00397121283003714,"d":"0.00"},{"v":0.00510917458086538,"d":"0.01"},{"v":0.777270920612093,"d":"0.78"},{"v":-0.363510551983444,"d":"-0.36"},1,1,"down","no"]
["ENSG00000179073","TAAR3P","ENST00000481759;ENST00000466706","NA","NA","NA","NA","trace amine associated receptor 3, pseudogene [Source:HGNC Symbol;Acc:HGNC:4513]",0,0,1,0,1,1,"no","no"]
["ENSG00000165588","OTX2","ENST00000339475","GO:0005634(nucleus);GO:0006355(regulation of transcription, DNA-templated);GO:0006366(transcription from RNA polymerase II promoter);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0007275(multicellular organism development);GO:0043565(sequence-specific DNA binding);GO:0045893(positive regulation of transcription, DNA-templated);GO:0005515(protein binding);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0030426(growth cone);GO:0043234(protein complex);GO:0008190(eukaryotic initiation factor 4E binding);GO:0007411(axon guidance);GO:0001077(transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0006461(protein complex assembly);GO:0071542(dopaminergic neuron differentiation);GO:0030901(midbrain development);GO:0008589(regulation of smoothened signaling pathway);GO:0040036(regulation of fibroblast growth factor receptor signaling pathway);GO:0030900(forebrain development);GO:0040019(positive regulation of embryonic development);GO:0090009(primitive streak formation);GO:2000543(positive regulation of gastrulation)","NA","NA","NA","orthodenticle homeobox 2 [Source:HGNC Symbol;Acc:HGNC:8522]",0,0,1,0,1,1,"no","no"]
["ENSG00000164729","SLC35G3","ENST00000297307","GO:0016020(membrane);GO:0016021(integral component of membrane)","NA","NA","NA","solute carrier family 35 member G3 [Source:HGNC Symbol;Acc:HGNC:26848]",0,0,1,0,1,1,"no","no"]
["MSTRG.8118","AC011455.1","ENST00000593830","NA","NA","NA","NA",null,{"v":0.126667,"d":"0.13"},{"v":0.04633,"d":"0.05"},{"v":2.73401683574358,"d":"2.73"},{"v":1.45102212691215,"d":"1.45"},1,1,"up","no"]
["MSTRG.1259","PACERR","ENST00000608917","NA","NA","NA","NA","PTGS2 antisense NFKB1 complex-mediated expression regulator RNA [Source:HGNC Symbol;Acc:HGNC:50552]",0,0,1,0,1,1,"no","no"]
["ENSG00000265415","AC099850.3","ENST00000577678","NA","NA","NA","NA",null,{"v":0.40302,"d":"0.40"},{"v":0.331522,"d":"0.33"},{"v":1.21566592865632,"d":"1.22"},{"v":0.281746823117229,"d":"0.28"},1,1,"up","no"]
["ENSG00000273111","LYPD4","ENST00000609812","GO:0016020(membrane);GO:0005886(plasma membrane);GO:0031225(anchored component of membrane);GO:0005576(extracellular region);GO:0006501(C-terminal protein lipidation)","NA","NA","NA","LY6/PLAUR domain containing 4 [Source:HGNC Symbol;Acc:HGNC:28659]",{"v":0.000650378752886836,"d":"0.00"},0,"inf","inf",1,1,"up","no"]
["MSTRG.6843","WNK4","ENST00000246914","GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0006811(ion transport);GO:0005515(protein binding);GO:0065009(regulation of molecular function);GO:0030054(cell junction);GO:0035556(intracellular signal transduction);GO:0005923(bicellular tight junction);GO:0005829(cytosol);GO:0070294(renal sodium ion absorption);GO:0016020(membrane);GO:0019869(chloride channel inhibitor activity);GO:0010766(negative regulation of sodium ion transport);GO:0006821(chloride transport);GO:0008104(protein localization);GO:0050794(regulation of cellular process);GO:0050801(ion homeostasis);GO:0072156(distal tubule morphogenesis);GO:0090188(negative regulation of pancreatic juice secretion);GO:0005737(cytoplasm)","NA","NA","NA","WNK lysine deficient protein kinase 4 [Source:HGNC Symbol;Acc:HGNC:14544]",0,0,1,0,1,1,"no","no"]
["ENSG00000249451","AC021491.1","ENST00000502300","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000138400","MDH1B","ENST00000374412","GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0006099(tricarboxylic acid cycle);GO:0003824(catalytic activity);GO:0005975(carbohydrate metabolic process);GO:0016616(oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor);GO:0016615(malate dehydrogenase activity);GO:0006108(malate metabolic process);GO:0005737(cytoplasm);GO:0030060(L-malate dehydrogenase activity);GO:0006107(oxaloacetate metabolic process);GO:0006734(NADH metabolic process)","NA","NA","NA","malate dehydrogenase 1B [Source:HGNC Symbol;Acc:HGNC:17836]",0,0,1,0,1,1,"no","no"]
["ENSG00000277770","AC137803.1","ENST00000611162","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["MSTRG.15029","AL158151.2","ENST00000434250","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000124019","FAM124B","ENST00000243806;ENST00000389874","GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005739(mitochondrion);GO:0005515(protein binding);GO:0005515(protein binding)","NA","NA","NA","family with sequence similarity 124 member B [Source:HGNC Symbol;Acc:HGNC:26224]",{"v":0.164667354419655,"d":"0.16"},{"v":0.242327735103078,"d":"0.24"},{"v":0.679523350266164,"d":"0.68"},{"v":-0.557404968126635,"d":"-0.56"},1,1,"down","no"]
["ENSG00000163092","XIRP2","ENST00000409195","GO:0003779(actin binding);GO:0030036(actin cytoskeleton organization);GO:0030054(cell junction);GO:0005925(focal adhesion);GO:0007507(heart development);GO:0008150(biological_process);GO:0001725(stress fiber);GO:0031941(filamentous actin);GO:0051393(alpha-actinin binding);GO:0003281(ventricular septum development);GO:0045216(cell-cell junction organization);GO:0055008(cardiac muscle tissue morphogenesis);GO:0030018(Z disc)","NA","NA","NA","xin actin binding repeat containing 2 [Source:HGNC Symbol;Acc:HGNC:14303]",{"v":4.07650410559435E-3,"d":"0.00"},{"v":0.0112762853963625,"d":"0.01"},{"v":0.361511256792893,"d":"0.36"},{"v":-1.46788752415236,"d":"-1.47"},1,1,"down","no"]
["ENSG00000251423","AC016576.1","ENST00000637153","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000231831","MTHFD1P1","ENST00000413059","NA","NA","NA","NA","methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 pseudogene 1 [Source:HGNC Symbol;Acc:HGNC:7433]",0,0,1,0,1,1,"no","no"]
["ENSG00000259158","ADAM20P1","ENST00000320746","NA","NA","NA","NA","ADAM metallopeptidase domain 20 pseudogene 1 [Source:HGNC Symbol;Acc:HGNC:20102]",{"v":0.0175078648648649,"d":"0.02"},0,"inf","inf",1,1,"up","no"]
["ENSG00000280216","AL022326.2","ENST00000623458","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["MSTRG.1504","LINC01341","ENST00000421003;ENST00000419361;ENST00000426089;ENST00000505748","NA","NA","NA","NA","long intergenic non-protein coding RNA 1341 [Source:HGNC Symbol;Acc:HGNC:49457]",{"v":0.00397374497991968,"d":"0.00"},{"v":0.0651962361947791,"d":"0.07"},{"v":0.060950527390075,"d":"0.06"},{"v":-4.03621748558627,"d":"-4.04"},1,1,"down","no"]
["ENSG00000214894","LINC00243","ENST00000419357;ENST00000399196","NA","NA","NA","NA","long intergenic non-protein coding RNA 243 [Source:HGNC Symbol;Acc:HGNC:30956]",{"v":0.708758542607093,"d":"0.71"},{"v":0.269501483187471,"d":"0.27"},{"v":2.62988735432697,"d":"2.63"},{"v":1.39500100604447,"d":"1.40"},1,1,"up","no"]
["ENSG00000229743","LINC01159","ENST00000434764;ENST00000433433","NA","NA","NA","NA","long intergenic non-protein coding RNA 1159 [Source:HGNC Symbol;Acc:HGNC:49514]",0,0,1,0,1,1,"no","no"]
["ENSG00000268499","AC011479.2","ENST00000598146","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000224089","CT47A10","ENST00000430448","NA","NA","NA","NA","cancer/testis antigen family 47, member A10 [Source:HGNC Symbol;Acc:HGNC:33291]",0,0,1,0,1,1,"no","no"]
["ENSG00000126010","GRPR","ENST00000380289","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0004930(G-protein coupled receptor activity);GO:0007186(G-protein coupled receptor signaling pathway);GO:0005886(plasma membrane);GO:0004871(signal transducer activity);GO:0007165(signal transduction);GO:0007218(neuropeptide signaling pathway);GO:0005887(integral component of plasma membrane);GO:0008283(cell proliferation);GO:0035176(social behavior);GO:0007200(phospholipase C-activating G-protein coupled receptor signaling pathway);GO:0008528(G-protein coupled peptide receptor activity);GO:0008188(neuropeptide receptor activity);GO:0036343(psychomotor behavior);GO:0042127(regulation of cell proliferation);GO:0043207(response to external biotic stimulus);GO:0061744(motor behavior)","04020(Calcium signaling pathway);04080(Neuroactive ligand-receptor interaction)","K04169","NA","gastrin releasing peptide receptor [Source:HGNC Symbol;Acc:HGNC:4609]",{"v":0.068844,"d":"0.07"},{"v":0.013191,"d":"0.01"},{"v":5.21901296338413,"d":"5.22"},{"v":2.38377698543932,"d":"2.38"},1,1,"up","no"]
["ENSG00000261873","AC006269.1","ENST00000636752","GO:0016020(membrane);GO:0016021(integral component of membrane)","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["MSTRG.11387","CAMK2N2","ENST00000296238","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005813(centrosome);GO:0004860(protein kinase inhibitor activity);GO:0006469(negative regulation of protein kinase activity);GO:0008427(calcium-dependent protein kinase inhibitor activity);GO:0019901(protein kinase binding)","NA","NA","NA","calcium/calmodulin dependent protein kinase II inhibitor 2 [Source:HGNC Symbol;Acc:HGNC:24197]",{"v":0.039001,"d":"0.04"},{"v":0.074731,"d":"0.07"},{"v":0.521885161445719,"d":"0.52"},{"v":-0.938195711923007,"d":"-0.94"},1,1,"down","no"]
["MSTRG.6336","C17orf107","ENST00000381365;ENST00000521575","NA","NA","NA","NA","chromosome 17 open reading frame 107 [Source:HGNC Symbol;Acc:HGNC:37238]",{"v":0.257509174589202,"d":"0.26"},{"v":0.0478023987676056,"d":"0.05"},{"v":5.38695089008188,"d":"5.39"},{"v":2.42946891296645,"d":"2.43"},1,1,"up","no"]
["MSTRG.12788","AL645939.3","ENST00000435408","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000130413","STK33","ENST00000486305;ENST00000526517;ENST00000447869","GO:0005737(cytoplasm);GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0048471(perinuclear region of cytoplasm);GO:0005622(intracellular);GO:0035556(intracellular signal transduction);GO:0018105(peptidyl-serine phosphorylation);GO:0046777(protein autophosphorylation);GO:0018107(peptidyl-threonine phosphorylation);GO:0018107(peptidyl-threonine phosphorylation)","NA","NA","NA","serine/threonine kinase 33 [Source:HGNC Symbol;Acc:HGNC:14568]",{"v":0.035964891301487,"d":"0.04"},{"v":0.020047428345835,"d":"0.02"},{"v":1.79399026553742,"d":"1.79"},{"v":0.843172061996869,"d":"0.84"},1,1,"up","no"]
["MSTRG.10495","EP300-AS1","ENST00000420537","NA","NA","NA","NA","EP300 antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:50504]",{"v":0.04851,"d":"0.05"},{"v":0.044929,"d":"0.04"},{"v":1.07970353223976,"d":"1.08"},{"v":0.110635227867152,"d":"0.11"},1,1,"up","no"]
["MSTRG.625","WDR78","ENST00000488333;ENST00000491297;ENST00000532629;ENST00000371026;ENST00000531980","GO:0008574(ATP-dependent microtubule motor activity, plus-end-directed);GO:0045503(dynein light chain binding);GO:0045504(dynein heavy chain binding);GO:0003341(cilium movement);GO:0005858(axonemal dynein complex);GO:0002244(hematopoietic progenitor cell differentiation);GO:0002244(hematopoietic progenitor cell differentiation)","NA","NA","NA","WD repeat domain 78 [Source:HGNC Symbol;Acc:HGNC:26252]",{"v":0.0443047483591885,"d":"0.04"},{"v":0.039202375,"d":"0.04"},{"v":1.1301547000453,"d":"1.13"},{"v":0.176520267961052,"d":"0.18"},1,1,"up","no"]
["MSTRG.14939","AL513122.1","ENST00000455437","NA","NA","NA","NA",null,0,{"v":0.025957,"d":"0.03"},"-inf","-inf",1,1,"down","no"]
["ENSG00000144331","ZNF385B","ENST00000410066","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0001650(fibrillar center);GO:0006915(apoptotic process);GO:0003723(RNA binding);GO:0002039(p53 binding);GO:0072332(intrinsic apoptotic signaling pathway by p53 class mediator)","NA","NA","NA","zinc finger protein 385B [Source:HGNC Symbol;Acc:HGNC:26332]",0,{"v":4.79205875706215E-3,"d":"0.00"},"-inf","-inf",1,1,"down","no"]
["ENSG00000159374","M1AP","ENST00000290536;ENST00000464686","GO:0005737(cytoplasm);GO:0016021(integral component of membrane);GO:0005515(protein binding);GO:0030154(cell differentiation);GO:0007283(spermatogenesis);GO:0042802(identical protein binding);GO:0003674(molecular_function);GO:0007127(meiosis I);GO:0006396(RNA processing);GO:0031497(chromatin assembly);GO:0007292(female gamete generation);GO:0051308(male meiosis chromosome separation);GO:0051308(male meiosis chromosome separation)","NA","NA","NA","meiosis 1 associated protein [Source:HGNC Symbol;Acc:HGNC:25183]",{"v":0.259746258333333,"d":"0.26"},{"v":0.123054688666667,"d":"0.12"},{"v":2.11081967820778,"d":"2.11"},{"v":1.0778033382933,"d":"1.08"},1,1,"up","no"]
["ENSG00000251260","WDFY3-AS1","ENST00000510449","NA","NA","NA","NA","WDFY3 antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:40935]",0,0,1,0,1,1,"no","no"]
["ENSG00000136698","CFC1","ENST00000615342","GO:0016020(membrane);GO:0005886(plasma membrane);GO:0005576(extracellular region);GO:0007275(multicellular organism development);GO:0031225(anchored component of membrane);GO:0003674(molecular_function);GO:0005575(cellular_component);GO:0007368(determination of left/right symmetry);GO:0007369(gastrulation);GO:0038100(nodal binding);GO:0038092(nodal signaling pathway)","NA","NA","NA","cripto, FRL-1, cryptic family 1 [Source:HGNC Symbol;Acc:HGNC:18292]",0,0,1,0,1,1,"no","no"]
["ENSG00000004776","HSPB6","ENST00000004982","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0042803(protein homodimerization activity);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0005212(structural constituent of eye lens);GO:0051082(unfolded protein binding);GO:0051087(chaperone binding);GO:0006937(regulation of muscle contraction);GO:0010667(negative regulation of cardiac muscle cell apoptotic process);GO:0045766(positive regulation of angiogenesis);GO:0061077(chaperone-mediated protein folding)","NA","NA","NA","heat shock protein family B (small) member 6 [Source:HGNC Symbol;Acc:HGNC:26511]",0,0,1,0,1,1,"no","no"]
["MSTRG.11032","AC012557.3","ENST00000626439","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000104967","NOVA2","ENST00000263257","GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0005634(nucleus);GO:0000398(mRNA splicing, via spliceosome);GO:0051252(regulation of RNA metabolic process)","NA","NA","NA","NOVA alternative splicing regulator 2 [Source:HGNC Symbol;Acc:HGNC:7887]",0,0,1,0,1,1,"no","no"]
["ENSG00000169800","RBMY1F","ENST00000303766","GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0006397(mRNA processing);GO:0008380(RNA splicing);GO:0005634(nucleus);GO:0005515(protein binding);GO:0007283(spermatogenesis);GO:0042802(identical protein binding);GO:0005575(cellular_component)","NA","NA","NA","RNA binding motif protein, Y-linked, family 1, member F [Source:HGNC Symbol;Acc:HGNC:23974]",0,0,1,0,1,1,"no","no"]
["ENSG00000188716","DUPD1","ENST00000338487","GO:0005737(cytoplasm);GO:0016787(hydrolase activity);GO:0004725(protein tyrosine phosphatase activity);GO:0008138(protein tyrosine/serine/threonine phosphatase activity);GO:0016791(phosphatase activity);GO:0006470(protein dephosphorylation);GO:0016311(dephosphorylation);GO:0035335(peptidyl-tyrosine dephosphorylation);GO:0004721(phosphoprotein phosphatase activity)","NA","NA","NA","dual specificity phosphatase and pro isomerase domain containing 1 [Source:HGNC Symbol;Acc:HGNC:23481]",{"v":0.059602,"d":"0.06"},{"v":0.018048,"d":"0.02"},{"v":3.30241578014184,"d":"3.30"},{"v":1.72352176961108,"d":"1.72"},1,1,"up","no"]
["ENSG00000204172","AGAP9","ENST00000452145","GO:0046872(metal ion binding);GO:0043547(positive regulation of GTPase activity);GO:0005096(GTPase activator activity)","NA","NA","NA","ArfGAP with GTPase domain, ankyrin repeat and PH domain 9 [Source:HGNC Symbol;Acc:HGNC:23463]",{"v":0.227698,"d":"0.23"},{"v":0.452717,"d":"0.45"},{"v":0.502958802077236,"d":"0.50"},{"v":-0.991487862795003,"d":"-0.99"},1,1,"down","no"]
["ENSG00000255251","PRR23D1","ENST00000533250","NA","NA","NA","NA","proline rich 23 domain containing 1 [Source:HGNC Symbol;Acc:HGNC:49420]",0,{"v":0.016034,"d":"0.02"},"-inf","-inf",1,1,"down","no"]
["ENSG00000278616","BEND3P3","ENST00000611030","NA","NA","NA","NA","BEN domain containing 3 pseudogene 3 [Source:HGNC Symbol;Acc:HGNC:45016]",{"v":0.141796,"d":"0.14"},{"v":0.150248,"d":"0.15"},{"v":0.943746339385549,"d":"0.94"},{"v":-0.0835289514939994,"d":"-0.08"},1,1,"down","no"]
["ENSG00000103647","CORO2B","ENST00000543950;ENST00000540068","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0051015(actin filament binding);GO:0003779(actin binding);GO:0030036(actin cytoskeleton organization);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0015629(actin cytoskeleton);GO:0015629(actin cytoskeleton)","NA","NA","NA","coronin 2B [Source:HGNC Symbol;Acc:HGNC:2256]",{"v":0.363136328164082,"d":"0.36"},{"v":0.144490579289645,"d":"0.14"},{"v":2.5132180239664,"d":"2.51"},{"v":1.32953583176426,"d":"1.33"},1,1,"up","no"]
["ENSG00000250483","PPM1AP1","ENST00000502740","NA","NA","NA","NA","protein phosphatase, Mg2+/Mn2+ dependent 1A pseudogene 1 [Source:HGNC Symbol;Acc:HGNC:30175]",0,0,1,0,1,1,"no","no"]
["MSTRG.984","S100A1","ENST00000368698;ENST00000469893","GO:0046872(metal ion binding);GO:0005509(calcium ion binding);GO:0005515(protein binding);GO:0042802(identical protein binding);GO:0008016(regulation of heart contraction);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0042803(protein homodimerization activity);GO:0005576(extracellular region);GO:0048306(calcium-dependent protein binding);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:1901387(positive regulation of voltage-gated calcium channel activity);GO:0030018(Z disc);GO:0031430(M band);GO:0031672(A band);GO:0031674(I band);GO:0043005(neuron projection);GO:0016529(sarcoplasmic reticulum);GO:0043234(protein complex);GO:0021762(substantia nigra development);GO:0002224(toll-like receptor signaling pathway);GO:0035556(intracellular signal transduction);GO:0044548(S100 protein binding);GO:0051117(ATPase binding);GO:0051117(ATPase binding)","NA","NA","NA","S100 calcium binding protein A1 [Source:HGNC Symbol;Acc:HGNC:10486]",{"v":0.0175312894389439,"d":"0.02"},{"v":0.0247828590759076,"d":"0.02"},{"v":0.707395760321567,"d":"0.71"},{"v":-0.499410522415367,"d":"-0.50"},1,1,"down","no"]
["MSTRG.4640","SNHG10","ENST00000553559;ENST00000500370;ENST00000554169","NA","NA","NA","NA","small nucleolar RNA host gene 10 [Source:HGNC Symbol;Acc:HGNC:27510]",{"v":0.133091276092545,"d":"0.13"},{"v":0.121543858097686,"d":"0.12"},{"v":1.09500618275239,"d":"1.10"},{"v":0.130939015763459,"d":"0.13"},1,1,"up","no"]
["ENSG00000134533","RERG","ENST00000537647;ENST00000256953","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005525(GTP binding);GO:0016020(membrane);GO:0000166(nucleotide binding);GO:0007165(signal transduction);GO:0003924(GTPase activity);GO:0005829(cytosol);GO:0008285(negative regulation of cell proliferation);GO:0030331(estrogen receptor binding);GO:0019003(GDP binding);GO:0030308(negative regulation of cell growth);GO:0009725(response to hormone);GO:0007264(small GTPase mediated signal transduction);GO:0007264(small GTPase mediated signal transduction)","NA","NA","NA","RAS like estrogen regulated growth inhibitor [Source:HGNC Symbol;Acc:HGNC:15980]",0,0,1,0,1,1,"no","no"]
["MSTRG.4065","FARP1-AS1","ENST00000432229","NA","NA","NA","NA","FARP1 antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:40229]",0,0,1,0,1,1,"no","no"]
["MSTRG.252","NCMAP","ENST00000486262","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005886(plasma membrane);GO:0005887(integral component of plasma membrane);GO:0019911(structural constituent of myelin sheath);GO:0033270(paranode region of axon);GO:0031643(positive regulation of myelination);GO:0032290(peripheral nervous system myelin formation);GO:0043220(Schmidt-Lanterman incisure)","NA","NA","NA","non-compact myelin associated protein [Source:HGNC Symbol;Acc:HGNC:29332]",0,0,1,0,1,1,"no","no"]
["MSTRG.7757","AC010336.4","ENST00000595655","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000243517","AC024940.2","ENST00000495623","NA","NA","NA","NA",null,{"v":0.427833,"d":"0.43"},{"v":0.948806,"d":"0.95"},{"v":0.450917258111774,"d":"0.45"},{"v":-1.14906536709025,"d":"-1.15"},1,1,"down","no"]
["ENSG00000151379","MSGN1","ENST00000281047","GO:0005634(nucleus);GO:0046983(protein dimerization activity);GO:0006366(transcription from RNA polymerase II promoter);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0007275(multicellular organism development);GO:0030154(cell differentiation);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:0001077(transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0001228(transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding);GO:0003682(chromatin binding);GO:0001707(mesoderm formation);GO:0001756(somitogenesis);GO:0007379(segment specification);GO:0009880(embryonic pattern specification)","NA","NA","NA","mesogenin 1 [Source:HGNC Symbol;Acc:HGNC:14907]",0,0,1,0,1,1,"no","no"]
["ENSG00000279948","AC008895.1","ENST00000624074","NA","NA","NA","NA",null,{"v":0.060644,"d":"0.06"},{"v":0.038755,"d":"0.04"},{"v":1.5648045413495,"d":"1.56"},{"v":0.645982462374219,"d":"0.65"},1,1,"up","no"]
["ENSG00000215217","C5orf49","ENST00000399810","NA","NA","NA","NA","chromosome 5 open reading frame 49 [Source:HGNC Symbol;Acc:HGNC:27028]",0,0,1,0,1,1,"no","no"]
["ENSG00000261792","DNM1P28","ENST00000565702","NA","NA","NA","NA","dynamin 1 pseudogene 28 [Source:HGNC Symbol;Acc:HGNC:35175]",0,0,1,0,1,1,"no","no"]
["MSTRG.14726","AL354989.1","ENST00000448245","NA","NA","NA","NA",null,{"v":0.291313,"d":"0.29"},{"v":0.339444,"d":"0.34"},{"v":0.858206360990325,"d":"0.86"},{"v":-0.220603500565003,"d":"-0.22"},1,1,"down","no"]
["MSTRG.1907","AL138921.2","ENST00000443919","NA","NA","NA","NA",null,{"v":0.242671,"d":"0.24"},{"v":0.048779,"d":"0.05"},{"v":4.97490723467066,"d":"4.97"},{"v":2.31466962448476,"d":"2.31"},1,1,"up","no"]
["ENSG00000241095","CYP51A1P1","ENST00000492267","NA","NA","NA","NA","cytochrome P450 family 51 subfamily A member 1 pseudogene 1 [Source:HGNC Symbol;Acc:HGNC:20245]",0,0,1,0,1,1,"no","no"]
["ENSG00000243480","AMY2A","ENST00000414303;ENST00000622339","GO:0046872(metal ion binding);GO:0016787(hydrolase activity);GO:0003824(catalytic activity);GO:0005975(carbohydrate metabolic process);GO:0008152(metabolic process);GO:0005576(extracellular region);GO:0016798(hydrolase activity, acting on glycosyl bonds);GO:0005615(extracellular space);GO:0043169(cation binding);GO:0005509(calcium ion binding);GO:0070062(extracellular exosome);GO:0044245(polysaccharide digestion);GO:0004556(alpha-amylase activity);GO:0031404(chloride ion binding);GO:0016052(carbohydrate catabolic process);GO:0016052(carbohydrate catabolic process)","00500(Starch and sucrose metabolism);04972(Pancreatic secretion);04973(Carbohydrate digestion and absorption);04973(Carbohydrate digestion and absorption)","K01176","EC:3.2.1.1","amylase, alpha 2A (pancreatic) [Source:HGNC Symbol;Acc:HGNC:477]",{"v":0.0894757049525817,"d":"0.09"},{"v":0.0580956733403583,"d":"0.06"},{"v":1.54014403841024,"d":"1.54"},{"v":0.623065281947891,"d":"0.62"},1,1,"up","no"]
["MSTRG.6979","AC018521.2","ENST00000580372;ENST00000582142","NA","NA","NA","NA",null,{"v":0.0959130284629981,"d":"0.10"},0,"inf","inf",1,1,"up","no"]
["ENSG00000261537","AC027279.2","ENST00000561938","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000137077","CCL21","ENST00000378792","GO:0051897(positive regulation of protein kinase B signaling);GO:0070374(positive regulation of ERK1 and ERK2 cascade);GO:0005623(cell);GO:0005576(extracellular region);GO:0006955(immune response);GO:0007186(G-protein coupled receptor signaling pathway);GO:0005125(cytokine activity);GO:0005615(extracellular space);GO:0008009(chemokine activity);GO:0006935(chemotaxis);GO:0006954(inflammatory response);GO:0060326(cell chemotaxis);GO:0048020(CCR chemokine receptor binding);GO:0002548(monocyte chemotaxis);GO:0048247(lymphocyte chemotaxis);GO:0070098(chemokine-mediated signaling pathway);GO:0071346(cellular response to interferon-gamma);GO:0071347(cellular response to interleukin-1);GO:0071356(cellular response to tumor necrosis factor);GO:0005515(protein binding);GO:0005578(proteinaceous extracellular matrix);GO:0007267(cell-cell signaling);GO:0030838(positive regulation of actin filament polymerization);GO:0051491(positive regulation of filopodium assembly);GO:0042379(chemokine receptor binding);GO:0046330(positive regulation of JNK cascade);GO:0031732(CCR7 chemokine receptor binding);GO:0001768(establishment of T cell polarity);GO:0001771(immunological synapse formation);GO:0001954(positive regulation of cell-matrix adhesion);GO:0002407(dendritic cell chemotaxis);GO:0002606(positive regulation of dendritic cell antigen processing and presentation);GO:0010560(positive regulation of glycoprotein biosynthetic process);GO:0031274(positive regulation of pseudopodium assembly);GO:0031295(T cell costimulation);GO:0031529(ruffle organization);GO:0033630(positive regulation of cell adhesion mediated by integrin);GO:0034695(response to prostaglandin E);GO:0035759(mesangial cell-matrix adhesion);GO:0043123(positive regulation of I-kappaB kinase/NF-kappaB signaling);GO:0043552(positive regulation of phosphatidylinositol 3-kinase activity);GO:0045860(positive regulation of protein kinase activity);GO:0048260(positive regulation of receptor-mediated endocytosis);GO:0048469(cell maturation);GO:0050921(positive regulation of chemotaxis);GO:0051209(release of sequestered calcium ion into cytosol);GO:0090023(positive regulation of neutrophil chemotaxis);GO:0090630(activation of GTPase activity);GO:0097026(dendritic cell dendrite assembly);GO:1903237(negative regulation of leukocyte tethering or rolling);GO:2000107(negative regulation of leukocyte apoptotic process);GO:2000147(positive regulation of cell motility);GO:2000406(positive regulation of T cell migration);GO:2000529(positive regulation of myeloid dendritic cell chemotaxis);GO:2000548(negative regulation of dendritic cell dendrite assembly)","04064(NF-kappa B signaling pathway);04060(Cytokine-cytokine receptor interaction);04062(Chemokine signaling pathway)","NA","NA","C-C motif chemokine ligand 21 [Source:HGNC Symbol;Acc:HGNC:10620]",0,0,1,0,1,1,"no","no"]
["ENSG00000261167","AC107027.3","ENST00000565095","NA","NA","NA","NA",null,0,{"v":0.116695,"d":"0.12"},"-inf","-inf",1,1,"down","no"]
["MSTRG.5842","ZNF771","ENST00000566625;ENST00000434417;ENST00000564550;ENST00000319296","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0005730(nucleolus);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0003677(DNA binding)","NA","NA","NA","zinc finger protein 771 [Source:HGNC Symbol;Acc:HGNC:29653]",{"v":0.0518288350186269,"d":"0.05"},{"v":0.0989808949795991,"d":"0.10"},{"v":0.523624635130944,"d":"0.52"},{"v":-0.933395121085534,"d":"-0.93"},1,1,"down","no"]
["MSTRG.11684","LINC02469","ENST00000506460","NA","NA","NA","NA","long intergenic non-protein coding RNA 2469 [Source:HGNC Symbol;Acc:HGNC:53408]",0,0,1,0,1,1,"no","no"]
["ENSG00000261745","AL512347.1","ENST00000566420","NA","NA","NA","NA",null,{"v":0.105606,"d":"0.11"},{"v":0.101177,"d":"0.10"},{"v":1.04377477094597,"d":"1.04"},{"v":0.0618104361465405,"d":"0.06"},1,1,"up","no"]
["MSTRG.7250","CYGB;AC015802.4","ENST00000590175;ENST00000592622;ENST00000293230;ENST00000589963;ENST00000591967;ENST00000607136;ENST00000589145","GO:0006810(transport);GO:0005737(cytoplasm);GO:0016607(nuclear speck);GO:0046872(metal ion binding);GO:0005506(iron ion binding);GO:0005515(protein binding);GO:0020037(heme binding);GO:0098869(cellular oxidant detoxification);GO:0004601(peroxidase activity);GO:0005344(oxygen transporter activity);GO:0019825(oxygen binding);GO:0015671(oxygen transport);GO:0004096(catalase activity);GO:0047888(fatty acid peroxidase activity);GO:0001666(response to hypoxia);GO:0006979(response to oxidative stress);GO:0010764(negative regulation of fibroblast migration);GO:0019395(fatty acid oxidation);GO:0032966(negative regulation of collagen biosynthetic process);GO:2000490(negative regulation of hepatic stellate cell activation);GO:0043005(neuron projection);GO:0043025(neuronal cell body);GO:0005829(cytosol);GO:0050999(regulation of nitric-oxide synthase activity);GO:0008941(nitric oxide dioxygenase activity);GO:0008941(nitric oxide dioxygenase activity)","NA","NA","NA","cytoglobin [Source:HGNC Symbol;Acc:HGNC:16505]",{"v":0.0465520024148756,"d":"0.05"},{"v":0.0597554445786042,"d":"0.06"},{"v":0.779042022750573,"d":"0.78"},{"v":-0.360226943264479,"d":"-0.36"},1,1,"down","no"]
["ENSG00000198678","AC089987.2","ENST00000328207","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000214049","UCA1","ENST00000397381","NA","NA","NA","NA","urothelial cancer associated 1 (non-protein coding) [Source:HGNC Symbol;Acc:HGNC:37126]",0,0,1,0,1,1,"no","no"]
["ENSG00000232850","PTGES2-AS1","ENST00000443493","NA","NA","NA","NA","PTGES2 antisense RNA 1 (head to head) [Source:NCBI gene;Acc:389791]",{"v":0.05059,"d":"0.05"},{"v":0.072542,"d":"0.07"},{"v":0.697389098729012,"d":"0.70"},{"v":-0.51996428215289,"d":"-0.52"},1,1,"down","no"]
["ENSG00000267667","AC005856.1","ENST00000585921","NA","NA","NA","NA",null,{"v":0.106347,"d":"0.11"},{"v":0.160434,"d":"0.16"},{"v":0.662870713190471,"d":"0.66"},{"v":-0.593200581453601,"d":"-0.59"},1,1,"down","no"]
["ENSG00000267978","MAGEA9B","ENST00000595065","GO:0005515(protein binding);GO:0003674(molecular_function);GO:0008150(biological_process);GO:0005575(cellular_component)","NA","NA","NA","MAGE family member A9B [Source:HGNC Symbol;Acc:HGNC:31909]",0,0,1,0,1,1,"no","no"]
["MSTRG.12198","AC093281.1","ENST00000514239","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000277007","AC096642.1","ENST00000612055","NA","NA","NA","NA",null,{"v":0.060695,"d":"0.06"},{"v":0.019469,"d":"0.02"},{"v":3.11752016025476,"d":"3.12"},{"v":1.64039888964774,"d":"1.64"},1,1,"up","no"]
["ENSG00000272980","Z94721.2","ENST00000609590","NA","NA","NA","NA",null,{"v":0.065463,"d":"0.07"},{"v":0.032531,"d":"0.03"},{"v":2.01232670375949,"d":"2.01"},{"v":1.00886454750465,"d":"1.01"},1,1,"up","no"]
["ENSG00000081818","PCDHB4","ENST00000194152","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005509(calcium ion binding);GO:0007155(cell adhesion);GO:0007156(homophilic cell adhesion via plasma membrane adhesion molecules);GO:0005886(plasma membrane);GO:0005887(integral component of plasma membrane);GO:0007268(chemical synaptic transmission);GO:0007399(nervous system development);GO:0007416(synapse assembly);GO:0016339(calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules)","NA","NA","NA","protocadherin beta 4 [Source:HGNC Symbol;Acc:HGNC:8689]",0,0,1,0,1,1,"no","no"]
["ENSG00000183709","IFNL2","ENST00000331982","GO:0005622(intracellular);GO:0005576(extracellular region);GO:0005125(cytokine activity);GO:0005615(extracellular space);GO:0051607(defense response to virus);GO:0045087(innate immune response);GO:0007259(JAK-STAT cascade);GO:0050778(positive regulation of immune response);GO:0002385(mucosal immune response);GO:0005102(receptor binding);GO:0050863(regulation of T cell activation)","04630(Jak-STAT signaling pathway);04060(Cytokine-cytokine receptor interaction)","K05447","NA","interferon lambda 2 [Source:HGNC Symbol;Acc:HGNC:18364]",0,0,1,0,1,1,"no","no"]
["ENSG00000227245","AC092042.1","ENST00000457115","NA","NA","NA","NA",null,{"v":0.137107,"d":"0.14"},0,"inf","inf",1,1,"up","no"]
["ENSG00000277954","AC092376.2","ENST00000622621","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000196344","ADH7","ENST00000437033","GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0005829(cytosol);GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0005886(plasma membrane);GO:0005737(cytoplasm);GO:0004745(retinol dehydrogenase activity);GO:0009617(response to bacterium);GO:1900116(extracellular negative regulation of signal transduction);GO:0048019(receptor antagonist activity);GO:0004022(alcohol dehydrogenase (NAD) activity);GO:0004024(alcohol dehydrogenase activity, zinc-dependent);GO:0006069(ethanol oxidation);GO:0001523(retinoid metabolic process);GO:0045471(response to ethanol);GO:0019841(retinol binding);GO:0004031(aldehyde oxidase activity);GO:0035276(ethanol binding);GO:0006068(ethanol catabolic process);GO:0010430(fatty acid omega-oxidation);GO:0042572(retinol metabolic process);GO:0042573(retinoic acid metabolic process);GO:0005576(extracellular region);GO:0005622(intracellular)","00010(Glycolysis / Gluconeogenesis);00071(Fatty acid degradation);00350(Tyrosine metabolism);00830(Retinol metabolism);00980(Metabolism of xenobiotics by cytochrome P450);00982(Drug metabolism - cytochrome P450);05204(Chemical carcinogenesis)","NA","NA","alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide [Source:HGNC Symbol;Acc:HGNC:256]",0,0,1,0,1,1,"no","no"]
["ENSG00000254119","AC025524.2","ENST00000520862","NA","NA","NA","NA",null,0,{"v":0.00235007543581616,"d":"0.00"},"-inf","-inf",1,1,"down","no"]
["ENSG00000205930","C21orf62-AS1","ENST00000477513;ENST00000612326;ENST00000382375;ENST00000454365;ENST00000382378","NA","NA","NA","NA","C21orf62 antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:1290]",{"v":0.0957620784817352,"d":"0.10"},{"v":0.134394206335616,"d":"0.13"},{"v":0.712546181065226,"d":"0.71"},{"v":-0.488944574709,"d":"-0.49"},1,1,"down","no"]
["ENSG00000204011","COL5A1-AS1","ENST00000371813","NA","NA","NA","NA","COL5A1 antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:31368]",0,0,1,0,1,1,"no","no"]
["ENSG00000164744","SUN3","ENST00000473723;ENST00000461953;ENST00000438771;ENST00000449896","GO:0005634(nucleus);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005637(nuclear inner membrane);GO:0005635(nuclear envelope);GO:0043495(protein anchor);GO:0006998(nuclear envelope organization);GO:0090286(cytoskeletal anchoring at nuclear membrane);GO:0034993(LINC complex);GO:0034993(LINC complex)","NA","NA","NA","Sad1 and UNC84 domain containing 3 [Source:HGNC Symbol;Acc:HGNC:22429]",{"v":0.0188895404157044,"d":"0.02"},{"v":1.5568648960739E-3,"d":"0.00"},{"v":12.1330633527289,"d":"12.13"},{"v":3.60087194261112,"d":"3.60"},1,1,"up","no"]
["ENSG00000157150","TIMP4","ENST00000287814","GO:0046872(metal ion binding);GO:0010951(negative regulation of endopeptidase activity);GO:0005576(extracellular region);GO:0005615(extracellular space);GO:0030414(peptidase inhibitor activity);GO:0010466(negative regulation of peptidase activity);GO:0008191(metalloendopeptidase inhibitor activity);GO:0008150(biological_process);GO:0005578(proteinaceous extracellular matrix);GO:0034097(response to cytokine);GO:0004857(enzyme inhibitor activity);GO:0002020(protease binding);GO:0009725(response to hormone);GO:0051045(negative regulation of membrane protein ectodomain proteolysis);GO:0007219(Notch signaling pathway);GO:0007417(central nervous system development);GO:0032496(response to lipopolysaccharide);GO:0042493(response to drug);GO:0042698(ovulation cycle);GO:0043086(negative regulation of catalytic activity);GO:0043434(response to peptide hormone);GO:0030017(sarcomere)","NA","NA","NA","TIMP metallopeptidase inhibitor 4 [Source:HGNC Symbol;Acc:HGNC:11823]",0,0,1,0,1,1,"no","no"]
["ENSG00000225117","ARSDP1","ENST00000443820","NA","NA","NA","NA","arylsulfatase D pseudogene 1 [Source:HGNC Symbol;Acc:HGNC:718]",0,0,1,0,1,1,"no","no"]
["ENSG00000196104","SPOCK3","ENST00000421836","GO:0005509(calcium ion binding);GO:0007165(signal transduction);GO:0005576(extracellular region);GO:0005578(proteinaceous extracellular matrix);GO:0030414(peptidase inhibitor activity);GO:0010466(negative regulation of peptidase activity);GO:0004857(enzyme inhibitor activity);GO:0008191(metalloendopeptidase inhibitor activity);GO:0010951(negative regulation of endopeptidase activity);GO:0005539(glycosaminoglycan binding);GO:0019800(peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan);GO:2000146(negative regulation of cell motility)","NA","NA","NA","SPARC/osteonectin, cwcv and kazal like domains proteoglycan 3 [Source:HGNC Symbol;Acc:HGNC:13565]",{"v":0.0231541907630522,"d":"0.02"},{"v":0.0113547938420348,"d":"0.01"},{"v":2.03915553951642,"d":"2.04"},{"v":1.02797182318713,"d":"1.03"},1,1,"up","no"]
["ENSG00000113657","DPYSL3","ENST00000343218","GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0016787(hydrolase activity);GO:0042995(cell projection);GO:0005515(protein binding);GO:0016810(hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds);GO:0005615(extracellular space);GO:0051017(actin filament bundle assembly);GO:0030334(regulation of cell migration);GO:0010975(regulation of neuron projection development);GO:0048678(response to axon injury);GO:0051491(positive regulation of filopodium assembly);GO:0030027(lamellipodium);GO:0030426(growth cone);GO:0031941(filamentous actin);GO:0017124(SH3 domain binding);GO:0035374(chondroitin sulfate binding);GO:0031005(filamin binding);GO:0030336(negative regulation of cell migration);GO:0051260(protein homooligomerization);GO:0010976(positive regulation of neuron projection development);GO:0010977(negative regulation of neuron projection development);GO:0071345(cellular response to cytokine stimulus);GO:0070382(exocytic vesicle);GO:0044297(cell body);GO:0051764(actin crosslink formation);GO:0048666(neuron development)","NA","NA","NA","dihydropyrimidinase like 3 [Source:HGNC Symbol;Acc:HGNC:3015]",{"v":0.0296593735343384,"d":"0.03"},{"v":0.00715075097710776,"d":"0.01"},{"v":4.14772848743988,"d":"4.15"},{"v":2.05232145764089,"d":"2.05"},1,1,"up","no"]
["ENSG00000205106","DKFZp779M0652","ENST00000378779","NA","NA","NA","NA","uncharacterized DKFZp779M0652 [Source:NCBI gene;Acc:374387]",{"v":0.081849,"d":"0.08"},{"v":0.156832,"d":"0.16"},{"v":0.521889665374413,"d":"0.52"},{"v":-0.938183261353352,"d":"-0.94"},1,1,"down","no"]
["ENSG00000273156","AC124016.2","ENST00000610058","NA","NA","NA","NA",null,0,{"v":0.153058,"d":"0.15"},"-inf","-inf",1,1,"down","no"]
["ENSG00000188425","NANOS2","ENST00000341294","GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0005515(protein binding);GO:0007275(multicellular organism development);GO:0048471(perinuclear region of cytoplasm);GO:0030154(cell differentiation);GO:0007283(spermatogenesis);GO:0000932(P-body);GO:0006417(regulation of translation);GO:0017148(negative regulation of translation);GO:0006402(mRNA catabolic process);GO:0003729(mRNA binding);GO:0030718(germ-line stem cell population maintenance);GO:0045835(negative regulation of meiotic nuclear division);GO:1900153(positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)","NA","NA","NA","nanos C2HC-type zinc finger 2 [Source:HGNC Symbol;Acc:HGNC:23292]",0,0,1,0,1,1,"no","no"]
["ENSG00000267197","AC011461.1","ENST00000592671","NA","NA","NA","NA",null,0,{"v":0.192019,"d":"0.19"},"-inf","-inf",1,1,"down","no"]
["ENSG00000277027","RMRP","ENST00000363046","NA","NA","NA","NA","RNA component of mitochondrial RNA processing endoribonuclease [Source:HGNC Symbol;Acc:HGNC:10031]",{"v":0.301817,"d":"0.30"},{"v":1.059289,"d":"1.06"},{"v":0.284924133074166,"d":"0.28"},{"v":-1.81135027177985,"d":"-1.81"},1,1,"down","no"]
["ENSG00000234286","AC006026.3","ENST00000454029","NA","NA","NA","NA",null,{"v":0.029521,"d":"0.03"},0,"inf","inf",1,1,"up","no"]
["ENSG00000127863","TNFRSF19","ENST00000382263;ENST00000403372","GO:0005622(intracellular);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0006915(apoptotic process);GO:0005886(plasma membrane);GO:0009888(tissue development);GO:0033209(tumor necrosis factor-mediated signaling pathway);GO:0004872(receptor activity);GO:0007254(JNK cascade);GO:0005031(tumor necrosis factor-activated receptor activity);GO:0046330(positive regulation of JNK cascade);GO:0043123(positive regulation of I-kappaB kinase/NF-kappaB signaling);GO:0001942(hair follicle development);GO:0001942(hair follicle development)","04060(Cytokine-cytokine receptor interaction);04060(Cytokine-cytokine receptor interaction)","K05155","NA","TNF receptor superfamily member 19 [Source:HGNC Symbol;Acc:HGNC:11915]",{"v":0.0519455159397614,"d":"0.05"},{"v":0.049799822217876,"d":"0.05"},{"v":1.04308637312997,"d":"1.04"},{"v":0.0608586256687385,"d":"0.06"},1,1,"up","no"]
["ENSG00000197893","NRAP","ENST00000359988","GO:0046872(metal ion binding);GO:0003779(actin binding);GO:0005515(protein binding);GO:0008150(biological_process);GO:0051371(muscle alpha-actinin binding);GO:0005916(fascia adherens);GO:0005927(muscle tendon junction);GO:0017166(vinculin binding);GO:0030016(myofibril)","NA","NA","NA","nebulin related anchoring protein [Source:HGNC Symbol;Acc:HGNC:7988]",0,0,1,0,1,1,"no","no"]
["ENSG00000214514","KRT42P","ENST00000398469","NA","NA","NA","NA","keratin 42 pseudogene [Source:HGNC Symbol;Acc:HGNC:27581]",0,0,1,0,1,1,"no","no"]
["ENSG00000250220","AC053527.1","ENST00000502790","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000143171","RXRG","ENST00000619224","GO:0005634(nucleus);GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0043565(sequence-specific DNA binding);GO:0005515(protein binding);GO:0003707(steroid hormone receptor activity);GO:0043401(steroid hormone mediated signaling pathway);GO:0005654(nucleoplasm);GO:0000977(RNA polymerase II regulatory region sequence-specific DNA binding);GO:0004886(9-cis retinoic acid receptor activity);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0048384(retinoic acid receptor signaling pathway);GO:0051289(protein homotetramerization);GO:1901522(positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus);GO:0006367(transcription initiation from RNA polymerase II promoter)","04659(Th17 cell differentiation);04920(Adipocytokine signaling pathway);03320(PPAR signaling pathway);04919(Thyroid hormone signaling pathway);05200(Pathways in cancer);05202(Transcriptional misregulation in cancers);05226(Gastric cancer);05216(Thyroid cancer);05222(Small cell lung cancer);05223(Non-small cell lung cancer)","K08526","NA","retinoid X receptor gamma [Source:HGNC Symbol;Acc:HGNC:10479]",0,0,1,0,1,1,"no","no"]
["ENSG00000271833","AL445222.1","ENST00000607259","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000196428","TSC22D2","ENST00000460316;ENST00000492828;ENST00000485421;ENST00000466814;ENST00000361875","GO:0006355(regulation of transcription, DNA-templated);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0006970(response to osmotic stress);GO:0006970(response to osmotic stress)","NA","NA","NA","TSC22 domain family member 2 [Source:HGNC Symbol;Acc:HGNC:29095]",{"v":0.0262753138917437,"d":"0.03"},{"v":0.0117626184480987,"d":"0.01"},{"v":2.23379802785245,"d":"2.23"},{"v":1.1594987483153,"d":"1.16"},1,1,"up","no"]
["ENSG00000163288","GABRB1","ENST00000295454","GO:0016021(integral component of membrane);GO:0005216(ion channel activity);GO:0006811(ion transport);GO:0034220(ion transmembrane transport);GO:0005230(extracellular ligand-gated ion channel activity);GO:0006810(transport);GO:0016020(membrane);GO:0005886(plasma membrane);GO:0030054(cell junction);GO:0045202(synapse);GO:0045211(postsynaptic membrane);GO:0005254(chloride channel activity);GO:0006821(chloride transport);GO:0034707(chloride channel complex);GO:0004890(GABA-A receptor activity);GO:0007165(signal transduction);GO:0098656(anion transmembrane transport);GO:0005887(integral component of plasma membrane);GO:0007214(gamma-aminobutyric acid signaling pathway);GO:1902711(GABA-A receptor complex);GO:1902476(chloride transmembrane transport);GO:0015276(ligand-gated ion channel activity);GO:0022851(GABA-gated chloride ion channel activity);GO:0005253(anion channel activity);GO:0050811(GABA receptor binding);GO:0009636(response to toxic substance);GO:0021954(central nervous system neuron development);GO:0032570(response to progesterone);GO:0042698(ovulation cycle);GO:0071420(cellular response to histamine);GO:0005634(nucleus);GO:0005635(nuclear envelope);GO:0005737(cytoplasm);GO:0030425(dendrite);GO:0043235(receptor complex)","04080(Neuroactive ligand-receptor interaction);04727(GABAergic synapse);04726(Serotonergic synapse);04723(Retrograde endocannabinoid signaling);05032(Morphine addiction);05033(Nicotine addiction)","K05181","NA","gamma-aminobutyric acid type A receptor beta1 subunit [Source:HGNC Symbol;Acc:HGNC:4081]",0,0,1,0,1,1,"no","no"]
["ENSG00000185924","RTN4RL1","ENST00000331238","GO:0016020(membrane);GO:0005886(plasma membrane);GO:0042995(cell projection);GO:0005515(protein binding);GO:0031225(anchored component of membrane);GO:0045121(membrane raft);GO:0005576(extracellular region);GO:0005737(cytoplasm);GO:0008201(heparin binding);GO:0043204(perikaryon);GO:0070062(extracellular exosome);GO:0004872(receptor activity);GO:0006501(C-terminal protein lipidation);GO:0004860(protein kinase inhibitor activity);GO:0006469(negative regulation of protein kinase activity);GO:0019221(cytokine-mediated signaling pathway);GO:0046426(negative regulation of JAK-STAT cascade);GO:0035374(chondroitin sulfate binding);GO:0046658(anchored component of plasma membrane);GO:0010977(negative regulation of neuron projection development);GO:0009986(cell surface);GO:0048681(negative regulation of axon regeneration);GO:0022038(corpus callosum development);GO:0031103(axon regeneration);GO:0009897(external side of plasma membrane)","NA","NA","NA","reticulon 4 receptor like 1 [Source:HGNC Symbol;Acc:HGNC:21329]",{"v":0.196273,"d":"0.20"},{"v":0.042117,"d":"0.04"},{"v":4.66018472350832,"d":"4.66"},{"v":2.22038714252064,"d":"2.22"},1,1,"up","no"]
["ENSG00000266356","AC090615.1","ENST00000577519","NA","NA","NA","NA",null,{"v":0.028334,"d":"0.03"},{"v":0.07852,"d":"0.08"},{"v":0.360850738665308,"d":"0.36"},{"v":-1.47052588690859,"d":"-1.47"},1,1,"down","no"]
["ENSG00000272588","AC139887.4","ENST00000607877","NA","NA","NA","NA",null,0,{"v":0.070781,"d":"0.07"},"-inf","-inf",1,1,"down","no"]
["ENSG00000229867","STEAP3-AS1","ENST00000454260","NA","NA","NA","NA","STEAP3 antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:41053]",{"v":0.005881,"d":"0.01"},0,"inf","inf",1,1,"up","no"]
["ENSG00000251636","LINC01218","ENST00000515150","NA","NA","NA","NA","long intergenic non-protein coding RNA 1218 [Source:HGNC Symbol;Acc:HGNC:41420]",{"v":0.001463,"d":"0.00"},{"v":0.105804,"d":"0.11"},{"v":0.0138274545385808,"d":"0.01"},{"v":-6.17632059095516,"d":"-6.18"},1,1,"down","no"]
["ENSG00000234515","PPP1R2P1","ENST00000420261;ENST00000429032","NA","NA","NA","NA","protein phosphatase 1 regulatory inhibitor subunit 2 pseudogene 1 [Source:HGNC Symbol;Acc:HGNC:9289]",0,0,1,0,1,1,"no","no"]
["ENSG00000198354","DCAF12L2","ENST00000360028","NA","NA","NA","NA","DDB1 and CUL4 associated factor 12 like 2 [Source:HGNC Symbol;Acc:HGNC:32950]",0,0,1,0,1,1,"no","no"]
["ENSG00000233270","SNRPEP4","ENST00000435815","NA","NA","NA","NA","small nuclear ribonucleoprotein polypeptide E pseudogene 4 [Source:HGNC Symbol;Acc:HGNC:43446]",0,{"v":1.491577,"d":"1.49"},"-inf","-inf",1,1,"down","no"]
["MSTRG.5905","ORC6","ENST00000566860;ENST00000219097;ENST00000567000;ENST00000563306","GO:0006260(DNA replication);GO:0005664(nuclear origin of replication recognition complex);GO:0005634(nucleus);GO:0016020(membrane);GO:0003677(DNA binding);GO:0001650(fibrillar center);GO:0005515(protein binding);GO:0005654(nucleoplasm);GO:0000082(G1/S transition of mitotic cell cycle);GO:0006270(DNA replication initiation);GO:0000808(origin recognition complex);GO:0003688(DNA replication origin binding);GO:0051782(negative regulation of cell division);GO:0051782(negative regulation of cell division)","04110(Cell cycle);04110(Cell cycle)","K02608","NA","origin recognition complex subunit 6 [Source:HGNC Symbol;Acc:HGNC:17151]",{"v":0.132517172893943,"d":"0.13"},{"v":0.034766971455094,"d":"0.03"},{"v":3.8115822962925,"d":"3.81"},{"v":1.93039002583598,"d":"1.93"},1,1,"up","no"]
["ENSG00000180660","MAB21L1","ENST00000379919","GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0016740(transferase activity);GO:0005525(GTP binding);GO:0005515(protein binding);GO:0007275(multicellular organism development);GO:0016779(nucleotidyltransferase activity);GO:0008284(positive regulation of cell proliferation);GO:0043010(camera-type eye development);GO:0009653(anatomical structure morphogenesis)","NA","NA","NA","mab-21 like 1 [Source:HGNC Symbol;Acc:HGNC:6757]",0,0,1,0,1,1,"no","no"]
["ENSG00000213638","ADAT3","ENST00000454697;ENST00000329478","GO:0003824(catalytic activity);GO:0003824(catalytic activity)","NA","NA","NA","adenosine deaminase, tRNA specific 3 [Source:HGNC Symbol;Acc:HGNC:25151]",{"v":0.444875753240948,"d":"0.44"},{"v":0.259535297273134,"d":"0.26"},{"v":1.71412427486795,"d":"1.71"},{"v":0.777471709354849,"d":"0.78"},1,1,"up","no"]
["MSTRG.3809","AC145422.1","ENST00000541574","NA","NA","NA","NA",null,{"v":0.539789,"d":"0.54"},{"v":0.761816,"d":"0.76"},{"v":0.708555609228475,"d":"0.71"},{"v":-0.497047010960933,"d":"-0.50"},1,1,"down","no"]
["ENSG00000281508","CDR1","ENST00000625883","NA","NA","NA","NA","cerebellar degeneration related protein 1 [Source:HGNC Symbol;Acc:HGNC:1798]",0,0,1,0,1,1,"no","no"]
["MSTRG.12284","LEAP2","ENST00000483190;ENST00000296877","GO:0005576(extracellular region);GO:0042742(defense response to bacterium);GO:0019730(antimicrobial humoral response);GO:0019730(antimicrobial humoral response)","NA","NA","NA","liver enriched antimicrobial peptide 2 [Source:HGNC Symbol;Acc:HGNC:29571]",{"v":0.0865443455301455,"d":"0.09"},{"v":0.0178676361746362,"d":"0.02"},{"v":4.84363710365888,"d":"4.84"},{"v":2.27609077907767,"d":"2.28"},1,1,"up","no"]
["ENSG00000188585","CLEC20A","ENST00000623247","NA","NA","NA","NA","C-type lectin domain containing 20A [Source:HGNC Symbol;Acc:HGNC:34521]",{"v":0.0261396114583333,"d":"0.03"},{"v":0.052953796875,"d":"0.05"},{"v":0.493630542112724,"d":"0.49"},{"v":-1.01849643461519,"d":"-1.02"},1,1,"down","no"]
["ENSG00000003249","DBNDD1","ENST00000002501;ENST00000623401;ENST00000568662;ENST00000304733;ENST00000392973","GO:0005737(cytoplasm);GO:0030672(synaptic vesicle membrane);GO:0031175(neuron projection development);GO:0031175(neuron projection development)","NA","NA","NA","dysbindin domain containing 1 [Source:HGNC Symbol;Acc:HGNC:28455]",{"v":0.29918988123565,"d":"0.30"},{"v":0.0354089386349405,"d":"0.04"},{"v":8.44955801472169,"d":"8.45"},{"v":3.0788758778864,"d":"3.08"},1,1,"up","no"]
["ENSG00000237672","KRR1P1","ENST00000419430","NA","NA","NA","NA","KRR1, small subunit processome component homolog pseudogene 1 [Source:HGNC Symbol;Acc:HGNC:39580]",{"v":0.139894,"d":"0.14"},{"v":0.151431,"d":"0.15"},{"v":0.92381348601013,"d":"0.92"},{"v":-0.114326487802034,"d":"-0.11"},1,1,"down","no"]
["ENSG00000182308","DCAF4L1","ENST00000333141","NA","NA","NA","NA","DDB1 and CUL4 associated factor 4 like 1 [Source:HGNC Symbol;Acc:HGNC:27723]",{"v":0.077921,"d":"0.08"},{"v":0.053112,"d":"0.05"},{"v":1.46710724506703,"d":"1.47"},{"v":0.552974335408823,"d":"0.55"},1,1,"up","no"]
["MSTRG.11095","ZBTB11-AS1","ENST00000609682","NA","NA","NA","NA","ZBTB11 antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:48573]",{"v":0.383756,"d":"0.38"},0,"inf","inf",1,1,"up","no"]
["ENSG00000228223","HCG11","ENST00000411553","NA","NA","NA","NA","HLA complex group 11 (non-protein coding) [Source:HGNC Symbol;Acc:HGNC:17707]",0,{"v":0.75344,"d":"0.75"},"-inf","-inf",1,1,"down","no"]
["MSTRG.1953",null,"MSTRG.1953.1","NA","NA","NA","NA",null,0,{"v":2.925699,"d":"2.93"},"-inf","-inf",1,1,"down","no"]
["ENSG00000259417","CTXND1","ENST00000560778","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0031224(intrinsic component of membrane)","NA","NA","NA","cortexin domain containing 1 [Source:HGNC Symbol;Acc:HGNC:50507]",0,0,1,0,1,1,"no","no"]
["ENSG00000105605","CACNG7","ENST00000391767","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005244(voltage-gated ion channel activity);GO:0006811(ion transport);GO:0034765(regulation of ion transmembrane transport);GO:0006816(calcium ion transport);GO:0005262(calcium channel activity);GO:0070588(calcium ion transmembrane transport);GO:0005886(plasma membrane);GO:0032281(AMPA glutamate receptor complex);GO:0061337(cardiac conduction);GO:0005245(voltage-gated calcium channel activity);GO:0005891(voltage-gated calcium channel complex);GO:0016247(channel regulator activity);GO:0019226(transmission of nerve impulse);GO:2000311(regulation of AMPA receptor activity)","04010(MAPK signaling pathway);04921(Oxytocin signaling pathway);04260(Cardiac muscle contraction);04261(Adrenergic signaling in cardiomyocytes);05410(Hypertrophic cardiomyopathy (HCM));05412(Arrhythmogenic right ventricular cardiomyopathy (ARVC));05414(Dilated cardiomyopathy (DCM))","K04872","NA","calcium voltage-gated channel auxiliary subunit gamma 7 [Source:HGNC Symbol;Acc:HGNC:13626]",0,0,1,0,1,1,"no","no"]
["MSTRG.8267","AC008622.2","ENST00000612522;ENST00000617006","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["MSTRG.13742","AC006330.1","ENST00000624598","NA","NA","NA","NA",null,0,{"v":0.076837,"d":"0.08"},"-inf","-inf",1,1,"down","no"]
["ENSG00000196132","MYT1","ENST00000536311","GO:0005634(nucleus);GO:0008270(zinc ion binding);GO:0006355(regulation of transcription, DNA-templated);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0046872(metal ion binding);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0007275(multicellular organism development);GO:0007399(nervous system development);GO:0030154(cell differentiation)","NA","NA","NA","myelin transcription factor 1 [Source:HGNC Symbol;Acc:HGNC:7622]",0,{"v":0.0162461005586592,"d":"0.02"},"-inf","-inf",1,1,"down","no"]
["ENSG00000257763","OR5BK1P","ENST00000550421","NA","NA","NA","NA","olfactory receptor family 5 subfamily BK member 1 pseudogene [Source:HGNC Symbol;Acc:HGNC:14817]",0,{"v":0.061837,"d":"0.06"},"-inf","-inf",1,1,"down","no"]
["MSTRG.6778","AC009283.1","ENST00000615852","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000250992","AC139491.3","ENST00000509643","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000196475","GK2","ENST00000358842","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0016773(phosphotransferase activity, alcohol group as acceptor);GO:0005975(carbohydrate metabolic process);GO:0005739(mitochondrion);GO:0006072(glycerol-3-phosphate metabolic process);GO:0005741(mitochondrial outer membrane);GO:0004370(glycerol kinase activity);GO:0070062(extracellular exosome);GO:0006071(glycerol metabolic process);GO:0019563(glycerol catabolic process);GO:0006641(triglyceride metabolic process);GO:0046167(glycerol-3-phosphate biosynthetic process)","00561(Glycerolipid metabolism);03320(PPAR signaling pathway)","K00864","EC:2.7.1.30","glycerol kinase 2 [Source:HGNC Symbol;Acc:HGNC:4291]",0,0,1,0,1,1,"no","no"]
["ENSG00000133980","VRTN","ENST00000256362","GO:0003677(DNA binding);GO:0043565(sequence-specific DNA binding);GO:0004803(transposase activity);GO:0006313(transposition, DNA-mediated)","NA","NA","NA","vertebrae development associated [Source:HGNC Symbol;Acc:HGNC:20223]",0,0,1,0,1,1,"no","no"]
["ENSG00000159650","UROC1","ENST00000290868","GO:0016829(lyase activity);GO:0005829(cytosol);GO:0006548(histidine catabolic process);GO:0006547(histidine metabolic process);GO:0019556(histidine catabolic process to glutamate and formamide);GO:0019557(histidine catabolic process to glutamate and formate);GO:0016153(urocanate hydratase activity)","00340(Histidine metabolism)","K01712","EC:4.2.1.49","urocanate hydratase 1 [Source:HGNC Symbol;Acc:HGNC:26444]",0,{"v":0.0305752859717633,"d":"0.03"},"-inf","-inf",1,1,"down","no"]
["ENSG00000229462","AC127383.1","ENST00000444697","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000271013","LRRC37A9P","ENST00000603850","NA","NA","NA","NA","leucine rich repeat containing 37 member A9, pseudogene [Source:HGNC Symbol;Acc:HGNC:43813]",{"v":0.049274,"d":"0.05"},{"v":0.009373,"d":"0.01"},{"v":5.25701482983036,"d":"5.26"},{"v":2.39424380470103,"d":"2.39"},1,1,"up","no"]
["ENSG00000237473","AC068759.1","ENST00000447709","NA","NA","NA","NA",null,{"v":0.101419,"d":"0.10"},{"v":0.05414,"d":"0.05"},{"v":1.87327299593646,"d":"1.87"},{"v":0.905561161825509,"d":"0.91"},1,1,"up","no"]
["MSTRG.4505","RPL7AP6","ENST00000477943","NA","NA","NA","NA","ribosomal protein L7a pseudogene 6 [Source:HGNC Symbol;Acc:HGNC:19785]",0,0,1,0,1,1,"no","no"]
["ENSG00000101213","PTK6","ENST00000542869","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0004713(protein tyrosine kinase activity);GO:0005886(plasma membrane);GO:0042995(cell projection);GO:0005515(protein binding);GO:0016604(nuclear body);GO:0004715(non-membrane spanning protein tyrosine kinase activity);GO:0045087(innate immune response);GO:0042802(identical protein binding);GO:0001726(ruffle);GO:0042127(regulation of cell proliferation);GO:0016477(cell migration);GO:0046777(protein autophosphorylation);GO:0038128(ERBB2 signaling pathway);GO:0042531(positive regulation of tyrosine phosphorylation of STAT protein);GO:0005102(receptor binding);GO:0038083(peptidyl-tyrosine autophosphorylation);GO:0031234(extrinsic component of cytoplasmic side of plasma membrane);GO:0007169(transmembrane receptor protein tyrosine kinase signaling pathway);GO:0061099(negative regulation of protein tyrosine kinase activity);GO:0010976(positive regulation of neuron projection development);GO:0071300(cellular response to retinoic acid);GO:0045742(positive regulation of epidermal growth factor receptor signaling pathway);GO:0045787(positive regulation of cell cycle);GO:0007260(tyrosine phosphorylation of STAT protein);GO:0009968(negative regulation of signal transduction);GO:0045926(negative regulation of growth);GO:0060575(intestinal epithelial cell differentiation)","NA","NA","NA","protein tyrosine kinase 6 [Source:HGNC Symbol;Acc:HGNC:9617]",{"v":0.182398308109942,"d":"0.18"},{"v":0.111511272480489,"d":"0.11"},{"v":1.6356938993935,"d":"1.64"},{"v":0.7099027903668,"d":"0.71"},1,1,"up","no"]
["ENSG00000198515","CNGA1","ENST00000402813","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0055085(transmembrane transport);GO:0000166(nucleotide binding);GO:0005216(ion channel activity);GO:0006811(ion transport);GO:0007601(visual perception);GO:0005515(protein binding);GO:0071805(potassium ion transmembrane transport);GO:0005221(intracellular cyclic nucleotide activated cation channel activity);GO:0098655(cation transmembrane transport);GO:0050896(response to stimulus);GO:0005886(plasma membrane);GO:0030553(cGMP binding);GO:0005887(integral component of plasma membrane);GO:0005249(voltage-gated potassium channel activity);GO:0022400(regulation of rhodopsin mediated signaling pathway);GO:0042391(regulation of membrane potential);GO:0016056(rhodopsin mediated signaling pathway);GO:0001750(photoreceptor outer segment);GO:0042622(photoreceptor outer segment membrane)","04024(cAMP signaling pathway);04022(cGMP - PKG signaling pathway);04744(Phototransduction)","K04948","NA","cyclic nucleotide gated channel alpha 1 [Source:HGNC Symbol;Acc:HGNC:2148]",0,{"v":0.0282352664060318,"d":"0.03"},"-inf","-inf",1,1,"down","no"]
["ENSG00000089225","TBX5","ENST00000310346;ENST00000552726","GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0005515(protein binding);GO:0007275(multicellular organism development);GO:0045893(positive regulation of transcription, DNA-templated);GO:0005654(nucleoplasm);GO:0007507(heart development);GO:0008285(negative regulation of cell proliferation);GO:0043565(sequence-specific DNA binding);GO:0006367(transcription initiation from RNA polymerase II promoter);GO:0007267(cell-cell signaling);GO:0035115(embryonic forelimb morphogenesis);GO:0035136(forelimb morphogenesis);GO:0030336(negative regulation of cell migration);GO:0032993(protein-DNA complex);GO:0008134(transcription factor binding);GO:0032991(macromolecular complex);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:0003218(cardiac left ventricle formation);GO:0060039(pericardium development);GO:0030326(embryonic limb morphogenesis);GO:0003281(ventricular septum development);GO:0051891(positive regulation of cardioblast differentiation);GO:0060044(negative regulation of cardiac muscle cell proliferation);GO:0010719(negative regulation of epithelial to mesenchymal transition);GO:0060980(cell migration involved in coronary vasculogenesis);GO:1900117(regulation of execution phase of apoptosis);GO:0000977(RNA polymerase II regulatory region sequence-specific DNA binding);GO:0001228(transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding);GO:0002009(morphogenesis of an epithelium);GO:0003166(bundle of His development);GO:0003181(atrioventricular valve morphogenesis);GO:0003197(endocardial cushion development);GO:0003229(ventricular cardiac muscle tissue development);GO:0003283(atrial septum development);GO:0007389(pattern specification process);GO:0030324(lung development);GO:0055007(cardiac muscle cell differentiation);GO:0060045(positive regulation of cardiac muscle cell proliferation);GO:0060413(atrial septum morphogenesis);GO:0072513(positive regulation of secondary heart field cardioblast proliferation);GO:0072513(positive regulation of secondary heart field cardioblast proliferation)","NA","NA","NA","T-box 5 [Source:HGNC Symbol;Acc:HGNC:11604]",0,0,1,0,1,1,"no","no"]
["ENSG00000280757","DUX4L1","ENST00000627662","NA","NA","NA","NA","double homeobox 4 like 1 [Source:HGNC Symbol;Acc:HGNC:3082]",0,0,1,0,1,1,"no","no"]
["ENSG00000270638","AL023806.1","ENST00000603994","NA","NA","NA","NA",null,{"v":0.159147,"d":"0.16"},{"v":0.030862,"d":"0.03"},{"v":5.15672995917309,"d":"5.16"},{"v":2.36645649836585,"d":"2.37"},1,1,"up","no"]
["ENSG00000216360","AL136968.1","ENST00000403053","NA","NA","NA","NA",null,{"v":0.224608,"d":"0.22"},0,"inf","inf",1,1,"up","no"]
["ENSG00000197245","FAM110D","ENST00000374268","NA","NA","NA","NA","family with sequence similarity 110 member D [Source:HGNC Symbol;Acc:HGNC:25860]",0,0,1,0,1,1,"no","no"]
["ENSG00000141748","ARL5C","ENST00000581554;ENST00000581255;ENST00000269586","GO:0005525(GTP binding);GO:0007264(small GTPase mediated signal transduction);GO:0000166(nucleotide binding);GO:0005622(intracellular);GO:0005622(intracellular)","NA","NA","NA","ADP ribosylation factor like GTPase 5C [Source:HGNC Symbol;Acc:HGNC:31111]",{"v":0.105679316559391,"d":"0.11"},{"v":0.0446678689291984,"d":"0.04"},{"v":2.3658911672482,"d":"2.37"},{"v":1.24238371016012,"d":"1.24"},1,1,"up","no"]
["MSTRG.2048",null,"MSTRG.2048.1","NA","NA","NA","NA",null,0,{"v":0.745656,"d":"0.75"},"-inf","-inf",1,1,"down","no"]
["MSTRG.15341","KIF4A","ENST00000374403","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0005654(nucleoplasm);GO:0003677(DNA binding);GO:0005694(chromosome);GO:1904115(axon cytoplasm);GO:0045171(intercellular bridge);GO:0003777(microtubule motor activity);GO:0005856(cytoskeleton);GO:0008017(microtubule binding);GO:0005874(microtubule);GO:0007018(microtubule-based movement);GO:0005819(spindle);GO:0030496(midbody);GO:0005515(protein binding);GO:0005829(cytosol);GO:0006890(retrograde vesicle-mediated transport, Golgi to ER);GO:0019886(antigen processing and presentation of exogenous peptide antigen via MHC class II);GO:0005871(kinesin complex);GO:0016363(nuclear matrix);GO:0008574(ATP-dependent microtubule motor activity, plus-end-directed);GO:0000281(mitotic cytokinesis);GO:0008089(anterograde axonal transport);GO:0005876(spindle microtubule);GO:0006996(organelle organization);GO:0051256(mitotic spindle midzone assembly)","NA","NA","NA","kinesin family member 4A [Source:HGNC Symbol;Acc:HGNC:13339]",{"v":0.0584759479373483,"d":"0.06"},{"v":0.0448516390911096,"d":"0.04"},{"v":1.30376390076989,"d":"1.30"},{"v":0.382682634884924,"d":"0.38"},1,1,"up","no"]
["ENSG00000226723","AL513175.1","ENST00000431492","NA","NA","NA","NA",null,0,{"v":0.029166,"d":"0.03"},"-inf","-inf",1,1,"down","no"]
["ENSG00000117594","HSD11B1","ENST00000367028;ENST00000615289;ENST00000367027","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0006629(lipid metabolic process);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0008202(steroid metabolic process);GO:0006704(glucocorticoid biosynthetic process);GO:0003845(11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity);GO:0070524(11-beta-hydroxysteroid dehydrogenase (NADP+) activity);GO:0030324(lung development);GO:0030324(lung development)","00140(Steroid hormone biosynthesis);00980(Metabolism of xenobiotics by cytochrome P450);05204(Chemical carcinogenesis);05204(Chemical carcinogenesis)","K15680","EC:1.1.1.146","hydroxysteroid 11-beta dehydrogenase 1 [Source:HGNC Symbol;Acc:HGNC:5208]",{"v":0.154214655651024,"d":"0.15"},{"v":0.100129195637806,"d":"0.10"},{"v":1.54015674118525,"d":"1.54"},{"v":0.623077180935572,"d":"0.62"},1,1,"up","no"]
["ENSG00000232450","AL133517.1","ENST00000413412","NA","NA","NA","NA",null,{"v":0.3074,"d":"0.31"},{"v":0.178427,"d":"0.18"},{"v":1.7228334276763,"d":"1.72"},{"v":0.784783221190071,"d":"0.78"},1,1,"up","no"]
["MSTRG.11188","EFCAB12","ENST00000505956;ENST00000503498;ENST00000514900","GO:0046872(metal ion binding);GO:0005509(calcium ion binding);GO:0005515(protein binding);GO:0005515(protein binding)","NA","NA","NA","EF-hand calcium binding domain 12 [Source:HGNC Symbol;Acc:HGNC:28061]",{"v":0.105436719347798,"d":"0.11"},{"v":0.0627912036204904,"d":"0.06"},{"v":1.67916385207484,"d":"1.68"},{"v":0.74774301469548,"d":"0.75"},1,1,"up","no"]
["ENSG00000257564","AC068993.1","ENST00000546724","NA","NA","NA","NA",null,{"v":0.076449,"d":"0.08"},{"v":0.067521,"d":"0.07"},{"v":1.13222552983516,"d":"1.13"},{"v":0.17916135955411,"d":"0.18"},1,1,"up","no"]
["ENSG00000253745","AC091163.1","ENST00000524012","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000231701","BMS1P13","ENST00000417301","NA","NA","NA","NA","BMS1, ribosome biogenesis factor pseudogene 13 [Source:HGNC Symbol;Acc:HGNC:49158]",0,{"v":0.014376,"d":"0.01"},"-inf","-inf",1,1,"down","no"]
["ENSG00000021826","CPS1","ENST00000233072","GO:0005634(nucleus);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0005730(nucleolus);GO:0046872(metal ion binding);GO:0003824(catalytic activity);GO:0005739(mitochondrion);GO:0016874(ligase activity);GO:0005515(protein binding);GO:0008152(metabolic process);GO:0006807(nitrogen compound metabolic process);GO:0006508(proteolysis);GO:0004088(carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity);GO:0006207('de novo' pyrimidine nucleobase biosynthetic process);GO:0006541(glutamine metabolic process);GO:0000050(urea cycle);GO:0005759(mitochondrial matrix);GO:0032496(response to lipopolysaccharide);GO:0042645(mitochondrial nucleoid);GO:0019240(citrulline biosynthetic process);GO:0019433(triglyceride catabolic process);GO:0072341(modified amino acid binding);GO:0050667(homocysteine metabolic process);GO:0006526(arginine biosynthetic process);GO:0042311(vasodilation);GO:0004087(carbamoyl-phosphate synthase (ammonia) activity);GO:0004175(endopeptidase activity);GO:0005509(calcium ion binding);GO:0005543(phospholipid binding);GO:0016595(glutamate binding);GO:0032403(protein complex binding);GO:0001889(liver development);GO:0007494(midgut development);GO:0009636(response to toxic substance);GO:0010043(response to zinc ion);GO:0014075(response to amine);GO:0032094(response to food);GO:0033762(response to glucagon);GO:0034201(response to oleic acid);GO:0042493(response to drug);GO:0042594(response to starvation);GO:0043200(response to amino acid);GO:0044344(cellular response to fibroblast growth factor stimulus);GO:0046209(nitric oxide metabolic process);GO:0048545(response to steroid hormone);GO:0051384(response to glucocorticoid);GO:0051591(response to cAMP);GO:0055081(anion homeostasis);GO:0060416(response to growth hormone);GO:0070365(hepatocyte differentiation);GO:0070409(carbamoyl phosphate biosynthetic process);GO:0071320(cellular response to cAMP);GO:0071377(cellular response to glucagon stimulus);GO:0071400(cellular response to oleic acid);GO:0071548(response to dexamethasone);GO:1903718(cellular response to ammonia);GO:0005737(cytoplasm);GO:0005743(mitochondrial inner membrane);GO:0043234(protein complex)","00910(Nitrogen metabolism);00250(Alanine, aspartate and glutamate metabolism);00220(Arginine biosynthesis)","K01948","EC:6.3.4.16","carbamoyl-phosphate synthase 1 [Source:HGNC Symbol;Acc:HGNC:2323]",{"v":0.00508640808119494,"d":"0.01"},0,"inf","inf",1,1,"up","no"]
["MSTRG.5159","AC022898.1","ENST00000558630","NA","NA","NA","NA",null,0,{"v":0.0259969348268839,"d":"0.03"},"-inf","-inf",1,1,"down","no"]
["ENSG00000276966","HIST1H4E","ENST00000615164","GO:0005634(nucleus);GO:0003723(RNA binding);GO:0016020(membrane);GO:0003677(DNA binding);GO:0046982(protein heterodimerization activity);GO:0006334(nucleosome assembly);GO:0000786(nucleosome);GO:0005694(chromosome);GO:0005515(protein binding);GO:0006352(DNA-templated transcription, initiation);GO:0005576(extracellular region);GO:0005654(nucleoplasm);GO:0070062(extracellular exosome);GO:0044267(cellular protein metabolic process);GO:1902036(regulation of hematopoietic stem cell differentiation);GO:0043234(protein complex);GO:0000784(nuclear chromosome, telomeric region);GO:0034080(CENP-A containing nucleosome assembly);GO:0031012(extracellular matrix);GO:0045815(positive regulation of gene expression, epigenetic);GO:0019904(protein domain specific binding);GO:0042393(histone binding);GO:1904837(beta-catenin-TCF complex assembly);GO:0045652(regulation of megakaryocyte differentiation);GO:0006335(DNA replication-dependent nucleosome assembly);GO:0006336(DNA replication-independent nucleosome assembly);GO:0000228(nuclear chromosome);GO:0060964(regulation of gene silencing by miRNA);GO:0000183(chromatin silencing at rDNA);GO:0045814(negative regulation of gene expression, epigenetic);GO:0006303(double-strand break repair via nonhomologous end joining);GO:0051290(protein heterotetramerization);GO:0045653(negative regulation of megakaryocyte differentiation);GO:0016233(telomere capping);GO:0032200(telomere organization);GO:0000788(nuclear nucleosome)","05203(Viral carcinogenesis);05322(Systemic lupus erythematosus);05034(Alcoholism)","K11254","NA","histone cluster 1 H4 family member e [Source:HGNC Symbol;Acc:HGNC:4790]",{"v":0.035723,"d":"0.04"},0,"inf","inf",1,1,"up","no"]
["ENSG00000227488","GAGE12D","ENST00000405679","GO:0005515(protein binding)","NA","NA","NA","G antigen 12D [Source:HGNC Symbol;Acc:HGNC:31904]",0,0,1,0,1,1,"no","no"]
["ENSG00000255642","PABPC1P4","ENST00000539977","NA","NA","NA","NA","poly(A) binding protein cytoplasmic 1 pseudogene 4 [Source:HGNC Symbol;Acc:HGNC:8563]",0,0,1,0,1,1,"no","no"]
["ENSG00000228208","C1orf143","ENST00000491260","NA","NA","NA","NA","chromosome 1 open reading frame 143 [Source:HGNC Symbol;Acc:HGNC:32045]",0,0,1,0,1,1,"no","no"]
["ENSG00000153233","PTPRR","ENST00000283228;ENST00000551219;ENST00000547752","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005829(cytosol);GO:0016787(hydrolase activity);GO:0005886(plasma membrane);GO:0004725(protein tyrosine phosphatase activity);GO:0016791(phosphatase activity);GO:0006470(protein dephosphorylation);GO:0016311(dephosphorylation);GO:0035335(peptidyl-tyrosine dephosphorylation);GO:0030054(cell junction);GO:0004721(phosphoprotein phosphatase activity);GO:0005515(protein binding);GO:0048471(perinuclear region of cytoplasm);GO:0005615(extracellular space);GO:0019901(protein kinase binding);GO:0001701(in utero embryonic development);GO:0070373(negative regulation of ERK1 and ERK2 cascade);GO:0038128(ERBB2 signaling pathway);GO:0005001(transmembrane receptor protein tyrosine phosphatase activity);GO:0010633(negative regulation of epithelial cell migration);GO:0010633(negative regulation of epithelial cell migration)","04010(MAPK signaling pathway);04010(MAPK signaling pathway)","K04458","EC:3.1.3.48","protein tyrosine phosphatase, receptor type R [Source:HGNC Symbol;Acc:HGNC:9680]",{"v":0.0103303204978608,"d":"0.01"},0,"inf","inf",1,1,"up","no"]
["ENSG00000267507","AC010327.2","ENST00000587647","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000223885","FAM90A13P","ENST00000534703","NA","NA","NA","NA","family with sequence similarity 90 member A13, pseudogene [Source:HGNC Symbol;Acc:HGNC:32261]",0,{"v":0.004832,"d":"0.00"},"-inf","-inf",1,1,"down","no"]
["MSTRG.2328","AL133330.1","ENST00000510619","NA","NA","NA","NA",null,{"v":0.479044,"d":"0.48"},{"v":0.310678,"d":"0.31"},{"v":1.54193087376641,"d":"1.54"},{"v":0.624738089306243,"d":"0.62"},1,1,"up","no"]
["ENSG00000165125","TRPV6","ENST00000485138;ENST00000615386;ENST00000619250;ENST00000359396","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005216(ion channel activity);GO:0006811(ion transport);GO:0034220(ion transmembrane transport);GO:0070588(calcium ion transmembrane transport);GO:0006816(calcium ion transport);GO:0005262(calcium channel activity);GO:0006810(transport);GO:0055085(transmembrane transport);GO:0046872(metal ion binding);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0005516(calmodulin binding);GO:0005887(integral component of plasma membrane);GO:0070062(extracellular exosome);GO:0051592(response to calcium ion);GO:0055074(calcium ion homeostasis);GO:0098703(calcium ion import across plasma membrane);GO:0017158(regulation of calcium ion-dependent exocytosis);GO:0017158(regulation of calcium ion-dependent exocytosis)","04970(Salivary secretion);04978(Mineral absorption);04978(Mineral absorption)","K04975","NA","transient receptor potential cation channel subfamily V member 6 [Source:HGNC Symbol;Acc:HGNC:14006]",{"v":0.0161801175681342,"d":"0.02"},{"v":0.00894477031446541,"d":"0.01"},{"v":1.80889134089534,"d":"1.81"},{"v":0.855105748666925,"d":"0.86"},1,1,"up","no"]
["ENSG00000179954","SSC5D","ENST00000389623;ENST00000587166","GO:0016020(membrane);GO:0005044(scavenger receptor activity);GO:0006898(receptor-mediated endocytosis);GO:0005737(cytoplasm);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0043236(laminin binding);GO:0007275(multicellular organism development);GO:0005615(extracellular space);GO:0002376(immune system process);GO:0045087(innate immune response);GO:0001968(fibronectin binding);GO:0050840(extracellular matrix binding);GO:0042494(detection of bacterial lipoprotein);GO:2000483(negative regulation of interleukin-8 secretion);GO:0005622(intracellular);GO:0031012(extracellular matrix);GO:0006952(defense response);GO:0050829(defense response to Gram-negative bacterium);GO:0050830(defense response to Gram-positive bacterium);GO:2000482(regulation of interleukin-8 secretion);GO:2000482(regulation of interleukin-8 secretion)","NA","NA","NA","scavenger receptor cysteine rich family member with 5 domains [Source:HGNC Symbol;Acc:HGNC:26641]",{"v":0.000457075471698113,"d":"0.00"},{"v":0.00695814602132896,"d":"0.01"},{"v":0.0656892612338156,"d":"0.07"},{"v":-3.92819864922736,"d":"-3.93"},1,1,"down","no"]
["MSTRG.13022","TREML5P","ENST00000421694","NA","NA","NA","NA","triggering receptor expressed on myeloid cells like 5, pseudogene [Source:HGNC Symbol;Acc:HGNC:30808]",{"v":0.132517,"d":"0.13"},{"v":0.158965,"d":"0.16"},{"v":0.833623753656465,"d":"0.83"},{"v":-0.262531707872982,"d":"-0.26"},1,1,"down","no"]
["ENSG00000119547","ONECUT2","ENST00000491143;ENST00000481727","GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0006366(transcription from RNA polymerase II promoter);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0015629(actin cytoskeleton);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0030154(cell differentiation);GO:0001077(transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0009887(animal organ morphogenesis);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0001889(liver development);GO:0001952(regulation of cell-matrix adhesion);GO:0002064(epithelial cell development);GO:0009653(anatomical structure morphogenesis);GO:0030335(positive regulation of cell migration);GO:0030512(negative regulation of transforming growth factor beta receptor signaling pathway);GO:0031016(pancreas development);GO:0031018(endocrine pancreas development);GO:0045165(cell fate commitment);GO:0048935(peripheral nervous system neuron development);GO:0060271(cilium assembly);GO:0060271(cilium assembly)","NA","NA","NA","one cut homeobox 2 [Source:HGNC Symbol;Acc:HGNC:8139]",0,0,1,0,1,1,"no","no"]
["ENSG00000176571","CNBD1","ENST00000518476","NA","NA","NA","NA","cyclic nucleotide binding domain containing 1 [Source:HGNC Symbol;Acc:HGNC:26663]",0,0,1,0,1,1,"no","no"]
["ENSG00000142583","SLC2A5","ENST00000377424;ENST00000377414;ENST00000486632","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005215(transporter activity);GO:0055085(transmembrane transport);GO:0005886(plasma membrane);GO:0022857(transmembrane transporter activity);GO:0022891(substrate-specific transmembrane transporter activity);GO:0008643(carbohydrate transport);GO:1904659(glucose transmembrane transport);GO:0005887(integral component of plasma membrane);GO:0005353(fructose transmembrane transporter activity);GO:0015755(fructose transport);GO:0070062(extracellular exosome);GO:0042383(sarcolemma);GO:0043312(neutrophil degranulation);GO:0035579(specific granule membrane);GO:0016324(apical plasma membrane);GO:0005975(carbohydrate metabolic process);GO:0005355(glucose transmembrane transporter activity);GO:0015758(glucose transport);GO:0106001(intestinal hexose absorption);GO:0071332(cellular response to fructose stimulus);GO:0070061(fructose binding);GO:0003044(regulation of systemic arterial blood pressure mediated by a chemical signal);GO:0009750(response to fructose);GO:1990539(fructose import across plasma membrane);GO:1990539(fructose import across plasma membrane)","04973(Carbohydrate digestion and absorption);04973(Carbohydrate digestion and absorption)","K08143","NA","solute carrier family 2 member 5 [Source:HGNC Symbol;Acc:HGNC:11010]",{"v":0.157076444046018,"d":"0.16"},{"v":0.106414905423577,"d":"0.11"},{"v":1.47607558753904,"d":"1.48"},{"v":0.561766601463043,"d":"0.56"},1,1,"up","no"]
["ENSG00000249244","AC110373.1","ENST00000505994","NA","NA","NA","NA",null,{"v":0.030311,"d":"0.03"},{"v":0.01452,"d":"0.01"},{"v":2.08753443526171,"d":"2.09"},{"v":1.06179999599222,"d":"1.06"},1,1,"up","no"]
["MSTRG.6771","AC006441.3","ENST00000580121","NA","NA","NA","NA",null,{"v":0.004448,"d":"0.00"},0,"inf","inf",1,1,"up","no"]
["ENSG00000240086","AC128689.1","ENST00000459861;ENST00000473001","NA","NA","NA","NA",null,{"v":0.0193429479472141,"d":"0.02"},{"v":0.0373107228739003,"d":"0.04"},{"v":0.51842865689276,"d":"0.52"},{"v":-0.947782627408653,"d":"-0.95"},1,1,"down","no"]
["MSTRG.10585","FP325331.1","ENST00000639527;ENST00000623531","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000131142","CCL25","ENST00000315626","GO:0005576(extracellular region);GO:0006955(immune response);GO:0007186(G-protein coupled receptor signaling pathway);GO:0005125(cytokine activity);GO:0005615(extracellular space);GO:0008009(chemokine activity);GO:0006935(chemotaxis);GO:0006954(inflammatory response);GO:0002548(monocyte chemotaxis);GO:0030593(neutrophil chemotaxis);GO:0043547(positive regulation of GTPase activity);GO:0048247(lymphocyte chemotaxis);GO:0070098(chemokine-mediated signaling pathway);GO:0070374(positive regulation of ERK1 and ERK2 cascade);GO:0071346(cellular response to interferon-gamma);GO:0071347(cellular response to interleukin-1);GO:0071356(cellular response to tumor necrosis factor);GO:0007166(cell surface receptor signaling pathway);GO:0042379(chemokine receptor binding);GO:0001954(positive regulation of cell-matrix adhesion);GO:0060326(cell chemotaxis);GO:1903237(negative regulation of leukocyte tethering or rolling);GO:0005179(hormone activity);GO:0031735(CCR10 chemokine receptor binding);GO:0050900(leukocyte migration)","04060(Cytokine-cytokine receptor interaction);04672(Intestinal immune network for IgA production);04062(Chemokine signaling pathway)","NA","NA","C-C motif chemokine ligand 25 [Source:HGNC Symbol;Acc:HGNC:10624]",0,0,1,0,1,1,"no","no"]
["ENSG00000183250","LINC01547","ENST00000615847;ENST00000397841;ENST00000330551","NA","NA","NA","NA","long intergenic non-protein coding RNA 1547 [Source:HGNC Symbol;Acc:HGNC:15707]",{"v":0.569040397966867,"d":"0.57"},{"v":0.175778902861446,"d":"0.18"},{"v":3.23725082307176,"d":"3.24"},{"v":1.69476915028074,"d":"1.69"},1,1,"up","no"]
["ENSG00000152592","DMP1","ENST00000339673","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005576(extracellular region);GO:0005578(proteinaceous extracellular matrix);GO:0001503(ossification);GO:0030198(extracellular matrix organization);GO:0031214(biomineral tissue development);GO:0044267(cellular protein metabolic process);GO:0043687(post-translational protein modification);GO:0005788(endoplasmic reticulum lumen);GO:0005509(calcium ion binding);GO:0005178(integrin binding);GO:0050840(extracellular matrix binding);GO:0010811(positive regulation of cell-substrate adhesion);GO:0070173(regulation of enamel mineralization)","NA","NA","NA","dentin matrix acidic phosphoprotein 1 [Source:HGNC Symbol;Acc:HGNC:2932]",0,0,1,0,1,1,"no","no"]
["MSTRG.11709","TECRP1","ENST00000513307","NA","NA","NA","NA","trans-2,3-enoyl-CoA reductase pseudogene 1 [Source:HGNC Symbol;Acc:HGNC:44050]",0,{"v":0.777472,"d":"0.78"},"-inf","-inf",1,1,"down","no"]
["MSTRG.6356","AC004771.1","ENST00000438266","NA","NA","NA","NA",null,{"v":0.233043,"d":"0.23"},{"v":0.087293,"d":"0.09"},{"v":2.66966423424559,"d":"2.67"},{"v":1.41665830444104,"d":"1.42"},1,1,"up","no"]
["ENSG00000279026","AC005225.5","ENST00000623547","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000237788","AL162615.1","ENST00000429893","NA","NA","NA","NA",null,{"v":0.032135,"d":"0.03"},0,"inf","inf",1,1,"up","no"]
["ENSG00000250539","KRT8P33","ENST00000508125","NA","NA","NA","NA","keratin 8 pseudogene 33 [Source:HGNC Symbol;Acc:HGNC:39867]",0,{"v":0.142463,"d":"0.14"},"-inf","-inf",1,1,"down","no"]
["ENSG00000241007","SEPT7P6","ENST00000469999","NA","NA","NA","NA","septin 7 pseudogene 6 [Source:HGNC Symbol;Acc:HGNC:38042]",0,0,1,0,1,1,"no","no"]
["ENSG00000261279","ULK4P1","ENST00000564495;ENST00000565174","NA","NA","NA","NA","ULK4 pseudogene 1 [Source:HGNC Symbol;Acc:HGNC:15775]",{"v":0.0172224576170717,"d":"0.02"},0,"inf","inf",1,1,"up","no"]
["ENSG00000173212","MAB21L3","ENST00000369500","GO:0005515(protein binding)","NA","NA","NA","mab-21 like 3 [Source:HGNC Symbol;Acc:HGNC:26787]",0,{"v":0.0156303037469287,"d":"0.02"},"-inf","-inf",1,1,"down","no"]
["ENSG00000263167","AC115099.1","ENST00000570413","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000258927","AL133467.2","ENST00000555032","NA","NA","NA","NA",null,0,{"v":0.011012,"d":"0.01"},"-inf","-inf",1,1,"down","no"]
["MSTRG.8225","AC005757.1","ENST00000591432","NA","NA","NA","NA",null,{"v":0.073786,"d":"0.07"},0,"inf","inf",1,1,"up","no"]
["ENSG00000058335","RASGRF1","ENST00000419573;ENST00000560286","GO:0007264(small GTPase mediated signal transduction);GO:0035556(intracellular signal transduction);GO:0005886(plasma membrane);GO:0005089(Rho guanyl-nucleotide exchange factor activity);GO:0035023(regulation of Rho protein signal transduction);GO:0005085(guanyl-nucleotide exchange factor activity);GO:0046578(regulation of Ras protein signal transduction);GO:0000165(MAPK cascade);GO:0007616(long-term memory);GO:0043005(neuron projection);GO:0005829(cytosol);GO:0007165(signal transduction);GO:0005088(Ras guanyl-nucleotide exchange factor activity);GO:0048167(regulation of synaptic plasticity);GO:0046579(positive regulation of Ras protein signal transduction);GO:0043547(positive regulation of GTPase activity);GO:0030426(growth cone);GO:0031175(neuron projection development);GO:0035020(regulation of Rac protein signal transduction);GO:0090630(activation of GTPase activity);GO:0035254(glutamate receptor binding);GO:0008283(cell proliferation);GO:0048168(regulation of neuronal synaptic plasticity);GO:2000310(regulation of NMDA receptor activity);GO:2000310(regulation of NMDA receptor activity)","04014(Ras signaling pathway);04010(MAPK signaling pathway);04510(Focal adhesion);04510(Focal adhesion)","K04349","NA","Ras protein specific guanine nucleotide releasing factor 1 [Source:HGNC Symbol;Acc:HGNC:9875]",{"v":0.0333097940376674,"d":"0.03"},{"v":0.00448041011179374,"d":"0.00"},{"v":7.43454130459762,"d":"7.43"},{"v":2.89424373380474,"d":"2.89"},1,1,"up","no"]
["MSTRG.4727","AHNAK2","ENST00000555122","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0030659(cytoplasmic vesicle membrane);GO:0005515(protein binding);GO:0042383(sarcolemma);GO:0030315(T-tubule);GO:0030018(Z disc);GO:0043034(costamere)","NA","NA","NA","AHNAK nucleoprotein 2 [Source:HGNC Symbol;Acc:HGNC:20125]",{"v":0.0438072779819935,"d":"0.04"},{"v":0.0132333162857599,"d":"0.01"},{"v":3.3103779155595,"d":"3.31"},{"v":1.72699592572771,"d":"1.73"},1,1,"up","no"]
["ENSG00000136011","STAB2","ENST00000388887;ENST00000552777","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005829(cytosol);GO:0005509(calcium ion binding);GO:0007155(cell adhesion);GO:0005886(plasma membrane);GO:0055114(oxidation-reduction process);GO:0005515(protein binding);GO:0005540(hyaluronic acid binding);GO:0006898(receptor-mediated endocytosis);GO:0042742(defense response to bacterium);GO:0005887(integral component of plasma membrane);GO:0006897(endocytosis);GO:0005044(scavenger receptor activity);GO:0030666(endocytic vesicle membrane);GO:0001525(angiogenesis);GO:0009897(external side of plasma membrane);GO:0030214(hyaluronan catabolic process);GO:0010468(regulation of gene expression);GO:0030193(regulation of blood coagulation);GO:0015035(protein disulfide oxidoreductase activity);GO:0030169(low-density lipoprotein particle binding);GO:0005041(low-density lipoprotein receptor activity);GO:0005041(low-density lipoprotein receptor activity)","NA","NA","NA","stabilin 2 [Source:HGNC Symbol;Acc:HGNC:18629]",0,0,1,0,1,1,"no","no"]
["ENSG00000229670","PKP4P1","ENST00000426801","NA","NA","NA","NA","plakophilin 4 pseudogene 1 [Source:HGNC Symbol;Acc:HGNC:42661]",0,0,1,0,1,1,"no","no"]
["ENSG00000267521","AC016168.1","ENST00000591422","NA","NA","NA","NA",null,0,{"v":0.105809,"d":"0.11"},"-inf","-inf",1,1,"down","no"]
["ENSG00000214237","MINDY4B","ENST00000465419","NA","NA","NA","NA","MINDY family member 4B [Source:HGNC Symbol;Acc:HGNC:35475]",{"v":0.00983439323843416,"d":"0.01"},{"v":0.015724037366548,"d":"0.02"},{"v":0.625436903333509,"d":"0.63"},{"v":-0.677063748209126,"d":"-0.68"},1,1,"down","no"]
["ENSG00000227176","AC092641.1","ENST00000440229","NA","NA","NA","NA",null,{"v":0.053517,"d":"0.05"},0,"inf","inf",1,1,"up","no"]
["ENSG00000253649","PRSS51","ENST00000636217;ENST00000523024","GO:0006508(proteolysis);GO:0004252(serine-type endopeptidase activity);GO:0004252(serine-type endopeptidase activity)","NA","NA","NA","protease, serine 51 [Source:HGNC Symbol;Acc:HGNC:37321]",{"v":0.00767235375494071,"d":"0.01"},{"v":0.0158192822793149,"d":"0.02"},{"v":0.485000116912572,"d":"0.49"},{"v":-1.04394299981612,"d":"-1.04"},1,1,"down","no"]
["MSTRG.6780","KRT8P34","ENST00000577607","NA","NA","NA","NA","keratin 8 pseudogene 34 [Source:HGNC Symbol;Acc:HGNC:39868]",{"v":0.050881,"d":"0.05"},0,"inf","inf",1,1,"up","no"]
["ENSG00000226002","GTF2IP14","ENST00000441415","NA","NA","NA","NA","general transcription factor IIi pseudogene 14 [Source:HGNC Symbol;Acc:HGNC:51726]",{"v":0.039621,"d":"0.04"},{"v":0.037959,"d":"0.04"},{"v":1.04378408282621,"d":"1.04"},{"v":0.0618233068767921,"d":"0.06"},1,1,"up","no"]
["MSTRG.6705","AC015911.7","ENST00000587542","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000225960","AL441989.1","ENST00000454204","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000163995","ABLIM2","ENST00000514025;ENST00000428004;ENST00000407564;ENST00000512594;ENST00000504172;ENST00000361737","GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0003779(actin binding);GO:0006351(transcription, DNA-templated);GO:0030036(actin cytoskeleton organization);GO:0007010(cytoskeleton organization);GO:0015629(actin cytoskeleton);GO:0015629(actin cytoskeleton)","04360(Axon guidance);04360(Axon guidance)","K07520","NA","actin binding LIM protein family member 2 [Source:HGNC Symbol;Acc:HGNC:19195]",{"v":0.148116878988263,"d":"0.15"},{"v":0.100959129773516,"d":"0.10"},{"v":1.46709742170458,"d":"1.47"},{"v":0.552964675471699,"d":"0.55"},1,1,"up","no"]
["ENSG00000232628","AC092809.2","ENST00000453760;ENST00000436706","NA","NA","NA","NA",null,{"v":0.0354707328482328,"d":"0.04"},0,"inf","inf",1,1,"up","no"]
["MSTRG.3907","PSPC1P2","ENST00000455130","NA","NA","NA","NA","paraspeckle component 1 pseudogene 2 [Source:HGNC Symbol;Acc:HGNC:42643]",0,0,1,0,1,1,"no","no"]
["ENSG00000102053","ZC3H12B","ENST00000617377;ENST00000338957","GO:0046872(metal ion binding);GO:0016787(hydrolase activity);GO:0090305(nucleic acid phosphodiester bond hydrolysis);GO:0004519(endonuclease activity);GO:0004518(nuclease activity);GO:0004518(nuclease activity)","NA","NA","NA","zinc finger CCCH-type containing 12B [Source:HGNC Symbol;Acc:HGNC:17407]",{"v":0.16095270507089,"d":"0.16"},{"v":0.0939764416911483,"d":"0.09"},{"v":1.71269205531167,"d":"1.71"},{"v":0.776265775932962,"d":"0.78"},1,1,"up","no"]
["MSTRG.11911","GK3P","ENST00000505354","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0016773(phosphotransferase activity, alcohol group as acceptor);GO:0005975(carbohydrate metabolic process);GO:0005739(mitochondrion);GO:0006072(glycerol-3-phosphate metabolic process);GO:0005741(mitochondrial outer membrane);GO:0004370(glycerol kinase activity);GO:0006071(glycerol metabolic process);GO:0019563(glycerol catabolic process);GO:0006641(triglyceride metabolic process);GO:0046167(glycerol-3-phosphate biosynthetic process)","NA","NA","NA","glycerol kinase 3 pseudogene [Source:HGNC Symbol;Acc:HGNC:4292]",{"v":0.182642,"d":"0.18"},{"v":0.32153,"d":"0.32"},{"v":0.568040307280814,"d":"0.57"},{"v":-0.81593479006773,"d":"-0.82"},1,1,"down","no"]
["ENSG00000264745","TTC39C-AS1","ENST00000579713","NA","NA","NA","NA","TTC39C antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:51321]",{"v":0.564151,"d":"0.56"},{"v":0.584065,"d":"0.58"},{"v":0.96590447980961,"d":"0.97"},{"v":-0.0500475697173422,"d":"-0.05"},1,1,"down","no"]
["ENSG00000236779","AL512306.1","ENST00000432698","NA","NA","NA","NA",null,{"v":0.062227,"d":"0.06"},0,"inf","inf",1,1,"up","no"]
["MSTRG.3151","PZP","ENST00000539983;ENST00000261336","GO:0005615(extracellular space);GO:0005576(extracellular region);GO:0010951(negative regulation of endopeptidase activity);GO:0030414(peptidase inhibitor activity);GO:0010466(negative regulation of peptidase activity);GO:0004866(endopeptidase inhibitor activity);GO:0070062(extracellular exosome);GO:0072562(blood microparticle);GO:0004867(serine-type endopeptidase inhibitor activity);GO:0007565(female pregnancy);GO:0007565(female pregnancy)","NA","NA","NA","PZP, alpha-2-macroglobulin like [Source:HGNC Symbol;Acc:HGNC:9750]",{"v":0.00684133772281998,"d":"0.01"},{"v":0.0125262887425727,"d":"0.01"},{"v":0.546158392434987,"d":"0.55"},{"v":-0.872608684325258,"d":"-0.87"},1,1,"down","no"]
["ENSG00000189292","ALKAL2","ENST00000403610;ENST00000463919","GO:0005515(protein binding);GO:0005576(extracellular region);GO:0061098(positive regulation of protein tyrosine kinase activity);GO:0030298(receptor signaling protein tyrosine kinase activator activity);GO:0030971(receptor tyrosine kinase binding);GO:0070374(positive regulation of ERK1 and ERK2 cascade);GO:0010976(positive regulation of neuron projection development);GO:0070378(positive regulation of ERK5 cascade);GO:0070378(positive regulation of ERK5 cascade)","NA","NA","NA","ALK and LTK ligand 2 [Source:HGNC Symbol;Acc:HGNC:27683]",{"v":0.0540887539936102,"d":"0.05"},{"v":0.0232275540848927,"d":"0.02"},{"v":2.32864613277511,"d":"2.33"},{"v":1.21949142045102,"d":"1.22"},1,1,"up","no"]
["ENSG00000228222","AC073050.1","ENST00000442316","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["MSTRG.9391","AC009226.1","ENST00000418850;ENST00000412387","NA","NA","NA","NA",null,{"v":0.0206852982866044,"d":"0.02"},{"v":0.0594531308411215,"d":"0.06"},{"v":0.347926139363163,"d":"0.35"},{"v":-1.52314702353815,"d":"-1.52"},1,1,"down","no"]
["ENSG00000180043","FAM71E2","ENST00000424985","GO:0005634(nucleus)","NA","NA","NA","family with sequence similarity 71 member E2 [Source:HGNC Symbol;Acc:HGNC:25278]",0,0,1,0,1,1,"no","no"]
["MSTRG.5827","AC012645.4","ENST00000610691","NA","NA","NA","NA",null,0,{"v":0.454882,"d":"0.45"},"-inf","-inf",1,1,"down","no"]
["ENSG00000259009","TPRX2P","ENST00000535362","NA","NA","NA","NA","tetrapeptide repeat homeobox 2, pseudogene [Source:HGNC Symbol;Acc:HGNC:32175]",0,0,1,0,1,1,"no","no"]
["MSTRG.14236","AC107959.1","ENST00000523884;ENST00000502083","NA","NA","NA","NA",null,{"v":0.495364921516755,"d":"0.50"},{"v":0.294259290123457,"d":"0.29"},{"v":1.6834300161226,"d":"1.68"},{"v":0.751403746415622,"d":"0.75"},1,1,"up","no"]
["ENSG00000224883","Z99716.1","ENST00000424613","NA","NA","NA","NA",null,{"v":0.06152,"d":"0.06"},0,"inf","inf",1,1,"up","no"]
["ENSG00000258556","LINC02322","ENST00000554773","NA","NA","NA","NA","long intergenic non-protein coding RNA 2322 [Source:HGNC Symbol;Acc:HGNC:53241]",0,0,1,0,1,1,"no","no"]
["MSTRG.12343","AC026691.1","ENST00000602502","NA","NA","NA","NA",null,{"v":0.052672,"d":"0.05"},0,"inf","inf",1,1,"up","no"]
["ENSG00000151322","NPAS3","ENST00000550662;ENST00000346562;ENST00000549770","GO:0005634(nucleus);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0046983(protein dimerization activity);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0045893(positive regulation of transcription, DNA-templated);GO:0000981(RNA polymerase II transcription factor activity, sequence-specific DNA binding);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0032502(developmental process);GO:0032502(developmental process)","NA","NA","NA","neuronal PAS domain protein 3 [Source:HGNC Symbol;Acc:HGNC:19311]",0,0,1,0,1,1,"no","no"]
["ENSG00000275374","AC113385.3","ENST00000621479","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000151640","DPYSL4","ENST00000471544;ENST00000338492;ENST00000493927","GO:0005737(cytoplasm);GO:0016787(hydrolase activity);GO:0005515(protein binding);GO:0016810(hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds);GO:0005829(cytosol);GO:0007399(nervous system development);GO:0031005(filamin binding);GO:0070997(neuron death);GO:0097485(neuron projection guidance);GO:0097485(neuron projection guidance)","NA","NA","NA","dihydropyrimidinase like 4 [Source:HGNC Symbol;Acc:HGNC:3016]",{"v":0.103287307304786,"d":"0.10"},{"v":0.0957719178211587,"d":"0.10"},{"v":1.07847174468889,"d":"1.08"},{"v":0.108988379251073,"d":"0.11"},1,1,"up","no"]
["MSTRG.13260","FAM184A","ENST00000338891;ENST00000475529;ENST00000482219;ENST00000522284","GO:0005615(extracellular space);GO:0003674(molecular_function);GO:0008150(biological_process);GO:0005515(protein binding);GO:0005515(protein binding)","NA","NA","NA","family with sequence similarity 184 member A [Source:HGNC Symbol;Acc:HGNC:20991]",{"v":0.13074383301245,"d":"0.13"},{"v":0.0709019351816198,"d":"0.07"},{"v":1.84400937262913,"d":"1.84"},{"v":0.882845988636666,"d":"0.88"},1,1,"up","no"]
["ENSG00000164299","SPZ1","ENST00000296739","GO:0005634(nucleus);GO:0006355(regulation of transcription, DNA-templated);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0005737(cytoplasm);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0005515(protein binding)","NA","NA","NA","spermatogenic leucine zipper 1 [Source:HGNC Symbol;Acc:HGNC:30721]",0,0,1,0,1,1,"no","no"]
["ENSG00000278023","RDM1","ENST00000620284;ENST00000619262","GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005730(nucleolus);GO:0005829(cytosol);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0016605(PML body);GO:0015030(Cajal body);GO:0006281(DNA repair);GO:0006310(DNA recombination);GO:0006310(DNA recombination)","NA","NA","NA","RAD52 motif containing 1 [Source:HGNC Symbol;Acc:HGNC:19950]",{"v":0.264552392405063,"d":"0.26"},{"v":0.0625044951898734,"d":"0.06"},{"v":4.23253386178734,"d":"4.23"},{"v":2.08152161024431,"d":"2.08"},1,1,"up","no"]
["ENSG00000135643","KCNMB4","ENST00000258111;ENST00000531884","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0006811(ion transport);GO:0006813(potassium ion transport);GO:0071805(potassium ion transmembrane transport);GO:0065009(regulation of molecular function);GO:0005886(plasma membrane);GO:0015269(calcium-activated potassium channel activity);GO:0005887(integral component of plasma membrane);GO:0005515(protein binding);GO:0007268(chemical synaptic transmission);GO:0019229(regulation of vasoconstriction);GO:0008076(voltage-gated potassium channel complex);GO:0019228(neuronal action potential);GO:0005513(detection of calcium ion);GO:0046928(regulation of neurotransmitter secretion);GO:0001508(action potential);GO:0015459(potassium channel regulator activity);GO:0015459(potassium channel regulator activity)","04022(cGMP - PKG signaling pathway);04911(Insulin secretion);04270(Vascular smooth muscle contraction);04270(Vascular smooth muscle contraction)","K04941","NA","potassium calcium-activated channel subfamily M regulatory beta subunit 4 [Source:HGNC Symbol;Acc:HGNC:6289]",{"v":0.13085573266311,"d":"0.13"},{"v":0.135705153262208,"d":"0.14"},{"v":0.964265022495292,"d":"0.96"},{"v":-0.0524983777972506,"d":"-0.05"},1,1,"down","no"]
["ENSG00000223569","USP17L15","ENST00000621432","GO:0005634(nucleus);GO:0016579(protein deubiquitination);GO:0016787(hydrolase activity);GO:0005783(endoplasmic reticulum);GO:0008233(peptidase activity);GO:0008234(cysteine-type peptidase activity);GO:0006508(proteolysis);GO:0006511(ubiquitin-dependent protein catabolic process);GO:0036459(thiol-dependent ubiquitinyl hydrolase activity)","NA","NA","NA","ubiquitin specific peptidase 17-like family member 15 [Source:HGNC Symbol;Acc:HGNC:44443]",0,0,1,0,1,1,"no","no"]
["ENSG00000175785","PRIMA1","ENST00000393143","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005886(plasma membrane);GO:0030054(cell junction);GO:0045202(synapse);GO:0042135(neurotransmitter catabolic process)","NA","NA","NA","proline rich membrane anchor 1 [Source:HGNC Symbol;Acc:HGNC:18319]",0,0,1,0,1,1,"no","no"]
["ENSG00000179919","OR10A7","ENST00000326258","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0004930(G-protein coupled receptor activity);GO:0007186(G-protein coupled receptor signaling pathway);GO:0005886(plasma membrane);GO:0004871(signal transducer activity);GO:0007165(signal transduction);GO:0004984(olfactory receptor activity);GO:0007608(sensory perception of smell);GO:0050896(response to stimulus);GO:0050911(detection of chemical stimulus involved in sensory perception of smell)","04740(Olfactory transduction)","K04257","NA","olfactory receptor family 10 subfamily A member 7 [Source:HGNC Symbol;Acc:HGNC:15329]",0,0,1,0,1,1,"no","no"]
["MSTRG.6090","CLEC18C","ENST00000569268;ENST00000569347;ENST00000618957;ENST00000569201","GO:0030246(carbohydrate binding);GO:0005794(Golgi apparatus);GO:0005783(endoplasmic reticulum);GO:0005576(extracellular region);GO:0005768(endosome);GO:0030247(polysaccharide binding);GO:0030247(polysaccharide binding)","NA","NA","NA","C-type lectin domain family 18 member C [Source:HGNC Symbol;Acc:HGNC:28538]",{"v":0.040491915815284,"d":"0.04"},{"v":0.0318253810788721,"d":"0.03"},{"v":1.27231519129131,"d":"1.27"},{"v":0.347456114477328,"d":"0.35"},1,1,"up","no"]
["ENSG00000237161","AC068446.1","ENST00000556425","NA","NA","NA","NA",null,{"v":0.662069,"d":"0.66"},0,"inf","inf",1,1,"up","no"]
["ENSG00000254966","AC103974.1","ENST00000527285","NA","NA","NA","NA",null,{"v":0.178679,"d":"0.18"},0,"inf","inf",1,1,"up","no"]
["ENSG00000234655","OR7E155P","ENST00000412208","NA","NA","NA","NA","olfactory receptor family 7 subfamily E member 155 pseudogene [Source:HGNC Symbol;Acc:HGNC:31310]",0,0,1,0,1,1,"no","no"]
["ENSG00000242715","CCDC169","ENST00000379864","NA","NA","NA","NA","coiled-coil domain containing 169 [Source:HGNC Symbol;Acc:HGNC:34361]",{"v":0.00601126264569424,"d":"0.01"},{"v":0.00575902772434084,"d":"0.01"},{"v":1.0437981779958,"d":"1.04"},{"v":0.0618427887737667,"d":"0.06"},1,1,"up","no"]
["ENSG00000270601","PRAMEF5","ENST00000622421","GO:0043066(negative regulation of apoptotic process);GO:0008284(positive regulation of cell proliferation);GO:0045596(negative regulation of cell differentiation);GO:0045892(negative regulation of transcription, DNA-templated)","NA","NA","NA","PRAME family member 5 [Source:HGNC Symbol;Acc:HGNC:27995]",0,0,1,0,1,1,"no","no"]
["ENSG00000112559","MDFI","ENST00000230321","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005515(protein binding);GO:0007275(multicellular organism development);GO:0030154(cell differentiation);GO:0042802(identical protein binding);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0008134(transcription factor binding);GO:0030178(negative regulation of Wnt signaling pathway);GO:0045892(negative regulation of transcription, DNA-templated);GO:0042994(cytoplasmic sequestering of transcription factor);GO:0043392(negative regulation of DNA binding);GO:0009950(dorsal/ventral axis specification);GO:0009790(embryo development);GO:0048704(embryonic skeletal system morphogenesis);GO:0060707(trophoblast giant cell differentiation)","NA","NA","NA","MyoD family inhibitor [Source:HGNC Symbol;Acc:HGNC:6967]",0,0,1,0,1,1,"no","no"]
["ENSG00000243792","OR7E89P","ENST00000411729","NA","NA","NA","NA","olfactory receptor family 7 subfamily E member 89 pseudogene [Source:HGNC Symbol;Acc:HGNC:14730]",{"v":0.057561,"d":"0.06"},0,"inf","inf",1,1,"up","no"]
["ENSG00000230806","SRGAP2-AS1","ENST00000437515","NA","NA","NA","NA","SRGAP2 antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:40902]",0,0,1,0,1,1,"no","no"]
["ENSG00000267626","AC002115.1","ENST00000589603","NA","NA","NA","NA",null,{"v":0.044902,"d":"0.04"},0,"inf","inf",1,1,"up","no"]
["MSTRG.6194","AC040169.1","ENST00000565382","NA","NA","NA","NA",null,{"v":0.101957,"d":"0.10"},{"v":0.391371,"d":"0.39"},{"v":0.260512403831658,"d":"0.26"},{"v":-1.94057602940701,"d":"-1.94"},1,1,"down","no"]
["ENSG00000270578","AP000787.2","ENST00000604432","NA","NA","NA","NA",null,{"v":0.187042,"d":"0.19"},0,"inf","inf",1,1,"up","no"]
["ENSG00000226308","AL122058.1","ENST00000412321","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000154240","CEP112","ENST00000392769;ENST00000580624","GO:0005737(cytoplasm);GO:0005856(cytoskeleton);GO:0005813(centrosome);GO:0005815(microtubule organizing center);GO:0097120(receptor localization to synapse);GO:0005886(plasma membrane);GO:0060077(inhibitory synapse);GO:0060077(inhibitory synapse)","NA","NA","NA","centrosomal protein 112 [Source:HGNC Symbol;Acc:HGNC:28514]",{"v":0.0505786630143967,"d":"0.05"},{"v":0.0259139585934514,"d":"0.03"},{"v":1.95179222935002,"d":"1.95"},{"v":0.964799484437604,"d":"0.96"},1,1,"up","no"]
["ENSG00000229847","EMX2OS","ENST00000551288;ENST00000423419","NA","NA","NA","NA","EMX2 opposite strand/antisense RNA [Source:HGNC Symbol;Acc:HGNC:18511]",{"v":0.00295275611967362,"d":"0.00"},0,"inf","inf",1,1,"up","no"]
["ENSG00000232098","AC012313.1","ENST00000597980;ENST00000593393","NA","NA","NA","NA",null,{"v":0.0632858472344162,"d":"0.06"},{"v":0.117867737196371,"d":"0.12"},{"v":0.536922560318437,"d":"0.54"},{"v":-0.897214069806886,"d":"-0.90"},1,1,"down","no"]
["ENSG00000283164","AC012507.4","ENST00000637275","NA","NA","NA","NA",null,{"v":0.524888,"d":"0.52"},{"v":0.252272,"d":"0.25"},{"v":2.08064311536754,"d":"2.08"},{"v":1.05702952641673,"d":"1.06"},1,1,"up","no"]
["ENSG00000250536","ABHD17AP3","ENST00000503096","NA","NA","NA","NA","abhydrolase domain containing 17A pseudogene 3 [Source:HGNC Symbol;Acc:HGNC:34041]",0,{"v":0.079145,"d":"0.08"},"-inf","-inf",1,1,"down","no"]
["ENSG00000165105","RASEF","ENST00000376447","GO:0005737(cytoplasm);GO:0005525(GTP binding);GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0005509(calcium ion binding);GO:0003924(GTPase activity);GO:0048471(perinuclear region of cytoplasm)","NA","NA","NA","RAS and EF-hand domain containing [Source:HGNC Symbol;Acc:HGNC:26464]",0,{"v":0.00765410618138066,"d":"0.01"},"-inf","-inf",1,1,"down","no"]
["ENSG00000279036","AC015656.1","ENST00000624209","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000171346","KRT15","ENST00000254043","GO:0005634(nucleus);GO:0005198(structural molecule activity);GO:0005515(protein binding);GO:0007010(cytoskeleton organization);GO:0005882(intermediate filament);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0031424(keratinization);GO:0005200(structural constituent of cytoskeleton);GO:0097110(scaffold protein binding);GO:0008544(epidermis development);GO:0070268(cornification)","NA","NA","NA","keratin 15 [Source:HGNC Symbol;Acc:HGNC:6421]",0,0,1,0,1,1,"no","no"]
["MSTRG.12839","AL645933.2","ENST00000606743","NA","NA","NA","NA",null,0,{"v":2.008718,"d":"2.01"},"-inf","-inf",1,1,"down","no"]
["ENSG00000282511","CLUHP10","ENST00000631979","NA","NA","NA","NA","clustered mitochondria homolog pseudogene 10 [Source:HGNC Symbol;Acc:HGNC:51574]",0,0,1,0,1,1,"no","no"]
["ENSG00000256913","AC005840.4","ENST00000541242","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["MSTRG.4312","AL445363.2","ENST00000554608","NA","NA","NA","NA",null,{"v":0.00224304221635884,"d":"0.00"},0,"inf","inf",1,1,"up","no"]
["ENSG00000147144","CCDC120","ENST00000597275;ENST00000482476;ENST00000536628;ENST00000606812;ENST00000620388","GO:0005737(cytoplasm);GO:0042995(cell projection);GO:0005515(protein binding);GO:0007275(multicellular organism development);GO:0005768(endosome);GO:0030426(growth cone);GO:0030426(growth cone)","NA","NA","NA","coiled-coil domain containing 120 [Source:HGNC Symbol;Acc:HGNC:28910]",{"v":0.346179284317413,"d":"0.35"},{"v":0.0511128653629184,"d":"0.05"},{"v":6.77284049445134,"d":"6.77"},{"v":2.7597610195913,"d":"2.76"},1,1,"up","no"]
["ENSG00000273148","AL035563.1","ENST00000609087","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["MSTRG.2458","AP001363.1","ENST00000544108","NA","NA","NA","NA",null,{"v":0.221846,"d":"0.22"},{"v":0.20873,"d":"0.21"},{"v":1.06283715805107,"d":"1.06"},{"v":0.0879205721571871,"d":"0.09"},1,1,"up","no"]
["ENSG00000131831","RAI2","ENST00000360011;ENST00000451717;ENST00000545871","GO:0005515(protein binding);GO:0003674(molecular_function);GO:0005575(cellular_component);GO:0009790(embryo development);GO:0009790(embryo development)","NA","NA","NA","retinoic acid induced 2 [Source:HGNC Symbol;Acc:HGNC:9835]",{"v":0.291770060259344,"d":"0.29"},0,"inf","inf",1,1,"up","no"]
["MSTRG.1039","MTX1P1","MSTRG.1039.1","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["MSTRG.8515","AC092687.3","ENST00000606907","NA","NA","NA","NA",null,{"v":0.128614,"d":"0.13"},0,"inf","inf",1,1,"up","no"]
["ENSG00000255495","AC145124.1","ENST00000528514","NA","NA","NA","NA",null,{"v":0.485678,"d":"0.49"},{"v":0.110693,"d":"0.11"},{"v":4.38761258616173,"d":"4.39"},{"v":2.1334361454544,"d":"2.13"},1,1,"up","no"]
["ENSG00000249807","AC034229.1","ENST00000506299","NA","NA","NA","NA",null,0,{"v":0.053968,"d":"0.05"},"-inf","-inf",1,1,"down","no"]
["ENSG00000039987","BEST2","ENST00000549706","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0006811(ion transport);GO:0005886(plasma membrane);GO:0005254(chloride channel activity);GO:0006821(chloride transport);GO:0034707(chloride channel complex);GO:1902476(chloride transmembrane transport);GO:0003674(molecular_function);GO:0008150(biological_process);GO:0007608(sensory perception of smell);GO:0051899(membrane depolarization);GO:0005929(cilium)","04970(Salivary secretion)","NA","NA","bestrophin 2 [Source:HGNC Symbol;Acc:HGNC:17107]",0,0,1,0,1,1,"no","no"]
["MSTRG.13057","SLC22A7","ENST00000498232;ENST00000436107;ENST00000372585","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0055085(transmembrane transport);GO:0006810(transport);GO:0006811(ion transport);GO:0005886(plasma membrane);GO:0098656(anion transmembrane transport);GO:0015698(inorganic anion transport);GO:0015347(sodium-independent organic anion transmembrane transporter activity);GO:0043252(sodium-independent organic anion transport);GO:0016323(basolateral plasma membrane);GO:0005887(integral component of plasma membrane);GO:0005515(protein binding);GO:0015711(organic anion transport);GO:0015301(anion:anion antiporter activity);GO:0005452(inorganic anion exchanger activity);GO:0008514(organic anion transmembrane transporter activity);GO:0008514(organic anion transmembrane transporter activity)","04976(Bile secretion);04976(Bile secretion)","K08204","NA","solute carrier family 22 member 7 [Source:HGNC Symbol;Acc:HGNC:10971]",0,0,1,0,1,1,"no","no"]
["MSTRG.5561","AC093525.10","ENST00000625130","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000256162","SMLR1","ENST00000541421","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005515(protein binding)","NA","NA","NA","small leucine rich protein 1 [Source:HGNC Symbol;Acc:HGNC:44670]",0,0,1,0,1,1,"no","no"]
["ENSG00000205363","C15orf59","ENST00000379822;ENST00000569673","NA","NA","NA","NA","chromosome 15 open reading frame 59 [Source:HGNC Symbol;Acc:HGNC:33753]",0,0,1,0,1,1,"no","no"]
["ENSG00000250669","AC112206.4","ENST00000515142","NA","NA","NA","NA",null,{"v":0.124645,"d":"0.12"},0,"inf","inf",1,1,"up","no"]
["MSTRG.13861","LINC01004","ENST00000445184;ENST00000450686","NA","NA","NA","NA","long intergenic non-protein coding RNA 1004 [Source:HGNC Symbol;Acc:HGNC:48961]",{"v":0.338865694076039,"d":"0.34"},{"v":0.148561038019452,"d":"0.15"},{"v":2.28098631103849,"d":"2.28"},{"v":1.18965778858072,"d":"1.19"},1,1,"up","no"]
["MSTRG.4419","AL138995.1","ENST00000614633","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["MSTRG.7731","AC011444.4","ENST00000586415","NA","NA","NA","NA",null,{"v":0.087852,"d":"0.09"},0,"inf","inf",1,1,"up","no"]
["ENSG00000165370","GPR101","ENST00000298110","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0004930(G-protein coupled receptor activity);GO:0007186(G-protein coupled receptor signaling pathway);GO:0005886(plasma membrane);GO:0004871(signal transducer activity);GO:0007165(signal transduction);GO:0005887(integral component of plasma membrane);GO:0007267(cell-cell signaling);GO:0043235(receptor complex);GO:0071880(adenylate cyclase-activating adrenergic receptor signaling pathway);GO:0004935(adrenergic receptor activity)","NA","NA","NA","G protein-coupled receptor 101 [Source:HGNC Symbol;Acc:HGNC:14963]",0,0,1,0,1,1,"no","no"]
["ENSG00000233755","AL050344.1","ENST00000429666","NA","NA","NA","NA",null,0,{"v":0.176912396292005,"d":"0.18"},"-inf","-inf",1,1,"down","no"]
["ENSG00000107719","PALD1","ENST00000263563","GO:0005737(cytoplasm);GO:0035335(peptidyl-tyrosine dephosphorylation);GO:0005829(cytosol);GO:0005515(protein binding);GO:0006470(protein dephosphorylation);GO:0005634(nucleus);GO:0004725(protein tyrosine phosphatase activity);GO:0004722(protein serine/threonine phosphatase activity);GO:0008138(protein tyrosine/serine/threonine phosphatase activity)","NA","NA","NA","phosphatase domain containing, paladin 1 [Source:HGNC Symbol;Acc:HGNC:23530]",{"v":0.03487,"d":"0.03"},{"v":0.020866,"d":"0.02"},{"v":1.67113965302406,"d":"1.67"},{"v":0.740832300907517,"d":"0.74"},1,1,"up","no"]
["ENSG00000169436","COL22A1","ENST00000303045","GO:0005737(cytoplasm);GO:0005576(extracellular region);GO:0005581(collagen trimer);GO:0005578(proteinaceous extracellular matrix);GO:0005788(endoplasmic reticulum lumen)","04974(Protein digestion and absorption)","K16630","NA","collagen type XXII alpha 1 chain [Source:HGNC Symbol;Acc:HGNC:22989]",0,0,1,0,1,1,"no","no"]
["ENSG00000196604","POTEF","ENST00000409914","GO:0005737(cytoplasm);GO:0005615(extracellular space);GO:0070062(extracellular exosome);GO:0001895(retina homeostasis);GO:0005938(cell cortex);GO:0072562(blood microparticle)","NA","NA","NA","POTE ankyrin domain family member F [Source:HGNC Symbol;Acc:HGNC:33905]",0,0,1,0,1,1,"no","no"]
["MSTRG.3015","CCND2-AS2","ENST00000537370","NA","NA","NA","NA","CCND2 antisense RNA 2 [Source:HGNC Symbol;Acc:HGNC:49399]",{"v":0.107313,"d":"0.11"},{"v":0.129954,"d":"0.13"},{"v":0.825776813333949,"d":"0.83"},{"v":-0.27617618467765,"d":"-0.28"},1,1,"down","no"]
["ENSG00000164626","KCNK5","ENST00000359534","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005244(voltage-gated ion channel activity);GO:0005267(potassium channel activity);GO:0006811(ion transport);GO:0006813(potassium ion transport);GO:0034765(regulation of ion transmembrane transport);GO:0071805(potassium ion transmembrane transport);GO:0005249(voltage-gated potassium channel activity);GO:0071804(cellular potassium ion transport);GO:0005887(integral component of plasma membrane);GO:0030322(stabilization of membrane potential);GO:0007588(excretion);GO:0022841(potassium ion leak channel activity)","04974(Protein digestion and absorption);04742(Taste transduction)","K04916","NA","potassium two pore domain channel subfamily K member 5 [Source:HGNC Symbol;Acc:HGNC:6280]",{"v":0.176828,"d":"0.18"},{"v":0.214952,"d":"0.21"},{"v":0.822639472998623,"d":"0.82"},{"v":-0.281667796045573,"d":"-0.28"},1,1,"down","no"]
["ENSG00000128285","MCHR1","ENST00000249016","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0004930(G-protein coupled receptor activity);GO:0007186(G-protein coupled receptor signaling pathway);GO:0005886(plasma membrane);GO:0004871(signal transducer activity);GO:0007165(signal transduction);GO:0007218(neuropeptide signaling pathway);GO:0030273(melanin-concentrating hormone receptor activity);GO:0005887(integral component of plasma membrane);GO:0007631(feeding behavior);GO:0007268(chemical synaptic transmission);GO:0006091(generation of precursor metabolites and energy);GO:0007204(positive regulation of cytosolic calcium ion concentration);GO:0008188(neuropeptide receptor activity);GO:0007193(adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway);GO:0097730(non-motile cilium)","04080(Neuroactive ligand-receptor interaction)","K04320","NA","melanin concentrating hormone receptor 1 [Source:HGNC Symbol;Acc:HGNC:4479]",{"v":0.0335726673421141,"d":"0.03"},{"v":0.0343747217156366,"d":"0.03"},{"v":0.976667320243129,"d":"0.98"},{"v":-0.0340608706355383,"d":"-0.03"},1,1,"down","no"]
["ENSG00000164078","MST1R","ENST00000411578;ENST00000468525;ENST00000497001;ENST00000296474","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0004713(protein tyrosine kinase activity);GO:0007169(transmembrane receptor protein tyrosine kinase signaling pathway);GO:0018108(peptidyl-tyrosine phosphorylation);GO:0005515(protein binding);GO:0004714(transmembrane receptor protein tyrosine kinase activity);GO:0002376(immune system process);GO:0045087(innate immune response);GO:0005886(plasma membrane);GO:0009615(response to virus);GO:0005887(integral component of plasma membrane);GO:0007338(single fertilization);GO:0007165(signal transduction);GO:0019899(enzyme binding);GO:0009986(cell surface);GO:0006928(movement of cell or subcellular component);GO:0006952(defense response);GO:0051897(positive regulation of protein kinase B signaling);GO:0008284(positive regulation of cell proliferation);GO:0043406(positive regulation of MAP kinase activity);GO:0048012(hepatocyte growth factor receptor signaling pathway);GO:0005011(macrophage colony-stimulating factor receptor activity);GO:0038145(macrophage colony-stimulating factor signaling pathway);GO:0001725(stress fiber);GO:0005773(vacuole);GO:0005773(vacuole)","NA","NA","NA","macrophage stimulating 1 receptor [Source:HGNC Symbol;Acc:HGNC:7381]",{"v":0.0101141030083778,"d":"0.01"},{"v":0.0193802370525514,"d":"0.02"},{"v":0.521877156659768,"d":"0.52"},{"v":-0.938217840457051,"d":"-0.94"},1,1,"down","no"]
["ENSG00000284609","OR8B3","ENST00000354597","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0004930(G-protein coupled receptor activity);GO:0007186(G-protein coupled receptor signaling pathway);GO:0005886(plasma membrane);GO:0004871(signal transducer activity);GO:0007165(signal transduction);GO:0004984(olfactory receptor activity);GO:0007608(sensory perception of smell);GO:0050896(response to stimulus);GO:0050911(detection of chemical stimulus involved in sensory perception of smell);GO:0005549(odorant binding)","04740(Olfactory transduction)","K04257","NA","olfactory receptor family 8 subfamily B member 3 [Source:HGNC Symbol;Acc:HGNC:8472]",0,0,1,0,1,1,"no","no"]
["ENSG00000279278","AC245060.6","ENST00000624350","NA","NA","NA","NA",null,0,{"v":0.054337,"d":"0.05"},"-inf","-inf",1,1,"down","no"]
["MSTRG.8713","AC012358.1","ENST00000366153","NA","NA","NA","NA",null,0,{"v":0.005519,"d":"0.01"},"-inf","-inf",1,1,"down","no"]
["ENSG00000183840","GPR39","ENST00000329321","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0046872(metal ion binding);GO:0004930(G-protein coupled receptor activity);GO:0007186(G-protein coupled receptor signaling pathway);GO:0005886(plasma membrane);GO:0004871(signal transducer activity);GO:0007165(signal transduction);GO:0005887(integral component of plasma membrane)","NA","NA","NA","G protein-coupled receptor 39 [Source:HGNC Symbol;Acc:HGNC:4496]",{"v":0.0149877342781222,"d":"0.01"},0,"inf","inf",1,1,"up","no"]
["ENSG00000051341","POLQ","ENST00000621776;ENST00000474243","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0016740(transferase activity);GO:0003677(DNA binding);GO:0005694(chromosome);GO:0006281(DNA repair);GO:0006974(cellular response to DNA damage stimulus);GO:0006260(DNA replication);GO:0016779(nucleotidyltransferase activity);GO:0003887(DNA-directed DNA polymerase activity);GO:0071897(DNA biosynthetic process);GO:0005737(cytoplasm);GO:0006261(DNA-dependent DNA replication);GO:0005515(protein binding);GO:0005654(nucleoplasm);GO:0003682(chromatin binding);GO:0006284(base-excision repair);GO:0003684(damaged DNA binding);GO:0051260(protein homooligomerization);GO:0000724(double-strand break repair via homologous recombination);GO:0006302(double-strand break repair);GO:0043142(single-stranded DNA-dependent ATPase activity);GO:0051575(5'-deoxyribose-5-phosphate lyase activity);GO:0016446(somatic hypermutation of immunoglobulin genes);GO:0097681(double-strand break repair via alternative nonhomologous end joining);GO:2000042(negative regulation of double-strand break repair via homologous recombination);GO:2000042(negative regulation of double-strand break repair via homologous recombination)","NA","NA","NA","DNA polymerase theta [Source:HGNC Symbol;Acc:HGNC:9186]",{"v":0.0447596356382979,"d":"0.04"},{"v":0.0162421654255319,"d":"0.02"},{"v":2.75576774805765,"d":"2.76"},{"v":1.46245430500715,"d":"1.46"},1,1,"up","no"]
["MSTRG.7733","ACSBG2","ENST00000586696;ENST00000588304","GO:0003824(catalytic activity);GO:0008152(metabolic process);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0005829(cytosol);GO:0006629(lipid metabolic process);GO:0006631(fatty acid metabolic process);GO:0016874(ligase activity);GO:0007275(multicellular organism development);GO:0030154(cell differentiation);GO:0001676(long-chain fatty acid metabolic process);GO:0007283(spermatogenesis);GO:0035338(long-chain fatty-acyl-CoA biosynthetic process);GO:0005739(mitochondrion);GO:0004467(long-chain fatty acid-CoA ligase activity);GO:0102391(decanoate--CoA ligase activity);GO:0031957(very long-chain fatty acid-CoA ligase activity);GO:0047617(acyl-CoA hydrolase activity);GO:0016021(integral component of membrane);GO:0016021(integral component of membrane)","00061(Fatty acid biosynthesis);00071(Fatty acid degradation);04920(Adipocytokine signaling pathway);03320(PPAR signaling pathway);03320(PPAR signaling pathway)","K15013","EC:6.2.1.3","acyl-CoA synthetase bubblegum family member 2 [Source:HGNC Symbol;Acc:HGNC:24174]",{"v":0.0308212396286626,"d":"0.03"},{"v":0.0342149617058312,"d":"0.03"},{"v":0.900811752871545,"d":"0.90"},{"v":-0.150702444535291,"d":"-0.15"},1,1,"down","no"]
["ENSG00000175718","RBMXL3","ENST00000424776","GO:0003676(nucleic acid binding);GO:0003723(RNA binding)","03040(Spliceosome)","K12885","NA","RNA binding motif protein, X-linked like 3 [Source:HGNC Symbol;Acc:HGNC:26859]",0,0,1,0,1,1,"no","no"]
["MSTRG.11939","CENPU","ENST00000510146;ENST00000281453;ENST00000514781","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0005694(chromosome);GO:0005515(protein binding);GO:0005815(microtubule organizing center);GO:0000775(chromosome, centromeric region);GO:0000776(kinetochore);GO:0000777(condensed chromosome kinetochore);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0016032(viral process);GO:0034080(CENP-A containing nucleosome assembly);GO:0007062(sister chromatid cohesion);GO:0043009(chordate embryonic development);GO:0043009(chordate embryonic development)","NA","NA","NA","centromere protein U [Source:HGNC Symbol;Acc:HGNC:21348]",{"v":0.292162675245513,"d":"0.29"},{"v":0.22627564036573,"d":"0.23"},{"v":1.29118041506054,"d":"1.29"},{"v":0.368690600744035,"d":"0.37"},1,1,"up","no"]
["ENSG00000106278","PTPRZ1","ENST00000393386;ENST00000483995","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016787(hydrolase activity);GO:0004725(protein tyrosine phosphatase activity);GO:0016791(phosphatase activity);GO:0006470(protein dephosphorylation);GO:0016311(dephosphorylation);GO:0005886(plasma membrane);GO:0004721(phosphoprotein phosphatase activity);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0035335(peptidyl-tyrosine dephosphorylation);GO:0005887(integral component of plasma membrane);GO:0031226(intrinsic component of plasma membrane);GO:0007417(central nervous system development);GO:0007611(learning or memory);GO:0005001(transmembrane receptor protein tyrosine phosphatase activity);GO:0002244(hematopoietic progenitor cell differentiation);GO:0007409(axonogenesis);GO:0048709(oligodendrocyte differentiation);GO:0070445(regulation of oligodendrocyte progenitor proliferation);GO:0005578(proteinaceous extracellular matrix);GO:0072534(perineuronal net);GO:0072534(perineuronal net)","05120(Epithelial cell signaling in Helicobacter pylori infection);05120(Epithelial cell signaling in Helicobacter pylori infection)","K08114","EC:3.1.3.48","protein tyrosine phosphatase, receptor type Z1 [Source:HGNC Symbol;Acc:HGNC:9685]",0,0,1,0,1,1,"no","no"]
["ENSG00000243438","LARP1BP2","ENST00000486594","NA","NA","NA","NA","La ribonucleoprotein domain family member 1B pseudogene 2 [Source:HGNC Symbol;Acc:HGNC:44084]",0,{"v":0.098057,"d":"0.10"},"-inf","-inf",1,1,"down","no"]
["MSTRG.2930","AP003396.1","ENST00000501918","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000137857","DUOX1","ENST00000321429;ENST00000561166;ENST00000558446;ENST00000558991","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0046872(metal ion binding);GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0005509(calcium ion binding);GO:0005886(plasma membrane);GO:0020037(heme binding);GO:0098869(cellular oxidant detoxification);GO:0004601(peroxidase activity);GO:0006979(response to oxidative stress);GO:0042446(hormone biosynthetic process);GO:0042744(hydrogen peroxide catabolic process);GO:0016324(apical plasma membrane);GO:0006590(thyroid hormone generation);GO:0019221(cytokine-mediated signaling pathway);GO:0016174(NAD(P)H oxidase activity);GO:0051591(response to cAMP);GO:0050661(NADP binding);GO:0050665(hydrogen peroxide biosynthetic process);GO:0042554(superoxide anion generation);GO:0042335(cuticle development);GO:0072593(reactive oxygen species metabolic process);GO:0072593(reactive oxygen species metabolic process)","NA","NA","NA","dual oxidase 1 [Source:HGNC Symbol;Acc:HGNC:3062]",{"v":0.0821931434426229,"d":"0.08"},{"v":0.0319112592213115,"d":"0.03"},{"v":2.57567847362574,"d":"2.58"},{"v":1.3649525105888,"d":"1.36"},1,1,"up","no"]
["MSTRG.5907","AC026470.3","ENST00000563994","NA","NA","NA","NA",null,{"v":0.102013,"d":"0.10"},{"v":0.090048,"d":"0.09"},{"v":1.13287357853589,"d":"1.13"},{"v":0.179986874578023,"d":"0.18"},1,1,"up","no"]
["MSTRG.5086","AC090971.1","ENST00000559302","NA","NA","NA","NA",null,0,{"v":0.000496,"d":"0.00"},"-inf","-inf",1,1,"down","no"]
["MSTRG.6141","AC009163.7","ENST00000621929","NA","NA","NA","NA",null,{"v":0.247847,"d":"0.25"},{"v":0.139123,"d":"0.14"},{"v":1.78149551116638,"d":"1.78"},{"v":0.833088848317598,"d":"0.83"},1,1,"up","no"]
["MSTRG.3772","AC026367.3","ENST00000619032","NA","NA","NA","NA",null,0,{"v":0.086257,"d":"0.09"},"-inf","-inf",1,1,"down","no"]
["ENSG00000105376","ICAM5","ENST00000587398;ENST00000221980","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0007155(cell adhesion);GO:0005515(protein binding);GO:0016337(single organismal cell-cell adhesion);GO:0050776(regulation of immune response);GO:0005886(plasma membrane);GO:0005887(integral component of plasma membrane);GO:0030198(extracellular matrix organization);GO:0005178(integrin binding);GO:0006909(phagocytosis);GO:0006909(phagocytosis)","NA","NA","NA","intercellular adhesion molecule 5 [Source:HGNC Symbol;Acc:HGNC:5348]",{"v":0.135049923195084,"d":"0.14"},{"v":0.0130291858678955,"d":"0.01"},{"v":10.3651850978543,"d":"10.37"},{"v":3.37367397470875,"d":"3.37"},1,1,"up","no"]
["ENSG00000276517","AL133243.3","ENST00000617415","NA","NA","NA","NA",null,{"v":0.035366,"d":"0.04"},{"v":0.101143,"d":"0.10"},{"v":0.349663347933124,"d":"0.35"},{"v":-1.51596151568437,"d":"-1.52"},1,1,"down","no"]
["ENSG00000240216","CPHL1P","ENST00000482639;ENST00000461341","NA","NA","NA","NA","ceruloplasmin and hephaestin-like 1 pseudogene [Source:HGNC Symbol;Acc:HGNC:31714]",{"v":0.0201813220640569,"d":"0.02"},{"v":0.0129360343162176,"d":"0.01"},{"v":1.56008569324496,"d":"1.56"},{"v":0.641625276410658,"d":"0.64"},1,1,"up","no"]
["MSTRG.9696","MMP24","MSTRG.9696.1","NA","NA","NA","NA",null,{"v":2.310491,"d":"2.31"},{"v":0.13344,"d":"0.13"},{"v":17.3148306354916,"d":"17.31"},{"v":4.11393637081226,"d":"4.11"},1,1,"up","no"]
["ENSG00000214819","CDRT15L2","ENST00000399044","GO:0016020(membrane);GO:0016021(integral component of membrane)","NA","NA","NA","CMT1A duplicated region transcript 15 like 2 [Source:HGNC Symbol;Acc:HGNC:34075]",0,0,1,0,1,1,"no","no"]
["ENSG00000272384","AC016405.3","ENST00000607710","NA","NA","NA","NA",null,{"v":0.061767,"d":"0.06"},0,"inf","inf",1,1,"up","no"]
["ENSG00000086548","CEACAM6","ENST00000199764;ENST00000595740","GO:0008284(positive regulation of cell proliferation);GO:0030335(positive regulation of cell migration);GO:0016020(membrane);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0005615(extracellular space);GO:0031225(anchored component of membrane);GO:0050900(leukocyte migration);GO:0005887(integral component of plasma membrane);GO:0043312(neutrophil degranulation);GO:0007165(signal transduction);GO:0007267(cell-cell signaling);GO:0035577(azurophil granule membrane);GO:0035577(azurophil granule membrane)","NA","NA","NA","carcinoembryonic antigen related cell adhesion molecule 6 [Source:HGNC Symbol;Acc:HGNC:1818]",{"v":0.083714873197903,"d":"0.08"},{"v":0.0931393840104849,"d":"0.09"},{"v":0.898812828614789,"d":"0.90"},{"v":-0.153907378862135,"d":"-0.15"},1,1,"down","no"]
["ENSG00000264539","MIR548AR","ENST00000582191","NA","NA","NA","NA","microRNA 548ar [Source:HGNC Symbol;Acc:HGNC:43455]",{"v":0.238068,"d":"0.24"},{"v":0.539422,"d":"0.54"},{"v":0.441339062922906,"d":"0.44"},{"v":-1.18004064897601,"d":"-1.18"},1,1,"down","no"]
["ENSG00000230936","AC073347.1","ENST00000421633","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000280212","AC012254.5","ENST00000623573","NA","NA","NA","NA",null,{"v":0.222259,"d":"0.22"},0,"inf","inf",1,1,"up","no"]
["MSTRG.15324","UBQLN2","ENST00000338222","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0006914(autophagy);GO:0031410(cytoplasmic vesicle);GO:0005776(autophagosome);GO:0030433(ubiquitin-dependent ERAD pathway);GO:0016241(regulation of macroautophagy);GO:2000785(regulation of autophagosome assembly);GO:1900186(negative regulation of clathrin-dependent endocytosis);GO:1903071(positive regulation of ER-associated ubiquitin-dependent protein catabolic process);GO:1904021(negative regulation of G-protein coupled receptor internalization)","04141(Protein processing in endoplasmic reticulum)","K04523","NA","ubiquilin 2 [Source:HGNC Symbol;Acc:HGNC:12509]",0,0,1,0,1,1,"no","no"]
["MSTRG.3960","RLIMP1","ENST00000339626","NA","NA","NA","NA","ring finger protein, LIM domain interacting pseudogene 1 [Source:HGNC Symbol;Acc:HGNC:39682]",{"v":0.027621,"d":"0.03"},0,"inf","inf",1,1,"up","no"]
["MSTRG.10578","AL121672.2","ENST00000412643","NA","NA","NA","NA",null,{"v":0.061269,"d":"0.06"},{"v":0.302971,"d":"0.30"},{"v":0.202227275877889,"d":"0.20"},{"v":-2.30595049764701,"d":"-2.31"},1,1,"down","no"]
["ENSG00000109063","MYH3","ENST00000579928;ENST00000577963;ENST00000583535;ENST00000579489","GO:0005737(cytoplasm);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0003774(motor activity);GO:0016459(myosin complex);GO:0003779(actin binding);GO:0006470(protein dephosphorylation);GO:0005516(calmodulin binding);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0032982(myosin filament);GO:0030016(myofibril);GO:0007517(muscle organ development);GO:0003009(skeletal muscle contraction);GO:0030049(muscle filament sliding);GO:0045214(sarcomere organization);GO:0000146(microfilament motor activity);GO:0030048(actin filament-based movement);GO:0046034(ATP metabolic process);GO:0005859(muscle myosin complex);GO:0030017(sarcomere);GO:0060325(face morphogenesis);GO:0017018(myosin phosphatase activity);GO:0042623(ATPase activity, coupled);GO:0051015(actin filament binding);GO:0030326(embryonic limb morphogenesis);GO:0043292(contractile fiber);GO:0043292(contractile fiber)","04530(Tight junction);04530(Tight junction)","K10352","NA","myosin heavy chain 3 [Source:HGNC Symbol;Acc:HGNC:7573]",{"v":0.266601399012567,"d":"0.27"},{"v":0.0517843430580491,"d":"0.05"},{"v":5.14830126769616,"d":"5.15"},{"v":2.36409647948984,"d":"2.36"},1,1,"up","no"]
["ENSG00000275695","UBE2Q2P6","ENST00000617217;ENST00000612666","NA","NA","NA","NA","ubiquitin conjugating enzyme E2 Q2 pseudogene 6 [Source:HGNC Symbol;Acc:HGNC:49412]",0,0,1,0,1,1,"no","no"]
["ENSG00000204501","PRAMEF15","ENST00000376152","GO:0043066(negative regulation of apoptotic process);GO:0008284(positive regulation of cell proliferation);GO:0045596(negative regulation of cell differentiation);GO:0045892(negative regulation of transcription, DNA-templated)","NA","NA","NA","PRAME family member 15 [Source:HGNC Symbol;Acc:HGNC:26764]",0,0,1,0,1,1,"no","no"]
["ENSG00000239392","AL354989.2","ENST00000435838","NA","NA","NA","NA",null,0,{"v":0.04957,"d":"0.05"},"-inf","-inf",1,1,"down","no"]
["ENSG00000272183","AC005041.3","ENST00000606287","NA","NA","NA","NA",null,{"v":0.081849,"d":"0.08"},0,"inf","inf",1,1,"up","no"]
["ENSG00000154065","ANKRD29","ENST00000585908;ENST00000591280;ENST00000592179","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016021(integral component of membrane)","NA","NA","NA","ankyrin repeat domain 29 [Source:HGNC Symbol;Acc:HGNC:27110]",{"v":0.00831178297606008,"d":"0.01"},{"v":0.00796306931622594,"d":"0.01"},{"v":1.04379136310211,"d":"1.04"},{"v":0.0618333694764125,"d":"0.06"},1,1,"up","no"]
["ENSG00000226800","CACTIN-AS1","ENST00000592274","NA","NA","NA","NA","CACTIN antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:31391]",{"v":0.107356,"d":"0.11"},{"v":0.118805,"d":"0.12"},{"v":0.903632002020117,"d":"0.90"},{"v":-0.146192730377952,"d":"-0.15"},1,1,"down","no"]
["ENSG00000213881","NPM1P6","ENST00000521088","NA","NA","NA","NA","nucleophosmin 1 pseudogene 6 [Source:HGNC Symbol;Acc:HGNC:7926]",{"v":0.12157,"d":"0.12"},0,"inf","inf",1,1,"up","no"]
["ENSG00000152402","GUCY1A2","ENST00000526355","GO:0005737(cytoplasm);GO:0000166(nucleotide binding);GO:0035556(intracellular signal transduction);GO:0016829(lyase activity);GO:0005525(GTP binding);GO:0005515(protein binding);GO:0020037(heme binding);GO:0016849(phosphorus-oxygen lyase activity);GO:0009190(cyclic nucleotide biosynthetic process);GO:0005886(plasma membrane);GO:0004383(guanylate cyclase activity);GO:0006182(cGMP biosynthetic process);GO:0007165(signal transduction);GO:0008074(guanylate cyclase complex, soluble);GO:0030828(positive regulation of cGMP biosynthetic process)","00230(Purine metabolism);04022(cGMP - PKG signaling pathway);04540(Gap junction);04611(Platelet activation);04921(Oxytocin signaling pathway);04924(Renin secretion);04270(Vascular smooth muscle contraction);04970(Salivary secretion);04730(Long-term depression);04713(Circadian entrainment)","K12318","EC:4.6.1.2","guanylate cyclase 1 soluble subunit alpha 2 [Source:HGNC Symbol;Acc:HGNC:4684]",0,0,1,0,1,1,"no","no"]
["ENSG00000155052","CNTNAP5","ENST00000431078","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0007155(cell adhesion)","NA","NA","NA","contactin associated protein like 5 [Source:HGNC Symbol;Acc:HGNC:18748]",0,0,1,0,1,1,"no","no"]
["MSTRG.10461","PRDX3P1","ENST00000418695","NA","NA","NA","NA","peroxiredoxin 3 pseudogene 1 [Source:HGNC Symbol;Acc:HGNC:39264]",0,{"v":0.267019,"d":"0.27"},"-inf","-inf",1,1,"down","no"]
["ENSG00000167791","CABP2","ENST00000545205","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0046872(metal ion binding);GO:0005509(calcium ion binding);GO:0005794(Golgi apparatus);GO:0005886(plasma membrane);GO:0048471(perinuclear region of cytoplasm);GO:0007165(signal transduction)","NA","NA","NA","calcium binding protein 2 [Source:HGNC Symbol;Acc:HGNC:1385]",0,0,1,0,1,1,"no","no"]
["ENSG00000256612","CYP2B7P","ENST00000593298;ENST00000599198","NA","NA","NA","NA","cytochrome P450 family 2 subfamily B member 7, pseudogene [Source:HGNC Symbol;Acc:HGNC:2616]",0,{"v":0.0250451326279528,"d":"0.03"},"-inf","-inf",1,1,"down","no"]
["ENSG00000164853","UNCX","ENST00000316333","GO:0005634(nucleus);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0043565(sequence-specific DNA binding);GO:0007275(multicellular organism development);GO:0007399(nervous system development);GO:0030154(cell differentiation);GO:0001502(cartilage condensation);GO:0007389(pattern specification process);GO:0010468(regulation of gene expression);GO:0021516(dorsal spinal cord development);GO:0021889(olfactory bulb interneuron differentiation);GO:0035726(common myeloid progenitor cell proliferation);GO:0045595(regulation of cell differentiation)","NA","NA","NA","UNC homeobox [Source:HGNC Symbol;Acc:HGNC:33194]",0,0,1,0,1,1,"no","no"]
["ENSG00000065325","GLP2R","ENST00000262441","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0004930(G-protein coupled receptor activity);GO:0007186(G-protein coupled receptor signaling pathway);GO:0004888(transmembrane signaling receptor activity);GO:0007166(cell surface receptor signaling pathway);GO:0005886(plasma membrane);GO:0004871(signal transducer activity);GO:0007165(signal transduction);GO:0071377(cellular response to glucagon stimulus);GO:0007188(adenylate cyclase-modulating G-protein coupled receptor signaling pathway);GO:0008284(positive regulation of cell proliferation);GO:0004967(glucagon receptor activity)","04080(Neuroactive ligand-receptor interaction)","K04582","NA","glucagon like peptide 2 receptor [Source:HGNC Symbol;Acc:HGNC:4325]",0,0,1,0,1,1,"no","no"]
["ENSG00000270168","AC004233.2","ENST00000573315","NA","NA","NA","NA",null,{"v":0.010502,"d":"0.01"},{"v":0.000981,"d":"0.00"},{"v":10.7054026503568,"d":"10.71"},{"v":3.420267154109,"d":"3.42"},1,1,"up","no"]
["ENSG00000235433","MTATP6P17","ENST00000431030","NA","NA","NA","NA","mitochondrially encoded ATP synthase 6 pseudogene 17 [Source:HGNC Symbol;Acc:HGNC:52062]",0,0,1,0,1,1,"no","no"]
["ENSG00000232852","CICP4","ENST00000447359","NA","NA","NA","NA","capicua transcriptional repressor pseudogene 4 [Source:HGNC Symbol;Acc:HGNC:37753]",0,{"v":0.061059,"d":"0.06"},"-inf","-inf",1,1,"down","no"]
["ENSG00000185437","SH3BGR","ENST00000380634;ENST00000333634;ENST00000380637;ENST00000423596;ENST00000380631;ENST00000458295","GO:0009967(positive regulation of signal transduction);GO:0005829(cytosol);GO:0017124(SH3 domain binding);GO:0006461(protein complex assembly);GO:0005070(SH3/SH2 adaptor activity);GO:0005070(SH3/SH2 adaptor activity)","NA","NA","NA","SH3 domain binding glutamate rich protein [Source:HGNC Symbol;Acc:HGNC:10822]",{"v":0.177579547826087,"d":"0.18"},{"v":0.342904232107023,"d":"0.34"},{"v":0.517869221779284,"d":"0.52"},{"v":-0.949340276727298,"d":"-0.95"},1,1,"down","no"]
["ENSG00000141391","PRELID3A","ENST00000589565;ENST00000336990;ENST00000592149;ENST00000587735","GO:0006810(transport);GO:0005739(mitochondrion);GO:0006869(lipid transport);GO:0005515(protein binding);GO:1903955(positive regulation of protein targeting to mitochondrion);GO:0005758(mitochondrial intermembrane space);GO:0015914(phospholipid transport);GO:1990050(phosphatidic acid transporter activity);GO:1990050(phosphatidic acid transporter activity)","NA","NA","NA","PRELI domain containing 3A [Source:HGNC Symbol;Acc:HGNC:24639]",{"v":0.040163118426031,"d":"0.04"},0,"inf","inf",1,1,"up","no"]
["ENSG00000215269","GAGE12G","ENST00000445148","GO:0005515(protein binding);GO:0003674(molecular_function);GO:0008150(biological_process);GO:0005575(cellular_component)","NA","NA","NA","G antigen 12G [Source:HGNC Symbol;Acc:HGNC:31907]",0,0,1,0,1,1,"no","no"]
["ENSG00000100249","C22orf31","ENST00000216071","NA","NA","NA","NA","chromosome 22 open reading frame 31 [Source:HGNC Symbol;Acc:HGNC:26931]",0,0,1,0,1,1,"no","no"]
["ENSG00000187566","NHLRC1","ENST00000340650","GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0016740(transferase activity);GO:0016567(protein ubiquitination);GO:0005783(endoplasmic reticulum);GO:0005515(protein binding);GO:0006914(autophagy);GO:0005829(cytosol);GO:0004842(ubiquitin-protein transferase activity);GO:0043161(proteasome-mediated ubiquitin-dependent protein catabolic process);GO:0005978(glycogen biosynthetic process);GO:0000209(protein polyubiquitination);GO:0061630(ubiquitin protein ligase activity);GO:0031398(positive regulation of protein ubiquitination);GO:0048471(perinuclear region of cytoplasm)","04120(Ubiquitin mediated proteolysis)","K10602","EC:2.3.2.27","NHL repeat containing E3 ubiquitin protein ligase 1 [Source:HGNC Symbol;Acc:HGNC:21576]",{"v":0.35296,"d":"0.35"},{"v":0.226087,"d":"0.23"},{"v":1.56116893054444,"d":"1.56"},{"v":0.642626656516526,"d":"0.64"},1,1,"up","no"]
["ENSG00000254965","C1DP5","ENST00000525775","NA","NA","NA","NA","C1D nuclear receptor corepressor pseudogene 5 [Source:HGNC Symbol;Acc:HGNC:51613]",0,{"v":0.132877,"d":"0.13"},"-inf","-inf",1,1,"down","no"]
["ENSG00000242808","SOX2-OT","ENST00000630482","NA","NA","NA","NA","SOX2 overlapping transcript [Source:HGNC Symbol;Acc:HGNC:20209]",0,{"v":0.00410152332828028,"d":"0.00"},"-inf","-inf",1,1,"down","no"]
["ENSG00000213036","AL445305.1","ENST00000432577","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000262482","AC004034.1","ENST00000573260","NA","NA","NA","NA",null,{"v":0.125225,"d":"0.13"},{"v":0.322299,"d":"0.32"},{"v":0.388536731420203,"d":"0.39"},{"v":-1.36387710054574,"d":"-1.36"},1,1,"down","no"]
["ENSG00000133063","CHIT1","ENST00000503786;ENST00000367229;ENST00000506427;ENST00000460619;ENST00000513472;ENST00000479483;ENST00000484834","GO:0016787(hydrolase activity);GO:0005576(extracellular region);GO:0005975(carbohydrate metabolic process);GO:0008152(metabolic process);GO:0004553(hydrolase activity, hydrolyzing O-glycosyl compounds);GO:0016798(hydrolase activity, acting on glycosyl bonds);GO:0006955(immune response);GO:0005615(extracellular space);GO:0008061(chitin binding);GO:0005764(lysosome);GO:0043312(neutrophil degranulation);GO:0035580(specific granule lumen);GO:1904724(tertiary granule lumen);GO:0044245(polysaccharide digestion);GO:0004568(chitinase activity);GO:0008843(endochitinase activity);GO:0000272(polysaccharide catabolic process);GO:0006030(chitin metabolic process);GO:0006032(chitin catabolic process);GO:0009617(response to bacterium);GO:0009617(response to bacterium)","00520(Amino sugar and nucleotide sugar metabolism);00520(Amino sugar and nucleotide sugar metabolism)","K01183","EC:3.2.1.14","chitinase 1 [Source:HGNC Symbol;Acc:HGNC:1936]",{"v":0.0372541455368693,"d":"0.04"},{"v":0.0201431562742561,"d":"0.02"},{"v":1.84946912140486,"d":"1.85"},{"v":0.887111213536816,"d":"0.89"},1,1,"up","no"]
["ENSG00000213080","AL354714.2","ENST00000425270","NA","NA","NA","NA",null,{"v":0.04722,"d":"0.05"},{"v":0.023196,"d":"0.02"},{"v":2.03569580962235,"d":"2.04"},{"v":1.02552199818361,"d":"1.03"},1,1,"up","no"]
["ENSG00000131914","LIN28A","ENST00000326279","GO:0051897(positive regulation of protein kinase B signaling);GO:0071333(cellular response to glucose stimulus);GO:0032008(positive regulation of TOR signaling);GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0005783(endoplasmic reticulum);GO:0005730(nucleolus);GO:0031047(gene silencing by RNA);GO:0000932(P-body);GO:0005515(protein binding);GO:0005829(cytosol);GO:0017148(negative regulation of translation);GO:0010494(cytoplasmic stress granule);GO:0035019(somatic stem cell population maintenance);GO:0019827(stem cell population maintenance);GO:0005791(rough endoplasmic reticulum);GO:1903800(positive regulation of production of miRNAs involved in gene silencing by miRNA);GO:0035198(miRNA binding);GO:0002151(G-quadruplex RNA binding);GO:1990825(sequence-specific mRNA binding);GO:0031054(pre-miRNA processing);GO:0010587(miRNA catabolic process);GO:0031123(RNA 3'-end processing);GO:0003729(mRNA binding);GO:0031369(translation initiation factor binding);GO:0007281(germ cell development);GO:0010586(miRNA metabolic process);GO:0045666(positive regulation of neuron differentiation);GO:0045686(negative regulation of glial cell differentiation);GO:0045727(positive regulation of translation);GO:0048863(stem cell differentiation);GO:0060964(regulation of gene silencing by miRNA);GO:1901724(positive regulation of cell proliferation involved in kidney development)","NA","NA","NA","lin-28 homolog A [Source:HGNC Symbol;Acc:HGNC:15986]",0,0,1,0,1,1,"no","no"]
["MSTRG.152","AL109811.1","ENST00000452378","NA","NA","NA","NA",null,{"v":0.012091,"d":"0.01"},{"v":0.013944,"d":"0.01"},{"v":0.867111302352266,"d":"0.87"},{"v":-0.20571090530935,"d":"-0.21"},1,1,"down","no"]
["ENSG00000167825","OR5I1","ENST00000301532","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0004930(G-protein coupled receptor activity);GO:0007186(G-protein coupled receptor signaling pathway);GO:0005886(plasma membrane);GO:0004871(signal transducer activity);GO:0007165(signal transduction);GO:0004984(olfactory receptor activity);GO:0007608(sensory perception of smell);GO:0050896(response to stimulus);GO:0050911(detection of chemical stimulus involved in sensory perception of smell);GO:0005549(odorant binding)","04740(Olfactory transduction)","K04257","NA","olfactory receptor family 5 subfamily I member 1 [Source:HGNC Symbol;Acc:HGNC:8347]",0,0,1,0,1,1,"no","no"]
["MSTRG.4839","IGHV3-47","ENST00000425060","NA","NA","NA","NA","immunoglobulin heavy variable 3-47 (pseudogene) [Source:HGNC Symbol;Acc:HGNC:5605]",{"v":0.157516,"d":"0.16"},0,"inf","inf",1,1,"up","no"]
["ENSG00000240710","AL512306.3","ENST00000453895","NA","NA","NA","NA",null,{"v":0.491822,"d":"0.49"},{"v":0.04359,"d":"0.04"},{"v":11.2829089240652,"d":"11.28"},{"v":3.49606716167441,"d":"3.50"},1,1,"up","no"]
["ENSG00000227001","NBPF2P","ENST00000453025","NA","NA","NA","NA","NBPF member 2, pseudogene [Source:HGNC Symbol;Acc:HGNC:31987]",{"v":0.77488,"d":"0.77"},{"v":0.59861,"d":"0.60"},{"v":1.29446551176893,"d":"1.29"},{"v":0.372356528264099,"d":"0.37"},1,1,"up","no"]
["ENSG00000166359","WDR88","ENST00000592765;ENST00000361680","NA","NA","NA","NA","WD repeat domain 88 [Source:HGNC Symbol;Acc:HGNC:26999]",{"v":0.189045389462249,"d":"0.19"},{"v":0.098200907115698,"d":"0.10"},{"v":1.92508801613737,"d":"1.93"},{"v":0.944924408167043,"d":"0.94"},1,1,"up","no"]
["ENSG00000261799","AC007406.5","ENST00000570140","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000182397","DNM1P46","ENST00000341853","NA","NA","NA","NA","dynamin 1 pseudogene 46 [Source:HGNC Symbol;Acc:HGNC:35199]",{"v":0.012422106559437,"d":"0.01"},{"v":0.0159681163608947,"d":"0.02"},{"v":0.777931866144103,"d":"0.78"},{"v":-0.362284290164911,"d":"-0.36"},1,1,"down","no"]
["ENSG00000227407","AC245884.1","ENST00000457113","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000265018","AGAP12P","ENST00000603888;ENST00000585227","NA","NA","NA","NA","ArfGAP with GTPase domain, ankyrin repeat and PH domain 12, pseudogene [Source:HGNC Symbol;Acc:HGNC:23661]",{"v":0.162700382083333,"d":"0.16"},{"v":0.114492099166667,"d":"0.11"},{"v":1.42106209308372,"d":"1.42"},{"v":0.506969594289919,"d":"0.51"},1,1,"up","no"]
["ENSG00000091664","SLC17A6","ENST00000534115","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0055085(transmembrane transport);GO:0015293(symporter activity);GO:0006811(ion transport);GO:0006814(sodium ion transport);GO:0030054(cell junction);GO:0045202(synapse);GO:0031410(cytoplasmic vesicle);GO:0043005(neuron projection);GO:0030672(synaptic vesicle membrane);GO:0006836(neurotransmitter transport);GO:0005313(L-glutamate transmembrane transporter activity);GO:0089711(L-glutamate transmembrane transport);GO:0098700(neurotransmitter loading into synaptic vesicle)","04724(Glutamatergic synapse);04723(Retrograde endocannabinoid signaling);04721(Synaptic vesicle cycle);05033(Nicotine addiction)","NA","NA","solute carrier family 17 member 6 [Source:HGNC Symbol;Acc:HGNC:16703]",0,0,1,0,1,1,"no","no"]
["ENSG00000133687","TMTC1","ENST00000546582;ENST00000553189;ENST00000551659;ENST00000256062","GO:0006396(RNA processing);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005739(mitochondrion);GO:0005739(mitochondrion)","NA","NA","NA","transmembrane and tetratricopeptide repeat containing 1 [Source:HGNC Symbol;Acc:HGNC:24099]",{"v":0.0834760443427166,"d":"0.08"},{"v":0.0206095716042635,"d":"0.02"},{"v":4.05035320217175,"d":"4.05"},{"v":2.01804772054129,"d":"2.02"},1,1,"up","no"]
["ENSG00000220494","YAP1P1","ENST00000401504","NA","NA","NA","NA","Yes associated protein 1 pseudogene 1 [Source:HGNC Symbol;Acc:HGNC:38016]",{"v":0.038133,"d":"0.04"},0,"inf","inf",1,1,"up","no"]
["ENSG00000284723","OR8S1","ENST00000641651","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0004930(G-protein coupled receptor activity);GO:0007186(G-protein coupled receptor signaling pathway);GO:0005886(plasma membrane);GO:0004871(signal transducer activity);GO:0007165(signal transduction);GO:0004984(olfactory receptor activity);GO:0007608(sensory perception of smell);GO:0050896(response to stimulus);GO:0050911(detection of chemical stimulus involved in sensory perception of smell);GO:0004888(transmembrane signaling receptor activity);GO:0050907(detection of chemical stimulus involved in sensory perception)","04740(Olfactory transduction)","NA","NA","olfactory receptor family 8 subfamily S member 1 [Source:HGNC Symbol;Acc:HGNC:19628]",0,0,1,0,1,1,"no","no"]
["MSTRG.3122","AC092821.2","ENST00000545710","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["MSTRG.5078","AC066613.1","ENST00000559977","NA","NA","NA","NA",null,{"v":0.647201479809976,"d":"0.65"},{"v":0.329934997624703,"d":"0.33"},{"v":1.96160299595183,"d":"1.96"},{"v":0.972033087567893,"d":"0.97"},1,1,"up","no"]
["ENSG00000143125","PROK1","ENST00000271331","GO:0008083(growth factor activity);GO:0000187(activation of MAPK activity);GO:0008284(positive regulation of cell proliferation);GO:0045765(regulation of angiogenesis);GO:0005576(extracellular region);GO:0001664(G-protein coupled receptor binding);GO:0001525(angiogenesis);GO:0051781(positive regulation of cell division);GO:0007623(circadian rhythm)","NA","NA","NA","prokineticin 1 [Source:HGNC Symbol;Acc:HGNC:18454]",0,0,1,0,1,1,"no","no"]
["ENSG00000224094","RPS24P8","ENST00000431490","NA","NA","NA","NA","ribosomal protein S24 pseudogene 8 [Source:HGNC Symbol;Acc:HGNC:37016]",{"v":1.399271,"d":"1.40"},{"v":1.049242,"d":"1.05"},{"v":1.3336017810953,"d":"1.33"},{"v":0.415327936233344,"d":"0.42"},1,1,"up","no"]
["ENSG00000280561","AL158835.3","ENST00000625908","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000187979","AC008079.1","ENST00000434390","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000253831","ETV3L","ENST00000454449","GO:0005634(nucleus);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0043565(sequence-specific DNA binding);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0000981(RNA polymerase II transcription factor activity, sequence-specific DNA binding);GO:0030154(cell differentiation);GO:0001227(transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding);GO:0006357(regulation of transcription from RNA polymerase II promoter)","NA","NA","NA","ETS variant 3 like [Source:HGNC Symbol;Acc:HGNC:33834]",{"v":0.100809,"d":"0.10"},{"v":0.012877,"d":"0.01"},{"v":7.8286091480935,"d":"7.83"},{"v":2.96875601717349,"d":"2.97"},1,1,"up","no"]
["ENSG00000255394","C8orf49","ENST00000525043;ENST00000625198","NA","NA","NA","NA","chromosome 8 open reading frame 49 [Source:HGNC Symbol;Acc:HGNC:32200]",0,0,1,0,1,1,"no","no"]
["ENSG00000242083","AC068620.1","ENST00000470544","NA","NA","NA","NA",null,0,{"v":0.021751,"d":"0.02"},"-inf","-inf",1,1,"down","no"]
["MSTRG.15285","AC233300.1","ENST00000624323","NA","NA","NA","NA",null,0,{"v":0.062291,"d":"0.06"},"-inf","-inf",1,1,"down","no"]
["MSTRG.15472","FMR1-IT1","ENST00000441414","NA","NA","NA","NA","FMR1 intronic transcript 1 [Source:HGNC Symbol;Acc:HGNC:41333]",{"v":0.977673,"d":"0.98"},{"v":0.226088,"d":"0.23"},{"v":4.32430292629419,"d":"4.32"},{"v":2.11246759036086,"d":"2.11"},1,1,"up","no"]
["MSTRG.9385","KLF7-IT1","ENST00000428777","NA","NA","NA","NA","KLF7 intronic transcript 1 [Source:HGNC Symbol;Acc:HGNC:41355]",{"v":0.104055,"d":"0.10"},{"v":0.188843,"d":"0.19"},{"v":0.551013275578126,"d":"0.55"},{"v":-0.859841016780579,"d":"-0.86"},1,1,"down","no"]
["ENSG00000162494","LRRC38","ENST00000376085","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0006811(ion transport);GO:0071805(potassium ion transmembrane transport);GO:0005886(plasma membrane);GO:0005615(extracellular space);GO:0005887(integral component of plasma membrane);GO:0044325(ion channel binding);GO:0007409(axonogenesis);GO:0005578(proteinaceous extracellular matrix);GO:0005249(voltage-gated potassium channel activity);GO:0008076(voltage-gated potassium channel complex);GO:0099104(potassium channel activator activity);GO:1903818(positive regulation of voltage-gated potassium channel activity)","NA","NA","NA","leucine rich repeat containing 38 [Source:HGNC Symbol;Acc:HGNC:27005]",0,0,1,0,1,1,"no","no"]
["ENSG00000276166","AC092118.2","ENST00000613495","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000109851","DBX1","ENST00000524983","GO:0005634(nucleus);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0043565(sequence-specific DNA binding);GO:0007275(multicellular organism development);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0021521(ventral spinal cord interneuron specification)","NA","NA","NA","developing brain homeobox 1 [Source:HGNC Symbol;Acc:HGNC:33185]",0,0,1,0,1,1,"no","no"]
["ENSG00000198829","SUCNR1","ENST00000362032","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0004930(G-protein coupled receptor activity);GO:0007186(G-protein coupled receptor signaling pathway);GO:0005886(plasma membrane);GO:0004871(signal transducer activity);GO:0007165(signal transduction);GO:0008150(biological_process);GO:0070062(extracellular exosome)","04024(cAMP signaling pathway)","K10042","NA","succinate receptor 1 [Source:HGNC Symbol;Acc:HGNC:4542]",{"v":0.139714,"d":"0.14"},{"v":0.088873,"d":"0.09"},{"v":1.57206350635176,"d":"1.57"},{"v":0.65265949905208,"d":"0.65"},1,1,"up","no"]
["ENSG00000211785","TRAV12-1","ENST00000390433","NA","NA","NA","NA","T-cell receptor alpha variable 12-1 [Source:HGNC Symbol;Acc:HGNC:12105]",{"v":3.038816,"d":"3.04"},0,"inf","inf",1,1,"up","no"]
["ENSG00000223825","DAZAP2P1","ENST00000475212","NA","NA","NA","NA","DAZ associated protein 2 pseudogene 1 [Source:HGNC Symbol;Acc:HGNC:43869]",0,0,1,0,1,1,"no","no"]
["ENSG00000135638","EMX1","ENST00000258106;ENST00000394111","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005730(nucleolus);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0043565(sequence-specific DNA binding);GO:0007275(multicellular organism development);GO:0005515(protein binding);GO:0001701(in utero embryonic development);GO:0007420(brain development);GO:0009791(post-embryonic development);GO:0021537(telencephalon development);GO:0021796(cerebral cortex regionalization);GO:0021895(cerebral cortex neuron differentiation);GO:0021987(cerebral cortex development);GO:0030182(neuron differentiation);GO:0042493(response to drug);GO:0048854(brain morphogenesis);GO:0048872(homeostasis of number of cells);GO:0060019(radial glial cell differentiation);GO:0060563(neuroepithelial cell differentiation);GO:0070445(regulation of oligodendrocyte progenitor proliferation);GO:1990138(neuron projection extension);GO:1990138(neuron projection extension)","NA","NA","NA","empty spiracles homeobox 1 [Source:HGNC Symbol;Acc:HGNC:3340]",0,0,1,0,1,1,"no","no"]
["ENSG00000279488","AC004623.1","ENST00000624592","NA","NA","NA","NA",null,0,{"v":0.051844,"d":"0.05"},"-inf","-inf",1,1,"down","no"]
["ENSG00000179799","OR7E22P","ENST00000478335","NA","NA","NA","NA","olfactory receptor family 7 subfamily E member 22 pseudogene [Source:HGNC Symbol;Acc:HGNC:8394]",0,0,1,0,1,1,"no","no"]
["ENSG00000233871","DLG5-AS1","ENST00000449852","NA","NA","NA","NA","DLG5 antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:45109]",0,{"v":0.020814718609407,"d":"0.02"},"-inf","-inf",1,1,"down","no"]
["ENSG00000250980","AC113155.1","ENST00000511141","NA","NA","NA","NA",null,{"v":0.069076,"d":"0.07"},0,"inf","inf",1,1,"up","no"]
["ENSG00000236114","AL450326.2","ENST00000421913","NA","NA","NA","NA",null,{"v":0.080864,"d":"0.08"},0,"inf","inf",1,1,"up","no"]
["MSTRG.9053","AC017002.3","ENST00000627971;ENST00000455309","NA","NA","NA","NA",null,{"v":0.0047485455568054,"d":"0.00"},{"v":0.079508842519685,"d":"0.08"},{"v":0.0597234899455333,"d":"0.06"},{"v":-4.06555771787222,"d":"-4.07"},1,1,"down","no"]
["ENSG00000283175","AC007920.2","ENST00000636210","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000284439","AC106774.9","ENST00000638668","GO:0005634(nucleus);GO:0046982(protein heterodimerization activity);GO:0006367(transcription initiation from RNA polymerase II promoter)","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["MSTRG.12924","ZBTB12","ENST00000375527","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding)","NA","NA","NA","zinc finger and BTB domain containing 12 [Source:HGNC Symbol;Acc:HGNC:19066]",{"v":0.309572,"d":"0.31"},{"v":0.189996,"d":"0.19"},{"v":1.62936061811828,"d":"1.63"},{"v":0.704305943576858,"d":"0.70"},1,1,"up","no"]
["ENSG00000268945","AC010422.2","ENST00000593554","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000229425","AJ009632.2","ENST00000634708;ENST00000634644","NA","NA","NA","NA",null,{"v":0.00594117156917571,"d":"0.01"},{"v":0.00319031305223129,"d":"0.00"},{"v":1.86225347541379,"d":"1.86"},{"v":0.897049454655063,"d":"0.90"},1,1,"up","no"]
["MSTRG.14828","AUH","MSTRG.14828.1","NA","NA","NA","NA",null,{"v":2.13735,"d":"2.14"},{"v":2.739895,"d":"2.74"},{"v":0.780084638279934,"d":"0.78"},{"v":-0.358297431678829,"d":"-0.36"},1,1,"down","no"]
["ENSG00000256381","AC005832.1","ENST00000544380","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000196390","AC116337.1","ENST00000509680","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000253955","AC008663.2","ENST00000517299","NA","NA","NA","NA",null,{"v":0.0780459107498341,"d":"0.08"},{"v":0.0250483891838089,"d":"0.03"},{"v":3.11580557843945,"d":"3.12"},{"v":1.63960521421724,"d":"1.64"},1,1,"up","no"]
["MSTRG.5536","AC009065.4","ENST00000562838;ENST00000567888;ENST00000563734","NA","NA","NA","NA",null,0,{"v":0.103860793877551,"d":"0.10"},"-inf","-inf",1,1,"down","no"]
["ENSG00000120952","PRAMEF2","ENST00000240189","GO:0043066(negative regulation of apoptotic process);GO:0008284(positive regulation of cell proliferation);GO:0045596(negative regulation of cell differentiation);GO:0045892(negative regulation of transcription, DNA-templated)","NA","NA","NA","PRAME family member 2 [Source:HGNC Symbol;Acc:HGNC:28841]",0,0,1,0,1,1,"no","no"]
["MSTRG.223","LINC01635","ENST00000455966;ENST00000635097","NA","NA","NA","NA","long intergenic non-protein coding RNA 1635 [Source:HGNC Symbol;Acc:HGNC:52422]",0,{"v":0.0331330284191829,"d":"0.03"},"-inf","-inf",1,1,"down","no"]
["MSTRG.14801","RPL24P8","ENST00000446071","NA","NA","NA","NA","ribosomal protein L24 pseudogene 8 [Source:HGNC Symbol;Acc:HGNC:36409]",0,{"v":0.053683,"d":"0.05"},"-inf","-inf",1,1,"down","no"]
["ENSG00000143473","KCNH1","ENST00000271751","GO:0005622(intracellular);GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0055085(transmembrane transport);GO:0005216(ion channel activity);GO:0006811(ion transport);GO:0005244(voltage-gated ion channel activity);GO:0005249(voltage-gated potassium channel activity);GO:0005267(potassium channel activity);GO:0006813(potassium ion transport);GO:0034765(regulation of ion transmembrane transport);GO:0071805(potassium ion transmembrane transport);GO:0023014(signal transduction by protein phosphorylation);GO:0000155(phosphorelay sensor kinase activity);GO:0000160(phosphorelay signal transduction system);GO:0005634(nucleus);GO:0043231(intracellular membrane-bounded organelle);GO:0005886(plasma membrane);GO:0042995(cell projection);GO:0005515(protein binding);GO:0030054(cell junction);GO:0045202(synapse);GO:0045211(postsynaptic membrane);GO:0048015(phosphatidylinositol-mediated signaling);GO:0030425(dendrite);GO:0008289(lipid binding);GO:0005516(calmodulin binding);GO:0005887(integral component of plasma membrane);GO:0005768(endosome);GO:0030424(axon);GO:0043204(perikaryon);GO:0005637(nuclear inner membrane);GO:0014069(postsynaptic density);GO:0031901(early endosome membrane);GO:0042127(regulation of cell proliferation);GO:0008076(voltage-gated potassium channel complex);GO:0042734(presynaptic membrane);GO:0007520(myoblast fusion);GO:0071277(cellular response to calcium ion);GO:0042391(regulation of membrane potential);GO:0005251(delayed rectifier potassium channel activity);GO:1902936(phosphatidylinositol bisphosphate binding);GO:0034220(ion transmembrane transport)","NA","NA","NA","potassium voltage-gated channel subfamily H member 1 [Source:HGNC Symbol;Acc:HGNC:6250]",0,0,1,0,1,1,"no","no"]
["ENSG00000205420","KRT6A","ENST00000330722","GO:0005634(nucleus);GO:0016020(membrane);GO:0005198(structural molecule activity);GO:0005515(protein binding);GO:0007010(cytoskeleton organization);GO:0005882(intermediate filament);GO:0030154(cell differentiation);GO:0045095(keratin filament);GO:0005200(structural constituent of cytoskeleton);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0031424(keratinization);GO:0050830(defense response to Gram-positive bacterium);GO:0061844(antimicrobial humoral immune response mediated by antimicrobial peptide);GO:0008284(positive regulation of cell proliferation);GO:0042060(wound healing);GO:0070268(cornification);GO:0001899(negative regulation of cytolysis by symbiont of host cells);GO:0002009(morphogenesis of an epithelium);GO:0051801(cytolysis in other organism involved in symbiotic interaction);GO:2000536(negative regulation of entry of bacterium into host cell)","NA","NA","NA","keratin 6A [Source:HGNC Symbol;Acc:HGNC:6443]",{"v":0.0179616700819672,"d":"0.02"},{"v":0.0170930532786885,"d":"0.02"},{"v":1.05081694821379,"d":"1.05"},{"v":0.0715113744334471,"d":"0.07"},1,1,"up","no"]
["MSTRG.4673","AL157871.5","ENST00000555212","NA","NA","NA","NA",null,{"v":0.02343,"d":"0.02"},{"v":0.179828,"d":"0.18"},{"v":0.130291167115243,"d":"0.13"},{"v":-2.94018881290746,"d":"-2.94"},1,1,"down","no"]
["ENSG00000253903","AC090150.2","ENST00000521869","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["MSTRG.14283","TUBBP1","ENST00000248151;ENST00000518096","NA","NA","NA","NA","tubulin beta pseudogene 1 [Source:HGNC Symbol;Acc:HGNC:12414]",{"v":0.59361334872418,"d":"0.59"},{"v":0.299407094775213,"d":"0.30"},{"v":1.98262953377858,"d":"1.98"},{"v":0.987415126527028,"d":"0.99"},1,1,"up","no"]
["ENSG00000251685","UGT2B27P","ENST00000505092","NA","NA","NA","NA","UDP glucuronosyltransferase family 2 member B27, pseudogene [Source:HGNC Symbol;Acc:HGNC:12551]",0,0,1,0,1,1,"no","no"]
["MSTRG.5641","AC012173.1","ENST00000567942","NA","NA","NA","NA",null,{"v":0.000409,"d":"0.00"},{"v":0.048492,"d":"0.05"},{"v":0.008434380928813,"d":"0.01"},{"v":-6.88950210396287,"d":"-6.89"},1,1,"down","no"]
["ENSG00000264066","AC024267.1","ENST00000582320","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000227695","DNMBP-AS1","ENST00000427093","NA","NA","NA","NA","DNMBP antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:20431]",{"v":0.0129509948630137,"d":"0.01"},0,"inf","inf",1,1,"up","no"]
["ENSG00000214359","RPL18P10","ENST00000425606","NA","NA","NA","NA","ribosomal protein L18 pseudogene 10 [Source:HGNC Symbol;Acc:HGNC:35957]",{"v":0.197471,"d":"0.20"},0,"inf","inf",1,1,"up","no"]
["ENSG00000233003","CICP26","ENST00000425003","NA","NA","NA","NA","capicua transcriptional repressor pseudogene 26 [Source:HGNC Symbol;Acc:HGNC:48834]",{"v":0.010139,"d":"0.01"},{"v":0.020789,"d":"0.02"},{"v":0.487709846553466,"d":"0.49"},{"v":-1.03590499511876,"d":"-1.04"},1,1,"down","no"]
["ENSG00000279792","AC015909.5","ENST00000624336","NA","NA","NA","NA",null,{"v":0.093613,"d":"0.09"},0,"inf","inf",1,1,"up","no"]
["ENSG00000258234","AC024257.1","ENST00000547523","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000244474","UGT1A4","ENST00000373409","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016740(transferase activity);GO:0016757(transferase activity, transferring glycosyl groups);GO:0008152(metabolic process);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0042803(protein homodimerization activity);GO:0016758(transferase activity, transferring hexosyl groups);GO:0015020(glucuronosyltransferase activity);GO:0043231(intracellular membrane-bounded organelle);GO:0046982(protein heterodimerization activity);GO:0052695(cellular glucuronidation);GO:0042167(heme catabolic process);GO:0052696(flavonoid glucuronidation);GO:0052697(xenobiotic glucuronidation);GO:0006789(bilirubin conjugation)","00040(Pentose and glucuronate interconversions);00053(Ascorbate and aldarate metabolism);00140(Steroid hormone biosynthesis);00830(Retinol metabolism);00860(Porphyrin and chlorophyll metabolism);00980(Metabolism of xenobiotics by cytochrome P450);00982(Drug metabolism - cytochrome P450);00983(Drug metabolism - other enzymes);05204(Chemical carcinogenesis)","K00699","EC:2.4.1.17","UDP glucuronosyltransferase family 1 member A4 [Source:HGNC Symbol;Acc:HGNC:12536]",0,{"v":0.020179641554322,"d":"0.02"},"-inf","-inf",1,1,"down","no"]
["ENSG00000143590","EFNA3","ENST00000368408","GO:0016020(membrane);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0031225(anchored component of membrane);GO:0046875(ephrin receptor binding);GO:0048013(ephrin receptor signaling pathway);GO:0005887(integral component of plasma membrane);GO:0007411(axon guidance);GO:0007267(cell-cell signaling);GO:1902961(positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process);GO:0005005(transmembrane-ephrin receptor activity)","04014(Ras signaling pathway);04015(Rap1 signaling pathway);04010(MAPK signaling pathway);04151(PI3K-Akt signaling pathway);04360(Axon guidance);05206(MicroRNAs in cancer)","K05462","NA","ephrin A3 [Source:HGNC Symbol;Acc:HGNC:3223]",{"v":0.400947199580932,"d":"0.40"},{"v":0.330552132006286,"d":"0.33"},{"v":1.21296207393183,"d":"1.21"},{"v":0.27853444196224,"d":"0.28"},1,1,"up","no"]
["MSTRG.7946","AC024075.3","ENST00000601040;ENST00000601687","NA","NA","NA","NA",null,{"v":0.252795986866792,"d":"0.25"},{"v":0.0536296566604128,"d":"0.05"},{"v":4.71373494832376,"d":"4.71"},{"v":2.2368706386285,"d":"2.24"},1,1,"up","no"]
["ENSG00000134376","CRB1","ENST00000535699;ENST00000484075;ENST00000475659;ENST00000367397","GO:0005622(intracellular);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005509(calcium ion binding);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0016324(apical plasma membrane);GO:0007267(cell-cell signaling);GO:0006611(protein export from nucleus);GO:0007163(establishment or maintenance of cell polarity);GO:0007009(plasma membrane organization);GO:0042462(eye photoreceptor cell development);GO:0061024(membrane organization);GO:0005902(microvillus);GO:0005902(microvillus)","04390(Hippo signaling pathway);04390(Hippo signaling pathway)","K16681","NA","crumbs 1, cell polarity complex component [Source:HGNC Symbol;Acc:HGNC:2343]",{"v":0.00819961740429211,"d":"0.01"},{"v":0.00800117349264995,"d":"0.01"},{"v":1.02480185085656,"d":"1.02"},{"v":0.0353449863924784,"d":"0.04"},1,1,"up","no"]
["ENSG00000169836","TACR3","ENST00000304883","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0004930(G-protein coupled receptor activity);GO:0007186(G-protein coupled receptor signaling pathway);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0004871(signal transducer activity);GO:0007165(signal transduction);GO:0004995(tachykinin receptor activity);GO:0005887(integral component of plasma membrane);GO:0007217(tachykinin receptor signaling pathway);GO:0007568(aging);GO:0010460(positive regulation of heart rate);GO:0032355(response to estradiol);GO:0042053(regulation of dopamine metabolic process);GO:0042220(response to cocaine);GO:0042538(hyperosmotic salinity response);GO:0043278(response to morphine);GO:0045777(positive regulation of blood pressure);GO:0060259(regulation of feeding behavior);GO:0070474(positive regulation of uterine smooth muscle contraction);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0032590(dendrite membrane);GO:0032809(neuronal cell body membrane)","04020(Calcium signaling pathway);04080(Neuroactive ligand-receptor interaction)","K04224","NA","tachykinin receptor 3 [Source:HGNC Symbol;Acc:HGNC:11528]",0,0,1,0,1,1,"no","no"]
["MSTRG.12877","APOM","ENST00000375920;ENST00000375918;ENST00000375916","GO:0042632(cholesterol homeostasis);GO:0006810(transport);GO:0005576(extracellular region);GO:0006869(lipid transport);GO:0098869(cellular oxidant detoxification);GO:0070062(extracellular exosome);GO:0005887(integral component of plasma membrane);GO:0034364(high-density lipoprotein particle);GO:0001523(retinoid metabolic process);GO:0034361(very-low-density lipoprotein particle);GO:0033344(cholesterol efflux);GO:0005319(lipid transporter activity);GO:0005543(phospholipid binding);GO:0016209(antioxidant activity);GO:0034375(high-density lipoprotein particle remodeling);GO:0034380(high-density lipoprotein particle assembly);GO:0034384(high-density lipoprotein particle clearance);GO:0034445(negative regulation of plasma lipoprotein oxidation);GO:0043691(reverse cholesterol transport);GO:0034362(low-density lipoprotein particle);GO:0034365(discoidal high-density lipoprotein particle);GO:0034366(spherical high-density lipoprotein particle);GO:0009749(response to glucose);GO:0042157(lipoprotein metabolic process);GO:0005615(extracellular space);GO:0005615(extracellular space)","NA","NA","NA","apolipoprotein M [Source:HGNC Symbol;Acc:HGNC:13916]",{"v":0.53795826746988,"d":"0.54"},{"v":0.422913672891566,"d":"0.42"},{"v":1.27202855323103,"d":"1.27"},{"v":0.347131055168235,"d":"0.35"},1,1,"up","no"]
["ENSG00000155249","OR4K1","ENST00000285600","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0004930(G-protein coupled receptor activity);GO:0007186(G-protein coupled receptor signaling pathway);GO:0005886(plasma membrane);GO:0004871(signal transducer activity);GO:0007165(signal transduction);GO:0004984(olfactory receptor activity);GO:0007608(sensory perception of smell);GO:0050896(response to stimulus);GO:0050911(detection of chemical stimulus involved in sensory perception of smell);GO:0004888(transmembrane signaling receptor activity);GO:0050907(detection of chemical stimulus involved in sensory perception)","04740(Olfactory transduction)","K04257","NA","olfactory receptor family 4 subfamily K member 1 [Source:HGNC Symbol;Acc:HGNC:14726]",0,0,1,0,1,1,"no","no"]
["ENSG00000197599","CCDC154","ENST00000463299;ENST00000409671;ENST00000389176;ENST00000483702","GO:0005768(endosome);GO:0005769(early endosome);GO:0005769(early endosome)","NA","NA","NA","coiled-coil domain containing 154 [Source:HGNC Symbol;Acc:HGNC:34454]",{"v":0.0973709339691856,"d":"0.10"},{"v":0.182849519442406,"d":"0.18"},{"v":0.532519496174315,"d":"0.53"},{"v":-0.909093749794686,"d":"-0.91"},1,1,"down","no"]
["ENSG00000204702","OR2J1","ENST00000377171","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0004930(G-protein coupled receptor activity);GO:0007186(G-protein coupled receptor signaling pathway);GO:0005886(plasma membrane);GO:0004871(signal transducer activity);GO:0007165(signal transduction);GO:0004984(olfactory receptor activity);GO:0007608(sensory perception of smell);GO:0050896(response to stimulus);GO:0050911(detection of chemical stimulus involved in sensory perception of smell)","NA","NA","NA","olfactory receptor family 2 subfamily J member 1 (gene/pseudogene) [Source:HGNC Symbol;Acc:HGNC:8259]",0,0,1,0,1,1,"no","no"]
["ENSG00000188803","SHISA6","ENST00000441885;ENST00000343478","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0048172(regulation of short-term neuronal synaptic plasticity);GO:0032281(AMPA glutamate receptor complex);GO:0045202(synapse);GO:0045202(synapse)","NA","NA","NA","shisa family member 6 [Source:HGNC Symbol;Acc:HGNC:34491]",0,0,1,0,1,1,"no","no"]
["ENSG00000125363","AMELX","ENST00000380712","GO:0007275(multicellular organism development);GO:0005576(extracellular region);GO:0005578(proteinaceous extracellular matrix);GO:0031214(biomineral tissue development);GO:0044267(cellular protein metabolic process);GO:0043687(post-translational protein modification);GO:0005515(protein binding);GO:0009986(cell surface);GO:0005788(endoplasmic reticulum lumen);GO:0042802(identical protein binding);GO:0001837(epithelial to mesenchymal transition);GO:0007165(signal transduction);GO:0008083(growth factor activity);GO:0032967(positive regulation of collagen biosynthetic process);GO:0042127(regulation of cell proliferation);GO:0001649(osteoblast differentiation);GO:0007155(cell adhesion);GO:0042475(odontogenesis of dentin-containing tooth);GO:0002062(chondrocyte differentiation);GO:0030345(structural constituent of tooth enamel);GO:0046848(hydroxyapatite binding);GO:0034505(tooth mineralization);GO:0070166(enamel mineralization);GO:0070172(positive regulation of tooth mineralization)","NA","NA","NA","amelogenin, X-linked [Source:HGNC Symbol;Acc:HGNC:461]",0,0,1,0,1,1,"no","no"]
["ENSG00000219773","RPSAP45","ENST00000401872","NA","NA","NA","NA","ribosomal protein SA pseudogene 45 [Source:HGNC Symbol;Acc:HGNC:35857]",{"v":0.030389,"d":"0.03"},{"v":0.439028,"d":"0.44"},{"v":0.0692188197563709,"d":"0.07"},{"v":-3.85269184732001,"d":"-3.85"},1,1,"down","no"]
["MSTRG.10741","RARB","ENST00000330688","GO:0005634(nucleus);GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0043565(sequence-specific DNA binding);GO:0003707(steroid hormone receptor activity);GO:0043401(steroid hormone mediated signaling pathway);GO:0003708(retinoic acid receptor activity);GO:0048384(retinoic acid receptor signaling pathway);GO:0005737(cytoplasm);GO:0005654(nucleoplasm);GO:0007165(signal transduction);GO:0006367(transcription initiation from RNA polymerase II promoter);GO:0048566(embryonic digestive tract development);GO:0000977(RNA polymerase II regulatory region sequence-specific DNA binding);GO:0008144(drug binding);GO:0032403(protein complex binding);GO:0046965(retinoid X receptor binding);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0001657(ureteric bud development);GO:0002068(glandular epithelial cell development);GO:0003148(outflow tract septum morphogenesis);GO:0003406(retinal pigment epithelium development);GO:0003417(growth plate cartilage development);GO:0008284(positive regulation of cell proliferation);GO:0008285(negative regulation of cell proliferation);GO:0021756(striatum development);GO:0022008(neurogenesis);GO:0031641(regulation of myelination);GO:0032331(negative regulation of chondrocyte differentiation);GO:0035116(embryonic hindlimb morphogenesis);GO:0035264(multicellular organism growth);GO:0043065(positive regulation of apoptotic process);GO:0043066(negative regulation of apoptotic process);GO:0043068(positive regulation of programmed cell death);GO:0045666(positive regulation of neuron differentiation);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0048048(embryonic eye morphogenesis);GO:0055012(ventricular cardiac muscle cell differentiation);GO:0060041(retina development in camera-type eye);GO:0060348(bone development);GO:0061037(negative regulation of cartilage development)","05200(Pathways in cancer);05226(Gastric cancer);05222(Small cell lung cancer);05223(Non-small cell lung cancer)","K08528","NA","retinoic acid receptor beta [Source:HGNC Symbol;Acc:HGNC:9865]",{"v":0.0143680865566676,"d":"0.01"},{"v":0.0275316029212875,"d":"0.03"},{"v":0.521876136225914,"d":"0.52"},{"v":-0.938220661382016,"d":"-0.94"},1,1,"down","no"]
["MSTRG.12814","DDX39BP2","ENST00000453923","NA","NA","NA","NA","DEAD-box helicase 39B pseudogene 2 [Source:HGNC Symbol;Acc:HGNC:33461]",{"v":0.118895,"d":"0.12"},0,"inf","inf",1,1,"up","no"]
["ENSG00000182330","PRAMEF8","ENST00000357367","GO:0043066(negative regulation of apoptotic process);GO:0008284(positive regulation of cell proliferation);GO:0045596(negative regulation of cell differentiation);GO:0045892(negative regulation of transcription, DNA-templated)","NA","NA","NA","PRAME family member 8 [Source:HGNC Symbol;Acc:HGNC:24074]",0,0,1,0,1,1,"no","no"]
["ENSG00000197927","C2orf27A","ENST00000463645;ENST00000481510;ENST00000624391;ENST00000623058","NA","NA","NA","NA","chromosome 2 open reading frame 27A [Source:HGNC Symbol;Acc:HGNC:25077]",{"v":0.180447941153546,"d":"0.18"},{"v":0.17751533826968,"d":"0.18"},{"v":1.01652027882464,"d":"1.02"},{"v":0.0236389961643738,"d":"0.02"},1,1,"up","no"]
["MSTRG.14597","PEG13","ENST00000631594","NA","NA","NA","NA","paternally expressed 13 [Source:HGNC Symbol;Acc:HGNC:19969]",0,{"v":0.309585,"d":"0.31"},"-inf","-inf",1,1,"down","no"]
["ENSG00000272078","AL139423.1","ENST00000606802","NA","NA","NA","NA",null,{"v":0.074094,"d":"0.07"},{"v":0.058601,"d":"0.06"},{"v":1.26438115390522,"d":"1.26"},{"v":0.338431436582425,"d":"0.34"},1,1,"up","no"]
["ENSG00000177243","DEFB103B","ENST00000318124","GO:0005576(extracellular region);GO:0006952(defense response);GO:0042742(defense response to bacterium);GO:0050829(defense response to Gram-negative bacterium);GO:0050830(defense response to Gram-positive bacterium);GO:0019730(antimicrobial humoral response);GO:0005796(Golgi lumen);GO:0031640(killing of cells of other organism);GO:0005615(extracellular space)","NA","NA","NA","defensin beta 103B [Source:HGNC Symbol;Acc:HGNC:31702]",0,0,1,0,1,1,"no","no"]
["ENSG00000158482","SNX29P1","ENST00000548357","NA","NA","NA","NA","sorting nexin 29 pseudogene 1 [Source:HGNC Symbol;Acc:HGNC:31913]",{"v":0.670168,"d":"0.67"},{"v":0.25269,"d":"0.25"},{"v":2.65213502710831,"d":"2.65"},{"v":1.40715422868598,"d":"1.41"},1,1,"up","no"]
["ENSG00000197905","TEAD4","ENST00000359864","GO:0005634(nucleus);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0035329(hippo signaling);GO:0005654(nucleoplasm);GO:0005515(protein binding);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0005667(transcription factor complex);GO:0006367(transcription initiation from RNA polymerase II promoter);GO:0001501(skeletal system development);GO:0043565(sequence-specific DNA binding);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0007517(muscle organ development);GO:0044212(transcription regulatory region DNA binding);GO:0001085(RNA polymerase II transcription factor binding);GO:0048568(embryonic organ development)","04390(Hippo signaling pathway);04392(Hippo signaling pathway - multiple species)","K09448","NA","TEA domain transcription factor 4 [Source:HGNC Symbol;Acc:HGNC:11717]",0,{"v":0.0223991945422535,"d":"0.02"},"-inf","-inf",1,1,"down","no"]
["MSTRG.7754","PCP2","ENST00000598935;ENST00000311069","GO:0030695(GTPase regulator activity);GO:0050790(regulation of catalytic activity);GO:0050790(regulation of catalytic activity)","NA","NA","NA","Purkinje cell protein 2 [Source:HGNC Symbol;Acc:HGNC:30209]",{"v":0.861058488110138,"d":"0.86"},{"v":1.06946546433041,"d":"1.07"},{"v":0.805129774479669,"d":"0.81"},{"v":-0.312706752767494,"d":"-0.31"},1,1,"down","no"]
["ENSG00000216990","HSPD1P10","ENST00000404829","NA","NA","NA","NA","heat shock protein family D (Hsp60) member 1 pseudogene 10 [Source:HGNC Symbol;Acc:HGNC:35131]",0,{"v":0.030365,"d":"0.03"},"-inf","-inf",1,1,"down","no"]
["ENSG00000226455","AL121787.1","ENST00000445838;ENST00000413986","NA","NA","NA","NA",null,{"v":0.0414924192513369,"d":"0.04"},0,"inf","inf",1,1,"up","no"]
["ENSG00000180090","OR3A1","ENST00000615105","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0004930(G-protein coupled receptor activity);GO:0007186(G-protein coupled receptor signaling pathway);GO:0005886(plasma membrane);GO:0004871(signal transducer activity);GO:0007165(signal transduction);GO:0004984(olfactory receptor activity);GO:0007608(sensory perception of smell);GO:0050896(response to stimulus);GO:0050911(detection of chemical stimulus involved in sensory perception of smell)","04740(Olfactory transduction)","K04257","NA","olfactory receptor family 3 subfamily A member 1 [Source:HGNC Symbol;Acc:HGNC:8282]",0,0,1,0,1,1,"no","no"]
["MSTRG.141","AL691449.1","ENST00000426570","NA","NA","NA","NA",null,{"v":0.063088,"d":"0.06"},0,"inf","inf",1,1,"up","no"]
["ENSG00000274583","FAM74A4","ENST00000621724","NA","NA","NA","NA","family with sequence similarity 74 member A4 [Source:HGNC Symbol;Acc:HGNC:32032]",0,0,1,0,1,1,"no","no"]
["ENSG00000101210","EEF1A2","ENST00000217182","GO:0005737(cytoplasm);GO:0006412(translation);GO:0005525(GTP binding);GO:0000166(nucleotide binding);GO:0003924(GTPase activity);GO:0005515(protein binding);GO:0003746(translation elongation factor activity);GO:0006414(translational elongation);GO:0019901(protein kinase binding);GO:0008135(translation factor activity, RNA binding);GO:1904714(regulation of chaperone-mediated autophagy);GO:0098574(cytoplasmic side of lysosomal membrane);GO:0090218(positive regulation of lipid kinase activity);GO:0010035(response to inorganic substance);GO:0043065(positive regulation of apoptotic process);GO:0051602(response to electrical stimulus);GO:0005853(eukaryotic translation elongation factor 1 complex);GO:0043025(neuronal cell body);GO:0043209(myelin sheath)","03013(RNA transport);05134(Legionellosis)","K03231","NA","eukaryotic translation elongation factor 1 alpha 2 [Source:HGNC Symbol;Acc:HGNC:3192]",{"v":0.052873,"d":"0.05"},{"v":0.100051,"d":"0.10"},{"v":0.528460485152572,"d":"0.53"},{"v":-0.920132494624176,"d":"-0.92"},1,1,"down","no"]
["ENSG00000282798","AC008993.2","ENST00000631744","NA","NA","NA","NA",null,{"v":0.09122,"d":"0.09"},{"v":0.031571,"d":"0.03"},{"v":2.88936048905641,"d":"2.89"},{"v":1.5307502119777,"d":"1.53"},1,1,"up","no"]
["ENSG00000233295","FAM90A20P","ENST00000528221","NA","NA","NA","NA","family with sequence similarity 90 member A20, pseudogene [Source:HGNC Symbol;Acc:HGNC:32268]",0,0,1,0,1,1,"no","no"]
["ENSG00000088882","CPXM1","ENST00000380605","GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0016787(hydrolase activity);GO:0008233(peptidase activity);GO:0006508(proteolysis);GO:0005576(extracellular region);GO:0004180(carboxypeptidase activity);GO:0008237(metallopeptidase activity);GO:0005615(extracellular space)","NA","NA","NA","carboxypeptidase X, M14 family member 1 [Source:HGNC Symbol;Acc:HGNC:15771]",{"v":0.116188,"d":"0.12"},{"v":0.383055,"d":"0.38"},{"v":0.303319366670583,"d":"0.30"},{"v":-1.72109047919494,"d":"-1.72"},1,1,"down","no"]
["ENSG00000171658","NMRAL2P","ENST00000423298","NA","NA","NA","NA","NmrA like redox sensor 2, pseudogene [Source:HGNC Symbol;Acc:HGNC:52332]",{"v":0.0404263744292237,"d":"0.04"},0,"inf","inf",1,1,"up","no"]
["ENSG00000271150","AC008745.1","ENST00000604064","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000234345","AC234782.4","ENST00000417646","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000257175","CR383656.2","ENST00000548656","NA","NA","NA","NA",null,{"v":0.011705,"d":"0.01"},0,"inf","inf",1,1,"up","no"]
["ENSG00000257545","AC079385.1","ENST00000549203;ENST00000551505","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000177990","DPY19L2","ENST00000324472;ENST00000439061;ENST00000536494","GO:0005634(nucleus);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016740(transferase activity);GO:0016757(transferase activity, transferring glycosyl groups);GO:0007275(multicellular organism development);GO:0030154(cell differentiation);GO:0007286(spermatid development);GO:0007283(spermatogenesis);GO:0000030(mannosyltransferase activity);GO:0005637(nuclear inner membrane);GO:0018406(protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan);GO:0018406(protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan)","NA","NA","NA","dpy-19 like 2 [Source:HGNC Symbol;Acc:HGNC:19414]",{"v":0.0292840216082182,"d":"0.03"},{"v":0.0255815756287637,"d":"0.03"},{"v":1.14473095923347,"d":"1.14"},{"v":0.195008568289112,"d":"0.20"},1,1,"up","no"]
["ENSG00000248121","SMURF2P1","ENST00000579301;ENST00000514992","NA","NA","NA","NA","SMAD specific E3 ubiquitin protein ligase 2 pseudogene 1 [Source:HGNC Symbol;Acc:HGNC:44402]",{"v":0.22345,"d":"0.22"},{"v":0.216452,"d":"0.22"},{"v":1.03233049359673,"d":"1.03"},{"v":0.0459049137287341,"d":"0.05"},1,1,"up","no"]
["ENSG00000212721","KRTAP4-11","ENST00000391413","GO:0005515(protein binding);GO:0005882(intermediate filament);GO:0045095(keratin filament);GO:0005829(cytosol);GO:0031424(keratinization)","NA","NA","NA","keratin associated protein 4-11 [Source:HGNC Symbol;Acc:HGNC:18911]",0,0,1,0,1,1,"no","no"]
["ENSG00000254714","AP006587.1","ENST00000534129","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["MSTRG.10546","SERHL","ENST00000455578;ENST00000359906","NA","NA","NA","NA","serine hydrolase-like (pseudogene) [Source:HGNC Symbol;Acc:HGNC:14408]",{"v":0.210611380022962,"d":"0.21"},{"v":0.132722398392652,"d":"0.13"},{"v":1.58685634507508,"d":"1.59"},{"v":0.666171529793462,"d":"0.67"},1,1,"up","no"]
["ENSG00000182450","KCNK4","ENST00000536690","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005244(voltage-gated ion channel activity);GO:0005267(potassium channel activity);GO:0006811(ion transport);GO:0006813(potassium ion transport);GO:0034765(regulation of ion transmembrane transport);GO:0071805(potassium ion transmembrane transport);GO:0005886(plasma membrane);GO:0005887(integral component of plasma membrane);GO:0030322(stabilization of membrane potential);GO:0034705(potassium channel complex);GO:0071260(cellular response to mechanical stimulus);GO:0071398(cellular response to fatty acid);GO:0097604(temperature-gated cation channel activity);GO:0019233(sensory perception of pain);GO:0071502(cellular response to temperature stimulus);GO:0022841(potassium ion leak channel activity);GO:0071469(cellular response to alkaline pH);GO:0050976(detection of mechanical stimulus involved in sensory perception of touch);GO:0098782(mechanically-gated potassium channel activity);GO:0050951(sensory perception of temperature stimulus);GO:0007613(memory)","NA","NA","NA","potassium two pore domain channel subfamily K member 4 [Source:HGNC Symbol;Acc:HGNC:6279]",0,0,1,0,1,1,"no","no"]
["MSTRG.5187","AC100830.2","ENST00000581636","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000213188","YBX1P4","ENST00000392794","NA","NA","NA","NA","Y-box binding protein 1 pseudogene 4 [Source:HGNC Symbol;Acc:HGNC:42425]",0,{"v":0.061734,"d":"0.06"},"-inf","-inf",1,1,"down","no"]
["ENSG00000258623","AL121820.1","ENST00000556919","NA","NA","NA","NA",null,{"v":0.150026,"d":"0.15"},{"v":0.347709,"d":"0.35"},{"v":0.431469993586591,"d":"0.43"},{"v":-1.21266786366177,"d":"-1.21"},1,1,"down","no"]
["ENSG00000198901","PRC1","ENST00000394249;ENST00000560914;ENST00000560605;ENST00000557763;ENST00000442656;ENST00000361188;ENST00000417173;ENST00000555745;ENST00000559811","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005654(nucleoplasm);GO:0051301(cell division);GO:0005886(plasma membrane);GO:0015630(microtubule cytoskeleton);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0007049(cell cycle);GO:0008017(microtubule binding);GO:0001578(microtubule bundle formation);GO:0005874(microtubule);GO:0000226(microtubule cytoskeleton organization);GO:0000922(spindle pole);GO:0005819(spindle);GO:0030496(midbody);GO:0000910(cytokinesis);GO:0005829(cytosol);GO:0019901(protein kinase binding);GO:0008284(positive regulation of cell proliferation);GO:0019894(kinesin binding);GO:0000022(mitotic spindle elongation);GO:0005876(spindle microtubule);GO:0070938(contractile ring);GO:0070938(contractile ring)","NA","NA","NA","protein regulator of cytokinesis 1 [Source:HGNC Symbol;Acc:HGNC:9341]",{"v":0.235631970678733,"d":"0.24"},{"v":0.130205918914027,"d":"0.13"},{"v":1.80968709137038,"d":"1.81"},{"v":0.855740265952712,"d":"0.86"},1,1,"up","no"]
["ENSG00000016082","ISL1","ENST00000230658","GO:0045766(positive regulation of angiogenesis);GO:0050728(negative regulation of inflammatory response);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0005737(cytoplasm);GO:0003151(outflow tract morphogenesis);GO:0005634(nucleus);GO:0032755(positive regulation of interleukin-6 production);GO:0046872(metal ion binding);GO:0005654(nucleoplasm);GO:0006355(regulation of transcription, DNA-templated);GO:0006366(transcription from RNA polymerase II promoter);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0043565(sequence-specific DNA binding);GO:0005515(protein binding);GO:0007275(multicellular organism development);GO:0030154(cell differentiation);GO:0060037(pharyngeal system development);GO:0032729(positive regulation of interferon-gamma production);GO:0032735(positive regulation of interleukin-12 production);GO:0032760(positive regulation of tumor necrosis factor production);GO:0043425(bHLH transcription factor binding);GO:0032024(positive regulation of insulin secretion);GO:0045597(positive regulation of cell differentiation);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0016922(ligand-dependent nuclear receptor binding);GO:0001102(RNA polymerase II activating transcription factor binding);GO:0055010(ventricular cardiac muscle tissue morphogenesis);GO:1990841(promoter-specific chromatin binding);GO:0003148(outflow tract septum morphogenesis);GO:0043524(negative regulation of neuron apoptotic process);GO:0033147(negative regulation of intracellular estrogen receptor signaling pathway);GO:0010575(positive regulation of vascular endothelial growth factor production);GO:0032725(positive regulation of granulocyte macrophage colony-stimulating factor production);GO:0071385(cellular response to glucocorticoid stimulus);GO:0032731(positive regulation of interleukin-1 beta production);GO:0003203(endocardial cushion morphogenesis);GO:0003139(secondary heart field specification);GO:0001105(RNA polymerase II transcription coactivator activity);GO:0030331(estrogen receptor binding);GO:0003215(cardiac right ventricle morphogenesis);GO:0060413(atrial septum morphogenesis);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:0001077(transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0001158(enhancer sequence-specific DNA binding);GO:0003682(chromatin binding);GO:0001755(neural crest cell migration);GO:0003007(heart morphogenesis);GO:0003266(regulation of secondary heart field cardioblast proliferation);GO:0007507(heart development);GO:0008284(positive regulation of cell proliferation);GO:0010468(regulation of gene expression);GO:0010718(positive regulation of epithelial to mesenchymal transition);GO:0021520(spinal cord motor neuron cell fate specification);GO:0021522(spinal cord motor neuron differentiation);GO:0021524(visceral motor neuron differentiation);GO:0021559(trigeminal nerve development);GO:0021983(pituitary gland development);GO:0030182(neuron differentiation);GO:0031016(pancreas development);GO:0031103(axon regeneration);GO:0031290(retinal ganglion cell axon guidance);GO:0032730(positive regulation of interleukin-1 alpha production);GO:0035066(positive regulation of histone acetylation);GO:0042531(positive regulation of tyrosine phosphorylation of STAT protein);GO:0043388(positive regulation of DNA binding);GO:0045665(negative regulation of neuron differentiation);GO:0048663(neuron fate commitment);GO:0048665(neuron fate specification);GO:0048762(mesenchymal cell differentiation);GO:0048880(sensory system development);GO:0048935(peripheral nervous system neuron development);GO:0048936(peripheral nervous system neuron axonogenesis);GO:0060379(cardiac muscle cell myoblast differentiation);GO:0060384(innervation);GO:0060913(cardiac cell fate determination);GO:0071657(positive regulation of granulocyte colony-stimulating factor production);GO:0090074(negative regulation of protein homodimerization activity);GO:0090090(negative regulation of canonical Wnt signaling pathway);GO:1901258(positive regulation of macrophage colony-stimulating factor production)","04550(Signaling pathways regulating pluripotency of stem cells)","K09370","NA","ISL LIM homeobox 1 [Source:HGNC Symbol;Acc:HGNC:6132]",0,0,1,0,1,1,"no","no"]
["MSTRG.6223","AC105429.1","ENST00000612833","NA","NA","NA","NA",null,0,{"v":0.012383,"d":"0.01"},"-inf","-inf",1,1,"down","no"]
["ENSG00000253522","MIR3142HG","ENST00000517927","NA","NA","NA","NA","MIR3142 host gene [Source:HGNC Symbol;Acc:HGNC:51944]",{"v":0.007262,"d":"0.01"},{"v":0.232405,"d":"0.23"},{"v":0.0312471762655709,"d":"0.03"},{"v":-5.00013036709509,"d":"-5.00"},1,1,"down","no"]
["ENSG00000232995","RGS5","ENST00000451759;ENST00000439699;ENST00000528818;ENST00000429865;ENST00000449680","NA","NA","NA","NA","regulator of G protein signaling 5 [Source:NCBI gene;Acc:8490]",{"v":0.139473357694429,"d":"0.14"},{"v":0.0240736687810259,"d":"0.02"},{"v":5.79360624103782,"d":"5.79"},{"v":2.5344616360398,"d":"2.53"},1,1,"up","no"]
["ENSG00000164764","SBSPON","ENST00000297354","GO:0005576(extracellular region);GO:0006955(immune response);GO:0005044(scavenger receptor activity);GO:0006898(receptor-mediated endocytosis);GO:0005578(proteinaceous extracellular matrix);GO:0030247(polysaccharide binding);GO:0031012(extracellular matrix)","NA","NA","NA","somatomedin B and thrombospondin type 1 domain containing [Source:HGNC Symbol;Acc:HGNC:30362]",{"v":0.0605974620123203,"d":"0.06"},{"v":0.0716995386721424,"d":"0.07"},{"v":0.845158325068337,"d":"0.85"},{"v":-0.242706465451216,"d":"-0.24"},1,1,"down","no"]
["ENSG00000105695","MAG","ENST00000361922;ENST00000392213","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0030246(carbohydrate binding);GO:0007155(cell adhesion);GO:0005886(plasma membrane);GO:0045121(membrane raft);GO:0050900(leukocyte migration);GO:0008289(lipid binding);GO:0005887(integral component of plasma membrane);GO:0043524(negative regulation of neuron apoptotic process);GO:0033691(sialic acid binding);GO:0010977(negative regulation of neuron projection development);GO:0043209(myelin sheath);GO:0050771(negative regulation of axonogenesis);GO:0098742(cell-cell adhesion via plasma-membrane adhesion molecules);GO:0005102(receptor binding);GO:0019901(protein kinase binding);GO:0042803(protein homodimerization activity);GO:1905576(ganglioside GT1b binding);GO:0007399(nervous system development);GO:0022010(central nervous system myelination);GO:0030517(negative regulation of axon extension);GO:0031643(positive regulation of myelination);GO:0045665(negative regulation of neuron differentiation);GO:0048711(positive regulation of astrocyte differentiation);GO:0071260(cellular response to mechanical stimulus);GO:0005737(cytoplasm);GO:0033270(paranode region of axon);GO:0035749(myelin sheath adaxonal region);GO:0043218(compact myelin);GO:0043220(Schmidt-Lanterman incisure);GO:0097453(mesaxon);GO:0097453(mesaxon)","04514(Cell adhesion molecules (CAMs));04514(Cell adhesion molecules (CAMs))","K06771","NA","myelin associated glycoprotein [Source:HGNC Symbol;Acc:HGNC:6783]",0,0,1,0,1,1,"no","no"]
["ENSG00000157765","SLC34A2","ENST00000382051","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005886(plasma membrane);GO:0015321(sodium-dependent phosphate transmembrane transporter activity);GO:0044341(sodium-dependent phosphate transport);GO:0006810(transport);GO:0015293(symporter activity);GO:0055085(transmembrane transport);GO:0006811(ion transport);GO:0006814(sodium ion transport);GO:0035725(sodium ion transmembrane transport);GO:0005737(cytoplasm);GO:0005887(integral component of plasma membrane);GO:0044267(cellular protein metabolic process);GO:0006817(phosphate ion transport);GO:0035435(phosphate ion transmembrane transport);GO:0016324(apical plasma membrane);GO:0031982(vesicle);GO:0005436(sodium:phosphate symporter activity);GO:0031526(brush border membrane);GO:0031402(sodium ion binding);GO:0043627(response to estrogen);GO:0030643(cellular phosphate ion homeostasis);GO:0042301(phosphate ion binding);GO:0005903(brush border);GO:0001701(in utero embryonic development)","04978(Mineral absorption)","K14683","NA","solute carrier family 34 member 2 [Source:HGNC Symbol;Acc:HGNC:11020]",0,0,1,0,1,1,"no","no"]
["ENSG00000228719","AL022313.2","ENST00000442579","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000280799","DUX4L5","ENST00000630834","NA","NA","NA","NA","double homeobox 4 like 5 [Source:HGNC Symbol;Acc:HGNC:38689]",0,0,1,0,1,1,"no","no"]
["ENSG00000164123","C4orf45","ENST00000508011;ENST00000434826","NA","NA","NA","NA","chromosome 4 open reading frame 45 [Source:HGNC Symbol;Acc:HGNC:26342]",0,{"v":0.0157030347705146,"d":"0.02"},"-inf","-inf",1,1,"down","no"]
["ENSG00000214548","MEG3","ENST00000452120;ENST00000455531;ENST00000523671;ENST00000398461","NA","NA","NA","NA","maternally expressed 3 (non-protein coding) [Source:HGNC Symbol;Acc:HGNC:14575]",{"v":0.0134743144777728,"d":"0.01"},0,"inf","inf",1,1,"up","no"]
["MSTRG.14605","AC105202.1","ENST00000518831;ENST00000517833;ENST00000518024;ENST00000502167","NA","NA","NA","NA",null,{"v":0.0380821853101479,"d":"0.04"},{"v":0.0288659286270439,"d":"0.03"},{"v":1.31927802504401,"d":"1.32"},{"v":0.399748630612763,"d":"0.40"},1,1,"up","no"]
["ENSG00000246596","AC139795.1","ENST00000500444;ENST00000515045;ENST00000499314","NA","NA","NA","NA",null,{"v":0.503451097575399,"d":"0.50"},{"v":0.219251482554701,"d":"0.22"},{"v":2.29622665128293,"d":"2.30"},{"v":1.19926505165798,"d":"1.20"},1,1,"up","no"]
["ENSG00000138347","MYPN","ENST00000613327","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0003779(actin binding);GO:0005515(protein binding);GO:0051015(actin filament binding);GO:0030018(Z disc);GO:0045214(sarcomere organization);GO:0030017(sarcomere);GO:0031674(I band);GO:0017124(SH3 domain binding);GO:0008092(cytoskeletal protein binding);GO:0030334(regulation of cell migration);GO:0048739(cardiac muscle fiber development);GO:0051371(muscle alpha-actinin binding);GO:0051493(regulation of cytoskeleton organization)","NA","NA","NA","myopalladin [Source:HGNC Symbol;Acc:HGNC:23246]",0,0,1,0,1,1,"no","no"]
["ENSG00000070729","CNGB1","ENST00000251102;ENST00000311183","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0000166(nucleotide binding);GO:0007601(visual perception);GO:0006811(ion transport);GO:0005515(protein binding);GO:0071805(potassium ion transmembrane transport);GO:0030552(cAMP binding);GO:0005221(intracellular cyclic nucleotide activated cation channel activity);GO:0098655(cation transmembrane transport);GO:0007608(sensory perception of smell);GO:0050896(response to stimulus);GO:0005886(plasma membrane);GO:0005887(integral component of plasma membrane);GO:0030553(cGMP binding);GO:0001895(retina homeostasis);GO:0005249(voltage-gated potassium channel activity);GO:0050908(detection of light stimulus involved in visual perception);GO:0000139(Golgi membrane);GO:0022400(regulation of rhodopsin mediated signaling pathway);GO:0042391(regulation of membrane potential);GO:0016056(rhodopsin mediated signaling pathway);GO:0030660(Golgi-associated vesicle membrane);GO:0060170(ciliary membrane);GO:0006812(cation transport);GO:0005223(intracellular cGMP activated cation channel activity);GO:0005222(intracellular cAMP activated cation channel activity);GO:0015276(ligand-gated ion channel activity);GO:0043855(cyclic nucleotide-gated ion channel activity);GO:0007602(phototransduction);GO:0033365(protein localization to organelle);GO:0035845(photoreceptor cell outer segment organization);GO:0045494(photoreceptor cell maintenance);GO:0051290(protein heterotetramerization);GO:0051480(regulation of cytosolic calcium ion concentration);GO:0001750(photoreceptor outer segment);GO:0017071(intracellular cyclic nucleotide activated cation channel complex);GO:0043195(terminal bouton);GO:1902495(transmembrane transporter complex);GO:1902495(transmembrane transporter complex)","04024(cAMP signaling pathway);04022(cGMP - PKG signaling pathway);04744(Phototransduction);04740(Olfactory transduction);04740(Olfactory transduction)","K04952","NA","cyclic nucleotide gated channel beta 1 [Source:HGNC Symbol;Acc:HGNC:2151]",0,{"v":0.00214725924910935,"d":"0.00"},"-inf","-inf",1,1,"down","no"]
["ENSG00000181984","GOLGA8CP","ENST00000446144","NA","NA","NA","NA","golgin A8 family member C, pseudogene [Source:HGNC Symbol;Acc:HGNC:32375]",0,0,1,0,1,1,"no","no"]
["MSTRG.2018","AL391425.1","ENST00000618591","NA","NA","NA","NA",null,0,{"v":0.048445203236554,"d":"0.05"},"-inf","-inf",1,1,"down","no"]
["ENSG00000226435","ANKRD18DP","ENST00000440713;ENST00000435620","NA","NA","NA","NA","ankyrin repeat domain 18D, pseudogene [Source:HGNC Symbol;Acc:HGNC:28016]",{"v":0.0154013893882285,"d":"0.02"},{"v":0.00469035169614381,"d":"0.00"},{"v":3.28363209967619,"d":"3.28"},{"v":1.71529249565854,"d":"1.72"},1,1,"up","no"]
["ENSG00000127533","F2RL3","ENST00000248076","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0004930(G-protein coupled receptor activity);GO:0007186(G-protein coupled receptor signaling pathway);GO:0005886(plasma membrane);GO:0004871(signal transducer activity);GO:0007165(signal transduction);GO:0007596(blood coagulation);GO:0015057(thrombin-activated receptor activity);GO:0070493(thrombin-activated receptor signaling pathway);GO:0005576(extracellular region);GO:0005887(integral component of plasma membrane);GO:0007599(hemostasis);GO:0009611(response to wounding);GO:0030168(platelet activation);GO:0035025(positive regulation of Rho protein signal transduction);GO:0051482(positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway);GO:0051281(positive regulation of release of sequestered calcium ion into cytosol);GO:0060155(platelet dense granule organization);GO:0007200(phospholipase C-activating G-protein coupled receptor signaling pathway)","04015(Rap1 signaling pathway);04080(Neuroactive ligand-receptor interaction);04610(Complement and coagulation cascades);04611(Platelet activation);05200(Pathways in cancer)","K04236","NA","F2R like thrombin or trypsin receptor 3 [Source:HGNC Symbol;Acc:HGNC:3540]",{"v":0.011503,"d":"0.01"},{"v":1.94E-4,"d":"0.00"},{"v":59.2938144329897,"d":"59.29"},{"v":5.88980970467875,"d":"5.89"},1,1,"up","no"]
["ENSG00000235033","AL590999.1","ENST00000437947;ENST00000607215;ENST00000430595","NA","NA","NA","NA",null,0,{"v":0.00472114414940181,"d":"0.00"},"-inf","-inf",1,1,"down","no"]
["MSTRG.9744","RN7SL116P","ENST00000470786","NA","NA","NA","NA","RNA, 7SL, cytoplasmic 116, pseudogene [Source:HGNC Symbol;Acc:HGNC:46132]",0,0,1,0,1,1,"no","no"]
["MSTRG.6974","AC018521.5","ENST00000580459;ENST00000582787;ENST00000577279","NA","NA","NA","NA",null,{"v":0.147699088427438,"d":"0.15"},{"v":0.156065342043864,"d":"0.16"},{"v":0.946392623071466,"d":"0.95"},{"v":-0.0794892666658015,"d":"-0.08"},1,1,"down","no"]
["ENSG00000214391","TUBAP2","ENST00000530835","NA","NA","NA","NA","tubulin alpha pseudogene 2 [Source:HGNC Symbol;Acc:HGNC:14531]",{"v":0.016466,"d":"0.02"},{"v":0.087549,"d":"0.09"},{"v":0.188077533723972,"d":"0.19"},{"v":-2.41060056883741,"d":"-2.41"},1,1,"down","no"]
["ENSG00000216613","AL023284.2","ENST00000405850","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["MSTRG.12731","AL353759.1","ENST00000635439","NA","NA","NA","NA",null,{"v":0.599371,"d":"0.60"},{"v":0.388249,"d":"0.39"},{"v":1.54377989383102,"d":"1.54"},{"v":0.626467073386676,"d":"0.63"},1,1,"up","no"]
["MSTRG.3188","TAS2R15P","ENST00000390674","NA","NA","NA","NA","taste 2 receptor member 15 pseudogene [Source:HGNC Symbol;Acc:HGNC:19106]",0,0,1,0,1,1,"no","no"]
["MSTRG.8095","AC010632.2","ENST00000588369","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["MSTRG.12348","AC113382.1","ENST00000500267","NA","NA","NA","NA",null,{"v":0.042113,"d":"0.04"},0,"inf","inf",1,1,"up","no"]
["ENSG00000176294","OR4N2","ENST00000315947","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0004930(G-protein coupled receptor activity);GO:0007186(G-protein coupled receptor signaling pathway);GO:0005886(plasma membrane);GO:0004871(signal transducer activity);GO:0007165(signal transduction);GO:0004984(olfactory receptor activity);GO:0007608(sensory perception of smell);GO:0050896(response to stimulus);GO:0050911(detection of chemical stimulus involved in sensory perception of smell);GO:0004888(transmembrane signaling receptor activity);GO:0050907(detection of chemical stimulus involved in sensory perception)","04740(Olfactory transduction)","NA","NA","olfactory receptor family 4 subfamily N member 2 [Source:HGNC Symbol;Acc:HGNC:14742]",0,0,1,0,1,1,"no","no"]
["ENSG00000039600","SOX30","ENST00000265007","GO:0005634(nucleus);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0043565(sequence-specific DNA binding);GO:0031960(response to corticosteroid);GO:0007283(spermatogenesis)","NA","NA","NA","SRY-box 30 [Source:HGNC Symbol;Acc:HGNC:30635]",{"v":0.087996970613656,"d":"0.09"},{"v":0.0806410789397868,"d":"0.08"},{"v":1.09121767429925,"d":"1.09"},{"v":0.125938916792696,"d":"0.13"},1,1,"up","no"]
["ENSG00000237001","WASF3-AS1","ENST00000626038","NA","NA","NA","NA","WASF3 antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:39841]",{"v":0.00746392565789474,"d":"0.01"},{"v":0.00837035460526316,"d":"0.01"},{"v":0.891709612063691,"d":"0.89"},{"v":-0.165354126269792,"d":"-0.17"},1,1,"down","no"]
["ENSG00000237438","CECR7","ENST00000441006;ENST00000609932;ENST00000609596;ENST00000414401","NA","NA","NA","NA","cat eye syndrome chromosome region, candidate 7 (non-protein coding) [Source:HGNC Symbol;Acc:HGNC:1845]",{"v":0.142751436110487,"d":"0.14"},{"v":0.102706472939591,"d":"0.10"},{"v":1.38989717030249,"d":"1.39"},{"v":0.474978151019053,"d":"0.47"},1,1,"up","no"]
["ENSG00000068781","STON1-GTF2A1L","ENST00000394754;ENST00000405008;ENST00000402114","GO:0006897(endocytosis);GO:1903506(regulation of nucleic acid-templated transcription);GO:0006367(transcription initiation from RNA polymerase II promoter);GO:0005672(transcription factor TFIIA complex);GO:0030100(regulation of endocytosis);GO:0003713(transcription coactivator activity);GO:0006366(transcription from RNA polymerase II promoter);GO:0006366(transcription from RNA polymerase II promoter)","NA","NA","NA","STON1-GTF2A1L readthrough [Source:HGNC Symbol;Acc:HGNC:30651]",{"v":0.0123705598509548,"d":"0.01"},{"v":0.0856316888681882,"d":"0.09"},{"v":0.144462406551349,"d":"0.14"},{"v":-2.79123398581697,"d":"-2.79"},1,1,"down","no"]
["ENSG00000251209","LINC00923","ENST00000503768","NA","NA","NA","NA","long intergenic non-protein coding RNA 923 [Source:HGNC Symbol;Acc:HGNC:28088]",0,0,1,0,1,1,"no","no"]
["ENSG00000185668","POU3F1","ENST00000373012","GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0043565(sequence-specific DNA binding);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0045893(positive regulation of transcription, DNA-templated);GO:0007420(brain development);GO:0010628(positive regulation of gene expression);GO:0008366(axon ensheathment);GO:0001105(RNA polymerase II transcription coactivator activity);GO:0008544(epidermis development);GO:0014044(Schwann cell development);GO:0022011(myelination in peripheral nervous system);GO:0030216(keratinocyte differentiation);GO:0030900(forebrain development);GO:0042552(myelination);GO:0005667(transcription factor complex)","NA","NA","NA","POU class 3 homeobox 1 [Source:HGNC Symbol;Acc:HGNC:9214]",0,0,1,0,1,1,"no","no"]
["ENSG00000218305","CDC14C","ENST00000428251","NA","NA","NA","NA","cell division cycle 14C, pseudogene [Source:HGNC Symbol;Acc:HGNC:22427]",0,0,1,0,1,1,"no","no"]
["ENSG00000229242","AL358452.1","ENST00000414995","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000236869","AC099669.1","ENST00000457331","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000237666","AC097527.1","ENST00000437031","NA","NA","NA","NA",null,{"v":0.058189,"d":"0.06"},0,"inf","inf",1,1,"up","no"]
["ENSG00000214711","CAPN14","ENST00000398824","GO:0005622(intracellular);GO:0006508(proteolysis);GO:0004198(calcium-dependent cysteine-type endopeptidase activity);GO:0046872(metal ion binding);GO:0016787(hydrolase activity);GO:0005509(calcium ion binding);GO:0008233(peptidase activity);GO:0008234(cysteine-type peptidase activity);GO:0005737(cytoplasm)","NA","NA","NA","calpain 14 [Source:HGNC Symbol;Acc:HGNC:16664]",{"v":0.0644327765321375,"d":"0.06"},{"v":0.131241154957648,"d":"0.13"},{"v":0.490949478103345,"d":"0.49"},{"v":-1.02635352541856,"d":"-1.03"},1,1,"down","no"]
["ENSG00000150636","CCDC102B","ENST00000577772;ENST00000582077;ENST00000360242;ENST00000580292;ENST00000578970;ENST00000577800;ENST00000584775","GO:0005515(protein binding);GO:0005515(protein binding)","NA","NA","NA","coiled-coil domain containing 102B [Source:HGNC Symbol;Acc:HGNC:26295]",{"v":0.114860789147287,"d":"0.11"},{"v":0.183705605684755,"d":"0.18"},{"v":0.625243790025613,"d":"0.63"},{"v":-0.677509271379547,"d":"-0.68"},1,1,"down","no"]
["ENSG00000224789","AC012363.1","ENST00000455707","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000226191","CLK3P2","ENST00000427566","NA","NA","NA","NA","CDC like kinase 3 pseudogene 2 [Source:HGNC Symbol;Acc:HGNC:49786]",0,{"v":0.017513,"d":"0.02"},"-inf","-inf",1,1,"down","no"]
["ENSG00000278668","AC005899.7","ENST00000618199","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000256379","TRAV8-5","ENST00000537369","NA","NA","NA","NA","T-cell receptor alpha variable 8-5 (pseudogene) [Source:HGNC Symbol;Acc:HGNC:12150]",{"v":0.385668,"d":"0.39"},{"v":0.131574,"d":"0.13"},{"v":2.93118701263168,"d":"2.93"},{"v":1.55148501633496,"d":"1.55"},1,1,"up","no"]
["ENSG00000278637","HIST1H4A","ENST00000617569","GO:0005634(nucleus);GO:0003723(RNA binding);GO:0016020(membrane);GO:0003677(DNA binding);GO:0046982(protein heterodimerization activity);GO:0006334(nucleosome assembly);GO:0000786(nucleosome);GO:0005694(chromosome);GO:0005515(protein binding);GO:0006352(DNA-templated transcription, initiation);GO:0005576(extracellular region);GO:0005654(nucleoplasm);GO:0070062(extracellular exosome);GO:0044267(cellular protein metabolic process);GO:1902036(regulation of hematopoietic stem cell differentiation);GO:0043234(protein complex);GO:0000784(nuclear chromosome, telomeric region);GO:0034080(CENP-A containing nucleosome assembly);GO:0031012(extracellular matrix);GO:0045815(positive regulation of gene expression, epigenetic);GO:0019904(protein domain specific binding);GO:0042393(histone binding);GO:1904837(beta-catenin-TCF complex assembly);GO:0045652(regulation of megakaryocyte differentiation);GO:0006335(DNA replication-dependent nucleosome assembly);GO:0006336(DNA replication-independent nucleosome assembly);GO:0000228(nuclear chromosome);GO:0060964(regulation of gene silencing by miRNA);GO:0000183(chromatin silencing at rDNA);GO:0045814(negative regulation of gene expression, epigenetic);GO:0006303(double-strand break repair via nonhomologous end joining);GO:0051290(protein heterotetramerization);GO:0045653(negative regulation of megakaryocyte differentiation);GO:0016233(telomere capping);GO:0032200(telomere organization);GO:0000788(nuclear nucleosome)","05203(Viral carcinogenesis);05322(Systemic lupus erythematosus);05034(Alcoholism)","K11254","NA","histone cluster 1 H4 family member a [Source:HGNC Symbol;Acc:HGNC:4781]",0,0,1,0,1,1,"no","no"]
["ENSG00000260012","AC007494.1","ENST00000562293","NA","NA","NA","NA",null,0,{"v":0.066963,"d":"0.07"},"-inf","-inf",1,1,"down","no"]
["ENSG00000274270","AL137060.1","ENST00000618151","NA","NA","NA","NA",null,{"v":0.100302,"d":"0.10"},{"v":0.134533,"d":"0.13"},{"v":0.745556852222131,"d":"0.75"},{"v":-0.423609725890877,"d":"-0.42"},1,1,"down","no"]
["ENSG00000255135","AP002360.2","ENST00000572035;ENST00000530759","NA","NA","NA","NA",null,{"v":0.271982704244032,"d":"0.27"},{"v":0.531473327586207,"d":"0.53"},{"v":0.511752312160793,"d":"0.51"},{"v":-0.966482379347765,"d":"-0.97"},1,1,"down","no"]
["ENSG00000255959","AP000777.2","ENST00000539897","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["MSTRG.2865","APOA1","ENST00000236850","GO:0005615(extracellular space);GO:0050728(negative regulation of inflammatory response);GO:0034115(negative regulation of heterotypic cell-cell adhesion);GO:0060354(negative regulation of cell adhesion molecule production);GO:0042632(cholesterol homeostasis);GO:0050713(negative regulation of interleukin-1 beta secretion);GO:0006810(transport);GO:0005576(extracellular region);GO:0006629(lipid metabolic process);GO:0008202(steroid metabolic process);GO:0042157(lipoprotein metabolic process);GO:0006869(lipid transport);GO:0005515(protein binding);GO:0008289(lipid binding);GO:0007229(integrin-mediated signaling pathway);GO:0008203(cholesterol metabolic process);GO:0006898(receptor-mediated endocytosis);GO:0005886(plasma membrane);GO:0042802(identical protein binding);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0044267(cellular protein metabolic process);GO:0072562(blood microparticle);GO:0043687(post-translational protein modification);GO:0055085(transmembrane transport);GO:0034364(high-density lipoprotein particle);GO:0002576(platelet degranulation);GO:0034774(secretory granule lumen);GO:0005788(endoplasmic reticulum lumen);GO:0031410(cytoplasmic vesicle);GO:0001523(retinoid metabolic process);GO:1903561(extracellular vesicle);GO:0050821(protein stabilization);GO:0019899(enzyme binding);GO:0051496(positive regulation of stress fiber assembly);GO:0034361(very-low-density lipoprotein particle);GO:0033344(cholesterol efflux);GO:0019216(regulation of lipid metabolic process);GO:0060761(negative regulation of response to cytokine stimulus);GO:0034384(high-density lipoprotein particle clearance);GO:0050919(negative chemotaxis);GO:0015485(cholesterol binding);GO:0005543(phospholipid binding);GO:0034375(high-density lipoprotein particle remodeling);GO:0034380(high-density lipoprotein particle assembly);GO:0043691(reverse cholesterol transport);GO:0034366(spherical high-density lipoprotein particle);GO:0017127(cholesterol transporter activity);GO:0007186(G-protein coupled receptor signaling pathway);GO:0032489(regulation of Cdc42 protein signal transduction);GO:0033700(phospholipid efflux);GO:0055091(phospholipid homeostasis);GO:0030139(endocytic vesicle);GO:0071682(endocytic vesicle lumen);GO:0010873(positive regulation of cholesterol esterification);GO:0001540(amyloid-beta binding);GO:0070508(cholesterol import);GO:0002740(negative regulation of cytokine secretion involved in immune response);GO:0005769(early endosome);GO:0035025(positive regulation of Rho protein signal transduction);GO:0031072(heat shock protein binding);GO:0031210(phosphatidylcholine binding);GO:0034190(apolipoprotein receptor binding);GO:0034191(apolipoprotein A-I receptor binding);GO:0045499(chemorepellent activity);GO:0060228(phosphatidylcholine-sterol O-acyltransferase activator activity);GO:0070653(high-density lipoprotein particle receptor binding);GO:0006656(phosphatidylcholine biosynthetic process);GO:0006695(cholesterol biosynthetic process);GO:0010804(negative regulation of tumor necrosis factor-mediated signaling pathway);GO:0010898(positive regulation of triglyceride catabolic process);GO:0010903(negative regulation of very-low-density lipoprotein particle remodeling);GO:0018158(protein oxidation);GO:0018206(peptidyl-methionine modification);GO:0019433(triglyceride catabolic process);GO:0030300(regulation of intestinal cholesterol absorption);GO:0030301(cholesterol transport);GO:0031102(neuron projection regeneration);GO:0034371(chylomicron remodeling);GO:0034378(chylomicron assembly);GO:0045723(positive regulation of fatty acid biosynthetic process);GO:0051006(positive regulation of lipoprotein lipase activity);GO:0051180(vitamin transport);GO:0051345(positive regulation of hydrolase activity);GO:0070328(triglyceride homeostasis);GO:1900026(positive regulation of substrate adhesion-dependent cell spreading);GO:0042627(chylomicron);GO:0005319(lipid transporter activity);GO:0005548(phospholipid transporter activity);GO:0008035(high-density lipoprotein particle binding);GO:0055102(lipase inhibitor activity);GO:0071813(lipoprotein particle binding);GO:0001932(regulation of protein phosphorylation);GO:0001935(endothelial cell proliferation);GO:0006644(phospholipid metabolic process);GO:0007584(response to nutrient);GO:0008211(glucocorticoid metabolic process);GO:0014012(peripheral nervous system axon regeneration);GO:0015914(phospholipid transport);GO:0019915(lipid storage);GO:0030325(adrenal gland development);GO:0031100(animal organ regeneration);GO:0042158(lipoprotein biosynthetic process);GO:0042493(response to drug);GO:0043534(blood vessel endothelial cell migration);GO:0043627(response to estrogen);GO:0051346(negative regulation of hydrolase activity);GO:0060192(negative regulation of lipase activity);GO:0005634(nucleus);GO:0009986(cell surface);GO:0034362(low-density lipoprotein particle);GO:0034363(intermediate-density lipoprotein particle);GO:0034365(discoidal high-density lipoprotein particle)","03320(PPAR signaling pathway);04975(Fat digestion and absorption);04979(Cholesterol metabolism);04977(Vitamin digestion and absorption);05143(African trypanosomiasis)","K08757","NA","apolipoprotein A1 [Source:HGNC Symbol;Acc:HGNC:600]",0,0,1,0,1,1,"no","no"]
["ENSG00000128617","OPN1SW","ENST00000249389","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0004930(G-protein coupled receptor activity);GO:0007186(G-protein coupled receptor signaling pathway);GO:0007601(visual perception);GO:0004871(signal transducer activity);GO:0007165(signal transduction);GO:0050896(response to stimulus);GO:0009881(photoreceptor activity);GO:0007602(phototransduction);GO:0018298(protein-chromophore linkage);GO:0005887(integral component of plasma membrane);GO:0001750(photoreceptor outer segment);GO:0004872(receptor activity);GO:0001523(retinoid metabolic process);GO:0008020(G-protein coupled photoreceptor activity);GO:0009584(detection of visible light);GO:0097381(photoreceptor disc membrane)","NA","NA","NA","opsin 1, short wave sensitive [Source:HGNC Symbol;Acc:HGNC:1012]",{"v":0.116367,"d":"0.12"},{"v":0.014182,"d":"0.01"},{"v":8.20526018897194,"d":"8.21"},{"v":3.03654908235421,"d":"3.04"},1,1,"up","no"]
["ENSG00000276747","PADI6","ENST00000619609","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016787(hydrolase activity);GO:0005509(calcium ion binding);GO:0004668(protein-arginine deiminase activity);GO:0018101(protein citrullination);GO:0007010(cytoskeleton organization);GO:0007028(cytoplasm organization);GO:0034613(cellular protein localization);GO:0036414(histone citrullination);GO:0043143(regulation of translation by machinery localization);GO:0045111(intermediate filament cytoskeleton)","NA","NA","NA","peptidyl arginine deiminase 6 [Source:HGNC Symbol;Acc:HGNC:20449]",{"v":0.02217,"d":"0.02"},0,"inf","inf",1,1,"up","no"]
["ENSG00000251691","AC114786.3","ENST00000509304","NA","NA","NA","NA",null,0,{"v":0.064777,"d":"0.06"},"-inf","-inf",1,1,"down","no"]
["MSTRG.2972","AP001318.2","ENST00000533378","NA","NA","NA","NA",null,{"v":0.089414,"d":"0.09"},{"v":0.103439,"d":"0.10"},{"v":0.864412842351531,"d":"0.86"},{"v":-0.210207588794481,"d":"-0.21"},1,1,"down","no"]
["ENSG00000238178","AC078993.1","ENST00000435789","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000220908","LINC02531","ENST00000404689","NA","NA","NA","NA","long intergenic non-protein coding RNA 2531 [Source:HGNC Symbol;Acc:HGNC:53557]",0,{"v":0.081842,"d":"0.08"},"-inf","-inf",1,1,"down","no"]
["MSTRG.11324","AC074033.1","ENST00000418623","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000161609","CCDC155","ENST00000447857","GO:0005634(nucleus);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005694(chromosome);GO:0005515(protein binding);GO:0051321(meiotic cell cycle);GO:0000781(chromosome, telomeric region);GO:0005640(nuclear outer membrane);GO:0042802(identical protein binding);GO:0070840(dynein complex binding);GO:0000724(double-strand break repair via homologous recombination);GO:0007015(actin filament organization);GO:0007129(synapsis);GO:0007283(spermatogenesis);GO:0034397(telomere localization);GO:0048477(oogenesis);GO:0051225(spindle assembly);GO:0051653(spindle localization);GO:0090220(chromosome localization to nuclear envelope involved in homologous chromosome segregation);GO:0000800(lateral element);GO:0034993(LINC complex);GO:0090619(meiotic spindle pole)","NA","NA","NA","coiled-coil domain containing 155 [Source:HGNC Symbol;Acc:HGNC:26520]",0,0,1,0,1,1,"no","no"]
["ENSG00000277740","Metazoa_SRP","ENST00000614579","NA","NA","NA","NA","Metazoan signal recognition particle RNA [Source:RFAM;Acc:RF00017]",0,0,1,0,1,1,"no","no"]
["ENSG00000269226","TMSB15B","ENST00000598087;ENST00000620307","GO:0007015(actin filament organization);GO:0003785(actin monomer binding);GO:0003785(actin monomer binding)","NA","NA","NA","thymosin beta 15B [Source:NCBI gene;Acc:286527]",{"v":0.160291999019928,"d":"0.16"},{"v":0.177406753348579,"d":"0.18"},{"v":0.903528168992401,"d":"0.90"},{"v":-0.146358514680566,"d":"-0.15"},1,1,"down","no"]
["ENSG00000278989","AP001148.1","ENST00000624124","NA","NA","NA","NA",null,{"v":0.067554,"d":"0.07"},0,"inf","inf",1,1,"up","no"]
["ENSG00000158816","VWA5B1","ENST00000289815;ENST00000467486","GO:0005576(extracellular region);GO:0005576(extracellular region)","NA","NA","NA","von Willebrand factor A domain containing 5B1 [Source:HGNC Symbol;Acc:HGNC:26538]",0,0,1,0,1,1,"no","no"]
["MSTRG.10277","IGLV3-22","ENST00000390307","GO:0016020(membrane);GO:0005886(plasma membrane);GO:0005576(extracellular region);GO:0002376(immune system process);GO:0002377(immunoglobulin production);GO:0006955(immune response);GO:0005615(extracellular space);GO:0003823(antigen binding);GO:0002250(adaptive immune response)","NA","NA","NA","immunoglobulin lambda variable 3-22 (gene/pseudogene) [Source:HGNC Symbol;Acc:HGNC:5906]",0,{"v":0.494011,"d":"0.49"},"-inf","-inf",1,1,"down","no"]
["ENSG00000156076","WIF1","ENST00000286574","GO:0005515(protein binding);GO:0005576(extracellular region);GO:0007275(multicellular organism development);GO:0016055(Wnt signaling pathway);GO:0017147(Wnt-protein binding);GO:0007165(signal transduction);GO:0030178(negative regulation of Wnt signaling pathway);GO:0045600(positive regulation of fat cell differentiation)","04310(Wnt signaling pathway)","K01691","NA","WNT inhibitory factor 1 [Source:HGNC Symbol;Acc:HGNC:18081]",0,0,1,0,1,1,"no","no"]
["MSTRG.15460","RTL8C","ENST00000257013;ENST00000495563;ENST00000464369","GO:0005515(protein binding);GO:0005515(protein binding)","NA","NA","NA","retrotransposon Gag like 8C [Source:HGNC Symbol;Acc:HGNC:2569]",{"v":3.647591,"d":"3.65"},0,"inf","inf",1,1,"up","no"]
["ENSG00000258712","AC060814.2","ENST00000556905","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000165269","AQP7","ENST00000379507","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005215(transporter activity);GO:0005737(cytoplasm);GO:0005886(plasma membrane);GO:0005887(integral component of plasma membrane);GO:0005911(cell-cell junction);GO:0015250(water channel activity);GO:0015254(glycerol channel activity);GO:0006091(generation of precursor metabolites and energy);GO:0006833(water transport);GO:0007588(excretion);GO:0015793(glycerol transport)","04923(Regulation of lipolysis in adipocyte);03320(PPAR signaling pathway)","K08771","NA","aquaporin 7 [Source:HGNC Symbol;Acc:HGNC:640]",{"v":0.00740220331239292,"d":"0.01"},{"v":0.00968819398438987,"d":"0.01"},{"v":0.764043672568875,"d":"0.76"},{"v":-0.388272990137078,"d":"-0.39"},1,1,"down","no"]
["MSTRG.6173","AC092718.4","ENST00000566639","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000248884","AC010280.2","ENST00000507733","NA","NA","NA","NA",null,0,{"v":0.124126,"d":"0.12"},"-inf","-inf",1,1,"down","no"]
["ENSG00000257921","AC025165.3","ENST00000546504;ENST00000471530","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000260277","AC009019.1","ENST00000568603;ENST00000568410","NA","NA","NA","NA",null,{"v":0.116658249566724,"d":"0.12"},{"v":0.0675492764298094,"d":"0.07"},{"v":1.72700961035377,"d":"1.73"},{"v":0.788276111107221,"d":"0.79"},1,1,"up","no"]
["ENSG00000180251","SLC9A4","ENST00000295269","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0055085(transmembrane transport);GO:0006811(ion transport);GO:0005886(plasma membrane);GO:0015297(antiporter activity);GO:0015299(solute:proton antiporter activity);GO:0015385(sodium:proton antiporter activity);GO:0006812(cation transport);GO:0006814(sodium ion transport);GO:0006885(regulation of pH);GO:1902600(hydrogen ion transmembrane transport);GO:0016323(basolateral plasma membrane);GO:0016324(apical plasma membrane);GO:0051453(regulation of intracellular pH);GO:0015386(potassium:proton antiporter activity);GO:0071805(potassium ion transmembrane transport);GO:0098719(sodium ion import across plasma membrane);GO:0001696(gastric acid secretion);GO:0002064(epithelial cell development)","04971(Gastric acid secretion)","K13961","NA","solute carrier family 9 member A4 [Source:HGNC Symbol;Acc:HGNC:11077]",0,0,1,0,1,1,"no","no"]
["MSTRG.866","AC243547.2","ENST00000616257","NA","NA","NA","NA",null,{"v":0.103732,"d":"0.10"},0,"inf","inf",1,1,"up","no"]
["ENSG00000213088","ACKR1","ENST00000368122;ENST00000368121","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0004871(signal transducer activity);GO:0007165(signal transduction);GO:0004930(G-protein coupled receptor activity);GO:0007186(G-protein coupled receptor signaling pathway);GO:0006954(inflammatory response);GO:0005886(plasma membrane);GO:0070098(chemokine-mediated signaling pathway);GO:0006952(defense response);GO:0019956(chemokine binding);GO:0005768(endosome);GO:0005769(early endosome);GO:0055037(recycling endosome);GO:0004872(receptor activity);GO:0004888(transmembrane signaling receptor activity);GO:0019957(C-C chemokine binding);GO:0032642(regulation of chemokine production);GO:0032642(regulation of chemokine production)","05144(Malaria);05144(Malaria)","K06574","NA","atypical chemokine receptor 1 (Duffy blood group) [Source:HGNC Symbol;Acc:HGNC:4035]",{"v":0.222748338081671,"d":"0.22"},{"v":0.168995403608737,"d":"0.17"},{"v":1.31807335184917,"d":"1.32"},{"v":0.398430659727129,"d":"0.40"},1,1,"up","no"]
["MSTRG.7831","HNRNPA1P10","ENST00000444945","NA","NA","NA","NA","heterogeneous nuclear ribonucleoprotein A1 pseudogene 10 [Source:HGNC Symbol;Acc:HGNC:39128]",{"v":16.411736,"d":"16.41"},0,"inf","inf",1,1,"up","no"]
["ENSG00000089091","DZANK1","ENST00000460891;ENST00000357236;ENST00000609267;ENST00000377630;ENST00000608192","GO:0046872(metal ion binding);GO:0046872(metal ion binding)","NA","NA","NA","double zinc ribbon and ankyrin repeat domains 1 [Source:HGNC Symbol;Acc:HGNC:15858]",{"v":0.167256808581357,"d":"0.17"},{"v":0.0875036721559148,"d":"0.09"},{"v":1.91142616601664,"d":"1.91"},{"v":0.93464947326755,"d":"0.93"},1,1,"up","no"]
["ENSG00000164325","TMEM174","ENST00000296776","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005515(protein binding)","NA","NA","NA","transmembrane protein 174 [Source:HGNC Symbol;Acc:HGNC:28187]",0,0,1,0,1,1,"no","no"]
["ENSG00000282907","Z98883.1","ENST00000409439","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000283728","MIR7108","ENST00000614319","NA","NA","NA","NA","microRNA 7108 [Source:HGNC Symbol;Acc:HGNC:49998]",0,0,1,0,1,1,"no","no"]
["ENSG00000283342","AC241584.2","ENST00000637142","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000237529","AL137847.2","ENST00000458111","NA","NA","NA","NA",null,{"v":0.022696,"d":"0.02"},{"v":0.035494,"d":"0.04"},{"v":0.639432016678875,"d":"0.64"},{"v":-0.645137112502689,"d":"-0.65"},1,1,"down","no"]
["ENSG00000104313","EYA1","ENST00000340726","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0005654(nucleoplasm);GO:0016787(hydrolase activity);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0016569(covalent chromatin modification);GO:0004725(protein tyrosine phosphatase activity);GO:0007275(multicellular organism development);GO:0004721(phosphoprotein phosphatase activity);GO:0006281(DNA repair);GO:0006974(cellular response to DNA damage stimulus);GO:0016604(nuclear body);GO:0009887(animal organ morphogenesis);GO:0035335(peptidyl-tyrosine dephosphorylation);GO:0042471(ear morphogenesis);GO:0005515(protein binding);GO:0030154(cell differentiation);GO:0016925(protein sumoylation);GO:0016576(histone dephosphorylation);GO:2001240(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand);GO:0009653(anatomical structure morphogenesis);GO:0045739(positive regulation of DNA repair);GO:0007605(sensory perception of sound);GO:0006302(double-strand break repair);GO:0010212(response to ionizing radiation);GO:0003723(RNA binding);GO:0000132(establishment of mitotic spindle orientation);GO:0001656(metanephros development);GO:0001657(ureteric bud development);GO:0001658(branching involved in ureteric bud morphogenesis);GO:0003151(outflow tract morphogenesis);GO:0006470(protein dephosphorylation);GO:0007389(pattern specification process);GO:0007501(mesodermal cell fate specification);GO:0014706(striated muscle tissue development);GO:0034613(cellular protein localization);GO:0035088(establishment or maintenance of apical/basal cell polarity);GO:0035909(aorta morphogenesis);GO:0042472(inner ear morphogenesis);GO:0042473(outer ear morphogenesis);GO:0042474(middle ear morphogenesis);GO:0045165(cell fate commitment);GO:0045664(regulation of neuron differentiation);GO:0045747(positive regulation of Notch signaling pathway);GO:0045893(positive regulation of transcription, DNA-templated);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0048665(neuron fate specification);GO:0048704(embryonic skeletal system morphogenesis);GO:0048752(semicircular canal morphogenesis);GO:0048856(anatomical structure development);GO:0050679(positive regulation of epithelial cell proliferation);GO:0060037(pharyngeal system development);GO:0060487(lung epithelial cell differentiation);GO:0071599(otic vesicle development);GO:0071600(otic vesicle morphogenesis);GO:0072513(positive regulation of secondary heart field cardioblast proliferation);GO:0090103(cochlea morphogenesis);GO:0032993(protein-DNA complex);GO:0043234(protein complex)","05202(Transcriptional misregulation in cancers)","K15616","EC:3.1.3.48","EYA transcriptional coactivator and phosphatase 1 [Source:HGNC Symbol;Acc:HGNC:3519]",0,0,1,0,1,1,"no","no"]
["ENSG00000090530","P3H2","ENST00000482780;ENST00000319332;ENST00000463171","GO:0046872(metal ion binding);GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0005794(Golgi apparatus);GO:0005783(endoplasmic reticulum);GO:0005506(iron ion binding);GO:0016705(oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen);GO:0031418(L-ascorbic acid binding);GO:0051213(dioxygenase activity);GO:0005604(basement membrane);GO:0008285(negative regulation of cell proliferation);GO:0005788(endoplasmic reticulum lumen);GO:0032963(collagen metabolic process);GO:0019797(procollagen-proline 3-dioxygenase activity);GO:0019511(peptidyl-proline hydroxylation);GO:0019511(peptidyl-proline hydroxylation)","NA","NA","NA","prolyl 3-hydroxylase 2 [Source:HGNC Symbol;Acc:HGNC:19317]",{"v":0.00906955985727029,"d":"0.01"},{"v":0.0090795766280107,"d":"0.01"},{"v":0.998896779976557,"d":"1.00"},{"v":-1.59248865112101E-3,"d":"-0.00"},1,1,"down","no"]
["MSTRG.14212","AC124242.1","ENST00000499554","NA","NA","NA","NA",null,{"v":0.0289638429661941,"d":"0.03"},{"v":0.0301839105779716,"d":"0.03"},{"v":0.959578875353947,"d":"0.96"},{"v":-0.0595266971117463,"d":"-0.06"},1,1,"down","no"]
["ENSG00000270883","AC080078.3","ENST00000605407","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000259448","LINC02352","ENST00000559292;ENST00000557928","NA","NA","NA","NA","long intergenic non-protein coding RNA 2352 [Source:HGNC Symbol;Acc:HGNC:53274]",{"v":0.157549975802209,"d":"0.16"},{"v":0.370629110994214,"d":"0.37"},{"v":0.425087968345445,"d":"0.43"},{"v":-1.23416666925303,"d":"-1.23"},1,1,"down","no"]
["ENSG00000148082","SHC3","ENST00000375835","GO:0035556(intracellular signal transduction);GO:0007165(signal transduction);GO:0043547(positive regulation of GTPase activity);GO:0005515(protein binding);GO:0007417(central nervous system development);GO:0005886(plasma membrane);GO:0005575(cellular_component);GO:0005829(cytosol);GO:0000165(MAPK cascade);GO:0004871(signal transducer activity);GO:0007411(axon guidance);GO:0005088(Ras guanyl-nucleotide exchange factor activity);GO:0007169(transmembrane receptor protein tyrosine kinase signaling pathway);GO:0001784(phosphotyrosine residue binding);GO:0007173(epidermal growth factor receptor signaling pathway);GO:0007265(Ras protein signal transduction);GO:0030971(receptor tyrosine kinase binding);GO:0007611(learning or memory);GO:0035249(synaptic transmission, glutamatergic)","04014(Ras signaling pathway);04012(ErbB signaling pathway);04072(Phospholipase D signaling pathway);04510(Focal adhesion);04650(Natural killer cell mediated cytotoxicity);04062(Chemokine signaling pathway);04910(Insulin signaling pathway);04915(Estrogen signaling pathway);04917(Prolactin signaling pathway);04926(Relaxin signaling pathway);04722(Neurotrophin signaling pathway);05225(Hepatocellular carcinoma);05226(Gastric cancer);05214(Glioma);05220(Chronic myeloid leukemia);05224(Breast cancer);05034(Alcoholism);05100(Bacterial invasion of epithelial cells);01521(EGFR tyrosine kinase inhibitor resistance);01522(Endocrine resistance)","K17448","NA","SHC adaptor protein 3 [Source:HGNC Symbol;Acc:HGNC:18181]",{"v":0.00636016920132944,"d":"0.01"},{"v":0.000594206063047638,"d":"0.00"},{"v":10.703642384106,"d":"10.70"},{"v":3.42002991537254,"d":"3.42"},1,1,"up","no"]
["MSTRG.7909","AC022149.1","ENST00000596032","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["MSTRG.56","AL645728.1","ENST00000366221","NA","NA","NA","NA",null,{"v":0.304235,"d":"0.30"},0,"inf","inf",1,1,"up","no"]
["MSTRG.13441","AC073957.3","ENST00000609998","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000249092","AC008945.1","ENST00000505144","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000185681","MORN5","ENST00000373764","NA","NA","NA","NA","MORN repeat containing 5 [Source:HGNC Symbol;Acc:HGNC:17841]",0,0,1,0,1,1,"no","no"]
["ENSG00000176601","MAP3K19","ENST00000478805;ENST00000392915","GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0005737(cytoplasm);GO:0042981(regulation of apoptotic process);GO:0007346(regulation of mitotic cell cycle);GO:0031098(stress-activated protein kinase signaling cascade);GO:0023014(signal transduction by protein phosphorylation);GO:0032147(activation of protein kinase activity);GO:0032147(activation of protein kinase activity)","NA","NA","NA","mitogen-activated protein kinase kinase kinase 19 [Source:HGNC Symbol;Acc:HGNC:26249]",0,{"v":0.00934521488555903,"d":"0.01"},"-inf","-inf",1,1,"down","no"]
["ENSG00000224839","RPL12P17","ENST00000432393","NA","NA","NA","NA","ribosomal protein L12 pseudogene 17 [Source:HGNC Symbol;Acc:HGNC:36263]",{"v":0.052627,"d":"0.05"},0,"inf","inf",1,1,"up","no"]
["MSTRG.5886","PYCARD-AS1","ENST00000561916","NA","NA","NA","NA","PYCARD antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:45036]",{"v":1.928E-3,"d":"0.00"},{"v":0.968721,"d":"0.97"},{"v":0.0019902531275775,"d":"0.00"},{"v":-8.97283235506052,"d":"-8.97"},1,1,"down","no"]
["MSTRG.5700","MYH11","ENST00000573908;ENST00000576164;ENST00000570785;ENST00000571275;ENST00000452625","GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0003774(motor activity);GO:0051015(actin filament binding);GO:0016459(myosin complex);GO:0003779(actin binding);GO:0005515(protein binding);GO:0042470(melanosome);GO:0005516(calmodulin binding);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0032982(myosin filament);GO:0006936(muscle contraction);GO:0008307(structural constituent of muscle);GO:0006939(smooth muscle contraction);GO:0005859(muscle myosin complex);GO:0048251(elastic fiber assembly);GO:0030241(skeletal muscle myosin thick filament assembly);GO:0048739(cardiac muscle fiber development);GO:0048739(cardiac muscle fiber development)","04530(Tight junction);04270(Vascular smooth muscle contraction);04270(Vascular smooth muscle contraction)","K10352","NA","myosin heavy chain 11 [Source:HGNC Symbol;Acc:HGNC:7569]",{"v":0.148350002980626,"d":"0.15"},{"v":0.0357321072404372,"d":"0.04"},{"v":4.15172835966253,"d":"4.15"},{"v":2.05371205376613,"d":"2.05"},1,1,"up","no"]
["MSTRG.7035","AC006141.1","ENST00000581917","NA","NA","NA","NA",null,0,{"v":0.023297,"d":"0.02"},"-inf","-inf",1,1,"down","no"]
["ENSG00000158955","WNT9B","ENST00000393461","GO:0005102(receptor binding);GO:0005576(extracellular region);GO:0007275(multicellular organism development);GO:0016055(Wnt signaling pathway);GO:0005578(proteinaceous extracellular matrix);GO:0005615(extracellular space);GO:0005109(frizzled binding);GO:0030182(neuron differentiation);GO:0045165(cell fate commitment);GO:0071300(cellular response to retinoic acid);GO:0007267(cell-cell signaling);GO:0061303(cornea development in camera-type eye);GO:0039706(co-receptor binding);GO:0001658(branching involved in ureteric bud morphogenesis);GO:0001701(in utero embryonic development);GO:0001822(kidney development);GO:0001932(regulation of protein phosphorylation);GO:0003339(regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis);GO:0009267(cellular response to starvation);GO:0009786(regulation of asymmetric cell division);GO:0030539(male genitalia development);GO:0032526(response to retinoic acid);GO:0035150(regulation of tube size);GO:0043085(positive regulation of catalytic activity);GO:0048701(embryonic cranial skeleton morphogenesis);GO:0048754(branching morphogenesis of an epithelial tube);GO:0060021(palate development);GO:0060070(canonical Wnt signaling pathway);GO:0060071(Wnt signaling pathway, planar cell polarity pathway);GO:0060993(kidney morphogenesis);GO:0061038(uterus morphogenesis);GO:0072003(kidney rudiment formation);GO:0072038(mesenchymal stem cell maintenance involved in nephron morphogenesis);GO:0072044(collecting duct development);GO:0072046(establishment of planar polarity involved in nephron morphogenesis);GO:0072078(nephron tubule morphogenesis);GO:0072164(mesonephric tubule development);GO:0072170(metanephric tubule development);GO:0072174(metanephric tubule formation);GO:0072181(mesonephric duct formation);GO:1902455(negative regulation of stem cell population maintenance);GO:1904948(midbrain dopaminergic neuron differentiation);GO:1905438(non-canonical Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation)","04310(Wnt signaling pathway);04390(Hippo signaling pathway);04150(mTOR signaling pathway);04550(Signaling pathways regulating pluripotency of stem cells);04916(Melanogenesis);05200(Pathways in cancer);05205(Proteoglycans in cancer);05225(Hepatocellular carcinoma);05226(Gastric cancer);05217(Basal cell carcinoma);05224(Breast cancer);05166(HTLV-I infection);05165(Human papillomavirus infection)","K01064","NA","Wnt family member 9B [Source:HGNC Symbol;Acc:HGNC:12779]",0,0,1,0,1,1,"no","no"]
["ENSG00000229591","AC006017.1","ENST00000424630","NA","NA","NA","NA",null,{"v":0.065041,"d":"0.07"},{"v":0.148983,"d":"0.15"},{"v":0.436566588134217,"d":"0.44"},{"v":-1.1957263744936,"d":"-1.20"},1,1,"down","no"]
["ENSG00000167634","NLRP7","ENST00000587103;ENST00000340844;ENST00000590030;ENST00000588756;ENST00000328092","GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0005524(ATP binding)","04621(NOD-like receptor signaling pathway);04621(NOD-like receptor signaling pathway)","K20864","NA","NLR family pyrin domain containing 7 [Source:HGNC Symbol;Acc:HGNC:22947]",{"v":0.170727753193664,"d":"0.17"},{"v":0.0894349494123659,"d":"0.09"},{"v":1.90896013600314,"d":"1.91"},{"v":0.93278697587382,"d":"0.93"},1,1,"up","no"]
["ENSG00000265313","LINC01476","ENST00000577478","NA","NA","NA","NA","long intergenic non-protein coding RNA 1476 [Source:HGNC Symbol;Acc:HGNC:51117]",0,{"v":0.112740061983471,"d":"0.11"},"-inf","-inf",1,1,"down","no"]
["ENSG00000164418","GRIK2","ENST00000436862;ENST00000369138","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005216(ion channel activity);GO:0006811(ion transport);GO:0034220(ion transmembrane transport);GO:0005886(plasma membrane);GO:0035725(sodium ion transmembrane transport);GO:0071805(potassium ion transmembrane transport);GO:0030054(cell junction);GO:0045202(synapse);GO:0045211(postsynaptic membrane);GO:0004872(receptor activity);GO:0004970(ionotropic glutamate receptor activity);GO:0005234(extracellular-glutamate-gated ion channel activity);GO:0035235(ionotropic glutamate receptor signaling pathway);GO:0060079(excitatory postsynaptic potential);GO:0005887(integral component of plasma membrane);GO:0048172(regulation of short-term neuronal synaptic plasticity);GO:0007268(chemical synaptic transmission);GO:0007215(glutamate receptor signaling pathway);GO:0050806(positive regulation of synaptic transmission);GO:0015276(ligand-gated ion channel activity);GO:0015277(kainate selective glutamate receptor activity);GO:0008066(glutamate receptor activity);GO:0030165(PDZ domain binding);GO:0031624(ubiquitin conjugating enzyme binding);GO:0031625(ubiquitin protein ligase binding);GO:0042802(identical protein binding);GO:0042803(protein homodimerization activity);GO:0001662(behavioral fear response);GO:0006874(cellular calcium ion homeostasis);GO:0006886(intracellular protein transport);GO:0019228(neuronal action potential);GO:0035249(synaptic transmission, glutamatergic);GO:0042391(regulation of membrane potential);GO:0043113(receptor clustering);GO:0043524(negative regulation of neuron apoptotic process);GO:0043525(positive regulation of neuron apoptotic process);GO:0046328(regulation of JNK cascade);GO:0048169(regulation of long-term neuronal synaptic plasticity);GO:0050804(modulation of synaptic transmission);GO:0051402(neuron apoptotic process);GO:0051967(negative regulation of synaptic transmission, glutamatergic);GO:0060080(inhibitory postsynaptic potential);GO:0008328(ionotropic glutamate receptor complex);GO:0014069(postsynaptic density);GO:0030424(axon);GO:0030425(dendrite);GO:0032839(dendrite cytoplasm);GO:0032983(kainate selective glutamate receptor complex);GO:0042734(presynaptic membrane);GO:0043025(neuronal cell body);GO:0043195(terminal bouton);GO:0043204(perikaryon);GO:0098794(postsynapse);GO:0098794(postsynapse)","04080(Neuroactive ligand-receptor interaction);04724(Glutamatergic synapse);04724(Glutamatergic synapse)","K05202","NA","glutamate ionotropic receptor kainate type subunit 2 [Source:HGNC Symbol;Acc:HGNC:4580]",0,0,1,0,1,1,"no","no"]
["MSTRG.9360","AC007256.1","ENST00000392253","NA","NA","NA","NA",null,{"v":0.038423,"d":"0.04"},0,"inf","inf",1,1,"up","no"]
["ENSG00000280457","DUX4L2","ENST00000561772","NA","NA","NA","NA","double homeobox 4 like 2 [Source:HGNC Symbol;Acc:HGNC:37267]",0,0,1,0,1,1,"no","no"]
["ENSG00000178999","AURKB","ENST00000578753;ENST00000578549;ENST00000585124;ENST00000583124;ENST00000316199;ENST00000580390;ENST00000584561;ENST00000581511","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0005654(nucleoplasm);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0051301(cell division);GO:0005694(chromosome);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0007049(cell cycle);GO:0030496(midbody);GO:0005819(spindle);GO:0000775(chromosome, centromeric region);GO:0000278(mitotic cell cycle);GO:0032133(chromosome passenger complex);GO:0032467(positive regulation of cytokinesis);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0032466(negative regulation of cytokinesis);GO:0005829(cytosol);GO:0031145(anaphase-promoting complex-dependent catabolic process);GO:0005876(spindle microtubule);GO:0031577(spindle checkpoint);GO:0043988(histone H3-S28 phosphorylation);GO:0007062(sister chromatid cohesion);GO:1901796(regulation of signal transduction by p53 class mediator);GO:0046777(protein autophosphorylation);GO:0042787(protein ubiquitination involved in ubiquitin-dependent protein catabolic process);GO:0032091(negative regulation of protein binding);GO:0032212(positive regulation of telomere maintenance via telomerase);GO:0051973(positive regulation of telomerase activity);GO:1904355(positive regulation of telomere capping);GO:0008608(attachment of spindle microtubules to kinetochore);GO:0004712(protein serine/threonine/tyrosine kinase activity);GO:0035174(histone serine kinase activity);GO:0007051(spindle organization);GO:0051233(spindle midzone);GO:0016925(protein sumoylation);GO:0034501(protein localization to kinetochore);GO:0051983(regulation of chromosome segregation);GO:0051256(mitotic spindle midzone assembly);GO:0034644(cellular response to UV);GO:0016570(histone modification);GO:0002903(negative regulation of B cell apoptotic process);GO:0000780(condensed nuclear chromosome, centromeric region);GO:0009838(abscission);GO:0036089(cleavage furrow formation);GO:0000779(condensed chromosome, centromeric region);GO:0044878(mitotic cytokinesis checkpoint);GO:0000776(kinetochore);GO:0007568(aging);GO:0008283(cell proliferation);GO:0010369(chromocenter);GO:0031616(spindle pole centrosome);GO:1990023(mitotic spindle midzone);GO:1990023(mitotic spindle midzone)","NA","NA","NA","aurora kinase B [Source:HGNC Symbol;Acc:HGNC:11390]",{"v":0.114201087014726,"d":"0.11"},{"v":0.129598408299866,"d":"0.13"},{"v":0.881192049446213,"d":"0.88"},{"v":-0.18247161650343,"d":"-0.18"},1,1,"down","no"]
["ENSG00000092445","TYRO3","ENST00000263798;ENST00000560227;ENST00000560992","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0004713(protein tyrosine kinase activity);GO:0018108(peptidyl-tyrosine phosphorylation);GO:0005634(nucleus);GO:0007155(cell adhesion);GO:0005789(endoplasmic reticulum membrane);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0007165(signal transduction);GO:0004714(transmembrane receptor protein tyrosine kinase activity);GO:0023014(signal transduction by protein phosphorylation);GO:0007283(spermatogenesis);GO:0005887(integral component of plasma membrane);GO:0046718(viral entry into host cell);GO:0045824(negative regulation of innate immune response);GO:0050728(negative regulation of inflammatory response);GO:0016032(viral process);GO:0043524(negative regulation of neuron apoptotic process);GO:0070527(platelet aggregation);GO:0042698(ovulation cycle);GO:0014065(phosphatidylinositol 3-kinase signaling);GO:0046777(protein autophosphorylation);GO:0043277(apoptotic cell clearance);GO:0005635(nuclear envelope);GO:0001618(virus receptor activity);GO:0030168(platelet activation);GO:0043491(protein kinase B signaling);GO:0034446(substrate adhesion-dependent cell spreading);GO:0043548(phosphatidylinositol 3-kinase binding);GO:0034122(negative regulation of toll-like receptor signaling pathway);GO:0070050(neuron cellular homeostasis);GO:0004716(signal transducer, downstream of receptor, with protein tyrosine kinase activity);GO:0046982(protein heterodimerization activity);GO:0001779(natural killer cell differentiation);GO:0021885(forebrain cell migration);GO:0032940(secretion by cell);GO:0051250(negative regulation of lymphocyte activation);GO:0060068(vagina development);GO:0060068(vagina development)","NA","NA","NA","TYRO3 protein tyrosine kinase [Source:HGNC Symbol;Acc:HGNC:12446]",{"v":0.00969096217450891,"d":"0.01"},0,"inf","inf",1,1,"up","no"]
["ENSG00000136449","MYCBPAP","ENST00000452039;ENST00000323776;ENST00000488432","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005515(protein binding);GO:0007275(multicellular organism development);GO:0030154(cell differentiation);GO:0007283(spermatogenesis);GO:0007268(chemical synaptic transmission);GO:0007268(chemical synaptic transmission)","NA","NA","NA","MYCBP associated protein [Source:HGNC Symbol;Acc:HGNC:19677]",{"v":0.0407402108979279,"d":"0.04"},{"v":0.0111948250191865,"d":"0.01"},{"v":3.63920032944726,"d":"3.64"},{"v":1.86362147034561,"d":"1.86"},1,1,"up","no"]
["ENSG00000278561","PTPN20CP","ENST00000614090","NA","NA","NA","NA","protein tyrosine phosphatase, non-receptor type 20C, pseudogene [Source:HGNC Symbol;Acc:HGNC:23424]",0,{"v":0.055042,"d":"0.06"},"-inf","-inf",1,1,"down","no"]
["ENSG00000183154","AC138356.1","ENST00000330539","NA","NA","NA","NA",null,{"v":0.076395,"d":"0.08"},{"v":0.072948,"d":"0.07"},{"v":1.04725283763777,"d":"1.05"},{"v":0.0666097933382548,"d":"0.07"},1,1,"up","no"]
["ENSG00000131668","BARX1","ENST00000253968","GO:0005634(nucleus);GO:0006355(regulation of transcription, DNA-templated);GO:0006366(transcription from RNA polymerase II promoter);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0043565(sequence-specific DNA binding);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0000977(RNA polymerase II regulatory region sequence-specific DNA binding);GO:0001228(transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding);GO:0009888(tissue development);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0048513(animal organ development);GO:0007267(cell-cell signaling);GO:0009952(anterior/posterior pattern specification);GO:0030178(negative regulation of Wnt signaling pathway);GO:0030855(epithelial cell differentiation);GO:0048536(spleen development);GO:0048856(anatomical structure development);GO:0055123(digestive system development)","NA","NA","NA","BARX homeobox 1 [Source:HGNC Symbol;Acc:HGNC:955]",0,0,1,0,1,1,"no","no"]
["ENSG00000278927","FP236240.2","ENST00000623896","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000224155","AC073136.2","ENST00000417282","NA","NA","NA","NA",null,0,{"v":0.029972,"d":"0.03"},"-inf","-inf",1,1,"down","no"]
["ENSG00000183929","DUSP5P1","ENST00000441325","NA","NA","NA","NA","dual specificity phosphatase 5 pseudogene 1 [Source:HGNC Symbol;Acc:HGNC:32020]",0,0,1,0,1,1,"no","no"]
["ENSG00000271978","AL359643.2","ENST00000606227","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000248792","LINC00266-2P","ENST00000509776","NA","NA","NA","NA","long intergenic non-protein coding RNA 266-2, pseudogene [Source:HGNC Symbol;Acc:HGNC:38529]",0,0,1,0,1,1,"no","no"]
["ENSG00000260500","AC010336.2","ENST00000564226","NA","NA","NA","NA",null,{"v":0.10498,"d":"0.10"},0,"inf","inf",1,1,"up","no"]
["ENSG00000257831","AL136418.1","ENST00000551799","NA","NA","NA","NA",null,{"v":0.044117,"d":"0.04"},0,"inf","inf",1,1,"up","no"]
["ENSG00000186977","KRTAP19-5","ENST00000334151","GO:0005515(protein binding);GO:0005882(intermediate filament);GO:0005829(cytosol);GO:0031424(keratinization)","NA","NA","NA","keratin associated protein 19-5 [Source:HGNC Symbol;Acc:HGNC:18940]",0,0,1,0,1,1,"no","no"]
["ENSG00000158764","ITLN2","ENST00000368029;ENST00000490489","GO:0046872(metal ion binding);GO:0030246(carbohydrate binding);GO:0005576(extracellular region);GO:0005576(extracellular region)","NA","NA","NA","intelectin 2 [Source:HGNC Symbol;Acc:HGNC:20599]",0,{"v":0.0311073355745721,"d":"0.03"},"-inf","-inf",1,1,"down","no"]
["ENSG00000270012","AC232271.1","ENST00000602455","NA","NA","NA","NA",null,0,{"v":0.257522,"d":"0.26"},"-inf","-inf",1,1,"down","no"]
["MSTRG.8469","AC020915.3","ENST00000595301","NA","NA","NA","NA",null,{"v":0.272117,"d":"0.27"},{"v":0.092531,"d":"0.09"},{"v":2.94081983335315,"d":"2.94"},{"v":1.55621840153547,"d":"1.56"},1,1,"up","no"]
["ENSG00000275088","AC026469.1","ENST00000621095","NA","NA","NA","NA",null,{"v":0.024102,"d":"0.02"},0,"inf","inf",1,1,"up","no"]
["ENSG00000234498","RPL13AP20","ENST00000459725","NA","NA","NA","NA","ribosomal protein L13a pseudogene 20 [Source:HGNC Symbol;Acc:HGNC:35709]",0,{"v":0.73165,"d":"0.73"},"-inf","-inf",1,1,"down","no"]
["ENSG00000197506","SLC28A3","ENST00000495823;ENST00000376238","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005887(integral component of plasma membrane);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005886(plasma membrane);GO:0005337(nucleoside transmembrane transporter activity);GO:1901642(nucleoside transmembrane transport);GO:0005415(nucleoside:sodium symporter activity);GO:0015389(pyrimidine- and adenine-specific:sodium symporter activity);GO:0015855(pyrimidine nucleobase transport);GO:0072531(pyrimidine-containing compound transmembrane transport);GO:1904823(purine nucleobase transmembrane transport);GO:0015390(purine-specific nucleoside:sodium symporter activity);GO:0015860(purine nucleoside transmembrane transport);GO:0015864(pyrimidine nucleoside transport);GO:0015864(pyrimidine nucleoside transport)","NA","NA","NA","solute carrier family 28 member 3 [Source:HGNC Symbol;Acc:HGNC:16484]",{"v":0.0460413904799526,"d":"0.05"},{"v":0.0100519885443413,"d":"0.01"},{"v":4.58032659675794,"d":"4.58"},{"v":2.19545047227945,"d":"2.20"},1,1,"up","no"]
["ENSG00000184672","RALYL","ENST00000522647;ENST00000521268","GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0005654(nucleoplasm);GO:0005515(protein binding);GO:0005634(nucleus);GO:0042802(identical protein binding);GO:0042802(identical protein binding)","NA","NA","NA","RALY RNA binding protein like [Source:HGNC Symbol;Acc:HGNC:27036]",0,0,1,0,1,1,"no","no"]
["ENSG00000259198","AC020658.2","ENST00000559030","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000183831","ANKRD45","ENST00000333279","GO:0003674(molecular_function);GO:0008150(biological_process);GO:0005575(cellular_component);GO:0005515(protein binding)","NA","NA","NA","ankyrin repeat domain 45 [Source:HGNC Symbol;Acc:HGNC:24786]",0,0,1,0,1,1,"no","no"]
["ENSG00000277008","TEX28P2","ENST00000617764","NA","NA","NA","NA","testis expressed 28 pseudogene 2 [Source:HGNC Symbol;Acc:HGNC:33357]",0,{"v":0.012504,"d":"0.01"},"-inf","-inf",1,1,"down","no"]
["ENSG00000278214","LINC02139","ENST00000612023","NA","NA","NA","NA","long intergenic non-protein coding RNA 2139 [Source:HGNC Symbol;Acc:HGNC:52999]",{"v":0.012808,"d":"0.01"},0,"inf","inf",1,1,"up","no"]
["MSTRG.9817","CEBPB-AS1","ENST00000613921","NA","NA","NA","NA","CEBPB antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:51226]",{"v":0.091112,"d":"0.09"},{"v":0.028765,"d":"0.03"},{"v":3.16746045541457,"d":"3.17"},{"v":1.66332660795853,"d":"1.66"},1,1,"up","no"]
["ENSG00000150594","ADRA2A","ENST00000280155","GO:0005737(cytoplasm);GO:0030335(positive regulation of cell migration);GO:0032148(activation of protein kinase B activity);GO:0007194(negative regulation of adenylate cyclase activity);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0004930(G-protein coupled receptor activity);GO:0007186(G-protein coupled receptor signaling pathway);GO:0005886(plasma membrane);GO:0004871(signal transducer activity);GO:0007165(signal transduction);GO:0030168(platelet activation);GO:0019229(regulation of vasoconstriction);GO:0006940(regulation of smooth muscle contraction);GO:0005515(protein binding);GO:0004935(adrenergic receptor activity);GO:0004938(alpha2-adrenergic receptor activity);GO:0042803(protein homodimerization activity);GO:0046982(protein heterodimerization activity);GO:0007266(Rho protein signal transduction);GO:0046676(negative regulation of insulin secretion);GO:0006928(movement of cell or subcellular component);GO:0050796(regulation of insulin secretion);GO:1901020(negative regulation of calcium ion transmembrane transporter activity);GO:0032870(cellular response to hormone stimulus);GO:0019901(protein kinase binding);GO:0043235(receptor complex);GO:0043406(positive regulation of MAP kinase activity);GO:0007265(Ras protein signal transduction);GO:0030036(actin cytoskeleton organization);GO:0001819(positive regulation of cytokine production);GO:0032147(activation of protein kinase activity);GO:0051044(positive regulation of membrane protein ectodomain proteolysis);GO:0008284(positive regulation of cell proliferation);GO:0005887(integral component of plasma membrane);GO:0050995(negative regulation of lipid catabolic process);GO:0042593(glucose homeostasis);GO:0016323(basolateral plasma membrane);GO:0090303(positive regulation of wound healing);GO:0071880(adenylate cyclase-activating adrenergic receptor signaling pathway);GO:0031692(alpha-1B adrenergic receptor binding);GO:0031696(alpha-2C adrenergic receptor binding);GO:0031996(thioesterase binding);GO:0032795(heterotrimeric G-protein binding);GO:0051379(epinephrine binding);GO:0051380(norepinephrine binding);GO:0010700(negative regulation of norepinephrine secretion);GO:0030818(negative regulation of cAMP biosynthetic process);GO:0032811(negative regulation of epinephrine secretion);GO:0035625(epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathway);GO:0043268(positive regulation of potassium ion transport);GO:0045741(positive regulation of epidermal growth factor-activated receptor activity);GO:0045955(negative regulation of calcium ion-dependent exocytosis);GO:0050892(intestinal absorption);GO:0051926(negative regulation of calcium ion transport);GO:0061179(negative regulation of insulin secretion involved in cellular response to glucose stimulus);GO:0071878(negative regulation of adrenergic receptor signaling pathway);GO:0071881(adenylate cyclase-inhibiting adrenergic receptor signaling pathway);GO:0071882(phospholipase C-activating adrenergic receptor signaling pathway);GO:0071883(activation of MAPK activity by adrenergic receptor signaling pathway)","04022(cGMP - PKG signaling pathway);04080(Neuroactive ligand-receptor interaction)","K04138","NA","adrenoceptor alpha 2A [Source:HGNC Symbol;Acc:HGNC:281]",0,{"v":0.18935,"d":"0.19"},"-inf","-inf",1,1,"down","no"]
["ENSG00000284283","AC106774.7","ENST00000638408","GO:0005634(nucleus);GO:0046982(protein heterodimerization activity);GO:0006367(transcription initiation from RNA polymerase II promoter)","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000205790","DPP9-AS1","ENST00000381796","NA","NA","NA","NA","DPP9 antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:50706]",{"v":0.047301,"d":"0.05"},{"v":0.012541,"d":"0.01"},{"v":3.7717087951519,"d":"3.77"},{"v":1.91521829319009,"d":"1.92"},1,1,"up","no"]
["ENSG00000197859","ADAMTSL2","ENST00000393061","GO:0030512(negative regulation of transforming growth factor beta receptor signaling pathway);GO:0008270(zinc ion binding);GO:0005576(extracellular region);GO:0006508(proteolysis);GO:0004222(metalloendopeptidase activity);GO:0008233(peptidase activity);GO:0005515(protein binding);GO:0050436(microfibril binding);GO:0030198(extracellular matrix organization);GO:0060481(lobar bronchus epithelium development);GO:0005578(proteinaceous extracellular matrix)","NA","NA","NA","ADAMTS like 2 [Source:HGNC Symbol;Acc:HGNC:14631]",{"v":0.0113574513577079,"d":"0.01"},{"v":0.0108808766303186,"d":"0.01"},{"v":1.04379929518375,"d":"1.04"},{"v":0.0618443329043223,"d":"0.06"},1,1,"up","no"]
["ENSG00000273265","AC092636.1","ENST00000608609","NA","NA","NA","NA",null,{"v":0.32678,"d":"0.33"},{"v":0.5456,"d":"0.55"},{"v":0.598936950146628,"d":"0.60"},{"v":-0.739523955810484,"d":"-0.74"},1,1,"down","no"]
["ENSG00000049249","TNFRSF9","ENST00000474475;ENST00000377507;ENST00000615230","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0006915(apoptotic process);GO:0004872(receptor activity);GO:0008285(negative regulation of cell proliferation);GO:0006955(immune response);GO:0005886(plasma membrane);GO:0009897(external side of plasma membrane);GO:0006954(inflammatory response);GO:0097190(apoptotic signaling pathway);GO:0033209(tumor necrosis factor-mediated signaling pathway);GO:0005887(integral component of plasma membrane);GO:0005031(tumor necrosis factor-activated receptor activity);GO:0007275(multicellular organism development);GO:0032496(response to lipopolysaccharide);GO:0042127(regulation of cell proliferation);GO:0042981(regulation of apoptotic process);GO:0019955(cytokine binding);GO:0070207(protein homotrimerization);GO:2001180(negative regulation of interleukin-10 secretion);GO:2001183(negative regulation of interleukin-12 secretion);GO:0005615(extracellular space);GO:0005615(extracellular space)","04060(Cytokine-cytokine receptor interaction);04060(Cytokine-cytokine receptor interaction)","K05146","NA","TNF receptor superfamily member 9 [Source:HGNC Symbol;Acc:HGNC:11924]",{"v":0.694179511293635,"d":"0.69"},{"v":0.0956236125414626,"d":"0.10"},{"v":7.25949891291377,"d":"7.26"},{"v":2.85986996959796,"d":"2.86"},1,1,"up","no"]
["MSTRG.4526","PROX2","ENST00000619947;ENST00000556489;ENST00000556084","GO:0005634(nucleus);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0030182(neuron differentiation);GO:0001078(transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0001946(lymphangiogenesis);GO:0055007(cardiac muscle cell differentiation);GO:0060836(lymphatic endothelial cell differentiation);GO:0070309(lens fiber cell morphogenesis);GO:0070309(lens fiber cell morphogenesis)","NA","NA","NA","prospero homeobox 2 [Source:HGNC Symbol;Acc:HGNC:26715]",{"v":0.173989055847569,"d":"0.17"},{"v":0.0555812693823916,"d":"0.06"},{"v":3.13035412434624,"d":"3.13"},{"v":1.6463258726657,"d":"1.65"},1,1,"up","no"]
["ENSG00000184108","TRIML1","ENST00000507581","GO:0046872(metal ion binding);GO:0016740(transferase activity);GO:0016567(protein ubiquitination);GO:0007275(multicellular organism development)","NA","NA","NA","tripartite motif family like 1 [Source:HGNC Symbol;Acc:HGNC:26698]",0,0,1,0,1,1,"no","no"]
["ENSG00000259511","UBE2Q2L","ENST00000636149","NA","NA","NA","NA","ubiquitin conjugating enzyme E2 Q2 like [Source:HGNC Symbol;Acc:HGNC:44656]",0,0,1,0,1,1,"no","no"]
["ENSG00000215246","AC116351.1","ENST00000399869","NA","NA","NA","NA",null,{"v":0.030511,"d":"0.03"},0,"inf","inf",1,1,"up","no"]
["MSTRG.598","AL161644.1","ENST00000426901","NA","NA","NA","NA",null,{"v":0.198563,"d":"0.20"},{"v":0.457162,"d":"0.46"},{"v":0.434338374580564,"d":"0.43"},{"v":-1.20310867174948,"d":"-1.20"},1,1,"down","no"]
["ENSG00000261649","GOLGA6L7P","ENST00000567390","NA","NA","NA","NA","golgin A6 family-like 7, pseudogene [Source:HGNC Symbol;Acc:HGNC:37442]",0,{"v":0.00858231096121416,"d":"0.01"},"-inf","-inf",1,1,"down","no"]
["ENSG00000249307","LINC01088","ENST00000437737;ENST00000507761;ENST00000507476","NA","NA","NA","NA","long intergenic non-protein coding RNA 1088 [Source:HGNC Symbol;Acc:HGNC:49148]",{"v":0.411818932165206,"d":"0.41"},{"v":0.0254778185231539,"d":"0.03"},{"v":16.1638223378878,"d":"16.16"},{"v":4.01469649445277,"d":"4.01"},1,1,"up","no"]
["ENSG00000214193","SH3D21","ENST00000505871;ENST00000480549;ENST00000496636;ENST00000508854;ENST00000453908;ENST00000474766","GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005886(plasma membrane);GO:0070062(extracellular exosome);GO:0070062(extracellular exosome)","NA","NA","NA","SH3 domain containing 21 [Source:HGNC Symbol;Acc:HGNC:26236]",{"v":0.308959274027716,"d":"0.31"},{"v":0.140101573535986,"d":"0.14"},{"v":2.20525199132298,"d":"2.21"},{"v":1.14094352011849,"d":"1.14"},1,1,"up","no"]
["ENSG00000253111","AC091114.1","ENST00000521991","NA","NA","NA","NA",null,{"v":0.0325189717314488,"d":"0.03"},0,"inf","inf",1,1,"up","no"]
["MSTRG.9054","AC017002.1","ENST00000432268","NA","NA","NA","NA",null,0,{"v":0.00746,"d":"0.01"},"-inf","-inf",1,1,"down","no"]
["ENSG00000166634","SERPINB12","ENST00000382768","GO:0005737(cytoplasm);GO:0005615(extracellular space);GO:0010951(negative regulation of endopeptidase activity);GO:0005886(plasma membrane);GO:0030414(peptidase inhibitor activity);GO:0010466(negative regulation of peptidase activity);GO:0070062(extracellular exosome);GO:0004867(serine-type endopeptidase inhibitor activity);GO:0043312(neutrophil degranulation);GO:0019899(enzyme binding);GO:0042177(negative regulation of protein catabolic process);GO:0101003(ficolin-1-rich granule membrane);GO:0002244(hematopoietic progenitor cell differentiation)","NA","NA","NA","serpin family B member 12 [Source:HGNC Symbol;Acc:HGNC:14220]",0,0,1,0,1,1,"no","no"]
["MSTRG.9198","AC009299.2","ENST00000482477","NA","NA","NA","NA",null,0,{"v":0.049467,"d":"0.05"},"-inf","-inf",1,1,"down","no"]
["ENSG00000281732","Z84468.1","ENST00000626321;ENST00000625694","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["MSTRG.7745","AC020895.2","ENST00000624996","NA","NA","NA","NA",null,{"v":0.086655,"d":"0.09"},{"v":0.027674,"d":"0.03"},{"v":3.13127845631278,"d":"3.13"},{"v":1.64675180923632,"d":"1.65"},1,1,"up","no"]
["ENSG00000102683","SGCG","ENST00000218867","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005654(nucleoplasm);GO:0005886(plasma membrane);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0016012(sarcoglycan complex);GO:0042383(sarcolemma);GO:0007517(muscle organ development);GO:0055001(muscle cell development);GO:0061024(membrane organization);GO:0048738(cardiac muscle tissue development);GO:0060047(heart contraction);GO:0016011(dystroglycan complex)","05410(Hypertrophic cardiomyopathy (HCM));05412(Arrhythmogenic right ventricular cardiomyopathy (ARVC));05414(Dilated cardiomyopathy (DCM));05416(Viral myocarditis)","K12564","NA","sarcoglycan gamma [Source:HGNC Symbol;Acc:HGNC:10809]",0,0,1,0,1,1,"no","no"]
["ENSG00000186562","DEFB105A","ENST00000334773","GO:0005576(extracellular region);GO:0045087(innate immune response);GO:0042742(defense response to bacterium);GO:0006952(defense response);GO:0009986(cell surface)","NA","NA","NA","defensin beta 105A [Source:HGNC Symbol;Acc:HGNC:18087]",0,0,1,0,1,1,"no","no"]
["MSTRG.861","U1","ENST00000615842","NA","NA","NA","NA","U1 spliceosomal RNA [Source:RFAM;Acc:RF00003]",0,{"v":0.053226,"d":"0.05"},"-inf","-inf",1,1,"down","no"]
["MSTRG.315","AL512288.2","ENST00000426041","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000234665","AL512625.3","ENST00000585533;ENST00000591993;ENST00000612590;ENST00000586625;ENST00000445604;ENST00000609749","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000173769","TOPAZ1","ENST00000309765","GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0005829(cytosol);GO:0006915(apoptotic process);GO:0007286(spermatid development);GO:0048137(spermatocyte division);GO:0098781(ncRNA transcription);GO:1901995(positive regulation of meiotic cell cycle phase transition)","NA","NA","NA","testis and ovary specific PAZ domain containing 1 [Source:HGNC Symbol;Acc:HGNC:24746]",0,0,1,0,1,1,"no","no"]
["ENSG00000270002","AC022028.2","ENST00000474115","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000134757","DSG3","ENST00000257189","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0046872(metal ion binding);GO:0005509(calcium ion binding);GO:0007155(cell adhesion);GO:0007156(homophilic cell adhesion via plasma membrane adhesion molecules);GO:0005886(plasma membrane);GO:0030054(cell junction);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0031424(keratinization);GO:0070268(cornification);GO:0001533(cornified envelope);GO:0030057(desmosome)","NA","NA","NA","desmoglein 3 [Source:HGNC Symbol;Acc:HGNC:3050]",0,0,1,0,1,1,"no","no"]
["ENSG00000050628","PTGER3","ENST00000306666;ENST00000356595;ENST00000370924;ENST00000370932","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0004930(G-protein coupled receptor activity);GO:0007186(G-protein coupled receptor signaling pathway);GO:0005886(plasma membrane);GO:0004871(signal transducer activity);GO:0007165(signal transduction);GO:0004955(prostaglandin receptor activity);GO:0004957(prostaglandin E receptor activity);GO:0005887(integral component of plasma membrane);GO:0005635(nuclear envelope);GO:0007200(phospholipase C-activating G-protein coupled receptor signaling pathway);GO:0031622(positive regulation of fever generation);GO:0008219(cell death);GO:0014827(intestine smooth muscle contraction);GO:0060455(negative regulation of gastric acid secretion);GO:0008150(biological_process);GO:0008150(biological_process)","04020(Calcium signaling pathway);04024(cAMP signaling pathway);04080(Neuroactive ligand-receptor interaction);04923(Regulation of lipolysis in adipocyte);05200(Pathways in cancer);05200(Pathways in cancer)","K04260","NA","prostaglandin E receptor 3 [Source:HGNC Symbol;Acc:HGNC:9595]",{"v":0.0273507815186988,"d":"0.03"},{"v":0.0865710124313685,"d":"0.09"},{"v":0.31593463851866,"d":"0.32"},{"v":-1.66230197458153,"d":"-1.66"},1,1,"down","no"]
["ENSG00000231213","PLSCR5","ENST00000443512","GO:0005886(plasma membrane);GO:0017128(phospholipid scramblase activity);GO:0017121(phospholipid scrambling)","NA","NA","NA","phospholipid scramblase family member 5 [Source:HGNC Symbol;Acc:HGNC:19952]",0,0,1,0,1,1,"no","no"]
["MSTRG.5290","AC113208.4","ENST00000563568","NA","NA","NA","NA",null,{"v":0.002135,"d":"0.00"},{"v":0.000409,"d":"0.00"},{"v":5.2200488997555,"d":"5.22"},{"v":2.3840633215661,"d":"2.38"},1,1,"up","no"]
["MSTRG.7402","AP005899.1","ENST00000579467","NA","NA","NA","NA",null,{"v":0.448194,"d":"0.45"},0,"inf","inf",1,1,"up","no"]
["MSTRG.3173","KLRC3","MSTRG.3173.1","NA","NA","NA","NA",null,{"v":0.233404,"d":"0.23"},{"v":1.892596,"d":"1.89"},{"v":0.12332478775185,"d":"0.12"},{"v":-3.0194652905034,"d":"-3.02"},1,1,"down","no"]
["MSTRG.14698","AL356000.1","ENST00000441073","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000110680","CALCA","ENST00000494746","GO:0005737(cytoplasm);GO:0005576(extracellular region);GO:0005515(protein binding);GO:0005615(extracellular space);GO:0005179(hormone activity);GO:0005102(receptor binding);GO:0008217(regulation of blood pressure);GO:0051480(regulation of cytosolic calcium ion concentration);GO:0007267(cell-cell signaling);GO:0045671(negative regulation of osteoclast differentiation);GO:0006468(protein phosphorylation);GO:0032403(protein complex binding);GO:0043542(endothelial cell migration);GO:0030816(positive regulation of cAMP metabolic process);GO:0030819(positive regulation of cAMP biosynthetic process);GO:0031623(receptor internalization);GO:0097647(amylin receptor signaling pathway);GO:0001935(endothelial cell proliferation);GO:0045779(negative regulation of bone resorption);GO:0051482(positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway);GO:0097755(positive regulation of blood vessel diameter);GO:0032757(positive regulation of interleukin-8 production);GO:0007159(leukocyte cell-cell adhesion);GO:0001944(vasculature development);GO:0002031(G-protein coupled receptor internalization);GO:0007190(activation of adenylate cyclase activity);GO:0010523(negative regulation of calcium ion transport into cytosol);GO:0032730(positive regulation of interleukin-1 alpha production);GO:0045651(positive regulation of macrophage differentiation);GO:0042802(identical protein binding);GO:0044267(cellular protein metabolic process);GO:0007566(embryo implantation);GO:0045892(negative regulation of transcription, DNA-templated);GO:0007204(positive regulation of cytosolic calcium ion concentration);GO:0002548(monocyte chemotaxis);GO:0031716(calcitonin receptor binding);GO:0032147(activation of protein kinase activity);GO:0045762(positive regulation of adenylate cyclase activity);GO:0001984(artery vasodilation involved in baroreceptor response to increased systemic arterial blood pressure);GO:0002027(regulation of heart rate);GO:0006874(cellular calcium ion homeostasis);GO:0006954(inflammatory response);GO:0007189(adenylate cyclase-activating G-protein coupled receptor signaling pathway);GO:0007218(neuropeptide signaling pathway);GO:0007568(aging);GO:0007631(feeding behavior);GO:0008016(regulation of heart contraction);GO:0009408(response to heat);GO:0030279(negative regulation of ossification);GO:0031645(negative regulation of neurological system process);GO:0042311(vasodilation);GO:0045776(negative regulation of blood pressure);GO:0045778(positive regulation of ossification);GO:0045986(negative regulation of smooth muscle contraction);GO:0048265(response to pain);GO:0050965(detection of temperature stimulus involved in sensory perception of pain);GO:0071356(cellular response to tumor necrosis factor);GO:1990090(cellular response to nerve growth factor stimulus);GO:0005622(intracellular);GO:0005634(nucleus);GO:0030424(axon);GO:0043005(neuron projection);GO:0043025(neuronal cell body);GO:0043195(terminal bouton)","04270(Vascular smooth muscle contraction)","NA","NA","calcitonin related polypeptide alpha [Source:HGNC Symbol;Acc:HGNC:1437]",0,0,1,0,1,1,"no","no"]
["ENSG00000066813","ACSM2B","ENST00000329697","GO:0003674(molecular_function);GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0003824(catalytic activity);GO:0006629(lipid metabolic process);GO:0008152(metabolic process);GO:0006631(fatty acid metabolic process);GO:0005739(mitochondrion);GO:0016874(ligase activity);GO:0005759(mitochondrial matrix);GO:0006805(xenobiotic metabolic process);GO:0003996(acyl-CoA ligase activity);GO:0004321(fatty-acyl-CoA synthase activity);GO:0015645(fatty acid ligase activity);GO:0047760(butyrate-CoA ligase activity);GO:0006633(fatty acid biosynthetic process);GO:0006637(acyl-CoA metabolic process);GO:0016405(CoA-ligase activity);GO:0016020(membrane);GO:0016021(integral component of membrane)","00650(Butanoate metabolism)","K01896","EC:6.2.1.2","acyl-CoA synthetase medium chain family member 2B [Source:HGNC Symbol;Acc:HGNC:30931]",0,0,1,0,1,1,"no","no"]
["ENSG00000229559","AL353597.2","ENST00000445172;ENST00000434901","NA","NA","NA","NA",null,{"v":0.217739442205726,"d":"0.22"},{"v":0.00929233297985154,"d":"0.01"},{"v":23.4321609737671,"d":"23.43"},{"v":4.5504181042474,"d":"4.55"},1,1,"up","no"]
["ENSG00000279989","AC011815.3","ENST00000624194","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["MSTRG.8091","AD001527.1","ENST00000604228","NA","NA","NA","NA",null,{"v":0.021349,"d":"0.02"},0,"inf","inf",1,1,"up","no"]
["MSTRG.6207","AC018695.4","ENST00000602706","NA","NA","NA","NA",null,{"v":0.609952,"d":"0.61"},{"v":0.073863,"d":"0.07"},{"v":8.25788283714444,"d":"8.26"},{"v":3.04577194969963,"d":"3.05"},1,1,"up","no"]
["MSTRG.10608","U62317.2","ENST00000609178","NA","NA","NA","NA",null,{"v":0.216458,"d":"0.22"},{"v":0.196451,"d":"0.20"},{"v":1.10184218965544,"d":"1.10"},{"v":0.13991761002087,"d":"0.14"},1,1,"up","no"]
["ENSG00000150764","DIXDC1","ENST00000528399;ENST00000440460;ENST00000618522;ENST00000615255;ENST00000526418;ENST00000529225","GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0003779(actin binding);GO:0005515(protein binding);GO:0007275(multicellular organism development);GO:0016055(Wnt signaling pathway);GO:0030054(cell junction);GO:0005925(focal adhesion);GO:0090263(positive regulation of canonical Wnt signaling pathway);GO:0043015(gamma-tubulin binding);GO:0019904(protein domain specific binding);GO:0007049(cell cycle);GO:0021795(cerebral cortex cell migration);GO:0021799(cerebral cortex radially oriented cell migration);GO:0021846(cell proliferation in forebrain);GO:0021869(forebrain ventricular zone progenitor cell division);GO:0030177(positive regulation of Wnt signaling pathway);GO:0032956(regulation of actin cytoskeleton organization);GO:0045665(negative regulation of neuron differentiation);GO:0060070(canonical Wnt signaling pathway);GO:0070507(regulation of microtubule cytoskeleton organization);GO:0070507(regulation of microtubule cytoskeleton organization)","NA","NA","NA","DIX domain containing 1 [Source:HGNC Symbol;Acc:HGNC:23695]",{"v":0.147975956751675,"d":"0.15"},{"v":0.0128233140204489,"d":"0.01"},{"v":11.5396032972212,"d":"11.54"},{"v":3.52852172346616,"d":"3.53"},1,1,"up","no"]
["ENSG00000236745","YRDCP2","ENST00000424606","NA","NA","NA","NA","yrdC N(6)-threonylcarbamoyltransferase domain containing pseudogene 2 [Source:HGNC Symbol;Acc:HGNC:39920]",0,0,1,0,1,1,"no","no"]
["ENSG00000236882","LINC01554","ENST00000436592","NA","NA","NA","NA","long intergenic non-protein coding RNA 1554 [Source:HGNC Symbol;Acc:HGNC:24687]",0,{"v":0.0233027947598253,"d":"0.02"},"-inf","-inf",1,1,"down","no"]
["ENSG00000217026","RPL10P1","ENST00000447844","NA","NA","NA","NA","ribosomal protein L10 pseudogene 1 [Source:HGNC Symbol;Acc:HGNC:10300]",0,0,1,0,1,1,"no","no"]
["ENSG00000215354","FAM90A24P","ENST00000520792","NA","NA","NA","NA","family with sequence similarity 90 member A24, pseudogene [Source:HGNC Symbol;Acc:HGNC:32272]",0,0,1,0,1,1,"no","no"]
["ENSG00000234723","AC092421.1","ENST00000448148","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000215644","GCGR","ENST00000400723","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0004930(G-protein coupled receptor activity);GO:0007186(G-protein coupled receptor signaling pathway);GO:0005886(plasma membrane);GO:0043547(positive regulation of GTPase activity);GO:0004871(signal transducer activity);GO:0007165(signal transduction);GO:0004888(transmembrane signaling receptor activity);GO:0007166(cell surface receptor signaling pathway);GO:0005887(integral component of plasma membrane);GO:0004967(glucagon receptor activity);GO:0006091(generation of precursor metabolites and energy);GO:0005085(guanyl-nucleotide exchange factor activity);GO:0007584(response to nutrient);GO:0042593(glucose homeostasis);GO:0007189(adenylate cyclase-activating G-protein coupled receptor signaling pathway);GO:0071377(cellular response to glucagon stimulus);GO:0007188(adenylate cyclase-modulating G-protein coupled receptor signaling pathway);GO:0042594(response to starvation);GO:0008217(regulation of blood pressure);GO:0017046(peptide hormone binding);GO:0006887(exocytosis);GO:0009755(hormone-mediated signaling pathway);GO:0070873(regulation of glycogen metabolic process);GO:0005768(endosome)","04080(Neuroactive ligand-receptor interaction);04922(Glucagon signaling pathway)","K04583","NA","glucagon receptor [Source:HGNC Symbol;Acc:HGNC:4192]",0,0,1,0,1,1,"no","no"]
["ENSG00000228818","AL359918.1","ENST00000451892","NA","NA","NA","NA",null,{"v":0.008989,"d":"0.01"},0,"inf","inf",1,1,"up","no"]
["ENSG00000226673","LINC01108","ENST00000427276","NA","NA","NA","NA","long intergenic non-protein coding RNA 1108 [Source:HGNC Symbol;Acc:HGNC:49234]",0,0,1,0,1,1,"no","no"]
["MSTRG.14149","AC093583.1","ENST00000462083","NA","NA","NA","NA",null,{"v":0.0961864548117155,"d":"0.10"},{"v":0.0655953154811715,"d":"0.07"},{"v":1.46636164650088,"d":"1.47"},{"v":0.552240956997941,"d":"0.55"},1,1,"up","no"]
["MSTRG.7371","NARF-IT1","ENST00000584012","NA","NA","NA","NA","NARF intronic transcript 1 [Source:HGNC Symbol;Acc:HGNC:43651]",{"v":0.524038,"d":"0.52"},{"v":0.195575,"d":"0.20"},{"v":2.67947334782053,"d":"2.68"},{"v":1.42194946592479,"d":"1.42"},1,1,"up","no"]
["ENSG00000279406","AL359183.1","ENST00000623796","NA","NA","NA","NA",null,{"v":0.149493,"d":"0.15"},{"v":0.047741,"d":"0.05"},{"v":3.1313336545108,"d":"3.13"},{"v":1.6467772408502,"d":"1.65"},1,1,"up","no"]
["MSTRG.10878","CCR5","ENST00000292303","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0004930(G-protein coupled receptor activity);GO:0007186(G-protein coupled receptor signaling pathway);GO:0003779(actin binding);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0004871(signal transducer activity);GO:0007165(signal transduction);GO:0006955(immune response);GO:0006816(calcium ion transport);GO:0004950(chemokine receptor activity);GO:0016493(C-C chemokine receptor activity);GO:0006935(chemotaxis);GO:0006954(inflammatory response);GO:0070098(chemokine-mediated signaling pathway);GO:0005768(endosome);GO:0071222(cellular response to lipopolysaccharide);GO:0016032(viral process);GO:0005887(integral component of plasma membrane);GO:0005737(cytoplasm);GO:0009986(cell surface);GO:0007166(cell surface receptor signaling pathway);GO:0004435(phosphatidylinositol phospholipase C activity);GO:0000165(MAPK cascade);GO:0015026(coreceptor activity);GO:0002407(dendritic cell chemotaxis);GO:0007267(cell-cell signaling);GO:0019722(calcium-mediated signaling);GO:0001618(virus receptor activity);GO:0007204(positive regulation of cytosolic calcium ion concentration);GO:0006968(cellular defense response);GO:0014808(release of sequestered calcium ion into cytosol by sarcoplasmic reticulum);GO:0009897(external side of plasma membrane);GO:0019064(fusion of virus membrane with host plasma membrane);GO:0030260(entry into host cell);GO:0023052(signaling);GO:0070723(response to cholesterol);GO:0019957(C-C chemokine binding);GO:0071791(chemokine (C-C motif) ligand 5 binding)","04060(Cytokine-cytokine receptor interaction);04144(Endocytosis);04062(Chemokine signaling pathway);05203(Viral carcinogenesis);05167(Kaposi's sarcoma-associated herpesvirus infection);05145(Toxoplasmosis)","K04180","NA","C-C motif chemokine receptor 5 (gene/pseudogene) [Source:HGNC Symbol;Acc:HGNC:1606]",{"v":0.016669362745098,"d":"0.02"},{"v":5.17817565359477,"d":"5.18"},{"v":3.21915745239849E-3,"d":"0.00"},{"v":-8.27910114237922,"d":"-8.28"},1,1,"down","no"]
["ENSG00000237422","AL158071.3","ENST00000457976","NA","NA","NA","NA",null,{"v":0.151802,"d":"0.15"},{"v":0.100577,"d":"0.10"},{"v":1.50931127394931,"d":"1.51"},{"v":0.593890371850251,"d":"0.59"},1,1,"up","no"]
["ENSG00000236846","AL359979.2","ENST00000435108","NA","NA","NA","NA",null,{"v":0.129983,"d":"0.13"},0,"inf","inf",1,1,"up","no"]
["ENSG00000229203","AC103564.1","ENST00000437330","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000236731","AL135929.2","ENST00000445687","NA","NA","NA","NA",null,{"v":0.203538,"d":"0.20"},0,"inf","inf",1,1,"up","no"]
["ENSG00000251686","OR10J8P","ENST00000504659","NA","NA","NA","NA","olfactory receptor family 10 subfamily J member 8 pseudogene [Source:HGNC Symbol;Acc:HGNC:19638]",0,0,1,0,1,1,"no","no"]
["ENSG00000108700","CCL8","ENST00000394620","GO:0005623(cell);GO:0006468(protein phosphorylation);GO:0005576(extracellular region);GO:0006955(immune response);GO:0006816(calcium ion transport);GO:0005125(cytokine activity);GO:0005615(extracellular space);GO:0008009(chemokine activity);GO:0006935(chemotaxis);GO:0006954(inflammatory response);GO:0007186(G-protein coupled receptor signaling pathway);GO:0048020(CCR chemokine receptor binding);GO:0002548(monocyte chemotaxis);GO:0030593(neutrophil chemotaxis);GO:0043547(positive regulation of GTPase activity);GO:0048247(lymphocyte chemotaxis);GO:0070098(chemokine-mediated signaling pathway);GO:0070374(positive regulation of ERK1 and ERK2 cascade);GO:0071346(cellular response to interferon-gamma);GO:0071347(cellular response to interleukin-1);GO:0071356(cellular response to tumor necrosis factor);GO:0006887(exocytosis);GO:0008201(heparin binding);GO:0007165(signal transduction);GO:0004672(protein kinase activity);GO:0009615(response to virus);GO:0007267(cell-cell signaling);GO:0006874(cellular calcium ion homeostasis);GO:0016004(phospholipase activator activity);GO:0002687(positive regulation of leukocyte migration);GO:0070664(negative regulation of leukocyte proliferation)","04060(Cytokine-cytokine receptor interaction);04062(Chemokine signaling pathway)","K16596","NA","C-C motif chemokine ligand 8 [Source:HGNC Symbol;Acc:HGNC:10635]",0,{"v":0.040358,"d":"0.04"},"-inf","-inf",1,1,"down","no"]
["ENSG00000272699","AC007620.3","ENST00000608131","NA","NA","NA","NA",null,{"v":0.205268,"d":"0.21"},{"v":0.102398,"d":"0.10"},{"v":2.00460946502861,"d":"2.00"},{"v":1.00332120039813,"d":"1.00"},1,1,"up","no"]
["ENSG00000156869","FRRS1","ENST00000370176;ENST00000492943;ENST00000287474","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0046872(metal ion binding);GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0000293(ferric-chelate reductase activity);GO:0000293(ferric-chelate reductase activity)","NA","NA","NA","ferric chelate reductase 1 [Source:HGNC Symbol;Acc:HGNC:27622]",{"v":0.171576737849018,"d":"0.17"},{"v":0.167518797311272,"d":"0.17"},{"v":1.02422379221244,"d":"1.02"},{"v":0.0345309776814011,"d":"0.03"},1,1,"up","no"]
["MSTRG.3272","REP15","ENST00000310791","GO:0016020(membrane);GO:0048471(perinuclear region of cytoplasm);GO:0005515(protein binding);GO:0005768(endosome);GO:0010008(endosome membrane);GO:0031901(early endosome membrane);GO:0055037(recycling endosome);GO:0033572(transferrin transport);GO:0001881(receptor recycling)","NA","NA","NA","RAB15 effector protein [Source:HGNC Symbol;Acc:HGNC:33748]",0,{"v":0.090198,"d":"0.09"},"-inf","-inf",1,1,"down","no"]
["MSTRG.8696","AC008280.1","ENST00000418851","NA","NA","NA","NA",null,{"v":0.22692,"d":"0.23"},0,"inf","inf",1,1,"up","no"]
["ENSG00000280076","AC112693.3","ENST00000624819","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["MSTRG.6365","AC055839.1","ENST00000634467","NA","NA","NA","NA",null,0,{"v":0.102192,"d":"0.10"},"-inf","-inf",1,1,"down","no"]
["ENSG00000166984","TCP10L2","ENST00000539001;ENST00000283507;ENST00000366832;ENST00000464222","NA","NA","NA","NA","t-complex 10 like 2 [Source:HGNC Symbol;Acc:HGNC:21254]",0,0,1,0,1,1,"no","no"]
["ENSG00000131737","KRT34","ENST00000394001","GO:0005198(structural molecule activity);GO:0005882(intermediate filament);GO:0005615(extracellular space);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0031424(keratinization);GO:0008544(epidermis development);GO:0070268(cornification)","NA","NA","NA","keratin 34 [Source:HGNC Symbol;Acc:HGNC:6452]",0,0,1,0,1,1,"no","no"]
["ENSG00000261040","WFDC21P","ENST00000592556;ENST00000589777;ENST00000588180;ENST00000590346","NA","NA","NA","NA","WAP four-disulfide core domain 21, pseudogene [Source:HGNC Symbol;Acc:HGNC:50357]",{"v":0.0547248425841674,"d":"0.05"},{"v":0.137060282074613,"d":"0.14"},{"v":0.399275718361474,"d":"0.40"},{"v":-1.32454275661201,"d":"-1.32"},1,1,"down","no"]
["ENSG00000228383","FAM197Y7","ENST00000432892","NA","NA","NA","NA","family with sequence similarity 197 Y-linked member 7 [Source:HGNC Symbol;Acc:HGNC:37469]",0,0,1,0,1,1,"no","no"]
["MSTRG.701","AC099568.1","ENST00000432395","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000228283","KATNBL1P6","ENST00000562413","NA","NA","NA","NA","katanin regulatory subunit B1 like 1 pseudogene 6 [Source:HGNC Symbol;Acc:HGNC:49056]",0,{"v":0.008679,"d":"0.01"},"-inf","-inf",1,1,"down","no"]
["ENSG00000181449","SOX2","ENST00000325404","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005654(nucleoplasm);GO:0006355(regulation of transcription, DNA-templated);GO:0006366(transcription from RNA polymerase II promoter);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0005829(cytosol);GO:0005515(protein binding);GO:0007275(multicellular organism development);GO:0045893(positive regulation of transcription, DNA-templated);GO:0006325(chromatin organization);GO:0000976(transcription regulatory region sequence-specific DNA binding);GO:0001077(transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0021984(adenohypophysis development);GO:0022409(positive regulation of cell-cell adhesion);GO:0042246(tissue regeneration);GO:0045597(positive regulation of cell differentiation);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0001654(eye development);GO:0090090(negative regulation of canonical Wnt signaling pathway);GO:0007050(cell cycle arrest);GO:0005667(transcription factor complex);GO:0044212(transcription regulatory region DNA binding);GO:0045665(negative regulation of neuron differentiation);GO:0097150(neuronal stem cell population maintenance);GO:0050680(negative regulation of epithelial cell proliferation);GO:0035019(somatic stem cell population maintenance);GO:0043410(positive regulation of MAPK cascade);GO:0001649(osteoblast differentiation);GO:0009611(response to wounding);GO:0021983(pituitary gland development);GO:0048839(inner ear development);GO:0043565(sequence-specific DNA binding);GO:0010468(regulation of gene expression);GO:0070848(response to growth factor);GO:0035198(miRNA binding);GO:0030900(forebrain development);GO:0001714(endodermal cell fate specification);GO:0021781(glial cell fate commitment);GO:0043281(regulation of cysteine-type endopeptidase activity involved in apoptotic process)","04390(Hippo signaling pathway);04550(Signaling pathways regulating pluripotency of stem cells)","K16796","NA","SRY-box 2 [Source:HGNC Symbol;Acc:HGNC:11195]",{"v":0.020998,"d":"0.02"},0,"inf","inf",1,1,"up","no"]
["ENSG00000274678","AC106886.3","ENST00000621583","NA","NA","NA","NA",null,{"v":0.097111,"d":"0.10"},0,"inf","inf",1,1,"up","no"]
["ENSG00000214686","IQCF6","ENST00000398780","GO:0005516(calmodulin binding)","NA","NA","NA","IQ motif containing F6 [Source:HGNC Symbol;Acc:HGNC:35158]",0,0,1,0,1,1,"no","no"]
["MSTRG.537","AL135960.1","ENST00000422216","NA","NA","NA","NA",null,{"v":0.013162,"d":"0.01"},{"v":0.090961,"d":"0.09"},{"v":0.144699376655929,"d":"0.14"},{"v":-2.78886938792675,"d":"-2.79"},1,1,"down","no"]
["ENSG00000274225","AP001065.2","ENST00000617205","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000255421","AP002340.1","ENST00000529298","NA","NA","NA","NA",null,{"v":0.296725,"d":"0.30"},{"v":0.03666,"d":"0.04"},{"v":8.09397163120567,"d":"8.09"},{"v":3.01684779247279,"d":"3.02"},1,1,"up","no"]
["ENSG00000090932","DLL3","ENST00000205143;ENST00000356433","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005509(calcium ion binding);GO:0007275(multicellular organism development);GO:0030154(cell differentiation);GO:0007219(Notch signaling pathway);GO:0001501(skeletal system development);GO:0005112(Notch binding);GO:0001756(somitogenesis);GO:0007386(compartment pattern specification);GO:0009888(tissue development);GO:0048339(paraxial mesoderm development);GO:0050768(negative regulation of neurogenesis);GO:0050768(negative regulation of neurogenesis)","04330(Notch signaling pathway);04658(Th1 and Th2 cell differentiation);05200(Pathways in cancer);05224(Breast cancer);01522(Endocrine resistance);01522(Endocrine resistance)","K06051","NA","delta like canonical Notch ligand 3 [Source:HGNC Symbol;Acc:HGNC:2909]",0,{"v":0.0583178151260504,"d":"0.06"},"-inf","-inf",1,1,"down","no"]
["ENSG00000214070","AC011999.1","ENST00000424794","NA","NA","NA","NA",null,{"v":0.051875,"d":"0.05"},0,"inf","inf",1,1,"up","no"]
["MSTRG.12646","C6orf201","ENST00000436110;ENST00000496987","NA","NA","NA","NA","chromosome 6 open reading frame 201 [Source:HGNC Symbol;Acc:HGNC:21620]",{"v":0.107351900572462,"d":"0.11"},{"v":0.0153332160289244,"d":"0.02"},{"v":7.00126446858602,"d":"7.00"},{"v":2.80761550460248,"d":"2.81"},1,1,"up","no"]
["ENSG00000233347","ERP29P1","ENST00000442902","NA","NA","NA","NA","endoplasmic reticulum lumenal protein 29 pseudogene 1 [Source:HGNC Symbol;Acc:HGNC:24625]",0,0,1,0,1,1,"no","no"]
["ENSG00000261168","AL592424.1","ENST00000563624","NA","NA","NA","NA",null,{"v":0.034583,"d":"0.03"},{"v":0.063413,"d":"0.06"},{"v":0.545361361235078,"d":"0.55"},{"v":-0.874715605725527,"d":"-0.87"},1,1,"down","no"]
["ENSG00000171903","CYP4F11","ENST00000402119","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0046872(metal ion binding);GO:0004497(monooxygenase activity);GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0005783(endoplasmic reticulum);GO:0005506(iron ion binding);GO:0016705(oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen);GO:0020037(heme binding);GO:0006954(inflammatory response);GO:0005789(endoplasmic reticulum membrane);GO:0043231(intracellular membrane-bounded organelle);GO:0016709(oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen);GO:0007596(blood coagulation);GO:0031090(organelle membrane);GO:0005504(fatty acid binding);GO:0006631(fatty acid metabolic process);GO:0042361(menaquinone catabolic process);GO:0042376(phylloquinone catabolic process);GO:0042377(vitamin K catabolic process)","NA","NA","NA","cytochrome P450 family 4 subfamily F member 11 [Source:HGNC Symbol;Acc:HGNC:13265]",0,0,1,0,1,1,"no","no"]
["ENSG00000002746","HECW1","ENST00000395891","GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0016740(transferase activity);GO:0016567(protein ubiquitination);GO:0004842(ubiquitin-protein transferase activity);GO:0061630(ubiquitin protein ligase activity);GO:0043161(proteasome-mediated ubiquitin-dependent protein catabolic process);GO:0090090(negative regulation of canonical Wnt signaling pathway);GO:0042787(protein ubiquitination involved in ubiquitin-dependent protein catabolic process)","NA","NA","NA","HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1 [Source:HGNC Symbol;Acc:HGNC:22195]",0,0,1,0,1,1,"no","no"]
["ENSG00000259056","DUXAP1","ENST00000556632","NA","NA","NA","NA","double homeobox A pseudogene 1 [Source:HGNC Symbol;Acc:HGNC:32180]",0,0,1,0,1,1,"no","no"]
["ENSG00000162706","CADM3","ENST00000368125","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0007155(cell adhesion);GO:0005886(plasma membrane);GO:0030054(cell junction);GO:0005887(integral component of plasma membrane);GO:0004872(receptor activity);GO:0005102(receptor binding);GO:0042803(protein homodimerization activity);GO:0050839(cell adhesion molecule binding);GO:0007156(homophilic cell adhesion via plasma membrane adhesion molecules);GO:0007157(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules);GO:0005913(cell-cell adherens junction);GO:0034332(adherens junction organization);GO:0008037(cell recognition);GO:0005911(cell-cell junction);GO:0008104(protein localization)","04514(Cell adhesion molecules (CAMs))","K06780","NA","cell adhesion molecule 3 [Source:HGNC Symbol;Acc:HGNC:17601]",0,0,1,0,1,1,"no","no"]
["ENSG00000243141","RPL23AP66","ENST00000494341","NA","NA","NA","NA","ribosomal protein L23a pseudogene 66 [Source:HGNC Symbol;Acc:HGNC:35940]",0,{"v":0.106246,"d":"0.11"},"-inf","-inf",1,1,"down","no"]
["ENSG00000235641","LINC00484","ENST00000588550;ENST00000608240","NA","NA","NA","NA","long intergenic non-protein coding RNA 484 [Source:HGNC Symbol;Acc:HGNC:27862]",0,{"v":0.0412970992696781,"d":"0.04"},"-inf","-inf",1,1,"down","no"]
["MSTRG.1804","DUSP8P5","ENST00000422884","NA","NA","NA","NA","dual specificity phosphatase 8 pseudogene 5 [Source:HGNC Symbol;Acc:HGNC:45003]",0,{"v":0.154218,"d":"0.15"},"-inf","-inf",1,1,"down","no"]
["ENSG00000219074","SOD1P1","ENST00000407803","NA","NA","NA","NA","superoxide dismutase 1 pseudogene 1 [Source:HGNC Symbol;Acc:HGNC:45134]",0,0,1,0,1,1,"no","no"]
["ENSG00000105737","GRIK5","ENST00000301218;ENST00000262895","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005216(ion channel activity);GO:0006811(ion transport);GO:0034220(ion transmembrane transport);GO:0005886(plasma membrane);GO:0035725(sodium ion transmembrane transport);GO:0071805(potassium ion transmembrane transport);GO:0030054(cell junction);GO:0045202(synapse);GO:0045211(postsynaptic membrane);GO:0004872(receptor activity);GO:0004970(ionotropic glutamate receptor activity);GO:0005234(extracellular-glutamate-gated ion channel activity);GO:0035235(ionotropic glutamate receptor signaling pathway);GO:0015276(ligand-gated ion channel activity);GO:0015277(kainate selective glutamate receptor activity);GO:0008066(glutamate receptor activity);GO:0017124(SH3 domain binding);GO:0030165(PDZ domain binding);GO:0042802(identical protein binding);GO:0006621(protein retention in ER lumen);GO:0007268(chemical synaptic transmission);GO:0031630(regulation of synaptic vesicle fusion to presynaptic active zone membrane);GO:0035249(synaptic transmission, glutamatergic);GO:0042391(regulation of membrane potential);GO:0043113(receptor clustering);GO:0043525(positive regulation of neuron apoptotic process);GO:0051649(establishment of localization in cell);GO:0060079(excitatory postsynaptic potential);GO:0071333(cellular response to glucose stimulus);GO:0005783(endoplasmic reticulum);GO:0008328(ionotropic glutamate receptor complex);GO:0014069(postsynaptic density);GO:0030424(axon);GO:0030425(dendrite);GO:0032983(kainate selective glutamate receptor complex);GO:0042734(presynaptic membrane);GO:0043005(neuron projection);GO:0043025(neuronal cell body);GO:0043195(terminal bouton);GO:0043204(perikaryon);GO:0043204(perikaryon)","04080(Neuroactive ligand-receptor interaction);04724(Glutamatergic synapse);04724(Glutamatergic synapse)","K05205","NA","glutamate ionotropic receptor kainate type subunit 5 [Source:HGNC Symbol;Acc:HGNC:4583]",{"v":0.0846143372556841,"d":"0.08"},0,"inf","inf",1,1,"up","no"]
["ENSG00000132622","HSPA12B","ENST00000254963","GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0005515(protein binding)","NA","NA","NA","heat shock protein family A (Hsp70) member 12B [Source:HGNC Symbol;Acc:HGNC:16193]",{"v":0.016858,"d":"0.02"},0,"inf","inf",1,1,"up","no"]
["ENSG00000233330","AL078581.1","ENST00000419134","NA","NA","NA","NA",null,0,{"v":0.149682,"d":"0.15"},"-inf","-inf",1,1,"down","no"]
["ENSG00000117245","KIF17","ENST00000247986;ENST00000400463","GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0003777(microtubule motor activity);GO:0008017(microtubule binding);GO:0005874(microtubule);GO:0007018(microtubule-based movement);GO:0006810(transport);GO:0005737(cytoplasm);GO:0015031(protein transport);GO:0005856(cytoskeleton);GO:0042995(cell projection);GO:0035735(intraciliary transport involved in cilium assembly);GO:0005929(cilium);GO:0005829(cytosol);GO:0005871(kinesin complex);GO:0008574(ATP-dependent microtubule motor activity, plus-end-directed);GO:0032839(dendrite cytoplasm);GO:0022008(neurogenesis);GO:0030030(cell projection organization);GO:0007017(microtubule-based process);GO:0016192(vesicle-mediated transport);GO:0031503(protein complex localization);GO:0098971(anterograde dendritic transport of neurotransmitter receptor complex);GO:0005930(axoneme);GO:0015630(microtubule cytoskeleton);GO:0030992(intraciliary transport particle B);GO:0032391(photoreceptor connecting cilium);GO:0036064(ciliary basal body);GO:1990075(periciliary membrane compartment);GO:1990075(periciliary membrane compartment)","NA","NA","NA","kinesin family member 17 [Source:HGNC Symbol;Acc:HGNC:19167]",{"v":0.0118839140939597,"d":"0.01"},{"v":0.0227698787472036,"d":"0.02"},{"v":0.521913806652096,"d":"0.52"},{"v":-0.938116527523597,"d":"-0.94"},1,1,"down","no"]
["ENSG00000145794","MEGF10","ENST00000274473","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0007155(cell adhesion);GO:0005886(plasma membrane);GO:0042995(cell projection);GO:0006898(receptor-mediated endocytosis);GO:0001891(phagocytic cup);GO:0034109(homotypic cell-cell adhesion);GO:0016323(basolateral plasma membrane);GO:0007517(muscle organ development);GO:0006909(phagocytosis);GO:0005112(Notch binding);GO:0043652(engulfment of apoptotic cell);GO:0051451(myoblast migration);GO:1902742(apoptotic process involved in development);GO:0051147(regulation of muscle cell differentiation);GO:0014719(skeletal muscle satellite cell activation);GO:0001849(complement component C1q binding);GO:0005044(scavenger receptor activity);GO:0014816(skeletal muscle satellite cell differentiation);GO:0014841(skeletal muscle satellite cell proliferation);GO:0033002(muscle cell proliferation);GO:0048641(regulation of skeletal muscle tissue development);GO:0055001(muscle cell development);GO:0043654(recognition of apoptotic cell)","NA","NA","NA","multiple EGF like domains 10 [Source:HGNC Symbol;Acc:HGNC:29634]",0,0,1,0,1,1,"no","no"]
["ENSG00000181656","GPR88","ENST00000315033","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0004930(G-protein coupled receptor activity);GO:0007186(G-protein coupled receptor signaling pathway);GO:0005886(plasma membrane);GO:0004871(signal transducer activity);GO:0007165(signal transduction);GO:0003774(motor activity);GO:0005575(cellular_component);GO:0007268(chemical synaptic transmission);GO:0007631(feeding behavior);GO:0007218(neuropeptide signaling pathway);GO:0007626(locomotory behavior);GO:0019228(neuronal action potential);GO:0050885(neuromuscular process controlling balance);GO:0061743(motor learning)","NA","NA","NA","G protein-coupled receptor 88 [Source:HGNC Symbol;Acc:HGNC:4539]",{"v":0.088041,"d":"0.09"},{"v":0.081231,"d":"0.08"},{"v":1.08383498910514,"d":"1.08"},{"v":0.116145127060049,"d":"0.12"},1,1,"up","no"]
["ENSG00000197083","ZNF300P1","ENST00000520773","NA","NA","NA","NA","zinc finger protein 300 pseudogene 1 [Source:HGNC Symbol;Acc:HGNC:27032]",{"v":0.0169875583626479,"d":"0.02"},{"v":0.0416057211384714,"d":"0.04"},{"v":0.408298616099219,"d":"0.41"},{"v":-1.29230341723411,"d":"-1.29"},1,1,"down","no"]
["MSTRG.2852","AP003170.3","ENST00000399123","NA","NA","NA","NA",null,{"v":0.026718,"d":"0.03"},0,"inf","inf",1,1,"up","no"]
["ENSG00000163218","PGLYRP4","ENST00000368739","GO:0016020(membrane);GO:0008270(zinc ion binding);GO:0005576(extracellular region);GO:0002376(immune system process);GO:0045087(innate immune response);GO:0042742(defense response to bacterium);GO:0005622(intracellular);GO:0002221(pattern recognition receptor signaling pathway);GO:0043234(protein complex);GO:0050830(defense response to Gram-positive bacterium);GO:0061844(antimicrobial humoral immune response mediated by antimicrobial peptide);GO:0009253(peptidoglycan catabolic process);GO:0046982(protein heterodimerization activity);GO:0031640(killing of cells of other organism);GO:0042834(peptidoglycan binding);GO:0008745(N-acetylmuramoyl-L-alanine amidase activity);GO:0016019(peptidoglycan receptor activity);GO:0016045(detection of bacterium);GO:0051714(positive regulation of cytolysis in other organism)","NA","NA","NA","peptidoglycan recognition protein 4 [Source:HGNC Symbol;Acc:HGNC:30015]",0,0,1,0,1,1,"no","no"]
["ENSG00000280067","AC023818.2","ENST00000623817","NA","NA","NA","NA",null,{"v":0.276055,"d":"0.28"},{"v":0.066265,"d":"0.07"},{"v":4.16592469629518,"d":"4.17"},{"v":2.05863676130285,"d":"2.06"},1,1,"up","no"]
["ENSG00000087510","TFAP2C","ENST00000201031","GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0006355(regulation of transcription, DNA-templated);GO:0006366(transcription from RNA polymerase II promoter);GO:0006351(transcription, DNA-templated);GO:0005739(mitochondrion);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0005515(protein binding);GO:0001047(core promoter binding);GO:0005829(cytosol);GO:0008584(male gonad development);GO:0000977(RNA polymerase II regulatory region sequence-specific DNA binding);GO:0007267(cell-cell signaling);GO:0042127(regulation of cell proliferation);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0001078(transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0001077(transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0046983(protein dimerization activity);GO:0040029(regulation of gene expression, epigenetic);GO:0000122(negative regulation of transcription from RNA polymerase II promoter)","NA","NA","NA","transcription factor AP-2 gamma [Source:HGNC Symbol;Acc:HGNC:11744]",0,0,1,0,1,1,"no","no"]
["ENSG00000229842","MTATP6P13","ENST00000438531","NA","NA","NA","NA","mitochondrially encoded ATP synthase 6 pseudogene 13 [Source:HGNC Symbol;Acc:HGNC:52058]",0,0,1,0,1,1,"no","no"]
["ENSG00000258576","AL163974.1","ENST00000554540","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000139410","SDSL","ENST00000403593","GO:0016829(lyase activity);GO:0030170(pyridoxal phosphate binding);GO:0006520(cellular amino acid metabolic process);GO:0005739(mitochondrion);GO:0042802(identical protein binding);GO:0003674(molecular_function);GO:0008150(biological_process);GO:0070062(extracellular exosome);GO:0003941(L-serine ammonia-lyase activity);GO:0004794(L-threonine ammonia-lyase activity)","00260(Glycine, serine and threonine metabolism);00270(Cysteine and methionine metabolism);00290(Valine, leucine and isoleucine biosynthesis)","K17989","EC:4.3.1.17;EC:4.3.1.19","serine dehydratase like [Source:HGNC Symbol;Acc:HGNC:30404]",{"v":0.287652001353791,"d":"0.29"},{"v":0.457385742779783,"d":"0.46"},{"v":0.628904608188206,"d":"0.63"},{"v":-0.669086888165055,"d":"-0.67"},1,1,"down","no"]
["ENSG00000166352","C11orf74","ENST00000534635;ENST00000531554;ENST00000446510;ENST00000530697;ENST00000524539;ENST00000334307","GO:0005929(cilium);GO:0005929(cilium)","NA","NA","NA","chromosome 11 open reading frame 74 [Source:HGNC Symbol;Acc:HGNC:25142]",{"v":0.272074270013568,"d":"0.27"},{"v":0.927552365671642,"d":"0.93"},{"v":0.293324970193525,"d":"0.29"},{"v":-1.76942820469607,"d":"-1.77"},1,1,"down","no"]
["ENSG00000266527","AC005697.2","ENST00000581901","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000224124","POM121L10P","ENST00000436994","NA","NA","NA","NA","POM121 transmembrane nucleoporin like 10, pseudogene [Source:HGNC Symbol;Acc:HGNC:35448]",0,0,1,0,1,1,"no","no"]
["ENSG00000248358","AC243972.1","ENST00000542992","NA","NA","NA","NA",null,{"v":0.065664,"d":"0.07"},0,"inf","inf",1,1,"up","no"]
["ENSG00000142677","IL22RA1","ENST00000270800","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005515(protein binding);GO:0019221(cytokine-mediated signaling pathway);GO:0005886(plasma membrane);GO:0008150(biological_process);GO:0004904(interferon receptor activity);GO:0042015(interleukin-20 binding);GO:0050829(defense response to Gram-negative bacterium)","04630(Jak-STAT signaling pathway);04060(Cytokine-cytokine receptor interaction)","K05138","NA","interleukin 22 receptor subunit alpha 1 [Source:HGNC Symbol;Acc:HGNC:13700]",0,0,1,0,1,1,"no","no"]
["ENSG00000240184","PCDHGC3","ENST00000622836;ENST00000611950","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005509(calcium ion binding);GO:0007155(cell adhesion);GO:0007156(homophilic cell adhesion via plasma membrane adhesion molecules);GO:0005886(plasma membrane);GO:0005887(integral component of plasma membrane);GO:0070062(extracellular exosome);GO:0007399(nervous system development);GO:0007267(cell-cell signaling);GO:0016339(calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules);GO:0016339(calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules)","NA","NA","NA","protocadherin gamma subfamily C, 3 [Source:HGNC Symbol;Acc:HGNC:8716]",{"v":0.0424561726804124,"d":"0.04"},{"v":0.0185515425257732,"d":"0.02"},{"v":2.28855215793668,"d":"2.29"},{"v":1.19443517248876,"d":"1.19"},1,1,"up","no"]
["ENSG00000268009","SSX4","ENST00000595689","GO:0005634(nucleus);GO:0003676(nucleic acid binding);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0005622(intracellular);GO:0003714(transcription corepressor activity);GO:1903507(negative regulation of nucleic acid-templated transcription)","NA","NA","NA","SSX family member 4 [Source:HGNC Symbol;Acc:HGNC:11338]",0,0,1,0,1,1,"no","no"]
["ENSG00000237265","BX276092.7","ENST00000637198","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000172155","LCE1D","ENST00000326233","GO:0005515(protein binding);GO:0008544(epidermis development);GO:0031424(keratinization);GO:0005198(structural molecule activity);GO:0005737(cytoplasm);GO:0050890(cognition);GO:0018149(peptide cross-linking);GO:0030216(keratinocyte differentiation);GO:0048471(perinuclear region of cytoplasm);GO:0001533(cornified envelope);GO:0071277(cellular response to calcium ion)","NA","NA","NA","late cornified envelope 1D [Source:HGNC Symbol;Acc:HGNC:29465]",0,0,1,0,1,1,"no","no"]
["ENSG00000249042","AC008771.1","ENST00000504300;ENST00000508000","NA","NA","NA","NA",null,{"v":0.283758467089611,"d":"0.28"},{"v":0.305777160983347,"d":"0.31"},{"v":0.927991044776117,"d":"0.93"},{"v":-0.107817211645964,"d":"-0.11"},1,1,"down","no"]
["ENSG00000216817","R3HDM2P2","ENST00000401880","NA","NA","NA","NA","R3H domain containing 2 pseudogene 2 [Source:HGNC Symbol;Acc:HGNC:44057]",0,0,1,0,1,1,"no","no"]
["MSTRG.11760","FLJ20021","ENST00000529296;ENST00000527564","NA","NA","NA","NA","uncharacterized LOC90024 [Source:NCBI gene;Acc:90024]",{"v":0.413238670886076,"d":"0.41"},{"v":1.487692,"d":"1.49"},{"v":0.277771656287777,"d":"0.28"},{"v":-1.84802870010103,"d":"-1.85"},1,1,"down","no"]
["ENSG00000259426","AC027237.3","ENST00000558617","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000260816","AC027279.1","ENST00000568885","NA","NA","NA","NA",null,{"v":0.0124,"d":"0.01"},0,"inf","inf",1,1,"up","no"]
["ENSG00000221844","DPP3P2","ENST00000416030","NA","NA","NA","NA","dipeptidyl peptidase 3 pseudogene 2 [Source:HGNC Symbol;Acc:HGNC:51350]",0,0,1,0,1,1,"no","no"]
["ENSG00000269873","AC245884.10","ENST00000597355","NA","NA","NA","NA",null,0,{"v":0.304029,"d":"0.30"},"-inf","-inf",1,1,"down","no"]
["ENSG00000278607","AC015819.2","ENST00000618730","NA","NA","NA","NA",null,{"v":0.422807,"d":"0.42"},{"v":0.60198,"d":"0.60"},{"v":0.702360543539652,"d":"0.70"},{"v":-0.509716293918622,"d":"-0.51"},1,1,"down","no"]
["ENSG00000139364","TMEM132B","ENST00000299308","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0003674(molecular_function);GO:0008150(biological_process);GO:0005575(cellular_component)","NA","NA","NA","transmembrane protein 132B [Source:HGNC Symbol;Acc:HGNC:29397]",0,0,1,0,1,1,"no","no"]
["ENSG00000147059","SPIN2A","ENST00000374908;ENST00000614076","GO:0005634(nucleus);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0007049(cell cycle);GO:0007276(gamete generation);GO:0051726(regulation of cell cycle);GO:0003674(molecular_function);GO:0005575(cellular_component);GO:0005575(cellular_component)","NA","NA","NA","spindlin family member 2A [Source:HGNC Symbol;Acc:HGNC:20694]",{"v":0.229775156801661,"d":"0.23"},{"v":0.225959925925926,"d":"0.23"},{"v":1.01688454649691,"d":"1.02"},{"v":0.0241558899608425,"d":"0.02"},1,1,"up","no"]
["ENSG00000167281","RBFOX3","ENST00000583458","GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0006397(mRNA processing);GO:0008380(RNA splicing);GO:0005634(nucleus);GO:0043484(regulation of RNA splicing);GO:0005737(cytoplasm);GO:0007399(nervous system development);GO:0003677(DNA binding);GO:0003729(mRNA binding);GO:0000381(regulation of alternative mRNA splicing, via spliceosome);GO:0005622(intracellular);GO:0043025(neuronal cell body);GO:0043204(perikaryon)","NA","NA","NA","RNA binding protein, fox-1 homolog 3 [Source:HGNC Symbol;Acc:HGNC:27097]",0,0,1,0,1,1,"no","no"]
["ENSG00000277718","LINC02255","ENST00000619758","NA","NA","NA","NA","long intergenic non-protein coding RNA 2255 [Source:HGNC Symbol;Acc:HGNC:53153]",{"v":0.218755,"d":"0.22"},0,"inf","inf",1,1,"up","no"]
["ENSG00000234457","AC006960.1","ENST00000419980","NA","NA","NA","NA",null,{"v":0.272155,"d":"0.27"},0,"inf","inf",1,1,"up","no"]
["ENSG00000271133","AC004130.1","ENST00000603156;ENST00000605357","NA","NA","NA","NA",null,{"v":0.0592857276785714,"d":"0.06"},{"v":0.376502744419643,"d":"0.38"},{"v":0.157464264357374,"d":"0.16"},{"v":-2.66690364077697,"d":"-2.67"},1,1,"down","no"]
["ENSG00000242366","UGT1A8","ENST00000373450","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016740(transferase activity);GO:0016757(transferase activity, transferring glycosyl groups);GO:0008152(metabolic process);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0042803(protein homodimerization activity);GO:0016758(transferase activity, transferring hexosyl groups);GO:0043086(negative regulation of catalytic activity);GO:0015020(glucuronosyltransferase activity);GO:0043231(intracellular membrane-bounded organelle);GO:0046982(protein heterodimerization activity);GO:0004857(enzyme inhibitor activity);GO:0001972(retinoic acid binding);GO:0042573(retinoic acid metabolic process);GO:0051552(flavone metabolic process);GO:0052696(flavonoid glucuronidation);GO:0052697(xenobiotic glucuronidation);GO:0045922(negative regulation of fatty acid metabolic process);GO:0005504(fatty acid binding);GO:0008202(steroid metabolic process);GO:0005496(steroid binding);GO:0009804(coumarin metabolic process);GO:0006631(fatty acid metabolic process);GO:0045939(negative regulation of steroid metabolic process)","00040(Pentose and glucuronate interconversions);00053(Ascorbate and aldarate metabolism);00140(Steroid hormone biosynthesis);00830(Retinol metabolism);00860(Porphyrin and chlorophyll metabolism);00980(Metabolism of xenobiotics by cytochrome P450);00982(Drug metabolism - cytochrome P450);00983(Drug metabolism - other enzymes);05204(Chemical carcinogenesis)","K00699","EC:2.4.1.17","UDP glucuronosyltransferase family 1 member A8 [Source:HGNC Symbol;Acc:HGNC:12540]",0,0,1,0,1,1,"no","no"]
["ENSG00000232623","AP000266.1","ENST00000450936","NA","NA","NA","NA",null,{"v":0.164758,"d":"0.16"},0,"inf","inf",1,1,"up","no"]
["ENSG00000168702","LRP1B","ENST00000389484","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005509(calcium ion binding);GO:0006897(endocytosis);GO:0043235(receptor complex);GO:0006898(receptor-mediated endocytosis);GO:0015031(protein transport)","NA","NA","NA","LDL receptor related protein 1B [Source:HGNC Symbol;Acc:HGNC:6693]",0,{"v":0.00298677992957747,"d":"0.00"},"-inf","-inf",1,1,"down","no"]
["ENSG00000164542","KIAA0895","ENST00000317020","NA","NA","NA","NA","KIAA0895 [Source:HGNC Symbol;Acc:HGNC:22206]",{"v":0.0394637404875149,"d":"0.04"},{"v":0.0365937534185493,"d":"0.04"},{"v":1.07842833273044,"d":"1.08"},{"v":0.108930304963964,"d":"0.11"},1,1,"up","no"]
["ENSG00000233903","Z83851.1","ENST00000420096","NA","NA","NA","NA",null,{"v":0.324357,"d":"0.32"},{"v":0.394189,"d":"0.39"},{"v":0.822846401091862,"d":"0.82"},{"v":-0.281304943783866,"d":"-0.28"},1,1,"down","no"]
["MSTRG.4650","RNU2-33P","ENST00000410344","NA","NA","NA","NA","RNA, U2 small nuclear 33, pseudogene [Source:HGNC Symbol;Acc:HGNC:48526]",{"v":0.276666,"d":"0.28"},0,"inf","inf",1,1,"up","no"]
["MSTRG.1847","AC063965.1","ENST00000416679","NA","NA","NA","NA",null,{"v":0.040889,"d":"0.04"},{"v":0.026695,"d":"0.03"},{"v":1.53171005806331,"d":"1.53"},{"v":0.615143231086546,"d":"0.62"},1,1,"up","no"]
["MSTRG.6652","AC138207.8","ENST00000578883;ENST00000582483;ENST00000580190;ENST00000580053;ENST00000579692","NA","NA","NA","NA",null,{"v":0.160556981369353,"d":"0.16"},{"v":0.0917779087098277,"d":"0.09"},{"v":1.74940771288418,"d":"1.75"},{"v":0.806866559589987,"d":"0.81"},1,1,"up","no"]
["MSTRG.4543","AL049780.1","ENST00000554430","NA","NA","NA","NA",null,{"v":0.108629,"d":"0.11"},{"v":0.104073,"d":"0.10"},{"v":1.04377696424625,"d":"1.04"},{"v":0.0618134677010548,"d":"0.06"},1,1,"up","no"]
["ENSG00000157680","DGKI","ENST00000453654;ENST00000424189","GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0005654(nucleoplasm);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0008152(metabolic process);GO:0003951(NAD+ kinase activity);GO:0004143(diacylglycerol kinase activity);GO:0007205(protein kinase C-activating G-protein coupled receptor signaling pathway);GO:0005737(cytoplasm);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0035556(intracellular signal transduction);GO:0005515(protein binding);GO:0005886(plasma membrane);GO:0043234(protein complex);GO:0030168(platelet activation);GO:0034260(negative regulation of GTPase activity);GO:0005095(GTPase inhibitor activity);GO:0017016(Ras GTPase binding);GO:0007269(neurotransmitter secretion);GO:0043087(regulation of GTPase activity);GO:0046579(positive regulation of Ras protein signal transduction);GO:0046834(lipid phosphorylation);GO:0046959(habituation);GO:0051966(regulation of synaptic transmission, glutamatergic);GO:0060079(excitatory postsynaptic potential);GO:1900452(regulation of long term synaptic depression);GO:0005829(cytosol);GO:0008021(synaptic vesicle);GO:0014069(postsynaptic density);GO:0032045(guanyl-nucleotide exchange factor complex);GO:0043025(neuronal cell body);GO:0043197(dendritic spine);GO:0043679(axon terminus);GO:0045202(synapse);GO:0048471(perinuclear region of cytoplasm);GO:0048786(presynaptic active zone);GO:0060076(excitatory synapse);GO:0097060(synaptic membrane);GO:0097060(synaptic membrane)","00561(Glycerolipid metabolism);00564(Glycerophospholipid metabolism);04070(Phosphatidylinositol signaling system);04072(Phospholipase D signaling pathway);05231(Choline metabolism in cancer);05231(Choline metabolism in cancer)","K00901","EC:2.7.1.107","diacylglycerol kinase iota [Source:HGNC Symbol;Acc:HGNC:2855]",{"v":0.00332574442086308,"d":"0.00"},{"v":0.00327336394623448,"d":"0.00"},{"v":1.01600203200407,"d":"1.02"},{"v":0.0229032875030487,"d":"0.02"},1,1,"up","no"]
["ENSG00000264365","AC023983.1","ENST00000579347","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000128917","DLL4","ENST00000557876;ENST00000249749;ENST00000559440","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005509(calcium ion binding);GO:0007275(multicellular organism development);GO:0005886(plasma membrane);GO:0007399(nervous system development);GO:0030154(cell differentiation);GO:0007219(Notch signaling pathway);GO:0007154(cell communication);GO:0050896(response to stimulus);GO:0005515(protein binding);GO:0010628(positive regulation of gene expression);GO:0008285(negative regulation of cell proliferation);GO:0007601(visual perception);GO:2000179(positive regulation of neural precursor cell proliferation);GO:0007165(signal transduction);GO:0010629(negative regulation of gene expression);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0030217(T cell differentiation);GO:0001525(angiogenesis);GO:0010596(negative regulation of endothelial cell migration);GO:0007220(Notch receptor processing);GO:0045747(positive regulation of Notch signaling pathway);GO:0035924(cellular response to vascular endothelial growth factor stimulus);GO:0044344(cellular response to fibroblast growth factor stimulus);GO:0090051(negative regulation of cell migration involved in sprouting angiogenesis);GO:0001569(branching involved in blood vessel morphogenesis);GO:0045746(negative regulation of Notch signaling pathway);GO:0061074(regulation of neural retina development);GO:0008015(blood circulation);GO:0061314(Notch signaling involved in heart development);GO:0001974(blood vessel remodeling);GO:0003208(cardiac ventricle morphogenesis);GO:0003209(cardiac atrium morphogenesis);GO:0003222(ventricular trabecula myocardium morphogenesis);GO:0035912(dorsal aorta morphogenesis);GO:0003344(pericardium morphogenesis);GO:0060579(ventral spinal cord interneuron fate commitment);GO:1903588(negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis);GO:0005112(Notch binding);GO:0043537(negative regulation of blood vessel endothelial cell migration);GO:0050767(regulation of neurogenesis);GO:0072554(blood vessel lumenization);GO:0072554(blood vessel lumenization)","04330(Notch signaling pathway);04658(Th1 and Th2 cell differentiation);05200(Pathways in cancer);05224(Breast cancer);01522(Endocrine resistance);01522(Endocrine resistance)","K06051","NA","delta like canonical Notch ligand 4 [Source:HGNC Symbol;Acc:HGNC:2910]",0,0,1,0,1,1,"no","no"]
["ENSG00000151572","ANO4","ENST00000392979;ENST00000549155","GO:0046983(protein dimerization activity);GO:0061588(calcium activated phospholipid scrambling);GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005886(plasma membrane);GO:0006869(lipid transport);GO:0006821(chloride transport);GO:1902476(chloride transmembrane transport);GO:0005229(intracellular calcium activated chloride channel activity);GO:0034220(ion transmembrane transport);GO:0005622(intracellular);GO:0017128(phospholipid scramblase activity);GO:0061589(calcium activated phosphatidylserine scrambling);GO:0061590(calcium activated phosphatidylcholine scrambling);GO:0061591(calcium activated galactosylceramide scrambling);GO:0061591(calcium activated galactosylceramide scrambling)","NA","NA","NA","anoctamin 4 [Source:HGNC Symbol;Acc:HGNC:23837]",0,0,1,0,1,1,"no","no"]
["ENSG00000184033","CTAG1B","ENST00000359887","GO:0005737(cytoplasm);GO:0005515(protein binding)","NA","NA","NA","cancer/testis antigen 1B [Source:HGNC Symbol;Acc:HGNC:2491]",0,0,1,0,1,1,"no","no"]
["ENSG00000246100","LINC00900","ENST00000501294;ENST00000499809;ENST00000537070;ENST00000514294;ENST00000535683","NA","NA","NA","NA","long intergenic non-protein coding RNA 900 [Source:HGNC Symbol;Acc:HGNC:27444]",{"v":0.0737352519932858,"d":"0.07"},{"v":0.0426416269408309,"d":"0.04"},{"v":1.72918477279491,"d":"1.73"},{"v":0.790092037026536,"d":"0.79"},1,1,"up","no"]
["ENSG00000259514","AC027243.1","ENST00000559539","NA","NA","NA","NA",null,{"v":0.08457,"d":"0.08"},{"v":0.245567,"d":"0.25"},{"v":0.344386664331934,"d":"0.34"},{"v":-1.53789881648095,"d":"-1.54"},1,1,"down","no"]
["ENSG00000260267","AC026471.1","ENST00000564629","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000229212","AC044860.1","ENST00000560405;ENST00000558470;ENST00000559481;ENST00000560756;ENST00000560811","NA","NA","NA","NA",null,{"v":0.256419470230863,"d":"0.26"},{"v":0.123871696840826,"d":"0.12"},{"v":2.07004083071825,"d":"2.07"},{"v":1.0496592245815,"d":"1.05"},1,1,"up","no"]
["ENSG00000259414","AC242376.1","ENST00000559033","NA","NA","NA","NA",null,{"v":1.333E-3,"d":"0.00"},{"v":0.01691,"d":"0.02"},{"v":0.0788290952099349,"d":"0.08"},{"v":-3.66512797420837,"d":"-3.67"},1,1,"down","no"]
["ENSG00000272760","AC093726.1","ENST00000608064","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000248874","C5orf17","ENST00000512559","NA","NA","NA","NA","chromosome 5 open reading frame 17 [Source:HGNC Symbol;Acc:HGNC:26630]",{"v":0.053548,"d":"0.05"},{"v":0.038477,"d":"0.04"},{"v":1.39168854120644,"d":"1.39"},{"v":0.476836373302919,"d":"0.48"},1,1,"up","no"]
["ENSG00000188064","WNT7B","ENST00000339464","GO:0005102(receptor binding);GO:0005576(extracellular region);GO:0007275(multicellular organism development);GO:0016055(Wnt signaling pathway);GO:0005578(proteinaceous extracellular matrix);GO:0005615(extracellular space);GO:0005886(plasma membrane);GO:0005788(endoplasmic reticulum lumen);GO:0030666(endocytic vesicle membrane);GO:0050808(synapse organization);GO:0005796(Golgi lumen);GO:0042592(homeostatic process);GO:0005109(frizzled binding);GO:0030182(neuron differentiation);GO:0045165(cell fate commitment);GO:0071300(cellular response to retinoic acid);GO:0070307(lens fiber cell development);GO:0070062(extracellular exosome);GO:0001701(in utero embryonic development);GO:0060070(canonical Wnt signaling pathway);GO:0060425(lung morphogenesis);GO:0045669(positive regulation of osteoblast differentiation);GO:0061180(mammary gland epithelium development);GO:0030324(lung development);GO:0072205(metanephric collecting duct development);GO:0072207(metanephric epithelium development);GO:0072236(metanephric loop of Henle development);GO:0048568(embryonic organ development);GO:0032364(oxygen homeostasis);GO:0072089(stem cell proliferation);GO:0021871(forebrain regionalization);GO:0003338(metanephros morphogenesis);GO:0007257(activation of JUN kinase activity);GO:0016332(establishment or maintenance of polarity of embryonic epithelium);GO:0022009(central nervous system vasculogenesis);GO:0031175(neuron projection development);GO:0032536(regulation of cell projection size);GO:0044237(cellular metabolic process);GO:0046330(positive regulation of JNK cascade);GO:0048144(fibroblast proliferation);GO:0048812(neuron projection morphogenesis);GO:0051384(response to glucocorticoid);GO:0060428(lung epithelium development);GO:0060482(lobar bronchus development);GO:0060535(trachea cartilage morphogenesis);GO:0060560(developmental growth involved in morphogenesis);GO:0060669(embryonic placenta morphogenesis);GO:0060710(chorio-allantoic fusion);GO:0072053(renal inner medulla development);GO:0072054(renal outer medulla development);GO:0072060(outer medullary collecting duct development);GO:0072061(inner medullary collecting duct development);GO:0005737(cytoplasm)","04310(Wnt signaling pathway);04390(Hippo signaling pathway);04150(mTOR signaling pathway);04550(Signaling pathways regulating pluripotency of stem cells);04916(Melanogenesis);05200(Pathways in cancer);05205(Proteoglycans in cancer);05225(Hepatocellular carcinoma);05226(Gastric cancer);05217(Basal cell carcinoma);05224(Breast cancer);05166(HTLV-I infection);05165(Human papillomavirus infection)","K00572","NA","Wnt family member 7B [Source:HGNC Symbol;Acc:HGNC:12787]",{"v":0.0104814434765393,"d":"0.01"},0,"inf","inf",1,1,"up","no"]
["ENSG00000189326","SPANXN4","ENST00000446864","NA","NA","NA","NA","SPANX family member N4 [Source:HGNC Symbol;Acc:HGNC:33177]",{"v":0.0405257232,"d":"0.04"},0,"inf","inf",1,1,"up","no"]
["ENSG00000236403","AL353611.1","ENST00000417054","NA","NA","NA","NA",null,0,{"v":0.178364,"d":"0.18"},"-inf","-inf",1,1,"down","no"]
["ENSG00000069482","GAL","ENST00000265643","GO:0005576(extracellular region);GO:0005515(protein binding);GO:0005615(extracellular space);GO:0005179(hormone activity);GO:0007218(neuropeptide signaling pathway);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0030141(secretory granule);GO:0005184(neuropeptide hormone activity);GO:0019933(cAMP-mediated signaling);GO:0004966(galanin receptor activity);GO:1902608(positive regulation of large conductance calcium-activated potassium channel activity);GO:0043025(neuronal cell body);GO:0010737(protein kinase A signaling);GO:0030073(insulin secretion);GO:0031764(type 1 galanin receptor binding);GO:0031765(type 2 galanin receptor binding);GO:0031766(type 3 galanin receptor binding);GO:0006954(inflammatory response);GO:0007399(nervous system development);GO:0007631(feeding behavior);GO:0008285(negative regulation of cell proliferation);GO:0031943(regulation of glucocorticoid metabolic process);GO:0032868(response to insulin);GO:0035902(response to immobilization stress);GO:0042493(response to drug);GO:0043065(positive regulation of apoptotic process);GO:0043627(response to estrogen);GO:0050672(negative regulation of lymphocyte proliferation);GO:0051464(positive regulation of cortisol secretion);GO:0051795(positive regulation of timing of catagen);GO:1902891(negative regulation of root hair elongation);GO:0005737(cytoplasm);GO:0005794(Golgi apparatus)","04080(Neuroactive ligand-receptor interaction)","K05244","NA","galanin and GMAP prepropeptide [Source:HGNC Symbol;Acc:HGNC:4114]",0,0,1,0,1,1,"no","no"]
["ENSG00000268803","AC114797.1","ENST00000514003","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000121853","GHSR","ENST00000427970","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0004930(G-protein coupled receptor activity);GO:0007186(G-protein coupled receptor signaling pathway);GO:0005886(plasma membrane);GO:0008154(actin polymerization or depolymerization);GO:0004871(signal transducer activity);GO:0007165(signal transduction);GO:0045121(membrane raft);GO:0009986(cell surface);GO:0050728(negative regulation of inflammatory response);GO:0043005(neuron projection);GO:0016520(growth hormone-releasing hormone receptor activity);GO:0008343(adult feeding behavior);GO:0032100(positive regulation of appetite);GO:0009725(response to hormone);GO:0046697(decidualization);GO:0042536(negative regulation of tumor necrosis factor biosynthetic process);GO:0001616(growth hormone secretagogue receptor activity);GO:0017046(peptide hormone binding);GO:0042562(hormone binding);GO:0007283(spermatogenesis);GO:0007565(female pregnancy);GO:0007611(learning or memory);GO:0009755(hormone-mediated signaling pathway);GO:0010700(negative regulation of norepinephrine secretion);GO:0030252(growth hormone secretion);GO:0032094(response to food);GO:0032099(negative regulation of appetite);GO:0032354(response to follicle-stimulating hormone);GO:0032355(response to estradiol);GO:0032691(negative regulation of interleukin-1 beta production);GO:0032869(cellular response to insulin stimulus);GO:0036321(ghrelin secretion);GO:0040018(positive regulation of multicellular organism growth);GO:0043134(regulation of hindgut contraction);GO:0043568(positive regulation of insulin-like growth factor receptor signaling pathway);GO:0045409(negative regulation of interleukin-6 biosynthetic process);GO:0045923(positive regulation of fatty acid metabolic process);GO:0045927(positive regulation of growth);GO:0046676(negative regulation of insulin secretion);GO:0051963(regulation of synapse assembly);GO:0051969(regulation of transmission of nerve impulse);GO:0060123(regulation of growth hormone secretion);GO:0060259(regulation of feeding behavior);GO:0060416(response to growth hormone);GO:0071222(cellular response to lipopolysaccharide);GO:0071548(response to dexamethasone);GO:0090327(negative regulation of locomotion involved in locomotory behavior);GO:0097067(cellular response to thyroid hormone stimulus);GO:0120058(-);GO:1903672(positive regulation of sprouting angiogenesis);GO:1904000(positive regulation of eating behavior);GO:1904008(response to monosodium glutamate);GO:1904349(positive regulation of small intestine smooth muscle contraction);GO:1904468(negative regulation of tumor necrosis factor secretion);GO:1905333(regulation of gastric motility);GO:1905564(positive regulation of vascular endothelial cell proliferation);GO:1990314(cellular response to insulin-like growth factor stimulus);GO:2000110(negative regulation of macrophage apoptotic process)","04024(cAMP signaling pathway);04080(Neuroactive ligand-receptor interaction)","K04284","NA","growth hormone secretagogue receptor [Source:HGNC Symbol;Acc:HGNC:4267]",0,0,1,0,1,1,"no","no"]
["ENSG00000230400","LINC01747","ENST00000441568","NA","NA","NA","NA","long intergenic non-protein coding RNA 1747 [Source:HGNC Symbol;Acc:HGNC:52536]",0,{"v":0.0117099677864703,"d":"0.01"},"-inf","-inf",1,1,"down","no"]
["MSTRG.7901","AC008569.1","ENST00000590626","NA","NA","NA","NA",null,{"v":0.598564,"d":"0.60"},{"v":0.006018,"d":"0.01"},{"v":99.4622798271851,"d":"99.46"},{"v":6.63607759517823,"d":"6.64"},1,1,"up","no"]
["MSTRG.8251","DACT3-AS1","ENST00000500689;ENST00000525008","NA","NA","NA","NA","DACT3 antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:44120]",{"v":0.0480185687671233,"d":"0.05"},{"v":0.0260173063013699,"d":"0.03"},{"v":1.84563952205133,"d":"1.85"},{"v":0.884120802965871,"d":"0.88"},1,1,"up","no"]
["ENSG00000227264","ACTR3BP5","ENST00000448440","NA","NA","NA","NA","ACTR3B pseudogene 5 [Source:HGNC Symbol;Acc:HGNC:38682]",0,0,1,0,1,1,"no","no"]
["ENSG00000251359","WWC2-AS2","ENST00000578387","NA","NA","NA","NA","WWC2 antisense RNA 2 [Source:HGNC Symbol;Acc:HGNC:26390]",0,0,1,0,1,1,"no","no"]
["ENSG00000196406","SPANXD","ENST00000370515","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005515(protein binding)","NA","NA","NA","SPANX family member D [Source:HGNC Symbol;Acc:HGNC:14332]",0,0,1,0,1,1,"no","no"]
["ENSG00000146221","TCTE1","ENST00000371505","NA","NA","NA","NA","t-complex-associated-testis-expressed 1 [Source:HGNC Symbol;Acc:HGNC:11693]",0,{"v":0.033187,"d":"0.03"},"-inf","-inf",1,1,"down","no"]
["MSTRG.6432","MYH10","ENST00000360416;ENST00000488329;ENST00000476737;ENST00000469865","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0003774(motor activity);GO:0051015(actin filament binding);GO:0016459(myosin complex);GO:0007155(cell adhesion);GO:0003779(actin binding);GO:0042995(cell projection);GO:0030496(midbody);GO:0005516(calmodulin binding);GO:0005515(protein binding);GO:0005829(cytosol);GO:0030027(lamellipodium);GO:0070062(extracellular exosome);GO:0001725(stress fiber);GO:0005938(cell cortex);GO:0032154(cleavage furrow);GO:0016887(ATPase activity);GO:0008360(regulation of cell shape);GO:0030898(actin-dependent ATPase activity);GO:0000281(mitotic cytokinesis);GO:0000146(microfilament motor activity);GO:0043531(ADP binding);GO:0030048(actin filament-based movement);GO:0031032(actomyosin structure organization);GO:0016460(myosin II complex);GO:0042641(actomyosin);GO:0097513(myosin II filament);GO:0097513(myosin II filament)","04530(Tight junction);04810(Regulation of actin cytoskeleton);05132(Salmonella infection);05132(Salmonella infection)","K10352","NA","myosin heavy chain 10 [Source:HGNC Symbol;Acc:HGNC:7568]",{"v":0.441177221396071,"d":"0.44"},{"v":0.0681179889024526,"d":"0.07"},{"v":6.47666245737015,"d":"6.48"},{"v":2.69525055745696,"d":"2.70"},1,1,"up","no"]
["ENSG00000187135","VSTM2B","ENST00000335523","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005886(plasma membrane)","NA","NA","NA","V-set and transmembrane domain containing 2B [Source:HGNC Symbol;Acc:HGNC:33595]",{"v":0.511958,"d":"0.51"},{"v":0.102604,"d":"0.10"},{"v":4.98964952633426,"d":"4.99"},{"v":2.31893848402411,"d":"2.32"},1,1,"up","no"]
["MSTRG.7559","AC018445.3","ENST00000624177","NA","NA","NA","NA",null,{"v":0.027311,"d":"0.03"},0,"inf","inf",1,1,"up","no"]
["ENSG00000269300","AC008734.1","ENST00000594006","NA","NA","NA","NA",null,{"v":0.071846,"d":"0.07"},{"v":0.093515,"d":"0.09"},{"v":0.76828316312891,"d":"0.77"},{"v":-0.380289957444005,"d":"-0.38"},1,1,"down","no"]
["MSTRG.13435","GPR146","ENST00000481403;ENST00000427680;ENST00000474396;ENST00000444847;ENST00000397095","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0004930(G-protein coupled receptor activity);GO:0007186(G-protein coupled receptor signaling pathway);GO:0005886(plasma membrane);GO:0004871(signal transducer activity);GO:0007165(signal transduction);GO:0007165(signal transduction)","NA","NA","NA","G protein-coupled receptor 146 [Source:HGNC Symbol;Acc:HGNC:21718]",{"v":0.0661917816455696,"d":"0.07"},{"v":1.04943772848101,"d":"1.05"},{"v":0.0630735677298144,"d":"0.06"},{"v":-3.98682064881976,"d":"-3.99"},1,1,"down","no"]
["ENSG00000271736","AL138900.3","ENST00000607010","NA","NA","NA","NA",null,{"v":0.119686,"d":"0.12"},{"v":0.065102,"d":"0.07"},{"v":1.83843814322141,"d":"1.84"},{"v":0.878480635899918,"d":"0.88"},1,1,"up","no"]
["ENSG00000172554","SNTG2","ENST00000489646;ENST00000452177;ENST00000308624","GO:0005198(structural molecule activity);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0003779(actin binding);GO:0005886(plasma membrane);GO:0005856(cytoskeleton);GO:0042383(sarcolemma);GO:0007417(central nervous system development);GO:0030165(PDZ domain binding);GO:0097109(neuroligin family protein binding);GO:0016013(syntrophin complex);GO:0016013(syntrophin complex)","NA","NA","NA","syntrophin gamma 2 [Source:HGNC Symbol;Acc:HGNC:13741]",{"v":0.0294399570373685,"d":"0.03"},{"v":0.011387620049228,"d":"0.01"},{"v":2.5852598620345,"d":"2.59"},{"v":1.37030930291,"d":"1.37"},1,1,"up","no"]
["ENSG00000162878","PKDCC","ENST00000490302;ENST00000294964;ENST00000475241","GO:0006810(transport);GO:0015031(protein transport);GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0005794(Golgi apparatus);GO:0004713(protein tyrosine kinase activity);GO:0005576(extracellular region);GO:0004715(non-membrane spanning protein tyrosine kinase activity);GO:0007275(multicellular organism development);GO:0030154(cell differentiation);GO:0001503(ossification);GO:0030501(positive regulation of bone mineralization);GO:0032332(positive regulation of chondrocyte differentiation);GO:0060021(palate development);GO:0048286(lung alveolus development);GO:0018108(peptidyl-tyrosine phosphorylation);GO:0048566(embryonic digestive tract development);GO:0042997(negative regulation of Golgi to plasma membrane protein transport);GO:0001501(skeletal system development);GO:0030282(bone mineralization);GO:0035108(limb morphogenesis);GO:0035264(multicellular organism growth);GO:0035264(multicellular organism growth)","NA","NA","NA","protein kinase domain containing, cytoplasmic [Source:HGNC Symbol;Acc:HGNC:25123]",{"v":0.0521837518471338,"d":"0.05"},{"v":0.0415818086624204,"d":"0.04"},{"v":1.25496589796718,"d":"1.25"},{"v":0.32764816138554,"d":"0.33"},1,1,"up","no"]
["ENSG00000203690","TCP10","ENST00000617120","GO:0005829(cytosol)","NA","NA","NA","t-complex 10 [Source:HGNC Symbol;Acc:HGNC:11656]",0,0,1,0,1,1,"no","no"]
["ENSG00000249601","LINC01187","ENST00000506431","NA","NA","NA","NA","long intergenic non-protein coding RNA 1187 [Source:HGNC Symbol;Acc:HGNC:49575]",{"v":0.034616,"d":"0.03"},0,"inf","inf",1,1,"up","no"]
["ENSG00000141750","STAC2","ENST00000333461","GO:0005622(intracellular);GO:0046872(metal ion binding);GO:0035556(intracellular signal transduction);GO:0005515(protein binding)","NA","NA","NA","SH3 and cysteine rich domain 2 [Source:HGNC Symbol;Acc:HGNC:23990]",{"v":0.031548,"d":"0.03"},0,"inf","inf",1,1,"up","no"]
["MSTRG.6929","AC091132.2","ENST00000433601","NA","NA","NA","NA",null,{"v":0.219945,"d":"0.22"},0,"inf","inf",1,1,"up","no"]
["MSTRG.7851","FARSA-AS1","ENST00000592636","NA","NA","NA","NA","FARSA antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:50479]",0,0,1,0,1,1,"no","no"]
["ENSG00000260194","AC007496.1","ENST00000565641","NA","NA","NA","NA",null,{"v":0.060149,"d":"0.06"},0,"inf","inf",1,1,"up","no"]
["MSTRG.15496","MIR3202-2","ENST00000635980","NA","NA","NA","NA","microRNA 3202-2 [Source:HGNC Symbol;Acc:HGNC:38228]",0,{"v":0.021331,"d":"0.02"},"-inf","-inf",1,1,"down","no"]
["ENSG00000243959","RN7SL684P","ENST00000465665","NA","NA","NA","NA","RNA, 7SL, cytoplasmic 684, pseudogene [Source:HGNC Symbol;Acc:HGNC:46700]",{"v":0.18068,"d":"0.18"},0,"inf","inf",1,1,"up","no"]
["MSTRG.14482","AC104986.1","ENST00000517978","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000179859","AC104581.1","ENST00000324348;ENST00000640240;ENST00000635932","GO:0046872(metal ion binding);GO:0046872(metal ion binding)","NA","NA","NA",null,{"v":0.0461034933965459,"d":"0.05"},{"v":0.222928661022689,"d":"0.22"},{"v":0.206808282008448,"d":"0.21"},{"v":-2.27363413276805,"d":"-2.27"},1,1,"down","no"]
["ENSG00000121053","EPX","ENST00000225371","GO:0046872(metal ion binding);GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0020037(heme binding);GO:0098869(cellular oxidant detoxification);GO:0006952(defense response);GO:0005615(extracellular space);GO:0005576(extracellular region);GO:0004601(peroxidase activity);GO:0006979(response to oxidative stress);GO:0070062(extracellular exosome);GO:0042744(hydrogen peroxide catabolic process);GO:0043312(neutrophil degranulation);GO:0034774(secretory granule lumen);GO:0002215(defense response to nematode);GO:0032693(negative regulation of interleukin-10 production);GO:0032714(negative regulation of interleukin-5 production);GO:0032753(positive regulation of interleukin-4 production);GO:0072677(eosinophil migration)","05310(Asthma)","K10788","EC:1.11.1.7","eosinophil peroxidase [Source:HGNC Symbol;Acc:HGNC:3423]",{"v":0.121802,"d":"0.12"},{"v":0.029997,"d":"0.03"},{"v":4.06047271393806,"d":"4.06"},{"v":2.02164769350775,"d":"2.02"},1,1,"up","no"]
["ENSG00000100078","PLA2G3","ENST00000215885","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0046872(metal ion binding);GO:0016787(hydrolase activity);GO:0006629(lipid metabolic process);GO:0016042(lipid catabolic process);GO:0005886(plasma membrane);GO:0005856(cytoskeleton);GO:0005576(extracellular region);GO:0004623(phospholipase A2 activity);GO:0006644(phospholipid metabolic process);GO:0050482(arachidonic acid secretion);GO:0042629(mast cell granule);GO:0060271(cilium assembly);GO:0030030(cell projection organization);GO:0005814(centriole);GO:0005615(extracellular space);GO:0036148(phosphatidylglycerol acyl-chain remodeling);GO:0036151(phosphatidylcholine acyl-chain remodeling);GO:0036152(phosphatidylethanolamine acyl-chain remodeling);GO:0047498(calcium-dependent phospholipase A2 activity);GO:0001675(acrosome assembly);GO:0007288(sperm axoneme assembly);GO:0019372(lipoxygenase pathway);GO:0043303(mast cell degranulation);GO:0046470(phosphatidylcholine metabolic process);GO:0048468(cell development)","00564(Glycerophospholipid metabolism);00565(Ether lipid metabolism);00590(Arachidonic acid metabolism);00591(Linoleic acid metabolism);00592(alpha-Linolenic acid metabolism);04014(Ras signaling pathway);04270(Vascular smooth muscle contraction);04972(Pancreatic secretion);04975(Fat digestion and absorption)","K01047","EC:3.1.1.4","phospholipase A2 group III [Source:HGNC Symbol;Acc:HGNC:17934]",0,0,1,0,1,1,"no","no"]
["MSTRG.14454","PLEKHF2","ENST00000519516;ENST00000315367","GO:0006810(transport);GO:0016020(membrane);GO:0015031(protein transport);GO:0046872(metal ion binding);GO:0005783(endoplasmic reticulum);GO:0005515(protein binding);GO:0005768(endosome);GO:0031901(early endosome membrane);GO:0030133(transport vesicle);GO:0030133(transport vesicle)","NA","NA","NA","pleckstrin homology and FYVE domain containing 2 [Source:HGNC Symbol;Acc:HGNC:20757]",0,{"v":1.78693018807778e-05,"d":"0.00"},"-inf","-inf",1,1,"down","no"]
["ENSG00000158806","NPM2","ENST00000522953;ENST00000397940","GO:0005634(nucleus);GO:0016569(covalent chromatin modification);GO:0000790(nuclear chromatin);GO:0005515(protein binding);GO:0007275(multicellular organism development);GO:0007338(single fertilization);GO:0042393(histone binding);GO:0006338(chromatin remodeling);GO:0009790(embryo development);GO:0007096(regulation of exit from mitosis);GO:0009994(oocyte differentiation);GO:0045836(positive regulation of meiotic nuclear division);GO:0000789(cytoplasmic chromatin);GO:0003682(chromatin binding);GO:0019899(enzyme binding);GO:0043085(positive regulation of catalytic activity);GO:0045740(positive regulation of DNA replication);GO:0051054(positive regulation of DNA metabolic process);GO:0051260(protein homooligomerization);GO:0051260(protein homooligomerization)","NA","NA","NA","nucleophosmin/nucleoplasmin 2 [Source:HGNC Symbol;Acc:HGNC:7930]",0,{"v":0.0492560693165293,"d":"0.05"},"-inf","-inf",1,1,"down","no"]
["MSTRG.10684","FGD5","ENST00000640506;ENST00000285046;ENST00000543601","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0046872(metal ion binding);GO:0005794(Golgi apparatus);GO:0005783(endoplasmic reticulum);GO:0005886(plasma membrane);GO:0005089(Rho guanyl-nucleotide exchange factor activity);GO:0035023(regulation of Rho protein signal transduction);GO:0043547(positive regulation of GTPase activity);GO:0005856(cytoskeleton);GO:0042995(cell projection);GO:0005515(protein binding);GO:0005085(guanyl-nucleotide exchange factor activity);GO:0005768(endosome);GO:0030027(lamellipodium);GO:0032587(ruffle membrane);GO:0005769(early endosome);GO:0007010(cytoskeleton organization);GO:0008360(regulation of cell shape);GO:0001726(ruffle);GO:0030036(actin cytoskeleton organization);GO:0043087(regulation of GTPase activity);GO:0046847(filopodium assembly);GO:0031267(small GTPase binding);GO:0031267(small GTPase binding)","NA","NA","NA","FYVE, RhoGEF and PH domain containing 5 [Source:HGNC Symbol;Acc:HGNC:19117]",{"v":0.00656338959594711,"d":"0.01"},{"v":0.0125352259977759,"d":"0.01"},{"v":0.523595633386397,"d":"0.52"},{"v":-0.933475029151303,"d":"-0.93"},1,1,"down","no"]
["MSTRG.3843","ABCB9","ENST00000442028;ENST00000538895;ENST00000542678;ENST00000545373;ENST00000536976;ENST00000537276;ENST00000546289;ENST00000280560","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0015031(protein transport);GO:0043231(intracellular membrane-bounded organelle);GO:0055085(transmembrane transport);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0005765(lysosomal membrane);GO:0042803(protein homodimerization activity);GO:0042626(ATPase activity, coupled to transmembrane movement of substances);GO:0016887(ATPase activity);GO:0005764(lysosome);GO:0015440(peptide-transporting ATPase activity);GO:0015833(peptide transport);GO:0005515(protein binding);GO:0035672(oligopeptide transmembrane transport);GO:0030176(integral component of endoplasmic reticulum membrane);GO:0015421(oligopeptide-transporting ATPase activity);GO:0022891(substrate-specific transmembrane transporter activity);GO:0022891(substrate-specific transmembrane transporter activity)","02010(ABC transporters);04142(Lysosome);04142(Lysosome)","K05656","NA","ATP binding cassette subfamily B member 9 [Source:HGNC Symbol;Acc:HGNC:50]",{"v":0.090910863140471,"d":"0.09"},{"v":0.0554454227672861,"d":"0.06"},{"v":1.63964595458203,"d":"1.64"},{"v":0.713384330263735,"d":"0.71"},1,1,"up","no"]
["ENSG00000240890","AC020633.1","ENST00000468439","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000144644","GADL1","ENST00000454381;ENST00000282538","GO:0003824(catalytic activity);GO:0016829(lyase activity);GO:0016831(carboxy-lyase activity);GO:0030170(pyridoxal phosphate binding);GO:0019752(carboxylic acid metabolic process);GO:0005829(cytosol);GO:0008652(cellular amino acid biosynthetic process);GO:0004068(aspartate 1-decarboxylase activity);GO:0004782(sulfinoalanine decarboxylase activity);GO:0004782(sulfinoalanine decarboxylase activity)","00410(beta-Alanine metabolism);00430(Taurine and hypotaurine metabolism);00770(Pantothenate and CoA biosynthesis);00770(Pantothenate and CoA biosynthesis)","K18966","EC:4.1.1.29;EC:4.1.1.11","glutamate decarboxylase like 1 [Source:HGNC Symbol;Acc:HGNC:27949]",0,0,1,0,1,1,"no","no"]
["ENSG00000256185","AC055720.2","ENST00000537724","NA","NA","NA","NA",null,{"v":2.755988,"d":"2.76"},{"v":1.763057,"d":"1.76"},{"v":1.56318712327508,"d":"1.56"},{"v":0.64449048829426,"d":"0.64"},1,1,"up","no"]
["ENSG00000283288","AC138517.2","ENST00000637503","GO:0016020(membrane);GO:0016021(integral component of membrane)","NA","NA","NA",null,{"v":0.020478,"d":"0.02"},{"v":0.078476,"d":"0.08"},{"v":0.260946021713645,"d":"0.26"},{"v":-1.93817668755528,"d":"-1.94"},1,1,"down","no"]
["MSTRG.14749","AL162231.2","ENST00000434627","NA","NA","NA","NA",null,{"v":0.431358,"d":"0.43"},{"v":0.349128,"d":"0.35"},{"v":1.23552966247336,"d":"1.24"},{"v":0.305129647161655,"d":"0.31"},1,1,"up","no"]
["ENSG00000272844","AC074044.1","ENST00000609673","NA","NA","NA","NA",null,{"v":0.075134,"d":"0.08"},{"v":0.071983,"d":"0.07"},{"v":1.04377422446967,"d":"1.04"},{"v":0.0618096808122714,"d":"0.06"},1,1,"up","no"]
["ENSG00000136542","GALNT5","ENST00000259056","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0046872(metal ion binding);GO:0016740(transferase activity);GO:0030246(carbohydrate binding);GO:0016757(transferase activity, transferring glycosyl groups);GO:0005794(Golgi apparatus);GO:0000139(Golgi membrane);GO:0006486(protein glycosylation);GO:0005575(cellular_component);GO:0016266(O-glycan processing);GO:0006024(glycosaminoglycan biosynthetic process);GO:0004653(polypeptide N-acetylgalactosaminyltransferase activity)","00512(Mucin type O-glycan biosynthesis)","K00710","EC:2.4.1.41","polypeptide N-acetylgalactosaminyltransferase 5 [Source:HGNC Symbol;Acc:HGNC:4127]",{"v":0.00779113640363743,"d":"0.01"},{"v":0.0223931814315048,"d":"0.02"},{"v":0.347924497797179,"d":"0.35"},{"v":-1.52315383039864,"d":"-1.52"},1,1,"down","no"]
["ENSG00000259838","ELOCP2","ENST00000566760","NA","NA","NA","NA","elongin C pseudogene 2 [Source:HGNC Symbol;Acc:HGNC:17762]",{"v":0.106077,"d":"0.11"},0,"inf","inf",1,1,"up","no"]
["MSTRG.12194","HSPD1P11","ENST00000508643","NA","NA","NA","NA","heat shock protein family D (Hsp60) member 1 pseudogene 11 [Source:HGNC Symbol;Acc:HGNC:35142]",0,0,1,0,1,1,"no","no"]
["ENSG00000137877","SPTBN5","ENST00000320955","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0003779(actin binding);GO:0051693(actin filament capping);GO:0043547(positive regulation of GTPase activity);GO:0005856(cytoskeleton);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0000165(MAPK cascade);GO:0007411(axon guidance);GO:0006888(ER to Golgi vesicle-mediated transport);GO:0005088(Ras guanyl-nucleotide exchange factor activity);GO:0030036(actin cytoskeleton organization);GO:0030507(spectrin binding);GO:0051260(protein homooligomerization);GO:0008091(spectrin);GO:0032391(photoreceptor connecting cilium);GO:0007041(lysosomal transport);GO:0043621(protein self-association);GO:0007030(Golgi organization);GO:0019894(kinesin binding);GO:0032029(myosin tail binding);GO:0034452(dynactin binding);GO:0045505(dynein intermediate chain binding);GO:0097381(photoreceptor disc membrane)","NA","NA","NA","spectrin beta, non-erythrocytic 5 [Source:HGNC Symbol;Acc:HGNC:15680]",{"v":0.18046692737883,"d":"0.18"},{"v":0.0548455928837737,"d":"0.05"},{"v":3.29045449032281,"d":"3.29"},{"v":1.71828686835246,"d":"1.72"},1,1,"up","no"]
["ENSG00000225489","AL354707.1","ENST00000615168;ENST00000443688","NA","NA","NA","NA",null,{"v":0.0374216629094752,"d":"0.04"},{"v":0.0179262648820007,"d":"0.02"},{"v":2.08753263191203,"d":"2.09"},{"v":1.06179874969673,"d":"1.06"},1,1,"up","no"]
["ENSG00000247516","MIR4458HG","ENST00000502001;ENST00000606459;ENST00000605918","NA","NA","NA","NA","MIR4458 host gene [Source:HGNC Symbol;Acc:HGNC:49008]",{"v":0.0263370587693017,"d":"0.03"},{"v":0.0523287727587002,"d":"0.05"},{"v":0.503299759976177,"d":"0.50"},{"v":-0.99051018507413,"d":"-0.99"},1,1,"down","no"]
["MSTRG.2330","AC087276.3","ENST00000526220","NA","NA","NA","NA",null,0,{"v":0.120605,"d":"0.12"},"-inf","-inf",1,1,"down","no"]
["ENSG00000119411","BSPRY","ENST00000374183","GO:0006810(transport);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0046872(metal ion binding);GO:0006811(ion transport);GO:0006816(calcium ion transport);GO:1990830(cellular response to leukemia inhibitory factor);GO:0031252(cell leading edge);GO:0048471(perinuclear region of cytoplasm)","NA","NA","NA","B-box and SPRY domain containing [Source:HGNC Symbol;Acc:HGNC:18232]",{"v":0.226879,"d":"0.23"},{"v":0.192291,"d":"0.19"},{"v":1.17987321299489,"d":"1.18"},{"v":0.238631838560823,"d":"0.24"},1,1,"up","no"]
["ENSG00000168004","HRASLS5","ENST00000540857","GO:0016740(transferase activity);GO:0016746(transferase activity, transferring acyl groups);GO:0016410(N-acyltransferase activity);GO:0070292(N-acylphosphatidylethanolamine metabolic process)","NA","NA","NA","HRAS like suppressor family member 5 [Source:HGNC Symbol;Acc:HGNC:24978]",{"v":0.0975268592411261,"d":"0.10"},{"v":0.123860168910649,"d":"0.12"},{"v":0.787394850974897,"d":"0.79"},{"v":-0.344840816600809,"d":"-0.34"},1,1,"down","no"]
["ENSG00000204361","NXPE2","ENST00000389586","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005515(protein binding)","NA","NA","NA","neurexophilin and PC-esterase domain family member 2 [Source:HGNC Symbol;Acc:HGNC:26331]",0,0,1,0,1,1,"no","no"]
["ENSG00000264924","AC090772.1","ENST00000583782","NA","NA","NA","NA",null,0,{"v":0.30739,"d":"0.31"},"-inf","-inf",1,1,"down","no"]
["MSTRG.10564","AL031595.2","ENST00000624215","NA","NA","NA","NA",null,0,{"v":0.005337,"d":"0.01"},"-inf","-inf",1,1,"down","no"]
["ENSG00000267943","AC010328.1","ENST00000596769","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000225408","AL136980.1","ENST00000426764","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000104833","TUBB4A","ENST00000594290;ENST00000264071;ENST00000601152;ENST00000597686;ENST00000596291","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005525(GTP binding);GO:0000166(nucleotide binding);GO:0003924(GTPase activity);GO:0015630(microtubule cytoskeleton);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0005200(structural constituent of cytoskeleton);GO:0007010(cytoskeleton organization);GO:0005874(microtubule);GO:0007017(microtubule-based process);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0000086(G2/M transition of mitotic cell cycle);GO:0010389(regulation of G2/M transition of mitotic cell cycle);GO:0097711(ciliary basal body docking);GO:0005509(calcium ion binding);GO:0031115(negative regulation of microtubule polymerization);GO:0005929(cilium);GO:0033269(internode region of axon);GO:0042995(cell projection);GO:0043025(neuronal cell body);GO:0043209(myelin sheath);GO:0043209(myelin sheath)","04145(Phagosome);04540(Gap junction);05130(Pathogenic Escherichia coli infection);05130(Pathogenic Escherichia coli infection)","K07375","NA","tubulin beta 4A class IVa [Source:HGNC Symbol;Acc:HGNC:20774]",{"v":0.371665240046163,"d":"0.37"},{"v":0.175565966532025,"d":"0.18"},{"v":2.11695493943223,"d":"2.12"},{"v":1.08199056110293,"d":"1.08"},1,1,"up","no"]
["ENSG00000140104","C14orf79","ENST00000549584;ENST00000550614;ENST00000547315;ENST00000549240","NA","NA","NA","NA","chromosome 14 open reading frame 79 [Source:HGNC Symbol;Acc:HGNC:20126]",{"v":0.115114458181818,"d":"0.12"},{"v":0.0927775898564593,"d":"0.09"},{"v":1.24075715223813,"d":"1.24"},{"v":0.311220770950767,"d":"0.31"},1,1,"up","no"]
["MSTRG.13015","TSPO2","ENST00000373161;ENST00000373158;ENST00000470917","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0015485(cholesterol binding);GO:0015485(cholesterol binding)","NA","NA","NA","translocator protein 2 [Source:HGNC Symbol;Acc:HGNC:21256]",{"v":0.2373445,"d":"0.24"},{"v":0.371123188259109,"d":"0.37"},{"v":0.639530235535409,"d":"0.64"},{"v":-0.644915526826839,"d":"-0.64"},1,1,"down","no"]
["ENSG00000123572","NRK","ENST00000243300","GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0000185(activation of MAPKKK activity);GO:0005737(cytoplasm);GO:0048812(neuron projection morphogenesis);GO:0042981(regulation of apoptotic process);GO:0008349(MAP kinase kinase kinase kinase activity);GO:0007346(regulation of mitotic cell cycle);GO:0031098(stress-activated protein kinase signaling cascade);GO:0007256(activation of JNKK activity);GO:0007567(parturition);GO:0008285(negative regulation of cell proliferation);GO:0060721(regulation of spongiotrophoblast cell proliferation);GO:0016020(membrane);GO:0016021(integral component of membrane)","NA","NA","NA","Nik related kinase [Source:HGNC Symbol;Acc:HGNC:25391]",0,0,1,0,1,1,"no","no"]
["ENSG00000215837","SDHAP2","ENST00000455183","NA","NA","NA","NA","succinate dehydrogenase complex flavoprotein subunit A pseudogene 2 [Source:HGNC Symbol;Acc:HGNC:27408]",{"v":0.000707,"d":"0.00"},0,"inf","inf",1,1,"up","no"]
["MSTRG.1944","CYP17A1","ENST00000369887;ENST00000489268;ENST00000469683","GO:0046872(metal ion binding);GO:0004497(monooxygenase activity);GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0005506(iron ion binding);GO:0016705(oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen);GO:0020037(heme binding);GO:0016020(membrane);GO:0016829(lyase activity);GO:0006694(steroid biosynthetic process);GO:0008202(steroid metabolic process);GO:0042446(hormone biosynthetic process);GO:0005789(endoplasmic reticulum membrane);GO:0005783(endoplasmic reticulum);GO:0007548(sex differentiation);GO:0019825(oxygen binding);GO:0016125(sterol metabolic process);GO:0004508(steroid 17-alpha-monooxygenase activity);GO:0047442(17-alpha-hydroxyprogesterone aldolase activity);GO:0006702(androgen biosynthetic process);GO:0006704(glucocorticoid biosynthetic process);GO:0042448(progesterone metabolic process);GO:0005739(mitochondrion);GO:0030424(axon);GO:0043025(neuronal cell body);GO:0043025(neuronal cell body)","00140(Steroid hormone biosynthesis);04913(Ovarian Steroidogenesis);04917(Prolactin signaling pathway);04927(Cortisol synthesis and secretion);04927(Cortisol synthesis and secretion)","K00512","EC:1.14.14.19;EC:1.14.14.32","cytochrome P450 family 17 subfamily A member 1 [Source:HGNC Symbol;Acc:HGNC:2593]",{"v":0.0239479419448476,"d":"0.02"},{"v":0.0151637445573295,"d":"0.02"},{"v":1.5792894594279,"d":"1.58"},{"v":0.65927561920882,"d":"0.66"},1,1,"up","no"]
["ENSG00000248514","AC008443.4","ENST00000503314","NA","NA","NA","NA",null,0,{"v":0.048848,"d":"0.05"},"-inf","-inf",1,1,"down","no"]
["ENSG00000230736","AL021937.1","ENST00000420171","NA","NA","NA","NA",null,0,{"v":0.032665,"d":"0.03"},"-inf","-inf",1,1,"down","no"]
["ENSG00000203772","SPRN","ENST00000414069","GO:0016020(membrane);GO:0005886(plasma membrane);GO:0031225(anchored component of membrane);GO:0005576(extracellular region);GO:0006501(C-terminal protein lipidation);GO:0003676(nucleic acid binding);GO:0006606(protein import into nucleus);GO:0005634(nucleus);GO:0005730(nucleolus);GO:0005829(cytosol);GO:0031982(vesicle)","NA","NA","NA","shadow of prion protein [Source:HGNC Symbol;Acc:HGNC:16871]",{"v":0.117974,"d":"0.12"},{"v":0.269662,"d":"0.27"},{"v":0.437488411418739,"d":"0.44"},{"v":-1.19268329282273,"d":"-1.19"},1,1,"down","no"]
["ENSG00000165164","CFAP47","ENST00000378653","GO:0016020(membrane);GO:0016021(integral component of membrane)","NA","NA","NA","cilia and flagella associated protein 47 [Source:HGNC Symbol;Acc:HGNC:26708]",0,0,1,0,1,1,"no","no"]
["ENSG00000254106","LINC01848","ENST00000523446","NA","NA","NA","NA","long intergenic non-protein coding RNA 1848 [Source:HGNC Symbol;Acc:HGNC:52663]",0,0,1,0,1,1,"no","no"]
["ENSG00000257355","AC008770.2","ENST00000547473","GO:0003676(nucleic acid binding);GO:0006355(regulation of transcription, DNA-templated);GO:0005622(intracellular)","NA","NA","NA",null,{"v":0.146037,"d":"0.15"},{"v":0.003731,"d":"0.00"},{"v":39.1415170195658,"d":"39.14"},{"v":5.29062776690195,"d":"5.29"},1,1,"up","no"]
["MSTRG.15208","CXorf58","ENST00000379211","NA","NA","NA","NA","chromosome X open reading frame 58 [Source:HGNC Symbol;Acc:HGNC:26356]",{"v":0.0551893651948052,"d":"0.06"},0,"inf","inf",1,1,"up","no"]
["ENSG00000182566","CLEC4G","ENST00000328853","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0030246(carbohydrate binding);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0050776(regulation of immune response);GO:0046718(viral entry into host cell);GO:0016032(viral process);GO:0001618(virus receptor activity);GO:0030247(polysaccharide binding);GO:0002710(negative regulation of T cell mediated immunity);GO:0042130(negative regulation of T cell proliferation)","NA","NA","NA","C-type lectin domain family 4 member G [Source:HGNC Symbol;Acc:HGNC:24591]",{"v":0.0712720638540479,"d":"0.07"},{"v":0.115770581527936,"d":"0.12"},{"v":0.615631906771148,"d":"0.62"},{"v":-0.69986008975206,"d":"-0.70"},1,1,"down","no"]
["ENSG00000165868","HSPA12A","ENST00000635765;ENST00000369209;ENST00000481291","GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0003674(molecular_function);GO:0008150(biological_process);GO:0070062(extracellular exosome);GO:0070062(extracellular exosome)","NA","NA","NA","heat shock protein family A (Hsp70) member 12A [Source:HGNC Symbol;Acc:HGNC:19022]",{"v":0.00295712068965517,"d":"0.00"},{"v":0.0168030460245084,"d":"0.02"},{"v":0.175987180261365,"d":"0.18"},{"v":-2.50645775492802,"d":"-2.51"},1,1,"down","no"]
["ENSG00000239649","MYADML","ENST00000474610;ENST00000491596","NA","NA","NA","NA","myeloid associated differentiation marker like (pseudogene) [Source:HGNC Symbol;Acc:HGNC:31019]",0,0,1,0,1,1,"no","no"]
["ENSG00000149124","GLYAT","ENST00000278400","GO:0005739(mitochondrion);GO:0047961(glycine N-acyltransferase activity);GO:0016740(transferase activity);GO:0016746(transferase activity, transferring acyl groups);GO:0005515(protein binding);GO:0070062(extracellular exosome);GO:0005759(mitochondrial matrix);GO:0006805(xenobiotic metabolic process);GO:0009636(response to toxic substance);GO:0006544(glycine metabolic process);GO:0047962(glycine N-benzoyltransferase activity);GO:0006637(acyl-CoA metabolic process);GO:0032787(monocarboxylic acid metabolic process)","00360(Phenylalanine metabolism)","K00628","EC:2.3.1.13;EC:2.3.1.71","glycine-N-acyltransferase [Source:HGNC Symbol;Acc:HGNC:13734]",0,0,1,0,1,1,"no","no"]
["ENSG00000255148","AC239802.2","ENST00000532137","NA","NA","NA","NA",null,{"v":0.018415,"d":"0.02"},0,"inf","inf",1,1,"up","no"]
["ENSG00000015520","NPC1L1","ENST00000289547","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0006629(lipid metabolic process);GO:0008202(steroid metabolic process);GO:0005886(plasma membrane);GO:0030659(cytoplasmic vesicle membrane);GO:0031410(cytoplasmic vesicle);GO:0008203(cholesterol metabolic process);GO:0005515(protein binding);GO:0016324(apical plasma membrane);GO:0031489(myosin V binding);GO:0017137(Rab GTPase binding);GO:0030299(intestinal cholesterol absorption);GO:0030301(cholesterol transport);GO:0008144(drug binding);GO:0006695(cholesterol biosynthetic process);GO:0042157(lipoprotein metabolic process);GO:0042493(response to drug);GO:0098856(intestinal lipid absorption);GO:0031526(brush border membrane);GO:0005319(lipid transporter activity);GO:0006869(lipid transport)","04975(Fat digestion and absorption)","K14461","NA","NPC1 like intracellular cholesterol transporter 1 [Source:HGNC Symbol;Acc:HGNC:7898]",0,0,1,0,1,1,"no","no"]
["ENSG00000079112","CDH17","ENST00000027335;ENST00000450165","GO:0016020(membrane);GO:0005509(calcium ion binding);GO:0007155(cell adhesion);GO:0007156(homophilic cell adhesion via plasma membrane adhesion molecules);GO:0005886(plasma membrane);GO:0006810(transport);GO:0016021(integral component of membrane);GO:0046872(metal ion binding);GO:0005634(nucleus);GO:0030054(cell junction);GO:0007229(integrin-mediated signaling pathway);GO:0016323(basolateral plasma membrane);GO:0005215(transporter activity);GO:0005178(integrin binding);GO:0034332(adherens junction organization);GO:0016339(calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules);GO:0005427(proton-dependent oligopeptide secondary active transmembrane transporter activity);GO:0002314(germinal center B cell differentiation);GO:0002315(marginal zone B cell differentiation);GO:0006857(oligopeptide transport);GO:0030183(B cell differentiation);GO:0033626(positive regulation of integrin activation by cell surface receptor linked signal transduction);GO:0035672(oligopeptide transmembrane transport);GO:0048536(spleen development);GO:0009986(cell surface);GO:0009986(cell surface)","05226(Gastric cancer);05226(Gastric cancer)","K06811","NA","cadherin 17 [Source:HGNC Symbol;Acc:HGNC:1756]",0,{"v":0.0130460348628557,"d":"0.01"},"-inf","-inf",1,1,"down","no"]
["MSTRG.3773","AC026367.2","ENST00000610630","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000261739","GOLGA8S","ENST00000604046","GO:0005794(Golgi apparatus)","NA","NA","NA","golgin A8 family member S [Source:HGNC Symbol;Acc:HGNC:44409]",{"v":0.139143,"d":"0.14"},{"v":0.103739,"d":"0.10"},{"v":1.34127955735066,"d":"1.34"},{"v":0.423609963543488,"d":"0.42"},1,1,"up","no"]
["MSTRG.13511","AC080080.1","ENST00000625121","NA","NA","NA","NA",null,0,{"v":0.02103,"d":"0.02"},"-inf","-inf",1,1,"down","no"]
["ENSG00000236166","AL021408.1","ENST00000440246","NA","NA","NA","NA",null,{"v":0.071206327077748,"d":"0.07"},0,"inf","inf",1,1,"up","no"]
["ENSG00000240291","AL450384.2","ENST00000436485;ENST00000425669","NA","NA","NA","NA",null,{"v":0.262807555555556,"d":"0.26"},{"v":0.339385767619048,"d":"0.34"},{"v":0.774362335224826,"d":"0.77"},{"v":-0.368919312866088,"d":"-0.37"},1,1,"down","no"]
["ENSG00000279775","AC004585.2","ENST00000624090","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000152380","FAM151B","ENST00000509292;ENST00000511718;ENST00000502608;ENST00000282226","GO:0006629(lipid metabolic process);GO:0005515(protein binding);GO:0008081(phosphoric diester hydrolase activity);GO:0008081(phosphoric diester hydrolase activity)","NA","NA","NA","family with sequence similarity 151 member B [Source:HGNC Symbol;Acc:HGNC:33716]",{"v":0.24161520714056,"d":"0.24"},{"v":0.13611236957221,"d":"0.14"},{"v":1.77511572166392,"d":"1.78"},{"v":0.827913078492636,"d":"0.83"},1,1,"up","no"]
["ENSG00000279690","AP000280.1","ENST00000624800","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000282059","CICP19","ENST00000632944","NA","NA","NA","NA","capicua transcriptional repressor pseudogene 19 [Source:HGNC Symbol;Acc:HGNC:48829]",0,0,1,0,1,1,"no","no"]
["ENSG00000120322","PCDHB8","ENST00000239444","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0046872(metal ion binding);GO:0005509(calcium ion binding);GO:0007155(cell adhesion);GO:0007156(homophilic cell adhesion via plasma membrane adhesion molecules);GO:0005886(plasma membrane);GO:0005887(integral component of plasma membrane);GO:0042802(identical protein binding);GO:0007268(chemical synaptic transmission);GO:0007416(synapse assembly)","NA","NA","NA","protocadherin beta 8 [Source:HGNC Symbol;Acc:HGNC:8693]",{"v":0.004847,"d":"0.00"},0,"inf","inf",1,1,"up","no"]
["MSTRG.6620","ANKRD13B","ENST00000578943;ENST00000487527;ENST00000578811;ENST00000579719;ENST00000394859;ENST00000488766","GO:0016020(membrane);GO:0043231(intracellular membrane-bounded organelle);GO:0005886(plasma membrane);GO:0005737(cytoplasm);GO:0005768(endosome);GO:0005769(early endosome);GO:0005770(late endosome);GO:0005770(late endosome)","NA","NA","NA","ankyrin repeat domain 13B [Source:HGNC Symbol;Acc:HGNC:26363]",{"v":0.244859774615966,"d":"0.24"},{"v":0.0773535940569126,"d":"0.08"},{"v":3.16546086321227,"d":"3.17"},{"v":1.66241555863239,"d":"1.66"},1,1,"up","no"]
["ENSG00000225230","AC008937.1","ENST00000453721","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["MSTRG.14034","TAS2R38","ENST00000547270","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0004930(G-protein coupled receptor activity);GO:0007186(G-protein coupled receptor signaling pathway);GO:0004871(signal transducer activity);GO:0007165(signal transduction);GO:0050896(response to stimulus);GO:0005886(plasma membrane);GO:0050909(sensory perception of taste);GO:0001580(detection of chemical stimulus involved in sensory perception of bitter taste);GO:0033038(bitter taste receptor activity)","04742(Taste transduction)","K08474","NA","taste 2 receptor member 38 [Source:HGNC Symbol;Acc:HGNC:9584]",0,{"v":0.08905,"d":"0.09"},"-inf","-inf",1,1,"down","no"]
["ENSG00000234814","SVILP1","ENST00000422642","NA","NA","NA","NA","supervillin pseudogene 1 [Source:HGNC Symbol;Acc:HGNC:44959]",{"v":0.32693483539604,"d":"0.33"},{"v":0.197370731435644,"d":"0.20"},{"v":1.65645044236279,"d":"1.66"},{"v":0.728095041555393,"d":"0.73"},1,1,"up","no"]
["ENSG00000184058","TBX1","ENST00000332710;ENST00000329705","GO:0005634(nucleus);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0042803(protein homodimerization activity);GO:0007275(multicellular organism development);GO:0045893(positive regulation of transcription, DNA-templated);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0001934(positive regulation of protein phosphorylation);GO:0007507(heart development);GO:0008283(cell proliferation);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0007517(muscle organ development);GO:0007605(sensory perception of sound);GO:0008284(positive regulation of cell proliferation);GO:0043565(sequence-specific DNA binding);GO:0030855(epithelial cell differentiation);GO:0030878(thyroid gland development);GO:0048538(thymus development);GO:0060023(soft palate development);GO:0003151(outflow tract morphogenesis);GO:0060325(face morphogenesis);GO:0001525(angiogenesis);GO:0045596(negative regulation of cell differentiation);GO:0071300(cellular response to retinoic acid);GO:0044344(cellular response to fibroblast growth factor stimulus);GO:0043410(positive regulation of MAPK cascade);GO:0050679(positive regulation of epithelial cell proliferation);GO:0003007(heart morphogenesis);GO:0001568(blood vessel development);GO:0001708(cell fate specification);GO:0001755(neural crest cell migration);GO:0001945(lymph vessel development);GO:0002053(positive regulation of mesenchymal cell proliferation);GO:0003148(outflow tract septum morphogenesis);GO:0007368(determination of left/right symmetry);GO:0007389(pattern specification process);GO:0007498(mesoderm development);GO:0009952(anterior/posterior pattern specification);GO:0021644(vagus nerve morphogenesis);GO:0035176(social behavior);GO:0035909(aorta morphogenesis);GO:0042471(ear morphogenesis);GO:0042472(inner ear morphogenesis);GO:0042473(outer ear morphogenesis);GO:0042474(middle ear morphogenesis);GO:0042475(odontogenesis of dentin-containing tooth);GO:0042693(muscle cell fate commitment);GO:0043587(tongue morphogenesis);GO:0048384(retinoic acid receptor signaling pathway);GO:0048514(blood vessel morphogenesis);GO:0048644(muscle organ morphogenesis);GO:0048701(embryonic cranial skeleton morphogenesis);GO:0048703(embryonic viscerocranium morphogenesis);GO:0048752(semicircular canal morphogenesis);GO:0048844(artery morphogenesis);GO:0060017(parathyroid gland development);GO:0060037(pharyngeal system development);GO:0060415(muscle tissue morphogenesis);GO:0060982(coronary artery morphogenesis);GO:0070166(enamel mineralization);GO:0090103(cochlea morphogenesis);GO:0097152(mesenchymal cell apoptotic process);GO:2000027(regulation of organ morphogenesis);GO:2001037(positive regulation of tongue muscle cell differentiation);GO:2001054(negative regulation of mesenchymal cell apoptotic process);GO:2001054(negative regulation of mesenchymal cell apoptotic process)","NA","NA","NA","T-box 1 [Source:HGNC Symbol;Acc:HGNC:11592]",0,0,1,0,1,1,"no","no"]
["ENSG00000243806","RPL7P18","ENST00000478965","NA","NA","NA","NA","ribosomal protein L7 pseudogene 18 [Source:HGNC Symbol;Acc:HGNC:36949]",0,{"v":0.274585,"d":"0.27"},"-inf","-inf",1,1,"down","no"]
["MSTRG.12035","RPL29P12","ENST00000481681","NA","NA","NA","NA","ribosomal protein L29 pseudogene 12 [Source:HGNC Symbol;Acc:HGNC:36608]",{"v":0.0258,"d":"0.03"},0,"inf","inf",1,1,"up","no"]
["ENSG00000204532","ZSCAN5C","ENST00000534327","GO:0005634(nucleus);GO:0003676(nucleic acid binding);GO:0046872(metal ion binding);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0000981(RNA polymerase II transcription factor activity, sequence-specific DNA binding)","NA","NA","NA","zinc finger and SCAN domain containing 5C [Source:HGNC Symbol;Acc:HGNC:34294]",{"v":0.005113,"d":"0.01"},{"v":0.033753,"d":"0.03"},{"v":0.151482831155749,"d":"0.15"},{"v":-2.72277380488597,"d":"-2.72"},1,1,"down","no"]
["ENSG00000241735","FABP5P3","ENST00000477993","NA","NA","NA","NA","fatty acid binding protein 5 pseudogene 3 [Source:HGNC Symbol;Acc:HGNC:22573]",0,{"v":0.014453,"d":"0.01"},"-inf","-inf",1,1,"down","no"]
["ENSG00000010379","SLC6A13","ENST00000542272;ENST00000343164","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005887(integral component of plasma membrane);GO:0015293(symporter activity);GO:0055085(transmembrane transport);GO:0005886(plasma membrane);GO:0005328(neurotransmitter:sodium symporter activity);GO:0005332(gamma-aminobutyric acid:sodium symporter activity);GO:0006836(neurotransmitter transport);GO:0070062(extracellular exosome);GO:0005215(transporter activity);GO:0015812(gamma-aminobutyric acid transport);GO:0015812(gamma-aminobutyric acid transport)","04727(GABAergic synapse);04727(GABAergic synapse)","K05039","NA","solute carrier family 6 member 13 [Source:HGNC Symbol;Acc:HGNC:11046]",{"v":0.0125193341975018,"d":"0.01"},0,"inf","inf",1,1,"up","no"]
["ENSG00000229477","FAM90A16P","ENST00000526662","NA","NA","NA","NA","family with sequence similarity 90 member A16, pseudogene [Source:HGNC Symbol;Acc:HGNC:32264]",0,0,1,0,1,1,"no","no"]
["ENSG00000261557","AC092725.2","ENST00000567658","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000104055","TGM5","ENST00000220420","GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0016740(transferase activity);GO:0016746(transferase activity, transferring acyl groups);GO:0005886(plasma membrane);GO:0003810(protein-glutamine gamma-glutamyltransferase activity);GO:0018149(peptide cross-linking);GO:0006464(cellular protein modification process);GO:0008544(epidermis development);GO:0070268(cornification)","NA","NA","NA","transglutaminase 5 [Source:HGNC Symbol;Acc:HGNC:11781]",{"v":0.0146298171302671,"d":"0.01"},0,"inf","inf",1,1,"up","no"]
["ENSG00000156486","KCNS2","ENST00000287042;ENST00000521839","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0055085(transmembrane transport);GO:0005216(ion channel activity);GO:0006811(ion transport);GO:0005244(voltage-gated ion channel activity);GO:0005249(voltage-gated potassium channel activity);GO:0005267(potassium channel activity);GO:0006813(potassium ion transport);GO:0034765(regulation of ion transmembrane transport);GO:0051260(protein homooligomerization);GO:0071805(potassium ion transmembrane transport);GO:0008076(voltage-gated potassium channel complex);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0048471(perinuclear region of cytoplasm);GO:1902259(regulation of delayed rectifier potassium channel activity);GO:1902259(regulation of delayed rectifier potassium channel activity)","NA","NA","NA","potassium voltage-gated channel modifier subfamily S member 2 [Source:HGNC Symbol;Acc:HGNC:6301]",0,0,1,0,1,1,"no","no"]
["MSTRG.8361","AC063977.1","ENST00000600623","NA","NA","NA","NA",null,0,{"v":0.225005,"d":"0.23"},"-inf","-inf",1,1,"down","no"]
["ENSG00000226806","AC011893.1","ENST00000437007","NA","NA","NA","NA",null,{"v":0.142453,"d":"0.14"},{"v":0.163991,"d":"0.16"},{"v":0.868663524217792,"d":"0.87"},{"v":-0.203130635852262,"d":"-0.20"},1,1,"down","no"]
["ENSG00000250144","AC104619.3","ENST00000509116","NA","NA","NA","NA",null,0,{"v":0.017617,"d":"0.02"},"-inf","-inf",1,1,"down","no"]
["ENSG00000236008","LINC01814","ENST00000454224;ENST00000436187","NA","NA","NA","NA","long intergenic non-protein coding RNA 1814 [Source:HGNC Symbol;Acc:HGNC:52618]",{"v":0.0194822006476105,"d":"0.02"},{"v":0.0056827782492184,"d":"0.01"},{"v":3.42828802976608,"d":"3.43"},{"v":1.77748832346989,"d":"1.78"},1,1,"up","no"]
["MSTRG.14525","AC021733.1","ENST00000519786","NA","NA","NA","NA",null,0,{"v":0.062636,"d":"0.06"},"-inf","-inf",1,1,"down","no"]
["ENSG00000280171","AC010329.5","ENST00000623497","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000133169","BEX1","ENST00000372728","GO:0051091(positive regulation of sequence-specific DNA binding transcription factor activity);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005515(protein binding);GO:0007275(multicellular organism development);GO:0007399(nervous system development);GO:0030154(cell differentiation);GO:0005667(transcription factor complex);GO:0001102(RNA polymerase II activating transcription factor binding)","NA","NA","NA","brain expressed X-linked 1 [Source:HGNC Symbol;Acc:HGNC:1036]",0,{"v":0.353415,"d":"0.35"},"-inf","-inf",1,1,"down","no"]
["MSTRG.11797","AC004067.1","ENST00000608733","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000138615","CILP","ENST00000261883","GO:0005615(extracellular space);GO:0043569(negative regulation of insulin-like growth factor receptor signaling pathway);GO:0005576(extracellular region);GO:0005578(proteinaceous extracellular matrix);GO:0070062(extracellular exosome);GO:0031012(extracellular matrix)","NA","NA","NA","cartilage intermediate layer protein [Source:HGNC Symbol;Acc:HGNC:1980]",{"v":0.009327,"d":"0.01"},0,"inf","inf",1,1,"up","no"]
["ENSG00000224093","AL109613.1","ENST00000412628;ENST00000446684","NA","NA","NA","NA",null,{"v":0.0252922927328557,"d":"0.03"},0,"inf","inf",1,1,"up","no"]
["ENSG00000231527","CR769775.1","ENST00000612999","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000177776","AC005519.1","ENST00000554490","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000178081","ULK4P3","ENST00000568486;ENST00000563895;ENST00000565158","NA","NA","NA","NA","ULK4 pseudogene 3 [Source:HGNC Symbol;Acc:HGNC:15777]",{"v":0.0788470100874244,"d":"0.08"},{"v":0.0684203174176194,"d":"0.07"},{"v":1.15239176115134,"d":"1.15"},{"v":0.204631251319734,"d":"0.20"},1,1,"up","no"]
["ENSG00000198454","PRR31","ENST00000371629","NA","NA","NA","NA","proline rich 31 [Source:HGNC Symbol;Acc:HGNC:18147]",0,{"v":0.047081,"d":"0.05"},"-inf","-inf",1,1,"down","no"]
["ENSG00000157103","SLC6A1","ENST00000287766","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0046872(metal ion binding);GO:0005887(integral component of plasma membrane);GO:0015293(symporter activity);GO:0055085(transmembrane transport);GO:0005886(plasma membrane);GO:0005328(neurotransmitter:sodium symporter activity);GO:0005332(gamma-aminobutyric acid:sodium symporter activity);GO:0006836(neurotransmitter transport);GO:0007612(learning);GO:0009636(response to toxic substance);GO:0009744(response to sucrose);GO:0010033(response to organic substance);GO:0010243(response to organonitrogen compound);GO:0010288(response to lead ion);GO:0014054(positive regulation of gamma-aminobutyric acid secretion);GO:0014070(response to organic cyclic compound);GO:0014074(response to purine-containing compound);GO:0032229(negative regulation of synaptic transmission, GABAergic);GO:0032355(response to estradiol);GO:0042220(response to cocaine);GO:0051260(protein homooligomerization);GO:0051592(response to calcium ion);GO:0051939(gamma-aminobutyric acid import);GO:0009986(cell surface);GO:0030424(axon);GO:0043005(neuron projection);GO:0007268(chemical synaptic transmission);GO:0015812(gamma-aminobutyric acid transport)","04727(GABAergic synapse)","K05034","NA","solute carrier family 6 member 1 [Source:HGNC Symbol;Acc:HGNC:11042]",0,0,1,0,1,1,"no","no"]
["ENSG00000164756","SLC30A8","ENST00000427715","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0055085(transmembrane transport);GO:0098655(cation transmembrane transport);GO:0006811(ion transport);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0006812(cation transport);GO:0031410(cytoplasmic vesicle);GO:0005385(zinc ion transmembrane transporter activity);GO:0006882(cellular zinc ion homeostasis);GO:0071577(zinc II ion transmembrane transport);GO:0008324(cation transmembrane transporter activity);GO:0042803(protein homodimerization activity);GO:0032024(positive regulation of insulin secretion);GO:0030667(secretory granule membrane);GO:0061088(regulation of sequestering of zinc ion);GO:0060627(regulation of vesicle-mediated transport);GO:0006829(zinc II ion transport);GO:0010043(response to zinc ion);GO:0030658(transport vesicle membrane);GO:0008270(zinc ion binding);GO:0009749(response to glucose);GO:0030141(secretory granule);GO:0030073(insulin secretion);GO:0032119(sequestering of zinc ion);GO:0005623(cell);GO:0034341(response to interferon-gamma);GO:0070555(response to interleukin-1)","NA","NA","NA","solute carrier family 30 member 8 [Source:HGNC Symbol;Acc:HGNC:20303]",0,0,1,0,1,1,"no","no"]
["MSTRG.3636","AC008126.1","ENST00000549019","NA","NA","NA","NA",null,0,{"v":0.068109,"d":"0.07"},"-inf","-inf",1,1,"down","no"]
["ENSG00000262412","AL160291.1","ENST00000574842","NA","NA","NA","NA",null,{"v":0.159392,"d":"0.16"},{"v":0.047221,"d":"0.05"},{"v":3.37544736452002,"d":"3.38"},{"v":1.75507872225322,"d":"1.76"},1,1,"up","no"]
["MSTRG.5551","CEMP1","ENST00000567119;ENST00000565480","GO:0005737(cytoplasm);GO:0005737(cytoplasm)","NA","NA","NA","cementum protein 1 [Source:HGNC Symbol;Acc:HGNC:32553]",0,{"v":0.0724919370932755,"d":"0.07"},"-inf","-inf",1,1,"down","no"]
["ENSG00000197790","OR52M1","ENST00000360213","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0004930(G-protein coupled receptor activity);GO:0007186(G-protein coupled receptor signaling pathway);GO:0005886(plasma membrane);GO:0004871(signal transducer activity);GO:0007165(signal transduction);GO:0004984(olfactory receptor activity);GO:0007608(sensory perception of smell);GO:0050896(response to stimulus);GO:0050911(detection of chemical stimulus involved in sensory perception of smell)","04740(Olfactory transduction)","K04257","NA","olfactory receptor family 52 subfamily M member 1 [Source:HGNC Symbol;Acc:HGNC:15225]",0,0,1,0,1,1,"no","no"]
["ENSG00000214244","SETP21","ENST00000514799","NA","NA","NA","NA","SET pseudogene 21 [Source:HGNC Symbol;Acc:HGNC:42940]",{"v":0.028987,"d":"0.03"},0,"inf","inf",1,1,"up","no"]
["ENSG00000123201","GUCY1B2","ENST00000389600;ENST00000531898","NA","NA","NA","NA","guanylate cyclase 1 soluble subunit beta 2 (pseudogene) [Source:HGNC Symbol;Acc:HGNC:4686]",0,{"v":0.0104921120689655,"d":"0.01"},"-inf","-inf",1,1,"down","no"]
["ENSG00000178645","C10orf53","ENST00000374113","NA","NA","NA","NA","chromosome 10 open reading frame 53 [Source:HGNC Symbol;Acc:HGNC:27421]",0,0,1,0,1,1,"no","no"]
["ENSG00000184659","FOXD4L4","ENST00000377413","GO:0005634(nucleus);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0043565(sequence-specific DNA binding);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0000981(RNA polymerase II transcription factor activity, sequence-specific DNA binding);GO:0009653(anatomical structure morphogenesis);GO:0030154(cell differentiation)","NA","NA","NA","forkhead box D4 like 4 [Source:HGNC Symbol;Acc:HGNC:23762]",0,0,1,0,1,1,"no","no"]
["MSTRG.5734","REXO5","ENST00000563068;ENST00000563045;ENST00000261377;ENST00000563617","GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0016787(hydrolase activity);GO:0090305(nucleic acid phosphodiester bond hydrolysis);GO:0004527(exonuclease activity);GO:0004518(nuclease activity);GO:0070062(extracellular exosome);GO:0005730(nucleolus);GO:0005730(nucleolus)","03008(Ribosome biogenesis in eukaryotes);03008(Ribosome biogenesis in eukaryotes)","K14570","EC:3.1.-.-","RNA exonuclease 5 [Source:HGNC Symbol;Acc:HGNC:24661]",{"v":0.128862894263491,"d":"0.13"},{"v":0.202285009722897,"d":"0.20"},{"v":0.637036300613751,"d":"0.64"},{"v":-0.650552510124348,"d":"-0.65"},1,1,"down","no"]
["ENSG00000129862","VCY1B","ENST00000250823","GO:0007420(brain development)","NA","NA","NA","variable charge, Y-linked 1B [Source:HGNC Symbol;Acc:HGNC:31751]",0,0,1,0,1,1,"no","no"]
["MSTRG.8859","AC093162.2","ENST00000501107","NA","NA","NA","NA",null,{"v":2.642332,"d":"2.64"},{"v":0.568487,"d":"0.57"},{"v":4.6480077820601,"d":"4.65"},{"v":2.21661248421794,"d":"2.22"},1,1,"up","no"]
["ENSG00000167014","TERB2","ENST00000559137;ENST00000557864","GO:0005634(nucleus);GO:0016020(membrane);GO:0005694(chromosome);GO:0000781(chromosome, telomeric region);GO:0005637(nuclear inner membrane);GO:0007129(synapsis);GO:0000784(nuclear chromosome, telomeric region);GO:0045141(meiotic telomere clustering);GO:0070197(meiotic attachment of telomere to nuclear envelope);GO:0070197(meiotic attachment of telomere to nuclear envelope)","NA","NA","NA","telomere repeat binding bouquet formation protein 2 [Source:HGNC Symbol;Acc:HGNC:28520]",0,{"v":0.0029462508406187,"d":"0.00"},"-inf","-inf",1,1,"down","no"]
["ENSG00000106341","PPP1R17","ENST00000342032","GO:0005622(intracellular);GO:0004864(protein phosphatase inhibitor activity);GO:0043086(negative regulation of catalytic activity);GO:0004865(protein serine/threonine phosphatase inhibitor activity);GO:0019212(phosphatase inhibitor activity);GO:0010921(regulation of phosphatase activity);GO:0005575(cellular_component);GO:0035556(intracellular signal transduction);GO:0007417(central nervous system development)","04730(Long-term depression)","K08067","NA","protein phosphatase 1 regulatory subunit 17 [Source:HGNC Symbol;Acc:HGNC:16973]",{"v":0.0445637265100671,"d":"0.04"},{"v":0.103838058724832,"d":"0.10"},{"v":0.429165635965516,"d":"0.43"},{"v":-1.22039353325456,"d":"-1.22"},1,1,"down","no"]
["MSTRG.6734","AC015849.4","ENST00000603678","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000207389","RNU1-4","ENST00000384659","NA","NA","NA","NA","RNA, U1 small nuclear 4 [Source:HGNC Symbol;Acc:HGNC:10128]",0,{"v":0.026613,"d":"0.03"},"-inf","-inf",1,1,"down","no"]
["ENSG00000213028","AL354983.1","ENST00000434580","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["MSTRG.15381","HMGN5","ENST00000436386;ENST00000430960;ENST00000358130;ENST00000451455;ENST00000373250","GO:0005634(nucleus);GO:0003723(RNA binding);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0016569(covalent chromatin modification);GO:0003677(DNA binding);GO:0031492(nucleosomal DNA binding);GO:0000785(chromatin);GO:0045893(positive regulation of transcription, DNA-templated);GO:0003682(chromatin binding);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0010628(positive regulation of gene expression);GO:0043066(negative regulation of apoptotic process);GO:0008284(positive regulation of cell proliferation);GO:0006325(chromatin organization);GO:0006749(glutathione metabolic process);GO:0071157(negative regulation of cell cycle arrest);GO:0005654(nucleoplasm);GO:0005654(nucleoplasm)","NA","NA","NA","high mobility group nucleosome binding domain 5 [Source:HGNC Symbol;Acc:HGNC:8013]",{"v":0.377391568708609,"d":"0.38"},{"v":0.197524598509934,"d":"0.20"},{"v":1.91060542107432,"d":"1.91"},{"v":0.934029863173112,"d":"0.93"},1,1,"up","no"]
["ENSG00000176532","PRR15","ENST00000319694","GO:0007275(multicellular organism development)","NA","NA","NA","proline rich 15 [Source:HGNC Symbol;Acc:HGNC:22310]",{"v":0.0134002946518668,"d":"0.01"},0,"inf","inf",1,1,"up","no"]
["ENSG00000264196","AC011120.1","ENST00000583916","NA","NA","NA","NA",null,{"v":0.064421,"d":"0.06"},0,"inf","inf",1,1,"up","no"]
["ENSG00000176678","FOXL1","ENST00000320241","GO:0005634(nucleus);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0043565(sequence-specific DNA binding);GO:0006351(transcription, DNA-templated);GO:0007275(multicellular organism development);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0000981(RNA polymerase II transcription factor activity, sequence-specific DNA binding);GO:0009653(anatomical structure morphogenesis);GO:0030154(cell differentiation);GO:0009887(animal organ morphogenesis);GO:0008301(DNA binding, bending);GO:0030111(regulation of Wnt signaling pathway);GO:0007507(heart development);GO:0007495(visceral mesoderm-endoderm interaction involved in midgut development);GO:0030166(proteoglycan biosynthetic process);GO:0061146(Peyer's patch morphogenesis)","NA","NA","NA","forkhead box L1 [Source:HGNC Symbol;Acc:HGNC:3817]",0,0,1,0,1,1,"no","no"]
["ENSG00000164929","BAALC","ENST00000306391;ENST00000309982;ENST00000438105;ENST00000297574","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005634(nucleus);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0030054(cell junction);GO:0045202(synapse);GO:0045211(postsynaptic membrane);GO:0045121(membrane raft);GO:0014069(postsynaptic density);GO:0043005(neuron projection);GO:0043005(neuron projection)","NA","NA","NA","BAALC, MAP3K1 and KLF4 binding [Source:HGNC Symbol;Acc:HGNC:14333]",{"v":0.0664494163122342,"d":"0.07"},{"v":0.127114102326745,"d":"0.13"},{"v":0.522754085470603,"d":"0.52"},{"v":-0.935795662959842,"d":"-0.94"},1,1,"down","no"]
["ENSG00000241997","RN7SL323P","ENST00000494712","NA","NA","NA","NA","RNA, 7SL, cytoplasmic 323, pseudogene [Source:HGNC Symbol;Acc:HGNC:46339]",{"v":0.180067,"d":"0.18"},0,"inf","inf",1,1,"up","no"]
["ENSG00000235297","AC008021.1","ENST00000474180","NA","NA","NA","NA",null,{"v":0.043336,"d":"0.04"},{"v":0.061463,"d":"0.06"},{"v":0.705074597725461,"d":"0.71"},{"v":-0.504152190460856,"d":"-0.50"},1,1,"down","no"]
["ENSG00000105131","EPHX3","ENST00000221730","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016787(hydrolase activity);GO:0003824(catalytic activity);GO:0005576(extracellular region);GO:0003674(molecular_function);GO:0008150(biological_process);GO:0005575(cellular_component)","NA","NA","NA","epoxide hydrolase 3 [Source:HGNC Symbol;Acc:HGNC:23760]",{"v":0.0783477915437562,"d":"0.08"},0,"inf","inf",1,1,"up","no"]
["MSTRG.8115","AC008649.1","ENST00000589557","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000175676","GOLGA8EP","ENST00000620011","NA","NA","NA","NA","golgin A8 family member E, pseudogene [Source:HGNC Symbol;Acc:HGNC:32377]",0,0,1,0,1,1,"no","no"]
["ENSG00000185873","TMPRSS11B","ENST00000332644","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016787(hydrolase activity);GO:0005887(integral component of plasma membrane);GO:0005576(extracellular region);GO:0005886(plasma membrane);GO:0008233(peptidase activity);GO:0006508(proteolysis);GO:0004252(serine-type endopeptidase activity);GO:0008236(serine-type peptidase activity);GO:0008150(biological_process);GO:0070062(extracellular exosome)","NA","NA","NA","transmembrane protease, serine 11B [Source:HGNC Symbol;Acc:HGNC:25398]",0,0,1,0,1,1,"no","no"]
["ENSG00000213892","CEACAM16","ENST00000405314","GO:0005576(extracellular region);GO:0005615(extracellular space);GO:0007605(sensory perception of sound);GO:0042802(identical protein binding);GO:0032426(stereocilium tip)","NA","NA","NA","carcinoembryonic antigen related cell adhesion molecule 16 [Source:HGNC Symbol;Acc:HGNC:31948]",0,0,1,0,1,1,"no","no"]
["ENSG00000262959","RPL23AP86","ENST00000573796","NA","NA","NA","NA","ribosomal protein L23a pseudogene 86 [Source:HGNC Symbol;Acc:HGNC:51577]",0,0,1,0,1,1,"no","no"]
["ENSG00000087842","PIR","ENST00000380421;ENST00000380420","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0005829(cytosol);GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0051213(dioxygenase activity);GO:0005515(protein binding);GO:0005654(nucleoplasm);GO:0006366(transcription from RNA polymerase II promoter);GO:0003712(transcription cofactor activity);GO:0008127(quercetin 2,3-dioxygenase activity);GO:0007586(digestion);GO:0030224(monocyte differentiation);GO:0030099(myeloid cell differentiation);GO:0030099(myeloid cell differentiation)","NA","NA","NA","pirin [Source:HGNC Symbol;Acc:HGNC:30048]",{"v":0.0423627547770701,"d":"0.04"},{"v":0.0404520513535032,"d":"0.04"},{"v":1.04723378319852,"d":"1.05"},{"v":0.0665835437124661,"d":"0.07"},1,1,"up","no"]
["ENSG00000275542","AC027601.3","ENST00000622907","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000228918","LINC01344","ENST00000608183;ENST00000420760","NA","NA","NA","NA","long intergenic non-protein coding RNA 1344 [Source:HGNC Symbol;Acc:HGNC:50554]",0,0,1,0,1,1,"no","no"]
["ENSG00000142233","NTN5","ENST00000600468;ENST00000270235","GO:0005576(extracellular region);GO:0005576(extracellular region)","NA","NA","NA","netrin 5 [Source:HGNC Symbol;Acc:HGNC:25208]",0,{"v":0.0149308353130016,"d":"0.01"},"-inf","-inf",1,1,"down","no"]
["ENSG00000282143","AL137798.2","ENST00000633763","NA","NA","NA","NA",null,{"v":0.032294,"d":"0.03"},0,"inf","inf",1,1,"up","no"]
["ENSG00000187323","DCC","ENST00000442544","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0006915(apoptotic process);GO:0005515(protein binding);GO:0007399(nervous system development);GO:0007411(axon guidance);GO:0007275(multicellular organism development);GO:0005886(plasma membrane);GO:0005829(cytosol);GO:0005042(netrin receptor activity);GO:0038007(netrin-activated signaling pathway);GO:0004888(transmembrane signaling receptor activity);GO:0007409(axonogenesis);GO:1901214(regulation of neuron death);GO:0097192(extrinsic apoptotic signaling pathway in absence of ligand);GO:0001764(neuron migration);GO:0010977(negative regulation of neuron projection development);GO:0021965(spinal cord ventral commissure morphogenesis);GO:0033563(dorsal/ventral axon guidance);GO:0033564(anterior/posterior axon guidance);GO:0048671(negative regulation of collateral sprouting);GO:2000171(negative regulation of dendrite development);GO:0030424(axon);GO:0005887(integral component of plasma membrane);GO:0055072(iron ion homeostasis);GO:0004872(receptor activity);GO:0030513(positive regulation of BMP signaling pathway)","04360(Axon guidance);05200(Pathways in cancer);05210(Colorectal cancer)","K06765","NA","DCC netrin 1 receptor [Source:HGNC Symbol;Acc:HGNC:2701]",0,0,1,0,1,1,"no","no"]
["ENSG00000271795","AC011337.1","ENST00000606930","NA","NA","NA","NA",null,{"v":0.155133,"d":"0.16"},{"v":0.015202,"d":"0.02"},{"v":10.2047756874096,"d":"10.20"},{"v":3.35117256552663,"d":"3.35"},1,1,"up","no"]
["ENSG00000241186","TDGF1","ENST00000296145","GO:0008083(growth factor activity);GO:0016020(membrane);GO:0005886(plasma membrane);GO:0005615(extracellular space);GO:0030154(cell differentiation);GO:0031225(anchored component of membrane);GO:0045121(membrane raft);GO:0007507(heart development);GO:0005515(protein binding);GO:0030335(positive regulation of cell migration);GO:0071346(cellular response to interferon-gamma);GO:0071356(cellular response to tumor necrosis factor);GO:0005102(receptor binding);GO:0008284(positive regulation of cell proliferation);GO:0043066(negative regulation of apoptotic process);GO:0016324(apical plasma membrane);GO:0009986(cell surface);GO:0009790(embryo development);GO:0009966(regulation of signal transduction);GO:0010595(positive regulation of endothelial cell migration);GO:0044344(cellular response to fibroblast growth factor stimulus);GO:0008595(anterior/posterior axis specification, embryo);GO:0030879(mammary gland development);GO:0035019(somatic stem cell population maintenance);GO:0000187(activation of MAPK activity);GO:0050731(positive regulation of peptidyl-tyrosine phosphorylation);GO:0071364(cellular response to epidermal growth factor stimulus);GO:0018105(peptidyl-serine phosphorylation);GO:0001763(morphogenesis of a branching structure);GO:0002042(cell migration involved in sprouting angiogenesis);GO:0035729(cellular response to hepatocyte growth factor stimulus);GO:0071354(cellular response to interleukin-6);GO:0019897(extrinsic component of plasma membrane)","NA","NA","NA","teratocarcinoma-derived growth factor 1 [Source:HGNC Symbol;Acc:HGNC:11701]",0,0,1,0,1,1,"no","no"]
["ENSG00000091482","SMPX","ENST00000379494","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005927(muscle tendon junction);GO:0031430(M band);GO:0043034(costamere);GO:0043292(contractile fiber);GO:0006941(striated muscle contraction)","NA","NA","NA","small muscle protein, X-linked [Source:HGNC Symbol;Acc:HGNC:11122]",0,0,1,0,1,1,"no","no"]
["ENSG00000242390","RPL6P9","ENST00000466502","NA","NA","NA","NA","ribosomal protein L6 pseudogene 9 [Source:HGNC Symbol;Acc:HGNC:36484]",{"v":0.03092,"d":"0.03"},0,"inf","inf",1,1,"up","no"]
["ENSG00000013293","SLC7A14","ENST00000231706","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005765(lysosomal membrane);GO:0015171(amino acid transmembrane transporter activity);GO:0003333(amino acid transmembrane transport);GO:0005764(lysosome);GO:0006865(amino acid transport);GO:0010923(negative regulation of phosphatase activity)","NA","NA","NA","solute carrier family 7 member 14 [Source:HGNC Symbol;Acc:HGNC:29326]",0,0,1,0,1,1,"no","no"]
["MSTRG.86","AL513477.1","ENST00000602865","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["MSTRG.1603","AC069549.1","ENST00000451584","NA","NA","NA","NA",null,{"v":0.13931,"d":"0.14"},{"v":0.060729,"d":"0.06"},{"v":2.2939616986942,"d":"2.29"},{"v":1.19784130348746,"d":"1.20"},1,1,"up","no"]
["ENSG00000274215","AC106028.4","ENST00000614509","NA","NA","NA","NA",null,{"v":0.366855,"d":"0.37"},0,"inf","inf",1,1,"up","no"]
["ENSG00000243636","AL445493.2","ENST00000442684","NA","NA","NA","NA",null,{"v":0.112423,"d":"0.11"},0,"inf","inf",1,1,"up","no"]
["ENSG00000278158","AP001059.3","ENST00000619053","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000277738","AC126175.1","ENST00000617041","NA","NA","NA","NA",null,{"v":0.070079,"d":"0.07"},0,"inf","inf",1,1,"up","no"]
["MSTRG.15078","ADAMTS13","ENST00000371929","GO:0008270(zinc ion binding);GO:0006508(proteolysis);GO:0004222(metalloendopeptidase activity);GO:0008237(metallopeptidase activity);GO:0046872(metal ion binding);GO:0016787(hydrolase activity);GO:0005515(protein binding);GO:0008233(peptidase activity);GO:0005576(extracellular region);GO:0005578(proteinaceous extracellular matrix);GO:0007229(integrin-mediated signaling pathway);GO:0005509(calcium ion binding);GO:0009986(cell surface);GO:0005178(integrin binding);GO:0007596(blood coagulation);GO:0007599(hemostasis);GO:0005788(endoplasmic reticulum lumen);GO:0007160(cell-matrix adhesion);GO:0043171(peptide catabolic process);GO:0030168(platelet activation);GO:0036066(protein O-linked fucosylation);GO:0016485(protein processing);GO:0009100(glycoprotein metabolic process);GO:0004175(endopeptidase activity);GO:0009636(response to toxic substance);GO:0014075(response to amine);GO:0034341(response to interferon-gamma);GO:0034612(response to tumor necrosis factor);GO:0035864(response to potassium ion);GO:0070670(response to interleukin-4);GO:0071222(cellular response to lipopolysaccharide);GO:0071346(cellular response to interferon-gamma);GO:0071353(cellular response to interleukin-4);GO:0071356(cellular response to tumor necrosis factor);GO:0005615(extracellular space)","NA","NA","NA","ADAM metallopeptidase with thrombospondin type 1 motif 13 [Source:HGNC Symbol;Acc:HGNC:1366]",{"v":0.0393821023125438,"d":"0.04"},{"v":0.0235998717589348,"d":"0.02"},{"v":1.66874221668742,"d":"1.67"},{"v":0.738761107827822,"d":"0.74"},1,1,"up","no"]
["MSTRG.13356","AL355312.3","ENST00000472053","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000180433","OR6K6","ENST00000368144;ENST00000641861","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0004930(G-protein coupled receptor activity);GO:0007186(G-protein coupled receptor signaling pathway);GO:0005886(plasma membrane);GO:0004871(signal transducer activity);GO:0007165(signal transduction);GO:0004984(olfactory receptor activity);GO:0007608(sensory perception of smell);GO:0050896(response to stimulus);GO:0050911(detection of chemical stimulus involved in sensory perception of smell);GO:0004888(transmembrane signaling receptor activity);GO:0050907(detection of chemical stimulus involved in sensory perception);GO:0050907(detection of chemical stimulus involved in sensory perception)","04740(Olfactory transduction);04740(Olfactory transduction)","K04257","NA","olfactory receptor family 6 subfamily K member 6 [Source:HGNC Symbol;Acc:HGNC:15033]",0,0,1,0,1,1,"no","no"]
["ENSG00000267723","AC011509.2","ENST00000592263","NA","NA","NA","NA",null,0,{"v":0.080464,"d":"0.08"},"-inf","-inf",1,1,"down","no"]
["MSTRG.15138","MT-ATP6","MSTRG.15138.1","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000102468","HTR2A","ENST00000542664;ENST00000612998;ENST00000378688","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0004930(G-protein coupled receptor activity);GO:0007186(G-protein coupled receptor signaling pathway);GO:0005887(integral component of plasma membrane);GO:0005886(plasma membrane);GO:0042995(cell projection);GO:0004871(signal transducer activity);GO:0007165(signal transduction);GO:0005901(caveola);GO:0031410(cytoplasmic vesicle);GO:0030425(dendrite);GO:0004993(G-protein coupled serotonin receptor activity);GO:0006939(smooth muscle contraction);GO:0046883(regulation of hormone secretion);GO:0050795(regulation of behavior);GO:0043198(dendritic shaft);GO:0046718(viral entry into host cell);GO:0030424(axon);GO:0016032(viral process);GO:0070374(positive regulation of ERK1 and ERK2 cascade);GO:0014065(phosphatidylinositol 3-kinase signaling);GO:0008144(drug binding);GO:0007268(chemical synaptic transmission);GO:0001618(virus receptor activity);GO:0007200(phospholipase C-activating G-protein coupled receptor signaling pathway);GO:0030594(neurotransmitter receptor activity);GO:0006874(cellular calcium ion homeostasis);GO:0042493(response to drug);GO:0051209(release of sequestered calcium ion into cytosol);GO:0007202(activation of phospholipase C activity);GO:0007210(serotonin receptor signaling pathway);GO:0007610(behavior);GO:0010513(positive regulation of phosphatidylinositol biosynthetic process);GO:0051378(serotonin binding);GO:0071886(1-(4-iodo-2,5-dimethoxyphenyl)propan-2-amine binding);GO:0098664(G-protein coupled serotonin receptor signaling pathway);GO:0001965(G-protein alpha-subunit binding);GO:0032403(protein complex binding);GO:0001659(temperature homeostasis);GO:0007204(positive regulation of cytosolic calcium ion concentration);GO:0007208(phospholipase C-activating serotonin receptor signaling pathway);GO:0007568(aging);GO:0007613(memory);GO:0008219(cell death);GO:0008284(positive regulation of cell proliferation);GO:0014059(regulation of dopamine secretion);GO:0014824(artery smooth muscle contraction);GO:0014832(urinary bladder smooth muscle contraction);GO:0019233(sensory perception of pain);GO:0030431(sleep);GO:0033674(positive regulation of kinase activity);GO:0043267(negative regulation of potassium ion transport);GO:0043406(positive regulation of MAP kinase activity);GO:0044380(protein localization to cytoskeleton);GO:0045600(positive regulation of fat cell differentiation);GO:0045821(positive regulation of glycolytic process);GO:0045907(positive regulation of vasoconstriction);GO:0048148(behavioral response to cocaine);GO:0050731(positive regulation of peptidyl-tyrosine phosphorylation);GO:0050965(detection of temperature stimulus involved in sensory perception of pain);GO:0050966(detection of mechanical stimulus involved in sensory perception of pain);GO:0051967(negative regulation of synaptic transmission, glutamatergic);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0043025(neuronal cell body);GO:0070852(cell body fiber);GO:0070852(cell body fiber)","04020(Calcium signaling pathway);04080(Neuroactive ligand-receptor interaction);04540(Gap junction);04726(Serotonergic synapse);04750(Inflammatory mediator regulation of TRP channels);04750(Inflammatory mediator regulation of TRP channels)","K04157","NA","5-hydroxytryptamine receptor 2A [Source:HGNC Symbol;Acc:HGNC:5293]",0,{"v":0.000723947368421053,"d":"0.00"},"-inf","-inf",1,1,"down","no"]
["ENSG00000187950","OVCH1","ENST00000318184","GO:0046872(metal ion binding);GO:0016787(hydrolase activity);GO:0008233(peptidase activity);GO:0006508(proteolysis);GO:0005576(extracellular region);GO:0004252(serine-type endopeptidase activity);GO:0008236(serine-type peptidase activity)","NA","NA","NA","ovochymase 1 [Source:HGNC Symbol;Acc:HGNC:23080]",{"v":0.00458960965133906,"d":"0.00"},0,"inf","inf",1,1,"up","no"]
["ENSG00000233471","KRT18P62","ENST00000446618","NA","NA","NA","NA","keratin 18 pseudogene 62 [Source:HGNC Symbol;Acc:HGNC:48889]",0,0,1,0,1,1,"no","no"]
["ENSG00000188760","TMEM198","ENST00000373883;ENST00000344458","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005886(plasma membrane);GO:0007275(multicellular organism development);GO:0016055(Wnt signaling pathway);GO:0031410(cytoplasmic vesicle);GO:0090263(positive regulation of canonical Wnt signaling pathway);GO:0090263(positive regulation of canonical Wnt signaling pathway)","NA","NA","NA","transmembrane protein 198 [Source:HGNC Symbol;Acc:HGNC:33704]",0,{"v":0.0196758809154383,"d":"0.02"},"-inf","-inf",1,1,"down","no"]
["ENSG00000157502","MUM1L1","ENST00000337685","GO:0070062(extracellular exosome)","NA","NA","NA","MUM1 like 1 [Source:HGNC Symbol;Acc:HGNC:26583]",0,0,1,0,1,1,"no","no"]
["ENSG00000160339","FCN2","ENST00000291744","GO:0046872(metal ion binding);GO:0030246(carbohydrate binding);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0005581(collagen trimer);GO:0006508(proteolysis);GO:0002376(immune system process);GO:0045087(innate immune response);GO:0003823(antigen binding);GO:0004252(serine-type endopeptidase activity);GO:0006956(complement activation);GO:0070062(extracellular exosome);GO:0050829(defense response to Gram-negative bacterium);GO:0072562(blood microparticle);GO:0048306(calcium-dependent protein binding);GO:0050830(defense response to Gram-positive bacterium);GO:0001867(complement activation, lectin pathway);GO:0043654(recognition of apoptotic cell);GO:0043394(proteoglycan binding);GO:2001065(mannan binding);GO:0008228(opsonization)","NA","NA","NA","ficolin 2 [Source:HGNC Symbol;Acc:HGNC:3624]",0,0,1,0,1,1,"no","no"]
["MSTRG.15416",null,"MSTRG.15416.1","NA","NA","NA","NA",null,{"v":4.174979,"d":"4.17"},{"v":0.90617,"d":"0.91"},{"v":4.60728009093217,"d":"4.61"},{"v":2.20391530654116,"d":"2.20"},1,1,"up","no"]
["MSTRG.6533","AC069366.1","ENST00000583159","NA","NA","NA","NA",null,{"v":0.189956,"d":"0.19"},0,"inf","inf",1,1,"up","no"]
["ENSG00000177294","FBXO39","ENST00000321535","GO:0019005(SCF ubiquitin ligase complex);GO:0031146(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)","NA","NA","NA","F-box protein 39 [Source:HGNC Symbol;Acc:HGNC:28565]",0,{"v":0.0174406850582591,"d":"0.02"},"-inf","-inf",1,1,"down","no"]
["MSTRG.9237","AC078883.2","ENST00000441212","NA","NA","NA","NA",null,0,{"v":0.091204,"d":"0.09"},"-inf","-inf",1,1,"down","no"]
["ENSG00000169059","VCX3A","ENST00000381089","GO:0005634(nucleus);GO:0005730(nucleolus);GO:0007420(brain development)","NA","NA","NA","variable charge, X-linked 3A [Source:HGNC Symbol;Acc:HGNC:18159]",0,0,1,0,1,1,"no","no"]
["MSTRG.10877","AC098613.1","ENST00000451485","NA","NA","NA","NA",null,{"v":0.747595,"d":"0.75"},{"v":0.537787,"d":"0.54"},{"v":1.39013215269242,"d":"1.39"},{"v":0.475222039043293,"d":"0.48"},1,1,"up","no"]
["MSTRG.3483","NDUFA4L2","ENST00000555173;ENST00000556732;ENST00000556234","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:1902600(hydrogen ion transmembrane transport);GO:0005751(mitochondrial respiratory chain complex IV);GO:0004129(cytochrome-c oxidase activity);GO:0004129(cytochrome-c oxidase activity)","00190(Oxidative phosphorylation);04723(Retrograde endocannabinoid signaling);05010(Alzheimer's disease);05012(Parkinson's disease);05016(Huntington's disease);04932(Non-alcoholic fatty liver disease (NAFLD));04932(Non-alcoholic fatty liver disease (NAFLD))","NA","NA","NDUFA4, mitochondrial complex associated like 2 [Source:HGNC Symbol;Acc:HGNC:29836]",{"v":0.0376734141126158,"d":"0.04"},0,"inf","inf",1,1,"up","no"]
["ENSG00000283680","AC135068.12","ENST00000637370","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000204335","SP5","ENST00000375281","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0000981(RNA polymerase II transcription factor activity, sequence-specific DNA binding);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0000977(RNA polymerase II regulatory region sequence-specific DNA binding);GO:0043565(sequence-specific DNA binding);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0036342(post-anal tail morphogenesis);GO:0060349(bone morphogenesis);GO:0071407(cellular response to organic cyclic compound)","NA","NA","NA","Sp5 transcription factor [Source:HGNC Symbol;Acc:HGNC:14529]",0,0,1,0,1,1,"no","no"]
["ENSG00000223658","C1GALT1C1L","ENST00000475092","GO:0016020(membrane);GO:0016021(integral component of membrane)","NA","NA","NA","C1GALT1-specific chaperone 1 like [Source:HGNC Symbol;Acc:HGNC:51617]",0,{"v":0.043423,"d":"0.04"},"-inf","-inf",1,1,"down","no"]
["ENSG00000267026","AL136084.2","ENST00000589257;ENST00000630758","NA","NA","NA","NA",null,{"v":0.00939168271243198,"d":"0.01"},{"v":4.74811636668062E-3,"d":"0.00"},{"v":1.97798073744297,"d":"1.98"},{"v":0.984028376485894,"d":"0.98"},1,1,"up","no"]
["ENSG00000258278","CLUHP8","ENST00000547527","NA","NA","NA","NA","clustered mitochondria homolog pseudogene 8 [Source:HGNC Symbol;Acc:HGNC:51573]",0,0,1,0,1,1,"no","no"]
["ENSG00000147180","ZNF711","ENST00000373165;ENST00000360700","GO:0005634(nucleus);GO:0003676(nucleic acid binding);GO:0046872(metal ion binding);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0045893(positive regulation of transcription, DNA-templated);GO:0005515(protein binding);GO:0070062(extracellular exosome);GO:0043565(sequence-specific DNA binding);GO:0043565(sequence-specific DNA binding)","NA","NA","NA","zinc finger protein 711 [Source:HGNC Symbol;Acc:HGNC:13128]",{"v":0.164363967226219,"d":"0.16"},{"v":0.123538456434852,"d":"0.12"},{"v":1.33046803375673,"d":"1.33"},{"v":0.411933848131907,"d":"0.41"},1,1,"up","no"]
["ENSG00000227256","MIS18A-AS1","ENST00000453549","NA","NA","NA","NA","MIS18A antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:40106]",{"v":0.065084,"d":"0.07"},{"v":0.01512,"d":"0.02"},{"v":4.30449735449735,"d":"4.30"},{"v":2.10584478082494,"d":"2.11"},1,1,"up","no"]
["MSTRG.481","AL512353.1","ENST00000414798;ENST00000425076","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000118004","COLEC11","ENST00000419002;ENST00000403096;ENST00000418971","GO:0030246(carbohydrate binding);GO:0005576(extracellular region);GO:0005581(collagen trimer);GO:0006508(proteolysis);GO:0007275(multicellular organism development);GO:0004252(serine-type endopeptidase activity);GO:0006898(receptor-mediated endocytosis);GO:0006956(complement activation);GO:0001867(complement activation, lectin pathway);GO:0005537(mannose binding);GO:0032502(developmental process);GO:0032502(developmental process)","04145(Phagosome);04145(Phagosome)","K10066","NA","collectin subfamily member 11 [Source:HGNC Symbol;Acc:HGNC:17213]",0,0,1,0,1,1,"no","no"]
["MSTRG.13175","AL022067.1","ENST00000602426","NA","NA","NA","NA",null,{"v":0.115842,"d":"0.12"},0,"inf","inf",1,1,"up","no"]
["ENSG00000272077","AC124045.1","ENST00000606008","NA","NA","NA","NA",null,0,{"v":0.155746,"d":"0.16"},"-inf","-inf",1,1,"down","no"]
["MSTRG.10945","U73169.1","ENST00000395152","NA","NA","NA","NA",null,0,{"v":0.27734,"d":"0.28"},"-inf","-inf",1,1,"down","no"]
["ENSG00000188101","ALOX15P2","ENST00000340858","NA","NA","NA","NA","arachidonate 15-lipoxygenase pseudogene 2 [Source:HGNC Symbol;Acc:HGNC:39027]",0,0,1,0,1,1,"no","no"]
["ENSG00000081800","SLC13A1","ENST00000439260;ENST00000194130","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005215(transporter activity);GO:0055085(transmembrane transport);GO:0015293(symporter activity);GO:0006811(ion transport);GO:0006814(sodium ion transport);GO:0035725(sodium ion transmembrane transport);GO:1902358(sulfate transmembrane transport);GO:0005886(plasma membrane);GO:0005887(integral component of plasma membrane);GO:0008271(secondary active sulfate transmembrane transporter activity);GO:0015382(sodium:sulfate symporter activity);GO:0008272(sulfate transport);GO:0008272(sulfate transport)","NA","NA","NA","solute carrier family 13 member 1 [Source:HGNC Symbol;Acc:HGNC:10916]",0,0,1,0,1,1,"no","no"]
["ENSG00000260977","AC016722.3","ENST00000568862","NA","NA","NA","NA",null,{"v":0.043134,"d":"0.04"},{"v":0.020799,"d":"0.02"},{"v":2.07384970431271,"d":"2.07"},{"v":1.05231134318701,"d":"1.05"},1,1,"up","no"]
["MSTRG.11409","AHSG","ENST00000411641","GO:0005615(extracellular space);GO:0005794(Golgi apparatus);GO:0010951(negative regulation of endopeptidase activity);GO:0005576(extracellular region);GO:0004869(cysteine-type endopeptidase inhibitor activity);GO:0070062(extracellular exosome);GO:0044267(cellular protein metabolic process);GO:0001501(skeletal system development);GO:0072562(blood microparticle);GO:0043687(post-translational protein modification);GO:0030500(regulation of bone mineralization);GO:0043312(neutrophil degranulation);GO:0006953(acute-phase response);GO:0002576(platelet degranulation);GO:0034774(secretory granule lumen);GO:0005788(endoplasmic reticulum lumen);GO:0031093(platelet alpha granule lumen);GO:0050766(positive regulation of phagocytosis);GO:0019210(kinase inhibitor activity);GO:0046627(negative regulation of insulin receptor signaling pathway);GO:0050727(regulation of inflammatory response);GO:0004866(endopeptidase inhibitor activity);GO:0001503(ossification);GO:0006907(pinocytosis);GO:0030502(negative regulation of bone mineralization);GO:0042326(negative regulation of phosphorylation);GO:0070168(negative regulation of biomineral tissue development);GO:0031012(extracellular matrix)","NA","NA","NA","alpha 2-HS glycoprotein [Source:HGNC Symbol;Acc:HGNC:349]",0,0,1,0,1,1,"no","no"]
["ENSG00000175741","RWDD4P2","ENST00000426392","NA","NA","NA","NA","RWD domain containing 4 pseudogene 2 [Source:HGNC Symbol;Acc:HGNC:23754]",0,0,1,0,1,1,"no","no"]
["MSTRG.5788","AC109460.4","ENST00000561471","NA","NA","NA","NA",null,0,{"v":0.000742,"d":"0.00"},"-inf","-inf",1,1,"down","no"]
["ENSG00000267060","PTGES3L","ENST00000462157;ENST00000591916;ENST00000464183;ENST00000409446","NA","NA","NA","NA","prostaglandin E synthase 3 like [Source:HGNC Symbol;Acc:HGNC:43943]",{"v":0.10469049894958,"d":"0.10"},{"v":0.013769119047619,"d":"0.01"},{"v":7.60328228607214,"d":"7.60"},{"v":2.92662235481742,"d":"2.93"},1,1,"up","no"]
["ENSG00000164588","HCN1","ENST00000303230","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0055085(transmembrane transport);GO:0000166(nucleotide binding);GO:0005216(ion channel activity);GO:0006811(ion transport);GO:0005887(integral component of plasma membrane);GO:0005244(voltage-gated ion channel activity);GO:0005249(voltage-gated potassium channel activity);GO:0005267(potassium channel activity);GO:0006813(potassium ion transport);GO:0034765(regulation of ion transmembrane transport);GO:0071805(potassium ion transmembrane transport);GO:0005886(plasma membrane);GO:0006814(sodium ion transport);GO:0030552(cAMP binding);GO:0005272(sodium channel activity);GO:0060078(regulation of postsynaptic membrane potential);GO:0035725(sodium ion transmembrane transport);GO:0051289(protein homotetramerization);GO:0071320(cellular response to cAMP);GO:0005222(intracellular cAMP activated cation channel activity);GO:0005248(voltage-gated sodium channel activity);GO:0022843(voltage-gated cation channel activity);GO:0042802(identical protein binding);GO:0042391(regulation of membrane potential);GO:0045176(apical protein localization);GO:0046549(retinal cone cell development);GO:0030424(axon);GO:0030425(dendrite);GO:0098855(HCN channel complex)","NA","NA","NA","hyperpolarization activated cyclic nucleotide gated potassium channel 1 [Source:HGNC Symbol;Acc:HGNC:4845]",0,0,1,0,1,1,"no","no"]
["ENSG00000260285","AL133367.1","ENST00000568177","NA","NA","NA","NA",null,0,{"v":0.012526,"d":"0.01"},"-inf","-inf",1,1,"down","no"]
["ENSG00000228205","AC131235.1","ENST00000433853","NA","NA","NA","NA",null,{"v":0.070886,"d":"0.07"},{"v":0.069524,"d":"0.07"},{"v":1.01959035728669,"d":"1.02"},{"v":0.0279896343373533,"d":"0.03"},1,1,"up","no"]
["ENSG00000272678","AC112503.1","ENST00000608436","NA","NA","NA","NA",null,0,{"v":0.130158,"d":"0.13"},"-inf","-inf",1,1,"down","no"]
["ENSG00000136457","CHAD","ENST00000506187;ENST00000508540;ENST00000258969","GO:0005576(extracellular region);GO:0005578(proteinaceous extracellular matrix);GO:0005737(cytoplasm);GO:0004860(protein kinase inhibitor activity);GO:0006469(negative regulation of protein kinase activity);GO:0019221(cytokine-mediated signaling pathway);GO:0046426(negative regulation of JAK-STAT cascade);GO:0060348(bone development);GO:1900155(negative regulation of bone trabecula formation);GO:1900155(negative regulation of bone trabecula formation)","04151(PI3K-Akt signaling pathway);04512(ECM-receptor interaction);04510(Focal adhesion);05165(Human papillomavirus infection);05165(Human papillomavirus infection)","K06248","NA","chondroadherin [Source:HGNC Symbol;Acc:HGNC:1909]",{"v":0.391535916204218,"d":"0.39"},{"v":0.190765502219756,"d":"0.19"},{"v":2.0524461270423,"d":"2.05"},{"v":1.03734435439337,"d":"1.04"},1,1,"up","no"]
["ENSG00000255299","AP003557.1","ENST00000531715;ENST00000527054","NA","NA","NA","NA",null,{"v":0.147692071856287,"d":"0.15"},0,"inf","inf",1,1,"up","no"]
["ENSG00000268163","AC004076.1","ENST00000415705;ENST00000596831","GO:0003676(nucleic acid binding);GO:0006355(regulation of transcription, DNA-templated);GO:0005622(intracellular);GO:0005622(intracellular)","NA","NA","NA",null,0,{"v":0.35727126459144,"d":"0.36"},"-inf","-inf",1,1,"down","no"]
["ENSG00000184350","MRGPRE","ENST00000389832","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0004930(G-protein coupled receptor activity);GO:0007186(G-protein coupled receptor signaling pathway);GO:0005886(plasma membrane);GO:0004871(signal transducer activity);GO:0007165(signal transduction);GO:0005887(integral component of plasma membrane);GO:1903955(positive regulation of protein targeting to mitochondrion)","NA","NA","NA","MAS related GPR family member E [Source:HGNC Symbol;Acc:HGNC:30694]",0,0,1,0,1,1,"no","no"]
["ENSG00000222033","LINC01124","ENST00000409786","NA","NA","NA","NA","long intergenic non-protein coding RNA 1124 [Source:HGNC Symbol;Acc:HGNC:49270]",0,0,1,0,1,1,"no","no"]
["ENSG00000167653","PSCA","ENST00000301258;ENST00000505305","GO:0016020(membrane);GO:0005886(plasma membrane);GO:0031225(anchored component of membrane);GO:0005576(extracellular region);GO:0070062(extracellular exosome);GO:0006501(C-terminal protein lipidation);GO:0070373(negative regulation of ERK1 and ERK2 cascade);GO:0033130(acetylcholine receptor binding);GO:0099601(regulation of neurotransmitter receptor activity);GO:0099601(regulation of neurotransmitter receptor activity)","NA","NA","NA","prostate stem cell antigen [Source:HGNC Symbol;Acc:HGNC:9500]",{"v":0.0301306131593874,"d":"0.03"},{"v":0.0120438684061259,"d":"0.01"},{"v":2.50173882206003,"d":"2.50"},{"v":1.32293118207496,"d":"1.32"},1,1,"up","no"]
["ENSG00000250745","USP17L20","ENST00000613757;ENST00000506151","GO:0005634(nucleus);GO:0016579(protein deubiquitination);GO:0016787(hydrolase activity);GO:0005783(endoplasmic reticulum);GO:0008233(peptidase activity);GO:0008234(cysteine-type peptidase activity);GO:0006508(proteolysis);GO:0006511(ubiquitin-dependent protein catabolic process);GO:0036459(thiol-dependent ubiquitinyl hydrolase activity);GO:0036459(thiol-dependent ubiquitinyl hydrolase activity)","NA","NA","NA","ubiquitin specific peptidase 17-like family member 20 [Source:HGNC Symbol;Acc:HGNC:44448]",0,0,1,0,1,1,"no","no"]
["ENSG00000255142","AP006621.2","ENST00000533938","NA","NA","NA","NA",null,{"v":0.329431,"d":"0.33"},{"v":0.232408,"d":"0.23"},{"v":1.41746841761041,"d":"1.42"},{"v":0.503316591065608,"d":"0.50"},1,1,"up","no"]
["ENSG00000275445","AC092119.3","ENST00000612618","NA","NA","NA","NA",null,{"v":0.182229,"d":"0.18"},{"v":0.087293,"d":"0.09"},{"v":2.08755570320644,"d":"2.09"},{"v":1.06181469419388,"d":"1.06"},1,1,"up","no"]
["ENSG00000143512","HHIPL2","ENST00000343410","GO:0003824(catalytic activity);GO:0005515(protein binding);GO:0005576(extracellular region)","NA","NA","NA","HHIP like 2 [Source:HGNC Symbol;Acc:HGNC:25842]",0,{"v":0.0307927409546975,"d":"0.03"},"-inf","-inf",1,1,"down","no"]
["ENSG00000132825","PPP1R3D","ENST00000370996","GO:0006470(protein dephosphorylation);GO:0005975(carbohydrate metabolic process);GO:0004722(protein serine/threonine phosphatase activity);GO:0005977(glycogen metabolic process);GO:0004721(phosphoprotein phosphatase activity);GO:0019899(enzyme binding);GO:0005979(regulation of glycogen biosynthetic process);GO:0005981(regulation of glycogen catabolic process);GO:0042587(glycogen granule);GO:0043231(intracellular membrane-bounded organelle)","04910(Insulin signaling pathway);04931(Insulin resistance)","K07189","NA","protein phosphatase 1 regulatory subunit 3D [Source:HGNC Symbol;Acc:HGNC:9294]",0,0,1,0,1,1,"no","no"]
["ENSG00000229311","BX088651.2","ENST00000425493","NA","NA","NA","NA",null,{"v":0.00668,"d":"0.01"},0,"inf","inf",1,1,"up","no"]
["MSTRG.5222","TIPIN;AC055855.1","ENST00000561773;ENST00000570251;ENST00000568216;ENST00000261881;ENST00000566524;ENST00000489563","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0043231(intracellular membrane-bounded organelle);GO:0051301(cell division);GO:0005515(protein binding);GO:0006974(cellular response to DNA damage stimulus);GO:0007049(cell cycle);GO:0005654(nucleoplasm);GO:0048478(replication fork protection);GO:0003677(DNA binding);GO:0006260(DNA replication);GO:0008284(positive regulation of cell proliferation);GO:0044770(cell cycle phase transition);GO:0031298(replication fork protection complex);GO:0000076(DNA replication checkpoint);GO:0000077(DNA damage checkpoint);GO:0009411(response to UV);GO:0031573(intra-S DNA damage checkpoint);GO:0033262(regulation of nuclear cell cycle DNA replication);GO:0043111(replication fork arrest);GO:0000790(nuclear chromatin);GO:0000790(nuclear chromatin)","NA","NA","NA","TIMELESS interacting protein [Source:HGNC Symbol;Acc:HGNC:30750]",{"v":0.204009479491833,"d":"0.20"},{"v":0.387066715063521,"d":"0.39"},{"v":0.527065416767632,"d":"0.53"},{"v":-0.923946061698039,"d":"-0.92"},1,1,"down","no"]
["ENSG00000253227","AC090192.2","ENST00000517482","NA","NA","NA","NA",null,{"v":0.082062,"d":"0.08"},0,"inf","inf",1,1,"up","no"]
["MSTRG.12815","MCCD1P2","ENST00000423228","NA","NA","NA","NA","mitochondrial coiled-coil domain 1 pseudogene 2 [Source:HGNC Symbol;Acc:HGNC:33462]",0,0,1,0,1,1,"no","no"]
["ENSG00000261202","Z83847.1","ENST00000569912","NA","NA","NA","NA",null,0,{"v":0.139144,"d":"0.14"},"-inf","-inf",1,1,"down","no"]
["ENSG00000236140","AC245014.1","ENST00000427732","NA","NA","NA","NA",null,{"v":0.167637,"d":"0.17"},{"v":0.429074,"d":"0.43"},{"v":0.390694845178221,"d":"0.39"},{"v":-1.35588587413639,"d":"-1.36"},1,1,"down","no"]
["ENSG00000224678","GAPDHP46","ENST00000424043","NA","NA","NA","NA","glyceraldehyde 3 phosphate dehydrogenase pseudogene 46 [Source:HGNC Symbol;Acc:HGNC:37804]",0,0,1,0,1,1,"no","no"]
["ENSG00000183150","GPR19","ENST00000332427;ENST00000540796;ENST00000540510;ENST00000545876;ENST00000537507","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0004930(G-protein coupled receptor activity);GO:0007186(G-protein coupled receptor signaling pathway);GO:0005886(plasma membrane);GO:0004871(signal transducer activity);GO:0007165(signal transduction);GO:0005887(integral component of plasma membrane);GO:0007268(chemical synaptic transmission);GO:0007631(feeding behavior);GO:0007218(neuropeptide signaling pathway);GO:0007218(neuropeptide signaling pathway)","NA","NA","NA","G protein-coupled receptor 19 [Source:HGNC Symbol;Acc:HGNC:4473]",{"v":0.266890797941289,"d":"0.27"},{"v":0.143625012581014,"d":"0.14"},{"v":1.85824734247278,"d":"1.86"},{"v":0.893942544782571,"d":"0.89"},1,1,"up","no"]
["ENSG00000174669","SLC29A2","ENST00000540386;ENST00000357440;ENST00000546034;ENST00000619145;ENST00000311161","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0006810(transport);GO:0005887(integral component of plasma membrane);GO:0005337(nucleoside transmembrane transporter activity);GO:1901642(nucleoside transmembrane transport);GO:0015858(nucleoside transport);GO:0005634(nucleus);GO:0005886(plasma membrane);GO:0016323(basolateral plasma membrane);GO:0006139(nucleobase-containing compound metabolic process);GO:0031965(nuclear membrane);GO:0008283(cell proliferation);GO:0005730(nucleolus);GO:0005730(nucleolus)","NA","NA","NA","solute carrier family 29 member 2 [Source:HGNC Symbol;Acc:HGNC:11004]",{"v":0.743822703676471,"d":"0.74"},{"v":0.208661105882353,"d":"0.21"},{"v":3.56474054199565,"d":"3.56"},{"v":1.83379707459394,"d":"1.83"},1,1,"up","no"]
["ENSG00000277501","AC243571.2","ENST00000615265","NA","NA","NA","NA",null,{"v":0.0270814246575342,"d":"0.03"},0,"inf","inf",1,1,"up","no"]
["MSTRG.8904","LINC01943","ENST00000625410;ENST00000628090","NA","NA","NA","NA","long intergenic non-protein coding RNA 1943 [Source:HGNC Symbol;Acc:HGNC:52767]",{"v":0.143457521355932,"d":"0.14"},{"v":0.158998831186441,"d":"0.16"},{"v":0.902255194490799,"d":"0.90"},{"v":-0.148392550813574,"d":"-0.15"},1,1,"down","no"]
["ENSG00000230266","XXYLT1-AS2","ENST00000426468;ENST00000447975","NA","NA","NA","NA","XXYLT1 antisense RNA 2 [Source:HGNC Symbol;Acc:HGNC:41154]",{"v":0.0188457448979592,"d":"0.02"},{"v":0.168945869897959,"d":"0.17"},{"v":0.111549012173791,"d":"0.11"},{"v":-3.16425035708552,"d":"-3.16"},1,1,"down","no"]
["MSTRG.12661","AL139095.4","ENST00000379928","NA","NA","NA","NA",null,{"v":0.125429,"d":"0.13"},{"v":0.017526,"d":"0.02"},{"v":7.15673855985393,"d":"7.16"},{"v":2.839302278063,"d":"2.84"},1,1,"up","no"]
["ENSG00000251637","AP003716.1","ENST00000529069;ENST00000533670;ENST00000511677","NA","NA","NA","NA",null,{"v":0.0736419414437153,"d":"0.07"},{"v":0.0249163553760727,"d":"0.02"},{"v":2.95556634717267,"d":"2.96"},{"v":1.56343460687289,"d":"1.56"},1,1,"up","no"]
["ENSG00000253552","HOXA-AS2","ENST00000517550;ENST00000523364;ENST00000517635","NA","NA","NA","NA","HOXA cluster antisense RNA 2 [Source:HGNC Symbol;Acc:HGNC:43745]",{"v":0.005029472637758,"d":"0.01"},{"v":0.0481521217572429,"d":"0.05"},{"v":0.104449657755766,"d":"0.10"},{"v":-3.25912032967112,"d":"-3.26"},1,1,"down","no"]
["ENSG00000147642","SYBU","ENST00000533065;ENST00000399066","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0043231(intracellular membrane-bounded organelle);GO:0005794(Golgi apparatus);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0000139(Golgi membrane);GO:0005874(microtubule);GO:0031410(cytoplasmic vesicle);GO:0019894(kinesin binding);GO:0017075(syntaxin-1 binding);GO:0031982(vesicle);GO:0008017(microtubule binding);GO:0061178(regulation of insulin secretion involved in cellular response to glucose stimulus);GO:0097433(dense body);GO:0097433(dense body)","NA","NA","NA","syntabulin [Source:HGNC Symbol;Acc:HGNC:26011]",0,{"v":0.0504300448462415,"d":"0.05"},"-inf","-inf",1,1,"down","no"]
["ENSG00000274628","AL669942.1","ENST00000618309;ENST00000620585","NA","NA","NA","NA",null,{"v":0.00335244377129875,"d":"0.00"},{"v":0.00321150018932223,"d":"0.00"},{"v":1.04388714733542,"d":"1.04"},{"v":0.0619657533063909,"d":"0.06"},1,1,"up","no"]
["MSTRG.8536","AC012065.2","ENST00000421295","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["MSTRG.324","AL353622.1","ENST00000604716","NA","NA","NA","NA",null,0,{"v":0.605531,"d":"0.61"},"-inf","-inf",1,1,"down","no"]
["ENSG00000251576","LINC01267","ENST00000502417","NA","NA","NA","NA","long intergenic non-protein coding RNA 1267 [Source:HGNC Symbol;Acc:HGNC:50320]",0,{"v":0.022282,"d":"0.02"},"-inf","-inf",1,1,"down","no"]
["ENSG00000255359","CCDC179","ENST00000532798","NA","NA","NA","NA","coiled-coil domain containing 179 [Source:HGNC Symbol;Acc:HGNC:44653]",0,0,1,0,1,1,"no","no"]
["ENSG00000005108","THSD7A","ENST00000423059","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005886(plasma membrane);GO:0005576(extracellular region);GO:0030154(cell differentiation);GO:0070062(extracellular exosome);GO:0001525(angiogenesis)","NA","NA","NA","thrombospondin type 1 domain containing 7A [Source:HGNC Symbol;Acc:HGNC:22207]",{"v":0.00486074352639766,"d":"0.00"},{"v":4.65683035959374E-3,"d":"0.00"},{"v":1.04378797402053,"d":"1.04"},{"v":0.0618286851886337,"d":"0.06"},1,1,"up","no"]
["ENSG00000258987","AL132642.1","ENST00000557646","NA","NA","NA","NA",null,{"v":0.069589,"d":"0.07"},0,"inf","inf",1,1,"up","no"]
["ENSG00000229646","AL109914.1","ENST00000414740","NA","NA","NA","NA",null,{"v":0.349377,"d":"0.35"},{"v":0.063482,"d":"0.06"},{"v":5.50356006427019,"d":"5.50"},{"v":2.46036515055189,"d":"2.46"},1,1,"up","no"]
["ENSG00000279742","AP000974.1","ENST00000623909","NA","NA","NA","NA",null,{"v":0.043402,"d":"0.04"},{"v":0.031981,"d":"0.03"},{"v":1.35711828898408,"d":"1.36"},{"v":0.440546474252133,"d":"0.44"},1,1,"up","no"]
["ENSG00000187498","COL4A1","ENST00000474391;ENST00000375820","GO:0005515(protein binding);GO:0005576(extracellular region);GO:0005581(collagen trimer);GO:0005578(proteinaceous extracellular matrix);GO:0005201(extracellular matrix structural constituent);GO:0005604(basement membrane);GO:0031012(extracellular matrix);GO:0030574(collagen catabolic process);GO:0005788(endoplasmic reticulum lumen);GO:0030198(extracellular matrix organization);GO:0001525(angiogenesis);GO:0001569(branching involved in blood vessel morphogenesis);GO:0061304(retinal blood vessel morphogenesis);GO:0048407(platelet-derived growth factor binding);GO:0030023(extracellular matrix constituent conferring elasticity);GO:0007420(brain development);GO:0007528(neuromuscular junction development);GO:0030855(epithelial cell differentiation);GO:0038063(collagen-activated tyrosine kinase receptor signaling pathway);GO:0048514(blood vessel morphogenesis);GO:0061333(renal tubule morphogenesis);GO:0071230(cellular response to amino acid stimulus);GO:0071711(basement membrane organization);GO:0005587(collagen type IV trimer);GO:0005615(extracellular space);GO:0005615(extracellular space)","04151(PI3K-Akt signaling pathway);04512(ECM-receptor interaction);04510(Focal adhesion);04926(Relaxin signaling pathway);04974(Protein digestion and absorption);05200(Pathways in cancer);05222(Small cell lung cancer);04933(AGE-RAGE signaling pathway in diabetic complications);05165(Human papillomavirus infection);05146(Amoebiasis);05146(Amoebiasis)","K06237","NA","collagen type IV alpha 1 chain [Source:HGNC Symbol;Acc:HGNC:2202]",{"v":0.0129754494382022,"d":"0.01"},0,"inf","inf",1,1,"up","no"]
["ENSG00000221989","OR2A2","ENST00000408979","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0004930(G-protein coupled receptor activity);GO:0007186(G-protein coupled receptor signaling pathway);GO:0005886(plasma membrane);GO:0004871(signal transducer activity);GO:0007165(signal transduction);GO:0004984(olfactory receptor activity);GO:0007608(sensory perception of smell);GO:0050896(response to stimulus);GO:0050911(detection of chemical stimulus involved in sensory perception of smell)","04740(Olfactory transduction)","K04257","NA","olfactory receptor family 2 subfamily A member 2 [Source:HGNC Symbol;Acc:HGNC:8230]",0,0,1,0,1,1,"no","no"]
["ENSG00000188185","LINC00265","ENST00000340510;ENST00000448955","NA","NA","NA","NA","long intergenic non-protein coding RNA 265 [Source:HGNC Symbol;Acc:HGNC:28019]",{"v":1.06579506548957,"d":"1.07"},{"v":0.184828128731942,"d":"0.18"},{"v":5.76641159980201,"d":"5.77"},{"v":2.52767381841448,"d":"2.53"},1,1,"up","no"]
["MSTRG.12504","AC009185.1","ENST00000517634","NA","NA","NA","NA",null,{"v":0.120741,"d":"0.12"},{"v":0.040714,"d":"0.04"},{"v":2.96558923220514,"d":"2.97"},{"v":1.56831878197983,"d":"1.57"},1,1,"up","no"]
["ENSG00000232046","LINC01798","ENST00000433396","NA","NA","NA","NA","long intergenic non-protein coding RNA 1798 [Source:HGNC Symbol;Acc:HGNC:52588]",{"v":0.0167741443683883,"d":"0.02"},0,"inf","inf",1,1,"up","no"]
["ENSG00000231513","E2F6P4","ENST00000468625","NA","NA","NA","NA","E2F transcription factor 6 pseudogene 4 [Source:HGNC Symbol;Acc:HGNC:51452]",0,0,1,0,1,1,"no","no"]
["MSTRG.6691","CCT6B","ENST00000436961;ENST00000314144;ENST00000421975;ENST00000577307;ENST00000585073","GO:0005737(cytoplasm);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0005829(cytosol);GO:0006457(protein folding);GO:0051082(unfolded protein binding);GO:0061077(chaperone-mediated protein folding);GO:0007283(spermatogenesis);GO:0051131(chaperone-mediated protein complex assembly);GO:0044183(protein binding involved in protein folding);GO:0006458('de novo' protein folding);GO:0005832(chaperonin-containing T-complex);GO:0015031(protein transport);GO:0008565(protein transporter activity);GO:1901998(toxin transport);GO:1901998(toxin transport)","NA","NA","NA","chaperonin containing TCP1 subunit 6B [Source:HGNC Symbol;Acc:HGNC:1621]",{"v":0.0608840982925704,"d":"0.06"},{"v":0.225463003922473,"d":"0.23"},{"v":0.270040304765503,"d":"0.27"},{"v":-1.88875334262715,"d":"-1.89"},1,1,"down","no"]
["ENSG00000205488","CALML3-AS1","ENST00000543008","NA","NA","NA","NA","CALML3 antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:44682]",{"v":0.0113146413706117,"d":"0.01"},0,"inf","inf",1,1,"up","no"]
["ENSG00000239388","ASB14","ENST00000487349","GO:0016567(protein ubiquitination);GO:0035556(intracellular signal transduction);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0004842(ubiquitin-protein transferase activity);GO:0031625(ubiquitin protein ligase binding);GO:0000151(ubiquitin ligase complex);GO:0005829(cytosol);GO:0043687(post-translational protein modification)","NA","NA","NA","ankyrin repeat and SOCS box containing 14 [Source:HGNC Symbol;Acc:HGNC:19766]",{"v":0.133345869740099,"d":"0.13"},{"v":0.0735753582920792,"d":"0.07"},{"v":1.81237132696987,"d":"1.81"},{"v":0.857878571661577,"d":"0.86"},1,1,"up","no"]
["MSTRG.3291","AC093012.1","ENST00000548437;ENST00000549403","NA","NA","NA","NA",null,{"v":0.0498201948717949,"d":"0.05"},{"v":0.0258523076923077,"d":"0.03"},{"v":1.92710822819964,"d":"1.93"},{"v":0.946437597011073,"d":"0.95"},1,1,"up","no"]
["ENSG00000253595","LINC01300","ENST00000521073","NA","NA","NA","NA","long intergenic non-protein coding RNA 1300 [Source:HGNC Symbol;Acc:HGNC:50460]",{"v":0.063469236453202,"d":"0.06"},0,"inf","inf",1,1,"up","no"]
["MSTRG.1921","AL133215.1","ENST00000447344","NA","NA","NA","NA",null,{"v":0.12748,"d":"0.13"},{"v":0.056665,"d":"0.06"},{"v":2.24971322685961,"d":"2.25"},{"v":1.16974111141768,"d":"1.17"},1,1,"up","no"]
["ENSG00000106689","LHX2","ENST00000373615","GO:0046872(metal ion binding);GO:0005634(nucleus);GO:0006355(regulation of transcription, DNA-templated);GO:0006366(transcription from RNA polymerase II promoter);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0043565(sequence-specific DNA binding);GO:0045893(positive regulation of transcription, DNA-templated);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:0001076(transcription factor activity, RNA polymerase II transcription factor binding);GO:0001077(transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0003682(chromatin binding);GO:0001843(neural tube closure);GO:0001942(hair follicle development);GO:0007399(nervous system development);GO:0007411(axon guidance);GO:0007420(brain development);GO:0007498(mesoderm development);GO:0009953(dorsal/ventral pattern formation);GO:0021537(telencephalon development);GO:0021772(olfactory bulb development);GO:0021978(telencephalon regionalization);GO:0021987(cerebral cortex development);GO:0022008(neurogenesis);GO:0030182(neuron differentiation);GO:0045199(maintenance of epithelial cell apical/basal polarity);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0048646(anatomical structure formation involved in morphogenesis);GO:0048675(axon extension);GO:0060041(retina development in camera-type eye);GO:2000678(negative regulation of transcription regulatory region DNA binding);GO:0005622(intracellular)","NA","NA","NA","LIM homeobox 2 [Source:HGNC Symbol;Acc:HGNC:6594]",0,0,1,0,1,1,"no","no"]
["ENSG00000265752","AC010754.1","ENST00000582300","NA","NA","NA","NA",null,0,{"v":0.095296,"d":"0.10"},"-inf","-inf",1,1,"down","no"]
["ENSG00000182824","LINC01662","ENST00000342888","NA","NA","NA","NA","long intergenic non-protein coding RNA 1662 [Source:HGNC Symbol;Acc:HGNC:52450]",0,0,1,0,1,1,"no","no"]
["MSTRG.6022","AC027682.7","ENST00000623147","NA","NA","NA","NA",null,0,{"v":0.020816,"d":"0.02"},"-inf","-inf",1,1,"down","no"]
["ENSG00000276529","AP001505.2","ENST00000616815","NA","NA","NA","NA",null,0,{"v":0.457237,"d":"0.46"},"-inf","-inf",1,1,"down","no"]
["ENSG00000182632","CCNYL2","ENST00000637719;ENST00000472090","NA","NA","NA","NA","cyclin Y-like 2 (pseudogene) [Source:HGNC Symbol;Acc:HGNC:23495]",0,0,1,0,1,1,"no","no"]
["ENSG00000122543","OCM","ENST00000242104;ENST00000416608","GO:0046872(metal ion binding);GO:0005509(calcium ion binding);GO:0005509(calcium ion binding)","NA","NA","NA","oncomodulin [Source:HGNC Symbol;Acc:HGNC:8105]",{"v":0.324645150240385,"d":"0.32"},{"v":0.145498205528846,"d":"0.15"},{"v":2.23126566448286,"d":"2.23"},{"v":1.1578622975417,"d":"1.16"},1,1,"up","no"]
["ENSG00000276770","MIR6780B","ENST00000610307","NA","NA","NA","NA","microRNA 6780b [Source:HGNC Symbol;Acc:HGNC:50237]",{"v":0.233858,"d":"0.23"},0,"inf","inf",1,1,"up","no"]
["ENSG00000284237","AL356275.1","ENST00000638446","NA","NA","NA","NA",null,0,{"v":0.003194,"d":"0.00"},"-inf","-inf",1,1,"down","no"]
["ENSG00000255434","AP001922.6","ENST00000532553","NA","NA","NA","NA",null,0,{"v":0.033074,"d":"0.03"},"-inf","-inf",1,1,"down","no"]
["ENSG00000134042","MRO","ENST00000256425;ENST00000590988","GO:0005634(nucleus);GO:0005730(nucleolus);GO:0005730(nucleolus)","NA","NA","NA","maestro [Source:HGNC Symbol;Acc:HGNC:24121]",0,0,1,0,1,1,"no","no"]
["ENSG00000253495","CYCSP23","ENST00000519781","NA","NA","NA","NA","cytochrome c, somatic pseudogene 23 [Source:HGNC Symbol;Acc:HGNC:24397]",0,0,1,0,1,1,"no","no"]
["ENSG00000267130","AC008738.2","ENST00000593041","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000134240","HMGCS2","ENST00000472375;ENST00000369406","GO:0016740(transferase activity);GO:0005739(mitochondrion);GO:0003824(catalytic activity);GO:0006629(lipid metabolic process);GO:0008152(metabolic process);GO:0004421(hydroxymethylglutaryl-CoA synthase activity);GO:0006694(steroid biosynthetic process);GO:0008202(steroid metabolic process);GO:0008299(isoprenoid biosynthetic process);GO:0016126(sterol biosynthetic process);GO:0008203(cholesterol metabolic process);GO:0005743(mitochondrial inner membrane);GO:0006695(cholesterol biosynthetic process);GO:0005759(mitochondrial matrix);GO:0019216(regulation of lipid metabolic process);GO:0046951(ketone body biosynthetic process);GO:0046951(ketone body biosynthetic process)","00650(Butanoate metabolism);00072(Synthesis and degradation of ketone bodies);00280(Valine, leucine and isoleucine degradation);00900(Terpenoid backbone biosynthesis);03320(PPAR signaling pathway);03320(PPAR signaling pathway)","K01641","EC:2.3.3.10","3-hydroxy-3-methylglutaryl-CoA synthase 2 [Source:HGNC Symbol;Acc:HGNC:5008]",0,0,1,0,1,1,"no","no"]
["ENSG00000254737","OR10G4","ENST00000320891","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0004930(G-protein coupled receptor activity);GO:0007186(G-protein coupled receptor signaling pathway);GO:0005886(plasma membrane);GO:0004871(signal transducer activity);GO:0007165(signal transduction);GO:0004984(olfactory receptor activity);GO:0007608(sensory perception of smell);GO:0050896(response to stimulus);GO:0050911(detection of chemical stimulus involved in sensory perception of smell)","04740(Olfactory transduction)","K04257","NA","olfactory receptor family 10 subfamily G member 4 [Source:HGNC Symbol;Acc:HGNC:14809]",0,0,1,0,1,1,"no","no"]
["ENSG00000235268","KDM4E","ENST00000450979","GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0016569(covalent chromatin modification);GO:0051213(dioxygenase activity);GO:0032454(histone demethylase activity (H3-K9 specific));GO:0033169(histone H3-K9 demethylation)","NA","NA","NA","lysine demethylase 4E [Source:HGNC Symbol;Acc:HGNC:37098]",{"v":0.045421,"d":"0.05"},0,"inf","inf",1,1,"up","no"]
["MSTRG.13700","PHBP5","ENST00000449310","NA","NA","NA","NA","prohibitin pseudogene 5 [Source:HGNC Symbol;Acc:HGNC:39284]",0,{"v":0.066265,"d":"0.07"},"-inf","-inf",1,1,"down","no"]
["ENSG00000267881","AC243967.1","ENST00000435837;ENST00000598976","NA","NA","NA","NA",null,{"v":0.000368301675977654,"d":"0.00"},{"v":8.0023938547486E-3,"d":"0.01"},{"v":0.0460239376694893,"d":"0.05"},{"v":-4.44147176828966,"d":"-4.44"},1,1,"down","no"]
["MSTRG.11589","AC098869.2","ENST00000514187","NA","NA","NA","NA",null,{"v":0.324301,"d":"0.32"},{"v":0.058648,"d":"0.06"},{"v":5.52961737825672,"d":"5.53"},{"v":2.46717965666447,"d":"2.47"},1,1,"up","no"]
["ENSG00000254818","AP004607.3","ENST00000530354","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["MSTRG.4868","TJP1","ENST00000495972;ENST00000558447;ENST00000561307;ENST00000346128","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0030054(cell junction);GO:0005515(protein binding);GO:0005921(gap junction);GO:0005923(bicellular tight junction);GO:0005516(calmodulin binding);GO:0045296(cadherin binding);GO:2000810(regulation of bicellular tight junction assembly);GO:0035329(hippo signaling);GO:0016323(basolateral plasma membrane);GO:0007043(cell-cell junction assembly);GO:0090557(establishment of endothelial intestinal barrier);GO:1901350(cell-cell signaling involved in cell-cell junction organization);GO:0005913(cell-cell adherens junction);GO:0043296(apical junction complex);GO:0045177(apical part of cell);GO:0008022(protein C-terminus binding);GO:0019904(protein domain specific binding);GO:0071253(connexin binding);GO:0001825(blastocyst formation);GO:0007605(sensory perception of sound);GO:0032496(response to lipopolysaccharide);GO:0042493(response to drug);GO:0043116(negative regulation of vascular permeability);GO:0045471(response to ethanol);GO:0071000(response to magnetism);GO:0071333(cellular response to glucose stimulus);GO:0005634(nucleus);GO:0005911(cell-cell junction);GO:0005912(adherens junction);GO:0014704(intercalated disc);GO:0016324(apical plasma membrane);GO:0016327(apicolateral plasma membrane);GO:0043234(protein complex);GO:0046581(intercellular canaliculus);GO:0070160(occluding junction);GO:0070160(occluding junction)","04520(Adherens junction);04530(Tight junction);04540(Gap junction);05110(Vibrio cholerae infection);05120(Epithelial cell signaling in Helicobacter pylori infection);05132(Salmonella infection);05132(Salmonella infection)","K05701","NA","tight junction protein 1 [Source:HGNC Symbol;Acc:HGNC:11827]",0,0,1,0,1,1,"no","no"]
["ENSG00000176399","DMRTA1","ENST00000325870","GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0043565(sequence-specific DNA binding);GO:0042803(protein homodimerization activity);GO:0001541(ovarian follicle development);GO:0060179(male mating behavior)","NA","NA","NA","DMRT like family A1 [Source:HGNC Symbol;Acc:HGNC:13826]",0,0,1,0,1,1,"no","no"]
["ENSG00000182898","TCHHL1","ENST00000368806","GO:0046914(transition metal ion binding)","NA","NA","NA","trichohyalin like 1 [Source:HGNC Symbol;Acc:HGNC:31796]",0,0,1,0,1,1,"no","no"]
["ENSG00000237400","AC006960.2","ENST00000435254","NA","NA","NA","NA",null,{"v":0.179047,"d":"0.18"},0,"inf","inf",1,1,"up","no"]
["ENSG00000236849","LINC01474","ENST00000449235","NA","NA","NA","NA","long intergenic non-protein coding RNA 1474 [Source:HGNC Symbol;Acc:HGNC:51111]",0,{"v":0.0042190985915493,"d":"0.00"},"-inf","-inf",1,1,"down","no"]
["ENSG00000107518","ATRNL1","ENST00000616894;ENST00000355044","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0030246(carbohydrate binding);GO:0007186(G-protein coupled receptor signaling pathway);GO:0007186(G-protein coupled receptor signaling pathway)","NA","NA","NA","attractin like 1 [Source:HGNC Symbol;Acc:HGNC:29063]",0,0,1,0,1,1,"no","no"]
["ENSG00000224905","AP001347.1","ENST00000428809","NA","NA","NA","NA",null,0,{"v":0.0161811661016949,"d":"0.02"},"-inf","-inf",1,1,"down","no"]
["ENSG00000262185","AC005736.1","ENST00000576810","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["MSTRG.5748","AC130448.1","ENST00000624179","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000145692","BHMT","ENST00000274353","GO:0005737(cytoplasm);GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0005829(cytosol);GO:0008168(methyltransferase activity);GO:0016740(transferase activity);GO:0032259(methylation);GO:0047150(betaine-homocysteine S-methyltransferase activity);GO:0009086(methionine biosynthetic process);GO:0070062(extracellular exosome);GO:0000096(sulfur amino acid metabolic process);GO:0042426(choline catabolic process);GO:0006479(protein methylation);GO:0006577(amino-acid betaine metabolic process);GO:0006579(amino-acid betaine catabolic process);GO:0050666(regulation of homocysteine metabolic process);GO:0071267(L-methionine salvage)","00260(Glycine, serine and threonine metabolism);00270(Cysteine and methionine metabolism)","K00544","EC:2.1.1.5","betaine--homocysteine S-methyltransferase [Source:HGNC Symbol;Acc:HGNC:1047]",0,0,1,0,1,1,"no","no"]
["ENSG00000250771","AC106865.1","ENST00000507055;ENST00000602666","NA","NA","NA","NA",null,{"v":0.00368764784864205,"d":"0.00"},{"v":0.0177151528837351,"d":"0.02"},{"v":0.208163478624438,"d":"0.21"},{"v":-2.26421111860923,"d":"-2.26"},1,1,"down","no"]
["ENSG00000240859","AC093627.4","ENST00000492208;ENST00000484550;ENST00000471299","NA","NA","NA","NA",null,{"v":0.360873620508837,"d":"0.36"},{"v":0.0233675560302971,"d":"0.02"},{"v":15.4433617294401,"d":"15.44"},{"v":3.94891492926034,"d":"3.95"},1,1,"up","no"]
["ENSG00000255581","AC006511.2","ENST00000388966","NA","NA","NA","NA",null,{"v":0.080485,"d":"0.08"},0,"inf","inf",1,1,"up","no"]
["ENSG00000229587","AL158825.2","ENST00000455336","NA","NA","NA","NA",null,{"v":0.087947,"d":"0.09"},0,"inf","inf",1,1,"up","no"]
["ENSG00000267423","AC005616.1","ENST00000592931","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000175664","TEX26","ENST00000380473","NA","NA","NA","NA","testis expressed 26 [Source:HGNC Symbol;Acc:HGNC:28622]",0,0,1,0,1,1,"no","no"]
["ENSG00000226149","AL356124.1","ENST00000419061","NA","NA","NA","NA",null,{"v":0.116832719907407,"d":"0.12"},0,"inf","inf",1,1,"up","no"]
["ENSG00000144229","THSD7B","ENST00000409968","GO:0016020(membrane);GO:0016021(integral component of membrane)","NA","NA","NA","thrombospondin type 1 domain containing 7B [Source:HGNC Symbol;Acc:HGNC:29348]",0,0,1,0,1,1,"no","no"]
["ENSG00000257074","RPL29P33","ENST00000587474","NA","NA","NA","NA","ribosomal protein L29 pseudogene 33 [Source:HGNC Symbol;Acc:HGNC:36923]",0,{"v":0.158917,"d":"0.16"},"-inf","-inf",1,1,"down","no"]
["ENSG00000196338","NLGN3","ENST00000374051;ENST00000358741","GO:0007155(cell adhesion);GO:0005887(integral component of plasma membrane);GO:0042043(neurexin family protein binding);GO:0050808(synapse organization);GO:0045202(synapse);GO:0050804(modulation of synaptic transmission);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005886(plasma membrane);GO:0030054(cell junction);GO:0005515(protein binding);GO:0009986(cell surface);GO:0048488(synaptic vesicle endocytosis);GO:0052689(carboxylic ester hydrolase activity);GO:0051965(positive regulation of synapse assembly);GO:0097110(scaffold protein binding);GO:0004872(receptor activity);GO:0035176(social behavior);GO:0030139(endocytic vesicle);GO:0006898(receptor-mediated endocytosis);GO:0050839(cell adhesion molecule binding);GO:0007612(learning);GO:0007416(synapse assembly);GO:0051968(positive regulation of synaptic transmission, glutamatergic);GO:0060080(inhibitory postsynaptic potential);GO:0097105(presynaptic membrane assembly);GO:0007158(neuron cell-cell adhesion);GO:0030534(adult behavior);GO:0071625(vocalization behavior);GO:0097104(postsynaptic membrane assembly);GO:2000463(positive regulation of excitatory postsynaptic potential);GO:0060024(rhythmic synaptic transmission);GO:0060076(excitatory synapse);GO:2000969(positive regulation of AMPA receptor activity);GO:0099055(integral component of postsynaptic membrane);GO:0002087(regulation of respiratory gaseous exchange by neurological system process);GO:0048675(axon extension);GO:0098794(postsynapse);GO:0008542(visual learning);GO:0048709(oligodendrocyte differentiation);GO:0051966(regulation of synaptic transmission, glutamatergic);GO:0060079(excitatory postsynaptic potential);GO:0060291(long-term synaptic potentiation);GO:0061001(regulation of dendritic spine morphogenesis);GO:0061002(negative regulation of dendritic spine morphogenesis);GO:0090394(negative regulation of excitatory postsynaptic potential);GO:1900271(regulation of long-term synaptic potentiation);GO:2000310(regulation of NMDA receptor activity);GO:2000311(regulation of AMPA receptor activity);GO:2000331(regulation of terminal button organization);GO:2000809(positive regulation of synaptic vesicle clustering);GO:2000809(positive regulation of synaptic vesicle clustering)","04514(Cell adhesion molecules (CAMs));04514(Cell adhesion molecules (CAMs))","K07378","NA","neuroligin 3 [Source:HGNC Symbol;Acc:HGNC:14289]",{"v":0.719425070644034,"d":"0.72"},{"v":0.175002722416375,"d":"0.18"},{"v":4.11093645121899,"d":"4.11"},{"v":2.0394670702186,"d":"2.04"},1,1,"up","no"]
["ENSG00000259341","AC015660.1","ENST00000560103","NA","NA","NA","NA",null,{"v":0.0521,"d":"0.05"},0,"inf","inf",1,1,"up","no"]
["ENSG00000233121","VN1R20P","ENST00000425215","NA","NA","NA","NA","vomeronasal 1 receptor 20 pseudogene [Source:HGNC Symbol;Acc:HGNC:37335]",{"v":0.109979,"d":"0.11"},{"v":0.105366,"d":"0.11"},{"v":1.04378072623047,"d":"1.04"},{"v":0.0618186674576954,"d":"0.06"},1,1,"up","no"]
["ENSG00000177689","MAGEB10","ENST00000614159","NA","NA","NA","NA","MAGE family member B10 [Source:HGNC Symbol;Acc:HGNC:25377]",0,0,1,0,1,1,"no","no"]
["ENSG00000154537","FAM27C","ENST00000377542","NA","NA","NA","NA","family with sequence similarity 27 member C [Source:HGNC Symbol;Acc:HGNC:23668]",{"v":0.086233,"d":"0.09"},0,"inf","inf",1,1,"up","no"]
["ENSG00000236111","AL603882.1","ENST00000463059","NA","NA","NA","NA",null,{"v":0.039001,"d":"0.04"},0,"inf","inf",1,1,"up","no"]
["MSTRG.5702","AF001548.1","ENST00000577048","NA","NA","NA","NA",null,0,{"v":0.03628,"d":"0.04"},"-inf","-inf",1,1,"down","no"]
["ENSG00000182315","MBD3L3","ENST00000333843","GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0005634(nucleus);GO:0008327(methyl-CpG binding);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0006346(methylation-dependent chromatin silencing)","NA","NA","NA","methyl-CpG binding domain protein 3 like 3 [Source:HGNC Symbol;Acc:HGNC:37205]",0,0,1,0,1,1,"no","no"]
["ENSG00000174109","C16orf91","ENST00000563974;ENST00000442039","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016021(integral component of membrane)","NA","NA","NA","chromosome 16 open reading frame 91 [Source:HGNC Symbol;Acc:HGNC:27558]",{"v":2.69219261494797,"d":"2.69"},{"v":0.131050288552507,"d":"0.13"},{"v":20.5432024964165,"d":"20.54"},{"v":4.36058919696969,"d":"4.36"},1,1,"up","no"]
["ENSG00000007001","UPP2","ENST00000605860","GO:0005737(cytoplasm);GO:0016740(transferase activity);GO:0009116(nucleoside metabolic process);GO:0003824(catalytic activity);GO:0016757(transferase activity, transferring glycosyl groups);GO:0005829(cytosol);GO:0005515(protein binding);GO:0044206(UMP salvage);GO:0004850(uridine phosphorylase activity);GO:0016763(transferase activity, transferring pentosyl groups);GO:0009166(nucleotide catabolic process);GO:0043097(pyrimidine nucleoside salvage);GO:0046108(uridine metabolic process);GO:0046135(pyrimidine nucleoside catabolic process);GO:0045098(type III intermediate filament)","00240(Pyrimidine metabolism);00983(Drug metabolism - other enzymes)","K00757","EC:2.4.2.3","uridine phosphorylase 2 [Source:HGNC Symbol;Acc:HGNC:23061]",0,0,1,0,1,1,"no","no"]
["ENSG00000234322","ST13P18","ENST00000456632","NA","NA","NA","NA","ST13, Hsp70 interacting protein pseudogene 18 [Source:HGNC Symbol;Acc:HGNC:38861]",{"v":0.051723,"d":"0.05"},{"v":0.074167,"d":"0.07"},{"v":0.697385629727507,"d":"0.70"},{"v":-0.519971458525055,"d":"-0.52"},1,1,"down","no"]
["MSTRG.13591","TRGV9","ENST00000444775","GO:0005887(integral component of plasma membrane);GO:0042605(peptide antigen binding);GO:0042287(MHC protein binding)","NA","NA","NA","T-cell receptor gamma variable 9 [Source:HGNC Symbol;Acc:HGNC:12295]",0,{"v":1.741105,"d":"1.74"},"-inf","-inf",1,1,"down","no"]
["ENSG00000272823","AL445423.1","ENST00000609941","NA","NA","NA","NA",null,{"v":0.198208,"d":"0.20"},0,"inf","inf",1,1,"up","no"]
["MSTRG.15109","CCDC183-AS1","ENST00000414656","NA","NA","NA","NA","CCDC183 antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:44105]",{"v":0.205849,"d":"0.21"},{"v":0.084399,"d":"0.08"},{"v":2.43899809239446,"d":"2.44"},{"v":1.28628862976422,"d":"1.29"},1,1,"up","no"]
["ENSG00000173227","SYT12","ENST00000531392;ENST00000393946","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0030054(cell junction);GO:0045202(synapse);GO:0031410(cytoplasmic vesicle);GO:0005886(plasma membrane);GO:0005509(calcium ion binding);GO:0005544(calcium-dependent phospholipid binding);GO:0019905(syntaxin binding);GO:0030276(clathrin binding);GO:0006906(vesicle fusion);GO:0017158(regulation of calcium ion-dependent exocytosis);GO:0048791(calcium ion-regulated exocytosis of neurotransmitter);GO:0046928(regulation of neurotransmitter secretion);GO:0060291(long-term synaptic potentiation);GO:0030672(synaptic vesicle membrane);GO:0048792(spontaneous exocytosis of neurotransmitter);GO:0048792(spontaneous exocytosis of neurotransmitter)","NA","NA","NA","synaptotagmin 12 [Source:HGNC Symbol;Acc:HGNC:18381]",0,0,1,0,1,1,"no","no"]
["ENSG00000229405","AC092580.1","ENST00000433998","NA","NA","NA","NA",null,0,{"v":0.077343,"d":"0.08"},"-inf","-inf",1,1,"down","no"]
["ENSG00000185960","SHOX","ENST00000381578","GO:0005634(nucleus);GO:0043231(intracellular membrane-bounded organelle);GO:0005654(nucleoplasm);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0043565(sequence-specific DNA binding);GO:0005515(protein binding);GO:0007275(multicellular organism development);GO:0001228(transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0006366(transcription from RNA polymerase II promoter);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0001501(skeletal system development)","NA","NA","NA","short stature homeobox [Source:HGNC Symbol;Acc:HGNC:10853]",0,0,1,0,1,1,"no","no"]
["ENSG00000239626","RPSAP41","ENST00000439695","NA","NA","NA","NA","ribosomal protein SA pseudogene 41 [Source:HGNC Symbol;Acc:HGNC:36663]",0,{"v":0.058687,"d":"0.06"},"-inf","-inf",1,1,"down","no"]
["ENSG00000276368","HIST1H2AJ","ENST00000333151","GO:0005634(nucleus);GO:0003677(DNA binding);GO:0046982(protein heterodimerization activity);GO:0000786(nucleosome);GO:0005694(chromosome);GO:0000790(nuclear chromatin);GO:0003674(molecular_function);GO:0008150(biological_process);GO:0070062(extracellular exosome);GO:0006342(chromatin silencing)","04217(Necroptosis);05322(Systemic lupus erythematosus);05034(Alcoholism)","K11251","NA","histone cluster 1 H2A family member j [Source:HGNC Symbol;Acc:HGNC:4727]",{"v":0.13726,"d":"0.14"},0,"inf","inf",1,1,"up","no"]
["ENSG00000237872","POU5F1P4","ENST00000413175","NA","NA","NA","NA","POU class 5 homeobox 1 pseudogene 4 [Source:HGNC Symbol;Acc:HGNC:33310]",0,0,1,0,1,1,"no","no"]
["ENSG00000250274","AC034199.1","ENST00000511921","NA","NA","NA","NA",null,{"v":0.207814,"d":"0.21"},{"v":0.209834,"d":"0.21"},{"v":0.990373342737593,"d":"0.99"},{"v":-0.0139556119364098,"d":"-0.01"},1,1,"down","no"]
["ENSG00000279324","AL645730.1","ENST00000622945","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000233041","PHGR1","ENST00000448599;ENST00000560745","NA","NA","NA","NA","proline, histidine and glycine rich 1 [Source:HGNC Symbol;Acc:HGNC:37226]",{"v":0.169350954303932,"d":"0.17"},0,"inf","inf",1,1,"up","no"]
["MSTRG.2514","AP003774.4","ENST00000447028","NA","NA","NA","NA",null,{"v":0.237142,"d":"0.24"},{"v":0.151464,"d":"0.15"},{"v":1.56566576876353,"d":"1.57"},{"v":0.646776265494876,"d":"0.65"},1,1,"up","no"]
["ENSG00000266486","FAM106CP","ENST00000582212","NA","NA","NA","NA","family with sequence similarity 106 member C, pseudogene [Source:HGNC Symbol;Acc:HGNC:38396]",0,0,1,0,1,1,"no","no"]
["ENSG00000232060","SLC4A1APP1","ENST00000419995","NA","NA","NA","NA","solute carrier family 4 member 1 adaptor protein pseudogene 1 [Source:HGNC Symbol;Acc:HGNC:49811]",{"v":0.085317,"d":"0.09"},{"v":0.040869,"d":"0.04"},{"v":2.08757248770462,"d":"2.09"},{"v":1.0618262937957,"d":"1.06"},1,1,"up","no"]
["ENSG00000259490","IGHV3OR15-7","ENST00000558565","GO:0003823(antigen binding);GO:0034987(immunoglobulin receptor binding);GO:0006910(phagocytosis, recognition);GO:0006911(phagocytosis, engulfment);GO:0006958(complement activation, classical pathway);GO:0042742(defense response to bacterium);GO:0045087(innate immune response);GO:0050853(B cell receptor signaling pathway);GO:0050871(positive regulation of B cell activation);GO:0009897(external side of plasma membrane);GO:0042571(immunoglobulin complex, circulating);GO:0072562(blood microparticle)","NA","NA","NA","immunoglobulin heavy variable 3/OR15-7 (pseudogene) [Source:HGNC Symbol;Acc:HGNC:5633]",0,0,1,0,1,1,"no","no"]
["ENSG00000224376","AC017104.1","ENST00000415129;ENST00000454416;ENST00000418050","NA","NA","NA","NA",null,{"v":0.299359487163431,"d":"0.30"},{"v":0.3183548816531,"d":"0.32"},{"v":0.940332642643854,"d":"0.94"},{"v":-0.0887568944800383,"d":"-0.09"},1,1,"down","no"]
["ENSG00000130224","LRCH2","ENST00000317135","GO:0005886(plasma membrane);GO:0007165(signal transduction)","NA","NA","NA","leucine rich repeats and calponin homology domain containing 2 [Source:HGNC Symbol;Acc:HGNC:29292]",0,0,1,0,1,1,"no","no"]
["ENSG00000226933","NRBF2P2","ENST00000413087","NA","NA","NA","NA","nuclear receptor binding factor 2 pseudogene 2 [Source:HGNC Symbol;Acc:HGNC:44605]",{"v":0.061695,"d":"0.06"},0,"inf","inf",1,1,"up","no"]
["ENSG00000137080","IFNA21","ENST00000380225","GO:0005576(extracellular region);GO:0005125(cytokine activity);GO:0005615(extracellular space);GO:0006952(defense response);GO:0045087(innate immune response);GO:0005126(cytokine receptor binding);GO:0051607(defense response to virus);GO:0019221(cytokine-mediated signaling pathway);GO:0060337(type I interferon signaling pathway);GO:0007596(blood coagulation);GO:0002250(adaptive immune response);GO:0005132(type I interferon receptor binding);GO:0002286(T cell activation involved in immune response);GO:0002323(natural killer cell activation involved in immune response);GO:0006959(humoral immune response);GO:0030183(B cell differentiation);GO:0033141(positive regulation of peptidyl-serine phosphorylation of STAT protein);GO:0042100(B cell proliferation);GO:0043330(response to exogenous dsRNA);GO:0060338(regulation of type I interferon-mediated signaling pathway)","04630(Jak-STAT signaling pathway);04151(PI3K-Akt signaling pathway);04060(Cytokine-cytokine receptor interaction);04217(Necroptosis);04620(Toll-like receptor signaling pathway);04621(NOD-like receptor signaling pathway);04622(RIG-I-like receptor signaling pathway);04623(Cytosolic DNA-sensing pathway);04650(Natural killer cell mediated cytotoxicity);05200(Pathways in cancer);05320(Autoimmune thyroid disease);05152(Tuberculosis);05162(Measles);05164(Influenza A);05161(Hepatitis B);05160(Hepatitis C);05168(Herpes simplex infection);05167(Kaposi's sarcoma-associated herpesvirus infection);05165(Human papillomavirus infection)","K05414","NA","interferon alpha 21 [Source:HGNC Symbol;Acc:HGNC:5424]",0,0,1,0,1,1,"no","no"]
["MSTRG.9222","SPC25","ENST00000479309;ENST00000282074","GO:0005634(nucleus);GO:0051301(cell division);GO:0005694(chromosome);GO:0005515(protein binding);GO:0007049(cell cycle);GO:0007059(chromosome segregation);GO:0000775(chromosome, centromeric region);GO:0000776(kinetochore);GO:0000777(condensed chromosome kinetochore);GO:0005829(cytosol);GO:0007052(mitotic spindle organization);GO:0007062(sister chromatid cohesion);GO:0031262(Ndc80 complex);GO:0031262(Ndc80 complex)","NA","NA","NA","SPC25, NDC80 kinetochore complex component [Source:HGNC Symbol;Acc:HGNC:24031]",{"v":0.0288539532862575,"d":"0.03"},{"v":0.16586169038566,"d":"0.17"},{"v":0.173963940794083,"d":"0.17"},{"v":-2.5231397993236,"d":"-2.52"},1,1,"down","no"]
["ENSG00000168955","TM4SF20","ENST00000304568","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005886(plasma membrane);GO:0005925(focal adhesion);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0045861(negative regulation of proteolysis)","NA","NA","NA","transmembrane 4 L six family member 20 [Source:HGNC Symbol;Acc:HGNC:26230]",0,0,1,0,1,1,"no","no"]
["MSTRG.9545","TMEM74B","ENST00000381894","GO:0016020(membrane);GO:0016021(integral component of membrane)","NA","NA","NA","transmembrane protein 74B [Source:HGNC Symbol;Acc:HGNC:15893]",{"v":0.0583385746606335,"d":"0.06"},0,"inf","inf",1,1,"up","no"]
["ENSG00000173867","AC013489.1","ENST00000561140","NA","NA","NA","NA",null,{"v":0.052546,"d":"0.05"},{"v":0.06324,"d":"0.06"},{"v":0.8308981657179,"d":"0.83"},{"v":-0.267256422724906,"d":"-0.27"},1,1,"down","no"]
["ENSG00000267606","AC006116.9","ENST00000591036","NA","NA","NA","NA",null,{"v":0.031250275,"d":"0.03"},0,"inf","inf",1,1,"up","no"]
["ENSG00000159173","TNNI1","ENST00000367312;ENST00000622580","GO:0046872(metal ion binding);GO:0003779(actin binding);GO:0005515(protein binding);GO:0005861(troponin complex);GO:0005829(cytosol);GO:0030049(muscle filament sliding);GO:0003009(skeletal muscle contraction);GO:0006942(regulation of striated muscle contraction);GO:0014883(transition between fast and slow fiber);GO:0055010(ventricular cardiac muscle tissue morphogenesis);GO:0060048(cardiac muscle contraction);GO:0060048(cardiac muscle contraction)","NA","NA","NA","troponin I1, slow skeletal type [Source:HGNC Symbol;Acc:HGNC:11945]",0,0,1,0,1,1,"no","no"]
["ENSG00000279071","AC073592.3","ENST00000625118","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000137975","CLCA2","ENST00000370565","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0046872(metal ion binding);GO:0005634(nucleus);GO:0016787(hydrolase activity);GO:0007155(cell adhesion);GO:0006811(ion transport);GO:0005886(plasma membrane);GO:0030054(cell junction);GO:0008233(peptidase activity);GO:0006508(proteolysis);GO:0005576(extracellular region);GO:0008237(metallopeptidase activity);GO:1902476(chloride transmembrane transport);GO:0006821(chloride transport);GO:0034220(ion transmembrane transport);GO:0004222(metalloendopeptidase activity);GO:0005229(intracellular calcium activated chloride channel activity);GO:0005254(chloride channel activity);GO:0005887(integral component of plasma membrane);GO:0009925(basal plasma membrane);GO:0015276(ligand-gated ion channel activity)","04924(Renin secretion);04972(Pancreatic secretion)","K05028","NA","chloride channel accessory 2 [Source:HGNC Symbol;Acc:HGNC:2016]",0,0,1,0,1,1,"no","no"]
["ENSG00000164045","CDC25A","ENST00000302506","GO:0016787(hydrolase activity);GO:0005622(intracellular);GO:0051301(cell division);GO:0004725(protein tyrosine phosphatase activity);GO:0006470(protein dephosphorylation);GO:0035335(peptidyl-tyrosine dephosphorylation);GO:0004721(phosphoprotein phosphatase activity);GO:0005515(protein binding);GO:0007049(cell cycle);GO:1902751(positive regulation of cell cycle G2/M phase transition);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0019901(protein kinase binding);GO:0016579(protein deubiquitination);GO:0008283(cell proliferation);GO:0000086(G2/M transition of mitotic cell cycle);GO:0000082(G1/S transition of mitotic cell cycle);GO:0006260(DNA replication);GO:0051087(chaperone binding);GO:0009314(response to radiation);GO:0000079(regulation of cyclin-dependent protein serine/threonine kinase activity);GO:0051726(regulation of cell cycle);GO:0034644(cellular response to UV)","04110(Cell cycle);04218(Cellular senescence);04914(Progesterone-mediated oocyte maturation);05206(MicroRNAs in cancer)","K06645","EC:3.1.3.48","cell division cycle 25A [Source:HGNC Symbol;Acc:HGNC:1725]",{"v":0.0516103378673792,"d":"0.05"},{"v":0.0741686691765849,"d":"0.07"},{"v":0.695850935986224,"d":"0.70"},{"v":-0.523149807414003,"d":"-0.52"},1,1,"down","no"]
["ENSG00000237770","SPATA31D2P","ENST00000429999","NA","NA","NA","NA","SPATA31 subfamily D member 2, pseudogene [Source:HGNC Symbol;Acc:HGNC:38607]",0,0,1,0,1,1,"no","no"]
["ENSG00000232727","YWHAEP1","ENST00000453697","NA","NA","NA","NA","tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon pseudogene 1 [Source:HGNC Symbol;Acc:HGNC:49442]",{"v":0.06962,"d":"0.07"},0,"inf","inf",1,1,"up","no"]
["ENSG00000141756","FKBP10","ENST00000321562;ENST00000489591;ENST00000487489","GO:0016853(isomerase activity);GO:0003755(peptidyl-prolyl cis-trans isomerase activity);GO:0000413(protein peptidyl-prolyl isomerization);GO:0046872(metal ion binding);GO:0005509(calcium ion binding);GO:0005783(endoplasmic reticulum);GO:0005528(FK506 binding);GO:0000412(histone peptidyl-prolyl isomerization);GO:0018208(peptidyl-proline modification);GO:0005730(nucleolus);GO:0061077(chaperone-mediated protein folding);GO:0005737(cytoplasm);GO:0005788(endoplasmic reticulum lumen);GO:0005788(endoplasmic reticulum lumen)","NA","NA","NA","FK506 binding protein 10 [Source:HGNC Symbol;Acc:HGNC:18169]",{"v":0.0496021436929558,"d":"0.05"},{"v":0.0476406421717763,"d":"0.05"},{"v":1.04117286064506,"d":"1.04"},{"v":0.058209611857466,"d":"0.06"},1,1,"up","no"]
["MSTRG.12182","VCAN-AS1","ENST00000512090","NA","NA","NA","NA","VCAN antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:40163]",{"v":0.169774,"d":"0.17"},{"v":0.045636,"d":"0.05"},{"v":3.72017705320361,"d":"3.72"},{"v":1.89537128469361,"d":"1.90"},1,1,"up","no"]
["ENSG00000226141","AC244107.1","ENST00000442033","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000214870","AC004540.1","ENST00000449537;ENST00000439120;ENST00000421862","NA","NA","NA","NA",null,{"v":0.0178692091656874,"d":"0.02"},{"v":0.0489758683901293,"d":"0.05"},{"v":0.364857423728474,"d":"0.36"},{"v":-1.45459528641374,"d":"-1.45"},1,1,"down","no"]
["ENSG00000164061","BSN","ENST00000296452","GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0005856(cytoskeleton);GO:0030054(cell junction);GO:0045202(synapse);GO:0007416(synapse assembly);GO:0048786(presynaptic active zone);GO:0005634(nucleus);GO:0043005(neuron projection);GO:0007268(chemical synaptic transmission);GO:0030425(dendrite);GO:0060076(excitatory synapse);GO:0035418(protein localization to synapse);GO:0099526(presynapse to nucleus signaling pathway);GO:0009986(cell surface);GO:0014069(postsynaptic density);GO:0030424(axon);GO:0044306(neuron projection terminus);GO:0048788(cytoskeleton of presynaptic active zone);GO:0098793(presynapse);GO:0098831(presynaptic active zone cytoplasmic component)","NA","NA","NA","bassoon presynaptic cytomatrix protein [Source:HGNC Symbol;Acc:HGNC:1117]",{"v":0.0515437460708783,"d":"0.05"},{"v":0.0199277704160246,"d":"0.02"},{"v":2.58652849740933,"d":"2.59"},{"v":1.37101708670681,"d":"1.37"},1,1,"up","no"]
["MSTRG.9388","AC007879.3;AC007879.4","ENST00000417096;ENST00000448786;ENST00000440545","NA","NA","NA","NA",null,{"v":0.146537607751938,"d":"0.15"},{"v":0.0557803186046512,"d":"0.06"},{"v":2.62704859738322,"d":"2.63"},{"v":1.39344288892045,"d":"1.39"},1,1,"up","no"]
["ENSG00000178074","C2orf69","ENST00000319974","GO:0005576(extracellular region)","NA","NA","NA","chromosome 2 open reading frame 69 [Source:HGNC Symbol;Acc:HGNC:26799]",{"v":1.94854298696462,"d":"1.95"},{"v":0.137664383612663,"d":"0.14"},{"v":14.1543000144983,"d":"14.15"},{"v":3.82316849898214,"d":"3.82"},1,1,"up","no"]
["ENSG00000280132","AC026471.6","ENST00000622954","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000212722","KRTAP4-9","ENST00000391415","GO:0005882(intermediate filament);GO:0045095(keratin filament);GO:0005829(cytosol);GO:0031424(keratinization);GO:0007568(aging);GO:0042633(hair cycle)","NA","NA","NA","keratin associated protein 4-9 [Source:HGNC Symbol;Acc:HGNC:18910]",0,0,1,0,1,1,"no","no"]
["ENSG00000214203","RPS4XP1","ENST00000482189","NA","NA","NA","NA","ribosomal protein S4X pseudogene 1 [Source:HGNC Symbol;Acc:HGNC:32444]",{"v":0.033748,"d":"0.03"},{"v":0.064666,"d":"0.06"},{"v":0.521881668883184,"d":"0.52"},{"v":-0.93820536676641,"d":"-0.94"},1,1,"down","no"]
["ENSG00000226915","AC068137.1","ENST00000429272","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000105366","SIGLEC8","ENST00000430817;ENST00000321424","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0030246(carbohydrate binding);GO:0007155(cell adhesion);GO:0005515(protein binding);GO:0007165(signal transduction);GO:0004888(transmembrane signaling receptor activity);GO:0004888(transmembrane signaling receptor activity)","NA","NA","NA","sialic acid binding Ig like lectin 8 [Source:HGNC Symbol;Acc:HGNC:10877]",{"v":0.548092448438978,"d":"0.55"},{"v":0.224103503311258,"d":"0.22"},{"v":2.44571120192499,"d":"2.45"},{"v":1.29025405548048,"d":"1.29"},1,1,"up","no"]
["ENSG00000107130","NCS1","ENST00000372398","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0043231(intracellular membrane-bounded organelle);GO:0046872(metal ion binding);GO:0005509(calcium ion binding);GO:0005794(Golgi apparatus);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0048471(perinuclear region of cytoplasm);GO:0030054(cell junction);GO:0045202(synapse);GO:0045211(postsynaptic membrane);GO:0070588(calcium ion transmembrane transport);GO:0000287(magnesium ion binding);GO:0005245(voltage-gated calcium channel activity);GO:0019901(protein kinase binding);GO:0010975(regulation of neuron projection development);GO:0045921(positive regulation of exocytosis);GO:0048015(phosphatidylinositol-mediated signaling);GO:0005829(cytosol);GO:0030424(axon);GO:0030425(dendrite);GO:0031045(dense core granule);GO:0031410(cytoplasmic vesicle);GO:0070062(extracellular exosome);GO:0014069(postsynaptic density)","NA","NA","NA","neuronal calcium sensor 1 [Source:HGNC Symbol;Acc:HGNC:3953]",{"v":0.080330659292872,"d":"0.08"},{"v":0.0768183692569484,"d":"0.08"},{"v":1.04572200724771,"d":"1.05"},{"v":0.0644993792437871,"d":"0.06"},1,1,"up","no"]
["ENSG00000151033","LYZL2","ENST00000375318","GO:0016787(hydrolase activity);GO:0008152(metabolic process);GO:0005576(extracellular region);GO:0016798(hydrolase activity, acting on glycosyl bonds);GO:0005615(extracellular space);GO:0003796(lysozyme activity);GO:0050829(defense response to Gram-negative bacterium);GO:0016998(cell wall macromolecule catabolic process);GO:0050830(defense response to Gram-positive bacterium)","NA","NA","NA","lysozyme like 2 [Source:HGNC Symbol;Acc:HGNC:29613]",0,0,1,0,1,1,"no","no"]
["ENSG00000260613","Z98885.2","ENST00000565177","NA","NA","NA","NA",null,{"v":0.033899,"d":"0.03"},0,"inf","inf",1,1,"up","no"]
["ENSG00000253966","AC008514.2","ENST00000522096","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000124882","EREG","ENST00000503689;ENST00000244869","GO:0005622(intracellular);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0018108(peptidyl-tyrosine phosphorylation);GO:0008083(growth factor activity);GO:0005886(plasma membrane);GO:0043547(positive regulation of GTPase activity);GO:0005576(extracellular region);GO:0007275(multicellular organism development);GO:0005615(extracellular space);GO:0030154(cell differentiation);GO:0046854(phosphatidylinositol phosphorylation);GO:0005887(integral component of plasma membrane);GO:0005515(protein binding);GO:0008285(negative regulation of cell proliferation);GO:0000165(MAPK cascade);GO:0001819(positive regulation of cytokine production);GO:0008284(positive regulation of cell proliferation);GO:0001550(ovarian cumulus expansion);GO:0045892(negative regulation of transcription, DNA-templated);GO:0046934(phosphatidylinositol-4,5-bisphosphate 3-kinase activity);GO:0014066(regulation of phosphatidylinositol 3-kinase signaling);GO:0038111(interleukin-7-mediated signaling pathway);GO:0048015(phosphatidylinositol-mediated signaling);GO:0009653(anatomical structure morphogenesis);GO:0007173(epidermal growth factor receptor signaling pathway);GO:0005088(Ras guanyl-nucleotide exchange factor activity);GO:0001525(angiogenesis);GO:0004713(protein tyrosine kinase activity);GO:0038128(ERBB2 signaling pathway);GO:1901185(negative regulation of ERBB signaling pathway);GO:2000145(regulation of cell motility);GO:0007267(cell-cell signaling);GO:0051781(positive regulation of cell division);GO:0045089(positive regulation of innate immune response);GO:0005154(epidermal growth factor receptor binding);GO:0001556(oocyte maturation);GO:0007143(female meiotic nuclear division);GO:0009299(mRNA transcription);GO:0009887(animal organ morphogenesis);GO:0019221(cytokine-mediated signaling pathway);GO:0030216(keratinocyte differentiation);GO:0030728(ovulation);GO:0042060(wound healing);GO:0042108(positive regulation of cytokine biosynthetic process);GO:0042327(positive regulation of phosphorylation);GO:0042700(luteinizing hormone signaling pathway);GO:0043434(response to peptide hormone);GO:0043616(keratinocyte proliferation);GO:0045410(positive regulation of interleukin-6 biosynthetic process);GO:0045740(positive regulation of DNA replication);GO:0045741(positive regulation of epidermal growth factor-activated receptor activity);GO:0045840(positive regulation of mitotic nuclear division);GO:0045860(positive regulation of protein kinase activity);GO:0048146(positive regulation of fibroblast proliferation);GO:0048160(primary follicle stage);GO:0048661(positive regulation of smooth muscle cell proliferation);GO:0050680(negative regulation of epithelial cell proliferation);GO:0051151(negative regulation of smooth muscle cell differentiation);GO:0051151(negative regulation of smooth muscle cell differentiation)","04012(ErbB signaling pathway);04012(ErbB signaling pathway)","K09784","NA","epiregulin [Source:HGNC Symbol;Acc:HGNC:3443]",{"v":0.0650408847297534,"d":"0.07"},{"v":0.106821949449012,"d":"0.11"},{"v":0.608871913171727,"d":"0.61"},{"v":-0.715789330906025,"d":"-0.72"},1,1,"down","no"]
["MSTRG.6352","AC004771.5","ENST00000575985","NA","NA","NA","NA",null,{"v":0.038372,"d":"0.04"},0,"inf","inf",1,1,"up","no"]
["ENSG00000229921","KIF25-AS1","ENST00000456585","NA","NA","NA","NA","KIF25 antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:20953]",{"v":0.0172017406088083,"d":"0.02"},0,"inf","inf",1,1,"up","no"]
["ENSG00000250195","AC109927.1","ENST00000511951","NA","NA","NA","NA",null,{"v":0.0368209608433735,"d":"0.04"},0,"inf","inf",1,1,"up","no"]
["ENSG00000213598","AL049873.1","ENST00000480540","NA","NA","NA","NA",null,0,{"v":0.046163,"d":"0.05"},"-inf","-inf",1,1,"down","no"]
["MSTRG.6220","AC010531.3","ENST00000569147","NA","NA","NA","NA",null,{"v":0.012343,"d":"0.01"},0,"inf","inf",1,1,"up","no"]
["ENSG00000223797","ENTPD3-AS1","ENST00000425156;ENST00000439293;ENST00000420850;ENST00000452768","NA","NA","NA","NA","ENTPD3 antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:26710]",{"v":0.218992142519419,"d":"0.22"},{"v":0.49661305504897,"d":"0.50"},{"v":0.440971376593845,"d":"0.44"},{"v":-1.18124308125039,"d":"-1.18"},1,1,"down","no"]
["ENSG00000236417","CTSLP1","ENST00000457530","NA","NA","NA","NA","cathepsin L pseudogene 1 [Source:HGNC Symbol;Acc:HGNC:2539]",0,0,1,0,1,1,"no","no"]
["ENSG00000147573","TRIM55","ENST00000315962;ENST00000517647","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0005622(intracellular);GO:0004871(signal transducer activity);GO:0007165(signal transduction);GO:0005874(microtubule);GO:0042802(identical protein binding);GO:0005515(protein binding);GO:0005515(protein binding)","NA","NA","NA","tripartite motif containing 55 [Source:HGNC Symbol;Acc:HGNC:14215]",{"v":0.0172410418695229,"d":"0.02"},0,"inf","inf",1,1,"up","no"]
["ENSG00000230204","FTH1P5","ENST00000425761","NA","NA","NA","NA","ferritin heavy chain 1 pseudogene 5 [Source:HGNC Symbol;Acc:HGNC:3996]",{"v":0.155561,"d":"0.16"},{"v":0.391761,"d":"0.39"},{"v":0.39708138380288,"d":"0.40"},{"v":-1.33249336969567,"d":"-1.33"},1,1,"down","no"]
["ENSG00000247877","AC021086.1","ENST00000499025;ENST00000504833","NA","NA","NA","NA",null,{"v":0.0310097933450088,"d":"0.03"},0,"inf","inf",1,1,"up","no"]
["ENSG00000182329","KIAA2012","ENST00000469462;ENST00000498697","NA","NA","NA","NA","KIAA2012 [Source:HGNC Symbol;Acc:HGNC:51250]",0,0,1,0,1,1,"no","no"]
["ENSG00000233421","LINC01783","ENST00000614408;ENST00000415386","NA","NA","NA","NA","long intergenic non-protein coding RNA 1783 [Source:HGNC Symbol;Acc:HGNC:52573]",0,0,1,0,1,1,"no","no"]
["ENSG00000151962","RBM46","ENST00000514866","GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0001829(trophectodermal cell differentiation);GO:0048255(mRNA stabilization);GO:0005634(nucleus)","NA","NA","NA","RNA binding motif protein 46 [Source:HGNC Symbol;Acc:HGNC:28401]",0,0,1,0,1,1,"no","no"]
["MSTRG.464","AL031289.1","ENST00000440100","NA","NA","NA","NA",null,{"v":0.046568,"d":"0.05"},{"v":0.050075,"d":"0.05"},{"v":0.929965052421368,"d":"0.93"},{"v":-0.104751593339516,"d":"-0.10"},1,1,"down","no"]
["ENSG00000261097","LINC00563","ENST00000566370","NA","NA","NA","NA","long intergenic non-protein coding RNA 563 [Source:HGNC Symbol;Acc:HGNC:43707]",{"v":0.260574,"d":"0.26"},{"v":0.289727,"d":"0.29"},{"v":0.899377690032341,"d":"0.90"},{"v":-0.153000997937261,"d":"-0.15"},1,1,"down","no"]
["MSTRG.4544","AL049780.3","ENST00000624612","NA","NA","NA","NA",null,{"v":0.135448,"d":"0.14"},0,"inf","inf",1,1,"up","no"]
["ENSG00000224533","TMLHE-AS1","ENST00000433624","NA","NA","NA","NA","TMLHE antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:44261]",{"v":0.301910815176152,"d":"0.30"},{"v":0.236090923577236,"d":"0.24"},{"v":1.27879043633536,"d":"1.28"},{"v":0.354779859816666,"d":"0.35"},1,1,"up","no"]
["MSTRG.6741","AC244093.3","ENST00000615419","NA","NA","NA","NA",null,0,{"v":0.028701,"d":"0.03"},"-inf","-inf",1,1,"down","no"]
["MSTRG.5994","TK2","ENST00000565729","GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0006139(nucleobase-containing compound metabolic process);GO:0005739(mitochondrion);GO:0019206(nucleoside kinase activity);GO:0009165(nucleotide biosynthetic process);GO:0005759(mitochondrial matrix);GO:0009157(deoxyribonucleoside monophosphate biosynthetic process);GO:0004797(thymidine kinase activity);GO:0071897(DNA biosynthetic process);GO:0043097(pyrimidine nucleoside salvage);GO:0004137(deoxycytidine kinase activity);GO:0046092(deoxycytidine metabolic process);GO:0046104(thymidine metabolic process)","00240(Pyrimidine metabolism);00983(Drug metabolism - other enzymes)","NA","NA","thymidine kinase 2, mitochondrial [Source:HGNC Symbol;Acc:HGNC:11831]",{"v":0.022769,"d":"0.02"},0,"inf","inf",1,1,"up","no"]
["ENSG00000159307","SCUBE1","ENST00000360835","GO:0016020(membrane);GO:0005509(calcium ion binding);GO:0005886(plasma membrane);GO:0005576(extracellular region);GO:0006954(inflammatory response);GO:0007165(signal transduction);GO:0030154(cell differentiation);GO:0009986(cell surface);GO:0007596(blood coagulation);GO:0046982(protein heterodimerization activity);GO:0022617(extracellular matrix disassembly);GO:0045446(endothelial cell differentiation);GO:0042802(identical protein binding);GO:0005615(extracellular space);GO:0051260(protein homooligomerization);GO:0009897(external side of plasma membrane);GO:0009791(post-embryonic development);GO:0007512(adult heart development);GO:0045880(positive regulation of smoothened signaling pathway);GO:0019897(extrinsic component of plasma membrane)","NA","NA","NA","signal peptide, CUB domain and EGF like domain containing 1 [Source:HGNC Symbol;Acc:HGNC:13441]",{"v":0.00834508446641945,"d":"0.01"},{"v":0.002267923197363,"d":"0.00"},{"v":3.67961511047755,"d":"3.68"},{"v":1.87955486757427,"d":"1.88"},1,1,"up","no"]
["ENSG00000140067","FAM181A","ENST00000267594","NA","NA","NA","NA","family with sequence similarity 181 member A [Source:HGNC Symbol;Acc:HGNC:20491]",0,0,1,0,1,1,"no","no"]
["ENSG00000229487","ALG13-AS1","ENST00000430794","NA","NA","NA","NA","ALG13 antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:41277]",{"v":0.299893,"d":"0.30"},0,"inf","inf",1,1,"up","no"]
["ENSG00000257302","FAHD2P1","ENST00000546381","NA","NA","NA","NA","fumarylacetoacetate hydrolase domain containing 2 pseudogene 1 [Source:HGNC Symbol;Acc:HGNC:32441]",0,0,1,0,1,1,"no","no"]
["ENSG00000204065","TCEAL5","ENST00000372680","GO:0005634(nucleus);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0005515(protein binding);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0050699(WW domain binding)","NA","NA","NA","transcription elongation factor A like 5 [Source:HGNC Symbol;Acc:HGNC:22282]",0,0,1,0,1,1,"no","no"]
["ENSG00000258057","BCDIN3D-AS1","ENST00000548872","NA","NA","NA","NA","BCDIN3D antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:44113]",{"v":0.108235561070831,"d":"0.11"},{"v":0.0496711606246514,"d":"0.05"},{"v":2.17904231972213,"d":"2.18"},{"v":1.12369421566464,"d":"1.12"},1,1,"up","no"]
["ENSG00000158246","FAM46B","ENST00000289166","GO:0005515(protein binding)","NA","NA","NA","family with sequence similarity 46 member B [Source:HGNC Symbol;Acc:HGNC:28273]",{"v":0.044865,"d":"0.04"},0,"inf","inf",1,1,"up","no"]
["ENSG00000259940","AC109449.1","ENST00000567108","NA","NA","NA","NA",null,0,{"v":0.119241,"d":"0.12"},"-inf","-inf",1,1,"down","no"]
["ENSG00000111432","FZD10","ENST00000229030;ENST00000539839","GO:0005737(cytoplasm);GO:0043507(positive regulation of JUN kinase activity);GO:0034260(negative regulation of GTPase activity);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005654(nucleoplasm);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0004871(signal transducer activity);GO:0007165(signal transduction);GO:0004888(transmembrane signaling receptor activity);GO:0004930(G-protein coupled receptor activity);GO:0007166(cell surface receptor signaling pathway);GO:0007186(G-protein coupled receptor signaling pathway);GO:0007275(multicellular organism development);GO:0016055(Wnt signaling pathway);GO:0042813(Wnt-activated receptor activity);GO:0005887(integral component of plasma membrane);GO:0060070(canonical Wnt signaling pathway);GO:0009986(cell surface);GO:0043547(positive regulation of GTPase activity);GO:0030182(neuron differentiation);GO:0071300(cellular response to retinoic acid);GO:0017147(Wnt-protein binding);GO:0038031(non-canonical Wnt signaling pathway via JNK cascade);GO:0032956(regulation of actin cytoskeleton organization);GO:0032956(regulation of actin cytoskeleton organization)","04310(Wnt signaling pathway);04390(Hippo signaling pathway);04150(mTOR signaling pathway);04550(Signaling pathways regulating pluripotency of stem cells);04916(Melanogenesis);05200(Pathways in cancer);05205(Proteoglycans in cancer);05225(Hepatocellular carcinoma);05226(Gastric cancer);05217(Basal cell carcinoma);05224(Breast cancer);05166(HTLV-I infection);05165(Human papillomavirus infection);05165(Human papillomavirus infection)","K02842","NA","frizzled class receptor 10 [Source:HGNC Symbol;Acc:HGNC:4039]",0,0,1,0,1,1,"no","no"]
["ENSG00000223704","LINC01422","ENST00000434868","NA","NA","NA","NA","long intergenic non-protein coding RNA 1422 [Source:HGNC Symbol;Acc:HGNC:50728]",{"v":0.161753,"d":"0.16"},{"v":0.075711,"d":"0.08"},{"v":2.13645309136057,"d":"2.14"},{"v":1.0952176410984,"d":"1.10"},1,1,"up","no"]
["MSTRG.10574","PRR34","ENST00000396008","NA","NA","NA","NA","proline rich 34 [Source:HGNC Symbol;Acc:HGNC:25606]",{"v":0.30171,"d":"0.30"},{"v":0.09021,"d":"0.09"},{"v":3.3445294313269,"d":"3.34"},{"v":1.74180324080758,"d":"1.74"},1,1,"up","no"]
["MSTRG.5985","AC009118.3","ENST00000622896","NA","NA","NA","NA",null,0,{"v":0.174114,"d":"0.17"},"-inf","-inf",1,1,"down","no"]
["ENSG00000258806","OR11H7","ENST00000553765","NA","NA","NA","NA","olfactory receptor family 11 subfamily H member 7 (gene/pseudogene) [Source:HGNC Symbol;Acc:HGNC:15350]",0,0,1,0,1,1,"no","no"]
["ENSG00000243543","WFDC6","ENST00000372670","GO:0005576(extracellular region);GO:0004867(serine-type endopeptidase inhibitor activity);GO:0010951(negative regulation of endopeptidase activity);GO:0030414(peptidase inhibitor activity);GO:0010466(negative regulation of peptidase activity)","NA","NA","NA","WAP four-disulfide core domain 6 [Source:HGNC Symbol;Acc:HGNC:16164]",0,0,1,0,1,1,"no","no"]
["ENSG00000277925","Telomerase-vert","ENST00000363312","NA","05200(Pathways in cancer);05225(Hepatocellular carcinoma);05226(Gastric cancer)","K22183","NA","Vertebrate telomerase RNA [Source:RFAM;Acc:RF00024]",0,0,1,0,1,1,"no","no"]
["ENSG00000216966","AL353747.1","ENST00000404577","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000198691","ABCA4","ENST00000370225","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005215(transporter activity);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0005887(integral component of plasma membrane);GO:0007601(visual perception);GO:0042626(ATPase activity, coupled to transmembrane movement of substances);GO:0016887(ATPase activity);GO:0050896(response to stimulus);GO:0055085(transmembrane transport);GO:0001523(retinoid metabolic process);GO:0043231(intracellular membrane-bounded organelle);GO:0097381(photoreceptor disc membrane);GO:0045332(phospholipid translocation);GO:0007603(phototransduction, visible light);GO:0090555(phosphatidylethanolamine-translocating ATPase activity);GO:0004012(phospholipid-translocating ATPase activity);GO:0005395(eye pigment precursor transporter activity);GO:0005548(phospholipid transporter activity);GO:0006649(phospholipid transfer to membrane);GO:0045494(photoreceptor cell maintenance);GO:0001750(photoreceptor outer segment)","02010(ABC transporters)","K05644","NA","ATP binding cassette subfamily A member 4 [Source:HGNC Symbol;Acc:HGNC:34]",0,0,1,0,1,1,"no","no"]
["ENSG00000232883","AL451081.2","ENST00000448115","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000170099","SERPINA6","ENST00000555056;ENST00000557225","GO:0005615(extracellular space);GO:0006810(transport);GO:0010951(negative regulation of endopeptidase activity);GO:0005576(extracellular region);GO:0008289(lipid binding);GO:0070062(extracellular exosome);GO:0005496(steroid binding);GO:0004867(serine-type endopeptidase inhibitor activity);GO:0008211(glucocorticoid metabolic process);GO:0008211(glucocorticoid metabolic process)","NA","NA","NA","serpin family A member 6 [Source:HGNC Symbol;Acc:HGNC:1540]",0,0,1,0,1,1,"no","no"]
["ENSG00000135577","NMBR","ENST00000258042","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0004930(G-protein coupled receptor activity);GO:0007186(G-protein coupled receptor signaling pathway);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0004871(signal transducer activity);GO:0007165(signal transduction);GO:0005887(integral component of plasma membrane);GO:0007200(phospholipase C-activating G-protein coupled receptor signaling pathway);GO:0004946(bombesin receptor activity);GO:0008528(G-protein coupled peptide receptor activity);GO:0031989(bombesin receptor signaling pathway)","04080(Neuroactive ligand-receptor interaction)","K04168","NA","neuromedin B receptor [Source:HGNC Symbol;Acc:HGNC:7843]",0,0,1,0,1,1,"no","no"]
["ENSG00000163817","SLC6A20","ENST00000358525","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005887(integral component of plasma membrane);GO:0015293(symporter activity);GO:0055085(transmembrane transport);GO:0005886(plasma membrane);GO:0003333(amino acid transmembrane transport);GO:0005515(protein binding);GO:0005328(neurotransmitter:sodium symporter activity);GO:0006836(neurotransmitter transport);GO:0006865(amino acid transport);GO:0016324(apical plasma membrane);GO:0015171(amino acid transmembrane transporter activity);GO:0015824(proline transport);GO:0015816(glycine transport)","NA","NA","NA","solute carrier family 6 member 20 [Source:HGNC Symbol;Acc:HGNC:30927]",{"v":0.0159730221019396,"d":"0.02"},0,"inf","inf",1,1,"up","no"]
["MSTRG.3679","AC007622.2","ENST00000546714","NA","NA","NA","NA",null,{"v":0.096698016336056,"d":"0.10"},{"v":0.0586461143523921,"d":"0.06"},{"v":1.64883926929955,"d":"1.65"},{"v":0.721450770099628,"d":"0.72"},1,1,"up","no"]
["ENSG00000203963","C1orf141","ENST00000371004;ENST00000475209","NA","NA","NA","NA","chromosome 1 open reading frame 141 [Source:HGNC Symbol;Acc:HGNC:32044]",0,0,1,0,1,1,"no","no"]
["ENSG00000196263","ZNF471","ENST00000593197;ENST00000308031","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0005622(intracellular);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding)","NA","NA","NA","zinc finger protein 471 [Source:HGNC Symbol;Acc:HGNC:23226]",{"v":0.0341432849771488,"d":"0.03"},{"v":0.00750306132979508,"d":"0.01"},{"v":4.55058055324217,"d":"4.55"},{"v":2.18605061297156,"d":"2.19"},1,1,"up","no"]
["ENSG00000132631","SCP2D1","ENST00000377428","GO:0015248(sterol transporter activity);GO:0006694(steroid biosynthetic process);GO:0015914(phospholipid transport);GO:0032934(sterol binding);GO:0030301(cholesterol transport)","NA","NA","NA","SCP2 sterol binding domain containing 1 [Source:HGNC Symbol;Acc:HGNC:16211]",0,0,1,0,1,1,"no","no"]
["ENSG00000235631","RNF148","ENST00000434824","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0046872(metal ion binding)","NA","NA","NA","ring finger protein 148 [Source:HGNC Symbol;Acc:HGNC:22411]",0,0,1,0,1,1,"no","no"]
["ENSG00000120149","MSX2","ENST00000239243","GO:0005634(nucleus);GO:0016607(nuclear speck);GO:0005829(cytosol);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0043565(sequence-specific DNA binding);GO:0007275(multicellular organism development);GO:0005515(protein binding);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0001503(ossification);GO:0044212(transcription regulatory region DNA binding);GO:0045892(negative regulation of transcription, DNA-templated);GO:0001649(osteoblast differentiation);GO:0003712(transcription cofactor activity);GO:2000678(negative regulation of transcription regulatory region DNA binding);GO:0000977(RNA polymerase II regulatory region sequence-specific DNA binding);GO:0000989(transcription factor activity, transcription factor binding);GO:0001227(transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding);GO:0008134(transcription factor binding);GO:0002063(chondrocyte development);GO:0002076(osteoblast development);GO:0003148(outflow tract septum morphogenesis);GO:0003151(outflow tract morphogenesis);GO:0003198(epithelial to mesenchymal transition involved in endocardial cushion formation);GO:0003416(endochondral bone growth);GO:0008285(negative regulation of cell proliferation);GO:0009952(anterior/posterior pattern specification);GO:0023019(signal transduction involved in regulation of gene expression);GO:0030326(embryonic limb morphogenesis);GO:0030509(BMP signaling pathway);GO:0030513(positive regulation of BMP signaling pathway);GO:0032792(negative regulation of CREB transcription factor activity);GO:0035115(embryonic forelimb morphogenesis);GO:0035116(embryonic hindlimb morphogenesis);GO:0035313(wound healing, spreading of epidermal cells);GO:0035880(embryonic nail plate morphogenesis);GO:0042060(wound healing);GO:0042476(odontogenesis);GO:0042733(embryonic digit morphogenesis);GO:0042981(regulation of apoptotic process);GO:0043066(negative regulation of apoptotic process);GO:0045599(negative regulation of fat cell differentiation);GO:0045617(negative regulation of keratinocyte differentiation);GO:0045669(positive regulation of osteoblast differentiation);GO:0048863(stem cell differentiation);GO:0051216(cartilage development);GO:0051795(positive regulation of timing of catagen);GO:0060346(bone trabecula formation);GO:0060349(bone morphogenesis);GO:0060363(cranial suture morphogenesis);GO:0060364(frontal suture morphogenesis);GO:0060444(branching involved in mammary gland duct morphogenesis);GO:0061180(mammary gland epithelium development);GO:0061312(BMP signaling pathway involved in heart development);GO:0070166(enamel mineralization);GO:0071363(cellular response to growth factor stimulus);GO:0071392(cellular response to estradiol stimulus);GO:0090427(activation of meiosis);GO:2001055(positive regulation of mesenchymal cell apoptotic process)","05166(HTLV-I infection)","K09341","NA","msh homeobox 2 [Source:HGNC Symbol;Acc:HGNC:7392]",0,0,1,0,1,1,"no","no"]
["ENSG00000114993","RTKN","ENST00000305557;ENST00000640304;ENST00000472518;ENST00000272430;ENST00000492013;ENST00000484453","GO:0000166(nucleotide binding);GO:0007165(signal transduction);GO:0005525(GTP binding);GO:0005515(protein binding);GO:0006915(apoptotic process);GO:0007266(Rho protein signal transduction);GO:0017049(GTP-Rho binding);GO:0005575(cellular_component);GO:0005829(cytosol);GO:0042981(regulation of apoptotic process);GO:0034260(negative regulation of GTPase activity);GO:0005095(GTPase inhibitor activity);GO:0032185(septin cytoskeleton organization);GO:0017048(Rho GTPase binding);GO:0017048(Rho GTPase binding)","NA","NA","NA","rhotekin [Source:HGNC Symbol;Acc:HGNC:10466]",{"v":0.249036482851638,"d":"0.25"},{"v":0.0951394258188825,"d":"0.10"},{"v":2.61759497398828,"d":"2.62"},{"v":1.38824188329406,"d":"1.39"},1,1,"up","no"]
["ENSG00000213714","FAM209B","ENST00000371325","GO:0005634(nucleus);GO:0016020(membrane);GO:0016021(integral component of membrane)","NA","NA","NA","family with sequence similarity 209 member B [Source:HGNC Symbol;Acc:HGNC:16101]",{"v":0.172092,"d":"0.17"},{"v":0.109997,"d":"0.11"},{"v":1.56451539587443,"d":"1.56"},{"v":0.645715855729622,"d":"0.65"},1,1,"up","no"]
["MSTRG.5084","AC090971.2","ENST00000558142","NA","NA","NA","NA",null,{"v":0.08452,"d":"0.08"},0,"inf","inf",1,1,"up","no"]
["MSTRG.13083","AL035701.1","ENST00000437249;ENST00000444038","NA","NA","NA","NA",null,{"v":0.346008304465494,"d":"0.35"},{"v":0.206445951285521,"d":"0.21"},{"v":1.67602368712455,"d":"1.68"},{"v":0.745042538688598,"d":"0.75"},1,1,"up","no"]
["ENSG00000237603","HMGB3P12","ENST00000438745","NA","NA","NA","NA","high mobility group box 3 pseudogene 12 [Source:HGNC Symbol;Acc:HGNC:39304]",0,0,1,0,1,1,"no","no"]
["ENSG00000135119","RNFT2","ENST00000319176;ENST00000551251;ENST00000257575;ENST00000392549","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0046872(metal ion binding);GO:0046872(metal ion binding)","NA","NA","NA","ring finger protein, transmembrane 2 [Source:HGNC Symbol;Acc:HGNC:25905]",{"v":0.12555696993988,"d":"0.13"},{"v":0.0776624960690612,"d":"0.08"},{"v":1.61670016153265,"d":"1.62"},{"v":0.693052136708383,"d":"0.69"},1,1,"up","no"]
["MSTRG.13621","AC004951.1","ENST00000447643","NA","NA","NA","NA",null,{"v":0.603285,"d":"0.60"},{"v":0.124813,"d":"0.12"},{"v":4.8335109323548,"d":"4.83"},{"v":2.27307150472096,"d":"2.27"},1,1,"up","no"]
["ENSG00000179044","EXOC3L1","ENST00000314586;ENST00000563536;ENST00000545725;ENST00000564324","GO:0006887(exocytosis);GO:0000145(exocyst);GO:0031410(cytoplasmic vesicle);GO:0030072(peptide hormone secretion);GO:0030141(secretory granule);GO:0003674(molecular_function);GO:0000149(SNARE binding);GO:0030133(transport vesicle);GO:0051601(exocyst localization);GO:0051601(exocyst localization)","NA","NA","NA","exocyst complex component 3 like 1 [Source:HGNC Symbol;Acc:HGNC:27540]",{"v":0.131519805004875,"d":"0.13"},{"v":0.0991631738706532,"d":"0.10"},{"v":1.3262968486308,"d":"1.33"},{"v":0.407403712190823,"d":"0.41"},1,1,"up","no"]
["ENSG00000093100","AC016026.1","ENST00000476405","NA","NA","NA","NA",null,{"v":0.024547,"d":"0.02"},0,"inf","inf",1,1,"up","no"]
["ENSG00000230054","AL160275.1","ENST00000423632","NA","NA","NA","NA",null,0,{"v":0.0883541944444444,"d":"0.09"},"-inf","-inf",1,1,"down","no"]
["MSTRG.3576","PPP1R12A-AS1","ENST00000552885","NA","NA","NA","NA","PPP1R12A antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:51903]",{"v":0.065593,"d":"0.07"},0,"inf","inf",1,1,"up","no"]
["ENSG00000282840","AC004554.2","ENST00000634846","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000163827","LRRC2","ENST00000395905","NA","NA","NA","NA","leucine rich repeat containing 2 [Source:HGNC Symbol;Acc:HGNC:14676]",{"v":0.0283457310565635,"d":"0.03"},{"v":0.0268570971184632,"d":"0.03"},{"v":1.05542795379315,"d":"1.06"},{"v":0.0778280999992454,"d":"0.08"},1,1,"up","no"]
["ENSG00000197446","CYP2F1","ENST00000531409;ENST00000331105","GO:0055114(oxidation-reduction process);GO:0005506(iron ion binding);GO:0016705(oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen);GO:0020037(heme binding);GO:0016020(membrane);GO:0046872(metal ion binding);GO:0004497(monooxygenase activity);GO:0016491(oxidoreductase activity);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0008392(arachidonic acid epoxygenase activity);GO:0008395(steroid hydroxylase activity);GO:0019373(epoxygenase P450 pathway);GO:0070330(aromatase activity);GO:0019825(oxygen binding);GO:0043231(intracellular membrane-bounded organelle);GO:0006805(xenobiotic metabolic process);GO:0031090(organelle membrane);GO:0016712(oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen);GO:0018931(naphthalene metabolic process);GO:0009636(response to toxic substance);GO:0018979(trichloroethylene metabolic process);GO:0018979(trichloroethylene metabolic process)","00980(Metabolism of xenobiotics by cytochrome P450);00980(Metabolism of xenobiotics by cytochrome P450)","K07416","EC:1.14.14.1","cytochrome P450 family 2 subfamily F member 1 [Source:HGNC Symbol;Acc:HGNC:2632]",0,0,1,0,1,1,"no","no"]
["ENSG00000180919","OR56B4","ENST00000316529","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0007186(G-protein coupled receptor signaling pathway);GO:0005886(plasma membrane);GO:0004871(signal transducer activity);GO:0007165(signal transduction);GO:0004930(G-protein coupled receptor activity);GO:0004984(olfactory receptor activity);GO:0007608(sensory perception of smell);GO:0050896(response to stimulus);GO:0050911(detection of chemical stimulus involved in sensory perception of smell)","04740(Olfactory transduction)","K04257","NA","olfactory receptor family 56 subfamily B member 4 [Source:HGNC Symbol;Acc:HGNC:15248]",{"v":0.045653,"d":"0.05"},0,"inf","inf",1,1,"up","no"]
["ENSG00000215784","FAM72D","ENST00000400889","GO:0043231(intracellular membrane-bounded organelle);GO:0005829(cytosol)","NA","NA","NA","family with sequence similarity 72 member D [Source:HGNC Symbol;Acc:HGNC:33593]",{"v":0.044359,"d":"0.04"},{"v":0.083016,"d":"0.08"},{"v":0.534342777295943,"d":"0.53"},{"v":-0.90416257684263,"d":"-0.90"},1,1,"down","no"]
["ENSG00000268062","AL031274.2","ENST00000599419","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000234801","MORF4","ENST00000447135","NA","NA","NA","NA","mortality factor 4 (pseudogene) [Source:HGNC Symbol;Acc:HGNC:15773]",0,{"v":0.026206,"d":"0.03"},"-inf","-inf",1,1,"down","no"]
["ENSG00000277297","ATP5A1P10","ENST00000622403","NA","NA","NA","NA","ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1 pseudogene 10 [Source:HGNC Symbol;Acc:HGNC:37668]",0,0,1,0,1,1,"no","no"]
["ENSG00000255875","AC008813.1","ENST00000536597","NA","NA","NA","NA",null,{"v":0.089835,"d":"0.09"},0,"inf","inf",1,1,"up","no"]
["ENSG00000253305","PCDHGB6","ENST00000520790;ENST00000616430","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005509(calcium ion binding);GO:0007155(cell adhesion);GO:0007156(homophilic cell adhesion via plasma membrane adhesion molecules);GO:0005886(plasma membrane);GO:0005887(integral component of plasma membrane);GO:0007399(nervous system development);GO:0007267(cell-cell signaling);GO:0007267(cell-cell signaling)","NA","NA","NA","protocadherin gamma subfamily B, 6 [Source:HGNC Symbol;Acc:HGNC:8713]",{"v":0.0467874618106753,"d":"0.05"},{"v":0.0112562359186081,"d":"0.01"},{"v":4.15658148505303,"d":"4.16"},{"v":2.05539749421331,"d":"2.06"},1,1,"up","no"]
["ENSG00000110092","CCND1","ENST00000535993;ENST00000227507;ENST00000542367","GO:0001934(positive regulation of protein phosphorylation);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005654(nucleoplasm);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0051301(cell division);GO:0005515(protein binding);GO:0045859(regulation of protein kinase activity);GO:0006974(cellular response to DNA damage stimulus);GO:0007049(cell cycle);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0003714(transcription corepressor activity);GO:0005829(cytosol);GO:0019901(protein kinase binding);GO:0071157(negative regulation of cell cycle arrest);GO:0019899(enzyme binding);GO:0008134(transcription factor binding);GO:0070064(proline-rich region binding);GO:0010971(positive regulation of G2/M transition of mitotic cell cycle);GO:0005622(intracellular);GO:0042826(histone deacetylase binding);GO:0017053(transcriptional repressor complex);GO:0042493(response to drug);GO:0004693(cyclin-dependent protein serine/threonine kinase activity);GO:0070141(response to UV-A);GO:0000082(G1/S transition of mitotic cell cycle);GO:0045787(positive regulation of cell cycle);GO:0000307(cyclin-dependent protein kinase holoenzyme complex);GO:0031571(mitotic G1 DNA damage checkpoint);GO:0044321(response to leptin);GO:0004672(protein kinase activity);GO:0016301(kinase activity);GO:0016538(cyclin-dependent protein serine/threonine kinase regulator activity);GO:0032403(protein complex binding);GO:0000320(re-entry into mitotic cell cycle);GO:0001889(liver development);GO:0006468(protein phosphorylation);GO:0007595(lactation);GO:0008284(positive regulation of cell proliferation);GO:0010033(response to organic substance);GO:0010039(response to iron ion);GO:0010165(response to X-ray);GO:0010243(response to organonitrogen compound);GO:0014070(response to organic cyclic compound);GO:0016055(Wnt signaling pathway);GO:0030178(negative regulation of Wnt signaling pathway);GO:0030857(negative regulation of epithelial cell differentiation);GO:0030968(endoplasmic reticulum unfolded protein response);GO:0031100(animal organ regeneration);GO:0032026(response to magnesium ion);GO:0032355(response to estradiol);GO:0033197(response to vitamin E);GO:0033327(Leydig cell differentiation);GO:0033598(mammary gland epithelial cell proliferation);GO:0033601(positive regulation of mammary gland epithelial cell proliferation);GO:0043627(response to estrogen);GO:0045444(fat cell differentiation);GO:0045471(response to ethanol);GO:0045737(positive regulation of cyclin-dependent protein serine/threonine kinase activity);GO:0048545(response to steroid hormone);GO:0051384(response to glucocorticoid);GO:0051412(response to corticosterone);GO:0051592(response to calcium ion);GO:0051726(regulation of cell cycle);GO:0060070(canonical Wnt signaling pathway);GO:0060749(mammary gland alveolus development);GO:0071310(cellular response to organic substance);GO:0097421(liver regeneration);GO:2000045(regulation of G1/S transition of mitotic cell cycle);GO:0005923(bicellular tight junction);GO:0005923(bicellular tight junction)","04310(Wnt signaling pathway);04340(Hedgehog signaling pathway);04390(Hippo signaling pathway);04371(Apelin signaling pathway);04630(Jak-STAT signaling pathway);04068(FoxO signaling pathway);04151(PI3K-Akt signaling pathway);04152(AMPK signaling pathway);04110(Cell cycle);04115(p53 signaling pathway);04218(Cellular senescence);04510(Focal adhesion);04530(Tight junction);04917(Prolactin signaling pathway);04921(Oxytocin signaling pathway);04919(Thyroid hormone signaling pathway);05200(Pathways in cancer);05206(MicroRNAs in cancer);05205(Proteoglycans in cancer);05203(Viral carcinogenesis);05210(Colorectal cancer);05212(Pancreatic cancer);05225(Hepatocellular carcinoma);05226(Gastric cancer);05214(Glioma);05216(Thyroid cancer);05221(Acute myeloid leukemia);05220(Chronic myeloid leukemia);05218(Melanoma);05219(Bladder cancer);05215(Prostate cancer);05213(Endometrial cancer);05224(Breast cancer);05222(Small cell lung cancer);05223(Non-small cell lung cancer);05416(Viral myocarditis);04933(AGE-RAGE signaling pathway in diabetic complications);05166(HTLV-I infection);05162(Measles);05161(Hepatitis B);05167(Kaposi's sarcoma-associated herpesvirus infection);05165(Human papillomavirus infection);01522(Endocrine resistance);01522(Endocrine resistance)","K04503","NA","cyclin D1 [Source:HGNC Symbol;Acc:HGNC:1582]",{"v":0.225873000207039,"d":"0.23"},{"v":0.0779183561076605,"d":"0.08"},{"v":2.89884196087182,"d":"2.90"},{"v":1.53547668266406,"d":"1.54"},1,1,"up","no"]
["ENSG00000106304","SPAM1","ENST00000340011","GO:0016787(hydrolase activity);GO:0003824(catalytic activity);GO:0005975(carbohydrate metabolic process);GO:0008152(metabolic process);GO:0016798(hydrolase activity, acting on glycosyl bonds);GO:0004415(hyalurononglucosaminidase activity);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0007155(cell adhesion);GO:0005886(plasma membrane);GO:0031225(anchored component of membrane);GO:0035036(sperm-egg recognition);GO:0007339(binding of sperm to zona pellucida);GO:0007342(fusion of sperm to egg plasma membrane)","00531(Glycosaminoglycan degradation)","K01197","EC:3.2.1.35","sperm adhesion molecule 1 [Source:HGNC Symbol;Acc:HGNC:11217]",0,0,1,0,1,1,"no","no"]
["ENSG00000232938","RPL23AP87","ENST00000425566","NA","NA","NA","NA","ribosomal protein L23a pseudogene 87 [Source:HGNC Symbol;Acc:HGNC:51578]",{"v":0.023546,"d":"0.02"},0,"inf","inf",1,1,"up","no"]
["ENSG00000115665","SLC5A7","ENST00000264047","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005215(transporter activity);GO:0055085(transmembrane transport);GO:0015293(symporter activity);GO:0006811(ion transport);GO:0005886(plasma membrane);GO:0006814(sodium ion transport);GO:0030054(cell junction);GO:0045202(synapse);GO:0098793(presynapse);GO:0005887(integral component of plasma membrane);GO:0007269(neurotransmitter secretion);GO:0030425(dendrite);GO:0043204(perikaryon);GO:0031594(neuromuscular junction);GO:0030424(axon);GO:0007274(neuromuscular synaptic transmission);GO:0007271(synaptic transmission, cholinergic);GO:0042136(neurotransmitter biosynthetic process);GO:0015220(choline transmembrane transporter activity);GO:0008292(acetylcholine biosynthetic process);GO:0005307(choline:sodium symporter activity);GO:0033265(choline binding);GO:0015871(choline transport);GO:0043025(neuronal cell body)","04725(Cholinergic synapse);05231(Choline metabolism in cancer)","K14387","NA","solute carrier family 5 member 7 [Source:HGNC Symbol;Acc:HGNC:14025]",0,0,1,0,1,1,"no","no"]
["ENSG00000181961","OR4A16","ENST00000314721","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0004930(G-protein coupled receptor activity);GO:0007186(G-protein coupled receptor signaling pathway);GO:0005886(plasma membrane);GO:0004871(signal transducer activity);GO:0007165(signal transduction);GO:0004984(olfactory receptor activity);GO:0007608(sensory perception of smell);GO:0050896(response to stimulus);GO:0050911(detection of chemical stimulus involved in sensory perception of smell);GO:0004888(transmembrane signaling receptor activity);GO:0050907(detection of chemical stimulus involved in sensory perception)","04740(Olfactory transduction)","K04257","NA","olfactory receptor family 4 subfamily A member 16 [Source:HGNC Symbol;Acc:HGNC:15153]",0,0,1,0,1,1,"no","no"]
["ENSG00000269586","CT45A10","ENST00000611668","NA","NA","NA","NA","cancer/testis antigen family 45 member A10 [Source:HGNC Symbol;Acc:HGNC:51263]",0,0,1,0,1,1,"no","no"]
["ENSG00000257042","AC008011.2","ENST00000538113","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["MSTRG.2252","AC116535.1","ENST00000499765","NA","NA","NA","NA",null,{"v":0.135681,"d":"0.14"},{"v":0.010898,"d":"0.01"},{"v":12.4500825839604,"d":"12.45"},{"v":3.63808340690561,"d":"3.64"},1,1,"up","no"]
["MSTRG.2761","AP003086.1","ENST00000513207","NA","NA","NA","NA",null,{"v":0.161753,"d":"0.16"},{"v":0.092981,"d":"0.09"},{"v":1.7396349791893,"d":"1.74"},{"v":0.798784622764689,"d":"0.80"},1,1,"up","no"]
["ENSG00000177181","RIMKLA","ENST00000431473","GO:0005524(ATP binding);GO:0003824(catalytic activity);GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0006464(cellular protein modification process);GO:0016874(ligase activity);GO:0005829(cytosol);GO:0008652(cellular amino acid biosynthetic process);GO:0072590(N-acetyl-L-aspartate-L-glutamate ligase activity)","00250(Alanine, aspartate and glutamate metabolism)","K18311","EC:6.3.2.41;EC:6.3.2.42","ribosomal modification protein rimK like family member A [Source:HGNC Symbol;Acc:HGNC:28725]",{"v":0.0115556108451175,"d":"0.01"},{"v":0.0480913394944884,"d":"0.05"},{"v":0.240284653465347,"d":"0.24"},{"v":-2.05718358573068,"d":"-2.06"},1,1,"down","no"]
["MSTRG.10048","AP001434.1","ENST00000444977","NA","NA","NA","NA",null,{"v":0.295262,"d":"0.30"},{"v":0.285262,"d":"0.29"},{"v":1.03505549284517,"d":"1.04"},{"v":0.0497081175858318,"d":"0.05"},1,1,"up","no"]
["ENSG00000063660","GPC1","ENST00000495100;ENST00000469694;ENST00000420138;ENST00000264039","GO:0016020(membrane);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0005886(plasma membrane);GO:0005576(extracellular region);GO:0043236(laminin binding);GO:0005578(proteinaceous extracellular matrix);GO:0005615(extracellular space);GO:0031225(anchored component of membrane);GO:0045121(membrane raft);GO:0050900(leukocyte migration);GO:0043395(heparan sulfate proteoglycan binding);GO:0005768(endosome);GO:0070062(extracellular exosome);GO:0005887(integral component of plasma membrane);GO:0005507(copper ion binding);GO:2001016(positive regulation of skeletal muscle cell differentiation);GO:0007411(axon guidance);GO:0043202(lysosomal lumen);GO:0001523(retinoid metabolic process);GO:0006024(glycosaminoglycan biosynthetic process);GO:0006027(glycosaminoglycan catabolic process);GO:0030203(glycosaminoglycan metabolic process);GO:0005796(Golgi lumen);GO:0017134(fibroblast growth factor binding);GO:0014037(Schwann cell differentiation);GO:0030200(heparan sulfate proteoglycan catabolic process);GO:0032288(myelin assembly);GO:0040037(negative regulation of fibroblast growth factor receptor signaling pathway);GO:0040037(negative regulation of fibroblast growth factor receptor signaling pathway)","05205(Proteoglycans in cancer);05418(Fluid shear stress and atherosclerosis);05418(Fluid shear stress and atherosclerosis)","K08107","NA","glypican 1 [Source:HGNC Symbol;Acc:HGNC:4449]",{"v":0.0811982271332106,"d":"0.08"},{"v":0.0266724134438306,"d":"0.03"},{"v":3.04427746308769,"d":"3.04"},{"v":1.60609985568054,"d":"1.61"},1,1,"up","no"]
["ENSG00000236528","AL033528.2","ENST00000455431","NA","NA","NA","NA",null,{"v":0.059874,"d":"0.06"},{"v":0.08626,"d":"0.09"},{"v":0.694110827730118,"d":"0.69"},{"v":-0.526762060540315,"d":"-0.53"},1,1,"down","no"]
["ENSG00000196391","ZNF774","ENST00000379090;ENST00000560038;ENST00000354377","GO:0005634(nucleus);GO:0003676(nucleic acid binding);GO:0046872(metal ion binding);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0005515(protein binding);GO:0005515(protein binding)","NA","NA","NA","zinc finger protein 774 [Source:HGNC Symbol;Acc:HGNC:33108]",0,0,1,0,1,1,"no","no"]
["ENSG00000042304","C2orf83","ENST00000409066","GO:0006810(transport);GO:0016020(membrane);GO:0015403(thiamine uptake transmembrane transporter activity);GO:0071934(thiamine transmembrane transport)","NA","NA","NA","chromosome 2 open reading frame 83 [Source:HGNC Symbol;Acc:HGNC:25344]",0,0,1,0,1,1,"no","no"]
["ENSG00000134569","LRP4","ENST00000378623","GO:0090090(negative regulation of canonical Wnt signaling pathway);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005509(calcium ion binding);GO:0005515(protein binding);GO:0007275(multicellular organism development);GO:0016055(Wnt signaling pathway);GO:0030154(cell differentiation);GO:0030509(BMP signaling pathway);GO:0030425(dendrite);GO:0005886(plasma membrane);GO:0006897(endocytosis);GO:0048513(animal organ development);GO:0014069(postsynaptic density);GO:0042813(Wnt-activated receptor activity);GO:0009986(cell surface);GO:0030971(receptor tyrosine kinase binding);GO:0050808(synapse organization);GO:0071340(skeletal muscle acetylcholine-gated channel clustering);GO:0031594(neuromuscular junction);GO:0043025(neuronal cell body);GO:0017147(Wnt-protein binding);GO:0097060(synaptic membrane);GO:0016600(flotillin complex);GO:0034185(apolipoprotein binding);GO:0042803(protein homodimerization activity);GO:0097110(scaffold protein binding);GO:0001822(kidney development);GO:0001932(regulation of protein phosphorylation);GO:0001942(hair follicle development);GO:0008104(protein localization);GO:0009953(dorsal/ventral pattern formation);GO:0009954(proximal/distal pattern formation);GO:0030178(negative regulation of Wnt signaling pathway);GO:0030279(negative regulation of ossification);GO:0030326(embryonic limb morphogenesis);GO:0042475(odontogenesis of dentin-containing tooth);GO:0042733(embryonic digit morphogenesis);GO:0043113(receptor clustering);GO:0044332(Wnt signaling pathway involved in dorsal/ventral axis specification);GO:0048813(dendrite morphogenesis);GO:0048856(anatomical structure development);GO:0050731(positive regulation of peptidyl-tyrosine phosphorylation);GO:0050771(negative regulation of axonogenesis);GO:0051124(synaptic growth at neuromuscular junction);GO:0051290(protein heterotetramerization);GO:0060173(limb development);GO:0060828(regulation of canonical Wnt signaling pathway);GO:0097104(postsynaptic membrane assembly);GO:0097105(presynaptic membrane assembly);GO:1901631(positive regulation of presynaptic membrane organization);GO:1904395(positive regulation of skeletal muscle acetylcholine-gated channel clustering);GO:0043235(receptor complex)","NA","NA","NA","LDL receptor related protein 4 [Source:HGNC Symbol;Acc:HGNC:6696]",0,0,1,0,1,1,"no","no"]
["ENSG00000112115","IL17A","ENST00000340057","GO:0005576(extracellular region);GO:0005515(protein binding);GO:0006954(inflammatory response);GO:0005125(cytokine activity);GO:0005615(extracellular space);GO:0006955(immune response);GO:0007267(cell-cell signaling);GO:0006915(apoptotic process);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0045672(positive regulation of osteoclast differentiation);GO:0032747(positive regulation of interleukin-23 production);GO:0008219(cell death);GO:0050832(defense response to fungus);GO:0071347(cellular response to interleukin-1);GO:0072537(fibroblast activation);GO:0097398(cellular response to interleukin-17);GO:1900017(positive regulation of cytokine production involved in inflammatory response);GO:2000778(positive regulation of interleukin-6 secretion);GO:0009897(external side of plasma membrane)","04060(Cytokine-cytokine receptor interaction);04659(Th17 cell differentiation);04657(IL-17 signaling pathway);05323(Rheumatoid arthritis);05321(Inflammatiory bowel disease (IBD))","K05489","NA","interleukin 17A [Source:HGNC Symbol;Acc:HGNC:5981]",0,0,1,0,1,1,"no","no"]
["ENSG00000186204","CYP4F12","ENST00000324632;ENST00000548237;ENST00000550627;ENST00000551607;ENST00000547471;ENST00000550264;ENST00000546608;ENST00000517734","GO:0046872(metal ion binding);GO:0004497(monooxygenase activity);GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0005506(iron ion binding);GO:0016705(oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen);GO:0020037(heme binding);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005737(cytoplasm);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0070330(aromatase activity);GO:0043231(intracellular membrane-bounded organelle);GO:0016324(apical plasma membrane);GO:0031090(organelle membrane);GO:0001676(long-chain fatty acid metabolic process);GO:0019369(arachidonic acid metabolic process);GO:0003091(renal water homeostasis);GO:0019825(oxygen binding);GO:0000038(very long-chain fatty acid metabolic process);GO:0017144(drug metabolic process);GO:0055078(sodium ion homeostasis);GO:0008392(arachidonic acid epoxygenase activity);GO:0050051(leukotriene-B4 20-monooxygenase activity);GO:0003095(pressure natriuresis);GO:0019373(epoxygenase P450 pathway);GO:0036101(leukotriene B4 catabolic process);GO:0042360(vitamin E metabolic process);GO:0018685(alkane 1-monooxygenase activity);GO:0018685(alkane 1-monooxygenase activity)","NA","NA","NA","cytochrome P450 family 4 subfamily F member 12 [Source:HGNC Symbol;Acc:HGNC:18857]",{"v":0.0823639575780228,"d":"0.08"},{"v":0.0463102732199589,"d":"0.05"},{"v":1.77852454436666,"d":"1.78"},{"v":0.830680884319201,"d":"0.83"},1,1,"up","no"]
["MSTRG.6721","AC243732.1","ENST00000612648","NA","NA","NA","NA",null,0,{"v":0.23561,"d":"0.24"},"-inf","-inf",1,1,"down","no"]
["ENSG00000267296","CEBPA-AS1","ENST00000592982","NA","NA","NA","NA","CEBPA antisense RNA 1 (head to head) [Source:HGNC Symbol;Acc:HGNC:25710]",0,0,1,0,1,1,"no","no"]
["ENSG00000125675","GRIA3","ENST00000620443;ENST00000611689;ENST00000622768;ENST00000477389","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005216(ion channel activity);GO:0006811(ion transport);GO:0034220(ion transmembrane transport);GO:0005886(plasma membrane);GO:0030054(cell junction);GO:0045202(synapse);GO:0045211(postsynaptic membrane);GO:0004872(receptor activity);GO:0004970(ionotropic glutamate receptor activity);GO:0005234(extracellular-glutamate-gated ion channel activity);GO:0035235(ionotropic glutamate receptor signaling pathway);GO:0060079(excitatory postsynaptic potential);GO:0032281(AMPA glutamate receptor complex);GO:0030666(endocytic vesicle membrane);GO:0007215(glutamate receptor signaling pathway);GO:0001540(amyloid-beta binding);GO:0004971(AMPA glutamate receptor activity);GO:0005231(excitatory extracellular ligand-gated ion channel activity);GO:0005231(excitatory extracellular ligand-gated ion channel activity)","04024(cAMP signaling pathway);04080(Neuroactive ligand-receptor interaction);04724(Glutamatergic synapse);04728(Dopaminergic synapse);04730(Long-term depression);04723(Retrograde endocannabinoid signaling);04713(Circadian entrainment);05202(Transcriptional misregulation in cancers);05031(Amphetamine addiction);05033(Nicotine addiction);05033(Nicotine addiction)","K05199","NA","glutamate ionotropic receptor AMPA type subunit 3 [Source:HGNC Symbol;Acc:HGNC:4573]",0,{"v":2.18333621221468E-3,"d":"0.00"},"-inf","-inf",1,1,"down","no"]
["ENSG00000225361","PPP1R26-AS1","ENST00000603624","NA","NA","NA","NA","PPP1R26 antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:48717]",{"v":0.0424959696,"d":"0.04"},0,"inf","inf",1,1,"up","no"]
["ENSG00000230773","AC092650.1","ENST00000587616;ENST00000447571","NA","NA","NA","NA",null,{"v":0.0366319736202707,"d":"0.04"},{"v":0.00883227768136064,"d":"0.01"},{"v":4.14751154139749,"d":"4.15"},{"v":2.05224599581496,"d":"2.05"},1,1,"up","no"]
["ENSG00000217874","OR4F7P","ENST00000402444","NA","NA","NA","NA","olfactory receptor family 4 subfamily F member 7 pseudogene [Source:HGNC Symbol;Acc:HGNC:15089]",0,0,1,0,1,1,"no","no"]
["ENSG00000236980","C3orf84","ENST00000545770","NA","NA","NA","NA","chromosome 3 open reading frame 84 [Source:HGNC Symbol;Acc:HGNC:44666]",0,0,1,0,1,1,"no","no"]
["MSTRG.7370","AC124287.1","ENST00000582249","NA","NA","NA","NA",null,{"v":0.204417,"d":"0.20"},{"v":0.032297,"d":"0.03"},{"v":6.32928754992724,"d":"6.33"},{"v":2.66204311323434,"d":"2.66"},1,1,"up","no"]
["ENSG00000279151","AL021920.1","ENST00000624517","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000272842","AL391834.1","ENST00000609609","NA","NA","NA","NA",null,0,{"v":0.364115,"d":"0.36"},"-inf","-inf",1,1,"down","no"]
["ENSG00000130957","FBP2","ENST00000375337","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0005654(nucleoplasm);GO:0016787(hydrolase activity);GO:0005975(carbohydrate metabolic process);GO:0005886(plasma membrane);GO:0016791(phosphatase activity);GO:0016311(dephosphorylation);GO:0005515(protein binding);GO:0003824(catalytic activity);GO:0008152(metabolic process);GO:0030054(cell junction);GO:0042802(identical protein binding);GO:0006094(gluconeogenesis);GO:0042578(phosphoric ester hydrolase activity);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0042132(fructose 1,6-bisphosphate 1-phosphatase activity);GO:0005986(sucrose biosynthetic process);GO:0006000(fructose metabolic process);GO:0006002(fructose 6-phosphate metabolic process);GO:0030388(fructose 1,6-bisphosphate metabolic process);GO:0030018(Z disc)","00010(Glycolysis / Gluconeogenesis);00030(Pentose phosphate pathway);00051(Fructose and mannose metabolism);04152(AMPK signaling pathway);04910(Insulin signaling pathway)","K03841","EC:3.1.3.11","fructose-bisphosphatase 2 [Source:HGNC Symbol;Acc:HGNC:3607]",0,0,1,0,1,1,"no","no"]
["MSTRG.7027","TOB1-AS1","ENST00000519432;ENST00000416263","NA","NA","NA","NA","TOB1 antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:44340]",{"v":0.263304179153094,"d":"0.26"},{"v":0.244657711028385,"d":"0.24"},{"v":1.07621451229283,"d":"1.08"},{"v":0.105965666162654,"d":"0.11"},1,1,"up","no"]
["ENSG00000153266","FEZF2","ENST00000283268","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006366(transcription from RNA polymerase II promoter);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0007275(multicellular organism development);GO:0007399(nervous system development);GO:0030154(cell differentiation);GO:0045944(positive regulation of transcription from RNA polymerase II promoter)","NA","NA","NA","FEZ family zinc finger 2 [Source:HGNC Symbol;Acc:HGNC:13506]",0,0,1,0,1,1,"no","no"]
["ENSG00000204414","CSHL1","ENST00000560999","GO:0005576(extracellular region);GO:0005179(hormone activity);GO:0046872(metal ion binding);GO:0008150(biological_process);GO:0005575(cellular_component)","NA","NA","NA","chorionic somatomammotropin hormone like 1 [Source:HGNC Symbol;Acc:HGNC:2442]",0,0,1,0,1,1,"no","no"]
["MSTRG.656","DLSTP1","ENST00000444241","NA","NA","NA","NA","dihydrolipoamide S-succinyltransferase pseudogene 1 [Source:HGNC Symbol;Acc:HGNC:2912]",0,0,1,0,1,1,"no","no"]
["MSTRG.12933","AL645931.1","ENST00000439737","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["MSTRG.2782","AP000446.1","ENST00000530045","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["MSTRG.1074","PAQR6","ENST00000356983;ENST00000480773;ENST00000613336;ENST00000335852;ENST00000540423","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0043401(steroid hormone mediated signaling pathway);GO:0005886(plasma membrane);GO:0003707(steroid hormone receptor activity);GO:0005496(steroid binding);GO:0048545(response to steroid hormone);GO:0048545(response to steroid hormone)","NA","NA","NA","progestin and adipoQ receptor family member 6 [Source:HGNC Symbol;Acc:HGNC:30132]",{"v":0.220656383353834,"d":"0.22"},{"v":0.225557342353424,"d":"0.23"},{"v":0.978271782472456,"d":"0.98"},{"v":-0.0316927659533467,"d":"-0.03"},1,1,"down","no"]
["ENSG00000267560","AC027514.2","ENST00000591014","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000206090","AP000350.1","ENST00000443377","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000255760","LINC02422","ENST00000535163","NA","NA","NA","NA","long intergenic non-protein coding RNA 2422 [Source:HGNC Symbol;Acc:HGNC:53352]",{"v":0.007363,"d":"0.01"},{"v":1.775894,"d":"1.78"},{"v":0.00414608079085801,"d":"0.00"},{"v":-7.91403605547125,"d":"-7.91"},1,1,"down","no"]
["ENSG00000267496","FAM215A","ENST00000632077;ENST00000588043","NA","NA","NA","NA","family with sequence similarity 215 member A (non-protein coding) [Source:HGNC Symbol;Acc:HGNC:17505]",{"v":0.0335352916666667,"d":"0.03"},{"v":0.0642574911616162,"d":"0.06"},{"v":0.52188921572305,"d":"0.52"},{"v":-0.938184504355685,"d":"-0.94"},1,1,"down","no"]
["MSTRG.7438","STK25P1","ENST00000585406","NA","NA","NA","NA","serine/threonine kinase 25 pseudogene 1 [Source:HGNC Symbol;Acc:HGNC:50361]",0,{"v":0.18219,"d":"0.18"},"-inf","-inf",1,1,"down","no"]
["ENSG00000165171","METTL27","ENST00000297873;ENST00000458679;ENST00000493174","GO:0005515(protein binding);GO:0005515(protein binding)","NA","NA","NA","methyltransferase like 27 [Source:HGNC Symbol;Acc:HGNC:19068]",{"v":0.0875399040163377,"d":"0.09"},{"v":0.22237601565691,"d":"0.22"},{"v":0.393657129604289,"d":"0.39"},{"v":-1.34498848748295,"d":"-1.34"},1,1,"down","no"]
["ENSG00000278943","AC079228.1","ENST00000624774","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000168539","CHRM1","ENST00000306960","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0004930(G-protein coupled receptor activity);GO:0007186(G-protein coupled receptor signaling pathway);GO:0005887(integral component of plasma membrane);GO:0005886(plasma membrane);GO:0004871(signal transducer activity);GO:0007165(signal transduction);GO:0016907(G-protein coupled acetylcholine receptor activity);GO:0046541(saliva secretion);GO:0030054(cell junction);GO:0045202(synapse);GO:0045211(postsynaptic membrane);GO:0007399(nervous system development);GO:0004435(phosphatidylinositol phospholipase C activity);GO:0006464(cellular protein modification process);GO:0008283(cell proliferation);GO:0008284(positive regulation of cell proliferation);GO:0007205(protein kinase C-activating G-protein coupled receptor signaling pathway);GO:0007271(synaptic transmission, cholinergic);GO:0007197(adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway);GO:0007207(phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway);GO:0007213(G-protein coupled acetylcholine receptor signaling pathway);GO:0040012(regulation of locomotion);GO:0008144(drug binding);GO:0003056(regulation of vascular smooth muscle contraction);GO:0007274(neuromuscular synaptic transmission);GO:0043270(positive regulation of ion transport);GO:0050890(cognition);GO:0090316(positive regulation of intracellular protein transport);GO:0014069(postsynaptic density);GO:0030425(dendrite);GO:0032279(asymmetric synapse);GO:0043679(axon terminus)","04020(Calcium signaling pathway);04024(cAMP signaling pathway);04151(PI3K-Akt signaling pathway);04080(Neuroactive ligand-receptor interaction);04810(Regulation of actin cytoskeleton);04725(Cholinergic synapse)","K04129","NA","cholinergic receptor muscarinic 1 [Source:HGNC Symbol;Acc:HGNC:1950]",0,0,1,0,1,1,"no","no"]
["ENSG00000187569","DPPA3","ENST00000345088","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016569(covalent chromatin modification);GO:0007275(multicellular organism development);GO:0035064(methylated histone binding);GO:0040016(embryonic cleavage);GO:0044726(protection of DNA demethylation of female pronucleus);GO:1901536(negative regulation of DNA demethylation);GO:2000653(regulation of genetic imprinting);GO:0001939(female pronucleus)","NA","NA","NA","developmental pluripotency associated 3 [Source:HGNC Symbol;Acc:HGNC:19199]",0,{"v":0.027962,"d":"0.03"},"-inf","-inf",1,1,"down","no"]
["ENSG00000104881","PPP1R13L","ENST00000418234;ENST00000589858;ENST00000593226","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0045171(intercellular bridge);GO:0030054(cell junction);GO:0008134(transcription factor binding);GO:0006915(apoptotic process);GO:0005515(protein binding);GO:0042802(identical protein binding);GO:0005654(nucleoplasm);GO:0045296(cadherin binding);GO:0003714(transcription corepressor activity);GO:1901796(regulation of signal transduction by p53 class mediator);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0003215(cardiac right ventricle morphogenesis);GO:0003229(ventricular cardiac muscle tissue development);GO:0009791(post-embryonic development);GO:0031076(embryonic camera-type eye development);GO:0035264(multicellular organism growth);GO:0042633(hair cycle);GO:0045597(positive regulation of cell differentiation);GO:0048871(multicellular organismal homeostasis);GO:0060048(cardiac muscle contraction);GO:0060048(cardiac muscle contraction)","NA","NA","NA","protein phosphatase 1 regulatory subunit 13 like [Source:HGNC Symbol;Acc:HGNC:18838]",{"v":0.185435265103339,"d":"0.19"},{"v":0.0660294745627981,"d":"0.07"},{"v":2.8083710544596,"d":"2.81"},{"v":1.48973356351387,"d":"1.49"},1,1,"up","no"]
["ENSG00000266907","AC006116.1","ENST00000587908","NA","NA","NA","NA",null,{"v":0.023679,"d":"0.02"},{"v":0.012692,"d":"0.01"},{"v":1.86566341002206,"d":"1.87"},{"v":0.899688728690564,"d":"0.90"},1,1,"up","no"]
["ENSG00000163254","CRYGC","ENST00000282141","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0007601(visual perception);GO:0005515(protein binding);GO:0005212(structural constituent of eye lens)","NA","NA","NA","crystallin gamma C [Source:HGNC Symbol;Acc:HGNC:2410]",0,0,1,0,1,1,"no","no"]
["ENSG00000268230","AC012313.3","ENST00000599109","NA","NA","NA","NA",null,{"v":0.256714332450012,"d":"0.26"},{"v":0.120416297759576,"d":"0.12"},{"v":2.13189026092273,"d":"2.13"},{"v":1.09213317726348,"d":"1.09"},1,1,"up","no"]
["ENSG00000087085","ACHE","ENST00000302913;ENST00000619863","GO:0005634(nucleus);GO:0016020(membrane);GO:0016787(hydrolase activity);GO:0007155(cell adhesion);GO:0042803(protein homodimerization activity);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0030054(cell junction);GO:0045202(synapse);GO:0007399(nervous system development);GO:0006260(DNA replication);GO:0031225(anchored component of membrane);GO:0052689(carboxylic ester hydrolase activity);GO:0001540(amyloid-beta binding);GO:0008283(cell proliferation);GO:0007517(muscle organ development);GO:0004104(cholinesterase activity);GO:0050714(positive regulation of protein secretion);GO:0048471(perinuclear region of cytoplasm);GO:0042136(neurotransmitter biosynthetic process);GO:0005794(Golgi apparatus);GO:0009611(response to wounding);GO:0007416(synapse assembly);GO:0042982(amyloid precursor protein metabolic process);GO:0005518(collagen binding);GO:0003990(acetylcholinesterase activity);GO:0043236(laminin binding);GO:0042166(acetylcholine binding);GO:0006656(phosphatidylcholine biosynthetic process);GO:0042135(neurotransmitter catabolic process);GO:0017171(serine hydrolase activity);GO:0001507(acetylcholine catabolic process in synaptic cleft);GO:0002076(osteoblast development);GO:0006581(acetylcholine catabolic process);GO:0032223(negative regulation of synaptic transmission, cholinergic);GO:0005605(basal lamina);GO:0043083(synaptic cleft);GO:0016021(integral component of membrane);GO:0043621(protein self-association);GO:0001919(regulation of receptor recycling);GO:0031623(receptor internalization);GO:0045212(neurotransmitter receptor biosynthetic process);GO:0051262(protein tetramerization);GO:0060041(retina development in camera-type eye);GO:0005615(extracellular space);GO:0009986(cell surface);GO:0031594(neuromuscular junction);GO:0031594(neuromuscular junction)","00564(Glycerophospholipid metabolism);04725(Cholinergic synapse);04725(Cholinergic synapse)","NA","NA","acetylcholinesterase (Cartwright blood group) [Source:HGNC Symbol;Acc:HGNC:108]",{"v":0.17084903564728,"d":"0.17"},{"v":0.0681559635486465,"d":"0.07"},{"v":2.50673641383319,"d":"2.51"},{"v":1.3258103031331,"d":"1.33"},1,1,"up","no"]
["ENSG00000122585","NPY","ENST00000407573;ENST00000405982","GO:0005794(Golgi apparatus);GO:0005576(extracellular region);GO:0065009(regulation of molecular function);GO:0005179(hormone activity);GO:0007218(neuropeptide signaling pathway);GO:0005615(extracellular space);GO:0001664(G-protein coupled receptor binding);GO:0004930(G-protein coupled receptor activity);GO:0005102(receptor binding);GO:0005184(neuropeptide hormone activity);GO:0007631(feeding behavior);GO:0006928(movement of cell or subcellular component);GO:0007268(chemical synaptic transmission);GO:0008283(cell proliferation);GO:0007586(digestion);GO:0006816(calcium ion transport);GO:0008015(blood circulation);GO:0031175(neuron projection development);GO:0032098(regulation of appetite);GO:0005246(calcium channel regulator activity);GO:0007187(G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger);GO:0007610(behavior);GO:0008343(adult feeding behavior);GO:0021954(central nervous system neuron development);GO:0021987(cerebral cortex development);GO:0032100(positive regulation of appetite);GO:0005623(cell);GO:0008217(regulation of blood pressure);GO:0005737(cytoplasm);GO:0005737(cytoplasm)","04024(cAMP signaling pathway);04923(Regulation of lipolysis in adipocyte);04920(Adipocytokine signaling pathway);05034(Alcoholism);05034(Alcoholism)","NA","NA","neuropeptide Y [Source:HGNC Symbol;Acc:HGNC:7955]",0,0,1,0,1,1,"no","no"]
["ENSG00000169347","GP2","ENST00000302555","GO:0016020(membrane);GO:0005886(plasma membrane);GO:0005576(extracellular region);GO:0031225(anchored component of membrane);GO:0070062(extracellular exosome);GO:0006501(C-terminal protein lipidation)","NA","NA","NA","glycoprotein 2 [Source:HGNC Symbol;Acc:HGNC:4441]",0,0,1,0,1,1,"no","no"]
["ENSG00000230323","LINC00159","ENST00000414877","NA","NA","NA","NA","long intergenic non-protein coding RNA 159 [Source:HGNC Symbol;Acc:HGNC:1285]",0,0,1,0,1,1,"no","no"]
["ENSG00000257758","KRT18P20","ENST00000548986","NA","NA","NA","NA","keratin 18 pseudogene 20 [Source:HGNC Symbol;Acc:HGNC:33388]",0,0,1,0,1,1,"no","no"]
["ENSG00000180347","CCDC129","ENST00000319386","GO:0005102(receptor binding)","NA","NA","NA","coiled-coil domain containing 129 [Source:HGNC Symbol;Acc:HGNC:27363]",0,0,1,0,1,1,"no","no"]
["ENSG00000279452","AC006277.1","ENST00000624348","NA","NA","NA","NA",null,{"v":0.06566,"d":"0.07"},{"v":0.126439,"d":"0.13"},{"v":0.519301797704822,"d":"0.52"},{"v":-0.945354875170604,"d":"-0.95"},1,1,"down","no"]
["ENSG00000188937","NYX","ENST00000342595","GO:0005576(extracellular region);GO:0005578(proteinaceous extracellular matrix);GO:0050896(response to stimulus);GO:0005737(cytoplasm);GO:0003674(molecular_function);GO:0008150(biological_process);GO:0005622(intracellular);GO:0007601(visual perception);GO:0004860(protein kinase inhibitor activity);GO:0006469(negative regulation of protein kinase activity);GO:0019221(cytokine-mediated signaling pathway);GO:0046426(negative regulation of JAK-STAT cascade)","NA","NA","NA","nyctalopin [Source:HGNC Symbol;Acc:HGNC:8082]",0,0,1,0,1,1,"no","no"]
["ENSG00000275854","AC084824.4","ENST00000620106","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000235812","ADAM21P1","ENST00000530196;ENST00000529267","NA","NA","NA","NA","ADAM metallopeptidase domain 21 pseudogene 1 [Source:HGNC Symbol;Acc:HGNC:19822]",0,{"v":0.0430956326265686,"d":"0.04"},"-inf","-inf",1,1,"down","no"]
["ENSG00000258415","AC060814.1","ENST00000554326","NA","NA","NA","NA",null,{"v":0.049368,"d":"0.05"},0,"inf","inf",1,1,"up","no"]
["ENSG00000251688","LINC02507","ENST00000509370","NA","NA","NA","NA","long intergenic non-protein coding RNA 2507 [Source:HGNC Symbol;Acc:HGNC:53496]",0,0,1,0,1,1,"no","no"]
["ENSG00000277701","AC159540.2","ENST00000613749;ENST00000621110;ENST00000618066","NA","NA","NA","NA",null,{"v":0.0880824284316922,"d":"0.09"},{"v":0.0310442530159765,"d":"0.03"},{"v":2.83731833993112,"d":"2.84"},{"v":1.50452802642287,"d":"1.50"},1,1,"up","no"]
["ENSG00000253140","AC026904.2","ENST00000521359","NA","NA","NA","NA",null,0,{"v":0.094771,"d":"0.09"},"-inf","-inf",1,1,"down","no"]
["ENSG00000251694","USP17L9P","ENST00000508843","NA","NA","NA","NA","ubiquitin specific peptidase 17-like family member 9, pseudogene [Source:HGNC Symbol;Acc:HGNC:12615]",0,0,1,0,1,1,"no","no"]
["ENSG00000251193","AC112203.1","ENST00000506315","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000243304","AC008494.1","ENST00000497612","NA","NA","NA","NA",null,{"v":0.066733,"d":"0.07"},0,"inf","inf",1,1,"up","no"]
["ENSG00000262001","DLGAP1-AS2","ENST00000573177;ENST00000572856","NA","NA","NA","NA","DLGAP1 antisense RNA 2 [Source:HGNC Symbol;Acc:HGNC:28146]",{"v":0.104170958688111,"d":"0.10"},{"v":0.0810758520971302,"d":"0.08"},{"v":1.28485801867753,"d":"1.28"},{"v":0.361608945359272,"d":"0.36"},1,1,"up","no"]
["ENSG00000283258","AC007491.1","ENST00000637961","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["MSTRG.3482","AC137834.2","ENST00000617433","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["MSTRG.155","UBE2V2P3","ENST00000433562","NA","NA","NA","NA","ubiquitin conjugating enzyme E2 V2 pseudogene 3 [Source:HGNC Symbol;Acc:HGNC:44891]",{"v":0.094873,"d":"0.09"},{"v":0.112215,"d":"0.11"},{"v":0.845457380920554,"d":"0.85"},{"v":-0.242196063947296,"d":"-0.24"},1,1,"down","no"]
["ENSG00000271664","AC004890.3","ENST00000605566","NA","NA","NA","NA",null,{"v":0.048511,"d":"0.05"},0,"inf","inf",1,1,"up","no"]
["ENSG00000271208","Z99289.3","ENST00000605586","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["MSTRG.13501","AC006042.2","ENST00000428660","NA","NA","NA","NA",null,0,{"v":0.015724,"d":"0.02"},"-inf","-inf",1,1,"down","no"]
["ENSG00000274010","AC006011.2","ENST00000621313","NA","NA","NA","NA",null,{"v":0.045872,"d":"0.05"},0,"inf","inf",1,1,"up","no"]
["ENSG00000006611","USH1C","ENST00000005226","GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0051015(actin filament binding);GO:0007605(sensory perception of sound);GO:0005856(cytoskeleton);GO:0042995(cell projection);GO:0005515(protein binding);GO:0030154(cell differentiation);GO:0005902(microvillus);GO:0005903(brush border);GO:0005886(plasma membrane);GO:0030507(spectrin binding);GO:0045202(synapse);GO:0045494(photoreceptor cell maintenance);GO:0050953(sensory perception of light stimulus);GO:0001917(photoreceptor inner segment);GO:0051017(actin filament bundle assembly);GO:0050957(equilibrioception);GO:0043623(cellular protein complex assembly);GO:0032420(stereocilium);GO:1904970(brush border assembly);GO:1904106(protein localization to microvillus);GO:0032532(regulation of microvillus length);GO:0045177(apical part of cell);GO:0042472(inner ear morphogenesis);GO:0001750(photoreceptor outer segment);GO:0000086(G2/M transition of mitotic cell cycle);GO:0030046(parallel actin filament bundle assembly);GO:0042491(auditory receptor cell differentiation);GO:0060122(inner ear receptor stereocilium organization)","NA","NA","NA","USH1 protein network component harmonin [Source:HGNC Symbol;Acc:HGNC:12597]",0,0,1,0,1,1,"no","no"]
["ENSG00000105675","ATP4A","ENST00000262623","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0000287(magnesium ion binding);GO:0016787(hydrolase activity);GO:0006811(ion transport);GO:0006813(potassium ion transport);GO:0005886(plasma membrane);GO:0006814(sodium ion transport);GO:0005615(extracellular space);GO:0015991(ATP hydrolysis coupled proton transport);GO:0015992(proton transport);GO:0005391(sodium:potassium-exchanging ATPase activity);GO:0010248(establishment or maintenance of transmembrane electrochemical gradient);GO:0034220(ion transmembrane transport);GO:0005887(integral component of plasma membrane);GO:0008900(hydrogen:potassium-exchanging ATPase activity)","00190(Oxidative phosphorylation);04971(Gastric acid secretion);04966(Collecting duct acid secretion)","K01542","EC:3.6.3.10","ATPase H+/K+ transporting alpha subunit [Source:HGNC Symbol;Acc:HGNC:819]",0,0,1,0,1,1,"no","no"]
["ENSG00000140798","ABCC12","ENST00000528693;ENST00000311303","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0055085(transmembrane transport);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0042626(ATPase activity, coupled to transmembrane movement of substances);GO:0016887(ATPase activity);GO:0005739(mitochondrion);GO:0005739(mitochondrion)","02010(ABC transporters);02010(ABC transporters)","K05672","NA","ATP binding cassette subfamily C member 12 [Source:HGNC Symbol;Acc:HGNC:14640]",0,0,1,0,1,1,"no","no"]
["ENSG00000230960","AL109910.1","ENST00000452071","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000279628","AC131280.1","ENST00000624067","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000266777","AC090616.6","ENST00000582640","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000248364","OR7E86P","ENST00000505858","NA","NA","NA","NA","olfactory receptor family 7 subfamily E member 86 pseudogene [Source:HGNC Symbol;Acc:HGNC:14694]",0,0,1,0,1,1,"no","no"]
["MSTRG.8781","AC017083.2","ENST00000608069","NA","NA","NA","NA",null,{"v":0.054259,"d":"0.05"},{"v":0.103278,"d":"0.10"},{"v":0.525368423091075,"d":"0.53"},{"v":-0.928598604006486,"d":"-0.93"},1,1,"down","no"]
["ENSG00000139044","B4GALNT3","ENST00000266383;ENST00000535402;ENST00000322843","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005794(Golgi apparatus);GO:0043231(intracellular membrane-bounded organelle);GO:0016740(transferase activity);GO:0008376(acetylgalactosaminyltransferase activity);GO:0032580(Golgi cisterna membrane);GO:0033842(N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase activity);GO:0033842(N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase activity)","NA","NA","NA","beta-1,4-N-acetyl-galactosaminyltransferase 3 [Source:HGNC Symbol;Acc:HGNC:24137]",{"v":0.0974627280163599,"d":"0.10"},{"v":0.0164357225106182,"d":"0.02"},{"v":5.92993267885818,"d":"5.93"},{"v":2.56801572628414,"d":"2.57"},1,1,"up","no"]
["ENSG00000081479","LRP2","ENST00000263816","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0046872(metal ion binding);GO:0005509(calcium ion binding);GO:0005765(lysosomal membrane);GO:0005905(clathrin-coated pit);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0006897(endocytosis);GO:0070062(extracellular exosome);GO:0061024(membrane organization);GO:0017124(SH3 domain binding);GO:0005764(lysosome);GO:0016324(apical plasma membrane);GO:0001523(retinoid metabolic process);GO:0006629(lipid metabolic process);GO:0043235(receptor complex);GO:0042359(vitamin D metabolic process);GO:0030665(clathrin-coated vesicle membrane);GO:0006898(receptor-mediated endocytosis);GO:0005041(low-density lipoprotein receptor activity);GO:0042954(lipoprotein transporter activity);GO:0051087(chaperone binding);GO:0003281(ventricular septum development);GO:0006766(vitamin metabolic process);GO:0007507(heart development);GO:0008283(cell proliferation);GO:0030900(forebrain development);GO:0035904(aorta development);GO:0042953(lipoprotein transport);GO:0060976(coronary vasculature development);GO:0005768(endosome);GO:0005783(endoplasmic reticulum);GO:0005794(Golgi apparatus);GO:0005903(brush border);GO:0030139(endocytic vesicle);GO:0031526(brush border membrane);GO:0045177(apical part of cell)","04340(Hedgehog signaling pathway);04918(Thyroid hormone synthesis);04979(Cholesterol metabolism)","K06233","NA","LDL receptor related protein 2 [Source:HGNC Symbol;Acc:HGNC:6694]",0,0,1,0,1,1,"no","no"]
["ENSG00000265115","AC011824.1","ENST00000584863","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000205549","C9orf92","ENST00000380685","NA","NA","NA","NA","chromosome 9 open reading frame 92 [Source:HGNC Symbol;Acc:HGNC:19054]",0,0,1,0,1,1,"no","no"]
["ENSG00000242419","PCDHGC4","ENST00000617094","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005509(calcium ion binding);GO:0007155(cell adhesion);GO:0007156(homophilic cell adhesion via plasma membrane adhesion molecules);GO:0005886(plasma membrane);GO:0005887(integral component of plasma membrane);GO:0007399(nervous system development);GO:0007267(cell-cell signaling);GO:0050808(synapse organization)","NA","NA","NA","protocadherin gamma subfamily C, 4 [Source:HGNC Symbol;Acc:HGNC:8717]",{"v":0.0320386411338963,"d":"0.03"},0,"inf","inf",1,1,"up","no"]
["ENSG00000125813","PAX1","ENST00000613128;ENST00000444366","GO:0005634(nucleus);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0007275(multicellular organism development);GO:0006366(transcription from RNA polymerase II promoter);GO:0001501(skeletal system development);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:0001077(transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0001756(somitogenesis);GO:0007389(pattern specification process);GO:0008283(cell proliferation);GO:0043367(CD4-positive, alpha-beta T cell differentiation);GO:0043374(CD8-positive, alpha-beta T cell differentiation);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0048538(thymus development);GO:0060017(parathyroid gland development);GO:0060349(bone morphogenesis);GO:0061056(sclerotome development);GO:0061056(sclerotome development)","NA","NA","NA","paired box 1 [Source:HGNC Symbol;Acc:HGNC:8615]",0,0,1,0,1,1,"no","no"]
["ENSG00000271129","AC009027.1","ENST00000604510","NA","NA","NA","NA",null,{"v":0.089841,"d":"0.09"},0,"inf","inf",1,1,"up","no"]
["ENSG00000131096","PYY","ENST00000360085;ENST00000592796","GO:0005576(extracellular region);GO:0005515(protein binding);GO:0005179(hormone activity);GO:0005615(extracellular space);GO:0001664(G-protein coupled receptor binding);GO:0007186(G-protein coupled receptor signaling pathway);GO:0007267(cell-cell signaling);GO:0007631(feeding behavior);GO:0006928(movement of cell or subcellular component);GO:0008283(cell proliferation);GO:0007586(digestion);GO:0007010(cytoskeleton organization);GO:0005184(neuropeptide hormone activity);GO:0007218(neuropeptide signaling pathway);GO:0032098(regulation of appetite);GO:0032098(regulation of appetite)","04080(Neuroactive ligand-receptor interaction);04080(Neuroactive ligand-receptor interaction)","K05233","NA","peptide YY [Source:HGNC Symbol;Acc:HGNC:9748]",0,0,1,0,1,1,"no","no"]
["ENSG00000163207","IVL","ENST00000368764","GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005813(centrosome);GO:0005515(protein binding);GO:0016604(nuclear body);GO:0031424(keratinization);GO:0070062(extracellular exosome);GO:0030674(protein binding, bridging);GO:0030216(keratinocyte differentiation);GO:0005198(structural molecule activity);GO:0070268(cornification);GO:0001533(cornified envelope);GO:0018149(peptide cross-linking);GO:0010224(response to UV-B);GO:0018153(isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine)","NA","NA","NA","involucrin [Source:HGNC Symbol;Acc:HGNC:6187]",0,0,1,0,1,1,"no","no"]
["MSTRG.13732","SPDYE5","ENST00000624640;ENST00000625065","NA","04114(Oocyte meiosis);04914(Progesterone-mediated oocyte maturation);04914(Progesterone-mediated oocyte maturation)","K08694","NA","speedy/RINGO cell cycle regulator family member E5 [Source:HGNC Symbol;Acc:HGNC:35464]",{"v":0.126520229774436,"d":"0.13"},{"v":0.0558874863157895,"d":"0.06"},{"v":2.26383825995572,"d":"2.26"},{"v":1.17877088842812,"d":"1.18"},1,1,"up","no"]
["ENSG00000228212","OFD1P17","ENST00000437639","NA","NA","NA","NA","OFD1 pseudogene 17 [Source:HGNC Symbol;Acc:HGNC:1332]",0,0,1,0,1,1,"no","no"]
["MSTRG.5430","AC103739.2","ENST00000559839","NA","NA","NA","NA",null,{"v":0.025678,"d":"0.03"},0,"inf","inf",1,1,"up","no"]
["ENSG00000215840","AL592295.1","ENST00000400984","NA","NA","NA","NA",null,{"v":0.090334,"d":"0.09"},{"v":0.028404,"d":"0.03"},{"v":3.18032671454725,"d":"3.18"},{"v":1.66917498099562,"d":"1.67"},1,1,"up","no"]
["MSTRG.10196","PRAMENP","ENST00000337471;ENST00000419303","NA","NA","NA","NA","PRAME N-terminal-like, pseudogene [Source:HGNC Symbol;Acc:HGNC:34302]",{"v":0.0466176551497203,"d":"0.05"},{"v":0.129184882527147,"d":"0.13"},{"v":0.360859987931824,"d":"0.36"},{"v":-1.47048890846157,"d":"-1.47"},1,1,"down","no"]
["ENSG00000282917","AC107068.2","ENST00000634948;ENST00000634611","NA","NA","NA","NA",null,{"v":0.0832616563636363,"d":"0.08"},0,"inf","inf",1,1,"up","no"]
["ENSG00000265728","AP001099.1","ENST00000579385","NA","NA","NA","NA",null,{"v":0.093193,"d":"0.09"},0,"inf","inf",1,1,"up","no"]
["ENSG00000231549","USMG5P1","ENST00000425964","NA","NA","NA","NA","USMG5 pseudogene 1 [Source:HGNC Symbol;Acc:HGNC:31716]",0,0,1,0,1,1,"no","no"]
["ENSG00000189152","GRAPL","ENST00000583540;ENST00000344415;ENST00000577213","NA","NA","NA","NA","GRB2 related adaptor protein like [Source:HGNC Symbol;Acc:HGNC:37240]",{"v":0.226418665187377,"d":"0.23"},{"v":0.289065466962525,"d":"0.29"},{"v":0.783278153445878,"d":"0.78"},{"v":-0.352403374425351,"d":"-0.35"},1,1,"down","no"]
["ENSG00000184601","C14orf180","ENST00000557649","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005886(plasma membrane)","NA","NA","NA","chromosome 14 open reading frame 180 [Source:HGNC Symbol;Acc:HGNC:33795]",0,0,1,0,1,1,"no","no"]
["ENSG00000165379","LRFN5","ENST00000298119;ENST00000554171","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005615(extracellular space);GO:0005578(proteinaceous extracellular matrix);GO:0009986(cell surface);GO:0009986(cell surface)","NA","NA","NA","leucine rich repeat and fibronectin type III domain containing 5 [Source:HGNC Symbol;Acc:HGNC:20360]",0,0,1,0,1,1,"no","no"]
["MSTRG.14","FAM138A","ENST00000417324;ENST00000461467","NA","NA","NA","NA","family with sequence similarity 138 member A [Source:HGNC Symbol;Acc:HGNC:32334]",0,{"v":0.00850180229696472,"d":"0.01"},"-inf","-inf",1,1,"down","no"]
["ENSG00000185372","OR2V1","ENST00000329365","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0004930(G-protein coupled receptor activity);GO:0007186(G-protein coupled receptor signaling pathway);GO:0005886(plasma membrane);GO:0004871(signal transducer activity);GO:0007165(signal transduction);GO:0004984(olfactory receptor activity);GO:0007608(sensory perception of smell);GO:0050896(response to stimulus);GO:0050911(detection of chemical stimulus involved in sensory perception of smell)","04740(Olfactory transduction)","K04257","NA","olfactory receptor family 2 subfamily V member 1 [Source:HGNC Symbol;Acc:HGNC:8280]",0,0,1,0,1,1,"no","no"]
["ENSG00000180509","KCNE1","ENST00000399286;ENST00000489175;ENST00000416357;ENST00000432085;ENST00000337385;ENST00000399284","GO:0060307(regulation of ventricular cardiac muscle cell membrane repolarization);GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0006811(ion transport);GO:0005244(voltage-gated ion channel activity);GO:0005249(voltage-gated potassium channel activity);GO:0005267(potassium channel activity);GO:0006813(potassium ion transport);GO:0034765(regulation of ion transmembrane transport);GO:0071805(potassium ion transmembrane transport);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0045121(membrane raft);GO:0005764(lysosome);GO:0015459(potassium channel regulator activity);GO:0009986(cell surface);GO:0016324(apical plasma membrane);GO:0061337(cardiac conduction);GO:0030018(Z disc);GO:0006493(protein O-linked glycosylation);GO:0008076(voltage-gated potassium channel complex);GO:0007605(sensory perception of sound);GO:0086002(cardiac muscle cell action potential involved in contraction);GO:0086091(regulation of heart rate by cardiac conduction);GO:0071320(cellular response to cAMP);GO:1901381(positive regulation of potassium ion transmembrane transport);GO:0006487(protein N-linked glycosylation);GO:0005251(delayed rectifier potassium channel activity);GO:0031433(telethonin binding);GO:0086009(membrane repolarization);GO:0086013(membrane repolarization during cardiac muscle cell action potential);GO:0086008(voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization);GO:1902282(voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization);GO:0071435(potassium ion export);GO:0086005(ventricular cardiac muscle cell action potential);GO:0086011(membrane repolarization during action potential);GO:0090315(negative regulation of protein targeting to membrane);GO:0098915(membrane repolarization during ventricular cardiac muscle cell action potential);GO:1901379(regulation of potassium ion transmembrane transport);GO:1902259(regulation of delayed rectifier potassium channel activity);GO:1902260(negative regulation of delayed rectifier potassium channel activity);GO:1902260(negative regulation of delayed rectifier potassium channel activity)","04261(Adrenergic signaling in cardiomyocytes);04261(Adrenergic signaling in cardiomyocytes)","K04894","NA","potassium voltage-gated channel subfamily E regulatory subunit 1 [Source:HGNC Symbol;Acc:HGNC:6240]",{"v":0.236607328373884,"d":"0.24"},{"v":0.0896039091545598,"d":"0.09"},{"v":2.64059158363007,"d":"2.64"},{"v":1.40086117926492,"d":"1.40"},1,1,"up","no"]
["ENSG00000175509","AL078621.2","ENST00000419351","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000213373","LINC00671","ENST00000417193;ENST00000301683","NA","NA","NA","NA","long intergenic non-protein coding RNA 671 [Source:HGNC Symbol;Acc:HGNC:44339]",{"v":0.171185401015228,"d":"0.17"},{"v":0.0234851573604061,"d":"0.02"},{"v":7.28908895044627,"d":"7.29"},{"v":2.86573850607349,"d":"2.87"},1,1,"up","no"]
["MSTRG.13770","GNAT3","ENST00000398291","GO:0005737(cytoplasm);GO:0005525(GTP binding);GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0007186(G-protein coupled receptor signaling pathway);GO:0007165(signal transduction);GO:0003924(GTPase activity);GO:0004871(signal transducer activity);GO:0019001(guanyl nucleotide binding);GO:0031683(G-protein beta/gamma-subunit complex binding);GO:0007188(adenylate cyclase-modulating G-protein coupled receptor signaling pathway);GO:0005886(plasma membrane);GO:0001664(G-protein coupled receptor binding);GO:0001580(detection of chemical stimulus involved in sensory perception of bitter taste);GO:0006457(protein folding);GO:0007193(adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway);GO:0035094(response to nicotine);GO:0050909(sensory perception of taste);GO:0050913(sensory perception of bitter taste);GO:0050916(sensory perception of sweet taste);GO:0050917(sensory perception of umami taste);GO:0001669(acrosomal vesicle);GO:0001750(photoreceptor outer segment);GO:0001917(photoreceptor inner segment);GO:0005834(heterotrimeric G-protein complex);GO:0005930(axoneme);GO:0016324(apical plasma membrane);GO:0043234(protein complex)","04973(Carbohydrate digestion and absorption);04742(Taste transduction)","K19729","NA","G protein subunit alpha transducin 3 [Source:HGNC Symbol;Acc:HGNC:22800]",0,0,1,0,1,1,"no","no"]
["ENSG00000088002","SULT2B1","ENST00000323090;ENST00000597923","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0043231(intracellular membrane-bounded organelle);GO:0005829(cytosol);GO:0016740(transferase activity);GO:0006629(lipid metabolic process);GO:0005783(endoplasmic reticulum);GO:0008202(steroid metabolic process);GO:0005515(protein binding);GO:0008146(sulfotransferase activity);GO:0070062(extracellular exosome);GO:0003676(nucleic acid binding);GO:0004027(alcohol sulfotransferase activity);GO:0015485(cholesterol binding);GO:0050294(steroid sulfotransferase activity);GO:1990239(steroid hormone binding);GO:0000103(sulfate assimilation);GO:0050427(3'-phosphoadenosine 5'-phosphosulfate metabolic process);GO:0050427(3'-phosphoadenosine 5'-phosphosulfate metabolic process)","00140(Steroid hormone biosynthesis);00140(Steroid hormone biosynthesis)","K01015","EC:2.8.2.2","sulfotransferase family 2B member 1 [Source:HGNC Symbol;Acc:HGNC:11459]",{"v":9.97461481218994E-3,"d":"0.01"},{"v":0.0443739829907867,"d":"0.04"},{"v":0.224785203849313,"d":"0.22"},{"v":-2.15338101945197,"d":"-2.15"},1,1,"down","no"]
["ENSG00000280114","AL021920.2","ENST00000624828","NA","NA","NA","NA",null,{"v":0.01039,"d":"0.01"},0,"inf","inf",1,1,"up","no"]
["ENSG00000258451","AL163636.1","ENST00000554286","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000224157","HCG14","ENST00000444986","NA","NA","NA","NA","HLA complex group 14 (non-protein coding) [Source:HGNC Symbol;Acc:HGNC:18323]",{"v":0.013203,"d":"0.01"},{"v":0.086534,"d":"0.09"},{"v":0.152575866133543,"d":"0.15"},{"v":-2.71240131464797,"d":"-2.71"},1,1,"down","no"]
["MSTRG.5171","USP3-AS1","ENST00000559737;ENST00000560350;ENST00000559357;ENST00000558831","NA","NA","NA","NA","USP3 antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:44140]",{"v":0.0220656167218543,"d":"0.02"},{"v":0.0541017168874172,"d":"0.05"},{"v":0.407854278779575,"d":"0.41"},{"v":-1.29387430748002,"d":"-1.29"},1,1,"down","no"]
["ENSG00000112494","UNC93A","ENST00000230256","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005886(plasma membrane);GO:0003674(molecular_function);GO:0008150(biological_process)","NA","NA","NA","unc-93 homolog A (C. elegans) [Source:HGNC Symbol;Acc:HGNC:12570]",0,0,1,0,1,1,"no","no"]
["MSTRG.8429","KIR2DP1","ENST00000415311","NA","NA","NA","NA","killer cell immunoglobulin like receptor, two Ig domains pseudogene 1 [Source:HGNC Symbol;Acc:HGNC:16344]",{"v":0.135455,"d":"0.14"},{"v":0.087906,"d":"0.09"},{"v":1.5409073328328,"d":"1.54"},{"v":0.623780103590248,"d":"0.62"},1,1,"up","no"]
["ENSG00000269535","AC010320.4","ENST00000594379","NA","NA","NA","NA",null,{"v":0.034865,"d":"0.03"},{"v":0.005042,"d":"0.01"},{"v":6.91491471638239,"d":"6.91"},{"v":2.78971145831562,"d":"2.79"},1,1,"up","no"]
["ENSG00000231437","LINC01750","ENST00000442751;ENST00000438293","NA","NA","NA","NA","long intergenic non-protein coding RNA 1750 [Source:HGNC Symbol;Acc:HGNC:52538]",{"v":0.114878972144847,"d":"0.11"},{"v":0.162554433426184,"d":"0.16"},{"v":0.706710790493534,"d":"0.71"},{"v":-0.500808157764384,"d":"-0.50"},1,1,"down","no"]
["ENSG00000164176","EDIL3","ENST00000296591","GO:0046872(metal ion binding);GO:0005509(calcium ion binding);GO:0007155(cell adhesion);GO:0005576(extracellular region);GO:0007275(multicellular organism development);GO:0005178(integrin binding);GO:0070062(extracellular exosome);GO:0031012(extracellular matrix);GO:1903561(extracellular vesicle);GO:0010811(positive regulation of cell-substrate adhesion)","NA","NA","NA","EGF like repeats and discoidin domains 3 [Source:HGNC Symbol;Acc:HGNC:3173]",0,{"v":0.0177381951899617,"d":"0.02"},"-inf","-inf",1,1,"down","no"]
["ENSG00000128692","EIF2S2P4","ENST00000461070","NA","NA","NA","NA","eukaryotic translation initiation factor 2 subunit 2 beta pseudogene 4 [Source:HGNC Symbol;Acc:HGNC:37626]",{"v":1.629278,"d":"1.63"},0,"inf","inf",1,1,"up","no"]
["ENSG00000100053","CRYBB3","ENST00000215855","GO:0007601(visual perception);GO:0005515(protein binding);GO:0005212(structural constituent of eye lens)","NA","NA","NA","crystallin beta B3 [Source:HGNC Symbol;Acc:HGNC:2400]",0,0,1,0,1,1,"no","no"]
["ENSG00000010310","GIPR","ENST00000588816;ENST00000591322;ENST00000591224;ENST00000590918","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0004930(G-protein coupled receptor activity);GO:0007186(G-protein coupled receptor signaling pathway);GO:0005886(plasma membrane);GO:0004871(signal transducer activity);GO:0007165(signal transduction);GO:0004888(transmembrane signaling receptor activity);GO:0007166(cell surface receptor signaling pathway);GO:0016519(gastric inhibitory peptide receptor activity);GO:0038192(gastric inhibitory peptide signaling pathway);GO:0006091(generation of precursor metabolites and energy);GO:0007584(response to nutrient);GO:0007190(activation of adenylate cyclase activity);GO:0050796(regulation of insulin secretion);GO:0017046(peptide hormone binding);GO:0002029(desensitization of G-protein coupled receptor protein signaling pathway);GO:0007204(positive regulation of cytosolic calcium ion concentration);GO:0009749(response to glucose);GO:0030819(positive regulation of cAMP biosynthetic process);GO:0031018(endocrine pancreas development);GO:0032024(positive regulation of insulin secretion);GO:0048678(response to axon injury);GO:0051592(response to calcium ion);GO:0070542(response to fatty acid);GO:0070542(response to fatty acid)","04024(cAMP signaling pathway);04080(Neuroactive ligand-receptor interaction);04080(Neuroactive ligand-receptor interaction)","K04580","NA","gastric inhibitory polypeptide receptor [Source:HGNC Symbol;Acc:HGNC:4271]",{"v":0.227969205658784,"d":"0.23"},{"v":0.109397696579392,"d":"0.11"},{"v":2.08385745574947,"d":"2.08"},{"v":1.05925659483487,"d":"1.06"},1,1,"up","no"]
["ENSG00000215454","KRTAP10-4","ENST00000400374","GO:0005515(protein binding);GO:0005882(intermediate filament);GO:0045095(keratin filament);GO:0005829(cytosol);GO:0031424(keratinization)","NA","NA","NA","keratin associated protein 10-4 [Source:HGNC Symbol;Acc:HGNC:20521]",0,0,1,0,1,1,"no","no"]
["ENSG00000165623","UCMA","ENST00000378681","GO:0005576(extracellular region);GO:0005578(proteinaceous extracellular matrix);GO:0045667(regulation of osteoblast differentiation);GO:0045668(negative regulation of osteoblast differentiation);GO:0005615(extracellular space);GO:0016235(aggresome);GO:0048471(perinuclear region of cytoplasm)","NA","NA","NA","upper zone of growth plate and cartilage matrix associated [Source:HGNC Symbol;Acc:HGNC:25205]",0,0,1,0,1,1,"no","no"]
["ENSG00000234139","AL035420.1","ENST00000450129","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["MSTRG.14902","MIR4668","ENST00000582284","NA","NA","NA","NA","microRNA 4668 [Source:HGNC Symbol;Acc:HGNC:41545]",{"v":0.017589,"d":"0.02"},{"v":0.00963,"d":"0.01"},{"v":1.82647975077882,"d":"1.83"},{"v":0.869065759386808,"d":"0.87"},1,1,"up","no"]
["MSTRG.2173","UBQLNL","ENST00000380184","NA","NA","NA","NA","ubiquilin like [Source:HGNC Symbol;Acc:HGNC:28294]",0,{"v":0.022002,"d":"0.02"},"-inf","-inf",1,1,"down","no"]
["ENSG00000249259","AC027613.1","ENST00000513136","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000238063","LINC01685","ENST00000634732","NA","NA","NA","NA","long intergenic non-protein coding RNA 1685 [Source:HGNC Symbol;Acc:HGNC:52473]",0,0,1,0,1,1,"no","no"]
["ENSG00000152782","PANK1","ENST00000461829;ENST00000307534","GO:0005737(cytoplasm);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0004594(pantothenate kinase activity);GO:0015937(coenzyme A biosynthetic process);GO:0005829(cytosol);GO:0009108(coenzyme biosynthetic process);GO:0005634(nucleus);GO:0030118(clathrin coat);GO:0055037(recycling endosome);GO:0071944(cell periphery);GO:0071944(cell periphery)","00770(Pantothenate and CoA biosynthesis);00770(Pantothenate and CoA biosynthesis)","K09680","EC:2.7.1.33","pantothenate kinase 1 [Source:HGNC Symbol;Acc:HGNC:8598]",{"v":0.133750429300864,"d":"0.13"},{"v":0.0642207702278083,"d":"0.06"},{"v":2.08266622817533,"d":"2.08"},{"v":1.05843164900905,"d":"1.06"},1,1,"up","no"]
["ENSG00000182489","XKRX","ENST00000372956","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005886(plasma membrane)","NA","NA","NA","XK related, X-linked [Source:HGNC Symbol;Acc:HGNC:29845]",{"v":0.189120037959668,"d":"0.19"},{"v":0.128056113879004,"d":"0.13"},{"v":1.47685285950783,"d":"1.48"},{"v":0.562526095951857,"d":"0.56"},1,1,"up","no"]
["ENSG00000160188","RSPH1","ENST00000493019;ENST00000291536","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0031514(motile cilium);GO:0005829(cytosol);GO:0042995(cell projection);GO:0005515(protein binding);GO:0051321(meiotic cell cycle);GO:0005929(cilium);GO:0035082(axoneme assembly);GO:0007286(spermatid development);GO:0000794(condensed nuclear chromosome);GO:0001520(outer dense fiber);GO:0036126(sperm flagellum);GO:0072687(meiotic spindle);GO:0072687(meiotic spindle)","NA","NA","NA","radial spoke head 1 homolog [Source:HGNC Symbol;Acc:HGNC:12371]",{"v":0.0355551974564926,"d":"0.04"},{"v":0.0170322891566265,"d":"0.02"},{"v":2.08751725205767,"d":"2.09"},{"v":1.0617881206311,"d":"1.06"},1,1,"up","no"]
["ENSG00000134115","CNTN6","ENST00000446702","GO:0016020(membrane);GO:0007155(cell adhesion);GO:0005886(plasma membrane);GO:0007399(nervous system development);GO:0005112(Notch binding);GO:0022008(neurogenesis);GO:0030182(neuron differentiation);GO:0045747(positive regulation of Notch signaling pathway);GO:0007219(Notch signaling pathway);GO:0031225(anchored component of membrane);GO:0007417(central nervous system development);GO:0016021(integral component of membrane)","NA","NA","NA","contactin 6 [Source:HGNC Symbol;Acc:HGNC:2176]",0,0,1,0,1,1,"no","no"]
["ENSG00000275340","FGD5P1","ENST00000611158","NA","NA","NA","NA","FYVE, RhoGEF and PH domain containing 5 pseudogene 1 [Source:HGNC Symbol;Acc:HGNC:44498]",{"v":0.0137297120703024,"d":"0.01"},0,"inf","inf",1,1,"up","no"]
["MSTRG.380","AL033529.1;ZBTB8A;ZBTB8B","ENST00000480336;ENST00000373510;ENST00000609129","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0003674(molecular_function);GO:0008150(biological_process);GO:0005575(cellular_component);GO:0003677(DNA binding)","NA","NA","NA","zinc finger and BTB domain containing 8A [Source:HGNC Symbol;Acc:HGNC:24172];zinc finger and BTB domain containing 8B [Source:HGNC Symbol;Acc:HGNC:37057]",{"v":0.0131391348163631,"d":"0.01"},{"v":0.0114049682492286,"d":"0.01"},{"v":1.15205360762419,"d":"1.15"},{"v":0.204207850160564,"d":"0.20"},1,1,"up","no"]
["ENSG00000129965","INS-IGF2","ENST00000356578","GO:0005576(extracellular region);GO:0005179(hormone activity)","04014(Ras signaling pathway);04010(MAPK signaling pathway);04151(PI3K-Akt signaling pathway);05200(Pathways in cancer);05205(Proteoglycans in cancer);05225(Hepatocellular carcinoma)","NA","NA","INS-IGF2 readthrough [Source:HGNC Symbol;Acc:HGNC:33527]",0,0,1,0,1,1,"no","no"]
["MSTRG.15257","INE1","ENST00000456273","NA","NA","NA","NA","inactivation escape 1 (non-protein coding) [Source:HGNC Symbol;Acc:HGNC:6060]",{"v":0.139944,"d":"0.14"},0,"inf","inf",1,1,"up","no"]
["ENSG00000282997","AL162456.1","ENST00000634535","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000162849","KIF26B","ENST00000479506;ENST00000366518;ENST00000407071","GO:0005737(cytoplasm);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0003777(microtubule motor activity);GO:0005856(cytoskeleton);GO:0008017(microtubule binding);GO:0007275(multicellular organism development);GO:0005874(microtubule);GO:0005871(kinesin complex);GO:0022409(positive regulation of cell-cell adhesion);GO:0030010(establishment of cell polarity);GO:0072092(ureteric bud invasion);GO:0003774(motor activity);GO:0007018(microtubule-based movement);GO:0007018(microtubule-based movement)","NA","NA","NA","kinesin family member 26B [Source:HGNC Symbol;Acc:HGNC:25484]",{"v":0.0352810152745956,"d":"0.04"},{"v":0.0176787733805457,"d":"0.02"},{"v":1.995670995671,"d":"2.00"},{"v":0.996873899013283,"d":"1.00"},1,1,"up","no"]
["ENSG00000136866","ZFP37","ENST00000374227;ENST00000555206","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0005622(intracellular);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0008270(zinc ion binding);GO:0008270(zinc ion binding)","NA","NA","NA","ZFP37 zinc finger protein [Source:HGNC Symbol;Acc:HGNC:12863]",{"v":0.0287064390934844,"d":"0.03"},{"v":0.193755289423985,"d":"0.19"},{"v":0.148158221532046,"d":"0.15"},{"v":-2.75478940895666,"d":"-2.75"},1,1,"down","no"]
["ENSG00000145888","GLRA1","ENST00000274576","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0046872(metal ion binding);GO:0005216(ion channel activity);GO:0006811(ion transport);GO:0005887(integral component of plasma membrane);GO:0008270(zinc ion binding);GO:0005886(plasma membrane);GO:0042995(cell projection);GO:0030054(cell junction);GO:0045202(synapse);GO:0045211(postsynaptic membrane);GO:0005254(chloride channel activity);GO:0006821(chloride transport);GO:0034707(chloride channel complex);GO:0007218(neuropeptide signaling pathway);GO:0005230(extracellular ligand-gated ion channel activity);GO:0030425(dendrite);GO:0060079(excitatory postsynaptic potential);GO:0005515(protein binding);GO:0071230(cellular response to amino acid stimulus);GO:0043204(perikaryon);GO:0043231(intracellular membrane-bounded organelle);GO:0034220(ion transmembrane transport);GO:2000344(positive regulation of acrosome reaction);GO:0016594(glycine binding);GO:0022824(transmitter-gated ion channel activity);GO:0043005(neuron projection);GO:0043025(neuronal cell body);GO:0016934(extracellular-glycine-gated chloride channel activity);GO:0060012(synaptic transmission, glycinergic);GO:1902476(chloride transmembrane transport);GO:0042391(regulation of membrane potential);GO:0071294(cellular response to zinc ion);GO:0006936(muscle contraction);GO:0030977(taurine binding);GO:0001964(startle response);GO:0051970(negative regulation of transmission of nerve impulse);GO:0060080(inhibitory postsynaptic potential);GO:0071361(cellular response to ethanol);GO:0097305(response to alcohol);GO:0016933(extracellular-glycine-gated ion channel activity);GO:0001508(action potential);GO:0002087(regulation of respiratory gaseous exchange by neurological system process);GO:0006820(anion transport);GO:0007268(chemical synaptic transmission);GO:0007340(acrosome reaction);GO:0007601(visual perception);GO:0007628(adult walking behavior);GO:0043576(regulation of respiratory gaseous exchange);GO:0050884(neuromuscular process controlling posture);GO:0050905(neuromuscular process);GO:0051260(protein homooligomerization);GO:0051291(protein heterooligomerization);GO:0060013(righting reflex);GO:0005622(intracellular);GO:0005783(endoplasmic reticulum);GO:0009897(external side of plasma membrane);GO:0060077(inhibitory synapse)","04080(Neuroactive ligand-receptor interaction)","K05193","NA","glycine receptor alpha 1 [Source:HGNC Symbol;Acc:HGNC:4326]",{"v":0.0436483040262942,"d":"0.04"},0,"inf","inf",1,1,"up","no"]
["MSTRG.11745","AP002026.1","ENST00000500358;ENST00000506454;ENST00000506160;ENST00000499178","NA","NA","NA","NA",null,{"v":0.0765256470588235,"d":"0.08"},{"v":0.0612760189431705,"d":"0.06"},{"v":1.24886780144441,"d":"1.25"},{"v":0.320620768943768,"d":"0.32"},1,1,"up","no"]
["MSTRG.14547","RNF139-AS1","ENST00000499418;ENST00000530778","NA","NA","NA","NA","RNF139 antisense RNA 1 (head to head) [Source:HGNC Symbol;Acc:HGNC:48940]",{"v":0.0534796900475299,"d":"0.05"},{"v":0.179122429209276,"d":"0.18"},{"v":0.298565011001762,"d":"0.30"},{"v":-1.74388298973616,"d":"-1.74"},1,1,"down","no"]
["ENSG00000282600","AC245369.7","ENST00000631386","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000268089","GABRQ","ENST00000598523","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005216(ion channel activity);GO:0006811(ion transport);GO:0005886(plasma membrane);GO:0030054(cell junction);GO:0045202(synapse);GO:0045211(postsynaptic membrane);GO:0005254(chloride channel activity);GO:0006821(chloride transport);GO:0034707(chloride channel complex);GO:1902476(chloride transmembrane transport);GO:0004890(GABA-A receptor activity);GO:0005230(extracellular ligand-gated ion channel activity);GO:0034220(ion transmembrane transport);GO:0005887(integral component of plasma membrane);GO:1902711(GABA-A receptor complex);GO:0007165(signal transduction);GO:0004888(transmembrane signaling receptor activity);GO:0043235(receptor complex);GO:0005326(neurotransmitter transporter activity);GO:0006836(neurotransmitter transport)","04080(Neuroactive ligand-receptor interaction);04727(GABAergic synapse);04723(Retrograde endocannabinoid signaling);05032(Morphine addiction);05033(Nicotine addiction)","K05192","NA","gamma-aminobutyric acid type A receptor theta subunit [Source:HGNC Symbol;Acc:HGNC:14454]",0,0,1,0,1,1,"no","no"]
["ENSG00000180269","GPR139","ENST00000570682","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0004930(G-protein coupled receptor activity);GO:0007186(G-protein coupled receptor signaling pathway);GO:0005886(plasma membrane);GO:0004871(signal transducer activity);GO:0007165(signal transduction);GO:0007218(neuropeptide signaling pathway);GO:0008188(neuropeptide receptor activity);GO:0046983(protein dimerization activity);GO:0007200(phospholipase C-activating G-protein coupled receptor signaling pathway)","NA","NA","NA","G protein-coupled receptor 139 [Source:HGNC Symbol;Acc:HGNC:19995]",0,0,1,0,1,1,"no","no"]
["ENSG00000231615","AL645568.2","ENST00000432815","NA","NA","NA","NA",null,0,{"v":0.113941,"d":"0.11"},"-inf","-inf",1,1,"down","no"]
["ENSG00000147127","RAB41","ENST00000374473;ENST00000509895","GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005525(GTP binding);GO:0000166(nucleotide binding);GO:0003924(GTPase activity);GO:0005515(protein binding);GO:0006891(intra-Golgi vesicle-mediated transport);GO:0005794(Golgi apparatus);GO:0042147(retrograde transport, endosome to Golgi);GO:0000139(Golgi membrane);GO:0006890(retrograde vesicle-mediated transport, Golgi to ER);GO:0006890(retrograde vesicle-mediated transport, Golgi to ER)","NA","NA","NA","RAB41, member RAS oncogene family [Source:HGNC Symbol;Acc:HGNC:18293]",{"v":0.0477690267857143,"d":"0.05"},{"v":0.175227037946429,"d":"0.18"},{"v":0.272612191277915,"d":"0.27"},{"v":-1.87507801365801,"d":"-1.88"},1,1,"down","no"]
["ENSG00000233966","UBE2SP1","ENST00000450587","NA","NA","NA","NA","ubiquitin conjugating enzyme E2 S pseudogene 1 [Source:HGNC Symbol;Acc:HGNC:30864]",{"v":0.118314,"d":"0.12"},0,"inf","inf",1,1,"up","no"]
["ENSG00000228071","RPL7P47","ENST00000497299","NA","NA","NA","NA","ribosomal protein L7 pseudogene 47 [Source:HGNC Symbol;Acc:HGNC:35913]",{"v":0.054919,"d":"0.05"},{"v":0.079813,"d":"0.08"},{"v":0.688095924222871,"d":"0.69"},{"v":-0.5393183965965,"d":"-0.54"},1,1,"down","no"]
["ENSG00000230116","AL445669.1","ENST00000426743","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000269067","ZNF728","ENST00000594710","GO:0003676(nucleic acid binding);GO:0046872(metal ion binding);GO:0006355(regulation of transcription, DNA-templated);GO:0005622(intracellular);GO:0003700(transcription factor activity, sequence-specific DNA binding)","NA","NA","NA","zinc finger protein 728 [Source:HGNC Symbol;Acc:HGNC:32463]",0,0,1,0,1,1,"no","no"]
["MSTRG.5609","GLIS2","ENST00000262366","GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0043433(negative regulation of sequence-specific DNA binding transcription factor activity);GO:0005634(nucleus);GO:0003676(nucleic acid binding);GO:0005737(cytoplasm);GO:0016607(nuclear speck);GO:0046872(metal ion binding);GO:0006366(transcription from RNA polymerase II promoter);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0007275(multicellular organism development);GO:0007399(nervous system development);GO:0030154(cell differentiation);GO:0045893(positive regulation of transcription, DNA-templated);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0045892(negative regulation of transcription, DNA-templated);GO:0044212(transcription regulatory region DNA binding);GO:0001077(transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0045879(negative regulation of smoothened signaling pathway);GO:0000977(RNA polymerase II regulatory region sequence-specific DNA binding);GO:0001822(kidney development);GO:0060994(regulation of transcription from RNA polymerase II promoter involved in kidney development);GO:0061005(cell differentiation involved in kidney development);GO:1900182(positive regulation of protein localization to nucleus);GO:0097730(non-motile cilium)","NA","NA","NA","GLIS family zinc finger 2 [Source:HGNC Symbol;Acc:HGNC:29450]",{"v":0.27612,"d":"0.28"},{"v":0.011388,"d":"0.01"},{"v":24.2465753424657,"d":"24.25"},{"v":4.59970908609034,"d":"4.60"},1,1,"up","no"]
["MSTRG.8281","AC011466.2","ENST00000594589","NA","NA","NA","NA",null,0,{"v":0.019715,"d":"0.02"},"-inf","-inf",1,1,"down","no"]
["ENSG00000229196","AC087071.1","ENST00000469264;ENST00000470348","NA","NA","NA","NA",null,{"v":0.211212196819085,"d":"0.21"},{"v":0.202017940357853,"d":"0.20"},{"v":1.04551207900123,"d":"1.05"},{"v":0.0642097297558095,"d":"0.06"},1,1,"up","no"]
["ENSG00000188730","VWC2","ENST00000340652","GO:0005576(extracellular region);GO:0005578(proteinaceous extracellular matrix);GO:0030054(cell junction);GO:0045202(synapse);GO:0005604(basement membrane);GO:0005615(extracellular space);GO:0003674(molecular_function);GO:0010811(positive regulation of cell-substrate adhesion);GO:0030514(negative regulation of BMP signaling pathway);GO:0045666(positive regulation of neuron differentiation);GO:0005614(interstitial matrix);GO:0032281(AMPA glutamate receptor complex)","NA","NA","NA","von Willebrand factor C domain containing 2 [Source:HGNC Symbol;Acc:HGNC:30200]",0,0,1,0,1,1,"no","no"]
["ENSG00000021645","NRXN3","ENST00000281127;ENST00000556003;ENST00000335750;ENST00000554738;ENST00000635466","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0007269(neurotransmitter secretion);GO:0051965(positive regulation of synapse assembly);GO:0098793(presynapse);GO:0007268(chemical synaptic transmission);GO:0007416(synapse assembly);GO:0090129(positive regulation of synapse maturation);GO:0046872(metal ion binding);GO:0007155(cell adhesion);GO:0005886(plasma membrane);GO:0005887(integral component of plasma membrane);GO:0004872(receptor activity);GO:0007411(axon guidance);GO:0050839(cell adhesion molecule binding);GO:0007612(learning);GO:0035176(social behavior);GO:0097109(neuroligin family protein binding);GO:0007158(neuron cell-cell adhesion);GO:0030534(adult behavior);GO:0071625(vocalization behavior);GO:0065009(regulation of molecular function);GO:0005246(calcium channel regulator activity);GO:0043234(protein complex);GO:0001525(angiogenesis);GO:0007165(signal transduction);GO:0004888(transmembrane signaling receptor activity);GO:0004888(transmembrane signaling receptor activity)","04514(Cell adhesion molecules (CAMs));04514(Cell adhesion molecules (CAMs))","K07377","NA","neurexin 3 [Source:HGNC Symbol;Acc:HGNC:8010]",0,0,1,0,1,1,"no","no"]
["ENSG00000259425","AC011767.1","ENST00000560434","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000119227","PIGZ","ENST00000238138;ENST00000412723","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016740(transferase activity);GO:0016757(transferase activity, transferring glycosyl groups);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0097502(mannosylation);GO:0006506(GPI anchor biosynthetic process);GO:0000026(alpha-1,2-mannosyltransferase activity);GO:0000030(mannosyltransferase activity);GO:0000030(mannosyltransferase activity)","00563(Glycosylphosphatidylinositol(GPI)-anchor biosynthesis);00563(Glycosylphosphatidylinositol(GPI)-anchor biosynthesis)","K08098","EC:2.4.1.-","phosphatidylinositol glycan anchor biosynthesis class Z [Source:HGNC Symbol;Acc:HGNC:30596]",{"v":0.157049985674245,"d":"0.16"},{"v":0.0920745748987854,"d":"0.09"},{"v":1.70568244107437,"d":"1.71"},{"v":0.770349074949173,"d":"0.77"},1,1,"up","no"]
["ENSG00000107187","LHX3","ENST00000371748;ENST00000619587","GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006355(regulation of transcription, DNA-templated);GO:0006366(transcription from RNA polymerase II promoter);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0043565(sequence-specific DNA binding);GO:0045893(positive regulation of transcription, DNA-templated);GO:0001228(transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:0001076(transcription factor activity, RNA polymerase II transcription factor binding);GO:0001077(transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0001890(placenta development);GO:0008045(motor neuron axon guidance);GO:0009953(dorsal/ventral pattern formation);GO:0021520(spinal cord motor neuron cell fate specification);GO:0021521(ventral spinal cord interneuron specification);GO:0021526(medial motor column neuron differentiation);GO:0021527(spinal cord association neuron differentiation);GO:0021983(pituitary gland development);GO:0030154(cell differentiation);GO:0030324(lung development);GO:0043066(negative regulation of apoptotic process);GO:0005622(intracellular);GO:0005667(transcription factor complex);GO:0009887(animal organ morphogenesis);GO:0048839(inner ear development);GO:0001085(RNA polymerase II transcription factor binding);GO:0001085(RNA polymerase II transcription factor binding)","NA","NA","NA","LIM homeobox 3 [Source:HGNC Symbol;Acc:HGNC:6595]",0,0,1,0,1,1,"no","no"]
["ENSG00000144488","ESPNL","ENST00000343063","GO:0005737(cytoplasm);GO:0051015(actin filament binding);GO:0031941(filamentous actin);GO:0051017(actin filament bundle assembly)","NA","NA","NA","espin like [Source:HGNC Symbol;Acc:HGNC:27937]",{"v":0.0396268802685565,"d":"0.04"},{"v":0.047456293920179,"d":"0.05"},{"v":0.835018434756168,"d":"0.84"},{"v":-0.260120046477052,"d":"-0.26"},1,1,"down","no"]
["ENSG00000184302","SIX6","ENST00000327720","GO:0005634(nucleus);GO:0006355(regulation of transcription, DNA-templated);GO:0006366(transcription from RNA polymerase II promoter);GO:0003677(DNA binding);GO:0000981(RNA polymerase II transcription factor activity, sequence-specific DNA binding);GO:0007275(multicellular organism development);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0001654(eye development);GO:0007601(visual perception);GO:0009887(animal organ morphogenesis);GO:0001205(transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding)","NA","NA","NA","SIX homeobox 6 [Source:HGNC Symbol;Acc:HGNC:10892]",0,0,1,0,1,1,"no","no"]
["ENSG00000147378","FATE1","ENST00000370350","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005739(mitochondrion);GO:0005515(protein binding);GO:0006915(apoptotic process);GO:0005741(mitochondrial outer membrane);GO:0031625(ubiquitin protein ligase binding);GO:0043066(negative regulation of apoptotic process);GO:0051562(negative regulation of mitochondrial calcium ion concentration);GO:0044233(ER-mitochondrion membrane contact site)","NA","NA","NA","fetal and adult testis expressed 1 [Source:HGNC Symbol;Acc:HGNC:24683]",0,0,1,0,1,1,"no","no"]
["ENSG00000112238","PRDM13","ENST00000369214","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0008168(methyltransferase activity);GO:0016740(transferase activity);GO:0032259(methylation);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0016571(histone methylation);GO:0003682(chromatin binding);GO:0042054(histone methyltransferase activity);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0022008(neurogenesis)","NA","NA","NA","PR/SET domain 13 [Source:HGNC Symbol;Acc:HGNC:13998]",0,0,1,0,1,1,"no","no"]
["ENSG00000185155","MIXL1","ENST00000366810","GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0005634(nucleus);GO:0006355(regulation of transcription, DNA-templated);GO:0006366(transcription from RNA polymerase II promoter);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0043565(sequence-specific DNA binding);GO:0007275(multicellular organism development);GO:0030154(cell differentiation);GO:0048565(digestive tract development);GO:0042803(protein homodimerization activity);GO:0000790(nuclear chromatin);GO:0001085(RNA polymerase II transcription factor binding);GO:0000980(RNA polymerase II distal enhancer sequence-specific DNA binding);GO:0007507(heart development);GO:0001103(RNA polymerase II repressing transcription factor binding);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:0001190(transcriptional activator activity, RNA polymerase II transcription factor binding);GO:0000987(core promoter proximal region sequence-specific DNA binding);GO:0001077(transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0001205(transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding);GO:0007369(gastrulation);GO:0035987(endodermal cell differentiation);GO:0002244(hematopoietic progenitor cell differentiation);GO:0007492(endoderm development);GO:0042802(identical protein binding);GO:0001706(endoderm formation);GO:0030097(hemopoiesis);GO:0042074(cell migration involved in gastrulation);GO:1901533(negative regulation of hematopoietic progenitor cell differentiation);GO:2000382(positive regulation of mesoderm development)","NA","NA","NA","Mix paired-like homeobox [Source:HGNC Symbol;Acc:HGNC:13363]",{"v":0.104721476096599,"d":"0.10"},{"v":0.0688518383440118,"d":"0.07"},{"v":1.52096848269131,"d":"1.52"},{"v":0.604990258035417,"d":"0.60"},1,1,"up","no"]
["ENSG00000177558","FAM187B","ENST00000324675","GO:0016020(membrane);GO:0016021(integral component of membrane)","NA","NA","NA","family with sequence similarity 187 member B [Source:HGNC Symbol;Acc:HGNC:26366]",0,0,1,0,1,1,"no","no"]
["MSTRG.1685","ZNF22","ENST00000298299","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0008270(zinc ion binding);GO:0042476(odontogenesis)","NA","NA","NA","zinc finger protein 22 [Source:HGNC Symbol;Acc:HGNC:13012]",{"v":8.174595,"d":"8.17"},{"v":0.129409,"d":"0.13"},{"v":63.1686745125919,"d":"63.17"},{"v":5.98113739491678,"d":"5.98"},1,1,"up","no"]
["ENSG00000215343","ZNF705D","ENST00000400085","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0005622(intracellular)","NA","NA","NA","zinc finger protein 705D [Source:HGNC Symbol;Acc:HGNC:33202]",0,0,1,0,1,1,"no","no"]
["ENSG00000235979","AC004448.4","ENST00000582654","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000278937","AL137141.1","ENST00000624622","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000258834","DUX4L4","ENST00000566884","NA","NA","NA","NA","double homeobox 4 like 4 [Source:HGNC Symbol;Acc:HGNC:38686]",0,0,1,0,1,1,"no","no"]
["ENSG00000229887","HNRNPA1P6","ENST00000631770;ENST00000394002","NA","NA","NA","NA","heterogeneous nuclear ribonucleoprotein A1 pseudogene 6 [Source:HGNC Symbol;Acc:HGNC:5032]",0,0,1,0,1,1,"no","no"]
["ENSG00000140465","CYP1A1","ENST00000379727","GO:0016020(membrane);GO:0046872(metal ion binding);GO:0004497(monooxygenase activity);GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005506(iron ion binding);GO:0016705(oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen);GO:0005515(protein binding);GO:0020037(heme binding);GO:0016712(oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen);GO:0070330(aromatase activity);GO:0070988(demethylation);GO:0003824(catalytic activity);GO:0008395(steroid hydroxylase activity);GO:0016679(oxidoreductase activity, acting on diphenols and related substances as donors);GO:0016711(flavonoid 3'-monooxygenase activity);GO:0019899(enzyme binding);GO:0032451(demethylase activity);GO:0001666(response to hypoxia);GO:0001889(liver development);GO:0006778(porphyrin-containing compound metabolic process);GO:0007568(aging);GO:0008283(cell proliferation);GO:0009308(amine metabolic process);GO:0009404(toxin metabolic process);GO:0009611(response to wounding);GO:0009615(response to virus);GO:0009624(response to nematode);GO:0009635(response to herbicide);GO:0009636(response to toxic substance);GO:0009804(coumarin metabolic process);GO:0009812(flavonoid metabolic process);GO:0010033(response to organic substance);GO:0010041(response to iron(III) ion);GO:0014070(response to organic cyclic compound);GO:0017143(insecticide metabolic process);GO:0018894(dibenzo-p-dioxin metabolic process);GO:0019341(dibenzo-p-dioxin catabolic process);GO:0032094(response to food);GO:0032496(response to lipopolysaccharide);GO:0032502(developmental process);GO:0033189(response to vitamin A);GO:0035902(response to immobilization stress);GO:0042493(response to drug);GO:0042904(9-cis-retinoic acid biosynthetic process);GO:0043010(camera-type eye development);GO:0046483(heterocycle metabolic process);GO:0046677(response to antibiotic);GO:0046685(response to arsenic-containing substance);GO:0048565(digestive tract development);GO:0050665(hydrogen peroxide biosynthetic process);GO:0055093(response to hyperoxia);GO:0060137(maternal process involved in parturition);GO:0070365(hepatocyte differentiation);GO:0071280(cellular response to copper ion);GO:1900087(positive regulation of G1/S transition of mitotic cell cycle);GO:0005737(cytoplasm);GO:0005739(mitochondrion);GO:0043231(intracellular membrane-bounded organelle);GO:0031090(organelle membrane);GO:0019216(regulation of lipid metabolic process);GO:0042359(vitamin D metabolic process);GO:0019825(oxygen binding);GO:0070576(vitamin D 24-hydroxylase activity);GO:0101020(estrogen 16-alpha-hydroxylase activity);GO:0002933(lipid hydroxylation);GO:0008202(steroid metabolic process);GO:0009692(ethylene metabolic process);GO:0017144(drug metabolic process);GO:0019373(epoxygenase P450 pathway);GO:0071407(cellular response to organic cyclic compound);GO:0097267(omega-hydroxylase P450 pathway)","00140(Steroid hormone biosynthesis);00380(Tryptophan metabolism);00830(Retinol metabolism);00980(Metabolism of xenobiotics by cytochrome P450);04913(Ovarian Steroidogenesis);05204(Chemical carcinogenesis)","K07408","EC:1.14.14.1","cytochrome P450 family 1 subfamily A member 1 [Source:HGNC Symbol;Acc:HGNC:2595]",{"v":0.0154643493449782,"d":"0.02"},{"v":0.0132600698689956,"d":"0.01"},{"v":1.16623437868428,"d":"1.17"},{"v":0.22185775679351,"d":"0.22"},1,1,"up","no"]
["MSTRG.14005","AC083880.1","ENST00000608266","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["MSTRG.7511","AC120349.1","ENST00000599498","NA","NA","NA","NA",null,{"v":0.081086,"d":"0.08"},0,"inf","inf",1,1,"up","no"]
["ENSG00000168334","XIRP1","ENST00000340369","GO:0003723(RNA binding);GO:0003779(actin binding);GO:0030036(actin cytoskeleton organization);GO:0005515(protein binding);GO:0030054(cell junction);GO:0005925(focal adhesion);GO:0007507(heart development);GO:0001725(stress fiber);GO:0031941(filamentous actin);GO:0032091(negative regulation of protein binding)","NA","NA","NA","xin actin binding repeat containing 1 [Source:HGNC Symbol;Acc:HGNC:14301]",0,0,1,0,1,1,"no","no"]
["ENSG00000182013","PNMA8A","ENST00000313683","NA","NA","NA","NA","paraneoplastic Ma antigen family member 8A [Source:HGNC Symbol;Acc:HGNC:25578]",{"v":0.129350553030303,"d":"0.13"},{"v":0.0826162329545455,"d":"0.08"},{"v":1.56567962983098,"d":"1.57"},{"v":0.646789037827994,"d":"0.65"},1,1,"up","no"]
["ENSG00000253785","AC008429.2","ENST00000523057","NA","NA","NA","NA",null,0,{"v":0.051784,"d":"0.05"},"-inf","-inf",1,1,"down","no"]
["ENSG00000159212","CLIC6","ENST00000360731","GO:0006810(transport);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005244(voltage-gated ion channel activity);GO:0006811(ion transport);GO:0034765(regulation of ion transmembrane transport);GO:0005886(plasma membrane);GO:0005254(chloride channel activity);GO:0006821(chloride transport);GO:0034707(chloride channel complex);GO:0005634(nucleus);GO:0070062(extracellular exosome);GO:1902476(chloride transmembrane transport)","NA","NA","NA","chloride intracellular channel 6 [Source:HGNC Symbol;Acc:HGNC:2065]",{"v":0.054864,"d":"0.05"},{"v":0.013184,"d":"0.01"},{"v":4.16140776699029,"d":"4.16"},{"v":2.05707166175242,"d":"2.06"},1,1,"up","no"]
["ENSG00000204524","ZNF805","ENST00000354309;ENST00000414468","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0005622(intracellular);GO:0005622(intracellular)","NA","NA","NA","zinc finger protein 805 [Source:HGNC Symbol;Acc:HGNC:23272]",{"v":0.109105479191439,"d":"0.11"},{"v":0.0446507253269917,"d":"0.04"},{"v":2.44353206789866,"d":"2.44"},{"v":1.28896803803856,"d":"1.29"},1,1,"up","no"]
["ENSG00000254461","AP001107.4","ENST00000533576","NA","NA","NA","NA",null,{"v":0.122596,"d":"0.12"},0,"inf","inf",1,1,"up","no"]
["ENSG00000178919","FOXE1","ENST00000375123","GO:0005634(nucleus);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0043565(sequence-specific DNA binding);GO:0045893(positive regulation of transcription, DNA-templated);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0009653(anatomical structure morphogenesis);GO:0030154(cell differentiation);GO:0045892(negative regulation of transcription, DNA-templated);GO:0000981(RNA polymerase II transcription factor activity, sequence-specific DNA binding);GO:0006590(thyroid hormone generation);GO:0016477(cell migration);GO:0030878(thyroid gland development);GO:0031069(hair follicle morphogenesis);GO:0048538(thymus development);GO:0048562(embryonic organ morphogenesis);GO:0060021(palate development);GO:0060022(hard palate development);GO:0060023(soft palate development);GO:0060465(pharynx development);GO:1904888(cranial skeletal system development)","NA","NA","NA","forkhead box E1 [Source:HGNC Symbol;Acc:HGNC:3806]",0,{"v":0.014505,"d":"0.01"},"-inf","-inf",1,1,"down","no"]
["ENSG00000246145","RRS1-AS1","ENST00000499642","NA","NA","NA","NA","RRS1 antisense RNA 1 (head to head) [Source:HGNC Symbol;Acc:HGNC:50465]",0,{"v":0.009958,"d":"0.01"},"-inf","-inf",1,1,"down","no"]
["ENSG00000182938","OTOP3","ENST00000580749","GO:0003676(nucleic acid binding);GO:0016020(membrane);GO:0016021(integral component of membrane)","NA","NA","NA","otopetrin 3 [Source:HGNC Symbol;Acc:HGNC:19658]",0,0,1,0,1,1,"no","no"]
["ENSG00000116544","DLGAP3","ENST00000373347","GO:0016020(membrane);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0030054(cell junction);GO:0045202(synapse);GO:0045211(postsynaptic membrane);GO:0023052(signaling);GO:0014069(postsynaptic density);GO:0019904(protein domain specific binding);GO:0006461(protein complex assembly);GO:0001540(amyloid-beta binding)","NA","NA","NA","DLG associated protein 3 [Source:HGNC Symbol;Acc:HGNC:30368]",{"v":0.0948244405330651,"d":"0.09"},{"v":0.0307200160925321,"d":"0.03"},{"v":3.08673147329882,"d":"3.09"},{"v":1.62607998279416,"d":"1.63"},1,1,"up","no"]
["ENSG00000180481","GLIPR1L2","ENST00000320460;ENST00000550916","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016021(integral component of membrane)","NA","NA","NA","GLI pathogenesis related 1 like 2 [Source:HGNC Symbol;Acc:HGNC:28592]",{"v":0.0700788414248021,"d":"0.07"},{"v":0.119294490765172,"d":"0.12"},{"v":0.587444072021318,"d":"0.59"},{"v":-0.767476589351511,"d":"-0.77"},1,1,"down","no"]
["ENSG00000135222","CSN2","ENST00000353151","GO:0006810(transport);GO:0005215(transporter activity);GO:0005576(extracellular region);GO:0005515(protein binding);GO:0005615(extracellular space);GO:0005509(calcium ion binding);GO:0004857(enzyme inhibitor activity);GO:0006816(calcium ion transport);GO:0004869(cysteine-type endopeptidase inhibitor activity);GO:0007595(lactation);GO:2000117(negative regulation of cysteine-type endopeptidase activity);GO:1903488(negative regulation of lactation)","04917(Prolactin signaling pathway)","K17107","NA","casein beta [Source:HGNC Symbol;Acc:HGNC:2447]",0,0,1,0,1,1,"no","no"]
["ENSG00000104499","GML","ENST00000220940","GO:0005622(intracellular);GO:0016020(membrane);GO:0005886(plasma membrane);GO:0031225(anchored component of membrane);GO:0006915(apoptotic process);GO:0019898(extrinsic component of membrane);GO:0008285(negative regulation of cell proliferation);GO:0006977(DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest)","NA","NA","NA","glycosylphosphatidylinositol anchored molecule like [Source:HGNC Symbol;Acc:HGNC:4375]",0,0,1,0,1,1,"no","no"]
["ENSG00000237424","FOXD2-AS1","ENST00000445551","NA","NA","NA","NA","FOXD2 antisense RNA 1 (head to head) [Source:HGNC Symbol;Acc:HGNC:44256]",{"v":0.771365,"d":"0.77"},{"v":0.283837,"d":"0.28"},{"v":2.71763371230671,"d":"2.72"},{"v":1.44235102010486,"d":"1.44"},1,1,"up","no"]
["ENSG00000204866","IGFL2","ENST00000593592;ENST00000434646;ENST00000377693","GO:0005576(extracellular region);GO:0005576(extracellular region)","NA","NA","NA","IGF like family member 2 [Source:HGNC Symbol;Acc:HGNC:32929]",0,0,1,0,1,1,"no","no"]
["ENSG00000092345","DAZL","ENST00000250863;ENST00000399444;ENST00000454457","GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0007275(multicellular organism development);GO:0030154(cell differentiation);GO:0007283(spermatogenesis);GO:0045948(positive regulation of translational initiation);GO:0005515(protein binding);GO:0008494(translation activator activity);GO:0007281(germ cell development);GO:0006417(regulation of translation);GO:0003730(mRNA 3'-UTR binding);GO:0070935(3'-UTR-mediated mRNA stabilization);GO:0042802(identical protein binding);GO:0001556(oocyte maturation);GO:0007147(female meiosis II);GO:0045836(positive regulation of meiotic nuclear division);GO:0005844(polysome);GO:0045727(positive regulation of translation);GO:0045727(positive regulation of translation)","NA","NA","NA","deleted in azoospermia like [Source:HGNC Symbol;Acc:HGNC:2685]",{"v":0.0292593247039383,"d":"0.03"},{"v":0.028031744423024,"d":"0.03"},{"v":1.04379250404074,"d":"1.04"},{"v":0.0618349464444351,"d":"0.06"},1,1,"up","no"]
["ENSG00000242736","TRBV1","ENST00000476502","NA","NA","NA","NA","T-cell receptor beta variable 1 (pseudogene) [Source:HGNC Symbol;Acc:HGNC:12176]",{"v":0.369748,"d":"0.37"},0,"inf","inf",1,1,"up","no"]
["MSTRG.15152","AL590627.1","ENST00000626603;ENST00000629344","NA","NA","NA","NA",null,{"v":0.0503310875663381,"d":"0.05"},{"v":0.0135934226686884,"d":"0.01"},{"v":3.70260594355479,"d":"3.70"},{"v":1.88854101628506,"d":"1.89"},1,1,"up","no"]
["ENSG00000213432","RPL17P34","ENST00000394133","NA","NA","NA","NA","ribosomal protein L17 pseudogene 34 [Source:HGNC Symbol;Acc:HGNC:36756]",0,{"v":0.045241,"d":"0.05"},"-inf","-inf",1,1,"down","no"]
["ENSG00000263503","MAPK8IP1P2","ENST00000580257","NA","NA","NA","NA","mitogen-activated protein kinase 8 interacting protein 1 pseudogene 2 [Source:HGNC Symbol;Acc:HGNC:52402]",0,0,1,0,1,1,"no","no"]
["MSTRG.12239","AC008906.1","ENST00000512856","NA","NA","NA","NA",null,{"v":1.07157397702298,"d":"1.07"},{"v":0.163897576423576,"d":"0.16"},{"v":6.53807091237036,"d":"6.54"},{"v":2.70886502476046,"d":"2.71"},1,1,"up","no"]
["ENSG00000259932","AC051619.7","ENST00000568314","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["MSTRG.3919","LINC02340","ENST00000620494","NA","NA","NA","NA","long intergenic non-protein coding RNA 2340 [Source:HGNC Symbol;Acc:HGNC:53260]",{"v":0.445553423497268,"d":"0.45"},{"v":0.0340715819672131,"d":"0.03"},{"v":13.0769808084057,"d":"13.08"},{"v":3.70895758713554,"d":"3.71"},1,1,"up","no"]
["ENSG00000229855","AC008568.1","ENST00000597452;ENST00000433406","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000231991","ANXA2P2","ENST00000435128","NA","NA","NA","NA","annexin A2 pseudogene 2 [Source:HGNC Symbol;Acc:HGNC:539]",0,0,1,0,1,1,"no","no"]
["ENSG00000227418","PCGEM1","ENST00000454040","NA","NA","NA","NA","PCGEM1, prostate-specific transcript (non-protein coding) [Source:HGNC Symbol;Acc:HGNC:30145]",0,0,1,0,1,1,"no","no"]
["ENSG00000263812","LINC00908","ENST00000582452;ENST00000583578;ENST00000578613","NA","NA","NA","NA","long intergenic non-protein coding RNA 908 [Source:HGNC Symbol;Acc:HGNC:27599]",{"v":0.0420035731225296,"d":"0.04"},{"v":0.0335258754940711,"d":"0.03"},{"v":1.25287028313273,"d":"1.25"},{"v":0.325237051875472,"d":"0.33"},1,1,"up","no"]
["ENSG00000228797","FAM207BP","ENST00000447172","NA","NA","NA","NA","family with sequence similarity 207 member B, pseudogene [Source:HGNC Symbol;Acc:HGNC:39715]",{"v":0.025949,"d":"0.03"},0,"inf","inf",1,1,"up","no"]
["ENSG00000173557","C2orf70","ENST00000409392;ENST00000453368;ENST00000479453","GO:0005634(nucleus);GO:0005634(nucleus)","NA","NA","NA","chromosome 2 open reading frame 70 [Source:HGNC Symbol;Acc:HGNC:27938]",0,0,1,0,1,1,"no","no"]
["ENSG00000112769","LAMA4","ENST00000368638;ENST00000230538;ENST00000431543","GO:0007155(cell adhesion);GO:0005102(receptor binding);GO:0030334(regulation of cell migration);GO:0030155(regulation of cell adhesion);GO:0045995(regulation of embryonic development);GO:0001568(blood vessel development);GO:0050873(brown fat cell differentiation);GO:0005604(basement membrane);GO:0005605(basal lamina);GO:0005615(extracellular space);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0005578(proteinaceous extracellular matrix);GO:0070062(extracellular exosome);GO:0031012(extracellular matrix);GO:0030198(extracellular matrix organization);GO:0005201(extracellular matrix structural constituent);GO:0005201(extracellular matrix structural constituent)","04151(PI3K-Akt signaling pathway);04512(ECM-receptor interaction);04510(Focal adhesion);05200(Pathways in cancer);05222(Small cell lung cancer);05165(Human papillomavirus infection);05146(Amoebiasis);05145(Toxoplasmosis);05143(African trypanosomiasis);05143(African trypanosomiasis)","K06241","NA","laminin subunit alpha 4 [Source:HGNC Symbol;Acc:HGNC:6484]",0,0,1,0,1,1,"no","no"]
["ENSG00000254027","AC009902.2","ENST00000518880","NA","NA","NA","NA",null,{"v":0.0424509843081312,"d":"0.04"},{"v":0.0309973466476462,"d":"0.03"},{"v":1.36950380917054,"d":"1.37"},{"v":0.45365327879525,"d":"0.45"},1,1,"up","no"]
["ENSG00000128322","IGLL1","ENST00000330377","GO:0016020(membrane);GO:0005576(extracellular region);GO:0006955(immune response);GO:0050900(leukocyte migration);GO:0003823(antigen binding);GO:0034987(immunoglobulin receptor binding);GO:0006910(phagocytosis, recognition);GO:0006911(phagocytosis, engulfment);GO:0006958(complement activation, classical pathway);GO:0042742(defense response to bacterium);GO:0045087(innate immune response);GO:0050853(B cell receptor signaling pathway);GO:0050871(positive regulation of B cell activation);GO:0009897(external side of plasma membrane);GO:0042571(immunoglobulin complex, circulating);GO:0072562(blood microparticle);GO:0070062(extracellular exosome)","05340(Primary immunodeficiency)","K06554","NA","immunoglobulin lambda like polypeptide 1 [Source:HGNC Symbol;Acc:HGNC:5870]",0,0,1,0,1,1,"no","no"]
["ENSG00000257322","AC138123.2","ENST00000550324;ENST00000552451;ENST00000547432","NA","NA","NA","NA",null,{"v":0.0252403463949843,"d":"0.03"},0,"inf","inf",1,1,"up","no"]
["ENSG00000105290","APLP1","ENST00000537454;ENST00000221891","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0008201(heparin binding);GO:0046914(transition metal ion binding);GO:0048471(perinuclear region of cytoplasm);GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0007155(cell adhesion);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0006915(apoptotic process);GO:0042802(identical protein binding);GO:0006897(endocytosis);GO:0007399(nervous system development);GO:0009887(animal organ morphogenesis);GO:0005604(basement membrane);GO:0031694(alpha-2A adrenergic receptor binding);GO:0031696(alpha-2C adrenergic receptor binding);GO:0030818(negative regulation of cAMP biosynthetic process);GO:0031695(alpha-2B adrenergic receptor binding);GO:0007193(adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway);GO:0071874(cellular response to norepinephrine stimulus);GO:0071874(cellular response to norepinephrine stimulus)","NA","NA","NA","amyloid beta precursor like protein 1 [Source:HGNC Symbol;Acc:HGNC:597]",0,{"v":0.0135512076039387,"d":"0.01"},"-inf","-inf",1,1,"down","no"]
["ENSG00000275185","AC130324.3","ENST00000614165","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000124092","CTCFL","ENST00000608263;ENST00000608903;ENST00000607923","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0006366(transcription from RNA polymerase II promoter);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0016569(covalent chromatin modification);GO:0003677(DNA binding);GO:0007049(cell cycle);GO:0045893(positive regulation of transcription, DNA-templated);GO:0005515(protein binding);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:0010628(positive regulation of gene expression);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0043565(sequence-specific DNA binding);GO:0042393(histone binding);GO:0044212(transcription regulatory region DNA binding);GO:0001077(transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0043046(DNA methylation involved in gamete generation);GO:0016571(histone methylation);GO:0006349(regulation of gene expression by genetic imprinting);GO:0051569(regulation of histone H3-K4 methylation);GO:0051569(regulation of histone H3-K4 methylation)","NA","NA","NA","CCCTC-binding factor like [Source:HGNC Symbol;Acc:HGNC:16234]",0,0,1,0,1,1,"no","no"]
["ENSG00000267082","AC011472.1","ENST00000588634","NA","NA","NA","NA",null,{"v":0.597741,"d":"0.60"},{"v":0.788708,"d":"0.79"},{"v":0.757873636377468,"d":"0.76"},{"v":-0.399970773362923,"d":"-0.40"},1,1,"down","no"]
["ENSG00000162377","COA7","ENST00000371538","GO:0005634(nucleus);GO:0005739(mitochondrion);GO:0005758(mitochondrial intermembrane space)","NA","NA","NA","cytochrome c oxidase assembly factor 7 (putative) [Source:HGNC Symbol;Acc:HGNC:25716]",{"v":0.0925919459783914,"d":"0.09"},{"v":0.781687534213685,"d":"0.78"},{"v":0.118451352907312,"d":"0.12"},{"v":-3.07763341828877,"d":"-3.08"},1,1,"down","no"]
["ENSG00000198944","SOWAHA","ENST00000378693","NA","NA","NA","NA","sosondowah ankyrin repeat domain family member A [Source:HGNC Symbol;Acc:HGNC:27033]",0,0,1,0,1,1,"no","no"]
["ENSG00000174233","ADCY6","ENST00000547260;ENST00000307885","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0035556(intracellular signal transduction);GO:0016829(lyase activity);GO:0005886(plasma membrane);GO:0042995(cell projection);GO:0004016(adenylate cyclase activity);GO:0016849(phosphorus-oxygen lyase activity);GO:0006171(cAMP biosynthetic process);GO:0009190(cyclic nucleotide biosynthetic process);GO:0005515(protein binding);GO:0005929(cilium);GO:0007193(adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway);GO:0031226(intrinsic component of plasma membrane);GO:0019901(protein kinase binding);GO:0010977(negative regulation of neuron projection development);GO:0004383(guanylate cyclase activity);GO:0003091(renal water homeostasis);GO:0006182(cGMP biosynthetic process);GO:0007189(adenylate cyclase-activating G-protein coupled receptor signaling pathway);GO:0007190(activation of adenylate cyclase activity);GO:0007212(dopamine receptor signaling pathway);GO:0034199(activation of protein kinase A activity);GO:0035811(negative regulation of urine volume);GO:0071377(cellular response to glucagon stimulus);GO:0071380(cellular response to prostaglandin E stimulus);GO:0071870(cellular response to catecholamine stimulus);GO:0097746(regulation of blood vessel diameter);GO:1904117(cellular response to vasopressin);GO:1904322(cellular response to forskolin);GO:0008074(guanylate cyclase complex, soluble);GO:0008074(guanylate cyclase complex, soluble)","00230(Purine metabolism);04015(Rap1 signaling pathway);04371(Apelin signaling pathway);04072(Phospholipase D signaling pathway);04024(cAMP signaling pathway);04022(cGMP - PKG signaling pathway);04114(Oocyte meiosis);04540(Gap junction);04611(Platelet activation);04062(Chemokine signaling pathway);04911(Insulin secretion);04923(Regulation of lipolysis in adipocyte);04912(GnRH signaling pathway);04913(Ovarian Steroidogenesis);04915(Estrogen signaling pathway);04914(Progesterone-mediated oocyte maturation);04921(Oxytocin signaling pathway);04926(Relaxin signaling pathway);04918(Thyroid hormone synthesis);04916(Melanogenesis);04924(Renin secretion);04925(Aldosterone synthesis and secretion);04927(Cortisol synthesis and secretion);04261(Adrenergic signaling in cardiomyocytes);04270(Vascular smooth muscle contraction);04970(Salivary secretion);04971(Gastric acid secretion);04972(Pancreatic secretion);04976(Bile secretion);04962(Vasopressin-regulated water reabsorption);04961(Endocrine and other factor-regulated calcium reabsorption);04724(Glutamatergic synapse);04727(GABAergic synapse);04725(Cholinergic synapse);04723(Retrograde endocannabinoid signaling);04742(Taste transduction);04750(Inflammatory mediator regulation of TRP channels);04211(Longevity regulating pathway - mammal);04213(Longevity regulating pathway - multiple species);04713(Circadian entrainment);05200(Pathways in cancer);05032(Morphine addiction);05414(Dilated cardiomyopathy (DCM));05166(HTLV-I infection);01522(Endocrine resistance);01522(Endocrine resistance)","K08046","EC:4.6.1.1","adenylate cyclase 6 [Source:HGNC Symbol;Acc:HGNC:237]",{"v":0.122685713436385,"d":"0.12"},{"v":0.0302562853745541,"d":"0.03"},{"v":4.05488353634994,"d":"4.05"},{"v":2.01966047820499,"d":"2.02"},1,1,"up","no"]
["ENSG00000181392","SYNE4","ENST00000324444;ENST00000465425","GO:0005634(nucleus);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005515(protein binding);GO:0045198(establishment of epithelial cell apical/basal polarity);GO:0005640(nuclear outer membrane);GO:0031309(integral component of nuclear outer membrane);GO:0031309(integral component of nuclear outer membrane)","NA","NA","NA","spectrin repeat containing nuclear envelope family member 4 [Source:HGNC Symbol;Acc:HGNC:26703]",{"v":0.0420252053006329,"d":"0.04"},{"v":0.181047840189873,"d":"0.18"},{"v":0.23212210240431,"d":"0.23"},{"v":-2.1070441938727,"d":"-2.11"},1,1,"down","no"]
["ENSG00000196834","POTEI","ENST00000451531","GO:0005615(extracellular space);GO:0003674(molecular_function);GO:0070062(extracellular exosome);GO:0001895(retina homeostasis)","NA","NA","NA","POTE ankyrin domain family member I [Source:HGNC Symbol;Acc:HGNC:37093]",0,0,1,0,1,1,"no","no"]
["MSTRG.8714","AC012358.2","ENST00000430010","NA","NA","NA","NA",null,{"v":0.11272,"d":"0.11"},{"v":0.177287,"d":"0.18"},{"v":0.635805219784869,"d":"0.64"},{"v":-0.653343234235895,"d":"-0.65"},1,1,"down","no"]
["ENSG00000018607","ZNF806","ENST00000438300","NA","NA","NA","NA","zinc finger protein 806 [Source:HGNC Symbol;Acc:HGNC:33228]",0,0,1,0,1,1,"no","no"]
["ENSG00000187486","KCNJ11","ENST00000339994","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005244(voltage-gated ion channel activity);GO:0006811(ion transport);GO:0006813(potassium ion transport);GO:0034765(regulation of ion transmembrane transport);GO:0005242(inward rectifier potassium channel activity);GO:0015272(ATP-activated inward rectifier potassium channel activity);GO:0005886(plasma membrane);GO:0055085(transmembrane transport);GO:0005887(integral component of plasma membrane);GO:0005524(ATP binding);GO:0008022(protein C-terminus binding);GO:0030506(ankyrin binding);GO:0031072(heat shock protein binding);GO:0002931(response to ischemia);GO:0010107(potassium ion import);GO:0032355(response to estradiol);GO:0033574(response to testosterone);GO:0042493(response to drug);GO:0071316(cellular response to nicotine);GO:0071333(cellular response to glucose stimulus);GO:0071356(cellular response to tumor necrosis factor);GO:1905965(positive regulation of protein targeting to plasma membrane);GO:2001259(positive regulation of cation channel activity);GO:0001669(acrosomal vesicle);GO:0005635(nuclear envelope);GO:0005739(mitochondrion);GO:0005768(endosome);GO:0005783(endoplasmic reticulum);GO:0005829(cytosol);GO:0008282(ATP-sensitive potassium channel complex);GO:0014704(intercalated disc);GO:0030315(T-tubule);GO:0030673(axolemma);GO:0042383(sarcolemma);GO:0043025(neuronal cell body);GO:0043209(myelin sheath);GO:0043231(intracellular membrane-bounded organelle);GO:0070852(cell body fiber);GO:0044325(ion channel binding);GO:1903779(regulation of cardiac conduction);GO:0046676(negative regulation of insulin secretion);GO:0042391(regulation of membrane potential);GO:0050796(regulation of insulin secretion);GO:0008076(voltage-gated potassium channel complex);GO:0050877(neurological system process);GO:0030955(potassium ion binding);GO:0006006(glucose metabolic process);GO:0005249(voltage-gated potassium channel activity);GO:0071805(potassium ion transmembrane transport);GO:0033198(response to ATP)","04911(Insulin secretion);04930(Type II diabetes mellitus)","K05004","NA","potassium voltage-gated channel subfamily J member 11 [Source:HGNC Symbol;Acc:HGNC:6257]",{"v":0.0331582799625468,"d":"0.03"},0,"inf","inf",1,1,"up","no"]
["ENSG00000169242","EFNA1","ENST00000497282;ENST00000368407","GO:0005622(intracellular);GO:0010719(negative regulation of epithelial to mesenchymal transition);GO:0016020(membrane);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0031225(anchored component of membrane);GO:0046875(ephrin receptor binding);GO:0048013(ephrin receptor signaling pathway);GO:0070062(extracellular exosome);GO:0005887(integral component of plasma membrane);GO:0007411(axon guidance);GO:0007267(cell-cell signaling);GO:0005102(receptor binding);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0016477(cell migration);GO:0001525(angiogenesis);GO:0033628(regulation of cell adhesion mediated by integrin);GO:0050731(positive regulation of peptidyl-tyrosine phosphorylation);GO:0003183(mitral valve morphogenesis);GO:0050730(regulation of peptidyl-tyrosine phosphorylation);GO:0034446(substrate adhesion-dependent cell spreading);GO:0061098(positive regulation of protein tyrosine kinase activity);GO:0001934(positive regulation of protein phosphorylation);GO:1902961(positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process);GO:0003180(aortic valve morphogenesis);GO:0000165(MAPK cascade);GO:0000187(activation of MAPK activity);GO:0003199(endocardial cushion to mesenchymal transition involved in heart valve formation);GO:0014028(notochord formation);GO:0030182(neuron differentiation);GO:0043535(regulation of blood vessel endothelial cell migration);GO:0045765(regulation of angiogenesis);GO:0050770(regulation of axonogenesis);GO:0050821(protein stabilization);GO:0061002(negative regulation of dendritic spine morphogenesis);GO:0070244(negative regulation of thymocyte apoptotic process);GO:1902004(positive regulation of amyloid-beta formation);GO:1903051(negative regulation of proteolysis involved in cellular protein catabolic process);GO:0046658(anchored component of plasma membrane);GO:0046658(anchored component of plasma membrane)","04014(Ras signaling pathway);04015(Rap1 signaling pathway);04010(MAPK signaling pathway);04151(PI3K-Akt signaling pathway);04360(Axon guidance);04360(Axon guidance)","K05462","NA","ephrin A1 [Source:HGNC Symbol;Acc:HGNC:3221]",{"v":0.273403018511225,"d":"0.27"},{"v":0.469464867270579,"d":"0.47"},{"v":0.58237162687117,"d":"0.58"},{"v":-0.779988025699289,"d":"-0.78"},1,1,"down","no"]
["MSTRG.2721","KLHL35","ENST00000460787;ENST00000527491;ENST00000376292;ENST00000539798;ENST00000624466","GO:0016567(protein ubiquitination);GO:0005515(protein binding);GO:0004842(ubiquitin-protein transferase activity);GO:0031463(Cul3-RING ubiquitin ligase complex);GO:0031463(Cul3-RING ubiquitin ligase complex)","NA","NA","NA","kelch like family member 35 [Source:HGNC Symbol;Acc:HGNC:26597]",{"v":0.0672749525887721,"d":"0.07"},{"v":0.120080975401706,"d":"0.12"},{"v":0.560246553325518,"d":"0.56"},{"v":-0.835866226681329,"d":"-0.84"},1,1,"down","no"]
["ENSG00000275418","AC104971.4","ENST00000622763","NA","NA","NA","NA",null,{"v":0.275177,"d":"0.28"},{"v":0.370194,"d":"0.37"},{"v":0.743331874638703,"d":"0.74"},{"v":-0.42792162167904,"d":"-0.43"},1,1,"down","no"]
["ENSG00000274102","OR4M2","ENST00000614722","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0004930(G-protein coupled receptor activity);GO:0007186(G-protein coupled receptor signaling pathway);GO:0005886(plasma membrane);GO:0004871(signal transducer activity);GO:0007165(signal transduction);GO:0004984(olfactory receptor activity);GO:0007608(sensory perception of smell);GO:0050896(response to stimulus);GO:0050911(detection of chemical stimulus involved in sensory perception of smell);GO:0004888(transmembrane signaling receptor activity);GO:0050907(detection of chemical stimulus involved in sensory perception)","04740(Olfactory transduction)","K04257","NA","olfactory receptor family 4 subfamily M member 2 [Source:HGNC Symbol;Acc:HGNC:15373]",0,0,1,0,1,1,"no","no"]
["ENSG00000278959","AC006378.2","ENST00000623178","NA","NA","NA","NA",null,0,{"v":0.041108,"d":"0.04"},"-inf","-inf",1,1,"down","no"]
["ENSG00000163873","GRIK3","ENST00000373091","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005216(ion channel activity);GO:0006811(ion transport);GO:0034220(ion transmembrane transport);GO:0005886(plasma membrane);GO:0035725(sodium ion transmembrane transport);GO:0071805(potassium ion transmembrane transport);GO:0030054(cell junction);GO:0045202(synapse);GO:0045211(postsynaptic membrane);GO:0004872(receptor activity);GO:0030425(dendrite);GO:0004970(ionotropic glutamate receptor activity);GO:0005234(extracellular-glutamate-gated ion channel activity);GO:0035235(ionotropic glutamate receptor signaling pathway);GO:0060079(excitatory postsynaptic potential);GO:0005887(integral component of plasma membrane);GO:0030424(axon);GO:0043204(perikaryon);GO:0007196(adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway);GO:0008066(glutamate receptor activity);GO:0007216(G-protein coupled glutamate receptor signaling pathway);GO:0042391(regulation of membrane potential);GO:0032839(dendrite cytoplasm);GO:0015276(ligand-gated ion channel activity);GO:0015277(kainate selective glutamate receptor activity);GO:0043195(terminal bouton);GO:0007215(glutamate receptor signaling pathway);GO:0001640(adenylate cyclase inhibiting G-protein coupled glutamate receptor activity);GO:0001664(G-protein coupled receptor binding);GO:0051967(negative regulation of synaptic transmission, glutamatergic)","04080(Neuroactive ligand-receptor interaction);04724(Glutamatergic synapse)","K05203","NA","glutamate ionotropic receptor kainate type subunit 3 [Source:HGNC Symbol;Acc:HGNC:4581]",0,0,1,0,1,1,"no","no"]
["ENSG00000250742","LINC02381","ENST00000508564","NA","NA","NA","NA","long intergenic non-protein coding RNA 2381 [Source:HGNC Symbol;Acc:HGNC:53304]",0,0,1,0,1,1,"no","no"]
["ENSG00000103460","TOX3","ENST00000566696","GO:0005634(nucleus);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0042803(protein homodimerization activity);GO:0006915(apoptotic process);GO:0045893(positive regulation of transcription, DNA-templated);GO:0005515(protein binding);GO:0003682(chromatin binding);GO:0042981(regulation of apoptotic process);GO:0043524(negative regulation of neuron apoptotic process);GO:0034056(estrogen response element binding);GO:0051219(phosphoprotein binding)","NA","NA","NA","TOX high mobility group box family member 3 [Source:HGNC Symbol;Acc:HGNC:11972]",0,0,1,0,1,1,"no","no"]
["ENSG00000253806","AC108002.2","ENST00000519782","NA","NA","NA","NA",null,{"v":0.743773,"d":"0.74"},0,"inf","inf",1,1,"up","no"]
["ENSG00000064835","POU1F1","ENST00000350375;ENST00000344265","GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0005634(nucleus);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0043565(sequence-specific DNA binding);GO:0045893(positive regulation of transcription, DNA-templated);GO:0006366(transcription from RNA polymerase II promoter);GO:0000981(RNA polymerase II transcription factor activity, sequence-specific DNA binding);GO:0001102(RNA polymerase II activating transcription factor binding);GO:0008285(negative regulation of cell proliferation);GO:0001085(RNA polymerase II transcription factor binding);GO:0001105(RNA polymerase II transcription coactivator activity);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:0001077(transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0003682(chromatin binding);GO:0003714(transcription corepressor activity);GO:0008134(transcription factor binding);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0001708(cell fate specification);GO:0008284(positive regulation of cell proliferation);GO:0008340(determination of adult lifespan);GO:0021983(pituitary gland development);GO:0021984(adenohypophysis development);GO:0030183(B cell differentiation);GO:0032962(positive regulation of inositol trisphosphate biosynthetic process);GO:0040018(positive regulation of multicellular organism growth);GO:0043567(regulation of insulin-like growth factor receptor signaling pathway);GO:0051169(nuclear transport);GO:0060126(somatotropin secreting cell differentiation);GO:0060133(somatotropin secreting cell development);GO:0005667(transcription factor complex);GO:0005667(transcription factor complex)","NA","NA","NA","POU class 1 homeobox 1 [Source:HGNC Symbol;Acc:HGNC:9210]",{"v":0.0068382638623327,"d":"0.01"},{"v":0.0582810898661568,"d":"0.06"},{"v":0.117332463720854,"d":"0.12"},{"v":-3.09132585927657,"d":"-3.09"},1,1,"down","no"]
["ENSG00000158560","DYNC1I1","ENST00000324972;ENST00000630942;ENST00000447467","GO:0006810(transport);GO:0005737(cytoplasm);GO:0005694(chromosome);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0005874(microtubule);GO:0003774(motor activity);GO:0007018(microtubule-based movement);GO:0005634(nucleus);GO:0005868(cytoplasmic dynein complex);GO:0000922(spindle pole);GO:0000775(chromosome, centromeric region);GO:0000776(kinetochore);GO:0000777(condensed chromosome kinetochore);GO:0030286(dynein complex);GO:0005829(cytosol);GO:0055037(recycling endosome);GO:0007062(sister chromatid cohesion);GO:0019886(antigen processing and presentation of exogenous peptide antigen via MHC class II);GO:0031982(vesicle);GO:0006888(ER to Golgi vesicle-mediated transport);GO:0008574(ATP-dependent microtubule motor activity, plus-end-directed);GO:0003777(microtubule motor activity);GO:0008017(microtubule binding);GO:0030507(spectrin binding);GO:0045503(dynein light chain binding);GO:0045504(dynein heavy chain binding);GO:0047496(vesicle transport along microtubule);GO:2000582(positive regulation of ATP-dependent microtubule motor activity, plus-end-directed);GO:0036464(cytoplasmic ribonucleoprotein granule);GO:0048471(perinuclear region of cytoplasm);GO:0048471(perinuclear region of cytoplasm)","04145(Phagosome);04962(Vasopressin-regulated water reabsorption);05132(Salmonella infection);05132(Salmonella infection)","K10415","NA","dynein cytoplasmic 1 intermediate chain 1 [Source:HGNC Symbol;Acc:HGNC:2963]",{"v":0.0232570818739054,"d":"0.02"},{"v":0.0111406414185639,"d":"0.01"},{"v":2.0875891252681,"d":"2.09"},{"v":1.06183779176036,"d":"1.06"},1,1,"up","no"]
["ENSG00000230062","ANKRD66","ENST00000445060","GO:0005622(intracellular)","NA","NA","NA","ankyrin repeat domain 66 [Source:HGNC Symbol;Acc:HGNC:44669]",0,{"v":0.0137845205850488,"d":"0.01"},"-inf","-inf",1,1,"down","no"]
["ENSG00000163687","DNASE1L3","ENST00000463694;ENST00000486455;ENST00000483681;ENST00000394549","GO:0005634(nucleus);GO:0016787(hydrolase activity);GO:0005783(endoplasmic reticulum);GO:0005576(extracellular region);GO:0006915(apoptotic process);GO:0004519(endonuclease activity);GO:0004518(nuclease activity);GO:0004536(deoxyribonuclease activity);GO:0006308(DNA catabolic process);GO:0003677(DNA binding);GO:0006259(DNA metabolic process);GO:0012501(programmed cell death);GO:0005509(calcium ion binding);GO:0006309(apoptotic DNA fragmentation);GO:0090305(nucleic acid phosphodiester bond hydrolysis);GO:0004520(endodeoxyribonuclease activity);GO:0010623(programmed cell death involved in cell development);GO:0010623(programmed cell death involved in cell development)","NA","NA","NA","deoxyribonuclease 1 like 3 [Source:HGNC Symbol;Acc:HGNC:2959]",{"v":0.14636217407878,"d":"0.15"},{"v":0.371555583227446,"d":"0.37"},{"v":0.393917305204872,"d":"0.39"},{"v":-1.34403529742043,"d":"-1.34"},1,1,"down","no"]
["ENSG00000214491","SEC14L6","ENST00000402034","GO:0016021(integral component of membrane);GO:0006810(transport);GO:0005215(transporter activity);GO:0005622(intracellular)","NA","NA","NA","SEC14 like lipid binding 6 [Source:HGNC Symbol;Acc:HGNC:40047]",{"v":0.005289,"d":"0.01"},{"v":0.04501,"d":"0.05"},{"v":0.117507220617641,"d":"0.12"},{"v":-3.08917868423158,"d":"-3.09"},1,1,"down","no"]
["ENSG00000275411","MIR6882","ENST00000619233","NA","NA","NA","NA","microRNA 6882 [Source:HGNC Symbol;Acc:HGNC:49928]",0,{"v":0.012766,"d":"0.01"},"-inf","-inf",1,1,"down","no"]
["ENSG00000151418","ATP6V1G3","ENST00000367382","GO:0006810(transport);GO:0005829(cytosol);GO:0015992(proton transport);GO:0006811(ion transport);GO:0005886(plasma membrane);GO:1902600(hydrogen ion transmembrane transport);GO:0016820(hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances);GO:0016471(vacuolar proton-transporting V-type ATPase complex);GO:0034220(ion transmembrane transport);GO:0008286(insulin receptor signaling pathway);GO:0033572(transferrin transport);GO:0090383(phagosome acidification);GO:0051117(ATPase binding);GO:0008553(hydrogen-exporting ATPase activity, phosphorylative mechanism)","00190(Oxidative phosphorylation);04150(mTOR signaling pathway);04145(Phagosome);04966(Collecting duct acid secretion);04721(Synaptic vesicle cycle);05323(Rheumatoid arthritis);05110(Vibrio cholerae infection);05120(Epithelial cell signaling in Helicobacter pylori infection)","K02152","NA","ATPase H+ transporting V1 subunit G3 [Source:HGNC Symbol;Acc:HGNC:18265]",0,0,1,0,1,1,"no","no"]
["MSTRG.234","ELOA-AS1","ENST00000427796;ENST00000447961","NA","NA","NA","NA","ELOA antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:50582]",{"v":0.230524376391982,"d":"0.23"},{"v":0.276443919821826,"d":"0.28"},{"v":0.833892011589764,"d":"0.83"},{"v":-0.262067527082066,"d":"-0.26"},1,1,"down","no"]
["ENSG00000161652","IZUMO2","ENST00000600293;ENST00000594854","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005634(nucleus);GO:0005634(nucleus)","NA","NA","NA","IZUMO family member 2 [Source:HGNC Symbol;Acc:HGNC:28518]",0,0,1,0,1,1,"no","no"]
["ENSG00000284677","AL031985.4","ENST00000642138","NA","NA","NA","NA",null,{"v":0.049908,"d":"0.05"},{"v":0.120731,"d":"0.12"},{"v":0.413381815772254,"d":"0.41"},{"v":-1.2744531673533,"d":"-1.27"},1,1,"down","no"]
["ENSG00000222047","C10orf55","ENST00000409178","NA","NA","NA","NA","chromosome 10 open reading frame 55 [Source:HGNC Symbol;Acc:HGNC:31008]",0,0,1,0,1,1,"no","no"]
["ENSG00000283294","AP005212.5","ENST00000577614","NA","NA","NA","NA",null,{"v":0.040219,"d":"0.04"},{"v":0.111563,"d":"0.11"},{"v":0.360504826869123,"d":"0.36"},{"v":-1.47190951876793,"d":"-1.47"},1,1,"down","no"]
["ENSG00000215102","TERF1P4","ENST00000399580","NA","NA","NA","NA","telomeric repeat binding factor 1 pseudogene 4 [Source:HGNC Symbol;Acc:HGNC:38500]",0,{"v":0.011108,"d":"0.01"},"-inf","-inf",1,1,"down","no"]
["ENSG00000233467","U40455.1","ENST00000411473","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["MSTRG.6300","AC005696.2","ENST00000610120","NA","NA","NA","NA",null,{"v":0.665995,"d":"0.67"},0,"inf","inf",1,1,"up","no"]
["MSTRG.1234","RN7SL230P","ENST00000580835","NA","NA","NA","NA","RNA, 7SL, cytoplasmic 230, pseudogene [Source:HGNC Symbol;Acc:HGNC:46246]",0,{"v":0.16796,"d":"0.17"},"-inf","-inf",1,1,"down","no"]
["ENSG00000167494","NOS2P2","ENST00000639528","NA","NA","NA","NA","nitric oxide synthase 2 pseudogene 2 [Source:HGNC Symbol;Acc:HGNC:7874]",0,0,1,0,1,1,"no","no"]
["ENSG00000146250","PRSS35","ENST00000369700","GO:0005576(extracellular region);GO:0005739(mitochondrion)","NA","NA","NA","protease, serine 35 [Source:HGNC Symbol;Acc:HGNC:21387]",{"v":0.130046,"d":"0.13"},{"v":0.146001,"d":"0.15"},{"v":0.890719926575845,"d":"0.89"},{"v":-0.166956225495745,"d":"-0.17"},1,1,"down","no"]
["ENSG00000271538","LINC02427","ENST00000605270","NA","NA","NA","NA","long intergenic non-protein coding RNA 2427 [Source:HGNC Symbol;Acc:HGNC:53358]",{"v":0.0009837196485623,"d":"0.00"},{"v":0.106059865015974,"d":"0.11"},{"v":0.00927513577746058,"d":"0.01"},{"v":-6.75241588335611,"d":"-6.75"},1,1,"down","no"]
["ENSG00000112562","SMOC2","ENST00000354536","GO:0046872(metal ion binding);GO:0005509(calcium ion binding);GO:0007165(signal transduction);GO:0005576(extracellular region);GO:0005578(proteinaceous extracellular matrix);GO:0005604(basement membrane);GO:0005539(glycosaminoglycan binding);GO:0008201(heparin binding);GO:0010811(positive regulation of cell-substrate adhesion);GO:0030198(extracellular matrix organization);GO:0005614(interstitial matrix);GO:0016020(membrane);GO:0016021(integral component of membrane)","NA","NA","NA","SPARC related modular calcium binding 2 [Source:HGNC Symbol;Acc:HGNC:20323]",0,{"v":0.01166875,"d":"0.01"},"-inf","-inf",1,1,"down","no"]
["MSTRG.12842","LINC01149","ENST00000430364","NA","NA","NA","NA","long intergenic non-protein coding RNA 1149 [Source:HGNC Symbol;Acc:HGNC:39757]",0,0,1,0,1,1,"no","no"]
["ENSG00000228157","AC007952.2","ENST00000574724;ENST00000399091","NA","NA","NA","NA",null,{"v":0.189468728123991,"d":"0.19"},{"v":0.065730292864062,"d":"0.07"},{"v":2.88251763179931,"d":"2.88"},{"v":1.5273294325888,"d":"1.53"},1,1,"up","no"]
["ENSG00000229503","AC092155.2","ENST00000454675","NA","NA","NA","NA",null,{"v":0.098605,"d":"0.10"},{"v":0.430257,"d":"0.43"},{"v":0.229176980269932,"d":"0.23"},{"v":-2.12546595532253,"d":"-2.13"},1,1,"down","no"]
["ENSG00000219435","CATSPERZ","ENST00000535981;ENST00000539943","GO:0016020(membrane);GO:0005886(plasma membrane);GO:0042995(cell projection);GO:0030154(cell differentiation);GO:0007283(spermatogenesis);GO:0005737(cytoplasm);GO:0030317(flagellated sperm motility);GO:0048240(sperm capacitation);GO:0097228(sperm principal piece);GO:0036128(CatSper complex);GO:0007140(male meiotic nuclear division);GO:0007140(male meiotic nuclear division)","NA","NA","NA","catsper channel auxiliary subunit zeta [Source:HGNC Symbol;Acc:HGNC:19231]",0,{"v":0.0223622156133829,"d":"0.02"},"-inf","-inf",1,1,"down","no"]

{"sheet":"Table 2","index":1,"n_rows":131,"n_cols":6,"rows_kept":131}
["gene_name","FPKM.T1","FPKM.T2","qval","regulation","significant"]
["CCR1",0.31,45.87,0,"up","yes"]
["AL732372.2;AL627309.2",0.25,6.31,0,"up","yes"]
["FAM46C",0.28,5.59,0,"up","yes"]
["NEAT1;NEAT1_1",0.23,4.32,0,"up","yes"]
["FPR2",1.69,29.56,0,"up","yes"]
["S1PR1",1.06,18.52,0,"up","yes"]
["CEBPG",0.28,4.92,0,"up","yes"]
["WBP1L",1.27,20.71,0,"up","yes"]
["KIAA0040",2.16,30.78,0,"up","yes"]
["TCEANC2",0.09,1.14,0,"up","yes"]
["HEG1",0.25,2.68,0,"up","yes"]
["GRPEL2",0.29,3.15,0,"up","yes"]
["HBA2",445.37,4541.34,0,"up","yes"]
["RUNX1",0.31,3.21,0,"up","yes"]
["RNASE6",0.78,8.39,0,"up","yes"]
["C1GALT1C1",0.48,5.04,0,"up","yes"]
["PLEKHF1",0.48,4.79,0.01,"up","yes"]
["FFAR2",2.25,21.1,0.01,"up","yes"]
["MAML3",0.37,3.5,0.01,"up","yes"]
["VASH1",0.28,2.67,0.01,"up","yes"]
["HELB",0.23,2.13,0.01,"up","yes"]
["RBM12B",0.19,1.8,0.01,"up","yes"]
["TMEM167A",1.43,12.62,0.01,"up","yes"]
["AC113404.3",1.52,13.21,0.01,"up","yes"]
["TGOLN2",4.51,37.2,0.01,"up","yes"]
["AC090114.3;AC018638.8;AC108010.1",0.53,4.72,0.01,"up","yes"]
["ZNF227",0.21,1.83,0.01,"up","yes"]
["SLC35D1",0.3,2.5,0.01,"up","yes"]
["C5AR1",12.55,99.83,0.02,"up","yes"]
["NECTIN1",0.22,1.8,0.02,"up","yes"]
["RBM43",0.23,1.89,0.02,"up","yes"]
["UBXN7",0.76,5.94,0.02,"up","yes"]
["XIAP",0.53,4.17,0.02,"up","yes"]
["BCORL1",0.26,2.05,0.02,"up","yes"]
["IER3",0.94,7.48,0.02,"up","yes"]
["SPEN",1.45,10.38,0.03,"up","yes"]
["ZNF672",0.59,4.27,0.03,"up","yes"]
["ERC1",0.17,1.24,0.03,"up","yes"]
["C7orf73",1.08,7.68,0.03,"up","yes"]
["AHNAK",10.58,74.24,0.03,"up","yes"]
["GDF11",0.17,1.24,0.03,"up","yes"]
["RREB1",0.21,1.51,0.03,"up","yes"]
["KDM6B",3.25,22.35,0.03,"up","yes"]
["PPRC1",0.48,3.39,0.03,"up","yes"]
["PAFAH1B2",0.96,6.61,0.03,"up","yes"]
["NFIC",0.2,1.39,0.03,"up","yes"]
["CBL",2.08,14.09,0.03,"up","yes"]
["XIST",1.91,12.87,0.03,"up","yes"]
["PNN",1.2,8.13,0.03,"up","yes"]
["GPATCH2L",0.39,2.63,0.03,"up","yes"]
["NOTCH2",3.32,21.87,0.04,"up","yes"]
["AAK1",0.49,3.22,0.04,"up","yes"]
["CPEB4",0.56,3.72,0.04,"up","yes"]
["IGF1R",0.9,5.84,0.04,"up","yes"]
["ZNF808",0.3,1.99,0.04,"up","yes"]
["SLC16A7",0.17,1.1,0.04,"up","yes"]
["ARID1A",1.47,9.37,0.04,"up","yes"]
["ZC3H4",0.87,5.6,0.04,"up","yes"]
["KMT2C",1.4,8.91,0.04,"up","yes"]
["RNF144B",1.47,9.11,0.05,"up","yes"]
["EGLN1",3.21,19.75,0.05,"up","yes"]
["CREBBP",2.49,15.32,0.05,"up","yes"]
["PTAFR",38.07,0.25,0,"down","yes"]
["KCNJ2",8.21,0.16,0,"down","yes"]
["CX3CR1",38.57,0.98,0,"down","yes"]
["CARD8-AS1",15.57,0.41,0,"down","yes"]
["CXCR1",150.87,4.63,0,"down","yes"]
["FAM212B",13.7,0.68,0,"down","yes"]
["USP8P1",44.3,2.42,0,"down","yes"]
["FPR1",282.96,17.91,0,"down","yes"]
["RPSAP58",52.24,3.48,0,"down","yes"]
["ENDOD1",5.95,0.4,0,"down","yes"]
["FBXO34",4.88,0.32,0,"down","yes"]
["AL034397.3",21.41,1.59,0,"down","yes"]
["MRPL57",7.6,0.55,0,"down","yes"]
["SERTAD2",3.47,0.26,0,"down","yes"]
["GVINP1",1.19,0.1,0,"down","yes"]
["ZNF627",2.78,0.23,0,"down","yes"]
["MED18",5.83,0.49,0,"down","yes"]
["CKAP4",10.78,1,0,"down","yes"]
["YWHAG",11.06,1.05,0,"down","yes"]
["TMEM140",31.89,3.14,0,"down","yes"]
["TIFA",3.79,0.4,0,"down","yes"]
["VCPIP1",3.69,0.41,0,"down","yes"]
["MFSD5",4.46,0.46,0,"down","yes"]
["ARL4C",18.92,2.17,0,"down","yes"]
["IRF2BP2",5.57,0.63,0,"down","yes"]
["VOPP1",15.55,1.79,0,"down","yes"]
["PPP1R3B",9.66,1.24,0,"down","yes"]
["SIAH1",1.65,0.22,0,"down","yes"]
["ZNF136",1.45,0.2,0,"down","yes"]
["DYRK2",2.82,0.41,0,"down","yes"]
["GSEC",1.95,0.27,0,"down","yes"]
["MRPL34",8.82,1.31,0.01,"down","yes"]
["POLR3K",3.8,0.56,0.01,"down","yes"]
["HPCAL4",1.47,0.22,0.01,"down","yes"]
["HNRNPA1P48",23.12,3.71,0.01,"down","yes"]
["TRIM44",3.05,0.49,0.01,"down","yes"]
["MUL1",6.69,1.09,0.01,"down","yes"]
["LINC002481",3.46,0.54,0.01,"down","yes"]
["CD93",13.39,2.28,0.01,"down","yes"]
["TUBB1",88.92,15.55,0.01,"down","yes"]
["VAMP8",61.99,10.94,0.01,"down","yes"]
["FAM136A",4.76,0.88,0.02,"down","yes"]
["PEX2",5.26,0.98,0.02,"down","yes"]
["GNA12",4.55,0.88,0.02,"down","yes"]
["THAP12",6.29,1.22,0.02,"down","yes"]
["THAP1",4.96,0.95,0.02,"down","yes"]
["IFIT2",11.14,2.2,0.02,"down","yes"]
["RAB39B",1.78,0.33,0.02,"down","yes"]
["HIST1H4H",1.88,0.35,0.02,"down","yes"]
["SPTSSA",4.07,0.79,0.02,"down","yes"]
["SH2D1A;TEX13D",5.25,1.05,0.03,"down","yes"]
["ZNF792",1.45,0.28,0.03,"down","yes"]
["TMEM242",1.22,0.23,0.03,"down","yes"]
["ZNF337",2.4,0.47,0.03,"down","yes"]
["DHFR",1.55,0.31,0.03,"down","yes"]
["BET1L",6.55,1.37,0.03,"down","yes"]
["ALKBH5",9.02,1.92,0.03,"down","yes"]
["MAP1LC3B",14.84,3.24,0.04,"down","yes"]
["SDHAF4",2.62,0.54,0.04,"down","yes"]
["ZNF83",2,0.43,0.04,"down","yes"]
["CCDC167",8.41,1.8,0.04,"down","yes"]
["EEF1A1P6",12.69,2.85,0.04,"down","yes"]
["TUBB",37.98,8.79,0.05,"down","yes"]
["SLC35A4",3.74,0.86,0.05,"down","yes"]
["SMIM5",2.68,0.62,0.05,"down","yes"]
["RPS15",110.05,26.03,0.05,"down","yes"]
["LSM2",11.61,2.68,0.05,"down","yes"]
["GPR18",7.9,1.84,0.05,"down","yes"]

{"sheet":"Table 3","index":2,"n_rows":29035,"n_cols":16,"rows_kept":4500,"cut":true,"bounds":{"rows_first":2000,"rows_last":500,"rows_between":2000,"halvings":0}}
["gene_id","gene_name","transcript_id","GO","KEGG","KO_ENTRY","EC","Description","FPKM.T4","FPKM.T3","fc","log2(fc)","pval","qval","regulation","significant"]
["MSTRG.9928","FP671120.3","ENST00000631211","NA","NA","NA","NA",null,{"v":79.968109,"d":"79.97"},{"v":1.278632,"d":"1.28"},{"v":62.5419268405608,"d":"62.54"},{"v":5.96675176251136,"d":"5.97"},{"v":2.22741665124564E-13,"d":"0.00"},{"v":2.33936382183193e-09,"d":"0.00"},"up","yes"]
["MSTRG.280","CD52","MSTRG.280.1;ENST00000470468;ENST00000374213;ENST00000492808","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005886(plasma membrane);GO:0031225(anchored component of membrane);GO:0005576(extracellular region);GO:0006501(C-terminal protein lipidation);GO:0005887(integral component of plasma membrane);GO:0007204(positive regulation of cytosolic calcium ion concentration);GO:0045730(respiratory burst);GO:0045730(respiratory burst)","NA","NA","NA","CD52 molecule [Source:HGNC Symbol;Acc:HGNC:1804]",{"v":1.1102838754386,"d":"1.11"},{"v":68.3166597692983,"d":"68.32"},{"v":0.0162520222620364,"d":"0.02"},{"v":-5.94323694388662,"d":"-5.94"},{"v":3.89254334864643e-13,"d":"0.00"},{"v":2.33936382183193e-09,"d":"0.00"},"down","yes"]
["MSTRG.10045","KCNJ15;DSCR8","ENST00000419868;ENST00000417042;ENST00000613499;ENST00000328656;ENST00000548700;ENST00000438657;ENST00000465532;ENST00000398934;ENST00000398925;ENST00000549805;ENST00000547595;ENST00000547341;ENST00000398938;MSTRG.10045.17;ENST00000443341;ENST00000398928;MSTRG.10045.16;ENST00000398927;ENST00000398932;ENST00000398930;ENST00000612702","GO:0016020(membrane);GO:0006813(potassium ion transport);GO:0005242(inward rectifier potassium channel activity);GO:0071805(potassium ion transmembrane transport);GO:0016021(integral component of membrane);GO:0006810(transport);GO:0005244(voltage-gated ion channel activity);GO:0006811(ion transport);GO:0034765(regulation of ion transmembrane transport);GO:0005515(protein binding);GO:0005886(plasma membrane);GO:0005887(integral component of plasma membrane);GO:0010107(potassium ion import);GO:0015467(G-protein activated inward rectifier potassium channel activity);GO:0003674(molecular_function);GO:0008150(biological_process);GO:0005575(cellular_component);GO:0015467(G-protein activated inward rectifier potassium channel activity)","04971(Gastric acid secretion);04971(Gastric acid secretion)","K05008","NA","potassium voltage-gated channel subfamily J member 15 [Source:HGNC Symbol;Acc:HGNC:6261];Down syndrome critical region 8 (non-protein coding) [Source:HGNC Symbol;Acc:HGNC:16707]",{"v":0.209713767493752,"d":"0.21"},{"v":12.2999176759193,"d":"12.30"},{"v":0.0170500139122336,"d":"0.02"},{"v":-5.87408327333453,"d":"-5.87"},{"v":5.82801151427985e-13,"d":"0.00"},{"v":2.33936382183193e-09,"d":"0.00"},"down","yes"]
["MSTRG.734","S1PR1","ENST00000305352;ENST00000475821;MSTRG.734.1;ENST00000475289","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0043231(intracellular membrane-bounded organelle);GO:0004930(G-protein coupled receptor activity);GO:0007186(G-protein coupled receptor signaling pathway);GO:0005654(nucleoplasm);GO:0005886(plasma membrane);GO:0004871(signal transducer activity);GO:0007165(signal transduction);GO:0038036(sphingosine-1-phosphate receptor activity);GO:0045121(membrane raft);GO:0006935(chemotaxis);GO:0005768(endosome);GO:0030500(regulation of bone mineralization);GO:0072678(T cell migration);GO:0007155(cell adhesion);GO:0031226(intrinsic component of plasma membrane);GO:0030032(lamellipodium assembly);GO:0001664(G-protein coupled receptor binding);GO:0016477(cell migration);GO:0001525(angiogenesis);GO:0031532(actin cytoskeleton reorganization);GO:0003376(sphingosine-1-phosphate signaling pathway);GO:0045124(regulation of bone resorption);GO:0001955(blood vessel maturation);GO:0046625(sphingolipid binding);GO:0003245(cardiac muscle tissue growth involved in heart morphogenesis);GO:0007193(adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway);GO:0007420(brain development);GO:0008284(positive regulation of cell proliferation);GO:0019226(transmission of nerve impulse);GO:0030155(regulation of cell adhesion);GO:0030182(neuron differentiation);GO:0030335(positive regulation of cell migration);GO:0030595(leukocyte chemotaxis);GO:0043547(positive regulation of GTPase activity);GO:0045446(endothelial cell differentiation);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0048661(positive regulation of smooth muscle cell proliferation);GO:0050927(positive regulation of positive chemotaxis);GO:0051482(positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway);GO:0051497(negative regulation of stress fiber assembly);GO:0061384(heart trabecula morphogenesis);GO:0009897(external side of plasma membrane);GO:0009897(external side of plasma membrane)","04068(FoxO signaling pathway);04071(Sphingolipid signaling pathway);04080(Neuroactive ligand-receptor interaction);04080(Neuroactive ligand-receptor interaction)","K04288","NA","sphingosine-1-phosphate receptor 1 [Source:HGNC Symbol;Acc:HGNC:3165]",{"v":22.8240555285996,"d":"22.82"},{"v":0.429529226107226,"d":"0.43"},{"v":53.1373749242895,"d":"53.14"},{"v":5.73165505291423,"d":"5.73"},{"v":8.34643057122354e-13,"d":"0.00"},{"v":2.51269292346685e-09,"d":"0.00"},"up","yes"]
["MSTRG.9127","CXCR4","ENST00000409817;ENST00000466288;ENST00000241393","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0004930(G-protein coupled receptor activity);GO:0007186(G-protein coupled receptor signaling pathway);GO:0003779(actin binding);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0004871(signal transducer activity);GO:0007165(signal transduction);GO:0004950(chemokine receptor activity);GO:0006935(chemotaxis);GO:0070098(chemokine-mediated signaling pathway);GO:0030054(cell junction);GO:0031410(cytoplasmic vesicle);GO:0005764(lysosome);GO:0019955(cytokine binding);GO:0005768(endosome);GO:0031252(cell leading edge);GO:0070062(extracellular exosome);GO:0005769(early endosome);GO:0001666(response to hypoxia);GO:0016032(viral process);GO:0031625(ubiquitin protein ligase binding);GO:0005770(late endosome);GO:0043130(ubiquitin binding);GO:0005737(cytoplasm);GO:0006954(inflammatory response);GO:0006915(apoptotic process);GO:0009986(cell surface);GO:0043234(protein complex);GO:0015026(coreceptor activity);GO:0002407(dendritic cell chemotaxis);GO:0009615(response to virus);GO:0001618(virus receptor activity);GO:0007204(positive regulation of cytosolic calcium ion concentration);GO:0071345(cellular response to cytokine stimulus);GO:0000187(activation of MAPK activity);GO:0019064(fusion of virus membrane with host plasma membrane);GO:0030260(entry into host cell);GO:0050920(regulation of chemotaxis);GO:0016494(C-X-C chemokine receptor activity);GO:0019957(C-C chemokine binding);GO:0032027(myosin light chain binding);GO:0019722(calcium-mediated signaling);GO:0043217(myelin maintenance);GO:0048714(positive regulation of oligodendrocyte differentiation);GO:0048714(positive regulation of oligodendrocyte differentiation)","04060(Cytokine-cytokine receptor interaction);04144(Endocytosis);04670(Leukocyte transendothelial migration);04672(Intestinal immune network for IgA production);04062(Chemokine signaling pathway);04360(Axon guidance);05200(Pathways in cancer);05200(Pathways in cancer)","K04189","NA","C-X-C motif chemokine receptor 4 [Source:HGNC Symbol;Acc:HGNC:2561]",{"v":1.64142361915468,"d":"1.64"},{"v":80.3342240840827,"d":"80.33"},{"v":0.0204324326010377,"d":"0.02"},{"v":-5.61299521416507,"d":"-5.61"},{"v":2.48798260766423e-12,"d":"0.00"},{"v":5.99205731229853e-09,"d":"0.00"},"down","yes"]
["MSTRG.9941","FP236383.3;FP236383.2","ENST00000627981;ENST00000625598;MSTRG.9941.1","NA","NA","NA","NA",null,{"v":65.2940451961722,"d":"65.29"},{"v":1.57297313290803,"d":"1.57"},{"v":41.5099557838347,"d":"41.51"},{"v":5.37538549007927,"d":"5.38"},{"v":8.43287079843782e-12,"d":"0.00"},{"v":1.69247716924647e-08,"d":"0.00"},"up","yes"]
["MSTRG.14454","PLEKHF2","ENST00000315367;ENST00000519516","GO:0006810(transport);GO:0016020(membrane);GO:0015031(protein transport);GO:0046872(metal ion binding);GO:0005783(endoplasmic reticulum);GO:0005515(protein binding);GO:0005768(endosome);GO:0031901(early endosome membrane);GO:0030133(transport vesicle);GO:0030133(transport vesicle)","NA","NA","NA","pleckstrin homology and FYVE domain containing 2 [Source:HGNC Symbol;Acc:HGNC:20757]",{"v":0.235517387631495,"d":"0.24"},{"v":9.80454283455531,"d":"9.80"},{"v":0.0240212513327427,"d":"0.02"},{"v":-5.37954488283941,"d":"-5.38"},{"v":2.12536355693455E-11,"d":"0.00"},{"v":3.65623256465798e-08,"d":"0.00"},"down","yes"]
["MSTRG.4637","IFI27","MSTRG.4637.8;ENST00000620066;ENST00000614648;ENST00000616764;ENST00000618200;ENST00000621160;ENST00000555081;ENST00000614288;MSTRG.4637.7;ENST00000614204;ENST00000618863;ENST00000557700;ENST00000612499","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016021(integral component of membrane)","NA","NA","NA","interferon alpha inducible protein 27 [Source:HGNC Symbol;Acc:HGNC:5397]",{"v":15.9965422848879,"d":"16.00"},{"v":0.529145674620391,"d":"0.53"},{"v":30.230885467152,"d":"30.23"},{"v":4.91795133122514,"d":"4.92"},{"v":2.08503175810834e-10,"d":"0.00"},{"v":3.13849405389259E-7,"d":"0.00"},"up","yes"]
["MSTRG.11201","MSL2","ENST00000473093;ENST00000309993;ENST00000481989;ENST00000491050","GO:0046872(metal ion binding);GO:0016567(protein ubiquitination);GO:0016874(ligase activity);GO:0061630(ubiquitin protein ligase activity);GO:0005654(nucleoplasm);GO:0043984(histone H4-K16 acetylation);GO:0072487(MSL complex);GO:0072487(MSL complex)","NA","NA","NA","MSL complex subunit 2 [Source:HGNC Symbol;Acc:HGNC:25544]",{"v":7.89344176133464,"d":"7.89"},{"v":0.267182294013739,"d":"0.27"},{"v":29.543281640245,"d":"29.54"},{"v":4.88475818311434,"d":"4.88"},{"v":2.71034460921206e-10,"d":"0.00"},{"v":3.62644108712573e-07,"d":"0.00"},"up","yes"]
["MSTRG.13594","TRGV8","MSTRG.13594.1;ENST00000390343","NA","NA","NA","NA","T-cell receptor gamma variable 8 [Source:HGNC Symbol;Acc:HGNC:12294]",{"v":10.9307345460449,"d":"10.93"},{"v":0.426530337662338,"d":"0.43"},{"v":25.6270974907726,"d":"25.63"},{"v":4.67959818402045,"d":"4.68"},{"v":1.59109943404134e-09,"d":"0.00"},{"v":1.91600193847258E-6,"d":"0.00"},"up","yes"]
["MSTRG.7695","LRG1;PLIN5;AC011498.4","ENST00000306390;ENST00000586883;ENST00000381848;ENST00000586020;ENST00000588887;ENST00000589728;ENST00000592610;ENST00000590350","GO:0016020(membrane);GO:0043231(intracellular membrane-bounded organelle);GO:0005576(extracellular region);GO:0005615(extracellular space);GO:0003674(molecular_function);GO:0008150(biological_process);GO:0070062(extracellular exosome);GO:0043312(neutrophil degranulation);GO:1904813(ficolin-1-rich granule lumen);GO:0035580(specific granule lumen);GO:1904724(tertiary granule lumen);GO:0005160(transforming growth factor beta receptor binding);GO:0001938(positive regulation of endothelial cell proliferation);GO:0030511(positive regulation of transforming growth factor beta receptor signaling pathway);GO:0045766(positive regulation of angiogenesis);GO:0050873(brown fat cell differentiation);GO:0005737(cytoplasm);GO:0005739(mitochondrion);GO:0005811(lipid particle);GO:0010867(positive regulation of triglyceride biosynthetic process);GO:0010884(positive regulation of lipid storage);GO:2000378(negative regulation of reactive oxygen species metabolic process);GO:0034389(lipid particle organization);GO:0010897(negative regulation of triglyceride catabolic process);GO:0035473(lipase binding);GO:0042802(identical protein binding);GO:0010890(positive regulation of sequestering of triglyceride);GO:0019915(lipid storage);GO:0031999(negative regulation of fatty acid beta-oxidation);GO:0032000(positive regulation of fatty acid beta-oxidation);GO:0035359(negative regulation of peroxisome proliferator activated receptor signaling pathway);GO:0050995(negative regulation of lipid catabolic process);GO:0051646(mitochondrion localization);GO:0060192(negative regulation of lipase activity);GO:0060193(positive regulation of lipase activity);GO:0005829(cytosol);GO:0005829(cytosol)","03320(PPAR signaling pathway);03320(PPAR signaling pathway)","K20255","NA","leucine rich alpha-2-glycoprotein 1 [Source:HGNC Symbol;Acc:HGNC:29480];perilipin 5 [Source:HGNC Symbol;Acc:HGNC:33196]",{"v":0.405348555349269,"d":"0.41"},{"v":8.95477283592481,"d":"8.95"},{"v":0.0452662019211799,"d":"0.05"},{"v":-4.46542192801669,"d":"-4.47"},{"v":4.39182767020887e-09,"d":"0.00"},{"v":4.80785352769593e-06,"d":"0.00"},"down","yes"]
["MSTRG.8181","B3GNT8","MSTRG.8181.1;ENST00000601616;ENST00000601379","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016740(transferase activity);GO:0016757(transferase activity, transferring glycosyl groups);GO:0006486(protein glycosylation);GO:0005794(Golgi apparatus);GO:0000139(Golgi membrane);GO:0008378(galactosyltransferase activity);GO:0070062(extracellular exosome);GO:0016266(O-glycan processing);GO:0008499(UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity);GO:0016262(protein N-acetylglucosaminyltransferase activity);GO:0030311(poly-N-acetyllactosamine biosynthetic process);GO:0030311(poly-N-acetyllactosamine biosynthetic process)","NA","NA","NA","UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 8 [Source:HGNC Symbol;Acc:HGNC:24139]",{"v":0.408337575089928,"d":"0.41"},{"v":9.206927,"d":"9.21"},{"v":0.0443511255264572,"d":"0.04"},{"v":-4.49488547260275,"d":"-4.49"},{"v":6.22288209178741e-09,"d":"0.00"},{"v":5.99127785871902e-06,"d":"0.00"},"down","yes"]
["MSTRG.15092","TMEM250","ENST00000418388;MSTRG.15092.1;ENST00000561457;ENST00000447934;ENST00000557985","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005654(nucleoplasm);GO:0005515(protein binding);GO:0007049(cell cycle);GO:0016032(viral process);GO:0008284(positive regulation of cell proliferation);GO:0048524(positive regulation of viral process);GO:0048524(positive regulation of viral process)","NA","NA","NA","transmembrane protein 250 [Source:HGNC Symbol;Acc:HGNC:31009]",{"v":6.7105757352381,"d":"6.71"},{"v":0.312411619591837,"d":"0.31"},{"v":21.4799172450929,"d":"21.48"},{"v":4.42491653000193,"d":"4.42"},{"v":6.46791331700276e-09,"d":"0.00"},{"v":5.99127785871902e-06,"d":"0.00"},"up","yes"]
["MSTRG.2546","MALAT1","ENST00000534336;ENST00000508832;ENST00000620465;ENST00000620902;ENST00000612781;ENST00000618925;ENST00000610481;ENST00000618132;ENST00000544868;ENST00000613376;ENST00000617791","NA","NA","NA","NA","metastasis associated lung adenocarcinoma transcript 1 (non-protein coding) [Source:HGNC Symbol;Acc:HGNC:29665]",{"v":53.2983233328384,"d":"53.30"},{"v":2.87399298572244,"d":"2.87"},{"v":18.545042941168,"d":"18.55"},{"v":4.21296170330194,"d":"4.21"},{"v":1.28129488623459E-8,"d":"0.00"},{"v":1.10209664428835e-05,"d":"0.00"},"up","yes"]
["MSTRG.12132","AC113404.3","MSTRG.12132.1;ENST00000506621","NA","NA","NA","NA",null,{"v":0.917537689295039,"d":"0.92"},{"v":18.677916,"d":"18.68"},{"v":0.0491242004351577,"d":"0.05"},{"v":-4.34742226408532,"d":"-4.35"},{"v":1.40679249813699e-08,"d":"0.00"},{"v":1.12937301750438e-05,"d":"0.00"},"down","yes"]
["MSTRG.15336","AL034397.3","MSTRG.15336.1;ENST00000618234;ENST00000621933","NA","NA","NA","NA",null,{"v":1.550927,"d":"1.55"},{"v":25.8740563134715,"d":"25.87"},{"v":0.0599413938506619,"d":"0.06"},{"v":-4.06030355774077,"d":"-4.06"},{"v":5.52371399958266e-08,"d":"0.00"},{"v":4.1572852489359e-05,"d":"0.00"},"down","yes"]
["MSTRG.1209","KIAA0040","ENST00000423313;ENST00000545251;ENST00000567124;ENST00000444639;ENST00000619513;ENST00000563563","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005515(protein binding);GO:0005515(protein binding)","NA","NA","NA","KIAA0040 [Source:HGNC Symbol;Acc:HGNC:28950]",{"v":2.1090691476061,"d":"2.11"},{"v":32.9210962818315,"d":"32.92"},{"v":0.0640643655834163,"d":"0.06"},{"v":-3.96433407772287,"d":"-3.96"},{"v":8.85655808073066e-08,"d":"0.00"},{"v":6.2735689651858e-05,"d":"0.00"},"down","yes"]
["MSTRG.2251","MRVI1","MSTRG.2251.4;MSTRG.2251.5;ENST00000547195;ENST00000529547;ENST00000423302;ENST00000526414;ENST00000529471","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0048471(perinuclear region of cytoplasm);GO:0005515(protein binding);GO:0016529(sarcoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0031095(platelet dense tubular network membrane);GO:0031095(platelet dense tubular network membrane)","04022(cGMP - PKG signaling pathway);04270(Vascular smooth muscle contraction);04270(Vascular smooth muscle contraction)","K12337","NA","murine retrovirus integration site 1 homolog [Source:HGNC Symbol;Acc:HGNC:7237]",{"v":0.817674824329382,"d":"0.82"},{"v":12.2805813791641,"d":"12.28"},{"v":0.0665827454811458,"d":"0.07"},{"v":-3.90870782980465,"d":"-3.91"},{"v":1.30742908803282e-07,"d":"0.00"},{"v":8.32806564314043e-05,"d":"0.00"},"down","yes"]
["ENSG00000105732","ZNF574","ENST00000600245;ENST00000359044;ENST00000222339;ENST00000597391","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0003677(DNA binding)","NA","NA","NA","zinc finger protein 574 [Source:HGNC Symbol;Acc:HGNC:26166]",{"v":3.28620589605658,"d":"3.29"},{"v":0.213478601371624,"d":"0.21"},{"v":15.3936079538761,"d":"15.39"},{"v":3.94425950505397,"d":"3.94"},{"v":1.31401135375908e-07,"d":"0.00"},{"v":8.32806564314043e-05,"d":"0.00"},"up","yes"]
["MSTRG.943","MLLT11","ENST00000368921;MSTRG.943.1","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0005856(cytoskeleton);GO:0045893(positive regulation of transcription, DNA-templated);GO:0005815(microtubule organizing center);GO:0003674(molecular_function);GO:0005622(intracellular);GO:0043065(positive regulation of apoptotic process);GO:0097190(apoptotic signaling pathway);GO:0097191(extrinsic apoptotic signaling pathway);GO:0090200(positive regulation of release of cytochrome c from mitochondria);GO:0097193(intrinsic apoptotic signaling pathway);GO:0051901(positive regulation of mitochondrial depolarization)","NA","NA","NA","MLLT11, transcription factor 7 cofactor [Source:HGNC Symbol;Acc:HGNC:16997]",{"v":5.01091437868812,"d":"5.01"},{"v":0.346693964886613,"d":"0.35"},{"v":14.4534225749414,"d":"14.45"},{"v":3.85333925870125,"d":"3.85"},{"v":1.66559667599859e-07,"d":"0.00"},{"v":1.00285575861875E-4,"d":"0.00"},"up","yes"]
["ENSG00000146587","RBAK","ENST00000353796;ENST00000476992;ENST00000396912","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0005654(nucleoplasm);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0005622(intracellular);GO:0008270(zinc ion binding);GO:0045892(negative regulation of transcription, DNA-templated);GO:0045892(negative regulation of transcription, DNA-templated)","NA","NA","NA","RB associated KRAB zinc finger [Source:HGNC Symbol;Acc:HGNC:17680]",{"v":0.126056599712644,"d":"0.13"},{"v":1.82606698218391,"d":"1.83"},{"v":0.0690317501726497,"d":"0.07"},{"v":-3.85659612815716,"d":"-3.86"},{"v":3.14114360067066e-07,"d":"0.00"},{"v":0.000180122148758458,"d":"0.00"},"down","yes"]
["MSTRG.13459","GNA12","ENST00000275364;ENST00000471281;ENST00000407904","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005525(GTP binding);GO:0007264(small GTPase mediated signal transduction);GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0007186(G-protein coupled receptor signaling pathway);GO:0007165(signal transduction);GO:0003924(GTPase activity);GO:0004871(signal transducer activity);GO:0005886(plasma membrane);GO:0001664(G-protein coupled receptor binding);GO:0019001(guanyl nucleotide binding);GO:0031683(G-protein beta/gamma-subunit complex binding);GO:0005925(focal adhesion);GO:0005515(protein binding);GO:0007266(Rho protein signal transduction);GO:0007188(adenylate cyclase-modulating G-protein coupled receptor signaling pathway);GO:0005834(heterotrimeric G-protein complex);GO:0016328(lateral plasma membrane);GO:0007596(blood coagulation);GO:0030168(platelet activation);GO:0032006(regulation of TOR signaling);GO:0032434(regulation of proteasomal ubiquitin-dependent protein catabolic process);GO:0031526(brush border membrane);GO:0031752(D5 dopamine receptor binding);GO:0001701(in utero embryonic development);GO:0008360(regulation of cell shape);GO:0010762(regulation of fibroblast migration);GO:0030154(cell differentiation);GO:0035556(intracellular signal transduction);GO:0042493(response to drug);GO:0042733(embryonic digit morphogenesis);GO:0042733(embryonic digit morphogenesis)","04010(MAPK signaling pathway);04072(Phospholipase D signaling pathway);04071(Sphingolipid signaling pathway);04022(cGMP - PKG signaling pathway);04810(Regulation of actin cytoskeleton);04270(Vascular smooth muscle contraction);04730(Long-term depression);05200(Pathways in cancer);05200(Pathways in cancer)","K04346","NA","G protein subunit alpha 12 [Source:HGNC Symbol;Acc:HGNC:4380]",{"v":0.390553000326797,"d":"0.39"},{"v":5.37096681143791,"d":"5.37"},{"v":0.0727155862320882,"d":"0.07"},{"v":-3.78159155782152,"d":"-3.78"},{"v":3.37022738896568e-07,"d":"0.00"},{"v":1.84473991899658E-4,"d":"0.00"},"down","yes"]
["MSTRG.13993","MTPN","ENST00000393085;ENST00000435723","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0048471(perinuclear region of cytoplasm);GO:0070062(extracellular exosome);GO:0006417(regulation of translation);GO:0051092(positive regulation of NF-kappaB transcription factor activity);GO:0030307(positive regulation of cell growth);GO:0030182(neuron differentiation);GO:0016049(cell growth);GO:0010613(positive regulation of cardiac muscle hypertrophy);GO:0016202(regulation of striated muscle tissue development);GO:0043565(sequence-specific DNA binding);GO:0006584(catecholamine metabolic process);GO:0010557(positive regulation of macromolecule biosynthetic process);GO:0021707(cerebellar granule cell differentiation);GO:0043403(skeletal muscle tissue regeneration);GO:0051146(striated muscle cell differentiation);GO:0051247(positive regulation of protein metabolic process);GO:0071260(cellular response to mechanical stimulus);GO:2000812(regulation of barbed-end actin filament capping);GO:0008290(F-actin capping protein complex);GO:0030424(axon);GO:0030424(axon)","NA","NA","NA","myotrophin [Source:HGNC Symbol;Acc:HGNC:15667]",{"v":14.9426812402649,"d":"14.94"},{"v":1.19561638092715,"d":"1.20"},{"v":12.4978893553445,"d":"12.50"},{"v":3.64361256787997,"d":"3.64"},{"v":4.68922285150596e-07,"d":"0.00"},{"v":2.45511398164499E-4,"d":"0.00"},"up","yes"]
["MSTRG.13345","ZBTB2","ENST00000325144","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:0001078(transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0000122(negative regulation of transcription from RNA polymerase II promoter)","NA","NA","NA","zinc finger and BTB domain containing 2 [Source:HGNC Symbol;Acc:HGNC:20868]",{"v":0.342514,"d":"0.34"},{"v":4.64507,"d":"4.65"},{"v":0.0737371019166557,"d":"0.07"},{"v":-3.76146547435508,"d":"-3.76"},{"v":4.91939297785395e-07,"d":"0.00"},{"v":0.000246830542663822,"d":"0.00"},"down","yes"]
["MSTRG.3389","AC068888.1","ENST00000546566;ENST00000549388;ENST00000546793;ENST00000552905","NA","NA","NA","NA",null,{"v":0.192428564212024,"d":"0.19"},{"v":2.56847298737104,"d":"2.57"},{"v":0.0749194424695835,"d":"0.07"},{"v":-3.73851602630375,"d":"-3.74"},{"v":6.12581707081619e-07,"d":"0.00"},{"v":0.000291082023008413,"d":"0.00"},"down","yes"]
["MSTRG.14822","ISCA1","ENST00000375991;ENST00000637705;ENST00000326094;ENST00000311534","GO:0046872(metal ion binding);GO:0005198(structural molecule activity);GO:0005739(mitochondrion);GO:0051536(iron-sulfur cluster binding);GO:0097428(protein maturation by iron-sulfur cluster transfer);GO:0005759(mitochondrial matrix);GO:0044281(small molecule metabolic process);GO:0008198(ferrous iron binding);GO:0016226(iron-sulfur cluster assembly);GO:0051537(2 iron, 2 sulfur cluster binding);GO:0051537(2 iron, 2 sulfur cluster binding)","NA","NA","NA","iron-sulfur cluster assembly 1 [Source:HGNC Symbol;Acc:HGNC:28660]",{"v":0.712959143648108,"d":"0.71"},{"v":9.08795836419563,"d":"9.09"},{"v":0.0784509694121174,"d":"0.08"},{"v":-3.67206491520833,"d":"-3.67"},{"v":6.28478043366446e-07,"d":"0.00"},{"v":0.000291082023008413,"d":"0.00"},"down","yes"]
["MSTRG.9296","C2orf88","ENST00000340623;ENST00000443551;ENST00000490033;ENST00000409545;ENST00000409870","GO:0034237(protein kinase A regulatory subunit binding);GO:0016020(membrane);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0005515(protein binding)","NA","NA","NA","chromosome 2 open reading frame 88 [Source:HGNC Symbol;Acc:HGNC:28191]",{"v":0.679712514924129,"d":"0.68"},{"v":7.78954903451726,"d":"7.79"},{"v":0.0872595463373,"d":"0.09"},{"v":-3.5185432166176,"d":"-3.52"},{"v":1.51730186099889e-06,"d":"0.00"},{"v":0.000676716630005505,"d":"0.00"},"down","yes"]
["MSTRG.12635","TUBB2A","ENST00000333628;ENST00000489942","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005525(GTP binding);GO:0000166(nucleotide binding);GO:0003924(GTPase activity);GO:0015630(microtubule cytoskeleton);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0005200(structural constituent of cytoskeleton);GO:0007010(cytoskeleton organization);GO:0005874(microtubule);GO:0007017(microtubule-based process);GO:0070062(extracellular exosome);GO:1903561(extracellular vesicle);GO:1903561(extracellular vesicle)","04145(Phagosome);04540(Gap junction);05130(Pathogenic Escherichia coli infection);05130(Pathogenic Escherichia coli infection)","K07375","NA","tubulin beta 2A class IIa [Source:HGNC Symbol;Acc:HGNC:12412]",{"v":14.6725775952519,"d":"14.67"},{"v":1.36420617834395,"d":"1.36"},{"v":10.7553959424692,"d":"10.76"},{"v":3.42698873110554,"d":"3.43"},{"v":1.90665023727404E-6,"d":"0.00"},{"v":0.000819995791330498,"d":"0.00"},"up","yes"]
["MSTRG.11980","BASP1","ENST00000322611;ENST00000606445;ENST00000616743","GO:0005886(plasma membrane);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016607(nuclear speck);GO:0016020(membrane);GO:0030054(cell junction);GO:0042995(cell projection);GO:0005515(protein binding);GO:0003714(transcription corepressor activity);GO:0030426(growth cone);GO:0070062(extracellular exosome);GO:0008180(COP9 signalosome);GO:0021762(substantia nigra development);GO:0019904(protein domain specific binding);GO:0044212(transcription regulatory region DNA binding);GO:0045892(negative regulation of transcription, DNA-templated);GO:0005856(cytoskeleton);GO:0031982(vesicle);GO:0072112(glomerular visceral epithelial cell differentiation);GO:0060539(diaphragm development);GO:0007356(thorax and anterior abdomen determination);GO:0008406(gonad development);GO:0060231(mesenchymal to epithelial transition);GO:0060421(positive regulation of heart growth);GO:0072075(metanephric mesenchyme development);GO:2001076(positive regulation of metanephric ureteric bud development);GO:2001076(positive regulation of metanephric ureteric bud development)","NA","NA","NA","brain abundant membrane attached signal protein 1 [Source:HGNC Symbol;Acc:HGNC:957]",{"v":7.95339158818223,"d":"7.95"},{"v":85.6003006783942,"d":"85.60"},{"v":0.0929131267665008,"d":"0.09"},{"v":-3.4279737548127,"d":"-3.43"},{"v":2.12665248011136e-06,"d":"0.00"},{"v":0.000883074109155208,"d":"0.00"},"down","yes"]
["MSTRG.9681","TP53INP2","ENST00000374810;ENST00000414082","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0045893(positive regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0005829(cytosol);GO:0006914(autophagy);GO:0031410(cytoplasmic vesicle);GO:0005515(protein binding);GO:0000045(autophagosome assembly);GO:0005776(autophagosome);GO:0010508(positive regulation of autophagy);GO:0016605(PML body);GO:0043130(ubiquitin binding);GO:0001649(osteoblast differentiation);GO:0001894(tissue homeostasis);GO:0006511(ubiquitin-dependent protein catabolic process);GO:0016236(macroautophagy);GO:1903828(negative regulation of cellular protein localization);GO:1903828(negative regulation of cellular protein localization)","04140(Autophagy - animal);04140(Autophagy - animal)","K21247","NA","tumor protein p53 inducible nuclear protein 2 [Source:HGNC Symbol;Acc:HGNC:16104]",{"v":0.785984389782403,"d":"0.79"},{"v":8.47047834862819,"d":"8.47"},{"v":0.0927910275468321,"d":"0.09"},{"v":-3.42987087945966,"d":"-3.43"},{"v":2.4380945269201E-6,"d":"0.00"},{"v":0.00097865114310573,"d":"0.00"},"down","yes"]
["ENSG00000158480","SPATA2","ENST00000289431;ENST00000422556","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0001650(fibrillar center);GO:0005515(protein binding);GO:0007275(multicellular organism development);GO:0030154(cell differentiation);GO:0007283(spermatogenesis);GO:0003674(molecular_function);GO:0003674(molecular_function)","04217(Necroptosis);04217(Necroptosis)","K17595","NA","spermatogenesis associated 2 [Source:HGNC Symbol;Acc:HGNC:14681]",{"v":0.222902630913349,"d":"0.22"},{"v":2.48929615456675,"d":"2.49"},{"v":0.089544440304711,"d":"0.09"},{"v":-3.48125232980047,"d":"-3.48"},{"v":2.95438662977958E-6,"d":"0.00"},{"v":1.11177261861893E-3,"d":"0.00"},"down","yes"]
["ENSG00000261716","AC239868.2","ENST00000564237","NA","NA","NA","NA",null,{"v":0.210383,"d":"0.21"},{"v":2.349603,"d":"2.35"},{"v":0.0895398073632013,"d":"0.09"},{"v":-3.48132697535785,"d":"-3.48"},{"v":2.95438662977958E-6,"d":"0.00"},{"v":1.11177261861893E-3,"d":"0.00"},"down","yes"]
["ENSG00000187554","TLR5","ENST00000540964;ENST00000465726;ENST00000484766;ENST00000366881","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0007165(signal transduction);GO:0004888(transmembrane signaling receptor activity);GO:0042742(defense response to bacterium);GO:0002376(immune system process);GO:0002755(MyD88-dependent toll-like receptor signaling pathway);GO:0045087(innate immune response);GO:0050707(regulation of cytokine secretion);GO:0006954(inflammatory response);GO:0005886(plasma membrane);GO:0001819(positive regulation of cytokine production);GO:0032757(positive regulation of interleukin-8 production);GO:0071260(cellular response to mechanical stimulus);GO:0034123(positive regulation of toll-like receptor signaling pathway);GO:0005149(interleukin-1 receptor binding);GO:0034146(toll-like receptor 5 signaling pathway);GO:0008584(male gonad development);GO:0045429(positive regulation of nitric oxide biosynthetic process);GO:0071222(cellular response to lipopolysaccharide);GO:0071222(cellular response to lipopolysaccharide)","04620(Toll-like receptor signaling pathway);05321(Inflammatiory bowel disease (IBD));05130(Pathogenic Escherichia coli infection);05132(Salmonella infection);05134(Legionellosis);05134(Legionellosis)","K10168","NA","toll like receptor 5 [Source:HGNC Symbol;Acc:HGNC:11851]",{"v":0.232436840928819,"d":"0.23"},{"v":2.52779400325521,"d":"2.53"},{"v":0.0919524457410273,"d":"0.09"},{"v":-3.44296824198334,"d":"-3.44"},{"v":3.14524042159946E-6,"d":"0.00"},{"v":1.14772682293639E-3,"d":"0.00"},"down","yes"]
["MSTRG.3404","CBX5","ENST00000209875;ENST00000439541;ENST00000552562;ENST00000618078;ENST00000550411","GO:0005634(nucleus);GO:0005694(chromosome);GO:0005515(protein binding);GO:0000775(chromosome, centromeric region);GO:0005654(nucleoplasm);GO:0000784(nuclear chromosome, telomeric region);GO:0016032(viral process);GO:0005635(nuclear envelope);GO:0045892(negative regulation of transcription, DNA-templated);GO:0035064(methylated histone binding);GO:0005730(nucleolus);GO:0030674(protein binding, bridging);GO:0007596(blood coagulation);GO:0017053(transcriptional repressor complex);GO:0016605(PML body);GO:0005721(pericentric heterochromatin);GO:0000118(histone deacetylase complex);GO:0070491(repressing transcription factor binding);GO:0031618(nuclear pericentric heterochromatin);GO:0003682(chromatin binding);GO:0042803(protein homodimerization activity);GO:0042826(histone deacetylase binding);GO:0000776(kinetochore);GO:0000792(heterochromatin);GO:0005720(nuclear heterochromatin);GO:0010369(chromocenter);GO:0035097(histone methyltransferase complex);GO:0035097(histone methyltransferase complex)","NA","NA","NA","chromobox 5 [Source:HGNC Symbol;Acc:HGNC:1555]",{"v":3.40763516549202,"d":"3.41"},{"v":0.34321941668883,"d":"0.34"},{"v":9.92844518636734,"d":"9.93"},{"v":3.31156780662104,"d":"3.31"},{"v":3.38552827990745e-06,"d":"0.00"},{"v":0.00119907445725428,"d":"0.00"},"up","yes"]
["MSTRG.15133","MT-TN","MSTRG.15133.1","NA","NA","NA","NA",null,{"v":108.601791,"d":"108.60"},{"v":11.425499,"d":"11.43"},{"v":9.50521206994986,"d":"9.51"},{"v":3.24871881507498,"d":"3.25"},{"v":4.61741145345791e-06,"d":"0.00"},{"v":1.58507689719751E-3,"d":"0.00"},"up","yes"]
["MSTRG.12537","DUSP1","MSTRG.12537.1;MSTRG.12537.2;ENST00000239223","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016787(hydrolase activity);GO:0004725(protein tyrosine phosphatase activity);GO:0008138(protein tyrosine/serine/threonine phosphatase activity);GO:0016791(phosphatase activity);GO:0006470(protein dephosphorylation);GO:0016311(dephosphorylation);GO:0004721(phosphoprotein phosphatase activity);GO:0005515(protein binding);GO:0017017(MAP kinase tyrosine/serine/threonine phosphatase activity);GO:0007049(cell cycle);GO:0035335(peptidyl-tyrosine dephosphorylation);GO:0006979(response to oxidative stress);GO:0042981(regulation of apoptotic process);GO:0035970(peptidyl-threonine dephosphorylation);GO:0043407(negative regulation of MAP kinase activity);GO:0043409(negative regulation of MAPK cascade);GO:0004726(non-membrane spanning protein tyrosine phosphatase activity);GO:0008330(protein tyrosine/threonine phosphatase activity);GO:0019838(growth factor binding);GO:0000188(inactivation of MAPK activity);GO:0001706(endoderm formation);GO:0009416(response to light stimulus);GO:0010033(response to organic substance);GO:0032355(response to estradiol);GO:0032526(response to retinoic acid);GO:0032870(cellular response to hormone stimulus);GO:0033574(response to testosterone);GO:0035556(intracellular signal transduction);GO:0042542(response to hydrogen peroxide);GO:0043065(positive regulation of apoptotic process);GO:0043066(negative regulation of apoptotic process);GO:0051384(response to glucocorticoid);GO:0051447(negative regulation of meiotic cell cycle);GO:0051591(response to cAMP);GO:0051592(response to calcium ion);GO:0070373(negative regulation of ERK1 and ERK2 cascade);GO:0071850(mitotic cell cycle arrest);GO:0090266(regulation of mitotic cell cycle spindle assembly checkpoint);GO:2000279(negative regulation of DNA biosynthetic process)","04010(MAPK signaling pathway);04726(Serotonergic synapse);05418(Fluid shear stress and atherosclerosis)","K21278","EC:3.1.3.16;EC:3.1.3.48","dual specificity phosphatase 1 [Source:HGNC Symbol;Acc:HGNC:3064]",{"v":10.190391715841,"d":"10.19"},{"v":99.4376706736527,"d":"99.44"},{"v":0.102480193339254,"d":"0.10"},{"v":-3.28658299230243,"d":"-3.29"},{"v":4.73864543257852e-06,"d":"0.00"},{"v":1.58507689719751E-3,"d":"0.00"},"down","yes"]
["MSTRG.13945","LRRC4","ENST00000249363;ENST00000478726;ENST00000476782","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0030054(cell junction);GO:0045202(synapse);GO:0045211(postsynaptic membrane);GO:0005737(cytoplasm);GO:0004860(protein kinase inhibitor activity);GO:0006469(negative regulation of protein kinase activity);GO:0019221(cytokine-mediated signaling pathway);GO:0046426(negative regulation of JAK-STAT cascade);GO:0050807(regulation of synapse organization);GO:0050808(synapse organization);GO:0097119(postsynaptic density protein 95 clustering);GO:0043197(dendritic spine);GO:0044309(neuron spine);GO:0060076(excitatory synapse);GO:0060076(excitatory synapse)","04514(Cell adhesion molecules (CAMs));04360(Axon guidance);04360(Axon guidance)","K16351","NA","leucine rich repeat containing 4 [Source:HGNC Symbol;Acc:HGNC:15586]",{"v":1.33619102700694,"d":"1.34"},{"v":12.8947205349356,"d":"12.89"},{"v":0.103623108650304,"d":"0.10"},{"v":-3.27058232528434,"d":"-3.27"},{"v":5.77235038533464e-06,"d":"0.00"},{"v":0.00187866603622162,"d":"0.00"},"down","yes"]
["MSTRG.3164","GABARAPL1","ENST00000266458;ENST00000541960;ENST00000545859;ENST00000540424;ENST00000542722;ENST00000537201;ENST00000546017;ENST00000535576;MSTRG.3164.4;ENST00000421801;ENST00000539408","GO:0006914(autophagy);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005794(Golgi apparatus);GO:0005783(endoplasmic reticulum);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0005874(microtubule);GO:0030659(cytoplasmic vesicle membrane);GO:0031410(cytoplasmic vesicle);GO:0032590(dendrite membrane);GO:0032839(dendrite cytoplasm);GO:0044297(cell body);GO:0005829(cytosol);GO:0000045(autophagosome assembly);GO:0000422(mitophagy);GO:0006995(cellular response to nitrogen starvation);GO:0000421(autophagosome membrane);GO:0031625(ubiquitin protein ligase binding);GO:0005776(autophagosome);GO:0005739(mitochondrion);GO:0030957(Tat protein binding);GO:0048487(beta-tubulin binding);GO:0005622(intracellular);GO:0016236(macroautophagy);GO:0050811(GABA receptor binding);GO:0097352(autophagosome maturation);GO:0097352(autophagosome maturation)","04371(Apelin signaling pathway);04068(FoxO signaling pathway);04140(Autophagy - animal);04136(Autophagy - other eukaryotes);04137(Mitophagy - animal);04621(NOD-like receptor signaling pathway);04727(GABAergic synapse);05167(Kaposi's sarcoma-associated herpesvirus infection);05167(Kaposi's sarcoma-associated herpesvirus infection)","K08341","NA","GABA type A receptor associated protein like 1 [Source:HGNC Symbol;Acc:HGNC:4068]",{"v":1.53169312726383,"d":"1.53"},{"v":14.4771404016153,"d":"14.48"},{"v":0.105800806289958,"d":"0.11"},{"v":-3.24057747285988,"d":"-3.24"},{"v":6.80841612041341e-06,"d":"0.00"},{"v":0.00215755123478996,"d":"0.00"},"down","yes"]
["MSTRG.12388","CD14","ENST00000302014;ENST00000498971;MSTRG.12388.1;ENST00000401743;ENST00000512545","GO:0016020(membrane);GO:0005794(Golgi apparatus);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0005615(extracellular space);GO:0031225(anchored component of membrane);GO:0045121(membrane raft);GO:0002376(immune system process);GO:0045087(innate immune response);GO:0006954(inflammatory response);GO:0070062(extracellular exosome);GO:0071222(cellular response to lipopolysaccharide);GO:0010008(endosome membrane);GO:0043312(neutrophil degranulation);GO:0006915(apoptotic process);GO:0002224(toll-like receptor signaling pathway);GO:0002755(MyD88-dependent toll-like receptor signaling pathway);GO:0002756(MyD88-independent toll-like receptor signaling pathway);GO:0007249(I-kappaB kinase/NF-kappaB signaling);GO:0034128(negative regulation of MyD88-independent toll-like receptor signaling pathway);GO:0034142(toll-like receptor 4 signaling pathway);GO:0035666(TRIF-dependent toll-like receptor signaling pathway);GO:0070266(necroptotic process);GO:0097190(apoptotic signaling pathway);GO:0046696(lipopolysaccharide receptor complex);GO:0007166(cell surface receptor signaling pathway);GO:0030667(secretory granule membrane);GO:0038123(toll-like receptor TLR1:TLR2 signaling pathway);GO:0038124(toll-like receptor TLR6:TLR2 signaling pathway);GO:0071223(cellular response to lipoteichoic acid);GO:0071726(cellular response to diacyl bacterial lipopeptide);GO:0071727(cellular response to triacyl bacterial lipopeptide);GO:0032760(positive regulation of tumor necrosis factor production);GO:0032729(positive regulation of interferon-gamma production);GO:0031362(anchored component of external side of plasma membrane);GO:0001530(lipopolysaccharide binding);GO:0001847(opsonin receptor activity);GO:0016019(peptidoglycan receptor activity);GO:0070891(lipoteichoic acid binding);GO:0071723(lipopeptide binding);GO:0002237(response to molecule of bacterial origin);GO:0006898(receptor-mediated endocytosis);GO:0006909(phagocytosis);GO:0009408(response to heat);GO:0009617(response to bacterium);GO:0031663(lipopolysaccharide-mediated signaling pathway);GO:0032026(response to magnesium ion);GO:0032481(positive regulation of type I interferon production);GO:0032496(response to lipopolysaccharide);GO:0034612(response to tumor necrosis factor);GO:0045471(response to ethanol);GO:0045807(positive regulation of endocytosis);GO:0050715(positive regulation of cytokine secretion);GO:0051602(response to electrical stimulus);GO:0071219(cellular response to molecule of bacterial origin);GO:1901224(positive regulation of NIK/NF-kappaB signaling);GO:2000484(positive regulation of interleukin-8 secretion);GO:0009897(external side of plasma membrane);GO:0009986(cell surface);GO:0009986(cell surface)","04010(MAPK signaling pathway);04064(NF-kappa B signaling pathway);04145(Phagosome);04810(Regulation of actin cytoskeleton);04640(Hematopoietic cell lineage);04620(Toll-like receptor signaling pathway);05202(Transcriptional misregulation in cancers);05221(Acute myeloid leukemia);05130(Pathogenic Escherichia coli infection);05132(Salmonella infection);05133(Pertussis);05134(Legionellosis);05152(Tuberculosis);05146(Amoebiasis);05146(Amoebiasis)","K04391","NA","CD14 molecule [Source:HGNC Symbol;Acc:HGNC:1628]",{"v":5.76561492266187,"d":"5.77"},{"v":53.1096743651079,"d":"53.11"},{"v":0.108560539893835,"d":"0.11"},{"v":-3.20342829418173,"d":"-3.20"},{"v":7.8088924625404e-06,"d":"0.00"},{"v":0.00241114571881824,"d":"0.00"},"down","yes"]
["MSTRG.9730","BLCAP","ENST00000373537;ENST00000432507;ENST00000397131;ENST00000397137;ENST00000613961;ENST00000397135;ENST00000411780;ENST00000456058;ENST00000397134","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005515(protein binding);GO:0007049(cell cycle);GO:0006915(apoptotic process);GO:0030262(apoptotic nuclear changes);GO:0030262(apoptotic nuclear changes)","NA","NA","NA","bladder cancer associated protein [Source:HGNC Symbol;Acc:HGNC:1055]",{"v":3.54944331300038,"d":"3.55"},{"v":0.393815075231923,"d":"0.39"},{"v":9.01296963025112,"d":"9.01"},{"v":3.17200252945274,"d":"3.17"},{"v":8.63045663883322e-06,"d":"0.00"},{"v":0.00259819897112074,"d":"0.00"},"up","yes"]
["MSTRG.6195","COTL1","ENST00000262428;MSTRG.6195.1;ENST00000567278;ENST00000567786;ENST00000564057;ENST00000564662;ENST00000561707","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0003779(actin binding);GO:0005622(intracellular);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0008150(biological_process);GO:0070062(extracellular exosome);GO:0043312(neutrophil degranulation);GO:0019899(enzyme binding);GO:0034774(secretory granule lumen);GO:1904813(ficolin-1-rich granule lumen);GO:0050832(defense response to fungus);GO:0050832(defense response to fungus)","NA","NA","NA","coactosin like F-actin binding protein 1 [Source:HGNC Symbol;Acc:HGNC:18304]",{"v":12.3005365166346,"d":"12.30"},{"v":110.977092471093,"d":"110.98"},{"v":0.110838518497307,"d":"0.11"},{"v":-3.17346876234472,"d":"-3.17"},{"v":9.0178608708602e-06,"d":"0.00"},{"v":0.00264861172211947,"d":"0.00"},"down","yes"]
["MSTRG.5962","ADGRG3","ENST00000333493;ENST00000567991;ENST00000568245;ENST00000565902;ENST00000450388;ENST00000569977;ENST00000565579","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0004930(G-protein coupled receptor activity);GO:0007186(G-protein coupled receptor signaling pathway);GO:0005886(plasma membrane);GO:0004871(signal transducer activity);GO:0007165(signal transduction);GO:0004888(transmembrane signaling receptor activity);GO:0007166(cell surface receptor signaling pathway);GO:0043312(neutrophil degranulation);GO:0035579(specific granule membrane);GO:0030334(regulation of cell migration);GO:1901223(negative regulation of NIK/NF-kappaB signaling);GO:0030183(B cell differentiation);GO:0032792(negative regulation of CREB transcription factor activity);GO:0032792(negative regulation of CREB transcription factor activity)","NA","NA","NA","adhesion G protein-coupled receptor G3 [Source:HGNC Symbol;Acc:HGNC:13728]",{"v":3.62226136846847,"d":"3.62"},{"v":32.1103997636637,"d":"32.11"},{"v":0.112806486220313,"d":"0.11"},{"v":-3.14807807175306,"d":"-3.15"},{"v":1.07162493926225E-5,"d":"0.00"},{"v":0.0030725017901419,"d":"0.00"},"down","yes"]
["ENSG00000147118","ZNF182","ENST00000376943;ENST00000396965","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0005622(intracellular);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding)","NA","NA","NA","zinc finger protein 182 [Source:HGNC Symbol;Acc:HGNC:13001]",{"v":0.257985477836632,"d":"0.26"},{"v":2.41558526484527,"d":"2.42"},{"v":0.106800402201144,"d":"0.11"},{"v":-3.22701101478602,"d":"-3.23"},{"v":1.17981808500732e-05,"d":"0.00"},{"v":0.00330403939061817,"d":"0.00"},"down","yes"]
["ENSG00000267680","ZNF224","ENST00000589060;ENST00000586978;ENST00000591551;ENST00000589870;ENST00000591511;ENST00000336976;ENST00000589680;ENST00000590614","GO:0003676(nucleic acid binding);GO:0006355(regulation of transcription, DNA-templated);GO:0005622(intracellular);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006351(transcription, DNA-templated);GO:0031965(nuclear membrane);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0005515(protein binding);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0043565(sequence-specific DNA binding);GO:0045892(negative regulation of transcription, DNA-templated);GO:0001227(transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding);GO:0017053(transcriptional repressor complex);GO:0017053(transcriptional repressor complex)","NA","NA","NA","zinc finger protein 224 [Source:HGNC Symbol;Acc:HGNC:13017]",{"v":2.10726351646959,"d":"2.11"},{"v":0.239755662302928,"d":"0.24"},{"v":8.78921271860137,"d":"8.79"},{"v":3.13573394377173,"d":"3.14"},{"v":1.23603684912418E-5,"d":"0.00"},{"v":3.38280812208031E-3,"d":"0.00"},"up","yes"]
["ENSG00000004799","PDK4","ENST00000498190;ENST00000473796;ENST00000468445;ENST00000473301;ENST00000005178","GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0006468(protein phosphorylation);GO:0005739(mitochondrion);GO:0005759(mitochondrial matrix);GO:0005975(carbohydrate metabolic process);GO:0006885(regulation of pH);GO:0008286(insulin receptor signaling pathway);GO:0010510(regulation of acetyl-CoA biosynthetic process from pyruvate);GO:0010565(regulation of cellular ketone metabolic process);GO:0010906(regulation of glucose metabolic process);GO:0042304(regulation of fatty acid biosynthetic process);GO:0042593(glucose homeostasis);GO:0042594(response to starvation);GO:0045124(regulation of bone resorption);GO:0046320(regulation of fatty acid oxidation);GO:0005743(mitochondrial inner membrane);GO:0009267(cellular response to starvation);GO:0006006(glucose metabolic process);GO:0004672(protein kinase activity);GO:0071398(cellular response to fatty acid);GO:0072593(reactive oxygen species metabolic process);GO:2000811(negative regulation of anoikis);GO:0004740(pyruvate dehydrogenase (acetyl-transferring) kinase activity);GO:0004740(pyruvate dehydrogenase (acetyl-transferring) kinase activity)","NA","NA","NA","pyruvate dehydrogenase kinase 4 [Source:HGNC Symbol;Acc:HGNC:8812]",{"v":0.224994206019031,"d":"0.22"},{"v":2.10253462049126,"d":"2.10"},{"v":0.107010939951353,"d":"0.11"},{"v":-3.22416980100139,"d":"-3.22"},{"v":1.28255260902179E-5,"d":"0.00"},{"v":0.00343211078174231,"d":"0.00"},"down","yes"]
["ENSG00000111261","MANSC1","ENST00000535902;ENST00000545735;ENST00000396349","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016021(integral component of membrane)","NA","NA","NA","MANSC domain containing 1 [Source:HGNC Symbol;Acc:HGNC:25505]",{"v":0.41047231521197,"d":"0.41"},{"v":3.63447942809643,"d":"3.63"},{"v":0.112938406540096,"d":"0.11"},{"v":-3.14639191344861,"d":"-3.15"},{"v":1.3132026516609E-5,"d":"0.00"},{"v":0.00343773615897838,"d":"0.00"},"down","yes"]
["MSTRG.7637","GNG7","ENST00000382159;ENST00000587867","GO:0016020(membrane);GO:0007186(G-protein coupled receptor signaling pathway);GO:0004871(signal transducer activity);GO:0005886(plasma membrane);GO:0007165(signal transduction);GO:0005834(heterotrimeric G-protein complex);GO:0070062(extracellular exosome);GO:0008277(regulation of G-protein coupled receptor protein signaling pathway);GO:0071377(cellular response to glucagon stimulus);GO:0071377(cellular response to glucagon stimulus)","04014(Ras signaling pathway);04371(Apelin signaling pathway);04151(PI3K-Akt signaling pathway);04062(Chemokine signaling pathway);04926(Relaxin signaling pathway);04724(Glutamatergic synapse);04727(GABAergic synapse);04725(Cholinergic synapse);04728(Dopaminergic synapse);04726(Serotonergic synapse);04723(Retrograde endocannabinoid signaling);04740(Olfactory transduction);04713(Circadian entrainment);05200(Pathways in cancer);05032(Morphine addiction);05034(Alcoholism);05167(Kaposi's sarcoma-associated herpesvirus infection);05167(Kaposi's sarcoma-associated herpesvirus infection)","K04543","NA","G protein subunit gamma 7 [Source:HGNC Symbol;Acc:HGNC:4410]",{"v":0.346344627713221,"d":"0.35"},{"v":3.0709261992984,"d":"3.07"},{"v":0.11278181409646,"d":"0.11"},{"v":-3.14839364087453,"d":"-3.15"},{"v":1.48401705411774E-5,"d":"0.00"},{"v":0.00374466518398293,"d":"0.00"},"down","yes"]
["MSTRG.2130","RHOG","ENST00000351018;ENST00000533217;MSTRG.2130.2;ENST00000396979;ENST00000396978","GO:0016020(membrane);GO:0005525(GTP binding);GO:0007264(small GTPase mediated signal transduction);GO:0000166(nucleotide binding);GO:0003924(GTPase activity);GO:0005622(intracellular);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0005925(focal adhesion);GO:0005789(endoplasmic reticulum membrane);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0051056(regulation of small GTPase mediated signal transduction);GO:0090630(activation of GTPase activity);GO:0043312(neutrophil degranulation);GO:0007266(Rho protein signal transduction);GO:0030667(secretory granule membrane);GO:0030168(platelet activation);GO:0060326(cell chemotaxis);GO:0045893(positive regulation of transcription, DNA-templated);GO:0008284(positive regulation of cell proliferation);GO:0090004(positive regulation of establishment of protein localization to plasma membrane);GO:0016601(Rac protein signal transduction);GO:0030036(actin cytoskeleton organization);GO:1900027(regulation of ruffle assembly);GO:1900027(regulation of ruffle assembly)","05132(Salmonella infection);05131(Shigellosis);05100(Bacterial invasion of epithelial cells);05100(Bacterial invasion of epithelial cells)","K07863","NA","ras homolog family member G [Source:HGNC Symbol;Acc:HGNC:672]",{"v":46.623426157688,"d":"46.62"},{"v":5.66250891021324,"d":"5.66"},{"v":8.23370468761563,"d":"8.23"},{"v":3.04154170547814,"d":"3.04"},{"v":1.49264182719798E-5,"d":"0.00"},{"v":0.00374466518398293,"d":"0.00"},"up","yes"]
["ENSG00000112486","CCR6","ENST00000349984;ENST00000341935;ENST00000400926","GO:0005622(intracellular);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0004930(G-protein coupled receptor activity);GO:0007186(G-protein coupled receptor signaling pathway);GO:0005886(plasma membrane);GO:0004871(signal transducer activity);GO:0007165(signal transduction);GO:0006955(immune response);GO:0004950(chemokine receptor activity);GO:0016493(C-C chemokine receptor activity);GO:0006935(chemotaxis);GO:0070098(chemokine-mediated signaling pathway);GO:0005515(protein binding);GO:0005887(integral component of plasma membrane);GO:0072678(T cell migration);GO:0004872(receptor activity);GO:0009986(cell surface);GO:0006928(movement of cell or subcellular component);GO:0002407(dendritic cell chemotaxis);GO:0060326(cell chemotaxis);GO:0097225(sperm midpiece);GO:0019722(calcium-mediated signaling);GO:0007204(positive regulation of cytosolic calcium ion concentration);GO:0006968(cellular defense response);GO:0097524(sperm plasma membrane);GO:0006959(humoral immune response);GO:0002523(leukocyte migration involved in inflammatory response);GO:0036126(sperm flagellum);GO:0072676(lymphocyte migration);GO:0019957(C-C chemokine binding);GO:0010634(positive regulation of epithelial cell migration);GO:0048290(isotype switching to IgA isotypes);GO:0060474(positive regulation of flagellated sperm motility involved in capacitation);GO:0072679(thymocyte migration);GO:1904155(DN2 thymocyte differentiation);GO:1904156(DN3 thymocyte differentiation);GO:2000404(regulation of T cell migration);GO:2000510(positive regulation of dendritic cell chemotaxis);GO:0097228(sperm principal piece);GO:0097228(sperm principal piece)","04060(Cytokine-cytokine receptor interaction);04062(Chemokine signaling pathway);04062(Chemokine signaling pathway)","K04181","NA","C-C motif chemokine receptor 6 [Source:HGNC Symbol;Acc:HGNC:1607]",{"v":1.70002206436346,"d":"1.70"},{"v":0.195141822527212,"d":"0.20"},{"v":8.71172587376238,"d":"8.71"},{"v":3.12295855841826,"d":"3.12"},{"v":1.62240341418073E-5,"d":"0.00"},{"v":3.98713916603354E-3,"d":"0.00"},"up","yes"]
["MSTRG.5520","EME2","ENST00000570069;ENST00000568449;ENST00000561903;ENST00000561564","GO:0005634(nucleus);GO:0016787(hydrolase activity);GO:0003677(DNA binding);GO:0006281(DNA repair);GO:0090305(nucleic acid phosphodiester bond hydrolysis);GO:0006310(DNA recombination);GO:0006974(cellular response to DNA damage stimulus);GO:0004519(endonuclease activity);GO:0004518(nuclease activity);GO:0000712(resolution of meiotic recombination intermediates);GO:0031297(replication fork processing);GO:0000790(nuclear chromatin);GO:0008821(crossover junction endodeoxyribonuclease activity);GO:0006302(double-strand break repair);GO:0031573(intra-S DNA damage checkpoint);GO:0048476(Holliday junction resolvase complex);GO:0048476(Holliday junction resolvase complex)","03460(Fanconi anemia pathway);03460(Fanconi anemia pathway)","K10883","NA","essential meiotic structure-specific endonuclease subunit 2 [Source:HGNC Symbol;Acc:HGNC:27289]",{"v":0.127196983933999,"d":"0.13"},{"v":1.1198981524099,"d":"1.12"},{"v":0.113579064007102,"d":"0.11"},{"v":-3.13823116705823,"d":"-3.14"},{"v":1.96517861753375e-05,"d":"0.00"},{"v":0.00473293618246829,"d":"0.00"},"down","yes"]
["MSTRG.14241","TNFRSF10C","ENST00000356864;ENST00000517558;ENST00000518135;ENST00000397703;ENST00000520607","GO:0016020(membrane);GO:0005886(plasma membrane);GO:0006915(apoptotic process);GO:0031225(anchored component of membrane);GO:0006955(immune response);GO:0006954(inflammatory response);GO:0097190(apoptotic signaling pathway);GO:0005887(integral component of plasma membrane);GO:0045569(TRAIL binding);GO:0033209(tumor necrosis factor-mediated signaling pathway);GO:0007165(signal transduction);GO:0005031(tumor necrosis factor-activated receptor activity);GO:0007275(multicellular organism development);GO:0032496(response to lipopolysaccharide);GO:0042127(regulation of cell proliferation);GO:0042981(regulation of apoptotic process);GO:0043154(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process);GO:0004888(transmembrane signaling receptor activity);GO:0004888(transmembrane signaling receptor activity)","04060(Cytokine-cytokine receptor interaction);04210(Apoptosis);04217(Necroptosis);04650(Natural killer cell mediated cytotoxicity);05162(Measles);05164(Influenza A);05164(Influenza A)","K04722","NA","TNF receptor superfamily member 10c [Source:HGNC Symbol;Acc:HGNC:11906]",{"v":12.174302039619,"d":"12.17"},{"v":99.531420432,"d":"99.53"},{"v":0.122316168972355,"d":"0.12"},{"v":-3.03131296858238,"d":"-3.03"},{"v":2.01838372674886e-05,"d":"0.00"},{"v":0.0047657601642176,"d":"0.00"},"down","yes"]
["ENSG00000269001","AC092070.2","ENST00000598377;ENST00000597550","NA","NA","NA","NA",null,{"v":1.52929050616979,"d":"1.53"},{"v":0.179906894126357,"d":"0.18"},{"v":8.50045526935559,"d":"8.50"},{"v":3.08754011151532,"d":"3.09"},{"v":2.10083450076514e-05,"d":"0.00"},{"v":0.00486504789581035,"d":"0.00"},"up","yes"]
["MSTRG.12372","PURA","ENST00000331327;ENST00000502351;ENST00000505703","GO:0003723(RNA binding);GO:0005634(nucleus);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0005515(protein binding);GO:0030154(cell differentiation);GO:0045892(negative regulation of transcription, DNA-templated);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0042127(regulation of cell proliferation);GO:0008134(transcription factor binding);GO:0003705(transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding);GO:0003697(single-stranded DNA binding);GO:0005662(DNA replication factor A complex);GO:0006270(DNA replication initiation);GO:0000784(nuclear chromosome, telomeric region);GO:0003691(double-stranded telomeric DNA binding);GO:0006268(DNA unwinding involved in DNA replication);GO:0000900(translation repressor activity, nucleic acid binding);GO:0003690(double-stranded DNA binding);GO:0032422(purine-rich negative regulatory element binding);GO:0046332(SMAD binding);GO:0007399(nervous system development);GO:0008284(positive regulation of cell proliferation);GO:0017148(negative regulation of translation);GO:0005737(cytoplasm);GO:0030425(dendrite);GO:0043025(neuronal cell body);GO:0043025(neuronal cell body)","NA","NA","NA","purine rich element binding protein A [Source:HGNC Symbol;Acc:HGNC:9701]",{"v":0.100969353631514,"d":"0.10"},{"v":0.861055950020517,"d":"0.86"},{"v":0.117262244839151,"d":"0.12"},{"v":-3.09218951418215,"d":"-3.09"},{"v":2.281012558144e-05,"d":"0.00"},{"v":0.00518263268399435,"d":"0.01"},"down","yes"]
["MSTRG.9818","CEBPB","ENST00000303004","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005654(nucleoplasm);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0042803(protein homodimerization activity);GO:0005515(protein binding);GO:0030154(cell differentiation);GO:0042742(defense response to bacterium);GO:0006954(inflammatory response);GO:0006955(immune response);GO:0032753(positive regulation of interleukin-4 production);GO:0006366(transcription from RNA polymerase II promoter);GO:0046982(protein heterodimerization activity);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0034976(response to endoplasmic reticulum stress);GO:0070059(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress);GO:1990440(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress);GO:0045600(positive regulation of fat cell differentiation);GO:0042130(negative regulation of T cell proliferation);GO:0003705(transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding);GO:0001541(ovarian follicle development);GO:0006953(acute-phase response);GO:0045670(regulation of osteoclast differentiation);GO:0000977(RNA polymerase II regulatory region sequence-specific DNA binding);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:0000979(RNA polymerase II core promoter sequence-specific DNA binding);GO:0000981(RNA polymerase II transcription factor activity, sequence-specific DNA binding);GO:0001077(transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0003682(chromatin binding);GO:0008134(transcription factor binding);GO:0019900(kinase binding);GO:0035035(histone acetyltransferase binding);GO:0035259(glucocorticoid receptor binding);GO:0042826(histone deacetylase binding);GO:0043565(sequence-specific DNA binding);GO:0044212(transcription regulatory region DNA binding);GO:0044389(ubiquitin-like protein ligase binding);GO:0001889(liver development);GO:0001892(embryonic placenta development);GO:0007613(memory);GO:0030182(neuron differentiation);GO:0032496(response to lipopolysaccharide);GO:0033598(mammary gland epithelial cell proliferation);GO:0043524(negative regulation of neuron apoptotic process);GO:0045408(regulation of interleukin-6 biosynthetic process);GO:0045444(fat cell differentiation);GO:0045669(positive regulation of osteoblast differentiation);GO:0045892(negative regulation of transcription, DNA-templated);GO:0045893(positive regulation of transcription, DNA-templated);GO:0050873(brown fat cell differentiation);GO:0060644(mammary gland epithelial cell differentiation);GO:0060850(regulation of transcription involved in cell fate commitment);GO:0071222(cellular response to lipopolysaccharide);GO:0071230(cellular response to amino acid stimulus);GO:0071347(cellular response to interleukin-1);GO:0071407(cellular response to organic cyclic compound);GO:0072574(hepatocyte proliferation);GO:0097421(liver regeneration);GO:0000779(condensed chromosome, centromeric region);GO:0000790(nuclear chromatin);GO:0016363(nuclear matrix);GO:0036488(CHOP-C/EBP complex)","04668(TNF signaling pathway);04657(IL-17 signaling pathway);05202(Transcriptional misregulation in cancers);05152(Tuberculosis)","K10048","NA","CCAAT/enhancer binding protein beta [Source:HGNC Symbol;Acc:HGNC:1834]",{"v":17.17054,"d":"17.17"},{"v":2.242085,"d":"2.24"},{"v":7.65829127798455,"d":"7.66"},{"v":2.93702253317217,"d":"2.94"},{"v":2.78215575305893e-05,"d":"0.00"},{"v":0.00620420732932142,"d":"0.01"},"up","yes"]
["MSTRG.4412","FBXO34","ENST00000313833;ENST00000557647;ENST00000555280","GO:0005515(protein binding);GO:0005515(protein binding)","NA","NA","NA","F-box protein 34 [Source:HGNC Symbol;Acc:HGNC:20201]",{"v":2.68194918751512,"d":"2.68"},{"v":0.345554901524316,"d":"0.35"},{"v":7.76128243496033,"d":"7.76"},{"v":2.9562950557234,"d":"2.96"},{"v":3.30482417000896e-05,"d":"0.00"},{"v":0.00723576230095416,"d":"0.01"},"up","yes"]
["MSTRG.1271","NEK7","ENST00000367385;ENST00000544035;ENST00000538004;ENST00000417895;ENST00000493790;ENST00000442588;ENST00000391974","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0005654(nucleoplasm);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0005856(cytoskeleton);GO:0005874(microtubule);GO:0000922(spindle pole);GO:0005815(microtubule organizing center);GO:0007346(regulation of mitotic cell cycle);GO:0000910(cytokinesis);GO:0032212(positive regulation of telomere maintenance via telomerase);GO:0051973(positive regulation of telomerase activity);GO:1904355(positive regulation of telomere capping);GO:0051225(spindle assembly);GO:0051225(spindle assembly)","04621(NOD-like receptor signaling pathway);04621(NOD-like receptor signaling pathway)","K20876","EC:2.7.11.1","NIMA related kinase 7 [Source:HGNC Symbol;Acc:HGNC:13386]",{"v":1.57949093527803,"d":"1.58"},{"v":12.1156445978122,"d":"12.12"},{"v":0.130367882825091,"d":"0.13"},{"v":-2.93933960105484,"d":"-2.94"},{"v":3.57285259048342e-05,"d":"0.00"},{"v":0.00768290908832167,"d":"0.01"},"down","yes"]
["MSTRG.12358","MZB1","ENST00000302125;ENST00000503120;ENST00000511979;ENST00000503351;ENST00000509591","GO:0005737(cytoplasm);GO:0005783(endoplasmic reticulum);GO:0005576(extracellular region);GO:0006915(apoptotic process);GO:0005788(endoplasmic reticulum lumen);GO:0042127(regulation of cell proliferation);GO:0033622(integrin activation);GO:0034663(endoplasmic reticulum chaperone complex);GO:0002642(positive regulation of immunoglobulin biosynthetic process);GO:0030888(regulation of B cell proliferation);GO:2001274(negative regulation of glucose import in response to insulin stimulus);GO:0008284(positive regulation of cell proliferation);GO:0008284(positive regulation of cell proliferation)","NA","NA","NA","marginal zone B and B1 cell specific protein [Source:HGNC Symbol;Acc:HGNC:30125]",{"v":6.40936506203256,"d":"6.41"},{"v":0.848628234051914,"d":"0.85"},{"v":7.55261821944104,"d":"7.55"},{"v":2.91697686131223,"d":"2.92"},{"v":3.85852184240596e-05,"d":"0.00"},{"v":0.008151635092325,"d":"0.01"},"up","yes"]
["MSTRG.8918","IGKV1D-39","ENST00000448155","GO:0016020(membrane);GO:0005886(plasma membrane);GO:0005576(extracellular region);GO:0006508(proteolysis);GO:0006955(immune response);GO:0002376(immune system process);GO:0003823(antigen binding);GO:0002250(adaptive immune response);GO:0004252(serine-type endopeptidase activity);GO:0006898(receptor-mediated endocytosis);GO:0006956(complement activation);GO:0006958(complement activation, classical pathway);GO:0030449(regulation of complement activation);GO:0038095(Fc-epsilon receptor signaling pathway);GO:0038096(Fc-gamma receptor signaling pathway involved in phagocytosis);GO:0050776(regulation of immune response);GO:0050900(leukocyte migration)","NA","NA","NA","immunoglobulin kappa variable 1D-39 [Source:HGNC Symbol;Acc:HGNC:5756]",{"v":20.265753,"d":"20.27"},{"v":2.668268,"d":"2.67"},{"v":7.59509651954002,"d":"7.60"},{"v":2.92506829881254,"d":"2.93"},{"v":4.15247347037496e-05,"d":"0.00"},{"v":0.00862139405694057,"d":"0.01"},"up","yes"]
["MSTRG.3113","CLEC4E;AC092746.1","ENST00000446457;ENST00000446809;ENST00000537698;MSTRG.3113.1;ENST00000542819;ENST00000450725;ENST00000299663;MSTRG.3113.2;ENST00000545274","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0030246(carbohydrate binding);GO:0002376(immune system process);GO:0005886(plasma membrane);GO:0002223(stimulatory C-type lectin receptor signaling pathway);GO:0004872(receptor activity);GO:0002292(T cell differentiation involved in immune response);GO:0006955(immune response);GO:0038094(Fc-gamma receptor signaling pathway);GO:0042742(defense response to bacterium);GO:0045087(innate immune response);GO:0050715(positive regulation of cytokine secretion);GO:0050715(positive regulation of cytokine secretion)","05152(Tuberculosis);05152(Tuberculosis)","K10059","NA","C-type lectin domain family 4 member E [Source:HGNC Symbol;Acc:HGNC:14555]",{"v":1.37626783794338,"d":"1.38"},{"v":10.3322709153921,"d":"10.33"},{"v":0.133200905126591,"d":"0.13"},{"v":-2.9083242090457,"d":"-2.91"},{"v":4.31785371569821e-05,"d":"0.00"},{"v":0.00881281261770133,"d":"0.01"},"down","yes"]
["ENSG00000170949","ZNF160","ENST00000599247;ENST00000599056;ENST00000600924;ENST00000596388;ENST00000601421;ENST00000599637;ENST00000597112;ENST00000429604;ENST00000355147;ENST00000594760;ENST00000599729;ENST00000418871;ENST00000601982;ENST00000596966;ENST00000599980","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0005622(intracellular);GO:0030097(hemopoiesis);GO:0030097(hemopoiesis)","NA","NA","NA","zinc finger protein 160 [Source:HGNC Symbol;Acc:HGNC:12948]",{"v":0.233093842321701,"d":"0.23"},{"v":1.77194504782047,"d":"1.77"},{"v":0.131546879858612,"d":"0.13"},{"v":-2.92635106505244,"d":"-2.93"},{"v":4.8859750933678E-5,"d":"0.00"},{"v":0.00980615201238917,"d":"0.01"},"down","yes"]
["MSTRG.1301","RABIF","ENST00000367262","GO:0006810(transport);GO:0015031(protein transport);GO:0007264(small GTPase mediated signal transduction);GO:0046872(metal ion binding);GO:0008270(zinc ion binding);GO:0043547(positive regulation of GTPase activity);GO:0005515(protein binding);GO:0005085(guanyl-nucleotide exchange factor activity);GO:0016020(membrane);GO:0005829(cytosol);GO:0061025(membrane fusion);GO:0006892(post-Golgi vesicle-mediated transport)","NA","NA","NA","RAB interacting factor [Source:HGNC Symbol;Acc:HGNC:9797]",{"v":2.383778,"d":"2.38"},{"v":0.316289,"d":"0.32"},{"v":7.53670851657819,"d":"7.54"},{"v":2.91393459728955,"d":"2.91"},{"v":5.09488161242838e-05,"d":"0.00"},{"v":0.0100577974388299,"d":"0.01"},"up","yes"]
["MSTRG.11892","TLR2","MSTRG.11892.2;MSTRG.11892.1;ENST00000260010;MSTRG.11892.3","GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0005737(cytoplasm);GO:0050729(positive regulation of inflammatory response);GO:0032755(positive regulation of interleukin-6 production);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0007165(signal transduction);GO:0005794(Golgi apparatus);GO:0005515(protein binding);GO:0006954(inflammatory response);GO:0031410(cytoplasmic vesicle);GO:0045121(membrane raft);GO:0002376(immune system process);GO:0002755(MyD88-dependent toll-like receptor signaling pathway);GO:0045087(innate immune response);GO:0050707(regulation of cytokine secretion);GO:0005886(plasma membrane);GO:0071723(lipopeptide binding);GO:0001666(response to hypoxia);GO:0001774(microglial cell activation);GO:0002224(toll-like receptor signaling pathway);GO:0002237(response to molecule of bacterial origin);GO:0006691(leukotriene metabolic process);GO:0008285(negative regulation of cell proliferation);GO:0009636(response to toxic substance);GO:0032289(central nervous system myelin formation);GO:0032493(response to bacterial lipoprotein);GO:0032496(response to lipopolysaccharide);GO:0032570(response to progesterone);GO:0032733(positive regulation of interleukin-10 production);GO:0032868(response to insulin);GO:0034134(toll-like receptor 2 signaling pathway);GO:0046209(nitric oxide metabolic process);GO:0048714(positive regulation of oligodendrocyte differentiation);GO:0070542(response to fatty acid);GO:0009986(cell surface);GO:0042995(cell projection);GO:0044297(cell body);GO:0030670(phagocytic vesicle membrane);GO:0010628(positive regulation of gene expression);GO:0004872(receptor activity);GO:0005887(integral component of plasma membrane);GO:0050830(defense response to Gram-positive bacterium);GO:0043312(neutrophil degranulation);GO:0006955(immune response);GO:0051092(positive regulation of NF-kappaB transcription factor activity);GO:0006915(apoptotic process);GO:0001530(lipopolysaccharide binding);GO:0001875(lipopolysaccharide receptor activity);GO:0007252(I-kappaB phosphorylation);GO:0032722(positive regulation of chemokine production);GO:0032728(positive regulation of interferon-beta production);GO:0032735(positive regulation of interleukin-12 production);GO:0032757(positive regulation of interleukin-8 production);GO:0032760(positive regulation of tumor necrosis factor production);GO:0042346(positive regulation of NF-kappaB import into nucleus);GO:0051770(positive regulation of nitric-oxide synthase biosynthetic process);GO:0031226(intrinsic component of plasma membrane);GO:0030667(secretory granule membrane);GO:0106003(amyloid-beta complex);GO:0008329(signaling pattern recognition receptor activity);GO:0030177(positive regulation of Wnt signaling pathway);GO:0046982(protein heterodimerization activity);GO:0034123(positive regulation of toll-like receptor signaling pathway);GO:0032403(protein complex binding);GO:0035325(Toll-like receptor binding);GO:0042497(triacyl lipopeptide binding);GO:0042834(peptidoglycan binding);GO:0001775(cell activation);GO:0002374(cytokine secretion involved in immune response);GO:0007612(learning);GO:0014005(microglia development);GO:0031663(lipopolysaccharide-mediated signaling pathway);GO:0032613(interleukin-10 production);GO:0032640(tumor necrosis factor production);GO:0032741(positive regulation of interleukin-18 production);GO:0038123(toll-like receptor TLR1:TLR2 signaling pathway);GO:0038124(toll-like receptor TLR6:TLR2 signaling pathway);GO:0042495(detection of triacyl bacterial lipopeptide);GO:0042496(detection of diacyl bacterial lipopeptide);GO:0050765(negative regulation of phagocytosis);GO:0051964(negative regulation of synapse assembly);GO:0071221(cellular response to bacterial lipopeptide);GO:0071223(cellular response to lipoteichoic acid);GO:0071726(cellular response to diacyl bacterial lipopeptide);GO:0071727(cellular response to triacyl bacterial lipopeptide);GO:2000484(positive regulation of interleukin-8 secretion);GO:0035354(Toll-like receptor 1-Toll-like receptor 2 protein complex)","04151(PI3K-Akt signaling pathway);04145(Phagosome);04620(Toll-like receptor signaling pathway);05205(Proteoglycans in cancer);05323(Rheumatoid arthritis);05321(Inflammatiory bowel disease (IBD));05134(Legionellosis);05152(Tuberculosis);05162(Measles);05161(Hepatitis B);05168(Herpes simplex infection);05146(Amoebiasis);05144(Malaria);05145(Toxoplasmosis);05140(Leishmaniasis);05142(Chagas disease (American trypanosomiasis))","K10159","NA","toll like receptor 2 [Source:HGNC Symbol;Acc:HGNC:11848]",{"v":2.92184125152267,"d":"2.92"},{"v":20.9165672483645,"d":"20.92"},{"v":0.139690285543921,"d":"0.14"},{"v":-2.83969639972996,"d":"-2.84"},{"v":5.74705164728881e-05,"d":"0.00"},{"v":0.0111622574091374,"d":"0.01"},"down","yes"]
["MSTRG.1207","MRPS14","ENST00000476371;ENST00000498253;ENST00000367677","GO:0003723(RNA binding);GO:0006412(translation);GO:0030529(intracellular ribonucleoprotein complex);GO:0005622(intracellular);GO:0003735(structural constituent of ribosome);GO:0005840(ribosome);GO:0005739(mitochondrion);GO:0005743(mitochondrial inner membrane);GO:0070125(mitochondrial translational elongation);GO:0070126(mitochondrial translational termination);GO:0005763(mitochondrial small ribosomal subunit);GO:0005761(mitochondrial ribosome);GO:0005761(mitochondrial ribosome)","03010(Ribosome);03010(Ribosome)","K02954","NA","mitochondrial ribosomal protein S14 [Source:HGNC Symbol;Acc:HGNC:14049]",{"v":0.336427398226677,"d":"0.34"},{"v":2.52697853238242,"d":"2.53"},{"v":0.133134252592758,"d":"0.13"},{"v":-2.90904630133614,"d":"-2.91"},{"v":6.31971609231166E-5,"d":"0.00"},{"v":0.0120796859021614,"d":"0.01"},"down","yes"]
["MSTRG.14794","LINC01506","ENST00000432148;ENST00000446290","NA","NA","NA","NA","long intergenic non-protein coding RNA 1506 [Source:HGNC Symbol;Acc:HGNC:51187]",{"v":1.16417281178707,"d":"1.16"},{"v":9.08485992585551,"d":"9.08"},{"v":0.128144277543987,"d":"0.13"},{"v":-2.96415904031753,"d":"-2.96"},{"v":6.48582631640509e-05,"d":"0.00"},{"v":0.012203487578461,"d":"0.01"},"down","yes"]
["MSTRG.1462","EXOC8","ENST00000366645","GO:0006810(transport);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0015031(protein transport);GO:0005829(cytosol);GO:0006887(exocytosis);GO:0000145(exocyst);GO:0042995(cell projection);GO:0005515(protein binding);GO:0048471(perinuclear region of cytoplasm);GO:0005886(plasma membrane);GO:0030426(growth cone);GO:0022617(extracellular matrix disassembly);GO:0005770(late endosome);GO:0017160(Ral GTPase binding);GO:0016241(regulation of macroautophagy);GO:0051601(exocyst localization);GO:0007032(endosome organization);GO:0001927(exocyst assembly);GO:0034613(cellular protein localization)","NA","NA","NA","exocyst complex component 8 [Source:HGNC Symbol;Acc:HGNC:24659]",{"v":2.76689,"d":"2.77"},{"v":0.404375,"d":"0.40"},{"v":6.84238639876352,"d":"6.84"},{"v":2.77449957733579,"d":"2.77"},{"v":7.54233996564991e-05,"d":"0.00"},{"v":0.0139730550563625,"d":"0.01"},"up","yes"]
["ENSG00000198064","NPIPB13","ENST00000564502;ENST00000568053;ENST00000562937;ENST00000618637;ENST00000520915;ENST00000543463;ENST00000564219","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005654(nucleoplasm);GO:0005654(nucleoplasm)","NA","NA","NA","nuclear pore complex interacting protein family, member B13 [Source:HGNC Symbol;Acc:HGNC:41989]",{"v":1.54652007920031,"d":"1.55"},{"v":0.212188304113802,"d":"0.21"},{"v":7.28843225200043,"d":"7.29"},{"v":2.86560852298808,"d":"2.87"},{"v":7.78017165099051e-05,"d":"0.00"},{"v":0.0140172846959204,"d":"0.01"},"up","yes"]
["MSTRG.11543","MED28","ENST00000237380;ENST00000506409","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005654(nucleoplasm);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003779(actin binding);GO:0005515(protein binding);GO:0016592(mediator complex);GO:0019827(stem cell population maintenance);GO:0051151(negative regulation of smooth muscle cell differentiation);GO:0005856(cytoskeleton);GO:0030864(cortical actin cytoskeleton);GO:0030864(cortical actin cytoskeleton)","NA","NA","NA","mediator complex subunit 28 [Source:HGNC Symbol;Acc:HGNC:24628]",{"v":3.6788982390275,"d":"3.68"},{"v":0.548930428064105,"d":"0.55"},{"v":6.70193899070553,"d":"6.70"},{"v":2.74457855341687,"d":"2.74"},{"v":7.83482623093094e-05,"d":"0.00"},{"v":0.0140172846959204,"d":"0.01"},"up","yes"]
["MSTRG.8874","VAMP5","ENST00000306384;ENST00000462451","GO:0048471(perinuclear region of cytoplasm);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016192(vesicle-mediated transport);GO:0005794(Golgi apparatus);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0007275(multicellular organism development);GO:0030154(cell differentiation);GO:0006906(vesicle fusion);GO:0070062(extracellular exosome);GO:0012505(endomembrane system);GO:0007517(muscle organ development);GO:0000149(SNARE binding);GO:0005484(SNAP receptor activity);GO:0031201(SNARE complex);GO:0006887(exocytosis);GO:0009986(cell surface);GO:0005770(late endosome);GO:0014704(intercalated disc);GO:0007519(skeletal muscle tissue development);GO:0043001(Golgi to plasma membrane protein transport);GO:0005887(integral component of plasma membrane);GO:0030659(cytoplasmic vesicle membrane);GO:0031301(integral component of organelle membrane);GO:0031301(integral component of organelle membrane)","04130(SNARE interactions in vesicular transport);04130(SNARE interactions in vesicular transport)","K08514","NA","vesicle associated membrane protein 5 [Source:HGNC Symbol;Acc:HGNC:12646]",{"v":1.57784952258852,"d":"1.58"},{"v":11.305136962149,"d":"11.31"},{"v":0.139569253152028,"d":"0.14"},{"v":-2.84094694138251,"d":"-2.84"},{"v":7.91542401031877e-05,"d":"0.00"},{"v":0.0140172846959204,"d":"0.01"},"down","yes"]
["MSTRG.10810","CTDSPL","ENST00000443503;ENST00000273179;ENST00000436654;ENST00000310189;ENST00000486978;ENST00000435525","GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0016787(hydrolase activity);GO:0016791(phosphatase activity);GO:0016311(dephosphorylation);GO:0004721(phosphoprotein phosphatase activity);GO:0006470(protein dephosphorylation);GO:0003674(molecular_function);GO:0008150(biological_process);GO:0070062(extracellular exosome);GO:0001933(negative regulation of protein phosphorylation);GO:2000134(negative regulation of G1/S transition of mitotic cell cycle);GO:2000134(negative regulation of G1/S transition of mitotic cell cycle)","NA","NA","NA","CTD small phosphatase like [Source:HGNC Symbol;Acc:HGNC:16890]",{"v":0.386873965148378,"d":"0.39"},{"v":2.71160271014493,"d":"2.71"},{"v":0.142673542735802,"d":"0.14"},{"v":-2.80921026745084,"d":"-2.81"},{"v":8.70803337669857e-05,"d":"0.00"},{"v":0.0151974112930731,"d":"0.02"},"down","yes"]
["MSTRG.14524","NOV","ENST00000259526","GO:0005737(cytoplasm);GO:0043231(intracellular membrane-bounded organelle);GO:0008083(growth factor activity);GO:0005576(extracellular region);GO:0005520(insulin-like growth factor binding);GO:0001558(regulation of cell growth);GO:0005921(gap junction);GO:0030054(cell junction);GO:0002062(chondrocyte differentiation);GO:0010468(regulation of gene expression);GO:0044342(type B pancreatic cell proliferation);GO:0046676(negative regulation of insulin secretion);GO:0048659(smooth muscle cell proliferation);GO:0050728(negative regulation of inflammatory response);GO:0060392(negative regulation of SMAD protein import into nucleus);GO:1904057(negative regulation of sensory perception of pain);GO:1990523(bone regeneration);GO:0005615(extracellular space);GO:0030424(axon);GO:0030425(dendrite);GO:0031012(extracellular matrix);GO:0043025(neuronal cell body);GO:0005515(protein binding);GO:0007267(cell-cell signaling);GO:0005578(proteinaceous extracellular matrix);GO:0030308(negative regulation of cell growth);GO:0005178(integrin binding);GO:0001525(angiogenesis);GO:0005112(Notch binding);GO:0045747(positive regulation of Notch signaling pathway);GO:0060326(cell chemotaxis);GO:0008201(heparin binding);GO:0060548(negative regulation of cell death);GO:0042347(negative regulation of NF-kappaB import into nucleus);GO:0035767(endothelial cell chemotaxis);GO:0033627(cell adhesion mediated by integrin);GO:0010832(negative regulation of myotube differentiation);GO:0071603(endothelial cell-cell adhesion);GO:0010761(fibroblast migration);GO:0014909(smooth muscle cell migration);GO:0061484(hematopoietic stem cell homeostasis);GO:0090027(negative regulation of monocyte chemotaxis);GO:1902731(negative regulation of chondrocyte proliferation)","NA","NA","NA","nephroblastoma overexpressed [Source:HGNC Symbol;Acc:HGNC:7885]",{"v":1.15810372091283,"d":"1.16"},{"v":7.95006861503928,"d":"7.95"},{"v":0.145672166743571,"d":"0.15"},{"v":-2.77920284368214,"d":"-2.78"},{"v":8.96401317585631e-05,"d":"0.00"},{"v":0.0154206638090945,"d":"0.02"},"down","yes"]
["ENSG00000151835","SACS","ENST00000382292;ENST00000402364","GO:0005737(cytoplasm);GO:0005634(nucleus);GO:0006457(protein folding);GO:0051087(chaperone binding);GO:0030424(axon);GO:0030544(Hsp70 protein binding);GO:0005739(mitochondrion);GO:0030425(dendrite);GO:0090084(negative regulation of inclusion body assembly);GO:0070852(cell body fiber);GO:0070628(proteasome binding);GO:0070628(proteasome binding)","NA","NA","NA","sacsin molecular chaperone [Source:HGNC Symbol;Acc:HGNC:10519]",{"v":0.108105629424992,"d":"0.11"},{"v":0.759132050240925,"d":"0.76"},{"v":0.142406883480526,"d":"0.14"},{"v":-2.8119092117628,"d":"-2.81"},{"v":9.24023002093687e-05,"d":"0.00"},{"v":0.0156719506918481,"d":"0.02"},"down","yes"]
["ENSG00000105967","TFEC","ENST00000265440;ENST00000393485;ENST00000484212;ENST00000320239;ENST00000474337;ENST00000457268","GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0046983(protein dimerization activity);GO:0006355(regulation of transcription, DNA-templated);GO:0006366(transcription from RNA polymerase II promoter);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0005515(protein binding);GO:1903507(negative regulation of nucleic acid-templated transcription);GO:0003713(transcription coactivator activity);GO:0003714(transcription corepressor activity);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:0001077(transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0034605(cellular response to heat);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0045944(positive regulation of transcription from RNA polymerase II promoter)","NA","NA","NA","transcription factor EC [Source:HGNC Symbol;Acc:HGNC:11754]",{"v":0.39104452915317,"d":"0.39"},{"v":2.66836307022212,"d":"2.67"},{"v":0.146548471426948,"d":"0.15"},{"v":-2.77055017480438,"d":"-2.77"},{"v":9.75612349370918e-05,"d":"0.00"},{"v":0.0163171165432286,"d":"0.02"},"down","yes"]
["MSTRG.7179","CD300E","ENST00000392619;ENST00000412268","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005886(plasma membrane);GO:0002376(immune system process);GO:0050776(regulation of immune response);GO:0070062(extracellular exosome);GO:0045087(innate immune response);GO:0045087(innate immune response)","NA","NA","NA","CD300e molecule [Source:HGNC Symbol;Acc:HGNC:28874]",{"v":14.4396716993603,"d":"14.44"},{"v":2.24793838512793,"d":"2.25"},{"v":6.4235175638671,"d":"6.42"},{"v":2.68336354379661,"d":"2.68"},{"v":1.05300260163296E-4,"d":"0.00"},{"v":0.0171797765262547,"d":"0.02"},"up","yes"]
["ENSG00000138411","HECW2","ENST00000260983;ENST00000498146","GO:0005737(cytoplasm);GO:0016740(transferase activity);GO:0016567(protein ubiquitination);GO:0004842(ubiquitin-protein transferase activity);GO:0005856(cytoskeleton);GO:0005819(spindle);GO:0061630(ubiquitin protein ligase activity);GO:0043161(proteasome-mediated ubiquitin-dependent protein catabolic process);GO:0005515(protein binding);GO:0042787(protein ubiquitination involved in ubiquitin-dependent protein catabolic process);GO:0072686(mitotic spindle);GO:0030071(regulation of mitotic metaphase/anaphase transition);GO:0030071(regulation of mitotic metaphase/anaphase transition)","NA","NA","NA","HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2 [Source:HGNC Symbol;Acc:HGNC:29853]",{"v":0.0943436008509297,"d":"0.09"},{"v":0.657735581783801,"d":"0.66"},{"v":0.143436972947498,"d":"0.14"},{"v":-2.80151114746717,"d":"-2.80"},{"v":1.05986222819254E-4,"d":"0.00"},{"v":0.0171797765262547,"d":"0.02"},"down","yes"]
["ENSG00000182986","ZNF320","ENST00000597111;ENST00000594741;ENST00000391781;ENST00000596215;ENST00000600930;ENST00000597091;ENST00000601334;ENST00000595635;ENST00000597265;ENST00000597856","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0005622(intracellular);GO:0005515(protein binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding)","NA","NA","NA","zinc finger protein 320 [Source:HGNC Symbol;Acc:HGNC:13842]",{"v":1.12225429869664,"d":"1.12"},{"v":0.16821330479493,"d":"0.17"},{"v":6.67161435336395,"d":"6.67"},{"v":2.7380358975102,"d":"2.74"},{"v":0.00010978391472129,"d":"0.00"},{"v":0.0171797765262547,"d":"0.02"},"up","yes"]
["MSTRG.2431","TMEM109","ENST00000227525;ENST00000536171;ENST00000540280","GO:0006810(transport);GO:0005634(nucleus);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005244(voltage-gated ion channel activity);GO:0006811(ion transport);GO:0034765(regulation of ion transmembrane transport);GO:0003674(molecular_function);GO:0070062(extracellular exosome);GO:0016529(sarcoplasmic reticulum);GO:0033017(sarcoplasmic reticulum membrane);GO:0060548(negative regulation of cell death);GO:0071480(cellular response to gamma radiation);GO:0005640(nuclear outer membrane);GO:0042771(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator);GO:0042771(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)","NA","NA","NA","transmembrane protein 109 [Source:HGNC Symbol;Acc:HGNC:28771]",{"v":20.9785947666254,"d":"20.98"},{"v":3.28632498389095,"d":"3.29"},{"v":6.38360322532287,"d":"6.38"},{"v":2.67437098322563,"d":"2.67"},{"v":0.000109852826064719,"d":"0.00"},{"v":0.0171797765262547,"d":"0.02"},"up","yes"]
["MSTRG.11150","ZNF148","ENST00000360647;ENST00000492394;ENST00000485866;ENST00000497929;ENST00000495019;ENST00000484491;ENST00000471196","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0005794(Golgi apparatus);GO:0046872(metal ion binding);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:0001078(transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0021762(substantia nigra development);GO:0043565(sequence-specific DNA binding);GO:0010629(negative regulation of gene expression);GO:0045892(negative regulation of transcription, DNA-templated);GO:0006366(transcription from RNA polymerase II promoter);GO:0006968(cellular defense response);GO:0000976(transcription regulatory region sequence-specific DNA binding);GO:0003690(double-stranded DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0006461(protein complex assembly);GO:0007276(gamete generation);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0045944(positive regulation of transcription from RNA polymerase II promoter)","NA","NA","NA","zinc finger protein 148 [Source:HGNC Symbol;Acc:HGNC:12933]",{"v":0.456280681482883,"d":"0.46"},{"v":3.04973347787025,"d":"3.05"},{"v":0.149613297290989,"d":"0.15"},{"v":-2.74068969049584,"d":"-2.74"},{"v":1.10072078871728E-4,"d":"0.00"},{"v":0.0171797765262547,"d":"0.02"},"down","yes"]
["ENSG00000235437","LINC01278","ENST00000609143;ENST00000608623;ENST00000433061;ENST00000609401;ENST00000608788","NA","NA","NA","NA","long intergenic non-protein coding RNA 1278 [Source:HGNC Symbol;Acc:HGNC:28090]",{"v":2.97989702915818,"d":"2.98"},{"v":0.460003305533783,"d":"0.46"},{"v":6.47799046943878,"d":"6.48"},{"v":2.69554634561017,"d":"2.70"},{"v":1.12430225523926E-4,"d":"0.00"},{"v":0.0171797765262547,"d":"0.02"},"up","yes"]
["ENSG00000133393","FOPNL","ENST00000255759;ENST00000575938;ENST00000575073;ENST00000572415;ENST00000573087;ENST00000575744;ENST00000573396;ENST00000573968","GO:0005737(cytoplasm);GO:0005634(nucleus);GO:0031514(motile cilium);GO:0005813(centrosome);GO:0005856(cytoskeleton);GO:0042995(cell projection);GO:0005815(microtubule organizing center);GO:0034453(microtubule anchoring);GO:0060271(cilium assembly);GO:0005929(cilium);GO:0030030(cell projection organization);GO:0005814(centriole);GO:0036064(ciliary basal body);GO:0034451(centriolar satellite);GO:0034451(centriolar satellite)","NA","NA","NA","FGFR1OP N-terminal like [Source:HGNC Symbol;Acc:HGNC:26435]",{"v":0.531576723128398,"d":"0.53"},{"v":3.6606211229611,"d":"3.66"},{"v":0.145214898038506,"d":"0.15"},{"v":-2.78373862348413,"d":"-2.78"},{"v":1.12705725425521E-4,"d":"0.00"},{"v":0.0171797765262547,"d":"0.02"},"down","yes"]
["ENSG00000167384","ZNF180","ENST00000221327;ENST00000585514;ENST00000592529;ENST00000586637;ENST00000592095;ENST00000590088;ENST00000591064","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0005622(intracellular);GO:0005515(protein binding);GO:0005515(protein binding)","NA","NA","NA","zinc finger protein 180 [Source:HGNC Symbol;Acc:HGNC:12970]",{"v":1.01700722057286,"d":"1.02"},{"v":0.145759501568054,"d":"0.15"},{"v":6.9772962285963,"d":"6.98"},{"v":2.80266808610806,"d":"2.80"},{"v":1.17793814242892E-4,"d":"0.00"},{"v":0.0177309138889113,"d":"0.02"},"up","yes"]
["MSTRG.15084","FCN1","MSTRG.15084.1","NA","NA","NA","NA",null,{"v":1.582985,"d":"1.58"},{"v":0.23546,"d":"0.24"},{"v":6.72294657266627,"d":"6.72"},{"v":2.74909368450094,"d":"2.75"},{"v":1.2235187338735E-4,"d":"0.00"},{"v":0.0181896451769194,"d":"0.02"},"up","yes"]
["ENSG00000126705","AHDC1","ENST00000490295;ENST00000374011;ENST00000247087;ENST00000480033;ENST00000487743","GO:0003677(DNA binding);GO:0003677(DNA binding)","NA","NA","NA","AT-hook DNA binding motif containing 1 [Source:HGNC Symbol;Acc:HGNC:25230]",{"v":2.04143628196172,"d":"2.04"},{"v":0.32253358474221,"d":"0.32"},{"v":6.32937584962933,"d":"6.33"},{"v":2.66206324008949,"d":"2.66"},{"v":1.37272273288939E-4,"d":"0.00"},{"v":0.0200882404175705,"d":"0.02"},"up","yes"]
["MSTRG.5712","GDE1","ENST00000353258;ENST00000563645;ENST00000569773;ENST00000569899;ENST00000564172","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0046872(metal ion binding);GO:0016787(hydrolase activity);GO:0006629(lipid metabolic process);GO:0005886(plasma membrane);GO:0030659(cytoplasmic vesicle membrane);GO:0031410(cytoplasmic vesicle);GO:0008081(phosphoric diester hydrolase activity);GO:0008889(glycerophosphodiester phosphodiesterase activity);GO:0046475(glycerophospholipid catabolic process);GO:0004622(lysophospholipase activity);GO:0047395(glycerophosphoinositol glycerophosphodiesterase activity);GO:0006644(phospholipid metabolic process);GO:0070291(N-acylethanolamine metabolic process);GO:0070291(N-acylethanolamine metabolic process)","NA","NA","NA","glycerophosphodiester phosphodiesterase 1 [Source:HGNC Symbol;Acc:HGNC:29644]",{"v":1.61327324501812,"d":"1.61"},{"v":10.3864587259964,"d":"10.39"},{"v":0.155324667201559,"d":"0.16"},{"v":-2.68664113172109,"d":"-2.69"},{"v":1.38459056191526E-4,"d":"0.00"},{"v":0.0200882404175705,"d":"0.02"},"down","yes"]
["ENSG00000172315","TP53RK","ENST00000372114;ENST00000372102","GO:0005634(nucleus);GO:0016020(membrane);GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0016740(transferase activity);GO:0008033(tRNA processing);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0016787(hydrolase activity);GO:0016773(phosphotransferase activity, alcohol group as acceptor);GO:0005515(protein binding);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:1901796(regulation of signal transduction by p53 class mediator);GO:0000408(EKC/KEOPS complex);GO:0002039(p53 binding);GO:0070525(tRNA threonylcarbamoyladenosine metabolic process);GO:0070525(tRNA threonylcarbamoyladenosine metabolic process)","NA","NA","NA","TP53 regulating kinase [Source:HGNC Symbol;Acc:HGNC:16197]",{"v":3.63390116107955,"d":"3.63"},{"v":0.576921453409091,"d":"0.58"},{"v":6.29877973787668,"d":"6.30"},{"v":2.65507236248075,"d":"2.66"},{"v":0.000144172124904769,"d":"0.00"},{"v":0.0206681039059909,"d":"0.02"},"up","yes"]
["MSTRG.12816","ZNRD1ASP","ENST00000437417;ENST00000431012;ENST00000376797;ENST00000421692;ENST00000448093;ENST00000420251;ENST00000444051;ENST00000452229;ENST00000425604","NA","NA","NA","NA","zinc ribbon domain containing 1 antisense, pseudogene [Source:HGNC Symbol;Acc:HGNC:13924]",{"v":0.284373435283385,"d":"0.28"},{"v":0.0427786461398107,"d":"0.04"},{"v":6.64755575372782,"d":"6.65"},{"v":2.73282397216408,"d":"2.73"},{"v":0.000154801608185721,"d":"0.00"},{"v":0.0219308348914406,"d":"0.02"},"up","yes"]
["ENSG00000127125","PPCS","ENST00000372561;ENST00000372556;ENST00000372562;ENST00000471420;ENST00000482168;ENST00000372560;ENST00000472013;ENST00000469615","GO:0016874(ligase activity);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0009108(coenzyme biosynthetic process);GO:0015937(coenzyme A biosynthetic process);GO:0004632(phosphopantothenate--cysteine ligase activity);GO:0004632(phosphopantothenate--cysteine ligase activity)","00770(Pantothenate and CoA biosynthesis);00770(Pantothenate and CoA biosynthesis)","K01922","EC:6.3.2.51","phosphopantothenoylcysteine synthetase [Source:HGNC Symbol;Acc:HGNC:25686]",{"v":1.61718407528957,"d":"1.62"},{"v":10.3604258046332,"d":"10.36"},{"v":0.156092433437085,"d":"0.16"},{"v":-2.67952749035419,"d":"-2.68"},{"v":1.58964188115725E-4,"d":"0.00"},{"v":0.0222586831777856,"d":"0.02"},"down","yes"]
["MSTRG.7821","RAB3D;TMEM205;AC011472.2","MSTRG.7821.2;MSTRG.7821.1;ENST00000593256;ENST00000586356;ENST00000586590;ENST00000589555;ENST00000588321;ENST00000587948;ENST00000591677;ENST00000588560;ENST00000586956;ENST00000590482;ENST00000590788;ENST00000222120;ENST00000589655;ENST00000354882;ENST00000585722;ENST00000592952;ENST00000447337","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0070062(extracellular exosome);GO:0006810(transport);GO:0015031(protein transport);GO:0005525(GTP binding);GO:0000166(nucleotide binding);GO:0003924(GTPase activity);GO:0005886(plasma membrane);GO:0030742(GTP-dependent protein binding);GO:0017157(regulation of exocytosis);GO:0018125(peptidyl-cysteine methylation);GO:0005739(mitochondrion);GO:0030133(transport vesicle);GO:0042588(zymogen granule);GO:0006887(exocytosis);GO:0043312(neutrophil degranulation);GO:0031489(myosin V binding);GO:0035577(azurophil granule membrane);GO:0045453(bone resorption);GO:1903307(positive regulation of regulated secretory pathway);GO:0005881(cytoplasmic microtubule);GO:0099503(secretory vesicle);GO:0070062(extracellular exosome)","04972(Pancreatic secretion);04972(Pancreatic secretion)","K07884","NA","transmembrane protein 205 [Source:HGNC Symbol;Acc:HGNC:29631];RAB3D, member RAS oncogene family [Source:HGNC Symbol;Acc:HGNC:9779]",{"v":3.47898383046875,"d":"3.48"},{"v":21.6966816736979,"d":"21.70"},{"v":0.16034635539158,"d":"0.16"},{"v":-2.64073653261544,"d":"-2.64"},{"v":1.66630756076458E-4,"d":"0.00"},{"v":0.0229061119896097,"d":"0.02"},"down","yes"]
["MSTRG.14161","PTPRN2","ENST00000389413;ENST00000404321","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016787(hydrolase activity);GO:0006629(lipid metabolic process);GO:0004725(protein tyrosine phosphatase activity);GO:0016791(phosphatase activity);GO:0006470(protein dephosphorylation);GO:0016311(dephosphorylation);GO:0035335(peptidyl-tyrosine dephosphorylation);GO:0004721(phosphoprotein phosphatase activity);GO:0030054(cell junction);GO:0045202(synapse);GO:0031410(cytoplasmic vesicle);GO:0005886(plasma membrane);GO:0005887(integral component of plasma membrane);GO:0043312(neutrophil degranulation);GO:0030672(synaptic vesicle membrane);GO:0007269(neurotransmitter secretion);GO:0043235(receptor complex);GO:0101003(ficolin-1-rich granule membrane);GO:0030658(transport vesicle membrane);GO:0005001(transmembrane receptor protein tyrosine phosphatase activity);GO:0030667(secretory granule membrane);GO:0035773(insulin secretion involved in cellular response to glucose stimulus);GO:0034260(negative regulation of GTPase activity);GO:0005737(cytoplasm);GO:0005788(endoplasmic reticulum lumen);GO:0030141(secretory granule);GO:0043195(terminal bouton);GO:0043195(terminal bouton)","04940(Type I diabetes mellitus);04940(Type I diabetes mellitus)","K07817","EC:3.1.3.48","protein tyrosine phosphatase, receptor type N2 [Source:HGNC Symbol;Acc:HGNC:9677]",{"v":0.139111064142355,"d":"0.14"},{"v":0.94783485888682,"d":"0.95"},{"v":0.146767195612254,"d":"0.15"},{"v":-2.7683985518847,"d":"-2.77"},{"v":1.67392281604854E-4,"d":"0.00"},{"v":0.0229061119896097,"d":"0.02"},"down","yes"]
["MSTRG.11423","IL1RAP","ENST00000413869;ENST00000342550;ENST00000422940;ENST00000412504;ENST00000465496;ENST00000439062;ENST00000482913;ENST00000422625;ENST00000461629;ENST00000473566;ENST00000447382;ENST00000412080;ENST00000422485;ENST00000072516;ENST00000317757","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0007165(signal transduction);GO:0005886(plasma membrane);GO:0005576(extracellular region);GO:0002376(immune system process);GO:0045087(innate immune response);GO:0006954(inflammatory response);GO:0005887(integral component of plasma membrane);GO:0004908(interleukin-1 receptor activity);GO:0004871(signal transducer activity);GO:0006955(immune response);GO:0006461(protein complex assembly);GO:0051965(positive regulation of synapse assembly);GO:0019221(cytokine-mediated signaling pathway);GO:0002114(interleukin-33 receptor activity);GO:1990782(protein tyrosine kinase binding);GO:0032736(positive regulation of interleukin-13 production);GO:0032754(positive regulation of interleukin-5 production);GO:0038172(interleukin-33-mediated signaling pathway);GO:0042094(interleukin-2 biosynthetic process);GO:0051092(positive regulation of NF-kappaB transcription factor activity);GO:0072602(interleukin-4 secretion);GO:1900006(positive regulation of dendrite development);GO:2000778(positive regulation of interleukin-6 secretion);GO:0005615(extracellular space);GO:0005615(extracellular space)","04010(MAPK signaling pathway);04060(Cytokine-cytokine receptor interaction);04659(Th17 cell differentiation);04750(Inflammatory mediator regulation of TRP channels);04750(Inflammatory mediator regulation of TRP channels)","K04723","NA","interleukin 1 receptor accessory protein [Source:HGNC Symbol;Acc:HGNC:5995]",{"v":1.30570719274215,"d":"1.31"},{"v":8.12499524077204,"d":"8.12"},{"v":0.160702517853793,"d":"0.16"},{"v":-2.63753556184994,"d":"-2.64"},{"v":1.70913209958343E-4,"d":"0.00"},{"v":0.0229169969206075,"d":"0.02"},"down","yes"]
["ENSG00000171659","GPR34","ENST00000378142;ENST00000378138","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0004930(G-protein coupled receptor activity);GO:0007186(G-protein coupled receptor signaling pathway);GO:0005886(plasma membrane);GO:0004871(signal transducer activity);GO:0007165(signal transduction);GO:0035589(G-protein coupled purinergic nucleotide receptor signaling pathway);GO:0005887(integral component of plasma membrane);GO:0045028(G-protein coupled purinergic nucleotide receptor activity);GO:0045028(G-protein coupled purinergic nucleotide receptor activity)","NA","NA","NA","G protein-coupled receptor 34 [Source:HGNC Symbol;Acc:HGNC:4490]",{"v":0.400844105290456,"d":"0.40"},{"v":2.710139,"d":"2.71"},{"v":0.147905367691641,"d":"0.15"},{"v":-2.75725368408939,"d":"-2.76"},{"v":0.000173008720342629,"d":"0.00"},{"v":0.0229169969206075,"d":"0.02"},"down","yes"]
["ENSG00000196268","ZNF493","ENST00000599461;ENST00000392288;ENST00000355504;ENST00000596302;ENST00000594390;ENST00000339914;ENST00000599517;ENST00000598152","GO:0003676(nucleic acid binding);GO:0006355(regulation of transcription, DNA-templated);GO:0005622(intracellular);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding)","NA","NA","NA","zinc finger protein 493 [Source:HGNC Symbol;Acc:HGNC:23708]",{"v":0.129859757178527,"d":"0.13"},{"v":0.84222909827002,"d":"0.84"},{"v":0.154185787982469,"d":"0.15"},{"v":-2.69725830338371,"d":"-2.70"},{"v":0.000173181092823059,"d":"0.00"},{"v":0.0229169969206075,"d":"0.02"},"down","yes"]
["ENSG00000154188","ANGPT1","ENST00000297450;ENST00000517746;ENST00000521950;ENST00000518386;ENST00000522400","GO:0005622(intracellular);GO:0005886(plasma membrane);GO:0043547(positive regulation of GTPase activity);GO:0005576(extracellular region);GO:0007275(multicellular organism development);GO:0005615(extracellular space);GO:0001525(angiogenesis);GO:0030154(cell differentiation);GO:0045121(membrane raft);GO:0050900(leukocyte migration);GO:0030971(receptor tyrosine kinase binding);GO:0002040(sprouting angiogenesis);GO:0070062(extracellular exosome);GO:0000165(MAPK cascade);GO:0031398(positive regulation of protein ubiquitination);GO:0005902(microvillus);GO:0048014(Tie signaling pathway);GO:0043066(negative regulation of apoptotic process);GO:0070374(positive regulation of ERK1 and ERK2 cascade);GO:0043116(negative regulation of vascular permeability);GO:0005088(Ras guanyl-nucleotide exchange factor activity);GO:2000352(negative regulation of endothelial cell apoptotic process);GO:0007162(negative regulation of cell adhesion);GO:0034394(protein localization to cell surface);GO:0010595(positive regulation of endothelial cell migration);GO:0051897(positive regulation of protein kinase B signaling);GO:0072012(glomerulus vasculature development);GO:0050731(positive regulation of peptidyl-tyrosine phosphorylation);GO:0050918(positive chemotaxis);GO:0030210(heparin biosynthetic process);GO:0002092(positive regulation of receptor internalization);GO:0014842(regulation of skeletal muscle satellite cell proliferation);GO:0007171(activation of transmembrane receptor protein tyrosine kinase activity);GO:0005102(receptor binding);GO:0001701(in utero embryonic development);GO:0001933(negative regulation of protein phosphorylation);GO:0002740(negative regulation of cytokine secretion involved in immune response);GO:0007169(transmembrane receptor protein tyrosine kinase signaling pathway);GO:0014068(positive regulation of phosphatidylinositol 3-kinase signaling);GO:0030097(hemopoiesis);GO:0031589(cell-substrate adhesion);GO:0032680(regulation of tumor necrosis factor production);GO:0033138(positive regulation of peptidyl-serine phosphorylation);GO:0042308(negative regulation of protein import into nucleus);GO:0043122(regulation of I-kappaB kinase/NF-kappaB signaling);GO:0043393(regulation of protein binding);GO:0043524(negative regulation of neuron apoptotic process);GO:0043536(positive regulation of blood vessel endothelial cell migration);GO:0045785(positive regulation of cell adhesion);GO:2000446(regulation of macrophage migration inhibitory factor signaling pathway);GO:2000446(regulation of macrophage migration inhibitory factor signaling pathway)","04014(Ras signaling pathway);04015(Rap1 signaling pathway);04010(MAPK signaling pathway);04066(HIF-1 signaling pathway);04151(PI3K-Akt signaling pathway);05323(Rheumatoid arthritis);05323(Rheumatoid arthritis)","K05465","NA","angiopoietin 1 [Source:HGNC Symbol;Acc:HGNC:484]",{"v":0.23090944640853,"d":"0.23"},{"v":1.47651464323793,"d":"1.48"},{"v":0.156388185830759,"d":"0.16"},{"v":-2.67679656489654,"d":"-2.68"},{"v":0.000176242253890421,"d":"0.00"},{"v":0.023068578492918,"d":"0.02"},"down","yes"]
["ENSG00000185670","ZBTB3","ENST00000530112;ENST00000394807","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0003677(DNA binding)","NA","NA","NA","zinc finger and BTB domain containing 3 [Source:HGNC Symbol;Acc:HGNC:22918]",{"v":0.204430142771804,"d":"0.20"},{"v":1.36485440262843,"d":"1.36"},{"v":0.149781648781081,"d":"0.15"},{"v":-2.73906721898343,"d":"-2.74"},{"v":0.000192183511978709,"d":"0.00"},{"v":0.0248846650671786,"d":"0.02"},"down","yes"]
["MSTRG.14100","TRBV20-1","ENST00000390394","NA","NA","NA","NA","T-cell receptor beta variable 20-1 [Source:HGNC Symbol;Acc:HGNC:12196]",{"v":14.451065,"d":"14.45"},{"v":2.366255,"d":"2.37"},{"v":6.10714610217411,"d":"6.11"},{"v":2.61049835940431,"d":"2.61"},{"v":0.000218437040682535,"d":"0.00"},{"v":0.0279831791904158,"d":"0.03"},"up","yes"]
["MSTRG.2532","AP003068.2","ENST00000526623;ENST00000528551","NA","NA","NA","NA",null,{"v":1.89653209045226,"d":"1.90"},{"v":11.5353660837521,"d":"11.54"},{"v":0.164410221286655,"d":"0.16"},{"v":-2.60462810157836,"d":"-2.60"},{"v":2.24200721935831E-4,"d":"0.00"},{"v":0.028262946199434,"d":"0.03"},"down","yes"]
["ENSG00000175040","CHST2","ENST00000309575","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005794(Golgi apparatus);GO:0016740(transferase activity);GO:0005975(carbohydrate metabolic process);GO:0008146(sulfotransferase activity);GO:0000139(Golgi membrane);GO:0006954(inflammatory response);GO:0005802(trans-Golgi network);GO:0007275(multicellular organism development);GO:0018146(keratan sulfate biosynthetic process);GO:0006790(sulfur compound metabolic process);GO:0006044(N-acetylglucosamine metabolic process);GO:0031228(intrinsic component of Golgi membrane);GO:0001517(N-acetylglucosamine 6-O-sulfotransferase activity)","00533(Glycosaminoglycan biosynthesis - keratan sulfate)","K04745","EC:2.8.2.-","carbohydrate sulfotransferase 2 [Source:HGNC Symbol;Acc:HGNC:1970]",{"v":0.77664,"d":"0.78"},{"v":4.708258,"d":"4.71"},{"v":0.164952727739219,"d":"0.16"},{"v":-2.59987545967439,"d":"-2.60"},{"v":0.000225314967210236,"d":"0.00"},{"v":0.028262946199434,"d":"0.03"},"down","yes"]
["MSTRG.102","KLHL21","ENST00000377658;ENST00000377663;ENST00000496707;ENST00000463043","GO:0005737(cytoplasm);GO:0016567(protein ubiquitination);GO:0051301(cell division);GO:0005856(cytoskeleton);GO:0007049(cell cycle);GO:0005819(spindle);GO:0005829(cytosol);GO:0043687(post-translational protein modification);GO:0004842(ubiquitin-protein transferase activity);GO:0031463(Cul3-RING ubiquitin ligase complex);GO:0032465(regulation of cytokinesis);GO:0005827(polar microtubule);GO:0035853(chromosome passenger complex localization to spindle midzone);GO:0035853(chromosome passenger complex localization to spindle midzone)","NA","NA","NA","kelch like family member 21 [Source:HGNC Symbol;Acc:HGNC:29041]",{"v":0.993710245471671,"d":"0.99"},{"v":5.96422341501232,"d":"5.96"},{"v":0.166611841362354,"d":"0.17"},{"v":-2.58543715596267,"d":"-2.59"},{"v":0.000229079516616787,"d":"0.00"},{"v":0.0284389230834984,"d":"0.03"},"down","yes"]
["MSTRG.10000","IFNAR1","ENST00000270139;ENST00000493503","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0005764(lysosome);GO:0019221(cytokine-mediated signaling pathway);GO:0005887(integral component of plasma membrane);GO:0005768(endosome);GO:0032496(response to lipopolysaccharide);GO:0005770(late endosome);GO:0004920(interleukin-10 receptor activity);GO:0009615(response to virus);GO:0007259(JAK-STAT cascade);GO:0060337(type I interferon signaling pathway);GO:0060338(regulation of type I interferon-mediated signaling pathway);GO:0035457(cellular response to interferon-alpha);GO:0004904(interferon receptor activity);GO:0004905(type I interferon receptor activity);GO:0019962(type I interferon binding);GO:0032728(positive regulation of interferon-beta production);GO:0032729(positive regulation of interferon-gamma production);GO:0042110(T cell activation);GO:0045351(type I interferon biosynthetic process);GO:0045893(positive regulation of transcription, DNA-templated);GO:0050718(positive regulation of interleukin-1 beta secretion);GO:0050730(regulation of peptidyl-tyrosine phosphorylation);GO:0051607(defense response to virus);GO:0060759(regulation of response to cytokine stimulus);GO:0060759(regulation of response to cytokine stimulus)","04630(Jak-STAT signaling pathway);04151(PI3K-Akt signaling pathway);04060(Cytokine-cytokine receptor interaction);04217(Necroptosis);04620(Toll-like receptor signaling pathway);04621(NOD-like receptor signaling pathway);04650(Natural killer cell mediated cytotoxicity);04380(Osteoclast differentiation);05200(Pathways in cancer);05162(Measles);05164(Influenza A);05161(Hepatitis B);05160(Hepatitis C);05168(Herpes simplex infection);05167(Kaposi's sarcoma-associated herpesvirus infection);05165(Human papillomavirus infection);05165(Human papillomavirus infection)","K05130","NA","interferon alpha and beta receptor subunit 1 [Source:HGNC Symbol;Acc:HGNC:5432]",{"v":2.00945559673068,"d":"2.01"},{"v":11.9628453332804,"d":"11.96"},{"v":0.167974720122847,"d":"0.17"},{"v":-2.57368396841717,"d":"-2.57"},{"v":0.000235293646603405,"d":"0.00"},{"v":0.0285615076055519,"d":"0.03"},"down","yes"]
["MSTRG.14127","GIMAP2","ENST00000223293;ENST00000474605;ENST00000487388","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005525(GTP binding);GO:0000166(nucleotide binding);GO:0005811(lipid particle);GO:0005811(lipid particle)","NA","NA","NA","GTPase, IMAP family member 2 [Source:HGNC Symbol;Acc:HGNC:21789]",{"v":10.2347451177873,"d":"10.23"},{"v":1.75640145445875,"d":"1.76"},{"v":5.82711036352519,"d":"5.83"},{"v":2.54278063510649,"d":"2.54"},{"v":0.000236800982430345,"d":"0.00"},{"v":0.0285615076055519,"d":"0.03"},"up","yes"]
["MSTRG.12840","HCP5;MICA","ENST00000541196;ENST00000616296;ENST00000449934;ENST00000467369;ENST00000460889;ENST00000421350","NA","04650(Natural killer cell mediated cytotoxicity);05167(Kaposi's sarcoma-associated herpesvirus infection);05167(Kaposi's sarcoma-associated herpesvirus infection)","K07985","NA","HLA complex P5 (non-protein coding) [Source:HGNC Symbol;Acc:HGNC:21659];MHC class I polypeptide-related sequence A [Source:HGNC Symbol;Acc:HGNC:7090]",{"v":14.9407673628707,"d":"14.94"},{"v":2.60840858641523,"d":"2.61"},{"v":5.72792446731054,"d":"5.73"},{"v":2.51801246827344,"d":"2.52"},{"v":2.38875270262205E-4,"d":"0.00"},{"v":0.0285615076055519,"d":"0.03"},"up","yes"]
["MSTRG.14598","SLC45A4","MSTRG.14598.2;ENST00000519067;ENST00000024061;ENST00000521804;ENST00000517878;ENST00000520137;ENST00000519986","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0008506(sucrose:proton symporter activity);GO:0015770(sucrose transport);GO:0015770(sucrose transport)","NA","NA","NA","solute carrier family 45 member 4 [Source:HGNC Symbol;Acc:HGNC:29196]",{"v":1.39934295773196,"d":"1.40"},{"v":8.32422720927835,"d":"8.32"},{"v":0.168104848960901,"d":"0.17"},{"v":-2.57256675537603,"d":"-2.57"},{"v":0.0002395542491414,"d":"0.00"},{"v":0.0285615076055519,"d":"0.03"},"down","yes"]
["ENSG00000148773","MKI67","ENST00000368654;ENST00000484853;ENST00000368653;ENST00000478293","GO:0003723(RNA binding);GO:0005634(nucleus);GO:0016020(membrane);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0005730(nucleolus);GO:0003677(DNA binding);GO:0005694(chromosome);GO:0005515(protein binding);GO:0007049(cell cycle);GO:0016604(nuclear body);GO:0008283(cell proliferation);GO:0008022(protein C-terminus binding);GO:0007088(regulation of mitotic nuclear division);GO:0051983(regulation of chromosome segregation);GO:0000793(condensed chromosome);GO:1902275(regulation of chromatin organization);GO:0006259(DNA metabolic process);GO:0014070(response to organic cyclic compound);GO:0030212(hyaluronan metabolic process);GO:0031100(animal organ regeneration);GO:0034605(cellular response to heat);GO:0051321(meiotic cell cycle);GO:0000775(chromosome, centromeric region);GO:0005737(cytoplasm);GO:0005737(cytoplasm)","NA","NA","NA","marker of proliferation Ki-67 [Source:HGNC Symbol;Acc:HGNC:7107]",{"v":1.86246211759194,"d":"1.86"},{"v":0.322754149059108,"d":"0.32"},{"v":5.77052881588474,"d":"5.77"},{"v":2.52870353465864,"d":"2.53"},{"v":0.000251371400891197,"d":"0.00"},{"v":0.0296766118581548,"d":"0.03"},"up","yes"]
["MSTRG.15121","FUT7;NPDC1","ENST00000314412;ENST00000371600;ENST00000371601;ENST00000488145;ENST00000496498;ENST00000485589","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005794(Golgi apparatus);GO:0016740(transferase activity);GO:0016757(transferase activity, transferring glycosyl groups);GO:0006486(protein glycosylation);GO:0032580(Golgi cisterna membrane);GO:0036065(fucosylation);GO:0008417(fucosyltransferase activity);GO:0000139(Golgi membrane);GO:0042355(L-fucose catabolic process);GO:0006672(ceramide metabolic process);GO:0046920(alpha-(1->3)-fucosyltransferase activity);GO:0002361(CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation);GO:0002522(leukocyte migration involved in immune response);GO:0005515(protein binding);GO:0050776(regulation of immune response);GO:0005886(plasma membrane);GO:0005886(plasma membrane)","00601(Glycosphingolipid biosynthesis - lacto and neolacto series)","K07635","EC:2.4.1.-","fucosyltransferase 7 [Source:HGNC Symbol;Acc:HGNC:4018];neural proliferation, differentiation and control 1 [Source:HGNC Symbol;Acc:HGNC:7899]",{"v":0.90788456192445,"d":"0.91"},{"v":5.37870877429055,"d":"5.38"},{"v":0.16879228826517,"d":"0.17"},{"v":-2.56667910278388,"d":"-2.57"},{"v":0.000261192997181448,"d":"0.00"},{"v":0.0305367579811553,"d":"0.03"},"down","yes"]
["MSTRG.1175","MPZL1","ENST00000474859;ENST00000392121;ENST00000465787;ENST00000403379;ENST00000464954;ENST00000359523;ENST00000367853;ENST00000474729;ENST00000487858;ENST00000498279","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0007165(signal transduction);GO:0005887(integral component of plasma membrane);GO:0005515(protein binding);GO:0005925(focal adhesion);GO:0007267(cell-cell signaling);GO:0009986(cell surface);GO:0007169(transmembrane receptor protein tyrosine kinase signaling pathway);GO:0005198(structural molecule activity);GO:0005198(structural molecule activity)","04514(Cell adhesion molecules (CAMs));04514(Cell adhesion molecules (CAMs))","K06770","NA","myelin protein zero like 1 [Source:HGNC Symbol;Acc:HGNC:7226]",{"v":0.578924862215306,"d":"0.58"},{"v":3.45556551251945,"d":"3.46"},{"v":0.167534043304308,"d":"0.17"},{"v":-2.57747381056524,"d":"-2.58"},{"v":2.65346326732722E-4,"d":"0.00"},{"v":0.0306869855821366,"d":"0.03"},"down","yes"]
["MSTRG.14030","MGAM","ENST00000475668;MSTRG.14030.3;ENST00000620571;ENST00000497673;ENST00000495045;ENST00000490593;ENST00000549489;MSTRG.14030.4;ENST00000485078","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0030246(carbohydrate binding);GO:0016787(hydrolase activity);GO:0003824(catalytic activity);GO:0005975(carbohydrate metabolic process);GO:0005886(plasma membrane);GO:0008152(metabolic process);GO:0004553(hydrolase activity, hydrolyzing O-glycosyl compounds);GO:0016798(hydrolase activity, acting on glycosyl bonds);GO:0070062(extracellular exosome);GO:0043312(neutrophil degranulation);GO:0070821(tertiary granule membrane);GO:0016324(apical plasma membrane);GO:0101003(ficolin-1-rich granule membrane);GO:0004339(glucan 1,4-alpha-glucosidase activity);GO:0004558(alpha-1,4-glucosidase activity);GO:0016160(amylase activity);GO:0032450(maltose alpha-glucosidase activity);GO:0000023(maltose metabolic process);GO:0005983(starch catabolic process);GO:0044245(polysaccharide digestion);GO:0044245(polysaccharide digestion)","00052(Galactose metabolism);00500(Starch and sucrose metabolism);04973(Carbohydrate digestion and absorption);04973(Carbohydrate digestion and absorption)","K12047","EC:3.2.1.20;EC:3.2.1.3","maltase-glucoamylase [Source:HGNC Symbol;Acc:HGNC:7043]",{"v":3.90079763784231,"d":"3.90"},{"v":22.7541202809226,"d":"22.75"},{"v":0.171432584063151,"d":"0.17"},{"v":-2.54428674740564,"d":"-2.54"},{"v":0.000268716522549138,"d":"0.00"},{"v":0.0306869855821366,"d":"0.03"},"down","yes"]
["MSTRG.6311","EMC6","ENST00000397133;ENST00000248378","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005783(endoplasmic reticulum);GO:0005515(protein binding);GO:0000045(autophagosome assembly);GO:0072546(ER membrane protein complex);GO:0030176(integral component of endoplasmic reticulum membrane);GO:0034975(protein folding in endoplasmic reticulum);GO:0097631(integral component of omegasome membrane);GO:0097631(integral component of omegasome membrane)","NA","NA","NA","ER membrane protein complex subunit 6 [Source:HGNC Symbol;Acc:HGNC:28430]",{"v":0.81092121846554,"d":"0.81"},{"v":5.32304662158648,"d":"5.32"},{"v":0.152341558530978,"d":"0.15"},{"v":-2.71461853449475,"d":"-2.71"},{"v":0.000270122942344003,"d":"0.00"},{"v":0.0306869855821366,"d":"0.03"},"down","yes"]
["MSTRG.1108","TAGLN2","ENST00000368097;ENST00000478033;ENST00000368096;ENST00000320307;ENST00000397334","GO:0005515(protein binding);GO:0005576(extracellular region);GO:0005829(cytosol);GO:0045296(cadherin binding);GO:0070062(extracellular exosome);GO:0002576(platelet degranulation);GO:0031982(vesicle);GO:0030855(epithelial cell differentiation);GO:0030855(epithelial cell differentiation)","NA","NA","NA","transgelin 2 [Source:HGNC Symbol;Acc:HGNC:11554]",{"v":75.2462200912746,"d":"75.25"},{"v":436.332509029353,"d":"436.33"},{"v":0.172451555944489,"d":"0.17"},{"v":-2.53573694931115,"d":"-2.54"},{"v":0.000277958852905133,"d":"0.00"},{"v":0.0312820608101272,"d":"0.03"},"down","yes"]
["MSTRG.14958","ARPC5L","ENST00000259477;ENST00000465124;ENST00000353214","GO:0005737(cytoplasm);GO:0003779(actin binding);GO:0015629(actin cytoskeleton);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0030833(regulation of actin filament polymerization);GO:0034314(Arp2/3 complex-mediated actin nucleation);GO:0005885(Arp2/3 protein complex);GO:0005925(focal adhesion);GO:0003674(molecular_function);GO:0008150(biological_process);GO:0070062(extracellular exosome);GO:0051015(actin filament binding);GO:0016477(cell migration);GO:0016477(cell migration)","04144(Endocytosis);04810(Regulation of actin cytoskeleton);04666(Fc gamma R-mediated phagocytosis);05130(Pathogenic Escherichia coli infection);05132(Salmonella infection);05131(Shigellosis);05100(Bacterial invasion of epithelial cells);05100(Bacterial invasion of epithelial cells)","K05754","NA","actin related protein 2/3 complex subunit 5 like [Source:HGNC Symbol;Acc:HGNC:23366]",{"v":4.33737952243767,"d":"4.34"},{"v":0.760562448199446,"d":"0.76"},{"v":5.70285784251638,"d":"5.70"},{"v":2.51168507050303,"d":"2.51"},{"v":0.000288961268328616,"d":"0.00"},{"v":0.0322191814186406,"d":"0.03"},"up","yes"]
["ENSG00000175066","GK5","ENST00000486459;ENST00000460515;ENST00000489085;ENST00000480757;ENST00000392993;ENST00000463349;ENST00000460544;ENST00000460630;ENST00000487672;ENST00000492097","GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0016773(phosphotransferase activity, alcohol group as acceptor);GO:0005975(carbohydrate metabolic process);GO:0005739(mitochondrion);GO:0004370(glycerol kinase activity);GO:0006071(glycerol metabolic process);GO:0019563(glycerol catabolic process);GO:0006641(triglyceride metabolic process);GO:0046167(glycerol-3-phosphate biosynthetic process);GO:0046167(glycerol-3-phosphate biosynthetic process)","NA","NA","NA","glycerol kinase 5 (putative) [Source:HGNC Symbol;Acc:HGNC:28635]",{"v":0.864982925810166,"d":"0.86"},{"v":0.149425599605198,"d":"0.15"},{"v":5.78871979162583,"d":"5.79"},{"v":2.53324432325951,"d":"2.53"},{"v":0.000294585603826405,"d":"0.00"},{"v":0.0324185576128426,"d":"0.03"},"up","yes"]
["ENSG00000171150","SOCS5","ENST00000306503;ENST00000394861","GO:0016567(protein ubiquitination);GO:0035556(intracellular signal transduction);GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0007259(JAK-STAT cascade);GO:0007173(epidermal growth factor receptor signaling pathway);GO:0005829(cytosol);GO:0040008(regulation of growth);GO:0043687(post-translational protein modification);GO:0004860(protein kinase inhibitor activity);GO:0019221(cytokine-mediated signaling pathway);GO:0046426(negative regulation of JAK-STAT cascade);GO:0030971(receptor tyrosine kinase binding);GO:0009968(negative regulation of signal transduction);GO:0016049(cell growth);GO:0032436(positive regulation of proteasomal ubiquitin-dependent protein catabolic process);GO:0005154(epidermal growth factor receptor binding);GO:0007175(negative regulation of epidermal growth factor-activated receptor activity);GO:0032715(negative regulation of interleukin-6 production);GO:0045627(positive regulation of T-helper 1 cell differentiation);GO:0045629(negative regulation of T-helper 2 cell differentiation);GO:0050728(negative regulation of inflammatory response);GO:0071404(cellular response to low-density lipoprotein particle stimulus);GO:0071638(negative regulation of monocyte chemotactic protein-1 production);GO:0097699(vascular endothelial cell response to fluid shear stress);GO:0097699(vascular endothelial cell response to fluid shear stress)","04630(Jak-STAT signaling pathway);04917(Prolactin signaling pathway);04917(Prolactin signaling pathway)","K04698","NA","suppressor of cytokine signaling 5 [Source:HGNC Symbol;Acc:HGNC:16852]",{"v":0.15492863667064,"d":"0.15"},{"v":0.978275517679777,"d":"0.98"},{"v":0.158369123902939,"d":"0.16"},{"v":-2.65863700400343,"d":"-2.66"},{"v":0.000297161252949688,"d":"0.00"},{"v":0.0324185576128426,"d":"0.03"},"down","yes"]
["MSTRG.13080","SLC35B2","ENST00000615337;ENST00000538577;ENST00000619636;ENST00000393812;ENST00000393810","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0006810(transport);GO:0055085(transmembrane transport);GO:0005794(Golgi apparatus);GO:0004871(signal transducer activity);GO:0000139(Golgi membrane);GO:0007165(signal transduction);GO:0030176(integral component of endoplasmic reticulum membrane);GO:0030173(integral component of Golgi membrane);GO:0043123(positive regulation of I-kappaB kinase/NF-kappaB signaling);GO:0050428(3'-phosphoadenosine 5'-phosphosulfate biosynthetic process);GO:0046964(3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity);GO:0046963(3'-phosphoadenosine 5'-phosphosulfate transport);GO:1902559(3'-phospho-5'-adenylyl sulfate transmembrane transport);GO:1902559(3'-phospho-5'-adenylyl sulfate transmembrane transport)","NA","NA","NA","solute carrier family 35 member B2 [Source:HGNC Symbol;Acc:HGNC:16872]",{"v":5.33280750825222,"d":"5.33"},{"v":0.928103198476513,"d":"0.93"},{"v":5.74592083833571,"d":"5.75"},{"v":2.52253811696943,"d":"2.52"},{"v":0.000298825767731733,"d":"0.00"},{"v":0.0324185576128426,"d":"0.03"},"up","yes"]
["ENSG00000274211","SOCS7","ENST00000617360;ENST00000612932;ENST00000613678;ENST00000617765","GO:0005829(cytosol);GO:0016567(protein ubiquitination);GO:0035556(intracellular signal transduction);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0008150(biological_process);GO:0040008(regulation of growth);GO:0004860(protein kinase inhibitor activity);GO:0006469(negative regulation of protein kinase activity);GO:0019221(cytokine-mediated signaling pathway);GO:0046426(negative regulation of JAK-STAT cascade);GO:0017124(SH3 domain binding);GO:0009968(negative regulation of signal transduction);GO:0008286(insulin receptor signaling pathway);GO:0021799(cerebral cortex radially oriented cell migration);GO:0021819(layer formation in cerebral cortex);GO:0021942(radial glia guided migration of Purkinje cell);GO:0045444(fat cell differentiation);GO:0045444(fat cell differentiation)","04630(Jak-STAT signaling pathway);04917(Prolactin signaling pathway);04917(Prolactin signaling pathway)","K04699","NA","suppressor of cytokine signaling 7 [Source:HGNC Symbol;Acc:HGNC:29846]",{"v":1.27318079839926,"d":"1.27"},{"v":0.225043961257395,"d":"0.23"},{"v":5.65747594952372,"d":"5.66"},{"v":2.50015854646935,"d":"2.50"},{"v":3.14212569356113E-4,"d":"0.00"},{"v":0.0337834621445206,"d":"0.03"},"up","yes"]
["ENSG00000124459","ZNF45","ENST00000589703;ENST00000588432;ENST00000269973;ENST00000588140","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0005654(nucleoplasm);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0005622(intracellular);GO:0007275(multicellular organism development);GO:0006367(transcription initiation from RNA polymerase II promoter);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding)","NA","NA","NA","zinc finger protein 45 [Source:HGNC Symbol;Acc:HGNC:13111]",{"v":0.223564921010699,"d":"0.22"},{"v":1.35559714272707,"d":"1.36"},{"v":0.164919882142088,"d":"0.16"},{"v":-2.60016275955218,"d":"-2.60"},{"v":0.000321236835693485,"d":"0.00"},{"v":0.0342330440302739,"d":"0.03"},"down","yes"]
["MSTRG.12516","CCNJL","ENST00000393977;ENST00000257536;ENST00000520748;ENST00000519673;ENST00000377503","GO:0005634(nucleus);GO:0005515(protein binding);GO:0005515(protein binding)","NA","NA","NA","cyclin J like [Source:HGNC Symbol;Acc:HGNC:25876]",{"v":1.08798935472973,"d":"1.09"},{"v":6.28861192567568,"d":"6.29"},{"v":0.173009460209747,"d":"0.17"},{"v":-2.53107716786618,"d":"-2.53"},{"v":3.28716916033246E-4,"d":"0.00"},{"v":0.0347228868673013,"d":"0.03"},"down","yes"]
["MSTRG.12997","CDKN1A","ENST00000244741;ENST00000405375;ENST00000615513;ENST00000448526;ENST00000462537;ENST00000373711","GO:0008285(negative regulation of cell proliferation);GO:0005634(nucleus);GO:0048146(positive regulation of fibroblast proliferation);GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0005654(nucleoplasm);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0005515(protein binding);GO:0007049(cell cycle);GO:0016604(nuclear body);GO:0007050(cell cycle arrest);GO:0004860(protein kinase inhibitor activity);GO:0004861(cyclin-dependent protein serine/threonine kinase inhibitor activity);GO:0007346(regulation of mitotic cell cycle);GO:0072331(signal transduction by p53 class mediator);GO:0006977(DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest);GO:0005829(cytosol);GO:0031625(ubiquitin protein ligase binding);GO:0043234(protein complex);GO:0000082(G1/S transition of mitotic cell cycle);GO:0005730(nucleolus);GO:0030308(negative regulation of cell growth);GO:0071493(cellular response to UV-B);GO:0000079(regulation of cyclin-dependent protein serine/threonine kinase activity);GO:0034198(cellular response to amino acid starvation);GO:0004693(cyclin-dependent protein serine/threonine kinase activity);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:2000379(positive regulation of reactive oxygen species metabolic process);GO:0007265(Ras protein signal transduction);GO:0090398(cellular senescence);GO:0006974(cellular response to DNA damage stimulus);GO:0071479(cellular response to ionizing radiation);GO:0050821(protein stabilization);GO:0000307(cyclin-dependent protein kinase holoenzyme complex);GO:0070557(PCNA-p21 complex);GO:0019901(protein kinase binding);GO:0032403(protein complex binding);GO:0019912(cyclin-dependent protein kinase activating kinase activity);GO:0000086(G2/M transition of mitotic cell cycle);GO:0031668(cellular response to extracellular stimulus);GO:0042326(negative regulation of phosphorylation);GO:0045860(positive regulation of protein kinase activity);GO:0090400(stress-induced premature senescence);GO:0097193(intrinsic apoptotic signaling pathway);GO:1904030(negative regulation of cyclin-dependent protein kinase activity);GO:1904031(positive regulation of cyclin-dependent protein kinase activity);GO:2000134(negative regulation of G1/S transition of mitotic cell cycle);GO:0030332(cyclin binding);GO:0006978(DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator);GO:0009411(response to UV);GO:0009636(response to toxic substance);GO:0010033(response to organic substance);GO:0010165(response to X-ray);GO:0010243(response to organonitrogen compound);GO:0010629(negative regulation of gene expression);GO:0010942(positive regulation of cell death);GO:0014070(response to organic cyclic compound);GO:0030890(positive regulation of B cell proliferation);GO:0031100(animal organ regeneration);GO:0033158(regulation of protein import into nucleus, translocation);GO:0034605(cellular response to heat);GO:0042493(response to drug);GO:0042771(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator);GO:0043066(negative regulation of apoptotic process);GO:0043068(positive regulation of programmed cell death);GO:0045736(negative regulation of cyclin-dependent protein serine/threonine kinase activity);GO:0046685(response to arsenic-containing substance);GO:0051384(response to glucocorticoid);GO:0051412(response to corticosterone);GO:0051726(regulation of cell cycle);GO:0055093(response to hyperoxia);GO:0060574(intestinal epithelial cell maturation);GO:0071480(cellular response to gamma radiation);GO:0071850(mitotic cell cycle arrest);GO:0090399(replicative senescence);GO:2000278(regulation of DNA biosynthetic process);GO:0048471(perinuclear region of cytoplasm);GO:0048471(perinuclear region of cytoplasm)","04012(ErbB signaling pathway);04630(Jak-STAT signaling pathway);04066(HIF-1 signaling pathway);04068(FoxO signaling pathway);04151(PI3K-Akt signaling pathway);04110(Cell cycle);04115(p53 signaling pathway);04218(Cellular senescence);04921(Oxytocin signaling pathway);05200(Pathways in cancer);05202(Transcriptional misregulation in cancers);05206(MicroRNAs in cancer);05205(Proteoglycans in cancer);05203(Viral carcinogenesis);05210(Colorectal cancer);05212(Pancreatic cancer);05225(Hepatocellular carcinoma);05226(Gastric cancer);05214(Glioma);05216(Thyroid cancer);05220(Chronic myeloid leukemia);05217(Basal cell carcinoma);05218(Melanoma);05211(Renal cell carcinoma);05219(Bladder cancer);05215(Prostate cancer);05213(Endometrial cancer);05224(Breast cancer);05222(Small cell lung cancer);05223(Non-small cell lung cancer);05166(HTLV-I infection);05161(Hepatitis B);05160(Hepatitis C);05167(Kaposi's sarcoma-associated herpesvirus infection);05169(Epstein-Barr virus infection);05165(Human papillomavirus infection);01524(Platinum drug resistance);01522(Endocrine resistance);01522(Endocrine resistance)","K06625","NA","cyclin dependent kinase inhibitor 1A [Source:HGNC Symbol;Acc:HGNC:1784]",{"v":1.7330558357377,"d":"1.73"},{"v":9.97890225016394,"d":"9.98"},{"v":0.173671992398686,"d":"0.17"},{"v":-2.52556298151531,"d":"-2.53"},{"v":3.34670762780154E-4,"d":"0.00"},{"v":0.0348525921216919,"d":"0.03"},"down","yes"]
["ENSG00000198081","ZBTB14","ENST00000357006;ENST00000585253;ENST00000582388;ENST00000400143;ENST00000578327;ENST00000615385","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0005730(nucleolus);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0005515(protein binding);GO:0016235(aggresome);GO:0043565(sequence-specific DNA binding);GO:0044212(transcription regulatory region DNA binding);GO:0045892(negative regulation of transcription, DNA-templated);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:0001078(transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0003170(heart valve development);GO:0003279(cardiac septum development);GO:0060976(coronary vasculature development);GO:0060976(coronary vasculature development)","NA","NA","NA","zinc finger and BTB domain containing 14 [Source:HGNC Symbol;Acc:HGNC:12860]",{"v":3.61981664587379,"d":"3.62"},{"v":0.649914388349515,"d":"0.65"},{"v":5.56968227010094,"d":"5.57"},{"v":2.47759502946403,"d":"2.48"},{"v":3.35733323876122E-4,"d":"0.00"},{"v":0.0348525921216919,"d":"0.03"},"up","yes"]
["MSTRG.3803","ORAI1","ENST00000617316;ENST00000611718","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0002115(store-operated calcium entry);GO:0061180(mammary gland epithelium development);GO:0070509(calcium ion import);GO:0016323(basolateral plasma membrane);GO:0043234(protein complex);GO:0043234(protein complex)","NA","NA","NA","ORAI calcium release-activated calcium modulator 1 [Source:HGNC Symbol;Acc:HGNC:25896]",{"v":15.8482802882405,"d":"15.85"},{"v":2.88830113704686,"d":"2.89"},{"v":5.48705953301135,"d":"5.49"},{"v":2.45603322871727,"d":"2.46"},{"v":0.000343627572529,"d":"0.00"},{"v":0.0353672070802924,"d":"0.04"},"up","yes"]
["MSTRG.11047","PROK2","ENST00000353065;ENST00000295619","GO:0005623(cell);GO:0005576(extracellular region);GO:0048511(rhythmic process);GO:0007186(G-protein coupled receptor signaling pathway);GO:0007218(neuropeptide signaling pathway);GO:0007283(spermatogenesis);GO:0006935(chemotaxis);GO:0006954(inflammatory response);GO:0008283(cell proliferation);GO:0043066(negative regulation of apoptotic process);GO:0001664(G-protein coupled receptor binding);GO:0001525(angiogenesis);GO:0007204(positive regulation of cytosolic calcium ion concentration);GO:0000187(activation of MAPK activity);GO:0019233(sensory perception of pain);GO:0008284(positive regulation of cell proliferation);GO:0045987(positive regulation of smooth muscle contraction);GO:0007623(circadian rhythm);GO:0045765(regulation of angiogenesis);GO:0045765(regulation of angiogenesis)","NA","NA","NA","prokineticin 2 [Source:HGNC Symbol;Acc:HGNC:18455]",{"v":5.21250927853598,"d":"5.21"},{"v":29.5196482289082,"d":"29.52"},{"v":0.176577621728955,"d":"0.18"},{"v":-2.50162557787135,"d":"-2.50"},{"v":0.000350520873845256,"d":"0.00"},{"v":0.035734287351604,"d":"0.04"},"down","yes"]
["ENSG00000134827","TCN1","ENST00000257264;ENST00000529251;ENST00000534531","GO:0006810(transport);GO:0006811(ion transport);GO:0005576(extracellular region);GO:0005615(extracellular space);GO:0031419(cobalamin binding);GO:0015889(cobalamin transport);GO:0043312(neutrophil degranulation);GO:0035580(specific granule lumen);GO:1904724(tertiary granule lumen);GO:0009235(cobalamin metabolic process);GO:0006824(cobalt ion transport);GO:0006824(cobalt ion transport)","NA","NA","NA","transcobalamin 1 [Source:HGNC Symbol;Acc:HGNC:11652]",{"v":0.705887203026482,"d":"0.71"},{"v":4.16037819672131,"d":"4.16"},{"v":0.169668998742175,"d":"0.17"},{"v":-2.55920510953948,"d":"-2.56"},{"v":0.000354167728122373,"d":"0.00"},{"v":0.035734287351604,"d":"0.04"},"down","yes"]
["ENSG00000261150","EPPK1","ENST00000568225;ENST00000615648","GO:0045111(intermediate filament cytoskeleton);GO:0005856(cytoskeleton);GO:0008092(cytoskeletal protein binding);GO:0008092(cytoskeletal protein binding)","NA","NA","NA","epiplakin 1 [Source:HGNC Symbol;Acc:HGNC:15577]",{"v":0.373084,"d":"0.37"},{"v":0.0651625290588676,"d":"0.07"},{"v":5.72543769231175,"d":"5.73"},{"v":2.51738598707692,"d":"2.52"},{"v":0.000358961651085539,"d":"0.00"},{"v":0.035734287351604,"d":"0.04"},"up","yes"]
["ENSG00000237984","PTENP1","ENST00000532280;ENST00000447117","NA","NA","NA","NA","phosphatase and tensin homolog pseudogene 1 [Source:HGNC Symbol;Acc:HGNC:9589]",{"v":0.191043,"d":"0.19"},{"v":1.152007,"d":"1.15"},{"v":0.165834929822475,"d":"0.17"},{"v":-2.59218018109265,"d":"-2.59"},{"v":0.00035906400677164,"d":"0.00"},{"v":0.035734287351604,"d":"0.04"},"down","yes"]
["ENSG00000155254","MARVELD1","ENST00000285605;ENST00000451097","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005886(plasma membrane);GO:0005856(cytoskeleton);GO:0007049(cell cycle);GO:0008104(protein localization);GO:0019911(structural constituent of myelin sheath);GO:0042552(myelination);GO:0045121(membrane raft);GO:0001766(membrane raft polarization);GO:0001766(membrane raft polarization)","NA","NA","NA","MARVEL domain containing 1 [Source:HGNC Symbol;Acc:HGNC:28674]",{"v":0.709988689257177,"d":"0.71"},{"v":4.09106940781296,"d":"4.09"},{"v":0.173545989687017,"d":"0.17"},{"v":-2.52661006723449,"d":"-2.53"},{"v":0.000367247714212173,"d":"0.00"},{"v":0.0362491555290409,"d":"0.04"},"down","yes"]
["ENSG00000123595","RAB9A","ENST00000464506;ENST00000243325","GO:0006810(transport);GO:0016020(membrane);GO:0015031(protein transport);GO:0005525(GTP binding);GO:0000166(nucleotide binding);GO:0003924(GTPase activity);GO:0005794(Golgi apparatus);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0042470(melanosome);GO:0000139(Golgi membrane);GO:0030659(cytoplasmic vesicle membrane);GO:0031410(cytoplasmic vesicle);GO:0005768(endosome);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0030670(phagocytic vesicle membrane);GO:0061024(membrane organization);GO:0005770(late endosome);GO:0042147(retrograde transport, endosome to Golgi);GO:0032588(trans-Golgi network membrane);GO:0019003(GDP binding);GO:0045921(positive regulation of exocytosis);GO:0030133(transport vesicle);GO:0045335(phagocytic vesicle);GO:0005764(lysosome);GO:0052405(negative regulation by host of symbiont molecular function);GO:0032880(regulation of protein localization);GO:0032880(regulation of protein localization)","05162(Measles);05162(Measles)","K07899","NA","RAB9A, member RAS oncogene family [Source:HGNC Symbol;Acc:HGNC:9792]",{"v":0.648330760151086,"d":"0.65"},{"v":3.76578016525024,"d":"3.77"},{"v":0.172163730143818,"d":"0.17"},{"v":-2.5381468537384,"d":"-2.54"},{"v":0.000372695526514557,"d":"0.00"},{"v":0.0364878010592544,"d":"0.04"},"down","yes"]
["MSTRG.9621","CD93","ENST00000246006","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0030246(carbohydrate binding);GO:0005509(calcium ion binding);GO:0007155(cell adhesion);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0004872(receptor activity);GO:0016032(viral process);GO:0031012(extracellular matrix);GO:0043312(neutrophil degranulation);GO:0035579(specific granule membrane);GO:0070821(tertiary granule membrane);GO:0042116(macrophage activation);GO:0030667(secretory granule membrane);GO:0006909(phagocytosis);GO:0016337(single organismal cell-cell adhesion);GO:0101003(ficolin-1-rich granule membrane);GO:0001849(complement component C1q binding);GO:0009986(cell surface);GO:0031410(cytoplasmic vesicle)","NA","NA","NA","CD93 molecule [Source:HGNC Symbol;Acc:HGNC:15855]",{"v":16.795315,"d":"16.80"},{"v":3.129001,"d":"3.13"},{"v":5.36762851785602,"d":"5.37"},{"v":2.42428482914019,"d":"2.42"},{"v":0.000378976260431134,"d":"0.00"},{"v":0.0367482768359882,"d":"0.04"},"up","yes"]
["ENSG00000174206","C12orf66","ENST00000311915;ENST00000540673;ENST00000398055;ENST00000544871","GO:0016020(membrane);GO:0005765(lysosomal membrane);GO:0005764(lysosome);GO:1904262(negative regulation of TORC1 signaling);GO:0042149(cellular response to glucose starvation);GO:0061462(protein localization to lysosome);GO:0034198(cellular response to amino acid starvation);GO:0140007(KICSTOR complex);GO:0140007(KICSTOR complex)","NA","NA","NA","chromosome 12 open reading frame 66 [Source:HGNC Symbol;Acc:HGNC:26517]",{"v":0.701759491415236,"d":"0.70"},{"v":0.122384140356726,"d":"0.12"},{"v":5.73407215485392,"d":"5.73"},{"v":2.5195600588852,"d":"2.52"},{"v":0.000381459442326734,"d":"0.00"},{"v":0.0367482768359882,"d":"0.04"},"up","yes"]
["ENSG00000065923","SLC9A7","ENST00000616978;ENST00000491894;ENST00000464933;ENST00000328306","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0043231(intracellular membrane-bounded organelle);GO:0055085(transmembrane transport);GO:0005794(Golgi apparatus);GO:0042803(protein homodimerization activity);GO:0006811(ion transport);GO:0006813(potassium ion transport);GO:0015297(antiporter activity);GO:0015299(solute:proton antiporter activity);GO:0015385(sodium:proton antiporter activity);GO:0006812(cation transport);GO:0006814(sodium ion transport);GO:0006885(regulation of pH);GO:0035725(sodium ion transmembrane transport);GO:1902600(hydrogen ion transmembrane transport);GO:0071805(potassium ion transmembrane transport);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0005768(endosome);GO:0005802(trans-Golgi network);GO:0055038(recycling endosome membrane);GO:0000139(Golgi membrane);GO:0051453(regulation of intracellular pH);GO:0098719(sodium ion import across plasma membrane);GO:0015386(potassium:proton antiporter activity);GO:0015386(potassium:proton antiporter activity)","NA","NA","NA","solute carrier family 9 member A7 [Source:HGNC Symbol;Acc:HGNC:17123]",{"v":0.544646879098973,"d":"0.54"},{"v":0.0972527198245789,"d":"0.10"},{"v":5.60032542104106,"d":"5.60"},{"v":2.48551066104196,"d":"2.49"},{"v":0.000406425680774578,"d":"0.00"},{"v":0.0384727634592451,"d":"0.04"},"up","yes"]
["MSTRG.5523","MSRB1","ENST00000361871;ENST00000622125;ENST00000489198;ENST00000399753;ENST00000473663;ENST00000564908","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0003779(actin binding);GO:0005856(cytoskeleton);GO:0002376(immune system process);GO:0045087(innate immune response);GO:0006979(response to oxidative stress);GO:0016671(oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor);GO:0033743(peptide-methionine (R)-S-oxide reductase activity);GO:0030091(protein repair);GO:0005575(cellular_component);GO:0005829(cytosol);GO:0030041(actin filament polymerization);GO:0015629(actin cytoskeleton);GO:0008270(zinc ion binding);GO:0070191(methionine-R-sulfoxide reductase activity);GO:0005654(nucleoplasm);GO:0005654(nucleoplasm)","NA","NA","NA","methionine sulfoxide reductase B1 [Source:HGNC Symbol;Acc:HGNC:14133]",{"v":16.7240544343996,"d":"16.72"},{"v":92.1813321177561,"d":"92.18"},{"v":0.181425610263862,"d":"0.18"},{"v":-2.46254997202673,"d":"-2.46"},{"v":0.000406746295875697,"d":"0.00"},{"v":0.0384727634592451,"d":"0.04"},"down","yes"]
["ENSG00000233355","CHRM3-AS2","ENST00000596999;ENST00000428176;ENST00000610890;ENST00000427859;ENST00000458325","NA","NA","NA","NA","CHRM3 antisense RNA 2 [Source:HGNC Symbol;Acc:HGNC:43725]",{"v":1.67140259979424,"d":"1.67"},{"v":0.297561378600823,"d":"0.30"},{"v":5.61700112982881,"d":"5.62"},{"v":2.48980009310671,"d":"2.49"},{"v":0.000408944836637052,"d":"0.00"},{"v":0.0384727634592451,"d":"0.04"},"up","yes"]
["MSTRG.6219","MAP1LC3B","ENST00000268607;ENST00000562778;ENST00000570189;ENST00000564844;ENST00000564638;ENST00000565788;ENST00000561823","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0005874(microtubule);GO:0006914(autophagy);GO:0031410(cytoplasmic vesicle);GO:0005829(cytosol);GO:0000421(autophagosome membrane);GO:0061024(membrane organization);GO:0005930(axoneme);GO:0000045(autophagosome assembly);GO:0006995(cellular response to nitrogen starvation);GO:0012505(endomembrane system);GO:0009267(cellular response to starvation);GO:0031625(ubiquitin protein ligase binding);GO:0005776(autophagosome);GO:0031090(organelle membrane);GO:0005739(mitochondrion);GO:0005622(intracellular);GO:0016236(macroautophagy);GO:0097352(autophagosome maturation);GO:0000422(mitophagy);GO:0000422(mitophagy)","04216(Ferroptosis);04216(Ferroptosis)","K10435","NA","microtubule associated protein 1 light chain 3 beta [Source:HGNC Symbol;Acc:HGNC:13352]",{"v":2.01019256841709,"d":"2.01"},{"v":11.0834806854884,"d":"11.08"},{"v":0.181368346772962,"d":"0.18"},{"v":-2.46300540273845,"d":"-2.46"},{"v":0.000426172911649638,"d":"0.00"},{"v":0.0397827457525964,"d":"0.04"},"down","yes"]
["MSTRG.3410","COPZ1","ENST00000262061;ENST00000550171;ENST00000552218;ENST00000550713;MSTRG.3410.2;ENST00000551412;ENST00000548753;ENST00000550027;MSTRG.3410.1;ENST00000553231;ENST00000553009;ENST00000549116;ENST00000548281;ENST00000549043;ENST00000552362;ENST00000455864;ENST00000551779","GO:0006810(transport);GO:0006886(intracellular protein transport);GO:0015031(protein transport);GO:0016192(vesicle-mediated transport);GO:0030117(membrane coat);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005794(Golgi apparatus);GO:0000139(Golgi membrane);GO:0031410(cytoplasmic vesicle);GO:0030663(COPI-coated vesicle membrane);GO:0005789(endoplasmic reticulum membrane);GO:0005829(cytosol);GO:0006890(retrograde vesicle-mediated transport, Golgi to ER);GO:0006888(ER to Golgi vesicle-mediated transport);GO:0030133(transport vesicle);GO:0006891(intra-Golgi vesicle-mediated transport);GO:0030126(COPI vesicle coat);GO:1901998(toxin transport);GO:1901998(toxin transport)","NA","NA","NA","coatomer protein complex subunit zeta 1 [Source:HGNC Symbol;Acc:HGNC:2243]",{"v":1.84446160675298,"d":"1.84"},{"v":10.1982490510282,"d":"10.20"},{"v":0.180860616123806,"d":"0.18"},{"v":-2.46704981135507,"d":"-2.47"},{"v":0.000430930408197197,"d":"0.00"},{"v":0.0399174151962357,"d":"0.04"},"down","yes"]
["MSTRG.8175","CCDC97","ENST00000269967;ENST00000600918;ENST00000596882","GO:0005686(U2 snRNP);GO:0005686(U2 snRNP)","NA","NA","NA","coiled-coil domain containing 97 [Source:HGNC Symbol;Acc:HGNC:28289]",{"v":2.54414642816017,"d":"2.54"},{"v":13.9300573807904,"d":"13.93"},{"v":0.182637182217825,"d":"0.18"},{"v":-2.45294758837971,"d":"-2.45"},{"v":0.000438692854382665,"d":"0.00"},{"v":0.0403262545990538,"d":"0.04"},"down","yes"]
["MSTRG.10875","CCR3","ENST00000395940;ENST00000475150;ENST00000484025;ENST00000545097;ENST00000357422;MSTRG.10875.2;ENST00000395942","GO:0045766(positive regulation of angiogenesis);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0004930(G-protein coupled receptor activity);GO:0007186(G-protein coupled receptor signaling pathway);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0004871(signal transducer activity);GO:0007165(signal transduction);GO:0004950(chemokine receptor activity);GO:0016493(C-C chemokine receptor activity);GO:0006935(chemotaxis);GO:0006954(inflammatory response);GO:0070098(chemokine-mediated signaling pathway);GO:0016032(viral process);GO:0005887(integral component of plasma membrane);GO:0007155(cell adhesion);GO:0007188(adenylate cyclase-modulating G-protein coupled receptor signaling pathway);GO:0007204(positive regulation of cytosolic calcium ion concentration);GO:0006968(cellular defense response);GO:0019957(C-C chemokine binding);GO:0001938(positive regulation of endothelial cell proliferation);GO:0001938(positive regulation of endothelial cell proliferation)","04060(Cytokine-cytokine receptor interaction);04062(Chemokine signaling pathway);05203(Viral carcinogenesis);05167(Kaposi's sarcoma-associated herpesvirus infection);05167(Kaposi's sarcoma-associated herpesvirus infection)","K04178","NA","C-C motif chemokine receptor 3 [Source:HGNC Symbol;Acc:HGNC:1604]",{"v":1.39889646542056,"d":"1.40"},{"v":7.64297322483311,"d":"7.64"},{"v":0.18303040247156,"d":"0.18"},{"v":-2.44984478598506,"d":"-2.45"},{"v":0.000465567018775226,"d":"0.00"},{"v":0.0424724093946309,"d":"0.04"},"down","yes"]
["ENSG00000181135","ZNF707","ENST00000532486;ENST00000532571;ENST00000527293;ENST00000531811;ENST00000508587;ENST00000532205;ENST00000418203;ENST00000532003;ENST00000525538;ENST00000534589;ENST00000442058;ENST00000525619;ENST00000358656;ENST00000525862;ENST00000528456;ENST00000531985;ENST00000533031;ENST00000531254;ENST00000533254;ENST00000534303;ENST00000530341","GO:0003676(nucleic acid binding);GO:0006355(regulation of transcription, DNA-templated);GO:0005622(intracellular);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0005515(protein binding)","NA","NA","NA","zinc finger protein 707 [Source:HGNC Symbol;Acc:HGNC:27815]",{"v":1.05629760312945,"d":"1.06"},{"v":0.190315041725936,"d":"0.19"},{"v":5.55025810650624,"d":"5.55"},{"v":2.47255486341197,"d":"2.47"},{"v":0.000483529541413153,"d":"0.00"},{"v":0.04376196246768,"d":"0.04"},"up","yes"]
["MSTRG.1728","UBE2D1","ENST00000373910;ENST00000473824;ENST00000606483;ENST00000615793","GO:0005737(cytoplasm);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0016740(transferase activity);GO:0016567(protein ubiquitination);GO:0004842(ubiquitin-protein transferase activity);GO:0061631(ubiquitin conjugating enzyme activity);GO:0000209(protein polyubiquitination);GO:1902916(positive regulation of protein polyubiquitination);GO:0005515(protein binding);GO:0006511(ubiquitin-dependent protein catabolic process);GO:0038095(Fc-epsilon receptor signaling pathway);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0002223(stimulatory C-type lectin receptor signaling pathway);GO:0016579(protein deubiquitination);GO:0031145(anaphase-promoting complex-dependent catabolic process);GO:0043161(proteasome-mediated ubiquitin-dependent protein catabolic process);GO:0050852(T cell receptor signaling pathway);GO:0051437(positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition);GO:0061418(regulation of transcription from RNA polymerase II promoter in response to hypoxia);GO:0031398(positive regulation of protein ubiquitination);GO:0043234(protein complex);GO:0035666(TRIF-dependent toll-like receptor signaling pathway);GO:0051436(negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle);GO:0030509(BMP signaling pathway);GO:0042787(protein ubiquitination involved in ubiquitin-dependent protein catabolic process);GO:0051439(regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle);GO:0070936(protein K48-linked ubiquitination);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0000151(ubiquitin ligase complex);GO:0000151(ubiquitin ligase complex)","04141(Protein processing in endoplasmic reticulum);04120(Ubiquitin mediated proteolysis);04120(Ubiquitin mediated proteolysis)","K06689","EC:2.3.2.23","ubiquitin conjugating enzyme E2 D1 [Source:HGNC Symbol;Acc:HGNC:12474]",{"v":1.54488878542742,"d":"1.54"},{"v":8.42350153126793,"d":"8.42"},{"v":0.183402208653113,"d":"0.18"},{"v":-2.44691708194291,"d":"-2.45"},{"v":0.000486970849582222,"d":"0.00"},{"v":0.04376196246768,"d":"0.04"},"down","yes"]
["MSTRG.5998","CMTM2","ENST00000532362;ENST00000268595;ENST00000379486","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005125(cytokine activity);GO:0005615(extracellular space);GO:0006935(chemotaxis);GO:0006935(chemotaxis)","NA","NA","NA","CKLF like MARVEL transmembrane domain containing 2 [Source:HGNC Symbol;Acc:HGNC:19173]",{"v":3.96022670112945,"d":"3.96"},{"v":21.5068589226759,"d":"21.51"},{"v":0.184137847156935,"d":"0.18"},{"v":-2.4411419103838,"d":"-2.44"},{"v":0.000510656912056866,"d":"0.00"},{"v":0.0452969114216958,"d":"0.05"},"down","yes"]
["ENSG00000179409","GEMIN4","ENST00000574958;ENST00000573482;ENST00000576778;ENST00000576383;ENST00000319004;ENST00000570364","GO:0006397(mRNA processing);GO:0008380(RNA splicing);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005829(cytosol);GO:0005515(protein binding);GO:0016604(nuclear body);GO:0005730(nucleolus);GO:0000387(spliceosomal snRNP assembly);GO:0032797(SMN complex);GO:0006364(rRNA processing);GO:0005654(nucleoplasm);GO:0070062(extracellular exosome);GO:0051170(nuclear import);GO:0034719(SMN-Sm protein complex);GO:0097504(Gemini of coiled bodies);GO:0030532(small nuclear ribonucleoprotein complex);GO:0030532(small nuclear ribonucleoprotein complex)","03013(RNA transport);03013(RNA transport)","K13132","NA","gem nuclear organelle associated protein 4 [Source:HGNC Symbol;Acc:HGNC:15717]",{"v":0.853356201877934,"d":"0.85"},{"v":0.147756844374891,"d":"0.15"},{"v":5.77540895305523,"d":"5.78"},{"v":2.52992310646907,"d":"2.53"},{"v":0.000511574485413604,"d":"0.00"},{"v":0.0452969114216958,"d":"0.05"},"up","yes"]
["MSTRG.7801","S1PR5","ENST00000333430;ENST00000439028;ENST00000590601","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0004930(G-protein coupled receptor activity);GO:0007186(G-protein coupled receptor signaling pathway);GO:0005886(plasma membrane);GO:0004871(signal transducer activity);GO:0007165(signal transduction);GO:0038036(sphingosine-1-phosphate receptor activity);GO:0003376(sphingosine-1-phosphate signaling pathway);GO:0045664(regulation of neuron differentiation);GO:0045664(regulation of neuron differentiation)","04071(Sphingolipid signaling pathway);04080(Neuroactive ligand-receptor interaction);04080(Neuroactive ligand-receptor interaction)","K04295","NA","sphingosine-1-phosphate receptor 5 [Source:HGNC Symbol;Acc:HGNC:14299]",{"v":11.5390947138275,"d":"11.54"},{"v":2.24666147469708,"d":"2.25"},{"v":5.13610743932097,"d":"5.14"},{"v":2.36067538169588,"d":"2.36"},{"v":0.000558537943760344,"d":"0.00"},{"v":0.049094262180745,"d":"0.05"},"up","yes"]
["ENSG00000001630","CYP51A1","ENST00000003100;ENST00000450723","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0046872(metal ion binding);GO:0005783(endoplasmic reticulum);GO:0004497(monooxygenase activity);GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0005506(iron ion binding);GO:0016705(oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen);GO:0020037(heme binding);GO:0008398(sterol 14-demethylase activity);GO:0033488(cholesterol biosynthetic process via 24,25-dihydrolanosterol);GO:0070988(demethylation);GO:0043231(intracellular membrane-bounded organelle);GO:0006629(lipid metabolic process);GO:0005789(endoplasmic reticulum membrane);GO:0006694(steroid biosynthetic process);GO:0008202(steroid metabolic process);GO:0016126(sterol biosynthetic process);GO:0008203(cholesterol metabolic process);GO:0005886(plasma membrane);GO:0006695(cholesterol biosynthetic process);GO:0031090(organelle membrane);GO:0045540(regulation of cholesterol biosynthetic process);GO:0016125(sterol metabolic process);GO:0016125(sterol metabolic process)","00100(Steroid biosynthesis);00100(Steroid biosynthesis)","K05917","EC:1.14.13.70","cytochrome P450 family 51 subfamily A member 1 [Source:HGNC Symbol;Acc:HGNC:2649]",{"v":0.216587540500736,"d":"0.22"},{"v":1.20771030756014,"d":"1.21"},{"v":0.179337328782342,"d":"0.18"},{"v":-2.4792522807248,"d":"-2.48"},{"v":0.000577187535271895,"d":"0.00"},{"v":0.0502001237486261,"d":"0.05"},"down","yes"]
["MSTRG.14933","TRAF1","ENST00000373887;ENST00000540010","GO:0008270(zinc ion binding);GO:0007165(signal transduction);GO:0042981(regulation of apoptotic process);GO:0005515(protein binding);GO:0006915(apoptotic process);GO:0051092(positive regulation of NF-kappaB transcription factor activity);GO:0042802(identical protein binding);GO:0005829(cytosol);GO:0031625(ubiquitin protein ligase binding);GO:0005737(cytoplasm);GO:0006461(protein complex assembly);GO:0031996(thioesterase binding);GO:0005164(tumor necrosis factor receptor binding);GO:0010803(regulation of tumor necrosis factor-mediated signaling pathway);GO:2001236(regulation of extrinsic apoptotic signaling pathway);GO:2001236(regulation of extrinsic apoptotic signaling pathway)","04064(NF-kappa B signaling pathway);04668(TNF signaling pathway);04210(Apoptosis);05200(Pathways in cancer);05202(Transcriptional misregulation in cancers);05203(Viral carcinogenesis);05222(Small cell lung cancer);05168(Herpes simplex infection);05169(Epstein-Barr virus infection);05169(Epstein-Barr virus infection)","K03172","NA","TNF receptor associated factor 1 [Source:HGNC Symbol;Acc:HGNC:12031]",{"v":7.11941289192123,"d":"7.12"},{"v":1.40237274120019,"d":"1.40"},{"v":5.07669087023771,"d":"5.08"},{"v":2.34388841418353,"d":"2.34"},{"v":0.000579456668415464,"d":"0.00"},{"v":0.0502001237486261,"d":"0.05"},"up","yes"]
["MSTRG.12202","LUCAT1;AC123595.2","ENST00000511918;ENST00000513492;ENST00000607854;ENST00000513626","NA","NA","NA","NA","lung cancer associated transcript 1 (non-protein coding) [Source:HGNC Symbol;Acc:HGNC:48498]",{"v":0.505463005165289,"d":"0.51"},{"v":2.7143874600551,"d":"2.71"},{"v":0.186216232061074,"d":"0.19"},{"v":-2.42494925994264,"d":"-2.42"},{"v":0.000636620357102989,"d":"0.00"},{"v":0.0547584452873871,"d":"0.05"},"down","yes"]
["MSTRG.13286","VNN2","ENST00000326499;ENST00000392389;ENST00000418593;ENST00000533835;ENST00000525270;ENST00000422400;ENST00000525674;ENST00000528801;ENST00000530536;ENST00000532053;MSTRG.13286.5;ENST00000526157;ENST00000524919;MSTRG.13286.1;ENST00000525289;ENST00000526192;ENST00000531279;ENST00000532012;MSTRG.13286.6","GO:0016810(hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds);GO:0006807(nitrogen compound metabolic process);GO:0016811(hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides);GO:0016020(membrane);GO:0016787(hydrolase activity);GO:0005886(plasma membrane);GO:0031225(anchored component of membrane);GO:0005576(extracellular region);GO:0006501(C-terminal protein lipidation);GO:0006928(movement of cell or subcellular component);GO:0017159(pantetheine hydrolase activity);GO:0015939(pantothenate metabolic process);GO:0015939(pantothenate metabolic process)","00770(Pantothenate and CoA biosynthesis);00770(Pantothenate and CoA biosynthesis)","K08069","EC:3.5.1.92","vanin 2 [Source:HGNC Symbol;Acc:HGNC:12706]",{"v":28.2569241967338,"d":"28.26"},{"v":145.812262497152,"d":"145.81"},{"v":0.193789765776974,"d":"0.19"},{"v":-2.36743571222865,"d":"-2.37"},{"v":0.000647613667748922,"d":"0.00"},{"v":0.0553089630285995,"d":"0.06"},"down","yes"]
["MSTRG.11926","SPCS3","ENST00000503362;ENST00000507678;ENST00000507001;ENST00000513139","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016787(hydrolase activity);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0008233(peptidase activity);GO:0006508(proteolysis);GO:0006465(signal peptide processing);GO:0005787(signal peptidase complex);GO:0043231(intracellular membrane-bounded organelle);GO:0031090(organelle membrane);GO:0045047(protein targeting to ER);GO:0045047(protein targeting to ER)","03060(Protein export);03060(Protein export)","K12948","EC:3.4.-.-","signal peptidase complex subunit 3 [Source:HGNC Symbol;Acc:HGNC:26212]",{"v":1.19727297174645,"d":"1.20"},{"v":6.19256366125018,"d":"6.19"},{"v":0.193340438183681,"d":"0.19"},{"v":-2.37078467841645,"d":"-2.37"},{"v":0.000672739494881087,"d":"0.00"},{"v":0.0570197412783473,"d":"0.06"},"down","yes"]
["MSTRG.8626","QPCT","ENST00000338415;ENST00000404976;ENST00000444022;ENST00000469098;ENST00000480050;ENST00000470075","GO:0046872(metal ion binding);GO:0016740(transferase activity);GO:0016746(transferase activity, transferring acyl groups);GO:0008270(zinc ion binding);GO:0005576(extracellular region);GO:0070062(extracellular exosome);GO:0043312(neutrophil degranulation);GO:1904813(ficolin-1-rich granule lumen);GO:0006464(cellular protein modification process);GO:0035580(specific granule lumen);GO:1904724(tertiary granule lumen);GO:0016603(glutaminyl-peptide cyclotransferase activity);GO:0017186(peptidyl-pyroglutamic acid biosynthetic process, using glutaminyl-peptide cyclotransferase);GO:0017186(peptidyl-pyroglutamic acid biosynthetic process, using glutaminyl-peptide cyclotransferase)","NA","NA","NA","glutaminyl-peptide cyclotransferase [Source:HGNC Symbol;Acc:HGNC:9753]",{"v":8.27352319469027,"d":"8.27"},{"v":42.5327329049634,"d":"42.53"},{"v":0.194521316398288,"d":"0.19"},{"v":-2.36199983490973,"d":"-2.36"},{"v":6.77115346520816E-4,"d":"0.00"},{"v":0.0570197412783473,"d":"0.06"},"down","yes"]
["ENSG00000166275","BORCS7","ENST00000339834;ENST00000369883;ENST00000478833","GO:0016020(membrane);GO:0005765(lysosomal membrane);GO:0005764(lysosome);GO:0005515(protein binding);GO:0099078(BORC complex);GO:0099078(BORC complex)","NA","NA","NA","BLOC-1 related complex subunit 7 [Source:HGNC Symbol;Acc:HGNC:23516]",{"v":2.17579159231905,"d":"2.18"},{"v":0.41916335450517,"d":"0.42"},{"v":5.19079630634126,"d":"5.19"},{"v":2.37595587559391,"d":"2.38"},{"v":0.000691242996255669,"d":"0.00"},{"v":0.0578051955618803,"d":"0.06"},"up","yes"]
["MSTRG.2246","AC080023.2","MSTRG.2246.1;ENST00000532615","NA","NA","NA","NA",null,{"v":4.11584031219512,"d":"4.12"},{"v":0.783921014634146,"d":"0.78"},{"v":5.25032526920582,"d":"5.25"},{"v":2.39240680368046,"d":"2.39"},{"v":0.000712605896876578,"d":"0.00"},{"v":0.0591806911047431,"d":"0.06"},"up","yes"]
["MSTRG.7098","PRR29","ENST00000225760;ENST00000412177;ENST00000579222;ENST00000582530","NA","NA","NA","NA","proline rich 29 [Source:HGNC Symbol;Acc:HGNC:25673]",{"v":0.173447127233221,"d":"0.17"},{"v":0.954271066875905,"d":"0.95"},{"v":0.181758761481738,"d":"0.18"},{"v":-2.45990318553426,"d":"-2.46"},{"v":0.000743757445472192,"d":"0.00"},{"v":0.0611822004935189,"d":"0.06"},"down","yes"]
["ENSG00000102010","BMX","ENST00000348343","GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0005654(nucleoplasm);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0035556(intracellular signal transduction);GO:0007155(cell adhesion);GO:0004713(protein tyrosine kinase activity);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0007165(signal transduction);GO:0004715(non-membrane spanning protein tyrosine kinase activity);GO:0006915(apoptotic process);GO:0045087(innate immune response);GO:0005829(cytosol);GO:0032587(ruffle membrane);GO:0004871(signal transducer activity);GO:0042127(regulation of cell proliferation);GO:0006661(phosphatidylinositol biosynthetic process);GO:0046777(protein autophosphorylation);GO:0097194(execution phase of apoptosis);GO:0007498(mesoderm development);GO:0038083(peptidyl-tyrosine autophosphorylation);GO:0031234(extrinsic component of cytoplasmic side of plasma membrane);GO:0007169(transmembrane receptor protein tyrosine kinase signaling pathway);GO:0001865(NK T cell differentiation)","NA","NA","NA","BMX non-receptor tyrosine kinase [Source:HGNC Symbol;Acc:HGNC:1079]",{"v":0.344511854597292,"d":"0.34"},{"v":1.86571140627227,"d":"1.87"},{"v":0.184654418383835,"d":"0.18"},{"v":-2.43710031133553,"d":"-2.44"},{"v":0.000746867918331447,"d":"0.00"},{"v":0.0611822004935189,"d":"0.06"},"down","yes"]
["ENSG00000177311","ZBTB38","ENST00000514251;ENST00000513570;ENST00000512327;ENST00000507722;ENST00000509842;ENST00000510726;ENST00000510338;ENST00000509883;ENST00000509813;ENST00000504673;ENST00000441582;ENST00000513619;ENST00000636289;ENST00000512276;ENST00000507657;ENST00000513249","GO:0003676(nucleic acid binding);GO:0005654(nucleoplasm);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0005694(chromosome);GO:0042803(protein homodimerization activity);GO:0006974(cellular response to DNA damage stimulus);GO:0005515(protein binding);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0072562(blood microparticle);GO:0045892(negative regulation of transcription, DNA-templated);GO:0008327(methyl-CpG binding);GO:0006275(regulation of DNA replication);GO:0006275(regulation of DNA replication)","NA","NA","NA","zinc finger and BTB domain containing 38 [Source:HGNC Symbol;Acc:HGNC:26636]",{"v":1.95406165161834,"d":"1.95"},{"v":0.397818123429053,"d":"0.40"},{"v":4.91194728579737,"d":"4.91"},{"v":2.29629507802756,"d":"2.30"},{"v":0.000769375290690952,"d":"0.00"},{"v":0.0623491841867539,"d":"0.06"},"up","yes"]
["MSTRG.9138","SPOPL;AC092620.2","ENST00000280098;ENST00000430968;ENST00000420679;ENST00000458007;ENST00000449869;MSTRG.9138.3","GO:0005634(nucleus);GO:0016567(protein ubiquitination);GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0031625(ubiquitin protein ligase binding);GO:0030162(regulation of proteolysis);GO:0042787(protein ubiquitination involved in ubiquitin-dependent protein catabolic process);GO:0019005(SCF ubiquitin ligase complex);GO:0043161(proteasome-mediated ubiquitin-dependent protein catabolic process);GO:0031397(negative regulation of protein ubiquitination);GO:0031463(Cul3-RING ubiquitin ligase complex);GO:0031463(Cul3-RING ubiquitin ligase complex)","04340(Hedgehog signaling pathway);04340(Hedgehog signaling pathway)","K10523","NA","speckle type BTB/POZ protein like [Source:HGNC Symbol;Acc:HGNC:27934]",{"v":2.05180042628975,"d":"2.05"},{"v":10.3540457799293,"d":"10.35"},{"v":0.198164125395992,"d":"0.20"},{"v":-2.33523228674158,"d":"-2.34"},{"v":7.75954470386324E-4,"d":"0.00"},{"v":0.0623491841867539,"d":"0.06"},"down","yes"]
["MSTRG.14826","NFIL3","ENST00000297689","GO:0005634(nucleus);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0006366(transcription from RNA polymerase II promoter);GO:0005515(protein binding);GO:0000979(RNA polymerase II core promoter sequence-specific DNA binding);GO:0006955(immune response);GO:0007623(circadian rhythm);GO:0010628(positive regulation of gene expression);GO:0048511(rhythmic process);GO:0071353(cellular response to interleukin-4);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0003714(transcription corepressor activity);GO:0001078(transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0000977(RNA polymerase II regulatory region sequence-specific DNA binding)","NA","NA","NA","nuclear factor, interleukin 3 regulated [Source:HGNC Symbol;Acc:HGNC:7787]",{"v":6.394151,"d":"6.39"},{"v":1.294223,"d":"1.29"},{"v":4.94053265936396,"d":"4.94"},{"v":2.30466659314511,"d":"2.30"},{"v":0.000776646539446361,"d":"0.00"},{"v":0.0623491841867539,"d":"0.06"},"up","yes"]
["MSTRG.760","SORT1","ENST00000256637;ENST00000538502;ENST00000633956;ENST00000482236;ENST00000471996;ENST00000493736;ENST00000466471","GO:0048471(perinuclear region of cytoplasm);GO:0051005(negative regulation of lipoprotein lipase activity);GO:0006810(transport);GO:0005634(nucleus);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005794(Golgi apparatus);GO:0005829(cytosol);GO:0005765(lysosomal membrane);GO:0005886(plasma membrane);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005515(protein binding);GO:0007275(multicellular organism development);GO:0030154(cell differentiation);GO:0005764(lysosome);GO:0032580(Golgi cisterna membrane);GO:0005768(endosome);GO:0006897(endocytosis);GO:0010008(endosome membrane);GO:0001503(ossification);GO:0009986(cell surface);GO:0031965(nuclear membrane);GO:0016050(vesicle organization);GO:0031410(cytoplasmic vesicle);GO:0019899(enzyme binding);GO:0005769(early endosome);GO:0007186(G-protein coupled receptor signaling pathway);GO:0005905(clathrin-coated pit);GO:0008625(extrinsic apoptotic signaling pathway via death domain receptors);GO:0007218(neuropeptide signaling pathway);GO:0010468(regulation of gene expression);GO:0048406(nerve growth factor binding);GO:0046323(glucose import);GO:0032868(response to insulin);GO:0008333(endosome to lysosome transport);GO:0010465(nerve growth factor receptor activity);GO:0030379(neurotensin receptor activity, non-G-protein coupled);GO:0006895(Golgi to endosome transport);GO:0014902(myotube differentiation);GO:0032509(endosome transport via multivesicular body sorting pathway);GO:0038180(nerve growth factor signaling pathway);GO:0045599(negative regulation of fat cell differentiation);GO:0048011(neurotrophin TRK receptor signaling pathway);GO:0048227(plasma membrane to endosome transport);GO:1904037(positive regulation of epithelial cell apoptotic process);GO:0030136(clathrin-coated vesicle);GO:0030140(trans-Golgi network transport vesicle);GO:0030425(dendrite);GO:0030659(cytoplasmic vesicle membrane);GO:0043025(neuronal cell body);GO:0043231(intracellular membrane-bounded organelle);GO:0043231(intracellular membrane-bounded organelle)","04142(Lysosome);04979(Cholesterol metabolism);04722(Neurotrophin signaling pathway);04722(Neurotrophin signaling pathway)","K12388","NA","sortilin 1 [Source:HGNC Symbol;Acc:HGNC:11186]",{"v":0.977704555567686,"d":"0.98"},{"v":4.91132270873362,"d":"4.91"},{"v":0.199071536030217,"d":"0.20"},{"v":-2.32864114084909,"d":"-2.33"},{"v":0.000811170044361821,"d":"0.00"},{"v":0.0640423221444937,"d":"0.06"},"down","yes"]
["MSTRG.8670","CRIPT","ENST00000238892","GO:0005737(cytoplasm);GO:0005634(nucleus);GO:0005730(nucleolus);GO:0042995(cell projection);GO:0005515(protein binding);GO:0030054(cell junction);GO:0045202(synapse);GO:0030425(dendrite);GO:0008017(microtubule binding);GO:0014069(postsynaptic density);GO:0043197(dendritic spine);GO:0032403(protein complex binding);GO:0030165(PDZ domain binding);GO:0097110(scaffold protein binding);GO:0035372(protein localization to microtubule);GO:0045184(establishment of protein localization);GO:0043025(neuronal cell body);GO:0043198(dendritic shaft);GO:0031122(cytoplasmic microtubule organization);GO:1902897(regulation of postsynaptic density protein 95 clustering)","NA","NA","NA","CXXC repeat containing interactor of PDZ3 domain [Source:HGNC Symbol;Acc:HGNC:14312]",{"v":0.343779093713393,"d":"0.34"},{"v":1.82661703084733,"d":"1.83"},{"v":0.188205347868634,"d":"0.19"},{"v":-2.40962047195407,"d":"-2.41"},{"v":0.000821085896987138,"d":"0.00"},{"v":0.0640423221444937,"d":"0.06"},"down","yes"]
["MSTRG.2975","GSEC","ENST00000626810;ENST00000629441","NA","NA","NA","NA","G-quadruplex forming sequence containing lncRNA [Source:HGNC Symbol;Acc:HGNC:48645]",{"v":0.257273167606769,"d":"0.26"},{"v":1.3859129983884,"d":"1.39"},{"v":0.185634428644466,"d":"0.19"},{"v":-2.42946379051924,"d":"-2.43"},{"v":0.000823134521631551,"d":"0.00"},{"v":0.0640423221444937,"d":"0.06"},"down","yes"]
["MSTRG.15530","VBP1","ENST00000286428;ENST00000460509;ENST00000625964","GO:0043231(intracellular membrane-bounded organelle);GO:0005829(cytosol);GO:0006457(protein folding);GO:0016272(prefoldin complex);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005515(protein binding);GO:0005844(polysome);GO:0015631(tubulin binding);GO:0007017(microtubule-based process);GO:0007021(tubulin complex assembly);GO:0007021(tubulin complex assembly)","NA","NA","NA","VHL binding protein 1 [Source:HGNC Symbol;Acc:HGNC:12662]",{"v":1.02392250445986,"d":"1.02"},{"v":5.24917109811695,"d":"5.25"},{"v":0.19506365582695,"d":"0.20"},{"v":-2.35798309419629,"d":"-2.36"},{"v":0.000823333820295032,"d":"0.00"},{"v":0.0640423221444937,"d":"0.06"},"down","yes"]
["MSTRG.11292","MME","ENST00000360490;MSTRG.11292.5;ENST00000460393;ENST00000615825;ENST00000473730;ENST00000462745;ENST00000382989;ENST00000462837;ENST00000491597;ENST00000477669;ENST00000625667;ENST00000497890;ENST00000481828;ENST00000493888;ENST00000495577;ENST00000493237;MSTRG.11292.18;ENST00000616757","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0046872(metal ion binding);GO:0016787(hydrolase activity);GO:0008270(zinc ion binding);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0008233(peptidase activity);GO:0006508(proteolysis);GO:0045202(synapse);GO:0004222(metalloendopeptidase activity);GO:0008237(metallopeptidase activity);GO:0005925(focal adhesion);GO:0030425(dendrite);GO:0005887(integral component of plasma membrane);GO:0030424(axon);GO:0070062(extracellular exosome);GO:0005903(brush border);GO:0043312(neutrophil degranulation);GO:0030667(secretory granule membrane);GO:0008021(synaptic vesicle);GO:0004175(endopeptidase activity);GO:0042277(peptide binding);GO:0071493(cellular response to UV-B);GO:0001822(kidney development);GO:0071345(cellular response to cytokine stimulus);GO:0019233(sensory perception of pain);GO:0002003(angiotensin maturation);GO:0008238(exopeptidase activity);GO:0006518(peptide metabolic process);GO:0046449(creatinine metabolic process);GO:0050435(amyloid-beta metabolic process);GO:0071492(cellular response to UV-A);GO:0090399(replicative senescence);GO:0044306(neuron projection terminus);GO:0044306(neuron projection terminus)","04640(Hematopoietic cell lineage);04614(Renin-angiotensin system);04974(Protein digestion and absorption);05010(Alzheimer's disease);05010(Alzheimer's disease)","K01389","EC:3.4.24.11","membrane metalloendopeptidase [Source:HGNC Symbol;Acc:HGNC:7154]",{"v":3.19412064431197,"d":"3.19"},{"v":15.9364265352211,"d":"15.94"},{"v":0.200428912796269,"d":"0.20"},{"v":-2.31883745591986,"d":"-2.32"},{"v":0.000824328179072956,"d":"0.00"},{"v":0.0640423221444937,"d":"0.06"},"down","yes"]
["MSTRG.5103","CCPG1;DNAAF4-CCPG1;DNAAF4","ENST00000310958;ENST00000569205;ENST00000442196;ENST00000565113;ENST00000568372;ENST00000519017;ENST00000524160;ENST00000568592;MSTRG.5103.11;ENST00000321149;ENST00000564092;ENST00000563294;ENST00000425574;ENST00000522437;ENST00000448430;ENST00000570272;ENST00000568808;ENST00000563171;ENST00000564663","GO:2001106(regulation of Rho guanyl-nucleotide exchange factor activity);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0007049(cell cycle);GO:0003674(molecular_function);GO:0008284(positive regulation of cell proliferation);GO:0005515(protein binding);GO:0045787(positive regulation of cell cycle);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0007399(nervous system development);GO:0003341(cilium movement);GO:0030331(estrogen receptor binding);GO:0036159(inner dynein arm assembly);GO:0061136(regulation of proteasomal protein catabolic process);GO:0007368(determination of left/right symmetry);GO:0001764(neuron migration);GO:0036158(outer dynein arm assembly);GO:0033146(regulation of intracellular estrogen receptor signaling pathway);GO:0005813(centrosome);GO:0097730(non-motile cilium);GO:0045944(positive regulation of transcription from RNA polymerase II promoter)","NA","NA","NA","cell cycle progression 1 [Source:HGNC Symbol;Acc:HGNC:24227];DNAAF4-CCPG1 readthrough (NMD candidate) [Source:HGNC Symbol;Acc:HGNC:43019];dynein axonemal assembly factor 4 [Source:HGNC Symbol;Acc:HGNC:21493]",{"v":1.9092275628494,"d":"1.91"},{"v":9.46435692613925,"d":"9.46"},{"v":0.201728186896288,"d":"0.20"},{"v":-2.3095154132451,"d":"-2.31"},{"v":0.000877555768614181,"d":"0.00"},{"v":0.0677405549080254,"d":"0.07"},"down","yes"]
["ENSG00000173611","SCAI","ENST00000336505;ENST00000468569;ENST00000373549;ENST00000494102","GO:0006351(transcription, DNA-templated);GO:0003714(transcription corepressor activity);GO:1903507(negative regulation of nucleic acid-templated transcription);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0006355(regulation of transcription, DNA-templated);GO:0031965(nuclear membrane);GO:0005515(protein binding);GO:0005654(nucleoplasm);GO:0009968(negative regulation of signal transduction);GO:0030336(negative regulation of cell migration);GO:0035024(negative regulation of Rho protein signal transduction);GO:0035024(negative regulation of Rho protein signal transduction)","NA","NA","NA","suppressor of cancer cell invasion [Source:HGNC Symbol;Acc:HGNC:26709]",{"v":0.463450026125711,"d":"0.46"},{"v":0.0929012372829261,"d":"0.09"},{"v":4.98863136466414,"d":"4.99"},{"v":2.3186440652132,"d":"2.32"},{"v":0.000893423102547433,"d":"0.00"},{"v":0.0682222209199802,"d":"0.07"},"up","yes"]
["ENSG00000058091","CDK14","ENST00000380050;ENST00000406263;ENST00000449528;ENST00000478540;ENST00000460493","GO:0004672(protein kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0005634(nucleus);GO:0005829(cytosol);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0000166(nucleotide binding);GO:0004674(protein serine/threonine kinase activity);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0051301(cell division);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0007049(cell cycle);GO:0016055(Wnt signaling pathway);GO:0051726(regulation of cell cycle);GO:0030332(cyclin binding);GO:0000086(G2/M transition of mitotic cell cycle);GO:0004693(cyclin-dependent protein serine/threonine kinase activity);GO:0060828(regulation of canonical Wnt signaling pathway);GO:0000308(cytoplasmic cyclin-dependent protein kinase holoenzyme complex);GO:0000308(cytoplasmic cyclin-dependent protein kinase holoenzyme complex)","05202(Transcriptional misregulation in cancers);05202(Transcriptional misregulation in cancers)","K08821","EC:2.7.11.22","cyclin dependent kinase 14 [Source:HGNC Symbol;Acc:HGNC:8883]",{"v":0.557350443648589,"d":"0.56"},{"v":2.7803018573308,"d":"2.78"},{"v":0.200464004359465,"d":"0.20"},{"v":-2.31858488760466,"d":"-2.32"},{"v":0.000895126300062853,"d":"0.00"},{"v":0.0682222209199802,"d":"0.07"},"down","yes"]
["ENSG00000119121","TRPM6","ENST00000360774;ENST00000361255;ENST00000483186;ENST00000449912","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0055085(transmembrane transport);GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0004674(protein serine/threonine kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0005216(ion channel activity);GO:0006811(ion transport);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0005886(plasma membrane);GO:0006812(cation transport);GO:0006816(calcium ion transport);GO:0051262(protein tetramerization);GO:0005262(calcium channel activity);GO:0070588(calcium ion transmembrane transport);GO:0005261(cation channel activity);GO:0005515(protein binding);GO:0009636(response to toxic substance);GO:0030001(metal ion transport);GO:0016324(apical plasma membrane);GO:0031526(brush border membrane);GO:0098655(cation transmembrane transport);GO:0098655(cation transmembrane transport)","04978(Mineral absorption);04978(Mineral absorption)","K04981","EC:2.7.11.1","transient receptor potential cation channel subfamily M member 6 [Source:HGNC Symbol;Acc:HGNC:17995]",{"v":0.24625707222887,"d":"0.25"},{"v":1.25044246198194,"d":"1.25"},{"v":0.196935948447044,"d":"0.20"},{"v":-2.34420161182201,"d":"-2.34"},{"v":0.000905087295784874,"d":"0.00"},{"v":0.0685475548166129,"d":"0.07"},"down","yes"]
["ENSG00000103404","USP31","ENST00000219689;ENST00000567975","GO:0016579(protein deubiquitination);GO:0006511(ubiquitin-dependent protein catabolic process);GO:0036459(thiol-dependent ubiquitinyl hydrolase activity);GO:0016787(hydrolase activity);GO:0008233(peptidase activity);GO:0008234(cysteine-type peptidase activity);GO:0006508(proteolysis);GO:0004843(thiol-dependent ubiquitin-specific protease activity);GO:0005634(nucleus);GO:0005634(nucleus)","NA","NA","NA","ubiquitin specific peptidase 31 [Source:HGNC Symbol;Acc:HGNC:20060]",{"v":0.465828067487726,"d":"0.47"},{"v":0.093727376050595,"d":"0.09"},{"v":4.9700320985863,"d":"4.97"},{"v":2.31325516935733,"d":"2.31"},{"v":0.000949447855185741,"d":"0.00"},{"v":0.0714578192009168,"d":"0.07"},"up","yes"]
["MSTRG.4733","BTBD6","ENST00000392554;ENST00000392553;ENST00000463376;ENST00000536364","GO:0005737(cytoplasm);GO:0031625(ubiquitin protein ligase binding);GO:0000932(P-body);GO:0043161(proteasome-mediated ubiquitin-dependent protein catabolic process);GO:0005829(cytosol);GO:0043687(post-translational protein modification);GO:0030162(regulation of proteolysis);GO:0042787(protein ubiquitination involved in ubiquitin-dependent protein catabolic process);GO:0019005(SCF ubiquitin ligase complex);GO:0022008(neurogenesis);GO:0022008(neurogenesis)","NA","NA","NA","BTB domain containing 6 [Source:HGNC Symbol;Acc:HGNC:19897]",{"v":2.02133150710702,"d":"2.02"},{"v":0.402580941053512,"d":"0.40"},{"v":5.02093194431263,"d":"5.02"},{"v":2.327955170282,"d":"2.33"},{"v":0.00096078622097972,"d":"0.00"},{"v":0.0718620352362596,"d":"0.07"},"up","yes"]
["MSTRG.7543","PMAIP1","ENST00000316660;ENST00000269518;ENST00000590596","GO:0005634(nucleus);GO:0005829(cytosol);GO:0005739(mitochondrion);GO:0006915(apoptotic process);GO:0005515(protein binding);GO:0006974(cellular response to DNA damage stimulus);GO:0006919(activation of cysteine-type endopeptidase activity involved in apoptotic process);GO:0001836(release of cytochrome c from mitochondria);GO:0043065(positive regulation of apoptotic process);GO:0090200(positive regulation of release of cytochrome c from mitochondria);GO:0042981(regulation of apoptotic process);GO:2001244(positive regulation of intrinsic apoptotic signaling pathway);GO:0005741(mitochondrial outer membrane);GO:0043280(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process);GO:0097193(intrinsic apoptotic signaling pathway);GO:0032461(positive regulation of protein oligomerization);GO:0071456(cellular response to hypoxia);GO:1900740(positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway);GO:0051607(defense response to virus);GO:0042149(cellular response to glucose starvation);GO:0072332(intrinsic apoptotic signaling pathway by p53 class mediator);GO:0072593(reactive oxygen species metabolic process);GO:0043517(positive regulation of DNA damage response, signal transduction by p53 class mediator);GO:0001844(protein insertion into mitochondrial membrane involved in apoptotic signaling pathway);GO:1902237(positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway);GO:0043029(T cell homeostasis);GO:0010917(negative regulation of mitochondrial membrane potential);GO:0046902(regulation of mitochondrial membrane permeability);GO:1902043(positive regulation of extrinsic apoptotic signaling pathway via death domain receptors);GO:0010498(proteasomal protein catabolic process);GO:0010907(positive regulation of glucose metabolic process);GO:0043331(response to dsRNA);GO:0043331(response to dsRNA)","04210(Apoptosis);04215(Apoptosis - multiple species);04115(p53 signaling pathway);05200(Pathways in cancer);05203(Viral carcinogenesis);05210(Colorectal cancer);01524(Platinum drug resistance);01524(Platinum drug resistance)","K10131","NA","phorbol-12-myristate-13-acetate-induced protein 1 [Source:HGNC Symbol;Acc:HGNC:9108]",{"v":0.709960495749441,"d":"0.71"},{"v":3.6030838049217,"d":"3.60"},{"v":0.197042459789488,"d":"0.20"},{"v":-2.3434215518691,"d":"-2.34"},{"v":0.000973646375206652,"d":"0.00"},{"v":0.0723743805570278,"d":"0.07"},"down","yes"]
["MSTRG.2562","AP5B1","ENST00000532090;MSTRG.2562.1","GO:0006810(transport);GO:0015031(protein transport);GO:0005765(lysosomal membrane);GO:0005515(protein binding);GO:0016197(endosomal transport);GO:0030119(AP-type membrane coat adaptor complex)","NA","NA","NA","adaptor related protein complex 5 beta 1 subunit [Source:HGNC Symbol;Acc:HGNC:25104]",{"v":2.81910673736833,"d":"2.82"},{"v":13.7226027818247,"d":"13.72"},{"v":0.205435279457493,"d":"0.21"},{"v":-2.28324413753603,"d":"-2.28"},{"v":0.000987631741894688,"d":"0.00"},{"v":0.0729635670913855,"d":"0.07"},"down","yes"]
["MSTRG.14915","SLC31A1","ENST00000374212;ENST00000496650","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0006811(ion transport);GO:0005886(plasma membrane);GO:0005375(copper ion transmembrane transporter activity);GO:0015088(copper uptake transmembrane transporter activity);GO:0006855(drug transmembrane transport);GO:0006878(cellular copper ion homeostasis);GO:0015677(copper ion import);GO:0035434(copper ion transmembrane transport);GO:0072719(cellular response to cisplatin);GO:0098705(copper ion import across plasma membrane);GO:0005737(cytoplasm);GO:0005770(late endosome);GO:0043025(neuronal cell body);GO:0055037(recycling endosome);GO:0005887(integral component of plasma membrane);GO:0006825(copper ion transport);GO:0006825(copper ion transport)","04978(Mineral absorption);01524(Platinum drug resistance);01524(Platinum drug resistance)","K14686","NA","solute carrier family 31 member 1 [Source:HGNC Symbol;Acc:HGNC:11016]",{"v":0.701368060854301,"d":"0.70"},{"v":3.4491868710747,"d":"3.45"},{"v":0.203343015925307,"d":"0.20"},{"v":-2.2980126544338,"d":"-2.30"},{"v":0.000998008360484308,"d":"0.00"},{"v":0.07328058949361,"d":"0.07"},"down","yes"]
["MSTRG.3802","CAMKK2","MSTRG.3802.7;ENST00000412367;ENST00000392473;ENST00000542540;ENST00000545538;ENST00000539380;ENST00000544485;ENST00000347034;ENST00000535524;ENST00000324774;ENST00000543477","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0005829(cytosol);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0004713(protein tyrosine kinase activity);GO:0018108(peptidyl-tyrosine phosphorylation);GO:0042995(cell projection);GO:0045893(positive regulation of transcription, DNA-templated);GO:0005509(calcium ion binding);GO:0005516(calmodulin binding);GO:0005622(intracellular);GO:0018105(peptidyl-serine phosphorylation);GO:0000165(MAPK cascade);GO:0046777(protein autophosphorylation);GO:0045859(regulation of protein kinase activity);GO:0019722(calcium-mediated signaling);GO:0018107(peptidyl-threonine phosphorylation);GO:1903599(positive regulation of mitophagy);GO:0045860(positive regulation of protein kinase activity);GO:0001934(positive regulation of protein phosphorylation);GO:0004683(calmodulin-dependent protein kinase activity);GO:0061762(CAMKK-AMPK signaling cascade);GO:0034614(cellular response to reactive oxygen species);GO:0034614(cellular response to reactive oxygen species)","04152(AMPK signaling pathway);04140(Autophagy - animal);04920(Adipocytokine signaling pathway);04921(Oxytocin signaling pathway);04211(Longevity regulating pathway - mammal);05034(Alcoholism);05034(Alcoholism)","K07359","EC:2.7.11.17","calcium/calmodulin dependent protein kinase kinase 2 [Source:HGNC Symbol;Acc:HGNC:1470]",{"v":1.35214027037945,"d":"1.35"},{"v":6.6204728764969,"d":"6.62"},{"v":0.204236207232211,"d":"0.20"},{"v":-2.29168944334426,"d":"-2.29"},{"v":0.00101524155469387,"d":"0.00"},{"v":0.0737191769945553,"d":"0.07"},"down","yes"]
["MSTRG.3633","IKBIP","ENST00000299157;ENST00000342502;ENST00000393042","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005515(protein binding);GO:0010165(response to X-ray);GO:0010165(response to X-ray)","NA","NA","NA","IKBKB interacting protein [Source:HGNC Symbol;Acc:HGNC:26430]",{"v":0.886498697333654,"d":"0.89"},{"v":4.35245864616863,"d":"4.35"},{"v":0.203677684132397,"d":"0.20"},{"v":-2.29564017425551,"d":"-2.30"},{"v":0.00102032651838535,"d":"0.00"},{"v":0.0737191769945553,"d":"0.07"},"down","yes"]
["ENSG00000180667","YOD1","ENST00000315927;ENST00000367084","GO:0003676(nucleic acid binding);GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0016787(hydrolase activity);GO:0008233(peptidase activity);GO:0008234(cysteine-type peptidase activity);GO:0006508(proteolysis);GO:0036459(thiol-dependent ubiquitinyl hydrolase activity);GO:0005634(nucleus);GO:0005515(protein binding);GO:0006986(response to unfolded protein);GO:0005829(cytosol);GO:0016579(protein deubiquitination);GO:0004843(thiol-dependent ubiquitin-specific protease activity);GO:0070536(protein K63-linked deubiquitination);GO:0071108(protein K48-linked deubiquitination);GO:0030433(ubiquitin-dependent ERAD pathway);GO:0031625(ubiquitin protein ligase binding);GO:0030968(endoplasmic reticulum unfolded protein response);GO:0035871(protein K11-linked deubiquitination);GO:0061578(Lys63-specific deubiquitinase activity);GO:1990380(Lys48-specific deubiquitinase activity);GO:0016236(macroautophagy);GO:1904265(ubiquitin-specific protease activity involved in negative regulation of retrograde protein transport, ER to cytosol);GO:0035523(protein K29-linked deubiquitination);GO:1904153(negative regulation of retrograde protein transport, ER to cytosol);GO:1990167(protein K27-linked deubiquitination);GO:1990168(protein K33-linked deubiquitination);GO:1990168(protein K33-linked deubiquitination)","04141(Protein processing in endoplasmic reticulum);04141(Protein processing in endoplasmic reticulum)","K13719","EC:3.1.2.-","YOD1 deubiquitinase [Source:HGNC Symbol;Acc:HGNC:25035]",{"v":1.65893280171753,"d":"1.66"},{"v":0.345906258856004,"d":"0.35"},{"v":4.79590281830697,"d":"4.80"},{"v":2.26180242502255,"d":"2.26"},{"v":0.00102803750745418,"d":"0.00"},{"v":0.0737191769945553,"d":"0.07"},"up","yes"]
["ENSG00000178445","GLDC","ENST00000321612;ENST00000639493;ENST00000640703;ENST00000640592;ENST00000639639","GO:0005634(nucleus);GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0005739(mitochondrion);GO:0003824(catalytic activity);GO:0005886(plasma membrane);GO:0042803(protein homodimerization activity);GO:0006546(glycine catabolic process);GO:0006520(cellular amino acid metabolic process);GO:0016829(lyase activity);GO:0004375(glycine dehydrogenase (decarboxylating) activity);GO:0005759(mitochondrial matrix);GO:0009055(electron carrier activity);GO:0016594(glycine binding);GO:0019899(enzyme binding);GO:0030170(pyridoxal phosphate binding);GO:0046983(protein dimerization activity);GO:0070280(pyridoxal binding);GO:0006544(glycine metabolic process);GO:0019464(glycine decarboxylation via glycine cleavage system);GO:0036255(response to methylamine);GO:1903442(response to lipoic acid);GO:1990830(cellular response to leukemia inhibitory factor);GO:0005960(glycine cleavage complex);GO:0005960(glycine cleavage complex)","00630(Glyoxylate and dicarboxylate metabolism);00260(Glycine, serine and threonine metabolism);00260(Glycine, serine and threonine metabolism)","K00281","EC:1.4.4.2","glycine decarboxylase [Source:HGNC Symbol;Acc:HGNC:4313]",{"v":0.38805832553977,"d":"0.39"},{"v":0.0758620463139054,"d":"0.08"},{"v":5.11531581858529,"d":"5.12"},{"v":2.35482331442638,"d":"2.35"},{"v":0.00102846883699429,"d":"0.00"},{"v":0.0737191769945553,"d":"0.07"},"up","yes"]
["ENSG00000148450","MSRB2","ENST00000376510;ENST00000468633;ENST00000472663","GO:0046872(metal ion binding);GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0003779(actin binding);GO:0005739(mitochondrion);GO:0006355(regulation of transcription, DNA-templated);GO:0006979(response to oxidative stress);GO:0016671(oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor);GO:0033743(peptide-methionine (R)-S-oxide reductase activity);GO:0030091(protein repair);GO:0005829(cytosol);GO:0030041(actin filament polymerization);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0008270(zinc ion binding);GO:0008270(zinc ion binding)","NA","NA","NA","methionine sulfoxide reductase B2 [Source:HGNC Symbol;Acc:HGNC:17061]",{"v":0.81820059502924,"d":"0.82"},{"v":4.10649009356725,"d":"4.11"},{"v":0.199245724788412,"d":"0.20"},{"v":-2.32737932621856,"d":"-2.33"},{"v":1.0552988254722E-3,"d":"0.00"},{"v":0.0751646848251081,"d":"0.08"},"down","yes"]
["ENSG00000149573","MPZL2","ENST00000278937;ENST00000438295;ENST00000527282;ENST00000529376;ENST00000528554","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0007155(cell adhesion);GO:0005515(protein binding);GO:0016337(single organismal cell-cell adhesion);GO:0005856(cytoskeleton);GO:0009653(anatomical structure morphogenesis);GO:0007156(homophilic cell adhesion via plasma membrane adhesion molecules);GO:0007156(homophilic cell adhesion via plasma membrane adhesion molecules)","NA","NA","NA","myelin protein zero like 2 [Source:HGNC Symbol;Acc:HGNC:3496]",{"v":0.395935079528719,"d":"0.40"},{"v":1.99976834735956,"d":"2.00"},{"v":0.197990472272201,"d":"0.20"},{"v":-2.33649708850356,"d":"-2.34"},{"v":1.06111911810898E-3,"d":"0.00"},{"v":0.0751646848251081,"d":"0.08"},"down","yes"]
["MSTRG.5016","HAUS2","ENST00000563479;ENST00000568846;ENST00000562398;ENST00000568876;ENST00000391623;ENST00000607467;ENST00000564279;ENST00000260372","GO:0005737(cytoplasm);GO:0051301(cell division);GO:0005856(cytoskeleton);GO:0007049(cell cycle);GO:0005874(microtubule);GO:0007098(centrosome cycle);GO:0031023(microtubule organizing center organization);GO:0051225(spindle assembly);GO:0005876(spindle microtubule);GO:0070652(HAUS complex);GO:0005813(centrosome);GO:0005815(microtubule organizing center);GO:0005819(spindle);GO:0003674(molecular_function);GO:0005829(cytosol);GO:0000086(G2/M transition of mitotic cell cycle);GO:0010389(regulation of G2/M transition of mitotic cell cycle);GO:0097711(ciliary basal body docking);GO:0097711(ciliary basal body docking)","NA","NA","NA","HAUS augmin like complex subunit 2 [Source:HGNC Symbol;Acc:HGNC:25530]",{"v":1.27595304765209,"d":"1.28"},{"v":0.260261441360167,"d":"0.26"},{"v":4.90258196136838,"d":"4.90"},{"v":2.29354174959566,"d":"2.29"},{"v":1.12806805857189E-3,"d":"0.00"},{"v":0.079218031412381,"d":"0.08"},"up","yes"]
["ENSG00000197779","ZNF81","ENST00000376950;ENST00000376954;ENST00000334937;ENST00000483520;ENST00000338637","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0005622(intracellular);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding)","NA","NA","NA","zinc finger protein 81 [Source:HGNC Symbol;Acc:HGNC:13156]",{"v":0.484002274073197,"d":"0.48"},{"v":0.0958086821035177,"d":"0.10"},{"v":5.05175797690496,"d":"5.05"},{"v":2.33678552315498,"d":"2.34"},{"v":0.0011314982065213,"d":"0.00"},{"v":0.079218031412381,"d":"0.08"},"up","yes"]
["MSTRG.7693","SH3GL1","ENST00000269886;ENST00000593591","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0042995(cell projection);GO:0005515(protein binding);GO:0045202(synapse);GO:0030054(cell junction);GO:0042802(identical protein binding);GO:0008289(lipid binding);GO:0005768(endosome);GO:0045296(cadherin binding);GO:0006897(endocytosis);GO:0002102(podosome);GO:0031901(early endosome membrane);GO:0007165(signal transduction);GO:0007417(central nervous system development);GO:0019902(phosphatase binding);GO:0051020(GTPase binding);GO:0016191(synaptic vesicle uncoating);GO:0016191(synaptic vesicle uncoating)","04144(Endocytosis);04144(Endocytosis)","K11247","NA","SH3 domain containing GRB2 like 1, endophilin A2 [Source:HGNC Symbol;Acc:HGNC:10830]",{"v":1.99522478914518,"d":"2.00"},{"v":9.49467781709633,"d":"9.49"},{"v":0.210141389479539,"d":"0.21"},{"v":-2.25056775145799,"d":"-2.25"},{"v":0.00119685863229046,"d":"0.00"},{"v":0.0833096627170041,"d":"0.08"},"down","yes"]
["MSTRG.4749","IGHA1;IGHG2;IGHG1;IGHM;IGHG3;IGHA2;IGHD3-3;IGHJ4;AL928742.1","MSTRG.4749.13;MSTRG.4749.10;MSTRG.4749.20;ENST00000390549;ENST00000390545;ENST00000390547;MSTRG.4749.15;ENST00000390559;ENST00000637539;ENST00000390551;MSTRG.4749.12;MSTRG.4749.7;MSTRG.4749.2;MSTRG.4749.26;MSTRG.4749.4;ENST00000390539;MSTRG.4749.29;ENST00000641136;MSTRG.4749.27;ENST00000390548;MSTRG.4749.28;ENST00000641837;MSTRG.4749.9;ENST00000641095;MSTRG.4749.18;MSTRG.4749.21;ENST00000390590;ENST00000461719;ENST00000497397;MSTRG.4749.16;MSTRG.4749.30;ENST00000497872;MSTRG.4749.6;ENST00000390542","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0006508(proteolysis);GO:0005615(extracellular space);GO:0002376(immune system process);GO:0003823(antigen binding);GO:0002250(adaptive immune response);GO:0004252(serine-type endopeptidase activity);GO:0006956(complement activation);GO:0006958(complement activation, classical pathway);GO:0030449(regulation of complement activation);GO:0038096(Fc-gamma receptor signaling pathway involved in phagocytosis);GO:0034987(immunoglobulin receptor binding);GO:0006910(phagocytosis, recognition);GO:0006911(phagocytosis, engulfment);GO:0042742(defense response to bacterium);GO:0045087(innate immune response);GO:0050853(B cell receptor signaling pathway);GO:0050871(positive regulation of B cell activation);GO:0009897(external side of plasma membrane);GO:0042571(immunoglobulin complex, circulating);GO:0070062(extracellular exosome);GO:0072562(blood microparticle);GO:0006955(immune response);GO:0006898(receptor-mediated endocytosis);GO:0050900(leukocyte migration);GO:0018298(protein-chromophore linkage);GO:0001895(retina homeostasis);GO:0019731(antibacterial humoral response);GO:0003094(glomerular filtration);GO:0060267(positive regulation of respiratory burst);GO:0071748(monomeric IgA immunoglobulin complex);GO:0071751(secretory IgA immunoglobulin complex);GO:0071752(secretory dimeric IgA immunoglobulin complex);GO:0031210(phosphatidylcholine binding);GO:0050829(defense response to Gram-negative bacterium);GO:0009986(cell surface);GO:0003697(single-stranded DNA binding);GO:0042834(peptidoglycan binding);GO:0071756(pentameric IgM immunoglobulin complex);GO:0071757(hexameric IgM immunoglobulin complex);GO:0072562(blood microparticle)","NA","NA","NA","immunoglobulin heavy constant gamma 1 (G1m marker) [Source:HGNC Symbol;Acc:HGNC:5525];immunoglobulin heavy constant gamma 2 (G2m marker) [Source:HGNC Symbol;Acc:HGNC:5526];immunoglobulin heavy constant alpha 1 [Source:HGNC Symbol;Acc:HGNC:5478];immunoglobulin heavy constant mu [Source:HGNC Symbol;Acc:HGNC:5541];immunoglobulin heavy constant gamma 3 (G3m marker) [Source:HGNC Symbol;Acc:HGNC:5527];immunoglobulin heavy constant alpha 2 (A2m marker) [Source:HGNC Symbol;Acc:HGNC:5479];immunoglobulin heavy diversity 3-3 [Source:HGNC Symbol;Acc:HGNC:5498];immunoglobulin heavy joining 4 [Source:HGNC Symbol;Acc:HGNC:5538]",{"v":208.065977551854,"d":"208.07"},{"v":45.8198373725479,"d":"45.82"},{"v":4.54095844688687,"d":"4.54"},{"v":2.18299683510082,"d":"2.18"},{"v":0.00120899617860078,"d":"0.00"},{"v":0.0836708734638537,"d":"0.08"},"up","yes"]
["MSTRG.14925","TNFSF8","ENST00000618336;MSTRG.14925.2;ENST00000223795","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0006955(immune response);GO:0005125(cytokine activity);GO:0005615(extracellular space);GO:0005164(tumor necrosis factor receptor binding);GO:0005886(plasma membrane);GO:0033209(tumor necrosis factor-mediated signaling pathway);GO:0005887(integral component of plasma membrane);GO:0007165(signal transduction);GO:0007267(cell-cell signaling);GO:0006915(apoptotic process);GO:0005102(receptor binding);GO:0008283(cell proliferation);GO:0043374(CD8-positive, alpha-beta T cell differentiation);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0050830(defense response to Gram-positive bacterium);GO:0050830(defense response to Gram-positive bacterium)","04060(Cytokine-cytokine receptor interaction);04060(Cytokine-cytokine receptor interaction)","K05471","NA","TNF superfamily member 8 [Source:HGNC Symbol;Acc:HGNC:11938]",{"v":3.95666313685216,"d":"3.96"},{"v":0.860209935275854,"d":"0.86"},{"v":4.5996482656101,"d":"4.60"},{"v":2.20152354272146,"d":"2.20"},{"v":0.00124767126994072,"d":"0.00"},{"v":0.0858540424721493,"d":"0.09"},"up","yes"]
["MSTRG.4738","IGHV1-3","ENST00000390595","GO:0016020(membrane);GO:0005886(plasma membrane);GO:0005576(extracellular region);GO:0002376(immune system process);GO:0003823(antigen binding);GO:0002250(adaptive immune response);GO:0034987(immunoglobulin receptor binding);GO:0006910(phagocytosis, recognition);GO:0006911(phagocytosis, engulfment);GO:0006958(complement activation, classical pathway);GO:0042742(defense response to bacterium);GO:0045087(innate immune response);GO:0050853(B cell receptor signaling pathway);GO:0050871(positive regulation of B cell activation);GO:0009897(external side of plasma membrane);GO:0042571(immunoglobulin complex, circulating);GO:0072562(blood microparticle)","NA","NA","NA","immunoglobulin heavy variable 1-3 [Source:HGNC Symbol;Acc:HGNC:5552]",{"v":13.929519,"d":"13.93"},{"v":2.969171,"d":"2.97"},{"v":4.6913832177399,"d":"4.69"},{"v":2.23001335283811,"d":"2.23"},{"v":0.00131125535935697,"d":"0.00"},{"v":0.0897166877123674,"d":"0.09"},"up","yes"]
["ENSG00000261609","GAN","ENST00000568107","GO:0005737(cytoplasm);GO:0016567(protein ubiquitination);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0007010(cytoskeleton organization);GO:0004842(ubiquitin-protein transferase activity);GO:0003674(molecular_function);GO:0005829(cytosol);GO:0043687(post-translational protein modification);GO:0031463(Cul3-RING ubiquitin ligase complex)","NA","NA","NA","gigaxonin [Source:HGNC Symbol;Acc:HGNC:4137]",{"v":0.0472132584707257,"d":"0.05"},{"v":0.235650708814748,"d":"0.24"},{"v":0.200352711469421,"d":"0.20"},{"v":-2.319386060302,"d":"-2.32"},{"v":0.00134024906125237,"d":"0.00"},{"v":0.0911823683367294,"d":"0.09"},"down","yes"]
["MSTRG.5917","NOD2","MSTRG.5917.1;ENST00000534057;ENST00000524712;ENST00000527070;ENST00000532206;ENST00000534067;ENST00000526417;ENST00000641284;MSTRG.5917.8;ENST00000527052;ENST00000531674","GO:0042981(regulation of apoptotic process);GO:0070374(positive regulation of ERK1 and ERK2 cascade);GO:0032755(positive regulation of interleukin-6 production);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005794(Golgi apparatus);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0005829(cytosol);GO:0003779(actin binding);GO:0005886(plasma membrane);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0002376(immune system process);GO:0045087(innate immune response);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0019901(protein kinase binding);GO:0050700(CARD domain binding);GO:0070431(nucleotide-binding oligomerization domain containing 2 signaling pathway);GO:0008180(COP9 signalosome);GO:0016579(protein deubiquitination);GO:0016323(basolateral plasma membrane);GO:0043234(protein complex);GO:0043123(positive regulation of I-kappaB kinase/NF-kappaB signaling);GO:0019899(enzyme binding);GO:0051092(positive regulation of NF-kappaB transcription factor activity);GO:0032733(positive regulation of interleukin-10 production);GO:0032760(positive regulation of tumor necrosis factor production);GO:0051770(positive regulation of nitric-oxide synthase biosynthetic process);GO:0009986(cell surface);GO:0031982(vesicle);GO:0002606(positive regulation of dendritic cell antigen processing and presentation);GO:0043552(positive regulation of phosphatidylinositol 3-kinase activity);GO:0007254(JNK cascade);GO:0070423(nucleotide-binding oligomerization domain containing signaling pathway);GO:0000187(activation of MAPK activity);GO:0071225(cellular response to muramyl dipeptide);GO:0035556(intracellular signal transduction);GO:1901224(positive regulation of NIK/NF-kappaB signaling);GO:0002374(cytokine secretion involved in immune response);GO:0050727(regulation of inflammatory response);GO:0051879(Hsp90 protein binding);GO:0051353(positive regulation of oxidoreductase activity);GO:0030277(maintenance of gastrointestinal epithelium);GO:0050679(positive regulation of epithelial cell proliferation);GO:0032757(positive regulation of interleukin-8 production);GO:0045747(positive regulation of Notch signaling pathway);GO:0032731(positive regulation of interleukin-1 beta production);GO:0050871(positive regulation of B cell activation);GO:0060585(positive regulation of prostaglandin-endoperoxide synthase activity);GO:0030544(Hsp70 protein binding);GO:0002830(positive regulation of type 2 immune response);GO:0046330(positive regulation of JNK cascade);GO:0035419(activation of MAPK activity involved in innate immune response);GO:0032740(positive regulation of interleukin-17 production);GO:1902523(positive regulation of protein K63-linked ubiquitination);GO:0032495(response to muramyl dipeptide);GO:0002367(cytokine production involved in immune response);GO:0050718(positive regulation of interleukin-1 beta secretion);GO:0042834(peptidoglycan binding);GO:0006952(defense response);GO:0009595(detection of biotic stimulus);GO:0051259(protein oligomerization);GO:2000110(negative regulation of macrophage apoptotic process);GO:0032874(positive regulation of stress-activated MAPK cascade);GO:0032500(muramyl dipeptide binding);GO:0002732(positive regulation of dendritic cell cytokine production);GO:0007584(response to nutrient);GO:0008284(positive regulation of cell proliferation);GO:0016045(detection of bacterium);GO:0032498(detection of muramyl dipeptide);GO:0042742(defense response to bacterium);GO:0046645(positive regulation of gamma-delta T cell activation);GO:0071407(cellular response to organic cyclic compound);GO:1900017(positive regulation of cytokine production involved in inflammatory response);GO:2000363(positive regulation of prostaglandin-E synthase activity);GO:2000363(positive regulation of prostaglandin-E synthase activity)","04668(TNF signaling pathway);04621(NOD-like receptor signaling pathway);05321(Inflammatiory bowel disease (IBD));05131(Shigellosis);05152(Tuberculosis);05152(Tuberculosis)","K10165","NA","nucleotide binding oligomerization domain containing 2 [Source:HGNC Symbol;Acc:HGNC:5331]",{"v":1.55802505411255,"d":"1.56"},{"v":7.23082698051948,"d":"7.23"},{"v":0.215469829150941,"d":"0.22"},{"v":-2.21444222270338,"d":"-2.21"},{"v":0.00139800375205427,"d":"0.00"},{"v":0.0945773100125703,"d":"0.09"},"down","yes"]
["MSTRG.8449","CCDC106;ZNF580;ZNF581","ENST00000308964;ENST00000543039;ENST00000587252;ENST00000592881;ENST00000592996;ENST00000586864;ENST00000588537;ENST00000591578;ENST00000590190;ENST00000588740;ENST00000593069;ENST00000325333;ENST00000586790;ENST00000270451","GO:0005634(nucleus);GO:0005829(cytosol);GO:0005515(protein binding);GO:0003676(nucleic acid binding);GO:0046872(metal ion binding);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0006935(chemotaxis);GO:0006954(inflammatory response);GO:0010628(positive regulation of gene expression);GO:0010595(positive regulation of endothelial cell migration);GO:0001938(positive regulation of endothelial cell proliferation);GO:0070301(cellular response to hydrogen peroxide);GO:0032757(positive regulation of interleukin-8 production);GO:0002690(positive regulation of leukocyte chemotaxis);GO:0005515(protein binding)","NA","NA","NA","coiled-coil domain containing 106 [Source:HGNC Symbol;Acc:HGNC:30181];zinc finger protein 580 [Source:HGNC Symbol;Acc:HGNC:29473];zinc finger protein 581 [Source:HGNC Symbol;Acc:HGNC:25017]",{"v":2.03434087726998,"d":"2.03"},{"v":0.447298017857143,"d":"0.45"},{"v":4.54806593379473,"d":"4.55"},{"v":2.18525316928495,"d":"2.19"},{"v":1.42415461727917E-3,"d":"0.00"},{"v":0.0958082117389711,"d":"0.10"},"up","yes"]
["ENSG00000163599","CTLA4","ENST00000302823;ENST00000295854","GO:0048471(perinuclear region of cytoplasm);GO:0045590(negative regulation of regulatory T cell differentiation);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0006974(cellular response to DNA damage stimulus);GO:0006955(immune response);GO:0002376(immune system process);GO:0002250(adaptive immune response);GO:0005887(integral component of plasma membrane);GO:0043065(positive regulation of apoptotic process);GO:0009897(external side of plasma membrane);GO:0050853(B cell receptor signaling pathway);GO:0031295(T cell costimulation);GO:0005794(Golgi apparatus);GO:0030889(negative regulation of B cell proliferation);GO:0045589(regulation of regulatory T cell differentiation);GO:0098636(protein complex involved in cell adhesion);GO:0042130(negative regulation of T cell proliferation);GO:0050777(negative regulation of immune response);GO:0045334(clathrin-coated endocytic vesicle);GO:0045334(clathrin-coated endocytic vesicle)","04514(Cell adhesion molecules (CAMs));04660(T cell receptor signaling pathway);05323(Rheumatoid arthritis);05320(Autoimmune thyroid disease);05320(Autoimmune thyroid disease)","K06538","NA","cytotoxic T-lymphocyte associated protein 4 [Source:HGNC Symbol;Acc:HGNC:2505]",{"v":1.74332326273585,"d":"1.74"},{"v":0.368003629245283,"d":"0.37"},{"v":4.73724475574094,"d":"4.74"},{"v":2.24404821250863,"d":"2.24"},{"v":0.00145060443136797,"d":"0.00"},{"v":0.096634917331395,"d":"0.10"},"up","yes"]
["ENSG00000139832","RAB20","ENST00000267328","GO:0006810(transport);GO:0016020(membrane);GO:0015031(protein transport);GO:0005794(Golgi apparatus);GO:0043231(intracellular membrane-bounded organelle);GO:0005525(GTP binding);GO:0000166(nucleotide binding);GO:0003924(GTPase activity);GO:0031410(cytoplasmic vesicle);GO:0005886(plasma membrane);GO:0030670(phagocytic vesicle membrane);GO:0030100(regulation of endocytosis);GO:0005769(early endosome);GO:0090385(phagosome-lysosome fusion);GO:0045335(phagocytic vesicle);GO:0090383(phagosome acidification)","NA","NA","NA","RAB20, member RAS oncogene family [Source:HGNC Symbol;Acc:HGNC:18260]",{"v":0.95964,"d":"0.96"},{"v":4.573757,"d":"4.57"},{"v":0.209814382355687,"d":"0.21"},{"v":-2.25281451972697,"d":"-2.25"},{"v":1.4541589637787E-3,"d":"0.00"},{"v":0.096634917331395,"d":"0.10"},"down","yes"]
["ENSG00000198521","ZNF43","ENST00000599906;ENST00000594012;ENST00000598288;ENST00000357491;ENST00000593886;ENST00000599414;ENST00000354959","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0005622(intracellular);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding)","NA","NA","NA","zinc finger protein 43 [Source:HGNC Symbol;Acc:HGNC:13109]",{"v":0.656919114926581,"d":"0.66"},{"v":0.138786124291826,"d":"0.14"},{"v":4.73331983495177,"d":"4.73"},{"v":2.24285240965477,"d":"2.24"},{"v":0.0014639781425446,"d":"0.00"},{"v":0.096634917331395,"d":"0.10"},"up","yes"]
["ENSG00000106714","CNTNAP3","ENST00000297668;ENST00000443583;ENST00000358144;ENST00000493965;ENST00000477002;ENST00000469061;ENST00000377653;ENST00000377656;ENST00000483502;ENST00000377659","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0007155(cell adhesion);GO:0005886(plasma membrane);GO:0005576(extracellular region);GO:0008037(cell recognition);GO:0008037(cell recognition)","NA","NA","NA","contactin associated protein like 3 [Source:HGNC Symbol;Acc:HGNC:13834]",{"v":0.332807911143787,"d":"0.33"},{"v":1.56437975181178,"d":"1.56"},{"v":0.212741126800156,"d":"0.21"},{"v":-2.23282913495437,"d":"-2.23"},{"v":0.00147027799015778,"d":"0.00"},{"v":0.096634917331395,"d":"0.10"},"down","yes"]
["ENSG00000152213","ARL11","ENST00000282026;ENST00000490932","GO:0005525(GTP binding);GO:0007264(small GTPase mediated signal transduction);GO:0000166(nucleotide binding);GO:0005622(intracellular);GO:0005515(protein binding);GO:0005515(protein binding)","NA","NA","NA","ADP ribosylation factor like GTPase 11 [Source:HGNC Symbol;Acc:HGNC:24046]",{"v":2.06979500575013,"d":"2.07"},{"v":0.453202638787245,"d":"0.45"},{"v":4.56704094064596,"d":"4.57"},{"v":2.19125972262675,"d":"2.19"},{"v":1.47656741313542E-3,"d":"0.00"},{"v":0.096634917331395,"d":"0.10"},"up","yes"]
["MSTRG.12547","CPEB4","ENST00000265085;ENST00000518141;ENST00000519467;MSTRG.12547.2;ENST00000519835;ENST00000519152;ENST00000520867;ENST00000334035","GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0046872(metal ion binding);GO:0005783(endoplasmic reticulum);GO:0005886(plasma membrane);GO:0042995(cell projection);GO:0005515(protein binding);GO:0003730(mRNA 3'-UTR binding);GO:0045182(translation regulator activity);GO:0006417(regulation of translation);GO:0048471(perinuclear region of cytoplasm);GO:0030054(cell junction);GO:0045202(synapse);GO:0045211(postsynaptic membrane);GO:0030425(dendrite);GO:0071230(cellular response to amino acid stimulus);GO:0030424(axon);GO:0030426(growth cone);GO:0014069(postsynaptic density);GO:0043197(dendritic spine);GO:0000900(translation repressor activity, nucleic acid binding);GO:0008135(translation factor activity, RNA binding);GO:0043022(ribosome binding);GO:2000766(negative regulation of cytoplasmic translation);GO:0043005(neuron projection);GO:1990124(messenger ribonucleoprotein complex);GO:0043524(negative regulation of neuron apoptotic process);GO:0002931(response to ischemia);GO:0042149(cellular response to glucose starvation);GO:0035235(ionotropic glutamate receptor signaling pathway);GO:0006412(translation);GO:0036294(cellular response to decreased oxygen levels);GO:0036294(cellular response to decreased oxygen levels)","04114(Oocyte meiosis);04914(Progesterone-mediated oocyte maturation);04914(Progesterone-mediated oocyte maturation)","K02602","NA","cytoplasmic polyadenylation element binding protein 4 [Source:HGNC Symbol;Acc:HGNC:21747]",{"v":1.13267081415498,"d":"1.13"},{"v":5.178266144081,"d":"5.18"},{"v":0.218735534759965,"d":"0.22"},{"v":-2.19274048191996,"d":"-2.19"},{"v":1.52901122277204E-3,"d":"0.00"},{"v":0.099526233214167,"d":"0.10"},"down","yes"]
["MSTRG.12242","CAMK4","ENST00000282356;ENST00000512453;ENST00000509408;ENST00000509645;ENST00000515231","GO:0004672(protein kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0000166(nucleotide binding);GO:0004674(protein serine/threonine kinase activity);GO:0005654(nucleoplasm);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0001650(fibrillar center);GO:0045893(positive regulation of transcription, DNA-templated);GO:0002376(immune system process);GO:0006954(inflammatory response);GO:0002250(adaptive immune response);GO:0005516(calmodulin binding);GO:0035556(intracellular signal transduction);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0007616(long-term memory);GO:0018105(peptidyl-serine phosphorylation);GO:0007165(signal transduction);GO:0043011(myeloid dendritic cell differentiation);GO:0033081(regulation of T cell differentiation in thymus);GO:0045670(regulation of osteoclast differentiation);GO:0009931(calcium-dependent protein serine/threonine kinase activity);GO:0046777(protein autophosphorylation);GO:0004683(calmodulin-dependent protein kinase activity);GO:0004683(calmodulin-dependent protein kinase activity)","04371(Apelin signaling pathway);04020(Calcium signaling pathway);04024(cAMP signaling pathway);04921(Oxytocin signaling pathway);04925(Aldosterone synthesis and secretion);04725(Cholinergic synapse);04720(Long-term potentiation);04722(Neurotrophin signaling pathway);04380(Osteoclast differentiation);04211(Longevity regulating pathway - mammal);05031(Amphetamine addiction);05034(Alcoholism);05034(Alcoholism)","K05869","EC:2.7.11.17","calcium/calmodulin dependent protein kinase IV [Source:HGNC Symbol;Acc:HGNC:1464]",{"v":3.20610339036664,"d":"3.21"},{"v":0.725273329115744,"d":"0.73"},{"v":4.42054500235867,"d":"4.42"},{"v":2.14422424828842,"d":"2.14"},{"v":1.53836093695382E-3,"d":"0.00"},{"v":0.0995964645311715,"d":"0.10"},"up","yes"]
["MSTRG.8934","IGKV1-16;IGKV3-15;IGKV1-5;IGKC;IGKV1-39;IGKV3-20;AC244205.1;IGKV1-12;IGKJ4;IGKV2-30;IGKV1-33;IGKJ5;IGKJ2;IGKV6-21;IGKV2-29;IGKJ3;AC244205.2;IGKV1-13","MSTRG.8934.12;ENST00000390252;ENST00000496168;ENST00000390237;MSTRG.8934.26;MSTRG.8934.17;ENST00000492167;MSTRG.8934.23;MSTRG.8934.6;MSTRG.8934.5;MSTRG.8934.15;MSTRG.8934.13;ENST00000480492;MSTRG.8934.21;ENST00000390239;MSTRG.8934.24;ENST00000624935;ENST00000468494;ENST00000473726;MSTRG.8934.27;ENST00000498574;ENST00000390238;ENST00000479981;ENST00000390241;MSTRG.8934.11;MSTRG.8934.29;MSTRG.8934.9;MSTRG.8934.7;ENST00000521304;MSTRG.8934.10;MSTRG.8934.14;MSTRG.8934.18;MSTRG.8934.16;ENST00000390240;MSTRG.8934.19;ENST00000390256;MSTRG.8934.28;MSTRG.8934.8;MSTRG.8934.25;ENST00000434790;MSTRG.8934.20;ENST00000635781;MSTRG.8934.22;MSTRG.8934.4","GO:0016020(membrane);GO:0005886(plasma membrane);GO:0005576(extracellular region);GO:0006508(proteolysis);GO:0006955(immune response);GO:0002376(immune system process);GO:0003823(antigen binding);GO:0002250(adaptive immune response);GO:0004252(serine-type endopeptidase activity);GO:0006898(receptor-mediated endocytosis);GO:0006956(complement activation);GO:0006958(complement activation, classical pathway);GO:0030449(regulation of complement activation);GO:0038095(Fc-epsilon receptor signaling pathway);GO:0038096(Fc-gamma receptor signaling pathway involved in phagocytosis);GO:0050776(regulation of immune response);GO:0050900(leukocyte migration);GO:0070062(extracellular exosome);GO:0072562(blood microparticle);GO:0002377(immunoglobulin production);GO:0005615(extracellular space);GO:0019731(antibacterial humoral response);GO:0003094(glomerular filtration);GO:0071748(monomeric IgA immunoglobulin complex);GO:0071751(secretory IgA immunoglobulin complex);GO:0071756(pentameric IgM immunoglobulin complex);GO:0002250(adaptive immune response)","NA","NA","NA","immunoglobulin kappa variable 3-15 [Source:HGNC Symbol;Acc:HGNC:5816];immunoglobulin kappa variable 1-5 [Source:HGNC Symbol;Acc:HGNC:5741];immunoglobulin kappa constant [Source:HGNC Symbol;Acc:HGNC:5716];immunoglobulin kappa variable 3-20 [Source:HGNC Symbol;Acc:HGNC:5817];immunoglobulin kappa variable 1-12 [Source:HGNC Symbol;Acc:HGNC:5730];immunoglobulin kappa joining 4 [Source:HGNC Symbol;Acc:HGNC:5722];immunoglobulin kappa variable 2-30 [Source:HGNC Symbol;Acc:HGNC:5785];immunoglobulin kappa variable 1-33 [Source:HGNC Symbol;Acc:HGNC:5737];immunoglobulin kappa variable 1-39 (gene/pseudogene) [Source:HGNC Symbol;Acc:HGNC:5740];immunoglobulin kappa joining 5 [Source:HGNC Symbol;Acc:HGNC:5723];immunoglobulin kappa variable 1-16 [Source:HGNC Symbol;Acc:HGNC:5732];immunoglobulin kappa joining 2 [Source:HGNC Symbol;Acc:HGNC:5720];immunoglobulin kappa variable 2-29 (gene/pseudogene) [Source:HGNC Symbol;Acc:HGNC:5784];immunoglobulin kappa joining 3 [Source:HGNC Symbol;Acc:HGNC:5721];immunoglobulin kappa variable 6-21 (non-functional) [Source:HGNC Symbol;Acc:HGNC:5836]",{"v":85.4273601628664,"d":"85.43"},{"v":19.5201734131143,"d":"19.52"},{"v":4.37636276865622,"d":"4.38"},{"v":2.12973233201739,"d":"2.13"},{"v":1.56024900073076E-3,"d":"0.00"},{"v":0.100473360785025,"d":"0.10"},"up","yes"]
["ENSG00000116199","FAM20B","ENST00000263733;ENST00000440702","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005794(Golgi apparatus);GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0005654(nucleoplasm);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0005515(protein binding);GO:0000139(Golgi membrane);GO:0005615(extracellular space);GO:1903955(positive regulation of protein targeting to mitochondrion);GO:0016773(phosphotransferase activity, alcohol group as acceptor);GO:0016773(phosphotransferase activity, alcohol group as acceptor)","NA","NA","NA","FAM20B, glycosaminoglycan xylosylkinase [Source:HGNC Symbol;Acc:HGNC:23017]",{"v":0.574730921841365,"d":"0.57"},{"v":2.64624489617486,"d":"2.65"},{"v":0.217187352036895,"d":"0.22"},{"v":-2.20298800502756,"d":"-2.20"},{"v":0.00157768388659625,"d":"0.00"},{"v":0.10105568809783,"d":"0.10"},"down","yes"]
["ENSG00000198625","MDM4","ENST00000367182;ENST00000391947;ENST00000470797;ENST00000367183;ENST00000462012;ENST00000367179;ENST00000463049;ENST00000470908;ENST00000367180;ENST00000454264","GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0043066(negative regulation of apoptotic process);GO:0016567(protein ubiquitination);GO:0008270(zinc ion binding);GO:0005515(protein binding);GO:0071157(negative regulation of cell cycle arrest);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0061630(ubiquitin protein ligase activity);GO:0006977(DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest);GO:0005654(nucleoplasm);GO:0050821(protein stabilization);GO:0016579(protein deubiquitination);GO:0008283(cell proliferation);GO:0019899(enzyme binding);GO:1901796(regulation of signal transduction by p53 class mediator);GO:0008285(negative regulation of cell proliferation);GO:0042177(negative regulation of protein catabolic process);GO:0006461(protein complex assembly);GO:0030330(DNA damage response, signal transduction by p53 class mediator);GO:0045023(G0 to G1 transition);GO:0071456(cellular response to hypoxia);GO:0071456(cellular response to hypoxia)","04115(p53 signaling pathway);05206(MicroRNAs in cancer);05206(MicroRNAs in cancer)","K10127","NA","MDM4, p53 regulator [Source:HGNC Symbol;Acc:HGNC:6974]",{"v":0.56415227734375,"d":"0.56"},{"v":2.59017174945494,"d":"2.59"},{"v":0.217804968903111,"d":"0.22"},{"v":-2.19889122747118,"d":"-2.20"},{"v":1.58826992479575E-3,"d":"0.00"},{"v":0.101195483779844,"d":"0.10"},"down","yes"]
["MSTRG.5121","AQP9","ENST00000219919;ENST00000558772;ENST00000536493;ENST00000559443","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005215(transporter activity);GO:0055085(transmembrane transport);GO:0008152(metabolic process);GO:0005886(plasma membrane);GO:1905039(carboxylic acid transmembrane transport);GO:0043231(intracellular membrane-bounded organelle);GO:0005887(integral component of plasma membrane);GO:0006955(immune response);GO:0010033(response to organic substance);GO:0072531(pyrimidine-containing compound transmembrane transport);GO:1904823(purine nucleobase transmembrane transport);GO:0015250(water channel activity);GO:0015254(glycerol channel activity);GO:0006833(water transport);GO:0015793(glycerol transport);GO:0006970(response to osmotic stress);GO:0005275(amine transmembrane transporter activity);GO:0005345(purine nucleobase transmembrane transporter activity);GO:0005350(pyrimidine nucleobase transmembrane transporter activity);GO:0005372(water transmembrane transporter activity);GO:0015166(polyol transmembrane transporter activity);GO:0015265(urea channel activity);GO:0015288(porin activity);GO:0046943(carboxylic acid transmembrane transporter activity);GO:0006863(purine nucleobase transport);GO:0007588(excretion);GO:0015791(polyol transport);GO:0015837(amine transport);GO:0015855(pyrimidine nucleobase transport);GO:0030104(water homeostasis);GO:0046689(response to mercury ion);GO:0046942(carboxylic acid transport);GO:0071320(cellular response to cAMP);GO:0071918(urea transmembrane transport);GO:0015722(canalicular bile acid transport);GO:0016323(basolateral plasma membrane);GO:0016323(basolateral plasma membrane)","04976(Bile secretion);04976(Bile secretion)","K09877","NA","aquaporin 9 [Source:HGNC Symbol;Acc:HGNC:643]",{"v":33.5771783931994,"d":"33.58"},{"v":151.794756652241,"d":"151.79"},{"v":0.221201174096705,"d":"0.22"},{"v":-2.17656905172433,"d":"-2.18"},{"v":0.00159893018652383,"d":"0.00"},{"v":0.101338512137473,"d":"0.10"},"down","yes"]
["ENSG00000185909","KLHDC8B","ENST00000332780;ENST00000459846;ENST00000471811;ENST00000476495","GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0016567(protein ubiquitination);GO:0004842(ubiquitin-protein transferase activity);GO:0031463(Cul3-RING ubiquitin ligase complex);GO:0031463(Cul3-RING ubiquitin ligase complex)","NA","NA","NA","kelch domain containing 8B [Source:HGNC Symbol;Acc:HGNC:28557]",{"v":0.622252086190917,"d":"0.62"},{"v":2.97844501482854,"d":"2.98"},{"v":0.208918440022549,"d":"0.21"},{"v":-2.25898825851398,"d":"-2.26"},{"v":0.001617205320096,"d":"0.00"},{"v":0.101960138558095,"d":"0.10"},"down","yes"]
["MSTRG.10099","IL17RA","ENST00000612619;ENST00000319363;ENST00000459971;ENST00000477874","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0019221(cytokine-mediated signaling pathway);GO:0005887(integral component of plasma membrane);GO:0007166(cell surface receptor signaling pathway);GO:0032747(positive regulation of interleukin-23 production);GO:0072537(fibroblast activation);GO:0097398(cellular response to interleukin-17);GO:0030368(interleukin-17 receptor activity);GO:0005102(receptor binding);GO:0050729(positive regulation of inflammatory response);GO:0050832(defense response to fungus);GO:0071345(cellular response to cytokine stimulus);GO:0071621(granulocyte chemotaxis);GO:1900017(positive regulation of cytokine production involved in inflammatory response);GO:2000664(positive regulation of interleukin-5 secretion);GO:2000667(positive regulation of interleukin-13 secretion);GO:2000667(positive regulation of interleukin-13 secretion)","04060(Cytokine-cytokine receptor interaction);04657(IL-17 signaling pathway);04657(IL-17 signaling pathway)","K05164","NA","interleukin 17 receptor A [Source:HGNC Symbol;Acc:HGNC:5985]",{"v":8.62700442120407,"d":"8.63"},{"v":38.8755764146746,"d":"38.88"},{"v":0.221913222049296,"d":"0.22"},{"v":-2.17193246603354,"d":"-2.17"},{"v":1.63659322332586E-3,"d":"0.00"},{"v":0.102171201623385,"d":"0.10"},"down","yes"]
["MSTRG.1354","C4BPA","ENST00000367070;ENST00000424088;ENST00000421786","GO:0005615(extracellular space);GO:0003723(RNA binding);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0002376(immune system process);GO:0045087(innate immune response);GO:0030449(regulation of complement activation);GO:0005886(plasma membrane);GO:0072562(blood microparticle);GO:0006958(complement activation, classical pathway);GO:0045732(positive regulation of protein catabolic process);GO:0045959(negative regulation of complement activation, classical pathway);GO:1903027(regulation of opsonization);GO:0044216(other organism cell);GO:0044216(other organism cell)","04610(Complement and coagulation cascades);05133(Pertussis);05133(Pertussis)","K04002","NA","complement component 4 binding protein alpha [Source:HGNC Symbol;Acc:HGNC:1325]",{"v":1.14891227570668,"d":"1.15"},{"v":5.31165263129865,"d":"5.31"},{"v":0.216300341053323,"d":"0.22"},{"v":-2.20889215480453,"d":"-2.21"},{"v":1.63752216519792E-3,"d":"0.00"},{"v":0.102171201623385,"d":"0.10"},"down","yes"]
["ENSG00000151715","TMEM45B","ENST00000525709;ENST00000527754;ENST00000529381;ENST00000281441;ENST00000524567","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016021(integral component of membrane)","NA","NA","NA","transmembrane protein 45B [Source:HGNC Symbol;Acc:HGNC:25194]",{"v":0.204706010901883,"d":"0.20"},{"v":1.01873528080608,"d":"1.02"},{"v":0.200941318867359,"d":"0.20"},{"v":-2.31515384392785,"d":"-2.32"},{"v":1.66894825139757E-3,"d":"0.00"},{"v":0.102932443757108,"d":"0.10"},"down","yes"]
["MSTRG.3519","RASSF3","ENST00000542104;ENST00000637125;ENST00000283172","GO:0007165(signal transduction);GO:0042981(regulation of apoptotic process);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0005874(microtubule);GO:0042802(identical protein binding);GO:0042802(identical protein binding)","NA","NA","NA","Ras association domain family member 3 [Source:HGNC Symbol;Acc:HGNC:14271]",{"v":30.4586230560814,"d":"30.46"},{"v":7.02920397917653,"d":"7.03"},{"v":4.3331539597247,"d":"4.33"},{"v":2.11541749739568,"d":"2.12"},{"v":0.00167479873680535,"d":"0.00"},{"v":0.102932443757108,"d":"0.10"},"up","yes"]
["MSTRG.8615","YPEL5","ENST00000261353;ENST00000379519;ENST00000379520;ENST00000495673;ENST00000402003;ENST00000492439;ENST00000470120;ENST00000490211;ENST00000402708","GO:0046872(metal ion binding);GO:0005576(extracellular region);GO:0043312(neutrophil degranulation);GO:1904813(ficolin-1-rich granule lumen);GO:1904724(tertiary granule lumen);GO:1904724(tertiary granule lumen)","NA","NA","NA","yippee like 5 [Source:HGNC Symbol;Acc:HGNC:18329]",{"v":4.4899290935399,"d":"4.49"},{"v":20.2556740549547,"d":"20.26"},{"v":0.221662783541959,"d":"0.22"},{"v":-2.17356152813978,"d":"-2.17"},{"v":1.67536613323312E-3,"d":"0.00"},{"v":0.102932443757108,"d":"0.10"},"down","yes"]
["MSTRG.14033","CLEC5A","ENST00000546910;ENST00000551012;ENST00000438351;ENST00000481301","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0030246(carbohydrate binding);GO:0005886(plasma membrane);GO:0002376(immune system process);GO:0045087(innate immune response);GO:0046718(viral entry into host cell);GO:0001618(virus receptor activity);GO:0002076(osteoblast development);GO:0030099(myeloid cell differentiation);GO:0033033(negative regulation of myeloid cell apoptotic process);GO:0043066(negative regulation of apoptotic process);GO:0050715(positive regulation of cytokine secretion);GO:0009986(cell surface);GO:0016032(viral process);GO:0005887(integral component of plasma membrane);GO:0043312(neutrophil degranulation);GO:0035579(specific granule membrane);GO:0070821(tertiary granule membrane);GO:0007165(signal transduction);GO:0006968(cellular defense response);GO:0006968(cellular defense response)","NA","NA","NA","C-type lectin domain containing 5A [Source:HGNC Symbol;Acc:HGNC:2054]",{"v":0.34218211939937,"d":"0.34"},{"v":1.604220031969,"d":"1.60"},{"v":0.213301238346575,"d":"0.21"},{"v":-2.22903575344105,"d":"-2.23"},{"v":0.00169227951329277,"d":"0.00"},{"v":0.103443806594272,"d":"0.10"},"down","yes"]
["MSTRG.1884","CCNJ","ENST00000265992;ENST00000465148;ENST00000403870","GO:0005634(nucleus);GO:0005634(nucleus)","NA","NA","NA","cyclin J [Source:HGNC Symbol;Acc:HGNC:23434]",{"v":0.261313412487946,"d":"0.26"},{"v":1.23020940814851,"d":"1.23"},{"v":0.212413765296453,"d":"0.21"},{"v":-2.23505083306997,"d":"-2.24"},{"v":1.74041591320861E-3,"d":"0.00"},{"v":0.105848931448778,"d":"0.11"},"down","yes"]
["ENSG00000152683","SLC30A6","ENST00000282587;ENST00000454324;ENST00000357055;ENST00000457724;ENST00000449777;ENST00000379343;ENST00000435660","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0055085(transmembrane transport);GO:0098655(cation transmembrane transport);GO:0006812(cation transport);GO:0008324(cation transmembrane transporter activity);GO:0006810(transport);GO:0005794(Golgi apparatus);GO:0006811(ion transport);GO:0071577(zinc II ion transmembrane transport);GO:0005385(zinc ion transmembrane transporter activity);GO:0000139(Golgi membrane);GO:0006829(zinc II ion transport);GO:0010043(response to zinc ion);GO:0061088(regulation of sequestering of zinc ion);GO:0061088(regulation of sequestering of zinc ion)","NA","NA","NA","solute carrier family 30 member 6 [Source:HGNC Symbol;Acc:HGNC:19305]",{"v":1.95539931737523,"d":"1.96"},{"v":0.442790545656192,"d":"0.44"},{"v":4.41608190725353,"d":"4.42"},{"v":2.14276693074213,"d":"2.14"},{"v":0.00179130796830702,"d":"0.00"},{"v":0.108396635951523,"d":"0.11"},"up","yes"]
["MSTRG.1158","HSPA6;FCGR2A;FCGR2C;HSPA7;AL590385.2","ENST00000309758;MSTRG.1158.14;ENST00000466542;ENST00000611236;ENST00000471026;ENST00000486608;ENST00000483665;ENST00000367972;ENST00000497474;ENST00000461298;MSTRG.1158.3;ENST00000465075;ENST00000271450;ENST00000473530;MSTRG.1158.7;ENST00000473080;ENST00000467903;MSTRG.1158.11;MSTRG.1158.1;MSTRG.1158.10;ENST00000445535;MSTRG.1158.6;MSTRG.1158.2;ENST00000537821;ENST00000508651;ENST00000482233;MSTRG.1158.4;ENST00000543859;MSTRG.1158.37;MSTRG.1158.12;ENST00000536731;ENST00000496692;ENST00000507374;ENST00000467525;ENST00000473712;MSTRG.1158.5;ENST00000467654;ENST00000502411","GO:0005737(cytoplasm);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0005829(cytosol);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0070062(extracellular exosome);GO:0005814(centriole);GO:0008180(COP9 signalosome);GO:0072562(blood microparticle);GO:0043312(neutrophil degranulation);GO:0034774(secretory granule lumen);GO:1904813(ficolin-1-rich granule lumen);GO:0051082(unfolded protein binding);GO:0019899(enzyme binding);GO:0006986(response to unfolded protein);GO:0034605(cellular response to heat);GO:0042623(ATPase activity, coupled);GO:0042026(protein refolding);GO:0031072(heat shock protein binding);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005886(plasma membrane);GO:0002376(immune system process);GO:0038096(Fc-gamma receptor signaling pathway involved in phagocytosis);GO:0030667(secretory granule membrane);GO:0019864(IgG binding);GO:0016021(integral component of membrane)","03040(Spliceosome);04141(Protein processing in endoplasmic reticulum);04010(MAPK signaling pathway);04144(Endocytosis);04612(Antigen processing and presentation);04915(Estrogen signaling pathway);04213(Longevity regulating pathway - multiple species);05134(Legionellosis);05162(Measles);05164(Influenza A);05169(Epstein-Barr virus infection);05145(Toxoplasmosis);04145(Phagosome);04611(Platelet activation);04666(Fc gamma R-mediated phagocytosis);04380(Osteoclast differentiation);05322(Systemic lupus erythematosus);05150(Staphylococcus aureus infection);05152(Tuberculosis);05140(Leishmaniasis);05140(Leishmaniasis)","K03283;K06472","NA","heat shock protein family A (Hsp70) member 6 [Source:HGNC Symbol;Acc:HGNC:5239];Fc fragment of IgG receptor IIc (gene/pseudogene) [Source:HGNC Symbol;Acc:HGNC:15626];Fc fragment of IgG receptor IIa [Source:HGNC Symbol;Acc:HGNC:3616];heat shock protein family A (Hsp70) member 7 [Source:HGNC Symbol;Acc:HGNC:5240]",{"v":4.31944401202985,"d":"4.32"},{"v":19.1624630697934,"d":"19.16"},{"v":0.225411733152341,"d":"0.23"},{"v":-2.14936548212729,"d":"-2.15"},{"v":1.83475756770347E-3,"d":"0.00"},{"v":0.110093632429596,"d":"0.11"},"down","yes"]
["ENSG00000146122","DAAM2","ENST00000274867;ENST00000491083;ENST00000538976;ENST00000398904;ENST00000632657;ENST00000405961;ENST00000475489","GO:0003779(actin binding);GO:0030036(actin cytoskeleton organization);GO:0016043(cellular component organization);GO:0017048(Rho GTPase binding);GO:0070062(extracellular exosome);GO:0007368(determination of left/right symmetry);GO:0007368(determination of left/right symmetry)","04310(Wnt signaling pathway);04310(Wnt signaling pathway)","K04512","NA","dishevelled associated activator of morphogenesis 2 [Source:HGNC Symbol;Acc:HGNC:18143]",{"v":0.0897716322655346,"d":"0.09"},{"v":0.416359766885372,"d":"0.42"},{"v":0.215610727561603,"d":"0.22"},{"v":-2.2134991347241,"d":"-2.21"},{"v":1.83763661504308E-3,"d":"0.00"},{"v":0.110093632429596,"d":"0.11"},"down","yes"]
["ENSG00000178761","FAM219B","ENST00000357635;ENST00000563413;ENST00000563671;ENST00000565772;ENST00000570143;ENST00000563069;ENST00000569524;ENST00000562698;ENST00000563119;ENST00000563706;ENST00000564857;ENST00000566132;ENST00000563877;ENST00000566894;ENST00000564019;ENST00000566194","NA","NA","NA","NA","family with sequence similarity 219 member B [Source:HGNC Symbol;Acc:HGNC:24695]",{"v":0.373889307341194,"d":"0.37"},{"v":1.724172,"d":"1.72"},{"v":0.21685151327199,"d":"0.22"},{"v":-2.20522058397881,"d":"-2.21"},{"v":0.00189098116707669,"d":"0.00"},{"v":0.112728689177909,"d":"0.11"},"down","yes"]
["MSTRG.7582","R3HDM4","ENST00000587975;ENST00000361574;MSTRG.7582.2;ENST00000589428;ENST00000589445;MSTRG.7582.1;ENST00000590454;ENST00000586080;ENST00000591829","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0005634(nucleus)","NA","NA","NA","R3H domain containing 4 [Source:HGNC Symbol;Acc:HGNC:28270]",{"v":33.2053283675431,"d":"33.21"},{"v":146.084655926491,"d":"146.08"},{"v":0.227301958285419,"d":"0.23"},{"v":-2.13731798135856,"d":"-2.14"},{"v":0.00192038349207614,"d":"0.00"},{"v":0.113917527150645,"d":"0.11"},"down","yes"]
["MSTRG.8222","ZNF296;AC011489.1","ENST00000303809;ENST00000586744;ENST00000586556","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0007283(spermatogenesis);GO:0003674(molecular_function);GO:0005575(cellular_component);GO:0001076(transcription factor activity, RNA polymerase II transcription factor binding);GO:0000122(negative regulation of transcription from RNA polymerase II promoter)","NA","NA","NA","zinc finger protein 296 [Source:HGNC Symbol;Acc:HGNC:15981]",{"v":0.253788958380202,"d":"0.25"},{"v":1.22402613573303,"d":"1.22"},{"v":0.207339492982489,"d":"0.21"},{"v":-2.26993315497954,"d":"-2.27"},{"v":0.0019794459813888,"d":"0.00"},{"v":0.116845531901392,"d":"0.12"},"down","yes"]
["MSTRG.3581","AC024909.3","ENST00000611513","NA","NA","NA","NA",null,{"v":0.529752,"d":"0.53"},{"v":2.443112,"d":"2.44"},{"v":0.216834922017492,"d":"0.22"},{"v":-2.20533096843473,"d":"-2.21"},{"v":0.00200523983931209,"d":"0.00"},{"v":0.117254958925203,"d":"0.12"},"down","yes"]
["MSTRG.6792","MIEN1","ENST00000394231;ENST00000582963;ENST00000498164;ENST00000577810;ENST00000474210;ENST00000469568","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0006915(apoptotic process);GO:0070062(extracellular exosome);GO:0030335(positive regulation of cell migration);GO:0043066(negative regulation of apoptotic process);GO:0051491(positive regulation of filopodium assembly);GO:0031235(intrinsic component of the cytoplasmic side of the plasma membrane);GO:0031235(intrinsic component of the cytoplasmic side of the plasma membrane)","NA","NA","NA","migration and invasion enhancer 1 [Source:HGNC Symbol;Acc:HGNC:28230]",{"v":1.25785090488656,"d":"1.26"},{"v":5.64796222251309,"d":"5.65"},{"v":0.222708802809037,"d":"0.22"},{"v":-2.1667695115351,"d":"-2.17"},{"v":0.00200585629784021,"d":"0.00"},{"v":0.117254958925203,"d":"0.12"},"down","yes"]
["ENSG00000213096","ZNF254","ENST00000357002;ENST00000595187;ENST00000611359;ENST00000339642;ENST00000616028;ENST00000593783;ENST00000594886","GO:0003676(nucleic acid binding);GO:0006355(regulation of transcription, DNA-templated);GO:0005622(intracellular);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0000122(negative regulation of transcription from RNA polymerase II promoter)","NA","NA","NA","zinc finger protein 254 [Source:HGNC Symbol;Acc:HGNC:13047]",{"v":0.188447561694291,"d":"0.19"},{"v":0.858524817284925,"d":"0.86"},{"v":0.219501589121505,"d":"0.22"},{"v":-2.18769671043691,"d":"-2.19"},{"v":2.04977654211456E-3,"d":"0.00"},{"v":0.119084764844145,"d":"0.12"},"down","yes"]
["MSTRG.11653","JCHAIN","ENST00000543780;ENST00000254801;ENST00000470866;ENST00000510437;ENST00000510614;ENST00000391614","GO:0042803(protein homodimerization activity);GO:0005576(extracellular region);GO:0006955(immune response);GO:0005615(extracellular space);GO:0045087(innate immune response);GO:0003823(antigen binding);GO:0002250(adaptive immune response);GO:0006898(receptor-mediated endocytosis);GO:0050900(leukocyte migration);GO:0031210(phosphatidylcholine binding);GO:0070062(extracellular exosome);GO:0001895(retina homeostasis);GO:0072562(blood microparticle);GO:0019731(antibacterial humoral response);GO:0032461(positive regulation of protein oligomerization);GO:0003697(single-stranded DNA binding);GO:0042834(peptidoglycan binding);GO:0034987(immunoglobulin receptor binding);GO:0019862(IgA binding);GO:0030674(protein binding, bridging);GO:0003094(glomerular filtration);GO:0060267(positive regulation of respiratory burst);GO:0071748(monomeric IgA immunoglobulin complex);GO:0071750(dimeric IgA immunoglobulin complex);GO:0071751(secretory IgA immunoglobulin complex);GO:0071752(secretory dimeric IgA immunoglobulin complex);GO:0071756(pentameric IgM immunoglobulin complex);GO:0071756(pentameric IgM immunoglobulin complex)","NA","NA","NA","joining chain of multimeric IgA and IgM [Source:HGNC Symbol;Acc:HGNC:5713]",{"v":75.1253624333333,"d":"75.13"},{"v":17.869626627381,"d":"17.87"},{"v":4.20408126033374,"d":"4.20"},{"v":2.07179055530092,"d":"2.07"},{"v":0.00205693664570521,"d":"0.00"},{"v":0.119084764844145,"d":"0.12"},"up","yes"]
["MSTRG.11896","FTH1P21","MSTRG.11896.1","NA","NA","NA","NA",null,{"v":1.653372,"d":"1.65"},{"v":7.542551,"d":"7.54"},{"v":0.2192059423927,"d":"0.22"},{"v":-2.18964118644168,"d":"-2.19"},{"v":2.12366084600547E-3,"d":"0.00"},{"v":0.122177203800765,"d":"0.12"},"down","yes"]
["ENSG00000182749","PAQR7","ENST00000374296","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005886(plasma membrane);GO:0007275(multicellular organism development);GO:0030154(cell differentiation);GO:0043401(steroid hormone mediated signaling pathway);GO:0008289(lipid binding);GO:0048477(oogenesis);GO:0005496(steroid binding);GO:0003707(steroid hormone receptor activity);GO:0048545(response to steroid hormone)","NA","NA","NA","progestin and adipoQ receptor family member 7 [Source:HGNC Symbol;Acc:HGNC:23146]",{"v":2.510026,"d":"2.51"},{"v":0.582825,"d":"0.58"},{"v":4.3066546562004,"d":"4.31"},{"v":2.10656764079303,"d":"2.11"},{"v":0.00213261633586638,"d":"0.00"},{"v":0.122177203800765,"d":"0.12"},"up","yes"]
["MSTRG.9104","CCDC115","ENST00000259229;ENST00000465315;ENST00000409127;ENST00000442217","GO:0016020(membrane);GO:0005783(endoplasmic reticulum);GO:0005764(lysosome);GO:0031410(cytoplasmic vesicle);GO:0006879(cellular iron ion homeostasis);GO:0005768(endosome);GO:0005793(endoplasmic reticulum-Golgi intermediate compartment);GO:0036295(cellular response to increased oxygen levels);GO:0007042(lysosomal lumen acidification);GO:0051082(unfolded protein binding);GO:1905146(lysosomal protein catabolic process);GO:0030137(COPI-coated vesicle);GO:0016471(vacuolar proton-transporting V-type ATPase complex);GO:0042406(extrinsic component of endoplasmic reticulum membrane);GO:0042406(extrinsic component of endoplasmic reticulum membrane)","NA","NA","NA","coiled-coil domain containing 115 [Source:HGNC Symbol;Acc:HGNC:28178]",{"v":1.23638690904283,"d":"1.24"},{"v":5.41519767186674,"d":"5.42"},{"v":0.228317964359114,"d":"0.23"},{"v":-2.13088371770677,"d":"-2.13"},{"v":0.00214078973608715,"d":"0.00"},{"v":0.122177203800765,"d":"0.12"},"down","yes"]
["MSTRG.11680","ANXA3","ENST00000264908;MSTRG.11680.10;ENST00000503776;ENST00000510502;ENST00000512542;ENST00000505805;ENST00000503570;ENST00000512884;ENST00000508214","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005829(cytosol);GO:0005509(calcium ion binding);GO:0005886(plasma membrane);GO:0043086(negative regulation of catalytic activity);GO:0004859(phospholipase inhibitor activity);GO:0005544(calcium-dependent phospholipid binding);GO:0042742(defense response to bacterium);GO:0070062(extracellular exosome);GO:0030670(phagocytic vesicle membrane);GO:0042581(specific granule);GO:0043312(neutrophil degranulation);GO:0006909(phagocytosis);GO:0051091(positive regulation of sequence-specific DNA binding transcription factor activity);GO:0045766(positive regulation of angiogenesis);GO:0010595(positive regulation of endothelial cell migration);GO:0048306(calcium-dependent protein binding);GO:0019834(phospholipase A2 inhibitor activity);GO:0021766(hippocampus development);GO:0031100(animal organ regeneration);GO:0051054(positive regulation of DNA metabolic process);GO:0051384(response to glucocorticoid);GO:0070848(response to growth factor);GO:0030424(axon);GO:0030425(dendrite);GO:0043025(neuronal cell body);GO:0043025(neuronal cell body)","NA","NA","NA","annexin A3 [Source:HGNC Symbol;Acc:HGNC:541]",{"v":1.99362490182607,"d":"1.99"},{"v":8.67392388465015,"d":"8.67"},{"v":0.229841180109281,"d":"0.23"},{"v":-2.12129078943197,"d":"-2.12"},{"v":0.0021709889584401,"d":"0.00"},{"v":0.123108343897157,"d":"0.12"},"down","yes"]
["ENSG00000196428","TSC22D2","ENST00000361875;ENST00000460316;ENST00000492828;ENST00000485421;ENST00000466814","GO:0006355(regulation of transcription, DNA-templated);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0006970(response to osmotic stress);GO:0006970(response to osmotic stress)","NA","NA","NA","TSC22 domain family member 2 [Source:HGNC Symbol;Acc:HGNC:29095]",{"v":0.20040149272011,"d":"0.20"},{"v":0.890825256937307,"d":"0.89"},{"v":0.224961619755931,"d":"0.22"},{"v":-2.15224920771564,"d":"-2.15"},{"v":0.00217755167331792,"d":"0.00"},{"v":0.123108343897157,"d":"0.12"},"down","yes"]
["ENSG00000197312","DDI2","ENST00000480945;ENST00000548451;ENST00000483899;ENST00000486680;ENST00000546927","GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0006508(proteolysis);GO:0042802(identical protein binding);GO:0043130(ubiquitin binding);GO:0043130(ubiquitin binding)","NA","NA","NA","DNA damage inducible 1 homolog 2 [Source:HGNC Symbol;Acc:HGNC:24578]",{"v":2.11151569602835,"d":"2.11"},{"v":0.503878138843111,"d":"0.50"},{"v":4.19052848944057,"d":"4.19"},{"v":2.0671322012074,"d":"2.07"},{"v":0.00219453104575799,"d":"0.00"},{"v":0.123488518004756,"d":"0.12"},"up","yes"]
["MSTRG.209","MRTO4","ENST00000330263;ENST00000479559;ENST00000493700","GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005622(intracellular);GO:0005515(protein binding);GO:0000027(ribosomal large subunit assembly);GO:0042254(ribosome biogenesis);GO:0005730(nucleolus);GO:0006364(rRNA processing);GO:0000956(nuclear-transcribed mRNA catabolic process);GO:0000956(nuclear-transcribed mRNA catabolic process)","NA","NA","NA","MRT4 homolog, ribosome maturation factor [Source:HGNC Symbol;Acc:HGNC:18477]",{"v":3.1627654528703,"d":"3.16"},{"v":0.736954625797307,"d":"0.74"},{"v":4.29166917766277,"d":"4.29"},{"v":2.10153887056316,"d":"2.10"},{"v":0.00221820078072025,"d":"0.00"},{"v":0.123767785365213,"d":"0.12"},"up","yes"]
["MSTRG.7397","AP005202.1","ENST00000489915","NA","NA","NA","NA",null,{"v":9.39108946788991,"d":"9.39"},{"v":40.7261229323395,"d":"40.73"},{"v":0.23059129599672,"d":"0.23"},{"v":-2.116590037489,"d":"-2.12"},{"v":2.22004996170786E-3,"d":"0.00"},{"v":0.123767785365213,"d":"0.12"},"down","yes"]
["ENSG00000146021","KLHL3","ENST00000509694;ENST00000512977;ENST00000504496;ENST00000510529;ENST00000504208;ENST00000506873;ENST00000309755;ENST00000506491;ENST00000447439;ENST00000508657","GO:0005737(cytoplasm);GO:0016567(protein ubiquitination);GO:0003779(actin binding);GO:0005829(cytosol);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0004842(ubiquitin-protein transferase activity);GO:0043687(post-translational protein modification);GO:0042787(protein ubiquitination involved in ubiquitin-dependent protein catabolic process);GO:0070294(renal sodium ion absorption);GO:0005198(structural molecule activity);GO:0070936(protein K48-linked ubiquitination);GO:0031463(Cul3-RING ubiquitin ligase complex);GO:0050801(ion homeostasis);GO:0072156(distal tubule morphogenesis);GO:0072156(distal tubule morphogenesis)","NA","NA","NA","kelch like family member 3 [Source:HGNC Symbol;Acc:HGNC:6354]",{"v":0.456175407204319,"d":"0.46"},{"v":0.105283344018897,"d":"0.11"},{"v":4.33283546847108,"d":"4.33"},{"v":2.11531145393551,"d":"2.12"},{"v":0.00223494862025077,"d":"0.00"},{"v":0.12398111727138,"d":"0.12"},"up","yes"]
["MSTRG.3433","GDF11","ENST00000257868","GO:0043231(intracellular membrane-bounded organelle);GO:0005654(nucleoplasm);GO:0008083(growth factor activity);GO:0005576(extracellular region);GO:0005125(cytokine activity);GO:0005615(extracellular space);GO:0007399(nervous system development);GO:0001501(skeletal system development);GO:0001656(metanephros development);GO:0001657(ureteric bud development);GO:0008285(negative regulation of cell proliferation);GO:0009887(animal organ morphogenesis);GO:0009952(anterior/posterior pattern specification);GO:0021512(spinal cord anterior/posterior patterning);GO:0031016(pancreas development);GO:0045596(negative regulation of cell differentiation);GO:0048469(cell maturation);GO:0048593(camera-type eye morphogenesis);GO:0060021(palate development);GO:0060395(SMAD protein signal transduction);GO:0005515(protein binding);GO:0005575(cellular_component);GO:0043234(protein complex);GO:0005160(transforming growth factor beta receptor binding);GO:0010862(positive regulation of pathway-restricted SMAD protein phosphorylation);GO:0042981(regulation of apoptotic process);GO:0043408(regulation of MAPK cascade);GO:0048468(cell development);GO:0007498(mesoderm development)","NA","NA","NA","growth differentiation factor 11 [Source:HGNC Symbol;Acc:HGNC:4216]",{"v":1.537424,"d":"1.54"},{"v":0.366031,"d":"0.37"},{"v":4.20025626244772,"d":"4.20"},{"v":2.07047735105428,"d":"2.07"},{"v":2.25057693123686E-3,"d":"0.00"},{"v":0.12398111727138,"d":"0.12"},"up","yes"]
["ENSG00000157823","AP3S2","ENST00000558806;ENST00000560771;ENST00000617003;ENST00000558926;ENST00000336418;ENST00000559162;ENST00000560940;ENST00000558999;ENST00000558186;ENST00000559601;ENST00000558011;ENST00000423566;ENST00000560184","GO:0006810(transport);GO:0016020(membrane);GO:0008565(protein transporter activity);GO:0006886(intracellular protein transport);GO:0015031(protein transport);GO:0016192(vesicle-mediated transport);GO:0030117(membrane coat);GO:0043231(intracellular membrane-bounded organelle);GO:0005794(Golgi apparatus);GO:1904115(axon cytoplasm);GO:0030659(cytoplasmic vesicle membrane);GO:0031410(cytoplasmic vesicle);GO:0008089(anterograde axonal transport);GO:0048490(anterograde synaptic vesicle transport);GO:0030123(AP-3 adaptor complex);GO:0030123(AP-3 adaptor complex)","04142(Lysosome);04142(Lysosome)","K12399","NA","adaptor related protein complex 3 sigma 2 subunit [Source:HGNC Symbol;Acc:HGNC:571]",{"v":0.378000658222367,"d":"0.38"},{"v":1.67418845534264,"d":"1.67"},{"v":0.225781426825695,"d":"0.23"},{"v":-2.14700128250786,"d":"-2.15"},{"v":0.00226383739853217,"d":"0.00"},{"v":0.12398111727138,"d":"0.12"},"down","yes"]
["MSTRG.5923","AC007342.3","ENST00000565421;MSTRG.5923.2;ENST00000565598;MSTRG.5923.3","NA","NA","NA","NA",null,{"v":1.94606602974969,"d":"1.95"},{"v":8.41130510443168,"d":"8.41"},{"v":0.231363148237764,"d":"0.23"},{"v":-2.11176900610556,"d":"-2.11"},{"v":2.26505944192855E-3,"d":"0.00"},{"v":0.12398111727138,"d":"0.12"},"down","yes"]
["MSTRG.11073","GPR27","ENST00000304411","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0004930(G-protein coupled receptor activity);GO:0007186(G-protein coupled receptor signaling pathway);GO:0005886(plasma membrane);GO:0004871(signal transducer activity);GO:0007165(signal transduction);GO:0035774(positive regulation of insulin secretion involved in cellular response to glucose stimulus);GO:1900738(positive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway)","NA","NA","NA","G protein-coupled receptor 27 [Source:HGNC Symbol;Acc:HGNC:4482]",{"v":1.944609,"d":"1.94"},{"v":8.44001,"d":"8.44"},{"v":0.230403636962515,"d":"0.23"},{"v":-2.11776460472879,"d":"-2.12"},{"v":0.00229243041361149,"d":"0.00"},{"v":0.124166323804829,"d":"0.12"},"down","yes"]
["ENSG00000185052","SLC24A3","ENST00000328041;ENST00000613834","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0055085(transmembrane transport);GO:0006811(ion transport);GO:0005886(plasma membrane);GO:0015293(symporter activity);GO:0006813(potassium ion transport);GO:0015297(antiporter activity);GO:0006814(sodium ion transport);GO:0035725(sodium ion transmembrane transport);GO:0006816(calcium ion transport);GO:0070588(calcium ion transmembrane transport);GO:0005887(integral component of plasma membrane);GO:0005509(calcium ion binding);GO:0008273(calcium, potassium:sodium antiporter activity);GO:0005262(calcium channel activity);GO:0030955(potassium ion binding);GO:0031402(sodium ion binding);GO:0006874(cellular calcium ion homeostasis);GO:0006874(cellular calcium ion homeostasis)","NA","NA","NA","solute carrier family 24 member 3 [Source:HGNC Symbol;Acc:HGNC:10977]",{"v":0.41809007424358,"d":"0.42"},{"v":1.84109776709891,"d":"1.84"},{"v":0.22708738325308,"d":"0.23"},{"v":-2.13868054130337,"d":"-2.14"},{"v":0.0022962990457573,"d":"0.00"},{"v":0.124166323804829,"d":"0.12"},"down","yes"]
["MSTRG.1767","VSIR","ENST00000394957;ENST00000481568;ENST00000470317","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005886(plasma membrane);GO:0005886(plasma membrane)","NA","NA","NA","V-set immunoregulatory receptor [Source:HGNC Symbol;Acc:HGNC:30085]",{"v":30.3602526731669,"d":"30.36"},{"v":129.924063050702,"d":"129.92"},{"v":0.233676902956145,"d":"0.23"},{"v":-2.097412952283,"d":"-2.10"},{"v":2.29937636675609E-3,"d":"0.00"},{"v":0.124166323804829,"d":"0.12"},"down","yes"]
["MSTRG.4745","IGHV3-21","ENST00000390607","GO:0016020(membrane);GO:0005886(plasma membrane);GO:0005576(extracellular region);GO:0002376(immune system process);GO:0003823(antigen binding);GO:0002250(adaptive immune response);GO:0034987(immunoglobulin receptor binding);GO:0006910(phagocytosis, recognition);GO:0006911(phagocytosis, engulfment);GO:0006958(complement activation, classical pathway);GO:0042742(defense response to bacterium);GO:0045087(innate immune response);GO:0050853(B cell receptor signaling pathway);GO:0050871(positive regulation of B cell activation);GO:0009897(external side of plasma membrane);GO:0042571(immunoglobulin complex, circulating);GO:0072562(blood microparticle)","NA","NA","NA","immunoglobulin heavy variable 3-21 [Source:HGNC Symbol;Acc:HGNC:5586]",{"v":9.976377,"d":"9.98"},{"v":2.302767,"d":"2.30"},{"v":4.33234322013473,"d":"4.33"},{"v":2.11514754173935,"d":"2.12"},{"v":0.002323327323731,"d":"0.00"},{"v":0.124899587644503,"d":"0.12"},"up","yes"]
["ENSG00000160179","ABCG1","ENST00000361802;ENST00000398449;ENST00000450121;ENST00000472587;ENST00000496783;ENST00000398457;ENST00000462050;ENST00000467818","GO:0042632(cholesterol homeostasis);GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0005794(Golgi apparatus);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005739(mitochondrion);GO:0005886(plasma membrane);GO:0000139(Golgi membrane);GO:0006869(lipid transport);GO:0016887(ATPase activity);GO:0005887(integral component of plasma membrane);GO:0055085(transmembrane transport);GO:0042803(protein homodimerization activity);GO:0046982(protein heterodimerization activity);GO:0009897(external side of plasma membrane);GO:0010033(response to organic substance);GO:1901998(toxin transport);GO:0033344(cholesterol efflux);GO:0046983(protein dimerization activity);GO:0006355(regulation of transcription, DNA-templated);GO:0019534(toxin transporter activity);GO:0015485(cholesterol binding);GO:0008203(cholesterol metabolic process);GO:0005543(phospholipid binding);GO:0034375(high-density lipoprotein particle remodeling);GO:0043691(reverse cholesterol transport);GO:0005548(phospholipid transporter activity);GO:0017127(cholesterol transporter activity);GO:0010745(negative regulation of macrophage derived foam cell differentiation);GO:0010887(negative regulation of cholesterol storage);GO:0032367(intracellular cholesterol transport);GO:0033700(phospholipid efflux);GO:0055091(phospholipid homeostasis);GO:0043531(ADP binding);GO:0034374(low-density lipoprotein particle remodeling);GO:0055037(recycling endosome);GO:0045542(positive regulation of cholesterol biosynthetic process);GO:0005768(endosome);GO:0033993(response to lipid);GO:0034041(sterol-transporting ATPase activity);GO:0034437(glycoprotein transporter activity);GO:0009720(detection of hormone stimulus);GO:0010872(regulation of cholesterol esterification);GO:0034436(glycoprotein transport);GO:0042987(amyloid precursor protein catabolic process);GO:0010875(positive regulation of cholesterol efflux);GO:0010888(negative regulation of lipid storage);GO:0030301(cholesterol transport);GO:0055099(response to high density lipoprotein particle);GO:0055099(response to high density lipoprotein particle)","02010(ABC transporters);02010(ABC transporters)","K05679","NA","ATP binding cassette subfamily G member 1 [Source:HGNC Symbol;Acc:HGNC:73]",{"v":1.09978131808528,"d":"1.10"},{"v":4.75759360480314,"d":"4.76"},{"v":0.231163358924766,"d":"0.23"},{"v":-2.11301535659379,"d":"-2.11"},{"v":0.00233536525694402,"d":"0.00"},{"v":0.124988748551644,"d":"0.12"},"down","yes"]
["MSTRG.5953","PLLP","ENST00000613167;ENST00000219207;ENST00000564376","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0006810(transport);GO:0006811(ion transport);GO:0005515(protein binding);GO:0009611(response to wounding);GO:0042552(myelination);GO:0043218(compact myelin);GO:0045121(membrane raft);GO:0070062(extracellular exosome);GO:0008104(protein localization);GO:0019911(structural constituent of myelin sheath);GO:0001766(membrane raft polarization);GO:0001766(membrane raft polarization)","NA","NA","NA","plasmolipin [Source:HGNC Symbol;Acc:HGNC:18553]",{"v":2.02625876146789,"d":"2.03"},{"v":0.486296521330275,"d":"0.49"},{"v":4.16671448918658,"d":"4.17"},{"v":2.0589102473535,"d":"2.06"},{"v":0.00236340561391934,"d":"0.00"},{"v":0.125929780543437,"d":"0.13"},"up","yes"]
["MSTRG.4085","GGACT;AL356966.1","ENST00000471912;ENST00000492399;ENST00000376250;ENST00000608779;ENST00000455100;ENST00000454752","GO:0016740(transferase activity);GO:0016746(transferase activity, transferring acyl groups);GO:0005515(protein binding);GO:0070062(extracellular exosome);GO:0003839(gamma-glutamylcyclotransferase activity);GO:0042219(cellular modified amino acid catabolic process);GO:0042219(cellular modified amino acid catabolic process)","NA","NA","NA","gamma-glutamylamine cyclotransferase [Source:HGNC Symbol;Acc:HGNC:25100]",{"v":0.0926147470817121,"d":"0.09"},{"v":0.442248885862516,"d":"0.44"},{"v":0.209417705826632,"d":"0.21"},{"v":-2.25554467063012,"d":"-2.26"},{"v":0.00238715755919,"d":"0.00"},{"v":0.126301846242994,"d":"0.13"},"down","yes"]
["MSTRG.15164","WWC3","ENST00000380861;ENST00000466248","GO:0032947(protein complex scaffold);GO:0005829(cytosol);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0019900(kinase binding);GO:0046621(negative regulation of organ growth);GO:0035331(negative regulation of hippo signaling);GO:0035331(negative regulation of hippo signaling)","NA","NA","NA","WWC family member 3 [Source:HGNC Symbol;Acc:HGNC:29237]",{"v":2.08750717064942,"d":"2.09"},{"v":8.90583889302783,"d":"8.91"},{"v":0.234397589685086,"d":"0.23"},{"v":-2.09297036031172,"d":"-2.09"},{"v":0.00239136530006666,"d":"0.00"},{"v":0.126301846242994,"d":"0.13"},"down","yes"]
["ENSG00000165714","BORCS5","ENST00000542728;ENST00000298571;ENST00000314565","GO:0016020(membrane);GO:0005765(lysosomal membrane);GO:0005515(protein binding);GO:0005764(lysosome);GO:0031224(intrinsic component of membrane);GO:0032418(lysosome localization);GO:0099078(BORC complex);GO:0005873(plus-end kinesin complex);GO:0072384(organelle transport along microtubule);GO:0098574(cytoplasmic side of lysosomal membrane);GO:0098574(cytoplasmic side of lysosomal membrane)","NA","NA","NA","BLOC-1 related complex subunit 5 [Source:HGNC Symbol;Acc:HGNC:17950]",{"v":0.80629637751004,"d":"0.81"},{"v":0.18364538313253,"d":"0.18"},{"v":4.39050720337557,"d":"4.39"},{"v":2.13438761345693,"d":"2.13"},{"v":0.00241531113303838,"d":"0.00"},{"v":0.12700950508318,"d":"0.13"},"up","yes"]
["MSTRG.8133","MED29","ENST00000315588;ENST00000615911;ENST00000594368;ENST00000596297;ENST00000599213;ENST00000600973","GO:0005654(nucleoplasm);GO:0016592(mediator complex);GO:0005634(nucleus);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0005515(protein binding);GO:0005515(protein binding)","NA","NA","NA","mediator complex subunit 29 [Source:HGNC Symbol;Acc:HGNC:23074]",{"v":5.65878043102999,"d":"5.66"},{"v":1.36430865632334,"d":"1.36"},{"v":4.14772742575699,"d":"4.15"},{"v":2.05232108835808,"d":"2.05"},{"v":0.00243240572723442,"d":"0.00"},{"v":0.127053920490534,"d":"0.13"},"up","yes"]
["ENSG00000073150","PANX2","ENST00000395842;ENST00000402472;ENST00000159647","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0006811(ion transport);GO:0005886(plasma membrane);GO:0005921(gap junction);GO:0030054(cell junction);GO:0012505(endomembrane system);GO:0007267(cell-cell signaling);GO:0034214(protein hexamerization);GO:0022829(wide pore channel activity);GO:0055077(gap junction hemi-channel activity);GO:0006812(cation transport);GO:0015267(channel activity);GO:0002931(response to ischemia);GO:0055085(transmembrane transport);GO:0005737(cytoplasm);GO:0005737(cytoplasm)","NA","NA","NA","pannexin 2 [Source:HGNC Symbol;Acc:HGNC:8600]",{"v":1.27634431785945,"d":"1.28"},{"v":5.49009632172792,"d":"5.49"},{"v":0.232481224930083,"d":"0.23"},{"v":-2.1048138853075,"d":"-2.10"},{"v":0.00244061396680101,"d":"0.00"},{"v":0.127053920490534,"d":"0.13"},"down","yes"]
["MSTRG.9213","GCA","MSTRG.9213.5;ENST00000487445;ENST00000437150;ENST00000414723;ENST00000446271;ENST00000481161;ENST00000233612;ENST00000429691;ENST00000453113;ENST00000479199;ENST00000473240","GO:0005829(cytosol);GO:0005509(calcium ion binding);GO:0005886(plasma membrane);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0046872(metal ion binding);GO:0042803(protein homodimerization activity);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0070062(extracellular exosome);GO:0006508(proteolysis);GO:0004198(calcium-dependent cysteine-type endopeptidase activity);GO:0043312(neutrophil degranulation);GO:0046982(protein heterodimerization activity);GO:0061025(membrane fusion);GO:0035578(azurophil granule lumen);GO:0035578(azurophil granule lumen)","NA","NA","NA","grancalcin [Source:HGNC Symbol;Acc:HGNC:15990]",{"v":12.0468111514738,"d":"12.05"},{"v":51.169443297762,"d":"51.17"},{"v":0.235429787292618,"d":"0.24"},{"v":-2.08663122879891,"d":"-2.09"},{"v":2.44780846651752E-3,"d":"0.00"},{"v":0.127053920490534,"d":"0.13"},"down","yes"]
["ENSG00000183762","KREMEN1","ENST00000400335;ENST00000327813;ENST00000474001;ENST00000407188;ENST00000453585","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005886(plasma membrane);GO:0006915(apoptotic process);GO:0016055(Wnt signaling pathway);GO:0090090(negative regulation of canonical Wnt signaling pathway);GO:0005515(protein binding);GO:0007154(cell communication);GO:0060173(limb development);GO:0060828(regulation of canonical Wnt signaling pathway);GO:0030279(negative regulation of ossification);GO:0030279(negative regulation of ossification)","NA","NA","NA","kringle containing transmembrane protein 1 [Source:HGNC Symbol;Acc:HGNC:17550]",{"v":0.889176421587063,"d":"0.89"},{"v":3.78161124182023,"d":"3.78"},{"v":0.235131631658433,"d":"0.24"},{"v":-2.08845946075798,"d":"-2.09"},{"v":0.00254225166244886,"d":"0.00"},{"v":0.131234100827018,"d":"0.13"},"down","yes"]
["MSTRG.9891","AL118506.1","MSTRG.9891.1;ENST00000601296","NA","NA","NA","NA",null,{"v":2.53599744667274,"d":"2.54"},{"v":0.607985804010939,"d":"0.61"},{"v":4.1711458227191,"d":"4.17"},{"v":2.06044374954103,"d":"2.06"},{"v":2.55338527915992E-3,"d":"0.00"},{"v":0.131234100827018,"d":"0.13"},"up","yes"]
["MSTRG.1305","PPP1R12B","ENST00000391959;ENST00000465284;ENST00000480184;ENST00000466273;ENST00000608999;ENST00000634903;ENST00000498070;ENST00000434615;ENST00000618451","GO:0019901(protein kinase binding);GO:0005737(cytoplasm);GO:0043085(positive regulation of catalytic activity);GO:0005515(protein binding);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0000086(G2/M transition of mitotic cell cycle);GO:0007165(signal transduction);GO:0030018(Z disc);GO:0031672(A band);GO:0008047(enzyme activator activity);GO:0006937(regulation of muscle contraction);GO:0006937(regulation of muscle contraction)","04510(Focal adhesion);04810(Regulation of actin cytoskeleton);04921(Oxytocin signaling pathway);04270(Vascular smooth muscle contraction);05205(Proteoglycans in cancer);05205(Proteoglycans in cancer)","K12329","NA","protein phosphatase 1 regulatory subunit 12B [Source:HGNC Symbol;Acc:HGNC:7619]",{"v":0.358653333170037,"d":"0.36"},{"v":1.52683757593302,"d":"1.53"},{"v":0.234899467253988,"d":"0.23"},{"v":-2.08988465352917,"d":"-2.09"},{"v":0.00256103750991108,"d":"0.00"},{"v":0.131234100827018,"d":"0.13"},"down","yes"]
["ENSG00000127418","FGFRL1","ENST00000398484;ENST00000512562;ENST00000264748","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005794(Golgi apparatus);GO:0005886(plasma membrane);GO:0008201(heparin binding);GO:0030133(transport vesicle);GO:0008543(fibroblast growth factor receptor signaling pathway);GO:0051260(protein homooligomerization);GO:0044291(cell-cell contact zone);GO:0005007(fibroblast growth factor-activated receptor activity);GO:0098742(cell-cell adhesion via plasma-membrane adhesion molecules);GO:0017134(fibroblast growth factor binding);GO:0001501(skeletal system development);GO:0003179(heart valve morphogenesis);GO:0008285(negative regulation of cell proliferation);GO:0060412(ventricular septum morphogenesis);GO:0060539(diaphragm development);GO:0060539(diaphragm development)","NA","NA","NA","fibroblast growth factor receptor like 1 [Source:HGNC Symbol;Acc:HGNC:3693]",{"v":2.03655281881785,"d":"2.04"},{"v":0.492084982147165,"d":"0.49"},{"v":4.13862014225988,"d":"4.14"},{"v":2.04914983880093,"d":"2.05"},{"v":0.00263423690385841,"d":"0.00"},{"v":0.134413054221453,"d":"0.13"},"up","yes"]
["ENSG00000171365","CLCN5","ENST00000376088;ENST00000307367;ENST00000376091","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005794(Golgi apparatus);GO:0055085(transmembrane transport);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0005829(cytosol);GO:0005216(ion channel activity);GO:0005765(lysosomal membrane);GO:0005886(plasma membrane);GO:1903959(regulation of anion transmembrane transport);GO:0006811(ion transport);GO:0015297(antiporter activity);GO:0000139(Golgi membrane);GO:1902476(chloride transmembrane transport);GO:0006821(chloride transport);GO:0005247(voltage-gated chloride channel activity);GO:0005768(endosome);GO:0034220(ion transmembrane transport);GO:0010008(endosome membrane);GO:0005254(chloride channel activity);GO:0005887(integral component of plasma membrane);GO:0007588(excretion);GO:0045177(apical part of cell);GO:0045177(apical part of cell)","NA","NA","NA","chloride voltage-gated channel 5 [Source:HGNC Symbol;Acc:HGNC:2023]",{"v":0.343713882663151,"d":"0.34"},{"v":0.07928214709483,"d":"0.08"},{"v":4.33532510480616,"d":"4.34"},{"v":2.11614018479776,"d":"2.12"},{"v":0.00267967513557652,"d":"0.00"},{"v":0.136154632838027,"d":"0.14"},"up","yes"]
["ENSG00000102780","DGKH","ENST00000261491;ENST00000498255;ENST00000611224;ENST00000379274","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0035556(intracellular signal transduction);GO:0008152(metabolic process);GO:0003951(NAD+ kinase activity);GO:0005886(plasma membrane);GO:0004143(diacylglycerol kinase activity);GO:0007205(protein kinase C-activating G-protein coupled receptor signaling pathway);GO:0005768(endosome);GO:0030168(platelet activation);GO:0051259(protein oligomerization);GO:0046473(phosphatidic acid metabolic process);GO:0005622(intracellular);GO:0005622(intracellular)","00561(Glycerolipid metabolism);00564(Glycerophospholipid metabolism);04070(Phosphatidylinositol signaling system);04072(Phospholipase D signaling pathway);05231(Choline metabolism in cancer);05231(Choline metabolism in cancer)","K00901","EC:2.7.1.107","diacylglycerol kinase eta [Source:HGNC Symbol;Acc:HGNC:2854]",{"v":0.032471009981158,"d":"0.03"},{"v":0.150707859296227,"d":"0.15"},{"v":0.21545664660616,"d":"0.22"},{"v":-2.21453049015994,"d":"-2.21"},{"v":0.00270713351877604,"d":"0.00"},{"v":0.136971856441601,"d":"0.14"},"down","yes"]
["ENSG00000164211","STARD4","ENST00000511137;ENST00000296632;ENST00000508215;ENST00000502322;ENST00000511569;ENST00000502931;ENST00000505803;ENST00000511436;ENST00000509887","GO:0006810(transport);GO:0008289(lipid binding);GO:0006869(lipid transport);GO:0005739(mitochondrion);GO:0015485(cholesterol binding);GO:0017127(cholesterol transporter activity);GO:0032367(intracellular cholesterol transport);GO:0010873(positive regulation of cholesterol esterification);GO:0070508(cholesterol import);GO:0070859(positive regulation of bile acid biosynthetic process);GO:0010879(cholesterol transport involved in cholesterol storage);GO:0031410(cytoplasmic vesicle);GO:0031410(cytoplasmic vesicle)","NA","NA","NA","StAR related lipid transfer domain containing 4 [Source:HGNC Symbol;Acc:HGNC:18058]",{"v":0.643942492962702,"d":"0.64"},{"v":0.149258989619986,"d":"0.15"},{"v":4.31426270941658,"d":"4.31"},{"v":2.10911402954257,"d":"2.11"},{"v":2.85847811938687E-3,"d":"0.00"},{"v":0.144024240642915,"d":"0.14"},"up","yes"]
["ENSG00000177427","MIEF2","ENST00000323019;ENST00000395703;ENST00000395706;ENST00000583745;ENST00000578621;ENST00000578174","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005739(mitochondrion);GO:0005515(protein binding);GO:0005741(mitochondrial outer membrane);GO:0090314(positive regulation of protein targeting to membrane);GO:0007005(mitochondrion organization);GO:0032464(positive regulation of protein homooligomerization);GO:0090141(positive regulation of mitochondrial fission);GO:0090141(positive regulation of mitochondrial fission)","NA","NA","NA","mitochondrial elongation factor 2 [Source:HGNC Symbol;Acc:HGNC:17920]",{"v":0.970495568657092,"d":"0.97"},{"v":0.223893226001512,"d":"0.22"},{"v":4.33463569215148,"d":"4.33"},{"v":2.11591074610861,"d":"2.12"},{"v":0.00287338144605852,"d":"0.00"},{"v":0.144171914055986,"d":"0.14"},"up","yes"]
["ENSG00000161558","TMEM143","ENST00000601522;ENST00000597370;ENST00000598258;ENST00000435956;ENST00000293261;ENST00000599220;ENST00000595720;ENST00000593914;ENST00000600816","GO:0003674(molecular_function);GO:0008150(biological_process);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005739(mitochondrion);GO:0005739(mitochondrion)","NA","NA","NA","transmembrane protein 143 [Source:HGNC Symbol;Acc:HGNC:25603]",{"v":0.888355786814375,"d":"0.89"},{"v":0.204577209402864,"d":"0.20"},{"v":4.34239859565676,"d":"4.34"},{"v":2.11849215929807,"d":"2.12"},{"v":2.89396704461943E-3,"d":"0.00"},{"v":0.144602286934884,"d":"0.14"},"up","yes"]
["ENSG00000257093","KIAA1147","ENST00000536163","GO:0005737(cytoplasm);GO:0051179(localization)","NA","NA","NA","KIAA1147 [Source:HGNC Symbol;Acc:HGNC:29472]",{"v":5.05249884502447,"d":"5.05"},{"v":1.26282294290375,"d":"1.26"},{"v":4.00095585324629,"d":"4.00"},{"v":2.00034470999968,"d":"2.00"},{"v":0.00291993705977615,"d":"0.00"},{"v":0.145297033362911,"d":"0.15"},"up","yes"]
["MSTRG.14125","GIMAP4","ENST00000255945;ENST00000461940;ENST00000479232;ENST00000478135","GO:0005737(cytoplasm);GO:0005525(GTP binding);GO:0000166(nucleotide binding);GO:0005829(cytosol);GO:0005829(cytosol)","NA","NA","NA","GTPase, IMAP family member 4 [Source:HGNC Symbol;Acc:HGNC:21872]",{"v":19.6996295458276,"d":"19.70"},{"v":81.1996054240766,"d":"81.20"},{"v":0.242607454099604,"d":"0.24"},{"v":-2.0433042170286,"d":"-2.04"},{"v":0.00295232384208271,"d":"0.00"},{"v":0.146304048174321,"d":"0.15"},"down","yes"]
["MSTRG.9701","SCAND1","ENST00000305978;ENST00000373991","GO:0005634(nucleus);GO:0006355(regulation of transcription, DNA-templated);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0005515(protein binding);GO:0042802(identical protein binding);GO:0003713(transcription coactivator activity);GO:0003713(transcription coactivator activity)","NA","NA","NA","SCAN domain containing 1 [Source:HGNC Symbol;Acc:HGNC:10566]",{"v":4.25302919839679,"d":"4.25"},{"v":1.04048392685371,"d":"1.04"},{"v":4.08754915730165,"d":"4.09"},{"v":2.03123608071931,"d":"2.03"},{"v":0.00297402273012343,"d":"0.00"},{"v":0.146775334902239,"d":"0.15"},"up","yes"]
["MSTRG.1659","NAMPTP1","ENST00000440465","NA","NA","NA","NA","nicotinamide phosphoribosyltransferase pseudogene 1 [Source:HGNC Symbol;Acc:HGNC:17633]",{"v":18.436943,"d":"18.44"},{"v":75.489723,"d":"75.49"},{"v":0.244231165081901,"d":"0.24"},{"v":-2.03368078792683,"d":"-2.03"},{"v":0.0030765988624204,"d":"0.00"},{"v":0.151217973474557,"d":"0.15"},"down","yes"]
["MSTRG.64","CPTP","ENST00000343938;ENST00000488011;ENST00000464957","GO:0006810(transport);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005829(cytosol);GO:0005794(Golgi apparatus);GO:0005886(plasma membrane);GO:0006869(lipid transport);GO:0120013(intermembrane lipid transfer activity);GO:0120009(intermembrane lipid transfer);GO:0008289(lipid binding);GO:0005768(endosome);GO:0006687(glycosphingolipid metabolic process);GO:0010008(endosome membrane);GO:0005543(phospholipid binding);GO:0005548(phospholipid transporter activity);GO:0005640(nuclear outer membrane);GO:1902387(ceramide 1-phosphate binding);GO:1902388(ceramide 1-phosphate transporter activity);GO:1902389(ceramide 1-phosphate transport);GO:1902389(ceramide 1-phosphate transport)","NA","NA","NA","ceramide-1-phosphate transfer protein [Source:HGNC Symbol;Acc:HGNC:28116]",{"v":4.27720257159624,"d":"4.28"},{"v":1.06164182276995,"d":"1.06"},{"v":4.0288565124879,"d":"4.03"},{"v":2.01037042489371,"d":"2.01"},{"v":3.10129511969827E-3,"d":"0.00"},{"v":0.151812178176449,"d":"0.15"},"up","yes"]
["MSTRG.1266","RGS2","ENST00000483295;ENST00000464302;ENST00000487236;ENST00000235382","GO:0010614(negative regulation of cardiac muscle hypertrophy);GO:0060452(positive regulation of cardiac muscle contraction);GO:0071877(regulation of adrenergic receptor signaling pathway);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005829(cytosol);GO:0005739(mitochondrion);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0005096(GTPase activator activity);GO:0007049(cell cycle);GO:0048487(beta-tubulin binding);GO:0007283(spermatogenesis);GO:0010519(negative regulation of phospholipase activity);GO:0031116(positive regulation of microtubule polymerization);GO:0043407(negative regulation of MAP kinase activity);GO:0043547(positive regulation of GTPase activity);GO:0043951(negative regulation of cAMP-mediated signaling);GO:0045744(negative regulation of G-protein coupled receptor protein signaling pathway);GO:0050873(brown fat cell differentiation);GO:0055119(relaxation of cardiac muscle);GO:0060087(relaxation of vascular smooth muscle);GO:0009898(cytoplasmic side of plasma membrane);GO:0043005(neuron projection);GO:0005730(nucleolus);GO:0006417(regulation of translation);GO:0009968(negative regulation of signal transduction);GO:0008277(regulation of G-protein coupled receptor protein signaling pathway);GO:0005516(calmodulin binding);GO:0001965(G-protein alpha-subunit binding);GO:0001965(G-protein alpha-subunit binding)","04022(cGMP - PKG signaling pathway);04921(Oxytocin signaling pathway);04740(Olfactory transduction);04740(Olfactory transduction)","K18154","NA","regulator of G protein signaling 2 [Source:HGNC Symbol;Acc:HGNC:9998]",{"v":82.6002718554389,"d":"82.60"},{"v":337.082986564886,"d":"337.08"},{"v":0.245044321866239,"d":"0.25"},{"v":-2.02888537768602,"d":"-2.03"},{"v":0.00312991717200914,"d":"0.00"},{"v":0.152592965932526,"d":"0.15"},"down","yes"]
["MSTRG.3924","PAN3","ENST00000399613;ENST00000380958;ENST00000503791;ENST00000483842","GO:0003723(RNA binding);GO:0006397(mRNA processing);GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0005515(protein binding);GO:0000289(nuclear-transcribed mRNA poly(A) tail shortening);GO:0000932(P-body);GO:0031251(PAN complex);GO:0005829(cytosol);GO:0004535(poly(A)-specific ribonuclease activity);GO:0090503(RNA phosphodiester bond hydrolysis, exonucleolytic);GO:0000290(deadenylation-dependent decapping of nuclear-transcribed mRNA);GO:0006605(protein targeting);GO:0010606(positive regulation of cytoplasmic mRNA processing body assembly);GO:0000288(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay);GO:0000288(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)","03018(RNA degradation);03018(RNA degradation)","K12572","NA","PAN3 poly(A) specific ribonuclease subunit [Source:HGNC Symbol;Acc:HGNC:29991]",{"v":1.73818444663098,"d":"1.74"},{"v":7.11406194678841,"d":"7.11"},{"v":0.244330799989122,"d":"0.24"},{"v":-2.03309235575726,"d":"-2.03"},{"v":3.17892080054998E-3,"d":"0.00"},{"v":0.154357114033157,"d":"0.15"},"down","yes"]
["MSTRG.14868","TRIM14","ENST00000341469;ENST00000475147;ENST00000342043;ENST00000478401;ENST00000375098","GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0005622(intracellular);GO:0045087(innate immune response);GO:0003674(molecular_function);GO:0051092(positive regulation of NF-kappaB transcription factor activity);GO:0051091(positive regulation of sequence-specific DNA binding transcription factor activity);GO:0032897(negative regulation of viral transcription);GO:0032897(negative regulation of viral transcription)","NA","NA","NA","tripartite motif containing 14 [Source:HGNC Symbol;Acc:HGNC:16283]",{"v":13.1541796507588,"d":"13.15"},{"v":3.35344421393308,"d":"3.35"},{"v":3.92258788624098,"d":"3.92"},{"v":1.9718057713804,"d":"1.97"},{"v":0.00324364634583118,"d":"0.00"},{"v":0.156867426893571,"d":"0.16"},"up","yes"]
["ENSG00000131943","C19orf12","ENST00000323670;ENST00000591243;ENST00000392276;ENST00000592153;ENST00000614091;ENST00000392275;ENST00000342680;ENST00000623113","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005829(cytosol);GO:0005783(endoplasmic reticulum);GO:0005739(mitochondrion);GO:0006915(apoptotic process);GO:0006914(autophagy);GO:0031966(mitochondrial membrane);GO:0006979(response to oxidative stress);GO:0051560(mitochondrial calcium ion homeostasis);GO:0051560(mitochondrial calcium ion homeostasis)","NA","NA","NA","chromosome 19 open reading frame 12 [Source:HGNC Symbol;Acc:HGNC:25443]",{"v":0.318850291930086,"d":"0.32"},{"v":1.36192597880253,"d":"1.36"},{"v":0.234117196450305,"d":"0.23"},{"v":-2.0946971872533,"d":"-2.09"},{"v":0.00327266021244372,"d":"0.00"},{"v":0.15761085964334,"d":"0.16"},"down","yes"]
["ENSG00000169635","HIC2","ENST00000443632;ENST00000407598;ENST00000407464","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0008022(protein C-terminus binding);GO:0045892(negative regulation of transcription, DNA-templated);GO:0045892(negative regulation of transcription, DNA-templated)","NA","NA","NA","HIC ZBTB transcriptional repressor 2 [Source:HGNC Symbol;Acc:HGNC:18595]",{"v":0.143143605762571,"d":"0.14"},{"v":0.620283529574733,"d":"0.62"},{"v":0.230771250464623,"d":"0.23"},{"v":-2.11546459098891,"d":"-2.12"},{"v":0.00328519562950327,"d":"0.00"},{"v":0.15761085964334,"d":"0.16"},"down","yes"]
["MSTRG.12640","SLC22A23","ENST00000436008;ENST00000485307;ENST00000406686;ENST00000380298;ENST00000482874;ENST00000497691","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005215(transporter activity);GO:0055085(transmembrane transport);GO:0022857(transmembrane transporter activity);GO:0006810(transport);GO:0006811(ion transport);GO:0005515(protein binding);GO:0015711(organic anion transport);GO:0008514(organic anion transmembrane transporter activity);GO:0008514(organic anion transmembrane transporter activity)","NA","NA","NA","solute carrier family 22 member 23 [Source:HGNC Symbol;Acc:HGNC:21106]",{"v":0.757907588222072,"d":"0.76"},{"v":0.18761343054619,"d":"0.19"},{"v":4.03972991707263,"d":"4.04"},{"v":2.0142588424016,"d":"2.01"},{"v":3.31679495488644E-3,"d":"0.00"},{"v":0.158495416058502,"d":"0.16"},"up","yes"]
["ENSG00000258441","LINC00641","ENST00000555379;ENST00000555688","NA","NA","NA","NA","long intergenic non-protein coding RNA 641 [Source:HGNC Symbol;Acc:HGNC:27511]",{"v":0.198931806124234,"d":"0.20"},{"v":0.847035801749781,"d":"0.85"},{"v":0.234856431939815,"d":"0.23"},{"v":-2.09014899011173,"d":"-2.09"},{"v":0.00338186590330791,"d":"0.00"},{"v":0.160646184052633,"d":"0.16"},"down","yes"]
["MSTRG.13893","NAMPT","ENST00000222553;ENST00000417537;ENST00000484527;MSTRG.13893.1;ENST00000354289;ENST00000441045;ENST00000489358;ENST00000489732;ENST00000463871;ENST00000491027;ENST00000393618;ENST00000467730;ENST00000486949;ENST00000424768","GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016607(nuclear speck);GO:0016740(transferase activity);GO:0016757(transferase activity, transferring glycosyl groups);GO:0030054(cell junction);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0048511(rhythmic process);GO:0005125(cytokine activity);GO:0005615(extracellular space);GO:0009435(NAD biosynthetic process);GO:0019363(pyridine nucleotide biosynthetic process);GO:0004514(nicotinate-nucleotide diphosphorylase (carboxylating) activity);GO:0008144(drug binding);GO:0042803(protein homodimerization activity);GO:0047280(nicotinamide phosphoribosyltransferase activity);GO:0007565(female pregnancy);GO:0007623(circadian rhythm);GO:0014070(response to organic cyclic compound);GO:0032922(circadian regulation of gene expression);GO:0048661(positive regulation of smooth muscle cell proliferation);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0007165(signal transduction);GO:0007267(cell-cell signaling);GO:0051770(positive regulation of nitric-oxide synthase biosynthetic process);GO:0008284(positive regulation of cell proliferation);GO:0034356(NAD biosynthesis via nicotinamide riboside salvage pathway);GO:0034356(NAD biosynthesis via nicotinamide riboside salvage pathway)","00760(Nicotinate and nicotinamide metabolism);04621(NOD-like receptor signaling pathway);04621(NOD-like receptor signaling pathway)","K03462","EC:2.4.2.12","nicotinamide phosphoribosyltransferase [Source:HGNC Symbol;Acc:HGNC:30092]",{"v":44.3106968962274,"d":"44.31"},{"v":178.597913847215,"d":"178.60"},{"v":0.248103104575644,"d":"0.25"},{"v":-2.01098830674343,"d":"-2.01"},{"v":0.0033884845332477,"d":"0.00"},{"v":0.160646184052633,"d":"0.16"},"down","yes"]
["ENSG00000167861","HID1","ENST00000425042;ENST00000532395;ENST00000525128;ENST00000318565;ENST00000528902","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005794(Golgi apparatus);GO:0005829(cytosol);GO:0005515(protein binding);GO:0000139(Golgi membrane);GO:0006886(intracellular protein transport);GO:0070062(extracellular exosome);GO:0005881(cytoplasmic microtubule);GO:0005797(Golgi medial cisterna);GO:0000138(Golgi trans cisterna);GO:0090498(extrinsic component of Golgi membrane);GO:0031001(response to brefeldin A);GO:0031001(response to brefeldin A)","NA","NA","NA","HID1 domain containing [Source:HGNC Symbol;Acc:HGNC:15736]",{"v":0.52150895610071,"d":"0.52"},{"v":0.126333624112331,"d":"0.13"},{"v":4.12802972894219,"d":"4.13"},{"v":2.04545336069407,"d":"2.05"},{"v":0.00355994720139474,"d":"0.00"},{"v":0.167486408259931,"d":"0.17"},"up","yes"]
["MSTRG.11422","AC072022.1","ENST00000450760","NA","NA","NA","NA",null,{"v":0.823052,"d":"0.82"},{"v":3.483832,"d":"3.48"},{"v":0.23624904989678,"d":"0.24"},{"v":-2.08161956750904,"d":"-2.08"},{"v":3.56058134151655E-3,"d":"0.00"},{"v":0.167486408259931,"d":"0.17"},"down","yes"]
["ENSG00000186049","KRT73","ENST00000305748;ENST00000552855;ENST00000546934","GO:0005634(nucleus);GO:0005198(structural molecule activity);GO:0005515(protein binding);GO:0005882(intermediate filament);GO:0045095(keratin filament);GO:0003674(molecular_function);GO:0008150(biological_process);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0031424(keratinization);GO:0070268(cornification);GO:0070268(cornification)","NA","NA","NA","keratin 73 [Source:HGNC Symbol;Acc:HGNC:28928]",{"v":1.15184833484163,"d":"1.15"},{"v":0.278630377073906,"d":"0.28"},{"v":4.13396538790207,"d":"4.13"},{"v":2.04752630968472,"d":"2.05"},{"v":0.00358437935479704,"d":"0.00"},{"v":0.167949790624381,"d":"0.17"},"up","yes"]
["MSTRG.9637","ABALON","ENST00000629058","NA","NA","NA","NA","apoptotic BCL2L1-antisense long non-coding RNA [Source:HGNC Symbol;Acc:HGNC:49667]",{"v":1.632552,"d":"1.63"},{"v":6.615261,"d":"6.62"},{"v":0.246785727728657,"d":"0.25"},{"v":-2.01866913285741,"d":"-2.02"},{"v":0.00362255645885979,"d":"0.00"},{"v":0.169080716579805,"d":"0.17"},"down","yes"]
["ENSG00000197937","ZNF347","ENST00000452676;ENST00000595710;ENST00000334197;ENST00000599096;ENST00000595967","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0005622(intracellular);GO:0005622(intracellular)","NA","NA","NA","zinc finger protein 347 [Source:HGNC Symbol;Acc:HGNC:16447]",{"v":0.371646521082028,"d":"0.37"},{"v":0.0906909272806921,"d":"0.09"},{"v":4.09794598231163,"d":"4.10"},{"v":2.03490096737386,"d":"2.03"},{"v":0.00377823674016553,"d":"0.00"},{"v":0.175666126737735,"d":"0.18"},"up","yes"]
["MSTRG.1083","GPATCH4","ENST00000368232;ENST00000527691;ENST00000438976;ENST00000529520;ENST00000531129;ENST00000494414;ENST00000498641;ENST00000498756;ENST00000473910;ENST00000415314;ENST00000531900;ENST00000525375;ENST00000506832","GO:0003676(nucleic acid binding);GO:0002244(hematopoietic progenitor cell differentiation);GO:0002244(hematopoietic progenitor cell differentiation)","NA","NA","NA","G-patch domain containing 4 [Source:HGNC Symbol;Acc:HGNC:25982]",{"v":2.64873953189092,"d":"2.65"},{"v":0.674940183908046,"d":"0.67"},{"v":3.9244063326533,"d":"3.92"},{"v":1.97247442579633,"d":"1.97"},{"v":0.00380936982025262,"d":"0.00"},{"v":0.176432428367239,"d":"0.18"},"up","yes"]
["MSTRG.1393","HLX","ENST00000366903;ENST00000549319","GO:0005634(nucleus);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0043565(sequence-specific DNA binding);GO:0005515(protein binding);GO:0030154(cell differentiation);GO:0007275(multicellular organism development);GO:0001889(liver development);GO:0007519(skeletal muscle tissue development);GO:0008284(positive regulation of cell proliferation);GO:0045627(positive regulation of T-helper 1 cell differentiation);GO:0045629(negative regulation of T-helper 2 cell differentiation);GO:0046622(positive regulation of organ growth);GO:0048484(enteric nervous system development);GO:0048513(animal organ development);GO:0048557(embryonic digestive tract morphogenesis);GO:0048557(embryonic digestive tract morphogenesis)","NA","NA","NA","H2.0 like homeobox [Source:HGNC Symbol;Acc:HGNC:4978]",{"v":1.47496888021201,"d":"1.47"},{"v":5.87183202791519,"d":"5.87"},{"v":0.251193983955924,"d":"0.25"},{"v":-1.99312618249256,"d":"-1.99"},{"v":0.00387312774407996,"d":"0.00"},{"v":0.178698100744103,"d":"0.18"},"down","yes"]
["MSTRG.5098","RFX7","MSTRG.5098.2;ENST00000560792;ENST00000559447","GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0005634(nucleus);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0006357(regulation of transcription from RNA polymerase II promoter)","NA","NA","NA","regulatory factor X7 [Source:HGNC Symbol;Acc:HGNC:25777]",{"v":2.61629825729927,"d":"2.62"},{"v":0.685010932846715,"d":"0.69"},{"v":3.8193525560631,"d":"3.82"},{"v":1.9333280981243,"d":"1.93"},{"v":0.00396037026249136,"d":"0.00"},{"v":0.181362018429426,"d":"0.18"},"up","yes"]
["ENSG00000104343","UBE2W","ENST00000602593;ENST00000517608;ENST00000422906;ENST00000519277;ENST00000519255;ENST00000419880;ENST00000523278","GO:0005634(nucleus);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0016740(transferase activity);GO:0016567(protein ubiquitination);GO:0005515(protein binding);GO:0006281(DNA repair);GO:0006974(cellular response to DNA damage stimulus);GO:0005737(cytoplasm);GO:0061630(ubiquitin protein ligase activity);GO:0043161(proteasome-mediated ubiquitin-dependent protein catabolic process);GO:0005654(nucleoplasm);GO:0031625(ubiquitin protein ligase binding);GO:0006515(misfolded or incompletely synthesized protein catabolic process);GO:0004842(ubiquitin-protein transferase activity);GO:0070979(protein K11-linked ubiquitination);GO:0006513(protein monoubiquitination);GO:0071218(cellular response to misfolded protein);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005730(nucleolus);GO:0005730(nucleolus)","04120(Ubiquitin mediated proteolysis);04120(Ubiquitin mediated proteolysis)","K10688","EC:2.3.2.25","ubiquitin conjugating enzyme E2 W [Source:HGNC Symbol;Acc:HGNC:25616]",{"v":0.655694607590759,"d":"0.66"},{"v":2.60813491683168,"d":"2.61"},{"v":0.251403638423462,"d":"0.25"},{"v":-1.99192256566394,"d":"-1.99"},{"v":0.00396240384327717,"d":"0.00"},{"v":0.181362018429426,"d":"0.18"},"down","yes"]
["MSTRG.1258","PTGS2","ENST00000367468;ENST00000559800;ENST00000466691;ENST00000490885","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0046872(metal ion binding);GO:0005783(endoplasmic reticulum);GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0006629(lipid metabolic process);GO:0005789(endoplasmic reticulum membrane);GO:0006631(fatty acid metabolic process);GO:0006633(fatty acid biosynthetic process);GO:0006954(inflammatory response);GO:0051213(dioxygenase activity);GO:0020037(heme binding);GO:0008217(regulation of blood pressure);GO:0098869(cellular oxidant detoxification);GO:0004601(peroxidase activity);GO:0006979(response to oxidative stress);GO:0004666(prostaglandin-endoperoxide synthase activity);GO:0001516(prostaglandin biosynthetic process);GO:0019371(cyclooxygenase pathway);GO:0043231(intracellular membrane-bounded organelle);GO:0019899(enzyme binding);GO:0031090(organelle membrane);GO:0006928(movement of cell or subcellular component);GO:0005515(protein binding);GO:0006693(prostaglandin metabolic process);GO:0071456(cellular response to hypoxia);GO:0050473(arachidonate 15-lipoxygenase activity);GO:0019372(lipoxygenase pathway);GO:0045429(positive regulation of nitric oxide biosynthetic process);GO:0050727(regulation of inflammatory response);GO:0010575(positive regulation of vascular endothelial growth factor production);GO:0090336(positive regulation of brown fat cell differentiation);GO:0031622(positive regulation of fever generation);GO:0071636(positive regulation of transforming growth factor beta production);GO:0043005(neuron projection);GO:0090050(positive regulation of cell migration involved in sprouting angiogenesis);GO:0005788(endoplasmic reticulum lumen);GO:0008289(lipid binding);GO:0016702(oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen);GO:0042803(protein homodimerization activity);GO:0001525(angiogenesis);GO:0007566(embryo implantation);GO:0007568(aging);GO:0007612(learning);GO:0007613(memory);GO:0008284(positive regulation of cell proliferation);GO:0008285(negative regulation of cell proliferation);GO:0009314(response to radiation);GO:0009750(response to fructose);GO:0010033(response to organic substance);GO:0010042(response to manganese ion);GO:0010226(response to lithium ion);GO:0010243(response to organonitrogen compound);GO:0010942(positive regulation of cell death);GO:0014070(response to organic cyclic compound);GO:0019233(sensory perception of pain);GO:0030282(bone mineralization);GO:0030728(ovulation);GO:0031394(positive regulation of prostaglandin biosynthetic process);GO:0031915(positive regulation of synaptic plasticity);GO:0032227(negative regulation of synaptic transmission, dopaminergic);GO:0032355(response to estradiol);GO:0032496(response to lipopolysaccharide);GO:0033138(positive regulation of peptidyl-serine phosphorylation);GO:0033280(response to vitamin D);GO:0034097(response to cytokine);GO:0034356(NAD biosynthesis via nicotinamide riboside salvage pathway);GO:0034605(cellular response to heat);GO:0034612(response to tumor necrosis factor);GO:0034644(cellular response to UV);GO:0035633(maintenance of permeability of blood-brain barrier);GO:0042127(regulation of cell proliferation);GO:0042346(positive regulation of NF-kappaB import into nucleus);GO:0042493(response to drug);GO:0042633(hair cycle);GO:0043065(positive regulation of apoptotic process);GO:0043066(negative regulation of apoptotic process);GO:0043154(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process);GO:0045786(negative regulation of cell cycle);GO:0045907(positive regulation of vasoconstriction);GO:0045986(negative regulation of smooth muscle contraction);GO:0045987(positive regulation of smooth muscle contraction);GO:0046697(decidualization);GO:0048661(positive regulation of smooth muscle cell proliferation);GO:0050873(brown fat cell differentiation);GO:0051384(response to glucocorticoid);GO:0051926(negative regulation of calcium ion transport);GO:0051968(positive regulation of synaptic transmission, glutamatergic);GO:0070542(response to fatty acid);GO:0071260(cellular response to mechanical stimulus);GO:0071318(cellular response to ATP);GO:0071471(cellular response to non-ionic osmotic stress);GO:0071498(cellular response to fluid shear stress);GO:0090271(positive regulation of fibroblast growth factor production);GO:0090362(positive regulation of platelet-derived growth factor production);GO:1902219(negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress);GO:0005901(caveola);GO:0043234(protein complex);GO:0043234(protein complex)","00590(Arachidonic acid metabolism);04370(VEGF signaling pathway);04064(NF-kappa B signaling pathway);04668(TNF signaling pathway);04657(IL-17 signaling pathway);04923(Regulation of lipolysis in adipocyte);04913(Ovarian Steroidogenesis);04921(Oxytocin signaling pathway);04726(Serotonergic synapse);04723(Retrograde endocannabinoid signaling);05200(Pathways in cancer);05206(MicroRNAs in cancer);05204(Chemical carcinogenesis);05222(Small cell lung cancer);05167(Kaposi's sarcoma-associated herpesvirus infection);05165(Human papillomavirus infection);05140(Leishmaniasis);05140(Leishmaniasis)","K11987","EC:1.14.99.1","prostaglandin-endoperoxide synthase 2 [Source:HGNC Symbol;Acc:HGNC:9605]",{"v":1.24411398026191,"d":"1.24"},{"v":4.93925477282217,"d":"4.94"},{"v":0.251882933252915,"d":"0.25"},{"v":-1.98917472170572,"d":"-1.99"},{"v":0.00397604823661921,"d":"0.00"},{"v":0.181362018429426,"d":"0.18"},"down","yes"]
["MSTRG.6809","KRT23","ENST00000209718;ENST00000582754;ENST00000584517","GO:0005198(structural molecule activity);GO:0005882(intermediate filament);GO:0005829(cytosol);GO:0031424(keratinization);GO:0070268(cornification);GO:0070268(cornification)","NA","NA","NA","keratin 23 [Source:HGNC Symbol;Acc:HGNC:6438]",{"v":5.01105733080634,"d":"5.01"},{"v":19.7600050599586,"d":"19.76"},{"v":0.253595953826989,"d":"0.25"},{"v":-1.97939636770777,"d":"-1.98"},{"v":3.99390444637872E-3,"d":"0.00"},{"v":0.181489046578463,"d":"0.18"},"down","yes"]
["ENSG00000215012","RTL10","ENST00000405640;ENST00000416337;ENST00000407472;ENST00000328554","GO:0005739(mitochondrion);GO:0006915(apoptotic process);GO:0005515(protein binding);GO:0051881(regulation of mitochondrial membrane potential);GO:0097345(mitochondrial outer membrane permeabilization);GO:0097345(mitochondrial outer membrane permeabilization)","NA","NA","NA","retrotransposon Gag like 10 [Source:HGNC Symbol;Acc:HGNC:26112]",{"v":0.397866392767897,"d":"0.40"},{"v":1.5958591781567,"d":"1.60"},{"v":0.249311717608726,"d":"0.25"},{"v":-2.00397740404058,"d":"-2.00"},{"v":0.00404566952811007,"d":"0.00"},{"v":0.183150197208652,"d":"0.18"},"down","yes"]
["MSTRG.8092","ZNF420","ENST00000337995;ENST00000590332;ENST00000586540;ENST00000589245;ENST00000587082;ENST00000585862","GO:0003676(nucleic acid binding);GO:0006355(regulation of transcription, DNA-templated);GO:0005622(intracellular);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0005654(nucleoplasm);GO:0070062(extracellular exosome);GO:0042981(regulation of apoptotic process);GO:0042981(regulation of apoptotic process)","NA","NA","NA","zinc finger protein 420 [Source:HGNC Symbol;Acc:HGNC:20649]",{"v":0.167057718866518,"d":"0.17"},{"v":0.712128697986577,"d":"0.71"},{"v":0.234589224305726,"d":"0.23"},{"v":-2.09179134920096,"d":"-2.09"},{"v":0.00411788264271831,"d":"0.00"},{"v":0.185439015879764,"d":"0.19"},"down","yes"]
["MSTRG.7922","CYP4F3","ENST00000221307;ENST00000609670;ENST00000592279;ENST00000585846;ENST00000592424;ENST00000591058;ENST00000586182","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0046872(metal ion binding);GO:0004497(monooxygenase activity);GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0006629(lipid metabolic process);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005506(iron ion binding);GO:0016705(oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen);GO:0020037(heme binding);GO:0043231(intracellular membrane-bounded organelle);GO:0031090(organelle membrane);GO:0019825(oxygen binding);GO:0006691(leukotriene metabolic process);GO:0006690(icosanoid metabolic process);GO:0050051(leukotriene-B4 20-monooxygenase activity);GO:0052870(tocopherol omega-hydroxylase activity);GO:0052871(alpha-tocopherol omega-hydroxylase activity);GO:0097258(20-hydroxy-leukotriene B4 omega oxidase activity);GO:0097259(20-aldehyde-leukotriene B4 20-monooxygenase activity);GO:0036101(leukotriene B4 catabolic process);GO:0036101(leukotriene B4 catabolic process)","00590(Arachidonic acid metabolism);00590(Arachidonic acid metabolism)","K17726","EC:1.14.13.30;EC:1.14.13.194","cytochrome P450 family 4 subfamily F member 3 [Source:HGNC Symbol;Acc:HGNC:2646]",{"v":3.53871032553924,"d":"3.54"},{"v":13.8722579505166,"d":"13.87"},{"v":0.255092598347154,"d":"0.26"},{"v":-1.97090705593433,"d":"-1.97"},{"v":0.00412702676098462,"d":"0.00"},{"v":0.185439015879764,"d":"0.19"},"down","yes"]
["ENSG00000241978","AKAP2","ENST00000374525;ENST00000485762;ENST00000482335","NA","NA","NA","NA","A-kinase anchoring protein 2 [Source:HGNC Symbol;Acc:HGNC:372]",{"v":2.97836462045281,"d":"2.98"},{"v":0.784440930679217,"d":"0.78"},{"v":3.79679910107949,"d":"3.80"},{"v":1.92478366407573,"d":"1.92"},{"v":0.00418528263567061,"d":"0.00"},{"v":0.186718958458379,"d":"0.19"},"up","yes"]
["MSTRG.965","S100A8","ENST00000368733;ENST00000477801;ENST00000368732","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0005509(calcium ion binding);GO:0005829(cytosol);GO:0045111(intermediate filament cytoskeleton);GO:0005886(plasma membrane);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0008017(microtubule binding);GO:0006915(apoptotic process);GO:0005615(extracellular space);GO:0006914(autophagy);GO:0002376(immune system process);GO:0045087(innate immune response);GO:0006935(chemotaxis);GO:0006954(inflammatory response);GO:0042742(defense response to bacterium);GO:0050727(regulation of inflammatory response);GO:0001816(cytokine production);GO:0030593(neutrophil chemotaxis);GO:0070062(extracellular exosome);GO:0043312(neutrophil degranulation);GO:0051092(positive regulation of NF-kappaB transcription factor activity);GO:0002224(toll-like receptor signaling pathway);GO:0034774(secretory granule lumen);GO:0019730(antimicrobial humoral response);GO:0050729(positive regulation of inflammatory response);GO:2001244(positive regulation of intrinsic apoptotic signaling pathway);GO:0030307(positive regulation of cell growth);GO:0006919(activation of cysteine-type endopeptidase activity involved in apoptotic process);GO:0051493(regulation of cytoskeleton organization);GO:0032602(chemokine production);GO:0050832(defense response to fungus);GO:0050786(RAGE receptor binding);GO:0035662(Toll-like receptor 4 binding);GO:0050544(arachidonic acid binding);GO:0002523(leukocyte migration involved in inflammatory response);GO:0018119(peptidyl-cysteine S-nitrosylation);GO:0032119(sequestering of zinc ion);GO:0070488(neutrophil aggregation);GO:0002526(acute inflammatory response);GO:0002544(chronic inflammatory response);GO:0002793(positive regulation of peptide secretion);GO:0010043(response to zinc ion);GO:0014002(astrocyte development);GO:0032496(response to lipopolysaccharide);GO:0042060(wound healing);GO:0045471(response to ethanol);GO:0045471(response to ethanol)","04657(IL-17 signaling pathway);04657(IL-17 signaling pathway)","K21127","NA","S100 calcium binding protein A8 [Source:HGNC Symbol;Acc:HGNC:10498]",{"v":72.1048061918489,"d":"72.10"},{"v":281.30282900497,"d":"281.30"},{"v":0.256324497150987,"d":"0.26"},{"v":-1.9639567300723,"d":"-1.96"},{"v":0.00418652373225064,"d":"0.00"},{"v":0.186718958458379,"d":"0.19"},"down","yes"]
["MSTRG.3111","CLEC4D","ENST00000299665","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0030246(carbohydrate binding);GO:0005515(protein binding);GO:0002376(immune system process);GO:0045087(innate immune response);GO:0002250(adaptive immune response);GO:0005886(plasma membrane);GO:0002223(stimulatory C-type lectin receptor signaling pathway);GO:0043312(neutrophil degranulation);GO:0035579(specific granule membrane);GO:0070821(tertiary granule membrane);GO:0101003(ficolin-1-rich granule membrane);GO:0034987(immunoglobulin receptor binding);GO:0002292(T cell differentiation involved in immune response);GO:0038094(Fc-gamma receptor signaling pathway);GO:0042742(defense response to bacterium)","NA","NA","NA","C-type lectin domain family 4 member D [Source:HGNC Symbol;Acc:HGNC:14554]",{"v":0.614202491803279,"d":"0.61"},{"v":2.50769320218579,"d":"2.51"},{"v":0.244927286666455,"d":"0.24"},{"v":-2.02957458539769,"d":"-2.03"},{"v":0.00420979644341462,"d":"0.00"},{"v":0.187064091408114,"d":"0.19"},"down","yes"]
["ENSG00000159556","ISL2","ENST00000290759;ENST00000558437","GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0043565(sequence-specific DNA binding);GO:0007275(multicellular organism development);GO:0048666(neuron development);GO:0048935(peripheral nervous system neuron development);GO:0021520(spinal cord motor neuron cell fate specification);GO:0021524(visceral motor neuron differentiation);GO:0031290(retinal ganglion cell axon guidance);GO:0045665(negative regulation of neuron differentiation);GO:0048663(neuron fate commitment);GO:0048663(neuron fate commitment)","NA","NA","NA","ISL LIM homeobox 2 [Source:HGNC Symbol;Acc:HGNC:18524]",{"v":0.348922755965781,"d":"0.35"},{"v":1.46909826429536,"d":"1.47"},{"v":0.237508112592549,"d":"0.24"},{"v":-2.07395130229788,"d":"-2.07"},{"v":0.00426991177237894,"d":"0.00"},{"v":0.189037785158041,"d":"0.19"},"down","yes"]
["ENSG00000115902","SLC1A4","ENST00000234256;ENST00000480594;ENST00000493121","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0015293(symporter activity);GO:0055085(transmembrane transport);GO:0003333(amino acid transmembrane transport);GO:0042470(melanosome);GO:0005882(intermediate filament);GO:0005254(chloride channel activity);GO:1902476(chloride transmembrane transport);GO:0005886(plasma membrane);GO:0005887(integral component of plasma membrane);GO:0006821(chloride transport);GO:0070062(extracellular exosome);GO:0009986(cell surface);GO:0015171(amino acid transmembrane transporter activity);GO:0050890(cognition);GO:0015184(L-cystine transmembrane transporter activity);GO:0015811(L-cystine transport);GO:0006865(amino acid transport);GO:0015180(L-alanine transmembrane transporter activity);GO:0015186(L-glutamine transmembrane transporter activity);GO:0015193(L-proline transmembrane transporter activity);GO:0015194(L-serine transmembrane transporter activity);GO:0015195(L-threonine transmembrane transporter activity);GO:0034590(L-hydroxyproline transmembrane transporter activity);GO:0006868(glutamine transport);GO:0015808(L-alanine transport);GO:0015824(proline transport);GO:0015825(L-serine transport);GO:0015826(threonine transport);GO:0034589(hydroxyproline transport);GO:0035249(synaptic transmission, glutamatergic);GO:0035524(proline transmembrane transport);GO:0015175(neutral amino acid transmembrane transporter activity);GO:0030425(dendrite);GO:0043025(neuronal cell body);GO:0043025(neuronal cell body)","NA","NA","NA","solute carrier family 1 member 4 [Source:HGNC Symbol;Acc:HGNC:10942]",{"v":1.46916857011097,"d":"1.47"},{"v":0.385187411154345,"d":"0.39"},{"v":3.81416559203767,"d":"3.81"},{"v":1.93136747963011,"d":"1.93"},{"v":0.00432889442387182,"d":"0.00"},{"v":0.190870535021152,"d":"0.19"},"up","yes"]
["ENSG00000132846","ZBED3","ENST00000255198;ENST00000505685","GO:0003676(nucleic acid binding);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0046872(metal ion binding);GO:0003677(DNA binding);GO:0005829(cytosol);GO:0016055(Wnt signaling pathway);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0050821(protein stabilization);GO:0001933(negative regulation of protein phosphorylation);GO:0090263(positive regulation of canonical Wnt signaling pathway);GO:1903955(positive regulation of protein targeting to mitochondrion);GO:1903955(positive regulation of protein targeting to mitochondrion)","NA","NA","NA","zinc finger BED-type containing 3 [Source:HGNC Symbol;Acc:HGNC:20711]",{"v":1.07948981148296,"d":"1.08"},{"v":0.280352719680688,"d":"0.28"},{"v":3.85047026728495,"d":"3.85"},{"v":1.94503465641733,"d":"1.95"},{"v":0.00434301001459855,"d":"0.00"},{"v":0.190870535021152,"d":"0.19"},"up","yes"]
["MSTRG.3496","CTDSP2","ENST00000398073;ENST00000549039;ENST00000550144;ENST00000551594;ENST00000548823;ENST00000547169;ENST00000547701;ENST00000552294","GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0016787(hydrolase activity);GO:0016791(phosphatase activity);GO:0016311(dephosphorylation);GO:0004721(phosphoprotein phosphatase activity);GO:0005515(protein binding);GO:0001933(negative regulation of protein phosphorylation);GO:2000134(negative regulation of G1/S transition of mitotic cell cycle);GO:0005654(nucleoplasm);GO:0006470(protein dephosphorylation);GO:0008420(CTD phosphatase activity);GO:0036498(IRE1-mediated unfolded protein response);GO:0036498(IRE1-mediated unfolded protein response)","NA","NA","NA","CTD small phosphatase 2 [Source:HGNC Symbol;Acc:HGNC:17077]",{"v":12.5107366187064,"d":"12.51"},{"v":48.4268526449835,"d":"48.43"},{"v":0.258342963364198,"d":"0.26"},{"v":-1.9526405061036,"d":"-1.95"},{"v":0.00441214539462753,"d":"0.00"},{"v":0.192400954443489,"d":"0.19"},"down","yes"]
["MSTRG.14349","CEBPD","ENST00000408965;MSTRG.14349.1","GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0005515(protein binding);GO:0006366(transcription from RNA polymerase II promoter);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:0001077(transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0042803(protein homodimerization activity);GO:0043565(sequence-specific DNA binding);GO:0044212(transcription regulatory region DNA binding);GO:0046982(protein heterodimerization activity);GO:0002244(hematopoietic progenitor cell differentiation);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0045444(fat cell differentiation);GO:0045669(positive regulation of osteoblast differentiation);GO:0045892(negative regulation of transcription, DNA-templated);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0048839(inner ear development)","NA","NA","NA","CCAAT/enhancer binding protein delta [Source:HGNC Symbol;Acc:HGNC:1835]",{"v":4.69839131292517,"d":"4.70"},{"v":18.227631170068,"d":"18.23"},{"v":0.25776203551016,"d":"0.26"},{"v":-1.95588830292756,"d":"-1.96"},{"v":4.41673386042633E-3,"d":"0.00"},{"v":0.192400954443489,"d":"0.19"},"down","yes"]
["ENSG00000163235","TGFA","ENST00000295400;ENST00000394241;ENST00000460808;ENST00000445399;ENST00000418333;ENST00000444975","GO:0005615(extracellular space);GO:0048471(perinuclear region of cytoplasm);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0008083(growth factor activity);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0005887(integral component of plasma membrane);GO:0000139(Golgi membrane);GO:0005789(endoplasmic reticulum membrane);GO:0009986(cell surface);GO:0006888(ER to Golgi vesicle-mediated transport);GO:0031410(cytoplasmic vesicle);GO:0008283(cell proliferation);GO:0048208(COPII vesicle coating);GO:0012507(ER to Golgi transport vesicle membrane);GO:0033116(endoplasmic reticulum-Golgi intermediate compartment membrane);GO:0051781(positive regulation of cell division);GO:0005154(epidermal growth factor receptor binding);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0016323(basolateral plasma membrane);GO:0045741(positive regulation of epidermal growth factor-activated receptor activity);GO:0045840(positive regulation of mitotic nuclear division);GO:0000187(activation of MAPK activity);GO:0050679(positive regulation of epithelial cell proliferation);GO:0001525(angiogenesis);GO:0007173(epidermal growth factor receptor signaling pathway);GO:0008284(positive regulation of cell proliferation);GO:0042060(wound healing);GO:0042493(response to drug);GO:0043066(negative regulation of apoptotic process);GO:0048523(negative regulation of cellular process);GO:0050731(positive regulation of peptidyl-tyrosine phosphorylation);GO:0060749(mammary gland alveolus development);GO:0072574(hepatocyte proliferation);GO:0005634(nucleus);GO:0005634(nucleus)","04014(Ras signaling pathway);04010(MAPK signaling pathway);04012(ErbB signaling pathway);04151(PI3K-Akt signaling pathway);05200(Pathways in cancer);05212(Pancreatic cancer);05225(Hepatocellular carcinoma);05214(Glioma);05211(Renal cell carcinoma);05215(Prostate cancer);05223(Non-small cell lung cancer);01521(EGFR tyrosine kinase inhibitor resistance);01521(EGFR tyrosine kinase inhibitor resistance)","K08774","NA","transforming growth factor alpha [Source:HGNC Symbol;Acc:HGNC:11765]",{"v":0.746224831754987,"d":"0.75"},{"v":2.93611450292162,"d":"2.94"},{"v":0.254153859126559,"d":"0.25"},{"v":-1.97622595774461,"d":"-1.98"},{"v":4.42576518691634E-3,"d":"0.00"},{"v":0.192400954443489,"d":"0.19"},"down","yes"]
["MSTRG.13902","HBP1","ENST00000498408;ENST00000478930;ENST00000463202;ENST00000607681;ENST00000464009;MSTRG.13902.5;ENST00000468410;ENST00000485846;ENST00000479011;ENST00000483809;ENST00000468116;ENST00000497535;ENST00000468401;ENST00000463790;ENST00000222574","GO:0003723(RNA binding);GO:0005634(nucleus);GO:0016607(nuclear speck);GO:0005654(nucleoplasm);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0016055(Wnt signaling pathway);GO:0007050(cell cycle arrest);GO:0007050(cell cycle arrest)","NA","NA","NA","HMG-box transcription factor 1 [Source:HGNC Symbol;Acc:HGNC:23200]",{"v":2.71740868753875,"d":"2.72"},{"v":10.5353022481401,"d":"10.54"},{"v":0.257933623880462,"d":"0.26"},{"v":-1.95492824171496,"d":"-1.95"},{"v":0.00448351407168942,"d":"0.00"},{"v":0.194210346947065,"d":"0.19"},"down","yes"]
["MSTRG.6713","CCL4","ENST00000615863;ENST00000613947;ENST00000621626","GO:0005576(extracellular region);GO:0005515(protein binding);GO:0006955(immune response);GO:0005125(cytokine activity);GO:0005615(extracellular space);GO:0008009(chemokine activity);GO:0006935(chemotaxis);GO:0006954(inflammatory response);GO:0042802(identical protein binding);GO:0007186(G-protein coupled receptor signaling pathway);GO:0002548(monocyte chemotaxis);GO:0030593(neutrophil chemotaxis);GO:0043547(positive regulation of GTPase activity);GO:0070098(chemokine-mediated signaling pathway);GO:0070374(positive regulation of ERK1 and ERK2 cascade);GO:0071346(cellular response to interferon-gamma);GO:0071347(cellular response to interleukin-1);GO:0071356(cellular response to tumor necrosis factor);GO:0007165(signal transduction);GO:0007267(cell-cell signaling);GO:0007155(cell adhesion);GO:0006928(movement of cell or subcellular component);GO:0009615(response to virus);GO:0051928(positive regulation of calcium ion transport);GO:0009636(response to toxic substance);GO:0043922(negative regulation by host of viral transcription);GO:0031726(CCR1 chemokine receptor binding);GO:0031730(CCR5 chemokine receptor binding);GO:0050850(positive regulation of calcium-mediated signaling);GO:2000503(positive regulation of natural killer cell chemotaxis);GO:0007163(establishment or maintenance of cell polarity);GO:0035690(cellular response to drug);GO:0035690(cellular response to drug)","04064(NF-kappa B signaling pathway);04060(Cytokine-cytokine receptor interaction);04620(Toll-like receptor signaling pathway);04623(Cytosolic DNA-sensing pathway);04062(Chemokine signaling pathway);05132(Salmonella infection);05132(Salmonella infection)","K12964","NA","C-C motif chemokine ligand 4 [Source:HGNC Symbol;Acc:HGNC:10630]",{"v":2.86013227362205,"d":"2.86"},{"v":11.1378264173228,"d":"11.14"},{"v":0.256794473755997,"d":"0.26"},{"v":-1.96131393904165,"d":"-1.96"},{"v":0.00451377034201828,"d":"0.00"},{"v":0.194470801307706,"d":"0.19"},"down","yes"]
["MSTRG.3681","FICD","ENST00000552695;ENST00000552758;ENST00000546448;ENST00000361549","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0016740(transferase activity);GO:0016779(nucleotidyltransferase activity);GO:0034260(negative regulation of GTPase activity);GO:0070733(protein adenylyltransferase activity);GO:0018117(protein adenylylation);GO:0018117(protein adenylylation)","NA","NA","NA","FIC domain containing [Source:HGNC Symbol;Acc:HGNC:18416]",{"v":0.80923745605812,"d":"0.81"},{"v":0.203738647761894,"d":"0.20"},{"v":3.97193887830188,"d":"3.97"},{"v":1.98984342230002,"d":"1.99"},{"v":0.00454402271534243,"d":"0.00"},{"v":0.194470801307706,"d":"0.19"},"up","yes"]
["ENSG00000198105","ZNF248","ENST00000395867;ENST00000611278;ENST00000615949;ENST00000485560;ENST00000374648","GO:0003676(nucleic acid binding);GO:0006355(regulation of transcription, DNA-templated);GO:0005622(intracellular);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0003677(DNA binding)","NA","NA","NA","zinc finger protein 248 [Source:HGNC Symbol;Acc:HGNC:13041]",{"v":0.12966803306352,"d":"0.13"},{"v":0.53581556180546,"d":"0.54"},{"v":0.24200124503028,"d":"0.24"},{"v":-2.04691362509663,"d":"-2.05"},{"v":0.00454588900158165,"d":"0.00"},{"v":0.194470801307706,"d":"0.19"},"down","yes"]
["MSTRG.14373","SDCBP","ENST00000447182;ENST00000260130;MSTRG.14373.11;MSTRG.14373.3;ENST00000413219;ENST00000630925;ENST00000519115;ENST00000520168;ENST00000424270;ENST00000520228;ENST00000447267;ENST00000523441;ENST00000522243;ENST00000523483;ENST00000522843","GO:0005737(cytoplasm);GO:0005634(nucleus);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0043231(intracellular membrane-bounded organelle);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0035556(intracellular signal transduction);GO:0031965(nuclear membrane);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005886(plasma membrane);GO:0030036(actin cytoskeleton organization);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0042470(melanosome);GO:0005615(extracellular space);GO:0030054(cell junction);GO:0045121(membrane raft);GO:0007268(chemical synaptic transmission);GO:0005925(focal adhesion);GO:0042802(identical protein binding);GO:0008289(lipid binding);GO:0045296(cadherin binding);GO:0006930(substrate-dependent cell migration, cell extension);GO:0070062(extracellular exosome);GO:0072562(blood microparticle);GO:0030335(positive regulation of cell migration);GO:0005912(adherens junction);GO:0005546(phosphatidylinositol-4,5-bisphosphate binding);GO:0043312(neutrophil degranulation);GO:0007346(regulation of mitotic cell cycle);GO:0008284(positive regulation of cell proliferation);GO:0032435(negative regulation of proteasomal ubiquitin-dependent protein catabolic process);GO:0006612(protein targeting to membrane);GO:0047485(protein N-terminus binding);GO:0030511(positive regulation of transforming growth factor beta receptor signaling pathway);GO:0046982(protein heterodimerization activity);GO:0048013(ephrin receptor signaling pathway);GO:0005109(frizzled binding);GO:0005137(interleukin-5 receptor binding);GO:0008093(cytoskeletal adaptor activity);GO:0045545(syndecan binding);GO:0002091(negative regulation of receptor internalization);GO:0010718(positive regulation of epithelial to mesenchymal transition);GO:0010862(positive regulation of pathway-restricted SMAD protein phosphorylation);GO:0030307(positive regulation of cell growth);GO:0042327(positive regulation of phosphorylation);GO:0046330(positive regulation of JNK cascade);GO:1903543(positive regulation of exosomal secretion);GO:1903553(positive regulation of extracellular exosome assembly);GO:0005895(interleukin-5 receptor complex);GO:0035578(azurophil granule lumen);GO:1903561(extracellular vesicle);GO:0008022(protein C-terminus binding);GO:0019838(growth factor binding);GO:0042043(neurexin family protein binding);GO:0042803(protein homodimerization activity);GO:0046875(ephrin receptor binding);GO:0050839(cell adhesion molecule binding);GO:0007265(Ras protein signal transduction);GO:0005622(intracellular);GO:0005622(intracellular)","NA","NA","NA","syndecan binding protein [Source:HGNC Symbol;Acc:HGNC:10662]",{"v":13.1738540840546,"d":"13.17"},{"v":50.7498640617426,"d":"50.75"},{"v":0.259584027023742,"d":"0.26"},{"v":-1.94572648213047,"d":"-1.95"},{"v":0.00455412439534739,"d":"0.00"},{"v":0.194470801307706,"d":"0.19"},"down","yes"]
["MSTRG.3437","TMEM198B","ENST00000478241;ENST00000484016;ENST00000637092;ENST00000637087;ENST00000637951;ENST00000471276;ENST00000508246;ENST00000636428;ENST00000487582;ENST00000482378;ENST00000635977;ENST00000636659;ENST00000636790;ENST00000635938","NA","NA","NA","NA","transmembrane protein 198B (pseudogene) [Source:HGNC Symbol;Acc:HGNC:43629]",{"v":1.76292913699929,"d":"1.76"},{"v":0.456980062337047,"d":"0.46"},{"v":3.85778129571665,"d":"3.86"},{"v":1.94777135683216,"d":"1.95"},{"v":0.00460394389850268,"d":"0.00"},{"v":0.195903506804839,"d":"0.20"},"up","yes"]
["ENSG00000196663","TECPR2","ENST00000359520;ENST00000561228;ENST00000558678;ENST00000559124;ENST00000561099","GO:0005515(protein binding);GO:0006914(autophagy);GO:0006914(autophagy)","NA","NA","NA","tectonin beta-propeller repeat containing 2 [Source:HGNC Symbol;Acc:HGNC:19957]",{"v":1.21192025799233,"d":"1.21"},{"v":4.67122863150043,"d":"4.67"},{"v":0.259443575469577,"d":"0.26"},{"v":-1.94650728363178,"d":"-1.95"},{"v":4.64728059690892E-3,"d":"0.00"},{"v":0.197051242774567,"d":"0.20"},"down","yes"]
["MSTRG.9016","IL1R2","ENST00000332549;ENST00000464994;ENST00000493749;ENST00000482658;ENST00000457817;ENST00000393414;ENST00000474085;ENST00000485335;ENST00000441002","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005886(plasma membrane);GO:0005576(extracellular region);GO:0019221(cytokine-mediated signaling pathway);GO:0005515(protein binding);GO:0004908(interleukin-1 receptor activity);GO:0004910(interleukin-1, Type II, blocking receptor activity);GO:0006955(immune response);GO:0019966(interleukin-1 binding);GO:0010955(negative regulation of protein processing);GO:0050712(negative regulation of interleukin-1 alpha secretion);GO:1900016(negative regulation of cytokine production involved in inflammatory response);GO:2000660(negative regulation of interleukin-1-mediated signaling pathway);GO:0005737(cytoplasm);GO:0005737(cytoplasm)","04060(Cytokine-cytokine receptor interaction);04640(Hematopoietic cell lineage);05202(Transcriptional misregulation in cancers);05215(Prostate cancer);05418(Fluid shear stress and atherosclerosis);05166(HTLV-I infection);05146(Amoebiasis);05146(Amoebiasis)","K04387","NA","interleukin 1 receptor type 2 [Source:HGNC Symbol;Acc:HGNC:5994]",{"v":4.15422502863651,"d":"4.15"},{"v":15.98680023137,"d":"15.99"},{"v":0.259853439619825,"d":"0.26"},{"v":-1.94422993913488,"d":"-1.94"},{"v":0.00470872303865757,"d":"0.00"},{"v":0.1989559397597,"d":"0.20"},"down","yes"]
["MSTRG.11655","CXCL8","ENST00000307407;ENST00000483500;ENST00000401931","GO:0005622(intracellular);GO:0071222(cellular response to lipopolysaccharide);GO:0005576(extracellular region);GO:0005515(protein binding);GO:0006955(immune response);GO:0006935(chemotaxis);GO:0005125(cytokine activity);GO:0005615(extracellular space);GO:0008009(chemokine activity);GO:0006952(defense response);GO:0005153(interleukin-8 receptor binding);GO:0006954(inflammatory response);GO:0030593(neutrophil chemotaxis);GO:0042119(neutrophil activation);GO:0070098(chemokine-mediated signaling pathway);GO:0007050(cell cycle arrest);GO:0071347(cellular response to interleukin-1);GO:0071356(cellular response to tumor necrosis factor);GO:0007186(G-protein coupled receptor signaling pathway);GO:0007165(signal transduction);GO:0006928(movement of cell or subcellular component);GO:0034976(response to endoplasmic reticulum stress);GO:0001525(angiogenesis);GO:0030155(regulation of cell adhesion);GO:0035556(intracellular signal transduction);GO:0090023(positive regulation of neutrophil chemotaxis);GO:0008285(negative regulation of cell proliferation);GO:0044344(cellular response to fibroblast growth factor stimulus);GO:0019722(calcium-mediated signaling);GO:0050930(induction of positive chemotaxis);GO:0045744(negative regulation of G-protein coupled receptor protein signaling pathway);GO:0031623(receptor internalization);GO:0048566(embryonic digestive tract development);GO:0045766(positive regulation of angiogenesis);GO:0036499(PERK-mediated unfolded protein response);GO:0002237(response to molecule of bacterial origin);GO:0045091(regulation of single stranded viral RNA replication via double stranded DNA intermediate);GO:2000535(regulation of entry of bacterium into host cell);GO:2000535(regulation of entry of bacterium into host cell)","04064(NF-kappa B signaling pathway);04072(Phospholipase D signaling pathway);04060(Cytokine-cytokine receptor interaction);04218(Cellular senescence);04620(Toll-like receptor signaling pathway);04621(NOD-like receptor signaling pathway);04622(RIG-I-like receptor signaling pathway);04657(IL-17 signaling pathway);04062(Chemokine signaling pathway);05200(Pathways in cancer);05202(Transcriptional misregulation in cancers);05219(Bladder cancer);05323(Rheumatoid arthritis);04932(Non-alcoholic fatty liver disease (NAFLD));04933(AGE-RAGE signaling pathway in diabetic complications);05120(Epithelial cell signaling in Helicobacter pylori infection);05132(Salmonella infection);05131(Shigellosis);05133(Pertussis);05134(Legionellosis);05164(Influenza A);05161(Hepatitis B);05160(Hepatitis C);05167(Kaposi's sarcoma-associated herpesvirus infection);05146(Amoebiasis);05144(Malaria);05142(Chagas disease (American trypanosomiasis));05142(Chagas disease (American trypanosomiasis))","K10030","NA","C-X-C motif chemokine ligand 8 [Source:HGNC Symbol;Acc:HGNC:6025]",{"v":4.11415951187335,"d":"4.11"},{"v":15.8111211671064,"d":"15.81"},{"v":0.260206690492796,"d":"0.26"},{"v":-1.94227003745623,"d":"-1.94"},{"v":0.00475388911972358,"d":"0.00"},{"v":0.200162002726263,"d":"0.20"},"down","yes"]
["ENSG00000182903","ZNF721","ENST00000505900;ENST00000511833;ENST00000515578;ENST00000338977;ENST00000506646","GO:0003676(nucleic acid binding);GO:0006355(regulation of transcription, DNA-templated);GO:0005622(intracellular);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0003677(DNA binding)","NA","NA","NA","zinc finger protein 721 [Source:HGNC Symbol;Acc:HGNC:29425]",{"v":1.03015917464789,"d":"1.03"},{"v":0.271406702347418,"d":"0.27"},{"v":3.79562908998916,"d":"3.80"},{"v":1.92433901865566,"d":"1.92"},{"v":4.82256911135599E-3,"d":"0.00"},{"v":0.202346262156616,"d":"0.20"},"up","yes"]
["MSTRG.637","WLS","MSTRG.637.2;ENST00000262348;ENST00000491076;ENST00000527864;ENST00000491811;ENST00000370971;ENST00000498615;ENST00000497187","GO:0090263(positive regulation of canonical Wnt signaling pathway);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005783(endoplasmic reticulum);GO:0005794(Golgi apparatus);GO:0005789(endoplasmic reticulum membrane);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0004871(signal transducer activity);GO:0000139(Golgi membrane);GO:0007275(multicellular organism development);GO:0016055(Wnt signaling pathway);GO:0030659(cytoplasmic vesicle membrane);GO:0031410(cytoplasmic vesicle);GO:0005768(endosome);GO:0017147(Wnt-protein binding);GO:0031901(early endosome membrane);GO:0043123(positive regulation of I-kappaB kinase/NF-kappaB signaling);GO:0030666(endocytic vesicle membrane);GO:0070062(extracellular exosome);GO:0005769(early endosome);GO:0005802(trans-Golgi network);GO:0006886(intracellular protein transport);GO:0009948(anterior/posterior axis specification);GO:0030177(positive regulation of Wnt signaling pathway);GO:0031852(mu-type opioid receptor binding);GO:0001707(mesoderm formation);GO:0030901(midbrain development);GO:0030902(hindbrain development);GO:0031017(exocrine pancreas development);GO:0061355(Wnt protein secretion);GO:0061357(positive regulation of Wnt protein secretion);GO:0032590(dendrite membrane);GO:0032839(dendrite cytoplasm);GO:0032839(dendrite cytoplasm)","NA","NA","NA","wntless Wnt ligand secretion mediator [Source:HGNC Symbol;Acc:HGNC:30238]",{"v":2.72775525934213,"d":"2.73"},{"v":10.442992053032,"d":"10.44"},{"v":0.26120437950062,"d":"0.26"},{"v":-1.93674900875777,"d":"-1.94"},{"v":0.00484506608990026,"d":"0.00"},{"v":0.202584325883955,"d":"0.20"},"down","yes"]
["MSTRG.1759","PRF1","ENST00000441259;ENST00000373209;ENST00000638674;ENST00000639390","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0046872(metal ion binding);GO:0005829(cytosol);GO:0055085(transmembrane transport);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0005509(calcium ion binding);GO:0019835(cytolysis);GO:0051607(defense response to virus);GO:0005768(endosome);GO:0006915(apoptotic process);GO:0051260(protein homooligomerization);GO:0006968(cellular defense response);GO:0031904(endosome lumen);GO:0022829(wide pore channel activity);GO:0001771(immunological synapse formation);GO:0002357(defense response to tumor cell);GO:0002418(immune response to tumor cell);GO:0051712(positive regulation of killing of cells of other organism);GO:0044194(cytolytic granule);GO:0031410(cytoplasmic vesicle);GO:0031410(cytoplasmic vesicle)","04210(Apoptosis);04650(Natural killer cell mediated cytotoxicity);05320(Autoimmune thyroid disease);05330(Allograft rejection);05332(Graft-versus-host disease);05416(Viral myocarditis);04940(Type I diabetes mellitus);04940(Type I diabetes mellitus)","K07818","NA","perforin 1 [Source:HGNC Symbol;Acc:HGNC:9360]",{"v":70.6399042020521,"d":"70.64"},{"v":19.2828115331492,"d":"19.28"},{"v":3.66336123135439,"d":"3.66"},{"v":1.8731679672186,"d":"1.87"},{"v":0.00494058800120076,"d":"0.00"},{"v":0.205863531870102,"d":"0.21"},"up","yes"]
["MSTRG.2579","RAB1B","ENST00000311481;ENST00000527397","GO:0006810(transport);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0015031(protein transport);GO:0005525(GTP binding);GO:0000166(nucleotide binding);GO:0003924(GTPase activity);GO:0005515(protein binding);GO:0006914(autophagy);GO:0034045(pre-autophagosomal structure membrane);GO:0005789(endoplasmic reticulum membrane);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0006890(retrograde vesicle-mediated transport, Golgi to ER);GO:0043687(post-translational protein modification);GO:0006888(ER to Golgi vesicle-mediated transport);GO:0000139(Golgi membrane);GO:0030133(transport vesicle);GO:0048208(COPII vesicle coating);GO:0005794(Golgi apparatus);GO:0033116(endoplasmic reticulum-Golgi intermediate compartment membrane);GO:0019068(virion assembly);GO:1903020(positive regulation of glycoprotein metabolic process);GO:2000785(regulation of autophagosome assembly);GO:0005739(mitochondrion);GO:0005793(endoplasmic reticulum-Golgi intermediate compartment);GO:0005793(endoplasmic reticulum-Golgi intermediate compartment)","05134(Legionellosis);05134(Legionellosis)","K07875","NA","RAB1B, member RAS oncogene family [Source:HGNC Symbol;Acc:HGNC:18370]",{"v":34.4680104055805,"d":"34.47"},{"v":130.515244,"d":"130.52"},{"v":0.264091835935889,"d":"0.26"},{"v":-1.92088839178016,"d":"-1.92"},{"v":0.00504115089795531,"d":"0.01"},{"v":0.209329445217855,"d":"0.21"},"down","yes"]
["ENSG00000169902","TPST1","ENST00000304842;ENST00000490159;ENST00000480281;ENST00000442120","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016740(transferase activity);GO:0005794(Golgi apparatus);GO:0008476(protein-tyrosine sulfotransferase activity);GO:0006478(peptidyl-tyrosine sulfation);GO:0000139(Golgi membrane);GO:0006954(inflammatory response);GO:0050427(3'-phosphoadenosine 5'-phosphosulfate metabolic process);GO:0050427(3'-phosphoadenosine 5'-phosphosulfate metabolic process)","NA","NA","NA","tyrosylprotein sulfotransferase 1 [Source:HGNC Symbol;Acc:HGNC:12020]",{"v":0.934305977011494,"d":"0.93"},{"v":3.61178087913619,"d":"3.61"},{"v":0.258682906930652,"d":"0.26"},{"v":-1.95074336711558,"d":"-1.95"},{"v":0.0050684781704036,"d":"0.01"},{"v":0.209740942020619,"d":"0.21"},"down","yes"]
["MSTRG.6785","GSDMB","ENST00000477054;ENST00000464556;ENST00000418519;ENST00000309481;ENST00000523371;ENST00000479136;ENST00000519429;ENST00000524039;ENST00000468820;ENST00000394179;ENST00000486560;ENST00000360317;ENST00000520542;ENST00000394175","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0012501(programmed cell death);GO:0012501(programmed cell death)","NA","NA","NA","gasdermin B [Source:HGNC Symbol;Acc:HGNC:23690]",{"v":2.48952125012701,"d":"2.49"},{"v":0.672761467739204,"d":"0.67"},{"v":3.70045160061407,"d":"3.70"},{"v":1.88770134701432,"d":"1.89"},{"v":0.00512858371116252,"d":"0.01"},{"v":0.211501387156914,"d":"0.21"},"up","yes"]
["MSTRG.1316","CHI3L1","ENST00000255409;MSTRG.1316.1;ENST00000473185;ENST00000404436;ENST00000478742;ENST00000472064","GO:0005737(cytoplasm);GO:0005615(extracellular space);GO:0030246(carbohydrate binding);GO:0005975(carbohydrate metabolic process);GO:0005783(endoplasmic reticulum);GO:0005576(extracellular region);GO:0006915(apoptotic process);GO:0005578(proteinaceous extracellular matrix);GO:0048471(perinuclear region of cytoplasm);GO:0008061(chitin binding);GO:0006954(inflammatory response);GO:0007250(activation of NF-kappaB-inducing kinase activity);GO:0010800(positive regulation of peptidyl-threonine phosphorylation);GO:0045766(positive regulation of angiogenesis);GO:0051897(positive regulation of protein kinase B signaling);GO:0071347(cellular response to interleukin-1);GO:0071356(cellular response to tumor necrosis factor);GO:0072606(interleukin-8 secretion);GO:0070062(extracellular exosome);GO:0043312(neutrophil degranulation);GO:0070374(positive regulation of ERK1 and ERK2 cascade);GO:0070555(response to interleukin-1);GO:0051216(cartilage development);GO:0035580(specific granule lumen);GO:0034612(response to tumor necrosis factor);GO:0005201(extracellular matrix structural constituent);GO:0009612(response to mechanical stimulus);GO:0030324(lung development);GO:0070741(response to interleukin-6);GO:0070741(response to interleukin-6)","NA","NA","NA","chitinase 3 like 1 [Source:HGNC Symbol;Acc:HGNC:1932]",{"v":3.57030216989437,"d":"3.57"},{"v":13.5185973887911,"d":"13.52"},{"v":0.264103003234246,"d":"0.26"},{"v":-1.92082738775374,"d":"-1.92"},{"v":0.00517818916026258,"d":"0.01"},{"v":0.212818272586628,"d":"0.21"},"down","yes"]
["MSTRG.3580","DUSP6","ENST00000279488;ENST00000547291;MSTRG.3580.2;ENST00000548755;ENST00000308385;ENST00000547140","GO:0005737(cytoplasm);GO:0016787(hydrolase activity);GO:0008138(protein tyrosine/serine/threonine phosphatase activity);GO:0016791(phosphatase activity);GO:0006470(protein dephosphorylation);GO:0016311(dephosphorylation);GO:0035335(peptidyl-tyrosine dephosphorylation);GO:0004721(phosphoprotein phosphatase activity);GO:0017017(MAP kinase tyrosine/serine/threonine phosphatase activity);GO:0000188(inactivation of MAPK activity);GO:0004725(protein tyrosine phosphatase activity);GO:0001933(negative regulation of protein phosphorylation);GO:0010033(response to organic substance);GO:0010942(positive regulation of cell death);GO:0014070(response to organic cyclic compound);GO:0030154(cell differentiation);GO:0042493(response to drug);GO:0060420(regulation of heart growth);GO:0070373(negative regulation of ERK1 and ERK2 cascade);GO:0070848(response to growth factor);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0000165(MAPK cascade);GO:0043065(positive regulation of apoptotic process);GO:0000187(activation of MAPK activity);GO:0009953(dorsal/ventral pattern formation);GO:0040036(regulation of fibroblast growth factor receptor signaling pathway);GO:0042663(regulation of endodermal cell fate specification);GO:0051409(response to nitrosative stress);GO:0051409(response to nitrosative stress)","04010(MAPK signaling pathway);05202(Transcriptional misregulation in cancers);05221(Acute myeloid leukemia);05221(Acute myeloid leukemia)","K21946","EC:3.1.3.16;EC:3.1.3.48","dual specificity phosphatase 6 [Source:HGNC Symbol;Acc:HGNC:3072]",{"v":9.97373423347473,"d":"9.97"},{"v":37.5444274740191,"d":"37.54"},{"v":0.265651520199012,"d":"0.27"},{"v":-1.91239312618592,"d":"-1.91"},{"v":0.00524606969879923,"d":"0.01"},{"v":0.21487473235694,"d":"0.21"},"down","yes"]
["MSTRG.93","TPRG1L","ENST00000378344;ENST00000344579","GO:0016020(membrane);GO:0030054(cell junction);GO:0045202(synapse);GO:0031410(cytoplasmic vesicle);GO:0003674(molecular_function);GO:0008150(biological_process);GO:0070062(extracellular exosome);GO:0030672(synaptic vesicle membrane);GO:0008021(synaptic vesicle);GO:0042802(identical protein binding);GO:0042802(identical protein binding)","NA","NA","NA","tumor protein p63 regulated 1 like [Source:HGNC Symbol;Acc:HGNC:27007]",{"v":4.68402870256835,"d":"4.68"},{"v":17.646392915493,"d":"17.65"},{"v":0.265438309404066,"d":"0.27"},{"v":-1.91355149208153,"d":"-1.91"},{"v":0.00533818977276752,"d":"0.01"},{"v":0.217906716080225,"d":"0.22"},"down","yes"]
["ENSG00000145882","PCYOX1L","ENST00000274569;ENST00000503240;ENST00000507621;ENST00000510990;ENST00000514349;ENST00000511945","GO:0016020(membrane);GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0005576(extracellular region);GO:0001735(prenylcysteine oxidase activity);GO:0016670(oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor);GO:0030328(prenylcysteine catabolic process);GO:0002576(platelet degranulation);GO:0031093(platelet alpha granule lumen);GO:0005774(vacuolar membrane);GO:0030327(prenylated protein catabolic process);GO:0030327(prenylated protein catabolic process)","NA","NA","NA","prenylcysteine oxidase 1 like [Source:HGNC Symbol;Acc:HGNC:28477]",{"v":2.45480305832921,"d":"2.45"},{"v":0.668292237765695,"d":"0.67"},{"v":3.6732478990574,"d":"3.67"},{"v":1.8770562635273,"d":"1.88"},{"v":0.00549415477866027,"d":"0.01"},{"v":0.22282094606576,"d":"0.22"},"up","yes"]
["ENSG00000172667","ZMAT3","ENST00000311417;ENST00000414084;ENST00000432729","GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0006810(transport);GO:0005634(nucleus);GO:0015031(protein transport);GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0005654(nucleoplasm);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0006974(cellular response to DNA damage stimulus);GO:0006915(apoptotic process);GO:0005730(nucleolus);GO:0040008(regulation of growth);GO:0002039(p53 binding);GO:0072332(intrinsic apoptotic signaling pathway by p53 class mediator);GO:0043065(positive regulation of apoptotic process);GO:0043065(positive regulation of apoptotic process)","04115(p53 signaling pathway);04115(p53 signaling pathway)","K10137","NA","zinc finger matrin-type 3 [Source:HGNC Symbol;Acc:HGNC:29983]",{"v":1.56307960159652,"d":"1.56"},{"v":0.427554942981547,"d":"0.43"},{"v":3.65585669691107,"d":"3.66"},{"v":1.87020952042124,"d":"1.87"},{"v":0.00551184454873776,"d":"0.01"},{"v":0.22282094606576,"d":"0.22"},"up","yes"]
["MSTRG.3130","CLEC2B","ENST00000228438;ENST00000538152;ENST00000540743;ENST00000539028","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0030246(carbohydrate binding);GO:0050776(regulation of immune response);GO:0005886(plasma membrane);GO:0005887(integral component of plasma membrane);GO:0005887(integral component of plasma membrane)","05167(Kaposi's sarcoma-associated herpesvirus infection);05167(Kaposi's sarcoma-associated herpesvirus infection)","K10071","NA","C-type lectin domain family 2 member B [Source:HGNC Symbol;Acc:HGNC:2053]",{"v":3.17194589537528,"d":"3.17"},{"v":11.9301207187263,"d":"11.93"},{"v":0.265877099667264,"d":"0.27"},{"v":-1.91116857349939,"d":"-1.91"},{"v":0.00553832458216775,"d":"0.01"},{"v":0.22282094606576,"d":"0.22"},"down","yes"]
["MSTRG.1942","WBP1L","ENST00000448841;ENST00000369889","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005515(protein binding);GO:0005515(protein binding)","NA","NA","NA","WW domain binding protein 1 like [Source:HGNC Symbol;Acc:HGNC:23510]",{"v":9.9417287187573,"d":"9.94"},{"v":2.75667815954216,"d":"2.76"},{"v":3.60641618041058,"d":"3.61"},{"v":1.85056589337836,"d":"1.85"},{"v":0.0055460146439068,"d":"0.01"},{"v":0.22282094606576,"d":"0.22"},"up","yes"]
["ENSG00000004660","CAMKK1","ENST00000348335;ENST00000381769;ENST00000573483;ENST00000158166","GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005515(protein binding);GO:0005516(calmodulin binding);GO:0035556(intracellular signal transduction);GO:0005829(cytosol);GO:0018105(peptidyl-serine phosphorylation);GO:0018107(peptidyl-threonine phosphorylation);GO:0045860(positive regulation of protein kinase activity);GO:0004683(calmodulin-dependent protein kinase activity);GO:0004683(calmodulin-dependent protein kinase activity)","05034(Alcoholism);05034(Alcoholism)","K00908","EC:2.7.11.17","calcium/calmodulin dependent protein kinase kinase 1 [Source:HGNC Symbol;Acc:HGNC:1469]",{"v":0.357984583378233,"d":"0.36"},{"v":1.3640984454472,"d":"1.36"},{"v":0.262433099731943,"d":"0.26"},{"v":-1.92997840157939,"d":"-1.93"},{"v":5.56024754750212E-3,"d":"0.01"},{"v":0.22282094606576,"d":"0.22"},"down","yes"]
["MSTRG.15105","MAMDC4;PHPT1","ENST00000445819;ENST00000497413;ENST00000485732;ENST00000463215;ENST00000371661;ENST00000462205;ENST00000247665;ENST00000479475;ENST00000492540;ENST00000481327","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0015031(protein transport);GO:0005737(cytoplasm);GO:0016787(hydrolase activity);GO:0005829(cytosol);GO:0004721(phosphoprotein phosphatase activity);GO:0070062(extracellular exosome);GO:0044325(ion channel binding);GO:2000147(positive regulation of cell motility);GO:2000984(negative regulation of ATP citrate synthase activity);GO:0050860(negative regulation of T cell receptor signaling pathway);GO:0006470(protein dephosphorylation);GO:0019855(calcium channel inhibitor activity);GO:0008969(phosphohistidine phosphatase activity);GO:0035971(peptidyl-histidine dephosphorylation);GO:0051350(negative regulation of lyase activity);GO:2000249(regulation of actin cytoskeleton reorganization);GO:0035774(positive regulation of insulin secretion involved in cellular response to glucose stimulus);GO:0015031(protein transport)","NA","NA","NA","MAM domain containing 4 [Source:HGNC Symbol;Acc:HGNC:24083];phosphohistidine phosphatase 1 [Source:HGNC Symbol;Acc:HGNC:30033]",{"v":0.608882046794985,"d":"0.61"},{"v":0.161640618929896,"d":"0.16"},{"v":3.76688762283853,"d":"3.77"},{"v":1.91337299415818,"d":"1.91"},{"v":5.59843293189205E-3,"d":"0.01"},{"v":0.22282094606576,"d":"0.22"},"up","yes"]
["ENSG00000248049","UBA6-AS1","ENST00000506606;ENST00000502758;ENST00000500538;ENST00000498917;ENST00000514109","NA","NA","NA","NA","UBA6 antisense RNA 1 (head to head) [Source:HGNC Symbol;Acc:HGNC:49083]",{"v":0.784547356591928,"d":"0.78"},{"v":0.20524154044843,"d":"0.21"},{"v":3.82255636396891,"d":"3.82"},{"v":1.93453777442295,"d":"1.93"},{"v":0.00560542864804845,"d":"0.01"},{"v":0.22282094606576,"d":"0.22"},"up","yes"]
["MSTRG.8527","FAM49A","ENST00000381323;ENST00000406434;ENST00000469507;MSTRG.8527.2;ENST00000451689","GO:0005622(intracellular);GO:0005622(intracellular)","NA","NA","NA","family with sequence similarity 49 member A [Source:HGNC Symbol;Acc:HGNC:25373]",{"v":2.76431801371366,"d":"2.76"},{"v":10.3195263922106,"d":"10.32"},{"v":0.26787256591545,"d":"0.27"},{"v":-1.9003812593002,"d":"-1.90"},{"v":0.00560660576797253,"d":"0.01"},{"v":0.22282094606576,"d":"0.22"},"down","yes"]
["MSTRG.10239","DERL3","ENST00000406855;ENST00000464034;ENST00000404056;ENST00000464110;ENST00000464023;ENST00000318109;ENST00000290730;ENST00000476077","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0004252(serine-type endopeptidase activity);GO:0018279(protein N-linked glycosylation via asparagine);GO:0005515(protein binding);GO:0030433(ubiquitin-dependent ERAD pathway);GO:0030176(integral component of endoplasmic reticulum membrane);GO:0030968(endoplasmic reticulum unfolded protein response);GO:1904153(negative regulation of retrograde protein transport, ER to cytosol);GO:0005785(signal recognition particle receptor complex);GO:0048500(signal recognition particle);GO:0048500(signal recognition particle)","04141(Protein processing in endoplasmic reticulum);04141(Protein processing in endoplasmic reticulum)","K13989","NA","derlin 3 [Source:HGNC Symbol;Acc:HGNC:14236]",{"v":1.22358988066386,"d":"1.22"},{"v":0.330434574288725,"d":"0.33"},{"v":3.70297171020221,"d":"3.70"},{"v":1.88868352771454,"d":"1.89"},{"v":0.00565596921630255,"d":"0.01"},{"v":0.224043359548405,"d":"0.22"},"up","yes"]
["MSTRG.8671","AC079250.1","MSTRG.8671.1;ENST00000456046","NA","NA","NA","NA",null,{"v":24.1026333419773,"d":"24.10"},{"v":6.6456547828201,"d":"6.65"},{"v":3.6268259681929,"d":"3.63"},{"v":1.85870751981913,"d":"1.86"},{"v":0.00567834879131235,"d":"0.01"},{"v":0.224192380803224,"d":"0.22"},"up","yes"]
["ENSG00000164125","FAM198B","ENST00000296530;ENST00000585682;ENST00000592057;ENST00000589306","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005794(Golgi apparatus);GO:0000139(Golgi membrane);GO:0000139(Golgi membrane)","NA","NA","NA","family with sequence similarity 198 member B [Source:HGNC Symbol;Acc:HGNC:25312]",{"v":0.712673426395939,"d":"0.71"},{"v":2.66737473413706,"d":"2.67"},{"v":0.267181591425886,"d":"0.27"},{"v":-1.90410748405696,"d":"-1.90"},{"v":0.00580848286716729,"d":"0.01"},{"v":0.228580884596172,"d":"0.23"},"down","yes"]
["MSTRG.2227","ADM","ENST00000278175;ENST00000534464;ENST00000525063;ENST00000528655;ENST00000524948;ENST00000530439;ENST00000528544","GO:0005615(extracellular space);GO:0005737(cytoplasm);GO:0005576(extracellular region);GO:0005179(hormone activity);GO:0006171(cAMP biosynthetic process);GO:0005515(protein binding);GO:0007165(signal transduction);GO:0007267(cell-cell signaling);GO:0005102(receptor binding);GO:0009611(response to wounding);GO:0030816(positive regulation of cAMP metabolic process);GO:0030819(positive regulation of cAMP biosynthetic process);GO:0031623(receptor internalization);GO:0097647(amylin receptor signaling pathway);GO:0001570(vasculogenesis);GO:0008015(blood circulation);GO:0007565(female pregnancy);GO:0002031(G-protein coupled receptor internalization);GO:0003073(regulation of systemic arterial blood pressure);GO:0006701(progesterone biosynthetic process);GO:0010460(positive regulation of heart rate);GO:0035809(regulation of urine volume);GO:0045906(negative regulation of vasoconstriction);GO:0031700(adrenomedullin receptor binding);GO:0001666(response to hypoxia);GO:0001843(neural tube closure);GO:0002026(regulation of the force of heart contraction);GO:0007204(positive regulation of cytosolic calcium ion concentration);GO:0007507(heart development);GO:0007568(aging);GO:0008209(androgen metabolic process);GO:0008284(positive regulation of cell proliferation);GO:0008285(negative regulation of cell proliferation);GO:0009409(response to cold);GO:0010033(response to organic substance);GO:0019933(cAMP-mediated signaling);GO:0031100(animal organ regeneration);GO:0031102(neuron projection regeneration);GO:0032496(response to lipopolysaccharide);GO:0032868(response to insulin);GO:0042475(odontogenesis of dentin-containing tooth);GO:0042594(response to starvation);GO:0043065(positive regulation of apoptotic process);GO:0043116(negative regulation of vascular permeability);GO:0045766(positive regulation of angiogenesis);GO:0046879(hormone secretion);GO:0048589(developmental growth);GO:0051384(response to glucocorticoid);GO:0055074(calcium ion homeostasis);GO:0060670(branching involved in labyrinthine layer morphogenesis);GO:0060712(spongiotrophoblast layer development);GO:0097084(vascular smooth muscle cell development);GO:0097755(positive regulation of blood vessel diameter);GO:2001214(positive regulation of vasculogenesis);GO:2001214(positive regulation of vasculogenesis)","04270(Vascular smooth muscle contraction);04270(Vascular smooth muscle contraction)","K12333","NA","adrenomedullin [Source:HGNC Symbol;Acc:HGNC:259]",{"v":2.81658286460633,"d":"2.82"},{"v":10.5065538627667,"d":"10.51"},{"v":0.268078658463627,"d":"0.27"},{"v":-1.8992717228411,"d":"-1.90"},{"v":0.00583765979476811,"d":"0.01"},{"v":0.228980779311393,"d":"0.23"},"down","yes"]
["ENSG00000198040","ZNF84","ENST00000545299;ENST00000438628;ENST00000539354;ENST00000543124;ENST00000392319;ENST00000543758;ENST00000542874;ENST00000539686;ENST00000540031;ENST00000539098;ENST00000542358;ENST00000543310","GO:0003676(nucleic acid binding);GO:0046872(metal ion binding);GO:0006355(regulation of transcription, DNA-templated);GO:0005622(intracellular);GO:0005634(nucleus);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0008270(zinc ion binding);GO:0001570(vasculogenesis);GO:0001822(kidney development);GO:0006807(nitrogen compound metabolic process);GO:0009791(post-embryonic development);GO:0014909(smooth muscle cell migration);GO:0030097(hemopoiesis);GO:0035264(multicellular organism growth);GO:0048008(platelet-derived growth factor receptor signaling pathway);GO:0048705(skeletal system morphogenesis);GO:0048745(smooth muscle tissue development);GO:0060021(palate development);GO:0060325(face morphogenesis);GO:0060325(face morphogenesis)","NA","NA","NA","zinc finger protein 84 [Source:HGNC Symbol;Acc:HGNC:13159]",{"v":0.357728938865546,"d":"0.36"},{"v":0.0934661741596639,"d":"0.09"},{"v":3.8273625948833,"d":"3.83"},{"v":1.93635058484753,"d":"1.94"},{"v":0.00587872801586548,"d":"0.01"},{"v":0.229379203546018,"d":"0.23"},"up","yes"]
["MSTRG.15443","SH2D1A;TEX13D","ENST00000371139;ENST00000632372;ENST00000360027;ENST00000477673","GO:0005737(cytoplasm);GO:0009967(positive regulation of signal transduction);GO:0005515(protein binding);GO:0002376(immune system process);GO:0045087(innate immune response);GO:0002250(adaptive immune response);GO:0050776(regulation of immune response);GO:0005070(SH3/SH2 adaptor activity);GO:0005829(cytosol);GO:0007267(cell-cell signaling);GO:0006959(humoral immune response);GO:0006968(cellular defense response);GO:0045954(positive regulation of natural killer cell mediated cytotoxicity);GO:0045954(positive regulation of natural killer cell mediated cytotoxicity)","04650(Natural killer cell mediated cytotoxicity);05162(Measles);05162(Measles)","K07990","NA","SH2 domain containing 1A [Source:HGNC Symbol;Acc:HGNC:10820];TEX13 family member D [Source:HGNC Symbol;Acc:HGNC:52278]",{"v":2.99936881690532,"d":"3.00"},{"v":0.835450701237314,"d":"0.84"},{"v":3.5901206527964,"d":"3.59"},{"v":1.84403232935922,"d":"1.84"},{"v":5.88591379303434E-3,"d":"0.01"},{"v":0.229379203546018,"d":"0.23"},"up","yes"]
["ENSG00000137812","KNL1","ENST00000346991","GO:0005634(nucleus);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0051301(cell division);GO:0005694(chromosome);GO:0005515(protein binding);GO:0007049(cell cycle);GO:0016604(nuclear body);GO:0007059(chromosome segregation);GO:0000775(chromosome, centromeric region);GO:0000776(kinetochore);GO:0000777(condensed chromosome kinetochore);GO:0070062(extracellular exosome);GO:0001669(acrosomal vesicle);GO:0010923(negative regulation of phosphatase activity);GO:0034080(CENP-A containing nucleosome assembly);GO:0007062(sister chromatid cohesion);GO:0008608(attachment of spindle microtubules to kinetochore);GO:0071173(spindle assembly checkpoint);GO:0001675(acrosome assembly);GO:0034501(protein localization to kinetochore)","NA","NA","NA","kinetochore scaffold 1 [Source:HGNC Symbol;Acc:HGNC:24054]",{"v":0.330126539414634,"d":"0.33"},{"v":0.0869910184390244,"d":"0.09"},{"v":3.79494970099739,"d":"3.79"},{"v":1.92408076400635,"d":"1.92"},{"v":0.00592581380929798,"d":"0.01"},{"v":0.230189193198601,"d":"0.23"},"up","yes"]
["MSTRG.1329","PPP1R15B","ENST00000367188","GO:0050790(regulation of catalytic activity);GO:0005515(protein binding);GO:0006417(regulation of translation);GO:0001933(negative regulation of protein phosphorylation);GO:1903912(negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation);GO:1903898(negative regulation of PERK-mediated unfolded protein response);GO:0000164(protein phosphatase type 1 complex);GO:0070262(peptidyl-serine dephosphorylation);GO:0019888(protein phosphatase regulator activity);GO:0006979(response to oxidative stress);GO:0006983(ER overload response);GO:0034976(response to endoplasmic reticulum stress);GO:0042542(response to hydrogen peroxide)","NA","NA","NA","protein phosphatase 1 regulatory subunit 15B [Source:HGNC Symbol;Acc:HGNC:14951]",{"v":2.795988,"d":"2.80"},{"v":10.324797,"d":"10.32"},{"v":0.270803193515572,"d":"0.27"},{"v":-1.88468334252573,"d":"-1.88"},{"v":0.00599207772829257,"d":"0.01"},{"v":0.231656890423014,"d":"0.23"},"down","yes"]
["MSTRG.3288","LRRK2","ENST00000298910;ENST00000479187;ENST00000636518;ENST00000343742;ENST00000416796;ENST00000430804;ENST00000474202;MSTRG.3288.7;ENST00000481256","GO:0001934(positive regulation of protein phosphorylation);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0043231(intracellular membrane-bounded organelle);GO:0005525(GTP binding);GO:0007264(small GTPase mediated signal transduction);GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0005634(nucleus);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0005743(mitochondrial inner membrane);GO:0005794(Golgi apparatus);GO:0005783(endoplasmic reticulum);GO:0005739(mitochondrion);GO:0042803(protein homodimerization activity);GO:0043547(positive regulation of GTPase activity);GO:0042995(cell projection);GO:0005515(protein binding);GO:0005615(extracellular space);GO:0030054(cell junction);GO:0045202(synapse);GO:0005741(mitochondrial outer membrane);GO:0030154(cell differentiation);GO:0006914(autophagy);GO:0031410(cytoplasmic vesicle);GO:0005759(mitochondrial matrix);GO:0005096(GTPase activator activity);GO:0005764(lysosome);GO:0030425(dendrite);GO:0042802(identical protein binding);GO:0098794(postsynapse);GO:0005768(endosome);GO:0030424(axon);GO:0005829(cytosol);GO:0048812(neuron projection morphogenesis);GO:0043204(perikaryon);GO:0070062(extracellular exosome);GO:0010508(positive regulation of autophagy);GO:0044325(ion channel binding);GO:0031398(positive regulation of protein ubiquitination);GO:0000165(MAPK cascade);GO:0030276(clathrin binding);GO:0042391(regulation of membrane potential);GO:0046777(protein autophosphorylation);GO:0007005(mitochondrion organization);GO:0030672(synaptic vesicle membrane);GO:0007528(neuromuscular junction development);GO:0032436(positive regulation of proteasomal ubiquitin-dependent protein catabolic process);GO:0060070(canonical Wnt signaling pathway);GO:0030426(growth cone);GO:0043005(neuron projection);GO:0005886(plasma membrane);GO:0043195(terminal bouton);GO:0007030(Golgi organization);GO:1901214(regulation of neuron death);GO:0017048(Rho GTPase binding);GO:0018105(peptidyl-serine phosphorylation);GO:1903206(negative regulation of hydrogen peroxide-induced cell death);GO:0018107(peptidyl-threonine phosphorylation);GO:0034599(cellular response to oxidative stress);GO:1901215(negative regulation of neuron death);GO:1902236(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway);GO:0003779(actin binding);GO:0032092(positive regulation of protein binding);GO:0060828(regulation of canonical Wnt signaling pathway);GO:0071287(cellular response to manganese ion);GO:1902803(regulation of synaptic vesicle transport);GO:1903351(cellular response to dopamine);GO:0043025(neuronal cell body);GO:1990909(Wnt signalosome);GO:0032839(dendrite cytoplasm);GO:0039706(co-receptor binding);GO:0032091(negative regulation of protein binding);GO:0005622(intracellular);GO:1903215(negative regulation of protein targeting to mitochondrion);GO:0006979(response to oxidative stress);GO:0043068(positive regulation of programmed cell death);GO:0015631(tubulin binding);GO:0008340(determination of adult lifespan);GO:0010506(regulation of autophagy);GO:0008017(microtubule binding);GO:0090140(regulation of mitochondrial fission);GO:0009267(cellular response to starvation);GO:0003924(GTPase activity);GO:0046039(GTP metabolic process);GO:2000300(regulation of synaptic vesicle exocytosis);GO:0000149(SNARE binding);GO:0017075(syntaxin-1 binding);GO:0051966(regulation of synaptic transmission, glutamatergic);GO:0061001(regulation of dendritic spine morphogenesis);GO:0000187(activation of MAPK activity);GO:0016242(negative regulation of macroautophagy);GO:0060161(positive regulation of dopamine receptor signaling pathway);GO:0000186(activation of MAPKK activity);GO:0016234(inclusion body);GO:0010955(negative regulation of protein processing);GO:0035556(intracellular signal transduction);GO:0031966(mitochondrial membrane);GO:0006897(endocytosis);GO:0044753(amphisome);GO:0044754(autolysosome);GO:0090263(positive regulation of canonical Wnt signaling pathway);GO:0060079(excitatory postsynaptic potential);GO:1904713(beta-catenin destruction complex binding);GO:0004708(MAP kinase kinase activity);GO:0030159(receptor signaling complex scaffold activity);GO:0034211(GTP-dependent protein kinase activity);GO:0036479(peroxidase inhibitor activity);GO:0051018(protein kinase A binding);GO:0001933(negative regulation of protein phosphorylation);GO:0007040(lysosome organization);GO:0010738(regulation of protein kinase A signaling);GO:0014041(regulation of neuron maturation);GO:0019722(calcium-mediated signaling);GO:0021772(olfactory bulb development);GO:0022028(tangential migration from the subventricular zone to the olfactory bulb);GO:0034260(negative regulation of GTPase activity);GO:0034613(cellular protein localization);GO:0035564(regulation of kidney size);GO:0035640(exploration behavior);GO:0035641(locomotory exploration behavior);GO:0035751(regulation of lysosomal lumen pH);GO:0040012(regulation of locomotion);GO:0043406(positive regulation of MAP kinase activity);GO:0048312(intracellular distribution of mitochondria);GO:0051646(mitochondrion localization);GO:0051900(regulation of mitochondrial depolarization);GO:0060159(regulation of dopamine receptor signaling pathway);GO:0070585(protein localization to mitochondrion);GO:0070997(neuron death);GO:0071407(cellular response to organic cyclic compound);GO:0072593(reactive oxygen species metabolic process);GO:0090394(negative regulation of excitatory postsynaptic potential);GO:1902499(positive regulation of protein autoubiquitination);GO:1902692(regulation of neuroblast proliferation);GO:1902823(negative regulation of late endosome to lysosome transport);GO:1902902(negative regulation of autophagosome assembly);GO:1903125(negative regulation of thioredoxin peroxidase activity by peptidyl-threonine phosphorylation);GO:1903217(negative regulation of protein processing involved in protein targeting to mitochondrion);GO:1904887(Wnt signalosome assembly);GO:1905279(regulation of retrograde transport, endosome to Golgi);GO:1905289(regulation of CAMKK-AMPK signaling cascade);GO:2000172(regulation of branching morphogenesis of a nerve);GO:0005798(Golgi-associated vesicle);GO:0005802(trans-Golgi network);GO:0005902(microvillus);GO:0008021(synaptic vesicle);GO:0030529(intracellular ribonucleoprotein complex);GO:0032473(cytoplasmic side of mitochondrial outer membrane);GO:0045121(membrane raft);GO:0097487(multivesicular body, internal vesicle);GO:0099400(caveola neck);GO:0099400(caveola neck)","05012(Parkinson's disease);05012(Parkinson's disease)","K08844","EC:2.7.11.1","leucine rich repeat kinase 2 [Source:HGNC Symbol;Acc:HGNC:18618]",{"v":6.25212804295065,"d":"6.25"},{"v":23.008839921821,"d":"23.01"},{"v":0.271727217199738,"d":"0.27"},{"v":-1.87976901643641,"d":"-1.88"},{"v":0.00601672768441081,"d":"0.01"},{"v":0.231656890423014,"d":"0.23"},"down","yes"]
["MSTRG.10109","BCL2L13","ENST00000618481;ENST00000418951;ENST00000355028;ENST00000317582;ENST00000611738;ENST00000493680;ENST00000485631;ENST00000337612;ENST00000399781;ENST00000538149;ENST00000464649;ENST00000479296;ENST00000543133;ENST00000498133;ENST00000399777;ENST00000399782","GO:0005634(nucleus);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0042981(regulation of apoptotic process);GO:0005739(mitochondrion);GO:0005515(protein binding);GO:0006915(apoptotic process);GO:0031966(mitochondrial membrane);GO:0008656(cysteine-type endopeptidase activator activity involved in apoptotic process);GO:0006919(activation of cysteine-type endopeptidase activity involved in apoptotic process);GO:0006919(activation of cysteine-type endopeptidase activity involved in apoptotic process)","04137(Mitophagy - animal);05134(Legionellosis);05134(Legionellosis)","K15485","NA","BCL2 like 13 [Source:HGNC Symbol;Acc:HGNC:17164]",{"v":5.10596219420517,"d":"5.11"},{"v":1.43104736074132,"d":"1.43"},{"v":3.56798966566707,"d":"3.57"},{"v":1.83511143663926,"d":"1.84"},{"v":0.00602130930928444,"d":"0.01"},{"v":0.231656890423014,"d":"0.23"},"up","yes"]
["MSTRG.13889","NAPEPLD","ENST00000479761;ENST00000414118;ENST00000418294;ENST00000465647;ENST00000427257;ENST00000425379;ENST00000420631;ENST00000341533","GO:0016020(membrane);GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0005829(cytosol);GO:0016787(hydrolase activity);GO:0006629(lipid metabolic process);GO:0016042(lipid catabolic process);GO:0070062(extracellular exosome);GO:0001523(retinoid metabolic process);GO:0042622(photoreceptor outer segment membrane);GO:0009395(phospholipid catabolic process);GO:0070290(N-acylphosphatidylethanolamine-specific phospholipase D activity);GO:0102200(-);GO:0004620(phospholipase activity);GO:0006644(phospholipid metabolic process);GO:0007568(aging);GO:0035900(response to isolation stress);GO:1903999(negative regulation of eating behavior);GO:0043227(membrane-bounded organelle);GO:0043227(membrane-bounded organelle)","04723(Retrograde endocannabinoid signaling);04723(Retrograde endocannabinoid signaling)","K13985","EC:3.1.4.54","N-acyl phosphatidylethanolamine phospholipase D [Source:HGNC Symbol;Acc:HGNC:21683]",{"v":0.173937932151832,"d":"0.17"},{"v":0.674172429837323,"d":"0.67"},{"v":0.25800214374504,"d":"0.26"},{"v":-1.9545450418067,"d":"-1.95"},{"v":6.06494906986659E-3,"d":"0.01"},{"v":0.232592728341826,"d":"0.23"},"down","yes"]
["MSTRG.11588","RBM47","ENST00000295971;ENST00000381795;ENST00000514014;MSTRG.11588.1;ENST00000511598;ENST00000381793;ENST00000513473;ENST00000513044;ENST00000511902;ENST00000515809;ENST00000505220;ENST00000505414;ENST00000507180;ENST00000514782;ENST00000515053;ENST00000510871","GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0005634(nucleus);GO:0002244(hematopoietic progenitor cell differentiation);GO:0016554(cytidine to uridine editing);GO:0016554(cytidine to uridine editing)","NA","NA","NA","RNA binding motif protein 47 [Source:HGNC Symbol;Acc:HGNC:30358]",{"v":2.07711783351434,"d":"2.08"},{"v":7.62929012130756,"d":"7.63"},{"v":0.272255714553735,"d":"0.27"},{"v":-1.87696576395506,"d":"-1.88"},{"v":0.00614967461280041,"d":"0.01"},{"v":0.235093275197913,"d":"0.24"},"down","yes"]
["ENSG00000169891","REPS2","ENST00000303843;ENST00000357277;ENST00000469714;ENST00000470686","GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0005509(calcium ion binding);GO:0005515(protein binding);GO:0005829(cytosol);GO:0061024(membrane organization);GO:0006461(protein complex assembly);GO:0007173(epidermal growth factor receptor signaling pathway);GO:0007173(epidermal growth factor receptor signaling pathway)","NA","NA","NA","RALBP1 associated Eps domain containing 2 [Source:HGNC Symbol;Acc:HGNC:9963]",{"v":0.77000439925736,"d":"0.77"},{"v":2.8389252397666,"d":"2.84"},{"v":0.271230953345099,"d":"0.27"},{"v":-1.8824062641666,"d":"-1.88"},{"v":0.00620963465073445,"d":"0.01"},{"v":0.236022175863194,"d":"0.24"},"down","yes"]
["MSTRG.4740","IGHV2-5","ENST00000390597","GO:0016020(membrane);GO:0005886(plasma membrane);GO:0005576(extracellular region);GO:0006508(proteolysis);GO:0006955(immune response);GO:0002376(immune system process);GO:0003823(antigen binding);GO:0002250(adaptive immune response);GO:0004252(serine-type endopeptidase activity);GO:0006898(receptor-mediated endocytosis);GO:0006956(complement activation);GO:0006958(complement activation, classical pathway);GO:0030449(regulation of complement activation);GO:0038095(Fc-epsilon receptor signaling pathway);GO:0038096(Fc-gamma receptor signaling pathway involved in phagocytosis);GO:0050776(regulation of immune response);GO:0050900(leukocyte migration)","NA","NA","NA","immunoglobulin heavy variable 2-5 [Source:HGNC Symbol;Acc:HGNC:5576]",{"v":12.226793,"d":"12.23"},{"v":3.305115,"d":"3.31"},{"v":3.69935478795745,"d":"3.70"},{"v":1.88727366928629,"d":"1.89"},{"v":0.0062131730400791,"d":"0.01"},{"v":0.236022175863194,"d":"0.24"},"up","yes"]
["ENSG00000073464","CLCN4","ENST00000421085;ENST00000380833","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0055085(transmembrane transport);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0005216(ion channel activity);GO:1903959(regulation of anion transmembrane transport);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0006811(ion transport);GO:0015297(antiporter activity);GO:0006821(chloride transport);GO:1902476(chloride transmembrane transport);GO:0005247(voltage-gated chloride channel activity);GO:0005887(integral component of plasma membrane);GO:0005768(endosome);GO:0031902(late endosome membrane);GO:0034220(ion transmembrane transport);GO:0010008(endosome membrane);GO:0031901(early endosome membrane);GO:0005254(chloride channel activity);GO:0005254(chloride channel activity)","NA","NA","NA","chloride voltage-gated channel 4 [Source:HGNC Symbol;Acc:HGNC:2022]",{"v":0.375738204153778,"d":"0.38"},{"v":1.40036817587274,"d":"1.40"},{"v":0.26831386961476,"d":"0.27"},{"v":-1.89800646292308,"d":"-1.90"},{"v":0.00626848956994352,"d":"0.01"},{"v":0.237374689941069,"d":"0.24"},"down","yes"]
["ENSG00000131263","RLIM","ENST00000332687;ENST00000349225","GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0016740(transferase activity);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0016567(protein ubiquitination);GO:0006511(ubiquitin-dependent protein catabolic process);GO:0061630(ubiquitin protein ligase activity);GO:0043161(proteasome-mediated ubiquitin-dependent protein catabolic process);GO:0003714(transcription corepressor activity);GO:0000209(protein polyubiquitination);GO:0004842(ubiquitin-protein transferase activity);GO:0045892(negative regulation of transcription, DNA-templated);GO:0017053(transcriptional repressor complex);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0043433(negative regulation of sequence-specific DNA binding transcription factor activity);GO:0060816(random inactivation of X chromosome);GO:1900095(regulation of dosage compensation by inactivation of X chromosome);GO:1900095(regulation of dosage compensation by inactivation of X chromosome)","NA","NA","NA","ring finger protein, LIM domain interacting [Source:HGNC Symbol;Acc:HGNC:13429]",{"v":1.10071309464137,"d":"1.10"},{"v":4.04341403508772,"d":"4.04"},{"v":0.272223691437399,"d":"0.27"},{"v":-1.87713546584158,"d":"-1.88"},{"v":0.0063039759405001,"d":"0.01"},{"v":0.237970151333863,"d":"0.24"},"down","yes"]
["ENSG00000110104","CCDC86","ENST00000227520;ENST00000545580","GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005730(nucleolus);GO:0005515(protein binding);GO:0016032(viral process);GO:0016032(viral process)","NA","NA","NA","coiled-coil domain containing 86 [Source:HGNC Symbol;Acc:HGNC:28359]",{"v":4.0936726981409,"d":"4.09"},{"v":1.13323563209393,"d":"1.13"},{"v":3.61237555739122,"d":"3.61"},{"v":1.85294788911452,"d":"1.85"},{"v":0.00638367001300937,"d":"0.01"},{"v":0.240225482177059,"d":"0.24"},"up","yes"]
["ENSG00000231607","DLEU2","ENST00000621282;ENST00000235290;ENST00000458725;ENST00000425586;ENST00000443587;ENST00000449579","NA","NA","NA","NA","deleted in lymphocytic leukemia 2 (non-protein coding) [Source:HGNC Symbol;Acc:HGNC:13748]",{"v":0.170264766803841,"d":"0.17"},{"v":0.662070949441505,"d":"0.66"},{"v":0.257169970903374,"d":"0.26"},{"v":-1.95920590229163,"d":"-1.96"},{"v":0.00645690853933983,"d":"0.01"},{"v":0.242224587634674,"d":"0.24"},"down","yes"]
["ENSG00000101057","MYBL2","ENST00000217026;ENST00000396863","GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0006366(transcription from RNA polymerase II promoter);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0030154(cell differentiation);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0001077(transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0090307(mitotic spindle assembly);GO:0051726(regulation of cell cycle);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0001135(transcription factor activity, RNA polymerase II transcription factor recruiting);GO:0043525(positive regulation of neuron apoptotic process);GO:1990830(cellular response to leukemia inhibitory factor);GO:0031523(Myb complex);GO:0031523(Myb complex)","04218(Cellular senescence);05166(HTLV-I infection);05166(HTLV-I infection)","K21769","NA","MYB proto-oncogene like 2 [Source:HGNC Symbol;Acc:HGNC:7548]",{"v":2.74360078537991,"d":"2.74"},{"v":0.764803018725243,"d":"0.76"},{"v":3.58732996367206,"d":"3.59"},{"v":1.84291045091564,"d":"1.84"},{"v":0.00651940894700906,"d":"0.01"},{"v":0.243809697328829,"d":"0.24"},"up","yes"]
["MSTRG.3001",null,"MSTRG.3001.1","NA","NA","NA","NA",null,{"v":8.51654,"d":"8.52"},{"v":2.374211,"d":"2.37"},{"v":3.5871032524068,"d":"3.59"},{"v":1.84281927292057,"d":"1.84"},{"v":0.00654329367331702,"d":"0.01"},{"v":0.243945332551342,"d":"0.24"},"up","yes"]
["MSTRG.9789","MMP9","ENST00000372330","GO:1904707(positive regulation of vascular smooth muscle cell proliferation);GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0016787(hydrolase activity);GO:0005515(protein binding);GO:0008233(peptidase activity);GO:0006508(proteolysis);GO:0005576(extracellular region);GO:0005578(proteinaceous extracellular matrix);GO:0005615(extracellular space);GO:0004222(metalloendopeptidase activity);GO:0008237(metallopeptidase activity);GO:0031012(extracellular matrix);GO:0050900(leukocyte migration);GO:0001503(ossification);GO:0004252(serine-type endopeptidase activity);GO:0042802(identical protein binding);GO:0070062(extracellular exosome);GO:0030574(collagen catabolic process);GO:0043312(neutrophil degranulation);GO:1904813(ficolin-1-rich granule lumen);GO:1904724(tertiary granule lumen);GO:0048013(ephrin receptor signaling pathway);GO:0022617(extracellular matrix disassembly);GO:0034614(cellular response to reactive oxygen species);GO:0071276(cellular response to cadmium ion);GO:0005518(collagen binding);GO:0001934(positive regulation of protein phosphorylation);GO:0043066(negative regulation of apoptotic process);GO:0035987(endodermal cell differentiation);GO:0004175(endopeptidase activity);GO:0030225(macrophage differentiation);GO:0001501(skeletal system development);GO:0007566(embryo implantation);GO:0030198(extracellular matrix organization);GO:0030335(positive regulation of cell migration);GO:0043065(positive regulation of apoptotic process);GO:0043388(positive regulation of DNA binding);GO:0045742(positive regulation of epidermal growth factor receptor signaling pathway);GO:0051549(positive regulation of keratinocyte migration);GO:0090200(positive regulation of release of cytochrome c from mitochondria);GO:1900122(positive regulation of receptor binding);GO:2001243(negative regulation of intrinsic apoptotic signaling pathway);GO:2001258(negative regulation of cation channel activity);GO:2001268(negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway)","04668(TNF signaling pathway);04657(IL-17 signaling pathway);04670(Leukocyte transendothelial migration);04915(Estrogen signaling pathway);04926(Relaxin signaling pathway);05200(Pathways in cancer);05202(Transcriptional misregulation in cancers);05206(MicroRNAs in cancer);05205(Proteoglycans in cancer);05219(Bladder cancer);05215(Prostate cancer);05418(Fluid shear stress and atherosclerosis);05161(Hepatitis B);01522(Endocrine resistance)","K01403","EC:3.4.24.35","matrix metallopeptidase 9 [Source:HGNC Symbol;Acc:HGNC:7176]",{"v":8.36675,"d":"8.37"},{"v":30.375893,"d":"30.38"},{"v":0.275440461947901,"d":"0.28"},{"v":-1.86018758928591,"d":"-1.86"},{"v":0.00659099762330031,"d":"0.01"},{"v":0.24448172109441,"d":"0.24"},"down","yes"]
["MSTRG.14898","GNG10;DNAJC25;DNAJC25-GNG10","ENST00000374293;MSTRG.14898.5;ENST00000313525;ENST00000447096;ENST00000463589;ENST00000374294","GO:0016020(membrane);GO:0007186(G-protein coupled receptor signaling pathway);GO:0004871(signal transducer activity);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0007165(signal transduction);GO:0005834(heterotrimeric G-protein complex);GO:0070062(extracellular exosome);GO:0003924(GTPase activity);GO:0071377(cellular response to glucagon stimulus);GO:0016021(integral component of membrane);GO:0005834(heterotrimeric G-protein complex)","04014(Ras signaling pathway);04371(Apelin signaling pathway);04151(PI3K-Akt signaling pathway);04062(Chemokine signaling pathway);04926(Relaxin signaling pathway);04724(Glutamatergic synapse);04727(GABAergic synapse);04725(Cholinergic synapse);04728(Dopaminergic synapse);04726(Serotonergic synapse);04723(Retrograde endocannabinoid signaling);04713(Circadian entrainment);05200(Pathways in cancer);05032(Morphine addiction);05034(Alcoholism);05167(Kaposi's sarcoma-associated herpesvirus infection)","K04545","NA","G protein subunit gamma 10 [Source:HGNC Symbol;Acc:HGNC:4402];DnaJ heat shock protein family (Hsp40) member C25 [Source:HGNC Symbol;Acc:HGNC:34187];DNAJC25-GNG10 readthrough [Source:HGNC Symbol;Acc:HGNC:37501]",{"v":3.44223493745624,"d":"3.44"},{"v":12.5248076114352,"d":"12.52"},{"v":0.2748333582636,"d":"0.27"},{"v":-1.8633709710782,"d":"-1.86"},{"v":0.0065982859454977,"d":"0.01"},{"v":0.24448172109441,"d":"0.24"},"down","yes"]
["MSTRG.2830","POU2AF1","ENST00000393067;ENST00000525890;ENST00000525584;ENST00000526535;ENST00000525499;ENST00000529065;ENST00000530793","GO:0005634(nucleus);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0005515(protein binding);GO:0003713(transcription coactivator activity);GO:0006366(transcription from RNA polymerase II promoter);GO:0003712(transcription cofactor activity);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0006959(humoral immune response);GO:0000979(RNA polymerase II core promoter sequence-specific DNA binding);GO:0001105(RNA polymerase II transcription coactivator activity);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0090575(RNA polymerase II transcription factor complex);GO:0003677(DNA binding);GO:0003677(DNA binding)","NA","NA","NA","POU class 2 associating factor 1 [Source:HGNC Symbol;Acc:HGNC:9211]",{"v":4.24762642300432,"d":"4.25"},{"v":1.21080931944444,"d":"1.21"},{"v":3.5080886435143,"d":"3.51"},{"v":1.81068520272642,"d":"1.81"},{"v":0.00668123291654395,"d":"0.01"},{"v":0.246795726322154,"d":"0.25"},"up","yes"]
["MSTRG.195","PADI4","ENST00000375448;ENST00000468945;ENST00000487048;ENST00000375453;ENST00000467001;MSTRG.195.3","GO:0005737(cytoplasm);GO:0005509(calcium ion binding);GO:0004668(protein-arginine deiminase activity);GO:0018101(protein citrullination);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0016787(hydrolase activity);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0016569(covalent chromatin modification);GO:0006334(nucleosome assembly);GO:0005515(protein binding);GO:0002376(immune system process);GO:0045087(innate immune response);GO:0006325(chromatin organization);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0006338(chromatin remodeling);GO:0043234(protein complex);GO:0006464(cellular protein modification process);GO:0042803(protein homodimerization activity);GO:0019827(stem cell population maintenance);GO:0016990(arginine deiminase activity);GO:0034618(arginine binding);GO:0019546(arginine deiminase pathway);GO:0036413(histone H3-R26 citrullination);GO:0036414(histone citrullination);GO:0036414(histone citrullination)","NA","NA","NA","peptidyl arginine deiminase 4 [Source:HGNC Symbol;Acc:HGNC:18368]",{"v":5.20203596020613,"d":"5.20"},{"v":18.8486269885485,"d":"18.85"},{"v":0.275990180259105,"d":"0.28"},{"v":-1.85731115811406,"d":"-1.86"},{"v":0.00672749229493553,"d":"0.01"},{"v":0.247157478854406,"d":"0.25"},"down","yes"]
["ENSG00000283378","BX088645.1","ENST00000636699","GO:0016021(integral component of membrane)","NA","NA","NA",null,{"v":0.510203,"d":"0.51"},{"v":1.954944,"d":"1.95"},{"v":0.260980877201598,"d":"0.26"},{"v":-1.93798399451801,"d":"-1.94"},{"v":0.00674163480938217,"d":"0.01"},{"v":0.247157478854406,"d":"0.25"},"down","yes"]
["MSTRG.13107","AL354719.2","ENST00000429530","NA","NA","NA","NA",null,{"v":0.791535,"d":"0.79"},{"v":3.002211,"d":"3.00"},{"v":0.263650689441881,"d":"0.26"},{"v":-1.92330032554272,"d":"-1.92"},{"v":0.00680459993680427,"d":"0.01"},{"v":0.247157478854406,"d":"0.25"},"down","yes"]
["ENSG00000089692","LAG3","ENST00000538079;ENST00000441671;ENST00000541049;ENST00000203629","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005886(plasma membrane);GO:0019886(antigen processing and presentation of exogenous peptide antigen via MHC class II);GO:0003823(antigen binding);GO:0042289(MHC class II protein binding);GO:0004888(transmembrane signaling receptor activity);GO:0007166(cell surface receptor signaling pathway);GO:0045085(negative regulation of interleukin-2 biosynthetic process);GO:0045954(positive regulation of natural killer cell mediated cytotoxicity);GO:0050868(negative regulation of T cell activation);GO:0009897(external side of plasma membrane);GO:0009897(external side of plasma membrane)","NA","NA","NA","lymphocyte activating 3 [Source:HGNC Symbol;Acc:HGNC:6476]",{"v":5.02126353861257,"d":"5.02"},{"v":1.42962179090314,"d":"1.43"},{"v":3.51230204419343,"d":"3.51"},{"v":1.81241691632052,"d":"1.81"},{"v":6.82426583589427E-3,"d":"0.01"},{"v":0.247157478854406,"d":"0.25"},"up","yes"]
["MSTRG.3066","MLF2","ENST00000203630;ENST00000541346;ENST00000537126;ENST00000539187;ENST00000541305;ENST00000542154;ENST00000564181;ENST00000536249;ENST00000536207","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005515(protein binding);GO:0006952(defense response);GO:0006952(defense response)","NA","NA","NA","myeloid leukemia factor 2 [Source:HGNC Symbol;Acc:HGNC:7126]",{"v":7.21404886749537,"d":"7.21"},{"v":26.0496250010579,"d":"26.05"},{"v":0.276934845211875,"d":"0.28"},{"v":-1.85238150325701,"d":"-1.85"},{"v":0.00683692308727071,"d":"0.01"},{"v":0.247157478854406,"d":"0.25"},"down","yes"]
["MSTRG.13025","TREM1","MSTRG.13025.3;ENST00000244709;ENST00000589614;MSTRG.13025.1;MSTRG.13025.2;ENST00000334475;ENST00000589882;ENST00000589695;ENST00000591620;ENST00000586287","GO:0005622(intracellular);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005886(plasma membrane);GO:0005576(extracellular region);GO:0050776(regulation of immune response);GO:0050900(leukocyte migration);GO:0045087(innate immune response);GO:0004872(receptor activity);GO:0097110(scaffold protein binding);GO:0035556(intracellular signal transduction);GO:0006959(humoral immune response);GO:0002374(cytokine secretion involved in immune response);GO:0016477(cell migration);GO:0030593(neutrophil chemotaxis);GO:0042107(cytokine metabolic process);GO:0050755(chemokine metabolic process);GO:0070945(neutrophil mediated killing of gram-negative bacterium);GO:0072672(neutrophil extravasation);GO:0072672(neutrophil extravasation)","NA","NA","NA","triggering receptor expressed on myeloid cells 1 [Source:HGNC Symbol;Acc:HGNC:17760]",{"v":5.223021333096,"d":"5.22"},{"v":18.8414358100154,"d":"18.84"},{"v":0.277209305371496,"d":"0.28"},{"v":-1.85095240816265,"d":"-1.85"},{"v":0.00684890615138221,"d":"0.01"},{"v":0.247157478854406,"d":"0.25"},"down","yes"]
["ENSG00000116791","CRYZ","ENST00000417775;ENST00000370871;ENST00000340866;ENST00000441120;ENST00000370872;ENST00000492102","GO:0003723(RNA binding);GO:0005737(cytoplasm);GO:0008270(zinc ion binding);GO:0005829(cytosol);GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0070062(extracellular exosome);GO:0007601(visual perception);GO:0003730(mRNA 3'-UTR binding);GO:0051289(protein homotetramerization);GO:0070402(NADPH binding);GO:0003960(NADPH:quinone reductase activity);GO:0042178(xenobiotic catabolic process);GO:0042178(xenobiotic catabolic process)","NA","NA","NA","crystallin zeta [Source:HGNC Symbol;Acc:HGNC:2419]",{"v":1.01206748176255,"d":"1.01"},{"v":0.278521038922889,"d":"0.28"},{"v":3.63372004383033,"d":"3.63"},{"v":1.86144727291932,"d":"1.86"},{"v":6.8494403394703E-3,"d":"0.01"},{"v":0.247157478854406,"d":"0.25"},"up","yes"]
["MSTRG.13327","STX11","ENST00000367568","GO:0006810(transport);GO:0016020(membrane);GO:0006886(intracellular protein transport);GO:0015031(protein transport);GO:0016192(vesicle-mediated transport);GO:0005794(Golgi apparatus);GO:0005515(protein binding);GO:0016021(integral component of membrane);GO:0005886(plasma membrane);GO:0005484(SNAP receptor activity);GO:0000149(SNARE binding);GO:0031201(SNARE complex);GO:0048278(vesicle docking);GO:0031629(synaptic vesicle fusion to presynaptic active zone membrane);GO:0061025(membrane fusion);GO:0008021(synaptic vesicle)","04130(SNARE interactions in vesicular transport)","K08487","NA","syntaxin 11 [Source:HGNC Symbol;Acc:HGNC:11429]",{"v":11.363338,"d":"11.36"},{"v":40.999428,"d":"41.00"},{"v":0.277158452064258,"d":"0.28"},{"v":-1.85121709099597,"d":"-1.85"},{"v":0.00685522321353359,"d":"0.01"},{"v":0.247157478854406,"d":"0.25"},"down","yes"]
["ENSG00000204116","CHIC1","ENST00000373502;ENST00000373504","GO:0016020(membrane);GO:0005886(plasma membrane);GO:0031410(cytoplasmic vesicle);GO:0005622(intracellular);GO:0006810(transport);GO:0016021(integral component of membrane);GO:0016021(integral component of membrane)","NA","NA","NA","cysteine rich hydrophobic domain 1 [Source:HGNC Symbol;Acc:HGNC:1934]",{"v":0.462579087332469,"d":"0.46"},{"v":0.125640630350195,"d":"0.13"},{"v":3.68176350312104,"d":"3.68"},{"v":1.88039695861817,"d":"1.88"},{"v":0.00687869722004715,"d":"0.01"},{"v":0.247263498280023,"d":"0.25"},"up","yes"]
["MSTRG.12988","BRPF3","ENST00000357641;ENST00000449261;ENST00000454960;ENST00000532538;ENST00000441123;ENST00000527657;ENST00000441730","GO:0046872(metal ion binding);GO:0016569(covalent chromatin modification);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0005829(cytosol);GO:0002576(platelet degranulation);GO:0043966(histone H3 acetylation);GO:0070776(MOZ/MORF histone acetyltransferase complex);GO:0070776(MOZ/MORF histone acetyltransferase complex)","NA","NA","NA","bromodomain and PHD finger containing 3 [Source:HGNC Symbol;Acc:HGNC:14256]",{"v":2.1205737761984,"d":"2.12"},{"v":7.6579211066082,"d":"7.66"},{"v":0.276912460532991,"d":"0.28"},{"v":-1.85249812119448,"d":"-1.85"},{"v":0.00693489538487818,"d":"0.01"},{"v":0.24854169709733,"d":"0.25"},"down","yes"]
["MSTRG.13000","MTCH1","ENST00000373616;ENST00000373627;ENST00000460219;ENST00000471737;ENST00000492754;ENST00000418541","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005743(mitochondrial inner membrane);GO:0005739(mitochondrion);GO:0006915(apoptotic process);GO:0005515(protein binding);GO:0005622(intracellular);GO:0043065(positive regulation of apoptotic process);GO:0009966(regulation of signal transduction);GO:0006919(activation of cysteine-type endopeptidase activity involved in apoptotic process);GO:0045161(neuronal ion channel clustering);GO:0045161(neuronal ion channel clustering)","NA","NA","NA","mitochondrial carrier 1 [Source:HGNC Symbol;Acc:HGNC:17586]",{"v":7.27457320057581,"d":"7.27"},{"v":26.0739770927703,"d":"26.07"},{"v":0.278997453081021,"d":"0.28"},{"v":-1.84167614288362,"d":"-1.84"},{"v":7.18009869786308E-3,"d":"0.01"},{"v":0.256081397020121,"d":"0.26"},"down","yes"]
["MSTRG.8531","RHOB","ENST00000272233","GO:0010595(positive regulation of endothelial cell migration);GO:0030336(negative regulation of cell migration);GO:0030334(regulation of cell migration);GO:0061154(endothelial tube morphogenesis);GO:0006810(transport);GO:0005634(nucleus);GO:0016020(membrane);GO:0015031(protein transport);GO:0005525(GTP binding);GO:0007264(small GTPase mediated signal transduction);GO:0000166(nucleotide binding);GO:0003924(GTPase activity);GO:0007155(cell adhesion);GO:0005622(intracellular);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0006915(apoptotic process);GO:0007275(multicellular organism development);GO:0030154(cell differentiation);GO:0005925(focal adhesion);GO:0005768(endosome);GO:0031902(late endosome membrane);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0051056(regulation of small GTPase mediated signal transduction);GO:0008333(endosome to lysosome transport);GO:0010008(endosome membrane);GO:0032154(cleavage furrow);GO:0043065(positive regulation of apoptotic process);GO:0030168(platelet activation);GO:0045786(negative regulation of cell cycle);GO:0001525(angiogenesis);GO:0045766(positive regulation of angiogenesis);GO:0000910(cytokinesis);GO:0007266(Rho protein signal transduction);GO:0071479(cellular response to ionizing radiation);GO:0070301(cellular response to hydrogen peroxide);GO:0019003(GDP binding);GO:0006886(intracellular protein transport);GO:0005769(early endosome);GO:0005770(late endosome)","NA","NA","NA","ras homolog family member B [Source:HGNC Symbol;Acc:HGNC:668]",{"v":9.201874,"d":"9.20"},{"v":32.937786,"d":"32.94"},{"v":0.279371357868437,"d":"0.28"},{"v":-1.83974397671452,"d":"-1.84"},{"v":0.0071878020422522,"d":"0.01"},{"v":0.256081397020121,"d":"0.26"},"down","yes"]
["MSTRG.10859","ABHD5","ENST00000458276;ENST00000463153;ENST00000013894;ENST00000413300;ENST00000454293;ENST00000486764;ENST00000456453","GO:0006508(proteolysis);GO:0008233(peptidase activity);GO:0005737(cytoplasm);GO:0016740(transferase activity);GO:0016787(hydrolase activity);GO:0016746(transferase activity, transferring acyl groups);GO:0006629(lipid metabolic process);GO:0005829(cytosol);GO:0006631(fatty acid metabolic process);GO:0008654(phospholipid biosynthetic process);GO:0030154(cell differentiation);GO:0003841(1-acylglycerol-3-phosphate O-acyltransferase activity);GO:0010891(negative regulation of sequestering of triglyceride);GO:0010898(positive regulation of triglyceride catabolic process);GO:0050996(positive regulation of lipid catabolic process);GO:0051006(positive regulation of lipoprotein lipase activity);GO:0005811(lipid particle);GO:0006654(phosphatidic acid biosynthetic process);GO:0042171(lysophosphatidic acid acyltransferase activity);GO:0042171(lysophosphatidic acid acyltransferase activity)","04923(Regulation of lipolysis in adipocyte);04923(Regulation of lipolysis in adipocyte)","K13699","EC:2.3.1.51","abhydrolase domain containing 5 [Source:HGNC Symbol;Acc:HGNC:21396]",{"v":4.13800531588903,"d":"4.14"},{"v":14.8056178420555,"d":"14.81"},{"v":0.279488864296834,"d":"0.28"},{"v":-1.83913729211864,"d":"-1.84"},{"v":0.00728498510726277,"d":"0.01"},{"v":0.258778143544715,"d":"0.26"},"down","yes"]
["MSTRG.12459","NDST1","MSTRG.12459.1;ENST00000523767;ENST00000518299;ENST00000522491;ENST00000261797;ENST00000521752;MSTRG.12459.4","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016787(hydrolase activity);GO:0015016([heparan sulfate]-glucosamine N-sulfotransferase activity);GO:0008146(sulfotransferase activity);GO:0016740(transferase activity);GO:0005794(Golgi apparatus);GO:0003824(catalytic activity);GO:0008152(metabolic process);GO:0000139(Golgi membrane);GO:0006954(inflammatory response);GO:0005515(protein binding);GO:0006024(glycosaminoglycan biosynthetic process);GO:0015012(heparan sulfate proteoglycan biosynthetic process);GO:0030210(heparin biosynthetic process);GO:0042328(heparan sulfate N-acetylglucosaminyltransferase activity);GO:0015014(heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process);GO:0019213(deacetylase activity);GO:0050119(N-acetylglucosamine deacetylase activity);GO:0000165(MAPK cascade);GO:0000271(polysaccharide biosynthetic process);GO:0003279(cardiac septum development);GO:0006477(protein sulfation);GO:0007224(smoothened signaling pathway);GO:0007507(heart development);GO:0007585(respiratory gaseous exchange);GO:0008543(fibroblast growth factor receptor signaling pathway);GO:0009887(animal organ morphogenesis);GO:0030203(glycosaminoglycan metabolic process);GO:0030900(forebrain development);GO:0030901(midbrain development);GO:0035904(aorta development);GO:0048702(embryonic neurocranium morphogenesis);GO:0048703(embryonic viscerocranium morphogenesis);GO:0060976(coronary vasculature development);GO:0060976(coronary vasculature development)","00534(Glycosaminoglycan biosynthesis - heparan sulfate / heparin);00534(Glycosaminoglycan biosynthesis - heparan sulfate / heparin)","K02576","EC:3.1.1.-;EC:2.8.2.-","N-deacetylase and N-sulfotransferase 1 [Source:HGNC Symbol;Acc:HGNC:7680]",{"v":2.42188076578569,"d":"2.42"},{"v":8.64347884993918,"d":"8.64"},{"v":0.280197453806777,"d":"0.28"},{"v":-1.8354842490295,"d":"-1.84"},{"v":0.00734240994760785,"d":"0.01"},{"v":0.26005088408557,"d":"0.26"},"down","yes"]
["MSTRG.10534","NFAM1","ENST00000329021;ENST00000355469","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005886(plasma membrane);GO:0004888(transmembrane signaling receptor activity);GO:0007166(cell surface receptor signaling pathway);GO:0043312(neutrophil degranulation);GO:0001819(positive regulation of cytokine production);GO:0045577(regulation of B cell differentiation);GO:0050861(positive regulation of B cell receptor signaling pathway);GO:0035577(azurophil granule membrane);GO:0035556(intracellular signal transduction);GO:0006954(inflammatory response);GO:0007165(signal transduction);GO:0051091(positive regulation of sequence-specific DNA binding transcription factor activity);GO:0030183(B cell differentiation);GO:0050853(B cell receptor signaling pathway);GO:0009986(cell surface);GO:0045121(membrane raft);GO:0045121(membrane raft)","NA","NA","NA","NFAT activating protein with ITAM motif 1 [Source:HGNC Symbol;Acc:HGNC:29872]",{"v":17.2634458992608,"d":"17.26"},{"v":61.4221449455046,"d":"61.42"},{"v":0.281062244156035,"d":"0.28"},{"v":-1.83103842924186,"d":"-1.83"},{"v":0.00737753479447125,"d":"0.01"},{"v":0.260528662742002,"d":"0.26"},"down","yes"]
["ENSG00000203999","LINC01270","ENST00000371639;ENST00000457853","NA","NA","NA","NA","long intergenic non-protein coding RNA 1270 [Source:HGNC Symbol;Acc:HGNC:27658]",{"v":0.500547412408759,"d":"0.50"},{"v":1.84556873689449,"d":"1.85"},{"v":0.271215805947722,"d":"0.27"},{"v":-1.88248683640603,"d":"-1.88"},{"v":0.00747227191010157,"d":"0.01"},{"v":0.263102626729366,"d":"0.26"},"down","yes"]
["ENSG00000163376","KBTBD8","ENST00000484414;ENST00000417314;ENST00000460576;ENST00000460784","GO:0005737(cytoplasm);GO:0005794(Golgi apparatus);GO:0005856(cytoskeleton);GO:0005819(spindle);GO:0004842(ubiquitin-protein transferase activity);GO:0005515(protein binding);GO:0005829(cytosol);GO:0043687(post-translational protein modification);GO:0006417(regulation of translation);GO:0042787(protein ubiquitination involved in ubiquitin-dependent protein catabolic process);GO:0031463(Cul3-RING ubiquitin ligase complex);GO:0006513(protein monoubiquitination);GO:0014029(neural crest formation);GO:0014032(neural crest cell development);GO:0014032(neural crest cell development)","NA","NA","NA","kelch repeat and BTB domain containing 8 [Source:HGNC Symbol;Acc:HGNC:30691]",{"v":0.201371205447635,"d":"0.20"},{"v":0.769603871621622,"d":"0.77"},{"v":0.26165565542612,"d":"0.26"},{"v":-1.93425865318281,"d":"-1.93"},{"v":7.49484535846237E-3,"d":"0.01"},{"v":0.263128069407008,"d":"0.26"},"down","yes"]
["MSTRG.9106","PTPN18","ENST00000175756;ENST00000481492;ENST00000462321;ENST00000428843;ENST00000483617;ENST00000462996;ENST00000460992;ENST00000464576;ENST00000490137;ENST00000490812;ENST00000489215;ENST00000347849;ENST00000479295;ENST00000495400;ENST00000420717;ENST00000409022","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016787(hydrolase activity);GO:0004725(protein tyrosine phosphatase activity);GO:0016791(phosphatase activity);GO:0006470(protein dephosphorylation);GO:0016311(dephosphorylation);GO:0035335(peptidyl-tyrosine dephosphorylation);GO:0004721(phosphoprotein phosphatase activity);GO:0005515(protein binding);GO:0005829(cytosol);GO:0038128(ERBB2 signaling pathway);GO:1901185(negative regulation of ERBB signaling pathway);GO:0004726(non-membrane spanning protein tyrosine phosphatase activity);GO:0004726(non-membrane spanning protein tyrosine phosphatase activity)","NA","NA","NA","protein tyrosine phosphatase, non-receptor type 18 [Source:HGNC Symbol;Acc:HGNC:9649]",{"v":7.01361430290959,"d":"7.01"},{"v":2.03862845081399,"d":"2.04"},{"v":3.44035927689971,"d":"3.44"},{"v":1.78255923351345,"d":"1.78"},{"v":0.00754763985079892,"d":"0.01"},{"v":0.264211276405002,"d":"0.26"},"up","yes"]
["ENSG00000164048","ZNF589","ENST00000457782;ENST00000354698;ENST00000412564;ENST00000440261;ENST00000448461;ENST00000454212","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0005654(nucleoplasm);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0005622(intracellular);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0000977(RNA polymerase II regulatory region sequence-specific DNA binding);GO:0001227(transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding);GO:0001227(transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding)","NA","NA","NA","zinc finger protein 589 [Source:HGNC Symbol;Acc:HGNC:16747]",{"v":0.672914909074443,"d":"0.67"},{"v":2.42748568646984,"d":"2.43"},{"v":0.277206540423736,"d":"0.28"},{"v":-1.85096679799819,"d":"-1.85"},{"v":7.57980240435279E-3,"d":"0.01"},{"v":0.264408845528167,"d":"0.26"},"down","yes"]
["MSTRG.11109","GCSAM","ENST00000308910;ENST00000470085;ENST00000488580;ENST00000484193;ENST00000487901;ENST00000460387;ENST00000495418","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0003779(actin binding);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0019901(protein kinase binding);GO:0050855(regulation of B cell receptor signaling pathway);GO:2000401(regulation of lymphocyte migration);GO:0045159(myosin II binding);GO:2000402(negative regulation of lymphocyte migration);GO:2000402(negative regulation of lymphocyte migration)","NA","NA","NA","germinal center associated signaling and motility [Source:HGNC Symbol;Acc:HGNC:20253]",{"v":2.8558393121861,"d":"2.86"},{"v":0.821623520486387,"d":"0.82"},{"v":3.47584902449664,"d":"3.48"},{"v":1.79736541922357,"d":"1.80"},{"v":0.00759719818574537,"d":"0.01"},{"v":0.264408845528167,"d":"0.26"},"up","yes"]
["MSTRG.10402","HMOX1","ENST00000216117;ENST00000481190;ENST00000412893;ENST00000494998","GO:0046872(metal ion binding);GO:0055114(oxidation-reduction process);GO:0004392(heme oxygenase (decyclizing) activity);GO:0006788(heme oxidation);GO:0005615(extracellular space);GO:0005634(nucleus);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016491(oxidoreductase activity);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0042803(protein homodimerization activity);GO:0005515(protein binding);GO:0004871(signal transducer activity);GO:0006915(apoptotic process);GO:0048471(perinuclear region of cytoplasm);GO:0043231(intracellular membrane-bounded organelle);GO:0043123(positive regulation of I-kappaB kinase/NF-kappaB signaling);GO:0019899(enzyme binding);GO:0001525(angiogenesis);GO:0048661(positive regulation of smooth muscle cell proliferation);GO:0071456(cellular response to hypoxia);GO:1902042(negative regulation of extrinsic apoptotic signaling pathway via death domain receptors);GO:0051260(protein homooligomerization);GO:0020037(heme binding);GO:0034605(cellular response to heat);GO:0045765(regulation of angiogenesis);GO:0008219(cell death);GO:0035556(intracellular signal transduction);GO:0048662(negative regulation of smooth muscle cell proliferation);GO:0006979(response to oxidative stress);GO:0006879(cellular iron ion homeostasis);GO:0042542(response to hydrogen peroxide);GO:0034383(low-density lipoprotein particle clearance);GO:0045080(positive regulation of chemokine biosynthetic process);GO:0055072(iron ion homeostasis);GO:0004630(phospholipase D activity);GO:0001666(response to hypoxia);GO:0001935(endothelial cell proliferation);GO:0002246(wound healing involved in inflammatory response);GO:0002686(negative regulation of leukocyte migration);GO:0007264(small GTPase mediated signal transduction);GO:0007588(excretion);GO:0008217(regulation of blood pressure);GO:0008285(negative regulation of cell proliferation);GO:0008630(intrinsic apoptotic signaling pathway in response to DNA damage);GO:0010656(negative regulation of muscle cell apoptotic process);GO:0014806(smooth muscle hyperplasia);GO:0016239(positive regulation of macroautophagy);GO:0016242(negative regulation of macroautophagy);GO:0031670(cellular response to nutrient);GO:0032764(negative regulation of mast cell cytokine production);GO:0034101(erythrocyte homeostasis);GO:0034395(regulation of transcription from RNA polymerase II promoter in response to iron);GO:0035094(response to nicotine);GO:0042167(heme catabolic process);GO:0042168(heme metabolic process);GO:0043065(positive regulation of apoptotic process);GO:0043305(negative regulation of mast cell degranulation);GO:0043392(negative regulation of DNA binding);GO:0043433(negative regulation of sequence-specific DNA binding transcription factor activity);GO:0043524(negative regulation of neuron apoptotic process);GO:0043619(regulation of transcription from RNA polymerase II promoter in response to oxidative stress);GO:0043627(response to estrogen);GO:0045766(positive regulation of angiogenesis);GO:0051090(regulation of sequence-specific DNA binding transcription factor activity);GO:0071243(cellular response to arsenic-containing substance);GO:0071276(cellular response to cadmium ion);GO:0072719(cellular response to cisplatin);GO:0097421(liver regeneration);GO:0097755(positive regulation of blood vessel diameter);GO:1904036(negative regulation of epithelial cell apoptotic process);GO:1904706(negative regulation of vascular smooth muscle cell proliferation);GO:0005730(nucleolus);GO:0005829(cytosol);GO:0005901(caveola);GO:0005901(caveola)","00860(Porphyrin and chlorophyll metabolism);04066(HIF-1 signaling pathway);04216(Ferroptosis);04978(Mineral absorption);05200(Pathways in cancer);05206(MicroRNAs in cancer);05225(Hepatocellular carcinoma);05418(Fluid shear stress and atherosclerosis);05418(Fluid shear stress and atherosclerosis)","K00510","EC:1.14.14.18","heme oxygenase 1 [Source:HGNC Symbol;Acc:HGNC:5013]",{"v":9.60621721746362,"d":"9.61"},{"v":33.9596363738046,"d":"33.96"},{"v":0.282871615930304,"d":"0.28"},{"v":-1.82178067464318,"d":"-1.82"},{"v":0.00777843036723436,"d":"0.01"},{"v":0.269936191591459,"d":"0.27"},"down","yes"]
["MSTRG.5919","AC007728.2","ENST00000563315;ENST00000567728","NA","NA","NA","NA",null,{"v":0.863830564388384,"d":"0.86"},{"v":0.239424135523614,"d":"0.24"},{"v":3.60795106349329,"d":"3.61"},{"v":1.85117977070683,"d":"1.85"},{"v":0.0078110902191217,"d":"0.01"},{"v":0.27029065637547,"d":"0.27"},"up","yes"]
["ENSG00000253981","ALG1L13P","ENST00000523017;ENST00000519320;ENST00000522393;ENST00000518201","NA","NA","NA","NA","asparagine-linked glycosylation 1-like 13, pseudogene [Source:HGNC Symbol;Acc:HGNC:44382]",{"v":1.17076878852799,"d":"1.17"},{"v":4.25039058120249,"d":"4.25"},{"v":0.27544969483646,"d":"0.28"},{"v":-1.86013923030772,"d":"-1.86"},{"v":0.00785770912403517,"d":"0.01"},{"v":0.271124737167999,"d":"0.27"},"down","yes"]
["MSTRG.14962","ZBTB34","ENST00000319119;ENST00000373452","GO:0003676(nucleic acid binding);GO:0005654(nucleoplasm);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0003677(DNA binding)","NA","NA","NA","zinc finger and BTB domain containing 34 [Source:HGNC Symbol;Acc:HGNC:31446]",{"v":2.63760244868301,"d":"2.64"},{"v":9.30206116076294,"d":"9.30"},{"v":0.28355032321317,"d":"0.28"},{"v":-1.81832329408582,"d":"-1.82"},{"v":0.00789886968387589,"d":"0.01"},{"v":0.271766253523524,"d":"0.27"},"down","yes"]
["MSTRG.15176","MOSPD2","ENST00000380492;ENST00000460386;ENST00000482354;ENST00000461777;ENST00000497603","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005886(plasma membrane);GO:0043312(neutrophil degranulation);GO:0035579(specific granule membrane);GO:0035579(specific granule membrane)","NA","NA","NA","motile sperm domain containing 2 [Source:HGNC Symbol;Acc:HGNC:28381]",{"v":1.76489762164074,"d":"1.76"},{"v":6.23767647595474,"d":"6.24"},{"v":0.282941513309346,"d":"0.28"},{"v":-1.82142422974143,"d":"-1.82"},{"v":0.00797215537481673,"d":"0.01"},{"v":0.273506253628328,"d":"0.27"},"down","yes"]
["MSTRG.429","YRDC","ENST00000373044","GO:0016020(membrane);GO:0005739(mitochondrion);GO:0003725(double-stranded RNA binding);GO:0005737(cytoplasm);GO:0000049(tRNA binding);GO:0051051(negative regulation of transport);GO:0016779(nucleotidyltransferase activity);GO:0002949(tRNA threonylcarbamoyladenosine modification);GO:0006450(regulation of translational fidelity)","NA","NA","NA","yrdC N6-threonylcarbamoyltransferase domain containing [Source:HGNC Symbol;Acc:HGNC:28905]",{"v":0.362855,"d":"0.36"},{"v":1.382708,"d":"1.38"},{"v":0.262423447322211,"d":"0.26"},{"v":-1.93003146554033,"d":"-1.93"},{"v":0.0080161318280683,"d":"0.01"},{"v":0.273612933957654,"d":"0.27"},"down","yes"]
["ENSG00000005801","ZNF195","ENST00000528218;ENST00000330692;ENST00000429541;ENST00000526540;ENST00000526598;ENST00000526601;ENST00000529085;ENST00000528410;ENST00000620374;ENST00000427810;ENST00000399602;ENST00000528636;ENST00000438262;ENST00000532539;ENST00000529228;ENST00000528796;ENST00000525313;ENST00000354599;ENST00000005082;ENST00000526501","GO:0003676(nucleic acid binding);GO:0006355(regulation of transcription, DNA-templated);GO:0005622(intracellular);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0008270(zinc ion binding);GO:0008270(zinc ion binding)","NA","NA","NA","zinc finger protein 195 [Source:HGNC Symbol;Acc:HGNC:12986]",{"v":0.243210730600806,"d":"0.24"},{"v":0.884885432124715,"d":"0.88"},{"v":0.274849965624169,"d":"0.27"},{"v":-1.86328379595136,"d":"-1.86"},{"v":0.00803854629249843,"d":"0.01"},{"v":0.273612933957654,"d":"0.27"},"down","yes"]
["ENSG00000198482","ZNF808","ENST00000487863;ENST00000359798;ENST00000461321;ENST00000486474;ENST00000465448;ENST00000461779","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0005622(intracellular);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding)","NA","NA","NA","zinc finger protein 808 [Source:HGNC Symbol;Acc:HGNC:33230]",{"v":0.149903661741214,"d":"0.15"},{"v":0.557362378594249,"d":"0.56"},{"v":0.268951883905931,"d":"0.27"},{"v":-1.89458000039299,"d":"-1.89"},{"v":0.00804342954833165,"d":"0.01"},{"v":0.273612933957654,"d":"0.27"},"down","yes"]
["MSTRG.11889","TMEM154","ENST00000304385;MSTRG.11889.2;ENST00000613578;ENST00000504064;ENST00000510252","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016021(integral component of membrane)","NA","NA","NA","transmembrane protein 154 [Source:HGNC Symbol;Acc:HGNC:26489]",{"v":4.51006960063596,"d":"4.51"},{"v":15.8170191863183,"d":"15.82"},{"v":0.285140300299892,"d":"0.29"},{"v":-1.81025613791972,"d":"-1.81"},{"v":0.00808118841810406,"d":"0.01"},{"v":0.274123016706505,"d":"0.27"},"down","yes"]
["MSTRG.10249","IGLL5;IGLV2-8;IGLV1-40;IGLC3;IGLV2-14;IGLV3-1;IGLV2-11;IGLC2;IGLV2-23;IGLC1;IGLJ1;IGLV3-25;IGLJ3;IGLV4-3;IGLV3-21;IGLV3-27;MIR650","MSTRG.10249.3;ENST00000620395;MSTRG.10249.1;ENST00000390325;ENST00000531372;ENST00000390312;ENST00000390319;ENST00000390299;ENST00000390314;MSTRG.10249.30;ENST00000390323;MSTRG.10249.4;MSTRG.10249.9;MSTRG.10249.19;MSTRG.10249.22;ENST00000390321;MSTRG.10249.16;ENST00000390306;MSTRG.10249.28;MSTRG.10249.20;ENST00000390320;ENST00000390305;ENST00000532223;MSTRG.10249.31;ENST00000390324;ENST00000390318;MSTRG.10249.15;MSTRG.10249.14;ENST00000390304;MSTRG.10249.32;MSTRG.10249.11;MSTRG.10249.5;MSTRG.10249.17;MSTRG.10249.25;MSTRG.10249.12;MSTRG.10249.7;ENST00000526893;ENST00000385101;MSTRG.10249.26;MSTRG.10249.23","GO:0016020(membrane);GO:0005886(plasma membrane);GO:0005576(extracellular region);GO:0006508(proteolysis);GO:0006955(immune response);GO:0002376(immune system process);GO:0003823(antigen binding);GO:0002250(adaptive immune response);GO:0004252(serine-type endopeptidase activity);GO:0006898(receptor-mediated endocytosis);GO:0006956(complement activation);GO:0006958(complement activation, classical pathway);GO:0030449(regulation of complement activation);GO:0038095(Fc-epsilon receptor signaling pathway);GO:0038096(Fc-gamma receptor signaling pathway involved in phagocytosis);GO:0050776(regulation of immune response);GO:0050900(leukocyte migration);GO:0005615(extracellular space);GO:0070062(extracellular exosome);GO:0072562(blood microparticle);GO:0034987(immunoglobulin receptor binding);GO:0006910(phagocytosis, recognition);GO:0006911(phagocytosis, engulfment);GO:0042742(defense response to bacterium);GO:0045087(innate immune response);GO:0050853(B cell receptor signaling pathway);GO:0050871(positive regulation of B cell activation);GO:0009897(external side of plasma membrane);GO:0042571(immunoglobulin complex, circulating);GO:0002377(immunoglobulin production);GO:0070062(extracellular exosome)","NA","NA","NA","immunoglobulin lambda variable 2-8 [Source:HGNC Symbol;Acc:HGNC:5895];immunoglobulin lambda constant 3 (Kern-Oz+ marker) [Source:HGNC Symbol;Acc:HGNC:5857];immunoglobulin lambda like polypeptide 5 [Source:HGNC Symbol;Acc:HGNC:38476];immunoglobulin lambda variable 2-14 [Source:HGNC Symbol;Acc:HGNC:5888];immunoglobulin lambda variable 3-1 [Source:HGNC Symbol;Acc:HGNC:5896];immunoglobulin lambda variable 1-40 [Source:HGNC Symbol;Acc:HGNC:5877];immunoglobulin lambda variable 2-11 [Source:HGNC Symbol;Acc:HGNC:5887];immunoglobulin lambda constant 2 [Source:HGNC Symbol;Acc:HGNC:5856];immunoglobulin lambda constant 1 [Source:HGNC Symbol;Acc:HGNC:5855];immunoglobulin lambda variable 2-23 [Source:HGNC Symbol;Acc:HGNC:5890];immunoglobulin lambda joining 1 [Source:HGNC Symbol;Acc:HGNC:5863];immunoglobulin lambda variable 3-25 [Source:HGNC Symbol;Acc:HGNC:5908];immunoglobulin lambda joining 3 [Source:HGNC Symbol;Acc:HGNC:5865];immunoglobulin lambda variable 4-3 [Source:HGNC Symbol;Acc:HGNC:5919];immunoglobulin lambda variable 3-27 [Source:HGNC Symbol;Acc:HGNC:5910];microRNA 650 [Source:HGNC Symbol;Acc:HGNC:32906]",{"v":42.5309827400419,"d":"42.53"},{"v":12.585897831499,"d":"12.59"},{"v":3.37925695166527,"d":"3.38"},{"v":1.75670605420078,"d":"1.76"},{"v":0.0081092105747698,"d":"0.01"},{"v":0.274300881296005,"d":"0.27"},"up","yes"]
["MSTRG.11326","GPR160;AC008040.2","ENST00000355897;ENST00000473675;ENST00000461049;ENST00000478364;ENST00000482813;ENST00000492492;ENST00000485735;ENST00000491740;ENST00000482710;ENST00000476668","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005886(plasma membrane);GO:0004871(signal transducer activity);GO:0007165(signal transduction);GO:0004930(G-protein coupled receptor activity);GO:0007186(G-protein coupled receptor signaling pathway);GO:0043235(receptor complex);GO:0043235(receptor complex)","NA","NA","NA","G protein-coupled receptor 160 [Source:HGNC Symbol;Acc:HGNC:23693]",{"v":1.30160438971379,"d":"1.30"},{"v":4.61720564105875,"d":"4.62"},{"v":0.281903058018296,"d":"0.28"},{"v":-1.8267289668765,"d":"-1.83"},{"v":0.00814603237162704,"d":"0.01"},{"v":0.274774570921941,"d":"0.27"},"down","yes"]
["MSTRG.10676","CHCHD4","ENST00000420103;ENST00000295767;ENST00000396914","GO:0006810(transport);GO:0015031(protein transport);GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0005739(mitochondrion);GO:0005515(protein binding);GO:0005758(mitochondrial intermembrane space);GO:0051084('de novo' posttranslational protein folding);GO:0015035(protein disulfide oxidoreductase activity);GO:0022417(protein maturation by protein folding);GO:0045041(protein import into mitochondrial intermembrane space);GO:0045041(protein import into mitochondrial intermembrane space)","NA","NA","NA","coiled-coil-helix-coiled-coil-helix domain containing 4 [Source:HGNC Symbol;Acc:HGNC:26467]",{"v":1.55331935891648,"d":"1.55"},{"v":0.430432731376975,"d":"0.43"},{"v":3.6087389403388,"d":"3.61"},{"v":1.85149478105694,"d":"1.85"},{"v":0.00825113575054897,"d":"0.01"},{"v":0.277542393039415,"d":"0.28"},"up","yes"]
["MSTRG.11431","FAM43A","ENST00000329759","NA","NA","NA","NA","family with sequence similarity 43 member A [Source:HGNC Symbol;Acc:HGNC:26888]",{"v":4.684036,"d":"4.68"},{"v":1.375484,"d":"1.38"},{"v":3.40537294508697,"d":"3.41"},{"v":1.76781280603879,"d":"1.77"},{"v":0.00836639518165835,"d":"0.01"},{"v":0.280635461775849,"d":"0.28"},"up","yes"]
["MSTRG.2723","DGAT2","ENST00000228027;ENST00000605099;ENST00000603363;ENST00000604935;ENST00000604733;ENST00000603865;ENST00000605608;ENST00000603276;ENST00000376262","GO:0016747(transferase activity, transferring acyl groups other than amino-acyl groups);GO:0048471(perinuclear region of cytoplasm);GO:0097006(regulation of plasma lipoprotein particle levels);GO:0042632(cholesterol homeostasis);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016740(transferase activity);GO:0016746(transferase activity, transferring acyl groups);GO:0006629(lipid metabolic process);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0042572(retinol metabolic process);GO:0042803(protein homodimerization activity);GO:0005811(lipid particle);GO:0005739(mitochondrion);GO:0019915(lipid storage);GO:0004144(diacylglycerol O-acyltransferase activity);GO:0050252(retinol O-fatty-acyltransferase activity);GO:0019432(triglyceride biosynthetic process);GO:0035336(long-chain fatty-acyl-CoA metabolic process);GO:0036155(acylglycerol acyl-chain remodeling);GO:0046339(diacylglycerol metabolic process);GO:0030176(integral component of endoplasmic reticulum membrane);GO:0034383(low-density lipoprotein particle clearance);GO:0055089(fatty acid homeostasis);GO:0006071(glycerol metabolic process);GO:0035356(cellular triglyceride homeostasis);GO:0003846(2-acylglycerol O-acyltransferase activity);GO:0010867(positive regulation of triglyceride biosynthetic process);GO:0045722(positive regulation of gluconeogenesis);GO:0046322(negative regulation of fatty acid oxidation);GO:0050746(regulation of lipoprotein metabolic process);GO:0060613(fat pad development);GO:0071400(cellular response to oleic acid);GO:0090181(regulation of cholesterol metabolic process);GO:0043231(intracellular membrane-bounded organelle);GO:0043231(intracellular membrane-bounded organelle)","00561(Glycerolipid metabolism);04975(Fat digestion and absorption);04975(Fat digestion and absorption)","K11160","EC:2.3.1.20;EC:2.3.1.75","diacylglycerol O-acyltransferase 2 [Source:HGNC Symbol;Acc:HGNC:16940]",{"v":2.19788342403542,"d":"2.20"},{"v":7.66784645793801,"d":"7.67"},{"v":0.286636337346074,"d":"0.29"},{"v":-1.80270658094006,"d":"-1.80"},{"v":0.00847670030689279,"d":"0.01"},{"v":0.282876564113048,"d":"0.28"},"down","yes"]
["MSTRG.1261","RGS18","MSTRG.1261.2;ENST00000367460;ENST00000492967;ENST00000481707;ENST00000491030;MSTRG.1261.1","GO:0005737(cytoplasm);GO:0007186(G-protein coupled receptor signaling pathway);GO:0043547(positive regulation of GTPase activity);GO:0005096(GTPase activator activity);GO:0005886(plasma membrane);GO:0009968(negative regulation of signal transduction);GO:0008277(regulation of G-protein coupled receptor protein signaling pathway);GO:0008277(regulation of G-protein coupled receptor protein signaling pathway)","NA","NA","NA","regulator of G protein signaling 18 [Source:HGNC Symbol;Acc:HGNC:14261]",{"v":6.20792321543274,"d":"6.21"},{"v":21.6228278047967,"d":"21.62"},{"v":0.287100432537117,"d":"0.29"},{"v":-1.80037259081846,"d":"-1.80"},{"v":0.00848018930782348,"d":"0.01"},{"v":0.282876564113048,"d":"0.28"},"down","yes"]
["MSTRG.10003","IL10RB-AS1","ENST00000411998","NA","NA","NA","NA","IL10RB antisense RNA 1 (head to head) [Source:HGNC Symbol;Acc:HGNC:44303]",{"v":9.602706,"d":"9.60"},{"v":2.84234,"d":"2.84"},{"v":3.37845085387392,"d":"3.38"},{"v":1.75636186847241,"d":"1.76"},{"v":0.00852877640935515,"d":"0.01"},{"v":0.283319733880963,"d":"0.28"},"up","yes"]
["ENSG00000143190","POU2F1","ENST00000367865;ENST00000442313;ENST00000367862;ENST00000470928;ENST00000560232;ENST00000559038;ENST00000443275;ENST00000492850;ENST00000271411;ENST00000541643;ENST00000490100;ENST00000559648;ENST00000429375;ENST00000367866","GO:0005634(nucleus);GO:0043231(intracellular membrane-bounded organelle);GO:0005783(endoplasmic reticulum);GO:0005654(nucleoplasm);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0043565(sequence-specific DNA binding);GO:0005515(protein binding);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0045892(negative regulation of transcription, DNA-templated);GO:0042795(snRNA transcription from RNA polymerase II promoter);GO:0000979(RNA polymerase II core promoter sequence-specific DNA binding);GO:0000983(transcription factor activity, RNA polymerase II core promoter sequence-specific);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0090575(RNA polymerase II transcription factor complex);GO:0090575(RNA polymerase II transcription factor complex)","NA","NA","NA","POU class 2 homeobox 1 [Source:HGNC Symbol;Acc:HGNC:9212]",{"v":1.0775597324954,"d":"1.08"},{"v":0.319673675363423,"d":"0.32"},{"v":3.37081159801591,"d":"3.37"},{"v":1.75309599421506,"d":"1.75"},{"v":0.00854053009456813,"d":"0.01"},{"v":0.283319733880963,"d":"0.28"},"up","yes"]
["ENSG00000238005","AL391832.2","ENST00000423175;ENST00000418557;ENST00000458044;ENST00000423988;ENST00000451766","NA","NA","NA","NA",null,{"v":0.378926042016807,"d":"0.38"},{"v":1.42189263805522,"d":"1.42"},{"v":0.266494130341008,"d":"0.27"},{"v":-1.90782433759213,"d":"-1.91"},{"v":0.00878288856627902,"d":"0.01"},{"v":0.290559187129483,"d":"0.29"},"down","yes"]
["MSTRG.8072","FFAR2","MSTRG.8072.2;ENST00000601590","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0004930(G-protein coupled receptor activity);GO:0007186(G-protein coupled receptor signaling pathway);GO:0005886(plasma membrane);GO:0004871(signal transducer activity);GO:0007165(signal transduction);GO:0002376(immune system process);GO:0006954(inflammatory response);GO:0008289(lipid binding);GO:0005515(protein binding);GO:0045444(fat cell differentiation);GO:0005887(integral component of plasma membrane);GO:0002232(leukocyte chemotaxis involved in inflammatory response);GO:0002385(mucosal immune response);GO:0002673(regulation of acute inflammatory response);GO:0002720(positive regulation of cytokine production involved in immune response);GO:0002879(positive regulation of acute inflammatory response to non-antigenic stimulus);GO:0019915(lipid storage);GO:0032722(positive regulation of chemokine production);GO:0042593(glucose homeostasis);GO:0071398(cellular response to fatty acid);GO:0090276(regulation of peptide hormone secretion);GO:0042995(cell projection);GO:2000484(positive regulation of interleukin-8 secretion);GO:0002752(cell surface pattern recognition receptor signaling pathway)","04024(cAMP signaling pathway)","NA","NA","free fatty acid receptor 2 [Source:HGNC Symbol;Acc:HGNC:4501]",{"v":1.32051985389931,"d":"1.32"},{"v":4.59669790819349,"d":"4.60"},{"v":0.287275753219614,"d":"0.29"},{"v":-1.79949186388956,"d":"-1.80"},{"v":0.00903940012801202,"d":"0.01"},{"v":0.297411477863196,"d":"0.30"},"down","yes"]
["ENSG00000156381","ANKRD9","ENST00000286918;ENST00000560748;ENST00000559404;ENST00000559651","GO:0005829(cytosol);GO:0043687(post-translational protein modification);GO:0043687(post-translational protein modification)","NA","NA","NA","ankyrin repeat domain 9 [Source:HGNC Symbol;Acc:HGNC:20096]",{"v":0.756356898544699,"d":"0.76"},{"v":0.220539482467082,"d":"0.22"},{"v":3.42957592030077,"d":"3.43"},{"v":1.77803019286916,"d":"1.78"},{"v":0.00904603715678224,"d":"0.01"},{"v":0.297411477863196,"d":"0.30"},"up","yes"]
["MSTRG.12262","TMED7-TICAM2;TMED7;TICAM2","ENST00000282382;ENST00000456936;ENST00000427199;ENST00000508420;ENST00000514548;ENST00000333314","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0006810(transport);GO:0015031(protein transport);GO:0005794(Golgi apparatus);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0031410(cytoplasmic vesicle);GO:0030663(COPI-coated vesicle membrane);GO:0070062(extracellular exosome);GO:0006890(retrograde vesicle-mediated transport, Golgi to ER);GO:0006888(ER to Golgi vesicle-mediated transport);GO:0000139(Golgi membrane);GO:0030133(transport vesicle);GO:0030126(COPI vesicle coat);GO:0033116(endoplasmic reticulum-Golgi intermediate compartment membrane);GO:0005793(endoplasmic reticulum-Golgi intermediate compartment);GO:0012507(ER to Golgi transport vesicle membrane);GO:0030127(COPII vesicle coat);GO:0005737(cytoplasm);GO:0007165(signal transduction);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0004871(signal transducer activity);GO:0002376(immune system process);GO:0045087(innate immune response);GO:0006954(inflammatory response);GO:0005768(endosome);GO:0031902(late endosome membrane);GO:0071222(cellular response to lipopolysaccharide);GO:0010008(endosome membrane);GO:0031901(early endosome membrane);GO:0043312(neutrophil degranulation);GO:0043123(positive regulation of I-kappaB kinase/NF-kappaB signaling);GO:0002756(MyD88-independent toll-like receptor signaling pathway);GO:0007249(I-kappaB kinase/NF-kappaB signaling);GO:0034128(negative regulation of MyD88-independent toll-like receptor signaling pathway);GO:0034142(toll-like receptor 4 signaling pathway);GO:0035666(TRIF-dependent toll-like receptor signaling pathway);GO:0070266(necroptotic process);GO:0097190(apoptotic signaling pathway);GO:0030667(secretory granule membrane);GO:0034145(positive regulation of toll-like receptor 4 signaling pathway);GO:0035669(TRAM-dependent toll-like receptor 4 signaling pathway);GO:2000494(positive regulation of interleukin-18-mediated signaling pathway);GO:0006810(transport)","04064(NF-kappa B signaling pathway);04217(Necroptosis);04620(Toll-like receptor signaling pathway);05133(Pertussis);05161(Hepatitis B)","K05409","NA","TMED7-TICAM2 readthrough [Source:HGNC Symbol;Acc:HGNC:33945];transmembrane p24 trafficking protein 7 [Source:HGNC Symbol;Acc:HGNC:24253];toll like receptor adaptor molecule 2 [Source:HGNC Symbol;Acc:HGNC:21354]",{"v":1.31382076545079,"d":"1.31"},{"v":4.54566951135581,"d":"4.55"},{"v":0.289026899595022,"d":"0.29"},{"v":-1.79072432497674,"d":"-1.79"},{"v":0.00906410997972038,"d":"0.01"},{"v":0.297411477863196,"d":"0.30"},"down","yes"]
["MSTRG.2758","GAB2","ENST00000361507;ENST00000530915;ENST00000526030;ENST00000528329;ENST00000534823;ENST00000528886","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0048015(phosphatidylinositol-mediated signaling);GO:0038095(Fc-epsilon receptor signaling pathway);GO:0005829(cytosol);GO:0005547(phosphatidylinositol-3,4,5-trisphosphate binding);GO:0043325(phosphatidylinositol-3,4-bisphosphate binding);GO:0008284(positive regulation of cell proliferation);GO:0007411(axon guidance);GO:0030316(osteoclast differentiation);GO:0043306(positive regulation of mast cell degranulation);GO:0005068(transmembrane receptor protein tyrosine kinase adaptor activity);GO:0007169(transmembrane receptor protein tyrosine kinase signaling pathway);GO:0007169(transmembrane receptor protein tyrosine kinase signaling pathway)","04014(Ras signaling pathway);04072(Phospholipase D signaling pathway);04071(Sphingolipid signaling pathway);04664(Fc epsilon RI signaling pathway);04666(Fc gamma R-mediated phagocytosis);04380(Osteoclast differentiation);05220(Chronic myeloid leukemia);05220(Chronic myeloid leukemia)","K08091","NA","GRB2 associated binding protein 2 [Source:HGNC Symbol;Acc:HGNC:14458]",{"v":8.20540121518239,"d":"8.21"},{"v":28.1482151307045,"d":"28.15"},{"v":0.291506981067223,"d":"0.29"},{"v":-1.77839766109979,"d":"-1.78"},{"v":0.00919875128544009,"d":"0.01"},{"v":0.300090542742956,"d":"0.30"},"down","yes"]
["MSTRG.8530","LAPTM4A","ENST00000175091;ENST00000483117","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005794(Golgi apparatus);GO:0012505(endomembrane system);GO:0012505(endomembrane system)","04142(Lysosome);04142(Lysosome)","K12387","NA","lysosomal protein transmembrane 4 alpha [Source:HGNC Symbol;Acc:HGNC:6924]",{"v":4.04735911664954,"d":"4.05"},{"v":13.9802602517986,"d":"13.98"},{"v":0.289505276994313,"d":"0.29"},{"v":-1.78833844952556,"d":"-1.79"},{"v":0.00920279009354105,"d":"0.01"},{"v":0.300090542742956,"d":"0.30"},"down","yes"]
["ENSG00000158887","MPZ","ENST00000526189;ENST00000533357;ENST00000476410;ENST00000491222;ENST00000488271;ENST00000463290","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005887(integral component of plasma membrane);GO:0005886(plasma membrane);GO:0043209(myelin sheath);GO:0007268(chemical synaptic transmission);GO:0005198(structural molecule activity);GO:0042552(myelination);GO:0098742(cell-cell adhesion via plasma-membrane adhesion molecules);GO:0098743(cell aggregation);GO:0043066(negative regulation of apoptotic process);GO:0005764(lysosome);GO:0005791(rough endoplasmic reticulum);GO:0016323(basolateral plasma membrane);GO:0016323(basolateral plasma membrane)","04514(Cell adhesion molecules (CAMs));04514(Cell adhesion molecules (CAMs))","K06770","NA","myelin protein zero [Source:HGNC Symbol;Acc:HGNC:7225]",{"v":0.932454985143918,"d":"0.93"},{"v":3.28770404828227,"d":"3.29"},{"v":0.283618893747781,"d":"0.28"},{"v":-1.81797445156138,"d":"-1.82"},{"v":0.00925468626249203,"d":"0.01"},{"v":0.300090542742956,"d":"0.30"},"down","yes"]
["MSTRG.13281","VNN3","ENST00000425515;ENST00000367927;ENST00000414302;ENST00000427187;ENST00000580813;ENST00000448644;ENST00000544102;ENST00000392393;ENST00000423615;ENST00000275223;ENST00000450865;ENST00000519686;ENST00000509351;ENST00000417437","GO:0016020(membrane);GO:0016787(hydrolase activity);GO:0005886(plasma membrane);GO:0016810(hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds);GO:0006807(nitrogen compound metabolic process);GO:0016811(hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides);GO:0031225(anchored component of membrane);GO:0005576(extracellular region);GO:0008150(biological_process);GO:0005575(cellular_component);GO:0006501(C-terminal protein lipidation);GO:0017159(pantetheine hydrolase activity);GO:0015939(pantothenate metabolic process);GO:0015939(pantothenate metabolic process)","NA","NA","NA","vanin 3 [Source:HGNC Symbol;Acc:HGNC:16431]",{"v":2.25360370436817,"d":"2.25"},{"v":7.77609040587624,"d":"7.78"},{"v":0.289811921767932,"d":"0.29"},{"v":-1.78681115174646,"d":"-1.79"},{"v":0.00926524274200526,"d":"0.01"},{"v":0.300090542742956,"d":"0.30"},"down","yes"]
["MSTRG.1510","ZNF672","ENST00000306562;ENST00000505503;ENST00000515369;ENST00000502697;ENST00000428515","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0005654(nucleoplasm);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding)","NA","NA","NA","zinc finger protein 672 [Source:HGNC Symbol;Acc:HGNC:26179]",{"v":6.37735580326116,"d":"6.38"},{"v":1.91853171852446,"d":"1.92"},{"v":3.32408150549941,"d":"3.32"},{"v":1.73295575699941,"d":"1.73"},{"v":0.00927036056306092,"d":"0.01"},{"v":0.300090542742956,"d":"0.30"},"up","yes"]
["MSTRG.9167","TNFAIP6","ENST00000243347;ENST00000460812","GO:0007155(cell adhesion);GO:0005515(protein binding);GO:0005540(hyaluronic acid binding);GO:0005576(extracellular region);GO:0043312(neutrophil degranulation);GO:0006954(inflammatory response);GO:0007165(signal transduction);GO:0007267(cell-cell signaling);GO:1904813(ficolin-1-rich granule lumen);GO:1904724(tertiary granule lumen);GO:0030335(positive regulation of cell migration);GO:0030728(ovulation);GO:0050728(negative regulation of inflammatory response);GO:0005615(extracellular space);GO:0005615(extracellular space)","NA","NA","NA","TNF alpha induced protein 6 [Source:HGNC Symbol;Acc:HGNC:11898]",{"v":1.54390548955035,"d":"1.54"},{"v":5.40624458518049,"d":"5.41"},{"v":0.285578180051727,"d":"0.29"},{"v":-1.80804234217914,"d":"-1.81"},{"v":9.30713381223695E-3,"d":"0.01"},{"v":0.300473204737151,"d":"0.30"},"down","yes"]
["ENSG00000143067","ZNF697","ENST00000421812","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0003674(molecular_function);GO:0008150(biological_process);GO:0005575(cellular_component)","NA","NA","NA","zinc finger protein 697 [Source:HGNC Symbol;Acc:HGNC:32034]",{"v":0.192448,"d":"0.19"},{"v":0.698009,"d":"0.70"},{"v":0.275709912049845,"d":"0.28"},{"v":-1.85877696026286,"d":"-1.86"},{"v":0.00933855168187999,"d":"0.01"},{"v":0.300681388644917,"d":"0.30"},"down","yes"]
["ENSG00000171848","RRM2","ENST00000461327;ENST00000498343;ENST00000459969;ENST00000462343;ENST00000474701;ENST00000491447;ENST00000615152;ENST00000487591;ENST00000304567;ENST00000485717;ENST00000360566","GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0005829(cytosol);GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0005515(protein binding);GO:0006260(DNA replication);GO:0009263(deoxyribonucleotide biosynthetic process);GO:0004748(ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor);GO:0015949(nucleobase-containing small molecule interconversion);GO:0000083(regulation of transcription involved in G1/S transition of mitotic cell cycle);GO:0005971(ribonucleoside-diphosphate reductase complex);GO:0005971(ribonucleoside-diphosphate reductase complex)","00230(Purine metabolism);00240(Pyrimidine metabolism);00480(Glutathione metabolism);00983(Drug metabolism - other enzymes);04115(p53 signaling pathway);04115(p53 signaling pathway)","K10808","EC:1.17.4.1","ribonucleotide reductase regulatory subunit M2 [Source:HGNC Symbol;Acc:HGNC:10452]",{"v":1.51215321059553,"d":"1.51"},{"v":0.440539942325756,"d":"0.44"},{"v":3.43249967894483,"d":"3.43"},{"v":1.77925958543145,"d":"1.78"},{"v":0.00942867839835684,"d":"0.01"},{"v":0.302508153546908,"d":"0.30"},"up","yes"]
["ENSG00000131381","RBSN","ENST00000476527;ENST00000449050;ENST00000426541;ENST00000463214;ENST00000483098;ENST00000253699;ENST00000449964;ENST00000441057","GO:0003676(nucleic acid binding);GO:0006810(transport);GO:0016020(membrane);GO:0015031(protein transport);GO:0005829(cytosol);GO:0043231(intracellular membrane-bounded organelle);GO:0046872(metal ion binding);GO:0008270(zinc ion binding);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0017137(Rab GTPase binding);GO:0005768(endosome);GO:0070062(extracellular exosome);GO:0010008(endosome membrane);GO:0016197(endosomal transport);GO:0031901(early endosome membrane);GO:0006895(Golgi to endosome transport);GO:0007596(blood coagulation);GO:0090160(Golgi to lysosome transport);GO:0006897(endocytosis);GO:0034498(early endosome to Golgi transport);GO:1903358(regulation of Golgi organization);GO:0034058(endosomal vesicle fusion);GO:0000011(vacuole inheritance);GO:0010009(cytoplasmic side of endosome membrane);GO:0010009(cytoplasmic side of endosome membrane)","04144(Endocytosis);04144(Endocytosis)","K12481","NA","rabenosyn, RAB effector [Source:HGNC Symbol;Acc:HGNC:20759]",{"v":0.312971449438202,"d":"0.31"},{"v":1.09931020628708,"d":"1.10"},{"v":0.284698029408153,"d":"0.28"},{"v":-1.8124955876622,"d":"-1.81"},{"v":0.00944552945803334,"d":"0.01"},{"v":0.302508153546908,"d":"0.30"},"down","yes"]
["MSTRG.10347","UQCR10","ENST00000330029;ENST00000401406","GO:0016020(membrane);GO:0055114(oxidation-reduction process);GO:0005743(mitochondrial inner membrane);GO:0005739(mitochondrion);GO:1902600(hydrogen ion transmembrane transport);GO:0070469(respiratory chain);GO:0008121(ubiquinol-cytochrome-c reductase activity);GO:0006122(mitochondrial electron transport, ubiquinol to cytochrome c);GO:0009060(aerobic respiration);GO:0005750(mitochondrial respiratory chain complex III);GO:0070062(extracellular exosome);GO:0034551(mitochondrial respiratory chain complex III assembly);GO:0034551(mitochondrial respiratory chain complex III assembly)","00190(Oxidative phosphorylation);04260(Cardiac muscle contraction);05010(Alzheimer's disease);05012(Parkinson's disease);05016(Huntington's disease);04932(Non-alcoholic fatty liver disease (NAFLD));04932(Non-alcoholic fatty liver disease (NAFLD))","K00419","NA","ubiquinol-cytochrome c reductase, complex III subunit X [Source:HGNC Symbol;Acc:HGNC:30863]",{"v":15.8938898830769,"d":"15.89"},{"v":4.78353455589744,"d":"4.78"},{"v":3.32262466118948,"d":"3.32"},{"v":1.73232332883357,"d":"1.73"},{"v":0.00961621365791702,"d":"0.01"},{"v":0.306626027934348,"d":"0.31"},"up","yes"]
["MSTRG.15373","CYSLTR1","ENST00000373304;ENST00000493254","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0004930(G-protein coupled receptor activity);GO:0007186(G-protein coupled receptor signaling pathway);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0004871(signal transducer activity);GO:0007165(signal transduction);GO:0005887(integral component of plasma membrane);GO:0004974(leukotriene receptor activity);GO:0061737(leukotriene signaling pathway);GO:0006952(defense response);GO:0007200(phospholipase C-activating G-protein coupled receptor signaling pathway);GO:0007204(positive regulation of cytosolic calcium ion concentration);GO:0007585(respiratory gaseous exchange);GO:0007218(neuropeptide signaling pathway);GO:0008528(G-protein coupled peptide receptor activity);GO:0003013(circulatory system process);GO:0002437(inflammatory response to antigenic stimulus);GO:0006816(calcium ion transport);GO:0006935(chemotaxis);GO:0007166(cell surface receptor signaling pathway);GO:0007166(cell surface receptor signaling pathway)","04020(Calcium signaling pathway);04080(Neuroactive ligand-receptor interaction);04080(Neuroactive ligand-receptor interaction)","K04322","NA","cysteinyl leukotriene receptor 1 [Source:HGNC Symbol;Acc:HGNC:17451]",{"v":0.544472772572249,"d":"0.54"},{"v":1.88866432202477,"d":"1.89"},{"v":0.288284565035114,"d":"0.29"},{"v":-1.79443449892658,"d":"-1.79"},{"v":0.00962503226699747,"d":"0.01"},{"v":0.306626027934348,"d":"0.31"},"down","yes"]
["MSTRG.3292","IRAK4","ENST00000547521;ENST00000552309;ENST00000547101;ENST00000550616;ENST00000613694;ENST00000448290;ENST00000550361;ENST00000547928;ENST00000550386;ENST00000431837;ENST00000546780;ENST00000550615;ENST00000551736;ENST00000440781","GO:0005737(cytoplasm);GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0016740(transferase activity);GO:0000287(magnesium ion binding);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0007165(signal transduction);GO:0005515(protein binding);GO:0002376(immune system process);GO:0045087(innate immune response);GO:0005886(plasma membrane);GO:0005634(nucleus);GO:0005829(cytosol);GO:0010008(endosome membrane);GO:0002224(toll-like receptor signaling pathway);GO:0002755(MyD88-dependent toll-like receptor signaling pathway);GO:0034162(toll-like receptor 9 signaling pathway);GO:0043123(positive regulation of I-kappaB kinase/NF-kappaB signaling);GO:0002446(neutrophil mediated immunity);GO:0051092(positive regulation of NF-kappaB transcription factor activity);GO:0070498(interleukin-1-mediated signaling pathway);GO:1990266(neutrophil migration);GO:0005622(intracellular);GO:0005149(interleukin-1 receptor binding);GO:0001816(cytokine production);GO:0007254(JNK cascade);GO:0019221(cytokine-mediated signaling pathway);GO:0048661(positive regulation of smooth muscle cell proliferation);GO:0005615(extracellular space);GO:0005615(extracellular space)","04010(MAPK signaling pathway);04064(NF-kappa B signaling pathway);04620(Toll-like receptor signaling pathway);04621(NOD-like receptor signaling pathway);04722(Neurotrophin signaling pathway);05133(Pertussis);05152(Tuberculosis);05162(Measles);05164(Influenza A);05145(Toxoplasmosis);05140(Leishmaniasis);05142(Chagas disease (American trypanosomiasis));05142(Chagas disease (American trypanosomiasis))","K04733","EC:2.7.11.1","interleukin 1 receptor associated kinase 4 [Source:HGNC Symbol;Acc:HGNC:17967]",{"v":1.08924441215136,"d":"1.09"},{"v":3.73221205169657,"d":"3.73"},{"v":0.291849551167977,"d":"0.29"},{"v":-1.77670324536939,"d":"-1.78"},{"v":0.00972162827362548,"d":"0.01"},{"v":0.308510326733966,"d":"0.31"},"down","yes"]
["ENSG00000197208","SLC22A4","ENST00000200652;ENST00000491257;ENST00000425923","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005215(transporter activity);GO:0055085(transmembrane transport);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0034220(ion transmembrane transport);GO:0098655(cation transmembrane transport);GO:0015293(symporter activity);GO:0006811(ion transport);GO:0006814(sodium ion transport);GO:0022857(transmembrane transporter activity);GO:0005886(plasma membrane);GO:0015711(organic anion transport);GO:0008514(organic anion transmembrane transporter activity);GO:0005515(protein binding);GO:0005887(integral component of plasma membrane);GO:0005739(mitochondrion);GO:0007589(body fluid secretion);GO:0015695(organic cation transport);GO:0030165(PDZ domain binding);GO:1902603(carnitine transmembrane transport);GO:0016324(apical plasma membrane);GO:0015651(quaternary ammonium group transmembrane transporter activity);GO:0009437(carnitine metabolic process);GO:0015697(quaternary ammonium group transport);GO:0015226(carnitine transmembrane transporter activity);GO:0015879(carnitine transport);GO:0008513(secondary active organic cation transmembrane transporter activity);GO:0015491(cation:cation antiporter activity);GO:0006641(triglyceride metabolic process);GO:0006641(triglyceride metabolic process)","05231(Choline metabolism in cancer);05231(Choline metabolism in cancer)","K08202","NA","solute carrier family 22 member 4 [Source:HGNC Symbol;Acc:HGNC:10968]",{"v":0.798827470238095,"d":"0.80"},{"v":2.79750638578869,"d":"2.80"},{"v":0.285549829053521,"d":"0.29"},{"v":-1.80818557397271,"d":"-1.81"},{"v":0.00973541971092071,"d":"0.01"},{"v":0.308510326733966,"d":"0.31"},"down","yes"]
["MSTRG.7908","ADGRE3","ENST00000344373;ENST00000253673;ENST00000595472;ENST00000443157;ENST00000599900","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0004930(G-protein coupled receptor activity);GO:0007186(G-protein coupled receptor signaling pathway);GO:0004888(transmembrane signaling receptor activity);GO:0007166(cell surface receptor signaling pathway);GO:0005509(calcium ion binding);GO:0005886(plasma membrane);GO:0004871(signal transducer activity);GO:0007165(signal transduction);GO:0005576(extracellular region);GO:0043312(neutrophil degranulation);GO:0030667(secretory granule membrane);GO:0101003(ficolin-1-rich granule membrane);GO:0101003(ficolin-1-rich granule membrane)","NA","NA","NA","adhesion G protein-coupled receptor E3 [Source:HGNC Symbol;Acc:HGNC:23647]",{"v":8.78480963905534,"d":"8.78"},{"v":29.8040352611914,"d":"29.80"},{"v":0.2947523569231,"d":"0.29"},{"v":-1.76242474543916,"d":"-1.76"},{"v":0.00989442784740918,"d":"0.01"},{"v":0.312726247082681,"d":"0.31"},"down","yes"]
["MSTRG.5346","BCL2A1","ENST00000267953;ENST00000335661;MSTRG.5346.1","GO:0005737(cytoplasm);GO:0043066(negative regulation of apoptotic process);GO:0042981(regulation of apoptotic process);GO:0055085(transmembrane transport);GO:0005515(protein binding);GO:0006915(apoptotic process);GO:0042803(protein homodimerization activity);GO:0043065(positive regulation of apoptotic process);GO:0008630(intrinsic apoptotic signaling pathway in response to DNA damage);GO:0046982(protein heterodimerization activity);GO:0097192(extrinsic apoptotic signaling pathway in absence of ligand);GO:0005741(mitochondrial outer membrane);GO:0015267(channel activity);GO:0051400(BH domain binding);GO:0001836(release of cytochrome c from mitochondria);GO:0007568(aging);GO:0008053(mitochondrial fusion);GO:0021987(cerebral cortex development);GO:0021987(cerebral cortex development)","04064(NF-kappa B signaling pathway);04210(Apoptosis);05202(Transcriptional misregulation in cancers);05221(Acute myeloid leukemia);05221(Acute myeloid leukemia)","K02162","NA","BCL2 related protein A1 [Source:HGNC Symbol;Acc:HGNC:991]",{"v":10.744686447944,"d":"10.74"},{"v":36.4785953158355,"d":"36.48"},{"v":0.294547702698401,"d":"0.29"},{"v":-1.76342679402924,"d":"-1.76"},{"v":0.00994864601575265,"d":"0.01"},{"v":0.313616741679826,"d":"0.31"},"down","yes"]
["ENSG00000223804","AC244669.1","ENST00000613290;ENST00000621564;ENST00000616141;ENST00000617318","NA","NA","NA","NA",null,{"v":2.0978292601626,"d":"2.10"},{"v":0.601368230352304,"d":"0.60"},{"v":3.4884271470969,"d":"3.49"},{"v":1.8025767044693,"d":"1.80"},{"v":0.00998632947181984,"d":"0.01"},{"v":0.313982714098315,"d":"0.31"},"up","yes"]
["MSTRG.13148","CYB5R4","ENST00000369681;ENST00000369679;ENST00000479164","GO:0046872(metal ion binding);GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0005783(endoplasmic reticulum);GO:0048471(perinuclear region of cytoplasm);GO:0020037(heme binding);GO:0004128(cytochrome-b5 reductase activity, acting on NAD(P)H);GO:0005789(endoplasmic reticulum membrane);GO:0006801(superoxide metabolic process);GO:0016174(NAD(P)H oxidase activity);GO:0042593(glucose homeostasis);GO:0015701(bicarbonate transport);GO:0046677(response to antibiotic);GO:0006091(generation of precursor metabolites and energy);GO:0030073(insulin secretion);GO:0048468(cell development);GO:0016653(oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor);GO:0003032(detection of oxygen);GO:0003032(detection of oxygen)","00520(Amino sugar and nucleotide sugar metabolism);00520(Amino sugar and nucleotide sugar metabolism)","K00326","EC:1.6.2.2","cytochrome b5 reductase 4 [Source:HGNC Symbol;Acc:HGNC:20147]",{"v":1.66432431053451,"d":"1.66"},{"v":5.63216636886352,"d":"5.63"},{"v":0.295503399852576,"d":"0.30"},{"v":-1.75875336576295,"d":"-1.76"},{"v":0.0101147429777493,"d":"0.01"},{"v":0.316376116136891,"d":"0.32"},"down","yes"]
["MSTRG.11940","ACSL1","ENST00000281455;ENST00000503407;MSTRG.11940.1;ENST00000454703;ENST00000515030;ENST00000513317;ENST00000513001;ENST00000622937;ENST00000507295;ENST00000504342;ENST00000505492;ENST00000504900","GO:0003824(catalytic activity);GO:0008152(metabolic process);GO:0016874(ligase activity);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0006629(lipid metabolic process);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0006631(fatty acid metabolic process);GO:0005739(mitochondrion);GO:0005741(mitochondrial outer membrane);GO:0005777(peroxisome);GO:0005778(peroxisomal membrane);GO:0043231(intracellular membrane-bounded organelle);GO:0035338(long-chain fatty-acyl-CoA biosynthetic process);GO:0031090(organelle membrane);GO:0036109(alpha-linolenic acid metabolic process);GO:0004467(long-chain fatty acid-CoA ligase activity);GO:0102391(decanoate--CoA ligase activity);GO:0001676(long-chain fatty acid metabolic process);GO:0044539(long-chain fatty acid import);GO:0019216(regulation of lipid metabolic process);GO:0043651(linoleic acid metabolic process);GO:0006641(triglyceride metabolic process);GO:0007584(response to nutrient);GO:0008610(lipid biosynthetic process);GO:0010033(response to organic substance);GO:0014070(response to organic cyclic compound);GO:0015908(fatty acid transport);GO:0033211(adiponectin-activated signaling pathway);GO:0034201(response to oleic acid);GO:0042178(xenobiotic catabolic process);GO:0042493(response to drug);GO:0071902(positive regulation of protein serine/threonine kinase activity);GO:0005886(plasma membrane);GO:0005886(plasma membrane)","00061(Fatty acid biosynthesis);00071(Fatty acid degradation);04146(Peroxisome);04216(Ferroptosis);04920(Adipocytokine signaling pathway);03320(PPAR signaling pathway);03320(PPAR signaling pathway)","K01897","EC:6.2.1.3","acyl-CoA synthetase long chain family member 1 [Source:HGNC Symbol;Acc:HGNC:3569]",{"v":11.2046063594041,"d":"11.20"},{"v":37.8361868302297,"d":"37.84"},{"v":0.296134660970963,"d":"0.30"},{"v":-1.75567473478599,"d":"-1.76"},{"v":0.010114997900075,"d":"0.01"},{"v":0.316376116136891,"d":"0.32"},"down","yes"]
["ENSG00000197045","GMFB","ENST00000358056;ENST00000616146;ENST00000553952;ENST00000553333;ENST00000554682;ENST00000553566;ENST00000554163;ENST00000628554;ENST00000554908","GO:0071933(Arp2/3 complex binding);GO:0034316(negative regulation of Arp2/3 complex-mediated actin nucleation);GO:0003779(actin binding);GO:0005622(intracellular);GO:0008083(growth factor activity);GO:0043085(positive regulation of catalytic activity);GO:0006469(negative regulation of protein kinase activity);GO:0006468(protein phosphorylation);GO:0007399(nervous system development);GO:0004871(signal transducer activity);GO:0007165(signal transduction);GO:0004860(protein kinase inhibitor activity);GO:0008047(enzyme activator activity);GO:0007612(learning);GO:0007626(locomotory behavior);GO:0007626(locomotory behavior)","NA","NA","NA","glia maturation factor beta [Source:HGNC Symbol;Acc:HGNC:4373]",{"v":1.23576734019583,"d":"1.24"},{"v":0.372276375470751,"d":"0.37"},{"v":3.31948901842933,"d":"3.32"},{"v":1.73096117912811,"d":"1.73"},{"v":0.0101816513278001,"d":"0.01"},{"v":0.317635868625307,"d":"0.32"},"up","yes"]
["ENSG00000170486","KRT72","ENST00000550829;ENST00000537672;ENST00000293745","GO:0005198(structural molecule activity);GO:0005515(protein binding);GO:0005882(intermediate filament);GO:0045095(keratin filament);GO:0003674(molecular_function);GO:0008150(biological_process);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0031424(keratinization);GO:0070268(cornification);GO:0070268(cornification)","NA","NA","NA","keratin 72 [Source:HGNC Symbol;Acc:HGNC:28932]",{"v":1.08255167130919,"d":"1.08"},{"v":0.307129571494893,"d":"0.31"},{"v":3.52473930152698,"d":"3.52"},{"v":1.81751655614893,"d":"1.82"},{"v":0.0102842954058708,"d":"0.01"},{"v":0.320009005885002,"d":"0.32"},"up","yes"]
["MSTRG.3455","ANKRD52","ENST00000267116;ENST00000548081;ENST00000548241","GO:0005515(protein binding);GO:0005515(protein binding)","NA","NA","NA","ankyrin repeat domain 52 [Source:HGNC Symbol;Acc:HGNC:26614]",{"v":1.22707067539683,"d":"1.23"},{"v":4.14689003877551,"d":"4.15"},{"v":0.29590142586929,"d":"0.30"},{"v":-1.75681144637987,"d":"-1.76"},{"v":0.0103421805784873,"d":"0.01"},{"v":0.320463209994302,"d":"0.32"},"down","yes"]
["MSTRG.15213","GK","ENST00000378945;ENST00000378946;ENST00000427190;ENST00000378941;ENST00000378943;ENST00000481024;ENST00000425166;ENST00000479048;ENST00000378938;ENST00000487652","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0016773(phosphotransferase activity, alcohol group as acceptor);GO:0005975(carbohydrate metabolic process);GO:0005739(mitochondrion);GO:0005515(protein binding);GO:0006072(glycerol-3-phosphate metabolic process);GO:0005741(mitochondrial outer membrane);GO:0004370(glycerol kinase activity);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0019432(triglyceride biosynthetic process);GO:0006641(triglyceride metabolic process);GO:0006071(glycerol metabolic process);GO:0019563(glycerol catabolic process);GO:0046167(glycerol-3-phosphate biosynthetic process);GO:0046167(glycerol-3-phosphate biosynthetic process)","00561(Glycerolipid metabolism);03320(PPAR signaling pathway);03320(PPAR signaling pathway)","K00864","EC:2.7.1.30","glycerol kinase [Source:HGNC Symbol;Acc:HGNC:4289]",{"v":1.37056437395036,"d":"1.37"},{"v":4.64772886545997,"d":"4.65"},{"v":0.294889055197655,"d":"0.29"},{"v":-1.76175581709635,"d":"-1.76"},{"v":0.0103543179441817,"d":"0.01"},{"v":0.320463209994302,"d":"0.32"},"down","yes"]
["MSTRG.1694","MARCH8","ENST00000453424;MSTRG.1694.2;ENST00000319836;ENST00000476962;ENST00000451376;ENST00000453980;ENST00000602712","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0016740(transferase activity);GO:0016567(protein ubiquitination);GO:0005765(lysosomal membrane);GO:0030659(cytoplasmic vesicle membrane);GO:0031410(cytoplasmic vesicle);GO:0002376(immune system process);GO:0005764(lysosome);GO:0002250(adaptive immune response);GO:0005768(endosome);GO:0031901(early endosome membrane);GO:0004842(ubiquitin-protein transferase activity);GO:0000209(protein polyubiquitination);GO:0000209(protein polyubiquitination)","NA","NA","NA","membrane associated ring-CH-type finger 8 [Source:HGNC Symbol;Acc:HGNC:23356]",{"v":24.7019618119114,"d":"24.70"},{"v":7.62134774585489,"d":"7.62"},{"v":3.24115401050245,"d":"3.24"},{"v":1.69650757508621,"d":"1.70"},{"v":0.0103787287741055,"d":"0.01"},{"v":0.320463209994302,"d":"0.32"},"up","yes"]
["MSTRG.278","SH3BGRL3","ENST00000270792;ENST00000319041","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0045454(cell redox homeostasis);GO:0055114(oxidation-reduction process);GO:0016604(nuclear body);GO:0005096(GTPase activator activity);GO:0009055(electron carrier activity);GO:0015035(protein disulfide oxidoreductase activity);GO:0030027(lamellipodium);GO:0070062(extracellular exosome);GO:0032956(regulation of actin cytoskeleton organization);GO:0043547(positive regulation of GTPase activity);GO:0030215(semaphorin receptor binding);GO:0030834(regulation of actin filament depolymerization);GO:0043535(regulation of blood vessel endothelial cell migration);GO:0043535(regulation of blood vessel endothelial cell migration)","NA","NA","NA","SH3 domain binding glutamate rich protein like 3 [Source:HGNC Symbol;Acc:HGNC:15568]",{"v":330.339649513438,"d":"330.34"},{"v":102.429650120941,"d":"102.43"},{"v":3.22503932331506,"d":"3.23"},{"v":1.68931675160745,"d":"1.69"},{"v":0.01062614067308,"d":"0.01"},{"v":0.327263391266571,"d":"0.33"},"up","yes"]
["MSTRG.5058","AC023355.1","MSTRG.5058.1","NA","NA","NA","NA",null,{"v":0.23531,"d":"0.24"},{"v":0.849615,"d":"0.85"},{"v":0.276960741041531,"d":"0.28"},{"v":-1.85224660496218,"d":"-1.85"},{"v":0.0108201638472168,"d":"0.01"},{"v":0.332388808796388,"d":"0.33"},"down","yes"]
["ENSG00000168495","POLR3D","ENST00000397802;ENST00000519237;ENST00000306433;ENST00000518039","GO:0005634(nucleus);GO:0016607(nuclear speck);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0003677(DNA binding);GO:0003899(DNA-directed 5'-3' RNA polymerase activity);GO:0006383(transcription from RNA polymerase III promoter);GO:0002376(immune system process);GO:0045087(innate immune response);GO:0051607(defense response to virus);GO:0005666(DNA-directed RNA polymerase III complex);GO:0032728(positive regulation of interferon-beta production);GO:0045089(positive regulation of innate immune response);GO:0001056(RNA polymerase III activity);GO:0032481(positive regulation of type I interferon production);GO:0000790(nuclear chromatin);GO:0003682(chromatin binding);GO:0003682(chromatin binding)","00230(Purine metabolism);00240(Pyrimidine metabolism);03020(RNA polymerase);04623(Cytosolic DNA-sensing pathway);05169(Epstein-Barr virus infection);05169(Epstein-Barr virus infection)","K03026","NA","RNA polymerase III subunit D [Source:HGNC Symbol;Acc:HGNC:1080]",{"v":1.76971325859918,"d":"1.77"},{"v":0.541607939404741,"d":"0.54"},{"v":3.2675172017312,"d":"3.27"},{"v":1.7081948310588,"d":"1.71"},{"v":0.0108613980366848,"d":"0.01"},{"v":0.332806501673687,"d":"0.33"},"up","yes"]
["MSTRG.2253","ZBED5","ENST00000413761;ENST00000432999;ENST00000530570;ENST00000533903;ENST00000534690;ENST00000525350;ENST00000526020;ENST00000533925","GO:0003676(nucleic acid binding);GO:0046872(metal ion binding);GO:0003677(DNA binding);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0005737(cytoplasm);GO:0000981(RNA polymerase II transcription factor activity, sequence-specific DNA binding);GO:0005654(nucleoplasm);GO:0005654(nucleoplasm)","NA","NA","NA","zinc finger BED-type containing 5 [Source:HGNC Symbol;Acc:HGNC:30803]",{"v":2.42532579178204,"d":"2.43"},{"v":0.74646460338908,"d":"0.75"},{"v":3.24908345388467,"d":"3.25"},{"v":1.70003280028768,"d":"1.70"},{"v":0.0108986466070504,"d":"0.01"},{"v":0.333100260005332,"d":"0.33"},"up","yes"]
["MSTRG.2308","PRRG4","ENST00000257836","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005509(calcium ion binding);GO:0005576(extracellular region);GO:0003674(molecular_function);GO:0008150(biological_process)","NA","NA","NA","proline rich and Gla domain 4 [Source:HGNC Symbol;Acc:HGNC:30799]",{"v":1.309621,"d":"1.31"},{"v":4.38579,"d":"4.39"},{"v":0.298605496387196,"d":"0.30"},{"v":-1.74368737369632,"d":"-1.74"},{"v":0.0109693598654984,"d":"0.01"},{"v":0.33325132883252,"d":"0.33"},"down","yes"]
["MSTRG.9436","CYP27A1","ENST00000258415;ENST00000494263;ENST00000466602;ENST00000411688","GO:0016020(membrane);GO:0046872(metal ion binding);GO:0004497(monooxygenase activity);GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0005739(mitochondrion);GO:0005506(iron ion binding);GO:0016705(oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen);GO:0020037(heme binding);GO:0031966(mitochondrial membrane);GO:0005759(mitochondrial matrix);GO:0006699(bile acid biosynthetic process);GO:0016125(sterol metabolic process);GO:0008395(steroid hydroxylase activity);GO:0005743(mitochondrial inner membrane);GO:0005743(mitochondrial inner membrane)","00120(Primary bile acid biosynthesis);03320(PPAR signaling pathway);04979(Cholesterol metabolism);04979(Cholesterol metabolism)","K00488","EC:1.14.15.15","cytochrome P450 family 27 subfamily A member 1 [Source:HGNC Symbol;Acc:HGNC:2605]",{"v":2.49899949312772,"d":"2.50"},{"v":8.38079727522628,"d":"8.38"},{"v":0.298181594311413,"d":"0.30"},{"v":-1.74573688694799,"d":"-1.75"},{"v":0.0109709722130448,"d":"0.01"},{"v":0.33325132883252,"d":"0.33"},"down","yes"]
["MSTRG.1947","SFXN2","ENST00000369893;ENST00000602647;ENST00000602287;ENST00000602660;ENST00000602544;ENST00000602785;ENST00000602831;ENST00000602670;ENST00000459894","GO:0055085(transmembrane transport);GO:0016020(membrane);GO:0006811(ion transport);GO:0034220(ion transmembrane transport);GO:0015075(ion transmembrane transporter activity);GO:0006810(transport);GO:0016021(integral component of membrane);GO:0005739(mitochondrion);GO:0031966(mitochondrial membrane);GO:0055072(iron ion homeostasis);GO:0005743(mitochondrial inner membrane);GO:0005743(mitochondrial inner membrane)","NA","NA","NA","sideroflexin 2 [Source:HGNC Symbol;Acc:HGNC:16086]",{"v":0.489081545058501,"d":"0.49"},{"v":0.142919832337565,"d":"0.14"},{"v":3.42206912126324,"d":"3.42"},{"v":1.77486890065041,"d":"1.77"},{"v":0.0109866116547509,"d":"0.01"},{"v":0.33325132883252,"d":"0.33"},"up","yes"]
["MSTRG.10380","TUG1","ENST00000540687;ENST00000519077;ENST00000569149;ENST00000566220;ENST00000602971;ENST00000563812;ENST00000569384;ENST00000602393","NA","NA","NA","NA","taurine up-regulated 1 (non-protein coding) [Source:HGNC Symbol;Acc:HGNC:26066]",{"v":6.6745851121743,"d":"6.67"},{"v":2.07161324701899,"d":"2.07"},{"v":3.22192625567484,"d":"3.22"},{"v":1.68792347362557,"d":"1.69"},{"v":0.0110314452028014,"d":"0.01"},{"v":0.333419253945498,"d":"0.33"},"up","yes"]
["ENSG00000176890","TYMS","ENST00000323274;ENST00000581920;ENST00000579128","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0008168(methyltransferase activity);GO:0016740(transferase activity);GO:0032259(methylation);GO:0005743(mitochondrial inner membrane);GO:0005739(mitochondrion);GO:0005759(mitochondrial matrix);GO:0005829(cytosol);GO:0015949(nucleobase-containing small molecule interconversion);GO:0071897(DNA biosynthetic process);GO:0009165(nucleotide biosynthetic process);GO:0000083(regulation of transcription involved in G1/S transition of mitotic cell cycle);GO:0046683(response to organophosphorus);GO:0000900(translation repressor activity, nucleic acid binding);GO:0005542(folic acid binding);GO:1990825(sequence-specific mRNA binding);GO:0017148(negative regulation of translation);GO:0000166(nucleotide binding);GO:0003729(mRNA binding);GO:0004799(thymidylate synthase activity);GO:0008144(drug binding);GO:0042803(protein homodimerization activity);GO:0048037(cofactor binding);GO:0006206(pyrimidine nucleobase metabolic process);GO:0006231(dTMP biosynthetic process);GO:0006235(dTTP biosynthetic process);GO:0006417(regulation of translation);GO:0007568(aging);GO:0007623(circadian rhythm);GO:0008283(cell proliferation);GO:0009636(response to toxic substance);GO:0014070(response to organic cyclic compound);GO:0016049(cell growth);GO:0019088(immortalization of host cell by virus);GO:0019860(uracil metabolic process);GO:0032570(response to progesterone);GO:0033189(response to vitamin A);GO:0034097(response to cytokine);GO:0035999(tetrahydrofolate interconversion);GO:0042493(response to drug);GO:0045471(response to ethanol);GO:0046078(dUMP metabolic process);GO:0046653(tetrahydrofolate metabolic process);GO:0048589(developmental growth);GO:0051216(cartilage development);GO:0051384(response to glucocorticoid);GO:0051593(response to folic acid);GO:0060574(intestinal epithelial cell maturation);GO:0097421(liver regeneration);GO:0005730(nucleolus);GO:0005730(nucleolus)","00240(Pyrimidine metabolism);00670(One carbon pool by folate);01523(Antifolate resistance);01523(Antifolate resistance)","K00560","EC:2.1.1.45","thymidylate synthetase [Source:HGNC Symbol;Acc:HGNC:12441]",{"v":1.4320310048583,"d":"1.43"},{"v":0.427238295546559,"d":"0.43"},{"v":3.35183203328327,"d":"3.35"},{"v":1.74494985463964,"d":"1.74"},{"v":0.0110576884402878,"d":"0.01"},{"v":0.333419253945498,"d":"0.33"},"up","yes"]
["MSTRG.2704","KCNE3","ENST00000525550;ENST00000310128;ENST00000531854;MSTRG.2704.2;ENST00000529425","GO:1903817(negative regulation of voltage-gated potassium channel activity);GO:0006810(transport);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0006811(ion transport);GO:0005244(voltage-gated ion channel activity);GO:0005249(voltage-gated potassium channel activity);GO:0005267(potassium channel activity);GO:0006813(potassium ion transport);GO:0034765(regulation of ion transmembrane transport);GO:0071805(potassium ion transmembrane transport);GO:0005886(plasma membrane);GO:0042995(cell projection);GO:0045121(membrane raft);GO:0030425(dendrite);GO:0005515(protein binding);GO:0043204(perikaryon);GO:0015459(potassium channel regulator activity);GO:0031982(vesicle);GO:0086091(regulation of heart rate by cardiac conduction);GO:0008076(voltage-gated potassium channel complex);GO:0032809(neuronal cell body membrane);GO:1902260(negative regulation of delayed rectifier potassium channel activity);GO:0044325(ion channel binding);GO:0043266(regulation of potassium ion transport);GO:1901387(positive regulation of voltage-gated calcium channel activity);GO:1903765(negative regulation of potassium ion export across plasma membrane);GO:1905025(negative regulation of membrane repolarization during ventricular cardiac muscle cell action potential);GO:1905025(negative regulation of membrane repolarization during ventricular cardiac muscle cell action potential)","04974(Protein digestion and absorption);04974(Protein digestion and absorption)","K04897","NA","potassium voltage-gated channel subfamily E regulatory subunit 3 [Source:HGNC Symbol;Acc:HGNC:6243]",{"v":4.27572375719098,"d":"4.28"},{"v":14.2649108072039,"d":"14.26"},{"v":0.299737153283265,"d":"0.30"},{"v":-1.73823017374728,"d":"-1.74"},{"v":0.011075211889902,"d":"0.01"},{"v":0.333419253945498,"d":"0.33"},"down","yes"]
["MSTRG.5309","NEIL1","ENST00000355059;ENST00000567547;ENST00000569758;ENST00000569390;ENST00000565051;ENST00000568519;ENST00000564784;ENST00000564951;ENST00000564738;ENST00000567681;ENST00000569506;ENST00000561643;ENST00000568059","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0008270(zinc ion binding);GO:0005654(nucleoplasm);GO:0016787(hydrolase activity);GO:0016829(lyase activity);GO:0003677(DNA binding);GO:0005694(chromosome);GO:0003684(damaged DNA binding);GO:0005856(cytoskeleton);GO:0003824(catalytic activity);GO:0008152(metabolic process);GO:0016798(hydrolase activity, acting on glycosyl bonds);GO:0006281(DNA repair);GO:0006974(cellular response to DNA damage stimulus);GO:0003906(DNA-(apurinic or apyrimidinic site) lyase activity);GO:0016799(hydrolase activity, hydrolyzing N-glycosyl compounds);GO:0006284(base-excision repair);GO:0006289(nucleotide-excision repair);GO:0005815(microtubule organizing center);GO:0008022(protein C-terminus binding);GO:0006979(response to oxidative stress);GO:0045008(depyrimidination);GO:0019104(DNA N-glycosylase activity);GO:0032074(negative regulation of nuclease activity);GO:0032074(negative regulation of nuclease activity)","03410(Base excision repair);03410(Base excision repair)","K10567","EC:3.2.2.-;EC:4.2.99.18","nei like DNA glycosylase 1 [Source:HGNC Symbol;Acc:HGNC:18448]",{"v":0.640995910781205,"d":"0.64"},{"v":0.191295062265783,"d":"0.19"},{"v":3.35082308549404,"d":"3.35"},{"v":1.74451551810964,"d":"1.74"},{"v":0.0111543036052359,"d":"0.01"},{"v":0.33496290277868,"d":"0.33"},"up","yes"]
["MSTRG.11421","BCL6","MSTRG.11421.4;ENST00000406870;ENST00000621333;ENST00000232014;ENST00000438077;ENST00000419510;ENST00000479110;ENST00000430339;ENST00000470319","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0005794(Golgi apparatus);GO:0046872(metal ion binding);GO:0005654(nucleoplasm);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0005515(protein binding);GO:0006974(cellular response to DNA damage stimulus);GO:0002376(immune system process);GO:0006954(inflammatory response);GO:0042802(identical protein binding);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0043065(positive regulation of apoptotic process);GO:0043565(sequence-specific DNA binding);GO:0030308(negative regulation of cell growth);GO:0042127(regulation of cell proliferation);GO:0042981(regulation of apoptotic process);GO:0045892(negative regulation of transcription, DNA-templated);GO:0005657(replication fork);GO:0045591(positive regulation of regulatory T cell differentiation);GO:0003682(chromatin binding);GO:0050727(regulation of inflammatory response);GO:0000060(protein import into nucleus, translocation);GO:0042092(type 2 immune response);GO:0050776(regulation of immune response);GO:0000977(RNA polymerase II regulatory region sequence-specific DNA binding);GO:0001161(intronic transcription regulatory region sequence-specific DNA binding);GO:0001227(transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding);GO:0031490(chromatin DNA binding);GO:0000902(cell morphogenesis);GO:0001953(negative regulation of cell-matrix adhesion);GO:0002467(germinal center formation);GO:0002634(regulation of germinal center formation);GO:0002829(negative regulation of type 2 immune response);GO:0002903(negative regulation of B cell apoptotic process);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0007266(Rho protein signal transduction);GO:0007283(spermatogenesis);GO:0008104(protein localization);GO:0008285(negative regulation of cell proliferation);GO:0030036(actin cytoskeleton organization);GO:0030183(B cell differentiation);GO:0030890(positive regulation of B cell proliferation);GO:0031065(positive regulation of histone deacetylation);GO:0032764(negative regulation of mast cell cytokine production);GO:0035024(negative regulation of Rho protein signal transduction);GO:0043066(negative regulation of apoptotic process);GO:0043087(regulation of GTPase activity);GO:0043380(regulation of memory T cell differentiation);GO:0045596(negative regulation of cell differentiation);GO:0045629(negative regulation of T-helper 2 cell differentiation);GO:0045666(positive regulation of neuron differentiation);GO:0045746(negative regulation of Notch signaling pathway);GO:0048294(negative regulation of isotype switching to IgE isotypes);GO:0048821(erythrocyte development);GO:0051272(positive regulation of cellular component movement);GO:1903464(negative regulation of mitotic cell cycle DNA replication);GO:2000773(negative regulation of cellular senescence);GO:2000773(negative regulation of cellular senescence)","04068(FoxO signaling pathway);05202(Transcriptional misregulation in cancers);05202(Transcriptional misregulation in cancers)","K15618","NA","B-cell CLL/lymphoma 6 [Source:HGNC Symbol;Acc:HGNC:1001]",{"v":6.58236209463398,"d":"6.58"},{"v":21.8259424187382,"d":"21.83"},{"v":0.301584324211487,"d":"0.30"},{"v":-1.72936665291902,"d":"-1.73"},{"v":0.0112360347231359,"d":"0.01"},{"v":0.336577935661698,"d":"0.34"},"down","yes"]
["MSTRG.10705","BTD","ENST00000494021;ENST00000467027;ENST00000471964;ENST00000417015;ENST00000303498;ENST00000449107;ENST00000482824;ENST00000383778;ENST00000480711","GO:0016787(hydrolase activity);GO:0016810(hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds);GO:0006807(nitrogen compound metabolic process);GO:0005576(extracellular region);GO:0005615(extracellular space);GO:0016811(hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides);GO:0070062(extracellular exosome);GO:0005759(mitochondrial matrix);GO:0007417(central nervous system development);GO:0006768(biotin metabolic process);GO:0047708(biotinidase activity);GO:0047708(biotinidase activity)","00780(Biotin metabolism);04977(Vitamin digestion and absorption);04977(Vitamin digestion and absorption)","K01435","EC:3.5.1.12","biotinidase [Source:HGNC Symbol;Acc:HGNC:1122]",{"v":0.373808042926566,"d":"0.37"},{"v":1.31771807046436,"d":"1.32"},{"v":0.28367831579849,"d":"0.28"},{"v":-1.81767221881019,"d":"-1.82"},{"v":0.0113245040608354,"d":"0.01"},{"v":0.338386297520049,"d":"0.34"},"down","yes"]
["MSTRG.11007","ARF4","ENST00000303436;ENST00000489843;ENST00000495354;ENST00000488156;ENST00000483848;ENST00000463880;ENST00000493378;ENST00000486310;ENST00000496292","GO:0006810(transport);GO:0016020(membrane);GO:0015031(protein transport);GO:0005525(GTP binding);GO:0007264(small GTPase mediated signal transduction);GO:0000166(nucleotide binding);GO:0005794(Golgi apparatus);GO:0005622(intracellular);GO:0005829(cytosol);GO:0043547(positive regulation of GTPase activity);GO:0005515(protein binding);GO:0016192(vesicle-mediated transport);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0070062(extracellular exosome);GO:0006890(retrograde vesicle-mediated transport, Golgi to ER);GO:0032587(ruffle membrane);GO:0003924(GTPase activity);GO:0031012(extracellular matrix);GO:0043066(negative regulation of apoptotic process);GO:0016477(cell migration);GO:0006888(ER to Golgi vesicle-mediated transport);GO:0005154(epidermal growth factor receptor binding);GO:2000377(regulation of reactive oxygen species metabolic process);GO:0043197(dendritic spine);GO:0006471(protein ADP-ribosylation);GO:0005086(ARF guanyl-nucleotide exchange factor activity);GO:0031584(activation of phospholipase D activity);GO:0060996(dendritic spine development);GO:0016021(integral component of membrane);GO:0016021(integral component of membrane)","NA","NA","NA","ADP ribosylation factor 4 [Source:HGNC Symbol;Acc:HGNC:655]",{"v":3.90490022312139,"d":"3.90"},{"v":12.9989961552987,"d":"13.00"},{"v":0.300400136785152,"d":"0.30"},{"v":-1.73504262511369,"d":"-1.74"},{"v":0.0115144831419746,"d":"0.01"},{"v":0.343211400979352,"d":"0.34"},"down","yes"]
["MSTRG.9412","CXCR1","ENST00000295683","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0004930(G-protein coupled receptor activity);GO:0007186(G-protein coupled receptor signaling pathway);GO:0005886(plasma membrane);GO:0004871(signal transducer activity);GO:0007165(signal transduction);GO:0006935(chemotaxis);GO:0070098(chemokine-mediated signaling pathway);GO:0016494(C-X-C chemokine receptor activity);GO:0043312(neutrophil degranulation);GO:0019959(interleukin-8 binding);GO:0006954(inflammatory response);GO:0030667(secretory granule membrane);GO:0004950(chemokine receptor activity);GO:0002407(dendritic cell chemotaxis);GO:0031623(receptor internalization);GO:0007166(cell surface receptor signaling pathway);GO:0004918(interleukin-8 receptor activity);GO:0038112(interleukin-8-mediated signaling pathway)","04072(Phospholipase D signaling pathway);04060(Cytokine-cytokine receptor interaction);04144(Endocytosis);04062(Chemokine signaling pathway);05120(Epithelial cell signaling in Helicobacter pylori infection)","K04175","NA","C-X-C motif chemokine receptor 1 [Source:HGNC Symbol;Acc:HGNC:6026]",{"v":79.614693,"d":"79.61"},{"v":262.457733,"d":"262.46"},{"v":0.303342911980422,"d":"0.30"},{"v":-1.72097849365388,"d":"-1.72"},{"v":0.0115708620669347,"d":"0.01"},{"v":0.343837558358027,"d":"0.34"},"down","yes"]
["MSTRG.3610","PLXNC1","ENST00000258526;ENST00000549810;ENST00000545312;MSTRG.3610.3;ENST00000546659;ENST00000551495;ENST00000550080;ENST00000547057;ENST00000549217;ENST00000546733","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0007165(signal transduction);GO:0005515(protein binding);GO:0017154(semaphorin receptor activity);GO:0071526(semaphorin-plexin signaling pathway);GO:0005886(plasma membrane);GO:0008360(regulation of cell shape);GO:0043087(regulation of GTPase activity);GO:0007155(cell adhesion);GO:0005102(receptor binding);GO:0007162(negative regulation of cell adhesion);GO:0050772(positive regulation of axonogenesis);GO:0050772(positive regulation of axonogenesis)","04360(Axon guidance);04360(Axon guidance)","K06572","NA","plexin C1 [Source:HGNC Symbol;Acc:HGNC:9106]",{"v":6.48345295630626,"d":"6.48"},{"v":21.3868214209568,"d":"21.39"},{"v":0.303151778784348,"d":"0.30"},{"v":-1.72188780721409,"d":"-1.72"},{"v":0.0115925966362198,"d":"0.01"},{"v":0.343837558358027,"d":"0.34"},"down","yes"]
["MSTRG.8393","NLRP12","ENST00000324134;ENST00000391775;ENST00000391773;ENST00000391772;ENST00000345770;ENST00000492915","GO:0050728(negative regulation of inflammatory response);GO:0005737(cytoplasm);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0007165(signal transduction);GO:0005515(protein binding);GO:0050718(positive regulation of interleukin-1 beta secretion);GO:0050729(positive regulation of inflammatory response);GO:0008656(cysteine-type endopeptidase activator activity involved in apoptotic process);GO:0006919(activation of cysteine-type endopeptidase activity involved in apoptotic process);GO:0032088(negative regulation of NF-kappaB transcription factor activity);GO:0008588(release of cytoplasmic sequestered NF-kappaB);GO:0043124(negative regulation of I-kappaB kinase/NF-kappaB signaling);GO:0009968(negative regulation of signal transduction);GO:0031953(negative regulation of protein autophosphorylation);GO:0043122(regulation of I-kappaB kinase/NF-kappaB signaling);GO:0043281(regulation of cysteine-type endopeptidase activity involved in apoptotic process);GO:0045345(positive regulation of MHC class I biosynthetic process);GO:0045381(regulation of interleukin-18 biosynthetic process);GO:0045409(negative regulation of interleukin-6 biosynthetic process);GO:0045751(negative regulation of Toll signaling pathway);GO:0050710(negative regulation of cytokine secretion);GO:0050711(negative regulation of interleukin-1 secretion);GO:0036336(dendritic cell migration);GO:0070373(negative regulation of ERK1 and ERK2 cascade);GO:0071345(cellular response to cytokine stimulus);GO:1901223(negative regulation of NIK/NF-kappaB signaling);GO:1901223(negative regulation of NIK/NF-kappaB signaling)","04621(NOD-like receptor signaling pathway);04621(NOD-like receptor signaling pathway)","K20865","NA","NLR family pyrin domain containing 12 [Source:HGNC Symbol;Acc:HGNC:22938]",{"v":4.6758633404088,"d":"4.68"},{"v":15.4296022146226,"d":"15.43"},{"v":0.303044970010795,"d":"0.30"},{"v":-1.72239619822684,"d":"-1.72"},{"v":0.0116605737179974,"d":"0.01"},{"v":0.34469279389823,"d":"0.34"},"down","yes"]
["ENSG00000165029","ABCA1","ENST00000374736;ENST00000374733;ENST00000494467","GO:0016021(integral component of membrane);GO:0006810(transport);GO:0005215(transporter activity);GO:0016020(membrane);GO:0005524(ATP binding);GO:0048471(perinuclear region of cytoplasm);GO:0042632(cholesterol homeostasis);GO:0000166(nucleotide binding);GO:0006629(lipid metabolic process);GO:0055085(transmembrane transport);GO:0008202(steroid metabolic process);GO:0005515(protein binding);GO:0016887(ATPase activity);GO:0008203(cholesterol metabolic process);GO:0098656(anion transmembrane transport);GO:0005886(plasma membrane);GO:0042626(ATPase activity, coupled to transmembrane movement of substances);GO:0005789(endoplasmic reticulum membrane);GO:0051117(ATPase binding);GO:0005102(receptor binding);GO:0034616(response to laminar fluid shear stress);GO:0033344(cholesterol efflux);GO:0019216(regulation of lipid metabolic process);GO:0005887(integral component of plasma membrane);GO:0045121(membrane raft);GO:0043231(intracellular membrane-bounded organelle);GO:0015485(cholesterol binding);GO:0005543(phospholipid binding);GO:0034380(high-density lipoprotein particle assembly);GO:0043691(reverse cholesterol transport);GO:0005548(phospholipid transporter activity);GO:0008509(anion transmembrane transporter activity);GO:0017127(cholesterol transporter activity);GO:0019905(syntaxin binding);GO:0031267(small GTPase binding);GO:0034185(apolipoprotein binding);GO:0034186(apolipoprotein A-I binding);GO:0034188(apolipoprotein A-I receptor activity);GO:0090554(phosphatidylcholine-translocating ATPase activity);GO:0090556(phosphatidylserine-translocating ATPase activity);GO:0002790(peptide secretion);GO:0006497(protein lipidation);GO:0006911(phagocytosis, engulfment);GO:0007040(lysosome organization);GO:0007186(G-protein coupled receptor signaling pathway);GO:0007584(response to nutrient);GO:0010745(negative regulation of macrophage derived foam cell differentiation);GO:0010875(positive regulation of cholesterol efflux);GO:0010887(negative regulation of cholesterol storage);GO:0015914(phospholipid transport);GO:0015917(aminophospholipid transport);GO:0016197(endosomal transport);GO:0030301(cholesterol transport);GO:0030819(positive regulation of cAMP biosynthetic process);GO:0032367(intracellular cholesterol transport);GO:0032489(regulation of Cdc42 protein signal transduction);GO:0033700(phospholipid efflux);GO:0038027(apolipoprotein A-I-mediated signaling pathway);GO:0042157(lipoprotein metabolic process);GO:0042158(lipoprotein biosynthetic process);GO:0042493(response to drug);GO:0045332(phospholipid translocation);GO:0050702(interleukin-1 beta secretion);GO:0055091(phospholipid homeostasis);GO:0055098(response to low-density lipoprotein particle);GO:0060155(platelet dense granule organization);GO:0071222(cellular response to lipopolysaccharide);GO:0071300(cellular response to retinoic acid);GO:0071397(cellular response to cholesterol);GO:0090107(regulation of high-density lipoprotein particle assembly);GO:0005794(Golgi apparatus);GO:0009897(external side of plasma membrane);GO:0009986(cell surface);GO:0030139(endocytic vesicle);GO:0034364(high-density lipoprotein particle);GO:0045335(phagocytic vesicle);GO:0045335(phagocytic vesicle)","02010(ABC transporters);04975(Fat digestion and absorption);04979(Cholesterol metabolism);04979(Cholesterol metabolism)","K05641","NA","ATP binding cassette subfamily A member 1 [Source:HGNC Symbol;Acc:HGNC:29]",{"v":0.64794578907489,"d":"0.65"},{"v":2.14857484493392,"d":"2.15"},{"v":0.301570034017045,"d":"0.30"},{"v":-1.72943501483128,"d":"-1.73"},{"v":0.0116786796138912,"d":"0.01"},{"v":0.34469279389823,"d":"0.34"},"down","yes"]
["ENSG00000153933","DGKE","ENST00000284061;ENST00000572810;ENST00000571084;ENST00000572944;ENST00000576869","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0005634(nucleus);GO:0005829(cytosol);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0035556(intracellular signal transduction);GO:0008152(metabolic process);GO:0003951(NAD+ kinase activity);GO:0004143(diacylglycerol kinase activity);GO:0007205(protein kinase C-activating G-protein coupled receptor signaling pathway);GO:0005886(plasma membrane);GO:0030168(platelet activation);GO:0046834(lipid phosphorylation);GO:0008654(phospholipid biosynthetic process);GO:0008654(phospholipid biosynthetic process)","00561(Glycerolipid metabolism);00564(Glycerophospholipid metabolism);04070(Phosphatidylinositol signaling system);04072(Phospholipase D signaling pathway);05231(Choline metabolism in cancer);05231(Choline metabolism in cancer)","K00901","EC:2.7.1.107","diacylglycerol kinase epsilon [Source:HGNC Symbol;Acc:HGNC:2852]",{"v":0.166896918046282,"d":"0.17"},{"v":0.565864744900759,"d":"0.57"},{"v":0.294941361076581,"d":"0.29"},{"v":-1.76149994208464,"d":"-1.76"},{"v":0.011744074718857,"d":"0.01"},{"v":0.345775422407031,"d":"0.35"},"down","yes"]
["ENSG00000176896","TCEANC","ENST00000380600;ENST00000467590;ENST00000490617","GO:0005634(nucleus);GO:0006351(transcription, DNA-templated);GO:0005515(protein binding);GO:0005515(protein binding)","NA","NA","NA","transcription elongation factor A N-terminal and central domain containing [Source:HGNC Symbol;Acc:HGNC:28277]",{"v":0.180095316383101,"d":"0.18"},{"v":0.635326787612311,"d":"0.64"},{"v":0.283468791013734,"d":"0.28"},{"v":-1.81873818697976,"d":"-1.82"},{"v":0.011871020838618,"d":"0.01"},{"v":0.34866056814302,"d":"0.35"},"down","yes"]
["ENSG00000118113","MMP8","ENST00000532799;ENST00000438475;ENST00000528662;ENST00000236826;ENST00000533258","GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0016787(hydrolase activity);GO:0008233(peptidase activity);GO:0006508(proteolysis);GO:0005576(extracellular region);GO:0005578(proteinaceous extracellular matrix);GO:0005615(extracellular space);GO:0004222(metalloendopeptidase activity);GO:0008237(metallopeptidase activity);GO:0031012(extracellular matrix);GO:0004252(serine-type endopeptidase activity);GO:0030574(collagen catabolic process);GO:0043312(neutrophil degranulation);GO:0035580(specific granule lumen);GO:1904724(tertiary granule lumen);GO:0022617(extracellular matrix disassembly);GO:0035987(endodermal cell differentiation);GO:0035987(endodermal cell differentiation)","NA","NA","NA","matrix metallopeptidase 8 [Source:HGNC Symbol;Acc:HGNC:7175]",{"v":0.703941333333333,"d":"0.70"},{"v":2.36246660907504,"d":"2.36"},{"v":0.297968796946909,"d":"0.30"},{"v":-1.74676683415603,"d":"-1.75"},{"v":0.0119911362837974,"d":"0.01"},{"v":0.351331540461042,"d":"0.35"},"down","yes"]
["MSTRG.3895","FTH1P7","ENST00000450676","NA","NA","NA","NA","ferritin heavy chain 1 pseudogene 7 [Source:HGNC Symbol;Acc:HGNC:3994]",{"v":1.966402,"d":"1.97"},{"v":6.729496,"d":"6.73"},{"v":0.292206429723712,"d":"0.29"},{"v":-1.77494017126869,"d":"-1.77"},{"v":0.0121484003388529,"d":"0.01"},{"v":0.355075332234141,"d":"0.36"},"down","yes"]
["MSTRG.14189","PPP1R3B","ENST00000310455;ENST00000519699","GO:0050790(regulation of catalytic activity);GO:0019888(protein phosphatase regulator activity);GO:0006470(protein dephosphorylation);GO:0005975(carbohydrate metabolic process);GO:0005977(glycogen metabolic process);GO:0004721(phosphoprotein phosphatase activity);GO:0019899(enzyme binding);GO:0005979(regulation of glycogen biosynthetic process);GO:0005981(regulation of glycogen catabolic process);GO:0000164(protein phosphatase type 1 complex);GO:0042587(glycogen granule);GO:0043231(intracellular membrane-bounded organelle);GO:0043231(intracellular membrane-bounded organelle)","04910(Insulin signaling pathway);04931(Insulin resistance);04931(Insulin resistance)","K07189","NA","protein phosphatase 1 regulatory subunit 3B [Source:HGNC Symbol;Acc:HGNC:14942]",{"v":2.98204898026316,"d":"2.98"},{"v":9.76815675588643,"d":"9.77"},{"v":0.305282670496267,"d":"0.31"},{"v":-1.7117823982306,"d":"-1.71"},{"v":0.012236992819127,"d":"0.01"},{"v":0.35612961224921,"d":"0.36"},"down","yes"]
["MSTRG.6801","THRA","ENST00000450525;ENST00000264637;ENST00000577637;ENST00000577486;ENST00000546243;ENST00000584985","GO:0005634(nucleus);GO:0008270(zinc ion binding);GO:0006355(regulation of transcription, DNA-templated);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0043565(sequence-specific DNA binding);GO:0046872(metal ion binding);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0030522(intracellular receptor signaling pathway);GO:0007165(signal transduction);GO:0004887(thyroid hormone receptor activity);GO:0005829(cytosol);GO:0005515(protein binding);GO:0003707(steroid hormone receptor activity);GO:0043401(steroid hormone mediated signaling pathway);GO:0005654(nucleoplasm);GO:0006366(transcription from RNA polymerase II promoter);GO:0019904(protein domain specific binding);GO:0008134(transcription factor binding);GO:0045892(negative regulation of transcription, DNA-templated);GO:0006367(transcription initiation from RNA polymerase II promoter);GO:0044212(transcription regulatory region DNA binding);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0017055(negative regulation of RNA polymerase II transcriptional preinitiation complex assembly);GO:0070324(thyroid hormone binding);GO:0017025(TBP-class protein binding);GO:0009755(hormone-mediated signaling pathway);GO:2000143(negative regulation of DNA-templated transcription, initiation);GO:0000976(transcription regulatory region sequence-specific DNA binding);GO:0002153(steroid receptor RNA activator RNA binding);GO:0003727(single-stranded RNA binding);GO:0004879(RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding);GO:0031490(chromatin DNA binding);GO:0032403(protein complex binding);GO:0001502(cartilage condensation);GO:0001503(ossification);GO:0002155(regulation of thyroid hormone mediated signaling pathway);GO:0007611(learning or memory);GO:0008016(regulation of heart contraction);GO:0008050(female courtship behavior);GO:0009409(response to cold);GO:0009887(animal organ morphogenesis);GO:0010831(positive regulation of myotube differentiation);GO:0030218(erythrocyte differentiation);GO:0030878(thyroid gland development);GO:0033032(regulation of myeloid cell apoptotic process);GO:0042994(cytoplasmic sequestering of transcription factor);GO:0045925(positive regulation of female receptivity);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0050994(regulation of lipid catabolic process);GO:0060509(Type I pneumocyte differentiation);GO:0005737(cytoplasm);GO:0005737(cytoplasm)","04080(Neuroactive ligand-receptor interaction);04919(Thyroid hormone signaling pathway);04919(Thyroid hormone signaling pathway)","K05547","NA","thyroid hormone receptor, alpha [Source:HGNC Symbol;Acc:HGNC:11796]",{"v":3.56880973961776,"d":"3.57"},{"v":1.12796512200029,"d":"1.13"},{"v":3.1639362512282,"d":"3.16"},{"v":1.66172053187029,"d":"1.66"},{"v":0.0123351982626255,"d":"0.01"},{"v":0.35612961224921,"d":"0.36"},"up","yes"]
["MSTRG.5518","MRPS34","ENST00000397375;ENST00000177742;ENST00000569585","GO:0005739(mitochondrion);GO:0003735(structural constituent of ribosome);GO:0032543(mitochondrial translation);GO:0030529(intracellular ribonucleoprotein complex);GO:0005840(ribosome);GO:0005743(mitochondrial inner membrane);GO:0070125(mitochondrial translational elongation);GO:0070126(mitochondrial translational termination);GO:0070126(mitochondrial translational termination)","NA","NA","NA","mitochondrial ribosomal protein S34 [Source:HGNC Symbol;Acc:HGNC:16618]",{"v":3.77879620419325,"d":"3.78"},{"v":12.4592407237922,"d":"12.46"},{"v":0.303292655464731,"d":"0.30"},{"v":-1.72121753280693,"d":"-1.72"},{"v":0.0123625133049827,"d":"0.01"},{"v":0.35612961224921,"d":"0.36"},"down","yes"]
["MSTRG.13531","SKAP2","ENST00000345317;MSTRG.13531.2;ENST00000495802;ENST00000489977;ENST00000490456;ENST00000487720;ENST00000481204;ENST00000468712;ENST00000497511","GO:0005737(cytoplasm);GO:0009967(positive regulation of signal transduction);GO:0005515(protein binding);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0042113(B cell activation);GO:0007165(signal transduction);GO:0006461(protein complex assembly);GO:0005070(SH3/SH2 adaptor activity);GO:0002757(immune response-activating signal transduction);GO:0008285(negative regulation of cell proliferation);GO:0008285(negative regulation of cell proliferation)","NA","NA","NA","src kinase associated phosphoprotein 2 [Source:HGNC Symbol;Acc:HGNC:15687]",{"v":4.67296465231374,"d":"4.67"},{"v":15.2717544155798,"d":"15.27"},{"v":0.30598741474958,"d":"0.31"},{"v":-1.70845577873988,"d":"-1.71"},{"v":0.0123713030357672,"d":"0.01"},{"v":0.35612961224921,"d":"0.36"},"down","yes"]
["MSTRG.246","NIPAL3","ENST00000003912;ENST00000374399;ENST00000432012;ENST00000475663;ENST00000358028;ENST00000488155;ENST00000339255","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005515(protein binding);GO:0015095(magnesium ion transmembrane transporter activity);GO:0015693(magnesium ion transport);GO:1903830(magnesium ion transmembrane transport);GO:1903830(magnesium ion transmembrane transport)","NA","NA","NA","NIPA like domain containing 3 [Source:HGNC Symbol;Acc:HGNC:25233]",{"v":2.12768427392599,"d":"2.13"},{"v":0.669290221820502,"d":"0.67"},{"v":3.17901592546591,"d":"3.18"},{"v":1.66858024375904,"d":"1.67"},{"v":0.0123748834878903,"d":"0.01"},{"v":0.35612961224921,"d":"0.36"},"up","yes"]
["ENSG00000198863","RUNDC1","ENST00000361677;ENST00000590836;ENST00000589705","GO:0005096(GTPase activator activity);GO:0017137(Rab GTPase binding);GO:0006886(intracellular protein transport);GO:0031338(regulation of vesicle fusion);GO:0090630(activation of GTPase activity);GO:0005622(intracellular);GO:0012505(endomembrane system);GO:0012505(endomembrane system)","NA","NA","NA","RUN domain containing 1 [Source:HGNC Symbol;Acc:HGNC:25418]",{"v":0.763010037628758,"d":"0.76"},{"v":2.5172769070843,"d":"2.52"},{"v":0.303109298576347,"d":"0.30"},{"v":-1.72208998409071,"d":"-1.72"},{"v":0.0123932901504278,"d":"0.01"},{"v":0.35612961224921,"d":"0.36"},"down","yes"]
["MSTRG.8970","STARD7-AS1","ENST00000446816;ENST00000432267;ENST00000614453","NA","NA","NA","NA","STARD7 antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:40827]",{"v":0.41163993614304,"d":"0.41"},{"v":1.42746482247765,"d":"1.43"},{"v":0.288371334733529,"d":"0.29"},{"v":-1.79400033285077,"d":"-1.79"},{"v":0.0124278828640336,"d":"0.01"},{"v":0.35612961224921,"d":"0.36"},"down","yes"]
["MSTRG.8292","DBP","ENST00000222122;ENST00000593500;ENST00000601104;ENST00000599385;ENST00000594723","GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0005634(nucleus);GO:0006355(regulation of transcription, DNA-templated);GO:0006366(transcription from RNA polymerase II promoter);GO:0006351(transcription, DNA-templated);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0007623(circadian rhythm);GO:0048511(rhythmic process);GO:0000977(RNA polymerase II regulatory region sequence-specific DNA binding);GO:0007275(multicellular organism development);GO:0001077(transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0001889(liver development);GO:0001889(liver development)","NA","NA","NA","D-box binding PAR bZIP transcription factor [Source:HGNC Symbol;Acc:HGNC:2697]",{"v":1.57682253805012,"d":"1.58"},{"v":0.49413192252445,"d":"0.49"},{"v":3.19109627646471,"d":"3.19"},{"v":1.67405213587604,"d":"1.67"},{"v":0.0124487079636298,"d":"0.01"},{"v":0.35612961224921,"d":"0.36"},"up","yes"]
["MSTRG.2913","ARCN1","ENST00000264028;ENST00000392859;ENST00000359415","GO:0003723(RNA binding);GO:0006810(transport);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0015031(protein transport);GO:0005794(Golgi apparatus);GO:0000139(Golgi membrane);GO:0006890(retrograde vesicle-mediated transport, Golgi to ER);GO:0031410(cytoplasmic vesicle);GO:0016192(vesicle-mediated transport);GO:0030126(COPI vesicle coat);GO:0030663(COPI-coated vesicle membrane);GO:0005789(endoplasmic reticulum membrane);GO:0005829(cytosol);GO:0006886(intracellular protein transport);GO:0006888(ER to Golgi vesicle-mediated transport);GO:0030133(transport vesicle);GO:0008344(adult locomotory behavior);GO:0021691(cerebellar Purkinje cell layer maturation);GO:0043473(pigmentation);GO:0048193(Golgi vesicle transport);GO:0005783(endoplasmic reticulum);GO:0030137(COPI-coated vesicle);GO:0030137(COPI-coated vesicle)","NA","NA","NA","archain 1 [Source:HGNC Symbol;Acc:HGNC:649]",{"v":6.22195408858032,"d":"6.22"},{"v":20.2931297016998,"d":"20.29"},{"v":0.306603967945819,"d":"0.31"},{"v":-1.70555172698815,"d":"-1.71"},{"v":0.0124574441200794,"d":"0.01"},{"v":0.35612961224921,"d":"0.36"},"down","yes"]
["MSTRG.9580","RNF24","ENST00000358395;ENST00000545616;ENST00000336095;ENST00000432261","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005794(Golgi apparatus);GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0005515(protein binding);GO:0000139(Golgi membrane);GO:0061630(ubiquitin protein ligase activity);GO:0043161(proteasome-mediated ubiquitin-dependent protein catabolic process);GO:0042787(protein ubiquitination involved in ubiquitin-dependent protein catabolic process);GO:0000209(protein polyubiquitination);GO:0000209(protein polyubiquitination)","NA","NA","NA","ring finger protein 24 [Source:HGNC Symbol;Acc:HGNC:13779]",{"v":1.21617575743349,"d":"1.22"},{"v":3.97939171622327,"d":"3.98"},{"v":0.305618507591338,"d":"0.31"},{"v":-1.71019618239801,"d":"-1.71"},{"v":0.0124802106269031,"d":"0.01"},{"v":0.35612961224921,"d":"0.36"},"down","yes"]
["MSTRG.12614","MGAT1","ENST00000307826;ENST00000506708;ENST00000427865;ENST00000513431;ENST00000510341;ENST00000514760;ENST00000505682;ENST00000504385;ENST00000504671;ENST00000512695;ENST00000506889;ENST00000514438;ENST00000508702;ENST00000506033;ENST00000502678;ENST00000333055;ENST00000512080;ENST00000506269;ENST00000446023;ENST00000514283;ENST00000508090;ENST00000393340;ENST00000513149","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0046872(metal ion binding);GO:0016740(transferase activity);GO:0016757(transferase activity, transferring glycosyl groups);GO:0006486(protein glycosylation);GO:0005794(Golgi apparatus);GO:0000139(Golgi membrane);GO:0008375(acetylglucosaminyltransferase activity);GO:0070062(extracellular exosome);GO:0005975(carbohydrate metabolic process);GO:1903561(extracellular vesicle);GO:0003827(alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity);GO:0001701(in utero embryonic development);GO:0006049(UDP-N-acetylglucosamine catabolic process);GO:0006049(UDP-N-acetylglucosamine catabolic process)","00510(N-Glycan biosynthesis);00510(N-Glycan biosynthesis)","K00726","EC:2.4.1.101","mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase [Source:HGNC Symbol;Acc:HGNC:7044]",{"v":0.788964667156185,"d":"0.79"},{"v":2.58545268564271,"d":"2.59"},{"v":0.305155329872168,"d":"0.31"},{"v":-1.71238430600647,"d":"-1.71"},{"v":0.0125585337481839,"d":"0.01"},{"v":0.356704794557201,"d":"0.36"},"down","yes"]
["ENSG00000175087","PDIK1L","ENST00000374269;ENST00000444713;ENST00000619836;ENST00000374271","GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0005515(protein binding);GO:0005515(protein binding)","NA","NA","NA","PDLIM1 interacting kinase 1 like [Source:HGNC Symbol;Acc:HGNC:18981]",{"v":0.703662623594267,"d":"0.70"},{"v":0.212981384343991,"d":"0.21"},{"v":3.30386914218646,"d":"3.30"},{"v":1.72415654642524,"d":"1.72"},{"v":0.0125873806451741,"d":"0.01"},{"v":0.356704794557201,"d":"0.36"},"up","yes"]
["MSTRG.8880","C2orf68","ENST00000306336;ENST00000409734;ENST00000423181;ENST00000478626;ENST00000420686","NA","NA","NA","NA","chromosome 2 open reading frame 68 [Source:HGNC Symbol;Acc:HGNC:34353]",{"v":1.65153845433945,"d":"1.65"},{"v":5.41417209630637,"d":"5.41"},{"v":0.305039888825506,"d":"0.31"},{"v":-1.71293018451361,"d":"-1.71"},{"v":0.0126053396920298,"d":"0.01"},{"v":0.356704794557201,"d":"0.36"},"down","yes"]
["ENSG00000115507","OTX1","ENST00000282549;ENST00000476383;ENST00000484066","GO:0005634(nucleus);GO:0006355(regulation of transcription, DNA-templated);GO:0006366(transcription from RNA polymerase II promoter);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0007275(multicellular organism development);GO:0043565(sequence-specific DNA binding);GO:0005515(protein binding);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0001077(transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0009952(anterior/posterior pattern specification);GO:0022037(metencephalon development);GO:0030900(forebrain development);GO:0030901(midbrain development);GO:0042472(inner ear morphogenesis);GO:0048852(diencephalon morphogenesis);GO:0048852(diencephalon morphogenesis)","04550(Signaling pathways regulating pluripotency of stem cells);04550(Signaling pathways regulating pluripotency of stem cells)","K09326","NA","orthodenticle homeobox 1 [Source:HGNC Symbol;Acc:HGNC:8521]",{"v":0.261333032071177,"d":"0.26"},{"v":0.893297968342644,"d":"0.89"},{"v":0.29254855751663,"d":"0.29"},{"v":-1.77325199027909,"d":"-1.77"},{"v":0.0126188542170211,"d":"0.01"},{"v":0.356704794557201,"d":"0.36"},"down","yes"]
["ENSG00000163596","ICA1L","ENST00000617388;ENST00000494560;ENST00000438804;ENST00000358299;ENST00000425178;ENST00000441547;ENST00000412210;ENST00000435143;ENST00000392237","GO:0019904(protein domain specific binding);GO:0005515(protein binding);GO:0007286(spermatid development);GO:0001669(acrosomal vesicle);GO:0001669(acrosomal vesicle)","NA","NA","NA","islet cell autoantigen 1 like [Source:HGNC Symbol;Acc:HGNC:14442]",{"v":0.253213711454992,"d":"0.25"},{"v":0.076104129364031,"d":"0.08"},{"v":3.32720068636207,"d":"3.33"},{"v":1.73430888770783,"d":"1.73"},{"v":0.012747423409957,"d":"0.01"},{"v":0.357719026230008,"d":"0.36"},"up","yes"]
["MSTRG.8408","TSEN34","ENST00000396388;ENST00000396383;ENST00000455798;ENST00000456872;ENST00000302937;ENST00000496583;ENST00000429671","GO:0005634(nucleus);GO:0000213(tRNA-intron endonuclease activity);GO:0090501(RNA phosphodiester bond hydrolysis);GO:0090502(RNA phosphodiester bond hydrolysis, endonucleolytic);GO:0000214(tRNA-intron endonuclease complex);GO:0000379(tRNA-type intron splice site recognition and cleavage);GO:0006388(tRNA splicing, via endonucleolytic cleavage and ligation);GO:0006397(mRNA processing);GO:0008033(tRNA processing);GO:0016829(lyase activity);GO:0090305(nucleic acid phosphodiester bond hydrolysis);GO:0004519(endonuclease activity);GO:0005730(nucleolus);GO:0005654(nucleoplasm);GO:0005654(nucleoplasm)","NA","NA","NA","tRNA splicing endonuclease subunit 34 [Source:HGNC Symbol;Acc:HGNC:15506]",{"v":3.19685231846414,"d":"3.20"},{"v":10.4157294511575,"d":"10.42"},{"v":0.306925437479453,"d":"0.31"},{"v":-1.70403987591691,"d":"-1.70"},{"v":0.0127706622285283,"d":"0.01"},{"v":0.357719026230008,"d":"0.36"},"down","yes"]
["ENSG00000251192","ZNF674","ENST00000453909;ENST00000414387;ENST00000518795;ENST00000521626;ENST00000522017;ENST00000523374","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0005622(intracellular);GO:0005622(intracellular)","NA","NA","NA","zinc finger protein 674 [Source:HGNC Symbol;Acc:HGNC:17625]",{"v":0.470177814122199,"d":"0.47"},{"v":0.140466008705465,"d":"0.14"},{"v":3.34727111886611,"d":"3.35"},{"v":1.74298540970462,"d":"1.74"},{"v":0.0127799643631991,"d":"0.01"},{"v":0.357719026230008,"d":"0.36"},"up","yes"]
["ENSG00000166526","ZNF3","ENST00000428683;ENST00000292393;ENST00000479192;ENST00000413658;ENST00000299667;ENST00000412947;ENST00000487620;ENST00000303915;ENST00000449785;ENST00000415068;ENST00000424697","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0005622(intracellular);GO:0008270(zinc ion binding);GO:0005515(protein binding);GO:0007275(multicellular organism development);GO:0030154(cell differentiation);GO:0042802(identical protein binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0045321(leukocyte activation);GO:0045321(leukocyte activation)","NA","NA","NA","zinc finger protein 3 [Source:HGNC Symbol;Acc:HGNC:13089]",{"v":1.09432467772861,"d":"1.09"},{"v":0.339341832042773,"d":"0.34"},{"v":3.22484460916883,"d":"3.22"},{"v":1.68922964519245,"d":"1.69"},{"v":0.012863942377036,"d":"0.01"},{"v":0.357719026230008,"d":"0.36"},"up","yes"]
["MSTRG.3166","KLRD1","ENST00000381908;ENST00000336164;ENST00000540271;ENST00000344825;ENST00000350274;ENST00000539374;ENST00000538997;ENST00000543420;ENST00000539792","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0030246(carbohydrate binding);GO:0005515(protein binding);GO:0050776(regulation of immune response);GO:0005886(plasma membrane);GO:0045087(innate immune response);GO:0043235(receptor complex);GO:0007166(cell surface receptor signaling pathway);GO:0004888(transmembrane signaling receptor activity);GO:0023024(MHC class I protein complex binding);GO:1990405(protein antigen binding);GO:0002228(natural killer cell mediated immunity);GO:0023030(MHC class Ib protein binding, via antigen binding groove);GO:0009897(external side of plasma membrane);GO:0009897(external side of plasma membrane)","04650(Natural killer cell mediated cytotoxicity);04612(Antigen processing and presentation);05332(Graft-versus-host disease);05332(Graft-versus-host disease)","K06516","NA","killer cell lectin like receptor D1 [Source:HGNC Symbol;Acc:HGNC:6378]",{"v":1.71098678165939,"d":"1.71"},{"v":0.545196320501034,"d":"0.55"},{"v":3.13829480743193,"d":"3.14"},{"v":1.64998088361339,"d":"1.65"},{"v":0.0128953866356625,"d":"0.01"},{"v":0.357719026230008,"d":"0.36"},"up","yes"]
["ENSG00000185163","DDX51","ENST00000397333;ENST00000462829;ENST00000545991;ENST00000541489;ENST00000329073","GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0005634(nucleus);GO:0016020(membrane);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0016787(hydrolase activity);GO:0004386(helicase activity);GO:0042254(ribosome biogenesis);GO:0005730(nucleolus);GO:0006364(rRNA processing);GO:0005737(cytoplasm);GO:0004004(ATP-dependent RNA helicase activity);GO:0010501(RNA secondary structure unwinding);GO:0010501(RNA secondary structure unwinding)","NA","NA","NA","DEAD-box helicase 51 [Source:HGNC Symbol;Acc:HGNC:20082]",{"v":1.49227316637863,"d":"1.49"},{"v":0.46980895930872,"d":"0.47"},{"v":3.1763403758293,"d":"3.18"},{"v":1.66736551959963,"d":"1.67"},{"v":0.0129125673481202,"d":"0.01"},{"v":0.357719026230008,"d":"0.36"},"up","yes"]
["MSTRG.10336","TTC28","ENST00000397906;ENST00000490475;ENST00000442232;ENST00000612946","GO:0005737(cytoplasm);GO:0051301(cell division);GO:0005856(cytoskeleton);GO:0007049(cell cycle);GO:0007346(regulation of mitotic cell cycle);GO:0000922(spindle pole);GO:0005815(microtubule organizing center);GO:0005819(spindle);GO:0030496(midbody);GO:0005813(centrosome);GO:0005813(centrosome)","NA","NA","NA","tetratricopeptide repeat domain 28 [Source:HGNC Symbol;Acc:HGNC:29179]",{"v":0.361312238038751,"d":"0.36"},{"v":0.110449852827204,"d":"0.11"},{"v":3.27127858290599,"d":"3.27"},{"v":1.70985462492454,"d":"1.71"},{"v":0.0129428995281585,"d":"0.01"},{"v":0.357719026230008,"d":"0.36"},"up","yes"]
["MSTRG.7147","AC005332.8","ENST00000622750","NA","NA","NA","NA",null,{"v":1.429672,"d":"1.43"},{"v":0.441281,"d":"0.44"},{"v":3.2398222447828,"d":"3.24"},{"v":1.69591466076259,"d":"1.70"},{"v":0.0129479729762765,"d":"0.01"},{"v":0.357719026230008,"d":"0.36"},"up","yes"]
["ENSG00000176542","USF3","ENST00000316407;ENST00000496826;ENST00000478658","GO:0046983(protein dimerization activity);GO:0005634(nucleus);GO:0003677(DNA binding);GO:0005783(endoplasmic reticulum);GO:0000139(Golgi membrane);GO:0004571(mannosyl-oligosaccharide 1,2-alpha-mannosidase activity);GO:0006491(N-glycan processing);GO:0006491(N-glycan processing)","NA","NA","NA","upstream transcription factor family member 3 [Source:HGNC Symbol;Acc:HGNC:30494]",{"v":2.87260530703159,"d":"2.87"},{"v":0.917153301645072,"d":"0.92"},{"v":3.13208849805052,"d":"3.13"},{"v":1.64712497696319,"d":"1.65"},{"v":0.0129560592454748,"d":"0.01"},{"v":0.357719026230008,"d":"0.36"},"up","yes"]
["MSTRG.14792","TMEM252","ENST00000377311","GO:0016020(membrane);GO:0016021(integral component of membrane)","NA","NA","NA","transmembrane protein 252 [Source:HGNC Symbol;Acc:HGNC:28537]",{"v":0.510294,"d":"0.51"},{"v":1.7973,"d":"1.80"},{"v":0.283922550492405,"d":"0.28"},{"v":-1.81643065550612,"d":"-1.82"},{"v":0.0129756970433101,"d":"0.01"},{"v":0.357719026230008,"d":"0.36"},"down","yes"]
["ENSG00000162601","MYSM1","ENST00000472487;ENST00000493821;ENST00000481973;ENST00000401044;ENST00000483003;ENST00000622766;ENST00000489282","GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0005654(nucleoplasm);GO:0004843(thiol-dependent ubiquitin-specific protease activity);GO:0016787(hydrolase activity);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0016569(covalent chromatin modification);GO:0003677(DNA binding);GO:0005886(plasma membrane);GO:0008233(peptidase activity);GO:0006508(proteolysis);GO:0036459(thiol-dependent ubiquitinyl hydrolase activity);GO:0008237(metallopeptidase activity);GO:0003713(transcription coactivator activity);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0016579(protein deubiquitination);GO:0042393(histone binding);GO:0006338(chromatin remodeling);GO:0032403(protein complex binding);GO:0030334(regulation of cell migration);GO:0035522(monoubiquitinated histone H2A deubiquitination);GO:0043473(pigmentation);GO:0051797(regulation of hair follicle development);GO:0051797(regulation of hair follicle development)","NA","NA","NA","Myb like, SWIRM and MPN domains 1 [Source:HGNC Symbol;Acc:HGNC:29401]",{"v":0.631459642313717,"d":"0.63"},{"v":2.06281922868651,"d":"2.06"},{"v":0.306114871110541,"d":"0.31"},{"v":-1.70785496195878,"d":"-1.71"},{"v":0.0130008601454776,"d":"0.01"},{"v":0.357719026230008,"d":"0.36"},"down","yes"]
["MSTRG.1369","TRAF5","ENST00000261464;ENST00000473385;ENST00000494355;ENST00000488428;ENST00000462410","GO:0051091(positive regulation of sequence-specific DNA binding transcription factor activity);GO:0005737(cytoplasm);GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0005829(cytosol);GO:0007165(signal transduction);GO:0042981(regulation of apoptotic process);GO:0005515(protein binding);GO:0006915(apoptotic process);GO:0043123(positive regulation of I-kappaB kinase/NF-kappaB signaling);GO:0005813(centrosome);GO:0042802(identical protein binding);GO:0031625(ubiquitin protein ligase binding);GO:0051092(positive regulation of NF-kappaB transcription factor activity);GO:0031996(thioesterase binding);GO:0009898(cytoplasmic side of plasma membrane);GO:0035631(CD40 receptor complex);GO:0035631(CD40 receptor complex)","04064(NF-kappa B signaling pathway);04668(TNF signaling pathway);04217(Necroptosis);04621(NOD-like receptor signaling pathway);04657(IL-17 signaling pathway);05200(Pathways in cancer);05203(Viral carcinogenesis);05222(Small cell lung cancer);05168(Herpes simplex infection);05169(Epstein-Barr virus infection);05169(Epstein-Barr virus infection)","K09849","NA","TNF receptor associated factor 5 [Source:HGNC Symbol;Acc:HGNC:12035]",{"v":1.89131806384394,"d":"1.89"},{"v":0.600507762358679,"d":"0.60"},{"v":3.14953141723798,"d":"3.15"},{"v":1.65513720248135,"d":"1.66"},{"v":0.0130112052390586,"d":"0.01"},{"v":0.357719026230008,"d":"0.36"},"up","yes"]
["MSTRG.7455","DSC2","ENST00000280904;ENST00000251081","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0046872(metal ion binding);GO:0005509(calcium ion binding);GO:0007155(cell adhesion);GO:0007156(homophilic cell adhesion via plasma membrane adhesion molecules);GO:0005886(plasma membrane);GO:0030054(cell junction);GO:0031410(cytoplasmic vesicle);GO:0005515(protein binding);GO:0070062(extracellular exosome);GO:0031424(keratinization);GO:0014704(intercalated disc);GO:0086091(regulation of heart rate by cardiac conduction);GO:0070268(cornification);GO:0001533(cornified envelope);GO:0030057(desmosome);GO:0086083(cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication);GO:0086073(bundle of His cell-Purkinje myocyte adhesion involved in cell communication);GO:0098911(regulation of ventricular cardiac muscle cell action potential);GO:0009267(cellular response to starvation);GO:0086042(cardiac muscle cell-cardiac muscle cell adhesion);GO:0005913(cell-cell adherens junction);GO:0005913(cell-cell adherens junction)","05412(Arrhythmogenic right ventricular cardiomyopathy (ARVC));05412(Arrhythmogenic right ventricular cardiomyopathy (ARVC))","K07601","NA","desmocollin 2 [Source:HGNC Symbol;Acc:HGNC:3036]",{"v":0.885868715140247,"d":"0.89"},{"v":2.86520739932099,"d":"2.87"},{"v":0.309181358162828,"d":"0.31"},{"v":-1.69347475912013,"d":"-1.69"},{"v":0.0131889514943238,"d":"0.01"},{"v":0.36177984941833,"d":"0.36"},"down","yes"]
["MSTRG.3965","KBTBD6","ENST00000379485","GO:0016567(protein ubiquitination);GO:0005515(protein binding);GO:0004842(ubiquitin-protein transferase activity);GO:0003674(molecular_function);GO:0008150(biological_process);GO:0005575(cellular_component);GO:0005829(cytosol);GO:0043687(post-translational protein modification);GO:0031463(Cul3-RING ubiquitin ligase complex)","NA","NA","NA","kelch repeat and BTB domain containing 6 [Source:HGNC Symbol;Acc:HGNC:25340]",{"v":1.089684,"d":"1.09"},{"v":0.341533,"d":"0.34"},{"v":3.19056723654815,"d":"3.19"},{"v":1.67381293703259,"d":"1.67"},{"v":0.0132695559498105,"d":"0.01"},{"v":0.363163619880951,"d":"0.36"},"up","yes"]
["MSTRG.194","PADI2","ENST00000466151;ENST00000375486;ENST00000375481;ENST00000479534","GO:0005737(cytoplasm);GO:0016787(hydrolase activity);GO:0005509(calcium ion binding);GO:0004668(protein-arginine deiminase activity);GO:0018101(protein citrullination);GO:1990830(cellular response to leukemia inhibitory factor);GO:0005576(extracellular region);GO:0005634(nucleus);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0030331(estrogen receptor binding);GO:0043312(neutrophil degranulation);GO:0021762(substantia nigra development);GO:0035578(azurophil granule lumen);GO:0030520(intracellular estrogen receptor signaling pathway);GO:0048096(chromatin-mediated maintenance of transcription);GO:0035327(transcriptionally active chromatin);GO:0006325(chromatin organization);GO:0036413(histone H3-R26 citrullination);GO:0010848(regulation of chromatin disassembly);GO:0070100(negative regulation of chemokine-mediated signaling pathway);GO:1901624(negative regulation of lymphocyte chemotaxis);GO:1901624(negative regulation of lymphocyte chemotaxis)","NA","NA","NA","peptidyl arginine deiminase 2 [Source:HGNC Symbol;Acc:HGNC:18341]",{"v":4.03589792362968,"d":"4.04"},{"v":13.009297699365,"d":"13.01"},{"v":0.31023180627396,"d":"0.31"},{"v":-1.68858148974682,"d":"-1.69"},{"v":0.0133288210124109,"d":"0.01"},{"v":0.363958418665424,"d":"0.36"},"down","yes"]
["ENSG00000261455","LINC01003","ENST00000564834","NA","NA","NA","NA","long intergenic non-protein coding RNA 1003 [Source:HGNC Symbol;Acc:HGNC:48957]",{"v":0.537721,"d":"0.54"},{"v":1.809867,"d":"1.81"},{"v":0.297105256905618,"d":"0.30"},{"v":-1.75095396280535,"d":"-1.75"},{"v":0.0133693277943587,"d":"0.01"},{"v":0.364238564026398,"d":"0.36"},"down","yes"]
["MSTRG.3623","HAL","ENST00000261208;ENST00000544080;ENST00000552509;ENST00000548636;ENST00000549376;ENST00000538703;ENST00000548808;ENST00000551562;ENST00000546579;ENST00000541929","GO:0005737(cytoplasm);GO:0003824(catalytic activity);GO:0016829(lyase activity);GO:0005829(cytosol);GO:0006548(histidine catabolic process);GO:0016841(ammonia-lyase activity);GO:0006547(histidine metabolic process);GO:0019556(histidine catabolic process to glutamate and formamide);GO:0019557(histidine catabolic process to glutamate and formate);GO:0004397(histidine ammonia-lyase activity);GO:0004397(histidine ammonia-lyase activity)","00340(Histidine metabolism);00340(Histidine metabolism)","K01745","EC:4.3.1.3","histidine ammonia-lyase [Source:HGNC Symbol;Acc:HGNC:4806]",{"v":2.47564709211038,"d":"2.48"},{"v":8.00050562223086,"d":"8.00"},{"v":0.309436329277908,"d":"0.31"},{"v":-1.69228550898521,"d":"-1.69"},{"v":0.0134303735426643,"d":"0.01"},{"v":0.364789074299953,"d":"0.36"},"down","yes"]
["MSTRG.5996","CKLF;CMTM1;CKLF-CMTM1","ENST00000264001;ENST00000351137;ENST00000479381;ENST00000457188;ENST00000527845;ENST00000529386;ENST00000533953;ENST00000528484;ENST00000379500;ENST00000527729;ENST00000417030;ENST00000526149;ENST00000533915;ENST00000328020;ENST00000616804;ENST00000362093;ENST00000534692;ENST00000532838;ENST00000345436;ENST00000563092","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005576(extracellular region);GO:0005125(cytokine activity);GO:0005615(extracellular space);GO:0006935(chemotaxis);GO:0030593(neutrophil chemotaxis);GO:0008283(cell proliferation);GO:0008009(chemokine activity);GO:0048246(macrophage chemotaxis);GO:0048247(lymphocyte chemotaxis);GO:0032940(secretion by cell);GO:0030595(leukocyte chemotaxis);GO:0030595(leukocyte chemotaxis)","NA","NA","NA","chemokine like factor [Source:HGNC Symbol;Acc:HGNC:13253];CKLF like MARVEL transmembrane domain containing 1 [Source:HGNC Symbol;Acc:HGNC:19172];CKLF-CMTM1 readthrough [Source:HGNC Symbol;Acc:HGNC:39977]",{"v":2.50161617925551,"d":"2.50"},{"v":8.15643302312974,"d":"8.16"},{"v":0.306704679871889,"d":"0.31"},{"v":-1.70507791466503,"d":"-1.71"},{"v":0.0134501203279504,"d":"0.01"},{"v":0.364789074299953,"d":"0.36"},"down","yes"]
["ENSG00000204936","CD177","ENST00000618265;ENST00000378012","GO:0016020(membrane);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0031225(anchored component of membrane);GO:0050900(leukocyte migration);GO:0070062(extracellular exosome);GO:0043312(neutrophil degranulation);GO:0035579(specific granule membrane);GO:0070821(tertiary granule membrane);GO:0007596(blood coagulation);GO:0007596(blood coagulation)","NA","NA","NA","CD177 molecule [Source:HGNC Symbol;Acc:HGNC:30072]",{"v":1.38044656857257,"d":"1.38"},{"v":4.50510544422231,"d":"4.51"},{"v":0.306418259386794,"d":"0.31"},{"v":-1.70642582522931,"d":"-1.71"},{"v":0.0135268882468575,"d":"0.01"},{"v":0.365454086762591,"d":"0.37"},"down","yes"]
["MSTRG.220","ALPL","ENST00000374840;ENST00000540617;ENST00000374829;ENST00000468526;ENST00000374832;ENST00000374830","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0046872(metal ion binding);GO:0016787(hydrolase activity);GO:0003824(catalytic activity);GO:0008152(metabolic process);GO:0016791(phosphatase activity);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0004035(alkaline phosphatase activity);GO:0031225(anchored component of membrane);GO:0016462(pyrophosphatase activity);GO:0001958(endochondral ossification);GO:0003006(developmental process involved in reproduction);GO:0016311(dephosphorylation);GO:0032496(response to lipopolysaccharide);GO:0046677(response to antibiotic);GO:0051384(response to glucocorticoid);GO:0071407(cellular response to organic cyclic compound);GO:0071529(cementum mineralization);GO:0005578(proteinaceous extracellular matrix);GO:0005615(extracellular space);GO:0065010(extracellular membrane-bounded organelle);GO:0005576(extracellular region);GO:0070062(extracellular exosome);GO:0031214(biomineral tissue development);GO:0006501(C-terminal protein lipidation);GO:0001501(skeletal system development);GO:0033280(response to vitamin D);GO:0001649(osteoblast differentiation);GO:0001649(osteoblast differentiation)","00730(Thiamine metabolism);00790(Folate biosynthesis);00790(Folate biosynthesis)","K01077","EC:3.1.3.1","alkaline phosphatase, liver/bone/kidney [Source:HGNC Symbol;Acc:HGNC:438]",{"v":22.7461312670436,"d":"22.75"},{"v":72.9861565673429,"d":"72.99"},{"v":0.311649939342349,"d":"0.31"},{"v":-1.68200166293594,"d":"-1.68"},{"v":0.0135746240489786,"d":"0.01"},{"v":0.365454086762591,"d":"0.37"},"down","yes"]
["MSTRG.1889","FRAT1","ENST00000371021","GO:0005737(cytoplasm);GO:0043231(intracellular membrane-bounded organelle);GO:0005829(cytosol);GO:0005515(protein binding);GO:0016055(Wnt signaling pathway);GO:1904886(beta-catenin destruction complex disassembly)","04310(Wnt signaling pathway);05200(Pathways in cancer);05225(Hepatocellular carcinoma);05226(Gastric cancer);05224(Breast cancer)","K03069","NA","FRAT1, WNT signaling pathway regulator [Source:HGNC Symbol;Acc:HGNC:3944]",{"v":10.611184,"d":"10.61"},{"v":34.074562,"d":"34.07"},{"v":0.311410723342533,"d":"0.31"},{"v":-1.68310947080847,"d":"-1.68"},{"v":0.0135849096309742,"d":"0.01"},{"v":0.365454086762591,"d":"0.37"},"down","yes"]
["MSTRG.10458","JOSD1","ENST00000216039;ENST00000493939;ENST00000412832;ENST00000482442;ENST00000427389;ENST00000490169;ENST00000417712;ENST00000462610","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0004843(thiol-dependent ubiquitin-specific protease activity);GO:0016579(protein deubiquitination);GO:0016787(hydrolase activity);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0008233(peptidase activity);GO:0006508(proteolysis);GO:0036459(thiol-dependent ubiquitinyl hydrolase activity);GO:0005829(cytosol);GO:0005829(cytosol)","NA","NA","NA","Josephin domain containing 1 [Source:HGNC Symbol;Acc:HGNC:28953]",{"v":1.85599726329172,"d":"1.86"},{"v":6.00287188511327,"d":"6.00"},{"v":0.309184886636423,"d":"0.31"},{"v":-1.69345829473061,"d":"-1.69"},{"v":0.0136114211250431,"d":"0.01"},{"v":0.365454086762591,"d":"0.37"},"down","yes"]
["MSTRG.9122","MGAT5","ENST00000481801;MSTRG.9122.4;ENST00000281923;ENST00000468758;ENST00000409645;ENST00000488365","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016740(transferase activity);GO:0016757(transferase activity, transferring glycosyl groups);GO:0005794(Golgi apparatus);GO:0000139(Golgi membrane);GO:0006487(protein N-linked glycosylation);GO:0006486(protein glycosylation);GO:0030144(alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity);GO:0070062(extracellular exosome);GO:0008375(acetylglucosaminyltransferase activity);GO:0008375(acetylglucosaminyltransferase activity)","00510(N-Glycan biosynthesis);00510(N-Glycan biosynthesis)","K00744","EC:2.4.1.155","mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase [Source:HGNC Symbol;Acc:HGNC:7049]",{"v":2.12060320937281,"d":"2.12"},{"v":6.81552316880392,"d":"6.82"},{"v":0.311143129712955,"d":"0.31"},{"v":-1.68434970416096,"d":"-1.68"},{"v":0.0136263814114269,"d":"0.01"},{"v":0.365454086762591,"d":"0.37"},"down","yes"]
["ENSG00000141854","MISP3","ENST00000587086;ENST00000269720;ENST00000590772;ENST00000591982","NA","NA","NA","NA","MISP family member 3 [Source:HGNC Symbol;Acc:HGNC:26963]",{"v":1.24489623279524,"d":"1.24"},{"v":0.376322667374681,"d":"0.38"},{"v":3.30805540224282,"d":"3.31"},{"v":1.72598339650183,"d":"1.73"},{"v":0.0137442406821379,"d":"0.01"},{"v":0.367795880654009,"d":"0.37"},"up","yes"]
["MSTRG.132","RBP7","ENST00000294435;ENST00000315901","GO:0006810(transport);GO:0005215(transporter activity);GO:0008289(lipid binding);GO:0005737(cytoplasm);GO:0005515(protein binding);GO:0016918(retinal binding);GO:0019841(retinol binding);GO:0005501(retinoid binding);GO:0005501(retinoid binding)","NA","NA","NA","retinol binding protein 7 [Source:HGNC Symbol;Acc:HGNC:30316]",{"v":5.72280867944251,"d":"5.72"},{"v":18.4697087421603,"d":"18.47"},{"v":0.309848344623822,"d":"0.31"},{"v":-1.69036583420857,"d":"-1.69"},{"v":0.0137812570894514,"d":"0.01"},{"v":0.367968731421672,"d":"0.37"},"down","yes"]
["ENSG00000144647","POMGNT2","ENST00000344697;ENST00000441964","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016740(transferase activity);GO:0016757(transferase activity, transferring glycosyl groups);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005515(protein binding);GO:0006486(protein glycosylation);GO:0035269(protein O-linked mannosylation);GO:0097363(protein O-GlcNAc transferase activity);GO:0006493(protein O-linked glycosylation);GO:0001764(neuron migration);GO:0008375(acetylglucosaminyltransferase activity);GO:0008375(acetylglucosaminyltransferase activity)","00515(Mannose type O-glycan biosyntheis);00515(Mannose type O-glycan biosyntheis)","K18207","EC:2.4.1.312","protein O-linked mannose N-acetylglucosaminyltransferase 2 (beta 1,4-) [Source:HGNC Symbol;Acc:HGNC:25902]",{"v":2.3422474137931,"d":"2.34"},{"v":0.738925874812594,"d":"0.74"},{"v":3.16980023792933,"d":"3.17"},{"v":1.66439192401464,"d":"1.66"},{"v":0.0138184200391089,"d":"0.01"},{"v":0.3681447214844,"d":"0.37"},"up","yes"]
["MSTRG.6115","HP","ENST00000355906;ENST00000566821;ENST00000357763;ENST00000570083;ENST00000561927;ENST00000565807;ENST00000398131;ENST00000565574","GO:0010942(positive regulation of cell death);GO:0005576(extracellular region);GO:0005515(protein binding);GO:0005615(extracellular space);GO:0098869(cellular oxidant detoxification);GO:0002376(immune system process);GO:0006898(receptor-mediated endocytosis);GO:0042742(defense response to bacterium);GO:0030492(hemoglobin binding);GO:0070062(extracellular exosome);GO:0072562(blood microparticle);GO:0043312(neutrophil degranulation);GO:0006953(acute-phase response);GO:0035580(specific granule lumen);GO:1904724(tertiary granule lumen);GO:0006952(defense response);GO:0016209(antioxidant activity);GO:0042542(response to hydrogen peroxide);GO:0051354(negative regulation of oxidoreductase activity);GO:2000296(negative regulation of hydrogen peroxide catabolic process);GO:0031838(haptoglobin-hemoglobin complex);GO:0071682(endocytic vesicle lumen);GO:0006508(proteolysis);GO:0004252(serine-type endopeptidase activity);GO:0004252(serine-type endopeptidase activity)","NA","NA","NA","haptoglobin [Source:HGNC Symbol;Acc:HGNC:5141]",{"v":0.257279496207216,"d":"0.26"},{"v":0.852632662349676,"d":"0.85"},{"v":0.301747173862901,"d":"0.30"},{"v":-1.72858783599678,"d":"-1.73"},{"v":0.0139759669905539,"d":"0.01"},{"v":0.369749839401294,"d":"0.37"},"down","yes"]
["ENSG00000148331","ASB6","ENST00000277458;ENST00000277459","GO:0005737(cytoplasm);GO:0016567(protein ubiquitination);GO:0035556(intracellular signal transduction);GO:0005515(protein binding);GO:0005829(cytosol);GO:0043687(post-translational protein modification);GO:0005622(intracellular);GO:0005622(intracellular)","NA","NA","NA","ankyrin repeat and SOCS box containing 6 [Source:HGNC Symbol;Acc:HGNC:17181]",{"v":2.47062082431848,"d":"2.47"},{"v":0.791206901774124,"d":"0.79"},{"v":3.12259766538766,"d":"3.12"},{"v":1.64274669566572,"d":"1.64"},{"v":0.0139898555336872,"d":"0.01"},{"v":0.369749839401294,"d":"0.37"},"up","yes"]
["MSTRG.7729","RFX2","ENST00000303657;ENST00000589340;ENST00000592546;ENST00000588021;ENST00000590822;ENST00000587181;ENST00000589742;ENST00000593241;ENST00000590778;ENST00000359161;ENST00000592337;ENST00000586806;ENST00000586940;ENST00000587700","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0005515(protein binding);GO:0030154(cell differentiation);GO:0007283(spermatogenesis);GO:0060271(cilium assembly);GO:0030030(cell projection organization);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:0007286(spermatid development);GO:0000977(RNA polymerase II regulatory region sequence-specific DNA binding);GO:0001675(acrosome assembly);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:1990830(cellular response to leukemia inhibitory factor);GO:1990830(cellular response to leukemia inhibitory factor)","NA","NA","NA","regulatory factor X2 [Source:HGNC Symbol;Acc:HGNC:9983]",{"v":0.554731140092369,"d":"0.55"},{"v":1.78802503749725,"d":"1.79"},{"v":0.310247971062442,"d":"0.31"},{"v":-1.68850631933503,"d":"-1.69"},{"v":0.0139981703592009,"d":"0.01"},{"v":0.369749839401294,"d":"0.37"},"down","yes"]
["ENSG00000131323","TRAF3","ENST00000560371;ENST00000558700;ENST00000392745;ENST00000347662;ENST00000351691","GO:0005737(cytoplasm);GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0016740(transferase activity);GO:0007165(signal transduction);GO:0042981(regulation of apoptotic process);GO:0016567(protein ubiquitination);GO:0005739(mitochondrion);GO:0005515(protein binding);GO:0006915(apoptotic process);GO:0008063(Toll signaling pathway);GO:0033209(tumor necrosis factor-mediated signaling pathway);GO:0002376(immune system process);GO:0045087(innate immune response);GO:0005768(endosome);GO:0005829(cytosol);GO:0030162(regulation of proteolysis);GO:0016579(protein deubiquitination);GO:0001817(regulation of cytokine production);GO:0032088(negative regulation of NF-kappaB transcription factor activity);GO:0050688(regulation of defense response to virus);GO:0031625(ubiquitin protein ligase binding);GO:0004871(signal transducer activity);GO:0019903(protein phosphatase binding);GO:0035666(TRIF-dependent toll-like receptor signaling pathway);GO:0031996(thioesterase binding);GO:0009898(cytoplasmic side of plasma membrane);GO:0035631(CD40 receptor complex);GO:0005164(tumor necrosis factor receptor binding);GO:0032480(negative regulation of type I interferon production);GO:0004842(ubiquitin-protein transferase activity);GO:0002224(toll-like receptor signaling pathway);GO:0019901(protein kinase binding);GO:0032648(regulation of interferon-beta production);GO:0032648(regulation of interferon-beta production)","04064(NF-kappa B signaling pathway);04668(TNF signaling pathway);04620(Toll-like receptor signaling pathway);04621(NOD-like receptor signaling pathway);04622(RIG-I-like receptor signaling pathway);04657(IL-17 signaling pathway);05200(Pathways in cancer);05203(Viral carcinogenesis);05222(Small cell lung cancer);05160(Hepatitis C);05168(Herpes simplex infection);05167(Kaposi's sarcoma-associated herpesvirus infection);05169(Epstein-Barr virus infection);05165(Human papillomavirus infection);05165(Human papillomavirus infection)","K03174","NA","TNF receptor associated factor 3 [Source:HGNC Symbol;Acc:HGNC:12033]",{"v":1.73550582282464,"d":"1.74"},{"v":0.55681228536851,"d":"0.56"},{"v":3.11685978996682,"d":"3.12"},{"v":1.64009325766806,"d":"1.64"},{"v":0.014005558067027,"d":"0.01"},{"v":0.369749839401294,"d":"0.37"},"up","yes"]
["MSTRG.6604","CPD","ENST00000225719;ENST00000584221;ENST00000581826;ENST00000588977;ENST00000580396;ENST00000583275;ENST00000584050;ENST00000584051","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0016787(hydrolase activity);GO:0005886(plasma membrane);GO:0008233(peptidase activity);GO:0006508(proteolysis);GO:0004181(metallocarboxypeptidase activity);GO:0004180(carboxypeptidase activity);GO:0008237(metallopeptidase activity);GO:0005615(extracellular space);GO:0070062(extracellular exosome);GO:0016485(protein processing);GO:0004185(serine-type carboxypeptidase activity);GO:0006518(peptide metabolic process);GO:0006518(peptide metabolic process)","NA","NA","NA","carboxypeptidase D [Source:HGNC Symbol;Acc:HGNC:2301]",{"v":4.79457289060006,"d":"4.79"},{"v":15.3004295051867,"d":"15.30"},{"v":0.313361980392429,"d":"0.31"},{"v":-1.67409794387913,"d":"-1.67"},{"v":0.0140321937058953,"d":"0.01"},{"v":0.369749839401294,"d":"0.37"},"down","yes"]
["MSTRG.10696","RN7SL4P","ENST00000584058","NA","NA","NA","NA","RNA, 7SL, cytoplasmic 4, pseudogene [Source:HGNC Symbol;Acc:HGNC:10039]",{"v":227.054962,"d":"227.05"},{"v":73.785805,"d":"73.79"},{"v":3.07721738618966,"d":"3.08"},{"v":1.62162636466587,"d":"1.62"},{"v":0.0140909681895306,"d":"0.01"},{"v":0.370487857943946,"d":"0.37"},"up","yes"]
["MSTRG.8673","MCFD2","ENST00000319466;ENST00000409207;ENST00000444761;ENST00000409147;ENST00000434262;ENST00000477791;ENST00000409913;ENST00000417180;ENST00000479225;ENST00000409105;ENST00000409800;ENST00000409218;ENST00000487121;ENST00000409973;ENST00000470873","GO:0006810(transport);GO:0015031(protein transport);GO:0046872(metal ion binding);GO:0005509(calcium ion binding);GO:0005794(Golgi apparatus);GO:0005783(endoplasmic reticulum);GO:0016192(vesicle-mediated transport);GO:0000139(Golgi membrane);GO:0005789(endoplasmic reticulum membrane);GO:0006888(ER to Golgi vesicle-mediated transport);GO:0048208(COPII vesicle coating);GO:0012507(ER to Golgi transport vesicle membrane);GO:0033116(endoplasmic reticulum-Golgi intermediate compartment membrane);GO:0005793(endoplasmic reticulum-Golgi intermediate compartment);GO:0018279(protein N-linked glycosylation via asparagine);GO:0018279(protein N-linked glycosylation via asparagine)","NA","NA","NA","multiple coagulation factor deficiency 2 [Source:HGNC Symbol;Acc:HGNC:18451]",{"v":3.80182866316316,"d":"3.80"},{"v":1.22520393009676,"d":"1.23"},{"v":3.10301703232613,"d":"3.10"},{"v":1.63367161577898,"d":"1.63"},{"v":0.0142060561342648,"d":"0.01"},{"v":0.372317060983366,"d":"0.37"},"up","yes"]
["MSTRG.5876","ZNF668","ENST00000300849;ENST00000539836;ENST00000538906;ENST00000414399","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:0001078(transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0000122(negative regulation of transcription from RNA polymerase II promoter)","NA","NA","NA","zinc finger protein 668 [Source:HGNC Symbol;Acc:HGNC:25821]",{"v":0.257645550190597,"d":"0.26"},{"v":0.868542112325286,"d":"0.87"},{"v":0.296641402338939,"d":"0.30"},{"v":-1.75320812561626,"d":"-1.75"},{"v":0.0142223756894493,"d":"0.01"},{"v":0.372317060983366,"d":"0.37"},"down","yes"]
["MSTRG.15124","TMEM203;TPRN","ENST00000343666;ENST00000477345;ENST00000409012;ENST00000541945;ENST00000333046","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0007283(spermatogenesis);GO:0005515(protein binding);GO:0006874(cellular calcium ion homeostasis);GO:0007605(sensory perception of sound);GO:0019902(phosphatase binding);GO:0042995(cell projection);GO:0003674(molecular_function);GO:0032420(stereocilium);GO:0032420(stereocilium)","NA","NA","NA","transmembrane protein 203 [Source:HGNC Symbol;Acc:HGNC:28217];taperin [Source:HGNC Symbol;Acc:HGNC:26894]",{"v":2.4282457423953,"d":"2.43"},{"v":0.782696408817046,"d":"0.78"},{"v":3.10241073683385,"d":"3.10"},{"v":1.63338970144999,"d":"1.63"},{"v":0.014286888069003,"d":"0.01"},{"v":0.372778290759264,"d":"0.37"},"up","yes"]
["ENSG00000134460","IL2RA","ENST00000379959;ENST00000379954","GO:0005622(intracellular);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0043547(positive regulation of GTPase activity);GO:0002376(immune system process);GO:0005886(plasma membrane);GO:0006954(inflammatory response);GO:0000165(MAPK cascade);GO:0004911(interleukin-2 receptor activity);GO:0019976(interleukin-2 binding);GO:0038110(interleukin-2-mediated signaling pathway);GO:0006955(immune response);GO:0006915(apoptotic process);GO:0007166(cell surface receptor signaling pathway);GO:0005088(Ras guanyl-nucleotide exchange factor activity);GO:0008283(cell proliferation);GO:0045589(regulation of regulatory T cell differentiation);GO:0008144(drug binding);GO:0002437(inflammatory response to antigenic stimulus);GO:0002664(regulation of T cell tolerance induction);GO:0006924(activation-induced cell death of T cells);GO:0007219(Notch signaling pathway);GO:0042102(positive regulation of T cell proliferation);GO:0042104(positive regulation of activated T cell proliferation);GO:0042130(negative regulation of T cell proliferation);GO:0043029(T cell homeostasis);GO:0045582(positive regulation of T cell differentiation);GO:0046013(regulation of T cell homeostatic proliferation);GO:0050672(negative regulation of lymphocyte proliferation);GO:0050687(negative regulation of defense response to virus);GO:0050728(negative regulation of inflammatory response);GO:0050777(negative regulation of immune response);GO:0009897(external side of plasma membrane);GO:0009986(cell surface);GO:0009986(cell surface)","04630(Jak-STAT signaling pathway);04151(PI3K-Akt signaling pathway);04060(Cytokine-cytokine receptor interaction);04144(Endocytosis);04640(Hematopoietic cell lineage);04658(Th1 and Th2 cell differentiation);04659(Th17 cell differentiation);05200(Pathways in cancer);05166(HTLV-I infection);05162(Measles);05162(Measles)","K05068","NA","interleukin 2 receptor subunit alpha [Source:HGNC Symbol;Acc:HGNC:6008]",{"v":2.378639,"d":"2.38"},{"v":0.757998892947103,"d":"0.76"},{"v":3.13805075724035,"d":"3.14"},{"v":1.64986868775111,"d":"1.65"},{"v":0.0143201703285898,"d":"0.01"},{"v":0.372778290759264,"d":"0.37"},"up","yes"]
["MSTRG.13101","LMBRD1","ENST00000370577;ENST00000370570;ENST00000472827","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005765(lysosomal membrane);GO:0005764(lysosome);GO:0016032(viral process);GO:0031419(cobalamin binding);GO:0009235(cobalamin metabolic process);GO:0015889(cobalamin transport);GO:0015235(cobalamin transporter activity);GO:0005158(insulin receptor binding);GO:0038016(insulin receptor internalization);GO:0046325(negative regulation of glucose import);GO:0046627(negative regulation of insulin receptor signaling pathway);GO:0051898(negative regulation of protein kinase B signaling);GO:0005886(plasma membrane);GO:0045334(clathrin-coated endocytic vesicle);GO:0045334(clathrin-coated endocytic vesicle)","04977(Vitamin digestion and absorption);04977(Vitamin digestion and absorption)","K14617","NA","LMBR1 domain containing 1 [Source:HGNC Symbol;Acc:HGNC:23038]",{"v":8.52263508201499,"d":"8.52"},{"v":27.1368561715237,"d":"27.14"},{"v":0.314061254116764,"d":"0.31"},{"v":-1.6708821268786,"d":"-1.67"},{"v":0.014332864027698,"d":"0.01"},{"v":0.372778290759264,"d":"0.37"},"down","yes"]
["MSTRG.8658","OXER1","ENST00000378661","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0004930(G-protein coupled receptor activity);GO:0007186(G-protein coupled receptor signaling pathway);GO:0005886(plasma membrane);GO:0004871(signal transducer activity);GO:0007165(signal transduction);GO:0050646(5-oxo-6E,8Z,11Z,14Z-icosatetraenoic acid binding);GO:0050647(5-hydroxy-6E,8Z,11Z,14Z-icosatetraenoic acid binding);GO:0050648(5(S)-hydroxyperoxy-6E,8Z,11Z,14Z-icosatetraenoic acid binding);GO:0030817(regulation of cAMP biosynthetic process)","NA","NA","NA","oxoeicosanoid receptor 1 [Source:HGNC Symbol;Acc:HGNC:24884]",{"v":2.385678,"d":"2.39"},{"v":7.665031,"d":"7.67"},{"v":0.311241794064499,"d":"0.31"},{"v":-1.68389229407135,"d":"-1.68"},{"v":0.0144372863857134,"d":"0.01"},{"v":0.37468491951888,"d":"0.37"},"down","yes"]
["ENSG00000256223","ZNF10","ENST00000537119;ENST00000543271;ENST00000538918;ENST00000248211;ENST00000426665;ENST00000540609;ENST00000402932;ENST00000536877","GO:0003676(nucleic acid binding);GO:0006355(regulation of transcription, DNA-templated);GO:0005622(intracellular);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0005515(protein binding)","NA","NA","NA","zinc finger protein 10 [Source:HGNC Symbol;Acc:HGNC:12879]",{"v":0.48066434903447,"d":"0.48"},{"v":0.140405380978163,"d":"0.14"},{"v":3.42340404396059,"d":"3.42"},{"v":1.77543157508747,"d":"1.78"},{"v":0.0144943703416643,"d":"0.01"},{"v":0.375357435815746,"d":"0.38"},"up","yes"]
["ENSG00000078124","ACER3","ENST00000532485;ENST00000525325;ENST00000531352;ENST00000525194;ENST00000530334;ENST00000527508;ENST00000530921;ENST00000525861;ENST00000531461;ENST00000278544","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0006672(ceramide metabolic process);GO:0016811(hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides);GO:0016787(hydrolase activity);GO:0005794(Golgi apparatus);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0000139(Golgi membrane);GO:0008284(positive regulation of cell proliferation);GO:0030173(integral component of Golgi membrane);GO:0030176(integral component of endoplasmic reticulum membrane);GO:0030148(sphingolipid biosynthetic process);GO:0046512(sphingosine biosynthetic process);GO:0070774(phytoceramidase activity);GO:0071602(phytosphingosine biosynthetic process);GO:0071602(phytosphingosine biosynthetic process)","00600(Sphingolipid metabolism);00600(Sphingolipid metabolism)","K04711","EC:3.5.1.-","alkaline ceramidase 3 [Source:HGNC Symbol;Acc:HGNC:16066]",{"v":1.16154372470978,"d":"1.16"},{"v":0.372123906894101,"d":"0.37"},{"v":3.12138968550691,"d":"3.12"},{"v":1.64218847973501,"d":"1.64"},{"v":0.0145429379609078,"d":"0.01"},{"v":0.375806993401827,"d":"0.38"},"up","yes"]
["MSTRG.8774","C1D","ENST00000355848;ENST00000409302;ENST00000479484;ENST00000407324;ENST00000410067;ENST00000485709","GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005730(nucleolus);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0006915(apoptotic process);GO:0006364(rRNA processing);GO:0005654(nucleoplasm);GO:0000460(maturation of 5.8S rRNA);GO:0000176(nuclear exosome (RNase complex));GO:0003714(transcription corepressor activity);GO:0016922(ligand-dependent nuclear receptor binding);GO:0045892(negative regulation of transcription, DNA-templated);GO:0017053(transcriptional repressor complex);GO:0017053(transcriptional repressor complex)","03018(RNA degradation);03018(RNA degradation)","K12592","NA","C1D nuclear receptor corepressor [Source:HGNC Symbol;Acc:HGNC:29911]",{"v":1.9215596964535,"d":"1.92"},{"v":0.606489210834962,"d":"0.61"},{"v":3.16833286087326,"d":"3.17"},{"v":1.66372391101879,"d":"1.66"},{"v":0.0146010453415493,"d":"0.01"},{"v":0.37625065937388,"d":"0.38"},"up","yes"]
["ENSG00000075407","ZNF37A","ENST00000361085;ENST00000351773;ENST00000477790;ENST00000638053","GO:0003676(nucleic acid binding);GO:0006355(regulation of transcription, DNA-templated);GO:0005622(intracellular);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding)","NA","NA","NA","zinc finger protein 37A [Source:HGNC Symbol;Acc:HGNC:13102]",{"v":0.504729153070508,"d":"0.50"},{"v":0.161129173085671,"d":"0.16"},{"v":3.1324504644615,"d":"3.13"},{"v":1.64729169542398,"d":"1.65"},{"v":0.0146531120567347,"d":"0.01"},{"v":0.37625065937388,"d":"0.38"},"up","yes"]
["MSTRG.10961","TMEM115","ENST00000266025","GO:0006810(transport);GO:0005634(nucleus);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0015031(protein transport);GO:0005794(Golgi apparatus);GO:0005515(protein binding);GO:0004252(serine-type endopeptidase activity);GO:0006508(proteolysis);GO:0006890(retrograde vesicle-mediated transport, Golgi to ER);GO:0006486(protein glycosylation);GO:0032580(Golgi cisterna membrane);GO:0003674(molecular_function);GO:0008285(negative regulation of cell proliferation);GO:0042802(identical protein binding);GO:0006888(ER to Golgi vesicle-mediated transport);GO:0000139(Golgi membrane);GO:0017119(Golgi transport complex)","NA","NA","NA","transmembrane protein 115 [Source:HGNC Symbol;Acc:HGNC:30055]",{"v":2.339925,"d":"2.34"},{"v":7.494482,"d":"7.49"},{"v":0.3122197104483,"d":"0.31"},{"v":-1.67936647727555,"d":"-1.68"},{"v":0.0146538414919739,"d":"0.01"},{"v":0.37625065937388,"d":"0.38"},"down","yes"]
["MSTRG.3932","ALOX5AP","ENST00000617770;ENST00000380490;ENST00000479597","GO:0005634(nucleus);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0008047(enzyme activator activity);GO:0043085(positive regulation of catalytic activity);GO:0006691(leukotriene metabolic process);GO:0005515(protein binding);GO:0019370(leukotriene biosynthetic process);GO:0047485(protein N-terminus binding);GO:0031965(nuclear membrane);GO:0005635(nuclear envelope);GO:0019372(lipoxygenase pathway);GO:0071277(cellular response to calcium ion);GO:0050544(arachidonic acid binding);GO:2001300(lipoxin metabolic process);GO:0070207(protein homotrimerization);GO:0055114(oxidation-reduction process);GO:0004051(arachidonate 5-lipoxygenase activity);GO:0019899(enzyme binding);GO:0042803(protein homodimerization activity);GO:0046982(protein heterodimerization activity);GO:0002540(leukotriene production involved in inflammatory response);GO:0002675(positive regulation of acute inflammatory response);GO:0005829(cytosol);GO:0005829(cytosol)","04664(Fc epsilon RI signaling pathway);04664(Fc epsilon RI signaling pathway)","K20735","NA","arachidonate 5-lipoxygenase activating protein [Source:HGNC Symbol;Acc:HGNC:436]",{"v":21.779411580758,"d":"21.78"},{"v":68.7567893113703,"d":"68.76"},{"v":0.316760159962215,"d":"0.32"},{"v":-1.65853720088187,"d":"-1.66"},{"v":0.014977743223229,"d":"0.01"},{"v":0.382655000620201,"d":"0.38"},"down","yes"]
["ENSG00000182141","ZNF708","ENST00000356929;ENST00000602023;ENST00000601295;ENST00000598046","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016021(integral component of membrane)","NA","NA","NA","zinc finger protein 708 [Source:HGNC Symbol;Acc:HGNC:12945]",{"v":2.30364370127168,"d":"2.30"},{"v":0.743770612716763,"d":"0.74"},{"v":3.09725022995623,"d":"3.10"},{"v":1.63098794450226,"d":"1.63"},{"v":0.0150089788396034,"d":"0.02"},{"v":0.382655000620201,"d":"0.38"},"up","yes"]
["MSTRG.13659","CRCP;ASL;AC068533.4","ENST00000395326;ENST00000395332;ENST00000304874;ENST00000362000;ENST00000487982;ENST00000492264;ENST00000496336;ENST00000488343;ENST00000493708;ENST00000360415;ENST00000338592;ENST00000450043;ENST00000464970;ENST00000398684;ENST00000380839","GO:0005634(nucleus);GO:0016020(membrane);GO:0003824(catalytic activity);GO:0006351(transcription, DNA-templated);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0003899(DNA-directed 5'-3' RNA polymerase activity);GO:0000166(nucleotide binding);GO:0002376(immune system process);GO:0045087(innate immune response);GO:0044237(cellular metabolic process);GO:0001635(calcitonin gene-related peptide receptor activity);GO:0007218(neuropeptide signaling pathway);GO:0001669(acrosomal vesicle);GO:0051607(defense response to virus);GO:0005666(DNA-directed RNA polymerase III complex);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0001056(RNA polymerase III activity);GO:0032481(positive regulation of type I interferon production);GO:0006383(transcription from RNA polymerase III promoter);GO:0006384(transcription initiation from RNA polymerase III promoter);GO:0009360(DNA polymerase III complex);GO:0016829(lyase activity);GO:0008652(cellular amino acid biosynthetic process);GO:0000050(urea cycle);GO:0004056(argininosuccinate lyase activity);GO:0006520(cellular amino acid metabolic process);GO:0007626(locomotory behavior);GO:0009791(post-embryonic development);GO:0019676(ammonia assimilation cycle);GO:0042450(arginine biosynthetic process via ornithine);GO:0042802(identical protein binding);GO:0070062(extracellular exosome);GO:0005737(cytoplasm);GO:0006526(arginine biosynthetic process);GO:0006526(arginine biosynthetic process)","00250(Alanine, aspartate and glutamate metabolism);00220(Arginine biosynthesis);00220(Arginine biosynthesis)","K01755","EC:4.3.2.1","CGRP receptor component [Source:HGNC Symbol;Acc:HGNC:17888];argininosuccinate lyase [Source:HGNC Symbol;Acc:HGNC:746]",{"v":1.16055722672606,"d":"1.16"},{"v":3.70105263236823,"d":"3.70"},{"v":0.313574904765254,"d":"0.31"},{"v":-1.67311798893999,"d":"-1.67"},{"v":0.015027110139549,"d":"0.02"},{"v":0.382655000620201,"d":"0.38"},"down","yes"]
["ENSG00000181666","HKR1","ENST00000392153;ENST00000544914;ENST00000592768;ENST00000590166;ENST00000587829;ENST00000588820;ENST00000589801;ENST00000592362;ENST00000591471;ENST00000590386;ENST00000590582;ENST00000591259;ENST00000324411;ENST00000587570;ENST00000587437;ENST00000591485;ENST00000589218;ENST00000585623;ENST00000591417;ENST00000541583;ENST00000589392","GO:0003676(nucleic acid binding);GO:0006355(regulation of transcription, DNA-templated);GO:0005622(intracellular);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0007275(multicellular organism development);GO:0007275(multicellular organism development)","NA","NA","NA","HKR1, GLI-Kruppel zinc finger family member [Source:HGNC Symbol;Acc:HGNC:4928]",{"v":0.347590778842149,"d":"0.35"},{"v":1.12863286227961,"d":"1.13"},{"v":0.307975064752311,"d":"0.31"},{"v":-1.6991145472609,"d":"-1.70"},{"v":0.0150303782837863,"d":"0.02"},{"v":0.382655000620201,"d":"0.38"},"down","yes"]
["MSTRG.13120","OGFRL1","ENST00000370435;MSTRG.13120.2;ENST00000467503","GO:0016020(membrane);GO:0004872(receptor activity);GO:0004872(receptor activity)","NA","NA","NA","opioid growth factor receptor like 1 [Source:HGNC Symbol;Acc:HGNC:21378]",{"v":6.19738123127899,"d":"6.20"},{"v":19.4866288471394,"d":"19.49"},{"v":0.318032497046751,"d":"0.32"},{"v":-1.65275390506074,"d":"-1.65"},{"v":0.0152247751351538,"d":"0.02"},{"v":0.386786375901946,"d":"0.39"},"down","yes"]
["ENSG00000171466","ZNF562","ENST00000587392;ENST00000585350;ENST00000453372;ENST00000588653;ENST00000293648;ENST00000590155","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0005622(intracellular);GO:0005622(intracellular)","NA","NA","NA","zinc finger protein 562 [Source:HGNC Symbol;Acc:HGNC:25950]",{"v":0.207184904051665,"d":"0.21"},{"v":0.660842605981395,"d":"0.66"},{"v":0.313516262687061,"d":"0.31"},{"v":-1.67338781457312,"d":"-1.67"},{"v":0.0152844185097197,"d":"0.02"},{"v":0.387484142513779,"d":"0.39"},"down","yes"]
["MSTRG.8423","LILRA2","ENST00000251376;MSTRG.8423.2;ENST00000472992;ENST00000495786;ENST00000391737;ENST00000439534;MSTRG.8423.3;ENST00000251377;MSTRG.8423.4;ENST00000629481;ENST00000391738","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005576(extracellular region);GO:0002376(immune system process);GO:0002250(adaptive immune response);GO:0007165(signal transduction);GO:0004872(receptor activity);GO:0006952(defense response);GO:0003823(antigen binding);GO:0003823(antigen binding)","04380(Osteoclast differentiation);04380(Osteoclast differentiation)","K06512","NA","leukocyte immunoglobulin like receptor A2 [Source:HGNC Symbol;Acc:HGNC:6603]",{"v":12.5260949856048,"d":"12.53"},{"v":39.2861813875491,"d":"39.29"},{"v":0.318842263187602,"d":"0.32"},{"v":-1.6490852207348,"d":"-1.65"},{"v":0.0154919859973141,"d":"0.02"},{"v":0.39128870172853,"d":"0.39"},"down","yes"]
["MSTRG.5893","ZNF267","ENST00000300870;ENST00000394846;ENST00000575471;ENST00000566541;ENST00000561814;ENST00000562971","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0005622(intracellular);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0007275(multicellular organism development);GO:0007275(multicellular organism development)","NA","NA","NA","zinc finger protein 267 [Source:HGNC Symbol;Acc:HGNC:13060]",{"v":3.03616445539239,"d":"3.04"},{"v":9.54856702936997,"d":"9.55"},{"v":0.317970690895671,"d":"0.32"},{"v":-1.65303430437203,"d":"-1.65"},{"v":0.0154994777216832,"d":"0.02"},{"v":0.39128870172853,"d":"0.39"},"down","yes"]
["ENSG00000109381","ELF2","ENST00000358635;ENST00000394235;ENST00000510408;ENST00000379549;ENST00000515489;ENST00000511006;ENST00000514577;ENST00000504314;ENST00000379550;ENST00000512627;ENST00000420916;ENST00000511184;ENST00000514606","GO:0005634(nucleus);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0043565(sequence-specific DNA binding);GO:0005515(protein binding);GO:0016604(nuclear body);GO:0045893(positive regulation of transcription, DNA-templated);GO:0000981(RNA polymerase II transcription factor activity, sequence-specific DNA binding);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0030154(cell differentiation);GO:0050855(regulation of B cell receptor signaling pathway);GO:0050855(regulation of B cell receptor signaling pathway)","NA","NA","NA","E74 like ETS transcription factor 2 [Source:HGNC Symbol;Acc:HGNC:3317]",{"v":1.03597381238318,"d":"1.04"},{"v":3.2762455192757,"d":"3.28"},{"v":0.31620762433342,"d":"0.32"},{"v":-1.6610559408046,"d":"-1.66"},{"v":0.0155888682649472,"d":"0.02"},{"v":0.391910920259449,"d":"0.39"},"down","yes"]
["MSTRG.3968","KBTBD7","ENST00000379483","GO:0016567(protein ubiquitination);GO:0005515(protein binding);GO:0004842(ubiquitin-protein transferase activity);GO:0003674(molecular_function);GO:0008150(biological_process);GO:0005575(cellular_component);GO:0005829(cytosol);GO:0000165(MAPK cascade);GO:0043687(post-translational protein modification);GO:0031463(Cul3-RING ubiquitin ligase complex)","NA","NA","NA","kelch repeat and BTB domain containing 7 [Source:HGNC Symbol;Acc:HGNC:25266]",{"v":1.308034,"d":"1.31"},{"v":4.118591,"d":"4.12"},{"v":0.317592594166306,"d":"0.32"},{"v":-1.65475082372927,"d":"-1.65"},{"v":0.015616810406234,"d":"0.02"},{"v":0.391910920259449,"d":"0.39"},"down","yes"]
["MSTRG.8542","TP53I3","ENST00000407482;ENST00000413037;ENST00000238721;ENST00000335934;ENST00000470636","GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0042803(protein homodimerization activity);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0042981(regulation of apoptotic process);GO:0070402(NADPH binding);GO:0003960(NADPH:quinone reductase activity);GO:0006739(NADP metabolic process);GO:0048038(quinone binding);GO:0048038(quinone binding)","04115(p53 signaling pathway);04115(p53 signaling pathway)","K10133","EC:1.-.-.-","tumor protein p53 inducible protein 3 [Source:HGNC Symbol;Acc:HGNC:19373]",{"v":0.343948026384083,"d":"0.34"},{"v":1.15960050302768,"d":"1.16"},{"v":0.296609069663255,"d":"0.30"},{"v":-1.75336538192912,"d":"-1.75"},{"v":0.0156217606481096,"d":"0.02"},{"v":0.391910920259449,"d":"0.39"},"down","yes"]
["MSTRG.684","PKN2","ENST00000370521;ENST00000316005;ENST00000370513;ENST00000495119;ENST00000449189;ENST00000436111","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0007165(signal transduction);GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0016740(transferase activity);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0007155(cell adhesion);GO:0051301(cell division);GO:0005856(cytoskeleton);GO:0042995(cell projection);GO:0005515(protein binding);GO:0007049(cell cycle);GO:0006915(apoptotic process);GO:0004697(protein kinase C activity);GO:0030054(cell junction);GO:0048471(perinuclear region of cytoplasm);GO:0030496(midbody);GO:0035556(intracellular signal transduction);GO:0005829(cytosol);GO:0045296(cadherin binding);GO:0030027(lamellipodium);GO:0032154(cleavage furrow);GO:0043296(apical junction complex);GO:0018105(peptidyl-serine phosphorylation);GO:0070063(RNA polymerase binding);GO:0045070(positive regulation of viral genome replication);GO:0032467(positive regulation of cytokinesis);GO:0042826(histone deacetylase binding);GO:2000145(regulation of cell motility);GO:0043297(apical junction assembly);GO:0045931(positive regulation of mitotic cell cycle);GO:0010631(epithelial cell migration);GO:0043234(protein complex);GO:0043234(protein complex)","04151(PI3K-Akt signaling pathway);05132(Salmonella infection);05132(Salmonella infection)","K06071","EC:2.7.11.13","protein kinase N2 [Source:HGNC Symbol;Acc:HGNC:9406]",{"v":2.17954328101832,"d":"2.18"},{"v":6.83270416212058,"d":"6.83"},{"v":0.318986923669454,"d":"0.32"},{"v":-1.64843081053326,"d":"-1.65"},{"v":0.0157016646324903,"d":"0.02"},{"v":0.393096560300307,"d":"0.39"},"down","yes"]
["ENSG00000125780","TGM3","ENST00000381458","GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0016740(transferase activity);GO:0016746(transferase activity, transferring acyl groups);GO:0003824(catalytic activity);GO:0005509(calcium ion binding);GO:0003810(protein-glutamine gamma-glutamyltransferase activity);GO:0018149(peptide cross-linking);GO:0031424(keratinization);GO:0031234(extrinsic component of cytoplasmic side of plasma membrane);GO:0070062(extracellular exosome);GO:0031069(hair follicle morphogenesis);GO:0006464(cellular protein modification process);GO:0030216(keratinocyte differentiation);GO:0051262(protein tetramerization);GO:0043163(cell envelope organization)","NA","NA","NA","transglutaminase 3 [Source:HGNC Symbol;Acc:HGNC:11779]",{"v":0.614734438173041,"d":"0.61"},{"v":1.97255173338284,"d":"1.97"},{"v":0.311644266545445,"d":"0.31"},{"v":-1.68202792377996,"d":"-1.68"},{"v":0.0158353371202439,"d":"0.02"},{"v":0.393352766353947,"d":"0.39"},"down","yes"]
["MSTRG.6101","CMTR2","ENST00000564690;ENST00000567610;ENST00000563876;ENST00000568910;ENST00000564183;ENST00000434935;ENST00000565850;ENST00000338099","GO:0006397(mRNA processing);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0008168(methyltransferase activity);GO:0016740(transferase activity);GO:0032259(methylation);GO:0006370(7-methylguanosine mRNA capping);GO:0004483(mRNA (nucleoside-2'-O-)-methyltransferase activity);GO:0097310(cap2 mRNA methylation);GO:0097310(cap2 mRNA methylation)","NA","NA","NA","cap methyltransferase 2 [Source:HGNC Symbol;Acc:HGNC:25635]",{"v":0.215898316671063,"d":"0.22"},{"v":0.702754996307043,"d":"0.70"},{"v":0.307217049762154,"d":"0.31"},{"v":-1.7026698107139,"d":"-1.70"},{"v":0.0158482919887327,"d":"0.02"},{"v":0.393352766353947,"d":"0.39"},"down","yes"]
["ENSG00000122547","EEPD1","ENST00000242108;ENST00000487069;ENST00000468591","GO:0003677(DNA binding);GO:0006281(DNA repair);GO:0006281(DNA repair)","NA","NA","NA","endonuclease/exonuclease/phosphatase family domain containing 1 [Source:HGNC Symbol;Acc:HGNC:22223]",{"v":1.5767606385393,"d":"1.58"},{"v":4.95953507014648,"d":"4.96"},{"v":0.317925091009132,"d":"0.32"},{"v":-1.65324121478773,"d":"-1.65"},{"v":0.0159201913528594,"d":"0.02"},{"v":0.393352766353947,"d":"0.39"},"down","yes"]
["ENSG00000030419","IKZF2","ENST00000412444;ENST00000434687;ENST00000374319;ENST00000442445;ENST00000431520;ENST00000452786;ENST00000451136;ENST00000439848;ENST00000342002;ENST00000457361;ENST00000484040","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0003674(molecular_function);GO:0008150(biological_process);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0044212(transcription regulatory region DNA binding);GO:0042803(protein homodimerization activity);GO:0046982(protein heterodimerization activity);GO:0046982(protein heterodimerization activity)","NA","NA","NA","IKAROS family zinc finger 2 [Source:HGNC Symbol;Acc:HGNC:13177]",{"v":0.187190181127451,"d":"0.19"},{"v":0.60362506004902,"d":"0.60"},{"v":0.3101100227884,"d":"0.31"},{"v":-1.68914794012855,"d":"-1.69"},{"v":0.0159296562849985,"d":"0.02"},{"v":0.393352766353947,"d":"0.39"},"down","yes"]
["ENSG00000112394","SLC16A10","ENST00000368850;ENST00000439288;ENST00000368851;ENST00000419619;ENST00000612036","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0055085(transmembrane transport);GO:0005887(integral component of plasma membrane);GO:0005886(plasma membrane);GO:0003333(amino acid transmembrane transport);GO:0015173(aromatic amino acid transmembrane transporter activity);GO:0015349(thyroid hormone transmembrane transporter activity);GO:0070327(thyroid hormone transport);GO:0016323(basolateral plasma membrane);GO:0015171(amino acid transmembrane transporter activity);GO:0008028(monocarboxylic acid transmembrane transporter activity);GO:0006865(amino acid transport);GO:0015718(monocarboxylic acid transport);GO:0015801(aromatic amino acid transport);GO:0015801(aromatic amino acid transport)","04919(Thyroid hormone signaling pathway);04974(Protein digestion and absorption);04974(Protein digestion and absorption)","K08187","NA","solute carrier family 16 member 10 [Source:HGNC Symbol;Acc:HGNC:17027]",{"v":0.230556093797277,"d":"0.23"},{"v":0.0722435367980778,"d":"0.07"},{"v":3.19137329117325,"d":"3.19"},{"v":1.67417736882616,"d":"1.67"},{"v":0.0159938383539695,"d":"0.02"},{"v":0.393352766353947,"d":"0.39"},"up","yes"]
["MSTRG.13011","TREML1","ENST00000373127;ENST00000437044;ENST00000590581;ENST00000426005","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005886(plasma membrane);GO:0045087(innate immune response);GO:0050776(regulation of immune response);GO:0050776(regulation of immune response)","NA","NA","NA","triggering receptor expressed on myeloid cells like 1 [Source:HGNC Symbol;Acc:HGNC:20434]",{"v":7.12909650438301,"d":"7.13"},{"v":22.3527239635873,"d":"22.35"},{"v":0.318936363907877,"d":"0.32"},{"v":-1.64865949733266,"d":"-1.65"},{"v":0.0160141142268833,"d":"0.02"},{"v":0.393352766353947,"d":"0.39"},"down","yes"]
["MSTRG.7974","MAP1S","ENST00000324096;ENST00000594212;ENST00000598769;ENST00000598756;ENST00000600608;ENST00000594365;ENST00000596637;ENST00000601097;ENST00000544059;ENST00000601544;ENST00000597067;ENST00000599494;ENST00000593593","GO:0051015(actin filament binding);GO:0006915(apoptotic process);GO:0008017(microtubule binding);GO:0000226(microtubule cytoskeleton organization);GO:0005874(microtubule);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005730(nucleolus);GO:0005829(cytosol);GO:0003677(DNA binding);GO:0030054(cell junction);GO:0005856(cytoskeleton);GO:0042995(cell projection);GO:0005515(protein binding);GO:0045202(synapse);GO:0005819(spindle);GO:0048471(perinuclear region of cytoplasm);GO:0007399(nervous system development);GO:0015631(tubulin binding);GO:0001578(microtubule bundle formation);GO:0007420(brain development);GO:0030425(dendrite);GO:0048487(beta-tubulin binding);GO:0047497(mitochondrion transport along microtubule);GO:0006914(autophagy);GO:0042802(identical protein binding);GO:0010848(regulation of chromatin disassembly);GO:0048812(neuron projection morphogenesis);GO:0015630(microtubule cytoskeleton);GO:0043025(neuronal cell body);GO:0043025(neuronal cell body)","NA","NA","NA","microtubule associated protein 1S [Source:HGNC Symbol;Acc:HGNC:15715]",{"v":1.35436476448413,"d":"1.35"},{"v":4.25954300992063,"d":"4.26"},{"v":0.317960110117392,"d":"0.32"},{"v":-1.65308231222549,"d":"-1.65"},{"v":0.0160190299253628,"d":"0.02"},{"v":0.393352766353947,"d":"0.39"},"down","yes"]
["MSTRG.13154","SLC35A1;CFAP206;AL049697.1","ENST00000369552;ENST00000296885;ENST00000506888;ENST00000507897;ENST00000369562","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005794(Golgi apparatus);GO:0000139(Golgi membrane);GO:0008643(carbohydrate transport);GO:0005351(sugar:proton symporter activity);GO:0015992(proton transport);GO:0005887(integral component of plasma membrane);GO:0005975(carbohydrate metabolic process);GO:0006464(cellular protein modification process);GO:0005456(CMP-N-acetylneuraminate transmembrane transporter activity);GO:0015782(CMP-N-acetylneuraminate transport);GO:0005737(cytoplasm);GO:0031514(motile cilium);GO:0005856(cytoskeleton);GO:0042995(cell projection);GO:0005515(protein binding);GO:0005929(cilium);GO:0030030(cell projection organization);GO:0003341(cilium movement);GO:0035082(axoneme assembly);GO:0001534(radial spoke);GO:0097649(A axonemal microtubule);GO:0097649(A axonemal microtubule)","NA","NA","NA","solute carrier family 35 member A1 [Source:HGNC Symbol;Acc:HGNC:11021];cilia and flagella associated protein 206 [Source:HGNC Symbol;Acc:HGNC:21405]",{"v":0.615434833527164,"d":"0.62"},{"v":1.95081586442931,"d":"1.95"},{"v":0.315475614458981,"d":"0.32"},{"v":-1.66439960238561,"d":"-1.66"},{"v":0.0160239180226787,"d":"0.02"},{"v":0.393352766353947,"d":"0.39"},"down","yes"]
["MSTRG.13860","AC007384.1","ENST00000417026;ENST00000415513","NA","NA","NA","NA",null,{"v":2.06849782978723,"d":"2.07"},{"v":0.644564563829787,"d":"0.64"},{"v":3.20913985326297,"d":"3.21"},{"v":1.68218666316675,"d":"1.68"},{"v":0.0161222200393313,"d":"0.02"},{"v":0.393352766353947,"d":"0.39"},"up","yes"]
["MSTRG.3848","GTF2H3;AC117503.3","ENST00000543341;ENST00000538845;ENST00000539994;ENST00000537368;ENST00000623811;ENST00000228955;ENST00000539429","GO:0005654(nucleoplasm);GO:0006355(regulation of transcription, DNA-templated);GO:0006289(nucleotide-excision repair);GO:0000439(core TFIIH complex);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006351(transcription, DNA-templated);GO:0005515(protein binding);GO:0006281(DNA repair);GO:0006974(cellular response to DNA damage stimulus);GO:0006366(transcription from RNA polymerase II promoter);GO:0047485(protein N-terminus binding);GO:0006368(transcription elongation from RNA polymerase II promoter);GO:0006370(7-methylguanosine mRNA capping);GO:0006367(transcription initiation from RNA polymerase II promoter);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0004672(protein kinase activity);GO:0008135(translation factor activity, RNA binding);GO:0006361(transcription initiation from RNA polymerase I promoter);GO:0006362(transcription elongation from RNA polymerase I promoter);GO:0006363(termination of RNA polymerase I transcription);GO:0003684(damaged DNA binding);GO:0008094(DNA-dependent ATPase activity);GO:0006283(transcription-coupled nucleotide-excision repair);GO:0005669(transcription factor TFIID complex);GO:0008353(RNA polymerase II carboxy-terminal domain kinase activity);GO:0006293(nucleotide-excision repair, preincision complex stabilization);GO:0006295(nucleotide-excision repair, DNA incision, 3'-to lesion);GO:0006296(nucleotide-excision repair, DNA incision, 5'-to lesion);GO:0033683(nucleotide-excision repair, DNA incision);GO:0070911(global genome nucleotide-excision repair);GO:0000717(nucleotide-excision repair, DNA duplex unwinding);GO:0006294(nucleotide-excision repair, preincision complex assembly);GO:0005675(holo TFIIH complex);GO:0070816(phosphorylation of RNA polymerase II C-terminal domain);GO:0006412(translation);GO:0000438(core TFIIH complex portion of holo TFIIH complex);GO:0097550(transcriptional preinitiation complex);GO:0097550(transcriptional preinitiation complex)","03022(Basal transcription factors);03420(Nucleotide excision repair);05203(Viral carcinogenesis);05203(Viral carcinogenesis)","K03143","NA","general transcription factor IIH subunit 3 [Source:HGNC Symbol;Acc:HGNC:4657]",{"v":1.24467678208232,"d":"1.24"},{"v":0.400474988113581,"d":"0.40"},{"v":3.10800129602428,"d":"3.11"},{"v":1.63598710534389,"d":"1.64"},{"v":0.0161809165058176,"d":"0.02"},{"v":0.393352766353947,"d":"0.39"},"up","yes"]
["ENSG00000048544","MRPS10","ENST00000053468","GO:0030529(intracellular ribonucleoprotein complex);GO:0005840(ribosome);GO:0005739(mitochondrion);GO:0003674(molecular_function);GO:0008150(biological_process);GO:0005743(mitochondrial inner membrane);GO:0070125(mitochondrial translational elongation);GO:0070126(mitochondrial translational termination);GO:0005763(mitochondrial small ribosomal subunit)","03010(Ribosome)","K02946","NA","mitochondrial ribosomal protein S10 [Source:HGNC Symbol;Acc:HGNC:14502]",{"v":1.446938,"d":"1.45"},{"v":4.569377,"d":"4.57"},{"v":0.316659798480187,"d":"0.32"},{"v":-1.65899437313135,"d":"-1.66"},{"v":0.0162289272109707,"d":"0.02"},{"v":0.393352766353947,"d":"0.39"},"down","yes"]
["MSTRG.808","CAPZA1","ENST00000263168;ENST00000498626;ENST00000466066;ENST00000485542;ENST00000476936;ENST00000476820","GO:0005737(cytoplasm);GO:0003779(actin binding);GO:0051016(barbed-end actin filament capping);GO:0051693(actin filament capping);GO:0008290(F-actin capping protein complex);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0005829(cytosol);GO:0045296(cadherin binding);GO:0070062(extracellular exosome);GO:0071203(WASH complex);GO:0045087(innate immune response);GO:0019886(antigen processing and presentation of exogenous peptide antigen via MHC class II);GO:0035722(interleukin-12-mediated signaling pathway);GO:0006888(ER to Golgi vesicle-mediated transport);GO:0006461(protein complex assembly);GO:0006928(movement of cell or subcellular component);GO:0015629(actin cytoskeleton);GO:0007596(blood coagulation);GO:0007596(blood coagulation)","04144(Endocytosis);04144(Endocytosis)","K10364","NA","capping actin protein of muscle Z-line alpha subunit 1 [Source:HGNC Symbol;Acc:HGNC:1488]",{"v":13.6833282554479,"d":"13.68"},{"v":42.5447731029056,"d":"42.54"},{"v":0.321621841121381,"d":"0.32"},{"v":-1.63656271260073,"d":"-1.64"},{"v":0.0162339898510124,"d":"0.02"},{"v":0.393352766353947,"d":"0.39"},"down","yes"]
["ENSG00000141956","PRDM15","ENST00000422911;ENST00000447016;ENST00000491486;ENST00000465955;ENST00000398548;ENST00000433067;ENST00000495217;ENST00000486812;ENST00000489661","GO:0003676(nucleic acid binding);GO:0005654(nucleoplasm);GO:0016604(nuclear body);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0008168(methyltransferase activity);GO:0016740(transferase activity);GO:0032259(methylation);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0003677(DNA binding)","NA","NA","NA","PR/SET domain 15 [Source:HGNC Symbol;Acc:HGNC:13999]",{"v":0.813042500307598,"d":"0.81"},{"v":0.267706541833282,"d":"0.27"},{"v":3.03706623954648,"d":"3.04"},{"v":1.60267837456499,"d":"1.60"},{"v":0.0162865394548131,"d":"0.02"},{"v":0.393352766353947,"d":"0.39"},"up","yes"]
["ENSG00000162676","GFI1","ENST00000370332;ENST00000483490;ENST00000294702;ENST00000427103","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0030097(hemopoiesis);GO:0051569(regulation of histone H3-K4 methylation);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0071222(cellular response to lipopolysaccharide);GO:0032088(negative regulation of NF-kappaB transcription factor activity);GO:0045892(negative regulation of transcription, DNA-templated);GO:0016363(nuclear matrix);GO:0044212(transcription regulatory region DNA binding);GO:0001078(transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0017053(transcriptional repressor complex);GO:0010956(negative regulation of calcidiol 1-monooxygenase activity);GO:0010977(negative regulation of neuron projection development);GO:0016604(nuclear body);GO:0010957(negative regulation of vitamin D biosynthetic process);GO:0016032(viral process);GO:0034121(regulation of toll-like receptor signaling pathway);GO:0000083(regulation of transcription involved in G1/S transition of mitotic cell cycle);GO:0070105(positive regulation of interleukin-6-mediated signaling pathway);GO:0070105(positive regulation of interleukin-6-mediated signaling pathway)","NA","NA","NA","growth factor independent 1 transcriptional repressor [Source:HGNC Symbol;Acc:HGNC:4237]",{"v":2.75206519630415,"d":"2.75"},{"v":0.902592424719782,"d":"0.90"},{"v":3.04906746492865,"d":"3.05"},{"v":1.60836807236839,"d":"1.61"},{"v":0.0162883622917651,"d":"0.02"},{"v":0.393352766353947,"d":"0.39"},"up","yes"]
["MSTRG.14302","TACC1","ENST00000276520;ENST00000317827;MSTRG.14302.23;ENST00000522955;ENST00000521154;ENST00000524193;ENST00000520615;ENST00000518415;ENST00000523834;ENST00000524354;ENST00000519416;ENST00000522904;ENST00000520340;ENST00000521642;ENST00000519093;ENST00000520611;ENST00000521866;ENST00000523239;ENST00000517336;ENST00000521568;ENST00000520973;ENST00000522548;ENST00000521935;ENST00000522752;ENST00000518809","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0051301(cell division);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0007049(cell cycle);GO:0005815(microtubule organizing center);GO:0030496(midbody);GO:0000226(microtubule cytoskeleton organization);GO:0008283(cell proliferation);GO:0021987(cerebral cortex development);GO:0015630(microtubule cytoskeleton);GO:0015630(microtubule cytoskeleton)","NA","NA","NA","transforming acidic coiled-coil containing protein 1 [Source:HGNC Symbol;Acc:HGNC:11522]",{"v":2.01652533215242,"d":"2.02"},{"v":6.28624470595182,"d":"6.29"},{"v":0.320783778945667,"d":"0.32"},{"v":-1.6403269039247,"d":"-1.64"},{"v":0.0162914812142989,"d":"0.02"},{"v":0.393352766353947,"d":"0.39"},"down","yes"]
["MSTRG.3142","KLRG1","ENST00000356986;ENST00000538029;ENST00000539240;ENST00000266551;ENST00000544226;ENST00000543895;ENST00000541957","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0030246(carbohydrate binding);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0002376(immune system process);GO:0045087(innate immune response);GO:0006954(inflammatory response);GO:0004872(receptor activity);GO:0007166(cell surface receptor signaling pathway);GO:0006968(cellular defense response);GO:0006968(cellular defense response)","NA","NA","NA","killer cell lectin like receptor G1 [Source:HGNC Symbol;Acc:HGNC:6380]",{"v":1.48489007351809,"d":"1.48"},{"v":0.472548086220169,"d":"0.47"},{"v":3.14230470256577,"d":"3.14"},{"v":1.65182308246747,"d":"1.65"},{"v":0.0162983443586157,"d":"0.02"},{"v":0.393352766353947,"d":"0.39"},"up","yes"]
["MSTRG.567","ECHDC2","ENST00000460612;ENST00000492992;ENST00000371520;ENST00000486170;ENST00000498544;ENST00000487851;ENST00000544365;ENST00000488268;ENST00000544531;ENST00000487866;ENST00000479183;ENST00000371522;ENST00000480312;ENST00000358358;ENST00000474789;ENST00000476477;ENST00000539680;ENST00000487040;ENST00000463923;ENST00000479593;ENST00000536120;ENST00000493896;ENST00000542552","GO:0003824(catalytic activity);GO:0016829(lyase activity);GO:0006629(lipid metabolic process);GO:0008152(metabolic process);GO:0006631(fatty acid metabolic process);GO:0005739(mitochondrion);GO:0006635(fatty acid beta-oxidation);GO:0004300(enoyl-CoA hydratase activity);GO:0004300(enoyl-CoA hydratase activity)","NA","NA","NA","enoyl-CoA hydratase domain containing 2 [Source:HGNC Symbol;Acc:HGNC:23408]",{"v":0.995813476927065,"d":"1.00"},{"v":0.326929002246803,"d":"0.33"},{"v":3.04596248752294,"d":"3.05"},{"v":1.60689817445886,"d":"1.61"},{"v":0.0163198871148161,"d":"0.02"},{"v":0.393352766353947,"d":"0.39"},"up","yes"]
["MSTRG.2061","IFITM2;IFITM1","MSTRG.2061.5;ENST00000528780;ENST00000408968;MSTRG.2061.6;MSTRG.2061.1;ENST00000399817;ENST00000602569;ENST00000616316;MSTRG.2061.4;ENST00000533141;ENST00000399815;MSTRG.2061.12;ENST00000527146;MSTRG.2061.11;ENST00000328221;ENST00000525554","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005886(plasma membrane);GO:0002376(immune system process);GO:0045087(innate immune response);GO:0050776(regulation of immune response);GO:0009607(response to biotic stimulus);GO:0051607(defense response to virus);GO:0005515(protein binding);GO:0008285(negative regulation of cell proliferation);GO:0009615(response to virus);GO:0045071(negative regulation of viral genome replication);GO:0001503(ossification);GO:0007166(cell surface receptor signaling pathway);GO:0046597(negative regulation of viral entry into host cell);GO:0060337(type I interferon signaling pathway);GO:0005057(signal transducer activity, downstream of receptor);GO:0035456(response to interferon-beta);GO:0030336(negative regulation of cell migration);GO:0034341(response to interferon-gamma);GO:0045669(positive regulation of osteoblast differentiation);GO:0035455(response to interferon-alpha);GO:0006955(immune response);GO:0035455(response to interferon-alpha)","04662(B cell receptor signaling pathway);04662(B cell receptor signaling pathway)","K19831","NA","interferon induced transmembrane protein 1 [Source:HGNC Symbol;Acc:HGNC:5412];interferon induced transmembrane protein 2 [Source:HGNC Symbol;Acc:HGNC:5413]",{"v":51.7002930196528,"d":"51.70"},{"v":160.55659357812,"d":"160.56"},{"v":0.322006663616077,"d":"0.32"},{"v":-1.63483755106177,"d":"-1.63"},{"v":0.0163233909171701,"d":"0.02"},{"v":0.393352766353947,"d":"0.39"},"down","yes"]
["ENSG00000146676","PURB","ENST00000395699","GO:0003723(RNA binding);GO:0005634(nucleus);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0030154(cell differentiation);GO:0045892(negative regulation of transcription, DNA-templated);GO:0003729(mRNA binding);GO:0008283(cell proliferation);GO:0008134(transcription factor binding);GO:0003697(single-stranded DNA binding);GO:0005662(DNA replication factor A complex);GO:0000977(RNA polymerase II regulatory region sequence-specific DNA binding);GO:0001227(transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding);GO:0003690(double-stranded DNA binding);GO:0046332(SMAD binding);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0045637(regulation of myeloid cell differentiation)","NA","NA","NA","purine rich element binding protein B [Source:HGNC Symbol;Acc:HGNC:9702]",{"v":1.982813,"d":"1.98"},{"v":0.657381,"d":"0.66"},{"v":3.01623107452147,"d":"3.02"},{"v":1.59274695821403,"d":"1.59"},{"v":0.0163327765022188,"d":"0.02"},{"v":0.393352766353947,"d":"0.39"},"up","yes"]
["MSTRG.10004","IFNGR2","ENST00000381995;ENST00000290219;ENST00000405436;ENST00000439213;ENST00000545369;ENST00000421802","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005794(Golgi apparatus);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005886(plasma membrane);GO:0000139(Golgi membrane);GO:0030659(cytoplasmic vesicle membrane);GO:0031410(cytoplasmic vesicle);GO:0005887(integral component of plasma membrane);GO:0004920(interleukin-10 receptor activity);GO:0007166(cell surface receptor signaling pathway);GO:0009615(response to virus);GO:0060333(interferon-gamma-mediated signaling pathway);GO:0060334(regulation of interferon-gamma-mediated signaling pathway);GO:0004906(interferon-gamma receptor activity);GO:0051607(defense response to virus);GO:0051607(defense response to virus)","04630(Jak-STAT signaling pathway);04066(HIF-1 signaling pathway);04060(Cytokine-cytokine receptor interaction);04217(Necroptosis);04650(Natural killer cell mediated cytotoxicity);04658(Th1 and Th2 cell differentiation);04659(Th17 cell differentiation);04380(Osteoclast differentiation);05200(Pathways in cancer);05321(Inflammatiory bowel disease (IBD));05132(Salmonella infection);05152(Tuberculosis);05162(Measles);05164(Influenza A);05168(Herpes simplex infection);05145(Toxoplasmosis);05140(Leishmaniasis);05142(Chagas disease (American trypanosomiasis));05142(Chagas disease (American trypanosomiasis))","K05133","NA","interferon gamma receptor 2 [Source:HGNC Symbol;Acc:HGNC:5440]",{"v":16.9125928827703,"d":"16.91"},{"v":52.5144915368243,"d":"52.51"},{"v":0.322055729529645,"d":"0.32"},{"v":-1.63461773648768,"d":"-1.63"},{"v":0.0164168547962412,"d":"0.02"},{"v":0.393352766353947,"d":"0.39"},"down","yes"]
["MSTRG.8787","MXD1;SNRNP27","ENST00000264444;ENST00000244227;ENST00000540449;ENST00000450162;ENST00000435990;ENST00000409442;ENST00000409116;ENST00000410000;ENST00000465446;ENST00000488986;ENST00000487029","GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0046983(protein dimerization activity);GO:0005739(mitochondrion);GO:0005634(nucleus);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:0001078(transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0007275(multicellular organism development);GO:0000790(nuclear chromatin);GO:0003714(transcription corepressor activity);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0008283(cell proliferation);GO:0003712(transcription cofactor activity);GO:0006397(mRNA processing);GO:0008380(RNA splicing);GO:0003676(nucleic acid binding);GO:0008150(biological_process);GO:0005575(cellular_component);GO:0000398(mRNA splicing, via spliceosome);GO:0000398(mRNA splicing, via spliceosome)","03040(Spliceosome);03040(Spliceosome)","K12846","NA","MAX dimerization protein 1 [Source:HGNC Symbol;Acc:HGNC:6761];small nuclear ribonucleoprotein U4/U6.U5 subunit 27 [Source:HGNC Symbol;Acc:HGNC:30240]",{"v":16.4519100790321,"d":"16.45"},{"v":51.0298484726427,"d":"51.03"},{"v":0.322397784266438,"d":"0.32"},{"v":-1.63308626615425,"d":"-1.63"},{"v":0.0164223032784399,"d":"0.02"},{"v":0.393352766353947,"d":"0.39"},"down","yes"]
["ENSG00000009780","FAM76A","ENST00000373949;ENST00000446647;ENST00000373954;ENST00000530324;ENST00000419687;ENST00000010299;ENST00000234549","GO:0005654(nucleoplasm);GO:0005654(nucleoplasm)","NA","NA","NA","family with sequence similarity 76 member A [Source:HGNC Symbol;Acc:HGNC:28530]",{"v":1.52298633886961,"d":"1.52"},{"v":0.494441869856222,"d":"0.49"},{"v":3.08021312861809,"d":"3.08"},{"v":1.62303017850539,"d":"1.62"},{"v":0.0164871387961319,"d":"0.02"},{"v":0.393352766353947,"d":"0.39"},"up","yes"]
["ENSG00000111300","NAA25","ENST00000552527;ENST00000548181;ENST00000548627;ENST00000551858;ENST00000550701;ENST00000547133;ENST00000261745;ENST00000549711","GO:0005737(cytoplasm);GO:0005794(Golgi apparatus);GO:0005829(cytosol);GO:0004596(peptide alpha-N-acetyltransferase activity);GO:0017196(N-terminal peptidyl-methionine acetylation);GO:0031416(NatB complex);GO:0031416(NatB complex)","NA","NA","NA","N(alpha)-acetyltransferase 25, NatB auxiliary subunit [Source:HGNC Symbol;Acc:HGNC:25783]",{"v":0.951949191449447,"d":"0.95"},{"v":0.310402741015008,"d":"0.31"},{"v":3.06681954011295,"d":"3.07"},{"v":1.61674327705691,"d":"1.62"},{"v":0.016489707422026,"d":"0.02"},{"v":0.393352766353947,"d":"0.39"},"up","yes"]
["ENSG00000188785","ZNF548","ENST00000597576;ENST00000600442;ENST00000594693;ENST00000336128;ENST00000598895;ENST00000597047;ENST00000597400;ENST00000602086;ENST00000594668;ENST00000600927;ENST00000596282","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0005622(intracellular);GO:0005622(intracellular)","NA","NA","NA","zinc finger protein 548 [Source:HGNC Symbol;Acc:HGNC:26561]",{"v":0.57890390975491,"d":"0.58"},{"v":0.180282164583671,"d":"0.18"},{"v":3.21109917385219,"d":"3.21"},{"v":1.68306722296317,"d":"1.68"},{"v":0.0164958600738036,"d":"0.02"},{"v":0.393352766353947,"d":"0.39"},"up","yes"]
["MSTRG.12466","GM2A","ENST00000357164;ENST00000523466;ENST00000523004","GO:0008047(enzyme activator activity);GO:0043085(positive regulation of catalytic activity);GO:0006689(ganglioside catabolic process);GO:0016787(hydrolase activity);GO:0006629(lipid metabolic process);GO:0005764(lysosome);GO:0006665(sphingolipid metabolic process);GO:0005576(extracellular region);GO:0006687(glycosphingolipid metabolic process);GO:0070062(extracellular exosome);GO:0043312(neutrophil degranulation);GO:0043202(lysosomal lumen);GO:0035578(azurophil granule lumen);GO:0004563(beta-N-acetylhexosaminidase activity);GO:0005319(lipid transporter activity);GO:0016004(phospholipase activator activity);GO:0030290(sphingolipid activator protein activity);GO:0032428(beta-N-acetylgalactosaminidase activity);GO:0001573(ganglioside metabolic process);GO:0006869(lipid transport);GO:0007611(learning or memory);GO:0009313(oligosaccharide catabolic process);GO:0019915(lipid storage);GO:0050877(neurological system process);GO:0050885(neuromuscular process controlling balance);GO:0051345(positive regulation of hydrolase activity);GO:0005737(cytoplasm);GO:0005739(mitochondrion);GO:0005889(hydrogen:potassium-exchanging ATPase complex);GO:0009898(cytoplasmic side of plasma membrane);GO:0045179(apical cortex);GO:0045179(apical cortex)","04142(Lysosome);04142(Lysosome)","K12383","NA","GM2 ganglioside activator [Source:HGNC Symbol;Acc:HGNC:4367]",{"v":3.19474516633177,"d":"3.19"},{"v":1.05781566220138,"d":"1.06"},{"v":3.02013411267073,"d":"3.02"},{"v":1.5946126155732,"d":"1.59"},{"v":0.0165925912468479,"d":"0.02"},{"v":0.394093046537337,"d":"0.39"},"up","yes"]
["ENSG00000184903","IMMP2L","ENST00000489381;ENST00000405709;ENST00000437687;ENST00000447215;ENST00000331762;ENST00000452753","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016787(hydrolase activity);GO:0005743(mitochondrial inner membrane);GO:0005739(mitochondrion);GO:0008233(peptidase activity);GO:0006508(proteolysis);GO:0008236(serine-type peptidase activity);GO:0001541(ovarian follicle development);GO:0006627(protein processing involved in protein targeting to mitochondrion);GO:0006801(superoxide metabolic process);GO:0006974(cellular response to DNA damage stimulus);GO:0007283(spermatogenesis);GO:0007420(brain development);GO:0008015(blood circulation);GO:0022904(respiratory electron transport chain);GO:0030728(ovulation);GO:0033108(mitochondrial respiratory chain complex assembly);GO:0061300(cerebellum vasculature development);GO:0042720(mitochondrial inner membrane peptidase complex);GO:0006465(signal peptide processing);GO:0006465(signal peptide processing)","03060(Protein export);03060(Protein export)","K09648","EC:3.4.21.-","inner mitochondrial membrane peptidase subunit 2 [Source:HGNC Symbol;Acc:HGNC:14598]",{"v":0.618636068894752,"d":"0.62"},{"v":0.194287372031662,"d":"0.19"},{"v":3.18412906832636,"d":"3.18"},{"v":1.6708988165538,"d":"1.67"},{"v":0.0166223272337652,"d":"0.02"},{"v":0.394093046537337,"d":"0.39"},"up","yes"]
["ENSG00000282961","PRNCR1","ENST00000635449","NA","NA","NA","NA","prostate cancer associated non-coding RNA 1 [Source:HGNC Symbol;Acc:HGNC:48942]",{"v":0.695646,"d":"0.70"},{"v":0.228585,"d":"0.23"},{"v":3.04327055581075,"d":"3.04"},{"v":1.60562259943753,"d":"1.61"},{"v":0.0166250845076372,"d":"0.02"},{"v":0.394093046537337,"d":"0.39"},"up","yes"]
["ENSG00000130338","TULP4","ENST00000367097;ENST00000432358;ENST00000620026;ENST00000367094","GO:0005737(cytoplasm);GO:0016567(protein ubiquitination);GO:0035556(intracellular signal transduction);GO:0005829(cytosol);GO:0043687(post-translational protein modification);GO:0005929(cilium);GO:0035091(phosphatidylinositol binding);GO:0061512(protein localization to cilium);GO:0005622(intracellular);GO:0005622(intracellular)","NA","NA","NA","tubby like protein 4 [Source:HGNC Symbol;Acc:HGNC:15530]",{"v":1.33005635531136,"d":"1.33"},{"v":0.440767743182743,"d":"0.44"},{"v":3.01759004800838,"d":"3.02"},{"v":1.59339682313498,"d":"1.59"},{"v":0.0167388486613418,"d":"0.02"},{"v":0.396010246718816,"d":"0.40"},"up","yes"]
["MSTRG.5572","MMP25","ENST00000336577;ENST00000575441;ENST00000612971;ENST00000570755","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0016787(hydrolase activity);GO:0005886(plasma membrane);GO:0008233(peptidase activity);GO:0006508(proteolysis);GO:0005576(extracellular region);GO:0006954(inflammatory response);GO:0005578(proteinaceous extracellular matrix);GO:0004222(metalloendopeptidase activity);GO:0008237(metallopeptidase activity);GO:0031012(extracellular matrix);GO:0031225(anchored component of membrane);GO:0043312(neutrophil degranulation);GO:0035579(specific granule membrane);GO:0060022(hard palate development);GO:0060022(hard palate development)","NA","NA","NA","matrix metallopeptidase 25 [Source:HGNC Symbol;Acc:HGNC:14246]",{"v":20.3629328012603,"d":"20.36"},{"v":62.8893905688318,"d":"62.89"},{"v":0.323789634739317,"d":"0.32"},{"v":-1.62687129253761,"d":"-1.63"},{"v":0.0168200984974065,"d":"0.02"},{"v":0.396964510673915,"d":"0.40"},"down","yes"]
["MSTRG.1732","JMJD1C","ENST00000542921;MSTRG.1732.1;ENST00000489372;ENST00000467356;ENST00000639129;ENST00000497922;ENST00000399262;ENST00000490669;ENST00000402544;ENST00000469152;ENST00000327520;ENST00000483298;ENST00000633035","GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0016569(covalent chromatin modification);GO:0005515(protein binding);GO:0051213(dioxygenase activity);GO:0005654(nucleoplasm);GO:0005622(intracellular);GO:0000976(transcription regulatory region sequence-specific DNA binding);GO:0007596(blood coagulation);GO:0000785(chromatin);GO:0031490(chromatin DNA binding);GO:0032454(histone demethylase activity (H3-K9 specific));GO:0033169(histone H3-K9 demethylation);GO:0046966(thyroid hormone receptor binding);GO:0046966(thyroid hormone receptor binding)","05202(Transcriptional misregulation in cancers);05202(Transcriptional misregulation in cancers)","K11449","EC:1.14.11.-","jumonji domain containing 1C [Source:HGNC Symbol;Acc:HGNC:12313]",{"v":6.04445574251178,"d":"6.04"},{"v":18.6682881700293,"d":"18.67"},{"v":0.323782003334176,"d":"0.32"},{"v":-1.62690529585,"d":"-1.63"},{"v":0.0168451141799012,"d":"0.02"},{"v":0.396964510673915,"d":"0.40"},"down","yes"]
["MSTRG.5815","AC009133.1","ENST00000569981;ENST00000563806;ENST00000569809;ENST00000569039;ENST00000564980","NA","NA","NA","NA",null,{"v":0.37168440851696,"d":"0.37"},{"v":1.19088889230007,"d":"1.19"},{"v":0.312106705268778,"d":"0.31"},{"v":-1.67988874258346,"d":"-1.68"},{"v":0.0170476162170781,"d":"0.02"},{"v":0.400951942355576,"d":"0.40"},"down","yes"]
["MSTRG.4616","GPR68","ENST00000529300;ENST00000529102;ENST00000531499;ENST00000535815","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0004930(G-protein coupled receptor activity);GO:0007186(G-protein coupled receptor signaling pathway);GO:0005886(plasma membrane);GO:0004871(signal transducer activity);GO:0007165(signal transduction);GO:0005887(integral component of plasma membrane);GO:0006954(inflammatory response);GO:0032024(positive regulation of insulin secretion);GO:0035774(positive regulation of insulin secretion involved in cellular response to glucose stimulus);GO:0045656(negative regulation of monocyte differentiation);GO:0071467(cellular response to pH);GO:2001206(positive regulation of osteoclast development);GO:2001206(positive regulation of osteoclast development)","NA","NA","NA","G protein-coupled receptor 68 [Source:HGNC Symbol;Acc:HGNC:4519]",{"v":0.484612348993289,"d":"0.48"},{"v":1.5470688004881,"d":"1.55"},{"v":0.313245505849768,"d":"0.31"},{"v":-1.67463428361561,"d":"-1.67"},{"v":0.0170861471918668,"d":"0.02"},{"v":0.401074823556452,"d":"0.40"},"down","yes"]
["MSTRG.9647","COMMD7","ENST00000278980;ENST00000474815;ENST00000610160;ENST00000446419","GO:0043231(intracellular membrane-bounded organelle);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0005515(protein binding);GO:0031410(cytoplasmic vesicle);GO:0070062(extracellular exosome);GO:0032088(negative regulation of NF-kappaB transcription factor activity);GO:0045892(negative regulation of transcription, DNA-templated);GO:0033209(tumor necrosis factor-mediated signaling pathway);GO:0051059(NF-kappaB binding);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016021(integral component of membrane)","NA","NA","NA","COMM domain containing 7 [Source:HGNC Symbol;Acc:HGNC:16223]",{"v":1.8138461122291,"d":"1.81"},{"v":5.63943236571207,"d":"5.64"},{"v":0.321636291492268,"d":"0.32"},{"v":-1.63649789421021,"d":"-1.64"},{"v":0.0172312487457348,"d":"0.02"},{"v":0.403693963805717,"d":"0.40"},"down","yes"]
["MSTRG.13775","STEAP4","ENST00000380079;MSTRG.13775.2;ENST00000414498;ENST00000301959","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005794(Golgi apparatus);GO:0046872(metal ion binding);GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0006811(ion transport);GO:0005886(plasma membrane);GO:0000139(Golgi membrane);GO:0005887(integral component of plasma membrane);GO:0070062(extracellular exosome);GO:0045444(fat cell differentiation);GO:0005768(endosome);GO:0055072(iron ion homeostasis);GO:0008823(cupric reductase activity);GO:0052851(ferric-chelate reductase (NADPH) activity);GO:0015677(copper ion import);GO:0098706(ferric iron import across plasma membrane);GO:0098706(ferric iron import across plasma membrane)","NA","NA","NA","STEAP4 metalloreductase [Source:HGNC Symbol;Acc:HGNC:21923]",{"v":3.44315990772513,"d":"3.44"},{"v":10.5786599153703,"d":"10.58"},{"v":0.325481671144601,"d":"0.33"},{"v":-1.61935179172169,"d":"-1.62"},{"v":0.0173961114977004,"d":"0.02"},{"v":0.406764999330696,"d":"0.41"},"down","yes"]
["MSTRG.4882","KATNBL1","ENST00000256544;ENST00000559760;ENST00000560915;ENST00000560247;ENST00000558473;ENST00000559462;ENST00000560308;ENST00000560310;ENST00000560108;ENST00000558681;ENST00000561270;ENST00000561371;ENST00000557877;ENST00000560671;ENST00000540594;ENST00000559515","GO:0005515(protein binding);GO:0005730(nucleolus);GO:0005730(nucleolus)","NA","NA","NA","katanin regulatory subunit B1 like 1 [Source:HGNC Symbol;Acc:HGNC:26199]",{"v":0.605078300095746,"d":"0.61"},{"v":1.8832850711257,"d":"1.88"},{"v":0.321288746654839,"d":"0.32"},{"v":-1.63805764451556,"d":"-1.64"},{"v":0.0175431158972733,"d":"0.02"},{"v":0.409407367509623,"d":"0.41"},"down","yes"]
["MSTRG.3589","LIN7A","ENST00000552864;ENST00000552093;ENST00000549417;ENST00000261203","GO:0006810(transport);GO:0016020(membrane);GO:0015031(protein transport);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0030054(cell junction);GO:0045202(synapse);GO:0045211(postsynaptic membrane);GO:0098793(presynapse);GO:0005923(bicellular tight junction);GO:0006887(exocytosis);GO:0070062(extracellular exosome);GO:0045199(maintenance of epithelial cell apical/basal polarity);GO:0016323(basolateral plasma membrane);GO:0005911(cell-cell junction);GO:0014069(postsynaptic density);GO:0043005(neuron projection);GO:0006461(protein complex assembly);GO:0007269(neurotransmitter secretion);GO:0097016(L27 domain binding);GO:0048489(synaptic vesicle transport);GO:0048839(inner ear development);GO:1903361(protein localization to basolateral plasma membrane);GO:0097025(MPP7-DLG1-LIN7 complex);GO:0097025(MPP7-DLG1-LIN7 complex)","NA","NA","NA","lin-7 homolog A, crumbs cell polarity complex component [Source:HGNC Symbol;Acc:HGNC:17787]",{"v":1.99809120323767,"d":"2.00"},{"v":6.13300143296542,"d":"6.13"},{"v":0.325793369702762,"d":"0.33"},{"v":-1.61797085135014,"d":"-1.62"},{"v":0.0177761936795652,"d":"0.02"},{"v":0.413443873787724,"d":"0.41"},"down","yes"]
["MSTRG.4593","FOXN3;EFCAB11","MSTRG.4593.3;ENST00000345097;ENST00000557258;ENST00000553840;ENST00000555353;ENST00000557718;ENST00000555872;ENST00000261302;ENST00000555430;ENST00000555855;ENST00000557261;ENST00000553353;ENST00000538485;ENST00000556609;ENST00000554761;ENST00000556916;ENST00000615335;ENST00000554005;ENST00000555658;ENST00000557496;ENST00000556541;ENST00000557572;ENST00000316738;ENST00000555034","GO:0005634(nucleus);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0043565(sequence-specific DNA binding);GO:0005515(protein binding);GO:0007049(cell cycle);GO:0097094(craniofacial suture morphogenesis);GO:0030154(cell differentiation);GO:0008022(protein C-terminus binding);GO:0045892(negative regulation of transcription, DNA-templated);GO:0045893(positive regulation of transcription, DNA-templated);GO:0007095(mitotic G2 DNA damage checkpoint);GO:0046872(metal ion binding);GO:0005509(calcium ion binding);GO:0007095(mitotic G2 DNA damage checkpoint)","NA","NA","NA","forkhead box N3 [Source:HGNC Symbol;Acc:HGNC:1928];EF-hand calcium binding domain 11 [Source:HGNC Symbol;Acc:HGNC:20357]",{"v":1.34712976105508,"d":"1.35"},{"v":4.13731737243341,"d":"4.14"},{"v":0.325604646631871,"d":"0.33"},{"v":-1.61880680675457,"d":"-1.62"},{"v":0.017784747269726,"d":"0.02"},{"v":0.413443873787724,"d":"0.41"},"down","yes"]
["MSTRG.12509","ADAM19","ENST00000257527;MSTRG.12509.4;ENST00000519752;ENST00000517951;ENST00000517905;ENST00000517374","GO:0016021(integral component of membrane);GO:0017124(SH3 domain binding);GO:0006508(proteolysis);GO:0005794(Golgi apparatus);GO:0004222(metalloendopeptidase activity);GO:0008237(metallopeptidase activity);GO:0006509(membrane protein ectodomain proteolysis);GO:0016020(membrane);GO:0046872(metal ion binding);GO:0016787(hydrolase activity);GO:0008233(peptidase activity);GO:0005886(plasma membrane);GO:0030198(extracellular matrix organization);GO:0007507(heart development);GO:0007507(heart development)","NA","NA","NA","ADAM metallopeptidase domain 19 [Source:HGNC Symbol;Acc:HGNC:197]",{"v":4.82158963164704,"d":"4.82"},{"v":14.757926709018,"d":"14.76"},{"v":0.326711856395164,"d":"0.33"},{"v":-1.61390928366165,"d":"-1.61"},{"v":0.0178356396610148,"d":"0.02"},{"v":0.413828078608747,"d":"0.41"},"down","yes"]
["MSTRG.13723","HIP1","MSTRG.13723.1;ENST00000336926;ENST00000479835;ENST00000434438;ENST00000420909;ENST00000616821;ENST00000404944","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0043231(intracellular membrane-bounded organelle);GO:0003779(actin binding);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0006897(endocytosis);GO:0006915(apoptotic process);GO:0005515(protein binding);GO:0007010(cytoskeleton organization);GO:0030154(cell differentiation);GO:0031410(cytoplasmic vesicle);GO:0005543(phospholipid binding);GO:0030276(clathrin binding);GO:0048268(clathrin coat assembly);GO:0030136(clathrin-coated vesicle);GO:0035091(phosphatidylinositol binding);GO:0072583(clathrin-dependent endocytosis);GO:0005829(cytosol);GO:0061024(membrane organization);GO:0012505(endomembrane system);GO:0030665(clathrin-coated vesicle membrane);GO:0030122(AP-2 adaptor complex);GO:0005154(epidermal growth factor receptor binding);GO:0005200(structural constituent of cytoskeleton);GO:0032051(clathrin light chain binding);GO:0032266(phosphatidylinositol-3-phosphate binding);GO:0035254(glutamate receptor binding);GO:0035612(AP-2 adaptor complex binding);GO:0035615(clathrin adaptor activity);GO:0042803(protein homodimerization activity);GO:0043325(phosphatidylinositol-3,4-bisphosphate binding);GO:0046982(protein heterodimerization activity);GO:0051015(actin filament binding);GO:0080025(phosphatidylinositol-3,5-bisphosphate binding);GO:0006919(activation of cysteine-type endopeptidase activity involved in apoptotic process);GO:0030100(regulation of endocytosis);GO:0042981(regulation of apoptotic process);GO:0045742(positive regulation of epidermal growth factor receptor signaling pathway);GO:0048260(positive regulation of receptor-mediated endocytosis);GO:0050821(protein stabilization);GO:0051897(positive regulation of protein kinase B signaling);GO:0097190(apoptotic signaling pathway);GO:0099637(neurotransmitter receptor transport);GO:2000588(positive regulation of platelet-derived growth factor receptor-beta signaling pathway);GO:0005794(Golgi apparatus);GO:0005856(cytoskeleton);GO:0031234(extrinsic component of cytoplasmic side of plasma membrane);GO:0098793(presynapse);GO:0098794(postsynapse);GO:0098888(extrinsic component of presynaptic membrane);GO:0098890(extrinsic component of postsynaptic membrane);GO:0098890(extrinsic component of postsynaptic membrane)","05016(Huntington's disease);05016(Huntington's disease)","K04559","NA","huntingtin interacting protein 1 [Source:HGNC Symbol;Acc:HGNC:4913]",{"v":2.01553967462941,"d":"2.02"},{"v":6.16731246848672,"d":"6.17"},{"v":0.326810046503767,"d":"0.33"},{"v":-1.61347576067433,"d":"-1.61"},{"v":0.0179917745783905,"d":"0.02"},{"v":0.416647979755727,"d":"0.42"},"down","yes"]
["ENSG00000133687","TMTC1","ENST00000256062;ENST00000546582;ENST00000553189;ENST00000551659","GO:0006396(RNA processing);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005739(mitochondrion);GO:0005739(mitochondrion)","NA","NA","NA","transmembrane and tetratricopeptide repeat containing 1 [Source:HGNC Symbol;Acc:HGNC:24099]",{"v":0.379198634599617,"d":"0.38"},{"v":1.1720389991801,"d":"1.17"},{"v":0.323537557082047,"d":"0.32"},{"v":-1.62799490115174,"d":"-1.63"},{"v":0.0180873159988152,"d":"0.02"},{"v":0.418056543680869,"d":"0.42"},"down","yes"]
["ENSG00000184441","AP001062.1","ENST00000448927","NA","NA","NA","NA",null,{"v":1.366012,"d":"1.37"},{"v":0.453828,"d":"0.45"},{"v":3.00997734824647,"d":"3.01"},{"v":1.5897526299433,"d":"1.59"},{"v":0.0181885038694378,"d":"0.02"},{"v":0.419589968574272,"d":"0.42"},"up","yes"]
["ENSG00000064225","ST3GAL6","ENST00000485391;ENST00000474595;ENST00000477574;ENST00000485145;ENST00000489112;ENST00000469105;ENST00000476833;ENST00000460774;ENST00000265261;ENST00000468553;ENST00000497008;ENST00000477899;ENST00000486334;ENST00000497621;ENST00000490684;ENST00000462152;ENST00000492254;ENST00000483910;ENST00000466482;ENST00000493953;ENST00000495376;ENST00000394162","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016740(transferase activity);GO:0008373(sialyltransferase activity);GO:0016757(transferase activity, transferring glycosyl groups);GO:0006486(protein glycosylation);GO:0097503(sialylation);GO:0005794(Golgi apparatus);GO:0000139(Golgi membrane);GO:0070062(extracellular exosome);GO:0006464(cellular protein modification process);GO:0018146(keratan sulfate biosynthetic process);GO:0009311(oligosaccharide metabolic process);GO:0071354(cellular response to interleukin-6);GO:0003836(beta-galactoside (CMP) alpha-2,3-sialyltransferase activity);GO:0018279(protein N-linked glycosylation via asparagine);GO:0052798(beta-galactoside alpha-2,3-sialyltransferase activity);GO:0006664(glycolipid metabolic process);GO:0006664(glycolipid metabolic process)","00601(Glycosphingolipid biosynthesis - lacto and neolacto series);00601(Glycosphingolipid biosynthesis - lacto and neolacto series)","K03792","EC:2.4.99.6","ST3 beta-galactoside alpha-2,3-sialyltransferase 6 [Source:HGNC Symbol;Acc:HGNC:18080]",{"v":0.433849805184478,"d":"0.43"},{"v":1.34573649395674,"d":"1.35"},{"v":0.322388377763964,"d":"0.32"},{"v":-1.63312835984445,"d":"-1.63"},{"v":0.0182243228263175,"d":"0.02"},{"v":0.419612419645346,"d":"0.42"},"down","yes"]
["MSTRG.2649","AP002387.1","ENST00000529369","NA","NA","NA","NA",null,{"v":5.683285,"d":"5.68"},{"v":1.872625,"d":"1.87"},{"v":3.03492957746479,"d":"3.03"},{"v":1.60166304055969,"d":"1.60"},{"v":0.0183799314602332,"d":"0.02"},{"v":0.421691513597543,"d":"0.42"},"up","yes"]
["MSTRG.1899","UBTD1","ENST00000370664","GO:0005515(protein binding);GO:0043130(ubiquitin binding)","NA","NA","NA","ubiquitin domain containing 1 [Source:HGNC Symbol;Acc:HGNC:25683]",{"v":1.908996,"d":"1.91"},{"v":5.886263,"d":"5.89"},{"v":0.324313745410288,"d":"0.32"},{"v":-1.62453792396131,"d":"-1.62"},{"v":0.0184068437961456,"d":"0.02"},{"v":0.421691513597543,"d":"0.42"},"down","yes"]
["MSTRG.1114","SLAMF6","ENST00000368059;ENST00000368057;ENST00000368055","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005886(plasma membrane);GO:0002376(immune system process);GO:0045087(innate immune response);GO:0002250(adaptive immune response);GO:0050776(regulation of immune response);GO:0005515(protein binding);GO:0070062(extracellular exosome);GO:0045954(positive regulation of natural killer cell mediated cytotoxicity);GO:0032729(positive regulation of interferon-gamma production);GO:0072540(T-helper 17 cell lineage commitment);GO:0032740(positive regulation of interleukin-17 production);GO:0001779(natural killer cell differentiation);GO:0001787(natural killer cell proliferation);GO:0001787(natural killer cell proliferation)","NA","NA","NA","SLAM family member 6 [Source:HGNC Symbol;Acc:HGNC:21392]",{"v":18.18533649126,"d":"18.19"},{"v":6.19046504770575,"d":"6.19"},{"v":2.93763656706206,"d":"2.94"},{"v":1.55465592233071,"d":"1.55"},{"v":0.0184196758140099,"d":"0.02"},{"v":0.421691513597543,"d":"0.42"},"up","yes"]
["MSTRG.5973","RPS27AP16","ENST00000591758","NA","NA","NA","NA","ribosomal protein S27a pseudogene 16 [Source:HGNC Symbol;Acc:HGNC:36855]",{"v":5.11538,"d":"5.12"},{"v":15.804424,"d":"15.80"},{"v":0.323667600919844,"d":"0.32"},{"v":-1.62741513567832,"d":"-1.63"},{"v":0.0184801894358652,"d":"0.02"},{"v":0.422274081948177,"d":"0.42"},"down","yes"]
["ENSG00000138738","PRDM5","ENST00000264808;ENST00000394435;ENST00000512845;ENST00000505484","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0005730(nucleolus);GO:0008168(methyltransferase activity);GO:0016740(transferase activity);GO:0032259(methylation);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0016569(covalent chromatin modification);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0016604(nuclear body);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:0001078(transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0043565(sequence-specific DNA binding);GO:0044212(transcription regulatory region DNA binding);GO:0045892(negative regulation of transcription, DNA-templated);GO:0070491(repressing transcription factor binding);GO:0000278(mitotic cell cycle);GO:0016575(histone deacetylation);GO:0051567(histone H3-K9 methylation);GO:1990830(cellular response to leukemia inhibitory factor);GO:1990830(cellular response to leukemia inhibitory factor)","NA","NA","NA","PR/SET domain 5 [Source:HGNC Symbol;Acc:HGNC:9349]",{"v":0.157244584743091,"d":"0.16"},{"v":0.502158101502574,"d":"0.50"},{"v":0.313137604018692,"d":"0.31"},{"v":-1.67513132587516,"d":"-1.68"},{"v":0.0185383854170648,"d":"0.02"},{"v":0.422801585591467,"d":"0.42"},"down","yes"]
["MSTRG.12984","SRPK1","ENST00000508473;ENST00000423325;ENST00000373825;ENST00000513367;ENST00000505885;ENST00000361690;ENST00000346162;ENST00000507292;ENST00000502969;ENST00000507909","GO:0003723(RNA binding);GO:0006397(mRNA processing);GO:0008380(RNA splicing);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0005829(cytosol);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0005886(plasma membrane);GO:0005783(endoplasmic reticulum);GO:0005515(protein binding);GO:0000287(magnesium ion binding);GO:0030154(cell differentiation);GO:0007059(chromosome segregation);GO:0043231(intracellular membrane-bounded organelle);GO:0016032(viral process);GO:0045087(innate immune response);GO:0016363(nuclear matrix);GO:0045070(positive regulation of viral genome replication);GO:0035556(intracellular signal transduction);GO:0048024(regulation of mRNA splicing, via spliceosome);GO:0000245(spliceosomal complex assembly);GO:0045071(negative regulation of viral genome replication);GO:0050684(regulation of mRNA processing);GO:0035092(sperm chromatin condensation);GO:0035092(sperm chromatin condensation)","05168(Herpes simplex infection);05168(Herpes simplex infection)","K15409","EC:2.7.11.1","SRSF protein kinase 1 [Source:HGNC Symbol;Acc:HGNC:11305]",{"v":1.69180868245666,"d":"1.69"},{"v":5.15771851688583,"d":"5.16"},{"v":0.328014930810562,"d":"0.33"},{"v":-1.60816660895834,"d":"-1.61"},{"v":0.0186354416759219,"d":"0.02"},{"v":0.423897119568456,"d":"0.42"},"down","yes"]
["MSTRG.8972","CIAO1","MSTRG.8972.5;ENST00000488633;ENST00000272402;ENST00000491394;ENST00000469320","GO:0005515(protein binding);GO:0016226(iron-sulfur cluster assembly);GO:0007059(chromosome segregation);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0008284(positive regulation of cell proliferation);GO:0071817(MMXD complex);GO:0097361(CIA complex);GO:0097361(CIA complex)","NA","NA","NA","cytosolic iron-sulfur assembly component 1 [Source:HGNC Symbol;Acc:HGNC:14280]",{"v":8.56097958571074,"d":"8.56"},{"v":2.91791405432895,"d":"2.92"},{"v":2.93393822652517,"d":"2.93"},{"v":1.55283849567933,"d":"1.55"},{"v":0.0186568238972996,"d":"0.02"},{"v":0.423897119568456,"d":"0.42"},"up","yes"]
["MSTRG.15481","CD99L2","ENST00000370377;ENST00000491877;ENST00000355149;ENST00000466436;ENST00000418547;ENST00000634795;ENST00000437787;ENST00000346693;ENST00000613030","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0007155(cell adhesion);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0030054(cell junction);GO:0005925(focal adhesion);GO:0005925(focal adhesion)","NA","NA","NA","CD99 molecule like 2 [Source:HGNC Symbol;Acc:HGNC:18237]",{"v":1.24369046077751,"d":"1.24"},{"v":3.81118307445332,"d":"3.81"},{"v":0.326326612099553,"d":"0.33"},{"v":-1.6156114501529,"d":"-1.62"},{"v":0.018757130994172,"d":"0.02"},{"v":0.425373580850884,"d":"0.43"},"down","yes"]
["MSTRG.10645","VHL","ENST00000256474;ENST00000477538;ENST00000345392","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005654(nucleoplasm);GO:0016567(protein ubiquitination);GO:0005783(endoplasmic reticulum);GO:0005739(mitochondrion);GO:0005515(protein binding);GO:0045893(positive regulation of transcription, DNA-templated);GO:0005829(cytosol);GO:0050821(protein stabilization);GO:0043687(post-translational protein modification);GO:0061418(regulation of transcription from RNA polymerase II promoter in response to hypoxia);GO:0043066(negative regulation of apoptotic process);GO:0008134(transcription factor binding);GO:0019899(enzyme binding);GO:0045597(positive regulation of cell differentiation);GO:0008285(negative regulation of cell proliferation);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0004842(ubiquitin-protein transferase activity);GO:0061630(ubiquitin protein ligase activity);GO:0006508(proteolysis);GO:0006355(regulation of transcription, DNA-templated);GO:0000902(cell morphogenesis);GO:0010629(negative regulation of gene expression);GO:0046426(negative regulation of JAK-STAT cascade);GO:0061428(negative regulation of transcription from RNA polymerase II promoter in response to hypoxia);GO:0030891(VCB complex);GO:0030891(VCB complex)","04120(Ubiquitin mediated proteolysis);04066(HIF-1 signaling pathway);05200(Pathways in cancer);05211(Renal cell carcinoma);05211(Renal cell carcinoma)","K03871","NA","von Hippel-Lindau tumor suppressor [Source:HGNC Symbol;Acc:HGNC:12687]",{"v":1.67071250581533,"d":"1.67"},{"v":5.08627547495846,"d":"5.09"},{"v":0.328474640046698,"d":"0.33"},{"v":-1.60614610361273,"d":"-1.61"},{"v":0.0189581170410263,"d":"0.02"},{"v":0.428550489948747,"d":"0.43"},"down","yes"]
["MSTRG.8818","DYSF","ENST00000409582;ENST00000409762;ENST00000409651;ENST00000413539;ENST00000410020;ENST00000410041;ENST00000409366;ENST00000479049;ENST00000468173;ENST00000394120;ENST00000429174;ENST00000258104;ENST00000493767;ENST00000472873;ENST00000409744;ENST00000475076;ENST00000494501;ENST00000461565;ENST00000487180","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0046872(metal ion binding);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0005815(microtubule organizing center);GO:0030659(cytoplasmic vesicle membrane);GO:0031410(cytoplasmic vesicle);GO:0005544(calcium-dependent phospholipid binding);GO:0005509(calcium ion binding);GO:0008289(lipid binding);GO:0005768(endosome);GO:0070062(extracellular exosome);GO:0042383(sarcolemma);GO:0005769(early endosome);GO:0005770(late endosome);GO:0030315(T-tubule);GO:0005543(phospholipid binding);GO:0006936(muscle contraction);GO:0030139(endocytic vesicle);GO:0001778(plasma membrane repair);GO:0006906(vesicle fusion);GO:0030027(lamellipodium);GO:0030027(lamellipodium)","NA","NA","NA","dysferlin [Source:HGNC Symbol;Acc:HGNC:3097]",{"v":6.68719815907465,"d":"6.69"},{"v":20.2263324540901,"d":"20.23"},{"v":0.330618423990276,"d":"0.33"},{"v":-1.59676097262014,"d":"-1.60"},{"v":0.0189683948798109,"d":"0.02"},{"v":0.428550489948747,"d":"0.43"},"down","yes"]
["MSTRG.494","HYI","ENST00000486909;ENST00000372434;ENST00000372425;ENST00000372427;ENST00000372433;ENST00000483618;ENST00000372430;ENST00000496142;ENST00000583037;ENST00000372432","GO:0016853(isomerase activity);GO:0008903(hydroxypyruvate isomerase activity);GO:0005515(protein binding);GO:0003674(molecular_function);GO:0008150(biological_process);GO:0005575(cellular_component);GO:0005575(cellular_component)","00630(Glyoxylate and dicarboxylate metabolism);00630(Glyoxylate and dicarboxylate metabolism)","K01816","EC:5.3.1.22","hydroxypyruvate isomerase (putative) [Source:HGNC Symbol;Acc:HGNC:26948]",{"v":0.999034558759124,"d":"1.00"},{"v":0.312938175182482,"d":"0.31"},{"v":3.19243428251143,"d":"3.19"},{"v":1.67465692180092,"d":"1.67"},{"v":0.0190209977345504,"d":"0.02"},{"v":0.428934184867894,"d":"0.43"},"up","yes"]
["ENSG00000163430","FSTL1","ENST00000295633;ENST00000469005;ENST00000467994;ENST00000488318;ENST00000464690","GO:0005509(calcium ion binding);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0005615(extracellular space);GO:0008201(heparin binding);GO:0070062(extracellular exosome);GO:0044267(cellular protein metabolic process);GO:0043687(post-translational protein modification);GO:0030509(BMP signaling pathway);GO:0005788(endoplasmic reticulum lumen);GO:0042594(response to starvation);GO:0042594(response to starvation)","NA","NA","NA","follistatin like 1 [Source:HGNC Symbol;Acc:HGNC:3972]",{"v":0.109212532714564,"d":"0.11"},{"v":0.352546014323364,"d":"0.35"},{"v":0.309782349757021,"d":"0.31"},{"v":-1.69067314780127,"d":"-1.69"},{"v":0.0193213316753575,"d":"0.02"},{"v":0.434892478569449,"d":"0.43"},"down","yes"]
["ENSG00000175274","TP53I11","ENST00000525680;ENST00000525145;ENST00000532921;ENST00000531130;ENST00000527685;ENST00000354556;ENST00000533443;ENST00000308212;ENST00000533937;ENST00000532253;ENST00000616990;ENST00000530035;ENST00000531928;ENST00000524774;ENST00000525683;ENST00000533940;ENST00000525667;ENST00000395648;ENST00000528473","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0006950(response to stress);GO:0008285(negative regulation of cell proliferation);GO:0008285(negative regulation of cell proliferation)","NA","NA","NA","tumor protein p53 inducible protein 11 [Source:HGNC Symbol;Acc:HGNC:16842]",{"v":0.366644975765827,"d":"0.37"},{"v":1.13738339346494,"d":"1.14"},{"v":0.322358298769314,"d":"0.32"},{"v":-1.63326297028302,"d":"-1.63"},{"v":0.0194237004205771,"d":"0.02"},{"v":0.436380971016026,"d":"0.44"},"down","yes"]
["MSTRG.3161","CLEC12B","ENST00000544853;ENST00000535903;ENST00000396502;ENST00000338896;ENST00000539155","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0030246(carbohydrate binding);GO:0005886(plasma membrane);GO:0043234(protein complex);GO:0045953(negative regulation of natural killer cell mediated cytotoxicity);GO:0019903(protein phosphatase binding);GO:0009897(external side of plasma membrane);GO:0002769(natural killer cell inhibitory signaling pathway);GO:0030547(receptor inhibitor activity);GO:2000272(negative regulation of receptor activity);GO:2000272(negative regulation of receptor activity)","NA","NA","NA","C-type lectin domain family 12 member B [Source:HGNC Symbol;Acc:HGNC:31966]",{"v":0.167748422961549,"d":"0.17"},{"v":0.541913539132806,"d":"0.54"},{"v":0.309548315087288,"d":"0.31"},{"v":-1.6917634883662,"d":"-1.69"},{"v":0.0194651704214105,"d":"0.02"},{"v":0.436498290902468,"d":"0.44"},"down","yes"]
["MSTRG.11142","HACD2","ENST00000383657;ENST00000469317;ENST00000471236;ENST00000480081;ENST00000493515","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016829(lyase activity);GO:0006629(lipid metabolic process);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0006631(fatty acid metabolic process);GO:0006633(fatty acid biosynthetic process);GO:0042761(very long-chain fatty acid biosynthetic process);GO:0005515(protein binding);GO:0035338(long-chain fatty-acyl-CoA biosynthetic process);GO:0030176(integral component of endoplasmic reticulum membrane);GO:0080023(3R-hydroxyacyl-CoA dehydratase activity);GO:0102343(3-hydroxy-arachidoyl-CoA dehydratase activity);GO:0102344(3-hydroxy-behenoyl-CoA dehydratase activity);GO:0102345(3-hydroxy-lignoceroyl-CoA dehydratase activity);GO:0019899(enzyme binding);GO:0030148(sphingolipid biosynthetic process);GO:0018812(3-hydroxyacyl-CoA dehydratase activity);GO:0030497(fatty acid elongation);GO:0030497(fatty acid elongation)","00062(Fatty acid elongation);01040(Biosynthesis of unsaturated fatty acids);01040(Biosynthesis of unsaturated fatty acids)","K10703","EC:4.2.1.134","3-hydroxyacyl-CoA dehydratase 2 [Source:HGNC Symbol;Acc:HGNC:9640]",{"v":0.891858840403663,"d":"0.89"},{"v":2.71976833451691,"d":"2.72"},{"v":0.327917208640521,"d":"0.33"},{"v":-1.60859648053397,"d":"-1.61"},{"v":0.0195179739413586,"d":"0.02"},{"v":0.436868851676282,"d":"0.44"},"down","yes"]
["ENSG00000163625","WDFY3","ENST00000295888;ENST00000509825;ENST00000505923;ENST00000514711;ENST00000514071;ENST00000504990;ENST00000425179;ENST00000502713;ENST00000512267;ENST00000509172;ENST00000426414","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0046872(metal ion binding);GO:0005730(nucleolus);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0006914(autophagy);GO:0003831(beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity);GO:0097635(extrinsic component of autophagosome membrane);GO:0005776(autophagosome);GO:0031965(nuclear membrane);GO:0005635(nuclear envelope);GO:0016605(PML body);GO:0016234(inclusion body);GO:0034274(Atg12-Atg5-Atg16 complex);GO:0005545(1-phosphatidylinositol binding);GO:0035973(aggrephagy);GO:0019898(extrinsic component of membrane);GO:0019898(extrinsic component of membrane)","NA","NA","NA","WD repeat and FYVE domain containing 3 [Source:HGNC Symbol;Acc:HGNC:20751]",{"v":1.20910681217371,"d":"1.21"},{"v":3.6405112372449,"d":"3.64"},{"v":0.332125554181437,"d":"0.33"},{"v":-1.5901993649028,"d":"-1.59"},{"v":0.0196254728788606,"d":"0.02"},{"v":0.438187147935568,"d":"0.44"},"down","yes"]
["ENSG00000264247","LINC00909","ENST00000580048;ENST00000581192","NA","NA","NA","NA","long intergenic non-protein coding RNA 909 [Source:HGNC Symbol;Acc:HGNC:44331]",{"v":0.328761043292357,"d":"0.33"},{"v":1.02539966755746,"d":"1.03"},{"v":0.320617466236826,"d":"0.32"},{"v":-1.64107507374027,"d":"-1.64"},{"v":0.0196954496835334,"d":"0.02"},{"v":0.438187147935568,"d":"0.44"},"down","yes"]
["ENSG00000125375","ATP5S","ENST00000556962;ENST00000358473;ENST00000557421;ENST00000554438;ENST00000554951;ENST00000555939;ENST00000311459;ENST00000554204;ENST00000553774;ENST00000426751","GO:0006810(transport);GO:0016020(membrane);GO:0046872(metal ion binding);GO:0005743(mitochondrial inner membrane);GO:0005739(mitochondrion);GO:0006811(ion transport);GO:0015992(proton transport);GO:0006754(ATP biosynthetic process);GO:0042407(cristae formation);GO:0042776(mitochondrial ATP synthesis coupled proton transport);GO:0045263(proton-transporting ATP synthase complex, coupling factor F(o));GO:0015078(hydrogen ion transmembrane transporter activity);GO:0015078(hydrogen ion transmembrane transporter activity)","NA","NA","NA","ATP synthase, H+ transporting, mitochondrial Fo complex subunit s (factor B) [Source:HGNC Symbol;Acc:HGNC:18799]",{"v":0.204059300964858,"d":"0.20"},{"v":0.63134800380632,"d":"0.63"},{"v":0.323212079130067,"d":"0.32"},{"v":-1.62944697917572,"d":"-1.63"},{"v":0.0197113796581101,"d":"0.02"},{"v":0.438187147935568,"d":"0.44"},"down","yes"]
["MSTRG.2877","MPZL3","ENST00000278949;ENST00000446386;ENST00000527472","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0007155(cell adhesion);GO:0005515(protein binding);GO:0030198(extracellular matrix organization);GO:0042633(hair cycle);GO:0042633(hair cycle)","NA","NA","NA","myelin protein zero like 3 [Source:HGNC Symbol;Acc:HGNC:27279]",{"v":4.632481,"d":"4.63"},{"v":13.9402904334677,"d":"13.94"},{"v":0.332308786686279,"d":"0.33"},{"v":-1.58940365457747,"d":"-1.59"},{"v":0.0197224243631521,"d":"0.02"},{"v":0.438187147935568,"d":"0.44"},"down","yes"]
["MSTRG.6199","CRISPLD2","ENST00000567845;ENST00000262424;ENST00000566151;ENST00000569090;ENST00000566789;ENST00000569262;ENST00000565561;ENST00000566165;ENST00000564567","GO:0005576(extracellular region);GO:0005539(glycosaminoglycan binding);GO:0008201(heparin binding);GO:0030198(extracellular matrix organization);GO:0030324(lung development);GO:0005578(proteinaceous extracellular matrix);GO:0070062(extracellular exosome);GO:0043312(neutrophil degranulation);GO:0034774(secretory granule lumen);GO:1904813(ficolin-1-rich granule lumen);GO:0060325(face morphogenesis);GO:0030133(transport vesicle);GO:0030133(transport vesicle)","NA","NA","NA","cysteine rich secretory protein LCCL domain containing 2 [Source:HGNC Symbol;Acc:HGNC:25248]",{"v":3.09097675530446,"d":"3.09"},{"v":9.28933617074702,"d":"9.29"},{"v":0.332744633038282,"d":"0.33"},{"v":-1.58751269832645,"d":"-1.59"},{"v":0.0198593521349598,"d":"0.02"},{"v":0.44014361998265,"d":"0.44"},"down","yes"]
["MSTRG.13045","CNPY3;AL035587.1","MSTRG.13045.1;ENST00000372836;ENST00000450671;MSTRG.13045.3;ENST00000607218;ENST00000394142","GO:0005783(endoplasmic reticulum);GO:0002376(immune system process);GO:0045087(innate immune response);GO:0002224(toll-like receptor signaling pathway);GO:0005788(endoplasmic reticulum lumen);GO:0005102(receptor binding);GO:0005102(receptor binding)","NA","NA","NA","canopy FGF signaling regulator 3 [Source:HGNC Symbol;Acc:HGNC:11968]",{"v":9.9347489342382,"d":"9.93"},{"v":29.7983286323839,"d":"29.80"},{"v":0.333399535819651,"d":"0.33"},{"v":-1.58467599917477,"d":"-1.58"},{"v":0.019891419965908,"d":"0.02"},{"v":0.44014361998265,"d":"0.44"},"down","yes"]
["MSTRG.1363","CD46","ENST00000469535;ENST00000367041;ENST00000357714;ENST00000480003;ENST00000367042;ENST00000354848;ENST00000322875;ENST00000462968;ENST00000322918;ENST00000360212;ENST00000488596;ENST00000636114;ENST00000496723;ENST00000490278;ENST00000464082;ENST00000358170;ENST00000493796;ENST00000471987","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0043086(negative regulation of catalytic activity);GO:0031410(cytoplasmic vesicle);GO:0009986(cell surface);GO:0002376(immune system process);GO:0045087(innate immune response);GO:0005925(focal adhesion);GO:0002250(adaptive immune response);GO:0030449(regulation of complement activation);GO:0046718(viral entry into host cell);GO:0070062(extracellular exosome);GO:0010628(positive regulation of gene expression);GO:0042102(positive regulation of T cell proliferation);GO:0007338(single fertilization);GO:0016032(viral process);GO:0005887(integral component of plasma membrane);GO:0002456(T cell mediated immunity);GO:0010629(negative regulation of gene expression);GO:0071636(positive regulation of transforming growth factor beta production);GO:0006958(complement activation, classical pathway);GO:0004872(receptor activity);GO:0045296(cadherin binding);GO:0001618(virus receptor activity);GO:0032733(positive regulation of interleukin-10 production);GO:0008593(regulation of Notch signaling pathway);GO:0032613(interleukin-10 production);GO:0035581(sequestering of extracellular ligand from receptor);GO:0043382(positive regulation of memory T cell differentiation);GO:0045591(positive regulation of regulatory T cell differentiation);GO:0002079(inner acrosomal membrane);GO:0001848(complement binding);GO:0004175(endopeptidase activity);GO:0004857(enzyme inhibitor activity);GO:0006508(proteolysis);GO:0045916(negative regulation of complement activation);GO:0001669(acrosomal vesicle);GO:0005737(cytoplasm);GO:0005794(Golgi apparatus);GO:0016323(basolateral plasma membrane);GO:0016323(basolateral plasma membrane)","04610(Complement and coagulation cascades);05162(Measles);05162(Measles)","K04007","NA","CD46 molecule [Source:HGNC Symbol;Acc:HGNC:6953]",{"v":6.32996787999541,"d":"6.33"},{"v":18.9847637867478,"d":"18.98"},{"v":0.333423578565355,"d":"0.33"},{"v":-1.58457196453871,"d":"-1.58"},{"v":0.0199201355996134,"d":"0.02"},{"v":0.44014361998265,"d":"0.44"},"down","yes"]
["MSTRG.5134","MINDY2","ENST00000559228;ENST00000316848;ENST00000559745;ENST00000450403","GO:0004843(thiol-dependent ubiquitin-specific protease activity);GO:0006508(proteolysis);GO:1990380(Lys48-specific deubiquitinase activity);GO:0071108(protein K48-linked deubiquitination);GO:0005654(nucleoplasm);GO:0016787(hydrolase activity);GO:0008233(peptidase activity);GO:0008234(cysteine-type peptidase activity);GO:0036459(thiol-dependent ubiquitinyl hydrolase activity);GO:0003674(molecular_function);GO:0008150(biological_process);GO:0005575(cellular_component);GO:0071796(K6-linked polyubiquitin binding);GO:0036435(K48-linked polyubiquitin binding);GO:0070530(K63-linked polyubiquitin binding);GO:0016807(cysteine-type carboxypeptidase activity);GO:0071795(K11-linked polyubiquitin binding);GO:0071795(K11-linked polyubiquitin binding)","NA","NA","NA","MINDY lysine 48 deubiquitinase 2 [Source:HGNC Symbol;Acc:HGNC:26954]",{"v":0.194334247937381,"d":"0.19"},{"v":0.598198131478739,"d":"0.60"},{"v":0.324866022996409,"d":"0.32"},{"v":-1.62208323154579,"d":"-1.62"},{"v":0.0199949347396799,"d":"0.02"},{"v":0.440987187060853,"d":"0.44"},"down","yes"]
["ENSG00000237649","KIFC1","ENST00000428849","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0051301(cell division);GO:0003777(microtubule motor activity);GO:0005856(cytoskeleton);GO:0007049(cell cycle);GO:0008017(microtubule binding);GO:0005874(microtubule);GO:0003774(motor activity);GO:0007018(microtubule-based movement);GO:0007283(spermatogenesis);GO:0005815(microtubule organizing center);GO:0005819(spindle);GO:0005768(endosome);GO:0005769(early endosome);GO:0016887(ATPase activity);GO:0090307(mitotic spindle assembly);GO:0005871(kinesin complex);GO:0007080(mitotic metaphase plate congression);GO:0000070(mitotic sister chromatid segregation)","NA","NA","NA","kinesin family member C1 [Source:HGNC Symbol;Acc:HGNC:6389]",{"v":0.756252979372197,"d":"0.76"},{"v":0.248872721076233,"d":"0.25"},{"v":3.03871382971116,"d":"3.04"},{"v":1.60346081573014,"d":"1.60"},{"v":0.0201164148165941,"d":"0.02"},{"v":0.44285533312875,"d":"0.44"},"up","yes"]
["ENSG00000211795","TRAV8-6","ENST00000390443","NA","NA","NA","NA","T-cell receptor alpha variable 8-6 [Source:HGNC Symbol;Acc:HGNC:12151]",{"v":5.01465,"d":"5.01"},{"v":1.661218,"d":"1.66"},{"v":3.01865859869084,"d":"3.02"},{"v":1.59390760155942,"d":"1.59"},{"v":0.0203477203171138,"d":"0.02"},{"v":0.446198410597787,"d":"0.45"},"up","yes"]
["MSTRG.7799","ICAM3","ENST00000160262;ENST00000589261;ENST00000589900;ENST00000585439;ENST00000587992;ENST00000589249;ENST00000589580;ENST00000590569;ENST00000592439;ENST00000592945","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0007155(cell adhesion);GO:0016337(single organismal cell-cell adhesion);GO:0050776(regulation of immune response);GO:0005886(plasma membrane);GO:0070062(extracellular exosome);GO:0002223(stimulatory C-type lectin receptor signaling pathway);GO:0005515(protein binding);GO:0005887(integral component of plasma membrane);GO:0005102(receptor binding);GO:0006909(phagocytosis);GO:0030198(extracellular matrix organization);GO:0005178(integrin binding);GO:0005178(integrin binding)","04514(Cell adhesion molecules (CAMs));04514(Cell adhesion molecules (CAMs))","K06486","NA","intercellular adhesion molecule 3 [Source:HGNC Symbol;Acc:HGNC:5346]",{"v":50.8306512467797,"d":"50.83"},{"v":151.669499302034,"d":"151.67"},{"v":0.335140891746176,"d":"0.34"},{"v":-1.57716036919183,"d":"-1.58"},{"v":0.0203632978747631,"d":"0.02"},{"v":0.446198410597787,"d":"0.45"},"down","yes"]
["ENSG00000165115","KIF27","ENST00000297814;ENST00000413982;ENST00000376347;ENST00000495062","GO:0005737(cytoplasm);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0003777(microtubule motor activity);GO:0005856(cytoskeleton);GO:0042995(cell projection);GO:0008017(microtubule binding);GO:0005874(microtubule);GO:0007018(microtubule-based movement);GO:0060271(cilium assembly);GO:0005929(cilium);GO:0070062(extracellular exosome);GO:0030030(cell projection organization);GO:0005871(kinesin complex);GO:0008574(ATP-dependent microtubule motor activity, plus-end-directed);GO:0003774(motor activity);GO:0003774(motor activity)","NA","NA","NA","kinesin family member 27 [Source:HGNC Symbol;Acc:HGNC:18632]",{"v":0.393843359727626,"d":"0.39"},{"v":1.2036568688716,"d":"1.20"},{"v":0.327205676229676,"d":"0.33"},{"v":-1.61173031910962,"d":"-1.61"},{"v":0.0204300420209917,"d":"0.02"},{"v":0.446198410597787,"d":"0.45"},"down","yes"]
["ENSG00000204149","AGAP6","ENST00000412531;ENST00000374056;ENST00000618025","GO:0046872(metal ion binding);GO:0043547(positive regulation of GTPase activity);GO:0005096(GTPase activator activity);GO:0005096(GTPase activator activity)","NA","NA","NA","ArfGAP with GTPase domain, ankyrin repeat and PH domain 6 [Source:HGNC Symbol;Acc:HGNC:23466]",{"v":2.5280026693038,"d":"2.53"},{"v":0.86458837721519,"d":"0.86"},{"v":2.9239378366922,"d":"2.92"},{"v":1.54791263972769,"d":"1.55"},{"v":0.0204374601948721,"d":"0.02"},{"v":0.446198410597787,"d":"0.45"},"up","yes"]
["MSTRG.5169","APH1B","ENST00000261879;ENST00000380343;ENST00000559971;ENST00000560890;ENST00000380340;ENST00000558631;ENST00000560716","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016485(protein processing);GO:0043085(positive regulation of catalytic activity);GO:0007219(Notch signaling pathway);GO:0005886(plasma membrane);GO:0005783(endoplasmic reticulum);GO:0004175(endopeptidase activity);GO:0005887(integral component of plasma membrane);GO:0005515(protein binding);GO:0008233(peptidase activity);GO:0007220(Notch receptor processing);GO:0070765(gamma-secretase complex);GO:0048013(ephrin receptor signaling pathway);GO:0043065(positive regulation of apoptotic process);GO:0031293(membrane protein intracellular domain proteolysis);GO:0030133(transport vesicle);GO:0030133(transport vesicle)","04330(Notch signaling pathway);05010(Alzheimer's disease);05010(Alzheimer's disease)","K06172","NA","aph-1 homolog B, gamma-secretase subunit [Source:HGNC Symbol;Acc:HGNC:24080]",{"v":1.27477383327266,"d":"1.27"},{"v":3.83933841827448,"d":"3.84"},{"v":0.33202955676035,"d":"0.33"},{"v":-1.59061642110555,"d":"-1.59"},{"v":0.0204535394992508,"d":"0.02"},{"v":0.446198410597787,"d":"0.45"},"down","yes"]
["MSTRG.1419","LBR","ENST00000272163;ENST00000487054;ENST00000488632;ENST00000424022;ENST00000421383;ENST00000441022","GO:0003723(RNA binding);GO:0005634(nucleus);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0055114(oxidation-reduction process);GO:0031965(nuclear membrane);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0016628(oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor);GO:0005637(nuclear inner membrane);GO:0005635(nuclear envelope);GO:0016627(oxidoreductase activity, acting on the CH-CH group of donors);GO:0050613(delta14-sterol reductase activity);GO:0006695(cholesterol biosynthetic process);GO:0016126(sterol biosynthetic process);GO:0070087(chromo shadow domain binding);GO:0005521(lamin binding);GO:0005639(integral component of nuclear inner membrane);GO:0005639(integral component of nuclear inner membrane)","NA","NA","NA","lamin B receptor [Source:HGNC Symbol;Acc:HGNC:6518]",{"v":7.68163875233023,"d":"7.68"},{"v":22.8770261584554,"d":"22.88"},{"v":0.335779602607618,"d":"0.34"},{"v":-1.57441350043915,"d":"-1.57"},{"v":0.0206971373846803,"d":"0.02"},{"v":0.450623028627758,"d":"0.45"},"down","yes"]
["MSTRG.13847","ALKBH4","ENST00000292566;ENST00000490528;ENST00000498283","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003779(actin binding);GO:0005515(protein binding);GO:0051213(dioxygenase activity);GO:0030496(midbody);GO:0016706(oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors);GO:0070938(contractile ring);GO:0006482(protein demethylation);GO:0032451(demethylase activity);GO:0031032(actomyosin structure organization);GO:0036090(cleavage furrow ingression);GO:0070988(demethylation);GO:0070988(demethylation)","NA","NA","NA","alkB homolog 4, lysine demethylase [Source:HGNC Symbol;Acc:HGNC:21900]",{"v":1.60750069766436,"d":"1.61"},{"v":0.545093605536332,"d":"0.55"},{"v":2.94903605791284,"d":"2.95"},{"v":1.56024346236371,"d":"1.56"},{"v":0.0207442096050563,"d":"0.02"},{"v":0.450623028627758,"d":"0.45"},"up","yes"]
["ENSG00000178146","AL672207.1","ENST00000328462","NA","NA","NA","NA",null,{"v":1.057088,"d":"1.06"},{"v":3.240763,"d":"3.24"},{"v":0.326184913861335,"d":"0.33"},{"v":-1.61623803632237,"d":"-1.62"},{"v":0.0207686248869296,"d":"0.02"},{"v":0.450623028627758,"d":"0.45"},"down","yes"]
["MSTRG.3332","SLC48A1","ENST00000442218;ENST00000547002;ENST00000476104","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0006810(transport);GO:0005765(lysosomal membrane);GO:0005515(protein binding);GO:0005764(lysosome);GO:0005768(endosome);GO:0010008(endosome membrane);GO:0015232(heme transporter activity);GO:0015886(heme transport);GO:0005886(plasma membrane);GO:0020037(heme binding);GO:0020037(heme binding)","NA","NA","NA","solute carrier family 48 member 1 [Source:HGNC Symbol;Acc:HGNC:26035]",{"v":2.1952059904491,"d":"2.20"},{"v":0.759115149359886,"d":"0.76"},{"v":2.89179578658149,"d":"2.89"},{"v":1.5319656753566,"d":"1.53"},{"v":0.02093206605477,"d":"0.02"},{"v":0.453352409049532,"d":"0.45"},"up","yes"]
["MSTRG.4630","MOAP1","ENST00000298894;ENST00000556883","GO:0005515(protein binding);GO:0006915(apoptotic process);GO:0005737(cytoplasm);GO:0043065(positive regulation of apoptotic process);GO:0005829(cytosol);GO:0090200(positive regulation of release of cytochrome c from mitochondria);GO:0031625(ubiquitin protein ligase binding);GO:0005739(mitochondrion);GO:0008625(extrinsic apoptotic signaling pathway via death domain receptors);GO:0097192(extrinsic apoptotic signaling pathway in absence of ligand);GO:0097190(apoptotic signaling pathway);GO:0008630(intrinsic apoptotic signaling pathway in response to DNA damage);GO:0005741(mitochondrial outer membrane);GO:0001844(protein insertion into mitochondrial membrane involved in apoptotic signaling pathway);GO:0001844(protein insertion into mitochondrial membrane involved in apoptotic signaling pathway)","NA","NA","NA","modulator of apoptosis 1 [Source:HGNC Symbol;Acc:HGNC:16658]",{"v":4.84432577571935,"d":"4.84"},{"v":1.6727827599527,"d":"1.67"},{"v":2.89596825821921,"d":"2.90"},{"v":1.53404578958939,"d":"1.53"},{"v":0.0209734391826781,"d":"0.02"},{"v":0.453432952671112,"d":"0.45"},"up","yes"]
["ENSG00000181191","PJA1","ENST00000374584;ENST00000477231;ENST00000361478;ENST00000374571;ENST00000374583","GO:0016567(protein ubiquitination);GO:0061630(ubiquitin protein ligase activity);GO:0046872(metal ion binding);GO:0016740(transferase activity);GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0030163(protein catabolic process);GO:0030163(protein catabolic process)","NA","NA","NA","praja ring finger ubiquitin ligase 1 [Source:HGNC Symbol;Acc:HGNC:16648]",{"v":0.267976959255695,"d":"0.27"},{"v":0.849635073468078,"d":"0.85"},{"v":0.315402421138119,"d":"0.32"},{"v":-1.66473436009011,"d":"-1.66"},{"v":0.021032091392714,"d":"0.02"},{"v":0.453886101345989,"d":"0.45"},"down","yes"]
["MSTRG.15187","TXLNG","ENST00000380122;ENST00000485153","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0005829(cytosol);GO:0007049(cell cycle);GO:0030500(regulation of bone mineralization);GO:0019905(syntaxin binding);GO:0031965(nuclear membrane);GO:0046982(protein heterodimerization activity);GO:0051726(regulation of cell cycle);GO:0010564(regulation of cell cycle process);GO:0010564(regulation of cell cycle process)","NA","NA","NA","taxilin gamma [Source:HGNC Symbol;Acc:HGNC:18578]",{"v":2.99110137780269,"d":"2.99"},{"v":1.03774395874439,"d":"1.04"},{"v":2.88231153031404,"d":"2.88"},{"v":1.52722627546741,"d":"1.53"},{"v":0.0211060479118341,"d":"0.02"},{"v":0.454667314766201,"d":"0.45"},"up","yes"]
["MSTRG.5015","LRRC57","ENST00000397130;ENST00000323443;ENST00000569830","GO:0016020(membrane);GO:0070062(extracellular exosome);GO:0070062(extracellular exosome)","NA","NA","NA","leucine rich repeat containing 57 [Source:HGNC Symbol;Acc:HGNC:26719]",{"v":0.306066554104018,"d":"0.31"},{"v":0.93139059267932,"d":"0.93"},{"v":0.328612460239222,"d":"0.33"},{"v":-1.60554090983821,"d":"-1.61"},{"v":0.0211856220334896,"d":"0.02"},{"v":0.455286903946588,"d":"0.46"},"down","yes"]
["MSTRG.1762","DDIT4","ENST00000307365;ENST00000473155;ENST00000471240","GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0071889(14-3-3 protein binding);GO:0001666(response to hypoxia);GO:0009968(negative regulation of signal transduction);GO:0032007(negative regulation of TOR signaling);GO:0042771(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator);GO:0043241(protein complex disassembly);GO:0045820(negative regulation of glycolytic process);GO:0071549(cellular response to dexamethasone stimulus);GO:0072593(reactive oxygen species metabolic process);GO:0005739(mitochondrion);GO:0006915(apoptotic process);GO:0051607(defense response to virus);GO:0008283(cell proliferation);GO:0007420(brain development);GO:0030182(neuron differentiation);GO:0005622(intracellular);GO:0001764(neuron migration);GO:0048011(neurotrophin TRK receptor signaling pathway);GO:1902532(negative regulation of intracellular signal transduction);GO:0033137(negative regulation of peptidyl-serine phosphorylation);GO:0010801(negative regulation of peptidyl-threonine phosphorylation);GO:1901216(positive regulation of neuron death);GO:1901216(positive regulation of neuron death)","04151(PI3K-Akt signaling pathway);04150(mTOR signaling pathway);04140(Autophagy - animal);05206(MicroRNAs in cancer);05206(MicroRNAs in cancer)","K08270","NA","DNA damage inducible transcript 4 [Source:HGNC Symbol;Acc:HGNC:24944]",{"v":13.5462326239067,"d":"13.55"},{"v":4.71823976190476,"d":"4.72"},{"v":2.87103523930248,"d":"2.87"},{"v":1.52157103840122,"d":"1.52"},{"v":0.0212104262675665,"d":"0.02"},{"v":0.455286903946588,"d":"0.46"},"up","yes"]
["MSTRG.8407","MBOAT7","ENST00000494142;ENST00000437868;ENST00000245615;ENST00000453320;ENST00000391754;ENST00000491216;ENST00000495968;ENST00000474910;ENST00000464098;ENST00000338624;ENST00000449249;MSTRG.8407.1;ENST00000414665;ENST00000431666;ENST00000495279","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016740(transferase activity);GO:0016746(transferase activity, transferring acyl groups);GO:0006629(lipid metabolic process);GO:0005515(protein binding);GO:0008654(phospholipid biosynthetic process);GO:0005789(endoplasmic reticulum membrane);GO:0003841(1-acylglycerol-3-phosphate O-acyltransferase activity);GO:0006644(phospholipid metabolic process);GO:0036149(phosphatidylinositol acyl-chain remodeling);GO:0021819(layer formation in cerebral cortex);GO:0047144(2-acylglycerol-3-phosphate O-acyltransferase activity);GO:0071617(lysophospholipid acyltransferase activity);GO:0021591(ventricular system development);GO:0046488(phosphatidylinositol metabolic process);GO:0046488(phosphatidylinositol metabolic process)","00564(Glycerophospholipid metabolism);00564(Glycerophospholipid metabolism)","K13516","EC:2.3.1.-","membrane bound O-acyltransferase domain containing 7 [Source:HGNC Symbol;Acc:HGNC:15505]",{"v":21.2760610150985,"d":"21.28"},{"v":62.9939996499724,"d":"62.99"},{"v":0.337747422505626,"d":"0.34"},{"v":-1.56598333511446,"d":"-1.57"},{"v":0.0212791328017362,"d":"0.02"},{"v":0.455384399237676,"d":"0.46"},"down","yes"]
["MSTRG.11359","NDUFB5","ENST00000259037;ENST00000496904;ENST00000493866;ENST00000471112;ENST00000359944;ENST00000482604;ENST00000472629;ENST00000468210;ENST00000493716;ENST00000611971;ENST00000491054;ENST00000477177;ENST00000488002;ENST00000480374;ENST00000476587","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005654(nucleoplasm);GO:0055114(oxidation-reduction process);GO:0005739(mitochondrion);GO:0005743(mitochondrial inner membrane);GO:0070469(respiratory chain);GO:0032981(mitochondrial respiratory chain complex I assembly);GO:0008137(NADH dehydrogenase (ubiquinone) activity);GO:0006120(mitochondrial electron transport, NADH to ubiquinone);GO:0005747(mitochondrial respiratory chain complex I);GO:0005747(mitochondrial respiratory chain complex I)","00190(Oxidative phosphorylation);04723(Retrograde endocannabinoid signaling);05010(Alzheimer's disease);05012(Parkinson's disease);05016(Huntington's disease);04932(Non-alcoholic fatty liver disease (NAFLD));04932(Non-alcoholic fatty liver disease (NAFLD))","K03961","NA","NADH:ubiquinone oxidoreductase subunit B5 [Source:HGNC Symbol;Acc:HGNC:7700]",{"v":0.636706050587634,"d":"0.64"},{"v":1.92262874501788,"d":"1.92"},{"v":0.331164325009461,"d":"0.33"},{"v":-1.59438082936915,"d":"-1.59"},{"v":0.0213198411243232,"d":"0.02"},{"v":0.455384399237676,"d":"0.46"},"down","yes"]
["ENSG00000073737","DHRS9","ENST00000357546;ENST00000450153;ENST00000436483;ENST00000428522;ENST00000602501;ENST00000412271;ENST00000421653","GO:0016020(membrane);GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0043231(intracellular membrane-bounded organelle);GO:0030176(integral component of endoplasmic reticulum membrane);GO:0031090(organelle membrane);GO:0030855(epithelial cell differentiation);GO:0004745(retinol dehydrogenase activity);GO:0047035(testosterone dehydrogenase (NAD+) activity);GO:0042572(retinol metabolic process);GO:0004022(alcohol dehydrogenase (NAD) activity);GO:0042448(progesterone metabolic process);GO:0008209(androgen metabolic process);GO:0016854(racemase and epimerase activity);GO:0042904(9-cis-retinoic acid biosynthetic process);GO:0002138(retinoic acid biosynthetic process);GO:0002138(retinoic acid biosynthetic process)","00830(Retinol metabolism);00830(Retinol metabolism)","K11149","EC:1.1.-.-","dehydrogenase/reductase 9 [Source:HGNC Symbol;Acc:HGNC:16888]",{"v":0.8044345792,"d":"0.80"},{"v":2.42186759626667,"d":"2.42"},{"v":0.332154648107123,"d":"0.33"},{"v":-1.59007299153749,"d":"-1.59"},{"v":0.0213284173036081,"d":"0.02"},{"v":0.455384399237676,"d":"0.46"},"down","yes"]
["MSTRG.5722","IGSF6","ENST00000268389;ENST00000565499;ENST00000569602","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005887(integral component of plasma membrane);GO:0006955(immune response);GO:0007166(cell surface receptor signaling pathway);GO:0004888(transmembrane signaling receptor activity);GO:0004888(transmembrane signaling receptor activity)","NA","NA","NA","immunoglobulin superfamily member 6 [Source:HGNC Symbol;Acc:HGNC:5953]",{"v":13.1583661871461,"d":"13.16"},{"v":38.8451813629672,"d":"38.85"},{"v":0.338738698738334,"d":"0.34"},{"v":-1.56175527992236,"d":"-1.56"},{"v":0.0216706551182173,"d":"0.02"},{"v":0.460638603750354,"d":"0.46"},"down","yes"]
["MSTRG.8751","PELI1","ENST00000358912;ENST00000466177;ENST00000468869;ENST00000494203","GO:0016740(transferase activity);GO:0016567(protein ubiquitination);GO:0006468(protein phosphorylation);GO:0005515(protein binding);GO:0008063(Toll signaling pathway);GO:0006955(immune response);GO:0061630(ubiquitin protein ligase activity);GO:0005829(cytosol);GO:0004674(protein serine/threonine kinase activity);GO:0043123(positive regulation of I-kappaB kinase/NF-kappaB signaling);GO:0004842(ubiquitin-protein transferase activity);GO:0000209(protein polyubiquitination);GO:0001819(positive regulation of cytokine production);GO:0030890(positive regulation of B cell proliferation);GO:0031398(positive regulation of protein ubiquitination);GO:0032088(negative regulation of NF-kappaB transcription factor activity);GO:0032496(response to lipopolysaccharide);GO:0034141(positive regulation of toll-like receptor 3 signaling pathway);GO:0034145(positive regulation of toll-like receptor 4 signaling pathway);GO:0042130(negative regulation of T cell proliferation);GO:0043331(response to dsRNA);GO:0050868(negative regulation of T cell activation);GO:0050871(positive regulation of B cell activation);GO:0070936(protein K48-linked ubiquitination);GO:0005634(nucleus);GO:0034450(ubiquitin-ubiquitin ligase activity);GO:0034450(ubiquitin-ubiquitin ligase activity)","NA","NA","NA","pellino E3 ubiquitin protein ligase 1 [Source:HGNC Symbol;Acc:HGNC:8827]",{"v":12.5462146446061,"d":"12.55"},{"v":37.0220153258182,"d":"37.02"},{"v":0.338885242583126,"d":"0.34"},{"v":-1.56113128165855,"d":"-1.56"},{"v":0.0217085828399191,"d":"0.02"},{"v":0.460638603750354,"d":"0.46"},"down","yes"]
["MSTRG.14927","TLR4","ENST00000355622;ENST00000394487;ENST00000472304;ENST00000490685","GO:0070373(negative regulation of ERK1 and ERK2 cascade);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0005737(cytoplasm);GO:0050729(positive regulation of inflammatory response);GO:0032755(positive regulation of interleukin-6 production);GO:0071222(cellular response to lipopolysaccharide);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0007165(signal transduction);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0004888(transmembrane signaling receptor activity);GO:0048471(perinuclear region of cytoplasm);GO:0002376(immune system process);GO:0002755(MyD88-dependent toll-like receptor signaling pathway);GO:0045087(innate immune response);GO:0050707(regulation of cytokine secretion);GO:0006954(inflammatory response);GO:0042742(defense response to bacterium);GO:0005887(integral component of plasma membrane);GO:0050829(defense response to Gram-negative bacterium);GO:0010628(positive regulation of gene expression);GO:0010008(endosome membrane);GO:0042116(macrophage activation);GO:0002224(toll-like receptor signaling pathway);GO:0006955(immune response);GO:0050718(positive regulation of interleukin-1 beta secretion);GO:0001530(lipopolysaccharide binding);GO:0001875(lipopolysaccharide receptor activity);GO:0004872(receptor activity);GO:0005102(receptor binding);GO:0046982(protein heterodimerization activity);GO:0000187(activation of MAPK activity);GO:0002756(MyD88-independent toll-like receptor signaling pathway);GO:0007249(I-kappaB kinase/NF-kappaB signaling);GO:0007252(I-kappaB phosphorylation);GO:0010572(positive regulation of platelet activation);GO:0016046(detection of fungus);GO:0031663(lipopolysaccharide-mediated signaling pathway);GO:0032496(response to lipopolysaccharide);GO:0032497(detection of lipopolysaccharide);GO:0032689(negative regulation of interferon-gamma production);GO:0032700(negative regulation of interleukin-17 production);GO:0032707(negative regulation of interleukin-23 production);GO:0032715(negative regulation of interleukin-6 production);GO:0032720(negative regulation of tumor necrosis factor production);GO:0032722(positive regulation of chemokine production);GO:0032727(positive regulation of interferon-alpha production);GO:0032728(positive regulation of interferon-beta production);GO:0032729(positive regulation of interferon-gamma production);GO:0032732(positive regulation of interleukin-1 production);GO:0032733(positive regulation of interleukin-10 production);GO:0032735(positive regulation of interleukin-12 production);GO:0032757(positive regulation of interleukin-8 production);GO:0032760(positive regulation of tumor necrosis factor production);GO:0034128(negative regulation of MyD88-independent toll-like receptor signaling pathway);GO:0034142(toll-like receptor 4 signaling pathway);GO:0035666(TRIF-dependent toll-like receptor signaling pathway);GO:0042088(T-helper 1 type immune response);GO:0042346(positive regulation of NF-kappaB import into nucleus);GO:0042535(positive regulation of tumor necrosis factor biosynthetic process);GO:0043032(positive regulation of macrophage activation);GO:0045084(positive regulation of interleukin-12 biosynthetic process);GO:0045416(positive regulation of interleukin-8 biosynthetic process);GO:0045429(positive regulation of nitric oxide biosynthetic process);GO:0045671(negative regulation of osteoclast differentiation);GO:0050702(interleukin-1 beta secretion);GO:0051092(positive regulation of NF-kappaB transcription factor activity);GO:0051770(positive regulation of nitric-oxide synthase biosynthetic process);GO:0060729(intestinal epithelial structure maintenance);GO:0070266(necroptotic process);GO:0071260(cellular response to mechanical stimulus);GO:0097190(apoptotic signaling pathway);GO:0140052(-);GO:1900017(positive regulation of cytokine production involved in inflammatory response);GO:1900227(positive regulation of NLRP3 inflammasome complex assembly);GO:1903223(positive regulation of oxidative stress-induced neuron death);GO:1903428(positive regulation of reactive oxygen species biosynthetic process);GO:1904646(cellular response to amyloid-beta);GO:0005622(intracellular);GO:0009897(external side of plasma membrane);GO:0009986(cell surface);GO:0031226(intrinsic component of plasma membrane);GO:0043235(receptor complex);GO:0046696(lipopolysaccharide receptor complex);GO:0002218(activation of innate immune response);GO:0002322(B cell proliferation involved in immune response);GO:0002537(nitric oxide production involved in inflammatory response);GO:0002730(regulation of dendritic cell cytokine production);GO:0009617(response to bacterium);GO:0014002(astrocyte development);GO:0030890(positive regulation of B cell proliferation);GO:0032609(interferon-gamma production);GO:0032874(positive regulation of stress-activated MAPK cascade);GO:0043123(positive regulation of I-kappaB kinase/NF-kappaB signaling);GO:0045348(positive regulation of MHC class II biosynthetic process);GO:0045359(positive regulation of interferon-beta biosynthetic process);GO:0046330(positive regulation of JNK cascade);GO:0050671(positive regulation of lymphocyte proliferation);GO:0050727(regulation of inflammatory response);GO:0060907(positive regulation of macrophage cytokine production);GO:0070374(positive regulation of ERK1 and ERK2 cascade);GO:0070430(positive regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway);GO:0070434(positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway);GO:0071223(cellular response to lipoteichoic acid);GO:0071223(cellular response to lipoteichoic acid)","04064(NF-kappa B signaling pathway);04066(HIF-1 signaling pathway);04151(PI3K-Akt signaling pathway);04145(Phagosome);04217(Necroptosis);04620(Toll-like receptor signaling pathway);04621(NOD-like receptor signaling pathway);05205(Proteoglycans in cancer);05323(Rheumatoid arthritis);05321(Inflammatiory bowel disease (IBD));05130(Pathogenic Escherichia coli infection);05132(Salmonella infection);05133(Pertussis);05134(Legionellosis);05152(Tuberculosis);05162(Measles);05164(Influenza A);05161(Hepatitis B);05146(Amoebiasis);05144(Malaria);05145(Toxoplasmosis);05140(Leishmaniasis);05142(Chagas disease (American trypanosomiasis));05142(Chagas disease (American trypanosomiasis))","K10160","NA","toll like receptor 4 [Source:HGNC Symbol;Acc:HGNC:11850]",{"v":6.81296710064688,"d":"6.81"},{"v":20.111865494863,"d":"20.11"},{"v":0.338753613004575,"d":"0.34"},{"v":-1.56169176115595,"d":"-1.56"},{"v":0.0217196853872653,"d":"0.02"},{"v":0.460638603750354,"d":"0.46"},"down","yes"]
["MSTRG.9137","HNMT","ENST00000280097;ENST00000467390;ENST00000475675;ENST00000329366;ENST00000480534;ENST00000485653;ENST00000280096","GO:0005737(cytoplasm);GO:0008168(methyltransferase activity);GO:0016740(transferase activity);GO:0032259(methylation);GO:0008170(N-methyltransferase activity);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0006548(histidine catabolic process);GO:0043005(neuron projection);GO:0007420(brain development);GO:1903955(positive regulation of protein targeting to mitochondrion);GO:0007585(respiratory gaseous exchange);GO:0046539(histamine N-methyltransferase activity);GO:0001695(histamine catabolic process);GO:0002347(response to tumor cell);GO:0006972(hyperosmotic response);GO:0014075(response to amine);GO:0035902(response to immobilization stress);GO:0042220(response to cocaine);GO:0051384(response to glucocorticoid);GO:0070555(response to interleukin-1);GO:0070555(response to interleukin-1)","00340(Histidine metabolism);00340(Histidine metabolism)","K00546","EC:2.1.1.8","histamine N-methyltransferase [Source:HGNC Symbol;Acc:HGNC:5028]",{"v":0.682464935660219,"d":"0.68"},{"v":2.04236114192599,"d":"2.04"},{"v":0.334154876750465,"d":"0.33"},{"v":-1.58141116544854,"d":"-1.58"},{"v":0.0217926229756351,"d":"0.02"},{"v":0.460638603750354,"d":"0.46"},"down","yes"]
["MSTRG.9074","RALB","ENST00000420510;ENST00000272519;ENST00000449649;MSTRG.9074.7;ENST00000470417;ENST00000412383;ENST00000447591;ENST00000431732","GO:0005622(intracellular);GO:0005525(GTP binding);GO:0016020(membrane);GO:0000166(nucleotide binding);GO:0007165(signal transduction);GO:0003924(GTPase activity);GO:0005886(plasma membrane);GO:0007265(Ras protein signal transduction);GO:0051301(cell division);GO:0007049(cell cycle);GO:0006915(apoptotic process);GO:0030496(midbody);GO:0005515(protein binding);GO:0000145(exocyst);GO:0070062(extracellular exosome);GO:0001934(positive regulation of protein phosphorylation);GO:0071902(positive regulation of protein serine/threonine kinase activity);GO:0009267(cellular response to starvation);GO:0031625(ubiquitin protein ligase binding);GO:0005776(autophagosome);GO:0019003(GDP binding);GO:0032092(positive regulation of protein binding);GO:0000910(cytokinesis);GO:0032091(negative regulation of protein binding);GO:0051117(ATPase binding);GO:0071360(cellular response to exogenous dsRNA);GO:0001928(regulation of exocyst assembly);GO:0060178(regulation of exocyst localization);GO:2000786(positive regulation of autophagosome assembly);GO:2000786(positive regulation of autophagosome assembly)","04014(Ras signaling pathway);04015(Rap1 signaling pathway);04072(Phospholipase D signaling pathway);05200(Pathways in cancer);05210(Colorectal cancer);05212(Pancreatic cancer);05212(Pancreatic cancer)","K07835","NA","RAS like proto-oncogene B [Source:HGNC Symbol;Acc:HGNC:9840]",{"v":6.75044200657895,"d":"6.75"},{"v":19.9625411026316,"d":"19.96"},{"v":0.338155446837831,"d":"0.34"},{"v":-1.5642415027334,"d":"-1.56"},{"v":0.0217989933388649,"d":"0.02"},{"v":0.460638603750354,"d":"0.46"},"down","yes"]
["MSTRG.8921","IGKV3D-15","ENST00000417279","GO:0016020(membrane);GO:0005886(plasma membrane);GO:0005576(extracellular region);GO:0002376(immune system process);GO:0002377(immunoglobulin production);GO:0006955(immune response);GO:0005615(extracellular space);GO:0003823(antigen binding);GO:0002250(adaptive immune response)","NA","NA","NA","immunoglobulin kappa variable 3D-15 (gene/pseudogene) [Source:HGNC Symbol;Acc:HGNC:5824]",{"v":12.66727,"d":"12.67"},{"v":4.339259,"d":"4.34"},{"v":2.91922422699359,"d":"2.92"},{"v":1.54558502918469,"d":"1.55"},{"v":0.0218185906313668,"d":"0.02"},{"v":0.460638603750354,"d":"0.46"},"up","yes"]
["ENSG00000171219","CDC42BPG","ENST00000342711;ENST00000480767","GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0005829(cytosol);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0035556(intracellular signal transduction);GO:0005515(protein binding);GO:0000287(magnesium ion binding);GO:0005815(microtubule organizing center);GO:0031532(actin cytoskeleton reorganization);GO:0031252(cell leading edge);GO:0031252(cell leading edge)","NA","NA","NA","CDC42 binding protein kinase gamma [Source:HGNC Symbol;Acc:HGNC:29829]",{"v":0.763968756217277,"d":"0.76"},{"v":0.260850454515707,"d":"0.26"},{"v":2.9287614531309,"d":"2.93"},{"v":1.55029069086147,"d":"1.55"},{"v":0.0218422722754901,"d":"0.02"},{"v":0.460638603750354,"d":"0.46"},"up","yes"]
["MSTRG.10224","TOP3B;PPM1F","MSTRG.10224.1;ENST00000436282;ENST00000623652;ENST00000397495;ENST00000496143;ENST00000434517;ENST00000470338;ENST00000444502;ENST00000357179;ENST00000437103;ENST00000487485;ENST00000407142;ENST00000445205;ENST00000497072;ENST00000484588;ENST00000398793;ENST00000424647;ENST00000449704;ENST00000442653;ENST00000489581;ENST00000457179","GO:0003723(RNA binding);GO:0016853(isomerase activity);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0003916(DNA topoisomerase activity);GO:0003917(DNA topoisomerase type I activity);GO:0006265(DNA topological change);GO:0005634(nucleus);GO:0007059(chromosome segregation);GO:0000793(condensed chromosome);GO:0046872(metal ion binding);GO:0016787(hydrolase activity);GO:0003824(catalytic activity);GO:0006470(protein dephosphorylation);GO:0005829(cytosol);GO:0004721(phosphoprotein phosphatase activity);GO:0006915(apoptotic process);GO:0004722(protein serine/threonine phosphatase activity);GO:0043169(cation binding);GO:0010628(positive regulation of gene expression);GO:0043234(protein complex);GO:0045892(negative regulation of transcription, DNA-templated);GO:0035690(cellular response to drug);GO:0043280(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process);GO:0097193(intrinsic apoptotic signaling pathway);GO:0006469(negative regulation of protein kinase activity);GO:0051496(positive regulation of stress fiber assembly);GO:0035970(peptidyl-threonine dephosphorylation);GO:0010634(positive regulation of epithelial cell migration);GO:0045927(positive regulation of growth);GO:0016791(phosphatase activity);GO:0010811(positive regulation of cell-substrate adhesion);GO:0050921(positive regulation of chemotaxis);GO:0051894(positive regulation of focal adhesion assembly);GO:0044387(negative regulation of protein kinase activity by regulation of protein phosphorylation);GO:0033137(negative regulation of peptidyl-serine phosphorylation);GO:0033192(calmodulin-dependent protein phosphatase activity);GO:0016576(histone dephosphorylation);GO:0048471(perinuclear region of cytoplasm);GO:0000793(condensed chromosome)","03440(Homologous recombination);03460(Fanconi anemia pathway);03460(Fanconi anemia pathway)","K03165","EC:5.99.1.2","topoisomerase (DNA) III beta [Source:HGNC Symbol;Acc:HGNC:11993];protein phosphatase, Mg2+/Mn2+ dependent 1F [Source:HGNC Symbol;Acc:HGNC:19388]",{"v":2.93178543795725,"d":"2.93"},{"v":8.64001107033902,"d":"8.64"},{"v":0.339326583506589,"d":"0.34"},{"v":-1.55925363686675,"d":"-1.56"},{"v":0.021920716943807,"d":"0.02"},{"v":0.461484743771546,"d":"0.46"},"down","yes"]
["ENSG00000177225","GATD1","ENST00000319863;ENST00000532839;ENST00000530209;ENST00000465313;ENST00000528602;ENST00000533960;ENST00000529966;ENST00000524550;ENST00000526325;ENST00000529362;ENST00000528309;ENST00000532320;ENST00000526650","GO:0005576(extracellular region);GO:0003674(molecular_function);GO:0008150(biological_process);GO:0070062(extracellular exosome);GO:0070062(extracellular exosome)","NA","NA","NA","glutamine amidotransferase like class 1 domain containing 1 [Source:HGNC Symbol;Acc:HGNC:26616]",{"v":1.54537303157895,"d":"1.55"},{"v":0.529739184029038,"d":"0.53"},{"v":2.91723375987652,"d":"2.92"},{"v":1.54460099497879,"d":"1.54"},{"v":0.0219793793283389,"d":"0.02"},{"v":0.461912191748441,"d":"0.46"},"up","yes"]
["MSTRG.9905","RGS19;MIR6813","MSTRG.9905.3;MSTRG.9905.2;ENST00000332298;MSTRG.9905.1;ENST00000395042;ENST00000621638;ENST00000493165","GO:0016020(membrane);GO:0043547(positive regulation of GTPase activity);GO:0005515(protein binding);GO:0006914(autophagy);GO:0005096(GTPase activator activity);GO:0031410(cytoplasmic vesicle);GO:0007186(G-protein coupled receptor signaling pathway);GO:0005794(Golgi apparatus);GO:0007264(small GTPase mediated signal transduction);GO:0009968(negative regulation of signal transduction);GO:0005834(heterotrimeric G-protein complex);GO:0001965(G-protein alpha-subunit binding);GO:0005737(cytoplasm);GO:0005903(brush border);GO:0030136(clathrin-coated vesicle);GO:0045121(membrane raft);GO:0045121(membrane raft)","NA","NA","NA","regulator of G protein signaling 19 [Source:HGNC Symbol;Acc:HGNC:13735];microRNA 6813 [Source:HGNC Symbol;Acc:HGNC:50017]",{"v":10.4952308064389,"d":"10.50"},{"v":30.9074274040047,"d":"30.91"},{"v":0.339569860320339,"d":"0.34"},{"v":-1.55821968162667,"d":"-1.56"},{"v":0.0221350721669553,"d":"0.02"},{"v":0.464373761384104,"d":"0.46"},"down","yes"]
["ENSG00000213085","CFAP45","ENST00000475911;ENST00000479861;ENST00000476696;ENST00000368099;ENST00000426543","GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0042995(cell projection);GO:0005929(cilium);GO:0005929(cilium)","NA","NA","NA","cilia and flagella associated protein 45 [Source:HGNC Symbol;Acc:HGNC:17229]",{"v":0.423489671619048,"d":"0.42"},{"v":1.30914620647619,"d":"1.31"},{"v":0.323485390343794,"d":"0.32"},{"v":-1.62822753801582,"d":"-1.63"},{"v":0.0222605430224266,"d":"0.02"},{"v":0.465303886259356,"d":"0.47"},"down","yes"]
["MSTRG.4999","NUSAP1","ENST00000450592;ENST00000560177;ENST00000260359;ENST00000558582;ENST00000560898;ENST00000560747;ENST00000559596;ENST00000559659;ENST00000560318;ENST00000558123;ENST00000414849","GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0003677(DNA binding);GO:0051301(cell division);GO:0005694(chromosome);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0007049(cell cycle);GO:0005874(microtubule);GO:0000226(microtubule cytoskeleton organization);GO:0005730(nucleolus);GO:0005819(spindle);GO:0000281(mitotic cytokinesis);GO:0040001(establishment of mitotic spindle localization);GO:0000070(mitotic sister chromatid segregation);GO:0007076(mitotic chromosome condensation);GO:0045840(positive regulation of mitotic nuclear division);GO:0008017(microtubule binding);GO:0005876(spindle microtubule);GO:0005876(spindle microtubule)","NA","NA","NA","nucleolar and spindle associated protein 1 [Source:HGNC Symbol;Acc:HGNC:18538]",{"v":1.15455655095652,"d":"1.15"},{"v":0.398017342956522,"d":"0.40"},{"v":2.90076945486931,"d":"2.90"},{"v":1.53643563868182,"d":"1.54"},{"v":0.0222605430224266,"d":"0.02"},{"v":0.465303886259356,"d":"0.47"},"up","yes"]
["MSTRG.259","LDLRAP1","ENST00000374338;ENST00000474283;ENST00000488127;ENST00000485476;ENST00000484476;ENST00000470950;ENST00000462394","GO:0042632(cholesterol homeostasis);GO:0006810(transport);GO:0005737(cytoplasm);GO:0009967(positive regulation of signal transduction);GO:0006629(lipid metabolic process);GO:0005829(cytosol);GO:0008202(steroid metabolic process);GO:0005515(protein binding);GO:0008203(cholesterol metabolic process);GO:0005886(plasma membrane);GO:0006897(endocytosis);GO:0061024(membrane organization);GO:0005769(early endosome);GO:0009925(basal plasma membrane);GO:0048260(positive regulation of receptor-mediated endocytosis);GO:0009898(cytoplasmic side of plasma membrane);GO:0030424(axon);GO:0030665(clathrin-coated vesicle membrane);GO:0030159(receptor signaling complex scaffold activity);GO:0030276(clathrin binding);GO:0030121(AP-1 adaptor complex);GO:0035615(clathrin adaptor activity);GO:0030122(AP-2 adaptor complex);GO:0001540(amyloid-beta binding);GO:0034383(low-density lipoprotein particle clearance);GO:0090118(receptor-mediated endocytosis involved in cholesterol transport);GO:0055037(recycling endosome);GO:0050750(low-density lipoprotein particle receptor binding);GO:0006898(receptor-mediated endocytosis);GO:1905602(positive regulation of receptor-mediated endocytosis involved in cholesterol transport);GO:0001784(phosphotyrosine residue binding);GO:0090003(regulation of establishment of protein localization to plasma membrane);GO:0005883(neurofilament);GO:0005546(phosphatidylinositol-4,5-bisphosphate binding);GO:0031623(receptor internalization);GO:0043393(regulation of protein binding);GO:0035591(signaling adaptor activity);GO:0035612(AP-2 adaptor complex binding);GO:0042982(amyloid precursor protein metabolic process);GO:0090205(positive regulation of cholesterol metabolic process);GO:0090205(positive regulation of cholesterol metabolic process)","04144(Endocytosis);04979(Cholesterol metabolism);04979(Cholesterol metabolism)","K12474","NA","low density lipoprotein receptor adaptor protein 1 [Source:HGNC Symbol;Acc:HGNC:18640]",{"v":17.9095099720215,"d":"17.91"},{"v":6.32305905725403,"d":"6.32"},{"v":2.83241225644968,"d":"2.83"},{"v":1.5020312643792,"d":"1.50"},{"v":0.022322715214015,"d":"0.02"},{"v":0.465303886259356,"d":"0.47"},"up","yes"]
["MSTRG.11254","PLSCR1","ENST00000342435;ENST00000487389;ENST00000472349;ENST00000494568;ENST00000448787;ENST00000490745;ENST00000469266;ENST00000488253;ENST00000463777;ENST00000477974;ENST00000478267;ENST00000483300;ENST00000489775;ENST00000486631;ENST00000468985;ENST00000493432;ENST00000470496;ENST00000462666;ENST00000484560","GO:0005634(nucleus);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005794(Golgi apparatus);GO:0006366(transcription from RNA polymerase II promoter);GO:0003677(DNA binding);GO:0005886(plasma membrane);GO:0005829(cytosol);GO:0005515(protein binding);GO:0006915(apoptotic process);GO:0045121(membrane raft);GO:0005730(nucleolus);GO:0005509(calcium ion binding);GO:0051607(defense response to virus);GO:0005887(integral component of plasma membrane);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0070062(extracellular exosome);GO:0010628(positive regulation of gene expression);GO:0031012(extracellular matrix);GO:0045071(negative regulation of viral genome replication);GO:0017124(SH3 domain binding);GO:0006953(acute-phase response);GO:0019899(enzyme binding);GO:0045089(positive regulation of innate immune response);GO:0005154(epidermal growth factor receptor binding);GO:0001077(transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0017128(phospholipid scramblase activity);GO:0042609(CD4 receptor binding);GO:0006659(phosphatidylserine biosynthetic process);GO:0017121(phospholipid scrambling);GO:0030168(platelet activation);GO:0033003(regulation of mast cell activation);GO:0035456(response to interferon-beta);GO:0060368(regulation of Fc receptor mediated stimulatory signaling pathway);GO:2000373(positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity);GO:2000373(positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity)","NA","NA","NA","phospholipid scramblase 1 [Source:HGNC Symbol;Acc:HGNC:9092]",{"v":1.63774281520737,"d":"1.64"},{"v":4.86565715184332,"d":"4.87"},{"v":0.336592317152252,"d":"0.34"},{"v":-1.57092584790709,"d":"-1.57"},{"v":0.0223339682991121,"d":"0.02"},{"v":0.465303886259356,"d":"0.47"},"down","yes"]
["ENSG00000196526","AFAP1","ENST00000420658;ENST00000505447;ENST00000358461;ENST00000614385;ENST00000513842","GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0003779(actin binding);GO:0005925(focal adhesion);GO:0015629(actin cytoskeleton);GO:0005856(cytoskeleton);GO:0009966(regulation of signal transduction);GO:0051493(regulation of cytoskeleton organization);GO:0051493(regulation of cytoskeleton organization)","NA","NA","NA","actin filament associated protein 1 [Source:HGNC Symbol;Acc:HGNC:24017]",{"v":0.49631652620566,"d":"0.50"},{"v":0.168975214826624,"d":"0.17"},{"v":2.93721494430353,"d":"2.94"},{"v":1.55444884541558,"d":"1.55"},{"v":0.0223884254652926,"d":"0.02"},{"v":0.465632848796293,"d":"0.47"},"up","yes"]
["ENSG00000129993","CBFA2T3","ENST00000268679;ENST00000563856;ENST00000327483;ENST00000563640;ENST00000566868;ENST00000569464;ENST00000563920","GO:0005634(nucleus);GO:0016020(membrane);GO:0046872(metal ion binding);GO:0005654(nucleoplasm);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0005794(Golgi apparatus);GO:0003714(transcription corepressor activity);GO:0005515(protein binding);GO:0045892(negative regulation of transcription, DNA-templated);GO:0000139(Golgi membrane);GO:0030154(cell differentiation);GO:0005730(nucleolus);GO:0008285(negative regulation of cell proliferation);GO:0001666(response to hypoxia);GO:0008283(cell proliferation);GO:0030851(granulocyte differentiation);GO:0032436(positive regulation of proteasomal ubiquitin-dependent protein catabolic process);GO:0045820(negative regulation of glycolytic process);GO:1903715(regulation of aerobic respiration);GO:1903715(regulation of aerobic respiration)","NA","NA","NA","CBFA2/RUNX1 translocation partner 3 [Source:HGNC Symbol;Acc:HGNC:1537]",{"v":1.28632469072338,"d":"1.29"},{"v":3.79912121567314,"d":"3.80"},{"v":0.33858479835197,"d":"0.34"},{"v":-1.56241089375821,"d":"-1.56"},{"v":0.0224357387180329,"d":"0.02"},{"v":0.465812354556124,"d":"0.47"},"down","yes"]
["MSTRG.3489","GLI1","ENST00000228682;ENST00000527742;ENST00000530789","GO:0003676(nucleic acid binding);GO:0045893(positive regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0008284(positive regulation of cell proliferation);GO:0007224(smoothened signaling pathway);GO:0005737(cytoplasm);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0005515(protein binding);GO:0007275(multicellular organism development);GO:0030154(cell differentiation);GO:0097542(ciliary tip);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0090090(negative regulation of canonical Wnt signaling pathway);GO:0044212(transcription regulatory region DNA binding);GO:0045740(positive regulation of DNA replication);GO:0001649(osteoblast differentiation);GO:0000977(RNA polymerase II regulatory region sequence-specific DNA binding);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:0003682(chromatin binding);GO:0003705(transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding);GO:0008017(microtubule binding);GO:0007283(spermatogenesis);GO:0007418(ventral midline development);GO:0008589(regulation of smoothened signaling pathway);GO:0009611(response to wounding);GO:0009913(epidermal cell differentiation);GO:0009953(dorsal/ventral pattern formation);GO:0009954(proximal/distal pattern formation);GO:0021696(cerebellar cortex morphogenesis);GO:0021938(smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation);GO:0021983(pituitary gland development);GO:0030324(lung development);GO:0030850(prostate gland development);GO:0045667(regulation of osteoblast differentiation);GO:0045880(positive regulation of smoothened signaling pathway);GO:0048546(digestive tract morphogenesis);GO:0060032(notochord regression);GO:0060070(canonical Wnt signaling pathway);GO:0097421(liver regeneration);GO:2000345(regulation of hepatocyte proliferation);GO:0005929(cilium);GO:0005930(axoneme);GO:0097546(ciliary base);GO:0097546(ciliary base)","04340(Hedgehog signaling pathway);04024(cAMP signaling pathway);05200(Pathways in cancer);05217(Basal cell carcinoma);05217(Basal cell carcinoma)","K16797","NA","GLI family zinc finger 1 [Source:HGNC Symbol;Acc:HGNC:4317]",{"v":0.199245227640343,"d":"0.20"},{"v":0.629401387488107,"d":"0.63"},{"v":0.316563057535535,"d":"0.32"},{"v":-1.65943519007552,"d":"-1.66"},{"v":0.0225788676048579,"d":"0.02"},{"v":0.467977149221513,"d":"0.47"},"down","yes"]
["MSTRG.13450","MRM2","ENST00000486040;ENST00000467199;ENST00000242257;ENST00000407040;ENST00000440306","GO:0008168(methyltransferase activity);GO:0016740(transferase activity);GO:0001510(RNA methylation);GO:0032259(methylation);GO:0005739(mitochondrion);GO:0005730(nucleolus);GO:0006364(rRNA processing);GO:0005759(mitochondrial matrix);GO:0008283(cell proliferation);GO:0000451(rRNA 2'-O-methylation);GO:0008650(rRNA (uridine-2'-O-)-methyltransferase activity);GO:0031167(rRNA methylation);GO:0031167(rRNA methylation)","NA","NA","NA","mitochondrial rRNA methyltransferase 2 [Source:HGNC Symbol;Acc:HGNC:16352]",{"v":4.74937920295463,"d":"4.75"},{"v":1.66413881498417,"d":"1.66"},{"v":2.85395614848381,"d":"2.85"},{"v":1.51296316773204,"d":"1.51"},{"v":0.0226856922029521,"d":"0.02"},{"v":0.469383342797164,"d":"0.47"},"up","yes"]
["ENSG00000176049","JAKMIP2","ENST00000616793;ENST00000265272","GO:0005794(Golgi apparatus);GO:0005515(protein binding);GO:0008017(microtubule binding);GO:0019900(kinase binding);GO:0019900(kinase binding)","NA","NA","NA","janus kinase and microtubule interacting protein 2 [Source:HGNC Symbol;Acc:HGNC:29067]",{"v":0.474154585013477,"d":"0.47"},{"v":0.162450732506739,"d":"0.16"},{"v":2.91875929210604,"d":"2.92"},{"v":1.54535523776584,"d":"1.55"},{"v":0.0227394138283138,"d":"0.02"},{"v":0.469687858182769,"d":"0.47"},"up","yes"]
["MSTRG.9508","LRRFIP1;RBM44","ENST00000289175;ENST00000308482;ENST00000474195;ENST00000478958;ENST00000465870;ENST00000392000;ENST00000420665;ENST00000483443;ENST00000468950;ENST00000244815;ENST00000473815;ENST00000464608;ENST00000491996;ENST00000480583;ENST00000498053;ENST00000409864","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0005886(plasma membrane);GO:0042803(protein homodimerization activity);GO:0005515(protein binding);GO:0008150(biological_process);GO:0005575(cellular_component);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:0001078(transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0045296(cadherin binding);GO:0045892(negative regulation of transcription, DNA-templated);GO:0005856(cytoskeleton);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0032481(positive regulation of type I interferon production);GO:0003725(double-stranded RNA binding);GO:0051092(positive regulation of NF-kappaB transcription factor activity);GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0045171(intercellular bridge);GO:0045171(intercellular bridge)","NA","NA","NA","LRR binding FLII interacting protein 1 [Source:HGNC Symbol;Acc:HGNC:6702];RNA binding motif protein 44 [Source:HGNC Symbol;Acc:HGNC:24756]",{"v":9.09449891847248,"d":"9.09"},{"v":3.22614964062937,"d":"3.23"},{"v":2.81899475583479,"d":"2.82"},{"v":1.49518079407074,"d":"1.50"},{"v":0.0228145981013149,"d":"0.02"},{"v":0.470433887561702,"d":"0.47"},"up","yes"]
["ENSG00000183077","AFMID","ENST00000409257;ENST00000327898;ENST00000592988;ENST00000586542;ENST00000588199;ENST00000591256;ENST00000591538;ENST00000591952;ENST00000589256;ENST00000589664;ENST00000587750","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016787(hydrolase activity);GO:0008152(metabolic process);GO:0005829(cytosol);GO:0019441(tryptophan catabolic process to kynurenine);GO:0006569(tryptophan catabolic process);GO:0004061(arylformamidase activity);GO:0004061(arylformamidase activity)","00630(Glyoxylate and dicarboxylate metabolism);00380(Tryptophan metabolism);00380(Tryptophan metabolism)","K01432","EC:3.5.1.9","arylformamidase [Source:HGNC Symbol;Acc:HGNC:20910]",{"v":0.667789554347826,"d":"0.67"},{"v":0.21778044194664,"d":"0.22"},{"v":3.06634309481035,"d":"3.07"},{"v":1.61651912996752,"d":"1.62"},{"v":0.0229142023588179,"d":"0.02"},{"v":0.471680042401513,"d":"0.47"},"up","yes"]
["MSTRG.963","S100A9","ENST00000368738","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0005509(calcium ion binding);GO:0005886(plasma membrane);GO:0030054(cell junction);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0008017(microtubule binding);GO:0006915(apoptotic process);GO:0005615(extracellular space);GO:0006914(autophagy);GO:0098869(cellular oxidant detoxification);GO:0002376(immune system process);GO:0045087(innate immune response);GO:0006935(chemotaxis);GO:0006954(inflammatory response);GO:0042742(defense response to bacterium);GO:0050727(regulation of inflammatory response);GO:0001816(cytokine production);GO:0030593(neutrophil chemotaxis);GO:0070062(extracellular exosome);GO:0031012(extracellular matrix);GO:0061844(antimicrobial humoral immune response mediated by antimicrobial peptide);GO:0043312(neutrophil degranulation);GO:0004871(signal transducer activity);GO:0007267(cell-cell signaling);GO:0051092(positive regulation of NF-kappaB transcription factor activity);GO:0002224(toll-like receptor signaling pathway);GO:0034774(secretory granule lumen);GO:0019730(antimicrobial humoral response);GO:0050729(positive regulation of inflammatory response);GO:2001244(positive regulation of intrinsic apoptotic signaling pathway);GO:0030307(positive regulation of cell growth);GO:0006919(activation of cysteine-type endopeptidase activity involved in apoptotic process);GO:0051493(regulation of cytoskeleton organization);GO:0032602(chemokine production);GO:0016209(antioxidant activity);GO:0035821(modification of morphology or physiology of other organism);GO:0050832(defense response to fungus);GO:0050786(RAGE receptor binding);GO:0035606(peptidyl-cysteine S-trans-nitrosylation);GO:0035662(Toll-like receptor 4 binding);GO:0050544(arachidonic acid binding);GO:0002523(leukocyte migration involved in inflammatory response);GO:0032119(sequestering of zinc ion);GO:0070488(neutrophil aggregation)","04657(IL-17 signaling pathway)","K21128","NA","S100 calcium binding protein A9 [Source:HGNC Symbol;Acc:HGNC:10499]",{"v":436.776794,"d":"436.78"},{"v":1270.603027,"d":"1270.60"},{"v":0.343755511925126,"d":"0.34"},{"v":-1.54054524837858,"d":"-1.54"},{"v":0.0233391321311237,"d":"0.02"},{"v":0.479607216933433,"d":"0.48"},"down","yes"]
["ENSG00000162512","SDC3","ENST00000336798;ENST00000339394","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0050900(leukocyte migration);GO:0005886(plasma membrane);GO:0009986(cell surface);GO:0016477(cell migration);GO:0043202(lysosomal lumen);GO:0001523(retinoid metabolic process);GO:0006024(glycosaminoglycan biosynthetic process);GO:0006027(glycosaminoglycan catabolic process);GO:0030203(glycosaminoglycan metabolic process);GO:0005796(Golgi lumen);GO:0005796(Golgi lumen)","04514(Cell adhesion molecules (CAMs));04514(Cell adhesion molecules (CAMs))","K16337","NA","syndecan 3 [Source:HGNC Symbol;Acc:HGNC:10660]",{"v":0.138220641290505,"d":"0.14"},{"v":0.42738091693788,"d":"0.43"},{"v":0.323413226497886,"d":"0.32"},{"v":-1.62854941356276,"d":"-1.63"},{"v":0.0233802423029987,"d":"0.02"},{"v":0.479633522679234,"d":"0.48"},"down","yes"]
["MSTRG.3221","PLBD1","ENST00000541618;ENST00000240617;ENST00000541800;ENST00000540572","GO:0016787(hydrolase activity);GO:0006629(lipid metabolic process);GO:0016042(lipid catabolic process);GO:0005615(extracellular space);GO:0005764(lysosome);GO:0005829(cytosol);GO:0004623(phospholipase A2 activity);GO:0036149(phosphatidylinositol acyl-chain remodeling);GO:0036151(phosphatidylcholine acyl-chain remodeling);GO:0036152(phosphatidylethanolamine acyl-chain remodeling);GO:0004622(lysophospholipase activity);GO:0006644(phospholipid metabolic process);GO:0006644(phospholipid metabolic process)","NA","NA","NA","phospholipase B domain containing 1 [Source:HGNC Symbol;Acc:HGNC:26215]",{"v":21.4607686272439,"d":"21.46"},{"v":62.4227342917987,"d":"62.42"},{"v":0.343797317927861,"d":"0.34"},{"v":-1.54036980495,"d":"-1.54"},{"v":0.023473497319295,"d":"0.02"},{"v":0.480727644079848,"d":"0.48"},"down","yes"]
["MSTRG.7772","ZNF414","ENST00000255616;ENST00000600906;ENST00000602128;ENST00000593661;ENST00000596772;ENST00000393927;ENST00000595348","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0005515(protein binding)","NA","NA","NA","zinc finger protein 414 [Source:HGNC Symbol;Acc:HGNC:20630]",{"v":2.29515397425671,"d":"2.30"},{"v":0.799788733139957,"d":"0.80"},{"v":2.8697003085377,"d":"2.87"},{"v":1.52090007977128,"d":"1.52"},{"v":0.0235504911797607,"d":"0.02"},{"v":0.481043458087281,"d":"0.48"},"up","yes"]
["ENSG00000184207","PGP","ENST00000333503","GO:0046872(metal ion binding);GO:0016787(hydrolase activity);GO:0008152(metabolic process);GO:0016791(phosphatase activity);GO:0004721(phosphoprotein phosphatase activity);GO:0000287(magnesium ion binding);GO:0004725(protein tyrosine phosphatase activity);GO:0005975(carbohydrate metabolic process);GO:0005829(cytosol);GO:0000121(glycerol-1-phosphatase activity);GO:0008967(phosphoglycolate phosphatase activity);GO:0043136(glycerol-3-phosphatase activity);GO:0098519(nucleotide phosphatase activity, acting on free nucleotides);GO:0006114(glycerol biosynthetic process);GO:0006650(glycerophospholipid metabolic process);GO:0016311(dephosphorylation);GO:0035335(peptidyl-tyrosine dephosphorylation);GO:0045721(negative regulation of gluconeogenesis)","00630(Glyoxylate and dicarboxylate metabolism)","K19269","EC:3.1.3.18;EC:3.1.3.48","phosphoglycolate phosphatase [Source:HGNC Symbol;Acc:HGNC:8909]",{"v":0.410261,"d":"0.41"},{"v":1.248178,"d":"1.25"},{"v":0.328687895476446,"d":"0.33"},{"v":-1.60520976733332,"d":"-1.61"},{"v":0.0235688125121654,"d":"0.02"},{"v":0.481043458087281,"d":"0.48"},"down","yes"]
["MSTRG.4617","AL135818.1","ENST00000553725;ENST00000554096","NA","NA","NA","NA",null,{"v":1.34230751931106,"d":"1.34"},{"v":0.451427699373695,"d":"0.45"},{"v":2.97347176784535,"d":"2.97"},{"v":1.57214837785541,"d":"1.57"},{"v":0.0237112390876788,"d":"0.02"},{"v":0.483131541613921,"d":"0.48"},"up","yes"]
["MSTRG.5582","AC108134.3","ENST00000574387;ENST00000577123;ENST00000571404","NA","NA","NA","NA",null,{"v":1.38736737782805,"d":"1.39"},{"v":4.15303399245852,"d":"4.15"},{"v":0.334061165968631,"d":"0.33"},{"v":-1.58181581326444,"d":"-1.58"},{"v":0.0238331502679322,"d":"0.02"},{"v":0.484795262713581,"d":"0.48"},"down","yes"]
["MSTRG.5467","DDX11L9","ENST00000559159;ENST00000562189","NA","NA","NA","NA","DEAD/H-box helicase 11 like 9 [Source:HGNC Symbol;Acc:HGNC:37109]",{"v":6.30324831034483,"d":"6.30"},{"v":2.23057478850575,"d":"2.23"},{"v":2.82584038106489,"d":"2.83"},{"v":1.4986799766592,"d":"1.50"},{"v":0.0239371935624218,"d":"0.02"},{"v":0.48609053099272,"d":"0.49"},"up","yes"]
["ENSG00000279407","AC007191.1","ENST00000623179","NA","NA","NA","NA",null,{"v":1.257305,"d":"1.26"},{"v":0.434739,"d":"0.43"},{"v":2.89209157678515,"d":"2.89"},{"v":1.53211323530496,"d":"1.53"},{"v":0.0240002945579378,"d":"0.02"},{"v":0.486551426038193,"d":"0.49"},"up","yes"]
["ENSG00000197928","ZNF677","ENST00000594681;ENST00000598513;ENST00000601413;ENST00000333952;ENST00000595293;ENST00000601828;ENST00000594517;ENST00000593539;ENST00000599328;ENST00000599012;ENST00000598806","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0005622(intracellular);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding)","NA","NA","NA","zinc finger protein 677 [Source:HGNC Symbol;Acc:HGNC:28730]",{"v":0.0755431501925546,"d":"0.08"},{"v":0.240255514120668,"d":"0.24"},{"v":0.314428372098104,"d":"0.31"},{"v":-1.66919669141795,"d":"-1.67"},{"v":0.024046559034079,"d":"0.02"},{"v":0.486670023341814,"d":"0.49"},"down","yes"]
["MSTRG.12863","LTB","ENST00000429299;ENST00000446745;ENST00000482429;ENST00000483972","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0006955(immune response);GO:0005125(cytokine activity);GO:0005615(extracellular space);GO:0005164(tumor necrosis factor receptor binding);GO:0005886(plasma membrane);GO:0005575(cellular_component);GO:0033209(tumor necrosis factor-mediated signaling pathway);GO:0007165(signal transduction);GO:0007267(cell-cell signaling);GO:0045084(positive regulation of interleukin-12 biosynthetic process);GO:0005102(receptor binding);GO:0010467(gene expression);GO:0043588(skin development);GO:0048535(lymph node development);GO:0048535(lymph node development)","04064(NF-kappa B signaling pathway);04060(Cytokine-cytokine receptor interaction);05323(Rheumatoid arthritis);05323(Rheumatoid arthritis)","K03157","NA","lymphotoxin beta [Source:HGNC Symbol;Acc:HGNC:6711]",{"v":27.2499484820847,"d":"27.25"},{"v":78.88085167557,"d":"78.88"},{"v":0.345457077392639,"d":"0.35"},{"v":-1.53342162618302,"d":"-1.53"},{"v":0.024133495822117,"d":"0.02"},{"v":0.487609994446195,"d":"0.49"},"down","yes"]
["ENSG00000125731","SH2D3A","ENST00000437152;ENST00000245908;ENST00000595681;ENST00000597687;ENST00000595369","GO:0005622(intracellular);GO:0007264(small GTPase mediated signal transduction);GO:0009967(positive regulation of signal transduction);GO:0043547(positive regulation of GTPase activity);GO:0005515(protein binding);GO:0005085(guanyl-nucleotide exchange factor activity);GO:0005070(SH3/SH2 adaptor activity);GO:0007254(JNK cascade);GO:0007254(JNK cascade)","NA","NA","NA","SH2 domain containing 3A [Source:HGNC Symbol;Acc:HGNC:16885]",{"v":1.20218579793562,"d":"1.20"},{"v":0.421478756298111,"d":"0.42"},{"v":2.85230460603646,"d":"2.85"},{"v":1.51212805967525,"d":"1.51"},{"v":0.0243228408183828,"d":"0.02"},{"v":0.489831482399088,"d":"0.49"},"up","yes"]
["MSTRG.14327","KAT6A","ENST00000406337;ENST00000418721;ENST00000396930;ENST00000265713;ENST00000485568;ENST00000426524;ENST00000470574","GO:0005634(nucleus);GO:0016607(nuclear speck);GO:0046872(metal ion binding);GO:0005730(nucleolus);GO:0005829(cytosol);GO:0016740(transferase activity);GO:0003713(transcription coactivator activity);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0016569(covalent chromatin modification);GO:0003677(DNA binding);GO:0016746(transferase activity, transferring acyl groups);GO:0006334(nucleosome assembly);GO:0000786(nucleosome);GO:0008270(zinc ion binding);GO:0005515(protein binding);GO:0016747(transferase activity, transferring acyl groups other than amino-acyl groups);GO:0004402(histone acetyltransferase activity);GO:0045893(positive regulation of transcription, DNA-templated);GO:0005654(nucleoplasm);GO:0070776(MOZ/MORF histone acetyltransferase complex);GO:0043966(histone H3 acetylation);GO:0048513(animal organ development);GO:0008134(transcription factor binding);GO:0045892(negative regulation of transcription, DNA-templated);GO:1901796(regulation of signal transduction by p53 class mediator);GO:0016605(PML body);GO:0006323(DNA packaging);GO:0090398(cellular senescence);GO:0030099(myeloid cell differentiation);GO:0016407(acetyltransferase activity);GO:0006473(protein acetylation);GO:0016573(histone acetylation);GO:0016573(histone acetylation)","04550(Signaling pathways regulating pluripotency of stem cells);04550(Signaling pathways regulating pluripotency of stem cells)","K11305","EC:2.3.1.48","lysine acetyltransferase 6A [Source:HGNC Symbol;Acc:HGNC:13013]",{"v":9.49670899375633,"d":"9.50"},{"v":3.4093685038812,"d":"3.41"},{"v":2.78547448976118,"d":"2.79"},{"v":1.4779231034066,"d":"1.48"},{"v":0.0243694962521301,"d":"0.02"},{"v":0.489831482399088,"d":"0.49"},"up","yes"]
["MSTRG.11597","TXK","ENST00000264316;ENST00000506073;ENST00000514937;ENST00000509681;ENST00000507351;ENST00000510457","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0006366(transcription from RNA polymerase II promoter);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0004713(protein tyrosine kinase activity);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0004715(non-membrane spanning protein tyrosine kinase activity);GO:0002376(immune system process);GO:0002250(adaptive immune response);GO:0001816(cytokine production);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:0060335(positive regulation of interferon-gamma-mediated signaling pathway);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0030154(cell differentiation);GO:0042127(regulation of cell proliferation);GO:0050852(T cell receptor signaling pathway);GO:0046777(protein autophosphorylation);GO:0001077(transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0038083(peptidyl-tyrosine autophosphorylation);GO:0031234(extrinsic component of cytoplasmic side of plasma membrane);GO:0007169(transmembrane receptor protein tyrosine kinase signaling pathway);GO:0007229(integrin-mediated signaling pathway);GO:0007202(activation of phospholipase C activity);GO:0032729(positive regulation of interferon-gamma production);GO:0010543(regulation of platelet activation);GO:0042246(tissue regeneration);GO:0001012(RNA polymerase II regulatory region DNA binding);GO:0018108(peptidyl-tyrosine phosphorylation);GO:0018108(peptidyl-tyrosine phosphorylation)","04670(Leukocyte transendothelial migration);04670(Leukocyte transendothelial migration)","K08016","EC:2.7.10.2","TXK tyrosine kinase [Source:HGNC Symbol;Acc:HGNC:12434]",{"v":9.55428155558756,"d":"9.55"},{"v":3.41863598732719,"d":"3.42"},{"v":2.79476422497308,"d":"2.79"},{"v":1.48272657794867,"d":"1.48"},{"v":0.0243918151033012,"d":"0.02"},{"v":0.489831482399088,"d":"0.49"},"up","yes"]
["MSTRG.10428","C1QTNF6","ENST00000493023;ENST00000397110;ENST00000467564;ENST00000497071;ENST00000337843;ENST00000434784;ENST00000470655","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0005581(collagen trimer);GO:0042802(identical protein binding);GO:0051259(protein oligomerization);GO:0070208(protein heterotrimerization);GO:0005615(extracellular space);GO:0005615(extracellular space)","NA","NA","NA","C1q and TNF related 6 [Source:HGNC Symbol;Acc:HGNC:14343]",{"v":0.409093149377012,"d":"0.41"},{"v":0.137560359932801,"d":"0.14"},{"v":2.97391741034159,"d":"2.97"},{"v":1.57236458237853,"d":"1.57"},{"v":0.0244061525859037,"d":"0.02"},{"v":0.489831482399088,"d":"0.49"},"up","yes"]
["ENSG00000179299","NSUN7","ENST00000381782;ENST00000463952","GO:0003723(RNA binding);GO:0008168(methyltransferase activity);GO:0016740(transferase activity);GO:0032259(methylation);GO:0032259(methylation)","NA","NA","NA","NOP2/Sun RNA methyltransferase family member 7 [Source:HGNC Symbol;Acc:HGNC:25857]",{"v":0.217223085448393,"d":"0.22"},{"v":0.655305466582064,"d":"0.66"},{"v":0.331483707256988,"d":"0.33"},{"v":-1.59299013265567,"d":"-1.59"},{"v":0.0246623960897882,"d":"0.02"},{"v":0.494150705013693,"d":"0.49"},"down","yes"]
["MSTRG.14691","RN7SL5P","ENST00000581458","NA","NA","NA","NA","RNA, 7SL, cytoplasmic 5, pseudogene [Source:HGNC Symbol;Acc:HGNC:10040]",{"v":180.60144,"d":"180.60"},{"v":64.965439,"d":"64.97"},{"v":2.77996181939138,"d":"2.78"},{"v":1.47506506879304,"d":"1.48"},{"v":0.0247530828143236,"d":"0.02"},{"v":0.495143892442001,"d":"0.50"},"up","yes"]
["MSTRG.1859","FAS","ENST00000355740;ENST00000479522;ENST00000352159;ENST00000640250;ENST00000477270;ENST00000484444;ENST00000488877;ENST00000466081;ENST00000460510;ENST00000371857;ENST00000357339;ENST00000494410;ENST00000492756;ENST00000494799;ENST00000313771;ENST00000640140;ENST00000612663","GO:0016020(membrane);GO:0005829(cytosol);GO:0007165(signal transduction);GO:0005886(plasma membrane);GO:0006915(apoptotic process);GO:0016604(nuclear body);GO:0006955(immune response);GO:0004888(transmembrane signaling receptor activity);GO:0016021(integral component of membrane);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0045121(membrane raft);GO:0042802(identical protein binding);GO:0005516(calmodulin binding);GO:0005739(mitochondrion);GO:0005887(integral component of plasma membrane);GO:0006954(inflammatory response);GO:0070062(extracellular exosome);GO:0004872(receptor activity);GO:0043065(positive regulation of apoptotic process);GO:0033209(tumor necrosis factor-mediated signaling pathway);GO:0042981(regulation of apoptotic process);GO:0004871(signal transducer activity);GO:0071260(cellular response to mechanical stimulus);GO:0097190(apoptotic signaling pathway);GO:0009986(cell surface);GO:0005031(tumor necrosis factor-activated receptor activity);GO:0006919(activation of cysteine-type endopeptidase activity involved in apoptotic process);GO:0007275(multicellular organism development);GO:0032496(response to lipopolysaccharide);GO:0042127(regulation of cell proliferation);GO:0097191(extrinsic apoptotic signaling pathway);GO:0097296(activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway);GO:1902041(regulation of extrinsic apoptotic signaling pathway via death domain receptors);GO:1902042(negative regulation of extrinsic apoptotic signaling pathway via death domain receptors);GO:0043066(negative regulation of apoptotic process);GO:0006461(protein complex assembly);GO:0031264(death-inducing signaling complex);GO:0019900(kinase binding);GO:0071455(cellular response to hyperoxia);GO:0097527(necroptotic signaling pathway);GO:0001934(positive regulation of protein phosphorylation);GO:0043120(tumor necrosis factor binding);GO:0002377(immunoglobulin production);GO:0003014(renal system process);GO:0006924(activation-induced cell death of T cells);GO:0006925(inflammatory cell apoptotic process);GO:0007623(circadian rhythm);GO:0008625(extrinsic apoptotic signaling pathway via death domain receptors);GO:0009636(response to toxic substance);GO:0010467(gene expression);GO:0019724(B cell mediated immunity);GO:0032464(positive regulation of protein homooligomerization);GO:0032872(regulation of stress-activated MAPK cascade);GO:0034198(cellular response to amino acid starvation);GO:0036337(Fas signaling pathway);GO:0043029(T cell homeostasis);GO:0045060(negative thymic T cell selection);GO:0045619(regulation of lymphocyte differentiation);GO:0045637(regulation of myeloid cell differentiation);GO:0048536(spleen development);GO:0050869(negative regulation of B cell activation);GO:0051260(protein homooligomerization);GO:0051384(response to glucocorticoid);GO:0051402(neuron apoptotic process);GO:0070230(positive regulation of lymphocyte apoptotic process);GO:0071285(cellular response to lithium ion);GO:0097049(motor neuron apoptotic process);GO:0097192(extrinsic apoptotic signaling pathway in absence of ligand);GO:0097284(hepatocyte apoptotic process);GO:2001235(positive regulation of apoptotic signaling pathway);GO:2001238(positive regulation of extrinsic apoptotic signaling pathway);GO:2001241(positive regulation of extrinsic apoptotic signaling pathway in absence of ligand);GO:2001269(positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway);GO:0009897(external side of plasma membrane);GO:0031265(CD95 death-inducing signaling complex);GO:0031265(CD95 death-inducing signaling complex)","04010(MAPK signaling pathway);04668(TNF signaling pathway);04060(Cytokine-cytokine receptor interaction);04210(Apoptosis);04217(Necroptosis);04115(p53 signaling pathway);04650(Natural killer cell mediated cytotoxicity);05200(Pathways in cancer);05205(Proteoglycans in cancer);05320(Autoimmune thyroid disease);05330(Allograft rejection);05332(Graft-versus-host disease);05010(Alzheimer's disease);04940(Type I diabetes mellitus);04932(Non-alcoholic fatty liver disease (NAFLD));05162(Measles);05164(Influenza A);05161(Hepatitis B);05168(Herpes simplex infection);05167(Kaposi's sarcoma-associated herpesvirus infection);05165(Human papillomavirus infection);05142(Chagas disease (American trypanosomiasis));05143(African trypanosomiasis);01524(Platinum drug resistance);01524(Platinum drug resistance)","K04390","NA","Fas cell surface death receptor [Source:HGNC Symbol;Acc:HGNC:11920]",{"v":1.64518727674583,"d":"1.65"},{"v":4.78681599858923,"d":"4.79"},{"v":0.343691355011494,"d":"0.34"},{"v":-1.54081453133224,"d":"-1.54"},{"v":0.0249147320096277,"d":"0.02"},{"v":0.497550916848982,"d":"0.50"},"down","yes"]
["MSTRG.1749","SRGN","MSTRG.1749.1;MSTRG.1749.4;ENST00000242465;ENST00000462445;MSTRG.1749.3;MSTRG.1749.2","GO:0005794(Golgi apparatus);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0006915(apoptotic process);GO:0005615(extracellular space);GO:0031214(biomineral tissue development);GO:0002576(platelet degranulation);GO:0031093(platelet alpha granule lumen);GO:0008626(granzyme-mediated apoptotic signaling pathway);GO:0030502(negative regulation of bone mineralization);GO:0016485(protein processing);GO:0005518(collagen binding);GO:0033364(mast cell secretory granule organization);GO:0033368(protease localization to mast cell secretory granule);GO:0033371(T cell secretory granule organization);GO:0033373(maintenance of protease location in mast cell secretory granule);GO:0033382(maintenance of granzyme B location in T cell secretory granule);GO:0050710(negative regulation of cytokine secretion);GO:0000139(Golgi membrane);GO:0042588(zymogen granule);GO:0042629(mast cell granule);GO:0042629(mast cell granule)","NA","NA","NA","serglycin [Source:HGNC Symbol;Acc:HGNC:9361]",{"v":121.058635201371,"d":"121.06"},{"v":347.684920269909,"d":"347.68"},{"v":0.348184888511681,"d":"0.35"},{"v":-1.52207450459894,"d":"-1.52"},{"v":0.0250104041079096,"d":"0.03"},{"v":0.498085249067547,"d":"0.50"},"down","yes"]
["ENSG00000167702","KIFC2","ENST00000301332;ENST00000529644;ENST00000533114;ENST00000529864;ENST00000531425","GO:0005737(cytoplasm);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0003777(microtubule motor activity);GO:0005856(cytoskeleton);GO:0008017(microtubule binding);GO:0005874(microtubule);GO:0007018(microtubule-based movement);GO:0016887(ATPase activity);GO:0005871(kinesin complex);GO:0005871(kinesin complex)","NA","NA","NA","kinesin family member C2 [Source:HGNC Symbol;Acc:HGNC:29530]",{"v":1.86822960445244,"d":"1.87"},{"v":0.664914104340005,"d":"0.66"},{"v":2.80973074906698,"d":"2.81"},{"v":1.4904318864614,"d":"1.49"},{"v":0.0250242132275258,"d":"0.03"},{"v":0.498085249067547,"d":"0.50"},"up","yes"]
["ENSG00000171970","ZNF57","ENST00000614108;ENST00000306908;ENST00000590305","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0005622(intracellular);GO:0005622(intracellular)","NA","NA","NA","zinc finger protein 57 [Source:HGNC Symbol;Acc:HGNC:13125]",{"v":0.325055017619252,"d":"0.33"},{"v":0.995040819939837,"d":"1.00"},{"v":0.326675058053303,"d":"0.33"},{"v":-1.61407178702436,"d":"-1.61"},{"v":0.0251841440302721,"d":"0.03"},{"v":0.498326407812253,"d":"0.50"},"down","yes"]
["MSTRG.2882","CD3G","ENST00000532917;ENST00000292144;ENST00000528540;ENST00000527777;ENST00000533462;ENST00000532903","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0015031(protein transport);GO:0004888(transmembrane signaling receptor activity);GO:0007166(cell surface receptor signaling pathway);GO:0038096(Fc-gamma receptor signaling pathway involved in phagocytosis);GO:0050776(regulation of immune response);GO:0005886(plasma membrane);GO:0005887(integral component of plasma membrane);GO:0061024(membrane organization);GO:0050852(T cell receptor signaling pathway);GO:0042105(alpha-beta T cell receptor complex);GO:0046982(protein heterodimerization activity);GO:0042110(T cell activation);GO:0006461(protein complex assembly);GO:0031295(T cell costimulation);GO:0042803(protein homodimerization activity);GO:0051260(protein homooligomerization);GO:0030665(clathrin-coated vesicle membrane);GO:0030159(receptor signaling complex scaffold activity);GO:0007163(establishment or maintenance of cell polarity);GO:0042101(T cell receptor complex);GO:0042608(T cell receptor binding);GO:0070228(regulation of lymphocyte apoptotic process);GO:0070228(regulation of lymphocyte apoptotic process)","04640(Hematopoietic cell lineage);04660(T cell receptor signaling pathway);04658(Th1 and Th2 cell differentiation);04659(Th17 cell differentiation);05166(HTLV-I infection);05162(Measles);05142(Chagas disease (American trypanosomiasis));05142(Chagas disease (American trypanosomiasis))","K06452","NA","CD3g molecule [Source:HGNC Symbol;Acc:HGNC:1675]",{"v":13.4958475951512,"d":"13.50"},{"v":4.86472129066736,"d":"4.86"},{"v":2.77422832445552,"d":"2.77"},{"v":1.47208652919147,"d":"1.47"},{"v":0.0251928704794933,"d":"0.03"},{"v":0.498326407812253,"d":"0.50"},"up","yes"]
["MSTRG.10627","ARL8B","ENST00000611208;ENST00000256496;ENST00000444332;ENST00000476343;ENST00000455168;ENST00000468010","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005525(GTP binding);GO:0007264(small GTPase mediated signal transduction);GO:0000166(nucleotide binding);GO:0005622(intracellular);GO:0005765(lysosomal membrane);GO:0051301(cell division);GO:0005856(cytoskeleton);GO:0007049(cell cycle);GO:0003924(GTPase activity);GO:0005764(lysosome);GO:0005819(spindle);GO:0030496(midbody);GO:0007059(chromosome segregation);GO:0005515(protein binding);GO:0005768(endosome);GO:0031902(late endosome membrane);GO:0070062(extracellular exosome);GO:0051233(spindle midzone);GO:0043014(alpha-tubulin binding);GO:0019003(GDP binding);GO:0048487(beta-tubulin binding);GO:0032418(lysosome localization);GO:0032418(lysosome localization)","NA","NA","NA","ADP ribosylation factor like GTPase 8B [Source:HGNC Symbol;Acc:HGNC:25564]",{"v":2.43388693092841,"d":"2.43"},{"v":7.04243012807606,"d":"7.04"},{"v":0.345603277088293,"d":"0.35"},{"v":-1.53281119736106,"d":"-1.53"},{"v":0.0252287253679282,"d":"0.03"},{"v":0.498326407812253,"d":"0.50"},"down","yes"]
["MSTRG.6750","AC244154.1","ENST00000620148","NA","NA","NA","NA",null,{"v":1.522679,"d":"1.52"},{"v":4.457908,"d":"4.46"},{"v":0.341568062867157,"d":"0.34"},{"v":-1.54975500780125,"d":"-1.55"},{"v":0.0252897264583559,"d":"0.03"},{"v":0.498326407812253,"d":"0.50"},"down","yes"]
["MSTRG.907","PLEKHO1","ENST00000369124;ENST00000607609;ENST00000479194;ENST00000485470;ENST00000492304;ENST00000369126;ENST00000477309;ENST00000441340;ENST00000502767","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0007520(myoblast fusion);GO:0008360(regulation of cell shape);GO:0051451(myoblast migration);GO:0072673(lamellipodium morphogenesis);GO:0032587(ruffle membrane);GO:0036195(muscle cell projection membrane);GO:0036195(muscle cell projection membrane)","NA","NA","NA","pleckstrin homology domain containing O1 [Source:HGNC Symbol;Acc:HGNC:24310]",{"v":5.21627980563595,"d":"5.22"},{"v":14.9821241453161,"d":"14.98"},{"v":0.348166905776624,"d":"0.35"},{"v":-1.52214901751873,"d":"-1.52"},{"v":0.0253007097021853,"d":"0.03"},{"v":0.498326407812253,"d":"0.50"},"down","yes"]
["MSTRG.8136","PLEKHG2","ENST00000425673;ENST00000594307;ENST00000451354;ENST00000596443;ENST00000458508;ENST00000474449;ENST00000478523","GO:0005089(Rho guanyl-nucleotide exchange factor activity);GO:0035023(regulation of Rho protein signal transduction);GO:0043547(positive regulation of GTPase activity);GO:0005085(guanyl-nucleotide exchange factor activity);GO:0005829(cytosol);GO:0051056(regulation of small GTPase mediated signal transduction);GO:0043065(positive regulation of apoptotic process);GO:0030833(regulation of actin filament polymerization);GO:0030833(regulation of actin filament polymerization)","NA","NA","NA","pleckstrin homology and RhoGEF domain containing G2 [Source:HGNC Symbol;Acc:HGNC:29515]",{"v":2.97158472521739,"d":"2.97"},{"v":1.0699810475,"d":"1.07"},{"v":2.77723117821616,"d":"2.78"},{"v":1.47364727286596,"d":"1.47"},{"v":0.0253213342459303,"d":"0.03"},{"v":0.498326407812253,"d":"0.50"},"up","yes"]
["MSTRG.14151","AC144652.1","ENST00000609974","NA","NA","NA","NA",null,{"v":0.372116,"d":"0.37"},{"v":1.176369,"d":"1.18"},{"v":0.316325914742738,"d":"0.32"},{"v":-1.66051634257509,"d":"-1.66"},{"v":0.0253260057782012,"d":"0.03"},{"v":0.498326407812253,"d":"0.50"},"down","yes"]
["MSTRG.12376","CYSTM1","ENST00000261811;ENST00000509789;ENST00000504227;ENST00000509589","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005886(plasma membrane);GO:0003674(molecular_function);GO:0008150(biological_process);GO:0070062(extracellular exosome);GO:0043312(neutrophil degranulation);GO:0070821(tertiary granule membrane);GO:0070821(tertiary granule membrane)","NA","NA","NA","cysteine rich transmembrane module containing 1 [Source:HGNC Symbol;Acc:HGNC:30239]",{"v":9.13361037299771,"d":"9.13"},{"v":26.1745117620137,"d":"26.17"},{"v":0.34895055373117,"d":"0.35"},{"v":-1.51890547375541,"d":"-1.52"},{"v":0.0256159260124186,"d":"0.03"},{"v":0.503069028953395,"d":"0.50"},"down","yes"]
["MSTRG.11710","HSD17B11;AC108516.2;HSD17B13","ENST00000358290;ENST00000508163;ENST00000513854;ENST00000328546;ENST00000508413;ENST00000507286;ENST00000502576;ENST00000507518;ENST00000512344","GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0006629(lipid metabolic process);GO:0006694(steroid biosynthetic process);GO:0005811(lipid particle);GO:0005576(extracellular region);GO:0005829(cytosol);GO:0004303(estradiol 17-beta-dehydrogenase activity);GO:0006703(estrogen biosynthetic process);GO:0005737(cytoplasm);GO:0016229(steroid dehydrogenase activity);GO:0006710(androgen catabolic process);GO:0003674(molecular_function);GO:0008150(biological_process);GO:0005575(cellular_component);GO:0034389(lipid particle organization);GO:0046889(positive regulation of lipid biosynthetic process);GO:0006710(androgen catabolic process)","NA","NA","NA","hydroxysteroid 17-beta dehydrogenase 11 [Source:HGNC Symbol;Acc:HGNC:22960];hydroxysteroid 17-beta dehydrogenase 13 [Source:HGNC Symbol;Acc:HGNC:18685]",{"v":3.88889458261934,"d":"3.89"},{"v":11.154670130763,"d":"11.15"},{"v":0.348633759405786,"d":"0.35"},{"v":-1.52021581753759,"d":"-1.52"},{"v":0.0256505882558865,"d":"0.03"},{"v":0.503069028953395,"d":"0.50"},"down","yes"]
["ENSG00000178338","ZNF354B","ENST00000522714;ENST00000522624;ENST00000520377;ENST00000322434","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0005622(intracellular);GO:0003682(chromatin binding);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0000122(negative regulation of transcription from RNA polymerase II promoter)","NA","NA","NA","zinc finger protein 354B [Source:HGNC Symbol;Acc:HGNC:17197]",{"v":0.556526297333333,"d":"0.56"},{"v":0.186527575733333,"d":"0.19"},{"v":2.98361405891515,"d":"2.98"},{"v":1.57706092992983,"d":"1.58"},{"v":0.0258689664080648,"d":"0.03"},{"v":0.505457083649095,"d":"0.51"},"up","yes"]
["MSTRG.7072","VMP1","ENST00000585847;ENST00000591877;ENST00000587470;ENST00000592790;MSTRG.7072.11;ENST00000262291;ENST00000593168;ENST00000588915;ENST00000587259;ENST00000591315;ENST00000588617;ENST00000589823;ENST00000586245;ENST00000592619;ENST00000588131;ENST00000592106;ENST00000591782","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005783(endoplasmic reticulum);GO:0005730(nucleolus);GO:0007155(cell adhesion);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0006914(autophagy);GO:0000421(autophagosome membrane);GO:0000407(pre-autophagosomal structure);GO:0007030(Golgi organization);GO:0005773(vacuole);GO:0005774(vacuolar membrane);GO:0006887(exocytosis);GO:0016337(single organismal cell-cell adhesion);GO:0033116(endoplasmic reticulum-Golgi intermediate compartment membrane);GO:0034329(cell junction assembly);GO:0007029(endoplasmic reticulum organization);GO:0007566(embryo implantation);GO:0007566(embryo implantation)","04140(Autophagy - animal);04140(Autophagy - animal)","K21248","NA","vacuole membrane protein 1 [Source:HGNC Symbol;Acc:HGNC:29559]",{"v":19.3758211777968,"d":"19.38"},{"v":55.3183115964612,"d":"55.32"},{"v":0.350260530710708,"d":"0.35"},{"v":-1.51349966842619,"d":"-1.51"},{"v":0.0258815188687038,"d":"0.03"},{"v":0.505457083649095,"d":"0.51"},"down","yes"]
["MSTRG.15326","ALAS2","ENST00000498636;ENST00000335854;ENST00000330807;ENST00000396198;MSTRG.15326.2;MSTRG.15326.1;ENST00000455688;ENST00000493869;ENST00000477869;ENST00000463868","GO:0016740(transferase activity);GO:0005743(mitochondrial inner membrane);GO:0003824(catalytic activity);GO:0016746(transferase activity, transferring acyl groups);GO:0008152(metabolic process);GO:0009058(biosynthetic process);GO:0005739(mitochondrion);GO:0005515(protein binding);GO:0030170(pyridoxal phosphate binding);GO:0006783(heme biosynthetic process);GO:0030218(erythrocyte differentiation);GO:0005759(mitochondrial matrix);GO:0006879(cellular iron ion homeostasis);GO:0033014(tetrapyrrole biosynthetic process);GO:0006782(protoporphyrinogen IX biosynthetic process);GO:0001666(response to hypoxia);GO:0003870(5-aminolevulinate synthase activity);GO:0006778(porphyrin-containing compound metabolic process);GO:0016594(glycine binding);GO:0050662(coenzyme binding);GO:0042541(hemoglobin biosynthetic process);GO:0032364(oxygen homeostasis);GO:0032364(oxygen homeostasis)","00260(Glycine, serine and threonine metabolism);00860(Porphyrin and chlorophyll metabolism);00860(Porphyrin and chlorophyll metabolism)","K00643","EC:2.3.1.37","5'-aminolevulinate synthase 2 [Source:HGNC Symbol;Acc:HGNC:397]",{"v":435.522339572298,"d":"435.52"},{"v":158.364166184839,"d":"158.36"},{"v":2.75013186419942,"d":"2.75"},{"v":1.45950079509754,"d":"1.46"},{"v":0.025936512174073,"d":"0.03"},{"v":0.505457083649095,"d":"0.51"},"up","yes"]
["ENSG00000255036","AL512590.3","ENST00000534123;ENST00000375206;ENST00000529787;ENST00000532526","NA","NA","NA","NA",null,{"v":0.480355598229342,"d":"0.48"},{"v":0.1679640757448,"d":"0.17"},{"v":2.85987105337442,"d":"2.86"},{"v":1.51595009985293,"d":"1.52"},{"v":0.0259402489366501,"d":"0.03"},{"v":0.505457083649095,"d":"0.51"},"up","yes"]
["ENSG00000099810","MTAP","ENST00000380172;ENST00000427788;ENST00000580900;ENST00000581962;ENST00000577563;ENST00000460874","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0016740(transferase activity);GO:0009116(nucleoside metabolic process);GO:0003824(catalytic activity);GO:0016757(transferase activity, transferring glycosyl groups);GO:0005515(protein binding);GO:0016763(transferase activity, transferring pentosyl groups);GO:0070062(extracellular exosome);GO:0017061(S-methyl-5-thioadenosine phosphorylase activity);GO:0006166(purine ribonucleoside salvage);GO:0019509(L-methionine salvage from methylthioadenosine);GO:0006139(nucleobase-containing compound metabolic process);GO:0035722(interleukin-12-mediated signaling pathway);GO:0004645(phosphorylase activity);GO:0004731(purine-nucleoside phosphorylase activity);GO:0004731(purine-nucleoside phosphorylase activity)","00270(Cysteine and methionine metabolism);00270(Cysteine and methionine metabolism)","K00772","EC:2.4.2.28","methylthioadenosine phosphorylase [Source:HGNC Symbol;Acc:HGNC:7413]",{"v":0.422894451050147,"d":"0.42"},{"v":0.150448972087296,"d":"0.15"},{"v":2.81088295375503,"d":"2.81"},{"v":1.49102338059379,"d":"1.49"},{"v":0.0261219996972913,"d":"0.03"},{"v":0.507217649758311,"d":"0.51"},"up","yes"]
["MSTRG.11604","DANCR","ENST00000441504;ENST00000444958;ENST00000411630;ENST00000623036;ENST00000425653","NA","NA","NA","NA","differentiation antagonizing non-protein coding RNA [Source:HGNC Symbol;Acc:HGNC:28964]",{"v":0.476412517724289,"d":"0.48"},{"v":1.4270914809628,"d":"1.43"},{"v":0.333834602812479,"d":"0.33"},{"v":-1.58279459339644,"d":"-1.58"},{"v":0.0261386738742875,"d":"0.03"},{"v":0.507217649758311,"d":"0.51"},"down","yes"]
["ENSG00000157107","FCHO2","ENST00000430046;ENST00000511264;ENST00000508431;ENST00000503302","GO:0016020(membrane);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0005905(clathrin-coated pit);GO:0035091(phosphatidylinositol binding);GO:0072583(clathrin-dependent endocytosis);GO:0005829(cytosol);GO:0006897(endocytosis);GO:0061024(membrane organization);GO:0005546(phosphatidylinositol-4,5-bisphosphate binding);GO:0048268(clathrin coat assembly);GO:0030136(clathrin-coated vesicle);GO:0001786(phosphatidylserine binding);GO:0010324(membrane invagination);GO:0072659(protein localization to plasma membrane);GO:0048488(synaptic vesicle endocytosis);GO:0098835(presynaptic endocytic zone membrane);GO:0098835(presynaptic endocytic zone membrane)","NA","NA","NA","FCH domain only 2 [Source:HGNC Symbol;Acc:HGNC:25180]",{"v":0.889902354496491,"d":"0.89"},{"v":2.5547597065448,"d":"2.55"},{"v":0.348331137451688,"d":"0.35"},{"v":-1.52146865314479,"d":"-1.52"},{"v":0.0261569640009891,"d":"0.03"},{"v":0.507217649758311,"d":"0.51"},"down","yes"]
["ENSG00000213186","TRIM59","ENST00000309784;ENST00000479460;ENST00000471396;ENST00000496222;ENST00000543469;ENST00000494486;ENST00000468542","GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0005622(intracellular);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016567(protein ubiquitination);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005515(protein binding);GO:0005813(centrosome);GO:0060271(cilium assembly);GO:0005929(cilium);GO:0030992(intraciliary transport particle B);GO:0043124(negative regulation of I-kappaB kinase/NF-kappaB signaling);GO:0061630(ubiquitin protein ligase activity);GO:0045087(innate immune response);GO:0046597(negative regulation of viral entry into host cell);GO:0046597(negative regulation of viral entry into host cell)","NA","NA","NA","tripartite motif containing 59 [Source:HGNC Symbol;Acc:HGNC:30834]",{"v":0.358697610425938,"d":"0.36"},{"v":0.12425500546726,"d":"0.12"},{"v":2.88678600171525,"d":"2.89"},{"v":1.52946416413532,"d":"1.53"},{"v":0.0262678409530679,"d":"0.03"},{"v":0.508548779351839,"d":"0.51"},"up","yes"]
["ENSG00000170456","DENND5B","ENST00000389082;ENST00000536562;ENST00000546299;ENST00000354285;ENST00000537061","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0043547(positive regulation of GTPase activity);GO:0070588(calcium ion transmembrane transport);GO:0005085(guanyl-nucleotide exchange factor activity);GO:0005829(cytosol);GO:0017112(Rab guanyl-nucleotide exchange factor activity);GO:0061024(membrane organization);GO:0005262(calcium channel activity);GO:0050982(detection of mechanical stimulus);GO:0050982(detection of mechanical stimulus)","NA","NA","NA","DENN domain containing 5B [Source:HGNC Symbol;Acc:HGNC:28338]",{"v":0.41850371556145,"d":"0.42"},{"v":0.148502933863837,"d":"0.15"},{"v":2.8181511615466,"d":"2.82"},{"v":1.49474899779546,"d":"1.49"},{"v":0.0263748142021004,"d":"0.03"},{"v":0.509377503133126,"d":"0.51"},"up","yes"]
["MSTRG.12463","DCTN4","ENST00000447998;ENST00000522625;ENST00000521728;ENST00000627368;ENST00000519313;ENST00000518015;ENST00000518909;ENST00000424236;ENST00000520195;ENST00000517421;ENST00000521093","GO:0005737(cytoplasm);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0005813(centrosome);GO:0005815(microtubule organizing center);GO:0005869(dynactin complex);GO:0005829(cytosol);GO:0019886(antigen processing and presentation of exogenous peptide antigen via MHC class II);GO:0005634(nucleus);GO:0047485(protein N-terminus binding);GO:0006888(ER to Golgi vesicle-mediated transport);GO:0005868(cytoplasmic dynein complex);GO:0007097(nuclear migration);GO:0007097(nuclear migration)","04962(Vasopressin-regulated water reabsorption);05016(Huntington's disease);05016(Huntington's disease)","K10426","NA","dynactin subunit 4 [Source:HGNC Symbol;Acc:HGNC:15518]",{"v":1.48745170048309,"d":"1.49"},{"v":4.25784692504286,"d":"4.26"},{"v":0.349343629930547,"d":"0.35"},{"v":-1.51728126104765,"d":"-1.52"},{"v":0.0263952467991256,"d":"0.03"},{"v":0.509377503133126,"d":"0.51"},"down","yes"]
["MSTRG.12810","AL671277.1;ZNRD1ASP","ENST00000429656;MSTRG.12810.1","NA","NA","NA","NA",null,{"v":6.24789503920118,"d":"6.25"},{"v":17.8573062892012,"d":"17.86"},{"v":0.34987892003507,"d":"0.35"},{"v":-1.51507234907781,"d":"-1.52"},{"v":0.0265825161821236,"d":"0.03"},{"v":0.512170655784212,"d":"0.51"},"down","yes"]
["MSTRG.6321","CYB5D2","ENST00000575251;ENST00000301391;ENST00000575411;ENST00000577075","GO:0005576(extracellular region);GO:0007399(nervous system development);GO:0012505(endomembrane system);GO:0016020(membrane);GO:0020037(heme binding);GO:0045666(positive regulation of neuron differentiation);GO:0045666(positive regulation of neuron differentiation)","NA","NA","NA","cytochrome b5 domain containing 2 [Source:HGNC Symbol;Acc:HGNC:28471]",{"v":0.317470164069661,"d":"0.32"},{"v":0.964773448212649,"d":"0.96"},{"v":0.329061879405792,"d":"0.33"},{"v":-1.60356918959696,"d":"-1.60"},{"v":0.0266483868557713,"d":"0.03"},{"v":0.51226325669568,"d":"0.51"},"down","yes"]
["ENSG00000162241","SLC25A45","ENST00000531791;ENST00000398802;ENST00000527174;ENST00000529962;ENST00000534028;ENST00000534338;ENST00000533629;ENST00000526432;ENST00000525944;ENST00000294187;ENST00000526259;ENST00000524438;ENST00000529431;ENST00000530936;ENST00000526898","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0055085(transmembrane transport);GO:0005743(mitochondrial inner membrane);GO:0005739(mitochondrion);GO:0006839(mitochondrial transport);GO:0022857(transmembrane transporter activity);GO:0022857(transmembrane transporter activity)","NA","NA","NA","solute carrier family 25 member 45 [Source:HGNC Symbol;Acc:HGNC:27442]",{"v":2.05573299745385,"d":"2.06"},{"v":0.741058652959898,"d":"0.74"},{"v":2.77404897607355,"d":"2.77"},{"v":1.47199325879154,"d":"1.47"},{"v":0.0267268057244926,"d":"0.03"},{"v":0.51226325669568,"d":"0.51"},"up","yes"]
["MSTRG.7803","PDE4A","ENST00000293683;ENST00000592685;ENST00000586275;ENST00000440014;ENST00000590407;ENST00000380702;ENST00000589073","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0046872(metal ion binding);GO:0005654(nucleoplasm);GO:0016787(hydrolase activity);GO:0007165(signal transduction);GO:0005886(plasma membrane);GO:0042995(cell projection);GO:0048471(perinuclear region of cytoplasm);GO:0008081(phosphoric diester hydrolase activity);GO:0004114(3',5'-cyclic-nucleotide phosphodiesterase activity);GO:0005515(protein binding);GO:0005829(cytosol);GO:0032587(ruffle membrane);GO:0004115(3',5'-cyclic-AMP phosphodiesterase activity);GO:0006198(cAMP catabolic process);GO:0030552(cAMP binding);GO:0007608(sensory perception of smell);GO:0010738(regulation of protein kinase A signaling);GO:0035690(cellular response to drug);GO:0043949(regulation of cAMP-mediated signaling);GO:0043949(regulation of cAMP-mediated signaling)","00230(Purine metabolism);04024(cAMP signaling pathway);05032(Morphine addiction);05032(Morphine addiction)","K13293","EC:3.1.4.53","phosphodiesterase 4A [Source:HGNC Symbol;Acc:HGNC:8780]",{"v":1.49642137044839,"d":"1.50"},{"v":0.537561634968402,"d":"0.54"},{"v":2.78372055054924,"d":"2.78"},{"v":1.47701439057883,"d":"1.48"},{"v":0.0267692397201596,"d":"0.03"},{"v":0.51226325669568,"d":"0.51"},"up","yes"]
["MSTRG.14930","MEGF9","ENST00000373930","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0008150(biological_process);GO:0005575(cellular_component);GO:0005604(basement membrane)","NA","NA","NA","multiple EGF like domains 9 [Source:HGNC Symbol;Acc:HGNC:3234]",{"v":13.962758,"d":"13.96"},{"v":39.597458,"d":"39.60"},{"v":0.352617534186159,"d":"0.35"},{"v":-1.50382387929205,"d":"-1.50"},{"v":0.0268183824701456,"d":"0.03"},{"v":0.51226325669568,"d":"0.51"},"down","yes"]
["ENSG00000019991","HGF","ENST00000222390;ENST00000457544;ENST00000453018;ENST00000444829;ENST00000354224;ENST00000421558;ENST00000423064;ENST00000412881","GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0030335(positive regulation of cell migration);GO:0043154(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process);GO:1901299(negative regulation of hydrogen peroxide-mediated programmed cell death);GO:0014068(positive regulation of phosphatidylinositol 3-kinase signaling);GO:0016020(membrane);GO:0018108(peptidyl-tyrosine phosphorylation);GO:0008083(growth factor activity);GO:0043547(positive regulation of GTPase activity);GO:0005515(protein binding);GO:0005615(extracellular space);GO:0005576(extracellular region);GO:0046854(phosphatidylinositol phosphorylation);GO:0050918(positive chemotaxis);GO:0000165(MAPK cascade);GO:0010507(negative regulation of autophagy);GO:0050731(positive regulation of peptidyl-tyrosine phosphorylation);GO:0002576(platelet degranulation);GO:0045669(positive regulation of osteoblast differentiation);GO:0031093(platelet alpha granule lumen);GO:0046934(phosphatidylinositol-4,5-bisphosphate 3-kinase activity);GO:0014066(regulation of phosphatidylinositol 3-kinase signaling);GO:0038111(interleukin-7-mediated signaling pathway);GO:0048015(phosphatidylinositol-mediated signaling);GO:0005088(Ras guanyl-nucleotide exchange factor activity);GO:0004713(protein tyrosine kinase activity);GO:0000278(mitotic cell cycle);GO:0035729(cellular response to hepatocyte growth factor stimulus);GO:0048012(hepatocyte growth factor receptor signaling pathway);GO:0090201(negative regulation of release of cytochrome c from mitochondria);GO:2000573(positive regulation of DNA biosynthetic process);GO:0042056(chemoattractant activity);GO:0060326(cell chemotaxis);GO:0008284(positive regulation of cell proliferation);GO:0046982(protein heterodimerization activity);GO:0000187(activation of MAPK activity);GO:0000902(cell morphogenesis);GO:0001837(epithelial to mesenchymal transition);GO:0001889(liver development);GO:0008283(cell proliferation);GO:0030212(hyaluronan metabolic process);GO:0031100(animal organ regeneration);GO:0031643(positive regulation of myelination);GO:0032715(negative regulation of interleukin-6 production);GO:0032733(positive regulation of interleukin-10 production);GO:0033137(negative regulation of peptidyl-serine phosphorylation);GO:0043066(negative regulation of apoptotic process);GO:0045766(positive regulation of angiogenesis);GO:0050728(negative regulation of inflammatory response);GO:0051450(myoblast proliferation);GO:0060665(regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling);GO:0070572(positive regulation of neuron projection regeneration);GO:1900744(regulation of p38MAPK cascade);GO:1902042(negative regulation of extrinsic apoptotic signaling pathway via death domain receptors);GO:1902947(regulation of tau-protein kinase activity);GO:1902947(regulation of tau-protein kinase activity)","04014(Ras signaling pathway);04015(Rap1 signaling pathway);04010(MAPK signaling pathway);04151(PI3K-Akt signaling pathway);04060(Cytokine-cytokine receptor interaction);04510(Focal adhesion);05200(Pathways in cancer);05205(Proteoglycans in cancer);05225(Hepatocellular carcinoma);05226(Gastric cancer);05218(Melanoma);05211(Renal cell carcinoma);05144(Malaria);01521(EGFR tyrosine kinase inhibitor resistance);01521(EGFR tyrosine kinase inhibitor resistance)","K05460","NA","hepatocyte growth factor [Source:HGNC Symbol;Acc:HGNC:4893]",{"v":0.193389459031134,"d":"0.19"},{"v":0.569871781499382,"d":"0.57"},{"v":0.339356089052716,"d":"0.34"},{"v":-1.55912819531115,"d":"-1.56"},{"v":0.0268244445337453,"d":"0.03"},{"v":0.51226325669568,"d":"0.51"},"down","yes"]
["MSTRG.661","GIPC2;DNAJB4","ENST00000370759;ENST00000370763;ENST00000484662;ENST00000476882;ENST00000487931;ENST00000477671;ENST00000426517","GO:0005737(cytoplasm);GO:0005515(protein binding);GO:0042802(identical protein binding);GO:0003674(molecular_function);GO:0008150(biological_process);GO:0070062(extracellular exosome);GO:0031982(vesicle);GO:0016020(membrane);GO:0005829(cytosol);GO:0006457(protein folding);GO:0005886(plasma membrane);GO:0032781(positive regulation of ATPase activity);GO:0051082(unfolded protein binding);GO:0051087(chaperone binding);GO:0006986(response to unfolded protein);GO:0001671(ATPase activator activity);GO:0009408(response to heat);GO:0009408(response to heat)","NA","NA","NA","GIPC PDZ domain containing family member 2 [Source:HGNC Symbol;Acc:HGNC:18177];DnaJ heat shock protein family (Hsp40) member B4 [Source:HGNC Symbol;Acc:HGNC:14886]",{"v":0.160316969262829,"d":"0.16"},{"v":0.470815313232613,"d":"0.47"},{"v":0.340509250139071,"d":"0.34"},{"v":-1.55423410443709,"d":"-1.55"},{"v":0.0268664645540251,"d":"0.03"},{"v":0.51226325669568,"d":"0.51"},"down","yes"]
["ENSG00000196586","MYO6","ENST00000369981;ENST00000369985","GO:0006810(transport);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0015031(protein transport);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0003774(motor activity);GO:0016459(myosin complex);GO:0005794(Golgi apparatus);GO:0003779(actin binding);GO:0005886(plasma membrane);GO:0042995(cell projection);GO:0005515(protein binding);GO:0048471(perinuclear region of cytoplasm);GO:0031410(cytoplasmic vesicle);GO:0005905(clathrin-coated pit);GO:0005654(nucleoplasm);GO:0006886(intracellular protein transport);GO:0005516(calmodulin binding);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0005829(cytosol);GO:0045296(cadherin binding);GO:0006897(endocytosis);GO:0051015(actin filament binding);GO:0070062(extracellular exosome);GO:0031941(filamentous actin);GO:0005938(cell cortex);GO:0032587(ruffle membrane);GO:0007605(sensory perception of sound);GO:0016461(unconventional myosin complex);GO:0001726(ruffle);GO:0031965(nuclear membrane);GO:0030665(clathrin-coated vesicle membrane);GO:0005765(lysosomal membrane);GO:0030330(DNA damage response, signal transduction by p53 class mediator);GO:0030139(endocytic vesicle);GO:0030048(actin filament-based movement);GO:0016591(DNA-directed RNA polymerase II, holoenzyme);GO:0043531(ADP binding);GO:0045334(clathrin-coated endocytic vesicle);GO:0060001(minus-end directed microfilament motor activity);GO:0051046(regulation of secretion);GO:0042493(response to drug);GO:0005902(microvillus);GO:0043231(intracellular membrane-bounded organelle);GO:0043234(protein complex);GO:0045177(apical part of cell);GO:0045177(apical part of cell)","NA","NA","NA","myosin VI [Source:HGNC Symbol;Acc:HGNC:7605]",{"v":0.35422641457029,"d":"0.35"},{"v":0.124734405008537,"d":"0.12"},{"v":2.83984530608092,"d":"2.84"},{"v":1.5058123444383,"d":"1.51"},{"v":0.0268851003348007,"d":"0.03"},{"v":0.51226325669568,"d":"0.51"},"up","yes"]
["MSTRG.8805","TEX261;AC007040.2","ENST00000272438;ENST00000433258;ENST00000478068;ENST00000473055;ENST00000489894;ENST00000606025;ENST00000466731","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0030176(integral component of endoplasmic reticulum membrane);GO:0030173(integral component of Golgi membrane);GO:0006888(ER to Golgi vesicle-mediated transport);GO:0030134(ER to Golgi transport vesicle);GO:0097020(COPII adaptor activity);GO:0097020(COPII adaptor activity)","NA","NA","NA","testis expressed 261 [Source:HGNC Symbol;Acc:HGNC:30712]",{"v":6.15201156701653,"d":"6.15"},{"v":2.24718319797322,"d":"2.25"},{"v":2.73765466587911,"d":"2.74"},{"v":1.45294047316808,"d":"1.45"},{"v":0.0269933524072081,"d":"0.03"},{"v":0.513513348637598,"d":"0.51"},"up","yes"]
["ENSG00000103550","KNOP1","ENST00000219837;ENST00000564480;ENST00000565844;ENST00000568230","GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005730(nucleolus);GO:0005730(nucleolus)","NA","NA","NA","lysine rich nucleolar protein 1 [Source:HGNC Symbol;Acc:HGNC:34404]",{"v":0.684747816003092,"d":"0.68"},{"v":0.241826520551475,"d":"0.24"},{"v":2.83156625849619,"d":"2.83"},{"v":1.50160028920584,"d":"1.50"},{"v":0.0270909334229602,"d":"0.03"},{"v":0.514556814320642,"d":"0.51"},"up","yes"]
["MSTRG.15033","TOR1A","ENST00000351698;ENST00000474192;ENST00000473084;MSTRG.15033.1;ENST00000473604","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0043231(intracellular membrane-bounded organelle);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0016787(hydrolase activity);GO:0031965(nuclear membrane);GO:0007155(cell adhesion);GO:0005783(endoplasmic reticulum);GO:0005856(cytoskeleton);GO:0042995(cell projection);GO:0005515(protein binding);GO:0031175(neuron projection development);GO:0008092(cytoskeletal protein binding);GO:0030054(cell junction);GO:0045202(synapse);GO:0030659(cytoplasmic vesicle membrane);GO:0031410(cytoplasmic vesicle);GO:0051082(unfolded protein binding);GO:0006998(nuclear envelope organization);GO:0045104(intermediate filament cytoskeleton organization);GO:0005635(nuclear envelope);GO:0005788(endoplasmic reticulum lumen);GO:0005829(cytosol);GO:0030426(growth cone);GO:0070062(extracellular exosome);GO:0016887(ATPase activity);GO:0061077(chaperone-mediated protein folding);GO:0019894(kinesin binding);GO:0051787(misfolded protein binding);GO:0000338(protein deneddylation);GO:0006979(response to oxidative stress);GO:0006996(organelle organization);GO:0034504(protein localization to nucleus);GO:0044319(wound healing, spreading of cells);GO:0048489(synaptic vesicle transport);GO:0051085(chaperone mediated protein folding requiring cofactor);GO:0051260(protein homooligomerization);GO:0051584(regulation of dopamine uptake involved in synaptic transmission);GO:0071712(ER-associated misfolded protein catabolic process);GO:0071763(nuclear membrane organization);GO:0072321(chaperone-mediated protein transport);GO:1900244(positive regulation of synaptic vesicle endocytosis);GO:2000008(regulation of protein localization to cell surface);GO:0008021(synaptic vesicle);GO:0030133(transport vesicle);GO:0030141(secretory granule);GO:0042406(extrinsic component of endoplasmic reticulum membrane);GO:0043005(neuron projection);GO:0043005(neuron projection)","NA","NA","NA","torsin family 1 member A [Source:HGNC Symbol;Acc:HGNC:3098]",{"v":1.75659844091669,"d":"1.76"},{"v":5.01173028407734,"d":"5.01"},{"v":0.350497401366059,"d":"0.35"},{"v":-1.51252434694304,"d":"-1.51"},{"v":0.0271546141575187,"d":"0.03"},{"v":0.514954116039118,"d":"0.51"},"down","yes"]
["MSTRG.4674","SLC25A29;AL157871.6","ENST00000554912;ENST00000556868;ENST00000555051;ENST00000555888;ENST00000392908;ENST00000556873;ENST00000553574;ENST00000555475;ENST00000555949;ENST00000556201;ENST00000359232;ENST00000556844;ENST00000557438;ENST00000553954;ENST00000556505","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0055085(transmembrane transport);GO:0005743(mitochondrial inner membrane);GO:0005739(mitochondrion);GO:1990822(basic amino acid transmembrane transport);GO:1903826(arginine transmembrane transport);GO:0015171(amino acid transmembrane transporter activity);GO:0006839(mitochondrial transport);GO:1902616(acyl carnitine transmembrane transport);GO:0006865(amino acid transport);GO:0015174(basic amino acid transmembrane transporter activity);GO:0005289(high-affinity arginine transmembrane transporter activity);GO:0005292(high-affinity lysine transmembrane transporter activity);GO:0015227(acyl carnitine transmembrane transporter activity);GO:0006844(acyl carnitine transport);GO:0015822(ornithine transport);GO:0089709(L-histidine transmembrane transport);GO:1903400(L-arginine transmembrane transport);GO:1903401(L-lysine transmembrane transport);GO:1990575(mitochondrial L-ornithine transmembrane transport);GO:1990575(mitochondrial L-ornithine transmembrane transport)","NA","NA","NA","solute carrier family 25 member 29 [Source:HGNC Symbol;Acc:HGNC:20116]",{"v":2.09073047763959,"d":"2.09"},{"v":0.755063005821646,"d":"0.76"},{"v":2.76894836791069,"d":"2.77"},{"v":1.46933815227701,"d":"1.47"},{"v":0.0273698956264697,"d":"0.03"},{"v":0.518220570965328,"d":"0.52"},"up","yes"]
["MSTRG.13600","TRGV3","ENST00000390346","GO:0005886(plasma membrane);GO:0006955(immune response);GO:0042605(peptide antigen binding);GO:0042287(MHC protein binding)","NA","NA","NA","T-cell receptor gamma variable 3 [Source:HGNC Symbol;Acc:HGNC:12288]",{"v":5.805349,"d":"5.81"},{"v":2.047748,"d":"2.05"},{"v":2.8349919033006,"d":"2.83"},{"v":1.50334461485542,"d":"1.50"},{"v":0.0274304810048956,"d":"0.03"},{"v":0.518552358337446,"d":"0.52"},"up","yes"]
["ENSG00000163644","PPM1K","ENST00000608933;ENST00000511506;ENST00000513546;ENST00000295908;ENST00000514204;ENST00000506423;ENST00000505022;ENST00000510548;ENST00000509340;ENST00000508256","GO:0046872(metal ion binding);GO:0016787(hydrolase activity);GO:0005739(mitochondrion);GO:0003824(catalytic activity);GO:0006470(protein dephosphorylation);GO:0004721(phosphoprotein phosphatase activity);GO:0005515(protein binding);GO:0005759(mitochondrial matrix);GO:0004722(protein serine/threonine phosphatase activity);GO:0043169(cation binding);GO:0009083(branched-chain amino acid catabolic process);GO:0009083(branched-chain amino acid catabolic process)","NA","NA","NA","protein phosphatase, Mg2+/Mn2+ dependent 1K [Source:HGNC Symbol;Acc:HGNC:25415]",{"v":2.0306879615689,"d":"2.03"},{"v":0.741013290299886,"d":"0.74"},{"v":2.74042043260396,"d":"2.74"},{"v":1.45439724701857,"d":"1.45"},{"v":0.0276068781086082,"d":"0.03"},{"v":0.518776408683437,"d":"0.52"},"up","yes"]
["MSTRG.8886","CD8A","ENST00000283635;ENST00000352580;ENST00000409511","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005886(plasma membrane);GO:0005576(extracellular region);GO:0006955(immune response);GO:0002376(immune system process);GO:0002250(adaptive immune response);GO:0050776(regulation of immune response);GO:0005887(integral component of plasma membrane);GO:0005515(protein binding);GO:0007166(cell surface receptor signaling pathway);GO:0042110(T cell activation);GO:0007169(transmembrane receptor protein tyrosine kinase signaling pathway);GO:0042288(MHC class I protein binding);GO:0015026(coreceptor activity);GO:0009897(external side of plasma membrane);GO:0042101(T cell receptor complex);GO:0002456(T cell mediated immunity);GO:0019882(antigen processing and presentation);GO:0045065(cytotoxic T cell differentiation);GO:0044853(plasma membrane raft);GO:0019901(protein kinase binding);GO:0042803(protein homodimerization activity);GO:0050850(positive regulation of calcium-mediated signaling);GO:0051607(defense response to virus);GO:0009986(cell surface);GO:0009986(cell surface)","04514(Cell adhesion molecules (CAMs));04640(Hematopoietic cell lineage);04612(Antigen processing and presentation);04660(T cell receptor signaling pathway);05340(Primary immunodeficiency);05340(Primary immunodeficiency)","K06458","NA","CD8a molecule [Source:HGNC Symbol;Acc:HGNC:1706]",{"v":37.9484040715465,"d":"37.95"},{"v":13.9498206298844,"d":"13.95"},{"v":2.72035068252064,"d":"2.72"},{"v":1.44379264240292,"d":"1.44"},{"v":0.0276118507344205,"d":"0.03"},{"v":0.518776408683437,"d":"0.52"},"up","yes"]
["MSTRG.7407","RAB31","ENST00000578921;ENST00000578734;ENST00000581109;ENST00000583137;ENST00000577796;ENST00000580361;ENST00000577284;ENST00000583921;ENST00000578737;ENST00000435762","GO:0016020(membrane);GO:0005525(GTP binding);GO:0000166(nucleotide binding);GO:0003924(GTPase activity);GO:0005794(Golgi apparatus);GO:0031410(cytoplasmic vesicle);GO:0005886(plasma membrane);GO:0005768(endosome);GO:0005829(cytosol);GO:0030670(phagocytic vesicle membrane);GO:0061024(membrane organization);GO:0005769(early endosome);GO:0043312(neutrophil degranulation);GO:0019003(GDP binding);GO:0030667(secretory granule membrane);GO:0032869(cellular response to insulin stimulus);GO:0032588(trans-Golgi network membrane);GO:0045335(phagocytic vesicle);GO:0031623(receptor internalization);GO:0031901(early endosome membrane);GO:0045055(regulated exocytosis);GO:0090382(phagosome maturation);GO:0043001(Golgi to plasma membrane protein transport);GO:0043001(Golgi to plasma membrane protein transport)","04144(Endocytosis);04144(Endocytosis)","K07891","NA","RAB31, member RAS oncogene family [Source:HGNC Symbol;Acc:HGNC:9771]",{"v":14.0283184418188,"d":"14.03"},{"v":39.5537992817759,"d":"39.55"},{"v":0.354664247089969,"d":"0.35"},{"v":-1.49547419214674,"d":"-1.50"},{"v":0.0276704941193559,"d":"0.03"},{"v":0.518776408683437,"d":"0.52"},"down","yes"]
["ENSG00000062524","LTK","ENST00000263800;ENST00000355166;ENST00000561619;ENST00000453182;ENST00000569283;ENST00000563518","GO:0005622(intracellular);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0004713(protein tyrosine kinase activity);GO:0007169(transmembrane receptor protein tyrosine kinase signaling pathway);GO:0018108(peptidyl-tyrosine phosphorylation);GO:0005515(protein binding);GO:0004714(transmembrane receptor protein tyrosine kinase activity);GO:0008283(cell proliferation);GO:0005887(integral component of plasma membrane);GO:0005886(plasma membrane);GO:0043066(negative regulation of apoptotic process);GO:0007165(signal transduction);GO:0014065(phosphatidylinositol 3-kinase signaling);GO:0010976(positive regulation of neuron projection development);GO:0071300(cellular response to retinoic acid);GO:0010666(positive regulation of cardiac muscle cell apoptotic process);GO:0010666(positive regulation of cardiac muscle cell apoptotic process)","NA","NA","NA","leukocyte receptor tyrosine kinase [Source:HGNC Symbol;Acc:HGNC:6721]",{"v":1.39990679398281,"d":"1.40"},{"v":0.497980178796562,"d":"0.50"},{"v":2.81116970833232,"d":"2.81"},{"v":1.49117055082924,"d":"1.49"},{"v":0.0276748768321409,"d":"0.03"},{"v":0.518776408683437,"d":"0.52"},"up","yes"]
["MSTRG.950","ZNF687","ENST00000324048;ENST00000336715;ENST00000443959;ENST00000436614;ENST00000459919;ENST00000426871","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0005515(protein binding)","NA","NA","NA","zinc finger protein 687 [Source:HGNC Symbol;Acc:HGNC:29277]",{"v":2.12564668656481,"d":"2.13"},{"v":6.02581368577729,"d":"6.03"},{"v":0.352756788943204,"d":"0.35"},{"v":-1.50325424656392,"d":"-1.50"},{"v":0.0277009825459791,"d":"0.03"},{"v":0.518776408683437,"d":"0.52"},"down","yes"]
["ENSG00000204131","NHSL2","ENST00000633930;ENST00000373677;ENST00000632230;ENST00000623354;ENST00000639939;ENST00000631833;ENST00000631375;ENST00000510661","GO:0030154(cell differentiation);GO:0030154(cell differentiation)","NA","NA","NA","NHS like 2 [Source:HGNC Symbol;Acc:HGNC:33737]",{"v":1.88099149000339,"d":"1.88"},{"v":5.30452377708122,"d":"5.30"},{"v":0.354601387240533,"d":"0.35"},{"v":-1.49572991465436,"d":"-1.50"},{"v":0.0277273805225756,"d":"0.03"},{"v":0.518776408683437,"d":"0.52"},"down","yes"]
["ENSG00000102057","KCND1","ENST00000218176;ENST00000376477","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0055085(transmembrane transport);GO:0046872(metal ion binding);GO:0005216(ion channel activity);GO:0006811(ion transport);GO:0005244(voltage-gated ion channel activity);GO:0005249(voltage-gated potassium channel activity);GO:0005267(potassium channel activity);GO:0006813(potassium ion transport);GO:0034765(regulation of ion transmembrane transport);GO:0051260(protein homooligomerization);GO:0071805(potassium ion transmembrane transport);GO:0008076(voltage-gated potassium channel complex);GO:0042995(cell projection);GO:0030425(dendrite);GO:0005886(plasma membrane);GO:0005575(cellular_component);GO:0061337(cardiac conduction);GO:0005250(A-type (transient outward) potassium channel activity);GO:0043025(neuronal cell body);GO:0043025(neuronal cell body)","NA","NA","NA","potassium voltage-gated channel subfamily D member 1 [Source:HGNC Symbol;Acc:HGNC:6237]",{"v":0.106629953676597,"d":"0.11"},{"v":0.32957351386258,"d":"0.33"},{"v":0.323539208071974,"d":"0.32"},{"v":-1.62798753919684,"d":"-1.63"},{"v":0.0277746032097075,"d":"0.03"},{"v":0.518776408683437,"d":"0.52"},"down","yes"]
["MSTRG.4436","PSMA3-AS1;C14orf37","ENST00000554360;ENST00000557660;ENST00000555275;MSTRG.4436.8;ENST00000554378;ENST00000557412;ENST00000267485;ENST00000554218;ENST00000555707;ENST00000551597;ENST00000554309;ENST00000553657;ENST00000556400;ENST00000556002;ENST00000555037;ENST00000555162","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016021(integral component of membrane)","NA","NA","NA","PSMA3 antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:26445];chromosome 14 open reading frame 37 [Source:HGNC Symbol;Acc:HGNC:19846]",{"v":2.71077056511107,"d":"2.71"},{"v":0.993315598600639,"d":"0.99"},{"v":2.72901237927799,"d":"2.73"},{"v":1.44837893894421,"d":"1.45"},{"v":0.0277869775453261,"d":"0.03"},{"v":0.518776408683437,"d":"0.52"},"up","yes"]
["ENSG00000152455","SUV39H2","ENST00000313519;ENST00000354919;ENST00000378325;ENST00000378331;ENST00000420416;ENST00000433779","GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0018024(histone-lysine N-methyltransferase activity);GO:0034968(histone lysine methylation);GO:0008270(zinc ion binding);GO:0008168(methyltransferase activity);GO:0016740(transferase activity);GO:0032259(methylation);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0016569(covalent chromatin modification);GO:0005694(chromosome);GO:0005515(protein binding);GO:0007049(cell cycle);GO:0048511(rhythmic process);GO:0030154(cell differentiation);GO:0000775(chromosome, centromeric region);GO:0005654(nucleoplasm);GO:0045892(negative regulation of transcription, DNA-templated);GO:0000785(chromatin);GO:0006338(chromatin remodeling);GO:0000976(transcription regulatory region sequence-specific DNA binding);GO:0042754(negative regulation of circadian rhythm);GO:0046974(histone methyltransferase activity (H3-K9 specific));GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0036123(histone H3-K9 dimethylation);GO:0036124(histone H3-K9 trimethylation);GO:0071456(cellular response to hypoxia);GO:1904047(S-adenosyl-L-methionine binding);GO:0006333(chromatin assembly or disassembly);GO:0006333(chromatin assembly or disassembly)","00310(Lysine degradation);00310(Lysine degradation)","K11419","EC:2.1.1.43","suppressor of variegation 3-9 homolog 2 [Source:HGNC Symbol;Acc:HGNC:17287]",{"v":0.167560591304348,"d":"0.17"},{"v":0.525162902103787,"d":"0.53"},{"v":0.319064028767274,"d":"0.32"},{"v":-1.64808212633377,"d":"-1.65"},{"v":0.0279904291177597,"d":"0.03"},{"v":0.52135707529004,"d":"0.52"},"down","yes"]
["MSTRG.9788","NCOA5","ENST00000290231;ENST00000372291","GO:0003723(RNA binding);GO:0005634(nucleus);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0015629(actin cytoskeleton);GO:0005515(protein binding);GO:0005615(extracellular space);GO:0003682(chromatin binding);GO:0042593(glucose homeostasis);GO:0046627(negative regulation of insulin receptor signaling pathway);GO:0046627(negative regulation of insulin receptor signaling pathway)","NA","NA","NA","nuclear receptor coactivator 5 [Source:HGNC Symbol;Acc:HGNC:15909]",{"v":11.307524421118,"d":"11.31"},{"v":4.15906993354037,"d":"4.16"},{"v":2.71876275268413,"d":"2.72"},{"v":1.44295026299944,"d":"1.44"},{"v":0.0280352425606537,"d":"0.03"},{"v":0.52135707529004,"d":"0.52"},"up","yes"]
["MSTRG.401","PHC2;MIR3605","MSTRG.401.3;ENST00000373418;MSTRG.401.1;ENST00000467894;ENST00000459964;ENST00000373422;ENST00000257118;MSTRG.401.8;ENST00000486897;ENST00000583214;ENST00000493483;ENST00000431992;ENST00000473158;ENST00000485928","GO:0005634(nucleus);GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0005654(nucleoplasm);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0007275(multicellular organism development);GO:0042802(identical protein binding);GO:0031519(PcG protein complex);GO:0035102(PRC1 complex);GO:0007283(spermatogenesis);GO:0000792(heterochromatin);GO:0005615(extracellular space);GO:0000792(heterochromatin)","NA","NA","NA","polyhomeotic homolog 2 [Source:HGNC Symbol;Acc:HGNC:3183];microRNA 3605 [Source:HGNC Symbol;Acc:HGNC:38922]",{"v":7.6396770683055,"d":"7.64"},{"v":21.5104199482079,"d":"21.51"},{"v":0.355161688460759,"d":"0.36"},{"v":-1.49345212932736,"d":"-1.49"},{"v":0.0280550892532757,"d":"0.03"},{"v":0.52135707529004,"d":"0.52"},"down","yes"]
["MSTRG.3569","OSBPL8","ENST00000611266;MSTRG.3569.1;ENST00000393250;ENST00000553139;ENST00000548535;ENST00000550865;ENST00000547544;ENST00000552178;ENST00000393249;ENST00000548485;ENST00000551927;ENST00000546946;ENST00000548341;ENST00000547540;ENST00000549570;ENST00000552586;ENST00000550628","GO:0051897(positive regulation of protein kinase B signaling);GO:0032148(activation of protein kinase B activity);GO:0006810(transport);GO:0005634(nucleus);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0006869(lipid transport);GO:0008289(lipid binding);GO:0005829(cytosol);GO:0031965(nuclear membrane);GO:0001786(phosphatidylserine binding);GO:0005548(phospholipid transporter activity);GO:0036150(phosphatidylserine acyl-chain remodeling);GO:0045444(fat cell differentiation);GO:0015914(phospholipid transport);GO:0070273(phosphatidylinositol-4-phosphate binding);GO:0015485(cholesterol binding);GO:2001275(positive regulation of glucose import in response to insulin stimulus);GO:0010891(negative regulation of sequestering of triglyceride);GO:0030336(negative regulation of cell migration);GO:0046628(positive regulation of insulin receptor signaling pathway);GO:0090204(protein localization to nuclear pore);GO:0090204(protein localization to nuclear pore)","NA","NA","NA","oxysterol binding protein like 8 [Source:HGNC Symbol;Acc:HGNC:16396]",{"v":6.37533889236791,"d":"6.38"},{"v":17.9156598792129,"d":"17.92"},{"v":0.355852864775863,"d":"0.36"},{"v":-1.49064724452792,"d":"-1.49"},{"v":0.0282823330362698,"d":"0.03"},{"v":0.523757289271539,"d":"0.52"},"down","yes"]
["ENSG00000122966","CIT","ENST00000392521;ENST00000544800;ENST00000538073;ENST00000545913;ENST00000541841;ENST00000469414","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0035556(intracellular signal transduction);GO:0051301(cell division);GO:0007049(cell cycle);GO:0007275(multicellular organism development);GO:0007399(nervous system development);GO:0030154(cell differentiation);GO:0005515(protein binding);GO:0005829(cytosol);GO:0017124(SH3 domain binding);GO:0017048(Rho GTPase binding);GO:0030165(PDZ domain binding);GO:0097110(scaffold protein binding);GO:0000086(G2/M transition of mitotic cell cycle);GO:0000278(mitotic cell cycle);GO:0000281(mitotic cytokinesis);GO:0000910(cytokinesis);GO:0007030(Golgi organization);GO:0008064(regulation of actin polymerization or depolymerization);GO:0032467(positive regulation of cytokinesis);GO:0048699(generation of neurons);GO:0051402(neuron apoptotic process);GO:0005886(plasma membrane);GO:0031985(Golgi cisterna);GO:0043025(neuronal cell body);GO:0005622(intracellular);GO:0005622(intracellular)","NA","NA","NA","citron rho-interacting serine/threonine kinase [Source:HGNC Symbol;Acc:HGNC:1985]",{"v":0.155853115646259,"d":"0.16"},{"v":0.0534018244142101,"d":"0.05"},{"v":2.91849796061999,"d":"2.92"},{"v":1.54522606009802,"d":"1.55"},{"v":0.0282837965409112,"d":"0.03"},{"v":0.523757289271539,"d":"0.52"},"up","yes"]
["MSTRG.9437","CNPPD1","ENST00000360507;ENST00000453038;ENST00000451647;ENST00000409789","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0019901(protein kinase binding);GO:0000079(regulation of cyclin-dependent protein serine/threonine kinase activity);GO:0000079(regulation of cyclin-dependent protein serine/threonine kinase activity)","NA","NA","NA","cyclin Pas1/PHO80 domain containing 1 [Source:HGNC Symbol;Acc:HGNC:25220]",{"v":13.8399347311594,"d":"13.84"},{"v":38.8741507282609,"d":"38.87"},{"v":0.356018960463051,"d":"0.36"},{"v":-1.4899740181968,"d":"-1.49"},{"v":0.0283419867854811,"d":"0.03"},{"v":0.523757289271539,"d":"0.52"},"down","yes"]
["MSTRG.313","XKR8","ENST00000373884;ENST00000481387","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005886(plasma membrane);GO:0006915(apoptotic process);GO:0043652(engulfment of apoptotic cell);GO:0070782(phosphatidylserine exposure on apoptotic cell surface);GO:0070782(phosphatidylserine exposure on apoptotic cell surface)","NA","NA","NA","XK related 8 [Source:HGNC Symbol;Acc:HGNC:25508]",{"v":7.21257942690485,"d":"7.21"},{"v":20.2889717987605,"d":"20.29"},{"v":0.355492604477152,"d":"0.36"},{"v":-1.49210854796846,"d":"-1.49"},{"v":0.028358225594174,"d":"0.03"},{"v":0.523757289271539,"d":"0.52"},"down","yes"]
["ENSG00000161267","BDH1","ENST00000392378;ENST00000468710;ENST00000483920;ENST00000492681;ENST00000434143;ENST00000477015;ENST00000446746;ENST00000495285;ENST00000445160;ENST00000392379;ENST00000432819","GO:0016020(membrane);GO:0005654(nucleoplasm);GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0005739(mitochondrion);GO:0005743(mitochondrial inner membrane);GO:0003824(catalytic activity);GO:0008152(metabolic process);GO:0005759(mitochondrial matrix);GO:0046951(ketone body biosynthetic process);GO:0046952(ketone body catabolic process);GO:0003858(3-hydroxybutyrate dehydrogenase activity);GO:0099617(matrix side of mitochondrial inner membrane);GO:0099617(matrix side of mitochondrial inner membrane)","00650(Butanoate metabolism);00072(Synthesis and degradation of ketone bodies);00072(Synthesis and degradation of ketone bodies)","K00019","EC:1.1.1.30","3-hydroxybutyrate dehydrogenase 1 [Source:HGNC Symbol;Acc:HGNC:1027]",{"v":0.526964876892693,"d":"0.53"},{"v":0.18497691529515,"d":"0.18"},{"v":2.84881427529411,"d":"2.85"},{"v":1.51036157011873,"d":"1.51"},{"v":0.0284862518186658,"d":"0.03"},{"v":0.525316147626912,"d":"0.53"},"up","yes"]
["MSTRG.1726","IPMK","ENST00000373935","GO:0005634(nucleus);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0005730(nucleolus);GO:0005654(nucleoplasm);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0008440(inositol-1,4,5-trisphosphate 3-kinase activity);GO:0043647(inositol phosphate metabolic process);GO:0000823(inositol-1,4,5-trisphosphate 6-kinase activity);GO:0000824(inositol tetrakisphosphate 3-kinase activity);GO:0000825(inositol tetrakisphosphate 6-kinase activity);GO:0047326(inositol tetrakisphosphate 5-kinase activity)","00562(Inositol phosphate metabolism);04070(Phosphatidylinositol signaling system)","K00915","EC:2.7.1.140;EC:2.7.1.151","inositol polyphosphate multikinase [Source:HGNC Symbol;Acc:HGNC:20739]",{"v":1.80815,"d":"1.81"},{"v":5.076179,"d":"5.08"},{"v":0.35620296289788,"d":"0.36"},{"v":-1.48922857805395,"d":"-1.49"},{"v":0.0287810518044956,"d":"0.03"},{"v":0.529941018088281,"d":"0.53"},"down","yes"]
["ENSG00000069188","SDK2","ENST00000392650;ENST00000585283;ENST00000479356","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0007155(cell adhesion);GO:0005886(plasma membrane);GO:0030054(cell junction);GO:0045202(synapse);GO:0010842(retina layer formation);GO:0007156(homophilic cell adhesion via plasma membrane adhesion molecules);GO:0060219(camera-type eye photoreceptor cell differentiation);GO:0007416(synapse assembly);GO:0045216(cell-cell junction organization);GO:0045216(cell-cell junction organization)","NA","NA","NA","sidekick cell adhesion molecule 2 [Source:HGNC Symbol;Acc:HGNC:19308]",{"v":0.621868477642802,"d":"0.62"},{"v":0.227605306022228,"d":"0.23"},{"v":2.73222311250543,"d":"2.73"},{"v":1.45007529847512,"d":"1.45"},{"v":0.0289567377561923,"d":"0.03"},{"v":0.532361887114607,"d":"0.53"},"up","yes"]
["MSTRG.11491","SLBP","ENST00000489418;ENST00000488267;ENST00000429429;ENST00000318386;ENST00000480936;ENST00000483348","GO:0003723(RNA binding);GO:0003729(mRNA binding);GO:0006397(mRNA processing);GO:0051028(mRNA transport);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005730(nucleolus);GO:0005829(cytosol);GO:0030529(intracellular ribonucleoprotein complex);GO:0005515(protein binding);GO:0005654(nucleoplasm);GO:0006369(termination of RNA polymerase II transcription);GO:0006406(mRNA export from nucleus);GO:0071204(histone pre-mRNA 3'end processing complex);GO:0044770(cell cycle phase transition);GO:0008334(histone mRNA metabolic process);GO:0071208(histone pre-mRNA DCP binding);GO:0006398(mRNA 3'-end processing by stem-loop binding and cleavage);GO:0071207(histone pre-mRNA stem-loop binding);GO:0033260(nuclear DNA replication);GO:0033260(nuclear DNA replication)","NA","NA","NA","stem-loop binding protein [Source:HGNC Symbol;Acc:HGNC:10904]",{"v":3.35061807008884,"d":"3.35"},{"v":9.4904180745311,"d":"9.49"},{"v":0.353052736325779,"d":"0.35"},{"v":-1.50204439650964,"d":"-1.50"},{"v":0.0291293313467317,"d":"0.03"},{"v":0.534602318136174,"d":"0.53"},"down","yes"]
["ENSG00000150456","EEF1AKMT1","ENST00000460374;ENST00000382758;ENST00000382754","GO:0003676(nucleic acid binding);GO:0005737(cytoplasm);GO:0008168(methyltransferase activity);GO:0016740(transferase activity);GO:0032259(methylation);GO:0016279(protein-lysine N-methyltransferase activity);GO:0018022(peptidyl-lysine methylation);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0006479(protein methylation);GO:0006479(protein methylation)","NA","NA","NA","EEF1A lysine methyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:27351]",{"v":1.43219312397311,"d":"1.43"},{"v":0.495649644510829,"d":"0.50"},{"v":2.88952718888073,"d":"2.89"},{"v":1.53083344495378,"d":"1.53"},{"v":0.029167391049283,"d":"0.03"},{"v":0.534602318136174,"d":"0.53"},"up","yes"]
["ENSG00000185189","NRBP2","ENST00000530347;ENST00000533093;ENST00000527545;ENST00000442628;ENST00000529747;ENST00000423469","GO:0005737(cytoplasm);GO:0004672(protein kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0007399(nervous system development);GO:0012505(endomembrane system);GO:0004674(protein serine/threonine kinase activity);GO:0035556(intracellular signal transduction);GO:0005829(cytosol);GO:0006888(ER to Golgi vesicle-mediated transport);GO:0043524(negative regulation of neuron apoptotic process);GO:0030182(neuron differentiation);GO:0016242(negative regulation of macroautophagy);GO:0016242(negative regulation of macroautophagy)","NA","NA","NA","nuclear receptor binding protein 2 [Source:HGNC Symbol;Acc:HGNC:19339]",{"v":1.58866841267262,"d":"1.59"},{"v":0.576471446994314,"d":"0.58"},{"v":2.7558492635773,"d":"2.76"},{"v":1.46249697924802,"d":"1.46"},{"v":0.0292177881721434,"d":"0.03"},{"v":0.53471216591026,"d":"0.53"},"up","yes"]
["MSTRG.3605","NUDT4","ENST00000415493;ENST00000337179;ENST00000550056;ENST00000548662;ENST00000547014;ENST00000546925;ENST00000549992","GO:0003723(RNA binding);GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0005829(cytosol);GO:0016787(hydrolase activity);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005622(intracellular);GO:0035556(intracellular signal transduction);GO:0043647(inositol phosphate metabolic process);GO:0019722(calcium-mediated signaling);GO:0046907(intracellular transport);GO:0000298(endopolyphosphatase activity);GO:0008486(diphosphoinositol-polyphosphate diphosphatase activity);GO:0034431(bis(5'-adenosyl)-hexaphosphatase activity);GO:0034432(bis(5'-adenosyl)-pentaphosphatase activity);GO:0050072(m7G(5')pppN diphosphatase activity);GO:0052840(inositol diphosphate tetrakisphosphate diphosphatase activity);GO:0052841(inositol bisdiphosphate tetrakisphosphate diphosphatase activity);GO:0052842(inositol diphosphate pentakisphosphate diphosphatase activity);GO:0052843(inositol-1-diphosphate-2,3,4,5,6-pentakisphosphate diphosphatase activity);GO:0052844(inositol-3-diphosphate-1,2,4,5,6-pentakisphosphate diphosphatase activity);GO:0052845(inositol-5-diphosphate-1,2,3,4,6-pentakisphosphate diphosphatase activity);GO:0052846(inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 1-diphosphatase activity);GO:0052847(inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity);GO:0052848(inositol-3,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity);GO:1901907(diadenosine pentaphosphate catabolic process);GO:1901909(diadenosine hexaphosphate catabolic process);GO:1901911(adenosine 5'-(hexahydrogen pentaphosphate) catabolic process);GO:0030515(snoRNA binding);GO:0046831(regulation of RNA export from nucleus);GO:0071543(diphosphoinositol polyphosphate metabolic process);GO:0009187(cyclic nucleotide metabolic process);GO:0019935(cyclic-nucleotide-mediated signaling);GO:0019935(cyclic-nucleotide-mediated signaling)","NA","NA","NA","nudix hydrolase 4 [Source:HGNC Symbol;Acc:HGNC:8051]",{"v":2.26639272772376,"d":"2.27"},{"v":0.837593909307402,"d":"0.84"},{"v":2.70583716349826,"d":"2.71"},{"v":1.43607502095443,"d":"1.44"},{"v":0.0293119466637111,"d":"0.03"},{"v":0.535177250177001,"d":"0.54"},"up","yes"]
["MSTRG.7102","PECAM1","ENST00000564866;MSTRG.7102.4;MSTRG.7102.1;MSTRG.7102.2;ENST00000563924;ENST00000569967;ENST00000568702;MSTRG.7102.6;ENST00000563523;ENST00000569530;MSTRG.7102.3","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0001525(angiogenesis);GO:0001886(endothelial cell morphogenesis);GO:0007266(Rho protein signal transduction);GO:0030334(regulation of cell migration);GO:0042060(wound healing);GO:0042531(positive regulation of tyrosine phosphorylation of STAT protein);GO:0043542(endothelial cell migration);GO:0090673(endothelial cell-matrix adhesion);GO:0005886(plasma membrane);GO:0009897(external side of plasma membrane);GO:0030485(smooth muscle contractile fiber);GO:0045121(membrane raft);GO:0071944(cell periphery);GO:0071944(cell periphery)","04514(Cell adhesion molecules (CAMs));04670(Leukocyte transendothelial migration);05418(Fluid shear stress and atherosclerosis);05144(Malaria);05144(Malaria)","K06471","NA","platelet and endothelial cell adhesion molecule 1 [Source:HGNC Symbol;Acc:HGNC:8823]",{"v":22.6325709067524,"d":"22.63"},{"v":63.0771863081075,"d":"63.08"},{"v":0.358807553593166,"d":"0.36"},{"v":-1.47871783278879,"d":"-1.48"},{"v":0.0293842903488291,"d":"0.03"},{"v":0.535177250177001,"d":"0.54"},"down","yes"]
["MSTRG.10880","LTF","ENST00000231751;ENST00000417439;ENST00000426532;ENST00000493056;ENST00000443496;ENST00000431944","GO:0006810(transport);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005615(extracellular space);GO:0046872(metal ion binding);GO:0016787(hydrolase activity);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0005576(extracellular region);GO:0006811(ion transport);GO:0005506(iron ion binding);GO:0005515(protein binding);GO:0008233(peptidase activity);GO:0006508(proteolysis);GO:0004252(serine-type endopeptidase activity);GO:0008236(serine-type peptidase activity);GO:0002376(immune system process);GO:0042742(defense response to bacterium);GO:0008201(heparin binding);GO:0070062(extracellular exosome);GO:0043539(protein serine/threonine kinase activator activity);GO:0050829(defense response to Gram-negative bacterium);GO:0071902(positive regulation of protein serine/threonine kinase activity);GO:0044267(cellular protein metabolic process);GO:0001895(retina homeostasis);GO:0043234(protein complex);GO:0001817(regulation of cytokine production);GO:0060349(bone morphogenesis);GO:0002227(innate immune response in mucosa);GO:0019731(antibacterial humoral response);GO:0061844(antimicrobial humoral immune response mediated by antimicrobial peptide);GO:0043312(neutrophil degranulation);GO:0043123(positive regulation of I-kappaB kinase/NF-kappaB signaling);GO:0019732(antifungal humoral response);GO:0001503(ossification);GO:0042581(specific granule);GO:0043066(negative regulation of apoptotic process);GO:0051092(positive regulation of NF-kappaB transcription factor activity);GO:0001530(lipopolysaccharide binding);GO:0009986(cell surface);GO:0019730(antimicrobial humoral response);GO:0035580(specific granule lumen);GO:1904724(tertiary granule lumen);GO:0031640(killing of cells of other organism);GO:0097013(phagocytic vesicle lumen);GO:0006959(humoral immune response);GO:0004869(cysteine-type endopeptidase inhibitor activity);GO:0044218(other organism cell membrane);GO:0055072(iron ion homeostasis);GO:0031665(negative regulation of lipopolysaccharide-mediated signaling pathway);GO:0032680(regulation of tumor necrosis factor production);GO:0032780(negative regulation of ATPase activity);GO:0033214(iron assimilation by chelation and transport);GO:0033690(positive regulation of osteoblast proliferation);GO:0034145(positive regulation of toll-like receptor 4 signaling pathway);GO:0044793(negative regulation by host of viral process);GO:0045071(negative regulation of viral genome replication);GO:0045669(positive regulation of osteoblast differentiation);GO:0048525(negative regulation of viral process);GO:0051673(membrane disruption in other organism);GO:1900159(positive regulation of bone mineralization involved in bone maturation);GO:1900229(negative regulation of single-species biofilm formation in or on host organism);GO:1902732(positive regulation of chondrocyte proliferation);GO:2000117(negative regulation of cysteine-type endopeptidase activity);GO:2000308(negative regulation of tumor necrosis factor (ligand) superfamily member 11 production);GO:2001205(negative regulation of osteoclast development);GO:0030141(secretory granule);GO:0030141(secretory granule)","NA","NA","NA","lactotransferrin [Source:HGNC Symbol;Acc:HGNC:6720]",{"v":6.79325836755357,"d":"6.79"},{"v":18.9754712759595,"d":"18.98"},{"v":0.358002089579726,"d":"0.36"},{"v":-1.48196008667853,"d":"-1.48"},{"v":0.029393015963869,"d":"0.03"},{"v":0.535177250177001,"d":"0.54"},"down","yes"]
["MSTRG.8237","PGLYRP1","ENST00000008938","GO:0008270(zinc ion binding);GO:0005576(extracellular region);GO:0002376(immune system process);GO:0045087(innate immune response);GO:0042742(defense response to bacterium);GO:0070062(extracellular exosome);GO:0002221(pattern recognition receptor signaling pathway);GO:0050830(defense response to Gram-positive bacterium);GO:0061844(antimicrobial humoral immune response mediated by antimicrobial peptide);GO:0043312(neutrophil degranulation);GO:0009253(peptidoglycan catabolic process);GO:0006955(immune response);GO:0019730(antimicrobial humoral response);GO:0035580(specific granule lumen);GO:1904724(tertiary granule lumen);GO:0031640(killing of cells of other organism);GO:0042834(peptidoglycan binding);GO:0008745(N-acetylmuramoyl-L-alanine amidase activity);GO:0016019(peptidoglycan receptor activity);GO:0016045(detection of bacterium);GO:0032689(negative regulation of interferon-gamma production);GO:0032827(negative regulation of natural killer cell differentiation involved in immune response);GO:0044117(growth of symbiont in host);GO:0050728(negative regulation of inflammatory response);GO:0051714(positive regulation of cytolysis in other organism);GO:0097013(phagocytic vesicle lumen)","NA","NA","NA","peptidoglycan recognition protein 1 [Source:HGNC Symbol;Acc:HGNC:8904]",{"v":4.596951,"d":"4.60"},{"v":13.025065,"d":"13.03"},{"v":0.352931137003923,"d":"0.35"},{"v":-1.50254137879771,"d":"-1.50"},{"v":0.0294209715676113,"d":"0.03"},{"v":0.535177250177001,"d":"0.54"},"down","yes"]
["MSTRG.8358","SIGLEC9","ENST00000250360;ENST00000440804;ENST00000599948;MSTRG.8358.1","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0030246(carbohydrate binding);GO:0007155(cell adhesion);GO:0050776(regulation of immune response);GO:0005886(plasma membrane);GO:0005887(integral component of plasma membrane);GO:0043312(neutrophil degranulation);GO:0030667(secretory granule membrane);GO:0007166(cell surface receptor signaling pathway);GO:0007166(cell surface receptor signaling pathway)","NA","NA","NA","sialic acid binding Ig like lectin 9 [Source:HGNC Symbol;Acc:HGNC:10878]",{"v":1.99491514862177,"d":"1.99"},{"v":5.56968428445581,"d":"5.57"},{"v":0.358173829383704,"d":"0.36"},{"v":-1.48126816682557,"d":"-1.48"},{"v":0.0296237453601052,"d":"0.03"},{"v":0.537394394418676,"d":"0.54"},"down","yes"]
["MSTRG.4385","PYGL","ENST00000216392;ENST00000530336;ENST00000553872;ENST00000544180;ENST00000532462;ENST00000528757;ENST00000532107","GO:0016740(transferase activity);GO:0016757(transferase activity, transferring glycosyl groups);GO:0005975(carbohydrate metabolic process);GO:0030170(pyridoxal phosphate binding);GO:0004645(phosphorylase activity);GO:0008184(glycogen phosphorylase activity);GO:0102499(-);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0042803(protein homodimerization activity);GO:0005515(protein binding);GO:0003824(catalytic activity);GO:0008152(metabolic process);GO:0005576(extracellular region);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0043312(neutrophil degranulation);GO:0034774(secretory granule lumen);GO:1904813(ficolin-1-rich granule lumen);GO:0008144(drug binding);GO:0005980(glycogen catabolic process);GO:0042593(glucose homeostasis);GO:0005977(glycogen metabolic process);GO:0002060(purine nucleobase binding);GO:0005536(glucose binding);GO:0016208(AMP binding);GO:0019842(vitamin binding);GO:0032052(bile acid binding);GO:0030246(carbohydrate binding);GO:0006015(5-phosphoribose 1-diphosphate biosynthetic process);GO:0070266(necroptotic process);GO:0070266(necroptotic process)","00500(Starch and sucrose metabolism);04217(Necroptosis);04910(Insulin signaling pathway);04922(Glucagon signaling pathway);04931(Insulin resistance);04931(Insulin resistance)","K00688","EC:2.4.1.1","glycogen phosphorylase L [Source:HGNC Symbol;Acc:HGNC:9725]",{"v":13.1715870060442,"d":"13.17"},{"v":36.6658962315548,"d":"36.67"},{"v":0.359232648313358,"d":"0.36"},{"v":-1.47700962170325,"d":"-1.48"},{"v":0.0296321107701379,"d":"0.03"},{"v":0.537394394418676,"d":"0.54"},"down","yes"]
["ENSG00000145012","LPP","ENST00000617246;ENST00000640853;ENST00000487347;ENST00000415906;ENST00000430340;ENST00000448637;ENST00000618621;ENST00000457242;ENST00000416784;ENST00000414139;ENST00000484468;ENST00000494233;ENST00000459897","GO:0005829(cytosol);GO:0005925(focal adhesion);GO:0046872(metal ion binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0007155(cell adhesion);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0030054(cell junction);GO:0008150(biological_process);GO:0008150(biological_process)","NA","NA","NA","LIM domain containing preferred translocation partner in lipoma [Source:HGNC Symbol;Acc:HGNC:6679]",{"v":0.272087711768161,"d":"0.27"},{"v":0.760119819815939,"d":"0.76"},{"v":0.357953712921269,"d":"0.36"},{"v":-1.48215505057187,"d":"-1.48"},{"v":0.0296771225664101,"d":"0.03"},{"v":0.53740136833791,"d":"0.54"},"down","yes"]
["ENSG00000085365","SCAMP1","ENST00000621999;ENST00000510030;ENST00000320280;ENST00000511551;ENST00000614488","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0015031(protein transport);GO:0005794(Golgi apparatus);GO:0005515(protein binding);GO:0005886(plasma membrane);GO:0005768(endosome);GO:0005802(trans-Golgi network);GO:0055038(recycling endosome membrane);GO:0043312(neutrophil degranulation);GO:0035579(specific granule membrane);GO:0006892(post-Golgi vesicle-mediated transport);GO:0006887(exocytosis);GO:0030136(clathrin-coated vesicle);GO:0030672(synaptic vesicle membrane);GO:0042589(zymogen granule membrane);GO:0045202(synapse);GO:0045202(synapse)","NA","NA","NA","secretory carrier membrane protein 1 [Source:HGNC Symbol;Acc:HGNC:10563]",{"v":2.12219626145711,"d":"2.12"},{"v":0.783637353309832,"d":"0.78"},{"v":2.70813566057518,"d":"2.71"},{"v":1.4373000106769,"d":"1.44"},{"v":0.0300184969809265,"d":"0.03"},{"v":0.542666754331097,"d":"0.54"},"up","yes"]
["MSTRG.14201","ZDHHC2","ENST00000262096;ENST00000517334","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016740(transferase activity);GO:0005794(Golgi apparatus);GO:0016746(transferase activity, transferring acyl groups);GO:0019706(protein-cysteine S-palmitoyltransferase activity);GO:0005783(endoplasmic reticulum);GO:0005886(plasma membrane);GO:0016409(palmitoyltransferase activity);GO:0018345(protein palmitoylation);GO:0005887(integral component of plasma membrane);GO:0055038(recycling endosome membrane);GO:0044267(cellular protein metabolic process);GO:0044267(cellular protein metabolic process)","NA","NA","NA","zinc finger DHHC-type containing 2 [Source:HGNC Symbol;Acc:HGNC:18469]",{"v":1.00600938708241,"d":"1.01"},{"v":2.81222958990349,"d":"2.81"},{"v":0.357726620434619,"d":"0.36"},{"v":-1.48307061356847,"d":"-1.48"},{"v":0.0300580240108655,"d":"0.03"},{"v":0.542666754331097,"d":"0.54"},"down","yes"]
["MSTRG.3397","SP1","ENST00000426431;ENST00000327443;ENST00000551969;ENST00000548560","GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0005654(nucleoplasm);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0042803(protein homodimerization activity);GO:0005515(protein binding);GO:0048511(rhythmic process);GO:0045893(positive regulation of transcription, DNA-templated);GO:0016032(viral process);GO:0008022(protein C-terminus binding);GO:0008134(transcription factor binding);GO:0043425(bHLH transcription factor binding);GO:0000790(nuclear chromatin);GO:0000982(transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0042795(snRNA transcription from RNA polymerase II promoter);GO:0044212(transcription regulatory region DNA binding);GO:0001046(core promoter sequence-specific DNA binding);GO:0045540(regulation of cholesterol biosynthetic process);GO:0000977(RNA polymerase II regulatory region sequence-specific DNA binding);GO:0001103(RNA polymerase II repressing transcription factor binding);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:0042826(histone deacetylase binding);GO:0043923(positive regulation by host of viral transcription);GO:0001077(transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0003690(double-stranded DNA binding);GO:0035035(histone acetyltransferase binding);GO:0043565(sequence-specific DNA binding);GO:0070491(repressing transcription factor binding);GO:0071837(HMG box domain binding);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0032869(cellular response to insulin stimulus);GO:0100057(regulation of phenotypic switching by transcription from RNA polymerase II promoter);GO:1904828(positive regulation of hydrogen sulfide biosynthetic process);GO:0017053(transcriptional repressor complex);GO:0032993(protein-DNA complex);GO:0032993(protein-DNA complex)","04350(TGF-beta signaling pathway);04137(Mitophagy - animal);04915(Estrogen signaling pathway);04927(Cortisol synthesis and secretion);05200(Pathways in cancer);05231(Choline metabolism in cancer);05202(Transcriptional misregulation in cancers);05224(Breast cancer);05016(Huntington's disease);01522(Endocrine resistance);01522(Endocrine resistance)","K04684","NA","Sp1 transcription factor [Source:HGNC Symbol;Acc:HGNC:11205]",{"v":5.12993483892119,"d":"5.13"},{"v":14.2388670703947,"d":"14.24"},{"v":0.360276896578893,"d":"0.36"},{"v":-1.47282195563931,"d":"-1.47"},{"v":0.0301934005479193,"d":"0.03"},{"v":0.54372346452437,"d":"0.54"},"down","yes"]
["MSTRG.13400","IGF2R","ENST00000356956;ENST00000475834;ENST00000464636;ENST00000487607;ENST00000475584","GO:0006810(transport);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005794(Golgi apparatus);GO:0005215(transporter activity);GO:0005765(lysosomal membrane);GO:0005515(protein binding);GO:0005925(focal adhesion);GO:0005764(lysosome);GO:0005886(plasma membrane);GO:0042802(identical protein binding);GO:0070062(extracellular exosome);GO:0061024(membrane organization);GO:0005802(trans-Golgi network);GO:0005769(early endosome);GO:0005887(integral component of plasma membrane);GO:0043312(neutrophil degranulation);GO:0007165(signal transduction);GO:0032588(trans-Golgi network membrane);GO:0004872(receptor activity);GO:0009986(cell surface);GO:0030667(secretory granule membrane);GO:0030133(transport vesicle);GO:0051219(phosphoprotein binding);GO:0030139(endocytic vesicle);GO:0030665(clathrin-coated vesicle membrane);GO:0006898(receptor-mediated endocytosis);GO:0005768(endosome);GO:0005010(insulin-like growth factor-activated receptor activity);GO:0030140(trans-Golgi network transport vesicle);GO:0005770(late endosome);GO:0001965(G-protein alpha-subunit binding);GO:0001972(retinoic acid binding);GO:0004930(G-protein coupled receptor activity);GO:0005520(insulin-like growth factor binding);GO:0005537(mannose binding);GO:0019899(enzyme binding);GO:0031995(insulin-like growth factor II binding);GO:0001889(liver development);GO:0007186(G-protein coupled receptor signaling pathway);GO:0007283(spermatogenesis);GO:0009791(post-embryonic development);GO:0031100(animal organ regeneration);GO:0032526(response to retinoic acid);GO:0042981(regulation of apoptotic process);GO:0043065(positive regulation of apoptotic process);GO:0048009(insulin-like growth factor receptor signaling pathway);GO:0005615(extracellular space);GO:0005634(nucleus);GO:0005641(nuclear envelope lumen);GO:0030118(clathrin coat);GO:0048471(perinuclear region of cytoplasm);GO:0048471(perinuclear region of cytoplasm)","04144(Endocytosis);04142(Lysosome);04142(Lysosome)","K06564","NA","insulin like growth factor 2 receptor [Source:HGNC Symbol;Acc:HGNC:5467]",{"v":18.4575018920931,"d":"18.46"},{"v":51.1557273471263,"d":"51.16"},{"v":0.360810076393723,"d":"0.36"},{"v":-1.47068846538425,"d":"-1.47"},{"v":0.0302277445917892,"d":"0.03"},{"v":0.54372346452437,"d":"0.54"},"down","yes"]
["MSTRG.6861","TMEM101","ENST00000206380;ENST00000587529;ENST00000585950;ENST00000589334;ENST00000591162","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0004871(signal transducer activity);GO:0007165(signal transduction);GO:0005575(cellular_component);GO:0043123(positive regulation of I-kappaB kinase/NF-kappaB signaling);GO:0043123(positive regulation of I-kappaB kinase/NF-kappaB signaling)","NA","NA","NA","transmembrane protein 101 [Source:HGNC Symbol;Acc:HGNC:28653]",{"v":1.29945220270716,"d":"1.30"},{"v":3.65695064014526,"d":"3.66"},{"v":0.355337637987792,"d":"0.36"},{"v":-1.49273758532757,"d":"-1.49"},{"v":0.030269859922879,"d":"0.03"},{"v":0.54372346452437,"d":"0.54"},"down","yes"]
["ENSG00000213742","ZNF337-AS1","ENST00000414393;ENST00000439498;ENST00000428254;ENST00000455791","NA","NA","NA","NA","ZNF337 antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:40759]",{"v":0.642256360211002,"d":"0.64"},{"v":0.230214299736247,"d":"0.23"},{"v":2.78981957657203,"d":"2.79"},{"v":1.4801718229858,"d":"1.48"},{"v":0.0302971636518728,"d":"0.03"},{"v":0.54372346452437,"d":"0.54"},"up","yes"]
["MSTRG.12600","RNF130","ENST00000521389;ENST00000519708;MSTRG.12600.2;ENST00000522208;ENST00000520911;ENST00000521901;ENST00000261947;ENST00000523487;ENST00000520564","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0016740(transferase activity);GO:0016567(protein ubiquitination);GO:0006915(apoptotic process);GO:0004842(ubiquitin-protein transferase activity);GO:0012501(programmed cell death);GO:0012501(programmed cell death)","NA","NA","NA","ring finger protein 130 [Source:HGNC Symbol;Acc:HGNC:18280]",{"v":5.40219162835427,"d":"5.40"},{"v":14.9738974008841,"d":"14.97"},{"v":0.360773917686608,"d":"0.36"},{"v":-1.47083305281388,"d":"-1.47"},{"v":0.0303614369899965,"d":"0.03"},{"v":0.544066107490383,"d":"0.54"},"down","yes"]
["MSTRG.14627","HGH1","ENST00000347708;ENST00000530409;ENST00000530074;ENST00000525101;ENST00000534255","GO:0003674(molecular_function);GO:0008150(biological_process);GO:0005575(cellular_component);GO:0005575(cellular_component)","NA","NA","NA","HGH1 homolog [Source:HGNC Symbol;Acc:HGNC:24161]",{"v":3.48895183937456,"d":"3.49"},{"v":1.28719826190476,"d":"1.29"},{"v":2.71050073841127,"d":"2.71"},{"v":1.43855939995157,"d":"1.44"},{"v":0.0304549972867031,"d":"0.03"},{"v":0.544931764229537,"d":"0.54"},"up","yes"]
["ENSG00000091106","NLRC4","ENST00000360906;ENST00000402280","GO:0005737(cytoplasm);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0042981(regulation of apoptotic process);GO:0016567(protein ubiquitination);GO:0005829(cytosol);GO:0005515(protein binding);GO:0006915(apoptotic process);GO:0002376(immune system process);GO:0045087(innate immune response);GO:0006954(inflammatory response);GO:0005634(nucleus);GO:0042802(identical protein binding);GO:0004842(ubiquitin-protein transferase activity);GO:0043065(positive regulation of apoptotic process);GO:0051092(positive regulation of NF-kappaB transcription factor activity);GO:0002218(activation of innate immune response);GO:0070269(pyroptosis);GO:0009966(regulation of signal transduction);GO:1990001(inhibition of cysteine-type endopeptidase activity involved in apoptotic process);GO:0051260(protein homooligomerization);GO:0042803(protein homodimerization activity);GO:0000287(magnesium ion binding);GO:0072557(IPAF inflammasome complex);GO:0006919(activation of cysteine-type endopeptidase activity involved in apoptotic process);GO:0043027(cysteine-type endopeptidase inhibitor activity involved in apoptotic process);GO:0005622(intracellular);GO:0016045(detection of bacterium);GO:0042742(defense response to bacterium);GO:0050702(interleukin-1 beta secretion);GO:0043281(regulation of cysteine-type endopeptidase activity involved in apoptotic process);GO:0043281(regulation of cysteine-type endopeptidase activity involved in apoptotic process)","04621(NOD-like receptor signaling pathway);05132(Salmonella infection);05134(Legionellosis);05134(Legionellosis)","K12805","NA","NLR family CARD domain containing 4 [Source:HGNC Symbol;Acc:HGNC:16412]",{"v":1.69232273813466,"d":"1.69"},{"v":4.71903875827815,"d":"4.72"},{"v":0.358615986182776,"d":"0.36"},{"v":-1.47948829359531,"d":"-1.48"},{"v":0.030615716432522,"d":"0.03"},{"v":0.54699474373951,"d":"0.55"},"down","yes"]
["MSTRG.10089","SLC19A1","ENST00000311124;ENST00000417954;ENST00000380010;ENST00000567670;ENST00000486303;ENST00000460174;ENST00000427839;ENST00000468508;ENST00000485649;ENST00000443742;ENST00000528477","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0006810(transport);GO:0005887(integral component of plasma membrane);GO:0008517(folic acid transporter activity);GO:0015884(folic acid transport);GO:0015350(methotrexate transporter activity);GO:0051958(methotrexate transport);GO:0005886(plasma membrane);GO:0016324(apical plasma membrane);GO:0046655(folic acid metabolic process);GO:0005542(folic acid binding);GO:0016323(basolateral plasma membrane);GO:0008518(reduced folate carrier activity);GO:0098838(reduced folate transmembrane transport);GO:0098838(reduced folate transmembrane transport)","04977(Vitamin digestion and absorption);01523(Antifolate resistance);01523(Antifolate resistance)","K14609","NA","solute carrier family 19 member 1 [Source:HGNC Symbol;Acc:HGNC:10937]",{"v":2.08540572326775,"d":"2.09"},{"v":5.78501267953379,"d":"5.79"},{"v":0.360484209593091,"d":"0.36"},{"v":-1.47199202887666,"d":"-1.47"},{"v":0.0307341442880126,"d":"0.03"},{"v":0.547986625263952,"d":"0.55"},"down","yes"]
["MSTRG.6169","CMIP","MSTRG.6169.1","NA","NA","NA","NA",null,{"v":1.562894,"d":"1.56"},{"v":4.50035,"d":"4.50"},{"v":0.347282766895908,"d":"0.35"},{"v":-1.52581727279582,"d":"-1.53"},{"v":0.0307622453644271,"d":"0.03"},{"v":0.547986625263952,"d":"0.55"},"down","yes"]
["MSTRG.12405","ARAP3","ENST00000512390;MSTRG.12405.4;ENST00000239440;ENST00000524066;ENST00000504448;ENST00000508305","GO:0007165(signal transduction);GO:0043547(positive regulation of GTPase activity);GO:0005096(GTPase activator activity);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0046872(metal ion binding);GO:0005886(plasma membrane);GO:0005856(cytoskeleton);GO:0042995(cell projection);GO:0005515(protein binding);GO:0016192(vesicle-mediated transport);GO:0005829(cytosol);GO:0030027(lamellipodium);GO:0051056(regulation of small GTPase mediated signal transduction);GO:0007010(cytoskeleton organization);GO:0005547(phosphatidylinositol-3,4,5-trisphosphate binding);GO:0043325(phosphatidylinositol-3,4-bisphosphate binding);GO:0008360(regulation of cell shape);GO:0001726(ruffle);GO:0030336(negative regulation of cell migration);GO:0035024(negative regulation of Rho protein signal transduction);GO:0035021(negative regulation of Rac protein signal transduction);GO:0035021(negative regulation of Rac protein signal transduction)","04015(Rap1 signaling pathway);04024(cAMP signaling pathway);04144(Endocytosis);04144(Endocytosis)","K12490","NA","ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3 [Source:HGNC Symbol;Acc:HGNC:24097]",{"v":4.14536768093323,"d":"4.15"},{"v":11.4722038595334,"d":"11.47"},{"v":0.361340134091884,"d":"0.36"},{"v":-1.46857059090676,"d":"-1.47"},{"v":0.0308444642862007,"d":"0.03"},{"v":0.54863964392087,"d":"0.55"},"down","yes"]
["MSTRG.9411","CXCR2","ENST00000318507;ENST00000454148;ENST00000418878;ENST00000428565;ENST00000415392;ENST00000453237;ENST00000449014","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0004930(G-protein coupled receptor activity);GO:0007186(G-protein coupled receptor signaling pathway);GO:0004871(signal transducer activity);GO:0007165(signal transduction);GO:0006935(chemotaxis);GO:0070098(chemokine-mediated signaling pathway);GO:0016494(C-X-C chemokine receptor activity);GO:0019959(interleukin-8 binding);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0005887(integral component of plasma membrane);GO:0030593(neutrophil chemotaxis);GO:0005622(intracellular);GO:0043312(neutrophil degranulation);GO:0008284(positive regulation of cell proliferation);GO:0006954(inflammatory response);GO:0009986(cell surface);GO:0030667(secretory granule membrane);GO:0002407(dendritic cell chemotaxis);GO:0006968(cellular defense response);GO:0031623(receptor internalization);GO:0007166(cell surface receptor signaling pathway);GO:0007200(phospholipase C-activating G-protein coupled receptor signaling pathway);GO:0042629(mast cell granule);GO:0042119(neutrophil activation);GO:0004918(interleukin-8 receptor activity);GO:0038112(interleukin-8-mediated signaling pathway);GO:0038112(interleukin-8-mediated signaling pathway)","04072(Phospholipase D signaling pathway);04060(Cytokine-cytokine receptor interaction);04144(Endocytosis);04062(Chemokine signaling pathway);05120(Epithelial cell signaling in Helicobacter pylori infection);05120(Epithelial cell signaling in Helicobacter pylori infection)","K05050","NA","C-X-C motif chemokine receptor 2 [Source:HGNC Symbol;Acc:HGNC:6027]",{"v":114.018629610028,"d":"114.02"},{"v":314.445522793872,"d":"314.45"},{"v":0.36260217222037,"d":"0.36"},{"v":-1.46354052710764,"d":"-1.46"},{"v":0.0310138362774751,"d":"0.03"},{"v":0.550838667335332,"d":"0.55"},"down","yes"]
["ENSG00000249709","ZNF564","ENST00000339282;ENST00000427105;ENST00000465410;ENST00000596193","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0005622(intracellular);GO:0005515(protein binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0044212(transcription regulatory region DNA binding);GO:0044212(transcription regulatory region DNA binding)","NA","NA","NA","zinc finger protein 564 [Source:HGNC Symbol;Acc:HGNC:31106]",{"v":2.63107840005522,"d":"2.63"},{"v":0.97427266813915,"d":"0.97"},{"v":2.70055651369195,"d":"2.70"},{"v":1.43325673942859,"d":"1.43"},{"v":0.0311126863760591,"d":"0.03"},{"v":0.551073197389528,"d":"0.55"},"up","yes"]
["ENSG00000114999","TTL","ENST00000233336;ENST00000485537;ENST00000460450;ENST00000476615","GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0006464(cellular protein modification process);GO:0016874(ligase activity);GO:0004835(tubulin-tyrosine ligase activity);GO:0000226(microtubule cytoskeleton organization);GO:0030516(regulation of axon extension);GO:0030516(regulation of axon extension)","NA","NA","NA","tubulin tyrosine ligase [Source:HGNC Symbol;Acc:HGNC:21586]",{"v":0.202667275235189,"d":"0.20"},{"v":0.569617072400203,"d":"0.57"},{"v":0.355795647734376,"d":"0.36"},{"v":-1.49087923192264,"d":"-1.49"},{"v":0.0312164155172614,"d":"0.03"},{"v":0.551073197389528,"d":"0.55"},"down","yes"]
["ENSG00000280433","FP565260.7","ENST00000623998;ENST00000623744","GO:0005829(cytosol);GO:0006891(intra-Golgi vesicle-mediated transport);GO:0034498(early endosome to Golgi transport);GO:1990071(TRAPPII protein complex);GO:1990071(TRAPPII protein complex)","NA","NA","NA",null,{"v":3.54748548771022,"d":"3.55"},{"v":1.32615364184069,"d":"1.33"},{"v":2.67501847130348,"d":"2.68"},{"v":1.41954885351974,"d":"1.42"},{"v":0.0312480219349717,"d":"0.03"},{"v":0.551073197389528,"d":"0.55"},"up","yes"]
["MSTRG.8657","COX7A2L","ENST00000234301;ENST00000463055;ENST00000482463;ENST00000378669;ENST00000464443;ENST00000468711","GO:0005730(nucleolus);GO:0005739(mitochondrion);GO:1902600(hydrogen ion transmembrane transport);GO:0004129(cytochrome-c oxidase activity);GO:0009055(electron carrier activity);GO:0005746(mitochondrial respiratory chain);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005743(mitochondrial inner membrane);GO:0006123(mitochondrial electron transport, cytochrome c to oxygen);GO:0006123(mitochondrial electron transport, cytochrome c to oxygen)","00190(Oxidative phosphorylation);04260(Cardiac muscle contraction);05010(Alzheimer's disease);05012(Parkinson's disease);05016(Huntington's disease);04932(Non-alcoholic fatty liver disease (NAFLD));04932(Non-alcoholic fatty liver disease (NAFLD))","K02270","NA","cytochrome c oxidase subunit 7A2 like [Source:HGNC Symbol;Acc:HGNC:2289]",{"v":3.95903410205174,"d":"3.96"},{"v":10.9372504322926,"d":"10.94"},{"v":0.361977091642938,"d":"0.36"},{"v":-1.46602969818361,"d":"-1.47"},{"v":0.0312514080581657,"d":"0.03"},{"v":0.551073197389528,"d":"0.55"},"down","yes"]
["MSTRG.12213","ERAP2","ENST00000437043;ENST00000379904;ENST00000510373;ENST00000512869;ENST00000507346;ENST00000513084;ENST00000513368;ENST00000515387","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0016787(hydrolase activity);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0008233(peptidase activity);GO:0006508(proteolysis);GO:0008237(metallopeptidase activity);GO:0002376(immune system process);GO:0004177(aminopeptidase activity);GO:0019885(antigen processing and presentation of endogenous peptide antigen via MHC class I);GO:0002250(adaptive immune response);GO:0070006(metalloaminopeptidase activity);GO:0005886(plasma membrane);GO:0007165(signal transduction);GO:0007267(cell-cell signaling);GO:0005788(endoplasmic reticulum lumen);GO:0002474(antigen processing and presentation of peptide antigen via MHC class I);GO:0042277(peptide binding);GO:0004175(endopeptidase activity);GO:0043171(peptide catabolic process);GO:0008217(regulation of blood pressure);GO:0008217(regulation of blood pressure)","NA","NA","NA","endoplasmic reticulum aminopeptidase 2 [Source:HGNC Symbol;Acc:HGNC:29499]",{"v":8.03854197359202,"d":"8.04"},{"v":3.02001063419563,"d":"3.02"},{"v":2.66175949268902,"d":"2.66"},{"v":1.41238022024294,"d":"1.41"},{"v":0.0312684721559511,"d":"0.03"},{"v":0.551073197389528,"d":"0.55"},"up","yes"]
["MSTRG.11182","TMCC1","MSTRG.11182.5;ENST00000515024;MSTRG.11182.12;MSTRG.11182.14;ENST00000510521;ENST00000505616;MSTRG.11182.1;ENST00000508729;ENST00000426664;MSTRG.11182.15;ENST00000508869;ENST00000393238;ENST00000510323;ENST00000512902;ENST00000509440;ENST00000505924;ENST00000432054","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005829(cytosol);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0042803(protein homodimerization activity);GO:0005515(protein binding);GO:0051291(protein heterooligomerization);GO:0046982(protein heterodimerization activity);GO:0007029(endoplasmic reticulum organization);GO:0051260(protein homooligomerization);GO:0005791(rough endoplasmic reticulum);GO:0005791(rough endoplasmic reticulum)","NA","NA","NA","transmembrane and coiled-coil domain family 1 [Source:HGNC Symbol;Acc:HGNC:29116]",{"v":2.99788956892039,"d":"3.00"},{"v":8.2812679087241,"d":"8.28"},{"v":0.362008523569464,"d":"0.36"},{"v":-1.4659044286103,"d":"-1.47"},{"v":0.0313087675028945,"d":"0.03"},{"v":0.551073197389528,"d":"0.55"},"down","yes"]
["ENSG00000130764","LRRC47","ENST00000378251;ENST00000479239;ENST00000462356","GO:0003723(RNA binding);GO:0005515(protein binding);GO:0004826(phenylalanine-tRNA ligase activity);GO:0004826(phenylalanine-tRNA ligase activity)","NA","NA","NA","leucine rich repeat containing 47 [Source:HGNC Symbol;Acc:HGNC:29207]",{"v":3.76486144397697,"d":"3.76"},{"v":1.40549659499557,"d":"1.41"},{"v":2.67866991452145,"d":"2.68"},{"v":1.42151681260135,"d":"1.42"},{"v":0.0313473791904855,"d":"0.03"},{"v":0.551073197389528,"d":"0.55"},"up","yes"]
["MSTRG.2339","HSD17B12;AC068205.2","ENST00000278353;ENST00000533090;ENST00000636894;ENST00000532864;ENST00000533802;ENST00000395700;ENST00000532178;ENST00000525736;ENST00000529261;ENST00000636722;ENST00000534053","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0006629(lipid metabolic process);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0006633(fatty acid biosynthetic process);GO:0006694(steroid biosynthetic process);GO:0005515(protein binding);GO:0035338(long-chain fatty-acyl-CoA biosynthetic process);GO:0004303(estradiol 17-beta-dehydrogenase activity);GO:0006703(estrogen biosynthetic process);GO:0001968(fibronectin binding);GO:0005518(collagen binding);GO:0008201(heparin binding);GO:0016509(long-chain-3-hydroxyacyl-CoA dehydrogenase activity);GO:0102339(3-oxo-arachidoyl-CoA reductase activity);GO:0102340(3-oxo-behenoyl-CoA reductase activity);GO:0102341(3-oxo-lignoceroyl-CoA reductase activity);GO:0102342(3-oxo-cerotoyl-CoA reductase activity);GO:0010811(positive regulation of cell-substrate adhesion);GO:0030198(extracellular matrix organization);GO:0005578(proteinaceous extracellular matrix);GO:0005578(proteinaceous extracellular matrix)","00062(Fatty acid elongation);00140(Steroid hormone biosynthesis);01040(Biosynthesis of unsaturated fatty acids);01040(Biosynthesis of unsaturated fatty acids)","K10251","EC:1.1.1.62;EC:1.1.1.330","hydroxysteroid 17-beta dehydrogenase 12 [Source:HGNC Symbol;Acc:HGNC:18646]",{"v":0.307008491621598,"d":"0.31"},{"v":0.867353127404912,"d":"0.87"},{"v":0.353960205966117,"d":"0.35"},{"v":-1.49834092068762,"d":"-1.50"},{"v":0.0314816338874867,"d":"0.03"},{"v":0.55262658203078,"d":"0.55"},"down","yes"]
["MSTRG.14361","LYN","ENST00000520220;ENST00000519728;ENST00000420292;ENST00000520050","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005794(Golgi apparatus);GO:0043231(intracellular membrane-bounded organelle);GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0004713(protein tyrosine kinase activity);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0006974(cellular response to DNA damage stimulus);GO:0004715(non-membrane spanning protein tyrosine kinase activity);GO:0030218(erythrocyte differentiation);GO:0023014(signal transduction by protein phosphorylation);GO:0048471(perinuclear region of cytoplasm);GO:0045121(membrane raft);GO:0002376(immune system process);GO:0045087(innate immune response);GO:0006954(inflammatory response);GO:0002250(adaptive immune response);GO:0038095(Fc-epsilon receptor signaling pathway);GO:0038096(Fc-gamma receptor signaling pathway involved in phagocytosis);GO:0050900(leukocyte migration);GO:0042629(mast cell granule);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0008285(negative regulation of cell proliferation);GO:0002223(stimulatory C-type lectin receptor signaling pathway);GO:0034136(negative regulation of toll-like receptor 2 signaling pathway);GO:0034144(negative regulation of toll-like receptor 4 signaling pathway);GO:0016032(viral process);GO:0008284(positive regulation of cell proliferation);GO:0044325(ion channel binding);GO:0007165(signal transduction);GO:2000670(positive regulation of dendritic cell apoptotic process);GO:0030168(platelet activation);GO:0001933(negative regulation of protein phosphorylation);GO:0048013(ephrin receptor signaling pathway);GO:0046777(protein autophosphorylation);GO:0007169(transmembrane receptor protein tyrosine kinase signaling pathway);GO:0007417(central nervous system development);GO:0033628(regulation of cell adhesion mediated by integrin);GO:0070373(negative regulation of ERK1 and ERK2 cascade);GO:0030889(negative regulation of B cell proliferation);GO:0005102(receptor binding);GO:0001932(regulation of protein phosphorylation);GO:0033003(regulation of mast cell activation);GO:0007596(blood coagulation);GO:0031295(T cell costimulation);GO:0043407(negative regulation of MAP kinase activity);GO:0051272(positive regulation of cellular component movement);GO:0038083(peptidyl-tyrosine autophosphorylation);GO:0042531(positive regulation of tyrosine phosphorylation of STAT protein);GO:0060397(JAK-STAT cascade involved in growth hormone signaling pathway);GO:0031234(extrinsic component of cytoplasmic side of plasma membrane);GO:0097028(dendritic cell differentiation);GO:0070372(regulation of ERK1 and ERK2 cascade);GO:0046875(ephrin receptor binding);GO:0018108(peptidyl-tyrosine phosphorylation);GO:0031663(lipopolysaccharide-mediated signaling pathway);GO:0050777(negative regulation of immune response);GO:0001817(regulation of cytokine production);GO:0009725(response to hormone);GO:0004716(signal transducer, downstream of receptor, with protein tyrosine kinase activity);GO:0001934(positive regulation of protein phosphorylation);GO:0043304(regulation of mast cell degranulation);GO:0005161(platelet-derived growth factor receptor binding);GO:0005178(integrin binding);GO:0017124(SH3 domain binding);GO:0019899(enzyme binding);GO:0031625(ubiquitin protein ligase binding);GO:0032403(protein complex binding);GO:0043015(gamma-tubulin binding);GO:0043208(glycosphingolipid binding);GO:0051219(phosphoprotein binding);GO:0001782(B cell homeostasis);GO:0002431(Fc receptor mediated stimulatory signaling pathway);GO:0002513(tolerance induction to self antigen);GO:0002553(histamine secretion by mast cell);GO:0002576(platelet degranulation);GO:0002762(negative regulation of myeloid leukocyte differentiation);GO:0002768(immune response-regulating cell surface receptor signaling pathway);GO:0002774(Fc receptor mediated inhibitory signaling pathway);GO:0002902(regulation of B cell apoptotic process);GO:0006991(response to sterol depletion);GO:0009636(response to toxic substance);GO:0009743(response to carbohydrate);GO:0010976(positive regulation of neuron projection development);GO:0014003(oligodendrocyte development);GO:0014070(response to organic cyclic compound);GO:0030097(hemopoiesis);GO:0030335(positive regulation of cell migration);GO:0031175(neuron projection development);GO:0031668(cellular response to extracellular stimulus);GO:0032868(response to insulin);GO:0034605(cellular response to heat);GO:0035556(intracellular signal transduction);GO:0042327(positive regulation of phosphorylation);GO:0042493(response to drug);GO:0043200(response to amino acid);GO:0043434(response to peptide hormone);GO:0043552(positive regulation of phosphatidylinositol 3-kinase activity);GO:0045646(regulation of erythrocyte differentiation);GO:0048678(response to axon injury);GO:0050663(cytokine secretion);GO:0050707(regulation of cytokine secretion);GO:0050727(regulation of inflammatory response);GO:0050731(positive regulation of peptidyl-tyrosine phosphorylation);GO:0050853(B cell receptor signaling pathway);GO:0050855(regulation of B cell receptor signaling pathway);GO:0050861(positive regulation of B cell receptor signaling pathway);GO:0051279(regulation of release of sequestered calcium ion into cytosol);GO:0060252(positive regulation of glial cell proliferation);GO:0060369(positive regulation of Fc receptor mediated stimulatory signaling pathway);GO:0070304(positive regulation of stress-activated protein kinase signaling cascade);GO:0070447(positive regulation of oligodendrocyte progenitor proliferation);GO:0070667(negative regulation of mast cell proliferation);GO:0070668(positive regulation of mast cell proliferation);GO:0071300(cellular response to retinoic acid);GO:0090025(regulation of monocyte chemotaxis);GO:0090330(regulation of platelet aggregation);GO:1902532(negative regulation of intracellular signal transduction);GO:1902961(positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process);GO:0005758(mitochondrial intermembrane space);GO:0005913(cell-cell adherens junction);GO:0014069(postsynaptic density);GO:0030061(mitochondrial crista);GO:0031966(mitochondrial membrane);GO:0034666(integrin alpha2-beta1 complex);GO:0034666(integrin alpha2-beta1 complex)","04064(NF-kappa B signaling pathway);04611(Platelet activation);04662(B cell receptor signaling pathway);04664(Fc epsilon RI signaling pathway);04666(Fc gamma R-mediated phagocytosis);04062(Chemokine signaling pathway);04730(Long-term depression);05203(Viral carcinogenesis);05120(Epithelial cell signaling in Helicobacter pylori infection);05167(Kaposi's sarcoma-associated herpesvirus infection);05169(Epstein-Barr virus infection);05169(Epstein-Barr virus infection)","K05854","EC:2.7.10.2","LYN proto-oncogene, Src family tyrosine kinase [Source:HGNC Symbol;Acc:HGNC:6735]",{"v":16.4537070835893,"d":"16.45"},{"v":45.2473622582053,"d":"45.25"},{"v":0.363639033579367,"d":"0.36"},{"v":-1.45942102591398,"d":"-1.46"},{"v":0.0315425941368586,"d":"0.03"},{"v":0.552890711202403,"d":"0.55"},"down","yes"]
["MSTRG.15301","KANTR","ENST00000603385;ENST00000366185;ENST00000604062;ENST00000604849","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0010629(negative regulation of gene expression);GO:0010629(negative regulation of gene expression)","NA","NA","NA","KDM5C adjacent transcript [Source:HGNC Symbol;Acc:HGNC:49510]",{"v":0.508915966656593,"d":"0.51"},{"v":0.186920277022263,"d":"0.19"},{"v":2.7226364884746,"d":"2.72"},{"v":1.44500437449211,"d":"1.45"},{"v":0.0316016680464995,"d":"0.03"},{"v":0.55312105612783,"d":"0.55"},"up","yes"]
["MSTRG.11135","CSTA","ENST00000264474;ENST00000479204","GO:0005737(cytoplasm);GO:0007155(cell adhesion);GO:0005622(intracellular);GO:0010951(negative regulation of endopeptidase activity);GO:0005615(extracellular space);GO:0004869(cysteine-type endopeptidase inhibitor activity);GO:0030414(peptidase inhibitor activity);GO:0010466(negative regulation of peptidase activity);GO:0004866(endopeptidase inhibitor activity);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0031012(extracellular matrix);GO:0030674(protein binding, bridging);GO:0030216(keratinocyte differentiation);GO:0005198(structural molecule activity);GO:0016337(single organismal cell-cell adhesion);GO:0070268(cornification);GO:0001533(cornified envelope);GO:0002020(protease binding);GO:0018149(peptide cross-linking);GO:0045861(negative regulation of proteolysis);GO:0045861(negative regulation of proteolysis)","NA","NA","NA","cystatin A [Source:HGNC Symbol;Acc:HGNC:2481]",{"v":11.7367613306628,"d":"11.74"},{"v":32.3163538237436,"d":"32.32"},{"v":0.363183340381659,"d":"0.36"},{"v":-1.46123006874533,"d":"-1.46"},{"v":0.0317813011110147,"d":"0.03"},{"v":0.555457805484526,"d":"0.56"},"down","yes"]
["ENSG00000181409","AATK","ENST00000326724;ENST00000576053;ENST00000575363;ENST00000374792;ENST00000572798;ENST00000417379","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0048471(perinuclear region of cytoplasm);GO:0048471(perinuclear region of cytoplasm)","NA","NA","NA","apoptosis associated tyrosine kinase [Source:HGNC Symbol;Acc:HGNC:21]",{"v":1.44626210522088,"d":"1.45"},{"v":3.98093558746988,"d":"3.98"},{"v":0.363297037453466,"d":"0.36"},{"v":-1.4607784937049,"d":"-1.46"},{"v":0.032031915346219,"d":"0.03"},{"v":0.559026557390101,"d":"0.56"},"down","yes"]
["ENSG00000214944","ARHGEF28","ENST00000503341;ENST00000545377;ENST00000512883;ENST00000296794;ENST00000510312","GO:0003723(RNA binding);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0046872(metal ion binding);GO:0035556(intracellular signal transduction);GO:0005886(plasma membrane);GO:0005089(Rho guanyl-nucleotide exchange factor activity);GO:0035023(regulation of Rho protein signal transduction);GO:0043547(positive regulation of GTPase activity);GO:0030154(cell differentiation);GO:0005085(guanyl-nucleotide exchange factor activity);GO:0005829(cytosol);GO:0048013(ephrin receptor signaling pathway);GO:0048013(ephrin receptor signaling pathway)","NA","NA","NA","Rho guanine nucleotide exchange factor 28 [Source:HGNC Symbol;Acc:HGNC:30322]",{"v":0.121151253889992,"d":"0.12"},{"v":0.0425631194211436,"d":"0.04"},{"v":2.84639038532991,"d":"2.85"},{"v":1.5091335425234,"d":"1.51"},{"v":0.0321063823290971,"d":"0.03"},{"v":0.559399458615651,"d":"0.56"},"up","yes"]
["ENSG00000230606","AC092683.1","ENST00000612970;ENST00000620023;ENST00000604397;ENST00000609751;ENST00000620272;ENST00000610408;ENST00000431244;ENST00000621982;ENST00000620051","NA","NA","NA","NA",null,{"v":0.706183952633573,"d":"0.71"},{"v":0.256410218264494,"d":"0.26"},{"v":2.75411782499684,"d":"2.75"},{"v":1.46159028129658,"d":"1.46"},{"v":0.0321573003133709,"d":"0.03"},{"v":0.559399458615651,"d":"0.56"},"up","yes"]
["ENSG00000175182","FAM131A","ENST00000450976;ENST00000340957;ENST00000418281;ENST00000418768;ENST00000310585;ENST00000497070;ENST00000487702;ENST00000433578;ENST00000639617","GO:0005576(extracellular region);GO:0005576(extracellular region)","NA","NA","NA","family with sequence similarity 131 member A [Source:HGNC Symbol;Acc:HGNC:28308]",{"v":0.152021541736695,"d":"0.15"},{"v":0.437464875854342,"d":"0.44"},{"v":0.347505708749317,"d":"0.35"},{"v":-1.52489141657157,"d":"-1.52"},{"v":0.032192644479376,"d":"0.03"},{"v":0.559399458615651,"d":"0.56"},"down","yes"]
["MSTRG.8392","ZNF611","ENST00000597566;ENST00000601249;ENST00000640952;ENST00000602046;ENST00000595001;ENST00000597343;ENST00000596776;ENST00000543227;ENST00000540744;ENST00000599798;ENST00000319783;ENST00000598723;ENST00000598639;ENST00000601447;ENST00000602162","GO:0003676(nucleic acid binding);GO:0006355(regulation of transcription, DNA-templated);GO:0005622(intracellular);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding)","NA","NA","NA","zinc finger protein 611 [Source:HGNC Symbol;Acc:HGNC:28766]",{"v":0.129510474258534,"d":"0.13"},{"v":0.377896175713486,"d":"0.38"},{"v":0.342714434762437,"d":"0.34"},{"v":-1.54492113699113,"d":"-1.54"},{"v":0.0323263428330308,"d":"0.03"},{"v":0.560441707139952,"d":"0.56"},"down","yes"]
["ENSG00000122188","LAX1","ENST00000442561;ENST00000367215;ENST00000367217","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005794(Golgi apparatus);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0006955(immune response);GO:0002376(immune system process);GO:0002250(adaptive immune response);GO:0035556(intracellular signal transduction);GO:0019901(protein kinase binding);GO:0042169(SH2 domain binding);GO:0000188(inactivation of MAPK activity);GO:0042113(B cell activation);GO:0046649(lymphocyte activation);GO:0048305(immunoglobulin secretion);GO:0050851(antigen receptor-mediated signaling pathway);GO:0050868(negative regulation of T cell activation);GO:0051249(regulation of lymphocyte activation);GO:0051249(regulation of lymphocyte activation)","NA","NA","NA","lymphocyte transmembrane adaptor 1 [Source:HGNC Symbol;Acc:HGNC:26005]",{"v":1.35083476766729,"d":"1.35"},{"v":0.496279614446529,"d":"0.50"},{"v":2.72192273940931,"d":"2.72"},{"v":1.44462611715309,"d":"1.44"},{"v":0.0323457055690306,"d":"0.03"},{"v":0.560441707139952,"d":"0.56"},"up","yes"]
["ENSG00000102230","PCYT1B","ENST00000379145;ENST00000496020;ENST00000379144","GO:0016740(transferase activity);GO:0003824(catalytic activity);GO:0006629(lipid metabolic process);GO:0009058(biosynthetic process);GO:0005783(endoplasmic reticulum);GO:0008654(phospholipid biosynthetic process);GO:0016779(nucleotidyltransferase activity);GO:0005789(endoplasmic reticulum membrane);GO:0006656(phosphatidylcholine biosynthetic process);GO:0005737(cytoplasm);GO:0006657(CDP-choline pathway);GO:0004105(choline-phosphate cytidylyltransferase activity);GO:0001541(ovarian follicle development);GO:0007283(spermatogenesis);GO:0007283(spermatogenesis)","00564(Glycerophospholipid metabolism);00440(Phosphonate and phosphinate metabolism);05231(Choline metabolism in cancer);05231(Choline metabolism in cancer)","K00968","EC:2.7.7.15","phosphate cytidylyltransferase 1, choline, beta [Source:HGNC Symbol;Acc:HGNC:8755]",{"v":0.690695196579658,"d":"0.69"},{"v":0.252868353375338,"d":"0.25"},{"v":2.73144182480773,"d":"2.73"},{"v":1.44966269634538,"d":"1.45"},{"v":0.0327112574661287,"d":"0.03"},{"v":0.564729921186269,"d":"0.56"},"up","yes"]
["MSTRG.11560","AC104078.2","MSTRG.11560.1","NA","NA","NA","NA",null,{"v":5.814555,"d":"5.81"},{"v":2.170578,"d":"2.17"},{"v":2.67880490818575,"d":"2.68"},{"v":1.42158951651374,"d":"1.42"},{"v":0.0327218809594397,"d":"0.03"},{"v":0.564729921186269,"d":"0.56"},"up","yes"]
["MSTRG.3831","VPS37B;AC027290.2","ENST00000267202;ENST00000623210;ENST00000535765;ENST00000371248;ENST00000543590","GO:0006810(transport);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0015031(protein transport);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0030496(midbody);GO:0005768(endosome);GO:0031902(late endosome membrane);GO:0070062(extracellular exosome);GO:0048306(calcium-dependent protein binding);GO:0016197(endosomal transport);GO:0016236(macroautophagy);GO:0019058(viral life cycle);GO:0036258(multivesicular body assembly);GO:0039702(viral budding via host ESCRT complex);GO:0075733(intracellular transport of virus);GO:0000813(ESCRT I complex);GO:0010008(endosome membrane);GO:0043657(host cell);GO:1902188(positive regulation of viral release from host cell);GO:1903774(positive regulation of viral budding via host ESCRT complex);GO:1903774(positive regulation of viral budding via host ESCRT complex)","04144(Endocytosis);04144(Endocytosis)","K12185","NA","VPS37B, ESCRT-I subunit [Source:HGNC Symbol;Acc:HGNC:25754]",{"v":0.862782285446705,"d":"0.86"},{"v":2.3611132519493,"d":"2.36"},{"v":0.365413342513073,"d":"0.37"},{"v":-1.45239878214251,"d":"-1.45"},{"v":0.0327513669893715,"d":"0.03"},{"v":0.564729921186269,"d":"0.56"},"down","yes"]
["MSTRG.2448","BEST1","ENST00000449131;ENST00000524877;ENST00000378043;ENST00000534553;ENST00000524926;ENST00000526988;ENST00000533521","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0007601(visual perception);GO:0006811(ion transport);GO:0005886(plasma membrane);GO:0005254(chloride channel activity);GO:0006821(chloride transport);GO:0015701(bicarbonate transport);GO:0034707(chloride channel complex);GO:1902476(chloride transmembrane transport);GO:0050896(response to stimulus);GO:0042802(identical protein binding);GO:0005229(intracellular calcium activated chloride channel activity);GO:0034220(ion transmembrane transport);GO:0016323(basolateral plasma membrane);GO:0005829(cytosol);GO:0015106(bicarbonate transmembrane transporter activity);GO:0030321(transepithelial chloride transport);GO:0050908(detection of light stimulus involved in visual perception);GO:0051924(regulation of calcium ion transport);GO:0051924(regulation of calcium ion transport)","NA","NA","NA","bestrophin 1 [Source:HGNC Symbol;Acc:HGNC:12703]",{"v":0.674156741881299,"d":"0.67"},{"v":1.86364559036954,"d":"1.86"},{"v":0.361740851031457,"d":"0.36"},{"v":-1.46697156558982,"d":"-1.47"},{"v":0.0327807851610365,"d":"0.03"},{"v":0.564729921186269,"d":"0.56"},"down","yes"]
["MSTRG.9090","MAP3K2","MSTRG.9090.2;ENST00000344908;ENST00000409947;ENST00000409179","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0000165(MAPK cascade);GO:0016310(phosphorylation);GO:0005515(protein binding);GO:0004709(MAP kinase kinase kinase activity);GO:0000187(activation of MAPK activity);GO:0045893(positive regulation of transcription, DNA-templated);GO:0000186(activation of MAPKK activity);GO:0019901(protein kinase binding);GO:0071260(cellular response to mechanical stimulus);GO:0042981(regulation of apoptotic process);GO:0007346(regulation of mitotic cell cycle);GO:0007257(activation of JUN kinase activity);GO:0005622(intracellular);GO:0005622(intracellular)","04010(MAPK signaling pathway);04540(Gap junction);04912(GnRH signaling pathway);04912(GnRH signaling pathway)","K04420","EC:2.7.11.25","mitogen-activated protein kinase kinase kinase 2 [Source:HGNC Symbol;Acc:HGNC:6854]",{"v":1.50200319015544,"d":"1.50"},{"v":4.10358635811744,"d":"4.10"},{"v":0.366022074126521,"d":"0.37"},{"v":-1.44999743743665,"d":"-1.45"},{"v":0.0330808794999352,"d":"0.03"},{"v":0.569085644197457,"d":"0.57"},"down","yes"]
["ENSG00000115042","FAHD2A","ENST00000233379;ENST00000447036;ENST00000418606;ENST00000463940;ENST00000445649;ENST00000470100","GO:0046872(metal ion binding);GO:0016787(hydrolase activity);GO:0003824(catalytic activity);GO:0008152(metabolic process);GO:0008152(metabolic process)","NA","NA","NA","fumarylacetoacetate hydrolase domain containing 2A [Source:HGNC Symbol;Acc:HGNC:24252]",{"v":1.63543911915269,"d":"1.64"},{"v":0.6098975929391,"d":"0.61"},{"v":2.68149790733146,"d":"2.68"},{"v":1.42303912746791,"d":"1.42"},{"v":0.033292812236024,"d":"0.03"},{"v":0.571732503286832,"d":"0.57"},"up","yes"]
["ENSG00000064763","FAR2","ENST00000536681;ENST00000547759;ENST00000551451;ENST00000550541;ENST00000549080;ENST00000551193;ENST00000182377","GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0006629(lipid metabolic process);GO:0080019(fatty-acyl-CoA reductase (alcohol-forming) activity);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005777(peroxisome);GO:0005778(peroxisomal membrane);GO:0005782(peroxisomal matrix);GO:0005779(integral component of peroxisomal membrane);GO:0010025(wax biosynthetic process);GO:0035336(long-chain fatty-acyl-CoA metabolic process);GO:0035336(long-chain fatty-acyl-CoA metabolic process)","00073(Cutin, suberine and wax biosynthesis);04146(Peroxisome);04146(Peroxisome)","K13356","EC:1.2.1.84","fatty acyl-CoA reductase 2 [Source:HGNC Symbol;Acc:HGNC:25531]",{"v":0.851309301238218,"d":"0.85"},{"v":2.33902446423951,"d":"2.34"},{"v":0.363959126658816,"d":"0.36"},{"v":-1.45815165291835,"d":"-1.46"},{"v":0.0333629250470097,"d":"0.03"},{"v":0.571732503286832,"d":"0.57"},"down","yes"]
["ENSG00000167676","PLIN4","ENST00000633942","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0043231(intracellular membrane-bounded organelle);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0005811(lipid particle)","03320(PPAR signaling pathway)","K20254","NA","perilipin 4 [Source:HGNC Symbol;Acc:HGNC:29393]",{"v":0.177506231313442,"d":"0.18"},{"v":0.504164407259305,"d":"0.50"},{"v":0.352080053168343,"d":"0.35"},{"v":-1.50602460017786,"d":"-1.51"},{"v":0.0333771757025945,"d":"0.03"},{"v":0.571732503286832,"d":"0.57"},"down","yes"]
["MSTRG.5943","CPNE2","ENST00000290776;ENST00000566042;ENST00000567011;ENST00000565951;ENST00000567487;ENST00000565874;ENST00000565766;ENST00000535318;ENST00000566910","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0070062(extracellular exosome);GO:0071277(cellular response to calcium ion);GO:0071277(cellular response to calcium ion)","NA","NA","NA","copine 2 [Source:HGNC Symbol;Acc:HGNC:2315]",{"v":1.18222489422953,"d":"1.18"},{"v":3.23344303984064,"d":"3.23"},{"v":0.365624159653604,"d":"0.37"},{"v":-1.45156669117396,"d":"-1.45"},{"v":0.0335474341176451,"d":"0.03"},{"v":0.572950947193772,"d":"0.57"},"down","yes"]
["ENSG00000162415","ZSWIM5","ENST00000359600","GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0005615(extracellular space)","NA","NA","NA","zinc finger SWIM-type containing 5 [Source:HGNC Symbol;Acc:HGNC:29299]",{"v":0.384424544988422,"d":"0.38"},{"v":0.137895670691366,"d":"0.14"},{"v":2.78779270633398,"d":"2.79"},{"v":1.4791232898066,"d":"1.48"},{"v":0.0335574815250582,"d":"0.03"},{"v":0.572950947193772,"d":"0.57"},"up","yes"]
["MSTRG.12279","CDC42SE2","ENST00000360515;MSTRG.12279.6;ENST00000505065;MSTRG.12279.7;ENST00000395246;ENST00000504701;ENST00000515533;ENST00000506419;ENST00000502840;ENST00000502639;MSTRG.12279.8;ENST00000511432;ENST00000503291;ENST00000506929","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005886(plasma membrane);GO:0005856(cytoskeleton);GO:0042995(cell projection);GO:0005515(protein binding);GO:0070062(extracellular exosome);GO:0001891(phagocytic cup);GO:0008360(regulation of cell shape);GO:0006909(phagocytosis);GO:0009966(regulation of signal transduction);GO:0005198(structural molecule activity);GO:0005198(structural molecule activity)","NA","NA","NA","CDC42 small effector 2 [Source:HGNC Symbol;Acc:HGNC:18547]",{"v":6.04675199311229,"d":"6.05"},{"v":16.4618326689092,"d":"16.46"},{"v":0.367319490771677,"d":"0.37"},{"v":-1.4448926442477,"d":"-1.44"},{"v":0.0335910454009968,"d":"0.03"},{"v":0.572950947193772,"d":"0.57"},"down","yes"]
["MSTRG.1391","MARC1","ENST00000366910;ENST00000496110;ENST00000407981;ENST00000443880;ENST00000472269;ENST00000492847;ENST00000463976","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0005739(mitochondrion);GO:0003824(catalytic activity);GO:0030170(pyridoxal phosphate binding);GO:0005741(mitochondrial outer membrane);GO:0030151(molybdenum ion binding);GO:0006805(xenobiotic metabolic process);GO:0043546(molybdopterin cofactor binding);GO:0008940(nitrate reductase activity);GO:0042126(nitrate metabolic process);GO:0051410(detoxification of nitrogen compound);GO:0005743(mitochondrial inner membrane);GO:0005743(mitochondrial inner membrane)","NA","NA","NA","mitochondrial amidoxime reducing component 1 [Source:HGNC Symbol;Acc:HGNC:26189]",{"v":2.01774307053359,"d":"2.02"},{"v":5.49482989479369,"d":"5.49"},{"v":0.367207558589828,"d":"0.37"},{"v":-1.44533233943676,"d":"-1.45"},{"v":0.0337778054519971,"d":"0.03"},{"v":0.574485899482757,"d":"0.57"},"down","yes"]
["MSTRG.12880","MPIG6B","ENST00000375809;MSTRG.12880.2;ENST00000375806;ENST00000471545;ENST00000466312;ENST00000460663;ENST00000485548;ENST00000480039;ENST00000375804;ENST00000375814","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005794(Golgi apparatus);GO:0005783(endoplasmic reticulum);GO:0005886(plasma membrane);GO:0030218(erythrocyte differentiation);GO:0007229(integrin-mediated signaling pathway);GO:0005515(protein binding);GO:0008201(heparin binding);GO:0007596(blood coagulation);GO:0030168(platelet activation);GO:0009968(negative regulation of signal transduction);GO:0030219(megakaryocyte differentiation);GO:0030220(platelet formation);GO:0035855(megakaryocyte development);GO:0035855(megakaryocyte development)","NA","NA","NA","megakaryocyte and platelet inhibitory receptor G6b [Source:HGNC Symbol;Acc:HGNC:13937]",{"v":18.9809317167355,"d":"18.98"},{"v":7.23717500889171,"d":"7.24"},{"v":2.62269900802664,"d":"2.62"},{"v":1.39105224734978,"d":"1.39"},{"v":0.0337988397307591,"d":"0.03"},{"v":0.574485899482757,"d":"0.57"},"up","yes"]
["MSTRG.14617","MROH6","ENST00000533679;ENST00000533083;ENST00000529971;ENST00000533210;ENST00000534459;ENST00000398882","NA","NA","NA","NA","maestro heat like repeat family member 6 [Source:HGNC Symbol;Acc:HGNC:27814]",{"v":0.196613264972777,"d":"0.20"},{"v":0.567757344600726,"d":"0.57"},{"v":0.346298056454109,"d":"0.35"},{"v":-1.52991380423899,"d":"-1.53"},{"v":0.0338420389660003,"d":"0.03"},{"v":0.574485899482757,"d":"0.57"},"down","yes"]
["MSTRG.9550","SIRPB1;SIRPD;AL049634.2;AL049634.1","ENST00000279477;ENST00000381605;ENST00000565076;ENST00000381603;ENST00000262929;ENST00000381623;MSTRG.9550.9;ENST00000381596;ENST00000564763;ENST00000565775;ENST00000563840;ENST00000381621;ENST00000453770;ENST00000566961;ENST00000567028","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005515(protein binding);GO:0005886(plasma membrane);GO:0070062(extracellular exosome);GO:0045087(innate immune response);GO:0005887(integral component of plasma membrane);GO:0043312(neutrophil degranulation);GO:0007165(signal transduction);GO:0007166(cell surface receptor signaling pathway);GO:0030667(secretory granule membrane);GO:0005576(extracellular region);GO:0005576(extracellular region)","04380(Osteoclast differentiation);04380(Osteoclast differentiation)","K06551","NA","signal regulatory protein beta 1 [Source:HGNC Symbol;Acc:HGNC:15928];signal regulatory protein delta [Source:HGNC Symbol;Acc:HGNC:16248]",{"v":6.00373510012386,"d":"6.00"},{"v":16.3040721385219,"d":"16.30"},{"v":0.368235312571927,"d":"0.37"},{"v":-1.44130011179113,"d":"-1.44"},{"v":0.033871864194715,"d":"0.03"},{"v":0.574485899482757,"d":"0.57"},"down","yes"]
["MSTRG.7275","SOCS3","ENST00000330871","GO:0005622(intracellular);GO:0043066(negative regulation of apoptotic process);GO:0016567(protein ubiquitination);GO:0035556(intracellular signal transduction);GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0007259(JAK-STAT cascade);GO:0005829(cytosol);GO:0040008(regulation of growth);GO:0043687(post-translational protein modification);GO:0019221(cytokine-mediated signaling pathway);GO:0006469(negative regulation of protein kinase activity);GO:0009968(negative regulation of signal transduction);GO:0046627(negative regulation of insulin receptor signaling pathway);GO:0001784(phosphotyrosine residue binding);GO:0004860(protein kinase inhibitor activity);GO:0001932(regulation of protein phosphorylation);GO:0042531(positive regulation of tyrosine phosphorylation of STAT protein);GO:0042532(negative regulation of tyrosine phosphorylation of STAT protein);GO:0045595(regulation of cell differentiation);GO:0045597(positive regulation of cell differentiation);GO:0046426(negative regulation of JAK-STAT cascade);GO:0050728(negative regulation of inflammatory response);GO:0060334(regulation of interferon-gamma-mediated signaling pathway);GO:0060670(branching involved in labyrinthine layer morphogenesis);GO:0060674(placenta blood vessel development);GO:0060707(trophoblast giant cell differentiation);GO:0060708(spongiotrophoblast differentiation);GO:1990830(cellular response to leukemia inhibitory factor)","04120(Ubiquitin mediated proteolysis);04630(Jak-STAT signaling pathway);04668(TNF signaling pathway);04910(Insulin signaling pathway);04920(Adipocytokine signaling pathway);04917(Prolactin signaling pathway);04380(Osteoclast differentiation);04930(Type II diabetes mellitus);04932(Non-alcoholic fatty liver disease (NAFLD));04931(Insulin resistance);05164(Influenza A);05160(Hepatitis C);05168(Herpes simplex infection)","K04696","NA","suppressor of cytokine signaling 3 [Source:HGNC Symbol;Acc:HGNC:19391]",{"v":3.919264,"d":"3.92"},{"v":10.666093,"d":"10.67"},{"v":0.367450761961292,"d":"0.37"},{"v":-1.4443771516959,"d":"-1.44"},{"v":0.0340864062661046,"d":"0.03"},{"v":0.577311539038581,"d":"0.58"},"down","yes"]
["MSTRG.11845","AC097376.2","ENST00000610159;ENST00000609359;ENST00000608661;ENST00000608663;ENST00000608345","NA","NA","NA","NA",null,{"v":0.281783068896153,"d":"0.28"},{"v":0.100386215866231,"d":"0.10"},{"v":2.80698964957142,"d":"2.81"},{"v":1.48902374409999,"d":"1.49"},{"v":0.0341597199010875,"d":"0.03"},{"v":0.577454389177318,"d":"0.58"},"up","yes"]
["MSTRG.2855","ZBTB16","ENST00000335953;ENST00000541602;ENST00000539918;ENST00000545851;ENST00000544220;ENST00000535700;ENST00000535509","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0016607(nuclear speck);GO:0046872(metal ion binding);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0016567(protein ubiquitination);GO:0003677(DNA binding);GO:0042803(protein homodimerization activity);GO:0005515(protein binding);GO:0006915(apoptotic process);GO:0003690(double-stranded DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0008022(protein C-terminus binding);GO:0019904(protein domain specific binding);GO:0001501(skeletal system development);GO:0001823(mesonephros development);GO:0007417(central nervous system development);GO:0008285(negative regulation of cell proliferation);GO:0009880(embryonic pattern specification);GO:0009952(anterior/posterior pattern specification);GO:0030097(hemopoiesis);GO:0034504(protein localization to nucleus);GO:0035116(embryonic hindlimb morphogenesis);GO:0035136(forelimb morphogenesis);GO:0035137(hindlimb morphogenesis);GO:0042733(embryonic digit morphogenesis);GO:0043065(positive regulation of apoptotic process);GO:0045638(negative regulation of myeloid cell differentiation);GO:0048133(male germ-line stem cell asymmetric division);GO:0051138(positive regulation of NK T cell differentiation);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0045893(positive regulation of transcription, DNA-templated);GO:0042802(identical protein binding);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0043687(post-translational protein modification);GO:0032332(positive regulation of chondrocyte differentiation);GO:0051216(cartilage development);GO:0045892(negative regulation of transcription, DNA-templated);GO:0016605(PML body);GO:0016604(nuclear body);GO:0045600(positive regulation of fat cell differentiation);GO:0000980(RNA polymerase II distal enhancer sequence-specific DNA binding);GO:0030099(myeloid cell differentiation);GO:0061036(positive regulation of cartilage development);GO:0045778(positive regulation of ossification);GO:0001206(transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding);GO:0017053(transcriptional repressor complex);GO:0017053(transcriptional repressor complex)","05200(Pathways in cancer);05202(Transcriptional misregulation in cancers);05221(Acute myeloid leukemia);05221(Acute myeloid leukemia)","K10055","NA","zinc finger and BTB domain containing 16 [Source:HGNC Symbol;Acc:HGNC:12930]",{"v":1.09569024387947,"d":"1.10"},{"v":0.410446420747018,"d":"0.41"},{"v":2.66950858503115,"d":"2.67"},{"v":1.41657418865852,"d":"1.42"},{"v":0.0341907473412579,"d":"0.03"},{"v":0.577454389177318,"d":"0.58"},"up","yes"]
["MSTRG.7040","TRIM25;MIR3614","ENST00000316881;MSTRG.7040.1;ENST00000570749;ENST00000574234;ENST00000581261;ENST00000572550;ENST00000572021;ENST00000570473;ENST00000574997;ENST00000573108;ENST00000537230","GO:0003723(RNA binding);GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0016740(transferase activity);GO:0016567(protein ubiquitination);GO:0016874(ligase activity);GO:0005515(protein binding);GO:0016604(nuclear body);GO:0002376(immune system process);GO:0045087(innate immune response);GO:0051607(defense response to virus);GO:1904264(ubiquitin protein ligase activity involved in ERAD pathway);GO:0045296(cadherin binding);GO:0016579(protein deubiquitination);GO:0016032(viral process);GO:0042787(protein ubiquitination involved in ubiquitin-dependent protein catabolic process);GO:0043123(positive regulation of I-kappaB kinase/NF-kappaB signaling);GO:0051092(positive regulation of NF-kappaB transcription factor activity);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0051091(positive regulation of sequence-specific DNA binding transcription factor activity);GO:0060333(interferon-gamma-mediated signaling pathway);GO:0043627(response to estrogen);GO:0019985(translesion synthesis);GO:0032480(negative regulation of type I interferon production);GO:0004842(ubiquitin-protein transferase activity);GO:0006513(protein monoubiquitination);GO:0030433(ubiquitin-dependent ERAD pathway);GO:0036503(ERAD pathway);GO:0033280(response to vitamin D);GO:0046596(regulation of viral entry into host cell);GO:0046597(negative regulation of viral entry into host cell);GO:1902186(regulation of viral release from host cell);GO:1902187(negative regulation of viral release from host cell);GO:1990830(cellular response to leukemia inhibitory factor);GO:1990830(cellular response to leukemia inhibitory factor)","04064(NF-kappa B signaling pathway);04622(RIG-I-like receptor signaling pathway);05164(Influenza A);05164(Influenza A)","K10652","EC:2.3.2.27","tripartite motif containing 25 [Source:HGNC Symbol;Acc:HGNC:12932];microRNA 3614 [Source:HGNC Symbol;Acc:HGNC:38995]",{"v":2.81262095359281,"d":"2.81"},{"v":7.63746220318454,"d":"7.64"},{"v":0.368266431802445,"d":"0.37"},{"v":-1.44117819610005,"d":"-1.44"},{"v":0.0343045560059216,"d":"0.03"},{"v":0.57856507482256,"d":"0.58"},"down","yes"]
["MSTRG.9899","SAMD10","ENST00000369886;ENST00000450107;ENST00000498830;ENST00000478694","NA","NA","NA","NA","sterile alpha motif domain containing 10 [Source:HGNC Symbol;Acc:HGNC:16129]",{"v":5.01117211251529,"d":"5.01"},{"v":1.90079176192417,"d":"1.90"},{"v":2.63636039091546,"d":"2.64"},{"v":1.39854760048532,"d":"1.40"},{"v":0.0344953371877516,"d":"0.03"},{"v":0.580969021559307,"d":"0.58"},"up","yes"]
["MSTRG.5340","MTHFS;ST20;ST20-MTHFS","ENST00000258874;ENST00000560919;ENST00000478497;ENST00000479961;ENST00000485386;ENST00000559722;ENST00000562759;ENST00000615374;ENST00000560261;ENST00000494999","GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0005829(cytosol);GO:0016874(ligase activity);GO:0030272(5-formyltetrahydrofolate cyclo-ligase activity);GO:0009396(folic acid-containing compound biosynthetic process);GO:0005759(mitochondrial matrix);GO:0046655(folic acid metabolic process);GO:0005542(folic acid binding);GO:0046653(tetrahydrofolate metabolic process);GO:0035999(tetrahydrofolate interconversion);GO:0006536(glutamate metabolic process);GO:0015942(formate metabolic process);GO:0046657(folic acid catabolic process);GO:0005739(mitochondrion);GO:0035999(tetrahydrofolate interconversion)","00670(One carbon pool by folate);00670(One carbon pool by folate)","K01934","EC:6.3.3.2","methenyltetrahydrofolate synthetase [Source:HGNC Symbol;Acc:HGNC:7437];suppressor of tumorigenicity 20 [Source:HGNC Symbol;Acc:HGNC:33520];ST20-MTHFS readthrough [Source:HGNC Symbol;Acc:HGNC:44655]",{"v":3.38672575675676,"d":"3.39"},{"v":9.20098352123552,"d":"9.20"},{"v":0.368083015140754,"d":"0.37"},{"v":-1.44189691549289,"d":"-1.44"},{"v":0.0345726288588746,"d":"0.03"},{"v":0.581457537316436,"d":"0.58"},"down","yes"]
["MSTRG.2003","PRDX3","ENST00000298510;ENST00000494433;ENST00000463322","GO:0005737(cytoplasm);GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0045454(cell redox homeostasis);GO:0005739(mitochondrion);GO:0005515(protein binding);GO:0098869(cellular oxidant detoxification);GO:0004601(peroxidase activity);GO:0051920(peroxiredoxin activity);GO:0016209(antioxidant activity);GO:0070062(extracellular exosome);GO:0019901(protein kinase binding);GO:0042744(hydrogen peroxide catabolic process);GO:0005759(mitochondrial matrix);GO:0032496(response to lipopolysaccharide);GO:0043234(protein complex);GO:0005769(early endosome);GO:0008022(protein C-terminus binding);GO:0008284(positive regulation of cell proliferation);GO:0043066(negative regulation of apoptotic process);GO:0051092(positive regulation of NF-kappaB transcription factor activity);GO:0006979(response to oxidative stress);GO:0005829(cytosol);GO:0042542(response to hydrogen peroxide);GO:0034599(cellular response to oxidative stress);GO:0008385(IkappaB kinase complex);GO:0007005(mitochondrion organization);GO:0019900(kinase binding);GO:0043027(cysteine-type endopeptidase inhibitor activity involved in apoptotic process);GO:0043154(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process);GO:0051881(regulation of mitochondrial membrane potential);GO:0006915(apoptotic process);GO:0034614(cellular response to reactive oxygen species);GO:0008379(thioredoxin peroxidase activity);GO:0008785(alkyl hydroperoxide reductase activity);GO:0042802(identical protein binding);GO:0001893(maternal placenta development);GO:0018171(peptidyl-cysteine oxidation);GO:0030099(myeloid cell differentiation);GO:0033673(negative regulation of kinase activity);GO:0043209(myelin sheath);GO:0043209(myelin sheath)","NA","NA","NA","peroxiredoxin 3 [Source:HGNC Symbol;Acc:HGNC:9354]",{"v":2.84190426397425,"d":"2.84"},{"v":7.72680028650863,"d":"7.73"},{"v":0.367798332892899,"d":"0.37"},{"v":-1.44301315437785,"d":"-1.44"},{"v":0.0346586180948243,"d":"0.03"},{"v":0.5817954663125,"d":"0.58"},"down","yes"]
["ENSG00000167333","TRIM68","ENST00000300747;ENST00000532108;ENST00000526337;ENST00000531644;ENST00000531717;ENST00000531101","GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0005622(intracellular);GO:0005794(Golgi apparatus);GO:0005634(nucleus);GO:0005730(nucleolus);GO:0005829(cytosol);GO:0005737(cytoplasm);GO:0016740(transferase activity);GO:0016567(protein ubiquitination);GO:0048471(perinuclear region of cytoplasm);GO:0004842(ubiquitin-protein transferase activity);GO:0060333(interferon-gamma-mediated signaling pathway);GO:0050681(androgen receptor binding);GO:0051865(protein autoubiquitination);GO:0035035(histone acetyltransferase binding);GO:0060765(regulation of androgen receptor signaling pathway);GO:0060765(regulation of androgen receptor signaling pathway)","NA","NA","NA","tripartite motif containing 68 [Source:HGNC Symbol;Acc:HGNC:21161]",{"v":2.08078444091546,"d":"2.08"},{"v":0.784925521952359,"d":"0.78"},{"v":2.65093232761739,"d":"2.65"},{"v":1.40649984189248,"d":"1.41"},{"v":0.0346893493449904,"d":"0.03"},{"v":0.5817954663125,"d":"0.58"},"up","yes"]
["MSTRG.1101","MNDA","ENST00000491210;ENST00000438394;ENST00000368141","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005730(nucleolus);GO:0005654(nucleoplasm);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0006974(cellular response to DNA damage stimulus);GO:0005576(extracellular region);GO:0070062(extracellular exosome);GO:0043065(positive regulation of apoptotic process);GO:0043312(neutrophil degranulation);GO:1904813(ficolin-1-rich granule lumen);GO:0050853(B cell receptor signaling pathway);GO:0035578(azurophil granule lumen);GO:0006968(cellular defense response);GO:0030889(negative regulation of B cell proliferation);GO:0030889(negative regulation of B cell proliferation)","NA","NA","NA","myeloid cell nuclear differentiation antigen [Source:HGNC Symbol;Acc:HGNC:7183]",{"v":212.568997849442,"d":"212.57"},{"v":573.124450138417,"d":"573.12"},{"v":0.370895008576416,"d":"0.37"},{"v":-1.43091724238887,"d":"-1.43"},{"v":0.0348687158161243,"d":"0.03"},{"v":0.58322563031398,"d":"0.58"},"down","yes"]
["ENSG00000077585","GPR137B","ENST00000366592;ENST00000366591;ENST00000454895;ENST00000419162","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005765(lysosomal membrane);GO:0005764(lysosome);GO:0005887(integral component of plasma membrane);GO:0005887(integral component of plasma membrane)","NA","NA","NA","G protein-coupled receptor 137B [Source:HGNC Symbol;Acc:HGNC:11862]",{"v":3.32376499307059,"d":"3.32"},{"v":1.25312472585535,"d":"1.25"},{"v":2.65238162211018,"d":"2.65"},{"v":1.40728836395601,"d":"1.41"},{"v":0.0348714876121961,"d":"0.03"},{"v":0.58322563031398,"d":"0.58"},"up","yes"]
["ENSG00000214900","LINC01588","ENST00000533506;ENST00000557142;ENST00000554129;ENST00000553463;ENST00000530176;ENST00000529902;ENST00000556019;ENST00000556913;ENST00000528300;ENST00000399206;ENST00000635379;ENST00000553914;ENST00000556434;ENST00000623502","NA","NA","NA","NA","long intergenic non-protein coding RNA 1588 [Source:HGNC Symbol;Acc:HGNC:27503]",{"v":0.307165403711983,"d":"0.31"},{"v":0.112177215064689,"d":"0.11"},{"v":2.73821563081995,"d":"2.74"},{"v":1.45323606137497,"d":"1.45"},{"v":0.0349659912719982,"d":"0.03"},{"v":0.583995099719004,"d":"0.58"},"up","yes"]
["MSTRG.9021","AC007278.1","ENST00000450893","NA","NA","NA","NA",null,{"v":1.545911,"d":"1.55"},{"v":0.550543,"d":"0.55"},{"v":2.80797503555581,"d":"2.81"},{"v":1.4895301093462,"d":"1.49"},{"v":0.0352171422485196,"d":"0.04"},{"v":0.586737967512112,"d":"0.59"},"up","yes"]
["ENSG00000188486","H2AFX","ENST00000530167;ENST00000375167","GO:0005634(nucleus);GO:0016607(nuclear speck);GO:0005654(nucleoplasm);GO:0003677(DNA binding);GO:0046982(protein heterodimerization activity);GO:0006334(nucleosome assembly);GO:0000786(nucleosome);GO:0005694(chromosome);GO:0005515(protein binding);GO:0006281(DNA repair);GO:0006310(DNA recombination);GO:0006974(cellular response to DNA damage stimulus);GO:0007049(cell cycle);GO:0051321(meiotic cell cycle);GO:0005813(centrosome);GO:0000790(nuclear chromatin);GO:0070062(extracellular exosome);GO:0016032(viral process);GO:0019899(enzyme binding);GO:0042393(histone binding);GO:0000781(chromosome, telomeric region);GO:0000077(DNA damage checkpoint);GO:0006342(chromatin silencing);GO:0045739(positive regulation of DNA repair);GO:0006302(double-strand break repair);GO:0006303(double-strand break repair via nonhomologous end joining);GO:0010212(response to ionizing radiation);GO:0007283(spermatogenesis);GO:0021987(cerebral cortex development);GO:0071480(cellular response to gamma radiation);GO:0090398(cellular senescence);GO:0035861(site of double-strand break);GO:0035861(site of double-strand break)","04217(Necroptosis);05322(Systemic lupus erythematosus);05034(Alcoholism);05034(Alcoholism)","K11251","NA","H2A histone family member X [Source:HGNC Symbol;Acc:HGNC:4739]",{"v":1.44821,"d":"1.45"},{"v":3.968579,"d":"3.97"},{"v":0.364919030212073,"d":"0.36"},{"v":-1.45435170670352,"d":"-1.45"},{"v":0.0352696541322873,"d":"0.04"},{"v":0.586737967512112,"d":"0.59"},"down","yes"]
["MSTRG.8844","LOXL3","ENST00000264094;ENST00000470907;ENST00000409549;ENST00000413469;ENST00000481835;ENST00000409986","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0046872(metal ion binding);GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0005576(extracellular region);GO:0005044(scavenger receptor activity);GO:0006898(receptor-mediated endocytosis);GO:0005615(extracellular space);GO:0006954(inflammatory response);GO:0005507(copper ion binding);GO:0005515(protein binding);GO:0001968(fibronectin binding);GO:0016641(oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor);GO:0045892(negative regulation of transcription, DNA-templated);GO:0060021(palate development);GO:0021510(spinal cord development);GO:0001837(epithelial to mesenchymal transition);GO:2001046(positive regulation of integrin-mediated signaling pathway);GO:0030324(lung development);GO:0004720(protein-lysine 6-oxidase activity);GO:0061053(somite development);GO:0018057(peptidyl-lysine oxidation);GO:1905590(fibronectin fibril organization);GO:2000329(negative regulation of T-helper 17 cell lineage commitment);GO:2000329(negative regulation of T-helper 17 cell lineage commitment)","NA","NA","NA","lysyl oxidase like 3 [Source:HGNC Symbol;Acc:HGNC:13869]",{"v":0.496992712353885,"d":"0.50"},{"v":1.36543770685308,"d":"1.37"},{"v":0.363980509590073,"d":"0.36"},{"v":-1.4580668957562,"d":"-1.46"},{"v":0.0352763900082021,"d":"0.04"},{"v":0.586737967512112,"d":"0.59"},"down","yes"]
["MSTRG.10373","RNF185","ENST00000326132;ENST00000494514;ENST00000266252;ENST00000426256;ENST00000468921;ENST00000471384;ENST00000518626","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0046872(metal ion binding);GO:0016740(transferase activity);GO:0016567(protein ubiquitination);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005739(mitochondrion);GO:0005515(protein binding);GO:0044322(endoplasmic reticulum quality control compartment);GO:0005741(mitochondrial outer membrane);GO:0006914(autophagy);GO:1904264(ubiquitin protein ligase activity involved in ERAD pathway);GO:0030433(ubiquitin-dependent ERAD pathway);GO:0055085(transmembrane transport);GO:0042787(protein ubiquitination involved in ubiquitin-dependent protein catabolic process);GO:1904380(endoplasmic reticulum mannose trimming);GO:0036503(ERAD pathway);GO:0051865(protein autoubiquitination);GO:0036513(Derlin-1 retrotranslocation complex);GO:0044390(ubiquitin-like protein conjugating enzyme binding);GO:0071712(ER-associated misfolded protein catabolic process);GO:0071712(ER-associated misfolded protein catabolic process)","04141(Protein processing in endoplasmic reticulum);04141(Protein processing in endoplasmic reticulum)","K10666","EC:2.3.2.27","ring finger protein 185 [Source:HGNC Symbol;Acc:HGNC:26783]",{"v":5.02566784711343,"d":"5.03"},{"v":1.92124865651291,"d":"1.92"},{"v":2.61583415039836,"d":"2.62"},{"v":1.38727107371719,"d":"1.39"},{"v":0.0353730606104561,"d":"0.04"},{"v":0.587534339132569,"d":"0.59"},"up","yes"]
["MSTRG.12697","RNF144B","ENST00000259939;ENST00000486622","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0046872(metal ion binding);GO:0016740(transferase activity);GO:0016567(protein ubiquitination);GO:0004842(ubiquitin-protein transferase activity);GO:0005739(mitochondrion);GO:0005515(protein binding);GO:0006915(apoptotic process);GO:0031966(mitochondrial membrane);GO:0000151(ubiquitin ligase complex);GO:0061630(ubiquitin protein ligase activity);GO:0005829(cytosol);GO:0000209(protein polyubiquitination);GO:0042787(protein ubiquitination involved in ubiquitin-dependent protein catabolic process);GO:0043066(negative regulation of apoptotic process);GO:0032436(positive regulation of proteasomal ubiquitin-dependent protein catabolic process);GO:0031624(ubiquitin conjugating enzyme binding);GO:0031624(ubiquitin conjugating enzyme binding)","NA","NA","NA","ring finger protein 144B [Source:HGNC Symbol;Acc:HGNC:21578]",{"v":2.9902901905314,"d":"2.99"},{"v":8.06125900676328,"d":"8.06"},{"v":0.370945802389253,"d":"0.37"},{"v":-1.43071967983658,"d":"-1.43"},{"v":0.0354740310458514,"d":"0.04"},{"v":0.588096994882474,"d":"0.59"},"down","yes"]
["MSTRG.7627","MKNK2","MSTRG.7627.8;MSTRG.7627.1;ENST00000591601;ENST00000586828;ENST00000588014;ENST00000591142;ENST00000585667;ENST00000586620;ENST00000589441;ENST00000591588;ENST00000587416","GO:0004672(protein kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0004674(protein serine/threonine kinase activity);GO:0005730(nucleolus);GO:0016740(transferase activity);GO:0005515(protein binding);GO:0016604(nuclear body);GO:0006915(apoptotic process);GO:0006417(regulation of translation);GO:0005516(calmodulin binding);GO:0018105(peptidyl-serine phosphorylation);GO:0007166(cell surface receptor signaling pathway);GO:0016605(PML body);GO:0030097(hemopoiesis);GO:0035556(intracellular signal transduction);GO:0071243(cellular response to arsenic-containing substance);GO:0004683(calmodulin-dependent protein kinase activity);GO:0009931(calcium-dependent protein serine/threonine kinase activity);GO:0046777(protein autophosphorylation);GO:0097192(extrinsic apoptotic signaling pathway in absence of ligand);GO:0097192(extrinsic apoptotic signaling pathway in absence of ligand)","04010(MAPK signaling pathway);04066(HIF-1 signaling pathway);04910(Insulin signaling pathway);04910(Insulin signaling pathway)","NA","NA","MAP kinase interacting serine/threonine kinase 2 [Source:HGNC Symbol;Acc:HGNC:7111]",{"v":15.4735409653015,"d":"15.47"},{"v":41.617163761661,"d":"41.62"},{"v":0.371806715467626,"d":"0.37"},{"v":-1.42737526684528,"d":"-1.43"},{"v":0.0355046101378142,"d":"0.04"},{"v":0.588096994882474,"d":"0.59"},"down","yes"]
["MSTRG.15181","AP1S2","ENST00000380291;ENST00000329235;ENST00000545766;ENST00000452376;ENST00000479184;ENST00000450644","GO:0006810(transport);GO:0016020(membrane);GO:0008565(protein transporter activity);GO:0006886(intracellular protein transport);GO:0015031(protein transport);GO:0016192(vesicle-mediated transport);GO:0005794(Golgi apparatus);GO:0030117(membrane coat);GO:0043231(intracellular membrane-bounded organelle);GO:0005515(protein binding);GO:0030659(cytoplasmic vesicle membrane);GO:0031410(cytoplasmic vesicle);GO:0005905(clathrin-coated pit);GO:0005829(cytosol);GO:0019886(antigen processing and presentation of exogenous peptide antigen via MHC class II);GO:0030119(AP-type membrane coat adaptor complex);GO:0032588(trans-Golgi network membrane);GO:0000139(Golgi membrane);GO:0005765(lysosomal membrane);GO:0050690(regulation of defense response to virus by virus);GO:0030669(clathrin-coated endocytic vesicle membrane);GO:0030669(clathrin-coated endocytic vesicle membrane)","04142(Lysosome);04142(Lysosome)","K12394","NA","adaptor related protein complex 1 sigma 2 subunit [Source:HGNC Symbol;Acc:HGNC:560]",{"v":6.96353242748092,"d":"6.96"},{"v":18.724975531186,"d":"18.72"},{"v":0.371884727746817,"d":"0.37"},{"v":-1.42707259312285,"d":"-1.43"},{"v":0.0355874975204834,"d":"0.04"},{"v":0.58838498240785,"d":"0.59"},"down","yes"]
["MSTRG.9481","AC010149.1","MSTRG.9481.1","NA","NA","NA","NA",null,{"v":11.508205,"d":"11.51"},{"v":4.179591,"d":"4.18"},{"v":2.75342850532504,"d":"2.75"},{"v":1.46122914840086,"d":"1.46"},{"v":0.0356197186659461,"d":"0.04"},{"v":0.58838498240785,"d":"0.59"},"up","yes"]
["ENSG00000153029","MR1","ENST00000282990;ENST00000434571;ENST00000367580;ENST00000438435;ENST00000367579;ENST00000614012;ENST00000486453;ENST00000367578","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005886(plasma membrane);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0002376(immune system process);GO:0045087(innate immune response);GO:0007165(signal transduction);GO:0002474(antigen processing and presentation of peptide antigen via MHC class I);GO:0042612(MHC class I protein complex);GO:0006955(immune response);GO:0032393(MHC class I receptor activity);GO:0002367(cytokine production involved in immune response);GO:0032611(interleukin-1 beta production);GO:0032620(interleukin-17 production);GO:0050829(defense response to Gram-negative bacterium);GO:0050829(defense response to Gram-negative bacterium)","NA","NA","NA","major histocompatibility complex, class I-related [Source:HGNC Symbol;Acc:HGNC:4975]",{"v":2.67592469875909,"d":"2.68"},{"v":1.02840927845528,"d":"1.03"},{"v":2.60200365245484,"d":"2.60"},{"v":1.37962298718053,"d":"1.38"},{"v":0.0357874405397183,"d":"0.04"},{"v":0.590345697231902,"d":"0.59"},"up","yes"]
["MSTRG.10110","BID","ENST00000317361;ENST00000399774;ENST00000622694;ENST00000617586;ENST00000614949;ENST00000473439;ENST00000550946;ENST00000399767;ENST00000342111;ENST00000399765;ENST00000611040;ENST00000494097;ENST00000551952","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005829(cytosol);GO:0042981(regulation of apoptotic process);GO:0005739(mitochondrion);GO:0005515(protein binding);GO:0006915(apoptotic process);GO:0043065(positive regulation of apoptotic process);GO:0031966(mitochondrial membrane);GO:0070062(extracellular exosome);GO:0032464(positive regulation of protein homooligomerization);GO:0090200(positive regulation of release of cytochrome c from mitochondria);GO:0008625(extrinsic apoptotic signaling pathway via death domain receptors);GO:0005741(mitochondrial outer membrane);GO:0032461(positive regulation of protein oligomerization);GO:1900740(positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway);GO:2001238(positive regulation of extrinsic apoptotic signaling pathway);GO:2001244(positive regulation of intrinsic apoptotic signaling pathway);GO:0042770(signal transduction in response to DNA damage);GO:0001836(release of cytochrome c from mitochondria);GO:0051402(neuron apoptotic process);GO:0005123(death receptor binding);GO:0031625(ubiquitin protein ligase binding);GO:0046982(protein heterodimerization activity);GO:0006626(protein targeting to mitochondrion);GO:0006919(activation of cysteine-type endopeptidase activity involved in apoptotic process);GO:0007420(brain development);GO:0008637(apoptotic mitochondrial changes);GO:0010918(positive regulation of mitochondrial membrane potential);GO:0032355(response to estradiol);GO:0032459(regulation of protein oligomerization);GO:0034349(glial cell apoptotic process);GO:0042127(regulation of cell proliferation);GO:0042775(mitochondrial ATP synthesis coupled electron transport);GO:0051260(protein homooligomerization);GO:0090150(establishment of protein localization to membrane);GO:0097191(extrinsic apoptotic signaling pathway);GO:0097284(hepatocyte apoptotic process);GO:0097345(mitochondrial outer membrane permeabilization);GO:1901030(positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway);GO:1902108(regulation of mitochondrial membrane permeability involved in apoptotic process);GO:1902230(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage);GO:2000045(regulation of G1/S transition of mitotic cell cycle);GO:2000271(positive regulation of fibroblast apoptotic process);GO:2001235(positive regulation of apoptotic signaling pathway);GO:0032592(integral component of mitochondrial membrane);GO:0032592(integral component of mitochondrial membrane)","04071(Sphingolipid signaling pathway);04210(Apoptosis);04215(Apoptosis - multiple species);04217(Necroptosis);04115(p53 signaling pathway);04650(Natural killer cell mediated cytotoxicity);05200(Pathways in cancer);05010(Alzheimer's disease);05014(Amyotrophic lateral sclerosis (ALS));05416(Viral myocarditis);04932(Non-alcoholic fatty liver disease (NAFLD));05152(Tuberculosis);05167(Kaposi's sarcoma-associated herpesvirus infection);01524(Platinum drug resistance);01524(Platinum drug resistance)","K04726","NA","BH3 interacting domain death agonist [Source:HGNC Symbol;Acc:HGNC:1050]",{"v":3.3376490665767,"d":"3.34"},{"v":8.9865886448493,"d":"8.99"},{"v":0.37140334319071,"d":"0.37"},{"v":-1.42894129312251,"d":"-1.43"},{"v":0.0360893618555418,"d":"0.04"},{"v":0.593224332755144,"d":"0.59"},"down","yes"]
["ENSG00000226137","BAIAP2-AS1","ENST00000573167;ENST00000577066","NA","NA","NA","NA","BAIAP2 antisense RNA 1 (head to head) [Source:HGNC Symbol;Acc:HGNC:44342]",{"v":0.437528764927718,"d":"0.44"},{"v":1.20095802011314,"d":"1.20"},{"v":0.364316452032602,"d":"0.36"},{"v":-1.45673594820108,"d":"-1.46"},{"v":0.0361074915414317,"d":"0.04"},{"v":0.593224332755144,"d":"0.59"},"down","yes"]
["MSTRG.3624","AC007298.2","MSTRG.3624.1;ENST00000551849","NA","NA","NA","NA",null,{"v":5.35559600878156,"d":"5.36"},{"v":14.4765531997805,"d":"14.48"},{"v":0.369949665149765,"d":"0.37"},{"v":-1.43459910192614,"d":"-1.43"},{"v":0.0361097355845807,"d":"0.04"},{"v":0.593224332755144,"d":"0.59"},"down","yes"]
["MSTRG.2424","FABP5P7","ENST00000524732","NA","NA","NA","NA","fatty acid binding protein 5 pseudogene 7 [Source:HGNC Symbol;Acc:HGNC:31070]",{"v":7.138046,"d":"7.14"},{"v":2.635977,"d":"2.64"},{"v":2.70793182186339,"d":"2.71"},{"v":1.43719141635095,"d":"1.44"},{"v":0.0362548529295025,"d":"0.04"},{"v":0.593661117938102,"d":"0.59"},"up","yes"]
["MSTRG.6447","MAP2K4","ENST00000353533;ENST00000585076;ENST00000602686;ENST00000602375;ENST00000536413;ENST00000602305;ENST00000582377","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0004713(protein tyrosine kinase activity);GO:0018108(peptidyl-tyrosine phosphorylation);GO:0005515(protein binding);GO:0006915(apoptotic process);GO:0038095(Fc-epsilon receptor signaling pathway);GO:0005829(cytosol);GO:0007165(signal transduction);GO:0071260(cellular response to mechanical stimulus);GO:0042981(regulation of apoptotic process);GO:0007346(regulation of mitotic cell cycle);GO:0007254(JNK cascade);GO:0035897(proteolysis in other organism);GO:0031098(stress-activated protein kinase signaling cascade);GO:0023014(signal transduction by protein phosphorylation);GO:0032147(activation of protein kinase activity);GO:0004708(MAP kinase kinase activity);GO:0008545(JUN kinase kinase activity);GO:0031435(mitogen-activated protein kinase kinase kinase binding);GO:0000165(MAPK cascade);GO:0001934(positive regulation of protein phosphorylation);GO:0007257(activation of JUN kinase activity);GO:0009611(response to wounding);GO:0034393(positive regulation of smooth muscle cell apoptotic process);GO:0043065(positive regulation of apoptotic process);GO:0043525(positive regulation of neuron apoptotic process);GO:0045740(positive regulation of DNA replication);GO:0051770(positive regulation of nitric-oxide synthase biosynthetic process);GO:0061049(cell growth involved in cardiac muscle cell development);GO:0072709(cellular response to sorbitol);GO:2000672(negative regulation of motor neuron apoptotic process);GO:0030424(axon);GO:0032839(dendrite cytoplasm);GO:0043204(perikaryon);GO:0043204(perikaryon)","04010(MAPK signaling pathway);04012(ErbB signaling pathway);04668(TNF signaling pathway);04620(Toll-like receptor signaling pathway);04664(Fc epsilon RI signaling pathway);04912(GnRH signaling pathway);04926(Relaxin signaling pathway);05418(Fluid shear stress and atherosclerosis);05120(Epithelial cell signaling in Helicobacter pylori infection);05166(HTLV-I infection);05164(Influenza A);05161(Hepatitis B);05167(Kaposi's sarcoma-associated herpesvirus infection);05169(Epstein-Barr virus infection);05142(Chagas disease (American trypanosomiasis));05142(Chagas disease (American trypanosomiasis))","K04430","EC:2.7.12.2","mitogen-activated protein kinase kinase 4 [Source:HGNC Symbol;Acc:HGNC:6844]",{"v":2.98230471613581,"d":"2.98"},{"v":7.99534079523976,"d":"8.00"},{"v":0.373005328041977,"d":"0.37"},{"v":-1.4227318566727,"d":"-1.42"},{"v":0.0363619659727656,"d":"0.04"},{"v":0.593661117938102,"d":"0.59"},"down","yes"]
["MSTRG.11699","GPAT3","ENST00000264409;ENST00000509412;ENST00000509044;ENST00000395226","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016740(transferase activity);GO:0016746(transferase activity, transferring acyl groups);GO:0006629(lipid metabolic process);GO:0008152(metabolic process);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0008654(phospholipid biosynthetic process);GO:0003841(1-acylglycerol-3-phosphate O-acyltransferase activity);GO:0016024(CDP-diacylglycerol biosynthetic process);GO:0006654(phosphatidic acid biosynthetic process);GO:0032006(regulation of TOR signaling);GO:0019432(triglyceride biosynthetic process);GO:0004366(glycerol-3-phosphate O-acyltransferase activity);GO:0102420(sn-1-glycerol-3-phosphate C16:0-DCA-CoA acyl transferase activity);GO:0102420(sn-1-glycerol-3-phosphate C16:0-DCA-CoA acyl transferase activity)","00561(Glycerolipid metabolism);00564(Glycerophospholipid metabolism);00564(Glycerophospholipid metabolism)","K13506","EC:2.3.1.15","glycerol-3-phosphate acyltransferase 3 [Source:HGNC Symbol;Acc:HGNC:28157]",{"v":3.50561620991926,"d":"3.51"},{"v":9.42133095991926,"d":"9.42"},{"v":0.372093521056955,"d":"0.37"},{"v":-1.42626282460744,"d":"-1.43"},{"v":0.036373694943549,"d":"0.04"},{"v":0.593661117938102,"d":"0.59"},"down","yes"]
["ENSG00000143797","MBOAT2","ENST00000305997;ENST00000486315;ENST00000474341;ENST00000460786;ENST00000473432;ENST00000494760;ENST00000486484;ENST00000471753","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016740(transferase activity);GO:0016746(transferase activity, transferring acyl groups);GO:0006629(lipid metabolic process);GO:0008654(phospholipid biosynthetic process);GO:0003841(1-acylglycerol-3-phosphate O-acyltransferase activity);GO:0005789(endoplasmic reticulum membrane);GO:0006644(phospholipid metabolic process);GO:0036151(phosphatidylcholine acyl-chain remodeling);GO:0036152(phosphatidylethanolamine acyl-chain remodeling);GO:0047144(2-acylglycerol-3-phosphate O-acyltransferase activity);GO:0047144(2-acylglycerol-3-phosphate O-acyltransferase activity)","00561(Glycerolipid metabolism);00564(Glycerophospholipid metabolism);00564(Glycerophospholipid metabolism)","K13517","EC:2.3.1.51;EC:2.3.1.-","membrane bound O-acyltransferase domain containing 2 [Source:HGNC Symbol;Acc:HGNC:25193]",{"v":0.583200662650602,"d":"0.58"},{"v":1.57536207808593,"d":"1.58"},{"v":0.370201029187647,"d":"0.37"},{"v":-1.43361918886891,"d":"-1.43"},{"v":0.0364105804746749,"d":"0.04"},{"v":0.593661117938102,"d":"0.59"},"down","yes"]
["ENSG00000234420","ZNF37BP","ENST00000452075;ENST00000435805;ENST00000473592","NA","NA","NA","NA","zinc finger protein 37B, pseudogene [Source:HGNC Symbol;Acc:HGNC:13103]",{"v":1.2685756274376,"d":"1.27"},{"v":0.486821869344774,"d":"0.49"},{"v":2.60583122353359,"d":"2.61"},{"v":1.38174364535796,"d":"1.38"},{"v":0.0364320405353893,"d":"0.04"},{"v":0.593661117938102,"d":"0.59"},"up","yes"]
["MSTRG.10421","NCF4","ENST00000248899;ENST00000397147;ENST00000415063;ENST00000447071","GO:0043085(positive regulation of catalytic activity);GO:0035091(phosphatidylinositol binding);GO:0006909(phagocytosis);GO:0016176(superoxide-generating NADPH oxidase activator activity);GO:0045730(respiratory burst);GO:0043020(NADPH oxidase complex);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005829(cytosol);GO:0055114(oxidation-reduction process);GO:0043547(positive regulation of GTPase activity);GO:0005515(protein binding);GO:0006955(immune response);GO:0008289(lipid binding);GO:0005768(endosome);GO:0032266(phosphatidylinositol-3-phosphate binding);GO:0002479(antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent);GO:0016192(vesicle-mediated transport);GO:0010008(endosome membrane);GO:0005802(trans-Golgi network);GO:0048010(vascular endothelial growth factor receptor signaling pathway);GO:0034599(cellular response to oxidative stress);GO:0046983(protein dimerization activity);GO:0045454(cell redox homeostasis);GO:0032010(phagolysosome);GO:0005086(ARF guanyl-nucleotide exchange factor activity);GO:0005086(ARF guanyl-nucleotide exchange factor activity)","04145(Phagosome);04670(Leukocyte transendothelial migration);04380(Osteoclast differentiation);05140(Leishmaniasis);05140(Leishmaniasis)","K08012","NA","neutrophil cytosolic factor 4 [Source:HGNC Symbol;Acc:HGNC:7662]",{"v":24.8637538351336,"d":"24.86"},{"v":66.5392681392837,"d":"66.54"},{"v":0.373670383375534,"d":"0.37"},{"v":-1.42016187275413,"d":"-1.42"},{"v":0.036460481046189,"d":"0.04"},{"v":0.593661117938102,"d":"0.59"},"down","yes"]
["ENSG00000168229","PTGDR","ENST00000306051;ENST00000553372","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0004930(G-protein coupled receptor activity);GO:0007186(G-protein coupled receptor signaling pathway);GO:0005886(plasma membrane);GO:0004871(signal transducer activity);GO:0007165(signal transduction);GO:0005515(protein binding);GO:0097755(positive regulation of blood vessel diameter);GO:0004957(prostaglandin E receptor activity);GO:0071380(cellular response to prostaglandin E stimulus);GO:0001785(prostaglandin J receptor activity);GO:0004956(prostaglandin D receptor activity);GO:0006954(inflammatory response);GO:0030238(male sex determination);GO:0030431(sleep);GO:0046085(adenosine metabolic process);GO:0071799(cellular response to prostaglandin D stimulus);GO:0071799(cellular response to prostaglandin D stimulus)","04080(Neuroactive ligand-receptor interaction);04080(Neuroactive ligand-receptor interaction)","K04332","NA","prostaglandin D2 receptor [Source:HGNC Symbol;Acc:HGNC:9591]",{"v":3.89625374678536,"d":"3.90"},{"v":1.49702935575338,"d":"1.50"},{"v":2.60265687630726,"d":"2.60"},{"v":1.37998512523438,"d":"1.38"},{"v":0.0364814173122568,"d":"0.04"},{"v":0.593661117938102,"d":"0.59"},"up","yes"]
["MSTRG.2058","NLRP6","ENST00000534750;ENST00000312165","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0005886(plasma membrane);GO:0002376(immune system process);GO:0045087(innate immune response);GO:0006954(inflammatory response);GO:0007186(G-protein coupled receptor signaling pathway);GO:0005000(vasopressin receptor activity);GO:0031965(nuclear membrane);GO:0050727(regulation of inflammatory response);GO:0061702(inflammasome complex);GO:0002862(negative regulation of inflammatory response to antigenic stimulus);GO:0009617(response to bacterium);GO:0010506(regulation of autophagy);GO:0034122(negative regulation of toll-like receptor signaling pathway);GO:0042060(wound healing);GO:0043124(negative regulation of I-kappaB kinase/NF-kappaB signaling);GO:0043409(negative regulation of MAPK cascade);GO:0050777(negative regulation of immune response);GO:0070255(regulation of mucus secretion);GO:0070373(negative regulation of ERK1 and ERK2 cascade);GO:0070373(negative regulation of ERK1 and ERK2 cascade)","04621(NOD-like receptor signaling pathway);04621(NOD-like receptor signaling pathway)","K20863","NA","NLR family pyrin domain containing 6 [Source:HGNC Symbol;Acc:HGNC:22944]",{"v":1.88500436856876,"d":"1.89"},{"v":5.08972543529779,"d":"5.09"},{"v":0.370354824151427,"d":"0.37"},{"v":-1.4330199653701,"d":"-1.43"},{"v":0.0365673940543141,"d":"0.04"},{"v":0.594257164915048,"d":"0.59"},"down","yes"]
["MSTRG.11529","TADA2B","ENST00000310074;ENST00000506692;ENST00000515646;ENST00000510704;ENST00000512388","GO:0005634(nucleus);GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0003713(transcription coactivator activity);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0035065(regulation of histone acetylation);GO:0016573(histone acetylation);GO:0003682(chromatin binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0005654(nucleoplasm);GO:0016579(protein deubiquitination);GO:0006338(chromatin remodeling);GO:0036459(thiol-dependent ubiquitinyl hydrolase activity);GO:0035066(positive regulation of histone acetylation);GO:0070461(SAGA-type complex);GO:0004402(histone acetyltransferase activity);GO:0030914(STAGA complex);GO:0030914(STAGA complex)","NA","NA","NA","transcriptional adaptor 2B [Source:HGNC Symbol;Acc:HGNC:30781]",{"v":3.83413766637812,"d":"3.83"},{"v":1.47720966707064,"d":"1.48"},{"v":2.59552706149111,"d":"2.60"},{"v":1.37602752963901,"d":"1.38"},{"v":0.0366749009185508,"d":"0.04"},{"v":0.595201020028556,"d":"0.60"},"up","yes"]
["ENSG00000183307","TMEM121B","ENST00000331437","NA","NA","NA","NA","transmembrane protein 121B [Source:HGNC Symbol;Acc:HGNC:1844]",{"v":1.68412935411324,"d":"1.68"},{"v":0.643810855000986,"d":"0.64"},{"v":2.61587598443127,"d":"2.62"},{"v":1.3872941460015,"d":"1.39"},{"v":0.0367693695203909,"d":"0.04"},{"v":0.59593101987153,"d":"0.60"},"up","yes"]
["MSTRG.4476","PLEKHG3","ENST00000484731;ENST00000490180;ENST00000247226;ENST00000554088;ENST00000471182;MSTRG.4476.1;MSTRG.4476.3;ENST00000555982;ENST00000554499;ENST00000492928","GO:0005089(Rho guanyl-nucleotide exchange factor activity);GO:0035023(regulation of Rho protein signal transduction);GO:0043547(positive regulation of GTPase activity);GO:0043547(positive regulation of GTPase activity)","NA","NA","NA","pleckstrin homology and RhoGEF domain containing G3 [Source:HGNC Symbol;Acc:HGNC:20364]",{"v":3.6311723424152,"d":"3.63"},{"v":9.68825157663317,"d":"9.69"},{"v":0.374801615512661,"d":"0.37"},{"v":-1.41580092340819,"d":"-1.42"},{"v":0.0370023989668387,"d":"0.04"},{"v":0.59870854194979,"d":"0.60"},"down","yes"]
["ENSG00000109586","GALNT7","ENST00000265000;ENST00000506317;ENST00000512285;ENST00000515862;ENST00000502407;ENST00000505308","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0046872(metal ion binding);GO:0016740(transferase activity);GO:0030246(carbohydrate binding);GO:0016757(transferase activity, transferring glycosyl groups);GO:0005794(Golgi apparatus);GO:0000139(Golgi membrane);GO:0006486(protein glycosylation);GO:0070062(extracellular exosome);GO:0005975(carbohydrate metabolic process);GO:0006493(protein O-linked glycosylation);GO:0016266(O-glycan processing);GO:0004653(polypeptide N-acetylgalactosaminyltransferase activity);GO:0004653(polypeptide N-acetylgalactosaminyltransferase activity)","00512(Mucin type O-glycan biosynthesis);00512(Mucin type O-glycan biosynthesis)","K00710","EC:2.4.1.41","polypeptide N-acetylgalactosaminyltransferase 7 [Source:HGNC Symbol;Acc:HGNC:4129]",{"v":0.983938980626366,"d":"0.98"},{"v":2.64554735469774,"d":"2.65"},{"v":0.371922649155824,"d":"0.37"},{"v":-1.42692548775534,"d":"-1.43"},{"v":0.0370401813446764,"d":"0.04"},{"v":0.59870854194979,"d":"0.60"},"down","yes"]
["MSTRG.9560","AL117335.1","ENST00000619200;ENST00000615777;ENST00000620919","NA","NA","NA","NA",null,{"v":0.532323373366521,"d":"0.53"},{"v":1.4954538170504,"d":"1.50"},{"v":0.355961091741679,"d":"0.36"},{"v":-1.49020853858054,"d":"-1.49"},{"v":0.037125053998487,"d":"0.04"},{"v":0.599276005696757,"d":"0.60"},"down","yes"]
["MSTRG.10422","CSF2RB","MSTRG.10422.1;ENST00000403662;ENST00000406230;MSTRG.10422.2;ENST00000421539","GO:0005622(intracellular);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0018108(peptidyl-tyrosine phosphorylation);GO:0043547(positive regulation of GTPase activity);GO:0005515(protein binding);GO:0007165(signal transduction);GO:0004896(cytokine receptor activity);GO:0005886(plasma membrane);GO:0019221(cytokine-mediated signaling pathway);GO:0005887(integral component of plasma membrane);GO:0044267(cellular protein metabolic process);GO:0000165(MAPK cascade);GO:0004872(receptor activity);GO:0005088(Ras guanyl-nucleotide exchange factor activity);GO:0004713(protein tyrosine kinase activity);GO:0007585(respiratory gaseous exchange);GO:0036016(cellular response to interleukin-3);GO:0038156(interleukin-3-mediated signaling pathway);GO:0004912(interleukin-3 receptor activity);GO:0004914(interleukin-5 receptor activity);GO:0032496(response to lipopolysaccharide);GO:0038043(interleukin-5-mediated signaling pathway);GO:0030526(granulocyte macrophage colony-stimulating factor receptor complex);GO:0030526(granulocyte macrophage colony-stimulating factor receptor complex)","04630(Jak-STAT signaling pathway);04060(Cytokine-cytokine receptor interaction);04210(Apoptosis);05200(Pathways in cancer);05200(Pathways in cancer)","K04738","NA","colony stimulating factor 2 receptor beta common subunit [Source:HGNC Symbol;Acc:HGNC:2436]",{"v":30.5999396296429,"d":"30.60"},{"v":81.4959181369101,"d":"81.50"},{"v":0.375478187487085,"d":"0.38"},{"v":-1.41319899465313,"d":"-1.41"},{"v":0.0371927346633225,"d":"0.04"},{"v":0.599564806982234,"d":"0.60"},"down","yes"]
["MSTRG.4487","ATP6V1D","ENST00000216442;ENST00000553974;ENST00000555625;ENST00000554087;ENST00000553408;ENST00000554236;ENST00000553687;ENST00000555335;ENST00000555431;ENST00000557244;ENST00000555474","GO:0006810(transport);GO:0016020(membrane);GO:0005765(lysosomal membrane);GO:0055085(transmembrane transport);GO:0006811(ion transport);GO:0005515(protein binding);GO:0015992(proton transport);GO:0042626(ATPase activity, coupled to transmembrane movement of substances);GO:0005813(centrosome);GO:0005886(plasma membrane);GO:0060271(cilium assembly);GO:0005929(cilium);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0034220(ion transmembrane transport);GO:0030030(cell projection organization);GO:0043312(neutrophil degranulation);GO:0035579(specific granule membrane);GO:0008286(insulin receptor signaling pathway);GO:0016241(regulation of macroautophagy);GO:0033572(transferrin transport);GO:0090383(phagosome acidification);GO:0061512(protein localization to cilium);GO:0033176(proton-transporting V-type ATPase complex);GO:0033176(proton-transporting V-type ATPase complex)","00190(Oxidative phosphorylation);04150(mTOR signaling pathway);04145(Phagosome);04966(Collecting duct acid secretion);04721(Synaptic vesicle cycle);05323(Rheumatoid arthritis);05110(Vibrio cholerae infection);05120(Epithelial cell signaling in Helicobacter pylori infection);05120(Epithelial cell signaling in Helicobacter pylori infection)","K02149","NA","ATPase H+ transporting V1 subunit D [Source:HGNC Symbol;Acc:HGNC:13527]",{"v":0.981004218772054,"d":"0.98"},{"v":2.64953837026582,"d":"2.65"},{"v":0.370254769578458,"d":"0.37"},{"v":-1.43340977462545,"d":"-1.43"},{"v":0.0373499703945375,"d":"0.04"},{"v":0.599793418536231,"d":"0.60"},"down","yes"]
["MSTRG.8142","BLVRB","ENST00000263368;ENST00000601346;ENST00000597870;ENST00000595483","GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0005886(plasma membrane);GO:0004074(biliverdin reductase activity);GO:0042167(heme catabolic process);GO:0070062(extracellular exosome);GO:0042602(riboflavin reductase (NADPH) activity);GO:0043195(terminal bouton);GO:0043195(terminal bouton)","00740(Riboflavin metabolism);00860(Porphyrin and chlorophyll metabolism);00860(Porphyrin and chlorophyll metabolism)","K05901","EC:1.3.1.24;EC:1.5.1.30","biliverdin reductase B [Source:HGNC Symbol;Acc:HGNC:1063]",{"v":18.7831719927928,"d":"18.78"},{"v":50.0376414612613,"d":"50.04"},{"v":0.375380842187267,"d":"0.38"},{"v":-1.4135730717476,"d":"-1.41"},{"v":0.0373960092391171,"d":"0.04"},{"v":0.599793418536231,"d":"0.60"},"down","yes"]
["MSTRG.8552","CENPO","ENST00000498362;ENST00000473706;ENST00000491031;ENST00000486527;ENST00000380834","GO:0005634(nucleus);GO:0005694(chromosome);GO:0005515(protein binding);GO:0034508(centromere complex assembly);GO:0000776(kinetochore);GO:0000775(chromosome, centromeric region);GO:0000777(condensed chromosome kinetochore);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0034080(CENP-A containing nucleosome assembly);GO:0007062(sister chromatid cohesion);GO:0007062(sister chromatid cohesion)","NA","NA","NA","centromere protein O [Source:HGNC Symbol;Acc:HGNC:28152]",{"v":0.2454473338166,"d":"0.25"},{"v":0.685184926060167,"d":"0.69"},{"v":0.358220568610476,"d":"0.36"},{"v":-1.48107991730557,"d":"-1.48"},{"v":0.0374299492942513,"d":"0.04"},{"v":0.599793418536231,"d":"0.60"},"down","yes"]
["MSTRG.14171","WDR60","ENST00000407559;ENST00000467220","GO:0042995(cell projection);GO:0005515(protein binding);GO:0005615(extracellular space);GO:0005813(centrosome);GO:0005929(cilium);GO:0035735(intraciliary transport involved in cilium assembly);GO:0097542(ciliary tip);GO:0070062(extracellular exosome);GO:0030030(cell projection organization);GO:0060271(cilium assembly);GO:0007018(microtubule-based movement);GO:0008574(ATP-dependent microtubule motor activity, plus-end-directed);GO:0045503(dynein light chain binding);GO:0045504(dynein heavy chain binding);GO:0005868(cytoplasmic dynein complex);GO:0000922(spindle pole);GO:0031021(interphase microtubule organizing center);GO:0000242(pericentriolar material);GO:0097546(ciliary base);GO:0048704(embryonic skeletal system morphogenesis);GO:0048704(embryonic skeletal system morphogenesis)","NA","NA","NA","WD repeat domain 60 [Source:HGNC Symbol;Acc:HGNC:21862]",{"v":1.48742342822859,"d":"1.49"},{"v":0.570827501724914,"d":"0.57"},{"v":2.60573189577224,"d":"2.61"},{"v":1.38168865238735,"d":"1.38"},{"v":0.0374316759119806,"d":"0.04"},{"v":0.599793418536231,"d":"0.60"},"up","yes"]
["MSTRG.13701","NCF1B","ENST00000423083;MSTRG.13701.1;ENST00000435988;MSTRG.13701.2;MSTRG.13701.3;ENST00000432102","NA","NA","NA","NA","neutrophil cytosolic factor 1B pseudogene [Source:HGNC Symbol;Acc:HGNC:32522]",{"v":17.2776397723031,"d":"17.28"},{"v":45.9940410656962,"d":"45.99"},{"v":0.375649527025128,"d":"0.38"},{"v":-1.41254080909732,"d":"-1.41"},{"v":0.0374960068439515,"d":"0.04"},{"v":0.599793418536231,"d":"0.60"},"down","yes"]
["MSTRG.13297","IFNGR1","ENST00000367739;ENST00000478333;ENST00000458076;ENST00000414770","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0043231(intracellular membrane-bounded organelle);GO:0005783(endoplasmic reticulum);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0019955(cytokine binding);GO:0051607(defense response to virus);GO:0014069(postsynaptic density);GO:0030425(dendrite);GO:0031982(vesicle);GO:0005887(integral component of plasma membrane);GO:0007165(signal transduction);GO:0009615(response to virus);GO:0060333(interferon-gamma-mediated signaling pathway);GO:0060334(regulation of interferon-gamma-mediated signaling pathway);GO:0004906(interferon-gamma receptor activity);GO:0004906(interferon-gamma receptor activity)","04630(Jak-STAT signaling pathway);04066(HIF-1 signaling pathway);04060(Cytokine-cytokine receptor interaction);04217(Necroptosis);04650(Natural killer cell mediated cytotoxicity);04658(Th1 and Th2 cell differentiation);04659(Th17 cell differentiation);04380(Osteoclast differentiation);05200(Pathways in cancer);05321(Inflammatiory bowel disease (IBD));05132(Salmonella infection);05152(Tuberculosis);05162(Measles);05164(Influenza A);05168(Herpes simplex infection);05167(Kaposi's sarcoma-associated herpesvirus infection);05145(Toxoplasmosis);05140(Leishmaniasis);05142(Chagas disease (American trypanosomiasis));05142(Chagas disease (American trypanosomiasis))","K05132","NA","interferon gamma receptor 1 [Source:HGNC Symbol;Acc:HGNC:5439]",{"v":19.2108815904317,"d":"19.21"},{"v":51.1052061793077,"d":"51.11"},{"v":0.375908503783908,"d":"0.38"},{"v":-1.41154654256016,"d":"-1.41"},{"v":0.037558146278277,"d":"0.04"},{"v":0.599793418536231,"d":"0.60"},"down","yes"]
["ENSG00000092758","COL9A3","ENST00000466192;ENST00000462700;ENST00000343916;ENST00000463487;ENST00000466532;ENST00000469802;ENST00000467819;ENST00000472880","GO:0005576(extracellular region);GO:0005581(collagen trimer);GO:0005578(proteinaceous extracellular matrix);GO:0005788(endoplasmic reticulum lumen);GO:0030198(extracellular matrix organization);GO:0030020(extracellular matrix structural constituent conferring tensile strength);GO:0005594(collagen type IX trimer);GO:0008584(male gonad development);GO:0008585(female gonad development);GO:0008585(female gonad development)","04151(PI3K-Akt signaling pathway);04512(ECM-receptor interaction);04510(Focal adhesion);04974(Protein digestion and absorption);05165(Human papillomavirus infection);05165(Human papillomavirus infection)","K08131","NA","collagen type IX alpha 3 chain [Source:HGNC Symbol;Acc:HGNC:2219]",{"v":0.42043332001656,"d":"0.42"},{"v":1.16036440426413,"d":"1.16"},{"v":0.362328694737225,"d":"0.36"},{"v":-1.46462902987508,"d":"-1.46"},{"v":0.0376201775946158,"d":"0.04"},{"v":0.599793418536231,"d":"0.60"},"down","yes"]
["ENSG00000248905","FMN1","ENST00000616417;ENST00000558628;ENST00000561249;ENST00000558197;ENST00000334528;ENST00000560317;ENST00000559610","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0003779(actin binding);GO:0005886(plasma membrane);GO:0008017(microtubule binding);GO:0030054(cell junction);GO:0045010(actin nucleation);GO:0005884(actin filament);GO:0005912(adherens junction);GO:0017124(SH3 domain binding);GO:0001822(kidney development);GO:0010467(gene expression);GO:0030838(positive regulation of actin filament polymerization);GO:0035136(forelimb morphogenesis);GO:0035137(hindlimb morphogenesis);GO:0048705(skeletal system morphogenesis);GO:0048813(dendrite morphogenesis);GO:0051127(positive regulation of actin nucleation);GO:0051894(positive regulation of focal adhesion assembly);GO:0060173(limb development);GO:0072092(ureteric bud invasion);GO:0015630(microtubule cytoskeleton);GO:0015630(microtubule cytoskeleton)","NA","NA","NA","formin 1 [Source:HGNC Symbol;Acc:HGNC:3768]",{"v":0.799294561392153,"d":"0.80"},{"v":0.309144476598287,"d":"0.31"},{"v":2.58550490756716,"d":"2.59"},{"v":1.37044604321468,"d":"1.37"},{"v":0.0376232470862717,"d":"0.04"},{"v":0.599793418536231,"d":"0.60"},"up","yes"]
["ENSG00000157456","CCNB2","ENST00000288207;ENST00000561077;ENST00000621385","GO:0005634(nucleus);GO:0005829(cytosol);GO:0051301(cell division);GO:0005515(protein binding);GO:0007049(cell cycle);GO:0005813(centrosome);GO:0045296(cadherin binding);GO:0000086(G2/M transition of mitotic cell cycle);GO:0007077(mitotic nuclear envelope disassembly);GO:0015630(microtubule cytoskeleton);GO:0004693(cyclin-dependent protein serine/threonine kinase activity);GO:0001701(in utero embryonic development);GO:0040007(growth);GO:0043029(T cell homeostasis);GO:0048538(thymus development);GO:0051726(regulation of cell cycle);GO:0016020(membrane);GO:0016020(membrane)","04068(FoxO signaling pathway);04110(Cell cycle);04114(Oocyte meiosis);04115(p53 signaling pathway);04218(Cellular senescence);04914(Progesterone-mediated oocyte maturation);05166(HTLV-I infection);05166(HTLV-I infection)","K21770","NA","cyclin B2 [Source:HGNC Symbol;Acc:HGNC:1580]",{"v":0.796096365226705,"d":"0.80"},{"v":0.290401274901821,"d":"0.29"},{"v":2.74136663310397,"d":"2.74"},{"v":1.45489528853905,"d":"1.45"},{"v":0.0376551921950997,"d":"0.04"},{"v":0.599793418536231,"d":"0.60"},"up","yes"]
["MSTRG.6991","UBE2Z","ENST00000360943;ENST00000504684;ENST00000513342;ENST00000514948;ENST00000506271;ENST00000511373","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0016740(transferase activity);GO:0016567(protein ubiquitination);GO:0005515(protein binding);GO:0006915(apoptotic process);GO:0031625(ubiquitin protein ligase binding);GO:0061630(ubiquitin protein ligase activity);GO:0043065(positive regulation of apoptotic process);GO:0061631(ubiquitin conjugating enzyme activity);GO:0042787(protein ubiquitination involved in ubiquitin-dependent protein catabolic process);GO:0042787(protein ubiquitination involved in ubiquitin-dependent protein catabolic process)","04120(Ubiquitin mediated proteolysis);04120(Ubiquitin mediated proteolysis)","K10585","EC:2.3.2.23","ubiquitin conjugating enzyme E2 Z [Source:HGNC Symbol;Acc:HGNC:25847]",{"v":10.8837257116287,"d":"10.88"},{"v":4.2393612332696,"d":"4.24"},{"v":2.56730321214799,"d":"2.57"},{"v":1.36025369592466,"d":"1.36"},{"v":0.0377526464373747,"d":"0.04"},{"v":0.600551345308938,"d":"0.60"},"up","yes"]
["ENSG00000149527","PLCH2","ENST00000473964;ENST00000449969;ENST00000378486;ENST00000609981;ENST00000343889;ENST00000278878","GO:0005622(intracellular);GO:0035556(intracellular signal transduction);GO:0004629(phospholipase C activity);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0046872(metal ion binding);GO:0016787(hydrolase activity);GO:0005509(calcium ion binding);GO:0007165(signal transduction);GO:0006629(lipid metabolic process);GO:0016042(lipid catabolic process);GO:0005886(plasma membrane);GO:0004871(signal transducer activity);GO:0008081(phosphoric diester hydrolase activity);GO:0004435(phosphatidylinositol phospholipase C activity);GO:0003674(molecular_function);GO:0008150(biological_process);GO:0005575(cellular_component);GO:0043647(inositol phosphate metabolic process);GO:0046488(phosphatidylinositol metabolic process);GO:0046488(phosphatidylinositol metabolic process)","00562(Inositol phosphate metabolism);00562(Inositol phosphate metabolism)","K19006","EC:3.1.4.11","phospholipase C eta 2 [Source:HGNC Symbol;Acc:HGNC:29037]",{"v":0.631539027084686,"d":"0.63"},{"v":0.240977098877655,"d":"0.24"},{"v":2.62074292547327,"d":"2.62"},{"v":1.38997584342806,"d":"1.39"},{"v":0.0378077857643875,"d":"0.04"},{"v":0.600588460206967,"d":"0.60"},"up","yes"]
["MSTRG.14561","PVT1","MSTRG.14561.24;ENST00000518528;ENST00000521600;ENST00000522414;ENST00000615442;ENST00000512617;ENST00000612011;ENST00000616386;ENST00000520913;ENST00000504719;ENST00000523190;ENST00000517838;ENST00000521951;ENST00000513868;ENST00000519481","NA","NA","NA","NA","Pvt1 oncogene (non-protein coding) [Source:HGNC Symbol;Acc:HGNC:9709]",{"v":0.756369394866193,"d":"0.76"},{"v":0.287438572000728,"d":"0.29"},{"v":2.63141230351046,"d":"2.63"},{"v":1.39583731525676,"d":"1.40"},{"v":0.0378547285581372,"d":"0.04"},{"v":0.600588460206967,"d":"0.60"},"up","yes"]
["ENSG00000136404","TM6SF1","ENST00000322019;ENST00000379384;ENST00000564988;ENST00000561551;ENST00000565982;ENST00000379390;ENST00000565774","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005765(lysosomal membrane);GO:0005764(lysosome);GO:0003674(molecular_function);GO:0008150(biological_process);GO:0005515(protein binding);GO:0005515(protein binding)","NA","NA","NA","transmembrane 6 superfamily member 1 [Source:HGNC Symbol;Acc:HGNC:11860]",{"v":2.0097864998121,"d":"2.01"},{"v":5.39041563885757,"d":"5.39"},{"v":0.372844439921158,"d":"0.37"},{"v":-1.4233542675324,"d":"-1.42"},{"v":0.0379974982359055,"d":"0.04"},{"v":0.602060360206282,"d":"0.60"},"down","yes"]
["MSTRG.15354","TAF1","MSTRG.15354.1","NA","NA","NA","NA",null,{"v":14.318986,"d":"14.32"},{"v":5.577873,"d":"5.58"},{"v":2.56710505958096,"d":"2.57"},{"v":1.36014233986927,"d":"1.36"},{"v":0.0380660806695685,"d":"0.04"},{"v":0.602354459162869,"d":"0.60"},"up","yes"]
["ENSG00000254685","FPGT","ENST00000370898;ENST00000482102;ENST00000534056;ENST00000472069;ENST00000467578;ENST00000370894;ENST00000524915","GO:0016772(transferase activity, transferring phosphorus-containing groups);GO:0005737(cytoplasm);GO:0000166(nucleotide binding);GO:0016740(transferase activity);GO:0005525(GTP binding);GO:0016779(nucleotidyltransferase activity);GO:0005829(cytosol);GO:0003824(catalytic activity);GO:0047341(fucose-1-phosphate guanylyltransferase activity);GO:0006004(fucose metabolic process);GO:0006004(fucose metabolic process)","00051(Fructose and mannose metabolism);00520(Amino sugar and nucleotide sugar metabolism);00520(Amino sugar and nucleotide sugar metabolism)","K00976","EC:2.7.7.30","fucose-1-phosphate guanylyltransferase [Source:HGNC Symbol;Acc:HGNC:3825]",{"v":0.152689668421053,"d":"0.15"},{"v":0.432042820813397,"d":"0.43"},{"v":0.353413275410034,"d":"0.35"},{"v":-1.50057186142539,"d":"-1.50"},{"v":0.0382203831386973,"d":"0.04"},{"v":0.604002432750909,"d":"0.60"},"down","yes"]
["MSTRG.378","S100PBP","ENST00000373475;ENST00000356689;ENST00000530710;ENST00000525203;ENST00000482212;ENST00000524535;ENST00000477248;ENST00000475486;ENST00000474103;ENST00000531123;ENST00000373476;ENST00000530552;ENST00000529027","GO:0048306(calcium-dependent protein binding);GO:0005634(nucleus);GO:0016607(nuclear speck);GO:0005829(cytosol);GO:0005829(cytosol)","NA","NA","NA","S100P binding protein [Source:HGNC Symbol;Acc:HGNC:25768]",{"v":0.547756400369806,"d":"0.55"},{"v":1.47340802469002,"d":"1.47"},{"v":0.371761515609394,"d":"0.37"},{"v":-1.4275506632882,"d":"-1.43"},{"v":0.0384381270243716,"d":"0.04"},{"v":0.60664734682501,"d":"0.61"},"down","yes"]
["MSTRG.9186","AC009506.1","ENST00000418474","NA","NA","NA","NA",null,{"v":4.888749,"d":"4.89"},{"v":1.890819,"d":"1.89"},{"v":2.58551929084698,"d":"2.59"},{"v":1.37045406896961,"d":"1.37"},{"v":0.0386630424972933,"d":"0.04"},{"v":0.609398374021473,"d":"0.61"},"up","yes"]
["MSTRG.5445","SLCO3A1","ENST00000318445;ENST00000424469;ENST00000566477;ENST00000555769;ENST00000555892;ENST00000555549;ENST00000555111;ENST00000556649;ENST00000555513;ENST00000553653;ENST00000555210;ENST00000564072;ENST00000553304","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005215(transporter activity);GO:0006811(ion transport);GO:0005886(plasma membrane);GO:0015347(sodium-independent organic anion transmembrane transporter activity);GO:0043252(sodium-independent organic anion transport);GO:0005887(integral component of plasma membrane);GO:0015732(prostaglandin transport);GO:0015732(prostaglandin transport)","NA","NA","NA","solute carrier organic anion transporter family member 3A1 [Source:HGNC Symbol;Acc:HGNC:10952]",{"v":2.71408357509274,"d":"2.71"},{"v":7.18923142140965,"d":"7.19"},{"v":0.377520685592365,"d":"0.38"},{"v":-1.40537239830684,"d":"-1.41"},{"v":0.0388489521372894,"d":"0.04"},{"v":0.60966617140794,"d":"0.61"},"down","yes"]
["MSTRG.15210","TAB3","ENST00000467136;ENST00000378932;ENST00000378933;ENST00000378928;ENST00000288422;ENST00000378930","GO:0046872(metal ion binding);GO:0005515(protein binding);GO:0038095(Fc-epsilon receptor signaling pathway);GO:0005886(plasma membrane);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0010008(endosome membrane);GO:0002223(stimulatory C-type lectin receptor signaling pathway);GO:0010507(negative regulation of autophagy);GO:0002755(MyD88-dependent toll-like receptor signaling pathway);GO:0007249(I-kappaB kinase/NF-kappaB signaling);GO:0007254(JNK cascade);GO:0051092(positive regulation of NF-kappaB transcription factor activity);GO:0070423(nucleotide-binding oligomerization domain containing signaling pathway);GO:0000187(activation of MAPK activity);GO:0000187(activation of MAPK activity)","04064(NF-kappa B signaling pathway);04668(TNF signaling pathway);04621(NOD-like receptor signaling pathway);04657(IL-17 signaling pathway);04657(IL-17 signaling pathway)","K12793","NA","TGF-beta activated kinase 1 and MAP3K7 binding protein 3 [Source:HGNC Symbol;Acc:HGNC:30681]",{"v":0.685234011092754,"d":"0.69"},{"v":1.81895916717803,"d":"1.82"},{"v":0.376717643505896,"d":"0.38"},{"v":-1.40844449164618,"d":"-1.41"},{"v":0.0388511638926841,"d":"0.04"},{"v":0.60966617140794,"d":"0.61"},"down","yes"]
["MSTRG.4628","ITPK1","ENST00000555495;ENST00000554999;ENST00000354313;ENST00000553655;ENST00000556603;ENST00000555553;ENST00000556954;ENST00000267615;ENST00000553695;ENST00000556185","GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0016853(isomerase activity);GO:0016740(transferase activity);GO:0000287(magnesium ion binding);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0016787(hydrolase activity);GO:0005622(intracellular);GO:0016311(dephosphorylation);GO:0047325(inositol tetrakisphosphate 1-kinase activity);GO:0052725(inositol-1,3,4-trisphosphate 6-kinase activity);GO:0052726(inositol-1,3,4-trisphosphate 5-kinase activity);GO:0021915(neural tube development);GO:0032957(inositol trisphosphate metabolic process);GO:0016324(apical plasma membrane);GO:0005829(cytosol);GO:0007165(signal transduction);GO:0043647(inositol phosphate metabolic process);GO:0003824(catalytic activity);GO:0007596(blood coagulation);GO:0052659(inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity);GO:0052825(inositol-1,3,4,5,6-pentakisphosphate 1-phosphatase activity);GO:0052830(inositol-1,3,4,6-tetrakisphosphate 6-phosphatase activity);GO:0052831(inositol-1,3,4,6-tetrakisphosphate 1-phosphatase activity);GO:0052835(inositol-3,4,6-trisphosphate 1-kinase activity);GO:0052835(inositol-3,4,6-trisphosphate 1-kinase activity)","00562(Inositol phosphate metabolism);04070(Phosphatidylinositol signaling system);04070(Phosphatidylinositol signaling system)","K00913","EC:2.7.1.159;EC:2.7.1.134","inositol-tetrakisphosphate 1-kinase [Source:HGNC Symbol;Acc:HGNC:6177]",{"v":7.54548982795223,"d":"7.55"},{"v":19.9417807228365,"d":"19.94"},{"v":0.378375930054804,"d":"0.38"},{"v":-1.40210777866,"d":"-1.40"},{"v":0.0388704345470882,"d":"0.04"},{"v":0.60966617140794,"d":"0.61"},"down","yes"]
["ENSG00000135525","MAP7","ENST00000617204","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0015630(microtubule cytoskeleton);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0048471(perinuclear region of cytoplasm);GO:0005874(microtubule);GO:0000226(microtubule cytoskeleton organization);GO:0016323(basolateral plasma membrane);GO:0005875(microtubule associated complex);GO:0005198(structural molecule activity);GO:0005102(receptor binding);GO:0072659(protein localization to plasma membrane);GO:0007163(establishment or maintenance of cell polarity);GO:0006970(response to osmotic stress)","NA","NA","NA","microtubule associated protein 7 [Source:HGNC Symbol;Acc:HGNC:6869]",{"v":0.201311960345144,"d":"0.20"},{"v":0.555777834404259,"d":"0.56"},{"v":0.362216605059342,"d":"0.36"},{"v":-1.46507540975982,"d":"-1.47"},{"v":0.0389108523817209,"d":"0.04"},{"v":0.60966617140794,"d":"0.61"},"down","yes"]
["MSTRG.1107",null,"MSTRG.1107.1","NA","NA","NA","NA",null,{"v":5.896214,"d":"5.90"},{"v":2.154296,"d":"2.15"},{"v":2.73695629569938,"d":"2.74"},{"v":1.45257239762535,"d":"1.45"},{"v":0.0389779837910239,"d":"0.04"},{"v":0.60966617140794,"d":"0.61"},"up","yes"]
["ENSG00000131089","ARHGEF9","ENST00000623951;ENST00000624538;ENST00000637417;ENST00000253401;ENST00000637723;ENST00000636926;ENST00000624783;ENST00000624210;ENST00000637040;ENST00000466925;ENST00000637178;ENST00000637855;ENST00000374872;ENST00000495564;ENST00000636102;ENST00000637557;ENST00000635967;ENST00000374870;ENST00000637520;ENST00000624843;ENST00000639092","GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005089(Rho guanyl-nucleotide exchange factor activity);GO:0035023(regulation of Rho protein signal transduction);GO:0043547(positive regulation of GTPase activity);GO:0005085(guanyl-nucleotide exchange factor activity);GO:0051056(regulation of small GTPase mediated signal transduction);GO:0034220(ion transmembrane transport);GO:0043065(positive regulation of apoptotic process);GO:0043065(positive regulation of apoptotic process)","NA","NA","NA","Cdc42 guanine nucleotide exchange factor 9 [Source:HGNC Symbol;Acc:HGNC:14561]",{"v":0.986631307167235,"d":"0.99"},{"v":0.384067592549561,"d":"0.38"},{"v":2.56890017878798,"d":"2.57"},{"v":1.36115083170798,"d":"1.36"},{"v":0.0389838026892637,"d":"0.04"},{"v":0.60966617140794,"d":"0.61"},"up","yes"]
["MSTRG.12914","RNF5","ENST00000375094;ENST00000487940","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0046872(metal ion binding);GO:0005783(endoplasmic reticulum);GO:0016740(transferase activity);GO:0016567(protein ubiquitination);GO:0005789(endoplasmic reticulum membrane);GO:0005739(mitochondrion);GO:0005515(protein binding);GO:0044322(endoplasmic reticulum quality control compartment);GO:0009617(response to bacterium);GO:0010507(negative regulation of autophagy);GO:0031648(protein destabilization);GO:2000785(regulation of autophagosome assembly);GO:0042802(identical protein binding);GO:0031966(mitochondrial membrane);GO:1904264(ubiquitin protein ligase activity involved in ERAD pathway);GO:0044257(cellular protein catabolic process);GO:0055085(transmembrane transport);GO:0042787(protein ubiquitination involved in ubiquitin-dependent protein catabolic process);GO:0004842(ubiquitin-protein transferase activity);GO:1904380(endoplasmic reticulum mannose trimming);GO:0070534(protein K63-linked ubiquitination);GO:0070936(protein K48-linked ubiquitination);GO:0071712(ER-associated misfolded protein catabolic process);GO:0008270(zinc ion binding);GO:0030433(ubiquitin-dependent ERAD pathway);GO:0036503(ERAD pathway);GO:0036513(Derlin-1 retrotranslocation complex);GO:0044390(ubiquitin-like protein conjugating enzyme binding);GO:0044390(ubiquitin-like protein conjugating enzyme binding)","04141(Protein processing in endoplasmic reticulum);04141(Protein processing in endoplasmic reticulum)","K10666","EC:2.3.2.27","ring finger protein 5 [Source:HGNC Symbol;Acc:HGNC:10068]",{"v":20.0988485169779,"d":"20.10"},{"v":7.86238406791171,"d":"7.86"},{"v":2.55633003213442,"d":"2.56"},{"v":1.35407410584158,"d":"1.35"},{"v":0.0391458549300798,"d":"0.04"},{"v":0.610915576298681,"d":"0.61"},"up","yes"]
["MSTRG.13352","NUP43","ENST00000340413;ENST00000463048;ENST00000403890;ENST00000543637","GO:0006810(transport);GO:0051028(mRNA transport);GO:0005634(nucleus);GO:0015031(protein transport);GO:0051301(cell division);GO:0005694(chromosome);GO:0007049(cell cycle);GO:0005643(nuclear pore);GO:0007059(chromosome segregation);GO:0000775(chromosome, centromeric region);GO:0000776(kinetochore);GO:0000777(condensed chromosome kinetochore);GO:0005515(protein binding);GO:0005829(cytosol);GO:0075733(intracellular transport of virus);GO:0043657(host cell);GO:0007062(sister chromatid cohesion);GO:0016032(viral process);GO:0006406(mRNA export from nucleus);GO:0016925(protein sumoylation);GO:0060964(regulation of gene silencing by miRNA);GO:0006110(regulation of glycolytic process);GO:0006409(tRNA export from nucleus);GO:0007077(mitotic nuclear envelope disassembly);GO:0019083(viral transcription);GO:1900034(regulation of cellular response to heat);GO:0005635(nuclear envelope);GO:0031080(nuclear pore outer ring);GO:0031080(nuclear pore outer ring)","03013(RNA transport);03013(RNA transport)","K14305","NA","nucleoporin 43 [Source:HGNC Symbol;Acc:HGNC:21182]",{"v":2.36304000180505,"d":"2.36"},{"v":0.913252518501805,"d":"0.91"},{"v":2.5874990256601,"d":"2.59"},{"v":1.37155831935569,"d":"1.37"},{"v":0.0391651573577962,"d":"0.04"},{"v":0.610915576298681,"d":"0.61"},"up","yes"]
["MSTRG.10794","TRANK1","MSTRG.10794.1;ENST00000463764;ENST00000429976;ENST00000463984","NA","NA","NA","NA","tetratricopeptide repeat and ankyrin repeat containing 1 [Source:HGNC Symbol;Acc:HGNC:29011]",{"v":4.64402576268934,"d":"4.64"},{"v":12.2419122505093,"d":"12.24"},{"v":0.379354603076503,"d":"0.38"},{"v":-1.39838105144381,"d":"-1.40"},{"v":0.0393702033219494,"d":"0.04"},{"v":0.612671272559718,"d":"0.61"},"down","yes"]
["ENSG00000125945","ZNF436","ENST00000374608","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0005622(intracellular);GO:0005515(protein binding);GO:0003700(transcription factor activity, sequence-specific DNA binding)","NA","NA","NA","zinc finger protein 436 [Source:HGNC Symbol;Acc:HGNC:20814]",{"v":0.560080639344262,"d":"0.56"},{"v":0.212710172131148,"d":"0.21"},{"v":2.63306937196657,"d":"2.63"},{"v":1.3967455317424,"d":"1.40"},{"v":0.0394006500574004,"d":"0.04"},{"v":0.612671272559718,"d":"0.61"},"up","yes"]
["ENSG00000175591","P2RY2","ENST00000393597;ENST00000393596;ENST00000311131","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0004930(G-protein coupled receptor activity);GO:0007186(G-protein coupled receptor signaling pathway);GO:0005886(plasma membrane);GO:0004871(signal transducer activity);GO:0007165(signal transduction);GO:0045028(G-protein coupled purinergic nucleotide receptor activity);GO:0035589(G-protein coupled purinergic nucleotide receptor signaling pathway);GO:0005887(integral component of plasma membrane);GO:0004872(receptor activity);GO:0097746(regulation of blood vessel diameter);GO:0006873(cellular ion homeostasis);GO:0007200(phospholipase C-activating G-protein coupled receptor signaling pathway);GO:0070257(positive regulation of mucus secretion);GO:0070257(positive regulation of mucus secretion)","04080(Neuroactive ligand-receptor interaction);04750(Inflammatory mediator regulation of TRP channels);04750(Inflammatory mediator regulation of TRP channels)","K04269","NA","purinergic receptor P2Y2 [Source:HGNC Symbol;Acc:HGNC:8541]",{"v":0.988642462775253,"d":"0.99"},{"v":0.368807597693114,"d":"0.37"},{"v":2.68064559667208,"d":"2.68"},{"v":1.42258049581397,"d":"1.42"},{"v":0.039430346805662,"d":"0.04"},{"v":0.612671272559718,"d":"0.61"},"up","yes"]
["ENSG00000152217","SETBP1","ENST00000282030;ENST00000426838","GO:0005634(nucleus);GO:0005829(cytosol);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0016604(nuclear body);GO:0016604(nuclear body)","NA","NA","NA","SET binding protein 1 [Source:HGNC Symbol;Acc:HGNC:15573]",{"v":0.80138493310017,"d":"0.80"},{"v":0.310787043583535,"d":"0.31"},{"v":2.57856609419681,"d":"2.58"},{"v":1.36656902538894,"d":"1.37"},{"v":0.0394832141304556,"d":"0.04"},{"v":0.612702145050188,"d":"0.61"},"up","yes"]
["ENSG00000186020","ZNF529","ENST00000586458;ENST00000586115;ENST00000334116;ENST00000587286;ENST00000590656;ENST00000591340;ENST00000585983","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0005622(intracellular);GO:0005622(intracellular)","NA","NA","NA","zinc finger protein 529 [Source:HGNC Symbol;Acc:HGNC:29328]",{"v":0.781060662669766,"d":"0.78"},{"v":0.300485548023981,"d":"0.30"},{"v":2.59932854610176,"d":"2.60"},{"v":1.37813899697864,"d":"1.38"},{"v":0.0399051198532572,"d":"0.04"},{"v":0.618077238133507,"d":"0.62"},"up","yes"]
["ENSG00000109458","GAB1","ENST00000262994;ENST00000510615;ENST00000507070;ENST00000511109;ENST00000515388;ENST00000514639;ENST00000507334;ENST00000262995;ENST00000512843;ENST00000511836","GO:0009967(positive regulation of signal transduction);GO:0005515(protein binding);GO:0036092(phosphatidylinositol-3-phosphate biosynthetic process);GO:0046854(phosphatidylinositol phosphorylation);GO:0005829(cytosol);GO:0046934(phosphatidylinositol-4,5-bisphosphate 3-kinase activity);GO:0007411(axon guidance);GO:0014066(regulation of phosphatidylinositol 3-kinase signaling);GO:0038111(interleukin-7-mediated signaling pathway);GO:0048015(phosphatidylinositol-mediated signaling);GO:0016303(1-phosphatidylinositol-3-kinase activity);GO:0008283(cell proliferation);GO:0005070(SH3/SH2 adaptor activity);GO:0038128(ERBB2 signaling pathway);GO:0007173(epidermal growth factor receptor signaling pathway);GO:0008286(insulin receptor signaling pathway);GO:0035728(response to hepatocyte growth factor);GO:0035728(response to hepatocyte growth factor)","04014(Ras signaling pathway);04012(ErbB signaling pathway);04072(Phospholipase D signaling pathway);04722(Neurotrophin signaling pathway);05205(Proteoglycans in cancer);05225(Hepatocellular carcinoma);05226(Gastric cancer);05211(Renal cell carcinoma);05100(Bacterial invasion of epithelial cells);01521(EGFR tyrosine kinase inhibitor resistance);01521(EGFR tyrosine kinase inhibitor resistance)","K09593","NA","GRB2 associated binding protein 1 [Source:HGNC Symbol;Acc:HGNC:4066]",{"v":0.481650689692657,"d":"0.48"},{"v":1.28229275264354,"d":"1.28"},{"v":0.375616791641144,"d":"0.38"},{"v":-1.41266653595341,"d":"-1.41"},{"v":0.0399322447490341,"d":"0.04"},{"v":0.618077238133507,"d":"0.62"},"down","yes"]
["ENSG00000175606","TMEM70","ENST00000312184;ENST00000416961;ENST00000517614;ENST00000517439;ENST00000519551","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005654(nucleoplasm);GO:0005739(mitochondrion);GO:0005743(mitochondrial inner membrane);GO:0003674(molecular_function);GO:0033615(mitochondrial proton-transporting ATP synthase complex assembly);GO:0032592(integral component of mitochondrial membrane);GO:0032592(integral component of mitochondrial membrane)","NA","NA","NA","transmembrane protein 70 [Source:HGNC Symbol;Acc:HGNC:26050]",{"v":0.466080098591549,"d":"0.47"},{"v":1.25843982997988,"d":"1.26"},{"v":0.370363435333258,"d":"0.37"},{"v":-1.43298642141688,"d":"-1.43"},{"v":0.0400538166859744,"d":"0.04"},{"v":0.618944936372352,"d":"0.62"},"down","yes"]
["MSTRG.8497","KIDINS220","MSTRG.8497.3;ENST00000569008;ENST00000496725;ENST00000489024;ENST00000459813;ENST00000319688;ENST00000638224;ENST00000474782;ENST00000488729;ENST00000471685;ENST00000471275","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0007399(nervous system development);GO:0005768(endosome);GO:0005829(cytosol);GO:0043234(protein complex);GO:0045859(regulation of protein kinase activity);GO:0005770(late endosome);GO:0030165(PDZ domain binding);GO:0010976(positive regulation of neuron projection development);GO:0000186(activation of MAPKK activity);GO:0038180(nerve growth factor signaling pathway);GO:1990090(cellular response to nerve growth factor stimulus);GO:0019887(protein kinase regulator activity);GO:0001701(in utero embryonic development);GO:0048813(dendrite morphogenesis);GO:0048813(dendrite morphogenesis)","04722(Neurotrophin signaling pathway);04722(Neurotrophin signaling pathway)","NA","NA","kinase D interacting substrate 220 [Source:HGNC Symbol;Acc:HGNC:29508]",{"v":1.95482486704617,"d":"1.95"},{"v":5.1414620315623,"d":"5.14"},{"v":0.380207974900122,"d":"0.38"},{"v":-1.39513930191143,"d":"-1.40"},{"v":0.0400911020071777,"d":"0.04"},{"v":0.618944936372352,"d":"0.62"},"down","yes"]
["MSTRG.11342","TNFSF10","ENST00000241261;ENST00000466777;ENST00000494851;ENST00000430881;ENST00000472804;ENST00000420541","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0046872(metal ion binding);GO:0008270(zinc ion binding);GO:0005515(protein binding);GO:0006955(immune response);GO:0006915(apoptotic process);GO:0005125(cytokine activity);GO:0005615(extracellular space);GO:0005164(tumor necrosis factor receptor binding);GO:0005576(extracellular region);GO:0070062(extracellular exosome);GO:0042802(identical protein binding);GO:0043065(positive regulation of apoptotic process);GO:0005887(integral component of plasma membrane);GO:0043123(positive regulation of I-kappaB kinase/NF-kappaB signaling);GO:0007165(signal transduction);GO:0007267(cell-cell signaling);GO:0006919(activation of cysteine-type endopeptidase activity involved in apoptotic process);GO:0007166(cell surface receptor signaling pathway);GO:0097296(activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway);GO:1902041(regulation of extrinsic apoptotic signaling pathway via death domain receptors);GO:1902042(negative regulation of extrinsic apoptotic signaling pathway via death domain receptors);GO:0005102(receptor binding);GO:0090200(positive regulation of release of cytochrome c from mitochondria);GO:0043280(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process);GO:2001238(positive regulation of extrinsic apoptotic signaling pathway);GO:0032813(tumor necrosis factor receptor superfamily binding);GO:0008584(male gonad development);GO:0032868(response to insulin);GO:0032868(response to insulin)","04068(FoxO signaling pathway);04060(Cytokine-cytokine receptor interaction);04210(Apoptosis);04217(Necroptosis);04650(Natural killer cell mediated cytotoxicity);05162(Measles);05164(Influenza A);05164(Influenza A)","K04721","NA","TNF superfamily member 10 [Source:HGNC Symbol;Acc:HGNC:11925]",{"v":10.0942866587964,"d":"10.09"},{"v":26.4992487048661,"d":"26.50"},{"v":0.380927277268158,"d":"0.38"},{"v":-1.39241249543324,"d":"-1.39"},{"v":0.0403614902342905,"d":"0.04"},{"v":0.622321466583004,"d":"0.62"},"down","yes"]
["MSTRG.5077","DMXL2","ENST00000559769;MSTRG.5077.2;ENST00000561079;ENST00000559059;ENST00000560421;ENST00000559062;ENST00000251076;ENST00000449909;ENST00000558124;ENST00000558507;ENST00000560211;ENST00000559868;ENST00000559498;ENST00000543779","GO:0016020(membrane);GO:0005615(extracellular space);GO:0030054(cell junction);GO:0045202(synapse);GO:0031410(cytoplasmic vesicle);GO:0030672(synaptic vesicle membrane);GO:0017137(Rab GTPase binding);GO:0007035(vacuolar acidification);GO:0070072(vacuolar proton-transporting V-type ATPase complex assembly);GO:0008021(synaptic vesicle);GO:0043291(RAVE complex);GO:0043291(RAVE complex)","NA","NA","NA","Dmx like 2 [Source:HGNC Symbol;Acc:HGNC:2938]",{"v":1.91507799177667,"d":"1.92"},{"v":5.03593281266681,"d":"5.04"},{"v":0.380282673144427,"d":"0.38"},{"v":-1.39485588807263,"d":"-1.39"},{"v":0.0404541135458748,"d":"0.04"},{"v":0.622951963324072,"d":"0.62"},"down","yes"]
["MSTRG.8183","CEACAM3","ENST00000595255;ENST00000599662;ENST00000357396;ENST00000630848;ENST00000415495;ENST00000599305;ENST00000596544","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0050900(leukocyte migration);GO:0005886(plasma membrane);GO:0043312(neutrophil degranulation);GO:0035579(specific granule membrane);GO:0035579(specific granule membrane)","NA","NA","NA","carcinoembryonic antigen related cell adhesion molecule 3 [Source:HGNC Symbol;Acc:HGNC:1815]",{"v":9.63330828733766,"d":"9.63"},{"v":25.2710361441558,"d":"25.27"},{"v":0.381199576953851,"d":"0.38"},{"v":-1.39138157670698,"d":"-1.39"},{"v":0.0405198650227151,"d":"0.04"},{"v":0.62316757931486,"d":"0.62"},"down","yes"]
["ENSG00000188227","ZNF793","ENST00000445217;ENST00000588578;ENST00000587986;ENST00000587143;ENST00000589319;ENST00000627814;ENST00000586138;ENST00000586187","GO:0003676(nucleic acid binding);GO:0046872(metal ion binding);GO:0006355(regulation of transcription, DNA-templated);GO:0005622(intracellular);GO:0005634(nucleus);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0003677(DNA binding)","NA","NA","NA","zinc finger protein 793 [Source:HGNC Symbol;Acc:HGNC:33115]",{"v":0.237324578329308,"d":"0.24"},{"v":0.0908524753893562,"d":"0.09"},{"v":2.61219716152183,"d":"2.61"},{"v":1.38526379168335,"d":"1.39"},{"v":0.0407557474235441,"d":"0.04"},{"v":0.623785739388133,"d":"0.62"},"up","yes"]
["MSTRG.4795","IGHV3-23","ENST00000390609","GO:0016020(membrane);GO:0005886(plasma membrane);GO:0005576(extracellular region);GO:0006508(proteolysis);GO:0006955(immune response);GO:0005615(extracellular space);GO:0002376(immune system process);GO:0003823(antigen binding);GO:0002250(adaptive immune response);GO:0004252(serine-type endopeptidase activity);GO:0006898(receptor-mediated endocytosis);GO:0006956(complement activation);GO:0006958(complement activation, classical pathway);GO:0030449(regulation of complement activation);GO:0038095(Fc-epsilon receptor signaling pathway);GO:0038096(Fc-gamma receptor signaling pathway involved in phagocytosis);GO:0050776(regulation of immune response);GO:0050900(leukocyte migration);GO:0034987(immunoglobulin receptor binding);GO:0006910(phagocytosis, recognition);GO:0006911(phagocytosis, engulfment);GO:0042742(defense response to bacterium);GO:0045087(innate immune response);GO:0050853(B cell receptor signaling pathway);GO:0050871(positive regulation of B cell activation);GO:0009897(external side of plasma membrane);GO:0042571(immunoglobulin complex, circulating);GO:0070062(extracellular exosome);GO:0072562(blood microparticle)","NA","NA","NA","immunoglobulin heavy variable 3-23 [Source:HGNC Symbol;Acc:HGNC:5588]",{"v":93.749214,"d":"93.75"},{"v":37.085228,"d":"37.09"},{"v":2.5279395343073,"d":"2.53"},{"v":1.33796195615811,"d":"1.34"},{"v":0.0407587615950864,"d":"0.04"},{"v":0.623785739388133,"d":"0.62"},"up","yes"]
["ENSG00000247982","LINC00926","ENST00000613170;ENST00000501726;ENST00000502027;ENST00000620766","NA","NA","NA","NA","long intergenic non-protein coding RNA 926 [Source:HGNC Symbol;Acc:HGNC:27514]",{"v":0.529305811937858,"d":"0.53"},{"v":1.41721316434996,"d":"1.42"},{"v":0.373483555792849,"d":"0.37"},{"v":-1.42088337127948,"d":"-1.42"},{"v":0.0407810937957302,"d":"0.04"},{"v":0.623785739388133,"d":"0.62"},"down","yes"]
["MSTRG.9981","BACH1;LINC00189","ENST00000286800;ENST00000399921;MSTRG.9981.9;ENST00000447125;ENST00000435072;ENST00000547141;ENST00000550131;ENST00000422809;ENST00000548467;ENST00000548219;ENST00000451655;ENST00000447177;ENST00000420364","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0006355(regulation of transcription, DNA-templated);GO:0006366(transcription from RNA polymerase II promoter);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0016567(protein ubiquitination);GO:0005829(cytosol);GO:0005515(protein binding);GO:0020037(heme binding);GO:0004842(ubiquitin-protein transferase activity);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0031463(Cul3-RING ubiquitin ligase complex);GO:0000980(RNA polymerase II distal enhancer sequence-specific DNA binding);GO:0001078(transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0000083(regulation of transcription involved in G1/S transition of mitotic cell cycle);GO:0000117(regulation of transcription involved in G2/M transition of mitotic cell cycle);GO:0006281(DNA repair);GO:0061418(regulation of transcription from RNA polymerase II promoter in response to hypoxia);GO:0001205(transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding);GO:0001206(transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0045944(positive regulation of transcription from RNA polymerase II promoter)","NA","NA","NA","BTB domain and CNC homolog 1 [Source:HGNC Symbol;Acc:HGNC:935];long intergenic non-protein coding RNA 189 [Source:HGNC Symbol;Acc:HGNC:18461]",{"v":4.36758024513347,"d":"4.37"},{"v":11.4377241122508,"d":"11.44"},{"v":0.381857457154034,"d":"0.38"},{"v":-1.38889389703155,"d":"-1.39"},{"v":0.0408126510802856,"d":"0.04"},{"v":0.623785739388133,"d":"0.62"},"down","yes"]
["ENSG00000213066","FGFR1OP","ENST00000496181;ENST00000488525;ENST00000476078;ENST00000494781;ENST00000349556;ENST00000366847","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0018108(peptidyl-tyrosine phosphorylation);GO:0005813(centrosome);GO:0042803(protein homodimerization activity);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0048471(perinuclear region of cytoplasm);GO:0005815(microtubule organizing center);GO:0034453(microtubule anchoring);GO:0005829(cytosol);GO:0019901(protein kinase binding);GO:0030335(positive regulation of cell migration);GO:0000086(G2/M transition of mitotic cell cycle);GO:0010389(regulation of G2/M transition of mitotic cell cycle);GO:0097711(ciliary basal body docking);GO:0008284(positive regulation of cell proliferation);GO:0030307(positive regulation of cell growth);GO:0004713(protein tyrosine kinase activity);GO:0006469(negative regulation of protein kinase activity);GO:0030292(protein tyrosine kinase inhibitor activity);GO:0061099(negative regulation of protein tyrosine kinase activity);GO:0061099(negative regulation of protein tyrosine kinase activity)","NA","NA","NA","FGFR1 oncogene partner [Source:HGNC Symbol;Acc:HGNC:17012]",{"v":0.121615010356884,"d":"0.12"},{"v":0.332327667458276,"d":"0.33"},{"v":0.365949098632159,"d":"0.37"},{"v":-1.45028510282045,"d":"-1.45"},{"v":0.0408607359402821,"d":"0.04"},{"v":0.623785739388133,"d":"0.62"},"down","yes"]
["MSTRG.13644","IKZF1","ENST00000331340;MSTRG.13644.2;ENST00000359197;MSTRG.13644.1;ENST00000343574;ENST00000484847;ENST00000612658;ENST00000357364;ENST00000438033;ENST00000413698;ENST00000492782;ENST00000346667;ENST00000349824;ENST00000462201;ENST00000641948;ENST00000440768;ENST00000492119;ENST00000471793;ENST00000439701","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0043231(intracellular membrane-bounded organelle);GO:0046872(metal ion binding);GO:0005730(nucleolus);GO:0005654(nucleoplasm);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0016569(covalent chromatin modification);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0007049(cell cycle);GO:0030218(erythrocyte differentiation);GO:0007275(multicellular organism development);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0043234(protein complex);GO:0045892(negative regulation of transcription, DNA-templated);GO:0019904(protein domain specific binding);GO:0007498(mesoderm development);GO:0044212(transcription regulatory region DNA binding);GO:0031618(nuclear pericentric heterochromatin);GO:0030098(lymphocyte differentiation);GO:0051291(protein heterooligomerization);GO:0051291(protein heterooligomerization)","NA","NA","NA","IKAROS family zinc finger 1 [Source:HGNC Symbol;Acc:HGNC:13176]",{"v":6.42492207295746,"d":"6.42"},{"v":16.8184946056107,"d":"16.82"},{"v":0.382015288741365,"d":"0.38"},{"v":-1.38829771696674,"d":"-1.39"},{"v":0.0408989991240361,"d":"0.04"},{"v":0.623785739388133,"d":"0.62"},"down","yes"]
["MSTRG.6983","GNGT2","ENST00000515635;ENST00000511673;ENST00000507680;ENST00000511277;ENST00000503070;ENST00000300406","GO:0016020(membrane);GO:0007186(G-protein coupled receptor signaling pathway);GO:0004871(signal transducer activity);GO:0005886(plasma membrane);GO:0007165(signal transduction);GO:0005834(heterotrimeric G-protein complex);GO:0003924(GTPase activity);GO:0007602(phototransduction);GO:0007602(phototransduction)","04014(Ras signaling pathway);04371(Apelin signaling pathway);04151(PI3K-Akt signaling pathway);04062(Chemokine signaling pathway);04926(Relaxin signaling pathway);04724(Glutamatergic synapse);04727(GABAergic synapse);04725(Cholinergic synapse);04728(Dopaminergic synapse);04726(Serotonergic synapse);04723(Retrograde endocannabinoid signaling);04713(Circadian entrainment);05200(Pathways in cancer);05032(Morphine addiction);05034(Alcoholism);05167(Kaposi's sarcoma-associated herpesvirus infection);05167(Kaposi's sarcoma-associated herpesvirus infection)","K04549","NA","G protein subunit gamma transducin 2 [Source:HGNC Symbol;Acc:HGNC:4412]",{"v":1.45288180165779,"d":"1.45"},{"v":0.554758970396684,"d":"0.55"},{"v":2.61894242218183,"d":"2.62"},{"v":1.38898434218341,"d":"1.39"},{"v":0.0409226651815832,"d":"0.04"},{"v":0.623785739388133,"d":"0.62"},"up","yes"]
["ENSG00000240219","AL512306.2","ENST00000444037","NA","NA","NA","NA",null,{"v":1.144713,"d":"1.14"},{"v":0.434582,"d":"0.43"},{"v":2.63405525309378,"d":"2.63"},{"v":1.39728560851331,"d":"1.40"},{"v":0.0410513271755889,"d":"0.04"},{"v":0.624955855687031,"d":"0.62"},"up","yes"]
["ENSG00000221866","PLXNA4","ENST00000359827;ENST00000321063;ENST00000378539;ENST00000423507","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0007165(signal transduction);GO:0005886(plasma membrane);GO:0017154(semaphorin receptor activity);GO:0007399(nervous system development);GO:0007411(axon guidance);GO:0008045(motor neuron axon guidance);GO:0021602(cranial nerve morphogenesis);GO:0021610(facial nerve morphogenesis);GO:0021612(facial nerve structural organization);GO:0021615(glossopharyngeal nerve morphogenesis);GO:0021636(trigeminal nerve morphogenesis);GO:0021637(trigeminal nerve structural organization);GO:0021644(vagus nerve morphogenesis);GO:0021784(postganglionic parasympathetic fiber development);GO:0021785(branchiomotor neuron axon guidance);GO:0021793(chemorepulsion of branchiomotor axon);GO:0021960(anterior commissure morphogenesis);GO:0048485(sympathetic nervous system development);GO:0048812(neuron projection morphogenesis);GO:0048841(regulation of axon extension involved in axon guidance);GO:0050923(regulation of negative chemotaxis);GO:0071526(semaphorin-plexin signaling pathway);GO:1902287(semaphorin-plexin signaling pathway involved in axon guidance);GO:0002116(semaphorin receptor complex);GO:0002116(semaphorin receptor complex)","04360(Axon guidance);04360(Axon guidance)","K06820","NA","plexin A4 [Source:HGNC Symbol;Acc:HGNC:9102]",{"v":0.304085185438554,"d":"0.30"},{"v":0.11816972165893,"d":"0.12"},{"v":2.57329188196133,"d":"2.57"},{"v":1.36361510758678,"d":"1.36"},{"v":0.0411392969387973,"d":"0.04"},{"v":0.624958446952385,"d":"0.62"},"up","yes"]
["ENSG00000004468","CD38","ENST00000226279;ENST00000511430;ENST00000502843;ENST00000510674;ENST00000506191","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016740(transferase activity);GO:0016787(hydrolase activity);GO:0045893(positive regulation of transcription, DNA-templated);GO:0005886(plasma membrane);GO:0030890(positive regulation of B cell proliferation);GO:0070062(extracellular exosome);GO:0003953(NAD+ nucleosidase activity);GO:0050135(NAD(P)+ nucleosidase activity);GO:0043066(negative regulation of apoptotic process);GO:0007165(signal transduction);GO:0045892(negative regulation of transcription, DNA-templated);GO:0050853(B cell receptor signaling pathway);GO:0097190(apoptotic signaling pathway);GO:0042493(response to drug);GO:0019674(NAD metabolic process);GO:0016849(phosphorus-oxygen lyase activity);GO:0061809(NAD+ nucleotidase, cyclic ADP-ribose generating);GO:0016798(hydrolase activity, acting on glycosyl bonds);GO:0001666(response to hypoxia);GO:0007204(positive regulation of cytosolic calcium ion concentration);GO:0007565(female pregnancy);GO:0009725(response to hormone);GO:0030307(positive regulation of cell growth);GO:0032024(positive regulation of insulin secretion);GO:0032355(response to estradiol);GO:0032526(response to retinoic acid);GO:0032570(response to progesterone);GO:0033194(response to hydroperoxide);GO:0034097(response to cytokine);GO:0045779(negative regulation of bone resorption);GO:0045907(positive regulation of vasoconstriction);GO:0060292(long term synaptic depression);GO:0070555(response to interleukin-1);GO:0005634(nucleus);GO:0009986(cell surface);GO:0043231(intracellular membrane-bounded organelle);GO:0043231(intracellular membrane-bounded organelle)","00760(Nicotinate and nicotinamide metabolism);04020(Calcium signaling pathway);04640(Hematopoietic cell lineage);04921(Oxytocin signaling pathway);04970(Salivary secretion);04972(Pancreatic secretion);05169(Epstein-Barr virus infection);05169(Epstein-Barr virus infection)","K01242","EC:3.2.2.6;EC:2.4.99.20","CD38 molecule [Source:HGNC Symbol;Acc:HGNC:1667]",{"v":2.95323903661561,"d":"2.95"},{"v":1.16400014762947,"d":"1.16"},{"v":2.53714661688832,"d":"2.54"},{"v":1.34320689241951,"d":"1.34"},{"v":0.0411621941696545,"d":"0.04"},{"v":0.624958446952385,"d":"0.62"},"up","yes"]
["ENSG00000272645","GTF2IP20","ENST00000608760;ENST00000634905","NA","NA","NA","NA","general transcription factor IIi pseudogene 20 [Source:HGNC Symbol;Acc:HGNC:51732]",{"v":0.691190236429433,"d":"0.69"},{"v":0.265451683956574,"d":"0.27"},{"v":2.60382690411754,"d":"2.60"},{"v":1.38063354494304,"d":"1.38"},{"v":0.0412376073213397,"d":"0.04"},{"v":0.624958446952385,"d":"0.62"},"up","yes"]
["MSTRG.8396","MYADM","ENST00000391771;ENST00000391770;ENST00000336967;ENST00000391769;ENST00000448420;ENST00000391768;ENST00000414489;ENST00000421337","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005886(plasma membrane);GO:0045121(membrane raft);GO:0003674(molecular_function);GO:0070062(extracellular exosome);GO:0030335(positive regulation of cell migration);GO:0001726(ruffle);GO:0010629(negative regulation of gene expression);GO:0001933(negative regulation of protein phosphorylation);GO:0061028(establishment of endothelial barrier);GO:0030864(cortical actin cytoskeleton);GO:0005911(cell-cell junction);GO:0031579(membrane raft organization);GO:0030837(negative regulation of actin filament polymerization);GO:1900026(positive regulation of substrate adhesion-dependent cell spreading);GO:0072661(protein targeting to plasma membrane);GO:0034115(negative regulation of heterotypic cell-cell adhesion);GO:0090038(negative regulation of protein kinase C signaling);GO:0090038(negative regulation of protein kinase C signaling)","NA","NA","NA","myeloid associated differentiation marker [Source:HGNC Symbol;Acc:HGNC:7544]",{"v":55.7229504092517,"d":"55.72"},{"v":145.379980389388,"d":"145.38"},{"v":0.383291772773682,"d":"0.38"},{"v":-1.38348506337036,"d":"-1.38"},{"v":0.0412905322985665,"d":"0.04"},{"v":0.624958446952385,"d":"0.62"},"down","yes"]
["ENSG00000180626","ZNF594","ENST00000576772;ENST00000399604;ENST00000575779","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0003677(DNA binding)","NA","NA","NA","zinc finger protein 594 [Source:HGNC Symbol;Acc:HGNC:29392]",{"v":0.13291142773805,"d":"0.13"},{"v":0.371526968761761,"d":"0.37"},{"v":0.357743687304914,"d":"0.36"},{"v":-1.48300178530578,"d":"-1.48"},{"v":0.0413553433552822,"d":"0.04"},{"v":0.624958446952385,"d":"0.62"},"down","yes"]
["ENSG00000113303","BTNL8","ENST00000533815;ENST00000505126;ENST00000514448;ENST00000503543;ENST00000513442;ENST00000610640;ENST00000231229","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005515(protein binding);GO:0002376(immune system process);GO:0002250(adaptive immune response);GO:0005886(plasma membrane);GO:0005886(plasma membrane)","NA","NA","NA","butyrophilin like 8 [Source:HGNC Symbol;Acc:HGNC:26131]",{"v":1.36332073267074,"d":"1.36"},{"v":3.59857636824669,"d":"3.60"},{"v":0.378850020997326,"d":"0.38"},{"v":-1.40030126703655,"d":"-1.40"},{"v":0.0413628867481358,"d":"0.04"},{"v":0.624958446952385,"d":"0.62"},"down","yes"]
["MSTRG.15396","TSC22D3","ENST00000372397;ENST00000486554;ENST00000503515;ENST00000372390;ENST00000506081;ENST00000514426;ENST00000372382;ENST00000506724;ENST00000372384;ENST00000315660;ENST00000502650;ENST00000372383;ENST00000480691","GO:0006355(regulation of transcription, DNA-templated);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0034220(ion transmembrane transport);GO:0070236(negative regulation of activation-induced cell death of T cells);GO:0043426(MRF binding);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0006970(response to osmotic stress);GO:0048642(negative regulation of skeletal muscle tissue development);GO:0048642(negative regulation of skeletal muscle tissue development)","NA","NA","NA","TSC22 domain family member 3 [Source:HGNC Symbol;Acc:HGNC:3051]",{"v":35.9606370759547,"d":"35.96"},{"v":93.7458514844733,"d":"93.75"},{"v":0.383597103301267,"d":"0.38"},{"v":-1.38233626887093,"d":"-1.38"},{"v":0.0414768200449574,"d":"0.04"},{"v":0.625894570152102,"d":"0.63"},"down","yes"]
["MSTRG.11908","TMEM192","ENST00000306480;ENST00000505095;ENST00000506087","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005654(nucleoplasm);GO:0005765(lysosomal membrane);GO:0042803(protein homodimerization activity);GO:0048471(perinuclear region of cytoplasm);GO:0005764(lysosome);GO:0005768(endosome);GO:0070062(extracellular exosome);GO:0005770(late endosome);GO:0005770(late endosome)","NA","NA","NA","transmembrane protein 192 [Source:HGNC Symbol;Acc:HGNC:26775]",{"v":1.35110054340396,"d":"1.35"},{"v":0.534029032418709,"d":"0.53"},{"v":2.53001327902454,"d":"2.53"},{"v":1.33914495706685,"d":"1.34"},{"v":0.0416228848232334,"d":"0.04"},{"v":0.627193760658268,"d":"0.63"},"up","yes"]
["MSTRG.964","S100A12","ENST00000368737","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0046872(metal ion binding);GO:0005509(calcium ion binding);GO:0005829(cytosol);GO:0008270(zinc ion binding);GO:0005886(plasma membrane);GO:0005856(cytoskeleton);GO:0005576(extracellular region);GO:0002376(immune system process);GO:0045087(innate immune response);GO:0006954(inflammatory response);GO:0042742(defense response to bacterium);GO:0006805(xenobiotic metabolic process);GO:0005515(protein binding);GO:0030593(neutrophil chemotaxis);GO:0061844(antimicrobial humoral immune response mediated by antimicrobial peptide);GO:0043312(neutrophil degranulation);GO:0043123(positive regulation of I-kappaB kinase/NF-kappaB signaling);GO:0050663(cytokine secretion);GO:0051092(positive regulation of NF-kappaB transcription factor activity);GO:0034774(secretory granule lumen);GO:0005507(copper ion binding);GO:0050729(positive regulation of inflammatory response);GO:0031640(killing of cells of other organism);GO:0043406(positive regulation of MAP kinase activity);GO:0002548(monocyte chemotaxis);GO:0050832(defense response to fungus);GO:0050786(RAGE receptor binding);GO:0045576(mast cell activation)","NA","NA","NA","S100 calcium binding protein A12 [Source:HGNC Symbol;Acc:HGNC:10489]",{"v":17.695438,"d":"17.70"},{"v":46.344772,"d":"46.34"},{"v":0.381821664803961,"d":"0.38"},{"v":-1.3890291303894,"d":"-1.39"},{"v":0.0416793710710745,"d":"0.04"},{"v":0.627193760658268,"d":"0.63"},"down","yes"]
["ENSG00000243364","EFNA4","ENST00000368409;ENST00000427683","GO:0016020(membrane);GO:0005886(plasma membrane);GO:0005576(extracellular region);GO:0031225(anchored component of membrane);GO:0046875(ephrin receptor binding);GO:0048013(ephrin receptor signaling pathway);GO:0005515(protein binding);GO:0005887(integral component of plasma membrane);GO:0007411(axon guidance);GO:0007267(cell-cell signaling);GO:0030316(osteoclast differentiation);GO:0046849(bone remodeling);GO:0005005(transmembrane-ephrin receptor activity);GO:0005005(transmembrane-ephrin receptor activity)","04014(Ras signaling pathway);04015(Rap1 signaling pathway);04010(MAPK signaling pathway);04151(PI3K-Akt signaling pathway);04360(Axon guidance);04360(Axon guidance)","K05462","NA","ephrin A4 [Source:HGNC Symbol;Acc:HGNC:3224]",{"v":1.02460731512272,"d":"1.02"},{"v":2.77322173238321,"d":"2.77"},{"v":0.369464620574067,"d":"0.37"},{"v":-1.43649187440256,"d":"-1.44"},{"v":0.0417317480258184,"d":"0.04"},{"v":0.627193760658268,"d":"0.63"},"down","yes"]
["ENSG00000167528","ZNF641","ENST00000547026;ENST00000544117;ENST00000548932;ENST00000546874;ENST00000550342;ENST00000448928;ENST00000301042;ENST00000549512","GO:0005634(nucleus);GO:0003676(nucleic acid binding);GO:0046872(metal ion binding);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0005622(intracellular);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0000981(RNA polymerase II transcription factor activity, sequence-specific DNA binding);GO:0000981(RNA polymerase II transcription factor activity, sequence-specific DNA binding)","NA","NA","NA","zinc finger protein 641 [Source:HGNC Symbol;Acc:HGNC:31834]",{"v":2.17642746943592,"d":"2.18"},{"v":0.859864658838801,"d":"0.86"},{"v":2.53112794794365,"d":"2.53"},{"v":1.33978043719898,"d":"1.34"},{"v":0.0417712502946297,"d":"0.04"},{"v":0.627193760658268,"d":"0.63"},"up","yes"]
["ENSG00000143178","TBX19","ENST00000431969;ENST00000465440;ENST00000441464;ENST00000367821","GO:0005634(nucleus);GO:0006355(regulation of transcription, DNA-templated);GO:0006366(transcription from RNA polymerase II promoter);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0009653(anatomical structure morphogenesis);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:0001077(transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0001158(enhancer sequence-specific DNA binding);GO:0021983(pituitary gland development);GO:0042127(regulation of cell proliferation);GO:0045165(cell fate commitment);GO:0045595(regulation of cell differentiation);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0045944(positive regulation of transcription from RNA polymerase II promoter)","NA","NA","NA","T-box 19 [Source:HGNC Symbol;Acc:HGNC:11596]",{"v":0.539578313682479,"d":"0.54"},{"v":0.203376983548122,"d":"0.20"},{"v":2.65309428957484,"d":"2.65"},{"v":1.40767594910026,"d":"1.41"},{"v":0.0420531774025164,"d":"0.04"},{"v":0.630336053695484,"d":"0.63"},"up","yes"]
["MSTRG.14073","TRBV11-2","MSTRG.14073.1;ENST00000471935","NA","NA","NA","NA","T-cell receptor beta variable 11-2 [Source:HGNC Symbol;Acc:HGNC:12181]",{"v":6.25433459813084,"d":"6.25"},{"v":2.41928660747664,"d":"2.42"},{"v":2.58519787560608,"d":"2.59"},{"v":1.3702747111901,"d":"1.37"},{"v":0.0420852173369182,"d":"0.04"},{"v":0.630336053695484,"d":"0.63"},"up","yes"]
["MSTRG.13220","MARCKS","ENST00000612661","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0003779(actin binding);GO:0005856(cytoskeleton);GO:0005925(focal adhesion);GO:0005516(calmodulin binding);GO:0005886(plasma membrane);GO:0070062(extracellular exosome);GO:0015629(actin cytoskeleton);GO:0050796(regulation of insulin secretion);GO:0051015(actin filament binding);GO:0005080(protein kinase C binding);GO:0042802(identical protein binding);GO:0051017(actin filament bundle assembly);GO:0051260(protein homooligomerization);GO:0051764(actin crosslink formation);GO:0005813(centrosome);GO:0005938(cell cortex);GO:0032432(actin filament bundle);GO:0042585(germinal vesicle)","04666(Fc gamma R-mediated phagocytosis);05206(MicroRNAs in cancer)","K12561","NA","myristoylated alanine rich protein kinase C substrate [Source:HGNC Symbol;Acc:HGNC:6759]",{"v":10.995233,"d":"11.00"},{"v":28.574444,"d":"28.57"},{"v":0.384792543994907,"d":"0.38"},{"v":-1.37784725016035,"d":"-1.38"},{"v":0.0422466316009015,"d":"0.04"},{"v":0.631967624519324,"d":"0.63"},"down","yes"]
["ENSG00000117724","CENPF","ENST00000366955;ENST00000469862;ENST00000464322;ENST00000614578","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0015031(protein transport);GO:0005654(nucleoplasm);GO:0051301(cell division);GO:0005694(chromosome);GO:0042803(protein homodimerization activity);GO:0008134(transcription factor binding);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0007049(cell cycle);GO:0007275(multicellular organism development);GO:0048471(perinuclear region of cytoplasm);GO:0030154(cell differentiation);GO:0000922(spindle pole);GO:0005819(spindle);GO:0030496(midbody);GO:0007059(chromosome segregation);GO:0000775(chromosome, centromeric region);GO:0000776(kinetochore);GO:0000777(condensed chromosome kinetochore);GO:0005829(cytosol);GO:0003682(chromatin binding);GO:0008283(cell proliferation);GO:0070840(dynein complex binding);GO:0007517(muscle organ development);GO:0008022(protein C-terminus binding);GO:0071897(DNA biosynthetic process);GO:0007062(sister chromatid cohesion);GO:0045892(negative regulation of transcription, DNA-templated);GO:0000785(chromatin);GO:0016363(nuclear matrix);GO:0005635(nuclear envelope);GO:0000278(mitotic cell cycle);GO:0051310(metaphase plate congression);GO:0007094(mitotic spindle assembly checkpoint);GO:0000940(condensed chromosome outer kinetochore);GO:0042493(response to drug);GO:0051726(regulation of cell cycle);GO:0016202(regulation of striated muscle tissue development);GO:0001822(kidney development);GO:0010389(regulation of G2/M transition of mitotic cell cycle);GO:0021591(ventricular system development);GO:0051382(kinetochore assembly);GO:0005813(centrosome);GO:0005930(axoneme);GO:0036064(ciliary basal body);GO:0045120(pronucleus);GO:0097539(ciliary transition fiber);GO:0097539(ciliary transition fiber)","NA","NA","NA","centromere protein F [Source:HGNC Symbol;Acc:HGNC:1857]",{"v":0.392789929426861,"d":"0.39"},{"v":0.154094499315654,"d":"0.15"},{"v":2.54901979740531,"d":"2.55"},{"v":1.34994257834542,"d":"1.35"},{"v":0.0423505762515447,"d":"0.04"},{"v":0.632736525088215,"d":"0.63"},"up","yes"]
["MSTRG.1193","FASLG","ENST00000367721;ENST00000340030","GO:0005615(extracellular space);GO:0016525(negative regulation of angiogenesis);GO:0006919(activation of cysteine-type endopeptidase activity involved in apoptotic process);GO:2000353(positive regulation of endothelial cell apoptotic process);GO:0005634(nucleus);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0005886(plasma membrane);GO:0006915(apoptotic process);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0006955(immune response);GO:0005125(cytokine activity);GO:0031410(cytoplasmic vesicle);GO:0005164(tumor necrosis factor receptor binding);GO:0005764(lysosome);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0070062(extracellular exosome);GO:0033209(tumor necrosis factor-mediated signaling pathway);GO:0043065(positive regulation of apoptotic process);GO:0005887(integral component of plasma membrane);GO:0043123(positive regulation of I-kappaB kinase/NF-kappaB signaling);GO:0007165(signal transduction);GO:0007267(cell-cell signaling);GO:0097190(apoptotic signaling pathway);GO:0097191(extrinsic apoptotic signaling pathway);GO:0097296(activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway);GO:1902041(regulation of extrinsic apoptotic signaling pathway via death domain receptors);GO:1902042(negative regulation of extrinsic apoptotic signaling pathway via death domain receptors);GO:0005102(receptor binding);GO:0043202(lysosomal lumen);GO:0060205(cytoplasmic vesicle lumen);GO:0008625(extrinsic apoptotic signaling pathway via death domain receptors);GO:0097527(necroptotic signaling pathway);GO:0005123(death receptor binding);GO:0006925(inflammatory cell apoptotic process);GO:0008284(positive regulation of cell proliferation);GO:0030644(cellular chloride ion homeostasis);GO:0032496(response to lipopolysaccharide);GO:0043525(positive regulation of neuron apoptotic process);GO:0045742(positive regulation of epidermal growth factor receptor signaling pathway);GO:0046666(retinal cell programmed cell death);GO:0048388(endosomal lumen acidification);GO:0070231(T cell apoptotic process);GO:0070266(necroptotic process);GO:0070848(response to growth factor);GO:1903514(release of sequestered calcium ion into cytosol by endoplasmic reticulum);GO:0005901(caveola);GO:0009897(external side of plasma membrane);GO:0009986(cell surface);GO:0045121(membrane raft);GO:0048471(perinuclear region of cytoplasm);GO:0048471(perinuclear region of cytoplasm)","04014(Ras signaling pathway);04010(MAPK signaling pathway);04068(FoxO signaling pathway);04151(PI3K-Akt signaling pathway);04060(Cytokine-cytokine receptor interaction);04210(Apoptosis);04217(Necroptosis);04650(Natural killer cell mediated cytotoxicity);04722(Neurotrophin signaling pathway);05200(Pathways in cancer);05205(Proteoglycans in cancer);05320(Autoimmune thyroid disease);05330(Allograft rejection);05332(Graft-versus-host disease);04940(Type I diabetes mellitus);04932(Non-alcoholic fatty liver disease (NAFLD));05162(Measles);05164(Influenza A);05161(Hepatitis B);05168(Herpes simplex infection);05165(Human papillomavirus infection);05142(Chagas disease (American trypanosomiasis));05143(African trypanosomiasis);01524(Platinum drug resistance);01524(Platinum drug resistance)","K04389","NA","Fas ligand [Source:HGNC Symbol;Acc:HGNC:11936]",{"v":5.92754059269068,"d":"5.93"},{"v":2.34151149841102,"d":"2.34"},{"v":2.53150180843151,"d":"2.53"},{"v":1.33999351486761,"d":"1.34"},{"v":0.0424480439659859,"d":"0.04"},{"v":0.633406871670882,"d":"0.63"},"up","yes"]
["ENSG00000183023","SLC8A1","ENST00000406785;ENST00000403092;ENST00000455476;ENST00000406391;ENST00000405901;ENST00000417271;ENST00000408028;ENST00000402441;ENST00000407929","GO:0010881(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion);GO:0002027(regulation of heart rate);GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0055085(transmembrane transport);GO:0046872(metal ion binding);GO:0005654(nucleoplasm);GO:0005886(plasma membrane);GO:0006811(ion transport);GO:0015297(antiporter activity);GO:0006814(sodium ion transport);GO:0006816(calcium ion transport);GO:0070588(calcium ion transmembrane transport);GO:0007154(cell communication);GO:0005509(calcium ion binding);GO:0005516(calmodulin binding);GO:0060078(regulation of postsynaptic membrane potential);GO:0005515(protein binding);GO:0005432(calcium:sodium antiporter activity);GO:0030501(positive regulation of bone mineralization);GO:0044325(ion channel binding);GO:0006936(muscle contraction);GO:1903779(regulation of cardiac conduction);GO:0042383(sarcolemma);GO:0035725(sodium ion transmembrane transport);GO:0010649(regulation of cell communication by electrical coupling);GO:0060048(cardiac muscle contraction);GO:0071313(cellular response to caffeine);GO:0030018(Z disc);GO:0070509(calcium ion import);GO:0035994(response to muscle stretch);GO:0055074(calcium ion homeostasis);GO:0030506(ankyrin binding);GO:0005887(integral component of plasma membrane);GO:0086012(membrane depolarization during cardiac muscle cell action potential);GO:0030315(T-tubule);GO:0014704(intercalated disc);GO:0008092(cytoskeletal protein binding);GO:0006883(cellular sodium ion homeostasis);GO:0055119(relaxation of cardiac muscle);GO:0086064(cell communication by electrical coupling involved in cardiac conduction);GO:0010882(regulation of cardiac muscle contraction by calcium ion signaling);GO:0002026(regulation of the force of heart contraction);GO:0098735(positive regulation of the force of heart contraction);GO:0014829(vascular smooth muscle contraction);GO:0044557(relaxation of smooth muscle);GO:0051481(negative regulation of cytosolic calcium ion concentration);GO:0055013(cardiac muscle cell development);GO:0060401(cytosolic calcium ion transport);GO:0060402(calcium ion transport into cytosol);GO:0097369(sodium ion import);GO:0099580(ion antiporter activity involved in regulation of postsynaptic membrane potential);GO:0001666(response to hypoxia);GO:0002028(regulation of sodium ion transport);GO:0006874(cellular calcium ion homeostasis);GO:0007204(positive regulation of cytosolic calcium ion concentration);GO:0007584(response to nutrient);GO:0009749(response to glucose);GO:0010763(positive regulation of fibroblast migration);GO:0021537(telencephalon development);GO:0033198(response to ATP);GO:0035902(response to immobilization stress);GO:0042493(response to drug);GO:0042542(response to hydrogen peroxide);GO:0051924(regulation of calcium ion transport);GO:0071320(cellular response to cAMP);GO:0071436(sodium ion export);GO:0071456(cellular response to hypoxia);GO:0005739(mitochondrion);GO:0005874(microtubule);GO:0042995(cell projection);GO:0043197(dendritic spine);GO:0043198(dendritic shaft);GO:0045211(postsynaptic membrane);GO:0045211(postsynaptic membrane)","04371(Apelin signaling pathway);04020(Calcium signaling pathway);04022(cGMP - PKG signaling pathway);04260(Cardiac muscle contraction);04261(Adrenergic signaling in cardiomyocytes);04974(Protein digestion and absorption);04978(Mineral absorption);04961(Endocrine and other factor-regulated calcium reabsorption);04740(Olfactory transduction);05410(Hypertrophic cardiomyopathy (HCM));05412(Arrhythmogenic right ventricular cardiomyopathy (ARVC));05414(Dilated cardiomyopathy (DCM));05414(Dilated cardiomyopathy (DCM))","K05849","NA","solute carrier family 8 member A1 [Source:HGNC Symbol;Acc:HGNC:11068]",{"v":0.448773202399416,"d":"0.45"},{"v":1.17088691757139,"d":"1.17"},{"v":0.383276297364603,"d":"0.38"},{"v":-1.38354331337269,"d":"-1.38"},{"v":0.0425542134446835,"d":"0.04"},{"v":0.633832808300024,"d":"0.63"},"down","yes"]
["MSTRG.15163","TBL1X","ENST00000217964;MSTRG.15163.7;ENST00000424279;ENST00000497555;ENST00000407597;ENST00000380961;ENST00000422314;ENST00000441088;ENST00000452824","GO:0005634(nucleus);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0005515(protein binding);GO:0006508(proteolysis);GO:0045893(positive regulation of transcription, DNA-templated);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0003714(transcription corepressor activity);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0005654(nucleoplasm);GO:0007605(sensory perception of sound);GO:0008022(protein C-terminus binding);GO:0000118(histone deacetylase complex);GO:0005876(spindle microtubule);GO:0019904(protein domain specific binding);GO:0008134(transcription factor binding);GO:0042393(histone binding);GO:0044212(transcription regulatory region DNA binding);GO:0043161(proteasome-mediated ubiquitin-dependent protein catabolic process);GO:0008013(beta-catenin binding);GO:0060070(canonical Wnt signaling pathway);GO:0019216(regulation of lipid metabolic process);GO:0017053(transcriptional repressor complex);GO:0016575(histone deacetylation);GO:0016575(histone deacetylation)","04310(Wnt signaling pathway);04310(Wnt signaling pathway)","K04508","NA","transducin beta like 1X-linked [Source:HGNC Symbol;Acc:HGNC:11585]",{"v":6.3410962924811,"d":"6.34"},{"v":16.4508529233842,"d":"16.45"},{"v":0.385456992534867,"d":"0.39"},{"v":-1.37535819484556,"d":"-1.38"},{"v":0.04258185865427,"d":"0.04"},{"v":0.633832808300024,"d":"0.63"},"down","yes"]
["MSTRG.14284","LEPROTL1;DCTN6","ENST00000321250;ENST00000523116;ENST00000221114;ENST00000518192;ENST00000520829;ENST00000520682;ENST00000522540;ENST00000519466;ENST00000519830;ENST00000522141;ENST00000518001","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005515(protein binding);GO:0005768(endosome);GO:0032511(late endosome to vacuole transport via multivesicular body sorting pathway);GO:2000009(negative regulation of protein localization to cell surface);GO:0005737(cytoplasm);GO:0005694(chromosome);GO:0005856(cytoskeleton);GO:0005813(centrosome);GO:0000775(chromosome, centromeric region);GO:0000776(kinetochore);GO:0000777(condensed chromosome kinetochore);GO:0005869(dynactin complex);GO:0005829(cytosol);GO:0019886(antigen processing and presentation of exogenous peptide antigen via MHC class II);GO:0006888(ER to Golgi vesicle-mediated transport);GO:2000009(negative regulation of protein localization to cell surface)","04962(Vasopressin-regulated water reabsorption);04962(Vasopressin-regulated water reabsorption)","K10428","NA","leptin receptor overlapping transcript like 1 [Source:HGNC Symbol;Acc:HGNC:6555];dynactin subunit 6 [Source:HGNC Symbol;Acc:HGNC:16964]",{"v":10.1562415887289,"d":"10.16"},{"v":4.06105661320095,"d":"4.06"},{"v":2.50088648252645,"d":"2.50"},{"v":1.3224395737872,"d":"1.32"},{"v":0.0429115324438625,"d":"0.04"},{"v":0.637951448998756,"d":"0.64"},"up","yes"]
["MSTRG.5276","ARID3B","MSTRG.5276.3;ENST00000346246;ENST00000563567;ENST00000566468;ENST00000569680;ENST00000622429","GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0006366(transcription from RNA polymerase II promoter);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0008150(biological_process);GO:0000977(RNA polymerase II regulatory region sequence-specific DNA binding);GO:0001228(transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:0000980(RNA polymerase II distal enhancer sequence-specific DNA binding);GO:0001077(transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0001205(transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0045944(positive regulation of transcription from RNA polymerase II promoter)","NA","NA","NA","AT-rich interaction domain 3B [Source:HGNC Symbol;Acc:HGNC:14350]",{"v":3.2959092962009,"d":"3.30"},{"v":8.54794066468126,"d":"8.55"},{"v":0.385579337233713,"d":"0.39"},{"v":-1.37490035366488,"d":"-1.37"},{"v":0.0430920272494632,"d":"0.04"},{"v":0.63833030500767,"d":"0.64"},"down","yes"]
["ENSG00000263002","ZNF234","ENST00000426739;ENST00000592437;ENST00000590795;ENST00000590748","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0005622(intracellular);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding)","NA","NA","NA","zinc finger protein 234 [Source:HGNC Symbol;Acc:HGNC:13027]",{"v":1.30148652072937,"d":"1.30"},{"v":0.513324105950096,"d":"0.51"},{"v":2.53540892711533,"d":"2.54"},{"v":1.34221845316265,"d":"1.34"},{"v":0.0431129368671609,"d":"0.04"},{"v":0.63833030500767,"d":"0.64"},"up","yes"]
["ENSG00000228784","LINC00954","ENST00000449086;ENST00000456119;ENST00000607100;ENST00000433669","NA","NA","NA","NA","long intergenic non-protein coding RNA 954 [Source:HGNC Symbol;Acc:HGNC:48668]",{"v":1.03976152658552,"d":"1.04"},{"v":0.40616976468076,"d":"0.41"},{"v":2.55991857838741,"d":"2.56"},{"v":1.35609792412185,"d":"1.36"},{"v":0.0431232259001772,"d":"0.04"},{"v":0.63833030500767,"d":"0.64"},"up","yes"]
["MSTRG.4742","IGHV3-11","ENST00000390601","GO:0016020(membrane);GO:0005886(plasma membrane);GO:0005576(extracellular region);GO:0006508(proteolysis);GO:0006955(immune response);GO:0002376(immune system process);GO:0003823(antigen binding);GO:0002250(adaptive immune response);GO:0004252(serine-type endopeptidase activity);GO:0006898(receptor-mediated endocytosis);GO:0006956(complement activation);GO:0006958(complement activation, classical pathway);GO:0030449(regulation of complement activation);GO:0038095(Fc-epsilon receptor signaling pathway);GO:0038096(Fc-gamma receptor signaling pathway involved in phagocytosis);GO:0050776(regulation of immune response);GO:0050900(leukocyte migration)","NA","NA","NA","immunoglobulin heavy variable 3-11 (gene/pseudogene) [Source:HGNC Symbol;Acc:HGNC:5580]",{"v":7.950109,"d":"7.95"},{"v":3.100751,"d":"3.10"},{"v":2.56393015756505,"d":"2.56"},{"v":1.358356962929,"d":"1.36"},{"v":0.0431490506789772,"d":"0.04"},{"v":0.63833030500767,"d":"0.64"},"up","yes"]
["MSTRG.7715","MLLT1","ENST00000252674;ENST00000587473;ENST00000585588","GO:0005634(nucleus);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0001650(fibrillar center);GO:0005515(protein binding);GO:0003677(DNA binding);GO:0006366(transcription from RNA polymerase II promoter);GO:0006368(transcription elongation from RNA polymerase II promoter);GO:0008023(transcription elongation factor complex);GO:0006469(negative regulation of protein kinase activity);GO:0006469(negative regulation of protein kinase activity)","05202(Transcriptional misregulation in cancers);05202(Transcriptional misregulation in cancers)","K15187","NA","MLLT1, super elongation complex subunit [Source:HGNC Symbol;Acc:HGNC:7134]",{"v":3.38006173291139,"d":"3.38"},{"v":8.7575517,"d":"8.76"},{"v":0.3859596664341,"d":"0.39"},{"v":-1.37347800406715,"d":"-1.37"},{"v":0.0432731594436337,"d":"0.04"},{"v":0.639213253214993,"d":"0.64"},"down","yes"]
["MSTRG.14808","ALDH1A1","ENST00000297785;ENST00000376939;ENST00000482210;ENST00000446946;ENST00000419959;ENST00000493113","GO:0005737(cytoplasm);GO:0000166(nucleotide binding);GO:0005829(cytosol);GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0008152(metabolic process);GO:0043547(positive regulation of GTPase activity);GO:0005096(GTPase activator activity);GO:0070062(extracellular exosome);GO:0006081(cellular aldehyde metabolic process);GO:0001758(retinal dehydrogenase activity);GO:0004029(aldehyde dehydrogenase (NAD) activity);GO:0042572(retinol metabolic process);GO:0006069(ethanol oxidation);GO:0005497(androgen binding);GO:0018479(benzaldehyde dehydrogenase (NAD+) activity);GO:0051287(NAD binding);GO:0001523(retinoid metabolic process);GO:0061624(fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate);GO:0061624(fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate)","00830(Retinol metabolism);00830(Retinol metabolism)","K07249","EC:1.2.1.36","aldehyde dehydrogenase 1 family member A1 [Source:HGNC Symbol;Acc:HGNC:402]",{"v":3.38433183046683,"d":"3.38"},{"v":8.80117672621973,"d":"8.80"},{"v":0.384531743395688,"d":"0.38"},{"v":-1.37882539618208,"d":"-1.38"},{"v":0.043314899071868,"d":"0.04"},{"v":0.639213253214993,"d":"0.64"},"down","yes"]
["ENSG00000130517","PGPEP1","ENST00000269919;ENST00000595066;ENST00000597431;ENST00000600283;ENST00000252813;ENST00000604499;ENST00000595552;ENST00000597663","GO:0005737(cytoplasm);GO:0016787(hydrolase activity);GO:0005829(cytosol);GO:0008233(peptidase activity);GO:0008234(cysteine-type peptidase activity);GO:0006508(proteolysis);GO:0016920(pyroglutamyl-peptidase activity);GO:0016920(pyroglutamyl-peptidase activity)","NA","NA","NA","pyroglutamyl-peptidase I [Source:HGNC Symbol;Acc:HGNC:13568]",{"v":2.72666315691489,"d":"2.73"},{"v":1.08896452340426,"d":"1.09"},{"v":2.50390448753183,"d":"2.50"},{"v":1.32417953112346,"d":"1.32"},{"v":0.0434520387668631,"d":"0.04"},{"v":0.640452204198979,"d":"0.64"},"up","yes"]
["ENSG00000139531","SUOX","ENST00000552813;ENST00000550121;ENST00000548274;ENST00000551698;ENST00000394115;ENST00000546833;ENST00000394109;ENST00000266971;ENST00000546712;ENST00000356124;ENST00000547586","GO:0046872(metal ion binding);GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0005739(mitochondrion);GO:0005515(protein binding);GO:0020037(heme binding);GO:0030151(molybdenum ion binding);GO:0043546(molybdopterin cofactor binding);GO:0042128(nitrate assimilation);GO:0005758(mitochondrial intermembrane space);GO:0005759(mitochondrial matrix);GO:0006790(sulfur compound metabolic process);GO:0070221(sulfide oxidation, using sulfide:quinone oxidoreductase);GO:0008482(sulfite oxidase activity);GO:0008482(sulfite oxidase activity)","00920(Sulfur metabolism);00920(Sulfur metabolism)","K00387","EC:1.8.3.1","sulfite oxidase [Source:HGNC Symbol;Acc:HGNC:11460]",{"v":0.419551972843451,"d":"0.42"},{"v":1.12017754692492,"d":"1.12"},{"v":0.374540602063658,"d":"0.37"},{"v":-1.41680597240951,"d":"-1.42"},{"v":0.0435253279458684,"d":"0.04"},{"v":0.640748165188444,"d":"0.64"},"down","yes"]
["ENSG00000138160","KIF11","ENST00000260731","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0005829(cytosol);GO:0051301(cell division);GO:0003777(microtubule motor activity);GO:0005856(cytoskeleton);GO:0007049(cell cycle);GO:0008017(microtubule binding);GO:0005874(microtubule);GO:0007018(microtubule-based movement);GO:0000922(spindle pole);GO:0005819(spindle);GO:0019901(protein kinase binding);GO:0006890(retrograde vesicle-mediated transport, Golgi to ER);GO:0019886(antigen processing and presentation of exogenous peptide antigen via MHC class II);GO:0090307(mitotic spindle assembly);GO:0032403(protein complex binding);GO:0008574(ATP-dependent microtubule motor activity, plus-end-directed);GO:0046602(regulation of mitotic centrosome separation);GO:0000278(mitotic cell cycle);GO:0005871(kinesin complex);GO:0007051(spindle organization);GO:0007059(chromosome segregation);GO:0007052(mitotic spindle organization);GO:0005876(spindle microtubule);GO:0007100(mitotic centrosome separation);GO:0051225(spindle assembly)","NA","NA","NA","kinesin family member 11 [Source:HGNC Symbol;Acc:HGNC:6388]",{"v":0.535289,"d":"0.54"},{"v":0.205526,"d":"0.21"},{"v":2.60448313108804,"d":"2.60"},{"v":1.38099709296328,"d":"1.38"},{"v":0.0436308846801781,"d":"0.04"},{"v":0.641517842879981,"d":"0.64"},"up","yes"]
["ENSG00000100346","CACNA1I","ENST00000402142","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0055085(transmembrane transport);GO:0005216(ion channel activity);GO:0006811(ion transport);GO:0030317(flagellated sperm motility);GO:0005244(voltage-gated ion channel activity);GO:0034765(regulation of ion transmembrane transport);GO:0005515(protein binding);GO:0035725(sodium ion transmembrane transport);GO:0006816(calcium ion transport);GO:0070588(calcium ion transmembrane transport);GO:0005245(voltage-gated calcium channel activity);GO:0005262(calcium channel activity);GO:0005891(voltage-gated calcium channel complex);GO:0060078(regulation of postsynaptic membrane potential);GO:0008332(low voltage-gated calcium channel activity);GO:0070509(calcium ion import);GO:0005886(plasma membrane);GO:0007165(signal transduction);GO:0086010(membrane depolarization during action potential);GO:0005248(voltage-gated sodium channel activity);GO:0019228(neuronal action potential);GO:0045956(positive regulation of calcium ion-dependent exocytosis);GO:0030431(sleep)","04010(MAPK signaling pathway);04020(Calcium signaling pathway);04925(Aldosterone synthesis and secretion);04927(Cortisol synthesis and secretion);04713(Circadian entrainment)","K04856","NA","calcium voltage-gated channel subunit alpha1 I [Source:HGNC Symbol;Acc:HGNC:1396]",{"v":0.722083565974796,"d":"0.72"},{"v":0.285850024462565,"d":"0.29"},{"v":2.52609237075423,"d":"2.53"},{"v":1.33690739462528,"d":"1.34"},{"v":0.0437096813402378,"d":"0.04"},{"v":0.641892661828224,"d":"0.64"},"up","yes"]
["MSTRG.801","FAM212B","ENST00000357260;ENST00000444059;ENST00000527621;ENST00000527570","GO:0005634(nucleus);GO:0071901(negative regulation of protein serine/threonine kinase activity);GO:0019901(protein kinase binding);GO:0030291(protein serine/threonine kinase inhibitor activity);GO:0030291(protein serine/threonine kinase inhibitor activity)","NA","NA","NA","family with sequence similarity 212 member B [Source:HGNC Symbol;Acc:HGNC:28045]",{"v":2.5937778397256,"d":"2.59"},{"v":1.0362932595884,"d":"1.04"},{"v":2.50293805901604,"d":"2.50"},{"v":1.32362258864666,"d":"1.32"},{"v":0.043929859774403,"d":"0.04"},{"v":0.642738752387059,"d":"0.64"},"up","yes"]
["MSTRG.11913","DDX60L","ENST00000511577;ENST00000512958;ENST00000515088;MSTRG.11913.1;ENST00000505890;ENST00000514748;ENST00000512371;ENST00000510590;ENST00000260184;ENST00000503190;ENST00000513103;ENST00000505696;ENST00000513901;ENST00000505863;ENST00000505150;MSTRG.11913.5","GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0016787(hydrolase activity);GO:0004386(helicase activity);GO:0004386(helicase activity)","NA","NA","NA","DEAD-box helicase 60 like [Source:HGNC Symbol;Acc:HGNC:26429]",{"v":2.04060529198736,"d":"2.04"},{"v":5.26956022952281,"d":"5.27"},{"v":0.387243945055383,"d":"0.39"},{"v":-1.36868541366946,"d":"-1.37"},{"v":0.0439750241284019,"d":"0.04"},{"v":0.642738752387059,"d":"0.64"},"down","yes"]
["MSTRG.8418","LILRA5;AC245884.11;LILRA4;VN1R104P;AC245884.6","ENST00000432233;ENST00000446712;ENST00000616950;ENST00000421056;ENST00000477720;ENST00000489504;ENST00000505115;ENST00000291759;ENST00000595581;ENST00000515672;ENST00000486742","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005886(plasma membrane);GO:0005576(extracellular region);GO:0002376(immune system process);GO:0045087(innate immune response);GO:0070062(extracellular exosome);GO:0005515(protein binding);GO:0002250(adaptive immune response);GO:0070062(extracellular exosome)","04380(Osteoclast differentiation);04380(Osteoclast differentiation)","K06512","NA","leukocyte immunoglobulin like receptor A5 [Source:HGNC Symbol;Acc:HGNC:16309];leukocyte immunoglobulin like receptor A4 [Source:HGNC Symbol;Acc:HGNC:15503];vomeronasal 1 receptor 104 pseudogene [Source:HGNC Symbol;Acc:HGNC:37427]",{"v":3.65851325977934,"d":"3.66"},{"v":9.46302533471844,"d":"9.46"},{"v":0.386611377479546,"d":"0.39"},{"v":-1.37104400003922,"d":"-1.37"},{"v":0.0439771968645955,"d":"0.04"},{"v":0.642738752387059,"d":"0.64"},"down","yes"]
["MSTRG.1487","ZBTB18","ENST00000622512;ENST00000358704","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0005654(nucleoplasm);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0045171(intercellular bridge);GO:0015630(microtubule cytoskeleton);GO:0005515(protein binding);GO:0007275(multicellular organism development);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0043565(sequence-specific DNA binding);GO:0045892(negative regulation of transcription, DNA-templated);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0007519(skeletal muscle tissue development);GO:0000228(nuclear chromosome);GO:0000228(nuclear chromosome)","NA","NA","NA","zinc finger and BTB domain containing 18 [Source:HGNC Symbol;Acc:HGNC:13030]",{"v":7.62510599462366,"d":"7.63"},{"v":19.6755555796211,"d":"19.68"},{"v":0.387542093221568,"d":"0.39"},{"v":-1.36757507641301,"d":"-1.37"},{"v":0.043980794881825,"d":"0.04"},{"v":0.642738752387059,"d":"0.64"},"down","yes"]
["MSTRG.14983","FPGS","ENST00000475765;ENST00000630236;ENST00000373247;ENST00000373225;ENST00000393706;ENST00000496586;ENST00000473536;ENST00000431857;ENST00000488307;ENST00000469310;ENST00000497386;ENST00000467826;ENST00000373228;ENST00000460181;ENST00000475270;ENST00000489522;ENST00000479147","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0005743(mitochondrial inner membrane);GO:0009058(biosynthetic process);GO:0005739(mitochondrion);GO:0006730(one-carbon metabolic process);GO:0016874(ligase activity);GO:0005759(mitochondrial matrix);GO:0005829(cytosol);GO:0006139(nucleobase-containing compound metabolic process);GO:0046655(folic acid metabolic process);GO:0006536(glutamate metabolic process);GO:0004326(tetrahydrofolylpolyglutamate synthase activity);GO:0001889(liver development);GO:0006760(folic acid-containing compound metabolic process);GO:0007420(brain development);GO:0009396(folic acid-containing compound biosynthetic process);GO:0031100(animal organ regeneration);GO:0046901(tetrahydrofolylpolyglutamate biosynthetic process);GO:0046901(tetrahydrofolylpolyglutamate biosynthetic process)","00790(Folate biosynthesis);01523(Antifolate resistance);01523(Antifolate resistance)","K01930","EC:6.3.2.17","folylpolyglutamate synthase [Source:HGNC Symbol;Acc:HGNC:3824]",{"v":6.6559450496057,"d":"6.66"},{"v":2.65976762833884,"d":"2.66"},{"v":2.50245358981329,"d":"2.50"},{"v":1.32334331327022,"d":"1.32"},{"v":0.044219554269569,"d":"0.04"},{"v":0.643863183764715,"d":"0.64"},"up","yes"]
["MSTRG.15070","SURF4","ENST00000371989;ENST00000613129;ENST00000371991;ENST00000465565;ENST00000618229;ENST00000371982;ENST00000485435;ENST00000545297","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005794(Golgi apparatus);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005515(protein binding);GO:0000139(Golgi membrane);GO:0005886(plasma membrane);GO:0006890(retrograde vesicle-mediated transport, Golgi to ER);GO:0043312(neutrophil degranulation);GO:0030133(transport vesicle);GO:0035577(azurophil granule membrane);GO:0007030(Golgi organization);GO:0010638(positive regulation of organelle organization);GO:0005793(endoplasmic reticulum-Golgi intermediate compartment);GO:0033116(endoplasmic reticulum-Golgi intermediate compartment membrane);GO:0033116(endoplasmic reticulum-Golgi intermediate compartment membrane)","NA","NA","NA","surfeit 4 [Source:HGNC Symbol;Acc:HGNC:11476]",{"v":23.0611142159025,"d":"23.06"},{"v":9.27912574114916,"d":"9.28"},{"v":2.48526799390548,"d":"2.49"},{"v":1.31340143031141,"d":"1.31"},{"v":0.0442215414180996,"d":"0.04"},{"v":0.643863183764715,"d":"0.64"},"up","yes"]
["MSTRG.13988","C7orf49","MSTRG.13988.7;ENST00000472428;ENST00000464070;ENST00000617987;ENST00000393114;ENST00000487774;ENST00000459937;ENST00000481410;ENST00000424142;ENST00000488161;ENST00000486115;ENST00000483029","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005515(protein binding);GO:0006281(DNA repair);GO:0006974(cellular response to DNA damage stimulus);GO:0006303(double-strand break repair via nonhomologous end joining);GO:0006303(double-strand break repair via nonhomologous end joining)","NA","NA","NA","chromosome 7 open reading frame 49 [Source:HGNC Symbol;Acc:HGNC:22432]",{"v":2.69140906552567,"d":"2.69"},{"v":1.0712153409943,"d":"1.07"},{"v":2.51248181624015,"d":"2.51"},{"v":1.32911315501193,"d":"1.33"},{"v":0.044238909471811,"d":"0.04"},{"v":0.643863183764715,"d":"0.64"},"up","yes"]
["MSTRG.11546","BST1;FAM200B","MSTRG.11546.25;ENST00000265016;ENST00000622362;ENST00000422728;ENST00000503617;ENST00000382346;ENST00000514445;ENST00000510920;ENST00000502502;ENST00000512855;ENST00000504137;ENST00000504598;ENST00000510186;ENST00000505260;ENST00000504823;ENST00000515697;ENST00000514803;ENST00000502856;ENST00000515430;ENST00000503600;ENST00000509022;ENST00000514989;ENST00000507305;ENST00000505785;ENST00000513053;ENST00000506610;ENST00000508567;ENST00000507992;ENST00000510032","GO:0016020(membrane);GO:0016740(transferase activity);GO:0016787(hydrolase activity);GO:0005886(plasma membrane);GO:0031225(anchored component of membrane);GO:0005576(extracellular region);GO:0070062(extracellular exosome);GO:0003953(NAD+ nucleosidase activity);GO:0006501(C-terminal protein lipidation);GO:0043312(neutrophil degranulation);GO:0035579(specific granule membrane);GO:0032956(regulation of actin cytoskeleton organization);GO:0019674(NAD metabolic process);GO:0050848(regulation of calcium-mediated signaling);GO:0008284(positive regulation of cell proliferation);GO:0016849(phosphorus-oxygen lyase activity);GO:0050135(NAD(P)+ nucleosidase activity);GO:0061809(NAD+ nucleotidase, cyclic ADP-ribose generating);GO:0008305(integrin complex);GO:0061811(ADP-ribosyl cyclase activity);GO:0061812(cyclic ADP-ribose hydrolase);GO:0001952(regulation of cell-matrix adhesion);GO:0002691(regulation of cellular extravasation);GO:0006959(humoral immune response);GO:0007165(signal transduction);GO:0030890(positive regulation of B cell proliferation);GO:0050727(regulation of inflammatory response);GO:0050730(regulation of peptidyl-tyrosine phosphorylation);GO:0090022(regulation of neutrophil chemotaxis);GO:0090322(regulation of superoxide metabolic process);GO:2001044(regulation of integrin-mediated signaling pathway);GO:0001931(uropod);GO:0019898(extrinsic component of membrane);GO:0003676(nucleic acid binding);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0005737(cytoplasm);GO:0000981(RNA polymerase II transcription factor activity, sequence-specific DNA binding);GO:0005654(nucleoplasm);GO:0003677(DNA binding);GO:0003677(DNA binding)","00760(Nicotinate and nicotinamide metabolism);04970(Salivary secretion);04972(Pancreatic secretion);04972(Pancreatic secretion)","K18152","EC:3.2.2.6;EC:2.4.99.20","bone marrow stromal cell antigen 1 [Source:HGNC Symbol;Acc:HGNC:1118];family with sequence similarity 200 member B [Source:HGNC Symbol;Acc:HGNC:27740]",{"v":3.52550758985283,"d":"3.53"},{"v":9.10202859411309,"d":"9.10"},{"v":0.387332071460753,"d":"0.39"},{"v":-1.36835713206549,"d":"-1.37"},{"v":0.044271609048097,"d":"0.04"},{"v":0.643863183764715,"d":"0.64"},"down","yes"]
["MSTRG.5285","PPCDC","ENST00000563393;ENST00000563298;ENST00000562192;ENST00000567336;ENST00000342932;ENST00000569562;ENST00000564923;ENST00000568207;ENST00000568649;ENST00000564953","GO:0003824(catalytic activity);GO:0016829(lyase activity);GO:0005515(protein binding);GO:0016831(carboxy-lyase activity);GO:0042802(identical protein binding);GO:0005829(cytosol);GO:0009108(coenzyme biosynthetic process);GO:0015937(coenzyme A biosynthetic process);GO:0004633(phosphopantothenoylcysteine decarboxylase activity);GO:0004633(phosphopantothenoylcysteine decarboxylase activity)","00770(Pantothenate and CoA biosynthesis);00770(Pantothenate and CoA biosynthesis)","K01598","EC:4.1.1.36","phosphopantothenoylcysteine decarboxylase [Source:HGNC Symbol;Acc:HGNC:28107]",{"v":0.85789650886009,"d":"0.86"},{"v":2.24918819227718,"d":"2.25"},{"v":0.38142495670472,"d":"0.38"},{"v":-1.39052885234785,"d":"-1.39"},{"v":0.044705605056941,"d":"0.04"},{"v":0.648822007496957,"d":"0.65"},"down","yes"]
["ENSG00000118507","AKAP7","ENST00000431975;ENST00000541650;ENST00000543815;ENST00000479599;ENST00000537868;ENST00000366358;ENST00000474850;ENST00000263050","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0000166(nucleotide binding);GO:0005829(cytosol);GO:0005515(protein binding);GO:0008150(biological_process);GO:0008104(protein localization);GO:0051018(protein kinase A binding);GO:0010738(regulation of protein kinase A signaling);GO:0034237(protein kinase A regulatory subunit binding);GO:0019901(protein kinase binding);GO:0005622(intracellular);GO:0016020(membrane);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0005886(plasma membrane);GO:0016328(lateral plasma membrane);GO:0016324(apical plasma membrane);GO:0035556(intracellular signal transduction);GO:0060306(regulation of membrane repolarization);GO:0001508(action potential);GO:0006811(ion transport);GO:0071320(cellular response to cAMP);GO:1901381(positive regulation of potassium ion transmembrane transport);GO:1902261(positive regulation of delayed rectifier potassium channel activity);GO:1902261(positive regulation of delayed rectifier potassium channel activity)","NA","NA","NA","A-kinase anchoring protein 7 [Source:HGNC Symbol;Acc:HGNC:377]",{"v":0.614094868912153,"d":"0.61"},{"v":0.234387122894857,"d":"0.23"},{"v":2.62000258942394,"d":"2.62"},{"v":1.38956823762045,"d":"1.39"},{"v":0.0447203343483204,"d":"0.04"},{"v":0.648822007496957,"d":"0.65"},"up","yes"]
["ENSG00000128000","ZNF780B","ENST00000617676;ENST00000434248;ENST00000594811;ENST00000593605;ENST00000598845;ENST00000595995;ENST00000221355","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0005622(intracellular);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding)","NA","NA","NA","zinc finger protein 780B [Source:HGNC Symbol;Acc:HGNC:33109]",{"v":0.277735373114896,"d":"0.28"},{"v":0.727377296951286,"d":"0.73"},{"v":0.381831237074611,"d":"0.38"},{"v":-1.38899296247237,"d":"-1.39"},{"v":0.0448125653052873,"d":"0.04"},{"v":0.649076240158572,"d":"0.65"},"down","yes"]
["MSTRG.1974","SHOC2","ENST00000369452;ENST00000265277;ENST00000489390;ENST00000497305;ENST00000451838;ENST00000480155;ENST00000489783","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0050790(regulation of catalytic activity);GO:0005515(protein binding);GO:0007265(Ras protein signal transduction);GO:0019903(protein phosphatase binding);GO:0046579(positive regulation of Ras protein signal transduction);GO:0008543(fibroblast growth factor receptor signaling pathway);GO:0019888(protein phosphatase regulator activity);GO:0000164(protein phosphatase type 1 complex);GO:0008157(protein phosphatase 1 binding);GO:0008157(protein phosphatase 1 binding)","04014(Ras signaling pathway);04014(Ras signaling pathway)","K19613","NA","SHOC2, leucine rich repeat scaffold protein [Source:HGNC Symbol;Acc:HGNC:15454]",{"v":4.5417327859562,"d":"4.54"},{"v":11.6910901727252,"d":"11.69"},{"v":0.388478124696349,"d":"0.39"},{"v":-1.36409473249797,"d":"-1.36"},{"v":0.0448456595093781,"d":"0.04"},{"v":0.649076240158572,"d":"0.65"},"down","yes"]
["MSTRG.7798","AC114271.1","ENST00000612689","NA","NA","NA","NA",null,{"v":0.913322,"d":"0.91"},{"v":2.377033,"d":"2.38"},{"v":0.384227732639808,"d":"0.38"},{"v":-1.3799664418444,"d":"-1.38"},{"v":0.0450074878115057,"d":"0.05"},{"v":0.650421677366613,"d":"0.65"},"down","yes"]
["MSTRG.8722","REL;AC010733.2","ENST00000394479;ENST00000295025;ENST00000589496","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0006355(regulation of transcription, DNA-templated);GO:0006366(transcription from RNA polymerase II promoter);GO:0045893(positive regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0005515(protein binding);GO:0045087(innate immune response);GO:0003682(chromatin binding);GO:0006954(inflammatory response);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0043123(positive regulation of I-kappaB kinase/NF-kappaB signaling);GO:0034097(response to cytokine);GO:0007249(I-kappaB kinase/NF-kappaB signaling);GO:0000980(RNA polymerase II distal enhancer sequence-specific DNA binding);GO:0001205(transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding);GO:0038061(NIK/NF-kappaB signaling);GO:0010629(negative regulation of gene expression);GO:0032688(negative regulation of interferon-beta production);GO:0033256(I-kappaB/NF-kappaB complex);GO:0043565(sequence-specific DNA binding);GO:1901215(negative regulation of neuron death);GO:0005667(transcription factor complex);GO:0005667(transcription factor complex)","04014(Ras signaling pathway);05202(Transcriptional misregulation in cancers);05203(Viral carcinogenesis);05203(Viral carcinogenesis)","K09254","NA","REL proto-oncogene, NF-kB subunit [Source:HGNC Symbol;Acc:HGNC:9954]",{"v":1.28865972900933,"d":"1.29"},{"v":3.31593211585962,"d":"3.32"},{"v":0.388626691977757,"d":"0.39"},{"v":-1.36354310219499,"d":"-1.36"},{"v":0.0450466433253409,"d":"0.05"},{"v":0.650421677366613,"d":"0.65"},"down","yes"]
["MSTRG.1253","NCF2","ENST00000367535;ENST00000419402;ENST00000413720;ENST00000469280;ENST00000367536;ENST00000420553;ENST00000418089","GO:0005737(cytoplasm);GO:0005730(nucleolus);GO:0005829(cytosol);GO:0055114(oxidation-reduction process);GO:0043085(positive regulation of catalytic activity);GO:0005515(protein binding);GO:0006909(phagocytosis);GO:0016176(superoxide-generating NADPH oxidase activator activity);GO:0045730(respiratory burst);GO:0043020(NADPH oxidase complex);GO:0002479(antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent);GO:0008022(protein C-terminus binding);GO:0045087(innate immune response);GO:0048010(vascular endothelial growth factor receptor signaling pathway);GO:0009055(electron carrier activity);GO:0034599(cellular response to oxidative stress);GO:0006968(cellular defense response);GO:0006801(superoxide metabolic process);GO:0042554(superoxide anion generation);GO:0045454(cell redox homeostasis);GO:0032010(phagolysosome);GO:0016175(superoxide-generating NADPH oxidase activity);GO:0048365(Rac GTPase binding);GO:0001669(acrosomal vesicle);GO:0001669(acrosomal vesicle)","04145(Phagosome);04670(Leukocyte transendothelial migration);04380(Osteoclast differentiation);05418(Fluid shear stress and atherosclerosis);05140(Leishmaniasis);05140(Leishmaniasis)","K08010","NA","neutrophil cytosolic factor 2 [Source:HGNC Symbol;Acc:HGNC:7661]",{"v":69.9538700467896,"d":"69.95"},{"v":179.193763892418,"d":"179.19"},{"v":0.390381163536403,"d":"0.39"},{"v":-1.35704465245847,"d":"-1.36"},{"v":0.0452698825588552,"d":"0.05"},{"v":0.651724361491825,"d":"0.65"},"down","yes"]
["MSTRG.15400","ACSL4;KCNE5","ENST00000348502;ENST00000514500;ENST00000504383;ENST00000439581;ENST00000372101;ENST00000502391;ENST00000505075;ENST00000340800;ENST00000505855;ENST00000469796","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0003824(catalytic activity);GO:0006629(lipid metabolic process);GO:0008152(metabolic process);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0006631(fatty acid metabolic process);GO:0005739(mitochondrion);GO:0016874(ligase activity);GO:0005741(mitochondrial outer membrane);GO:0001676(long-chain fatty acid metabolic process);GO:0005777(peroxisome);GO:0005778(peroxisomal membrane);GO:0043231(intracellular membrane-bounded organelle);GO:0070062(extracellular exosome);GO:0035338(long-chain fatty-acyl-CoA biosynthetic process);GO:0031090(organelle membrane);GO:0005811(lipid particle);GO:0004467(long-chain fatty acid-CoA ligase activity);GO:0031957(very long-chain fatty acid-CoA ligase activity);GO:0102391(decanoate--CoA ligase activity);GO:0047676(arachidonate-CoA ligase activity);GO:0044233(ER-mitochondrion membrane contact site);GO:0006641(triglyceride metabolic process);GO:0007584(response to nutrient);GO:0015908(fatty acid transport);GO:0030182(neuron differentiation);GO:0060136(embryonic process involved in female pregnancy);GO:0060996(dendritic spine development);GO:0070672(response to interleukin-15);GO:0031966(mitochondrial membrane);GO:0043025(neuronal cell body);GO:0008016(regulation of heart contraction);GO:0060307(regulation of ventricular cardiac muscle cell membrane repolarization);GO:0006811(ion transport);GO:0005249(voltage-gated potassium channel activity);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0044325(ion channel binding);GO:0060048(cardiac muscle contraction);GO:0060306(regulation of membrane repolarization);GO:0008076(voltage-gated potassium channel complex);GO:0086091(regulation of heart rate by cardiac conduction);GO:1901381(positive regulation of potassium ion transmembrane transport);GO:0015459(potassium channel regulator activity);GO:0060372(regulation of atrial cardiac muscle cell membrane repolarization);GO:0086008(voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization);GO:0071435(potassium ion export);GO:0071805(potassium ion transmembrane transport);GO:0086005(ventricular cardiac muscle cell action potential);GO:1901379(regulation of potassium ion transmembrane transport);GO:0086014(atrial cardiac muscle cell action potential);GO:1901380(negative regulation of potassium ion transmembrane transport);GO:2001257(regulation of cation channel activity);GO:0086013(membrane repolarization during cardiac muscle cell action potential);GO:0043025(neuronal cell body)","00061(Fatty acid biosynthesis);00071(Fatty acid degradation);04146(Peroxisome);04216(Ferroptosis);04920(Adipocytokine signaling pathway);03320(PPAR signaling pathway);03320(PPAR signaling pathway)","K01897","EC:6.2.1.3","acyl-CoA synthetase long chain family member 4 [Source:HGNC Symbol;Acc:HGNC:3571];potassium voltage-gated channel subfamily E regulatory subunit 5 [Source:HGNC Symbol;Acc:HGNC:6241]",{"v":2.68022064622279,"d":"2.68"},{"v":6.88770542752881,"d":"6.89"},{"v":0.389131137274029,"d":"0.39"},{"v":-1.36167166920644,"d":"-1.36"},{"v":0.0452739702913534,"d":"0.05"},{"v":0.651724361491825,"d":"0.65"},"down","yes"]
["MSTRG.5586","DNASE1","ENST00000407479;ENST00000570520;ENST00000570807;ENST00000570769;ENST00000573804;ENST00000570761;ENST00000246949;ENST00000575479;ENST00000576792;ENST00000570376;ENST00000576050","GO:0004536(deoxyribonuclease activity);GO:0006308(DNA catabolic process);GO:0005634(nucleus);GO:0016787(hydrolase activity);GO:0003779(actin binding);GO:0090305(nucleic acid phosphodiester bond hydrolysis);GO:0005576(extracellular region);GO:0006915(apoptotic process);GO:0004519(endonuclease activity);GO:0004518(nuclease activity);GO:0005515(protein binding);GO:0070062(extracellular exosome);GO:0005635(nuclear envelope);GO:0004530(deoxyribonuclease I activity);GO:0004530(deoxyribonuclease I activity)","NA","NA","NA","deoxyribonuclease 1 [Source:HGNC Symbol;Acc:HGNC:2956]",{"v":0.194156929063111,"d":"0.19"},{"v":0.514825433736686,"d":"0.51"},{"v":0.377131579638342,"d":"0.38"},{"v":-1.40686013326997,"d":"-1.41"},{"v":0.0452992269198354,"d":"0.05"},{"v":0.651724361491825,"d":"0.65"},"down","yes"]
["ENSG00000238113","LINC01410","ENST00000424345;ENST00000452184;ENST00000427509","NA","NA","NA","NA","long intergenic non-protein coding RNA 1410 [Source:HGNC Symbol;Acc:HGNC:50702]",{"v":0.946684658327847,"d":"0.95"},{"v":2.47031638973009,"d":"2.47"},{"v":0.38322405270172,"d":"0.38"},{"v":-1.38373998155729,"d":"-1.38"},{"v":0.0453617946338995,"d":"0.05"},{"v":0.651845741027945,"d":"0.65"},"down","yes"]
["MSTRG.3680","CMKLR1","ENST00000312143;ENST00000550402;ENST00000412676;MSTRG.3680.1;ENST00000549466;ENST00000550573","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0004930(G-protein coupled receptor activity);GO:0007186(G-protein coupled receptor signaling pathway);GO:0005886(plasma membrane);GO:0004871(signal transducer activity);GO:0007165(signal transduction);GO:0070098(chemokine-mediated signaling pathway);GO:0006935(chemotaxis);GO:0005515(protein binding);GO:0032088(negative regulation of NF-kappaB transcription factor activity);GO:0005887(integral component of plasma membrane);GO:0006955(immune response);GO:0004872(receptor activity);GO:0001501(skeletal system development);GO:0004950(chemokine receptor activity);GO:0045600(positive regulation of fat cell differentiation);GO:0050848(regulation of calcium-mediated signaling);GO:0032695(negative regulation of interleukin-12 production);GO:0010759(positive regulation of macrophage chemotaxis);GO:0010759(positive regulation of macrophage chemotaxis)","NA","NA","NA","chemerin chemokine-like receptor 1 [Source:HGNC Symbol;Acc:HGNC:2121]",{"v":0.898745009087792,"d":"0.90"},{"v":2.32540634807956,"d":"2.33"},{"v":0.386489445094197,"d":"0.39"},{"v":-1.37149907974937,"d":"-1.37"},{"v":0.0454979566876754,"d":"0.05"},{"v":0.653023116129902,"d":"0.65"},"down","yes"]
["MSTRG.7276","TNRC6C","ENST00000636222;ENST00000587990;ENST00000592566;ENST00000592251;ENST00000335749;ENST00000591851;ENST00000588847;ENST00000585438;ENST00000301624","GO:0003676(nucleic acid binding);GO:0035278(miRNA mediated inhibition of translation);GO:0035195(gene silencing by miRNA);GO:0003723(RNA binding);GO:0005515(protein binding);GO:0031047(gene silencing by RNA);GO:0005829(cytosol);GO:0006417(regulation of translation);GO:0060213(positive regulation of nuclear-transcribed mRNA poly(A) tail shortening);GO:1900153(positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay);GO:0038111(interleukin-7-mediated signaling pathway);GO:0048015(phosphatidylinositol-mediated signaling);GO:0045652(regulation of megakaryocyte differentiation);GO:0007223(Wnt signaling pathway, calcium modulating pathway);GO:0035194(posttranscriptional gene silencing by RNA);GO:0035194(posttranscriptional gene silencing by RNA)","NA","NA","NA","trinucleotide repeat containing 6C [Source:HGNC Symbol;Acc:HGNC:29318]",{"v":3.52529804689047,"d":"3.53"},{"v":1.4256712501125,"d":"1.43"},{"v":2.47272858073857,"d":"2.47"},{"v":1.30610389087532,"d":"1.31"},{"v":0.0456639492923879,"d":"0.05"},{"v":0.654625330213019,"d":"0.65"},"up","yes"]
["ENSG00000138376","BARD1","ENST00000260947;ENST00000432456;ENST00000479904","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016607(nuclear speck);GO:0046872(metal ion binding);GO:0016740(transferase activity);GO:0016567(protein ubiquitination);GO:0042803(protein homodimerization activity);GO:0005515(protein binding);GO:0006281(DNA repair);GO:0006974(cellular response to DNA damage stimulus);GO:0000932(P-body);GO:0043065(positive regulation of apoptotic process);GO:0031436(BRCA1-BARD1 complex);GO:0005654(nucleoplasm);GO:0016579(protein deubiquitination);GO:0007050(cell cycle arrest);GO:0043066(negative regulation of apoptotic process);GO:0004842(ubiquitin-protein transferase activity);GO:0046982(protein heterodimerization activity);GO:1901796(regulation of signal transduction by p53 class mediator);GO:0006260(DNA replication);GO:0000151(ubiquitin ligase complex);GO:0000731(DNA synthesis involved in DNA repair);GO:0000732(strand displacement);GO:0019900(kinase binding);GO:0085020(protein K6-linked ubiquitination);GO:0001894(tissue homeostasis);GO:0042325(regulation of phosphorylation);GO:0000729(DNA double-strand break processing);GO:0006303(double-strand break repair via nonhomologous end joining);GO:0045732(positive regulation of protein catabolic process);GO:0003723(RNA binding);GO:0046826(negative regulation of protein export from nucleus);GO:0070531(BRCA1-A complex);GO:0031441(negative regulation of mRNA 3'-end processing);GO:0031441(negative regulation of mRNA 3'-end processing)","03440(Homologous recombination);03440(Homologous recombination)","K10683","NA","BRCA1 associated RING domain 1 [Source:HGNC Symbol;Acc:HGNC:952]",{"v":0.175434766441404,"d":"0.18"},{"v":0.472431259601121,"d":"0.47"},{"v":0.371344535053683,"d":"0.37"},{"v":-1.42916974805403,"d":"-1.43"},{"v":0.0457433465323001,"d":"0.05"},{"v":0.654983803735979,"d":"0.65"},"down","yes"]
["MSTRG.2140","OR52K3P","MSTRG.2140.1;ENST00000641797","NA","NA","NA","NA","olfactory receptor family 52 subfamily K member 3 pseudogene [Source:HGNC Symbol;Acc:HGNC:15224]",{"v":2.35967862,"d":"2.36"},{"v":6.10387227666667,"d":"6.10"},{"v":0.386587155340777,"d":"0.39"},{"v":-1.37113439120788,"d":"-1.37"},{"v":0.0458676307114608,"d":"0.05"},{"v":0.655251835563159,"d":"0.66"},"down","yes"]
["MSTRG.15039",null,"MSTRG.15039.1","NA","NA","NA","NA",null,{"v":5.365153,"d":"5.37"},{"v":2.039545,"d":"2.04"},{"v":2.63056367964423,"d":"2.63"},{"v":1.39537197468588,"d":"1.40"},{"v":0.0459042827453169,"d":"0.05"},{"v":0.655251835563159,"d":"0.66"},"up","yes"]
["MSTRG.9696","MMP24","MSTRG.9696.1","NA","NA","NA","NA",null,{"v":3.388813,"d":"3.39"},{"v":9.201156,"d":"9.20"},{"v":0.368302961062719,"d":"0.37"},{"v":-1.4410350986996,"d":"-1.44"},{"v":0.0460140622829131,"d":"0.05"},{"v":0.655251835563159,"d":"0.66"},"down","yes"]
["MSTRG.8468","AC020915.4","ENST00000597230","NA","NA","NA","NA",null,{"v":0.7373,"d":"0.74"},{"v":0.284223,"d":"0.28"},{"v":2.59408985198242,"d":"2.59"},{"v":1.37522845135694,"d":"1.38"},{"v":0.0460140622829131,"d":"0.05"},{"v":0.655251835563159,"d":"0.66"},"up","yes"]
["MSTRG.2025","CHST15","ENST00000346248;ENST00000435907;MSTRG.2025.3;ENST00000628426;ENST00000476765;ENST00000462406","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016740(transferase activity);GO:0005794(Golgi apparatus);GO:0000139(Golgi membrane);GO:0030206(chondroitin sulfate biosynthetic process);GO:0050656(3'-phosphoadenosine 5'-phosphosulfate binding);GO:0050659(N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase activity);GO:0019319(hexose biosynthetic process);GO:0019319(hexose biosynthetic process)","00532(Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate);00532(Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate)","K08106","EC:2.8.2.33","carbohydrate sulfotransferase 15 [Source:HGNC Symbol;Acc:HGNC:18137]",{"v":10.0097422142535,"d":"10.01"},{"v":25.5683923700195,"d":"25.57"},{"v":0.391488916056785,"d":"0.39"},{"v":-1.3529566327766,"d":"-1.35"},{"v":0.0460772416061216,"d":"0.05"},{"v":0.655251835563159,"d":"0.66"},"down","yes"]
["ENSG00000124191","TOX2","ENST00000341197;ENST00000372999;ENST00000413823;ENST00000358131","GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0006366(transcription from RNA polymerase II promoter);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0001077(transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0001077(transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding)","NA","NA","NA","TOX high mobility group box family member 2 [Source:HGNC Symbol;Acc:HGNC:16095]",{"v":0.72246485789637,"d":"0.72"},{"v":0.279673186472231,"d":"0.28"},{"v":2.58324677817515,"d":"2.58"},{"v":1.36918547103754,"d":"1.37"},{"v":0.0461282269060239,"d":"0.05"},{"v":0.655251835563159,"d":"0.66"},"up","yes"]
["MSTRG.5295","SNX33","ENST00000308527","GO:0006810(transport);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0006886(intracellular protein transport);GO:0015031(protein transport);GO:0006897(endocytosis);GO:0051301(cell division);GO:0005829(cytosol);GO:0005515(protein binding);GO:0007049(cell cycle);GO:0030659(cytoplasmic vesicle membrane);GO:0031410(cytoplasmic vesicle);GO:0035091(phosphatidylinositol binding);GO:0042802(identical protein binding);GO:0000281(mitotic cytokinesis);GO:0000278(mitotic cell cycle);GO:0016197(endosomal transport);GO:0019898(extrinsic component of membrane);GO:2000009(negative regulation of protein localization to cell surface);GO:0007032(endosome organization);GO:0097320(plasma membrane tubulation);GO:2000010(positive regulation of protein localization to cell surface);GO:0044351(macropinocytosis);GO:0036089(cleavage furrow formation);GO:0051044(positive regulation of membrane protein ectodomain proteolysis);GO:0045806(negative regulation of endocytosis);GO:0017038(protein import);GO:0005622(intracellular)","NA","NA","NA","sorting nexin 33 [Source:HGNC Symbol;Acc:HGNC:28468]",{"v":0.395336,"d":"0.40"},{"v":1.025948,"d":"1.03"},{"v":0.385337268555521,"d":"0.39"},{"v":-1.37580636941402,"d":"-1.38"},{"v":0.0461429626770934,"d":"0.05"},{"v":0.655251835563159,"d":"0.66"},"down","yes"]
["MSTRG.53","LINC01128","ENST00000445118;ENST00000609009;ENST00000425657;ENST00000448975;ENST00000449005;ENST00000608189;ENST00000622921;ENST00000415295;ENST00000624927;ENST00000441765;ENST00000416570","NA","NA","NA","NA","long intergenic non-protein coding RNA 1128 [Source:HGNC Symbol;Acc:HGNC:49377]",{"v":0.877908906124604,"d":"0.88"},{"v":0.351290470538543,"d":"0.35"},{"v":2.49909684364262,"d":"2.50"},{"v":1.32140680904199,"d":"1.32"},{"v":0.0463219521116372,"d":"0.05"},{"v":0.656491608007874,"d":"0.66"},"up","yes"]
["MSTRG.3105","SLC2A3","ENST00000075120;ENST00000479059;ENST00000490763;ENST00000541671;ENST00000544291;ENST00000544936;ENST00000495813;ENST00000469295;ENST00000476634;ENST00000486749","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005215(transporter activity);GO:0055085(transmembrane transport);GO:0005886(plasma membrane);GO:0022857(transmembrane transporter activity);GO:0022891(substrate-specific transmembrane transporter activity);GO:0008643(carbohydrate transport);GO:0005887(integral component of plasma membrane);GO:0005355(glucose transmembrane transporter activity);GO:0070062(extracellular exosome);GO:0043312(neutrophil degranulation);GO:0035579(specific granule membrane);GO:0070821(tertiary granule membrane);GO:0005975(carbohydrate metabolic process);GO:0030667(secretory granule membrane);GO:0101003(ficolin-1-rich granule membrane);GO:0055056(D-glucose transmembrane transporter activity);GO:0019852(L-ascorbic acid metabolic process);GO:0015758(glucose transport);GO:0005536(glucose binding);GO:0033300(dehydroascorbic acid transporter activity);GO:1904659(glucose transmembrane transport);GO:0070837(dehydroascorbic acid transport);GO:0070837(dehydroascorbic acid transport)","NA","NA","NA","solute carrier family 2 member 3 [Source:HGNC Symbol;Acc:HGNC:11007]",{"v":14.2842589527521,"d":"14.28"},{"v":36.4410459738594,"d":"36.44"},{"v":0.391982682467423,"d":"0.39"},{"v":-1.35113817644037,"d":"-1.35"},{"v":0.0463393013458473,"d":"0.05"},{"v":0.656491608007874,"d":"0.66"},"down","yes"]
["MSTRG.13179","CD24","ENST00000621311;ENST00000620405;ENST00000622315;ENST00000610952;ENST00000606017;ENST00000619133","GO:0007155(cell adhesion);GO:0007155(cell adhesion)","04640(Hematopoietic cell lineage);04640(Hematopoietic cell lineage)","K06469","NA","CD24 molecule [Source:HGNC Symbol;Acc:HGNC:1645]",{"v":2.19585555989667,"d":"2.20"},{"v":5.64566681465935,"d":"5.65"},{"v":0.388945297691848,"d":"0.39"},{"v":-1.36236082990239,"d":"-1.36"},{"v":0.0465401817999881,"d":"0.05"},{"v":0.657575867509521,"d":"0.66"},"down","yes"]
["MSTRG.14586","NDRG1","ENST00000323851;ENST00000519278;ENST00000521438;ENST00000522476;ENST00000518094;ENST00000519580;ENST00000521414;ENST00000517745;ENST00000518176;ENST00000521544;ENST00000521664;ENST00000519228;ENST00000522665;ENST00000518480;ENST00000521026;ENST00000520230;ENST00000523931;ENST00000522377;ENST00000523642;ENST00000522738;ENST00000518066;ENST00000414097","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0015630(microtubule cytoskeleton);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0048471(perinuclear region of cytoplasm);GO:0005874(microtubule);GO:0008017(microtubule binding);GO:0005813(centrosome);GO:0005815(microtubule organizing center);GO:0045296(cadherin binding);GO:0070062(extracellular exosome);GO:0042127(regulation of cell proliferation);GO:0055038(recycling endosome membrane);GO:0032287(peripheral nervous system myelin maintenance);GO:0045576(mast cell activation);GO:0042981(regulation of apoptotic process);GO:0030330(DNA damage response, signal transduction by p53 class mediator);GO:0071456(cellular response to hypoxia);GO:0017137(Rab GTPase binding);GO:0043015(gamma-tubulin binding);GO:0005913(cell-cell adherens junction);GO:0010038(response to metal ion);GO:0090232(positive regulation of spindle checkpoint);GO:0008285(negative regulation of cell proliferation);GO:0043209(myelin sheath);GO:0043209(myelin sheath)","NA","NA","NA","N-myc downstream regulated 1 [Source:HGNC Symbol;Acc:HGNC:7679]",{"v":4.21691907380637,"d":"4.22"},{"v":10.7554919738369,"d":"10.76"},{"v":0.392071239889739,"d":"0.39"},{"v":-1.35081227703241,"d":"-1.35"},{"v":0.046638019879821,"d":"0.05"},{"v":0.657575867509521,"d":"0.66"},"down","yes"]
["ENSG00000187808","SOWAHD","ENST00000343905","NA","NA","NA","NA","sosondowah ankyrin repeat domain family member D [Source:HGNC Symbol;Acc:HGNC:32960]",{"v":1.248247,"d":"1.25"},{"v":3.249034,"d":"3.25"},{"v":0.38419019314664,"d":"0.38"},{"v":-1.38010740170194,"d":"-1.38"},{"v":0.0466829523900233,"d":"0.05"},{"v":0.657575867509521,"d":"0.66"},"down","yes"]
["ENSG00000154359","LONRF1","ENST00000398246;ENST00000524526;ENST00000534446;ENST00000527055;ENST00000526610;ENST00000533751","GO:0046872(metal ion binding);GO:0005515(protein binding);GO:0005622(intracellular);GO:0061630(ubiquitin protein ligase activity);GO:0005829(cytosol);GO:0000209(protein polyubiquitination);GO:0004842(ubiquitin-protein transferase activity);GO:0032436(positive regulation of proteasomal ubiquitin-dependent protein catabolic process);GO:0031624(ubiquitin conjugating enzyme binding);GO:0031624(ubiquitin conjugating enzyme binding)","NA","NA","NA","LON peptidase N-terminal domain and ring finger 1 [Source:HGNC Symbol;Acc:HGNC:26302]",{"v":0.247524086543536,"d":"0.25"},{"v":0.662351984520668,"d":"0.66"},{"v":0.373704755671057,"d":"0.37"},{"v":-1.42002917168411,"d":"-1.42"},{"v":0.0466986249429584,"d":"0.05"},{"v":0.657575867509521,"d":"0.66"},"down","yes"]
["MSTRG.12786","MCCD1P1;HLA-F-AS1","MSTRG.12786.2;MSTRG.12786.1","NA","NA","NA","NA",null,{"v":2.5677416124031,"d":"2.57"},{"v":6.88854406976744,"d":"6.89"},{"v":0.372755343712244,"d":"0.37"},{"v":-1.4236990601737,"d":"-1.42"},{"v":0.0467053460051146,"d":"0.05"},{"v":0.657575867509521,"d":"0.66"},"down","yes"]
["MSTRG.11909","KLHL2","ENST00000226725;ENST00000511305;ENST00000509028;ENST00000506541;ENST00000506761;ENST00000538127;ENST00000421009;ENST00000509704","GO:0005737(cytoplasm);GO:0016567(protein ubiquitination);GO:0003779(actin binding);GO:0005829(cytosol);GO:0005856(cytoskeleton);GO:0042995(cell projection);GO:0005515(protein binding);GO:0042802(identical protein binding);GO:0004842(ubiquitin-protein transferase activity);GO:0030027(lamellipodium);GO:0043687(post-translational protein modification);GO:0031463(Cul3-RING ubiquitin ligase complex);GO:0042787(protein ubiquitination involved in ubiquitin-dependent protein catabolic process);GO:0001726(ruffle);GO:0015629(actin cytoskeleton);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016021(integral component of membrane)","NA","NA","NA","kelch like family member 2 [Source:HGNC Symbol;Acc:HGNC:6353]",{"v":3.52857752918388,"d":"3.53"},{"v":9.02103635821281,"d":"9.02"},{"v":0.39114990662591,"d":"0.39"},{"v":-1.35420647431564,"d":"-1.35"},{"v":0.0469183639781532,"d":"0.05"},{"v":0.657575867509521,"d":"0.66"},"down","yes"]
["MSTRG.12692","FAM8A1","ENST00000259963","GO:0016020(membrane);GO:0016021(integral component of membrane)","NA","NA","NA","family with sequence similarity 8 member A1 [Source:HGNC Symbol;Acc:HGNC:16372]",{"v":5.214828,"d":"5.21"},{"v":13.280132,"d":"13.28"},{"v":0.392678928191376,"d":"0.39"},{"v":-1.34857791223689,"d":"-1.35"},{"v":0.0469282013381318,"d":"0.05"},{"v":0.657575867509521,"d":"0.66"},"down","yes"]
["ENSG00000212719","C17orf51","ENST00000391411","NA","NA","NA","NA","chromosome 17 open reading frame 51 [Source:HGNC Symbol;Acc:HGNC:27904]",{"v":0.521198332876712,"d":"0.52"},{"v":0.207685584246575,"d":"0.21"},{"v":2.50955469426284,"d":"2.51"},{"v":1.32743138912666,"d":"1.33"},{"v":0.0469892753478609,"d":"0.05"},{"v":0.657575867509521,"d":"0.66"},"up","yes"]
["MSTRG.10901","PFKFB4;UCN2","ENST00000232375;ENST00000383734;ENST00000490115;ENST00000416568;ENST00000478516;ENST00000417753;ENST00000471890;ENST00000412035;ENST00000273610;ENST00000467176;ENST00000452531;ENST00000422701;ENST00000490404;ENST00000468162","GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0016787(hydrolase activity);GO:0003824(catalytic activity);GO:0008152(metabolic process);GO:0016311(dephosphorylation);GO:0006003(fructose 2,6-bisphosphate metabolic process);GO:0006000(fructose metabolic process);GO:0046835(carbohydrate phosphorylation);GO:0003873(6-phosphofructo-2-kinase activity);GO:0005829(cytosol);GO:0004331(fructose-2,6-bisphosphate 2-phosphatase activity);GO:0045821(positive regulation of glycolytic process);GO:0005615(extracellular space);GO:0005576(extracellular region);GO:0005179(hormone activity);GO:0006950(response to stress);GO:0007586(digestion);GO:0006171(cAMP biosynthetic process);GO:0001664(G-protein coupled receptor binding);GO:0005102(receptor binding);GO:0042562(hormone binding);GO:0007189(adenylate cyclase-activating G-protein coupled receptor signaling pathway);GO:0051431(corticotropin-releasing hormone receptor 2 binding);GO:0031669(cellular response to nutrient levels);GO:0045821(positive regulation of glycolytic process)","00051(Fructose and mannose metabolism);04152(AMPK signaling pathway);04080(Neuroactive ligand-receptor interaction);04152(AMPK signaling pathway)","K19030;K05257","EC:2.7.1.105;EC:3.1.3.46","6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 [Source:HGNC Symbol;Acc:HGNC:8875];urocortin 2 [Source:HGNC Symbol;Acc:HGNC:18414]",{"v":2.41471639484861,"d":"2.41"},{"v":6.16950220989177,"d":"6.17"},{"v":0.391395660897408,"d":"0.39"},{"v":-1.35330033288404,"d":"-1.35"},{"v":0.0470192084292937,"d":"0.05"},{"v":0.657575867509521,"d":"0.66"},"down","yes"]
["MSTRG.13990","TMEM140","ENST00000275767;ENST00000466307","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005515(protein binding);GO:0005515(protein binding)","NA","NA","NA","transmembrane protein 140 [Source:HGNC Symbol;Acc:HGNC:21870]",{"v":13.8796636515348,"d":"13.88"},{"v":35.3165361452659,"d":"35.32"},{"v":0.393007502050717,"d":"0.39"},{"v":-1.34737124279009,"d":"-1.35"},{"v":0.04707354365151,"d":"0.05"},{"v":0.657575867509521,"d":"0.66"},"down","yes"]
["MSTRG.10549","RRP7BP","ENST00000357802;ENST00000458605;ENST00000421116;ENST00000437211;ENST00000566851","NA","NA","NA","NA","ribosomal RNA processing 7 homolog B, pseudogene [Source:HGNC Symbol;Acc:HGNC:30454]",{"v":1.83223105047133,"d":"1.83"},{"v":0.735611164179104,"d":"0.74"},{"v":2.49076025445588,"d":"2.49"},{"v":1.31658616314712,"d":"1.32"},{"v":0.0470909858611144,"d":"0.05"},{"v":0.657575867509521,"d":"0.66"},"up","yes"]
["ENSG00000234616","JRK","ENST00000612905;ENST00000503272;ENST00000585503;ENST00000591180;ENST00000614134;ENST00000615982;ENST00000587883","GO:0003676(nucleic acid binding);GO:0003677(DNA binding);GO:0003729(mRNA binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0030529(intracellular ribonucleoprotein complex);GO:0030529(intracellular ribonucleoprotein complex)","NA","NA","NA","Jrk helix-turn-helix protein [Source:HGNC Symbol;Acc:HGNC:6199]",{"v":1.13121890693739,"d":"1.13"},{"v":0.45383756229406,"d":"0.45"},{"v":2.4925634211926,"d":"2.49"},{"v":1.31763021325978,"d":"1.32"},{"v":0.047178965913609,"d":"0.05"},{"v":0.657575867509521,"d":"0.66"},"up","yes"]
["MSTRG.2939","SORL1","MSTRG.2939.1;ENST00000530365;ENST00000260197;ENST00000527934;ENST00000528339;ENST00000532694;ENST00000529445;ENST00000534754;ENST00000524873;ENST00000532451;ENST00000527649;ENST00000524633;ENST00000525532","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005794(Golgi apparatus);GO:0006629(lipid metabolic process);GO:0008202(steroid metabolic process);GO:0005576(extracellular region);GO:0005615(extracellular space);GO:0006869(lipid transport);GO:0008203(cholesterol metabolic process);GO:0007165(signal transduction);GO:0005515(protein binding);GO:0005768(endosome);GO:0006897(endocytosis);GO:0070062(extracellular exosome);GO:0044267(cellular protein metabolic process);GO:0010008(endosome membrane);GO:0005887(integral component of plasma membrane);GO:0006605(protein targeting);GO:0000139(Golgi membrane);GO:0004888(transmembrane signaling receptor activity);GO:0006898(receptor-mediated endocytosis);GO:0005041(low-density lipoprotein receptor activity);GO:0030169(low-density lipoprotein particle binding);GO:0034362(low-density lipoprotein particle);GO:1901215(negative regulation of neuron death);GO:1902430(negative regulation of amyloid-beta formation);GO:0005641(nuclear envelope lumen);GO:0001540(amyloid-beta binding);GO:1902963(negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process);GO:0030306(ADP-ribosylation factor binding);GO:0000042(protein targeting to Golgi);GO:0006622(protein targeting to lysosome);GO:0006892(post-Golgi vesicle-mediated transport);GO:0014910(regulation of smooth muscle cell migration);GO:0032091(negative regulation of protein binding);GO:0032460(negative regulation of protein oligomerization);GO:0043407(negative regulation of MAP kinase activity);GO:0045053(protein retention in Golgi apparatus);GO:0045732(positive regulation of protein catabolic process);GO:0050768(negative regulation of neurogenesis);GO:0051604(protein maturation);GO:0070863(positive regulation of protein exit from endoplasmic reticulum);GO:1902771(positive regulation of choline O-acetyltransferase activity);GO:1902948(negative regulation of tau-protein kinase activity);GO:1902953(positive regulation of ER to Golgi vesicle-mediated transport);GO:1902955(positive regulation of early endosome to recycling endosome transport);GO:1902960(negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process);GO:1902966(positive regulation of protein localization to early endosome);GO:1902997(negative regulation of neurofibrillary tangle assembly);GO:2001137(positive regulation of endocytic recycling);GO:0005769(early endosome);GO:0005783(endoplasmic reticulum);GO:0005802(trans-Golgi network);GO:0031985(Golgi cisterna);GO:0055037(recycling endosome);GO:0055037(recycling endosome)","NA","NA","NA","sortilin related receptor 1 [Source:HGNC Symbol;Acc:HGNC:11185]",{"v":17.1130303433723,"d":"17.11"},{"v":43.4727077016282,"d":"43.47"},{"v":0.393649975999341,"d":"0.39"},{"v":-1.34501470462315,"d":"-1.35"},{"v":0.0471827922412956,"d":"0.05"},{"v":0.657575867509521,"d":"0.66"},"down","yes"]
["ENSG00000118785","SPP1","ENST00000395080;ENST00000509659;ENST00000237623;ENST00000614857;ENST00000508002;ENST00000505146","GO:0005615(extracellular space);GO:0007566(embryo implantation);GO:0005794(Golgi apparatus);GO:0007155(cell adhesion);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0005125(cytokine activity);GO:0001503(ossification);GO:0070062(extracellular exosome);GO:0031214(biomineral tissue development);GO:0044267(cellular protein metabolic process);GO:0043687(post-translational protein modification);GO:0005788(endoplasmic reticulum lumen);GO:0030198(extracellular matrix organization);GO:0022617(extracellular matrix disassembly);GO:0045893(positive regulation of transcription, DNA-templated);GO:0033280(response to vitamin D);GO:0046697(decidualization);GO:0050840(extracellular matrix binding);GO:0001649(osteoblast differentiation);GO:0006710(androgen catabolic process);GO:0045780(positive regulation of bone resorption);GO:0071394(cellular response to testosterone stimulus);GO:2000866(positive regulation of estradiol secretion);GO:0006954(inflammatory response);GO:0010033(response to organic substance);GO:0030154(cell differentiation);GO:0048545(response to steroid hormone);GO:0048685(negative regulation of collateral sprouting of intact axon in response to injury);GO:0031982(vesicle);GO:0042995(cell projection);GO:0048471(perinuclear region of cytoplasm);GO:0048471(perinuclear region of cytoplasm)","04371(Apelin signaling pathway);04151(PI3K-Akt signaling pathway);04512(ECM-receptor interaction);04510(Focal adhesion);04620(Toll-like receptor signaling pathway);05165(Human papillomavirus infection);05165(Human papillomavirus infection)","K06250","NA","secreted phosphoprotein 1 [Source:HGNC Symbol;Acc:HGNC:11255]",{"v":0.444701277897458,"d":"0.44"},{"v":1.18086083110728,"d":"1.18"},{"v":0.376590760047877,"d":"0.38"},{"v":-1.40893049216475,"d":"-1.41"},{"v":0.0472109980512844,"d":"0.05"},{"v":0.657575867509521,"d":"0.66"},"down","yes"]
["MSTRG.2400","DTX4","ENST00000227451;ENST00000527475;ENST00000531902","GO:0005737(cytoplasm);GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0016740(transferase activity);GO:0016567(protein ubiquitination);GO:0007219(Notch signaling pathway);GO:0005829(cytosol);GO:0004842(ubiquitin-protein transferase activity);GO:0032479(regulation of type I interferon production);GO:0032479(regulation of type I interferon production)","04330(Notch signaling pathway);04330(Notch signaling pathway)","K06058","EC:2.3.2.27","deltex E3 ubiquitin ligase 4 [Source:HGNC Symbol;Acc:HGNC:29151]",{"v":0.52578449571805,"d":"0.53"},{"v":1.35965169927536,"d":"1.36"},{"v":0.386705283418005,"d":"0.39"},{"v":-1.37069361929808,"d":"-1.37"},{"v":0.0473375070652997,"d":"0.05"},{"v":0.657575867509521,"d":"0.66"},"down","yes"]
["ENSG00000167555","ZNF528","ENST00000598479;ENST00000493272;ENST00000448954;ENST00000360465;ENST00000598192;ENST00000479718;ENST00000391788;ENST00000494167;ENST00000436397;ENST00000594530;ENST00000391787","GO:0003676(nucleic acid binding);GO:0006355(regulation of transcription, DNA-templated);GO:0005622(intracellular);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding)","NA","NA","NA","zinc finger protein 528 [Source:HGNC Symbol;Acc:HGNC:29384]",{"v":0.476644688628371,"d":"0.48"},{"v":0.190088452754982,"d":"0.19"},{"v":2.5074889175028,"d":"2.51"},{"v":1.32624332448687,"d":"1.33"},{"v":0.0473642825033296,"d":"0.05"},{"v":0.657575867509521,"d":"0.66"},"up","yes"]
["MSTRG.10686","NR2C2","ENST00000617312;ENST00000323373;ENST00000393102;ENST00000475707;ENST00000406272;ENST00000478572;ENST00000439011;ENST00000437120;ENST00000413194;ENST00000425241;ENST00000435454;ENST00000413118;ENST00000495282","GO:0005634(nucleus);GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0005654(nucleoplasm);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0043565(sequence-specific DNA binding);GO:0003707(steroid hormone receptor activity);GO:0043401(steroid hormone mediated signaling pathway);GO:0030154(cell differentiation);GO:0007283(spermatogenesis);GO:0005515(protein binding);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0001228(transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding);GO:0007399(nervous system development);GO:0003713(transcription coactivator activity);GO:0004872(receptor activity);GO:0046982(protein heterodimerization activity);GO:0006367(transcription initiation from RNA polymerase II promoter);GO:0001077(transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0000977(RNA polymerase II regulatory region sequence-specific DNA binding);GO:0000977(RNA polymerase II regulatory region sequence-specific DNA binding)","NA","NA","NA","nuclear receptor subfamily 2 group C member 2 [Source:HGNC Symbol;Acc:HGNC:7972]",{"v":1.5445433816936,"d":"1.54"},{"v":3.93393794196768,"d":"3.93"},{"v":0.392620169529428,"d":"0.39"},{"v":-1.34879380661549,"d":"-1.35"},{"v":0.0473955799156347,"d":"0.05"},{"v":0.657575867509521,"d":"0.66"},"down","yes"]
["MSTRG.4017","RPL13AP25","ENST00000484130","NA","NA","NA","NA","ribosomal protein L13a pseudogene 25 [Source:HGNC Symbol;Acc:HGNC:36981]",{"v":63.563793,"d":"63.56"},{"v":25.914371,"d":"25.91"},{"v":2.45283950746866,"d":"2.45"},{"v":1.29445283954005,"d":"1.29"},{"v":0.047398758760859,"d":"0.05"},{"v":0.657575867509521,"d":"0.66"},"up","yes"]
["ENSG00000104497","SNX16","ENST00000519817;ENST00000519212;ENST00000353788;ENST00000523757;ENST00000345957;ENST00000396330","GO:0006810(transport);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0015031(protein transport);GO:0005829(cytosol);GO:0043231(intracellular membrane-bounded organelle);GO:0035091(phosphatidylinositol binding);GO:0005764(lysosome);GO:0008289(lipid binding);GO:0005768(endosome);GO:0031902(late endosome membrane);GO:0008333(endosome to lysosome transport);GO:0042802(identical protein binding);GO:0005769(early endosome);GO:0005770(late endosome);GO:0031901(early endosome membrane);GO:0006622(protein targeting to lysosome);GO:0031313(extrinsic component of endosome membrane);GO:0045022(early endosome to late endosome transport);GO:0045022(early endosome to late endosome transport)","NA","NA","NA","sorting nexin 16 [Source:HGNC Symbol;Acc:HGNC:14980]",{"v":0.282095061822126,"d":"0.28"},{"v":0.747135218221258,"d":"0.75"},{"v":0.377568952637146,"d":"0.38"},{"v":-1.4051879576187,"d":"-1.41"},{"v":0.0475138225635379,"d":"0.05"},{"v":0.657758046181462,"d":"0.66"},"down","yes"]
["MSTRG.14226","TNFRSF10A","MSTRG.14226.1","NA","NA","NA","NA",null,{"v":3.648137,"d":"3.65"},{"v":9.610738,"d":"9.61"},{"v":0.379589683955592,"d":"0.38"},{"v":-1.39748730987381,"d":"-1.40"},{"v":0.0475288887432572,"d":"0.05"},{"v":0.657758046181462,"d":"0.66"},"down","yes"]
["MSTRG.3171","KLRC4-KLRK1;KLRK1;KLRC4","MSTRG.3171.2;ENST00000240618;ENST00000544449;ENST00000396451;ENST00000586581;MSTRG.3171.1;ENST00000590323;ENST00000539300;ENST00000588447;ENST00000540267;ENST00000539370;ENST00000309384;ENST00000585711;ENST00000591546;MSTRG.3171.3;ENST00000590131;ENST00000543572;ENST00000540818","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0030246(carbohydrate binding);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0030154(cell differentiation);GO:0002376(immune system process);GO:0045087(innate immune response);GO:0032394(MHC class Ib receptor activity);GO:0042288(MHC class I protein binding);GO:0042803(protein homodimerization activity);GO:0002223(stimulatory C-type lectin receptor signaling pathway);GO:0030101(natural killer cell activation);GO:0032729(positive regulation of interferon-gamma production);GO:0045429(positive regulation of nitric oxide biosynthetic process);GO:0045954(positive regulation of natural killer cell mediated cytotoxicity);GO:0050830(defense response to Gram-positive bacterium);GO:0071222(cellular response to lipopolysaccharide);GO:0009897(external side of plasma membrane);GO:0009986(cell surface);GO:0002250(adaptive immune response);GO:0050776(regulation of immune response);GO:0004872(receptor activity);GO:0005887(integral component of plasma membrane);GO:0007165(signal transduction);GO:0031295(T cell costimulation);GO:0034260(negative regulation of GTPase activity);GO:0042267(natural killer cell mediated cytotoxicity);GO:2000502(negative regulation of natural killer cell chemotaxis);GO:0006968(cellular defense response);GO:2000502(negative regulation of natural killer cell chemotaxis)","04650(Natural killer cell mediated cytotoxicity);05144(Malaria);04612(Antigen processing and presentation);05144(Malaria)","K06728;K06541","NA","killer cell lectin like receptor K1 [Source:HGNC Symbol;Acc:HGNC:18788];KLRC4-KLRK1 readthrough [Source:HGNC Symbol;Acc:HGNC:48357];killer cell lectin like receptor C4 [Source:HGNC Symbol;Acc:HGNC:6377]",{"v":18.3830784889732,"d":"18.38"},{"v":7.50973814352856,"d":"7.51"},{"v":2.44789873330199,"d":"2.45"},{"v":1.29154387666418,"d":"1.29"},{"v":0.0476172897332718,"d":"0.05"},{"v":0.657758046181462,"d":"0.66"},"up","yes"]
["MSTRG.9417","SLC11A1","MSTRG.9417.8;MSTRG.9417.7;ENST00000233202;ENST00000494322;ENST00000465984;ENST00000468221;MSTRG.9417.3;ENST00000354352;ENST00000539932;ENST00000469449;ENST00000469799;ENST00000473367;ENST00000468721;ENST00000492413;ENST00000475225;ENST00000490872;ENST00000483487;ENST00000460592;ENST00000490536","GO:0010628(positive regulation of gene expression);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005215(transporter activity);GO:0042803(protein homodimerization activity);GO:0006811(ion transport);GO:0005384(manganese ion transmembrane transporter activity);GO:0001818(negative regulation of cytokine production);GO:0001819(positive regulation of cytokine production);GO:0002309(T cell proliferation involved in immune response);GO:0002369(T cell cytokine production);GO:0002606(positive regulation of dendritic cell antigen processing and presentation);GO:0002827(positive regulation of T-helper 1 type immune response);GO:0006826(iron ion transport);GO:0006828(manganese ion transport);GO:0006879(cellular iron ion homeostasis);GO:0006909(phagocytosis);GO:0006954(inflammatory response);GO:0007035(vacuolar acidification);GO:0009617(response to bacterium);GO:0015707(nitrite transport);GO:0032147(activation of protein kinase activity);GO:0032496(response to lipopolysaccharide);GO:0032623(interleukin-2 production);GO:0032632(interleukin-3 production);GO:0032729(positive regulation of interferon-gamma production);GO:0034341(response to interferon-gamma);GO:0042060(wound healing);GO:0042116(macrophage activation);GO:0042742(defense response to bacterium);GO:0042832(defense response to protozoan);GO:0043091(L-arginine import);GO:0045342(MHC class II biosynthetic process);GO:0045730(respiratory burst);GO:0048002(antigen processing and presentation of peptide antigen);GO:0048255(mRNA stabilization);GO:0050766(positive regulation of phagocytosis);GO:0050829(defense response to Gram-negative bacterium);GO:0055072(iron ion homeostasis);GO:0060586(multicellular organismal iron ion homeostasis);GO:0070839(divalent metal ion export);GO:0071421(manganese ion transmembrane transport);GO:0005764(lysosome);GO:0005770(late endosome);GO:0010008(endosome membrane);GO:0030670(phagocytic vesicle membrane);GO:0005886(plasma membrane);GO:0005887(integral component of plasma membrane);GO:0043312(neutrophil degranulation);GO:0070821(tertiary granule membrane);GO:0019730(antimicrobial humoral response);GO:0101003(ficolin-1-rich granule membrane);GO:0045454(cell redox homeostasis);GO:0046915(transition metal ion transmembrane transporter activity);GO:0051139(metal ion:proton antiporter activity);GO:0006876(cellular cadmium ion homeostasis);GO:0070574(cadmium ion transmembrane transport);GO:0031902(late endosome membrane);GO:0006955(immune response);GO:0003674(molecular_function);GO:0005575(cellular_component);GO:0005575(cellular_component)","04142(Lysosome);04142(Lysosome)","K12347","NA","solute carrier family 11 member 1 [Source:HGNC Symbol;Acc:HGNC:10907]",{"v":7.88211153815122,"d":"7.88"},{"v":20.0041247992162,"d":"20.00"},{"v":0.394024313348618,"d":"0.39"},{"v":-1.34364344067463,"d":"-1.34"},{"v":0.0476303783649091,"d":"0.05"},{"v":0.657758046181462,"d":"0.66"},"down","yes"]
["MSTRG.7429","MPPE1","ENST00000344987;ENST00000588072;ENST00000592447;ENST00000592331;ENST00000589859;ENST00000587724;ENST00000589267;ENST00000588191;ENST00000592755;ENST00000586364;ENST00000591667;ENST00000589731;ENST00000590501;ENST00000592306;ENST00000586844;ENST00000496196;ENST00000592180;ENST00000590302;ENST00000589829;ENST00000593001;ENST00000587381;ENST00000588186;ENST00000592894;ENST00000317235;ENST00000588103;ENST00000586204;ENST00000592977;ENST00000317251;ENST00000588939;ENST00000309976","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005794(Golgi apparatus);GO:0046872(metal ion binding);GO:0005654(nucleoplasm);GO:0016787(hydrolase activity);GO:0006888(ER to Golgi vesicle-mediated transport);GO:0005515(protein binding);GO:0016192(vesicle-mediated transport);GO:0005783(endoplasmic reticulum);GO:0006506(GPI anchor biosynthetic process);GO:0005793(endoplasmic reticulum-Golgi intermediate compartment);GO:0033116(endoplasmic reticulum-Golgi intermediate compartment membrane);GO:0070971(endoplasmic reticulum exit site);GO:0034235(GPI anchor binding);GO:0005801(cis-Golgi network);GO:0030145(manganese ion binding);GO:0008081(phosphoric diester hydrolase activity);GO:0005737(cytoplasm);GO:0005737(cytoplasm)","NA","NA","NA","metallophosphoesterase 1 [Source:HGNC Symbol;Acc:HGNC:15988]",{"v":1.8990662068152,"d":"1.90"},{"v":4.84911669515072,"d":"4.85"},{"v":0.391631368392171,"d":"0.39"},{"v":-1.35243177016182,"d":"-1.35"},{"v":0.0479440532306409,"d":"0.05"},{"v":0.660442402007152,"d":"0.66"},"down","yes"]
["MSTRG.15349","CXCR3","ENST00000373693;ENST00000373691","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0004930(G-protein coupled receptor activity);GO:0007186(G-protein coupled receptor signaling pathway);GO:0005886(plasma membrane);GO:0004871(signal transducer activity);GO:0007165(signal transduction);GO:0006915(apoptotic process);GO:0004950(chemokine receptor activity);GO:0006935(chemotaxis);GO:0006954(inflammatory response);GO:0070098(chemokine-mediated signaling pathway);GO:0016494(C-X-C chemokine receptor activity);GO:0005887(integral component of plasma membrane);GO:0005737(cytoplasm);GO:0007155(cell adhesion);GO:0006928(movement of cell or subcellular component);GO:0001525(angiogenesis);GO:0007204(positive regulation of cytosolic calcium ion concentration);GO:0007166(cell surface receptor signaling pathway);GO:0019956(chemokine binding);GO:0002685(regulation of leukocyte migration);GO:0010818(T cell chemotaxis);GO:0019722(calcium-mediated signaling);GO:0009897(external side of plasma membrane);GO:0009986(cell surface);GO:0009986(cell surface)","04060(Cytokine-cytokine receptor interaction);04062(Chemokine signaling pathway);04062(Chemokine signaling pathway)","K04188","NA","C-X-C motif chemokine receptor 3 [Source:HGNC Symbol;Acc:HGNC:4540]",{"v":7.73282495289079,"d":"7.73"},{"v":3.149921374197,"d":"3.15"},{"v":2.45492634077639,"d":"2.45"},{"v":1.29567973761905,"d":"1.30"},{"v":0.0481748245463267,"d":"0.05"},{"v":0.660442402007152,"d":"0.66"},"up","yes"]
["ENSG00000112773","FAM46A","ENST00000369754;ENST00000412306;ENST00000320172;ENST00000369756","GO:0003723(RNA binding);GO:0005515(protein binding);GO:0010468(regulation of gene expression);GO:0030193(regulation of blood coagulation);GO:0030193(regulation of blood coagulation)","NA","NA","NA","family with sequence similarity 46 member A [Source:HGNC Symbol;Acc:HGNC:18345]",{"v":0.592316098463572,"d":"0.59"},{"v":1.51828150404758,"d":"1.52"},{"v":0.390122712345846,"d":"0.39"},{"v":-1.35800010258775,"d":"-1.36"},{"v":0.0481926093869382,"d":"0.05"},{"v":0.660442402007152,"d":"0.66"},"down","yes"]
["MSTRG.9832","NFATC2","ENST00000371564;ENST00000396009;ENST00000496054;ENST00000609943;ENST00000610033","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0006355(regulation of transcription, DNA-templated);GO:0006366(transcription from RNA polymerase II promoter);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0005515(protein binding);GO:0006974(cellular response to DNA damage stimulus);GO:0038095(Fc-epsilon receptor signaling pathway);GO:0030890(positive regulation of B cell proliferation);GO:0050853(B cell receptor signaling pathway);GO:0016477(cell migration);GO:0045893(positive regulation of transcription, DNA-templated);GO:0042493(response to drug);GO:0045589(regulation of regulatory T cell differentiation);GO:0000976(transcription regulatory region sequence-specific DNA binding);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:0000981(RNA polymerase II transcription factor activity, sequence-specific DNA binding);GO:0001077(transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0001078(transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0003682(chromatin binding);GO:0008134(transcription factor binding);GO:0043565(sequence-specific DNA binding);GO:0044212(transcription regulatory region DNA binding);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0001816(cytokine production);GO:0010628(positive regulation of gene expression);GO:0014904(myotube cell development);GO:0033173(calcineurin-NFAT signaling cascade);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:1901741(positive regulation of myoblast fusion);GO:0000790(nuclear chromatin);GO:0005667(transcription factor complex);GO:0030529(intracellular ribonucleoprotein complex);GO:0044798(nuclear transcription factor complex);GO:0044798(nuclear transcription factor complex)","04310(Wnt signaling pathway);04370(VEGF signaling pathway);04022(cGMP - PKG signaling pathway);04218(Cellular senescence);04650(Natural killer cell mediated cytotoxicity);04660(T cell receptor signaling pathway);04658(Th1 and Th2 cell differentiation);04659(Th17 cell differentiation);04662(B cell receptor signaling pathway);04921(Oxytocin signaling pathway);04360(Axon guidance);04380(Osteoclast differentiation);05166(HTLV-I infection);05161(Hepatitis B);05167(Kaposi's sarcoma-associated herpesvirus infection);05167(Kaposi's sarcoma-associated herpesvirus infection)","K17332","NA","nuclear factor of activated T-cells 2 [Source:HGNC Symbol;Acc:HGNC:7776]",{"v":10.4727665715665,"d":"10.47"},{"v":4.28822170359643,"d":"4.29"},{"v":2.44221667988463,"d":"2.44"},{"v":1.28819120570088,"d":"1.29"},{"v":0.04822551810506,"d":"0.05"},{"v":0.660442402007152,"d":"0.66"},"up","yes"]
["MSTRG.14917","ALAD","ENST00000409155;ENST00000468504;ENST00000464749;ENST00000448137;ENST00000482847;ENST00000445750;ENST00000482001;ENST00000452726;ENST00000494848","GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0003824(catalytic activity);GO:0016829(lyase activity);GO:0008270(zinc ion binding);GO:0008152(metabolic process);GO:0006783(heme biosynthetic process);GO:0005576(extracellular region);GO:0033014(tetrapyrrole biosynthetic process);GO:0004655(porphobilinogen synthase activity);GO:0042802(identical protein binding);GO:1904854(proteasome core complex binding);GO:0001666(response to hypoxia);GO:0006779(porphyrin-containing compound biosynthetic process);GO:0006979(response to oxidative stress);GO:0007584(response to nutrient);GO:0009635(response to herbicide);GO:0009636(response to toxic substance);GO:0009725(response to hormone);GO:0010033(response to organic substance);GO:0010035(response to inorganic substance);GO:0010038(response to metal ion);GO:0010039(response to iron ion);GO:0010043(response to zinc ion);GO:0010044(response to aluminum ion);GO:0010212(response to ionizing radiation);GO:0010266(response to vitamin B1);GO:0010269(response to selenium ion);GO:0010288(response to lead ion);GO:0014070(response to organic cyclic compound);GO:0014823(response to activity);GO:0031667(response to nutrient levels);GO:0032025(response to cobalt ion);GO:0032496(response to lipopolysaccharide);GO:0033197(response to vitamin E);GO:0033273(response to vitamin);GO:0042493(response to drug);GO:0043200(response to amino acid);GO:0045471(response to ethanol);GO:0046685(response to arsenic-containing substance);GO:0046686(response to cadmium ion);GO:0046689(response to mercury ion);GO:0051384(response to glucocorticoid);GO:0051597(response to methylmercury);GO:0070541(response to platinum ion);GO:0070542(response to fatty acid);GO:0071284(cellular response to lead ion);GO:0071353(cellular response to interleukin-4);GO:0005615(extracellular space);GO:0005829(cytosol);GO:0005839(proteasome core complex);GO:0006782(protoporphyrinogen IX biosynthetic process);GO:0070062(extracellular exosome);GO:0043312(neutrophil degranulation);GO:0034774(secretory granule lumen);GO:1904813(ficolin-1-rich granule lumen);GO:0051260(protein homooligomerization);GO:1901799(negative regulation of proteasomal protein catabolic process);GO:1901799(negative regulation of proteasomal protein catabolic process)","00860(Porphyrin and chlorophyll metabolism);00860(Porphyrin and chlorophyll metabolism)","K01698","EC:4.2.1.24","aminolevulinate dehydratase [Source:HGNC Symbol;Acc:HGNC:395]",{"v":2.3830972815573,"d":"2.38"},{"v":6.07683700521774,"d":"6.08"},{"v":0.392160803311181,"d":"0.39"},{"v":-1.35048275031735,"d":"-1.35"},{"v":0.0482823844657213,"d":"0.05"},{"v":0.660442402007152,"d":"0.66"},"down","yes"]
["MSTRG.14952","NEK6","ENST00000394199;ENST00000320246;ENST00000423785;ENST00000444973;ENST00000545174;ENST00000546191;ENST00000539416;ENST00000373600;ENST00000373596;ENST00000454453;MSTRG.14952.8;ENST00000422297;ENST00000425237","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016607(nuclear speck);GO:0043231(intracellular membrane-bounded organelle);GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0051301(cell division);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0004871(signal transducer activity);GO:0007049(cell cycle);GO:0006915(apoptotic process);GO:0000287(magnesium ion binding);GO:0005815(microtubule organizing center);GO:0005874(microtubule);GO:0007165(signal transduction);GO:0000922(spindle pole);GO:0005813(centrosome);GO:0007059(chromosome segregation);GO:0019901(protein kinase binding);GO:0043234(protein complex);GO:0031625(ubiquitin protein ligase binding);GO:0043123(positive regulation of I-kappaB kinase/NF-kappaB signaling);GO:0007346(regulation of mitotic cell cycle);GO:2000772(regulation of cellular senescence);GO:0046777(protein autophosphorylation);GO:0000910(cytokinesis);GO:0019894(kinesin binding);GO:0031572(G2 DNA damage checkpoint);GO:0051225(spindle assembly);GO:0007077(mitotic nuclear envelope disassembly);GO:0001222(transcription corepressor binding);GO:0018105(peptidyl-serine phosphorylation);GO:0033613(activating transcription factor binding);GO:0030071(regulation of mitotic metaphase/anaphase transition);GO:0030071(regulation of mitotic metaphase/anaphase transition)","NA","NA","NA","NIMA related kinase 6 [Source:HGNC Symbol;Acc:HGNC:7749]",{"v":2.8339570469697,"d":"2.83"},{"v":7.20099537922078,"d":"7.20"},{"v":0.393550738158696,"d":"0.39"},{"v":-1.34537844906278,"d":"-1.35"},{"v":0.0482833146388216,"d":"0.05"},{"v":0.660442402007152,"d":"0.66"},"down","yes"]
["MSTRG.10181","AC245452.2","ENST00000435222","NA","NA","NA","NA",null,{"v":6.021599,"d":"6.02"},{"v":15.495562,"d":"15.50"},{"v":0.388601523455555,"d":"0.39"},{"v":-1.36363653807768,"d":"-1.36"},{"v":0.0483053591396001,"d":"0.05"},{"v":0.660442402007152,"d":"0.66"},"down","yes"]
["ENSG00000164603","BMT2","ENST00000297145;ENST00000485446;ENST00000432572","GO:0008168(methyltransferase activity);GO:0016740(transferase activity);GO:0032259(methylation);GO:0005730(nucleolus);GO:0031167(rRNA methylation);GO:0016433(rRNA (adenine) methyltransferase activity);GO:0016433(rRNA (adenine) methyltransferase activity)","NA","NA","NA","base methyltransferase of 25S rRNA 2 homolog [Source:HGNC Symbol;Acc:HGNC:26475]",{"v":0.810366126631223,"d":"0.81"},{"v":2.07497471048816,"d":"2.07"},{"v":0.390542652175542,"d":"0.39"},{"v":-1.35644797745003,"d":"-1.36"},{"v":0.0483066007149912,"d":"0.05"},{"v":0.660442402007152,"d":"0.66"},"down","yes"]
["ENSG00000257923","CUX1","ENST00000292538;ENST00000437600;ENST00000547394;ENST00000360264;ENST00000558469;ENST00000465461;ENST00000622516;ENST00000425244;ENST00000485792;ENST00000558836;ENST00000560541;ENST00000292535;ENST00000487284;ENST00000546411;ENST00000549414","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005794(Golgi apparatus);GO:0005654(nucleoplasm);GO:0000139(Golgi membrane);GO:0006891(intra-Golgi vesicle-mediated transport);GO:0030173(integral component of Golgi membrane);GO:0005634(nucleus);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0018108(peptidyl-tyrosine phosphorylation);GO:0043565(sequence-specific DNA binding);GO:0007275(multicellular organism development);GO:0005829(cytosol);GO:0000977(RNA polymerase II regulatory region sequence-specific DNA binding);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0004713(protein tyrosine kinase activity);GO:0048193(Golgi vesicle transport);GO:0050775(positive regulation of dendrite morphogenesis);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0030674(protein binding, bridging);GO:0000301(retrograde transport, vesicle recycling within Golgi);GO:0000301(retrograde transport, vesicle recycling within Golgi)","NA","NA","NA","cut like homeobox 1 [Source:HGNC Symbol;Acc:HGNC:2557]",{"v":1.41928621503261,"d":"1.42"},{"v":3.5995800639195,"d":"3.60"},{"v":0.394292164594106,"d":"0.39"},{"v":-1.34266305350971,"d":"-1.34"},{"v":0.0483254572268556,"d":"0.05"},{"v":0.660442402007152,"d":"0.66"},"down","yes"]
["ENSG00000143458","GABPB2","ENST00000368918;ENST00000368916;ENST00000489549;ENST00000486076;ENST00000462520","GO:0005634(nucleus);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0005515(protein binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0046982(protein heterodimerization activity);GO:0044212(transcription regulatory region DNA binding);GO:0042803(protein homodimerization activity);GO:0042803(protein homodimerization activity)","NA","NA","NA","GA binding protein transcription factor beta subunit 2 [Source:HGNC Symbol;Acc:HGNC:28441]",{"v":2.16681503199478,"d":"2.17"},{"v":0.884305474371531,"d":"0.88"},{"v":2.45030150190433,"d":"2.45"},{"v":1.29295927924414,"d":"1.29"},{"v":0.0484475033941263,"d":"0.05"},{"v":0.660442402007152,"d":"0.66"},"up","yes"]
["MSTRG.15209","AC004552.1","ENST00000419089","NA","NA","NA","NA",null,{"v":15.433908,"d":"15.43"},{"v":6.199854,"d":"6.20"},{"v":2.48939862132237,"d":"2.49"},{"v":1.31579726405086,"d":"1.32"},{"v":0.0484947543038483,"d":"0.05"},{"v":0.660442402007152,"d":"0.66"},"up","yes"]
["MSTRG.15429","LAMP2","ENST00000371335;ENST00000200639;ENST00000434600;ENST00000486593","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005765(lysosomal membrane);GO:0005886(plasma membrane);GO:0005615(extracellular space);GO:0006914(autophagy);GO:0031410(cytoplasmic vesicle);GO:0005764(lysosome);GO:0005768(endosome);GO:0070062(extracellular exosome);GO:0050821(protein stabilization);GO:0000421(autophagosome membrane);GO:0009267(cellular response to starvation);GO:0010008(endosome membrane);GO:0043312(neutrophil degranulation);GO:0006605(protein targeting);GO:0019899(enzyme binding);GO:0002576(platelet degranulation);GO:0031088(platelet dense granule membrane);GO:0005515(protein binding);GO:0035577(azurophil granule membrane);GO:0101003(ficolin-1-rich granule membrane);GO:0031647(regulation of protein stability);GO:0097352(autophagosome maturation);GO:0044754(autolysosome);GO:0043202(lysosomal lumen);GO:0005770(late endosome);GO:0098857(membrane microdomain);GO:0019904(protein domain specific binding);GO:0017038(protein import);GO:0046716(muscle cell cellular homeostasis);GO:0061684(chaperone-mediated autophagy);GO:0061740(protein targeting to lysosome involved in chaperone-mediated autophagy);GO:1905146(lysosomal protein catabolic process);GO:0030670(phagocytic vesicle membrane);GO:0031902(late endosome membrane);GO:0097637(integral component of autophagosome membrane);GO:0097637(integral component of autophagosome membrane)","04145(Phagosome);04142(Lysosome);04140(Autophagy - animal);05152(Tuberculosis);05152(Tuberculosis)","K06528","NA","lysosomal associated membrane protein 2 [Source:HGNC Symbol;Acc:HGNC:6501]",{"v":9.35037477759682,"d":"9.35"},{"v":23.6363340832429,"d":"23.64"},{"v":0.395593273672071,"d":"0.40"},{"v":-1.33791019892796,"d":"-1.34"},{"v":0.0485084844332098,"d":"0.05"},{"v":0.660442402007152,"d":"0.66"},"down","yes"]
["ENSG00000153790","C7orf31","ENST00000283905;ENST00000443822;ENST00000444434;ENST00000409280;ENST00000415598","GO:0005737(cytoplasm);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0005813(centrosome);GO:0005815(microtubule organizing center);GO:0005815(microtubule organizing center)","NA","NA","NA","chromosome 7 open reading frame 31 [Source:HGNC Symbol;Acc:HGNC:21722]",{"v":1.36333291425593,"d":"1.36"},{"v":0.545237697159239,"d":"0.55"},{"v":2.50043773818112,"d":"2.50"},{"v":1.32218068185586,"d":"1.32"},{"v":0.0485377450403861,"d":"0.05"},{"v":0.660442402007152,"d":"0.66"},"up","yes"]
["MSTRG.13917","IFRD1;LSMEM1","ENST00000005558;ENST00000621379;ENST00000312849;ENST00000429071;ENST00000471030;ENST00000432734;ENST00000486688;ENST00000486022;ENST00000470441;ENST00000421296;ENST00000462155;ENST00000455302;ENST00000443101;ENST00000466459;ENST00000535603;ENST00000476927;ENST00000445335;ENST00000403825;ENST00000489994;ENST00000439068","GO:0007275(multicellular organism development);GO:0030154(cell differentiation);GO:0007518(myoblast fate determination);GO:0014706(striated muscle tissue development);GO:0030517(negative regulation of axon extension);GO:0042692(muscle cell differentiation);GO:0043403(skeletal muscle tissue regeneration);GO:0048671(negative regulation of collateral sprouting);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005829(cytosol);GO:0005515(protein binding);GO:0005515(protein binding)","NA","NA","NA","interferon related developmental regulator 1 [Source:HGNC Symbol;Acc:HGNC:5456];leucine rich single-pass membrane protein 1 [Source:HGNC Symbol;Acc:HGNC:22036]",{"v":1.24733486930673,"d":"1.25"},{"v":3.17014201682789,"d":"3.17"},{"v":0.393463404063784,"d":"0.39"},{"v":-1.34569863763218,"d":"-1.35"},{"v":0.0487212401322731,"d":"0.05"},{"v":0.661594585635785,"d":"0.66"},"down","yes"]
["ENSG00000177426","TGIF1","ENST00000343820;ENST00000405385;ENST00000618001;ENST00000401449;ENST00000551333;ENST00000552383;ENST00000549780;ENST00000407501;ENST00000577543;ENST00000472042;ENST00000551402;ENST00000549253;ENST00000330513;ENST00000400167;ENST00000546979;ENST00000551541","GO:0005634(nucleus);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0005654(nucleoplasm);GO:0006351(transcription, DNA-templated);GO:0005515(protein binding);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:0001078(transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0007275(multicellular organism development);GO:0003714(transcription corepressor activity);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0070410(co-SMAD binding);GO:0010629(negative regulation of gene expression);GO:0042493(response to drug);GO:0071363(cellular response to growth factor stimulus);GO:0071363(cellular response to growth factor stimulus)","04350(TGF-beta signaling pathway);04350(TGF-beta signaling pathway)","K19383","NA","TGFB induced factor homeobox 1 [Source:HGNC Symbol;Acc:HGNC:11776]",{"v":1.45414200170275,"d":"1.45"},{"v":0.584093339333495,"d":"0.58"},{"v":2.489571278731,"d":"2.49"},{"v":1.31589732169021,"d":"1.32"},{"v":0.0487414248478413,"d":"0.05"},{"v":0.661594585635785,"d":"0.66"},"up","yes"]
["MSTRG.13288","SGK1","ENST00000528577;MSTRG.13288.5;ENST00000474427;ENST00000485771;ENST00000237305;ENST00000533224;ENST00000532021;ENST00000490149;ENST00000484353;ENST00000525877;ENST00000475882;ENST00000367857;ENST00000531782;ENST00000534658;ENST00000477460;ENST00000367855;ENST00000475719;ENST00000473704;ENST00000524929;ENST00000524764;ENST00000472859;ENST00000413996;ENST00000460769;ENST00000532856;ENST00000530421;ENST00000524387;ENST00000367858;ENST00000525700","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016607(nuclear speck);GO:0016020(membrane);GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0005829(cytosol);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005739(mitochondrion);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0006915(apoptotic process);GO:0035556(intracellular signal transduction);GO:0034220(ion transmembrane transport);GO:0004712(protein serine/threonine/tyrosine kinase activity);GO:0005246(calcium channel regulator activity);GO:0015459(potassium channel regulator activity);GO:0017080(sodium channel regulator activity);GO:0017081(chloride channel regulator activity);GO:0001558(regulation of cell growth);GO:0006814(sodium ion transport);GO:0006950(response to stress);GO:0006974(cellular response to DNA damage stimulus);GO:0007616(long-term memory);GO:0008217(regulation of blood pressure);GO:0018105(peptidyl-serine phosphorylation);GO:0030334(regulation of cell migration);GO:0032411(positive regulation of transporter activity);GO:0042127(regulation of cell proliferation);GO:0042981(regulation of apoptotic process);GO:0048812(neuron projection morphogenesis);GO:0050790(regulation of catalytic activity);GO:0051090(regulation of sequence-specific DNA binding transcription factor activity);GO:0060453(regulation of gastric acid secretion);GO:0070294(renal sodium ion absorption);GO:0035091(phosphatidylinositol binding);GO:0035091(phosphatidylinositol binding)","04068(FoxO signaling pathway);04151(PI3K-Akt signaling pathway);04150(mTOR signaling pathway);04960(Aldosterone-regulated sodium reabsorption);04960(Aldosterone-regulated sodium reabsorption)","K13302","EC:2.7.11.1","serum/glucocorticoid regulated kinase 1 [Source:HGNC Symbol;Acc:HGNC:10810]",{"v":3.28883686234494,"d":"3.29"},{"v":8.31466866936775,"d":"8.31"},{"v":0.395546352251102,"d":"0.40"},{"v":-1.33808132751059,"d":"-1.34"},{"v":0.0487872439831072,"d":"0.05"},{"v":0.661594585635785,"d":"0.66"},"down","yes"]
["ENSG00000101384","JAG1","ENST00000254958;ENST00000620743;ENST00000423891;ENST00000488480;ENST00000617357;ENST00000617965","GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005509(calcium ion binding);GO:0008083(growth factor activity);GO:0007275(multicellular organism development);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0005112(Notch binding);GO:0007399(nervous system development);GO:0007219(Notch signaling pathway);GO:0007154(cell communication);GO:0005886(plasma membrane);GO:0005887(integral component of plasma membrane);GO:0005912(adherens junction);GO:0002456(T cell mediated immunity);GO:0030334(regulation of cell migration);GO:0042127(regulation of cell proliferation);GO:0016324(apical plasma membrane);GO:0001525(angiogenesis);GO:0001709(cell fate determination);GO:0007220(Notch receptor processing);GO:0030097(hemopoiesis);GO:0045747(positive regulation of Notch signaling pathway);GO:0072006(nephron development);GO:0097150(neuronal stem cell population maintenance);GO:0072015(glomerular visceral epithelial cell development);GO:0030216(keratinocyte differentiation);GO:0005198(structural molecule activity);GO:0045446(endothelial cell differentiation);GO:0003184(pulmonary valve morphogenesis);GO:2000737(negative regulation of stem cell differentiation);GO:0061314(Notch signaling involved in heart development);GO:0060411(cardiac septum morphogenesis);GO:0045445(myoblast differentiation);GO:0005543(phospholipid binding);GO:0035909(aorta morphogenesis);GO:0003215(cardiac right ventricle morphogenesis);GO:0061309(cardiac neural crest cell development involved in outflow tract morphogenesis);GO:0001974(blood vessel remodeling);GO:0002011(morphogenesis of an epithelial sheet);GO:0009887(animal organ morphogenesis);GO:0032495(response to muramyl dipeptide);GO:0042491(auditory receptor cell differentiation);GO:0043010(camera-type eye development);GO:0045596(negative regulation of cell differentiation);GO:0045599(negative regulation of fat cell differentiation);GO:0045602(negative regulation of endothelial cell differentiation);GO:0045639(positive regulation of myeloid cell differentiation);GO:0045665(negative regulation of neuron differentiation);GO:0045669(positive regulation of osteoblast differentiation);GO:0048839(inner ear development);GO:0061073(ciliary body morphogenesis);GO:0061156(pulmonary artery morphogenesis);GO:0061444(endocardial cushion cell development);GO:0072017(distal tubule development);GO:0072070(loop of Henle development);GO:0045177(apical part of cell);GO:0045177(apical part of cell)","04330(Notch signaling pathway);04371(Apelin signaling pathway);04668(TNF signaling pathway);04658(Th1 and Th2 cell differentiation);05200(Pathways in cancer);05224(Breast cancer);05165(Human papillomavirus infection);01522(Endocrine resistance);01522(Endocrine resistance)","K06052","NA","jagged 1 [Source:HGNC Symbol;Acc:HGNC:6188]",{"v":0.111776091985001,"d":"0.11"},{"v":0.300724249355519,"d":"0.30"},{"v":0.371689653310459,"d":"0.37"},{"v":-1.42782956629342,"d":"-1.43"},{"v":0.0488816809764726,"d":"0.05"},{"v":0.662129586410217,"d":"0.66"},"down","yes"]
["ENSG00000101751","POLI","ENST00000581950;ENST00000579434;ENST00000580880;ENST00000579823;ENST00000579534;ENST00000580905;ENST00000577361;ENST00000582366;ENST00000577612;ENST00000577971;ENST00000585023;ENST00000583576;ENST00000577727","GO:0005634(nucleus);GO:0016607(nuclear speck);GO:0046872(metal ion binding);GO:0016740(transferase activity);GO:0003677(DNA binding);GO:0003684(damaged DNA binding);GO:0006281(DNA repair);GO:0005515(protein binding);GO:0006974(cellular response to DNA damage stimulus);GO:0016779(nucleotidyltransferase activity);GO:0003887(DNA-directed DNA polymerase activity);GO:0006260(DNA replication);GO:0000932(P-body);GO:0005654(nucleoplasm);GO:0071897(DNA biosynthetic process);GO:0019985(translesion synthesis);GO:0005622(intracellular);GO:0042276(error-prone translesion synthesis);GO:0042276(error-prone translesion synthesis)","03460(Fanconi anemia pathway);03460(Fanconi anemia pathway)","K03510","EC:2.7.7.7","DNA polymerase iota [Source:HGNC Symbol;Acc:HGNC:9182]",{"v":0.093131088691796,"d":"0.09"},{"v":0.249547797487066,"d":"0.25"},{"v":0.373199401596093,"d":"0.37"},{"v":-1.42198142197486,"d":"-1.42"},{"v":0.0490438164692579,"d":"0.05"},{"v":0.663530839514584,"d":"0.66"},"down","yes"]
["MSTRG.6690","SLFN5","ENST00000299977;ENST00000542451;ENST00000592325","GO:0005634(nucleus);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0030154(cell differentiation);GO:0030154(cell differentiation)","NA","NA","NA","schlafen family member 5 [Source:HGNC Symbol;Acc:HGNC:28286]",{"v":15.43722728378,"d":"15.44"},{"v":6.35139767877486,"d":"6.35"},{"v":2.4305244395841,"d":"2.43"},{"v":1.28126764089033,"d":"1.28"},{"v":0.0490953311748459,"d":"0.05"},{"v":0.663530839514584,"d":"0.66"},"up","yes"]
["MSTRG.7015","SAMD14","ENST00000330175;ENST00000285206;ENST00000507043;ENST00000573376;ENST00000508892;ENST00000515816;ENST00000503734;ENST00000511964","NA","NA","NA","NA","sterile alpha motif domain containing 14 [Source:HGNC Symbol;Acc:HGNC:27312]",{"v":0.537866560433295,"d":"0.54"},{"v":0.214965922462942,"d":"0.21"},{"v":2.5021015157694,"d":"2.50"},{"v":1.32314032400654,"d":"1.32"},{"v":0.0492601943044437,"d":"0.05"},{"v":0.66501262310999,"d":"0.67"},"up","yes"]
["ENSG00000127554","GFER","ENST00000248114;ENST00000561710;ENST00000569451;ENST00000565658;ENST00000567719","GO:0005829(cytosol);GO:0005739(mitochondrion);GO:0005737(cytoplasm);GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0008083(growth factor activity);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0050660(flavin adenine dinucleotide binding);GO:0005758(mitochondrial intermembrane space);GO:0016972(thiol oxidase activity);GO:0015035(protein disulfide oxidoreductase activity);GO:0016971(flavin-linked sulfhydryl oxidase activity);GO:0001889(liver development);GO:0001889(liver development)","NA","NA","NA","growth factor, augmenter of liver regeneration [Source:HGNC Symbol;Acc:HGNC:4236]",{"v":2.42454551991068,"d":"2.42"},{"v":0.976545054707853,"d":"0.98"},{"v":2.48277896470022,"d":"2.48"},{"v":1.31195582787591,"d":"1.31"},{"v":0.0494623995458508,"d":"0.05"},{"v":0.666673257877872,"d":"0.67"},"up","yes"]
["MSTRG.2788","PICALM","MSTRG.2788.3;MSTRG.2788.1;ENST00000356360;MSTRG.2788.2;ENST00000526907;ENST00000526548;ENST00000532317;ENST00000529016;ENST00000534375;ENST00000533350;ENST00000528411;ENST00000630913;ENST00000532603;ENST00000530692;ENST00000531771;ENST00000528398;ENST00000526033;ENST00000529760;ENST00000528256;ENST00000525162;ENST00000531930;ENST00000534412;ENST00000393346;ENST00000532041;ENST00000530542;ENST00000531558","GO:0048471(perinuclear region of cytoplasm);GO:0005634(nucleus);GO:0016020(membrane);GO:0043231(intracellular membrane-bounded organelle);GO:0006897(endocytosis);GO:0005794(Golgi apparatus);GO:0031410(cytoplasmic vesicle);GO:0005543(phospholipid binding);GO:0005545(1-phosphatidylinositol binding);GO:0030276(clathrin binding);GO:0048268(clathrin coat assembly);GO:0030136(clathrin-coated vesicle);GO:0005905(clathrin-coated pit);GO:0005515(protein binding);GO:0005829(cytosol);GO:0045296(cadherin binding);GO:0061024(membrane organization);GO:0016192(vesicle-mediated transport);GO:0045893(positive regulation of transcription, DNA-templated);GO:0006461(protein complex assembly);GO:0042734(presynaptic membrane);GO:0030132(clathrin coat of coated pit);GO:0006898(receptor-mediated endocytosis);GO:0030122(AP-2 adaptor complex);GO:0016197(endosomal transport);GO:0050750(low-density lipoprotein particle receptor binding);GO:0032050(clathrin heavy chain binding);GO:0032880(regulation of protein localization);GO:0048261(negative regulation of receptor-mediated endocytosis);GO:0045211(postsynaptic membrane);GO:1901216(positive regulation of neuron death);GO:1902004(positive regulation of amyloid-beta formation);GO:0097418(neurofibrillary tangle);GO:0045056(transcytosis);GO:0031623(receptor internalization);GO:0030100(regulation of endocytosis);GO:0072583(clathrin-dependent endocytosis);GO:0005769(early endosome);GO:0017137(Rab GTPase binding);GO:0035615(clathrin adaptor activity);GO:0008283(cell proliferation);GO:0010629(negative regulation of gene expression);GO:0016188(synaptic vesicle maturation);GO:0035459(cargo loading into vesicle);GO:0043547(positive regulation of GTPase activity);GO:0055072(iron ion homeostasis);GO:0098711(iron ion import across plasma membrane);GO:1902959(regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process);GO:1902961(positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process);GO:1902963(negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process);GO:0009986(cell surface);GO:0031982(vesicle);GO:0043025(neuronal cell body);GO:0070381(endosome to plasma membrane transport vesicle);GO:0007409(axonogenesis);GO:0007611(learning or memory);GO:0030097(hemopoiesis);GO:0048813(dendrite morphogenesis);GO:0090647(modulation of age-related behavioral decline);GO:1900223(positive regulation of amyloid-beta clearance);GO:0005622(intracellular);GO:0005622(intracellular)","NA","NA","NA","phosphatidylinositol binding clathrin assembly protein [Source:HGNC Symbol;Acc:HGNC:15514]",{"v":16.4910997948556,"d":"16.49"},{"v":41.5292567726053,"d":"41.53"},{"v":0.397095952984498,"d":"0.40"},{"v":-1.33244043722052,"d":"-1.33"},{"v":0.0494939289605396,"d":"0.05"},{"v":0.666673257877872,"d":"0.67"},"down","yes"]
["MSTRG.1461",null,"MSTRG.1461.1","NA","NA","NA","NA",null,{"v":6.142243,"d":"6.14"},{"v":2.462964,"d":"2.46"},{"v":2.49384197251767,"d":"2.49"},{"v":1.31837004869271,"d":"1.32"},{"v":0.0498061213328167,"d":"0.05"},{"v":0.668316090499971,"d":"0.67"},"up","yes"]
["MSTRG.6678","MYO1D","ENST00000318217;ENST00000577352;ENST00000582217;ENST00000579584;ENST00000580538","GO:0005829(cytosol);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0003774(motor activity);GO:0016459(myosin complex);GO:0003779(actin binding);GO:0031410(cytoplasmic vesicle);GO:0005516(calmodulin binding);GO:0005768(endosome);GO:0030424(axon);GO:0051015(actin filament binding);GO:0070062(extracellular exosome);GO:0016323(basolateral plasma membrane);GO:0010923(negative regulation of phosphatase activity);GO:0005903(brush border);GO:0043005(neuron projection);GO:0019904(protein domain specific binding);GO:0043025(neuronal cell body);GO:0097440(apical dendrite);GO:0000146(microfilament motor activity);GO:0030898(actin-dependent ATPase activity);GO:0048306(calcium-dependent protein binding);GO:0030900(forebrain development);GO:0051641(cellular localization);GO:0061502(early endosome to recycling endosome transport);GO:0005790(smooth endoplasmic reticulum);GO:0030673(axolemma);GO:0043209(myelin sheath);GO:0044853(plasma membrane raft);GO:0044853(plasma membrane raft)","NA","NA","NA","myosin ID [Source:HGNC Symbol;Acc:HGNC:7598]",{"v":0.817454371519297,"d":"0.82"},{"v":0.332074683683439,"d":"0.33"},{"v":2.46165821029152,"d":"2.46"},{"v":1.29963046428051,"d":"1.30"},{"v":0.049818373409253,"d":"0.05"},{"v":0.668316090499971,"d":"0.67"},"up","yes"]
["MSTRG.13443","MAFK","ENST00000343242;ENST00000403150;ENST00000406174","GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0005515(protein binding);GO:0000976(transcription regulatory region sequence-specific DNA binding);GO:0001221(transcription cofactor binding);GO:0071535(RING-like zinc finger domain binding);GO:0007399(nervous system development);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0043565(sequence-specific DNA binding);GO:0001227(transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding);GO:0007596(blood coagulation);GO:0007596(blood coagulation)","NA","NA","NA","MAF bZIP transcription factor K [Source:HGNC Symbol;Acc:HGNC:6782]",{"v":4.59498126783311,"d":"4.59"},{"v":1.8833232833109,"d":"1.88"},{"v":2.43982608219821,"d":"2.44"},{"v":1.28677831201244,"d":"1.29"},{"v":0.0498661245726631,"d":"0.05"},{"v":0.668316090499971,"d":"0.67"},"up","yes"]
["MSTRG.15171","TLR8","ENST00000311912;MSTRG.15171.2;ENST00000218032","GO:0003723(RNA binding);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0003677(DNA binding);GO:0007165(signal transduction);GO:0003727(single-stranded RNA binding);GO:0006954(inflammatory response);GO:0003725(double-stranded RNA binding);GO:0051607(defense response to virus);GO:0002376(immune system process);GO:0002755(MyD88-dependent toll-like receptor signaling pathway);GO:0045087(innate immune response);GO:0050707(regulation of cytokine secretion);GO:0005887(integral component of plasma membrane);GO:0005789(endoplasmic reticulum membrane);GO:0010008(endosome membrane);GO:0004872(receptor activity);GO:0009615(response to virus);GO:0045089(positive regulation of innate immune response);GO:0002224(toll-like receptor signaling pathway);GO:0045416(positive regulation of interleukin-8 biosynthetic process);GO:0071260(cellular response to mechanical stimulus);GO:0000139(Golgi membrane);GO:0007249(I-kappaB kinase/NF-kappaB signaling);GO:0045078(positive regulation of interferon-gamma biosynthetic process);GO:0045356(positive regulation of interferon-alpha biosynthetic process);GO:0045359(positive regulation of interferon-beta biosynthetic process);GO:0036020(endolysosome membrane);GO:0034162(toll-like receptor 9 signaling pathway);GO:2000778(positive regulation of interleukin-6 secretion);GO:0016064(immunoglobulin mediated immune response);GO:0009897(external side of plasma membrane);GO:0034158(toll-like receptor 8 signaling pathway);GO:0050718(positive regulation of interleukin-1 beta secretion);GO:2001183(negative regulation of interleukin-12 secretion);GO:0008144(drug binding);GO:0001774(microglial cell activation);GO:0001932(regulation of protein phosphorylation);GO:0001932(regulation of protein phosphorylation)","04620(Toll-like receptor signaling pathway);04620(Toll-like receptor signaling pathway)","K10170","NA","toll like receptor 8 [Source:HGNC Symbol;Acc:HGNC:15632]",{"v":6.82448250895693,"d":"6.82"},{"v":17.1529197935459,"d":"17.15"},{"v":0.397861273246597,"d":"0.40"},{"v":-1.32966261710265,"d":"-1.33"},{"v":0.0498857613562196,"d":"0.05"},{"v":0.668316090499971,"d":"0.67"},"down","yes"]
["MSTRG.3992","RUBCNL","ENST00000378787;ENST00000429979;ENST00000439642;ENST00000487195;ENST00000378781;ENST00000389908;ENST00000378784;ENST00000631139;ENST00000378797","NA","NA","NA","NA","RUN and cysteine rich domain containing beclin 1 interacting protein like [Source:HGNC Symbol;Acc:HGNC:20420]",{"v":2.61140255741196,"d":"2.61"},{"v":6.5783154045864,"d":"6.58"},{"v":0.396971321197413,"d":"0.40"},{"v":-1.33289330983846,"d":"-1.33"},{"v":0.0498953258122539,"d":"0.05"},{"v":0.668316090499971,"d":"0.67"},"down","yes"]
["ENSG00000165046","LETM2","ENST00000518883;ENST00000519476;ENST00000527334;ENST00000379957;ENST00000526075;ENST00000527175;ENST00000523983;ENST00000297720;ENST00000527710;ENST00000523268;ENST00000524874;ENST00000530448","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005743(mitochondrial inner membrane);GO:0005739(mitochondrion);GO:0043022(ribosome binding);GO:0006875(cellular metal ion homeostasis);GO:0003824(catalytic activity);GO:0003824(catalytic activity)","NA","NA","NA","leucine zipper and EF-hand containing transmembrane protein 2 [Source:HGNC Symbol;Acc:HGNC:14648]",{"v":0.388880091756624,"d":"0.39"},{"v":0.994632679260713,"d":"0.99"},{"v":0.390978599301271,"d":"0.39"},{"v":-1.35483845289666,"d":"-1.35"},{"v":0.0499488856875912,"d":"0.05"},{"v":0.668316090499971,"d":"0.67"},"down","yes"]
["MSTRG.13717","NCF1","ENST00000486097;ENST00000289473;MSTRG.13717.2;ENST00000488197;ENST00000398421;ENST00000443956;ENST00000433458;ENST00000438106;ENST00000464878;ENST00000449343;ENST00000442021;ENST00000455062","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005829(cytosol);GO:0055114(oxidation-reduction process);GO:0005515(protein binding);GO:0035091(phosphatidylinositol binding);GO:0008289(lipid binding);GO:0016175(superoxide-generating NADPH oxidase activity);GO:0016176(superoxide-generating NADPH oxidase activator activity);GO:0071800(podosome assembly);GO:0002102(podosome);GO:0002479(antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent);GO:0019898(extrinsic component of membrane);GO:0043325(phosphatidylinositol-3,4-bisphosphate binding);GO:0006612(protein targeting to membrane);GO:0045087(innate immune response);GO:0048010(vascular endothelial growth factor receptor signaling pathway);GO:0005886(plasma membrane);GO:0009055(electron carrier activity);GO:0034599(cellular response to oxidative stress);GO:0034614(cellular response to reactive oxygen species);GO:0045893(positive regulation of transcription, DNA-templated);GO:0071276(cellular response to cadmium ion);GO:0017124(SH3 domain binding);GO:0006968(cellular defense response);GO:0006801(superoxide metabolic process);GO:0042554(superoxide anion generation);GO:0045454(cell redox homeostasis);GO:0045730(respiratory burst);GO:0043020(NADPH oxidase complex);GO:0006915(apoptotic process);GO:0014068(positive regulation of phosphatidylinositol 3-kinase signaling);GO:0045741(positive regulation of epidermal growth factor-activated receptor activity);GO:0046330(positive regulation of JNK cascade);GO:1900745(positive regulation of p38MAPK cascade);GO:0005791(rough endoplasmic reticulum);GO:0005794(Golgi apparatus);GO:0030425(dendrite);GO:0032010(phagolysosome);GO:0043025(neuronal cell body);GO:0043025(neuronal cell body)","04145(Phagosome);04666(Fc gamma R-mediated phagocytosis);04670(Leukocyte transendothelial migration);04062(Chemokine signaling pathway);04380(Osteoclast differentiation);05418(Fluid shear stress and atherosclerosis);05140(Leishmaniasis);05140(Leishmaniasis)","K08011","NA","neutrophil cytosolic factor 1 [Source:HGNC Symbol;Acc:HGNC:7660]",{"v":32.2670992034376,"d":"32.27"},{"v":81.0461657156946,"d":"81.05"},{"v":0.398132335052454,"d":"0.40"},{"v":-1.32868004755907,"d":"-1.33"},{"v":0.0500383637245547,"d":"0.05"},{"v":0.668770228602761,"d":"0.67"},"down","no"]
["ENSG00000178075","GRAMD1C","ENST00000358160;ENST00000498183;ENST00000466898;ENST00000491038;ENST00000472384;ENST00000467895;ENST00000440446;ENST00000472026;ENST00000479212","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005515(protein binding);GO:0005515(protein binding)","NA","NA","NA","GRAM domain containing 1C [Source:HGNC Symbol;Acc:HGNC:25252]",{"v":0.13451752098797,"d":"0.13"},{"v":0.352852757870489,"d":"0.35"},{"v":0.381228481250367,"d":"0.38"},{"v":-1.39127218911345,"d":"-1.39"},{"v":0.0502866475457971,"d":"0.05"},{"v":0.6696981544396,"d":"0.67"},"down","no"]
["MSTRG.14195","NEIL2","ENST00000284503;ENST00000524741;ENST00000455213;ENST00000436750;ENST00000528113;ENST00000528323;ENST00000403422","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0005730(nucleolus);GO:0016787(hydrolase activity);GO:0016829(lyase activity);GO:0003677(DNA binding);GO:0003684(damaged DNA binding);GO:0006281(DNA repair);GO:0005515(protein binding);GO:0003824(catalytic activity);GO:0008152(metabolic process);GO:0016798(hydrolase activity, acting on glycosyl bonds);GO:0006974(cellular response to DNA damage stimulus);GO:0003906(DNA-(apurinic or apyrimidinic site) lyase activity);GO:0016799(hydrolase activity, hydrolyzing N-glycosyl compounds);GO:0006284(base-excision repair);GO:0006289(nucleotide-excision repair);GO:0005654(nucleoplasm);GO:0045008(depyrimidination);GO:0019104(DNA N-glycosylase activity);GO:0008017(microtubule binding);GO:0005737(cytoplasm);GO:0005876(spindle microtubule);GO:0015630(microtubule cytoskeleton);GO:0015630(microtubule cytoskeleton)","03410(Base excision repair);03410(Base excision repair)","K10568","EC:3.2.2.-;EC:4.2.99.18","nei like DNA glycosylase 2 [Source:HGNC Symbol;Acc:HGNC:18956]",{"v":1.49267445203445,"d":"1.49"},{"v":0.597638005940006,"d":"0.60"},{"v":2.49762303802394,"d":"2.50"},{"v":1.32055574987946,"d":"1.32"},{"v":0.0503229667451357,"d":"0.05"},{"v":0.6696981544396,"d":"0.67"},"up","no"]
["ENSG00000257743","MGAM2","ENST00000477922;ENST00000550469","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0030246(carbohydrate binding);GO:0003824(catalytic activity);GO:0005975(carbohydrate metabolic process);GO:0004553(hydrolase activity, hydrolyzing O-glycosyl compounds);GO:0004339(glucan 1,4-alpha-glucosidase activity);GO:0004339(glucan 1,4-alpha-glucosidase activity)","00052(Galactose metabolism);00500(Starch and sucrose metabolism);04973(Carbohydrate digestion and absorption);04973(Carbohydrate digestion and absorption)","K12047","EC:3.2.1.20;EC:3.2.1.3","maltase-glucoamylase 2 (putative) [Source:HGNC Symbol;Acc:HGNC:28101]",{"v":0.237509857632933,"d":"0.24"},{"v":0.612538153393776,"d":"0.61"},{"v":0.387747042885421,"d":"0.39"},{"v":-1.36681231615548,"d":"-1.37"},{"v":0.0504145751883763,"d":"0.05"},{"v":0.6696981544396,"d":"0.67"},"down","no"]
["MSTRG.11771","TET2","ENST00000380013;ENST00000305737;ENST00000413648;ENST00000514870;ENST00000505801;ENST00000265149","GO:0046872(metal ion binding);GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0016569(covalent chromatin modification);GO:0003677(DNA binding);GO:0008270(zinc ion binding);GO:0005515(protein binding);GO:0007049(cell cycle);GO:0051213(dioxygenase activity);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0006493(protein O-linked glycosylation);GO:0080182(histone H3-K4 trimethylation);GO:0070579(methylcytosine dioxygenase activity);GO:0080111(DNA demethylation);GO:0008198(ferrous iron binding);GO:0030099(myeloid cell differentiation);GO:0006211(5-methylcytosine catabolic process);GO:0014070(response to organic cyclic compound);GO:0014070(response to organic cyclic compound)","NA","NA","NA","tet methylcytosine dioxygenase 2 [Source:HGNC Symbol;Acc:HGNC:25941]",{"v":3.01217009621221,"d":"3.01"},{"v":7.55466233398082,"d":"7.55"},{"v":0.398716708047094,"d":"0.40"},{"v":-1.32656403278856,"d":"-1.33"},{"v":0.0504351268341259,"d":"0.05"},{"v":0.6696981544396,"d":"0.67"},"down","no"]
["ENSG00000274602","PI4KAP1","ENST00000610959;ENST00000611748;ENST00000618794;ENST00000616531;ENST00000612500;ENST00000617243;ENST00000619742","NA","NA","NA","NA","phosphatidylinositol 4-kinase alpha pseudogene 1 [Source:HGNC Symbol;Acc:HGNC:33576]",{"v":2.07775159164589,"d":"2.08"},{"v":0.847985479010806,"d":"0.85"},{"v":2.45022072084257,"d":"2.45"},{"v":1.29291171597153,"d":"1.29"},{"v":0.0504546244858854,"d":"0.05"},{"v":0.6696981544396,"d":"0.67"},"up","no"]
["ENSG00000256294","ZNF225","ENST00000262894;ENST00000588926;ENST00000592360","GO:0003676(nucleic acid binding);GO:0006355(regulation of transcription, DNA-templated);GO:0005622(intracellular);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding)","NA","NA","NA","zinc finger protein 225 [Source:HGNC Symbol;Acc:HGNC:13018]",{"v":0.217679621920841,"d":"0.22"},{"v":0.567657319955715,"d":"0.57"},{"v":0.383470122322783,"d":"0.38"},{"v":-1.38281391886953,"d":"-1.38"},{"v":0.0505417084351189,"d":"0.05"},{"v":0.6696981544396,"d":"0.67"},"down","no"]
["MSTRG.11458","CEP19","ENST00000409690","GO:0005737(cytoplasm);GO:0005813(centrosome);GO:0005856(cytoskeleton);GO:0042995(cell projection);GO:0005515(protein binding);GO:0000922(spindle pole);GO:0005814(centriole);GO:0036064(ciliary basal body)","NA","NA","NA","centrosomal protein 19 [Source:HGNC Symbol;Acc:HGNC:28209]",{"v":6.094056,"d":"6.09"},{"v":2.500605,"d":"2.50"},{"v":2.43703263810158,"d":"2.44"},{"v":1.28512557256802,"d":"1.29"},{"v":0.0505525972763263,"d":"0.05"},{"v":0.6696981544396,"d":"0.67"},"up","no"]
["MSTRG.10670","CAND2","ENST00000456430;ENST00000454887;ENST00000295989","GO:0005634(nucleus);GO:0006351(transcription, DNA-templated);GO:0045893(positive regulation of transcription, DNA-templated);GO:0005515(protein binding);GO:0005622(intracellular);GO:0016567(protein ubiquitination);GO:0010265(SCF complex assembly);GO:0017025(TBP-class protein binding);GO:0017025(TBP-class protein binding)","NA","NA","NA","cullin associated and neddylation dissociated 2 (putative) [Source:HGNC Symbol;Acc:HGNC:30689]",{"v":0.321990007667032,"d":"0.32"},{"v":0.125977885542169,"d":"0.13"},{"v":2.55592484570835,"d":"2.56"},{"v":1.35384541597274,"d":"1.35"},{"v":0.050552700746188,"d":"0.05"},{"v":0.6696981544396,"d":"0.67"},"up","no"]
["ENSG00000213533","TMEM110","ENST00000355083;ENST00000485356;ENST00000477591;ENST00000467979","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005515(protein binding);GO:0003674(molecular_function);GO:0008150(biological_process);GO:0005575(cellular_component);GO:0005246(calcium channel regulator activity);GO:0032541(cortical endoplasmic reticulum);GO:0035584(calcium-mediated signaling using intracellular calcium source);GO:0032237(activation of store-operated calcium channel activity);GO:0051533(positive regulation of NFAT protein import into nucleus);GO:0051533(positive regulation of NFAT protein import into nucleus)","NA","NA","NA","transmembrane protein 110 [Source:HGNC Symbol;Acc:HGNC:30526]",{"v":0.736423937172775,"d":"0.74"},{"v":1.86935696317627,"d":"1.87"},{"v":0.39394505794201,"d":"0.39"},{"v":-1.34393365850955,"d":"-1.34"},{"v":0.0506853804297322,"d":"0.05"},{"v":0.670449578576438,"d":"0.67"},"down","no"]
["ENSG00000180061","TMEM150B","ENST00000326652;ENST00000592731;ENST00000586609;ENST00000591570;ENST00000592603;ENST00000592891","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005886(plasma membrane);GO:0005887(integral component of plasma membrane);GO:0005764(lysosome);GO:0005764(lysosome)","NA","NA","NA","transmembrane protein 150B [Source:HGNC Symbol;Acc:HGNC:34415]",{"v":0.786982779334501,"d":"0.79"},{"v":2.04600695446585,"d":"2.05"},{"v":0.38464325725616,"d":"0.38"},{"v":-1.37840707656825,"d":"-1.38"},{"v":0.0507653951883731,"d":"0.05"},{"v":0.670449578576438,"d":"0.67"},"down","no"]
["ENSG00000076864","RAP1GAP","ENST00000464457;ENST00000447293;ENST00000611549;ENST00000542643;ENST00000290101","GO:0030695(GTPase regulator activity);GO:0050790(regulation of catalytic activity);GO:0043547(positive regulation of GTPase activity);GO:0005096(GTPase activator activity);GO:0051056(regulation of small GTPase mediated signal transduction);GO:0045665(negative regulation of neuron differentiation);GO:1904425(negative regulation of GTP binding);GO:1904442(negative regulation of thyroid gland epithelial cell proliferation);GO:1990792(cellular response to glial cell derived neurotrophic factor);GO:0005769(early endosome);GO:0005829(cytosol);GO:0016020(membrane);GO:0030424(axon);GO:0030425(dendrite);GO:0043025(neuronal cell body);GO:0005794(Golgi apparatus);GO:0042803(protein homodimerization activity);GO:0005515(protein binding);GO:0007165(signal transduction);GO:0000139(Golgi membrane);GO:0003924(GTPase activity);GO:0007411(axon guidance);GO:0043087(regulation of GTPase activity);GO:0017016(Ras GTPase binding);GO:1903697(negative regulation of microvillus assembly);GO:1903697(negative regulation of microvillus assembly)","04015(Rap1 signaling pathway);04015(Rap1 signaling pathway)","K17700","NA","RAP1 GTPase activating protein [Source:HGNC Symbol;Acc:HGNC:9858]",{"v":0.475190564378801,"d":"0.48"},{"v":0.190026384708949,"d":"0.19"},{"v":2.50065571213502,"d":"2.50"},{"v":1.32230644233031,"d":"1.32"},{"v":0.0507764503954253,"d":"0.05"},{"v":0.670449578576438,"d":"0.67"},"up","no"]
["ENSG00000127311","HELB","ENST00000247815;ENST00000440906;ENST00000545134;ENST00000545455;ENST00000542394","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0016787(hydrolase activity);GO:0004003(ATP-dependent DNA helicase activity);GO:0004386(helicase activity);GO:0032508(DNA duplex unwinding);GO:0005694(chromosome);GO:0006281(DNA repair);GO:0006974(cellular response to DNA damage stimulus);GO:0006260(DNA replication);GO:0006261(DNA-dependent DNA replication);GO:0006269(DNA replication, synthesis of RNA primer);GO:0003723(RNA binding);GO:0004004(ATP-dependent RNA helicase activity);GO:0035861(site of double-strand break);GO:0005662(DNA replication factor A complex);GO:2000042(negative regulation of double-strand break repair via homologous recombination);GO:0005658(alpha DNA polymerase:primase complex);GO:0043141(ATP-dependent 5'-3' DNA helicase activity);GO:0006396(RNA processing);GO:0017116(single-stranded DNA-dependent ATP-dependent DNA helicase activity);GO:1903775(regulation of DNA double-strand break processing);GO:1903775(regulation of DNA double-strand break processing)","NA","NA","NA","DNA helicase B [Source:HGNC Symbol;Acc:HGNC:17196]",{"v":0.467571292693534,"d":"0.47"},{"v":1.17632981900551,"d":"1.18"},{"v":0.397483159177948,"d":"0.40"},{"v":-1.33103435822659,"d":"-1.33"},{"v":0.0509137459122784,"d":"0.05"},{"v":0.671076214989582,"d":"0.67"},"down","no"]
["MSTRG.8707","EML6","ENST00000356458;ENST00000490828;ENST00000491655;ENST00000488611","GO:0005737(cytoplasm);GO:0005856(cytoskeleton);GO:0005874(microtubule);GO:0008017(microtubule binding);GO:0015630(microtubule cytoskeleton);GO:0015630(microtubule cytoskeleton)","NA","NA","NA","echinoderm microtubule associated protein like 6 [Source:HGNC Symbol;Acc:HGNC:35412]",{"v":0.159609505060308,"d":"0.16"},{"v":0.0637570608623319,"d":"0.06"},{"v":2.50340123747151,"d":"2.50"},{"v":1.32388954029459,"d":"1.32"},{"v":0.0509353645989435,"d":"0.05"},{"v":0.671076214989582,"d":"0.67"},"up","no"]
["ENSG00000116922","C1orf109","ENST00000477060;ENST00000464178;ENST00000461359;ENST00000609516;ENST00000486637;ENST00000488137;ENST00000494120;ENST00000498448;ENST00000491797;ENST00000464085;ENST00000358011","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005515(protein binding);GO:0005515(protein binding)","NA","NA","NA","chromosome 1 open reading frame 109 [Source:HGNC Symbol;Acc:HGNC:26039]",{"v":0.766621441136671,"d":"0.77"},{"v":0.301673969778981,"d":"0.30"},{"v":2.54122502414885,"d":"2.54"},{"v":1.34552413094019,"d":"1.35"},{"v":0.0512322551723942,"d":"0.05"},{"v":0.673536060310878,"d":"0.67"},"up","no"]
["ENSG00000087502","ERGIC2","ENST00000360150;ENST00000552155;ENST00000548909;ENST00000549182;ENST00000546839;ENST00000552132;ENST00000546509;ENST00000611644;ENST00000550353;ENST00000548098;ENST00000548441","GO:0006810(transport);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0043231(intracellular membrane-bounded organelle);GO:0005730(nucleolus);GO:0005794(Golgi apparatus);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0016192(vesicle-mediated transport);GO:0005515(protein binding);GO:0033116(endoplasmic reticulum-Golgi intermediate compartment membrane);GO:0006890(retrograde vesicle-mediated transport, Golgi to ER);GO:0006890(retrograde vesicle-mediated transport, Golgi to ER)","NA","NA","NA","ERGIC and golgi 2 [Source:HGNC Symbol;Acc:HGNC:30208]",{"v":1.7799053038105,"d":"1.78"},{"v":4.46830988911775,"d":"4.47"},{"v":0.398339718591437,"d":"0.40"},{"v":-1.32792875639036,"d":"-1.33"},{"v":0.0512464164386676,"d":"0.05"},{"v":0.673536060310878,"d":"0.67"},"down","no"]
["MSTRG.9642","HCK","MSTRG.9642.2;ENST00000518730;ENST00000375862;ENST00000639405;ENST00000262651;ENST00000534862;ENST00000375852;ENST00000520553;ENST00000470092;ENST00000538448;ENST00000629881;MSTRG.9642.1","GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0005654(nucleoplasm);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0004713(protein tyrosine kinase activity);GO:0018108(peptidyl-tyrosine phosphorylation);GO:0005886(plasma membrane);GO:0004715(non-membrane spanning protein tyrosine kinase activity);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0007155(cell adhesion);GO:0005794(Golgi apparatus);GO:0005829(cytosol);GO:0005856(cytoskeleton);GO:0042995(cell projection);GO:0005515(protein binding);GO:0005901(caveola);GO:0030054(cell junction);GO:0031410(cytoplasmic vesicle);GO:0007229(integrin-mediated signaling pathway);GO:0002376(immune system process);GO:0045087(innate immune response);GO:0005925(focal adhesion);GO:0005764(lysosome);GO:0006954(inflammatory response);GO:0038096(Fc-gamma receptor signaling pathway involved in phagocytosis);GO:0006887(exocytosis);GO:0031234(extrinsic component of cytoplasmic side of plasma membrane);GO:0016032(viral process);GO:0030154(cell differentiation);GO:0008360(regulation of cell shape);GO:0008284(positive regulation of cell proliferation);GO:0051090(regulation of sequence-specific DNA binding transcription factor activity);GO:0043066(negative regulation of apoptotic process);GO:0006909(phagocytosis);GO:0046777(protein autophosphorylation);GO:0001784(phosphotyrosine residue binding);GO:0005884(actin filament);GO:0030838(positive regulation of actin filament polymerization);GO:0030133(transport vesicle);GO:0005102(receptor binding);GO:0019221(cytokine-mediated signaling pathway);GO:0007498(mesoderm development);GO:0050764(regulation of phagocytosis);GO:0050690(regulation of defense response to virus by virus);GO:0038083(peptidyl-tyrosine autophosphorylation);GO:0050727(regulation of inflammatory response);GO:0007169(transmembrane receptor protein tyrosine kinase signaling pathway);GO:0031663(lipopolysaccharide-mediated signaling pathway);GO:0071801(regulation of podosome assembly);GO:2000251(positive regulation of actin cytoskeleton reorganization);GO:0002522(leukocyte migration involved in immune response);GO:0002758(innate immune response-activating signal transduction);GO:0043299(leukocyte degranulation);GO:0045728(respiratory burst after phagocytosis);GO:0060333(interferon-gamma-mediated signaling pathway);GO:0060333(interferon-gamma-mediated signaling pathway)","04666(Fc gamma R-mediated phagocytosis);04062(Chemokine signaling pathway);05167(Kaposi's sarcoma-associated herpesvirus infection);05167(Kaposi's sarcoma-associated herpesvirus infection)","K08893","EC:2.7.10.2","HCK proto-oncogene, Src family tyrosine kinase [Source:HGNC Symbol;Acc:HGNC:4840]",{"v":26.8648181902258,"d":"26.86"},{"v":67.1330985487164,"d":"67.13"},{"v":0.400172474844593,"d":"0.40"},{"v":-1.321306157456,"d":"-1.32"},{"v":0.0512898660774851,"d":"0.05"},{"v":0.673536060310878,"d":"0.67"},"down","no"]
["MSTRG.9290","SSFA2","ENST00000409001;ENST00000320370;ENST00000409136;ENST00000431877;ENST00000467172;ENST00000495248;ENST00000491866;ENST00000454579;ENST00000440623;ENST00000491720;ENST00000480753","GO:0005737(cytoplasm);GO:0005634(nucleus);GO:0005829(cytosol);GO:0003779(actin binding);GO:0005886(plasma membrane);GO:0005102(receptor binding);GO:0051015(actin filament binding);GO:0051015(actin filament binding)","NA","NA","NA","sperm specific antigen 2 [Source:HGNC Symbol;Acc:HGNC:11319]",{"v":2.58410485211856,"d":"2.58"},{"v":6.46378237925277,"d":"6.46"},{"v":0.399782155478027,"d":"0.40"},{"v":-1.32271401694665,"d":"-1.32"},{"v":0.0513801475939704,"d":"0.05"},{"v":0.673765808862929,"d":"0.67"},"down","no"]
["ENSG00000265992","ESRG","ENST00000583516","NA","NA","NA","NA","embryonic stem cell related (non-protein coding) [Source:HGNC Symbol;Acc:HGNC:39079]",{"v":0.65895,"d":"0.66"},{"v":0.259116,"d":"0.26"},{"v":2.54306951326819,"d":"2.54"},{"v":1.34657089776402,"d":"1.35"},{"v":0.0514192641043873,"d":"0.05"},{"v":0.673765808862929,"d":"0.67"},"up","no"]
["ENSG00000130881","LRP3","ENST00000253193;ENST00000590278;ENST00000592484","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005905(clathrin-coated pit);GO:0006897(endocytosis);GO:0006898(receptor-mediated endocytosis);GO:0006898(receptor-mediated endocytosis)","NA","NA","NA","LDL receptor related protein 3 [Source:HGNC Symbol;Acc:HGNC:6695]",{"v":0.411996974288518,"d":"0.41"},{"v":1.05362314347399,"d":"1.05"},{"v":0.3910287818186,"d":"0.39"},{"v":-1.35465329334258,"d":"-1.35"},{"v":0.0515319041116491,"d":"0.05"},{"v":0.674507814470086,"d":"0.67"},"down","no"]
["ENSG00000163617","CCDC191","ENST00000295878;ENST00000481358;ENST00000460813;ENST00000527855","NA","NA","NA","NA","coiled-coil domain containing 191 [Source:HGNC Symbol;Acc:HGNC:29272]",{"v":1.01670407033754,"d":"1.02"},{"v":0.413892815953234,"d":"0.41"},{"v":2.45644290296746,"d":"2.46"},{"v":1.29657070578422,"d":"1.30"},{"v":0.0516695837369093,"d":"0.05"},{"v":0.675362751220567,"d":"0.68"},"up","no"]
["MSTRG.12727","HIST1H2BC","ENST00000314332;ENST00000396984","GO:0005634(nucleus);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0003677(DNA binding);GO:0046982(protein heterodimerization activity);GO:0006334(nucleosome assembly);GO:0000786(nucleosome);GO:0005694(chromosome);GO:0005515(protein binding);GO:0005615(extracellular space);GO:0042742(defense response to bacterium);GO:0016567(protein ubiquitination);GO:0070062(extracellular exosome);GO:0002227(innate immune response in mucosa);GO:0019731(antibacterial humoral response);GO:0050830(defense response to Gram-positive bacterium);GO:0061844(antimicrobial humoral immune response mediated by antimicrobial peptide);GO:0061844(antimicrobial humoral immune response mediated by antimicrobial peptide)","05203(Viral carcinogenesis);05322(Systemic lupus erythematosus);05034(Alcoholism);05034(Alcoholism)","K11252","NA","histone cluster 1 H2B family member c [Source:HGNC Symbol;Acc:HGNC:4757]",{"v":2.44177559952038,"d":"2.44"},{"v":6.2085066235012,"d":"6.21"},{"v":0.393295158980337,"d":"0.39"},{"v":-1.34631566644545,"d":"-1.35"},{"v":0.0517093885256072,"d":"0.05"},{"v":0.675362751220567,"d":"0.68"},"down","no"]
["MSTRG.2976","ST3GAL4","ENST00000444328;ENST00000526727;ENST00000227495;ENST00000524834;ENST00000534733;ENST00000534457;ENST00000526311;ENST00000532243;ENST00000533826;ENST00000528858;ENST00000356132;ENST00000524860;ENST00000534083;ENST00000534452;ENST00000528605;ENST00000530591","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016740(transferase activity);GO:0008373(sialyltransferase activity);GO:0016757(transferase activity, transferring glycosyl groups);GO:0006486(protein glycosylation);GO:0097503(sialylation);GO:0005794(Golgi apparatus);GO:0005576(extracellular region);GO:0032580(Golgi cisterna membrane);GO:0070062(extracellular exosome);GO:0000139(Golgi membrane);GO:0050890(cognition);GO:0016266(O-glycan processing);GO:0018146(keratan sulfate biosynthetic process);GO:0009311(oligosaccharide metabolic process);GO:0003836(beta-galactoside (CMP) alpha-2,3-sialyltransferase activity);GO:0018279(protein N-linked glycosylation via asparagine);GO:0047288(monosialoganglioside sialyltransferase activity);GO:0047288(monosialoganglioside sialyltransferase activity)","00601(Glycosphingolipid biosynthesis - lacto and neolacto series);00601(Glycosphingolipid biosynthesis - lacto and neolacto series)","K03494","EC:2.4.99.4","ST3 beta-galactoside alpha-2,3-sialyltransferase 4 [Source:HGNC Symbol;Acc:HGNC:10864]",{"v":1.41661934199328,"d":"1.42"},{"v":3.57792117110862,"d":"3.58"},{"v":0.395933636948838,"d":"0.40"},{"v":-1.33666945667355,"d":"-1.34"},{"v":0.0519007943926396,"d":"0.05"},{"v":0.676428282004589,"d":"0.68"},"down","no"]
["ENSG00000025039","RRAGD","ENST00000369415;ENST00000492783;ENST00000359203","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005525(GTP binding);GO:0000166(nucleotide binding);GO:0005654(nucleoplasm);GO:0005813(centrosome);GO:0005515(protein binding);GO:0005764(lysosome);GO:0034448(EGO complex);GO:0071230(cellular response to amino acid stimulus);GO:0005829(cytosol);GO:0046982(protein heterodimerization activity);GO:0032008(positive regulation of TOR signaling);GO:0003924(GTPase activity);GO:0007050(cell cycle arrest);GO:0016241(regulation of macroautophagy);GO:0010506(regulation of autophagy);GO:0019003(GDP binding);GO:0034613(cellular protein localization);GO:0071233(cellular response to leucine);GO:1990253(cellular response to leucine starvation);GO:0051020(GTPase binding);GO:1904263(positive regulation of TORC1 signaling);GO:1990131(Gtr1-Gtr2 GTPase complex);GO:1990131(Gtr1-Gtr2 GTPase complex)","04150(mTOR signaling pathway);04140(Autophagy - animal);04140(Autophagy - animal)","K16186","NA","Ras related GTP binding D [Source:HGNC Symbol;Acc:HGNC:19903]",{"v":1.06066257886435,"d":"1.06"},{"v":2.66335237342271,"d":"2.66"},{"v":0.398243427887568,"d":"0.40"},{"v":-1.32827754137846,"d":"-1.33"},{"v":0.0519238997283539,"d":"0.05"},{"v":0.676428282004589,"d":"0.68"},"down","no"]
["ENSG00000111711","GOLT1B","ENST00000539025;ENST00000545113;ENST00000535593;ENST00000542194;ENST00000545093;ENST00000229314","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016192(vesicle-mediated transport);GO:0006810(transport);GO:0015031(protein transport);GO:0005794(Golgi apparatus);GO:0004871(signal transducer activity);GO:0000139(Golgi membrane);GO:0007165(signal transduction);GO:0005783(endoplasmic reticulum);GO:0043123(positive regulation of I-kappaB kinase/NF-kappaB signaling);GO:0043123(positive regulation of I-kappaB kinase/NF-kappaB signaling)","NA","NA","NA","golgi transport 1B [Source:HGNC Symbol;Acc:HGNC:20175]",{"v":0.79958051121668,"d":"0.80"},{"v":2.02837031802586,"d":"2.03"},{"v":0.394198487382167,"d":"0.39"},{"v":-1.34300585440255,"d":"-1.34"},{"v":0.0519594885280057,"d":"0.05"},{"v":0.676428282004589,"d":"0.68"},"down","no"]
["ENSG00000182109","AL365277.1","ENST00000458207;ENST00000417869;ENST00000441741;ENST00000431553;ENST00000331856","NA","NA","NA","NA",null,{"v":0.574720030075188,"d":"0.57"},{"v":0.221831604445897,"d":"0.22"},{"v":2.5907941815178,"d":"2.59"},{"v":1.37339440915066,"d":"1.37"},{"v":0.0521994825378026,"d":"0.05"},{"v":0.678060734252106,"d":"0.68"},"up","no"]
["ENSG00000225783","MIAT","ENST00000613780;ENST00000620145;ENST00000452429;ENST00000436238;ENST00000616469;ENST00000449717;ENST00000458302;ENST00000453023;ENST00000616213;ENST00000421867;ENST00000439738;ENST00000425476;ENST00000413665;ENST00000450203","NA","NA","NA","NA","myocardial infarction associated transcript (non-protein coding) [Source:HGNC Symbol;Acc:HGNC:33425]",{"v":1.35368323815732,"d":"1.35"},{"v":0.559142166623207,"d":"0.56"},{"v":2.42100009436336,"d":"2.42"},{"v":1.2756031355688,"d":"1.28"},{"v":0.0522461741784941,"d":"0.05"},{"v":0.678060734252106,"d":"0.68"},"up","no"]
["MSTRG.14920","ORM1","ENST00000259396;ENST00000477456","GO:0006810(transport);GO:0005615(extracellular space);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0070062(extracellular exosome);GO:0072562(blood microparticle);GO:0043312(neutrophil degranulation);GO:0006953(acute-phase response);GO:0006954(inflammatory response);GO:0050718(positive regulation of interleukin-1 beta secretion);GO:1904469(positive regulation of tumor necrosis factor secretion);GO:0002576(platelet degranulation);GO:0031093(platelet alpha granule lumen);GO:0035580(specific granule lumen);GO:1904724(tertiary granule lumen);GO:0050716(positive regulation of interleukin-1 secretion);GO:0002682(regulation of immune system process);GO:0032715(negative regulation of interleukin-6 production);GO:0032720(negative regulation of tumor necrosis factor production);GO:0032720(negative regulation of tumor necrosis factor production)","NA","NA","NA","orosomucoid 1 [Source:HGNC Symbol;Acc:HGNC:8498]",{"v":1.44563303884573,"d":"1.45"},{"v":3.71517643285239,"d":"3.72"},{"v":0.389115581715677,"d":"0.39"},{"v":-1.36172934224598,"d":"-1.36"},{"v":0.0523071440467903,"d":"0.05"},{"v":0.678060734252106,"d":"0.68"},"down","no"]
["ENSG00000211445","GPX3","ENST00000622181;ENST00000520597;ENST00000520059;ENST00000388825;ENST00000521650;ENST00000521722;ENST00000519214","GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0005615(extracellular space);GO:0098869(cellular oxidant detoxification);GO:0004601(peroxidase activity);GO:0004602(glutathione peroxidase activity);GO:0006979(response to oxidative stress);GO:0070062(extracellular exosome);GO:0042744(hydrogen peroxide catabolic process);GO:0008134(transcription factor binding);GO:0051289(protein homotetramerization);GO:0034599(cellular response to oxidative stress);GO:0008430(selenium binding);GO:0006982(response to lipid hydroperoxide);GO:0006982(response to lipid hydroperoxide)","00590(Arachidonic acid metabolism);00480(Glutathione metabolism);04918(Thyroid hormone synthesis);04918(Thyroid hormone synthesis)","K00432","EC:1.11.1.9","glutathione peroxidase 3 [Source:HGNC Symbol;Acc:HGNC:4555]",{"v":0.56981984445147,"d":"0.57"},{"v":1.4543735384129,"d":"1.45"},{"v":0.391797450518312,"d":"0.39"},{"v":-1.35182008507297,"d":"-1.35"},{"v":0.0523273674124462,"d":"0.05"},{"v":0.678060734252106,"d":"0.68"},"down","no"]
["MSTRG.5824","AC012645.1","ENST00000515455","NA","NA","NA","NA",null,{"v":0.523999,"d":"0.52"},{"v":1.378006,"d":"1.38"},{"v":0.380258866797387,"d":"0.38"},{"v":-1.39494620608164,"d":"-1.39"},{"v":0.0523664244190715,"d":"0.05"},{"v":0.678060734252106,"d":"0.68"},"down","no"]
["MSTRG.7355","SLC16A3","MSTRG.7355.4;MSTRG.7355.5;ENST00000581287;ENST00000582743;ENST00000583444;ENST00000581642;ENST00000578810;ENST00000578684;ENST00000617373;ENST00000583237;ENST00000583025;ENST00000579572;ENST00000582946;ENST00000392341;ENST00000584781;ENST00000580098;ENST00000578522;ENST00000580189;ENST00000619321;ENST00000577650;ENST00000392339;ENST00000584689;ENST00000578574","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0055085(transmembrane transport);GO:0005887(integral component of plasma membrane);GO:0008028(monocarboxylic acid transmembrane transporter activity);GO:0015129(lactate transmembrane transporter activity);GO:0015718(monocarboxylic acid transport);GO:0035873(lactate transmembrane transport);GO:0003723(RNA binding);GO:0006810(transport);GO:0031965(nuclear membrane);GO:0005886(plasma membrane);GO:0015293(symporter activity);GO:0005515(protein binding);GO:0050900(leukocyte migration);GO:0006090(pyruvate metabolic process);GO:0035879(plasma membrane lactate transport);GO:0035879(plasma membrane lactate transport)","05230(Central carbon metabolism in cancer);05230(Central carbon metabolism in cancer)","K08180","NA","solute carrier family 16 member 3 [Source:HGNC Symbol;Acc:HGNC:10924]",{"v":4.65950421478599,"d":"4.66"},{"v":11.6166364040022,"d":"11.62"},{"v":0.401106142323666,"d":"0.40"},{"v":-1.3179440359101,"d":"-1.32"},{"v":0.0524522257341279,"d":"0.05"},{"v":0.678442215134659,"d":"0.68"},"down","no"]
["ENSG00000130731","METTL26","ENST00000301686;ENST00000397664;ENST00000565799;ENST00000568077;ENST00000568830;ENST00000456420;ENST00000397665;ENST00000568773;ENST00000338401;ENST00000397666;ENST00000448973;ENST00000564039","NA","NA","NA","NA","methyltransferase like 26 [Source:HGNC Symbol;Acc:HGNC:14141]",{"v":4.38008132568306,"d":"4.38"},{"v":1.77871554098361,"d":"1.78"},{"v":2.46249679881974,"d":"2.46"},{"v":1.3001218491051,"d":"1.30"},{"v":0.052554517921824,"d":"0.05"},{"v":0.679035949371893,"d":"0.68"},"up","no"]
["ENSG00000006530","AGK","ENST00000355413;ENST00000494053;ENST00000629555;ENST00000496784;ENST00000495028;ENST00000492693;ENST00000473247","GO:0016020(membrane);GO:0043231(intracellular membrane-bounded organelle);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0005739(mitochondrion);GO:0008152(metabolic process);GO:0003951(NAD+ kinase activity);GO:0004143(diacylglycerol kinase activity);GO:0031966(mitochondrial membrane);GO:0005829(cytosol);GO:0001727(lipid kinase activity);GO:0001729(ceramide kinase activity);GO:0046513(ceramide biosynthetic process);GO:0046834(lipid phosphorylation);GO:0005741(mitochondrial outer membrane);GO:0046474(glycerophospholipid biosynthetic process);GO:0046486(glycerolipid metabolic process);GO:0047620(acylglycerol kinase activity);GO:0047620(acylglycerol kinase activity)","00561(Glycerolipid metabolism);00561(Glycerolipid metabolism)","K09881","EC:2.7.1.94","acylglycerol kinase [Source:HGNC Symbol;Acc:HGNC:21869]",{"v":1.98169225110738,"d":"1.98"},{"v":0.817270091339545,"d":"0.82"},{"v":2.42477030801322,"d":"2.42"},{"v":1.27784809114104,"d":"1.28"},{"v":0.0527300388126875,"d":"0.05"},{"v":0.679062312291212,"d":"0.68"},"up","no"]
["MSTRG.9778","SNX21","ENST00000372542;ENST00000478230;ENST00000472219;ENST00000466252;ENST00000344780;ENST00000462307;ENST00000491381;ENST00000372547;ENST00000486336;ENST00000614929;ENST00000372541","GO:0006810(transport);GO:0016020(membrane);GO:0015031(protein transport);GO:0030659(cytoplasmic vesicle membrane);GO:0031410(cytoplasmic vesicle);GO:0035091(phosphatidylinositol binding);GO:0008289(lipid binding);GO:0005768(endosome);GO:0032266(phosphatidylinositol-3-phosphate binding);GO:0031901(early endosome membrane);GO:0005546(phosphatidylinositol-4,5-bisphosphate binding);GO:0005546(phosphatidylinositol-4,5-bisphosphate binding)","NA","NA","NA","sorting nexin family member 21 [Source:HGNC Symbol;Acc:HGNC:16154]",{"v":0.164579822429907,"d":"0.16"},{"v":0.458791233152976,"d":"0.46"},{"v":0.358724863373818,"d":"0.36"},{"v":-1.47905035231569,"d":"-1.48"},{"v":0.0527415526280477,"d":"0.05"},{"v":0.679062312291212,"d":"0.68"},"down","no"]
["MSTRG.11545","FBXL5","MSTRG.11545.1;ENST00000341285;MSTRG.11545.4;ENST00000412094;ENST00000507700;ENST00000503196;ENST00000509314;MSTRG.11545.5;ENST00000512066;ENST00000510802;ENST00000515679;ENST00000507899;MSTRG.11545.2;ENST00000514541;ENST00000511441;ENST00000504837;ENST00000513163;MSTRG.11545.9","GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0016567(protein ubiquitination);GO:0005515(protein binding);GO:0048471(perinuclear region of cytoplasm);GO:0005506(iron ion binding);GO:0005829(cytosol);GO:0000209(protein polyubiquitination);GO:0043687(post-translational protein modification);GO:0004842(ubiquitin-protein transferase activity);GO:0000151(ubiquitin ligase complex);GO:0006879(cellular iron ion homeostasis);GO:0055072(iron ion homeostasis);GO:0019005(SCF ubiquitin ligase complex);GO:0031146(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process);GO:1903364(positive regulation of cellular protein catabolic process);GO:1903364(positive regulation of cellular protein catabolic process)","NA","NA","NA","F-box and leucine rich repeat protein 5 [Source:HGNC Symbol;Acc:HGNC:13602]",{"v":14.2884971645917,"d":"14.29"},{"v":35.4779347940315,"d":"35.48"},{"v":0.402743204967936,"d":"0.40"},{"v":-1.31206784671718,"d":"-1.31"},{"v":0.0529061821626771,"d":"0.05"},{"v":0.679062312291212,"d":"0.68"},"down","no"]
["ENSG00000240583","AQP1","ENST00000311813;ENST00000409611","GO:0006810(transport);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005215(transporter activity);GO:0098655(cation transmembrane transport);GO:0005886(plasma membrane);GO:0005267(potassium channel activity);GO:0006813(potassium ion transport);GO:0005515(protein binding);GO:0071805(potassium ion transmembrane transport);GO:0005372(water transmembrane transporter activity);GO:0015079(potassium ion transmembrane transporter activity);GO:0015168(glycerol transmembrane transporter activity);GO:0015250(water channel activity);GO:0046875(ephrin receptor binding);GO:0003094(glomerular filtration);GO:0006833(water transport);GO:0006972(hyperosmotic response);GO:0009725(response to hormone);GO:0010592(positive regulation of lamellipodium assembly);GO:0010634(positive regulation of epithelial cell migration);GO:0015793(glycerol transport);GO:0019233(sensory perception of pain);GO:0021670(lateral ventricle development);GO:0030104(water homeostasis);GO:0030335(positive regulation of cell migration);GO:0032940(secretion by cell);GO:0033363(secretory granule organization);GO:0042060(wound healing);GO:0042538(hyperosmotic salinity response);GO:0043627(response to estrogen);GO:0044241(lipid digestion);GO:0048593(camera-type eye morphogenesis);GO:0051458(corticotropin secretion);GO:0070295(renal water absorption);GO:0072220(metanephric descending thin limb development);GO:0072230(metanephric proximal straight tubule development);GO:0072232(metanephric proximal convoluted tubule segment 2 development);GO:0072239(metanephric glomerulus vasculature development);GO:0085018(maintenance of symbiont-containing vacuole by host);GO:0005901(caveola);GO:0005903(brush border);GO:0009925(basal plasma membrane);GO:0016323(basolateral plasma membrane);GO:0016324(apical plasma membrane);GO:0020003(symbiont-containing vacuole);GO:0030424(axon);GO:0032809(neuronal cell body membrane);GO:0043005(neuron projection);GO:0043679(axon terminus);GO:0070062(extracellular exosome);GO:0072488(ammonium transmembrane transport);GO:0006182(cGMP biosynthetic process);GO:0042383(sarcolemma);GO:0005887(integral component of plasma membrane);GO:0043066(negative regulation of apoptotic process);GO:0031965(nuclear membrane);GO:0071260(cellular response to mechanical stimulus);GO:0031526(brush border membrane);GO:0043154(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process);GO:0071300(cellular response to retinoic acid);GO:0045766(positive regulation of angiogenesis);GO:0048146(positive regulation of fibroblast proliferation);GO:0071456(cellular response to hypoxia);GO:0003091(renal water homeostasis);GO:0071320(cellular response to cAMP);GO:0015701(bicarbonate transport);GO:0045177(apical part of cell);GO:0022857(transmembrane transporter activity);GO:0042493(response to drug);GO:0070301(cellular response to hydrogen peroxide);GO:0034644(cellular response to UV);GO:0020005(symbiont-containing vacuole membrane);GO:0042476(odontogenesis);GO:0030157(pancreatic juice secretion);GO:0035377(transepithelial water transport);GO:0050891(multicellular organismal water homeostasis);GO:0071280(cellular response to copper ion);GO:0071732(cellular response to nitric oxide);GO:0071472(cellular response to salt stress);GO:0033554(cellular response to stress);GO:0005223(intracellular cGMP activated cation channel activity);GO:0008519(ammonium transmembrane transporter activity);GO:0030184(nitric oxide transmembrane transporter activity);GO:0035379(carbon dioxide transmembrane transporter activity);GO:0003097(renal water transport);GO:0006884(cell volume homeostasis);GO:0015670(carbon dioxide transport);GO:0015696(ammonium transport);GO:0019725(cellular homeostasis);GO:0030185(nitric oxide transport);GO:0030950(establishment or maintenance of actin cytoskeleton polarity);GO:0033326(cerebrospinal fluid secretion);GO:0035378(carbon dioxide transmembrane transport);GO:0046878(positive regulation of saliva secretion);GO:0071241(cellular response to inorganic substance);GO:0071288(cellular response to mercury ion);GO:0071474(cellular hyperosmotic response);GO:0071549(cellular response to dexamethasone stimulus);GO:0071549(cellular response to dexamethasone stimulus)","04924(Renin secretion);04976(Bile secretion);04964(Proximal tubule bicarbonate reclamation);04964(Proximal tubule bicarbonate reclamation)","K09864","NA","aquaporin 1 (Colton blood group) [Source:HGNC Symbol;Acc:HGNC:633]",{"v":0.501580234061135,"d":"0.50"},{"v":1.28634579213974,"d":"1.29"},{"v":0.389926439007348,"d":"0.39"},{"v":-1.35872611473094,"d":"-1.36"},{"v":0.0529613548032086,"d":"0.05"},{"v":0.679062312291212,"d":"0.68"},"down","no"]
["MSTRG.4098","IRS2","ENST00000375856","GO:0008284(positive regulation of cell proliferation);GO:0046326(positive regulation of glucose import);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0043547(positive regulation of GTPase activity);GO:0005515(protein binding);GO:0004871(signal transducer activity);GO:0007165(signal transduction);GO:0005158(insulin receptor binding);GO:0036092(phosphatidylinositol-3-phosphate biosynthetic process);GO:0005886(plasma membrane);GO:0046854(phosphatidylinositol phosphorylation);GO:0000165(MAPK cascade);GO:0008286(insulin receptor signaling pathway);GO:0032024(positive regulation of insulin secretion);GO:0046934(phosphatidylinositol-4,5-bisphosphate 3-kinase activity);GO:0007411(axon guidance);GO:0014066(regulation of phosphatidylinositol 3-kinase signaling);GO:0038111(interleukin-7-mediated signaling pathway);GO:0048015(phosphatidylinositol-mediated signaling);GO:0005088(Ras guanyl-nucleotide exchange factor activity);GO:0016303(1-phosphatidylinositol-3-kinase activity);GO:0043548(phosphatidylinositol 3-kinase binding);GO:0032869(cellular response to insulin stimulus);GO:0045725(positive regulation of glycogen biosynthetic process);GO:0009749(response to glucose);GO:0030890(positive regulation of B cell proliferation);GO:0055088(lipid homeostasis);GO:0010748(negative regulation of plasma membrane long-chain fatty acid transport);GO:0006006(glucose metabolic process);GO:0010907(positive regulation of glucose metabolic process);GO:0032000(positive regulation of fatty acid beta-oxidation);GO:0019216(regulation of lipid metabolic process);GO:0019901(protein kinase binding);GO:0019903(protein phosphatase binding);GO:0019904(protein domain specific binding);GO:0071889(14-3-3 protein binding);GO:0002053(positive regulation of mesenchymal cell proliferation);GO:0002903(negative regulation of B cell apoptotic process);GO:0007420(brain development);GO:0008283(cell proliferation);GO:0030335(positive regulation of cell migration);GO:0030879(mammary gland development);GO:0033673(negative regulation of kinase activity);GO:0071333(cellular response to glucose stimulus);GO:1901653(cellular response to peptide);GO:0043234(protein complex)","04068(FoxO signaling pathway);04022(cGMP - PKG signaling pathway);04152(AMPK signaling pathway);04140(Autophagy - animal);04910(Insulin signaling pathway);04923(Regulation of lipolysis in adipocyte);04920(Adipocytokine signaling pathway);04211(Longevity regulating pathway - mammal);04213(Longevity regulating pathway - multiple species);05206(MicroRNAs in cancer);04930(Type II diabetes mellitus);04932(Non-alcoholic fatty liver disease (NAFLD));04931(Insulin resistance)","K07187","NA","insulin receptor substrate 2 [Source:HGNC Symbol;Acc:HGNC:6126]",{"v":1.570779,"d":"1.57"},{"v":3.909143,"d":"3.91"},{"v":0.401821831536989,"d":"0.40"},{"v":-1.31537214506574,"d":"-1.32"},{"v":0.0529651153917087,"d":"0.05"},{"v":0.679062312291212,"d":"0.68"},"down","no"]
["MSTRG.6660","AC134669.2;EVI2A;EVI2B","MSTRG.6660.2;ENST00000462804;ENST00000577894;ENST00000247270;ENST00000461237;ENST00000584948;MSTRG.6660.4;MSTRG.6660.3;MSTRG.6660.1;ENST00000330927;ENST00000578584;ENST00000578021","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0007165(signal transduction);GO:0004888(transmembrane signaling receptor activity);GO:0005887(integral component of plasma membrane);GO:0016021(integral component of membrane)","NA","NA","NA","ecotropic viral integration site 2A [Source:HGNC Symbol;Acc:HGNC:3499];ecotropic viral integration site 2B [Source:HGNC Symbol;Acc:HGNC:3500]",{"v":86.9198192806464,"d":"86.92"},{"v":215.580205178952,"d":"215.58"},{"v":0.40319016863582,"d":"0.40"},{"v":-1.31046763420745,"d":"-1.31"},{"v":0.0530446902290291,"d":"0.05"},{"v":0.679062312291212,"d":"0.68"},"down","no"]
["MSTRG.942","CDC42SE1","ENST00000357235;ENST00000483763;ENST00000492796;ENST00000540998;MSTRG.942.1;ENST00000491825;MSTRG.942.5;ENST00000470278","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005886(plasma membrane);GO:0005856(cytoskeleton);GO:0008360(regulation of cell shape);GO:0007165(signal transduction);GO:0005198(structural molecule activity);GO:0006909(phagocytosis);GO:0005095(GTPase inhibitor activity);GO:0034260(negative regulation of GTPase activity);GO:0034260(negative regulation of GTPase activity)","NA","NA","NA","CDC42 small effector 1 [Source:HGNC Symbol;Acc:HGNC:17719]",{"v":27.436183200492,"d":"27.44"},{"v":68.0789928936039,"d":"68.08"},{"v":0.403005127343323,"d":"0.40"},{"v":-1.3111299009338,"d":"-1.31"},{"v":0.0530458956761194,"d":"0.05"},{"v":0.679062312291212,"d":"0.68"},"down","no"]
["MSTRG.14206","ATP6V1B2","ENST00000276390;ENST00000523482;MSTRG.14206.1;ENST00000523478;MSTRG.14206.3;ENST00000521442;ENST00000520830","GO:0006810(transport);GO:0016020(membrane);GO:0043231(intracellular membrane-bounded organelle);GO:0005524(ATP binding);GO:0016787(hydrolase activity);GO:0005765(lysosomal membrane);GO:0005829(cytosol);GO:0015992(proton transport);GO:0006811(ion transport);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0042470(melanosome);GO:0015991(ATP hydrolysis coupled proton transport);GO:0016820(hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances);GO:0033180(proton-transporting V-type ATPase, V1 domain);GO:0046034(ATP metabolic process);GO:0001726(ruffle);GO:0005737(cytoplasm);GO:0005902(microvillus);GO:0016021(integral component of membrane);GO:0043209(myelin sheath);GO:0070062(extracellular exosome);GO:0034220(ion transmembrane transport);GO:0012505(endomembrane system);GO:0046961(proton-transporting ATPase activity, rotational mechanism);GO:0008286(insulin receptor signaling pathway);GO:0016241(regulation of macroautophagy);GO:0033572(transferrin transport);GO:0090383(phagosome acidification);GO:0015078(hydrogen ion transmembrane transporter activity);GO:0015078(hydrogen ion transmembrane transporter activity)","00190(Oxidative phosphorylation);04150(mTOR signaling pathway);04145(Phagosome);04966(Collecting duct acid secretion);04721(Synaptic vesicle cycle);05323(Rheumatoid arthritis);05110(Vibrio cholerae infection);05120(Epithelial cell signaling in Helicobacter pylori infection);05120(Epithelial cell signaling in Helicobacter pylori infection)","K02147","NA","ATPase H+ transporting V1 subunit B2 [Source:HGNC Symbol;Acc:HGNC:854]",{"v":11.750182850722,"d":"11.75"},{"v":29.1410607022131,"d":"29.14"},{"v":0.403217404156797,"d":"0.40"},{"v":-1.31037018335905,"d":"-1.31"},{"v":0.0531434756826153,"d":"0.05"},{"v":0.679062312291212,"d":"0.68"},"down","no"]
["MSTRG.10706","DPH3","ENST00000488423;ENST00000462982;ENST00000383775;ENST00000285082","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0005515(protein binding);GO:0017183(peptidyl-diphthamide biosynthetic process from peptidyl-histidine);GO:0051099(positive regulation of binding);GO:0050709(negative regulation of protein secretion);GO:0050709(negative regulation of protein secretion)","NA","NA","NA","diphthamide biosynthesis 3 [Source:HGNC Symbol;Acc:HGNC:27717]",{"v":1.18180795901179,"d":"1.18"},{"v":0.480770236103313,"d":"0.48"},{"v":2.45815541450829,"d":"2.46"},{"v":1.29757613159843,"d":"1.30"},{"v":0.0531465171864925,"d":"0.05"},{"v":0.679062312291212,"d":"0.68"},"up","no"]
["MSTRG.12687","MYLIP","ENST00000349606;ENST00000356840","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0046872(metal ion binding);GO:0016740(transferase activity);GO:0016567(protein ubiquitination);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0008092(cytoskeletal protein binding);GO:0007399(nervous system development);GO:0061630(ubiquitin protein ligase activity);GO:0005829(cytosol);GO:0005622(intracellular);GO:0000209(protein polyubiquitination);GO:0042787(protein ubiquitination involved in ubiquitin-dependent protein catabolic process);GO:0004842(ubiquitin-protein transferase activity);GO:0006928(movement of cell or subcellular component);GO:0032802(low-density lipoprotein particle receptor catabolic process);GO:0010989(negative regulation of low-density lipoprotein particle clearance);GO:0031648(protein destabilization);GO:0032803(regulation of low-density lipoprotein particle receptor catabolic process);GO:0042632(cholesterol homeostasis);GO:0045732(positive regulation of protein catabolic process);GO:0005856(cytoskeleton);GO:0005856(cytoskeleton)","04979(Cholesterol metabolism);04979(Cholesterol metabolism)","K10637","EC:2.3.2.27","myosin regulatory light chain interacting protein [Source:HGNC Symbol;Acc:HGNC:21155]",{"v":6.88904370590175,"d":"6.89"},{"v":17.1186384272997,"d":"17.12"},{"v":0.40242941838853,"d":"0.40"},{"v":-1.31319232202047,"d":"-1.31"},{"v":0.0531532166464661,"d":"0.05"},{"v":0.679062312291212,"d":"0.68"},"down","no"]
["ENSG00000160208","RRP1B","ENST00000340648;ENST00000470886","GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005730(nucleolus);GO:0005829(cytosol);GO:0006364(rRNA processing);GO:0030687(preribosome, large subunit precursor);GO:0010923(negative regulation of phosphatase activity);GO:0030688(preribosome, small subunit precursor);GO:0000791(euchromatin);GO:0000792(heterochromatin);GO:0000792(heterochromatin)","NA","NA","NA","ribosomal RNA processing 1B [Source:HGNC Symbol;Acc:HGNC:23818]",{"v":4.95876241617494,"d":"4.96"},{"v":2.06648593127386,"d":"2.07"},{"v":2.39961102136232,"d":"2.40"},{"v":1.26280056290347,"d":"1.26"},{"v":0.0531875458572942,"d":"0.05"},{"v":0.679062312291212,"d":"0.68"},"up","no"]
["MSTRG.1220","RFWD2","ENST00000308769;ENST00000367669;ENST00000461830;ENST00000491600;ENST00000367666;ENST00000498306;ENST00000474194;ENST00000459744;ENST00000367667","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016607(nuclear speck);GO:0046872(metal ion binding);GO:0016740(transferase activity);GO:0016567(protein ubiquitination);GO:0005515(protein binding);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0043687(post-translational protein modification);GO:0043161(proteasome-mediated ubiquitin-dependent protein catabolic process);GO:0004842(ubiquitin-protein transferase activity);GO:0061630(ubiquitin protein ligase activity);GO:0032436(positive regulation of proteasomal ubiquitin-dependent protein catabolic process);GO:0010212(response to ionizing radiation);GO:0031464(Cul4A-RING E3 ubiquitin ligase complex);GO:0000139(Golgi membrane);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016021(integral component of membrane)","04120(Ubiquitin mediated proteolysis);04115(p53 signaling pathway);04115(p53 signaling pathway)","K10143","EC:2.3.2.27","ring finger and WD repeat domain 2 [Source:HGNC Symbol;Acc:HGNC:17440]",{"v":3.52575644568504,"d":"3.53"},{"v":8.76360870434985,"d":"8.76"},{"v":0.402317876645384,"d":"0.40"},{"v":-1.31359225059858,"d":"-1.31"},{"v":0.0532487585849592,"d":"0.05"},{"v":0.679062312291212,"d":"0.68"},"down","no"]
["ENSG00000175455","CCDC14","ENST00000419247;ENST00000471054;ENST00000489746;ENST00000488653;ENST00000485727;ENST00000409657;ENST00000426152;ENST00000409697;ENST00000477268;ENST00000495381;ENST00000438440","GO:0005737(cytoplasm);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0005813(centrosome);GO:0005815(microtubule organizing center);GO:0021762(substantia nigra development);GO:0034451(centriolar satellite);GO:0071539(protein localization to centrosome);GO:0071539(protein localization to centrosome)","NA","NA","NA","coiled-coil domain containing 14 [Source:HGNC Symbol;Acc:HGNC:25766]",{"v":1.24790461402434,"d":"1.25"},{"v":0.515032387726517,"d":"0.52"},{"v":2.42296337815357,"d":"2.42"},{"v":1.27677259935983,"d":"1.28"},{"v":0.0533156166793662,"d":"0.05"},{"v":0.679062312291212,"d":"0.68"},"up","no"]
["MSTRG.14929",null,"MSTRG.14929.1","NA","NA","NA","NA",null,{"v":2.128495,"d":"2.13"},{"v":5.460187,"d":"5.46"},{"v":0.389820898075469,"d":"0.39"},{"v":-1.35911666016206,"d":"-1.36"},{"v":0.0533562534734304,"d":"0.05"},{"v":0.679062312291212,"d":"0.68"},"down","no"]
["MSTRG.15237","RPGR","ENST00000339363;ENST00000482855;ENST00000474584;ENST00000318842;ENST00000470183;ENST00000476559;ENST00000378505;ENST00000494707","GO:0003723(RNA binding);GO:0005737(cytoplasm);GO:0005794(Golgi apparatus);GO:0007601(visual perception);GO:0043547(positive regulation of GTPase activity);GO:0005856(cytoskeleton);GO:0042995(cell projection);GO:0005515(protein binding);GO:0060271(cilium assembly);GO:0050896(response to stimulus);GO:0005085(guanyl-nucleotide exchange factor activity);GO:0005813(centrosome);GO:0005815(microtubule organizing center);GO:0042073(intraciliary transport);GO:0005929(cilium);GO:0030030(cell projection organization);GO:0036064(ciliary basal body);GO:0001750(photoreceptor outer segment);GO:0006886(intracellular protein transport);GO:0036126(sperm flagellum);GO:0036126(sperm flagellum)","NA","NA","NA","retinitis pigmentosa GTPase regulator [Source:HGNC Symbol;Acc:HGNC:10295]",{"v":0.527744580568389,"d":"0.53"},{"v":1.33090782962341,"d":"1.33"},{"v":0.396529773754294,"d":"0.40"},{"v":-1.33449889898335,"d":"-1.33"},{"v":0.0534297903186976,"d":"0.05"},{"v":0.679062312291212,"d":"0.68"},"down","no"]
["MSTRG.14341","HGSNAT","ENST00000379644;ENST00000519000;ENST00000519705;ENST00000520678;ENST00000520704;ENST00000521576;ENST00000524016;ENST00000523989;MSTRG.14341.9","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016740(transferase activity);GO:0005765(lysosomal membrane);GO:0016746(transferase activity, transferring acyl groups);GO:0005764(lysosome);GO:0005886(plasma membrane);GO:0043312(neutrophil degranulation);GO:0035579(specific granule membrane);GO:0070821(tertiary granule membrane);GO:0051259(protein oligomerization);GO:0006027(glycosaminoglycan catabolic process);GO:0007041(lysosomal transport);GO:0015019(heparan-alpha-glucosaminide N-acetyltransferase activity);GO:0015019(heparan-alpha-glucosaminide N-acetyltransferase activity)","00531(Glycosaminoglycan degradation);04142(Lysosome);04142(Lysosome)","K10532","EC:2.3.1.78","heparan-alpha-glucosaminide N-acetyltransferase [Source:HGNC Symbol;Acc:HGNC:26527]",{"v":1.14966218170636,"d":"1.15"},{"v":2.86862018204182,"d":"2.87"},{"v":0.400771837590592,"d":"0.40"},{"v":-1.3191469615935,"d":"-1.32"},{"v":0.0534588168121632,"d":"0.05"},{"v":0.679062312291212,"d":"0.68"},"down","no"]
["ENSG00000173482","PTPRM","ENST00000580170;ENST00000332175;ENST00000578916;ENST00000577827","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016787(hydrolase activity);GO:0007155(cell adhesion);GO:0005886(plasma membrane);GO:0004725(protein tyrosine phosphatase activity);GO:0016791(phosphatase activity);GO:0006470(protein dephosphorylation);GO:0016311(dephosphorylation);GO:0035335(peptidyl-tyrosine dephosphorylation);GO:0004721(phosphoprotein phosphatase activity);GO:0005515(protein binding);GO:0007165(signal transduction);GO:0048471(perinuclear region of cytoplasm);GO:0042802(identical protein binding);GO:0005887(integral component of plasma membrane);GO:0010842(retina layer formation);GO:0005911(cell-cell junction);GO:0001937(negative regulation of endothelial cell proliferation);GO:0010596(negative regulation of endothelial cell migration);GO:0016525(negative regulation of angiogenesis);GO:0045296(cadherin binding);GO:0007156(homophilic cell adhesion via plasma membrane adhesion molecules);GO:0030027(lamellipodium);GO:0031175(neuron projection development);GO:0005913(cell-cell adherens junction);GO:0042493(response to drug);GO:0031290(retinal ganglion cell axon guidance);GO:0005001(transmembrane receptor protein tyrosine phosphatase activity);GO:0005001(transmembrane receptor protein tyrosine phosphatase activity)","04514(Cell adhesion molecules (CAMs));04520(Adherens junction);04520(Adherens junction)","K05693","EC:3.1.3.48","protein tyrosine phosphatase, receptor type M [Source:HGNC Symbol;Acc:HGNC:9675]",{"v":0.673762207676768,"d":"0.67"},{"v":0.276645641515152,"d":"0.28"},{"v":2.43547017038353,"d":"2.44"},{"v":1.28420031317085,"d":"1.28"},{"v":0.0535704652162114,"d":"0.05"},{"v":0.679116543804171,"d":"0.68"},"up","no"]
["MSTRG.11787","LEF1","MSTRG.11787.1","NA","NA","NA","NA",null,{"v":7.502793,"d":"7.50"},{"v":2.995967,"d":"3.00"},{"v":2.50429761075472,"d":"2.50"},{"v":1.32440602235291,"d":"1.32"},{"v":0.0537000439433454,"d":"0.05"},{"v":0.679116543804171,"d":"0.68"},"up","no"]
["ENSG00000251247","ZNF345","ENST00000614069;ENST00000529555;ENST00000589046;ENST00000420450;ENST00000586646;ENST00000586933","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0006366(transcription from RNA polymerase II promoter);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0006359(regulation of transcription from RNA polymerase III promoter);GO:0006383(transcription from RNA polymerase III promoter);GO:0006383(transcription from RNA polymerase III promoter)","NA","NA","NA","zinc finger protein 345 [Source:HGNC Symbol;Acc:HGNC:16367]",{"v":0.464900939636978,"d":"0.46"},{"v":0.178909093077248,"d":"0.18"},{"v":2.59853164330919,"d":"2.60"},{"v":1.37769662735959,"d":"1.38"},{"v":0.053722054579133,"d":"0.05"},{"v":0.679116543804171,"d":"0.68"},"up","no"]
["MSTRG.13738","TMEM120A","ENST00000493111;ENST00000440632;ENST00000439537;ENST00000465989;ENST00000493251;ENST00000490656;ENST00000417509;ENST00000460127;ENST00000480538;ENST00000484946","GO:0005634(nucleus);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0003674(molecular_function);GO:0008150(biological_process);GO:0005575(cellular_component);GO:0045444(fat cell differentiation);GO:0051291(protein heterooligomerization);GO:0005637(nuclear inner membrane);GO:0051260(protein homooligomerization);GO:0051260(protein homooligomerization)","NA","NA","NA","transmembrane protein 120A [Source:HGNC Symbol;Acc:HGNC:21697]",{"v":7.41624798948423,"d":"7.42"},{"v":18.4125922248373,"d":"18.41"},{"v":0.402781308515605,"d":"0.40"},{"v":-1.31193135974904,"d":"-1.31"},{"v":0.0537657021262164,"d":"0.05"},{"v":0.679116543804171,"d":"0.68"},"down","no"]
["ENSG00000122550","KLHL7","ENST00000339077;ENST00000521082;ENST00000491352;ENST00000469845;ENST00000477076;ENST00000409689;ENST00000414163;ENST00000322275","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0016567(protein ubiquitination);GO:0005886(plasma membrane);GO:0042803(protein homodimerization activity);GO:0005515(protein binding);GO:0048471(perinuclear region of cytoplasm);GO:0031463(Cul3-RING ubiquitin ligase complex);GO:0042802(identical protein binding);GO:0004842(ubiquitin-protein transferase activity);GO:0005730(nucleolus);GO:0005730(nucleolus)","NA","NA","NA","kelch like family member 7 [Source:HGNC Symbol;Acc:HGNC:15646]",{"v":0.345585035663742,"d":"0.35"},{"v":0.876091304840079,"d":"0.88"},{"v":0.394462350846896,"d":"0.39"},{"v":-1.34204048498698,"d":"-1.34"},{"v":0.0537715087349883,"d":"0.05"},{"v":0.679116543804171,"d":"0.68"},"down","no"]
["ENSG00000134369","NAV1","ENST00000367302;ENST00000469130;ENST00000593583;ENST00000367295;ENST00000367296","GO:0005737(cytoplasm);GO:0005856(cytoskeleton);GO:0007275(multicellular organism development);GO:0007399(nervous system development);GO:0030154(cell differentiation);GO:0005874(microtubule);GO:0001578(microtubule bundle formation);GO:0001764(neuron migration);GO:0015630(microtubule cytoskeleton);GO:0043194(axon initial segment);GO:0043194(axon initial segment)","NA","NA","NA","neuron navigator 1 [Source:HGNC Symbol;Acc:HGNC:15989]",{"v":0.205908783859618,"d":"0.21"},{"v":0.0836122077673362,"d":"0.08"},{"v":2.46266411757229,"d":"2.46"},{"v":1.30021987227175,"d":"1.30"},{"v":0.053870460727588,"d":"0.05"},{"v":0.679116543804171,"d":"0.68"},"up","no"]
["ENSG00000181450","ZNF678","ENST00000440339;ENST00000343776;ENST00000397097;ENST00000465266;ENST00000608949","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0005622(intracellular);GO:0005622(intracellular)","NA","NA","NA","zinc finger protein 678 [Source:HGNC Symbol;Acc:HGNC:28652]",{"v":0.139078853393158,"d":"0.14"},{"v":0.362054806393718,"d":"0.36"},{"v":0.384137569608498,"d":"0.38"},{"v":-1.38030502495939,"d":"-1.38"},{"v":0.0539035647504,"d":"0.05"},{"v":0.679116543804171,"d":"0.68"},"down","no"]
["MSTRG.8602","CCDC121","ENST00000324364;ENST00000394775;ENST00000522876","GO:0005515(protein binding);GO:0005515(protein binding)","NA","NA","NA","coiled-coil domain containing 121 [Source:HGNC Symbol;Acc:HGNC:25833]",{"v":0.268396988045007,"d":"0.27"},{"v":0.69928214838256,"d":"0.70"},{"v":0.383817874753144,"d":"0.38"},{"v":-1.38150619414816,"d":"-1.38"},{"v":0.0539142514430151,"d":"0.05"},{"v":0.679116543804171,"d":"0.68"},"down","no"]
["MSTRG.11079","MTRNR2L12","ENST00000600213","GO:0005737(cytoplasm);GO:0005576(extracellular region)","NA","NA","NA","MT-RNR2-like 12 [Source:HGNC Symbol;Acc:HGNC:37169]",{"v":3.035611,"d":"3.04"},{"v":7.589986,"d":"7.59"},{"v":0.399949486072833,"d":"0.40"},{"v":-1.32211029687282,"d":"-1.32"},{"v":0.0544519116766188,"d":"0.05"},{"v":0.685172330626796,"d":"0.69"},"down","no"]
["ENSG00000120262","CCDC170","ENST00000239374;ENST00000537358;ENST00000544131","GO:0005515(protein binding);GO:0005515(protein binding)","NA","NA","NA","coiled-coil domain containing 170 [Source:HGNC Symbol;Acc:HGNC:21177]",{"v":0.367091205203912,"d":"0.37"},{"v":0.146417527034508,"d":"0.15"},{"v":2.50715343059575,"d":"2.51"},{"v":1.3260502876702,"d":"1.33"},{"v":0.0545778380501633,"d":"0.05"},{"v":0.685503533150193,"d":"0.69"},"up","no"]
["MSTRG.3892","SAP18","ENST00000621421;ENST00000382533;ENST00000607003;ENST00000467636;ENST00000471009;ENST00000450573;ENST00000485646;ENST00000492245","GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0016604(nuclear body);GO:0003723(RNA binding);GO:0006397(mRNA processing);GO:0008380(RNA splicing);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016607(nuclear speck);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0016575(histone deacetylation);GO:0005515(protein binding);GO:1903507(negative regulation of nucleic acid-templated transcription);GO:0043065(positive regulation of apoptotic process);GO:0003714(transcription corepressor activity);GO:0035145(exon-exon junction complex);GO:0004407(histone deacetylase activity);GO:0000381(regulation of alternative mRNA splicing, via spliceosome);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0048025(negative regulation of mRNA splicing, via spliceosome);GO:0000118(histone deacetylase complex);GO:0061574(ASAP complex);GO:0061574(ASAP complex)","03013(RNA transport);03015(mRNA surveillance pathway);03015(mRNA surveillance pathway)","K14324","NA","Sin3A associated protein 18 [Source:HGNC Symbol;Acc:HGNC:10530]",{"v":11.8242568006478,"d":"11.82"},{"v":4.95551343345112,"d":"4.96"},{"v":2.38608107100078,"d":"2.39"},{"v":1.25464306178578,"d":"1.25"},{"v":0.0546495283806928,"d":"0.05"},{"v":0.685503533150193,"d":"0.69"},"up","no"]
["MSTRG.8798","FAM136A","ENST00000037869;ENST00000460307;ENST00000498665;ENST00000438759;ENST00000430566","GO:0005737(cytoplasm);GO:0005737(cytoplasm)","NA","NA","NA","family with sequence similarity 136 member A [Source:HGNC Symbol;Acc:HGNC:25911]",{"v":1.16322225113415,"d":"1.16"},{"v":2.92927938010369,"d":"2.93"},{"v":0.397101846629929,"d":"0.40"},{"v":-1.33241902509109,"d":"-1.33"},{"v":0.0546702398054163,"d":"0.05"},{"v":0.685503533150193,"d":"0.69"},"down","no"]
["ENSG00000211786","TRAV8-2","ENST00000390434","NA","NA","NA","NA","T-cell receptor alpha variable 8-2 [Source:HGNC Symbol;Acc:HGNC:12147]",{"v":6.332118,"d":"6.33"},{"v":2.586095,"d":"2.59"},{"v":2.44852489951065,"d":"2.45"},{"v":1.29191286715874,"d":"1.29"},{"v":0.0547628567697926,"d":"0.05"},{"v":0.685503533150193,"d":"0.69"},"up","no"]
["MSTRG.13718","NCF1C","ENST00000438382","NA","NA","NA","NA","neutrophil cytosolic factor 1C pseudogene [Source:HGNC Symbol;Acc:HGNC:32523]",{"v":47.583813,"d":"47.58"},{"v":117.314705,"d":"117.31"},{"v":0.405608256867713,"d":"0.41"},{"v":-1.3018410736584,"d":"-1.30"},{"v":0.0547750143694237,"d":"0.05"},{"v":0.685503533150193,"d":"0.69"},"down","no"]
["ENSG00000084444","FAM234B","ENST00000197268;ENST00000535974;ENST00000416494;ENST00000540455","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016021(integral component of membrane)","NA","NA","NA","family with sequence similarity 234 member B [Source:HGNC Symbol;Acc:HGNC:29288]",{"v":0.493500387689144,"d":"0.49"},{"v":0.20213600058763,"d":"0.20"},{"v":2.4414274857249,"d":"2.44"},{"v":1.28772492827695,"d":"1.29"},{"v":0.054819789272848,"d":"0.05"},{"v":0.685503533150193,"d":"0.69"},"up","no"]
["ENSG00000112053","SLC26A8","ENST00000490799;ENST00000466805;ENST00000486155;ENST00000465492","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0055085(transmembrane transport);GO:0030317(flagellated sperm motility);GO:0006811(ion transport);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0007275(multicellular organism development);GO:0051321(meiotic cell cycle);GO:0030154(cell differentiation);GO:0005254(chloride channel activity);GO:0006821(chloride transport);GO:1902476(chloride transmembrane transport);GO:0008271(secondary active sulfate transmembrane transporter activity);GO:0008509(anion transmembrane transporter activity);GO:0015116(sulfate transmembrane transporter activity);GO:0006820(anion transport);GO:0007283(spermatogenesis);GO:0008272(sulfate transport);GO:0048240(sperm capacitation);GO:0098656(anion transmembrane transport);GO:1902358(sulfate transmembrane transport);GO:0005887(integral component of plasma membrane);GO:0015106(bicarbonate transmembrane transporter activity);GO:0015301(anion:anion antiporter activity);GO:0015701(bicarbonate transport);GO:0042391(regulation of membrane potential);GO:0051453(regulation of intracellular pH);GO:0019531(oxalate transmembrane transporter activity);GO:0019532(oxalate transport);GO:0019532(oxalate transport)","NA","NA","NA","solute carrier family 26 member 8 [Source:HGNC Symbol;Acc:HGNC:14468]",{"v":0.149001972498343,"d":"0.15"},{"v":0.38055469267727,"d":"0.38"},{"v":0.391538917704805,"d":"0.39"},{"v":-1.35277238101281,"d":"-1.35"},{"v":0.0548887432064302,"d":"0.05"},{"v":0.685653781838001,"d":"0.69"},"down","no"]
["ENSG00000166963","MAP1A","ENST00000382031;ENST00000300231","GO:0008017(microtubule binding);GO:0000226(microtubule cytoskeleton organization);GO:0005874(microtubule);GO:0005737(cytoplasm);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0005875(microtubule associated complex);GO:0005198(structural molecule activity);GO:0005198(structural molecule activity)","NA","NA","NA","microtubule associated protein 1A [Source:HGNC Symbol;Acc:HGNC:6835]",{"v":0.757797536456863,"d":"0.76"},{"v":0.315334045065387,"d":"0.32"},{"v":2.40315801073661,"d":"2.40"},{"v":1.26493151064488,"d":"1.26"},{"v":0.054993054136263,"d":"0.05"},{"v":0.686244930475522,"d":"0.69"},"up","no"]
["ENSG00000255274","TMPRSS4-AS1","ENST00000636151","GO:0016020(membrane);GO:0016021(integral component of membrane)","NA","NA","NA","TMPRSS4 antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:44179]",{"v":0.497245451313346,"d":"0.50"},{"v":0.195324345449721,"d":"0.20"},{"v":2.54574231475586,"d":"2.55"},{"v":1.34808639408671,"d":"1.35"},{"v":0.0550874255960314,"d":"0.06"},{"v":0.68634378458934,"d":"0.69"},"up","no"]
["MSTRG.14791",null,"MSTRG.14791.1","NA","NA","NA","NA",null,{"v":2.15262,"d":"2.15"},{"v":5.596111,"d":"5.60"},{"v":0.384663563678419,"d":"0.38"},{"v":-1.37833091456396,"d":"-1.38"},{"v":0.0551149675882654,"d":"0.06"},{"v":0.68634378458934,"d":"0.69"},"down","no"]
["MSTRG.1389","TATDN3","ENST00000366973;ENST00000366974;ENST00000530392;ENST00000525569;ENST00000606486;ENST00000526641;ENST00000531963;ENST00000530399;ENST00000532324;ENST00000532433;ENST00000497768","GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0016787(hydrolase activity);GO:0090305(nucleic acid phosphodiester bond hydrolysis);GO:0016788(hydrolase activity, acting on ester bonds);GO:0004518(nuclease activity);GO:0004518(nuclease activity)","NA","NA","NA","TatD DNase domain containing 3 [Source:HGNC Symbol;Acc:HGNC:27010]",{"v":0.329915884107709,"d":"0.33"},{"v":0.850666014255544,"d":"0.85"},{"v":0.387832449608832,"d":"0.39"},{"v":-1.36649457733434,"d":"-1.37"},{"v":0.0552955337519351,"d":"0.06"},{"v":0.687881009752895,"d":"0.69"},"down","no"]
["MSTRG.12865","NCR3","ENST00000340027;ENST00000376073;ENST00000376071;ENST00000495600;ENST00000491161;ENST00000376072","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0006955(immune response);GO:0002376(immune system process);GO:0006954(inflammatory response);GO:0050776(regulation of immune response);GO:0005887(integral component of plasma membrane);GO:0030101(natural killer cell activation);GO:0004872(receptor activity);GO:0005102(receptor binding);GO:0042803(protein homodimerization activity);GO:0050839(cell adhesion molecule binding);GO:0002429(immune response-activating cell surface receptor signaling pathway);GO:0002860(positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target);GO:0007156(homophilic cell adhesion via plasma membrane adhesion molecules);GO:0007157(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules);GO:0008037(cell recognition);GO:0042271(susceptibility to natural killer cell mediated cytotoxicity);GO:0045954(positive regulation of natural killer cell mediated cytotoxicity);GO:0060370(susceptibility to T cell mediated cytotoxicity);GO:0005913(cell-cell adherens junction);GO:0005913(cell-cell adherens junction)","04650(Natural killer cell mediated cytotoxicity);04650(Natural killer cell mediated cytotoxicity)","K06743","NA","natural cytotoxicity triggering receptor 3 [Source:HGNC Symbol;Acc:HGNC:19077]",{"v":10.2015099158416,"d":"10.20"},{"v":4.2627068209571,"d":"4.26"},{"v":2.39319998872244,"d":"2.39"},{"v":1.25894096130704,"d":"1.26"},{"v":0.0555024471685772,"d":"0.06"},{"v":0.689349247413219,"d":"0.69"},"up","no"]
["MSTRG.1244","NPL","MSTRG.1244.4;ENST00000367553;ENST00000367554;MSTRG.1244.5;ENST00000258317;ENST00000463899;ENST00000471010;ENST00000460179;ENST00000488424;ENST00000367555;ENST00000460690;ENST00000614468;ENST00000479721;ENST00000367552","GO:0005737(cytoplasm);GO:0003824(catalytic activity);GO:0016829(lyase activity);GO:0008152(metabolic process);GO:0005975(carbohydrate metabolic process);GO:0005515(protein binding);GO:0042802(identical protein binding);GO:0005829(cytosol);GO:0019262(N-acetylneuraminate catabolic process);GO:0008747(N-acetylneuraminate lyase activity);GO:0008747(N-acetylneuraminate lyase activity)","00520(Amino sugar and nucleotide sugar metabolism);00520(Amino sugar and nucleotide sugar metabolism)","K01639","EC:4.1.3.3","N-acetylneuraminate pyruvate lyase [Source:HGNC Symbol;Acc:HGNC:16781]",{"v":4.69639757012962,"d":"4.70"},{"v":11.5811932162894,"d":"11.58"},{"v":0.405519317605716,"d":"0.41"},{"v":-1.30215745356404,"d":"-1.30"},{"v":0.0555280493265922,"d":"0.06"},{"v":0.689349247413219,"d":"0.69"},"down","no"]
["MSTRG.9498","TIGD1","ENST00000408957","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0003677(DNA binding)","NA","NA","NA","tigger transposable element derived 1 [Source:HGNC Symbol;Acc:HGNC:14523]",{"v":0.469374,"d":"0.47"},{"v":1.19352,"d":"1.19"},{"v":0.393268650713855,"d":"0.39"},{"v":-1.34641290800205,"d":"-1.35"},{"v":0.0556443855415996,"d":"0.06"},{"v":0.6895272567792,"d":"0.69"},"down","no"]
["MSTRG.11282","P2RY13","ENST00000325602;MSTRG.11282.1","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0004930(G-protein coupled receptor activity);GO:0007186(G-protein coupled receptor signaling pathway);GO:0005886(plasma membrane);GO:0004871(signal transducer activity);GO:0007165(signal transduction);GO:0045028(G-protein coupled purinergic nucleotide receptor activity);GO:0035589(G-protein coupled purinergic nucleotide receptor signaling pathway);GO:0005887(integral component of plasma membrane);GO:0008150(biological_process);GO:0007194(negative regulation of adenylate cyclase activity);GO:0071407(cellular response to organic cyclic compound);GO:0005783(endoplasmic reticulum)","04080(Neuroactive ligand-receptor interaction)","K08388","NA","purinergic receptor P2Y13 [Source:HGNC Symbol;Acc:HGNC:4537]",{"v":26.3380792492091,"d":"26.34"},{"v":64.7163674094903,"d":"64.72"},{"v":0.40697709564809,"d":"0.41"},{"v":-1.29698049185712,"d":"-1.30"},{"v":0.0556569086189489,"d":"0.06"},{"v":0.6895272567792,"d":"0.69"},"down","no"]
["ENSG00000235823","OLMALINC","ENST00000641087;ENST00000641708;ENST00000454935","NA","NA","NA","NA","oligodendrocyte maturation-associated long intergenic non-coding RNA [Source:HGNC Symbol;Acc:HGNC:28060]",{"v":0.243886722787582,"d":"0.24"},{"v":0.0972216676542574,"d":"0.10"},{"v":2.50856345783842,"d":"2.51"},{"v":1.32686143367759,"d":"1.33"},{"v":0.0557792908366574,"d":"0.06"},{"v":0.690333217117192,"d":"0.69"},"up","no"]
["MSTRG.756","TMEM167B","ENST00000338272;ENST00000473828;ENST00000479160","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005794(Golgi apparatus);GO:0000139(Golgi membrane);GO:0012505(endomembrane system);GO:0009306(protein secretion);GO:0046907(intracellular transport);GO:0046907(intracellular transport)","NA","NA","NA","transmembrane protein 167B [Source:HGNC Symbol;Acc:HGNC:30187]",{"v":3.62986348185396,"d":"3.63"},{"v":8.93119540030608,"d":"8.93"},{"v":0.406425267745185,"d":"0.41"},{"v":-1.29893799662208,"d":"-1.30"},{"v":0.0558889932464482,"d":"0.06"},{"v":0.690980756338532,"d":"0.69"},"down","no"]
["ENSG00000174123","TLR10","ENST00000507953;ENST00000361424;ENST00000508334;ENST00000613579;ENST00000308973;ENST00000506111;ENST00000622002","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0007165(signal transduction);GO:0006955(immune response);GO:0004888(transmembrane signaling receptor activity);GO:0002376(immune system process);GO:0002755(MyD88-dependent toll-like receptor signaling pathway);GO:0034166(toll-like receptor 10 signaling pathway);GO:0045087(innate immune response);GO:0050707(regulation of cytokine secretion);GO:0050729(positive regulation of inflammatory response);GO:0006954(inflammatory response);GO:0005886(plasma membrane);GO:0005887(integral component of plasma membrane);GO:0002224(toll-like receptor signaling pathway);GO:0002224(toll-like receptor signaling pathway)","NA","NA","NA","toll like receptor 10 [Source:HGNC Symbol;Acc:HGNC:15634]",{"v":0.483100110030828,"d":"0.48"},{"v":1.20516164737965,"d":"1.21"},{"v":0.400859180244591,"d":"0.40"},{"v":-1.31883258050924,"d":"-1.32"},{"v":0.0560178259288319,"d":"0.06"},{"v":0.691863240856404,"d":"0.69"},"down","no"]
["MSTRG.12185","ARRDC3","ENST00000265138;ENST00000511391;ENST00000505631;ENST00000514284;ENST00000507075;ENST00000508948;ENST00000503192","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0005764(lysosome);GO:0005768(endosome);GO:0005769(early endosome);GO:0051443(positive regulation of ubiquitin-protein transferase activity);GO:0031699(beta-3 adrenergic receptor binding);GO:0001659(temperature homeostasis);GO:0031651(negative regulation of heat generation);GO:0043588(skin development);GO:0044252(negative regulation of multicellular organismal metabolic process);GO:0060613(fat pad development);GO:0071879(positive regulation of adrenergic receptor signaling pathway);GO:0090327(negative regulation of locomotion involved in locomotory behavior);GO:0090327(negative regulation of locomotion involved in locomotory behavior)","NA","NA","NA","arrestin domain containing 3 [Source:HGNC Symbol;Acc:HGNC:29263]",{"v":17.6767359239968,"d":"17.68"},{"v":43.3523606520065,"d":"43.35"},{"v":0.407745637334253,"d":"0.41"},{"v":-1.29425865395243,"d":"-1.29"},{"v":0.0561398108490565,"d":"0.06"},{"v":0.692659428529036,"d":"0.69"},"down","no"]
["ENSG00000227946","AC007383.2","ENST00000420509","NA","NA","NA","NA",null,{"v":2.18935781818182,"d":"2.19"},{"v":0.877854545454545,"d":"0.88"},{"v":2.49398699308231,"d":"2.49"},{"v":1.31845394108395,"d":"1.32"},{"v":0.0562778296270275,"d":"0.06"},{"v":0.693223115011385,"d":"0.69"},"up","no"]
["ENSG00000067208","EVI5","ENST00000540033;ENST00000370331;ENST00000492513;ENST00000474806;ENST00000492613;ENST00000466778;ENST00000491940","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0051301(cell division);GO:0005829(cytosol);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0005096(GTPase activator activity);GO:0007049(cell cycle);GO:0043087(regulation of GTPase activity);GO:0005815(microtubule organizing center);GO:0005819(spindle);GO:0006886(intracellular protein transport);GO:0031338(regulation of vesicle fusion);GO:0090630(activation of GTPase activity);GO:0012505(endomembrane system);GO:0043547(positive regulation of GTPase activity);GO:0042147(retrograde transport, endosome to Golgi);GO:0007275(multicellular organism development);GO:0008283(cell proliferation);GO:0017137(Rab GTPase binding);GO:0017137(Rab GTPase binding)","NA","NA","NA","ecotropic viral integration site 5 [Source:HGNC Symbol;Acc:HGNC:3501]",{"v":0.304353732479459,"d":"0.30"},{"v":0.765559058482359,"d":"0.77"},{"v":0.397557483132403,"d":"0.40"},{"v":-1.33076461905826,"d":"-1.33"},{"v":0.0563006316626087,"d":"0.06"},{"v":0.693223115011385,"d":"0.69"},"down","no"]
["MSTRG.14977","TOR2A","ENST00000373284;ENST00000472723;ENST00000493439;ENST00000494135;ENST00000336067;ENST00000463577;ENST00000373281;ENST00000496460;ENST00000463256","GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0005576(extracellular region);GO:0005179(hormone activity);GO:0005783(endoplasmic reticulum);GO:0005788(endoplasmic reticulum lumen);GO:0051085(chaperone mediated protein folding requiring cofactor);GO:0051260(protein homooligomerization);GO:0051260(protein homooligomerization)","NA","NA","NA","torsin family 2 member A [Source:HGNC Symbol;Acc:HGNC:11996]",{"v":1.54227718555614,"d":"1.54"},{"v":3.81184322324723,"d":"3.81"},{"v":0.404601421210158,"d":"0.40"},{"v":-1.30542670734597,"d":"-1.31"},{"v":0.0563667301030211,"d":"0.06"},{"v":0.693328053013871,"d":"0.69"},"down","no"]
["ENSG00000075275","CELSR1","ENST00000262738;ENST00000454637;ENST00000468025;ENST00000473624","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0004930(G-protein coupled receptor activity);GO:0007186(G-protein coupled receptor signaling pathway);GO:0005654(nucleoplasm);GO:0005509(calcium ion binding);GO:0007155(cell adhesion);GO:0007156(homophilic cell adhesion via plasma membrane adhesion molecules);GO:0005886(plasma membrane);GO:0004871(signal transducer activity);GO:0007165(signal transduction);GO:0004888(transmembrane signaling receptor activity);GO:0007166(cell surface receptor signaling pathway);GO:0007275(multicellular organism development);GO:0005887(integral component of plasma membrane);GO:0060071(Wnt signaling pathway, planar cell polarity pathway);GO:0001843(neural tube closure);GO:0046983(protein dimerization activity);GO:0007417(central nervous system development);GO:0001736(establishment of planar polarity);GO:0001764(neuron migration);GO:0001942(hair follicle development);GO:0007266(Rho protein signal transduction);GO:0007626(locomotory behavior);GO:0009952(anterior/posterior pattern specification);GO:0032956(regulation of actin cytoskeleton organization);GO:0042060(wound healing);GO:0042249(establishment of planar polarity of embryonic epithelium);GO:0042472(inner ear morphogenesis);GO:0045176(apical protein localization);GO:0048105(establishment of body hair planar orientation);GO:0060488(orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis);GO:0060489(planar dichotomous subdivision of terminal units involved in lung branching morphogenesis);GO:0060490(lateral sprouting involved in lung morphogenesis);GO:0090179(planar cell polarity pathway involved in neural tube closure);GO:0090251(protein localization involved in establishment of planar polarity);GO:0090251(protein localization involved in establishment of planar polarity)","NA","NA","NA","cadherin EGF LAG seven-pass G-type receptor 1 [Source:HGNC Symbol;Acc:HGNC:1850]",{"v":0.241898001093238,"d":"0.24"},{"v":0.100257173121974,"d":"0.10"},{"v":2.41277500213319,"d":"2.41"},{"v":1.27069338656847,"d":"1.27"},{"v":0.0564856578070012,"d":"0.06"},{"v":0.694081929910111,"d":"0.69"},"up","no"]
["MSTRG.8350","PTOV1-AS2","ENST00000599259;ENST00000601893;ENST00000593654","NA","NA","NA","NA","PTOV1 antisense RNA 2 [Source:HGNC Symbol;Acc:HGNC:51284]",{"v":2.28279038025415,"d":"2.28"},{"v":0.919248058651026,"d":"0.92"},{"v":2.48332358036642,"d":"2.48"},{"v":1.31227225884641,"d":"1.31"},{"v":0.0565792026585525,"d":"0.06"},{"v":0.694522689515076,"d":"0.69"},"up","no"]
["MSTRG.7794","ICAM1","ENST00000423829;ENST00000264832;ENST00000588645;ENST00000585443","GO:0005615(extracellular space);GO:0070374(positive regulation of ERK1 and ERK2 cascade);GO:2000352(negative regulation of endothelial cell apoptotic process);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0007155(cell adhesion);GO:0016337(single organismal cell-cell adhesion);GO:0005925(focal adhesion);GO:0050776(regulation of immune response);GO:0005886(plasma membrane);GO:0046718(viral entry into host cell);GO:0005515(protein binding);GO:0070062(extracellular exosome);GO:0016032(viral process);GO:0005887(integral component of plasma membrane);GO:0004872(receptor activity);GO:0009986(cell surface);GO:0061028(establishment of endothelial barrier);GO:0030198(extracellular matrix organization);GO:0060333(interferon-gamma-mediated signaling pathway);GO:0004888(transmembrane signaling receptor activity);GO:0001618(virus receptor activity);GO:1902042(negative regulation of extrinsic apoptotic signaling pathway via death domain receptors);GO:0007157(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules);GO:0005178(integrin binding);GO:0032403(protein complex binding);GO:0001541(ovarian follicle development);GO:0001666(response to hypoxia);GO:0001910(regulation of leukocyte mediated cytotoxicity);GO:0001975(response to amphetamine);GO:0002291(T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell);GO:0002438(acute inflammatory response to antigenic stimulus);GO:0002457(T cell antigen processing and presentation);GO:0002693(positive regulation of cellular extravasation);GO:0007159(leukocyte cell-cell adhesion);GO:0007569(cell aging);GO:0007605(sensory perception of sound);GO:0008360(regulation of cell shape);GO:0010212(response to ionizing radiation);GO:0010477(response to sulfur dioxide);GO:0014070(response to organic cyclic compound);GO:0022614(membrane to membrane docking);GO:0030155(regulation of cell adhesion);GO:0030838(positive regulation of actin filament polymerization);GO:0031669(cellular response to nutrient levels);GO:0032496(response to lipopolysaccharide);GO:0032868(response to insulin);GO:0033627(cell adhesion mediated by integrin);GO:0034698(response to gonadotropin);GO:0042493(response to drug);GO:0043200(response to amino acid);GO:0043547(positive regulation of GTPase activity);GO:0044406(adhesion of symbiont to host);GO:0045429(positive regulation of nitric oxide biosynthetic process);GO:0045471(response to ethanol);GO:0045907(positive regulation of vasoconstriction);GO:0046688(response to copper ion);GO:0046813(receptor-mediated virion attachment to host cell);GO:0050731(positive regulation of peptidyl-tyrosine phosphorylation);GO:0050900(leukocyte migration);GO:0051092(positive regulation of NF-kappaB transcription factor activity);GO:0051926(negative regulation of calcium ion transport);GO:0071222(cellular response to lipopolysaccharide);GO:0071310(cellular response to organic substance);GO:0071312(cellular response to alkaloid);GO:0071333(cellular response to glucose stimulus);GO:0071346(cellular response to interferon-gamma);GO:0071347(cellular response to interleukin-1);GO:0071354(cellular response to interleukin-6);GO:0071356(cellular response to tumor necrosis factor);GO:0071456(cellular response to hypoxia);GO:0071549(cellular response to dexamethasone stimulus);GO:0090557(establishment of endothelial intestinal barrier);GO:0097368(establishment of Sertoli cell barrier);GO:1900027(regulation of ruffle assembly);GO:1904996(positive regulation of leukocyte adhesion to vascular endothelial cell);GO:1990830(cellular response to leukemia inhibitory factor);GO:0001772(immunological synapse);GO:0009897(external side of plasma membrane);GO:0045121(membrane raft);GO:0045121(membrane raft)","04064(NF-kappa B signaling pathway);04668(TNF signaling pathway);04514(Cell adhesion molecules (CAMs));04650(Natural killer cell mediated cytotoxicity);04670(Leukocyte transendothelial migration);05323(Rheumatoid arthritis);05418(Fluid shear stress and atherosclerosis);05416(Viral myocarditis);04933(AGE-RAGE signaling pathway in diabetic complications);05150(Staphylococcus aureus infection);05166(HTLV-I infection);05164(Influenza A);05167(Kaposi's sarcoma-associated herpesvirus infection);05169(Epstein-Barr virus infection);05144(Malaria);05143(African trypanosomiasis);05143(African trypanosomiasis)","K06490","NA","intercellular adhesion molecule 1 [Source:HGNC Symbol;Acc:HGNC:5344]",{"v":2.74044021694549,"d":"2.74"},{"v":6.74866371775499,"d":"6.75"},{"v":0.406071532314715,"d":"0.41"},{"v":-1.30019420435984,"d":"-1.30"},{"v":0.056671817356153,"d":"0.06"},{"v":0.694817094939437,"d":"0.69"},"down","no"]
["MSTRG.6838","PSMC3IP","ENST00000587209;ENST00000589505;ENST00000590931;ENST00000587268;ENST00000588544;ENST00000393795;ENST00000253789;ENST00000586337","GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0003677(DNA binding);GO:0006310(DNA recombination);GO:1903506(regulation of nucleic acid-templated transcription);GO:0051321(meiotic cell cycle);GO:0030374(ligand-dependent nuclear receptor transcription coactivator activity);GO:0007131(reciprocal meiotic recombination);GO:0005575(cellular_component);GO:0005575(cellular_component)","NA","NA","NA","PSMC3 interacting protein [Source:HGNC Symbol;Acc:HGNC:17928]",{"v":0.660549906723669,"d":"0.66"},{"v":0.261960800621842,"d":"0.26"},{"v":2.52156011569539,"d":"2.52"},{"v":1.33431662052894,"d":"1.33"},{"v":0.0567453894600837,"d":"0.06"},{"v":0.694817094939437,"d":"0.69"},"up","no"]
["MSTRG.14545","FAM91A1","ENST00000334705;ENST00000521166;ENST00000518333;ENST00000520246;ENST00000519721;ENST00000518976;ENST00000517912","NA","NA","NA","NA","family with sequence similarity 91 member A1 [Source:HGNC Symbol;Acc:HGNC:26306]",{"v":1.46144926207563,"d":"1.46"},{"v":3.59199238490201,"d":"3.59"},{"v":0.406863129281244,"d":"0.41"},{"v":-1.29738454834958,"d":"-1.30"},{"v":0.0568607546394548,"d":"0.06"},{"v":0.694817094939437,"d":"0.69"},"down","no"]
["MSTRG.11249","C3orf58","ENST00000315691;ENST00000491798;ENST00000495414;ENST00000483808","GO:0005794(Golgi apparatus);GO:0005576(extracellular region);GO:0005615(extracellular space);GO:0031410(cytoplasmic vesicle);GO:0014066(regulation of phosphatidylinositol 3-kinase signaling);GO:0060038(cardiac muscle cell proliferation);GO:0030126(COPI vesicle coat);GO:0030137(COPI-coated vesicle);GO:0000139(Golgi membrane);GO:0000139(Golgi membrane)","NA","NA","NA","chromosome 3 open reading frame 58 [Source:HGNC Symbol;Acc:HGNC:28490]",{"v":0.776053677419355,"d":"0.78"},{"v":1.91832889374886,"d":"1.92"},{"v":0.404546728117495,"d":"0.40"},{"v":-1.30562174073693,"d":"-1.31"},{"v":0.0569227621096623,"d":"0.06"},{"v":0.694817094939437,"d":"0.69"},"down","no"]
["ENSG00000133067","LGR6","ENST00000255432;ENST00000367278;ENST00000308543;ENST00000506931;ENST00000503519;ENST00000487787","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0007186(G-protein coupled receptor signaling pathway);GO:0005886(plasma membrane);GO:0004871(signal transducer activity);GO:0007165(signal transduction);GO:0016055(Wnt signaling pathway);GO:0005887(integral component of plasma membrane);GO:0005515(protein binding);GO:0030335(positive regulation of cell migration);GO:0090263(positive regulation of canonical Wnt signaling pathway);GO:0004888(transmembrane signaling receptor activity);GO:0031982(vesicle);GO:0032588(trans-Golgi network membrane);GO:0030177(positive regulation of Wnt signaling pathway);GO:0042246(tissue regeneration);GO:1990523(bone regeneration);GO:1990523(bone regeneration)","NA","NA","NA","leucine rich repeat containing G protein-coupled receptor 6 [Source:HGNC Symbol;Acc:HGNC:19719]",{"v":2.22470676805586,"d":"2.22"},{"v":0.934474032729653,"d":"0.93"},{"v":2.3807047495556,"d":"2.38"},{"v":1.25138871142555,"d":"1.25"},{"v":0.0569229275506832,"d":"0.06"},{"v":0.694817094939437,"d":"0.69"},"up","no"]
["MSTRG.2908","KMT2A","ENST00000534358;ENST00000531904;ENST00000533790;ENST00000527869;ENST00000420751;ENST00000534678;ENST00000528278;ENST00000389506;ENST00000525408;ENST00000527839;ENST00000392873;ENST00000529852","GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0005634(nucleus);GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0008168(methyltransferase activity);GO:0016740(transferase activity);GO:0032259(methylation);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0016569(covalent chromatin modification);GO:0003677(DNA binding);GO:0042803(protein homodimerization activity);GO:0005515(protein binding);GO:0048511(rhythmic process);GO:0006915(apoptotic process);GO:0018024(histone-lysine N-methyltransferase activity);GO:0045893(positive regulation of transcription, DNA-templated);GO:0042802(identical protein binding);GO:1902036(regulation of hematopoietic stem cell differentiation);GO:0044212(transcription regulatory region DNA binding);GO:0006366(transcription from RNA polymerase II promoter);GO:0071339(MLL1 complex);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0032922(circadian regulation of gene expression);GO:0001046(core promoter sequence-specific DNA binding);GO:0042800(histone methyltransferase activity (H3-K4 specific));GO:0045652(regulation of megakaryocyte differentiation);GO:0051568(histone H3-K4 methylation);GO:2000615(regulation of histone H3-K9 acetylation);GO:0006461(protein complex assembly);GO:0035097(histone methyltransferase complex);GO:0070577(lysine-acetylated histone binding);GO:0043984(histone H4-K16 acetylation);GO:0051571(positive regulation of histone H3-K4 methylation);GO:0035162(embryonic hemopoiesis);GO:0003680(AT DNA binding);GO:0032411(positive regulation of transporter activity);GO:0003682(chromatin binding);GO:0045322(unmethylated CpG binding);GO:0006306(DNA methylation);GO:0008285(negative regulation of cell proliferation);GO:0008542(visual learning);GO:0009416(response to light stimulus);GO:0009791(post-embryonic development);GO:0009952(anterior/posterior pattern specification);GO:0010468(regulation of gene expression);GO:0018026(peptidyl-lysine monomethylation);GO:0035640(exploration behavior);GO:0035864(response to potassium ion);GO:0044648(histone H3-K4 dimethylation);GO:0048172(regulation of short-term neuronal synaptic plasticity);GO:0048536(spleen development);GO:0048873(homeostasis of number of cells within a tissue);GO:0050890(cognition);GO:0051569(regulation of histone H3-K4 methylation);GO:0051899(membrane depolarization);GO:0060216(definitive hemopoiesis);GO:0071440(regulation of histone H3-K14 acetylation);GO:0080182(histone H3-K4 trimethylation);GO:1901674(regulation of histone H3-K27 acetylation);GO:2001040(positive regulation of cellular response to drug);GO:2001040(positive regulation of cellular response to drug)","00310(Lysine degradation);05202(Transcriptional misregulation in cancers);05202(Transcriptional misregulation in cancers)","K09186","EC:2.1.1.43","lysine methyltransferase 2A [Source:HGNC Symbol;Acc:HGNC:7132]",{"v":3.60288571959383,"d":"3.60"},{"v":1.52564649351122,"d":"1.53"},{"v":2.36154688187427,"d":"2.36"},{"v":1.23973217642693,"d":"1.24"},{"v":0.0569493832175074,"d":"0.06"},{"v":0.694817094939437,"d":"0.69"},"up","no"]
["MSTRG.9724","C20orf24;TGIF2;TGIF2-C20orf24","ENST00000344795;ENST00000373872;ENST00000342422;ENST00000560025;ENST00000639924;ENST00000491113;ENST00000492721;ENST00000611732;ENST00000494506;ENST00000373852;ENST00000373874;ENST00000558530;ENST00000558028;ENST00000483815","GO:0003674(molecular_function);GO:0008150(biological_process);GO:0005575(cellular_component);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0010470(regulation of gastrulation);GO:0038092(nodal signaling pathway);GO:0045666(positive regulation of neuron differentiation);GO:0060041(retina development in camera-type eye);GO:0005739(mitochondrion);GO:0016021(integral component of membrane)","04350(TGF-beta signaling pathway);04350(TGF-beta signaling pathway)","K19553","NA","chromosome 20 open reading frame 24 [Source:HGNC Symbol;Acc:HGNC:15870];TGFB induced factor homeobox 2 [Source:HGNC Symbol;Acc:HGNC:15764];TGIF2-C20orf24 readthrough [Source:HGNC Symbol;Acc:HGNC:44664]",{"v":4.76765138207724,"d":"4.77"},{"v":11.6779586377953,"d":"11.68"},{"v":0.408260684075974,"d":"0.41"},{"v":-1.29243745365218,"d":"-1.29"},{"v":0.0570454116629059,"d":"0.06"},{"v":0.695284258344851,"d":"0.70"},"down","no"]
["MSTRG.8878","TMEM150A","ENST00000334462;ENST00000451147;ENST00000433956;ENST00000409668;ENST00000417791;ENST00000431593;ENST00000444380;ENST00000463363;ENST00000306353","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0005887(integral component of plasma membrane);GO:0005764(lysosome);GO:0090002(establishment of protein localization to plasma membrane);GO:0046854(phosphatidylinositol phosphorylation);GO:0009056(catabolic process);GO:0009056(catabolic process)","NA","NA","NA","transmembrane protein 150A [Source:HGNC Symbol;Acc:HGNC:24677]",{"v":0.705490426308985,"d":"0.71"},{"v":1.77036791338074,"d":"1.77"},{"v":0.398499329420043,"d":"0.40"},{"v":-1.32735079838352,"d":"-1.33"},{"v":0.0572876782424453,"d":"0.06"},{"v":0.697531063089511,"d":"0.70"},"down","no"]
["ENSG00000169155","ZBTB43","ENST00000373464;ENST00000450858;ENST00000449886;ENST00000373457","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0005515(protein binding)","NA","NA","NA","zinc finger and BTB domain containing 43 [Source:HGNC Symbol;Acc:HGNC:17908]",{"v":0.9977388560692,"d":"1.00"},{"v":0.41554154849688,"d":"0.42"},{"v":2.40105678885367,"d":"2.40"},{"v":1.26366952602925,"d":"1.26"},{"v":0.0575783075308809,"d":"0.06"},{"v":0.699666279303353,"d":"0.70"},"up","no"]
["MSTRG.10119","DGCR2","MSTRG.10119.3;ENST00000263196;ENST00000473832;ENST00000545799;ENST00000537045;ENST00000389262;ENST00000608548;ENST00000467659","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0030246(carbohydrate binding);GO:0007155(cell adhesion);GO:0050890(cognition);GO:0009887(animal organ morphogenesis);GO:0009887(animal organ morphogenesis)","NA","NA","NA","DiGeorge syndrome critical region gene 2 [Source:HGNC Symbol;Acc:HGNC:2845]",{"v":9.4230845837645,"d":"9.42"},{"v":22.9998623148974,"d":"23.00"},{"v":0.40970178233028,"d":"0.41"},{"v":-1.28735392588301,"d":"-1.29"},{"v":0.0575792462040876,"d":"0.06"},{"v":0.699666279303353,"d":"0.70"},"down","no"]
["ENSG00000269743","SLC25A53","ENST00000594199;ENST00000467290","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005743(mitochondrial inner membrane);GO:0005739(mitochondrion);GO:0055085(transmembrane transport);GO:0006839(mitochondrial transport);GO:0022857(transmembrane transporter activity);GO:0022857(transmembrane transporter activity)","NA","NA","NA","solute carrier family 25 member 53 [Source:HGNC Symbol;Acc:HGNC:31894]",{"v":0.944035602921841,"d":"0.94"},{"v":0.39578449963477,"d":"0.40"},{"v":2.3852263132917,"d":"2.39"},{"v":1.25412615745666,"d":"1.25"},{"v":0.0581490187022081,"d":"0.06"},{"v":0.705877503237893,"d":"0.71"},"up","no"]
["ENSG00000119953","SMNDC1","ENST00000369603;ENST00000477763;ENST00000460483;ENST00000471297;ENST00000369592","GO:0005634(nucleus);GO:0003723(RNA binding);GO:0006397(mRNA processing);GO:0008380(RNA splicing);GO:0005737(cytoplasm);GO:0016607(nuclear speck);GO:0005515(protein binding);GO:0005681(spliceosomal complex);GO:0006915(apoptotic process);GO:0005654(nucleoplasm);GO:0000375(RNA splicing, via transesterification reactions);GO:0015030(Cajal body);GO:0000398(mRNA splicing, via spliceosome);GO:0000398(mRNA splicing, via spliceosome)","03040(Spliceosome);03040(Spliceosome)","K12839","NA","survival motor neuron domain containing 1 [Source:HGNC Symbol;Acc:HGNC:16900]",{"v":1.69350108233339,"d":"1.69"},{"v":4.15384765479048,"d":"4.15"},{"v":0.407694557690467,"d":"0.41"},{"v":-1.29443939645035,"d":"-1.29"},{"v":0.0582328636834969,"d":"0.06"},{"v":0.706183428476002,"d":"0.71"},"down","no"]
["MSTRG.7416","PPP4R1","ENST00000400555;ENST00000582594;ENST00000400556;MSTRG.7416.3;ENST00000583903;ENST00000580283;ENST00000578557;ENST00000285124;MSTRG.7416.12;ENST00000578329;ENST00000578178;ENST00000583988;ENST00000580745;ENST00000581835;ENST00000583092;ENST00000582240;ENST00000583438;ENST00000580182;ENST00000581250;ENST00000579638;ENST00000577393;MSTRG.7416.11;ENST00000578010;ENST00000580583;ENST00000577779;ENST00000578875;ENST00000584074","GO:0007165(signal transduction);GO:0004721(phosphoprotein phosphatase activity);GO:0005515(protein binding);GO:0050790(regulation of catalytic activity);GO:0019888(protein phosphatase regulator activity);GO:0006470(protein dephosphorylation);GO:0030289(protein phosphatase 4 complex);GO:0006468(protein phosphorylation);GO:0006468(protein phosphorylation)","NA","NA","NA","protein phosphatase 4 regulatory subunit 1 [Source:HGNC Symbol;Acc:HGNC:9320]",{"v":3.69613561325967,"d":"3.70"},{"v":9.00933233100061,"d":"9.01"},{"v":0.410256329488643,"d":"0.41"},{"v":-1.28540250288772,"d":"-1.29"},{"v":0.0584836777239274,"d":"0.06"},{"v":0.70682554188895,"d":"0.71"},"down","no"]
["ENSG00000119866","BCL11A","ENST00000335712;ENST00000359629;ENST00000489516;ENST00000492272;ENST00000489183;ENST00000477659;ENST00000356842;ENST00000358510;ENST00000631857","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0005654(nucleoplasm);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:0001078(transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0007165(signal transduction);GO:0016925(protein sumoylation);GO:0022008(neurogenesis);GO:0019901(protein kinase binding);GO:0010628(positive regulation of gene expression);GO:1903860(negative regulation of dendrite extension);GO:1904800(negative regulation of neuron remodeling);GO:1905232(cellular response to L-glutamate);GO:2000171(negative regulation of dendrite development);GO:2000173(negative regulation of branching morphogenesis of a nerve);GO:0014069(postsynaptic density);GO:0014069(postsynaptic density)","NA","NA","NA","B-cell CLL/lymphoma 11A [Source:HGNC Symbol;Acc:HGNC:13221]",{"v":0.405617567164179,"d":"0.41"},{"v":1.00215816847761,"d":"1.00"},{"v":0.404744061289604,"d":"0.40"},{"v":-1.30491818251491,"d":"-1.30"},{"v":0.0585207216461264,"d":"0.06"},{"v":0.70682554188895,"d":"0.71"},"down","no"]
["MSTRG.13885","NFE4","ENST00000420058;ENST00000638942","NA","NA","NA","NA","nuclear factor, erythroid 4 [Source:HGNC Symbol;Acc:HGNC:29902]",{"v":1.53587994038929,"d":"1.54"},{"v":3.7994296593674,"d":"3.80"},{"v":0.404239603858073,"d":"0.40"},{"v":-1.30671742361332,"d":"-1.31"},{"v":0.0585380141917087,"d":"0.06"},{"v":0.70682554188895,"d":"0.71"},"down","no"]
["ENSG00000120833","SOCS2","ENST00000536696;ENST00000340600;ENST00000549122;ENST00000548537;ENST00000551556;ENST00000549206;ENST00000549510","GO:0005737(cytoplasm);GO:0016567(protein ubiquitination);GO:0035556(intracellular signal transduction);GO:0009967(positive regulation of signal transduction);GO:0005515(protein binding);GO:0001558(regulation of cell growth);GO:0005159(insulin-like growth factor receptor binding);GO:0008269(JAK pathway signal transduction adaptor activity);GO:0046426(negative regulation of JAK-STAT cascade);GO:0005829(cytosol);GO:0040008(regulation of growth);GO:0043687(post-translational protein modification);GO:0004860(protein kinase inhibitor activity);GO:0006469(negative regulation of protein kinase activity);GO:0019221(cytokine-mediated signaling pathway);GO:0043066(negative regulation of apoptotic process);GO:0005070(SH3/SH2 adaptor activity);GO:0005131(growth hormone receptor binding);GO:0007259(JAK-STAT cascade);GO:0009966(regulation of signal transduction);GO:0009968(negative regulation of signal transduction);GO:0032355(response to estradiol);GO:0032870(cellular response to hormone stimulus);GO:0046627(negative regulation of insulin receptor signaling pathway);GO:0060396(growth hormone receptor signaling pathway);GO:0007595(lactation);GO:0040014(regulation of multicellular organism growth);GO:0040015(negative regulation of multicellular organism growth);GO:0045666(positive regulation of neuron differentiation);GO:0060749(mammary gland alveolus development);GO:0060749(mammary gland alveolus development)","04630(Jak-STAT signaling pathway);04910(Insulin signaling pathway);04917(Prolactin signaling pathway);04930(Type II diabetes mellitus);04930(Type II diabetes mellitus)","K04695","NA","suppressor of cytokine signaling 2 [Source:HGNC Symbol;Acc:HGNC:19382]",{"v":0.531746781877214,"d":"0.53"},{"v":0.217548224616293,"d":"0.22"},{"v":2.44427084070715,"d":"2.44"},{"v":1.28940415377203,"d":"1.29"},{"v":0.0585413692383544,"d":"0.06"},{"v":0.70682554188895,"d":"0.71"},"up","no"]
["MSTRG.7567","MBP;AC093330.2","ENST00000397860;ENST00000581878;ENST00000397865;ENST00000493247;ENST00000459948;ENST00000397868;ENST00000397866;ENST00000355994;ENST00000359645;ENST00000527975;ENST00000624814;ENST00000467108;ENST00000447114;ENST00000498683;ENST00000580473;ENST00000533278;ENST00000583798;ENST00000497479;ENST00000484548;ENST00000382582;ENST00000490319;ENST00000397863;ENST00000487778;ENST00000577755;ENST00000482445;ENST00000585201;ENST00000580402;ENST00000495162;ENST00000490754;ENST00000483025;ENST00000528160;ENST00000526111","GO:0005634(nucleus);GO:0016020(membrane);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0019911(structural constituent of myelin sheath);GO:0021762(substantia nigra development);GO:0006955(immune response);GO:0007417(central nervous system development);GO:0043234(protein complex);GO:0007268(chemical synaptic transmission);GO:0043025(neuronal cell body);GO:0043209(myelin sheath);GO:0005516(calmodulin binding);GO:0000165(MAPK cascade);GO:0008366(axon ensheathment);GO:0034115(negative regulation of heterotypic cell-cell adhesion);GO:0035633(maintenance of permeability of blood-brain barrier);GO:0042552(myelination);GO:1904209(positive regulation of chemokine (C-C motif) ligand 2 secretion);GO:1904685(positive regulation of metalloendopeptidase activity);GO:2000778(positive regulation of interleukin-6 secretion);GO:0005622(intracellular);GO:0033269(internode region of axon);GO:0043218(compact myelin);GO:0071944(cell periphery);GO:0002020(protease binding);GO:0007605(sensory perception of sound);GO:0009636(response to toxic substance);GO:0061024(membrane organization);GO:0042995(cell projection);GO:0042995(cell projection)","NA","NA","NA","myelin basic protein [Source:HGNC Symbol;Acc:HGNC:6925]",{"v":5.56362545686169,"d":"5.56"},{"v":2.36966221250112,"d":"2.37"},{"v":2.34785592119875,"d":"2.35"},{"v":1.23134387857158,"d":"1.23"},{"v":0.0586021631774103,"d":"0.06"},{"v":0.70682554188895,"d":"0.71"},"up","no"]
["ENSG00000136541","ERMN","ENST00000410096;ENST00000411762;ENST00000397283;ENST00000409395","GO:0005737(cytoplasm);GO:0003779(actin binding);GO:0005856(cytoskeleton);GO:0070062(extracellular exosome);GO:0005938(cell cortex);GO:0008360(regulation of cell shape);GO:0007015(actin filament organization);GO:0033270(paranode region of axon);GO:0031344(regulation of cell projection organization);GO:0033269(internode region of axon);GO:0051015(actin filament binding);GO:0001763(morphogenesis of a branching structure);GO:0030175(filopodium);GO:0043025(neuronal cell body);GO:0043209(myelin sheath);GO:0043209(myelin sheath)","NA","NA","NA","ermin [Source:HGNC Symbol;Acc:HGNC:29208]",{"v":0.387756997268382,"d":"0.39"},{"v":0.154952641019804,"d":"0.15"},{"v":2.50242264163038,"d":"2.50"},{"v":1.32332547115468,"d":"1.32"},{"v":0.0586379933854062,"d":"0.06"},{"v":0.70682554188895,"d":"0.71"},"up","no"]
["ENSG00000101194","SLC17A9","ENST00000370351;ENST00000459704;ENST00000483113;ENST00000488738;ENST00000411611;ENST00000370349","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005215(transporter activity);GO:0055085(transmembrane transport);GO:0006887(exocytosis);GO:1903146(regulation of mitophagy);GO:1903955(positive regulation of protein targeting to mitochondrion);GO:0022857(transmembrane transporter activity);GO:0006820(anion transport);GO:0006820(anion transport)","NA","NA","NA","solute carrier family 17 member 9 [Source:HGNC Symbol;Acc:HGNC:16192]",{"v":0.814073320594095,"d":"0.81"},{"v":0.341487789893135,"d":"0.34"},{"v":2.38390169337782,"d":"2.38"},{"v":1.25332474360185,"d":"1.25"},{"v":0.0588111643390341,"d":"0.06"},{"v":0.708204040970649,"d":"0.71"},"up","no"]
["ENSG00000184515","BEX5","ENST00000333643;ENST00000484837","GO:0005737(cytoplasm);GO:0005515(protein binding);GO:0070062(extracellular exosome);GO:0070062(extracellular exosome)","NA","NA","NA","brain expressed X-linked 5 [Source:HGNC Symbol;Acc:HGNC:27990]",{"v":2.21952368485419,"d":"2.22"},{"v":0.912191376293509,"d":"0.91"},{"v":2.43317766702941,"d":"2.43"},{"v":1.28284166757762,"d":"1.28"},{"v":0.0590449457405556,"d":"0.06"},{"v":0.709570123193923,"d":"0.71"},"up","no"]
["MSTRG.4856","IGHV4-59","ENST00000390629","GO:0016020(membrane);GO:0005886(plasma membrane);GO:0005576(extracellular region);GO:0006508(proteolysis);GO:0006955(immune response);GO:0002376(immune system process);GO:0003823(antigen binding);GO:0002250(adaptive immune response);GO:0004252(serine-type endopeptidase activity);GO:0006898(receptor-mediated endocytosis);GO:0006956(complement activation);GO:0006958(complement activation, classical pathway);GO:0030449(regulation of complement activation);GO:0038095(Fc-epsilon receptor signaling pathway);GO:0038096(Fc-gamma receptor signaling pathway involved in phagocytosis);GO:0050776(regulation of immune response);GO:0050900(leukocyte migration);GO:0070062(extracellular exosome)","NA","NA","NA","immunoglobulin heavy variable 4-59 [Source:HGNC Symbol;Acc:HGNC:5654]",{"v":21.890461,"d":"21.89"},{"v":9.268864,"d":"9.27"},{"v":2.36171994755776,"d":"2.36"},{"v":1.23983790028816,"d":"1.24"},{"v":0.0590661973033193,"d":"0.06"},{"v":0.709570123193923,"d":"0.71"},"up","no"]
["ENSG00000166979","EVA1C","ENST00000464037;ENST00000412833;ENST00000457807;ENST00000437338;ENST00000435323;ENST00000300255;ENST00000469079;ENST00000459833;ENST00000382699","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0030246(carbohydrate binding);GO:0005576(extracellular region);GO:0008201(heparin binding);GO:0008150(biological_process);GO:0008150(biological_process)","NA","NA","NA","eva-1 homolog C [Source:HGNC Symbol;Acc:HGNC:13239]",{"v":0.729011844015621,"d":"0.73"},{"v":0.302522879623248,"d":"0.30"},{"v":2.40977424558271,"d":"2.41"},{"v":1.26889799706361,"d":"1.27"},{"v":0.0591499405166096,"d":"0.06"},{"v":0.709570123193923,"d":"0.71"},"up","no"]
["ENSG00000131149","GSE1","ENST00000393243;ENST00000253458;ENST00000637419;ENST00000469381;ENST00000495192;ENST00000562659;ENST00000635906;ENST00000496345;ENST00000411612","GO:0005515(protein binding);GO:0005515(protein binding)","NA","NA","NA","Gse1 coiled-coil protein [Source:HGNC Symbol;Acc:HGNC:28979]",{"v":2.97500343452603,"d":"2.98"},{"v":1.26693878568761,"d":"1.27"},{"v":2.34818246006368,"d":"2.35"},{"v":1.23154451407053,"d":"1.23"},{"v":0.0591620399290405,"d":"0.06"},{"v":0.709570123193923,"d":"0.71"},"up","no"]
["MSTRG.6230","CDT1","ENST00000562747;ENST00000301019","GO:0005634(nucleus);GO:0003677(DNA binding);GO:0051301(cell division);GO:0005694(chromosome);GO:0005515(protein binding);GO:0007049(cell cycle);GO:0016604(nuclear body);GO:0006260(DNA replication);GO:0005737(cytoplasm);GO:0007059(chromosome segregation);GO:0000775(chromosome, centromeric region);GO:0000776(kinetochore);GO:0000777(condensed chromosome kinetochore);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0000082(G1/S transition of mitotic cell cycle);GO:0000278(mitotic cell cycle);GO:0051315(attachment of mitotic spindle microtubules to kinetochore);GO:0051383(kinetochore organization);GO:1905342(positive regulation of protein localization to kinetochore);GO:0030174(regulation of DNA-dependent DNA replication initiation);GO:0000083(regulation of transcription involved in G1/S transition of mitotic cell cycle);GO:0003682(chromatin binding);GO:0035563(positive regulation of chromatin binding);GO:0071163(DNA replication preinitiation complex assembly);GO:0072708(response to sorbitol);GO:0031334(positive regulation of protein complex assembly);GO:1902595(regulation of DNA replication origin binding);GO:0000076(DNA replication checkpoint);GO:0033044(regulation of chromosome organization);GO:0033262(regulation of nuclear cell cycle DNA replication);GO:1902426(deactivation of mitotic spindle assembly checkpoint);GO:1905341(negative regulation of protein localization to kinetochore);GO:2000105(positive regulation of DNA-dependent DNA replication);GO:2001178(positive regulation of mediator complex assembly);GO:2001178(positive regulation of mediator complex assembly)","NA","NA","NA","chromatin licensing and DNA replication factor 1 [Source:HGNC Symbol;Acc:HGNC:24576]",{"v":0.517308345323741,"d":"0.52"},{"v":0.204367679856115,"d":"0.20"},{"v":2.53126299465724,"d":"2.53"},{"v":1.33985740921724,"d":"1.34"},{"v":0.0593780596629742,"d":"0.06"},{"v":0.709570123193923,"d":"0.71"},"up","no"]
["ENSG00000181830","SLC35C1","ENST00000314134;ENST00000526817;ENST00000442528","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005794(Golgi apparatus);GO:0000139(Golgi membrane);GO:0008643(carbohydrate transport);GO:0005457(GDP-fucose transmembrane transporter activity);GO:0015783(GDP-fucose transport);GO:0030259(lipid glycosylation);GO:0045746(negative regulation of Notch signaling pathway);GO:0045746(negative regulation of Notch signaling pathway)","NA","NA","NA","solute carrier family 35 member C1 [Source:HGNC Symbol;Acc:HGNC:20197]",{"v":0.668883039955605,"d":"0.67"},{"v":1.64562428279689,"d":"1.65"},{"v":0.406461576283243,"d":"0.41"},{"v":-1.29880911731196,"d":"-1.30"},{"v":0.0593836954659482,"d":"0.06"},{"v":0.709570123193923,"d":"0.71"},"down","no"]
["ENSG00000113456","RAD1","ENST00000382038;ENST00000513914;ENST00000512192;ENST00000511456;ENST00000341754;ENST00000506311;ENST00000628399;ENST00000325577","GO:0005634(nucleus);GO:0043231(intracellular membrane-bounded organelle);GO:0005654(nucleoplasm);GO:0016787(hydrolase activity);GO:0005694(chromosome);GO:0000077(DNA damage checkpoint);GO:0090305(nucleic acid phosphodiester bond hydrolysis);GO:0005515(protein binding);GO:0006281(DNA repair);GO:0006974(cellular response to DNA damage stimulus);GO:0004527(exonuclease activity);GO:0004518(nuclease activity);GO:0021762(substantia nigra development);GO:1901796(regulation of signal transduction by p53 class mediator);GO:0006260(DNA replication);GO:0003684(damaged DNA binding);GO:0071479(cellular response to ionizing radiation);GO:0008408(3'-5' exonuclease activity);GO:0008853(exodeoxyribonuclease III activity);GO:0051598(meiotic recombination checkpoint);GO:0030896(checkpoint clamp complex);GO:0030896(checkpoint clamp complex)","04218(Cellular senescence);04218(Cellular senescence)","K02830","EC:3.1.11.2","RAD1 checkpoint DNA exonuclease [Source:HGNC Symbol;Acc:HGNC:9806]",{"v":0.298666580993201,"d":"0.30"},{"v":0.754101179278747,"d":"0.75"},{"v":0.396056377048578,"d":"0.40"},{"v":-1.33622228806914,"d":"-1.34"},{"v":0.0594206054980464,"d":"0.06"},{"v":0.709570123193923,"d":"0.71"},"down","no"]
["MSTRG.8217","BCL3","ENST00000164227;ENST00000473473;ENST00000403534;ENST00000464319;ENST00000444487;ENST00000477832;ENST00000487394;ENST00000474300;ENST00000473468","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0043231(intracellular membrane-bounded organelle);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0006974(cellular response to DNA damage stimulus);GO:0048471(perinuclear region of cytoplasm);GO:0030496(midbody);GO:0045893(positive regulation of transcription, DNA-templated);GO:0045727(positive regulation of translation);GO:0009615(response to virus);GO:0043234(protein complex);GO:0042981(regulation of apoptotic process);GO:0043066(negative regulation of apoptotic process);GO:0008134(transcription factor binding);GO:0030674(protein binding, bridging);GO:0045892(negative regulation of transcription, DNA-templated);GO:0007249(I-kappaB kinase/NF-kappaB signaling);GO:0030330(DNA damage response, signal transduction by p53 class mediator);GO:0046426(negative regulation of JAK-STAT cascade);GO:0000060(protein import into nucleus, translocation);GO:0051101(regulation of DNA binding);GO:0042771(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator);GO:0045415(negative regulation of interleukin-8 biosynthetic process);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0002268(follicular dendritic cell differentiation);GO:0002315(marginal zone B cell differentiation);GO:0002455(humoral immune response mediated by circulating immunoglobulin);GO:0002467(germinal center formation);GO:0010225(response to UV-C);GO:0019730(antimicrobial humoral response);GO:0030198(extracellular matrix organization);GO:0032729(positive regulation of interferon-gamma production);GO:0042088(T-helper 1 type immune response);GO:0042345(regulation of NF-kappaB import into nucleus);GO:0042536(negative regulation of tumor necrosis factor biosynthetic process);GO:0042742(defense response to bacterium);GO:0042832(defense response to protozoan);GO:0045064(T-helper 2 cell differentiation);GO:0045082(positive regulation of interleukin-10 biosynthetic process);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0048536(spleen development);GO:0051457(maintenance of protein location in nucleus);GO:0032996(Bcl3-Bcl10 complex);GO:0033257(Bcl3/NF-kappaB2 complex);GO:0033257(Bcl3/NF-kappaB2 complex)","04668(TNF signaling pathway);04668(TNF signaling pathway)","K09258","NA","B-cell CLL/lymphoma 3 [Source:HGNC Symbol;Acc:HGNC:998]",{"v":4.93718521344849,"d":"4.94"},{"v":12.0200981971006,"d":"12.02"},{"v":0.410744166352934,"d":"0.41"},{"v":-1.28368800962914,"d":"-1.28"},{"v":0.0594505396821028,"d":"0.06"},{"v":0.709570123193923,"d":"0.71"},"down","no"]
["MSTRG.6906","PLCD3","ENST00000539433;ENST00000590644;ENST00000544446;ENST00000542173;ENST00000546350;ENST00000618022;ENST00000538093;ENST00000619929","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0046872(metal ion binding);GO:0016787(hydrolase activity);GO:0035556(intracellular signal transduction);GO:0007165(signal transduction);GO:0006629(lipid metabolic process);GO:0016042(lipid catabolic process);GO:0004871(signal transducer activity);GO:0001525(angiogenesis);GO:0008081(phosphoric diester hydrolase activity);GO:0005886(plasma membrane);GO:0004435(phosphatidylinositol phospholipase C activity);GO:0042127(regulation of cell proliferation);GO:0032154(cleavage furrow);GO:0043647(inositol phosphate metabolic process);GO:0060716(labyrinthine layer blood vessel development);GO:0005829(cytosol);GO:0005622(intracellular);GO:0005622(intracellular)","00562(Inositol phosphate metabolism);04020(Calcium signaling pathway);04070(Phosphatidylinositol signaling system);04919(Thyroid hormone signaling pathway);04933(AGE-RAGE signaling pathway in diabetic complications);04933(AGE-RAGE signaling pathway in diabetic complications)","K05857","EC:3.1.4.11","phospholipase C delta 3 [Source:HGNC Symbol;Acc:HGNC:9061]",{"v":0.112743542136499,"d":"0.11"},{"v":0.29055656735905,"d":"0.29"},{"v":0.388026136050741,"d":"0.39"},{"v":-1.36577426443145,"d":"-1.37"},{"v":0.0594651660775428,"d":"0.06"},{"v":0.709570123193923,"d":"0.71"},"down","no"]
["ENSG00000173200","PARP15","ENST00000310366;ENST00000493645;ENST00000464300;ENST00000465304;ENST00000473627;ENST00000483793","GO:0005634(nucleus);GO:0016740(transferase activity);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0016757(transferase activity, transferring glycosyl groups);GO:0070403(NAD+ binding);GO:0003950(NAD+ ADP-ribosyltransferase activity);GO:0005515(protein binding);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0070212(protein poly-ADP-ribosylation);GO:0001191(transcriptional repressor activity, RNA polymerase II transcription factor binding);GO:0001191(transcriptional repressor activity, RNA polymerase II transcription factor binding)","NA","NA","NA","poly(ADP-ribose) polymerase family member 15 [Source:HGNC Symbol;Acc:HGNC:26876]",{"v":2.95495097657527,"d":"2.95"},{"v":1.25830081696023,"d":"1.26"},{"v":2.34836609556828,"d":"2.35"},{"v":1.23165733310297,"d":"1.23"},{"v":0.0595358929898716,"d":"0.06"},{"v":0.709570123193923,"d":"0.71"},"up","no"]
["MSTRG.1254","EDEM3","ENST00000318130;ENST00000474725;ENST00000466606;ENST00000466392","GO:0016020(membrane);GO:0046872(metal ion binding);GO:0016787(hydrolase activity);GO:0005509(calcium ion binding);GO:0005783(endoplasmic reticulum);GO:0008152(metabolic process);GO:0016798(hydrolase activity, acting on glycosyl bonds);GO:0004571(mannosyl-oligosaccharide 1,2-alpha-mannosidase activity);GO:0006486(protein glycosylation);GO:0006516(glycoprotein catabolic process);GO:0043161(proteasome-mediated ubiquitin-dependent protein catabolic process);GO:1904382(mannose trimming involved in glycoprotein ERAD pathway);GO:0005788(endoplasmic reticulum lumen);GO:0006986(response to unfolded protein);GO:0006491(N-glycan processing);GO:0030968(endoplasmic reticulum unfolded protein response);GO:0044322(endoplasmic reticulum quality control compartment);GO:0044322(endoplasmic reticulum quality control compartment)","04141(Protein processing in endoplasmic reticulum);04141(Protein processing in endoplasmic reticulum)","K10086","NA","ER degradation enhancing alpha-mannosidase like protein 3 [Source:HGNC Symbol;Acc:HGNC:16787]",{"v":1.7637224437468,"d":"1.76"},{"v":4.2848853898001,"d":"4.28"},{"v":0.411614846909378,"d":"0.41"},{"v":-1.28063307384055,"d":"-1.28"},{"v":0.0595727781555436,"d":"0.06"},{"v":0.709570123193923,"d":"0.71"},"down","no"]
["MSTRG.9294","SLC40A1","ENST00000261024;ENST00000418714;ENST00000479598;ENST00000455320;MSTRG.9294.6","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0005886(plasma membrane);GO:0006811(ion transport);GO:0005515(protein binding);GO:0005622(intracellular);GO:0016323(basolateral plasma membrane);GO:0005381(iron ion transmembrane transporter activity);GO:0034755(iron ion transmembrane transport);GO:0005737(cytoplasm);GO:0005887(integral component of plasma membrane);GO:0006879(cellular iron ion homeostasis);GO:0055072(iron ion homeostasis);GO:0017046(peptide hormone binding);GO:0060586(multicellular organismal iron ion homeostasis);GO:0015093(ferrous iron transmembrane transporter activity);GO:0004872(receptor activity);GO:0097689(iron channel activity);GO:0002260(lymphocyte homeostasis);GO:0003158(endothelium development);GO:0006826(iron ion transport);GO:0034395(regulation of transcription from RNA polymerase II promoter in response to iron);GO:0043066(negative regulation of apoptotic process);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0048536(spleen development);GO:0060345(spleen trabecula formation);GO:1903988(ferrous iron export across plasma membrane);GO:0008021(synaptic vesicle);GO:0008021(synaptic vesicle)","04216(Ferroptosis);04978(Mineral absorption);04978(Mineral absorption)","K14685","NA","solute carrier family 40 member 1 [Source:HGNC Symbol;Acc:HGNC:10909]",{"v":6.5513570360155,"d":"6.55"},{"v":15.8687775311147,"d":"15.87"},{"v":0.412845729494281,"d":"0.41"},{"v":-1.27632531293277,"d":"-1.28"},{"v":0.0599253757825621,"d":"0.06"},{"v":0.712329373802325,"d":"0.71"},"down","no"]
["MSTRG.11078","C3orf38","ENST00000318887;ENST00000485219;ENST00000464919","GO:0005634(nucleus);GO:0006915(apoptotic process);GO:0003674(molecular_function);GO:0043065(positive regulation of apoptotic process);GO:0043065(positive regulation of apoptotic process)","NA","NA","NA","chromosome 3 open reading frame 38 [Source:HGNC Symbol;Acc:HGNC:28384]",{"v":4.02567637349051,"d":"4.03"},{"v":1.71591270471535,"d":"1.72"},{"v":2.34608460117342,"d":"2.35"},{"v":1.23025503872561,"d":"1.23"},{"v":0.0600659509443914,"d":"0.06"},{"v":0.712329373802325,"d":"0.71"},"up","no"]
["ENSG00000215252","GOLGA8B","ENST00000342314;ENST00000569100;ENST00000567956;ENST00000566258;ENST00000564575;ENST00000438958;ENST00000484716;ENST00000566091;ENST00000562282","GO:0016020(membrane);GO:0005794(Golgi apparatus);GO:0005829(cytosol);GO:0032580(Golgi cisterna membrane);GO:0032580(Golgi cisterna membrane)","NA","NA","NA","golgin A8 family member B [Source:HGNC Symbol;Acc:HGNC:31973]",{"v":2.9142591095176,"d":"2.91"},{"v":1.24205218670143,"d":"1.24"},{"v":2.34632581522772,"d":"2.35"},{"v":1.23040336263139,"d":"1.23"},{"v":0.0601759381839284,"d":"0.06"},{"v":0.712329373802325,"d":"0.71"},"up","no"]
["MSTRG.2756","KCTD21","ENST00000340067;ENST00000528776;ENST00000525447","GO:0051260(protein homooligomerization);GO:0051260(protein homooligomerization)","NA","NA","NA","potassium channel tetramerization domain containing 21 [Source:HGNC Symbol;Acc:HGNC:27452]",{"v":1.20124533861671,"d":"1.20"},{"v":2.92817348559078,"d":"2.93"},{"v":0.410237079369753,"d":"0.41"},{"v":-1.28547019886373,"d":"-1.29"},{"v":0.0602100833707682,"d":"0.06"},{"v":0.712329373802325,"d":"0.71"},"down","no"]
["MSTRG.3909","MTMR6","ENST00000381801;ENST00000482345","GO:0005634(nucleus);GO:0016787(hydrolase activity);GO:0004725(protein tyrosine phosphatase activity);GO:0016311(dephosphorylation);GO:0035335(peptidyl-tyrosine dephosphorylation);GO:0005515(protein binding);GO:0071805(potassium ion transmembrane transport);GO:0046856(phosphatidylinositol dephosphorylation);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0052866(phosphatidylinositol phosphate phosphatase activity);GO:0006661(phosphatidylinositol biosynthetic process);GO:0006470(protein dephosphorylation);GO:0005635(nuclear envelope);GO:0004438(phosphatidylinositol-3-phosphatase activity);GO:0052629(phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity);GO:0004722(protein serine/threonine phosphatase activity);GO:0015269(calcium-activated potassium channel activity);GO:0015269(calcium-activated potassium channel activity)","00562(Inositol phosphate metabolism);04070(Phosphatidylinositol signaling system);04070(Phosphatidylinositol signaling system)","K18083","EC:3.1.3.64;EC:3.1.3.95","myotubularin related protein 6 [Source:HGNC Symbol;Acc:HGNC:7453]",{"v":2.65003459266309,"d":"2.65"},{"v":6.41502568766222,"d":"6.42"},{"v":0.413098048501942,"d":"0.41"},{"v":-1.2754438500485,"d":"-1.28"},{"v":0.0603067879946278,"d":"0.06"},{"v":0.712329373802325,"d":"0.71"},"down","no"]
["MSTRG.13599","TRGV4","ENST00000390345","NA","NA","NA","NA","T-cell receptor gamma variable 4 [Source:HGNC Symbol;Acc:HGNC:12289]",{"v":2.993608,"d":"2.99"},{"v":1.211212,"d":"1.21"},{"v":2.47158053255747,"d":"2.47"},{"v":1.30543391518836,"d":"1.31"},{"v":0.0603116729770203,"d":"0.06"},{"v":0.712329373802325,"d":"0.71"},"up","no"]
["ENSG00000233013","FAM157B","ENST00000446912;ENST00000540522;ENST00000639350;ENST00000642084","NA","NA","NA","NA","family with sequence similarity 157 member B (non-protein coding) [Source:HGNC Symbol;Acc:HGNC:34080]",{"v":0.840110599131693,"d":"0.84"},{"v":2.08803507573565,"d":"2.09"},{"v":0.402345060623902,"d":"0.40"},{"v":-1.3134947732843,"d":"-1.31"},{"v":0.0603310633865637,"d":"0.06"},{"v":0.712329373802325,"d":"0.71"},"down","no"]
["ENSG00000213799","ZNF845","ENST00000595091;ENST00000458035;ENST00000601857","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0005622(intracellular);GO:0005622(intracellular)","NA","NA","NA","zinc finger protein 845 [Source:HGNC Symbol;Acc:HGNC:25112]",{"v":0.636264261500113,"d":"0.64"},{"v":0.261709417856334,"d":"0.26"},{"v":2.43118595697382,"d":"2.43"},{"v":1.28166024669597,"d":"1.28"},{"v":0.0603839501771121,"d":"0.06"},{"v":0.712329373802325,"d":"0.71"},"up","no"]
["ENSG00000134265","NAPG","ENST00000322897;ENST00000582978;ENST00000580746;ENST00000582472;ENST00000580483;ENST00000583367","GO:0006810(transport);GO:0016020(membrane);GO:0006886(intracellular protein transport);GO:0015031(protein transport);GO:0005765(lysosomal membrane);GO:0005739(mitochondrion);GO:0016192(vesicle-mediated transport);GO:0019905(syntaxin binding);GO:0005515(protein binding);GO:0070062(extracellular exosome);GO:0050821(protein stabilization);GO:0031201(SNARE complex);GO:0061025(membrane fusion);GO:0006461(protein complex assembly);GO:0006891(intra-Golgi vesicle-mediated transport);GO:0005483(soluble NSF attachment protein activity);GO:0043209(myelin sheath);GO:0005622(intracellular);GO:0005622(intracellular)","NA","NA","NA","NSF attachment protein gamma [Source:HGNC Symbol;Acc:HGNC:7642]",{"v":0.92388898084497,"d":"0.92"},{"v":2.24892778123881,"d":"2.25"},{"v":0.410813094378713,"d":"0.41"},{"v":-1.28344592760769,"d":"-1.28"},{"v":0.0604435329247945,"d":"0.06"},{"v":0.712329373802325,"d":"0.71"},"down","no"]
["MSTRG.5554","PDPK1","ENST00000342085;ENST00000462923;ENST00000492021;ENST00000570136;ENST00000389224;ENST00000491073;ENST00000464702;ENST00000268673;ENST00000474706;ENST00000471311;ENST00000569721","GO:0032148(activation of protein kinase B activity);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0030054(cell junction);GO:0005925(focal adhesion);GO:0038095(Fc-epsilon receptor signaling pathway);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0002223(stimulatory C-type lectin receptor signaling pathway);GO:0050852(T cell receptor signaling pathway);GO:0018105(peptidyl-serine phosphorylation);GO:0097191(extrinsic apoptotic signaling pathway);GO:0030168(platelet activation);GO:0038111(interleukin-7-mediated signaling pathway);GO:0048015(phosphatidylinositol-mediated signaling);GO:0046777(protein autophosphorylation);GO:0006469(negative regulation of protein kinase activity);GO:0030036(actin cytoskeleton organization);GO:0030512(negative regulation of transforming growth factor beta receptor signaling pathway);GO:0004676(3-phosphoinositide-dependent protein kinase activity);GO:0005158(insulin receptor binding);GO:0016004(phospholipase activator activity);GO:0019901(protein kinase binding);GO:0043274(phospholipase binding);GO:0003323(type B pancreatic cell development);GO:0006972(hyperosmotic response);GO:0007173(epidermal growth factor receptor signaling pathway);GO:0010518(positive regulation of phospholipase activity);GO:0010594(regulation of endothelial cell migration);GO:0010667(negative regulation of cardiac muscle cell apoptotic process);GO:0016477(cell migration);GO:0018107(peptidyl-threonine phosphorylation);GO:0019722(calcium-mediated signaling);GO:0031295(T cell costimulation);GO:0032869(cellular response to insulin stimulus);GO:0034122(negative regulation of toll-like receptor signaling pathway);GO:0035556(intracellular signal transduction);GO:0043122(regulation of I-kappaB kinase/NF-kappaB signaling);GO:0043304(regulation of mast cell degranulation);GO:0043524(negative regulation of neuron apoptotic process);GO:0048041(focal adhesion assembly);GO:0051281(positive regulation of release of sequestered calcium ion into cytosol);GO:0071364(cellular response to epidermal growth factor stimulus);GO:0090004(positive regulation of establishment of protein localization to plasma membrane);GO:1990416(cellular response to brain-derived neurotrophic factor stimulus);GO:0014069(postsynaptic density);GO:0031410(cytoplasmic vesicle);GO:0042995(cell projection);GO:0043204(perikaryon);GO:0043204(perikaryon)","04068(FoxO signaling pathway);04071(Sphingolipid signaling pathway);04151(PI3K-Akt signaling pathway);04152(AMPK signaling pathway);04150(mTOR signaling pathway);04140(Autophagy - animal);04210(Apoptosis);04510(Focal adhesion);04660(T cell receptor signaling pathway);04664(Fc epsilon RI signaling pathway);04910(Insulin signaling pathway);03320(PPAR signaling pathway);04919(Thyroid hormone signaling pathway);04960(Aldosterone-regulated sodium reabsorption);04722(Neurotrophin signaling pathway);05231(Choline metabolism in cancer);05205(Proteoglycans in cancer);05215(Prostate cancer);05213(Endometrial cancer);05223(Non-small cell lung cancer);04931(Insulin resistance);05160(Hepatitis C);05145(Toxoplasmosis);01524(Platinum drug resistance);01524(Platinum drug resistance)","K06276","EC:2.7.11.1","3-phosphoinositide dependent protein kinase 1 [Source:HGNC Symbol;Acc:HGNC:8816]",{"v":1.98296243574959,"d":"1.98"},{"v":4.79977997656965,"d":"4.80"},{"v":0.413136111536261,"d":"0.41"},{"v":-1.27531092562211,"d":"-1.28"},{"v":0.0604460312695264,"d":"0.06"},{"v":0.712329373802325,"d":"0.71"},"down","no"]
["MSTRG.9311","CAVIN2","ENST00000304141","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005829(cytosol);GO:0005515(protein binding);GO:0005901(caveola);GO:0045121(membrane raft);GO:0008289(lipid binding);GO:0001786(phosphatidylserine binding);GO:0005543(phospholipid binding);GO:0005080(protein kinase C binding);GO:0097320(plasma membrane tubulation)","NA","NA","NA","caveolae associated protein 2 [Source:HGNC Symbol;Acc:HGNC:10690]",{"v":23.523624,"d":"23.52"},{"v":56.808029,"d":"56.81"},{"v":0.414089775936426,"d":"0.41"},{"v":-1.27198451253192,"d":"-1.27"},{"v":0.0604551253966099,"d":"0.06"},{"v":0.712329373802325,"d":"0.71"},"down","no"]
["ENSG00000273142","AC073335.2","ENST00000610177","NA","NA","NA","NA",null,{"v":1.094067,"d":"1.09"},{"v":0.455929,"d":"0.46"},{"v":2.39964336552402,"d":"2.40"},{"v":1.26282000874148,"d":"1.26"},{"v":0.0606152724951377,"d":"0.06"},{"v":0.713424062387752,"d":"0.71"},"up","no"]
["MSTRG.4125","UPF3A","ENST00000375299;ENST00000351487;ENST00000474056;ENST00000479712;ENST00000492270;ENST00000475218;ENST00000618700;ENST00000480362;ENST00000493727;ENST00000619079","GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0006810(transport);GO:0051028(mRNA transport);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0043231(intracellular membrane-bounded organelle);GO:0005829(cytosol);GO:0006913(nucleocytoplasmic transport);GO:0005515(protein binding);GO:0045727(positive regulation of translation);GO:0035145(exon-exon junction complex);GO:0000184(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay);GO:0042162(telomeric DNA binding);GO:0005487(nucleocytoplasmic transporter activity);GO:0005622(intracellular);GO:0005622(intracellular)","03013(RNA transport);03015(mRNA surveillance pathway);03015(mRNA surveillance pathway)","K14328","NA","UPF3A, regulator of nonsense mediated mRNA decay [Source:HGNC Symbol;Acc:HGNC:20332]",{"v":4.08085188600139,"d":"4.08"},{"v":1.74305115609841,"d":"1.74"},{"v":2.34121177208352,"d":"2.34"},{"v":1.22725543795971,"d":"1.23"},{"v":0.060725571143711,"d":"0.06"},{"v":0.713424062387752,"d":"0.71"},"up","no"]
["MSTRG.12985","MAPK14","ENST00000229794;ENST00000229795;ENST00000474429;ENST00000490379;ENST00000622903;ENST00000472333;ENST00000491957;ENST00000310795;ENST00000468133;ENST00000496250","GO:0045648(positive regulation of erythrocyte differentiation);GO:0005737(cytoplasm);GO:0005634(nucleus);GO:0016607(nuclear speck);GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0016740(transferase activity);GO:0004707(MAP kinase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0005515(protein binding);GO:0006915(apoptotic process);GO:0005576(extracellular region);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0098586(cellular response to virus);GO:0010628(positive regulation of gene expression);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0043312(neutrophil degranulation);GO:0051525(NFAT protein binding);GO:0000077(DNA damage checkpoint);GO:0000902(cell morphogenesis);GO:0001502(cartilage condensation);GO:0001525(angiogenesis);GO:0001890(placenta development);GO:0002062(chondrocyte differentiation);GO:0002741(positive regulation of cytokine secretion involved in immune response);GO:0006006(glucose metabolic process);GO:0006974(cellular response to DNA damage stimulus);GO:0007178(transmembrane receptor protein serine/threonine kinase signaling pathway);GO:0007519(skeletal muscle tissue development);GO:0010759(positive regulation of macrophage chemotaxis);GO:0010831(positive regulation of myotube differentiation);GO:0014835(myoblast differentiation involved in skeletal muscle regeneration);GO:0018105(peptidyl-serine phosphorylation);GO:0019395(fatty acid oxidation);GO:0030278(regulation of ossification);GO:0030316(osteoclast differentiation);GO:0031663(lipopolysaccharide-mediated signaling pathway);GO:0032495(response to muramyl dipeptide);GO:0032496(response to lipopolysaccharide);GO:0035556(intracellular signal transduction);GO:0035994(response to muscle stretch);GO:0038066(p38MAPK cascade);GO:0042307(positive regulation of protein import into nucleus);GO:0045663(positive regulation of myoblast differentiation);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0046326(positive regulation of glucose import);GO:0051146(striated muscle cell differentiation);GO:0060045(positive regulation of cardiac muscle cell proliferation);GO:0090090(negative regulation of canonical Wnt signaling pathway);GO:0090336(positive regulation of brown fat cell differentiation);GO:1901741(positive regulation of myoblast fusion);GO:1905050(positive regulation of metallopeptidase activity);GO:0000922(spindle pole);GO:0005623(cell);GO:0005739(mitochondrion);GO:0006935(chemotaxis);GO:0007165(signal transduction);GO:2001184(positive regulation of interleukin-12 secretion);GO:0019903(protein phosphatase binding);GO:0034774(secretory granule lumen);GO:1904813(ficolin-1-rich granule lumen);GO:0007166(cell surface receptor signaling pathway);GO:1901796(regulation of signal transduction by p53 class mediator);GO:0006928(movement of cell or subcellular component);GO:0048010(vascular endothelial growth factor receptor signaling pathway);GO:0019899(enzyme binding);GO:0035924(cellular response to vascular endothelial growth factor stimulus);GO:0000187(activation of MAPK activity);GO:0051149(positive regulation of muscle cell differentiation);GO:0071223(cellular response to lipoteichoic acid);GO:2000379(positive regulation of reactive oxygen species metabolic process);GO:0051090(regulation of sequence-specific DNA binding transcription factor activity);GO:0007265(Ras protein signal transduction);GO:0071222(cellular response to lipopolysaccharide);GO:0042770(signal transduction in response to DNA damage);GO:0071479(cellular response to ionizing radiation);GO:0070935(3'-UTR-mediated mRNA stabilization);GO:0031281(positive regulation of cyclase activity);GO:0090400(stress-induced premature senescence);GO:0004708(MAP kinase kinase activity);GO:0048273(mitogen-activated protein kinase p38 binding);GO:1900015(regulation of cytokine production involved in inflammatory response);GO:0000165(MAPK cascade);GO:0005622(intracellular);GO:0005622(intracellular)","04015(Rap1 signaling pathway);04010(MAPK signaling pathway);04370(VEGF signaling pathway);04668(TNF signaling pathway);04068(FoxO signaling pathway);04071(Sphingolipid signaling pathway);04218(Cellular senescence);04550(Signaling pathways regulating pluripotency of stem cells);04611(Platelet activation);04620(Toll-like receptor signaling pathway);04621(NOD-like receptor signaling pathway);04622(RIG-I-like receptor signaling pathway);04660(T cell receptor signaling pathway);04658(Th1 and Th2 cell differentiation);04659(Th17 cell differentiation);04657(IL-17 signaling pathway);04664(Fc epsilon RI signaling pathway);04670(Leukocyte transendothelial migration);04912(GnRH signaling pathway);04914(Progesterone-mediated oocyte maturation);04917(Prolactin signaling pathway);04926(Relaxin signaling pathway);04261(Adrenergic signaling in cardiomyocytes);04728(Dopaminergic synapse);04723(Retrograde endocannabinoid signaling);04722(Neurotrophin signaling pathway);04750(Inflammatory mediator regulation of TRP channels);04380(Osteoclast differentiation);05205(Proteoglycans in cancer);05014(Amyotrophic lateral sclerosis (ALS));05418(Fluid shear stress and atherosclerosis);04933(AGE-RAGE signaling pathway in diabetic complications);05120(Epithelial cell signaling in Helicobacter pylori infection);05132(Salmonella infection);05131(Shigellosis);05133(Pertussis);05152(Tuberculosis);05164(Influenza A);05160(Hepatitis C);05167(Kaposi's sarcoma-associated herpesvirus infection);05169(Epstein-Barr virus infection);05145(Toxoplasmosis);05140(Leishmaniasis);05142(Chagas disease (American trypanosomiasis));01522(Endocrine resistance);01522(Endocrine resistance)","K04441","EC:2.7.11.24","mitogen-activated protein kinase 14 [Source:HGNC Symbol;Acc:HGNC:6876]",{"v":4.3674288164723,"d":"4.37"},{"v":10.5486484034985,"d":"10.55"},{"v":0.414027337855324,"d":"0.41"},{"v":-1.27220206415268,"d":"-1.27"},{"v":0.0608132675049697,"d":"0.06"},{"v":0.713424062387752,"d":"0.71"},"down","no"]
["MSTRG.6547","TNFAIP1","ENST00000226225;ENST00000544907;ENST00000577535;ENST00000582302","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005730(nucleolus);GO:0016567(protein ubiquitination);GO:0051260(protein homooligomerization);GO:0005515(protein binding);GO:0006955(immune response);GO:0006915(apoptotic process);GO:0006260(DNA replication);GO:0005768(endosome);GO:0004842(ubiquitin-protein transferase activity);GO:0043161(proteasome-mediated ubiquitin-dependent protein catabolic process);GO:0016477(cell migration);GO:0009790(embryo development);GO:0017049(GTP-Rho binding);GO:0031463(Cul3-RING ubiquitin ligase complex);GO:0043149(stress fiber assembly);GO:0035024(negative regulation of Rho protein signal transduction);GO:0019904(protein domain specific binding);GO:0045740(positive regulation of DNA replication);GO:0045740(positive regulation of DNA replication)","NA","NA","NA","TNF alpha induced protein 1 [Source:HGNC Symbol;Acc:HGNC:11894]",{"v":1.32762377140653,"d":"1.33"},{"v":3.23564469889432,"d":"3.24"},{"v":0.410311976423185,"d":"0.41"},{"v":-1.2852068298254,"d":"-1.29"},{"v":0.0608271839774401,"d":"0.06"},{"v":0.713424062387752,"d":"0.71"},"down","no"]
["MSTRG.7597","SBNO2","ENST00000361757;ENST00000438103;ENST00000586109;ENST00000590998;ENST00000587024;ENST00000587673;ENST00000587655;ENST00000590176;ENST00000592222;ENST00000590446","GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0030154(cell differentiation);GO:0050727(regulation of inflammatory response);GO:0005575(cellular_component);GO:0071222(cellular response to lipopolysaccharide);GO:0001503(ossification);GO:0045892(negative regulation of transcription, DNA-templated);GO:0071354(cellular response to interleukin-6);GO:0002281(macrophage activation involved in immune response);GO:0030282(bone mineralization);GO:0030316(osteoclast differentiation);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0061430(bone trabecula morphogenesis);GO:0071348(cellular response to interleukin-11);GO:0072674(multinuclear osteoclast differentiation);GO:0072675(osteoclast fusion);GO:1990830(cellular response to leukemia inhibitory factor);GO:1990830(cellular response to leukemia inhibitory factor)","NA","NA","NA","strawberry notch homolog 2 [Source:HGNC Symbol;Acc:HGNC:29158]",{"v":7.96523345668578,"d":"7.97"},{"v":19.2285674289164,"d":"19.23"},{"v":0.414239567566925,"d":"0.41"},{"v":-1.27146273059449,"d":"-1.27"},{"v":0.0608668984616473,"d":"0.06"},{"v":0.713424062387752,"d":"0.71"},"down","no"]
["MSTRG.8215","PLAUR","ENST00000340093;ENST00000339082;ENST00000594364;ENST00000599892;ENST00000593939;ENST00000602141;ENST00000601876;ENST00000221264;ENST00000598875;ENST00000593396;ENST00000593714;ENST00000593447;ENST00000595038;ENST00000599546;ENST00000601723","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005886(plasma membrane);GO:0042995(cell projection);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0030054(cell junction);GO:0019904(protein domain specific binding);GO:0031225(anchored component of membrane);GO:0005925(focal adhesion);GO:0005789(endoplasmic reticulum membrane);GO:0070062(extracellular exosome);GO:0030162(regulation of proteolysis);GO:0004872(receptor activity);GO:0005102(receptor binding);GO:0043312(neutrophil degranulation);GO:0035579(specific granule membrane);GO:0030377(urokinase plasminogen activator receptor activity);GO:0038195(urokinase plasminogen activator signaling pathway);GO:0006935(chemotaxis);GO:0007165(signal transduction);GO:0019899(enzyme binding);GO:0007596(blood coagulation);GO:0005788(endoplasmic reticulum lumen);GO:0019898(extrinsic component of membrane);GO:0006928(movement of cell or subcellular component);GO:0016255(attachment of GPI anchor to protein);GO:0001934(positive regulation of protein phosphorylation);GO:0043066(negative regulation of apoptotic process);GO:0042730(fibrinolysis);GO:0071438(invadopodium membrane);GO:0009986(cell surface);GO:0043388(positive regulation of DNA binding);GO:0045742(positive regulation of epidermal growth factor receptor signaling pathway);GO:0090200(positive regulation of release of cytochrome c from mitochondria);GO:2001243(negative regulation of intrinsic apoptotic signaling pathway);GO:2001268(negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway);GO:0005887(integral component of plasma membrane);GO:0005887(integral component of plasma membrane)","04610(Complement and coagulation cascades);05205(Proteoglycans in cancer);05205(Proteoglycans in cancer)","K03985","NA","plasminogen activator, urokinase receptor [Source:HGNC Symbol;Acc:HGNC:9053]",{"v":3.46839988400269,"d":"3.47"},{"v":8.39210465402737,"d":"8.39"},{"v":0.413293211535226,"d":"0.41"},{"v":-1.27476242767841,"d":"-1.27"},{"v":0.0609953688106152,"d":"0.06"},{"v":0.713424062387752,"d":"0.71"},"down","no"]
["MSTRG.424","CSF3R","ENST00000331941;ENST00000373104;ENST00000361632;ENST00000489551;MSTRG.424.2;ENST00000464365;ENST00000480825;ENST00000373103;ENST00000464465;ENST00000533491;ENST00000466138;MSTRG.424.1;ENST00000373106;ENST00000484762;ENST00000526980;ENST00000469380;ENST00000487540","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0007155(cell adhesion);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0004896(cytokine receptor activity);GO:0019221(cytokine-mediated signaling pathway);GO:0005887(integral component of plasma membrane);GO:0007165(signal transduction);GO:0004872(receptor activity);GO:0006952(defense response);GO:0051916(granulocyte colony-stimulating factor binding);GO:0030593(neutrophil chemotaxis);GO:0045637(regulation of myeloid cell differentiation);GO:0097186(amelogenesis);GO:0097186(amelogenesis)","04630(Jak-STAT signaling pathway);04151(PI3K-Akt signaling pathway);04060(Cytokine-cytokine receptor interaction);04640(Hematopoietic cell lineage);05200(Pathways in cancer);05200(Pathways in cancer)","K05061","NA","colony stimulating factor 3 receptor [Source:HGNC Symbol;Acc:HGNC:2439]",{"v":64.5381810757893,"d":"64.54"},{"v":155.487892284135,"d":"155.49"},{"v":0.415068852807225,"d":"0.42"},{"v":-1.26857742020079,"d":"-1.27"},{"v":0.0610214752401292,"d":"0.06"},{"v":0.713424062387752,"d":"0.71"},"down","no"]
["ENSG00000141013","GAS8","ENST00000564853;ENST00000268699;ENST00000564789;ENST00000620723;ENST00000569558;ENST00000536122;ENST00000564802;ENST00000569399","GO:0005737(cytoplasm);GO:0031514(motile cilium);GO:0005794(Golgi apparatus);GO:0005856(cytoskeleton);GO:0042995(cell projection);GO:0005874(microtubule);GO:0048870(cell motility);GO:0008017(microtubule binding);GO:0017137(Rab GTPase binding);GO:0005929(cilium);GO:0003674(molecular_function);GO:0005930(axoneme);GO:0036064(ciliary basal body);GO:0008285(negative regulation of cell proliferation);GO:0030317(flagellated sperm motility);GO:0034613(cellular protein localization);GO:0060294(cilium movement involved in cell motility);GO:1904526(regulation of microtubule binding);GO:0003351(epithelial cilium movement);GO:0007368(determination of left/right symmetry);GO:0007420(brain development);GO:0035082(axoneme assembly);GO:0015630(microtubule cytoskeleton);GO:0036126(sperm flagellum);GO:0097729(9+2 motile cilium);GO:0097729(9+2 motile cilium)","NA","NA","NA","growth arrest specific 8 [Source:HGNC Symbol;Acc:HGNC:4166]",{"v":0.381547827070347,"d":"0.38"},{"v":0.152706251825467,"d":"0.15"},{"v":2.49857371593686,"d":"2.50"},{"v":1.32110478283174,"d":"1.32"},{"v":0.061081233044492,"d":"0.06"},{"v":0.713424062387752,"d":"0.71"},"up","no"]
["ENSG00000179921","GPBAR1","ENST00000519574;ENST00000521462;ENST00000479077;ENST00000522678","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0004930(G-protein coupled receptor activity);GO:0007186(G-protein coupled receptor signaling pathway);GO:0005886(plasma membrane);GO:0004871(signal transducer activity);GO:0007165(signal transduction);GO:0038181(bile acid receptor activity);GO:0038182(G-protein coupled bile acid receptor activity);GO:0038184(cell surface bile acid receptor signaling pathway);GO:2000810(regulation of bicellular tight junction assembly);GO:2000810(regulation of bicellular tight junction assembly)","NA","NA","NA","G protein-coupled bile acid receptor 1 [Source:HGNC Symbol;Acc:HGNC:19680]",{"v":0.315352332095097,"d":"0.32"},{"v":0.817983002971768,"d":"0.82"},{"v":0.38552430912306,"d":"0.39"},{"v":-1.37510626316319,"d":"-1.38"},{"v":0.061081233044492,"d":"0.06"},{"v":0.713424062387752,"d":"0.71"},"down","no"]
["ENSG00000109133","TMEM33","ENST00000504986;ENST00000506794;ENST00000508448;ENST00000513702;ENST00000264452;ENST00000513558;ENST00000325094;ENST00000510383","GO:0005634(nucleus);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0042470(melanosome);GO:0005515(protein binding);GO:0008150(biological_process);GO:0070062(extracellular exosome);GO:0005643(nuclear pore);GO:0030176(integral component of endoplasmic reticulum membrane);GO:0034976(response to endoplasmic reticulum stress);GO:0005635(nuclear envelope);GO:0017056(structural constituent of nuclear pore);GO:1903896(positive regulation of IRE1-mediated unfolded protein response);GO:1903899(positive regulation of PERK-mediated unfolded protein response);GO:0034613(cellular protein localization);GO:0051292(nuclear pore complex assembly);GO:1903371(regulation of endoplasmic reticulum tubular network organization);GO:1903371(regulation of endoplasmic reticulum tubular network organization)","NA","NA","NA","transmembrane protein 33 [Source:HGNC Symbol;Acc:HGNC:25541]",{"v":1.58439102415049,"d":"1.58"},{"v":3.82606988228155,"d":"3.83"},{"v":0.414104047468597,"d":"0.41"},{"v":-1.27193479115485,"d":"-1.27"},{"v":0.061447241324201,"d":"0.06"},{"v":0.715266404495312,"d":"0.72"},"down","no"]
["MSTRG.3557","GLIPR1","ENST00000266659;ENST00000456650;ENST00000550491;ENST00000536703","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005576(extracellular region);GO:0005886(plasma membrane);GO:0043312(neutrophil degranulation);GO:0035577(azurophil granule membrane);GO:0019216(regulation of lipid metabolic process);GO:0019216(regulation of lipid metabolic process)","NA","NA","NA","GLI pathogenesis related 1 [Source:HGNC Symbol;Acc:HGNC:17001]",{"v":11.0791184925873,"d":"11.08"},{"v":26.6741107667783,"d":"26.67"},{"v":0.415350996681995,"d":"0.42"},{"v":-1.26759707854624,"d":"-1.27"},{"v":0.0614726366868325,"d":"0.06"},{"v":0.715266404495312,"d":"0.72"},"down","no"]
["MSTRG.10432","LGALS2","ENST00000215886;ENST00000416480","GO:0030246(carbohydrate binding);GO:0005515(protein binding);GO:0016936(galactoside binding);GO:0016936(galactoside binding)","NA","NA","NA","galectin 2 [Source:HGNC Symbol;Acc:HGNC:6562]",{"v":6.74043280072464,"d":"6.74"},{"v":16.3478986135266,"d":"16.35"},{"v":0.412311879347445,"d":"0.41"},{"v":-1.27819206677137,"d":"-1.28"},{"v":0.0614765436932885,"d":"0.06"},{"v":0.715266404495312,"d":"0.72"},"down","no"]
["MSTRG.8399","OSCAR","ENST00000359649;ENST00000358375;ENST00000391761;ENST00000391760;ENST00000611261;ENST00000351806;ENST00000284648;ENST00000356532;ENST00000616447","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005886(plasma membrane);GO:0005576(extracellular region);GO:0050776(regulation of immune response);GO:0070062(extracellular exosome);GO:0043312(neutrophil degranulation);GO:0035580(specific granule lumen);GO:1904724(tertiary granule lumen);GO:1904724(tertiary granule lumen)","04380(Osteoclast differentiation);04380(Osteoclast differentiation)","K14377","NA","osteoclast associated, immunoglobulin-like receptor [Source:HGNC Symbol;Acc:HGNC:29960]",{"v":3.19281150623202,"d":"3.19"},{"v":7.77437036720997,"d":"7.77"},{"v":0.410684255499117,"d":"0.41"},{"v":-1.28389845545631,"d":"-1.28"},{"v":0.0614765594297167,"d":"0.06"},{"v":0.715266404495312,"d":"0.72"},"down","no"]
["MSTRG.3270","STK38L","ENST00000389032;ENST00000543992;ENST00000434385;ENST00000407753;ENST00000539863;ENST00000541191;ENST00000540996;ENST00000543246;ENST00000545470;ENST00000546286;ENST00000536093;ENST00000544367;ENST00000544969","GO:0004672(protein kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0005829(cytosol);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0004674(protein serine/threonine kinase activity);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0003779(actin binding);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0000287(magnesium ion binding);GO:0018105(peptidyl-serine phosphorylation);GO:0035556(intracellular signal transduction);GO:0015629(actin cytoskeleton);GO:0051128(regulation of cellular component organization);GO:0051128(regulation of cellular component organization)","NA","NA","NA","serine/threonine kinase 38 like [Source:HGNC Symbol;Acc:HGNC:17848]",{"v":1.67733861479555,"d":"1.68"},{"v":4.05175647724317,"d":"4.05"},{"v":0.413978141138635,"d":"0.41"},{"v":-1.27237350229187,"d":"-1.27"},{"v":0.0616716630604794,"d":"0.06"},{"v":0.716271723164288,"d":"0.72"},"down","no"]
["MSTRG.8508","HPCAL1","ENST00000307845;ENST00000419810;MSTRG.8508.3;ENST00000622018;ENST00000423674;ENST00000422133","GO:0016020(membrane);GO:0046872(metal ion binding);GO:0005509(calcium ion binding);GO:0005515(protein binding);GO:0070062(extracellular exosome);GO:0070062(extracellular exosome)","NA","NA","NA","hippocalcin like 1 [Source:HGNC Symbol;Acc:HGNC:5145]",{"v":3.08386142103575,"d":"3.08"},{"v":7.43286801619368,"d":"7.43"},{"v":0.414895221375796,"d":"0.41"},{"v":-1.26918105406041,"d":"-1.27"},{"v":0.0616839989941168,"d":"0.06"},{"v":0.716271723164288,"d":"0.72"},"down","no"]
["ENSG00000163803","PLB1","ENST00000422425;ENST00000411743;ENST00000444257;ENST00000473272;ENST00000485642;ENST00000436544;ENST00000436775","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016787(hydrolase activity);GO:0006629(lipid metabolic process);GO:0016042(lipid catabolic process);GO:0005886(plasma membrane);GO:0016788(hydrolase activity, acting on ester bonds);GO:0042572(retinol metabolic process);GO:0004623(phospholipase A2 activity);GO:0016298(lipase activity);GO:0016324(apical plasma membrane);GO:0001523(retinoid metabolic process);GO:0036151(phosphatidylcholine acyl-chain remodeling);GO:0004622(lysophospholipase activity);GO:0050253(retinyl-palmitate esterase activity);GO:2000344(positive regulation of acrosome reaction);GO:2000344(positive regulation of acrosome reaction)","00564(Glycerophospholipid metabolism);00565(Ether lipid metabolism);00590(Arachidonic acid metabolism);00591(Linoleic acid metabolism);00592(alpha-Linolenic acid metabolism);04977(Vitamin digestion and absorption);04977(Vitamin digestion and absorption)","K14621","EC:3.1.1.4;EC:3.1.1.5","phospholipase B1 [Source:HGNC Symbol;Acc:HGNC:30041]",{"v":0.80690676244234,"d":"0.81"},{"v":1.95221947353727,"d":"1.95"},{"v":0.413327893395248,"d":"0.41"},{"v":-1.27464136774613,"d":"-1.27"},{"v":0.0617414091217847,"d":"0.06"},{"v":0.716271723164288,"d":"0.72"},"down","no"]
["MSTRG.14407","LY96","ENST00000284818;MSTRG.14407.2;ENST00000518893","GO:0005515(protein binding);GO:0005576(extracellular region);GO:0005615(extracellular space);GO:0002376(immune system process);GO:0045087(innate immune response);GO:0006954(inflammatory response);GO:0005886(plasma membrane);GO:0010008(endosome membrane);GO:0001875(lipopolysaccharide receptor activity);GO:0002224(toll-like receptor signaling pathway);GO:0002755(MyD88-dependent toll-like receptor signaling pathway);GO:0002756(MyD88-independent toll-like receptor signaling pathway);GO:0007249(I-kappaB kinase/NF-kappaB signaling);GO:0032496(response to lipopolysaccharide);GO:0032497(detection of lipopolysaccharide);GO:0034128(negative regulation of MyD88-independent toll-like receptor signaling pathway);GO:0034142(toll-like receptor 4 signaling pathway);GO:0035666(TRIF-dependent toll-like receptor signaling pathway);GO:0070266(necroptotic process);GO:0097190(apoptotic signaling pathway);GO:0031226(intrinsic component of plasma membrane);GO:0046696(lipopolysaccharide receptor complex);GO:0007166(cell surface receptor signaling pathway);GO:0015026(coreceptor activity);GO:0006968(cellular defense response);GO:0032760(positive regulation of tumor necrosis factor production);GO:0031663(lipopolysaccharide-mediated signaling pathway);GO:0031666(positive regulation of lipopolysaccharide-mediated signaling pathway);GO:0071222(cellular response to lipopolysaccharide);GO:0071222(cellular response to lipopolysaccharide)","04064(NF-kappa B signaling pathway);04620(Toll-like receptor signaling pathway);05130(Pathogenic Escherichia coli infection);05133(Pertussis);05145(Toxoplasmosis);05145(Toxoplasmosis)","K05400","NA","lymphocyte antigen 96 [Source:HGNC Symbol;Acc:HGNC:17156]",{"v":4.5324169860583,"d":"4.53"},{"v":11.0644151837769,"d":"11.06"},{"v":0.409639091698576,"d":"0.41"},{"v":-1.28757469715541,"d":"-1.29"},{"v":0.0618649974430999,"d":"0.06"},{"v":0.717014724937256,"d":"0.72"},"down","no"]
["MSTRG.15102","FAM69B","ENST00000371692;ENST00000371691","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005515(protein binding);GO:0005515(protein binding)","NA","NA","NA","family with sequence similarity 69 member B [Source:HGNC Symbol;Acc:HGNC:28290]",{"v":0.314089899408284,"d":"0.31"},{"v":0.796097077662722,"d":"0.80"},{"v":0.39453718424696,"d":"0.39"},{"v":-1.34176681746074,"d":"-1.34"},{"v":0.062100040959019,"d":"0.06"},{"v":0.717837758883637,"d":"0.72"},"down","no"]
["ENSG00000173402","DAG1","ENST00000308775;ENST00000479935;ENST00000461987;ENST00000428779;ENST00000421560;ENST00000435508;ENST00000538711;ENST00000545947","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005509(calcium ion binding);GO:0003779(actin binding);GO:0005886(plasma membrane);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0005615(extracellular space);GO:0030054(cell junction);GO:0045202(synapse);GO:0045211(postsynaptic membrane);GO:0005654(nucleoplasm);GO:0005925(focal adhesion);GO:0005604(basement membrane);GO:0007016(cytoskeletal anchoring at plasma membrane);GO:0046718(viral entry into host cell);GO:0005829(cytosol);GO:0030027(lamellipodium);GO:0030175(filopodium);GO:0070062(extracellular exosome);GO:0042169(SH2 domain binding);GO:0042383(sarcolemma);GO:0016032(viral process);GO:0010717(regulation of epithelial to mesenchymal transition);GO:0016010(dystrophin-associated glycoprotein complex);GO:0005788(endoplasmic reticulum lumen);GO:0006607(NLS-bearing protein import into nucleus);GO:0015631(tubulin binding);GO:0030198(extracellular matrix organization);GO:0005796(Golgi lumen);GO:0006509(membrane protein ectodomain proteolysis);GO:0051898(negative regulation of protein kinase B signaling);GO:0008307(structural constituent of muscle);GO:0017166(vinculin binding);GO:0001618(virus receptor activity);GO:0030336(negative regulation of cell migration);GO:0006493(protein O-linked glycosylation);GO:0070938(contractile ring);GO:0010470(regulation of gastrulation);GO:0034453(microtubule anchoring);GO:1904261(positive regulation of basement membrane assembly involved in embryonic body morphogenesis);GO:0043409(negative regulation of MAPK cascade);GO:0043237(laminin-1 binding);GO:0019048(modulation by virus of host morphology or physiology);GO:0016476(regulation of embryonic cell shape);GO:0051393(alpha-actinin binding);GO:0002162(dystroglycan binding);GO:0043236(laminin binding);GO:0001954(positive regulation of cell-matrix adhesion);GO:0002011(morphogenesis of an epithelial sheet);GO:0007568(aging);GO:0014037(Schwann cell differentiation);GO:0014044(Schwann cell development);GO:0014894(response to denervation involved in regulation of muscle adaptation);GO:0016340(calcium-dependent cell-matrix adhesion);GO:0021675(nerve development);GO:0021682(nerve maturation);GO:0022011(myelination in peripheral nervous system);GO:0031103(axon regeneration);GO:0031643(positive regulation of myelination);GO:0043403(skeletal muscle tissue regeneration);GO:0043434(response to peptide hormone);GO:0045860(positive regulation of protein kinase activity);GO:0048714(positive regulation of oligodendrocyte differentiation);GO:0060055(angiogenesis involved in wound healing);GO:0060441(epithelial tube branching involved in lung morphogenesis);GO:0060445(branching involved in salivary gland morphogenesis);GO:0071260(cellular response to mechanical stimulus);GO:0071397(cellular response to cholesterol);GO:0071679(commissural neuron axon guidance);GO:0071711(basement membrane organization);GO:0005911(cell-cell junction);GO:0005913(cell-cell adherens junction);GO:0009897(external side of plasma membrane);GO:0016011(dystroglycan complex);GO:0016323(basolateral plasma membrane);GO:0033268(node of Ranvier);GO:0034399(nuclear periphery);GO:0043034(costamere);GO:0044853(plasma membrane raft);GO:0045121(membrane raft);GO:0045121(membrane raft)","04512(ECM-receptor interaction);05410(Hypertrophic cardiomyopathy (HCM));05412(Arrhythmogenic right ventricular cardiomyopathy (ARVC));05414(Dilated cardiomyopathy (DCM));05416(Viral myocarditis);05416(Viral myocarditis)","K06265","NA","dystroglycan 1 [Source:HGNC Symbol;Acc:HGNC:2666]",{"v":2.38856990943233,"d":"2.39"},{"v":1.02500862097357,"d":"1.03"},{"v":2.33029250735826,"d":"2.33"},{"v":1.22051105892617,"d":"1.22"},{"v":0.0621056459774059,"d":"0.06"},{"v":0.717837758883637,"d":"0.72"},"up","no"]
["MSTRG.2113","TSSC4","ENST00000380996;ENST00000380992;ENST00000485682;ENST00000333256;ENST00000451491;ENST00000440813;ENST00000496468;ENST00000435795","GO:0005515(protein binding);GO:0005515(protein binding)","NA","NA","NA","tumor suppressing subtransferable candidate 4 [Source:HGNC Symbol;Acc:HGNC:12386]",{"v":0.953214755547198,"d":"0.95"},{"v":2.32636744151937,"d":"2.33"},{"v":0.409743851523578,"d":"0.41"},{"v":-1.28720579398971,"d":"-1.29"},{"v":0.0621148434443406,"d":"0.06"},{"v":0.717837758883637,"d":"0.72"},"down","no"]
["MSTRG.11769","SLC9B2;BDH2","ENST00000394785;ENST00000296424;ENST00000464039;ENST00000492366;ENST00000475058;ENST00000513518;ENST00000503103;ENST00000505838","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0055085(transmembrane transport);GO:0005739(mitochondrion);GO:0006811(ion transport);GO:0005886(plasma membrane);GO:0042995(cell projection);GO:0015297(antiporter activity);GO:0015299(solute:proton antiporter activity);GO:0006812(cation transport);GO:0006814(sodium ion transport);GO:0035725(sodium ion transmembrane transport);GO:1902600(hydrogen ion transmembrane transport);GO:0030054(cell junction);GO:0045202(synapse);GO:0031410(cytoplasmic vesicle);GO:0015992(proton transport);GO:0031966(mitochondrial membrane);GO:0005768(endosome);GO:0034220(ion transmembrane transport);GO:0016323(basolateral plasma membrane);GO:0042802(identical protein binding);GO:0010008(endosome membrane);GO:0016324(apical plasma membrane);GO:0030672(synaptic vesicle membrane);GO:0005743(mitochondrial inner membrane);GO:0030317(flagellated sperm motility);GO:0015385(sodium:proton antiporter activity);GO:0097228(sperm principal piece);GO:0005451(monovalent cation:proton antiporter activity);GO:0010348(lithium:proton antiporter activity);GO:0061178(regulation of insulin secretion involved in cellular response to glucose stimulus);GO:0072583(clathrin-dependent endocytosis);GO:2001206(positive regulation of osteoclast development);GO:0097708(intracellular vesicle);GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0030855(epithelial cell differentiation);GO:0055072(iron ion homeostasis);GO:0046951(ketone body biosynthetic process);GO:0003858(3-hydroxybutyrate dehydrogenase activity);GO:0016628(oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor);GO:0051287(NAD binding);GO:0006635(fatty acid beta-oxidation);GO:0019290(siderophore biosynthetic process);GO:0042168(heme metabolic process);GO:0008667(2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase activity);GO:0055114(oxidation-reduction process)","00650(Butanoate metabolism);00072(Synthesis and degradation of ketone bodies);00072(Synthesis and degradation of ketone bodies)","K00019","EC:1.1.1.30","solute carrier family 9 member B2 [Source:HGNC Symbol;Acc:HGNC:25143];3-hydroxybutyrate dehydrogenase 2 [Source:HGNC Symbol;Acc:HGNC:32389]",{"v":0.838863704186603,"d":"0.84"},{"v":0.356371651196172,"d":"0.36"},{"v":2.35390133129538,"d":"2.35"},{"v":1.23505384805935,"d":"1.24"},{"v":0.0621796882005104,"d":"0.06"},{"v":0.717898183423342,"d":"0.72"},"up","no"]
["MSTRG.5252","TLE3","ENST00000557997;ENST00000557907;ENST00000558939;ENST00000451782;ENST00000557815;ENST00000558379;ENST00000557919;ENST00000558201;ENST00000557984;ENST00000627388;ENST00000560589;ENST00000559048;ENST00000537387;ENST00000560525;ENST00000560939;ENST00000561453;ENST00000539550;ENST00000317509;ENST00000559191;ENST00000559929;ENST00000560996;ENST00000559826;ENST00000542329;ENST00000559608;ENST00000440567","GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0016055(Wnt signaling pathway);GO:0005515(protein binding);GO:0007165(signal transduction);GO:1904837(beta-catenin-TCF complex assembly);GO:0009887(animal organ morphogenesis);GO:0009887(animal organ morphogenesis)","NA","NA","NA","transducin like enhancer of split 3 [Source:HGNC Symbol;Acc:HGNC:11839]",{"v":4.45034878518284,"d":"4.45"},{"v":10.6850408259459,"d":"10.69"},{"v":0.416502740389751,"d":"0.42"},{"v":-1.26360210701875,"d":"-1.26"},{"v":0.0624495297070994,"d":"0.06"},{"v":0.720323023690509,"d":"0.72"},"down","no"]
["ENSG00000166801","FAM111A","ENST00000528737;ENST00000420244;ENST00000531676;ENST00000529985;ENST00000527629;ENST00000529358;ENST00000531147;ENST00000361723;ENST00000533703;ENST00000532790","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0001650(fibrillar center);GO:0006260(DNA replication);GO:0051607(defense response to virus);GO:0005515(protein binding);GO:0045071(negative regulation of viral genome replication);GO:0016032(viral process);GO:0000785(chromatin);GO:0000785(chromatin)","NA","NA","NA","family with sequence similarity 111 member A [Source:HGNC Symbol;Acc:HGNC:24725]",{"v":1.1697226386927,"d":"1.17"},{"v":2.82567974698795,"d":"2.83"},{"v":0.413961504285676,"d":"0.41"},{"v":-1.27243148213471,"d":"-1.27"},{"v":0.0626253894864167,"d":"0.06"},{"v":0.720984000695276,"d":"0.72"},"down","no"]
["ENSG00000182685","BRICD5","ENST00000566018;ENST00000562360;ENST00000566795;ENST00000328540","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005515(protein binding);GO:0005615(extracellular space);GO:0042127(regulation of cell proliferation);GO:0042127(regulation of cell proliferation)","NA","NA","NA","BRICHOS domain containing 5 [Source:HGNC Symbol;Acc:HGNC:28309]",{"v":0.311014503600576,"d":"0.31"},{"v":0.811066569371099,"d":"0.81"},{"v":0.383463596387331,"d":"0.38"},{"v":-1.38283847101656,"d":"-1.38"},{"v":0.062626579033986,"d":"0.06"},{"v":0.720984000695276,"d":"0.72"},"down","no"]
["ENSG00000165288","BRWD3","ENST00000373275;ENST00000487313;ENST00000497335;ENST00000473691;ENST00000478415","GO:0005634(nucleus);GO:0007010(cytoskeleton organization);GO:0008360(regulation of cell shape);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0006357(regulation of transcription from RNA polymerase II promoter)","NA","NA","NA","bromodomain and WD repeat domain containing 3 [Source:HGNC Symbol;Acc:HGNC:17342]",{"v":1.91003022869072,"d":"1.91"},{"v":4.58589638868757,"d":"4.59"},{"v":0.416500955713338,"d":"0.42"},{"v":-1.26360828884921,"d":"-1.26"},{"v":0.0627908439001812,"d":"0.06"},{"v":0.721806720823623,"d":"0.72"},"down","no"]
["MSTRG.13928","CAPZA2","ENST00000361183;ENST00000464223;ENST00000484325;MSTRG.13928.4;ENST00000628758;ENST00000465607;ENST00000414148;ENST00000464669;ENST00000426421;ENST00000490693;ENST00000496161","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0003779(actin binding);GO:0051016(barbed-end actin filament capping);GO:0051693(actin filament capping);GO:0008290(F-actin capping protein complex);GO:0005576(extracellular region);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0005903(brush border);GO:0030863(cortical cytoskeleton);GO:0045087(innate immune response);GO:0019886(antigen processing and presentation of exogenous peptide antigen via MHC class II);GO:0006888(ER to Golgi vesicle-mediated transport);GO:0006461(protein complex assembly);GO:0006928(movement of cell or subcellular component);GO:0015629(actin cytoskeleton);GO:0007596(blood coagulation);GO:0007596(blood coagulation)","04144(Endocytosis);04144(Endocytosis)","K10364","NA","capping actin protein of muscle Z-line alpha subunit 2 [Source:HGNC Symbol;Acc:HGNC:1490]",{"v":3.46993965839763,"d":"3.47"},{"v":8.33513824498516,"d":"8.34"},{"v":0.416302592279777,"d":"0.42"},{"v":-1.26429555284561,"d":"-1.26"},{"v":0.0628179242171697,"d":"0.06"},{"v":0.721806720823623,"d":"0.72"},"down","no"]
["MSTRG.14620","AC067930.6;AC067930.2","ENST00000623257;ENST00000529247","NA","NA","NA","NA",null,{"v":0.601097,"d":"0.60"},{"v":0.251061,"d":"0.25"},{"v":2.39422690103202,"d":"2.39"},{"v":1.25955988305908,"d":"1.26"},{"v":0.0629715971702271,"d":"0.06"},{"v":0.722882719851167,"d":"0.72"},"up","no"]
["MSTRG.12901","AGPAT1;MIR6721","ENST00000375107;ENST00000617181;ENST00000476663;ENST00000395499;ENST00000336984","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005783(endoplasmic reticulum);GO:0016740(transferase activity);GO:0016746(transferase activity, transferring acyl groups);GO:0006629(lipid metabolic process);GO:0008152(metabolic process);GO:0005789(endoplasmic reticulum membrane);GO:0008654(phospholipid biosynthetic process);GO:0005515(protein binding);GO:0003841(1-acylglycerol-3-phosphate O-acyltransferase activity);GO:0016024(CDP-diacylglycerol biosynthetic process);GO:0031325(positive regulation of cellular metabolic process);GO:0006654(phosphatidic acid biosynthetic process);GO:0001819(positive regulation of cytokine production);GO:0001961(positive regulation of cytokine-mediated signaling pathway);GO:0006644(phospholipid metabolic process);GO:0006644(phospholipid metabolic process)","00561(Glycerolipid metabolism);00564(Glycerophospholipid metabolism);04072(Phospholipase D signaling pathway);04975(Fat digestion and absorption);04975(Fat digestion and absorption)","K13509","EC:2.3.1.51","1-acylglycerol-3-phosphate O-acyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:324];microRNA 6721 [Source:HGNC Symbol;Acc:HGNC:50049]",{"v":20.0983256098679,"d":"20.10"},{"v":8.7040488619574,"d":"8.70"},{"v":2.30907775549276,"d":"2.31"},{"v":1.20731675499815,"d":"1.21"},{"v":0.063171255038452,"d":"0.06"},{"v":0.724484050640989,"d":"0.72"},"up","no"]
["MSTRG.14761","RGP1","ENST00000378078;ENST00000496906","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0005085(guanyl-nucleotide exchange factor activity);GO:0043547(positive regulation of GTPase activity);GO:0017112(Rab guanyl-nucleotide exchange factor activity);GO:0061024(membrane organization);GO:0043234(protein complex);GO:0042147(retrograde transport, endosome to Golgi);GO:0032588(trans-Golgi network membrane);GO:0000139(Golgi membrane);GO:0017137(Rab GTPase binding);GO:1903363(negative regulation of cellular protein catabolic process);GO:0034066(RIC1-RGP1 guanyl-nucleotide exchange factor complex);GO:0034066(RIC1-RGP1 guanyl-nucleotide exchange factor complex)","NA","NA","NA","RGP1 homolog, RAB6A GEF complex partner 1 [Source:HGNC Symbol;Acc:HGNC:21965]",{"v":4.38473642889264,"d":"4.38"},{"v":1.89632454890388,"d":"1.90"},{"v":2.31222890165458,"d":"2.31"},{"v":1.20928422609784,"d":"1.21"},{"v":0.0633394928141411,"d":"0.06"},{"v":0.725722333461358,"d":"0.73"},"up","no"]
["MSTRG.3688","SSH1","ENST00000326495;ENST00000546812;ENST00000546433;ENST00000547381;ENST00000548522;ENST00000326470;ENST00000547862;ENST00000551165","GO:0005737(cytoplasm);GO:0016787(hydrolase activity);GO:0003779(actin binding);GO:0004725(protein tyrosine phosphatase activity);GO:0008138(protein tyrosine/serine/threonine phosphatase activity);GO:0016791(phosphatase activity);GO:0006470(protein dephosphorylation);GO:0016311(dephosphorylation);GO:0035335(peptidyl-tyrosine dephosphorylation);GO:0005886(plasma membrane);GO:0004721(phosphoprotein phosphatase activity);GO:0030036(actin cytoskeleton organization);GO:0005856(cytoskeleton);GO:0042995(cell projection);GO:0005515(protein binding);GO:0030496(midbody);GO:0030027(lamellipodium);GO:0032154(cleavage furrow);GO:0050770(regulation of axonogenesis);GO:0000902(cell morphogenesis);GO:0071318(cellular response to ATP);GO:0010591(regulation of lamellipodium assembly);GO:0008064(regulation of actin polymerization or depolymerization);GO:0032268(regulation of cellular protein metabolic process);GO:0031915(positive regulation of synaptic plasticity);GO:0098976(excitatory chemical synaptic transmission);GO:1901216(positive regulation of neuron death);GO:1904719(positive regulation of AMPA glutamate receptor clustering);GO:1904754(positive regulation of vascular associated smooth muscle cell migration);GO:2000463(positive regulation of excitatory postsynaptic potential);GO:0005829(cytosol);GO:0030426(growth cone);GO:0031252(cell leading edge);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016021(integral component of membrane)","04810(Regulation of actin cytoskeleton);04360(Axon guidance);04360(Axon guidance)","K05766","EC:3.1.3.16;EC:3.1.3.48","slingshot protein phosphatase 1 [Source:HGNC Symbol;Acc:HGNC:30579]",{"v":1.34726449290367,"d":"1.35"},{"v":3.22601958697292,"d":"3.23"},{"v":0.417624399536846,"d":"0.42"},{"v":-1.2597220916422,"d":"-1.26"},{"v":0.0638724052199065,"d":"0.06"},{"v":0.731132608040033,"d":"0.73"},"down","no"]
["MSTRG.12861","NFKBIL1","ENST00000376148;ENST00000496233;ENST00000376146;ENST00000376145;ENST00000473655","GO:0005634(nucleus);GO:0005515(protein binding);GO:0071222(cellular response to lipopolysaccharide);GO:0032088(negative regulation of NF-kappaB transcription factor activity);GO:0032720(negative regulation of tumor necrosis factor production);GO:0042994(cytoplasmic sequestering of transcription factor);GO:0031665(negative regulation of lipopolysaccharide-mediated signaling pathway);GO:0034122(negative regulation of toll-like receptor signaling pathway);GO:0007249(I-kappaB kinase/NF-kappaB signaling);GO:0005829(cytosol);GO:0005829(cytosol)","NA","NA","NA","NFKB inhibitor like 1 [Source:HGNC Symbol;Acc:HGNC:7800]",{"v":3.02768967734682,"d":"3.03"},{"v":1.29221465430017,"d":"1.29"},{"v":2.34302379041394,"d":"2.34"},{"v":1.22837160300086,"d":"1.23"},{"v":0.0639479081079329,"d":"0.06"},{"v":0.731301718362515,"d":"0.73"},"up","no"]
["MSTRG.14199","CTSB","ENST00000353047;ENST00000531089;ENST00000530640;ENST00000531551;ENST00000533455;ENST00000526481;ENST00000532392;ENST00000530296;ENST00000532656;MSTRG.14199.1;ENST00000345125;ENST00000525076;ENST00000524500;ENST00000524654;ENST00000530624;ENST00000530290;ENST00000532370;ENST00000533110;ENST00000527243;ENST00000420692;ENST00000525315;ENST00000533572;ENST00000505496;ENST00000534510;ENST00000534636;ENST00000526195;ENST00000534382;ENST00000528965;ENST00000453527;ENST00000532409","GO:0008234(cysteine-type peptidase activity);GO:0006508(proteolysis);GO:0005615(extracellular space);GO:0043231(intracellular membrane-bounded organelle);GO:0005730(nucleolus);GO:0016787(hydrolase activity);GO:0005515(protein binding);GO:0008233(peptidase activity);GO:0005576(extracellular region);GO:0042470(melanosome);GO:0048471(perinuclear region of cytoplasm);GO:0004197(cysteine-type endopeptidase activity);GO:0046697(decidualization);GO:0046718(viral entry into host cell);GO:0050790(regulation of catalytic activity);GO:0005739(mitochondrion);GO:0005764(lysosome);GO:0004252(serine-type endopeptidase activity);GO:0070062(extracellular exosome);GO:0030574(collagen catabolic process);GO:0043312(neutrophil degranulation);GO:0042981(regulation of apoptotic process);GO:0005622(intracellular);GO:0002224(toll-like receptor signaling pathway);GO:1904813(ficolin-1-rich granule lumen);GO:0030855(epithelial cell differentiation);GO:0005518(collagen binding);GO:0043394(proteoglycan binding);GO:0051603(proteolysis involved in cellular protein catabolic process);GO:0097067(cellular response to thyroid hormone stimulus);GO:0036021(endolysosome lumen);GO:0036021(endolysosome lumen)","04142(Lysosome);04140(Autophagy - animal);04210(Apoptosis);04621(NOD-like receptor signaling pathway);04612(Antigen processing and presentation);04924(Renin secretion);04924(Renin secretion)","K01363","EC:3.4.22.1","cathepsin B [Source:HGNC Symbol;Acc:HGNC:2527]",{"v":19.832276257427,"d":"19.83"},{"v":47.3108752384505,"d":"47.31"},{"v":0.419190643958092,"d":"0.42"},{"v":-1.25432157759667,"d":"-1.25"},{"v":0.0641783302413429,"d":"0.06"},{"v":0.733240467520163,"d":"0.73"},"down","no"]
["MSTRG.8205","CEACAM1","ENST00000161559;ENST00000377806;ENST00000488639;ENST00000465051;ENST00000358394;ENST00000352591;ENST00000599389;ENST00000344391;ENST00000403136","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0007155(cell adhesion);GO:0003779(actin binding);GO:0042803(protein homodimerization activity);GO:0005886(plasma membrane);GO:0042995(cell projection);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0030054(cell junction);GO:0031410(cytoplasmic vesicle);GO:0007229(integrin-mediated signaling pathway);GO:0050900(leukocyte migration);GO:0005887(integral component of plasma membrane);GO:0003674(molecular_function);GO:0070062(extracellular exosome);GO:0005912(adherens junction);GO:0043312(neutrophil degranulation);GO:0035579(specific granule membrane);GO:0070821(tertiary granule membrane);GO:0001558(regulation of cell growth);GO:0030334(regulation of cell migration);GO:0009925(basal plasma membrane);GO:0016328(lateral plasma membrane);GO:0016324(apical plasma membrane);GO:0019903(protein phosphatase binding);GO:0009986(cell surface);GO:0016477(cell migration);GO:0043116(negative regulation of vascular permeability);GO:0032869(cellular response to insulin stimulus);GO:0005911(cell-cell junction);GO:0001525(angiogenesis);GO:0031528(microvillus membrane);GO:0007156(homophilic cell adhesion via plasma membrane adhesion molecules);GO:0044319(wound healing, spreading of cells);GO:0006469(negative regulation of protein kinase activity);GO:0019900(kinase binding);GO:0001568(blood vessel development);GO:0015721(bile acid and bile salt transport);GO:0030658(transport vesicle membrane);GO:0046983(protein dimerization activity);GO:0014066(regulation of phosphatidylinositol 3-kinase signaling);GO:0045717(negative regulation of fatty acid biosynthetic process);GO:0031005(filamin binding);GO:0070372(regulation of ERK1 and ERK2 cascade);GO:0042101(T cell receptor complex);GO:0050860(negative regulation of T cell receptor signaling pathway);GO:1990782(protein tyrosine kinase binding);GO:0001915(negative regulation of T cell mediated cytotoxicity);GO:0030853(negative regulation of granulocyte differentiation);GO:0015125(bile acid transmembrane transporter activity);GO:0002859(negative regulation of natural killer cell mediated cytotoxicity directed against tumor cell target);GO:0010594(regulation of endothelial cell migration);GO:0032692(negative regulation of interleukin-1 production);GO:0035726(common myeloid progenitor cell proliferation);GO:0038016(insulin receptor internalization);GO:0038158(granulocyte colony-stimulating factor signaling pathway);GO:0042058(regulation of epidermal growth factor receptor signaling pathway);GO:0043318(negative regulation of cytotoxic T cell degranulation);GO:0045601(regulation of endothelial cell differentiation);GO:0051055(negative regulation of lipid biosynthetic process);GO:0060312(regulation of blood vessel remodeling);GO:0090331(negative regulation of platelet aggregation);GO:0098742(cell-cell adhesion via plasma-membrane adhesion molecules);GO:1901143(insulin catabolic process);GO:1903385(regulation of homophilic cell adhesion);GO:1903670(regulation of sprouting angiogenesis);GO:2000346(negative regulation of hepatocyte proliferation);GO:2001214(positive regulation of vasculogenesis);GO:2001214(positive regulation of vasculogenesis)","NA","NA","NA","carcinoembryonic antigen related cell adhesion molecule 1 [Source:HGNC Symbol;Acc:HGNC:1814]",{"v":1.19765065821868,"d":"1.20"},{"v":2.88561925941347,"d":"2.89"},{"v":0.415041123083616,"d":"0.42"},{"v":-1.26867380630845,"d":"-1.27"},{"v":0.0642442291151302,"d":"0.06"},{"v":0.733297636970994,"d":"0.73"},"down","no"]
["MSTRG.4530","FAM161B;AC005480.1","ENST00000286544;ENST00000554009;ENST00000555916","NA","NA","NA","NA","family with sequence similarity 161 member B [Source:HGNC Symbol;Acc:HGNC:19854]",{"v":0.613979079265458,"d":"0.61"},{"v":0.260712850999535,"d":"0.26"},{"v":2.35500120884549,"d":"2.36"},{"v":1.23572780038793,"d":"1.24"},{"v":0.0643781113376092,"d":"0.06"},{"v":0.734129940082851,"d":"0.73"},"up","no"]
["ENSG00000237190","CDKN2AIPNL","ENST00000458198;ENST00000395009","GO:0005730(nucleolus);GO:0007165(signal transduction);GO:0005654(nucleoplasm);GO:0005654(nucleoplasm)","NA","NA","NA","CDKN2A interacting protein N-terminal like [Source:HGNC Symbol;Acc:HGNC:30545]",{"v":1.5480097404667,"d":"1.55"},{"v":0.650903988047809,"d":"0.65"},{"v":2.37824589938293,"d":"2.38"},{"v":1.24989789064267,"d":"1.25"},{"v":0.0645217592680017,"d":"0.06"},{"v":0.735052197312652,"d":"0.74"},"up","no"]
["ENSG00000130598","TNNI2","ENST00000381905;ENST00000468473;ENST00000617947;ENST00000381911","GO:0005634(nucleus);GO:0003779(actin binding);GO:0045893(positive regulation of transcription, DNA-templated);GO:0005861(troponin complex);GO:0005515(protein binding);GO:0005829(cytosol);GO:0003009(skeletal muscle contraction);GO:0030049(muscle filament sliding);GO:0060048(cardiac muscle contraction);GO:0031014(troponin T binding);GO:0006937(regulation of muscle contraction);GO:0006937(regulation of muscle contraction)","NA","NA","NA","troponin I2, fast skeletal type [Source:HGNC Symbol;Acc:HGNC:11946]",{"v":1.12719670609982,"d":"1.13"},{"v":2.80169243345656,"d":"2.80"},{"v":0.402327069395391,"d":"0.40"},{"v":-1.31355928615901,"d":"-1.31"},{"v":0.0645810683239317,"d":"0.06"},{"v":0.735052197312652,"d":"0.74"},"down","no"]
["MSTRG.2530","CDC42EP2","ENST00000279249;ENST00000533419","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0043547(positive regulation of GTPase activity);GO:0015630(microtubule cytoskeleton);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0005096(GTPase activator activity);GO:0012505(endomembrane system);GO:0031274(positive regulation of pseudopodium assembly);GO:0007266(Rho protein signal transduction);GO:0008360(regulation of cell shape);GO:0030036(actin cytoskeleton organization);GO:0001515(opioid peptide activity);GO:0017049(GTP-Rho binding);GO:0007015(actin filament organization);GO:0030838(positive regulation of actin filament polymerization);GO:0031334(positive regulation of protein complex assembly);GO:0031334(positive regulation of protein complex assembly)","NA","NA","NA","CDC42 effector protein 2 [Source:HGNC Symbol;Acc:HGNC:16263]",{"v":6.56240329046763,"d":"6.56"},{"v":15.6704017783273,"d":"15.67"},{"v":0.418776964579406,"d":"0.42"},{"v":-1.25574600792202,"d":"-1.26"},{"v":0.0646849599955408,"d":"0.06"},{"v":0.73518496769964,"d":"0.74"},"down","no"]
["ENSG00000104043","ATP8B4","ENST00000559726;ENST00000560161;ENST00000558959;ENST00000558203;ENST00000557955;ENST00000558906;ENST00000558024;ENST00000560437;ENST00000561385;ENST00000560354;ENST00000284509;ENST00000559829;ENST00000558458","GO:0016021(integral component of membrane);GO:0005524(ATP binding);GO:0000287(magnesium ion binding);GO:0004012(phospholipid-translocating ATPase activity);GO:0015914(phospholipid transport);GO:0045332(phospholipid translocation);GO:0006810(transport);GO:0016020(membrane);GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0016787(hydrolase activity);GO:0005794(Golgi apparatus);GO:0005886(plasma membrane);GO:0006869(lipid transport);GO:0043312(neutrophil degranulation);GO:0035579(specific granule membrane);GO:0070821(tertiary granule membrane);GO:0007030(Golgi organization);GO:0007030(Golgi organization)","NA","NA","NA","ATPase phospholipid transporting 8B4 (putative) [Source:HGNC Symbol;Acc:HGNC:13536]",{"v":0.374722316177148,"d":"0.37"},{"v":0.900028537519565,"d":"0.90"},{"v":0.416344927472927,"d":"0.42"},{"v":-1.26414884785504,"d":"-1.26"},{"v":0.0647148368843729,"d":"0.06"},{"v":0.73518496769964,"d":"0.74"},"down","no"]
["MSTRG.14266","EXTL3","ENST00000523271;ENST00000220562;ENST00000522725;ENST00000520679;ENST00000523149;ENST00000520940;ENST00000519886;ENST00000517738;ENST00000521473","GO:0016021(integral component of membrane);GO:0016757(transferase activity, transferring glycosyl groups);GO:0016020(membrane);GO:0046872(metal ion binding);GO:0016740(transferase activity);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0036498(IRE1-mediated unfolded protein response);GO:0001888(glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity);GO:0004872(receptor activity);GO:0015012(heparan sulfate proteoglycan biosynthetic process);GO:0030307(positive regulation of cell growth);GO:0030307(positive regulation of cell growth)","00534(Glycosaminoglycan biosynthesis - heparan sulfate / heparin);00534(Glycosaminoglycan biosynthesis - heparan sulfate / heparin)","K02370","EC:2.4.1.223;EC:2.4.1.224","exostosin like glycosyltransferase 3 [Source:HGNC Symbol;Acc:HGNC:3518]",{"v":1.29931325506808,"d":"1.30"},{"v":3.09730044863843,"d":"3.10"},{"v":0.419498617139082,"d":"0.42"},{"v":-1.25326204000266,"d":"-1.25"},{"v":0.0652463425625551,"d":"0.07"},{"v":0.739443719773594,"d":"0.74"},"down","no"]
["MSTRG.5879","VKORC1;PRSS53;AC135050.2","ENST00000394975;ENST00000486499;ENST00000420057;ENST00000394971;ENST00000492427;ENST00000319788;ENST00000300851;ENST00000533518;ENST00000354895","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0060348(bone development);GO:0007596(blood coagulation);GO:0017144(drug metabolic process);GO:0042373(vitamin K metabolic process);GO:0048038(quinone binding);GO:0047057(vitamin-K-epoxide reductase (warfarin-sensitive) activity);GO:0017187(peptidyl-glutamic acid carboxylation);GO:0016787(hydrolase activity);GO:0008233(peptidase activity);GO:0006508(proteolysis);GO:0005576(extracellular region);GO:0004252(serine-type endopeptidase activity);GO:0008236(serine-type peptidase activity);GO:0005737(cytoplasm);GO:0047058(vitamin-K-epoxide reductase (warfarin-insensitive) activity);GO:0010243(response to organonitrogen compound);GO:0014070(response to organic cyclic compound);GO:0030193(regulation of blood coagulation);GO:0046677(response to antibiotic);GO:0043231(intracellular membrane-bounded organelle);GO:0017187(peptidyl-glutamic acid carboxylation)","00130(Ubiquinone and other terpenoid-quinone biosynthesis);00130(Ubiquinone and other terpenoid-quinone biosynthesis)","K05357","EC:1.17.4.4","vitamin K epoxide reductase complex subunit 1 [Source:HGNC Symbol;Acc:HGNC:23663];protease, serine 53 [Source:HGNC Symbol;Acc:HGNC:34407]",{"v":0.938869875325013,"d":"0.94"},{"v":2.24836640665627,"d":"2.25"},{"v":0.417578679589544,"d":"0.42"},{"v":-1.25988004111092,"d":"-1.26"},{"v":0.0653195727901822,"d":"0.07"},{"v":0.739443719773594,"d":"0.74"},"down","no"]
["MSTRG.12325","PCBD2;CATSPER3","ENST00000512783;ENST00000282611;ENST00000504352;ENST00000254908","GO:0016829(lyase activity);GO:0055114(oxidation-reduction process);GO:0005515(protein binding);GO:0045893(positive regulation of transcription, DNA-templated);GO:0005575(cellular_component);GO:0006729(tetrahydrobiopterin biosynthetic process);GO:0008124(4-alpha-hydroxytetrahydrobiopterin dehydratase activity);GO:0004505(phenylalanine 4-monooxygenase activity);GO:0051289(protein homotetramerization);GO:0051291(protein heterooligomerization);GO:0005634(nucleus);GO:0005739(mitochondrion);GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0055085(transmembrane transport);GO:0005216(ion channel activity);GO:0006811(ion transport);GO:0031514(motile cilium);GO:0005244(voltage-gated ion channel activity);GO:0034765(regulation of ion transmembrane transport);GO:0005886(plasma membrane);GO:0042995(cell projection);GO:0006816(calcium ion transport);GO:0007275(multicellular organism development);GO:0030154(cell differentiation);GO:0005262(calcium channel activity);GO:0070588(calcium ion transmembrane transport);GO:0007283(spermatogenesis);GO:0005929(cilium);GO:0035036(sperm-egg recognition);GO:0086010(membrane depolarization during action potential);GO:0034220(ion transmembrane transport);GO:0036128(CatSper complex);GO:0005261(cation channel activity);GO:0032570(response to progesterone);GO:0005245(voltage-gated calcium channel activity);GO:0006814(sodium ion transport);GO:0030317(flagellated sperm motility);GO:0048240(sperm capacitation);GO:0001669(acrosomal vesicle);GO:0005783(endoplasmic reticulum);GO:0005739(mitochondrion)","00790(Folate biosynthesis);00790(Folate biosynthesis)","K01724","EC:4.2.1.96","pterin-4 alpha-carbinolamine dehydratase 2 [Source:HGNC Symbol;Acc:HGNC:24474];cation channel sperm associated 3 [Source:HGNC Symbol;Acc:HGNC:20819]",{"v":0.388670834781545,"d":"0.39"},{"v":0.165275586219557,"d":"0.17"},{"v":2.35165304006378,"d":"2.35"},{"v":1.23367522246027,"d":"1.23"},{"v":0.0653796370187268,"d":"0.07"},{"v":0.739443719773594,"d":"0.74"},"up","no"]
["MSTRG.7824","PLPPR2","ENST00000591608;ENST00000251473;ENST00000587801;ENST00000588360;ENST00000586380;ENST00000591329;ENST00000588196;ENST00000586431","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016787(hydrolase activity);GO:0005887(integral component of plasma membrane);GO:0007165(signal transduction);GO:0008195(phosphatidate phosphatase activity);GO:0042577(lipid phosphatase activity);GO:0006644(phospholipid metabolic process);GO:0046839(phospholipid dephosphorylation);GO:0046839(phospholipid dephosphorylation)","NA","NA","NA","phospholipid phosphatase related 2 [Source:HGNC Symbol;Acc:HGNC:29566]",{"v":10.2801193067522,"d":"10.28"},{"v":24.4562217296059,"d":"24.46"},{"v":0.420347812528516,"d":"0.42"},{"v":-1.25034452948806,"d":"-1.25"},{"v":0.0653994275148846,"d":"0.07"},{"v":0.739443719773594,"d":"0.74"},"down","no"]
["MSTRG.379","RNF19B","ENST00000356990;ENST00000373456;ENST00000235150","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0046872(metal ion binding);GO:0005829(cytosol);GO:0016740(transferase activity);GO:0016567(protein ubiquitination);GO:0004842(ubiquitin-protein transferase activity);GO:0005515(protein binding);GO:0002376(immune system process);GO:0002250(adaptive immune response);GO:0000151(ubiquitin ligase complex);GO:0061630(ubiquitin protein ligase activity);GO:0000209(protein polyubiquitination);GO:0042787(protein ubiquitination involved in ubiquitin-dependent protein catabolic process);GO:0032436(positive regulation of proteasomal ubiquitin-dependent protein catabolic process);GO:0031624(ubiquitin conjugating enzyme binding);GO:0044194(cytolytic granule);GO:0044194(cytolytic granule)","NA","NA","NA","ring finger protein 19B [Source:HGNC Symbol;Acc:HGNC:26886]",{"v":9.17385502375479,"d":"9.17"},{"v":21.8306903111111,"d":"21.83"},{"v":0.420227436375917,"d":"0.42"},{"v":-1.25075773718079,"d":"-1.25"},{"v":0.0654099402091022,"d":"0.07"},{"v":0.739443719773594,"d":"0.74"},"down","no"]
["MSTRG.1682","ALOX5","ENST00000374391;ENST00000475300;ENST00000493336;ENST00000612635;ENST00000498461;ENST00000481117;ENST00000542434;ENST00000483623","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0046872(metal ion binding);GO:0005654(nucleoplasm);GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0005829(cytosol);GO:0005506(iron ion binding);GO:0005515(protein binding);GO:0005615(extracellular space);GO:0051213(dioxygenase activity);GO:0005576(extracellular region);GO:0016702(oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen);GO:0019370(leukotriene biosynthetic process);GO:0043312(neutrophil degranulation);GO:0031965(nuclear membrane);GO:0034774(secretory granule lumen);GO:1904813(ficolin-1-rich granule lumen);GO:0016363(nuclear matrix);GO:0005635(nuclear envelope);GO:0019372(lipoxygenase pathway);GO:0004051(arachidonate 5-lipoxygenase activity);GO:0002540(leukotriene production involved in inflammatory response);GO:0006691(leukotriene metabolic process);GO:0006954(inflammatory response);GO:2001300(lipoxin metabolic process);GO:0005641(nuclear envelope lumen);GO:0005641(nuclear envelope lumen)","00590(Arachidonic acid metabolism);04664(Fc epsilon RI signaling pathway);04913(Ovarian Steroidogenesis);04726(Serotonergic synapse);05145(Toxoplasmosis);05145(Toxoplasmosis)","K00461","EC:1.13.11.34","arachidonate 5-lipoxygenase [Source:HGNC Symbol;Acc:HGNC:435]",{"v":20.9044844538874,"d":"20.90"},{"v":49.6678528823056,"d":"49.67"},{"v":0.420885607908666,"d":"0.42"},{"v":-1.24849991700642,"d":"-1.25"},{"v":0.0654581469256479,"d":"0.07"},{"v":0.739443719773594,"d":"0.74"},"down","no"]
["MSTRG.11318","AC112491.1","ENST00000602890","NA","NA","NA","NA",null,{"v":11.31738,"d":"11.32"},{"v":4.753333,"d":"4.75"},{"v":2.380935650837,"d":"2.38"},{"v":1.25152862964946,"d":"1.25"},{"v":0.065833854344318,"d":"0.07"},{"v":0.741978800548696,"d":"0.74"},"up","no"]
["MSTRG.1027","ZBTB7B","ENST00000368426;ENST00000417934;ENST00000535420;ENST00000292176;ENST00000487542;ENST00000461530;ENST00000483226","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0005654(nucleoplasm);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0007275(multicellular organism development);GO:0030154(cell differentiation);GO:0006366(transcription from RNA polymerase II promoter);GO:0007398(ectoderm development);GO:0010628(positive regulation of gene expression);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:0001077(transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0042803(protein homodimerization activity);GO:0043370(regulation of CD4-positive, alpha-beta T cell differentiation);GO:0043376(regulation of CD8-positive, alpha-beta T cell differentiation);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0045944(positive regulation of transcription from RNA polymerase II promoter)","NA","NA","NA","zinc finger and BTB domain containing 7B [Source:HGNC Symbol;Acc:HGNC:18668]",{"v":9.33352547408785,"d":"9.33"},{"v":22.1604126376946,"d":"22.16"},{"v":0.42118012993186,"d":"0.42"},{"v":-1.2474907191243,"d":"-1.25"},{"v":0.0658608821558024,"d":"0.07"},{"v":0.741978800548696,"d":"0.74"},"down","no"]
["ENSG00000204977","TRIM13","ENST00000378182;ENST00000457662;ENST00000378183;ENST00000442421;ENST00000478111;ENST00000420995","GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0005622(intracellular);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016740(transferase activity);GO:0016567(protein ubiquitination);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005515(protein binding);GO:0004871(signal transducer activity);GO:0044322(endoplasmic reticulum quality control compartment);GO:0045087(innate immune response);GO:0007165(signal transduction);GO:0043123(positive regulation of I-kappaB kinase/NF-kappaB signaling);GO:0030433(ubiquitin-dependent ERAD pathway);GO:0051092(positive regulation of NF-kappaB transcription factor activity);GO:0004842(ubiquitin-protein transferase activity);GO:1904264(ubiquitin protein ligase activity involved in ERAD pathway);GO:1904380(endoplasmic reticulum mannose trimming);GO:0010332(response to gamma radiation);GO:0043161(proteasome-mediated ubiquitin-dependent protein catabolic process);GO:0009653(anatomical structure morphogenesis);GO:0097038(perinuclear endoplasmic reticulum);GO:0010942(positive regulation of cell death);GO:0051865(protein autoubiquitination);GO:0016239(positive regulation of macroautophagy);GO:0032897(negative regulation of viral transcription);GO:1902187(negative regulation of viral release from host cell);GO:0005737(cytoplasm);GO:0005737(cytoplasm)","NA","NA","NA","tripartite motif containing 13 [Source:HGNC Symbol;Acc:HGNC:9976]",{"v":0.320177894059406,"d":"0.32"},{"v":0.781518487252475,"d":"0.78"},{"v":0.409686909883643,"d":"0.41"},{"v":-1.28740629762114,"d":"-1.29"},{"v":0.0658674088844508,"d":"0.07"},{"v":0.741978800548696,"d":"0.74"},"down","no"]
["ENSG00000174255","ZNF80","ENST00000308095;ENST00000482457;ENST00000619534","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0003677(DNA binding)","NA","NA","NA","zinc finger protein 80 [Source:HGNC Symbol;Acc:HGNC:13155]",{"v":0.21992905834464,"d":"0.22"},{"v":0.558782301899593,"d":"0.56"},{"v":0.393586299345892,"d":"0.39"},{"v":-1.34524809323906,"d":"-1.35"},{"v":0.0661807691988085,"d":"0.07"},{"v":0.744811983824348,"d":"0.74"},"down","no"]
["MSTRG.672","GNG5","ENST00000370645;ENST00000370641;ENST00000487806","GO:0016020(membrane);GO:0007186(G-protein coupled receptor signaling pathway);GO:0004871(signal transducer activity);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0007165(signal transduction);GO:0005834(heterotrimeric G-protein complex);GO:0003924(GTPase activity);GO:0070062(extracellular exosome);GO:0071377(cellular response to glucagon stimulus);GO:0030165(PDZ domain binding);GO:0072513(positive regulation of secondary heart field cardioblast proliferation);GO:2000179(positive regulation of neural precursor cell proliferation);GO:0005739(mitochondrion);GO:0031680(G-protein beta/gamma-subunit complex);GO:0031680(G-protein beta/gamma-subunit complex)","04014(Ras signaling pathway);04371(Apelin signaling pathway);04151(PI3K-Akt signaling pathway);04062(Chemokine signaling pathway);04926(Relaxin signaling pathway);04724(Glutamatergic synapse);04727(GABAergic synapse);04725(Cholinergic synapse);04728(Dopaminergic synapse);04726(Serotonergic synapse);04723(Retrograde endocannabinoid signaling);04713(Circadian entrainment);05200(Pathways in cancer);05032(Morphine addiction);05034(Alcoholism);05167(Kaposi's sarcoma-associated herpesvirus infection);05167(Kaposi's sarcoma-associated herpesvirus infection)","K04542","NA","G protein subunit gamma 5 [Source:HGNC Symbol;Acc:HGNC:4408]",{"v":8.37678716726619,"d":"8.38"},{"v":19.9623514640288,"d":"19.96"},{"v":0.419629279765,"d":"0.42"},{"v":-1.25281274895976,"d":"-1.25"},{"v":0.0662941654131541,"d":"0.07"},{"v":0.745391540527733,"d":"0.75"},"down","no"]
["ENSG00000166432","ZMAT1","ENST00000494068;ENST00000488347;ENST00000540921;ENST00000372782;ENST00000458570;ENST00000490757","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0003677(DNA binding);GO:0003723(RNA binding);GO:0002039(p53 binding);GO:0072332(intrinsic apoptotic signaling pathway by p53 class mediator);GO:0072332(intrinsic apoptotic signaling pathway by p53 class mediator)","NA","NA","NA","zinc finger matrin-type 1 [Source:HGNC Symbol;Acc:HGNC:29377]",{"v":0.894457844956082,"d":"0.89"},{"v":0.384627685121107,"d":"0.38"},{"v":2.3255160238256,"d":"2.33"},{"v":1.21755088069851,"d":"1.22"},{"v":0.0665456069026272,"d":"0.07"},{"v":0.7475207073894,"d":"0.75"},"up","no"]
["MSTRG.14846","NINJ1","ENST00000375446;ENST00000461162;ENST00000470314;ENST00000490564;ENST00000489274","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0007155(cell adhesion);GO:0005515(protein binding);GO:0042246(tissue regeneration);GO:0007399(nervous system development);GO:0001954(positive regulation of cell-matrix adhesion);GO:1990384(hyaloid vascular plexus regression);GO:1990384(hyaloid vascular plexus regression)","NA","NA","NA","ninjurin 1 [Source:HGNC Symbol;Acc:HGNC:7824]",{"v":25.091399472432,"d":"25.09"},{"v":59.374658189577,"d":"59.37"},{"v":0.422594423909234,"d":"0.42"},{"v":-1.24265436370435,"d":"-1.24"},{"v":0.0667184962786284,"d":"0.07"},{"v":0.748259006951806,"d":"0.75"},"down","no"]
["ENSG00000215447","BX322557.1","ENST00000400362;ENST00000454115","NA","NA","NA","NA",null,{"v":1.1707795610071,"d":"1.17"},{"v":0.489520939315688,"d":"0.49"},{"v":2.39168433253082,"d":"2.39"},{"v":1.25802698738514,"d":"1.26"},{"v":0.0667726200958266,"d":"0.07"},{"v":0.748259006951806,"d":"0.75"},"up","no"]
["MSTRG.3792","UNC119B","ENST00000344651;ENST00000539658;ENST00000618898","GO:0006810(transport);GO:0015031(protein transport);GO:0042995(cell projection);GO:0005622(intracellular);GO:0008289(lipid binding);GO:0005515(protein binding);GO:0060271(cilium assembly);GO:0005929(cilium);GO:0005829(cytosol);GO:0030030(cell projection organization);GO:0030182(neuron differentiation);GO:0042953(lipoprotein transport);GO:0035869(ciliary transition zone);GO:0035869(ciliary transition zone)","NA","NA","NA","unc-119 lipid binding chaperone B [Source:HGNC Symbol;Acc:HGNC:16488]",{"v":3.56013060096246,"d":"3.56"},{"v":1.55287130625602,"d":"1.55"},{"v":2.29261149112604,"d":"2.29"},{"v":1.19699189468555,"d":"1.20"},{"v":0.0668449579873303,"d":"0.07"},{"v":0.748259006951806,"d":"0.75"},"up","no"]
["ENSG00000040275","SPDL1","ENST00000265295;ENST00000515224;ENST00000629457;ENST00000506574;ENST00000503871;ENST00000508837;ENST00000503209","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0051301(cell division);GO:0005694(chromosome);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0007049(cell cycle);GO:0000922(spindle pole);GO:0005815(microtubule organizing center);GO:0000775(chromosome, centromeric region);GO:0000776(kinetochore);GO:0000777(condensed chromosome kinetochore);GO:0005829(cytosol);GO:0031577(spindle checkpoint);GO:0007062(sister chromatid cohesion);GO:0019899(enzyme binding);GO:0000132(establishment of mitotic spindle orientation);GO:0007080(mitotic metaphase plate congression);GO:0034501(protein localization to kinetochore);GO:0000940(condensed chromosome outer kinetochore);GO:0043515(kinetochore binding);GO:0043515(kinetochore binding)","NA","NA","NA","spindle apparatus coiled-coil protein 1 [Source:HGNC Symbol;Acc:HGNC:26010]",{"v":0.686134331588863,"d":"0.69"},{"v":0.289420422440862,"d":"0.29"},{"v":2.37071843722107,"d":"2.37"},{"v":1.24532432863772,"d":"1.25"},{"v":0.0668598813718771,"d":"0.07"},{"v":0.748259006951806,"d":"0.75"},"up","no"]
["MSTRG.3667","WASHC4","ENST00000550053;ENST00000332180;ENST00000620430;ENST00000548195;ENST00000551224;ENST00000552203;ENST00000550036;ENST00000548534;ENST00000550613;ENST00000547171;ENST00000311317;ENST00000550786","GO:0071203(WASH complex);GO:0006810(transport);GO:0015031(protein transport);GO:0005768(endosome);GO:0005769(early endosome);GO:0016197(endosomal transport);GO:0007032(endosome organization);GO:0031083(BLOC-1 complex);GO:0031083(BLOC-1 complex)","04144(Endocytosis);04144(Endocytosis)","K18465","NA","WASH complex subunit 4 [Source:HGNC Symbol;Acc:HGNC:29174]",{"v":3.10725655170174,"d":"3.11"},{"v":7.35471286035334,"d":"7.35"},{"v":0.4224850936672,"d":"0.42"},{"v":-1.24302765449085,"d":"-1.24"},{"v":0.0669342583984737,"d":"0.07"},{"v":0.748395858527781,"d":"0.75"},"down","no"]
["MSTRG.2495","OTUB1;COX8A;AP000721.1","ENST00000538426;ENST00000301453;ENST00000543988;ENST00000535715;ENST00000314133;ENST00000535140;ENST00000535431;ENST00000447683;ENST00000536443;ENST00000536943","GO:0004843(thiol-dependent ubiquitin-specific protease activity);GO:0016579(protein deubiquitination);GO:0005737(cytoplasm);GO:0016787(hydrolase activity);GO:0005515(protein binding);GO:0008233(peptidase activity);GO:0008234(cysteine-type peptidase activity);GO:0006508(proteolysis);GO:0006281(DNA repair);GO:0006974(cellular response to DNA damage stimulus);GO:0036459(thiol-dependent ubiquitinyl hydrolase activity);GO:0002376(immune system process);GO:0002250(adaptive immune response);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0071108(protein K48-linked deubiquitination);GO:0031625(ubiquitin protein ligase binding);GO:0019784(NEDD8-specific protease activity);GO:0043130(ubiquitin binding);GO:1901315(negative regulation of histone H2A K63-linked ubiquitination);GO:2000780(negative regulation of double-strand break repair);GO:0071347(cellular response to interleukin-1);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005743(mitochondrial inner membrane);GO:0005739(mitochondrion);GO:1902600(hydrogen ion transmembrane transport);GO:0004129(cytochrome-c oxidase activity);GO:0006123(mitochondrial electron transport, cytochrome c to oxygen);GO:0006091(generation of precursor metabolites and energy);GO:0005751(mitochondrial respiratory chain complex IV);GO:0071347(cellular response to interleukin-1)","00190(Oxidative phosphorylation);04260(Cardiac muscle contraction);05010(Alzheimer's disease);05012(Parkinson's disease);05016(Huntington's disease);04932(Non-alcoholic fatty liver disease (NAFLD))","K02273","NA","OTU deubiquitinase, ubiquitin aldehyde binding 1 [Source:HGNC Symbol;Acc:HGNC:23077];cytochrome c oxidase subunit 8A [Source:HGNC Symbol;Acc:HGNC:2294]",{"v":3.57355466797878,"d":"3.57"},{"v":8.46765039859661,"d":"8.47"},{"v":0.422024351474294,"d":"0.42"},{"v":-1.24460184776153,"d":"-1.24"},{"v":0.0671159316956831,"d":"0.07"},{"v":0.749731029201684,"d":"0.75"},"down","no"]
["MSTRG.9189","MARCH7","ENST00000259050;ENST00000539065;MSTRG.9189.4;ENST00000420397;ENST00000478396;ENST00000409175;ENST00000421037;ENST00000409591;ENST00000473749","GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0016740(transferase activity);GO:0016567(protein ubiquitination);GO:0002643(regulation of tolerance induction);GO:0042130(negative regulation of T cell proliferation);GO:0042130(negative regulation of T cell proliferation)","NA","NA","NA","membrane associated ring-CH-type finger 7 [Source:HGNC Symbol;Acc:HGNC:17393]",{"v":7.25134875003973,"d":"7.25"},{"v":17.1415040680121,"d":"17.14"},{"v":0.423028733142008,"d":"0.42"},{"v":-1.24117243685265,"d":"-1.24"},{"v":0.0672658202233958,"d":"0.07"},{"v":0.750708996413468,"d":"0.75"},"down","no"]
["ENSG00000145332","KLHL8","ENST00000273963;ENST00000512111;ENST00000506274;ENST00000504029;ENST00000425278","GO:0005654(nucleoplasm);GO:0016567(protein ubiquitination);GO:0031463(Cul3-RING ubiquitin ligase complex);GO:0004842(ubiquitin-protein transferase activity);GO:0042787(protein ubiquitination involved in ubiquitin-dependent protein catabolic process);GO:0042787(protein ubiquitination involved in ubiquitin-dependent protein catabolic process)","NA","NA","NA","kelch like family member 8 [Source:HGNC Symbol;Acc:HGNC:18644]",{"v":0.943918135164536,"d":"0.94"},{"v":2.24838778528692,"d":"2.25"},{"v":0.419819988945582,"d":"0.42"},{"v":-1.25215723538898,"d":"-1.25"},{"v":0.0673959796594289,"d":"0.07"},{"v":0.751465173202633,"d":"0.75"},"down","no"]
["MSTRG.309","THEMIS2","ENST00000373921;ENST00000442118;ENST00000373927;ENST00000492877;ENST00000427466;ENST00000328928;ENST00000466068;ENST00000373925;ENST00000456990","GO:0005515(protein binding);GO:0002376(immune system process);GO:0006954(inflammatory response);GO:0007155(cell adhesion);GO:0050852(T cell receptor signaling pathway);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005737(cytoplasm)","NA","NA","NA","thymocyte selection associated family member 2 [Source:HGNC Symbol;Acc:HGNC:16839]",{"v":15.5485879971868,"d":"15.55"},{"v":36.6899496232417,"d":"36.69"},{"v":0.423783301881051,"d":"0.42"},{"v":-1.23860135183986,"d":"-1.24"},{"v":0.0675539935844297,"d":"0.07"},{"v":0.752400709346645,"d":"0.75"},"down","no"]
["ENSG00000213889","PPM1N","ENST00000396737;ENST00000451287;ENST00000396736;ENST00000456399;ENST00000401593;ENST00000415077;ENST00000396735","GO:0046872(metal ion binding);GO:0000287(magnesium ion binding);GO:0016787(hydrolase activity);GO:0003824(catalytic activity);GO:0006470(protein dephosphorylation);GO:0004721(phosphoprotein phosphatase activity);GO:0030145(manganese ion binding);GO:0004722(protein serine/threonine phosphatase activity);GO:0004722(protein serine/threonine phosphatase activity)","NA","NA","NA","protein phosphatase, Mg2+/Mn2+ dependent 1N (putative) [Source:HGNC Symbol;Acc:HGNC:26845]",{"v":0.647878714896927,"d":"0.65"},{"v":0.26991063243874,"d":"0.27"},{"v":2.40034528852424,"d":"2.40"},{"v":1.26324195175498,"d":"1.26"},{"v":0.067610107900702,"d":"0.07"},{"v":0.752400709346645,"d":"0.75"},"up","no"]
["MSTRG.11373","KLHL6","ENST00000341319;ENST00000489245;ENST00000487643","GO:0005515(protein binding);GO:0005634(nucleus);GO:0050853(B cell receptor signaling pathway);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0005737(cytoplasm);GO:0002467(germinal center formation);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0045893(positive regulation of transcription, DNA-templated);GO:0000976(transcription regulatory region sequence-specific DNA binding);GO:0000976(transcription regulatory region sequence-specific DNA binding)","NA","NA","NA","kelch like family member 6 [Source:HGNC Symbol;Acc:HGNC:18653]",{"v":1.1927583478096,"d":"1.19"},{"v":2.82214489408306,"d":"2.82"},{"v":0.422642490933173,"d":"0.42"},{"v":-1.24249027703014,"d":"-1.24"},{"v":0.0676673283692424,"d":"0.07"},{"v":0.752400709346645,"d":"0.75"},"down","no"]
["MSTRG.10413","APOL2","ENST00000489186;ENST00000249066;ENST00000451256;ENST00000529194;ENST00000454728;ENST00000358502;ENST00000473549","GO:0006810(transport);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005576(extracellular region);GO:0006629(lipid metabolic process);GO:0005789(endoplasmic reticulum membrane);GO:0042157(lipoprotein metabolic process);GO:0006869(lipid transport);GO:0008289(lipid binding);GO:0007275(multicellular organism development);GO:0008203(cholesterol metabolic process);GO:0005102(receptor binding);GO:0006953(acute-phase response);GO:0060135(maternal process involved in female pregnancy);GO:0008035(high-density lipoprotein particle binding);GO:0008035(high-density lipoprotein particle binding)","NA","NA","NA","apolipoprotein L2 [Source:HGNC Symbol;Acc:HGNC:619]",{"v":4.94235700660161,"d":"4.94"},{"v":11.6811275984501,"d":"11.68"},{"v":0.423106156913942,"d":"0.42"},{"v":-1.24090841537466,"d":"-1.24"},{"v":0.067842544132066,"d":"0.07"},{"v":0.753653059444962,"d":"0.75"},"down","no"]
["MSTRG.8412","LILRB3","ENST00000469273;ENST00000436504;ENST00000346401;ENST00000245620;ENST00000468668;ENST00000445347;ENST00000414379;ENST00000460208;ENST00000391750","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005886(plasma membrane);GO:0002376(immune system process);GO:0002250(adaptive immune response);GO:0005515(protein binding);GO:0005887(integral component of plasma membrane);GO:0043312(neutrophil degranulation);GO:0004872(receptor activity);GO:0045671(negative regulation of osteoclast differentiation);GO:0007166(cell surface receptor signaling pathway);GO:0030667(secretory granule membrane);GO:0004888(transmembrane signaling receptor activity);GO:0006952(defense response);GO:0006952(defense response)","04662(B cell receptor signaling pathway);04380(Osteoclast differentiation);04380(Osteoclast differentiation)","K06512","NA","leukocyte immunoglobulin like receptor B3 [Source:HGNC Symbol;Acc:HGNC:6607]",{"v":5.73836782949679,"d":"5.74"},{"v":13.5418181961991,"d":"13.54"},{"v":0.423751651835603,"d":"0.42"},{"v":-1.23870910282626,"d":"-1.24"},{"v":0.0682884045014151,"d":"0.07"},{"v":0.757906882033217,"d":"0.76"},"down","no"]
["ENSG00000188199","NUTM2B","ENST00000372321;ENST00000429828;ENST00000342531","NA","NA","NA","NA","NUT family member 2B [Source:HGNC Symbol;Acc:HGNC:23445]",{"v":0.318104316929134,"d":"0.32"},{"v":0.131646138976378,"d":"0.13"},{"v":2.41635887996847,"d":"2.42"},{"v":1.27283474104552,"d":"1.27"},{"v":0.0684456361646888,"d":"0.07"},{"v":0.758952440787461,"d":"0.76"},"up","no"]
["MSTRG.4420","PELI2","ENST00000267460;ENST00000559044;ENST00000561019","GO:0008063(Toll signaling pathway);GO:0016740(transferase activity);GO:0016567(protein ubiquitination);GO:0006468(protein phosphorylation);GO:0005515(protein binding);GO:0006955(immune response);GO:0061630(ubiquitin protein ligase activity);GO:0005829(cytosol);GO:0000209(protein polyubiquitination);GO:0004674(protein serine/threonine kinase activity);GO:0043123(positive regulation of I-kappaB kinase/NF-kappaB signaling);GO:0043410(positive regulation of MAPK cascade);GO:0001934(positive regulation of protein phosphorylation);GO:0034450(ubiquitin-ubiquitin ligase activity);GO:0034450(ubiquitin-ubiquitin ligase activity)","NA","NA","NA","pellino E3 ubiquitin protein ligase family member 2 [Source:HGNC Symbol;Acc:HGNC:8828]",{"v":3.02570249378783,"d":"3.03"},{"v":7.12733269241797,"d":"7.13"},{"v":0.424521012889796,"d":"0.42"},{"v":-1.23609212899687,"d":"-1.24"},{"v":0.0688719208013436,"d":"0.07"},{"v":0.762384892029017,"d":"0.76"},"down","no"]
["MSTRG.13276","ARG1","ENST00000368087;ENST00000498260;ENST00000275196;ENST00000484820;ENST00000356962;ENST00000469293","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0016787(hydrolase activity);GO:0016813(hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines);GO:0004053(arginase activity);GO:0000050(urea cycle);GO:0006525(arginine metabolic process);GO:0005576(extracellular region);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0043312(neutrophil degranulation);GO:0035580(specific granule lumen);GO:0035578(azurophil granule lumen);GO:0006527(arginine catabolic process);GO:0030145(manganese ion binding);GO:0001889(liver development);GO:0001938(positive regulation of endothelial cell proliferation);GO:0007565(female pregnancy);GO:0007568(aging);GO:0009611(response to wounding);GO:0009635(response to herbicide);GO:0010042(response to manganese ion);GO:0010043(response to zinc ion);GO:0010269(response to selenium ion);GO:0010963(regulation of L-arginine import);GO:0014075(response to amine);GO:0019547(arginine catabolic process to ornithine);GO:0030324(lung development);GO:0032496(response to lipopolysaccharide);GO:0032964(collagen biosynthetic process);GO:0033189(response to vitamin A);GO:0033197(response to vitamin E);GO:0042493(response to drug);GO:0043200(response to amino acid);GO:0043434(response to peptide hormone);GO:0046686(response to cadmium ion);GO:0048545(response to steroid hormone);GO:0048678(response to axon injury);GO:0051597(response to methylmercury);GO:0060056(mammary gland involution);GO:0060135(maternal process involved in female pregnancy);GO:0070207(protein homotrimerization);GO:0070301(cellular response to hydrogen peroxide);GO:0071222(cellular response to lipopolysaccharide);GO:0071353(cellular response to interleukin-4);GO:0071377(cellular response to glucagon stimulus);GO:0071549(cellular response to dexamethasone stimulus);GO:0071560(cellular response to transforming growth factor beta stimulus);GO:0005615(extracellular space);GO:0005741(mitochondrial outer membrane);GO:0043005(neuron projection);GO:0043025(neuronal cell body);GO:0043025(neuronal cell body)","00220(Arginine biosynthesis);00330(Arginine and proline metabolism);05146(Amoebiasis);05146(Amoebiasis)","K01476","EC:3.5.3.1","arginase 1 [Source:HGNC Symbol;Acc:HGNC:663]",{"v":1.81061271755725,"d":"1.81"},{"v":4.30684591450382,"d":"4.31"},{"v":0.420403412032874,"d":"0.42"},{"v":-1.25015371649372,"d":"-1.25"},{"v":0.0689797398784411,"d":"0.07"},{"v":0.762384892029017,"d":"0.76"},"down","no"]
["MSTRG.9802","SULF2","ENST00000484875;MSTRG.9802.1;ENST00000474450;ENST00000467815;ENST00000359930;ENST00000463221;ENST00000495544;ENST00000479472;ENST00000479970;ENST00000433632;ENST00000478766;ENST00000465769;ENST00000437955","GO:0040037(negative regulation of fibroblast growth factor receptor signaling pathway);GO:0046872(metal ion binding);GO:0016787(hydrolase activity);GO:0005509(calcium ion binding);GO:0003824(catalytic activity);GO:0005794(Golgi apparatus);GO:0008152(metabolic process);GO:0005783(endoplasmic reticulum);GO:0005886(plasma membrane);GO:0005615(extracellular space);GO:0008484(sulfuric ester hydrolase activity);GO:0009986(cell surface);GO:0008449(N-acetylglucosamine-6-sulfatase activity);GO:0005795(Golgi stack);GO:0051216(cartilage development);GO:0001822(kidney development);GO:0032836(glomerular basement membrane development);GO:0048706(embryonic skeletal system development);GO:0030177(positive regulation of Wnt signaling pathway);GO:0003094(glomerular filtration);GO:0010575(positive regulation of vascular endothelial growth factor production);GO:0004065(arylsulfatase activity);GO:0002063(chondrocyte development);GO:0009611(response to wounding);GO:0014846(esophagus smooth muscle contraction);GO:0030201(heparan sulfate proteoglycan metabolic process);GO:0035413(positive regulation of catenin import into nucleus);GO:0035860(glial cell-derived neurotrophic factor receptor signaling pathway);GO:0060348(bone development);GO:0060384(innervation);GO:0090263(positive regulation of canonical Wnt signaling pathway);GO:0097421(liver regeneration);GO:2000345(regulation of hepatocyte proliferation);GO:2000345(regulation of hepatocyte proliferation)","NA","NA","NA","sulfatase 2 [Source:HGNC Symbol;Acc:HGNC:20392]",{"v":11.3577297821487,"d":"11.36"},{"v":26.696352787662,"d":"26.70"},{"v":0.425441253061272,"d":"0.43"},{"v":-1.23296816337216,"d":"-1.23"},{"v":0.0689965340334663,"d":"0.07"},{"v":0.762384892029017,"d":"0.76"},"down","no"]
["ENSG00000113356","POLR3G","ENST00000503973;ENST00000399107;ENST00000505345;ENST00000512239;ENST00000514483;ENST00000504930","GO:0003899(DNA-directed 5'-3' RNA polymerase activity);GO:0006383(transcription from RNA polymerase III promoter);GO:0005634(nucleus);GO:0002376(immune system process);GO:0045087(innate immune response);GO:0051607(defense response to virus);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0008283(cell proliferation);GO:0032728(positive regulation of interferon-beta production);GO:0045089(positive regulation of innate immune response);GO:0032481(positive regulation of type I interferon production);GO:0005666(DNA-directed RNA polymerase III complex);GO:0000790(nuclear chromatin);GO:0006359(regulation of transcription from RNA polymerase III promoter);GO:0006359(regulation of transcription from RNA polymerase III promoter)","00230(Purine metabolism);00240(Pyrimidine metabolism);03020(RNA polymerase);04623(Cytosolic DNA-sensing pathway);05169(Epstein-Barr virus infection);05169(Epstein-Barr virus infection)","K03024","NA","RNA polymerase III subunit G [Source:HGNC Symbol;Acc:HGNC:30075]",{"v":0.405835220204031,"d":"0.41"},{"v":0.16740848420005,"d":"0.17"},{"v":2.42422134184708,"d":"2.42"},{"v":1.27752142909413,"d":"1.28"},{"v":0.0691561336628704,"d":"0.07"},{"v":0.762384892029017,"d":"0.76"},"up","no"]
["MSTRG.407","AGO4","ENST00000373210;ENST00000496257;ENST00000488778","GO:0005737(cytoplasm);GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0016020(membrane);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0030529(intracellular ribonucleoprotein complex);GO:0005515(protein binding);GO:0016604(nuclear body);GO:0031047(gene silencing by RNA);GO:0000932(P-body);GO:0006417(regulation of translation);GO:0038111(interleukin-7-mediated signaling pathway);GO:0048015(phosphatidylinositol-mediated signaling);GO:0045652(regulation of megakaryocyte differentiation);GO:0007223(Wnt signaling pathway, calcium modulating pathway);GO:0003725(double-stranded RNA binding);GO:0031054(pre-miRNA processing);GO:0035196(production of miRNAs involved in gene silencing by miRNA);GO:0070578(RISC-loading complex);GO:0006402(mRNA catabolic process);GO:0035278(miRNA mediated inhibition of translation);GO:0010501(RNA secondary structure unwinding);GO:0035280(miRNA loading onto RISC involved in gene silencing by miRNA);GO:0035194(posttranscriptional gene silencing by RNA);GO:0003727(single-stranded RNA binding);GO:0035198(miRNA binding);GO:0016442(RISC complex);GO:0007130(synaptonemal complex assembly);GO:0007140(male meiotic nuclear division);GO:0008584(male gonad development);GO:0010586(miRNA metabolic process);GO:0022604(regulation of cell morphogenesis);GO:0043066(negative regulation of apoptotic process);GO:0005634(nucleus);GO:0035068(micro-ribonucleoprotein complex);GO:0035068(micro-ribonucleoprotein complex)","NA","NA","NA","argonaute 4, RISC catalytic component [Source:HGNC Symbol;Acc:HGNC:18424]",{"v":5.34855098830329,"d":"5.35"},{"v":12.5647322699876,"d":"12.56"},{"v":0.42567966219853,"d":"0.43"},{"v":-1.23215993111548,"d":"-1.23"},{"v":0.0691582975013385,"d":"0.07"},{"v":0.762384892029017,"d":"0.76"},"down","no"]
["MSTRG.7075","CA4","ENST00000300900;ENST00000591725;ENST00000587265;ENST00000585705;ENST00000586876;ENST00000590203","GO:0016020(membrane);GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0016829(lyase activity);GO:0005886(plasma membrane);GO:0006730(one-carbon metabolic process);GO:0031225(anchored component of membrane);GO:0004089(carbonate dehydratase activity);GO:0070062(extracellular exosome);GO:0009986(cell surface);GO:0015701(bicarbonate transport);GO:0005515(protein binding);GO:0005791(rough endoplasmic reticulum);GO:0005793(endoplasmic reticulum-Golgi intermediate compartment);GO:0005794(Golgi apparatus);GO:0005802(trans-Golgi network);GO:0016324(apical plasma membrane);GO:0030658(transport vesicle membrane);GO:0030667(secretory granule membrane);GO:0031362(anchored component of external side of plasma membrane);GO:0031526(brush border membrane);GO:0046658(anchored component of plasma membrane);GO:0048471(perinuclear region of cytoplasm);GO:0016021(integral component of membrane);GO:0016021(integral component of membrane)","00910(Nitrogen metabolism);04964(Proximal tubule bicarbonate reclamation);04964(Proximal tubule bicarbonate reclamation)","K18246","EC:4.2.1.1","carbonic anhydrase 4 [Source:HGNC Symbol;Acc:HGNC:1375]",{"v":1.42892621369637,"d":"1.43"},{"v":3.43145262334984,"d":"3.43"},{"v":0.416420207574199,"d":"0.42"},{"v":-1.26388801505956,"d":"-1.26"},{"v":0.0692034968159069,"d":"0.07"},{"v":0.762384892029017,"d":"0.76"},"down","no"]
["MSTRG.1518","KLF6","ENST00000497571;ENST00000173785;ENST00000469435;ENST00000380946;ENST00000492125;ENST00000542957;ENST00000461124","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0043231(intracellular membrane-bounded organelle);GO:0046872(metal ion binding);GO:0005730(nucleolus);GO:0005829(cytosol);GO:0006366(transcription from RNA polymerase II promoter);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0001650(fibrillar center);GO:0005515(protein binding);GO:0045893(positive regulation of transcription, DNA-templated);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0001077(transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0030183(B cell differentiation);GO:0030183(B cell differentiation)","NA","NA","NA","Kruppel like factor 6 [Source:HGNC Symbol;Acc:HGNC:2235]",{"v":19.0194186880599,"d":"19.02"},{"v":44.6363733476136,"d":"44.64"},{"v":0.426096863648461,"d":"0.43"},{"v":-1.23074666251102,"d":"-1.23"},{"v":0.0692042124517804,"d":"0.07"},{"v":0.762384892029017,"d":"0.76"},"down","no"]
["MSTRG.5580","MEFV","ENST00000542898;ENST00000219596;ENST00000538326;ENST00000541159;ENST00000539154;ENST00000576315;ENST00000537682;ENST00000536980;ENST00000339854;ENST00000539145;ENST00000536379;ENST00000570511;ENST00000572244","GO:0050728(negative regulation of inflammatory response);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0005622(intracellular);GO:0003779(actin binding);GO:0005856(cytoskeleton);GO:0042995(cell projection);GO:0005515(protein binding);GO:0005874(microtubule);GO:0031410(cytoplasmic vesicle);GO:0002376(immune system process);GO:0045087(innate immune response);GO:0006954(inflammatory response);GO:0042802(identical protein binding);GO:0005829(cytosol);GO:0005875(microtubule associated complex);GO:0030027(lamellipodium);GO:0010508(positive regulation of autophagy);GO:0005776(autophagosome);GO:0001726(ruffle);GO:2001056(positive regulation of cysteine-type endopeptidase activity);GO:0034341(response to interferon-gamma);GO:0032691(negative regulation of interleukin-1 beta production);GO:0032695(negative regulation of interleukin-12 production);GO:0071641(negative regulation of macrophage inflammatory protein 1 alpha production);GO:1900016(negative regulation of cytokine production involved in inflammatory response);GO:1900226(negative regulation of NLRP3 inflammasome complex assembly);GO:1900226(negative regulation of NLRP3 inflammasome complex assembly)","04621(NOD-like receptor signaling pathway);04621(NOD-like receptor signaling pathway)","K12803","NA","MEFV, pyrin innate immunity regulator [Source:HGNC Symbol;Acc:HGNC:6998]",{"v":5.86952296493048,"d":"5.87"},{"v":13.7837582052293,"d":"13.78"},{"v":0.425828926881762,"d":"0.43"},{"v":-1.23165413840066,"d":"-1.23"},{"v":0.0693030233274737,"d":"0.07"},{"v":0.762384892029017,"d":"0.76"},"down","no"]
["MSTRG.8415","LILRA6","ENST00000430421;ENST00000396365;ENST00000245621;MSTRG.8415.1;ENST00000270464","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0002376(immune system process);GO:0002250(adaptive immune response);GO:0002250(adaptive immune response)","04380(Osteoclast differentiation);04380(Osteoclast differentiation)","K06512","NA","leukocyte immunoglobulin like receptor A6 [Source:HGNC Symbol;Acc:HGNC:15495]",{"v":18.7159701018881,"d":"18.72"},{"v":43.9225281938012,"d":"43.92"},{"v":0.426113224159294,"d":"0.43"},{"v":-1.23069126953179,"d":"-1.23"},{"v":0.0694111218610284,"d":"0.07"},{"v":0.762384892029017,"d":"0.76"},"down","no"]
["ENSG00000183765","CHEK2","ENST00000404276;ENST00000416671;ENST00000456369;ENST00000382580;ENST00000439200;ENST00000348295;ENST00000433728;ENST00000328354;ENST00000434810;ENST00000439346;ENST00000472807;ENST00000491919;ENST00000433028;ENST00000402731","GO:0004672(protein kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0005794(Golgi apparatus);GO:0005654(nucleoplasm);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0004674(protein serine/threonine kinase activity);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0051301(cell division);GO:0042803(protein homodimerization activity);GO:0005515(protein binding);GO:0006281(DNA repair);GO:0006974(cellular response to DNA damage stimulus);GO:0007049(cell cycle);GO:0006915(apoptotic process);GO:0045893(positive regulation of transcription, DNA-templated);GO:0042802(identical protein binding);GO:0006977(DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest);GO:0019901(protein kinase binding);GO:0050821(protein stabilization);GO:0044257(cellular protein catabolic process);GO:0031625(ubiquitin protein ligase binding);GO:0090307(mitotic spindle assembly);GO:0018105(peptidyl-serine phosphorylation);GO:1901796(regulation of signal transduction by p53 class mediator);GO:0042981(regulation of apoptotic process);GO:0016605(PML body);GO:0046777(protein autophosphorylation);GO:0090399(replicative senescence);GO:0000781(chromosome, telomeric region);GO:0000077(DNA damage checkpoint);GO:0006975(DNA damage induced protein phosphorylation);GO:0018107(peptidyl-threonine phosphorylation);GO:0000086(G2/M transition of mitotic cell cycle);GO:0006302(double-strand break repair);GO:0001302(replicative cell aging);GO:0008630(intrinsic apoptotic signaling pathway in response to DNA damage);GO:0042176(regulation of protein catabolic process);GO:0042770(signal transduction in response to DNA damage);GO:0072428(signal transduction involved in intra-S DNA damage checkpoint);GO:0001934(positive regulation of protein phosphorylation);GO:0006978(DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator);GO:0010332(response to gamma radiation);GO:0035690(cellular response to drug);GO:0042771(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator);GO:0071157(negative regulation of cell cycle arrest);GO:0071480(cellular response to gamma radiation);GO:1903416(response to glycoside);GO:1903926(cellular response to bisphenol A);GO:2000002(negative regulation of DNA damage checkpoint);GO:2000210(positive regulation of anoikis);GO:2000210(positive regulation of anoikis)","04110(Cell cycle);04115(p53 signaling pathway);04218(Cellular senescence);05166(HTLV-I infection);05166(HTLV-I infection)","K06641","EC:2.7.11.1","checkpoint kinase 2 [Source:HGNC Symbol;Acc:HGNC:16627]",{"v":0.240860159343312,"d":"0.24"},{"v":0.600346909705456,"d":"0.60"},{"v":0.401201631006119,"d":"0.40"},{"v":-1.31760062393314,"d":"-1.32"},{"v":0.0694125520070377,"d":"0.07"},{"v":0.762384892029017,"d":"0.76"},"down","no"]
["MSTRG.6620","ANKRD13B","ENST00000487527;ENST00000578943;ENST00000578811;ENST00000579719;ENST00000394859;ENST00000488766","GO:0016020(membrane);GO:0043231(intracellular membrane-bounded organelle);GO:0005886(plasma membrane);GO:0005737(cytoplasm);GO:0005768(endosome);GO:0005769(early endosome);GO:0005770(late endosome);GO:0005770(late endosome)","NA","NA","NA","ankyrin repeat domain 13B [Source:HGNC Symbol;Acc:HGNC:26363]",{"v":0.459502894736842,"d":"0.46"},{"v":0.194704494837572,"d":"0.19"},{"v":2.36000147361864,"d":"2.36"},{"v":1.23878776042679,"d":"1.24"},{"v":0.0694516049290676,"d":"0.07"},{"v":0.762384892029017,"d":"0.76"},"up","no"]
["MSTRG.2420","STX3","ENST00000529177;MSTRG.2420.3;ENST00000530498;ENST00000528805;ENST00000530221;ENST00000533637;ENST00000641815;ENST00000337979;ENST00000633708","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0006886(intracellular protein transport);GO:0016192(vesicle-mediated transport);GO:0006887(exocytosis);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0016081(synaptic vesicle docking);GO:0005484(SNAP receptor activity);GO:0030027(lamellipodium);GO:0070062(extracellular exosome);GO:0000149(SNARE binding);GO:0031201(SNARE complex);GO:0008284(positive regulation of cell proliferation);GO:0048278(vesicle docking);GO:0031629(synaptic vesicle fusion to presynaptic active zone membrane);GO:0042581(specific granule);GO:0042582(azurophil granule);GO:0045785(positive regulation of cell adhesion);GO:0005911(cell-cell junction);GO:0006836(neurotransmitter transport);GO:0008021(synaptic vesicle);GO:0050921(positive regulation of chemotaxis);GO:2000010(positive regulation of protein localization to cell surface);GO:0030426(growth cone);GO:0043005(neuron projection);GO:1903078(positive regulation of protein localization to plasma membrane);GO:0005773(vacuole);GO:0050544(arachidonic acid binding);GO:0006906(vesicle fusion);GO:0031175(neuron projection development);GO:0060291(long-term synaptic potentiation);GO:0061025(membrane fusion);GO:0098967(exocytic insertion of neurotransmitter receptor to postsynaptic membrane);GO:0016324(apical plasma membrane);GO:0030141(secretory granule);GO:0030425(dendrite);GO:0042470(melanosome);GO:0042589(zymogen granule membrane);GO:0042734(presynaptic membrane);GO:0097470(ribbon synapse);GO:0098794(postsynapse);GO:1990796(photoreceptor cell terminal bouton);GO:0005622(intracellular);GO:0098793(presynapse);GO:0098793(presynapse)","04130(SNARE interactions in vesicular transport);04721(Synaptic vesicle cycle);04721(Synaptic vesicle cycle)","K08486","NA","syntaxin 3 [Source:HGNC Symbol;Acc:HGNC:11438]",{"v":6.14809112675531,"d":"6.15"},{"v":14.4260475762396,"d":"14.43"},{"v":0.426179873195588,"d":"0.43"},{"v":-1.23046563298812,"d":"-1.23"},{"v":0.0695401081821765,"d":"0.07"},{"v":0.762661186456985,"d":"0.76"},"down","no"]
["MSTRG.564","ORC1","ENST00000371568","GO:0005634(nucleus);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0005730(nucleolus);GO:0005829(cytosol);GO:0003677(DNA binding);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0003682(chromatin binding);GO:0006260(DNA replication);GO:0005654(nucleoplasm);GO:0000784(nuclear chromosome, telomeric region);GO:0000082(G1/S transition of mitotic cell cycle);GO:0006270(DNA replication initiation);GO:0000808(origin recognition complex);GO:0005664(nuclear origin of replication recognition complex);GO:0000083(regulation of transcription involved in G1/S transition of mitotic cell cycle)","04110(Cell cycle)","K02603","NA","origin recognition complex subunit 1 [Source:HGNC Symbol;Acc:HGNC:8487]",{"v":0.552606,"d":"0.55"},{"v":0.227951,"d":"0.23"},{"v":2.42423152344144,"d":"2.42"},{"v":1.27752748832007,"d":"1.28"},{"v":0.0696425859241324,"d":"0.07"},{"v":0.763090099816562,"d":"0.76"},"up","no"]
["MSTRG.9755","OSER1-AS1","ENST00000439943;ENST00000435163;ENST00000442383;ENST00000623343;ENST00000437730","NA","NA","NA","NA","OSER1 antisense RNA 1 (head to head) [Source:HGNC Symbol;Acc:HGNC:48585]",{"v":0.797636844007319,"d":"0.80"},{"v":1.9172764231473,"d":"1.92"},{"v":0.416026001455732,"d":"0.42"},{"v":-1.2652543958504,"d":"-1.27"},{"v":0.0698381681186019,"d":"0.07"},{"v":0.763197244536133,"d":"0.76"},"down","no"]
["ENSG00000139714","MORN3","ENST00000355329;ENST00000392462;ENST00000542364","GO:0005634(nucleus);GO:0005515(protein binding);GO:0005515(protein binding)","NA","NA","NA","MORN repeat containing 3 [Source:HGNC Symbol;Acc:HGNC:29807]",{"v":1.07360764522822,"d":"1.07"},{"v":0.463927408195021,"d":"0.46"},{"v":2.31417162742174,"d":"2.31"},{"v":1.2104958639477,"d":"1.21"},{"v":0.0698381681186019,"d":"0.07"},{"v":0.763197244536133,"d":"0.76"},"up","no"]
["MSTRG.9820",null,"MSTRG.9820.1","NA","NA","NA","NA",null,{"v":2.227049,"d":"2.23"},{"v":5.260816,"d":"5.26"},{"v":0.42332767388177,"d":"0.42"},{"v":-1.24015329092989,"d":"-1.24"},{"v":0.0698424982128233,"d":"0.07"},{"v":0.763197244536133,"d":"0.76"},"down","no"]
["ENSG00000172264","MACROD2","ENST00000407045;ENST00000378058;ENST00000402914;ENST00000217246","GO:0005634(nucleus);GO:0005730(nucleolus);GO:0016787(hydrolase activity);GO:0005813(centrosome);GO:0016798(hydrolase activity, acting on glycosyl bonds);GO:0006974(cellular response to DNA damage stimulus);GO:0019213(deacetylase activity);GO:0007420(brain development);GO:0042278(purine nucleoside metabolic process);GO:0051725(protein de-ADP-ribosylation);GO:0051725(protein de-ADP-ribosylation)","NA","NA","NA","MACRO domain containing 2 [Source:HGNC Symbol;Acc:HGNC:16126]",{"v":0.0547071585860367,"d":"0.05"},{"v":0.141180139280677,"d":"0.14"},{"v":0.387498970214746,"d":"0.39"},{"v":-1.36773561848256,"d":"-1.37"},{"v":0.0700794067463966,"d":"0.07"},{"v":0.764658777774063,"d":"0.76"},"down","no"]
["ENSG00000152944","MED21","ENST00000282892;ENST00000546323;ENST00000536503;ENST00000544998;ENST00000536711;ENST00000621885","GO:0005634(nucleus);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0005515(protein binding);GO:0061630(ubiquitin protein ligase activity);GO:0001824(blastocyst development);GO:0016567(protein ubiquitination);GO:0019827(stem cell population maintenance);GO:0000151(ubiquitin ligase complex);GO:0016592(mediator complex);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0003899(DNA-directed 5'-3' RNA polymerase activity);GO:0003713(transcription coactivator activity);GO:0001104(RNA polymerase II transcription cofactor activity);GO:0001104(RNA polymerase II transcription cofactor activity)","NA","NA","NA","mediator complex subunit 21 [Source:HGNC Symbol;Acc:HGNC:11473]",{"v":0.885252898263027,"d":"0.89"},{"v":2.11220939826303,"d":"2.11"},{"v":0.419112280719427,"d":"0.42"},{"v":-1.25459129932329,"d":"-1.25"},{"v":0.0703129583059327,"d":"0.07"},{"v":0.764658777774063,"d":"0.76"},"down","no"]
["MSTRG.9449","GLB1L","ENST00000467548;ENST00000432839;ENST00000459951;ENST00000440853;ENST00000295759;ENST00000471516;ENST00000409640","GO:0016787(hydrolase activity);GO:0005975(carbohydrate metabolic process);GO:0008152(metabolic process);GO:0005576(extracellular region);GO:0004553(hydrolase activity, hydrolyzing O-glycosyl compounds);GO:0016798(hydrolase activity, acting on glycosyl bonds);GO:0004565(beta-galactosidase activity);GO:0005615(extracellular space);GO:0005773(vacuole);GO:0005773(vacuole)","NA","NA","NA","galactosidase beta 1 like [Source:HGNC Symbol;Acc:HGNC:28129]",{"v":0.426968826443858,"d":"0.43"},{"v":1.01793824391674,"d":"1.02"},{"v":0.419444724663259,"d":"0.42"},{"v":-1.2534473931817,"d":"-1.25"},{"v":0.0704163187153146,"d":"0.07"},{"v":0.764658777774063,"d":"0.76"},"down","no"]
["ENSG00000142731","PLK4","ENST00000270861;ENST00000513090;ENST00000503914;ENST00000507249;ENST00000510605;ENST00000507454","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0005829(cytosol);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0005813(centrosome);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0005730(nucleolus);GO:0007099(centriole replication);GO:0042802(identical protein binding);GO:0005814(centriole);GO:0060707(trophoblast giant cell differentiation);GO:0098535(de novo centriole assembly involved in multi-ciliated epithelial cell differentiation);GO:0098536(deuterosome);GO:0032154(cleavage furrow);GO:0000086(G2/M transition of mitotic cell cycle);GO:0010389(regulation of G2/M transition of mitotic cell cycle);GO:0097711(ciliary basal body docking);GO:0046601(positive regulation of centriole replication);GO:0001741(XY body);GO:0001741(XY body)","04068(FoxO signaling pathway);04068(FoxO signaling pathway)","K08863","EC:2.7.11.21","polo like kinase 4 [Source:HGNC Symbol;Acc:HGNC:11397]",{"v":0.357742615796519,"d":"0.36"},{"v":0.148059560017849,"d":"0.15"},{"v":2.41620747591977,"d":"2.42"},{"v":1.27274434192662,"d":"1.27"},{"v":0.0707924555536766,"d":"0.07"},{"v":0.764658777774063,"d":"0.76"},"up","no"]
["MSTRG.2523","EHD1","ENST00000320631;ENST00000455148;ENST00000457202;ENST00000488711;ENST00000359393;ENST00000421510;ENST00000466015;ENST00000621096;ENST00000498472;ENST00000433803;ENST00000411683;ENST00000484846","GO:0042632(cholesterol homeostasis);GO:0006810(transport);GO:0016020(membrane);GO:0015031(protein transport);GO:0005525(GTP binding);GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0005509(calcium ion binding);GO:0005886(plasma membrane);GO:0042995(cell projection);GO:0005515(protein binding);GO:0006886(intracellular protein transport);GO:0042802(identical protein binding);GO:0005768(endosome);GO:0060271(cilium assembly);GO:0005929(cilium);GO:0045296(cadherin binding);GO:0006897(endocytosis);GO:0070062(extracellular exosome);GO:0030030(cell projection organization);GO:0010008(endosome membrane);GO:0031901(early endosome membrane);GO:0055038(recycling endosome membrane);GO:0060170(ciliary membrane);GO:1901741(positive regulation of myoblast fusion);GO:0031175(neuron projection development);GO:0007596(blood coagulation);GO:0051260(protein homooligomerization);GO:0017137(Rab GTPase binding);GO:0005811(lipid particle);GO:0032456(endocytic recycling);GO:0020018(ciliary pocket membrane);GO:0034383(low-density lipoprotein particle clearance);GO:0010886(positive regulation of cholesterol storage);GO:1990090(cellular response to nerve growth factor stimulus);GO:2001137(positive regulation of endocytic recycling);GO:0061512(protein localization to cilium);GO:0031095(platelet dense tubular network membrane);GO:0016197(endosomal transport);GO:0005769(early endosome);GO:0030139(endocytic vesicle);GO:0043209(myelin sheath);GO:0048471(perinuclear region of cytoplasm);GO:0048471(perinuclear region of cytoplasm)","04144(Endocytosis);04144(Endocytosis)","K12483","NA","EH domain containing 1 [Source:HGNC Symbol;Acc:HGNC:3242]",{"v":10.5228527981974,"d":"10.52"},{"v":24.5794819477538,"d":"24.58"},{"v":0.42811532076082,"d":"0.43"},{"v":-1.22392862938254,"d":"-1.22"},{"v":0.0708001117511314,"d":"0.07"},{"v":0.764658777774063,"d":"0.76"},"down","no"]
["MSTRG.7444","ABHD3","MSTRG.7444.3;ENST00000580981;ENST00000577564;ENST00000584464;ENST00000577891;ENST00000577928;ENST00000578270;ENST00000579875;ENST00000289119;ENST00000580477;ENST00000579982","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016787(hydrolase activity);GO:0006629(lipid metabolic process);GO:0004623(phospholipase A2 activity);GO:0005886(plasma membrane);GO:0052689(carboxylic ester hydrolase activity);GO:0005575(cellular_component);GO:0046470(phosphatidylcholine metabolic process);GO:0008970(phosphatidylcholine 1-acylhydrolase activity);GO:0006656(phosphatidylcholine biosynthetic process);GO:0052739(phosphatidylserine 1-acylhydrolase activity);GO:0052740(1-acyl-2-lysophosphatidylserine acylhydrolase activity);GO:0052740(1-acyl-2-lysophosphatidylserine acylhydrolase activity)","NA","NA","NA","abhydrolase domain containing 3 [Source:HGNC Symbol;Acc:HGNC:18718]",{"v":2.07534628973889,"d":"2.08"},{"v":4.88713838662391,"d":"4.89"},{"v":0.424654700881626,"d":"0.42"},{"v":-1.23563787435603,"d":"-1.24"},{"v":0.0708173247339303,"d":"0.07"},{"v":0.764658777774063,"d":"0.76"},"down","no"]
["ENSG00000073536","NLE1","ENST00000588019;ENST00000588642;ENST00000589367;ENST00000586869;ENST00000442241","GO:0005634(nucleus);GO:0005730(nucleolus);GO:0007219(Notch signaling pathway);GO:0000027(ribosomal large subunit assembly);GO:0005840(ribosome);GO:0001756(somitogenesis);GO:0001822(kidney development);GO:0001826(inner cell mass cell differentiation);GO:0042273(ribosomal large subunit biogenesis);GO:0045930(negative regulation of mitotic cell cycle);GO:0048705(skeletal system morphogenesis);GO:0061484(hematopoietic stem cell homeostasis);GO:0090263(positive regulation of canonical Wnt signaling pathway);GO:2001268(negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway);GO:2001268(negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway)","NA","NA","NA","notchless homolog 1 [Source:HGNC Symbol;Acc:HGNC:19889]",{"v":1.11666944700714,"d":"1.12"},{"v":0.486977509610104,"d":"0.49"},{"v":2.29306164036445,"d":"2.29"},{"v":1.1972751368868,"d":"1.20"},{"v":0.070819396452212,"d":"0.07"},{"v":0.764658777774063,"d":"0.76"},"up","no"]
["ENSG00000171428","NAT1","ENST00000307719;ENST00000517574;ENST00000517492;ENST00000517441;ENST00000545197;ENST00000520546;ENST00000541942","GO:0005737(cytoplasm);GO:0016740(transferase activity);GO:0016746(transferase activity, transferring acyl groups);GO:0008152(metabolic process);GO:0005829(cytosol);GO:0016407(acetyltransferase activity);GO:0006805(xenobiotic metabolic process);GO:0004060(arylamine N-acetyltransferase activity);GO:0004060(arylamine N-acetyltransferase activity)","00232(Caffeine metabolism);00983(Drug metabolism - other enzymes);05204(Chemical carcinogenesis);05204(Chemical carcinogenesis)","K00622","EC:2.3.1.5","N-acetyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:7645]",{"v":0.59914962594697,"d":"0.60"},{"v":1.44749151325758,"d":"1.45"},{"v":0.413922721107071,"d":"0.41"},{"v":-1.27256665151653,"d":"-1.27"},{"v":0.0708621568256215,"d":"0.07"},{"v":0.764658777774063,"d":"0.76"},"down","no"]
["MSTRG.3077","LRRC23;RPL13P5;DSTNP2","ENST00000451681;ENST00000007969;ENST00000274820;ENST00000323702;ENST00000486401;ENST00000412023;ENST00000451612;ENST00000433346;ENST00000421824;ENST00000602547;ENST00000431207","GO:0003674(molecular_function);GO:0008150(biological_process);GO:0005575(cellular_component);GO:0005575(cellular_component)","NA","NA","NA","leucine rich repeat containing 23 [Source:HGNC Symbol;Acc:HGNC:19138];ribosomal protein L13 pseudogene 5 [Source:HGNC Symbol;Acc:HGNC:30363];destrin, actin depolymerizing factor pseudogene 2 [Source:HGNC Symbol;Acc:HGNC:34546]",{"v":0.628208991730878,"d":"0.63"},{"v":0.268034409321556,"d":"0.27"},{"v":2.34376247930626,"d":"2.34"},{"v":1.22882637211095,"d":"1.23"},{"v":0.0708858468508614,"d":"0.07"},{"v":0.764658777774063,"d":"0.76"},"up","no"]
["MSTRG.5564","AC141586.1","ENST00000399702;ENST00000567242","NA","NA","NA","NA",null,{"v":0.649621014176663,"d":"0.65"},{"v":0.277440117775354,"d":"0.28"},{"v":2.34148190025881,"d":"2.34"},{"v":1.22742188599436,"d":"1.23"},{"v":0.0709281618467656,"d":"0.07"},{"v":0.764658777774063,"d":"0.76"},"up","no"]
["MSTRG.15263","CFP;AL009172.2;SYN1","ENST00000247153;ENST00000640573;ENST00000396992;ENST00000480317;ENST00000485991;ENST00000638776;ENST00000469388;ENST00000295987;ENST00000478222;ENST00000377005","GO:0005576(extracellular region);GO:0002376(immune system process);GO:0045087(innate immune response);GO:0006956(complement activation);GO:0030449(regulation of complement activation);GO:0031012(extracellular matrix);GO:0043312(neutrophil degranulation);GO:0006955(immune response);GO:0005615(extracellular space);GO:0005788(endoplasmic reticulum lumen);GO:0035580(specific granule lumen);GO:1904724(tertiary granule lumen);GO:0042742(defense response to bacterium);GO:0006957(complement activation, alternative pathway);GO:0036066(protein O-linked fucosylation);GO:0005524(ATP binding);GO:0003824(catalytic activity);GO:0005794(Golgi apparatus);GO:0003779(actin binding);GO:0005515(protein binding);GO:0007269(neurotransmitter secretion);GO:0008021(synaptic vesicle);GO:0030054(cell junction);GO:0045202(synapse);GO:0005215(transporter activity);GO:0007268(chemical synaptic transmission);GO:0019901(protein kinase binding);GO:0048306(calcium-dependent protein binding);GO:0046928(regulation of neurotransmitter secretion);GO:0097091(synaptic vesicle clustering);GO:2000300(regulation of synaptic vesicle exocytosis);GO:0000795(synaptonemal complex);GO:0005829(cytosol);GO:0014069(postsynaptic density);GO:0030424(axon);GO:0030425(dendrite);GO:0030672(synaptic vesicle membrane);GO:0043195(terminal bouton);GO:0043209(myelin sheath);GO:0043229(intracellular organelle);GO:0048786(presynaptic active zone);GO:0098993(anchored component of synaptic vesicle membrane);GO:0036066(protein O-linked fucosylation)","05168(Herpes simplex infection);05168(Herpes simplex infection)","K15412","NA","complement factor properdin [Source:HGNC Symbol;Acc:HGNC:8864];synapsin I [Source:HGNC Symbol;Acc:HGNC:11494]",{"v":5.19875509946434,"d":"5.20"},{"v":12.1474764664426,"d":"12.15"},{"v":0.427969966752016,"d":"0.43"},{"v":-1.22441853736892,"d":"-1.22"},{"v":0.0709589671587898,"d":"0.07"},{"v":0.764658777774063,"d":"0.76"},"down","no"]
["MSTRG.10728","UBE2E1","ENST00000306627;ENST00000346855;ENST00000484048;ENST00000475680;ENST00000495141;ENST00000424381;ENST00000442670;ENST00000481622;ENST00000452012;ENST00000467766","GO:0005634(nucleus);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0016740(transferase activity);GO:0016567(protein ubiquitination);GO:0005515(protein binding);GO:0061631(ubiquitin conjugating enzyme activity);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0031145(anaphase-promoting complex-dependent catabolic process);GO:0043161(proteasome-mediated ubiquitin-dependent protein catabolic process);GO:0051437(positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition);GO:0051436(negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle);GO:0004842(ubiquitin-protein transferase activity);GO:0042787(protein ubiquitination involved in ubiquitin-dependent protein catabolic process);GO:0051439(regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle);GO:0070936(protein K48-linked ubiquitination);GO:0000151(ubiquitin ligase complex);GO:0006511(ubiquitin-dependent protein catabolic process);GO:0000209(protein polyubiquitination);GO:0010390(histone monoubiquitination);GO:0033523(histone H2B ubiquitination);GO:0032020(ISG15-protein conjugation);GO:0042296(ISG15 transferase activity);GO:0042296(ISG15 transferase activity)","04120(Ubiquitin mediated proteolysis);04120(Ubiquitin mediated proteolysis)","K20217","EC:2.3.2.23","ubiquitin conjugating enzyme E2 E1 [Source:HGNC Symbol;Acc:HGNC:12477]",{"v":2.41473073812622,"d":"2.41"},{"v":5.67418406701366,"d":"5.67"},{"v":0.425564400027844,"d":"0.43"},{"v":-1.23255062556011,"d":"-1.23"},{"v":0.0709792483784974,"d":"0.07"},{"v":0.764658777774063,"d":"0.76"},"down","no"]
["ENSG00000068650","ATP11A","ENST00000375645;ENST00000466946;ENST00000375630;ENST00000419631;ENST00000418678;ENST00000459011;ENST00000614170;ENST00000419448;ENST00000487903;ENST00000610419;ENST00000415301;ENST00000493489;ENST00000489577;ENST00000479193;ENST00000459908;ENST00000495930","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0043231(intracellular membrane-bounded organelle);GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0000287(magnesium ion binding);GO:0016787(hydrolase activity);GO:0005765(lysosomal membrane);GO:0005783(endoplasmic reticulum);GO:0005886(plasma membrane);GO:0006869(lipid transport);GO:0004012(phospholipid-translocating ATPase activity);GO:0015914(phospholipid transport);GO:0005515(protein binding);GO:0005768(endosome);GO:0005769(early endosome);GO:0055037(recycling endosome);GO:0043312(neutrophil degranulation);GO:0035579(specific granule membrane);GO:0070821(tertiary granule membrane);GO:0045332(phospholipid translocation);GO:0045332(phospholipid translocation)","NA","NA","NA","ATPase phospholipid transporting 11A [Source:HGNC Symbol;Acc:HGNC:13552]",{"v":1.38317872999345,"d":"1.38"},{"v":3.23937310012379,"d":"3.24"},{"v":0.426989632636201,"d":"0.43"},{"v":-1.22772705343953,"d":"-1.23"},{"v":0.0710367401970665,"d":"0.07"},{"v":0.764658777774063,"d":"0.76"},"down","no"]
["ENSG00000164951","PDP1","ENST00000297598;ENST00000518107;ENST00000396200;ENST00000517764;ENST00000518573;ENST00000520728;ENST00000521144;ENST00000520614;ENST00000518827","GO:0046872(metal ion binding);GO:0016787(hydrolase activity);GO:0003824(catalytic activity);GO:0006470(protein dephosphorylation);GO:0005739(mitochondrion);GO:0004721(phosphoprotein phosphatase activity);GO:0005515(protein binding);GO:0005759(mitochondrial matrix);GO:0004722(protein serine/threonine phosphatase activity);GO:0043169(cation binding);GO:0010510(regulation of acetyl-CoA biosynthetic process from pyruvate);GO:0035970(peptidyl-threonine dephosphorylation);GO:0004741([pyruvate dehydrogenase (lipoamide)] phosphatase activity);GO:0004741([pyruvate dehydrogenase (lipoamide)] phosphatase activity)","NA","NA","NA","pyruvate dehyrogenase phosphatase catalytic subunit 1 [Source:HGNC Symbol;Acc:HGNC:9279]",{"v":1.51203891772265,"d":"1.51"},{"v":3.54610240710334,"d":"3.55"},{"v":0.426394600080873,"d":"0.43"},{"v":-1.22973892716052,"d":"-1.23"},{"v":0.0710414779301298,"d":"0.07"},{"v":0.764658777774063,"d":"0.76"},"down","no"]
["MSTRG.2542","TIGD3","ENST00000309880","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0003677(DNA binding)","NA","NA","NA","tigger transposable element derived 3 [Source:HGNC Symbol;Acc:HGNC:18334]",{"v":2.026616,"d":"2.03"},{"v":4.789598,"d":"4.79"},{"v":0.423128621650502,"d":"0.42"},{"v":-1.2408318178042,"d":"-1.24"},{"v":0.0710852458447392,"d":"0.07"},{"v":0.764658777774063,"d":"0.76"},"down","no"]
["MSTRG.9821","UBE2V1;TMEM189-UBE2V1;TMEM189","ENST00000371674;ENST00000396059;ENST00000490555;ENST00000341698;ENST00000557021;ENST00000473860;ENST00000371652;ENST00000470565;ENST00000371658;ENST00000420027;ENST00000461960;ENST00000340309;ENST00000472923;ENST00000462217;ENST00000492371;ENST00000432266;ENST00000371656;ENST00000617119;ENST00000415862;ENST00000453505;ENST00000467839;ENST00000483534;ENST00000625172;ENST00000493090","GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0006355(regulation of transcription, DNA-templated);GO:0005515(protein binding);GO:0030154(cell differentiation);GO:0045893(positive regulation of transcription, DNA-templated);GO:0038095(Fc-epsilon receptor signaling pathway);GO:0031625(ubiquitin protein ligase binding);GO:0061630(ubiquitin protein ligase activity);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0002223(stimulatory C-type lectin receptor signaling pathway);GO:0050852(T cell receptor signaling pathway);GO:0043234(protein complex);GO:0006301(postreplication repair);GO:0070534(protein K63-linked ubiquitination);GO:0005737(cytoplasm);GO:0000151(ubiquitin ligase complex);GO:0007254(JNK cascade);GO:0043123(positive regulation of I-kappaB kinase/NF-kappaB signaling);GO:0051092(positive regulation of NF-kappaB transcription factor activity);GO:0070423(nucleotide-binding oligomerization domain containing signaling pathway);GO:0000187(activation of MAPK activity);GO:0006282(regulation of DNA repair);GO:0035370(UBC13-UEV1A complex);GO:0000209(protein polyubiquitination);GO:0031371(ubiquitin conjugating enzyme complex);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005783(endoplasmic reticulum);GO:0016567(protein ubiquitination);GO:0005789(endoplasmic reticulum membrane);GO:0031371(ubiquitin conjugating enzyme complex)","NA","NA","NA","ubiquitin conjugating enzyme E2 V1 [Source:HGNC Symbol;Acc:HGNC:12494];TMEM189-UBE2V1 readthrough [Source:HGNC Symbol;Acc:HGNC:33521];transmembrane protein 189 [Source:HGNC Symbol;Acc:HGNC:16735]",{"v":10.1039200329438,"d":"10.10"},{"v":4.48699483512432,"d":"4.49"},{"v":2.25182341505054,"d":"2.25"},{"v":1.17109369765815,"d":"1.17"},{"v":0.0710967327321765,"d":"0.07"},{"v":0.764658777774063,"d":"0.76"},"up","no"]
["MSTRG.13227","FAM26F","ENST00000368605;ENST00000368606;ENST00000368604","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0098655(cation transmembrane transport);GO:0006811(ion transport);GO:0005887(integral component of plasma membrane);GO:0034220(ion transmembrane transport);GO:0005261(cation channel activity);GO:0005261(cation channel activity)","NA","NA","NA","family with sequence similarity 26 member F [Source:HGNC Symbol;Acc:HGNC:33391]",{"v":3.37609134422111,"d":"3.38"},{"v":7.99106637939698,"d":"7.99"},{"v":0.422483206111958,"d":"0.42"},{"v":-1.24303410009736,"d":"-1.24"},{"v":0.0711398314278425,"d":"0.07"},{"v":0.764658777774063,"d":"0.76"},"down","no"]
["ENSG00000219481","NBPF1","ENST00000430580;ENST00000449853;ENST00000599908;ENST00000599069;ENST00000432949;ENST00000392963;ENST00000420513","GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0055114(oxidation-reduction process)","NA","NA","NA","NBPF member 1 [Source:HGNC Symbol;Acc:HGNC:26088]",{"v":1.05425107337046,"d":"1.05"},{"v":0.463723649525057,"d":"0.46"},{"v":2.27344685665745,"d":"2.27"},{"v":1.18488128051401,"d":"1.18"},{"v":0.0711696718670403,"d":"0.07"},{"v":0.764658777774063,"d":"0.76"},"up","no"]
["ENSG00000183458","AC138932.1","ENST00000534164;ENST00000537889","NA","NA","NA","NA",null,{"v":1.790173,"d":"1.79"},{"v":0.791052443923865,"d":"0.79"},{"v":2.26302695067875,"d":"2.26"},{"v":1.17825376594774,"d":"1.18"},{"v":0.0711857601623889,"d":"0.07"},{"v":0.764658777774063,"d":"0.76"},"up","no"]
["ENSG00000123472","ATPAF1","ENST00000576409;ENST00000371937;ENST00000460928;ENST00000525633;ENST00000574428;ENST00000534216;ENST00000474020;ENST00000526821;ENST00000492233;ENST00000329231;ENST00000542495","GO:0005739(mitochondrion);GO:0006461(protein complex assembly);GO:0005515(protein binding);GO:0033615(mitochondrial proton-transporting ATP synthase complex assembly);GO:0033615(mitochondrial proton-transporting ATP synthase complex assembly)","NA","NA","NA","ATP synthase mitochondrial F1 complex assembly factor 1 [Source:HGNC Symbol;Acc:HGNC:18803]",{"v":0.706581139686454,"d":"0.71"},{"v":1.68085281979919,"d":"1.68"},{"v":0.420370618630886,"d":"0.42"},{"v":-1.25026625773957,"d":"-1.25"},{"v":0.0712619607769419,"d":"0.07"},{"v":0.764658777774063,"d":"0.76"},"down","no"]
["ENSG00000168646","AXIN2","ENST00000578251;ENST00000618960;ENST00000307078;ENST00000375702;ENST00000580513;ENST00000585045","GO:0008285(negative regulation of cell proliferation);GO:0010718(positive regulation of epithelial to mesenchymal transition);GO:0001934(positive regulation of protein phosphorylation);GO:0090090(negative regulation of canonical Wnt signaling pathway);GO:0010942(positive regulation of cell death);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0043547(positive regulation of GTPase activity);GO:0005515(protein binding);GO:0007275(multicellular organism development);GO:0016055(Wnt signaling pathway);GO:0005096(GTPase activator activity);GO:0005886(plasma membrane);GO:0005829(cytosol);GO:0016579(protein deubiquitination);GO:0090263(positive regulation of canonical Wnt signaling pathway);GO:0031625(ubiquitin protein ligase binding);GO:0019899(enzyme binding);GO:1904837(beta-catenin-TCF complex assembly);GO:0005813(centrosome);GO:0008013(beta-catenin binding);GO:0030877(beta-catenin destruction complex);GO:0034613(cellular protein localization);GO:0035414(negative regulation of catenin import into nucleus);GO:0042476(odontogenesis);GO:0070602(regulation of centromeric sister chromatid cohesion);GO:0048255(mRNA stabilization);GO:0043570(maintenance of DNA repeat elements);GO:0070411(I-SMAD binding);GO:0001756(somitogenesis);GO:0001957(intramembranous ossification);GO:0003139(secondary heart field specification);GO:0003413(chondrocyte differentiation involved in endochondral bone morphogenesis);GO:0008283(cell proliferation);GO:0030111(regulation of Wnt signaling pathway);GO:0030282(bone mineralization);GO:0032423(regulation of mismatch repair);GO:0045668(negative regulation of osteoblast differentiation);GO:0061181(regulation of chondrocyte development);GO:0061181(regulation of chondrocyte development)","04310(Wnt signaling pathway);04390(Hippo signaling pathway);04550(Signaling pathways regulating pluripotency of stem cells);05200(Pathways in cancer);05210(Colorectal cancer);05225(Hepatocellular carcinoma);05226(Gastric cancer);05217(Basal cell carcinoma);05213(Endometrial cancer);05224(Breast cancer);05165(Human papillomavirus infection);05165(Human papillomavirus infection)","K04385","NA","axin 2 [Source:HGNC Symbol;Acc:HGNC:904]",{"v":1.74280509758898,"d":"1.74"},{"v":0.766678282051282,"d":"0.77"},{"v":2.27318960037061,"d":"2.27"},{"v":1.18471802032237,"d":"1.18"},{"v":0.0713097332204179,"d":"0.07"},{"v":0.764658777774063,"d":"0.76"},"up","no"]
["ENSG00000081985","IL12RB2","ENST00000262345;ENST00000541374;ENST00000371000;ENST00000465396;ENST00000441640","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0004896(cytokine receptor activity);GO:0005886(plasma membrane);GO:0005887(integral component of plasma membrane);GO:0035722(interleukin-12-mediated signaling pathway);GO:0032729(positive regulation of interferon-gamma production);GO:0007166(cell surface receptor signaling pathway);GO:0008284(positive regulation of cell proliferation);GO:0019901(protein kinase binding);GO:0018108(peptidyl-tyrosine phosphorylation);GO:0032496(response to lipopolysaccharide);GO:0032609(interferon-gamma production);GO:0034097(response to cytokine);GO:0009897(external side of plasma membrane);GO:0019221(cytokine-mediated signaling pathway);GO:0019221(cytokine-mediated signaling pathway)","04630(Jak-STAT signaling pathway);04060(Cytokine-cytokine receptor interaction);04658(Th1 and Th2 cell differentiation);05200(Pathways in cancer);05321(Inflammatiory bowel disease (IBD));05321(Inflammatiory bowel disease (IBD))","K05064","NA","interleukin 12 receptor subunit beta 2 [Source:HGNC Symbol;Acc:HGNC:5972]",{"v":1.24016799858257,"d":"1.24"},{"v":0.540246720529176,"d":"0.54"},{"v":2.29555858732065,"d":"2.30"},{"v":1.19884525302974,"d":"1.20"},{"v":0.07152536805775,"d":"0.07"},{"v":0.766288685188101,"d":"0.77"},"up","no"]
["MSTRG.4515","NUMB;AC004846.2","MSTRG.4515.4;ENST00000554546;ENST00000557597;ENST00000554014;ENST00000555394;ENST00000557577;ENST00000554818;ENST00000535282;ENST00000557581;ENST00000557486;ENST00000554521;ENST00000559312;ENST00000556112;ENST00000557774;ENST00000556772;ENST00000553415;ENST00000555859;ENST00000555307;MSTRG.4515.2;ENST00000556600;MSTRG.4515.3;ENST00000560335;ENST00000556578;ENST00000356296;ENST00000556989;ENST00000555238;ENST00000555738;ENST00000553997;ENST00000554315;ENST00000556700;MSTRG.4515.5;ENST00000359560;ENST00000355058;ENST00000557031;ENST00000554394","GO:0016020(membrane);GO:0005515(protein binding);GO:0007275(multicellular organism development);GO:0007399(nervous system development);GO:0005925(focal adhesion);GO:0005886(plasma membrane);GO:0045296(cadherin binding);GO:0030335(positive regulation of cell migration);GO:0030136(clathrin-coated vesicle);GO:0050769(positive regulation of neurogenesis);GO:1903077(negative regulation of protein localization to plasma membrane);GO:0021670(lateral ventricle development);GO:0021849(neuroblast division in subventricular zone);GO:0008013(beta-catenin binding);GO:0045294(alpha-catenin binding);GO:0007405(neuroblast proliferation);GO:0007409(axonogenesis);GO:0030862(positive regulation of polarized epithelial cell differentiation);GO:0030900(forebrain development);GO:0034332(adherens junction organization);GO:0045746(negative regulation of Notch signaling pathway);GO:0060487(lung epithelial cell differentiation);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005769(early endosome);GO:0016323(basolateral plasma membrane);GO:0019897(extrinsic component of plasma membrane);GO:0031410(cytoplasmic vesicle);GO:0045177(apical part of cell);GO:0045177(apical part of cell)","04330(Notch signaling pathway);04330(Notch signaling pathway)","K06057","NA","NUMB, endocytic adaptor protein [Source:HGNC Symbol;Acc:HGNC:8060]",{"v":7.62146953947049,"d":"7.62"},{"v":17.7645305966319,"d":"17.76"},{"v":0.42902735301745,"d":"0.43"},{"v":-1.22085846393496,"d":"-1.22"},{"v":0.0717210439160917,"d":"0.07"},{"v":0.767092121349023,"d":"0.77"},"down","no"]
["MSTRG.2543","FRMD8","ENST00000317568;ENST00000416776;ENST00000531151;ENST00000528854;ENST00000355991;ENST00000526201;ENST00000525156;ENST00000531296","GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0005515(protein binding)","NA","NA","NA","FERM domain containing 8 [Source:HGNC Symbol;Acc:HGNC:25462]",{"v":4.04010575629431,"d":"4.04"},{"v":9.43618041652408,"d":"9.44"},{"v":0.428150541634358,"d":"0.43"},{"v":-1.22380994432956,"d":"-1.22"},{"v":0.0717738100899721,"d":"0.07"},{"v":0.767092121349023,"d":"0.77"},"down","no"]
["MSTRG.238","LYPLA2","ENST00000374514;ENST00000374503;ENST00000492577;ENST00000472213;ENST00000374501;ENST00000374502;ENST00000421070;ENST00000420982","GO:0005737(cytoplasm);GO:0016787(hydrolase activity);GO:0006629(lipid metabolic process);GO:0006631(fatty acid metabolic process);GO:0005829(cytosol);GO:0045296(cadherin binding);GO:0070062(extracellular exosome);GO:0007411(axon guidance);GO:0052689(carboxylic ester hydrolase activity);GO:0008474(palmitoyl-(protein) hydrolase activity);GO:0002084(protein depalmitoylation);GO:0002084(protein depalmitoylation)","00564(Glycerophospholipid metabolism);00564(Glycerophospholipid metabolism)","K06130","EC:3.1.1.5","lysophospholipase II [Source:HGNC Symbol;Acc:HGNC:6738]",{"v":6.35534970582878,"d":"6.36"},{"v":14.8569551470856,"d":"14.86"},{"v":0.427769327086881,"d":"0.43"},{"v":-1.22509505615749,"d":"-1.23"},{"v":0.0717914649360862,"d":"0.07"},{"v":0.767092121349023,"d":"0.77"},"down","no"]
["ENSG00000006555","TTC22","ENST00000371276;ENST00000371274;ENST00000488771;ENST00000474654;ENST00000448308","NA","NA","NA","NA","tetratricopeptide repeat domain 22 [Source:HGNC Symbol;Acc:HGNC:26067]",{"v":0.811509349628406,"d":"0.81"},{"v":0.352921995540875,"d":"0.35"},{"v":2.29940145381054,"d":"2.30"},{"v":1.20125836899624,"d":"1.20"},{"v":0.0719697838428529,"d":"0.07"},{"v":0.768215069280956,"d":"0.77"},"up","no"]
["ENSG00000205189","ZBTB10","ENST00000455036;ENST00000430430;ENST00000426744","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0005654(nucleoplasm);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0005515(protein binding)","NA","NA","NA","zinc finger and BTB domain containing 10 [Source:HGNC Symbol;Acc:HGNC:30953]",{"v":0.727378945184025,"d":"0.73"},{"v":0.319706453014879,"d":"0.32"},{"v":2.27514627347911,"d":"2.28"},{"v":1.18595930189994,"d":"1.19"},{"v":0.0720523427847582,"d":"0.07"},{"v":0.768215069280956,"d":"0.77"},"up","no"]
["ENSG00000152894","PTPRK","ENST00000368226;ENST00000434424;ENST00000532331;ENST00000368215;ENST00000368205;ENST00000495748;ENST00000525459","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0043231(intracellular membrane-bounded organelle);GO:0016787(hydrolase activity);GO:0007155(cell adhesion);GO:0005886(plasma membrane);GO:0004725(protein tyrosine phosphatase activity);GO:0016791(phosphatase activity);GO:0006470(protein dephosphorylation);GO:0016311(dephosphorylation);GO:0035335(peptidyl-tyrosine dephosphorylation);GO:0030054(cell junction);GO:0004721(phosphoprotein phosphatase activity);GO:0005515(protein binding);GO:0007165(signal transduction);GO:0005887(integral component of plasma membrane);GO:0019901(protein kinase binding);GO:0008285(negative regulation of cell proliferation);GO:0005912(adherens junction);GO:0009986(cell surface);GO:0048041(focal adhesion assembly);GO:0045786(negative regulation of cell cycle);GO:0045892(negative regulation of transcription, DNA-templated);GO:0016477(cell migration);GO:0007179(transforming growth factor beta receptor signaling pathway);GO:0005911(cell-cell junction);GO:0034394(protein localization to cell surface);GO:0008013(beta-catenin binding);GO:0045295(gamma-catenin binding);GO:0030336(negative regulation of cell migration);GO:0034644(cellular response to UV);GO:0034614(cellular response to reactive oxygen species);GO:0010839(negative regulation of keratinocyte proliferation);GO:0005001(transmembrane receptor protein tyrosine phosphatase activity);GO:0031256(leading edge membrane);GO:0031175(neuron projection development);GO:0001750(photoreceptor outer segment);GO:0030424(axon);GO:0030425(dendrite);GO:0043025(neuronal cell body);GO:0043025(neuronal cell body)","NA","NA","NA","protein tyrosine phosphatase, receptor type K [Source:HGNC Symbol;Acc:HGNC:9674]",{"v":0.310250032222222,"d":"0.31"},{"v":0.133026547,"d":"0.13"},{"v":2.33224149028105,"d":"2.33"},{"v":1.22171717910145,"d":"1.22"},{"v":0.0720879445513603,"d":"0.07"},{"v":0.768215069280956,"d":"0.77"},"up","no"]
["MSTRG.14445","TMEM55A","ENST00000518869;ENST00000285419;ENST00000520709;ENST00000520014;ENST00000518359","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016787(hydrolase activity);GO:0005765(lysosomal membrane);GO:0005764(lysosome);GO:0046856(phosphatidylinositol dephosphorylation);GO:0005768(endosome);GO:0031902(late endosome membrane);GO:0034597(phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity);GO:0034597(phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity)","04070(Phosphatidylinositol signaling system);04070(Phosphatidylinositol signaling system)","K13084","EC:3.1.3.78","transmembrane protein 55A [Source:HGNC Symbol;Acc:HGNC:25452]",{"v":5.97893950880626,"d":"5.98"},{"v":13.946671037182,"d":"13.95"},{"v":0.428700117244203,"d":"0.43"},{"v":-1.22195928317309,"d":"-1.22"},{"v":0.0722876099615346,"d":"0.07"},{"v":0.769484645351133,"d":"0.77"},"down","no"]
["ENSG00000082438","COBLL1","ENST00000375458;ENST00000409184;ENST00000496396;ENST00000474975;ENST00000493868;ENST00000392717;ENST00000456171;ENST00000629362;ENST00000493921;ENST00000452626;ENST00000460238","GO:0003779(actin binding);GO:0045296(cadherin binding);GO:0070062(extracellular exosome);GO:0003785(actin monomer binding);GO:0030041(actin filament polymerization);GO:0051639(actin filament network formation);GO:0051639(actin filament network formation)","NA","NA","NA","cordon-bleu WH2 repeat protein like 1 [Source:HGNC Symbol;Acc:HGNC:23571]",{"v":0.373013411514728,"d":"0.37"},{"v":0.163293890441262,"d":"0.16"},{"v":2.28430721141342,"d":"2.28"},{"v":1.19175668860705,"d":"1.19"},{"v":0.0723665069547275,"d":"0.07"},{"v":0.769484645351133,"d":"0.77"},"up","no"]
["ENSG00000145284","SCD5","ENST00000319540","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0046872(metal ion binding);GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0006629(lipid metabolic process);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0006631(fatty acid metabolic process);GO:0006633(fatty acid biosynthetic process);GO:0006636(unsaturated fatty acid biosynthetic process);GO:0004768(stearoyl-CoA 9-desaturase activity);GO:0016717(oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water);GO:0046949(fatty-acyl-CoA biosynthetic process);GO:1903966(monounsaturated fatty acid biosynthetic process)","01040(Biosynthesis of unsaturated fatty acids);04152(AMPK signaling pathway);03320(PPAR signaling pathway)","K00507","EC:1.14.19.1","stearoyl-CoA desaturase 5 [Source:HGNC Symbol;Acc:HGNC:21088]",{"v":0.167977095060578,"d":"0.17"},{"v":0.415667663793103,"d":"0.42"},{"v":0.404113934501742,"d":"0.40"},{"v":-1.30716599605107,"d":"-1.31"},{"v":0.0724837570487918,"d":"0.07"},{"v":0.769484645351133,"d":"0.77"},"down","no"]
["MSTRG.12120","HMGCR","ENST00000343975;ENST00000287936;ENST00000515776;ENST00000511206;ENST00000442032;ENST00000507942;ENST00000512053;ENST00000504466;ENST00000514315;ENST00000508070","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016491(oxidoreductase activity);GO:0050661(NADP binding);GO:0055114(oxidation-reduction process);GO:0006629(lipid metabolic process);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0006694(steroid biosynthetic process);GO:0008202(steroid metabolic process);GO:0008299(isoprenoid biosynthetic process);GO:0016126(sterol biosynthetic process);GO:0016616(oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor);GO:0005515(protein binding);GO:0008203(cholesterol metabolic process);GO:0004420(hydroxymethylglutaryl-CoA reductase (NADPH) activity);GO:0050662(coenzyme binding);GO:0015936(coenzyme A metabolic process);GO:0005778(peroxisomal membrane);GO:0006695(cholesterol biosynthetic process);GO:0045540(regulation of cholesterol biosynthetic process);GO:0019216(regulation of lipid metabolic process);GO:0051262(protein tetramerization);GO:0070402(NADPH binding);GO:0042282(hydroxymethylglutaryl-CoA reductase activity);GO:0042803(protein homodimerization activity);GO:0051721(protein phosphatase 2A binding);GO:0006743(ubiquinone metabolic process);GO:0007568(aging);GO:0007584(response to nutrient);GO:0008284(positive regulation of cell proliferation);GO:0008542(visual learning);GO:0010664(negative regulation of striated muscle cell apoptotic process);GO:0010666(positive regulation of cardiac muscle cell apoptotic process);GO:0032874(positive regulation of stress-activated MAPK cascade);GO:0043066(negative regulation of apoptotic process);GO:0043407(negative regulation of MAP kinase activity);GO:0045445(myoblast differentiation);GO:0045471(response to ethanol);GO:0048643(positive regulation of skeletal muscle tissue development);GO:0048661(positive regulation of smooth muscle cell proliferation);GO:0061045(negative regulation of wound healing);GO:0061179(negative regulation of insulin secretion involved in cellular response to glucose stimulus);GO:0070374(positive regulation of ERK1 and ERK2 cascade);GO:0097756(negative regulation of blood vessel diameter);GO:0043231(intracellular membrane-bounded organelle);GO:0043231(intracellular membrane-bounded organelle)","00900(Terpenoid backbone biosynthesis);04152(AMPK signaling pathway);04976(Bile secretion);04976(Bile secretion)","K00021","EC:1.1.1.34","3-hydroxy-3-methylglutaryl-CoA reductase [Source:HGNC Symbol;Acc:HGNC:5006]",{"v":3.20365254304103,"d":"3.20"},{"v":7.45809185583266,"d":"7.46"},{"v":0.429553913382763,"d":"0.43"},{"v":-1.21908887926607,"d":"-1.22"},{"v":0.0726233530268234,"d":"0.07"},{"v":0.769484645351133,"d":"0.77"},"down","no"]
["MSTRG.14460","CPQ","ENST00000220763;ENST00000519900;ENST00000525310;ENST00000529551;ENST00000521142;ENST00000519484;ENST00000517742;ENST00000522617;ENST00000532528","GO:0005615(extracellular space);GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0016787(hydrolase activity);GO:0005794(Golgi apparatus);GO:0005783(endoplasmic reticulum);GO:0042803(protein homodimerization activity);GO:0008233(peptidase activity);GO:0006508(proteolysis);GO:0005576(extracellular region);GO:0004180(carboxypeptidase activity);GO:0008237(metallopeptidase activity);GO:0006590(thyroid hormone generation);GO:0042246(tissue regeneration);GO:0005764(lysosome);GO:0070062(extracellular exosome);GO:0043171(peptide catabolic process);GO:0070573(metallodipeptidase activity);GO:0070573(metallodipeptidase activity)","NA","NA","NA","carboxypeptidase Q [Source:HGNC Symbol;Acc:HGNC:16910]",{"v":4.11689046977148,"d":"4.12"},{"v":9.60492006479607,"d":"9.60"},{"v":0.428623085043747,"d":"0.43"},{"v":-1.22221854123024,"d":"-1.22"},{"v":0.0726321809148924,"d":"0.07"},{"v":0.769484645351133,"d":"0.77"},"down","no"]
["MSTRG.65","NADK","ENST00000341991;ENST00000497747;ENST00000341426;ENST00000492845;MSTRG.65.2;ENST00000480542;ENST00000464373;ENST00000489538;ENST00000460602;ENST00000378625;ENST00000342348;ENST00000477235;ENST00000492768;ENST00000498806;MSTRG.65.3;ENST00000497615;ENST00000469045;MSTRG.65.1;MSTRG.65.7;ENST00000480499","GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0008152(metabolic process);GO:0003951(NAD+ kinase activity);GO:0005829(cytosol);GO:0019674(NAD metabolic process);GO:0006741(NADP biosynthetic process);GO:0005515(protein binding);GO:0046034(ATP metabolic process);GO:0046034(ATP metabolic process)","00760(Nicotinate and nicotinamide metabolism);00760(Nicotinate and nicotinamide metabolism)","K00858","EC:2.7.1.23","NAD kinase [Source:HGNC Symbol;Acc:HGNC:29831]",{"v":15.955452777855,"d":"15.96"},{"v":37.0825710710933,"d":"37.08"},{"v":0.430268245081114,"d":"0.43"},{"v":-1.21669172532972,"d":"-1.22"},{"v":0.0726499483237922,"d":"0.07"},{"v":0.769484645351133,"d":"0.77"},"down","no"]
["MSTRG.4038","DNAJC3-AS1","ENST00000499499","NA","NA","NA","NA","DNAJC3 antisense RNA 1 (head to head) [Source:HGNC Symbol;Acc:HGNC:39808]",{"v":0.380534503654485,"d":"0.38"},{"v":0.926725497674418,"d":"0.93"},{"v":0.410622675872652,"d":"0.41"},{"v":-1.28411479509377,"d":"-1.28"},{"v":0.072710213278198,"d":"0.07"},{"v":0.769484645351133,"d":"0.77"},"down","no"]
["ENSG00000129680","MAP7D3","ENST00000316077;ENST00000370660;ENST00000495432;ENST00000489788;ENST00000370661","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005856(cytoskeleton);GO:0000226(microtubule cytoskeleton organization);GO:0008017(microtubule binding);GO:0005819(spindle);GO:0015630(microtubule cytoskeleton);GO:0005198(structural molecule activity);GO:0015631(tubulin binding);GO:0046785(microtubule polymerization);GO:0046785(microtubule polymerization)","NA","NA","NA","MAP7 domain containing 3 [Source:HGNC Symbol;Acc:HGNC:25742]",{"v":1.07979173439932,"d":"1.08"},{"v":0.475400494269138,"d":"0.48"},{"v":2.2713306936278,"d":"2.27"},{"v":1.18353777003613,"d":"1.18"},{"v":0.0727182798878583,"d":"0.07"},{"v":0.769484645351133,"d":"0.77"},"up","no"]
["MSTRG.12522","NUDCD2","ENST00000302764;ENST00000521797;ENST00000517501;ENST00000519395","GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005694(chromosome);GO:0015630(microtubule cytoskeleton);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0000922(spindle pole);GO:0005815(microtubule organizing center);GO:0000775(chromosome, centromeric region);GO:0000776(kinetochore);GO:0000777(condensed chromosome kinetochore);GO:0070062(extracellular exosome);GO:0006457(protein folding);GO:0005622(intracellular);GO:0051082(unfolded protein binding);GO:0032502(developmental process);GO:0032502(developmental process)","NA","NA","NA","NudC domain containing 2 [Source:HGNC Symbol;Acc:HGNC:30535]",{"v":0.275243380807053,"d":"0.28"},{"v":0.653756117667006,"d":"0.65"},{"v":0.421018440009841,"d":"0.42"},{"v":-1.24804467221766,"d":"-1.25"},{"v":0.0728443936950321,"d":"0.07"},{"v":0.770142395852131,"d":"0.77"},"down","no"]
["ENSG00000111490","TBC1D30","ENST00000542120;ENST00000544190;ENST00000456757","GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0016020(membrane);GO:0005096(GTPase activator activity);GO:0006886(intracellular protein transport);GO:0031338(regulation of vesicle fusion);GO:0090630(activation of GTPase activity);GO:0012505(endomembrane system);GO:0005929(cilium);GO:0043547(positive regulation of GTPase activity);GO:0036064(ciliary basal body);GO:0017137(Rab GTPase binding);GO:1902018(negative regulation of cilium assembly);GO:1902018(negative regulation of cilium assembly)","NA","NA","NA","TBC1 domain family member 30 [Source:HGNC Symbol;Acc:HGNC:29164]",{"v":0.178462479417206,"d":"0.18"},{"v":0.428650012719704,"d":"0.43"},{"v":0.416336111329835,"d":"0.42"},{"v":-1.264179397382,"d":"-1.26"},{"v":0.0729666962050609,"d":"0.07"},{"v":0.770738258493748,"d":"0.77"},"down","no"]
["MSTRG.9014","RNF149;SNORD89","ENST00000295317;ENST00000424632;ENST00000490553;ENST00000463726;ENST00000485752;ENST00000478404;ENST00000390981","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0046872(metal ion binding);GO:0016740(transferase activity);GO:0016567(protein ubiquitination);GO:0070062(extracellular exosome);GO:0061630(ubiquitin protein ligase activity);GO:0031647(regulation of protein stability);GO:0035690(cellular response to drug);GO:0043409(negative regulation of MAPK cascade);GO:0043409(negative regulation of MAPK cascade)","NA","NA","NA","ring finger protein 149 [Source:HGNC Symbol;Acc:HGNC:23137];small nucleolar RNA, C/D box 89 [Source:HGNC Symbol;Acc:HGNC:32750]",{"v":14.9049024760558,"d":"14.90"},{"v":34.5864611749848,"d":"34.59"},{"v":0.430946155510006,"d":"0.43"},{"v":-1.21442047158557,"d":"-1.21"},{"v":0.0731453004290405,"d":"0.07"},{"v":0.770738258493748,"d":"0.77"},"down","no"]
["MSTRG.8058","CEBPA","ENST00000498907","GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0005634(nucleus);GO:0043231(intracellular membrane-bounded organelle);GO:0005654(nucleoplasm);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0042803(protein homodimerization activity);GO:0005515(protein binding);GO:0007275(multicellular organism development);GO:0003713(transcription coactivator activity);GO:0005730(nucleolus);GO:0045444(fat cell differentiation);GO:0008285(negative regulation of cell proliferation);GO:0016032(viral process);GO:0008134(transcription factor binding);GO:0044212(transcription regulatory region DNA binding);GO:0045892(negative regulation of transcription, DNA-templated);GO:0006366(transcription from RNA polymerase II promoter);GO:0090575(RNA polymerase II transcription factor complex);GO:0006091(generation of precursor metabolites and energy);GO:0019221(cytokine-mediated signaling pathway);GO:0001889(liver development);GO:0019900(kinase binding);GO:0042593(glucose homeostasis);GO:0032436(positive regulation of proteasomal ubiquitin-dependent protein catabolic process);GO:0003705(transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding);GO:0045945(positive regulation of transcription from RNA polymerase III promoter);GO:0001228(transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding);GO:0030851(granulocyte differentiation);GO:0030324(lung development);GO:0055088(lipid homeostasis);GO:0030099(myeloid cell differentiation);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:0001077(transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0043565(sequence-specific DNA binding);GO:0000050(urea cycle);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0001892(embryonic placenta development);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0007005(mitochondrion organization);GO:0007219(Notch signaling pathway);GO:0008203(cholesterol metabolic process);GO:0030225(macrophage differentiation);GO:0042127(regulation of cell proliferation);GO:0045600(positive regulation of fat cell differentiation);GO:0045669(positive regulation of osteoblast differentiation);GO:0045736(negative regulation of cyclin-dependent protein serine/threonine kinase activity);GO:0045786(negative regulation of cell cycle);GO:0045893(positive regulation of transcription, DNA-templated);GO:0048469(cell maturation);GO:0048839(inner ear development);GO:0050872(white fat cell differentiation);GO:0050873(brown fat cell differentiation);GO:0071285(cellular response to lithium ion);GO:0071356(cellular response to tumor necrosis factor);GO:0071407(cellular response to organic cyclic compound);GO:0005667(transcription factor complex)","05200(Pathways in cancer);05202(Transcriptional misregulation in cancers);05221(Acute myeloid leukemia);04932(Non-alcoholic fatty liver disease (NAFLD))","K09055","NA","CCAAT/enhancer binding protein alpha [Source:HGNC Symbol;Acc:HGNC:1833]",{"v":3.553207,"d":"3.55"},{"v":8.278079,"d":"8.28"},{"v":0.429230863827224,"d":"0.43"},{"v":-1.22017427813687,"d":"-1.22"},{"v":0.0732185033542499,"d":"0.07"},{"v":0.770738258493748,"d":"0.77"},"down","no"]
["MSTRG.7701","PLIN3","ENST00000221957;ENST00000589034;ENST00000587462;ENST00000592528;ENST00000589163;ENST00000585479","GO:0006810(transport);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005829(cytosol);GO:0005515(protein binding);GO:0005811(lipid particle);GO:0005768(endosome);GO:0045296(cadherin binding);GO:0010008(endosome membrane);GO:0016192(vesicle-mediated transport);GO:0005794(Golgi apparatus);GO:0030133(transport vesicle);GO:0030133(transport vesicle)","NA","NA","NA","perilipin 3 [Source:HGNC Symbol;Acc:HGNC:16893]",{"v":3.96888079488091,"d":"3.97"},{"v":9.24177859900462,"d":"9.24"},{"v":0.429449889148868,"d":"0.43"},{"v":-1.21943829622247,"d":"-1.22"},{"v":0.0732266679825173,"d":"0.07"},{"v":0.770738258493748,"d":"0.77"},"down","no"]
["MSTRG.3982","ZC3H13","ENST00000242848;ENST00000282007;ENST00000428921;ENST00000464597;ENST00000470308","GO:0003723(RNA binding);GO:0005634(nucleus);GO:0016607(nuclear speck);GO:0046872(metal ion binding);GO:0005515(protein binding);GO:0005654(nucleoplasm);GO:0005654(nucleoplasm)","NA","NA","NA","zinc finger CCCH-type containing 13 [Source:HGNC Symbol;Acc:HGNC:20368]",{"v":6.57498822903069,"d":"6.57"},{"v":2.93787361841208,"d":"2.94"},{"v":2.23800921449591,"d":"2.24"},{"v":1.16221597629652,"d":"1.16"},{"v":0.0732615064245778,"d":"0.07"},{"v":0.770738258493748,"d":"0.77"},"up","no"]
["MSTRG.9932","FP671120.1","MSTRG.9932.1","NA","NA","NA","NA",null,{"v":142.92778,"d":"142.93"},{"v":63.857643,"d":"63.86"},{"v":2.23822510956128,"d":"2.24"},{"v":1.1623551427109,"d":"1.16"},{"v":0.0732847787722423,"d":"0.07"},{"v":0.770738258493748,"d":"0.77"},"up","no"]
["MSTRG.10044","ETS2","ENST00000360938;ENST00000456966;ENST00000360214;ENST00000432278","GO:0005634(nucleus);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0005886(plasma membrane);GO:0043565(sequence-specific DNA binding);GO:0005515(protein binding);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:0001078(transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0030154(cell differentiation);GO:0045893(positive regulation of transcription, DNA-templated);GO:0019904(protein domain specific binding);GO:0001501(skeletal system development);GO:0000977(RNA polymerase II regulatory region sequence-specific DNA binding);GO:0035259(glucocorticoid receptor binding);GO:0001712(ectodermal cell fate commitment);GO:0007498(mesoderm development);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0090009(primitive streak formation);GO:0090009(primitive streak formation)","04014(Ras signaling pathway);05166(HTLV-I infection);05166(HTLV-I infection)","K21932","NA","ETS proto-oncogene 2, transcription factor [Source:HGNC Symbol;Acc:HGNC:3489]",{"v":4.87426289401523,"d":"4.87"},{"v":11.3074037096844,"d":"11.31"},{"v":0.431068264577888,"d":"0.43"},{"v":-1.214011740261,"d":"-1.21"},{"v":0.0734116810575763,"d":"0.07"},{"v":0.770753916167509,"d":"0.77"},"down","no"]
["MSTRG.3017","TIGAR","ENST00000179259;ENST00000539671;ENST00000635110","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0016787(hydrolase activity);GO:0003824(catalytic activity);GO:0008152(metabolic process);GO:0016311(dephosphorylation);GO:0005739(mitochondrion);GO:0006974(cellular response to DNA damage stimulus);GO:0006915(apoptotic process);GO:0005741(mitochondrial outer membrane);GO:0006914(autophagy);GO:0005515(protein binding);GO:0004331(fructose-2,6-bisphosphate 2-phosphatase activity);GO:0002931(response to ischemia);GO:0071456(cellular response to hypoxia);GO:0005622(intracellular);GO:0045739(positive regulation of DNA repair);GO:0043069(negative regulation of programmed cell death);GO:0030388(fructose 1,6-bisphosphate metabolic process);GO:0006003(fructose 2,6-bisphosphate metabolic process);GO:0043456(regulation of pentose-phosphate shunt);GO:0004083(bisphosphoglycerate 2-phosphatase activity);GO:0009410(response to xenobiotic stimulus);GO:0010332(response to gamma radiation);GO:0010666(positive regulation of cardiac muscle cell apoptotic process);GO:0045820(negative regulation of glycolytic process);GO:0060576(intestinal epithelial cell development);GO:0071279(cellular response to cobalt ion);GO:1901215(negative regulation of neuron death);GO:1901525(negative regulation of macromitophagy);GO:1902153(regulation of response to DNA damage checkpoint signaling);GO:1903301(positive regulation of hexokinase activity);GO:1904024(negative regulation of glucose catabolic process to lactate via pyruvate);GO:2000378(negative regulation of reactive oxygen species metabolic process);GO:2000378(negative regulation of reactive oxygen species metabolic process)","00051(Fructose and mannose metabolism);05230(Central carbon metabolism in cancer);05230(Central carbon metabolism in cancer)","K14634","EC:3.1.3.46","TP53 induced glycolysis regulatory phosphatase [Source:HGNC Symbol;Acc:HGNC:1185]",{"v":0.583760675130695,"d":"0.58"},{"v":1.38494812471994,"d":"1.38"},{"v":0.421503639530716,"d":"0.42"},{"v":-1.24638300651895,"d":"-1.25"},{"v":0.0734142785122183,"d":"0.07"},{"v":0.770753916167509,"d":"0.77"},"down","no"]
["MSTRG.10083","ITGB2-AS1","MSTRG.10083.7;ENST00000609694;ENST00000441379;ENST00000609592;ENST00000429132;ENST00000608043","NA","NA","NA","NA","ITGB2 antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:44304]",{"v":9.03996278557273,"d":"9.04"},{"v":4.03430406302021,"d":"4.03"},{"v":2.24077378510858,"d":"2.24"},{"v":1.1639970104837,"d":"1.16"},{"v":0.073555030821499,"d":"0.07"},{"v":0.771558955707744,"d":"0.77"},"up","no"]
["ENSG00000135407","AVIL","ENST00000549851;ENST00000546952;ENST00000257861;ENST00000549753;ENST00000549994;ENST00000548843;ENST00000550537;ENST00000549548;ENST00000551248","GO:0005737(cytoplasm);GO:0003779(actin binding);GO:0051015(actin filament binding);GO:0051693(actin filament capping);GO:0005856(cytoskeleton);GO:0042995(cell projection);GO:0007010(cytoskeleton organization);GO:0010975(regulation of neuron projection development);GO:0030424(axon);GO:0060271(cilium assembly);GO:0007399(nervous system development);GO:0043005(neuron projection);GO:0015629(actin cytoskeleton);GO:0010976(positive regulation of neuron projection development);GO:0010976(positive regulation of neuron projection development)","NA","NA","NA","advillin [Source:HGNC Symbol;Acc:HGNC:14188]",{"v":0.507805534216336,"d":"0.51"},{"v":1.20137467057225,"d":"1.20"},{"v":0.422687065621629,"d":"0.42"},{"v":-1.24233812883765,"d":"-1.24"},{"v":0.0736313501348769,"d":"0.07"},{"v":0.771687309246464,"d":"0.77"},"down","no"]
["ENSG00000120949","TNFRSF8","ENST00000413146;ENST00000263932;ENST00000417814","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0007165(signal transduction);GO:0005886(plasma membrane);GO:0004888(transmembrane signaling receptor activity);GO:0006955(immune response);GO:0005634(nucleus);GO:0005887(integral component of plasma membrane);GO:0006954(inflammatory response);GO:0070062(extracellular exosome);GO:0097190(apoptotic signaling pathway);GO:0033209(tumor necrosis factor-mediated signaling pathway);GO:0043065(positive regulation of apoptotic process);GO:0007411(axon guidance);GO:0043005(neuron projection);GO:0042535(positive regulation of tumor necrosis factor biosynthetic process);GO:0071260(cellular response to mechanical stimulus);GO:0005031(tumor necrosis factor-activated receptor activity);GO:0032496(response to lipopolysaccharide);GO:0008285(negative regulation of cell proliferation);GO:0048406(nerve growth factor binding);GO:0010977(negative regulation of neuron projection development);GO:0045556(positive regulation of TRAIL biosynthetic process);GO:0045556(positive regulation of TRAIL biosynthetic process)","04060(Cytokine-cytokine receptor interaction);04060(Cytokine-cytokine receptor interaction)","K05145","NA","TNF receptor superfamily member 8 [Source:HGNC Symbol;Acc:HGNC:11923]",{"v":0.266566182182986,"d":"0.27"},{"v":0.65182742482611,"d":"0.65"},{"v":0.408952081533082,"d":"0.41"},{"v":-1.28999628786862,"d":"-1.29"},{"v":0.0737647665993262,"d":"0.07"},{"v":0.771874270836216,"d":"0.77"},"down","no"]
["MSTRG.12864","LST1","ENST00000438075;MSTRG.12864.9;MSTRG.12864.4;MSTRG.12864.8;ENST00000418507;ENST00000376099;ENST00000376089;ENST00000376096;ENST00000376090;ENST00000464526;ENST00000376093;ENST00000396112;MSTRG.12864.3;ENST00000303757;ENST00000396101;ENST00000376092;ENST00000490742;ENST00000464044;MSTRG.12864.2;ENST00000376110;ENST00000433492;MSTRG.12864.1;ENST00000339530;ENST00000460834;ENST00000419073;ENST00000376086;ENST00000211921","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005794(Golgi apparatus);GO:0006955(immune response);GO:0000139(Golgi membrane);GO:0002376(immune system process);GO:0000902(cell morphogenesis);GO:0012505(endomembrane system);GO:0008360(regulation of cell shape);GO:0016358(dendrite development);GO:0009653(anatomical structure morphogenesis);GO:0050672(negative regulation of lymphocyte proliferation);GO:0050672(negative regulation of lymphocyte proliferation)","NA","NA","NA","leukocyte specific transcript 1 [Source:HGNC Symbol;Acc:HGNC:14189]",{"v":17.2781070919425,"d":"17.28"},{"v":40.0842576399198,"d":"40.08"},{"v":0.431044707055652,"d":"0.43"},{"v":-1.21409058449983,"d":"-1.21"},{"v":0.0738574480440779,"d":"0.07"},{"v":0.771874270836216,"d":"0.77"},"down","no"]
["MSTRG.10860","ZNF445;LINC00694","ENST00000396077;ENST00000634610;ENST00000617032;ENST00000637612;ENST00000636468;ENST00000416124;MSTRG.10860.5;ENST00000474600;ENST00000460529","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0005622(intracellular);GO:0070062(extracellular exosome);GO:0070062(extracellular exosome)","NA","NA","NA","zinc finger protein 445 [Source:HGNC Symbol;Acc:HGNC:21018];long intergenic non-protein coding RNA 694 [Source:HGNC Symbol;Acc:HGNC:44570]",{"v":0.474788579602115,"d":"0.47"},{"v":1.1051181225384,"d":"1.11"},{"v":0.429626996353611,"d":"0.43"},{"v":-1.21884344448353,"d":"-1.22"},{"v":0.0738765522957899,"d":"0.07"},{"v":0.771874270836216,"d":"0.77"},"down","no"]
["ENSG00000101247","NDUFAF5","ENST00000464269;ENST00000481249;ENST00000485738;ENST00000486772;ENST00000476200;ENST00000475968;ENST00000476536;ENST00000463598;ENST00000487478;ENST00000469177;ENST00000378081;ENST00000479682;ENST00000378106","GO:0016020(membrane);GO:0008168(methyltransferase activity);GO:0016740(transferase activity);GO:0032259(methylation);GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0005743(mitochondrial inner membrane);GO:0008152(metabolic process);GO:0005739(mitochondrion);GO:0005515(protein binding);GO:0003674(molecular_function);GO:0032981(mitochondrial respiratory chain complex I assembly);GO:0031314(extrinsic component of mitochondrial inner membrane);GO:0030961(peptidyl-arginine hydroxylation);GO:0030961(peptidyl-arginine hydroxylation)","NA","NA","NA","NADH:ubiquinone oxidoreductase complex assembly factor 5 [Source:HGNC Symbol;Acc:HGNC:15899]",{"v":0.0868001776361369,"d":"0.09"},{"v":0.223692504087571,"d":"0.22"},{"v":0.388033465806956,"d":"0.39"},{"v":-1.36574701239329,"d":"-1.37"},{"v":0.0739055833145788,"d":"0.07"},{"v":0.771874270836216,"d":"0.77"},"down","no"]
["MSTRG.12351","FAM53C","ENST00000239906;ENST00000513056;ENST00000512180;ENST00000505136;ENST00000434981;ENST00000511024","GO:0005515(protein binding);GO:0005515(protein binding)","NA","NA","NA","family with sequence similarity 53 member C [Source:HGNC Symbol;Acc:HGNC:1336]",{"v":6.28294024748263,"d":"6.28"},{"v":14.5322123183946,"d":"14.53"},{"v":0.432345750930834,"d":"0.43"},{"v":-1.20974258424088,"d":"-1.21"},{"v":0.0742290247747188,"d":"0.07"},{"v":0.774245413320705,"d":"0.77"},"down","no"]
["MSTRG.14574","FAM49B","MSTRG.14574.12;MSTRG.14574.13;MSTRG.14574.2;ENST00000523288;ENST00000517654;ENST00000518167;ENST00000519142;ENST00000639004;ENST00000523509;ENST00000519824;ENST00000523514;ENST00000522746;ENST00000521223;ENST00000520204;ENST00000517801;ENST00000522250;ENST00000519070;ENST00000522702;ENST00000519110;ENST00000522941;ENST00000518285;ENST00000518879;ENST00000615041;ENST00000518344;ENST00000522361;ENST00000519020;ENST00000523993;ENST00000520254;ENST00000401979;ENST00000520887;ENST00000519540;ENST00000518283","GO:0016020(membrane);GO:0005515(protein binding);GO:0023030(MHC class Ib protein binding, via antigen binding groove);GO:0001916(positive regulation of T cell mediated cytotoxicity);GO:0032729(positive regulation of interferon-gamma production);GO:0050870(positive regulation of T cell activation);GO:2000568(positive regulation of memory T cell activation);GO:0005929(cilium);GO:0005576(extracellular region);GO:0070062(extracellular exosome);GO:0002576(platelet degranulation);GO:0031093(platelet alpha granule lumen);GO:0031093(platelet alpha granule lumen)","NA","NA","NA","family with sequence similarity 49 member B [Source:HGNC Symbol;Acc:HGNC:25216]",{"v":6.70075168889619,"d":"6.70"},{"v":15.513886586947,"d":"15.51"},{"v":0.431919599988183,"d":"0.43"},{"v":-1.21116530910381,"d":"-1.21"},{"v":0.0742612068082888,"d":"0.07"},{"v":0.774245413320705,"d":"0.77"},"down","no"]
["MSTRG.6407","AC104581.5;CYB5D1","ENST00000624171;ENST00000574196;ENST00000571846;ENST00000573940;ENST00000332439;ENST00000574357","GO:0046872(metal ion binding);GO:0046872(metal ion binding)","NA","NA","NA","cytochrome b5 domain containing 1 [Source:HGNC Symbol;Acc:HGNC:26516]",{"v":0.306661081995134,"d":"0.31"},{"v":0.131668154379562,"d":"0.13"},{"v":2.32904519274355,"d":"2.33"},{"v":1.21973863384437,"d":"1.22"},{"v":0.0743450658539297,"d":"0.07"},{"v":0.774449206758669,"d":"0.77"},"up","no"]
["MSTRG.10552","CYB5R3","ENST00000352397;MSTRG.10552.4;ENST00000407332;ENST00000466276;ENST00000407623;ENST00000402438;ENST00000361740;ENST00000438270;ENST00000470741","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005783(endoplasmic reticulum);GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0006629(lipid metabolic process);GO:0005789(endoplasmic reticulum membrane);GO:0005739(mitochondrion);GO:0006694(steroid biosynthetic process);GO:0008202(steroid metabolic process);GO:0016126(sterol biosynthetic process);GO:0005741(mitochondrial outer membrane);GO:0008203(cholesterol metabolic process);GO:0005576(extracellular region);GO:0006695(cholesterol biosynthetic process);GO:0070062(extracellular exosome);GO:0006805(xenobiotic metabolic process);GO:0043312(neutrophil degranulation);GO:0035578(azurophil granule lumen);GO:0005811(lipid particle);GO:0008015(blood circulation);GO:0019852(L-ascorbic acid metabolic process);GO:0004128(cytochrome-b5 reductase activity, acting on NAD(P)H);GO:0005833(hemoglobin complex);GO:0016208(AMP binding);GO:0043531(ADP binding);GO:0050660(flavin adenine dinucleotide binding);GO:0051287(NAD binding);GO:0005743(mitochondrial inner membrane);GO:0005743(mitochondrial inner membrane)","00520(Amino sugar and nucleotide sugar metabolism);00520(Amino sugar and nucleotide sugar metabolism)","K00326","EC:1.6.2.2","cytochrome b5 reductase 3 [Source:HGNC Symbol;Acc:HGNC:2873]",{"v":5.99106597170601,"d":"5.99"},{"v":13.8591568012724,"d":"13.86"},{"v":0.43228214079777,"d":"0.43"},{"v":-1.20995486058442,"d":"-1.21"},{"v":0.0745482116900971,"d":"0.07"},{"v":0.774602335788124,"d":"0.77"},"down","no"]
["MSTRG.6949","NPEPPS","ENST00000322157;MSTRG.6949.1;ENST00000531486;ENST00000525007;ENST00000532729;ENST00000534807;ENST00000528565;ENST00000602788;ENST00000527824;ENST00000529602;ENST00000527298;ENST00000534691;ENST00000526247;ENST00000534727;ENST00000534814;ENST00000528751;ENST00000525037;ENST00000525021;ENST00000525048;ENST00000533538;ENST00000530514;ENST00000527964;ENST00000525401","GO:0006508(proteolysis);GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0005829(cytosol);GO:0016787(hydrolase activity);GO:0008233(peptidase activity);GO:0008237(metallopeptidase activity);GO:0004177(aminopeptidase activity);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0070062(extracellular exosome);GO:0000209(protein polyubiquitination);GO:1903955(positive regulation of protein targeting to mitochondrion);GO:0071456(cellular response to hypoxia);GO:0042277(peptide binding);GO:0070006(metalloaminopeptidase activity);GO:0043171(peptide catabolic process);GO:0043171(peptide catabolic process)","NA","NA","NA","aminopeptidase puromycin sensitive [Source:HGNC Symbol;Acc:HGNC:7900]",{"v":2.33387850382143,"d":"2.33"},{"v":5.40344319159284,"d":"5.40"},{"v":0.431924315860799,"d":"0.43"},{"v":-1.21114955726274,"d":"-1.21"},{"v":0.0745915715282613,"d":"0.07"},{"v":0.774602335788124,"d":"0.77"},"down","no"]
["ENSG00000055955","ITIH4","ENST00000266041;ENST00000464000;ENST00000485816;ENST00000461966;ENST00000491663;ENST00000471505;ENST00000485894;ENST00000481977;ENST00000441637;ENST00000406595;ENST00000473904","GO:0004867(serine-type endopeptidase inhibitor activity);GO:0010951(negative regulation of endopeptidase activity);GO:0005576(extracellular region);GO:0030414(peptidase inhibitor activity);GO:0010466(negative regulation of peptidase activity);GO:0030212(hyaluronan metabolic process);GO:0005515(protein binding);GO:0070062(extracellular exosome);GO:0072562(blood microparticle);GO:0006953(acute-phase response);GO:0002576(platelet degranulation);GO:0004866(endopeptidase inhibitor activity);GO:0034097(response to cytokine);GO:0031089(platelet dense granule lumen);GO:0005737(cytoplasm);GO:0005886(plasma membrane);GO:0005886(plasma membrane)","NA","NA","NA","inter-alpha-trypsin inhibitor heavy chain family member 4 [Source:HGNC Symbol;Acc:HGNC:6169]",{"v":0.558976096484804,"d":"0.56"},{"v":0.242106254485536,"d":"0.24"},{"v":2.30880485790258,"d":"2.31"},{"v":1.20714624048601,"d":"1.21"},{"v":0.0748498101625906,"d":"0.07"},{"v":0.774602335788124,"d":"0.77"},"up","no"]
["ENSG00000186648","CARMIL3","ENST00000342740;ENST00000560349;ENST00000559694;ENST00000561354","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005886(plasma membrane);GO:0005886(plasma membrane)","NA","NA","NA","capping protein regulator and myosin 1 linker 3 [Source:HGNC Symbol;Acc:HGNC:20272]",{"v":0.399048109827457,"d":"0.40"},{"v":0.1740280048012,"d":"0.17"},{"v":2.29301088800798,"d":"2.29"},{"v":1.19724320534951,"d":"1.20"},{"v":0.0748707409785227,"d":"0.07"},{"v":0.774602335788124,"d":"0.77"},"up","no"]
["MSTRG.12830","FLOT1","ENST00000484168;MSTRG.12830.3;MSTRG.12830.4;ENST00000476729;ENST00000470643;ENST00000487376;ENST00000376389;ENST00000484693;ENST00000445853;ENST00000413165;ENST00000418160;ENST00000438162;ENST00000454845","GO:0016020(membrane);GO:0005765(lysosomal membrane);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0042470(melanosome);GO:0005901(caveola);GO:0031410(cytoplasmic vesicle);GO:0045121(membrane raft);GO:0005925(focal adhesion);GO:0005768(endosome);GO:0030027(lamellipodium);GO:0070062(extracellular exosome);GO:0001934(positive regulation of protein phosphorylation);GO:0050821(protein stabilization);GO:0022617(extracellular matrix disassembly);GO:0008180(COP9 signalosome);GO:0016323(basolateral plasma membrane);GO:0001819(positive regulation of cytokine production);GO:0005769(early endosome);GO:0016021(integral component of membrane);GO:0002020(protease binding);GO:0032092(positive regulation of protein binding);GO:0046982(protein heterodimerization activity);GO:0034976(response to endoplasmic reticulum stress);GO:0030864(cortical actin cytoskeleton);GO:0045807(positive regulation of endocytosis);GO:0032728(positive regulation of interferon-beta production);GO:1901741(positive regulation of myoblast fusion);GO:0090002(establishment of protein localization to plasma membrane);GO:0005911(cell-cell junction);GO:0001931(uropod);GO:0051260(protein homooligomerization);GO:0016600(flotillin complex);GO:0035255(ionotropic glutamate receptor binding);GO:0001765(membrane raft assembly);GO:0002090(regulation of receptor internalization);GO:0007409(axonogenesis);GO:0032226(positive regulation of synaptic transmission, dopaminergic);GO:0033227(dsRNA transport);GO:0034116(positive regulation of heterotypic cell-cell adhesion);GO:0034141(positive regulation of toll-like receptor 3 signaling pathway);GO:0035023(regulation of Rho protein signal transduction);GO:0044854(plasma membrane raft assembly);GO:0048643(positive regulation of skeletal muscle tissue development);GO:0060355(positive regulation of cell adhesion molecule production);GO:0070528(protein kinase C signaling);GO:0071360(cellular response to exogenous dsRNA);GO:0072659(protein localization to plasma membrane);GO:1901890(positive regulation of cell junction assembly);GO:1903044(protein localization to membrane raft);GO:2000049(positive regulation of cell-cell adhesion mediated by cadherin);GO:0005815(microtubule organizing center);GO:0005913(cell-cell adherens junction);GO:0034451(centriolar satellite);GO:0042383(sarcolemma);GO:0044291(cell-cell contact zone);GO:0044853(plasma membrane raft);GO:0044853(plasma membrane raft)","04910(Insulin signaling pathway);04910(Insulin signaling pathway)","K07192","NA","flotillin 1 [Source:HGNC Symbol;Acc:HGNC:3757]",{"v":25.096152703076,"d":"25.10"},{"v":57.9297297614564,"d":"57.93"},{"v":0.433217154756585,"d":"0.43"},{"v":-1.20683772222683,"d":"-1.21"},{"v":0.0748760295045269,"d":"0.07"},{"v":0.774602335788124,"d":"0.77"},"down","no"]
["ENSG00000203950","RTL8A","ENST00000370775;ENST00000518153;ENST00000520964","GO:0005515(protein binding);GO:0005515(protein binding)","NA","NA","NA","retrotransposon Gag like 8A [Source:HGNC Symbol;Acc:HGNC:24514]",{"v":3.55776752885375,"d":"3.56"},{"v":1.56283316916996,"d":"1.56"},{"v":2.27648580733881,"d":"2.28"},{"v":1.18680846495969,"d":"1.19"},{"v":0.0749093543808369,"d":"0.07"},{"v":0.774602335788124,"d":"0.77"},"up","no"]
["MSTRG.400","AL513327.1","ENST00000630229;ENST00000628643;ENST00000630909;ENST00000627130","NA","NA","NA","NA",null,{"v":0.289837088418431,"d":"0.29"},{"v":0.698859155666251,"d":"0.70"},{"v":0.414728899333253,"d":"0.41"},{"v":-1.26975951358971,"d":"-1.27"},{"v":0.0749628781166744,"d":"0.07"},{"v":0.774602335788124,"d":"0.77"},"down","no"]
["MSTRG.284","ZDHHC18","ENST00000374142;ENST00000478902;ENST00000534643;ENST00000488397;ENST00000374141","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016740(transferase activity);GO:0005794(Golgi apparatus);GO:0016746(transferase activity, transferring acyl groups);GO:0019706(protein-cysteine S-palmitoyltransferase activity);GO:0016409(palmitoyltransferase activity);GO:0018345(protein palmitoylation);GO:0034613(cellular protein localization);GO:0034613(cellular protein localization)","NA","NA","NA","zinc finger DHHC-type containing 18 [Source:HGNC Symbol;Acc:HGNC:20712]",{"v":21.9433216122149,"d":"21.94"},{"v":50.6030250158205,"d":"50.60"},{"v":0.433636558394573,"d":"0.43"},{"v":-1.20544170445199,"d":"-1.21"},{"v":0.0750690301131446,"d":"0.08"},{"v":0.774602335788124,"d":"0.77"},"down","no"]
["ENSG00000120280","CXorf21","ENST00000378962","NA","NA","NA","NA","chromosome X open reading frame 21 [Source:HGNC Symbol;Acc:HGNC:25667]",{"v":3.226274,"d":"3.23"},{"v":1.4308,"d":"1.43"},{"v":2.25487419625384,"d":"2.25"},{"v":1.17304694500898,"d":"1.17"},{"v":0.0751133685940337,"d":"0.08"},{"v":0.774602335788124,"d":"0.77"},"up","no"]
["ENSG00000182195","LDOC1","ENST00000370526","GO:0005634(nucleus);GO:0005730(nucleolus);GO:0005515(protein binding);GO:0008285(negative regulation of cell proliferation);GO:0001893(maternal placenta development);GO:0060137(maternal process involved in parturition);GO:1903547(regulation of growth hormone activity)","NA","NA","NA","LDOC1, regulator of NFKB signaling [Source:HGNC Symbol;Acc:HGNC:6548]",{"v":1.503847,"d":"1.50"},{"v":0.642236,"d":"0.64"},{"v":2.34158004222747,"d":"2.34"},{"v":1.22748235452254,"d":"1.23"},{"v":0.0751584911565546,"d":"0.08"},{"v":0.774602335788124,"d":"0.77"},"up","no"]
["MSTRG.15089","NACC2","ENST00000371753;MSTRG.15089.1;ENST00000467669","GO:0008285(negative regulation of cell proliferation);GO:0005634(nucleus);GO:0005730(nucleolus);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0016575(histone deacetylation);GO:0005739(mitochondrion);GO:0005515(protein binding);GO:0008284(positive regulation of cell proliferation);GO:0042803(protein homodimerization activity);GO:0045892(negative regulation of transcription, DNA-templated);GO:0000790(nuclear chromatin);GO:0001078(transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0034629(cellular protein complex localization);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:0042826(histone deacetylase binding);GO:0051260(protein homooligomerization);GO:0016604(nuclear body);GO:0016581(NuRD complex);GO:0001076(transcription factor activity, RNA polymerase II transcription factor binding);GO:0004407(histone deacetylase activity);GO:0010608(posttranscriptional regulation of gene expression);GO:1900477(negative regulation of G1/S transition of mitotic cell cycle by negative regulation of transcription from RNA polymerase II promoter);GO:1902231(positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage);GO:1902231(positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage)","NA","NA","NA","NACC family member 2 [Source:HGNC Symbol;Acc:HGNC:23846]",{"v":3.1943934156233,"d":"3.19"},{"v":7.37541285819271,"d":"7.38"},{"v":0.433113844206691,"d":"0.43"},{"v":-1.20718180692168,"d":"-1.21"},{"v":0.0751602817946819,"d":"0.08"},{"v":0.774602335788124,"d":"0.77"},"down","no"]
["ENSG00000123989","CHPF","ENST00000243776;ENST00000373891;ENST00000535926","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0046872(metal ion binding);GO:0016740(transferase activity);GO:0005794(Golgi apparatus);GO:0005829(cytosol);GO:0005739(mitochondrion);GO:0005759(mitochondrial matrix);GO:0008376(acetylgalactosaminyltransferase activity);GO:0032580(Golgi cisterna membrane);GO:0000139(Golgi membrane);GO:0030206(chondroitin sulfate biosynthetic process);GO:0047238(glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity);GO:0050510(N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity);GO:0016757(transferase activity, transferring glycosyl groups);GO:0016757(transferase activity, transferring glycosyl groups)","00532(Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate);00532(Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate)","K00747","EC:2.4.1.175;EC:2.4.1.226","chondroitin polymerizing factor [Source:HGNC Symbol;Acc:HGNC:24291]",{"v":1.26010211568277,"d":"1.26"},{"v":0.557443314549791,"d":"0.56"},{"v":2.26050269649474,"d":"2.26"},{"v":1.17664363861123,"d":"1.18"},{"v":0.0752498096532363,"d":"0.08"},{"v":0.774602335788124,"d":"0.77"},"up","no"]
["ENSG00000100731","PCNX1","ENST00000304743;ENST00000439984;ENST00000556516;ENST00000556846;ENST00000554292;ENST00000553508;ENST00000557428;ENST00000554879;ENST00000556272;ENST00000553428;ENST00000555780;ENST00000553272;ENST00000556849","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016021(integral component of membrane)","NA","NA","NA","pecanex homolog 1 [Source:HGNC Symbol;Acc:HGNC:19740]",{"v":2.97366597038588,"d":"2.97"},{"v":6.86035914262638,"d":"6.86"},{"v":0.433456311625029,"d":"0.43"},{"v":-1.20604150438876,"d":"-1.21"},{"v":0.0752684903454855,"d":"0.08"},{"v":0.774602335788124,"d":"0.77"},"down","no"]
["ENSG00000134955","SLC37A2","ENST00000526405;ENST00000403796;ENST00000525837","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005215(transporter activity);GO:0055085(transmembrane transport);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0015297(antiporter activity);GO:0008643(carbohydrate transport);GO:0070062(extracellular exosome);GO:0030176(integral component of endoplasmic reticulum membrane);GO:0015760(glucose-6-phosphate transport);GO:0061513(glucose 6-phosphate:inorganic phosphate antiporter activity);GO:0035435(phosphate ion transmembrane transport);GO:0035435(phosphate ion transmembrane transport)","NA","NA","NA","solute carrier family 37 member 2 [Source:HGNC Symbol;Acc:HGNC:20644]",{"v":1.21961313137655,"d":"1.22"},{"v":2.83007374917595,"d":"2.83"},{"v":0.430947473270501,"d":"0.43"},{"v":-1.21441606007476,"d":"-1.21"},{"v":0.0752787020775115,"d":"0.08"},{"v":0.774602335788124,"d":"0.77"},"down","no"]
["ENSG00000178814","OPLAH","ENST00000618853;ENST00000527993;ENST00000531027","GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0016787(hydrolase activity);GO:0003824(catalytic activity);GO:0005829(cytosol);GO:0006749(glutathione metabolic process);GO:0017168(5-oxoprolinase (ATP-hydrolyzing) activity);GO:0006750(glutathione biosynthetic process);GO:0006750(glutathione biosynthetic process)","00480(Glutathione metabolism);00480(Glutathione metabolism)","K01469","EC:3.5.2.9","5-oxoprolinase (ATP-hydrolysing) [Source:HGNC Symbol;Acc:HGNC:8149]",{"v":0.482444241015274,"d":"0.48"},{"v":1.13330664173405,"d":"1.13"},{"v":0.425696120757834,"d":"0.43"},{"v":-1.23210415155876,"d":"-1.23"},{"v":0.0753246416880828,"d":"0.08"},{"v":0.774602335788124,"d":"0.77"},"down","no"]
["MSTRG.1035","MTX1","ENST00000481771;ENST00000609421;ENST00000368376;ENST00000495492;ENST00000316721;ENST00000424959","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005741(mitochondrial outer membrane);GO:0006626(protein targeting to mitochondrion);GO:0006810(transport);GO:0015031(protein transport);GO:0005739(mitochondrion);GO:0005739(mitochondrion)","NA","NA","NA","metaxin 1 [Source:HGNC Symbol;Acc:HGNC:7504]",{"v":2.58491393166565,"d":"2.58"},{"v":5.99307220561318,"d":"5.99"},{"v":0.431317001194244,"d":"0.43"},{"v":-1.21317951107737,"d":"-1.21"},{"v":0.0756512227074746,"d":"0.08"},{"v":0.777296948671851,"d":"0.78"},"down","no"]
["ENSG00000143702","CEP170","ENST00000336415;ENST00000366542;ENST00000523581;ENST00000468254;ENST00000413359;ENST00000522522;ENST00000481987;ENST00000366544;ENST00000521911;ENST00000522191;ENST00000522895;ENST00000366543;ENST00000490813;ENST00000522995;ENST00000476661;ENST00000469646;ENST00000468697;ENST00000464936","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005829(cytosol);GO:0005813(centrosome);GO:0005737(cytoplasm);GO:0031965(nuclear membrane);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0005874(microtubule);GO:0005819(spindle);GO:0005814(centriole);GO:0005814(centriole)","NA","NA","NA","centrosomal protein 170 [Source:HGNC Symbol;Acc:HGNC:28920]",{"v":0.972054412103483,"d":"0.97"},{"v":2.25290860362007,"d":"2.25"},{"v":0.431466421026376,"d":"0.43"},{"v":-1.21267980918827,"d":"-1.21"},{"v":0.0757404994246591,"d":"0.08"},{"v":0.777550804835247,"d":"0.78"},"down","no"]
["MSTRG.14704","C9orf72","ENST00000488117;ENST00000379997;ENST00000379995;ENST00000619707;ENST00000380003;ENST00000461679","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0043547(positive regulation of GTPase activity);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0005615(extracellular space);GO:0006914(autophagy);GO:0031410(cytoplasmic vesicle);GO:0005764(lysosome);GO:0005085(guanyl-nucleotide exchange factor activity);GO:0005768(endosome);GO:0006897(endocytosis);GO:0017112(Rab guanyl-nucleotide exchange factor activity);GO:0005776(autophagosome);GO:0010506(regulation of autophagy);GO:0017137(Rab GTPase binding);GO:1903432(regulation of TORC1 signaling);GO:1990316(ATG1/ULK1 kinase complex);GO:0032045(guanyl-nucleotide exchange factor complex);GO:0016239(positive regulation of macroautophagy);GO:0016239(positive regulation of macroautophagy)","NA","NA","NA","chromosome 9 open reading frame 72 [Source:HGNC Symbol;Acc:HGNC:28337]",{"v":2.1465131360937,"d":"2.15"},{"v":4.95407198399868,"d":"4.95"},{"v":0.433282589156313,"d":"0.43"},{"v":-1.20661982975811,"d":"-1.21"},{"v":0.0758324688691862,"d":"0.08"},{"v":0.777736983611489,"d":"0.78"},"down","no"]
["MSTRG.3022","TNFRSF1A","ENST00000162749;ENST00000366159;ENST00000535038;ENST00000440083;ENST00000543359;ENST00000534885;ENST00000536717;ENST00000539372;ENST00000535958;ENST00000536194;ENST00000540022;ENST00000437813;ENST00000538363;ENST00000543995;ENST00000543048","GO:0005615(extracellular space);GO:0050728(negative regulation of inflammatory response);GO:0042531(positive regulation of tyrosine phosphorylation of STAT protein);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0007165(signal transduction);GO:0005794(Golgi apparatus);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0006915(apoptotic process);GO:0000139(Golgi membrane);GO:0006954(inflammatory response);GO:0033209(tumor necrosis factor-mediated signaling pathway);GO:0006955(immune response);GO:0005739(mitochondrion);GO:0016032(viral process);GO:0005887(integral component of plasma membrane);GO:0043123(positive regulation of I-kappaB kinase/NF-kappaB signaling);GO:0005031(tumor necrosis factor-activated receptor activity);GO:0006693(prostaglandin metabolic process);GO:0007249(I-kappaB kinase/NF-kappaB signaling);GO:0071260(cellular response to mechanical stimulus);GO:0032496(response to lipopolysaccharide);GO:0042127(regulation of cell proliferation);GO:0042981(regulation of apoptotic process);GO:0050729(positive regulation of inflammatory response);GO:0090002(establishment of protein localization to plasma membrane);GO:0010803(regulation of tumor necrosis factor-mediated signaling pathway);GO:1903140(regulation of establishment of endothelial barrier);GO:0019221(cytokine-mediated signaling pathway);GO:0043235(receptor complex);GO:0045121(membrane raft);GO:2000304(positive regulation of ceramide biosynthetic process);GO:0008625(extrinsic apoptotic signaling pathway via death domain receptors);GO:0071550(death-inducing signaling complex assembly);GO:0043120(tumor necrosis factor binding);GO:0006952(defense response);GO:0007166(cell surface receptor signaling pathway);GO:0008630(intrinsic apoptotic signaling pathway in response to DNA damage);GO:0042742(defense response to bacterium);GO:0009986(cell surface);GO:0009986(cell surface)","04010(MAPK signaling pathway);04064(NF-kappa B signaling pathway);04668(TNF signaling pathway);04071(Sphingolipid signaling pathway);04150(mTOR signaling pathway);04060(Cytokine-cytokine receptor interaction);04210(Apoptosis);04215(Apoptosis - multiple species);04217(Necroptosis);04920(Adipocytokine signaling pathway);04380(Osteoclast differentiation);05010(Alzheimer's disease);05014(Amyotrophic lateral sclerosis (ALS));05418(Fluid shear stress and atherosclerosis);04932(Non-alcoholic fatty liver disease (NAFLD));04931(Insulin resistance);05152(Tuberculosis);05166(HTLV-I infection);05164(Influenza A);05160(Hepatitis C);05168(Herpes simplex infection);05167(Kaposi's sarcoma-associated herpesvirus infection);05165(Human papillomavirus infection);05145(Toxoplasmosis);05142(Chagas disease (American trypanosomiasis));05142(Chagas disease (American trypanosomiasis))","K03158","NA","TNF receptor superfamily member 1A [Source:HGNC Symbol;Acc:HGNC:11916]",{"v":28.8562580946317,"d":"28.86"},{"v":66.4006440626717,"d":"66.40"},{"v":0.434577984927314,"d":"0.43"},{"v":-1.20231300329651,"d":"-1.20"},{"v":0.0759481985098558,"d":"0.08"},{"v":0.777736983611489,"d":"0.78"},"down","no"]
["MSTRG.8313","FCGRT","ENST00000426395;ENST00000221466;ENST00000595881;ENST00000452439;ENST00000599988;ENST00000593431;ENST00000593381;ENST00000598927;ENST00000600273;ENST00000598076;ENST00000599701;ENST00000598319;ENST00000598936;ENST00000596975;ENST00000596147;ENST00000594823;ENST00000595677","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0030881(beta-2-microglobulin binding);GO:0005886(plasma membrane);GO:0019864(IgG binding);GO:0019770(IgG receptor activity);GO:0002416(IgG immunoglobulin transcytosis in epithelial cells mediated by FcRn immunoglobulin receptor);GO:0038094(Fc-gamma receptor signaling pathway);GO:0038094(Fc-gamma receptor signaling pathway)","NA","NA","NA","Fc fragment of IgG receptor and transporter [Source:HGNC Symbol;Acc:HGNC:3621]",{"v":11.2295986966211,"d":"11.23"},{"v":25.8650435132998,"d":"25.87"},{"v":0.434161214182642,"d":"0.43"},{"v":-1.20369724642326,"d":"-1.20"},{"v":0.0759523910253372,"d":"0.08"},{"v":0.777736983611489,"d":"0.78"},"down","no"]
["MSTRG.9395","METTL21A","ENST00000411432;ENST00000448823;ENST00000432416;ENST00000458426;ENST00000406927;ENST00000425132;ENST00000477919;ENST00000471128;ENST00000426075;ENST00000272839","GO:0005737(cytoplasm);GO:0008168(methyltransferase activity);GO:0016740(transferase activity);GO:0032259(methylation);GO:0005515(protein binding);GO:0016279(protein-lysine N-methyltransferase activity);GO:0005654(nucleoplasm);GO:0043234(protein complex);GO:0051117(ATPase binding);GO:0030544(Hsp70 protein binding);GO:0006479(protein methylation);GO:0031072(heat shock protein binding);GO:0008276(protein methyltransferase activity);GO:0018022(peptidyl-lysine methylation);GO:0018022(peptidyl-lysine methylation)","NA","NA","NA","methyltransferase like 21A [Source:HGNC Symbol;Acc:HGNC:30476]",{"v":0.787106684024713,"d":"0.79"},{"v":0.344354446601942,"d":"0.34"},{"v":2.28574566639638,"d":"2.29"},{"v":1.1926648846365,"d":"1.19"},{"v":0.0760431861985209,"d":"0.08"},{"v":0.778005138659804,"d":"0.78"},"up","no"]
["ENSG00000185800","DMWD","ENST00000377735;ENST00000537879;ENST00000601370;ENST00000598237;ENST00000602829;ENST00000602469;ENST00000270223","GO:0003674(molecular_function);GO:0005575(cellular_component);GO:0016579(protein deubiquitination);GO:0016579(protein deubiquitination)","NA","NA","NA","DM1 locus, WD repeat containing [Source:HGNC Symbol;Acc:HGNC:2936]",{"v":0.398500339342524,"d":"0.40"},{"v":0.947804844291269,"d":"0.95"},{"v":0.420445560858582,"d":"0.42"},{"v":-1.25000908195448,"d":"-1.25"},{"v":0.076222924383621,"d":"0.08"},{"v":0.77851078935632,"d":"0.78"},"down","no"]
["ENSG00000163393","SLC22A15","ENST00000369503;ENST00000369502;ENST00000481127","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0055085(transmembrane transport);GO:0006811(ion transport);GO:0022857(transmembrane transporter activity);GO:0015711(organic anion transport);GO:0008514(organic anion transmembrane transporter activity);GO:0008514(organic anion transmembrane transporter activity)","NA","NA","NA","solute carrier family 22 member 15 [Source:HGNC Symbol;Acc:HGNC:20301]",{"v":0.828532711640212,"d":"0.83"},{"v":1.93437118102797,"d":"1.93"},{"v":0.428321471993762,"d":"0.43"},{"v":-1.22323409274025,"d":"-1.22"},{"v":0.0762538645249393,"d":"0.08"},{"v":0.77851078935632,"d":"0.78"},"down","no"]
["MSTRG.4324","PPP2R3C","ENST00000553273;ENST00000554222;ENST00000554899;ENST00000555614;ENST00000557074;ENST00000554563;ENST00000557288;ENST00000554488;ENST00000554265;ENST00000261475;ENST00000554361;ENST00000557278;ENST00000557773;ENST00000557217;ENST00000555726;ENST00000555644;ENST00000556254;ENST00000553282;ENST00000555219","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005794(Golgi apparatus);GO:0046872(metal ion binding);GO:0005829(cytosol);GO:0005515(protein binding);GO:0005813(centrosome);GO:0001782(B cell homeostasis);GO:0000226(microtubule cytoskeleton organization);GO:0005819(spindle);GO:0002759(regulation of antimicrobial humoral response);GO:0030865(cortical cytoskeleton organization);GO:0032147(activation of protein kinase activity);GO:0043029(T cell homeostasis);GO:0045579(positive regulation of B cell differentiation);GO:0048536(spleen development);GO:0050864(regulation of B cell activation);GO:0051900(regulation of mitochondrial depolarization);GO:0051900(regulation of mitochondrial depolarization)","03015(mRNA surveillance pathway);04071(Sphingolipid signaling pathway);04151(PI3K-Akt signaling pathway);04152(AMPK signaling pathway);04261(Adrenergic signaling in cardiomyocytes);04728(Dopaminergic synapse);05165(Human papillomavirus infection);05165(Human papillomavirus infection)","K11583","NA","protein phosphatase 2 regulatory subunit B''gamma [Source:HGNC Symbol;Acc:HGNC:17485]",{"v":2.00256446155837,"d":"2.00"},{"v":4.64293369557339,"d":"4.64"},{"v":0.431314464703132,"d":"0.43"},{"v":-1.21318799531031,"d":"-1.21"},{"v":0.0762865580003701,"d":"0.08"},{"v":0.77851078935632,"d":"0.78"},"down","no"]
["MSTRG.14378","MTFR1","ENST00000262146;ENST00000424808;ENST00000518352;ENST00000527553;ENST00000518636;ENST00000523158;ENST00000522239;ENST00000520398","GO:0005829(cytosol);GO:0005739(mitochondrion);GO:0005886(plasma membrane);GO:0009060(aerobic respiration);GO:0000266(mitochondrial fission);GO:0007005(mitochondrion organization);GO:0007005(mitochondrion organization)","NA","NA","NA","mitochondrial fission regulator 1 [Source:HGNC Symbol;Acc:HGNC:29510]",{"v":1.21282190213869,"d":"1.21"},{"v":0.533689613955498,"d":"0.53"},{"v":2.27252296170752,"d":"2.27"},{"v":1.18429487156975,"d":"1.18"},{"v":0.0764684206629378,"d":"0.08"},{"v":0.779479625194783,"d":"0.78"},"up","no"]
["MSTRG.6048","DPEP2","ENST00000393847;ENST00000572624;ENST00000572888;ENST00000574316;ENST00000268795;MSTRG.6048.1;ENST00000575203;ENST00000573808;ENST00000575510;ENST00000574865","GO:0016020(membrane);GO:0046872(metal ion binding);GO:0016787(hydrolase activity);GO:0008233(peptidase activity);GO:0006508(proteolysis);GO:0008237(metallopeptidase activity);GO:0008235(metalloexopeptidase activity);GO:0008239(dipeptidyl-peptidase activity);GO:0016805(dipeptidase activity);GO:0031225(anchored component of membrane);GO:0008238(exopeptidase activity);GO:0008238(exopeptidase activity)","NA","NA","NA","dipeptidase 2 [Source:HGNC Symbol;Acc:HGNC:23028]",{"v":7.04949428987993,"d":"7.05"},{"v":16.2301028713551,"d":"16.23"},{"v":0.434346864327136,"d":"0.43"},{"v":-1.20308047254745,"d":"-1.20"},{"v":0.0765109547400958,"d":"0.08"},{"v":0.779479625194783,"d":"0.78"},"down","no"]
["ENSG00000136161","RCBTB2","ENST00000344532;ENST00000544904;ENST00000430805;ENST00000611827;ENST00000544492;ENST00000462703;ENST00000481144","GO:0043547(positive regulation of GTPase activity);GO:0005515(protein binding);GO:0005087(Ran guanyl-nucleotide exchange factor activity);GO:0001669(acrosomal vesicle);GO:0001669(acrosomal vesicle)","NA","NA","NA","RCC1 and BTB domain containing protein 2 [Source:HGNC Symbol;Acc:HGNC:1914]",{"v":2.94331594245416,"d":"2.94"},{"v":6.78446083046545,"d":"6.78"},{"v":0.433831960417145,"d":"0.43"},{"v":-1.2047917545631,"d":"-1.20"},{"v":0.0767750723634956,"d":"0.08"},{"v":0.781509231953689,"d":"0.78"},"down","no"]
["MSTRG.1357","CR1","ENST00000400960;ENST00000367049;ENST00000450439;ENST00000367053;ENST00000534202;ENST00000529814;ENST00000367051;ENST00000530487;ENST00000367052;ENST00000436595;ENST00000367050;ENST00000434033","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0002376(immune system process);GO:0045087(innate immune response);GO:0030449(regulation of complement activation);GO:0005886(plasma membrane);GO:0005887(integral component of plasma membrane);GO:0046718(viral entry into host cell);GO:0070062(extracellular exosome);GO:0016032(viral process);GO:0002430(complement receptor mediated signaling pathway);GO:0043312(neutrophil degranulation);GO:0006958(complement activation, classical pathway);GO:0009986(cell surface);GO:0030667(secretory granule membrane);GO:0001618(virus receptor activity);GO:0101003(ficolin-1-rich granule membrane);GO:0045589(regulation of regulatory T cell differentiation);GO:1900005(positive regulation of serine-type endopeptidase activity);GO:1900004(negative regulation of serine-type endopeptidase activity);GO:0001851(complement component C3b binding);GO:0001855(complement component C4b binding);GO:0001861(complement component C4b receptor activity);GO:0004877(complement component C3b receptor activity);GO:0045957(negative regulation of complement activation, alternative pathway);GO:0045959(negative regulation of complement activation, classical pathway);GO:0045959(negative regulation of complement activation, classical pathway)","04640(Hematopoietic cell lineage);04610(Complement and coagulation cascades);05134(Legionellosis);05152(Tuberculosis);05144(Malaria);05140(Leishmaniasis);05140(Leishmaniasis)","K04011","NA","complement C3b/C4b receptor 1 (Knops blood group) [Source:HGNC Symbol;Acc:HGNC:2334]",{"v":3.07615903044047,"d":"3.08"},{"v":7.06878693519407,"d":"7.07"},{"v":0.435174954153009,"d":"0.44"},{"v":-1.2003325680763,"d":"-1.20"},{"v":0.0769787494796259,"d":"0.08"},{"v":0.782920693609506,"d":"0.78"},"down","no"]
["MSTRG.1996","ABLIM1","MSTRG.1996.1;ENST00000369256;ENST00000428430;ENST00000369253;ENST00000481974;ENST00000533213;ENST00000440467;ENST00000477638;ENST00000485570;ENST00000466400;ENST00000392952;ENST00000392955;ENST00000369266;ENST00000369252","GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0003779(actin binding);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0007010(cytoskeleton organization);GO:0007601(visual perception);GO:0015629(actin cytoskeleton);GO:0009887(animal organ morphogenesis);GO:0030032(lamellipodium assembly);GO:0060271(cilium assembly);GO:0001725(stress fiber);GO:0030027(lamellipodium);GO:0030027(lamellipodium)","04360(Axon guidance);04360(Axon guidance)","K07520","NA","actin binding LIM protein 1 [Source:HGNC Symbol;Acc:HGNC:78]",{"v":8.50505635384615,"d":"8.51"},{"v":3.84337030165912,"d":"3.84"},{"v":2.21291618717422,"d":"2.21"},{"v":1.14594881099528,"d":"1.15"},{"v":0.077143285845045,"d":"0.08"},{"v":0.783609487281132,"d":"0.78"},"up","no"]
["MSTRG.6286","SLC43A2","ENST00000301335;MSTRG.6286.1;ENST00000576769;ENST00000572135;ENST00000572801;ENST00000571376;ENST00000574274;ENST00000576721;ENST00000571650;ENST00000576537;ENST00000574743;ENST00000575944","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0055085(transmembrane transport);GO:0003333(amino acid transmembrane transport);GO:0005886(plasma membrane);GO:0005887(integral component of plasma membrane);GO:1902475(L-alpha-amino acid transmembrane transport);GO:0006865(amino acid transport);GO:0015179(L-amino acid transmembrane transporter activity);GO:0015807(L-amino acid transport);GO:0015171(amino acid transmembrane transporter activity);GO:0015175(neutral amino acid transmembrane transporter activity);GO:0015804(neutral amino acid transport);GO:0015804(neutral amino acid transport)","NA","NA","NA","solute carrier family 43 member 2 [Source:HGNC Symbol;Acc:HGNC:23087]",{"v":2.92187077658578,"d":"2.92"},{"v":6.7104596385696,"d":"6.71"},{"v":0.435420363724683,"d":"0.44"},{"v":-1.19951921387109,"d":"-1.20"},{"v":0.0771766194913987,"d":"0.08"},{"v":0.783609487281132,"d":"0.78"},"down","no"]
["ENSG00000198932","GPRASP1","ENST00000361600;ENST00000537097;ENST00000415986;ENST00000466098","GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005515(protein binding);GO:0008333(endosome to lysosome transport);GO:1990172(G-protein coupled receptor catabolic process);GO:1990172(G-protein coupled receptor catabolic process)","NA","NA","NA","G protein-coupled receptor associated sorting protein 1 [Source:HGNC Symbol;Acc:HGNC:24834]",{"v":2.36087761451104,"d":"2.36"},{"v":1.06148950141956,"d":"1.06"},{"v":2.22411772453121,"d":"2.22"},{"v":1.15323315321537,"d":"1.15"},{"v":0.0774018261147772,"d":"0.08"},{"v":0.784837869809853,"d":"0.78"},"up","no"]
["MSTRG.14542","ZHX1;C8orf76;ZHX1-C8orf76","ENST00000395571;ENST00000297857;ENST00000517516;ENST00000517760;ENST00000276704;ENST00000522477;ENST00000518996;ENST00000522595;ENST00000523726;ENST00000602651;ENST00000480132;ENST00000521310;ENST00000357082","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0005654(nucleoplasm);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0005515(protein binding);GO:0030154(cell differentiation);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0003714(transcription corepressor activity);GO:0045892(negative regulation of transcription, DNA-templated);GO:0046982(protein heterodimerization activity);GO:0046982(protein heterodimerization activity)","NA","NA","NA","zinc fingers and homeoboxes 1 [Source:HGNC Symbol;Acc:HGNC:12871];chromosome 8 open reading frame 76 [Source:HGNC Symbol;Acc:HGNC:25924];ZHX1-C8orf76 readthrough [Source:HGNC Symbol;Acc:HGNC:42975]",{"v":0.704658625607951,"d":"0.70"},{"v":1.63144171378727,"d":"1.63"},{"v":0.431923874235224,"d":"0.43"},{"v":-1.21115103236226,"d":"-1.21"},{"v":0.0774680152347251,"d":"0.08"},{"v":0.784837869809853,"d":"0.78"},"down","no"]
["ENSG00000169224","GCSAML","ENST00000536561;ENST00000531662;ENST00000366488;ENST00000463359","GO:0050855(regulation of B cell receptor signaling pathway);GO:2000401(regulation of lymphocyte migration);GO:2000401(regulation of lymphocyte migration)","NA","NA","NA","germinal center associated signaling and motility like [Source:HGNC Symbol;Acc:HGNC:29583]",{"v":0.353260486752137,"d":"0.35"},{"v":0.830328423076923,"d":"0.83"},{"v":0.425446699082118,"d":"0.43"},{"v":-1.23294969572963,"d":"-1.23"},{"v":0.0774931263248559,"d":"0.08"},{"v":0.784837869809853,"d":"0.78"},"down","no"]
["MSTRG.1350","IL24","ENST00000367093;ENST00000367095;ENST00000611909","GO:0005515(protein binding);GO:0005576(extracellular region);GO:0006915(apoptotic process);GO:0005125(cytokine activity);GO:0005615(extracellular space);GO:0008284(positive regulation of cell proliferation);GO:0008285(negative regulation of cell proliferation);GO:0030336(negative regulation of cell migration);GO:0042060(wound healing);GO:0042501(serine phosphorylation of STAT protein);GO:0042531(positive regulation of tyrosine phosphorylation of STAT protein);GO:0071222(cellular response to lipopolysaccharide);GO:0071353(cellular response to interleukin-4);GO:0071353(cellular response to interleukin-4)","04630(Jak-STAT signaling pathway);04060(Cytokine-cytokine receptor interaction);04060(Cytokine-cytokine receptor interaction)","K05444","NA","interleukin 24 [Source:HGNC Symbol;Acc:HGNC:11346]",{"v":13.45699504952,"d":"13.46"},{"v":6.07007329358262,"d":"6.07"},{"v":2.21694111399725,"d":"2.22"},{"v":1.14857045010039,"d":"1.15"},{"v":0.0776114433310945,"d":"0.08"},{"v":0.785229621625117,"d":"0.79"},"up","no"]
["ENSG00000116396","KCNC4","ENST00000459877;ENST00000369787;ENST00000636402;ENST00000469655","GO:0005249(voltage-gated potassium channel activity);GO:0006813(potassium ion transport);GO:0008076(voltage-gated potassium channel complex);GO:0071805(potassium ion transmembrane transport);GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0055085(transmembrane transport);GO:0005216(ion channel activity);GO:0006811(ion transport);GO:0005244(voltage-gated ion channel activity);GO:0005267(potassium channel activity);GO:0034765(regulation of ion transmembrane transport);GO:0051260(protein homooligomerization);GO:0005886(plasma membrane);GO:0007268(chemical synaptic transmission);GO:0046928(regulation of neurotransmitter secretion);GO:0031594(neuromuscular junction);GO:0043679(axon terminus);GO:0043679(axon terminus)","NA","NA","NA","potassium voltage-gated channel subfamily C member 4 [Source:HGNC Symbol;Acc:HGNC:6236]",{"v":0.0694661493091606,"d":"0.07"},{"v":0.0300798952959029,"d":"0.03"},{"v":2.30938800237853,"d":"2.31"},{"v":1.20751058198213,"d":"1.21"},{"v":0.0776802318260375,"d":"0.08"},{"v":0.785229621625117,"d":"0.79"},"up","no"]
["MSTRG.9002","EIF5B","ENST00000289371;ENST00000470023;ENST00000470868;ENST00000494190;ENST00000617677","GO:0003723(RNA binding);GO:0005737(cytoplasm);GO:0003743(translation initiation factor activity);GO:0006412(translation);GO:0006413(translational initiation);GO:0006446(regulation of translational initiation);GO:0005525(GTP binding);GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0016787(hydrolase activity);GO:0003924(GTPase activity);GO:0005515(protein binding);GO:0005829(cytosol);GO:0005829(cytosol)","03013(RNA transport);03013(RNA transport)","K03243","NA","eukaryotic translation initiation factor 5B [Source:HGNC Symbol;Acc:HGNC:30793]",{"v":7.94508602676646,"d":"7.95"},{"v":3.59811525789674,"d":"3.60"},{"v":2.20812438104351,"d":"2.21"},{"v":1.14282143971601,"d":"1.14"},{"v":0.0777876789225538,"d":"0.08"},{"v":0.785229621625117,"d":"0.79"},"up","no"]
["ENSG00000067840","PDZD4","ENST00000164640;ENST00000544474;ENST00000393758;ENST00000483693;ENST00000480418;ENST00000484792","GO:0005737(cytoplasm);GO:0005938(cell cortex);GO:0005515(protein binding);GO:0005515(protein binding)","NA","NA","NA","PDZ domain containing 4 [Source:HGNC Symbol;Acc:HGNC:21167]",{"v":3.47634663671965,"d":"3.48"},{"v":1.56281439691315,"d":"1.56"},{"v":2.22441426415452,"d":"2.22"},{"v":1.15342549363045,"d":"1.15"},{"v":0.0778223937170905,"d":"0.08"},{"v":0.785229621625117,"d":"0.79"},"up","no"]
["MSTRG.4618","TC2N;CATSPERB","ENST00000360594;ENST00000435962;ENST00000556018;ENST00000256343;MSTRG.4618.14;ENST00000555302;ENST00000553676;ENST00000556590;ENST00000557036;ENST00000340892;ENST00000554424","GO:0005634(nucleus);GO:0005886(plasma membrane);GO:0003674(molecular_function);GO:0005575(cellular_component);GO:0010468(regulation of gene expression);GO:0030193(regulation of blood coagulation);GO:0036128(CatSper complex);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0007275(multicellular organism development);GO:0030154(cell differentiation);GO:0007283(spermatogenesis);GO:0035036(sperm-egg recognition);GO:0005929(cilium);GO:0048240(sperm capacitation);GO:0032570(response to progesterone);GO:0030193(regulation of blood coagulation)","NA","NA","NA","tandem C2 domains, nuclear [Source:HGNC Symbol;Acc:HGNC:19859];cation channel sperm associated auxiliary subunit beta [Source:HGNC Symbol;Acc:HGNC:20500]",{"v":5.38594359376597,"d":"5.39"},{"v":2.43874929006983,"d":"2.44"},{"v":2.20848597094282,"d":"2.21"},{"v":1.14305766791553,"d":"1.14"},{"v":0.0779252397880618,"d":"0.08"},{"v":0.785229621625117,"d":"0.79"},"up","no"]
["ENSG00000152464","RPP38","ENST00000378203;ENST00000378197;ENST00000441850;ENST00000616640;ENST00000378202;ENST00000378201","GO:0005634(nucleus);GO:0005730(nucleolus);GO:0008033(tRNA processing);GO:0016787(hydrolase activity);GO:0001650(fibrillar center);GO:0005515(protein binding);GO:0090501(RNA phosphodiester bond hydrolysis);GO:0090502(RNA phosphodiester bond hydrolysis, endonucleolytic);GO:0005654(nucleoplasm);GO:0006364(rRNA processing);GO:0004526(ribonuclease P activity);GO:0001682(tRNA 5'-leader removal);GO:0005655(nucleolar ribonuclease P complex);GO:0005655(nucleolar ribonuclease P complex)","03013(RNA transport);03008(Ribosome biogenesis in eukaryotes);03008(Ribosome biogenesis in eukaryotes)","K14523","EC:3.1.26.5","ribonuclease P/MRP subunit p38 [Source:HGNC Symbol;Acc:HGNC:30329]",{"v":2.15316222901554,"d":"2.15"},{"v":0.944307542487047,"d":"0.94"},{"v":2.28014934980261,"d":"2.28"},{"v":1.18912832402287,"d":"1.19"},{"v":0.0779752523819059,"d":"0.08"},{"v":0.785229621625117,"d":"0.79"},"up","no"]
["MSTRG.6901","CCDC43","ENST00000315286;ENST00000588210;ENST00000592333;ENST00000457422;ENST00000588687","GO:0005515(protein binding);GO:0005515(protein binding)","NA","NA","NA","coiled-coil domain containing 43 [Source:HGNC Symbol;Acc:HGNC:26472]",{"v":3.31211630262697,"d":"3.31"},{"v":1.48064633345009,"d":"1.48"},{"v":2.23693952282942,"d":"2.24"},{"v":1.16152625268961,"d":"1.16"},{"v":0.0779882600451453,"d":"0.08"},{"v":0.785229621625117,"d":"0.79"},"up","no"]
["ENSG00000117174","ZNHIT6","ENST00000370574;ENST00000431532","GO:0046872(metal ion binding);GO:0005515(protein binding);GO:0042254(ribosome biogenesis);GO:0070062(extracellular exosome);GO:0019899(enzyme binding);GO:0051259(protein oligomerization);GO:0070761(pre-snoRNP complex);GO:0042802(identical protein binding);GO:0051117(ATPase binding);GO:0001094(TFIID-class transcription factor binding);GO:0048254(snoRNA localization);GO:0000492(box C/D snoRNP assembly);GO:0000492(box C/D snoRNP assembly)","NA","NA","NA","zinc finger HIT-type containing 6 [Source:HGNC Symbol;Acc:HGNC:26089]",{"v":0.492368588349201,"d":"0.49"},{"v":1.13991917589156,"d":"1.14"},{"v":0.431932893807236,"d":"0.43"},{"v":-1.21112090585913,"d":"-1.21"},{"v":0.0781265178135757,"d":"0.08"},{"v":0.785964517553115,"d":"0.79"},"down","no"]
["MSTRG.8169","AC243960.1;CEACAM21","ENST00000601116;ENST00000407170;ENST00000595395;ENST00000457737;ENST00000482870;ENST00000595649;ENST00000618577;ENST00000632983;ENST00000187608;ENST00000401445","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016021(integral component of membrane)","NA","NA","NA","carcinoembryonic antigen related cell adhesion molecule 21 [Source:HGNC Symbol;Acc:HGNC:28834]",{"v":4.20846859329576,"d":"4.21"},{"v":1.89558849955503,"d":"1.90"},{"v":2.22013828121644,"d":"2.22"},{"v":1.15064953757188,"d":"1.15"},{"v":0.0784647972686065,"d":"0.08"},{"v":0.787708640276098,"d":"0.79"},"up","no"]
["MSTRG.8074","TMEM147-AS1","ENST00000588286;ENST00000590717;ENST00000590125","NA","NA","NA","NA","TMEM147 antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:51273]",{"v":0.824996621115456,"d":"0.82"},{"v":0.364527763325787,"d":"0.36"},{"v":2.26319283225113,"d":"2.26"},{"v":1.1783595127004,"d":"1.18"},{"v":0.0785344468982967,"d":"0.08"},{"v":0.787708640276098,"d":"0.79"},"up","no"]
["MSTRG.1160","FCGR3B;FCGR3A","ENST00000531221;MSTRG.1160.5;ENST00000421702;ENST00000426740;ENST00000436743;ENST00000443193;ENST00000367969;ENST00000367964;ENST00000367967;MSTRG.1160.1;MSTRG.1160.2;ENST00000294800;ENST00000614870;ENST00000638849;ENST00000476031;MSTRG.1160.6;ENST00000442336;ENST00000534489;MSTRG.1160.3;ENST00000534776;ENST00000533780;ENST00000613418;MSTRG.1160.4","GO:0016020(membrane);GO:0005886(plasma membrane);GO:0005576(extracellular region);GO:0031225(anchored component of membrane);GO:0070062(extracellular exosome);GO:0006501(C-terminal protein lipidation);GO:0043312(neutrophil degranulation);GO:0006955(immune response);GO:0030667(secretory granule membrane);GO:0019864(IgG binding);GO:0016021(integral component of membrane);GO:0038096(Fc-gamma receptor signaling pathway involved in phagocytosis);GO:0050776(regulation of immune response);GO:0009897(external side of plasma membrane);GO:0016021(integral component of membrane)","04145(Phagosome);04650(Natural killer cell mediated cytotoxicity);04380(Osteoclast differentiation);05322(Systemic lupus erythematosus);05150(Staphylococcus aureus infection);05152(Tuberculosis);05140(Leishmaniasis);04666(Fc gamma R-mediated phagocytosis);05140(Leishmaniasis)","K06463","NA","Fc fragment of IgG receptor IIIb [Source:HGNC Symbol;Acc:HGNC:3620];Fc fragment of IgG receptor IIIa [Source:HGNC Symbol;Acc:HGNC:3619]",{"v":94.2365373383265,"d":"94.24"},{"v":215.106174602512,"d":"215.11"},{"v":0.438093130113365,"d":"0.44"},{"v":-1.1906905034383,"d":"-1.19"},{"v":0.0786136165195347,"d":"0.08"},{"v":0.787708640276098,"d":"0.79"},"down","no"]
["ENSG00000122591","FAM126A","ENST00000432176;ENST00000467005;ENST00000465661;ENST00000440481;ENST00000409763;ENST00000421730","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0004871(signal transducer activity);GO:0007165(signal transduction);GO:0005515(protein binding);GO:0090002(establishment of protein localization to plasma membrane);GO:0042552(myelination);GO:0046854(phosphatidylinositol phosphorylation);GO:0043005(neuron projection);GO:0043005(neuron projection)","NA","NA","NA","family with sequence similarity 126 member A [Source:HGNC Symbol;Acc:HGNC:24587]",{"v":0.41045719139251,"d":"0.41"},{"v":0.946972596799779,"d":"0.95"},{"v":0.433441466817116,"d":"0.43"},{"v":-1.20609091397612,"d":"-1.21"},{"v":0.078614813436304,"d":"0.08"},{"v":0.787708640276098,"d":"0.79"},"down","no"]
["MSTRG.13452","LFNG","ENST00000222725;ENST00000402045;ENST00000614382;ENST00000359574;ENST00000402506;ENST00000493850","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0046872(metal ion binding);GO:0016740(transferase activity);GO:0016757(transferase activity, transferring glycosyl groups);GO:0005794(Golgi apparatus);GO:0005576(extracellular region);GO:0000139(Golgi membrane);GO:0007275(multicellular organism development);GO:0003674(molecular_function);GO:0030217(T cell differentiation);GO:0001756(somitogenesis);GO:0002315(marginal zone B cell differentiation);GO:0014807(regulation of somitogenesis);GO:1903561(extracellular vesicle);GO:0033829(O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity);GO:0007389(pattern specification process);GO:0030173(integral component of Golgi membrane);GO:0009887(animal organ morphogenesis);GO:0008593(regulation of Notch signaling pathway);GO:1902367(negative regulation of Notch signaling pathway involved in somitogenesis);GO:0001541(ovarian follicle development);GO:0007386(compartment pattern specification);GO:0032092(positive regulation of protein binding);GO:0045747(positive regulation of Notch signaling pathway);GO:0051446(positive regulation of meiotic cell cycle);GO:0051446(positive regulation of meiotic cell cycle)","00514(Other types of O-glycan biosynthesis);04330(Notch signaling pathway);05165(Human papillomavirus infection);05165(Human papillomavirus infection)","K05948","EC:2.4.1.222","LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase [Source:HGNC Symbol;Acc:HGNC:6560]",{"v":16.3136237847324,"d":"16.31"},{"v":7.39328859666569,"d":"7.39"},{"v":2.20654497270534,"d":"2.21"},{"v":1.1417891519084,"d":"1.14"},{"v":0.0786475632237127,"d":"0.08"},{"v":0.787708640276098,"d":"0.79"},"up","no"]
["MSTRG.11464","PCYT1A;TCTEX1D2;TM4SF19","ENST00000431016;ENST00000411591;ENST00000412869;ENST00000465757;ENST00000460677;ENST00000419333;ENST00000441879;ENST00000491186;ENST00000273695;ENST00000443555;ENST00000433733;ENST00000460827;ENST00000473978;ENST00000454715;ENST00000325318;ENST00000446494;ENST00000426563;ENST00000292823;ENST00000430755;ENST00000488235;ENST00000446879;ENST00000438634","GO:0003824(catalytic activity);GO:0009058(biosynthetic process);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0016740(transferase activity);GO:0006629(lipid metabolic process);GO:0005829(cytosol);GO:0005789(endoplasmic reticulum membrane);GO:0008654(phospholipid biosynthetic process);GO:0016779(nucleotidyltransferase activity);GO:0006656(phosphatidylcholine biosynthetic process);GO:0004105(choline-phosphate cytidylyltransferase activity);GO:0005516(calmodulin binding);GO:0008289(lipid binding);GO:0031210(phosphatidylcholine binding);GO:0042803(protein homodimerization activity);GO:0006657(CDP-choline pathway);GO:0005635(nuclear envelope);GO:0005783(endoplasmic reticulum);GO:0005886(plasma membrane);GO:0042587(glycogen granule);GO:0006952(defense response);GO:0005515(protein binding);GO:0005813(centrosome);GO:0060271(cilium assembly);GO:0005868(cytoplasmic dynein complex);GO:0000922(spindle pole);GO:0045505(dynein intermediate chain binding);GO:0005930(axoneme);GO:0031021(interphase microtubule organizing center);GO:0097546(ciliary base);GO:1902017(regulation of cilium assembly);GO:1905799(regulation of intraciliary retrograde transport);GO:0016021(integral component of membrane);GO:0006952(defense response)","00564(Glycerophospholipid metabolism);00440(Phosphonate and phosphinate metabolism);05231(Choline metabolism in cancer);05231(Choline metabolism in cancer)","K00968","EC:2.7.7.15","phosphate cytidylyltransferase 1, choline, alpha [Source:HGNC Symbol;Acc:HGNC:8754];Tctex1 domain containing 2 [Source:HGNC Symbol;Acc:HGNC:28482];transmembrane 4 L six family member 19 [Source:HGNC Symbol;Acc:HGNC:25167]",{"v":3.35783214004848,"d":"3.36"},{"v":1.51854618700063,"d":"1.52"},{"v":2.2112150218366,"d":"2.21"},{"v":1.14483932178651,"d":"1.14"},{"v":0.0787125384723291,"d":"0.08"},{"v":0.787708640276098,"d":"0.79"},"up","no"]
["ENSG00000151692","RNF144A","ENST00000320892;ENST00000467276;ENST00000480970","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0043231(intracellular membrane-bounded organelle);GO:0046872(metal ion binding);GO:0016740(transferase activity);GO:0016567(protein ubiquitination);GO:0005794(Golgi apparatus);GO:0004842(ubiquitin-protein transferase activity);GO:0005886(plasma membrane);GO:0030659(cytoplasmic vesicle membrane);GO:0031410(cytoplasmic vesicle);GO:0000151(ubiquitin ligase complex);GO:0061630(ubiquitin protein ligase activity);GO:0010008(endosome membrane);GO:0042787(protein ubiquitination involved in ubiquitin-dependent protein catabolic process);GO:0000209(protein polyubiquitination);GO:0032436(positive regulation of proteasomal ubiquitin-dependent protein catabolic process);GO:0031624(ubiquitin conjugating enzyme binding);GO:0031624(ubiquitin conjugating enzyme binding)","NA","NA","NA","ring finger protein 144A [Source:HGNC Symbol;Acc:HGNC:20457]",{"v":3.37605976904063,"d":"3.38"},{"v":1.52744394840105,"d":"1.53"},{"v":2.21026753392472,"d":"2.21"},{"v":1.14422100604492,"d":"1.14"},{"v":0.0787966353599071,"d":"0.08"},{"v":0.787708640276098,"d":"0.79"},"up","no"]
["MSTRG.8782","ARHGAP25","ENST00000409220;ENST00000409030;ENST00000409202;ENST00000488795;ENST00000485573;ENST00000463483;ENST00000467265;ENST00000473986;ENST00000485700;ENST00000497259;ENST00000456116;ENST00000481684;ENST00000497079;ENST00000479844","GO:0007165(signal transduction);GO:0043547(positive regulation of GTPase activity);GO:0005096(GTPase activator activity);GO:0005829(cytosol);GO:0051056(regulation of small GTPase mediated signal transduction);GO:0051056(regulation of small GTPase mediated signal transduction)","NA","NA","NA","Rho GTPase activating protein 25 [Source:HGNC Symbol;Acc:HGNC:28951]",{"v":18.1378719361702,"d":"18.14"},{"v":41.4055893741746,"d":"41.41"},{"v":0.438053707490108,"d":"0.44"},{"v":-1.19082033287024,"d":"-1.19"},{"v":0.078841027708016,"d":"0.08"},{"v":0.787708640276098,"d":"0.79"},"down","no"]
["MSTRG.529","IPP;AL604028.1","ENST00000396478;ENST00000359942;ENST00000495072;ENST00000430643;ENST00000461718","GO:0005737(cytoplasm);GO:0003779(actin binding);GO:0016567(protein ubiquitination);GO:0005856(cytoskeleton);GO:0004842(ubiquitin-protein transferase activity);GO:0031463(Cul3-RING ubiquitin ligase complex);GO:0015629(actin cytoskeleton);GO:0015629(actin cytoskeleton)","NA","NA","NA","intracisternal A particle-promoted polypeptide [Source:HGNC Symbol;Acc:HGNC:6108]",{"v":1.01943643233784,"d":"1.02"},{"v":0.454759623191787,"d":"0.45"},{"v":2.24170392521394,"d":"2.24"},{"v":1.164595745658,"d":"1.16"},{"v":0.0789098029865961,"d":"0.08"},{"v":0.787708640276098,"d":"0.79"},"up","no"]
["ENSG00000143013","LMO4","ENST00000489303;ENST00000370544;ENST00000495705;ENST00000370542","GO:0046872(metal ion binding);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0005515(protein binding);GO:0031252(cell leading edge);GO:0006366(transcription from RNA polymerase II promoter);GO:0030334(regulation of cell migration);GO:0008134(transcription factor binding);GO:0001843(neural tube closure);GO:0005667(transcription factor complex);GO:0033674(positive regulation of kinase activity);GO:0001158(enhancer sequence-specific DNA binding);GO:0003281(ventricular septum development);GO:0021514(ventral spinal cord interneuron differentiation);GO:0021522(spinal cord motor neuron differentiation);GO:0021527(spinal cord association neuron differentiation);GO:0031333(negative regulation of protein complex assembly);GO:0042659(regulation of cell fate specification);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0048538(thymus development);GO:0050865(regulation of cell activation);GO:0050865(regulation of cell activation)","NA","NA","NA","LIM domain only 4 [Source:HGNC Symbol;Acc:HGNC:6644]",{"v":1.05802943099606,"d":"1.06"},{"v":2.43154320572604,"d":"2.43"},{"v":0.435126724667901,"d":"0.44"},{"v":-1.20049246766228,"d":"-1.20"},{"v":0.0789540216586323,"d":"0.08"},{"v":0.787708640276098,"d":"0.79"},"down","no"]
["ENSG00000102547","CAB39L","ENST00000610540;ENST00000409082;ENST00000476943;ENST00000409308","GO:0005515(protein binding);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0007050(cell cycle arrest);GO:0007050(cell cycle arrest)","04152(AMPK signaling pathway);04150(mTOR signaling pathway);04150(mTOR signaling pathway)","K08272","NA","calcium binding protein 39 like [Source:HGNC Symbol;Acc:HGNC:20290]",{"v":0.240683942469037,"d":"0.24"},{"v":0.576146433080304,"d":"0.58"},{"v":0.417747865212402,"d":"0.42"},{"v":-1.25929563908528,"d":"-1.26"},{"v":0.0790633196785478,"d":"0.08"},{"v":0.788146105603537,"d":"0.79"},"down","no"]
["ENSG00000144199","FAHD2B","ENST00000414820;ENST00000474849;ENST00000272610;ENST00000468548;ENST00000483657;ENST00000463096","GO:0046872(metal ion binding);GO:0016787(hydrolase activity);GO:0003824(catalytic activity);GO:0008152(metabolic process);GO:0008152(metabolic process)","NA","NA","NA","fumarylacetoacetate hydrolase domain containing 2B [Source:HGNC Symbol;Acc:HGNC:25318]",{"v":0.931092249060857,"d":"0.93"},{"v":0.403757201728024,"d":"0.40"},{"v":2.3060696999977,"d":"2.31"},{"v":1.20543611850633,"d":"1.21"},{"v":0.0792858249370706,"d":"0.08"},{"v":0.788961829874405,"d":"0.79"},"up","no"]
["ENSG00000048392","RRM2B","ENST00000251810;ENST00000519125;ENST00000523957;ENST00000621845;ENST00000395912;ENST00000522394;ENST00000517517;ENST00000395910;ENST00000522368","GO:0005739(mitochondrion);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0005515(protein binding);GO:0006281(DNA repair);GO:0006974(cellular response to DNA damage stimulus);GO:0006260(DNA replication);GO:0009263(deoxyribonucleotide biosynthetic process);GO:0070062(extracellular exosome);GO:0004748(ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor);GO:0015949(nucleobase-containing small molecule interconversion);GO:0005971(ribonucleoside-diphosphate reductase complex);GO:0001822(kidney development);GO:0003014(renal system process);GO:0006264(mitochondrial DNA replication);GO:0006979(response to oxidative stress);GO:0009200(deoxyribonucleoside triphosphate metabolic process);GO:0014075(response to amine);GO:1902254(negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016021(integral component of membrane)","00230(Purine metabolism);00240(Pyrimidine metabolism);00480(Glutathione metabolism);00983(Drug metabolism - other enzymes);04115(p53 signaling pathway);04115(p53 signaling pathway)","K10808","EC:1.17.4.1","ribonucleotide reductase regulatory TP53 inducible subunit M2B [Source:HGNC Symbol;Acc:HGNC:17296]",{"v":2.73545817591925,"d":"2.74"},{"v":1.23485129470079,"d":"1.23"},{"v":2.21521262329977,"d":"2.22"},{"v":1.14744517998039,"d":"1.15"},{"v":0.0793032568598145,"d":"0.08"},{"v":0.788961829874405,"d":"0.79"},"up","no"]
["MSTRG.1545","GATA3","ENST00000379328;ENST00000346208;ENST00000481743;ENST00000461472","GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0005634(nucleus);GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0005654(nucleoplasm);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0043565(sequence-specific DNA binding);GO:0005515(protein binding);GO:0007165(signal transduction);GO:0003713(transcription coactivator activity);GO:0045893(positive regulation of transcription, DNA-templated);GO:0002376(immune system process);GO:0045087(innate immune response);GO:0003682(chromatin binding);GO:0045582(positive regulation of T cell differentiation);GO:0000976(transcription regulatory region sequence-specific DNA binding);GO:0008285(negative regulation of cell proliferation);GO:0016579(protein deubiquitination);GO:1902036(regulation of hematopoietic stem cell differentiation);GO:0008584(male gonad development);GO:0009615(response to virus);GO:0005667(transcription factor complex);GO:0050728(negative regulation of inflammatory response);GO:0071356(cellular response to tumor necrosis factor);GO:0000977(RNA polymerase II regulatory region sequence-specific DNA binding);GO:0001228(transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding);GO:0032753(positive regulation of interleukin-4 production);GO:2000667(positive regulation of interleukin-13 secretion);GO:0044212(transcription regulatory region DNA binding);GO:0045786(negative regulation of cell cycle);GO:0045892(negative regulation of transcription, DNA-templated);GO:0000790(nuclear chromatin);GO:0006366(transcription from RNA polymerase II promoter);GO:0045599(negative regulation of fat cell differentiation);GO:0014065(phosphatidylinositol 3-kinase signaling);GO:0050852(T cell receptor signaling pathway);GO:0009653(anatomical structure morphogenesis);GO:2000352(negative regulation of endothelial cell apoptotic process);GO:0001709(cell fate determination);GO:0001046(core promoter sequence-specific DNA binding);GO:0070888(E-box binding);GO:0006952(defense response);GO:0043627(response to estrogen);GO:0010595(positive regulation of endothelial cell migration);GO:0051897(positive regulation of protein kinase B signaling);GO:0001078(transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0007596(blood coagulation);GO:0000987(core promoter proximal region sequence-specific DNA binding);GO:0001823(mesonephros development);GO:0060037(pharyngeal system development);GO:0008134(transcription factor binding);GO:0001822(kidney development);GO:0048485(sympathetic nervous system development);GO:2000611(positive regulation of thyroid hormone generation);GO:0071837(HMG box domain binding);GO:0042421(norepinephrine biosynthetic process);GO:2000146(negative regulation of cell motility);GO:0001085(RNA polymerase II transcription factor binding);GO:0035457(cellular response to interferon-alpha);GO:0071353(cellular response to interleukin-4);GO:0060231(mesenchymal to epithelial transition);GO:0031929(TOR signaling);GO:0000979(RNA polymerase II core promoter sequence-specific DNA binding);GO:0001071(nucleic acid binding transcription factor activity);GO:0001077(transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0001158(enhancer sequence-specific DNA binding);GO:0005134(interleukin-2 receptor binding);GO:0046983(protein dimerization activity);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0000902(cell morphogenesis);GO:0001701(in utero embryonic development);GO:0001764(neuron migration);GO:0001775(cell activation);GO:0001806(type IV hypersensitivity);GO:0001819(positive regulation of cytokine production);GO:0002088(lens development in camera-type eye);GO:0002572(pro-T cell differentiation);GO:0003180(aortic valve morphogenesis);GO:0003215(cardiac right ventricle morphogenesis);GO:0003281(ventricular septum development);GO:0006338(chromatin remodeling);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0006959(humoral immune response);GO:0007399(nervous system development);GO:0007411(axon guidance);GO:0009791(post-embryonic development);GO:0009967(positive regulation of signal transduction);GO:0010332(response to gamma radiation);GO:0010628(positive regulation of gene expression);GO:0010629(negative regulation of gene expression);GO:0010975(regulation of neuron projection development);GO:0030182(neuron differentiation);GO:0030217(T cell differentiation);GO:0030218(erythrocyte differentiation);GO:0032689(negative regulation of interferon-gamma production);GO:0032703(negative regulation of interleukin-2 production);GO:0032736(positive regulation of interleukin-13 production);GO:0032754(positive regulation of interleukin-5 production);GO:0033077(T cell differentiation in thymus);GO:0033600(negative regulation of mammary gland epithelial cell proliferation);GO:0035162(embryonic hemopoiesis);GO:0035799(ureter maturation);GO:0035898(parathyroid hormone secretion);GO:0042035(regulation of cytokine biosynthetic process);GO:0042472(inner ear morphogenesis);GO:0042493(response to drug);GO:0043370(regulation of CD4-positive, alpha-beta T cell differentiation);GO:0043523(regulation of neuron apoptotic process);GO:0043583(ear development);GO:0045061(thymic T cell selection);GO:0045064(T-helper 2 cell differentiation);GO:0045471(response to ethanol);GO:0045597(positive regulation of cell differentiation);GO:0048469(cell maturation);GO:0048538(thymus development);GO:0048568(embryonic organ development);GO:0048589(developmental growth);GO:0048646(anatomical structure formation involved in morphogenesis);GO:0048872(homeostasis of number of cells);GO:0051569(regulation of histone H3-K4 methylation);GO:0060017(parathyroid gland development);GO:0060065(uterus development);GO:0060374(mast cell differentiation);GO:0060676(ureteric bud formation);GO:0061085(regulation of histone H3-K27 methylation);GO:0061290(canonical Wnt signaling pathway involved in metanephric kidney development);GO:0071345(cellular response to cytokine stimulus);GO:0071442(positive regulation of histone H3-K14 acetylation);GO:0071599(otic vesicle development);GO:0071773(cellular response to BMP stimulus);GO:0072001(renal system development);GO:0072107(positive regulation of ureteric bud formation);GO:0072178(nephric duct morphogenesis);GO:0072179(nephric duct formation);GO:0072182(regulation of nephron tubule epithelial cell differentiation);GO:0072602(interleukin-4 secretion);GO:0072643(interferon-gamma secretion);GO:0072676(lymphocyte migration);GO:0090102(cochlea development);GO:1901536(negative regulation of DNA demethylation);GO:2000114(regulation of establishment of cell polarity);GO:2000553(positive regulation of T-helper 2 cell cytokine production);GO:2000607(negative regulation of cell proliferation involved in mesonephros development);GO:2000617(positive regulation of histone H3-K9 acetylation);GO:2000664(positive regulation of interleukin-5 secretion);GO:2000679(positive regulation of transcription regulatory region DNA binding);GO:2000683(regulation of cellular response to X-ray);GO:2000703(negative regulation of fibroblast growth factor receptor signaling pathway involved in ureteric bud formation);GO:2000734(negative regulation of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation);GO:2000734(negative regulation of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation)","04658(Th1 and Th2 cell differentiation);04659(Th17 cell differentiation);05321(Inflammatiory bowel disease (IBD));05321(Inflammatiory bowel disease (IBD))","K17895","NA","GATA binding protein 3 [Source:HGNC Symbol;Acc:HGNC:4172]",{"v":12.2294888751921,"d":"12.23"},{"v":5.55320016415616,"d":"5.55"},{"v":2.20224168293607,"d":"2.20"},{"v":1.13897280479699,"d":"1.14"},{"v":0.0793417020410151,"d":"0.08"},{"v":0.788961829874405,"d":"0.79"},"up","no"]
["MSTRG.14508","AZIN1","ENST00000347770;ENST00000337198;ENST00000518940;ENST00000517581;ENST00000522311;ENST00000523071;ENST00000520402;ENST00000518697","GO:0005634(nucleus);GO:0003824(catalytic activity);GO:0043085(positive regulation of catalytic activity);GO:0005515(protein binding);GO:0042978(ornithine decarboxylase activator activity);GO:0006596(polyamine biosynthetic process);GO:1902269(positive regulation of polyamine transmembrane transport);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0006521(regulation of cellular amino acid metabolic process);GO:0042177(negative regulation of protein catabolic process);GO:0033387(putrescine biosynthetic process from ornithine);GO:0033387(putrescine biosynthetic process from ornithine)","NA","NA","NA","antizyme inhibitor 1 [Source:HGNC Symbol;Acc:HGNC:16432]",{"v":3.17844497074385,"d":"3.18"},{"v":7.25039795144725,"d":"7.25"},{"v":0.438382140129205,"d":"0.44"},{"v":-1.18973907138793,"d":"-1.19"},{"v":0.0795041494718604,"d":"0.08"},{"v":0.789456995616001,"d":"0.79"},"down","no"]
["ENSG00000137337","MDC1","ENST00000376406;ENST00000417033;ENST00000492462;ENST00000613547;ENST00000416571;ENST00000494654;ENST00000489540;ENST00000422266","GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005925(focal adhesion);GO:0005694(chromosome);GO:0005515(protein binding);GO:0006281(DNA repair);GO:0006974(cellular response to DNA damage stimulus);GO:0007049(cell cycle);GO:0016604(nuclear body);GO:0008022(protein C-terminus binding);GO:0006303(double-strand break repair via nonhomologous end joining);GO:0031573(intra-S DNA damage checkpoint);GO:0070975(FHA domain binding);GO:0070975(FHA domain binding)","NA","NA","NA","mediator of DNA damage checkpoint 1 [Source:HGNC Symbol;Acc:HGNC:21163]",{"v":5.28197555282738,"d":"5.28"},{"v":2.40261662698413,"d":"2.40"},{"v":2.19842628803312,"d":"2.20"},{"v":1.13647116062794,"d":"1.14"},{"v":0.0795818576975182,"d":"0.08"},{"v":0.789456995616001,"d":"0.79"},"up","no"]
["MSTRG.1246","ARPC5","ENST00000462965;ENST00000359856;ENST00000602490;ENST00000367534;ENST00000294742","GO:0005737(cytoplasm);GO:0003779(actin binding);GO:0015629(actin cytoskeleton);GO:0005856(cytoskeleton);GO:0042995(cell projection);GO:0030833(regulation of actin filament polymerization);GO:0034314(Arp2/3 complex-mediated actin nucleation);GO:0005885(Arp2/3 protein complex);GO:0005925(focal adhesion);GO:0038096(Fc-gamma receptor signaling pathway involved in phagocytosis);GO:0005576(extracellular region);GO:0005515(protein binding);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0061024(membrane organization);GO:0043312(neutrophil degranulation);GO:0034774(secretory granule lumen);GO:1904813(ficolin-1-rich granule lumen);GO:0005200(structural constituent of cytoskeleton);GO:0006928(movement of cell or subcellular component);GO:0048013(ephrin receptor signaling pathway);GO:0030036(actin cytoskeleton organization);GO:0051015(actin filament binding);GO:0016477(cell migration);GO:0014909(smooth muscle cell migration);GO:0021769(orbitofrontal cortex development);GO:0030011(maintenance of cell polarity);GO:0051639(actin filament network formation);GO:0061842(microtubule organizing center localization);GO:0097581(lamellipodium organization);GO:0005768(endosome);GO:0030027(lamellipodium);GO:0030426(growth cone);GO:0043005(neuron projection);GO:0043005(neuron projection)","04144(Endocytosis);04810(Regulation of actin cytoskeleton);04666(Fc gamma R-mediated phagocytosis);05130(Pathogenic Escherichia coli infection);05132(Salmonella infection);05131(Shigellosis);05100(Bacterial invasion of epithelial cells);05100(Bacterial invasion of epithelial cells)","K05754","NA","actin related protein 2/3 complex subunit 5 [Source:HGNC Symbol;Acc:HGNC:708]",{"v":5.08697502390813,"d":"5.09"},{"v":11.5923513430911,"d":"11.59"},{"v":0.438821674167071,"d":"0.44"},{"v":-1.18829331016468,"d":"-1.19"},{"v":0.0795881741137539,"d":"0.08"},{"v":0.789456995616001,"d":"0.79"},"down","no"]
["ENSG00000146776","ATXN7L1","ENST00000419735;ENST00000472195;ENST00000477775;ENST00000478915;ENST00000318724;ENST00000485652;ENST00000472910;ENST00000464874;ENST00000474433;ENST00000481880;ENST00000484475","GO:0005515(protein binding);GO:0005515(protein binding)","NA","NA","NA","ataxin 7 like 1 [Source:HGNC Symbol;Acc:HGNC:22210]",{"v":2.39385606425558,"d":"2.39"},{"v":1.08192973658831,"d":"1.08"},{"v":2.21257997012284,"d":"2.21"},{"v":1.14572960001581,"d":"1.15"},{"v":0.0796642984581405,"d":"0.08"},{"v":0.789561713607348,"d":"0.79"},"up","no"]
["ENSG00000221817","PPP3CB-AS1","ENST00000442133;ENST00000620432;ENST00000600887;ENST00000610317;ENST00000593790;ENST00000595935;ENST00000620559;ENST00000422977;ENST00000439792;ENST00000596320;ENST00000600607;ENST00000600206","NA","NA","NA","NA","PPP3CB antisense RNA 1 (head to head) [Source:HGNC Symbol;Acc:HGNC:50750]",{"v":1.75474663372604,"d":"1.75"},{"v":0.793265530508177,"d":"0.79"},{"v":2.21205455958981,"d":"2.21"},{"v":1.14538696960468,"d":"1.15"},{"v":0.0798784172438523,"d":"0.08"},{"v":0.790413642813808,"d":"0.79"},"up","no"]
["MSTRG.3276","MRPS35","ENST00000081029;ENST00000538315","GO:0003723(RNA binding);GO:0030529(intracellular ribonucleoprotein complex);GO:0005840(ribosome);GO:0005739(mitochondrion);GO:0003735(structural constituent of ribosome);GO:0005763(mitochondrial small ribosomal subunit);GO:0005743(mitochondrial inner membrane);GO:0070125(mitochondrial translational elongation);GO:0070126(mitochondrial translational termination);GO:0042769(DNA damage response, detection of DNA damage);GO:0042769(DNA damage response, detection of DNA damage)","NA","NA","NA","mitochondrial ribosomal protein S35 [Source:HGNC Symbol;Acc:HGNC:16635]",{"v":2.84654971601819,"d":"2.85"},{"v":6.52063110661951,"d":"6.52"},{"v":0.436545124156537,"d":"0.44"},{"v":-1.19579730693839,"d":"-1.20"},{"v":0.0799871126065668,"d":"0.08"},{"v":0.790413642813808,"d":"0.79"},"down","no"]
["ENSG00000196267","ZNF836","ENST00000597252;ENST00000597065;ENST00000599618","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0005622(intracellular);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding)","NA","NA","NA","zinc finger protein 836 [Source:HGNC Symbol;Acc:HGNC:34333]",{"v":0.718847661639962,"d":"0.72"},{"v":1.65717600683318,"d":"1.66"},{"v":0.433778704661348,"d":"0.43"},{"v":-1.20496886583657,"d":"-1.20"},{"v":0.0799929967576961,"d":"0.08"},{"v":0.790413642813808,"d":"0.79"},"down","no"]
["ENSG00000258301","VASH1-AS1","ENST00000556072;ENST00000554058","NA","NA","NA","NA","VASH1 antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:53215]",{"v":0.937498437873033,"d":"0.94"},{"v":0.410952651112317,"d":"0.41"},{"v":2.28128090994309,"d":"2.28"},{"v":1.18984410663651,"d":"1.19"},{"v":0.0800786048001509,"d":"0.08"},{"v":0.790413642813808,"d":"0.79"},"up","no"]
["ENSG00000125967","NECAB3","ENST00000488489;ENST00000473892;ENST00000607055;ENST00000606699;ENST00000439478;ENST00000606525;ENST00000606106;ENST00000480994;ENST00000485399;ENST00000375238;ENST00000463246;ENST00000485976;ENST00000246190;ENST00000484824","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005794(Golgi apparatus);GO:0046872(metal ion binding);GO:0005509(calcium ion binding);GO:0005789(endoplasmic reticulum membrane);GO:0005515(protein binding);GO:0009306(protein secretion);GO:0000137(Golgi cis cisterna);GO:0019538(protein metabolic process);GO:0042984(regulation of amyloid precursor protein biosynthetic process);GO:0005783(endoplasmic reticulum);GO:0005783(endoplasmic reticulum)","NA","NA","NA","N-terminal EF-hand calcium binding protein 3 [Source:HGNC Symbol;Acc:HGNC:15851]",{"v":0.977718806771073,"d":"0.98"},{"v":0.435319987563335,"d":"0.44"},{"v":2.24597729188537,"d":"2.25"},{"v":1.16734334134048,"d":"1.17"},{"v":0.0801967652364055,"d":"0.08"},{"v":0.790413642813808,"d":"0.79"},"up","no"]
["MSTRG.886","NBPF14","MSTRG.886.3;ENST00000619423;ENST00000593495;ENST00000606877;ENST00000621066;ENST00000614329;ENST00000620240;ENST00000611826;ENST00000614999;ENST00000581201","GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0005509(calcium ion binding);GO:0005509(calcium ion binding)","NA","NA","NA","NBPF member 14 [Source:HGNC Symbol;Acc:HGNC:25232]",{"v":5.75763069659954,"d":"5.76"},{"v":2.62387264996699,"d":"2.62"},{"v":2.19432551220501,"d":"2.19"},{"v":1.13377755491623,"d":"1.13"},{"v":0.0802541873165166,"d":"0.08"},{"v":0.790413642813808,"d":"0.79"},"up","no"]
["MSTRG.10091","MCM3AP-AS1","ENST00000432735;ENST00000420074;ENST00000414659;ENST00000590829;ENST00000591223;ENST00000588753;ENST00000444998","NA","NA","NA","NA","MCM3AP antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:16417]",{"v":0.54471356765286,"d":"0.54"},{"v":0.245711539250493,"d":"0.25"},{"v":2.21688232190653,"d":"2.22"},{"v":1.14853219009344,"d":"1.15"},{"v":0.0802734128544681,"d":"0.08"},{"v":0.790413642813808,"d":"0.79"},"up","no"]
["MSTRG.14123","GIMAP8","ENST00000307271","GO:0005737(cytoplasm);GO:0005525(GTP binding);GO:0000166(nucleotide binding);GO:0005794(Golgi apparatus);GO:0005829(cytosol);GO:0005783(endoplasmic reticulum);GO:0005739(mitochondrion)","NA","NA","NA","GTPase, IMAP family member 8 [Source:HGNC Symbol;Acc:HGNC:21792]",{"v":15.261763,"d":"15.26"},{"v":6.957841,"d":"6.96"},{"v":2.19346245480459,"d":"2.19"},{"v":1.13321001215573,"d":"1.13"},{"v":0.0802753600034287,"d":"0.08"},{"v":0.790413642813808,"d":"0.79"},"up","no"]
["MSTRG.4120","TMCO3","ENST00000434316;ENST00000465556;ENST00000473287;ENST00000619336;ENST00000462877;ENST00000375391;ENST00000622371;ENST00000620021;ENST00000491166;ENST00000474393","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0055085(transmembrane transport);GO:0098655(cation transmembrane transport);GO:0006811(ion transport);GO:0015297(antiporter activity);GO:0015299(solute:proton antiporter activity);GO:0006812(cation transport);GO:1902600(hydrogen ion transmembrane transport);GO:0022890(inorganic cation transmembrane transporter activity);GO:0022890(inorganic cation transmembrane transporter activity)","NA","NA","NA","transmembrane and coiled-coil domains 3 [Source:HGNC Symbol;Acc:HGNC:20329]",{"v":1.03447467425771,"d":"1.03"},{"v":2.3672044445085,"d":"2.37"},{"v":0.43700267488831,"d":"0.44"},{"v":-1.19428598441483,"d":"-1.19"},{"v":0.0804161433171345,"d":"0.08"},{"v":0.791152939399456,"d":"0.79"},"down","no"]
["ENSG00000147044","CASK","ENST00000421587;ENST00000378168;ENST00000468986;ENST00000378179;ENST00000477823;ENST00000378158;ENST00000486402;ENST00000378154;ENST00000378163","GO:0005737(cytoplasm);GO:0001953(negative regulation of cell-matrix adhesion);GO:0005634(nucleus);GO:0016020(membrane);GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0005925(focal adhesion);GO:0005516(calmodulin binding);GO:0005829(cytosol);GO:0046037(GMP metabolic process);GO:0046710(GDP metabolic process);GO:0007155(cell adhesion);GO:0015629(actin cytoskeleton);GO:0005730(nucleolus);GO:0007269(neurotransmitter secretion);GO:0005604(basement membrane);GO:0004385(guanylate kinase activity);GO:0010839(negative regulation of keratinocyte proliferation);GO:0061045(negative regulation of wound healing);GO:0090288(negative regulation of cellular response to growth factor stimulus);GO:0005652(nuclear lamina);GO:0005911(cell-cell junction);GO:0016363(nuclear matrix);GO:0042734(presynaptic membrane);GO:0060170(ciliary membrane);GO:0042043(neurexin family protein binding);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0070509(calcium ion import);GO:0090280(positive regulation of calcium ion import);GO:0016323(basolateral plasma membrane);GO:0031982(vesicle);GO:0045202(synapse);GO:0045202(synapse)","NA","NA","NA","calcium/calmodulin dependent serine protein kinase [Source:HGNC Symbol;Acc:HGNC:1497]",{"v":0.757606880805395,"d":"0.76"},{"v":0.33997527780416,"d":"0.34"},{"v":2.22841756523781,"d":"2.23"},{"v":1.15601959302492,"d":"1.16"},{"v":0.0807067789825012,"d":"0.08"},{"v":0.792831979732016,"d":"0.79"},"up","no"]
["MSTRG.3084","LPCAT3","ENST00000261407;ENST00000535479;ENST00000536971;ENST00000620843;ENST00000538987;ENST00000540090;ENST00000545459;ENST00000536797;ENST00000538910;ENST00000540060;ENST00000535021;ENST00000537179","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016740(transferase activity);GO:0016746(transferase activity, transferring acyl groups);GO:0006629(lipid metabolic process);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0008654(phospholipid biosynthetic process);GO:0003841(1-acylglycerol-3-phosphate O-acyltransferase activity);GO:0006644(phospholipid metabolic process);GO:0036150(phosphatidylserine acyl-chain remodeling);GO:0036151(phosphatidylcholine acyl-chain remodeling);GO:0036152(phosphatidylethanolamine acyl-chain remodeling);GO:0047144(2-acylglycerol-3-phosphate O-acyltransferase activity);GO:0047184(1-acylglycerophosphocholine O-acyltransferase activity);GO:0097006(regulation of plasma lipoprotein particle levels);GO:0097006(regulation of plasma lipoprotein particle levels)","00564(Glycerophospholipid metabolism);04216(Ferroptosis);04216(Ferroptosis)","K13515","EC:2.3.1.23;EC:2.3.1.-","lysophosphatidylcholine acyltransferase 3 [Source:HGNC Symbol;Acc:HGNC:30244]",{"v":2.6088431437037,"d":"2.61"},{"v":5.95128524783069,"d":"5.95"},{"v":0.438366341901466,"d":"0.44"},{"v":-1.18979106355053,"d":"-1.19"},{"v":0.0807184858953206,"d":"0.08"},{"v":0.792831979732016,"d":"0.79"},"down","no"]
["ENSG00000122126","OCRL","ENST00000371113;ENST00000463271;ENST00000357121","GO:0016020(membrane);GO:0016787(hydrolase activity);GO:0007165(signal transduction);GO:0005794(Golgi apparatus);GO:0006629(lipid metabolic process);GO:0043547(positive regulation of GTPase activity);GO:0042995(cell projection);GO:0005515(protein binding);GO:0031410(cytoplasmic vesicle);GO:0036092(phosphatidylinositol-3-phosphate biosynthetic process);GO:0005905(clathrin-coated pit);GO:0046856(phosphatidylinositol dephosphorylation);GO:0005768(endosome);GO:0060271(cilium assembly);GO:0005929(cilium);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0005096(GTPase activator activity);GO:0051056(regulation of small GTPase mediated signal transduction);GO:0030670(phagocytic vesicle membrane);GO:0030030(cell projection organization);GO:0061024(membrane organization);GO:0001750(photoreceptor outer segment);GO:0005769(early endosome);GO:0031901(early endosome membrane);GO:0030136(clathrin-coated vesicle);GO:0006661(phosphatidylinositol biosynthetic process);GO:0043647(inositol phosphate metabolic process);GO:0004439(phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity);GO:0034596(phosphatidylinositol phosphate 4-phosphatase activity);GO:0043813(phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity);GO:0052659(inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity);GO:0052658(inositol-1,4,5-trisphosphate 5-phosphatase activity);GO:0005634(nucleus);GO:0005798(Golgi-associated vesicle);GO:0005737(cytoplasm);GO:0005802(trans-Golgi network);GO:0048365(Rac GTPase binding);GO:0052745(inositol phosphate phosphatase activity);GO:0001701(in utero embryonic development);GO:0043087(regulation of GTPase activity);GO:0005795(Golgi stack);GO:0005886(plasma membrane);GO:0005886(plasma membrane)","00562(Inositol phosphate metabolism);04070(Phosphatidylinositol signaling system);04070(Phosphatidylinositol signaling system)","K01099","EC:3.1.3.36","OCRL, inositol polyphosphate-5-phosphatase [Source:HGNC Symbol;Acc:HGNC:8108]",{"v":0.238102875584011,"d":"0.24"},{"v":0.559741925246583,"d":"0.56"},{"v":0.425379741707073,"d":"0.43"},{"v":-1.23317676688891,"d":"-1.23"},{"v":0.0808789766164853,"d":"0.08"},{"v":0.793141081003303,"d":"0.79"},"down","no"]
["ENSG00000232442","MHENCR","ENST00000449500;ENST00000411579","NA","NA","NA","NA","melanoma highly expressed competing endogenous lncRNA for miR-425 and miR-489 [Source:HGNC Symbol;Acc:HGNC:53110]",{"v":2.80048016479401,"d":"2.80"},{"v":1.2269523258427,"d":"1.23"},{"v":2.28246860599948,"d":"2.28"},{"v":1.19059501693224,"d":"1.19"},{"v":0.08091749540882,"d":"0.08"},{"v":0.793141081003303,"d":"0.79"},"up","no"]
["ENSG00000114302","PRKAR2A","ENST00000265563;ENST00000296446;ENST00000457914;ENST00000454963;ENST00000419216","GO:2000480(negative regulation of cAMP-dependent protein kinase activity);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0000166(nucleotide binding);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0045859(regulation of protein kinase activity);GO:0008603(cAMP-dependent protein kinase regulator activity);GO:0030552(cAMP binding);GO:0001932(regulation of protein phosphorylation);GO:0005952(cAMP-dependent protein kinase complex);GO:0005925(focal adhesion);GO:0005813(centrosome);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0031625(ubiquitin protein ligase binding);GO:0035556(intracellular signal transduction);GO:0007596(blood coagulation);GO:0034236(protein kinase A catalytic subunit binding);GO:0003091(renal water homeostasis);GO:0034199(activation of protein kinase A activity);GO:0071377(cellular response to glucagon stimulus);GO:0044853(plasma membrane raft);GO:0097546(ciliary base);GO:0004862(cAMP-dependent protein kinase inhibitor activity);GO:0031588(nucleotide-activated protein kinase complex);GO:0007339(binding of sperm to zona pellucida);GO:0007339(binding of sperm to zona pellucida)","04910(Insulin signaling pathway);04910(Insulin signaling pathway)","K04739","NA","protein kinase cAMP-dependent type II regulatory subunit alpha [Source:HGNC Symbol;Acc:HGNC:9391]",{"v":3.1059405820289,"d":"3.11"},{"v":1.41228492293799,"d":"1.41"},{"v":2.19923085744453,"d":"2.20"},{"v":1.13699905458349,"d":"1.14"},{"v":0.0809475492902391,"d":"0.08"},{"v":0.793141081003303,"d":"0.79"},"up","no"]
["MSTRG.14993","SWI5","ENST00000418976;ENST00000495313;ENST00000419867;ENST00000608796;ENST00000320188","GO:0005634(nucleus);GO:0006281(DNA repair);GO:0006974(cellular response to DNA damage stimulus);GO:0005515(protein binding);GO:0000724(double-strand break repair via homologous recombination);GO:0071479(cellular response to ionizing radiation);GO:0000730(DNA recombinase assembly);GO:0032798(Swi5-Sfr1 complex);GO:0032798(Swi5-Sfr1 complex)","NA","NA","NA","SWI5 homologous recombination repair protein [Source:HGNC Symbol;Acc:HGNC:31412]",{"v":0.617574437234688,"d":"0.62"},{"v":1.46423095573075,"d":"1.46"},{"v":0.421773924951939,"d":"0.42"},{"v":-1.24545818777219,"d":"-1.25"},{"v":0.0811729841187812,"d":"0.08"},{"v":0.794703271291038,"d":"0.79"},"down","no"]
["MSTRG.8752","AC012368.1","ENST00000451350;MSTRG.8752.5;ENST00000436950;ENST00000426365;ENST00000449678;ENST00000413030;ENST00000438115","NA","NA","NA","NA",null,{"v":5.14210816318927,"d":"5.14"},{"v":11.6943011005961,"d":"11.69"},{"v":0.439710600826514,"d":"0.44"},{"v":-1.18537378049581,"d":"-1.19"},{"v":0.0812389741703428,"d":"0.08"},{"v":0.794703271291038,"d":"0.79"},"down","no"]
["ENSG00000075651","PLD1","ENST00000356327;ENST00000351298;ENST00000467432;ENST00000471075;ENST00000481505;ENST00000331659;ENST00000465816;ENST00000497307;ENST00000498278;ENST00000446289","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0016787(hydrolase activity);GO:0003824(catalytic activity);GO:0005794(Golgi apparatus);GO:0005765(lysosomal membrane);GO:0006629(lipid metabolic process);GO:0016042(lipid catabolic process);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005515(protein binding);GO:0000139(Golgi membrane);GO:0048471(perinuclear region of cytoplasm);GO:0035091(phosphatidylinositol binding);GO:0005886(plasma membrane);GO:0005768(endosome);GO:0031902(late endosome membrane);GO:0043312(neutrophil degranulation);GO:0035579(specific granule membrane);GO:0070821(tertiary granule membrane);GO:0016324(apical plasma membrane);GO:0006935(chemotaxis);GO:0007264(small GTPase mediated signal transduction);GO:0032534(regulation of microvillus assembly);GO:0007265(Ras protein signal transduction);GO:0004630(phospholipase D activity);GO:0070290(N-acylphosphatidylethanolamine-specific phospholipase D activity);GO:0006654(phosphatidic acid biosynthetic process);GO:0048870(cell motility);GO:0030139(endocytic vesicle);GO:0030139(endocytic vesicle)","00564(Glycerophospholipid metabolism);00565(Ether lipid metabolism);04014(Ras signaling pathway);04072(Phospholipase D signaling pathway);04071(Sphingolipid signaling pathway);04024(cAMP signaling pathway);04144(Endocytosis);04666(Fc gamma R-mediated phagocytosis);04912(GnRH signaling pathway);04724(Glutamatergic synapse);05200(Pathways in cancer);05231(Choline metabolism in cancer);05212(Pancreatic cancer);05212(Pancreatic cancer)","K01115","EC:3.1.4.4","phospholipase D1 [Source:HGNC Symbol;Acc:HGNC:9067]",{"v":0.203294806283537,"d":"0.20"},{"v":0.468929184462244,"d":"0.47"},{"v":0.433529865531125,"d":"0.43"},{"v":-1.20579671189122,"d":"-1.21"},{"v":0.0813586682057723,"d":"0.08"},{"v":0.795054904916709,"d":"0.80"},"down","no"]
["MSTRG.14581","TMEM71;LRRC6","ENST00000377901;MSTRG.14581.11;ENST00000522334;ENST00000519304;ENST00000517538;ENST00000522597;ENST00000519085;ENST00000524079;ENST00000522780;ENST00000520446;ENST00000356838;ENST00000518101;ENST00000250173;ENST00000519016;ENST00000620350;ENST00000518642;ENST00000523829;ENST00000618342;ENST00000522594;ENST00000519595;ENST00000521430","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005739(mitochondrion);GO:0005737(cytoplasm);GO:0042995(cell projection);GO:0005515(protein binding);GO:0005929(cilium);GO:0003674(molecular_function);GO:0008584(male gonad development);GO:0003341(cilium movement);GO:0060287(epithelial cilium movement involved in determination of left/right asymmetry);GO:0030317(flagellated sperm motility);GO:0036158(outer dynein arm assembly);GO:0036159(inner dynein arm assembly);GO:0044458(motile cilium assembly);GO:0061458(reproductive system development);GO:0061458(reproductive system development)","NA","NA","NA","transmembrane protein 71 [Source:HGNC Symbol;Acc:HGNC:26572];leucine rich repeat containing 6 [Source:HGNC Symbol;Acc:HGNC:16725]",{"v":2.04507264749734,"d":"2.05"},{"v":4.63751329259851,"d":"4.64"},{"v":0.440984751625679,"d":"0.44"},{"v":-1.18119932376295,"d":"-1.18"},{"v":0.0814069670953581,"d":"0.08"},{"v":0.795054904916709,"d":"0.80"},"down","no"]
["MSTRG.2735","PAK1","ENST00000356341;MSTRG.2735.1;ENST00000278568;ENST00000530617;ENST00000527457;ENST00000526910;ENST00000532991;ENST00000530358;ENST00000528633;ENST00000526103;ENST00000528203;ENST00000533568;ENST00000528592;ENST00000533468;ENST00000532711;ENST00000529248","GO:0008284(positive regulation of cell proliferation);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0005829(cytosol);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0005886(plasma membrane);GO:0042995(cell projection);GO:0005515(protein binding);GO:0003824(catalytic activity);GO:0008152(metabolic process);GO:0006915(apoptotic process);GO:0030054(cell junction);GO:0005925(focal adhesion);GO:0030425(dendrite);GO:0038095(Fc-epsilon receptor signaling pathway);GO:0038096(Fc-gamma receptor signaling pathway involved in phagocytosis);GO:0006887(exocytosis);GO:0030424(axon);GO:0048812(neuron projection morphogenesis);GO:0001934(positive regulation of protein phosphorylation);GO:0033138(positive regulation of peptidyl-serine phosphorylation);GO:0031941(filamentous actin);GO:0002223(stimulatory C-type lectin receptor signaling pathway);GO:0050852(T cell receptor signaling pathway);GO:0032587(ruffle membrane);GO:0030335(positive regulation of cell migration);GO:0043234(protein complex);GO:0071437(invadopodium);GO:0007266(Rho protein signal transduction);GO:0001726(ruffle);GO:0031965(nuclear membrane);GO:0014704(intercalated disc);GO:0042981(regulation of apoptotic process);GO:0048013(ephrin receptor signaling pathway);GO:0046777(protein autophosphorylation);GO:0005911(cell-cell junction);GO:0007346(regulation of mitotic cell cycle);GO:0030018(Z disc);GO:0033148(positive regulation of intracellular estrogen receptor signaling pathway);GO:0051496(positive regulation of stress fiber assembly);GO:0042060(wound healing);GO:0031532(actin cytoskeleton reorganization);GO:0048754(branching morphogenesis of an epithelial tube);GO:0031295(T cell costimulation);GO:0048365(Rac GTPase binding);GO:0043507(positive regulation of JUN kinase activity);GO:0005518(collagen binding);GO:0050770(regulation of axonogenesis);GO:0032147(activation of protein kinase activity);GO:0031116(positive regulation of microtubule polymerization);GO:0048012(hepatocyte growth factor receptor signaling pathway);GO:0060244(negative regulation of cell proliferation involved in contact inhibition);GO:0019901(protein kinase binding);GO:0001666(response to hypoxia);GO:0010033(response to organic substance);GO:0010763(positive regulation of fibroblast migration);GO:0021549(cerebellum development);GO:0030010(establishment of cell polarity);GO:0032869(cellular response to insulin stimulus);GO:0032956(regulation of actin cytoskeleton organization);GO:0045773(positive regulation of axon extension);GO:0061052(negative regulation of cell growth involved in cardiac muscle cell development);GO:0090314(positive regulation of protein targeting to membrane);GO:1904707(positive regulation of vascular smooth muscle cell proliferation);GO:1904754(positive regulation of vascular associated smooth muscle cell migration);GO:2001275(positive regulation of glucose import in response to insulin stimulus);GO:0030027(lamellipodium);GO:0030027(lamellipodium)","04014(Ras signaling pathway);04010(MAPK signaling pathway);04012(ErbB signaling pathway);04392(Hippo signaling pathway - multiple species);04024(cAMP signaling pathway);04510(Focal adhesion);04810(Regulation of actin cytoskeleton);04650(Natural killer cell mediated cytotoxicity);04660(T cell receptor signaling pathway);04666(Fc gamma R-mediated phagocytosis);04062(Chemokine signaling pathway);04360(Axon guidance);05205(Proteoglycans in cancer);05211(Renal cell carcinoma);05120(Epithelial cell signaling in Helicobacter pylori infection);05120(Epithelial cell signaling in Helicobacter pylori infection)","K04409","EC:2.7.11.1","p21 (RAC1) activated kinase 1 [Source:HGNC Symbol;Acc:HGNC:8590]",{"v":9.74953933744466,"d":"9.75"},{"v":22.0913332610689,"d":"22.09"},{"v":0.441328697649321,"d":"0.44"},{"v":-1.18007453245849,"d":"-1.18"},{"v":0.0816815615659851,"d":"0.08"},{"v":0.796745470001117,"d":"0.80"},"down","no"]
["ENSG00000086848","ALG9","ENST00000532425;ENST00000398006;ENST00000524671;ENST00000527714;ENST00000616540;ENST00000614444;ENST00000527212;ENST00000612489;ENST00000531154;ENST00000530723","GO:0016757(transferase activity, transferring glycosyl groups);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016740(transferase activity);GO:0006486(protein glycosylation);GO:0000030(mannosyltransferase activity);GO:0097502(mannosylation);GO:0006488(dolichol-linked oligosaccharide biosynthetic process);GO:0000026(alpha-1,2-mannosyltransferase activity);GO:0052918(dol-P-Man:Man(8)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase activity);GO:0052926(dol-P-Man:Man(6)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase activity);GO:0052926(dol-P-Man:Man(6)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase activity)","00510(N-Glycan biosynthesis);00510(N-Glycan biosynthesis)","K03846","EC:2.4.1.259;EC:2.4.1.261","ALG9, alpha-1,2-mannosyltransferase [Source:HGNC Symbol;Acc:HGNC:15672]",{"v":0.463055945588419,"d":"0.46"},{"v":0.208696811681018,"d":"0.21"},{"v":2.21879741170256,"d":"2.22"},{"v":1.14977794762743,"d":"1.15"},{"v":0.0817931530768677,"d":"0.08"},{"v":0.796745470001117,"d":"0.80"},"up","no"]
["ENSG00000103522","IL21R","ENST00000337929;ENST00000564089;ENST00000564583;ENST00000561953;ENST00000395754","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0004896(cytokine receptor activity);GO:0019221(cytokine-mediated signaling pathway);GO:0030101(natural killer cell activation);GO:0001532(interleukin-21 receptor activity);GO:0038114(interleukin-21-mediated signaling pathway);GO:0038114(interleukin-21-mediated signaling pathway)","04630(Jak-STAT signaling pathway);04060(Cytokine-cytokine receptor interaction);04659(Th17 cell differentiation);05321(Inflammatiory bowel disease (IBD));05321(Inflammatiory bowel disease (IBD))","K05075","NA","interleukin 21 receptor [Source:HGNC Symbol;Acc:HGNC:6006]",{"v":3.88045232778489,"d":"3.88"},{"v":1.76811661514542,"d":"1.77"},{"v":2.19468121873044,"d":"2.19"},{"v":1.13401140101073,"d":"1.13"},{"v":0.0818767238926595,"d":"0.08"},{"v":0.796745470001117,"d":"0.80"},"up","no"]
["ENSG00000161381","PLXDC1","ENST00000578390;ENST00000315392;ENST00000578808;ENST00000579417;ENST00000394318;ENST00000578277;ENST00000580667;ENST00000579190;ENST00000582025;ENST00000444911;ENST00000441877;ENST00000578517","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005886(plasma membrane);GO:0005576(extracellular region);GO:0030054(cell junction);GO:0001525(angiogenesis);GO:0005923(bicellular tight junction);GO:0005515(protein binding);GO:0043235(receptor complex);GO:0021510(spinal cord development);GO:0030425(dendrite);GO:0043025(neuronal cell body);GO:0043025(neuronal cell body)","NA","NA","NA","plexin domain containing 1 [Source:HGNC Symbol;Acc:HGNC:20945]",{"v":0.763137665948044,"d":"0.76"},{"v":0.344966864395818,"d":"0.34"},{"v":2.21220570643682,"d":"2.21"},{"v":1.14548554373622,"d":"1.15"},{"v":0.0818996659644301,"d":"0.08"},{"v":0.796745470001117,"d":"0.80"},"up","no"]
["MSTRG.14353","RB1CC1","ENST00000435644;ENST00000025008;ENST00000519912;ENST00000518710;ENST00000523594;ENST00000522957;ENST00000518211","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0031965(nuclear membrane);GO:0005515(protein binding);GO:0007049(cell cycle);GO:0006914(autophagy);GO:0034045(pre-autophagosomal structure membrane);GO:0005789(endoplasmic reticulum membrane);GO:0000045(autophagosome assembly);GO:0000422(mitophagy);GO:0019901(protein kinase binding);GO:0016241(regulation of macroautophagy);GO:0016236(macroautophagy);GO:0000407(pre-autophagosomal structure);GO:1990316(ATG1/ULK1 kinase complex);GO:0061723(glycophagy);GO:0030242(pexophagy);GO:0032947(protein complex scaffold);GO:0001889(liver development);GO:0001934(positive regulation of protein phosphorylation);GO:0007507(heart development);GO:0043066(negative regulation of apoptotic process);GO:0045793(positive regulation of cell size);GO:0046330(positive regulation of JNK cascade);GO:0061709(reticulophagy);GO:2001237(negative regulation of extrinsic apoptotic signaling pathway);GO:2001237(negative regulation of extrinsic apoptotic signaling pathway)","04140(Autophagy - animal);04211(Longevity regulating pathway - mammal);04211(Longevity regulating pathway - mammal)","K17589","NA","RB1 inducible coiled-coil 1 [Source:HGNC Symbol;Acc:HGNC:15574]",{"v":2.77202994051215,"d":"2.77"},{"v":6.28493754957321,"d":"6.28"},{"v":0.44105926568839,"d":"0.44"},{"v":-1.18095556933143,"d":"-1.18"},{"v":0.0819108862200118,"d":"0.08"},{"v":0.796745470001117,"d":"0.80"},"down","no"]
["ENSG00000188868","ZNF563","ENST00000293725;ENST00000595977;ENST00000594577","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0005622(intracellular);GO:0005622(intracellular)","NA","NA","NA","zinc finger protein 563 [Source:HGNC Symbol;Acc:HGNC:30498]",{"v":0.600977321742185,"d":"0.60"},{"v":0.261211144362487,"d":"0.26"},{"v":2.30073384965612,"d":"2.30"},{"v":1.20209410134142,"d":"1.20"},{"v":0.0819968052434574,"d":"0.08"},{"v":0.796937472753603,"d":"0.80"},"up","no"]
["MSTRG.2218","DENND5A","ENST00000529977;ENST00000328194;ENST00000527700;ENST00000525784;ENST00000526707;ENST00000531747;ENST00000530044;ENST00000531580;ENST00000530867;ENST00000533737;ENST00000526523;ENST00000532696;ENST00000527896;ENST00000530780;ENST00000528725","GO:0016020(membrane);GO:0005794(Golgi apparatus);GO:0043547(positive regulation of GTPase activity);GO:0000139(Golgi membrane);GO:0070588(calcium ion transmembrane transport);GO:0005085(guanyl-nucleotide exchange factor activity);GO:0005829(cytosol);GO:0017112(Rab guanyl-nucleotide exchange factor activity);GO:0061024(membrane organization);GO:0005802(trans-Golgi network);GO:0042147(retrograde transport, endosome to Golgi);GO:0010977(negative regulation of neuron projection development);GO:0030904(retromer complex);GO:0005262(calcium channel activity);GO:0050982(detection of mechanical stimulus);GO:0017137(Rab GTPase binding);GO:0017137(Rab GTPase binding)","NA","NA","NA","DENN domain containing 5A [Source:HGNC Symbol;Acc:HGNC:19344]",{"v":7.52189827532377,"d":"7.52"},{"v":17.0105618699121,"d":"17.01"},{"v":0.442189877844561,"d":"0.44"},{"v":-1.17726209404484,"d":"-1.18"},{"v":0.0822779398760815,"d":"0.08"},{"v":0.797855256701483,"d":"0.80"},"down","no"]
["ENSG00000139324","TMTC3","ENST00000266712;ENST00000547034","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005783(endoplasmic reticulum);GO:0005515(protein binding);GO:0034976(response to endoplasmic reticulum stress);GO:1901800(positive regulation of proteasomal protein catabolic process);GO:1901800(positive regulation of proteasomal protein catabolic process)","NA","NA","NA","transmembrane and tetratricopeptide repeat containing 3 [Source:HGNC Symbol;Acc:HGNC:26899]",{"v":0.239388466357309,"d":"0.24"},{"v":0.559411700013648,"d":"0.56"},{"v":0.427928958853504,"d":"0.43"},{"v":-1.22455678241187,"d":"-1.22"},{"v":0.0822786321917805,"d":"0.08"},{"v":0.797855256701483,"d":"0.80"},"down","no"]
["MSTRG.3346","AC011603.2","MSTRG.3346.1;ENST00000547712;ENST00000547387;ENST00000548149;ENST00000552893;ENST00000551496","NA","NA","NA","NA",null,{"v":4.63205169399214,"d":"4.63"},{"v":2.09930090623245,"d":"2.10"},{"v":2.20647344086805,"d":"2.21"},{"v":1.14174238182169,"d":"1.14"},{"v":0.0822900040544131,"d":"0.08"},{"v":0.797855256701483,"d":"0.80"},"up","no"]
["ENSG00000151746","BICD1","ENST00000548411;ENST00000552226;ENST00000281474;ENST00000614004;ENST00000552160;ENST00000547680;ENST00000551848","GO:0048471(perinuclear region of cytoplasm);GO:0006810(transport);GO:0005794(Golgi apparatus);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0005829(cytosol);GO:0016032(viral process);GO:0005200(structural constituent of cytoskeleton);GO:0031410(cytoplasmic vesicle);GO:0009653(anatomical structure morphogenesis);GO:0048260(positive regulation of receptor-mediated endocytosis);GO:0006396(RNA processing);GO:0016020(membrane);GO:0008093(cytoskeletal adaptor activity);GO:0017137(Rab GTPase binding);GO:0005881(cytoplasmic microtubule);GO:0005802(trans-Golgi network);GO:0070840(dynein complex binding);GO:0072385(minus-end-directed organelle transport along microtubule);GO:0034452(dynactin binding);GO:0033365(protein localization to organelle);GO:0034063(stress granule assembly);GO:0072393(microtubule anchoring at microtubule organizing center);GO:0045298(tubulin complex);GO:0031871(proteinase activated receptor binding);GO:0008298(intracellular mRNA localization);GO:1900275(negative regulation of phospholipase C activity);GO:1900276(regulation of proteinase activated receptor activity);GO:1900737(negative regulation of phospholipase C-activating G-protein coupled receptor signaling pathway);GO:0072517(host cell viral assembly compartment);GO:0072517(host cell viral assembly compartment)","NA","NA","NA","BICD cargo adaptor 1 [Source:HGNC Symbol;Acc:HGNC:1049]",{"v":0.560182314034815,"d":"0.56"},{"v":0.253195265309294,"d":"0.25"},{"v":2.21245177452476,"d":"2.21"},{"v":1.14564600868163,"d":"1.15"},{"v":0.0825798897834931,"d":"0.08"},{"v":0.800021748007099,"d":"0.80"},"up","no"]
["MSTRG.104","VAMP3","ENST00000054666;ENST00000470357;ENST00000487194","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0015031(protein transport);GO:0016192(vesicle-mediated transport);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0030054(cell junction);GO:0045202(synapse);GO:0006906(vesicle fusion);GO:0043231(intracellular membrane-bounded organelle);GO:0005622(intracellular);GO:0061024(membrane organization);GO:0002479(antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent);GO:0042147(retrograde transport, endosome to Golgi);GO:0000149(SNARE binding);GO:0005484(SNAP receptor activity);GO:0061025(membrane fusion);GO:0030670(phagocytic vesicle membrane);GO:0031201(SNARE complex);GO:0043005(neuron projection);GO:0032588(trans-Golgi network membrane);GO:0030136(clathrin-coated vesicle);GO:0006461(protein complex assembly);GO:0030133(transport vesicle);GO:0006887(exocytosis);GO:0030665(clathrin-coated vesicle membrane);GO:0001921(positive regulation of receptor recycling);GO:0055038(recycling endosome membrane);GO:0034446(substrate adhesion-dependent cell spreading);GO:0055037(recycling endosome);GO:0017075(syntaxin-1 binding);GO:0006904(vesicle docking involved in exocytosis);GO:0017156(calcium ion regulated exocytosis);GO:0035493(SNARE complex assembly);GO:0043001(Golgi to plasma membrane protein transport);GO:1903531(negative regulation of secretion by cell);GO:0009986(cell surface);GO:0016324(apical plasma membrane);GO:0030141(secretory granule);GO:0031410(cytoplasmic vesicle);GO:0043229(intracellular organelle);GO:0048471(perinuclear region of cytoplasm);GO:0048471(perinuclear region of cytoplasm)","04130(SNARE interactions in vesicular transport);04145(Phagosome);04145(Phagosome)","K13505","NA","vesicle associated membrane protein 3 [Source:HGNC Symbol;Acc:HGNC:12644]",{"v":7.01447348478261,"d":"7.01"},{"v":15.8614193351449,"d":"15.86"},{"v":0.442234918361959,"d":"0.44"},{"v":-1.17711515168993,"d":"-1.18"},{"v":0.0828217010490969,"d":"0.08"},{"v":0.800688381835651,"d":"0.80"},"down","no"]
["MSTRG.6759","PSMB3","ENST00000619426;ENST00000614132;ENST00000613870;ENST00000620309;ENST00000618159","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016787(hydrolase activity);GO:0005515(protein binding);GO:0008233(peptidase activity);GO:0006508(proteolysis);GO:0000502(proteasome complex);GO:0043161(proteasome-mediated ubiquitin-dependent protein catabolic process);GO:0004175(endopeptidase activity);GO:0004298(threonine-type endopeptidase activity);GO:0051603(proteolysis involved in cellular protein catabolic process);GO:0005839(proteasome core complex);GO:0038095(Fc-epsilon receptor signaling pathway);GO:0019774(proteasome core complex, beta-subunit complex);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0000165(MAPK cascade);GO:0000209(protein polyubiquitination);GO:0002223(stimulatory C-type lectin receptor signaling pathway);GO:0002479(antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent);GO:0006521(regulation of cellular amino acid metabolic process);GO:0010972(negative regulation of G2/M transition of mitotic cell cycle);GO:0016579(protein deubiquitination);GO:0031145(anaphase-promoting complex-dependent catabolic process);GO:0031146(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process);GO:0033209(tumor necrosis factor-mediated signaling pathway);GO:0038061(NIK/NF-kappaB signaling);GO:0043488(regulation of mRNA stability);GO:0043687(post-translational protein modification);GO:0050852(T cell receptor signaling pathway);GO:0051437(positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition);GO:0055085(transmembrane transport);GO:0060071(Wnt signaling pathway, planar cell polarity pathway);GO:0061418(regulation of transcription from RNA polymerase II promoter in response to hypoxia);GO:0090090(negative regulation of canonical Wnt signaling pathway);GO:0090263(positive regulation of canonical Wnt signaling pathway);GO:1902036(regulation of hematopoietic stem cell differentiation);GO:0016032(viral process);GO:0051436(negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle);GO:0051436(negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle)","03050(Proteasome);03050(Proteasome)","K02735","EC:3.4.25.1","proteasome subunit beta 3 [Source:HGNC Symbol;Acc:HGNC:9540]",{"v":15.2615765945717,"d":"15.26"},{"v":34.5506202892282,"d":"34.55"},{"v":0.441716428440788,"d":"0.44"},{"v":-1.17880760439452,"d":"-1.18"},{"v":0.082887148717593,"d":"0.08"},{"v":0.800688381835651,"d":"0.80"},"down","no"]
["ENSG00000157693","TMEM268","ENST00000374049;ENST00000288502;ENST00000471206","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0003674(molecular_function);GO:0008150(biological_process);GO:0005575(cellular_component);GO:0005575(cellular_component)","NA","NA","NA","transmembrane protein 268 [Source:HGNC Symbol;Acc:HGNC:24513]",{"v":1.08338119365609,"d":"1.08"},{"v":2.46645383764608,"d":"2.47"},{"v":0.439246491104022,"d":"0.44"},{"v":-1.18689733349616,"d":"-1.19"},{"v":0.0828897256132187,"d":"0.08"},{"v":0.800688381835651,"d":"0.80"},"down","no"]
["MSTRG.15451","FAM45BP","ENST00000592932;ENST00000408950","NA","NA","NA","NA","family with sequence similarity 45 member B, pseudogene [Source:HGNC Symbol;Acc:HGNC:30886]",{"v":1.38172885591133,"d":"1.38"},{"v":3.183407,"d":"3.18"},{"v":0.434040905203554,"d":"0.43"},{"v":-1.20409708227886,"d":"-1.20"},{"v":0.0829458053234154,"d":"0.08"},{"v":0.800688381835651,"d":"0.80"},"down","no"]
["MSTRG.1922","TWNK","ENST00000476766;ENST00000370228;ENST00000459764;ENST00000473656;ENST00000311916","GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0016787(hydrolase activity);GO:0004386(helicase activity);GO:0005739(mitochondrion);GO:0006260(DNA replication);GO:0003678(DNA helicase activity);GO:0005759(mitochondrial matrix);GO:0034214(protein hexamerization);GO:0006264(mitochondrial DNA replication);GO:0006268(DNA unwinding involved in DNA replication);GO:0071333(cellular response to glucose stimulus);GO:0002020(protease binding);GO:0006390(transcription from mitochondrial promoter);GO:0007005(mitochondrion organization);GO:0042645(mitochondrial nucleoid);GO:0003697(single-stranded DNA binding);GO:0051260(protein homooligomerization);GO:0043139(5'-3' DNA helicase activity);GO:0043139(5'-3' DNA helicase activity)","NA","NA","NA","twinkle mtDNA helicase [Source:HGNC Symbol;Acc:HGNC:1160]",{"v":1.05924282639681,"d":"1.06"},{"v":0.472434464367161,"d":"0.47"},{"v":2.24209473755412,"d":"2.24"},{"v":1.16484723912099,"d":"1.16"},{"v":0.0829811576591008,"d":"0.08"},{"v":0.800688381835651,"d":"0.80"},"up","no"]
["MSTRG.9553","SIRPG","ENST00000344103;ENST00000303415;ENST00000497407;ENST00000478145;ENST00000381580","GO:0005622(intracellular);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0007155(cell adhesion);GO:0005515(protein binding);GO:0050900(leukocyte migration);GO:0005886(plasma membrane);GO:0050870(positive regulation of T cell activation);GO:0008284(positive regulation of cell proliferation);GO:0007267(cell-cell signaling);GO:0008285(negative regulation of cell proliferation);GO:0035556(intracellular signal transduction);GO:0022409(positive regulation of cell-cell adhesion);GO:0022409(positive regulation of cell-cell adhesion)","04380(Osteoclast differentiation);04380(Osteoclast differentiation)","K06551","NA","signal regulatory protein gamma [Source:HGNC Symbol;Acc:HGNC:15757]",{"v":5.81734335236396,"d":"5.82"},{"v":2.6537596440678,"d":"2.65"},{"v":2.19211388091157,"d":"2.19"},{"v":1.13232274864456,"d":"1.13"},{"v":0.0831027133045751,"d":"0.08"},{"v":0.801219274310403,"d":"0.80"},"up","no"]
["MSTRG.677","SELENOF","ENST00000616787;ENST00000331835;ENST00000611507;ENST00000467557;ENST00000370554;ENST00000401030","NA","NA","NA","NA","selenoprotein F [Source:HGNC Symbol;Acc:HGNC:17705]",{"v":9.3770427446505,"d":"9.38"},{"v":21.2058389643367,"d":"21.21"},{"v":0.442191547357335,"d":"0.44"},{"v":-1.17725664707878,"d":"-1.18"},{"v":0.0832329210044264,"d":"0.08"},{"v":0.801269689059429,"d":"0.80"},"down","no"]
["MSTRG.7236","RNF157","ENST00000269391;ENST00000319945;ENST00000592869;ENST00000592271;ENST00000589317;ENST00000593155;ENST00000591615","GO:0046872(metal ion binding);GO:0046872(metal ion binding)","NA","NA","NA","ring finger protein 157 [Source:HGNC Symbol;Acc:HGNC:29402]",{"v":4.22652223352986,"d":"4.23"},{"v":1.93909546821328,"d":"1.94"},{"v":2.17963597090156,"d":"2.18"},{"v":1.12408720526413,"d":"1.12"},{"v":0.0832410215091634,"d":"0.08"},{"v":0.801269689059429,"d":"0.80"},"up","no"]
["ENSG00000187951","ARHGAP11B","ENST00000602616;ENST00000567449;ENST00000566548;ENST00000622744;ENST00000564902;ENST00000566362;ENST00000563110","GO:0007165(signal transduction);GO:0043547(positive regulation of GTPase activity);GO:0005829(cytosol);GO:0005096(GTPase activator activity);GO:0051056(regulation of small GTPase mediated signal transduction);GO:0021987(cerebral cortex development);GO:0021987(cerebral cortex development)","NA","NA","NA","Rho GTPase activating protein 11B [Source:HGNC Symbol;Acc:HGNC:15782]",{"v":0.381494510670732,"d":"0.38"},{"v":0.168508893945993,"d":"0.17"},{"v":2.26394288002983,"d":"2.26"},{"v":1.17883755899256,"d":"1.18"},{"v":0.0833364545574438,"d":"0.08"},{"v":0.801547592476628,"d":"0.80"},"up","no"]
["ENSG00000145685","LHFPL2","ENST00000515007;ENST00000512759;ENST00000503686;ENST00000380345;ENST00000502722","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005886(plasma membrane);GO:0003674(molecular_function);GO:0008150(biological_process);GO:0005575(cellular_component);GO:0002576(platelet degranulation);GO:0031092(platelet alpha granule membrane);GO:0031092(platelet alpha granule membrane)","NA","NA","NA","LHFPL tetraspan subfamily member 2 [Source:HGNC Symbol;Acc:HGNC:6588]",{"v":0.554866157076595,"d":"0.55"},{"v":1.26412659044754,"d":"1.26"},{"v":0.438932430714993,"d":"0.44"},{"v":-1.18792922659642,"d":"-1.19"},{"v":0.08345039653433,"d":"0.08"},{"v":0.802002933013888,"d":"0.80"},"down","no"]
["MSTRG.927","CTSS","ENST00000480760;ENST00000368985;ENST00000483930;ENST00000448301;ENST00000472977;ENST00000607427;MSTRG.927.1","GO:0005615(extracellular space);GO:0043231(intracellular membrane-bounded organelle);GO:0016787(hydrolase activity);GO:0008233(peptidase activity);GO:0008234(cysteine-type peptidase activity);GO:0006508(proteolysis);GO:0005576(extracellular region);GO:0005764(lysosome);GO:0002250(adaptive immune response);GO:0004252(serine-type endopeptidase activity);GO:0043312(neutrophil degranulation);GO:0019886(antigen processing and presentation of exogenous peptide antigen via MHC class II);GO:0006955(immune response);GO:0002224(toll-like receptor signaling pathway);GO:1904813(ficolin-1-rich granule lumen);GO:1904724(tertiary granule lumen);GO:0043202(lysosomal lumen);GO:0022617(extracellular matrix disassembly);GO:0004197(cysteine-type endopeptidase activity);GO:0019882(antigen processing and presentation);GO:0001968(fibronectin binding);GO:0005518(collagen binding);GO:0043394(proteoglycan binding);GO:0030574(collagen catabolic process);GO:0051603(proteolysis involved in cellular protein catabolic process);GO:0097067(cellular response to thyroid hormone stimulus);GO:0036021(endolysosome lumen);GO:0043236(laminin binding);GO:0010447(response to acidic pH);GO:0016485(protein processing);GO:0034769(basement membrane disassembly);GO:0048002(antigen processing and presentation of peptide antigen);GO:2001259(positive regulation of cation channel activity);GO:2001259(positive regulation of cation channel activity)","04145(Phagosome);04142(Lysosome);04210(Apoptosis);04612(Antigen processing and presentation);05152(Tuberculosis);05152(Tuberculosis)","K01368","EC:3.4.22.27","cathepsin S [Source:HGNC Symbol;Acc:HGNC:2545]",{"v":60.5075802768046,"d":"60.51"},{"v":136.242454222907,"d":"136.24"},{"v":0.444116928324029,"d":"0.44"},{"v":-1.17098853159029,"d":"-1.17"},{"v":0.083671803882386,"d":"0.08"},{"v":0.803453016879419,"d":"0.80"},"down","no"]
["ENSG00000173295","FAM86B3P","ENST00000590591;ENST00000310542;ENST00000588728;ENST00000522601","NA","NA","NA","NA","family with sequence similarity 86 member B3, pseudogene [Source:HGNC Symbol;Acc:HGNC:44371]",{"v":0.166463450513347,"d":"0.17"},{"v":0.395916916016427,"d":"0.40"},{"v":0.420450462658282,"d":"0.42"},{"v":-1.24999226227186,"d":"-1.25"},{"v":0.0837801322095195,"d":"0.08"},{"v":0.803453016879419,"d":"0.80"},"down","no"]
["ENSG00000131747","TOP2A","ENST00000423485;ENST00000577706","GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0016853(isomerase activity);GO:0005730(nucleolus);GO:0003677(DNA binding);GO:0006259(DNA metabolic process);GO:0042803(protein homodimerization activity);GO:0005515(protein binding);GO:0003916(DNA topoisomerase activity);GO:0006265(DNA topological change);GO:0006974(cellular response to DNA damage stimulus);GO:0048511(rhythmic process);GO:0000287(magnesium ion binding);GO:0005654(nucleoplasm);GO:0000712(resolution of meiotic recombination intermediates);GO:0007059(chromosome segregation);GO:0005814(centriole);GO:0003682(chromatin binding);GO:0043234(protein complex);GO:0043065(positive regulation of apoptotic process);GO:0008022(protein C-terminus binding);GO:0003918(DNA topoisomerase type II (ATP-hydrolyzing) activity);GO:0043130(ubiquitin binding);GO:0019899(enzyme binding);GO:0046982(protein heterodimerization activity);GO:0008144(drug binding);GO:0042752(regulation of circadian rhythm);GO:0008094(DNA-dependent ATPase activity);GO:0008301(DNA binding, bending);GO:0042826(histone deacetylase binding);GO:0016925(protein sumoylation);GO:0000228(nuclear chromosome);GO:0045070(positive regulation of viral genome replication);GO:0030263(apoptotic chromosome condensation);GO:0005080(protein kinase C binding);GO:0019035(viral integration complex);GO:0000819(sister chromatid segregation);GO:0002244(hematopoietic progenitor cell differentiation);GO:0006266(DNA ligation);GO:0030261(chromosome condensation);GO:0040016(embryonic cleavage);GO:0044774(mitotic DNA integrity checkpoint);GO:0045870(positive regulation of single stranded viral RNA replication via double stranded DNA intermediate);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0000793(condensed chromosome);GO:0009330(DNA topoisomerase complex (ATP-hydrolyzing));GO:0009330(DNA topoisomerase complex (ATP-hydrolyzing))","01524(Platinum drug resistance);01524(Platinum drug resistance)","K03164","EC:5.99.1.3","topoisomerase (DNA) II alpha [Source:HGNC Symbol;Acc:HGNC:11989]",{"v":0.607843255553829,"d":"0.61"},{"v":0.272893598260059,"d":"0.27"},{"v":2.22740020077193,"d":"2.23"},{"v":1.1553607928799,"d":"1.16"},{"v":0.0838014440458853,"d":"0.08"},{"v":0.803453016879419,"d":"0.80"},"up","no"]
["MSTRG.11076","ZNF654","ENST00000636215;ENST00000473136;ENST00000309495;ENST00000623596","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0003677(DNA binding)","NA","NA","NA","zinc finger protein 654 [Source:HGNC Symbol;Acc:HGNC:25612]",{"v":0.697833169171824,"d":"0.70"},{"v":1.58219483053345,"d":"1.58"},{"v":0.441053880157442,"d":"0.44"},{"v":-1.18097318539084,"d":"-1.18"},{"v":0.0840076157769594,"d":"0.08"},{"v":0.80478894923321,"d":"0.80"},"down","no"]
["ENSG00000177150","FAM210A","ENST00000402563;ENST00000592976;ENST00000591269;ENST00000322247;ENST00000588475;ENST00000589346","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005739(mitochondrion);GO:0005739(mitochondrion)","NA","NA","NA","family with sequence similarity 210 member A [Source:HGNC Symbol;Acc:HGNC:28346]",{"v":0.735768827173681,"d":"0.74"},{"v":0.327809800683615,"d":"0.33"},{"v":2.24449917494629,"d":"2.24"},{"v":1.1663935659344,"d":"1.17"},{"v":0.0840821889304645,"d":"0.08"},{"v":0.804863051749327,"d":"0.80"},"up","no"]
["MSTRG.2669","LAMTOR1","ENST00000538404;ENST00000278671;ENST00000544594;ENST00000545249;ENST00000535107;ENST00000541403;ENST00000535872;ENST00000539797","GO:0045121(membrane raft);GO:0032008(positive regulation of TOR signaling);GO:0071230(cellular response to amino acid stimulus);GO:0071986(Ragulator complex);GO:0007040(lysosome organization);GO:0031902(late endosome membrane);GO:0001919(regulation of receptor recycling);GO:0032439(endosome localization);GO:0042632(cholesterol homeostasis);GO:0043410(positive regulation of MAPK cascade);GO:0016020(membrane);GO:0005765(lysosomal membrane);GO:0005886(plasma membrane);GO:0043547(positive regulation of GTPase activity);GO:0005515(protein binding);GO:0005764(lysosome);GO:0005085(guanyl-nucleotide exchange factor activity);GO:0005768(endosome);GO:0070062(extracellular exosome);GO:0043312(neutrophil degranulation);GO:0035579(specific granule membrane);GO:0035577(azurophil granule membrane);GO:0016049(cell growth);GO:0101003(ficolin-1-rich granule membrane);GO:0032947(protein complex scaffold);GO:0007050(cell cycle arrest);GO:0016241(regulation of macroautophagy);GO:0007032(endosome organization);GO:0032418(lysosome localization);GO:0034613(cellular protein localization);GO:0051020(GTPase binding);GO:0010872(regulation of cholesterol esterification);GO:0010874(regulation of cholesterol efflux);GO:0060620(regulation of cholesterol import);GO:0060620(regulation of cholesterol import)","04150(mTOR signaling pathway);04150(mTOR signaling pathway)","K20397","NA","late endosomal/lysosomal adaptor, MAPK and MTOR activator 1 [Source:HGNC Symbol;Acc:HGNC:26068]",{"v":11.1363629481641,"d":"11.14"},{"v":25.0786723264939,"d":"25.08"},{"v":0.444057117664849,"d":"0.44"},{"v":-1.17118283706884,"d":"-1.17"},{"v":0.0843756077157157,"d":"0.08"},{"v":0.806690420475253,"d":"0.81"},"down","no"]
["MSTRG.1202","PRDX6","ENST00000340385;ENST00000460950;ENST00000470017","GO:0005737(cytoplasm);GO:0005623(cell);GO:0005634(nucleus);GO:0016020(membrane);GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0016787(hydrolase activity);GO:0006629(lipid metabolic process);GO:0016042(lipid catabolic process);GO:0005829(cytosol);GO:0045454(cell redox homeostasis);GO:0005515(protein binding);GO:0003824(catalytic activity);GO:0008152(metabolic process);GO:0048471(perinuclear region of cytoplasm);GO:0005615(extracellular space);GO:0031410(cytoplasmic vesicle);GO:0098869(cellular oxidant detoxification);GO:0004623(phospholipase A2 activity);GO:0005764(lysosome);GO:0005576(extracellular region);GO:0004601(peroxidase activity);GO:0051920(peroxiredoxin activity);GO:0016209(antioxidant activity);GO:0045296(cadherin binding);GO:0070062(extracellular exosome);GO:0043312(neutrophil degranulation);GO:0035578(azurophil granule lumen);GO:0034599(cellular response to oxidative stress);GO:0031625(ubiquitin protein ligase binding);GO:0042803(protein homodimerization activity);GO:0004602(glutathione peroxidase activity);GO:0047499(calcium-independent phospholipase A2 activity);GO:0006979(response to oxidative stress);GO:0042744(hydrogen peroxide catabolic process);GO:0046475(glycerophospholipid catabolic process);GO:0048026(positive regulation of mRNA splicing, via spliceosome);GO:0048026(positive regulation of mRNA splicing, via spliceosome)","NA","NA","NA","peroxiredoxin 6 [Source:HGNC Symbol;Acc:HGNC:16753]",{"v":18.163426182932,"d":"18.16"},{"v":40.8543610215463,"d":"40.85"},{"v":0.444589652824401,"d":"0.44"},{"v":-1.16945372275421,"d":"-1.17"},{"v":0.0844070694069772,"d":"0.08"},{"v":0.806690420475253,"d":"0.81"},"down","no"]
["MSTRG.14706","TOPORS","ENST00000360538","GO:0043066(negative regulation of apoptotic process);GO:0005634(nucleus);GO:0016607(nuclear speck);GO:0046872(metal ion binding);GO:0005654(nucleoplasm);GO:0016740(transferase activity);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0006974(cellular response to DNA damage stimulus);GO:0006511(ubiquitin-dependent protein catabolic process);GO:0003823(antigen binding);GO:0016925(protein sumoylation);GO:0004842(ubiquitin-protein transferase activity);GO:0043161(proteasome-mediated ubiquitin-dependent protein catabolic process);GO:0016605(PML body);GO:0034504(protein localization to nucleus);GO:0051443(positive regulation of ubiquitin-protein transferase activity);GO:0061630(ubiquitin protein ligase activity);GO:0000209(protein polyubiquitination);GO:0008630(intrinsic apoptotic signaling pathway in response to DNA damage);GO:0000922(spindle pole);GO:0051457(maintenance of protein location in nucleus);GO:0000151(ubiquitin ligase complex);GO:0044547(DNA topoisomerase binding);GO:0030496(midbody);GO:0005814(centriole);GO:0036064(ciliary basal body);GO:0019789(SUMO transferase activity);GO:0005868(cytoplasmic dynein complex);GO:0070936(protein K48-linked ubiquitination);GO:0046548(retinal rod cell development);GO:0006513(protein monoubiquitination);GO:0010842(retina layer formation);GO:0035845(photoreceptor cell outer segment organization);GO:0042127(regulation of cell proliferation);GO:0042771(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator);GO:0045893(positive regulation of transcription, DNA-templated);GO:0046549(retinal cone cell development);GO:0000930(gamma-tubulin complex);GO:0032391(photoreceptor connecting cilium)","NA","NA","NA","TOP1 binding arginine/serine rich protein [Source:HGNC Symbol;Acc:HGNC:21653]",{"v":5.769872,"d":"5.77"},{"v":12.988588,"d":"12.99"},{"v":0.444226270014878,"d":"0.44"},{"v":-1.1706333834533,"d":"-1.17"},{"v":0.084532650526891,"d":"0.08"},{"v":0.807249942620794,"d":"0.81"},"down","no"]
["MSTRG.10992","NT5DC2","ENST00000466112;ENST00000307076;ENST00000479024;ENST00000462261;ENST00000422318;ENST00000486792;ENST00000492555;ENST00000471522;ENST00000478091;ENST00000490681","GO:0046872(metal ion binding);GO:0016787(hydrolase activity);GO:0016311(dephosphorylation);GO:0008253(5'-nucleotidase activity);GO:0008253(5'-nucleotidase activity)","NA","NA","NA","5'-nucleotidase domain containing 2 [Source:HGNC Symbol;Acc:HGNC:25717]",{"v":1.13937443674507,"d":"1.14"},{"v":0.512967988768807,"d":"0.51"},{"v":2.22114140003107,"d":"2.22"},{"v":1.15130123918392,"d":"1.15"},{"v":0.0846144059694319,"d":"0.08"},{"v":0.807390393568858,"d":"0.81"},"up","no"]
["MSTRG.13912","THAP5;PNPLA8","ENST00000415914;ENST00000257694;ENST00000462466;ENST00000483879;ENST00000412935;ENST00000438865;ENST00000484452;ENST00000422087;ENST00000426128;ENST00000313516;ENST00000489738;ENST00000453085;ENST00000493722;ENST00000436062;ENST00000453144","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0007049(cell cycle);GO:0002020(protease binding);GO:0045786(negative regulation of cell cycle);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005524(ATP binding);GO:0016787(hydrolase activity);GO:0005794(Golgi apparatus);GO:0006629(lipid metabolic process);GO:0008152(metabolic process);GO:0016042(lipid catabolic process);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0006631(fatty acid metabolic process);GO:0000139(Golgi membrane);GO:0048471(perinuclear region of cytoplasm);GO:0005777(peroxisome);GO:0005778(peroxisomal membrane);GO:0005622(intracellular);GO:0008219(cell death);GO:0001516(prostaglandin biosynthetic process);GO:0019369(arachidonic acid metabolic process);GO:0004623(phospholipase A2 activity);GO:0036151(phosphatidylcholine acyl-chain remodeling);GO:0036152(phosphatidylethanolamine acyl-chain remodeling);GO:0043651(linoleic acid metabolic process);GO:0004622(lysophospholipase activity);GO:0034638(phosphatidylcholine catabolic process);GO:0047499(calcium-independent phospholipase A2 activity);GO:0046338(phosphatidylethanolamine catabolic process);GO:0050482(arachidonic acid secretion);GO:0050482(arachidonic acid secretion)","NA","NA","NA","THAP domain containing 5 [Source:HGNC Symbol;Acc:HGNC:23188];patatin like phospholipase domain containing 8 [Source:HGNC Symbol;Acc:HGNC:28900]",{"v":1.26205331343284,"d":"1.26"},{"v":2.85100611433218,"d":"2.85"},{"v":0.442669451702829,"d":"0.44"},{"v":-1.17569827735284,"d":"-1.18"},{"v":0.084699244485105,"d":"0.08"},{"v":0.807560017489814,"d":"0.81"},"down","no"]
["MSTRG.7292","TIMP2;CEP295NL","ENST00000262768;ENST00000592761;ENST00000586713;ENST00000322630;ENST00000536189;ENST00000586057","GO:0005576(extracellular region);GO:0008191(metalloendopeptidase inhibitor activity);GO:0010951(negative regulation of endopeptidase activity);GO:0046872(metal ion binding);GO:0008270(zinc ion binding);GO:0005515(protein binding);GO:0005615(extracellular space);GO:0030414(peptidase inhibitor activity);GO:0010466(negative regulation of peptidase activity);GO:0005178(integrin binding);GO:0007417(central nervous system development);GO:0007568(aging);GO:0008285(negative regulation of cell proliferation);GO:0032487(regulation of Rap protein signal transduction);GO:0034097(response to cytokine);GO:0042493(response to drug);GO:0043410(positive regulation of MAPK cascade);GO:0045666(positive regulation of neuron differentiation);GO:0045762(positive regulation of adenylate cyclase activity);GO:0045861(negative regulation of proteolysis);GO:0045930(negative regulation of mitotic cell cycle);GO:0046580(negative regulation of Ras protein signal transduction);GO:0009986(cell surface);GO:0030426(growth cone);GO:0043005(neuron projection);GO:0043025(neuronal cell body);GO:0070062(extracellular exosome);GO:0031012(extracellular matrix);GO:0043312(neutrophil degranulation);GO:0005578(proteinaceous extracellular matrix);GO:0002020(protease binding);GO:1904813(ficolin-1-rich granule lumen);GO:0035580(specific granule lumen);GO:1904724(tertiary granule lumen);GO:0022617(extracellular matrix disassembly);GO:0004857(enzyme inhibitor activity);GO:0009725(response to hormone);GO:1905049(negative regulation of metallopeptidase activity);GO:0051045(negative regulation of membrane protein ectodomain proteolysis);GO:0042995(cell projection);GO:0005929(cilium);GO:0031514(motile cilium);GO:0051045(negative regulation of membrane protein ectodomain proteolysis)","NA","NA","NA","TIMP metallopeptidase inhibitor 2 [Source:HGNC Symbol;Acc:HGNC:11821];CEP295 N-terminal like [Source:HGNC Symbol;Acc:HGNC:44659]",{"v":11.3649924041255,"d":"11.36"},{"v":5.24467302892713,"d":"5.24"},{"v":2.1669591872442,"d":"2.17"},{"v":1.11567198180497,"d":"1.12"},{"v":0.0848059833748415,"d":"0.08"},{"v":0.807938015664431,"d":"0.81"},"up","no"]
["MSTRG.696","LRRC8B","ENST00000640258;ENST00000439853;ENST00000358200","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0006810(transport);GO:0005737(cytoplasm);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0006811(ion transport);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0007165(signal transduction);GO:0055085(transmembrane transport);GO:0005225(volume-sensitive anion channel activity);GO:0044070(regulation of anion transport);GO:0034702(ion channel complex);GO:0098656(anion transmembrane transport);GO:0098656(anion transmembrane transport)","NA","NA","NA","leucine rich repeat containing 8 family member B [Source:HGNC Symbol;Acc:HGNC:30692]",{"v":0.8089070349446,"d":"0.81"},{"v":0.368598511384391,"d":"0.37"},{"v":2.19454775307282,"d":"2.19"},{"v":1.133923663395,"d":"1.13"},{"v":0.0849179280315757,"d":"0.08"},{"v":0.80836497182311,"d":"0.81"},"up","no"]
["MSTRG.8417","LILRB2","ENST00000314446;ENST00000391749;ENST00000493242;ENST00000434421;ENST00000455108;ENST00000471216;ENST00000391748;ENST00000391746","GO:0005615(extracellular space);GO:0005737(cytoplasm);GO:0032755(positive regulation of interleukin-6 production);GO:0071222(cellular response to lipopolysaccharide);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005515(protein binding);GO:0002376(immune system process);GO:0002250(adaptive immune response);GO:0050776(regulation of immune response);GO:0005886(plasma membrane);GO:0005887(integral component of plasma membrane);GO:0043312(neutrophil degranulation);GO:0070821(tertiary granule membrane);GO:0009986(cell surface);GO:0006955(immune response);GO:0007267(cell-cell signaling);GO:0004872(receptor activity);GO:0007166(cell surface receptor signaling pathway);GO:0101003(ficolin-1-rich granule membrane);GO:0045591(positive regulation of regulatory T cell differentiation);GO:0042288(MHC class I protein binding);GO:0006968(cellular defense response);GO:0007165(signal transduction);GO:0042102(positive regulation of T cell proliferation);GO:2001198(regulation of dendritic cell differentiation);GO:0050777(negative regulation of immune response);GO:0050839(cell adhesion molecule binding);GO:0002774(Fc receptor mediated inhibitory signaling pathway);GO:0034113(heterotypic cell-cell adhesion);GO:0002645(positive regulation of tolerance induction);GO:0002666(positive regulation of T cell tolerance induction);GO:0002767(immune response-inhibiting cell surface receptor signaling pathway);GO:0042130(negative regulation of T cell proliferation);GO:0051926(negative regulation of calcium ion transport);GO:0008157(protein phosphatase 1 binding);GO:0023029(MHC class Ib protein binding);GO:0032396(inhibitory MHC class I receptor activity);GO:0002578(negative regulation of antigen processing and presentation);GO:0002578(negative regulation of antigen processing and presentation)","04380(Osteoclast differentiation);04380(Osteoclast differentiation)","K06512","NA","leukocyte immunoglobulin like receptor B2 [Source:HGNC Symbol;Acc:HGNC:6606]",{"v":23.8028231454068,"d":"23.80"},{"v":53.4347287015748,"d":"53.43"},{"v":0.445456049348395,"d":"0.45"},{"v":-1.16664499875192,"d":"-1.17"},{"v":0.0850203727533136,"d":"0.09"},{"v":0.808560229920388,"d":"0.81"},"down","no"]
["MSTRG.2988","APLP2","MSTRG.2988.3;ENST00000263574;ENST00000338167;ENST00000528499;ENST00000529483;ENST00000533195;ENST00000529235;ENST00000529701;ENST00000532456;ENST00000526330;ENST00000527702;ENST00000533713;ENST00000278756;ENST00000461918;ENST00000534001;ENST00000534582;ENST00000345598;ENST00000530493;ENST00000525604;ENST00000530132;ENST00000525215;ENST00000533616;ENST00000533860","GO:0008201(heparin binding);GO:0046914(transition metal ion binding);GO:0005634(nucleus);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0003677(DNA binding);GO:0004867(serine-type endopeptidase inhibitor activity);GO:0010951(negative regulation of endopeptidase activity);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0007186(G-protein coupled receptor signaling pathway);GO:0030414(peptidase inhibitor activity);GO:0010466(negative regulation of peptidase activity);GO:0042802(identical protein binding);GO:0070062(extracellular exosome);GO:0044267(cellular protein metabolic process);GO:0043687(post-translational protein modification);GO:0002576(platelet degranulation);GO:0005788(endoplasmic reticulum lumen);GO:0031092(platelet alpha granule membrane);GO:0031092(platelet alpha granule membrane)","NA","NA","NA","amyloid beta precursor like protein 2 [Source:HGNC Symbol;Acc:HGNC:598]",{"v":20.4468094263857,"d":"20.45"},{"v":45.8794394447725,"d":"45.88"},{"v":0.445663889398618,"d":"0.45"},{"v":-1.16597202578351,"d":"-1.17"},{"v":0.0850901930167355,"d":"0.09"},{"v":0.808560229920388,"d":"0.81"},"down","no"]
["ENSG00000082458","DLG3","ENST00000374355;ENST00000461646;ENST00000542398;ENST00000494493;ENST00000489733;ENST00000466140","GO:0034220(ion transmembrane transport);GO:0005515(protein binding);GO:0005615(extracellular space);GO:0005886(plasma membrane);GO:0005829(cytosol);GO:0007399(nervous system development);GO:0008285(negative regulation of cell proliferation);GO:0016323(basolateral plasma membrane);GO:0019902(phosphatase binding);GO:0010923(negative regulation of phosphatase activity);GO:0046037(GMP metabolic process);GO:0046710(GDP metabolic process);GO:0007268(chemical synaptic transmission);GO:0019900(kinase binding);GO:0015276(ligand-gated ion channel activity);GO:0014069(postsynaptic density);GO:0008328(ionotropic glutamate receptor complex);GO:0004385(guanylate kinase activity);GO:0035255(ionotropic glutamate receptor binding);GO:0045197(establishment or maintenance of epithelial cell apical/basal polarity);GO:0097120(receptor localization to synapse);GO:0043113(receptor clustering);GO:0045211(postsynaptic membrane);GO:0008022(protein C-terminus binding);GO:0019903(protein phosphatase binding);GO:0019904(protein domain specific binding);GO:0030165(PDZ domain binding);GO:0031625(ubiquitin protein ligase binding);GO:0001736(establishment of planar polarity);GO:0005737(cytoplasm);GO:0005911(cell-cell junction);GO:0005923(bicellular tight junction);GO:0030426(growth cone);GO:0032281(AMPA glutamate receptor complex);GO:0043025(neuronal cell body);GO:0043198(dendritic shaft);GO:0045202(synapse);GO:0045202(synapse)","04390(Hippo signaling pathway);04530(Tight junction);05165(Human papillomavirus infection);05165(Human papillomavirus infection)","K21098","NA","discs large MAGUK scaffold protein 3 [Source:HGNC Symbol;Acc:HGNC:2902]",{"v":1.03263707011729,"d":"1.03"},{"v":0.471826003952065,"d":"0.47"},{"v":2.18859719783948,"d":"2.19"},{"v":1.13000645696172,"d":"1.13"},{"v":0.0851398747333543,"d":"0.09"},{"v":0.808560229920388,"d":"0.81"},"up","no"]
["MSTRG.7155","KCNJ2-AS1","ENST00000590966","NA","NA","NA","NA","KCNJ2 antisense RNA 1 (head to head) [Source:HGNC Symbol;Acc:HGNC:43720]",{"v":0.375026,"d":"0.38"},{"v":0.886259,"d":"0.89"},{"v":0.423156210543419,"d":"0.42"},{"v":-1.24073775406231,"d":"-1.24"},{"v":0.0852397158442197,"d":"0.09"},{"v":0.808870495032383,"d":"0.81"},"down","no"]
["MSTRG.2513","VEGFB","ENST00000309422;ENST00000426086;ENST00000543462","GO:0016020(membrane);GO:0008083(growth factor activity);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0005615(extracellular space);GO:0008201(heparin binding);GO:0002576(platelet degranulation);GO:0031093(platelet alpha granule lumen);GO:0048010(vascular endothelial growth factor receptor signaling pathway);GO:0051781(positive regulation of cell division);GO:0001525(angiogenesis);GO:0001666(response to hypoxia);GO:0001938(positive regulation of endothelial cell proliferation);GO:0045766(positive regulation of angiogenesis);GO:0050930(induction of positive chemotaxis);GO:0060754(positive regulation of mast cell chemotaxis);GO:0042803(protein homodimerization activity);GO:0043183(vascular endothelial growth factor receptor 1 binding);GO:0043184(vascular endothelial growth factor receptor 2 binding);GO:0046982(protein heterodimerization activity);GO:0006493(protein O-linked glycosylation);GO:0007507(heart development);GO:0042493(response to drug);GO:0060048(cardiac muscle contraction);GO:0060976(coronary vasculature development);GO:0005622(intracellular);GO:0005622(intracellular)","04014(Ras signaling pathway);04015(Rap1 signaling pathway);04010(MAPK signaling pathway);04151(PI3K-Akt signaling pathway);04060(Cytokine-cytokine receptor interaction);04510(Focal adhesion);04926(Relaxin signaling pathway);05200(Pathways in cancer);04933(AGE-RAGE signaling pathway in diabetic complications);04933(AGE-RAGE signaling pathway in diabetic complications)","K16858","NA","vascular endothelial growth factor B [Source:HGNC Symbol;Acc:HGNC:12681]",{"v":6.63035430809061,"d":"6.63"},{"v":3.04407997799353,"d":"3.04"},{"v":2.17811435836877,"d":"2.18"},{"v":1.12307970241126,"d":"1.12"},{"v":0.0853070368915149,"d":"0.09"},{"v":0.808871919880018,"d":"0.81"},"up","no"]
["MSTRG.6251","CHMP1A","ENST00000535997;ENST00000547687;ENST00000397901;ENST00000550102;ENST00000548650;ENST00000547614;ENST00000551981;ENST00000549139;ENST00000550872;ENST00000549328","GO:0006810(transport);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0015031(protein transport);GO:0016192(vesicle-mediated transport);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0051301(cell division);GO:0042803(protein homodimerization activity);GO:0005515(protein binding);GO:0006508(proteolysis);GO:0007049(cell cycle);GO:0007034(vacuolar transport);GO:0005815(microtubule organizing center);GO:0042802(identical protein binding);GO:0005768(endosome);GO:0070062(extracellular exosome);GO:0036258(multivesicular body assembly);GO:0039702(viral budding via host ESCRT complex);GO:0012505(endomembrane system);GO:0005769(early endosome);GO:0010008(endosome membrane);GO:0007076(mitotic chromosome condensation);GO:0000815(ESCRT III complex);GO:0016363(nuclear matrix);GO:0019904(protein domain specific binding);GO:0045892(negative regulation of transcription, DNA-templated);GO:0000794(condensed nuclear chromosome);GO:0008270(zinc ion binding);GO:0008237(metallopeptidase activity);GO:0007080(mitotic metaphase plate congression);GO:0010824(regulation of centrosome duplication);GO:0000920(cell separation after cytokinesis);GO:0006997(nucleus organization);GO:1901673(regulation of mitotic spindle assembly);GO:1904903(ESCRT III complex disassembly);GO:0016458(gene silencing);GO:0045014(negative regulation of transcription by glucose);GO:0045014(negative regulation of transcription by glucose)","04144(Endocytosis);04217(Necroptosis);04217(Necroptosis)","K12197","NA","charged multivesicular body protein 1A [Source:HGNC Symbol;Acc:HGNC:8740]",{"v":8.6564505963217,"d":"8.66"},{"v":3.98771396726933,"d":"3.99"},{"v":2.17078021828366,"d":"2.17"},{"v":1.11821366697422,"d":"1.12"},{"v":0.0854392006441094,"d":"0.09"},{"v":0.809061147317794,"d":"0.81"},"up","no"]
["MSTRG.8936","IGKV4-1","ENST00000390243","GO:0016020(membrane);GO:0005886(plasma membrane);GO:0005576(extracellular region);GO:0006508(proteolysis);GO:0006955(immune response);GO:0002376(immune system process);GO:0002377(immunoglobulin production);GO:0003823(antigen binding);GO:0002250(adaptive immune response);GO:0004252(serine-type endopeptidase activity);GO:0006898(receptor-mediated endocytosis);GO:0006956(complement activation);GO:0006958(complement activation, classical pathway);GO:0030449(regulation of complement activation);GO:0038095(Fc-epsilon receptor signaling pathway);GO:0038096(Fc-gamma receptor signaling pathway involved in phagocytosis);GO:0050776(regulation of immune response);GO:0050900(leukocyte migration);GO:0070062(extracellular exosome);GO:0072562(blood microparticle)","NA","NA","NA","immunoglobulin kappa variable 4-1 [Source:HGNC Symbol;Acc:HGNC:5834]",{"v":10.578842,"d":"10.58"},{"v":4.796724,"d":"4.80"},{"v":2.20543062306691,"d":"2.21"},{"v":1.14106037782683,"d":"1.14"},{"v":0.085461366831775,"d":"0.09"},{"v":0.809061147317794,"d":"0.81"},"up","no"]
["ENSG00000138346","DNA2","ENST00000358410;ENST00000399180;ENST00000551118;ENST00000478029","GO:0005634(nucleus);GO:0005739(mitochondrion);GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0016787(hydrolase activity);GO:0004386(helicase activity);GO:0032508(DNA duplex unwinding);GO:0003677(DNA binding);GO:0003824(catalytic activity);GO:0008152(metabolic process);GO:0006281(DNA repair);GO:0006974(cellular response to DNA damage stimulus);GO:0004519(endonuclease activity);GO:0004518(nuclease activity);GO:0051536(iron-sulfur cluster binding);GO:0051539(4 iron, 4 sulfur cluster binding);GO:0006260(DNA replication);GO:0005515(protein binding);GO:0005654(nucleoplasm);GO:0000784(nuclear chromosome, telomeric region);GO:0016887(ATPase activity);GO:0006284(base-excision repair);GO:1901796(regulation of signal transduction by p53 class mediator);GO:0045740(positive regulation of DNA replication);GO:0000731(DNA synthesis involved in DNA repair);GO:0000732(strand displacement);GO:0090656(t-circle formation);GO:0043142(single-stranded DNA-dependent ATPase activity);GO:0042645(mitochondrial nucleoid);GO:0003678(DNA helicase activity);GO:0000723(telomere maintenance);GO:0032201(telomere maintenance via semi-conservative replication);GO:1902990(mitotic telomere maintenance via semi-conservative replication);GO:0043139(5'-3' DNA helicase activity);GO:0044806(G-quadruplex DNA unwinding);GO:0016890(site-specific endodeoxyribonuclease activity, specific for altered base);GO:0017108(5'-flap endonuclease activity);GO:0043137(DNA replication, removal of RNA primer);GO:0005760(gamma DNA polymerase complex);GO:0000076(DNA replication checkpoint);GO:0000729(DNA double-strand break processing);GO:0006264(mitochondrial DNA replication);GO:0033567(DNA replication, Okazaki fragment processing);GO:0043504(mitochondrial DNA repair);GO:0090305(nucleic acid phosphodiester bond hydrolysis);GO:0090305(nucleic acid phosphodiester bond hydrolysis)","03030(DNA replication);03030(DNA replication)","K10742","EC:3.6.4.12","DNA replication helicase/nuclease 2 [Source:HGNC Symbol;Acc:HGNC:2939]",{"v":0.354290132319704,"d":"0.35"},{"v":0.156330354016848,"d":"0.16"},{"v":2.2662913709101,"d":"2.27"},{"v":1.18033335645573,"d":"1.18"},{"v":0.085636738994128,"d":"0.09"},{"v":0.810084533360007,"d":"0.81"},"up","no"]
["MSTRG.1965","GSTO1","ENST00000369713;ENST00000493946;ENST00000369710;ENST00000539281;ENST00000470554;ENST00000432659;ENST00000445155","GO:0010880(regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum);GO:0010881(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion);GO:0005737(cytoplasm);GO:0016740(transferase activity);GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0008152(metabolic process);GO:0005829(cytosol);GO:0005515(protein binding);GO:0098869(cellular oxidant detoxification);GO:0004364(glutathione transferase activity);GO:0070062(extracellular exosome);GO:0006749(glutathione metabolic process);GO:0035722(interleukin-12-mediated signaling pathway);GO:0071243(cellular response to arsenic-containing substance);GO:1901687(glutathione derivative biosynthetic process);GO:0060315(negative regulation of ryanodine-sensitive calcium-release channel activity);GO:0032259(methylation);GO:0042178(xenobiotic catabolic process);GO:0060316(positive regulation of ryanodine-sensitive calcium-release channel activity);GO:0045174(glutathione dehydrogenase (ascorbate) activity);GO:0050610(methylarsonate reductase activity);GO:0009407(toxin catabolic process);GO:0014810(positive regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion);GO:0019852(L-ascorbic acid metabolic process);GO:0019852(L-ascorbic acid metabolic process)","00480(Glutathione metabolism);00980(Metabolism of xenobiotics by cytochrome P450);00982(Drug metabolism - cytochrome P450);00983(Drug metabolism - other enzymes);05200(Pathways in cancer);05204(Chemical carcinogenesis);05225(Hepatocellular carcinoma);05418(Fluid shear stress and atherosclerosis);01524(Platinum drug resistance);01524(Platinum drug resistance)","K00799","EC:2.5.1.18","glutathione S-transferase omega 1 [Source:HGNC Symbol;Acc:HGNC:13312]",{"v":4.50406954760497,"d":"4.50"},{"v":10.1310246528681,"d":"10.13"},{"v":0.444581836678274,"d":"0.44"},{"v":-1.16947908639978,"d":"-1.17"},{"v":0.0857140460812434,"d":"0.09"},{"v":0.810179390039508,"d":"0.81"},"down","no"]
["MSTRG.10732","NR1D2","ENST00000312521;ENST00000468700;ENST00000492552;ENST00000383773;ENST00000472780","GO:0005634(nucleus);GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0005654(nucleoplasm);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0043565(sequence-specific DNA binding);GO:0005515(protein binding);GO:0003707(steroid hormone receptor activity);GO:0030522(intracellular receptor signaling pathway);GO:0043401(steroid hormone mediated signaling pathway);GO:0048511(rhythmic process);GO:0045893(positive regulation of transcription, DNA-templated);GO:0000980(RNA polymerase II distal enhancer sequence-specific DNA binding);GO:0001046(core promoter sequence-specific DNA binding);GO:0001206(transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0019216(regulation of lipid metabolic process);GO:0042752(regulation of circadian rhythm);GO:0045892(negative regulation of transcription, DNA-templated);GO:0050727(regulation of inflammatory response);GO:0055088(lipid homeostasis);GO:2000505(regulation of energy homeostasis);GO:2001014(regulation of skeletal muscle cell differentiation);GO:0006367(transcription initiation from RNA polymerase II promoter);GO:0004879(RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding);GO:0004879(RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding)","NA","NA","NA","nuclear receptor subfamily 1 group D member 2 [Source:HGNC Symbol;Acc:HGNC:7963]",{"v":3.09867641769759,"d":"3.10"},{"v":1.43024171924399,"d":"1.43"},{"v":2.16654036587292,"d":"2.17"},{"v":1.11539311641692,"d":"1.12"},{"v":0.0860083473595075,"d":"0.09"},{"v":0.812323544237796,"d":"0.81"},"up","no"]
["MSTRG.1344","MAPKAPK2","MSTRG.1344.3;ENST00000367103;ENST00000294981;ENST00000479009;ENST00000493447","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0005654(nucleoplasm);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0005813(centrosome);GO:0005515(protein binding);GO:0006974(cellular response to DNA damage stimulus);GO:0006954(inflammatory response);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0043488(regulation of mRNA stability);GO:0032496(response to lipopolysaccharide);GO:0005516(calmodulin binding);GO:0004871(signal transducer activity);GO:0048010(vascular endothelial growth factor receptor signaling pathway);GO:0031572(G2 DNA damage checkpoint);GO:0035924(cellular response to vascular endothelial growth factor stimulus);GO:0006950(response to stress);GO:0018105(peptidyl-serine phosphorylation);GO:1900034(regulation of cellular response to heat);GO:0000187(activation of MAPK activity);GO:0034097(response to cytokine);GO:0002224(toll-like receptor signaling pathway);GO:0007265(Ras protein signal transduction);GO:0032680(regulation of tumor necrosis factor production);GO:0070935(3'-UTR-mediated mRNA stabilization);GO:0006691(leukotriene metabolic process);GO:0000165(MAPK cascade);GO:0004683(calmodulin-dependent protein kinase activity);GO:0009931(calcium-dependent protein serine/threonine kinase activity);GO:0051019(mitogen-activated protein kinase binding);GO:0032675(regulation of interleukin-6 production);GO:0044351(macropinocytosis);GO:0046777(protein autophosphorylation);GO:0038066(p38MAPK cascade);GO:0042535(positive regulation of tumor necrosis factor biosynthetic process);GO:0048255(mRNA stabilization);GO:0048839(inner ear development);GO:0048839(inner ear development)","04010(MAPK signaling pathway);04370(VEGF signaling pathway);04218(Cellular senescence);04722(Neurotrophin signaling pathway);05203(Viral carcinogenesis);05167(Kaposi's sarcoma-associated herpesvirus infection);05167(Kaposi's sarcoma-associated herpesvirus infection)","K04443","EC:2.7.11.1","mitogen-activated protein kinase-activated protein kinase 2 [Source:HGNC Symbol;Acc:HGNC:6887]",{"v":10.1105662006195,"d":"10.11"},{"v":22.6476732911604,"d":"22.65"},{"v":0.44642847283415,"d":"0.45"},{"v":-1.16349905090429,"d":"-1.16"},{"v":0.0860769759855517,"d":"0.09"},{"v":0.812334596252362,"d":"0.81"},"down","no"]
["MSTRG.13540","CREB5","ENST00000396298;ENST00000357727;ENST00000498316;ENST00000468813;ENST00000484383;ENST00000482692;ENST00000461921;ENST00000396299;ENST00000426500;ENST00000468391","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0045893(positive regulation of transcription, DNA-templated);GO:0005515(protein binding);GO:0070062(extracellular exosome);GO:0006366(transcription from RNA polymerase II promoter);GO:0006366(transcription from RNA polymerase II promoter)","04668(TNF signaling pathway);04024(cAMP signaling pathway);04022(cGMP - PKG signaling pathway);04151(PI3K-Akt signaling pathway);04152(AMPK signaling pathway);04911(Insulin secretion);04922(Glucagon signaling pathway);04915(Estrogen signaling pathway);04926(Relaxin signaling pathway);04918(Thyroid hormone synthesis);04925(Aldosterone synthesis and secretion);04927(Cortisol synthesis and secretion);04261(Adrenergic signaling in cardiomyocytes);04962(Vasopressin-regulated water reabsorption);04725(Cholinergic synapse);04728(Dopaminergic synapse);04211(Longevity regulating pathway - mammal);05203(Viral carcinogenesis);05215(Prostate cancer);05016(Huntington's disease);05030(Cocaine addiction);05031(Amphetamine addiction);05034(Alcoholism);04931(Insulin resistance);05161(Hepatitis B);05165(Human papillomavirus infection);05165(Human papillomavirus infection)","K09047","NA","cAMP responsive element binding protein 5 [Source:HGNC Symbol;Acc:HGNC:16844]",{"v":2.05638567740278,"d":"2.06"},{"v":4.60886135557649,"d":"4.61"},{"v":0.446180850051967,"d":"0.45"},{"v":-1.16429950001426,"d":"-1.16"},{"v":0.086158245098918,"d":"0.09"},{"v":0.812422394843833,"d":"0.81"},"down","no"]
["ENSG00000196227","FAM217B","ENST00000360816;ENST00000421092;ENST00000358293","GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0005654(nucleoplasm)","NA","NA","NA","family with sequence similarity 217 member B [Source:HGNC Symbol;Acc:HGNC:16170]",{"v":1.18807302310727,"d":"1.19"},{"v":2.6751354277663,"d":"2.68"},{"v":0.444116963491188,"d":"0.44"},{"v":-1.17098841735126,"d":"-1.17"},{"v":0.0862212108130227,"d":"0.09"},{"v":0.812422394843833,"d":"0.81"},"down","no"]
["MSTRG.714","TMED5","ENST00000370282;ENST00000479918;ENST00000370280;ENST00000370290;ENST00000483033","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0015031(protein transport);GO:0005794(Golgi apparatus);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005515(protein binding);GO:0090161(Golgi ribbon formation);GO:0005793(endoplasmic reticulum-Golgi intermediate compartment);GO:0033116(endoplasmic reticulum-Golgi intermediate compartment membrane);GO:0070971(endoplasmic reticulum exit site);GO:0005801(cis-Golgi network);GO:0005801(cis-Golgi network)","NA","NA","NA","transmembrane p24 trafficking protein 5 [Source:HGNC Symbol;Acc:HGNC:24251]",{"v":2.21119999384485,"d":"2.21"},{"v":4.95682955014327,"d":"4.96"},{"v":0.44609159372465,"d":"0.45"},{"v":-1.16458813307049,"d":"-1.16"},{"v":0.0864951800675975,"d":"0.09"},{"v":0.813698928375092,"d":"0.81"},"down","no"]
["ENSG00000254789","AC073172.1","ENST00000533082;ENST00000636967","NA","NA","NA","NA",null,{"v":1.12514427144536,"d":"1.13"},{"v":2.61105721856639,"d":"2.61"},{"v":0.430915210683558,"d":"0.43"},{"v":-1.21452407049237,"d":"-1.21"},{"v":0.0864991707132882,"d":"0.09"},{"v":0.813698928375092,"d":"0.81"},"down","no"]
["MSTRG.11848","RAB33B","ENST00000305626;ENST00000507271","GO:0006810(transport);GO:0016020(membrane);GO:0015031(protein transport);GO:0005525(GTP binding);GO:0000166(nucleotide binding);GO:0003924(GTPase activity);GO:0005794(Golgi apparatus);GO:0000139(Golgi membrane);GO:0006914(autophagy);GO:0005515(protein binding);GO:0070062(extracellular exosome);GO:0005796(Golgi lumen);GO:0006891(intra-Golgi vesicle-mediated transport);GO:2000785(regulation of autophagosome assembly);GO:0048705(skeletal system morphogenesis);GO:0000042(protein targeting to Golgi);GO:1903358(regulation of Golgi organization);GO:0000045(autophagosome assembly);GO:1903434(negative regulation of constitutive secretory pathway);GO:2000156(regulation of retrograde vesicle-mediated transport, Golgi to ER);GO:2000156(regulation of retrograde vesicle-mediated transport, Golgi to ER)","04140(Autophagy - animal);04140(Autophagy - animal)","K07920","NA","RAB33B, member RAS oncogene family [Source:HGNC Symbol;Acc:HGNC:16075]",{"v":1.17164191050119,"d":"1.17"},{"v":2.63710638623707,"d":"2.64"},{"v":0.444290725856163,"d":"0.44"},{"v":-1.17042406810385,"d":"-1.17"},{"v":0.08655940269461,"d":"0.09"},{"v":0.813698928375092,"d":"0.81"},"down","no"]
["ENSG00000075218","GTSE1","ENST00000466510;ENST00000454366;ENST00000479645;ENST00000491863","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0005874(microtubule);GO:0003674(molecular_function);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0043161(proteasome-mediated ubiquitin-dependent protein catabolic process);GO:0005881(cytoplasmic microtubule);GO:0046827(positive regulation of protein export from nucleus);GO:1902749(regulation of cell cycle G2/M phase transition);GO:0050821(protein stabilization);GO:0006977(DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest);GO:0007017(microtubule-based process);GO:1900182(positive regulation of protein localization to nucleus);GO:0030335(positive regulation of cell migration);GO:1904527(negative regulation of microtubule binding);GO:1904527(negative regulation of microtubule binding)","04115(p53 signaling pathway);04115(p53 signaling pathway)","K10129","NA","G2 and S-phase expressed 1 [Source:HGNC Symbol;Acc:HGNC:13698]",{"v":0.389743822960868,"d":"0.39"},{"v":0.16896489533239,"d":"0.17"},{"v":2.30665560555735,"d":"2.31"},{"v":1.20580261899959,"d":"1.21"},{"v":0.0867099548337637,"d":"0.09"},{"v":0.813824506984838,"d":"0.81"},"up","no"]
["MSTRG.12364","PAIP2","ENST00000510409;ENST00000265192;ENST00000510080;ENST00000507415;ENST00000511381;ENST00000394795","GO:0005737(cytoplasm);GO:0005515(protein binding);GO:0006417(regulation of translation);GO:0030371(translation repressor activity);GO:0045947(negative regulation of translational initiation);GO:0003729(mRNA binding);GO:0007283(spermatogenesis);GO:0007613(memory);GO:0017148(negative regulation of translation);GO:1900271(regulation of long-term synaptic potentiation);GO:1900271(regulation of long-term synaptic potentiation)","NA","NA","NA","poly(A) binding protein interacting protein 2 [Source:HGNC Symbol;Acc:HGNC:17970]",{"v":15.5984609145028,"d":"15.60"},{"v":34.870113960418,"d":"34.87"},{"v":0.447330368125812,"d":"0.45"},{"v":-1.16058739230757,"d":"-1.16"},{"v":0.0867407232342599,"d":"0.09"},{"v":0.813824506984838,"d":"0.81"},"down","no"]
["MSTRG.12707","ALDH5A1","ENST00000357578;ENST00000348925;ENST00000479394;ENST00000492697","GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0005739(mitochondrion);GO:0008152(metabolic process);GO:0042803(protein homodimerization activity);GO:0006541(glutamine metabolic process);GO:0005759(mitochondrial matrix);GO:0006650(glycerophospholipid metabolic process);GO:0006006(glucose metabolic process);GO:0009013(succinate-semialdehyde dehydrogenase [NAD(P)+] activity);GO:0009450(gamma-aminobutyric acid catabolic process);GO:0051289(protein homotetramerization);GO:0006749(glutathione metabolic process);GO:0007417(central nervous system development);GO:0006536(glutamate metabolic process);GO:0042135(neurotransmitter catabolic process);GO:0006105(succinate metabolic process);GO:0022904(respiratory electron transport chain);GO:0004777(succinate-semialdehyde dehydrogenase (NAD+) activity);GO:0051287(NAD binding);GO:0006083(acetate metabolic process);GO:0006540(glutamate decarboxylation to succinate);GO:0006681(galactosylceramide metabolic process);GO:0046459(short-chain fatty acid metabolic process);GO:0006678(glucosylceramide metabolic process);GO:0009448(gamma-aminobutyric acid metabolic process);GO:0009791(post-embryonic development);GO:0009791(post-embryonic development)","00650(Butanoate metabolism);00250(Alanine, aspartate and glutamate metabolism);00250(Alanine, aspartate and glutamate metabolism)","K00139","EC:1.2.1.24","aldehyde dehydrogenase 5 family member A1 [Source:HGNC Symbol;Acc:HGNC:408]",{"v":1.26243774660634,"d":"1.26"},{"v":0.578514875294118,"d":"0.58"},{"v":2.1822044696163,"d":"2.18"},{"v":1.12578628657493,"d":"1.13"},{"v":0.0869284180335457,"d":"0.09"},{"v":0.813824506984838,"d":"0.81"},"up","no"]
["MSTRG.1992","DCLRE1A","MSTRG.1992.1","NA","NA","NA","NA",null,{"v":4.563542,"d":"4.56"},{"v":10.561625,"d":"10.56"},{"v":0.432087107807747,"d":"0.43"},{"v":-1.21060590904026,"d":"-1.21"},{"v":0.0869366649738521,"d":"0.09"},{"v":0.813824506984838,"d":"0.81"},"down","no"]
["ENSG00000152990","ADGRA3","ENST00000334304;ENST00000282943;ENST00000499527","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0004930(G-protein coupled receptor activity);GO:0007186(G-protein coupled receptor signaling pathway);GO:0004871(signal transducer activity);GO:0007165(signal transduction);GO:0004888(transmembrane signaling receptor activity);GO:0007166(cell surface receptor signaling pathway);GO:0009897(external side of plasma membrane);GO:0009897(external side of plasma membrane)","NA","NA","NA","adhesion G protein-coupled receptor A3 [Source:HGNC Symbol;Acc:HGNC:13839]",{"v":0.372122570378378,"d":"0.37"},{"v":0.166826895351351,"d":"0.17"},{"v":2.23059099430375,"d":"2.23"},{"v":1.15742600233838,"d":"1.16"},{"v":0.0869954690665549,"d":"0.09"},{"v":0.813824506984838,"d":"0.81"},"up","no"]
["MSTRG.6663","RHOT1","ENST00000333942;ENST00000358365;ENST00000394692;ENST00000354266;ENST00000583994;ENST00000578205;ENST00000580392;ENST00000581031;ENST00000581094;ENST00000581567;ENST00000584692;ENST00000545287;ENST00000582586;ENST00000581148","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005525(GTP binding);GO:0007264(small GTPase mediated signal transduction);GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0016787(hydrolase activity);GO:0005509(calcium ion binding);GO:0003924(GTPase activity);GO:0005739(mitochondrion);GO:0005515(protein binding);GO:0005741(mitochondrial outer membrane);GO:0007005(mitochondrion organization);GO:0005886(plasma membrane);GO:0003674(molecular_function);GO:0005829(cytosol);GO:0051056(regulation of small GTPase mediated signal transduction);GO:0016579(protein deubiquitination);GO:0031307(integral component of mitochondrial outer membrane);GO:0019725(cellular homeostasis);GO:0097345(mitochondrial outer membrane permeabilization);GO:0047497(mitochondrion transport along microtubule);GO:0034640(establishment of mitochondrion localization by microtubule attachment);GO:0046928(regulation of neurotransmitter secretion);GO:1902513(regulation of organelle transport along microtubule);GO:0005622(intracellular);GO:0005622(intracellular)","04137(Mitophagy - animal);04137(Mitophagy - animal)","K07870","EC:3.6.5.-","ras homolog family member T1 [Source:HGNC Symbol;Acc:HGNC:21168]",{"v":1.8256944695543,"d":"1.83"},{"v":4.09894739500942,"d":"4.10"},{"v":0.445405684341578,"d":"0.45"},{"v":-1.16680812472961,"d":"-1.17"},{"v":0.0870433817379956,"d":"0.09"},{"v":0.813824506984838,"d":"0.81"},"down","no"]
["MSTRG.3582","POC1B;GALNT4;POC1B-GALNT4","ENST00000393179;ENST00000529983;ENST00000548715;ENST00000549304;ENST00000313546;ENST00000539190;ENST00000548729;ENST00000549591;ENST00000549035;ENST00000552563;ENST00000546740;ENST00000547496;ENST00000551819;ENST00000546830;ENST00000549504","GO:0005737(cytoplasm);GO:0005856(cytoskeleton);GO:0042995(cell projection);GO:0005515(protein binding);GO:0000922(spindle pole);GO:0005813(centrosome);GO:0060271(cilium assembly);GO:0030030(cell projection organization);GO:0005814(centriole);GO:0001895(retina homeostasis);GO:0036064(ciliary basal body);GO:0008283(cell proliferation);GO:0048471(perinuclear region of cytoplasm);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0046872(metal ion binding);GO:0016740(transferase activity);GO:0030246(carbohydrate binding);GO:0016757(transferase activity, transferring glycosyl groups);GO:0005794(Golgi apparatus);GO:0000139(Golgi membrane);GO:0006486(protein glycosylation);GO:0070062(extracellular exosome);GO:0005975(carbohydrate metabolic process);GO:0016266(O-glycan processing);GO:0004653(polypeptide N-acetylgalactosaminyltransferase activity);GO:0008283(cell proliferation)","00512(Mucin type O-glycan biosynthesis);00512(Mucin type O-glycan biosynthesis)","K00710","EC:2.4.1.41","POC1 centriolar protein B [Source:HGNC Symbol;Acc:HGNC:30836];polypeptide N-acetylgalactosaminyltransferase 4 [Source:HGNC Symbol;Acc:HGNC:4126];POC1B-GALNT4 readthrough [Source:HGNC Symbol;Acc:HGNC:42957]",{"v":0.96658785677536,"d":"0.97"},{"v":2.16583073802406,"d":"2.17"},{"v":0.446289656807254,"d":"0.45"},{"v":-1.16394772375759,"d":"-1.16"},{"v":0.0870458366547476,"d":"0.09"},{"v":0.813824506984838,"d":"0.81"},"down","no"]
["MSTRG.7384","LPIN2","MSTRG.7384.2;MSTRG.7384.1;MSTRG.7384.4;ENST00000581568;ENST00000261596;ENST00000584915;ENST00000584294","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0003713(transcription coactivator activity);GO:0016787(hydrolase activity);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0006629(lipid metabolic process);GO:0005829(cytosol);GO:0008195(phosphatidate phosphatase activity);GO:0016311(dephosphorylation);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0006631(fatty acid metabolic process);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0009062(fatty acid catabolic process);GO:0019432(triglyceride biosynthetic process);GO:0006656(phosphatidylcholine biosynthetic process);GO:0006646(phosphatidylethanolamine biosynthetic process);GO:0006646(phosphatidylethanolamine biosynthetic process)","00561(Glycerolipid metabolism);00564(Glycerophospholipid metabolism);00564(Glycerophospholipid metabolism)","K15728","EC:3.1.3.4","lipin 2 [Source:HGNC Symbol;Acc:HGNC:14450]",{"v":6.03017351696222,"d":"6.03"},{"v":13.466031539707,"d":"13.47"},{"v":0.447806281990442,"d":"0.45"},{"v":-1.15905332790076,"d":"-1.16"},{"v":0.0872335533274496,"d":"0.09"},{"v":0.814313343557551,"d":"0.81"},"down","no"]
["ENSG00000137449","CPEB2","ENST00000538197;ENST00000345451;ENST00000382395;ENST00000507071;ENST00000442003;ENST00000509684;ENST00000382401;ENST00000259997","GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0003730(mRNA 3'-UTR binding);GO:0045182(translation regulator activity);GO:0006417(regulation of translation);GO:0043022(ribosome binding);GO:0045202(synapse);GO:0000900(translation repressor activity, nucleic acid binding);GO:0008135(translation factor activity, RNA binding);GO:0043005(neuron projection);GO:1990124(messenger ribonucleoprotein complex);GO:0043023(ribosomal large subunit binding);GO:0034599(cellular response to oxidative stress);GO:0032869(cellular response to insulin stimulus);GO:0043024(ribosomal small subunit binding);GO:0071243(cellular response to arsenic-containing substance);GO:0071456(cellular response to hypoxia);GO:0005095(GTPase inhibitor activity);GO:0034260(negative regulation of GTPase activity);GO:0006412(translation);GO:0035925(mRNA 3'-UTR AU-rich region binding);GO:2000766(negative regulation of cytoplasmic translation);GO:1900248(negative regulation of cytoplasmic translational elongation);GO:1900248(negative regulation of cytoplasmic translational elongation)","04114(Oocyte meiosis);04914(Progesterone-mediated oocyte maturation);04914(Progesterone-mediated oocyte maturation)","K02602","NA","cytoplasmic polyadenylation element binding protein 2 [Source:HGNC Symbol;Acc:HGNC:21745]",{"v":0.491255552180577,"d":"0.49"},{"v":1.11464703427616,"d":"1.11"},{"v":0.440727456382274,"d":"0.44"},{"v":-1.18204131864262,"d":"-1.18"},{"v":0.0872428986817548,"d":"0.09"},{"v":0.814313343557551,"d":"0.81"},"down","no"]
["MSTRG.11696","PLAC8","MSTRG.11696.1","NA","NA","NA","NA",null,{"v":25.942514,"d":"25.94"},{"v":12.027307,"d":"12.03"},{"v":2.15696780667526,"d":"2.16"},{"v":1.10900464404748,"d":"1.11"},{"v":0.0873676341441991,"d":"0.09"},{"v":0.814313343557551,"d":"0.81"},"up","no"]
["ENSG00000148840","PPRC1","ENST00000278070;ENST00000495914;ENST00000370012;ENST00000489648;ENST00000413464;ENST00000462933","GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0008134(transcription factor binding);GO:0003712(transcription cofactor activity);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0007005(mitochondrion organization);GO:0030374(ligand-dependent nuclear receptor transcription coactivator activity);GO:0001104(RNA polymerase II transcription cofactor activity);GO:0051091(positive regulation of sequence-specific DNA binding transcription factor activity);GO:1903506(regulation of nucleic acid-templated transcription);GO:1903506(regulation of nucleic acid-templated transcription)","NA","NA","NA","peroxisome proliferator-activated receptor gamma, coactivator-related 1 [Source:HGNC Symbol;Acc:HGNC:30025]",{"v":4.54520676324856,"d":"4.55"},{"v":2.10586760541427,"d":"2.11"},{"v":2.15835352211253,"d":"2.16"},{"v":1.10993118680332,"d":"1.11"},{"v":0.0873935512203948,"d":"0.09"},{"v":0.814313343557551,"d":"0.81"},"up","no"]
["ENSG00000173875","ZNF791","ENST00000343325;ENST00000598225;ENST00000597691;ENST00000498389","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0005622(intracellular);GO:0005622(intracellular)","NA","NA","NA","zinc finger protein 791 [Source:HGNC Symbol;Acc:HGNC:26895]",{"v":1.65221036585366,"d":"1.65"},{"v":0.761349943992773,"d":"0.76"},{"v":2.17010637340947,"d":"2.17"},{"v":1.11776576185364,"d":"1.12"},{"v":0.0874362359425272,"d":"0.09"},{"v":0.814313343557551,"d":"0.81"},"up","no"]
["MSTRG.14437","CPNE3","ENST00000517490;ENST00000622183;ENST00000621526;ENST00000517862;ENST00000614678;ENST00000620393;ENST00000517354;ENST00000523469;ENST00000621783;ENST00000517391","GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0004674(protein serine/threonine kinase activity);GO:0005730(nucleolus);GO:0005829(cytosol);GO:0005739(mitochondrion);GO:0006468(protein phosphorylation);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0030054(cell junction);GO:0005544(calcium-dependent phospholipid binding);GO:0005925(focal adhesion);GO:0070062(extracellular exosome);GO:0048306(calcium-dependent protein binding);GO:0030335(positive regulation of cell migration);GO:0043312(neutrophil degranulation);GO:0005215(transporter activity);GO:0016192(vesicle-mediated transport);GO:0030971(receptor tyrosine kinase binding);GO:0035577(azurophil granule membrane);GO:0006629(lipid metabolic process);GO:0071277(cellular response to calcium ion);GO:0071363(cellular response to growth factor stimulus);GO:0038128(ERBB2 signaling pathway);GO:0046474(glycerophospholipid biosynthetic process);GO:0046474(glycerophospholipid biosynthetic process)","NA","NA","NA","copine 3 [Source:HGNC Symbol;Acc:HGNC:2316]",{"v":2.85256384388436,"d":"2.85"},{"v":6.37789442905856,"d":"6.38"},{"v":0.44725792745764,"d":"0.45"},{"v":-1.160821041224,"d":"-1.16"},{"v":0.0875104150306656,"d":"0.09"},{"v":0.814374356877338,"d":"0.81"},"down","no"]
["MSTRG.5450","MCTP2","ENST00000451018;ENST00000456504;MSTRG.5450.2;ENST00000556363;ENST00000557505;ENST00000357742;ENST00000557742;ENST00000543482;ENST00000561608;ENST00000449432","GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0007275(multicellular organism development);GO:0005783(endoplasmic reticulum);GO:0019722(calcium-mediated signaling);GO:0005509(calcium ion binding);GO:0005509(calcium ion binding)","NA","NA","NA","multiple C2 and transmembrane domain containing 2 [Source:HGNC Symbol;Acc:HGNC:25636]",{"v":1.67123601548775,"d":"1.67"},{"v":3.73478422414856,"d":"3.73"},{"v":0.44747859988317,"d":"0.45"},{"v":-1.16010940598681,"d":"-1.16"},{"v":0.0878062103875687,"d":"0.09"},{"v":0.816207877391866,"d":"0.82"},"down","no"]
["ENSG00000164144","ARFIP1","ENST00000356064;ENST00000509413;ENST00000405727;ENST00000513361;ENST00000353617;ENST00000511289;ENST00000514499;ENST00000510497;ENST00000451320","GO:0019904(protein domain specific binding);GO:0000139(Golgi membrane);GO:0045296(cadherin binding);GO:0070273(phosphatidylinositol-4-phosphate binding);GO:0050708(regulation of protein secretion);GO:0032588(trans-Golgi network membrane);GO:0005829(cytosol);GO:0034315(regulation of Arp2/3 complex-mediated actin nucleation);GO:0006886(intracellular protein transport);GO:0006886(intracellular protein transport)","NA","NA","NA","ADP ribosylation factor interacting protein 1 [Source:HGNC Symbol;Acc:HGNC:21496]",{"v":1.14287209323026,"d":"1.14"},{"v":2.57463527360038,"d":"2.57"},{"v":0.443896696727868,"d":"0.44"},{"v":-1.17170412204786,"d":"-1.17"},{"v":0.0878945264534442,"d":"0.09"},{"v":0.816207877391866,"d":"0.82"},"down","no"]
["MSTRG.228","TCEA3","ENST00000450454;ENST00000476978;ENST00000374602;ENST00000374601","GO:0005634(nucleus);GO:0003676(nucleic acid binding);GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0003677(DNA binding)","NA","NA","NA","transcription elongation factor A3 [Source:HGNC Symbol;Acc:HGNC:11615]",{"v":2.27871349274538,"d":"2.28"},{"v":1.0495939140825,"d":"1.05"},{"v":2.1710429740223,"d":"2.17"},{"v":1.11838828320559,"d":"1.12"},{"v":0.0879107803502118,"d":"0.09"},{"v":0.816207877391866,"d":"0.82"},"up","no"]
["ENSG00000114346","ECT2","ENST00000540509;ENST00000366090;ENST00000232458;ENST00000487073;ENST00000460860","GO:0005634(nucleus);GO:0006810(transport);GO:0005737(cytoplasm);GO:0015031(protein transport);GO:0005829(cytosol);GO:0035556(intracellular signal transduction);GO:0051301(cell division);GO:0042803(protein homodimerization activity);GO:0005089(Rho guanyl-nucleotide exchange factor activity);GO:0035023(regulation of Rho protein signal transduction);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0004871(signal transducer activity);GO:0005096(GTPase activator activity);GO:0007049(cell cycle);GO:0030054(cell junction);GO:0007399(nervous system development);GO:0030154(cell differentiation);GO:0000902(cell morphogenesis);GO:0005085(guanyl-nucleotide exchange factor activity);GO:0005819(spindle);GO:0030496(midbody);GO:0000910(cytokinesis);GO:0045666(positive regulation of neuron differentiation);GO:0005923(bicellular tight junction);GO:0051056(regulation of small GTPase mediated signal transduction);GO:0043547(positive regulation of GTPase activity);GO:0032154(cleavage furrow);GO:0090630(activation of GTPase activity);GO:0043065(positive regulation of apoptotic process);GO:0042307(positive regulation of protein import into nucleus);GO:0043123(positive regulation of I-kappaB kinase/NF-kappaB signaling);GO:0005911(cell-cell junction);GO:0032467(positive regulation of cytokinesis);GO:0045859(regulation of protein kinase activity);GO:0071479(cellular response to ionizing radiation);GO:0051260(protein homooligomerization);GO:0070830(bicellular tight junction assembly);GO:0071277(cellular response to calcium ion);GO:0072686(mitotic spindle);GO:0032147(activation of protein kinase activity);GO:0070301(cellular response to hydrogen peroxide);GO:0051988(regulation of attachment of spindle microtubules to kinetochore);GO:0097149(centralspindlin complex);GO:0017048(Rho GTPase binding);GO:0017048(Rho GTPase binding)","NA","NA","NA","epithelial cell transforming 2 [Source:HGNC Symbol;Acc:HGNC:3155]",{"v":0.285431858519731,"d":"0.29"},{"v":0.65574053718858,"d":"0.66"},{"v":0.435281704168375,"d":"0.44"},{"v":-1.19997871308057,"d":"-1.20"},{"v":0.0880033212402763,"d":"0.09"},{"v":0.816437591968727,"d":"0.82"},"down","no"]
["MSTRG.15415","NKRF","ENST00000304449;ENST00000371527;ENST00000542113","GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005730(nucleolus);GO:0006366(transcription from RNA polymerase II promoter);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0045892(negative regulation of transcription, DNA-templated);GO:0001077(transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0001077(transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding)","NA","NA","NA","NFKB repressing factor [Source:HGNC Symbol;Acc:HGNC:19374]",{"v":0.666687933816184,"d":"0.67"},{"v":1.51449276798202,"d":"1.51"},{"v":0.440205425810326,"d":"0.44"},{"v":-1.18375116741935,"d":"-1.18"},{"v":0.0881132991854726,"d":"0.09"},{"v":0.81663836724572,"d":"0.82"},"down","no"]
["MSTRG.3684","SELPLG","ENST00000550948;ENST00000228463;MSTRG.3684.1;ENST00000388962","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0007155(cell adhesion);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0050900(leukocyte migration);GO:0046718(viral entry into host cell);GO:0016032(viral process);GO:0005887(integral component of plasma membrane);GO:0005102(receptor binding);GO:0001931(uropod);GO:0001618(virus receptor activity);GO:0050901(leukocyte tethering or rolling);GO:0044853(plasma membrane raft);GO:0050902(leukocyte adhesive activation);GO:0071354(cellular response to interleukin-6);GO:0071354(cellular response to interleukin-6)","04514(Cell adhesion molecules (CAMs));05150(Staphylococcus aureus infection);05150(Staphylococcus aureus infection)","K06544","NA","selectin P ligand [Source:HGNC Symbol;Acc:HGNC:10722]",{"v":127.179153889913,"d":"127.18"},{"v":59.2835965649623,"d":"59.28"},{"v":2.14526717775214,"d":"2.15"},{"v":1.1011573363095,"d":"1.10"},{"v":0.0882855241742528,"d":"0.09"},{"v":0.81663836724572,"d":"0.82"},"up","no"]
["ENSG00000155329","ZCCHC10","ENST00000324170;ENST00000508080;ENST00000509008;ENST00000506403;ENST00000509437;ENST00000355372;ENST00000504170;ENST00000513541;ENST00000513848","GO:0003676(nucleic acid binding);GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0005515(protein binding);GO:0005515(protein binding)","NA","NA","NA","zinc finger CCHC-type containing 10 [Source:HGNC Symbol;Acc:HGNC:25954]",{"v":1.19682650644783,"d":"1.20"},{"v":2.71938277842907,"d":"2.72"},{"v":0.440109614557172,"d":"0.44"},{"v":-1.18406520594872,"d":"-1.18"},{"v":0.0883260506898497,"d":"0.09"},{"v":0.81663836724572,"d":"0.82"},"down","no"]
["MSTRG.2368","AC090559.1","ENST00000527426;ENST00000532340;ENST00000532943","NA","NA","NA","NA",null,{"v":1.59806932255166,"d":"1.60"},{"v":3.66164591105121,"d":"3.66"},{"v":0.436434696683404,"d":"0.44"},{"v":-1.19616229399746,"d":"-1.20"},{"v":0.0884196658645151,"d":"0.09"},{"v":0.81663836724572,"d":"0.82"},"down","no"]
["MSTRG.4350","REC8","ENST00000560032;ENST00000558191;ENST00000619284;ENST00000559797;ENST00000560823;ENST00000611366;ENST00000558381;ENST00000619469;ENST00000560501;ENST00000620473;ENST00000619111","GO:0005634(nucleus);GO:0005694(chromosome);GO:0051321(meiotic cell cycle);GO:0000228(nuclear chromosome);GO:0003682(chromatin binding);GO:0007059(chromosome segregation);GO:0000775(chromosome, centromeric region);GO:0006302(double-strand break repair);GO:0007283(spermatogenesis);GO:0007131(reciprocal meiotic recombination);GO:0000798(nuclear cohesin complex);GO:0000724(double-strand break repair via homologous recombination);GO:0001556(oocyte maturation);GO:0007062(sister chromatid cohesion);GO:0007129(synapsis);GO:0007130(synaptonemal complex assembly);GO:0007141(male meiosis I);GO:0007286(spermatid development);GO:0009566(fertilization);GO:0072520(seminiferous tubule development);GO:0000778(condensed nuclear chromosome kinetochore);GO:0000780(condensed nuclear chromosome, centromeric region);GO:0000793(condensed chromosome);GO:0000794(condensed nuclear chromosome);GO:0000795(synaptonemal complex);GO:0000800(lateral element);GO:0001673(male germ cell nucleus);GO:0030893(meiotic cohesin complex);GO:0034991(nuclear meiotic cohesin complex);GO:0034991(nuclear meiotic cohesin complex)","04114(Oocyte meiosis);04114(Oocyte meiosis)","K13054","NA","REC8 meiotic recombination protein [Source:HGNC Symbol;Acc:HGNC:16879]",{"v":1.92350821331946,"d":"1.92"},{"v":0.882576758584807,"d":"0.88"},{"v":2.17942314321053,"d":"2.18"},{"v":1.12394632832412,"d":"1.12"},{"v":0.0884785227163031,"d":"0.09"},{"v":0.81663836724572,"d":"0.82"},"up","no"]
["ENSG00000132953","XPO4","ENST00000255305;ENST00000490513;ENST00000465018","GO:0006810(transport);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0015031(protein transport);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0005515(protein binding);GO:0005643(nuclear pore);GO:0005049(nuclear export signal receptor activity);GO:0008536(Ran GTPase binding);GO:0046827(positive regulation of protein export from nucleus);GO:0006611(protein export from nucleus);GO:0006611(protein export from nucleus)","NA","NA","NA","exportin 4 [Source:HGNC Symbol;Acc:HGNC:17796]",{"v":1.21170038952381,"d":"1.21"},{"v":0.561296353428571,"d":"0.56"},{"v":2.15875336107632,"d":"2.16"},{"v":1.11019842396352,"d":"1.11"},{"v":0.0884988305922621,"d":"0.09"},{"v":0.81663836724572,"d":"0.82"},"up","no"]
["MSTRG.2965","ETS1","ENST00000526145;ENST00000535549;ENST00000319397;ENST00000392668;ENST00000530924;ENST00000608978;ENST00000531611","GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0005634(nucleus);GO:0050729(positive regulation of inflammatory response);GO:1904996(positive regulation of leukocyte adhesion to vascular endothelial cell);GO:0005737(cytoplasm);GO:0005654(nucleoplasm);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0043565(sequence-specific DNA binding);GO:0005515(protein binding);GO:0002376(immune system process);GO:0042802(identical protein binding);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:0006955(immune response);GO:0008134(transcription factor binding);GO:0045893(positive regulation of transcription, DNA-templated);GO:0000982(transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0001077(transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0008285(negative regulation of cell proliferation);GO:0010595(positive regulation of endothelial cell migration);GO:0045765(regulation of angiogenesis);GO:0048870(cell motility);GO:0035035(histone acetyltransferase binding);GO:1990837(sequence-specific double-stranded DNA binding);GO:0001666(response to hypoxia);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0007565(female pregnancy);GO:0008284(positive regulation of cell proliferation);GO:0009611(response to wounding);GO:0009612(response to mechanical stimulus);GO:0010715(regulation of extracellular matrix disassembly);GO:0021854(hypothalamus development);GO:0021983(pituitary gland development);GO:0030335(positive regulation of cell migration);GO:0030578(PML body organization);GO:0032355(response to estradiol);GO:0034616(response to laminar fluid shear stress);GO:0044849(estrous cycle);GO:0045648(positive regulation of erythrocyte differentiation);GO:0045766(positive regulation of angiogenesis);GO:0050728(negative regulation of inflammatory response);GO:0051272(positive regulation of cellular component movement);GO:0060055(angiogenesis involved in wound healing);GO:0061614(pri-miRNA transcription from RNA polymerase II promoter);GO:0070301(cellular response to hydrogen peroxide);GO:0070555(response to interleukin-1);GO:0005667(transcription factor complex);GO:0005667(transcription factor complex)","04014(Ras signaling pathway);04218(Cellular senescence);05200(Pathways in cancer);05211(Renal cell carcinoma);05166(HTLV-I infection);05166(HTLV-I infection)","K02678","NA","ETS proto-oncogene 1, transcription factor [Source:HGNC Symbol;Acc:HGNC:3488]",{"v":30.2950078100434,"d":"30.30"},{"v":14.1273097259757,"d":"14.13"},{"v":2.14442865610431,"d":"2.14"},{"v":1.10059331914593,"d":"1.10"},{"v":0.0885484188222806,"d":"0.09"},{"v":0.81663836724572,"d":"0.82"},"up","no"]
["MSTRG.6790","ERBB2","ENST00000584601;ENST00000583038;ENST00000584014;ENST00000269571;ENST00000584908;ENST00000578630;ENST00000584099;ENST00000584684;ENST00000578373;ENST00000583391;ENST00000406381;ENST00000578502","GO:0001934(positive regulation of protein phosphorylation);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0005829(cytosol);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0004713(protein tyrosine kinase activity);GO:0007169(transmembrane receptor protein tyrosine kinase signaling pathway);GO:0018108(peptidyl-tyrosine phosphorylation);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0007165(signal transduction);GO:0004714(transmembrane receptor protein tyrosine kinase activity);GO:0048471(perinuclear region of cytoplasm);GO:0045727(positive regulation of translation);GO:0004716(signal transducer, downstream of receptor, with protein tyrosine kinase activity);GO:0046854(phosphatidylinositol phosphorylation);GO:0042802(identical protein binding);GO:0000165(MAPK cascade);GO:0090314(positive regulation of protein targeting to membrane);GO:0010008(endosome membrane);GO:0008022(protein C-terminus binding);GO:0046982(protein heterodimerization activity);GO:0043547(positive regulation of GTPase activity);GO:0019903(protein phosphatase binding);GO:0046934(phosphatidylinositol-4,5-bisphosphate 3-kinase activity);GO:0014066(regulation of phosphatidylinositol 3-kinase signaling);GO:0038111(interleukin-7-mediated signaling pathway);GO:0048015(phosphatidylinositol-mediated signaling);GO:0005088(Ras guanyl-nucleotide exchange factor activity);GO:0008283(cell proliferation);GO:0030307(positive regulation of cell growth);GO:0038128(ERBB2 signaling pathway);GO:1901185(negative regulation of ERBB signaling pathway);GO:2000145(regulation of cell motility);GO:0019838(growth factor binding);GO:0043235(receptor complex);GO:0050679(positive regulation of epithelial cell proliferation);GO:0071363(cellular response to growth factor stimulus);GO:0046983(protein dimerization activity);GO:0032886(regulation of microtubule-based process);GO:0071364(cellular response to epidermal growth factor stimulus);GO:0043406(positive regulation of MAP kinase activity);GO:0070372(regulation of ERK1 and ERK2 cascade);GO:0045765(regulation of angiogenesis);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0007166(cell surface receptor signaling pathway);GO:0016323(basolateral plasma membrane);GO:0042060(wound healing);GO:0007167(enzyme linked receptor protein signaling pathway);GO:0001042(RNA polymerase I core binding);GO:0004888(transmembrane signaling receptor activity);GO:0043125(ErbB-3 class receptor binding);GO:0014065(phosphatidylinositol 3-kinase signaling);GO:0045785(positive regulation of cell adhesion);GO:0045943(positive regulation of transcription from RNA polymerase I promoter);GO:0045945(positive regulation of transcription from RNA polymerase III promoter);GO:0046777(protein autophosphorylation);GO:0005622(intracellular);GO:0023014(signal transduction by protein phosphorylation);GO:0035556(intracellular signal transduction);GO:0007399(nervous system development);GO:0007422(peripheral nervous system development);GO:0007507(heart development);GO:0007528(neuromuscular junction development);GO:0008045(motor neuron axon guidance);GO:0010628(positive regulation of gene expression);GO:0033088(negative regulation of immature T cell proliferation in thymus);GO:0042552(myelination);GO:0048709(oligodendrocyte differentiation);GO:0016324(apical plasma membrane);GO:0031410(cytoplasmic vesicle);GO:0043209(myelin sheath);GO:0043209(myelin sheath)","04012(ErbB signaling pathway);04066(HIF-1 signaling pathway);04020(Calcium signaling pathway);04510(Focal adhesion);04520(Adherens junction);04530(Tight junction);05200(Pathways in cancer);05230(Central carbon metabolism in cancer);05206(MicroRNAs in cancer);05205(Proteoglycans in cancer);05212(Pancreatic cancer);05226(Gastric cancer);05219(Bladder cancer);05215(Prostate cancer);05213(Endometrial cancer);05224(Breast cancer);05223(Non-small cell lung cancer);01521(EGFR tyrosine kinase inhibitor resistance);01524(Platinum drug resistance);01522(Endocrine resistance);01522(Endocrine resistance)","K05083","EC:2.7.10.1","erb-b2 receptor tyrosine kinase 2 [Source:HGNC Symbol;Acc:HGNC:3430]",{"v":1.1241789799438,"d":"1.12"},{"v":0.518310617769596,"d":"0.52"},{"v":2.16892909657415,"d":"2.17"},{"v":1.11698289132608,"d":"1.12"},{"v":0.0886220592087989,"d":"0.09"},{"v":0.81663836724572,"d":"0.82"},"up","no"]
["MSTRG.6797","RARA-AS1","ENST00000581080","NA","NA","NA","NA","RARA antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:49577]",{"v":1.306205,"d":"1.31"},{"v":2.955265,"d":"2.96"},{"v":0.44199251166985,"d":"0.44"},{"v":-1.1779061675066,"d":"-1.18"},{"v":0.0886749334513251,"d":"0.09"},{"v":0.81663836724572,"d":"0.82"},"down","no"]
["MSTRG.8106","RASGRP4","ENST00000587738;ENST00000454404;ENST00000589100;ENST00000615439;ENST00000588708;ENST00000588404;ENST00000586305;ENST00000617966;ENST00000293062;ENST00000592322;ENST00000587753;ENST00000618320;ENST00000622174;ENST00000615340;ENST00000426920;ENST00000587287;ENST00000614135;ENST00000589474;ENST00000589358;ENST00000433821","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0007264(small GTPase mediated signal transduction);GO:0046872(metal ion binding);GO:0035556(intracellular signal transduction);GO:0005509(calcium ion binding);GO:0005886(plasma membrane);GO:0043547(positive regulation of GTPase activity);GO:0030154(cell differentiation);GO:0005085(guanyl-nucleotide exchange factor activity);GO:0005829(cytosol);GO:0000165(MAPK cascade);GO:0008283(cell proliferation);GO:0005088(Ras guanyl-nucleotide exchange factor activity);GO:0007169(transmembrane receptor protein tyrosine kinase signaling pathway);GO:0030742(GTP-dependent protein binding);GO:0016049(cell growth);GO:0046579(positive regulation of Ras protein signal transduction);GO:0008277(regulation of G-protein coupled receptor protein signaling pathway);GO:0019992(diacylglycerol binding);GO:0007202(activation of phospholipase C activity);GO:0030099(myeloid cell differentiation);GO:0009991(response to extracellular stimulus);GO:0005622(intracellular);GO:0005622(intracellular)","04014(Ras signaling pathway);04010(MAPK signaling pathway);05200(Pathways in cancer);05200(Pathways in cancer)","K12363","NA","RAS guanyl releasing protein 4 [Source:HGNC Symbol;Acc:HGNC:18958]",{"v":15.1864219132202,"d":"15.19"},{"v":33.7818448204638,"d":"33.78"},{"v":0.449543889445044,"d":"0.45"},{"v":-1.15346612042983,"d":"-1.15"},{"v":0.0887180196513064,"d":"0.09"},{"v":0.81663836724572,"d":"0.82"},"down","no"]
["MSTRG.7859","PRDX2","ENST00000301522;ENST00000477555;ENST00000498785;ENST00000478908;ENST00000334482;ENST00000466174","GO:0005623(cell);GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0045454(cell redox homeostasis);GO:0016209(antioxidant activity);GO:0008379(thioredoxin peroxidase activity);GO:0019430(removal of superoxide radicals);GO:0005737(cytoplasm);GO:0004601(peroxidase activity);GO:0051920(peroxiredoxin activity);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0042981(regulation of apoptotic process);GO:0043066(negative regulation of apoptotic process);GO:0006979(response to oxidative stress);GO:0034599(cellular response to oxidative stress);GO:0042744(hydrogen peroxide catabolic process);GO:0042744(hydrogen peroxide catabolic process)","NA","NA","NA","peroxiredoxin 2 [Source:HGNC Symbol;Acc:HGNC:9353]",{"v":15.49484329957,"d":"15.49"},{"v":7.20412821356904,"d":"7.20"},{"v":2.15082836399071,"d":"2.15"},{"v":1.10489240235319,"d":"1.10"},{"v":0.0887709369477369,"d":"0.09"},{"v":0.81663836724572,"d":"0.82"},"up","no"]
["ENSG00000187522","HSPA14","ENST00000378372;ENST00000493178;ENST00000470430;ENST00000437161;ENST00000441647","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0005840(ribosome);GO:0005829(cytosol);GO:0005515(protein binding);GO:0051083('de novo' cotranslational protein folding);GO:0051083('de novo' cotranslational protein folding)","NA","NA","NA","heat shock protein family A (Hsp70) member 14 [Source:HGNC Symbol;Acc:HGNC:29526]",{"v":0.543731532540238,"d":"0.54"},{"v":1.2336701616515,"d":"1.23"},{"v":0.440743036057832,"d":"0.44"},{"v":-1.18199032040533,"d":"-1.18"},{"v":0.0888407328870096,"d":"0.09"},{"v":0.816656569026999,"d":"0.82"},"down","no"]
["MSTRG.14377","YTHDF3","ENST00000539294;ENST00000617200;ENST00000621957;ENST00000623280;ENST00000612880;ENST00000518373;ENST00000621413;ENST00000522282;ENST00000617952;ENST00000621820;ENST00000621890;ENST00000519428","GO:0003723(RNA binding);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005515(protein binding);GO:0043022(ribosome binding);GO:0045727(positive regulation of translation);GO:0045948(positive regulation of translational initiation);GO:1990247(N6-methyladenosine-containing RNA binding);GO:0061157(mRNA destabilization);GO:0061157(mRNA destabilization)","NA","NA","NA","YTH N6-methyladenosine RNA binding protein 3 [Source:HGNC Symbol;Acc:HGNC:26465]",{"v":3.96730954746065,"d":"3.97"},{"v":8.82971360782087,"d":"8.83"},{"v":0.449313502529304,"d":"0.45"},{"v":-1.15420567727404,"d":"-1.15"},{"v":0.0889727546120169,"d":"0.09"},{"v":0.8172463089534,"d":"0.82"},"down","no"]
["MSTRG.1467","AL445524.1","ENST00000425412;ENST00000454631;ENST00000416221","NA","NA","NA","NA",null,{"v":0.608668643486778,"d":"0.61"},{"v":1.47393292360431,"d":"1.47"},{"v":0.412955456614917,"d":"0.41"},{"v":-1.27594192095807,"d":"-1.28"},{"v":0.0892298939702324,"d":"0.09"},{"v":0.818232532736702,"d":"0.82"},"down","no"]
["ENSG00000268205","AC005261.2","ENST00000593427","NA","NA","NA","NA",null,{"v":0.7256,"d":"0.73"},{"v":0.328732,"d":"0.33"},{"v":2.20726914325347,"d":"2.21"},{"v":1.14226255529172,"d":"1.14"},{"v":0.0892596497896246,"d":"0.09"},{"v":0.818232532736702,"d":"0.82"},"up","no"]
["MSTRG.5627","UBN1","ENST00000262376;ENST00000396658;ENST00000590769;ENST00000586716;ENST00000586152;ENST00000587027;ENST00000592120;ENST00000585857","GO:0005634(nucleus);GO:0006325(chromatin organization);GO:0005654(nucleoplasm);GO:0016569(covalent chromatin modification);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0016604(nuclear body);GO:0030054(cell junction);GO:0005923(bicellular tight junction);GO:0016032(viral process);GO:0010923(negative regulation of phosphatase activity);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0016605(PML body);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0006336(DNA replication-independent nucleosome assembly);GO:0006336(DNA replication-independent nucleosome assembly)","NA","NA","NA","ubinuclein 1 [Source:HGNC Symbol;Acc:HGNC:12506]",{"v":6.63775216278798,"d":"6.64"},{"v":14.7357970570693,"d":"14.74"},{"v":0.450450840024538,"d":"0.45"},{"v":-1.15055842885466,"d":"-1.15"},{"v":0.0893149110607464,"d":"0.09"},{"v":0.818232532736702,"d":"0.82"},"down","no"]
["MSTRG.14863","TSTD2","ENST00000341170;ENST00000375172;ENST00000375165;ENST00000375163;ENST00000375173;ENST00000484708","GO:0005515(protein binding);GO:0003674(molecular_function);GO:0008150(biological_process);GO:0005575(cellular_component);GO:0005575(cellular_component)","NA","NA","NA","thiosulfate sulfurtransferase like domain containing 2 [Source:HGNC Symbol;Acc:HGNC:30087]",{"v":0.685802189617021,"d":"0.69"},{"v":1.54809086229787,"d":"1.55"},{"v":0.44299866779077,"d":"0.44"},{"v":-1.17462573465005,"d":"-1.17"},{"v":0.0893519166707161,"d":"0.09"},{"v":0.818232532736702,"d":"0.82"},"down","no"]
["MSTRG.13618","UBE2D4","ENST00000222402;ENST00000450743;ENST00000446008;ENST00000454350;ENST00000440899;ENST00000415051;ENST00000443780;ENST00000491770;ENST00000440652","GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0016740(transferase activity);GO:0016567(protein ubiquitination);GO:0005515(protein binding);GO:0061631(ubiquitin conjugating enzyme activity);GO:0004842(ubiquitin-protein transferase activity);GO:0070534(protein K63-linked ubiquitination);GO:0070936(protein K48-linked ubiquitination);GO:0070979(protein K11-linked ubiquitination);GO:0085020(protein K6-linked ubiquitination);GO:0035519(protein K29-linked ubiquitination);GO:0044314(protein K27-linked ubiquitination);GO:0044314(protein K27-linked ubiquitination)","04141(Protein processing in endoplasmic reticulum);04120(Ubiquitin mediated proteolysis);04120(Ubiquitin mediated proteolysis)","K06689","EC:2.3.2.23","ubiquitin conjugating enzyme E2 D4 (putative) [Source:HGNC Symbol;Acc:HGNC:21647]",{"v":1.02042116359007,"d":"1.02"},{"v":0.461932139189476,"d":"0.46"},{"v":2.20902829013054,"d":"2.21"},{"v":1.14341189482252,"d":"1.14"},{"v":0.0894636878993299,"d":"0.09"},{"v":0.818633533194325,"d":"0.82"},"up","no"]
["MSTRG.4087","RPS26P47","ENST00000427219","NA","NA","NA","NA","ribosomal protein S26 pseudogene 47 [Source:HGNC Symbol;Acc:HGNC:36368]",{"v":51.703289,"d":"51.70"},{"v":24.084984,"d":"24.08"},{"v":2.14670223571666,"d":"2.15"},{"v":1.10212209205984,"d":"1.10"},{"v":0.0896160366826385,"d":"0.09"},{"v":0.818867035118176,"d":"0.82"},"up","no"]
["ENSG00000157404","KIT","ENST00000514582;ENST00000288135;ENST00000412167","GO:0005615(extracellular space);GO:1905065(positive regulation of vascular smooth muscle cell differentiation);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0004713(protein tyrosine kinase activity);GO:0007169(transmembrane receptor protein tyrosine kinase signaling pathway);GO:0005886(plasma membrane);GO:0042803(protein homodimerization activity);GO:0043547(positive regulation of GTPase activity);GO:0005515(protein binding);GO:0004714(transmembrane receptor protein tyrosine kinase activity);GO:0030218(erythrocyte differentiation);GO:0007283(spermatogenesis);GO:0004716(signal transducer, downstream of receptor, with protein tyrosine kinase activity);GO:0019955(cytokine binding);GO:0038093(Fc receptor signaling pathway);GO:0038109(Kit signaling pathway);GO:0006954(inflammatory response);GO:0046854(phosphatidylinositol phosphorylation);GO:0042629(mast cell granule);GO:0000165(MAPK cascade);GO:0008584(male gonad development);GO:0048863(stem cell differentiation);GO:0008360(regulation of cell shape);GO:0042127(regulation of cell proliferation);GO:0007165(signal transduction);GO:0030032(lamellipodium assembly);GO:0046934(phosphatidylinositol-4,5-bisphosphate 3-kinase activity);GO:0002551(mast cell chemotaxis);GO:0014066(regulation of phosphatidylinositol 3-kinase signaling);GO:0030217(T cell differentiation);GO:0038111(interleukin-7-mediated signaling pathway);GO:0043303(mast cell degranulation);GO:0048015(phosphatidylinositol-mediated signaling);GO:0060374(mast cell differentiation);GO:0046777(protein autophosphorylation);GO:0005088(Ras guanyl-nucleotide exchange factor activity);GO:0030097(hemopoiesis);GO:0060326(cell chemotaxis);GO:0051091(positive regulation of sequence-specific DNA binding transcription factor activity);GO:0019221(cytokine-mediated signaling pathway);GO:0000187(activation of MAPK activity);GO:0031532(actin cytoskeleton reorganization);GO:0043410(positive regulation of MAPK cascade);GO:0014068(positive regulation of phosphatidylinositol 3-kinase signaling);GO:0019827(stem cell population maintenance);GO:0042531(positive regulation of tyrosine phosphorylation of STAT protein);GO:0030318(melanocyte differentiation);GO:0035855(megakaryocyte development);GO:0001541(ovarian follicle development);GO:0018108(peptidyl-tyrosine phosphorylation);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0043552(positive regulation of phosphatidylinositol 3-kinase activity);GO:0038162(erythropoietin-mediated signaling pathway);GO:0010863(positive regulation of phospholipase C activity);GO:0050910(detection of mechanical stimulus involved in sensory perception of sound);GO:0032762(mast cell cytokine production);GO:0002327(immature B cell differentiation);GO:0002371(dendritic cell cytokine production);GO:0035162(embryonic hemopoiesis);GO:0043473(pigmentation);GO:0046427(positive regulation of JAK-STAT cascade);GO:0048565(digestive tract development);GO:0070662(mast cell proliferation);GO:0097324(melanocyte migration);GO:0097326(melanocyte adhesion);GO:0023014(signal transduction by protein phosphorylation);GO:0002020(protease binding);GO:0005020(stem cell factor receptor activity);GO:0002318(myeloid progenitor cell differentiation);GO:0002320(lymphoid progenitor cell differentiation);GO:0002573(myeloid leukocyte differentiation);GO:0006687(glycosphingolipid metabolic process);GO:0007286(spermatid development);GO:0008284(positive regulation of cell proliferation);GO:0008354(germ cell migration);GO:0008542(visual learning);GO:0009314(response to radiation);GO:0010628(positive regulation of gene expression);GO:0030335(positive regulation of cell migration);GO:0031274(positive regulation of pseudopodium assembly);GO:0035019(somatic stem cell population maintenance);GO:0035234(ectopic germ cell programmed cell death);GO:0035556(intracellular signal transduction);GO:0035701(hematopoietic stem cell migration);GO:0043069(negative regulation of programmed cell death);GO:0043406(positive regulation of MAP kinase activity);GO:0043586(tongue development);GO:0045747(positive regulation of Notch signaling pathway);GO:0046686(response to cadmium ion);GO:0048066(developmental pigmentation);GO:0048070(regulation of developmental pigmentation);GO:0048103(somatic stem cell division);GO:0048170(positive regulation of long-term neuronal synaptic plasticity);GO:0050673(epithelial cell proliferation);GO:0097067(cellular response to thyroid hormone stimulus);GO:0120072(-);GO:1904251(regulation of bile acid metabolic process);GO:1904343(positive regulation of colon smooth muscle contraction);GO:1904349(positive regulation of small intestine smooth muscle contraction);GO:0001669(acrosomal vesicle);GO:0005911(cell-cell junction);GO:0009897(external side of plasma membrane);GO:0009898(cytoplasmic side of plasma membrane);GO:0009986(cell surface);GO:0009986(cell surface)","04014(Ras signaling pathway);04015(Rap1 signaling pathway);04010(MAPK signaling pathway);04072(Phospholipase D signaling pathway);04151(PI3K-Akt signaling pathway);04060(Cytokine-cytokine receptor interaction);04640(Hematopoietic cell lineage);04916(Melanogenesis);05200(Pathways in cancer);05230(Central carbon metabolism in cancer);05221(Acute myeloid leukemia);05224(Breast cancer);05224(Breast cancer)","K05091","EC:2.7.10.1","KIT proto-oncogene receptor tyrosine kinase [Source:HGNC Symbol;Acc:HGNC:6342]",{"v":0.210599127449218,"d":"0.21"},{"v":0.493332935825993,"d":"0.49"},{"v":0.426890467178336,"d":"0.43"},{"v":-1.22806214853066,"d":"-1.23"},{"v":0.0897881324097579,"d":"0.09"},{"v":0.818867035118176,"d":"0.82"},"down","no"]
["MSTRG.7895","ASF1B","ENST00000263382;ENST00000590835;ENST00000589468;ENST00000474890","GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0016569(covalent chromatin modification);GO:0000790(nuclear chromatin);GO:0007275(multicellular organism development);GO:0030154(cell differentiation);GO:0042393(histone binding);GO:0006333(chromatin assembly or disassembly);GO:0006334(nucleosome assembly);GO:0000785(chromatin);GO:0007283(spermatogenesis);GO:0005515(protein binding);GO:0043234(protein complex);GO:0006335(DNA replication-dependent nucleosome assembly);GO:0006336(DNA replication-independent nucleosome assembly);GO:0006336(DNA replication-independent nucleosome assembly)","NA","NA","NA","anti-silencing function 1B histone chaperone [Source:HGNC Symbol;Acc:HGNC:20996]",{"v":2.40848194010417,"d":"2.41"},{"v":5.37381549435764,"d":"5.37"},{"v":0.448188431968498,"d":"0.45"},{"v":-1.15782268244481,"d":"-1.16"},{"v":0.0898071849028226,"d":"0.09"},{"v":0.818867035118176,"d":"0.82"},"down","no"]
["MSTRG.9620","THBD","ENST00000377103","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005509(calcium ion binding);GO:0005887(integral component of plasma membrane);GO:0005515(protein binding);GO:0004888(transmembrane signaling receptor activity);GO:0007165(signal transduction);GO:0050900(leukocyte migration);GO:0005886(plasma membrane);GO:0030195(negative regulation of blood coagulation);GO:0009986(cell surface);GO:0004872(receptor activity);GO:0007596(blood coagulation);GO:0007599(hemostasis);GO:0010544(negative regulation of platelet activation);GO:0051918(negative regulation of fibrinolysis);GO:0007565(female pregnancy);GO:0010165(response to X-ray);GO:0032496(response to lipopolysaccharide);GO:0051591(response to cAMP);GO:0005615(extracellular space);GO:0005774(vacuolar membrane);GO:0016327(apicolateral plasma membrane)","04610(Complement and coagulation cascades);05418(Fluid shear stress and atherosclerosis);04933(AGE-RAGE signaling pathway in diabetic complications)","K03907","NA","thrombomodulin [Source:HGNC Symbol;Acc:HGNC:11784]",{"v":3.246247,"d":"3.25"},{"v":7.221391,"d":"7.22"},{"v":0.44953209153195,"d":"0.45"},{"v":-1.15350398328252,"d":"-1.15"},{"v":0.0898376984994544,"d":"0.09"},{"v":0.818867035118176,"d":"0.82"},"down","no"]
["ENSG00000198382","UVRAG","ENST00000356136;ENST00000531818;ENST00000533454;ENST00000530501;ENST00000525183","GO:0005694(chromosome);GO:0005783(endoplasmic reticulum);GO:0005515(protein binding);GO:0006281(DNA repair);GO:0006974(cellular response to DNA damage stimulus);GO:0005764(lysosome);GO:0005813(centrosome);GO:0030496(midbody);GO:0000775(chromosome, centromeric region);GO:0005768(endosome);GO:0005769(early endosome);GO:0005770(late endosome);GO:0007098(centrosome cycle);GO:0000149(SNARE binding);GO:0010508(positive regulation of autophagy);GO:0005737(cytoplasm);GO:0032465(regulation of cytokinesis);GO:0006914(autophagy);GO:0032801(receptor catabolic process);GO:0071985(multivesicular body sorting pathway);GO:1901098(positive regulation of autophagosome maturation);GO:0030897(HOPS complex);GO:0070418(DNA-dependent protein kinase complex);GO:0017124(SH3 domain binding);GO:0006890(retrograde vesicle-mediated transport, Golgi to ER);GO:0007051(spindle organization);GO:0007059(chromosome segregation);GO:0035493(SNARE complex assembly);GO:0046718(viral entry into host cell);GO:0051684(maintenance of Golgi location);GO:0060627(regulation of vesicle-mediated transport);GO:0071900(regulation of protein serine/threonine kinase activity);GO:0097680(double-strand break repair via classical nonhomologous end joining);GO:0043234(protein complex);GO:0045335(phagocytic vesicle);GO:0045335(phagocytic vesicle)","04140(Autophagy - animal);04140(Autophagy - animal)","K21249","NA","UV radiation resistance associated [Source:HGNC Symbol;Acc:HGNC:12640]",{"v":0.926792180887909,"d":"0.93"},{"v":2.07071297906171,"d":"2.07"},{"v":0.447571532249661,"d":"0.45"},{"v":-1.15980981815382,"d":"-1.16"},{"v":0.0898478800226128,"d":"0.09"},{"v":0.818867035118176,"d":"0.82"},"down","no"]
["ENSG00000111110","PPM1H","ENST00000228705;ENST00000551519","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005654(nucleoplasm);GO:0016787(hydrolase activity);GO:0003824(catalytic activity);GO:0006470(protein dephosphorylation);GO:0004721(phosphoprotein phosphatase activity);GO:0004722(protein serine/threonine phosphatase activity);GO:0004722(protein serine/threonine phosphatase activity)","NA","NA","NA","protein phosphatase, Mg2+/Mn2+ dependent 1H [Source:HGNC Symbol;Acc:HGNC:18583]",{"v":0.362330118504885,"d":"0.36"},{"v":0.817650798527538,"d":"0.82"},{"v":0.443135528219853,"d":"0.44"},{"v":-1.17418009590867,"d":"-1.17"},{"v":0.089906475432081,"d":"0.09"},{"v":0.818867035118176,"d":"0.82"},"down","no"]
["MSTRG.160","DRAXIN","ENST00000294485","GO:0005576(extracellular region);GO:0005515(protein binding);GO:0007411(axon guidance);GO:0007275(multicellular organism development);GO:0016055(Wnt signaling pathway);GO:0090090(negative regulation of canonical Wnt signaling pathway);GO:0030900(forebrain development);GO:0021516(dorsal spinal cord development);GO:0021528(commissural neuron differentiation in spinal cord);GO:0030517(negative regulation of axon extension);GO:0043524(negative regulation of neuron apoptotic process)","NA","NA","NA","dorsal inhibitory axon guidance protein [Source:HGNC Symbol;Acc:HGNC:25054]",{"v":0.732121,"d":"0.73"},{"v":0.337686,"d":"0.34"},{"v":2.16805256954686,"d":"2.17"},{"v":1.11639973865906,"d":"1.12"},{"v":0.0899652123784543,"d":"0.09"},{"v":0.818867035118176,"d":"0.82"},"up","no"]
["ENSG00000021574","SPAST","ENST00000315285;ENST00000621856;ENST00000345662;ENST00000615843","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0016787(hydrolase activity);GO:0051301(cell division);GO:1904115(axon cytoplasm);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005856(cytoskeleton);GO:0003824(catalytic activity);GO:0008152(metabolic process);GO:0007049(cell cycle);GO:0007275(multicellular organism development);GO:0048471(perinuclear region of cytoplasm);GO:0007399(nervous system development);GO:0030154(cell differentiation);GO:0005874(microtubule);GO:0008017(microtubule binding);GO:0008568(microtubule-severing ATPase activity);GO:0051013(microtubule severing);GO:0005813(centrosome);GO:0005815(microtubule organizing center);GO:0005819(spindle);GO:0030496(midbody);GO:0005515(protein binding);GO:0005768(endosome);GO:0007409(axonogenesis);GO:0015630(microtubule cytoskeleton);GO:0070062(extracellular exosome);GO:0043014(alpha-tubulin binding);GO:0006888(ER to Golgi vesicle-mediated transport);GO:0031117(positive regulation of microtubule depolymerization);GO:0032506(cytokinetic process);GO:0034214(protein hexamerization);GO:0031965(nuclear membrane);GO:0008089(anterograde axonal transport);GO:0005811(lipid particle);GO:0010458(exit from mitosis);GO:0000281(mitotic cytokinesis);GO:0032467(positive regulation of cytokinesis);GO:0031410(cytoplasmic vesicle);GO:0048487(beta-tubulin binding);GO:0051260(protein homooligomerization);GO:0031468(nuclear envelope reassembly);GO:0001578(microtubule bundle formation);GO:0019896(axonal transport of mitochondrion);GO:0000815(ESCRT III complex);GO:0090148(membrane fission);GO:0006998(nuclear envelope organization);GO:0051228(mitotic spindle disassembly);GO:0051230(spindle disassembly);GO:0061640(cytoskeleton-dependent cytokinesis);GO:0061640(cytoskeleton-dependent cytokinesis)","NA","NA","NA","spastin [Source:HGNC Symbol;Acc:HGNC:11233]",{"v":1.32449804661423,"d":"1.32"},{"v":2.95139336658354,"d":"2.95"},{"v":0.448770422001536,"d":"0.45"},{"v":-1.15595050235845,"d":"-1.16"},{"v":0.0900968920265522,"d":"0.09"},{"v":0.819446203764155,"d":"0.82"},"down","no"]
["MSTRG.12217","FAM174A","ENST00000312637;ENST00000505792","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016021(integral component of membrane)","NA","NA","NA","family with sequence similarity 174 member A [Source:HGNC Symbol;Acc:HGNC:24943]",{"v":6.15929021186441,"d":"6.16"},{"v":13.6941318728814,"d":"13.69"},{"v":0.449775879846878,"d":"0.45"},{"v":-1.15272179917478,"d":"-1.15"},{"v":0.0901895004558878,"d":"0.09"},{"v":0.819651875293549,"d":"0.82"},"down","no"]
["MSTRG.15457","RAP2C","ENST00000342983;ENST00000370874;ENST00000460462;ENST00000620646;MSTRG.15457.4","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005525(GTP binding);GO:0000166(nucleotide binding);GO:0007165(signal transduction);GO:0003924(GTPase activity);GO:0005886(plasma membrane);GO:1903506(regulation of nucleic acid-templated transcription);GO:0003713(transcription coactivator activity);GO:0005923(bicellular tight junction);GO:0005768(endosome);GO:0070062(extracellular exosome);GO:0055038(recycling endosome membrane);GO:0043312(neutrophil degranulation);GO:0070821(tertiary granule membrane);GO:0019003(GDP binding);GO:0030336(negative regulation of cell migration);GO:0031954(positive regulation of protein autophosphorylation);GO:0044291(cell-cell contact zone);GO:0032486(Rap protein signal transduction);GO:0090557(establishment of endothelial intestinal barrier);GO:0061097(regulation of protein tyrosine kinase activity);GO:0005829(cytosol);GO:0055037(recycling endosome);GO:0055037(recycling endosome)","04530(Tight junction);04530(Tight junction)","K07839","NA","RAP2C, member of RAS oncogene family [Source:HGNC Symbol;Acc:HGNC:21165]",{"v":2.59224615541525,"d":"2.59"},{"v":5.76466647790189,"d":"5.76"},{"v":0.449678427252,"d":"0.45"},{"v":-1.1530344206716,"d":"-1.15"},{"v":0.0903040629408262,"d":"0.09"},{"v":0.819651875293549,"d":"0.82"},"down","no"]
["ENSG00000035664","DAPK2","ENST00000559007;ENST00000261891;ENST00000558076;ENST00000558064;ENST00000558482;ENST00000557867;ENST00000612884;ENST00000457488","GO:0004672(protein kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0005737(cytoplasm);GO:0005794(Golgi apparatus);GO:0043231(intracellular membrane-bounded organelle);GO:0000166(nucleotide binding);GO:0004674(protein serine/threonine kinase activity);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0005515(protein binding);GO:0006915(apoptotic process);GO:0031410(cytoplasmic vesicle);GO:0042802(identical protein binding);GO:0005516(calmodulin binding);GO:0018105(peptidyl-serine phosphorylation);GO:0042981(regulation of apoptotic process);GO:0046777(protein autophosphorylation);GO:0010506(regulation of autophagy);GO:0035556(intracellular signal transduction);GO:0018107(peptidyl-threonine phosphorylation);GO:0090023(positive regulation of neutrophil chemotaxis);GO:2001242(regulation of intrinsic apoptotic signaling pathway);GO:0043276(anoikis);GO:2000424(positive regulation of eosinophil chemotaxis);GO:0034423(autophagosome lumen);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:1990266(neutrophil migration);GO:1990266(neutrophil migration)","04140(Autophagy - animal);05200(Pathways in cancer);05219(Bladder cancer);05219(Bladder cancer)","K08803","EC:2.7.11.1","death associated protein kinase 2 [Source:HGNC Symbol;Acc:HGNC:2675]",{"v":0.459419799147811,"d":"0.46"},{"v":1.02375338811343,"d":"1.02"},{"v":0.448760223391718,"d":"0.45"},{"v":-1.1559832889466,"d":"-1.16"},{"v":0.0903595771441175,"d":"0.09"},{"v":0.819651875293549,"d":"0.82"},"down","no"]
["MSTRG.13193","OSTM1","ENST00000193322;ENST00000492130;ENST00000467960","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005765(lysosomal membrane);GO:0005764(lysosome);GO:0034220(ion transmembrane transport);GO:0030316(osteoclast differentiation);GO:0005829(cytosol);GO:0005829(cytosol)","NA","NA","NA","osteopetrosis associated transmembrane protein 1 [Source:HGNC Symbol;Acc:HGNC:21652]",{"v":3.02716971605634,"d":"3.03"},{"v":6.71741776938967,"d":"6.72"},{"v":0.450644848955313,"d":"0.45"},{"v":-1.14993719466152,"d":"-1.15"},{"v":0.0903917696719676,"d":"0.09"},{"v":0.819651875293549,"d":"0.82"},"down","no"]
["ENSG00000180921","FAM83H","ENST00000388913","GO:0005737(cytoplasm);GO:0005856(cytoskeleton);GO:0019901(protein kinase binding);GO:0031214(biomineral tissue development);GO:0030335(positive regulation of cell migration);GO:0045104(intermediate filament cytoskeleton organization);GO:1990254(keratin filament binding);GO:0045095(keratin filament);GO:0044380(protein localization to cytoskeleton)","NA","NA","NA","family with sequence similarity 83 member H [Source:HGNC Symbol;Acc:HGNC:24797]",{"v":0.301709,"d":"0.30"},{"v":0.134462,"d":"0.13"},{"v":2.2438235337865,"d":"2.24"},{"v":1.16595921919899,"d":"1.17"},{"v":0.0904780792255273,"d":"0.09"},{"v":0.819817178355004,"d":"0.82"},"up","no"]
["MSTRG.39","MTND2P28","ENST00000457540","NA","NA","NA","NA","mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 2 pseudogene 28 [Source:HGNC Symbol;Acc:HGNC:42129]",{"v":1497.060181,"d":"1497.06"},{"v":702.079834,"d":"702.08"},{"v":2.13232186498039,"d":"2.13"},{"v":1.09242522325807,"d":"1.09"},{"v":0.0906654463622411,"d":"0.09"},{"v":0.820528975344127,"d":"0.82"},"up","no"]
["MSTRG.4026","UCHL3;LMO7","ENST00000377595;ENST00000485987;ENST00000606347;ENST00000605961;ENST00000533305;ENST00000526202;ENST00000532785;ENST00000467686;ENST00000465261;ENST00000419068;ENST00000525914;ENST00000377534;ENST00000471792;ENST00000532377;ENST00000482116;ENST00000377499;ENST00000357063;ENST00000533299;ENST00000489941;ENST00000618773;ENST00000524651;ENST00000607339","GO:0005737(cytoplasm);GO:0005634(nucleus);GO:0005829(cytosol);GO:0004843(thiol-dependent ubiquitin-specific protease activity);GO:0016787(hydrolase activity);GO:0005622(intracellular);GO:0005515(protein binding);GO:0008233(peptidase activity);GO:0008234(cysteine-type peptidase activity);GO:0006508(proteolysis);GO:0006511(ubiquitin-dependent protein catabolic process);GO:0036459(thiol-dependent ubiquitinyl hydrolase activity);GO:0016567(protein ubiquitination);GO:0070062(extracellular exosome);GO:0016579(protein deubiquitination);GO:0043687(post-translational protein modification);GO:0043130(ubiquitin binding);GO:0030163(protein catabolic process);GO:0019784(NEDD8-specific protease activity);GO:0046872(metal ion binding);GO:0023051(regulation of signaling);GO:0005925(focal adhesion);GO:0030155(regulation of cell adhesion);GO:0000209(protein polyubiquitination);GO:0004842(ubiquitin-protein transferase activity);GO:0000151(ubiquitin ligase complex);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0008022(protein C-terminus binding);GO:0042805(actinin binding);GO:0016337(single organismal cell-cell adhesion);GO:0005913(cell-cell adherens junction);GO:0016324(apical plasma membrane);GO:0019784(NEDD8-specific protease activity)","04520(Adherens junction);04520(Adherens junction)","K06084","NA","ubiquitin C-terminal hydrolase L3 [Source:HGNC Symbol;Acc:HGNC:12515];LIM domain 7 [Source:HGNC Symbol;Acc:HGNC:6646]",{"v":0.717660381126594,"d":"0.72"},{"v":0.332976529240867,"d":"0.33"},{"v":2.15528819032003,"d":"2.16"},{"v":1.10788078947553,"d":"1.11"},{"v":0.0906929136508083,"d":"0.09"},{"v":0.820528975344127,"d":"0.82"},"up","no"]
["MSTRG.1426","H3F3A","ENST00000366815;ENST00000366813;ENST00000366814;ENST00000366816;MSTRG.1426.2","GO:0005634(nucleus);GO:0003677(DNA binding);GO:0046982(protein heterodimerization activity);GO:0006334(nucleosome assembly);GO:0000786(nucleosome);GO:0005694(chromosome);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0005654(nucleoplasm);GO:0070062(extracellular exosome);GO:0044267(cellular protein metabolic process);GO:1902036(regulation of hematopoietic stem cell differentiation);GO:0043234(protein complex);GO:0000784(nuclear chromosome, telomeric region);GO:0045815(positive regulation of gene expression, epigenetic);GO:0042393(histone binding);GO:0030307(positive regulation of cell growth);GO:0045652(regulation of megakaryocyte differentiation);GO:0006336(DNA replication-independent nucleosome assembly);GO:0007596(blood coagulation);GO:0000228(nuclear chromosome);GO:0060964(regulation of gene silencing by miRNA);GO:0000183(chromatin silencing at rDNA);GO:0045814(negative regulation of gene expression, epigenetic);GO:0000979(RNA polymerase II core promoter sequence-specific DNA binding);GO:0031492(nucleosomal DNA binding);GO:0000980(RNA polymerase II distal enhancer sequence-specific DNA binding);GO:0000788(nuclear nucleosome);GO:0032200(telomere organization);GO:0001649(osteoblast differentiation);GO:0006997(nucleus organization);GO:0007283(spermatogenesis);GO:0007286(spermatid development);GO:0007338(single fertilization);GO:0007420(brain development);GO:0007566(embryo implantation);GO:0008283(cell proliferation);GO:0008584(male gonad development);GO:0009725(response to hormone);GO:0031508(pericentric heterochromatin assembly);GO:0031509(telomeric heterochromatin assembly);GO:0035264(multicellular organism growth);GO:0042692(muscle cell differentiation);GO:0048477(oogenesis);GO:0090230(regulation of centromere complex assembly);GO:1902340(negative regulation of chromosome condensation);GO:0001740(Barr body);GO:0001740(Barr body)","05202(Transcriptional misregulation in cancers);05322(Systemic lupus erythematosus);05034(Alcoholism);05034(Alcoholism)","K11253","NA","H3 histone family member 3A [Source:HGNC Symbol;Acc:HGNC:4764]",{"v":36.8013471723181,"d":"36.80"},{"v":81.4064085123305,"d":"81.41"},{"v":0.452069411301247,"d":"0.45"},{"v":-1.1453837920435,"d":"-1.15"},{"v":0.0907629068494064,"d":"0.09"},{"v":0.820545738949363,"d":"0.82"},"down","no"]
["MSTRG.2664","NUMA1","ENST00000393695;MSTRG.2664.2;ENST00000545721;MSTRG.2664.1;ENST00000543009;ENST00000546036;ENST00000544129;ENST00000613205;ENST00000537930;ENST00000537905;ENST00000534987;ENST00000536119;ENST00000544238;ENST00000540843;ENST00000540588;ENST00000541262;ENST00000543450;ENST00000541641;ENST00000368959;ENST00000535838;ENST00000358965;ENST00000351960;ENST00000535087;ENST00000620566;ENST00000541584;ENST00000542977;ENST00000543937;ENST00000616538;ENST00000534971;ENST00000535111;ENST00000540626;MSTRG.2664.3","GO:0005654(nucleoplasm);GO:0000139(Golgi membrane);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005829(cytosol);GO:0051301(cell division);GO:0005694(chromosome);GO:0005886(plasma membrane);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0007049(cell cycle);GO:0005874(microtubule);GO:0008017(microtubule binding);GO:0000922(spindle pole);GO:0005813(centrosome);GO:0005815(microtubule organizing center);GO:0007059(chromosome segregation);GO:0008289(lipid binding);GO:0035091(phosphatidylinositol binding);GO:0070062(extracellular exosome);GO:0005938(cell cortex);GO:0070840(dynein complex binding);GO:0043234(protein complex);GO:0005876(spindle microtubule);GO:0019904(protein domain specific binding);GO:0016363(nuclear matrix);GO:0097431(mitotic spindle pole);GO:1990023(mitotic spindle midzone);GO:0015631(tubulin binding);GO:0005198(structural molecule activity);GO:0000132(establishment of mitotic spindle orientation);GO:0099738(cell cortex region);GO:0005819(spindle);GO:0006997(nucleus organization);GO:1904778(positive regulation of protein localization to cell cortex);GO:0001578(microtubule bundle formation);GO:0072686(mitotic spindle);GO:0051010(microtubule plus-end binding);GO:0045618(positive regulation of keratinocyte differentiation);GO:0097718(disordered domain specific binding);GO:0097427(microtubule bundle);GO:0036449(microtubule minus-end);GO:0008022(protein C-terminus binding);GO:0031616(spindle pole centrosome);GO:0031116(positive regulation of microtubule polymerization);GO:0030513(positive regulation of BMP signaling pathway);GO:0019897(extrinsic component of plasma membrane);GO:0030953(astral microtubule organization);GO:0035371(microtubule plus-end);GO:0060236(regulation of mitotic spindle organization);GO:1905832(positive regulation of spindle assembly);GO:0051011(microtubule minus-end binding);GO:0032388(positive regulation of intracellular transport);GO:0090235(regulation of metaphase plate congression);GO:0051798(positive regulation of hair follicle development);GO:0051984(positive regulation of chromosome segregation);GO:0055048(anastral spindle assembly);GO:1902365(positive regulation of protein localization to spindle pole body);GO:1902846(positive regulation of mitotic spindle elongation);GO:1905820(positive regulation of chromosome separation);GO:0055028(cortical microtubule);GO:0061673(mitotic spindle astral microtubule);GO:1905720(cytoplasmic microtubule bundle);GO:0051321(meiotic cell cycle);GO:0060487(lung epithelial cell differentiation);GO:0030425(dendrite);GO:0043025(neuronal cell body);GO:0045177(apical part of cell);GO:0045177(apical part of cell)","NA","NA","NA","nuclear mitotic apparatus protein 1 [Source:HGNC Symbol;Acc:HGNC:8059]",{"v":14.1074127549587,"d":"14.11"},{"v":6.61616845080315,"d":"6.62"},{"v":2.13226323662394,"d":"2.13"},{"v":1.09238555569975,"d":"1.09"},{"v":0.0910164657746601,"d":"0.09"},{"v":0.821315535536268,"d":"0.82"},"up","no"]
["ENSG00000248405","PRR5-ARHGAP8","ENST00000361473;ENST00000495250;ENST00000352766","GO:0007165(signal transduction);GO:0005737(cytoplasm);GO:0043087(regulation of GTPase activity);GO:0043087(regulation of GTPase activity)","NA","NA","NA","PRR5-ARHGAP8 readthrough [Source:HGNC Symbol;Acc:HGNC:34512]",{"v":0.572489820465686,"d":"0.57"},{"v":0.257800913602941,"d":"0.26"},{"v":2.22066637571123,"d":"2.22"},{"v":1.15099266426679,"d":"1.15"},{"v":0.0910355424655821,"d":"0.09"},{"v":0.821315535536268,"d":"0.82"},"up","no"]
["MSTRG.933","CERS2","ENST00000271688;ENST00000368954;MSTRG.933.7;ENST00000457392;ENST00000558062;ENST00000482825;ENST00000368949;ENST00000361419;ENST00000460664;ENST00000561294;ENST00000559660;ENST00000421609;ENST00000559020;ENST00000345896","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005783(endoplasmic reticulum);GO:0005634(nucleus);GO:0003677(DNA binding);GO:0006629(lipid metabolic process);GO:0005789(endoplasmic reticulum membrane);GO:0005515(protein binding);GO:0031965(nuclear membrane);GO:0030148(sphingolipid biosynthetic process);GO:0046513(ceramide biosynthetic process);GO:0050291(sphingosine N-acyltransferase activity);GO:0048681(negative regulation of axon regeneration);GO:1900148(negative regulation of Schwann cell migration);GO:1905045(negative regulation of Schwann cell proliferation involved in axon regeneration);GO:1905045(negative regulation of Schwann cell proliferation involved in axon regeneration)","00600(Sphingolipid metabolism);04071(Sphingolipid signaling pathway);04071(Sphingolipid signaling pathway)","K04710","EC:2.3.1.24","ceramide synthase 2 [Source:HGNC Symbol;Acc:HGNC:14076]",{"v":11.1912265698254,"d":"11.19"},{"v":24.7503785247298,"d":"24.75"},{"v":0.452163855136336,"d":"0.45"},{"v":-1.14508242367302,"d":"-1.15"},{"v":0.0910526689869555,"d":"0.09"},{"v":0.821315535536268,"d":"0.82"},"down","no"]
["ENSG00000107611","CUBN","ENST00000377833;ENST00000433666","GO:0006810(transport);GO:0016020(membrane);GO:0015031(protein transport);GO:0046872(metal ion binding);GO:0005509(calcium ion binding);GO:0005765(lysosomal membrane);GO:0006629(lipid metabolic process);GO:0042803(protein homodimerization activity);GO:0008202(steroid metabolic process);GO:0005886(plasma membrane);GO:0005905(clathrin-coated pit);GO:0008203(cholesterol metabolic process);GO:0005764(lysosome);GO:0005515(protein binding);GO:0005768(endosome);GO:0005829(cytosol);GO:0006897(endocytosis);GO:0070062(extracellular exosome);GO:0010008(endosome membrane);GO:0031419(cobalamin binding);GO:0016324(apical plasma membrane);GO:0005215(transporter activity);GO:0004872(receptor activity);GO:0043202(lysosomal lumen);GO:0031526(brush border membrane);GO:0031232(extrinsic component of external side of plasma membrane);GO:0009235(cobalamin metabolic process);GO:0030139(endocytic vesicle);GO:0042359(vitamin D metabolic process);GO:0001894(tissue homeostasis);GO:0006898(receptor-mediated endocytosis);GO:0015889(cobalamin transport);GO:0034384(high-density lipoprotein particle clearance);GO:0042953(lipoprotein transport);GO:0005737(cytoplasm);GO:0005783(endoplasmic reticulum);GO:0005794(Golgi apparatus);GO:0005903(brush border);GO:0045177(apical part of cell);GO:0045177(apical part of cell)","04977(Vitamin digestion and absorption);04977(Vitamin digestion and absorption)","K14616","NA","cubilin [Source:HGNC Symbol;Acc:HGNC:2548]",{"v":0.29466416441373,"d":"0.29"},{"v":0.135104098040705,"d":"0.14"},{"v":2.18101574035861,"d":"2.18"},{"v":1.12500018192518,"d":"1.13"},{"v":0.0911881117965331,"d":"0.09"},{"v":0.821921588513362,"d":"0.82"},"up","no"]
["MSTRG.3630","UHRF1BP1L","ENST00000547428;ENST00000279907;ENST00000551980;ENST00000548045;ENST00000545232;ENST00000547504;ENST00000356828;ENST00000550544;ENST00000548712","NA","NA","NA","NA","UHRF1 binding protein 1 like [Source:HGNC Symbol;Acc:HGNC:29102]",{"v":2.68361259537485,"d":"2.68"},{"v":5.95881683025998,"d":"5.96"},{"v":0.450359974441061,"d":"0.45"},{"v":-1.15084948070486,"d":"-1.15"},{"v":0.0913461143109142,"d":"0.09"},{"v":0.822677544067855,"d":"0.82"},"down","no"]
["ENSG00000152439","ZNF773","ENST00000597061;ENST00000593916;ENST00000598770;ENST00000599847;ENST00000282292;ENST00000601958","GO:0003676(nucleic acid binding);GO:0006355(regulation of transcription, DNA-templated);GO:0005622(intracellular);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0003677(DNA binding)","NA","NA","NA","zinc finger protein 773 [Source:HGNC Symbol;Acc:HGNC:30487]",{"v":0.234410023163632,"d":"0.23"},{"v":0.103359045584046,"d":"0.10"},{"v":2.26791977266298,"d":"2.27"},{"v":1.18136960605243,"d":"1.18"},{"v":0.091463456033735,"d":"0.09"},{"v":0.822677544067855,"d":"0.82"},"up","no"]
["MSTRG.5462","TM2D3","ENST00000347970;ENST00000560013;ENST00000560910;ENST00000619579;ENST00000559107;ENST00000428002;ENST00000559891;ENST00000560212;ENST00000559024;ENST00000333202;ENST00000560390;ENST00000560883;ENST00000558129;ENST00000561373;ENST00000561356","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016021(integral component of membrane)","NA","NA","NA","TM2 domain containing 3 [Source:HGNC Symbol;Acc:HGNC:24128]",{"v":0.397270817050614,"d":"0.40"},{"v":0.893264627963679,"d":"0.89"},{"v":0.444740343022703,"d":"0.44"},{"v":-1.16896481536348,"d":"-1.17"},{"v":0.0916077117790743,"d":"0.09"},{"v":0.822677544067855,"d":"0.82"},"down","no"]
["MSTRG.2443","TMEM138","ENST00000278826;ENST00000534963;ENST00000539776;ENST00000507563;ENST00000543833;ENST00000423772;ENST00000381787;ENST00000543594;ENST00000545420;ENST00000542946;ENST00000451389","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0042995(cell projection);GO:0060271(cilium assembly);GO:0005929(cilium);GO:0030030(cell projection organization);GO:0005773(vacuole);GO:0005774(vacuolar membrane);GO:0005774(vacuolar membrane)","NA","NA","NA","transmembrane protein 138 [Source:HGNC Symbol;Acc:HGNC:26944]",{"v":0.387614556868305,"d":"0.39"},{"v":0.87100820447385,"d":"0.87"},{"v":0.445018261455357,"d":"0.45"},{"v":-1.16806355617794,"d":"-1.17"},{"v":0.0916132847030958,"d":"0.09"},{"v":0.822677544067855,"d":"0.82"},"down","no"]
["ENSG00000178585","CTNNBIP1","ENST00000400904;ENST00000377263","GO:0005737(cytoplasm);GO:0043433(negative regulation of sequence-specific DNA binding transcription factor activity);GO:0005634(nucleus);GO:0008013(beta-catenin binding);GO:0005515(protein binding);GO:0016055(Wnt signaling pathway);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0001658(branching involved in ureteric bud morphogenesis);GO:0009952(anterior/posterior pattern specification);GO:0030178(negative regulation of Wnt signaling pathway);GO:0031333(negative regulation of protein complex assembly);GO:0043392(negative regulation of DNA binding);GO:0048662(negative regulation of smooth muscle cell proliferation);GO:0060633(negative regulation of transcription initiation from RNA polymerase II promoter);GO:0005654(nucleoplasm);GO:0070016(armadillo repeat domain binding);GO:0005829(cytosol);GO:0045669(positive regulation of osteoblast differentiation);GO:0032091(negative regulation of protein binding);GO:0030877(beta-catenin destruction complex);GO:0045657(positive regulation of monocyte differentiation);GO:0002528(regulation of vascular permeability involved in acute inflammatory response);GO:0072201(negative regulation of mesenchymal cell proliferation);GO:0072201(negative regulation of mesenchymal cell proliferation)","04310(Wnt signaling pathway);04310(Wnt signaling pathway)","K04493","NA","catenin beta interacting protein 1 [Source:HGNC Symbol;Acc:HGNC:16913]",{"v":1.73780267744834,"d":"1.74"},{"v":0.802234079065588,"d":"0.80"},{"v":2.16620400802777,"d":"2.17"},{"v":1.11516911898977,"d":"1.12"},{"v":0.0916135680613681,"d":"0.09"},{"v":0.822677544067855,"d":"0.82"},"up","no"]
["MSTRG.3083","EMG1;C1S","ENST00000599672;ENST00000539196;ENST00000495061;ENST00000406697;ENST00000495053;ENST00000611981;ENST00000470326;ENST00000620255;ENST00000607161;ENST00000473545;ENST00000261406;ENST00000443875;ENST00000461983","GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005730(nucleolus);GO:0008168(methyltransferase activity);GO:0016740(transferase activity);GO:0032259(methylation);GO:0005515(protein binding);GO:0042254(ribosome biogenesis);GO:0006364(rRNA processing);GO:0042274(ribosomal small subunit biogenesis);GO:0019843(rRNA binding);GO:0000462(maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA));GO:0070475(rRNA base methylation);GO:0032040(small-subunit processome);GO:0005654(nucleoplasm);GO:0070037(rRNA (pseudouridine) methyltransferase activity);GO:0046872(metal ion binding);GO:0016787(hydrolase activity);GO:0005509(calcium ion binding);GO:0008233(peptidase activity);GO:0006508(proteolysis);GO:0004252(serine-type endopeptidase activity);GO:0008236(serine-type peptidase activity);GO:0002376(immune system process);GO:0045087(innate immune response);GO:0006956(complement activation);GO:0006958(complement activation, classical pathway);GO:0030449(regulation of complement activation);GO:0005576(extracellular region);GO:0042802(identical protein binding);GO:0070062(extracellular exosome);GO:0072562(blood microparticle);GO:0001867(complement activation, lectin pathway);GO:0001867(complement activation, lectin pathway)","03008(Ribosome biogenesis in eukaryotes);04610(Complement and coagulation cascades);05322(Systemic lupus erythematosus);05133(Pertussis);05150(Staphylococcus aureus infection);05150(Staphylococcus aureus infection)","K14568","EC:2.1.1.260","EMG1, N1-specific pseudouridine methyltransferase [Source:HGNC Symbol;Acc:HGNC:16912];complement C1s [Source:HGNC Symbol;Acc:HGNC:1247]",{"v":0.429781021358291,"d":"0.43"},{"v":0.955975724102072,"d":"0.96"},{"v":0.449573153922894,"d":"0.45"},{"v":-1.15337220670103,"d":"-1.15"},{"v":0.0918131730576655,"d":"0.09"},{"v":0.823855610998814,"d":"0.82"},"down","no"]
["MSTRG.3812","AC084018.1;AC084018.2","ENST00000609067;ENST00000613093","NA","NA","NA","NA",null,{"v":4.61884743044796,"d":"4.62"},{"v":2.15920939912428,"d":"2.16"},{"v":2.13913825695704,"d":"2.14"},{"v":1.09702972989908,"d":"1.10"},{"v":0.0919008671712882,"d":"0.09"},{"v":0.824007105105556,"d":"0.82"},"up","no"]
["ENSG00000140090","SLC24A4","ENST00000532405;ENST00000531433;ENST00000525557;ENST00000556739;ENST00000554925;ENST00000526482","GO:0006810(transport);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0055085(transmembrane transport);GO:0006811(ion transport);GO:0005887(integral component of plasma membrane);GO:0015293(symporter activity);GO:0006813(potassium ion transport);GO:0005886(plasma membrane);GO:0015297(antiporter activity);GO:0006814(sodium ion transport);GO:0035725(sodium ion transmembrane transport);GO:0006816(calcium ion transport);GO:0007608(sensory perception of smell);GO:0050896(response to stimulus);GO:0005509(calcium ion binding);GO:0008273(calcium, potassium:sodium antiporter activity);GO:0005262(calcium channel activity);GO:0030955(potassium ion binding);GO:0031402(sodium ion binding);GO:0006874(cellular calcium ion homeostasis);GO:0097186(amelogenesis);GO:0070588(calcium ion transmembrane transport);GO:0070588(calcium ion transmembrane transport)","04740(Olfactory transduction);04740(Olfactory transduction)","K13752","NA","solute carrier family 24 member 4 [Source:HGNC Symbol;Acc:HGNC:10978]",{"v":0.360994113794061,"d":"0.36"},{"v":0.803450290105468,"d":"0.80"},{"v":0.449304852135499,"d":"0.45"},{"v":-1.15423345298144,"d":"-1.15"},{"v":0.0920357999540797,"d":"0.09"},{"v":0.824007105105556,"d":"0.82"},"down","no"]
["ENSG00000176593","AC008969.1","ENST00000546949;ENST00000546956;ENST00000550135;ENST00000313957","NA","NA","NA","NA",null,{"v":0.398734823489245,"d":"0.40"},{"v":0.181629447593035,"d":"0.18"},{"v":2.19532035566536,"d":"2.20"},{"v":1.13443148272475,"d":"1.13"},{"v":0.092056570290174,"d":"0.09"},{"v":0.824007105105556,"d":"0.82"},"up","no"]
["MSTRG.12619","IRF4","ENST00000380956;ENST00000495137;ENST00000469834;ENST00000493114;ENST00000468485","GO:0005634(nucleus);GO:0016020(membrane);GO:0005654(nucleoplasm);GO:0006355(regulation of transcription, DNA-templated);GO:0006366(transcription from RNA polymerase II promoter);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0005515(protein binding);GO:0045893(positive regulation of transcription, DNA-templated);GO:0000975(regulatory region DNA binding);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:0005829(cytosol);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0043565(sequence-specific DNA binding);GO:0008134(transcription factor binding);GO:0042110(T cell activation);GO:0060333(interferon-gamma-mediated signaling pathway);GO:0001077(transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0060337(type I interferon signaling pathway);GO:0045086(positive regulation of interleukin-2 biosynthetic process);GO:0042832(defense response to protozoan);GO:0072540(T-helper 17 cell lineage commitment);GO:0045404(positive regulation of interleukin-4 biosynthetic process);GO:0016279(protein-lysine N-methyltransferase activity);GO:0006479(protein methylation);GO:0018022(peptidyl-lysine methylation);GO:0034122(negative regulation of toll-like receptor signaling pathway);GO:0043011(myeloid dendritic cell differentiation);GO:0043388(positive regulation of DNA binding);GO:0043966(histone H3 acetylation);GO:0043967(histone H4 acetylation);GO:0045082(positive regulation of interleukin-10 biosynthetic process);GO:0045368(positive regulation of interleukin-13 biosynthetic process);GO:0045622(regulation of T-helper cell differentiation);GO:0000788(nuclear nucleosome);GO:0000788(nuclear nucleosome)","04659(Th17 cell differentiation);04659(Th17 cell differentiation)","K09445","NA","interferon regulatory factor 4 [Source:HGNC Symbol;Acc:HGNC:6119]",{"v":5.86063632587318,"d":"5.86"},{"v":2.75258032316039,"d":"2.75"},{"v":2.12914270895618,"d":"2.13"},{"v":1.09027265181149,"d":"1.09"},{"v":0.0921037671044742,"d":"0.09"},{"v":0.824007105105556,"d":"0.82"},"up","no"]
["MSTRG.14603","DENND3","ENST00000517813;ENST00000519811;ENST00000523530;ENST00000520482;ENST00000262585;ENST00000521835;ENST00000518198;ENST00000518806;ENST00000518347;ENST00000517985;ENST00000424248;ENST00000518668;ENST00000519291;ENST00000520725;ENST00000521477;ENST00000523066;ENST00000523015;ENST00000523058;ENST00000523308;ENST00000518249;ENST00000520986;ENST00000520571","GO:0043547(positive regulation of GTPase activity);GO:0005085(guanyl-nucleotide exchange factor activity);GO:0005829(cytosol);GO:0017112(Rab guanyl-nucleotide exchange factor activity);GO:0008333(endosome to lysosome transport);GO:0044257(cellular protein catabolic process);GO:0061024(membrane organization);GO:0061024(membrane organization)","NA","NA","NA","DENN domain containing 3 [Source:HGNC Symbol;Acc:HGNC:29134]",{"v":3.9680772595092,"d":"3.97"},{"v":8.75585524996592,"d":"8.76"},{"v":0.453191281288558,"d":"0.45"},{"v":-1.14180798872177,"d":"-1.14"},{"v":0.0923534464508662,"d":"0.09"},{"v":0.825627470052956,"d":"0.83"},"down","no"]
["MSTRG.5025","WDR76","ENST00000263795;ENST00000381246;ENST00000452115","GO:0006974(cellular response to DNA damage stimulus);GO:0005634(nucleus);GO:0003677(DNA binding);GO:2000001(regulation of DNA damage checkpoint);GO:2000001(regulation of DNA damage checkpoint)","NA","NA","NA","WD repeat domain 76 [Source:HGNC Symbol;Acc:HGNC:25773]",{"v":1.81865843158411,"d":"1.82"},{"v":0.844145980872977,"d":"0.84"},{"v":2.15443593026805,"d":"2.15"},{"v":1.10731019547362,"d":"1.11"},{"v":0.0926016367490561,"d":"0.09"},{"v":0.826485982438,"d":"0.83"},"up","no"]
["MSTRG.10993","SMIM4","ENST00000477703;ENST00000307106;ENST00000476842;ENST00000491607","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005739(mitochondrion);GO:0005739(mitochondrion)","NA","NA","NA","small integral membrane protein 4 [Source:HGNC Symbol;Acc:HGNC:37257]",{"v":0.852273562449637,"d":"0.85"},{"v":0.386142401289283,"d":"0.39"},{"v":2.2071483463199,"d":"2.21"},{"v":1.14218359894585,"d":"1.14"},{"v":0.0926330902338423,"d":"0.09"},{"v":0.826485982438,"d":"0.83"},"up","no"]
["MSTRG.12667","TXNDC5;EEF1E1;BLOC1S5;EEF1E1-BLOC1S5;BLOC1S5-TXNDC5","ENST00000379757;ENST00000379715;ENST00000397457;ENST00000475802;ENST00000502429;ENST00000460138;ENST00000397456;ENST00000244777;ENST00000439343;ENST00000469459;ENST00000473453;ENST00000488226;ENST00000507463;ENST00000475998;ENST00000515633;ENST00000429723;ENST00000543936;ENST00000627748","GO:0005783(endoplasmic reticulum);GO:0016853(isomerase activity);GO:0045454(cell redox homeostasis);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0005788(endoplasmic reticulum lumen);GO:0070062(extracellular exosome);GO:0043312(neutrophil degranulation);GO:0043066(negative regulation of apoptotic process);GO:0043202(lysosomal lumen);GO:0035578(azurophil granule lumen);GO:0006457(protein folding);GO:0003756(protein disulfide isomerase activity);GO:0034976(response to endoplasmic reticulum stress);GO:0043277(apoptotic cell clearance);GO:0005623(cell);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0006412(translation);GO:0005730(nucleolus);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0008285(negative regulation of cell proliferation);GO:0043065(positive regulation of apoptotic process);GO:0004364(glutathione transferase activity);GO:0006749(glutathione metabolic process);GO:0006418(tRNA aminoacylation for protein translation);GO:0043517(positive regulation of DNA damage response, signal transduction by p53 class mediator);GO:2000774(positive regulation of cellular senescence);GO:0017101(aminoacyl-tRNA synthetase multienzyme complex);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0043231(intracellular membrane-bounded organelle);GO:1904115(axon cytoplasm);GO:0031083(BLOC-1 complex);GO:0030133(transport vesicle);GO:0008089(anterograde axonal transport);GO:0032438(melanosome organization);GO:0048490(anterograde synaptic vesicle transport);GO:0031175(neuron projection development);GO:0035646(endosome to melanosome transport);GO:0032402(melanosome transport);GO:0050942(positive regulation of pigment cell differentiation);GO:0050942(positive regulation of pigment cell differentiation)","04141(Protein processing in endoplasmic reticulum);04141(Protein processing in endoplasmic reticulum)","K13984","NA","thioredoxin domain containing 5 [Source:HGNC Symbol;Acc:HGNC:21073];eukaryotic translation elongation factor 1 epsilon 1 [Source:HGNC Symbol;Acc:HGNC:3212];biogenesis of lysosomal organelles complex 1 subunit 5 [Source:HGNC Symbol;Acc:HGNC:18561];EEF1E1-BLOC1S5 readthrough (NMD candidate) [Source:HGNC Symbol;Acc:HGNC:49187];BLOC1S5-TXNDC5 readthrough (NMD candidate) [Source:HGNC Symbol;Acc:HGNC:42001]",{"v":11.2650526493017,"d":"11.27"},{"v":5.29962432368233,"d":"5.30"},{"v":2.12563230170142,"d":"2.13"},{"v":1.08789205670393,"d":"1.09"},{"v":0.0926553791970852,"d":"0.09"},{"v":0.826485982438,"d":"0.83"},"up","no"]
["MSTRG.13788","ZNF394","ENST00000337673;ENST00000481881;ENST00000426306;ENST00000485576;ENST00000464401;ENST00000394177;ENST00000462024","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0005622(intracellular);GO:0005515(protein binding);GO:0005515(protein binding)","NA","NA","NA","zinc finger protein 394 [Source:HGNC Symbol;Acc:HGNC:18832]",{"v":1.94611144564907,"d":"1.95"},{"v":4.31701651554922,"d":"4.32"},{"v":0.450800092758385,"d":"0.45"},{"v":-1.14944028252264,"d":"-1.15"},{"v":0.0927577727849944,"d":"0.09"},{"v":0.826786898502519,"d":"0.83"},"down","no"]
["ENSG00000116138","DNAJC16","ENST00000616884;ENST00000375838;ENST00000490811;ENST00000479655;ENST00000375849;ENST00000375847;ENST00000483270","GO:0005623(cell);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0045454(cell redox homeostasis);GO:0005829(cytosol);GO:0005829(cytosol)","NA","NA","NA","DnaJ heat shock protein family (Hsp40) member C16 [Source:HGNC Symbol;Acc:HGNC:29157]",{"v":1.48439193868971,"d":"1.48"},{"v":0.691365838491183,"d":"0.69"},{"v":2.14704264522124,"d":"2.15"},{"v":1.1023508467338,"d":"1.10"},{"v":0.0930211811069377,"d":"0.09"},{"v":0.827720611556723,"d":"0.83"},"up","no"]
["MSTRG.7063","RNF43;SUPT4H1","MSTRG.7063.1;ENST00000225504;ENST00000577396;ENST00000581166;ENST00000581540;ENST00000579289;ENST00000582293;ENST00000581204;ENST00000580947","GO:0005634(nucleus);GO:0008270(zinc ion binding);GO:0006355(regulation of transcription, DNA-templated);GO:0032786(positive regulation of DNA-templated transcription, elongation);GO:0046872(metal ion binding);GO:0006351(transcription, DNA-templated);GO:0005515(protein binding);GO:0006368(transcription elongation from RNA polymerase II promoter);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0005654(nucleoplasm);GO:0003727(single-stranded RNA binding);GO:0046982(protein heterodimerization activity);GO:0006366(transcription from RNA polymerase II promoter);GO:0032785(negative regulation of DNA-templated transcription, elongation);GO:0050434(positive regulation of viral transcription);GO:0032044(DSIF complex);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0006338(chromatin remodeling);GO:0000993(RNA polymerase II core binding);GO:0006397(mRNA processing);GO:0034243(regulation of transcription elongation from RNA polymerase II promoter);GO:0034244(negative regulation of transcription elongation from RNA polymerase II promoter);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016740(transferase activity);GO:0016567(protein ubiquitination);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005886(plasma membrane);GO:0016055(Wnt signaling pathway);GO:0005887(integral component of plasma membrane);GO:0030178(negative regulation of Wnt signaling pathway);GO:0042787(protein ubiquitination involved in ubiquitin-dependent protein catabolic process);GO:0004842(ubiquitin-protein transferase activity);GO:0005635(nuclear envelope);GO:0005109(frizzled binding);GO:0061630(ubiquitin protein ligase activity);GO:0072089(stem cell proliferation);GO:0038018(Wnt receptor catabolic process);GO:0034244(negative regulation of transcription elongation from RNA polymerase II promoter)","NA","NA","NA","SPT4 homolog, DSIF elongation factor subunit [Source:HGNC Symbol;Acc:HGNC:11467];ring finger protein 43 [Source:HGNC Symbol;Acc:HGNC:18505]",{"v":1.22053444963688,"d":"1.22"},{"v":2.69510770682033,"d":"2.70"},{"v":0.452870379372281,"d":"0.45"},{"v":-1.1428299139233,"d":"-1.14"},{"v":0.0930229661054183,"d":"0.09"},{"v":0.827720611556723,"d":"0.83"},"down","no"]
["MSTRG.11278","GPR171","ENST00000309180","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0004930(G-protein coupled receptor activity);GO:0007186(G-protein coupled receptor signaling pathway);GO:0005886(plasma membrane);GO:0004871(signal transducer activity);GO:0007165(signal transduction);GO:0035589(G-protein coupled purinergic nucleotide receptor signaling pathway);GO:0005887(integral component of plasma membrane);GO:0045028(G-protein coupled purinergic nucleotide receptor activity);GO:0045638(negative regulation of myeloid cell differentiation)","NA","NA","NA","G protein-coupled receptor 171 [Source:HGNC Symbol;Acc:HGNC:30057]",{"v":1.99880861615599,"d":"2.00"},{"v":4.45630481671309,"d":"4.46"},{"v":0.448534985456916,"d":"0.45"},{"v":-1.15670757601551,"d":"-1.16"},{"v":0.0930687350978079,"d":"0.09"},{"v":0.827720611556723,"d":"0.83"},"down","no"]
["MSTRG.10194","IGLV1-44","ENST00000390297","GO:0016020(membrane);GO:0005886(plasma membrane);GO:0005576(extracellular region);GO:0006508(proteolysis);GO:0006955(immune response);GO:0002376(immune system process);GO:0003823(antigen binding);GO:0002250(adaptive immune response);GO:0004252(serine-type endopeptidase activity);GO:0006898(receptor-mediated endocytosis);GO:0006956(complement activation);GO:0006958(complement activation, classical pathway);GO:0030449(regulation of complement activation);GO:0038095(Fc-epsilon receptor signaling pathway);GO:0038096(Fc-gamma receptor signaling pathway involved in phagocytosis);GO:0050776(regulation of immune response);GO:0050900(leukocyte migration)","NA","NA","NA","immunoglobulin lambda variable 1-44 [Source:HGNC Symbol;Acc:HGNC:5879]",{"v":20.024843,"d":"20.02"},{"v":9.366352,"d":"9.37"},{"v":2.13795541743466,"d":"2.14"},{"v":1.09623176900016,"d":"1.10"},{"v":0.0931846829920004,"d":"0.09"},{"v":0.82814018641304,"d":"0.83"},"up","no"]
["MSTRG.6919","AC008105.3","ENST00000591365;ENST00000585471;ENST00000590522;ENST00000590495;ENST00000586376","NA","NA","NA","NA",null,{"v":3.2720435600968,"d":"3.27"},{"v":1.53133741005647,"d":"1.53"},{"v":2.13672280100317,"d":"2.14"},{"v":1.0953997579942,"d":"1.10"},{"v":0.0933534637697815,"d":"0.09"},{"v":0.829028326486511,"d":"0.83"},"up","no"]
["MSTRG.7504","C18orf25","ENST00000615052;ENST00000619301;ENST00000587591;ENST00000615553;ENST00000619230;ENST00000588730","GO:0016874(ligase activity);GO:0005515(protein binding);GO:0061630(ubiquitin protein ligase activity);GO:0043161(proteasome-mediated ubiquitin-dependent protein catabolic process);GO:0042787(protein ubiquitination involved in ubiquitin-dependent protein catabolic process);GO:0000209(protein polyubiquitination);GO:0000209(protein polyubiquitination)","NA","NA","NA","chromosome 18 open reading frame 25 [Source:HGNC Symbol;Acc:HGNC:28172]",{"v":1.0771790914787,"d":"1.08"},{"v":2.37744452057226,"d":"2.38"},{"v":0.453082745846544,"d":"0.45"},{"v":-1.14215354324505,"d":"-1.14"},{"v":0.0935801542899235,"d":"0.09"},{"v":0.829233733452163,"d":"0.83"},"down","no"]
["MSTRG.5406","ANPEP","ENST00000300060;ENST00000559874;MSTRG.5406.1;ENST00000558177;ENST00000560137;ENST00000559887;ENST00000560030;ENST00000559761;ENST00000560028;ENST00000558740","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0005634(nucleus);GO:0016787(hydrolase activity);GO:0005765(lysosomal membrane);GO:0005886(plasma membrane);GO:0008233(peptidase activity);GO:0006508(proteolysis);GO:0007275(multicellular organism development);GO:0005615(extracellular space);GO:0030154(cell differentiation);GO:0008237(metallopeptidase activity);GO:0004177(aminopeptidase activity);GO:0009897(external side of plasma membrane);GO:0046718(viral entry into host cell);GO:0070062(extracellular exosome);GO:0007165(signal transduction);GO:0007267(cell-cell signaling);GO:0016032(viral process);GO:0043312(neutrophil degranulation);GO:0004872(receptor activity);GO:0030667(secretory granule membrane);GO:0001525(angiogenesis);GO:0001618(virus receptor activity);GO:0005793(endoplasmic reticulum-Golgi intermediate compartment);GO:0042277(peptide binding);GO:0070006(metalloaminopeptidase activity);GO:0008217(regulation of blood pressure);GO:0043171(peptide catabolic process);GO:0043171(peptide catabolic process)","00480(Glutathione metabolism);04640(Hematopoietic cell lineage);04614(Renin-angiotensin system);04614(Renin-angiotensin system)","K11140","EC:3.4.11.2","alanyl aminopeptidase, membrane [Source:HGNC Symbol;Acc:HGNC:500]",{"v":36.6422217458427,"d":"36.64"},{"v":80.493333959146,"d":"80.49"},{"v":0.455220574717905,"d":"0.46"},{"v":-1.13536232992151,"d":"-1.14"},{"v":0.0935860241047126,"d":"0.09"},{"v":0.829233733452163,"d":"0.83"},"down","no"]
["ENSG00000066279","ASPM","ENST00000367409;ENST00000294732","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0051301(cell division);GO:0005856(cytoskeleton);GO:0007049(cell cycle);GO:0005819(spindle);GO:0007051(spindle organization);GO:0005516(calmodulin binding);GO:0001764(neuron migration);GO:0002052(positive regulation of neuroblast proliferation);GO:0007283(spermatogenesis);GO:0007420(brain development);GO:0008584(male gonad development);GO:0021873(forebrain neuroblast division);GO:0021987(cerebral cortex development);GO:0045665(negative regulation of neuron differentiation);GO:0045769(negative regulation of asymmetric cell division);GO:0048477(oogenesis);GO:0048589(developmental growth);GO:0051445(regulation of meiotic cell cycle);GO:0051653(spindle localization);GO:0051661(maintenance of centrosome location);GO:0090263(positive regulation of canonical Wnt signaling pathway);GO:0090306(spindle assembly involved in meiosis);GO:0097150(neuronal stem cell population maintenance);GO:0000922(spindle pole);GO:0005874(microtubule);GO:0030496(midbody);GO:0036449(microtubule minus-end);GO:0072687(meiotic spindle);GO:0097431(mitotic spindle pole);GO:0097431(mitotic spindle pole)","NA","NA","NA","abnormal spindle microtubule assembly [Source:HGNC Symbol;Acc:HGNC:19048]",{"v":0.29257,"d":"0.29"},{"v":0.134187242491044,"d":"0.13"},{"v":2.18031158975136,"d":"2.18"},{"v":1.12453432622528,"d":"1.12"},{"v":0.0936212816894779,"d":"0.09"},{"v":0.829233733452163,"d":"0.83"},"up","no"]
["MSTRG.7304","AC087741.1","ENST00000572730;ENST00000570309;ENST00000573346;ENST00000576824;ENST00000573935","NA","NA","NA","NA",null,{"v":1.23353210523233,"d":"1.23"},{"v":0.574033621632175,"d":"0.57"},{"v":2.14888476693225,"d":"2.15"},{"v":1.10358812090774,"d":"1.10"},{"v":0.0936758622703797,"d":"0.09"},{"v":0.829233733452163,"d":"0.83"},"up","no"]
["MSTRG.12745","BTN3A2","ENST00000508906;ENST00000604202;ENST00000528222;ENST00000396948;ENST00000530653;ENST00000356386;ENST00000377708;ENST00000396934;ENST00000524682;ENST00000532865;ENST00000527422;ENST00000527639;ENST00000527417;ENST00000528541;ENST00000531055;ENST00000532294;ENST00000532627","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005886(plasma membrane);GO:0002376(immune system process);GO:0002250(adaptive immune response);GO:0002456(T cell mediated immunity);GO:0072643(interferon-gamma secretion);GO:0072643(interferon-gamma secretion)","NA","NA","NA","butyrophilin subfamily 3 member A2 [Source:HGNC Symbol;Acc:HGNC:1139]",{"v":26.258480751207,"d":"26.26"},{"v":12.3929637425447,"d":"12.39"},{"v":2.11882171986531,"d":"2.12"},{"v":1.08326220277067,"d":"1.08"},{"v":0.0937209027759836,"d":"0.09"},{"v":0.829233733452163,"d":"0.83"},"up","no"]
["MSTRG.9265","NFE2L2;AC019080.1","ENST00000397062;ENST00000397063;ENST00000421929;ENST00000588123;ENST00000447413;ENST00000462023;ENST00000458603;ENST00000477534;ENST00000448782;ENST00000449627;ENST00000423513;ENST00000430047;ENST00000397057;ENST00000430416;ENST00000586532;ENST00000611493","GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0005634(nucleus);GO:0071356(cellular response to tumor necrosis factor);GO:2000352(negative regulation of endothelial cell apoptotic process);GO:0005737(cytoplasm);GO:0005794(Golgi apparatus);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0016567(protein ubiquitination);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0005886(plasma membrane);GO:0005813(centrosome);GO:0005515(protein binding);GO:0034599(cellular response to oxidative stress);GO:0019904(protein domain specific binding);GO:0006366(transcription from RNA polymerase II promoter);GO:0043161(proteasome-mediated ubiquitin-dependent protein catabolic process);GO:0001102(RNA polymerase II activating transcription factor binding);GO:0010499(proteasomal ubiquitin-independent protein catabolic process);GO:1903206(negative regulation of hydrogen peroxide-induced cell death);GO:0071498(cellular response to fluid shear stress);GO:0071499(cellular response to laminar fluid shear stress);GO:1903071(positive regulation of ER-associated ubiquitin-dependent protein catabolic process);GO:0000976(transcription regulatory region sequence-specific DNA binding);GO:0010628(positive regulation of gene expression);GO:1902176(negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway);GO:0036499(PERK-mediated unfolded protein response);GO:0070301(cellular response to hydrogen peroxide);GO:0044212(transcription regulatory region DNA binding);GO:0036003(positive regulation of transcription from RNA polymerase II promoter in response to stress);GO:0032993(protein-DNA complex);GO:0030968(endoplasmic reticulum unfolded protein response);GO:0000980(RNA polymerase II distal enhancer sequence-specific DNA binding);GO:0001205(transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding);GO:0001221(transcription cofactor binding);GO:0008134(transcription factor binding);GO:0043565(sequence-specific DNA binding);GO:0006954(inflammatory response);GO:0007568(aging);GO:0010667(negative regulation of cardiac muscle cell apoptotic process);GO:0010976(positive regulation of neuron projection development);GO:0030194(positive regulation of blood coagulation);GO:0034976(response to endoplasmic reticulum stress);GO:0035690(cellular response to drug);GO:0036091(positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress);GO:0042149(cellular response to glucose starvation);GO:0043536(positive regulation of blood vessel endothelial cell migration);GO:0045454(cell redox homeostasis);GO:0045766(positive regulation of angiogenesis);GO:0045893(positive regulation of transcription, DNA-templated);GO:0045995(regulation of embryonic development);GO:0046223(aflatoxin catabolic process);GO:0046326(positive regulation of glucose import);GO:0060548(negative regulation of cell death);GO:0071456(cellular response to hypoxia);GO:1902037(negative regulation of hematopoietic stem cell differentiation);GO:1903788(positive regulation of glutathione biosynthetic process);GO:1904753(negative regulation of vascular associated smooth muscle cell migration);GO:2000121(regulation of removal of superoxide radicals);GO:2000379(positive regulation of reactive oxygen species metabolic process);GO:0000785(chromatin);GO:0000785(chromatin)","04141(Protein processing in endoplasmic reticulum);05200(Pathways in cancer);05225(Hepatocellular carcinoma);05418(Fluid shear stress and atherosclerosis);05418(Fluid shear stress and atherosclerosis)","K05638","NA","nuclear factor, erythroid 2 like 2 [Source:HGNC Symbol;Acc:HGNC:7782]",{"v":1.99850072908399,"d":"2.00"},{"v":4.39477420171958,"d":"4.39"},{"v":0.454744803112301,"d":"0.45"},{"v":-1.13687094423864,"d":"-1.14"},{"v":0.0938865416360135,"d":"0.09"},{"v":0.830089379134269,"d":"0.83"},"down","no"]
["MSTRG.11156","ABTB1","ENST00000475042;ENST00000468137;ENST00000466612;ENST00000453791;ENST00000464431;ENST00000232744;ENST00000474129;ENST00000475265;ENST00000478298;ENST00000483857;ENST00000497162;ENST00000493365;ENST00000467179;ENST00000479280","GO:0005737(cytoplasm);GO:0006412(translation);GO:0005730(nucleolus);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0003746(translation elongation factor activity);GO:0006414(translational elongation);GO:0031625(ubiquitin protein ligase binding);GO:0043161(proteasome-mediated ubiquitin-dependent protein catabolic process);GO:0030162(regulation of proteolysis);GO:0042787(protein ubiquitination involved in ubiquitin-dependent protein catabolic process);GO:0019005(SCF ubiquitin ligase complex);GO:0019005(SCF ubiquitin ligase complex)","NA","NA","NA","ankyrin repeat and BTB domain containing 1 [Source:HGNC Symbol;Acc:HGNC:18275]",{"v":17.1037981431127,"d":"17.10"},{"v":37.5508695836721,"d":"37.55"},{"v":0.455483410444103,"d":"0.46"},{"v":-1.13452958554911,"d":"-1.13"},{"v":0.0941084301687613,"d":"0.09"},{"v":0.83047186623832,"d":"0.83"},"down","no"]
["MSTRG.1150","UHMK1","ENST00000489294;ENST00000282169;ENST00000545294","GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005794(Golgi apparatus);GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0005654(nucleoplasm);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0005515(protein binding);GO:0030628(pre-mRNA 3'-splice site binding);GO:0089701(U2AF);GO:0030424(axon);GO:0043021(ribonucleoprotein complex binding);GO:0018105(peptidyl-serine phosphorylation);GO:0071004(U2-type prespliceosome);GO:0045948(positive regulation of translational initiation);GO:0046777(protein autophosphorylation);GO:0032839(dendrite cytoplasm);GO:0031175(neuron projection development);GO:0007050(cell cycle arrest);GO:0000243(commitment complex);GO:0016607(nuclear speck);GO:0008187(poly-pyrimidine tract binding);GO:0046825(regulation of protein export from nucleus);GO:0035770(ribonucleoprotein granule);GO:0071598(neuronal ribonucleoprotein granule);GO:0071598(neuronal ribonucleoprotein granule)","NA","NA","NA","U2AF homology motif kinase 1 [Source:HGNC Symbol;Acc:HGNC:19683]",{"v":2.97473911031798,"d":"2.97"},{"v":6.53358020992862,"d":"6.53"},{"v":0.455300006235093,"d":"0.46"},{"v":-1.1351106157733,"d":"-1.14"},{"v":0.0941159990395983,"d":"0.09"},{"v":0.83047186623832,"d":"0.83"},"down","no"]
["MSTRG.5699","AC026401.3","ENST00000624682","NA","NA","NA","NA",null,{"v":0.860003,"d":"0.86"},{"v":2.001174,"d":"2.00"},{"v":0.429749237197765,"d":"0.43"},{"v":-1.21843301595652,"d":"-1.22"},{"v":0.0941851717962962,"d":"0.09"},{"v":0.83047186623832,"d":"0.83"},"down","no"]
["ENSG00000135976","ANKRD36","ENST00000420699;ENST00000452478;ENST00000494336;ENST00000461153;ENST00000620383;ENST00000639751;ENST00000421946","NA","NA","NA","NA","ankyrin repeat domain 36 [Source:HGNC Symbol;Acc:HGNC:24079]",{"v":0.709817376546365,"d":"0.71"},{"v":0.32971391626623,"d":"0.33"},{"v":2.15282807769999,"d":"2.15"},{"v":1.10623311218832,"d":"1.11"},{"v":0.0942056609601018,"d":"0.09"},{"v":0.83047186623832,"d":"0.83"},"up","no"]
["MSTRG.15517","G6PD","ENST00000393564;ENST00000393562;ENST00000439227;ENST00000369620;ENST00000489497;ENST00000490651;ENST00000488434;ENST00000497281;ENST00000433845","GO:0016020(membrane);GO:0016491(oxidoreductase activity);GO:0050661(NADP binding);GO:0055114(oxidation-reduction process);GO:0005515(protein binding);GO:0005975(carbohydrate metabolic process);GO:0042802(identical protein binding);GO:0006006(glucose metabolic process);GO:0006098(pentose-phosphate shunt);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0021762(substantia nigra development);GO:0004345(glucose-6-phosphate dehydrogenase activity);GO:0042803(protein homodimerization activity);GO:0009898(cytoplasmic side of plasma membrane);GO:0006629(lipid metabolic process);GO:0006749(glutathione metabolic process);GO:0005536(glucose binding);GO:0030246(carbohydrate binding);GO:0006695(cholesterol biosynthetic process);GO:0006739(NADP metabolic process);GO:0006740(NADPH regeneration);GO:0009051(pentose-phosphate shunt, oxidative branch);GO:0010041(response to iron(III) ion);GO:0010734(negative regulation of protein glutathionylation);GO:0014070(response to organic cyclic compound);GO:0019322(pentose biosynthetic process);GO:0032094(response to food);GO:0034599(cellular response to oxidative stress);GO:0043249(erythrocyte maturation);GO:0043523(regulation of neuron apoptotic process);GO:0045471(response to ethanol);GO:0046390(ribose phosphate biosynthetic process);GO:0051156(glucose 6-phosphate metabolic process);GO:0061052(negative regulation of cell growth involved in cardiac muscle cell development);GO:1904879(positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel);GO:2000378(negative regulation of reactive oxygen species metabolic process);GO:0005634(nucleus);GO:0043231(intracellular membrane-bounded organelle);GO:0043231(intracellular membrane-bounded organelle)","00030(Pentose phosphate pathway);00480(Glutathione metabolism);05230(Central carbon metabolism in cancer);05230(Central carbon metabolism in cancer)","K00036","EC:1.1.1.49;EC:1.1.1.363","glucose-6-phosphate dehydrogenase [Source:HGNC Symbol;Acc:HGNC:4057]",{"v":12.3524410582367,"d":"12.35"},{"v":27.0965287967107,"d":"27.10"},{"v":0.455868024679832,"d":"0.46"},{"v":-1.13331187509823,"d":"-1.13"},{"v":0.094663256213823,"d":"0.09"},{"v":0.833461713325231,"d":"0.83"},"down","no"]
["MSTRG.15004","ZDHHC12","ENST00000372663;ENST00000467312;ENST00000452105;ENST00000406904","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016740(transferase activity);GO:0005794(Golgi apparatus);GO:0016746(transferase activity, transferring acyl groups);GO:0019706(protein-cysteine S-palmitoyltransferase activity);GO:0005783(endoplasmic reticulum);GO:0016409(palmitoyltransferase activity);GO:0018345(protein palmitoylation);GO:0018345(protein palmitoylation)","NA","NA","NA","zinc finger DHHC-type containing 12 [Source:HGNC Symbol;Acc:HGNC:19159]",{"v":3.42071886176357,"d":"3.42"},{"v":7.55344392106276,"d":"7.55"},{"v":0.45286877052531,"d":"0.45"},{"v":-1.14283503918601,"d":"-1.14"},{"v":0.0947661830330874,"d":"0.09"},{"v":0.833461713325231,"d":"0.83"},"down","no"]
["ENSG00000130653","PNPLA7","ENST00000277531;ENST00000469998;ENST00000434090;ENST00000406427;ENST00000492278;ENST00000487228","GO:0005634(nucleus);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016787(hydrolase activity);GO:0005765(lysosomal membrane);GO:0006629(lipid metabolic process);GO:0008152(metabolic process);GO:0016042(lipid catabolic process);GO:0005783(endoplasmic reticulum);GO:0005739(mitochondrion);GO:0005764(lysosome);GO:0031966(mitochondrial membrane);GO:0043231(intracellular membrane-bounded organelle);GO:0031965(nuclear membrane);GO:0031090(organelle membrane);GO:0032502(developmental process);GO:0004622(lysophospholipase activity);GO:0004622(lysophospholipase activity)","00564(Glycerophospholipid metabolism);00564(Glycerophospholipid metabolism)","K14676","EC:3.1.1.5","patatin like phospholipase domain containing 7 [Source:HGNC Symbol;Acc:HGNC:24768]",{"v":0.277533559342422,"d":"0.28"},{"v":0.127649537289495,"d":"0.13"},{"v":2.17418382577452,"d":"2.17"},{"v":1.12047392441377,"d":"1.12"},{"v":0.0947666073625538,"d":"0.09"},{"v":0.833461713325231,"d":"0.83"},"up","no"]
["ENSG00000133063","CHIT1","ENST00000503786;ENST00000367229;ENST00000506427;ENST00000460619;ENST00000513472;ENST00000479483;ENST00000484834","GO:0016787(hydrolase activity);GO:0005576(extracellular region);GO:0005975(carbohydrate metabolic process);GO:0008152(metabolic process);GO:0004553(hydrolase activity, hydrolyzing O-glycosyl compounds);GO:0016798(hydrolase activity, acting on glycosyl bonds);GO:0006955(immune response);GO:0005615(extracellular space);GO:0008061(chitin binding);GO:0005764(lysosome);GO:0043312(neutrophil degranulation);GO:0035580(specific granule lumen);GO:1904724(tertiary granule lumen);GO:0044245(polysaccharide digestion);GO:0004568(chitinase activity);GO:0008843(endochitinase activity);GO:0000272(polysaccharide catabolic process);GO:0006030(chitin metabolic process);GO:0006032(chitin catabolic process);GO:0009617(response to bacterium);GO:0009617(response to bacterium)","00520(Amino sugar and nucleotide sugar metabolism);00520(Amino sugar and nucleotide sugar metabolism)","K01183","EC:3.2.1.14","chitinase 1 [Source:HGNC Symbol;Acc:HGNC:1936]",{"v":0.0871974063389392,"d":"0.09"},{"v":0.209789344890039,"d":"0.21"},{"v":0.415642683781885,"d":"0.42"},{"v":-1.26658427770388,"d":"-1.27"},{"v":0.0948640597836115,"d":"0.09"},{"v":0.833461713325231,"d":"0.83"},"down","no"]
["MSTRG.7900","ADGRE5","ENST00000242786;ENST00000357355;ENST00000587535;ENST00000587606;ENST00000358600;ENST00000591565;ENST00000587728;ENST00000591080;ENST00000590567;ENST00000586849;ENST00000592341;ENST00000591737;ENST00000586517;ENST00000587319;ENST00000592261;ENST00000593028","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0004930(G-protein coupled receptor activity);GO:0007186(G-protein coupled receptor signaling pathway);GO:0005509(calcium ion binding);GO:0007155(cell adhesion);GO:0005886(plasma membrane);GO:0004871(signal transducer activity);GO:0007165(signal transduction);GO:0005576(extracellular region);GO:0004888(transmembrane signaling receptor activity);GO:0007166(cell surface receptor signaling pathway);GO:0005615(extracellular space);GO:0005925(focal adhesion);GO:0005515(protein binding);GO:0070062(extracellular exosome);GO:0005887(integral component of plasma membrane);GO:0043312(neutrophil degranulation);GO:0006954(inflammatory response);GO:0006955(immune response);GO:0007267(cell-cell signaling);GO:0030667(secretory granule membrane);GO:0006928(movement of cell or subcellular component);GO:0006928(movement of cell or subcellular component)","NA","NA","NA","adhesion G protein-coupled receptor E5 [Source:HGNC Symbol;Acc:HGNC:1711]",{"v":60.552644918246,"d":"60.55"},{"v":132.593398361947,"d":"132.59"},{"v":0.456679183626868,"d":"0.46"},{"v":-1.13074706466908,"d":"-1.13"},{"v":0.0949177099755032,"d":"0.09"},{"v":0.833461713325231,"d":"0.83"},"down","no"]
["ENSG00000213923","CSNK1E","ENST00000396832;ENST00000403904;ENST00000405675;ENST00000442216;ENST00000495232;ENST00000366216;ENST00000430335;ENST00000498529;ENST00000494610;ENST00000612795;ENST00000431611;ENST00000451964;ENST00000413574","GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0005515(protein binding);GO:0048511(rhythmic process);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0008360(regulation of cell shape);GO:0000086(G2/M transition of mitotic cell cycle);GO:0010389(regulation of G2/M transition of mitotic cell cycle);GO:0097711(ciliary basal body docking);GO:0007165(signal transduction);GO:0032922(circadian regulation of gene expression);GO:0006364(rRNA processing);GO:1903827(regulation of cellular protein localization);GO:0016055(Wnt signaling pathway);GO:0042752(regulation of circadian rhythm);GO:0006281(DNA repair);GO:0006897(endocytosis);GO:0032436(positive regulation of proteasomal ubiquitin-dependent protein catabolic process);GO:0018105(peptidyl-serine phosphorylation);GO:0032091(negative regulation of protein binding);GO:1905426(positive regulation of Wnt-mediated midbrain dopaminergic neuron differentiation);GO:2000052(positive regulation of non-canonical Wnt signaling pathway);GO:0048512(circadian behavior);GO:1902004(positive regulation of amyloid-beta formation);GO:1990090(cellular response to nerve growth factor stimulus);GO:0030426(growth cone);GO:0043005(neuron projection);GO:0043025(neuronal cell body);GO:0043025(neuronal cell body)","04310(Wnt signaling pathway);04340(Hedgehog signaling pathway);04390(Hippo signaling pathway);04392(Hippo signaling pathway - multiple species);04068(FoxO signaling pathway);04710(Circadian rhythm);04710(Circadian rhythm)","K08960","EC:2.7.11.1","casein kinase 1 epsilon [Source:HGNC Symbol;Acc:HGNC:2453]",{"v":2.79372293467819,"d":"2.79"},{"v":1.31341098879283,"d":"1.31"},{"v":2.12707443330129,"d":"2.13"},{"v":1.0888705188067,"d":"1.09"},{"v":0.0949938701564689,"d":"0.09"},{"v":0.833461713325231,"d":"0.83"},"up","no"]
["MSTRG.15402","TMEM164","ENST00000288381;MSTRG.15402.4;ENST00000464177;ENST00000471255;ENST00000372073;ENST00000372072;ENST00000372068;ENST00000461715","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016021(integral component of membrane)","NA","NA","NA","transmembrane protein 164 [Source:HGNC Symbol;Acc:HGNC:26217]",{"v":5.19672951116512,"d":"5.20"},{"v":11.3885025069117,"d":"11.39"},{"v":0.456313681979805,"d":"0.46"},{"v":-1.13190218309703,"d":"-1.13"},{"v":0.0950293084533751,"d":"0.10"},{"v":0.833461713325231,"d":"0.83"},"down","no"]
["ENSG00000158321","AUTS2","ENST00000611706;ENST00000406775;ENST00000416482;ENST00000476695;ENST00000481994;ENST00000449547;ENST00000615871;ENST00000342771;ENST00000483297;ENST00000418686;ENST00000465899;ENST00000498384;ENST00000403018;ENST00000464768;ENST00000489774","GO:0003674(molecular_function);GO:0008150(biological_process);GO:0005575(cellular_component);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0003682(chromatin binding);GO:0051571(positive regulation of histone H3-K4 methylation);GO:2000620(positive regulation of histone H4-K16 acetylation);GO:0060013(righting reflex);GO:0098582(innate vocalization behavior);GO:0005634(nucleus);GO:0005634(nucleus)","NA","NA","NA","AUTS2, activator of transcription and developmental regulator [Source:HGNC Symbol;Acc:HGNC:14262]",{"v":1.05257222629559,"d":"1.05"},{"v":0.491819247600768,"d":"0.49"},{"v":2.14016070218954,"d":"2.14"},{"v":1.09771913099429,"d":"1.10"},{"v":0.095269734624567,"d":"0.10"},{"v":0.833908487596854,"d":"0.83"},"up","no"]
["ENSG00000158714","SLAMF8","ENST00000289707;ENST00000471286","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016021(integral component of membrane)","NA","NA","NA","SLAM family member 8 [Source:HGNC Symbol;Acc:HGNC:21391]",{"v":1.643676,"d":"1.64"},{"v":0.758957544726302,"d":"0.76"},{"v":2.16570216795559,"d":"2.17"},{"v":1.11483485404621,"d":"1.11"},{"v":0.0952716877151287,"d":"0.10"},{"v":0.833908487596854,"d":"0.83"},"up","no"]
["MSTRG.6917","HEXIM2","ENST00000585340;ENST00000589230;ENST00000592695;ENST00000591070;ENST00000586681;ENST00000307275;ENST00000593138","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016607(nuclear speck);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0005515(protein binding);GO:0004861(cyclin-dependent protein serine/threonine kinase inhibitor activity);GO:0042802(identical protein binding);GO:0017069(snRNA binding);GO:0097322(7SK snRNA binding);GO:0045736(negative regulation of cyclin-dependent protein serine/threonine kinase activity);GO:0045892(negative regulation of transcription, DNA-templated);GO:0071901(negative regulation of protein serine/threonine kinase activity);GO:0071901(negative regulation of protein serine/threonine kinase activity)","NA","NA","NA","hexamethylene bisacetamide inducible 2 [Source:HGNC Symbol;Acc:HGNC:28591]",{"v":0.783665480372915,"d":"0.78"},{"v":1.76023427772326,"d":"1.76"},{"v":0.445205215175409,"d":"0.45"},{"v":-1.16745760224426,"d":"-1.17"},{"v":0.0952903415545313,"d":"0.10"},{"v":0.833908487596854,"d":"0.83"},"down","no"]
["ENSG00000180316","PNPLA1","ENST00000636260;ENST00000388715","GO:0005737(cytoplasm);GO:0016787(hydrolase activity);GO:0006629(lipid metabolic process);GO:0008152(metabolic process);GO:0016042(lipid catabolic process);GO:0016020(membrane);GO:0004806(triglyceride lipase activity);GO:0019433(triglyceride catabolic process);GO:0055088(lipid homeostasis);GO:0005811(lipid particle);GO:0005811(lipid particle)","NA","NA","NA","patatin like phospholipase domain containing 1 [Source:HGNC Symbol;Acc:HGNC:21246]",{"v":0.683367727752142,"d":"0.68"},{"v":1.53484360547133,"d":"1.53"},{"v":0.445236065300796,"d":"0.45"},{"v":-1.16735763535391,"d":"-1.17"},{"v":0.0953572485817031,"d":"0.10"},{"v":0.833908487596854,"d":"0.83"},"down","no"]
["ENSG00000158089","GALNT14","ENST00000349752;ENST00000486564;ENST00000424136;ENST00000455477;ENST00000461193;ENST00000490212;ENST00000324589;ENST00000475320;ENST00000464038;ENST00000496397;ENST00000481023","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0046872(metal ion binding);GO:0016740(transferase activity);GO:0030246(carbohydrate binding);GO:0016757(transferase activity, transferring glycosyl groups);GO:0005794(Golgi apparatus);GO:0000139(Golgi membrane);GO:0006486(protein glycosylation);GO:0016266(O-glycan processing);GO:0004653(polypeptide N-acetylgalactosaminyltransferase activity);GO:0004653(polypeptide N-acetylgalactosaminyltransferase activity)","00512(Mucin type O-glycan biosynthesis);00512(Mucin type O-glycan biosynthesis)","K00710","EC:2.4.1.41","polypeptide N-acetylgalactosaminyltransferase 14 [Source:HGNC Symbol;Acc:HGNC:22946]",{"v":0.244985718414714,"d":"0.24"},{"v":0.547061174293847,"d":"0.55"},{"v":0.447821431910141,"d":"0.45"},{"v":-1.15900452031323,"d":"-1.16"},{"v":0.095437299111069,"d":"0.10"},{"v":0.834002870751446,"d":"0.83"},"down","no"]
["ENSG00000188706","ZDHHC9","ENST00000357166;ENST00000406492;ENST00000491039;ENST00000371064","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005794(Golgi apparatus);GO:0005829(cytosol);GO:0016740(transferase activity);GO:0016746(transferase activity, transferring acyl groups);GO:0019706(protein-cysteine S-palmitoyltransferase activity);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005515(protein binding);GO:0000139(Golgi membrane);GO:0016409(palmitoyltransferase activity);GO:0018345(protein palmitoylation);GO:0018230(peptidyl-L-cysteine S-palmitoylation);GO:0002178(palmitoyltransferase complex);GO:0031228(intrinsic component of Golgi membrane);GO:0043849(Ras palmitoyltransferase activity);GO:0043849(Ras palmitoyltransferase activity)","NA","NA","NA","zinc finger DHHC-type containing 9 [Source:HGNC Symbol;Acc:HGNC:18475]",{"v":0.779466206370399,"d":"0.78"},{"v":0.360357449170322,"d":"0.36"},{"v":2.16303619687902,"d":"2.16"},{"v":1.11305780798178,"d":"1.11"},{"v":0.0956001880457385,"d":"0.10"},{"v":0.834354534925672,"d":"0.83"},"up","no"]
["ENSG00000122378","FAM213A","ENST00000372187;ENST00000372188;ENST00000372181;ENST00000615554;ENST00000606162;ENST00000372185","GO:0005737(cytoplasm);GO:0055114(oxidation-reduction process);GO:0005576(extracellular region);GO:0098869(cellular oxidant detoxification);GO:0070062(extracellular exosome);GO:0016209(antioxidant activity);GO:0045670(regulation of osteoclast differentiation);GO:0045670(regulation of osteoclast differentiation)","NA","NA","NA","family with sequence similarity 213 member A [Source:HGNC Symbol;Acc:HGNC:28651]",{"v":0.330759742331288,"d":"0.33"},{"v":0.14763058696319,"d":"0.15"},{"v":2.24045537672867,"d":"2.24"},{"v":1.16379199254114,"d":"1.16"},{"v":0.0956161151135549,"d":"0.10"},{"v":0.834354534925672,"d":"0.83"},"up","no"]
["MSTRG.3409","NFE2","ENST00000553070;ENST00000435572;ENST00000312156;ENST00000540264;ENST00000553198","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0005515(protein binding);GO:0005654(nucleoplasm);GO:0047485(protein N-terminus binding);GO:0003713(transcription coactivator activity);GO:0007275(multicellular organism development);GO:0045893(positive regulation of transcription, DNA-templated);GO:0016605(PML body);GO:0000976(transcription regulatory region sequence-specific DNA binding);GO:0006337(nucleosome disassembly);GO:0045652(regulation of megakaryocyte differentiation);GO:0007596(blood coagulation);GO:0043565(sequence-specific DNA binding);GO:0032993(protein-DNA complex);GO:0008015(blood circulation);GO:0007599(hemostasis);GO:0050699(WW domain binding);GO:0050699(WW domain binding)","NA","NA","NA","nuclear factor, erythroid 2 [Source:HGNC Symbol;Acc:HGNC:7780]",{"v":16.1940722494937,"d":"16.19"},{"v":35.427674563791,"d":"35.43"},{"v":0.457102320400248,"d":"0.46"},{"v":-1.12941095233694,"d":"-1.13"},{"v":0.0957190667375172,"d":"0.10"},{"v":0.834648082297742,"d":"0.83"},"down","no"]
["MSTRG.2476","TMEM223","ENST00000307366;ENST00000525631;ENST00000528367","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005739(mitochondrion);GO:0007399(nervous system development);GO:0007399(nervous system development)","NA","NA","NA","transmembrane protein 223 [Source:HGNC Symbol;Acc:HGNC:28464]",{"v":0.644648253947368,"d":"0.64"},{"v":1.44295468333333,"d":"1.44"},{"v":0.446755716858816,"d":"0.45"},{"v":-1.16244190421916,"d":"-1.16"},{"v":0.0958631679172773,"d":"0.10"},{"v":0.83529975981176,"d":"0.84"},"down","no"]
["ENSG00000135127","BICDL1","ENST00000397558;ENST00000548673;ENST00000546861;ENST00000546460;ENST00000550197;ENST00000546420;ENST00000547841;ENST00000546502;ENST00000550245","GO:0006810(transport);GO:0005737(cytoplasm);GO:0005856(cytoskeleton);GO:0007399(nervous system development);GO:0005813(centrosome);GO:0005815(microtubule organizing center);GO:0031175(neuron projection development);GO:0017137(Rab GTPase binding);GO:0034452(dynactin binding);GO:0055107(Golgi to secretory granule transport);GO:0055107(Golgi to secretory granule transport)","NA","NA","NA","BICD family like cargo adaptor 1 [Source:HGNC Symbol;Acc:HGNC:28095]",{"v":2.62089950437637,"d":"2.62"},{"v":1.23671314186725,"d":"1.24"},{"v":2.11924610133859,"d":"2.12"},{"v":1.08355113304495,"d":"1.08"},{"v":0.0961942572435135,"d":"0.10"},{"v":0.836941761251382,"d":"0.84"},"up","no"]
["ENSG00000187695","AC112484.1","ENST00000637488;ENST00000508239;ENST00000511204","NA","NA","NA","NA","Uncharacterized protein FLJ43738  [Source:UniProtKB/Swiss-Prot;Acc:Q6ZUG5]",{"v":0.335876906390977,"d":"0.34"},{"v":0.770081067669173,"d":"0.77"},{"v":0.436157854662738,"d":"0.44"},{"v":-1.19707772382346,"d":"-1.20"},{"v":0.0962601178652354,"d":"0.10"},{"v":0.836941761251382,"d":"0.84"},"down","no"]
["MSTRG.4074","DOCK9","MSTRG.4074.1","NA","NA","NA","NA",null,{"v":2.756669,"d":"2.76"},{"v":1.250684,"d":"1.25"},{"v":2.20412910055618,"d":"2.20"},{"v":1.14020872811844,"d":"1.14"},{"v":0.0962601178652354,"d":"0.10"},{"v":0.836941761251382,"d":"0.84"},"up","no"]
["ENSG00000164815","ORC5","ENST00000447452;ENST00000485726;ENST00000422497;ENST00000477223;ENST00000297431","GO:0005634(nucleus);GO:0006260(DNA replication);GO:0000808(origin recognition complex);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0005829(cytosol);GO:0005515(protein binding);GO:0003674(molecular_function);GO:0005654(nucleoplasm);GO:0000784(nuclear chromosome, telomeric region);GO:0000082(G1/S transition of mitotic cell cycle);GO:0003688(DNA replication origin binding);GO:0006270(DNA replication initiation);GO:0005664(nuclear origin of replication recognition complex);GO:0005664(nuclear origin of replication recognition complex)","04110(Cell cycle);04110(Cell cycle)","K02607","NA","origin recognition complex subunit 5 [Source:HGNC Symbol;Acc:HGNC:8491]",{"v":0.604751589957035,"d":"0.60"},{"v":1.34163737003222,"d":"1.34"},{"v":0.450756369392507,"d":"0.45"},{"v":-1.14958021714864,"d":"-1.15"},{"v":0.0964423678178187,"d":"0.10"},{"v":0.837921351560009,"d":"0.84"},"down","no"]
["MSTRG.10257","ZNF280B","ENST00000626650","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding)","NA","NA","NA","zinc finger protein 280B [Source:HGNC Symbol;Acc:HGNC:23022]",{"v":0.265767090686703,"d":"0.27"},{"v":0.118570549012756,"d":"0.12"},{"v":2.24142582538022,"d":"2.24"},{"v":1.16441675764123,"d":"1.16"},{"v":0.0966186163391148,"d":"0.10"},{"v":0.838317833989559,"d":"0.84"},"up","no"]
["MSTRG.1602","PLXDC2","MSTRG.1602.3;ENST00000377252;ENST00000377242;ENST00000377238","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005515(protein binding);GO:0070062(extracellular exosome);GO:0070062(extracellular exosome)","NA","NA","NA","plexin domain containing 2 [Source:HGNC Symbol;Acc:HGNC:21013]",{"v":4.04824798114245,"d":"4.05"},{"v":8.83620536151489,"d":"8.84"},{"v":0.458143265747777,"d":"0.46"},{"v":-1.12612928157889,"d":"-1.13"},{"v":0.0966272341452838,"d":"0.10"},{"v":0.838317833989559,"d":"0.84"},"down","no"]
["MSTRG.1596","VIM-AS1","ENST00000605833;ENST00000437232","NA","NA","NA","NA","VIM antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:44879]",{"v":2.02370897289157,"d":"2.02"},{"v":4.44654263704819,"d":"4.45"},{"v":0.455119659942134,"d":"0.46"},{"v":-1.13568218669947,"d":"-1.14"},{"v":0.0969363582231726,"d":"0.10"},{"v":0.840394258980162,"d":"0.84"},"down","no"]
["MSTRG.6329","CXCL16","ENST00000293778;ENST00000574412;ENST00000576153;ENST00000575168;ENST00000573123","GO:0005615(extracellular space);GO:0030335(positive regulation of cell migration);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005886(plasma membrane);GO:0005576(extracellular region);GO:0006935(chemotaxis);GO:0005044(scavenger receptor activity);GO:0005125(cytokine activity);GO:0008009(chemokine activity);GO:0006898(receptor-mediated endocytosis);GO:0030307(positive regulation of cell growth);GO:0005041(low-density lipoprotein receptor activity);GO:0034097(response to cytokine);GO:0034341(response to interferon-gamma);GO:0034612(response to tumor necrosis factor);GO:0048247(lymphocyte chemotaxis);GO:0010818(T cell chemotaxis);GO:0042379(chemokine receptor binding);GO:0071222(cellular response to lipopolysaccharide);GO:0071222(cellular response to lipopolysaccharide)","04060(Cytokine-cytokine receptor interaction);04062(Chemokine signaling pathway);04062(Chemokine signaling pathway)","K10035","NA","C-X-C motif chemokine ligand 16 [Source:HGNC Symbol;Acc:HGNC:16642]",{"v":7.27265435289907,"d":"7.27"},{"v":15.8656344889048,"d":"15.87"},{"v":0.458390388230928,"d":"0.46"},{"v":-1.12535130165851,"d":"-1.13"},{"v":0.0972413457215656,"d":"0.10"},{"v":0.842431859841074,"d":"0.84"},"down","no"]
["MSTRG.12289","IRF1","ENST00000245414;ENST00000613424;ENST00000472045;ENST00000405885;ENST00000493208;ENST00000439555;ENST00000463784;ENST00000476613;ENST00000459982;ENST00000458069;ENST00000437654","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0006915(apoptotic process);GO:0005515(protein binding);GO:0008285(negative regulation of cell proliferation);GO:0045893(positive regulation of transcription, DNA-templated);GO:0002376(immune system process);GO:0045087(innate immune response);GO:0000975(regulatory region DNA binding);GO:0051607(defense response to virus);GO:0050776(regulation of immune response);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0007050(cell cycle arrest);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0071260(cellular response to mechanical stimulus);GO:0045892(negative regulation of transcription, DNA-templated);GO:0000790(nuclear chromatin);GO:0006366(transcription from RNA polymerase II promoter);GO:0051726(regulation of cell cycle);GO:0032728(positive regulation of interferon-beta production);GO:0060333(interferon-gamma-mediated signaling pathway);GO:0001077(transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0060337(type I interferon signaling pathway);GO:0007596(blood coagulation);GO:0035458(cellular response to interferon-beta);GO:0045088(regulation of innate immune response);GO:0043565(sequence-specific DNA binding);GO:0002819(regulation of adaptive immune response);GO:0010468(regulation of gene expression);GO:0032481(positive regulation of type I interferon production);GO:0034124(regulation of MyD88-dependent toll-like receptor signaling pathway);GO:0043374(CD8-positive, alpha-beta T cell differentiation);GO:0045084(positive regulation of interleukin-12 biosynthetic process);GO:0045590(negative regulation of regulatory T cell differentiation);GO:2000564(regulation of CD8-positive, alpha-beta T cell proliferation);GO:2000564(regulation of CD8-positive, alpha-beta T cell proliferation)","04917(Prolactin signaling pathway);05133(Pertussis);05160(Hepatitis C);05165(Human papillomavirus infection);05165(Human papillomavirus infection)","K09444","NA","interferon regulatory factor 1 [Source:HGNC Symbol;Acc:HGNC:6116]",{"v":14.1752073905629,"d":"14.18"},{"v":30.8617393756892,"d":"30.86"},{"v":0.459313301107363,"d":"0.46"},{"v":-1.12244953217811,"d":"-1.12"},{"v":0.0975782476441096,"d":"0.10"},{"v":0.844742816772371,"d":"0.84"},"down","no"]
["ENSG00000091129","NRCAM","ENST00000379028;ENST00000522550;ENST00000379024;ENST00000351718","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0007155(cell adhesion);GO:0005886(plasma membrane);GO:0042995(cell projection);GO:0005576(extracellular region);GO:0005887(integral component of plasma membrane);GO:0005515(protein binding);GO:0030424(axon);GO:0007409(axonogenesis);GO:0043005(neuron projection);GO:0045162(clustering of voltage-gated sodium channels);GO:0001525(angiogenesis);GO:0016337(single organismal cell-cell adhesion);GO:0043194(axon initial segment);GO:0001764(neuron migration);GO:0007416(synapse assembly);GO:0009897(external side of plasma membrane);GO:0034113(heterotypic cell-cell adhesion);GO:0007417(central nervous system development);GO:0030516(regulation of axon extension);GO:0045666(positive regulation of neuron differentiation);GO:0007413(axonal fasciculation);GO:0030506(ankyrin binding);GO:0086080(protein binding involved in heterotypic cell-cell adhesion);GO:0007411(axon guidance);GO:0008104(protein localization);GO:0010975(regulation of neuron projection development);GO:0019227(neuronal action potential propagation);GO:0031290(retinal ganglion cell axon guidance);GO:0045202(synapse);GO:0045202(synapse)","04514(Cell adhesion molecules (CAMs));04514(Cell adhesion molecules (CAMs))","K06756","NA","neuronal cell adhesion molecule [Source:HGNC Symbol;Acc:HGNC:7994]",{"v":0.419788890150128,"d":"0.42"},{"v":0.196354240205053,"d":"0.20"},{"v":2.13791609344286,"d":"2.14"},{"v":1.09620523287632,"d":"1.10"},{"v":0.0977672310494906,"d":"0.10"},{"v":0.845348374089499,"d":"0.85"},"up","no"]
["MSTRG.1466","EGLN1","ENST00000476717;ENST00000366641;MSTRG.1466.1","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0005829(cytosol);GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0005506(iron ion binding);GO:0016705(oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen);GO:0031418(L-ascorbic acid binding);GO:0005515(protein binding);GO:0051213(dioxygenase activity);GO:0061418(regulation of transcription from RNA polymerase II promoter in response to hypoxia);GO:0019899(enzyme binding);GO:0045765(regulation of angiogenesis);GO:0001666(response to hypoxia);GO:0030821(negative regulation of cAMP catabolic process);GO:0051344(negative regulation of cyclic-nucleotide phosphodiesterase activity);GO:0032364(oxygen homeostasis);GO:0043433(negative regulation of sequence-specific DNA binding transcription factor activity);GO:0016706(oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors);GO:0031545(peptidyl-proline 4-dioxygenase activity);GO:0018401(peptidyl-proline hydroxylation to 4-hydroxy-L-proline);GO:0031543(peptidyl-proline dioxygenase activity);GO:0006879(cellular iron ion homeostasis);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0055008(cardiac muscle tissue morphogenesis);GO:0060347(heart trabecula formation);GO:0060412(ventricular septum morphogenesis);GO:0060711(labyrinthine layer development);GO:0071731(response to nitric oxide);GO:1901214(regulation of neuron death);GO:1901214(regulation of neuron death)","04066(HIF-1 signaling pathway);05200(Pathways in cancer);05211(Renal cell carcinoma);05211(Renal cell carcinoma)","K09592","EC:1.14.11.29","egl-9 family hypoxia inducible factor 1 [Source:HGNC Symbol;Acc:HGNC:1232]",{"v":2.30300227829495,"d":"2.30"},{"v":5.02065006430671,"d":"5.02"},{"v":0.458705994004178,"d":"0.46"},{"v":-1.12435833535586,"d":"-1.12"},{"v":0.0977885970027132,"d":"0.10"},{"v":0.845348374089499,"d":"0.85"},"down","no"]
["MSTRG.8857","TMSB10","ENST00000233143;MSTRG.8857.1","GO:0005737(cytoplasm);GO:0007015(actin filament organization);GO:0003779(actin binding);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0003785(actin monomer binding)","NA","NA","NA","thymosin beta 10 [Source:HGNC Symbol;Acc:HGNC:11879]",{"v":105.454021406857,"d":"105.45"},{"v":229.282021578286,"d":"229.28"},{"v":0.459931488221159,"d":"0.46"},{"v":-1.120509122772,"d":"-1.12"},{"v":0.0979850573022506,"d":"0.10"},{"v":0.845943915032877,"d":"0.85"},"down","no"]
["ENSG00000253797","UTP14C","ENST00000521776","GO:0005634(nucleus);GO:0005730(nucleolus);GO:0005829(cytosol);GO:0005515(protein binding);GO:0007275(multicellular organism development);GO:0051321(meiotic cell cycle);GO:0030154(cell differentiation);GO:0042254(ribosome biogenesis);GO:0007283(spermatogenesis);GO:0006364(rRNA processing);GO:0032040(small-subunit processome);GO:0030490(maturation of SSU-rRNA)","03008(Ribosome biogenesis in eukaryotes)","K14567","NA","UTP14C, small subunit processome component [Source:HGNC Symbol;Acc:HGNC:20321]",{"v":0.907967,"d":"0.91"},{"v":0.426388,"d":"0.43"},{"v":2.12943844573487,"d":"2.13"},{"v":1.09047302746208,"d":"1.09"},{"v":0.0980325283582487,"d":"0.10"},{"v":0.845943915032877,"d":"0.85"},"up","no"]
["ENSG00000060558","GNA15","ENST00000262958;ENST00000592455;ENST00000586082","GO:0005525(GTP binding);GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0007186(G-protein coupled receptor signaling pathway);GO:0007165(signal transduction);GO:0003924(GTPase activity);GO:0004871(signal transducer activity);GO:0001664(G-protein coupled receptor binding);GO:0019001(guanyl nucleotide binding);GO:0031683(G-protein beta/gamma-subunit complex binding);GO:0005886(plasma membrane);GO:0007188(adenylate cyclase-modulating G-protein coupled receptor signaling pathway);GO:0005834(heterotrimeric G-protein complex);GO:0030168(platelet activation);GO:0007204(positive regulation of cytosolic calcium ion concentration);GO:0060158(phospholipase C-activating dopamine receptor signaling pathway);GO:0007202(activation of phospholipase C activity);GO:0007207(phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway);GO:0007200(phospholipase C-activating G-protein coupled receptor signaling pathway);GO:0007200(phospholipase C-activating G-protein coupled receptor signaling pathway)","04020(Calcium signaling pathway);04926(Relaxin signaling pathway);05146(Amoebiasis);05142(Chagas disease (American trypanosomiasis));05142(Chagas disease (American trypanosomiasis))","K04637","NA","G protein subunit alpha 15 [Source:HGNC Symbol;Acc:HGNC:4383]",{"v":2.28586413356295,"d":"2.29"},{"v":5.01786821469575,"d":"5.02"},{"v":0.455544871997311,"d":"0.46"},{"v":-1.13433492577869,"d":"-1.13"},{"v":0.0980682366206524,"d":"0.10"},{"v":0.845943915032877,"d":"0.85"},"down","no"]
["MSTRG.7383","EMILIN2","MSTRG.7383.2;ENST00000254528;ENST00000308080;ENST00000583776","GO:0007155(cell adhesion);GO:0005576(extracellular region);GO:0005581(collagen trimer);GO:0005578(proteinaceous extracellular matrix);GO:0005515(protein binding);GO:0008150(biological_process);GO:0031012(extracellular matrix);GO:0030023(extracellular matrix constituent conferring elasticity);GO:0005615(extracellular space);GO:0005615(extracellular space)","NA","NA","NA","elastin microfibril interfacer 2 [Source:HGNC Symbol;Acc:HGNC:19881]",{"v":4.60659876925342,"d":"4.61"},{"v":10.0228039687822,"d":"10.02"},{"v":0.459611779657817,"d":"0.46"},{"v":-1.12151232075857,"d":"-1.12"},{"v":0.0981595682120855,"d":"0.10"},{"v":0.846125640951993,"d":"0.85"},"down","no"]
["MSTRG.14554","LINC00861","ENST00000500989;ENST00000517869;ENST00000518964;ENST00000522865","NA","NA","NA","NA","long intergenic non-protein coding RNA 861 [Source:HGNC Symbol;Acc:HGNC:45133]",{"v":12.1452789234801,"d":"12.15"},{"v":5.79324724685535,"d":"5.79"},{"v":2.09645444186293,"d":"2.10"},{"v":1.06795147926011,"d":"1.07"},{"v":0.0983465057481588,"d":"0.10"},{"v":0.846377503171386,"d":"0.85"},"up","no"]
["MSTRG.342","LAPTM5","ENST00000294507;ENST00000476492;ENST00000464569","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005887(integral component of plasma membrane);GO:0005765(lysosomal membrane);GO:0005515(protein binding);GO:0005764(lysosome);GO:1990830(cellular response to leukemia inhibitory factor);GO:1990830(cellular response to leukemia inhibitory factor)","04142(Lysosome);04142(Lysosome)","K12387","NA","lysosomal protein transmembrane 5 [Source:HGNC Symbol;Acc:HGNC:29612]",{"v":92.0857206844838,"d":"92.09"},{"v":199.974213125229,"d":"199.97"},{"v":0.460487976151292,"d":"0.46"},{"v":-1.11876460843693,"d":"-1.12"},{"v":0.098397524048625,"d":"0.10"},{"v":0.846377503171386,"d":"0.85"},"down","no"]
["ENSG00000234585","CCT6P3","ENST00000419314;ENST00000452026;ENST00000426828","NA","NA","NA","NA","chaperonin containing TCP1 subunit 6 pseudogene 3 [Source:HGNC Symbol;Acc:HGNC:35137]",{"v":0.607146416326531,"d":"0.61"},{"v":0.275889352040816,"d":"0.28"},{"v":2.20068810860344,"d":"2.20"},{"v":1.13795469450022,"d":"1.14"},{"v":0.0983996432851636,"d":"0.10"},{"v":0.846377503171386,"d":"0.85"},"up","no"]
["ENSG00000186814","ZSCAN30","ENST00000589178;ENST00000601405;ENST00000588832;ENST00000588448;ENST00000639929;ENST00000590777;ENST00000420878;ENST00000333206;ENST00000592278","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding)","NA","NA","NA","zinc finger and SCAN domain containing 30 [Source:HGNC Symbol;Acc:HGNC:33517]",{"v":0.903575053318825,"d":"0.90"},{"v":0.423972189819853,"d":"0.42"},{"v":2.13121302532309,"d":"2.13"},{"v":1.09167480486022,"d":"1.09"},{"v":0.0986240823567694,"d":"0.10"},{"v":0.847702498030134,"d":"0.85"},"up","no"]
["MSTRG.12708","TDP2","ENST00000378198;ENST00000478507;ENST00000480495;ENST00000341060;ENST00000478285","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0005654(nucleoplasm);GO:0016787(hydrolase activity);GO:0090305(nucleic acid phosphodiester bond hydrolysis);GO:0016235(aggresome);GO:0006281(DNA repair);GO:0006974(cellular response to DNA damage stimulus);GO:0016604(nuclear body);GO:0000287(magnesium ion binding);GO:0004518(nuclease activity);GO:0005730(nucleolus);GO:1903507(negative regulation of nucleic acid-templated transcription);GO:0005515(protein binding);GO:0048666(neuron development);GO:0007166(cell surface receptor signaling pathway);GO:0003714(transcription corepressor activity);GO:0016605(PML body);GO:0003697(single-stranded DNA binding);GO:0006302(double-strand break repair);GO:0030145(manganese ion binding);GO:0036317(tyrosyl-RNA phosphodiesterase activity);GO:0070260(5'-tyrosyl-DNA phosphodiesterase activity);GO:0070260(5'-tyrosyl-DNA phosphodiesterase activity)","NA","NA","NA","tyrosyl-DNA phosphodiesterase 2 [Source:HGNC Symbol;Acc:HGNC:17768]",{"v":13.2360650077872,"d":"13.24"},{"v":28.7651781609345,"d":"28.77"},{"v":0.460141944323602,"d":"0.46"},{"v":-1.11984912332006,"d":"-1.12"},{"v":0.0987002877535962,"d":"0.10"},{"v":0.847752400234526,"d":"0.85"},"down","no"]
["MSTRG.8385","ZNF649;ZNF577;AC074141.1","ENST00000354957;ENST00000599530;ENST00000301399;ENST00000638827;ENST00000640429;ENST00000639636;ENST00000597882;ENST00000638325;ENST00000638684;ENST00000638348;ENST00000588129;ENST00000595418;ENST00000600738;ENST00000639703;ENST00000640955;ENST00000451628;ENST00000640678","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0005622(intracellular);GO:0005515(protein binding);GO:0005615(extracellular space);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0044212(transcription regulatory region DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding)","NA","NA","NA","zinc finger protein 649 [Source:HGNC Symbol;Acc:HGNC:25741];zinc finger protein 577 [Source:HGNC Symbol;Acc:HGNC:28673]",{"v":0.499137093647091,"d":"0.50"},{"v":0.235435688803513,"d":"0.24"},{"v":2.12005705755025,"d":"2.12"},{"v":1.084103092872,"d":"1.08"},{"v":0.0987759841640713,"d":"0.10"},{"v":0.847797862654131,"d":"0.85"},"up","no"]
["MSTRG.11836","MGST2","ENST00000265498;ENST00000515137;ENST00000515067;ENST00000503816;ENST00000502587;ENST00000506797","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016740(transferase activity);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005886(plasma membrane);GO:0008047(enzyme activator activity);GO:0043085(positive regulation of catalytic activity);GO:0005515(protein binding);GO:0098869(cellular oxidant detoxification);GO:0006691(leukotriene metabolic process);GO:0004364(glutathione transferase activity);GO:0019370(leukotriene biosynthetic process);GO:0043231(intracellular membrane-bounded organelle);GO:0005635(nuclear envelope);GO:0006805(xenobiotic metabolic process);GO:0031090(organelle membrane);GO:0004602(glutathione peroxidase activity);GO:1901687(glutathione derivative biosynthetic process);GO:0006750(glutathione biosynthetic process);GO:0004464(leukotriene-C4 synthase activity);GO:0010243(response to organonitrogen compound);GO:0032496(response to lipopolysaccharide);GO:0005737(cytoplasm);GO:0005737(cytoplasm)","00480(Glutathione metabolism);00980(Metabolism of xenobiotics by cytochrome P450);00982(Drug metabolism - cytochrome P450);00983(Drug metabolism - other enzymes);05200(Pathways in cancer);05204(Chemical carcinogenesis);05225(Hepatocellular carcinoma);05418(Fluid shear stress and atherosclerosis);01524(Platinum drug resistance);01524(Platinum drug resistance)","K00799","EC:2.5.1.18","microsomal glutathione S-transferase 2 [Source:HGNC Symbol;Acc:HGNC:7063]",{"v":0.482574095851666,"d":"0.48"},{"v":1.08390690414833,"d":"1.08"},{"v":0.445217291268058,"d":"0.45"},{"v":-1.1674184699922,"d":"-1.17"},{"v":0.0988631350772037,"d":"0.10"},{"v":0.847831981729388,"d":"0.85"},"down","no"]
["MSTRG.2248","RNF141","ENST00000265981;ENST00000534281;ENST00000528665;ENST00000533412;ENST00000530156","GO:0016020(membrane);GO:0046872(metal ion binding);GO:0004842(ubiquitin-protein transferase activity);GO:0051865(protein autoubiquitination);GO:0003677(DNA binding);GO:0006355(regulation of transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated)","NA","NA","NA","ring finger protein 141 [Source:HGNC Symbol;Acc:HGNC:21159]",{"v":2.43930612659847,"d":"2.44"},{"v":5.30089090869565,"d":"5.30"},{"v":0.460169086407155,"d":"0.46"},{"v":-1.11976402654724,"d":"-1.12"},{"v":0.0990342866049467,"d":"0.10"},{"v":0.847831981729388,"d":"0.85"},"down","no"]
["MSTRG.11300","LXN","ENST00000264265;ENST00000482640","GO:0005737(cytoplasm);GO:0010951(negative regulation of endopeptidase activity);GO:0005515(protein binding);GO:0006954(inflammatory response);GO:0030414(peptidase inhibitor activity);GO:0010466(negative regulation of peptidase activity);GO:0008201(heparin binding);GO:0070062(extracellular exosome);GO:0004857(enzyme inhibitor activity);GO:0008191(metalloendopeptidase inhibitor activity);GO:0050965(detection of temperature stimulus involved in sensory perception of pain);GO:0050965(detection of temperature stimulus involved in sensory perception of pain)","NA","NA","NA","latexin [Source:HGNC Symbol;Acc:HGNC:13347]",{"v":0.789102929521277,"d":"0.79"},{"v":1.7867731356383,"d":"1.79"},{"v":0.441635769971089,"d":"0.44"},{"v":-1.17907106799324,"d":"-1.18"},{"v":0.0990376997833022,"d":"0.10"},{"v":0.847831981729388,"d":"0.85"},"down","no"]
["MSTRG.13841","ZNHIT1","ENST00000305105;ENST00000492315;ENST00000461205;ENST00000485387","GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0005654(nucleoplasm);GO:0005515(protein binding);GO:0031491(nucleosome binding);GO:0042826(histone deacetylase binding);GO:0031063(regulation of histone deacetylation);GO:0043486(histone exchange);GO:0000812(Swr1 complex);GO:0000812(Swr1 complex)","NA","NA","NA","zinc finger HIT-type containing 1 [Source:HGNC Symbol;Acc:HGNC:21688]",{"v":1.49711793920145,"d":"1.50"},{"v":3.26880552014519,"d":"3.27"},{"v":0.458001532968212,"d":"0.46"},{"v":-1.12657566773996,"d":"-1.13"},{"v":0.0990615843126763,"d":"0.10"},{"v":0.847831981729388,"d":"0.85"},"down","no"]
["MSTRG.10769","CMTM6","ENST00000205636;ENST00000495177;ENST00000478886","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005125(cytokine activity);GO:0005615(extracellular space);GO:0006935(chemotaxis);GO:0005886(plasma membrane);GO:0070062(extracellular exosome);GO:0043312(neutrophil degranulation);GO:0035579(specific granule membrane);GO:0035577(azurophil granule membrane);GO:0035577(azurophil granule membrane)","NA","NA","NA","CKLF like MARVEL transmembrane domain containing 6 [Source:HGNC Symbol;Acc:HGNC:19177]",{"v":17.7439910740993,"d":"17.74"},{"v":38.4868226004985,"d":"38.49"},{"v":0.461040685490869,"d":"0.46"},{"v":-1.1170340250008,"d":"-1.12"},{"v":0.0991469756974226,"d":"0.10"},{"v":0.847960143003099,"d":"0.85"},"down","no"]
["MSTRG.6707","SLFN12L","MSTRG.6707.1","NA","NA","NA","NA",null,{"v":6.084098,"d":"6.08"},{"v":2.880852,"d":"2.88"},{"v":2.11190925462328,"d":"2.11"},{"v":1.07854784572023,"d":"1.08"},{"v":0.099273697113196,"d":"0.10"},{"v":0.848441348926264,"d":"0.85"},"up","no"]
["ENSG00000185630","PBX1","ENST00000560641;ENST00000474046;ENST00000559240;ENST00000467023;ENST00000465089;ENST00000468104;ENST00000605467;ENST00000340699;ENST00000498497;ENST00000612123;ENST00000540236;ENST00000367897;ENST00000420696;ENST00000485769","GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0006355(regulation of transcription, DNA-templated);GO:0005737(cytoplasm);GO:0006366(transcription from RNA polymerase II promoter);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0006694(steroid biosynthetic process);GO:0043565(sequence-specific DNA binding);GO:0005515(protein binding);GO:0007275(multicellular organism development);GO:0030154(cell differentiation);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:0001077(transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0046982(protein heterodimerization activity);GO:0001655(urogenital system development);GO:0001658(branching involved in ureteric bud morphogenesis);GO:0008284(positive regulation of cell proliferation);GO:0009887(animal organ morphogenesis);GO:0009952(anterior/posterior pattern specification);GO:0009954(proximal/distal pattern formation);GO:0010971(positive regulation of G2/M transition of mitotic cell cycle);GO:0030278(regulation of ossification);GO:0030325(adrenal gland development);GO:0030326(embryonic limb morphogenesis);GO:0035162(embryonic hemopoiesis);GO:0042127(regulation of cell proliferation);GO:0045665(negative regulation of neuron differentiation);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0048536(spleen development);GO:0048538(thymus development);GO:0048568(embryonic organ development);GO:0048706(embryonic skeletal system development);GO:0005667(transcription factor complex);GO:0007548(sex differentiation);GO:0000977(RNA polymerase II regulatory region sequence-specific DNA binding);GO:0090575(RNA polymerase II transcription factor complex);GO:0035019(somatic stem cell population maintenance);GO:0035019(somatic stem cell population maintenance)","04927(Cortisol synthesis and secretion);05202(Transcriptional misregulation in cancers);05202(Transcriptional misregulation in cancers)","K09355","NA","PBX homeobox 1 [Source:HGNC Symbol;Acc:HGNC:8632]",{"v":0.258168032095628,"d":"0.26"},{"v":0.567675272954021,"d":"0.57"},{"v":0.454781182826926,"d":"0.45"},{"v":-1.13675553283816,"d":"-1.14"},{"v":0.0994028830426663,"d":"0.10"},{"v":0.848942920283537,"d":"0.85"},"down","no"]
["MSTRG.1507","TRIM58","ENST00000366481;MSTRG.1507.1;MSTRG.1507.2","GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0016740(transferase activity);GO:0016567(protein ubiquitination);GO:0005622(intracellular)","NA","NA","NA","tripartite motif containing 58 [Source:HGNC Symbol;Acc:HGNC:24150]",{"v":27.7281658522255,"d":"27.73"},{"v":13.2739707784372,"d":"13.27"},{"v":2.08891267843292,"d":"2.09"},{"v":1.06275218554774,"d":"1.06"},{"v":0.0995953508754576,"d":"0.10"},{"v":0.849451958661787,"d":"0.85"},"up","no"]
["MSTRG.13713","LAT2","ENST00000398475;ENST00000275635;ENST00000344995;ENST00000460943;ENST00000490586;ENST00000488266;ENST00000361082;ENST00000491595;ENST00000470709;ENST00000475494","GO:0042113(B cell activation);GO:0002764(immune response-regulating signaling pathway);GO:0005622(intracellular);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005886(plasma membrane);GO:0002376(immune system process);GO:0002250(adaptive immune response);GO:0038095(Fc-epsilon receptor signaling pathway);GO:0042629(mast cell granule);GO:0070062(extracellular exosome);GO:0005515(protein binding);GO:0043303(mast cell degranulation);GO:0019722(calcium-mediated signaling);GO:0035556(intracellular signal transduction);GO:0045121(membrane raft);GO:0042169(SH2 domain binding);GO:0050853(B cell receptor signaling pathway);GO:0050853(B cell receptor signaling pathway)","NA","NA","NA","linker for activation of T-cells family member 2 [Source:HGNC Symbol;Acc:HGNC:12749]",{"v":13.1035687843784,"d":"13.10"},{"v":28.3990476070407,"d":"28.40"},{"v":0.461408740380778,"d":"0.46"},{"v":-1.11588276190121,"d":"-1.12"},{"v":0.0996631149936046,"d":"0.10"},{"v":0.849451958661787,"d":"0.85"},"down","no"]
["ENSG00000168005","C11orf84","ENST00000294244;ENST00000540893;ENST00000535820","NA","NA","NA","NA","chromosome 11 open reading frame 84 [Source:HGNC Symbol;Acc:HGNC:25115]",{"v":2.48890962166013,"d":"2.49"},{"v":1.17204876166726,"d":"1.17"},{"v":2.12355467030195,"d":"2.12"},{"v":1.08648125093077,"d":"1.09"},{"v":0.0998460236658038,"d":"0.10"},{"v":0.849451958661787,"d":"0.85"},"up","no"]
["ENSG00000095951","HIVEP1","ENST00000379388;ENST00000484210;ENST00000627968;ENST00000491710;ENST00000442081;ENST00000487103","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0005654(nucleoplasm);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0005739(mitochondrion);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0016604(nuclear body);GO:0007165(signal transduction);GO:0007275(multicellular organism development);GO:0043565(sequence-specific DNA binding);GO:0044212(transcription regulatory region DNA binding);GO:0000980(RNA polymerase II distal enhancer sequence-specific DNA binding);GO:0001206(transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0006366(transcription from RNA polymerase II promoter);GO:0006366(transcription from RNA polymerase II promoter)","NA","NA","NA","human immunodeficiency virus type I enhancer binding protein 1 [Source:HGNC Symbol;Acc:HGNC:4920]",{"v":0.309680605155296,"d":"0.31"},{"v":0.685205172328992,"d":"0.69"},{"v":0.45195310494038,"d":"0.45"},{"v":-1.14575500981287,"d":"-1.15"},{"v":0.0998462084920303,"d":"0.10"},{"v":0.849451958661787,"d":"0.85"},"down","no"]
["MSTRG.3868","SLC15A4","ENST00000266771;ENST00000544112;ENST00000539703;ENST00000376744;ENST00000366292;ENST00000535272;ENST00000376740;ENST00000545031","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0015031(protein transport);GO:0005215(transporter activity);GO:0015293(symporter activity);GO:0055085(transmembrane transport);GO:0005886(plasma membrane);GO:0015992(proton transport);GO:0015833(peptide transport);GO:0006857(oligopeptide transport);GO:0043312(neutrophil degranulation);GO:0035579(specific granule membrane);GO:0006811(ion transport);GO:0005765(lysosomal membrane);GO:0015333(peptide:proton symporter activity);GO:0015333(peptide:proton symporter activity)","NA","NA","NA","solute carrier family 15 member 4 [Source:HGNC Symbol;Acc:HGNC:23090]",{"v":3.38876333879185,"d":"3.39"},{"v":7.37204421961426,"d":"7.37"},{"v":0.459677565386222,"d":"0.46"},{"v":-1.12130583790352,"d":"-1.12"},{"v":0.0998611505496904,"d":"0.10"},{"v":0.849451958661787,"d":"0.85"},"down","no"]
["MSTRG.15251","RP2","ENST00000218340;MSTRG.15251.2","GO:0006810(transport);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0015031(protein transport);GO:0000166(nucleotide binding);GO:0005654(nucleoplasm);GO:0003779(actin binding);GO:0005525(GTP binding);GO:0005886(plasma membrane);GO:0043547(positive regulation of GTPase activity);GO:0042995(cell projection);GO:0016604(nuclear body);GO:0005096(GTPase activator activity);GO:0007010(cytoskeleton organization);GO:0005515(protein binding);GO:0005794(Golgi apparatus);GO:0005814(centriole);GO:0036064(ciliary basal body);GO:1990075(periciliary membrane compartment);GO:0005929(cilium);GO:0070062(extracellular exosome);GO:0007601(visual perception);GO:0006457(protein folding);GO:0031410(cytoplasmic vesicle);GO:0051082(unfolded protein binding);GO:0006892(post-Golgi vesicle-mediated transport)","NA","NA","NA","RP2, ARL3 GTPase activating protein [Source:HGNC Symbol;Acc:HGNC:10274]",{"v":5.91105442519064,"d":"5.91"},{"v":12.81743,"d":"12.82"},{"v":0.46117313885784,"d":"0.46"},{"v":-1.11661960957577,"d":"-1.12"},{"v":0.0998857310633691,"d":"0.10"},{"v":0.849451958661787,"d":"0.85"},"down","no"]
["ENSG00000155034","FBXL18","ENST00000382368;ENST00000415009;ENST00000458142","GO:0005829(cytosol);GO:0000209(protein polyubiquitination);GO:0031146(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process);GO:0043687(post-translational protein modification);GO:0004842(ubiquitin-protein transferase activity);GO:0005515(protein binding);GO:0005515(protein binding)","NA","NA","NA","F-box and leucine rich repeat protein 18 [Source:HGNC Symbol;Acc:HGNC:21874]",{"v":0.356400658805031,"d":"0.36"},{"v":0.787526063679245,"d":"0.79"},{"v":0.452557286980398,"d":"0.45"},{"v":-1.14382766752836,"d":"-1.14"},{"v":0.0999920937536208,"d":"0.10"},{"v":0.849663772484305,"d":"0.85"},"down","no"]
["ENSG00000070950","RAD18","ENST00000264926;ENST00000418463;ENST00000427329;ENST00000469793;ENST00000415439;ENST00000429790;ENST00000473069","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0005654(nucleoplasm);GO:0016740(transferase activity);GO:0016567(protein ubiquitination);GO:0003677(DNA binding);GO:0006281(DNA repair);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0006974(cellular response to DNA damage stimulus);GO:0016604(nuclear body);GO:0005813(centrosome);GO:0005815(microtubule organizing center);GO:0061630(ubiquitin protein ligase activity);GO:0031625(ubiquitin protein ligase binding);GO:0006301(postreplication repair);GO:0000403(Y-form DNA binding);GO:0032403(protein complex binding);GO:0006513(protein monoubiquitination);GO:0042802(identical protein binding);GO:0005657(replication fork);GO:0003684(damaged DNA binding);GO:0035861(site of double-strand break);GO:0060548(negative regulation of cell death);GO:0042405(nuclear inclusion body);GO:0042769(DNA damage response, detection of DNA damage);GO:0031593(polyubiquitin binding);GO:0009411(response to UV);GO:0051984(positive regulation of chromosome segregation);GO:0043142(single-stranded DNA-dependent ATPase activity);GO:0051865(protein autoubiquitination);GO:0097505(Rad6-Rad18 complex);GO:0097505(Rad6-Rad18 complex)","NA","NA","NA","RAD18, E3 ubiquitin protein ligase [Source:HGNC Symbol;Acc:HGNC:18278]",{"v":0.770680402978662,"d":"0.77"},{"v":0.363211322067879,"d":"0.36"},{"v":2.12185126441249,"d":"2.12"},{"v":1.08532353108065,"d":"1.09"},{"v":0.100084046680893,"d":"0.10"},{"v":0.849663772484305,"d":"0.85"},"up","no"]
["MSTRG.8590","FOSL2","ENST00000436647;ENST00000264716;ENST00000379619;ENST00000460736","GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0006355(regulation of transcription, DNA-templated);GO:0006366(transcription from RNA polymerase II promoter);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0005515(protein binding);GO:0001228(transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0000977(RNA polymerase II regulatory region sequence-specific DNA binding);GO:0008219(cell death);GO:0003682(chromatin binding);GO:0003334(keratinocyte development);GO:0045893(positive regulation of transcription, DNA-templated);GO:0048146(positive regulation of fibroblast proliferation);GO:0048146(positive regulation of fibroblast proliferation)","04380(Osteoclast differentiation);04380(Osteoclast differentiation)","K09030","NA","FOS like 2, AP-1 transcription factor subunit [Source:HGNC Symbol;Acc:HGNC:3798]",{"v":12.5396292527595,"d":"12.54"},{"v":27.1380997526897,"d":"27.14"},{"v":0.462067328480384,"d":"0.46"},{"v":-1.1138250108053,"d":"-1.11"},{"v":0.100122313000766,"d":"0.10"},{"v":0.849663772484305,"d":"0.85"},"down","no"]
["ENSG00000165240","ATP7A","ENST00000341514;ENST00000343533","GO:0006810(transport);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005794(Golgi apparatus);GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0016787(hydrolase activity);GO:0005829(cytosol);GO:0005783(endoplasmic reticulum);GO:0006811(ion transport);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0006812(cation transport);GO:0099132(ATP hydrolysis coupled cation transmembrane transport);GO:0048471(perinuclear region of cytoplasm);GO:0030001(metal ion transport);GO:0005507(copper ion binding);GO:0019829(cation-transporting ATPase activity);GO:0048812(neuron projection morphogenesis);GO:0034220(ion transmembrane transport);GO:0005802(trans-Golgi network);GO:0016323(basolateral plasma membrane);GO:0005770(late endosome);GO:0030670(phagocytic vesicle membrane);GO:0043005(neuron projection);GO:0051216(cartilage development);GO:0032767(copper-dependent protein binding);GO:0006825(copper ion transport);GO:0019730(antimicrobial humoral response);GO:0031069(hair follicle morphogenesis);GO:0043086(negative regulation of catalytic activity);GO:0030199(collagen fibril organization);GO:0007005(mitochondrion organization);GO:0001568(blood vessel development);GO:0048286(lung alveolus development);GO:0007626(locomotory behavior);GO:0043025(neuronal cell body);GO:0006878(cellular copper ion homeostasis);GO:0006584(catecholamine metabolic process);GO:0043085(positive regulation of catalytic activity);GO:0019430(removal of superoxide radicals);GO:0043588(skin development);GO:1903136(cuprous ion binding);GO:0030198(extracellular matrix organization);GO:0042428(serotonin metabolic process);GO:0043473(pigmentation);GO:0021860(pyramidal neuron development);GO:0048251(elastic fiber assembly);GO:0042093(T-helper cell differentiation);GO:0004008(copper-exporting ATPase activity);GO:0005375(copper ion transmembrane transporter activity);GO:0015677(copper ion import);GO:0021702(cerebellar Purkinje cell differentiation);GO:0016532(superoxide dismutase copper chaperone activity);GO:0048365(Rac GTPase binding);GO:0051087(chaperone binding);GO:0001701(in utero embryonic development);GO:0001889(liver development);GO:0001974(blood vessel remodeling);GO:0002082(regulation of oxidative phosphorylation);GO:0006568(tryptophan metabolic process);GO:0007595(lactation);GO:0010041(response to iron(III) ion);GO:0010042(response to manganese ion);GO:0010043(response to zinc ion);GO:0010273(detoxification of copper ion);GO:0010288(response to lead ion);GO:0010468(regulation of gene expression);GO:0010592(positive regulation of lamellipodium assembly);GO:0015679(plasma membrane copper ion transport);GO:0018205(peptidyl-lysine modification);GO:0021954(central nervous system neuron development);GO:0034760(negative regulation of iron ion transmembrane transport);GO:0036120(cellular response to platelet-derived growth factor stimulus);GO:0042414(epinephrine metabolic process);GO:0042415(norepinephrine metabolic process);GO:0042417(dopamine metabolic process);GO:0045793(positive regulation of cell size);GO:0046688(response to copper ion);GO:0050679(positive regulation of epithelial cell proliferation);GO:0051353(positive regulation of oxidoreductase activity);GO:0051542(elastin biosynthetic process);GO:0060003(copper ion export);GO:0071230(cellular response to amino acid stimulus);GO:0071236(cellular response to antibiotic);GO:0071276(cellular response to cadmium ion);GO:0071279(cellular response to cobalt ion);GO:0071280(cellular response to copper ion);GO:0071281(cellular response to iron ion);GO:0071284(cellular response to lead ion);GO:0071456(cellular response to hypoxia);GO:1903036(positive regulation of response to wounding);GO:1904754(positive regulation of vascular associated smooth muscle cell migration);GO:1904959(regulation of cytochrome-c oxidase activity);GO:0005634(nucleus);GO:0005902(microvillus);GO:0016324(apical plasma membrane);GO:0030140(trans-Golgi network transport vesicle);GO:0030141(secretory granule);GO:0031252(cell leading edge);GO:0031526(brush border membrane);GO:0043204(perikaryon);GO:0045121(membrane raft);GO:0045121(membrane raft)","04978(Mineral absorption);01524(Platinum drug resistance);01524(Platinum drug resistance)","K17686","EC:3.6.3.54","ATPase copper transporting alpha [Source:HGNC Symbol;Acc:HGNC:869]",{"v":0.886986053347403,"d":"0.89"},{"v":1.93139181557041,"d":"1.93"},{"v":0.459247080885783,"d":"0.46"},{"v":-1.12265754373035,"d":"-1.12"},{"v":0.100206403797994,"d":"0.10"},{"v":0.849778531362986,"d":"0.85"},"down","no"]
["ENSG00000145730","PAM","ENST00000455264;ENST00000438793;ENST00000379799;ENST00000348126;ENST00000345721;ENST00000504456;ENST00000510208;ENST00000510006;ENST00000506260;ENST00000346918;ENST00000505372;ENST00000504691;ENST00000304400;ENST00000511429;ENST00000509636;ENST00000513648","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0046872(metal ion binding);GO:0004497(monooxygenase activity);GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0003824(catalytic activity);GO:0016829(lyase activity);GO:0008270(zinc ion binding);GO:0008152(metabolic process);GO:0005576(extracellular region);GO:0005507(copper ion binding);GO:0005515(protein binding);GO:0070062(extracellular exosome);GO:0016715(oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen);GO:0006518(peptide metabolic process);GO:0031418(L-ascorbic acid binding);GO:0004504(peptidylglycine monooxygenase activity);GO:0004598(peptidylamidoglycolate lyase activity);GO:0001519(peptide amidation);GO:0005509(calcium ion binding);GO:0019901(protein kinase binding);GO:0001666(response to hypoxia);GO:0001676(long-chain fatty acid metabolic process);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0007417(central nervous system development);GO:0007507(heart development);GO:0007595(lactation);GO:0009268(response to pH);GO:0009404(toxin metabolic process);GO:0018032(protein amidation);GO:0019538(protein metabolic process);GO:0022602(ovulation cycle process);GO:0032355(response to estradiol);GO:0032956(regulation of actin cytoskeleton organization);GO:0042476(odontogenesis);GO:0042493(response to drug);GO:0046688(response to copper ion);GO:0050708(regulation of protein secretion);GO:0051260(protein homooligomerization);GO:0051384(response to glucocorticoid);GO:0060135(maternal process involved in female pregnancy);GO:0060173(limb development);GO:0005615(extracellular space);GO:0005802(trans-Golgi network);GO:0005886(plasma membrane);GO:0009986(cell surface);GO:0030141(secretory granule);GO:0030667(secretory granule membrane);GO:0043005(neuron projection);GO:0043025(neuronal cell body);GO:0043204(perikaryon);GO:0048471(perinuclear region of cytoplasm);GO:0048471(perinuclear region of cytoplasm)","NA","NA","NA","peptidylglycine alpha-amidating monooxygenase [Source:HGNC Symbol;Acc:HGNC:8596]",{"v":1.56720703764413,"d":"1.57"},{"v":3.3998825557314,"d":"3.40"},{"v":0.460959169016644,"d":"0.46"},{"v":-1.11728913005932,"d":"-1.12"},{"v":0.100291856064308,"d":"0.10"},{"v":0.849889592538247,"d":"0.85"},"down","no"]
["MSTRG.463","PPT1","ENST00000439754;ENST00000642050;ENST00000641319;MSTRG.463.1;ENST00000527311;ENST00000641924;ENST00000530704;ENST00000641083;ENST00000372775;ENST00000641691;ENST00000529905;ENST00000433473;ENST00000641471;ENST00000641381;ENST00000449045;ENST00000526547;ENST00000372779;ENST00000641236","GO:0005615(extracellular space);GO:0044257(cellular protein catabolic process);GO:0005764(lysosome);GO:0043025(neuronal cell body);GO:0030424(axon);GO:0007601(visual perception);GO:0030425(dendrite);GO:0008474(palmitoyl-(protein) hydrolase activity);GO:0002084(protein depalmitoylation);GO:0007040(lysosome organization);GO:0007269(neurotransmitter secretion);GO:0007625(grooming behavior);GO:0008306(associative learning);GO:0008344(adult locomotory behavior);GO:0032429(regulation of phospholipase A2 activity);GO:0044265(cellular macromolecule catabolic process);GO:0008021(synaptic vesicle);GO:0043005(neuron projection);GO:0045202(synapse);GO:0098599(palmitoyl hydrolase activity);GO:0005634(nucleus);GO:0016020(membrane);GO:0015031(protein transport);GO:0016787(hydrolase activity);GO:0005794(Golgi apparatus);GO:0016042(lipid catabolic process);GO:0005829(cytosol);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0007399(nervous system development);GO:0045121(membrane raft);GO:0050896(response to stimulus);GO:0048666(neuron development);GO:0070062(extracellular exosome);GO:0043524(negative regulation of neuron apoptotic process);GO:0016290(palmitoyl-CoA hydrolase activity);GO:0043066(negative regulation of apoptotic process);GO:0030308(negative regulation of cell growth);GO:0048260(positive regulation of receptor-mediated endocytosis);GO:0007268(chemical synaptic transmission);GO:0007420(brain development);GO:0043202(lysosomal lumen);GO:0046949(fatty-acyl-CoA biosynthetic process);GO:0030163(protein catabolic process);GO:0031579(membrane raft organization);GO:0007042(lysosomal lumen acidification);GO:0030149(sphingolipid catabolic process);GO:0050803(regulation of synapse structure or activity);GO:0006898(receptor-mediated endocytosis);GO:0006907(pinocytosis);GO:0048549(positive regulation of pinocytosis);GO:0051181(cofactor transport);GO:0051186(cofactor metabolic process);GO:0051186(cofactor metabolic process)","00062(Fatty acid elongation);04142(Lysosome);04142(Lysosome)","K01074","EC:3.1.2.22","palmitoyl-protein thioesterase 1 [Source:HGNC Symbol;Acc:HGNC:9325]",{"v":22.7015429404949,"d":"22.70"},{"v":49.1093917223095,"d":"49.11"},{"v":0.46226479588388,"d":"0.46"},{"v":-1.11320859763392,"d":"-1.11"},{"v":0.100496394841618,"d":"0.10"},{"v":0.849889592538247,"d":"0.85"},"down","no"]
["MSTRG.10041","LINC00649","ENST00000381181;ENST00000597626;ENST00000599421;ENST00000427447;ENST00000622171;ENST00000400353;ENST00000596365;ENST00000594752;ENST00000595747;ENST00000628906;ENST00000594370;ENST00000600155;ENST00000609132","NA","NA","NA","NA","long intergenic non-protein coding RNA 649 [Source:HGNC Symbol;Acc:HGNC:44305]",{"v":0.229143029715402,"d":"0.23"},{"v":0.509405755929129,"d":"0.51"},{"v":0.449824186413947,"d":"0.45"},{"v":-1.15256686000251,"d":"-1.15"},{"v":0.100576487775798,"d":"0.10"},{"v":0.849889592538247,"d":"0.85"},"down","no"]
["ENSG00000135185","TMEM243","ENST00000433078;ENST00000492231;ENST00000423734;ENST00000455575;ENST00000474074;ENST00000465976;ENST00000481425;ENST00000257637","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016021(integral component of membrane)","NA","NA","NA","transmembrane protein 243 [Source:HGNC Symbol;Acc:HGNC:21707]",{"v":0.586569212778967,"d":"0.59"},{"v":1.31321358819933,"d":"1.31"},{"v":0.446667029681948,"d":"0.45"},{"v":-1.16272832753035,"d":"-1.16"},{"v":0.100599032839904,"d":"0.10"},{"v":0.849889592538247,"d":"0.85"},"down","no"]
["MSTRG.14371","RAB2A","ENST00000262646;ENST00000531289;ENST00000396696;ENST00000429861;ENST00000481569;ENST00000452437;ENST00000531098;ENST00000466595;ENST00000525529;ENST00000529579;ENST00000530071","GO:0006810(transport);GO:0005634(nucleus);GO:0016020(membrane);GO:0015031(protein transport);GO:0005525(GTP binding);GO:0000166(nucleotide binding);GO:0003924(GTPase activity);GO:0005794(Golgi apparatus);GO:0005765(lysosomal membrane);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005515(protein binding);GO:0042470(melanosome);GO:0000139(Golgi membrane);GO:0016192(vesicle-mediated transport);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0043687(post-translational protein modification);GO:0019003(GDP binding);GO:0007030(Golgi organization);GO:0006888(ER to Golgi vesicle-mediated transport);GO:0033116(endoplasmic reticulum-Golgi intermediate compartment membrane);GO:0033116(endoplasmic reticulum-Golgi intermediate compartment membrane)","04152(AMPK signaling pathway);04152(AMPK signaling pathway)","K07877","NA","RAB2A, member RAS oncogene family [Source:HGNC Symbol;Acc:HGNC:9763]",{"v":5.55347996763353,"d":"5.55"},{"v":12.0269741600637,"d":"12.03"},{"v":0.461752049495059,"d":"0.46"},{"v":-1.11480973023667,"d":"-1.11"},{"v":0.100633999377548,"d":"0.10"},{"v":0.849889592538247,"d":"0.85"},"down","no"]
["ENSG00000175265","GOLGA8A","ENST00000473125;ENST00000565885;ENST00000432566;ENST00000359187;ENST00000569781","GO:0016020(membrane);GO:0005794(Golgi apparatus);GO:0005829(cytosol);GO:0032580(Golgi cisterna membrane);GO:0032580(Golgi cisterna membrane)","NA","NA","NA","golgin A8 family member A [Source:HGNC Symbol;Acc:HGNC:31972]",{"v":3.97430920696296,"d":"3.97"},{"v":1.89913256088889,"d":"1.90"},{"v":2.09269710225114,"d":"2.09"},{"v":1.06536351049298,"d":"1.07"},{"v":0.100776754071427,"d":"0.10"},{"v":0.849889592538247,"d":"0.85"},"up","no"]
["MSTRG.1134","DEDD","ENST00000368006;ENST00000463227;ENST00000458050;ENST00000368005;ENST00000490843;ENST00000473679;ENST00000486041;ENST00000489249;ENST00000545495;ENST00000472996;ENST00000496632;ENST00000464113","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0042981(regulation of apoptotic process);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0006915(apoptotic process);GO:0005730(nucleolus);GO:0008625(extrinsic apoptotic signaling pathway via death domain receptors);GO:0007283(spermatogenesis);GO:0042177(negative regulation of protein catabolic process);GO:0046697(decidualization);GO:1901837(negative regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter);GO:1901837(negative regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter)","NA","NA","NA","death effector domain containing [Source:HGNC Symbol;Acc:HGNC:2755]",{"v":3.56352543069833,"d":"3.56"},{"v":7.74179454767813,"d":"7.74"},{"v":0.460297080832128,"d":"0.46"},{"v":-1.11936280175499,"d":"-1.12"},{"v":0.100911920540597,"d":"0.10"},{"v":0.849889592538247,"d":"0.85"},"down","no"]
["MSTRG.4537","ALDH6A1","ENST00000553458;ENST00000554501;ENST00000554231;ENST00000556852;ENST00000555126","GO:0003723(RNA binding);GO:0005654(nucleoplasm);GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0005739(mitochondrion);GO:0008152(metabolic process);GO:0004491(methylmalonate-semialdehyde dehydrogenase (acylating) activity);GO:0050873(brown fat cell differentiation);GO:0070062(extracellular exosome);GO:0005759(mitochondrial matrix);GO:0009083(branched-chain amino acid catabolic process);GO:0000062(fatty-acyl-CoA binding);GO:0018478(malonate-semialdehyde dehydrogenase (acetylating) activity);GO:0006210(thymine catabolic process);GO:0006573(valine metabolic process);GO:0006574(valine catabolic process);GO:0019859(thymine metabolic process);GO:0019859(thymine metabolic process)","00640(Propanoate metabolism);00562(Inositol phosphate metabolism);00280(Valine, leucine and isoleucine degradation);00410(beta-Alanine metabolism);00410(beta-Alanine metabolism)","K00140","EC:1.2.1.18;EC:1.2.1.27","aldehyde dehydrogenase 6 family member A1 [Source:HGNC Symbol;Acc:HGNC:7179]",{"v":1.08898422170659,"d":"1.09"},{"v":0.510745931287425,"d":"0.51"},{"v":2.13214468289863,"d":"2.13"},{"v":1.09230533970032,"d":"1.09"},{"v":0.100928486530812,"d":"0.10"},{"v":0.849889592538247,"d":"0.85"},"up","no"]
["ENSG00000166927","MS4A7","ENST00000358246;ENST00000530614;ENST00000528587;ENST00000528808;ENST00000530027;ENST00000300184;ENST00000528215;ENST00000534016;ENST00000528500;ENST00000533849;ENST00000534310","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016021(integral component of membrane)","NA","NA","NA","membrane spanning 4-domains A7 [Source:HGNC Symbol;Acc:HGNC:13378]",{"v":1.4832165124195,"d":"1.48"},{"v":3.23346036430543,"d":"3.23"},{"v":0.458708734701965,"d":"0.46"},{"v":-1.12434971550056,"d":"-1.12"},{"v":0.100935125512556,"d":"0.10"},{"v":0.849889592538247,"d":"0.85"},"down","no"]
["MSTRG.5199","INTS14","ENST00000313182;ENST00000573314;ENST00000569180;ENST00000561769;ENST00000563729;ENST00000567923;ENST00000567940;ENST00000567744;ENST00000564306;ENST00000420799;ENST00000569565;ENST00000431261","GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0042795(snRNA transcription from RNA polymerase II promoter);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005737(cytoplasm);GO:0005737(cytoplasm)","NA","NA","NA","integrator complex subunit 14 [Source:HGNC Symbol;Acc:HGNC:25372]",{"v":2.82863096769596,"d":"2.83"},{"v":1.34686846603325,"d":"1.35"},{"v":2.10015383018562,"d":"2.10"},{"v":1.07049500499514,"d":"1.07"},{"v":0.10094499349217,"d":"0.10"},{"v":0.849889592538247,"d":"0.85"},"up","no"]
["ENSG00000108384","RAD51C","ENST00000337432;ENST00000487525;ENST00000584804;ENST00000486827;ENST00000581221;ENST00000421782;ENST00000461706;ENST00000476741;ENST00000461271;ENST00000425173;ENST00000487921;ENST00000622327;ENST00000583539;ENST00000578151;ENST00000475762","GO:0005524(ATP binding);GO:0003677(DNA binding);GO:0008094(DNA-dependent ATPase activity);GO:0006281(DNA repair);GO:0043231(intracellular membrane-bounded organelle);GO:0005634(nucleus);GO:0005829(cytosol);GO:0005739(mitochondrion);GO:0030054(cell junction);GO:0005737(cytoplasm);GO:0000166(nucleotide binding);GO:0005515(protein binding);GO:0006310(DNA recombination);GO:0006974(cellular response to DNA damage stimulus);GO:0048471(perinuclear region of cytoplasm);GO:0003690(double-stranded DNA binding);GO:0006312(mitotic recombination);GO:0005654(nucleoplasm);GO:0003697(single-stranded DNA binding);GO:0000400(four-way junction DNA binding);GO:0010971(positive regulation of G2/M transition of mitotic cell cycle);GO:0000724(double-strand break repair via homologous recombination);GO:0000150(recombinase activity);GO:0000707(meiotic DNA recombinase assembly);GO:0000731(DNA synthesis involved in DNA repair);GO:0000732(strand displacement);GO:0007596(blood coagulation);GO:0010212(response to ionizing radiation);GO:0042148(strand invasion);GO:0005657(replication fork);GO:0033063(Rad51B-Rad51C-Rad51D-XRCC2 complex);GO:0048476(Holliday junction resolvase complex);GO:0008821(crossover junction endodeoxyribonuclease activity);GO:0000722(telomere maintenance via recombination);GO:0007062(sister chromatid cohesion);GO:0007066(female meiosis sister chromatid cohesion);GO:0007131(reciprocal meiotic recombination);GO:0007141(male meiosis I);GO:0007283(spermatogenesis);GO:0033065(Rad51C-XRCC3 complex);GO:0033065(Rad51C-XRCC3 complex)","03440(Homologous recombination);03460(Fanconi anemia pathway);03460(Fanconi anemia pathway)","K10870","NA","RAD51 paralog C [Source:HGNC Symbol;Acc:HGNC:9820]",{"v":0.701092961601846,"d":"0.70"},{"v":0.327025460613052,"d":"0.33"},{"v":2.14384825049265,"d":"2.14"},{"v":1.10020279011947,"d":"1.10"},{"v":0.101041302113642,"d":"0.10"},{"v":0.849889592538247,"d":"0.85"},"up","no"]
["MSTRG.776","CD53","MSTRG.776.1;ENST00000271324;ENST00000471220;ENST00000464329;ENST00000497404;ENST00000476408","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005886(plasma membrane);GO:0030054(cell junction);GO:0005887(integral component of plasma membrane);GO:0005515(protein binding);GO:0070062(extracellular exosome);GO:0007166(cell surface receptor signaling pathway);GO:0043312(neutrophil degranulation);GO:0035579(specific granule membrane);GO:0070821(tertiary granule membrane);GO:0007165(signal transduction);GO:0005911(cell-cell junction);GO:1901741(positive regulation of myoblast fusion);GO:0001772(immunological synapse);GO:0009986(cell surface);GO:0009986(cell surface)","NA","NA","NA","CD53 molecule [Source:HGNC Symbol;Acc:HGNC:1686]",{"v":55.6226034114964,"d":"55.62"},{"v":120.069084176551,"d":"120.07"},{"v":0.463254998511592,"d":"0.46"},{"v":-1.110121551902,"d":"-1.11"},{"v":0.101163839067563,"d":"0.10"},{"v":0.849889592538247,"d":"0.85"},"down","no"]
["ENSG00000090447","TFAP4","ENST00000204517;ENST00000573476;ENST00000575320;ENST00000575300;ENST00000574639;ENST00000575672","GO:0005634(nucleus);GO:0046983(protein dimerization activity);GO:0006366(transcription from RNA polymerase II promoter);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0005739(mitochondrion);GO:0003677(DNA binding);GO:0042803(protein homodimerization activity);GO:0005515(protein binding);GO:0045893(positive regulation of transcription, DNA-templated);GO:0008285(negative regulation of cell proliferation);GO:0071157(negative regulation of cell cycle arrest);GO:0043065(positive regulation of apoptotic process);GO:0043565(sequence-specific DNA binding);GO:0044212(transcription regulatory region DNA binding);GO:0045736(negative regulation of cyclin-dependent protein serine/threonine kinase activity);GO:0045892(negative regulation of transcription, DNA-templated);GO:0070888(E-box binding);GO:0006461(protein complex assembly);GO:1901990(regulation of mitotic cell cycle phase transition);GO:0042826(histone deacetylase binding);GO:0017053(transcriptional repressor complex);GO:0003705(transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding);GO:0043392(negative regulation of DNA binding);GO:0043922(negative regulation by host of viral transcription);GO:0043923(positive regulation by host of viral transcription);GO:0006978(DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:0001077(transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0010629(negative regulation of gene expression);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0071549(cellular response to dexamethasone stimulus);GO:2001269(positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway);GO:2001269(positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway)","05205(Proteoglycans in cancer);05205(Proteoglycans in cancer)","K09108","NA","transcription factor AP-4 [Source:HGNC Symbol;Acc:HGNC:11745]",{"v":1.12250045481124,"d":"1.12"},{"v":0.532256928562349,"d":"0.53"},{"v":2.10894474937727,"d":"2.11"},{"v":1.07652129956805,"d":"1.08"},{"v":0.101183904409917,"d":"0.10"},{"v":0.849889592538247,"d":"0.85"},"up","no"]
["MSTRG.7773",null,"MSTRG.7773.1","NA","NA","NA","NA",null,{"v":6.17162,"d":"6.17"},{"v":2.91311,"d":"2.91"},{"v":2.11856744166887,"d":"2.12"},{"v":1.08308905563715,"d":"1.08"},{"v":0.101277719738215,"d":"0.10"},{"v":0.849889592538247,"d":"0.85"},"up","no"]
["MSTRG.8917","AC006453.2","ENST00000636560;ENST00000635968;ENST00000637196;ENST00000636531","NA","NA","NA","NA",null,{"v":0.574158454846727,"d":"0.57"},{"v":1.29387307000828,"d":"1.29"},{"v":0.443751762174827,"d":"0.44"},{"v":-1.17217524631037,"d":"-1.17"},{"v":0.10127815689191,"d":"0.10"},{"v":0.849889592538247,"d":"0.85"},"down","no"]
["ENSG00000185684","EP400NL","ENST00000389560;ENST00000488030;ENST00000392352;ENST00000454179;ENST00000475841;ENST00000332441;ENST00000613241;ENST00000446190;ENST00000641289;ENST00000537558","NA","NA","NA","NA","EP400 N-terminal like [Source:HGNC Symbol;Acc:HGNC:26602]",{"v":0.341624354841226,"d":"0.34"},{"v":0.159486371849887,"d":"0.16"},{"v":2.14202850612698,"d":"2.14"},{"v":1.09897767960936,"d":"1.10"},{"v":0.101470331550217,"d":"0.10"},{"v":0.850346369044331,"d":"0.85"},"up","no"]
["MSTRG.10418","TXN2","ENST00000216185;ENST00000487725;ENST00000416967;ENST00000411915;ENST00000403313","GO:0005730(nucleolus);GO:0055114(oxidation-reduction process);GO:0005739(mitochondrion);GO:0045454(cell redox homeostasis);GO:0005515(protein binding);GO:0015035(protein disulfide oxidoreductase activity);GO:0006662(glycerol ether metabolic process);GO:0005759(mitochondrial matrix);GO:0034599(cellular response to oxidative stress);GO:0008113(peptide-methionine (S)-S-oxide reductase activity);GO:0032403(protein complex binding);GO:0033743(peptide-methionine (R)-S-oxide reductase activity);GO:0001666(response to hypoxia);GO:0006979(response to oxidative stress);GO:0007584(response to nutrient);GO:0009725(response to hormone);GO:0009749(response to glucose);GO:0014070(response to organic cyclic compound);GO:0031669(cellular response to nutrient levels);GO:0042493(response to drug);GO:0048678(response to axon injury);GO:0030425(dendrite);GO:0043025(neuronal cell body);GO:0005623(cell);GO:0005623(cell)","04621(NOD-like receptor signaling pathway);05418(Fluid shear stress and atherosclerosis);05418(Fluid shear stress and atherosclerosis)","K03671","NA","thioredoxin 2 [Source:HGNC Symbol;Acc:HGNC:17772]",{"v":6.10192789365854,"d":"6.10"},{"v":13.1982793678049,"d":"13.20"},{"v":0.462327529491702,"d":"0.46"},{"v":-1.11301282385869,"d":"-1.11"},{"v":0.101478947006676,"d":"0.10"},{"v":0.850346369044331,"d":"0.85"},"down","no"]
["ENSG00000148655","LRMDA","ENST00000611255;ENST00000598708;ENST00000488655;ENST00000593699;ENST00000372499;ENST00000611306;ENST00000593817","GO:0030154(cell differentiation);GO:0030318(melanocyte differentiation);GO:0030318(melanocyte differentiation)","NA","NA","NA","leucine rich melanocyte differentiation associated [Source:HGNC Symbol;Acc:HGNC:23405]",{"v":0.13814303429878,"d":"0.14"},{"v":0.315725088719512,"d":"0.32"},{"v":0.437542150543207,"d":"0.44"},{"v":-1.19250608948415,"d":"-1.19"},{"v":0.101590988498261,"d":"0.10"},{"v":0.850346369044331,"d":"0.85"},"down","no"]
["MSTRG.12766","HCG18;HCG17","ENST00000438412;ENST00000426882;ENST00000412685;ENST00000453558;ENST00000602319;ENST00000455957;ENST00000602550;ENST00000602591;ENST00000444126;ENST00000602516;ENST00000449544;ENST00000454269;ENST00000602861;ENST00000454129","NA","NA","NA","NA","HLA complex group 18 (non-protein coding) [Source:HGNC Symbol;Acc:HGNC:31337];HLA complex group 17 (non-protein coding) [Source:HGNC Symbol;Acc:HGNC:31339]",{"v":0.273178377156209,"d":"0.27"},{"v":0.59735777369253,"d":"0.60"},{"v":0.457311161228511,"d":"0.46"},{"v":-1.12875196460642,"d":"-1.13"},{"v":0.101615049414947,"d":"0.10"},{"v":0.850346369044331,"d":"0.85"},"down","no"]
["ENSG00000173085","COQ2","ENST00000503915;ENST00000311469;ENST00000311461;ENST00000503391","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016765(transferase activity, transferring alkyl or aryl (other than methyl) groups);GO:0004659(prenyltransferase activity);GO:0016740(transferase activity);GO:0005743(mitochondrial inner membrane);GO:0005739(mitochondrion);GO:0006744(ubiquinone biosynthetic process);GO:0031305(integral component of mitochondrial inner membrane);GO:0002083(4-hydroxybenzoate decaprenyltransferase activity);GO:0047293(4-hydroxybenzoate nonaprenyltransferase activity);GO:0008299(isoprenoid biosynthetic process);GO:0006071(glycerol metabolic process);GO:0006071(glycerol metabolic process)","00130(Ubiquinone and other terpenoid-quinone biosynthesis);00130(Ubiquinone and other terpenoid-quinone biosynthesis)","K06125","EC:2.5.1.39","coenzyme Q2, polyprenyltransferase [Source:HGNC Symbol;Acc:HGNC:25223]",{"v":0.743922009012257,"d":"0.74"},{"v":1.64006355335256,"d":"1.64"},{"v":0.453593403433396,"d":"0.45"},{"v":-1.14052843543422,"d":"-1.14"},{"v":0.10188670312936,"d":"0.10"},{"v":0.851234307132088,"d":"0.85"},"down","no"]
["MSTRG.8679","FOXN2","ENST00000340553;MSTRG.8679.1;ENST00000616844","GO:0005634(nucleus);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0043565(sequence-specific DNA binding);GO:0043231(intracellular membrane-bounded organelle);GO:0006351(transcription, DNA-templated);GO:0005515(protein binding);GO:0030154(cell differentiation);GO:0045893(positive regulation of transcription, DNA-templated);GO:0035914(skeletal muscle cell differentiation);GO:0035914(skeletal muscle cell differentiation)","NA","NA","NA","forkhead box N2 [Source:HGNC Symbol;Acc:HGNC:5281]",{"v":2.83723723969354,"d":"2.84"},{"v":6.13148147683327,"d":"6.13"},{"v":0.462732742553907,"d":"0.46"},{"v":-1.11174890856495,"d":"-1.11"},{"v":0.101890420245452,"d":"0.10"},{"v":0.851234307132088,"d":"0.85"},"down","no"]
["MSTRG.1452","CCSAP","ENST00000366687;ENST00000483092","GO:0005737(cytoplasm);GO:0051301(cell division);GO:0005856(cytoskeleton);GO:0042995(cell projection);GO:0007049(cell cycle);GO:0007275(multicellular organism development);GO:0005874(microtubule);GO:0008017(microtubule binding);GO:0005813(centrosome);GO:0005815(microtubule organizing center);GO:0005819(spindle);GO:0030424(axon);GO:0005929(cilium);GO:0005814(centriole);GO:0005930(axoneme);GO:0036064(ciliary basal body);GO:0035869(ciliary transition zone);GO:1901673(regulation of mitotic spindle assembly);GO:0072686(mitotic spindle);GO:0045995(regulation of embryonic development);GO:0048666(neuron development);GO:0061673(mitotic spindle astral microtubule);GO:0060296(regulation of cilium beat frequency involved in ciliary motility);GO:1990755(mitotic spindle microtubule depolymerization);GO:1990755(mitotic spindle microtubule depolymerization)","NA","NA","NA","centriole, cilia and spindle associated protein [Source:HGNC Symbol;Acc:HGNC:29578]",{"v":0.947390926393102,"d":"0.95"},{"v":2.05602347197829,"d":"2.06"},{"v":0.460787991628096,"d":"0.46"},{"v":-1.11782497499154,"d":"-1.12"},{"v":0.101933222960013,"d":"0.10"},{"v":0.851234307132088,"d":"0.85"},"down","no"]
["ENSG00000281852","LINC00891","ENST00000627173","NA","NA","NA","NA","long intergenic non-protein coding RNA 891 [Source:HGNC Symbol;Acc:HGNC:48577]",{"v":1.255198,"d":"1.26"},{"v":0.593084,"d":"0.59"},{"v":2.11639160725968,"d":"2.12"},{"v":1.08160660173294,"d":"1.08"},{"v":0.102005941365365,"d":"0.10"},{"v":0.851251244575,"d":"0.85"},"up","no"]
["MSTRG.11051","LINC00877","ENST00000488545;ENST00000468646;ENST00000470712;ENST00000498432;ENST00000608654;ENST00000462492;ENST00000464271","NA","NA","NA","NA","long intergenic non-protein coding RNA 877 [Source:HGNC Symbol;Acc:HGNC:27706]",{"v":1.18762178782288,"d":"1.19"},{"v":2.58114684378844,"d":"2.58"},{"v":0.460113995715085,"d":"0.46"},{"v":-1.11993675398271,"d":"-1.12"},{"v":0.102349516341753,"d":"0.10"},{"v":0.85321670409418,"d":"0.85"},"down","no"]
["MSTRG.8382","FPR1","ENST00000304748;ENST00000595042;ENST00000600815;ENST00000594900;MSTRG.8382.1","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0004930(G-protein coupled receptor activity);GO:0007186(G-protein coupled receptor signaling pathway);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0004871(signal transducer activity);GO:0007165(signal transduction);GO:0004982(N-formyl peptide receptor activity);GO:0006935(chemotaxis);GO:0060326(cell chemotaxis);GO:0005887(integral component of plasma membrane);GO:0006954(inflammatory response);GO:0043312(neutrophil degranulation);GO:0005622(intracellular);GO:0030667(secretory granule membrane);GO:0035577(azurophil granule membrane);GO:0101003(ficolin-1-rich granule membrane);GO:0007188(adenylate cyclase-modulating G-protein coupled receptor signaling pathway);GO:0004875(complement receptor activity);GO:0002430(complement receptor mediated signaling pathway);GO:0007204(positive regulation of cytosolic calcium ion concentration);GO:0050900(leukocyte migration);GO:0007263(nitric oxide mediated signal transduction);GO:0000187(activation of MAPK activity);GO:0005124(scavenger receptor binding);GO:0050786(RAGE receptor binding);GO:0007200(phospholipase C-activating G-protein coupled receptor signaling pathway);GO:0007200(phospholipase C-activating G-protein coupled receptor signaling pathway)","04015(Rap1 signaling pathway);04080(Neuroactive ligand-receptor interaction);05150(Staphylococcus aureus infection);05150(Staphylococcus aureus infection)","K04172","NA","formyl peptide receptor 1 [Source:HGNC Symbol;Acc:HGNC:3826]",{"v":75.9154395386322,"d":"75.92"},{"v":163.380743407394,"d":"163.38"},{"v":0.464653532328073,"d":"0.46"},{"v":-1.10577271952837,"d":"-1.11"},{"v":0.102425101670692,"d":"0.10"},{"v":0.85321670409418,"d":"0.85"},"down","no"]
["ENSG00000169116","PARM1","ENST00000307428;ENST00000513238","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0043231(intracellular membrane-bounded organelle);GO:0005634(nucleus);GO:0005829(cytosol);GO:0005794(Golgi apparatus);GO:0005886(plasma membrane);GO:0000139(Golgi membrane);GO:0005768(endosome);GO:0005769(early endosome);GO:0010008(endosome membrane);GO:0005770(late endosome);GO:0051973(positive regulation of telomerase activity);GO:0051973(positive regulation of telomerase activity)","NA","NA","NA","prostate androgen-regulated mucin-like protein 1 [Source:HGNC Symbol;Acc:HGNC:24536]",{"v":1.35238864382201,"d":"1.35"},{"v":0.643603980333731,"d":"0.64"},{"v":2.10127451840921,"d":"2.10"},{"v":1.07126465343218,"d":"1.07"},{"v":0.102454023760188,"d":"0.10"},{"v":0.85321670409418,"d":"0.85"},"up","no"]
["MSTRG.15435","SASH3;AL023653.1","ENST00000356892;ENST00000476532;ENST00000432513","GO:0002639(positive regulation of immunoglobulin production);GO:0002726(positive regulation of T cell cytokine production);GO:0002821(positive regulation of adaptive immune response);GO:0030890(positive regulation of B cell proliferation);GO:0032729(positive regulation of interferon-gamma production);GO:0032733(positive regulation of interleukin-10 production);GO:0032743(positive regulation of interleukin-2 production);GO:0032753(positive regulation of interleukin-4 production);GO:0032760(positive regulation of tumor necrosis factor production);GO:0042102(positive regulation of T cell proliferation);GO:0043372(positive regulation of CD4-positive, alpha-beta T cell differentiation);GO:0046622(positive regulation of organ growth);GO:0048873(homeostasis of number of cells within a tissue);GO:0051251(positive regulation of lymphocyte activation);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005737(cytoplasm)","NA","NA","NA","SAM and SH3 domain containing 3 [Source:HGNC Symbol;Acc:HGNC:15975]",{"v":64.5268221438849,"d":"64.53"},{"v":31.1049278067831,"d":"31.10"},{"v":2.07448872875421,"d":"2.07"},{"v":1.05275581868723,"d":"1.05"},{"v":0.102657873271515,"d":"0.10"},{"v":0.854130806290258,"d":"0.85"},"up","no"]
["MSTRG.9591","TMX4","ENST00000246024;ENST00000462384","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0055114(oxidation-reduction process);GO:0045454(cell redox homeostasis);GO:0005783(endoplasmic reticulum);GO:0006457(protein folding);GO:0003756(protein disulfide isomerase activity);GO:0034976(response to endoplasmic reticulum stress);GO:0005623(cell);GO:0005623(cell)","NA","NA","NA","thioredoxin related transmembrane protein 4 [Source:HGNC Symbol;Acc:HGNC:25237]",{"v":7.54100941708466,"d":"7.54"},{"v":16.2280425626995,"d":"16.23"},{"v":0.46469001963415,"d":"0.46"},{"v":-1.10565943514511,"d":"-1.11"},{"v":0.102705647526017,"d":"0.10"},{"v":0.854130806290258,"d":"0.85"},"down","no"]
["ENSG00000174099","MSRB3","ENST00000614640;ENST00000355192;ENST00000540804;ENST00000308259","GO:0046872(metal ion binding);GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0005783(endoplasmic reticulum);GO:0005739(mitochondrion);GO:0005515(protein binding);GO:0006979(response to oxidative stress);GO:0016671(oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor);GO:0033743(peptide-methionine (R)-S-oxide reductase activity);GO:0030091(protein repair);GO:0005829(cytosol);GO:0008270(zinc ion binding);GO:0008270(zinc ion binding)","NA","NA","NA","methionine sulfoxide reductase B3 [Source:HGNC Symbol;Acc:HGNC:27375]",{"v":0.595799399758246,"d":"0.60"},{"v":1.29740438767052,"d":"1.30"},{"v":0.459224128899394,"d":"0.46"},{"v":-1.12272964771488,"d":"-1.12"},{"v":0.102800131920487,"d":"0.10"},{"v":0.8543265621715,"d":"0.85"},"down","no"]
["ENSG00000148600","CDHR1","ENST00000459673;ENST00000332904;ENST00000623527;ENST00000624091","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005509(calcium ion binding);GO:0007155(cell adhesion);GO:0007156(homophilic cell adhesion via plasma membrane adhesion molecules);GO:0005886(plasma membrane);GO:0009987(cellular process);GO:0045494(photoreceptor cell maintenance);GO:0005887(integral component of plasma membrane);GO:0042622(photoreceptor outer segment membrane);GO:0042622(photoreceptor outer segment membrane)","NA","NA","NA","cadherin related family member 1 [Source:HGNC Symbol;Acc:HGNC:14550]",{"v":0.399550826673654,"d":"0.40"},{"v":0.187882316258352,"d":"0.19"},{"v":2.12660155905382,"d":"2.13"},{"v":1.088549754679,"d":"1.09"},{"v":0.102994943663365,"d":"0.10"},{"v":0.854645922980578,"d":"0.85"},"up","no"]
["MSTRG.241","RCAN3","ENST00000374395;MSTRG.241.6;ENST00000538532;ENST00000425530;ENST00000412742;ENST00000630217;ENST00000618490;ENST00000616511;ENST00000436717;ENST00000482807","GO:0005622(intracellular);GO:0003676(nucleic acid binding);GO:0050790(regulation of catalytic activity);GO:0005515(protein binding);GO:0019722(calcium-mediated signaling);GO:0005737(cytoplasm);GO:0003723(RNA binding);GO:0009653(anatomical structure morphogenesis);GO:0031013(troponin I binding);GO:0008597(calcium-dependent protein serine/threonine phosphatase regulator activity);GO:0070884(regulation of calcineurin-NFAT signaling cascade);GO:0070884(regulation of calcineurin-NFAT signaling cascade)","NA","NA","NA","RCAN family member 3 [Source:HGNC Symbol;Acc:HGNC:3042]",{"v":5.36948059717514,"d":"5.37"},{"v":2.58499356257062,"d":"2.58"},{"v":2.07717368233425,"d":"2.08"},{"v":1.05462185179465,"d":"1.05"},{"v":0.103038613012167,"d":"0.10"},{"v":0.854645922980578,"d":"0.85"},"up","no"]
["MSTRG.3283","KIAA1551","MSTRG.3283.1;MSTRG.3283.8;MSTRG.3283.11;ENST00000312561;MSTRG.3283.4;ENST00000535596;ENST00000541981;ENST00000540924;ENST00000381054;ENST00000543763;ENST00000535606;ENST00000397578","NA","NA","NA","NA","KIAA1551 [Source:HGNC Symbol;Acc:HGNC:25559]",{"v":18.470633377682,"d":"18.47"},{"v":39.7005191878984,"d":"39.70"},{"v":0.465249164381514,"d":"0.47"},{"v":-1.10392453577699,"d":"-1.10"},{"v":0.103051476512855,"d":"0.10"},{"v":0.854645922980578,"d":"0.85"},"down","no"]
["ENSG00000100629","CEP128","ENST00000555265;ENST00000555529;ENST00000556800;ENST00000557377;ENST00000554827;ENST00000554728;ENST00000554502;ENST00000553717;ENST00000556061;ENST00000556981;ENST00000554368;ENST00000557411","GO:0005737(cytoplasm);GO:0005856(cytoskeleton);GO:0000922(spindle pole);GO:0005814(centriole);GO:0005814(centriole)","NA","NA","NA","centrosomal protein 128 [Source:HGNC Symbol;Acc:HGNC:20359]",{"v":0.622065644042553,"d":"0.62"},{"v":0.295069429787234,"d":"0.30"},{"v":2.10820092237649,"d":"2.11"},{"v":1.07601236977527,"d":"1.08"},{"v":0.103212533428742,"d":"0.10"},{"v":0.855392517239441,"d":"0.86"},"up","no"]
["MSTRG.10327","CCDC117","ENST00000249064;ENST00000453543;ENST00000421503;ENST00000432510","GO:0005515(protein binding);GO:0005515(protein binding)","NA","NA","NA","coiled-coil domain containing 117 [Source:HGNC Symbol;Acc:HGNC:26599]",{"v":1.86981316689783,"d":"1.87"},{"v":4.04194527831715,"d":"4.04"},{"v":0.462602296208305,"d":"0.46"},{"v":-1.11215566782352,"d":"-1.11"},{"v":0.103436202315639,"d":"0.10"},{"v":0.855655135424563,"d":"0.86"},"down","no"]
["MSTRG.4866","APBA2","ENST00000411764;MSTRG.4866.4;ENST00000558358;ENST00000558804;ENST00000559814;ENST00000561069;ENST00000382938;ENST00000560283;ENST00000558402","GO:0006810(transport);GO:0015031(protein transport);GO:0008021(synaptic vesicle);GO:0007268(chemical synaptic transmission);GO:0001540(amyloid-beta binding);GO:0005515(protein binding);GO:0007399(nervous system development);GO:0001701(in utero embryonic development);GO:0007626(locomotory behavior);GO:0010468(regulation of gene expression);GO:0035264(multicellular organism growth);GO:0005886(plasma membrane);GO:0005886(plasma membrane)","NA","NA","NA","amyloid beta precursor protein binding family A member 2 [Source:HGNC Symbol;Acc:HGNC:579]",{"v":6.54082197102926,"d":"6.54"},{"v":3.15432652554957,"d":"3.15"},{"v":2.07360332484592,"d":"2.07"},{"v":1.05213993657537,"d":"1.05"},{"v":0.103477442760092,"d":"0.10"},{"v":0.855655135424563,"d":"0.86"},"up","no"]
["MSTRG.8286","CARD8-AS1","ENST00000602172","NA","NA","NA","NA","CARD8 antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:51408]",{"v":6.494086,"d":"6.49"},{"v":13.993055,"d":"13.99"},{"v":0.464093509244407,"d":"0.46"},{"v":-1.10751257459621,"d":"-1.11"},{"v":0.103519320860061,"d":"0.10"},{"v":0.855655135424563,"d":"0.86"},"down","no"]
["ENSG00000081913","PHLPP1","ENST00000262719;ENST00000588953;ENST00000591106;ENST00000588452;ENST00000487409","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0046872(metal ion binding);GO:0016787(hydrolase activity);GO:0003824(catalytic activity);GO:0005886(plasma membrane);GO:0004721(phosphoprotein phosphatase activity);GO:0005515(protein binding);GO:0006915(apoptotic process);GO:0006470(protein dephosphorylation);GO:0005829(cytosol);GO:0042981(regulation of apoptotic process);GO:0031965(nuclear membrane);GO:0051898(negative regulation of protein kinase B signaling);GO:1900744(regulation of p38MAPK cascade);GO:0004722(protein serine/threonine phosphatase activity);GO:0002667(regulation of T cell anergy);GO:0009649(entrainment of circadian clock);GO:0043408(regulation of MAPK cascade);GO:0046328(regulation of JNK cascade);GO:0090036(regulation of protein kinase C signaling);GO:0090036(regulation of protein kinase C signaling)","04151(PI3K-Akt signaling pathway);04151(PI3K-Akt signaling pathway)","K16340","EC:3.1.3.16","PH domain and leucine rich repeat protein phosphatase 1 [Source:HGNC Symbol;Acc:HGNC:20610]",{"v":0.683767513454386,"d":"0.68"},{"v":1.47754079238679,"d":"1.48"},{"v":0.462774034380358,"d":"0.46"},{"v":-1.11162017582139,"d":"-1.11"},{"v":0.103592617810624,"d":"0.10"},{"v":0.855655135424563,"d":"0.86"},"down","no"]
["ENSG00000156475","PPP2R2B","ENST00000394409;ENST00000453001;ENST00000512984;ENST00000394414;ENST00000512011;ENST00000530902;ENST00000512639;ENST00000508545;ENST00000532154;ENST00000394411;ENST00000515880","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005739(mitochondrion);GO:0050790(regulation of catalytic activity);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0006915(apoptotic process);GO:0005741(mitochondrial outer membrane);GO:0019888(protein phosphatase regulator activity);GO:0000159(protein phosphatase type 2A complex);GO:0005829(cytosol);GO:0004722(protein serine/threonine phosphatase activity);GO:0000278(mitotic cell cycle);GO:0032502(developmental process);GO:0070262(peptidyl-serine dephosphorylation);GO:0070262(peptidyl-serine dephosphorylation)","03015(mRNA surveillance pathway);04390(Hippo signaling pathway);04071(Sphingolipid signaling pathway);04151(PI3K-Akt signaling pathway);04152(AMPK signaling pathway);04530(Tight junction);04261(Adrenergic signaling in cardiomyocytes);04728(Dopaminergic synapse);05160(Hepatitis C);05165(Human papillomavirus infection);05142(Chagas disease (American trypanosomiasis));05142(Chagas disease (American trypanosomiasis))","K04354","NA","protein phosphatase 2 regulatory subunit Bbeta [Source:HGNC Symbol;Acc:HGNC:9305]",{"v":0.756059081856732,"d":"0.76"},{"v":0.359842655005301,"d":"0.36"},{"v":2.10108243517043,"d":"2.10"},{"v":1.07113276671276,"d":"1.07"},{"v":0.103628123284064,"d":"0.10"},{"v":0.855655135424563,"d":"0.86"},"up","no"]
["ENSG00000186047","DLEU7","ENST00000443723","NA","NA","NA","NA","deleted in lymphocytic leukemia, 7 [Source:HGNC Symbol;Acc:HGNC:17567]",{"v":0.308890216083151,"d":"0.31"},{"v":0.685481487417943,"d":"0.69"},{"v":0.45061788210601,"d":"0.45"},{"v":-1.15002352895324,"d":"-1.15"},{"v":0.103735737950836,"d":"0.10"},{"v":0.855655135424563,"d":"0.86"},"down","no"]
["ENSG00000269911","FAM226B","ENST00000602508","NA","NA","NA","NA","family with sequence similarity 226 member B (non-protein coding) [Source:HGNC Symbol;Acc:HGNC:31964]",{"v":1.018726,"d":"1.02"},{"v":0.465731,"d":"0.47"},{"v":2.18736996248908,"d":"2.19"},{"v":1.12919725235137,"d":"1.13"},{"v":0.103750276101795,"d":"0.10"},{"v":0.855655135424563,"d":"0.86"},"up","no"]
["ENSG00000132196","HSD17B7","ENST00000485405;ENST00000488656;ENST00000484251;ENST00000494450;ENST00000463037;ENST00000254521;ENST00000367913;ENST00000470195;ENST00000367915","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0006629(lipid metabolic process);GO:0006694(steroid biosynthetic process);GO:0005886(plasma membrane);GO:0000253(3-keto sterol reductase activity);GO:0006695(cholesterol biosynthetic process);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0004303(estradiol 17-beta-dehydrogenase activity);GO:0006703(estrogen biosynthetic process);GO:0006703(estrogen biosynthetic process)","00100(Steroid biosynthesis);00140(Steroid hormone biosynthesis);04913(Ovarian Steroidogenesis);04913(Ovarian Steroidogenesis)","K13373","EC:1.1.1.62;EC:1.1.1.270","hydroxysteroid 17-beta dehydrogenase 7 [Source:HGNC Symbol;Acc:HGNC:5215]",{"v":0.241740215324927,"d":"0.24"},{"v":0.544801290494665,"d":"0.54"},{"v":0.443721811131235,"d":"0.44"},{"v":-1.1722726243583,"d":"-1.17"},{"v":0.103812668398546,"d":"0.10"},{"v":0.855655135424563,"d":"0.86"},"down","no"]
["MSTRG.8378","FPR1","MSTRG.8378.1","NA","NA","NA","NA",null,{"v":6.817557,"d":"6.82"},{"v":14.663311,"d":"14.66"},{"v":0.464939807932874,"d":"0.46"},{"v":-1.10488414085522,"d":"-1.10"},{"v":0.10422853923398,"d":"0.10"},{"v":0.857689207213059,"d":"0.86"},"down","no"]
["MSTRG.12102","GTF2H2","ENST00000521602;ENST00000330280;ENST00000518275;ENST00000523693;ENST00000517900;ENST00000523003;ENST00000521858;ENST00000518898;ENST00000508592;ENST00000521942;ENST00000522654;ENST00000274400","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0016607(nuclear speck);GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0006468(protein phosphorylation);GO:0006281(DNA repair);GO:0006974(cellular response to DNA damage stimulus);GO:0006289(nucleotide-excision repair);GO:0000439(core TFIIH complex);GO:0005515(protein binding);GO:0005654(nucleoplasm);GO:0006366(transcription from RNA polymerase II promoter);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0047485(protein N-terminus binding);GO:0006368(transcription elongation from RNA polymerase II promoter);GO:0006370(7-methylguanosine mRNA capping);GO:0006367(transcription initiation from RNA polymerase II promoter);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0004672(protein kinase activity);GO:0008135(translation factor activity, RNA binding);GO:0006361(transcription initiation from RNA polymerase I promoter);GO:0006362(transcription elongation from RNA polymerase I promoter);GO:0006363(termination of RNA polymerase I transcription);GO:0008094(DNA-dependent ATPase activity);GO:0006283(transcription-coupled nucleotide-excision repair);GO:0005669(transcription factor TFIID complex);GO:0008353(RNA polymerase II carboxy-terminal domain kinase activity);GO:0002031(G-protein coupled receptor internalization);GO:0006293(nucleotide-excision repair, preincision complex stabilization);GO:0006295(nucleotide-excision repair, DNA incision, 3'-to lesion);GO:0006296(nucleotide-excision repair, DNA incision, 5'-to lesion);GO:0033683(nucleotide-excision repair, DNA incision);GO:0070911(global genome nucleotide-excision repair);GO:0000717(nucleotide-excision repair, DNA duplex unwinding);GO:0006294(nucleotide-excision repair, preincision complex assembly);GO:0005675(holo TFIIH complex);GO:0009411(response to UV);GO:0006412(translation);GO:0000438(core TFIIH complex portion of holo TFIIH complex);GO:0000438(core TFIIH complex portion of holo TFIIH complex)","03022(Basal transcription factors);03420(Nucleotide excision repair);05203(Viral carcinogenesis);05203(Viral carcinogenesis)","K03142","NA","general transcription factor IIH subunit 2 [Source:HGNC Symbol;Acc:HGNC:4656]",{"v":0.298991345205164,"d":"0.30"},{"v":0.659900443637621,"d":"0.66"},{"v":0.453085534473974,"d":"0.45"},{"v":-1.14214466379285,"d":"-1.14"},{"v":0.104284830569991,"d":"0.10"},{"v":0.857689207213059,"d":"0.86"},"down","no"]
["MSTRG.3728","TMEM116","ENST00000552839;ENST00000549537;ENST00000550831;ENST00000552374;ENST00000547878;ENST00000552801;ENST00000551297;ENST00000550233;ENST00000437003;ENST00000552800;ENST00000550020;ENST00000546537;ENST00000549425;ENST00000548283;ENST00000355445","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0003674(molecular_function);GO:0008150(biological_process);GO:0005575(cellular_component);GO:0005575(cellular_component)","NA","NA","NA","transmembrane protein 116 [Source:HGNC Symbol;Acc:HGNC:25084]",{"v":0.616913819376643,"d":"0.62"},{"v":0.289545850168982,"d":"0.29"},{"v":2.13062566435197,"d":"2.13"},{"v":1.0912771442131,"d":"1.09"},{"v":0.104376490761101,"d":"0.10"},{"v":0.857689207213059,"d":"0.86"},"up","no"]
["ENSG00000197818","SLC9A8","ENST00000490250;ENST00000417961;ENST00000361573","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0055085(transmembrane transport);GO:0005794(Golgi apparatus);GO:0006811(ion transport);GO:0015297(antiporter activity);GO:0015299(solute:proton antiporter activity);GO:0015385(sodium:proton antiporter activity);GO:0006812(cation transport);GO:0006814(sodium ion transport);GO:0006885(regulation of pH);GO:0035725(sodium ion transmembrane transport);GO:1902600(hydrogen ion transmembrane transport);GO:0000139(Golgi membrane);GO:0051453(regulation of intracellular pH);GO:0015386(potassium:proton antiporter activity);GO:0071805(potassium ion transmembrane transport);GO:0006813(potassium ion transport);GO:0006813(potassium ion transport)","NA","NA","NA","solute carrier family 9 member A8 [Source:HGNC Symbol;Acc:HGNC:20728]",{"v":1.73166951137345,"d":"1.73"},{"v":3.72381386826951,"d":"3.72"},{"v":0.46502579683935,"d":"0.47"},{"v":-1.10461734438735,"d":"-1.10"},{"v":0.104383552408052,"d":"0.10"},{"v":0.857689207213059,"d":"0.86"},"down","no"]
["ENSG00000275764","AC092747.4","ENST00000620519","NA","NA","NA","NA",null,{"v":1.354241,"d":"1.35"},{"v":0.637247,"d":"0.64"},{"v":2.12514299792702,"d":"2.13"},{"v":1.08755992146639,"d":"1.09"},{"v":0.104415576961829,"d":"0.10"},{"v":0.857689207213059,"d":"0.86"},"up","no"]
["MSTRG.9561","SIRPA","ENST00000400068;ENST00000622179;ENST00000358771;ENST00000356025","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0050900(leukocyte migration);GO:0005886(plasma membrane);GO:0070062(extracellular exosome);GO:0017124(SH3 domain binding);GO:0043312(neutrophil degranulation);GO:0070821(tertiary granule membrane);GO:0007155(cell adhesion);GO:0101003(ficolin-1-rich granule membrane);GO:0101003(ficolin-1-rich granule membrane)","04380(Osteoclast differentiation);04380(Osteoclast differentiation)","K06551","NA","signal regulatory protein alpha [Source:HGNC Symbol;Acc:HGNC:9662]",{"v":19.9025558916732,"d":"19.90"},{"v":42.6486650361089,"d":"42.65"},{"v":0.466663045017294,"d":"0.47"},{"v":-1.09954686988491,"d":"-1.10"},{"v":0.104519645375373,"d":"0.10"},{"v":0.857958806823614,"d":"0.86"},"down","no"]
["ENSG00000154640","BTG3","ENST00000339775;ENST00000348354;ENST00000457956;ENST00000496601;ENST00000464058","GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0008285(negative regulation of cell proliferation);GO:0045930(negative regulation of mitotic cell cycle);GO:0045930(negative regulation of mitotic cell cycle)","03018(RNA degradation);03018(RNA degradation)","K14443","NA","BTG anti-proliferation factor 3 [Source:HGNC Symbol;Acc:HGNC:1132]",{"v":0.402904084995664,"d":"0.40"},{"v":0.910654048568951,"d":"0.91"},{"v":0.442433749269339,"d":"0.44"},{"v":-1.1764666549603,"d":"-1.18"},{"v":0.104725558298113,"d":"0.10"},{"v":0.859063469363676,"d":"0.86"},"down","no"]
["MSTRG.4178","SLC7A7","ENST00000397532;ENST00000555702;ENST00000285850;ENST00000555911;ENST00000488800;ENST00000555678;ENST00000554061;ENST00000397529;ENST00000555959;ENST00000555251;ENST00000556287;ENST00000557129;ENST00000554741;ENST00000553874;ENST00000553632;ENST00000556350;ENST00000557629","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005886(plasma membrane);GO:0015171(amino acid transmembrane transporter activity);GO:0003333(amino acid transmembrane transport);GO:1990822(basic amino acid transmembrane transport);GO:0050900(leukocyte migration);GO:1902475(L-alpha-amino acid transmembrane transport);GO:0016323(basolateral plasma membrane);GO:0006865(amino acid transport);GO:0005887(integral component of plasma membrane);GO:0015297(antiporter activity);GO:0006461(protein complex assembly);GO:0006520(cellular amino acid metabolic process);GO:0015179(L-amino acid transmembrane transporter activity);GO:0015807(L-amino acid transport);GO:0015174(basic amino acid transmembrane transporter activity);GO:0000821(regulation of arginine metabolic process);GO:0000821(regulation of arginine metabolic process)","04974(Protein digestion and absorption);04974(Protein digestion and absorption)","K13867","NA","solute carrier family 7 member 7 [Source:HGNC Symbol;Acc:HGNC:11065]",{"v":7.54582007854219,"d":"7.55"},{"v":16.1870190512571,"d":"16.19"},{"v":0.466164897603934,"d":"0.47"},{"v":-1.10108772182205,"d":"-1.10"},{"v":0.104829901355764,"d":"0.10"},{"v":0.859195810570585,"d":"0.86"},"down","no"]
["ENSG00000139131","YARS2","ENST00000324868;ENST00000551673;ENST00000548490","GO:0003723(RNA binding);GO:0005737(cytoplasm);GO:0006412(translation);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0005739(mitochondrion);GO:0016874(ligase activity);GO:0005515(protein binding);GO:0016604(nuclear body);GO:0005759(mitochondrial matrix);GO:0004812(aminoacyl-tRNA ligase activity);GO:0006418(tRNA aminoacylation for protein translation);GO:0004831(tyrosine-tRNA ligase activity);GO:0006437(tyrosyl-tRNA aminoacylation);GO:0005829(cytosol);GO:0042803(protein homodimerization activity);GO:0000049(tRNA binding);GO:0043039(tRNA aminoacylation);GO:0072545(tyrosine binding);GO:0070184(mitochondrial tyrosyl-tRNA aminoacylation);GO:0070184(mitochondrial tyrosyl-tRNA aminoacylation)","00970(Aminoacyl-tRNA biosynthesis);00970(Aminoacyl-tRNA biosynthesis)","K01866","EC:6.1.1.1","tyrosyl-tRNA synthetase 2 [Source:HGNC Symbol;Acc:HGNC:24249]",{"v":0.934647324349442,"d":"0.93"},{"v":2.0419297732342,"d":"2.04"},{"v":0.457727457917938,"d":"0.46"},{"v":-1.12743925670919,"d":"-1.13"},{"v":0.104884391424909,"d":"0.10"},{"v":0.859195810570585,"d":"0.86"},"down","no"]
["ENSG00000174807","CD248","ENST00000311330","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0030246(carbohydrate binding);GO:0005509(calcium ion binding);GO:0005578(proteinaceous extracellular matrix);GO:0003674(molecular_function);GO:0008150(biological_process);GO:0070062(extracellular exosome);GO:0050840(extracellular matrix binding);GO:0008284(positive regulation of cell proliferation);GO:0016477(cell migration);GO:0048535(lymph node development);GO:0060033(anatomical structure regression);GO:2000353(positive regulation of endothelial cell apoptotic process);GO:0005737(cytoplasm)","NA","NA","NA","CD248 molecule [Source:HGNC Symbol;Acc:HGNC:18219]",{"v":4.840458,"d":"4.84"},{"v":2.330063,"d":"2.33"},{"v":2.07739361553743,"d":"2.08"},{"v":1.05477459768567,"d":"1.05"},{"v":0.105066143342025,"d":"0.11"},{"v":0.860099590839335,"d":"0.86"},"up","no"]
["MSTRG.13616","URGCP;MRPS24;URGCP-MRPS24","ENST00000453200;ENST00000426198;ENST00000317534;ENST00000603700;ENST00000443736;ENST00000477768;ENST00000483330;ENST00000467410;ENST00000402306;ENST00000336086;ENST00000414932;ENST00000418740;ENST00000467084;ENST00000497914;ENST00000474376","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005525(GTP binding);GO:0005829(cytosol);GO:0007049(cell cycle);GO:0003723(RNA binding);GO:0030529(intracellular ribonucleoprotein complex);GO:0005840(ribosome);GO:0005739(mitochondrion);GO:0003735(structural constituent of ribosome);GO:0032543(mitochondrial translation);GO:0008150(biological_process);GO:0005743(mitochondrial inner membrane);GO:0006412(translation);GO:0070125(mitochondrial translational elongation);GO:0070126(mitochondrial translational termination);GO:0005763(mitochondrial small ribosomal subunit);GO:0005761(mitochondrial ribosome);GO:0007049(cell cycle)","NA","NA","NA","upregulator of cell proliferation [Source:HGNC Symbol;Acc:HGNC:30890];mitochondrial ribosomal protein S24 [Source:HGNC Symbol;Acc:HGNC:14510];URGCP-MRPS24 readthrough [Source:HGNC Symbol;Acc:HGNC:49188]",{"v":1.43396574777363,"d":"1.43"},{"v":0.688675428229436,"d":"0.69"},{"v":2.08220838002063,"d":"2.08"},{"v":1.05811445565892,"d":"1.06"},{"v":0.105263021660096,"d":"0.11"},{"v":0.861125887792713,"d":"0.86"},"up","no"]
["ENSG00000049246","PER3","ENST00000613533;ENST00000377541;ENST00000614998;ENST00000361923;ENST00000494684;ENST00000602883;ENST00000463106","GO:0032922(circadian regulation of gene expression);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0005515(protein binding);GO:0048511(rhythmic process);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0050821(protein stabilization);GO:0045187(regulation of circadian sleep/wake cycle, sleep);GO:0019900(kinase binding);GO:0031625(ubiquitin protein ligase binding);GO:0007623(circadian rhythm);GO:0007623(circadian rhythm)","04710(Circadian rhythm);04713(Circadian entrainment);05168(Herpes simplex infection);05168(Herpes simplex infection)","K21945","NA","period circadian clock 3 [Source:HGNC Symbol;Acc:HGNC:8847]",{"v":0.325127048524509,"d":"0.33"},{"v":0.153245547474997,"d":"0.15"},{"v":2.12160845050037,"d":"2.12"},{"v":1.08515842691999,"d":"1.09"},{"v":0.105472644221379,"d":"0.11"},{"v":0.861331471190335,"d":"0.86"},"up","no"]
["ENSG00000160336","ZNF761","ENST00000432094;ENST00000454407;ENST00000610928","GO:0003676(nucleic acid binding);GO:0046872(metal ion binding);GO:0006355(regulation of transcription, DNA-templated);GO:0005622(intracellular);GO:0005622(intracellular)","NA","NA","NA","zinc finger protein 761 [Source:HGNC Symbol;Acc:HGNC:23179]",{"v":0.453719837293169,"d":"0.45"},{"v":0.208779942299533,"d":"0.21"},{"v":2.1731964876311,"d":"2.17"},{"v":1.11981862040768,"d":"1.12"},{"v":0.105498736475833,"d":"0.11"},{"v":0.861331471190335,"d":"0.86"},"up","no"]
["ENSG00000164494","PDSS2","ENST00000369037;ENST00000369031","GO:0005829(cytosol);GO:0016740(transferase activity);GO:0005739(mitochondrion);GO:0008299(isoprenoid biosynthetic process);GO:0005759(mitochondrial matrix);GO:0006744(ubiquinone biosynthetic process);GO:1990234(transferase complex);GO:0046982(protein heterodimerization activity);GO:0000010(trans-hexaprenyltranstransferase activity);GO:0050347(trans-octaprenyltranstransferase activity);GO:0050878(regulation of body fluid levels);GO:0051290(protein heterotetramerization);GO:0051290(protein heterotetramerization)","00900(Terpenoid backbone biosynthesis);00900(Terpenoid backbone biosynthesis)","K12505","EC:2.5.1.91","decaprenyl diphosphate synthase subunit 2 [Source:HGNC Symbol;Acc:HGNC:23041]",{"v":1.58256142435048,"d":"1.58"},{"v":0.757647224656138,"d":"0.76"},{"v":2.08878403147155,"d":"2.09"},{"v":1.06266333355769,"d":"1.06"},{"v":0.105502733765632,"d":"0.11"},{"v":0.861331471190335,"d":"0.86"},"up","no"]
["ENSG00000156345","CDK20","ENST00000459720;ENST00000604175;ENST00000336654;ENST00000605591;ENST00000375871;ENST00000375883;ENST00000603475;ENST00000325303;ENST00000486228","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0005654(nucleoplasm);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0051301(cell division);GO:0042995(cell projection);GO:0007049(cell cycle);GO:0007275(multicellular organism development);GO:0005515(protein binding);GO:0005929(cilium);GO:0004693(cyclin-dependent protein serine/threonine kinase activity);GO:0019912(cyclin-dependent protein kinase activating kinase activity);GO:1904031(positive regulation of cyclin-dependent protein kinase activity);GO:1904031(positive regulation of cyclin-dependent protein kinase activity)","NA","NA","NA","cyclin dependent kinase 20 [Source:HGNC Symbol;Acc:HGNC:21420]",{"v":0.423328995983936,"d":"0.42"},{"v":0.196679915488039,"d":"0.20"},{"v":2.15237531973457,"d":"2.15"},{"v":1.1059296693014,"d":"1.11"},{"v":0.105925773446546,"d":"0.11"},{"v":0.863635569498726,"d":"0.86"},"up","no"]
["ENSG00000197363","ZNF517","ENST00000531720;ENST00000526178;ENST00000525105;ENST00000528012;ENST00000530879;ENST00000533965;ENST00000359971","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0005622(intracellular);GO:0005622(intracellular)","NA","NA","NA","zinc finger protein 517 [Source:HGNC Symbol;Acc:HGNC:27984]",{"v":0.505456857573474,"d":"0.51"},{"v":0.240238759231349,"d":"0.24"},{"v":2.10397714003643,"d":"2.10"},{"v":1.07311902966099,"d":"1.07"},{"v":0.106065372080246,"d":"0.11"},{"v":0.863635569498726,"d":"0.86"},"up","no"]
["MSTRG.2074","BET1L","ENST00000382762;ENST00000410108;ENST00000479463;ENST00000325147;ENST00000486280","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0015031(protein transport);GO:0005829(cytosol);GO:0005794(Golgi apparatus);GO:0000139(Golgi membrane);GO:0061025(membrane fusion);GO:0006888(ER to Golgi vesicle-mediated transport);GO:0005484(SNAP receptor activity);GO:0042147(retrograde transport, endosome to Golgi);GO:0031201(SNARE complex);GO:0005768(endosome);GO:2000156(regulation of retrograde vesicle-mediated transport, Golgi to ER);GO:2000156(regulation of retrograde vesicle-mediated transport, Golgi to ER)","04130(SNARE interactions in vesicular transport);04130(SNARE interactions in vesicular transport)","K08504","NA","Bet1 golgi vesicular membrane trafficking protein like [Source:HGNC Symbol;Acc:HGNC:19348]",{"v":10.1931895224922,"d":"10.19"},{"v":4.9402030188728,"d":"4.94"},{"v":2.06331389288086,"d":"2.06"},{"v":1.04496331577339,"d":"1.04"},{"v":0.106080402037947,"d":"0.11"},{"v":0.863635569498726,"d":"0.86"},"up","no"]
["MSTRG.5817","HIRIP3","ENST00000279392;ENST00000563053;ENST00000568880;ENST00000565996;ENST00000564026;ENST00000563680","GO:0005634(nucleus);GO:0005730(nucleolus);GO:0005515(protein binding);GO:0006333(chromatin assembly or disassembly);GO:0006333(chromatin assembly or disassembly)","NA","NA","NA","HIRA interacting protein 3 [Source:HGNC Symbol;Acc:HGNC:4917]",{"v":3.08295064309336,"d":"3.08"},{"v":1.49170804019334,"d":"1.49"},{"v":2.06672523042363,"d":"2.07"},{"v":1.04734659628384,"d":"1.05"},{"v":0.106102220112648,"d":"0.11"},{"v":0.863635569498726,"d":"0.86"},"up","no"]
["ENSG00000263753","LINC00667","ENST00000582008;ENST00000580082;ENST00000580684;ENST00000581471;ENST00000582363;ENST00000577439","NA","NA","NA","NA","long intergenic non-protein coding RNA 667 [Source:HGNC Symbol;Acc:HGNC:27906]",{"v":1.07961002510523,"d":"1.08"},{"v":0.515006757817198,"d":"0.52"},{"v":2.09630263820429,"d":"2.10"},{"v":1.06784701034793,"d":"1.07"},{"v":0.106143551142511,"d":"0.11"},{"v":0.863635569498726,"d":"0.86"},"up","no"]
["MSTRG.1627","RAB18","ENST00000535776;ENST00000621805;ENST00000356940;ENST00000375802;ENST00000490236;ENST00000484281;ENST00000465772;ENST00000423465","GO:0006810(transport);GO:0016020(membrane);GO:0015031(protein transport);GO:0005525(GTP binding);GO:0000166(nucleotide binding);GO:0003924(GTPase activity);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0007275(multicellular organism development);GO:0005789(endoplasmic reticulum membrane);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0001654(eye development);GO:0061024(membrane organization);GO:0005794(Golgi apparatus);GO:0043312(neutrophil degranulation);GO:0019003(GDP binding);GO:0030667(secretory granule membrane);GO:0007420(brain development);GO:0005622(intracellular);GO:0071786(endoplasmic reticulum tubular network organization);GO:0007264(small GTPase mediated signal transduction);GO:0071782(endoplasmic reticulum tubular network);GO:0034389(lipid particle organization);GO:1902593(single-organism nuclear import);GO:1902593(single-organism nuclear import)","NA","NA","NA","RAB18, member RAS oncogene family [Source:HGNC Symbol;Acc:HGNC:14244]",{"v":3.90796839434356,"d":"3.91"},{"v":8.35853289860196,"d":"8.36"},{"v":0.467542383544031,"d":"0.47"},{"v":-1.09683094110167,"d":"-1.10"},{"v":0.106356132791012,"d":"0.11"},{"v":0.864780925772699,"d":"0.86"},"down","no"]
["MSTRG.8612","PPP1CB;SPDYA","ENST00000395366;ENST00000358506;ENST00000467226;MSTRG.8612.2;ENST00000418910;ENST00000441461;ENST00000449210;ENST00000420282;ENST00000462832;ENST00000464273;ENST00000334056;ENST00000455580;ENST00000427786","GO:0046872(metal ion binding);GO:0016787(hydrolase activity);GO:0004721(phosphoprotein phosphatase activity);GO:0006470(protein dephosphorylation);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0051301(cell division);GO:0005515(protein binding);GO:0007049(cell cycle);GO:0048511(rhythmic process);GO:0005975(carbohydrate metabolic process);GO:0005654(nucleoplasm);GO:0005730(nucleolus);GO:0005925(focal adhesion);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0019901(protein kinase binding);GO:0000784(nuclear chromosome, telomeric region);GO:0000086(G2/M transition of mitotic cell cycle);GO:0032922(circadian regulation of gene expression);GO:0030155(regulation of cell adhesion);GO:0072357(PTW/PP1 phosphatase complex);GO:0042752(regulation of circadian rhythm);GO:0043153(entrainment of circadian clock by photoperiod);GO:0016791(phosphatase activity);GO:0005977(glycogen metabolic process);GO:0017018(myosin phosphatase activity);GO:0050115(myosin-light-chain-phosphatase activity);GO:0004722(protein serine/threonine phosphatase activity);GO:0005979(regulation of glycogen biosynthetic process);GO:0005981(regulation of glycogen catabolic process);GO:0000164(protein phosphatase type 1 complex);GO:0042587(glycogen granule);GO:0006974(cellular response to DNA damage stimulus);GO:0007275(multicellular organism development);GO:0008284(positive regulation of cell proliferation);GO:0000082(G1/S transition of mitotic cell cycle);GO:0007140(male meiotic nuclear division);GO:0045737(positive regulation of cyclin-dependent protein serine/threonine kinase activity);GO:0042587(glycogen granule)","03015(mRNA surveillance pathway);04390(Hippo signaling pathway);04024(cAMP signaling pathway);04022(cGMP - PKG signaling pathway);04114(Oocyte meiosis);04218(Cellular senescence);04510(Focal adhesion);04810(Regulation of actin cytoskeleton);04611(Platelet activation);04910(Insulin signaling pathway);04921(Oxytocin signaling pathway);04261(Adrenergic signaling in cardiomyocytes);04270(Vascular smooth muscle contraction);04728(Dopaminergic synapse);04720(Long-term potentiation);04750(Inflammatory mediator regulation of TRP channels);05205(Proteoglycans in cancer);05031(Amphetamine addiction);05034(Alcoholism);04931(Insulin resistance);05168(Herpes simplex infection);04914(Progesterone-mediated oocyte maturation);05168(Herpes simplex infection)","K06269;K08694","EC:3.1.3.16","protein phosphatase 1 catalytic subunit beta [Source:HGNC Symbol;Acc:HGNC:9282];speedy/RINGO cell cycle regulator family member A [Source:HGNC Symbol;Acc:HGNC:30613]",{"v":5.38444208732779,"d":"5.38"},{"v":11.5026107079586,"d":"11.50"},{"v":0.468106086873158,"d":"0.47"},{"v":-1.09509257007542,"d":"-1.10"},{"v":0.106431426121847,"d":"0.11"},{"v":0.864809199297761,"d":"0.86"},"down","no"]
["ENSG00000154027","AK5","ENST00000354567;ENST00000344720;ENST00000478255;ENST00000524494;ENST00000466393;ENST00000531672;ENST00000530826;ENST00000317704","GO:0005737(cytoplasm);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0005829(cytosol);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0006139(nucleobase-containing compound metabolic process);GO:0005815(microtubule organizing center);GO:0019205(nucleobase-containing compound kinase activity);GO:0004550(nucleoside diphosphate kinase activity);GO:0046034(ATP metabolic process);GO:0004017(adenylate kinase activity);GO:0019206(nucleoside kinase activity);GO:0015949(nucleobase-containing small molecule interconversion);GO:0006165(nucleoside diphosphate phosphorylation);GO:0009142(nucleoside triphosphate biosynthetic process);GO:0009220(pyrimidine ribonucleotide biosynthetic process);GO:0006172(ADP biosynthetic process);GO:0006173(dADP biosynthetic process);GO:0006173(dADP biosynthetic process)","00230(Purine metabolism);00730(Thiamine metabolism);00730(Thiamine metabolism)","K00939","EC:2.7.4.3","adenylate kinase 5 [Source:HGNC Symbol;Acc:HGNC:365]",{"v":1.34047920942333,"d":"1.34"},{"v":0.645101642578407,"d":"0.65"},{"v":2.07793488800551,"d":"2.08"},{"v":1.05515044816739,"d":"1.06"},{"v":0.106751644664233,"d":"0.11"},{"v":0.866826234016647,"d":"0.87"},"up","no"]
["MSTRG.11566","KLF3-AS1","ENST00000610668;ENST00000507091;ENST00000436901;ENST00000440181","NA","NA","NA","NA","KLF3 antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:25796]",{"v":0.303821550310559,"d":"0.30"},{"v":0.138804241407867,"d":"0.14"},{"v":2.1888491823373,"d":"2.19"},{"v":1.13017255233067,"d":"1.13"},{"v":0.106927024824175,"d":"0.11"},{"v":0.867600628481978,"d":"0.87"},"up","no"]
["ENSG00000162599","NFIA","ENST00000407417;ENST00000371187;ENST00000371184;ENST00000482020;ENST00000403491;ENST00000357977","GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0005622(intracellular);GO:0030054(cell junction);GO:0006260(DNA replication);GO:0006366(transcription from RNA polymerase II promoter);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0008134(transcription factor binding);GO:0001077(transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0019079(viral genome replication);GO:0003682(chromatin binding);GO:0060074(synapse maturation);GO:0072189(ureter development);GO:0072189(ureter development)","NA","NA","NA","nuclear factor I A [Source:HGNC Symbol;Acc:HGNC:7784]",{"v":0.260071687729948,"d":"0.26"},{"v":0.122739950147167,"d":"0.12"},{"v":2.11888376537646,"d":"2.12"},{"v":1.08330444862827,"d":"1.08"},{"v":0.106991108893517,"d":"0.11"},{"v":0.867600628481978,"d":"0.87"},"up","no"]
["ENSG00000115364","MRPL19","ENST00000476622;ENST00000409374;ENST00000493686;ENST00000358788;ENST00000393909","GO:0005634(nucleus);GO:0005739(mitochondrion);GO:0030529(intracellular ribonucleoprotein complex);GO:0005622(intracellular);GO:0003735(structural constituent of ribosome);GO:0006412(translation);GO:0005840(ribosome);GO:0031965(nuclear membrane);GO:0005743(mitochondrial inner membrane);GO:0070125(mitochondrial translational elongation);GO:0070126(mitochondrial translational termination);GO:0005762(mitochondrial large ribosomal subunit);GO:0005762(mitochondrial large ribosomal subunit)","03010(Ribosome);03010(Ribosome)","K02884","NA","mitochondrial ribosomal protein L19 [Source:HGNC Symbol;Acc:HGNC:14052]",{"v":0.429546716583351,"d":"0.43"},{"v":0.933718434253423,"d":"0.93"},{"v":0.460038809158572,"d":"0.46"},{"v":-1.12017252193754,"d":"-1.12"},{"v":0.107194101224895,"d":"0.11"},{"v":0.868661754340635,"d":"0.87"},"down","no"]
["ENSG00000227159","DDX11L16","ENST00000507418","NA","NA","NA","NA","DEAD/H-box helicase 11 like 16 [Source:HGNC Symbol;Acc:HGNC:37115]",{"v":0.618845,"d":"0.62"},{"v":1.387693,"d":"1.39"},{"v":0.44595238283972,"d":"0.45"},{"v":-1.16503842220473,"d":"-1.17"},{"v":0.107313988135875,"d":"0.11"},{"v":0.869048449988034,"d":"0.87"},"down","no"]
["ENSG00000170396","ZNF804A","ENST00000302277","GO:0003676(nucleic acid binding);GO:0046872(metal ion binding)","NA","NA","NA","zinc finger protein 804A [Source:HGNC Symbol;Acc:HGNC:21711]",{"v":0.203208687686408,"d":"0.20"},{"v":0.449782390285471,"d":"0.45"},{"v":0.451793338457368,"d":"0.45"},{"v":-1.14626509605847,"d":"-1.15"},{"v":0.107574734365289,"d":"0.11"},{"v":0.869084837111801,"d":"0.87"},"down","no"]
["MSTRG.14061","AC245088.2","ENST00000634605","NA","NA","NA","NA",null,{"v":3.883852,"d":"3.88"},{"v":1.766805,"d":"1.77"},{"v":2.19823466653083,"d":"2.20"},{"v":1.13634540547233,"d":"1.14"},{"v":0.107590452733182,"d":"0.11"},{"v":0.869084837111801,"d":"0.87"},"up","no"]
["ENSG00000162664","ZNF326","ENST00000370447;ENST00000340281;ENST00000394583;ENST00000361911","GO:0005634(nucleus);GO:0003723(RNA binding);GO:0006397(mRNA processing);GO:0008380(RNA splicing);GO:0043231(intracellular membrane-bounded organelle);GO:0046872(metal ion binding);GO:0005654(nucleoplasm);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0005681(spliceosomal complex);GO:0043484(regulation of RNA splicing);GO:0016363(nuclear matrix);GO:0000993(RNA polymerase II core binding);GO:0032784(regulation of DNA-templated transcription, elongation);GO:0044609(DBIRD complex);GO:0044609(DBIRD complex)","NA","NA","NA","zinc finger protein 326 [Source:HGNC Symbol;Acc:HGNC:14104]",{"v":1.00819500300437,"d":"1.01"},{"v":0.486685770393299,"d":"0.49"},{"v":2.07155225062288,"d":"2.07"},{"v":1.05071220977589,"d":"1.05"},{"v":0.10759257397859,"d":"0.11"},{"v":0.869084837111801,"d":"0.87"},"up","no"]
["ENSG00000129932","DOHH","ENST00000427575","GO:0046872(metal ion binding);GO:0004497(monooxygenase activity);GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0008612(peptidyl-lysine modification to peptidyl-hypusine);GO:0005515(protein binding);GO:0005575(cellular_component);GO:0005829(cytosol);GO:0019135(deoxyhypusine monooxygenase activity)","NA","NA","NA","deoxyhypusine hydroxylase [Source:HGNC Symbol;Acc:HGNC:28662]",{"v":2.405257,"d":"2.41"},{"v":1.155235,"d":"1.16"},{"v":2.08204997251641,"d":"2.08"},{"v":1.05800469603234,"d":"1.06"},{"v":0.107607165930385,"d":"0.11"},{"v":0.869084837111801,"d":"0.87"},"up","no"]
["MSTRG.872","FMO5","ENST00000533174;ENST00000441068;ENST00000578284;ENST00000527849;ENST00000254090;ENST00000619062;ENST00000478432","GO:0004497(monooxygenase activity);GO:0004499(N,N-dimethylaniline monooxygenase activity);GO:0016491(oxidoreductase activity);GO:0050660(flavin adenine dinucleotide binding);GO:0050661(NADP binding);GO:0055114(oxidation-reduction process);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005783(endoplasmic reticulum);GO:0005829(cytosol);GO:0005789(endoplasmic reticulum membrane);GO:0008150(biological_process);GO:0043231(intracellular membrane-bounded organelle);GO:0031090(organelle membrane);GO:0031090(organelle membrane)","00982(Drug metabolism - cytochrome P450);00982(Drug metabolism - cytochrome P450)","K00485","EC:1.14.13.8","flavin containing monooxygenase 5 [Source:HGNC Symbol;Acc:HGNC:3773]",{"v":0.199870401269629,"d":"0.20"},{"v":0.44586312429001,"d":"0.45"},{"v":0.448277487822976,"d":"0.45"},{"v":-1.1575360447998,"d":"-1.16"},{"v":0.10771894315279,"d":"0.11"},{"v":0.869404499628618,"d":"0.87"},"down","no"]
["ENSG00000113971","NPHP3","ENST00000474871;ENST00000337331;ENST00000493732;ENST00000471145;ENST00000490993;ENST00000476742;ENST00000515289;ENST00000469232;ENST00000465756;ENST00000383282","GO:0042995(cell projection);GO:0005515(protein binding);GO:0016055(Wnt signaling pathway);GO:0060271(cilium assembly);GO:0005929(cilium);GO:0005829(cytosol);GO:0090090(negative regulation of canonical Wnt signaling pathway);GO:0001947(heart looping);GO:0007368(determination of left/right symmetry);GO:0001822(kidney development);GO:0030324(lung development);GO:0035469(determination of pancreatic left/right asymmetry);GO:0071910(determination of liver left/right asymmetry);GO:0045494(photoreceptor cell maintenance);GO:0048496(maintenance of animal organ identity);GO:0003283(atrial septum development);GO:0060993(kidney morphogenesis);GO:0060027(convergent extension involved in gastrulation);GO:0060287(epithelial cilium movement involved in determination of left/right asymmetry);GO:0071908(determination of intestine left/right asymmetry);GO:0071909(determination of stomach left/right asymmetry);GO:0072189(ureter development);GO:2000095(regulation of Wnt signaling pathway, planar cell polarity pathway);GO:2000167(regulation of planar cell polarity pathway involved in neural tube closure);GO:2000167(regulation of planar cell polarity pathway involved in neural tube closure)","NA","NA","NA","nephrocystin 3 [Source:HGNC Symbol;Acc:HGNC:7907]",{"v":0.654524359138233,"d":"0.65"},{"v":0.313935392536852,"d":"0.31"},{"v":2.08490146284287,"d":"2.08"},{"v":1.05997920025159,"d":"1.06"},{"v":0.107904583682085,"d":"0.11"},{"v":0.869490386344553,"d":"0.87"},"up","no"]
["ENSG00000281162","AC005035.1","ENST00000625702;ENST00000627215;ENST00000627337","NA","NA","NA","NA",null,{"v":0.393321064566519,"d":"0.39"},{"v":0.862571593855767,"d":"0.86"},{"v":0.455986572440139,"d":"0.46"},{"v":-1.13293675330271,"d":"-1.13"},{"v":0.107948942922996,"d":"0.11"},{"v":0.869490386344553,"d":"0.87"},"down","no"]
["MSTRG.14786","DCAF10","ENST00000242323;ENST00000377724;ENST00000478453;ENST00000461549;ENST00000483167","GO:0016567(protein ubiquitination);GO:0005654(nucleoplasm);GO:0043687(post-translational protein modification);GO:0080008(Cul4-RING E3 ubiquitin ligase complex);GO:0080008(Cul4-RING E3 ubiquitin ligase complex)","NA","NA","NA","DDB1 and CUL4 associated factor 10 [Source:HGNC Symbol;Acc:HGNC:23686]",{"v":0.305752376000942,"d":"0.31"},{"v":0.665174352213848,"d":"0.67"},{"v":0.459657494284514,"d":"0.46"},{"v":-1.12136883230061,"d":"-1.12"},{"v":0.108011209498947,"d":"0.11"},{"v":0.869490386344553,"d":"0.87"},"down","no"]
["ENSG00000140044","JDP2","ENST00000267569;ENST00000419727;ENST00000559060;ENST00000558068;ENST00000437176;ENST00000435893;ENST00000559773","GO:0005634(nucleus);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0005515(protein binding);GO:0031063(regulation of histone deacetylation);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:0001078(transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0003682(chromatin binding);GO:0003690(double-stranded DNA binding);GO:0046982(protein heterodimerization activity);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0031065(positive regulation of histone deacetylation);GO:0045599(negative regulation of fat cell differentiation);GO:0045599(negative regulation of fat cell differentiation)","NA","NA","NA","Jun dimerization protein 2 [Source:HGNC Symbol;Acc:HGNC:17546]",{"v":0.619704107457899,"d":"0.62"},{"v":1.33271374546913,"d":"1.33"},{"v":0.464994159146874,"d":"0.46"},{"v":-1.10471550043608,"d":"-1.10"},{"v":0.108056103709948,"d":"0.11"},{"v":0.869490386344553,"d":"0.87"},"down","no"]
["ENSG00000170448","NFXL1","ENST00000507131;ENST00000502448;ENST00000464756;ENST00000329043;ENST00000511452;ENST00000508115;ENST00000507489;ENST00000381538","GO:0005634(nucleus);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0006355(regulation of transcription, DNA-templated);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0000977(RNA polymerase II regulatory region sequence-specific DNA binding);GO:0006366(transcription from RNA polymerase II promoter);GO:0001078(transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0001078(transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding)","NA","NA","NA","nuclear transcription factor, X-box binding like 1 [Source:HGNC Symbol;Acc:HGNC:18726]",{"v":0.679064349464764,"d":"0.68"},{"v":1.46188308809099,"d":"1.46"},{"v":0.464513445019413,"d":"0.46"},{"v":-1.106207739868,"d":"-1.11"},{"v":0.108131411996616,"d":"0.11"},{"v":0.869490386344553,"d":"0.87"},"down","no"]
["MSTRG.9808","B4GALT5","ENST00000371711","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0046872(metal ion binding);GO:0016740(transferase activity);GO:0016757(transferase activity, transferring glycosyl groups);GO:0005794(Golgi apparatus);GO:0005975(carbohydrate metabolic process);GO:0006486(protein glycosylation);GO:0032580(Golgi cisterna membrane);GO:0070062(extracellular exosome);GO:0000139(Golgi membrane);GO:0003831(beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity);GO:0008378(galactosyltransferase activity);GO:0016266(O-glycan processing);GO:0018146(keratan sulfate biosynthetic process)","00512(Mucin type O-glycan biosynthesis)","K09905","EC:2.4.1.-","beta-1,4-galactosyltransferase 5 [Source:HGNC Symbol;Acc:HGNC:928]",{"v":8.944883,"d":"8.94"},{"v":19.021233,"d":"19.02"},{"v":0.470257790333571,"d":"0.47"},{"v":-1.08847625112291,"d":"-1.09"},{"v":0.108243008103925,"d":"0.11"},{"v":0.869490386344553,"d":"0.87"},"down","no"]
["MSTRG.14546","TRIB1","ENST00000311922;ENST00000521778;ENST00000519576;ENST00000520847","GO:0005737(cytoplasm);GO:0043433(negative regulation of sequence-specific DNA binding transcription factor activity);GO:0005634(nucleus);GO:0048662(negative regulation of smooth muscle cell proliferation);GO:0005515(protein binding);GO:0004860(protein kinase inhibitor activity);GO:0032496(response to lipopolysaccharide);GO:0006469(negative regulation of protein kinase activity);GO:0032436(positive regulation of proteasomal ubiquitin-dependent protein catabolic process);GO:0043405(regulation of MAP kinase activity);GO:0031625(ubiquitin protein ligase binding);GO:0008134(transcription factor binding);GO:0014912(negative regulation of smooth muscle cell migration);GO:0031434(mitogen-activated protein kinase kinase binding);GO:0055106(ubiquitin-protein transferase regulator activity);GO:0007254(JNK cascade);GO:0031665(negative regulation of lipopolysaccharide-mediated signaling pathway);GO:0045645(positive regulation of eosinophil differentiation);GO:0045651(positive regulation of macrophage differentiation);GO:0045659(negative regulation of neutrophil differentiation);GO:0004672(protein kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0006468(protein phosphorylation)","NA","NA","NA","tribbles pseudokinase 1 [Source:HGNC Symbol;Acc:HGNC:16891]",{"v":2.76549447196713,"d":"2.77"},{"v":5.89758457950701,"d":"5.90"},{"v":0.468919849250946,"d":"0.47"},{"v":-1.09258674564349,"d":"-1.09"},{"v":0.108247953181103,"d":"0.11"},{"v":0.869490386344553,"d":"0.87"},"down","no"]
["MSTRG.9295","ASNSD1","ENST00000260952;ENST00000607690;ENST00000420250;ENST00000605941;ENST00000607829;ENST00000425590;ENST00000607535;ENST00000606910","GO:0004066(asparagine synthase (glutamine-hydrolyzing) activity);GO:0006529(asparagine biosynthetic process);GO:0003674(molecular_function);GO:0008150(biological_process);GO:0005575(cellular_component);GO:0008652(cellular amino acid biosynthetic process);GO:0006541(glutamine metabolic process);GO:0042803(protein homodimerization activity);GO:0042803(protein homodimerization activity)","NA","NA","NA","asparagine synthetase domain containing 1 [Source:HGNC Symbol;Acc:HGNC:24910]",{"v":3.90421096365815,"d":"3.90"},{"v":8.34101397763578,"d":"8.34"},{"v":0.468073902540657,"d":"0.47"},{"v":-1.09519176505382,"d":"-1.10"},{"v":0.108307223012525,"d":"0.11"},{"v":0.869490386344553,"d":"0.87"},"down","no"]
["ENSG00000163898","LIPH","ENST00000296252;ENST00000429510","GO:0016020(membrane);GO:0016787(hydrolase activity);GO:0006629(lipid metabolic process);GO:0016042(lipid catabolic process);GO:0005886(plasma membrane);GO:0005576(extracellular region);GO:0052689(carboxylic ester hydrolase activity);GO:0005615(extracellular space);GO:0008201(heparin binding);GO:0006654(phosphatidic acid biosynthetic process);GO:0004620(phospholipase activity);GO:0004620(phospholipase activity)","NA","NA","NA","lipase H [Source:HGNC Symbol;Acc:HGNC:18483]",{"v":0.461575723435226,"d":"0.46"},{"v":0.213766730713246,"d":"0.21"},{"v":2.15924957964764,"d":"2.16"},{"v":1.11053000876557,"d":"1.11"},{"v":0.1086281186717,"d":"0.11"},{"v":0.871485546332183,"d":"0.87"},"up","no"]
["ENSG00000133256","PDE6B","ENST00000471824;ENST00000255622;ENST00000460119;ENST00000496514;ENST00000461490","GO:0016020(membrane);GO:0046872(metal ion binding);GO:0016787(hydrolase activity);GO:0007165(signal transduction);GO:0008081(phosphoric diester hydrolase activity);GO:0004114(3',5'-cyclic-nucleotide phosphodiesterase activity);GO:0050896(response to stimulus);GO:0005886(plasma membrane);GO:0007601(visual perception);GO:0022400(regulation of rhodopsin mediated signaling pathway);GO:0007223(Wnt signaling pathway, calcium modulating pathway);GO:0097381(photoreceptor disc membrane);GO:0047555(3',5'-cyclic-GMP phosphodiesterase activity);GO:0051480(regulation of cytosolic calcium ion concentration);GO:0007603(phototransduction, visible light);GO:0016056(rhodopsin mediated signaling pathway);GO:0046037(GMP metabolic process);GO:0009583(detection of light stimulus);GO:0060041(retina development in camera-type eye);GO:0001750(photoreceptor outer segment);GO:0016021(integral component of membrane);GO:0016021(integral component of membrane)","00230(Purine metabolism);04744(Phototransduction);04744(Phototransduction)","K13756","EC:3.1.4.35","phosphodiesterase 6B [Source:HGNC Symbol;Acc:HGNC:8786]",{"v":0.494119361974046,"d":"0.49"},{"v":0.232356264648053,"d":"0.23"},{"v":2.12655924178538,"d":"2.13"},{"v":1.08852104618845,"d":"1.09"},{"v":0.108926100032529,"d":"0.11"},{"v":0.873294338609665,"d":"0.87"},"up","no"]
["MSTRG.2320","CAT","ENST00000241052;ENST00000525707;ENST00000528104;ENST00000534710;ENST00000530343","GO:0016020(membrane);GO:0043231(intracellular membrane-bounded organelle);GO:0046872(metal ion binding);GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0042803(protein homodimerization activity);GO:0020037(heme binding);GO:0098869(cellular oxidant detoxification);GO:0005925(focal adhesion);GO:0005576(extracellular region);GO:0005777(peroxisome);GO:0005778(peroxisomal membrane);GO:0004601(peroxidase activity);GO:0006979(response to oxidative stress);GO:0005739(mitochondrion);GO:0070062(extracellular exosome);GO:0042744(hydrogen peroxide catabolic process);GO:0005102(receptor binding);GO:0005782(peroxisomal matrix);GO:0043312(neutrophil degranulation);GO:0043066(negative regulation of apoptotic process);GO:0019899(enzyme binding);GO:0034774(secretory granule lumen);GO:1904813(ficolin-1-rich granule lumen);GO:0051289(protein homotetramerization);GO:0034599(cellular response to oxidative stress);GO:0051781(positive regulation of cell division);GO:0001649(osteoblast differentiation);GO:0051262(protein tetramerization);GO:0050661(NADP binding);GO:0016209(antioxidant activity);GO:0000302(response to reactive oxygen species);GO:0004046(aminoacylase activity);GO:0004096(catalase activity);GO:0016684(oxidoreductase activity, acting on peroxide as acceptor);GO:0001657(ureteric bud development);GO:0001666(response to hypoxia);GO:0001822(kidney development);GO:0006641(triglyceride metabolic process);GO:0007568(aging);GO:0008203(cholesterol metabolic process);GO:0009060(aerobic respiration);GO:0009314(response to radiation);GO:0009411(response to UV);GO:0009636(response to toxic substance);GO:0009642(response to light intensity);GO:0009650(UV protection);GO:0010193(response to ozone);GO:0010288(response to lead ion);GO:0014068(positive regulation of phosphatidylinositol 3-kinase signaling);GO:0014823(response to activity);GO:0014854(response to inactivity);GO:0020027(hemoglobin metabolic process);GO:0032088(negative regulation of NF-kappaB transcription factor activity);GO:0032355(response to estradiol);GO:0032868(response to insulin);GO:0033189(response to vitamin A);GO:0033197(response to vitamin E);GO:0033591(response to L-ascorbic acid);GO:0042493(response to drug);GO:0042542(response to hydrogen peroxide);GO:0045471(response to ethanol);GO:0046686(response to cadmium ion);GO:0051092(positive regulation of NF-kappaB transcription factor activity);GO:0055093(response to hyperoxia);GO:0070542(response to fatty acid);GO:0071363(cellular response to growth factor stimulus);GO:0080184(response to phenylpropanoid);GO:0005615(extracellular space);GO:0005758(mitochondrial intermembrane space);GO:0005764(lysosome);GO:0005783(endoplasmic reticulum);GO:0005794(Golgi apparatus);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0005886(plasma membrane)","00630(Glyoxylate and dicarboxylate metabolism);00380(Tryptophan metabolism);04068(FoxO signaling pathway);04146(Peroxisome);04211(Longevity regulating pathway - mammal);04213(Longevity regulating pathway - multiple species);05014(Amyotrophic lateral sclerosis (ALS));05014(Amyotrophic lateral sclerosis (ALS))","K03781","EC:1.11.1.6","catalase [Source:HGNC Symbol;Acc:HGNC:1516]",{"v":17.1219274962653,"d":"17.12"},{"v":36.3146242939946,"d":"36.31"},{"v":0.471488493386307,"d":"0.47"},{"v":-1.0847055323371,"d":"-1.08"},{"v":0.109438024307306,"d":"0.11"},{"v":0.876814829480091,"d":"0.88"},"down","no"]
["MSTRG.753","STXBP3","ENST00000370008;ENST00000485167;ENST00000495245;ENST00000472099","GO:0006810(transport);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0015031(protein transport);GO:0016192(vesicle-mediated transport);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0006904(vesicle docking involved in exocytosis);GO:0005515(protein binding);GO:0070062(extracellular exosome);GO:0019905(syntaxin binding);GO:0042581(specific granule);GO:0017075(syntaxin-1 binding);GO:0006887(exocytosis);GO:0007420(brain development);GO:0015758(glucose transport);GO:0022615(protein to membrane docking);GO:0030073(insulin secretion);GO:0032868(response to insulin);GO:0043312(neutrophil degranulation);GO:0045955(negative regulation of calcium ion-dependent exocytosis);GO:0051291(protein heterooligomerization);GO:0070527(platelet aggregation);GO:0016323(basolateral plasma membrane);GO:0016324(apical plasma membrane);GO:0031091(platelet alpha granule);GO:0070820(tertiary granule);GO:0070820(tertiary granule)","NA","NA","NA","syntaxin binding protein 3 [Source:HGNC Symbol;Acc:HGNC:11446]",{"v":2.13233254334181,"d":"2.13"},{"v":4.53973564817642,"d":"4.54"},{"v":0.469704121251719,"d":"0.47"},{"v":-1.09017584282172,"d":"-1.09"},{"v":0.109533847197399,"d":"0.11"},{"v":0.876999061137687,"d":"0.88"},"down","no"]
["MSTRG.6845","EZH1","MSTRG.6845.4;ENST00000585893;ENST00000415827;ENST00000590783;ENST00000428826;ENST00000585455;ENST00000585550;ENST00000590078;ENST00000586714;ENST00000586935;ENST00000587179;MSTRG.6845.1;ENST00000586867;ENST00000588239;ENST00000591330;ENST00000586103;ENST00000589846;ENST00000590082","GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0008168(methyltransferase activity);GO:0016740(transferase activity);GO:0032259(methylation);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0016569(covalent chromatin modification);GO:0018024(histone-lysine N-methyltransferase activity);GO:0070734(histone H3-K27 methylation);GO:0035098(ESC/E(Z) complex);GO:0009653(anatomical structure morphogenesis);GO:0003682(chromatin binding);GO:0021766(hippocampus development);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0045944(positive regulation of transcription from RNA polymerase II promoter)","00310(Lysine degradation);00310(Lysine degradation)","K17451","EC:2.1.1.43","enhancer of zeste 1 polycomb repressive complex 2 subunit [Source:HGNC Symbol;Acc:HGNC:3526]",{"v":3.20005379649423,"d":"3.20"},{"v":6.79883969887416,"d":"6.80"},{"v":0.470676459252913,"d":"0.47"},{"v":-1.08719239603137,"d":"-1.09"},{"v":0.109805455163693,"d":"0.11"},{"v":0.878127673170185,"d":"0.88"},"down","no"]
["MSTRG.8577","IFT172","ENST00000507184;ENST00000463613;ENST00000260570;ENST00000480892;ENST00000475476;ENST00000476693;ENST00000476264;ENST00000494163;ENST00000420854;ENST00000475909;ENST00000443889;ENST00000511842","GO:0042995(cell projection);GO:0007275(multicellular organism development);GO:0035735(intraciliary transport involved in cilium assembly);GO:0060271(cilium assembly);GO:0005929(cilium);GO:0030992(intraciliary transport particle B);GO:0097542(ciliary tip);GO:0036064(ciliary basal body);GO:1903561(extracellular vesicle);GO:0005930(axoneme);GO:0001841(neural tube formation);GO:0001843(neural tube closure);GO:0001947(heart looping);GO:0007219(Notch signaling pathway);GO:0007224(smoothened signaling pathway);GO:0007368(determination of left/right symmetry);GO:0007420(brain development);GO:0007507(heart development);GO:0008544(epidermis development);GO:0008589(regulation of smoothened signaling pathway);GO:0009953(dorsal/ventral pattern formation);GO:0016485(protein processing);GO:0021522(spinal cord motor neuron differentiation);GO:0021915(neural tube development);GO:0031122(cytoplasmic microtubule organization);GO:0045880(positive regulation of smoothened signaling pathway);GO:0050680(negative regulation of epithelial cell proliferation);GO:0060021(palate development);GO:0060173(limb development);GO:0060348(bone development);GO:0061525(hindgut development);GO:0070986(left/right axis specification);GO:1905515(non-motile cilium assembly);GO:0097225(sperm midpiece);GO:0097228(sperm principal piece);GO:0097598(sperm cytoplasmic droplet);GO:0097598(sperm cytoplasmic droplet)","NA","NA","NA","intraflagellar transport 172 [Source:HGNC Symbol;Acc:HGNC:30391]",{"v":0.801527551124866,"d":"0.80"},{"v":0.385240606594453,"d":"0.39"},{"v":2.08058947422602,"d":"2.08"},{"v":1.05699233176001,"d":"1.06"},{"v":0.109895013503745,"d":"0.11"},{"v":0.878127673170185,"d":"0.88"},"up","no"]
["ENSG00000184005","ST6GALNAC3","ENST00000328299;ENST00000621530;ENST00000464140","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005654(nucleoplasm);GO:0016740(transferase activity);GO:0008373(sialyltransferase activity);GO:0016757(transferase activity, transferring glycosyl groups);GO:0006486(protein glycosylation);GO:0097503(sialylation);GO:0005794(Golgi apparatus);GO:0000139(Golgi membrane);GO:0009100(glycoprotein metabolic process);GO:0009311(oligosaccharide metabolic process);GO:0018279(protein N-linked glycosylation via asparagine);GO:0001665(alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity);GO:0006677(glycosylceramide metabolic process);GO:0006687(glycosphingolipid metabolic process);GO:0006687(glycosphingolipid metabolic process)","00604(Glycosphingolipid biosynthesis - ganglio series);00604(Glycosphingolipid biosynthesis - ganglio series)","K03373","EC:2.4.99.-","ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 3 [Source:HGNC Symbol;Acc:HGNC:19343]",{"v":0.151570553682465,"d":"0.15"},{"v":0.330903148542214,"d":"0.33"},{"v":0.458051107552785,"d":"0.46"},{"v":-1.1264195173088,"d":"-1.13"},{"v":0.11008757766226,"d":"0.11"},{"v":0.878127673170185,"d":"0.88"},"down","no"]
["MSTRG.11337","TNIK","ENST00000284483;ENST00000470834;ENST00000341852;ENST00000488470;ENST00000484051;ENST00000460047;ENST00000436636;ENST00000465393;ENST00000459881;ENST00000357327;ENST00000475336;ENST00000496492;ENST00000464785;ENST00000487846;ENST00000468757","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0016055(Wnt signaling pathway);GO:0007399(nervous system development);GO:0000185(activation of MAPKKK activity);GO:0005768(endosome);GO:0070062(extracellular exosome);GO:0001934(positive regulation of protein phosphorylation);GO:0007010(cytoskeleton organization);GO:0055037(recycling endosome);GO:0016324(apical plasma membrane);GO:0042981(regulation of apoptotic process);GO:0046777(protein autophosphorylation);GO:0008349(MAP kinase kinase kinase kinase activity);GO:0007346(regulation of mitotic cell cycle);GO:0035556(intracellular signal transduction);GO:0030033(microvillus assembly);GO:0031532(actin cytoskeleton reorganization);GO:0048814(regulation of dendrite morphogenesis);GO:0072659(protein localization to plasma membrane);GO:0007256(activation of JNKK activity);GO:0007256(activation of JNKK activity)","NA","NA","NA","TRAF2 and NCK interacting kinase [Source:HGNC Symbol;Acc:HGNC:30765]",{"v":4.63203012155344,"d":"4.63"},{"v":2.26149580546756,"d":"2.26"},{"v":2.04821521682892,"d":"2.05"},{"v":1.03436731491736,"d":"1.03"},{"v":0.110186380073846,"d":"0.11"},{"v":0.878127673170185,"d":"0.88"},"up","no"]
["MSTRG.9944","FP236383.1","MSTRG.9944.1","NA","NA","NA","NA",null,{"v":141.095718,"d":"141.10"},{"v":69.074936,"d":"69.07"},{"v":2.04264710429844,"d":"2.04"},{"v":1.03043997996203,"d":"1.03"},{"v":0.110186998579728,"d":"0.11"},{"v":0.878127673170185,"d":"0.88"},"up","no"]
["MSTRG.1519","AKR1C3","ENST00000380554;ENST00000603312;ENST00000603484;ENST00000605322;ENST00000439082;ENST00000480697;ENST00000480822","GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0008202(steroid metabolic process);GO:0007186(G-protein coupled receptor signaling pathway);GO:0042572(retinol metabolic process);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0008584(male gonad development);GO:0009267(cellular response to starvation);GO:2000379(positive regulation of reactive oxygen species metabolic process);GO:0008284(positive regulation of cell proliferation);GO:0001523(retinoid metabolic process);GO:0006693(prostaglandin metabolic process);GO:0019371(cyclooxygenase pathway);GO:0051897(positive regulation of protein kinase B signaling);GO:0070293(renal absorption);GO:0004745(retinol dehydrogenase activity);GO:0047035(testosterone dehydrogenase (NAD+) activity);GO:0030216(keratinocyte differentiation);GO:0005622(intracellular);GO:0010942(positive regulation of cell death);GO:0071277(cellular response to calcium ion);GO:0004033(aldo-keto reductase (NADP) activity);GO:0044597(daunorubicin metabolic process);GO:0044598(doxorubicin metabolic process);GO:0001758(retinal dehydrogenase activity);GO:0045550(geranylgeranyl reductase activity);GO:0047718(indanol dehydrogenase activity);GO:0016488(farnesol catabolic process);GO:0016655(oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor);GO:0052650(NADP-retinol dehydrogenase activity);GO:0000060(protein import into nucleus, translocation);GO:0071276(cellular response to cadmium ion);GO:0042448(progesterone metabolic process);GO:0034614(cellular response to reactive oxygen species);GO:2000353(positive regulation of endothelial cell apoptotic process);GO:0004032(alditol:NADP+ 1-oxidoreductase activity);GO:0047023(androsterone dehydrogenase activity);GO:0071395(cellular response to jasmonic acid stimulus);GO:0061370(testosterone biosynthetic process);GO:0047045(testosterone 17-beta-dehydrogenase (NADP+) activity);GO:0018636(phenanthrene 9,10-monooxygenase activity);GO:0035410(dihydrotestosterone 17-beta-dehydrogenase activity);GO:0036130(prostaglandin H2 endoperoxidase reductase activity);GO:0036131(prostaglandin D2 11-ketoreductase activity);GO:0045703(ketoreductase activity);GO:0047017(prostaglandin-F synthase activity);GO:0047020(15-hydroxyprostaglandin-D dehydrogenase (NADP+) activity);GO:0047086(ketosteroid monooxygenase activity);GO:0047115(trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity);GO:0047787(delta4-3-oxosteroid 5beta-reductase activity);GO:0007584(response to nutrient);GO:0042574(retinal metabolic process);GO:0044259(multicellular organismal macromolecule metabolic process);GO:0048385(regulation of retinoic acid receptor signaling pathway);GO:0071379(cellular response to prostaglandin stimulus);GO:0071384(cellular response to corticosteroid stimulus);GO:0071799(cellular response to prostaglandin D stimulus);GO:1900053(negative regulation of retinoic acid biosynthetic process);GO:2000224(regulation of testosterone biosynthetic process);GO:2000224(regulation of testosterone biosynthetic process)","00140(Steroid hormone biosynthesis);00590(Arachidonic acid metabolism);00790(Folate biosynthesis);04913(Ovarian Steroidogenesis);04913(Ovarian Steroidogenesis)","K04119","EC:1.1.1.51;EC:1.1.1.188","aldo-keto reductase family 1 member C3 [Source:HGNC Symbol;Acc:HGNC:386]",{"v":0.734723424977935,"d":"0.73"},{"v":0.346205855251545,"d":"0.35"},{"v":2.12221547912326,"d":"2.12"},{"v":1.08557114771351,"d":"1.09"},{"v":0.110196545957565,"d":"0.11"},{"v":0.878127673170185,"d":"0.88"},"up","no"]
["ENSG00000115159","GPD2","ENST00000310454;ENST00000438166;ENST00000464846;ENST00000492005;ENST00000496190;ENST00000409125;ENST00000495851","GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0006072(glycerol-3-phosphate metabolic process);GO:0009331(glycerol-3-phosphate dehydrogenase complex);GO:0004368(glycerol-3-phosphate dehydrogenase activity);GO:0052590(sn-glycerol-3-phosphate:ubiquinone oxidoreductase activity);GO:0052591(sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity);GO:0046872(metal ion binding);GO:0005509(calcium ion binding);GO:0005739(mitochondrion);GO:0005743(mitochondrial inner membrane);GO:0019563(glycerol catabolic process);GO:0006094(gluconeogenesis);GO:0006127(glycerophosphate shuttle);GO:0035264(multicellular organism growth);GO:0043010(camera-type eye development);GO:0043010(camera-type eye development)","00564(Glycerophospholipid metabolism);00564(Glycerophospholipid metabolism)","K00111","EC:1.1.5.3","glycerol-3-phosphate dehydrogenase 2 [Source:HGNC Symbol;Acc:HGNC:4456]",{"v":0.669783013976241,"d":"0.67"},{"v":1.43336018644305,"d":"1.43"},{"v":0.467281720471348,"d":"0.47"},{"v":-1.09763549316752,"d":"-1.10"},{"v":0.110210639099077,"d":"0.11"},{"v":0.878127673170185,"d":"0.88"},"down","no"]
["MSTRG.2487","SNHG1","ENST00000540725;ENST00000544550;ENST00000538266;ENST00000545308;ENST00000537965;ENST00000541578;ENST00000541615;ENST00000538654;ENST00000537869;ENST00000545920;ENST00000535076;ENST00000544983;ENST00000539921;ENST00000545688;ENST00000535689;ENST00000540904;ENST00000537024;ENST00000541416","NA","NA","NA","NA","small nucleolar RNA host gene 1 [Source:HGNC Symbol;Acc:HGNC:32688]",{"v":2.82098768618143,"d":"2.82"},{"v":1.36815396334388,"d":"1.37"},{"v":2.06189344310834,"d":"2.06"},{"v":1.04396977738526,"d":"1.04"},{"v":0.110258183178319,"d":"0.11"},{"v":0.878127673170185,"d":"0.88"},"up","no"]
["MSTRG.5961","DOK4","ENST00000340099;ENST00000566936;ENST00000569548","GO:0005622(intracellular);GO:0005158(insulin receptor binding);GO:0005057(signal transducer activity, downstream of receptor);GO:0000165(MAPK cascade);GO:0007169(transmembrane receptor protein tyrosine kinase signaling pathway);GO:0007399(nervous system development);GO:0005515(protein binding);GO:0005829(cytosol);GO:0007411(axon guidance);GO:0007411(axon guidance)","NA","NA","NA","docking protein 4 [Source:HGNC Symbol;Acc:HGNC:19868]",{"v":0.300742082289056,"d":"0.30"},{"v":0.656216127401838,"d":"0.66"},{"v":0.458297304395408,"d":"0.46"},{"v":-1.12564429476714,"d":"-1.13"},{"v":0.110597298886055,"d":"0.11"},{"v":0.880246314068651,"d":"0.88"},"down","no"]
["ENSG00000187801","ZFP69B","ENST00000469416;ENST00000411995;ENST00000361584;ENST00000484445","GO:0005634(nucleus);GO:0006355(regulation of transcription, DNA-templated);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0003676(nucleic acid binding);GO:0046872(metal ion binding);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0005622(intracellular);GO:0005515(protein binding);GO:0005515(protein binding)","NA","NA","NA","ZFP69 zinc finger protein B [Source:HGNC Symbol;Acc:HGNC:28053]",{"v":1.03170350041911,"d":"1.03"},{"v":0.485845385582565,"d":"0.49"},{"v":2.12352227896951,"d":"2.12"},{"v":1.08645924482387,"d":"1.09"},{"v":0.110802306377356,"d":"0.11"},{"v":0.881295491014614,"d":"0.88"},"up","no"]
["MSTRG.7068","DHX40","ENST00000251241;ENST00000578204;ENST00000538926;ENST00000580218;ENST00000583439;ENST00000584385;ENST00000577549;ENST00000425628","GO:0003676(nucleic acid binding);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0016787(hydrolase activity);GO:0004386(helicase activity);GO:0005737(cytoplasm);GO:0003723(RNA binding);GO:0004004(ATP-dependent RNA helicase activity);GO:0000398(mRNA splicing, via spliceosome);GO:0005681(spliceosomal complex);GO:0006810(transport);GO:0006810(transport)","NA","NA","NA","DEAH-box helicase 40 [Source:HGNC Symbol;Acc:HGNC:18018]",{"v":1.25490724195993,"d":"1.25"},{"v":2.66965017225122,"d":"2.67"},{"v":0.470064300934872,"d":"0.47"},{"v":-1.0890699757679,"d":"-1.09"},{"v":0.11100853111469,"d":"0.11"},{"v":0.881979719027407,"d":"0.88"},"down","no"]
["MSTRG.8230","VASP","ENST00000245932;MSTRG.8230.4;ENST00000588482;MSTRG.8230.9;MSTRG.8230.6;ENST00000590459;ENST00000588463;ENST00000588273;MSTRG.8230.5;ENST00000586619;ENST00000587444;MSTRG.8230.10;ENST00000590603;MSTRG.8230.1","GO:0008154(actin polymerization or depolymerization);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005829(cytosol);GO:0003779(actin binding);GO:0005886(plasma membrane);GO:0005925(focal adhesion);GO:0017124(SH3 domain binding);GO:0001843(neural tube closure);GO:0007411(axon guidance);GO:0030036(actin cytoskeleton organization);GO:0051289(protein homotetramerization);GO:0005856(cytoskeleton);GO:0030027(lamellipodium);GO:0030175(filopodium);GO:0042995(cell projection);GO:0005515(protein binding);GO:0030054(cell junction);GO:0005923(bicellular tight junction);GO:0045296(cadherin binding);GO:0070062(extracellular exosome);GO:0015629(actin cytoskeleton);GO:0030838(positive regulation of actin filament polymerization);GO:0031527(filopodium membrane);GO:0031258(lamellipodium membrane);GO:0034329(cell junction assembly);GO:0005522(profilin binding);GO:0005522(profilin binding)","04015(Rap1 signaling pathway);04022(cGMP - PKG signaling pathway);04510(Focal adhesion);04530(Tight junction);04611(Platelet activation);04666(Fc gamma R-mediated phagocytosis);04670(Leukocyte transendothelial migration);04670(Leukocyte transendothelial migration)","K06274","NA","vasodilator stimulated phosphoprotein [Source:HGNC Symbol;Acc:HGNC:12652]",{"v":26.1921776387147,"d":"26.19"},{"v":55.3495789130094,"d":"55.35"},{"v":0.473213674848003,"d":"0.47"},{"v":-1.07943632985223,"d":"-1.08"},{"v":0.111066320062784,"d":"0.11"},{"v":0.881979719027407,"d":"0.88"},"down","no"]
["ENSG00000173517","PEAK1","ENST00000312493;ENST00000567337;ENST00000558305;ENST00000569692;ENST00000560626","GO:0005737(cytoplasm);GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0004713(protein tyrosine kinase activity);GO:0018108(peptidyl-tyrosine phosphorylation);GO:0005856(cytoskeleton);GO:0004715(non-membrane spanning protein tyrosine kinase activity);GO:0030054(cell junction);GO:0005925(focal adhesion);GO:0005515(protein binding);GO:0016477(cell migration);GO:0046777(protein autophosphorylation);GO:0015629(actin cytoskeleton);GO:0034446(substrate adhesion-dependent cell spreading);GO:0034446(substrate adhesion-dependent cell spreading)","NA","NA","NA","pseudopodium enriched atypical kinase 1 [Source:HGNC Symbol;Acc:HGNC:29431]",{"v":0.298832348494873,"d":"0.30"},{"v":0.145328051604367,"d":"0.15"},{"v":2.05626061311547,"d":"2.06"},{"v":1.04002312514553,"d":"1.04"},{"v":0.111131320355733,"d":"0.11"},{"v":0.881979719027407,"d":"0.88"},"up","no"]
["ENSG00000182463","TSHZ2","ENST00000371497","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0007275(multicellular organism development);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0003682(chromatin binding);GO:0010468(regulation of gene expression);GO:0005515(protein binding);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0001078(transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding)","NA","NA","NA","teashirt zinc finger homeobox 2 [Source:HGNC Symbol;Acc:HGNC:13010]",{"v":0.415608569668548,"d":"0.42"},{"v":0.201111170097766,"d":"0.20"},{"v":2.06656134249783,"d":"2.07"},{"v":1.04723218839376,"d":"1.05"},{"v":0.111181299907292,"d":"0.11"},{"v":0.881979719027407,"d":"0.88"},"up","no"]
["MSTRG.5037","CASC4","ENST00000345795;ENST00000299957;ENST00000559222;ENST00000559037;ENST00000558847;ENST00000558735;ENST00000559550;ENST00000429162;ENST00000557945","GO:0005794(Golgi apparatus);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016021(integral component of membrane)","NA","NA","NA","cancer susceptibility 4 [Source:HGNC Symbol;Acc:HGNC:24892]",{"v":3.86311192052762,"d":"3.86"},{"v":8.18171947831822,"d":"8.18"},{"v":0.472163819691566,"d":"0.47"},{"v":-1.08264059790223,"d":"-1.08"},{"v":0.111482604293227,"d":"0.11"},{"v":0.88378770302768,"d":"0.88"},"down","no"]
["MSTRG.2085","LRRC56","ENST00000270115","NA","NA","NA","NA","leucine rich repeat containing 56 [Source:HGNC Symbol;Acc:HGNC:25430]",{"v":0.566,"d":"0.57"},{"v":0.261725,"d":"0.26"},{"v":2.16257522208425,"d":"2.16"},{"v":1.1127503157045,"d":"1.11"},{"v":0.111715843628473,"d":"0.11"},{"v":0.885054071693467,"d":"0.89"},"up","no"]
["ENSG00000066933","MYO9A","ENST00000356056;ENST00000568781;ENST00000563648;ENST00000569314;ENST00000568042;ENST00000561618;ENST00000563542;ENST00000565528;ENST00000444904;ENST00000566885;ENST00000564571;ENST00000567560;ENST00000564699","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0035556(intracellular signal transduction);GO:0007165(signal transduction);GO:0003774(motor activity);GO:0016459(myosin complex);GO:0003779(actin binding);GO:0005096(GTPase activator activity);GO:0043547(positive regulation of GTPase activity);GO:0005515(protein binding);GO:0005829(cytosol);GO:0051056(regulation of small GTPase mediated signal transduction);GO:0007601(visual perception);GO:0016461(unconventional myosin complex);GO:0005622(intracellular);GO:0005622(intracellular)","NA","NA","NA","myosin IXA [Source:HGNC Symbol;Acc:HGNC:7608]",{"v":0.8608452153755,"d":"0.86"},{"v":0.420977235619414,"d":"0.42"},{"v":2.04487355262542,"d":"2.04"},{"v":1.03201163502993,"d":"1.03"},{"v":0.111869551691803,"d":"0.11"},{"v":0.885657423122058,"d":"0.89"},"up","no"]
["ENSG00000163406","SLC15A2","ENST00000489711;ENST00000469013;ENST00000469422;ENST00000465060;ENST00000489957","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0015031(protein transport);GO:0005215(transporter activity);GO:0015293(symporter activity);GO:0055085(transmembrane transport);GO:0005886(plasma membrane);GO:0015992(proton transport);GO:0005515(protein binding);GO:0070062(extracellular exosome);GO:0015833(peptide transport);GO:0005887(integral component of plasma membrane);GO:0015198(oligopeptide transporter activity);GO:0006857(oligopeptide transport);GO:0006811(ion transport);GO:0015893(drug transport);GO:0015333(peptide:proton symporter activity);GO:0015333(peptide:proton symporter activity)","NA","NA","NA","solute carrier family 15 member 2 [Source:HGNC Symbol;Acc:HGNC:10921]",{"v":0.253151207085346,"d":"0.25"},{"v":0.118205712077295,"d":"0.12"},{"v":2.14161568537238,"d":"2.14"},{"v":1.09869961054915,"d":"1.10"},{"v":0.111971804964097,"d":"0.11"},{"v":0.885657423122058,"d":"0.89"},"up","no"]
["MSTRG.12545","CREBRF","ENST00000296953;ENST00000523161;ENST00000522692;ENST00000520420;ENST00000520464;ENST00000517882","GO:0006810(transport);GO:0005634(nucleus);GO:0006355(regulation of transcription, DNA-templated);GO:0006366(transcription from RNA polymerase II promoter);GO:0006351(transcription, DNA-templated);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0005515(protein binding);GO:0006986(response to unfolded protein);GO:0005654(nucleoplasm);GO:0001228(transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0000977(RNA polymerase II regulatory region sequence-specific DNA binding);GO:0030968(endoplasmic reticulum unfolded protein response);GO:0042711(maternal behavior);GO:1900170(negative regulation of glucocorticoid mediated signaling pathway);GO:1902213(positive regulation of prolactin signaling pathway);GO:0016604(nuclear body);GO:0016604(nuclear body)","NA","NA","NA","CREB3 regulatory factor [Source:HGNC Symbol;Acc:HGNC:24050]",{"v":2.31915620668126,"d":"2.32"},{"v":4.89688665223384,"d":"4.90"},{"v":0.473598098421028,"d":"0.47"},{"v":-1.0782648065811,"d":"-1.08"},{"v":0.112111796434231,"d":"0.11"},{"v":0.885657423122058,"d":"0.89"},"down","no"]
["MSTRG.8379","AC018755.2;SIGLEC14;SIGLEC5","ENST00000429354;ENST00000599649;ENST00000360844;MSTRG.8379.7;MSTRG.8379.1;ENST00000533866;ENST00000534261","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0030246(carbohydrate binding);GO:0007155(cell adhesion);GO:0005886(plasma membrane);GO:0045087(innate immune response);GO:0043312(neutrophil degranulation);GO:0070821(tertiary granule membrane);GO:0101003(ficolin-1-rich granule membrane);GO:0005515(protein binding);GO:0030667(secretory granule membrane);GO:0101003(ficolin-1-rich granule membrane)","NA","NA","NA","sialic acid binding Ig like lectin 14 [Source:HGNC Symbol;Acc:HGNC:32926];sialic acid binding Ig like lectin 5 [Source:HGNC Symbol;Acc:HGNC:10874]",{"v":11.3719965344765,"d":"11.37"},{"v":23.9815630027076,"d":"23.98"},{"v":0.474197471332146,"d":"0.47"},{"v":-1.07644012524817,"d":"-1.08"},{"v":0.112184060960432,"d":"0.11"},{"v":0.885657423122058,"d":"0.89"},"down","no"]
["ENSG00000256683","ZNF350","ENST00000243644;ENST00000593596;ENST00000601430;ENST00000594929;ENST00000597788;ENST00000598254;ENST00000600703;ENST00000597555","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0005654(nucleoplasm);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0005622(intracellular);GO:0005515(protein binding);GO:0016604(nuclear body);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0045892(negative regulation of transcription, DNA-templated);GO:0016363(nuclear matrix);GO:0001227(transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding);GO:0017053(transcriptional repressor complex);GO:0001162(RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding);GO:0001162(RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding)","NA","NA","NA","zinc finger protein 350 [Source:HGNC Symbol;Acc:HGNC:16656]",{"v":1.45305810376735,"d":"1.45"},{"v":0.704733143643974,"d":"0.70"},{"v":2.06185577742804,"d":"2.06"},{"v":1.04394342268362,"d":"1.04"},{"v":0.112198555439244,"d":"0.11"},{"v":0.885657423122058,"d":"0.89"},"up","no"]
["ENSG00000162337","LRP5","ENST00000294304;ENST00000529481;ENST00000529993","GO:0008284(positive regulation of cell proliferation);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0045600(positive regulation of fat cell differentiation);GO:0042632(cholesterol homeostasis);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0060070(canonical Wnt signaling pathway);GO:0005783(endoplasmic reticulum);GO:0005515(protein binding);GO:0007275(multicellular organism development);GO:0016055(Wnt signaling pathway);GO:0042813(Wnt-activated receptor activity);GO:0005886(plasma membrane);GO:0006897(endocytosis);GO:0017147(Wnt-protein binding);GO:0045893(positive regulation of transcription, DNA-templated);GO:1904886(beta-catenin destruction complex disassembly);GO:0043235(receptor complex);GO:0060042(retina morphogenesis in camera-type eye);GO:0071936(coreceptor activity involved in Wnt signaling pathway);GO:1904928(coreceptor activity involved in canonical Wnt signaling pathway);GO:0001702(gastrulation with mouth forming second);GO:0001944(vasculature development);GO:0002053(positive regulation of mesenchymal cell proliferation);GO:0002076(osteoblast development);GO:0006007(glucose catabolic process);GO:0008203(cholesterol metabolic process);GO:0008217(regulation of blood pressure);GO:0009314(response to radiation);GO:0009952(anterior/posterior pattern specification);GO:0033690(positive regulation of osteoblast proliferation);GO:0035019(somatic stem cell population maintenance);GO:0035108(limb morphogenesis);GO:0035426(extracellular matrix-cell signaling);GO:0042074(cell migration involved in gastrulation);GO:0042733(embryonic digit morphogenesis);GO:0042981(regulation of apoptotic process);GO:0043434(response to peptide hormone);GO:0044332(Wnt signaling pathway involved in dorsal/ventral axis specification);GO:0045668(negative regulation of osteoblast differentiation);GO:0045840(positive regulation of mitotic nuclear division);GO:0046849(bone remodeling);GO:0046850(regulation of bone remodeling);GO:0048539(bone marrow development);GO:0051091(positive regulation of sequence-specific DNA binding transcription factor activity);GO:0060033(anatomical structure regression);GO:0060348(bone development);GO:0060349(bone morphogenesis);GO:0060444(branching involved in mammary gland duct morphogenesis);GO:0060603(mammary gland duct morphogenesis);GO:0060612(adipose tissue development);GO:0060764(cell-cell signaling involved in mammary gland development);GO:0060828(regulation of canonical Wnt signaling pathway);GO:0061178(regulation of insulin secretion involved in cellular response to glucose stimulus);GO:0061299(retina vasculature morphogenesis in camera-type eye);GO:0061304(retinal blood vessel morphogenesis);GO:0071901(negative regulation of protein serine/threonine kinase activity);GO:1902262(apoptotic process involved in blood vessel morphogenesis);GO:0005739(mitochondrion);GO:1990851(Wnt-Frizzled-LRP5/6 complex);GO:1990909(Wnt signalosome);GO:1990909(Wnt signalosome)","04310(Wnt signaling pathway);04150(mTOR signaling pathway);05200(Pathways in cancer);05225(Hepatocellular carcinoma);05226(Gastric cancer);05224(Breast cancer);05224(Breast cancer)","K03068","NA","LDL receptor related protein 5 [Source:HGNC Symbol;Acc:HGNC:6697]",{"v":0.430623268007787,"d":"0.43"},{"v":0.208710809863725,"d":"0.21"},{"v":2.06325330388472,"d":"2.06"},{"v":1.04492095056275,"d":"1.04"},{"v":0.112233285806698,"d":"0.11"},{"v":0.885657423122058,"d":"0.89"},"up","no"]
["MSTRG.7354","SECTM1","ENST00000269389;ENST00000580437;ENST00000583093;ENST00000582563;ENST00000582290;ENST00000581691;ENST00000581864;ENST00000581954","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005886(plasma membrane);GO:0004871(signal transducer activity);GO:0005576(extracellular region);GO:0006955(immune response);GO:0005125(cytokine activity);GO:0007165(signal transduction);GO:0070062(extracellular exosome);GO:0043123(positive regulation of I-kappaB kinase/NF-kappaB signaling);GO:0005794(Golgi apparatus);GO:0005615(extracellular space);GO:0007498(mesoderm development);GO:0007498(mesoderm development)","NA","NA","NA","secreted and transmembrane 1 [Source:HGNC Symbol;Acc:HGNC:10707]",{"v":18.3696973981763,"d":"18.37"},{"v":38.7634011583924,"d":"38.76"},{"v":0.47389281768943,"d":"0.47"},{"v":-1.07736729920987,"d":"-1.08"},{"v":0.112377035643705,"d":"0.11"},{"v":0.8856800917789,"d":"0.89"},"down","no"]
["MSTRG.9383","KLF7","ENST00000309446;ENST00000426163;ENST00000458272;MSTRG.9383.1;ENST00000451244;ENST00000457962;ENST00000421199;ENST00000467833;ENST00000423015","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006366(transcription from RNA polymerase II promoter);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0007409(axonogenesis);GO:0007411(axon guidance);GO:0045893(positive regulation of transcription, DNA-templated);GO:0048813(dendrite morphogenesis);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0003713(transcription coactivator activity);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0001077(transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0008270(zinc ion binding);GO:0008270(zinc ion binding)","NA","NA","NA","Kruppel like factor 7 [Source:HGNC Symbol;Acc:HGNC:6350]",{"v":2.97169674314403,"d":"2.97"},{"v":6.26634224929821,"d":"6.27"},{"v":0.474231477458296,"d":"0.47"},{"v":-1.07633666895945,"d":"-1.08"},{"v":0.112414785948123,"d":"0.11"},{"v":0.8856800917789,"d":"0.89"},"down","no"]
["MSTRG.752","PRPF38B","ENST00000370021;ENST00000467302;ENST00000370025;ENST00000485810;ENST00000370022","GO:0003723(RNA binding);GO:0006397(mRNA processing);GO:0008380(RNA splicing);GO:0005634(nucleus);GO:0005681(spliceosomal complex);GO:0071011(precatalytic spliceosome);GO:0071011(precatalytic spliceosome)","03040(Spliceosome);03040(Spliceosome)","K12850","NA","pre-mRNA processing factor 38B [Source:HGNC Symbol;Acc:HGNC:25512]",{"v":5.78042336943442,"d":"5.78"},{"v":2.83970840450404,"d":"2.84"},{"v":2.03556934235435,"d":"2.04"},{"v":1.02543236820688,"d":"1.03"},{"v":0.112456806205775,"d":"0.11"},{"v":0.8856800917789,"d":"0.89"},"up","no"]
["ENSG00000102554","KLF5","ENST00000377687;ENST00000464404;ENST00000477333","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0005794(Golgi apparatus);GO:0043231(intracellular membrane-bounded organelle);GO:0046872(metal ion binding);GO:0005654(nucleoplasm);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0006366(transcription from RNA polymerase II promoter);GO:0001077(transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0008134(transcription factor binding);GO:0043565(sequence-specific DNA binding);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0001525(angiogenesis);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0008284(positive regulation of cell proliferation);GO:0030033(microvillus assembly);GO:0032534(regulation of microvillus assembly);GO:0035914(skeletal muscle cell differentiation);GO:0045600(positive regulation of fat cell differentiation);GO:0045893(positive regulation of transcription, DNA-templated);GO:0060576(intestinal epithelial cell development);GO:0071407(cellular response to organic cyclic compound);GO:1901653(cellular response to peptide);GO:1990830(cellular response to leukemia inhibitory factor);GO:1990830(cellular response to leukemia inhibitory factor)","NA","NA","NA","Kruppel like factor 5 [Source:HGNC Symbol;Acc:HGNC:6349]",{"v":0.511600932956589,"d":"0.51"},{"v":1.10064153917287,"d":"1.10"},{"v":0.464820665719246,"d":"0.46"},{"v":-1.1052538831417,"d":"-1.11"},{"v":0.112619574292997,"d":"0.11"},{"v":0.885981664124858,"d":"0.89"},"down","no"]
["MSTRG.11074","CHMP2B","ENST00000263780;ENST00000472024;ENST00000471660;ENST00000466696","GO:0005737(cytoplasm);GO:0006810(transport);GO:0016020(membrane);GO:0015031(protein transport);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0007034(vacuolar transport);GO:0005764(lysosome);GO:0005768(endosome);GO:0031902(late endosome membrane);GO:0045296(cadherin binding);GO:0070062(extracellular exosome);GO:0016197(endosomal transport);GO:0016236(macroautophagy);GO:0019058(viral life cycle);GO:0036258(multivesicular body assembly);GO:0039702(viral budding via host ESCRT complex);GO:0005770(late endosome);GO:0019904(protein domain specific binding);GO:0050890(cognition);GO:0005622(intracellular);GO:0007080(mitotic metaphase plate congression);GO:0010824(regulation of centrosome duplication);GO:0000920(cell separation after cytokinesis);GO:0006997(nucleus organization);GO:1901673(regulation of mitotic spindle assembly);GO:1902188(positive regulation of viral release from host cell);GO:1904903(ESCRT III complex disassembly);GO:0000815(ESCRT III complex);GO:0007032(endosome organization);GO:0070050(neuron cellular homeostasis);GO:0006914(autophagy);GO:0061763(multivesicular body-lysosome fusion);GO:0061763(multivesicular body-lysosome fusion)","04144(Endocytosis);04217(Necroptosis);04217(Necroptosis)","K12192","NA","charged multivesicular body protein 2B [Source:HGNC Symbol;Acc:HGNC:24537]",{"v":2.65776018222795,"d":"2.66"},{"v":5.62980705086928,"d":"5.63"},{"v":0.472087259512308,"d":"0.47"},{"v":-1.08287454625266,"d":"-1.08"},{"v":0.112642246119844,"d":"0.11"},{"v":0.885981664124858,"d":"0.89"},"down","no"]
["MSTRG.7215","H3F3B","ENST00000586270;ENST00000254810;ENST00000587171;ENST00000587560;ENST00000586518;ENST00000591893;ENST00000589417;ENST00000592643;ENST00000589599;ENST00000591890;ENST00000589949;ENST00000593254;ENST00000586607","GO:0005634(nucleus);GO:0003677(DNA binding);GO:0046982(protein heterodimerization activity);GO:0006334(nucleosome assembly);GO:0000786(nucleosome);GO:0005694(chromosome);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0005654(nucleoplasm);GO:0070062(extracellular exosome);GO:0044267(cellular protein metabolic process);GO:1902036(regulation of hematopoietic stem cell differentiation);GO:0043234(protein complex);GO:0000784(nuclear chromosome, telomeric region);GO:0001649(osteoblast differentiation);GO:0006997(nucleus organization);GO:0007283(spermatogenesis);GO:0007286(spermatid development);GO:0007338(single fertilization);GO:0007566(embryo implantation);GO:0008283(cell proliferation);GO:0008584(male gonad development);GO:0031508(pericentric heterochromatin assembly);GO:0031509(telomeric heterochromatin assembly);GO:0035264(multicellular organism growth);GO:0042692(muscle cell differentiation);GO:0048477(oogenesis);GO:0090230(regulation of centromere complex assembly);GO:1902340(negative regulation of chromosome condensation);GO:0001740(Barr body);GO:0045815(positive regulation of gene expression, epigenetic);GO:0042393(histone binding);GO:0030307(positive regulation of cell growth);GO:0045652(regulation of megakaryocyte differentiation);GO:0006336(DNA replication-independent nucleosome assembly);GO:0007596(blood coagulation);GO:0000228(nuclear chromosome);GO:0060964(regulation of gene silencing by miRNA);GO:0000183(chromatin silencing at rDNA);GO:0045814(negative regulation of gene expression, epigenetic);GO:0000979(RNA polymerase II core promoter sequence-specific DNA binding);GO:0031492(nucleosomal DNA binding);GO:0000980(RNA polymerase II distal enhancer sequence-specific DNA binding);GO:0000788(nuclear nucleosome);GO:0032200(telomere organization);GO:0032200(telomere organization)","05202(Transcriptional misregulation in cancers);05322(Systemic lupus erythematosus);05034(Alcoholism);05034(Alcoholism)","K11253","NA","H3 histone family member 3B [Source:HGNC Symbol;Acc:HGNC:4765]",{"v":25.3183638645256,"d":"25.32"},{"v":53.3074547773068,"d":"53.31"},{"v":0.474949778981077,"d":"0.47"},{"v":-1.07415312343414,"d":"-1.07"},{"v":0.112799914508057,"d":"0.11"},{"v":0.886317518196329,"d":"0.89"},"down","no"]
["MSTRG.4095","TNFSF13B","ENST00000375887;ENST00000486502;ENST00000479435;ENST00000430559;ENST00000493765","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0006955(immune response);GO:0048471(perinuclear region of cytoplasm);GO:0005125(cytokine activity);GO:0005615(extracellular space);GO:0005164(tumor necrosis factor receptor binding);GO:0002376(immune system process);GO:0001782(B cell homeostasis);GO:0002636(positive regulation of germinal center formation);GO:0030890(positive regulation of B cell proliferation);GO:0031295(T cell costimulation);GO:0031296(B cell costimulation);GO:0042102(positive regulation of T cell proliferation);GO:0048305(immunoglobulin secretion);GO:0050776(regulation of immune response);GO:0033209(tumor necrosis factor-mediated signaling pathway);GO:0007165(signal transduction);GO:0005102(receptor binding);GO:0008283(cell proliferation);GO:0008284(positive regulation of cell proliferation);GO:0008284(positive regulation of cell proliferation)","04064(NF-kappa B signaling pathway);04060(Cytokine-cytokine receptor interaction);04672(Intestinal immune network for IgA production);05323(Rheumatoid arthritis);05323(Rheumatoid arthritis)","K05476","NA","TNF superfamily member 13b [Source:HGNC Symbol;Acc:HGNC:11929]",{"v":7.65124159463877,"d":"7.65"},{"v":16.1317290166721,"d":"16.13"},{"v":0.474297676754378,"d":"0.47"},{"v":-1.07613529318539,"d":"-1.08"},{"v":0.1128321504231,"d":"0.11"},{"v":0.886317518196329,"d":"0.89"},"down","no"]
["ENSG00000214765","SEPT7P2","ENST00000429741;ENST00000413875;ENST00000398921;ENST00000428414;ENST00000428867;ENST00000338231;ENST00000413357","NA","NA","NA","NA","septin 7 pseudogene 2 [Source:HGNC Symbol;Acc:HGNC:32339]",{"v":0.624502726868327,"d":"0.62"},{"v":0.296624886343416,"d":"0.30"},{"v":2.10536187494839,"d":"2.11"},{"v":1.07406822869456,"d":"1.07"},{"v":0.112937767917207,"d":"0.11"},{"v":0.886568840455675,"d":"0.89"},"up","no"]
["ENSG00000258818","RNASE4","ENST00000555835;ENST00000555597","GO:0003676(nucleic acid binding);GO:0016787(hydrolase activity);GO:0090305(nucleic acid phosphodiester bond hydrolysis);GO:0005576(extracellular region);GO:0004519(endonuclease activity);GO:0090502(RNA phosphodiester bond hydrolysis, endonucleolytic);GO:0004518(nuclease activity);GO:0070062(extracellular exosome);GO:0006379(mRNA cleavage);GO:0004522(ribonuclease A activity);GO:0004540(ribonuclease activity);GO:0004540(ribonuclease activity)","NA","NA","NA","ribonuclease A family member 4 [Source:HGNC Symbol;Acc:HGNC:10047]",{"v":0.580233502870264,"d":"0.58"},{"v":1.26485869115959,"d":"1.26"},{"v":0.458733854560718,"d":"0.46"},{"v":-1.12427071263742,"d":"-1.12"},{"v":0.113276577102057,"d":"0.11"},{"v":0.887892617099914,"d":"0.89"},"down","no"]
["ENSG00000112782","CLIC5","ENST00000185206;ENST00000484572;ENST00000544153;ENST00000339561","GO:0006810(transport);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005794(Golgi apparatus);GO:0005244(voltage-gated ion channel activity);GO:0006811(ion transport);GO:0034765(regulation of ion transmembrane transport);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0005254(chloride channel activity);GO:0006821(chloride transport);GO:0034707(chloride channel complex);GO:0005815(microtubule organizing center);GO:0070062(extracellular exosome);GO:0005938(cell cortex);GO:0007605(sensory perception of sound);GO:0015629(actin cytoskeleton);GO:1902476(chloride transmembrane transport);GO:0007565(female pregnancy);GO:0060088(auditory receptor cell stereocilium organization);GO:0060088(auditory receptor cell stereocilium organization)","NA","NA","NA","chloride intracellular channel 5 [Source:HGNC Symbol;Acc:HGNC:13517]",{"v":0.232129170612426,"d":"0.23"},{"v":0.110615665555185,"d":"0.11"},{"v":2.09851985654436,"d":"2.10"},{"v":1.06937211430915,"d":"1.07"},{"v":0.113308005979761,"d":"0.11"},{"v":0.887892617099914,"d":"0.89"},"up","no"]
["ENSG00000131116","ZNF428","ENST00000300811;ENST00000595304;ENST00000598676","GO:0003676(nucleic acid binding);GO:0046872(metal ion binding);GO:0046872(metal ion binding)","NA","NA","NA","zinc finger protein 428 [Source:HGNC Symbol;Acc:HGNC:20804]",{"v":3.50578293899057,"d":"3.51"},{"v":1.7021269145868,"d":"1.70"},{"v":2.05964837812439,"d":"2.06"},{"v":1.04239806243991,"d":"1.04"},{"v":0.113327599442166,"d":"0.11"},{"v":0.887892617099914,"d":"0.89"},"up","no"]
["MSTRG.15446","TENM1","ENST00000422452","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016607(nuclear speck);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0007165(signal transduction);GO:0005794(Golgi apparatus);GO:0005783(endoplasmic reticulum);GO:0042803(protein homodimerization activity);GO:0005886(plasma membrane);GO:0005856(cytoskeleton);GO:0048471(perinuclear region of cytoplasm);GO:0007218(neuropeptide signaling pathway);GO:0005887(integral component of plasma membrane);GO:0033138(positive regulation of peptidyl-serine phosphorylation);GO:0043005(neuron projection);GO:0007399(nervous system development);GO:0006955(immune response);GO:0016363(nuclear matrix);GO:0046982(protein heterodimerization activity);GO:0005576(extracellular region);GO:0051491(positive regulation of filopodium assembly);GO:0008285(negative regulation of cell proliferation);GO:0030838(positive regulation of actin filament polymerization);GO:0050839(cell adhesion molecule binding);GO:0007157(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules);GO:0090316(positive regulation of intracellular protein transport);GO:0043406(positive regulation of MAP kinase activity);GO:0000902(cell morphogenesis);GO:0008201(heparin binding);GO:0048666(neuron development);GO:0006359(regulation of transcription from RNA polymerase III promoter)","NA","NA","NA","teneurin transmembrane protein 1 [Source:HGNC Symbol;Acc:HGNC:8117]",{"v":0.346891452078164,"d":"0.35"},{"v":0.168269733638337,"d":"0.17"},{"v":2.06152018296849,"d":"2.06"},{"v":1.04370858575958,"d":"1.04"},{"v":0.11357002292341,"d":"0.11"},{"v":0.888670779807474,"d":"0.89"},"up","no"]
["MSTRG.8125","CLC","ENST00000221804;MSTRG.8125.3;MSTRG.8125.1","GO:0005737(cytoplasm);GO:0030246(carbohydrate binding);GO:0005829(cytosol);GO:0042802(identical protein binding);GO:0005515(protein binding);GO:0002724(regulation of T cell cytokine production);GO:0007275(multicellular organism development);GO:0097153(cysteine-type endopeptidase activity involved in apoptotic process);GO:0070231(T cell apoptotic process);GO:0002667(regulation of T cell anergy);GO:0046006(regulation of activated T cell proliferation)","NA","NA","NA","Charcot-Leyden crystal galectin [Source:HGNC Symbol;Acc:HGNC:2014]",{"v":5.00668530715005,"d":"5.01"},{"v":10.6198716233635,"d":"10.62"},{"v":0.471444993377834,"d":"0.47"},{"v":-1.08483864299109,"d":"-1.08"},{"v":0.113574516701852,"d":"0.11"},{"v":0.888670779807474,"d":"0.89"},"down","no"]
["MSTRG.2610","CARNS1","ENST00000531388;ENST00000445895;ENST00000531958","GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0003824(catalytic activity);GO:0016874(ligase activity);GO:0016887(ATPase activity);GO:0005575(cellular_component);GO:0005829(cytosol);GO:0047730(carnosine synthase activity);GO:0102102(-);GO:0006548(histidine catabolic process);GO:0035499(carnosine biosynthetic process);GO:0035499(carnosine biosynthetic process)","00330(Arginine and proline metabolism);00340(Histidine metabolism);00410(beta-Alanine metabolism);00410(beta-Alanine metabolism)","K14755","EC:6.3.2.11","carnosine synthase 1 [Source:HGNC Symbol;Acc:HGNC:29268]",{"v":1.21266999065256,"d":"1.21"},{"v":0.5902983,"d":"0.59"},{"v":2.05433420806491,"d":"2.05"},{"v":1.03867090468228,"d":"1.04"},{"v":0.11367341580964,"d":"0.11"},{"v":0.888867060506285,"d":"0.89"},"up","no"]
["ENSG00000183955","KMT5A","ENST00000402868;ENST00000478781;ENST00000537270;ENST00000330479;ENST00000437519;ENST00000437502;ENST00000485469;ENST00000462311","GO:0005634(nucleus);GO:0005829(cytosol);GO:0008168(methyltransferase activity);GO:0016740(transferase activity);GO:0032259(methylation);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0016569(covalent chromatin modification);GO:0051301(cell division);GO:0005694(chromosome);GO:0005515(protein binding);GO:0007049(cell cycle);GO:0018024(histone-lysine N-methyltransferase activity);GO:0018026(peptidyl-lysine monomethylation);GO:0016279(protein-lysine N-methyltransferase activity);GO:0034968(histone lysine methylation);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0003714(transcription corepressor activity);GO:0005654(nucleoplasm);GO:0045892(negative regulation of transcription, DNA-templated);GO:1901796(regulation of signal transduction by p53 class mediator);GO:0002039(p53 binding);GO:0042799(histone methyltransferase activity (H4-K20 specific));GO:0016278(lysine N-methyltransferase activity);GO:0034770(histone H4-K20 methylation);GO:0043516(regulation of DNA damage response, signal transduction by p53 class mediator);GO:0043516(regulation of DNA damage response, signal transduction by p53 class mediator)","00310(Lysine degradation);00310(Lysine degradation)","K11428","EC:2.1.1.43","lysine methyltransferase 5A [Source:HGNC Symbol;Acc:HGNC:29489]",{"v":1.01202003450535,"d":"1.01"},{"v":2.15536954771784,"d":"2.16"},{"v":0.469534347637463,"d":"0.47"},{"v":-1.09069739631881,"d":"-1.09"},{"v":0.113754459390485,"d":"0.11"},{"v":0.88892355611955,"d":"0.89"},"down","no"]
["ENSG00000162129","CLPB","ENST00000437826;ENST00000445069;ENST00000544683;ENST00000538039;ENST00000340729;ENST00000536297","GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0016787(hydrolase activity);GO:0005739(mitochondrion);GO:0005515(protein binding);GO:0003674(molecular_function);GO:0005575(cellular_component);GO:0016887(ATPase activity);GO:0034605(cellular response to heat);GO:0034605(cellular response to heat)","04213(Longevity regulating pathway - multiple species);04213(Longevity regulating pathway - multiple species)","K03695","NA","ClpB homolog, mitochondrial AAA ATPase chaperonin [Source:HGNC Symbol;Acc:HGNC:30664]",{"v":1.64101197045028,"d":"1.64"},{"v":0.79825545239212,"d":"0.80"},{"v":2.05574790066599,"d":"2.06"},{"v":1.03966335560243,"d":"1.04"},{"v":0.113984583850739,"d":"0.11"},{"v":0.889827951759207,"d":"0.89"},"up","no"]
["MSTRG.13783","BRI3","ENST00000297290;ENST00000485422;MSTRG.13783.1;ENST00000456357;MSTRG.13783.2;ENST00000491463;ENST00000473967;ENST00000474291","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005886(plasma membrane);GO:0043312(neutrophil degranulation);GO:0035577(azurophil granule membrane);GO:0042802(identical protein binding);GO:0042802(identical protein binding)","NA","NA","NA","brain protein I3 [Source:HGNC Symbol;Acc:HGNC:1109]",{"v":1.08100140571753,"d":"1.08"},{"v":2.28643022112836,"d":"2.29"},{"v":0.472790026884815,"d":"0.47"},{"v":-1.08072849151145,"d":"-1.08"},{"v":0.114017981196185,"d":"0.11"},{"v":0.889827951759207,"d":"0.89"},"down","no"]
["MSTRG.12891","VWA7","ENST00000375688;ENST00000487013;ENST00000486423;ENST00000497645","GO:0005576(extracellular region);GO:0003674(molecular_function);GO:0008150(biological_process);GO:0005575(cellular_component);GO:0005575(cellular_component)","NA","NA","NA","von Willebrand factor A domain containing 7 [Source:HGNC Symbol;Acc:HGNC:13939]",{"v":0.229230020890599,"d":"0.23"},{"v":0.510077701759208,"d":"0.51"},{"v":0.44940215990624,"d":"0.45"},{"v":-1.15392103650543,"d":"-1.15"},{"v":0.114178080351444,"d":"0.11"},{"v":0.890500287300577,"d":"0.89"},"down","no"]
["MSTRG.210","CDA","ENST00000375071;ENST00000461985","GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0016787(hydrolase activity);GO:0003824(catalytic activity);GO:0005829(cytosol);GO:0042803(protein homodimerization activity);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0043312(neutrophil degranulation);GO:0043097(pyrimidine nucleoside salvage);GO:0030308(negative regulation of cell growth);GO:0034774(secretory granule lumen);GO:1904813(ficolin-1-rich granule lumen);GO:1904724(tertiary granule lumen);GO:0051289(protein homotetramerization);GO:0001882(nucleoside binding);GO:0007166(cell surface receptor signaling pathway);GO:0004126(cytidine deaminase activity);GO:0042802(identical protein binding);GO:0008655(pyrimidine-containing compound salvage);GO:0009972(cytidine deamination);GO:0019858(cytosine metabolic process);GO:0045980(negative regulation of nucleotide metabolic process);GO:0045980(negative regulation of nucleotide metabolic process)","00240(Pyrimidine metabolism);00983(Drug metabolism - other enzymes);00983(Drug metabolism - other enzymes)","K01489","EC:3.5.4.5","cytidine deaminase [Source:HGNC Symbol;Acc:HGNC:1712]",{"v":16.5981924018692,"d":"16.60"},{"v":34.9200211464174,"d":"34.92"},{"v":0.47532022767896,"d":"0.48"},{"v":-1.07302829675821,"d":"-1.07"},{"v":0.114442130001743,"d":"0.11"},{"v":0.891686356607439,"d":"0.89"},"down","no"]
["MSTRG.7681","UBXN6","ENST00000588238;ENST00000301281;ENST00000592358;ENST00000593024;ENST00000590466;ENST00000592515;ENST00000587009;ENST00000587324;ENST00000394765;ENST00000591919","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005765(lysosomal membrane);GO:0005829(cytosol);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0005815(microtubule organizing center);GO:0031902(late endosome membrane);GO:0003674(molecular_function);GO:0008150(biological_process);GO:0070062(extracellular exosome);GO:0043234(protein complex);GO:0031901(early endosome membrane);GO:0019898(extrinsic component of membrane);GO:0032510(endosome to lysosome transport via multivesicular body sorting pathway);GO:0016236(macroautophagy);GO:0036503(ERAD pathway);GO:0036503(ERAD pathway)","04141(Protein processing in endoplasmic reticulum);04141(Protein processing in endoplasmic reticulum)","K14011","NA","UBX domain protein 6 [Source:HGNC Symbol;Acc:HGNC:14928]",{"v":51.7596692005687,"d":"51.76"},{"v":108.575715735545,"d":"108.58"},{"v":0.476714971206254,"d":"0.48"},{"v":-1.06880116101353,"d":"-1.07"},{"v":0.114478251728542,"d":"0.11"},{"v":0.891686356607439,"d":"0.89"},"down","no"]
["MSTRG.7262","SEC14L1;SNHG20","ENST00000585618;ENST00000436233;ENST00000587491;ENST00000443798;ENST00000564509;ENST00000591786;ENST00000588880;ENST00000590483;ENST00000588696;ENST00000587821;ENST00000586390;ENST00000589202;ENST00000434411;ENST00000392476;ENST00000586429;ENST00000431431;ENST00000561633;ENST00000561721;ENST00000589827;ENST00000588721;ENST00000366365;ENST00000587820;ENST00000430767;ENST00000588616;ENST00000591413;ENST00000591437;ENST00000588488","GO:0005737(cytoplasm);GO:0016021(integral component of membrane);GO:0006810(transport);GO:0005794(Golgi apparatus);GO:0065009(regulation of molecular function);GO:0002376(immune system process);GO:0045087(innate immune response);GO:0005515(protein binding);GO:0009968(negative regulation of signal transduction);GO:0039536(negative regulation of RIG-I signaling pathway);GO:0015871(choline transport);GO:0039552(RIG-I binding);GO:0098772(molecular function regulator);GO:0098772(molecular function regulator)","NA","NA","NA","SEC14 like lipid binding 1 [Source:HGNC Symbol;Acc:HGNC:10698];small nucleolar RNA host gene 20 [Source:HGNC Symbol;Acc:HGNC:33099]",{"v":12.4351887211854,"d":"12.44"},{"v":26.0807125162735,"d":"26.08"},{"v":0.476796357209423,"d":"0.48"},{"v":-1.06855488143623,"d":"-1.07"},{"v":0.114673861815653,"d":"0.11"},{"v":0.891838534315404,"d":"0.89"},"down","no"]
["MSTRG.12833","IER3","ENST00000376377;ENST00000259874","GO:0043066(negative regulation of apoptotic process);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005515(protein binding);GO:0005829(cytosol);GO:0006915(apoptotic process);GO:0005634(nucleus);GO:0014066(regulation of phosphatidylinositol 3-kinase signaling);GO:0009653(anatomical structure morphogenesis);GO:0010941(regulation of cell death);GO:2001020(regulation of response to DNA damage stimulus);GO:2001020(regulation of response to DNA damage stimulus)","NA","NA","NA","immediate early response 3 [Source:HGNC Symbol;Acc:HGNC:5392]",{"v":6.73129026253687,"d":"6.73"},{"v":14.1839289867257,"d":"14.18"},{"v":0.474571627426821,"d":"0.47"},{"v":-1.07530224423793,"d":"-1.08"},{"v":0.114746848278526,"d":"0.11"},{"v":0.891838534315404,"d":"0.89"},"down","no"]
["MSTRG.10753","TGFBR2","ENST00000359013;ENST00000295754","GO:0010718(positive regulation of epithelial to mesenchymal transition);GO:0060412(ventricular septum morphogenesis);GO:0003151(outflow tract morphogenesis);GO:0007179(transforming growth factor beta receptor signaling pathway);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0006915(apoptotic process);GO:0004702(signal transducer, downstream of receptor, with serine/threonine kinase activity);GO:0023014(signal transduction by protein phosphorylation);GO:0030154(cell differentiation);GO:0045121(membrane raft);GO:0004872(receptor activity);GO:0007178(transmembrane receptor protein serine/threonine kinase signaling pathway);GO:0005829(cytosol);GO:0005026(transforming growth factor beta receptor activity, type II);GO:0040008(regulation of growth);GO:0043235(receptor complex);GO:0009897(external side of plasma membrane);GO:0001947(heart looping);GO:0060021(palate development);GO:0007507(heart development);GO:0001569(branching involved in blood vessel morphogenesis);GO:0034713(type I transforming growth factor beta receptor binding);GO:0030512(negative regulation of transforming growth factor beta receptor signaling pathway);GO:0060389(pathway-restricted SMAD protein phosphorylation);GO:0046332(SMAD binding);GO:0032147(activation of protein kinase activity);GO:0018105(peptidyl-serine phosphorylation);GO:0018107(peptidyl-threonine phosphorylation);GO:0003148(outflow tract septum morphogenesis);GO:0008284(positive regulation of cell proliferation);GO:0005901(caveola);GO:0002053(positive regulation of mesenchymal cell proliferation);GO:0042127(regulation of cell proliferation);GO:2000379(positive regulation of reactive oxygen species metabolic process);GO:0001570(vasculogenesis);GO:0070723(response to cholesterol);GO:0007420(brain development);GO:0050431(transforming growth factor beta binding);GO:0005539(glycosaminoglycan binding);GO:0003149(membranous septum morphogenesis);GO:0042493(response to drug);GO:0003214(cardiac left ventricle morphogenesis);GO:0002666(positive regulation of T cell tolerance induction);GO:1905007(positive regulation of epithelial to mesenchymal transition involved in endocardial cushion formation);GO:0070022(transforming growth factor beta receptor complex);GO:0048701(embryonic cranial skeleton morphogenesis);GO:0003186(tricuspid valve morphogenesis);GO:0005024(transforming growth factor beta-activated receptor activity);GO:0004675(transmembrane receptor protein serine/threonine kinase activity);GO:0001568(blood vessel development);GO:0002651(positive regulation of tolerance induction to self antigen);GO:0002663(positive regulation of B cell tolerance induction);GO:0003181(atrioventricular valve morphogenesis);GO:0003274(endocardial cushion fusion);GO:0035162(embryonic hemopoiesis);GO:0043011(myeloid dendritic cell differentiation);GO:0051138(positive regulation of NK T cell differentiation);GO:1905317(inferior endocardial cushion morphogenesis);GO:2000563(positive regulation of CD4-positive, alpha-beta T cell proliferation);GO:0031435(mitogen-activated protein kinase kinase kinase binding);GO:0001666(response to hypoxia);GO:0001701(in utero embryonic development);GO:0002088(lens development in camera-type eye);GO:0003417(growth plate cartilage development);GO:0003430(growth plate cartilage chondrocyte growth);GO:0006898(receptor-mediated endocytosis);GO:0007182(common-partner SMAD protein phosphorylation);GO:0007219(Notch signaling pathway);GO:0007224(smoothened signaling pathway);GO:0007369(gastrulation);GO:0007566(embryo implantation);GO:0007568(aging);GO:0007584(response to nutrient);GO:0008285(negative regulation of cell proliferation);GO:0009612(response to mechanical stimulus);GO:0009749(response to glucose);GO:0009887(animal organ morphogenesis);GO:0010033(response to organic substance);GO:0010468(regulation of gene expression);GO:0010634(positive regulation of epithelial cell migration);GO:0014070(response to organic cyclic compound);GO:0030324(lung development);GO:0031100(animal organ regeneration);GO:0042060(wound healing);GO:0043415(positive regulation of skeletal muscle tissue regeneration);GO:0043627(response to estrogen);GO:0045766(positive regulation of angiogenesis);GO:0048545(response to steroid hormone);GO:0048565(digestive tract development);GO:0048661(positive regulation of smooth muscle cell proliferation);GO:0051216(cartilage development);GO:0060044(negative regulation of cardiac muscle cell proliferation);GO:0060425(lung morphogenesis);GO:0060433(bronchus development);GO:0060434(bronchus morphogenesis);GO:0060439(trachea morphogenesis);GO:0060440(trachea formation);GO:0060443(mammary gland morphogenesis);GO:0060463(lung lobe morphogenesis);GO:1990086(lens fiber cell apoptotic process);GO:0005737(cytoplasm);GO:0005887(integral component of plasma membrane);GO:0009986(cell surface);GO:0009986(cell surface)","04010(MAPK signaling pathway);04350(TGF-beta signaling pathway);04390(Hippo signaling pathway);04068(FoxO signaling pathway);04060(Cytokine-cytokine receptor interaction);04144(Endocytosis);04218(Cellular senescence);04520(Adherens junction);04659(Th17 cell differentiation);04926(Relaxin signaling pathway);04380(Osteoclast differentiation);05200(Pathways in cancer);05202(Transcriptional misregulation in cancers);05210(Colorectal cancer);05212(Pancreatic cancer);05225(Hepatocellular carcinoma);05226(Gastric cancer);05220(Chronic myeloid leukemia);04933(AGE-RAGE signaling pathway in diabetic complications);05166(HTLV-I infection);05142(Chagas disease (American trypanosomiasis));05142(Chagas disease (American trypanosomiasis))","K04388","EC:2.7.11.30","transforming growth factor beta receptor 2 [Source:HGNC Symbol;Acc:HGNC:11773]",{"v":11.0327394347364,"d":"11.03"},{"v":23.1428937391582,"d":"23.14"},{"v":0.476722555056665,"d":"0.48"},{"v":-1.06877820999036,"d":"-1.07"},{"v":0.114866668427369,"d":"0.11"},{"v":0.891838534315404,"d":"0.89"},"down","no"]
["MSTRG.9315","STK17B","ENST00000263955;ENST00000420683;ENST00000449152;ENST00000606789;ENST00000409228","GO:0005634(nucleus);GO:0016020(membrane);GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0005886(plasma membrane);GO:0006915(apoptotic process);GO:0046777(protein autophosphorylation);GO:0035556(intracellular signal transduction);GO:0005793(endoplasmic reticulum-Golgi intermediate compartment);GO:2000271(positive regulation of fibroblast apoptotic process);GO:0012501(programmed cell death);GO:0015629(actin cytoskeleton);GO:0015629(actin cytoskeleton)","NA","NA","NA","serine/threonine kinase 17b [Source:HGNC Symbol;Acc:HGNC:11396]",{"v":14.0157178387538,"d":"14.02"},{"v":29.3868640548632,"d":"29.39"},{"v":0.47693819294864,"d":"0.48"},{"v":-1.06812577730225,"d":"-1.07"},{"v":0.114886149138093,"d":"0.11"},{"v":0.891838534315404,"d":"0.89"},"down","no"]
["MSTRG.14597","PEG13","ENST00000631594","NA","NA","NA","NA","paternally expressed 13 [Source:HGNC Symbol;Acc:HGNC:19969]",{"v":0.338236,"d":"0.34"},{"v":0.159406,"d":"0.16"},{"v":2.12185237694942,"d":"2.12"},{"v":1.08532428751967,"d":"1.09"},{"v":0.114912920845032,"d":"0.11"},{"v":0.891838534315404,"d":"0.89"},"up","no"]
["ENSG00000137145","DENND4C","ENST00000602925;ENST00000380427;ENST00000494124;ENST00000380437;ENST00000380424;ENST00000434457;ENST00000361024","GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0017112(Rab guanyl-nucleotide exchange factor activity);GO:0032869(cellular response to insulin stimulus);GO:0072659(protein localization to plasma membrane);GO:0032593(insulin-responsive compartment);GO:0030904(retromer complex);GO:0006810(transport);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0015031(protein transport);GO:0043547(positive regulation of GTPase activity);GO:0030659(cytoplasmic vesicle membrane);GO:0031410(cytoplasmic vesicle);GO:0005085(guanyl-nucleotide exchange factor activity);GO:0061024(membrane organization);GO:0005794(Golgi apparatus);GO:0043231(intracellular membrane-bounded organelle);GO:0043231(intracellular membrane-bounded organelle)","NA","NA","NA","DENN domain containing 4C [Source:HGNC Symbol;Acc:HGNC:26079]",{"v":3.19828612155517,"d":"3.20"},{"v":1.57845448141795,"d":"1.58"},{"v":2.02621371677573,"d":"2.03"},{"v":1.01878635176557,"d":"1.02"},{"v":0.114942152902965,"d":"0.11"},{"v":0.891838534315404,"d":"0.89"},"up","no"]
["ENSG00000151743","AMN1","ENST00000281471;ENST00000537960;ENST00000509386;ENST00000537562;ENST00000541541;ENST00000542781;ENST00000541931;ENST00000457428;ENST00000422146;ENST00000535408;ENST00000536761","NA","NA","NA","NA","antagonist of mitotic exit network 1 homolog [Source:HGNC Symbol;Acc:HGNC:27281]",{"v":0.999607184037559,"d":"1.00"},{"v":2.13397675399061,"d":"2.13"},{"v":0.4684245890534,"d":"0.47"},{"v":-1.09411128554204,"d":"-1.09"},{"v":0.115133930393448,"d":"0.12"},{"v":0.892537569542163,"d":"0.89"},"down","no"]
["ENSG00000151150","ANK3","ENST00000373827;ENST00000622427;ENST00000280772;ENST00000502769;ENST00000618080;ENST00000469721;ENST00000355288;ENST00000503366;ENST00000474360;ENST00000514197;ENST00000508449;ENST00000616444;ENST00000513049;ENST00000459732;ENST00000612776","GO:0010628(positive regulation of gene expression);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0007165(signal transduction);GO:0005794(Golgi apparatus);GO:0005886(plasma membrane);GO:0005856(cytoskeleton);GO:0042995(cell projection);GO:0005515(protein binding);GO:0030054(cell junction);GO:0045202(synapse);GO:0045211(postsynaptic membrane);GO:0005764(lysosome);GO:0030424(axon);GO:0005829(cytosol);GO:0045296(cadherin binding);GO:0042383(sarcolemma);GO:0016323(basolateral plasma membrane);GO:0009986(cell surface);GO:0005783(endoplasmic reticulum);GO:0044325(ion channel binding);GO:0006888(ER to Golgi vesicle-mediated transport);GO:0016328(lateral plasma membrane);GO:0007528(neuromuscular junction development);GO:0034112(positive regulation of homotypic cell-cell adhesion);GO:0016529(sarcoplasmic reticulum);GO:0030018(Z disc);GO:0030674(protein binding, bridging);GO:0033268(node of Ranvier);GO:0043194(axon initial segment);GO:0045184(establishment of protein localization);GO:0030315(T-tubule);GO:0030425(dendrite);GO:0014704(intercalated disc);GO:0007016(cytoskeletal anchoring at plasma membrane);GO:0014731(spectrin-associated cytoskeleton);GO:0019228(neuronal action potential);GO:0031594(neuromuscular junction);GO:0008092(cytoskeletal protein binding);GO:0072659(protein localization to plasma membrane);GO:0043005(neuron projection);GO:0071286(cellular response to magnesium ion);GO:0005200(structural constituent of cytoskeleton);GO:0030507(spectrin binding);GO:2000651(positive regulation of sodium ion transmembrane transporter activity);GO:0007409(axonogenesis);GO:0043266(regulation of potassium ion transport);GO:1902260(negative regulation of delayed rectifier potassium channel activity);GO:0072661(protein targeting to plasma membrane);GO:0005923(bicellular tight junction);GO:0045838(positive regulation of membrane potential);GO:0010765(positive regulation of sodium ion transport);GO:0007009(plasma membrane organization);GO:0000281(mitotic cytokinesis);GO:0043001(Golgi to plasma membrane protein transport);GO:0071709(membrane assembly);GO:2001259(positive regulation of cation channel activity);GO:0043034(costamere);GO:0010960(magnesium ion homeostasis);GO:0009925(basal plasma membrane);GO:0010650(positive regulation of cell communication by electrical coupling);GO:0072660(maintenance of protein location in plasma membrane);GO:0090314(positive regulation of protein targeting to membrane);GO:1900827(positive regulation of membrane depolarization during cardiac muscle cell action potential);GO:1900827(positive regulation of membrane depolarization during cardiac muscle cell action potential)","05205(Proteoglycans in cancer);05205(Proteoglycans in cancer)","K10380","NA","ankyrin 3 [Source:HGNC Symbol;Acc:HGNC:494]",{"v":0.332584763722964,"d":"0.33"},{"v":0.161937533224018,"d":"0.16"},{"v":2.05378430251176,"d":"2.05"},{"v":1.03828467141409,"d":"1.04"},{"v":0.115218497961243,"d":"0.12"},{"v":0.892537569542163,"d":"0.89"},"up","no"]
["ENSG00000164821","DEFA4","ENST00000297435","GO:0005615(extracellular space);GO:0005576(extracellular region);GO:0042803(protein homodimerization activity);GO:0045087(innate immune response);GO:0006952(defense response);GO:0042742(defense response to bacterium);GO:0050829(defense response to Gram-negative bacterium);GO:0019731(antibacterial humoral response);GO:0050830(defense response to Gram-positive bacterium);GO:0061844(antimicrobial humoral immune response mediated by antimicrobial peptide);GO:0043312(neutrophil degranulation);GO:0042582(azurophil granule);GO:0019730(antimicrobial humoral response);GO:0035580(specific granule lumen);GO:0005796(Golgi lumen);GO:0031640(killing of cells of other organism);GO:0019732(antifungal humoral response);GO:0050832(defense response to fungus)","NA","NA","NA","defensin alpha 4 [Source:HGNC Symbol;Acc:HGNC:2763]",{"v":1.490965,"d":"1.49"},{"v":3.258002,"d":"3.26"},{"v":0.457631701883547,"d":"0.46"},{"v":-1.12774109835239,"d":"-1.13"},{"v":0.11525460227853,"d":"0.12"},{"v":0.892537569542163,"d":"0.89"},"down","no"]
["ENSG00000104177","MYEF2","ENST00000324324;ENST00000561301;ENST00000560530;ENST00000560157;ENST00000560513;ENST00000561351;ENST00000561151;ENST00000616409;ENST00000267836;ENST00000558289","GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0000981(RNA polymerase II transcription factor activity, sequence-specific DNA binding);GO:0003697(single-stranded DNA binding);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0005634(nucleus);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0030182(neuron differentiation);GO:0014902(myotube differentiation);GO:0014902(myotube differentiation)","NA","NA","NA","myelin expression factor 2 [Source:HGNC Symbol;Acc:HGNC:17940]",{"v":0.141813672069382,"d":"0.14"},{"v":0.0681175249875595,"d":"0.07"},{"v":2.08189701688783,"d":"2.08"},{"v":1.05789870605336,"d":"1.06"},{"v":0.115580689341129,"d":"0.12"},{"v":0.894487571366241,"d":"0.89"},"up","no"]
["ENSG00000111196","MAGOHB","ENST00000546173;ENST00000543929;ENST00000625272;ENST00000398874;ENST00000545236;ENST00000320756;ENST00000544850;ENST00000537852;ENST00000544176","GO:0005634(nucleus);GO:0043025(neuronal cell body);GO:0003723(RNA binding);GO:0006397(mRNA processing);GO:0006810(transport);GO:0008380(RNA splicing);GO:0051028(mRNA transport);GO:0005515(protein binding);GO:0005654(nucleoplasm);GO:0006369(termination of RNA polymerase II transcription);GO:0006405(RNA export from nucleus);GO:0031124(mRNA 3'-end processing);GO:0000398(mRNA splicing, via spliceosome);GO:0000184(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay);GO:0006406(mRNA export from nucleus);GO:0071013(catalytic step 2 spliceosome);GO:0035145(exon-exon junction complex);GO:0035145(exon-exon junction complex)","03040(Spliceosome);03013(RNA transport);03015(mRNA surveillance pathway);03015(mRNA surveillance pathway)","K12877","NA","mago homolog B, exon junction complex core component [Source:HGNC Symbol;Acc:HGNC:25504]",{"v":0.503646607907743,"d":"0.50"},{"v":0.242105539950577,"d":"0.24"},{"v":2.08027708911806,"d":"2.08"},{"v":1.05677570551637,"d":"1.06"},{"v":0.115710498878942,"d":"0.12"},{"v":0.894917037572395,"d":"0.89"},"up","no"]
["ENSG00000148343","MIGA2","ENST00000439290;ENST00000477088;ENST00000450073;ENST00000474534;ENST00000474639;ENST00000414342;ENST00000483458;ENST00000494608;ENST00000471943;ENST00000445183;ENST00000492279;ENST00000495975;ENST00000358369","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005739(mitochondrion);GO:0042803(protein homodimerization activity);GO:0005741(mitochondrial outer membrane);GO:0008053(mitochondrial fusion);GO:0005887(integral component of plasma membrane);GO:0005515(protein binding);GO:0046982(protein heterodimerization activity);GO:0060348(bone development);GO:0060348(bone development)","NA","NA","NA","mitoguardin 2 [Source:HGNC Symbol;Acc:HGNC:23621]",{"v":2.28766706759759,"d":"2.29"},{"v":1.12218710171374,"d":"1.12"},{"v":2.03857900710496,"d":"2.04"},{"v":1.02756387095436,"d":"1.03"},{"v":0.115837150247517,"d":"0.12"},{"v":0.895321542542105,"d":"0.90"},"up","no"]
["ENSG00000133624","ZNF767P","ENST00000463567;ENST00000472212;ENST00000493198;ENST00000481762;ENST00000486492;ENST00000513792","NA","NA","NA","NA","zinc finger family member 767, pseudogene [Source:HGNC Symbol;Acc:HGNC:21884]",{"v":1.41418632352941,"d":"1.41"},{"v":2.9918686388335,"d":"2.99"},{"v":0.472676609251397,"d":"0.47"},{"v":-1.08107462124636,"d":"-1.08"},{"v":0.115948986949514,"d":"0.12"},{"v":0.895611097399644,"d":"0.90"},"down","no"]
["MSTRG.149","PGD","ENST00000270776;ENST00000465632;ENST00000460189;ENST00000493288;ENST00000491493;ENST00000487775;ENST00000483936;ENST00000477958;ENST00000498356;ENST00000496718","GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0004616(phosphogluconate dehydrogenase (decarboxylating) activity);GO:0006098(pentose-phosphate shunt);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0009051(pentose-phosphate shunt, oxidative branch);GO:0019322(pentose biosynthetic process);GO:0019521(D-gluconate metabolic process);GO:0019521(D-gluconate metabolic process)","00030(Pentose phosphate pathway);00480(Glutathione metabolism);00480(Glutathione metabolism)","K00033","EC:1.1.1.44;EC:1.1.1.343","phosphogluconate dehydrogenase [Source:HGNC Symbol;Acc:HGNC:8891]",{"v":49.6953849285233,"d":"49.70"},{"v":103.920230160486,"d":"103.92"},{"v":0.478207032949963,"d":"0.48"},{"v":-1.06429274708913,"d":"-1.06"},{"v":0.11605711636968,"d":"0.12"},{"v":0.895776042269814,"d":"0.90"},"down","no"]
["MSTRG.1185","SELL","MSTRG.1185.1;ENST00000236147;ENST00000460650;ENST00000497295;ENST00000479657;ENST00000463108;ENST00000466340","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0030246(carbohydrate binding);GO:0007155(cell adhesion);GO:0050839(cell adhesion molecule binding);GO:0033198(response to ATP);GO:0050900(leukocyte migration);GO:0005886(plasma membrane);GO:0009897(external side of plasma membrane);GO:0009986(cell surface);GO:0050776(regulation of immune response);GO:0005515(protein binding);GO:0005887(integral component of plasma membrane);GO:0043312(neutrophil degranulation);GO:0030667(secretory granule membrane);GO:0008201(heparin binding);GO:0002020(protease binding);GO:0043208(glycosphingolipid binding);GO:0043208(glycosphingolipid binding)","04514(Cell adhesion molecules (CAMs));04514(Cell adhesion molecules (CAMs))","K06495","NA","selectin L [Source:HGNC Symbol;Acc:HGNC:10720]",{"v":143.52834055971,"d":"143.53"},{"v":300.040712075862,"d":"300.04"},{"v":0.478362884712193,"d":"0.48"},{"v":-1.06382263703796,"d":"-1.06"},{"v":0.116119116590532,"d":"0.12"},{"v":0.895776042269814,"d":"0.90"},"down","no"]
["MSTRG.2090","TALDO1","ENST00000528070;ENST00000319006;ENST00000528097;ENST00000530440;ENST00000530666;ENST00000530119;ENST00000533796;ENST00000532202;ENST00000532685","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016740(transferase activity);GO:0003824(catalytic activity);GO:0005975(carbohydrate metabolic process);GO:0005515(protein binding);GO:0006098(pentose-phosphate shunt);GO:0004801(sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glyceronetransferase activity);GO:0030246(carbohydrate binding);GO:0048029(monosaccharide binding);GO:0006002(fructose 6-phosphate metabolic process);GO:0009052(pentose-phosphate shunt, non-oxidative branch);GO:0019682(glyceraldehyde-3-phosphate metabolic process);GO:0005829(cytosol);GO:0043231(intracellular membrane-bounded organelle);GO:0070062(extracellular exosome);GO:0035722(interleukin-12-mediated signaling pathway);GO:0005999(xylulose biosynthetic process);GO:0005999(xylulose biosynthetic process)","00030(Pentose phosphate pathway);00030(Pentose phosphate pathway)","K00616","EC:2.2.1.2","transaldolase 1 [Source:HGNC Symbol;Acc:HGNC:11559]",{"v":46.3532762552413,"d":"46.35"},{"v":96.8800037168053,"d":"96.88"},{"v":0.478460719208257,"d":"0.48"},{"v":-1.06352760806456,"d":"-1.06"},{"v":0.116399951531139,"d":"0.12"},{"v":0.896929035071111,"d":"0.90"},"down","no"]
["MSTRG.4338","PNN","ENST00000216832;ENST00000553331;ENST00000554117;ENST00000554902","GO:0003723(RNA binding);GO:0006397(mRNA processing);GO:0008380(RNA splicing);GO:0005634(nucleus);GO:0016607(nuclear speck);GO:0016020(membrane);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0005681(spliceosomal complex);GO:0030054(cell junction);GO:0005886(plasma membrane);GO:0000398(mRNA splicing, via spliceosome);GO:0007155(cell adhesion);GO:0035145(exon-exon junction complex);GO:0005198(structural molecule activity);GO:0005911(cell-cell junction);GO:0071013(catalytic step 2 spliceosome);GO:0030057(desmosome);GO:0005882(intermediate filament);GO:0005882(intermediate filament)","03013(RNA transport);03015(mRNA surveillance pathway);03015(mRNA surveillance pathway)","K13114","NA","pinin, desmosome associated protein [Source:HGNC Symbol;Acc:HGNC:9162]",{"v":3.23637110378481,"d":"3.24"},{"v":6.78206736253273,"d":"6.78"},{"v":0.477195364007149,"d":"0.48"},{"v":-1.06734806768906,"d":"-1.07"},{"v":0.116585011188752,"d":"0.12"},{"v":0.896929035071111,"d":"0.90"},"down","no"]
["MSTRG.3775","AC026366.1","ENST00000488803;MSTRG.3775.2","NA","NA","NA","NA",null,{"v":202.253874770193,"d":"202.25"},{"v":100.415253,"d":"100.42"},{"v":2.01417482631043,"d":"2.01"},{"v":1.01018891179784,"d":"1.01"},{"v":0.116586755243542,"d":"0.12"},{"v":0.896929035071111,"d":"0.90"},"up","no"]
["ENSG00000109756","RAPGEF2","ENST00000264431;ENST00000505478;ENST00000510253;ENST00000502485;ENST00000514565;ENST00000511336;ENST00000510510;ENST00000513816;ENST00000503328;ENST00000504604;ENST00000512056;ENST00000505026;ENST00000509891","GO:0005096(GTPase activator activity);GO:0043547(positive regulation of GTPase activity);GO:0042127(regulation of cell proliferation);GO:0017034(Rap guanyl-nucleotide exchange factor activity);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0007264(small GTPase mediated signal transduction);GO:0007165(signal transduction);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0004871(signal transducer activity);GO:0007186(G-protein coupled receptor signaling pathway);GO:0030552(cAMP binding);GO:0007275(multicellular organism development);GO:0048471(perinuclear region of cytoplasm);GO:0030054(cell junction);GO:0045202(synapse);GO:0007399(nervous system development);GO:0030154(cell differentiation);GO:0007218(neuropeptide signaling pathway);GO:0005509(calcium ion binding);GO:0005085(guanyl-nucleotide exchange factor activity);GO:0005887(integral component of plasma membrane);GO:0005923(bicellular tight junction);GO:0005768(endosome);GO:2001224(positive regulation of neuron migration);GO:0008285(negative regulation of cell proliferation);GO:0000165(MAPK cascade);GO:0043234(protein complex);GO:0005770(late endosome);GO:0043005(neuron projection);GO:0016324(apical plasma membrane);GO:0070374(positive regulation of ERK1 and ERK2 cascade);GO:2000670(positive regulation of dendritic cell apoptotic process);GO:0032092(positive regulation of protein binding);GO:0019933(cAMP-mediated signaling);GO:0061028(establishment of endothelial barrier);GO:0071321(cellular response to cGMP);GO:0005088(Ras guanyl-nucleotide exchange factor activity);GO:0005911(cell-cell junction);GO:0035556(intracellular signal transduction);GO:0048167(regulation of synaptic plasticity);GO:0030165(PDZ domain binding);GO:0043950(positive regulation of cAMP-mediated signaling);GO:0031175(neuron projection development);GO:0030033(microvillus assembly);GO:0045860(positive regulation of protein kinase activity);GO:0030139(endocytic vesicle);GO:0071320(cellular response to cAMP);GO:0001568(blood vessel development);GO:0010976(positive regulation of neuron projection development);GO:0001764(neuron migration);GO:0043025(neuronal cell body);GO:0070300(phosphatidic acid binding);GO:0071880(adenylate cyclase-activating adrenergic receptor signaling pathway);GO:0072659(protein localization to plasma membrane);GO:0019992(diacylglycerol binding);GO:0032486(Rap protein signal transduction);GO:0038180(nerve growth factor signaling pathway);GO:1990090(cellular response to nerve growth factor stimulus);GO:2001214(positive regulation of vasculogenesis);GO:0090557(establishment of endothelial intestinal barrier);GO:1901888(regulation of cell junction assembly);GO:0050699(WW domain binding);GO:0050774(negative regulation of dendrite morphogenesis);GO:2000481(positive regulation of cAMP-dependent protein kinase activity);GO:0031547(brain-derived neurotrophic factor receptor signaling pathway);GO:0031697(beta-1 adrenergic receptor binding);GO:0021591(ventricular system development);GO:0021884(forebrain neuron development);GO:0048022(negative regulation of melanin biosynthetic process);GO:0005622(intracellular);GO:0005622(intracellular)","04015(Rap1 signaling pathway);04010(MAPK signaling pathway);04530(Tight junction);04530(Tight junction)","K08018","NA","Rap guanine nucleotide exchange factor 2 [Source:HGNC Symbol;Acc:HGNC:16854]",{"v":1.30282805947522,"d":"1.30"},{"v":2.72881450395668,"d":"2.73"},{"v":0.477433719875854,"d":"0.48"},{"v":-1.06662763114947,"d":"-1.07"},{"v":0.11665915715707,"d":"0.12"},{"v":0.896929035071111,"d":"0.90"},"down","no"]
["MSTRG.9713","ROMO1","ENST00000374077;ENST00000374072;ENST00000374078;ENST00000336695","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005743(mitochondrial inner membrane);GO:0005739(mitochondrion);GO:0042742(defense response to bacterium);GO:0003674(molecular_function);GO:0050829(defense response to Gram-negative bacterium);GO:2000379(positive regulation of reactive oxygen species metabolic process);GO:0050830(defense response to Gram-positive bacterium);GO:0061844(antimicrobial humoral immune response mediated by antimicrobial peptide);GO:0008284(positive regulation of cell proliferation);GO:0031640(killing of cells of other organism);GO:0051715(cytolysis in other organism);GO:0034614(cellular response to reactive oxygen species);GO:0001302(replicative cell aging);GO:0001302(replicative cell aging)","NA","NA","NA","reactive oxygen species modulator 1 [Source:HGNC Symbol;Acc:HGNC:16185]",{"v":6.58575339031339,"d":"6.59"},{"v":3.17532646438746,"d":"3.18"},{"v":2.07403977643723,"d":"2.07"},{"v":1.05244356277142,"d":"1.05"},{"v":0.116711998529288,"d":"0.12"},{"v":0.896929035071111,"d":"0.90"},"up","no"]
["MSTRG.2864","PAFAH1B2","ENST00000527958;ENST00000419197;ENST00000533677;ENST00000533206","GO:0005737(cytoplasm);GO:0005730(nucleolus);GO:0005829(cytosol);GO:0016787(hydrolase activity);GO:0001650(fibrillar center);GO:0006629(lipid metabolic process);GO:0016042(lipid catabolic process);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0070062(extracellular exosome);GO:0043312(neutrophil degranulation);GO:0034774(secretory granule lumen);GO:1904813(ficolin-1-rich granule lumen);GO:0016239(positive regulation of macroautophagy);GO:0007420(brain development);GO:0004623(phospholipase A2 activity);GO:0003847(1-alkyl-2-acetylglycerophosphocholine esterase activity);GO:0042803(protein homodimerization activity);GO:0046982(protein heterodimerization activity);GO:0047179(platelet-activating factor acetyltransferase activity);GO:0007283(spermatogenesis);GO:0007283(spermatogenesis)","00565(Ether lipid metabolism);00565(Ether lipid metabolism)","K16795","EC:3.1.1.47","platelet activating factor acetylhydrolase 1b catalytic subunit 2 [Source:HGNC Symbol;Acc:HGNC:8575]",{"v":3.04649693032095,"d":"3.05"},{"v":6.37241412626689,"d":"6.37"},{"v":0.478075791992769,"d":"0.48"},{"v":-1.06468874014549,"d":"-1.06"},{"v":0.116807678353419,"d":"0.12"},{"v":0.896929035071111,"d":"0.90"},"down","no"]
["ENSG00000138336","TET1","ENST00000373644","GO:0005634(nucleus);GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0016569(covalent chromatin modification);GO:0003677(DNA binding);GO:0051213(dioxygenase activity);GO:0005506(iron ion binding);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0008284(positive regulation of cell proliferation);GO:0006493(protein O-linked glycosylation);GO:0070579(methylcytosine dioxygenase activity);GO:0080111(DNA demethylation);GO:0019827(stem cell population maintenance);GO:0090310(negative regulation of methylation-dependent chromatin silencing);GO:0001826(inner cell mass cell differentiation);GO:0031062(positive regulation of histone methylation)","NA","NA","NA","tet methylcytosine dioxygenase 1 [Source:HGNC Symbol;Acc:HGNC:29484]",{"v":0.189917,"d":"0.19"},{"v":0.090334,"d":"0.09"},{"v":2.10238669825315,"d":"2.10"},{"v":1.07202805290714,"d":"1.07"},{"v":0.117016414511979,"d":"0.12"},{"v":0.896929035071111,"d":"0.90"},"up","no"]
["MSTRG.14468","TP53INP1","ENST00000448464;ENST00000342697","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0010506(regulation of autophagy);GO:0006915(apoptotic process);GO:0006914(autophagy);GO:0031410(cytoplasmic vesicle);GO:0098869(cellular oxidant detoxification);GO:0008285(negative regulation of cell proliferation);GO:0045893(positive regulation of transcription, DNA-templated);GO:0005515(protein binding);GO:0005654(nucleoplasm);GO:0010508(positive regulation of autophagy);GO:0000045(autophagosome assembly);GO:0007050(cell cycle arrest);GO:0005776(autophagosome);GO:0042981(regulation of apoptotic process);GO:1901796(regulation of signal transduction by p53 class mediator);GO:0016605(PML body);GO:0030336(negative regulation of cell migration);GO:0006950(response to stress);GO:0016209(antioxidant activity);GO:0048102(autophagic cell death);GO:0009408(response to heat);GO:0010628(positive regulation of gene expression);GO:0010629(negative regulation of gene expression);GO:0034644(cellular response to UV);GO:0043065(positive regulation of apoptotic process);GO:0048147(negative regulation of fibroblast proliferation);GO:0071361(cellular response to ethanol);GO:0071447(cellular response to hydroperoxide);GO:0072703(cellular response to methyl methanesulfonate);GO:1904761(negative regulation of myofibroblast differentiation);GO:2001235(positive regulation of apoptotic signaling pathway);GO:2001235(positive regulation of apoptotic signaling pathway)","05166(HTLV-I infection);05166(HTLV-I infection)","K15310","NA","tumor protein p53 inducible nuclear protein 1 [Source:HGNC Symbol;Acc:HGNC:18022]",{"v":6.23671643498943,"d":"6.24"},{"v":13.0296480673009,"d":"13.03"},{"v":0.47865578584897,"d":"0.48"},{"v":-1.06293954657443,"d":"-1.06"},{"v":0.117056867612522,"d":"0.12"},{"v":0.896929035071111,"d":"0.90"},"down","no"]
["MSTRG.3504","MARCH9","ENST00000266643;ENST00000548358;ENST00000552279","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0016740(transferase activity);GO:0016567(protein ubiquitination);GO:0005794(Golgi apparatus);GO:0005765(lysosomal membrane);GO:0000139(Golgi membrane);GO:0005764(lysosome);GO:0005802(trans-Golgi network);GO:0005795(Golgi stack);GO:0005795(Golgi stack)","NA","NA","NA","membrane associated ring-CH-type finger 9 [Source:HGNC Symbol;Acc:HGNC:25139]",{"v":1.38016740224719,"d":"1.38"},{"v":2.90369386117353,"d":"2.90"},{"v":0.475314364472773,"d":"0.48"},{"v":-1.07304609290946,"d":"-1.07"},{"v":0.117123046770224,"d":"0.12"},{"v":0.896929035071111,"d":"0.90"},"down","no"]
["ENSG00000151240","DIP2C","ENST00000280886;ENST00000421992;ENST00000634311","GO:0003824(catalytic activity);GO:0008152(metabolic process);GO:0003674(molecular_function);GO:0008150(biological_process);GO:0005575(cellular_component);GO:0005575(cellular_component)","NA","NA","NA","disco interacting protein 2 homolog C [Source:HGNC Symbol;Acc:HGNC:29150]",{"v":0.267298780217214,"d":"0.27"},{"v":0.129720430690179,"d":"0.13"},{"v":2.06057579977994,"d":"2.06"},{"v":1.04304753518125,"d":"1.04"},{"v":0.117262281251006,"d":"0.12"},{"v":0.896929035071111,"d":"0.90"},"up","no"]
["ENSG00000084731","KIF3C","ENST00000455394;ENST00000496378;ENST00000475453;ENST00000264712","GO:0005737(cytoplasm);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0003777(microtubule motor activity);GO:0005856(cytoskeleton);GO:0008017(microtubule binding);GO:0005874(microtubule);GO:0003774(motor activity);GO:0007018(microtubule-based movement);GO:0035735(intraciliary transport involved in cilium assembly);GO:0005929(cilium);GO:0097542(ciliary tip);GO:0005829(cytosol);GO:0006890(retrograde vesicle-mediated transport, Golgi to ER);GO:0072384(organelle transport along microtubule);GO:0016887(ATPase activity);GO:0019886(antigen processing and presentation of exogenous peptide antigen via MHC class II);GO:0005871(kinesin complex);GO:0005871(kinesin complex)","NA","NA","NA","kinesin family member 3C [Source:HGNC Symbol;Acc:HGNC:6321]",{"v":1.08384560268624,"d":"1.08"},{"v":2.27511735342808,"d":"2.28"},{"v":0.47639107541118,"d":"0.48"},{"v":-1.06978170851286,"d":"-1.07"},{"v":0.117410566317686,"d":"0.12"},{"v":0.896929035071111,"d":"0.90"},"down","no"]
["MSTRG.674","CTBS","ENST00000370625;ENST00000370630;ENST00000477677;ENST00000465118","GO:0016787(hydrolase activity);GO:0005975(carbohydrate metabolic process);GO:0008152(metabolic process);GO:0004553(hydrolase activity, hydrolyzing O-glycosyl compounds);GO:0016798(hydrolase activity, acting on glycosyl bonds);GO:0005615(extracellular space);GO:0008061(chitin binding);GO:0005764(lysosome);GO:0070062(extracellular exosome);GO:0004568(chitinase activity);GO:0006032(chitin catabolic process);GO:0009313(oligosaccharide catabolic process);GO:0009313(oligosaccharide catabolic process)","NA","NA","NA","chitobiase [Source:HGNC Symbol;Acc:HGNC:2496]",{"v":1.95298073007638,"d":"1.95"},{"v":4.08082083398184,"d":"4.08"},{"v":0.47857546545869,"d":"0.48"},{"v":-1.06318165699206,"d":"-1.06"},{"v":0.117435720448771,"d":"0.12"},{"v":0.896929035071111,"d":"0.90"},"down","no"]
["ENSG00000166788","SAAL1","ENST00000300013;ENST00000531751;ENST00000531216;ENST00000532403;ENST00000533851;ENST00000534721;ENST00000528002;ENST00000524803;ENST00000530180;ENST00000530237","GO:0005581(collagen trimer);GO:0005615(extracellular space);GO:0005615(extracellular space)","NA","NA","NA","serum amyloid A like 1 [Source:HGNC Symbol;Acc:HGNC:25158]",{"v":0.531226597394137,"d":"0.53"},{"v":1.12622089771987,"d":"1.13"},{"v":0.471689522428194,"d":"0.47"},{"v":-1.08409054004226,"d":"-1.08"},{"v":0.117559779718372,"d":"0.12"},{"v":0.896929035071111,"d":"0.90"},"down","no"]
["MSTRG.14503","YWHAZ","MSTRG.14503.1;ENST00000395956;ENST00000353245;ENST00000457309;ENST00000395958;ENST00000395957;ENST00000395953;MSTRG.14503.3;ENST00000419477;MSTRG.14503.6;ENST00000395951;ENST00000395948;ENST00000522819;ENST00000521328;ENST00000480304;MSTRG.14503.4;MSTRG.14503.13;ENST00000521309;ENST00000492736;ENST00000517727;ENST00000418997;ENST00000523131;ENST00000523848;ENST00000518736;ENST00000522542;ENST00000521607;ENST00000437293","GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0004497(monooxygenase activity);GO:0055114(oxidation-reduction process);GO:0019904(protein domain specific binding);GO:0005515(protein binding);GO:0042470(melanosome);GO:0005615(extracellular space);GO:0005925(focal adhesion);GO:0042802(identical protein binding);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0045296(cadherin binding);GO:0070062(extracellular exosome);GO:0019901(protein kinase binding);GO:0061024(membrane organization);GO:0072562(blood microparticle);GO:0043488(regulation of mRNA stability);GO:0006605(protein targeting);GO:0010941(regulation of cell death);GO:0005739(mitochondrion);GO:0007165(signal transduction);GO:0008134(transcription factor binding);GO:0030168(platelet activation);GO:0043066(negative regulation of apoptotic process);GO:0031982(vesicle);GO:0051683(establishment of Golgi localization);GO:0090168(Golgi reassembly);GO:1900740(positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway);GO:0031625(ubiquitin protein ligase binding);GO:0030659(cytoplasmic vesicle membrane);GO:0044325(ion channel binding);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0016310(phosphorylation)","04390(Hippo signaling pathway);04151(PI3K-Akt signaling pathway);04110(Cell cycle);04114(Oocyte meiosis);05203(Viral carcinogenesis);05130(Pathogenic Escherichia coli infection);05161(Hepatitis B);05169(Epstein-Barr virus infection);05169(Epstein-Barr virus infection)","K16197","NA","tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta [Source:HGNC Symbol;Acc:HGNC:12855]",{"v":19.7952008123784,"d":"19.80"},{"v":41.2918234862144,"d":"41.29"},{"v":0.479397593545056,"d":"0.48"},{"v":-1.06070542784718,"d":"-1.06"},{"v":0.117560890397966,"d":"0.12"},{"v":0.896929035071111,"d":"0.90"},"down","no"]
["MSTRG.7146","LRRC37A16P","MSTRG.7146.1","NA","NA","NA","NA",null,{"v":5.777846,"d":"5.78"},{"v":2.823518,"d":"2.82"},{"v":2.04632872891195,"d":"2.05"},{"v":1.03303792293077,"d":"1.03"},{"v":0.117572335383881,"d":"0.12"},{"v":0.896929035071111,"d":"0.90"},"up","no"]
["MSTRG.3990","LCP1","ENST00000469227;ENST00000323076;ENST00000494531;ENST00000460190;MSTRG.3990.3;MSTRG.3990.2;MSTRG.3990.1;ENST00000416500","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0046872(metal ion binding);GO:0005829(cytosol);GO:0005509(calcium ion binding);GO:0003779(actin binding);GO:0005886(plasma membrane);GO:0015629(actin cytoskeleton);GO:0005856(cytoskeleton);GO:0042995(cell projection);GO:0005615(extracellular space);GO:0030054(cell junction);GO:0005925(focal adhesion);GO:0042802(identical protein binding);GO:0051015(actin filament binding);GO:0031100(animal organ regeneration);GO:0051017(actin filament bundle assembly);GO:0001726(ruffle);GO:0001891(phagocytic cup);GO:0005884(actin filament);GO:0030175(filopodium);GO:0070062(extracellular exosome);GO:0022617(extracellular matrix disassembly);GO:0002102(podosome);GO:0001725(stress fiber);GO:0032587(ruffle membrane);GO:0035722(interleukin-12-mediated signaling pathway);GO:0016477(cell migration);GO:0051639(actin filament network formation);GO:0051020(GTPase binding);GO:0032432(actin filament bundle);GO:0002286(T cell activation involved in immune response);GO:0010737(protein kinase A signaling);GO:0033157(regulation of intracellular protein transport);GO:0051764(actin crosslink formation);GO:0071803(positive regulation of podosome assembly);GO:0071803(positive regulation of podosome assembly)","NA","NA","NA","lymphocyte cytosolic protein 1 [Source:HGNC Symbol;Acc:HGNC:6528]",{"v":91.1115281952674,"d":"91.11"},{"v":189.896060762409,"d":"189.90"},{"v":0.479796831116275,"d":"0.48"},{"v":-1.05950446570106,"d":"-1.06"},{"v":0.11761245645836,"d":"0.12"},{"v":0.896929035071111,"d":"0.90"},"down","no"]
["MSTRG.3998","ITM2B","ENST00000378565;ENST00000463839;ENST00000607866;ENST00000378549","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005794(Golgi apparatus);GO:0043231(intracellular membrane-bounded organelle);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0000139(Golgi membrane);GO:0005615(extracellular space);GO:0005768(endosome);GO:0070062(extracellular exosome);GO:0044267(cellular protein metabolic process);GO:0031301(integral component of organelle membrane);GO:0010008(endosome membrane);GO:0030660(Golgi-associated vesicle membrane);GO:0007399(nervous system development);GO:0001540(amyloid-beta binding);GO:0005524(ATP binding);GO:0042985(negative regulation of amyloid precursor protein biosynthetic process);GO:0042985(negative regulation of amyloid precursor protein biosynthetic process)","NA","NA","NA","integral membrane protein 2B [Source:HGNC Symbol;Acc:HGNC:6174]",{"v":30.4106498785504,"d":"30.41"},{"v":63.3546443472086,"d":"63.35"},{"v":0.480006638690732,"d":"0.48"},{"v":-1.05887373584531,"d":"-1.06"},{"v":0.117826136487456,"d":"0.12"},{"v":0.896929035071111,"d":"0.90"},"down","no"]
["MSTRG.5036","B2M","ENST00000544417;ENST00000349264;MSTRG.5036.1;ENST00000559720;ENST00000560681;ENST00000559916;ENST00000559907;ENST00000623550;ENST00000558401;ENST00000632133;ENST00000561139;ENST00000557901;ENST00000559220;ENST00000561424;ENST00000560556","GO:0016020(membrane);GO:0005794(Golgi apparatus);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0006955(immune response);GO:0005615(extracellular space);GO:0002376(immune system process);GO:0005925(focal adhesion);GO:0050776(regulation of immune response);GO:0042802(identical protein binding);GO:0002474(antigen processing and presentation of peptide antigen via MHC class I);GO:0042612(MHC class I protein complex);GO:0070062(extracellular exosome);GO:0044267(cellular protein metabolic process);GO:0001895(retina homeostasis);GO:0002479(antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent);GO:0045087(innate immune response);GO:0043312(neutrophil degranulation);GO:0030670(phagocytic vesicle membrane);GO:0009986(cell surface);GO:1990712(HFE-transferrin receptor complex);GO:0005788(endoplasmic reticulum lumen);GO:0035580(specific granule lumen);GO:1904724(tertiary granule lumen);GO:0000139(Golgi membrane);GO:0048260(positive regulation of receptor-mediated endocytosis);GO:0060333(interferon-gamma-mediated signaling pathway);GO:0012507(ER to Golgi transport vesicle membrane);GO:0032092(positive regulation of protein binding);GO:0050690(regulation of defense response to virus by virus);GO:0031901(early endosome membrane);GO:0002480(antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent);GO:0055038(recycling endosome membrane);GO:0002726(positive regulation of T cell cytokine production);GO:0019885(antigen processing and presentation of endogenous peptide antigen via MHC class I);GO:0055072(iron ion homeostasis);GO:0071281(cellular response to iron ion);GO:0001916(positive regulation of T cell mediated cytotoxicity);GO:0002237(response to molecule of bacterial origin);GO:0002481(antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent);GO:0006826(iron ion transport);GO:0010977(negative regulation of neuron projection development);GO:0033077(T cell differentiation in thymus);GO:0033216(ferric iron import);GO:0042026(protein refolding);GO:0042493(response to drug);GO:0045646(regulation of erythrocyte differentiation);GO:0046686(response to cadmium ion);GO:0071283(cellular response to iron(III) ion);GO:1900121(negative regulation of receptor binding);GO:1900122(positive regulation of receptor binding);GO:1904434(positive regulation of ferrous iron binding);GO:1904437(positive regulation of transferrin receptor binding);GO:1904440(positive regulation of ferrous iron import across plasma membrane);GO:0009897(external side of plasma membrane);GO:0031905(early endosome lumen);GO:0031905(early endosome lumen)","04612(Antigen processing and presentation);04612(Antigen processing and presentation)","K08055","NA","beta-2-microglobulin [Source:HGNC Symbol;Acc:HGNC:914]",{"v":132.835660884039,"d":"132.84"},{"v":276.699360724756,"d":"276.70"},{"v":0.480072164012609,"d":"0.48"},{"v":-1.05867680814145,"d":"-1.06"},{"v":0.117884302512509,"d":"0.12"},{"v":0.896929035071111,"d":"0.90"},"down","no"]
["ENSG00000151239","TWF1","ENST00000395510;ENST00000551789;ENST00000546662;ENST00000546506;ENST00000552521;ENST00000548315;ENST00000547961;ENST00000547564;ENST00000547459;ENST00000550371","GO:0048471(perinuclear region of cytoplasm);GO:0030837(negative regulation of actin filament polymerization);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0003779(actin binding);GO:0005622(intracellular);GO:0005856(cytoskeleton);GO:0005925(focal adhesion);GO:0045296(cadherin binding);GO:0015629(actin cytoskeleton);GO:0005911(cell-cell junction);GO:0005524(ATP binding);GO:0003785(actin monomer binding);GO:0032587(ruffle membrane);GO:0030175(filopodium);GO:0030016(myofibril);GO:0005546(phosphatidylinositol-4,5-bisphosphate binding);GO:0042989(sequestering of actin monomers);GO:0043538(regulation of actin phosphorylation);GO:0032403(protein complex binding);GO:0010613(positive regulation of cardiac muscle hypertrophy);GO:0051016(barbed-end actin filament capping);GO:0051016(barbed-end actin filament capping)","NA","NA","NA","twinfilin actin binding protein 1 [Source:HGNC Symbol;Acc:HGNC:9620]",{"v":2.44041182171923,"d":"2.44"},{"v":5.12047564750763,"d":"5.12"},{"v":0.476598657960045,"d":"0.48"},{"v":-1.06915320579542,"d":"-1.07"},{"v":0.117888656521002,"d":"0.12"},{"v":0.896929035071111,"d":"0.90"},"down","no"]
["MSTRG.14589","SLA","ENST00000520106;ENST00000427060;ENST00000523224;ENST00000395352;ENST00000518594;ENST00000519504;ENST00000518565;ENST00000517648;ENST00000522002;ENST00000521302;ENST00000522432;ENST00000338087;ENST00000519558;ENST00000522119;ENST00000521823;ENST00000519341;ENST00000517549;ENST00000517615","GO:0005737(cytoplasm);GO:0009967(positive regulation of signal transduction);GO:0005515(protein binding);GO:0009966(regulation of signal transduction);GO:0045087(innate immune response);GO:0005070(SH3/SH2 adaptor activity);GO:0005768(endosome);GO:0030154(cell differentiation);GO:0042127(regulation of cell proliferation);GO:0016477(cell migration);GO:0005102(receptor binding);GO:0038083(peptidyl-tyrosine autophosphorylation);GO:0031234(extrinsic component of cytoplasmic side of plasma membrane);GO:0004715(non-membrane spanning protein tyrosine kinase activity);GO:0007169(transmembrane receptor protein tyrosine kinase signaling pathway);GO:0007169(transmembrane receptor protein tyrosine kinase signaling pathway)","NA","NA","NA","Src like adaptor [Source:HGNC Symbol;Acc:HGNC:10902]",{"v":10.2297869938457,"d":"10.23"},{"v":21.3208802847977,"d":"21.32"},{"v":0.479801342965177,"d":"0.48"},{"v":-1.05949089914328,"d":"-1.06"},{"v":0.117909383720094,"d":"0.12"},{"v":0.896929035071111,"d":"0.90"},"down","no"]
["MSTRG.8849","POLE4","ENST00000483063;ENST00000485527;ENST00000465242;ENST00000459636;ENST00000233699;ENST00000473023","GO:0005634(nucleus);GO:0016740(transferase activity);GO:0003677(DNA binding);GO:0046982(protein heterodimerization activity);GO:0005515(protein binding);GO:0016779(nucleotidyltransferase activity);GO:0003887(DNA-directed DNA polymerase activity);GO:0071897(DNA biosynthetic process);GO:0005654(nucleoplasm);GO:0000082(G1/S transition of mitotic cell cycle);GO:0043966(histone H3 acetylation);GO:0005671(Ada2/Gcn5/Ada3 transcription activator complex);GO:0006270(DNA replication initiation);GO:0032201(telomere maintenance via semi-conservative replication);GO:0008622(epsilon DNA polymerase complex);GO:0008622(epsilon DNA polymerase complex)","00230(Purine metabolism);00240(Pyrimidine metabolism);03030(DNA replication);03410(Base excision repair);03420(Nucleotide excision repair);05166(HTLV-I infection);05166(HTLV-I infection)","K03506","EC:2.7.7.7","DNA polymerase epsilon 4, accessory subunit [Source:HGNC Symbol;Acc:HGNC:18755]",{"v":1.52084247326825,"d":"1.52"},{"v":3.20140459646676,"d":"3.20"},{"v":0.475054754074737,"d":"0.48"},{"v":-1.0738342890657,"d":"-1.07"},{"v":0.117940291421896,"d":"0.12"},{"v":0.896929035071111,"d":"0.90"},"down","no"]
["MSTRG.7987","JUND","ENST00000252818","GO:0005634(nucleus);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0005515(protein binding);GO:0032870(cellular response to hormone stimulus);GO:0000790(nuclear chromatin);GO:0008134(transcription factor binding);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0000981(RNA polymerase II transcription factor activity, sequence-specific DNA binding);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:0019899(enzyme binding);GO:0032496(response to lipopolysaccharide);GO:0042127(regulation of cell proliferation);GO:0044212(transcription regulatory region DNA binding);GO:0034097(response to cytokine);GO:0042493(response to drug);GO:0051726(regulation of cell cycle);GO:0000785(chromatin);GO:0003713(transcription coactivator activity);GO:0009314(response to radiation);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0035976(transcription factor AP-1 complex);GO:0009612(response to mechanical stimulus);GO:0045597(positive regulation of cell differentiation);GO:0051591(response to cAMP);GO:0010941(regulation of cell death);GO:0001077(transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0003690(double-stranded DNA binding);GO:0016922(ligand-dependent nuclear receptor binding);GO:0043565(sequence-specific DNA binding);GO:0002076(osteoblast development);GO:0006366(transcription from RNA polymerase II promoter);GO:0007568(aging);GO:0007623(circadian rhythm);GO:0009416(response to light stimulus);GO:0014070(response to organic cyclic compound);GO:0043434(response to peptide hormone);GO:0045669(positive regulation of osteoblast differentiation);GO:0071277(cellular response to calcium ion);GO:0032993(protein-DNA complex);GO:0043234(protein complex)","04010(MAPK signaling pathway);04657(IL-17 signaling pathway);04380(Osteoclast differentiation)","K04449","NA","JunD proto-oncogene, AP-1 transcription factor subunit [Source:HGNC Symbol;Acc:HGNC:6206]",{"v":14.515835,"d":"14.52"},{"v":30.279902,"d":"30.28"},{"v":0.47938844055704,"d":"0.48"},{"v":-1.06073297303443,"d":"-1.06"},{"v":0.117954164992909,"d":"0.12"},{"v":0.896929035071111,"d":"0.90"},"down","no"]
["MSTRG.1255","FAM129A","ENST00000367511;ENST00000461167;ENST00000487074;ENST00000496299;ENST00000417056","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0001933(negative regulation of protein phosphorylation);GO:0001934(positive regulation of protein phosphorylation);GO:0034976(response to endoplasmic reticulum stress);GO:0045727(positive regulation of translation);GO:0003674(molecular_function);GO:0070062(extracellular exosome);GO:0006417(regulation of translation);GO:0006417(regulation of translation)","NA","NA","NA","family with sequence similarity 129 member A [Source:HGNC Symbol;Acc:HGNC:16784]",{"v":21.7229594806498,"d":"21.72"},{"v":45.2375930817009,"d":"45.24"},{"v":0.480197066219179,"d":"0.48"},{"v":-1.05830150548807,"d":"-1.06"},{"v":0.118069645267517,"d":"0.12"},{"v":0.896929035071111,"d":"0.90"},"down","no"]
["MSTRG.2541","DPF2","ENST00000524666;ENST00000252268;ENST00000528416;ENST00000444314;ENST00000530973;ENST00000415073;ENST00000532052;ENST00000531989;ENST00000532102;ENST00000532492","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0043231(intracellular membrane-bounded organelle);GO:0046872(metal ion binding);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0000790(nuclear chromatin);GO:0005813(centrosome);GO:0005515(protein binding);GO:0006915(apoptotic process);GO:0097190(apoptotic signaling pathway);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding)","NA","NA","NA","double PHD fingers 2 [Source:HGNC Symbol;Acc:HGNC:9964]",{"v":4.11246443421905,"d":"4.11"},{"v":8.57905612832145,"d":"8.58"},{"v":0.4793609428248,"d":"0.48"},{"v":-1.0608157284294,"d":"-1.06"},{"v":0.118077241447248,"d":"0.12"},{"v":0.896929035071111,"d":"0.90"},"down","no"]
["ENSG00000188549","C15orf52","ENST00000382688;ENST00000559313;ENST00000558912","GO:0003723(RNA binding);GO:0003723(RNA binding)","NA","NA","NA","chromosome 15 open reading frame 52 [Source:HGNC Symbol;Acc:HGNC:33488]",{"v":0.22755617150466,"d":"0.23"},{"v":0.486717288015979,"d":"0.49"},{"v":0.46753254323933,"d":"0.47"},{"v":-1.09686130563907,"d":"-1.10"},{"v":0.118176238701628,"d":"0.12"},{"v":0.896929035071111,"d":"0.90"},"down","no"]
["MSTRG.7736","SLC25A23","ENST00000301454;ENST00000334510;ENST00000598908;ENST00000595267;ENST00000600682;ENST00000598704;ENST00000597039;ENST00000264088","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0055085(transmembrane transport);GO:0046872(metal ion binding);GO:0005739(mitochondrion);GO:0005743(mitochondrial inner membrane);GO:0005509(calcium ion binding);GO:0005515(protein binding);GO:0006839(mitochondrial transport);GO:0015866(ADP transport);GO:0006851(mitochondrial calcium ion transmembrane transport);GO:0015867(ATP transport);GO:0005347(ATP transmembrane transporter activity);GO:0015217(ADP transmembrane transporter activity);GO:0036444(mitochondrial calcium uptake);GO:0002082(regulation of oxidative phosphorylation);GO:0043457(regulation of cellular respiration);GO:0051282(regulation of sequestering of calcium ion);GO:0051503(adenine nucleotide transport);GO:0071277(cellular response to calcium ion);GO:0097274(urea homeostasis);GO:0097274(urea homeostasis)","NA","NA","NA","solute carrier family 25 member 23 [Source:HGNC Symbol;Acc:HGNC:19375]",{"v":4.81209880798518,"d":"4.81"},{"v":2.38372953550113,"d":"2.38"},{"v":2.01872684644717,"d":"2.02"},{"v":1.01344571307844,"d":"1.01"},{"v":0.11820606350402,"d":"0.12"},{"v":0.896929035071111,"d":"0.90"},"up","no"]
["MSTRG.3946","N4BP2L2","MSTRG.3946.1","NA","NA","NA","NA",null,{"v":6.760355,"d":"6.76"},{"v":3.26706,"d":"3.27"},{"v":2.06924727430779,"d":"2.07"},{"v":1.04910605704012,"d":"1.05"},{"v":0.118279630268471,"d":"0.12"},{"v":0.896929035071111,"d":"0.90"},"up","no"]
["MSTRG.4567","ERG28","ENST00000256319","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0006629(lipid metabolic process);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0006694(steroid biosynthetic process);GO:0008202(steroid metabolic process);GO:0016126(sterol biosynthetic process);GO:0003674(molecular_function);GO:0008150(biological_process);GO:0030133(transport vesicle);GO:0030674(protein binding, bridging);GO:0006696(ergosterol biosynthetic process)","NA","NA","NA","ergosterol biosynthesis 28 homolog [Source:HGNC Symbol;Acc:HGNC:1187]",{"v":2.466113,"d":"2.47"},{"v":1.213691,"d":"1.21"},{"v":2.03191174689439,"d":"2.03"},{"v":1.02283774212839,"d":"1.02"},{"v":0.118364915638328,"d":"0.12"},{"v":0.897010896234578,"d":"0.90"},"up","no"]
["MSTRG.4470","ZBTB25","ENST00000608382;ENST00000555424;ENST00000555220;ENST00000394715","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0005654(nucleoplasm);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0010467(gene expression);GO:0010467(gene expression)","NA","NA","NA","zinc finger and BTB domain containing 25 [Source:HGNC Symbol;Acc:HGNC:13112]",{"v":1.16941344263636,"d":"1.17"},{"v":0.579849783220214,"d":"0.58"},{"v":2.01675240118568,"d":"2.02"},{"v":1.01203397363449,"d":"1.01"},{"v":0.118690767363402,"d":"0.12"},{"v":0.897938040809636,"d":"0.90"},"up","no"]
["ENSG00000084764","MAPRE3","ENST00000233121;ENST00000491354;ENST00000494788;ENST00000475633;ENST00000405074;ENST00000458529","GO:0005737(cytoplasm);GO:0051301(cell division);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0007049(cell cycle);GO:0008017(microtubule binding);GO:0005874(microtubule);GO:0042802(identical protein binding);GO:0045893(positive regulation of transcription, DNA-templated);GO:0045737(positive regulation of cyclin-dependent protein serine/threonine kinase activity);GO:0030496(midbody);GO:1903033(positive regulation of microtubule plus-end binding);GO:0015630(microtubule cytoskeleton);GO:0035371(microtubule plus-end);GO:0035371(microtubule plus-end)","NA","NA","NA","microtubule associated protein RP/EB family member 3 [Source:HGNC Symbol;Acc:HGNC:6892]",{"v":0.348648460248627,"d":"0.35"},{"v":0.775035844752819,"d":"0.78"},{"v":0.449848174905795,"d":"0.45"},{"v":-1.15248992515439,"d":"-1.15"},{"v":0.11877516893006,"d":"0.12"},{"v":0.897938040809636,"d":"0.90"},"down","no"]
["MSTRG.4380","VCPKMT;SOS2","ENST00000484763;MSTRG.4380.4;ENST00000555794;ENST00000216373;ENST00000556452;ENST00000491402;ENST00000395860;ENST00000543680;ENST00000569518;ENST00000395859","GO:0005737(cytoplasm);GO:0008168(methyltransferase activity);GO:0016740(transferase activity);GO:0032259(methylation);GO:0018023(peptidyl-lysine trimethylation);GO:0016279(protein-lysine N-methyltransferase activity);GO:0018022(peptidyl-lysine methylation);GO:0005515(protein binding);GO:0005575(cellular_component);GO:0005829(cytosol);GO:0043234(protein complex);GO:0006479(protein methylation);GO:0051117(ATPase binding);GO:0032780(negative regulation of ATPase activity);GO:0007264(small GTPase mediated signal transduction);GO:0003677(DNA binding);GO:0046982(protein heterodimerization activity);GO:0005089(Rho guanyl-nucleotide exchange factor activity);GO:0035023(regulation of Rho protein signal transduction);GO:0043547(positive regulation of GTPase activity);GO:0005085(guanyl-nucleotide exchange factor activity);GO:0051056(regulation of small GTPase mediated signal transduction);GO:0043065(positive regulation of apoptotic process);GO:0051057(positive regulation of small GTPase mediated signal transduction);GO:0032780(negative regulation of ATPase activity)","04014(Ras signaling pathway);04010(MAPK signaling pathway);04012(ErbB signaling pathway);04630(Jak-STAT signaling pathway);04068(FoxO signaling pathway);04072(Phospholipase D signaling pathway);04151(PI3K-Akt signaling pathway);04150(mTOR signaling pathway);04510(Focal adhesion);04540(Gap junction);04810(Regulation of actin cytoskeleton);04650(Natural killer cell mediated cytotoxicity);04660(T cell receptor signaling pathway);04662(B cell receptor signaling pathway);04664(Fc epsilon RI signaling pathway);04062(Chemokine signaling pathway);04910(Insulin signaling pathway);04912(GnRH signaling pathway);04915(Estrogen signaling pathway);04917(Prolactin signaling pathway);04926(Relaxin signaling pathway);04722(Neurotrophin signaling pathway);05200(Pathways in cancer);05231(Choline metabolism in cancer);05206(MicroRNAs in cancer);05205(Proteoglycans in cancer);05225(Hepatocellular carcinoma);05226(Gastric cancer);05214(Glioma);05221(Acute myeloid leukemia);05220(Chronic myeloid leukemia);05211(Renal cell carcinoma);05215(Prostate cancer);05213(Endometrial cancer);05224(Breast cancer);05223(Non-small cell lung cancer);05034(Alcoholism);05160(Hepatitis C);05165(Human papillomavirus infection);01521(EGFR tyrosine kinase inhibitor resistance);01522(Endocrine resistance);01522(Endocrine resistance)","K03099","NA","valosin containing protein lysine methyltransferase [Source:HGNC Symbol;Acc:HGNC:20352];SOS Ras/Rho guanine nucleotide exchange factor 2 [Source:HGNC Symbol;Acc:HGNC:11188]",{"v":2.17997469959473,"d":"2.18"},{"v":4.54129087183384,"d":"4.54"},{"v":0.480034149126067,"d":"0.48"},{"v":-1.05879105359025,"d":"-1.06"},{"v":0.118781621719599,"d":"0.12"},{"v":0.897938040809636,"d":"0.90"},"down","no"]
["ENSG00000180190","TDRP","ENST00000324079","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0043231(intracellular membrane-bounded organelle);GO:0005829(cytosol);GO:0007283(spermatogenesis);GO:0003674(molecular_function)","NA","NA","NA","testis development related protein [Source:HGNC Symbol;Acc:HGNC:26951]",{"v":0.269150300304456,"d":"0.27"},{"v":0.584282976750623,"d":"0.58"},{"v":0.460650594000331,"d":"0.46"},{"v":-1.11825522152293,"d":"-1.12"},{"v":0.118846315963127,"d":"0.12"},{"v":0.897938040809636,"d":"0.90"},"down","no"]
["ENSG00000037042","TUBG2","ENST00000251412;ENST00000590396;ENST00000588870","GO:0005737(cytoplasm);GO:0005525(GTP binding);GO:0000166(nucleotide binding);GO:0003924(GTPase activity);GO:0005856(cytoskeleton);GO:0005874(microtubule);GO:0005815(microtubule organizing center);GO:0007017(microtubule-based process);GO:0007020(microtubule nucleation);GO:0031122(cytoplasmic microtubule organization);GO:0005829(cytosol);GO:0000930(gamma-tubulin complex);GO:0005198(structural molecule activity);GO:0015630(microtubule cytoskeleton);GO:0000242(pericentriolar material);GO:0005813(centrosome);GO:0005876(spindle microtubule);GO:0005881(cytoplasmic microtubule);GO:0005881(cytoplasmic microtubule)","05165(Human papillomavirus infection);05165(Human papillomavirus infection)","K10389","NA","tubulin gamma 2 [Source:HGNC Symbol;Acc:HGNC:12419]",{"v":1.38324309920635,"d":"1.38"},{"v":0.674219708152958,"d":"0.67"},{"v":2.05162068459224,"d":"2.05"},{"v":1.03676402185983,"d":"1.04"},{"v":0.118862980634808,"d":"0.12"},{"v":0.897938040809636,"d":"0.90"},"up","no"]
["MSTRG.14042","AC093673.1","ENST00000429630","NA","NA","NA","NA",null,{"v":1.509127,"d":"1.51"},{"v":3.299045,"d":"3.30"},{"v":0.457443593524793,"d":"0.46"},{"v":-1.12833423642858,"d":"-1.13"},{"v":0.118965173110712,"d":"0.12"},{"v":0.897938040809636,"d":"0.90"},"down","no"]
["ENSG00000054654","SYNE2","ENST00000358025;ENST00000554805;ENST00000557307;ENST00000555002;ENST00000554928;ENST00000556342;ENST00000557005;ENST00000555323;ENST00000441438;ENST00000639659;ENST00000357395;ENST00000553289;ENST00000554997;ENST00000556725;ENST00000553455;ENST00000344113;ENST00000553308;ENST00000555612;ENST00000557084;ENST00000458046;ENST00000394768;ENST00000557060;ENST00000557024","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0031965(nuclear membrane);GO:0051015(actin filament binding);GO:0003779(actin binding);GO:0005739(mitochondrion);GO:0045111(intermediate filament cytoskeleton);GO:0005886(plasma membrane);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0016235(aggresome);GO:0034993(LINC complex);GO:0030054(cell junction);GO:0005654(nucleoplasm);GO:0005925(focal adhesion);GO:0090286(cytoskeletal anchoring at nuclear membrane);GO:0005635(nuclear envelope);GO:0070062(extracellular exosome);GO:0016529(sarcoplasmic reticulum);GO:0030335(positive regulation of cell migration);GO:0033017(sarcoplasmic reticulum membrane);GO:0030018(Z disc);GO:0031527(filopodium membrane);GO:0031258(lamellipodium membrane);GO:0051642(centrosome localization);GO:0005640(nuclear outer membrane);GO:0031981(nuclear lumen);GO:0007097(nuclear migration);GO:0031022(nuclear migration along microfilament);GO:0006998(nuclear envelope organization);GO:0007163(establishment or maintenance of cell polarity);GO:0010761(fibroblast migration);GO:0021817(nucleokinesis involved in cell motility in cerebral cortex radial glia guided migration);GO:0034504(protein localization to nucleus);GO:1902017(regulation of cilium assembly);GO:0030016(myofibril);GO:0030016(myofibril)","NA","NA","NA","spectrin repeat containing nuclear envelope protein 2 [Source:HGNC Symbol;Acc:HGNC:17084]",{"v":3.32249451679735,"d":"3.32"},{"v":1.65627559431376,"d":"1.66"},{"v":2.00600342612302,"d":"2.01"},{"v":1.00432406998124,"d":"1.00"},{"v":0.119041627858476,"d":"0.12"},{"v":0.897938040809636,"d":"0.90"},"up","no"]
["ENSG00000135749","PCNX2","ENST00000344698;ENST00000258229;ENST00000475463;ENST00000520463;ENST00000519530;ENST00000484041;ENST00000497623;ENST00000498302;ENST00000484347;ENST00000522067;ENST00000496675;ENST00000490102;ENST00000429988;ENST00000488780;ENST00000430153;ENST00000517808;ENST00000462233","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0003674(molecular_function);GO:0008150(biological_process);GO:0005575(cellular_component);GO:0005575(cellular_component)","NA","NA","NA","pecanex homolog 2 [Source:HGNC Symbol;Acc:HGNC:8736]",{"v":0.808511271516468,"d":"0.81"},{"v":0.39733275548317,"d":"0.40"},{"v":2.03484676347232,"d":"2.03"},{"v":1.02492015473601,"d":"1.02"},{"v":0.119083794317637,"d":"0.12"},{"v":0.897938040809636,"d":"0.90"},"up","no"]
["ENSG00000186448","ZNF197","ENST00000344387;ENST00000334075;ENST00000396058;ENST00000383745;ENST00000383744","GO:0005634(nucleus);GO:0006355(regulation of transcription, DNA-templated);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0003676(nucleic acid binding);GO:0046872(metal ion binding);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0005622(intracellular);GO:0005622(intracellular)","NA","NA","NA","zinc finger protein 197 [Source:HGNC Symbol;Acc:HGNC:12988]",{"v":0.685595758829614,"d":"0.69"},{"v":0.334826945913994,"d":"0.33"},{"v":2.04761225820135,"d":"2.05"},{"v":1.03394254828182,"d":"1.03"},{"v":0.11933602882157,"d":"0.12"},{"v":0.898040865407249,"d":"0.90"},"up","no"]
["MSTRG.1881","ENTPD1-AS1","ENST00000449419;ENST00000451364;ENST00000414006;ENST00000452942;ENST00000427846;ENST00000427300;ENST00000454638;ENST00000444375;ENST00000416301;ENST00000458228","NA","NA","NA","NA","ENTPD1 antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:45203]",{"v":0.127074257104087,"d":"0.13"},{"v":0.276107143997446,"d":"0.28"},{"v":0.460235310337578,"d":"0.46"},{"v":-1.11955642011573,"d":"-1.12"},{"v":0.119377207831853,"d":"0.12"},{"v":0.898040865407249,"d":"0.90"},"down","no"]
["MSTRG.11870","AC139713.2;GUSBP5","ENST00000514475;ENST00000641741;ENST00000642059;ENST00000510536;ENST00000641328;ENST00000641428;ENST00000510805;ENST00000641556;ENST00000506982;ENST00000499587;ENST00000509873","NA","NA","NA","NA","glucuronidase, beta pseudogene 5 [Source:HGNC Symbol;Acc:HGNC:42319]",{"v":0.0512215765251516,"d":"0.05"},{"v":0.11246631730289,"d":"0.11"},{"v":0.455439261758733,"d":"0.46"},{"v":-1.13466942857078,"d":"-1.13"},{"v":0.119385484089624,"d":"0.12"},{"v":0.898040865407249,"d":"0.90"},"down","no"]
["MSTRG.8158","C19orf54","ENST00000378313;ENST00000596809;ENST00000470681;ENST00000469741;ENST00000596940;ENST00000600139","NA","NA","NA","NA","chromosome 19 open reading frame 54 [Source:HGNC Symbol;Acc:HGNC:24758]",{"v":0.65764362962963,"d":"0.66"},{"v":0.311228645925926,"d":"0.31"},{"v":2.11305623128969,"d":"2.11"},{"v":1.07933115985371,"d":"1.08"},{"v":0.119521906777994,"d":"0.12"},{"v":0.898040865407249,"d":"0.90"},"up","no"]
["MSTRG.8766","AFTPH","ENST00000238856;ENST00000422803;ENST00000409933;ENST00000487769;ENST00000238855;ENST00000409183;ENST00000498706","GO:0006810(transport);GO:0005737(cytoplasm);GO:0015031(protein transport);GO:0005794(Golgi apparatus);GO:0043231(intracellular membrane-bounded organelle);GO:0005634(nucleus);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0030276(clathrin binding);GO:0030121(AP-1 adaptor complex);GO:0030121(AP-1 adaptor complex)","NA","NA","NA","aftiphilin [Source:HGNC Symbol;Acc:HGNC:25951]",{"v":3.66199428732443,"d":"3.66"},{"v":7.62234335685798,"d":"7.62"},{"v":0.480428933187542,"d":"0.48"},{"v":-1.05760505685539,"d":"-1.06"},{"v":0.119534032484588,"d":"0.12"},{"v":0.898040865407249,"d":"0.90"},"down","no"]
["ENSG00000261526","AC012615.1","ENST00000565797","NA","NA","NA","NA",null,{"v":2.691451,"d":"2.69"},{"v":1.315915,"d":"1.32"},{"v":2.04530763765137,"d":"2.05"},{"v":1.03231785731568,"d":"1.03"},{"v":0.119580325108732,"d":"0.12"},{"v":0.898040865407249,"d":"0.90"},"up","no"]
["MSTRG.12015","TTC33","ENST00000337702;ENST00000636106;ENST00000503936;ENST00000636863","GO:0005515(protein binding);GO:0005515(protein binding)","NA","NA","NA","tetratricopeptide repeat domain 33 [Source:HGNC Symbol;Acc:HGNC:29959]",{"v":0.431276774666471,"d":"0.43"},{"v":0.903480639055857,"d":"0.90"},{"v":0.477350322766361,"d":"0.48"},{"v":-1.06687966007166,"d":"-1.07"},{"v":0.119619460896299,"d":"0.12"},{"v":0.898040865407249,"d":"0.90"},"down","no"]
["MSTRG.11800","ALPK1","ENST00000505912;ENST00000509688;ENST00000458497;ENST00000504488;ENST00000514594;ENST00000505176;ENST00000177648;ENST00000505127;ENST00000508589;ENST00000502366;ENST00000515106;ENST00000509722;ENST00000512847;ENST00000426472;ENST00000504745;ENST00000504176;ENST00000509209","GO:0004674(protein serine/threonine kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0005737(cytoplasm);GO:0005737(cytoplasm)","NA","NA","NA","alpha kinase 1 [Source:HGNC Symbol;Acc:HGNC:20917]",{"v":2.17726787318458,"d":"2.18"},{"v":4.53267236900609,"d":"4.53"},{"v":0.480349713355083,"d":"0.48"},{"v":-1.05784296817888,"d":"-1.06"},{"v":0.119725453686392,"d":"0.12"},{"v":0.89827658149005,"d":"0.90"},"down","no"]
["MSTRG.7380","SMCHD1","MSTRG.7380.2;ENST00000320876;ENST00000584897;ENST00000577880;ENST00000581383;ENST00000583800;ENST00000585229;ENST00000581631;ENST00000581711;ENST00000583344;ENST00000581226;ENST00000577300;ENST00000583441","GO:0005524(ATP binding);GO:0005694(chromosome);GO:0051276(chromosome organization);GO:0000784(nuclear chromosome, telomeric region);GO:0016887(ATPase activity);GO:0009048(dosage compensation by inactivation of X chromosome);GO:0043584(nose development);GO:0060821(inactivation of X chromosome by DNA methylation);GO:0001740(Barr body);GO:0001740(Barr body)","NA","NA","NA","structural maintenance of chromosomes flexible hinge domain containing 1 [Source:HGNC Symbol;Acc:HGNC:29090]",{"v":15.3249710655201,"d":"15.32"},{"v":31.8022226410319,"d":"31.80"},{"v":0.481883648149406,"d":"0.48"},{"v":-1.05324324822741,"d":"-1.05"},{"v":0.119894025103425,"d":"0.12"},{"v":0.898981226834028,"d":"0.90"},"down","no"]
["MSTRG.2208","DNHD1;TIMM10B;AC084337.2","ENST00000254579;ENST00000254616;ENST00000640959;ENST00000533635;ENST00000354685;ENST00000533379;ENST00000525883;ENST00000532467;ENST00000531462;ENST00000528908;ENST00000530751;ENST00000533649;ENST00000473019;ENST00000529821;ENST00000472080;ENST00000532027;ENST00000534210","GO:0003777(microtubule motor activity);GO:0007018(microtubule-based movement);GO:0030286(dynein complex);GO:0070062(extracellular exosome);GO:0051959(dynein light intermediate chain binding);GO:0045503(dynein light chain binding);GO:0045505(dynein intermediate chain binding);GO:0008569(ATP-dependent microtubule motor activity, minus-end-directed);GO:0003341(cilium movement);GO:0036159(inner dynein arm assembly);GO:0036156(inner dynein arm);GO:0006810(transport);GO:0016020(membrane);GO:0015031(protein transport);GO:0046872(metal ion binding);GO:0005743(mitochondrial inner membrane);GO:0005739(mitochondrion);GO:0005515(protein binding);GO:0005758(mitochondrial intermembrane space);GO:0007160(cell-matrix adhesion);GO:0006626(protein targeting to mitochondrion);GO:0042719(mitochondrial intermembrane space protein transporter complex);GO:0036156(inner dynein arm)","NA","NA","NA","dynein heavy chain domain 1 [Source:HGNC Symbol;Acc:HGNC:26532];translocase of inner mitochondrial membrane 10B [Source:HGNC Symbol;Acc:HGNC:4022]",{"v":0.488092977900309,"d":"0.49"},{"v":0.241198572562858,"d":"0.24"},{"v":2.02361470349543,"d":"2.02"},{"v":1.01693462685462,"d":"1.02"},{"v":0.120089889751777,"d":"0.12"},{"v":0.899889516111323,"d":"0.90"},"up","no"]
["MSTRG.14051","EPHA1-AS1","MSTRG.14051.1","NA","NA","NA","NA",null,{"v":9.075892,"d":"9.08"},{"v":4.381827,"d":"4.38"},{"v":2.07125749145277,"d":"2.07"},{"v":1.05050691548521,"d":"1.05"},{"v":0.12030019480492,"d":"0.12"},{"v":0.900904817065202,"d":"0.90"},"up","no"]
["MSTRG.7156","KCNJ2","ENST00000243457;ENST00000535240","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005244(voltage-gated ion channel activity);GO:0006811(ion transport);GO:0006813(potassium ion transport);GO:0034765(regulation of ion transmembrane transport);GO:0005242(inward rectifier potassium channel activity);GO:0005886(plasma membrane);GO:0005887(integral component of plasma membrane);GO:0061337(cardiac conduction);GO:0051289(protein homotetramerization);GO:0060306(regulation of membrane repolarization);GO:0090076(relaxation of skeletal muscle);GO:0031224(intrinsic component of membrane);GO:0008076(voltage-gated potassium channel complex);GO:0086002(cardiac muscle cell action potential involved in contraction);GO:0086091(regulation of heart rate by cardiac conduction);GO:0010107(potassium ion import);GO:0086012(membrane depolarization during cardiac muscle cell action potential);GO:0030007(cellular potassium ion homeostasis);GO:0055119(relaxation of cardiac muscle);GO:0086013(membrane repolarization during cardiac muscle cell action potential);GO:0086008(voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization);GO:0071805(potassium ion transmembrane transport);GO:0086011(membrane repolarization during action potential);GO:0005546(phosphatidylinositol-4,5-bisphosphate binding);GO:0015467(G-protein activated inward rectifier potassium channel activity);GO:0014861(regulation of skeletal muscle contraction via regulation of action potential);GO:0060075(regulation of resting membrane potential);GO:0042802(identical protein binding);GO:0015693(magnesium ion transport);GO:0071260(cellular response to mechanical stimulus);GO:0086001(cardiac muscle cell action potential);GO:0086004(regulation of cardiac muscle cell contraction);GO:1901381(positive regulation of potassium ion transmembrane transport);GO:0005790(smooth endoplasmic reticulum);GO:0005791(rough endoplasmic reticulum);GO:0005794(Golgi apparatus);GO:0014704(intercalated disc);GO:0030315(T-tubule);GO:0030425(dendrite);GO:0043025(neuronal cell body);GO:0043197(dendritic spine);GO:0043197(dendritic spine)","04921(Oxytocin signaling pathway);04924(Renin secretion);04971(Gastric acid secretion);04725(Cholinergic synapse);04725(Cholinergic synapse)","K04996","NA","potassium voltage-gated channel subfamily J member 2 [Source:HGNC Symbol;Acc:HGNC:6263]",{"v":2.60721424708625,"d":"2.61"},{"v":5.41558299049668,"d":"5.42"},{"v":0.481428177106955,"d":"0.48"},{"v":-1.05460751231294,"d":"-1.05"},{"v":0.120646308044601,"d":"0.12"},{"v":0.902000685925924,"d":"0.90"},"down","no"]
["MSTRG.2434","SLC15A3","ENST00000541505;ENST00000227880;ENST00000543406;ENST00000538739;ENST00000536491;ENST00000536784;ENST00000537307;ENST00000540272;ENST00000544101","GO:0006810(transport);GO:0005215(transporter activity);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0015031(protein transport);GO:0043231(intracellular membrane-bounded organelle);GO:0005765(lysosomal membrane);GO:0015293(symporter activity);GO:0055085(transmembrane transport);GO:0005764(lysosome);GO:0015992(proton transport);GO:0015833(peptide transport);GO:0006811(ion transport);GO:0015333(peptide:proton symporter activity);GO:0015333(peptide:proton symporter activity)","NA","NA","NA","solute carrier family 15 member 3 [Source:HGNC Symbol;Acc:HGNC:18068]",{"v":5.11559801225891,"d":"5.12"},{"v":10.6131107633213,"d":"10.61"},{"v":0.482007408227408,"d":"0.48"},{"v":-1.05287277471675,"d":"-1.05"},{"v":0.120767283581974,"d":"0.12"},{"v":0.902000685925924,"d":"0.90"},"down","no"]
["ENSG00000133142","TCEAL4","ENST00000472484;ENST00000494801;ENST00000434216;ENST00000472745;ENST00000415568;ENST00000481555;ENST00000469586;ENST00000490644;ENST00000372629","GO:0005634(nucleus);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0050699(WW domain binding);GO:0003746(translation elongation factor activity);GO:0006414(translational elongation);GO:0006414(translational elongation)","NA","NA","NA","transcription elongation factor A like 4 [Source:HGNC Symbol;Acc:HGNC:26121]",{"v":2.73312932327244,"d":"2.73"},{"v":1.35630643328038,"d":"1.36"},{"v":2.0151267119349,"d":"2.02"},{"v":1.010870558819,"d":"1.01"},{"v":0.120824656846748,"d":"0.12"},{"v":0.902000685925924,"d":"0.90"},"up","no"]
["MSTRG.10410","RBFOX2","MSTRG.10410.1","NA","NA","NA","NA",null,{"v":97.675018,"d":"97.68"},{"v":48.82476,"d":"48.82"},{"v":2.00052223502993,"d":"2.00"},{"v":1.00037666376932,"d":"1.00"},{"v":0.120882747134842,"d":"0.12"},{"v":0.902000685925924,"d":"0.90"},"up","no"]
["MSTRG.12223","ST8SIA4","ENST00000451528;ENST00000231461;ENST00000507360;ENST00000523381","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016740(transferase activity);GO:0008373(sialyltransferase activity);GO:0016757(transferase activity, transferring glycosyl groups);GO:0006486(protein glycosylation);GO:0097503(sialylation);GO:0005794(Golgi apparatus);GO:0000139(Golgi membrane);GO:0007399(nervous system development);GO:0006464(cellular protein modification process);GO:0003828(alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity);GO:0033691(sialic acid binding);GO:0001574(ganglioside biosynthetic process);GO:0006491(N-glycan processing);GO:0009311(oligosaccharide metabolic process);GO:0009311(oligosaccharide metabolic process)","NA","NA","NA","ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4 [Source:HGNC Symbol;Acc:HGNC:10871]",{"v":6.99549507557095,"d":"7.00"},{"v":14.494568017321,"d":"14.49"},{"v":0.482628738380567,"d":"0.48"},{"v":-1.05101427074542,"d":"-1.05"},{"v":0.120902208411247,"d":"0.12"},{"v":0.902000685925924,"d":"0.90"},"down","no"]
["ENSG00000198225","FKBP1C","ENST00000370659","GO:0016853(isomerase activity);GO:0003755(peptidyl-prolyl cis-trans isomerase activity);GO:0000413(protein peptidyl-prolyl isomerization);GO:0005528(FK506 binding);GO:0061077(chaperone-mediated protein folding);GO:0005737(cytoplasm)","NA","NA","NA","FK506 binding protein 1C [Source:HGNC Symbol;Acc:HGNC:21376]",{"v":0.554983,"d":"0.55"},{"v":1.212158,"d":"1.21"},{"v":0.457847079341142,"d":"0.46"},{"v":-1.1270622754193,"d":"-1.13"},{"v":0.120928136060143,"d":"0.12"},{"v":0.902000685925924,"d":"0.90"},"down","no"]
["MSTRG.449","MACF1","ENST00000564288;ENST00000567887;ENST00000497964;ENST00000485063;ENST00000446276;ENST00000472385;ENST00000462496;ENST00000480624;ENST00000497807;ENST00000442046;ENST00000469490;ENST00000289893;ENST00000462103;ENST00000372925;ENST00000487656;ENST00000528611;ENST00000496360;ENST00000469366;ENST00000484793;MSTRG.449.17;ENST00000530275;ENST00000602421;ENST00000484393;ENST00000361689;ENST00000467673;ENST00000530262","GO:0003779(actin binding);GO:0005509(calcium ion binding);GO:0005856(cytoskeleton);GO:0008017(microtubule binding);GO:0016055(Wnt signaling pathway);GO:0016887(ATPase activity);GO:0003723(RNA binding);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0046872(metal ion binding);GO:0005794(Golgi apparatus);GO:0005886(plasma membrane);GO:0042995(cell projection);GO:0005515(protein binding);GO:0005874(microtubule);GO:0045296(cadherin binding);GO:0051015(actin filament binding);GO:0045773(positive regulation of axon extension);GO:0032587(ruffle membrane);GO:0042060(wound healing);GO:0051893(regulation of focal adhesion assembly);GO:0032886(regulation of microtubule-based process);GO:0030177(positive regulation of Wnt signaling pathway);GO:0010632(regulation of epithelial cell migration);GO:0043001(Golgi to plasma membrane protein transport);GO:0016021(integral component of membrane);GO:0030054(cell junction);GO:0015629(actin cytoskeleton);GO:0015629(actin cytoskeleton)","NA","NA","NA","microtubule-actin crosslinking factor 1 [Source:HGNC Symbol;Acc:HGNC:13664]",{"v":3.76921481010967,"d":"3.77"},{"v":1.88722318044619,"d":"1.89"},{"v":1.99722791091329,"d":"2.00"},{"v":0.997998973334228,"d":"1.00"},{"v":0.121052495217618,"d":"0.12"},{"v":0.902000685925924,"d":"0.90"},"up","no"]
["ENSG00000107779","BMPR1A","ENST00000372037;ENST00000635816;ENST00000480152","GO:0060045(positive regulation of cardiac muscle cell proliferation);GO:1904707(positive regulation of vascular smooth muscle cell proliferation);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0003151(outflow tract morphogenesis);GO:0030509(BMP signaling pathway);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0005515(protein binding);GO:0004702(signal transducer, downstream of receptor, with serine/threonine kinase activity);GO:0023014(signal transduction by protein phosphorylation);GO:0005886(plasma membrane);GO:0004675(transmembrane receptor protein serine/threonine kinase activity);GO:0007178(transmembrane receptor protein serine/threonine kinase signaling pathway);GO:0042803(protein homodimerization activity);GO:0009897(external side of plasma membrane);GO:0046332(SMAD binding);GO:0030501(positive regulation of bone mineralization);GO:0045669(positive regulation of osteoblast differentiation);GO:0071773(cellular response to BMP stimulus);GO:1990712(HFE-transferrin receptor complex);GO:0007179(transforming growth factor beta receptor signaling pathway);GO:0003148(outflow tract septum morphogenesis);GO:0003183(mitral valve morphogenesis);GO:0006955(immune response);GO:0005901(caveola);GO:0014912(negative regulation of smooth muscle cell migration);GO:0010862(positive regulation of pathway-restricted SMAD protein phosphorylation);GO:0060391(positive regulation of SMAD protein import into nucleus);GO:0003203(endocardial cushion morphogenesis);GO:0061312(BMP signaling pathway involved in heart development);GO:0061626(pharyngeal arch artery morphogenesis);GO:0003223(ventricular compact myocardium morphogenesis);GO:0003222(ventricular trabecula myocardium morphogenesis);GO:0035912(dorsal aorta morphogenesis);GO:0003272(endocardial cushion formation);GO:0098821(BMP receptor activity);GO:0003161(cardiac conduction system development);GO:0003186(tricuspid valve morphogenesis);GO:0003215(cardiac right ventricle morphogenesis);GO:0060043(regulation of cardiac muscle cell proliferation);GO:1904414(positive regulation of cardiac ventricle development);GO:1905285(fibrous ring of heart morphogenesis);GO:0000981(RNA polymerase II transcription factor activity, sequence-specific DNA binding);GO:0001701(in utero embryonic development);GO:0001707(mesoderm formation);GO:0001756(somitogenesis);GO:0001880(Mullerian duct regression);GO:0002053(positive regulation of mesenchymal cell proliferation);GO:0002062(chondrocyte differentiation);GO:0003007(heart morphogenesis);GO:0007389(pattern specification process);GO:0007398(ectoderm development);GO:0007399(nervous system development);GO:0007492(endoderm development);GO:0007507(heart development);GO:0009950(dorsal/ventral axis specification);GO:0009952(anterior/posterior pattern specification);GO:0009953(dorsal/ventral pattern formation);GO:0014032(neural crest cell development);GO:0019827(stem cell population maintenance);GO:0021983(pituitary gland development);GO:0021998(neural plate mediolateral regionalization);GO:0030154(cell differentiation);GO:0030324(lung development);GO:0035137(hindlimb morphogenesis);GO:0042475(odontogenesis of dentin-containing tooth);GO:0042733(embryonic digit morphogenesis);GO:0045893(positive regulation of transcription, DNA-templated);GO:0048339(paraxial mesoderm development);GO:0048352(paraxial mesoderm structural organization);GO:0048368(lateral mesoderm development);GO:0048378(regulation of lateral mesodermal cell fate specification);GO:0048382(mesendoderm development);GO:0048568(embryonic organ development);GO:0048589(developmental growth);GO:0048598(embryonic morphogenesis);GO:0050679(positive regulation of epithelial cell proliferation);GO:0050768(negative regulation of neurogenesis);GO:0051216(cartilage development);GO:0060021(palate development);GO:0060896(neural plate pattern specification);GO:0060914(heart formation);GO:1902895(positive regulation of pri-miRNA transcription from RNA polymerase II promoter);GO:2000772(regulation of cellular senescence);GO:0030425(dendrite);GO:0043025(neuronal cell body);GO:0043025(neuronal cell body)","04350(TGF-beta signaling pathway);04390(Hippo signaling pathway);04060(Cytokine-cytokine receptor interaction);04550(Signaling pathways regulating pluripotency of stem cells);05418(Fluid shear stress and atherosclerosis);05418(Fluid shear stress and atherosclerosis)","K04673","EC:2.7.11.30","bone morphogenetic protein receptor type 1A [Source:HGNC Symbol;Acc:HGNC:1076]",{"v":0.170392534174553,"d":"0.17"},{"v":0.0819167653347354,"d":"0.08"},{"v":2.08006912233754,"d":"2.08"},{"v":1.05663147105706,"d":"1.06"},{"v":0.12124326128934,"d":"0.12"},{"v":0.902000685925924,"d":"0.90"},"up","no"]
["MSTRG.8171","CEACAM4","ENST00000221954;MSTRG.8171.1;ENST00000472081","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005887(integral component of plasma membrane);GO:0006909(phagocytosis);GO:0006909(phagocytosis)","NA","NA","NA","carcinoembryonic antigen related cell adhesion molecule 4 [Source:HGNC Symbol;Acc:HGNC:1816]",{"v":6.79129368171621,"d":"6.79"},{"v":14.0781517420079,"d":"14.08"},{"v":0.482399522762041,"d":"0.48"},{"v":-1.05169961490719,"d":"-1.05"},{"v":0.121313381392622,"d":"0.12"},{"v":0.902000685925924,"d":"0.90"},"down","no"]
["ENSG00000169203","NPIPB12","ENST00000458643;ENST00000550690;ENST00000550665;ENST00000551448;ENST00000548346;ENST00000617311;ENST00000552123;ENST00000549733;ENST00000547235","GO:0005654(nucleoplasm);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016021(integral component of membrane)","NA","NA","NA","nuclear pore complex interacting protein family, member B12 [Source:HGNC Symbol;Acc:HGNC:37491]",{"v":1.52101451119834,"d":"1.52"},{"v":0.742849440775802,"d":"0.74"},{"v":2.0475407635898,"d":"2.05"},{"v":1.03389217413414,"d":"1.03"},{"v":0.121377241486055,"d":"0.12"},{"v":0.902000685925924,"d":"0.90"},"up","no"]
["ENSG00000120800","UTP20","ENST00000261637;ENST00000551825;ENST00000551998","GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005730(nucleolus);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0005654(nucleoplasm);GO:0006364(rRNA processing);GO:0000462(maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA));GO:0032040(small-subunit processome);GO:0008285(negative regulation of cell proliferation);GO:0030688(preribosome, small subunit precursor);GO:0030686(90S preribosome);GO:0000447(endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA));GO:0000472(endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA));GO:0000480(endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA));GO:0000480(endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA))","NA","NA","NA","UTP20, small subunit processome component [Source:HGNC Symbol;Acc:HGNC:17897]",{"v":1.13048118764964,"d":"1.13"},{"v":0.562797523443735,"d":"0.56"},{"v":2.00868188035418,"d":"2.01"},{"v":1.00624909917525,"d":"1.01"},{"v":0.12138402315762,"d":"0.12"},{"v":0.902000685925924,"d":"0.90"},"up","no"]
["MSTRG.3826","HCAR3;HCAR2","MSTRG.3826.2;MSTRG.3826.1;ENST00000528880;MSTRG.3826.3;ENST00000328880","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0004930(G-protein coupled receptor activity);GO:0007186(G-protein coupled receptor signaling pathway);GO:0005886(plasma membrane);GO:0030054(cell junction);GO:0004871(signal transducer activity);GO:0007165(signal transduction);GO:0005887(integral component of plasma membrane);GO:0006915(apoptotic process);GO:0001781(neutrophil apoptotic process);GO:0050995(negative regulation of lipid catabolic process);GO:0070553(nicotinic acid receptor activity);GO:0033031(positive regulation of neutrophil apoptotic process);GO:0070165(positive regulation of adiponectin secretion)","04024(cAMP signaling pathway);04024(cAMP signaling pathway)","K08402","NA","hydroxycarboxylic acid receptor 3 [Source:HGNC Symbol;Acc:HGNC:16824];hydroxycarboxylic acid receptor 2 [Source:HGNC Symbol;Acc:HGNC:24827]",{"v":11.5253383407879,"d":"11.53"},{"v":23.8622973596635,"d":"23.86"},{"v":0.482993660127217,"d":"0.48"},{"v":-1.04992384280986,"d":"-1.05"},{"v":0.12140193857715,"d":"0.12"},{"v":0.902000685925924,"d":"0.90"},"down","no"]
["MSTRG.5034","PATL2","ENST00000558159;ENST00000558809;ENST00000560780;ENST00000434130;ENST00000558573;ENST00000560775;ENST00000561082;ENST00000560110;ENST00000558481","GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0030529(intracellular ribonucleoprotein complex);GO:0005515(protein binding);GO:0000290(deadenylation-dependent decapping of nuclear-transcribed mRNA);GO:0017148(negative regulation of translation);GO:0033962(cytoplasmic mRNA processing body assembly);GO:0000932(P-body);GO:0010607(negative regulation of cytoplasmic mRNA processing body assembly);GO:0010607(negative regulation of cytoplasmic mRNA processing body assembly)","NA","NA","NA","PAT1 homolog 2 [Source:HGNC Symbol;Acc:HGNC:33630]",{"v":0.899443845315448,"d":"0.90"},{"v":0.444103239362817,"d":"0.44"},{"v":2.02530350061381,"d":"2.03"},{"v":1.01813811837814,"d":"1.02"},{"v":0.121463372876504,"d":"0.12"},{"v":0.902000685925924,"d":"0.90"},"up","no"]
["ENSG00000236438","FAM157A","ENST00000437428;ENST00000634862","NA","NA","NA","NA","family with sequence similarity 157 member A (non-protein coding) [Source:HGNC Symbol;Acc:HGNC:34079]",{"v":2.53005366929911,"d":"2.53"},{"v":5.24934673741362,"d":"5.25"},{"v":0.481974957239285,"d":"0.48"},{"v":-1.05296990694932,"d":"-1.05"},{"v":0.121558962146742,"d":"0.12"},{"v":0.902000685925924,"d":"0.90"},"down","no"]
["MSTRG.1791","MRPS16;DNAJC9","ENST00000372945;ENST00000372950;ENST00000453189;ENST00000372940;ENST00000471251;ENST00000512551;ENST00000473427;ENST00000469143;ENST00000479005","GO:0006412(translation);GO:0005829(cytosol);GO:0005739(mitochondrion);GO:0030529(intracellular ribonucleoprotein complex);GO:0005622(intracellular);GO:0003735(structural constituent of ribosome);GO:0005840(ribosome);GO:0032543(mitochondrial translation);GO:0005515(protein binding);GO:0005743(mitochondrial inner membrane);GO:0070125(mitochondrial translational elongation);GO:0070126(mitochondrial translational termination);GO:0005763(mitochondrial small ribosomal subunit);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005654(nucleoplasm);GO:0005886(plasma membrane);GO:0005615(extracellular space);GO:0032781(positive regulation of ATPase activity);GO:0035176(social behavior);GO:0031072(heat shock protein binding);GO:0005763(mitochondrial small ribosomal subunit)","03010(Ribosome);03010(Ribosome)","K02959","NA","mitochondrial ribosomal protein S16 [Source:HGNC Symbol;Acc:HGNC:14048];DnaJ heat shock protein family (Hsp40) member C9 [Source:HGNC Symbol;Acc:HGNC:19123]",{"v":3.31704106583445,"d":"3.32"},{"v":1.65653995110715,"d":"1.66"},{"v":2.00239122733955,"d":"2.00"},{"v":1.00172387557284,"d":"1.00"},{"v":0.121570097430475,"d":"0.12"},{"v":0.902000685925924,"d":"0.90"},"up","no"]
["MSTRG.9471","AC009950.1","ENST00000454058;ENST00000625295;ENST00000600787;ENST00000628587;ENST00000595586;ENST00000609120","NA","NA","NA","NA",null,{"v":0.982360516336369,"d":"0.98"},{"v":0.477721555704339,"d":"0.48"},{"v":2.05634538489268,"d":"2.06"},{"v":1.04008260072995,"d":"1.04"},{"v":0.12173035667578,"d":"0.12"},{"v":0.902282909729867,"d":"0.90"},"up","no"]
["MSTRG.9546","FKBP1A;SDCBP2;AL136531.2","ENST00000474657;ENST00000400137;ENST00000618612;ENST00000381719;ENST00000467129;ENST00000474726;ENST00000381724;ENST00000360779;ENST00000381808;ENST00000381715;ENST00000460490;ENST00000614856;ENST00000439640;ENST00000618770;ENST00000615838;ENST00000381812;ENST00000617804;ENST00000612074","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0016853(isomerase activity);GO:0005829(cytosol);GO:0003755(peptidyl-prolyl cis-trans isomerase activity);GO:0005515(protein binding);GO:0004871(signal transducer activity);GO:0061077(chaperone-mediated protein folding);GO:0070062(extracellular exosome);GO:0016529(sarcoplasmic reticulum);GO:0006457(protein folding);GO:0043123(positive regulation of I-kappaB kinase/NF-kappaB signaling);GO:0044325(ion channel binding);GO:0033017(sarcoplasmic reticulum membrane);GO:0032092(positive regulation of protein binding);GO:0030018(Z disc);GO:0097435(supramolecular fiber organization);GO:0034713(type I transforming growth factor beta receptor binding);GO:0048185(activin binding);GO:0031398(positive regulation of protein ubiquitination);GO:0032925(regulation of activin receptor signaling pathway);GO:0055010(ventricular cardiac muscle tissue morphogenesis);GO:0046332(SMAD binding);GO:0003007(heart morphogenesis);GO:0032880(regulation of protein localization);GO:0022417(protein maturation by protein folding);GO:0060347(heart trabecula formation);GO:0007179(transforming growth factor beta receptor signaling pathway);GO:0007183(SMAD protein complex assembly);GO:0042026(protein refolding);GO:0006458('de novo' protein folding);GO:0060314(regulation of ryanodine-sensitive calcium-release channel activity);GO:0070588(calcium ion transmembrane transport);GO:0014802(terminal cisterna);GO:1990425(ryanodine receptor complex);GO:0005160(transforming growth factor beta receptor binding);GO:0005527(macrolide binding);GO:0005528(FK506 binding);GO:0008144(drug binding);GO:0019899(enzyme binding);GO:0030544(Hsp70 protein binding);GO:0042803(protein homodimerization activity);GO:0000413(protein peptidyl-prolyl isomerization);GO:0001933(negative regulation of protein phosphorylation);GO:0006936(muscle contraction);GO:0010039(response to iron ion);GO:0019221(cytokine-mediated signaling pathway);GO:0031000(response to caffeine);GO:0032515(negative regulation of phosphoprotein phosphatase activity);GO:0042098(T cell proliferation);GO:0042110(T cell activation);GO:0050776(regulation of immune response);GO:0051209(release of sequestered calcium ion into cytosol);GO:1902991(regulation of amyloid precursor protein catabolic process);GO:1990000(amyloid fibril formation);GO:0031312(extrinsic component of organelle membrane);GO:0043231(intracellular membrane-bounded organelle);GO:0043679(axon terminus);GO:0098562(cytoplasmic side of membrane);GO:0016021(integral component of membrane);GO:0005886(plasma membrane);GO:0007399(nervous system development);GO:0042802(identical protein binding);GO:0008022(protein C-terminus binding);GO:0046982(protein heterodimerization activity);GO:0035556(intracellular signal transduction);GO:0046907(intracellular transport);GO:0016021(integral component of membrane)","NA","NA","NA","FK506 binding protein 1A [Source:HGNC Symbol;Acc:HGNC:3711];syndecan binding protein 2 [Source:HGNC Symbol;Acc:HGNC:15756]",{"v":16.5781208816769,"d":"16.58"},{"v":34.2948562874717,"d":"34.29"},{"v":0.483399631207467,"d":"0.48"},{"v":-1.04871172243625,"d":"-1.05"},{"v":0.121757991057219,"d":"0.12"},{"v":0.902282909729867,"d":"0.90"},"down","no"]
["MSTRG.14350","PCMTD1","ENST00000522514;ENST00000360540;MSTRG.14350.4;ENST00000521344;ENST00000519975;ENST00000519554;ENST00000521046;ENST00000544451;ENST00000519559","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0006464(cellular protein modification process);GO:0032259(methylation);GO:0004719(protein-L-isoaspartate (D-aspartate) O-methyltransferase activity);GO:0006479(protein methylation);GO:0006479(protein methylation)","NA","NA","NA","protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 1 [Source:HGNC Symbol;Acc:HGNC:30483]",{"v":1.92988717185367,"d":"1.93"},{"v":4.00056402552553,"d":"4.00"},{"v":0.48240377095331,"d":"0.48"},{"v":-1.05168691004908,"d":"-1.05"},{"v":0.121905948309245,"d":"0.12"},{"v":0.902823403591865,"d":"0.90"},"down","no"]
["ENSG00000184307","ZDHHC23","ENST00000638807;ENST00000330212;ENST00000478793;ENST00000488129;ENST00000491556","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016740(transferase activity);GO:0016746(transferase activity, transferring acyl groups);GO:0019706(protein-cysteine S-palmitoyltransferase activity);GO:0018345(protein palmitoylation);GO:0072659(protein localization to plasma membrane);GO:0072659(protein localization to plasma membrane)","NA","NA","NA","zinc finger DHHC-type containing 23 [Source:HGNC Symbol;Acc:HGNC:28654]",{"v":0.299760987951807,"d":"0.30"},{"v":0.142472715606612,"d":"0.14"},{"v":2.10398872988068,"d":"2.10"},{"v":1.07312697678383,"d":"1.07"},{"v":0.121980873413383,"d":"0.12"},{"v":0.902823403591865,"d":"0.90"},"up","no"]
["MSTRG.1318","LINC01136","ENST00000457348;ENST00000425698;ENST00000432511","NA","NA","NA","NA","long intergenic non-protein coding RNA 1136 [Source:HGNC Symbol;Acc:HGNC:49452]",{"v":0.23475159853211,"d":"0.23"},{"v":0.51552696,"d":"0.52"},{"v":0.455362409236774,"d":"0.46"},{"v":-1.1349128948623,"d":"-1.13"},{"v":0.122233102142958,"d":"0.12"},{"v":0.904020768887551,"d":"0.90"},"down","no"]
["MSTRG.5795","AC009133.3","ENST00000565600","NA","NA","NA","NA",null,{"v":0.390525,"d":"0.39"},{"v":0.867312,"d":"0.87"},{"v":0.45027049089601,"d":"0.45"},{"v":-1.15113616313917,"d":"-1.15"},{"v":0.122360930730826,"d":"0.12"},{"v":0.904020768887551,"d":"0.90"},"down","no"]
["ENSG00000169359","SLC33A1","ENST00000392845;ENST00000460729;ENST00000496772;ENST00000359479;ENST00000468581","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0015992(proton transport);GO:0055085(transmembrane transport);GO:0030509(BMP signaling pathway);GO:0005887(integral component of plasma membrane);GO:0008521(acetyl-CoA transporter activity);GO:0015876(acetyl-CoA transport);GO:0015295(solute:proton symporter activity);GO:0060395(SMAD protein signal transduction);GO:0000139(Golgi membrane);GO:0000139(Golgi membrane)","00604(Glycosphingolipid biosynthesis - ganglio series);00604(Glycosphingolipid biosynthesis - ganglio series)","K03372","EC:2.3.1.-","solute carrier family 33 member 1 [Source:HGNC Symbol;Acc:HGNC:95]",{"v":1.06599473262699,"d":"1.07"},{"v":0.531001780097642,"d":"0.53"},{"v":2.00751630706581,"d":"2.01"},{"v":1.0054117068098,"d":"1.01"},{"v":0.122398058394732,"d":"0.12"},{"v":0.904020768887551,"d":"0.90"},"up","no"]
["ENSG00000136603","SKIL","ENST00000458537;ENST00000490989;ENST00000259119;ENST00000470571;ENST00000413427;ENST00000477216;ENST00000465590","GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0046332(SMAD binding);GO:0030512(negative regulation of transforming growth factor beta receptor signaling pathway);GO:0005515(protein binding);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:0001078(transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0005654(nucleoplasm);GO:0043234(protein complex);GO:0048666(neuron development);GO:0030514(negative regulation of BMP signaling pathway);GO:0045596(negative regulation of cell differentiation);GO:0003682(chromatin binding);GO:0001825(blastocyst formation);GO:0002260(lymphocyte homeostasis);GO:0007050(cell cycle arrest);GO:0007179(transforming growth factor beta receptor signaling pathway);GO:0007283(spermatogenesis);GO:0034097(response to cytokine);GO:0050772(positive regulation of axonogenesis);GO:0070306(lens fiber cell differentiation);GO:1902043(positive regulation of extrinsic apoptotic signaling pathway via death domain receptors);GO:1902231(positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage);GO:0001669(acrosomal vesicle);GO:0005634(nucleus);GO:0005634(nucleus)","04550(Signaling pathways regulating pluripotency of stem cells);04550(Signaling pathways regulating pluripotency of stem cells)","K18499","NA","SKI like proto-oncogene [Source:HGNC Symbol;Acc:HGNC:10897]",{"v":0.829446104086353,"d":"0.83"},{"v":1.72491971896685,"d":"1.72"},{"v":0.480860700336335,"d":"0.48"},{"v":-1.05630907207714,"d":"-1.06"},{"v":0.122517109762929,"d":"0.12"},{"v":0.904020768887551,"d":"0.90"},"down","no"]
["ENSG00000198420","TCAF1","ENST00000479870;ENST00000478172;ENST00000392900;ENST00000355951","GO:0006810(transport);GO:0016020(membrane);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0044325(ion channel binding);GO:0090314(positive regulation of protein targeting to membrane);GO:0030336(negative regulation of cell migration);GO:1901529(positive regulation of anion channel activity);GO:1901529(positive regulation of anion channel activity)","NA","NA","NA","TRPM8 channel associated factor 1 [Source:HGNC Symbol;Acc:HGNC:22201]",{"v":1.22161585293185,"d":"1.22"},{"v":0.609775913470681,"d":"0.61"},{"v":2.00338489262185,"d":"2.00"},{"v":1.00243962001863,"d":"1.00"},{"v":0.122518011528358,"d":"0.12"},{"v":0.904020768887551,"d":"0.90"},"up","no"]
["MSTRG.4450","DHRS7","ENST00000611054;ENST00000554101;ENST00000555171;ENST00000556502;ENST00000553986;ENST00000557751;ENST00000536410;ENST00000216500;ENST00000557137","GO:0016020(membrane);GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0055114(oxidation-reduction process)","NA","NA","NA","dehydrogenase/reductase 7 [Source:HGNC Symbol;Acc:HGNC:21524]",{"v":9.75385846767241,"d":"9.75"},{"v":20.173506578202,"d":"20.17"},{"v":0.483498415600772,"d":"0.48"},{"v":-1.04841693281431,"d":"-1.05"},{"v":0.122648888293842,"d":"0.12"},{"v":0.904174054775771,"d":"0.90"},"down","no"]
["ENSG00000150347","ARID5B","ENST00000279873;ENST00000309334","GO:0005634(nucleus);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0003713(transcription coactivator activity);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0005654(nucleoplasm);GO:0060612(adipose tissue development);GO:0044212(transcription regulatory region DNA binding);GO:0051091(positive regulation of sequence-specific DNA binding transcription factor activity);GO:0000977(RNA polymerase II regulatory region sequence-specific DNA binding);GO:0032452(histone demethylase activity);GO:0001227(transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding);GO:0001889(liver development);GO:0045892(negative regulation of transcription, DNA-templated);GO:0001822(kidney development);GO:0006807(nitrogen compound metabolic process);GO:0008584(male gonad development);GO:0008585(female gonad development);GO:0009791(post-embryonic development);GO:0010761(fibroblast migration);GO:0016577(histone demethylation);GO:0030325(adrenal gland development);GO:0035264(multicellular organism growth);GO:0045444(fat cell differentiation);GO:0048008(platelet-derived growth factor receptor signaling pathway);GO:0048468(cell development);GO:0048644(muscle organ morphogenesis);GO:0048705(skeletal system morphogenesis);GO:0060021(palate development);GO:0060325(face morphogenesis);GO:0060613(fat pad development);GO:1990830(cellular response to leukemia inhibitory factor);GO:1990830(cellular response to leukemia inhibitory factor)","NA","NA","NA","AT-rich interaction domain 5B [Source:HGNC Symbol;Acc:HGNC:17362]",{"v":0.702570544341009,"d":"0.70"},{"v":1.45992146643802,"d":"1.46"},{"v":0.481238587480442,"d":"0.48"},{"v":-1.05517576713916,"d":"-1.06"},{"v":0.122715331478397,"d":"0.12"},{"v":0.904174054775771,"d":"0.90"},"down","no"]
["ENSG00000163535","SGO2","ENST00000357799;ENST00000488636","GO:0000775(chromosome, centromeric region);GO:0051754(meiotic sister chromatid cohesion, centromeric);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0051301(cell division);GO:0005694(chromosome);GO:0005515(protein binding);GO:0007049(cell cycle);GO:0016604(nuclear body);GO:0051321(meiotic cell cycle);GO:0007059(chromosome segregation);GO:0000776(kinetochore);GO:0000777(condensed chromosome kinetochore);GO:0005829(cytosol);GO:0007062(sister chromatid cohesion);GO:0030892(mitotic cohesin complex);GO:0030892(mitotic cohesin complex)","NA","NA","NA","shugoshin 2 [Source:HGNC Symbol;Acc:HGNC:30812]",{"v":0.113809770508137,"d":"0.11"},{"v":0.254317909000332,"d":"0.25"},{"v":0.447509854714905,"d":"0.45"},{"v":-1.16000864224951,"d":"-1.16"},{"v":0.122830598189384,"d":"0.12"},{"v":0.904174054775771,"d":"0.90"},"down","no"]
["MSTRG.13649","CHCHD2","ENST00000395422;ENST00000473095","GO:0005634(nucleus);GO:0006351(transcription, DNA-templated);GO:0005739(mitochondrion);GO:0005515(protein binding);GO:0005758(mitochondrial intermembrane space);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0043565(sequence-specific DNA binding);GO:0008134(transcription factor binding);GO:1900037(regulation of cellular response to hypoxia);GO:0007005(mitochondrion organization);GO:0007005(mitochondrion organization)","NA","NA","NA","coiled-coil-helix-coiled-coil-helix domain containing 2 [Source:HGNC Symbol;Acc:HGNC:21645]",{"v":11.9357212464664,"d":"11.94"},{"v":24.7075586519435,"d":"24.71"},{"v":0.483079749586167,"d":"0.48"},{"v":-1.04966671776205,"d":"-1.05"},{"v":0.122873928608794,"d":"0.12"},{"v":0.904174054775771,"d":"0.90"},"down","no"]
["MSTRG.8978","ANKRD23","MSTRG.8978.1","NA","NA","NA","NA",null,{"v":12.20753,"d":"12.21"},{"v":5.973018,"d":"5.97"},{"v":2.04377920843366,"d":"2.04"},{"v":1.031239348867,"d":"1.03"},{"v":0.123021476799945,"d":"0.12"},{"v":0.904174054775771,"d":"0.90"},"up","no"]
["ENSG00000214967","NPIPA7","ENST00000344087;ENST00000530217","GO:0005654(nucleoplasm);GO:0005515(protein binding);GO:0005515(protein binding)","NA","NA","NA","nuclear pore complex interacting protein family member A7 [Source:HGNC Symbol;Acc:HGNC:41982]",{"v":1.12106100356888,"d":"1.12"},{"v":0.532049052105639,"d":"0.53"},{"v":2.10706324751856,"d":"2.11"},{"v":1.07523362004601,"d":"1.08"},{"v":0.123144532660314,"d":"0.12"},{"v":0.904174054775771,"d":"0.90"},"up","no"]
["MSTRG.446","BMP8B","ENST00000372827","GO:0008083(growth factor activity);GO:0005576(extracellular region);GO:0007275(multicellular organism development);GO:0005125(cytokine activity);GO:0005615(extracellular space);GO:0030154(cell differentiation);GO:0060395(SMAD protein signal transduction);GO:0001503(ossification);GO:0051216(cartilage development);GO:0005160(transforming growth factor beta receptor binding);GO:0010862(positive regulation of pathway-restricted SMAD protein phosphorylation);GO:0030509(BMP signaling pathway);GO:0042981(regulation of apoptotic process);GO:0043408(regulation of MAPK cascade);GO:0048468(cell development);GO:0001501(skeletal system development);GO:0070700(BMP receptor binding)","04350(TGF-beta signaling pathway);04390(Hippo signaling pathway)","K16622","NA","bone morphogenetic protein 8b [Source:HGNC Symbol;Acc:HGNC:1075]",{"v":0.730926,"d":"0.73"},{"v":0.357329,"d":"0.36"},{"v":2.04552667149881,"d":"2.05"},{"v":1.03247234856217,"d":"1.03"},{"v":0.123152684798153,"d":"0.12"},{"v":0.904174054775771,"d":"0.90"},"up","no"]
["MSTRG.3423","ITGA5","ENST00000552387;ENST00000293379;ENST00000547744;ENST00000550141;ENST00000553071;ENST00000552564;ENST00000549601;ENST00000552583;ENST00000551861;ENST00000435631;ENST00000552431;ENST00000551564","GO:1903672(positive regulation of sprouting angiogenesis);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0046872(metal ion binding);GO:0007155(cell adhesion);GO:0005515(protein binding);GO:0030054(cell junction);GO:0007229(integrin-mediated signaling pathway);GO:0008305(integrin complex);GO:0005925(focal adhesion);GO:0050900(leukocyte migration);GO:0005886(plasma membrane);GO:0046718(viral entry into host cell);GO:0016032(viral process);GO:0050731(positive regulation of peptidyl-tyrosine phosphorylation);GO:0009986(cell surface);GO:0030198(extracellular matrix organization);GO:0001726(ruffle);GO:0001525(angiogenesis);GO:0005911(cell-cell junction);GO:0001618(virus receptor activity);GO:0031589(cell-substrate adhesion);GO:0043184(vascular endothelial growth factor receptor 2 binding);GO:0005161(platelet-derived growth factor receptor binding);GO:0032587(ruffle membrane);GO:0030949(positive regulation of vascular endothelial growth factor receptor signaling pathway);GO:0035987(endodermal cell differentiation);GO:0071062(alphav-beta3 integrin-vitronectin complex);GO:0033627(cell adhesion mediated by integrin);GO:0034113(heterotypic cell-cell adhesion);GO:2000811(negative regulation of anoikis);GO:0005154(epidermal growth factor receptor binding);GO:0005178(integrin binding);GO:0050839(cell adhesion molecule binding);GO:0007044(cell-substrate junction assembly);GO:0007157(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules);GO:0007159(leukocyte cell-cell adhesion);GO:0007613(memory);GO:0010811(positive regulation of cell-substrate adhesion);GO:0030335(positive regulation of cell migration);GO:0033631(cell-cell adhesion mediated by integrin);GO:0035313(wound healing, spreading of epidermal cells);GO:0045765(regulation of angiogenesis);GO:0005737(cytoplasm);GO:0005783(endoplasmic reticulum);GO:0005794(Golgi apparatus);GO:0009897(external side of plasma membrane);GO:0031410(cytoplasmic vesicle);GO:0045202(synapse);GO:0045202(synapse)","04151(PI3K-Akt signaling pathway);04512(ECM-receptor interaction);04145(Phagosome);04510(Focal adhesion);04810(Regulation of actin cytoskeleton);04640(Hematopoietic cell lineage);05206(MicroRNAs in cancer);05205(Proteoglycans in cancer);05410(Hypertrophic cardiomyopathy (HCM));05412(Arrhythmogenic right ventricular cardiomyopathy (ARVC));05414(Dilated cardiomyopathy (DCM));05131(Shigellosis);05133(Pertussis);05100(Bacterial invasion of epithelial cells);05165(Human papillomavirus infection);05165(Human papillomavirus infection)","K06484","NA","integrin subunit alpha 5 [Source:HGNC Symbol;Acc:HGNC:6141]",{"v":10.975520298799,"d":"10.98"},{"v":22.6375028758084,"d":"22.64"},{"v":0.484837941667497,"d":"0.48"},{"v":-1.04442549155159,"d":"-1.04"},{"v":0.123162675817276,"d":"0.12"},{"v":0.904174054775771,"d":"0.90"},"down","no"]
["MSTRG.12882","LSM2","ENST00000375661;ENST00000470083;ENST00000470086;ENST00000491421;ENST00000475835","GO:0003723(RNA binding);GO:0006397(mRNA processing);GO:0008380(RNA splicing);GO:0005634(nucleus);GO:0030529(intracellular ribonucleoprotein complex);GO:0005515(protein binding);GO:0005681(spliceosomal complex);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0000398(mRNA splicing, via spliceosome);GO:0000932(P-body);GO:0046540(U4/U6 x U5 tri-snRNP complex);GO:0017160(Ral GTPase binding);GO:0043928(exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay);GO:1990726(Lsm1-7-Pat1 complex);GO:0071013(catalytic step 2 spliceosome);GO:0071011(precatalytic spliceosome);GO:0017070(U6 snRNA binding);GO:0005688(U6 snRNP);GO:0005688(U6 snRNP)","03040(Spliceosome);03018(RNA degradation);03018(RNA degradation)","K12621","NA","LSM2 homolog, U6 small nuclear RNA and mRNA degradation associated [Source:HGNC Symbol;Acc:HGNC:13940]",{"v":8.07108898792943,"d":"8.07"},{"v":4.01162763231198,"d":"4.01"},{"v":2.01192376952442,"d":"2.01"},{"v":1.00857564340758,"d":"1.01"},{"v":0.123278737935548,"d":"0.12"},{"v":0.904174054775771,"d":"0.90"},"up","no"]
["ENSG00000115594","IL1R1","ENST00000410023;ENST00000450319;ENST00000452403;ENST00000424272;ENST00000409589;ENST00000430171;ENST00000428279","GO:0004909(interleukin-1, Type I, activating receptor activity);GO:0070498(interleukin-1-mediated signaling pathway);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0043231(intracellular membrane-bounded organelle);GO:0007165(signal transduction);GO:0019221(cytokine-mediated signaling pathway);GO:0004908(interleukin-1 receptor activity);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0005887(integral component of plasma membrane);GO:0004871(signal transducer activity);GO:0006955(immune response);GO:0007166(cell surface receptor signaling pathway);GO:0004888(transmembrane signaling receptor activity);GO:0070555(response to interleukin-1);GO:0005161(platelet-derived growth factor receptor binding);GO:0002020(protease binding);GO:0019966(interleukin-1 binding);GO:0050727(regulation of inflammatory response);GO:2000391(positive regulation of neutrophil extravasation);GO:2000661(positive regulation of interleukin-1-mediated signaling pathway);GO:0009986(cell surface);GO:0009986(cell surface)","04010(MAPK signaling pathway);04064(NF-kappa B signaling pathway);04060(Cytokine-cytokine receptor interaction);04640(Hematopoietic cell lineage);04659(Th17 cell differentiation);04750(Inflammatory mediator regulation of TRP channels);04380(Osteoclast differentiation);05418(Fluid shear stress and atherosclerosis);05166(HTLV-I infection);05146(Amoebiasis);05146(Amoebiasis)","K04386","NA","interleukin 1 receptor type 1 [Source:HGNC Symbol;Acc:HGNC:5993]",{"v":0.605235907666243,"d":"0.61"},{"v":1.25951851800085,"d":"1.26"},{"v":0.480529582547856,"d":"0.48"},{"v":-1.05730284540475,"d":"-1.06"},{"v":0.123329195447153,"d":"0.12"},{"v":0.904174054775771,"d":"0.90"},"down","no"]
["ENSG00000187792","ZNF70","ENST00000341976","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding)","NA","NA","NA","zinc finger protein 70 [Source:HGNC Symbol;Acc:HGNC:13140]",{"v":0.534487,"d":"0.53"},{"v":0.262625,"d":"0.26"},{"v":2.03517182294146,"d":"2.04"},{"v":1.02515060168615,"d":"1.03"},{"v":0.123439198506508,"d":"0.12"},{"v":0.904174054775771,"d":"0.90"},"up","no"]
["MSTRG.13666","KCTD7;RABGEF1","ENST00000639828;ENST00000450873;ENST00000638540;ENST00000639879;ENST00000461017;ENST00000437078;ENST00000640851;ENST00000638524;ENST00000442563;ENST00000275532;ENST00000607882;ENST00000640385;ENST00000284957;ENST00000640234;ENST00000449064;ENST00000503687","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005829(cytosol);GO:0051260(protein homooligomerization);GO:0005886(plasma membrane);GO:0043687(post-translational protein modification);GO:0008270(zinc ion binding);GO:0003677(DNA binding);GO:0006810(transport);GO:0015031(protein transport);GO:0046872(metal ion binding);GO:0005730(nucleolus);GO:0016567(protein ubiquitination);GO:0043547(positive regulation of GTPase activity);GO:0005515(protein binding);GO:0005768(endosome);GO:0006897(endocytosis);GO:0017112(Rab guanyl-nucleotide exchange factor activity);GO:0061024(membrane organization);GO:0005769(early endosome);GO:0055037(recycling endosome);GO:0006612(protein targeting to membrane);GO:0017137(Rab GTPase binding);GO:0031901(early endosome membrane);GO:0003677(DNA binding)","NA","NA","NA","potassium channel tetramerization domain containing 7 [Source:HGNC Symbol;Acc:HGNC:21957];RAB guanine nucleotide exchange factor 1 [Source:HGNC Symbol;Acc:HGNC:17676]",{"v":1.26122405995004,"d":"1.26"},{"v":2.60866246847324,"d":"2.61"},{"v":0.483475372989972,"d":"0.48"},{"v":-1.04848569054225,"d":"-1.05"},{"v":0.123558985568168,"d":"0.12"},{"v":0.904174054775771,"d":"0.90"},"down","no"]
["MSTRG.5884","AC135050.6","ENST00000610813;ENST00000613584","NA","NA","NA","NA",null,{"v":1.05128431746032,"d":"1.05"},{"v":2.28055621164021,"d":"2.28"},{"v":0.460977156403534,"d":"0.46"},{"v":-1.11723283481821,"d":"-1.12"},{"v":0.123607360361336,"d":"0.12"},{"v":0.904174054775771,"d":"0.90"},"down","no"]
["ENSG00000234614","AL450992.2","ENST00000434182","NA","NA","NA","NA",null,{"v":3.367683,"d":"3.37"},{"v":1.609643,"d":"1.61"},{"v":2.09219249237253,"d":"2.09"},{"v":1.06501559298811,"d":"1.07"},{"v":0.123607360361336,"d":"0.12"},{"v":0.904174054775771,"d":"0.90"},"up","no"]
["ENSG00000167747","C19orf48","ENST00000597493;ENST00000598463;ENST00000601267;ENST00000596554;ENST00000641834;ENST00000391812;ENST00000593287;ENST00000596655;ENST00000596287;ENST00000641539;ENST00000595794;ENST00000345523","NA","NA","NA","NA","chromosome 19 open reading frame 48 [Source:HGNC Symbol;Acc:HGNC:29667]",{"v":1.16359364588452,"d":"1.16"},{"v":0.567823253071253,"d":"0.57"},{"v":2.04921802619187,"d":"2.05"},{"v":1.0350734878007,"d":"1.04"},{"v":0.123665061303413,"d":"0.12"},{"v":0.904174054775771,"d":"0.90"},"up","no"]
["ENSG00000171916","LGALS9C","ENST00000583322;ENST00000577691;ENST00000577265;ENST00000582928;ENST00000328114;ENST00000578563;ENST00000578983;ENST00000584127;ENST00000579773;ENST00000584170;ENST00000578450","GO:0030246(carbohydrate binding);GO:0005829(cytosol);GO:0005515(protein binding);GO:0005515(protein binding)","NA","NA","NA","galectin 9C [Source:HGNC Symbol;Acc:HGNC:33874]",{"v":0.822222820992848,"d":"0.82"},{"v":0.398791810054691,"d":"0.40"},{"v":2.06178462110365,"d":"2.06"},{"v":1.04389363324205,"d":"1.04"},{"v":0.123840874416984,"d":"0.12"},{"v":0.904910078719252,"d":"0.90"},"up","no"]
["MSTRG.8155","COQ8B","ENST00000593544;ENST00000601451;ENST00000593723;ENST00000243583;ENST00000594490;ENST00000599643;ENST00000595254;ENST00000601304;ENST00000596455;ENST00000324464;ENST00000594720;ENST00000593724;ENST00000601967","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0005739(mitochondrion);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0006744(ubiquinone biosynthetic process);GO:0031966(mitochondrial membrane);GO:0021692(cerebellar Purkinje cell layer morphogenesis);GO:0021692(cerebellar Purkinje cell layer morphogenesis)","NA","NA","NA","coenzyme Q8B [Source:HGNC Symbol;Acc:HGNC:19041]",{"v":0.963133852951895,"d":"0.96"},{"v":2.01604336297376,"d":"2.02"},{"v":0.477734690949914,"d":"0.48"},{"v":-1.06571845223306,"d":"-1.07"},{"v":0.123940957134773,"d":"0.12"},{"v":0.905092180604572,"d":"0.91"},"down","no"]
["ENSG00000233024","AC126755.2","ENST00000546267;ENST00000427999;ENST00000526166;ENST00000543228;ENST00000545114;ENST00000528301;ENST00000533010","GO:0005654(nucleoplasm);GO:0005654(nucleoplasm)","NA","NA","NA","nuclear pore complex-interacting protein family member A5 isoform 2  [Source:RefSeq peptide;Acc:NP_001338129]",{"v":1.73884670858086,"d":"1.74"},{"v":0.851065655115512,"d":"0.85"},{"v":2.04314050053501,"d":"2.04"},{"v":1.03078841721623,"d":"1.03"},{"v":0.124093539218382,"d":"0.12"},{"v":0.905375009322596,"d":"0.91"},"up","no"]
["MSTRG.14216","AC037459.2","ENST00000514980","NA","NA","NA","NA",null,{"v":0.458027,"d":"0.46"},{"v":0.218858,"d":"0.22"},{"v":2.09280446682324,"d":"2.09"},{"v":1.06543752519981,"d":"1.07"},{"v":0.124153349435628,"d":"0.12"},{"v":0.905375009322596,"d":"0.91"},"up","no"]
["MSTRG.10423","TST","ENST00000249042;ENST00000403892","GO:0003723(RNA binding);GO:0016740(transferase activity);GO:0005739(mitochondrion);GO:0005615(extracellular space);GO:0005759(mitochondrial matrix);GO:0004792(thiosulfate sulfurtransferase activity);GO:0070062(extracellular exosome);GO:0030855(epithelial cell differentiation);GO:0009440(cyanate catabolic process);GO:0008097(5S rRNA binding);GO:0035928(rRNA import into mitochondrion);GO:0051029(rRNA transport);GO:0005743(mitochondrial inner membrane);GO:0005743(mitochondrial inner membrane)","00920(Sulfur metabolism);00270(Cysteine and methionine metabolism);04122(Sulfur relay system);04122(Sulfur relay system)","K01011","EC:2.8.1.1;EC:2.8.1.2","thiosulfate sulfurtransferase [Source:HGNC Symbol;Acc:HGNC:12388]",{"v":1.67775322096025,"d":"1.68"},{"v":3.49500242798141,"d":"3.50"},{"v":0.480043506558953,"d":"0.48"},{"v":-1.05876293102758,"d":"-1.06"},{"v":0.124239357605208,"d":"0.12"},{"v":0.905375009322596,"d":"0.91"},"down","no"]
["MSTRG.4849","IGHV3-53","ENST00000390627","GO:0016020(membrane);GO:0005886(plasma membrane);GO:0005576(extracellular region);GO:0006508(proteolysis);GO:0006955(immune response);GO:0002376(immune system process);GO:0003823(antigen binding);GO:0002250(adaptive immune response);GO:0004252(serine-type endopeptidase activity);GO:0006898(receptor-mediated endocytosis);GO:0006956(complement activation);GO:0006958(complement activation, classical pathway);GO:0030449(regulation of complement activation);GO:0038095(Fc-epsilon receptor signaling pathway);GO:0038096(Fc-gamma receptor signaling pathway involved in phagocytosis);GO:0050776(regulation of immune response);GO:0050900(leukocyte migration)","NA","NA","NA","immunoglobulin heavy variable 3-53 [Source:HGNC Symbol;Acc:HGNC:5610]",{"v":3.387193,"d":"3.39"},{"v":1.656895,"d":"1.66"},{"v":2.0443015399286,"d":"2.04"},{"v":1.03160801333717,"d":"1.03"},{"v":0.124357801301867,"d":"0.12"},{"v":0.905375009322596,"d":"0.91"},"up","no"]
["MSTRG.3941","USPL1","ENST00000255304;ENST00000465952","GO:0005634(nucleus);GO:0016787(hydrolase activity);GO:0005515(protein binding);GO:0008233(peptidase activity);GO:0008234(cysteine-type peptidase activity);GO:0006508(proteolysis);GO:0005615(extracellular space);GO:0030576(Cajal body organization);GO:0008283(cell proliferation);GO:0015030(Cajal body);GO:0032183(SUMO binding);GO:0070140(SUMO-specific isopeptidase activity);GO:0016926(protein desumoylation);GO:0016926(protein desumoylation)","NA","NA","NA","ubiquitin specific peptidase like 1 [Source:HGNC Symbol;Acc:HGNC:20294]",{"v":2.12717493678049,"d":"2.13"},{"v":1.06387157853659,"d":"1.06"},{"v":1.9994658939066,"d":"2.00"},{"v":0.999614672440133,"d":"1.00"},{"v":0.124527283868525,"d":"0.12"},{"v":0.905375009322596,"d":"0.91"},"up","no"]
["MSTRG.11564","RELL1","MSTRG.11564.1","NA","NA","NA","NA",null,{"v":2.6961,"d":"2.70"},{"v":5.596586,"d":"5.60"},{"v":0.481740117993362,"d":"0.48"},{"v":-1.05367302228062,"d":"-1.05"},{"v":0.124596080592929,"d":"0.12"},{"v":0.905375009322596,"d":"0.91"},"down","no"]
["ENSG00000230383","AC009245.1","ENST00000456481","NA","NA","NA","NA",null,{"v":3.823283,"d":"3.82"},{"v":1.885616,"d":"1.89"},{"v":2.02760424179685,"d":"2.03"},{"v":1.01977608719591,"d":"1.02"},{"v":0.124609992356868,"d":"0.12"},{"v":0.905375009322596,"d":"0.91"},"up","no"]
["MSTRG.9692","MMP24-AS1;EIF6;AL121753.1","ENST00000456790;ENST00000447927;ENST00000566203;ENST00000374450;ENST00000462894;ENST00000435366;ENST00000415116;ENST00000424358;ENST00000635104;ENST00000454184;ENST00000433764;ENST00000374436;ENST00000374443;ENST00000438751;ENST00000453892;ENST00000444717;ENST00000594413;ENST00000456350","GO:0043022(ribosome binding);GO:0042256(mature ribosome assembly);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0003743(translation initiation factor activity);GO:0006412(translation);GO:0006413(translational initiation);GO:0005654(nucleoplasm);GO:0005515(protein binding);GO:0045727(positive regulation of translation);GO:0042254(ribosome biogenesis);GO:0005730(nucleolus);GO:0030687(preribosome, large subunit precursor);GO:0070062(extracellular exosome);GO:0005829(cytosol);GO:0043023(ribosomal large subunit binding);GO:0006110(regulation of glycolytic process);GO:0032868(response to insulin);GO:2000377(regulation of reactive oxygen species metabolic process);GO:0000470(maturation of LSU-rRNA);GO:0000460(maturation of 5.8S rRNA);GO:0000054(ribosomal subunit export from nucleus);GO:0035195(gene silencing by miRNA);GO:0035278(miRNA mediated inhibition of translation);GO:0042304(regulation of fatty acid biosynthetic process);GO:0045652(regulation of megakaryocyte differentiation);GO:1902626(assembly of large subunit precursor of preribosome);GO:0042256(mature ribosome assembly)","03008(Ribosome biogenesis in eukaryotes);03008(Ribosome biogenesis in eukaryotes)","K03264","NA","MMP24 antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:44421];eukaryotic translation initiation factor 6 [Source:HGNC Symbol;Acc:HGNC:6159]",{"v":6.38612408963045,"d":"6.39"},{"v":3.21012547380033,"d":"3.21"},{"v":1.98936899562066,"d":"1.99"},{"v":0.992310897477848,"d":"0.99"},{"v":0.124667870646821,"d":"0.12"},{"v":0.905375009322596,"d":"0.91"},"up","no"]
["MSTRG.8082","NFKBID;AD000864.1","ENST00000590828;ENST00000624076;ENST00000588039;ENST00000641389;ENST00000585925;ENST00000586361;ENST00000590094;ENST00000588497","GO:0005634(nucleus);GO:0005515(protein binding);GO:0006954(inflammatory response);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0003712(transcription cofactor activity);GO:0051059(NF-kappaB binding);GO:0032088(negative regulation of NF-kappaB transcription factor activity);GO:0033085(negative regulation of T cell differentiation in thymus);GO:0043124(negative regulation of I-kappaB kinase/NF-kappaB signaling);GO:0070245(positive regulation of thymocyte apoptotic process);GO:0070245(positive regulation of thymocyte apoptotic process)","NA","NA","NA","NFKB inhibitor delta [Source:HGNC Symbol;Acc:HGNC:15671]",{"v":1.89666716889632,"d":"1.90"},{"v":0.950644688963211,"d":"0.95"},{"v":1.99513781638528,"d":"2.00"},{"v":0.996488405669843,"d":"1.00"},{"v":0.124827858134066,"d":"0.12"},{"v":0.905375009322596,"d":"0.91"},"up","no"]
["ENSG00000166669","ATF7IP2","ENST00000564797;ENST00000396560;ENST00000570163;ENST00000562396;ENST00000396559;ENST00000535850;ENST00000568027;ENST00000566316;ENST00000565616;ENST00000565450;ENST00000562527","GO:0005634(nucleus);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated)","NA","NA","NA","activating transcription factor 7 interacting protein 2 [Source:HGNC Symbol;Acc:HGNC:20397]",{"v":0.962954425754968,"d":"0.96"},{"v":0.476322191049914,"d":"0.48"},{"v":2.02164510461378,"d":"2.02"},{"v":1.01552975750213,"d":"1.02"},{"v":0.124845197680364,"d":"0.12"},{"v":0.905375009322596,"d":"0.91"},"up","no"]
["MSTRG.7178","AC079325.2","ENST00000641710;ENST00000641031","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005515(protein binding);GO:0001816(cytokine production);GO:0030593(neutrophil chemotaxis);GO:0030593(neutrophil chemotaxis)","NA","NA","NA",null,{"v":5.05076157425743,"d":"5.05"},{"v":10.5270772772277,"d":"10.53"},{"v":0.479787641075201,"d":"0.48"},{"v":-1.05953209938432,"d":"-1.06"},{"v":0.124916085340318,"d":"0.12"},{"v":0.905375009322596,"d":"0.91"},"down","no"]
["ENSG00000013392","RWDD2A","ENST00000369724","NA","NA","NA","NA","RWD domain containing 2A [Source:HGNC Symbol;Acc:HGNC:21385]",{"v":0.580881,"d":"0.58"},{"v":0.28219,"d":"0.28"},{"v":2.05847478649137,"d":"2.06"},{"v":1.04157577772081,"d":"1.04"},{"v":0.124939926607335,"d":"0.12"},{"v":0.905375009322596,"d":"0.91"},"up","no"]
["ENSG00000168062","BATF2","ENST00000301887;ENST00000527454","GO:0005634(nucleus);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0005515(protein binding);GO:0030154(cell differentiation);GO:0043011(myeloid dendritic cell differentiation);GO:0042832(defense response to protozoan);GO:0042832(defense response to protozoan)","NA","NA","NA","basic leucine zipper ATF-like transcription factor 2 [Source:HGNC Symbol;Acc:HGNC:25163]",{"v":0.857182422995781,"d":"0.86"},{"v":1.79484837974684,"d":"1.79"},{"v":0.477579294534441,"d":"0.48"},{"v":-1.06618780501834,"d":"-1.07"},{"v":0.125028536640314,"d":"0.13"},{"v":0.905375009322596,"d":"0.91"},"down","no"]
["ENSG00000112137","PHACTR1","ENST00000379335;ENST00000379350;ENST00000379329;ENST00000332995;ENST00000406205;ENST00000489548;ENST00000481706","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0003779(actin binding);GO:0005829(cytosol);GO:0050790(regulation of catalytic activity);GO:0043086(negative regulation of catalytic activity);GO:0030054(cell junction);GO:0045202(synapse);GO:0031532(actin cytoskeleton reorganization);GO:0019888(protein phosphatase regulator activity);GO:0004864(protein phosphatase inhibitor activity);GO:0008157(protein phosphatase 1 binding);GO:0048870(cell motility);GO:0043149(stress fiber assembly);GO:0031032(actomyosin structure organization);GO:0031032(actomyosin structure organization)","NA","NA","NA","phosphatase and actin regulator 1 [Source:HGNC Symbol;Acc:HGNC:20990]",{"v":0.152613800589391,"d":"0.15"},{"v":0.325619891677085,"d":"0.33"},{"v":0.468686970575916,"d":"0.47"},{"v":-1.09330340620824,"d":"-1.09"},{"v":0.125034231306944,"d":"0.13"},{"v":0.905375009322596,"d":"0.91"},"down","no"]
["MSTRG.14366","CHCHD7","ENST00000522166;ENST00000355315;ENST00000518169;ENST00000521982;ENST00000396723;ENST00000523532;ENST00000517636;ENST00000523061;ENST00000522366;ENST00000517933;ENST00000518801;ENST00000523975;ENST00000303759;ENST00000521831;ENST00000518944","GO:0005739(mitochondrion);GO:0005758(mitochondrial intermembrane space);GO:0005758(mitochondrial intermembrane space)","NA","NA","NA","coiled-coil-helix-coiled-coil-helix domain containing 7 [Source:HGNC Symbol;Acc:HGNC:28314]",{"v":1.6551658627685,"d":"1.66"},{"v":0.823733279065803,"d":"0.82"},{"v":2.00934684179037,"d":"2.01"},{"v":1.00672661521183,"d":"1.01"},{"v":0.125244218156513,"d":"0.13"},{"v":0.905375009322596,"d":"0.91"},"up","no"]
["MSTRG.2374","CELF1","MSTRG.2374.3;ENST00000531165;ENST00000539455;ENST00000539254;ENST00000532048;ENST00000358597;ENST00000543178;ENST00000532146;ENST00000395290;ENST00000422993;ENST00000528538;ENST00000534614;ENST00000361904;ENST00000535982;ENST00000530151;ENST00000310513;ENST00000395292;ENST00000524648","GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0006397(mRNA processing);GO:0008380(RNA splicing);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005654(nucleoplasm);GO:0030529(intracellular ribonucleoprotein complex);GO:0005515(protein binding);GO:0043484(regulation of RNA splicing);GO:0009790(embryo development);GO:0006376(mRNA splice site selection);GO:0036002(pre-mRNA binding);GO:0007281(germ cell development);GO:0003729(mRNA binding);GO:0017148(negative regulation of translation);GO:0000900(translation repressor activity, nucleic acid binding);GO:0042835(BRE binding);GO:0016246(RNA interference);GO:0031369(translation initiation factor binding);GO:0007286(spermatid development);GO:0040018(positive regulation of multicellular organism growth);GO:0040018(positive regulation of multicellular organism growth)","NA","NA","NA","CUGBP Elav-like family member 1 [Source:HGNC Symbol;Acc:HGNC:2549]",{"v":2.68243094828244,"d":"2.68"},{"v":5.51438003864504,"d":"5.51"},{"v":0.486442887411429,"d":"0.49"},{"v":-1.0396576647733,"d":"-1.04"},{"v":0.1255017511423,"d":"0.13"},{"v":0.905375009322596,"d":"0.91"},"down","no"]
["MSTRG.8075","TMEM147","ENST00000222284;ENST00000595180;ENST00000596232;ENST00000392204;ENST00000477168;ENST00000599895;ENST00000595467;ENST00000392205","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005515(protein binding);GO:0031648(protein destabilization);GO:0031648(protein destabilization)","NA","NA","NA","transmembrane protein 147 [Source:HGNC Symbol;Acc:HGNC:30414]",{"v":2.75854609886128,"d":"2.76"},{"v":5.7368342489648,"d":"5.74"},{"v":0.480848143618417,"d":"0.48"},{"v":-1.05634674567198,"d":"-1.06"},{"v":0.125692395499665,"d":"0.13"},{"v":0.905375009322596,"d":"0.91"},"down","no"]
["MSTRG.3739","OAS3","ENST00000228928;ENST00000549918;ENST00000546800;ENST00000546973;ENST00000551007;ENST00000548514","GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0016740(transferase activity);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0006955(immune response);GO:0016779(nucleotidyltransferase activity);GO:0005615(extracellular space);GO:0003725(double-stranded RNA binding);GO:0051607(defense response to virus);GO:0002376(immune system process);GO:0045087(innate immune response);GO:0009615(response to virus);GO:0045071(negative regulation of viral genome replication);GO:0006139(nucleobase-containing compound metabolic process);GO:0060333(interferon-gamma-mediated signaling pathway);GO:0060337(type I interferon signaling pathway);GO:0043231(intracellular membrane-bounded organelle);GO:0001730(2'-5'-oligoadenylate synthetase activity);GO:0060700(regulation of ribonuclease activity);GO:0060700(regulation of ribonuclease activity)","04621(NOD-like receptor signaling pathway);05162(Measles);05164(Influenza A);05160(Hepatitis C);05168(Herpes simplex infection);05168(Herpes simplex infection)","K14216","EC:2.7.7.84","2'-5'-oligoadenylate synthetase 3 [Source:HGNC Symbol;Acc:HGNC:8088]",{"v":6.01312601078657,"d":"6.01"},{"v":3.03836375736274,"d":"3.04"},{"v":1.97906718582171,"d":"1.98"},{"v":0.984820590155263,"d":"0.98"},{"v":0.126286487402645,"d":"0.13"},{"v":0.905375009322596,"d":"0.91"},"up","no"]
["MSTRG.11987","GUSBP1","ENST00000508973;ENST00000509649;ENST00000607545;ENST00000449061;ENST00000508260","NA","NA","NA","NA","glucuronidase, beta pseudogene 1 [Source:HGNC Symbol;Acc:HGNC:13670]",{"v":0.500440018536585,"d":"0.50"},{"v":0.245324472357724,"d":"0.25"},{"v":2.03991070979197,"d":"2.04"},{"v":1.02850600447148,"d":"1.03"},{"v":0.126316281753671,"d":"0.13"},{"v":0.905375009322596,"d":"0.91"},"up","no"]
["MSTRG.2269","BTBD10","ENST00000528120;ENST00000278174;ENST00000527102;ENST00000525108;ENST00000526841;ENST00000529708;ENST00000527858;ENST00000525864","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0001650(fibrillar center);GO:0042327(positive regulation of phosphorylation);GO:1901215(negative regulation of neuron death);GO:0044342(type B pancreatic cell proliferation);GO:0044342(type B pancreatic cell proliferation)","NA","NA","NA","BTB domain containing 10 [Source:HGNC Symbol;Acc:HGNC:21445]",{"v":1.95363990472103,"d":"1.95"},{"v":4.03594728497854,"d":"4.04"},{"v":0.484059817131982,"d":"0.48"},{"v":-1.04674275700036,"d":"-1.05"},{"v":0.126508773514118,"d":"0.13"},{"v":0.905375009322596,"d":"0.91"},"down","no"]
["MSTRG.10894","CAMP","ENST00000296435","GO:0005576(extracellular region);GO:0042742(defense response to bacterium);GO:0006952(defense response);GO:0001934(positive regulation of protein phosphorylation);GO:0008284(positive regulation of cell proliferation);GO:0044130(negative regulation of growth of symbiont in host);GO:0044140(negative regulation of growth of symbiont on or near host surface);GO:0045087(innate immune response);GO:0045766(positive regulation of angiogenesis);GO:0050829(defense response to Gram-negative bacterium);GO:0050830(defense response to Gram-positive bacterium);GO:0051873(killing by host of symbiont cells);GO:0061844(antimicrobial humoral immune response mediated by antimicrobial peptide);GO:0071222(cellular response to lipopolysaccharide);GO:0071224(cellular response to peptidoglycan);GO:0071347(cellular response to interleukin-1);GO:0071354(cellular response to interleukin-6);GO:0071356(cellular response to tumor necrosis factor);GO:0005615(extracellular space);GO:0005737(cytoplasm);GO:0042581(specific granule);GO:0042995(cell projection)","04621(NOD-like receptor signaling pathway);04970(Salivary secretion);05152(Tuberculosis)","K13916","NA","cathelicidin antimicrobial peptide [Source:HGNC Symbol;Acc:HGNC:1472]",{"v":7.801955,"d":"7.80"},{"v":16.101738,"d":"16.10"},{"v":0.484541171890885,"d":"0.48"},{"v":-1.04530883696803,"d":"-1.05"},{"v":0.126517302487423,"d":"0.13"},{"v":0.905375009322596,"d":"0.91"},"down","no"]
["MSTRG.2730","CAPN5","ENST00000278559;ENST00000527129;ENST00000527066;ENST00000456580;ENST00000531028","GO:0016787(hydrolase activity);GO:0005622(intracellular);GO:0008233(peptidase activity);GO:0008234(cysteine-type peptidase activity);GO:0006508(proteolysis);GO:0004198(calcium-dependent cysteine-type endopeptidase activity);GO:0005925(focal adhesion);GO:0005737(cytoplasm);GO:0070062(extracellular exosome);GO:0007165(signal transduction);GO:0009986(cell surface);GO:0009986(cell surface)","NA","NA","NA","calpain 5 [Source:HGNC Symbol;Acc:HGNC:1482]",{"v":0.773541108660395,"d":"0.77"},{"v":1.60479515293545,"d":"1.60"},{"v":0.482018597355216,"d":"0.48"},{"v":-1.05283928495795,"d":"-1.05"},{"v":0.126543455413871,"d":"0.13"},{"v":0.905375009322596,"d":"0.91"},"down","no"]
["ENSG00000165309","ARMC3","ENST00000298032;ENST00000464017;ENST00000376528;ENST00000468003;ENST00000447081","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0070062(extracellular exosome);GO:0070062(extracellular exosome)","NA","NA","NA","armadillo repeat containing 3 [Source:HGNC Symbol;Acc:HGNC:30964]",{"v":0.0896114187741106,"d":"0.09"},{"v":0.196056985712245,"d":"0.20"},{"v":0.457068226610575,"d":"0.46"},{"v":-1.12951856232606,"d":"-1.13"},{"v":0.126553722671478,"d":"0.13"},{"v":0.905375009322596,"d":"0.91"},"down","no"]
["ENSG00000137992","DBT","ENST00000370132;ENST00000370131","GO:0016740(transferase activity);GO:0005739(mitochondrion);GO:0016746(transferase activity, transferring acyl groups);GO:0008152(metabolic process);GO:0005759(mitochondrial matrix);GO:0034641(cellular nitrogen compound metabolic process);GO:0042645(mitochondrial nucleoid);GO:0009083(branched-chain amino acid catabolic process);GO:0031625(ubiquitin protein ligase binding);GO:0043754(dihydrolipoyllysine-residue (2-methylpropanoyl)transferase activity);GO:0005947(mitochondrial alpha-ketoglutarate dehydrogenase complex);GO:0005947(mitochondrial alpha-ketoglutarate dehydrogenase complex)","00640(Propanoate metabolism);00280(Valine, leucine and isoleucine degradation);00280(Valine, leucine and isoleucine degradation)","K09699","EC:2.3.1.168","dihydrolipoamide branched chain transacylase E2 [Source:HGNC Symbol;Acc:HGNC:2698]",{"v":0.677141153322127,"d":"0.68"},{"v":0.339706559232062,"d":"0.34"},{"v":1.99331197741035,"d":"1.99"},{"v":0.995167527055453,"d":"1.00"},{"v":0.126572654114976,"d":"0.13"},{"v":0.905375009322596,"d":"0.91"},"up","no"]
["MSTRG.6699","SLFN13","ENST00000533791;ENST00000285013;ENST00000531588;ENST00000524511;ENST00000542635;ENST00000526861;ENST00000532774;ENST00000526483;ENST00000532210","GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0005622(intracellular);GO:0005622(intracellular)","NA","NA","NA","schlafen family member 13 [Source:HGNC Symbol;Acc:HGNC:26481]",{"v":1.58470147271948,"d":"1.58"},{"v":0.796596351055847,"d":"0.80"},{"v":1.98934061224237,"d":"1.99"},{"v":0.9922903136388,"d":"0.99"},{"v":0.126698279850669,"d":"0.13"},{"v":0.905375009322596,"d":"0.91"},"up","no"]
["MSTRG.14908","HSDL2","ENST00000398805;ENST00000480881;ENST00000488101;ENST00000398803;ENST00000467434","GO:0016020(membrane);GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0005777(peroxisome);GO:0003674(molecular_function);GO:0008150(biological_process);GO:0005739(mitochondrion);GO:0005739(mitochondrion)","NA","NA","NA","hydroxysteroid dehydrogenase like 2 [Source:HGNC Symbol;Acc:HGNC:18572]",{"v":4.91477981070912,"d":"4.91"},{"v":10.0951647655572,"d":"10.10"},{"v":0.486844932682765,"d":"0.49"},{"v":-1.03846576913835,"d":"-1.04"},{"v":0.126716533103393,"d":"0.13"},{"v":0.905375009322596,"d":"0.91"},"down","no"]
["MSTRG.15257","INE1","ENST00000456273","NA","NA","NA","NA","inactivation escape 1 (non-protein coding) [Source:HGNC Symbol;Acc:HGNC:6060]",{"v":1.502156,"d":"1.50"},{"v":0.71314,"d":"0.71"},{"v":2.10639706088566,"d":"2.11"},{"v":1.07477741346555,"d":"1.07"},{"v":0.126729339296715,"d":"0.13"},{"v":0.905375009322596,"d":"0.91"},"up","no"]
["MSTRG.12139","POLK","ENST00000241436;ENST00000515295;ENST00000510815;ENST00000508867;ENST00000509126;ENST00000505975;ENST00000507073;ENST00000502567;ENST00000514296;ENST00000506928;ENST00000505069","GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0005654(nucleoplasm);GO:0016740(transferase activity);GO:0003677(DNA binding);GO:0003684(damaged DNA binding);GO:0006281(DNA repair);GO:0006974(cellular response to DNA damage stimulus);GO:0016604(nuclear body);GO:0016779(nucleotidyltransferase activity);GO:0003887(DNA-directed DNA polymerase activity);GO:0006260(DNA replication);GO:0071897(DNA biosynthetic process);GO:0019985(translesion synthesis);GO:0006283(transcription-coupled nucleotide-excision repair);GO:0042276(error-prone translesion synthesis);GO:0006296(nucleotide-excision repair, DNA incision, 5'-to lesion);GO:0033683(nucleotide-excision repair, DNA incision);GO:0006297(nucleotide-excision repair, DNA gap filling);GO:0006297(nucleotide-excision repair, DNA gap filling)","03460(Fanconi anemia pathway);05200(Pathways in cancer);05202(Transcriptional misregulation in cancers);05210(Colorectal cancer);05212(Pancreatic cancer);05225(Hepatocellular carcinoma);05226(Gastric cancer);05214(Glioma);05216(Thyroid cancer);05220(Chronic myeloid leukemia);05217(Basal cell carcinoma);05218(Melanoma);05213(Endometrial cancer);05224(Breast cancer);05222(Small cell lung cancer);05223(Non-small cell lung cancer);05223(Non-small cell lung cancer)","K03511","EC:2.7.7.7","DNA polymerase kappa [Source:HGNC Symbol;Acc:HGNC:9183]",{"v":1.13953343591433,"d":"1.14"},{"v":0.571930796814937,"d":"0.57"},{"v":1.99243237514111,"d":"1.99"},{"v":0.994530758743116,"d":"0.99"},{"v":0.126741590535637,"d":"0.13"},{"v":0.905375009322596,"d":"0.91"},"up","no"]
["MSTRG.8619","CRIM1","ENST00000280527;ENST00000481321","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005576(extracellular region);GO:0004867(serine-type endopeptidase inhibitor activity);GO:0010951(negative regulation of endopeptidase activity);GO:0005886(plasma membrane);GO:0043086(negative regulation of catalytic activity);GO:0005520(insulin-like growth factor binding);GO:0001558(regulation of cell growth);GO:0070062(extracellular exosome);GO:0004857(enzyme inhibitor activity);GO:0007399(nervous system development);GO:0005010(insulin-like growth factor-activated receptor activity);GO:0048009(insulin-like growth factor receptor signaling pathway);GO:0030165(PDZ domain binding);GO:0030165(PDZ domain binding)","NA","NA","NA","cysteine rich transmembrane BMP regulator 1 [Source:HGNC Symbol;Acc:HGNC:2359]",{"v":0.829060462791351,"d":"0.83"},{"v":0.413553065431059,"d":"0.41"},{"v":2.00472571017506,"d":"2.00"},{"v":1.003404858306,"d":"1.00"},{"v":0.126783809665025,"d":"0.13"},{"v":0.905375009322596,"d":"0.91"},"up","no"]
["MSTRG.3663","TXNRD1","ENST00000526691;ENST00000503506;ENST00000529784;ENST00000527335;ENST00000531691;ENST00000528079;ENST00000354940;ENST00000526390;ENST00000527688;ENST00000526950;ENST00000526580;ENST00000525265;ENST00000429002","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005654(nucleoplasm);GO:0016491(oxidoreductase activity);GO:0050660(flavin adenine dinucleotide binding);GO:0055114(oxidation-reduction process);GO:0001650(fibrillar center);GO:0045454(cell redox homeostasis);GO:0005515(protein binding);GO:0016668(oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor);GO:0098869(cellular oxidant detoxification);GO:0009055(electron carrier activity);GO:0015035(protein disulfide oxidoreductase activity);GO:0004791(thioredoxin-disulfide reductase activity);GO:0005739(mitochondrion);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0007165(signal transduction);GO:0015949(nucleobase-containing small molecule interconversion);GO:0034599(cellular response to oxidative stress);GO:0019216(regulation of lipid metabolic process);GO:0001887(selenium compound metabolic process);GO:0098625(methylselenol reductase activity);GO:0098626(methylseleninic acid reductase activity);GO:0000305(response to oxygen radical);GO:0001707(mesoderm formation);GO:0007369(gastrulation);GO:0008283(cell proliferation);GO:0005623(cell);GO:0005623(cell)","00450(Selenocompound metabolism);05200(Pathways in cancer);05225(Hepatocellular carcinoma);05225(Hepatocellular carcinoma)","K22182","EC:1.8.1.9","thioredoxin reductase 1 [Source:HGNC Symbol;Acc:HGNC:12437]",{"v":2.72104095646989,"d":"2.72"},{"v":5.58313438565891,"d":"5.58"},{"v":0.487367985169635,"d":"0.49"},{"v":-1.03691661024791,"d":"-1.04"},{"v":0.126828537124614,"d":"0.13"},{"v":0.905375009322596,"d":"0.91"},"down","no"]
["ENSG00000145375","SPATA5","ENST00000274008","GO:0005737(cytoplasm);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0005739(mitochondrion);GO:0007275(multicellular organism development);GO:0030154(cell differentiation);GO:0007283(spermatogenesis);GO:0007420(brain development)","03008(Ribosome biogenesis in eukaryotes)","K14575","NA","spermatogenesis associated 5 [Source:HGNC Symbol;Acc:HGNC:18119]",{"v":0.731005899842367,"d":"0.73"},{"v":0.365625295986419,"d":"0.37"},{"v":1.99933075710801,"d":"2.00"},{"v":0.999517162510892,"d":"1.00"},{"v":0.126838388766845,"d":"0.13"},{"v":0.905375009322596,"d":"0.91"},"up","no"]
["ENSG00000198853","RUSC2","ENST00000361226;ENST00000455600","GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0031410(cytoplasmic vesicle);GO:0005515(protein binding);GO:0008150(biological_process);GO:0070062(extracellular exosome);GO:0017137(Rab GTPase binding);GO:0017137(Rab GTPase binding)","NA","NA","NA","RUN and SH3 domain containing 2 [Source:HGNC Symbol;Acc:HGNC:23625]",{"v":0.519574663674762,"d":"0.52"},{"v":1.08500839528335,"d":"1.09"},{"v":0.478866952489409,"d":"0.48"},{"v":-1.06230321898094,"d":"-1.06"},{"v":0.126849045532663,"d":"0.13"},{"v":0.905375009322596,"d":"0.91"},"down","no"]
["ENSG00000198169","ZNF251","ENST00000292562;ENST00000530353;ENST00000524394;ENST00000525191","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0005622(intracellular);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding)","NA","NA","NA","zinc finger protein 251 [Source:HGNC Symbol;Acc:HGNC:13045]",{"v":1.22766543915772,"d":"1.23"},{"v":0.613302210164001,"d":"0.61"},{"v":2.00173000979311,"d":"2.00"},{"v":1.00124739884929,"d":"1.00"},{"v":0.126859618328126,"d":"0.13"},{"v":0.905375009322596,"d":"0.91"},"up","no"]
["MSTRG.14853","MFSD14B","ENST00000375344;ENST00000428393","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005215(transporter activity);GO:0055085(transmembrane transport);GO:0055085(transmembrane transport)","NA","NA","NA","major facilitator superfamily domain containing 14B [Source:HGNC Symbol;Acc:HGNC:23376]",{"v":17.8803187491249,"d":"17.88"},{"v":36.6309071271879,"d":"36.63"},{"v":0.488121101861928,"d":"0.49"},{"v":-1.03468897295806,"d":"-1.03"},{"v":0.126873132970778,"d":"0.13"},{"v":0.905375009322596,"d":"0.91"},"down","no"]
["ENSG00000176531","PHLDB3","ENST00000292140;ENST00000601646;ENST00000596141;ENST00000599242;ENST00000594808;ENST00000600660;ENST00000596902","GO:0019899(enzyme binding);GO:0019899(enzyme binding)","NA","NA","NA","pleckstrin homology like domain family B member 3 [Source:HGNC Symbol;Acc:HGNC:30499]",{"v":0.84212425763233,"d":"0.84"},{"v":0.41536700812651,"d":"0.42"},{"v":2.02742211383298,"d":"2.03"},{"v":1.01964649242271,"d":"1.02"},{"v":0.12696482140392,"d":"0.13"},{"v":0.905375009322596,"d":"0.91"},"up","no"]
["MSTRG.4278","AL135999.1","ENST00000555968","NA","NA","NA","NA",null,{"v":1.963509,"d":"1.96"},{"v":0.983487,"d":"0.98"},{"v":1.99647682175768,"d":"2.00"},{"v":0.997456322995578,"d":"1.00"},{"v":0.126980287101595,"d":"0.13"},{"v":0.905375009322596,"d":"0.91"},"up","no"]
["MSTRG.15246","ATP6AP2","ENST00000636580;ENST00000637327;ENST00000637019;ENST00000635774;ENST00000636223;ENST00000637954;ENST00000487051;ENST00000378438;ENST00000423649;ENST00000636639;ENST00000637955;ENST00000637526;ENST00000636409;ENST00000636287;ENST00000635829;ENST00000636196;ENST00000638153;ENST00000637482;ENST00000636251;ENST00000447485;ENST00000638046;ENST00000636574;ENST00000479120;ENST00000637930;ENST00000637793;ENST00000486558;ENST00000636787;ENST00000636970;ENST00000637165","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0004872(receptor activity);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0070062(extracellular exosome);GO:0043312(neutrophil degranulation);GO:0070821(tertiary granule membrane);GO:0101003(ficolin-1-rich granule membrane);GO:0019899(enzyme binding);GO:0002003(angiotensin maturation);GO:0021903(rostrocaudal neural tube patterning);GO:0030177(positive regulation of Wnt signaling pathway);GO:0032914(positive regulation of transforming growth factor beta1 production);GO:0043408(regulation of MAPK cascade);GO:0048069(eye pigmentation);GO:0060323(head morphogenesis);GO:0009897(external side of plasma membrane);GO:0043005(neuron projection);GO:0044297(cell body);GO:0003824(catalytic activity);GO:0008152(metabolic process);GO:0008152(metabolic process)","04614(Renin-angiotensin system);04614(Renin-angiotensin system)","K19514","NA","ATPase H+ transporting accessory protein 2 [Source:HGNC Symbol;Acc:HGNC:18305]",{"v":4.2773351124477,"d":"4.28"},{"v":8.77362000774059,"d":"8.77"},{"v":0.487522266598507,"d":"0.49"},{"v":-1.0364599823274,"d":"-1.04"},{"v":0.127123568675501,"d":"0.13"},{"v":0.905375009322596,"d":"0.91"},"down","no"]
["ENSG00000133111","RFXAP","ENST00000255476","GO:0005634(nucleus);GO:0016607(nuclear speck);GO:0003677(DNA binding);GO:0003713(transcription coactivator activity);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0045893(positive regulation of transcription, DNA-templated)","04612(Antigen processing and presentation);05340(Primary immunodeficiency);05152(Tuberculosis)","K08063","NA","regulatory factor X associated protein [Source:HGNC Symbol;Acc:HGNC:9988]",{"v":0.70794846140503,"d":"0.71"},{"v":0.34590473547268,"d":"0.35"},{"v":2.04665732730607,"d":"2.05"},{"v":1.03326957154533,"d":"1.03"},{"v":0.127153115638294,"d":"0.13"},{"v":0.905375009322596,"d":"0.91"},"up","no"]
["MSTRG.12556","KIAA1191","ENST00000393725;ENST00000298569;ENST00000504688;ENST00000393728;ENST00000506983;ENST00000506668;ENST00000614420;ENST00000508023;ENST00000510164;ENST00000503082;ENST00000620366;ENST00000506613;ENST00000533553","GO:0005737(cytoplasm);GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0005515(protein binding);GO:0003674(molecular_function);GO:0008150(biological_process);GO:0005575(cellular_component);GO:0005575(cellular_component)","NA","NA","NA","KIAA1191 [Source:HGNC Symbol;Acc:HGNC:29209]",{"v":7.19625575157312,"d":"7.20"},{"v":3.63914499798641,"d":"3.64"},{"v":1.97745782472391,"d":"1.98"},{"v":0.983646925185796,"d":"0.98"},{"v":0.127401074411715,"d":"0.13"},{"v":0.905375009322596,"d":"0.91"},"up","no"]
["ENSG00000166341","DCHS1","ENST00000299441","GO:0005622(intracellular);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005509(calcium ion binding);GO:0007155(cell adhesion);GO:0007156(homophilic cell adhesion via plasma membrane adhesion molecules);GO:0005886(plasma membrane);GO:0022008(neurogenesis);GO:0007157(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules);GO:0035329(hippo signaling);GO:0016339(calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules);GO:0001658(branching involved in ureteric bud morphogenesis);GO:0001822(kidney development);GO:0003007(heart morphogenesis);GO:0003183(mitral valve morphogenesis);GO:0003192(mitral valve formation);GO:0003273(cell migration involved in endocardial cushion formation);GO:0007389(pattern specification process);GO:0016477(cell migration);GO:0021915(neural tube development);GO:0036342(post-anal tail morphogenesis);GO:0043931(ossification involved in bone maturation);GO:0048565(digestive tract development);GO:0072006(nephron development);GO:0072137(condensed mesenchymal cell proliferation);GO:0072659(protein localization to plasma membrane);GO:0090102(cochlea development);GO:0098609(cell-cell adhesion);GO:0045177(apical part of cell)","04392(Hippo signaling pathway - multiple species)","K16507","NA","dachsous cadherin-related 1 [Source:HGNC Symbol;Acc:HGNC:13681]",{"v":1.910892,"d":"1.91"},{"v":0.965788,"d":"0.97"},{"v":1.97858329157124,"d":"1.98"},{"v":0.984467799102618,"d":"0.98"},{"v":0.127487129092335,"d":"0.13"},{"v":0.905375009322596,"d":"0.91"},"up","no"]
["ENSG00000138722","MMRN1","ENST00000394980;ENST00000264790;ENST00000506328","GO:0005509(calcium ion binding);GO:0005576(extracellular region);GO:0007596(blood coagulation);GO:0031012(extracellular matrix);GO:0005515(protein binding);GO:0007155(cell adhesion);GO:0002576(platelet degranulation);GO:0031093(platelet alpha granule lumen);GO:0031093(platelet alpha granule lumen)","NA","NA","NA","multimerin 1 [Source:HGNC Symbol;Acc:HGNC:7178]",{"v":0.43130482323049,"d":"0.43"},{"v":0.894813022867514,"d":"0.89"},{"v":0.482005527644571,"d":"0.48"},{"v":-1.05287840349502,"d":"-1.05"},{"v":0.127492165767972,"d":"0.13"},{"v":0.905375009322596,"d":"0.91"},"down","no"]
["ENSG00000140464","PML","ENST00000565898;ENST00000564725;ENST00000268059;ENST00000395132;ENST00000570213;ENST00000563500;ENST00000435786;ENST00000569477;ENST00000268058;ENST00000395135;ENST00000436891;ENST00000564428;ENST00000569965;ENST00000565317;ENST00000354026;ENST00000567606;ENST00000562086;ENST00000566068","GO:0008285(negative regulation of cell proliferation);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0005622(intracellular);GO:0005829(cytosol);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005515(protein binding);GO:0048511(rhythmic process);GO:0006915(apoptotic process);GO:0005654(nucleoplasm);GO:0002376(immune system process);GO:0045087(innate immune response);GO:0005730(nucleolus);GO:0051607(defense response to virus);GO:0005768(endosome);GO:0000784(nuclear chromosome, telomeric region);GO:0001666(response to hypoxia);GO:0016032(viral process);GO:0031625(ubiquitin protein ligase binding);GO:0031901(early endosome membrane);GO:0042803(protein homodimerization activity);GO:0030308(negative regulation of cell growth);GO:0045892(negative regulation of transcription, DNA-templated);GO:1901796(regulation of signal transduction by p53 class mediator);GO:0043161(proteasome-mediated ubiquitin-dependent protein catabolic process);GO:0032922(circadian regulation of gene expression);GO:0016605(PML body);GO:0016525(negative regulation of angiogenesis);GO:0060333(interferon-gamma-mediated signaling pathway);GO:0042406(extrinsic component of endoplasmic reticulum membrane);GO:0006461(protein complex assembly);GO:0001932(regulation of protein phosphorylation);GO:0042752(regulation of circadian rhythm);GO:0090398(cellular senescence);GO:0042771(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator);GO:0043153(entrainment of circadian clock by photoperiod);GO:2001238(positive regulation of extrinsic apoptotic signaling pathway);GO:2000059(negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process);GO:1902187(negative regulation of viral release from host cell);GO:0032206(positive regulation of telomere maintenance);GO:0032183(SUMO binding);GO:0034097(response to cytokine);GO:0032469(endoplasmic reticulum calcium ion homeostasis);GO:0006977(DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest);GO:0010522(regulation of calcium ion transport into cytosol);GO:0030578(PML body organization);GO:0051457(maintenance of protein location in nucleus);GO:2000779(regulation of double-strand break repair);GO:0046332(SMAD binding);GO:0006919(activation of cysteine-type endopeptidase activity involved in apoptotic process);GO:0007050(cell cycle arrest);GO:0007179(transforming growth factor beta receptor signaling pathway);GO:0007182(common-partner SMAD protein phosphorylation);GO:0007184(SMAD protein import into nucleus);GO:0007569(cell aging);GO:0008630(intrinsic apoptotic signaling pathway in response to DNA damage);GO:0008631(intrinsic apoptotic signaling pathway in response to oxidative stress);GO:0009411(response to UV);GO:0010332(response to gamma radiation);GO:0010761(fibroblast migration);GO:0030099(myeloid cell differentiation);GO:0030155(regulation of cell adhesion);GO:0045165(cell fate commitment);GO:0045343(regulation of MHC class I biosynthetic process);GO:0045345(positive regulation of MHC class I biosynthetic process);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0048146(positive regulation of fibroblast proliferation);GO:0048384(retinoic acid receptor signaling pathway);GO:0050711(negative regulation of interleukin-1 secretion);GO:0050713(negative regulation of interleukin-1 beta secretion);GO:0060444(branching involved in mammary gland duct morphogenesis);GO:0070059(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress);GO:0071353(cellular response to interleukin-4);GO:0072332(intrinsic apoptotic signaling pathway by p53 class mediator);GO:0097191(extrinsic apoptotic signaling pathway);GO:1990830(cellular response to leukemia inhibitory factor);GO:2001235(positive regulation of apoptotic signaling pathway);GO:0000792(heterochromatin);GO:0016363(nuclear matrix);GO:0016363(nuclear matrix)","04120(Ubiquitin mediated proteolysis);04144(Endocytosis);05200(Pathways in cancer);05202(Transcriptional misregulation in cancers);05221(Acute myeloid leukemia);05164(Influenza A);05168(Herpes simplex infection);05168(Herpes simplex infection)","K10054","NA","promyelocytic leukemia [Source:HGNC Symbol;Acc:HGNC:9113]",{"v":1.2709486711701,"d":"1.27"},{"v":2.61555395504464,"d":"2.62"},{"v":0.485919500425067,"d":"0.49"},{"v":-1.04121076450661,"d":"-1.04"},{"v":0.127516035169405,"d":"0.13"},{"v":0.905375009322596,"d":"0.91"},"down","no"]
["ENSG00000158050","DUSP2","ENST00000288943;ENST00000488952","GO:0005634(nucleus);GO:0016787(hydrolase activity);GO:0031965(nuclear membrane);GO:0004725(protein tyrosine phosphatase activity);GO:0008138(protein tyrosine/serine/threonine phosphatase activity);GO:0016791(phosphatase activity);GO:0006470(protein dephosphorylation);GO:0016311(dephosphorylation);GO:0035335(peptidyl-tyrosine dephosphorylation);GO:0004721(phosphoprotein phosphatase activity);GO:0017017(MAP kinase tyrosine/serine/threonine phosphatase activity);GO:0005515(protein binding);GO:0001706(endoderm formation);GO:0000188(inactivation of MAPK activity);GO:0008330(protein tyrosine/threonine phosphatase activity);GO:0051019(mitogen-activated protein kinase binding);GO:0051019(mitogen-activated protein kinase binding)","04010(MAPK signaling pathway);04010(MAPK signaling pathway)","K04459","EC:3.1.3.16;EC:3.1.3.48","dual specificity phosphatase 2 [Source:HGNC Symbol;Acc:HGNC:3068]",{"v":4.23975038768116,"d":"4.24"},{"v":2.12667310559006,"d":"2.13"},{"v":1.99360699890208,"d":"1.99"},{"v":0.995381038313836,"d":"1.00"},{"v":0.127547769721942,"d":"0.13"},{"v":0.905375009322596,"d":"0.91"},"up","no"]
["MSTRG.11869","LINC02273","ENST00000499452;ENST00000504144;ENST00000509332","NA","NA","NA","NA","long intergenic non-protein coding RNA 2273 [Source:HGNC Symbol;Acc:HGNC:53188]",{"v":4.07637292292392,"d":"4.08"},{"v":2.04735301243163,"d":"2.05"},{"v":1.99104546122334,"d":"1.99"},{"v":0.993526162260167,"d":"0.99"},{"v":0.127553559410359,"d":"0.13"},{"v":0.905375009322596,"d":"0.91"},"up","no"]
["ENSG00000088035","ALG6","ENST00000371108;ENST00000494765;ENST00000603108;ENST00000465969;ENST00000462390","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016740(transferase activity);GO:0016757(transferase activity, transferring glycosyl groups);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0016758(transferase activity, transferring hexosyl groups);GO:0006486(protein glycosylation);GO:0006490(oligosaccharide-lipid intermediate biosynthetic process);GO:0046527(glucosyltransferase activity);GO:0006488(dolichol-linked oligosaccharide biosynthetic process);GO:0004583(dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity);GO:0042281(dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase activity);GO:0006487(protein N-linked glycosylation);GO:0006487(protein N-linked glycosylation)","00510(N-Glycan biosynthesis);00510(N-Glycan biosynthesis)","K03848","EC:2.4.1.267","ALG6, alpha-1,3-glucosyltransferase [Source:HGNC Symbol;Acc:HGNC:23157]",{"v":0.494827737777778,"d":"0.49"},{"v":1.03196966363636,"d":"1.03"},{"v":0.479498337222578,"d":"0.48"},{"v":-1.06040228253217,"d":"-1.06"},{"v":0.127570791053845,"d":"0.13"},{"v":0.905375009322596,"d":"0.91"},"down","no"]
["MSTRG.34","AL732372.3","ENST00000514436","NA","NA","NA","NA",null,{"v":7.599097,"d":"7.60"},{"v":15.598593,"d":"15.60"},{"v":0.487165541148487,"d":"0.49"},{"v":-1.03751600468983,"d":"-1.04"},{"v":0.127655191597856,"d":"0.13"},{"v":0.905375009322596,"d":"0.91"},"down","no"]
["MSTRG.1356","CD55;AL391597.1","ENST00000367067;ENST00000314754;ENST00000367063;MSTRG.1356.4;ENST00000367064;ENST00000465534;ENST00000343420;ENST00000618707;ENST00000635614;ENST00000391921;ENST00000488171;ENST00000476590","GO:0016020(membrane);GO:0005886(plasma membrane);GO:0005576(extracellular region);GO:0031225(anchored component of membrane);GO:0045121(membrane raft);GO:0002376(immune system process);GO:0045087(innate immune response);GO:0030449(regulation of complement activation);GO:0008289(lipid binding);GO:0046718(viral entry into host cell);GO:0005515(protein binding);GO:0070062(extracellular exosome);GO:0016032(viral process);GO:0005887(integral component of plasma membrane);GO:0043312(neutrophil degranulation);GO:2000563(positive regulation of CD4-positive, alpha-beta T cell proliferation);GO:0006958(complement activation, classical pathway);GO:0009986(cell surface);GO:0030667(secretory granule membrane);GO:0006888(ER to Golgi vesicle-mediated transport);GO:0000139(Golgi membrane);GO:0030133(transport vesicle);GO:0007204(positive regulation of cytosolic calcium ion concentration);GO:0033116(endoplasmic reticulum-Golgi intermediate compartment membrane);GO:0001618(virus receptor activity);GO:0101003(ficolin-1-rich granule membrane);GO:0031664(regulation of lipopolysaccharide-mediated signaling pathway);GO:0035743(CD4-positive, alpha-beta T cell cytokine production);GO:0045730(respiratory burst);GO:0045916(negative regulation of complement activation);GO:2000516(positive regulation of CD4-positive, alpha-beta T cell activation);GO:0043086(negative regulation of catalytic activity);GO:0004857(enzyme inhibitor activity);GO:0007283(spermatogenesis);GO:0043434(response to peptide hormone);GO:0060137(maternal process involved in parturition);GO:0016324(apical plasma membrane);GO:0016324(apical plasma membrane)","04640(Hematopoietic cell lineage);04610(Complement and coagulation cascades);05416(Viral myocarditis);05416(Viral myocarditis)","K04006","NA","CD55 molecule (Cromer blood group) [Source:HGNC Symbol;Acc:HGNC:2665]",{"v":10.5340690588439,"d":"10.53"},{"v":21.5536357450675,"d":"21.55"},{"v":0.488737454016527,"d":"0.49"},{"v":-1.03286842624835,"d":"-1.03"},{"v":0.127695730825927,"d":"0.13"},{"v":0.905375009322596,"d":"0.91"},"down","no"]
["MSTRG.9893","TPD52L2","ENST00000352482;ENST00000348257;ENST00000346249;ENST00000615907;ENST00000474176;ENST00000358548;ENST00000611972;ENST00000369927;ENST00000217121","GO:0003723(RNA binding);GO:0005515(protein binding);GO:0005515(protein binding)","NA","NA","NA","tumor protein D52 like 2 [Source:HGNC Symbol;Acc:HGNC:12007]",{"v":9.44915942181508,"d":"9.45"},{"v":19.3287929584576,"d":"19.33"},{"v":0.488864433600364,"d":"0.49"},{"v":-1.03249364624998,"d":"-1.03"},{"v":0.12779249013778,"d":"0.13"},{"v":0.905375009322596,"d":"0.91"},"down","no"]
["MSTRG.14723","UBE2R2","ENST00000263228","GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0016740(transferase activity);GO:0016567(protein ubiquitination);GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0031625(ubiquitin protein ligase binding);GO:0061630(ubiquitin protein ligase activity);GO:0043161(proteasome-mediated ubiquitin-dependent protein catabolic process);GO:0005829(cytosol);GO:0061631(ubiquitin conjugating enzyme activity);GO:0004842(ubiquitin-protein transferase activity);GO:0070936(protein K48-linked ubiquitination);GO:0006513(protein monoubiquitination)","04120(Ubiquitin mediated proteolysis);05168(Herpes simplex infection)","K02207","EC:2.3.2.23","ubiquitin conjugating enzyme E2 R2 [Source:HGNC Symbol;Acc:HGNC:19907]",{"v":17.644247,"d":"17.64"},{"v":36.076202,"d":"36.08"},{"v":0.489082719960377,"d":"0.49"},{"v":-1.03184960193088,"d":"-1.03"},{"v":0.127853943437589,"d":"0.13"},{"v":0.905375009322596,"d":"0.91"},"down","no"]
["MSTRG.9804","PREX1;AL133342.1","MSTRG.9804.1;MSTRG.9804.4;ENST00000371941;ENST00000482556;ENST00000620554;ENST00000496915;ENST00000618168","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0035556(intracellular signal transduction);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0005089(Rho guanyl-nucleotide exchange factor activity);GO:0035023(regulation of Rho protein signal transduction);GO:0005515(protein binding);GO:0005096(GTPase activator activity);GO:0005085(guanyl-nucleotide exchange factor activity);GO:0007186(G-protein coupled receptor signaling pathway);GO:0051056(regulation of small GTPase mediated signal transduction);GO:0006801(superoxide metabolic process);GO:0006469(negative regulation of protein kinase activity);GO:0030041(actin filament polymerization);GO:0019899(enzyme binding);GO:0005543(phospholipid binding);GO:0043065(positive regulation of apoptotic process);GO:0042119(neutrophil activation);GO:0032007(negative regulation of TOR signaling);GO:0030676(Rac guanyl-nucleotide exchange factor activity);GO:0030217(T cell differentiation);GO:0030335(positive regulation of cell migration);GO:0030593(neutrophil chemotaxis);GO:0030833(regulation of actin filament polymerization);GO:0043547(positive regulation of GTPase activity);GO:0045785(positive regulation of cell adhesion);GO:0050773(regulation of dendrite development);GO:0072593(reactive oxygen species metabolic process);GO:1900026(positive regulation of substrate adhesion-dependent cell spreading);GO:0030426(growth cone);GO:0043198(dendritic shaft);GO:0048471(perinuclear region of cytoplasm);GO:0048471(perinuclear region of cytoplasm)","04062(Chemokine signaling pathway);05167(Kaposi's sarcoma-associated herpesvirus infection);05167(Kaposi's sarcoma-associated herpesvirus infection)","K12365","NA","phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 1 [Source:HGNC Symbol;Acc:HGNC:32594]",{"v":32.7044182063649,"d":"32.70"},{"v":66.8386276498088,"d":"66.84"},{"v":0.489304154742897,"d":"0.49"},{"v":-1.03119656196001,"d":"-1.03"},{"v":0.1278795601078,"d":"0.13"},{"v":0.905375009322596,"d":"0.91"},"down","no"]
["MSTRG.4105","ING1","ENST00000333219;ENST00000338450;ENST00000375774","GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0005515(protein binding);GO:0007049(cell cycle);GO:0008285(negative regulation of cell proliferation);GO:0010941(regulation of cell death);GO:0030308(negative regulation of cell growth);GO:0035064(methylated histone binding);GO:0016569(covalent chromatin modification);GO:0016569(covalent chromatin modification)","NA","NA","NA","inhibitor of growth family member 1 [Source:HGNC Symbol;Acc:HGNC:6062]",{"v":2.82808261756418,"d":"2.83"},{"v":1.42864377097683,"d":"1.43"},{"v":1.97955758812464,"d":"1.98"},{"v":0.985178038013793,"d":"0.99"},{"v":0.127918451115436,"d":"0.13"},{"v":0.905375009322596,"d":"0.91"},"up","no"]
["MSTRG.7188","KCTD2","ENST00000322444;ENST00000579230","GO:0051260(protein homooligomerization);GO:0043161(proteasome-mediated ubiquitin-dependent protein catabolic process);GO:0031463(Cul3-RING ubiquitin ligase complex);GO:0032403(protein complex binding);GO:0097602(cullin family protein binding);GO:0097602(cullin family protein binding)","NA","NA","NA","potassium channel tetramerization domain containing 2 [Source:HGNC Symbol;Acc:HGNC:21294]",{"v":2.0460969085054,"d":"2.05"},{"v":1.03084595377912,"d":"1.03"},{"v":1.984871649352,"d":"1.98"},{"v":0.989045719292557,"d":"0.99"},{"v":0.128027654359003,"d":"0.13"},{"v":0.905375009322596,"d":"0.91"},"up","no"]
["ENSG00000280153","AC133065.6","ENST00000625054","NA","NA","NA","NA",null,{"v":2.869983,"d":"2.87"},{"v":1.438936,"d":"1.44"},{"v":1.9945174768023,"d":"1.99"},{"v":0.996039764982132,"d":"1.00"},{"v":0.12809146624087,"d":"0.13"},{"v":0.905375009322596,"d":"0.91"},"up","no"]
["ENSG00000131127","ZNF141","ENST00000579770;ENST00000505939;ENST00000240499;ENST00000503699;ENST00000512994","GO:0003676(nucleic acid binding);GO:0006355(regulation of transcription, DNA-templated);GO:0005622(intracellular);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0007275(multicellular organism development);GO:0035108(limb morphogenesis);GO:0006366(transcription from RNA polymerase II promoter);GO:0009653(anatomical structure morphogenesis);GO:0009653(anatomical structure morphogenesis)","NA","NA","NA","zinc finger protein 141 [Source:HGNC Symbol;Acc:HGNC:12926]",{"v":0.217597855849582,"d":"0.22"},{"v":0.457813397980501,"d":"0.46"},{"v":0.475298138519856,"d":"0.48"},{"v":-1.07309534347525,"d":"-1.07"},{"v":0.128118890984999,"d":"0.13"},{"v":0.905375009322596,"d":"0.91"},"down","no"]
["MSTRG.1615","THNSL1","ENST00000524413;ENST00000376356","GO:0003674(molecular_function);GO:0008150(biological_process);GO:0005575(cellular_component);GO:0005575(cellular_component)","NA","NA","NA","threonine synthase like 1 [Source:HGNC Symbol;Acc:HGNC:26160]",{"v":0.351601,"d":"0.35"},{"v":0.740779818109821,"d":"0.74"},{"v":0.474636310823299,"d":"0.47"},{"v":-1.07510562048098,"d":"-1.08"},{"v":0.128213452821895,"d":"0.13"},{"v":0.905375009322596,"d":"0.91"},"down","no"]
["MSTRG.8256","BBC3","ENST00000449228;ENST00000601438;ENST00000598636;ENST00000439096;ENST00000341983","GO:0005739(mitochondrion);GO:0006915(apoptotic process);GO:0043065(positive regulation of apoptotic process);GO:0005515(protein binding);GO:0005764(lysosome);GO:0051117(ATPase binding);GO:0090200(positive regulation of release of cytochrome c from mitochondria);GO:0097193(intrinsic apoptotic signaling pathway);GO:0005829(cytosol);GO:0005783(endoplasmic reticulum);GO:0001836(release of cytochrome c from mitochondria);GO:0032464(positive regulation of protein homooligomerization);GO:0042981(regulation of apoptotic process);GO:2001244(positive regulation of intrinsic apoptotic signaling pathway);GO:0005741(mitochondrial outer membrane);GO:0034976(response to endoplasmic reticulum stress);GO:0006919(activation of cysteine-type endopeptidase activity involved in apoptotic process);GO:0070059(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress);GO:2001056(positive regulation of cysteine-type endopeptidase activity);GO:0071456(cellular response to hypoxia);GO:0045926(negative regulation of growth);GO:1900740(positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway);GO:0097194(execution phase of apoptosis);GO:0001844(protein insertion into mitochondrial membrane involved in apoptotic signaling pathway);GO:1902237(positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway);GO:1903896(positive regulation of IRE1-mediated unfolded protein response);GO:0043525(positive regulation of neuron apoptotic process);GO:0051209(release of sequestered calcium ion into cytosol);GO:0006974(cellular response to DNA damage stimulus);GO:0008340(determination of adult lifespan);GO:0070245(positive regulation of thymocyte apoptotic process);GO:0032471(negative regulation of endoplasmic reticulum calcium ion concentration);GO:0032471(negative regulation of endoplasmic reticulum calcium ion concentration)","04390(Hippo signaling pathway);04210(Apoptosis);04215(Apoptosis - multiple species);04115(p53 signaling pathway);05200(Pathways in cancer);05210(Colorectal cancer);05016(Huntington's disease);05162(Measles);01524(Platinum drug resistance);01524(Platinum drug resistance)","K10132","NA","BCL2 binding component 3 [Source:HGNC Symbol;Acc:HGNC:17868]",{"v":1.15568088584906,"d":"1.16"},{"v":2.3935315081761,"d":"2.39"},{"v":0.48283504182057,"d":"0.48"},{"v":-1.05039771120079,"d":"-1.05"},{"v":0.128217160569173,"d":"0.13"},{"v":0.905375009322596,"d":"0.91"},"down","no"]
["MSTRG.10943","GNAI2","MSTRG.10943.8;ENST00000313601;ENST00000491100;ENST00000422163;ENST00000441156;ENST00000440628;ENST00000468422;ENST00000446079;ENST00000490122;ENST00000266027;ENST00000451956;ENST00000492383;ENST00000480090","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005525(GTP binding);GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0007186(G-protein coupled receptor signaling pathway);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0007165(signal transduction);GO:0003924(GTPase activity);GO:0004871(signal transducer activity);GO:0051301(cell division);GO:0005886(plasma membrane);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0007049(cell cycle);GO:0019001(guanyl nucleotide binding);GO:0031683(G-protein beta/gamma-subunit complex binding);GO:0007188(adenylate cyclase-modulating G-protein coupled receptor signaling pathway);GO:0005813(centrosome);GO:0005815(microtubule organizing center);GO:0030496(midbody);GO:0070062(extracellular exosome);GO:0001664(G-protein coupled receptor binding);GO:0006457(protein folding);GO:0007193(adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway);GO:0005834(heterotrimeric G-protein complex);GO:1903561(extracellular vesicle);GO:0007584(response to nutrient);GO:0007194(negative regulation of adenylate cyclase activity);GO:0001973(adenosine receptor signaling pathway);GO:0007214(gamma-aminobutyric acid signaling pathway);GO:0000186(activation of MAPKK activity);GO:0007213(G-protein coupled acetylcholine receptor signaling pathway);GO:0008283(cell proliferation);GO:0008284(positive regulation of cell proliferation);GO:0035556(intracellular signal transduction);GO:0050805(negative regulation of synaptic transmission);GO:0051924(regulation of calcium ion transport);GO:0005634(nucleus);GO:0030425(dendrite);GO:0044297(cell body);GO:0045121(membrane raft);GO:0045121(membrane raft)","04015(Rap1 signaling pathway);04371(Apelin signaling pathway);04071(Sphingolipid signaling pathway);04024(cAMP signaling pathway);04022(cGMP - PKG signaling pathway);04540(Gap junction);04611(Platelet activation);04670(Leukocyte transendothelial migration);04062(Chemokine signaling pathway);04923(Regulation of lipolysis in adipocyte);04915(Estrogen signaling pathway);04914(Progesterone-mediated oocyte maturation);04921(Oxytocin signaling pathway);04926(Relaxin signaling pathway);04916(Melanogenesis);04924(Renin secretion);04261(Adrenergic signaling in cardiomyocytes);04971(Gastric acid secretion);04724(Glutamatergic synapse);04727(GABAergic synapse);04725(Cholinergic synapse);04728(Dopaminergic synapse);04726(Serotonergic synapse);04730(Long-term depression);04723(Retrograde endocannabinoid signaling);04360(Axon guidance);04713(Circadian entrainment);05200(Pathways in cancer);05012(Parkinson's disease);05030(Cocaine addiction);05032(Morphine addiction);05034(Alcoholism);05133(Pertussis);05145(Toxoplasmosis);05142(Chagas disease (American trypanosomiasis));05142(Chagas disease (American trypanosomiasis))","K04630","NA","G protein subunit alpha i2 [Source:HGNC Symbol;Acc:HGNC:4385]",{"v":32.7515275062151,"d":"32.75"},{"v":66.8916912214612,"d":"66.89"},{"v":0.489620263864808,"d":"0.49"},{"v":-1.03026482694606,"d":"-1.03"},{"v":0.128265218892572,"d":"0.13"},{"v":0.905375009322596,"d":"0.91"},"down","no"]
["MSTRG.3044","FOXM1","ENST00000627656;ENST00000536066;ENST00000366362;ENST00000535350;ENST00000545049;ENST00000342628;ENST00000361953;ENST00000538564","GO:0008284(positive regulation of cell proliferation);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:2000377(regulation of reactive oxygen species metabolic process);GO:0005634(nucleus);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0043565(sequence-specific DNA binding);GO:0005515(protein binding);GO:0006281(DNA repair);GO:0006974(cellular response to DNA damage stimulus);GO:0007049(cell cycle);GO:0045893(positive regulation of transcription, DNA-templated);GO:0005654(nucleoplasm);GO:0019901(protein kinase binding);GO:0000981(RNA polymerase II transcription factor activity, sequence-specific DNA binding);GO:0000086(G2/M transition of mitotic cell cycle);GO:0009653(anatomical structure morphogenesis);GO:0030154(cell differentiation);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0045892(negative regulation of transcription, DNA-templated);GO:0000977(RNA polymerase II regulatory region sequence-specific DNA binding);GO:0001227(transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding);GO:0051726(regulation of cell cycle);GO:0032873(negative regulation of stress-activated MAPK cascade);GO:0006978(DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator);GO:0046578(regulation of Ras protein signal transduction);GO:0071156(regulation of cell cycle arrest);GO:0090344(negative regulation of cell aging);GO:2000781(positive regulation of double-strand break repair);GO:2000781(positive regulation of double-strand break repair)","04218(Cellular senescence);04218(Cellular senescence)","K09406","NA","forkhead box M1 [Source:HGNC Symbol;Acc:HGNC:3818]",{"v":0.671991239028373,"d":"0.67"},{"v":0.330934883241478,"d":"0.33"},{"v":2.03058448370954,"d":"2.03"},{"v":1.02189505272061,"d":"1.02"},{"v":0.128451764719826,"d":"0.13"},{"v":0.905568420997846,"d":"0.91"},"up","no"]
["MSTRG.7968","SLC27A1","ENST00000252595;ENST00000599380;ENST00000600297;ENST00000598424;ENST00000594962;ENST00000599965;ENST00000593701;ENST00000598848;ENST00000600277","GO:0016021(integral component of membrane);GO:0003824(catalytic activity);GO:0008152(metabolic process);GO:0001676(long-chain fatty acid metabolic process);GO:0004467(long-chain fatty acid-CoA ligase activity);GO:0031957(very long-chain fatty acid-CoA ligase activity);GO:0015245(fatty acid transporter activity);GO:0015908(fatty acid transport);GO:0006810(transport);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0000166(nucleotide binding);GO:0006629(lipid metabolic process);GO:0006631(fatty acid metabolic process);GO:0005886(plasma membrane);GO:0016874(ligase activity);GO:0006646(phosphatidylethanolamine biosynthetic process);GO:0006869(lipid transport);GO:0012505(endomembrane system);GO:0006656(phosphatidylcholine biosynthetic process);GO:0006661(phosphatidylinositol biosynthetic process);GO:0006659(phosphatidylserine biosynthetic process);GO:0019216(regulation of lipid metabolic process);GO:0032049(cardiolipin biosynthetic process);GO:0015909(long-chain fatty acid transport);GO:0006655(phosphatidylglycerol biosynthetic process);GO:0042803(protein homodimerization activity);GO:0001579(medium-chain fatty acid transport);GO:0006654(phosphatidic acid biosynthetic process);GO:0009409(response to cold);GO:0031652(positive regulation of heat generation);GO:0032868(response to insulin);GO:0033211(adiponectin-activated signaling pathway);GO:0071072(negative regulation of phospholipid biosynthetic process);GO:0071902(positive regulation of protein serine/threonine kinase activity);GO:0005783(endoplasmic reticulum);GO:0005783(endoplasmic reticulum)","03320(PPAR signaling pathway);04931(Insulin resistance);04931(Insulin resistance)","K08745","EC:6.2.1.-","solute carrier family 27 member 1 [Source:HGNC Symbol;Acc:HGNC:10995]",{"v":0.935252016850527,"d":"0.94"},{"v":1.92906125578858,"d":"1.93"},{"v":0.484822352864169,"d":"0.48"},{"v":-1.0444718787026,"d":"-1.04"},{"v":0.128493287534576,"d":"0.13"},{"v":0.905568420997846,"d":"0.91"},"down","no"]
["ENSG00000064651","SLC12A2","ENST00000262461;ENST00000504416;ENST00000509205;ENST00000502849;ENST00000509616;ENST00000507791","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005215(transporter activity);GO:0055085(transmembrane transport);GO:0006811(ion transport);GO:0015293(symporter activity);GO:0006813(potassium ion transport);GO:0005515(protein binding);GO:0006814(sodium ion transport);GO:1902476(chloride transmembrane transport);GO:0015377(cation:chloride symporter activity);GO:0005886(plasma membrane);GO:0072488(ammonium transmembrane transport);GO:0070062(extracellular exosome);GO:0005887(integral component of plasma membrane);GO:0016324(apical plasma membrane);GO:1903561(extracellular vesicle);GO:0019901(protein kinase binding);GO:0008519(ammonium transmembrane transporter activity);GO:0015696(ammonium transport);GO:0008511(sodium:potassium:chloride symporter activity);GO:0006821(chloride transport);GO:0006972(hyperosmotic response);GO:0007214(gamma-aminobutyric acid signaling pathway);GO:0007568(aging);GO:0030321(transepithelial chloride transport);GO:0045795(positive regulation of cell volume);GO:0070634(transepithelial ammonium transport);GO:0070634(transepithelial ammonium transport)","04970(Salivary secretion);04972(Pancreatic secretion);05110(Vibrio cholerae infection);05110(Vibrio cholerae infection)","K10951","NA","solute carrier family 12 member 2 [Source:HGNC Symbol;Acc:HGNC:10911]",{"v":0.367123828300825,"d":"0.37"},{"v":0.182817336646662,"d":"0.18"},{"v":2.00814558966242,"d":"2.01"},{"v":1.00586386782944,"d":"1.01"},{"v":0.128629697648332,"d":"0.13"},{"v":0.905568420997846,"d":"0.91"},"up","no"]
["MSTRG.5535","RNPS1","MSTRG.5535.13;ENST00000566458;ENST00000397086;ENST00000320225;ENST00000568631;ENST00000565243;ENST00000564822;ENST00000569709;ENST00000570051;ENST00000567147;ENST00000565678;ENST00000566397;ENST00000561518;ENST00000565589;ENST00000563857;ENST00000566783;ENST00000565870;ENST00000562205;ENST00000564601;ENST00000569598;ENST00000564764;ENST00000561718","GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0006397(mRNA processing);GO:0008380(RNA splicing);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016607(nuclear speck);GO:0005654(nucleoplasm);GO:0005515(protein binding);GO:0005829(cytosol);GO:0043065(positive regulation of apoptotic process);GO:0006369(termination of RNA polymerase II transcription);GO:0006405(RNA export from nucleus);GO:0031124(mRNA 3'-end processing);GO:0035145(exon-exon junction complex);GO:0000381(regulation of alternative mRNA splicing, via spliceosome);GO:0048025(negative regulation of mRNA splicing, via spliceosome);GO:0061574(ASAP complex);GO:0003730(mRNA 3'-UTR binding);GO:0000398(mRNA splicing, via spliceosome);GO:0000184(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay);GO:0006406(mRNA export from nucleus);GO:0006351(transcription, DNA-templated);GO:0006351(transcription, DNA-templated)","03013(RNA transport);03015(mRNA surveillance pathway);03015(mRNA surveillance pathway)","K14325","NA","RNA binding protein with serine rich domain 1 [Source:HGNC Symbol;Acc:HGNC:10080]",{"v":5.44630600477744,"d":"5.45"},{"v":2.75699393031927,"d":"2.76"},{"v":1.97545085061059,"d":"1.98"},{"v":0.982181952383694,"d":"0.98"},{"v":0.128643398157136,"d":"0.13"},{"v":0.905568420997846,"d":"0.91"},"up","no"]
["ENSG00000179222","MAGED1","ENST00000375722;ENST00000326587;ENST00000375772;ENST00000470461;ENST00000482188;ENST00000482599;ENST00000473931;ENST00000375695;ENST00000494718","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0006355(regulation of transcription, DNA-templated);GO:0042981(regulation of apoptotic process);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0048511(rhythmic process);GO:0042802(identical protein binding);GO:0032922(circadian regulation of gene expression);GO:0043234(protein complex);GO:0000785(chromatin);GO:0050680(negative regulation of epithelial cell proliferation);GO:0003713(transcription coactivator activity);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0042752(regulation of circadian rhythm);GO:0043406(positive regulation of MAP kinase activity);GO:0045892(negative regulation of transcription, DNA-templated);GO:0045893(positive regulation of transcription, DNA-templated);GO:0090190(positive regulation of branching involved in ureteric bud morphogenesis);GO:2001235(positive regulation of apoptotic signaling pathway);GO:2001235(positive regulation of apoptotic signaling pathway)","04722(Neurotrophin signaling pathway);04722(Neurotrophin signaling pathway)","K12464","NA","MAGE family member D1 [Source:HGNC Symbol;Acc:HGNC:6813]",{"v":3.38757287583112,"d":"3.39"},{"v":1.70997234358378,"d":"1.71"},{"v":1.98106880999689,"d":"1.98"},{"v":0.986278991341594,"d":"0.99"},{"v":0.128736048398006,"d":"0.13"},{"v":0.905568420997846,"d":"0.91"},"up","no"]
["MSTRG.11116","ATP6V1A","ENST00000273398;ENST00000475322;ENST00000470455;ENST00000461496;ENST00000462855","GO:0006810(transport);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0016787(hydrolase activity);GO:0005765(lysosomal membrane);GO:0005829(cytosol);GO:0015992(proton transport);GO:0006811(ion transport);GO:0005886(plasma membrane);GO:0006879(cellular iron ion homeostasis);GO:0015991(ATP hydrolysis coupled proton transport);GO:0046961(proton-transporting ATPase activity, rotational mechanism);GO:0033180(proton-transporting V-type ATPase, V1 domain);GO:0046034(ATP metabolic process);GO:0070062(extracellular exosome);GO:0034220(ion transmembrane transport);GO:0005887(integral component of plasma membrane);GO:0008286(insulin receptor signaling pathway);GO:0016241(regulation of macroautophagy);GO:0033572(transferrin transport);GO:0090383(phagosome acidification);GO:0036295(cellular response to increased oxygen levels);GO:0016469(proton-transporting two-sector ATPase complex);GO:0005739(mitochondrion);GO:0005902(microvillus);GO:0016324(apical plasma membrane);GO:0043209(myelin sheath);GO:0043209(myelin sheath)","00190(Oxidative phosphorylation);04150(mTOR signaling pathway);04145(Phagosome);04966(Collecting duct acid secretion);04721(Synaptic vesicle cycle);05323(Rheumatoid arthritis);05110(Vibrio cholerae infection);05120(Epithelial cell signaling in Helicobacter pylori infection);05120(Epithelial cell signaling in Helicobacter pylori infection)","K02145","EC:3.6.3.14","ATPase H+ transporting V1 subunit A [Source:HGNC Symbol;Acc:HGNC:851]",{"v":6.88596899922027,"d":"6.89"},{"v":14.0627675812866,"d":"14.06"},{"v":0.489659589367278,"d":"0.49"},{"v":-1.03014895668234,"d":"-1.03"},{"v":0.128743824675993,"d":"0.13"},{"v":0.905568420997846,"d":"0.91"},"down","no"]
["ENSG00000241015","TPM3P9","ENST00000424846","NA","NA","NA","NA","tropomyosin 3 pseudogene 9 [Source:HGNC Symbol;Acc:HGNC:44142]",{"v":1.832816,"d":"1.83"},{"v":0.921046,"d":"0.92"},{"v":1.98992884177337,"d":"1.99"},{"v":0.992716842097487,"d":"0.99"},{"v":0.128886034477725,"d":"0.13"},{"v":0.905696714853307,"d":"0.91"},"up","no"]
["ENSG00000166436","TRIM66","ENST00000299550;ENST00000481014;ENST00000531498;ENST00000402157;ENST00000525788;ENST00000529057;ENST00000529211;ENST00000530502","GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0005654(nucleoplasm);GO:0005622(intracellular);GO:0016235(aggresome);GO:0005634(nucleus);GO:0005634(nucleus)","NA","NA","NA","tripartite motif containing 66 [Source:HGNC Symbol;Acc:HGNC:29005]",{"v":0.252364296690089,"d":"0.25"},{"v":0.523715400887574,"d":"0.52"},{"v":0.481872971966055,"d":"0.48"},{"v":-1.05327521164319,"d":"-1.05"},{"v":0.128912487066813,"d":"0.13"},{"v":0.905696714853307,"d":"0.91"},"down","no"]
["MSTRG.1908","BLOC1S2","ENST00000370372;ENST00000614731;ENST00000441611;ENST00000361832;ENST00000618916;ENST00000579542","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005765(lysosomal membrane);GO:1904115(axon cytoplasm);GO:0005739(mitochondrion);GO:0055114(oxidation-reduction process);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0005764(lysosome);GO:0005815(microtubule organizing center);GO:0016491(oxidoreductase activity);GO:0008089(anterograde axonal transport);GO:0032438(melanosome organization);GO:0048490(anterograde synaptic vesicle transport);GO:0008625(extrinsic apoptotic signaling pathway via death domain receptors);GO:0031175(neuron projection development);GO:0043015(gamma-tubulin binding);GO:0032418(lysosome localization);GO:0031083(BLOC-1 complex);GO:0099078(BORC complex);GO:0000930(gamma-tubulin complex);GO:0060155(platelet dense granule organization);GO:0097345(mitochondrial outer membrane permeabilization);GO:0005829(cytosol);GO:0005829(cytosol)","NA","NA","NA","biogenesis of lysosomal organelles complex 1 subunit 2 [Source:HGNC Symbol;Acc:HGNC:20984]",{"v":1.27084816717635,"d":"1.27"},{"v":2.63573956201155,"d":"2.64"},{"v":0.48215999239563,"d":"0.48"},{"v":-1.05241614773578,"d":"-1.05"},{"v":0.129086925403086,"d":"0.13"},{"v":0.906186768860151,"d":"0.91"},"down","no"]
["ENSG00000135953","MFSD9","ENST00000258436;ENST00000428085;ENST00000421966;ENST00000462099;ENST00000438943;ENST00000496253;ENST00000411991","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005215(transporter activity);GO:0055085(transmembrane transport);GO:0055085(transmembrane transport)","NA","NA","NA","major facilitator superfamily domain containing 9 [Source:HGNC Symbol;Acc:HGNC:28158]",{"v":0.958326414701168,"d":"0.96"},{"v":1.97014977810854,"d":"1.97"},{"v":0.486423126479865,"d":"0.49"},{"v":-1.03971627304529,"d":"-1.04"},{"v":0.129132743345293,"d":"0.13"},{"v":0.906186768860151,"d":"0.91"},"down","no"]
["MSTRG.14703","HACD4","MSTRG.14703.2;ENST00000495827;ENST00000488436","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016829(lyase activity);GO:0006629(lipid metabolic process);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0006631(fatty acid metabolic process);GO:0006633(fatty acid biosynthetic process);GO:0042761(very long-chain fatty acid biosynthetic process);GO:0030148(sphingolipid biosynthetic process);GO:0030176(integral component of endoplasmic reticulum membrane);GO:0102343(3-hydroxy-arachidoyl-CoA dehydratase activity);GO:0102344(3-hydroxy-behenoyl-CoA dehydratase activity);GO:0102345(3-hydroxy-lignoceroyl-CoA dehydratase activity);GO:0019899(enzyme binding);GO:0018812(3-hydroxyacyl-CoA dehydratase activity);GO:0030497(fatty acid elongation);GO:0030497(fatty acid elongation)","00062(Fatty acid elongation);01040(Biosynthesis of unsaturated fatty acids);01040(Biosynthesis of unsaturated fatty acids)","K10703","EC:4.2.1.134","3-hydroxyacyl-CoA dehydratase 4 [Source:HGNC Symbol;Acc:HGNC:20920]",{"v":2.94485717338753,"d":"2.94"},{"v":6.01355511519949,"d":"6.01"},{"v":0.489703198353382,"d":"0.49"},{"v":-1.03002047626871,"d":"-1.03"},{"v":0.129213031117237,"d":"0.13"},{"v":0.906222085447741,"d":"0.91"},"down","no"]
["MSTRG.7229","ACOX1","ENST00000293217;ENST00000588968;ENST00000592329;ENST00000301608;ENST00000576743;ENST00000589301;ENST00000587927;ENST00000572047;ENST00000589744;ENST00000591857;ENST00000573078","GO:0016020(membrane);GO:0043231(intracellular membrane-bounded organelle);GO:0005634(nucleus);GO:0005730(nucleolus);GO:0005654(nucleoplasm);GO:0016491(oxidoreductase activity);GO:0050660(flavin adenine dinucleotide binding);GO:0055114(oxidation-reduction process);GO:0016627(oxidoreductase activity, acting on the CH-CH group of donors);GO:0006629(lipid metabolic process);GO:0008152(metabolic process);GO:0005886(plasma membrane);GO:0006631(fatty acid metabolic process);GO:0071949(FAD binding);GO:0005777(peroxisome);GO:0003997(acyl-CoA oxidase activity);GO:0006635(fatty acid beta-oxidation);GO:0005102(receptor binding);GO:0005782(peroxisomal matrix);GO:0047485(protein N-terminus binding);GO:0006693(prostaglandin metabolic process);GO:0033540(fatty acid beta-oxidation using acyl-CoA oxidase);GO:0036109(alpha-linolenic acid metabolic process);GO:0003995(acyl-CoA dehydrogenase activity);GO:0033539(fatty acid beta-oxidation using acyl-CoA dehydrogenase);GO:0019216(regulation of lipid metabolic process);GO:0006091(generation of precursor metabolites and energy);GO:0019395(fatty acid oxidation);GO:0030165(PDZ domain binding);GO:0000038(very long-chain fatty acid metabolic process);GO:0007283(spermatogenesis);GO:0005737(cytoplasm);GO:0005739(mitochondrion);GO:0005778(peroxisomal membrane);GO:0005778(peroxisomal membrane)","00071(Fatty acid degradation);00592(alpha-Linolenic acid metabolism);01040(Biosynthesis of unsaturated fatty acids);04024(cAMP signaling pathway);04146(Peroxisome);03320(PPAR signaling pathway);03320(PPAR signaling pathway)","K00232","EC:1.3.3.6","acyl-CoA oxidase 1 [Source:HGNC Symbol;Acc:HGNC:119]",{"v":3.87712933274315,"d":"3.88"},{"v":7.91162782152974,"d":"7.91"},{"v":0.490054565280789,"d":"0.49"},{"v":-1.02898569937947,"d":"-1.03"},{"v":0.129482949978362,"d":"0.13"},{"v":0.90758654460968,"d":"0.91"},"down","no"]
["ENSG00000115339","GALNT3","ENST00000392701;ENST00000431484;ENST00000463254;ENST00000412248;ENST00000437849;ENST00000422973","GO:0048471(perinuclear region of cytoplasm);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005794(Golgi apparatus);GO:0046872(metal ion binding);GO:0016740(transferase activity);GO:0030246(carbohydrate binding);GO:0016757(transferase activity, transferring glycosyl groups);GO:0006486(protein glycosylation);GO:0032580(Golgi cisterna membrane);GO:0070062(extracellular exosome);GO:0005975(carbohydrate metabolic process);GO:0000139(Golgi membrane);GO:0005509(calcium ion binding);GO:0008543(fibroblast growth factor receptor signaling pathway);GO:0016266(O-glycan processing);GO:0030145(manganese ion binding);GO:0004653(polypeptide N-acetylgalactosaminyltransferase activity);GO:0018242(protein O-linked glycosylation via serine);GO:0018243(protein O-linked glycosylation via threonine);GO:0018243(protein O-linked glycosylation via threonine)","00512(Mucin type O-glycan biosynthesis);00512(Mucin type O-glycan biosynthesis)","K00710","EC:2.4.1.41","polypeptide N-acetylgalactosaminyltransferase 3 [Source:HGNC Symbol;Acc:HGNC:4125]",{"v":1.5604532240717,"d":"1.56"},{"v":3.19717670849338,"d":"3.20"},{"v":0.488072248220224,"d":"0.49"},{"v":-1.03483337243931,"d":"-1.03"},{"v":0.129746360078801,"d":"0.13"},{"v":0.908903820866155,"d":"0.91"},"down","no"]
["ENSG00000115947","ORC4","ENST00000483608;ENST00000535373;ENST00000481488;ENST00000478904;ENST00000488761;ENST00000490200;ENST00000416719;ENST00000392857;ENST00000495601;ENST00000440042;ENST00000540442;ENST00000264169","GO:0005634(nucleus);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0005730(nucleolus);GO:0005829(cytosol);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0006260(DNA replication);GO:0000808(origin recognition complex);GO:0005654(nucleoplasm);GO:0000784(nuclear chromosome, telomeric region);GO:0000082(G1/S transition of mitotic cell cycle);GO:0005664(nuclear origin of replication recognition complex);GO:0003688(DNA replication origin binding);GO:0006270(DNA replication initiation);GO:0006270(DNA replication initiation)","04110(Cell cycle);04110(Cell cycle)","K02606","NA","origin recognition complex subunit 4 [Source:HGNC Symbol;Acc:HGNC:8490]",{"v":0.544156205720695,"d":"0.54"},{"v":1.12166992181716,"d":"1.12"},{"v":0.485130424857195,"d":"0.49"},{"v":-1.04355543418751,"d":"-1.04"},{"v":0.129847016407014,"d":"0.13"},{"v":0.909080099751898,"d":"0.91"},"down","no"]
["ENSG00000141577","CEP131","ENST00000269392;ENST00000573053;ENST00000570817;ENST00000571292;ENST00000450824","GO:0006810(transport);GO:0005737(cytoplasm);GO:0043231(intracellular membrane-bounded organelle);GO:0045171(intercellular bridge);GO:0042803(protein homodimerization activity);GO:0015630(microtubule cytoskeleton);GO:0005856(cytoskeleton);GO:0042995(cell projection);GO:0005515(protein binding);GO:0007049(cell cycle);GO:0007275(multicellular organism development);GO:0005815(microtubule organizing center);GO:0030154(cell differentiation);GO:0031410(cytoplasmic vesicle);GO:0007283(spermatogenesis);GO:0005813(centrosome);GO:0003674(molecular_function);GO:0005829(cytosol);GO:0030030(cell projection organization);GO:0001669(acrosomal vesicle);GO:0000086(G2/M transition of mitotic cell cycle);GO:0010389(regulation of G2/M transition of mitotic cell cycle);GO:0097711(ciliary basal body docking);GO:0008284(positive regulation of cell proliferation);GO:0035869(ciliary transition zone);GO:0035735(intraciliary transport involved in cilium assembly);GO:0032403(protein complex binding);GO:0090316(positive regulation of intracellular protein transport);GO:0034451(centriolar satellite);GO:0010824(regulation of centrosome duplication);GO:0071539(protein localization to centrosome);GO:0005929(cilium);GO:0005929(cilium)","NA","NA","NA","centrosomal protein 131 [Source:HGNC Symbol;Acc:HGNC:29511]",{"v":1.40356594326778,"d":"1.40"},{"v":0.706771913262733,"d":"0.71"},{"v":1.98588245646092,"d":"1.99"},{"v":0.989780232886685,"d":"0.99"},{"v":0.130067048525415,"d":"0.13"},{"v":0.909185561805303,"d":"0.91"},"up","no"]
["MSTRG.4453","L3HYPDH;CCDC175;GPR135","ENST00000481608;ENST00000543619;ENST00000247194;ENST00000527981;ENST00000537690;ENST00000478430;ENST00000395116;ENST00000481661;ENST00000463432;ENST00000487285","GO:0016829(lyase activity);GO:0008152(metabolic process);GO:0016836(hydro-lyase activity);GO:0050346(trans-L-3-hydroxyproline dehydratase activity);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0004930(G-protein coupled receptor activity);GO:0007186(G-protein coupled receptor signaling pathway);GO:0005886(plasma membrane);GO:0004871(signal transducer activity);GO:0007165(signal transduction);GO:0050346(trans-L-3-hydroxyproline dehydratase activity)","00330(Arginine and proline metabolism);00330(Arginine and proline metabolism)","K18384","EC:4.2.1.77","trans-L-3-hydroxyproline dehydratase [Source:HGNC Symbol;Acc:HGNC:20488];coiled-coil domain containing 175 [Source:HGNC Symbol;Acc:HGNC:19847];G protein-coupled receptor 135 [Source:HGNC Symbol;Acc:HGNC:19991]",{"v":0.450176909950551,"d":"0.45"},{"v":0.226291111477401,"d":"0.23"},{"v":1.98937071372999,"d":"1.99"},{"v":0.992312143454213,"d":"0.99"},{"v":0.130098060338137,"d":"0.13"},{"v":0.909185561805303,"d":"0.91"},"up","no"]
["MSTRG.7832","ELOF1","ENST00000252445;ENST00000586683;ENST00000590700;ENST00000587806;ENST00000593077;ENST00000591674;ENST00000586120;ENST00000591912;ENST00000589171","GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003746(translation elongation factor activity);GO:0006414(translational elongation);GO:0005515(protein binding);GO:0006368(transcription elongation from RNA polymerase II promoter);GO:0000993(RNA polymerase II core binding);GO:0048096(chromatin-mediated maintenance of transcription);GO:0008023(transcription elongation factor complex);GO:0008023(transcription elongation factor complex)","NA","NA","NA","elongation factor 1 homolog [Source:HGNC Symbol;Acc:HGNC:28691]",{"v":1.84580209369758,"d":"1.85"},{"v":3.77818039012701,"d":"3.78"},{"v":0.488542605991222,"d":"0.49"},{"v":-1.03344370920983,"d":"-1.03"},{"v":0.13015390979829,"d":"0.13"},{"v":0.909185561805303,"d":"0.91"},"down","no"]
["MSTRG.1097","FCRL3","ENST00000368184;ENST00000477837;ENST00000468507;ENST00000473231;ENST00000485028;ENST00000480682;ENST00000457799;ENST00000492769;ENST00000494724;ENST00000496769;ENST00000478179","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005886(plasma membrane);GO:0005886(plasma membrane)","NA","NA","NA","Fc receptor like 3 [Source:HGNC Symbol;Acc:HGNC:18506]",{"v":4.67571473891098,"d":"4.68"},{"v":2.37995694921994,"d":"2.38"},{"v":1.96462156193351,"d":"1.96"},{"v":0.974251438029613,"d":"0.97"},{"v":0.130164084749406,"d":"0.13"},{"v":0.909185561805303,"d":"0.91"},"up","no"]
["MSTRG.5823","YPEL3","ENST00000398841;ENST00000568674;ENST00000570099;ENST00000568681;ENST00000565479;ENST00000562641;ENST00000398838;ENST00000563788;ENST00000566401;ENST00000565110;ENST00000566134;ENST00000566595","GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0005730(nucleolus);GO:2000774(positive regulation of cellular senescence);GO:2000774(positive regulation of cellular senescence)","NA","NA","NA","yippee like 3 [Source:HGNC Symbol;Acc:HGNC:18327]",{"v":17.7027022593524,"d":"17.70"},{"v":36.060180848161,"d":"36.06"},{"v":0.490921061485891,"d":"0.49"},{"v":-1.02643703238091,"d":"-1.03"},{"v":0.130330131895319,"d":"0.13"},{"v":0.909550300721299,"d":"0.91"},"down","no"]
["ENSG00000119431","HDHD3","ENST00000238379;ENST00000374180;ENST00000485934","GO:0008152(metabolic process);GO:0016787(hydrolase activity);GO:0005515(protein binding);GO:0005739(mitochondrion);GO:0005739(mitochondrion)","NA","NA","NA","haloacid dehalogenase like hydrolase domain containing 3 [Source:HGNC Symbol;Acc:HGNC:28171]",{"v":1.49680478052257,"d":"1.50"},{"v":0.746020979097387,"d":"0.75"},{"v":2.00638430079213,"d":"2.01"},{"v":1.00459796474683,"d":"1.00"},{"v":0.13041397595293,"d":"0.13"},{"v":0.909550300721299,"d":"0.91"},"up","no"]
["MSTRG.1001","CREB3L4","ENST00000368607;ENST00000449724;ENST00000368600;ENST00000477617;ENST00000473340;ENST00000271889;ENST00000492729;ENST00000468845;ENST00000461688","GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0035497(cAMP response element binding);GO:0030968(endoplasmic reticulum unfolded protein response);GO:0005634(nucleus);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005654(nucleoplasm);GO:0006366(transcription from RNA polymerase II promoter);GO:0006351(transcription, DNA-templated);GO:0005739(mitochondrion);GO:0031965(nuclear membrane);GO:0005794(Golgi apparatus);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0000139(Golgi membrane);GO:0006986(response to unfolded protein);GO:0000977(RNA polymerase II regulatory region sequence-specific DNA binding);GO:0001228(transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding);GO:0007283(spermatogenesis);GO:0007283(spermatogenesis)","04668(TNF signaling pathway);04024(cAMP signaling pathway);04022(cGMP - PKG signaling pathway);04151(PI3K-Akt signaling pathway);04152(AMPK signaling pathway);04911(Insulin secretion);04922(Glucagon signaling pathway);04915(Estrogen signaling pathway);04926(Relaxin signaling pathway);04918(Thyroid hormone synthesis);04916(Melanogenesis);04925(Aldosterone synthesis and secretion);04927(Cortisol synthesis and secretion);04261(Adrenergic signaling in cardiomyocytes);04962(Vasopressin-regulated water reabsorption);04725(Cholinergic synapse);04728(Dopaminergic synapse);04211(Longevity regulating pathway - mammal);05203(Viral carcinogenesis);05215(Prostate cancer);05016(Huntington's disease);05030(Cocaine addiction);05031(Amphetamine addiction);05034(Alcoholism);04931(Insulin resistance);05161(Hepatitis B);05165(Human papillomavirus infection);05165(Human papillomavirus infection)","K09048","NA","cAMP responsive element binding protein 3 like 4 [Source:HGNC Symbol;Acc:HGNC:18854]",{"v":1.03414641873278,"d":"1.03"},{"v":0.512885382231405,"d":"0.51"},{"v":2.01633046009916,"d":"2.02"},{"v":1.01173210415338,"d":"1.01"},{"v":0.130442897304906,"d":"0.13"},{"v":0.909550300721299,"d":"0.91"},"up","no"]
["MSTRG.15114","CLIC3","ENST00000494426;ENST00000473911;ENST00000480181","GO:0006810(transport);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005244(voltage-gated ion channel activity);GO:0006811(ion transport);GO:0034765(regulation of ion transmembrane transport);GO:0005515(protein binding);GO:0016604(nuclear body);GO:0005254(chloride channel activity);GO:0006821(chloride transport);GO:0034707(chloride channel complex);GO:1902476(chloride transmembrane transport);GO:0070062(extracellular exosome);GO:0007165(signal transduction);GO:0007165(signal transduction)","NA","NA","NA","chloride intracellular channel 3 [Source:HGNC Symbol;Acc:HGNC:2064]",{"v":6.53486378164826,"d":"6.53"},{"v":3.29967672727273,"d":"3.30"},{"v":1.98045576029792,"d":"1.98"},{"v":0.985832474475727,"d":"0.99"},{"v":0.130770184906638,"d":"0.13"},{"v":0.910858854880111,"d":"0.91"},"up","no"]
["ENSG00000226784","PGAM4","ENST00000458128","GO:0016853(isomerase activity);GO:0016787(hydrolase activity);GO:0003824(catalytic activity);GO:0006096(glycolytic process);GO:0008152(metabolic process);GO:0004082(bisphosphoglycerate mutase activity);GO:0004619(phosphoglycerate mutase activity);GO:0016868(intramolecular transferase activity, phosphotransferases);GO:0070062(extracellular exosome);GO:0005829(cytosol);GO:0006094(gluconeogenesis);GO:0046538(2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity);GO:0043456(regulation of pentose-phosphate shunt);GO:0097228(sperm principal piece);GO:1902093(positive regulation of flagellated sperm motility)","00010(Glycolysis / Gluconeogenesis);00260(Glycine, serine and threonine metabolism);04922(Glucagon signaling pathway);05230(Central carbon metabolism in cancer)","K01834","EC:5.4.2.11","phosphoglycerate mutase family member 4 [Source:HGNC Symbol;Acc:HGNC:21731]",{"v":1.264446,"d":"1.26"},{"v":2.699926,"d":"2.70"},{"v":0.468326168939445,"d":"0.47"},{"v":-1.09441444027053,"d":"-1.09"},{"v":0.130781843554867,"d":"0.13"},{"v":0.910858854880111,"d":"0.91"},"down","no"]
["ENSG00000205784","ARRDC5","ENST00000381781","NA","NA","NA","NA","arrestin domain containing 5 [Source:HGNC Symbol;Acc:HGNC:31407]",{"v":1.106821,"d":"1.11"},{"v":0.536899,"d":"0.54"},{"v":2.06150691284581,"d":"2.06"},{"v":1.04369929901964,"d":"1.04"},{"v":0.130886280773667,"d":"0.13"},{"v":0.911059302356358,"d":"0.91"},"up","no"]
["MSTRG.15160","PRKX","ENST00000262848;ENST00000462736;ENST00000425240;ENST00000496648","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0007155(cell adhesion);GO:0005515(protein binding);GO:0007275(multicellular organism development);GO:0030154(cell differentiation);GO:0001525(angiogenesis);GO:0001935(endothelial cell proliferation);GO:0030334(regulation of cell migration);GO:0046777(protein autophosphorylation);GO:0030155(regulation of cell adhesion);GO:0043542(endothelial cell migration);GO:0031589(cell-substrate adhesion);GO:0018105(peptidyl-serine phosphorylation);GO:0004691(cAMP-dependent protein kinase activity);GO:0030099(myeloid cell differentiation);GO:0060562(epithelial tube morphogenesis);GO:0060993(kidney morphogenesis);GO:2000696(regulation of epithelial cell differentiation involved in kidney development);GO:2000696(regulation of epithelial cell differentiation involved in kidney development)","NA","NA","NA","protein kinase, X-linked [Source:HGNC Symbol;Acc:HGNC:9441]",{"v":8.10343257625543,"d":"8.10"},{"v":4.13091331261624,"d":"4.13"},{"v":1.9616564093724,"d":"1.96"},{"v":0.972072370862229,"d":"0.97"},{"v":0.131001641097199,"d":"0.13"},{"v":0.911117714878825,"d":"0.91"},"up","no"]
["ENSG00000133302","SLF1","ENST00000265140;ENST00000466957;ENST00000493934;ENST00000450932;ENST00000475916","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0000786(nucleosome);GO:0005856(cytoskeleton);GO:0006281(DNA repair);GO:0006974(cellular response to DNA damage stimulus);GO:0005813(centrosome);GO:0005815(microtubule organizing center);GO:0005515(protein binding);GO:0031625(ubiquitin protein ligase binding);GO:0032403(protein complex binding);GO:0031334(positive regulation of protein complex assembly);GO:0035861(site of double-strand break);GO:0042405(nuclear inclusion body);GO:2000781(positive regulation of double-strand break repair);GO:0034184(positive regulation of maintenance of mitotic sister chromatid cohesion);GO:1990166(protein localization to site of double-strand break);GO:1990166(protein localization to site of double-strand break)","NA","NA","NA","SMC5-SMC6 complex localization factor 1 [Source:HGNC Symbol;Acc:HGNC:25408]",{"v":0.405850753235908,"d":"0.41"},{"v":0.835596966040362,"d":"0.84"},{"v":0.485701563947881,"d":"0.49"},{"v":-1.04185796307335,"d":"-1.04"},{"v":0.131135874249198,"d":"0.13"},{"v":0.911117714878825,"d":"0.91"},"down","no"]
["MSTRG.3173","KLRC3","MSTRG.3173.1","NA","NA","NA","NA",null,{"v":6.800621,"d":"6.80"},{"v":3.285271,"d":"3.29"},{"v":2.0700334919098,"d":"2.07"},{"v":1.04965410986049,"d":"1.05"},{"v":0.131142799957471,"d":"0.13"},{"v":0.911117714878825,"d":"0.91"},"up","no"]
["MSTRG.6114","TXNL4B","ENST00000268483;ENST00000569767;ENST00000565171;ENST00000426362;ENST00000562153","GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0005681(spliceosomal complex);GO:0000398(mRNA splicing, via spliceosome);GO:0006397(mRNA processing);GO:0008380(RNA splicing);GO:0005634(nucleus);GO:0005515(protein binding);GO:0007049(cell cycle);GO:0005682(U5 snRNP);GO:0046540(U4/U6 x U5 tri-snRNP complex);GO:0000245(spliceosomal complex assembly);GO:0000245(spliceosomal complex assembly)","NA","NA","NA","thioredoxin like 4B [Source:HGNC Symbol;Acc:HGNC:26041]",{"v":2.98632864164038,"d":"2.99"},{"v":1.50555934700315,"d":"1.51"},{"v":1.98353432402697,"d":"1.98"},{"v":0.988073362784449,"d":"0.99"},{"v":0.131230976765892,"d":"0.13"},{"v":0.911117714878825,"d":"0.91"},"up","no"]
["ENSG00000176597","B3GNT5","ENST00000326505;ENST00000462559;ENST00000464191;ENST00000496270;ENST00000481531;ENST00000460419","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016740(transferase activity);GO:0016757(transferase activity, transferring glycosyl groups);GO:0006486(protein glycosylation);GO:0005794(Golgi apparatus);GO:0000139(Golgi membrane);GO:0007275(multicellular organism development);GO:0008378(galactosyltransferase activity);GO:0005622(intracellular);GO:0016266(O-glycan processing);GO:0007417(central nervous system development);GO:0008499(UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity);GO:0008457(beta-galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide beta-1,3-acetylglucosaminyltransferase activity);GO:0047256(lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase activity);GO:0007420(brain development);GO:0009247(glycolipid biosynthetic process);GO:0009247(glycolipid biosynthetic process)","00601(Glycosphingolipid biosynthesis - lacto and neolacto series);00601(Glycosphingolipid biosynthesis - lacto and neolacto series)","K03766","EC:2.4.1.206","UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5 [Source:HGNC Symbol;Acc:HGNC:15684]",{"v":0.3280832502457,"d":"0.33"},{"v":0.677125721867322,"d":"0.68"},{"v":0.484523390044819,"d":"0.48"},{"v":-1.0453617824211,"d":"-1.05"},{"v":0.131272980843279,"d":"0.13"},{"v":0.911117714878825,"d":"0.91"},"down","no"]
["MSTRG.12324","UBE2B","ENST00000265339;ENST00000511807;ENST00000503080;ENST00000504431;ENST00000507277;ENST00000499038;ENST00000510021;ENST00000506787","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0016740(transferase activity);GO:0016567(protein ubiquitination);GO:0005886(plasma membrane);GO:0006281(DNA repair);GO:0006974(cellular response to DNA damage stimulus);GO:0006511(ubiquitin-dependent protein catabolic process);GO:0007283(spermatogenesis);GO:0061630(ubiquitin protein ligase activity);GO:0005515(protein binding);GO:0005654(nucleoplasm);GO:0050821(protein stabilization);GO:0031625(ubiquitin protein ligase binding);GO:0004842(ubiquitin-protein transferase activity);GO:0009411(response to UV);GO:0000785(chromatin);GO:0043161(proteasome-mediated ubiquitin-dependent protein catabolic process);GO:0070534(protein K63-linked ubiquitination);GO:0070936(protein K48-linked ubiquitination);GO:0070979(protein K11-linked ubiquitination);GO:0060070(canonical Wnt signaling pathway);GO:0005657(replication fork);GO:0051865(protein autoubiquitination);GO:0000209(protein polyubiquitination);GO:0006513(protein monoubiquitination);GO:0043951(negative regulation of cAMP-mediated signaling);GO:0033503(HULC complex);GO:0033522(histone H2A ubiquitination);GO:0042493(response to drug);GO:0042769(DNA damage response, detection of DNA damage);GO:0006301(postreplication repair);GO:0061631(ubiquitin conjugating enzyme activity);GO:0001701(in utero embryonic development);GO:0006344(maintenance of chromatin silencing);GO:0007288(sperm axoneme assembly);GO:0010845(positive regulation of reciprocal meiotic recombination);GO:0031056(regulation of histone modification);GO:0033128(negative regulation of histone phosphorylation);GO:0043066(negative regulation of apoptotic process);GO:0045141(meiotic telomere clustering);GO:0051026(chiasma assembly);GO:0070076(histone lysine demethylation);GO:0070193(synaptonemal complex organization);GO:0000790(nuclear chromatin);GO:0001741(XY body);GO:0001741(XY body)","04120(Ubiquitin mediated proteolysis);04120(Ubiquitin mediated proteolysis)","K10574","EC:2.3.2.23","ubiquitin conjugating enzyme E2 B [Source:HGNC Symbol;Acc:HGNC:12473]",{"v":6.05387542752963,"d":"6.05"},{"v":12.3287223618961,"d":"12.33"},{"v":0.491038345241686,"d":"0.49"},{"v":-1.02609240572423,"d":"-1.03"},{"v":0.131384640100038,"d":"0.13"},{"v":0.911367417099457,"d":"0.91"},"down","no"]
["MSTRG.9193","TANK","ENST00000392749;ENST00000259075;ENST00000437623;ENST00000405852;ENST00000483622;ENST00000463502;ENST00000402568;ENST00000439442;ENST00000456358;ENST00000494976;ENST00000477952;ENST00000432002;ENST00000470324;ENST00000441987;ENST00000489393;ENST00000429217;ENST00000461338;ENST00000403609;ENST00000406287;ENST00000440506;ENST00000468831","GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0005829(cytosol);GO:0005515(protein binding);GO:0006508(proteolysis);GO:0006974(cellular response to DNA damage stimulus);GO:0043234(protein complex);GO:0071347(cellular response to interleukin-1);GO:0071356(cellular response to tumor necrosis factor);GO:0004843(thiol-dependent ubiquitin-specific protease activity);GO:0016032(viral process);GO:0031625(ubiquitin protein ligase binding);GO:0007165(signal transduction);GO:0035666(TRIF-dependent toll-like receptor signaling pathway);GO:0043124(negative regulation of I-kappaB kinase/NF-kappaB signaling);GO:0071479(cellular response to ionizing radiation);GO:1903003(positive regulation of protein deubiquitination);GO:0035800(deubiquitinase activator activity);GO:2000158(positive regulation of ubiquitin-specific protease activity);GO:0007249(I-kappaB kinase/NF-kappaB signaling);GO:0007249(I-kappaB kinase/NF-kappaB signaling)","04621(NOD-like receptor signaling pathway);04622(RIG-I-like receptor signaling pathway);04622(RIG-I-like receptor signaling pathway)","K12650","NA","TRAF family member associated NFKB activator [Source:HGNC Symbol;Acc:HGNC:11562]",{"v":5.62512683133178,"d":"5.63"},{"v":11.4307617935114,"d":"11.43"},{"v":0.492104282544392,"d":"0.49"},{"v":-1.02296402329093,"d":"-1.02"},{"v":0.131813260718151,"d":"0.13"},{"v":0.91367728757622,"d":"0.91"},"down","no"]
["MSTRG.5720","METTL9","ENST00000358154;ENST00000396014;ENST00000562961;ENST00000570074;ENST00000563026;ENST00000615720;ENST00000568826;ENST00000564733;ENST00000569290;ENST00000562379;ENST00000567404","GO:0005515(protein binding);GO:0005515(protein binding)","NA","NA","NA","methyltransferase like 9 [Source:HGNC Symbol;Acc:HGNC:24586]",{"v":4.87144439033404,"d":"4.87"},{"v":9.89610247505331,"d":"9.90"},{"v":0.492258887032978,"d":"0.49"},{"v":-1.02251084272159,"d":"-1.02"},{"v":0.131869384305553,"d":"0.13"},{"v":0.91367728757622,"d":"0.91"},"down","no"]
["MSTRG.13319","ADAT2","ENST00000606514;ENST00000367593;ENST00000237283","GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0008033(tRNA processing);GO:0016787(hydrolase activity);GO:0003824(catalytic activity);GO:0005515(protein binding);GO:0005654(nucleoplasm);GO:0006400(tRNA modification);GO:0008251(tRNA-specific adenosine deaminase activity);GO:0052717(tRNA-specific adenosine-34 deaminase activity);GO:0002100(tRNA wobble adenosine to inosine editing);GO:0052718(tRNA-specific adenosine-34 deaminase complex);GO:0052718(tRNA-specific adenosine-34 deaminase complex)","NA","NA","NA","adenosine deaminase, tRNA specific 2 [Source:HGNC Symbol;Acc:HGNC:21172]",{"v":0.483790306759582,"d":"0.48"},{"v":0.241165559303136,"d":"0.24"},{"v":2.00605056608218,"d":"2.01"},{"v":1.00435797210989,"d":"1.00"},{"v":0.132194525351519,"d":"0.13"},{"v":0.915245719058081,"d":"0.92"},"up","no"]
["ENSG00000211780","TRAV6","ENST00000390428","NA","NA","NA","NA","T-cell receptor alpha variable 6 [Source:HGNC Symbol;Acc:HGNC:12144]",{"v":7.899458,"d":"7.90"},{"v":3.931859,"d":"3.93"},{"v":2.00908984783025,"d":"2.01"},{"v":1.0065420837928,"d":"1.01"},{"v":0.132420948569392,"d":"0.13"},{"v":0.915245719058081,"d":"0.92"},"up","no"]
["ENSG00000185220","PGBD2","ENST00000329291;ENST00000355360","NA","NA","NA","NA","piggyBac transposable element derived 2 [Source:HGNC Symbol;Acc:HGNC:19399]",{"v":0.408619634072857,"d":"0.41"},{"v":0.849371031772117,"d":"0.85"},{"v":0.481084966154683,"d":"0.48"},{"v":-1.05563637880328,"d":"-1.06"},{"v":0.132549215756124,"d":"0.13"},{"v":0.915245719058081,"d":"0.92"},"down","no"]
["ENSG00000165997","ARL5B","ENST00000377275","GO:0005525(GTP binding);GO:0007264(small GTPase mediated signal transduction);GO:0000166(nucleotide binding);GO:0005622(intracellular)","NA","NA","NA","ADP ribosylation factor like GTPase 5B [Source:HGNC Symbol;Acc:HGNC:23052]",{"v":1.091329,"d":"1.09"},{"v":2.224617,"d":"2.22"},{"v":0.490569387899131,"d":"0.49"},{"v":-1.02747088403308,"d":"-1.03"},{"v":0.132640883069613,"d":"0.13"},{"v":0.915245719058081,"d":"0.92"},"down","no"]
["MSTRG.13324","LTV1;PHACTR2;AL049844.3;AL049844.1","ENST00000367576;ENST00000367584;ENST00000454207;ENST00000305766;ENST00000367582;ENST00000545614;ENST00000402863;ENST00000536245;ENST00000451827;ENST00000427704","GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0005515(protein binding);GO:0000056(ribosomal small subunit export from nucleus);GO:0042274(ribosomal small subunit biogenesis);GO:0005634(nucleus);GO:0030688(preribosome, small subunit precursor);GO:0031902(late endosome membrane);GO:0034448(EGO complex);GO:0006364(rRNA processing);GO:0003779(actin binding);GO:0043086(negative regulation of catalytic activity);GO:0004864(protein phosphatase inhibitor activity);GO:0016020(membrane);GO:0005886(plasma membrane);GO:0002576(platelet degranulation);GO:0031092(platelet alpha granule membrane);GO:0031092(platelet alpha granule membrane)","NA","NA","NA","LTV1 ribosome biogenesis factor [Source:HGNC Symbol;Acc:HGNC:21173];phosphatase and actin regulator 2 [Source:HGNC Symbol;Acc:HGNC:20956]",{"v":1.67457776877267,"d":"1.67"},{"v":0.854368913067287,"d":"0.85"},{"v":1.96001720469994,"d":"1.96"},{"v":0.970866318129435,"d":"0.97"},{"v":0.132649604442084,"d":"0.13"},{"v":0.915245719058081,"d":"0.92"},"up","no"]
["ENSG00000025434","NR1H3","ENST00000494018;ENST00000483882;ENST00000419652;ENST00000481020;ENST00000462051;ENST00000461778;ENST00000481889;ENST00000441012;ENST00000531660;ENST00000530310;ENST00000487913;ENST00000527949;ENST00000467728;ENST00000457932;ENST00000436778;ENST00000395397","GO:0050728(negative regulation of inflammatory response);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0042632(cholesterol homeostasis);GO:0071222(cellular response to lipopolysaccharide);GO:0005634(nucleus);GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0043565(sequence-specific DNA binding);GO:0005515(protein binding);GO:0003707(steroid hormone receptor activity);GO:0030522(intracellular receptor signaling pathway);GO:0043401(steroid hormone mediated signaling pathway);GO:0045893(positive regulation of transcription, DNA-templated);GO:0005654(nucleoplasm);GO:0003713(transcription coactivator activity);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0000790(nuclear chromatin);GO:0006367(transcription initiation from RNA polymerase II promoter);GO:0044212(transcription regulatory region DNA binding);GO:0090575(RNA polymerase II transcription factor complex);GO:0043277(apoptotic cell clearance);GO:0043235(receptor complex);GO:0032270(positive regulation of cellular protein metabolic process);GO:0015485(cholesterol binding);GO:0010745(negative regulation of macrophage derived foam cell differentiation);GO:0010875(positive regulation of cholesterol efflux);GO:0010887(negative regulation of cholesterol storage);GO:0004879(RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding);GO:0010867(positive regulation of triglyceride biosynthetic process);GO:0032570(response to progesterone);GO:0070328(triglyceride homeostasis);GO:0045723(positive regulation of fatty acid biosynthetic process);GO:0051006(positive regulation of lipoprotein lipase activity);GO:0032369(negative regulation of lipid transport);GO:0010870(positive regulation of receptor biosynthetic process);GO:0055088(lipid homeostasis);GO:0043031(negative regulation of macrophage activation);GO:0034145(positive regulation of toll-like receptor 4 signaling pathway);GO:2000188(regulation of cholesterol homeostasis);GO:0060336(negative regulation of interferon-gamma-mediated signaling pathway);GO:2000189(positive regulation of cholesterol homeostasis);GO:0032376(positive regulation of cholesterol transport);GO:0048550(negative regulation of pinocytosis);GO:0032810(sterol response element binding);GO:0042752(regulation of circadian rhythm);GO:0055092(sterol homeostasis);GO:0090188(negative regulation of pancreatic juice secretion);GO:0090341(negative regulation of secretion of lysosomal enzymes);GO:0006366(transcription from RNA polymerase II promoter);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:0001077(transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0044255(cellular lipid metabolic process);GO:0045861(negative regulation of proteolysis);GO:0045892(negative regulation of transcription, DNA-templated);GO:0045892(negative regulation of transcription, DNA-templated)","03320(PPAR signaling pathway);04932(Non-alcoholic fatty liver disease (NAFLD));04931(Insulin resistance);05160(Hepatitis C);05160(Hepatitis C)","K08536","NA","nuclear receptor subfamily 1 group H member 3 [Source:HGNC Symbol;Acc:HGNC:7966]",{"v":0.632691661592764,"d":"0.63"},{"v":0.305562313699537,"d":"0.31"},{"v":2.07058145990771,"d":"2.07"},{"v":1.05003596169987,"d":"1.05"},{"v":0.132714011541755,"d":"0.13"},{"v":0.915245719058081,"d":"0.92"},"up","no"]
["MSTRG.12373","IGIP","ENST00000333305","GO:0005576(extracellular region)","NA","NA","NA","IgA inducing protein [Source:HGNC Symbol;Acc:HGNC:33847]",{"v":0.8183,"d":"0.82"},{"v":0.407158,"d":"0.41"},{"v":2.00978489922831,"d":"2.01"},{"v":1.00704110268652,"d":"1.01"},{"v":0.132764447646712,"d":"0.13"},{"v":0.915245719058081,"d":"0.92"},"up","no"]
["MSTRG.13275","STX7","ENST00000367941;ENST00000475879;ENST00000367937","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0006886(intracellular protein transport);GO:0016192(vesicle-mediated transport);GO:0005765(lysosomal membrane);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0048471(perinuclear region of cytoplasm);GO:0065009(regulation of molecular function);GO:0005764(lysosome);GO:0006906(vesicle fusion);GO:0005484(SNAP receptor activity);GO:0005768(endosome);GO:0070062(extracellular exosome);GO:0005769(early endosome);GO:0005770(late endosome);GO:0031901(early endosome membrane);GO:0055037(recycling endosome);GO:0031201(SNARE complex);GO:0048278(vesicle docking);GO:0019905(syntaxin binding);GO:0042582(azurophil granule);GO:0070820(tertiary granule);GO:0031982(vesicle);GO:0000149(SNARE binding);GO:0019869(chloride channel inhibitor activity);GO:0001916(positive regulation of T cell mediated cytotoxicity);GO:0051640(organelle localization);GO:0070925(organelle assembly);GO:1902685(positive regulation of receptor localization to synapse);GO:1903076(regulation of protein localization to plasma membrane);GO:0001772(immunological synapse);GO:0030139(endocytic vesicle);GO:0030139(endocytic vesicle)","04130(SNARE interactions in vesicular transport);04145(Phagosome);04145(Phagosome)","K08488","NA","syntaxin 7 [Source:HGNC Symbol;Acc:HGNC:11442]",{"v":2.56657555129066,"d":"2.57"},{"v":5.20209373936657,"d":"5.20"},{"v":0.493373568390019,"d":"0.49"},{"v":-1.01924766699572,"d":"-1.02"},{"v":0.132767565674693,"d":"0.13"},{"v":0.915245719058081,"d":"0.92"},"down","no"]
["MSTRG.8771","CEP68","ENST00000377990;ENST00000497039;ENST00000537589","GO:0005737(cytoplasm);GO:0005634(nucleus);GO:0005829(cytosol);GO:0030054(cell junction);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0005815(microtubule organizing center);GO:0005813(centrosome);GO:0019901(protein kinase binding);GO:0007098(centrosome cycle);GO:0019904(protein domain specific binding);GO:0033365(protein localization to organelle);GO:0010457(centriole-centriole cohesion);GO:0010457(centriole-centriole cohesion)","NA","NA","NA","centrosomal protein 68 [Source:HGNC Symbol;Acc:HGNC:29076]",{"v":1.74575469511771,"d":"1.75"},{"v":0.887310357300244,"d":"0.89"},{"v":1.9674679561156,"d":"1.97"},{"v":0.97634013894517,"d":"0.98"},{"v":0.132779793322909,"d":"0.13"},{"v":0.915245719058081,"d":"0.92"},"up","no"]
["MSTRG.622","PDE4B","ENST00000371045;ENST00000480109;ENST00000526197;ENST00000483863;ENST00000534463;ENST00000423207;ENST00000528771;ENST00000524999","GO:0071222(cellular response to lipopolysaccharide);GO:0046872(metal ion binding);GO:0016787(hydrolase activity);GO:0007165(signal transduction);GO:0008081(phosphoric diester hydrolase activity);GO:0004114(3',5'-cyclic-nucleotide phosphodiesterase activity);GO:0005829(cytosol);GO:0044325(ion channel binding);GO:0032729(positive regulation of interferon-gamma production);GO:0004115(3',5'-cyclic-AMP phosphodiesterase activity);GO:0006198(cAMP catabolic process);GO:0005891(voltage-gated calcium channel complex);GO:0030018(Z disc);GO:1901841(regulation of high voltage-gated calcium channel activity);GO:0030593(neutrophil chemotaxis);GO:0001780(neutrophil homeostasis);GO:0050900(leukocyte migration);GO:0071872(cellular response to epinephrine stimulus);GO:0086004(regulation of cardiac muscle cell contraction);GO:0030552(cAMP binding);GO:0032743(positive regulation of interleukin-2 production);GO:0035690(cellular response to drug);GO:0043015(gamma-tubulin binding);GO:0050852(T cell receptor signaling pathway);GO:1901898(negative regulation of relaxation of cardiac muscle);GO:0000930(gamma-tubulin complex);GO:0005813(centrosome);GO:0008021(synaptic vesicle);GO:0014069(postsynaptic density);GO:0016020(membrane);GO:0043197(dendritic spine);GO:0060076(excitatory synapse);GO:0071944(cell periphery);GO:0071944(cell periphery)","00230(Purine metabolism);04024(cAMP signaling pathway);05032(Morphine addiction);05032(Morphine addiction)","K13293","EC:3.1.4.53","phosphodiesterase 4B [Source:HGNC Symbol;Acc:HGNC:8781]",{"v":2.87842405842203,"d":"2.88"},{"v":5.84134651469227,"d":"5.84"},{"v":0.492767215775021,"d":"0.49"},{"v":-1.02102181939866,"d":"-1.02"},{"v":0.132940829810238,"d":"0.13"},{"v":0.915279122246129,"d":"0.92"},"down","no"]
["MSTRG.4134","RNASE6","ENST00000304677","GO:0003676(nucleic acid binding);GO:0016787(hydrolase activity);GO:0090305(nucleic acid phosphodiester bond hydrolysis);GO:0005576(extracellular region);GO:0004519(endonuclease activity);GO:0004518(nuclease activity);GO:0005615(extracellular space);GO:0031410(cytoplasmic vesicle);GO:0045087(innate immune response);GO:0051607(defense response to virus);GO:0070062(extracellular exosome);GO:0050829(defense response to Gram-negative bacterium);GO:0005622(intracellular);GO:0019731(antibacterial humoral response);GO:0050830(defense response to Gram-positive bacterium);GO:0061844(antimicrobial humoral immune response mediated by antimicrobial peptide);GO:0019730(antimicrobial humoral response);GO:0004540(ribonuclease activity);GO:0006401(RNA catabolic process);GO:0006952(defense response);GO:0090501(RNA phosphodiester bond hydrolysis)","NA","NA","NA","ribonuclease A family member k6 [Source:HGNC Symbol;Acc:HGNC:10048]",{"v":8.561379,"d":"8.56"},{"v":17.38961,"d":"17.39"},{"v":0.49232725748306,"d":"0.49"},{"v":-1.0223104789241,"d":"-1.02"},{"v":0.132954335708966,"d":"0.13"},{"v":0.915279122246129,"d":"0.92"},"down","no"]
["MSTRG.3501","TSPAN31","ENST00000257910;ENST00000550791;ENST00000552816;ENST00000553089;ENST00000547311;ENST00000553221;ENST00000547992;ENST00000547472;ENST00000549052;ENST00000546922;ENST00000546993","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0007166(cell surface receptor signaling pathway);GO:0005887(integral component of plasma membrane);GO:0008284(positive regulation of cell proliferation);GO:0008284(positive regulation of cell proliferation)","NA","NA","NA","tetraspanin 31 [Source:HGNC Symbol;Acc:HGNC:10539]",{"v":0.233969342989786,"d":"0.23"},{"v":0.490498096750232,"d":"0.49"},{"v":0.477003569514208,"d":"0.48"},{"v":-1.06792803263733,"d":"-1.07"},{"v":0.133012661014011,"d":"0.13"},{"v":0.915279122246129,"d":"0.92"},"down","no"]
["MSTRG.12966","HMGA1","ENST00000401473;ENST00000311487;ENST00000347617;ENST00000447654;ENST00000374116;ENST00000478214","GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0005634(nucleus);GO:0006355(regulation of transcription, DNA-templated);GO:0006366(transcription from RNA polymerase II promoter);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0005694(chromosome);GO:0000785(chromatin);GO:0030374(ligand-dependent nuclear receptor transcription coactivator activity);GO:0045893(positive regulation of transcription, DNA-templated);GO:0005925(focal adhesion);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0005515(protein binding);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0008285(negative regulation of cell proliferation);GO:0042974(retinoic acid receptor binding);GO:0009615(response to virus);GO:0016032(viral process);GO:0006284(base-excision repair);GO:0019899(enzyme binding);GO:0008134(transcription factor binding);GO:0045892(negative regulation of transcription, DNA-templated);GO:0003682(chromatin binding);GO:0090575(RNA polymerase II transcription factor complex);GO:0006461(protein complex assembly);GO:0005667(transcription factor complex);GO:0051169(nuclear transport);GO:0075713(establishment of integrated proviral latency);GO:0001205(transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding);GO:0006337(nucleosome disassembly);GO:0001158(enhancer sequence-specific DNA binding);GO:0003680(AT DNA binding);GO:0003906(DNA-(apurinic or apyrimidinic site) lyase activity);GO:0042975(peroxisome proliferator activated receptor binding);GO:0046965(retinoid X receptor binding);GO:0006268(DNA unwinding involved in DNA replication);GO:0031936(negative regulation of chromatin silencing);GO:0035986(senescence-associated heterochromatin focus assembly);GO:0090402(oncogene-induced cell senescence);GO:2000774(positive regulation of cellular senescence);GO:0035985(senescence-associated heterochromatin focus);GO:0035985(senescence-associated heterochromatin focus)","NA","NA","NA","high mobility group AT-hook 1 [Source:HGNC Symbol;Acc:HGNC:5010]",{"v":12.7377786012033,"d":"12.74"},{"v":25.8134572780404,"d":"25.81"},{"v":0.493454962812725,"d":"0.49"},{"v":-1.01900967766617,"d":"-1.02"},{"v":0.133239120541777,"d":"0.13"},{"v":0.915668445107918,"d":"0.92"},"down","no"]
["ENSG00000118518","RNF146","ENST00000610153;ENST00000368314;ENST00000609944;ENST00000608340;ENST00000356799;ENST00000609447;ENST00000610162;ENST00000309649;ENST00000489534;ENST00000608991;ENST00000476956;ENST00000480444;ENST00000495188","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0016740(transferase activity);GO:0016567(protein ubiquitination);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0061630(ubiquitin protein ligase activity);GO:0016055(Wnt signaling pathway);GO:0016579(protein deubiquitination);GO:0090263(positive regulation of canonical Wnt signaling pathway);GO:0042787(protein ubiquitination involved in ubiquitin-dependent protein catabolic process);GO:0004842(ubiquitin-protein transferase activity);GO:0070936(protein K48-linked ubiquitination);GO:0051865(protein autoubiquitination);GO:0072572(poly-ADP-D-ribose binding);GO:0072572(poly-ADP-D-ribose binding)","NA","NA","NA","ring finger protein 146 [Source:HGNC Symbol;Acc:HGNC:21336]",{"v":2.88544106670467,"d":"2.89"},{"v":5.86548692588369,"d":"5.87"},{"v":0.491935469836539,"d":"0.49"},{"v":-1.02345901398264,"d":"-1.02"},{"v":0.133247175180428,"d":"0.13"},{"v":0.915668445107918,"d":"0.92"},"down","no"]
["MSTRG.3704","ANKRD13A","MSTRG.3704.4;ENST00000261739;ENST00000553251;ENST00000546476;ENST00000550404;ENST00000549826;ENST00000553025;ENST00000547639;ENST00000551491;ENST00000553246","GO:0016020(membrane);GO:0005886(plasma membrane);GO:0005737(cytoplasm);GO:0005768(endosome);GO:0005770(late endosome);GO:0005770(late endosome)","NA","NA","NA","ankyrin repeat domain 13A [Source:HGNC Symbol;Acc:HGNC:21268]",{"v":8.69246730081633,"d":"8.69"},{"v":17.6029953578231,"d":"17.60"},{"v":0.493806146290508,"d":"0.49"},{"v":-1.01798330140454,"d":"-1.02"},{"v":0.133297948663649,"d":"0.13"},{"v":0.915668445107918,"d":"0.92"},"down","no"]
["MSTRG.11336",null,"MSTRG.11336.1","NA","NA","NA","NA",null,{"v":5.29946,"d":"5.30"},{"v":2.677755,"d":"2.68"},{"v":1.97906828668045,"d":"1.98"},{"v":0.984821392656059,"d":"0.98"},{"v":0.133373397502017,"d":"0.13"},{"v":0.915668445107918,"d":"0.92"},"up","no"]
["MSTRG.14813","GNAQ","ENST00000286548;ENST00000411677","GO:0005634(nucleus);GO:0016020(membrane);GO:0005525(GTP binding);GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0007186(G-protein coupled receptor signaling pathway);GO:0007165(signal transduction);GO:0003924(GTPase activity);GO:0004871(signal transducer activity);GO:0005765(lysosomal membrane);GO:0043547(positive regulation of GTPase activity);GO:0005515(protein binding);GO:0001664(G-protein coupled receptor binding);GO:0019001(guanyl nucleotide binding);GO:0031683(G-protein beta/gamma-subunit complex binding);GO:0001501(skeletal system development);GO:0001508(action potential);GO:0007189(adenylate cyclase-activating G-protein coupled receptor signaling pathway);GO:0007213(G-protein coupled acetylcholine receptor signaling pathway);GO:0007215(glutamate receptor signaling pathway);GO:0007507(heart development);GO:0007603(phototransduction, visible light);GO:0009649(entrainment of circadian clock);GO:0009791(post-embryonic development);GO:0016322(neuron remodeling);GO:0021884(forebrain neuron development);GO:0042711(maternal behavior);GO:0042733(embryonic digit morphogenesis);GO:0045634(regulation of melanocyte differentiation);GO:0048066(developmental pigmentation);GO:0060158(phospholipase C-activating dopamine receptor signaling pathway);GO:0001750(photoreceptor outer segment);GO:0030425(dendrite);GO:0044297(cell body);GO:0005096(GTPase activator activity);GO:0005886(plasma membrane);GO:0070062(extracellular exosome);GO:0005834(heterotrimeric G-protein complex);GO:0031965(nuclear membrane);GO:0005737(cytoplasm);GO:0007596(blood coagulation);GO:0030168(platelet activation);GO:0050821(protein stabilization);GO:0006469(negative regulation of protein kinase activity);GO:0035412(regulation of catenin import into nucleus);GO:0007202(activation of phospholipase C activity);GO:0031826(type 2A serotonin receptor binding);GO:0031826(type 2A serotonin receptor binding)","04015(Rap1 signaling pathway);04371(Apelin signaling pathway);04020(Calcium signaling pathway);04071(Sphingolipid signaling pathway);04022(cGMP - PKG signaling pathway);04540(Gap junction);04611(Platelet activation);04911(Insulin secretion);04922(Glucagon signaling pathway);04912(GnRH signaling pathway);04915(Estrogen signaling pathway);04921(Oxytocin signaling pathway);04918(Thyroid hormone synthesis);04916(Melanogenesis);04924(Renin secretion);04925(Aldosterone synthesis and secretion);04927(Cortisol synthesis and secretion);04261(Adrenergic signaling in cardiomyocytes);04270(Vascular smooth muscle contraction);04970(Salivary secretion);04971(Gastric acid secretion);04972(Pancreatic secretion);04961(Endocrine and other factor-regulated calcium reabsorption);04724(Glutamatergic synapse);04725(Cholinergic synapse);04728(Dopaminergic synapse);04726(Serotonergic synapse);04720(Long-term potentiation);04730(Long-term depression);04723(Retrograde endocannabinoid signaling);04750(Inflammatory mediator regulation of TRP channels);04713(Circadian entrainment);05200(Pathways in cancer);05010(Alzheimer's disease);05016(Huntington's disease);05146(Amoebiasis);05142(Chagas disease (American trypanosomiasis));05143(African trypanosomiasis);05143(African trypanosomiasis)","K04634","NA","G protein subunit alpha q [Source:HGNC Symbol;Acc:HGNC:4390]",{"v":7.26518771881128,"d":"7.27"},{"v":14.7088092389501,"d":"14.71"},{"v":0.493934457969071,"d":"0.49"},{"v":-1.01760847703751,"d":"-1.02"},{"v":0.133457198629183,"d":"0.13"},{"v":0.915721701363315,"d":"0.92"},"down","no"]
["ENSG00000100523","DDHD1","ENST00000557445;ENST00000555400;ENST00000553406;ENST00000395606;ENST00000612692;ENST00000555621;ENST00000357758;ENST00000556027;ENST00000323669","GO:0005737(cytoplasm);GO:0016787(hydrolase activity);GO:0046872(metal ion binding);GO:0006629(lipid metabolic process);GO:0016042(lipid catabolic process);GO:0005829(cytosol);GO:0006654(phosphatidic acid biosynthetic process);GO:0004620(phospholipase activity);GO:0090141(positive regulation of mitochondrial fission);GO:0090141(positive regulation of mitochondrial fission)","NA","NA","NA","DDHD domain containing 1 [Source:HGNC Symbol;Acc:HGNC:19714]",{"v":0.670074344906375,"d":"0.67"},{"v":0.342277799765938,"d":"0.34"},{"v":1.9576915165535,"d":"1.96"},{"v":0.96915345002801,"d":"0.97"},{"v":0.133589078046957,"d":"0.13"},{"v":0.916104600137502,"d":"0.92"},"up","no"]
["MSTRG.2801","AP000787.1","ENST00000545216;ENST00000501356;ENST00000543150;ENST00000543573;ENST00000540692;ENST00000536683;ENST00000534891;ENST00000534864","NA","NA","NA","NA",null,{"v":0.404286666729323,"d":"0.40"},{"v":0.197239362593985,"d":"0.20"},{"v":2.04972608617451,"d":"2.05"},{"v":1.03543112898881,"d":"1.04"},{"v":0.133685499623825,"d":"0.13"},{"v":0.91624404466141,"d":"0.92"},"up","no"]
["MSTRG.4072","TM9SF2","ENST00000376387;ENST00000466555;ENST00000463709","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005768(endosome);GO:0070062(extracellular exosome);GO:0010008(endosome membrane);GO:0006810(transport);GO:0005887(integral component of plasma membrane);GO:0005887(integral component of plasma membrane)","NA","NA","NA","transmembrane 9 superfamily member 2 [Source:HGNC Symbol;Acc:HGNC:11865]",{"v":12.6448290223938,"d":"12.64"},{"v":25.5762360460746,"d":"25.58"},{"v":0.494397572794317,"d":"0.49"},{"v":-1.0162564344246,"d":"-1.02"},{"v":0.133896700475516,"d":"0.13"},{"v":0.916632959970347,"d":"0.92"},"down","no"]
["MSTRG.12520","PTTG1","ENST00000393964;ENST00000517480;ENST00000352433;ENST00000523659;ENST00000520452","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0051301(cell division);GO:0010951(negative regulation of endopeptidase activity);GO:0051276(chromosome organization);GO:0006281(DNA repair);GO:0006974(cellular response to DNA damage stimulus);GO:0007049(cell cycle);GO:0006355(regulation of transcription, DNA-templated);GO:0004869(cysteine-type endopeptidase inhibitor activity);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0007059(chromosome segregation);GO:0010466(negative regulation of peptidase activity);GO:0005515(protein binding);GO:0005829(cytosol);GO:0031145(anaphase-promoting complex-dependent catabolic process);GO:0017124(SH3 domain binding);GO:0006366(transcription from RNA polymerase II promoter);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0007283(spermatogenesis);GO:0042787(protein ubiquitination involved in ubiquitin-dependent protein catabolic process);GO:0000981(RNA polymerase II transcription factor activity, sequence-specific DNA binding);GO:0030414(peptidase inhibitor activity);GO:0045143(homologous chromosome segregation);GO:2000816(negative regulation of mitotic sister chromatid separation);GO:2000816(negative regulation of mitotic sister chromatid separation)","04110(Cell cycle);04114(Oocyte meiosis);05166(HTLV-I infection);05166(HTLV-I infection)","K06635","NA","pituitary tumor-transforming 1 [Source:HGNC Symbol;Acc:HGNC:9690]",{"v":1.74983110829608,"d":"1.75"},{"v":0.872997597615499,"d":"0.87"},{"v":2.00439395603786,"d":"2.00"},{"v":1.00316609264697,"d":"1.00"},{"v":0.13398510891001,"d":"0.13"},{"v":0.916632959970347,"d":"0.92"},"up","no"]
["MSTRG.12419","ARHGAP26","ENST00000378004;ENST00000274498;ENST00000418236;ENST00000461314;ENST00000489924;ENST00000477867;ENST00000443045;ENST00000464838;ENST00000469396;ENST00000425417;ENST00000475287;ENST00000486650;ENST00000419676;ENST00000424007;ENST00000470032","GO:0005737(cytoplasm);GO:0007165(signal transduction);GO:0043547(positive regulation of GTPase activity);GO:0030036(actin cytoskeleton organization);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0005096(GTPase activator activity);GO:0030054(cell junction);GO:0007399(nervous system development);GO:0051056(regulation of small GTPase mediated signal transduction);GO:0005925(focal adhesion);GO:0005575(cellular_component);GO:0005829(cytosol);GO:0005543(phospholipid binding);GO:0005543(phospholipid binding)","NA","NA","NA","Rho GTPase activating protein 26 [Source:HGNC Symbol;Acc:HGNC:17073]",{"v":4.41257302464973,"d":"4.41"},{"v":8.92175281771185,"d":"8.92"},{"v":0.494585886294642,"d":"0.49"},{"v":-1.01570702390851,"d":"-1.02"},{"v":0.13411742104637,"d":"0.13"},{"v":0.916632959970347,"d":"0.92"},"down","no"]
["ENSG00000121454","LHX4","ENST00000263726","GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006355(regulation of transcription, DNA-templated);GO:0006366(transcription from RNA polymerase II promoter);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0043565(sequence-specific DNA binding);GO:0005515(protein binding);GO:0001890(placenta development);GO:0008045(motor neuron axon guidance);GO:0009887(animal organ morphogenesis);GO:0021526(medial motor column neuron differentiation);GO:0043066(negative regulation of apoptotic process);GO:0005622(intracellular);GO:0001228(transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding);GO:0045944(positive regulation of transcription from RNA polymerase II promoter)","NA","NA","NA","LIM homeobox 4 [Source:HGNC Symbol;Acc:HGNC:21734]",{"v":0.316447256228345,"d":"0.32"},{"v":0.157114073585217,"d":"0.16"},{"v":2.0141241901968,"d":"2.01"},{"v":1.01015264216158,"d":"1.01"},{"v":0.134155362393904,"d":"0.13"},{"v":0.916632959970347,"d":"0.92"},"up","no"]
["MSTRG.12628","SERPINB1","MSTRG.12628.2;ENST00000380739;ENST00000468511;ENST00000476896;ENST00000490094;ENST00000460260","GO:0005615(extracellular space);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0004867(serine-type endopeptidase inhibitor activity);GO:0010951(negative regulation of endopeptidase activity);GO:0005576(extracellular region);GO:0030414(peptidase inhibitor activity);GO:0010466(negative regulation of peptidase activity);GO:0070062(extracellular exosome);GO:0043312(neutrophil degranulation);GO:0034774(secretory granule lumen);GO:0034774(secretory granule lumen)","05146(Amoebiasis);05146(Amoebiasis)","K13963","NA","serpin family B member 1 [Source:HGNC Symbol;Acc:HGNC:3311]",{"v":14.0754748214401,"d":"14.08"},{"v":28.4678695282531,"d":"28.47"},{"v":0.4944337266781,"d":"0.49"},{"v":-1.01615093811013,"d":"-1.02"},{"v":0.134205550910231,"d":"0.13"},{"v":0.916632959970347,"d":"0.92"},"down","no"]
["MSTRG.2858","AP002518.2","MSTRG.2858.1","NA","NA","NA","NA",null,{"v":8.157501,"d":"8.16"},{"v":4.158916,"d":"4.16"},{"v":1.96144884869038,"d":"1.96"},{"v":0.971919712828748,"d":"0.97"},{"v":0.134254308899608,"d":"0.13"},{"v":0.916632959970347,"d":"0.92"},"up","no"]
["MSTRG.2553","LTBP3","ENST00000527792;ENST00000525443;ENST00000301873;ENST00000530785;ENST00000528966;ENST00000529764;ENST00000322147;ENST00000530990;ENST00000528516;ENST00000524798;ENST00000527339;ENST00000530866;ENST00000526124;ENST00000529371;ENST00000532932;ENST00000529582;ENST00000532661;ENST00000529189","GO:0005509(calcium ion binding);GO:0005576(extracellular region);GO:0070062(extracellular exosome);GO:0031012(extracellular matrix);GO:0019838(growth factor binding);GO:2000741(positive regulation of mesenchymal stem cell differentiation);GO:0050431(transforming growth factor beta binding);GO:0036363(transforming growth factor beta activation);GO:1902462(positive regulation of mesenchymal stem cell proliferation);GO:1902462(positive regulation of mesenchymal stem cell proliferation)","NA","NA","NA","latent transforming growth factor beta binding protein 3 [Source:HGNC Symbol;Acc:HGNC:6716]",{"v":3.19032741241018,"d":"3.19"},{"v":1.63111835230142,"d":"1.63"},{"v":1.95591411739608,"d":"1.96"},{"v":0.967843024110719,"d":"0.97"},{"v":0.134275082327495,"d":"0.13"},{"v":0.916632959970347,"d":"0.92"},"up","no"]
["ENSG00000154358","OBSCN","ENST00000284548;ENST00000570156;ENST00000483539;ENST00000636476;ENST00000422127;ENST00000366706;ENST00000494839;ENST00000366704;ENST00000474237;ENST00000602685;ENST00000602832","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0005829(cytosol);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0005886(plasma membrane);GO:0005089(Rho guanyl-nucleotide exchange factor activity);GO:0035023(regulation of Rho protein signal transduction);GO:0043547(positive regulation of GTPase activity);GO:0005515(protein binding);GO:0016604(nuclear body);GO:0007275(multicellular organism development);GO:0030154(cell differentiation);GO:0005516(calmodulin binding);GO:0051056(regulation of small GTPase mediated signal transduction);GO:0042383(sarcolemma);GO:0031430(M band);GO:0030018(Z disc);GO:0005085(guanyl-nucleotide exchange factor activity);GO:0043065(positive regulation of apoptotic process);GO:0008307(structural constituent of muscle);GO:0031432(titin binding);GO:0045214(sarcomere organization);GO:0030506(ankyrin binding);GO:0030016(myofibril);GO:0036309(protein localization to M-band);GO:0030017(sarcomere);GO:0030017(sarcomere)","NA","NA","NA","obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF [Source:HGNC Symbol;Acc:HGNC:15719]",{"v":0.966414164602044,"d":"0.97"},{"v":0.49510545023227,"d":"0.50"},{"v":1.95193602524203,"d":"1.95"},{"v":0.964905769305231,"d":"0.96"},{"v":0.134427896144459,"d":"0.13"},{"v":0.917156218340833,"d":"0.92"},"up","no"]
["ENSG00000230438","SERPINB9P1","ENST00000545177;ENST00000420981","NA","NA","NA","NA","serpin family B member 9 pseudogene 1 [Source:HGNC Symbol;Acc:HGNC:28590]",{"v":2.09543219178082,"d":"2.10"},{"v":1.04845256849315,"d":"1.05"},{"v":1.99859512461532,"d":"2.00"},{"v":0.998986240531598,"d":"1.00"},{"v":0.134657827401436,"d":"0.13"},{"v":0.918204732484762,"d":"0.92"},"up","no"]
["ENSG00000184371","CSF1","ENST00000329608;ENST00000527192;ENST00000420111;ENST00000369802","GO:0016021(integral component of membrane);GO:0008083(growth factor activity);GO:0005125(cytokine activity);GO:0005615(extracellular space);GO:0010628(positive regulation of gene expression);GO:0048471(perinuclear region of cytoplasm);GO:0030335(positive regulation of cell migration);GO:0016020(membrane);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0030154(cell differentiation);GO:0002376(immune system process);GO:0045087(innate immune response);GO:0006954(inflammatory response);GO:0070062(extracellular exosome);GO:0044267(cellular protein metabolic process);GO:0043687(post-translational protein modification);GO:0008283(cell proliferation);GO:0008284(positive regulation of cell proliferation);GO:0042803(protein homodimerization activity);GO:0005788(endoplasmic reticulum lumen);GO:0030097(hemopoiesis);GO:0001954(positive regulation of cell-matrix adhesion);GO:0045860(positive regulation of protein kinase activity);GO:0042117(monocyte activation);GO:0030316(osteoclast differentiation);GO:0045672(positive regulation of osteoclast differentiation);GO:0010744(positive regulation of macrophage derived foam cell differentiation);GO:0032270(positive regulation of cellular protein metabolic process);GO:0045651(positive regulation of macrophage differentiation);GO:0007169(transmembrane receptor protein tyrosine kinase signaling pathway);GO:0030225(macrophage differentiation);GO:1990682(CSF1-CSF1R complex);GO:0010759(positive regulation of macrophage chemotaxis);GO:0005157(macrophage colony-stimulating factor receptor binding);GO:0002158(osteoclast proliferation);GO:0003006(developmental process involved in reproduction);GO:0010743(regulation of macrophage derived foam cell differentiation);GO:0030278(regulation of ossification);GO:0032946(positive regulation of mononuclear cell proliferation);GO:0038145(macrophage colony-stimulating factor signaling pathway);GO:0040018(positive regulation of multicellular organism growth);GO:0042488(positive regulation of odontogenesis of dentin-containing tooth);GO:0045657(positive regulation of monocyte differentiation);GO:0046579(positive regulation of Ras protein signal transduction);GO:0048873(homeostasis of number of cells within a tissue);GO:0060444(branching involved in mammary gland duct morphogenesis);GO:0060611(mammary gland fat development);GO:0060763(mammary duct terminal end bud growth);GO:1902228(positive regulation of macrophage colony-stimulating factor signaling pathway);GO:1904141(positive regulation of microglial cell migration);GO:1904141(positive regulation of microglial cell migration)","04014(Ras signaling pathway);04015(Rap1 signaling pathway);04010(MAPK signaling pathway);04668(TNF signaling pathway);04151(PI3K-Akt signaling pathway);04060(Cytokine-cytokine receptor interaction);04640(Hematopoietic cell lineage);04380(Osteoclast differentiation);05323(Rheumatoid arthritis);05323(Rheumatoid arthritis)","K05453","NA","colony stimulating factor 1 [Source:HGNC Symbol;Acc:HGNC:2432]",{"v":0.853807029346622,"d":"0.85"},{"v":1.74049301439646,"d":"1.74"},{"v":0.490554700469563,"d":"0.49"},{"v":-1.02751407832838,"d":"-1.03"},{"v":0.134809438411254,"d":"0.13"},{"v":0.918595305820737,"d":"0.92"},"down","no"]
["MSTRG.15204","SAT1","ENST00000487713;ENST00000474223;ENST00000379253;ENST00000489394;ENST00000379270;MSTRG.15204.1;ENST00000462639;ENST00000463236;ENST00000379254;ENST00000379251","GO:0004145(diamine N-acetyltransferase activity);GO:0008080(N-acetyltransferase activity);GO:0005737(cytoplasm);GO:0016740(transferase activity);GO:0016746(transferase activity, transferring acyl groups);GO:0005515(protein binding);GO:0005829(cytosol);GO:0001525(angiogenesis);GO:0005622(intracellular);GO:0019809(spermidine binding);GO:0006595(polyamine metabolic process);GO:0006596(polyamine biosynthetic process);GO:0006598(polyamine catabolic process);GO:0009447(putrescine catabolic process);GO:0032918(spermidine acetylation);GO:0042127(regulation of cell proliferation);GO:0046208(spermine catabolic process);GO:0046208(spermine catabolic process)","00330(Arginine and proline metabolism);04216(Ferroptosis);04216(Ferroptosis)","K00657","EC:2.3.1.57","spermidine/spermine N1-acetyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:10540]",{"v":32.6546844951962,"d":"32.65"},{"v":65.9168080144115,"d":"65.92"},{"v":0.495392381379524,"d":"0.50"},{"v":-1.01335641328431,"d":"-1.01"},{"v":0.134922753564518,"d":"0.13"},{"v":0.918595305820737,"d":"0.92"},"down","no"]
["ENSG00000160352","ZNF714","ENST00000600535;ENST00000610902;ENST00000456283;ENST00000596053;ENST00000620627;ENST00000613286;ENST00000618008","GO:0003676(nucleic acid binding);GO:0006355(regulation of transcription, DNA-templated);GO:0005622(intracellular);GO:0046872(metal ion binding);GO:0046872(metal ion binding)","NA","NA","NA","zinc finger protein 714 [Source:HGNC Symbol;Acc:HGNC:27124]",{"v":0.35589762230798,"d":"0.36"},{"v":0.179457752396365,"d":"0.18"},{"v":1.98318332618986,"d":"1.98"},{"v":0.987818046986889,"d":"0.99"},{"v":0.13494395416018,"d":"0.13"},{"v":0.918595305820737,"d":"0.92"},"up","no"]
["MSTRG.6839","RETREG3","ENST00000309428;ENST00000589797;ENST00000588423;ENST00000585726;ENST00000589007;ENST00000586870;ENST00000586796;ENST00000591547;ENST00000590035;ENST00000593251;ENST00000585894","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0010976(positive regulation of neuron projection development);GO:0005515(protein binding);GO:0005515(protein binding)","NA","NA","NA","reticulophagy regulator family member 3 [Source:HGNC Symbol;Acc:HGNC:27258]",{"v":4.38923203226433,"d":"4.39"},{"v":2.24817688726919,"d":"2.25"},{"v":1.95235172869152,"d":"1.95"},{"v":0.965212987084824,"d":"0.97"},{"v":0.135194798078705,"d":"0.14"},{"v":0.919478193142111,"d":"0.92"},"up","no"]
["MSTRG.11741","LAMTOR3","ENST00000499666;ENST00000226522;ENST00000515100","GO:0016020(membrane);GO:0043547(positive regulation of GTPase activity);GO:0005515(protein binding);GO:0005925(focal adhesion);GO:0005085(guanyl-nucleotide exchange factor activity);GO:0005886(plasma membrane);GO:0071230(cellular response to amino acid stimulus);GO:0005768(endosome);GO:0031902(late endosome membrane);GO:0070062(extracellular exosome);GO:0010008(endosome membrane);GO:0000165(MAPK cascade);GO:0043312(neutrophil degranulation);GO:0035579(specific granule membrane);GO:0070821(tertiary granule membrane);GO:0005765(lysosomal membrane);GO:0032008(positive regulation of TOR signaling);GO:0032947(protein complex scaffold);GO:0007050(cell cycle arrest);GO:0016241(regulation of macroautophagy);GO:0071986(Ragulator complex);GO:0034613(cellular protein localization);GO:0019209(kinase activator activity);GO:0000186(activation of MAPKK activity);GO:0032006(regulation of TOR signaling);GO:0005770(late endosome);GO:0005770(late endosome)","04010(MAPK signaling pathway);04150(mTOR signaling pathway);04150(mTOR signaling pathway)","K04370","NA","late endosomal/lysosomal adaptor, MAPK and MTOR activator 3 [Source:HGNC Symbol;Acc:HGNC:15606]",{"v":2.32431477993374,"d":"2.32"},{"v":4.71039478821581,"d":"4.71"},{"v":0.4934437312449,"d":"0.49"},{"v":-1.01904251533695,"d":"-1.02"},{"v":0.135406901230845,"d":"0.14"},{"v":0.919478193142111,"d":"0.92"},"down","no"]
["MSTRG.4636","IFI27L1","ENST00000556381;ENST00000555523;ENST00000393115;ENST00000557600;ENST00000555065;ENST00000554166;ENST00000554562;ENST00000555341;ENST00000557066;ENST00000553664","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016021(integral component of membrane)","NA","NA","NA","interferon alpha inducible protein 27 like 1 [Source:HGNC Symbol;Acc:HGNC:19754]",{"v":0.59493418697479,"d":"0.59"},{"v":0.296331458823529,"d":"0.30"},{"v":2.00766462439307,"d":"2.01"},{"v":1.00551829063567,"d":"1.01"},{"v":0.135417848084521,"d":"0.14"},{"v":0.919478193142111,"d":"0.92"},"up","no"]
["MSTRG.1127","ARHGAP30","ENST00000490279;ENST00000368013;MSTRG.1127.1;ENST00000368018;ENST00000368015;ENST00000471492;ENST00000461003;ENST00000368016","GO:0043231(intracellular membrane-bounded organelle);GO:0007165(signal transduction);GO:0043547(positive regulation of GTPase activity);GO:0031410(cytoplasmic vesicle);GO:0005096(GTPase activator activity);GO:0005829(cytosol);GO:0051056(regulation of small GTPase mediated signal transduction);GO:0007264(small GTPase mediated signal transduction);GO:0007264(small GTPase mediated signal transduction)","NA","NA","NA","Rho GTPase activating protein 30 [Source:HGNC Symbol;Acc:HGNC:27414]",{"v":27.2438330226869,"d":"27.24"},{"v":54.9299366533833,"d":"54.93"},{"v":0.495974229764725,"d":"0.50"},{"v":-1.01166293305847,"d":"-1.01"},{"v":0.135443165753484,"d":"0.14"},{"v":0.919478193142111,"d":"0.92"},"down","no"]
["ENSG00000198121","LPAR1","ENST00000374431;ENST00000374430;ENST00000541779;ENST00000441240","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0004930(G-protein coupled receptor activity);GO:0007186(G-protein coupled receptor signaling pathway);GO:0005886(plasma membrane);GO:0004871(signal transducer activity);GO:0007165(signal transduction);GO:0070915(lysophosphatidic acid receptor activity);GO:0008289(lipid binding);GO:0005887(integral component of plasma membrane);GO:0005515(protein binding);GO:0005768(endosome);GO:0043123(positive regulation of I-kappaB kinase/NF-kappaB signaling);GO:0008360(regulation of cell shape);GO:0009986(cell surface);GO:0007193(adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway);GO:0060326(cell chemotaxis);GO:0051496(positive regulation of stress fiber assembly);GO:0030139(endocytic vesicle);GO:0043410(positive regulation of MAPK cascade);GO:0010977(negative regulation of neuron projection development);GO:0007204(positive regulation of cytosolic calcium ion concentration);GO:0007202(activation of phospholipase C activity);GO:0051482(positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway);GO:0035025(positive regulation of Rho protein signal transduction);GO:0035727(lysophosphatidic acid binding);GO:0001965(G-protein alpha-subunit binding);GO:0005543(phospholipid binding);GO:0030165(PDZ domain binding);GO:0000187(activation of MAPK activity);GO:0007420(brain development);GO:0010942(positive regulation of cell death);GO:0014003(oligodendrocyte development);GO:0021549(cerebellum development);GO:0021554(optic nerve development);GO:0022008(neurogenesis);GO:0022038(corpus callosum development);GO:0030818(negative regulation of cAMP biosynthetic process);GO:0032060(bleb assembly);GO:0042552(myelination);GO:0043065(positive regulation of apoptotic process);GO:0060999(positive regulation of dendritic spine development);GO:0071453(cellular response to oxygen levels);GO:0071673(positive regulation of smooth muscle cell chemotaxis);GO:1904566(cellular response to 1-oleoyl-sn-glycerol 3-phosphate);GO:0005737(cytoplasm);GO:0043005(neuron projection);GO:0043025(neuronal cell body);GO:0043197(dendritic spine);GO:0043198(dendritic shaft);GO:0043198(dendritic shaft)","04015(Rap1 signaling pathway);04072(Phospholipase D signaling pathway);04151(PI3K-Akt signaling pathway);04080(Neuroactive ligand-receptor interaction);04540(Gap junction);05200(Pathways in cancer);05200(Pathways in cancer)","K04289","NA","lysophosphatidic acid receptor 1 [Source:HGNC Symbol;Acc:HGNC:3166]",{"v":0.902120290694879,"d":"0.90"},{"v":0.445562633325319,"d":"0.45"},{"v":2.02467671932492,"d":"2.02"},{"v":1.01769157088145,"d":"1.02"},{"v":0.135496150062495,"d":"0.14"},{"v":0.919478193142111,"d":"0.92"},"up","no"]
["ENSG00000091436","MAP3K20","ENST00000338983;ENST00000375213;ENST00000480606;ENST00000468408;ENST00000476618;ENST00000539448;ENST00000422149","GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0005829(cytosol);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0005515(protein binding);GO:0007049(cell cycle);GO:0000287(magnesium ion binding);GO:0030154(cell differentiation);GO:0004709(MAP kinase kinase kinase activity);GO:0000186(activation of MAPKK activity);GO:0008283(cell proliferation);GO:0007050(cell cycle arrest);GO:0043065(positive regulation of apoptotic process);GO:0008219(cell death);GO:0035556(intracellular signal transduction);GO:0000077(DNA damage checkpoint);GO:0042733(embryonic digit morphogenesis);GO:0006950(response to stress);GO:0009314(response to radiation);GO:0060173(limb development);GO:0007257(activation of JUN kinase activity);GO:0000075(cell cycle checkpoint);GO:0000165(MAPK cascade);GO:0007010(cytoskeleton organization);GO:0005622(intracellular);GO:0005622(intracellular)","04010(MAPK signaling pathway);04010(MAPK signaling pathway)","K04424","EC:2.7.11.25","mitogen-activated protein kinase kinase kinase 20 [Source:HGNC Symbol;Acc:HGNC:17797]",{"v":0.669827155373578,"d":"0.67"},{"v":0.341410200739184,"d":"0.34"},{"v":1.96194241977346,"d":"1.96"},{"v":0.972282701125821,"d":"0.97"},{"v":0.135531788143767,"d":"0.14"},{"v":0.919478193142111,"d":"0.92"},"up","no"]
["ENSG00000137185","ZSCAN9","ENST00000527436;ENST00000531979;ENST00000526391;ENST00000252207;ENST00000425468","GO:0005634(nucleus);GO:0006355(regulation of transcription, DNA-templated);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0003676(nucleic acid binding);GO:0046872(metal ion binding);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0005515(protein binding)","NA","NA","NA","zinc finger and SCAN domain containing 9 [Source:HGNC Symbol;Acc:HGNC:12984]",{"v":0.331274452091768,"d":"0.33"},{"v":0.685585802968961,"d":"0.69"},{"v":0.483199113308894,"d":"0.48"},{"v":-1.04931028762925,"d":"-1.05"},{"v":0.135735363230028,"d":"0.14"},{"v":0.919787545829511,"d":"0.92"},"down","no"]
["MSTRG.10669","RAF1","MSTRG.10669.2;ENST00000251849;ENST00000423275;ENST00000465826;ENST00000471449;ENST00000494557;ENST00000460610;ENST00000416093;ENST00000475353;ENST00000492690;ENST00000442415;ENST00000432427;ENST00000491290","GO:0008285(negative regulation of cell proliferation);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016607(nuclear speck);GO:0016020(membrane);GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0035556(intracellular signal transduction);GO:0007165(signal transduction);GO:0005829(cytosol);GO:0005739(mitochondrion);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0005057(signal transducer activity, downstream of receptor);GO:0000186(activation of MAPKK activity);GO:0042802(identical protein binding);GO:0070374(positive regulation of ERK1 and ERK2 cascade);GO:0033138(positive regulation of peptidyl-serine phosphorylation);GO:0034220(ion transmembrane transport);GO:0000165(MAPK cascade);GO:0002223(stimulatory C-type lectin receptor signaling pathway);GO:0004709(MAP kinase kinase kinase activity);GO:0017016(Ras GTPase binding);GO:0031434(mitogen-activated protein kinase kinase binding);GO:0046982(protein heterodimerization activity);GO:0001666(response to hypoxia);GO:0001678(cellular glucose homeostasis);GO:0001934(positive regulation of protein phosphorylation);GO:0007507(heart development);GO:0030154(cell differentiation);GO:0030878(thyroid gland development);GO:0035019(somatic stem cell population maintenance);GO:0035773(insulin secretion involved in cellular response to glucose stimulus);GO:0035994(response to muscle stretch);GO:0045104(intermediate filament cytoskeleton organization);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0048011(neurotrophin TRK receptor signaling pathway);GO:0048538(thymus development);GO:0060324(face development);GO:0071550(death-inducing signaling complex assembly);GO:1902042(negative regulation of extrinsic apoptotic signaling pathway via death domain receptors);GO:0031143(pseudopodium);GO:0042981(regulation of apoptotic process);GO:0043066(negative regulation of apoptotic process);GO:0019899(enzyme binding);GO:0006915(apoptotic process);GO:0007275(multicellular organism development);GO:0030168(platelet activation);GO:0005794(Golgi apparatus);GO:0008283(cell proliferation);GO:0031333(negative regulation of protein complex assembly);GO:0043154(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process);GO:0042060(wound healing);GO:2000145(regulation of cell motility);GO:0045595(regulation of cell differentiation);GO:0005741(mitochondrial outer membrane);GO:0007190(activation of adenylate cyclase activity);GO:0009968(negative regulation of signal transduction);GO:0035023(regulation of Rho protein signal transduction);GO:0005622(intracellular);GO:0005622(intracellular)","04014(Ras signaling pathway);04015(Rap1 signaling pathway);04010(MAPK signaling pathway);04012(ErbB signaling pathway);04370(VEGF signaling pathway);04371(Apelin signaling pathway);04630(Jak-STAT signaling pathway);04068(FoxO signaling pathway);04072(Phospholipase D signaling pathway);04071(Sphingolipid signaling pathway);04024(cAMP signaling pathway);04022(cGMP - PKG signaling pathway);04151(PI3K-Akt signaling pathway);04150(mTOR signaling pathway);04140(Autophagy - animal);04210(Apoptosis);04218(Cellular senescence);04510(Focal adhesion);04540(Gap junction);04550(Signaling pathways regulating pluripotency of stem cells);04810(Regulation of actin cytoskeleton);04650(Natural killer cell mediated cytotoxicity);04660(T cell receptor signaling pathway);04662(B cell receptor signaling pathway);04664(Fc epsilon RI signaling pathway);04666(Fc gamma R-mediated phagocytosis);04062(Chemokine signaling pathway);04910(Insulin signaling pathway);04912(GnRH signaling pathway);04915(Estrogen signaling pathway);04914(Progesterone-mediated oocyte maturation);04917(Prolactin signaling pathway);04921(Oxytocin signaling pathway);04926(Relaxin signaling pathway);04919(Thyroid hormone signaling pathway);04916(Melanogenesis);04270(Vascular smooth muscle contraction);04726(Serotonergic synapse);04720(Long-term potentiation);04730(Long-term depression);04722(Neurotrophin signaling pathway);04360(Axon guidance);05200(Pathways in cancer);05230(Central carbon metabolism in cancer);05231(Choline metabolism in cancer);05206(MicroRNAs in cancer);05205(Proteoglycans in cancer);05210(Colorectal cancer);05212(Pancreatic cancer);05225(Hepatocellular carcinoma);05226(Gastric cancer);05214(Glioma);05221(Acute myeloid leukemia);05220(Chronic myeloid leukemia);05218(Melanoma);05211(Renal cell carcinoma);05219(Bladder cancer);05215(Prostate cancer);05213(Endometrial cancer);05224(Breast cancer);05223(Non-small cell lung cancer);05034(Alcoholism);05152(Tuberculosis);05164(Influenza A);05161(Hepatitis B);05160(Hepatitis C);05167(Kaposi's sarcoma-associated herpesvirus infection);05165(Human papillomavirus infection);01521(EGFR tyrosine kinase inhibitor resistance);01522(Endocrine resistance);01522(Endocrine resistance)","K04366","EC:2.7.11.1","Raf-1 proto-oncogene, serine/threonine kinase [Source:HGNC Symbol;Acc:HGNC:9829]",{"v":8.78236667274117,"d":"8.78"},{"v":17.704174115713,"d":"17.70"},{"v":0.496061923890962,"d":"0.50"},{"v":-1.01140787001283,"d":"-1.01"},{"v":0.135776865294102,"d":"0.14"},{"v":0.919787545829511,"d":"0.92"},"down","no"]
["ENSG00000063180","CA11","ENST00000084798;ENST00000594088;ENST00000599267","GO:0005576(extracellular region);GO:0016323(basolateral plasma membrane);GO:0016323(basolateral plasma membrane)","NA","NA","NA","carbonic anhydrase 11 [Source:HGNC Symbol;Acc:HGNC:1370]",{"v":2.21830781590361,"d":"2.22"},{"v":1.12792547855422,"d":"1.13"},{"v":1.96671487441444,"d":"1.97"},{"v":0.975787817258196,"d":"0.98"},{"v":0.135806531845613,"d":"0.14"},{"v":0.919787545829511,"d":"0.92"},"up","no"]
["MSTRG.12715","U91328.2","ENST00000606723","NA","NA","NA","NA",null,{"v":0.587701,"d":"0.59"},{"v":0.291713,"d":"0.29"},{"v":2.01465481483513,"d":"2.01"},{"v":1.0105326727057,"d":"1.01"},{"v":0.135970726504136,"d":"0.14"},{"v":0.919864881215058,"d":"0.92"},"up","no"]
["ENSG00000188389","PDCD1","ENST00000334409;ENST00000343705","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005515(protein binding);GO:0006915(apoptotic process);GO:0002376(immune system process);GO:0007165(signal transduction);GO:0005886(plasma membrane);GO:0002644(negative regulation of tolerance induction);GO:0043065(positive regulation of apoptotic process);GO:0043066(negative regulation of apoptotic process);GO:0009897(external side of plasma membrane);GO:0070234(positive regulation of T cell apoptotic process);GO:0004871(signal transducer activity);GO:0007275(multicellular organism development);GO:0031295(T cell costimulation);GO:0006959(humoral immune response);GO:0006959(humoral immune response)","04514(Cell adhesion molecules (CAMs));04660(T cell receptor signaling pathway);04660(T cell receptor signaling pathway)","K06744","NA","programmed cell death 1 [Source:HGNC Symbol;Acc:HGNC:8760]",{"v":1.148319,"d":"1.15"},{"v":0.56832,"d":"0.57"},{"v":2.02055004222973,"d":"2.02"},{"v":1.01474808266843,"d":"1.01"},{"v":0.135970726504136,"d":"0.14"},{"v":0.919864881215058,"d":"0.92"},"up","no"]
["ENSG00000137757","CASP5","ENST00000444749;ENST00000393141;ENST00000531367;ENST00000260315;ENST00000418434","GO:0008234(cysteine-type peptidase activity);GO:0006508(proteolysis);GO:0004197(cysteine-type endopeptidase activity);GO:0016787(hydrolase activity);GO:0042981(regulation of apoptotic process);GO:0008233(peptidase activity);GO:0006915(apoptotic process);GO:0021762(substantia nigra development);GO:0071260(cellular response to mechanical stimulus);GO:0050727(regulation of inflammatory response);GO:0097153(cysteine-type endopeptidase activity involved in apoptotic process);GO:0072558(NLRP1 inflammasome complex);GO:0097110(scaffold protein binding);GO:0035234(ectopic germ cell programmed cell death);GO:0050718(positive regulation of interleukin-1 beta secretion);GO:0070269(pyroptosis);GO:0043005(neuron projection);GO:0043025(neuronal cell body);GO:0043234(protein complex);GO:0043234(protein complex)","04621(NOD-like receptor signaling pathway);04621(NOD-like receptor signaling pathway)","K04395","EC:3.4.22.58","caspase 5 [Source:HGNC Symbol;Acc:HGNC:1506]",{"v":1.37911915263819,"d":"1.38"},{"v":2.82128463567839,"d":"2.82"},{"v":0.488826662576913,"d":"0.49"},{"v":-1.03260511718075,"d":"-1.03"},{"v":0.136075514319849,"d":"0.14"},{"v":0.9199742530005,"d":"0.92"},"down","no"]
["MSTRG.14805","TMEM2","ENST00000377066;ENST00000377044;ENST00000537329;ENST00000538669;ENST00000474495;ENST00000543165;ENST00000546219;ENST00000396272;ENST00000377057;ENST00000377043","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016787(hydrolase activity);GO:0005886(plasma membrane);GO:0008152(metabolic process);GO:0016798(hydrolase activity, acting on glycosyl bonds);GO:0004415(hyalurononglucosaminidase activity);GO:0007275(multicellular organism development);GO:0005509(calcium ion binding);GO:0005887(integral component of plasma membrane);GO:0045296(cadherin binding);GO:0070062(extracellular exosome);GO:0001525(angiogenesis);GO:0030214(hyaluronan catabolic process);GO:1903670(regulation of sprouting angiogenesis);GO:1903670(regulation of sprouting angiogenesis)","NA","NA","NA","transmembrane protein 2 [Source:HGNC Symbol;Acc:HGNC:11869]",{"v":3.36528447064935,"d":"3.37"},{"v":6.78755385745455,"d":"6.79"},{"v":0.495802249429427,"d":"0.50"},{"v":-1.01216327801433,"d":"-1.01"},{"v":0.136193400943493,"d":"0.14"},{"v":0.9199742530005,"d":"0.92"},"down","no"]
["ENSG00000246223","LINC01550","ENST00000502187;ENST00000554822;ENST00000512901;ENST00000499006;ENST00000556138;ENST00000556462","NA","NA","NA","NA","long intergenic non-protein coding RNA 1550 [Source:HGNC Symbol;Acc:HGNC:20111]",{"v":1.07615898666667,"d":"1.08"},{"v":0.545892992649573,"d":"0.55"},{"v":1.97137351304579,"d":"1.97"},{"v":0.979201147445151,"d":"0.98"},{"v":0.136216084794875,"d":"0.14"},{"v":0.9199742530005,"d":"0.92"},"up","no"]
["MSTRG.8360","SIGLEC7","ENST00000317643;ENST00000601682;ENST00000599250;ENST00000536156;ENST00000305628","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0030246(carbohydrate binding);GO:0007155(cell adhesion);GO:0050776(regulation of immune response);GO:0005886(plasma membrane);GO:0005887(integral component of plasma membrane);GO:0004872(receptor activity);GO:0004872(receptor activity)","NA","NA","NA","sialic acid binding Ig like lectin 7 [Source:HGNC Symbol;Acc:HGNC:10876]",{"v":5.88296657023984,"d":"5.88"},{"v":11.8926075477239,"d":"11.89"},{"v":0.494674237473326,"d":"0.49"},{"v":-1.01544932867826,"d":"-1.02"},{"v":0.136352937867983,"d":"0.14"},{"v":0.920382330608888,"d":"0.92"},"down","no"]
["ENSG00000162927","PUS10","ENST00000602599;ENST00000398658;ENST00000316752;ENST00000421319;ENST00000430495","GO:0003723(RNA binding);GO:0016853(isomerase activity);GO:0008033(tRNA processing);GO:0009982(pseudouridine synthase activity);GO:0001522(pseudouridine synthesis);GO:0009451(RNA modification);GO:0031119(tRNA pseudouridine synthesis);GO:0031119(tRNA pseudouridine synthesis)","NA","NA","NA","pseudouridylate synthase 10 [Source:HGNC Symbol;Acc:HGNC:26505]",{"v":0.133970149130833,"d":"0.13"},{"v":0.281696645013724,"d":"0.28"},{"v":0.475583048297597,"d":"0.48"},{"v":-1.07223080237075,"d":"-1.07"},{"v":0.13679762445209,"d":"0.14"},{"v":0.921022413786574,"d":"0.92"},"down","no"]
["MSTRG.2528","FAU;SYVN1","ENST00000531743;ENST00000529639;ENST00000449943;ENST00000527765;ENST00000529259;ENST00000530451;ENST00000526060;ENST00000525297;ENST00000531018;ENST00000533685;MSTRG.2528.12;ENST00000279259;ENST00000434372;ENST00000377190;ENST00000529207;ENST00000294256;ENST00000527548;ENST00000526555;ENST00000531357;ENST00000525874","GO:0003723(RNA binding);GO:0006412(translation);GO:0030529(intracellular ribonucleoprotein complex);GO:0005622(intracellular);GO:0003735(structural constituent of ribosome);GO:0005840(ribosome);GO:0022627(cytosolic small ribosomal subunit);GO:0005615(extracellular space);GO:0008150(biological_process);GO:0005575(cellular_component);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0002227(innate immune response in mucosa);GO:0019731(antibacterial humoral response);GO:0050830(defense response to Gram-positive bacterium);GO:0061844(antimicrobial humoral immune response mediated by antimicrobial peptide);GO:0006413(translational initiation);GO:0006364(rRNA processing);GO:0000184(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay);GO:0019083(viral transcription);GO:0006614(SRP-dependent cotranslational protein targeting to membrane);GO:0015935(small ribosomal subunit);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0046872(metal ion binding);GO:0005783(endoplasmic reticulum);GO:0016740(transferase activity);GO:0016567(protein ubiquitination);GO:0005789(endoplasmic reticulum membrane);GO:0005515(protein binding);GO:0061630(ubiquitin protein ligase activity);GO:0030433(ubiquitin-dependent ERAD pathway);GO:0018279(protein N-linked glycosylation via asparagine);GO:1904264(ubiquitin protein ligase activity involved in ERAD pathway);GO:0030970(retrograde protein transport, ER to cytosol);GO:0000836(Hrd1p ubiquitin ligase complex);GO:1904380(endoplasmic reticulum mannose trimming);GO:0050821(protein stabilization);GO:0036498(IRE1-mediated unfolded protein response);GO:1902236(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway);GO:0051087(chaperone binding);GO:1990381(ubiquitin-specific protease binding);GO:0036503(ERAD pathway);GO:0042787(protein ubiquitination involved in ubiquitin-dependent protein catabolic process);GO:0070936(protein K48-linked ubiquitination);GO:0051082(unfolded protein binding);GO:0030176(integral component of endoplasmic reticulum membrane);GO:0005790(smooth endoplasmic reticulum);GO:0051117(ATPase binding);GO:0036513(Derlin-1 retrotranslocation complex);GO:0030968(endoplasmic reticulum unfolded protein response);GO:0000839(Hrd1p ubiquitin ligase ERAD-L complex);GO:0044322(endoplasmic reticulum quality control compartment);GO:0044322(endoplasmic reticulum quality control compartment)","03010(Ribosome);04141(Protein processing in endoplasmic reticulum);04120(Ubiquitin mediated proteolysis);04120(Ubiquitin mediated proteolysis)","K02983;K10601","EC:2.3.2.27","FAU, ubiquitin like and ribosomal protein S30 fusion [Source:HGNC Symbol;Acc:HGNC:3597];synoviolin 1 [Source:HGNC Symbol;Acc:HGNC:20738]",{"v":25.0224336426497,"d":"25.02"},{"v":12.8986551070391,"d":"12.90"},{"v":1.93992578567314,"d":"1.94"},{"v":0.956001461335434,"d":"0.96"},{"v":0.136921314953409,"d":"0.14"},{"v":0.921022413786574,"d":"0.92"},"up","no"]
["ENSG00000127804","METTL16","ENST00000263092;ENST00000574623;ENST00000571669;ENST00000571332;ENST00000574752;ENST00000571298","GO:0003723(RNA binding);GO:0005634(nucleus);GO:0008168(methyltransferase activity);GO:0016740(transferase activity);GO:0032259(methylation);GO:0070475(rRNA base methylation);GO:0080009(mRNA methylation);GO:0035613(RNA stem-loop binding);GO:0010608(posttranscriptional regulation of gene expression);GO:0048024(regulation of mRNA splicing, via spliceosome);GO:0016422(mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity);GO:0030629(U6 snRNA 3'-end binding);GO:0052907(23S rRNA (adenine(1618)-N(6))-methyltransferase activity);GO:0120048(U6 snRNA (adenine-(43)-N(6))-methyltransferase activity);GO:0120049(snRNA (adenine-N6)-methylation);GO:0120049(snRNA (adenine-N6)-methylation)","NA","NA","NA","methyltransferase like 16 [Source:HGNC Symbol;Acc:HGNC:28484]",{"v":1.52209367953884,"d":"1.52"},{"v":0.7800085161182,"d":"0.78"},{"v":1.95138084788319,"d":"1.95"},{"v":0.964495373913899,"d":"0.96"},{"v":0.137022407918624,"d":"0.14"},{"v":0.921022413786574,"d":"0.92"},"up","no"]
["ENSG00000140691","ARMC5","ENST00000268314;ENST00000564514;ENST00000457010;ENST00000570119;ENST00000408912","GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0005925(focal adhesion);GO:0005737(cytoplasm);GO:0005737(cytoplasm)","NA","NA","NA","armadillo repeat containing 5 [Source:HGNC Symbol;Acc:HGNC:25781]",{"v":0.691647796753832,"d":"0.69"},{"v":0.350233053201082,"d":"0.35"},{"v":1.97482159502727,"d":"1.97"},{"v":0.981722326406155,"d":"0.98"},{"v":0.137041238633945,"d":"0.14"},{"v":0.921022413786574,"d":"0.92"},"up","no"]
["MSTRG.6511","FAM83G","ENST00000388995;ENST00000399096;ENST00000580115","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005515(protein binding);GO:0030509(BMP signaling pathway);GO:0030509(BMP signaling pathway)","NA","NA","NA","family with sequence similarity 83 member G [Source:HGNC Symbol;Acc:HGNC:32554]",{"v":0.707498725241239,"d":"0.71"},{"v":0.360145458100559,"d":"0.36"},{"v":1.96448048789135,"d":"1.96"},{"v":0.97414783836815,"d":"0.97"},{"v":0.137105775695834,"d":"0.14"},{"v":0.921022413786574,"d":"0.92"},"up","no"]
["ENSG00000177082","WDR73","ENST00000434634;ENST00000559015;ENST00000560182;ENST00000559126;ENST00000558608;ENST00000559452;ENST00000560835;ENST00000558019;ENST00000558487;ENST00000558521;ENST00000560088;ENST00000561447;ENST00000559178;ENST00000561434;ENST00000559224;ENST00000560966;ENST00000559994;ENST00000398528;ENST00000561329;ENST00000560252","GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005856(cytoskeleton);GO:0000922(spindle pole);GO:0005819(spindle);GO:0032154(cleavage furrow);GO:0032154(cleavage furrow)","NA","NA","NA","WD repeat domain 73 [Source:HGNC Symbol;Acc:HGNC:25928]",{"v":0.752230653126948,"d":"0.75"},{"v":0.383034654581342,"d":"0.38"},{"v":1.96387100783123,"d":"1.96"},{"v":0.973700172792266,"d":"0.97"},{"v":0.137158387942585,"d":"0.14"},{"v":0.921022413786574,"d":"0.92"},"up","no"]
["MSTRG.13585","TRGC2","MSTRG.13585.1","NA","NA","NA","NA",null,{"v":7.043883,"d":"7.04"},{"v":3.497316,"d":"3.50"},{"v":2.01408251356183,"d":"2.01"},{"v":1.01012278933673,"d":"1.01"},{"v":0.137208321328118,"d":"0.14"},{"v":0.921022413786574,"d":"0.92"},"up","no"]
["MSTRG.9496","COPS7B","ENST00000350033;ENST00000479430;ENST00000461350;ENST00000409091;ENST00000492423;ENST00000432387;ENST00000410024;ENST00000413197;ENST00000436564;ENST00000449174;ENST00000412922;ENST00000620578;ENST00000474042;ENST00000488111;ENST00000410017","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005654(nucleoplasm);GO:0005515(protein binding);GO:0008180(COP9 signalosome);GO:0005829(cytosol);GO:0043687(post-translational protein modification);GO:0000338(protein deneddylation);GO:0006283(transcription-coupled nucleotide-excision repair);GO:0000715(nucleotide-excision repair, DNA damage recognition);GO:0000715(nucleotide-excision repair, DNA damage recognition)","NA","NA","NA","COP9 signalosome subunit 7B [Source:HGNC Symbol;Acc:HGNC:16760]",{"v":1.8903517992087,"d":"1.89"},{"v":0.969848718760303,"d":"0.97"},{"v":1.94912027272152,"d":"1.95"},{"v":0.962823116509222,"d":"0.96"},{"v":0.137216131350863,"d":"0.14"},{"v":0.921022413786574,"d":"0.92"},"up","no"]
["MSTRG.8080","PSENEN;LIN37","ENST00000587708;ENST00000301159;ENST00000590890;ENST00000591076;ENST00000587751;ENST00000595455;ENST00000587108;ENST00000591949;ENST00000592871;ENST00000222266;ENST00000590706","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005794(Golgi apparatus);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0007219(Notch signaling pathway);GO:0032580(Golgi cisterna membrane);GO:0048013(ephrin receptor signaling pathway);GO:0007220(Notch receptor processing);GO:0043065(positive regulation of apoptotic process);GO:0005887(integral component of plasma membrane);GO:0042982(amyloid precursor protein metabolic process);GO:0031293(membrane protein intracellular domain proteolysis);GO:0070765(gamma-secretase complex);GO:0006509(membrane protein ectodomain proteolysis);GO:0016485(protein processing);GO:0034205(amyloid-beta formation);GO:0042987(amyloid precursor protein catabolic process);GO:0043085(positive regulation of catalytic activity);GO:0017053(transcriptional repressor complex);GO:0007049(cell cycle);GO:0005654(nucleoplasm);GO:0051726(regulation of cell cycle);GO:0051726(regulation of cell cycle)","04330(Notch signaling pathway);05010(Alzheimer's disease);04218(Cellular senescence);04218(Cellular senescence)","K06170;K21774","NA","presenilin enhancer gamma-secretase subunit [Source:HGNC Symbol;Acc:HGNC:30100];lin-37 DREAM MuvB core complex component [Source:HGNC Symbol;Acc:HGNC:33234]",{"v":1.32534321457663,"d":"1.33"},{"v":2.7023641318328,"d":"2.70"},{"v":0.490438427214379,"d":"0.49"},{"v":-1.02785607226227,"d":"-1.03"},{"v":0.137222492575018,"d":"0.14"},{"v":0.921022413786574,"d":"0.92"},"down","no"]
["ENSG00000160199","PKNOX1","ENST00000432907;ENST00000456957;ENST00000291547;ENST00000474336;ENST00000560448;ENST00000480179;ENST00000558955;ENST00000607150;ENST00000607049;ENST00000557820;ENST00000418336","GO:0005634(nucleus);GO:0006355(regulation of transcription, DNA-templated);GO:0006366(transcription from RNA polymerase II promoter);GO:0003677(DNA binding);GO:0005829(cytosol);GO:0005515(protein binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0001228(transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding);GO:0003705(transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding);GO:0043565(sequence-specific DNA binding);GO:0046982(protein heterodimerization activity);GO:0001525(angiogenesis);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0030097(hemopoiesis);GO:0030217(T cell differentiation);GO:0030218(erythrocyte differentiation);GO:0043010(camera-type eye development);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0005667(transcription factor complex);GO:0005737(cytoplasm);GO:0005737(cytoplasm)","NA","NA","NA","PBX/knotted 1 homeobox 1 [Source:HGNC Symbol;Acc:HGNC:9022]",{"v":0.756112359664086,"d":"0.76"},{"v":1.53022434299961,"d":"1.53"},{"v":0.49411863242348,"d":"0.49"},{"v":-1.01707063635324,"d":"-1.02"},{"v":0.137248498889964,"d":"0.14"},{"v":0.921022413786574,"d":"0.92"},"down","no"]
["MSTRG.9757","PKIG","ENST00000372886;ENST00000372894;ENST00000372889;ENST00000372887;ENST00000477390;ENST00000372891;ENST00000349959","GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0005515(protein binding);GO:0004860(protein kinase inhibitor activity);GO:0004862(cAMP-dependent protein kinase inhibitor activity);GO:0006469(negative regulation of protein kinase activity);GO:0071901(negative regulation of protein serine/threonine kinase activity);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:2000480(negative regulation of cAMP-dependent protein kinase activity);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0007165(signal transduction);GO:0042308(negative regulation of protein import into nucleus);GO:0042308(negative regulation of protein import into nucleus)","NA","NA","NA","cAMP-dependent protein kinase inhibitor gamma [Source:HGNC Symbol;Acc:HGNC:9019]",{"v":1.82831441666667,"d":"1.83"},{"v":0.925979825721154,"d":"0.93"},{"v":1.97446463290145,"d":"1.97"},{"v":0.981461526119529,"d":"0.98"},{"v":0.137297388752477,"d":"0.14"},{"v":0.921022413786574,"d":"0.92"},"up","no"]
["ENSG00000264522","OTUD7B","ENST00000581312;ENST00000619871","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0016787(hydrolase activity);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0008233(peptidase activity);GO:0008234(cysteine-type peptidase activity);GO:0006508(proteolysis);GO:0036459(thiol-dependent ubiquitinyl hydrolase activity);GO:0002376(immune system process);GO:0006955(immune response);GO:0002250(adaptive immune response);GO:0005829(cytosol);GO:0016579(protein deubiquitination);GO:0004843(thiol-dependent ubiquitin-specific protease activity);GO:0070536(protein K63-linked deubiquitination);GO:0071108(protein K48-linked deubiquitination);GO:0002385(mucosal immune response);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0070530(K63-linked polyubiquitin binding);GO:0035871(protein K11-linked deubiquitination);GO:0043124(negative regulation of I-kappaB kinase/NF-kappaB signaling);GO:0071947(protein deubiquitination involved in ubiquitin-dependent protein catabolic process);GO:1990380(Lys48-specific deubiquitinase activity);GO:0032717(negative regulation of interleukin-8 production);GO:1900181(negative regulation of protein localization to nucleus);GO:1900181(negative regulation of protein localization to nucleus)","NA","NA","NA","OTU deubiquitinase 7B [Source:HGNC Symbol;Acc:HGNC:16683]",{"v":0.583170415209,"d":"0.58"},{"v":0.297377288987435,"d":"0.30"},{"v":1.96104557007257,"d":"1.96"},{"v":0.971623060748746,"d":"0.97"},{"v":0.13736557508393,"d":"0.14"},{"v":0.921022413786574,"d":"0.92"},"up","no"]
["MSTRG.3810","TMEM120B","ENST00000449592;ENST00000342607;ENST00000538055","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005634(nucleus);GO:0005515(protein binding);GO:0003674(molecular_function);GO:0008150(biological_process);GO:0005575(cellular_component);GO:0045444(fat cell differentiation);GO:0051291(protein heterooligomerization);GO:0005637(nuclear inner membrane);GO:0005637(nuclear inner membrane)","NA","NA","NA","transmembrane protein 120B [Source:HGNC Symbol;Acc:HGNC:32008]",{"v":4.88081515339093,"d":"4.88"},{"v":2.51617971049828,"d":"2.52"},{"v":1.9397720810746,"d":"1.94"},{"v":0.95588714889678,"d":"0.96"},{"v":0.137524753425516,"d":"0.14"},{"v":0.921101160277146,"d":"0.92"},"up","no"]
["ENSG00000140365","COMMD4","ENST00000267935;ENST00000562789;ENST00000566843;ENST00000562310;ENST00000564068;ENST00000565834;ENST00000561662;ENST00000338995;ENST00000567720;ENST00000569245;ENST00000563220;ENST00000564815;ENST00000480484;ENST00000564587;ENST00000568877;ENST00000567023","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0005515(protein binding);GO:0005515(protein binding)","NA","NA","NA","COMM domain containing 4 [Source:HGNC Symbol;Acc:HGNC:26027]",{"v":0.767465867827113,"d":"0.77"},{"v":0.386372771205192,"d":"0.39"},{"v":1.98633528297866,"d":"1.99"},{"v":0.990109162777847,"d":"0.99"},{"v":0.137590157273406,"d":"0.14"},{"v":0.921101160277146,"d":"0.92"},"up","no"]
["ENSG00000269984","AC078795.1","ENST00000602342","NA","NA","NA","NA",null,{"v":0.872346,"d":"0.87"},{"v":0.436314,"d":"0.44"},{"v":1.9993536764807,"d":"2.00"},{"v":0.999533700782851,"d":"1.00"},{"v":0.137632413213567,"d":"0.14"},{"v":0.921101160277146,"d":"0.92"},"up","no"]
["MSTRG.4646","TCL1A","ENST00000402399;ENST00000554012;ENST00000554119;ENST00000555202;ENST00000557043;ENST00000556156;ENST00000553467","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005783(endoplasmic reticulum);GO:0005515(protein binding);GO:0042802(identical protein binding);GO:0043231(intracellular membrane-bounded organelle);GO:0019901(protein kinase binding);GO:0043539(protein serine/threonine kinase activator activity);GO:0033138(positive regulation of peptidyl-serine phosphorylation);GO:0071902(positive regulation of protein serine/threonine kinase activity);GO:0043234(protein complex);GO:0071356(cellular response to tumor necrosis factor);GO:0008284(positive regulation of cell proliferation);GO:0043066(negative regulation of apoptotic process);GO:0007275(multicellular organism development);GO:0032461(positive regulation of protein oligomerization);GO:0070207(protein homotrimerization);GO:0010918(positive regulation of mitochondrial membrane potential);GO:0010918(positive regulation of mitochondrial membrane potential)","04151(PI3K-Akt signaling pathway);04151(PI3K-Akt signaling pathway)","K10167","NA","T-cell leukemia/lymphoma 1A [Source:HGNC Symbol;Acc:HGNC:11648]",{"v":1.49537175581395,"d":"1.50"},{"v":3.03684652683363,"d":"3.04"},{"v":0.492409393296901,"d":"0.49"},{"v":-1.02206981167263,"d":"-1.02"},{"v":0.137845506932689,"d":"0.14"},{"v":0.921101160277146,"d":"0.92"},"down","no"]
["ENSG00000245849","RAD51-AS1","ENST00000499988;ENST00000533146;ENST00000526635","NA","NA","NA","NA","RAD51 antisense RNA 1 (head to head) [Source:HGNC Symbol;Acc:HGNC:48621]",{"v":2.97145162617924,"d":"2.97"},{"v":1.51101524233491,"d":"1.51"},{"v":1.96652657294679,"d":"1.97"},{"v":0.975649681017435,"d":"0.98"},{"v":0.137895813998172,"d":"0.14"},{"v":0.921101160277146,"d":"0.92"},"up","no"]
["MSTRG.10383","LIMK2","ENST00000462625;ENST00000331728;ENST00000333611;ENST00000340552;ENST00000467301;ENST00000465937;ENST00000406516;ENST00000425203;ENST00000482270","GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0004672(protein kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0042325(regulation of phosphorylation);GO:0005634(nucleus);GO:0000166(nucleotide binding);GO:0004674(protein serine/threonine kinase activity);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0005515(protein binding);GO:0035556(intracellular signal transduction);GO:0004871(signal transducer activity);GO:0046982(protein heterodimerization activity);GO:0007283(spermatogenesis);GO:0005801(cis-Golgi network);GO:0005801(cis-Golgi network)","04810(Regulation of actin cytoskeleton);04666(Fc gamma R-mediated phagocytosis);04360(Axon guidance);04360(Axon guidance)","K05744","EC:2.7.11.1","LIM domain kinase 2 [Source:HGNC Symbol;Acc:HGNC:6614]",{"v":7.86055810729335,"d":"7.86"},{"v":15.7950686588331,"d":"15.80"},{"v":0.497659002127698,"d":"0.50"},{"v":-1.0067705542926,"d":"-1.01"},{"v":0.137938415101744,"d":"0.14"},{"v":0.921101160277146,"d":"0.92"},"down","no"]
["ENSG00000127903","ZNF835","ENST00000537055;ENST00000601659","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding)","NA","NA","NA","zinc finger protein 835 [Source:HGNC Symbol;Acc:HGNC:34332]",{"v":0.523345033112583,"d":"0.52"},{"v":0.257086092715232,"d":"0.26"},{"v":2.0356800618238,"d":"2.04"},{"v":1.02551083769557,"d":"1.03"},{"v":0.13797146955557,"d":"0.14"},{"v":0.921101160277146,"d":"0.92"},"up","no"]
["ENSG00000238083","LRRC37A2","ENST00000576629;ENST00000572638","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016021(integral component of membrane)","NA","NA","NA","leucine rich repeat containing 37 member A2 [Source:HGNC Symbol;Acc:HGNC:32404]",{"v":0.663669560686797,"d":"0.66"},{"v":1.34522688765542,"d":"1.35"},{"v":0.493351394309029,"d":"0.49"},{"v":-1.0193125086444,"d":"-1.02"},{"v":0.137989245402755,"d":"0.14"},{"v":0.921101160277146,"d":"0.92"},"down","no"]
["MSTRG.6701","SLFN12L","ENST00000260908;ENST00000361112;ENST00000628453;ENST00000590802;ENST00000587436","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005524(ATP binding);GO:0005524(ATP binding)","NA","NA","NA","schlafen family member 12 like [Source:HGNC Symbol;Acc:HGNC:33920]",{"v":1.65379338453544,"d":"1.65"},{"v":0.846884087507795,"d":"0.85"},{"v":1.95279780188362,"d":"1.95"},{"v":0.965542576300231,"d":"0.97"},{"v":0.138162859679732,"d":"0.14"},{"v":0.921372585580245,"d":"0.92"},"up","no"]
["MSTRG.7896","AC022098.1","ENST00000588387;ENST00000588658;ENST00000592086","NA","NA","NA","NA",null,{"v":1.53355120590082,"d":"1.53"},{"v":0.782437064344005,"d":"0.78"},{"v":1.95996748593007,"d":"1.96"},{"v":0.970829721546335,"d":"0.97"},{"v":0.138182933861312,"d":"0.14"},{"v":0.921372585580245,"d":"0.92"},"up","no"]
["ENSG00000137720","C11orf1","ENST00000260276;ENST00000529270;ENST00000530799;ENST00000530214;ENST00000528125","GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0003674(molecular_function);GO:0008150(biological_process);GO:0008150(biological_process)","NA","NA","NA","chromosome 11 open reading frame 1 [Source:HGNC Symbol;Acc:HGNC:1163]",{"v":1.26221148107544,"d":"1.26"},{"v":0.642141967632472,"d":"0.64"},{"v":1.96562683128953,"d":"1.97"},{"v":0.974989456089144,"d":"0.97"},{"v":0.138268623931934,"d":"0.14"},{"v":0.921433740668706,"d":"0.92"},"up","no"]
["ENSG00000075702","WDR62","ENST00000587391;ENST00000378860;ENST00000401500;ENST00000589953","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0007399(nervous system development);GO:0000922(spindle pole);GO:0005813(centrosome);GO:0005815(microtubule organizing center);GO:0003723(RNA binding);GO:0005814(centriole);GO:0021987(cerebral cortex development);GO:0005682(U5 snRNP);GO:0007099(centriole replication);GO:0007052(mitotic spindle organization);GO:0008380(RNA splicing);GO:0022008(neurogenesis);GO:0071011(precatalytic spliceosome);GO:0071013(catalytic step 2 spliceosome);GO:0071013(catalytic step 2 spliceosome)","NA","NA","NA","WD repeat domain 62 [Source:HGNC Symbol;Acc:HGNC:24502]",{"v":0.173769393452685,"d":"0.17"},{"v":0.0843344070588235,"d":"0.08"},{"v":2.06048040785394,"d":"2.06"},{"v":1.04298074577015,"d":"1.04"},{"v":0.138530466970915,"d":"0.14"},{"v":0.922668077026413,"d":"0.92"},"up","no"]
["MSTRG.1890","RRP12","ENST00000479481;ENST00000465394;ENST00000479317;ENST00000487612;ENST00000536831;ENST00000619048;ENST00000618765;ENST00000370992;ENST00000621606;ENST00000622320;ENST00000414986;ENST00000439965","GO:0003723(RNA binding);GO:0005634(nucleus);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005730(nucleolus);GO:0031965(nuclear membrane);GO:0031965(nuclear membrane)","NA","NA","NA","ribosomal RNA processing 12 homolog [Source:HGNC Symbol;Acc:HGNC:29100]",{"v":2.37018943182085,"d":"2.37"},{"v":4.75544959737367,"d":"4.76"},{"v":0.498415424932661,"d":"0.50"},{"v":-1.00457937738921,"d":"-1.00"},{"v":0.138731974962849,"d":"0.14"},{"v":0.923390398140491,"d":"0.92"},"down","no"]
["ENSG00000196730","DAPK1","ENST00000408954;ENST00000469067;ENST00000472344;ENST00000497743;ENST00000491893;ENST00000466188;ENST00000470267;ENST00000472284;ENST00000475804;ENST00000622514;ENST00000495182;ENST00000495281;ENST00000496522;ENST00000468482;ENST00000469640;ENST00000463069;ENST00000358077","GO:0005737(cytoplasm);GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0007165(signal transduction);GO:0005525(GTP binding);GO:0005886(plasma membrane);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0006915(apoptotic process);GO:0042802(identical protein binding);GO:0005516(calmodulin binding);GO:0006417(regulation of translation);GO:0071346(cellular response to interferon-gamma);GO:0017148(negative regulation of translation);GO:0042981(regulation of apoptotic process);GO:0097190(apoptotic signaling pathway);GO:0046777(protein autophosphorylation);GO:0010506(regulation of autophagy);GO:0035556(intracellular signal transduction);GO:0043280(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process);GO:0015629(actin cytoskeleton);GO:0017075(syntaxin-1 binding);GO:2000310(regulation of NMDA receptor activity);GO:0004683(calmodulin-dependent protein kinase activity);GO:0010508(positive regulation of autophagy);GO:0071447(cellular response to hydroperoxide);GO:0008625(extrinsic apoptotic signaling pathway via death domain receptors);GO:0043066(negative regulation of apoptotic process);GO:1902042(negative regulation of extrinsic apoptotic signaling pathway via death domain receptors);GO:1902042(negative regulation of extrinsic apoptotic signaling pathway via death domain receptors)","04140(Autophagy - animal);05200(Pathways in cancer);05219(Bladder cancer);05219(Bladder cancer)","K08803","EC:2.7.11.1","death associated protein kinase 1 [Source:HGNC Symbol;Acc:HGNC:2674]",{"v":1.42947323329965,"d":"1.43"},{"v":2.8727512639497,"d":"2.87"},{"v":0.497597286349912,"d":"0.50"},{"v":-1.00694947714433,"d":"-1.01"},{"v":0.13879227874392,"d":"0.14"},{"v":0.923390398140491,"d":"0.92"},"down","no"]
["ENSG00000110841","PPFIBP1","ENST00000318304;ENST00000535575;ENST00000228425;ENST00000619325;ENST00000545334","GO:0005925(focal adhesion);GO:0005829(cytosol);GO:0045296(cadherin binding);GO:0005886(plasma membrane);GO:0007155(cell adhesion);GO:0007155(cell adhesion)","NA","NA","NA","PPFIA binding protein 1 [Source:HGNC Symbol;Acc:HGNC:9249]",{"v":0.134823046963216,"d":"0.13"},{"v":0.0674796792985458,"d":"0.07"},{"v":1.99797996025926,"d":"2.00"},{"v":0.998542112970382,"d":"1.00"},{"v":0.139033864157089,"d":"0.14"},{"v":0.923707239044626,"d":"0.92"},"up","no"]
["MSTRG.14335",null,"MSTRG.14335.1","NA","NA","NA","NA",null,{"v":5.431704,"d":"5.43"},{"v":2.77397,"d":"2.77"},{"v":1.95809760019034,"d":"1.96"},{"v":0.969452676995392,"d":"0.97"},{"v":0.13904543694396,"d":"0.14"},{"v":0.923707239044626,"d":"0.92"},"up","no"]
["ENSG00000135960","EDAR","ENST00000258443;ENST00000376651;ENST00000409271","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0006915(apoptotic process);GO:0007275(multicellular organism development);GO:0030154(cell differentiation);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0033209(tumor necrosis factor-mediated signaling pathway);GO:0004888(transmembrane signaling receptor activity);GO:0004872(receptor activity);GO:0046330(positive regulation of JNK cascade);GO:0043123(positive regulation of I-kappaB kinase/NF-kappaB signaling);GO:0008544(epidermis development);GO:0001942(hair follicle development);GO:0010628(positive regulation of gene expression);GO:0042346(positive regulation of NF-kappaB import into nucleus);GO:0042475(odontogenesis of dentin-containing tooth);GO:0043473(pigmentation);GO:0060662(salivary gland cavitation);GO:0045177(apical part of cell);GO:0045177(apical part of cell)","04060(Cytokine-cytokine receptor interaction);04060(Cytokine-cytokine receptor interaction)","K05162","NA","ectodysplasin A receptor [Source:HGNC Symbol;Acc:HGNC:2895]",{"v":1.31042181156801,"d":"1.31"},{"v":0.669330500225938,"d":"0.67"},{"v":1.95780979818739,"d":"1.96"},{"v":0.969240613490861,"d":"0.97"},{"v":0.139124550274923,"d":"0.14"},{"v":0.923707239044626,"d":"0.92"},"up","no"]
["MSTRG.14707","SMIM27","ENST00000453396;ENST00000635960;ENST00000451672;ENST00000425533","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016021(integral component of membrane)","NA","NA","NA","small integral membrane protein 27 [Source:HGNC Symbol;Acc:HGNC:31420]",{"v":2.2649207727021,"d":"2.26"},{"v":4.54934907419712,"d":"4.55"},{"v":0.497856008796559,"d":"0.50"},{"v":-1.00619955225891,"d":"-1.01"},{"v":0.139152479283728,"d":"0.14"},{"v":0.923707239044626,"d":"0.92"},"down","no"]
["MSTRG.2917","CCDC84","ENST00000528088;ENST00000334418;ENST00000527356;ENST00000524670;ENST00000526463;ENST00000534656;ENST00000532132;ENST00000583842;ENST00000533787","NA","NA","NA","NA","coiled-coil domain containing 84 [Source:HGNC Symbol;Acc:HGNC:30460]",{"v":1.51852869853085,"d":"1.52"},{"v":0.775216371988247,"d":"0.78"},{"v":1.95884497980374,"d":"1.96"},{"v":0.970003229296317,"d":"0.97"},{"v":0.139223437872944,"d":"0.14"},{"v":0.923707239044626,"d":"0.92"},"up","no"]
["MSTRG.8551","PTRHD1","ENST00000328379;ENST00000487316;ENST00000492046","GO:0016787(hydrolase activity);GO:0004045(aminoacyl-tRNA hydrolase activity);GO:0070062(extracellular exosome);GO:0070062(extracellular exosome)","NA","NA","NA","peptidyl-tRNA hydrolase domain containing 1 [Source:HGNC Symbol;Acc:HGNC:33782]",{"v":1.61168717944705,"d":"1.61"},{"v":3.28141134324465,"d":"3.28"},{"v":0.491156703887486,"d":"0.49"},{"v":-1.02574470404864,"d":"-1.03"},{"v":0.139630147277474,"d":"0.14"},{"v":0.925664569894328,"d":"0.93"},"down","no"]
["MSTRG.14587","TG","ENST00000220616;ENST00000522996;ENST00000518108;ENST00000520197;ENST00000519543","GO:0005576(extracellular region);GO:0005179(hormone activity);GO:0042446(hormone biosynthetic process);GO:0007165(signal transduction);GO:0030878(thyroid gland development);GO:0015705(iodide transport);GO:0031641(regulation of myelination);GO:0042403(thyroid hormone metabolic process);GO:0005615(extracellular space);GO:0005615(extracellular space)","04918(Thyroid hormone synthesis);05320(Autoimmune thyroid disease);05320(Autoimmune thyroid disease)","K10809","NA","thyroglobulin [Source:HGNC Symbol;Acc:HGNC:11764]",{"v":0.0644369430470715,"d":"0.06"},{"v":0.135903660618038,"d":"0.14"},{"v":0.474136919888963,"d":"0.47"},{"v":-1.0766243582945,"d":"-1.08"},{"v":0.139748089027873,"d":"0.14"},{"v":0.925664569894328,"d":"0.93"},"down","no"]
["MSTRG.768","AMPD2;GNAI3","ENST00000358729;ENST00000256578;MSTRG.768.13;ENST00000369851;ENST00000342115;ENST00000486282;ENST00000531734;ENST00000533132;ENST00000393688;ENST00000474459;ENST00000531203;ENST00000524975;ENST00000528270;ENST00000476688;ENST00000479919;ENST00000529299;ENST00000528454;ENST00000532851;ENST00000526301;ENST00000527846;ENST00000467071;ENST00000528958;ENST00000369840;ENST00000525415;ENST00000534144;ENST00000528667","GO:0003876(AMP deaminase activity);GO:0032264(IMP salvage);GO:0046872(metal ion binding);GO:0016787(hydrolase activity);GO:0019239(deaminase activity);GO:0009168(purine ribonucleoside monophosphate biosynthetic process);GO:0005515(protein binding);GO:0009117(nucleotide metabolic process);GO:0005575(cellular_component);GO:0005829(cytosol);GO:0043101(purine-containing compound salvage);GO:0006188(IMP biosynthetic process);GO:0052652(cyclic purine nucleotide metabolic process);GO:0097009(energy homeostasis);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005525(GTP binding);GO:0000166(nucleotide binding);GO:0007186(G-protein coupled receptor signaling pathway);GO:0005634(nucleus);GO:0005730(nucleolus);GO:0007165(signal transduction);GO:0003924(GTPase activity);GO:0004871(signal transducer activity);GO:0005765(lysosomal membrane);GO:0051301(cell division);GO:0005813(centrosome);GO:0005886(plasma membrane);GO:0005856(cytoskeleton);GO:0007049(cell cycle);GO:0019001(guanyl nucleotide binding);GO:0031683(G-protein beta/gamma-subunit complex binding);GO:0007188(adenylate cyclase-modulating G-protein coupled receptor signaling pathway);GO:0005815(microtubule organizing center);GO:0030496(midbody);GO:0070062(extracellular exosome);GO:0006810(transport);GO:0001664(G-protein coupled receptor binding);GO:0006457(protein folding);GO:0007193(adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway);GO:0005834(heterotrimeric G-protein complex);GO:0046039(GTP metabolic process);GO:0019003(GDP binding);GO:0007212(dopamine receptor signaling pathway);GO:0007194(negative regulation of adenylate cyclase activity);GO:0019904(protein domain specific binding);GO:0031821(G-protein coupled serotonin receptor binding);GO:0032794(GTPase activating protein binding);GO:0006906(vesicle fusion);GO:0005794(Golgi apparatus);GO:0042588(zymogen granule);GO:0045121(membrane raft);GO:0097009(energy homeostasis)","00230(Purine metabolism);04015(Rap1 signaling pathway);04371(Apelin signaling pathway);04071(Sphingolipid signaling pathway);04024(cAMP signaling pathway);04022(cGMP - PKG signaling pathway);04540(Gap junction);04611(Platelet activation);04670(Leukocyte transendothelial migration);04062(Chemokine signaling pathway);04923(Regulation of lipolysis in adipocyte);04915(Estrogen signaling pathway);04914(Progesterone-mediated oocyte maturation);04921(Oxytocin signaling pathway);04926(Relaxin signaling pathway);04916(Melanogenesis);04924(Renin secretion);04261(Adrenergic signaling in cardiomyocytes);04971(Gastric acid secretion);04724(Glutamatergic synapse);04727(GABAergic synapse);04725(Cholinergic synapse);04728(Dopaminergic synapse);04726(Serotonergic synapse);04730(Long-term depression);04723(Retrograde endocannabinoid signaling);04360(Axon guidance);04713(Circadian entrainment);05200(Pathways in cancer);05012(Parkinson's disease);05030(Cocaine addiction);05032(Morphine addiction);05034(Alcoholism);05133(Pertussis);05145(Toxoplasmosis);05142(Chagas disease (American trypanosomiasis));00230(Purine metabolism)","K01490;K04630","EC:3.5.4.6","adenosine monophosphate deaminase 2 [Source:HGNC Symbol;Acc:HGNC:469];G protein subunit alpha i3 [Source:HGNC Symbol;Acc:HGNC:4387]",{"v":2.45946950172724,"d":"2.46"},{"v":4.9241630535593,"d":"4.92"},{"v":0.499469549439367,"d":"0.50"},{"v":-1.00153136924591,"d":"-1.00"},{"v":0.139839813235168,"d":"0.14"},{"v":0.925664569894328,"d":"0.93"},"down","no"]
["ENSG00000184209","SNRNP35","ENST00000526639;ENST00000529201;ENST00000529904;ENST00000527158;ENST00000412157","GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0006397(mRNA processing);GO:0008380(RNA splicing);GO:0005634(nucleus);GO:0005730(nucleolus);GO:0005681(spliceosomal complex);GO:0005654(nucleoplasm);GO:0003729(mRNA binding);GO:0000398(mRNA splicing, via spliceosome);GO:0005689(U12-type spliceosomal complex);GO:0071011(precatalytic spliceosome);GO:0000243(commitment complex);GO:0017069(snRNA binding);GO:0017069(snRNA binding)","NA","NA","NA","small nuclear ribonucleoprotein U11/U12 subunit 35 [Source:HGNC Symbol;Acc:HGNC:30852]",{"v":0.537478929961089,"d":"0.54"},{"v":0.269873382684825,"d":"0.27"},{"v":1.9915966688304,"d":"1.99"},{"v":0.993925507448774,"d":"0.99"},{"v":0.139913965602008,"d":"0.14"},{"v":0.925664569894328,"d":"0.93"},"up","no"]
["ENSG00000176083","ZNF683","ENST00000349618;ENST00000451801;ENST00000453132;ENST00000416125;ENST00000436292;ENST00000403843;ENST00000454975","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0002376(immune system process);GO:0045087(innate immune response);GO:0002250(adaptive immune response);GO:1990841(promoter-specific chromatin binding);GO:0032823(regulation of natural killer cell differentiation);GO:0033082(regulation of extrathymic T cell differentiation);GO:0051136(regulation of NK T cell differentiation);GO:0010468(regulation of gene expression);GO:0032826(regulation of natural killer cell differentiation involved in immune response);GO:0001779(natural killer cell differentiation);GO:0001779(natural killer cell differentiation)","NA","NA","NA","zinc finger protein 683 [Source:HGNC Symbol;Acc:HGNC:28495]",{"v":3.85086736275746,"d":"3.85"},{"v":1.97224420302648,"d":"1.97"},{"v":1.95253070428508,"d":"1.95"},{"v":0.965345235471749,"d":"0.97"},{"v":0.139950599731301,"d":"0.14"},{"v":0.925664569894328,"d":"0.93"},"up","no"]
["MSTRG.5601","NLRC3","ENST00000359128;ENST00000618137;ENST00000603055;ENST00000324659;ENST00000615877;MSTRG.5601.1","GO:0005737(cytoplasm);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0005829(cytosol);GO:0005515(protein binding);GO:0048471(perinuclear region of cytoplasm);GO:0005815(microtubule organizing center);GO:0003674(molecular_function);GO:0032088(negative regulation of NF-kappaB transcription factor activity);GO:0045824(negative regulation of innate immune response);GO:0050728(negative regulation of inflammatory response);GO:0042110(T cell activation);GO:0014067(negative regulation of phosphatidylinositol 3-kinase signaling);GO:0007249(I-kappaB kinase/NF-kappaB signaling);GO:0050680(negative regulation of epithelial cell proliferation);GO:1900016(negative regulation of cytokine production involved in inflammatory response);GO:1900226(negative regulation of NLRP3 inflammasome complex assembly);GO:1901223(negative regulation of NIK/NF-kappaB signaling);GO:0032688(negative regulation of interferon-beta production);GO:0048147(negative regulation of fibroblast proliferation);GO:0032715(negative regulation of interleukin-6 production);GO:0032720(negative regulation of tumor necrosis factor production);GO:0036312(phosphatidylinositol 3-kinase regulatory subunit binding);GO:0032687(negative regulation of interferon-alpha production);GO:0043124(negative regulation of I-kappaB kinase/NF-kappaB signaling);GO:0043124(negative regulation of I-kappaB kinase/NF-kappaB signaling)","NA","NA","NA","NLR family CARD domain containing 3 [Source:HGNC Symbol;Acc:HGNC:29889]",{"v":9.52864834006486,"d":"9.53"},{"v":4.93912156824882,"d":"4.94"},{"v":1.92921923633543,"d":"1.93"},{"v":0.948017100464041,"d":"0.95"},{"v":0.140054097104543,"d":"0.14"},{"v":0.925664569894328,"d":"0.93"},"up","no"]
["MSTRG.2314","HIPK3","ENST00000379016;ENST00000303296;ENST00000456517;ENST00000534262;ENST00000531504","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0005829(cytosol);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0016604(nuclear body);GO:0006915(apoptotic process);GO:0043066(negative regulation of apoptotic process);GO:0018107(peptidyl-threonine phosphorylation);GO:0009299(mRNA transcription);GO:0018105(peptidyl-serine phosphorylation);GO:0043508(negative regulation of JUN kinase activity);GO:0016605(PML body);GO:0016605(PML body)","04218(Cellular senescence);04218(Cellular senescence)","K08826","EC:2.7.11.1","homeodomain interacting protein kinase 3 [Source:HGNC Symbol;Acc:HGNC:4915]",{"v":13.5910958596381,"d":"13.59"},{"v":27.1746897332244,"d":"27.17"},{"v":0.50013803259808,"d":"0.50"},{"v":-0.999601777075753,"d":"-1.00"},{"v":0.140150795626735,"d":"0.14"},{"v":0.925664569894328,"d":"0.93"},"down","no"]
["MSTRG.13278","VNN1","ENST00000367928","GO:0016020(membrane);GO:0016787(hydrolase activity);GO:0005886(plasma membrane);GO:0016810(hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds);GO:0006807(nitrogen compound metabolic process);GO:0016811(hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides);GO:0031225(anchored component of membrane);GO:0005576(extracellular region);GO:0070062(extracellular exosome);GO:0006501(C-terminal protein lipidation);GO:0043312(neutrophil degranulation);GO:0045087(innate immune response);GO:0006928(movement of cell or subcellular component);GO:0035577(azurophil granule membrane);GO:0006954(inflammatory response);GO:0002544(chronic inflammatory response);GO:0016021(integral component of membrane);GO:0017159(pantetheine hydrolase activity);GO:0002526(acute inflammatory response);GO:0006979(response to oxidative stress);GO:0015939(pantothenate metabolic process);GO:0016337(single organismal cell-cell adhesion);GO:0033089(positive regulation of T cell differentiation in thymus);GO:1902176(negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway)","00770(Pantothenate and CoA biosynthesis)","K08069","EC:3.5.1.92","vanin 1 [Source:HGNC Symbol;Acc:HGNC:12705]",{"v":0.742428,"d":"0.74"},{"v":1.512105,"d":"1.51"},{"v":0.490989713015961,"d":"0.49"},{"v":-1.02623529669429,"d":"-1.03"},{"v":0.140151008869746,"d":"0.14"},{"v":0.925664569894328,"d":"0.93"},"down","no"]
["MSTRG.8371","LIM2","ENST00000221973;ENST00000596399","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005212(structural constituent of eye lens);GO:0030054(cell junction);GO:0007043(cell-cell junction assembly);GO:0002088(lens development in camera-type eye);GO:0043010(camera-type eye development);GO:0005886(plasma membrane);GO:0031982(vesicle);GO:0031982(vesicle)","NA","NA","NA","lens intrinsic membrane protein 2 [Source:HGNC Symbol;Acc:HGNC:6610]",{"v":1.41894697165992,"d":"1.42"},{"v":0.684972842105263,"d":"0.68"},{"v":2.07153756242187,"d":"2.07"},{"v":1.05070198040809,"d":"1.05"},{"v":0.140230469151523,"d":"0.14"},{"v":0.925664569894328,"d":"0.93"},"up","no"]
["MSTRG.4167","ARHGEF40","ENST00000555232;ENST00000298694;ENST00000554514;ENST00000556399;ENST00000557498;ENST00000555038","GO:0005737(cytoplasm);GO:0005089(Rho guanyl-nucleotide exchange factor activity);GO:0035023(regulation of Rho protein signal transduction);GO:0043547(positive regulation of GTPase activity);GO:0005085(guanyl-nucleotide exchange factor activity);GO:0005085(guanyl-nucleotide exchange factor activity)","NA","NA","NA","Rho guanine nucleotide exchange factor 40 [Source:HGNC Symbol;Acc:HGNC:25516]",{"v":3.58452249615338,"d":"3.58"},{"v":7.17071864843082,"d":"7.17"},{"v":0.49988329927542,"d":"0.50"},{"v":-1.00033676641565,"d":"-1.00"},{"v":0.140399216850159,"d":"0.14"},{"v":0.925664569894328,"d":"0.93"},"down","no"]
["MSTRG.8839","WDR54","ENST00000348227;ENST00000409791;ENST00000482880;ENST00000482605;ENST00000461531;ENST00000426787;ENST00000468778;ENST00000475328;ENST00000469932;ENST00000465134","NA","NA","NA","NA","WD repeat domain 54 [Source:HGNC Symbol;Acc:HGNC:25770]",{"v":1.12252892272727,"d":"1.12"},{"v":0.568196343356643,"d":"0.57"},{"v":1.97560039914352,"d":"1.98"},{"v":0.982291165306173,"d":"0.98"},{"v":0.14048979726227,"d":"0.14"},{"v":0.925664569894328,"d":"0.93"},"up","no"]
["MSTRG.1704","NCOA4","ENST00000581486;ENST00000583565;MSTRG.1704.1;ENST00000585132;ENST00000580070;ENST00000579039;MSTRG.1704.2;ENST00000585056;ENST00000578454","GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003713(transcription coactivator activity);GO:0045893(positive regulation of transcription, DNA-templated);GO:0005634(nucleus);GO:0030521(androgen receptor signaling pathway);GO:0050681(androgen receptor binding);GO:0008584(male gonad development);GO:0044754(autolysosome);GO:0006622(protein targeting to lysosome);GO:0006879(cellular iron ion homeostasis);GO:0009725(response to hormone);GO:0005739(mitochondrion);GO:0005739(mitochondrion)","04216(Ferroptosis);05200(Pathways in cancer);05216(Thyroid cancer);05216(Thyroid cancer)","K09289","NA","nuclear receptor coactivator 4 [Source:HGNC Symbol;Acc:HGNC:7671]",{"v":49.0196340317422,"d":"49.02"},{"v":97.9335471187303,"d":"97.93"},{"v":0.500539758580509,"d":"0.50"},{"v":-0.998443425968351,"d":"-1.00"},{"v":0.140519848570632,"d":"0.14"},{"v":0.925664569894328,"d":"0.93"},"down","no"]
["ENSG00000198816","ZNF358","ENST00000597229","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0035115(embryonic forelimb morphogenesis);GO:0019827(stem cell population maintenance);GO:0021915(neural tube development)","NA","NA","NA","zinc finger protein 358 [Source:HGNC Symbol;Acc:HGNC:16838]",{"v":4.19274001546641,"d":"4.19"},{"v":2.15895656162397,"d":"2.16"},{"v":1.94202147926155,"d":"1.94"},{"v":0.957559157426905,"d":"0.96"},{"v":0.140563806368936,"d":"0.14"},{"v":0.925664569894328,"d":"0.93"},"up","no"]
["MSTRG.5417","SEMA4B","ENST00000411539;ENST00000560993;ENST00000561085;ENST00000558065;ENST00000561321;ENST00000558848;ENST00000561252;ENST00000559983;ENST00000559247;ENST00000559300;ENST00000558975;ENST00000560263;ENST00000560003;ENST00000332496;ENST00000560089","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005886(plasma membrane);GO:0045202(synapse);GO:0045202(synapse)","04360(Axon guidance);04360(Axon guidance)","K06521","NA","semaphorin 4B [Source:HGNC Symbol;Acc:HGNC:10730]",{"v":3.75182250856409,"d":"3.75"},{"v":7.51303078903797,"d":"7.51"},{"v":0.499375367133895,"d":"0.50"},{"v":-1.00180343619683,"d":"-1.00"},{"v":0.140657417175445,"d":"0.14"},{"v":0.925664569894328,"d":"0.93"},"down","no"]
["MSTRG.8056","URI1","MSTRG.8056.1","NA","NA","NA","NA",null,{"v":5.702638,"d":"5.70"},{"v":2.88538,"d":"2.89"},{"v":1.97639063138997,"d":"1.98"},{"v":0.982868122161338,"d":"0.98"},{"v":0.140671496670538,"d":"0.14"},{"v":0.925664569894328,"d":"0.93"},"up","no"]
["ENSG00000160226","C21orf2","ENST00000462742;ENST00000496321;ENST00000397956;ENST00000470196;ENST00000339818;ENST00000478674;ENST00000325223","GO:0005737(cytoplasm);GO:0005739(mitochondrion);GO:0005886(plasma membrane);GO:0005856(cytoskeleton);GO:0042995(cell projection);GO:0005515(protein binding);GO:0003674(molecular_function);GO:0030030(cell projection organization);GO:0036064(ciliary basal body);GO:0007010(cytoskeleton organization);GO:0008360(regulation of cell shape);GO:0032391(photoreceptor connecting cilium);GO:0007224(smoothened signaling pathway);GO:0060271(cilium assembly);GO:0060271(cilium assembly)","NA","NA","NA","chromosome 21 open reading frame 2 [Source:HGNC Symbol;Acc:HGNC:1260]",{"v":1.29191508560119,"d":"1.29"},{"v":0.66336801665842,"d":"0.66"},{"v":1.9475088535455,"d":"1.95"},{"v":0.961629886919627,"d":"0.96"},{"v":0.140881394319356,"d":"0.14"},{"v":0.926504922777094,"d":"0.93"},"up","no"]
["MSTRG.1351","FCMR","ENST00000628511;ENST00000528654;ENST00000367091;ENST00000442471;MSTRG.1351.1;ENST00000463473;ENST00000530505;ENST00000529560;ENST00000533312;ENST00000474041;ENST00000525793","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005576(extracellular region);GO:0002376(immune system process);GO:0043066(negative regulation of apoptotic process);GO:0006968(cellular defense response);GO:0006968(cellular defense response)","NA","NA","NA","Fc fragment of IgM receptor [Source:HGNC Symbol;Acc:HGNC:14315]",{"v":82.2227505628141,"d":"82.22"},{"v":42.7078079180518,"d":"42.71"},{"v":1.92523930801094,"d":"1.93"},{"v":0.945037784520513,"d":"0.95"},{"v":0.140953082422159,"d":"0.14"},{"v":0.926504922777094,"d":"0.93"},"up","no"]
["MSTRG.4202","TRDV1","ENST00000390452","NA","NA","NA","NA","T-cell receptor delta variable 1 [Source:HGNC Symbol;Acc:HGNC:12262]",{"v":1.667915,"d":"1.67"},{"v":3.604814,"d":"3.60"},{"v":0.46269100153295,"d":"0.46"},{"v":-1.11187905340803,"d":"-1.11"},{"v":0.141144001168005,"d":"0.14"},{"v":0.926743365023046,"d":"0.93"},"down","no"]
["ENSG00000174013","FBXO45","ENST00000311630","GO:0016020(membrane);GO:0016567(protein ubiquitination);GO:0005886(plasma membrane);GO:0006974(cellular response to DNA damage stimulus);GO:0007275(multicellular organism development);GO:0030054(cell junction);GO:0045202(synapse);GO:0045211(postsynaptic membrane);GO:0007399(nervous system development);GO:0005515(protein binding);GO:0042787(protein ubiquitination involved in ubiquitin-dependent protein catabolic process);GO:0043161(proteasome-mediated ubiquitin-dependent protein catabolic process);GO:0042734(presynaptic membrane);GO:0001764(neuron migration);GO:0021799(cerebral cortex radially oriented cell migration);GO:0021800(cerebral cortex tangential migration);GO:0021957(corticospinal tract morphogenesis);GO:0021960(anterior commissure morphogenesis);GO:0060384(innervation);GO:0060386(synapse assembly involved in innervation);GO:0014069(postsynaptic density)","NA","NA","NA","F-box protein 45 [Source:HGNC Symbol;Acc:HGNC:29148]",{"v":0.704598829317269,"d":"0.70"},{"v":0.359763979250335,"d":"0.36"},{"v":1.958502990726,"d":"1.96"},{"v":0.969751331353393,"d":"0.97"},{"v":0.141184275202727,"d":"0.14"},{"v":0.926743365023046,"d":"0.93"},"up","no"]
["MSTRG.3614","CEP83","ENST00000397809;ENST00000552632;ENST00000546587;ENST00000551596;ENST00000547232;ENST00000547575;ENST00000546783","GO:0060271(cilium assembly);GO:0048278(vesicle docking);GO:0005814(centriole);GO:0051660(establishment of centrosome localization);GO:0005737(cytoplasm);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0003674(molecular_function);GO:0005829(cytosol);GO:0030030(cell projection organization);GO:0097711(ciliary basal body docking);GO:0005794(Golgi apparatus);GO:0071539(protein localization to centrosome);GO:0097539(ciliary transition fiber);GO:0097539(ciliary transition fiber)","NA","NA","NA","centrosomal protein 83 [Source:HGNC Symbol;Acc:HGNC:17966]",{"v":0.268357578916967,"d":"0.27"},{"v":0.13576465833935,"d":"0.14"},{"v":1.97663797191015,"d":"1.98"},{"v":0.98304866066897,"d":"0.98"},{"v":0.141220235410836,"d":"0.14"},{"v":0.926743365023046,"d":"0.93"},"up","no"]
["ENSG00000015568","RGPD5","ENST00000016946;ENST00000493394;ENST00000393283;ENST00000477523;ENST00000482778;ENST00000495582;ENST00000495473;ENST00000413468;ENST00000472794;ENST00000430736","GO:0005737(cytoplasm);GO:0046907(intracellular transport);GO:0000042(protein targeting to Golgi);GO:0005622(intracellular);GO:0005622(intracellular)","03013(RNA transport);03013(RNA transport)","K12172","NA","RANBP2-like and GRIP domain containing 5 [Source:HGNC Symbol;Acc:HGNC:32418]",{"v":0.408300818412698,"d":"0.41"},{"v":0.20749224366843,"d":"0.21"},{"v":1.96778834328457,"d":"1.97"},{"v":0.97657505171613,"d":"0.98"},{"v":0.141446100778079,"d":"0.14"},{"v":0.927720013926813,"d":"0.93"},"up","no"]
["MSTRG.7845","WDR83","ENST00000418543;ENST00000552700;ENST00000551329;ENST00000546754;ENST00000553179;ENST00000548381;ENST00000547481;ENST00000547255;ENST00000547797","GO:0006397(mRNA processing);GO:0008380(RNA splicing);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005515(protein binding);GO:0005681(spliceosomal complex);GO:0010008(endosome membrane);GO:0000165(MAPK cascade);GO:0000398(mRNA splicing, via spliceosome);GO:0000375(RNA splicing, via transesterification reactions);GO:0071013(catalytic step 2 spliceosome);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0016310(phosphorylation)","NA","NA","NA","WD repeat domain 83 [Source:HGNC Symbol;Acc:HGNC:32672]",{"v":1.72037719618644,"d":"1.72"},{"v":0.872722834322034,"d":"0.87"},{"v":1.97127556255921,"d":"1.97"},{"v":0.97912946331676,"d":"0.98"},{"v":0.141527553690765,"d":"0.14"},{"v":0.927748939327266,"d":"0.93"},"up","no"]
["ENSG00000156374","PCGF6","ENST00000369847;ENST00000492755","GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0005515(protein binding);GO:0045892(negative regulation of transcription, DNA-templated);GO:0031519(PcG protein complex);GO:0035102(PRC1 complex);GO:0000977(RNA polymerase II regulatory region sequence-specific DNA binding);GO:0001227(transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0000122(negative regulation of transcription from RNA polymerase II promoter)","04550(Signaling pathways regulating pluripotency of stem cells);04550(Signaling pathways regulating pluripotency of stem cells)","K11470","NA","polycomb group ring finger 6 [Source:HGNC Symbol;Acc:HGNC:21156]",{"v":1.11399140375048,"d":"1.11"},{"v":0.565985606582472,"d":"0.57"},{"v":1.96823274442785,"d":"1.97"},{"v":0.976900830117217,"d":"0.98"},{"v":0.141744830239007,"d":"0.14"},{"v":0.928188951809484,"d":"0.93"},"up","no"]
["ENSG00000185760","KCNQ5","ENST00000342056;ENST00000355635;ENST00000443915","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0055085(transmembrane transport);GO:0005216(ion channel activity);GO:0006811(ion transport);GO:0005244(voltage-gated ion channel activity);GO:0005249(voltage-gated potassium channel activity);GO:0005267(potassium channel activity);GO:0006813(potassium ion transport);GO:0034765(regulation of ion transmembrane transport);GO:0071805(potassium ion transmembrane transport);GO:0008076(voltage-gated potassium channel complex);GO:0005886(plasma membrane);GO:0005887(integral component of plasma membrane);GO:0005515(protein binding);GO:0030118(clathrin coat);GO:0030118(clathrin coat)","04725(Cholinergic synapse);04725(Cholinergic synapse)","K04930","NA","potassium voltage-gated channel subfamily Q member 5 [Source:HGNC Symbol;Acc:HGNC:6299]",{"v":0.377287928137384,"d":"0.38"},{"v":0.191926140951123,"d":"0.19"},{"v":1.96579750037003,"d":"1.97"},{"v":0.97511471523975,"d":"0.98"},{"v":0.141947969248192,"d":"0.14"},{"v":0.928188951809484,"d":"0.93"},"up","no"]
["MSTRG.15034","C9orf78","ENST00000461539;ENST00000461349;ENST00000372447;ENST00000492991;ENST00000461762;ENST00000480023;ENST00000495934","GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0005515(protein binding);GO:0005515(protein binding)","NA","NA","NA","chromosome 9 open reading frame 78 [Source:HGNC Symbol;Acc:HGNC:24932]",{"v":157.38265076819,"d":"157.38"},{"v":81.9324843783095,"d":"81.93"},{"v":1.92088219907384,"d":"1.92"},{"v":0.94176904632092,"d":"0.94"},{"v":0.142040590201733,"d":"0.14"},{"v":0.928188951809484,"d":"0.93"},"up","no"]
["MSTRG.9230","CYBRD1","ENST00000321348;ENST00000375252;ENST00000494587;ENST00000474182;ENST00000445146;ENST00000468308;ENST00000409484","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0046872(metal ion binding);GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0005515(protein binding);GO:0005886(plasma membrane);GO:0070062(extracellular exosome);GO:0000293(ferric-chelate reductase activity);GO:0010039(response to iron ion);GO:0031526(brush border membrane);GO:0005765(lysosomal membrane);GO:0006879(cellular iron ion homeostasis);GO:0016722(oxidoreductase activity, oxidizing metal ions);GO:0016722(oxidoreductase activity, oxidizing metal ions)","04978(Mineral absorption);04978(Mineral absorption)","K08370","EC:1.16.5.1","cytochrome b reductase 1 [Source:HGNC Symbol;Acc:HGNC:20797]",{"v":1.69200748261206,"d":"1.69"},{"v":3.38613695112056,"d":"3.39"},{"v":0.499686665671372,"d":"0.50"},{"v":-1.00090437516549,"d":"-1.00"},{"v":0.142072370776743,"d":"0.14"},{"v":0.928188951809484,"d":"0.93"},"down","no"]
["ENSG00000179304","FAM156B","ENST00000416841;ENST00000612188;ENST00000509613;ENST00000610609;ENST00000619346;ENST00000593751;ENST00000610405;ENST00000616419","GO:0035064(methylated histone binding);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005515(protein binding);GO:0005635(nuclear envelope);GO:0005635(nuclear envelope)","NA","NA","NA","family with sequence similarity 156 member B [Source:HGNC Symbol;Acc:HGNC:31962]",{"v":0.307575623877917,"d":"0.31"},{"v":0.638530963644524,"d":"0.64"},{"v":0.481692574659773,"d":"0.48"},{"v":-1.05381541008244,"d":"-1.05"},{"v":0.142157977282655,"d":"0.14"},{"v":0.928188951809484,"d":"0.93"},"down","no"]
["MSTRG.2242","SBF2;AC011092.1","ENST00000256190;ENST00000533128;ENST00000527019;ENST00000420722;ENST00000526353;ENST00000533661;ENST00000533770;ENST00000525697;ENST00000528478;ENST00000532095;ENST00000525040;ENST00000530741;ENST00000524961;ENST00000529587","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0043547(positive regulation of GTPase activity);GO:0005515(protein binding);GO:0019208(phosphatase regulator activity);GO:0043087(regulation of GTPase activity);GO:0005085(guanyl-nucleotide exchange factor activity);GO:0005829(cytosol);GO:0017112(Rab guanyl-nucleotide exchange factor activity);GO:0061024(membrane organization);GO:0042552(myelination);GO:0019902(phosphatase binding);GO:0035091(phosphatidylinositol binding);GO:0042803(protein homodimerization activity);GO:0051262(protein tetramerization);GO:0005774(vacuolar membrane);GO:0005774(vacuolar membrane)","NA","NA","NA","SET binding factor 2 [Source:HGNC Symbol;Acc:HGNC:2135]",{"v":0.841167558120117,"d":"0.84"},{"v":1.68423531078905,"d":"1.68"},{"v":0.499435888044668,"d":"0.50"},{"v":-1.00162860192759,"d":"-1.00"},{"v":0.142283364743061,"d":"0.14"},{"v":0.928188951809484,"d":"0.93"},"down","no"]
["MSTRG.9067","ACTR3","ENST00000478928;ENST00000263238;ENST00000535589;ENST00000443297;ENST00000484165;ENST00000489779","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0007015(actin filament organization);GO:0003779(actin binding);GO:0005856(cytoskeleton);GO:0042995(cell projection);GO:0005515(protein binding);GO:0034314(Arp2/3 complex-mediated actin nucleation);GO:0005885(Arp2/3 protein complex);GO:0005925(focal adhesion);GO:0007163(establishment or maintenance of cell polarity);GO:0008356(asymmetric cell division);GO:0016344(meiotic chromosome movement towards spindle pole);GO:0033206(meiotic cytokinesis);GO:0051321(meiotic cell cycle);GO:0051653(spindle localization);GO:0005903(brush border);GO:0005911(cell-cell junction);GO:0030027(lamellipodium);GO:0038096(Fc-gamma receptor signaling pathway involved in phagocytosis);GO:0060271(cilium assembly);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0030030(cell projection organization);GO:0061024(membrane organization);GO:0048013(ephrin receptor signaling pathway);GO:0015629(actin cytoskeleton);GO:0006928(movement of cell or subcellular component);GO:0051015(actin filament binding);GO:0005200(structural constituent of cytoskeleton);GO:0005200(structural constituent of cytoskeleton)","04530(Tight junction);04530(Tight junction)","K18584","NA","ARP3 actin related protein 3 homolog [Source:HGNC Symbol;Acc:HGNC:170]",{"v":9.50083009760146,"d":"9.50"},{"v":18.9314229716159,"d":"18.93"},{"v":0.501855043429443,"d":"0.50"},{"v":-0.994657380761158,"d":"-0.99"},{"v":0.142343178503432,"d":"0.14"},{"v":0.928188951809484,"d":"0.93"},"down","no"]
["MSTRG.9539","SRXN1;SCRT2;AL121758.1","ENST00000381962;ENST00000246104;ENST00000488788","GO:0005737(cytoplasm);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0005829(cytosol);GO:0098869(cellular oxidant detoxification);GO:0006979(response to oxidative stress);GO:0034599(cellular response to oxidative stress);GO:0016209(antioxidant activity);GO:0016667(oxidoreductase activity, acting on a sulfur group of donors);GO:0032542(sulfiredoxin activity);GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0000790(nuclear chromatin);GO:0001078(transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:1902042(negative regulation of extrinsic apoptotic signaling pathway via death domain receptors);GO:2001222(regulation of neuron migration)","NA","NA","NA","sulfiredoxin 1 [Source:HGNC Symbol;Acc:HGNC:16132];scratch family transcriptional repressor 2 [Source:HGNC Symbol;Acc:HGNC:15952]",{"v":2.92563709787903,"d":"2.93"},{"v":5.84154380361351,"d":"5.84"},{"v":0.500832861352382,"d":"0.50"},{"v":-0.99759886936852,"d":"-1.00"},{"v":0.142459951240848,"d":"0.14"},{"v":0.928188951809484,"d":"0.93"},"down","no"]
["ENSG00000147475","ERLIN2","ENST00000276461;ENST00000518526;ENST00000335171;ENST00000523887;ENST00000521993;ENST00000521644;ENST00000518586;ENST00000397228;ENST00000519638","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005783(endoplasmic reticulum);GO:0005829(cytosol);GO:0018108(peptidyl-tyrosine phosphorylation);GO:0006629(lipid metabolic process);GO:0005886(plasma membrane);GO:0005789(endoplasmic reticulum membrane);GO:0008202(steroid metabolic process);GO:0005515(protein binding);GO:0031625(ubiquitin protein ligase binding);GO:0045121(membrane raft);GO:0008203(cholesterol metabolic process);GO:0030433(ubiquitin-dependent ERAD pathway);GO:0070062(extracellular exosome);GO:0055085(transmembrane transport);GO:0043234(protein complex);GO:0004713(protein tyrosine kinase activity);GO:0032933(SREBP signaling pathway);GO:0045541(negative regulation of cholesterol biosynthetic process);GO:0045717(negative regulation of fatty acid biosynthetic process);GO:0015485(cholesterol binding);GO:0015485(cholesterol binding)","NA","NA","NA","ER lipid raft associated 2 [Source:HGNC Symbol;Acc:HGNC:1356]",{"v":0.641963396766695,"d":"0.64"},{"v":1.29364493501691,"d":"1.29"},{"v":0.496243891495856,"d":"0.50"},{"v":-1.01087875134789,"d":"-1.01"},{"v":0.142495264009711,"d":"0.14"},{"v":0.928188951809484,"d":"0.93"},"down","no"]
["MSTRG.10528","AL021453.1","ENST00000333487","NA","NA","NA","NA",null,{"v":0.737773,"d":"0.74"},{"v":0.370711,"d":"0.37"},{"v":1.99015675283442,"d":"1.99"},{"v":0.992882067769184,"d":"0.99"},{"v":0.142574697982259,"d":"0.14"},{"v":0.928188951809484,"d":"0.93"},"up","no"]
["MSTRG.12606","LINC00847","ENST00000501855;ENST00000502162;ENST00000509921;ENST00000501937","NA","NA","NA","NA","long intergenic non-protein coding RNA 847 [Source:HGNC Symbol;Acc:HGNC:45050]",{"v":0.758589770892784,"d":"0.76"},{"v":1.54754638646555,"d":"1.55"},{"v":0.490188712614509,"d":"0.49"},{"v":-1.02859083067966,"d":"-1.03"},{"v":0.142605943727759,"d":"0.14"},{"v":0.928188951809484,"d":"0.93"},"down","no"]
["MSTRG.5490","FBXL16","ENST00000397621;ENST00000562585;ENST00000562648;ENST00000562563","GO:0005829(cytosol);GO:0000209(protein polyubiquitination);GO:0043687(post-translational protein modification);GO:0004842(ubiquitin-protein transferase activity);GO:0005737(cytoplasm);GO:0005737(cytoplasm)","NA","NA","NA","F-box and leucine rich repeat protein 16 [Source:HGNC Symbol;Acc:HGNC:14150]",{"v":1.05943972750063,"d":"1.06"},{"v":0.539358050639258,"d":"0.54"},{"v":1.96426052460877,"d":"1.96"},{"v":0.973986290464493,"d":"0.97"},{"v":0.142752023303326,"d":"0.14"},{"v":0.928188951809484,"d":"0.93"},"up","no"]
["ENSG00000105507","CABP5","ENST00000293255","GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0005509(calcium ion binding);GO:0005515(protein binding);GO:0007165(signal transduction);GO:0005829(cytosol)","NA","NA","NA","calcium binding protein 5 [Source:HGNC Symbol;Acc:HGNC:13714]",{"v":1.57402276948701,"d":"1.57"},{"v":3.18032054230513,"d":"3.18"},{"v":0.494925825415743,"d":"0.49"},{"v":-1.01471577034838,"d":"-1.01"},{"v":0.142867693513877,"d":"0.14"},{"v":0.928188951809484,"d":"0.93"},"down","no"]
["ENSG00000172586","CHCHD1","ENST00000372833;ENST00000372837","GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0005739(mitochondrion);GO:0001650(fibrillar center);GO:0005761(mitochondrial ribosome);GO:0032543(mitochondrial translation);GO:0003723(RNA binding);GO:0005634(nucleus);GO:0030529(intracellular ribonucleoprotein complex);GO:0005840(ribosome);GO:0005515(protein binding);GO:0005743(mitochondrial inner membrane);GO:0070125(mitochondrial translational elongation);GO:0070126(mitochondrial translational termination);GO:0070126(mitochondrial translational termination)","NA","NA","NA","coiled-coil-helix-coiled-coil-helix domain containing 1 [Source:HGNC Symbol;Acc:HGNC:23518]",{"v":1.22658514699933,"d":"1.23"},{"v":2.50641765273095,"d":"2.51"},{"v":0.489377796099889,"d":"0.49"},{"v":-1.03097944950454,"d":"-1.03"},{"v":0.142950585060858,"d":"0.14"},{"v":0.928188951809484,"d":"0.93"},"down","no"]
["MSTRG.14077","TRBV5-4","ENST00000454561","NA","NA","NA","NA","T-cell receptor beta variable 5-4 [Source:HGNC Symbol;Acc:HGNC:12221]",{"v":2.969112,"d":"2.97"},{"v":1.483894,"d":"1.48"},{"v":2.00089224702034,"d":"2.00"},{"v":1.00064347665138,"d":"1.00"},{"v":0.143049109214919,"d":"0.14"},{"v":0.928188951809484,"d":"0.93"},"up","no"]
["ENSG00000132669","RIN2","ENST00000255006;ENST00000488077;ENST00000440354;ENST00000484638;ENST00000467569","GO:0005737(cytoplasm);GO:0007165(signal transduction);GO:0050790(regulation of catalytic activity);GO:0043547(positive regulation of GTPase activity);GO:0005096(GTPase activator activity);GO:0005575(cellular_component);GO:0005829(cytosol);GO:0006897(endocytosis);GO:0017112(Rab guanyl-nucleotide exchange factor activity);GO:0061024(membrane organization);GO:0030695(GTPase regulator activity);GO:0007264(small GTPase mediated signal transduction);GO:0007264(small GTPase mediated signal transduction)","NA","NA","NA","Ras and Rab interactor 2 [Source:HGNC Symbol;Acc:HGNC:18750]",{"v":1.15535561468435,"d":"1.16"},{"v":2.31891203027904,"d":"2.32"},{"v":0.498231756788688,"d":"0.50"},{"v":-1.00511111445391,"d":"-1.01"},{"v":0.143101738330941,"d":"0.14"},{"v":0.928188951809484,"d":"0.93"},"down","no"]
["ENSG00000180758","GPR157","ENST00000377411;ENST00000465853;ENST00000466131","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0004930(G-protein coupled receptor activity);GO:0007186(G-protein coupled receptor signaling pathway);GO:0005886(plasma membrane);GO:0042995(cell projection);GO:0004871(signal transducer activity);GO:0007165(signal transduction);GO:0004888(transmembrane signaling receptor activity);GO:0007166(cell surface receptor signaling pathway);GO:0007275(multicellular organism development);GO:0030154(cell differentiation);GO:0060170(ciliary membrane);GO:0060019(radial glial cell differentiation);GO:0051482(positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway);GO:0048512(circadian behavior);GO:0048512(circadian behavior)","NA","NA","NA","G protein-coupled receptor 157 [Source:HGNC Symbol;Acc:HGNC:23687]",{"v":0.422520328741623,"d":"0.42"},{"v":0.865767112807148,"d":"0.87"},{"v":0.488030005403706,"d":"0.49"},{"v":-1.0349582435821,"d":"-1.03"},{"v":0.143221581256971,"d":"0.14"},{"v":0.928188951809484,"d":"0.93"},"down","no"]
["MSTRG.81","PRKCZ-AS1","ENST00000333854;ENST00000444529","NA","NA","NA","NA","PRKCZ antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:40477]",{"v":0.911526026528258,"d":"0.91"},{"v":0.454055694348327,"d":"0.45"},{"v":2.0075203061521,"d":"2.01"},{"v":1.00541458073725,"d":"1.01"},{"v":0.143244137229425,"d":"0.14"},{"v":0.928188951809484,"d":"0.93"},"up","no"]
["ENSG00000175564","UCP3","ENST00000314032;ENST00000545271;ENST00000426995;ENST00000544614","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005743(mitochondrial inner membrane);GO:0005739(mitochondrion);GO:0005515(protein binding);GO:0006839(mitochondrial transport);GO:0031966(mitochondrial membrane);GO:0015992(proton transport);GO:0017077(oxidative phosphorylation uncoupler activity);GO:0000303(response to superoxide);GO:0001666(response to hypoxia);GO:0006631(fatty acid metabolic process);GO:0007568(aging);GO:0007584(response to nutrient);GO:0009409(response to cold);GO:0014823(response to activity);GO:0032868(response to insulin);GO:0032870(cellular response to hormone stimulus);GO:0048545(response to steroid hormone);GO:0051384(response to glucocorticoid);GO:0005215(transporter activity);GO:0006629(lipid metabolic process);GO:0007585(respiratory gaseous exchange);GO:1990542(mitochondrial transmembrane transport);GO:1990845(adaptive thermogenesis);GO:1990845(adaptive thermogenesis)","NA","NA","NA","uncoupling protein 3 [Source:HGNC Symbol;Acc:HGNC:12519]",{"v":0.56449872937025,"d":"0.56"},{"v":0.280152619163952,"d":"0.28"},{"v":2.014968594814,"d":"2.01"},{"v":1.01075735316556,"d":"1.01"},{"v":0.143310269031493,"d":"0.14"},{"v":0.928188951809484,"d":"0.93"},"up","no"]
["ENSG00000122884","P4HA1","ENST00000373008;ENST00000394890;ENST00000263556;ENST00000307116;ENST00000464310","GO:0016020(membrane);GO:0043231(intracellular membrane-bounded organelle);GO:0046872(metal ion binding);GO:0005783(endoplasmic reticulum);GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0005739(mitochondrion);GO:0005506(iron ion binding);GO:0016705(oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen);GO:0031418(L-ascorbic acid binding);GO:0005515(protein binding);GO:0051213(dioxygenase activity);GO:0016702(oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen);GO:0005788(endoplasmic reticulum lumen);GO:0004656(procollagen-proline 4-dioxygenase activity);GO:0005581(collagen trimer);GO:0018401(peptidyl-proline hydroxylation to 4-hydroxy-L-proline);GO:0030199(collagen fibril organization);GO:0016222(procollagen-proline 4-dioxygenase complex);GO:0016222(procollagen-proline 4-dioxygenase complex)","00330(Arginine and proline metabolism);00330(Arginine and proline metabolism)","K00472","EC:1.14.11.2","prolyl 4-hydroxylase subunit alpha 1 [Source:HGNC Symbol;Acc:HGNC:8546]",{"v":2.41456265470417,"d":"2.41"},{"v":4.84033568380213,"d":"4.84"},{"v":0.498841983787271,"d":"0.50"},{"v":-1.00334520379202,"d":"-1.00"},{"v":0.14333893727977,"d":"0.14"},{"v":0.928188951809484,"d":"0.93"},"down","no"]
["ENSG00000197632","SERPINB2","ENST00000457692;ENST00000443281;ENST00000299502","GO:0005615(extracellular space);GO:0043066(negative regulation of apoptotic process);GO:0004867(serine-type endopeptidase inhibitor activity);GO:0010951(negative regulation of endopeptidase activity);GO:0005737(cytoplasm);GO:0005576(extracellular region);GO:0005886(plasma membrane);GO:0030414(peptidase inhibitor activity);GO:0010466(negative regulation of peptidase activity);GO:0035722(interleukin-12-mediated signaling pathway);GO:0042730(fibrinolysis);GO:0042060(wound healing);GO:0042060(wound healing)","04610(Complement and coagulation cascades);04610(Complement and coagulation cascades)","K19821","NA","serpin family B member 2 [Source:HGNC Symbol;Acc:HGNC:8584]",{"v":0.275964688864629,"d":"0.28"},{"v":0.579153113173217,"d":"0.58"},{"v":0.476496944568943,"d":"0.48"},{"v":-1.06946113168471,"d":"-1.07"},{"v":0.14344487075898,"d":"0.14"},{"v":0.928188951809484,"d":"0.93"},"down","no"]
["ENSG00000164023","SGMS2","ENST00000394684;ENST00000504754;ENST00000506462;ENST00000515332","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0005794(Golgi apparatus);GO:0006629(lipid metabolic process);GO:0005886(plasma membrane);GO:0000139(Golgi membrane);GO:0002950(ceramide phosphoethanolamine synthase activity);GO:0033188(sphingomyelin synthase activity);GO:0006686(sphingomyelin biosynthetic process);GO:0046513(ceramide biosynthetic process);GO:1905373(ceramide phosphoethanolamine biosynthetic process);GO:0006665(sphingolipid metabolic process);GO:0005887(integral component of plasma membrane);GO:0030176(integral component of endoplasmic reticulum membrane);GO:0030173(integral component of Golgi membrane);GO:0030148(sphingolipid biosynthetic process);GO:0047493(ceramide cholinephosphotransferase activity);GO:0047493(ceramide cholinephosphotransferase activity)","00600(Sphingolipid metabolism);04071(Sphingolipid signaling pathway);04071(Sphingolipid signaling pathway)","K04714","EC:2.7.8.27","sphingomyelin synthase 2 [Source:HGNC Symbol;Acc:HGNC:28395]",{"v":0.713430408251473,"d":"0.71"},{"v":0.364797951669941,"d":"0.36"},{"v":1.95568644227741,"d":"1.96"},{"v":0.967675079679787,"d":"0.97"},{"v":0.143460944248068,"d":"0.14"},{"v":0.928188951809484,"d":"0.93"},"up","no"]
["MSTRG.8043","AC123912.4","ENST00000596996","NA","NA","NA","NA",null,{"v":6.256998,"d":"6.26"},{"v":3.230979,"d":"3.23"},{"v":1.93656411880114,"d":"1.94"},{"v":0.953499269166435,"d":"0.95"},{"v":0.143477341329419,"d":"0.14"},{"v":0.928188951809484,"d":"0.93"},"up","no"]
["ENSG00000162711","NLRP3","ENST00000336119;ENST00000391828;ENST00000391827;ENST00000348069;ENST00000532083;ENST00000366496;ENST00000474792;ENST00000366497","GO:0050728(negative regulation of inflammatory response);GO:0005737(cytoplasm);GO:0050713(negative regulation of interleukin-1 beta secretion);GO:0071222(cellular response to lipopolysaccharide);GO:0005634(nucleus);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0005829(cytosol);GO:0005783(endoplasmic reticulum);GO:0005515(protein binding);GO:0007165(signal transduction);GO:0005576(extracellular region);GO:0006915(apoptotic process);GO:0002376(immune system process);GO:0045087(innate immune response);GO:0006954(inflammatory response);GO:0042802(identical protein binding);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0016579(protein deubiquitination);GO:0043565(sequence-specific DNA binding);GO:0032753(positive regulation of interleukin-4 production);GO:0051092(positive regulation of NF-kappaB transcription factor activity);GO:0008134(transcription factor binding);GO:0002674(negative regulation of acute inflammatory response);GO:0072559(NLRP3 inflammasome complex);GO:0045630(positive regulation of T-helper 2 cell differentiation);GO:0061702(inflammasome complex);GO:2000553(positive regulation of T-helper 2 cell cytokine production);GO:0032088(negative regulation of NF-kappaB transcription factor activity);GO:0050718(positive regulation of interleukin-1 beta secretion);GO:0042834(peptidoglycan binding);GO:0002830(positive regulation of type 2 immune response);GO:0006952(defense response);GO:0009595(detection of biotic stimulus);GO:0042347(negative regulation of NF-kappaB import into nucleus);GO:0043280(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process);GO:0051259(protein oligomerization);GO:0006919(activation of cysteine-type endopeptidase activity involved in apoptotic process);GO:0032611(interleukin-1 beta production);GO:0032621(interleukin-18 production);GO:0032736(positive regulation of interleukin-13 production);GO:0032754(positive regulation of interleukin-5 production);GO:0044546(NLRP3 inflammasome complex assembly);GO:0050701(interleukin-1 secretion);GO:0050727(regulation of inflammatory response);GO:0051607(defense response to virus);GO:2000321(positive regulation of T-helper 17 cell differentiation);GO:2000321(positive regulation of T-helper 17 cell differentiation)","04217(Necroptosis);04621(NOD-like receptor signaling pathway);05133(Pertussis);05164(Influenza A);05164(Influenza A)","K12800","NA","NLR family pyrin domain containing 3 [Source:HGNC Symbol;Acc:HGNC:16400]",{"v":2.22306198927896,"d":"2.22"},{"v":4.43588524132857,"d":"4.44"},{"v":0.501154080490401,"d":"0.50"},{"v":-0.996673864752228,"d":"-1.00"},{"v":0.143541364837932,"d":"0.14"},{"v":0.928188951809484,"d":"0.93"},"down","no"]
["MSTRG.6327","MED11","ENST00000293777;ENST00000573708;ENST00000575284","GO:0001104(RNA polymerase II transcription cofactor activity);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0016592(mediator complex);GO:0005634(nucleus);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0005515(protein binding);GO:0061630(ubiquitin protein ligase activity);GO:0016567(protein ubiquitination);GO:0000151(ubiquitin ligase complex);GO:0000151(ubiquitin ligase complex)","NA","NA","NA","mediator complex subunit 11 [Source:HGNC Symbol;Acc:HGNC:32687]",{"v":2.49406318483412,"d":"2.49"},{"v":5.04499964725795,"d":"5.04"},{"v":0.494363401232285,"d":"0.49"},{"v":-1.01635615345558,"d":"-1.02"},{"v":0.143570365100269,"d":"0.14"},{"v":0.928188951809484,"d":"0.93"},"down","no"]
["MSTRG.8677","CALM2;STPG4","ENST00000272298;ENST00000460218;ENST00000456319;ENST00000489742;ENST00000484408;ENST00000432899;ENST00000464527;ENST00000409563;ENST00000628793;ENST00000496939;ENST00000294947;ENST00000482532;ENST00000482548","GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0005509(calcium ion binding);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0000922(spindle pole);GO:0005819(spindle);GO:0000086(G2/M transition of mitotic cell cycle);GO:0043388(positive regulation of DNA binding);GO:0008076(voltage-gated potassium channel complex);GO:0019855(calcium channel inhibitor activity);GO:0060315(negative regulation of ryanodine-sensitive calcium-release channel activity);GO:0005634(nucleus);GO:0003682(chromatin binding);GO:0044727(DNA demethylation of male pronucleus);GO:0001940(male pronucleus);GO:0001939(female pronucleus);GO:1901537(positive regulation of DNA demethylation);GO:0042585(germinal vesicle);GO:0042585(germinal vesicle)","04014(Ras signaling pathway);04015(Rap1 signaling pathway);04371(Apelin signaling pathway);04020(Calcium signaling pathway);04070(Phosphatidylinositol signaling system);04024(cAMP signaling pathway);04022(cGMP - PKG signaling pathway);04114(Oocyte meiosis);04218(Cellular senescence);04910(Insulin signaling pathway);04922(Glucagon signaling pathway);04912(GnRH signaling pathway);04915(Estrogen signaling pathway);04921(Oxytocin signaling pathway);04916(Melanogenesis);04924(Renin secretion);04925(Aldosterone synthesis and secretion);04261(Adrenergic signaling in cardiomyocytes);04270(Vascular smooth muscle contraction);04970(Salivary secretion);04971(Gastric acid secretion);04728(Dopaminergic synapse);04720(Long-term potentiation);04722(Neurotrophin signaling pathway);04744(Phototransduction);04740(Olfactory transduction);04750(Inflammatory mediator regulation of TRP channels);04713(Circadian entrainment);05200(Pathways in cancer);05214(Glioma);05010(Alzheimer's disease);05031(Amphetamine addiction);05034(Alcoholism);05418(Fluid shear stress and atherosclerosis);05133(Pertussis);05152(Tuberculosis);05167(Kaposi's sarcoma-associated herpesvirus infection);05167(Kaposi's sarcoma-associated herpesvirus infection)","K02183","NA","calmodulin 2 [Source:HGNC Symbol;Acc:HGNC:1445];sperm-tail PG-rich repeat containing 4 [Source:HGNC Symbol;Acc:HGNC:26850]",{"v":6.33318652257085,"d":"6.33"},{"v":12.5969737595142,"d":"12.60"},{"v":0.502754601500026,"d":"0.50"},{"v":-0.992073713919363,"d":"-0.99"},{"v":0.143598739181288,"d":"0.14"},{"v":0.928188951809484,"d":"0.93"},"down","no"]
["MSTRG.2103","CTSD;AC068580.4;IFITM10","ENST00000637915;ENST00000637387;ENST00000236671;ENST00000497544;ENST00000433655;ENST00000637381;ENST00000636571;ENST00000427721;ENST00000340134;ENST00000367196;ENST00000636615;ENST00000429746;ENST00000482459;ENST00000636843;ENST00000637937;ENST00000637158;ENST00000636397;ENST00000637815;ENST00000382123;ENST00000438213","GO:0005615(extracellular space);GO:0016787(hydrolase activity);GO:0005764(lysosome);GO:0005515(protein binding);GO:0008233(peptidase activity);GO:0006508(proteolysis);GO:0005576(extracellular region);GO:0042470(melanosome);GO:0004190(aspartic-type endopeptidase activity);GO:0045121(membrane raft);GO:0004252(serine-type endopeptidase activity);GO:0070062(extracellular exosome);GO:0030574(collagen catabolic process);GO:0031012(extracellular matrix);GO:0043312(neutrophil degranulation);GO:0006914(autophagy);GO:0030163(protein catabolic process);GO:0019886(antigen processing and presentation of exogenous peptide antigen via MHC class II);GO:1904813(ficolin-1-rich granule lumen);GO:0035580(specific granule lumen);GO:1904724(tertiary granule lumen);GO:0043202(lysosomal lumen);GO:0004197(cysteine-type endopeptidase activity);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0009607(response to biotic stimulus);GO:0005886(plasma membrane);GO:0004197(cysteine-type endopeptidase activity)","04071(Sphingolipid signaling pathway);04142(Lysosome);04140(Autophagy - animal);04210(Apoptosis);05152(Tuberculosis);05152(Tuberculosis)","K01379","EC:3.4.23.5","cathepsin D [Source:HGNC Symbol;Acc:HGNC:2529];interferon induced transmembrane protein 10 [Source:HGNC Symbol;Acc:HGNC:40022]",{"v":22.615168340257,"d":"22.62"},{"v":44.9354255420732,"d":"44.94"},{"v":0.503281499339143,"d":"0.50"},{"v":-0.990562529641946,"d":"-0.99"},{"v":0.143735921819778,"d":"0.14"},{"v":0.928577237421548,"d":"0.93"},"down","no"]
["ENSG00000172888","ZNF621","ENST00000310898;ENST00000462161;ENST00000403205;ENST00000431278;ENST00000492098;ENST00000339296","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0016607(nuclear speck);GO:0046872(metal ion binding);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0005622(intracellular);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding)","NA","NA","NA","zinc finger protein 621 [Source:HGNC Symbol;Acc:HGNC:24787]",{"v":0.256005531481925,"d":"0.26"},{"v":0.517632194397893,"d":"0.52"},{"v":0.494570342132041,"d":"0.49"},{"v":-1.01575236656653,"d":"-1.02"},{"v":0.144236028403537,"d":"0.14"},{"v":0.931113223469148,"d":"0.93"},"down","no"]
["MSTRG.9633","ABHD12","ENST00000339157;ENST00000465694;ENST00000376542;ENST00000576316;ENST00000481556;ENST00000461204","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016787(hydrolase activity);GO:0005886(plasma membrane);GO:0047372(acylglycerol lipase activity);GO:0052651(monoacylglycerol catabolic process);GO:0046464(acylglycerol catabolic process);GO:0004622(lysophospholipase activity);GO:0006660(phosphatidylserine catabolic process);GO:0007628(adult walking behavior);GO:0010996(response to auditory stimulus);GO:0046475(glycerophospholipid catabolic process);GO:0032281(AMPA glutamate receptor complex);GO:0032281(AMPA glutamate receptor complex)","NA","NA","NA","abhydrolase domain containing 12 [Source:HGNC Symbol;Acc:HGNC:15868]",{"v":2.16282411111111,"d":"2.16"},{"v":1.11847582093905,"d":"1.12"},{"v":1.93372451207327,"d":"1.93"},{"v":0.951382276006393,"d":"0.95"},{"v":0.144283115345742,"d":"0.14"},{"v":0.931113223469148,"d":"0.93"},"up","no"]
["ENSG00000186272","ZNF17","ENST00000307658;ENST00000602050;ENST00000601808;ENST00000599867","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0005622(intracellular);GO:0005622(intracellular)","NA","NA","NA","zinc finger protein 17 [Source:HGNC Symbol;Acc:HGNC:12958]",{"v":0.978432605263158,"d":"0.98"},{"v":0.500180919457735,"d":"0.50"},{"v":1.95615739665542,"d":"1.96"},{"v":0.968022457324143,"d":"0.97"},{"v":0.144658215521908,"d":"0.14"},{"v":0.93303386787082,"d":"0.93"},"up","no"]
["ENSG00000166707","ZCCHC18","ENST00000537356;ENST00000611638;ENST00000422784;ENST00000605784;ENST00000603049","GO:0003676(nucleic acid binding);GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0030509(BMP signaling pathway);GO:0030374(ligand-dependent nuclear receptor transcription coactivator activity);GO:0016607(nuclear speck);GO:0016607(nuclear speck)","NA","NA","NA","zinc finger CCHC-type containing 18 [Source:HGNC Symbol;Acc:HGNC:32459]",{"v":0.412862743582178,"d":"0.41"},{"v":0.208215859545589,"d":"0.21"},{"v":1.98285925233174,"d":"1.98"},{"v":0.987582275564988,"d":"0.99"},{"v":0.144784441983511,"d":"0.14"},{"v":0.933348099767364,"d":"0.93"},"up","no"]
["MSTRG.8291","SPHK2","ENST00000598088;ENST00000245222;ENST00000597434;ENST00000598574;ENST00000600537;ENST00000599029;ENST00000593308;ENST00000601712","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0043231(intracellular membrane-bounded organelle);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0005765(lysosomal membrane);GO:0008152(metabolic process);GO:0003951(NAD+ kinase activity);GO:0017050(D-erythro-sphingosine kinase activity);GO:0001568(blood vessel development);GO:0006670(sphingosine metabolic process);GO:0007420(brain development);GO:0007565(female pregnancy);GO:0008284(positive regulation of cell proliferation);GO:0005829(cytosol);GO:0046834(lipid phosphorylation);GO:0005764(lysosome);GO:0003376(sphingosine-1-phosphate signaling pathway);GO:0005515(protein binding);GO:0008283(cell proliferation);GO:0043066(negative regulation of apoptotic process);GO:0030148(sphingolipid biosynthetic process);GO:0038036(sphingosine-1-phosphate receptor activity);GO:0017016(Ras GTPase binding);GO:0046512(sphingosine biosynthetic process);GO:0008481(sphinganine kinase activity);GO:0006669(sphinganine-1-phosphate biosynthetic process);GO:0006669(sphinganine-1-phosphate biosynthetic process)","00600(Sphingolipid metabolism);04370(VEGF signaling pathway);04371(Apelin signaling pathway);04020(Calcium signaling pathway);04072(Phospholipase D signaling pathway);04071(Sphingolipid signaling pathway);04666(Fc gamma R-mediated phagocytosis);05152(Tuberculosis);05152(Tuberculosis)","K04718","EC:2.7.1.91","sphingosine kinase 2 [Source:HGNC Symbol;Acc:HGNC:18859]",{"v":0.40841693642869,"d":"0.41"},{"v":0.828513276085871,"d":"0.83"},{"v":0.49295158957279,"d":"0.49"},{"v":-1.02048212153479,"d":"-1.02"},{"v":0.1450531890377,"d":"0.15"},{"v":0.934580258101652,"d":"0.93"},"down","no"]
["MSTRG.4141","RPGRIP1","ENST00000557771;ENST00000555322;ENST00000400017;ENST00000555587;ENST00000553500;ENST00000557606;ENST00000556336;ENST00000553927","GO:0007601(visual perception);GO:0042462(eye photoreceptor cell development);GO:0032391(photoreceptor connecting cilium);GO:0042995(cell projection);GO:0005515(protein binding);GO:0050896(response to stimulus);GO:0005929(cilium);GO:0060041(retina development in camera-type eye);GO:0061351(neural precursor cell proliferation);GO:0005930(axoneme);GO:0097730(non-motile cilium);GO:0097730(non-motile cilium)","NA","NA","NA","retinitis pigmentosa GTPase regulator interacting protein 1 [Source:HGNC Symbol;Acc:HGNC:13436]",{"v":0.441740126142596,"d":"0.44"},{"v":0.888462279159049,"d":"0.89"},{"v":0.497196264269895,"d":"0.50"},{"v":-1.00811263827883,"d":"-1.01"},{"v":0.145367977103351,"d":"0.15"},{"v":0.935638610823048,"d":"0.94"},"down","no"]
["ENSG00000056736","IL17RB","ENST00000475124;ENST00000288167","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005886(plasma membrane);GO:0005576(extracellular region);GO:0019221(cytokine-mediated signaling pathway);GO:0005887(integral component of plasma membrane);GO:0001558(regulation of cell growth);GO:0006952(defense response);GO:0004896(cytokine receptor activity);GO:0097398(cellular response to interleukin-17);GO:0030368(interleukin-17 receptor activity);GO:0050729(positive regulation of inflammatory response);GO:2000664(positive regulation of interleukin-5 secretion);GO:2000667(positive regulation of interleukin-13 secretion);GO:0005737(cytoplasm);GO:0009986(cell surface);GO:0009986(cell surface)","04060(Cytokine-cytokine receptor interaction);04657(IL-17 signaling pathway);04657(IL-17 signaling pathway)","K05165","NA","interleukin 17 receptor B [Source:HGNC Symbol;Acc:HGNC:18015]",{"v":0.738145958525346,"d":"0.74"},{"v":0.374561514812377,"d":"0.37"},{"v":1.97069354254159,"d":"1.97"},{"v":0.978703444047281,"d":"0.98"},{"v":0.145372848434639,"d":"0.15"},{"v":0.935638610823048,"d":"0.94"},"up","no"]
["ENSG00000247828","TMEM161B-AS1","ENST00000504769;ENST00000506584;ENST00000496733;ENST00000512724;ENST00000501715;ENST00000507736;ENST00000510087;ENST00000504636;ENST00000513011","NA","NA","NA","NA","TMEM161B antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:43839]",{"v":0.6841990234287,"d":"0.68"},{"v":0.346682485694976,"d":"0.35"},{"v":1.97356097195716,"d":"1.97"},{"v":0.980801091098974,"d":"0.98"},{"v":0.145471314566178,"d":"0.15"},{"v":0.935772206199742,"d":"0.94"},"up","no"]
["ENSG00000137177","KIF13A","ENST00000378814;ENST00000502704;ENST00000378843;ENST00000378826;ENST00000358380;ENST00000506044;ENST00000503342;ENST00000514714;ENST00000502297;ENST00000507576;ENST00000259711;ENST00000505588","GO:0006810(transport);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0015031(protein transport);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0005794(Golgi apparatus);GO:0051301(cell division);GO:0003777(microtubule motor activity);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0007049(cell cycle);GO:0008017(microtubule binding);GO:0000139(Golgi membrane);GO:0005874(microtubule);GO:0007018(microtubule-based movement);GO:0006886(intracellular protein transport);GO:0005813(centrosome);GO:0005815(microtubule organizing center);GO:0030496(midbody);GO:0072383(plus-end-directed vesicle transport along microtubule);GO:0005768(endosome);GO:0008333(endosome to lysosome transport);GO:0030705(cytoskeleton-dependent intracellular transport);GO:0016887(ATPase activity);GO:0010008(endosome membrane);GO:0005871(kinesin complex);GO:0032438(melanosome organization);GO:0000910(cytokinesis);GO:0032588(trans-Golgi network membrane);GO:0035459(cargo loading into vesicle);GO:0043001(Golgi to plasma membrane protein transport);GO:0005622(intracellular);GO:0005623(cell);GO:0003774(motor activity);GO:0003774(motor activity)","NA","NA","NA","kinesin family member 13A [Source:HGNC Symbol;Acc:HGNC:14566]",{"v":2.01559485736114,"d":"2.02"},{"v":3.99893181080352,"d":"4.00"},{"v":0.504033315075742,"d":"0.50"},{"v":-0.98840900023737,"d":"-0.99"},{"v":0.14563914913523,"d":"0.15"},{"v":0.936351646495694,"d":"0.94"},"down","no"]
["MSTRG.3068","CD4","ENST00000011653;MSTRG.3068.4;ENST00000535466;MSTRG.3068.3;ENST00000539492;ENST00000536610;ENST00000543755;MSTRG.3068.7;ENST00000536590;ENST00000536563;MSTRG.3068.1;ENST00000437800;ENST00000538827;ENST00000544344","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0007155(cell adhesion);GO:0008270(zinc ion binding);GO:0042803(protein homodimerization activity);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0006955(immune response);GO:0015026(coreceptor activity);GO:0045121(membrane raft);GO:0002376(immune system process);GO:0002250(adaptive immune response);GO:0005789(endoplasmic reticulum membrane);GO:0019901(protein kinase binding);GO:0061024(membrane organization);GO:0050852(T cell receptor signaling pathway);GO:0016032(viral process);GO:0007165(signal transduction);GO:0019899(enzyme binding);GO:0004872(receptor activity);GO:0007166(cell surface receptor signaling pathway);GO:0030217(T cell differentiation);GO:0004888(transmembrane signaling receptor activity);GO:0007169(transmembrane receptor protein tyrosine kinase signaling pathway);GO:0045860(positive regulation of protein kinase activity);GO:0045893(positive regulation of transcription, DNA-templated);GO:0001618(virus receptor activity);GO:0031295(T cell costimulation);GO:0030665(clathrin-coated vesicle membrane);GO:0050690(regulation of defense response to virus by virus);GO:0009897(external side of plasma membrane);GO:0005887(integral component of plasma membrane);GO:0042101(T cell receptor complex);GO:0001934(positive regulation of protein phosphorylation);GO:0005201(extracellular matrix structural constituent);GO:0019865(immunoglobulin binding);GO:0042011(interleukin-16 binding);GO:0042012(interleukin-16 receptor activity);GO:0042289(MHC class II protein binding);GO:1990782(protein tyrosine kinase binding);GO:0001816(cytokine production);GO:0006948(induction by virus of host cell-cell fusion);GO:0007167(enzyme linked receptor protein signaling pathway);GO:0010524(positive regulation of calcium ion transport into cytosol);GO:0019064(fusion of virus membrane with host plasma membrane);GO:0030260(entry into host cell);GO:0032355(response to estradiol);GO:0032507(maintenance of protein location in cell);GO:0033280(response to vitamin D);GO:0033674(positive regulation of kinase activity);GO:0035397(helper T cell enhancement of adaptive immune response);GO:0035723(interleukin-15-mediated signaling pathway);GO:0042102(positive regulation of T cell proliferation);GO:0042110(T cell activation);GO:0043123(positive regulation of I-kappaB kinase/NF-kappaB signaling);GO:0043410(positive regulation of MAPK cascade);GO:0045058(T cell selection);GO:0045086(positive regulation of interleukin-2 biosynthetic process);GO:0045657(positive regulation of monocyte differentiation);GO:0046598(positive regulation of viral entry into host cell);GO:0050731(positive regulation of peptidyl-tyrosine phosphorylation);GO:0050829(defense response to Gram-negative bacterium);GO:0050850(positive regulation of calcium-mediated signaling);GO:0050863(regulation of T cell activation);GO:0050870(positive regulation of T cell activation);GO:0051924(regulation of calcium ion transport);GO:0070374(positive regulation of ERK1 and ERK2 cascade);GO:0097011(cellular response to granulocyte macrophage colony-stimulating factor stimulus);GO:0005769(early endosome);GO:0005788(endoplasmic reticulum lumen);GO:0009986(cell surface);GO:0009986(cell surface)","04514(Cell adhesion molecules (CAMs));04640(Hematopoietic cell lineage);04612(Antigen processing and presentation);04660(T cell receptor signaling pathway);04658(Th1 and Th2 cell differentiation);04659(Th17 cell differentiation);05340(Primary immunodeficiency);05340(Primary immunodeficiency)","K06454","NA","CD4 molecule [Source:HGNC Symbol;Acc:HGNC:1678]",{"v":29.3095610047983,"d":"29.31"},{"v":15.3581024207197,"d":"15.36"},{"v":1.9084103101993,"d":"1.91"},{"v":0.932371385625393,"d":"0.93"},{"v":0.146261451427817,"d":"0.15"},{"v":0.939850799409698,"d":"0.94"},"up","no"]
["ENSG00000161513","FDXR","ENST00000578473;ENST00000577509;ENST00000581219;ENST00000583881;ENST00000420580;ENST00000581530;ENST00000583917;ENST00000579482;ENST00000442102;ENST00000577932;ENST00000293195","GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0005739(mitochondrion);GO:0005759(mitochondrial matrix);GO:0015039(NADPH-adrenodoxin reductase activity);GO:0006629(lipid metabolic process);GO:0008202(steroid metabolic process);GO:0005515(protein binding);GO:0008203(cholesterol metabolic process);GO:0006091(generation of precursor metabolites and energy);GO:0006744(ubiquinone biosynthetic process);GO:0016125(sterol metabolic process);GO:0006700(C21-steroid hormone biosynthetic process);GO:0006694(steroid biosynthetic process);GO:0004324(ferredoxin-NADP+ reductase activity);GO:0070402(NADPH binding);GO:0070995(NADPH oxidation);GO:0005743(mitochondrial inner membrane);GO:0005743(mitochondrial inner membrane)","NA","NA","NA","ferredoxin reductase [Source:HGNC Symbol;Acc:HGNC:3642]",{"v":0.472280043901084,"d":"0.47"},{"v":0.232102307029731,"d":"0.23"},{"v":2.03479254448163,"d":"2.03"},{"v":1.02488171326095,"d":"1.02"},{"v":0.146343918938238,"d":"0.15"},{"v":0.93987918498894,"d":"0.94"},"up","no"]
["MSTRG.11344","FNDC3B","ENST00000415807;ENST00000421757;ENST00000483344;ENST00000416957;ENST00000476794;ENST00000478016;ENST00000490832;ENST00000423424;ENST00000469491;ENST00000494000;ENST00000443501;ENST00000336824","GO:0003723(RNA binding);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016021(integral component of membrane)","NA","NA","NA","fibronectin type III domain containing 3B [Source:HGNC Symbol;Acc:HGNC:24670]",{"v":2.19844490580256,"d":"2.20"},{"v":4.3555639720422,"d":"4.36"},{"v":0.504744028537772,"d":"0.50"},{"v":-0.986376157284856,"d":"-0.99"},{"v":0.14662516834285,"d":"0.15"},{"v":0.940427826220425,"d":"0.94"},"down","no"]
["MSTRG.2878","JAML","ENST00000292067;ENST00000526620;ENST00000356289;ENST00000529164;ENST00000534294;MSTRG.2878.4;ENST00000531536;ENST00000531530;ENST00000527877;ENST00000524477;ENST00000526595;ENST00000525565;ENST00000533261","GO:0016021(integral component of membrane);GO:0016020(membrane);GO:0050900(leukocyte migration);GO:0046629(gamma-delta T cell activation);GO:0007155(cell adhesion);GO:0042803(protein homodimerization activity);GO:0005886(plasma membrane);GO:0030054(cell junction);GO:0002376(immune system process);GO:0050776(regulation of immune response);GO:0005923(bicellular tight junction);GO:0030593(neutrophil chemotaxis);GO:0060054(positive regulation of epithelial cell proliferation involved in wound healing);GO:0005178(integrin binding);GO:0072672(neutrophil extravasation);GO:0050839(cell adhesion molecule binding);GO:0007157(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules);GO:0035696(monocyte extravasation);GO:0035696(monocyte extravasation)","NA","NA","NA","junction adhesion molecule like [Source:HGNC Symbol;Acc:HGNC:19084]",{"v":25.8390544711774,"d":"25.84"},{"v":51.089763105159,"d":"51.09"},{"v":0.50575796207926,"d":"0.51"},{"v":-0.98348096777193,"d":"-0.98"},{"v":0.146722249347498,"d":"0.15"},{"v":0.940427826220425,"d":"0.94"},"down","no"]
["ENSG00000198019","FCGR1B","ENST00000472543;ENST00000453173;ENST00000369384;ENST00000615565;ENST00000369178;ENST00000623603;ENST00000466915;ENST00000471609;ENST00000369383;ENST00000616817","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005886(plasma membrane);GO:0006955(immune response);GO:0002376(immune system process);GO:0002250(adaptive immune response);GO:0006898(receptor-mediated endocytosis);GO:0002479(antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent);GO:0060333(interferon-gamma-mediated signaling pathway);GO:0030669(clathrin-coated endocytic vesicle membrane);GO:0019864(IgG binding);GO:0031901(early endosome membrane);GO:0019763(immunoglobulin receptor activity);GO:0038093(Fc receptor signaling pathway);GO:0038093(Fc receptor signaling pathway)","NA","NA","NA","Fc fragment of IgG receptor Ib [Source:HGNC Symbol;Acc:HGNC:3614]",{"v":0.705571565178835,"d":"0.71"},{"v":1.43377676736624,"d":"1.43"},{"v":0.492106987111339,"d":"0.49"},{"v":-1.02295609437274,"d":"-1.02"},{"v":0.14675370542942,"d":"0.15"},{"v":0.940427826220425,"d":"0.94"},"down","no"]
["MSTRG.8289","PPP1R15A","ENST00000200453;ENST00000600406","GO:0016020(membrane);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005739(mitochondrion);GO:0005515(protein binding);GO:0006915(apoptotic process);GO:0005741(mitochondrial outer membrane);GO:0005829(cytosol);GO:0019901(protein kinase binding);GO:0006417(regulation of translation);GO:0005737(cytoplasm);GO:0070059(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress);GO:0005794(Golgi apparatus);GO:0007050(cell cycle arrest);GO:0034976(response to endoplasmic reticulum stress);GO:0006974(cellular response to DNA damage stimulus);GO:0008157(protein phosphatase 1 binding);GO:0019888(protein phosphatase regulator activity);GO:0019903(protein phosphatase binding);GO:0072542(protein phosphatase activator activity);GO:0010628(positive regulation of gene expression);GO:0030968(endoplasmic reticulum unfolded protein response);GO:0032058(positive regulation of translational initiation in response to stress);GO:0032515(negative regulation of phosphoprotein phosphatase activity);GO:0032516(positive regulation of phosphoprotein phosphatase activity);GO:0033138(positive regulation of peptidyl-serine phosphorylation);GO:0035308(negative regulation of protein dephosphorylation);GO:0036496(regulation of translational initiation by eIF2 alpha dephosphorylation);GO:0045943(positive regulation of transcription from RNA polymerase I promoter);GO:0060734(regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation);GO:0070262(peptidyl-serine dephosphorylation);GO:0070972(protein localization to endoplasmic reticulum);GO:1902310(positive regulation of peptidyl-serine dephosphorylation);GO:1903573(negative regulation of response to endoplasmic reticulum stress);GO:1903898(negative regulation of PERK-mediated unfolded protein response);GO:1903912(negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation);GO:1903917(positive regulation of endoplasmic reticulum stress-induced eIF2 alpha dephosphorylation);GO:1990441(negative regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress);GO:0000164(protein phosphatase type 1 complex);GO:0000164(protein phosphatase type 1 complex)","04141(Protein processing in endoplasmic reticulum);04141(Protein processing in endoplasmic reticulum)","K14019","NA","protein phosphatase 1 regulatory subunit 15A [Source:HGNC Symbol;Acc:HGNC:14375]",{"v":14.7633352466861,"d":"14.76"},{"v":29.1950916818623,"d":"29.20"},{"v":0.505678673920998,"d":"0.51"},{"v":-0.98370715818048,"d":"-0.98"},{"v":0.146903764232851,"d":"0.15"},{"v":0.940427826220425,"d":"0.94"},"down","no"]
["MSTRG.7413","VAPA","ENST00000340541;ENST00000400000;ENST00000585042;ENST00000577539;ENST00000577901;ENST00000583879;ENST00000583475;ENST00000584796","GO:0005634(nucleus);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0004871(signal transducer activity);GO:0048471(perinuclear region of cytoplasm);GO:0030054(cell junction);GO:0007165(signal transduction);GO:0008017(microtubule binding);GO:0000139(Golgi membrane);GO:0005923(bicellular tight junction);GO:0045296(cadherin binding);GO:0043312(neutrophil degranulation);GO:0043123(positive regulation of I-kappaB kinase/NF-kappaB signaling);GO:0006888(ER to Golgi vesicle-mediated transport);GO:0061025(membrane fusion);GO:0031965(nuclear membrane);GO:0019904(protein domain specific binding);GO:0046982(protein heterodimerization activity);GO:0031982(vesicle);GO:0035577(azurophil granule membrane);GO:0008219(cell death);GO:0030148(sphingolipid biosynthetic process);GO:0031175(neuron projection development);GO:0044828(negative regulation by host of viral genome replication);GO:0033149(FFAT motif binding);GO:0090114(COPII-coated vesicle budding);GO:0044791(positive regulation by host of viral release from host cell);GO:0044829(positive regulation by host of viral genome replication);GO:0070972(protein localization to endoplasmic reticulum);GO:0015630(microtubule cytoskeleton);GO:0015630(microtubule cytoskeleton)","04979(Cholesterol metabolism);04979(Cholesterol metabolism)","K06096","NA","VAMP associated protein A [Source:HGNC Symbol;Acc:HGNC:12648]",{"v":2.6614607446246,"d":"2.66"},{"v":5.26875446193162,"d":"5.27"},{"v":0.505140401560649,"d":"0.51"},{"v":-0.985243660522319,"d":"-0.99"},{"v":0.146986491735509,"d":"0.15"},{"v":0.940427826220425,"d":"0.94"},"down","no"]
["ENSG00000181481","RNF135","ENST00000328381;ENST00000535306;ENST00000324689;ENST00000582674;ENST00000580444;ENST00000434242","GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0016740(transferase activity);GO:0016567(protein ubiquitination);GO:0005515(protein binding);GO:0002376(immune system process);GO:0045087(innate immune response);GO:0042802(identical protein binding);GO:0005829(cytosol);GO:0016579(protein deubiquitination);GO:0043021(ribonucleoprotein complex binding);GO:0004842(ubiquitin-protein transferase activity);GO:0032728(positive regulation of interferon-beta production);GO:0032480(negative regulation of type I interferon production);GO:0045088(regulation of innate immune response);GO:0045088(regulation of innate immune response)","NA","NA","NA","ring finger protein 135 [Source:HGNC Symbol;Acc:HGNC:21158]",{"v":1.61149115223464,"d":"1.61"},{"v":3.20596083463687,"d":"3.21"},{"v":0.502654659665288,"d":"0.50"},{"v":-0.992360533616372,"d":"-0.99"},{"v":0.147024604006676,"d":"0.15"},{"v":0.940427826220425,"d":"0.94"},"down","no"]
["MSTRG.14007","KDM7A","ENST00000397560;ENST00000472616;ENST00000478996","GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0005730(nucleolus);GO:0005654(nucleoplasm);GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0016569(covalent chromatin modification);GO:0008270(zinc ion binding);GO:0007399(nervous system development);GO:0051213(dioxygenase activity);GO:0005506(iron ion binding);GO:0016706(oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors);GO:0032454(histone demethylase activity (H3-K9 specific));GO:0033169(histone H3-K9 demethylation);GO:0032452(histone demethylase activity);GO:0035064(methylated histone binding);GO:0071558(histone demethylase activity (H3-K27 specific));GO:0071557(histone H3-K27 demethylation);GO:0051864(histone demethylase activity (H3-K36 specific));GO:0070544(histone H3-K36 demethylation);GO:0030901(midbrain development);GO:0035575(histone demethylase activity (H4-K20 specific));GO:0035574(histone H4-K20 demethylation);GO:0045893(positive regulation of transcription, DNA-templated);GO:0045893(positive regulation of transcription, DNA-templated)","NA","NA","NA","lysine demethylase 7A [Source:HGNC Symbol;Acc:HGNC:22224]",{"v":4.17231023351007,"d":"4.17"},{"v":8.25101443234358,"d":"8.25"},{"v":0.50567239552446,"d":"0.51"},{"v":-0.983725070479828,"d":"-0.98"},{"v":0.147079673323852,"d":"0.15"},{"v":0.940427826220425,"d":"0.94"},"down","no"]
["MSTRG.6294","OVCA2;DPH1","ENST00000572195;ENST00000263083;ENST00000576129;ENST00000263084;ENST00000575998;ENST00000570477;ENST00000572684;ENST00000570867;ENST00000607788;ENST00000572248;ENST00000571418;ENST00000576891;ENST00000571710;ENST00000575162;ENST00000572214;ENST00000572819","GO:0005737(cytoplasm);GO:0016787(hydrolase activity);GO:0032526(response to retinoic acid);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0016740(transferase activity);GO:0030054(cell junction);GO:0005515(protein binding);GO:0005829(cytosol);GO:0017183(peptidyl-diphthamide biosynthetic process from peptidyl-histidine);GO:0008283(cell proliferation);GO:0008283(cell proliferation)","NA","NA","NA","OVCA2, serine hydrolase domain containing [Source:HGNC Symbol;Acc:HGNC:24203];diphthamide biosynthesis 1 [Source:HGNC Symbol;Acc:HGNC:3003]",{"v":2.17148149696022,"d":"2.17"},{"v":1.13261860656592,"d":"1.13"},{"v":1.91722216496523,"d":"1.92"},{"v":0.939017524133033,"d":"0.94"},{"v":0.147413228858367,"d":"0.15"},{"v":0.940427826220425,"d":"0.94"},"up","no"]
["ENSG00000169193","CCDC126","ENST00000307471;ENST00000484553;ENST00000409765;ENST00000472407;ENST00000448353","GO:0016020(membrane);GO:0005576(extracellular region);GO:0006487(protein N-linked glycosylation);GO:0030144(alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity);GO:0005794(Golgi apparatus);GO:0005794(Golgi apparatus)","NA","NA","NA","coiled-coil domain containing 126 [Source:HGNC Symbol;Acc:HGNC:22398]",{"v":0.927227688732394,"d":"0.93"},{"v":1.84565435295775,"d":"1.85"},{"v":0.502384255885435,"d":"0.50"},{"v":-0.993136842265935,"d":"-0.99"},{"v":0.147553782933401,"d":"0.15"},{"v":0.940427826220425,"d":"0.94"},"down","no"]
["MSTRG.2504","BAD","ENST00000309032;ENST00000394531;ENST00000394532;ENST00000493798;ENST00000492141;ENST00000544271","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005739(mitochondrion);GO:0005829(cytosol);GO:0006915(apoptotic process);GO:0005515(protein binding);GO:0005741(mitochondrial outer membrane);GO:0008656(cysteine-type endopeptidase activator activity involved in apoptotic process);GO:0019903(protein phosphatase binding);GO:0030346(protein phosphatase 2B binding);GO:0043422(protein kinase B binding);GO:0046982(protein heterodimerization activity);GO:0071889(14-3-3 protein binding);GO:0001666(response to hypoxia);GO:0001836(release of cytochrome c from mitochondria);GO:0006007(glucose catabolic process);GO:0006919(activation of cysteine-type endopeptidase activity involved in apoptotic process);GO:0007283(spermatogenesis);GO:0008283(cell proliferation);GO:0008625(extrinsic apoptotic signaling pathway via death domain receptors);GO:0008630(intrinsic apoptotic signaling pathway in response to DNA damage);GO:0009725(response to hormone);GO:0009749(response to glucose);GO:0010033(response to organic substance);GO:0010918(positive regulation of mitochondrial membrane potential);GO:0014070(response to organic cyclic compound);GO:0019050(suppression by virus of host apoptotic process);GO:0019221(cytokine-mediated signaling pathway);GO:0021987(cerebral cortex development);GO:0032024(positive regulation of insulin secretion);GO:0032355(response to estradiol);GO:0032570(response to progesterone);GO:0033133(positive regulation of glucokinase activity);GO:0033574(response to testosterone);GO:0034201(response to oleic acid);GO:0035774(positive regulation of insulin secretion involved in cellular response to glucose stimulus);GO:0042493(response to drug);GO:0042542(response to hydrogen peroxide);GO:0042593(glucose homeostasis);GO:0042981(regulation of apoptotic process);GO:0043065(positive regulation of apoptotic process);GO:0043200(response to amino acid);GO:0043281(regulation of cysteine-type endopeptidase activity involved in apoptotic process);GO:0044342(type B pancreatic cell proliferation);GO:0045471(response to ethanol);GO:0045579(positive regulation of B cell differentiation);GO:0045582(positive regulation of T cell differentiation);GO:0046031(ADP metabolic process);GO:0046034(ATP metabolic process);GO:0051384(response to glucocorticoid);GO:0051592(response to calcium ion);GO:0060139(positive regulation of apoptotic process by virus);GO:0060154(cellular process regulating host cell cycle in response to virus);GO:0071247(cellular response to chromate);GO:0071396(cellular response to lipid);GO:0097190(apoptotic signaling pathway);GO:0097192(extrinsic apoptotic signaling pathway in absence of ligand);GO:1901216(positive regulation of neuron death);GO:1902220(positive regulation of intrinsic apoptotic signaling pathway in response to osmotic stress);GO:2000078(positive regulation of type B pancreatic cell development);GO:0008289(lipid binding);GO:0019901(protein kinase binding);GO:0010508(positive regulation of autophagy);GO:0071260(cellular response to mechanical stimulus);GO:0097191(extrinsic apoptotic signaling pathway);GO:0090200(positive regulation of release of cytochrome c from mitochondria);GO:0005543(phospholipid binding);GO:0043280(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process);GO:0097193(intrinsic apoptotic signaling pathway);GO:0071456(cellular response to hypoxia);GO:1900740(positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway);GO:0050679(positive regulation of epithelial cell proliferation);GO:0001844(protein insertion into mitochondrial membrane involved in apoptotic signaling pathway);GO:2001244(positive regulation of intrinsic apoptotic signaling pathway);GO:0071316(cellular response to nicotine);GO:0046902(regulation of mitochondrial membrane permeability);GO:0046931(pore complex assembly);GO:0045862(positive regulation of proteolysis);GO:0097202(activation of cysteine-type endopeptidase activity);GO:0045918(negative regulation of cytolysis);GO:0045918(negative regulation of cytolysis)","04014(Ras signaling pathway);04012(ErbB signaling pathway);04370(VEGF signaling pathway);04024(cAMP signaling pathway);04022(cGMP - PKG signaling pathway);04151(PI3K-Akt signaling pathway);04140(Autophagy - animal);04210(Apoptosis);04510(Focal adhesion);04910(Insulin signaling pathway);04919(Thyroid hormone signaling pathway);04722(Neurotrophin signaling pathway);05200(Pathways in cancer);05203(Viral carcinogenesis);05210(Colorectal cancer);05212(Pancreatic cancer);05225(Hepatocellular carcinoma);05221(Acute myeloid leukemia);05220(Chronic myeloid leukemia);05218(Melanoma);05211(Renal cell carcinoma);05215(Prostate cancer);05213(Endometrial cancer);05223(Non-small cell lung cancer);05010(Alzheimer's disease);05014(Amyotrophic lateral sclerosis (ALS));05152(Tuberculosis);05161(Hepatitis B);05160(Hepatitis C);05165(Human papillomavirus infection);05145(Toxoplasmosis);01521(EGFR tyrosine kinase inhibitor resistance);01524(Platinum drug resistance);01522(Endocrine resistance);01522(Endocrine resistance)","K02158","NA","BCL2 associated agonist of cell death [Source:HGNC Symbol;Acc:HGNC:936]",{"v":0.891508676229508,"d":"0.89"},{"v":1.81626732318501,"d":"1.82"},{"v":0.490846619795018,"d":"0.49"},{"v":-1.02665581460507,"d":"-1.03"},{"v":0.147764280390339,"d":"0.15"},{"v":0.940427826220425,"d":"0.94"},"down","no"]
["MSTRG.10450","TMEM184B","ENST00000361906;ENST00000633056;ENST00000633438;ENST00000488844;ENST00000474416;ENST00000464059;ENST00000457534;ENST00000466117;ENST00000436674","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005215(transporter activity);GO:0006810(transport);GO:0006810(transport)","NA","NA","NA","transmembrane protein 184B [Source:HGNC Symbol;Acc:HGNC:1310]",{"v":3.6928856809322,"d":"3.69"},{"v":7.29750679110169,"d":"7.30"},{"v":0.506047584009811,"d":"0.51"},{"v":-0.982655045961232,"d":"-0.98"},{"v":0.147838024781211,"d":"0.15"},{"v":0.940427826220425,"d":"0.94"},"down","no"]
["MSTRG.2963","FOXRED1","ENST00000263578;ENST00000524751;ENST00000530642;ENST00000532590;ENST00000526366;ENST00000525770;ENST00000534315;ENST00000533395;ENST00000525083;ENST00000526525;ENST00000532125;ENST00000534011;ENST00000529802;ENST00000527004;ENST00000527875","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0005739(mitochondrion);GO:0005743(mitochondrial inner membrane);GO:0070469(respiratory chain);GO:0008150(biological_process);GO:0032981(mitochondrial respiratory chain complex I assembly);GO:0005747(mitochondrial respiratory chain complex I);GO:0005747(mitochondrial respiratory chain complex I)","NA","NA","NA","FAD dependent oxidoreductase domain containing 1 [Source:HGNC Symbol;Acc:HGNC:26927]",{"v":1.18519899098462,"d":"1.19"},{"v":0.610016557539332,"d":"0.61"},{"v":1.94289642852555,"d":"1.94"},{"v":0.958208996118743,"d":"0.96"},{"v":0.147959322327001,"d":"0.15"},{"v":0.940427826220425,"d":"0.94"},"up","no"]
["MSTRG.12900","PPT2;PPT2-EGFL8;EGFL8","ENST00000324816;ENST00000436118;ENST00000422437;ENST00000482938;ENST00000428388;ENST00000421600;ENST00000495908;ENST00000333845;ENST00000453656;ENST00000466239;ENST00000479001;ENST00000583227;ENST00000395512;ENST00000375143;ENST00000493548;ENST00000432129","GO:0008474(palmitoyl-(protein) hydrolase activity);GO:0016790(thiolester hydrolase activity);GO:0098734(macromolecule depalmitoylation);GO:0016787(hydrolase activity);GO:0005764(lysosome);GO:0098599(palmitoyl hydrolase activity);GO:0070062(extracellular exosome);GO:0043202(lysosomal lumen);GO:0046949(fatty-acyl-CoA biosynthetic process);GO:0043231(intracellular membrane-bounded organelle);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005509(calcium ion binding);GO:0005576(extracellular region);GO:0005576(extracellular region)","00062(Fatty acid elongation);04142(Lysosome);04142(Lysosome)","K01074","EC:3.1.2.22","palmitoyl-protein thioesterase 2 [Source:HGNC Symbol;Acc:HGNC:9326];PPT2-EGFL8 readthrough (NMD candidate) [Source:HGNC Symbol;Acc:HGNC:48343];EGF like domain multiple 8 [Source:HGNC Symbol;Acc:HGNC:13944]",{"v":1.00401498647475,"d":"1.00"},{"v":0.522186449559499,"d":"0.52"},{"v":1.9227135964974,"d":"1.92"},{"v":0.943143877765922,"d":"0.94"},{"v":0.148082506557474,"d":"0.15"},{"v":0.940427826220425,"d":"0.94"},"up","no"]
["MSTRG.12264","ATG12","ENST00000509910;ENST00000505252;ENST00000513322;ENST00000500945;ENST00000509598;ENST00000513167;ENST00000508464;ENST00000505993;ENST00000507793;ENST00000514775;ENST00000379594;ENST00000511984;ENST00000513292","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005515(protein binding);GO:0006914(autophagy);GO:0000045(autophagosome assembly);GO:0002376(immune system process);GO:0045087(innate immune response);GO:0034045(pre-autophagosomal structure membrane);GO:0005829(cytosol);GO:0000422(mitophagy);GO:0044804(nucleophagy);GO:0030670(phagocytic vesicle membrane);GO:0016236(macroautophagy);GO:0005776(autophagosome);GO:0019776(Atg8 ligase activity);GO:0006501(C-terminal protein lipidation);GO:0034274(Atg12-Atg5-Atg16 complex);GO:0043234(protein complex);GO:0043234(protein complex)","04068(FoxO signaling pathway);04140(Autophagy - animal);04136(Autophagy - other eukaryotes);04621(NOD-like receptor signaling pathway);04622(RIG-I-like receptor signaling pathway);04622(RIG-I-like receptor signaling pathway)","K08336","NA","autophagy related 12 [Source:HGNC Symbol;Acc:HGNC:588]",{"v":1.10900888737624,"d":"1.11"},{"v":2.20297359619712,"d":"2.20"},{"v":0.503414516311346,"d":"0.50"},{"v":-0.99018127666332,"d":"-0.99"},{"v":0.148234879876888,"d":"0.15"},{"v":0.940427826220425,"d":"0.94"},"down","no"]
["MSTRG.14244","DOCK5","MSTRG.14244.10;ENST00000521405;ENST00000276440;ENST00000479547;ENST00000481728;ENST00000467709;ENST00000444569;ENST00000487948;ENST00000481100;ENST00000410074;ENST00000478099;ENST00000463457","GO:0005622(intracellular);GO:0007264(small GTPase mediated signal transduction);GO:0043547(positive regulation of GTPase activity);GO:0005085(guanyl-nucleotide exchange factor activity);GO:1904754(positive regulation of vascular associated smooth muscle cell migration);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0010634(positive regulation of epithelial cell migration);GO:1900026(positive regulation of substrate adhesion-dependent cell spreading);GO:1904694(negative regulation of vascular smooth muscle contraction);GO:1904694(negative regulation of vascular smooth muscle contraction)","NA","NA","NA","dedicator of cytokinesis 5 [Source:HGNC Symbol;Acc:HGNC:23476]",{"v":4.47364322522747,"d":"4.47"},{"v":8.82657457036021,"d":"8.83"},{"v":0.506837979962243,"d":"0.51"},{"v":-0.980403457839282,"d":"-0.98"},{"v":0.148270249961425,"d":"0.15"},{"v":0.940427826220425,"d":"0.94"},"down","no"]
["MSTRG.1168","CREG1","ENST00000370509;ENST00000466652","GO:0005576(extracellular region);GO:0048037(cofactor binding);GO:0005615(extracellular space);GO:1903507(negative regulation of nucleic acid-templated transcription);GO:0070062(extracellular exosome);GO:0040008(regulation of growth);GO:0043312(neutrophil degranulation);GO:0007275(multicellular organism development);GO:0003714(transcription corepressor activity);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0008283(cell proliferation);GO:0035578(azurophil granule lumen);GO:0008134(transcription factor binding);GO:0006355(regulation of transcription, DNA-templated);GO:0005667(transcription factor complex);GO:0005667(transcription factor complex)","NA","NA","NA","cellular repressor of E1A stimulated genes 1 [Source:HGNC Symbol;Acc:HGNC:2351]",{"v":5.761407609375,"d":"5.76"},{"v":11.3891273556548,"d":"11.39"},{"v":0.505869100367414,"d":"0.51"},{"v":-0.983163976137819,"d":"-0.98"},{"v":0.148289501611177,"d":"0.15"},{"v":0.940427826220425,"d":"0.94"},"down","no"]
["MSTRG.10514","POLR3H","ENST00000337566;ENST00000396504;ENST00000432789;ENST00000407461;ENST00000355209;ENST00000483837;ENST00000431534;ENST00000442616","GO:0005634(nucleus);GO:0043231(intracellular membrane-bounded organelle);GO:0005654(nucleoplasm);GO:0003677(DNA binding);GO:0005813(centrosome);GO:0006351(transcription, DNA-templated);GO:0003899(DNA-directed 5'-3' RNA polymerase activity);GO:0002376(immune system process);GO:0045087(innate immune response);GO:0051607(defense response to virus);GO:0005829(cytosol);GO:0001056(RNA polymerase III activity);GO:0032481(positive regulation of type I interferon production);GO:0006383(transcription from RNA polymerase III promoter);GO:0006384(transcription initiation from RNA polymerase III promoter);GO:0006139(nucleobase-containing compound metabolic process);GO:0005666(DNA-directed RNA polymerase III complex);GO:0005666(DNA-directed RNA polymerase III complex)","00230(Purine metabolism);00240(Pyrimidine metabolism);03020(RNA polymerase);04623(Cytosolic DNA-sensing pathway);05169(Epstein-Barr virus infection);05169(Epstein-Barr virus infection)","K03022","NA","RNA polymerase III subunit H [Source:HGNC Symbol;Acc:HGNC:30349]",{"v":0.986753247801031,"d":"0.99"},{"v":1.96132237170155,"d":"1.96"},{"v":0.503106099251277,"d":"0.50"},{"v":-0.991065415090556,"d":"-0.99"},{"v":0.148299516337259,"d":"0.15"},{"v":0.940427826220425,"d":"0.94"},"down","no"]
["ENSG00000119559","C19orf25","ENST00000588849;ENST00000592872;ENST00000436106;ENST00000427685;ENST00000592605;ENST00000589421;ENST00000586564;ENST00000592486;ENST00000590621;ENST00000585675;ENST00000588427","GO:0005515(protein binding);GO:0005515(protein binding)","NA","NA","NA","chromosome 19 open reading frame 25 [Source:HGNC Symbol;Acc:HGNC:26711]",{"v":0.649196929759343,"d":"0.65"},{"v":0.331837584621405,"d":"0.33"},{"v":1.95636950076048,"d":"1.96"},{"v":0.968178878761668,"d":"0.97"},{"v":0.148300330578304,"d":"0.15"},{"v":0.940427826220425,"d":"0.94"},"up","no"]
["ENSG00000165113","GKAP1","ENST00000376365;ENST00000485742;ENST00000388782;ENST00000376371;ENST00000491634;ENST00000376362","GO:0007165(signal transduction);GO:0005794(Golgi apparatus);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0005515(protein binding);GO:0042802(identical protein binding);GO:0042802(identical protein binding)","NA","NA","NA","G kinase anchoring protein 1 [Source:HGNC Symbol;Acc:HGNC:17496]",{"v":0.325489778467909,"d":"0.33"},{"v":0.670145994676131,"d":"0.67"},{"v":0.485699804301915,"d":"0.49"},{"v":-1.04186318981606,"d":"-1.04"},{"v":0.148310100253762,"d":"0.15"},{"v":0.940427826220425,"d":"0.94"},"down","no"]
["MSTRG.2436","VPS37C","ENST00000301765;ENST00000538036;ENST00000535818;ENST00000536000","GO:0006810(transport);GO:0016020(membrane);GO:0015031(protein transport);GO:0046983(protein dimerization activity);GO:0005515(protein binding);GO:0005768(endosome);GO:0031902(late endosome membrane);GO:0070062(extracellular exosome);GO:0048306(calcium-dependent protein binding);GO:0016197(endosomal transport);GO:0016236(macroautophagy);GO:0019058(viral life cycle);GO:0036258(multivesicular body assembly);GO:0039702(viral budding via host ESCRT complex);GO:0075733(intracellular transport of virus);GO:0000813(ESCRT I complex);GO:0010008(endosome membrane);GO:0043657(host cell);GO:0043657(host cell)","04144(Endocytosis);04144(Endocytosis)","K12185","NA","VPS37C, ESCRT-I subunit [Source:HGNC Symbol;Acc:HGNC:26097]",{"v":1.77625410606061,"d":"1.78"},{"v":3.52527406439394,"d":"3.53"},{"v":0.503862699357527,"d":"0.50"},{"v":-0.988897436443871,"d":"-0.99"},{"v":0.148420095011044,"d":"0.15"},{"v":0.940427826220425,"d":"0.94"},"down","no"]
["MSTRG.11483","CTBP1-AS","ENST00000625256","NA","NA","NA","NA","CTBP1 antisense RNA [Source:HGNC Symbol;Acc:HGNC:48337]",{"v":0.387975,"d":"0.39"},{"v":0.19575,"d":"0.20"},{"v":1.98199233716475,"d":"1.98"},{"v":0.986951384746508,"d":"0.99"},{"v":0.148423149713127,"d":"0.15"},{"v":0.940427826220425,"d":"0.94"},"up","no"]
["ENSG00000144843","ADPRH","ENST00000478399;ENST00000478927;ENST00000357003;ENST00000481816;ENST00000465513","GO:0000287(magnesium ion binding);GO:0016787(hydrolase activity);GO:0005515(protein binding);GO:0005622(intracellular);GO:0006464(cellular protein modification process);GO:0030955(potassium ion binding);GO:0003875(ADP-ribosylarginine hydrolase activity);GO:0051725(protein de-ADP-ribosylation);GO:0051725(protein de-ADP-ribosylation)","NA","NA","NA","ADP-ribosylarginine hydrolase [Source:HGNC Symbol;Acc:HGNC:269]",{"v":0.679172242903575,"d":"0.68"},{"v":1.36119172654388,"d":"1.36"},{"v":0.498954136775442,"d":"0.50"},{"v":-1.00302088390902,"d":"-1.00"},{"v":0.14848772911226,"d":"0.15"},{"v":0.940427826220425,"d":"0.94"},"down","no"]
["ENSG00000189223","PAX8-AS1","ENST00000445745;ENST00000422956;ENST00000623306;ENST00000451179;ENST00000617278;ENST00000623031;ENST00000436293;ENST00000617509;ENST00000609210;ENST00000613966;ENST00000510859;ENST00000333145;ENST00000556070","NA","NA","NA","NA","PAX8 antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:49271]",{"v":0.127596398691675,"d":"0.13"},{"v":0.0651552773532477,"d":"0.07"},{"v":1.95834326665352,"d":"1.96"},{"v":0.969633668768612,"d":"0.97"},{"v":0.148511971569789,"d":"0.15"},{"v":0.940427826220425,"d":"0.94"},"up","no"]
["ENSG00000164687","FABP5","ENST00000297258;ENST00000481695;ENST00000486269;ENST00000396359","GO:0006810(transport);GO:0005737(cytoplasm);GO:0005215(transporter activity);GO:0008289(lipid binding);GO:0005576(extracellular region);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0019433(triglyceride catabolic process);GO:0043312(neutrophil degranulation);GO:0006006(glucose metabolic process);GO:0006629(lipid metabolic process);GO:0006656(phosphatidylcholine biosynthetic process);GO:0015758(glucose transport);GO:0030667(secretory granule membrane);GO:0035578(azurophil granule lumen);GO:0008544(epidermis development);GO:0005504(fatty acid binding);GO:0005504(fatty acid binding)","03320(PPAR signaling pathway);03320(PPAR signaling pathway)","K08754","NA","fatty acid binding protein 5 [Source:HGNC Symbol;Acc:HGNC:3560]",{"v":2.096884807896,"d":"2.10"},{"v":1.07589987385652,"d":"1.08"},{"v":1.94895906101355,"d":"1.95"},{"v":0.962703786289468,"d":"0.96"},{"v":0.148589955768718,"d":"0.15"},{"v":0.940427826220425,"d":"0.94"},"up","no"]
["ENSG00000198862","LTN1","ENST00000389195;ENST00000614971;ENST00000475344;ENST00000361371;ENST00000389194;ENST00000483326","GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0016740(transferase activity);GO:0016567(protein ubiquitination);GO:0005515(protein binding);GO:0004842(ubiquitin-protein transferase activity);GO:0061630(ubiquitin protein ligase activity);GO:0051865(protein autoubiquitination);GO:0051865(protein autoubiquitination)","NA","NA","NA","listerin E3 ubiquitin protein ligase 1 [Source:HGNC Symbol;Acc:HGNC:13082]",{"v":1.19674610590356,"d":"1.20"},{"v":2.36926027174403,"d":"2.37"},{"v":0.505113819775751,"d":"0.51"},{"v":-0.985319580837126,"d":"-0.99"},{"v":0.148635622454818,"d":"0.15"},{"v":0.940427826220425,"d":"0.94"},"down","no"]
["MSTRG.6410","TRAPPC1;KCNAB3","ENST00000303731;ENST00000303790;ENST00000540486;ENST00000572656;ENST00000574006;ENST00000570587;ENST00000575639;ENST00000571739;ENST00000572275;ENST00000570852;ENST00000573989;ENST00000571947;ENST00000576981","GO:0006810(transport);GO:0030008(TRAPP complex);GO:0005794(Golgi apparatus);GO:0005783(endoplasmic reticulum);GO:0043547(positive regulation of GTPase activity);GO:0005576(extracellular region);GO:0016192(vesicle-mediated transport);GO:0000139(Golgi membrane);GO:0005829(cytosol);GO:0017112(Rab guanyl-nucleotide exchange factor activity);GO:0061024(membrane organization);GO:0043312(neutrophil degranulation);GO:0006888(ER to Golgi vesicle-mediated transport);GO:0035578(azurophil granule lumen);GO:0048208(COPII vesicle coating);GO:0005737(cytoplasm);GO:0016021(integral component of membrane);GO:0005244(voltage-gated ion channel activity);GO:0005249(voltage-gated potassium channel activity);GO:0006811(ion transport);GO:0006813(potassium ion transport);GO:0034765(regulation of ion transmembrane transport);GO:0071805(potassium ion transmembrane transport);GO:0065009(regulation of molecular function);GO:0005886(plasma membrane);GO:0015459(potassium channel regulator activity);GO:0015459(potassium channel regulator activity)","NA","NA","NA","trafficking protein particle complex 1 [Source:HGNC Symbol;Acc:HGNC:19894];potassium voltage-gated channel subfamily A regulatory beta subunit 3 [Source:HGNC Symbol;Acc:HGNC:6230]",{"v":3.84039461815336,"d":"3.84"},{"v":7.5864572305686,"d":"7.59"},{"v":0.506217131585348,"d":"0.51"},{"v":-0.982171762399253,"d":"-0.98"},{"v":0.148763620833976,"d":"0.15"},{"v":0.940427826220425,"d":"0.94"},"down","no"]
["MSTRG.10488","XPNPEP3","ENST00000357137;ENST00000465258;ENST00000417688;ENST00000482652","GO:0046872(metal ion binding);GO:0016787(hydrolase activity);GO:0005739(mitochondrion);GO:0008233(peptidase activity);GO:0006508(proteolysis);GO:0030145(manganese ion binding);GO:0008237(metallopeptidase activity);GO:0004177(aminopeptidase activity);GO:0070062(extracellular exosome);GO:0016485(protein processing);GO:0003094(glomerular filtration);GO:0003094(glomerular filtration)","NA","NA","NA","X-prolyl aminopeptidase 3 [Source:HGNC Symbol;Acc:HGNC:28052]",{"v":0.597965065803217,"d":"0.60"},{"v":0.309643376018383,"d":"0.31"},{"v":1.93114115177364,"d":"1.93"},{"v":0.949453618209549,"d":"0.95"},{"v":0.148780807805988,"d":"0.15"},{"v":0.940427826220425,"d":"0.94"},"up","no"]
["ENSG00000251615","AC104825.2","ENST00000505448","NA","NA","NA","NA",null,{"v":0.563382,"d":"0.56"},{"v":0.281925,"d":"0.28"},{"v":1.99833998403831,"d":"2.00"},{"v":0.998802054381121,"d":"1.00"},{"v":0.148857333266689,"d":"0.15"},{"v":0.940427826220425,"d":"0.94"},"up","no"]
["MSTRG.12541","ERGIC1","ENST00000520399;ENST00000393784;ENST00000326654;ENST00000523215;ENST00000519567;ENST00000520326;ENST00000523291;ENST00000523650;ENST00000523366;ENST00000519860;ENST00000521392;ENST00000520642;ENST00000519796","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0043231(intracellular membrane-bounded organelle);GO:0005654(nucleoplasm);GO:0005794(Golgi apparatus);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0000139(Golgi membrane);GO:0016192(vesicle-mediated transport);GO:0005515(protein binding);GO:0033116(endoplasmic reticulum-Golgi intermediate compartment membrane);GO:0006888(ER to Golgi vesicle-mediated transport);GO:0005793(endoplasmic reticulum-Golgi intermediate compartment);GO:0005793(endoplasmic reticulum-Golgi intermediate compartment)","NA","NA","NA","endoplasmic reticulum-golgi intermediate compartment 1 [Source:HGNC Symbol;Acc:HGNC:29205]",{"v":11.8796854816465,"d":"11.88"},{"v":23.4035224050499,"d":"23.40"},{"v":0.507602457272977,"d":"0.51"},{"v":-0.978229041691485,"d":"-0.98"},{"v":0.1489050254856,"d":"0.15"},{"v":0.940427826220425,"d":"0.94"},"down","no"]
["ENSG00000244479","OR2A1-AS1","ENST00000462305;ENST00000488041;ENST00000475089;ENST00000493539;ENST00000486094;ENST00000496968;ENST00000467944;ENST00000468575;ENST00000470435","NA","NA","NA","NA","OR2A1 antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:49168]",{"v":0.960534716034755,"d":"0.96"},{"v":0.486105802922591,"d":"0.49"},{"v":1.97597870722748,"d":"1.98"},{"v":0.982567400797672,"d":"0.98"},{"v":0.149347541256511,"d":"0.15"},{"v":0.940427826220425,"d":"0.94"},"up","no"]
["MSTRG.6706","AC015911.3","ENST00000592908","NA","NA","NA","NA",null,{"v":2.914873,"d":"2.91"},{"v":1.486221,"d":"1.49"},{"v":1.96126484553778,"d":"1.96"},{"v":0.971784367526156,"d":"0.97"},{"v":0.149347541256511,"d":"0.15"},{"v":0.940427826220425,"d":"0.94"},"up","no"]
["MSTRG.3076","SPSB2","ENST00000432205;ENST00000523102;ENST00000437851;ENST00000519357;ENST00000524270","GO:0005737(cytoplasm);GO:0016567(protein ubiquitination);GO:0035556(intracellular signal transduction);GO:0005515(protein binding);GO:0003674(molecular_function);GO:0008150(biological_process);GO:0005575(cellular_component);GO:0005829(cytosol);GO:0043687(post-translational protein modification);GO:0043687(post-translational protein modification)","NA","NA","NA","splA/ryanodine receptor domain and SOCS box containing 2 [Source:HGNC Symbol;Acc:HGNC:29522]",{"v":0.863195150489396,"d":"0.86"},{"v":0.430343463295269,"d":"0.43"},{"v":2.00582842337061,"d":"2.01"},{"v":1.00419820448503,"d":"1.00"},{"v":0.149364758514302,"d":"0.15"},{"v":0.940427826220425,"d":"0.94"},"up","no"]
["MSTRG.9766",null,"MSTRG.9766.1","NA","NA","NA","NA",null,{"v":8.813971,"d":"8.81"},{"v":17.360628,"d":"17.36"},{"v":0.507698857437646,"d":"0.51"},{"v":-0.977955081561795,"d":"-0.98"},{"v":0.149548117447567,"d":"0.15"},{"v":0.940427826220425,"d":"0.94"},"down","no"]
["ENSG00000105609","LILRB5","ENST00000621581;ENST00000615654;ENST00000316219;ENST00000449561","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0002376(immune system process);GO:0002250(adaptive immune response);GO:0007166(cell surface receptor signaling pathway);GO:0004888(transmembrane signaling receptor activity);GO:0006952(defense response);GO:0006952(defense response)","04380(Osteoclast differentiation);04380(Osteoclast differentiation)","K06512","NA","leukocyte immunoglobulin like receptor B5 [Source:HGNC Symbol;Acc:HGNC:6609]",{"v":0.197832625053442,"d":"0.20"},{"v":0.399277012683483,"d":"0.40"},{"v":0.495477121820356,"d":"0.50"},{"v":-1.0131096509939,"d":"-1.01"},{"v":0.149672465012567,"d":"0.15"},{"v":0.940427826220425,"d":"0.94"},"down","no"]
["MSTRG.4664","EVL","MSTRG.4664.6;ENST00000555848;ENST00000556258;ENST00000544450;ENST00000402714;ENST00000392920;ENST00000555048;ENST00000554031;ENST00000553910;ENST00000557637;ENST00000553694;ENST00000556921;ENST00000557023;ENST00000554695;ENST00000553875;MSTRG.4664.5;ENST00000554518;ENST00000553771;ENST00000554045;ENST00000557153;ENST00000555706;ENST00000553799;ENST00000555606;ENST00000554460;ENST00000557384","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0003779(actin binding);GO:0017124(SH3 domain binding);GO:0008154(actin polymerization or depolymerization);GO:0051289(protein homotetramerization);GO:0005856(cytoskeleton);GO:0042995(cell projection);GO:0005515(protein binding);GO:0007399(nervous system development);GO:0045010(actin nucleation);GO:0005925(focal adhesion);GO:0005829(cytosol);GO:0030027(lamellipodium);GO:0007411(axon guidance);GO:0051496(positive regulation of stress fiber assembly);GO:0009887(animal organ morphogenesis);GO:0007166(cell surface receptor signaling pathway);GO:0007015(actin filament organization);GO:0010633(negative regulation of epithelial cell migration);GO:1900028(negative regulation of ruffle assembly);GO:0005522(profilin binding);GO:0030838(positive regulation of actin filament polymerization);GO:0030838(positive regulation of actin filament polymerization)","NA","NA","NA","Enah/Vasp-like [Source:HGNC Symbol;Acc:HGNC:20234]",{"v":13.5691118412579,"d":"13.57"},{"v":7.15631774173807,"d":"7.16"},{"v":1.89610248328107,"d":"1.90"},{"v":0.923036943205388,"d":"0.92"},{"v":0.149705390146899,"d":"0.15"},{"v":0.940427826220425,"d":"0.94"},"up","no"]
["MSTRG.11530","SLC2A9","ENST00000506583;ENST00000506839;ENST00000264784;ENST00000509214;ENST00000512342;ENST00000481042;ENST00000505104","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005215(transporter activity);GO:0055085(transmembrane transport);GO:0005886(plasma membrane);GO:0022857(transmembrane transporter activity);GO:0022891(substrate-specific transmembrane transporter activity);GO:0008643(carbohydrate transport);GO:1904659(glucose transmembrane transport);GO:0015992(proton transport);GO:1903825(organic acid transmembrane transport);GO:0015711(organic anion transport);GO:0008645(hexose transport);GO:0016323(basolateral plasma membrane);GO:0016324(apical plasma membrane);GO:0015143(urate transmembrane transporter activity);GO:0046415(urate metabolic process);GO:0005351(sugar:proton symporter activity);GO:0015758(glucose transport);GO:0005355(glucose transmembrane transporter activity);GO:0005355(glucose transmembrane transporter activity)","NA","NA","NA","solute carrier family 2 member 9 [Source:HGNC Symbol;Acc:HGNC:13446]",{"v":0.260546579679468,"d":"0.26"},{"v":0.529028199274267,"d":"0.53"},{"v":0.492500362054219,"d":"0.49"},{"v":-1.02180330974244,"d":"-1.02"},{"v":0.149706728242205,"d":"0.15"},{"v":0.940427826220425,"d":"0.94"},"down","no"]
["ENSG00000137310","TCF19","ENST00000376255;ENST00000542218;ENST00000376257","GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0005515(protein binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0008283(cell proliferation);GO:0008283(cell proliferation)","NA","NA","NA","transcription factor 19 [Source:HGNC Symbol;Acc:HGNC:11629]",{"v":0.589762531656303,"d":"0.59"},{"v":1.18240215234596,"d":"1.18"},{"v":0.498783371195813,"d":"0.50"},{"v":-1.00351472653862,"d":"-1.00"},{"v":0.149722771427234,"d":"0.15"},{"v":0.940427826220425,"d":"0.94"},"down","no"]
["MSTRG.6303","TRPV1;SHPK;AC027796.3","ENST00000572705;ENST00000570742;ENST00000225519;ENST00000399756;ENST00000571088;ENST00000399759;ENST00000572919","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0055085(transmembrane transport);GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0005216(ion channel activity);GO:0006811(ion transport);GO:0005886(plasma membrane);GO:0042995(cell projection);GO:0006816(calcium ion transport);GO:0065009(regulation of molecular function);GO:0030054(cell junction);GO:0045202(synapse);GO:0045211(postsynaptic membrane);GO:0005262(calcium channel activity);GO:0070588(calcium ion transmembrane transport);GO:0060079(excitatory postsynaptic potential);GO:0051209(release of sequestered calcium ion into cytosol);GO:0005516(calmodulin binding);GO:0005887(integral component of plasma membrane);GO:0035091(phosphatidylinositol binding);GO:0032591(dendritic spine membrane);GO:0004888(transmembrane signaling receptor activity);GO:0031226(intrinsic component of plasma membrane);GO:0007166(cell surface receptor signaling pathway);GO:0051289(protein homotetramerization);GO:0051219(phosphoprotein binding);GO:0034605(cellular response to heat);GO:0015278(calcium-release channel activity);GO:0071318(cellular response to ATP);GO:0098703(calcium ion import across plasma membrane);GO:0071468(cellular response to acidic pH);GO:0071312(cellular response to alkaloid);GO:0007635(chemosensory behavior);GO:0005230(extracellular ligand-gated ion channel activity);GO:0005231(excitatory extracellular ligand-gated ion channel activity);GO:0050955(thermoception);GO:1901594(response to capsazepine);GO:0005261(cation channel activity);GO:0008324(cation transmembrane transporter activity);GO:0015276(ligand-gated ion channel activity);GO:0017081(chloride channel regulator activity);GO:0042802(identical protein binding);GO:0097603(temperature-gated ion channel activity);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0001659(temperature homeostasis);GO:0001660(fever generation);GO:0001774(microglial cell activation);GO:0002024(diet induced thermogenesis);GO:0002790(peptide secretion);GO:0006629(lipid metabolic process);GO:0006954(inflammatory response);GO:0007204(positive regulation of cytosolic calcium ion concentration);GO:0009268(response to pH);GO:0009408(response to heat);GO:0010243(response to organonitrogen compound);GO:0014047(glutamate secretion);GO:0014832(urinary bladder smooth muscle contraction);GO:0019233(sensory perception of pain);GO:0034220(ion transmembrane transport);GO:0043065(positive regulation of apoptotic process);GO:0043434(response to peptide hormone);GO:0045429(positive regulation of nitric oxide biosynthetic process);GO:0048265(response to pain);GO:0048266(behavioral response to pain);GO:0050954(sensory perception of mechanical stimulus);GO:0050960(detection of temperature stimulus involved in thermoception);GO:0050965(detection of temperature stimulus involved in sensory perception of pain);GO:0050968(detection of chemical stimulus involved in sensory perception of pain);GO:0060083(smooth muscle contraction involved in micturition);GO:0060454(positive regulation of gastric acid secretion);GO:0071345(cellular response to cytokine stimulus);GO:0071356(cellular response to tumor necrosis factor);GO:0071363(cellular response to growth factor stimulus);GO:0071502(cellular response to temperature stimulus);GO:0090212(negative regulation of establishment of blood-brain barrier);GO:1990090(cellular response to nerve growth factor stimulus);GO:0005829(cytosol);GO:0009897(external side of plasma membrane);GO:0030425(dendrite);GO:0043005(neuron projection);GO:0043025(neuronal cell body);GO:0005737(cytoplasm);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0016773(phosphotransferase activity, alcohol group as acceptor);GO:0005975(carbohydrate metabolic process);GO:0071222(cellular response to lipopolysaccharide);GO:0050727(regulation of inflammatory response);GO:0006098(pentose-phosphate shunt);GO:0043030(regulation of macrophage activation);GO:0035963(cellular response to interleukin-13);GO:0071353(cellular response to interleukin-4);GO:0009052(pentose-phosphate shunt, non-oxidative branch);GO:0050277(sedoheptulokinase activity);GO:0005975(carbohydrate metabolic process)","04080(Neuroactive ligand-receptor interaction);04750(Inflammatory mediator regulation of TRP channels);04750(Inflammatory mediator regulation of TRP channels)","K05222","NA","transient receptor potential cation channel subfamily V member 1 [Source:HGNC Symbol;Acc:HGNC:12716];sedoheptulokinase [Source:HGNC Symbol;Acc:HGNC:1492]",{"v":0.572431487304274,"d":"0.57"},{"v":0.298244551946678,"d":"0.30"},{"v":1.91933593947633,"d":"1.92"},{"v":0.940607247124455,"d":"0.94"},{"v":0.149918428104751,"d":"0.15"},{"v":0.940427826220425,"d":"0.94"},"up","no"]
["MSTRG.6479","MPRIP","ENST00000313485;ENST00000395811;ENST00000578209;ENST00000462033;ENST00000395806;ENST00000341712;ENST00000581955;ENST00000429184;ENST00000414263;ENST00000395807;MSTRG.6479.8;ENST00000579361;ENST00000578548","GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0003779(actin binding);GO:0015629(actin cytoskeleton);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0005925(focal adhesion);GO:0045296(cadherin binding);GO:0045296(cadherin binding)","NA","NA","NA","myosin phosphatase Rho interacting protein [Source:HGNC Symbol;Acc:HGNC:30321]",{"v":4.45247341532075,"d":"4.45"},{"v":2.34473301086215,"d":"2.34"},{"v":1.89892554704281,"d":"1.90"},{"v":0.925183341496992,"d":"0.93"},{"v":0.149945994992629,"d":"0.15"},{"v":0.940427826220425,"d":"0.94"},"up","no"]
["MSTRG.2111","C11orf21","MSTRG.2111.1;ENST00000381153;ENST00000456145;ENST00000470369;ENST00000495467","GO:0005737(cytoplasm);GO:0005737(cytoplasm)","NA","NA","NA","chromosome 11 open reading frame 21 [Source:HGNC Symbol;Acc:HGNC:13231]",{"v":14.8519134034451,"d":"14.85"},{"v":7.82448729623753,"d":"7.82"},{"v":1.89813247068428,"d":"1.90"},{"v":0.924580681574073,"d":"0.92"},{"v":0.149957406793712,"d":"0.15"},{"v":0.940427826220425,"d":"0.94"},"up","no"]
["MSTRG.5472","HBQ1","ENST00000199708","GO:0006810(transport);GO:0046872(metal ion binding);GO:0005506(iron ion binding);GO:0005515(protein binding);GO:0020037(heme binding);GO:0005344(oxygen transporter activity);GO:0019825(oxygen binding);GO:0015671(oxygen transport);GO:0005833(hemoglobin complex)","NA","NA","NA","hemoglobin subunit theta 1 [Source:HGNC Symbol;Acc:HGNC:4833]",{"v":55.872231,"d":"55.87"},{"v":29.429832,"d":"29.43"},{"v":1.89848963459934,"d":"1.90"},{"v":0.92485212213164,"d":"0.92"},{"v":0.150226819524921,"d":"0.15"},{"v":0.940427826220425,"d":"0.94"},"up","no"]
["MSTRG.8841","HK2","ENST00000290573;ENST00000409174;ENST00000472302","GO:0016020(membrane);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0006096(glycolytic process);GO:0004396(hexokinase activity);GO:0005536(glucose binding);GO:0016773(phosphotransferase activity, alcohol group as acceptor);GO:0001678(cellular glucose homeostasis);GO:0005975(carbohydrate metabolic process);GO:0046835(carbohydrate phosphorylation);GO:0051156(glucose 6-phosphate metabolic process);GO:0005739(mitochondrion);GO:0005515(protein binding);GO:0003824(catalytic activity);GO:0008152(metabolic process);GO:0005741(mitochondrial outer membrane);GO:0005829(cytosol);GO:0061621(canonical glycolysis);GO:0004340(glucokinase activity);GO:0008865(fructokinase activity);GO:0019158(mannokinase activity);GO:0019318(hexose metabolic process);GO:0072655(establishment of protein localization to mitochondrion);GO:0072656(maintenance of protein location in mitochondrion);GO:0002931(response to ischemia);GO:0006006(glucose metabolic process);GO:0007595(lactation);GO:0008637(apoptotic mitochondrial changes);GO:0035795(negative regulation of mitochondrial membrane permeability);GO:0046324(regulation of glucose import);GO:1904925(positive regulation of mitophagy in response to mitochondrial depolarization);GO:1990830(cellular response to leukemia inhibitory factor);GO:2000378(negative regulation of reactive oxygen species metabolic process);GO:0005623(cell);GO:0005623(cell)","00010(Glycolysis / Gluconeogenesis);00051(Fructose and mannose metabolism);00052(Galactose metabolism);00500(Starch and sucrose metabolism);00520(Amino sugar and nucleotide sugar metabolism);00524(Neomycin, kanamycin and gentamicin biosynthesis);04066(HIF-1 signaling pathway);04910(Insulin signaling pathway);04973(Carbohydrate digestion and absorption);05230(Central carbon metabolism in cancer);04930(Type II diabetes mellitus);04930(Type II diabetes mellitus)","K00844","EC:2.7.1.1","hexokinase 2 [Source:HGNC Symbol;Acc:HGNC:4923]",{"v":3.64156820217678,"d":"3.64"},{"v":7.16906297641821,"d":"7.17"},{"v":0.507955951029485,"d":"0.51"},{"v":-0.977224700225892,"d":"-0.98"},{"v":0.150249282294796,"d":"0.15"},{"v":0.940427826220425,"d":"0.94"},"down","no"]
["ENSG00000172037","LAMB2","ENST00000418109;ENST00000488638;ENST00000467506;ENST00000483057;ENST00000477225;ENST00000480640;ENST00000494831;ENST00000464891;ENST00000469665;ENST00000542580;ENST00000498377","GO:0007155(cell adhesion);GO:0005576(extracellular region);GO:0005578(proteinaceous extracellular matrix);GO:0005178(integrin binding);GO:0000904(cell morphogenesis involved in differentiation);GO:0007411(axon guidance);GO:0007528(neuromuscular junction development);GO:0007601(visual perception);GO:0014002(astrocyte development);GO:0014044(Schwann cell development);GO:0031175(neuron projection development);GO:0048677(axon extension involved in regeneration);GO:0050808(synapse organization);GO:0060041(retina development in camera-type eye);GO:0072249(metanephric glomerular visceral epithelial cell development);GO:0072274(metanephric glomerular basement membrane development);GO:0005604(basement membrane);GO:0005605(basal lamina);GO:0005608(laminin-3 complex);GO:0005615(extracellular space);GO:0043083(synaptic cleft);GO:0043256(laminin complex);GO:0045202(synapse);GO:0070062(extracellular exosome);GO:0044267(cellular protein metabolic process);GO:0043687(post-translational protein modification);GO:0031012(extracellular matrix);GO:0005788(endoplasmic reticulum lumen);GO:0030198(extracellular matrix organization);GO:0005198(structural molecule activity);GO:0043260(laminin-11 complex);GO:0043260(laminin-11 complex)","04151(PI3K-Akt signaling pathway);04512(ECM-receptor interaction);04510(Focal adhesion);05200(Pathways in cancer);05222(Small cell lung cancer);05165(Human papillomavirus infection);05146(Amoebiasis);05145(Toxoplasmosis);05145(Toxoplasmosis)","K06243","NA","laminin subunit beta 2 [Source:HGNC Symbol;Acc:HGNC:6487]",{"v":0.244664879096868,"d":"0.24"},{"v":0.493528346686089,"d":"0.49"},{"v":0.495746355279747,"d":"0.50"},{"v":-1.01232592906796,"d":"-1.01"},{"v":0.150293895573152,"d":"0.15"},{"v":0.940427826220425,"d":"0.94"},"down","no"]
["MSTRG.14973","STXBP1","ENST00000637464;ENST00000626416;ENST00000476182;ENST00000637521;ENST00000628768;ENST00000636509;ENST00000496504","GO:0016192(vesicle-mediated transport);GO:0006904(vesicle docking involved in exocytosis);GO:0003723(RNA binding);GO:0006810(transport);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0015031(protein transport);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0005739(mitochondrion);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0070062(extracellular exosome);GO:0000149(SNARE binding);GO:0043234(protein complex);GO:0042802(identical protein binding);GO:0019905(syntaxin binding);GO:0070527(platelet aggregation);GO:0031091(platelet alpha granule);GO:0014047(glutamate secretion);GO:0007269(neurotransmitter secretion);GO:0017075(syntaxin-1 binding);GO:0072659(protein localization to plasma membrane);GO:0002576(platelet degranulation);GO:0016188(synaptic vesicle maturation);GO:0031630(regulation of synaptic vesicle fusion to presynaptic active zone membrane);GO:0019901(protein kinase binding);GO:0019904(protein domain specific binding);GO:0043274(phospholipase binding);GO:0047485(protein N-terminus binding);GO:0003006(developmental process involved in reproduction);GO:0006887(exocytosis);GO:0007274(neuromuscular synaptic transmission);GO:0007412(axon target recognition);GO:0010807(regulation of synaptic vesicle priming);GO:0031333(negative regulation of protein complex assembly);GO:0031338(regulation of vesicle fusion);GO:0032229(negative regulation of synaptic transmission, GABAergic);GO:0032355(response to estradiol);GO:0035542(regulation of SNARE complex assembly);GO:0043306(positive regulation of mast cell degranulation);GO:0043524(negative regulation of neuron apoptotic process);GO:0045921(positive regulation of exocytosis);GO:0045956(positive regulation of calcium ion-dependent exocytosis);GO:0050821(protein stabilization);GO:0060292(long term synaptic depression);GO:0099525(presynaptic dense core vesicle exocytosis);GO:0106022(positive regulation of vesicle docking);GO:1903296(positive regulation of glutamate secretion, neurotransmission);GO:0005634(nucleus);GO:0005856(cytoskeleton);GO:0030424(axon);GO:0043195(terminal bouton);GO:0043209(myelin sheath);GO:0048471(perinuclear region of cytoplasm);GO:0048787(presynaptic active zone membrane);GO:0098793(presynapse);GO:0098794(postsynapse);GO:0098794(postsynapse)","04721(Synaptic vesicle cycle);04721(Synaptic vesicle cycle)","NA","NA","syntaxin binding protein 1 [Source:HGNC Symbol;Acc:HGNC:11444]",{"v":0.248769545815451,"d":"0.25"},{"v":0.128269110300429,"d":"0.13"},{"v":1.93943456248187,"d":"1.94"},{"v":0.955636099418929,"d":"0.96"},{"v":0.150360256015666,"d":"0.15"},{"v":0.940427826220425,"d":"0.94"},"up","no"]
["MSTRG.3641","CHPT1","ENST00000229266;ENST00000549872;ENST00000552215;ENST00000552213;ENST00000550385;ENST00000546873","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0046872(metal ion binding);GO:0016740(transferase activity);GO:0005794(Golgi apparatus);GO:0006629(lipid metabolic process);GO:0016780(phosphotransferase activity, for other substituted phosphate groups);GO:0008654(phospholipid biosynthetic process);GO:0000139(Golgi membrane);GO:0043231(intracellular membrane-bounded organelle);GO:0006656(phosphatidylcholine biosynthetic process);GO:0001558(regulation of cell growth);GO:0019992(diacylglycerol binding);GO:0006663(platelet activating factor biosynthetic process);GO:0006657(CDP-choline pathway);GO:0004142(diacylglycerol cholinephosphotransferase activity);GO:0004142(diacylglycerol cholinephosphotransferase activity)","00564(Glycerophospholipid metabolism);00565(Ether lipid metabolism);00440(Phosphonate and phosphinate metabolism);05231(Choline metabolism in cancer);05231(Choline metabolism in cancer)","K00994","EC:2.7.8.2","choline phosphotransferase 1 [Source:HGNC Symbol;Acc:HGNC:17852]",{"v":2.00207719920053,"d":"2.00"},{"v":3.94887651682212,"d":"3.95"},{"v":0.506999190952598,"d":"0.51"},{"v":-0.979944649847317,"d":"-0.98"},{"v":0.150552045377132,"d":"0.15"},{"v":0.940427826220425,"d":"0.94"},"down","no"]
["MSTRG.1014","IL6R","ENST00000344086;ENST00000368485;ENST00000502679;ENST00000476006;ENST00000515190;ENST00000507256;ENST00000622330","GO:0008284(positive regulation of cell proliferation);GO:0042531(positive regulation of tyrosine phosphorylation of STAT protein);GO:0032755(positive regulation of interleukin-6 production);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0004896(cytokine receptor activity);GO:0004915(interleukin-6 receptor activity);GO:0019981(interleukin-6 binding);GO:0070102(interleukin-6-mediated signaling pathway);GO:0009986(cell surface);GO:0016323(basolateral plasma membrane);GO:0042803(protein homodimerization activity);GO:0050731(positive regulation of peptidyl-tyrosine phosphorylation);GO:0019899(enzyme binding);GO:0032722(positive regulation of chemokine production);GO:0050829(defense response to Gram-negative bacterium);GO:0045669(positive regulation of osteoblast differentiation);GO:0002548(monocyte chemotaxis);GO:0019221(cytokine-mediated signaling pathway);GO:0097191(extrinsic apoptotic signaling pathway);GO:0016324(apical plasma membrane);GO:0048661(positive regulation of smooth muscle cell proliferation);GO:0006953(acute-phase response);GO:0005138(interleukin-6 receptor binding);GO:0002384(hepatic immune response);GO:0002690(positive regulation of leukocyte chemotaxis);GO:0031018(endocrine pancreas development);GO:0005896(interleukin-6 receptor complex);GO:0004897(ciliary neurotrophic factor receptor activity);GO:0070119(ciliary neurotrophic factor binding);GO:0034097(response to cytokine);GO:0070120(ciliary neurotrophic factor-mediated signaling pathway);GO:0070110(ciliary neurotrophic factor receptor complex);GO:0070110(ciliary neurotrophic factor receptor complex)","04630(Jak-STAT signaling pathway);04066(HIF-1 signaling pathway);04151(PI3K-Akt signaling pathway);04060(Cytokine-cytokine receptor interaction);04640(Hematopoietic cell lineage);04659(Th17 cell differentiation);05200(Pathways in cancer);04932(Non-alcoholic fatty liver disease (NAFLD));01521(EGFR tyrosine kinase inhibitor resistance);01521(EGFR tyrosine kinase inhibitor resistance)","K05055","NA","interleukin 6 receptor [Source:HGNC Symbol;Acc:HGNC:6019]",{"v":25.3767175884085,"d":"25.38"},{"v":49.8539002682473,"d":"49.85"},{"v":0.509021710475305,"d":"0.51"},{"v":-0.974200904348487,"d":"-0.97"},{"v":0.150559440207297,"d":"0.15"},{"v":0.940427826220425,"d":"0.94"},"down","no"]
["MSTRG.13681","NSUN5P2","ENST00000388955;ENST00000602348;ENST00000444583;ENST00000457352","NA","NA","NA","NA","NOP2/Sun RNA methyltransferase family member 5 pseudogene 2 [Source:HGNC Symbol;Acc:HGNC:16609]",{"v":2.53735597282609,"d":"2.54"},{"v":1.31336260326087,"d":"1.31"},{"v":1.93195387665694,"d":"1.93"},{"v":0.950060651775859,"d":"0.95"},{"v":0.150576841723062,"d":"0.15"},{"v":0.940427826220425,"d":"0.94"},"up","no"]
["MSTRG.11198","ANAPC13","ENST00000354910;ENST00000510994;ENST00000511751;ENST00000514612;ENST00000508755;ENST00000503439","GO:0005634(nucleus);GO:0016567(protein ubiquitination);GO:0051301(cell division);GO:0005515(protein binding);GO:0007049(cell cycle);GO:0070979(protein K11-linked ubiquitination);GO:0005680(anaphase-promoting complex);GO:0005680(anaphase-promoting complex)","04120(Ubiquitin mediated proteolysis);04110(Cell cycle);04114(Oocyte meiosis);04914(Progesterone-mediated oocyte maturation);04914(Progesterone-mediated oocyte maturation)","K12456","NA","anaphase promoting complex subunit 13 [Source:HGNC Symbol;Acc:HGNC:24540]",{"v":2.82511847392963,"d":"2.83"},{"v":5.6022132462908,"d":"5.60"},{"v":0.504286136519371,"d":"0.50"},{"v":-0.987685530606749,"d":"-0.99"},{"v":0.15058186764062,"d":"0.15"},{"v":0.940427826220425,"d":"0.94"},"down","no"]
["MSTRG.15008","ENDOG","ENST00000372642","GO:0003676(nucleic acid binding);GO:0046872(metal ion binding);GO:0016787(hydrolase activity);GO:0005739(mitochondrion);GO:0005515(protein binding);GO:0006310(DNA recombination);GO:0004519(endonuclease activity);GO:0004518(nuclease activity);GO:0004536(deoxyribonuclease activity);GO:0001701(in utero embryonic development);GO:0006309(apoptotic DNA fragmentation);GO:0007568(aging);GO:0009612(response to mechanical stimulus);GO:0032355(response to estradiol);GO:0034599(cellular response to oxidative stress);GO:0034612(response to tumor necrosis factor);GO:0036475(neuron death in response to oxidative stress);GO:0043065(positive regulation of apoptotic process);GO:0046677(response to antibiotic);GO:0071277(cellular response to calcium ion);GO:0071333(cellular response to glucose stimulus);GO:0071456(cellular response to hypoxia);GO:1901300(positive regulation of hydrogen peroxide-mediated programmed cell death);GO:1902512(positive regulation of apoptotic DNA fragmentation);GO:0005634(nucleus);GO:0005829(cytosol);GO:0043204(perikaryon)","04210(Apoptosis)","K01173","NA","endonuclease G [Source:HGNC Symbol;Acc:HGNC:3346]",{"v":0.55861,"d":"0.56"},{"v":1.162795,"d":"1.16"},{"v":0.480402822509557,"d":"0.48"},{"v":-1.05768346755618,"d":"-1.06"},{"v":0.150715023016968,"d":"0.15"},{"v":0.940427826220425,"d":"0.94"},"down","no"]
["ENSG00000171202","TMEM126A","ENST00000304511;ENST00000528105;ENST00000525353;ENST00000531366;ENST00000528531;ENST00000532180","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005743(mitochondrial inner membrane);GO:0005739(mitochondrion);GO:0003674(molecular_function);GO:0021554(optic nerve development);GO:0021554(optic nerve development)","NA","NA","NA","transmembrane protein 126A [Source:HGNC Symbol;Acc:HGNC:25382]",{"v":0.658214886714727,"d":"0.66"},{"v":1.38480913697219,"d":"1.38"},{"v":0.475310906854556,"d":"0.48"},{"v":-1.07305658766234,"d":"-1.07"},{"v":0.150715023016968,"d":"0.15"},{"v":0.940427826220425,"d":"0.94"},"down","no"]
["ENSG00000038945","MSR1","ENST00000381998;ENST00000262101;ENST00000350896","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005515(protein binding);GO:0005581(collagen trimer);GO:0005044(scavenger receptor activity);GO:0006898(receptor-mediated endocytosis);GO:0005886(plasma membrane);GO:0006897(endocytosis);GO:0005887(integral component of plasma membrane);GO:0030666(endocytic vesicle membrane);GO:0010744(positive regulation of macrophage derived foam cell differentiation);GO:0006911(phagocytosis, engulfment);GO:0097242(amyloid-beta clearance);GO:0030169(low-density lipoprotein particle binding);GO:0034362(low-density lipoprotein particle);GO:0010886(positive regulation of cholesterol storage);GO:0030301(cholesterol transport);GO:0010629(negative regulation of gene expression);GO:0034381(plasma lipoprotein particle clearance);GO:0001540(amyloid-beta binding);GO:0042953(lipoprotein transport);GO:0071407(cellular response to organic cyclic compound);GO:0005829(cytosol);GO:0031410(cytoplasmic vesicle);GO:0031410(cytoplasmic vesicle)","04145(Phagosome);04145(Phagosome)","K06558","NA","macrophage scavenger receptor 1 [Source:HGNC Symbol;Acc:HGNC:7376]",{"v":0.27571532718894,"d":"0.28"},{"v":0.553418959805427,"d":"0.55"},{"v":0.498203616453395,"d":"0.50"},{"v":-1.00519260076658,"d":"-1.01"},{"v":0.150718619197352,"d":"0.15"},{"v":0.940427826220425,"d":"0.94"},"down","no"]
["MSTRG.12548","HRH2","MSTRG.12548.4;ENST00000377291;ENST00000624694;MSTRG.12548.2;MSTRG.12548.3;ENST00000231683;ENST00000636584","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0004930(G-protein coupled receptor activity);GO:0007186(G-protein coupled receptor signaling pathway);GO:0005886(plasma membrane);GO:0004871(signal transducer activity);GO:0007165(signal transduction);GO:0001696(gastric acid secretion);GO:0004969(histamine receptor activity);GO:0045907(positive regulation of vasoconstriction);GO:0005887(integral component of plasma membrane);GO:0006955(immune response);GO:0007187(G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger);GO:0001697(histamine-induced gastric acid secretion);GO:0001698(gastrin-induced gastric acid secretion);GO:0003382(epithelial cell morphogenesis);GO:0007613(memory);GO:0008542(visual learning);GO:0048167(regulation of synaptic plasticity);GO:0048565(digestive tract development);GO:0048732(gland development);GO:1901998(toxin transport);GO:1901998(toxin transport)","04020(Calcium signaling pathway);04080(Neuroactive ligand-receptor interaction);04971(Gastric acid secretion);04971(Gastric acid secretion)","K04150","NA","histamine receptor H2 [Source:HGNC Symbol;Acc:HGNC:5183]",{"v":12.7464766956663,"d":"12.75"},{"v":25.0206448811881,"d":"25.02"},{"v":0.509438376036814,"d":"0.51"},{"v":-0.973020452839788,"d":"-0.97"},{"v":0.151068306136785,"d":"0.15"},{"v":0.940427826220425,"d":"0.94"},"down","no"]
["MSTRG.13391","SYNE1","MSTRG.13391.7;ENST00000367255;ENST00000347037;ENST00000478916;ENST00000423061;ENST00000367257;ENST00000367253;ENST00000537033;ENST00000341594;ENST00000466159;ENST00000468937;ENST00000367251;ENST00000490866;ENST00000454018;ENST00000354674;ENST00000448038;ENST00000472563;ENST00000536990;ENST00000367248;ENST00000539504;ENST00000495090;ENST00000540663;ENST00000537750;ENST00000471834;ENST00000489156;ENST00000461872;ENST00000460912","GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005654(nucleoplasm);GO:0031965(nuclear membrane);GO:0051015(actin filament binding);GO:0005794(Golgi apparatus);GO:0003779(actin binding);GO:0042803(protein homodimerization activity);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0034993(LINC complex);GO:0045211(postsynaptic membrane);GO:0030154(cell differentiation);GO:0007283(spermatogenesis);GO:0090286(cytoskeletal anchoring at nuclear membrane);GO:0005635(nuclear envelope);GO:0019899(enzyme binding);GO:0005730(nucleolus);GO:0007030(Golgi organization);GO:0030017(sarcomere);GO:0006997(nucleus organization);GO:0005521(lamin binding);GO:0090292(nuclear matrix anchoring at nuclear membrane);GO:0042692(muscle cell differentiation);GO:0005640(nuclear outer membrane);GO:0000932(P-body);GO:0008092(cytoskeletal protein binding);GO:0008092(cytoskeletal protein binding)","NA","NA","NA","spectrin repeat containing nuclear envelope protein 1 [Source:HGNC Symbol;Acc:HGNC:17089]",{"v":2.62050421751755,"d":"2.62"},{"v":1.3838459718731,"d":"1.38"},{"v":1.89363864966169,"d":"1.89"},{"v":0.921161057269987,"d":"0.92"},{"v":0.151110994039993,"d":"0.15"},{"v":0.940427826220425,"d":"0.94"},"up","no"]
["MSTRG.2391","TIMM10","ENST00000257245;ENST00000525158","GO:0006810(transport);GO:0016020(membrane);GO:0008565(protein transporter activity);GO:0015031(protein transport);GO:0046872(metal ion binding);GO:0005739(mitochondrion);GO:0005743(mitochondrial inner membrane);GO:0008270(zinc ion binding);GO:0005515(protein binding);GO:0007605(sensory perception of sound);GO:0042803(protein homodimerization activity);GO:0006626(protein targeting to mitochondrion);GO:0005758(mitochondrial intermembrane space);GO:0051087(chaperone binding);GO:0072321(chaperone-mediated protein transport);GO:0005744(mitochondrial inner membrane presequence translocase complex);GO:0005215(transporter activity);GO:0045039(protein import into mitochondrial inner membrane);GO:0042719(mitochondrial intermembrane space protein transporter complex);GO:0042719(mitochondrial intermembrane space protein transporter complex)","NA","NA","NA","translocase of inner mitochondrial membrane 10 [Source:HGNC Symbol;Acc:HGNC:11814]",{"v":7.3720928957529,"d":"7.37"},{"v":3.84559223938224,"d":"3.85"},{"v":1.91702407245786,"d":"1.92"},{"v":0.938868453332371,"d":"0.94"},{"v":0.151217849364427,"d":"0.15"},{"v":0.940427826220425,"d":"0.94"},"up","no"]
["ENSG00000137710","RDX","ENST00000343115;ENST00000532461;ENST00000529774;ENST00000530085","GO:0003723(RNA binding);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0003779(actin binding);GO:0005886(plasma membrane);GO:0042803(protein homodimerization activity);GO:0051693(actin filament capping);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0008092(cytoskeletal protein binding);GO:0005615(extracellular space);GO:0005925(focal adhesion);GO:0045296(cadherin binding);GO:0030027(lamellipodium);GO:0030175(filopodium);GO:0070062(extracellular exosome);GO:0010628(positive regulation of gene expression);GO:0071944(cell periphery);GO:0032154(cleavage furrow);GO:0030335(positive regulation of cell migration);GO:0005902(microvillus);GO:0008360(regulation of cell shape);GO:0016324(apical plasma membrane);GO:0061028(establishment of endothelial barrier);GO:0030864(cortical actin cytoskeleton);GO:1900087(positive regulation of G1/S transition of mitotic cell cycle);GO:0043087(regulation of GTPase activity);GO:0008361(regulation of cell size);GO:0090002(establishment of protein localization to plasma membrane);GO:0045184(establishment of protein localization);GO:0051018(protein kinase A binding);GO:0051117(ATPase binding);GO:0097067(cellular response to thyroid hormone stimulus);GO:0010737(protein kinase A signaling);GO:1902115(regulation of organelle assembly);GO:1902966(positive regulation of protein localization to early endosome);GO:1903364(positive regulation of cellular protein catabolic process);GO:2000643(positive regulation of early endosome to late endosome transport);GO:0032231(regulation of actin filament bundle assembly);GO:0032487(regulation of Rap protein signal transduction);GO:0034111(negative regulation of homotypic cell-cell adhesion);GO:0034260(negative regulation of GTPase activity);GO:0045792(negative regulation of cell size);GO:1900027(regulation of ruffle assembly);GO:1903392(negative regulation of adherens junction organization);GO:0019904(protein domain specific binding);GO:0030033(microvillus assembly);GO:0036120(cellular response to platelet-derived growth factor stimulus);GO:0045176(apical protein localization);GO:0051016(barbed-end actin filament capping);GO:0001726(ruffle);GO:0005913(cell-cell adherens junction);GO:0030315(T-tubule);GO:0030496(midbody);GO:0032420(stereocilium);GO:0043209(myelin sheath);GO:0045177(apical part of cell);GO:0051286(cell tip);GO:0051286(cell tip)","04530(Tight junction);04810(Regulation of actin cytoskeleton);05206(MicroRNAs in cancer);05205(Proteoglycans in cancer);05205(Proteoglycans in cancer)","K05762","NA","radixin [Source:HGNC Symbol;Acc:HGNC:9944]",{"v":0.537984789138349,"d":"0.54"},{"v":1.0679584695085,"d":"1.07"},{"v":0.503750664935447,"d":"0.50"},{"v":-0.989218256932239,"d":"-0.99"},{"v":0.151399001441315,"d":"0.15"},{"v":0.940427826220425,"d":"0.94"},"down","no"]
["MSTRG.6018","ATP6V0D1","ENST00000290949;ENST00000567170;ENST00000568620;ENST00000564191;ENST00000563305;ENST00000561658;ENST00000566322;ENST00000540149;ENST00000563064;ENST00000561852;ENST00000565835;ENST00000564615;ENST00000568101;ENST00000426604;ENST00000568298;ENST00000567694;ENST00000564788","GO:0006810(transport);GO:0016020(membrane);GO:0005765(lysosomal membrane);GO:0006811(ion transport);GO:0006879(cellular iron ion homeostasis);GO:0015078(hydrogen ion transmembrane transporter activity);GO:0015991(ATP hydrolysis coupled proton transport);GO:0015992(proton transport);GO:0033179(proton-transporting V-type ATPase, V0 domain);GO:0005813(centrosome);GO:0005515(protein binding);GO:0060271(cilium assembly);GO:0070062(extracellular exosome);GO:0034220(ion transmembrane transport);GO:0030030(cell projection organization);GO:0010008(endosome membrane);GO:0005769(early endosome);GO:0030670(phagocytic vesicle membrane);GO:0036498(IRE1-mediated unfolded protein response);GO:0008286(insulin receptor signaling pathway);GO:0016241(regulation of macroautophagy);GO:0033572(transferrin transport);GO:0090383(phagosome acidification);GO:0036295(cellular response to increased oxygen levels);GO:0008553(hydrogen-exporting ATPase activity, phosphorylative mechanism);GO:0046961(proton-transporting ATPase activity, rotational mechanism);GO:0032403(protein complex binding);GO:0007034(vacuolar transport);GO:0007035(vacuolar acidification);GO:0007420(brain development);GO:0008021(synaptic vesicle);GO:0016324(apical plasma membrane);GO:0016471(vacuolar proton-transporting V-type ATPase complex);GO:0043005(neuron projection);GO:0043234(protein complex);GO:0043679(axon terminus);GO:0043679(axon terminus)","00190(Oxidative phosphorylation);04145(Phagosome);04142(Lysosome);04966(Collecting duct acid secretion);04721(Synaptic vesicle cycle);05203(Viral carcinogenesis);05323(Rheumatoid arthritis);05110(Vibrio cholerae infection);05120(Epithelial cell signaling in Helicobacter pylori infection);05152(Tuberculosis);05152(Tuberculosis)","K02146","NA","ATPase H+ transporting V0 subunit d1 [Source:HGNC Symbol;Acc:HGNC:13724]",{"v":6.8657837174866,"d":"6.87"},{"v":13.4838967110326,"d":"13.48"},{"v":0.509183944717478,"d":"0.51"},{"v":-0.973741165125017,"d":"-0.97"},{"v":0.151435406574018,"d":"0.15"},{"v":0.940427826220425,"d":"0.94"},"down","no"]
["ENSG00000122484","RPAP2","ENST00000610020;ENST00000477322","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0005730(nucleolus);GO:0005829(cytosol);GO:0016787(hydrolase activity);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0004721(phosphoprotein phosphatase activity);GO:0005515(protein binding);GO:0005654(nucleoplasm);GO:0042795(snRNA transcription from RNA polymerase II promoter);GO:0004722(protein serine/threonine phosphatase activity);GO:0008420(CTD phosphatase activity);GO:0016591(DNA-directed RNA polymerase II, holoenzyme);GO:0009301(snRNA transcription);GO:0070940(dephosphorylation of RNA polymerase II C-terminal domain);GO:0070940(dephosphorylation of RNA polymerase II C-terminal domain)","NA","NA","NA","RNA polymerase II associated protein 2 [Source:HGNC Symbol;Acc:HGNC:25791]",{"v":0.727700293606347,"d":"0.73"},{"v":0.382109514992416,"d":"0.38"},{"v":1.90442861288285,"d":"1.90"},{"v":0.929358209786188,"d":"0.93"},{"v":0.151506032078534,"d":"0.15"},{"v":0.940427826220425,"d":"0.94"},"up","no"]
["MSTRG.5784","ATXN2L","ENST00000566946;ENST00000562583;ENST00000336783;ENST00000340394;ENST00000561732;ENST00000562867;ENST00000565845;ENST00000564304;ENST00000564656;ENST00000395547;ENST00000570200;ENST00000564284;ENST00000563314;ENST00000382686;ENST00000325215;ENST00000564035;ENST00000561539;ENST00000570284;ENST00000566080;MSTRG.5784.10;ENST00000562686;ENST00000569318","GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016607(nuclear speck);GO:0016020(membrane);GO:0005829(cytosol);GO:0005515(protein binding);GO:0045296(cadherin binding);GO:0010494(cytoplasmic stress granule);GO:0034063(stress granule assembly);GO:0010603(regulation of cytoplasmic mRNA processing body assembly);GO:0016021(integral component of membrane);GO:0016021(integral component of membrane)","NA","NA","NA","ataxin 2 like [Source:HGNC Symbol;Acc:HGNC:31326]",{"v":12.8403122163491,"d":"12.84"},{"v":6.77770494975415,"d":"6.78"},{"v":1.89449265076298,"d":"1.89"},{"v":0.921811543262631,"d":"0.92"},{"v":0.151507930495306,"d":"0.15"},{"v":0.940427826220425,"d":"0.94"},"up","no"]
["ENSG00000182197","EXT1","ENST00000378204;ENST00000437196","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0046872(metal ion binding);GO:0016740(transferase activity);GO:0016757(transferase activity, transferring glycosyl groups);GO:0005794(Golgi apparatus);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0000139(Golgi membrane);GO:0006486(protein glycosylation);GO:0015020(glucuronosyltransferase activity);GO:0015012(heparan sulfate proteoglycan biosynthetic process);GO:0030176(integral component of endoplasmic reticulum membrane);GO:0042803(protein homodimerization activity);GO:0046982(protein heterodimerization activity);GO:0007165(signal transduction);GO:0001501(skeletal system development);GO:0006024(glycosaminoglycan biosynthetic process);GO:0001503(ossification);GO:0008375(acetylglucosaminyltransferase activity);GO:0042328(heparan sulfate N-acetylglucosaminyltransferase activity);GO:0050508(glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity);GO:0050509(N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity);GO:0007369(gastrulation);GO:0007411(axon guidance);GO:0007420(brain development);GO:0007492(endoderm development);GO:0007498(mesoderm development);GO:0015014(heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process);GO:0021772(olfactory bulb development);GO:0033692(cellular polysaccharide biosynthetic process);GO:0072498(embryonic skeletal joint development);GO:0072498(embryonic skeletal joint development)","00534(Glycosaminoglycan biosynthesis - heparan sulfate / heparin);00534(Glycosaminoglycan biosynthesis - heparan sulfate / heparin)","K02366","EC:2.4.1.224;EC:2.4.1.225","exostosin glycosyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:3512]",{"v":0.688757589189189,"d":"0.69"},{"v":1.36093404804805,"d":"1.36"},{"v":0.506091819935768,"d":"0.51"},{"v":-0.98252893892341,"d":"-0.98"},{"v":0.151721101694421,"d":"0.15"},{"v":0.940427826220425,"d":"0.94"},"down","no"]
["ENSG00000142632","ARHGEF19","ENST00000270747;ENST00000449495;ENST00000441785;ENST00000478117;ENST00000471928","GO:0005089(Rho guanyl-nucleotide exchange factor activity);GO:0035023(regulation of Rho protein signal transduction);GO:0005515(protein binding);GO:0005096(GTPase activator activity);GO:0005085(guanyl-nucleotide exchange factor activity);GO:0005829(cytosol);GO:0051056(regulation of small GTPase mediated signal transduction);GO:0060071(Wnt signaling pathway, planar cell polarity pathway);GO:0043065(positive regulation of apoptotic process);GO:0032956(regulation of actin cytoskeleton organization);GO:0042060(wound healing);GO:0043547(positive regulation of GTPase activity);GO:0043547(positive regulation of GTPase activity)","NA","NA","NA","Rho guanine nucleotide exchange factor 19 [Source:HGNC Symbol;Acc:HGNC:26604]",{"v":0.913569933511349,"d":"0.91"},{"v":0.474082241388518,"d":"0.47"},{"v":1.92702837979258,"d":"1.93"},{"v":0.946377818693582,"d":"0.95"},{"v":0.15180131688027,"d":"0.15"},{"v":0.940427826220425,"d":"0.94"},"up","no"]
["ENSG00000280077","AL353763.2","ENST00000623489","NA","NA","NA","NA",null,{"v":1.806589,"d":"1.81"},{"v":0.936772,"d":"0.94"},{"v":1.92852583125883,"d":"1.93"},{"v":0.947498469990236,"d":"0.95"},{"v":0.15180131688027,"d":"0.15"},{"v":0.940427826220425,"d":"0.94"},"up","no"]
["ENSG00000187607","ZNF286A","ENST00000583566;ENST00000481540;ENST00000580393;ENST00000395893;ENST00000464847;ENST00000395894;ENST00000583347;ENST00000421016;ENST00000579694;ENST00000585207;ENST00000579516;ENST00000585194","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0005622(intracellular);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016021(integral component of membrane)","NA","NA","NA","zinc finger protein 286A [Source:HGNC Symbol;Acc:HGNC:13501]",{"v":0.275992611489488,"d":"0.28"},{"v":0.138989252442997,"d":"0.14"},{"v":1.98571189238304,"d":"1.99"},{"v":0.989656316933622,"d":"0.99"},{"v":0.151873872824197,"d":"0.15"},{"v":0.940427826220425,"d":"0.94"},"up","no"]
["ENSG00000276116","FUT8-AS1","ENST00000621019","NA","NA","NA","NA","FUT8 antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:44294]",{"v":0.402835,"d":"0.40"},{"v":0.845086,"d":"0.85"},{"v":0.476679296544967,"d":"0.48"},{"v":-1.06890912821805,"d":"-1.07"},{"v":0.151876602916968,"d":"0.15"},{"v":0.940427826220425,"d":"0.94"},"down","no"]
["MSTRG.9211","AC107075.1","ENST00000613695","NA","NA","NA","NA",null,{"v":1.960862,"d":"1.96"},{"v":4.10082,"d":"4.10"},{"v":0.478163391711902,"d":"0.48"},{"v":-1.0644244136404,"d":"-1.06"},{"v":0.151876602916968,"d":"0.15"},{"v":0.940427826220425,"d":"0.94"},"down","no"]
["ENSG00000221994","ZNF630","ENST00000442455;ENST00000428686","GO:0003676(nucleic acid binding);GO:0006355(regulation of transcription, DNA-templated);GO:0005622(intracellular);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding)","NA","NA","NA","zinc finger protein 630 [Source:HGNC Symbol;Acc:HGNC:28855]",{"v":0.165000886289445,"d":"0.17"},{"v":0.348794305495103,"d":"0.35"},{"v":0.47306072286711,"d":"0.47"},{"v":-1.07990271268322,"d":"-1.08"},{"v":0.151876602916968,"d":"0.15"},{"v":0.940427826220425,"d":"0.94"},"down","no"]
["MSTRG.7256","ST6GALNAC2;AC015802.6","ENST00000225276;ENST00000640006;ENST00000592979;ENST00000592508;ENST00000588920;ENST00000588005;ENST00000585736;ENST00000585390;ENST00000588120;ENST00000586520","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016740(transferase activity);GO:0008373(sialyltransferase activity);GO:0016757(transferase activity, transferring glycosyl groups);GO:0006486(protein glycosylation);GO:0097503(sialylation);GO:0005794(Golgi apparatus);GO:0000139(Golgi membrane);GO:0016266(O-glycan processing);GO:0009311(oligosaccharide metabolic process);GO:0018279(protein N-linked glycosylation via asparagine);GO:0001665(alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity);GO:0001665(alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity)","NA","NA","NA","ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 [Source:HGNC Symbol;Acc:HGNC:10867]",{"v":1.47183578406986,"d":"1.47"},{"v":2.89543866618153,"d":"2.90"},{"v":0.508329118230261,"d":"0.51"},{"v":-0.976165220931229,"d":"-0.98"},{"v":0.151924812570416,"d":"0.15"},{"v":0.940427826220425,"d":"0.94"},"down","no"]
["ENSG00000135736","CCDC102A","ENST00000258214","GO:0003774(motor activity);GO:0016459(myosin complex)","NA","NA","NA","coiled-coil domain containing 102A [Source:HGNC Symbol;Acc:HGNC:28097]",{"v":2.38519133075136,"d":"2.39"},{"v":1.24926660534469,"d":"1.25"},{"v":1.9092732652477,"d":"1.91"},{"v":0.933023603634261,"d":"0.93"},{"v":0.15193002391827,"d":"0.15"},{"v":0.940427826220425,"d":"0.94"},"up","no"]
["ENSG00000274070","CASTOR2","ENST00000616305;ENST00000622472","GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005515(protein binding);GO:1904262(negative regulation of TORC1 signaling);GO:0061700(GATOR2 complex);GO:0042802(identical protein binding);GO:0042802(identical protein binding)","NA","NA","NA","cytosolic arginine sensor for mTORC1 subunit 2 [Source:HGNC Symbol;Acc:HGNC:37073]",{"v":0.914955820983125,"d":"0.91"},{"v":1.86111933455613,"d":"1.86"},{"v":0.49161588082762,"d":"0.49"},{"v":-1.02439657457713,"d":"-1.02"},{"v":0.152025994831769,"d":"0.15"},{"v":0.940427826220425,"d":"0.94"},"down","no"]
["ENSG00000170631","ZNF16","ENST00000529378;ENST00000527427;ENST00000532351;ENST00000532811;ENST00000527512;ENST00000394909;ENST00000527811;ENST00000611477;ENST00000276816","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0005730(nucleolus);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0051301(cell division);GO:0005515(protein binding);GO:0007049(cell cycle);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0008284(positive regulation of cell proliferation);GO:0043066(negative regulation of apoptotic process);GO:0051781(positive regulation of cell division);GO:0045648(positive regulation of erythrocyte differentiation);GO:0033674(positive regulation of kinase activity);GO:0045654(positive regulation of megakaryocyte differentiation);GO:0072707(cellular response to sodium dodecyl sulfate);GO:1901989(positive regulation of cell cycle phase transition);GO:1901989(positive regulation of cell cycle phase transition)","NA","NA","NA","zinc finger protein 16 [Source:HGNC Symbol;Acc:HGNC:12947]",{"v":0.14189915333206,"d":"0.14"},{"v":0.295138012793584,"d":"0.30"},{"v":0.48078914670779,"d":"0.48"},{"v":-1.05652376574255,"d":"-1.06"},{"v":0.152063156769544,"d":"0.15"},{"v":0.940427826220425,"d":"0.94"},"down","no"]
["MSTRG.7420","IMPA2","ENST00000269159;ENST00000588167;ENST00000383376;ENST00000625802;ENST00000586230;ENST00000590107;ENST00000589238;ENST00000588752;ENST00000588863;ENST00000589374;ENST00000590138","GO:0046872(metal ion binding);GO:0016787(hydrolase activity);GO:0046854(phosphatidylinositol phosphorylation);GO:0008934(inositol monophosphate 1-phosphatase activity);GO:0052832(inositol monophosphate 3-phosphatase activity);GO:0052833(inositol monophosphate 4-phosphatase activity);GO:0052834(inositol monophosphate phosphatase activity);GO:0006021(inositol biosynthetic process);GO:0046855(inositol phosphate dephosphorylation);GO:0005515(protein binding);GO:0005829(cytosol);GO:0007165(signal transduction);GO:0005737(cytoplasm);GO:0006796(phosphate-containing compound metabolic process);GO:0042803(protein homodimerization activity);GO:0006020(inositol metabolic process);GO:0043647(inositol phosphate metabolic process);GO:0043647(inositol phosphate metabolic process)","00562(Inositol phosphate metabolism);04070(Phosphatidylinositol signaling system);04070(Phosphatidylinositol signaling system)","K01092","EC:3.1.3.25","inositol monophosphatase 2 [Source:HGNC Symbol;Acc:HGNC:6051]",{"v":8.22314070117647,"d":"8.22"},{"v":16.1380611273203,"d":"16.14"},{"v":0.509549482822037,"d":"0.51"},{"v":-0.972705840242021,"d":"-0.97"},{"v":0.152087273427903,"d":"0.15"},{"v":0.940427826220425,"d":"0.94"},"down","no"]
["MSTRG.2049","ADAM8","ENST00000485491;ENST00000415217;MSTRG.2049.2;ENST00000445355;ENST00000559180;ENST00000559018;ENST00000463298;ENST00000537099;ENST00000468964;ENST00000560135;ENST00000486609","GO:0050714(positive regulation of protein secretion);GO:0051897(positive regulation of protein kinase B signaling);GO:0005737(cytoplasm);GO:0002675(positive regulation of acute inflammatory response);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0046872(metal ion binding);GO:0016787(hydrolase activity);GO:0008233(peptidase activity);GO:0006508(proteolysis);GO:0004222(metalloendopeptidase activity);GO:0008237(metallopeptidase activity);GO:0004252(serine-type endopeptidase activity);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0043312(neutrophil degranulation);GO:0035579(specific granule membrane);GO:0070821(tertiary granule membrane);GO:0009986(cell surface);GO:0051092(positive regulation of NF-kappaB transcription factor activity);GO:0006954(inflammatory response);GO:0022617(extracellular matrix disassembly);GO:0071456(cellular response to hypoxia);GO:0001525(angiogenesis);GO:0005509(calcium ion binding);GO:0101003(ficolin-1-rich granule membrane);GO:0051044(positive regulation of membrane protein ectodomain proteolysis);GO:0043524(negative regulation of neuron apoptotic process);GO:0005887(integral component of plasma membrane);GO:0000902(cell morphogenesis);GO:0008270(zinc ion binding);GO:0033089(positive regulation of T cell differentiation in thymus);GO:2000309(positive regulation of tumor necrosis factor (ligand) superfamily member 11 production);GO:0050839(cell adhesion molecule binding);GO:0045785(positive regulation of cell adhesion);GO:0070245(positive regulation of thymocyte apoptotic process);GO:0043621(protein self-association);GO:0002523(leukocyte migration involved in inflammatory response);GO:0002102(podosome);GO:0071065(alpha9-beta1 integrin-vascular cell adhesion molecule-1 complex);GO:0002693(positive regulation of cellular extravasation);GO:0010954(positive regulation of protein processing);GO:0016337(single organismal cell-cell adhesion);GO:0022407(regulation of cell-cell adhesion);GO:0035419(activation of MAPK activity involved in innate immune response);GO:0045780(positive regulation of bone resorption);GO:0048247(lymphocyte chemotaxis);GO:0050729(positive regulation of inflammatory response);GO:2000391(positive regulation of neutrophil extravasation);GO:2000406(positive regulation of T cell migration);GO:2000415(positive regulation of fibronectin-dependent thymocyte migration);GO:2000418(positive regulation of eosinophil migration);GO:0032010(phagolysosome);GO:0032127(dense core granule membrane);GO:0042581(specific granule);GO:0070820(tertiary granule);GO:0071133(alpha9-beta1 integrin-ADAM8 complex);GO:0071133(alpha9-beta1 integrin-ADAM8 complex)","NA","NA","NA","ADAM metallopeptidase domain 8 [Source:HGNC Symbol;Acc:HGNC:215]",{"v":23.2537296539345,"d":"23.25"},{"v":45.5750777862659,"d":"45.58"},{"v":0.510229072191338,"d":"0.51"},{"v":-0.970782990711111,"d":"-0.97"},{"v":0.152129020745494,"d":"0.15"},{"v":0.940427826220425,"d":"0.94"},"down","no"]
["MSTRG.12908","HLA-DQB1;HLA-DQB2","MSTRG.12908.7;ENST00000443574;ENST00000434651;ENST00000435145;ENST00000374943;ENST00000487676;ENST00000399079","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0006955(immune response);GO:0002376(immune system process);GO:0002504(antigen processing and presentation of peptide or polysaccharide antigen via MHC class II);GO:0019882(antigen processing and presentation);GO:0042613(MHC class II protein complex);GO:0005794(Golgi apparatus);GO:0005765(lysosomal membrane);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005886(plasma membrane);GO:0005764(lysosome);GO:0005768(endosome);GO:0050852(T cell receptor signaling pathway);GO:0010008(endosome membrane);GO:0019886(antigen processing and presentation of exogenous peptide antigen via MHC class II);GO:0032588(trans-Golgi network membrane);GO:0000139(Golgi membrane);GO:0030666(endocytic vesicle membrane);GO:0060333(interferon-gamma-mediated signaling pathway);GO:0012507(ER to Golgi transport vesicle membrane);GO:0031295(T cell costimulation);GO:0071556(integral component of lumenal side of endoplasmic reticulum membrane);GO:0030669(clathrin-coated endocytic vesicle membrane);GO:0030658(transport vesicle membrane);GO:0032395(MHC class II receptor activity);GO:0042613(MHC class II protein complex)","04514(Cell adhesion molecules (CAMs));04145(Phagosome);04640(Hematopoietic cell lineage);04612(Antigen processing and presentation);04658(Th1 and Th2 cell differentiation);04659(Th17 cell differentiation);04672(Intestinal immune network for IgA production);05310(Asthma);05322(Systemic lupus erythematosus);05323(Rheumatoid arthritis);05320(Autoimmune thyroid disease);05321(Inflammatiory bowel disease (IBD));05330(Allograft rejection);05332(Graft-versus-host disease);05416(Viral myocarditis);04940(Type I diabetes mellitus);05150(Staphylococcus aureus infection);05152(Tuberculosis);05166(HTLV-I infection);05164(Influenza A);05168(Herpes simplex infection);05169(Epstein-Barr virus infection);05145(Toxoplasmosis);05140(Leishmaniasis);05140(Leishmaniasis)","K06752","NA","major histocompatibility complex, class II, DQ beta 1 [Source:HGNC Symbol;Acc:HGNC:4944];major histocompatibility complex, class II, DQ beta 2 [Source:HGNC Symbol;Acc:HGNC:4945]",{"v":0.401396395701096,"d":"0.40"},{"v":0.805997167916907,"d":"0.81"},{"v":0.498012166393217,"d":"0.50"},{"v":-1.00574710725112,"d":"-1.01"},{"v":0.152194926189891,"d":"0.15"},{"v":0.940427826220425,"d":"0.94"},"down","no"]
["MSTRG.1420","SRP9","ENST00000304786;ENST00000366839;ENST00000619790;ENST00000366838;ENST00000626563","GO:0003723(RNA binding);GO:0005737(cytoplasm);GO:0030529(intracellular ribonucleoprotein complex);GO:0005515(protein binding);GO:0008312(7S RNA binding);GO:0006614(SRP-dependent cotranslational protein targeting to membrane);GO:0048500(signal recognition particle);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0006616(SRP-dependent cotranslational protein targeting to membrane, translocation);GO:0005786(signal recognition particle, endoplasmic reticulum targeting);GO:0005047(signal recognition particle binding);GO:0005785(signal recognition particle receptor complex);GO:0045900(negative regulation of translational elongation);GO:0045900(negative regulation of translational elongation)","03060(Protein export);03060(Protein export)","K03109","NA","signal recognition particle 9 [Source:HGNC Symbol;Acc:HGNC:11304]",{"v":9.65358046354167,"d":"9.65"},{"v":18.9663042013889,"d":"18.97"},{"v":0.50898584990716,"d":"0.51"},{"v":-0.974302545762285,"d":"-0.97"},{"v":0.1522531678358,"d":"0.15"},{"v":0.940427826220425,"d":"0.94"},"down","no"]
["MSTRG.8845","DOK1","ENST00000464613;ENST00000233668;ENST00000340004;ENST00000482206;ENST00000489958;ENST00000485132;ENST00000474924;ENST00000480318;ENST00000409429;ENST00000488613","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005515(protein binding);GO:0048471(perinuclear region of cytoplasm);GO:0005158(insulin receptor binding);GO:0007165(signal transduction);GO:0007166(cell surface receptor signaling pathway);GO:0007411(axon guidance);GO:0007169(transmembrane receptor protein tyrosine kinase signaling pathway);GO:0045742(positive regulation of epidermal growth factor receptor signaling pathway);GO:0005057(signal transducer activity, downstream of receptor);GO:0007265(Ras protein signal transduction);GO:0035556(intracellular signal transduction);GO:0035556(intracellular signal transduction)","05162(Measles);05162(Measles)","K14752","NA","docking protein 1 [Source:HGNC Symbol;Acc:HGNC:2990]",{"v":3.34701514693342,"d":"3.35"},{"v":6.58097126500492,"d":"6.58"},{"v":0.508589843680303,"d":"0.51"},{"v":-0.975425442569058,"d":"-0.98"},{"v":0.152380044302617,"d":"0.15"},{"v":0.940427826220425,"d":"0.94"},"down","no"]
["ENSG00000242193","AL359075.1","ENST00000476232;ENST00000462729;ENST00000512906;ENST00000481349","NA","NA","NA","NA",null,{"v":0.333621886421091,"d":"0.33"},{"v":0.66831598808234,"d":"0.67"},{"v":0.49919782314109,"d":"0.50"},{"v":-1.00231645185387,"d":"-1.00"},{"v":0.152445999797173,"d":"0.15"},{"v":0.940427826220425,"d":"0.94"},"down","no"]
["MSTRG.13131","TMEM30A","ENST00000230461;ENST00000475111;ENST00000370050;ENST00000518161","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005794(Golgi apparatus);GO:0005783(endoplasmic reticulum);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0006869(lipid transport);GO:0031410(cytoplasmic vesicle);GO:0015914(phospholipid transport);GO:0043312(neutrophil degranulation);GO:0035579(specific granule membrane);GO:0016324(apical plasma membrane);GO:0035577(azurophil granule membrane);GO:0006855(drug transmembrane transport);GO:0045332(phospholipid translocation);GO:0030658(transport vesicle membrane);GO:0036010(protein localization to endosome);GO:0070863(positive regulation of protein exit from endoplasmic reticulum);GO:0010976(positive regulation of neuron projection development);GO:0010976(positive regulation of neuron projection development)","NA","NA","NA","transmembrane protein 30A [Source:HGNC Symbol;Acc:HGNC:16667]",{"v":5.10621293402303,"d":"5.11"},{"v":10.0114221536209,"d":"10.01"},{"v":0.51003871934181,"d":"0.51"},{"v":-0.971321322152127,"d":"-0.97"},{"v":0.152558979114307,"d":"0.15"},{"v":0.940427826220425,"d":"0.94"},"down","no"]
["ENSG00000182183","FAM159A","ENST00000517870;ENST00000424164;ENST00000440303;ENST00000401050","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016021(integral component of membrane)","NA","NA","NA","family with sequence similarity 159 member A [Source:HGNC Symbol;Acc:HGNC:28757]",{"v":1.67689649441786,"d":"1.68"},{"v":0.864908217304625,"d":"0.86"},{"v":1.9388143861596,"d":"1.94"},{"v":0.955174692570587,"d":"0.96"},{"v":0.152563221107548,"d":"0.15"},{"v":0.940427826220425,"d":"0.94"},"up","no"]
["MSTRG.4092","LIG4","ENST00000614526;ENST00000356922;ENST00000611712;ENST00000405925;ENST00000442234","GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0003677(DNA binding);GO:0051301(cell division);GO:0005886(plasma membrane);GO:0005925(focal adhesion);GO:0006281(DNA repair);GO:0016874(ligase activity);GO:0005515(protein binding);GO:0006310(DNA recombination);GO:0006974(cellular response to DNA damage stimulus);GO:0007049(cell cycle);GO:0006260(DNA replication);GO:0003909(DNA ligase activity);GO:0003910(DNA ligase (ATP) activity);GO:0051103(DNA ligation involved in DNA repair);GO:0071897(DNA biosynthetic process);GO:0005737(cytoplasm);GO:0008283(cell proliferation);GO:0000784(nuclear chromosome, telomeric region);GO:0008022(protein C-terminus binding);GO:0043524(negative regulation of neuron apoptotic process);GO:0010332(response to gamma radiation);GO:0006303(double-strand break repair via nonhomologous end joining);GO:0051402(neuron apoptotic process);GO:0001701(in utero embryonic development);GO:0048146(positive regulation of fibroblast proliferation);GO:0050769(positive regulation of neurogenesis);GO:0000793(condensed chromosome);GO:0006302(double-strand break repair);GO:0075713(establishment of integrated proviral latency);GO:0045190(isotype switching);GO:0007417(central nervous system development);GO:0051276(chromosome organization);GO:0033151(V(D)J recombination);GO:0000012(single strand break repair);GO:0006266(DNA ligation);GO:0097680(double-strand break repair via classical nonhomologous end joining);GO:0070419(nonhomologous end joining complex);GO:0033077(T cell differentiation in thymus);GO:0006297(nucleotide-excision repair, DNA gap filling);GO:0002328(pro-B cell differentiation);GO:0035019(somatic stem cell population maintenance);GO:0010165(response to X-ray);GO:0033152(immunoglobulin V(D)J recombination);GO:0033153(T cell receptor V(D)J recombination);GO:0051102(DNA ligation involved in DNA recombination);GO:2001252(positive regulation of chromosome organization);GO:0005958(DNA-dependent protein kinase-DNA ligase 4 complex);GO:0032807(DNA ligase IV complex);GO:0010212(response to ionizing radiation);GO:0071285(cellular response to lithium ion);GO:0071285(cellular response to lithium ion)","03450(Non-homologous end-joining);03450(Non-homologous end-joining)","K10777","EC:6.5.1.1","DNA ligase 4 [Source:HGNC Symbol;Acc:HGNC:6601]",{"v":1.18422991474812,"d":"1.18"},{"v":2.34295932527923,"d":"2.34"},{"v":0.505441943430659,"d":"0.51"},{"v":-0.984382705498612,"d":"-0.98"},{"v":0.152674975392301,"d":"0.15"},{"v":0.940427826220425,"d":"0.94"},"down","no"]
["MSTRG.7232","EVPL","ENST00000301607;ENST00000593037;ENST00000589231;ENST00000586740;ENST00000587569","GO:0005198(structural molecule activity);GO:0005856(cytoskeleton);GO:0008544(epidermis development);GO:0019215(intermediate filament binding);GO:0001533(cornified envelope);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0045111(intermediate filament cytoskeleton);GO:0030054(cell junction);GO:0031424(keratinization);GO:0045296(cadherin binding);GO:0070062(extracellular exosome);GO:0030674(protein binding, bridging);GO:0030216(keratinocyte differentiation);GO:0070268(cornification);GO:0030057(desmosome);GO:0018149(peptide cross-linking);GO:0018149(peptide cross-linking)","NA","NA","NA","envoplakin [Source:HGNC Symbol;Acc:HGNC:3503]",{"v":0.320564752463382,"d":"0.32"},{"v":0.164229759254328,"d":"0.16"},{"v":1.95192852939005,"d":"1.95"},{"v":0.964900229036949,"d":"0.96"},{"v":0.152702749827198,"d":"0.15"},{"v":0.940427826220425,"d":"0.94"},"up","no"]
["ENSG00000164867","NOS3","ENST00000297494;ENST00000473057;ENST00000484524;ENST00000468293;ENST00000475454","GO:0045766(positive regulation of angiogenesis);GO:0008285(negative regulation of cell proliferation);GO:0005737(cytoplasm);GO:0005634(nucleus);GO:0016020(membrane);GO:0046872(metal ion binding);GO:0016491(oxidoreductase activity);GO:0050660(flavin adenine dinucleotide binding);GO:0050661(NADP binding);GO:0055114(oxidation-reduction process);GO:0005794(Golgi apparatus);GO:0005886(plasma membrane);GO:0005506(iron ion binding);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0005901(caveola);GO:0020037(heme binding);GO:0005516(calmodulin binding);GO:0010181(FMN binding);GO:0004517(nitric-oxide synthase activity);GO:0006809(nitric oxide biosynthetic process);GO:0005829(cytosol);GO:0000139(Golgi membrane);GO:0050999(regulation of nitric-oxide synthase activity);GO:0030666(endocytic vesicle membrane);GO:0007005(mitochondrion organization);GO:0043542(endothelial cell migration);GO:1902042(negative regulation of extrinsic apoptotic signaling pathway via death domain receptors);GO:0003785(actin monomer binding);GO:0008217(regulation of blood pressure);GO:0006527(arginine catabolic process);GO:0010544(negative regulation of platelet activation);GO:0001974(blood vessel remodeling);GO:0019430(removal of superoxide radicals);GO:0045454(cell redox homeostasis);GO:0003100(regulation of systemic arterial blood pressure by endothelin);GO:0014806(smooth muscle hyperplasia);GO:0003958(NADPH-hemoprotein reductase activity);GO:0034617(tetrahydrobiopterin binding);GO:0034618(arginine binding);GO:0046870(cadmium ion binding);GO:0097110(scaffold protein binding);GO:0001525(angiogenesis);GO:0001542(ovulation from ovarian follicle);GO:0001701(in utero embryonic development);GO:0002028(regulation of sodium ion transport);GO:0003057(regulation of the force of heart contraction by chemical signal);GO:0007263(nitric oxide mediated signal transduction);GO:0009408(response to heat);GO:0014740(negative regulation of muscle hyperplasia);GO:0030324(lung development);GO:0031284(positive regulation of guanylate cyclase activity);GO:0031663(lipopolysaccharide-mediated signaling pathway);GO:0034405(response to fluid shear stress);GO:0042311(vasodilation);GO:0043267(negative regulation of potassium ion transport);GO:0045776(negative regulation of blood pressure);GO:0050880(regulation of blood vessel size);GO:0051346(negative regulation of hydrolase activity);GO:0051926(negative regulation of calcium ion transport);GO:0097755(positive regulation of blood vessel diameter);GO:0097755(positive regulation of blood vessel diameter)","00220(Arginine biosynthesis);00330(Arginine and proline metabolism);04370(VEGF signaling pathway);04371(Apelin signaling pathway);04066(HIF-1 signaling pathway);04020(Calcium signaling pathway);04071(Sphingolipid signaling pathway);04022(cGMP - PKG signaling pathway);04151(PI3K-Akt signaling pathway);04611(Platelet activation);04915(Estrogen signaling pathway);04921(Oxytocin signaling pathway);04926(Relaxin signaling pathway);05418(Fluid shear stress and atherosclerosis);04931(Insulin resistance);04933(AGE-RAGE signaling pathway in diabetic complications);04933(AGE-RAGE signaling pathway in diabetic complications)","K13242","EC:1.14.13.39","nitric oxide synthase 3 [Source:HGNC Symbol;Acc:HGNC:7876]",{"v":0.352879956324542,"d":"0.35"},{"v":0.177671188476398,"d":"0.18"},{"v":1.98614057434202,"d":"1.99"},{"v":0.989967737029869,"d":"0.99"},{"v":0.152730996645133,"d":"0.15"},{"v":0.940427826220425,"d":"0.94"},"up","no"]
["MSTRG.9030","RGPD4","MSTRG.9030.1","NA","NA","NA","NA",null,{"v":7.143669,"d":"7.14"},{"v":3.599615,"d":"3.60"},{"v":1.98456473817339,"d":"1.98"},{"v":0.9888226250328,"d":"0.99"},{"v":0.152755092848958,"d":"0.15"},{"v":0.940427826220425,"d":"0.94"},"up","no"]
["MSTRG.9923","FP671120.1","ENST00000623664","NA","NA","NA","NA",null,{"v":1.659717,"d":"1.66"},{"v":0.867305,"d":"0.87"},{"v":1.91364860112648,"d":"1.91"},{"v":0.936325935385364,"d":"0.94"},{"v":0.152974011860207,"d":"0.15"},{"v":0.940620598459077,"d":"0.94"},"up","no"]
["MSTRG.4388","TMX1","ENST00000457354;ENST00000556683;ENST00000555574","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0055114(oxidation-reduction process);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0045454(cell redox homeostasis);GO:0034976(response to endoplasmic reticulum stress);GO:0006457(protein folding);GO:0015036(disulfide oxidoreductase activity);GO:0003756(protein disulfide isomerase activity);GO:0005623(cell);GO:0005623(cell)","NA","NA","NA","thioredoxin related transmembrane protein 1 [Source:HGNC Symbol;Acc:HGNC:15487]",{"v":1.74538534741054,"d":"1.75"},{"v":3.43835959013114,"d":"3.44"},{"v":0.507621527550576,"d":"0.51"},{"v":-0.978174841642365,"d":"-0.98"},{"v":0.152980171361832,"d":"0.15"},{"v":0.940620598459077,"d":"0.94"},"down","no"]
["ENSG00000110583","NAA40","ENST00000377793;ENST00000536939;ENST00000534965;ENST00000544194;ENST00000545161;ENST00000539656;ENST00000338447","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016740(transferase activity);GO:0016746(transferase activity, transferring acyl groups);GO:0008080(N-acetyltransferase activity);GO:0006629(lipid metabolic process);GO:0043967(histone H4 acetylation);GO:0010485(H4 histone acetyltransferase activity);GO:0043968(histone H2A acetylation);GO:0006474(N-terminal protein amino acid acetylation);GO:0043998(H2A histone acetyltransferase activity);GO:1990189(peptide-serine-N-acetyltransferase activity);GO:1990189(peptide-serine-N-acetyltransferase activity)","NA","NA","NA","N(alpha)-acetyltransferase 40, NatD catalytic subunit [Source:HGNC Symbol;Acc:HGNC:25845]",{"v":1.80698501334336,"d":"1.81"},{"v":0.949104174215373,"d":"0.95"},{"v":1.90388480256891,"d":"1.90"},{"v":0.928946188839977,"d":"0.93"},{"v":0.153046370182812,"d":"0.15"},{"v":0.940620598459077,"d":"0.94"},"up","no"]
["MSTRG.12087","TRIM23","ENST00000231524;ENST00000513794","GO:0003676(nucleic acid binding);GO:0016020(membrane);GO:0005525(GTP binding);GO:0007264(small GTPase mediated signal transduction);GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0016740(transferase activity);GO:0016567(protein ubiquitination);GO:0005794(Golgi apparatus);GO:0005622(intracellular);GO:0005765(lysosomal membrane);GO:0043085(positive regulation of catalytic activity);GO:0005515(protein binding);GO:0000139(Golgi membrane);GO:0005764(lysosome);GO:0042802(identical protein binding);GO:0070062(extracellular exosome);GO:0012505(endomembrane system);GO:0016032(viral process);GO:0003924(GTPase activity);GO:0008047(enzyme activator activity);GO:0004842(ubiquitin-protein transferase activity);GO:0019003(GDP binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005737(cytoplasm)","NA","NA","NA","tripartite motif containing 23 [Source:HGNC Symbol;Acc:HGNC:660]",{"v":1.53223200083212,"d":"1.53"},{"v":3.012007527772,"d":"3.01"},{"v":0.508707892229446,"d":"0.51"},{"v":-0.975090618158886,"d":"-0.98"},{"v":0.153149830547791,"d":"0.15"},{"v":0.940620598459077,"d":"0.94"},"down","no"]
["ENSG00000205664","BX890604.1","ENST00000486571;ENST00000471090;ENST00000483854;ENST00000469903;ENST00000461011;ENST00000475317;ENST00000490920;ENST00000425492","NA","NA","NA","NA",null,{"v":0.76563617616241,"d":"0.77"},{"v":0.389638947609692,"d":"0.39"},{"v":1.96498882070013,"d":"1.96"},{"v":0.974521104663853,"d":"0.97"},{"v":0.153176963426196,"d":"0.15"},{"v":0.940620598459077,"d":"0.94"},"up","no"]
["MSTRG.10989","TKT","ENST00000472528;ENST00000460343;ENST00000462138;ENST00000450814;ENST00000423516;ENST00000466765;ENST00000494523;ENST00000483706;ENST00000469678;ENST00000296289;ENST00000487660;ENST00000460243;ENST00000423525;ENST00000461139","GO:0016607(nuclear speck);GO:0046872(metal ion binding);GO:0005654(nucleoplasm);GO:0016740(transferase activity);GO:0003824(catalytic activity);GO:0008152(metabolic process);GO:0042803(protein homodimerization activity);GO:0005515(protein binding);GO:0048037(cofactor binding);GO:0016604(nuclear body);GO:0005777(peroxisome);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0031982(vesicle);GO:0006098(pentose-phosphate shunt);GO:0004802(transketolase activity);GO:0005999(xylulose biosynthetic process);GO:0009052(pentose-phosphate shunt, non-oxidative branch);GO:0046166(glyceraldehyde-3-phosphate biosynthetic process);GO:0040008(regulation of growth);GO:0043209(myelin sheath);GO:0043209(myelin sheath)","00030(Pentose phosphate pathway);01051(Biosynthesis of ansamycins);01051(Biosynthesis of ansamycins)","K00615","EC:2.2.1.1","transketolase [Source:HGNC Symbol;Acc:HGNC:11834]",{"v":33.8645382111076,"d":"33.86"},{"v":66.212884022089,"d":"66.21"},{"v":0.511449375922218,"d":"0.51"},{"v":-0.967336648114046,"d":"-0.97"},{"v":0.153447472638955,"d":"0.15"},{"v":0.940914080743292,"d":"0.94"},"down","no"]
["ENSG00000149115","TNKS1BP1","ENST00000532437;ENST00000532273;ENST00000358252;ENST00000530920;ENST00000427750","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005694(chromosome);GO:0005856(cytoskeleton);GO:0006977(DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest);GO:0005829(cytosol);GO:0045296(cadherin binding);GO:0005515(protein binding);GO:0000289(nuclear-transcribed mRNA poly(A) tail shortening);GO:0030014(CCR4-NOT complex);GO:0005913(cell-cell adherens junction);GO:0033138(positive regulation of peptidyl-serine phosphorylation);GO:0019899(enzyme binding);GO:0010800(positive regulation of peptidyl-threonine phosphorylation);GO:0031954(positive regulation of protein autophosphorylation);GO:0071479(cellular response to ionizing radiation);GO:0005720(nuclear heterochromatin);GO:0044877(macromolecular complex binding);GO:0006302(double-strand break repair);GO:0071532(ankyrin repeat binding);GO:0007004(telomere maintenance via telomerase);GO:0007004(telomere maintenance via telomerase)","NA","NA","NA","tankyrase 1 binding protein 1 [Source:HGNC Symbol;Acc:HGNC:19081]",{"v":0.756135234018744,"d":"0.76"},{"v":0.395903746398098,"d":"0.40"},{"v":1.90989663749839,"d":"1.91"},{"v":0.93349456255235,"d":"0.93"},{"v":0.153752337027787,"d":"0.15"},{"v":0.940914080743292,"d":"0.94"},"up","no"]
["MSTRG.6796","RARA","ENST00000394081;ENST00000577646;ENST00000394089;ENST00000254066;ENST00000425707;ENST00000420042;ENST00000579727;ENST00000582914","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0005829(cytosol);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0031490(chromatin DNA binding);GO:0043565(sequence-specific DNA binding);GO:0015629(actin cytoskeleton);GO:0005515(protein binding);GO:0003707(steroid hormone receptor activity);GO:0043401(steroid hormone mediated signaling pathway);GO:0003713(transcription coactivator activity);GO:0045893(positive regulation of transcription, DNA-templated);GO:0003714(transcription corepressor activity);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0005654(nucleoplasm);GO:0003708(retinoic acid receptor activity);GO:0048384(retinoic acid receptor signaling pathway);GO:0005102(receptor binding);GO:0008284(positive regulation of cell proliferation);GO:0009986(cell surface);GO:0019899(enzyme binding);GO:0019904(protein domain specific binding);GO:0032689(negative regulation of interferon-gamma production);GO:0032720(negative regulation of tumor necrosis factor production);GO:0008134(transcription factor binding);GO:0045892(negative regulation of transcription, DNA-templated);GO:0000790(nuclear chromatin);GO:0046982(protein heterodimerization activity);GO:0006367(transcription initiation from RNA polymerase II promoter);GO:0006468(protein phosphorylation);GO:0071300(cellular response to retinoic acid);GO:0043277(apoptotic cell clearance);GO:0032526(response to retinoic acid);GO:0045787(positive regulation of cell cycle);GO:0071391(cellular response to estrogen stimulus);GO:0001972(retinoic acid binding);GO:0051018(protein kinase A binding);GO:0007165(signal transduction);GO:0043422(protein kinase B binding);GO:0000900(translation repressor activity, nucleic acid binding);GO:0000975(regulatory region DNA binding);GO:0000977(RNA polymerase II regulatory region sequence-specific DNA binding);GO:0001012(RNA polymerase II regulatory region DNA binding);GO:0004879(RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding);GO:0008144(drug binding);GO:0042826(histone deacetylase binding);GO:0044212(transcription regulatory region DNA binding);GO:0044323(retinoic acid-responsive element binding);GO:0048027(mRNA 5'-UTR binding);GO:0051393(alpha-actinin binding);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0001657(ureteric bud development);GO:0001843(neural tube closure);GO:0001889(liver development);GO:0002068(glandular epithelial cell development);GO:0003148(outflow tract septum morphogenesis);GO:0003417(growth plate cartilage development);GO:0007281(germ cell development);GO:0007283(spermatogenesis);GO:0007565(female pregnancy);GO:0008285(negative regulation of cell proliferation);GO:0008584(male gonad development);GO:0010628(positive regulation of gene expression);GO:0010629(negative regulation of gene expression);GO:0017148(negative regulation of translation);GO:0021766(hippocampus development);GO:0030850(prostate gland development);GO:0030852(regulation of granulocyte differentiation);GO:0030853(negative regulation of granulocyte differentiation);GO:0031076(embryonic camera-type eye development);GO:0031641(regulation of myelination);GO:0032355(response to estradiol);GO:0032736(positive regulation of interleukin-13 production);GO:0032753(positive regulation of interleukin-4 production);GO:0032754(positive regulation of interleukin-5 production);GO:0033189(response to vitamin A);GO:0034097(response to cytokine);GO:0035264(multicellular organism growth);GO:0042981(regulation of apoptotic process);GO:0043066(negative regulation of apoptotic process);GO:0045471(response to ethanol);GO:0045596(negative regulation of cell differentiation);GO:0045630(positive regulation of T-helper 2 cell differentiation);GO:0045666(positive regulation of neuron differentiation);GO:0045947(negative regulation of translational initiation);GO:0048167(regulation of synaptic plasticity);GO:0051099(positive regulation of binding);GO:0055012(ventricular cardiac muscle cell differentiation);GO:0060010(Sertoli cell fate commitment);GO:0060173(limb development);GO:0060324(face development);GO:0060348(bone development);GO:0060534(trachea cartilage development);GO:0060591(chondroblast differentiation);GO:0061037(negative regulation of cartilage development);GO:0071222(cellular response to lipopolysaccharide);GO:0030425(dendrite);GO:0043005(neuron projection);GO:0043025(neuronal cell body);GO:0048471(perinuclear region of cytoplasm);GO:0048471(perinuclear region of cytoplasm)","04659(Th17 cell differentiation);05200(Pathways in cancer);05202(Transcriptional misregulation in cancers);05221(Acute myeloid leukemia);05221(Acute myeloid leukemia)","K08527","NA","retinoic acid receptor alpha [Source:HGNC Symbol;Acc:HGNC:9864]",{"v":11.3763402502642,"d":"11.38"},{"v":22.2627828099768,"d":"22.26"},{"v":0.511002615772096,"d":"0.51"},{"v":-0.968597418691643,"d":"-0.97"},{"v":0.153775862620788,"d":"0.15"},{"v":0.940914080743292,"d":"0.94"},"down","no"]
["ENSG00000145725","PPIP5K2","ENST00000321521;ENST00000509597;ENST00000627916;ENST00000502481;ENST00000511022;ENST00000515845;ENST00000510672;ENST00000507310;ENST00000358359;ENST00000511724;ENST00000414217;ENST00000504083;ENST00000508935;ENST00000504275","GO:0005737(cytoplasm);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0005829(cytosol);GO:0016311(dephosphorylation);GO:0003993(acid phosphatase activity);GO:0006020(inositol metabolic process);GO:0043647(inositol phosphate metabolic process);GO:0000827(inositol-1,3,4,5,6-pentakisphosphate kinase activity);GO:0000828(inositol hexakisphosphate kinase activity);GO:0000829(inositol heptakisphosphate kinase activity);GO:0000832(inositol hexakisphosphate 5-kinase activity);GO:0033857(diphosphoinositol-pentakisphosphate kinase activity);GO:0052723(inositol hexakisphosphate 1-kinase activity);GO:0052724(inositol hexakisphosphate 3-kinase activity);GO:0032958(inositol phosphate biosynthetic process);GO:0032958(inositol phosphate biosynthetic process)","04070(Phosphatidylinositol signaling system);04070(Phosphatidylinositol signaling system)","K13024","EC:2.7.4.24","diphosphoinositol pentakisphosphate kinase 2 [Source:HGNC Symbol;Acc:HGNC:29035]",{"v":1.19165968986682,"d":"1.19"},{"v":2.33101952929936,"d":"2.33"},{"v":0.511218235149235,"d":"0.51"},{"v":-0.96798879676723,"d":"-0.97"},{"v":0.153787761608652,"d":"0.15"},{"v":0.940914080743292,"d":"0.94"},"down","no"]
["MSTRG.4494","ZFP36L1","ENST00000439696;ENST00000555997;ENST00000557022;ENST00000336440;ENST00000557086;ENST00000553375","GO:0003723(RNA binding);GO:0006397(mRNA processing);GO:0006810(transport);GO:0051028(mRNA transport);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0003677(DNA binding);GO:0030529(intracellular ribonucleoprotein complex);GO:0005515(protein binding);GO:0007275(multicellular organism development);GO:0006355(regulation of transcription, DNA-templated);GO:0003729(mRNA binding);GO:0017091(AU-rich element binding);GO:0035925(mRNA 3'-UTR AU-rich region binding);GO:0000165(MAPK cascade);GO:0000288(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay);GO:0001570(vasculogenesis);GO:0003342(proepicardium development);GO:0006402(mRNA catabolic process);GO:0006417(regulation of translation);GO:0006915(apoptotic process);GO:0007507(heart development);GO:0008283(cell proliferation);GO:0021915(neural tube development);GO:0031086(nuclear-transcribed mRNA catabolic process, deadenylation-independent decay);GO:0033077(T cell differentiation in thymus);GO:0035264(multicellular organism growth);GO:0038066(p38MAPK cascade);GO:0043488(regulation of mRNA stability);GO:0043491(protein kinase B signaling);GO:0044344(cellular response to fibroblast growth factor stimulus);GO:0045577(regulation of B cell differentiation);GO:0045600(positive regulation of fat cell differentiation);GO:0045661(regulation of myoblast differentiation);GO:0048382(mesendoderm development);GO:0048568(embryonic organ development);GO:0060710(chorio-allantoic fusion);GO:0060712(spongiotrophoblast layer development);GO:0061158(3'-UTR-mediated mRNA destabilization);GO:0071320(cellular response to cAMP);GO:0071375(cellular response to peptide hormone stimulus);GO:0071472(cellular response to salt stress);GO:0072091(regulation of stem cell proliferation);GO:0097403(cellular response to raffinose);GO:1900153(positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay);GO:1901991(negative regulation of mitotic cell cycle phase transition);GO:0005829(cytosol);GO:0000932(P-body);GO:0071356(cellular response to tumor necrosis factor);GO:0070371(ERK1 and ERK2 cascade);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0014065(phosphatidylinositol 3-kinase signaling);GO:0071560(cellular response to transforming growth factor beta stimulus);GO:0032869(cellular response to insulin stimulus);GO:0071889(14-3-3 protein binding);GO:0071456(cellular response to hypoxia);GO:0031440(regulation of mRNA 3'-end processing);GO:0009611(response to wounding);GO:0071364(cellular response to epidermal growth factor stimulus);GO:0045616(regulation of keratinocyte differentiation);GO:0010468(regulation of gene expression);GO:0045647(negative regulation of erythrocyte differentiation);GO:0071385(cellular response to glucocorticoid stimulus);GO:1904628(cellular response to phorbol 13-acetate 12-myristate);GO:0010837(regulation of keratinocyte proliferation);GO:0045657(positive regulation of monocyte differentiation);GO:1902172(regulation of keratinocyte apoptotic process);GO:1904582(positive regulation of intracellular mRNA localization);GO:1904582(positive regulation of intracellular mRNA localization)","04218(Cellular senescence);04218(Cellular senescence)","K18753","NA","ZFP36 ring finger protein like 1 [Source:HGNC Symbol;Acc:HGNC:1107]",{"v":11.3265526437984,"d":"11.33"},{"v":22.143587951938,"d":"22.14"},{"v":0.511504850450719,"d":"0.51"},{"v":-0.967180174197266,"d":"-0.97"},{"v":0.153875185478761,"d":"0.15"},{"v":0.940914080743292,"d":"0.94"},"down","no"]
["MSTRG.1845","KLLN","ENST00000445946","GO:0005634(nucleus);GO:0005730(nucleolus);GO:0003677(DNA binding);GO:0007049(cell cycle);GO:0006915(apoptotic process);GO:0007050(cell cycle arrest)","NA","NA","NA","killin, p53-regulated DNA replication inhibitor [Source:HGNC Symbol;Acc:HGNC:37212]",{"v":0.166252,"d":"0.17"},{"v":0.344623,"d":"0.34"},{"v":0.482417018016789,"d":"0.48"},{"v":-1.05164729342181,"d":"-1.05"},{"v":0.153900052785222,"d":"0.15"},{"v":0.940914080743292,"d":"0.94"},"down","no"]
["MSTRG.9573","CDC25B","ENST00000245960;ENST00000467519;ENST00000439880;ENST00000468979;ENST00000495915;ENST00000480816;ENST00000344256","GO:0005737(cytoplasm);GO:0016787(hydrolase activity);GO:0005622(intracellular);GO:0051301(cell division);GO:0004725(protein tyrosine phosphatase activity);GO:0006470(protein dephosphorylation);GO:0035335(peptidyl-tyrosine dephosphorylation);GO:0004721(phosphoprotein phosphatase activity);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0007049(cell cycle);GO:1902751(positive regulation of cell cycle G2/M phase transition);GO:0000922(spindle pole);GO:0005813(centrosome);GO:0005815(microtubule organizing center);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0019901(protein kinase binding);GO:0000086(G2/M transition of mitotic cell cycle);GO:0006468(protein phosphorylation);GO:0000278(mitotic cell cycle);GO:0032467(positive regulation of cytokinesis);GO:0008284(positive regulation of cell proliferation);GO:0045931(positive regulation of mitotic cell cycle);GO:0001556(oocyte maturation);GO:0007144(female meiosis I);GO:0045860(positive regulation of protein kinase activity);GO:0005634(nucleus);GO:0005634(nucleus)","04010(MAPK signaling pathway);04110(Cell cycle);04914(Progesterone-mediated oocyte maturation);05206(MicroRNAs in cancer);05206(MicroRNAs in cancer)","K05866","EC:3.1.3.48","cell division cycle 25B [Source:HGNC Symbol;Acc:HGNC:1726]",{"v":22.0324275363931,"d":"22.03"},{"v":11.693538147427,"d":"11.69"},{"v":1.88415407369591,"d":"1.88"},{"v":0.913916943861747,"d":"0.91"},{"v":0.153967239961717,"d":"0.15"},{"v":0.940914080743292,"d":"0.94"},"up","no"]
["MSTRG.5033","TRIM69","ENST00000560141;ENST00000560442;ENST00000558173;ENST00000559390;ENST00000329464","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016607(nuclear speck);GO:0046872(metal ion binding);GO:0016740(transferase activity);GO:0016567(protein ubiquitination);GO:0005515(protein binding);GO:0006915(apoptotic process);GO:0005829(cytosol);GO:0000209(protein polyubiquitination);GO:0004842(ubiquitin-protein transferase activity);GO:0004842(ubiquitin-protein transferase activity)","NA","NA","NA","tripartite motif containing 69 [Source:HGNC Symbol;Acc:HGNC:17857]",{"v":0.516217166432812,"d":"0.52"},{"v":1.02053996546141,"d":"1.02"},{"v":0.505827487313952,"d":"0.51"},{"v":-0.983282657858469,"d":"-0.98"},{"v":0.153993220990002,"d":"0.15"},{"v":0.940914080743292,"d":"0.94"},"down","no"]
["MSTRG.1698","AGAP4","ENST00000616763;ENST00000448048;ENST00000495243;ENST00000490752;ENST00000492347;ENST00000618171;ENST00000430779","GO:0046872(metal ion binding);GO:0043547(positive regulation of GTPase activity);GO:0005096(GTPase activator activity);GO:0005096(GTPase activator activity)","NA","NA","NA","ArfGAP with GTPase domain, ankyrin repeat and PH domain 4 [Source:HGNC Symbol;Acc:HGNC:23459]",{"v":0.828577755325274,"d":"0.83"},{"v":1.65043964680484,"d":"1.65"},{"v":0.502034568140286,"d":"0.50"},{"v":-0.994141388943281,"d":"-0.99"},{"v":0.153993805345587,"d":"0.15"},{"v":0.940914080743292,"d":"0.94"},"down","no"]
["MSTRG.7254","SNHG16","ENST00000590435;ENST00000448136;ENST00000493536;ENST00000586846;ENST00000587743;ENST00000586942;ENST00000591956","NA","NA","NA","NA","small nucleolar RNA host gene 16 [Source:HGNC Symbol;Acc:HGNC:44352]",{"v":2.18247655165983,"d":"2.18"},{"v":4.2843408461395,"d":"4.28"},{"v":0.509407778241173,"d":"0.51"},{"v":-0.973107106330822,"d":"-0.97"},{"v":0.154170568806758,"d":"0.15"},{"v":0.940914080743292,"d":"0.94"},"down","no"]
["ENSG00000117090","SLAMF1","ENST00000302035;ENST00000494463;ENST00000538290;ENST00000235739","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0007155(cell adhesion);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0009986(cell surface);GO:0004872(receptor activity);GO:0002376(immune system process);GO:0045087(innate immune response);GO:0007165(signal transduction);GO:0002250(adaptive immune response);GO:0046718(viral entry into host cell);GO:0070062(extracellular exosome);GO:0016032(viral process);GO:0032720(negative regulation of tumor necrosis factor production);GO:0070374(positive regulation of ERK1 and ERK2 cascade);GO:0006909(phagocytosis);GO:0004888(transmembrane signaling receptor activity);GO:0001618(virus receptor activity);GO:0046330(positive regulation of JNK cascade);GO:0008284(positive regulation of cell proliferation);GO:0003823(antigen binding);GO:0032715(negative regulation of interleukin-6 production);GO:0032695(negative regulation of interleukin-12 production);GO:0002277(myeloid dendritic cell activation involved in immune response);GO:0046649(lymphocyte activation);GO:2000349(negative regulation of CD40 signaling pathway);GO:0042802(identical protein binding);GO:0001779(natural killer cell differentiation);GO:0001787(natural killer cell proliferation);GO:0002232(leukocyte chemotaxis involved in inflammatory response);GO:0002725(negative regulation of T cell cytokine production);GO:0010759(positive regulation of macrophage chemotaxis);GO:0031338(regulation of vesicle fusion);GO:0035744(T-helper 1 cell cytokine production);GO:0042104(positive regulation of activated T cell proliferation);GO:0050790(regulation of catalytic activity);GO:1902714(negative regulation of interferon-gamma secretion);GO:1902715(positive regulation of interferon-gamma secretion);GO:2000510(positive regulation of dendritic cell chemotaxis);GO:0009897(external side of plasma membrane);GO:0045335(phagocytic vesicle);GO:0045335(phagocytic vesicle)","05162(Measles);05162(Measles)","K06536","NA","signaling lymphocytic activation molecule family member 1 [Source:HGNC Symbol;Acc:HGNC:10903]",{"v":3.26075173249004,"d":"3.26"},{"v":1.72219642726634,"d":"1.72"},{"v":1.89336807396928,"d":"1.89"},{"v":0.920954900672555,"d":"0.92"},{"v":0.154190280120373,"d":"0.15"},{"v":0.940914080743292,"d":"0.94"},"up","no"]
["ENSG00000159882","ZNF230","ENST00000429154;ENST00000585568;ENST00000585491;ENST00000589275;ENST00000585632","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0005622(intracellular);GO:0005515(protein binding);GO:0005515(protein binding)","NA","NA","NA","zinc finger protein 230 [Source:HGNC Symbol;Acc:HGNC:13024]",{"v":0.823526712289616,"d":"0.82"},{"v":1.62331615814544,"d":"1.62"},{"v":0.507311350384423,"d":"0.51"},{"v":-0.979056655766365,"d":"-0.98"},{"v":0.154202574485739,"d":"0.15"},{"v":0.940914080743292,"d":"0.94"},"down","no"]
["MSTRG.13648","NIPSNAP2;ZNF713;MRPS17;AC092647.5","ENST00000322090;ENST00000470036;ENST00000446692;ENST00000466630;ENST00000464772;ENST00000411863;ENST00000633730;ENST00000285298;ENST00000446778;ENST00000443449;ENST00000472404;ENST00000415967;ENST00000429591;ENST00000487370;ENST00000426595;ENST00000482436;ENST00000497279","GO:0005737(cytoplasm);GO:0005739(mitochondrion);GO:0005515(protein binding);GO:0005887(integral component of plasma membrane);GO:0016020(membrane);GO:0006119(oxidative phosphorylation);GO:0006754(ATP biosynthetic process);GO:1901843(positive regulation of high voltage-gated calcium channel activity);GO:2000984(negative regulation of ATP citrate synthase activity);GO:0003676(nucleic acid binding);GO:0046872(metal ion binding);GO:0006355(regulation of transcription, DNA-templated);GO:0005622(intracellular);GO:0005634(nucleus);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0003723(RNA binding);GO:0006412(translation);GO:0030529(intracellular ribonucleoprotein complex);GO:0003735(structural constituent of ribosome);GO:0005840(ribosome);GO:0032543(mitochondrial translation);GO:0019843(rRNA binding);GO:0005743(mitochondrial inner membrane);GO:0070125(mitochondrial translational elongation);GO:0070126(mitochondrial translational termination);GO:0005763(mitochondrial small ribosomal subunit);GO:2000984(negative regulation of ATP citrate synthase activity)","03010(Ribosome);03010(Ribosome)","K02961","NA","nipsnap homolog 2 [Source:HGNC Symbol;Acc:HGNC:4179];zinc finger protein 713 [Source:HGNC Symbol;Acc:HGNC:22043];mitochondrial ribosomal protein S17 [Source:HGNC Symbol;Acc:HGNC:14047]",{"v":0.780512151508682,"d":"0.78"},{"v":1.53687075825505,"d":"1.54"},{"v":0.507858027304045,"d":"0.51"},{"v":-0.977502849722803,"d":"-0.98"},{"v":0.154240524446708,"d":"0.15"},{"v":0.940914080743292,"d":"0.94"},"down","no"]
["ENSG00000006757","PNPLA4","ENST00000381042;ENST00000444736;ENST00000442940","GO:0016787(hydrolase activity);GO:0006629(lipid metabolic process);GO:0008152(metabolic process);GO:0016042(lipid catabolic process);GO:0005739(mitochondrion);GO:0042572(retinol metabolic process);GO:0004806(triglyceride lipase activity);GO:0050253(retinyl-palmitate esterase activity);GO:0016020(membrane);GO:0003674(molecular_function);GO:0008150(biological_process);GO:0005575(cellular_component);GO:0005829(cytosol);GO:0019433(triglyceride catabolic process);GO:0055088(lipid homeostasis);GO:0005811(lipid particle);GO:0005811(lipid particle)","00830(Retinol metabolism);00830(Retinol metabolism)","K11157","EC:3.1.1.-","patatin like phospholipase domain containing 4 [Source:HGNC Symbol;Acc:HGNC:24887]",{"v":0.805490292356873,"d":"0.81"},{"v":0.416344700959024,"d":"0.42"},{"v":1.9346716566861,"d":"1.93"},{"v":0.952088739772579,"d":"0.95"},{"v":0.15468449703644,"d":"0.15"},{"v":0.941801924237902,"d":"0.94"},"up","no"]
["MSTRG.11261","RNF13","ENST00000474348;ENST00000392894;ENST00000493238;ENST00000361785;ENST00000459632;ENST00000466478;ENST00000470151;ENST00000490631;ENST00000467977;ENST00000491086;ENST00000467996;ENST00000466795;ENST00000468648;ENST00000344229;ENST00000468289;ENST00000482083","GO:0005634(nucleus);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0043231(intracellular membrane-bounded organelle);GO:0046872(metal ion binding);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0016740(transferase activity);GO:0016567(protein ubiquitination);GO:0005794(Golgi apparatus);GO:0005765(lysosomal membrane);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005515(protein binding);GO:0000139(Golgi membrane);GO:0005764(lysosome);GO:0005768(endosome);GO:0031902(late endosome membrane);GO:0005637(nuclear inner membrane);GO:0004842(ubiquitin-protein transferase activity);GO:0051865(protein autoubiquitination);GO:0061630(ubiquitin protein ligase activity);GO:0061630(ubiquitin protein ligase activity)","NA","NA","NA","ring finger protein 13 [Source:HGNC Symbol;Acc:HGNC:10057]",{"v":11.0998677480055,"d":"11.10"},{"v":21.6897836822558,"d":"21.69"},{"v":0.511755576294022,"d":"0.51"},{"v":-0.966473177369204,"d":"-0.97"},{"v":0.154963952032524,"d":"0.15"},{"v":0.941801924237902,"d":"0.94"},"down","no"]
["MSTRG.14176","DEFA1B","ENST00000382689","GO:0005615(extracellular space);GO:0005576(extracellular region);GO:0006952(defense response);GO:0042742(defense response to bacterium);GO:0051607(defense response to virus);GO:0070062(extracellular exosome);GO:0031012(extracellular matrix);GO:0002227(innate immune response in mucosa);GO:0019731(antibacterial humoral response);GO:0050830(defense response to Gram-positive bacterium);GO:0061844(antimicrobial humoral immune response mediated by antimicrobial peptide);GO:0043312(neutrophil degranulation);GO:0006935(chemotaxis);GO:0006955(immune response);GO:0019730(antimicrobial humoral response);GO:0010818(T cell chemotaxis);GO:0005796(Golgi lumen);GO:0035578(azurophil granule lumen);GO:0030520(intracellular estrogen receptor signaling pathway);GO:0031640(killing of cells of other organism);GO:0042832(defense response to protozoan);GO:0050832(defense response to fungus);GO:0044657(pore formation in membrane of other organism during symbiotic interaction);GO:0051852(disruption by host of symbiont cells)","NA","NA","NA","defensin alpha 1B [Source:HGNC Symbol;Acc:HGNC:33596]",{"v":53.748623,"d":"53.75"},{"v":104.941162,"d":"104.94"},{"v":0.512178653024635,"d":"0.51"},{"v":-0.965280970451166,"d":"-0.97"},{"v":0.155094337996553,"d":"0.16"},{"v":0.941801924237902,"d":"0.94"},"down","no"]
["ENSG00000182389","CACNB4","ENST00000475848;ENST00000635743;ENST00000636810;ENST00000636831;ENST00000637942;ENST00000635731;ENST00000637762;ENST00000636507;ENST00000638083;ENST00000637828;ENST00000638005;ENST00000636129;ENST00000637884;ENST00000636834;ENST00000539935;ENST00000637622","GO:0006810(transport);GO:0005244(voltage-gated ion channel activity);GO:0006811(ion transport);GO:0034765(regulation of ion transmembrane transport);GO:0005515(protein binding);GO:0006816(calcium ion transport);GO:0070588(calcium ion transmembrane transport);GO:0005245(voltage-gated calcium channel activity);GO:0005262(calcium channel activity);GO:0005891(voltage-gated calcium channel complex);GO:0005886(plasma membrane);GO:0005829(cytosol);GO:0061337(cardiac conduction);GO:0008331(high voltage-gated calcium channel activity);GO:0007268(chemical synaptic transmission);GO:0007528(neuromuscular junction development);GO:0051899(membrane depolarization);GO:1901385(regulation of voltage-gated calcium channel activity);GO:0009898(cytoplasmic side of plasma membrane);GO:0009898(cytoplasmic side of plasma membrane)","04010(MAPK signaling pathway);04921(Oxytocin signaling pathway);04260(Cardiac muscle contraction);04261(Adrenergic signaling in cardiomyocytes);05410(Hypertrophic cardiomyopathy (HCM));05412(Arrhythmogenic right ventricular cardiomyopathy (ARVC));05414(Dilated cardiomyopathy (DCM));05414(Dilated cardiomyopathy (DCM))","K04865","NA","calcium voltage-gated channel auxiliary subunit beta 4 [Source:HGNC Symbol;Acc:HGNC:1404]",{"v":0.0338330088783501,"d":"0.03"},{"v":0.0676781725763759,"d":"0.07"},{"v":0.499910201330702,"d":"0.50"},{"v":-1.00025912745975,"d":"-1.00"},{"v":0.155204623923414,"d":"0.16"},{"v":0.941801924237902,"d":"0.94"},"down","no"]
["ENSG00000206190","ATP10A","ENST00000356865;ENST00000555450;ENST00000555815;ENST00000619904;ENST00000555756;ENST00000389967;ENST00000553577","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0000287(magnesium ion binding);GO:0016787(hydrolase activity);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005886(plasma membrane);GO:0006869(lipid transport);GO:0004012(phospholipid-translocating ATPase activity);GO:0015914(phospholipid transport);GO:0005515(protein binding);GO:0034220(ion transmembrane transport);GO:0008360(regulation of cell shape);GO:0045332(phospholipid translocation);GO:0045332(phospholipid translocation)","NA","NA","NA","ATPase phospholipid transporting 10A (putative) [Source:HGNC Symbol;Acc:HGNC:13542]",{"v":1.96945588024735,"d":"1.97"},{"v":1.04274926031633,"d":"1.04"},{"v":1.88871472289503,"d":"1.89"},{"v":0.917404809219517,"d":"0.92"},{"v":0.155220745076583,"d":"0.16"},{"v":0.941801924237902,"d":"0.94"},"up","no"]
["MSTRG.12278","LYRM7","ENST00000379380;ENST00000507584","GO:0005739(mitochondrion);GO:0005515(protein binding);GO:0005759(mitochondrial matrix);GO:0031966(mitochondrial membrane);GO:0045333(cellular respiration);GO:0034551(mitochondrial respiratory chain complex III assembly);GO:0034551(mitochondrial respiratory chain complex III assembly)","NA","NA","NA","LYR motif containing 7 [Source:HGNC Symbol;Acc:HGNC:28072]",{"v":0.847852,"d":"0.85"},{"v":0.446191,"d":"0.45"},{"v":1.90019969026717,"d":"1.90"},{"v":0.926151038040413,"d":"0.93"},{"v":0.15523389229625,"d":"0.16"},{"v":0.941801924237902,"d":"0.94"},"up","no"]
["ENSG00000103876","FAH","ENST00000561421;ENST00000537726;ENST00000558767;ENST00000558514;ENST00000539156;ENST00000407106;ENST00000261755;ENST00000559217;ENST00000559542;ENST00000558022;ENST00000558627","GO:0003824(catalytic activity);GO:0008152(metabolic process);GO:0009072(aromatic amino acid family metabolic process);GO:0004334(fumarylacetoacetase activity);GO:0046872(metal ion binding);GO:0016787(hydrolase activity);GO:0005515(protein binding);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0006559(L-phenylalanine catabolic process);GO:0006572(tyrosine catabolic process);GO:0006527(arginine catabolic process);GO:0006527(arginine catabolic process)","00350(Tyrosine metabolism);00350(Tyrosine metabolism)","K01555","EC:3.7.1.2","fumarylacetoacetate hydrolase [Source:HGNC Symbol;Acc:HGNC:3579]",{"v":0.683544125725612,"d":"0.68"},{"v":1.34760083661334,"d":"1.35"},{"v":0.507230410633633,"d":"0.51"},{"v":-0.979286851075832,"d":"-0.98"},{"v":0.155250119611346,"d":"0.16"},{"v":0.941801924237902,"d":"0.94"},"down","no"]
["MSTRG.14821","AGTPBP1","ENST00000357081;ENST00000337006;ENST00000489265;ENST00000491784;ENST00000376083;ENST00000376080;ENST00000628899","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0043231(intracellular membrane-bounded organelle);GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0005730(nucleolus);GO:0016787(hydrolase activity);GO:0005829(cytosol);GO:0005739(mitochondrion);GO:0008233(peptidase activity);GO:0006508(proteolysis);GO:0004181(metallocarboxypeptidase activity);GO:0021702(cerebellar Purkinje cell differentiation);GO:0004180(carboxypeptidase activity);GO:0008237(metallopeptidase activity);GO:0015631(tubulin binding);GO:0007005(mitochondrion organization);GO:0001754(eye photoreceptor cell differentiation);GO:0050905(neuromuscular process);GO:0021772(olfactory bulb development);GO:0035610(protein side chain deglutamylation);GO:0035609(C-terminal protein deglutamylation);GO:0007628(adult walking behavior);GO:0021549(cerebellum development);GO:0021680(cerebellar Purkinje cell layer development);GO:0042133(neurotransmitter metabolic process);GO:0060041(retina development in camera-type eye);GO:0060041(retina development in camera-type eye)","NA","NA","NA","ATP/GTP binding protein 1 [Source:HGNC Symbol;Acc:HGNC:17258]",{"v":6.92093314132415,"d":"6.92"},{"v":13.5083440299656,"d":"13.51"},{"v":0.512345045845103,"d":"0.51"},{"v":-0.964812354450766,"d":"-0.96"},{"v":0.155271185933282,"d":"0.16"},{"v":0.941801924237902,"d":"0.94"},"down","no"]
["MSTRG.4642","GLRX5","ENST00000331334;ENST00000557731;ENST00000553672","GO:0046872(metal ion binding);GO:0005739(mitochondrion);GO:0045454(cell redox homeostasis);GO:0055114(oxidation-reduction process);GO:0005759(mitochondrial matrix);GO:0051536(iron-sulfur cluster binding);GO:0009249(protein lipoylation);GO:0009055(electron carrier activity);GO:0015035(protein disulfide oxidoreductase activity);GO:0051537(2 iron, 2 sulfur cluster binding);GO:0030097(hemopoiesis);GO:0044281(small molecule metabolic process);GO:0015036(disulfide oxidoreductase activity);GO:0005634(nucleus);GO:0030425(dendrite);GO:0043025(neuronal cell body);GO:0043025(neuronal cell body)","NA","NA","NA","glutaredoxin 5 [Source:HGNC Symbol;Acc:HGNC:20134]",{"v":15.4461336801406,"d":"15.45"},{"v":8.20410040808436,"d":"8.20"},{"v":1.88273337865537,"d":"1.88"},{"v":0.912828708647553,"d":"0.91"},{"v":0.155293598931206,"d":"0.16"},{"v":0.941801924237902,"d":"0.94"},"up","no"]
["ENSG00000177034","MTX3","ENST00000512560;ENST00000509852;ENST00000617335","GO:0006810(transport);GO:0016020(membrane);GO:0015031(protein transport);GO:0005741(mitochondrial outer membrane);GO:0005739(mitochondrion);GO:0006626(protein targeting to mitochondrion);GO:0006626(protein targeting to mitochondrion)","NA","NA","NA","metaxin 3 [Source:HGNC Symbol;Acc:HGNC:24812]",{"v":0.880414596008085,"d":"0.88"},{"v":0.462746998736736,"d":"0.46"},{"v":1.90258304950988,"d":"1.90"},{"v":0.927959430076257,"d":"0.93"},{"v":0.155299809240955,"d":"0.16"},{"v":0.941801924237902,"d":"0.94"},"up","no"]
["ENSG00000152684","PELO","ENST00000274311","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0016787(hydrolase activity);GO:0051301(cell division);GO:0090305(nucleic acid phosphodiester bond hydrolysis);GO:0005515(protein binding);GO:0007049(cell cycle);GO:0004519(endonuclease activity);GO:0004518(nuclease activity);GO:0043022(ribosome binding);GO:0006412(translation);GO:0007492(endoderm development);GO:0008283(cell proliferation);GO:0019827(stem cell population maintenance);GO:0030513(positive regulation of BMP signaling pathway);GO:0032790(ribosome disassembly);GO:0051276(chromosome organization);GO:0060231(mesenchymal to epithelial transition);GO:0070481(nuclear-transcribed mRNA catabolic process, non-stop decay);GO:0070651(nonfunctional rRNA decay);GO:0070966(nuclear-transcribed mRNA catabolic process, no-go decay);GO:0071025(RNA surveillance)","03015(mRNA surveillance pathway)","K06965","NA","pelota mRNA surveillance and ribosome rescue factor [Source:HGNC Symbol;Acc:HGNC:8829]",{"v":1.078746,"d":"1.08"},{"v":2.12177,"d":"2.12"},{"v":0.508417971787706,"d":"0.51"},{"v":-0.975913066608339,"d":"-0.98"},{"v":0.155420006650588,"d":"0.16"},{"v":0.941801924237902,"d":"0.94"},"down","no"]
["ENSG00000162642","C1orf52","ENST00000294661;ENST00000471115;ENST00000493514","GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005634(nucleus)","NA","NA","NA","chromosome 1 open reading frame 52 [Source:HGNC Symbol;Acc:HGNC:24871]",{"v":0.966880954385965,"d":"0.97"},{"v":1.9045354119883,"d":"1.90"},{"v":0.507672867776483,"d":"0.51"},{"v":-0.978028936593113,"d":"-0.98"},{"v":0.155482352769113,"d":"0.16"},{"v":0.941801924237902,"d":"0.94"},"down","no"]
["MSTRG.15115","MAN1B1-AS1","ENST00000596585","NA","NA","NA","NA","MAN1B1 antisense RNA 1 (head to head) [Source:HGNC Symbol;Acc:HGNC:48715]",{"v":0.727097,"d":"0.73"},{"v":0.365332,"d":"0.37"},{"v":1.99023627823459,"d":"1.99"},{"v":0.992939715795183,"d":"0.99"},{"v":0.155599874068665,"d":"0.16"},{"v":0.941801924237902,"d":"0.94"},"up","no"]
["ENSG00000197024","ZNF398","ENST00000475153;ENST00000426851;ENST00000483892;ENST00000485111;ENST00000491174","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0005622(intracellular);GO:0005515(protein binding);GO:0045893(positive regulation of transcription, DNA-templated);GO:0045893(positive regulation of transcription, DNA-templated)","NA","NA","NA","zinc finger protein 398 [Source:HGNC Symbol;Acc:HGNC:18373]",{"v":0.9695960228439,"d":"0.97"},{"v":1.90766145671246,"d":"1.91"},{"v":0.508264199306537,"d":"0.51"},{"v":-0.976349479882825,"d":"-0.98"},{"v":0.155694961725989,"d":"0.16"},{"v":0.941801924237902,"d":"0.94"},"down","no"]
["MSTRG.15201","PRDX4","ENST00000379341;ENST00000379349;ENST00000439422","GO:0005623(cell);GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0045454(cell redox homeostasis);GO:0098869(cellular oxidant detoxification);GO:0016209(antioxidant activity);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0004601(peroxidase activity);GO:0051920(peroxiredoxin activity);GO:0070062(extracellular exosome);GO:0043312(neutrophil degranulation);GO:0034774(secretory granule lumen);GO:1904813(ficolin-1-rich granule lumen);GO:0007252(I-kappaB phosphorylation);GO:0008379(thioredoxin peroxidase activity);GO:0042803(protein homodimerization activity);GO:0007283(spermatogenesis);GO:0008584(male gonad development);GO:0019471(4-hydroxyproline metabolic process);GO:0022417(protein maturation by protein folding);GO:0030198(extracellular matrix organization);GO:0072593(reactive oxygen species metabolic process);GO:2000255(negative regulation of male germ cell proliferation);GO:0005615(extracellular space);GO:0005739(mitochondrion);GO:0005783(endoplasmic reticulum);GO:0005790(smooth endoplasmic reticulum);GO:0005829(cytosol);GO:0005829(cytosol)","NA","NA","NA","peroxiredoxin 4 [Source:HGNC Symbol;Acc:HGNC:17169]",{"v":1.14367733193277,"d":"1.14"},{"v":2.26507919117647,"d":"2.27"},{"v":0.50491715097111,"d":"0.50"},{"v":-0.985881411357092,"d":"-0.99"},{"v":0.155757154646998,"d":"0.16"},{"v":0.941801924237902,"d":"0.94"},"down","no"]
["MSTRG.13098","PTP4A1","ENST00000370651;ENST00000627002;ENST00000473334;ENST00000626021","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0016787(hydrolase activity);GO:0008138(protein tyrosine/serine/threonine phosphatase activity);GO:0016791(phosphatase activity);GO:0016311(dephosphorylation);GO:0035335(peptidyl-tyrosine dephosphorylation);GO:0005783(endoplasmic reticulum);GO:0005886(plasma membrane);GO:0004721(phosphoprotein phosphatase activity);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0007049(cell cycle);GO:0007275(multicellular organism development);GO:0006470(protein dephosphorylation);GO:0004725(protein tyrosine phosphatase activity);GO:0030335(positive regulation of cell migration);GO:0005634(nucleus);GO:0005819(spindle);GO:0005768(endosome);GO:0070062(extracellular exosome);GO:0005769(early endosome);GO:0009898(cytoplasmic side of plasma membrane);GO:0009898(cytoplasmic side of plasma membrane)","NA","NA","NA","protein tyrosine phosphatase type IVA, member 1 [Source:HGNC Symbol;Acc:HGNC:9634]",{"v":3.5140462191461,"d":"3.51"},{"v":6.85877928118746,"d":"6.86"},{"v":0.512342805487934,"d":"0.51"},{"v":-0.96481866301034,"d":"-0.96"},{"v":0.155762261872997,"d":"0.16"},{"v":0.941801924237902,"d":"0.94"},"down","no"]
["ENSG00000173848","NET1","ENST00000380359;ENST00000355029;ENST00000465087;ENST00000486354","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0035556(intracellular signal transduction);GO:0005089(Rho guanyl-nucleotide exchange factor activity);GO:0035023(regulation of Rho protein signal transduction);GO:0043547(positive regulation of GTPase activity);GO:0005515(protein binding);GO:0005085(guanyl-nucleotide exchange factor activity);GO:0005829(cytosol);GO:0051056(regulation of small GTPase mediated signal transduction);GO:0043065(positive regulation of apoptotic process);GO:0001558(regulation of cell growth);GO:0007165(signal transduction);GO:0071479(cellular response to ionizing radiation);GO:0070301(cellular response to hydrogen peroxide);GO:0017049(GTP-Rho binding);GO:0051451(myoblast migration);GO:1900026(positive regulation of substrate adhesion-dependent cell spreading);GO:0005886(plasma membrane);GO:0005622(intracellular);GO:0005622(intracellular)","NA","NA","NA","neuroepithelial cell transforming 1 [Source:HGNC Symbol;Acc:HGNC:14592]",{"v":1.3188063691018,"d":"1.32"},{"v":0.693901678323353,"d":"0.69"},{"v":1.90056662247651,"d":"1.90"},{"v":0.926429598328969,"d":"0.93"},{"v":0.155884925446635,"d":"0.16"},{"v":0.941801924237902,"d":"0.94"},"up","no"]
["MSTRG.3327","AC004241.1","ENST00000547799;ENST00000552133;ENST00000621159;ENST00000552502;ENST00000553045","NA","NA","NA","NA",null,{"v":0.144507488097937,"d":"0.14"},{"v":0.298582567218318,"d":"0.30"},{"v":0.483978316095982,"d":"0.48"},{"v":-1.04698568367175,"d":"-1.05"},{"v":0.156062475824296,"d":"0.16"},{"v":0.941801924237902,"d":"0.94"},"down","no"]
["MSTRG.1966","MXI1","ENST00000332674;ENST00000239007;ENST00000460667;ENST00000393134;ENST00000369612;ENST00000484030;ENST00000485566;ENST00000453116;ENST00000442296;ENST00000361248","GO:0005634(nucleus);GO:0005730(nucleolus);GO:0005829(cytosol);GO:0046983(protein dimerization activity);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0042994(cytoplasmic sequestering of transcription factor);GO:0003714(transcription corepressor activity);GO:0000977(RNA polymerase II regulatory region sequence-specific DNA binding);GO:0090575(RNA polymerase II transcription factor complex);GO:0008285(negative regulation of cell proliferation);GO:0001227(transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding);GO:0001227(transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding)","NA","NA","NA","MAX interactor 1, dimerization protein [Source:HGNC Symbol;Acc:HGNC:7534]",{"v":39.4874558741046,"d":"39.49"},{"v":21.0364832871717,"d":"21.04"},{"v":1.87709396742109,"d":"1.88"},{"v":0.908500873364913,"d":"0.91"},{"v":0.156196597467133,"d":"0.16"},{"v":0.941801924237902,"d":"0.94"},"up","no"]
["MSTRG.3724","BRAP","ENST00000419234;ENST00000547043","GO:0003676(nucleic acid binding);GO:0005737(cytoplasm);GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0005829(cytosol);GO:0016740(transferase activity);GO:0016567(protein ubiquitination);GO:0031965(nuclear membrane);GO:0005515(protein binding);GO:0042802(identical protein binding);GO:0061630(ubiquitin protein ligase activity);GO:0000165(MAPK cascade);GO:0004842(ubiquitin-protein transferase activity);GO:0009968(negative regulation of signal transduction);GO:0000151(ubiquitin ligase complex);GO:0008139(nuclear localization sequence binding);GO:0007265(Ras protein signal transduction);GO:0007265(Ras protein signal transduction)","04014(Ras signaling pathway);04014(Ras signaling pathway)","K10632","EC:2.3.2.27","BRCA1 associated protein [Source:HGNC Symbol;Acc:HGNC:1099]",{"v":1.80115553585147,"d":"1.80"},{"v":3.52490531391379,"d":"3.52"},{"v":0.510979835044591,"d":"0.51"},{"v":-0.968661736122102,"d":"-0.97"},{"v":0.156278858085693,"d":"0.16"},{"v":0.941801924237902,"d":"0.94"},"down","no"]
["ENSG00000093144","ECHDC1","ENST00000454859;ENST00000368291;ENST00000461239;ENST00000474240;ENST00000454591;ENST00000488087;ENST00000474289;ENST00000526299;ENST00000368292;ENST00000417628;ENST00000430841;ENST00000368287;ENST00000475319;ENST00000368289;ENST00000534442;ENST00000479525;ENST00000531967;ENST00000436638","GO:0005737(cytoplasm);GO:0003824(catalytic activity);GO:0016829(lyase activity);GO:0008152(metabolic process);GO:0005829(cytosol);GO:0016831(carboxy-lyase activity);GO:0005739(mitochondrion);GO:0070062(extracellular exosome);GO:0006635(fatty acid beta-oxidation);GO:0004300(enoyl-CoA hydratase activity);GO:0004492(methylmalonyl-CoA decarboxylase activity);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016021(integral component of membrane)","00640(Propanoate metabolism);00640(Propanoate metabolism)","K18426","EC:4.1.1.94;EC:4.1.1.41","ethylmalonyl-CoA decarboxylase 1 [Source:HGNC Symbol;Acc:HGNC:21489]",{"v":2.24663066731243,"d":"2.25"},{"v":1.18626316484678,"d":"1.19"},{"v":1.89387206303637,"d":"1.89"},{"v":0.921338875549115,"d":"0.92"},{"v":0.156356351870085,"d":"0.16"},{"v":0.941801924237902,"d":"0.94"},"up","no"]
["MSTRG.10663","TSEN2","ENST00000473755;ENST00000415684;ENST00000444864;ENST00000402228;ENST00000455118;ENST00000475595;ENST00000284995;ENST00000446004;ENST00000454502;ENST00000412698","GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0005813(centrosome);GO:0000213(tRNA-intron endonuclease activity);GO:0006388(tRNA splicing, via endonucleolytic cleavage and ligation);GO:0090501(RNA phosphodiester bond hydrolysis);GO:0090502(RNA phosphodiester bond hydrolysis, endonucleolytic);GO:0000214(tRNA-intron endonuclease complex);GO:0006397(mRNA processing);GO:0005634(nucleus);GO:0008033(tRNA processing);GO:0016829(lyase activity);GO:0005515(protein binding);GO:0005730(nucleolus);GO:0000379(tRNA-type intron splice site recognition and cleavage);GO:0090305(nucleic acid phosphodiester bond hydrolysis);GO:0004519(endonuclease activity);GO:0004519(endonuclease activity)","NA","NA","NA","tRNA splicing endonuclease subunit 2 [Source:HGNC Symbol;Acc:HGNC:28422]",{"v":0.502013768660667,"d":"0.50"},{"v":0.258024599964708,"d":"0.26"},{"v":1.94560429016974,"d":"1.95"},{"v":0.960218315123467,"d":"0.96"},{"v":0.156391478780021,"d":"0.16"},{"v":0.941801924237902,"d":"0.94"},"up","no"]
["ENSG00000167393","PPP2R3B","ENST00000390665;ENST00000484364;ENST00000468169;ENST00000477636;ENST00000496630;ENST00000477110;ENST00000445792;ENST00000381625;ENST00000479438","GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0005509(calcium ion binding);GO:0050790(regulation of catalytic activity);GO:0005515(protein binding);GO:0000159(protein phosphatase type 2A complex);GO:0005654(nucleoplasm);GO:0006470(protein dephosphorylation);GO:0004722(protein serine/threonine phosphatase activity);GO:0007050(cell cycle arrest);GO:0019888(protein phosphatase regulator activity);GO:0004721(phosphoprotein phosphatase activity);GO:0004721(phosphoprotein phosphatase activity)","03015(mRNA surveillance pathway);04071(Sphingolipid signaling pathway);04151(PI3K-Akt signaling pathway);04152(AMPK signaling pathway);04261(Adrenergic signaling in cardiomyocytes);04728(Dopaminergic synapse);05165(Human papillomavirus infection);05165(Human papillomavirus infection)","K11583","NA","protein phosphatase 2 regulatory subunit B''beta [Source:HGNC Symbol;Acc:HGNC:13417]",{"v":0.593772765391015,"d":"0.59"},{"v":0.313156051802551,"d":"0.31"},{"v":1.89609225807137,"d":"1.90"},{"v":0.923029163088426,"d":"0.92"},{"v":0.156492075802877,"d":"0.16"},{"v":0.941801924237902,"d":"0.94"},"up","no"]
["MSTRG.9521","PASK","ENST00000358649;ENST00000489256;ENST00000405260;ENST00000403638;ENST00000452907;ENST00000459710;ENST00000485940;ENST00000493544;ENST00000234040;ENST00000544142;ENST00000472072","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0005829(cytosol);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0005515(protein binding);GO:0045727(positive regulation of translation);GO:0008289(lipid binding);GO:0035091(phosphatidylinositol binding);GO:0046777(protein autophosphorylation);GO:2000505(regulation of energy homeostasis);GO:0070092(regulation of glucagon secretion);GO:0045719(negative regulation of glycogen biosynthetic process);GO:0043576(regulation of respiratory gaseous exchange);GO:0043576(regulation of respiratory gaseous exchange)","NA","NA","NA","PAS domain containing serine/threonine kinase [Source:HGNC Symbol;Acc:HGNC:17270]",{"v":1.98463891063073,"d":"1.98"},{"v":1.05373536430844,"d":"1.05"},{"v":1.8834320056566,"d":"1.88"},{"v":0.913363951059293,"d":"0.91"},{"v":0.15662047080668,"d":"0.16"},{"v":0.941801924237902,"d":"0.94"},"up","no"]
["ENSG00000157895","C12orf43","ENST00000288757;ENST00000546272;ENST00000445832;ENST00000502891;ENST00000538296;ENST00000537817;ENST00000508193","GO:0005515(protein binding);GO:0005515(protein binding)","NA","NA","NA","chromosome 12 open reading frame 43 [Source:HGNC Symbol;Acc:HGNC:25719]",{"v":1.06987202964169,"d":"1.07"},{"v":0.56548677752443,"d":"0.57"},{"v":1.89194879909543,"d":"1.89"},{"v":0.919873046240405,"d":"0.92"},{"v":0.156759083402424,"d":"0.16"},{"v":0.941801924237902,"d":"0.94"},"up","no"]
["ENSG00000226200","SGMS1-AS1","ENST00000443374;ENST00000609579","NA","NA","NA","NA","SGMS1 antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:49683]",{"v":0.225142866344606,"d":"0.23"},{"v":0.116248172624799,"d":"0.12"},{"v":1.93674327312889,"d":"1.94"},{"v":0.953632728783363,"d":"0.95"},{"v":0.157101442865205,"d":"0.16"},{"v":0.941801924237902,"d":"0.94"},"up","no"]
["MSTRG.4557","AC007686.3","ENST00000619017","NA","NA","NA","NA",null,{"v":0.758852,"d":"0.76"},{"v":0.394875,"d":"0.39"},{"v":1.92175245330801,"d":"1.92"},{"v":0.942422510208588,"d":"0.94"},{"v":0.158639897227288,"d":"0.16"},{"v":0.943610824607541,"d":"0.94"},"up","no"]
["MSTRG.797","RAP1A","MSTRG.797.6;ENST00000369709;ENST00000494982;MSTRG.797.2;ENST00000356415;ENST00000433097","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0015031(protein transport);GO:0005525(GTP binding);GO:0000166(nucleotide binding);GO:0007165(signal transduction);GO:0003924(GTPase activity);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0048471(perinuclear region of cytoplasm);GO:0030054(cell junction);GO:0007399(nervous system development);GO:0005768(endosome);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0043547(positive regulation of GTPase activity);GO:0005769(early endosome);GO:0005770(late endosome);GO:0043312(neutrophil degranulation);GO:0035579(specific granule membrane);GO:0070374(positive regulation of ERK1 and ERK2 cascade);GO:0032403(protein complex binding);GO:0061028(establishment of endothelial barrier);GO:0008565(protein transporter activity);GO:0050796(regulation of insulin secretion);GO:0045860(positive regulation of protein kinase activity);GO:0071320(cellular response to cAMP);GO:0010976(positive regulation of neuron projection development);GO:0017034(Rap guanyl-nucleotide exchange factor activity);GO:0032486(Rap protein signal transduction);GO:0000186(activation of MAPKK activity);GO:0038180(nerve growth factor signaling pathway);GO:1990090(cellular response to nerve growth factor stimulus);GO:2001214(positive regulation of vasculogenesis);GO:1901888(regulation of cell junction assembly);GO:0017016(Ras GTPase binding);GO:0007264(small GTPase mediated signal transduction);GO:0009743(response to carbohydrate);GO:0032966(negative regulation of collagen biosynthetic process);GO:0035690(cellular response to drug);GO:0046326(positive regulation of glucose import);GO:0071333(cellular response to glucose stimulus);GO:0071407(cellular response to organic cyclic compound);GO:0097327(response to antineoplastic agent);GO:0097421(liver regeneration);GO:1905451(positive regulation of Fc-gamma receptor signaling pathway involved in phagocytosis);GO:2000301(negative regulation of synaptic vesicle exocytosis);GO:0032045(guanyl-nucleotide exchange factor complex);GO:0043005(neuron projection);GO:0043209(myelin sheath);GO:0045335(phagocytic vesicle);GO:0045335(phagocytic vesicle)","04014(Ras signaling pathway);04015(Rap1 signaling pathway);04010(MAPK signaling pathway);04024(cAMP signaling pathway);04510(Focal adhesion);04530(Tight junction);04611(Platelet activation);04670(Leukocyte transendothelial migration);04062(Chemokine signaling pathway);04972(Pancreatic secretion);04720(Long-term potentiation);04722(Neurotrophin signaling pathway);05211(Renal cell carcinoma);05211(Renal cell carcinoma)","K04353","NA","RAP1A, member of RAS oncogene family [Source:HGNC Symbol;Acc:HGNC:9855]",{"v":4.60025899838013,"d":"4.60"},{"v":8.91733784395248,"d":"8.92"},{"v":0.515878065727869,"d":"0.52"},{"v":-0.954897988071818,"d":"-0.95"},{"v":0.159645827403853,"d":"0.16"},{"v":0.946555910190643,"d":"0.95"},"down","no"]
["ENSG00000135002","RFK","ENST00000376736;ENST00000490113;ENST00000479197","GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0005829(cytosol);GO:0008531(riboflavin kinase activity);GO:0009231(riboflavin biosynthetic process);GO:0006915(apoptotic process);GO:0006771(riboflavin metabolic process);GO:0009398(FMN biosynthetic process);GO:0033864(positive regulation of NAD(P)H oxidase activity);GO:0072593(reactive oxygen species metabolic process);GO:0005739(mitochondrion);GO:0005739(mitochondrion)","00740(Riboflavin metabolism);00740(Riboflavin metabolism)","K00861","EC:2.7.1.26","riboflavin kinase [Source:HGNC Symbol;Acc:HGNC:30324]",{"v":0.826824995615166,"d":"0.83"},{"v":1.61685973794171,"d":"1.62"},{"v":0.511377070139509,"d":"0.51"},{"v":-0.967540622492528,"d":"-0.97"},{"v":0.161209277073813,"d":"0.16"},{"v":0.948077878478197,"d":"0.95"},"down","no"]
["MSTRG.161","AGTRAP","ENST00000376629;ENST00000314340;ENST00000494437;ENST00000476512;ENST00000376627;ENST00000476309;ENST00000376637;ENST00000514733;ENST00000452018;ENST00000510878;ENST00000400895;ENST00000471765;ENST00000491346;ENST00000513739","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0043231(intracellular membrane-bounded organelle);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0005794(Golgi apparatus);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005515(protein binding);GO:0000139(Golgi membrane);GO:0030659(cytoplasmic vesicle membrane);GO:0031410(cytoplasmic vesicle);GO:0038166(angiotensin-activated signaling pathway);GO:0004945(angiotensin type II receptor activity);GO:0001666(response to hypoxia);GO:0008217(regulation of blood pressure);GO:0005886(plasma membrane);GO:0005938(cell cortex);GO:0005938(cell cortex)","NA","NA","NA","angiotensin II receptor associated protein [Source:HGNC Symbol;Acc:HGNC:13539]",{"v":12.5270692135524,"d":"12.53"},{"v":24.195646486653,"d":"24.20"},{"v":0.517740628276359,"d":"0.52"},{"v":-0.949698560708287,"d":"-0.95"},{"v":0.16228836632431,"d":"0.16"},{"v":0.950986134928149,"d":"0.95"},"down","no"]
["MSTRG.9678","MAP1LC3A","ENST00000360668;ENST00000397709;ENST00000476428","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005829(cytosol);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0005874(microtubule);GO:0006914(autophagy);GO:0031410(cytoplasmic vesicle);GO:0008429(phosphatidylethanolamine binding);GO:0000045(autophagosome assembly);GO:0000421(autophagosome membrane);GO:0006995(cellular response to nitrogen starvation);GO:0012505(endomembrane system);GO:0009267(cellular response to starvation);GO:0031625(ubiquitin protein ligase binding);GO:0005776(autophagosome);GO:0031090(organelle membrane);GO:0005543(phospholipid binding);GO:0016236(macroautophagy);GO:0097352(autophagosome maturation);GO:0044754(autolysosome);GO:0000422(mitophagy);GO:0010040(response to iron(II) ion);GO:0010288(response to lead ion);GO:0031667(response to nutrient levels);GO:0034198(cellular response to amino acid starvation);GO:0043278(response to morphine);GO:0070301(cellular response to hydrogen peroxide);GO:0071280(cellular response to copper ion);GO:0005770(late endosome);GO:0005770(late endosome)","04216(Ferroptosis);04216(Ferroptosis)","K10435","NA","microtubule associated protein 1 light chain 3 alpha [Source:HGNC Symbol;Acc:HGNC:6838]",{"v":0.827220879114643,"d":"0.83"},{"v":1.64465101021566,"d":"1.64"},{"v":0.502976542729373,"d":"0.50"},{"v":-0.991436976123221,"d":"-0.99"},{"v":0.164042575910443,"d":"0.16"},{"v":0.951612588013184,"d":"0.95"},"down","no"]
["MSTRG.12396","NDUFA2","ENST00000252102;ENST00000510680;ENST00000512088;ENST00000502960","GO:0016020(membrane);GO:0055114(oxidation-reduction process);GO:0005743(mitochondrial inner membrane);GO:0005739(mitochondrion);GO:0070469(respiratory chain);GO:0031966(mitochondrial membrane);GO:0032981(mitochondrial respiratory chain complex I assembly);GO:0008137(NADH dehydrogenase (ubiquinone) activity);GO:0006120(mitochondrial electron transport, NADH to ubiquinone);GO:0005747(mitochondrial respiratory chain complex I);GO:0005747(mitochondrial respiratory chain complex I)","00190(Oxidative phosphorylation);04723(Retrograde endocannabinoid signaling);05010(Alzheimer's disease);05012(Parkinson's disease);05016(Huntington's disease);04932(Non-alcoholic fatty liver disease (NAFLD));04932(Non-alcoholic fatty liver disease (NAFLD))","K03946","NA","NADH:ubiquinone oxidoreductase subunit A2 [Source:HGNC Symbol;Acc:HGNC:7685]",{"v":6.24642751680108,"d":"6.25"},{"v":3.34374811491935,"d":"3.34"},{"v":1.86809152547417,"d":"1.87"},{"v":0.901565140332895,"d":"0.90"},{"v":0.165543973886038,"d":"0.17"},{"v":0.952960693061563,"d":"0.95"},"up","no"]
["MSTRG.6856","DHX8","ENST00000262415;ENST00000587044;ENST00000592258;ENST00000540306;ENST00000589898;ENST00000587574","GO:0003676(nucleic acid binding);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0005654(nucleoplasm);GO:0016787(hydrolase activity);GO:0016604(nuclear body);GO:0004386(helicase activity);GO:0003723(RNA binding);GO:0006397(mRNA processing);GO:0008380(RNA splicing);GO:0005634(nucleus);GO:0005515(protein binding);GO:0005681(spliceosomal complex);GO:0042802(identical protein binding);GO:0005737(cytoplasm);GO:0000398(mRNA splicing, via spliceosome);GO:0004004(ATP-dependent RNA helicase activity);GO:0006396(RNA processing);GO:0071013(catalytic step 2 spliceosome);GO:0071013(catalytic step 2 spliceosome)","03040(Spliceosome);03040(Spliceosome)","K12818","EC:3.6.4.13","DEAH-box helicase 8 [Source:HGNC Symbol;Acc:HGNC:2749]",{"v":2.30064239109869,"d":"2.30"},{"v":4.42175473597076,"d":"4.42"},{"v":0.520300769371733,"d":"0.52"},{"v":-0.942582254249745,"d":"-0.94"},{"v":0.165838672842392,"d":"0.17"},{"v":0.953220269106305,"d":"0.95"},"down","no"]
["ENSG00000161692","DBF4B","ENST00000315005;ENST00000527862;ENST00000528766;ENST00000528353;ENST00000525140;ENST00000532789;ENST00000393547;ENST00000526915","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0043231(intracellular membrane-bounded organelle);GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0005515(protein binding);GO:0016235(aggresome);GO:0007049(cell cycle);GO:0005654(nucleoplasm);GO:0032147(activation of protein kinase activity);GO:0019901(protein kinase binding);GO:0008284(positive regulation of cell proliferation);GO:0010571(positive regulation of nuclear cell cycle DNA replication);GO:0010971(positive regulation of G2/M transition of mitotic cell cycle);GO:0030295(protein kinase activator activity);GO:0030295(protein kinase activator activity)","NA","NA","NA","DBF4 zinc finger B [Source:HGNC Symbol;Acc:HGNC:17883]",{"v":0.280060673103834,"d":"0.28"},{"v":0.145673939546599,"d":"0.15"},{"v":1.92251732860047,"d":"1.92"},{"v":0.942996601970351,"d":"0.94"},{"v":0.167910296894298,"d":"0.17"},{"v":0.955956268451435,"d":"0.96"},"up","no"]
["ENSG00000171827","ZNF570","ENST00000330173;ENST00000588644;ENST00000589725;ENST00000590664;ENST00000591380;ENST00000587363","GO:0003676(nucleic acid binding);GO:0046872(metal ion binding);GO:0006355(regulation of transcription, DNA-templated);GO:0005622(intracellular);GO:0005634(nucleus);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0003677(DNA binding)","NA","NA","NA","zinc finger protein 570 [Source:HGNC Symbol;Acc:HGNC:26416]",{"v":0.482089556195965,"d":"0.48"},{"v":0.257970174351585,"d":"0.26"},{"v":1.86878020843964,"d":"1.87"},{"v":0.902096900361613,"d":"0.90"},{"v":0.169137541891863,"d":"0.17"},{"v":0.958994591982864,"d":"0.96"},"up","no"]
["ENSG00000010539","ZNF200","ENST00000431561;ENST00000414144;ENST00000575948;ENST00000396870;ENST00000575630;ENST00000575285;ENST00000575617;ENST00000396871","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003674(molecular_function);GO:0008150(biological_process);GO:0008150(biological_process)","NA","NA","NA","zinc finger protein 200 [Source:HGNC Symbol;Acc:HGNC:12993]",{"v":0.808697636969859,"d":"0.81"},{"v":1.54862349133102,"d":"1.55"},{"v":0.522204164857912,"d":"0.52"},{"v":-0.937314130925052,"d":"-0.94"},{"v":0.171477234841277,"d":"0.17"},{"v":0.963834077811061,"d":"0.96"},"down","no"]
["MSTRG.8772","RAB1A","ENST00000409784;ENST00000398529;ENST00000409892;ENST00000494188;ENST00000409751","GO:0006810(transport);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0015031(protein transport);GO:0005525(GTP binding);GO:0000166(nucleotide binding);GO:0003924(GTPase activity);GO:0005794(Golgi apparatus);GO:0005829(cytosol);GO:0005783(endoplasmic reticulum);GO:0005515(protein binding);GO:0042470(melanosome);GO:0006914(autophagy);GO:0042742(defense response to bacterium);GO:0016192(vesicle-mediated transport);GO:0005768(endosome);GO:0045296(cadherin binding);GO:0006897(endocytosis);GO:0070062(extracellular exosome);GO:0000045(autophagosome assembly);GO:0006890(retrograde vesicle-mediated transport, Golgi to ER);GO:0061024(membrane organization);GO:0043687(post-translational protein modification);GO:0005769(early endosome);GO:0006888(ER to Golgi vesicle-mediated transport);GO:0005789(endoplasmic reticulum membrane);GO:0016477(cell migration);GO:0000139(Golgi membrane);GO:0048208(COPII vesicle coating);GO:0047496(vesicle transport along microtubule);GO:0007030(Golgi organization);GO:0030658(transport vesicle membrane);GO:0090110(cargo loading into COPII-coated vesicle);GO:0072606(interleukin-8 secretion);GO:1904668(positive regulation of ubiquitin protein ligase activity);GO:0019068(virion assembly);GO:0030252(growth hormone secretion);GO:1903020(positive regulation of glycoprotein metabolic process);GO:0032402(melanosome transport);GO:0034446(substrate adhesion-dependent cell spreading);GO:0034446(substrate adhesion-dependent cell spreading)","05134(Legionellosis);05134(Legionellosis)","K07874","NA","RAB1A, member RAS oncogene family [Source:HGNC Symbol;Acc:HGNC:9758]",{"v":7.40015948017621,"d":"7.40"},{"v":14.0940586702813,"d":"14.09"},{"v":0.525055248690015,"d":"0.53"},{"v":-0.929458857218341,"d":"-0.93"},{"v":0.171741499767345,"d":"0.17"},{"v":0.963834077811061,"d":"0.96"},"down","no"]
["MSTRG.471","PPIH","ENST00000304979;MSTRG.471.1;ENST00000372550;ENST00000436387;ENST00000372549;ENST00000440068;ENST00000461351","GO:0005737(cytoplasm);GO:0006397(mRNA processing);GO:0008380(RNA splicing);GO:0005634(nucleus);GO:0016607(nuclear speck);GO:0016853(isomerase activity);GO:0003755(peptidyl-prolyl cis-trans isomerase activity);GO:0000413(protein peptidyl-prolyl isomerization);GO:0006457(protein folding);GO:0005515(protein binding);GO:0005681(spliceosomal complex);GO:0005654(nucleoplasm);GO:0006461(protein complex assembly);GO:0000398(mRNA splicing, via spliceosome);GO:0071001(U4/U6 snRNP);GO:0016018(cyclosporin A binding);GO:0043021(ribonucleoprotein complex binding);GO:0045070(positive regulation of viral genome replication);GO:0046540(U4/U6 x U5 tri-snRNP complex);GO:0046540(U4/U6 x U5 tri-snRNP complex)","03040(Spliceosome);03040(Spliceosome)","K09567","EC:5.2.1.8","peptidylprolyl isomerase H [Source:HGNC Symbol;Acc:HGNC:14651]",{"v":10.5246364421461,"d":"10.52"},{"v":5.72555637104072,"d":"5.73"},{"v":1.83818580415672,"d":"1.84"},{"v":0.878282601875752,"d":"0.88"},{"v":0.173724703362292,"d":"0.17"},{"v":0.964604874557238,"d":"0.96"},"up","no"]
["MSTRG.1423","EPHX1","MSTRG.1423.1;ENST00000272167;ENST00000614058;ENST00000467015;ENST00000448202","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016787(hydrolase activity);GO:0003824(catalytic activity);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0043231(intracellular membrane-bounded organelle);GO:0006805(xenobiotic metabolic process);GO:0031090(organelle membrane);GO:0009636(response to toxic substance);GO:0004301(epoxide hydrolase activity);GO:0033961(cis-stilbene-oxide hydrolase activity);GO:0019439(aromatic compound catabolic process);GO:0019899(enzyme binding);GO:0001889(liver development);GO:0006725(cellular aromatic compound metabolic process);GO:0014070(response to organic cyclic compound);GO:0034312(diol biosynthetic process);GO:0071310(cellular response to organic substance);GO:0071385(cellular response to glucocorticoid stimulus);GO:0005886(plasma membrane);GO:0005886(plasma membrane)","00980(Metabolism of xenobiotics by cytochrome P450);04976(Bile secretion);05204(Chemical carcinogenesis);05204(Chemical carcinogenesis)","K01253","EC:3.3.2.9","epoxide hydrolase 1 [Source:HGNC Symbol;Acc:HGNC:3401]",{"v":9.748490005,"d":"9.75"},{"v":5.3307976625,"d":"5.33"},{"v":1.82871131530215,"d":"1.83"},{"v":0.87082734580625,"d":"0.87"},{"v":0.174150159184426,"d":"0.17"},{"v":0.965078792866479,"d":"0.97"},"up","no"]
["ENSG00000145414","NAF1","ENST00000274054;ENST00000509434;ENST00000502973;ENST00000422287;ENST00000509884;ENST00000509232","GO:0001522(pseudouridine synthesis);GO:0042254(ribosome biogenesis);GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0030529(intracellular ribonucleoprotein complex);GO:0005515(protein binding);GO:0006364(rRNA processing);GO:0005732(small nucleolar ribonucleoprotein complex);GO:0032212(positive regulation of telomere maintenance via telomerase);GO:0051973(positive regulation of telomerase activity);GO:0070034(telomerase RNA binding);GO:0090669(telomerase RNA stabilization);GO:1904874(positive regulation of telomerase RNA localization to Cajal body);GO:1905323(telomerase holoenzyme complex assembly);GO:1904358(positive regulation of telomere maintenance via telomere lengthening);GO:0000454(snoRNA guided rRNA pseudouridine synthesis);GO:0000493(box H/ACA snoRNP assembly);GO:0043489(RNA stabilization);GO:0043489(RNA stabilization)","NA","NA","NA","nuclear assembly factor 1 ribonucleoprotein [Source:HGNC Symbol;Acc:HGNC:25126]",{"v":0.157495704034942,"d":"0.16"},{"v":0.318255162853577,"d":"0.32"},{"v":0.494872424449569,"d":"0.49"},{"v":-1.0148714410806,"d":"-1.01"},{"v":0.17663153330648,"d":"0.18"},{"v":0.968635149897063,"d":"0.97"},"down","no"]
["ENSG00000115084","SLC35F5","ENST00000245680;ENST00000469314;ENST00000498768;ENST00000485214;ENST00000409106;ENST00000459683;ENST00000409342;ENST00000469702;ENST00000447673;ENST00000638402","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016021(integral component of membrane)","NA","NA","NA","solute carrier family 35 member F5 [Source:HGNC Symbol;Acc:HGNC:23617]",{"v":0.596860568703828,"d":"0.60"},{"v":1.14000173364674,"d":"1.14"},{"v":0.52356110617002,"d":"0.52"},{"v":-0.933570167237092,"d":"-0.93"},{"v":0.178156056658869,"d":"0.18"},{"v":0.970748974790092,"d":"0.97"},"down","no"]
["ENSG00000136379","ABHD17C","ENST00000258884","GO:0016787(hydrolase activity)","NA","NA","NA","abhydrolase domain containing 17C [Source:HGNC Symbol;Acc:HGNC:26925]",{"v":0.641001996140061,"d":"0.64"},{"v":0.341392869037772,"d":"0.34"},{"v":1.87760804127734,"d":"1.88"},{"v":0.90889592565187,"d":"0.91"},{"v":0.178671176683658,"d":"0.18"},{"v":0.971796887815995,"d":"0.97"},"up","no"]
["MSTRG.923","GOLPH3L","ENST00000271732;ENST00000427665;ENST00000479757","GO:0016020(membrane);GO:0005794(Golgi apparatus);GO:0005515(protein binding);GO:0000139(Golgi membrane);GO:0008289(lipid binding);GO:0032580(Golgi cisterna membrane);GO:0005829(cytosol);GO:0070273(phosphatidylinositol-4-phosphate binding);GO:0005802(trans-Golgi network);GO:0043001(Golgi to plasma membrane protein transport);GO:0050714(positive regulation of protein secretion);GO:0006890(retrograde vesicle-mediated transport, Golgi to ER);GO:0007030(Golgi organization);GO:0032588(trans-Golgi network membrane);GO:0048194(Golgi vesicle budding);GO:0031985(Golgi cisterna);GO:0031985(Golgi cisterna)","NA","NA","NA","golgi phosphoprotein 3 like [Source:HGNC Symbol;Acc:HGNC:24882]",{"v":3.26807870501652,"d":"3.27"},{"v":1.79180490117152,"d":"1.79"},{"v":1.82390320669387,"d":"1.82"},{"v":0.867029168686826,"d":"0.87"},{"v":0.180784902290674,"d":"0.18"},{"v":0.974328911194028,"d":"0.97"},"up","no"]
["MSTRG.2065","IFITM3","ENST00000399808;ENST00000602735;ENST00000526811;ENST00000531688","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005765(lysosomal membrane);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0002376(immune system process);GO:0045087(innate immune response);GO:0005764(lysosome);GO:0009607(response to biotic stimulus);GO:0051607(defense response to virus);GO:0005768(endosome);GO:0031902(late endosome membrane);GO:0070062(extracellular exosome);GO:0009615(response to virus);GO:0045071(negative regulation of viral genome replication);GO:0006955(immune response);GO:0046597(negative regulation of viral entry into host cell);GO:0060337(type I interferon signaling pathway);GO:0035456(response to interferon-beta);GO:0034341(response to interferon-gamma);GO:0032897(negative regulation of viral transcription);GO:0035455(response to interferon-alpha);GO:0035455(response to interferon-alpha)","NA","NA","NA","interferon induced transmembrane protein 3 [Source:HGNC Symbol;Acc:HGNC:5414]",{"v":60.8167478998516,"d":"60.82"},{"v":114.050543235905,"d":"114.05"},{"v":0.533243824837,"d":"0.53"},{"v":-0.907132741173125,"d":"-0.91"},{"v":0.181356728319939,"d":"0.18"},{"v":0.974328911194028,"d":"0.97"},"down","no"]
["MSTRG.12582","DOK3","ENST00000357198;MSTRG.12582.1;MSTRG.12582.6;ENST00000510898;ENST00000501403;ENST00000509310;ENST00000377112;ENST00000510389;ENST00000512660;ENST00000500323;MSTRG.12582.3;ENST00000502885;ENST00000510380;ENST00000502380;ENST00000506493;ENST00000312943","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0005158(insulin receptor binding);GO:0043312(neutrophil degranulation);GO:0030667(secretory granule membrane);GO:0101003(ficolin-1-rich granule membrane);GO:0101003(ficolin-1-rich granule membrane)","NA","NA","NA","docking protein 3 [Source:HGNC Symbol;Acc:HGNC:24583]",{"v":24.2686621172914,"d":"24.27"},{"v":13.4536193800887,"d":"13.45"},{"v":1.80387607465757,"d":"1.80"},{"v":0.85110022960322,"d":"0.85"},{"v":0.183198125205395,"d":"0.18"},{"v":0.977270468943331,"d":"0.98"},"up","no"]
["MSTRG.10080","UBE2G2","ENST00000481546;ENST00000462569;ENST00000490450;ENST00000330942;ENST00000497630;ENST00000490091;ENST00000345496","GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0016740(transferase activity);GO:0016567(protein ubiquitination);GO:0005829(cytosol);GO:0005515(protein binding);GO:0031625(ubiquitin protein ligase binding);GO:0018279(protein N-linked glycosylation via asparagine);GO:0061630(ubiquitin protein ligase activity);GO:0061631(ubiquitin conjugating enzyme activity);GO:0035458(cellular response to interferon-beta);GO:0030433(ubiquitin-dependent ERAD pathway);GO:0004842(ubiquitin-protein transferase activity);GO:0070936(protein K48-linked ubiquitination);GO:0006511(ubiquitin-dependent protein catabolic process);GO:0044257(cellular protein catabolic process);GO:0042802(identical protein binding);GO:1904153(negative regulation of retrograde protein transport, ER to cytosol);GO:0005783(endoplasmic reticulum);GO:0005783(endoplasmic reticulum)","04141(Protein processing in endoplasmic reticulum);04120(Ubiquitin mediated proteolysis);05012(Parkinson's disease);05012(Parkinson's disease)","K04555","EC:2.3.2.23","ubiquitin conjugating enzyme E2 G2 [Source:HGNC Symbol;Acc:HGNC:12483]",{"v":5.05051633649161,"d":"5.05"},{"v":2.8033747717921,"d":"2.80"},{"v":1.80158442863599,"d":"1.80"},{"v":0.849266263155378,"d":"0.85"},{"v":0.184905947755125,"d":"0.18"},{"v":0.977270468943331,"d":"0.98"},"up","no"]
["MSTRG.187","SZRD1","ENST00000401088;ENST00000492354;ENST00000471507;ENST00000401089;ENST00000486763;ENST00000472351;ENST00000472461;ENST00000475078;ENST00000475554","NA","NA","NA","NA","SUZ RNA binding domain containing 1 [Source:HGNC Symbol;Acc:HGNC:30232]",{"v":8.97461319043606,"d":"8.97"},{"v":16.7574945793132,"d":"16.76"},{"v":0.535558173565817,"d":"0.54"},{"v":-0.900884802532572,"d":"-0.90"},{"v":0.185100632414378,"d":"0.19"},{"v":0.977270468943331,"d":"0.98"},"down","no"]
["ENSG00000136643","RPS6KC1","ENST00000366960;ENST00000491616;ENST00000614059;ENST00000543354;ENST00000615329;ENST00000468069;ENST00000543470","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0035091(phosphatidylinositol binding);GO:0005515(protein binding);GO:0005769(early endosome);GO:0007165(signal transduction);GO:0007165(signal transduction)","NA","NA","NA","ribosomal protein S6 kinase C1 [Source:HGNC Symbol;Acc:HGNC:10439]",{"v":0.964504471405493,"d":"0.96"},{"v":1.80603084329564,"d":"1.81"},{"v":0.534046511434693,"d":"0.53"},{"v":-0.904962699614871,"d":"-0.90"},{"v":0.187398289502171,"d":"0.19"},{"v":0.978302124958596,"d":"0.98"},"down","no"]
["MSTRG.6793","MSL1","ENST00000579565;ENST00000398532;ENST00000339569;ENST00000578648;ENST00000577454;ENST00000583127;ENST00000582884;ENST00000582920;ENST00000580086;ENST00000581246;ENST00000578826","GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0016569(covalent chromatin modification);GO:0043984(histone H4-K16 acetylation);GO:0072487(MSL complex);GO:0072487(MSL complex)","NA","NA","NA","male specific lethal 1 homolog [Source:HGNC Symbol;Acc:HGNC:27905]",{"v":6.42879620805732,"d":"6.43"},{"v":11.956263698932,"d":"11.96"},{"v":0.53769274164065,"d":"0.54"},{"v":-0.895146098203716,"d":"-0.90"},{"v":0.187555470156936,"d":"0.19"},{"v":0.978302124958596,"d":"0.98"},"down","no"]
["MSTRG.4292","KHNYN","ENST00000553935;MSTRG.4292.5;ENST00000251343;ENST00000556255;ENST00000556842;ENST00000554268;ENST00000556510","GO:0003674(molecular_function);GO:0008150(biological_process);GO:0005575(cellular_component);GO:0003723(RNA binding);GO:0003723(RNA binding)","NA","NA","NA","KH and NYN domain containing [Source:HGNC Symbol;Acc:HGNC:20166]",{"v":6.22300243006862,"d":"6.22"},{"v":3.47956544366812,"d":"3.48"},{"v":1.7884424163922,"d":"1.79"},{"v":0.838703667719323,"d":"0.84"},{"v":0.189477579790464,"d":"0.19"},{"v":0.978302124958596,"d":"0.98"},"up","no"]
["ENSG00000138030","KHK","ENST00000260599;ENST00000469936;ENST00000464371","GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0005515(protein binding);GO:0005975(carbohydrate metabolic process);GO:0004454(ketohexokinase activity);GO:0006000(fructose metabolic process);GO:0009744(response to sucrose);GO:0009749(response to glucose);GO:0009750(response to fructose);GO:0010043(response to zinc ion);GO:0032868(response to insulin);GO:0046835(carbohydrate phosphorylation);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0061624(fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate);GO:0061624(fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate)","00051(Fructose and mannose metabolism);00051(Fructose and mannose metabolism)","K00846","EC:2.7.1.3","ketohexokinase [Source:HGNC Symbol;Acc:HGNC:6315]",{"v":0.546565785620915,"d":"0.55"},{"v":0.293865518300654,"d":"0.29"},{"v":1.8599180631384,"d":"1.86"},{"v":0.895239066221658,"d":"0.90"},{"v":0.189720519010354,"d":"0.19"},{"v":0.978302124958596,"d":"0.98"},"up","no"]
["MSTRG.2045","PTPRE","ENST00000306042;MSTRG.2045.9;ENST00000479896;ENST00000463727;MSTRG.2045.8;ENST00000492479;ENST00000471218;MSTRG.2045.6;MSTRG.2045.7;ENST00000467366;ENST00000487428;ENST00000254667","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016787(hydrolase activity);GO:0004725(protein tyrosine phosphatase activity);GO:0016791(phosphatase activity);GO:0006470(protein dephosphorylation);GO:0016311(dephosphorylation);GO:0035335(peptidyl-tyrosine dephosphorylation);GO:0005886(plasma membrane);GO:0004721(phosphoprotein phosphatase activity);GO:0005515(protein binding);GO:0046627(negative regulation of insulin receptor signaling pathway);GO:0005001(transmembrane receptor protein tyrosine phosphatase activity);GO:0005001(transmembrane receptor protein tyrosine phosphatase activity)","NA","NA","NA","protein tyrosine phosphatase, receptor type E [Source:HGNC Symbol;Acc:HGNC:9669]",{"v":6.08481165077812,"d":"6.08"},{"v":11.2608162047132,"d":"11.26"},{"v":0.540352629876983,"d":"0.54"},{"v":-0.888026888834098,"d":"-0.89"},{"v":0.191250997215788,"d":"0.19"},{"v":0.979374261798653,"d":"0.98"},"down","no"]
["ENSG00000100095","SEZ6L","ENST00000529632;ENST00000483291;ENST00000402979;ENST00000360929;ENST00000494013;ENST00000248933;ENST00000404234","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0008344(adult locomotory behavior);GO:0021680(cerebellar Purkinje cell layer development);GO:0060074(synapse maturation);GO:0090036(regulation of protein kinase C signaling);GO:0043025(neuronal cell body);GO:0043025(neuronal cell body)","NA","NA","NA","seizure related 6 homolog like [Source:HGNC Symbol;Acc:HGNC:10763]",{"v":0.125328682333193,"d":"0.13"},{"v":0.238532482584977,"d":"0.24"},{"v":0.525415578519981,"d":"0.53"},{"v":-0.928469118016262,"d":"-0.93"},{"v":0.193856998623041,"d":"0.19"},{"v":0.98494282494992,"d":"0.98"},"down","no"]
["MSTRG.6624","SSH2","MSTRG.6624.1;MSTRG.6624.2;ENST00000577991;ENST00000590153;ENST00000582084;ENST00000579040;ENST00000540801;ENST00000579954;ENST00000269033;ENST00000324677;ENST00000578411;ENST00000577483;ENST00000394848","GO:0005737(cytoplasm);GO:0016787(hydrolase activity);GO:0003779(actin binding);GO:0004725(protein tyrosine phosphatase activity);GO:0008138(protein tyrosine/serine/threonine phosphatase activity);GO:0016791(phosphatase activity);GO:0006470(protein dephosphorylation);GO:0016311(dephosphorylation);GO:0035335(peptidyl-tyrosine dephosphorylation);GO:0004721(phosphoprotein phosphatase activity);GO:0005856(cytoskeleton);GO:0005615(extracellular space);GO:0030036(actin cytoskeleton organization);GO:0050770(regulation of axonogenesis);GO:0010591(regulation of lamellipodium assembly);GO:0008064(regulation of actin polymerization or depolymerization);GO:0030335(positive regulation of cell migration);GO:0030335(positive regulation of cell migration)","04810(Regulation of actin cytoskeleton);04360(Axon guidance);04360(Axon guidance)","K05766","EC:3.1.3.16;EC:3.1.3.48","slingshot protein phosphatase 2 [Source:HGNC Symbol;Acc:HGNC:30580]",{"v":7.98682666093676,"d":"7.99"},{"v":14.7007548589339,"d":"14.70"},{"v":0.543293642916781,"d":"0.54"},{"v":-0.880195928765466,"d":"-0.88"},{"v":0.194861873015987,"d":"0.19"},{"v":0.98494282494992,"d":"0.98"},"down","no"]
["ENSG00000162104","ADCY9","ENST00000294016;ENST00000571889;ENST00000572288;ENST00000574721;ENST00000575550;ENST00000571467;ENST00000576936","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0035556(intracellular signal transduction);GO:0016829(lyase activity);GO:0005886(plasma membrane);GO:0005887(integral component of plasma membrane);GO:0016849(phosphorus-oxygen lyase activity);GO:0009190(cyclic nucleotide biosynthetic process);GO:0004016(adenylate cyclase activity);GO:0006171(cAMP biosynthetic process);GO:0007193(adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway);GO:0007165(signal transduction);GO:0004383(guanylate cyclase activity);GO:0003091(renal water homeostasis);GO:0006182(cGMP biosynthetic process);GO:0007189(adenylate cyclase-activating G-protein coupled receptor signaling pathway);GO:0007190(activation of adenylate cyclase activity);GO:0034199(activation of protein kinase A activity);GO:0071377(cellular response to glucagon stimulus);GO:0008074(guanylate cyclase complex, soluble);GO:0071880(adenylate cyclase-activating adrenergic receptor signaling pathway);GO:0030424(axon);GO:0030425(dendrite);GO:0005622(intracellular);GO:0005622(intracellular)","00230(Purine metabolism);04015(Rap1 signaling pathway);04371(Apelin signaling pathway);04020(Calcium signaling pathway);04072(Phospholipase D signaling pathway);04024(cAMP signaling pathway);04022(cGMP - PKG signaling pathway);04114(Oocyte meiosis);04540(Gap junction);04611(Platelet activation);04062(Chemokine signaling pathway);04911(Insulin secretion);04923(Regulation of lipolysis in adipocyte);04912(GnRH signaling pathway);04913(Ovarian Steroidogenesis);04915(Estrogen signaling pathway);04914(Progesterone-mediated oocyte maturation);04921(Oxytocin signaling pathway);04926(Relaxin signaling pathway);04918(Thyroid hormone synthesis);04916(Melanogenesis);04925(Aldosterone synthesis and secretion);04927(Cortisol synthesis and secretion);04261(Adrenergic signaling in cardiomyocytes);04270(Vascular smooth muscle contraction);04970(Salivary secretion);04971(Gastric acid secretion);04972(Pancreatic secretion);04976(Bile secretion);04962(Vasopressin-regulated water reabsorption);04961(Endocrine and other factor-regulated calcium reabsorption);04724(Glutamatergic synapse);04727(GABAergic synapse);04725(Cholinergic synapse);04723(Retrograde endocannabinoid signaling);04750(Inflammatory mediator regulation of TRP channels);04211(Longevity regulating pathway - mammal);04213(Longevity regulating pathway - multiple species);04713(Circadian entrainment);05200(Pathways in cancer);05032(Morphine addiction);05414(Dilated cardiomyopathy (DCM));05110(Vibrio cholerae infection);05166(HTLV-I infection);01522(Endocrine resistance);01522(Endocrine resistance)","K08049","EC:4.6.1.1","adenylate cyclase 9 [Source:HGNC Symbol;Acc:HGNC:240]",{"v":1.9336301024329,"d":"1.93"},{"v":1.08886825371693,"d":"1.09"},{"v":1.7758164000395,"d":"1.78"},{"v":0.828482430536654,"d":"0.83"},{"v":0.19593900509038,"d":"0.20"},{"v":0.98494282494992,"d":"0.98"},"up","no"]
["MSTRG.1205","ZBTB37","ENST00000367701;ENST00000427304;ENST00000367702;ENST00000367704","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0003677(DNA binding)","NA","NA","NA","zinc finger and BTB domain containing 37 [Source:HGNC Symbol;Acc:HGNC:28365]",{"v":1.12851760419236,"d":"1.13"},{"v":0.63620982079737,"d":"0.64"},{"v":1.77381355537388,"d":"1.77"},{"v":0.826854376677685,"d":"0.83"},{"v":0.196766204366109,"d":"0.20"},{"v":0.98494282494992,"d":"0.98"},"up","no"]
["MSTRG.4093","ABHD13","ENST00000375898","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016787(hydrolase activity)","NA","NA","NA","abhydrolase domain containing 13 [Source:HGNC Symbol;Acc:HGNC:20293]",{"v":2.393177,"d":"2.39"},{"v":4.393469,"d":"4.39"},{"v":0.544712390140912,"d":"0.54"},{"v":-0.8764334114954,"d":"-0.88"},{"v":0.198816349300103,"d":"0.20"},{"v":0.988472838167664,"d":"0.99"},"down","no"]
["ENSG00000282508","LINC01002","ENST00000631858;ENST00000631401;ENST00000632102;ENST00000633808;ENST00000632075;ENST00000632351;ENST00000631764;ENST00000632086;ENST00000632747;ENST00000633671;ENST00000633592;ENST00000634022;ENST00000632624;ENST00000631988;ENST00000633151;ENST00000632790;ENST00000631772;ENST00000632203;ENST00000633295;ENST00000631484;ENST00000632405;ENST00000633951;ENST00000631644;ENST00000631797;ENST00000631832;ENST00000633522;ENST00000633344;ENST00000631864;ENST00000633109;ENST00000633179;ENST00000633363","NA","NA","NA","NA","long intergenic non-protein coding RNA 1002 [Source:HGNC Symbol;Acc:HGNC:38538]",{"v":1.06650449259498,"d":"1.07"},{"v":1.97091709349646,"d":"1.97"},{"v":0.541120931019464,"d":"0.54"},{"v":-0.885977047812148,"d":"-0.89"},{"v":0.200379619327459,"d":"0.20"},{"v":0.989470731631903,"d":"0.99"},"down","no"]
["MSTRG.9714","AAR2","ENST00000320849;ENST00000373932","GO:0000244(spliceosomal tri-snRNP complex assembly);GO:0000244(spliceosomal tri-snRNP complex assembly)","NA","NA","NA","AAR2 splicing factor homolog [Source:HGNC Symbol;Acc:HGNC:15886]",{"v":4.43387391486617,"d":"4.43"},{"v":2.50484505707836,"d":"2.50"},{"v":1.77011903484275,"d":"1.77"},{"v":0.823846380196981,"d":"0.82"},{"v":0.201343931536401,"d":"0.20"},{"v":0.989470731631903,"d":"0.99"},"up","no"]
["MSTRG.1608","PIP4K2A","ENST00000376573;ENST00000545335;ENST00000432610;ENST00000422321;ENST00000323883;ENST00000474335;ENST00000604912","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0005886(plasma membrane);GO:0016307(phosphatidylinositol phosphate kinase activity);GO:0046488(phosphatidylinositol metabolic process);GO:0046854(phosphatidylinositol phosphorylation);GO:0005575(cellular_component);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0005776(autophagosome);GO:0006661(phosphatidylinositol biosynthetic process);GO:0014066(regulation of phosphatidylinositol 3-kinase signaling);GO:0016308(1-phosphatidylinositol-4-phosphate 5-kinase activity);GO:0052811(1-phosphatidylinositol-3-phosphate 4-kinase activity);GO:0010506(regulation of autophagy);GO:0006644(phospholipid metabolic process);GO:0016309(1-phosphatidylinositol-5-phosphate 4-kinase activity);GO:0035855(megakaryocyte development);GO:2000786(positive regulation of autophagosome assembly);GO:2000786(positive regulation of autophagosome assembly)","00562(Inositol phosphate metabolism);04070(Phosphatidylinositol signaling system);04810(Regulation of actin cytoskeleton);04810(Regulation of actin cytoskeleton)","K00920","EC:2.7.1.149","phosphatidylinositol-5-phosphate 4-kinase type 2 alpha [Source:HGNC Symbol;Acc:HGNC:8997]",{"v":44.8866238854305,"d":"44.89"},{"v":25.574874103532,"d":"25.57"},{"v":1.75510634788351,"d":"1.76"},{"v":0.811558450994622,"d":"0.81"},{"v":0.202962732790049,"d":"0.20"},{"v":0.991810403150802,"d":"0.99"},"up","no"]
["ENSG00000094804","CDC6","ENST00000209728;ENST00000577249","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005794(Golgi apparatus);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0051301(cell division);GO:0005515(protein binding);GO:0006270(DNA replication initiation);GO:0045737(positive regulation of cyclin-dependent protein serine/threonine kinase activity);GO:0048146(positive regulation of fibroblast proliferation);GO:1904117(cellular response to vasopressin);GO:1904385(cellular response to angiotensin);GO:0007049(cell cycle);GO:0006260(DNA replication);GO:0000082(G1/S transition of mitotic cell cycle);GO:0008285(negative regulation of cell proliferation);GO:0000278(mitotic cell cycle);GO:0019900(kinase binding);GO:0000079(regulation of cyclin-dependent protein serine/threonine kinase activity);GO:0000076(DNA replication checkpoint);GO:0000083(regulation of transcription involved in G1/S transition of mitotic cell cycle);GO:0000922(spindle pole);GO:0008156(negative regulation of DNA replication);GO:0030071(regulation of mitotic metaphase/anaphase transition);GO:0051233(spindle midzone);GO:0007089(traversing start control point of mitotic cell cycle);GO:0032467(positive regulation of cytokinesis);GO:0051984(positive regulation of chromosome segregation);GO:0051984(positive regulation of chromosome segregation)","04110(Cell cycle);04110(Cell cycle)","K02213","NA","cell division cycle 6 [Source:HGNC Symbol;Acc:HGNC:1744]",{"v":0.24921248828125,"d":"0.25"},{"v":0.135148787109375,"d":"0.14"},{"v":1.84398612530325,"d":"1.84"},{"v":0.882827800544093,"d":"0.88"},{"v":0.203417255974589,"d":"0.20"},{"v":0.991810403150802,"d":"0.99"},"up","no"]
["MSTRG.3370","DIP2B","ENST00000301180;ENST00000546719;ENST00000546732;ENST00000549620","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0003824(catalytic activity);GO:0008152(metabolic process);GO:0003674(molecular_function);GO:0008150(biological_process);GO:0070062(extracellular exosome);GO:0070062(extracellular exosome)","NA","NA","NA","disco interacting protein 2 homolog B [Source:HGNC Symbol;Acc:HGNC:29284]",{"v":3.91830854608628,"d":"3.92"},{"v":7.11575422246888,"d":"7.12"},{"v":0.550652597543874,"d":"0.55"},{"v":-0.860785674217392,"d":"-0.86"},{"v":0.205080508431325,"d":"0.21"},{"v":0.992668837500125,"d":"0.99"},"down","no"]
["ENSG00000117020","AKT3","ENST00000366539;ENST00000366540;ENST00000263826;ENST00000552631;ENST00000463991;ENST00000491219;ENST00000492957","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0005515(protein binding);GO:0007165(signal transduction);GO:0005622(intracellular);GO:0035556(intracellular signal transduction);GO:0018105(peptidyl-serine phosphorylation);GO:0000002(mitochondrial genome maintenance);GO:0032008(positive regulation of TOR signaling);GO:0045793(positive regulation of cell size);GO:0048854(brain morphogenesis);GO:0048873(homeostasis of number of cells within a tissue);GO:0048873(homeostasis of number of cells within a tissue)","04014(Ras signaling pathway);04015(Rap1 signaling pathway);04010(MAPK signaling pathway);04012(ErbB signaling pathway);04370(VEGF signaling pathway);04371(Apelin signaling pathway);04630(Jak-STAT signaling pathway);04668(TNF signaling pathway);04066(HIF-1 signaling pathway);04068(FoxO signaling pathway);04072(Phospholipase D signaling pathway);04071(Sphingolipid signaling pathway);04024(cAMP signaling pathway);04022(cGMP - PKG signaling pathway);04151(PI3K-Akt signaling pathway);04152(AMPK signaling pathway);04150(mTOR signaling pathway);04140(Autophagy - animal);04210(Apoptosis);04218(Cellular senescence);04510(Focal adhesion);04550(Signaling pathways regulating pluripotency of stem cells);04611(Platelet activation);04620(Toll-like receptor signaling pathway);04660(T cell receptor signaling pathway);04662(B cell receptor signaling pathway);04664(Fc epsilon RI signaling pathway);04666(Fc gamma R-mediated phagocytosis);04062(Chemokine signaling pathway);04910(Insulin signaling pathway);04922(Glucagon signaling pathway);04923(Regulation of lipolysis in adipocyte);04920(Adipocytokine signaling pathway);04915(Estrogen signaling pathway);04914(Progesterone-mediated oocyte maturation);04917(Prolactin signaling pathway);04926(Relaxin signaling pathway);04919(Thyroid hormone signaling pathway);04261(Adrenergic signaling in cardiomyocytes);04973(Carbohydrate digestion and absorption);04725(Cholinergic synapse);04728(Dopaminergic synapse);04722(Neurotrophin signaling pathway);04380(Osteoclast differentiation);04211(Longevity regulating pathway - mammal);04213(Longevity regulating pathway - multiple species);05200(Pathways in cancer);05230(Central carbon metabolism in cancer);05231(Choline metabolism in cancer);05205(Proteoglycans in cancer);05210(Colorectal cancer);05212(Pancreatic cancer);05225(Hepatocellular carcinoma);05226(Gastric cancer);05214(Glioma);05221(Acute myeloid leukemia);05220(Chronic myeloid leukemia);05218(Melanoma);05211(Renal cell carcinoma);05215(Prostate cancer);05213(Endometrial cancer);05224(Breast cancer);05222(Small cell lung cancer);05223(Non-small cell lung cancer);05418(Fluid shear stress and atherosclerosis);04932(Non-alcoholic fatty liver disease (NAFLD));04931(Insulin resistance);04933(AGE-RAGE signaling pathway in diabetic complications);05152(Tuberculosis);05166(HTLV-I infection);05162(Measles);05164(Influenza A);05161(Hepatitis B);05160(Hepatitis C);05167(Kaposi's sarcoma-associated herpesvirus infection);05169(Epstein-Barr virus infection);05165(Human papillomavirus infection);05145(Toxoplasmosis);05142(Chagas disease (American trypanosomiasis));01521(EGFR tyrosine kinase inhibitor resistance);01524(Platinum drug resistance);01522(Endocrine resistance);01522(Endocrine resistance)","K04456","EC:2.7.11.1","AKT serine/threonine kinase 3 [Source:HGNC Symbol;Acc:HGNC:393]",{"v":0.823549359472296,"d":"0.82"},{"v":1.50111978437995,"d":"1.50"},{"v":0.548623346412338,"d":"0.55"},{"v":-0.866112078175767,"d":"-0.87"},{"v":0.206504359655033,"d":"0.21"},{"v":0.993966650102607,"d":"0.99"},"down","no"]
["ENSG00000280173","AC104447.1","ENST00000624214","NA","NA","NA","NA",null,{"v":0.621794,"d":"0.62"},{"v":0.335305,"d":"0.34"},{"v":1.85441314623999,"d":"1.85"},{"v":0.890962698995856,"d":"0.89"},{"v":0.20730129461097,"d":"0.21"},{"v":0.993966650102607,"d":"0.99"},"up","no"]
["MSTRG.8084","TYROBP","MSTRG.8084.2;ENST00000587837;ENST00000424586;ENST00000262629;ENST00000589517;ENST00000586946;ENST00000585901;ENST00000544690;ENST00000588439;MSTRG.8084.1;MSTRG.8084.3;MSTRG.8084.4;ENST00000585626;MSTRG.8084.7","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005515(protein binding);GO:0050776(regulation of immune response);GO:0005886(plasma membrane);GO:0042802(identical protein binding);GO:0045087(innate immune response);GO:0005887(integral component of plasma membrane);GO:0005102(receptor binding);GO:0043312(neutrophil degranulation);GO:0007165(signal transduction);GO:0009986(cell surface);GO:0030667(secretory granule membrane);GO:0035556(intracellular signal transduction);GO:0005057(signal transducer activity, downstream of receptor);GO:0006968(cellular defense response);GO:0002281(macrophage activation involved in immune response);GO:0002283(neutrophil activation involved in immune response);GO:0007229(integrin-mediated signaling pathway);GO:2001204(regulation of osteoclast development);GO:2001204(regulation of osteoclast development)","04650(Natural killer cell mediated cytotoxicity);04380(Osteoclast differentiation);04380(Osteoclast differentiation)","K07992","NA","TYRO protein tyrosine kinase binding protein [Source:HGNC Symbol;Acc:HGNC:12449]",{"v":34.3466581534501,"d":"34.35"},{"v":62.1775389062822,"d":"62.18"},{"v":0.552396552800513,"d":"0.55"},{"v":-0.856223778320221,"d":"-0.86"},{"v":0.207869775012989,"d":"0.21"},{"v":0.994504501671201,"d":"0.99"},"down","no"]
["ENSG00000172985","SH3RF3","ENST00000309415","GO:0046872(metal ion binding);GO:0005515(protein binding)","NA","NA","NA","SH3 domain containing ring finger 3 [Source:HGNC Symbol;Acc:HGNC:24699]",{"v":0.719716,"d":"0.72"},{"v":0.40752,"d":"0.41"},{"v":1.76608755398508,"d":"1.77"},{"v":0.820556866524899,"d":"0.82"},{"v":0.209417416221839,"d":"0.21"},{"v":0.994848028617088,"d":"0.99"},"up","no"]
["MSTRG.14642","TONSL","ENST00000497613;ENST00000409379","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005654(nucleoplasm);GO:0005515(protein binding);GO:0006281(DNA repair);GO:0006974(cellular response to DNA damage stimulus);GO:0016604(nuclear body);GO:1903507(negative regulation of nucleic acid-templated transcription);GO:0031297(replication fork processing);GO:0042393(histone binding);GO:0042994(cytoplasmic sequestering of transcription factor);GO:0003714(transcription corepressor activity);GO:0000724(double-strand break repair via homologous recombination);GO:0005662(DNA replication factor A complex);GO:0043596(nuclear replication fork);GO:0042555(MCM complex);GO:0035101(FACT complex);GO:0035101(FACT complex)","NA","NA","NA","tonsoku like, DNA repair protein [Source:HGNC Symbol;Acc:HGNC:7801]",{"v":0.32105662016594,"d":"0.32"},{"v":0.179646486007594,"d":"0.18"},{"v":1.78715780809856,"d":"1.79"},{"v":0.83766703164252,"d":"0.84"},{"v":0.210439216962733,"d":"0.21"},{"v":0.994848028617088,"d":"0.99"},"up","no"]
["ENSG00000110987","BCL7A","ENST00000538010;ENST00000432926;ENST00000261822","GO:0005515(protein binding);GO:0003674(molecular_function);GO:0005575(cellular_component);GO:0045892(negative regulation of transcription, DNA-templated);GO:0045892(negative regulation of transcription, DNA-templated)","NA","NA","NA","BCL tumor suppressor 7A [Source:HGNC Symbol;Acc:HGNC:1004]",{"v":0.337394782939832,"d":"0.34"},{"v":0.620572156587967,"d":"0.62"},{"v":0.543683404674321,"d":"0.54"},{"v":-0.879161302726069,"d":"-0.88"},{"v":0.211329071813219,"d":"0.21"},{"v":0.995238436751966,"d":"1.00"},"down","no"]
["ENSG00000166851","PLK1","ENST00000562272;ENST00000564794;ENST00000300093;ENST00000562407;ENST00000564947","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0016567(protein ubiquitination);GO:0051301(cell division);GO:0005694(chromosome);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0007049(cell cycle);GO:0008017(microtubule binding);GO:0005813(centrosome);GO:0005815(microtubule organizing center);GO:0005819(spindle);GO:0030496(midbody);GO:0000775(chromosome, centromeric region);GO:0000776(kinetochore);GO:0000777(condensed chromosome kinetochore);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0019901(protein kinase binding);GO:0031648(protein destabilization);GO:0031145(anaphase-promoting complex-dependent catabolic process);GO:0051437(positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition);GO:0051233(spindle midzone);GO:0000086(G2/M transition of mitotic cell cycle);GO:0010389(regulation of G2/M transition of mitotic cell cycle);GO:0097711(ciliary basal body docking);GO:0007098(centrosome cycle);GO:0007346(regulation of mitotic cell cycle);GO:0007062(sister chromatid cohesion);GO:0043066(negative regulation of apoptotic process);GO:0008283(cell proliferation);GO:0042787(protein ubiquitination involved in ubiquitin-dependent protein catabolic process);GO:0051439(regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle);GO:1904668(positive regulation of ubiquitin protein ligase activity);GO:0000278(mitotic cell cycle);GO:0000281(mitotic cytokinesis);GO:0000910(cytokinesis);GO:0031572(G2 DNA damage checkpoint);GO:0000942(condensed nuclear chromosome outer kinetochore);GO:0005876(spindle microtubule);GO:0015630(microtubule cytoskeleton);GO:0010800(positive regulation of peptidyl-threonine phosphorylation);GO:0045862(positive regulation of proteolysis);GO:0007077(mitotic nuclear envelope disassembly);GO:0000287(magnesium ion binding);GO:0000070(mitotic sister chromatid segregation);GO:0001578(microtubule bundle formation);GO:0007094(mitotic spindle assembly checkpoint);GO:0071168(protein localization to chromatin);GO:0032436(positive regulation of proteasomal ubiquitin-dependent protein catabolic process);GO:0051726(regulation of cell cycle);GO:0018105(peptidyl-serine phosphorylation);GO:1902749(regulation of cell cycle G2/M phase transition);GO:0045184(establishment of protein localization);GO:0000922(spindle pole);GO:0043393(regulation of protein binding);GO:0045736(negative regulation of cyclin-dependent protein serine/threonine kinase activity);GO:0051443(positive regulation of ubiquitin-protein transferase activity);GO:0010997(anaphase-promoting complex binding);GO:0016321(female meiosis chromosome segregation);GO:0030071(regulation of mitotic metaphase/anaphase transition);GO:0045143(homologous chromosome segregation);GO:0051081(nuclear envelope disassembly);GO:0070194(synaptonemal complex disassembly);GO:0090435(protein localization to nuclear envelope);GO:1900182(positive regulation of protein localization to nucleus);GO:1901673(regulation of mitotic spindle assembly);GO:0000780(condensed nuclear chromosome, centromeric region);GO:0000785(chromatin);GO:0000795(synaptonemal complex);GO:0000795(synaptonemal complex)","04068(FoxO signaling pathway);04110(Cell cycle);04114(Oocyte meiosis);04914(Progesterone-mediated oocyte maturation);04914(Progesterone-mediated oocyte maturation)","K06631","EC:2.7.11.21","polo like kinase 1 [Source:HGNC Symbol;Acc:HGNC:9077]",{"v":0.440933143697479,"d":"0.44"},{"v":0.248979684663866,"d":"0.25"},{"v":1.77096032671404,"d":"1.77"},{"v":0.824531893007945,"d":"0.82"},{"v":0.213070834459313,"d":"0.21"},{"v":0.995653468591017,"d":"1.00"},"up","no"]
["MSTRG.1742","RUFY2","ENST00000388768;ENST00000491118;ENST00000265865;ENST00000473398;ENST00000399200;ENST00000466187;ENST00000466493;ENST00000342616;ENST00000602465","GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0046872(metal ion binding)","NA","NA","NA","RUN and FYVE domain containing 2 [Source:HGNC Symbol;Acc:HGNC:19761]",{"v":0.502020231534964,"d":"0.50"},{"v":0.285490863340297,"d":"0.29"},{"v":1.7584458769056,"d":"1.76"},{"v":0.814300931027172,"d":"0.81"},{"v":0.215005043802996,"d":"0.22"},{"v":0.997279184244309,"d":"1.00"},"up","no"]
["ENSG00000168280","KIF5C","ENST00000435030;ENST00000464066;ENST00000482151;ENST00000460377","GO:0006810(transport);GO:0051028(mRNA transport);GO:0005737(cytoplasm);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0003777(microtubule motor activity);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0008017(microtubule binding);GO:0005874(microtubule);GO:0007018(microtubule-based movement);GO:0030705(cytoskeleton-dependent intracellular transport);GO:0007411(axon guidance);GO:0008574(ATP-dependent microtubule motor activity, plus-end-directed);GO:0005871(kinesin complex);GO:0008104(protein localization);GO:0006996(organelle organization);GO:0008045(motor neuron axon guidance);GO:0035253(ciliary rootlet);GO:0043005(neuron projection);GO:0043005(neuron projection)","04144(Endocytosis);04728(Dopaminergic synapse);04728(Dopaminergic synapse)","K10396","NA","kinesin family member 5C [Source:HGNC Symbol;Acc:HGNC:6325]",{"v":0.478930413998915,"d":"0.48"},{"v":0.273325610743353,"d":"0.27"},{"v":1.75223394798748,"d":"1.75"},{"v":0.80919540796923,"d":"0.81"},{"v":0.215858818184682,"d":"0.22"},{"v":0.997279184244309,"d":"1.00"},"up","no"]
["ENSG00000204946","ZNF783","ENST00000434415;ENST00000476295;ENST00000378052;ENST00000481519","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0005622(intracellular);GO:0005515(protein binding);GO:0042802(identical protein binding);GO:0042802(identical protein binding)","NA","NA","NA","zinc finger family member 783 [Source:HGNC Symbol;Acc:HGNC:27222]",{"v":1.91325777252453,"d":"1.91"},{"v":1.10186520011894,"d":"1.10"},{"v":1.73638097683637,"d":"1.74"},{"v":0.796083522143558,"d":"0.80"},{"v":0.217095554885649,"d":"0.22"},{"v":0.997430244919108,"d":"1.00"},"up","no"]
["ENSG00000274588","DGKK","ENST00000611977","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0035556(intracellular signal transduction);GO:0008152(metabolic process);GO:0003951(NAD+ kinase activity);GO:0004143(diacylglycerol kinase activity);GO:0007205(protein kinase C-activating G-protein coupled receptor signaling pathway);GO:0005886(plasma membrane);GO:0030168(platelet activation);GO:0006979(response to oxidative stress);GO:0046339(diacylglycerol metabolic process)","00561(Glycerolipid metabolism);00564(Glycerophospholipid metabolism);04070(Phosphatidylinositol signaling system);04072(Phospholipase D signaling pathway);05231(Choline metabolism in cancer)","K00901","EC:2.7.1.107","diacylglycerol kinase kappa [Source:HGNC Symbol;Acc:HGNC:32395]",{"v":0.377292,"d":"0.38"},{"v":0.212792,"d":"0.21"},{"v":1.77305537802173,"d":"1.77"},{"v":0.826237596783499,"d":"0.83"},{"v":0.217998042412804,"d":"0.22"},{"v":0.998651962005035,"d":"1.00"},"up","no"]
["ENSG00000136636","KCTD3","ENST00000259154;ENST00000448333;ENST00000465650;ENST00000495537","GO:0051260(protein homooligomerization);GO:0051260(protein homooligomerization)","NA","NA","NA","potassium channel tetramerization domain containing 3 [Source:HGNC Symbol;Acc:HGNC:21305]",{"v":0.193127150131873,"d":"0.19"},{"v":0.354937429904646,"d":"0.35"},{"v":0.544116043731304,"d":"0.54"},{"v":-0.878013726753625,"d":"-0.88"},{"v":0.219695489553844,"d":"0.22"},{"v":0.999487335929253,"d":"1.00"},"down","no"]
["MSTRG.2626","C11orf24","ENST00000304271;ENST00000529339;ENST00000532969;ENST00000529590;ENST00000527280;ENST00000531745;ENST00000530166;ENST00000533310;ENST00000532534","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005794(Golgi apparatus);GO:0005886(plasma membrane);GO:0005886(plasma membrane)","NA","NA","NA","chromosome 11 open reading frame 24 [Source:HGNC Symbol;Acc:HGNC:1174]",{"v":4.09802281826189,"d":"4.10"},{"v":2.37294027246036,"d":"2.37"},{"v":1.72698102258296,"d":"1.73"},{"v":0.78825222949343,"d":"0.79"},{"v":0.220230370048895,"d":"0.22"},{"v":0.999790359415809,"d":"1.00"},"up","no"]
["MSTRG.15423","ZBTB33","ENST00000326624;ENST00000557385","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0005730(nucleolus);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0016055(Wnt signaling pathway);GO:0043565(sequence-specific DNA binding);GO:0045892(negative regulation of transcription, DNA-templated);GO:0035556(intracellular signal transduction);GO:0008327(methyl-CpG binding);GO:0008327(methyl-CpG binding)","NA","NA","NA","zinc finger and BTB domain containing 33 [Source:HGNC Symbol;Acc:HGNC:16682]",{"v":3.3353363715415,"d":"3.34"},{"v":5.93573799435347,"d":"5.94"},{"v":0.561907613630239,"d":"0.56"},{"v":-0.831595146494532,"d":"-0.83"},{"v":0.222864034118376,"d":"0.22"},1,"down","no"]
["MSTRG.13939","ING3","ENST00000315870;ENST00000427726;ENST00000431467;ENST00000339121;ENST00000445699","GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0016569(covalent chromatin modification);GO:0004402(histone acetyltransferase activity);GO:0005654(nucleoplasm);GO:0040008(regulation of growth);GO:0043065(positive regulation of apoptotic process);GO:0043967(histone H4 acetylation);GO:0035064(methylated histone binding);GO:0043968(histone H2A acetylation);GO:0035267(NuA4 histone acetyltransferase complex);GO:0000812(Swr1 complex);GO:0032777(Piccolo NuA4 histone acetyltransferase complex);GO:0005515(protein binding);GO:0005515(protein binding)","NA","NA","NA","inhibitor of growth family member 3 [Source:HGNC Symbol;Acc:HGNC:14587]",{"v":1.37372279670119,"d":"1.37"},{"v":2.44536538454162,"d":"2.45"},{"v":0.561765863451401,"d":"0.56"},{"v":-0.831959135296103,"d":"-0.83"},{"v":0.22519136892508,"d":"0.23"},1,"down","no"]
["ENSG00000260942","CAPN10-AS1","ENST00000567819","NA","NA","NA","NA","CAPN10 antisense RNA 1 (head to head) [Source:HGNC Symbol;Acc:HGNC:48839]",{"v":0.408346,"d":"0.41"},{"v":0.230895,"d":"0.23"},{"v":1.76853548149592,"d":"1.77"},{"v":0.822555163604683,"d":"0.82"},{"v":0.225475759155014,"d":"0.23"},1,"up","no"]
["ENSG00000100228","RAB36","ENST00000263116;ENST00000420895","GO:0006810(transport);GO:0016020(membrane);GO:0015031(protein transport);GO:0005525(GTP binding);GO:0000166(nucleotide binding);GO:0003924(GTPase activity);GO:0005794(Golgi apparatus);GO:0000139(Golgi membrane);GO:0000139(Golgi membrane)","NA","NA","NA","RAB36, member RAS oncogene family [Source:HGNC Symbol;Acc:HGNC:9775]",{"v":0.279452388604821,"d":"0.28"},{"v":0.509953382517653,"d":"0.51"},{"v":0.547995950581124,"d":"0.55"},{"v":-0.867762862464544,"d":"-0.87"},{"v":0.227813999605042,"d":"0.23"},1,"down","no"]
["ENSG00000135801","TAF5L","ENST00000258281;ENST00000366675;ENST00000366674;ENST00000366676;ENST00000477957","GO:0005634(nucleus);GO:0016607(nuclear speck);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0005515(protein binding);GO:0004402(histone acetyltransferase activity);GO:0000932(P-body);GO:0003713(transcription coactivator activity);GO:0006366(transcription from RNA polymerase II promoter);GO:0033276(transcription factor TFTC complex);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0043966(histone H3 acetylation);GO:0030914(STAGA complex);GO:0030914(STAGA complex)","03022(Basal transcription factors);05168(Herpes simplex infection);05168(Herpes simplex infection)","K03130","NA","TATA-box binding protein associated factor 5 like [Source:HGNC Symbol;Acc:HGNC:17304]",{"v":0.96484215782907,"d":"0.96"},{"v":1.71204756612601,"d":"1.71"},{"v":0.563560368835019,"d":"0.56"},{"v":-0.827357934083522,"d":"-0.83"},{"v":0.22840705447892,"d":"0.23"},1,"down","no"]
["MSTRG.8533","HS1BP3","ENST00000304031;ENST00000402541;ENST00000446825;ENST00000415264;ENST00000458740;ENST00000406618;ENST00000445102","GO:0035091(phosphatidylinositol binding);GO:0005783(endoplasmic reticulum);GO:0042981(regulation of apoptotic process);GO:0005739(mitochondrion);GO:0005739(mitochondrion)","NA","NA","NA","HCLS1 binding protein 3 [Source:HGNC Symbol;Acc:HGNC:24979]",{"v":1.95796962335799,"d":"1.96"},{"v":3.45178908543989,"d":"3.45"},{"v":0.567233273787489,"d":"0.57"},{"v":-0.817985931632529,"d":"-0.82"},{"v":0.230405090832147,"d":"0.23"},1,"down","no"]
["ENSG00000160145","KALRN","ENST00000498499;ENST00000393496;ENST00000291478;ENST00000360013","GO:0005089(Rho guanyl-nucleotide exchange factor activity);GO:0035023(regulation of Rho protein signal transduction);GO:0043547(positive regulation of GTPase activity);GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0005856(cytoskeleton);GO:0005085(guanyl-nucleotide exchange factor activity);GO:0070062(extracellular exosome);GO:0005096(GTPase activator activity);GO:0051056(regulation of small GTPase mediated signal transduction);GO:0007165(signal transduction);GO:0016192(vesicle-mediated transport);GO:0048013(ephrin receptor signaling pathway);GO:0015629(actin cytoskeleton);GO:0043065(positive regulation of apoptotic process);GO:0035556(intracellular signal transduction);GO:0030676(Rac guanyl-nucleotide exchange factor activity);GO:0001662(behavioral fear response);GO:0007266(Rho protein signal transduction);GO:0007399(nervous system development);GO:0007528(neuromuscular junction development);GO:0007595(lactation);GO:0007613(memory);GO:0008344(adult locomotory behavior);GO:0009612(response to mechanical stimulus);GO:0014909(smooth muscle cell migration);GO:0035176(social behavior);GO:0042711(maternal behavior);GO:0046959(habituation);GO:0048148(behavioral response to cocaine);GO:0048168(regulation of neuronal synaptic plasticity);GO:0048659(smooth muscle cell proliferation);GO:0051966(regulation of synaptic transmission, glutamatergic);GO:0060125(negative regulation of growth hormone secretion);GO:0060137(maternal process involved in parturition);GO:0060999(positive regulation of dendritic spine development);GO:0061003(positive regulation of dendritic spine morphogenesis);GO:0061368(behavioral response to formalin induced pain);GO:1900273(positive regulation of long-term synaptic potentiation);GO:1903076(regulation of protein localization to plasma membrane);GO:0014069(postsynaptic density);GO:0014069(postsynaptic density)","NA","NA","NA","kalirin RhoGEF kinase [Source:HGNC Symbol;Acc:HGNC:4814]",{"v":0.0901098180481829,"d":"0.09"},{"v":0.0514042842792977,"d":"0.05"},{"v":1.75296318802114,"d":"1.75"},{"v":0.809795700023879,"d":"0.81"},{"v":0.231619625961504,"d":"0.23"},1,"up","no"]
["MSTRG.5936","OGFOD1","ENST00000566157;ENST00000569645;ENST00000569802;ENST00000565209;ENST00000563733;ENST00000565682","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0005829(cytosol);GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0005506(iron ion binding);GO:0016705(oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen);GO:0031418(L-ascorbic acid binding);GO:0051213(dioxygenase activity);GO:0016706(oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors);GO:0008283(cell proliferation);GO:0010494(cytoplasmic stress granule);GO:0034063(stress granule assembly);GO:0018126(protein hydroxylation);GO:0031543(peptidyl-proline dioxygenase activity);GO:0031544(peptidyl-proline 3-dioxygenase activity);GO:0006449(regulation of translational termination);GO:0019511(peptidyl-proline hydroxylation);GO:0019511(peptidyl-proline hydroxylation)","NA","NA","NA","2-oxoglutarate and iron dependent oxygenase domain containing 1 [Source:HGNC Symbol;Acc:HGNC:25585]",{"v":2.0802033287978,"d":"2.08"},{"v":1.22796534791595,"d":"1.23"},{"v":1.69402445462181,"d":"1.69"},{"v":0.760454701297598,"d":"0.76"},{"v":0.233374554906644,"d":"0.23"},1,"up","no"]
["ENSG00000119523","ALG2","ENST00000476832;ENST00000238477;ENST00000319033","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016740(transferase activity);GO:0016757(transferase activity, transferring glycosyl groups);GO:0048471(perinuclear region of cytoplasm);GO:0006486(protein glycosylation);GO:0097502(mannosylation);GO:0005515(protein binding);GO:0005789(endoplasmic reticulum membrane);GO:0048306(calcium-dependent protein binding);GO:0047485(protein N-terminus binding);GO:0046982(protein heterodimerization activity);GO:0051592(response to calcium ion);GO:0006488(dolichol-linked oligosaccharide biosynthetic process);GO:0000033(alpha-1,3-mannosyltransferase activity);GO:0004378(GDP-Man:Man1GlcNAc2-PP-Dol alpha-1,3-mannosyltransferase activity);GO:0102704(GDP-Man:Man2GlcNAc2-PP-dolichol alpha-1,6-mannosyltransferase activity);GO:0033577(protein glycosylation in endoplasmic reticulum);GO:0033577(protein glycosylation in endoplasmic reticulum)","00510(N-Glycan biosynthesis);00510(N-Glycan biosynthesis)","K03843","EC:2.4.1.132;EC:2.4.1.257","ALG2, alpha-1,3/1,6-mannosyltransferase [Source:HGNC Symbol;Acc:HGNC:23159]",{"v":2.43885397787462,"d":"2.44"},{"v":1.43212961112974,"d":"1.43"},{"v":1.70295618421766,"d":"1.70"},{"v":0.768041316035187,"d":"0.77"},{"v":0.234775032239805,"d":"0.23"},1,"up","no"]
["MSTRG.7602","MIDN","ENST00000586843;ENST00000591446;ENST00000590136;ENST00000300952;ENST00000591302","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005730(nucleolus);GO:0003674(molecular_function);GO:0008150(biological_process);GO:0019900(kinase binding);GO:0046676(negative regulation of insulin secretion);GO:0033132(negative regulation of glucokinase activity);GO:0033132(negative regulation of glucokinase activity)","NA","NA","NA","midnolin [Source:HGNC Symbol;Acc:HGNC:16298]",{"v":14.6803159394479,"d":"14.68"},{"v":25.6743096079697,"d":"25.67"},{"v":0.571790095375764,"d":"0.57"},{"v":-0.806442465257678,"d":"-0.81"},{"v":0.235856538259508,"d":"0.24"},1,"down","no"]
["MSTRG.4117","DCUN1D2","ENST00000460318;ENST00000332592;ENST00000465710;ENST00000491647;ENST00000375403;ENST00000478244;ENST00000482038;ENST00000465938;ENST00000439909","GO:0000151(ubiquitin ligase complex);GO:0031624(ubiquitin conjugating enzyme binding);GO:0097602(cullin family protein binding);GO:0032182(ubiquitin-like protein binding);GO:0045116(protein neddylation);GO:0051443(positive regulation of ubiquitin-protein transferase activity);GO:0051443(positive regulation of ubiquitin-protein transferase activity)","NA","NA","NA","defective in cullin neddylation 1 domain containing 2 [Source:HGNC Symbol;Acc:HGNC:20328]",{"v":0.245496481132075,"d":"0.25"},{"v":0.439449053152324,"d":"0.44"},{"v":0.558646057764925,"d":"0.56"},{"v":-0.839993572880954,"d":"-0.84"},{"v":0.237464224877087,"d":"0.24"},1,"down","no"]
["ENSG00000040199","PHLPP2","ENST00000393524;ENST00000567016;ENST00000568954;ENST00000574977;ENST00000538126","GO:0003824(catalytic activity);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0046872(metal ion binding);GO:0016787(hydrolase activity);GO:0004721(phosphoprotein phosphatase activity);GO:0005515(protein binding);GO:0005829(cytosol);GO:0007165(signal transduction);GO:0001917(photoreceptor inner segment);GO:0004722(protein serine/threonine phosphatase activity);GO:0006470(protein dephosphorylation);GO:0021766(hippocampus development);GO:0042622(photoreceptor outer segment membrane);GO:0042622(photoreceptor outer segment membrane)","04151(PI3K-Akt signaling pathway);04151(PI3K-Akt signaling pathway)","K16340","EC:3.1.3.16","PH domain and leucine rich repeat protein phosphatase 2 [Source:HGNC Symbol;Acc:HGNC:29149]",{"v":0.460154097974866,"d":"0.46"},{"v":0.271498390938926,"d":"0.27"},{"v":1.69486860081752,"d":"1.69"},{"v":0.761173428938512,"d":"0.76"},{"v":0.237547002472132,"d":"0.24"},1,"up","no"]
["MSTRG.14132","TMEM176A","ENST00000484928;ENST00000004103;ENST00000475007;ENST00000475536;ENST00000494349;ENST00000474166;ENST00000468689;ENST00000481305;ENST00000462826;ENST00000461345","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:2001199(negative regulation of dendritic cell differentiation);GO:2001199(negative regulation of dendritic cell differentiation)","NA","NA","NA","transmembrane protein 176A [Source:HGNC Symbol;Acc:HGNC:24930]",{"v":3.78348503219316,"d":"3.78"},{"v":6.60290792210405,"d":"6.60"},{"v":0.573002846144117,"d":"0.57"},{"v":-0.803385789922973,"d":"-0.80"},{"v":0.239877502194401,"d":"0.24"},1,"down","no"]
["MSTRG.7092","TACO1","ENST00000258975;ENST00000581120","GO:0005634(nucleus);GO:0005739(mitochondrion);GO:0005515(protein binding);GO:0006417(regulation of translation);GO:0006417(regulation of translation)","NA","NA","NA","translational activator of cytochrome c oxidase I [Source:HGNC Symbol;Acc:HGNC:24316]",{"v":1.06847254946004,"d":"1.07"},{"v":1.88300162030238,"d":"1.88"},{"v":0.567430499230511,"d":"0.57"},{"v":-0.81748439773638,"d":"-0.82"},{"v":0.240879759520223,"d":"0.24"},1,"down","no"]
["ENSG00000102910","LONP2","ENST00000535754;ENST00000285737;ENST00000565185;ENST00000570174;ENST00000416006;ENST00000566755;ENST00000564259;ENST00000566719","GO:0016020(membrane);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0016787(hydrolase activity);GO:0008233(peptidase activity);GO:0006508(proteolysis);GO:0004252(serine-type endopeptidase activity);GO:0008236(serine-type peptidase activity);GO:0005777(peroxisome);GO:0030163(protein catabolic process);GO:0005515(protein binding);GO:0005102(receptor binding);GO:0004176(ATP-dependent peptidase activity);GO:0006515(misfolded or incompletely synthesized protein catabolic process);GO:0019899(enzyme binding);GO:0002020(protease binding);GO:0006625(protein targeting to peroxisome);GO:0007031(peroxisome organization);GO:0005782(peroxisomal matrix);GO:0016485(protein processing);GO:0031998(regulation of fatty acid beta-oxidation);GO:0014070(response to organic cyclic compound);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005737(cytoplasm)","NA","NA","NA","lon peptidase 2, peroxisomal [Source:HGNC Symbol;Acc:HGNC:20598]",{"v":2.85463335492618,"d":"2.85"},{"v":1.70372330882796,"d":"1.70"},{"v":1.67552638397016,"d":"1.68"},{"v":0.744614404371814,"d":"0.74"},{"v":0.241798575759434,"d":"0.24"},1,"up","no"]
["MSTRG.9378","CD28","ENST00000324106;ENST00000458610;ENST00000374481","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005515(protein binding);GO:0006955(immune response);GO:0045727(positive regulation of translation);GO:0005886(plasma membrane);GO:0046854(phosphatidylinositol phosphorylation);GO:0005887(integral component of plasma membrane);GO:0005829(cytosol);GO:0010628(positive regulation of gene expression);GO:0042102(positive regulation of T cell proliferation);GO:0042802(identical protein binding);GO:0010629(negative regulation of gene expression);GO:0032753(positive regulation of interleukin-4 production);GO:0009986(cell surface);GO:0046934(phosphatidylinositol-4,5-bisphosphate 3-kinase activity);GO:0014066(regulation of phosphatidylinositol 3-kinase signaling);GO:0038111(interleukin-7-mediated signaling pathway);GO:0048015(phosphatidylinositol-mediated signaling);GO:0045840(positive regulation of mitotic nuclear division);GO:0031295(T cell costimulation);GO:0045070(positive regulation of viral genome replication);GO:0050690(regulation of defense response to virus by virus);GO:0005070(SH3/SH2 adaptor activity);GO:0015026(coreceptor activity);GO:0002020(protease binding);GO:0009897(external side of plasma membrane);GO:0006959(humoral immune response);GO:0007166(cell surface receptor signaling pathway);GO:0045086(positive regulation of interleukin-2 biosynthetic process);GO:0032733(positive regulation of interleukin-10 production);GO:0042089(cytokine biosynthetic process);GO:0045066(regulatory T cell differentiation);GO:0098636(protein complex involved in cell adhesion);GO:0019901(protein kinase binding);GO:0002863(positive regulation of inflammatory response to antigenic stimulus);GO:0014068(positive regulation of phosphatidylinositol 3-kinase signaling);GO:0045060(negative thymic T cell selection);GO:0045589(regulation of regulatory T cell differentiation);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0046641(positive regulation of alpha-beta T cell proliferation);GO:0048304(positive regulation of isotype switching to IgG isotypes);GO:0050852(T cell receptor signaling pathway);GO:0051897(positive regulation of protein kinase B signaling);GO:0097190(apoptotic signaling pathway);GO:0001772(immunological synapse);GO:0001772(immunological synapse)","04514(Cell adhesion molecules (CAMs));04660(T cell receptor signaling pathway);04672(Intestinal immune network for IgA production);05322(Systemic lupus erythematosus);05323(Rheumatoid arthritis);05320(Autoimmune thyroid disease);05330(Allograft rejection);05332(Graft-versus-host disease);05416(Viral myocarditis);04940(Type I diabetes mellitus);05162(Measles);05162(Measles)","K06470","NA","CD28 molecule [Source:HGNC Symbol;Acc:HGNC:1653]",{"v":7.20084793449335,"d":"7.20"},{"v":4.30445054534289,"d":"4.30"},{"v":1.67288434578117,"d":"1.67"},{"v":0.7423377086545,"d":"0.74"},{"v":0.243158344265797,"d":"0.24"},1,"up","no"]
["MSTRG.11632","CLOCK","ENST00000309964;ENST00000509151;ENST00000479384;ENST00000508049;ENST00000506747;ENST00000513033;ENST00000381322;ENST00000511124;ENST00000513440","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0043231(intracellular membrane-bounded organelle);GO:0005654(nucleoplasm);GO:0016740(transferase activity);GO:0046983(protein dimerization activity);GO:0006355(regulation of transcription, DNA-templated);GO:0006366(transcription from RNA polymerase II promoter);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0016746(transferase activity, transferring acyl groups);GO:0031490(chromatin DNA binding);GO:0005694(chromosome);GO:0006974(cellular response to DNA damage stimulus);GO:0048511(rhythmic process);GO:0005667(transcription factor complex);GO:0004402(histone acetyltransferase activity);GO:0016573(histone acetylation);GO:0045893(positive regulation of transcription, DNA-templated);GO:0007283(spermatogenesis);GO:0005515(protein binding);GO:0001047(core promoter binding);GO:0043565(sequence-specific DNA binding);GO:0007165(signal transduction);GO:0051092(positive regulation of NF-kappaB transcription factor activity);GO:0045892(negative regulation of transcription, DNA-templated);GO:0043161(proteasome-mediated ubiquitin-dependent protein catabolic process);GO:0000982(transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0070888(E-box binding);GO:0007623(circadian rhythm);GO:0032922(circadian regulation of gene expression);GO:0042634(regulation of hair cycle);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0050796(regulation of insulin secretion);GO:0051775(response to redox state);GO:2000074(regulation of type B pancreatic cell development);GO:2000323(negative regulation of glucocorticoid receptor signaling pathway);GO:0033391(chromatoid body);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0000077(DNA damage checkpoint);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:0001046(core promoter sequence-specific DNA binding);GO:0001190(transcriptional activator activity, RNA polymerase II transcription factor binding);GO:0009648(photoperiodism);GO:0050729(positive regulation of inflammatory response);GO:0071479(cellular response to ionizing radiation);GO:0071479(cellular response to ionizing radiation)","04728(Dopaminergic synapse);04710(Circadian rhythm);05168(Herpes simplex infection);05168(Herpes simplex infection)","K02223","EC:2.3.1.48","clock circadian regulator [Source:HGNC Symbol;Acc:HGNC:2082]",{"v":0.422825561554157,"d":"0.42"},{"v":0.742977394235674,"d":"0.74"},{"v":0.569096132445768,"d":"0.57"},{"v":-0.81325571988048,"d":"-0.81"},{"v":0.243286451281198,"d":"0.24"},1,"down","no"]
["ENSG00000134571","MYBPC3","ENST00000545968;ENST00000256993;ENST00000544791","GO:0046872(metal ion binding);GO:0007155(cell adhesion);GO:0003779(actin binding);GO:0005515(protein binding);GO:0042802(identical protein binding);GO:0005829(cytosol);GO:0051015(actin filament binding);GO:0051371(muscle alpha-actinin binding);GO:0097493(structural molecule activity conferring elasticity);GO:0006941(striated muscle contraction);GO:0007015(actin filament organization);GO:0045214(sarcomere organization);GO:0071688(striated muscle myosin thick filament assembly);GO:0030018(Z disc);GO:0031430(M band);GO:0032982(myosin filament);GO:0017022(myosin binding);GO:0060048(cardiac muscle contraction);GO:0055010(ventricular cardiac muscle tissue morphogenesis);GO:0003007(heart morphogenesis);GO:0008307(structural constituent of muscle);GO:0031432(titin binding);GO:0030049(muscle filament sliding);GO:0001671(ATPase activator activity);GO:0032781(positive regulation of ATPase activity);GO:0030017(sarcomere);GO:0006942(regulation of striated muscle contraction);GO:0031672(A band);GO:0032036(myosin heavy chain binding);GO:0097512(cardiac myofibril);GO:0005863(striated muscle myosin thick filament);GO:0032971(regulation of muscle filament sliding);GO:0014705(C zone);GO:0014705(C zone)","05410(Hypertrophic cardiomyopathy (HCM));05414(Dilated cardiomyopathy (DCM));05414(Dilated cardiomyopathy (DCM))","K12568","NA","myosin binding protein C, cardiac [Source:HGNC Symbol;Acc:HGNC:7551]",{"v":0.423581592757009,"d":"0.42"},{"v":0.748438390186916,"d":"0.75"},{"v":0.565953855802644,"d":"0.57"},{"v":-0.82124366500784,"d":"-0.82"},{"v":0.244661027017083,"d":"0.24"},1,"down","no"]
["ENSG00000132768","DPH2","ENST00000255108;ENST00000534786;ENST00000524776;ENST00000490861;ENST00000527567;ENST00000534655;ENST00000495421;ENST00000530988;ENST00000532140","GO:0016740(transferase activity);GO:0005515(protein binding);GO:0005829(cytosol);GO:0017183(peptidyl-diphthamide biosynthetic process from peptidyl-histidine);GO:0090560(2-(3-amino-3-carboxypropyl)histidine synthase activity);GO:0090560(2-(3-amino-3-carboxypropyl)histidine synthase activity)","NA","NA","NA","DPH2 homolog [Source:HGNC Symbol;Acc:HGNC:3004]",{"v":2.55700189795222,"d":"2.56"},{"v":1.52225618532423,"d":"1.52"},{"v":1.6797447910567,"d":"1.68"},{"v":0.748242056429329,"d":"0.75"},{"v":0.246391364852437,"d":"0.25"},1,"up","no"]
["MSTRG.12700","E2F3","MSTRG.12700.4;ENST00000613242;ENST00000535432;ENST00000346618","GO:0005634(nucleus);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0046983(protein dimerization activity);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0005515(protein binding);GO:0007049(cell cycle);GO:0005667(transcription factor complex);GO:0001047(core promoter binding);GO:0001228(transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding);GO:0043565(sequence-specific DNA binding);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0000977(RNA polymerase II regulatory region sequence-specific DNA binding);GO:0006367(transcription initiation from RNA polymerase II promoter);GO:0008284(positive regulation of cell proliferation);GO:0045893(positive regulation of transcription, DNA-templated);GO:0070345(negative regulation of fat cell proliferation);GO:0090575(RNA polymerase II transcription factor complex);GO:0090575(RNA polymerase II transcription factor complex)","04110(Cell cycle);04218(Cellular senescence);05200(Pathways in cancer);05206(MicroRNAs in cancer);05212(Pancreatic cancer);05225(Hepatocellular carcinoma);05226(Gastric cancer);05214(Glioma);05220(Chronic myeloid leukemia);05218(Melanoma);05219(Bladder cancer);05215(Prostate cancer);05224(Breast cancer);05222(Small cell lung cancer);05223(Non-small cell lung cancer);05166(HTLV-I infection);05161(Hepatitis B);05167(Kaposi's sarcoma-associated herpesvirus infection);01522(Endocrine resistance);01522(Endocrine resistance)","K06620","NA","E2F transcription factor 3 [Source:HGNC Symbol;Acc:HGNC:3115]",{"v":1.36791628931061,"d":"1.37"},{"v":2.36769887083656,"d":"2.37"},{"v":0.577740820912456,"d":"0.58"},{"v":-0.791505661404802,"d":"-0.79"},{"v":0.248211817488701,"d":"0.25"},1,"down","no"]
["ENSG00000139289","PHLDA1","ENST00000266671;ENST00000602540;ENST00000619060","GO:0005634(nucleus);GO:0005730(nucleolus);GO:0005737(cytoplasm);GO:0005515(protein binding);GO:0006915(apoptotic process);GO:0031410(cytoplasmic vesicle);GO:0005829(cytosol);GO:0000086(G2/M transition of mitotic cell cycle);GO:0045210(FasL biosynthetic process);GO:0045210(FasL biosynthetic process)","NA","NA","NA","pleckstrin homology like domain family A member 1 [Source:HGNC Symbol;Acc:HGNC:8933]",{"v":0.207566,"d":"0.21"},{"v":0.121434,"d":"0.12"},{"v":1.70929064347712,"d":"1.71"},{"v":0.773397730104678,"d":"0.77"},{"v":0.248701689590024,"d":"0.25"},1,"up","no"]
["MSTRG.9368","FAM117B","ENST00000392238","GO:0005515(protein binding)","NA","NA","NA","family with sequence similarity 117 member B [Source:HGNC Symbol;Acc:HGNC:14440]",{"v":4.25927098095556,"d":"4.26"},{"v":2.56709205446041,"d":"2.57"},{"v":1.65918124110701,"d":"1.66"},{"v":0.730471488080746,"d":"0.73"},{"v":0.251353243098079,"d":"0.25"},1,"up","no"]
["MSTRG.14842","BICD2","MSTRG.14842.1","NA","NA","NA","NA",null,{"v":4.366748,"d":"4.37"},{"v":7.814879,"d":"7.81"},{"v":0.558773590736338,"d":"0.56"},{"v":-0.839664258488726,"d":"-0.84"},{"v":0.252624884126981,"d":"0.25"},1,"down","no"]
["MSTRG.13807","TAF6","ENST00000453269;ENST00000472509;ENST00000452041;ENST00000460673;ENST00000487115;ENST00000437822;ENST00000520135;ENST00000493322;ENST00000523306;ENST00000344095;ENST00000421980;ENST00000440225;ENST00000451699;ENST00000497233;ENST00000487288","GO:0005634(nucleus);GO:0046982(protein heterodimerization activity);GO:0006352(DNA-templated transcription, initiation);GO:0005829(cytosol);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0005515(protein binding);GO:0051090(regulation of sequence-specific DNA binding transcription factor activity);GO:0006367(transcription initiation from RNA polymerase II promoter);GO:0005654(nucleoplasm);GO:0006366(transcription from RNA polymerase II promoter);GO:0045786(negative regulation of cell cycle);GO:0006368(transcription elongation from RNA polymerase II promoter);GO:0017162(aryl hydrocarbon receptor binding);GO:1901796(regulation of signal transduction by p53 class mediator);GO:0005669(transcription factor TFIID complex);GO:0033276(transcription factor TFTC complex);GO:0043234(protein complex);GO:0071339(MLL1 complex);GO:0042795(snRNA transcription from RNA polymerase II promoter);GO:0042795(snRNA transcription from RNA polymerase II promoter)","03022(Basal transcription factors);05168(Herpes simplex infection);05168(Herpes simplex infection)","K03131","NA","TATA-box binding protein associated factor 6 [Source:HGNC Symbol;Acc:HGNC:11540]",{"v":5.68375688228096,"d":"5.68"},{"v":3.42752743441018,"d":"3.43"},{"v":1.65826736358685,"d":"1.66"},{"v":0.729676632300434,"d":"0.73"},{"v":0.253580083611751,"d":"0.25"},1,"up","no"]
["MSTRG.14386","NCOA2","ENST00000452400;ENST00000522054;ENST00000518287;ENST00000519724;ENST00000521239;ENST00000520416;ENST00000524223;ENST00000518363","GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0003713(transcription coactivator activity);GO:0046983(protein dimerization activity);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0005515(protein binding);GO:0016604(nuclear body);GO:0048511(rhythmic process);GO:2000273(positive regulation of receptor activity);GO:0032870(cellular response to hormone stimulus);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0030374(ligand-dependent nuclear receptor transcription coactivator activity);GO:0035257(nuclear hormone receptor binding);GO:0017162(aryl hydrocarbon receptor binding);GO:0043234(protein complex);GO:0019904(protein domain specific binding);GO:0032922(circadian regulation of gene expression);GO:0019216(regulation of lipid metabolic process);GO:0015721(bile acid and bile salt transport);GO:0016922(ligand-dependent nuclear receptor binding);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:0001162(RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding);GO:0003682(chromatin binding);GO:0005102(receptor binding);GO:0008134(transcription factor binding);GO:0030375(thyroid hormone receptor coactivator activity);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0007623(circadian rhythm);GO:0010906(regulation of glucose metabolic process);GO:0030522(intracellular receptor signaling pathway);GO:0045475(locomotor rhythm);GO:0045892(negative regulation of transcription, DNA-templated);GO:1904017(cellular response to Thyroglobulin triiodothyronine);GO:0005737(cytoplasm);GO:0003677(DNA binding);GO:0003677(DNA binding)","04919(Thyroid hormone signaling pathway);04919(Thyroid hormone signaling pathway)","K11255","NA","nuclear receptor coactivator 2 [Source:HGNC Symbol;Acc:HGNC:7669]",{"v":5.06384485886695,"d":"5.06"},{"v":8.68014121803311,"d":"8.68"},{"v":0.583382773582847,"d":"0.58"},{"v":-0.77748530864017,"d":"-0.78"},{"v":0.254192595640488,"d":"0.25"},1,"down","no"]
["MSTRG.7198","ARMC7","ENST00000245543;ENST00000582136;ENST00000579096;ENST00000581078","GO:0005515(protein binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0045296(cadherin binding);GO:0019903(protein phosphatase binding);GO:0045294(alpha-catenin binding);GO:0016342(catenin complex);GO:0016342(catenin complex)","NA","NA","NA","armadillo repeat containing 7 [Source:HGNC Symbol;Acc:HGNC:26168]",{"v":3.11628527169678,"d":"3.12"},{"v":5.34973283740701,"d":"5.35"},{"v":0.582512317233252,"d":"0.58"},{"v":-0.779639538985756,"d":"-0.78"},{"v":0.255651200882972,"d":"0.26"},1,"down","no"]
["ENSG00000185344","ATP6V0A2","ENST00000330342;ENST00000544833;ENST00000534943;ENST00000613625;ENST00000504192;ENST00000545059;ENST00000543687","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005765(lysosomal membrane);GO:0006811(ion transport);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0006879(cellular iron ion homeostasis);GO:0015078(hydrogen ion transmembrane transporter activity);GO:0015991(ATP hydrolysis coupled proton transport);GO:0015992(proton transport);GO:0000220(vacuolar proton-transporting V-type ATPase, V0 domain);GO:0033179(proton-transporting V-type ATPase, V0 domain);GO:0005768(endosome);GO:0034220(ion transmembrane transport);GO:0010008(endosome membrane);GO:0030670(phagocytic vesicle membrane);GO:0006955(immune response);GO:0008286(insulin receptor signaling pathway);GO:0016241(regulation of macroautophagy);GO:0033572(transferrin transport);GO:0090383(phagosome acidification);GO:0036295(cellular response to increased oxygen levels);GO:0015986(ATP synthesis coupled proton transport);GO:0046961(proton-transporting ATPase activity, rotational mechanism);GO:0007035(vacuolar acidification);GO:0051117(ATPase binding);GO:0070072(vacuolar proton-transporting V-type ATPase complex assembly);GO:0016471(vacuolar proton-transporting V-type ATPase complex);GO:0001669(acrosomal vesicle);GO:0001669(acrosomal vesicle)","00190(Oxidative phosphorylation);04145(Phagosome);04142(Lysosome);04966(Collecting duct acid secretion);04721(Synaptic vesicle cycle);05323(Rheumatoid arthritis);05110(Vibrio cholerae infection);05120(Epithelial cell signaling in Helicobacter pylori infection);05152(Tuberculosis);05165(Human papillomavirus infection);05165(Human papillomavirus infection)","K02154","NA","ATPase H+ transporting V0 subunit a2 [Source:HGNC Symbol;Acc:HGNC:18481]",{"v":0.96125391011727,"d":"0.96"},{"v":0.580511385315755,"d":"0.58"},{"v":1.65587434533161,"d":"1.66"},{"v":0.727593199259355,"d":"0.73"},{"v":0.257101746441653,"d":"0.26"},1,"up","no"]
["MSTRG.14147","WDR86-AS1","ENST00000460148;ENST00000480632;ENST00000466677;ENST00000489632","NA","NA","NA","NA","WDR86 antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:41186]",{"v":1.12532558271787,"d":"1.13"},{"v":0.658720634416544,"d":"0.66"},{"v":1.70835028375059,"d":"1.71"},{"v":0.772603818528105,"d":"0.77"},{"v":0.25900245455954,"d":"0.26"},1,"up","no"]
["ENSG00000135862","LAMC1","ENST00000258341","GO:0007155(cell adhesion);GO:0005576(extracellular region);GO:0005578(proteinaceous extracellular matrix);GO:0005615(extracellular space);GO:0005604(basement membrane);GO:0070062(extracellular exosome);GO:0044267(cellular protein metabolic process);GO:0031012(extracellular matrix);GO:0043687(post-translational protein modification);GO:0005788(endoplasmic reticulum lumen);GO:0030198(extracellular matrix organization);GO:0016477(cell migration);GO:0034446(substrate adhesion-dependent cell spreading);GO:0043259(laminin-10 complex);GO:0043260(laminin-11 complex);GO:0007492(endoderm development);GO:0006461(protein complex assembly);GO:0050679(positive regulation of epithelial cell proliferation);GO:0005201(extracellular matrix structural constituent);GO:0005606(laminin-1 complex);GO:0022617(extracellular matrix disassembly);GO:0031581(hemidesmosome assembly);GO:0048731(system development);GO:0070831(basement membrane assembly)","04151(PI3K-Akt signaling pathway);04512(ECM-receptor interaction);04510(Focal adhesion);05200(Pathways in cancer);05222(Small cell lung cancer);05020(Prion diseases);05165(Human papillomavirus infection);05146(Amoebiasis);05145(Toxoplasmosis)","K05635","NA","laminin subunit gamma 1 [Source:HGNC Symbol;Acc:HGNC:6492]",{"v":0.39149279812039,"d":"0.39"},{"v":0.235168405900547,"d":"0.24"},{"v":1.6647338175433,"d":"1.66"},{"v":0.735291516149363,"d":"0.74"},{"v":0.260598967418323,"d":"0.26"},1,"up","no"]
["MSTRG.10958","ZMYND10","ENST00000231749;ENST00000360165;ENST00000468182;ENST00000478269;ENST00000442887;ENST00000431869;ENST00000490675;ENST00000475688","GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0005815(microtubule organizing center);GO:0036159(inner dynein arm assembly);GO:0044458(motile cilium assembly);GO:0034451(centriolar satellite);GO:0036158(outer dynein arm assembly);GO:0036158(outer dynein arm assembly)","NA","NA","NA","zinc finger MYND-type containing 10 [Source:HGNC Symbol;Acc:HGNC:19412]",{"v":0.384227256173609,"d":"0.38"},{"v":0.233764589673235,"d":"0.23"},{"v":1.64365037797511,"d":"1.64"},{"v":0.716903454978772,"d":"0.72"},{"v":0.261312180041127,"d":"0.26"},1,"up","no"]
["MSTRG.11048","RYBP","ENST00000477973","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0005654(nucleoplasm);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0006915(apoptotic process);GO:0007275(multicellular organism development);GO:0003714(transcription corepressor activity);GO:0031519(PcG protein complex);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0035518(histone H2A monoubiquitination)","NA","NA","NA","RING1 and YY1 binding protein [Source:HGNC Symbol;Acc:HGNC:10480]",{"v":5.61975,"d":"5.62"},{"v":9.550289,"d":"9.55"},{"v":0.588437690210213,"d":"0.59"},{"v":-0.765038438814817,"d":"-0.77"},{"v":0.261600701500679,"d":"0.26"},1,"down","no"]
["MSTRG.482","ZNF691","ENST00000372502;ENST00000372508;ENST00000372506;ENST00000630961;ENST00000372507;ENST00000372503;ENST00000397034","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0003677(DNA binding);GO:0003677(DNA binding)","NA","NA","NA","zinc finger protein 691 [Source:HGNC Symbol;Acc:HGNC:28028]",{"v":3.38462050147348,"d":"3.38"},{"v":2.04462944793713,"d":"2.04"},{"v":1.65537110154033,"d":"1.66"},{"v":0.727154677054175,"d":"0.73"},{"v":0.263924953025535,"d":"0.26"},1,"up","no"]
["MSTRG.6268","RFLNB","ENST00000329099","GO:0005737(cytoplasm);GO:0005856(cytoskeleton);GO:0031005(filamin binding);GO:0061181(regulation of chondrocyte development);GO:0061572(actin filament bundle organization);GO:0001837(epithelial to mesenchymal transition);GO:0030036(actin cytoskeleton organization);GO:0048705(skeletal system morphogenesis);GO:0061182(negative regulation of chondrocyte development);GO:1900158(negative regulation of bone mineralization involved in bone maturation);GO:0015629(actin cytoskeleton);GO:0032432(actin filament bundle)","NA","NA","NA","refilin B [Source:HGNC Symbol;Acc:HGNC:28705]",{"v":21.843237,"d":"21.84"},{"v":36.976059,"d":"36.98"},{"v":0.59073999746701,"d":"0.59"},{"v":-0.759404798495116,"d":"-0.76"},{"v":0.264725786001159,"d":"0.26"},1,"down","no"]
["ENSG00000061676","NCKAP1","ENST00000361354;ENST00000493359;ENST00000495619;ENST00000471640","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005886(plasma membrane);GO:0042995(cell projection);GO:0005515(protein binding);GO:0005925(focal adhesion);GO:0038096(Fc-gamma receptor signaling pathway involved in phagocytosis);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0016032(viral process);GO:0030027(lamellipodium);GO:0030838(positive regulation of actin filament polymerization);GO:0006915(apoptotic process);GO:0007417(central nervous system development);GO:0048010(vascular endothelial growth factor receptor signaling pathway);GO:0032403(protein complex binding);GO:0010592(positive regulation of lamellipodium assembly);GO:0001726(ruffle);GO:0048365(Rac GTPase binding);GO:0031258(lamellipodium membrane);GO:0016601(Rac protein signal transduction);GO:0031209(SCAR complex);GO:0031941(filamentous actin);GO:2000601(positive regulation of Arp2/3 complex-mediated actin nucleation);GO:2000601(positive regulation of Arp2/3 complex-mediated actin nucleation)","04810(Regulation of actin cytoskeleton);04810(Regulation of actin cytoskeleton)","K05750","NA","NCK associated protein 1 [Source:HGNC Symbol;Acc:HGNC:7666]",{"v":0.145195488010657,"d":"0.15"},{"v":0.250031380905861,"d":"0.25"},{"v":0.580709059337333,"d":"0.58"},{"v":-0.784112553942859,"d":"-0.78"},{"v":0.265762406104319,"d":"0.27"},1,"down","no"]
["ENSG00000101654","RNMT","ENST00000262173;ENST00000588457;ENST00000591922;ENST00000589866;ENST00000383314;ENST00000592764;ENST00000543302;ENST00000588417","GO:0005634(nucleus);GO:0003723(RNA binding);GO:0006397(mRNA processing);GO:0005654(nucleoplasm);GO:0008168(methyltransferase activity);GO:0016740(transferase activity);GO:0032259(methylation);GO:0001650(fibrillar center);GO:0005515(protein binding);GO:0005845(mRNA cap binding complex);GO:0006370(7-methylguanosine mRNA capping);GO:0004482(mRNA (guanine-N7-)-methyltransferase activity);GO:0106005(RNA 5'-cap (guanine-N7)-methylation);GO:0006366(transcription from RNA polymerase II promoter);GO:0043235(receptor complex);GO:0031533(mRNA cap methyltransferase complex);GO:1990830(cellular response to leukemia inhibitory factor);GO:1990830(cellular response to leukemia inhibitory factor)","03015(mRNA surveillance pathway);03015(mRNA surveillance pathway)","K00565","EC:2.1.1.56","RNA guanine-7 methyltransferase [Source:HGNC Symbol;Acc:HGNC:10075]",{"v":0.782114599398453,"d":"0.78"},{"v":0.473365650816385,"d":"0.47"},{"v":1.65224197837251,"d":"1.65"},{"v":0.724424991498916,"d":"0.72"},{"v":0.267141259397028,"d":"0.27"},1,"up","no"]
["MSTRG.4609","CCDC88C","ENST00000389857;ENST00000334448;MSTRG.4609.1;ENST00000553403;ENST00000553437;ENST00000554165;ENST00000557507;ENST00000554051;ENST00000389856;ENST00000554872;ENST00000556767;ENST00000555995;ENST00000557455","GO:0016055(Wnt signaling pathway);GO:0005737(cytoplasm);GO:0005813(centrosome);GO:0031648(protein destabilization);GO:0008017(microtubule binding);GO:0051959(dynein light intermediate chain binding);GO:0030705(cytoskeleton-dependent intracellular transport);GO:0031122(cytoplasmic microtubule organization);GO:0030165(PDZ domain binding);GO:0043621(protein self-association);GO:0001932(regulation of protein phosphorylation);GO:0051260(protein homooligomerization);GO:0031098(stress-activated protein kinase signaling cascade);GO:0031098(stress-activated protein kinase signaling cascade)","NA","NA","NA","coiled-coil domain containing 88C [Source:HGNC Symbol;Acc:HGNC:19967]",{"v":9.96715554554965,"d":"9.97"},{"v":6.12538663487848,"d":"6.13"},{"v":1.62718798659921,"d":"1.63"},{"v":0.702380933043475,"d":"0.70"},{"v":0.267756769224089,"d":"0.27"},1,"up","no"]
["MSTRG.2885","PCSK7","ENST00000534529;ENST00000528973;ENST00000320934;ENST00000532810;ENST00000528217;ENST00000532301;ENST00000524507;ENST00000529458;ENST00000533135;ENST00000527861;ENST00000527037;ENST00000525027;ENST00000531573","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016787(hydrolase activity);GO:0005794(Golgi apparatus);GO:0008233(peptidase activity);GO:0006508(proteolysis);GO:0004252(serine-type endopeptidase activity);GO:0008236(serine-type peptidase activity);GO:0030173(integral component of Golgi membrane);GO:0016486(peptide hormone processing);GO:0016485(protein processing);GO:0016485(protein processing)","NA","NA","NA","proprotein convertase subtilisin/kexin type 7 [Source:HGNC Symbol;Acc:HGNC:8748]",{"v":2.93363878496166,"d":"2.93"},{"v":1.80728959328341,"d":"1.81"},{"v":1.62322562795924,"d":"1.62"},{"v":0.698863548076743,"d":"0.70"},{"v":0.270081182842416,"d":"0.27"},1,"up","no"]
["MSTRG.11933","IRF2","ENST00000393593;ENST00000506230;ENST00000510814;ENST00000509274;ENST00000507523;ENST00000505067;ENST00000512020;ENST00000504340;ENST00000502750","GO:0005634(nucleus);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0006355(regulation of transcription, DNA-templated);GO:0006366(transcription from RNA polymerase II promoter);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0005925(focal adhesion);GO:0005515(protein binding);GO:0000975(regulatory region DNA binding);GO:0051607(defense response to virus);GO:0008283(cell proliferation);GO:0001228(transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0060333(interferon-gamma-mediated signaling pathway);GO:0000977(RNA polymerase II regulatory region sequence-specific DNA binding);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0060337(type I interferon signaling pathway);GO:0007596(blood coagulation);GO:0007596(blood coagulation)","NA","NA","NA","interferon regulatory factor 2 [Source:HGNC Symbol;Acc:HGNC:6117]",{"v":28.5200198847882,"d":"28.52"},{"v":47.9924047278562,"d":"47.99"},{"v":0.594261113743157,"d":"0.59"},{"v":-0.750831115495911,"d":"-0.75"},{"v":0.270394191976895,"d":"0.27"},1,"down","no"]
["MSTRG.6476","PIGL","ENST00000225609;ENST00000489009;ENST00000463810;ENST00000431149;ENST00000581006;ENST00000613719;ENST00000498772;ENST00000488375;ENST00000395844;ENST00000585034;ENST00000470116;ENST00000414755;ENST00000607144;ENST00000580201","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016787(hydrolase activity);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0006506(GPI anchor biosynthetic process);GO:0016254(preassembly of GPI anchor in ER membrane);GO:0000225(N-acetylglucosaminylphosphatidylinositol deacetylase activity);GO:0000225(N-acetylglucosaminylphosphatidylinositol deacetylase activity)","00563(Glycosylphosphatidylinositol(GPI)-anchor biosynthesis);00563(Glycosylphosphatidylinositol(GPI)-anchor biosynthesis)","K03434","EC:3.5.1.89","phosphatidylinositol glycan anchor biosynthesis class L [Source:HGNC Symbol;Acc:HGNC:8966]",{"v":0.465522208860759,"d":"0.47"},{"v":0.281896721518987,"d":"0.28"},{"v":1.65139277375173,"d":"1.65"},{"v":0.723683297326284,"d":"0.72"},{"v":0.272880052418301,"d":"0.27"},1,"up","no"]
["MSTRG.230","HNRNPR","ENST00000606561;ENST00000374616;ENST00000478691;ENST00000374612;ENST00000302271;ENST00000476451;ENST00000470941;ENST00000490652;ENST00000463552;ENST00000476660;ENST00000464516","GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0006397(mRNA processing);GO:0008380(RNA splicing);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005654(nucleoplasm);GO:0030529(intracellular ribonucleoprotein complex);GO:0005783(endoplasmic reticulum);GO:0005515(protein binding);GO:0005681(spliceosomal complex);GO:0043231(intracellular membrane-bounded organelle);GO:0000398(mRNA splicing, via spliceosome);GO:0016070(RNA metabolic process);GO:0071013(catalytic step 2 spliceosome);GO:0003730(mRNA 3'-UTR binding);GO:0007623(circadian rhythm);GO:0043086(negative regulation of catalytic activity);GO:0061014(positive regulation of mRNA catabolic process);GO:0061157(mRNA destabilization);GO:0030425(dendrite);GO:0030426(growth cone);GO:0043679(axon terminus);GO:0019013(viral nucleocapsid);GO:0019013(viral nucleocapsid)","NA","NA","NA","heterogeneous nuclear ribonucleoprotein R [Source:HGNC Symbol;Acc:HGNC:5047]",{"v":9.25297980525164,"d":"9.25"},{"v":5.7320711828861,"d":"5.73"},{"v":1.61424719094168,"d":"1.61"},{"v":0.690861516558371,"d":"0.69"},{"v":0.275028555578402,"d":"0.28"},1,"up","no"]
["MSTRG.1849","LIPA","ENST00000336233;ENST00000371837;ENST00000456827;ENST00000428800;ENST00000489359","GO:0043231(intracellular membrane-bounded organelle);GO:0016787(hydrolase activity);GO:0001650(fibrillar center);GO:0006629(lipid metabolic process);GO:0016042(lipid catabolic process);GO:0016788(hydrolase activity, acting on ester bonds);GO:0005764(lysosome);GO:0070062(extracellular exosome);GO:0043202(lysosomal lumen);GO:0034383(low-density lipoprotein particle clearance);GO:0016298(lipase activity);GO:0004771(sterol esterase activity);GO:0000902(cell morphogenesis);GO:0001816(cytokine production);GO:0006954(inflammatory response);GO:0008283(cell proliferation);GO:0030324(lung development);GO:0048771(tissue remodeling);GO:0048873(homeostasis of number of cells within a tissue);GO:0048873(homeostasis of number of cells within a tissue)","00100(Steroid biosynthesis);04142(Lysosome);04979(Cholesterol metabolism);04979(Cholesterol metabolism)","K01052","EC:3.1.1.13","lipase A, lysosomal acid type [Source:HGNC Symbol;Acc:HGNC:6617]",{"v":8.20156543645621,"d":"8.20"},{"v":13.7402546164969,"d":"13.74"},{"v":0.596900542629625,"d":"0.60"},{"v":-0.744437529575583,"d":"-0.74"},{"v":0.275437768893244,"d":"0.28"},1,"down","no"]
["ENSG00000251369","ZNF550","ENST00000447310;ENST00000344222;ENST00000601415;ENST00000595560;ENST00000325134;ENST00000457177","GO:0003676(nucleic acid binding);GO:0006355(regulation of transcription, DNA-templated);GO:0005622(intracellular);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0005515(protein binding)","NA","NA","NA","zinc finger protein 550 [Source:HGNC Symbol;Acc:HGNC:28643]",{"v":1.58937328484372,"d":"1.59"},{"v":0.979542957538824,"d":"0.98"},{"v":1.62256619029465,"d":"1.62"},{"v":0.698277332130161,"d":"0.70"},{"v":0.278310766975576,"d":"0.28"},1,"up","no"]
["MSTRG.2889","BACE1","ENST00000313005;ENST00000445823;ENST00000513780;ENST00000509916;ENST00000530824","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016787(hydrolase activity);GO:0005794(Golgi apparatus);GO:0005783(endoplasmic reticulum);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0008233(peptidase activity);GO:0006508(proteolysis);GO:0004190(aspartic-type endopeptidase activity);GO:0004175(endopeptidase activity);GO:0050435(amyloid-beta metabolic process);GO:0050804(modulation of synaptic transmission);GO:0005768(endosome);GO:0005802(trans-Golgi network);GO:0030424(axon);GO:0031410(cytoplasmic vesicle);GO:0030659(cytoplasmic vesicle membrane);GO:0045121(membrane raft);GO:0005887(integral component of plasma membrane);GO:0044267(cellular protein metabolic process);GO:0010008(endosome membrane);GO:0005770(late endosome);GO:0030163(protein catabolic process);GO:0019899(enzyme binding);GO:0009986(cell surface);GO:0005788(endoplasmic reticulum lumen);GO:0006509(membrane protein ectodomain proteolysis);GO:0005771(multivesicular body);GO:0001540(amyloid-beta binding);GO:0008798(beta-aspartyl-peptidase activity);GO:0070931(Golgi-associated vesicle lumen);GO:0070931(Golgi-associated vesicle lumen)","05010(Alzheimer's disease);05010(Alzheimer's disease)","K04521","EC:3.4.23.46","beta-secretase 1 [Source:HGNC Symbol;Acc:HGNC:933]",{"v":0.479171184422809,"d":"0.48"},{"v":0.803960212795549,"d":"0.80"},{"v":0.596013554895489,"d":"0.60"},{"v":-0.746582953196355,"d":"-0.75"},{"v":0.278671838667809,"d":"0.28"},1,"down","no"]
["ENSG00000113240","CLK4","ENST00000520878;ENST00000519583;ENST00000316308;ENST00000523013;ENST00000522136;ENST00000520957;ENST00000520199;ENST00000611575;ENST00000519132;ENST00000520126;ENST00000522749;ENST00000521621","GO:0005634(nucleus);GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0004713(protein tyrosine kinase activity);GO:0005515(protein binding);GO:0043484(regulation of RNA splicing);GO:0004712(protein serine/threonine/tyrosine kinase activity);GO:0018108(peptidyl-tyrosine phosphorylation);GO:0046777(protein autophosphorylation);GO:0046777(protein autophosphorylation)","NA","NA","NA","CDC like kinase 4 [Source:HGNC Symbol;Acc:HGNC:13659]",{"v":1.64314702877335,"d":"1.64"},{"v":2.74375012872287,"d":"2.74"},{"v":0.598869048450189,"d":"0.60"},{"v":-0.739687523935772,"d":"-0.74"},{"v":0.281396516641859,"d":"0.28"},1,"down","no"]
["MSTRG.13619","POLR2J4;AC004951.4;AC004951.2;AC004951.3","ENST00000326391;ENST00000427076;ENST00000422304;ENST00000454572;ENST00000420754;ENST00000418645;ENST00000418424","NA","NA","NA","NA","RNA polymerase II subunit J4, pseudogene [Source:HGNC Symbol;Acc:HGNC:28195]",{"v":1.28074774381745,"d":"1.28"},{"v":0.793956018884892,"d":"0.79"},{"v":1.61312177671536,"d":"1.61"},{"v":0.689855353578346,"d":"0.69"},{"v":0.282429338029932,"d":"0.28"},1,"up","no"]
["MSTRG.10072","AGPAT3","ENST00000291572;ENST00000467358;ENST00000484865;ENST00000398063;ENST00000445582;ENST00000474735;ENST00000398058;ENST00000479117;ENST00000398061;ENST00000481319;ENST00000327505;ENST00000448287","GO:0005634(nucleus);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016740(transferase activity);GO:0016746(transferase activity, transferring acyl groups);GO:0006629(lipid metabolic process);GO:0008152(metabolic process);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005886(plasma membrane);GO:0008654(phospholipid biosynthetic process);GO:0003841(1-acylglycerol-3-phosphate O-acyltransferase activity);GO:0016024(CDP-diacylglycerol biosynthetic process);GO:0000139(Golgi membrane);GO:0005635(nuclear envelope);GO:0006654(phosphatidic acid biosynthetic process);GO:0042171(lysophosphatidic acid acyltransferase activity);GO:0042171(lysophosphatidic acid acyltransferase activity)","00561(Glycerolipid metabolism);00564(Glycerophospholipid metabolism);04072(Phospholipase D signaling pathway);04072(Phospholipase D signaling pathway)","K13523","EC:2.3.1.51;EC:2.3.1.-","1-acylglycerol-3-phosphate O-acyltransferase 3 [Source:HGNC Symbol;Acc:HGNC:326]",{"v":0.977179754160765,"d":"0.98"},{"v":1.62596912393768,"d":"1.63"},{"v":0.600982970570982,"d":"0.60"},{"v":-0.734603983519741,"d":"-0.73"},{"v":0.284184540287813,"d":"0.28"},1,"down","no"]
["MSTRG.6884","HDAC5","ENST00000225983;MSTRG.6884.4;ENST00000586802;ENST00000593013;ENST00000591714;ENST00000586339;ENST00000588261;ENST00000336057;ENST00000592385;ENST00000587135;ENST00000588419;ENST00000587776","GO:0051091(positive regulation of sequence-specific DNA binding transcription factor activity);GO:0010832(negative regulation of myotube differentiation);GO:0090051(negative regulation of cell migration involved in sprouting angiogenesis);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0005737(cytoplasm);GO:0005634(nucleus);GO:0016607(nuclear speck);GO:0005794(Golgi apparatus);GO:0046872(metal ion binding);GO:0005829(cytosol);GO:0004407(histone deacetylase activity);GO:0016787(hydrolase activity);GO:0032041(NAD-dependent histone deacetylase activity (H3-K14 specific));GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0016569(covalent chromatin modification);GO:0070932(histone H3 deacetylation);GO:0006476(protein deacetylation);GO:0005515(protein binding);GO:0006325(chromatin organization);GO:0006954(inflammatory response);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0001047(core promoter binding);GO:0005654(nucleoplasm);GO:0016575(histone deacetylation);GO:0042113(B cell activation);GO:0000118(histone deacetylase complex);GO:0040029(regulation of gene expression, epigenetic);GO:0045892(negative regulation of transcription, DNA-templated);GO:0044212(transcription regulatory region DNA binding);GO:0008134(transcription factor binding);GO:0033558(protein deacetylase activity);GO:0042826(histone deacetylase binding);GO:0032869(cellular response to insulin stimulus);GO:0006338(chromatin remodeling);GO:0030183(B cell differentiation);GO:0005080(protein kinase C binding);GO:0043393(regulation of protein binding);GO:0070491(repressing transcription factor binding);GO:0001025(RNA polymerase III transcription factor binding);GO:0010830(regulation of myotube differentiation);GO:0006342(chromatin silencing);GO:0003682(chromatin binding);GO:0014823(response to activity);GO:0030182(neuron differentiation);GO:0042220(response to cocaine);GO:0042493(response to drug);GO:0071222(cellular response to lipopolysaccharide);GO:0043234(protein complex);GO:0043234(protein complex)","04371(Apelin signaling pathway);05203(Viral carcinogenesis);05034(Alcoholism);05169(Epstein-Barr virus infection);05165(Human papillomavirus infection);05165(Human papillomavirus infection)","K11406","EC:3.5.1.98","histone deacetylase 5 [Source:HGNC Symbol;Acc:HGNC:14068]",{"v":5.85709706274613,"d":"5.86"},{"v":9.70404062299816,"d":"9.70"},{"v":0.603573015643098,"d":"0.60"},{"v":-0.728399787147535,"d":"-0.73"},{"v":0.286126957598916,"d":"0.29"},1,"down","no"]
["MSTRG.3238","EPS8","ENST00000281172;ENST00000535734;ENST00000508018;ENST00000545610;ENST00000541465","GO:0003779(actin binding);GO:0035591(signaling adaptor activity);GO:0009967(positive regulation of signal transduction);GO:0051016(barbed-end actin filament capping);GO:0051017(actin filament bundle assembly);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005886(plasma membrane);GO:0042995(cell projection);GO:0005515(protein binding);GO:0030054(cell junction);GO:0045202(synapse);GO:0030426(growth cone);GO:0070062(extracellular exosome);GO:0005938(cell cortex);GO:0032587(ruffle membrane);GO:0032420(stereocilium);GO:0008360(regulation of cell shape);GO:0043005(neuron projection);GO:0007165(signal transduction);GO:0031982(vesicle);GO:0008283(cell proliferation);GO:0010458(exit from mitosis);GO:0005070(SH3/SH2 adaptor activity);GO:0007173(epidermal growth factor receptor signaling pathway);GO:0048365(Rac GTPase binding);GO:0030832(regulation of actin filament length);GO:0016601(Rac protein signal transduction);GO:0070358(actin polymerization-dependent cell motility);GO:0036336(dendritic cell migration);GO:0051764(actin crosslink formation);GO:0008344(adult locomotory behavior);GO:0031532(actin cytoskeleton reorganization);GO:0048149(behavioral response to ethanol);GO:1990830(cellular response to leukemia inhibitory factor);GO:0005903(brush border);GO:0014069(postsynaptic density);GO:0017146(NMDA selective glutamate receptor complex);GO:0017146(NMDA selective glutamate receptor complex)","NA","NA","NA","epidermal growth factor receptor pathway substrate 8 [Source:HGNC Symbol;Acc:HGNC:3420]",{"v":0.226100253387097,"d":"0.23"},{"v":0.382612669677419,"d":"0.38"},{"v":0.590937706212714,"d":"0.59"},{"v":-0.758922038384229,"d":"-0.76"},{"v":0.286647092713912,"d":"0.29"},1,"down","no"]
["ENSG00000278195","SSTR3","ENST00000610913;ENST00000617123","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0004930(G-protein coupled receptor activity);GO:0007186(G-protein coupled receptor signaling pathway);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0004871(signal transducer activity);GO:0007165(signal transduction);GO:0005887(integral component of plasma membrane);GO:0043005(neuron projection);GO:0007267(cell-cell signaling);GO:0007268(chemical synaptic transmission);GO:0008285(negative regulation of cell proliferation);GO:0007218(neuropeptide signaling pathway);GO:0008628(hormone-mediated apoptotic signaling pathway);GO:0007187(G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger);GO:0060170(ciliary membrane);GO:0004994(somatostatin receptor activity);GO:0042923(neuropeptide binding);GO:0038170(somatostatin signaling pathway);GO:0005102(receptor binding);GO:0007283(spermatogenesis);GO:0021549(cerebellum development);GO:0030900(forebrain development);GO:0042594(response to starvation);GO:0071385(cellular response to glucocorticoid stimulus);GO:0071392(cellular response to estradiol stimulus);GO:0005737(cytoplasm);GO:0005929(cilium);GO:0097730(non-motile cilium);GO:0097730(non-motile cilium)","04080(Neuroactive ligand-receptor interaction);04080(Neuroactive ligand-receptor interaction)","K04219","NA","somatostatin receptor 3 [Source:HGNC Symbol;Acc:HGNC:11332]",{"v":0.706135899137359,"d":"0.71"},{"v":0.436787392169874,"d":"0.44"},{"v":1.61665815404931,"d":"1.62"},{"v":0.693014649995196,"d":"0.69"},{"v":0.288328385930021,"d":"0.29"},1,"up","no"]
["ENSG00000113924","HGD","ENST00000492108;ENST00000480862;ENST00000283871;ENST00000466528;ENST00000470321;ENST00000494453;ENST00000475447","GO:0046872(metal ion binding);GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0005515(protein binding);GO:0051213(dioxygenase activity);GO:0006559(L-phenylalanine catabolic process);GO:0042802(identical protein binding);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0004411(homogentisate 1,2-dioxygenase activity);GO:0006570(tyrosine metabolic process);GO:0006572(tyrosine catabolic process);GO:0006520(cellular amino acid metabolic process);GO:0006520(cellular amino acid metabolic process)","00350(Tyrosine metabolism);00350(Tyrosine metabolism)","K00451","EC:1.13.11.5","homogentisate 1,2-dioxygenase [Source:HGNC Symbol;Acc:HGNC:4892]",{"v":0.602840860543077,"d":"0.60"},{"v":1.00929031277238,"d":"1.01"},{"v":0.597291832601818,"d":"0.60"},{"v":-0.743492100456551,"d":"-0.74"},{"v":0.288973586963565,"d":"0.29"},1,"down","no"]
["MSTRG.6773","FBXL20","ENST00000264658;ENST00000581781;ENST00000394294;ENST00000577399;ENST00000583610","GO:0005737(cytoplasm);GO:0005515(protein binding);GO:0005829(cytosol);GO:0000209(protein polyubiquitination);GO:0043687(post-translational protein modification);GO:0004842(ubiquitin-protein transferase activity);GO:0001662(behavioral fear response);GO:0001662(behavioral fear response)","NA","NA","NA","F-box and leucine rich repeat protein 20 [Source:HGNC Symbol;Acc:HGNC:24679]",{"v":1.33341140822613,"d":"1.33"},{"v":2.2012936075376,"d":"2.20"},{"v":0.605739917501375,"d":"0.61"},{"v":-0.723229608569096,"d":"-0.72"},{"v":0.290397327150304,"d":"0.29"},1,"down","no"]
["ENSG00000135336","ORC3","ENST00000392844;ENST00000468486;ENST00000508875;ENST00000257789;ENST00000478028","GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0016604(nuclear body);GO:0006260(DNA replication);GO:0005664(nuclear origin of replication recognition complex);GO:0000784(nuclear chromosome, telomeric region);GO:0000082(G1/S transition of mitotic cell cycle);GO:0006270(DNA replication initiation);GO:0003688(DNA replication origin binding);GO:0000808(origin recognition complex);GO:0006267(pre-replicative complex assembly involved in nuclear cell cycle DNA replication);GO:0005656(nuclear pre-replicative complex);GO:0031261(DNA replication preinitiation complex);GO:0061351(neural precursor cell proliferation);GO:0061351(neural precursor cell proliferation)","04110(Cell cycle);04110(Cell cycle)","K02605","NA","origin recognition complex subunit 3 [Source:HGNC Symbol;Acc:HGNC:8489]",{"v":2.849037640553,"d":"2.85"},{"v":1.78319605584169,"d":"1.78"},{"v":1.59771418920519,"d":"1.60"},{"v":0.676009351510504,"d":"0.68"},{"v":0.291478560160103,"d":"0.29"},1,"up","no"]
["ENSG00000047648","ARHGAP6","ENST00000380736;ENST00000380718;ENST00000489330;ENST00000495242;ENST00000491514","GO:0005737(cytoplasm);GO:0051497(negative regulation of stress fiber assembly);GO:0007015(actin filament organization);GO:0007165(signal transduction);GO:0009967(positive regulation of signal transduction);GO:0005096(GTPase activator activity);GO:0043087(regulation of GTPase activity);GO:0005829(cytosol);GO:0051056(regulation of small GTPase mediated signal transduction);GO:0017124(SH3 domain binding);GO:0030041(actin filament polymerization);GO:0015629(actin cytoskeleton);GO:0007266(Rho protein signal transduction);GO:0005884(actin filament);GO:0005070(SH3/SH2 adaptor activity);GO:0051895(negative regulation of focal adhesion assembly);GO:0043547(positive regulation of GTPase activity);GO:0048041(focal adhesion assembly);GO:0048041(focal adhesion assembly)","NA","NA","NA","Rho GTPase activating protein 6 [Source:HGNC Symbol;Acc:HGNC:676]",{"v":0.507539569689283,"d":"0.51"},{"v":0.8414201950539,"d":"0.84"},{"v":0.603193948365799,"d":"0.60"},{"v":-0.72930614026362,"d":"-0.73"},{"v":0.29278482851144,"d":"0.29"},1,"down","no"]
["ENSG00000116016","EPAS1","ENST00000263734;ENST00000467888;ENST00000463191;ENST00000466465;ENST00000483692","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0046983(protein dimerization activity);GO:0006355(regulation of transcription, DNA-templated);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0005667(transcription factor complex);GO:0016607(nuclear speck);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0007275(multicellular organism development);GO:0030154(cell differentiation);GO:0016567(protein ubiquitination);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0043687(post-translational protein modification);GO:0061418(regulation of transcription from RNA polymerase II promoter in response to hypoxia);GO:0000981(RNA polymerase II transcription factor activity, sequence-specific DNA binding);GO:0046982(protein heterodimerization activity);GO:0007165(signal transduction);GO:0006366(transcription from RNA polymerase II promoter);GO:0001525(angiogenesis);GO:0071456(cellular response to hypoxia);GO:0043565(sequence-specific DNA binding);GO:0035019(somatic stem cell population maintenance);GO:0008134(transcription factor binding);GO:0035035(histone acetyltransferase binding);GO:0001666(response to hypoxia);GO:0001077(transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0001892(embryonic placenta development);GO:0001974(blood vessel remodeling);GO:0002027(regulation of heart rate);GO:0006979(response to oxidative stress);GO:0007005(mitochondrion organization);GO:0007601(visual perception);GO:0030097(hemopoiesis);GO:0030218(erythrocyte differentiation);GO:0030324(lung development);GO:0042415(norepinephrine metabolic process);GO:0043129(surfactant homeostasis);GO:0043619(regulation of transcription from RNA polymerase II promoter in response to oxidative stress);GO:0048469(cell maturation);GO:0048625(myoblast fate commitment);GO:0055072(iron ion homeostasis);GO:0055072(iron ion homeostasis)","05200(Pathways in cancer);05211(Renal cell carcinoma);05211(Renal cell carcinoma)","K09095","NA","endothelial PAS domain protein 1 [Source:HGNC Symbol;Acc:HGNC:3374]",{"v":0.280662480964119,"d":"0.28"},{"v":0.472077765817584,"d":"0.47"},{"v":0.594525947389291,"d":"0.59"},{"v":-0.750188318805486,"d":"-0.75"},{"v":0.294664235849241,"d":"0.29"},1,"down","no"]
["MSTRG.191","LINC01772","ENST00000457898","NA","NA","NA","NA","long intergenic non-protein coding RNA 1772 [Source:HGNC Symbol;Acc:HGNC:52562]",{"v":0.352712,"d":"0.35"},{"v":0.211199,"d":"0.21"},{"v":1.67004578620164,"d":"1.67"},{"v":0.739887656364324,"d":"0.74"},{"v":0.295496046443786,"d":"0.30"},1,"up","no"]
["MSTRG.10356","AC003681.1;HORMAD2-AS1","ENST00000624945;ENST00000432568;ENST00000429350","NA","NA","NA","NA","HORMAD2 and MTMR3 antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:50729]",{"v":0.198799809222856,"d":"0.20"},{"v":0.325928375054827,"d":"0.33"},{"v":0.609949376728597,"d":"0.61"},{"v":-0.713238584954922,"d":"-0.71"},{"v":0.296869511003235,"d":"0.30"},1,"down","no"]
["MSTRG.5336","TMED3","ENST00000299705;ENST00000424155;ENST00000543455;ENST00000536821;ENST00000558562","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0015031(protein transport);GO:0005794(Golgi apparatus);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0031410(cytoplasmic vesicle);GO:0032580(Golgi cisterna membrane);GO:0030663(COPI-coated vesicle membrane);GO:0030126(COPI vesicle coat);GO:0006890(retrograde vesicle-mediated transport, Golgi to ER);GO:0006888(ER to Golgi vesicle-mediated transport);GO:0000139(Golgi membrane);GO:0030133(transport vesicle);GO:0033116(endoplasmic reticulum-Golgi intermediate compartment membrane);GO:0005793(endoplasmic reticulum-Golgi intermediate compartment);GO:0005793(endoplasmic reticulum-Golgi intermediate compartment)","NA","NA","NA","transmembrane p24 trafficking protein 3 [Source:HGNC Symbol;Acc:HGNC:28889]",{"v":0.687515649974319,"d":"0.69"},{"v":0.433005062660503,"d":"0.43"},{"v":1.58777739398711,"d":"1.59"},{"v":0.667008661156832,"d":"0.67"},{"v":0.297395260157777,"d":"0.30"},1,"up","no"]
["MSTRG.11404","RFC4","ENST00000479307;ENST00000494047;ENST00000433496;ENST00000460408;ENST00000296273;ENST00000418288;ENST00000427785;ENST00000392481;ENST00000448497;ENST00000447345","GO:0005524(ATP binding);GO:0003677(DNA binding);GO:0006260(DNA replication);GO:0005634(nucleus);GO:0000166(nucleotide binding);GO:0005515(protein binding);GO:0005654(nucleoplasm);GO:1901796(regulation of signal transduction by p53 class mediator);GO:0019985(translesion synthesis);GO:0006283(transcription-coupled nucleotide-excision repair);GO:0006281(DNA repair);GO:0042276(error-prone translesion synthesis);GO:0043142(single-stranded DNA-dependent ATPase activity);GO:0042769(DNA damage response, detection of DNA damage);GO:0006296(nucleotide-excision repair, DNA incision, 5'-to lesion);GO:0033683(nucleotide-excision repair, DNA incision);GO:0032201(telomere maintenance via semi-conservative replication);GO:0003689(DNA clamp loader activity);GO:1900264(positive regulation of DNA-directed DNA polymerase activity);GO:0031390(Ctf18 RFC-like complex);GO:0006297(nucleotide-excision repair, DNA gap filling);GO:0070987(error-free translesion synthesis);GO:0005663(DNA replication factor C complex);GO:0006271(DNA strand elongation involved in DNA replication);GO:0019899(enzyme binding);GO:0019899(enzyme binding)","03030(DNA replication);03420(Nucleotide excision repair);03430(Mismatch repair);03430(Mismatch repair)","K10755","NA","replication factor C subunit 4 [Source:HGNC Symbol;Acc:HGNC:9972]",{"v":1.01396923890557,"d":"1.01"},{"v":0.629487056389723,"d":"0.63"},{"v":1.61078647863064,"d":"1.61"},{"v":0.687765267081931,"d":"0.69"},{"v":0.299393171070323,"d":"0.30"},1,"up","no"]
["MSTRG.10685","FGD5-AS1","ENST00000426200;ENST00000424349;ENST00000430166;ENST00000440079;ENST00000417835","NA","NA","NA","NA","FGD5 antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:40410]",{"v":4.66465282167219,"d":"4.66"},{"v":7.62067178015981,"d":"7.62"},{"v":0.612105199677602,"d":"0.61"},{"v":-0.708148471364305,"d":"-0.71"},{"v":0.301069752222921,"d":"0.30"},1,"down","no"]
["MSTRG.8795","ANXA4","MSTRG.8795.1;MSTRG.8795.4;MSTRG.8795.3;MSTRG.8795.2","NA","NA","NA","NA",null,{"v":6.35765990479705,"d":"6.36"},{"v":10.4053190634686,"d":"10.41"},{"v":0.611000956916138,"d":"0.61"},{"v":-0.710753455371858,"d":"-0.71"},{"v":0.301742409424514,"d":"0.30"},1,"down","no"]
["MSTRG.6242","ANKRD11","ENST00000567736;ENST00000301030;ENST00000562275;ENST00000564553;ENST00000378332;ENST00000566973;ENST00000613312;ENST00000566858;ENST00000567699;ENST00000378330;ENST00000623388;ENST00000568512;ENST00000562816;ENST00000568100;ENST00000330736;ENST00000562194","GO:0005634(nucleus);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0005886(plasma membrane);GO:0042475(odontogenesis of dentin-containing tooth);GO:0048705(skeletal system morphogenesis);GO:0060325(face morphogenesis);GO:0001701(in utero embryonic development);GO:0001894(tissue homeostasis);GO:0035264(multicellular organism growth);GO:0060323(head morphogenesis);GO:0060348(bone development);GO:0060348(bone development)","NA","NA","NA","ankyrin repeat domain 11 [Source:HGNC Symbol;Acc:HGNC:21316]",{"v":2.50232947442327,"d":"2.50"},{"v":4.07692079273113,"d":"4.08"},{"v":0.613779271572985,"d":"0.61"},{"v":-0.704208170659738,"d":"-0.70"},{"v":0.303496719872347,"d":"0.30"},1,"down","no"]
["MSTRG.15398","PSMD10","ENST00000217958;ENST00000372295;ENST00000553388;ENST00000361815;ENST00000338548","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0045111(intermediate filament cytoskeleton);GO:0005515(protein binding);GO:0000502(proteasome complex);GO:0006915(apoptotic process);GO:0038095(Fc-epsilon receptor signaling pathway);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0005654(nucleoplasm);GO:0000165(MAPK cascade);GO:0000209(protein polyubiquitination);GO:0002223(stimulatory C-type lectin receptor signaling pathway);GO:0002479(antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent);GO:0006521(regulation of cellular amino acid metabolic process);GO:0010972(negative regulation of G2/M transition of mitotic cell cycle);GO:0016579(protein deubiquitination);GO:0031145(anaphase-promoting complex-dependent catabolic process);GO:0031146(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process);GO:0033209(tumor necrosis factor-mediated signaling pathway);GO:0038061(NIK/NF-kappaB signaling);GO:0043161(proteasome-mediated ubiquitin-dependent protein catabolic process);GO:0043488(regulation of mRNA stability);GO:0043687(post-translational protein modification);GO:0050852(T cell receptor signaling pathway);GO:0051437(positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition);GO:0055085(transmembrane transport);GO:0060071(Wnt signaling pathway, planar cell polarity pathway);GO:0061418(regulation of transcription from RNA polymerase II promoter in response to hypoxia);GO:0090090(negative regulation of canonical Wnt signaling pathway);GO:0090263(positive regulation of canonical Wnt signaling pathway);GO:1902036(regulation of hematopoietic stem cell differentiation);GO:0032088(negative regulation of NF-kappaB transcription factor activity);GO:0031398(positive regulation of protein ubiquitination);GO:0043066(negative regulation of apoptotic process);GO:0008134(transcription factor binding);GO:0051436(negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle);GO:0005838(proteasome regulatory particle);GO:0008540(proteasome regulatory particle, base subcomplex);GO:0070682(proteasome regulatory particle assembly);GO:0030307(positive regulation of cell growth);GO:0090201(negative regulation of release of cytochrome c from mitochondria);GO:0007253(cytoplasmic sequestering of NF-kappaB);GO:0032436(positive regulation of proteasomal ubiquitin-dependent protein catabolic process);GO:0043409(negative regulation of MAPK cascade);GO:0043518(negative regulation of DNA damage response, signal transduction by p53 class mediator);GO:0045737(positive regulation of cyclin-dependent protein serine/threonine kinase activity);GO:0045737(positive regulation of cyclin-dependent protein serine/threonine kinase activity)","NA","NA","NA","proteasome 26S subunit, non-ATPase 10 [Source:HGNC Symbol;Acc:HGNC:9555]",{"v":1.22614845302969,"d":"1.23"},{"v":2.01865618625457,"d":"2.02"},{"v":0.607408265646611,"d":"0.61"},{"v":-0.719261553971325,"d":"-0.72"},{"v":0.304153844257039,"d":"0.30"},1,"down","no"]
["MSTRG.4112","LAMP1","ENST00000332556;ENST00000472564","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005829(cytosol);GO:0005765(lysosomal membrane);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0048471(perinuclear region of cytoplasm);GO:0005764(lysosome);GO:0019904(protein domain specific binding);GO:0048102(autophagic cell death);GO:0050821(protein stabilization);GO:0005768(endosome);GO:0005770(late endosome);GO:0005771(multivesicular body);GO:0005773(vacuole);GO:0008021(synaptic vesicle);GO:0009897(external side of plasma membrane);GO:0009986(cell surface);GO:0030425(dendrite);GO:0031410(cytoplasmic vesicle);GO:0031982(vesicle);GO:0042383(sarcolemma);GO:0042470(melanosome);GO:0043025(neuronal cell body);GO:0044194(cytolytic granule);GO:0044754(autolysosome);GO:0045335(phagocytic vesicle);GO:0061474(phagolysosome membrane);GO:0097208(alveolar lamellar body);GO:0046718(viral entry into host cell);GO:0070062(extracellular exosome);GO:0010008(endosome membrane);GO:0016032(viral process);GO:0005887(integral component of plasma membrane);GO:0043312(neutrophil degranulation);GO:0019899(enzyme binding);GO:0005737(cytoplasm);GO:0035577(azurophil granule membrane);GO:0001618(virus receptor activity);GO:0101003(ficolin-1-rich granule membrane);GO:0043323(positive regulation of natural killer cell degranulation);GO:0045954(positive regulation of natural killer cell mediated cytotoxicity);GO:0090160(Golgi to lysosome transport);GO:0008626(granzyme-mediated apoptotic signaling pathway);GO:0072594(establishment of protein localization to organelle);GO:1902513(regulation of organelle transport along microtubule);GO:1902513(regulation of organelle transport along microtubule)","04145(Phagosome);04142(Lysosome);04140(Autophagy - animal);05152(Tuberculosis);05152(Tuberculosis)","K06528","NA","lysosomal associated membrane protein 1 [Source:HGNC Symbol;Acc:HGNC:6499]",{"v":13.7442292676424,"d":"13.74"},{"v":22.3161633340303,"d":"22.32"},{"v":0.615886748179674,"d":"0.62"},{"v":-0.699263008351688,"d":"-0.70"},{"v":0.305598174378971,"d":"0.31"},1,"down","no"]
["MSTRG.14756","GLIPR2","ENST00000377959;ENST00000474050;ENST00000619700;ENST00000377960;ENST00000396613","GO:0005576(extracellular region);GO:0016020(membrane);GO:0005794(Golgi apparatus);GO:0042803(protein homodimerization activity);GO:0000139(Golgi membrane);GO:0070062(extracellular exosome);GO:0070374(positive regulation of ERK1 and ERK2 cascade);GO:0010718(positive regulation of epithelial to mesenchymal transition);GO:0010634(positive regulation of epithelial cell migration);GO:0010634(positive regulation of epithelial cell migration)","NA","NA","NA","GLI pathogenesis related 2 [Source:HGNC Symbol;Acc:HGNC:18007]",{"v":21.5936061201309,"d":"21.59"},{"v":34.9548245754501,"d":"34.95"},{"v":0.617757530824423,"d":"0.62"},{"v":-0.694887401932534,"d":"-0.69"},{"v":0.309117687546225,"d":"0.31"},1,"down","no"]
["MSTRG.1953",null,"MSTRG.1953.1","NA","NA","NA","NA",null,{"v":5.230971,"d":"5.23"},{"v":8.507232,"d":"8.51"},{"v":0.614885194150107,"d":"0.61"},{"v":-0.701611026373375,"d":"-0.70"},{"v":0.309644871522112,"d":"0.31"},1,"down","no"]
["ENSG00000014257","ACPP","ENST00000336375;ENST00000351273;ENST00000512463;ENST00000483689","GO:0005634(nucleus);GO:0016020(membrane);GO:0016787(hydrolase activity);GO:0005765(lysosomal membrane);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0005615(extracellular space);GO:0003993(acid phosphatase activity);GO:0008253(5'-nucleotidase activity);GO:0005764(lysosome);GO:0042802(identical protein binding);GO:0070062(extracellular exosome);GO:0005622(intracellular);GO:0016311(dephosphorylation);GO:0043312(neutrophil degranulation);GO:0035577(azurophil granule membrane);GO:0042803(protein homodimerization activity);GO:0016791(phosphatase activity);GO:0051289(protein homotetramerization);GO:0051930(regulation of sensory perception of pain);GO:0042131(thiamine phosphate phosphatase activity);GO:0052642(lysophosphatidic acid phosphatase activity);GO:0006772(thiamine metabolic process);GO:0046085(adenosine metabolic process);GO:0060168(positive regulation of adenosine receptor signaling pathway);GO:0012506(vesicle membrane);GO:0006144(purine nucleobase metabolic process);GO:0009117(nucleotide metabolic process);GO:0016021(integral component of membrane);GO:0030175(filopodium);GO:0030175(filopodium)","NA","NA","NA","acid phosphatase, prostate [Source:HGNC Symbol;Acc:HGNC:125]",{"v":0.802826751252087,"d":"0.80"},{"v":1.3133903081326,"d":"1.31"},{"v":0.611262886805948,"d":"0.61"},{"v":-0.710135119223219,"d":"-0.71"},{"v":0.310629686340888,"d":"0.31"},1,"down","no"]
["ENSG00000104231","ZFAND1","ENST00000220669;ENST00000519820;ENST00000517588;ENST00000517450;ENST00000517353;ENST00000523431;ENST00000520941;ENST00000520076;ENST00000519523;ENST00000523096;ENST00000524339;ENST00000524305;ENST00000522520;ENST00000521885;ENST00000519464;ENST00000520604;ENST00000519338;ENST00000523012;ENST00000520635;ENST00000521287;ENST00000522032","GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0046872(metal ion binding)","NA","NA","NA","zinc finger AN1-type containing 1 [Source:HGNC Symbol;Acc:HGNC:25858]",{"v":2.42945339511153,"d":"2.43"},{"v":1.55056824988135,"d":"1.55"},{"v":1.56681487273935,"d":"1.57"},{"v":0.647834728018014,"d":"0.65"},{"v":0.311321042328344,"d":"0.31"},1,"up","no"]
["MSTRG.8932","MAL","ENST00000309988;ENST00000489399;ENST00000354078;ENST00000353004","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005783(endoplasmic reticulum);GO:0005515(protein binding);GO:0006915(apoptotic process);GO:0030154(cell differentiation);GO:0045121(membrane raft);GO:0019911(structural constituent of myelin sheath);GO:0042552(myelination);GO:1902043(positive regulation of extrinsic apoptotic signaling pathway via death domain receptors);GO:0019898(extrinsic component of membrane);GO:0008289(lipid binding);GO:0016324(apical plasma membrane);GO:0016505(peptidase activator activity involved in apoptotic process);GO:0007417(central nervous system development);GO:0001766(membrane raft polarization);GO:0045176(apical protein localization);GO:0045176(apical protein localization)","NA","NA","NA","mal, T-cell differentiation protein [Source:HGNC Symbol;Acc:HGNC:6817]",{"v":7.78793889636239,"d":"7.79"},{"v":4.98381901098147,"d":"4.98"},{"v":1.56264480696475,"d":"1.56"},{"v":0.643989887445063,"d":"0.64"},{"v":0.313239398597382,"d":"0.31"},1,"up","no"]
["MSTRG.4656","PAPOLA","ENST00000392990;ENST00000557320;ENST00000216277;ENST00000556459;ENST00000555021;ENST00000553940;ENST00000556248;ENST00000555701;ENST00000553689;ENST00000556283;ENST00000556619;ENST00000555508;ENST00000553461;ENST00000554130;ENST00000554666;ENST00000555912;ENST00000555626;ENST00000554135;ENST00000556787;ENST00000557406;ENST00000555224;ENST00000557471;ENST00000554887;ENST00000555131","GO:0005634(nucleus);GO:0003723(RNA binding);GO:0006397(mRNA processing);GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0005654(nucleoplasm);GO:0016740(transferase activity);GO:0016779(nucleotidyltransferase activity);GO:0000287(magnesium ion binding);GO:0004652(polynucleotide adenylyltransferase activity);GO:0031123(RNA 3'-end processing);GO:0043631(RNA polyadenylation);GO:0005515(protein binding);GO:0006369(termination of RNA polymerase II transcription);GO:0031124(mRNA 3'-end processing);GO:0000398(mRNA splicing, via spliceosome);GO:0006378(mRNA polyadenylation);GO:0031440(regulation of mRNA 3'-end processing);GO:0030145(manganese ion binding);GO:0030145(manganese ion binding)","03015(mRNA surveillance pathway);03015(mRNA surveillance pathway)","K14376","EC:2.7.7.19","poly(A) polymerase alpha [Source:HGNC Symbol;Acc:HGNC:14981]",{"v":7.09519318055773,"d":"7.10"},{"v":11.4337354942034,"d":"11.43"},{"v":0.620549004667355,"d":"0.62"},{"v":-0.688382950609146,"d":"-0.69"},{"v":0.313501385959617,"d":"0.31"},1,"down","no"]
["MSTRG.4300","COCH","ENST00000396618;ENST00000553833;ENST00000216361;ENST00000557065;ENST00000555117","GO:0007605(sensory perception of sound);GO:0005576(extracellular region);GO:0005578(proteinaceous extracellular matrix);GO:0031012(extracellular matrix);GO:0042742(defense response to bacterium);GO:0005515(protein binding);GO:0070062(extracellular exosome);GO:0008360(regulation of cell shape);GO:0045089(positive regulation of innate immune response);GO:0005518(collagen binding);GO:0005518(collagen binding)","NA","NA","NA","cochlin [Source:HGNC Symbol;Acc:HGNC:2180]",{"v":0.371234971554819,"d":"0.37"},{"v":0.23301224634079,"d":"0.23"},{"v":1.59319940211156,"d":"1.59"},{"v":0.671926843406976,"d":"0.67"},{"v":0.3157002599114,"d":"0.32"},1,"up","no"]
["ENSG00000197782","ZNF780A","ENST00000340963;ENST00000601715;ENST00000450241;ENST00000595687;ENST00000601688;ENST00000414720;ENST00000599368;ENST00000455521;ENST00000594395;ENST00000599972;ENST00000595773","GO:0003676(nucleic acid binding);GO:0046872(metal ion binding);GO:0006355(regulation of transcription, DNA-templated);GO:0005622(intracellular);GO:0005634(nucleus);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding)","NA","NA","NA","zinc finger protein 780A [Source:HGNC Symbol;Acc:HGNC:27603]",{"v":0.447875374686402,"d":"0.45"},{"v":0.288274716758655,"d":"0.29"},{"v":1.55364084551808,"d":"1.55"},{"v":0.635653035099764,"d":"0.64"},{"v":0.317172881120048,"d":"0.32"},1,"up","no"]
["MSTRG.6291","SMYD4","ENST00000305513;ENST00000491788;ENST00000573937;ENST00000476292;ENST00000576633","GO:0046872(metal ion binding);GO:0008168(methyltransferase activity);GO:0016740(transferase activity);GO:0032259(methylation);GO:0032259(methylation)","NA","NA","NA","SET and MYND domain containing 4 [Source:HGNC Symbol;Acc:HGNC:21067]",{"v":1.7314464828095,"d":"1.73"},{"v":1.11536536240224,"d":"1.12"},{"v":1.55235812512625,"d":"1.55"},{"v":0.634461422049766,"d":"0.63"},{"v":0.319149394625162,"d":"0.32"},1,"up","no"]
["MSTRG.11505","LYAR","ENST00000343470;MSTRG.11505.1;ENST00000502917;ENST00000513174","GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0005730(nucleolus);GO:0005515(protein binding);GO:0005515(protein binding)","NA","NA","NA","Ly1 antibody reactive [Source:HGNC Symbol;Acc:HGNC:26021]",{"v":7.32127604495268,"d":"7.32"},{"v":4.72909745899054,"d":"4.73"},{"v":1.54813388991046,"d":"1.55"},{"v":0.630530247940209,"d":"0.63"},{"v":0.321180806561001,"d":"0.32"},1,"up","no"]
["ENSG00000165410","CFL2","ENST00000298159;ENST00000554470;ENST00000556161;ENST00000341223;ENST00000555765;ENST00000422678","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0003779(actin binding);GO:0005622(intracellular);GO:0015629(actin cytoskeleton);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0005615(extracellular space);GO:0051015(actin filament binding);GO:0070062(extracellular exosome);GO:0031674(I band);GO:0030042(actin filament depolymerization);GO:0016363(nuclear matrix);GO:0030018(Z disc);GO:0030836(positive regulation of actin filament depolymerization);GO:0007015(actin filament organization);GO:0007519(skeletal muscle tissue development);GO:0030043(actin filament fragmentation);GO:0045214(sarcomere organization);GO:0046716(muscle cell cellular homeostasis);GO:0046716(muscle cell cellular homeostasis)","04810(Regulation of actin cytoskeleton);04666(Fc gamma R-mediated phagocytosis);04360(Axon guidance);05133(Pertussis);05133(Pertussis)","K05765","NA","cofilin 2 [Source:HGNC Symbol;Acc:HGNC:1875]",{"v":0.182624120490319,"d":"0.18"},{"v":0.308835719738125,"d":"0.31"},{"v":0.591330953055475,"d":"0.59"},{"v":-0.757962298334672,"d":"-0.76"},{"v":0.321593322471518,"d":"0.32"},1,"down","no"]
["ENSG00000186642","PDE2A","ENST00000541998;ENST00000441209;ENST00000485058;ENST00000420501;ENST00000444035;ENST00000334456;ENST00000537631;ENST00000544239","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0016787(hydrolase activity);GO:0005743(mitochondrial inner membrane);GO:0007165(signal transduction);GO:0005794(Golgi apparatus);GO:0005829(cytosol);GO:0005783(endoplasmic reticulum);GO:0005739(mitochondrion);GO:0042803(protein homodimerization activity);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0008152(metabolic process);GO:0030552(cAMP binding);GO:0048471(perinuclear region of cytoplasm);GO:0005741(mitochondrial outer membrane);GO:0005759(mitochondrial matrix);GO:0070588(calcium ion transmembrane transport);GO:0008081(phosphoric diester hydrolase activity);GO:0005262(calcium channel activity);GO:0004114(3',5'-cyclic-nucleotide phosphodiesterase activity);GO:0030553(cGMP binding);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0071260(cellular response to mechanical stimulus);GO:0030818(negative regulation of cAMP biosynthetic process);GO:0004112(cyclic-nucleotide phosphodiesterase activity);GO:0004115(3',5'-cyclic-AMP phosphodiesterase activity);GO:0004118(cGMP-stimulated cyclic-nucleotide phosphodiesterase activity);GO:0008144(drug binding);GO:0030911(TPR domain binding);GO:0047555(3',5'-cyclic-GMP phosphodiesterase activity);GO:0006198(cAMP catabolic process);GO:0006626(protein targeting to mitochondrion);GO:0019933(cAMP-mediated signaling);GO:0019934(cGMP-mediated signaling);GO:0033159(negative regulation of protein import into nucleus, translocation);GO:0035690(cellular response to drug);GO:0036006(cellular response to macrophage colony-stimulating factor stimulus);GO:0043116(negative regulation of vascular permeability);GO:0043117(positive regulation of vascular permeability);GO:0046069(cGMP catabolic process);GO:0050729(positive regulation of inflammatory response);GO:0061028(establishment of endothelial barrier);GO:0071321(cellular response to cGMP);GO:0071560(cellular response to transforming growth factor beta stimulus);GO:0042734(presynaptic membrane);GO:0042734(presynaptic membrane)","00230(Purine metabolism);04022(cGMP - PKG signaling pathway);04925(Aldosterone synthesis and secretion);04740(Olfactory transduction);05032(Morphine addiction);05032(Morphine addiction)","K18283","EC:3.1.4.17","phosphodiesterase 2A [Source:HGNC Symbol;Acc:HGNC:8777]",{"v":0.120152813840156,"d":"0.12"},{"v":0.20256716095795,"d":"0.20"},{"v":0.593150505106294,"d":"0.59"},{"v":-0.753529876421895,"d":"-0.75"},{"v":0.323305336424895,"d":"0.32"},1,"down","no"]
["MSTRG.834","CD58","ENST00000369489;ENST00000457047;MSTRG.834.1;ENST00000464088;ENST00000369487","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005886(plasma membrane);GO:0031225(anchored component of membrane);GO:0050900(leukocyte migration);GO:0005887(integral component of plasma membrane);GO:0005515(protein binding);GO:0070062(extracellular exosome);GO:0071346(cellular response to interferon-gamma);GO:0071356(cellular response to tumor necrosis factor);GO:0005102(receptor binding);GO:0043312(neutrophil degranulation);GO:2000484(positive regulation of interleukin-8 secretion);GO:0007155(cell adhesion);GO:0009986(cell surface);GO:0030667(secretory granule membrane);GO:0016337(single organismal cell-cell adhesion);GO:0101003(ficolin-1-rich granule membrane);GO:0034113(heterotypic cell-cell adhesion);GO:0034113(heterotypic cell-cell adhesion)","04514(Cell adhesion molecules (CAMs));05169(Epstein-Barr virus infection);05169(Epstein-Barr virus infection)","K06492","NA","CD58 molecule [Source:HGNC Symbol;Acc:HGNC:1688]",{"v":2.47119500884956,"d":"2.47"},{"v":3.96891430088496,"d":"3.97"},{"v":0.622637532964254,"d":"0.62"},{"v":-0.683535548935857,"d":"-0.68"},{"v":0.323935265795035,"d":"0.32"},1,"down","no"]
["ENSG00000113658","SMAD5","ENST00000545279;ENST00000545620;ENST00000509297;ENST00000507245;ENST00000511116;ENST00000507118;ENST00000507637","GO:0005737(cytoplasm);GO:0005634(nucleus);GO:0030509(BMP signaling pathway);GO:0016021(integral component of membrane);GO:0046872(metal ion binding);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0005622(intracellular);GO:0007165(signal transduction);GO:0007179(transforming growth factor beta receptor signaling pathway);GO:0005667(transcription factor complex);GO:0045893(positive regulation of transcription, DNA-templated);GO:0005515(protein binding);GO:0043234(protein complex);GO:0031625(ubiquitin protein ligase binding);GO:0030618(transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity);GO:0060395(SMAD protein signal transduction);GO:1901522(positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus);GO:0071141(SMAD protein complex);GO:0005057(signal transducer activity, downstream of receptor);GO:0009880(embryonic pattern specification);GO:0017151(DEAD/H-box RNA helicase binding);GO:0000977(RNA polymerase II regulatory region sequence-specific DNA binding);GO:0000979(RNA polymerase II core promoter sequence-specific DNA binding);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0001503(ossification);GO:0001657(ureteric bud development);GO:0001880(Mullerian duct regression);GO:0002051(osteoblast fate commitment);GO:0006468(protein phosphorylation);GO:0007281(germ cell development);GO:0030218(erythrocyte differentiation);GO:0045669(positive regulation of osteoblast differentiation);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0051216(cartilage development);GO:0060048(cardiac muscle contraction);GO:0060348(bone development);GO:0071407(cellular response to organic cyclic compound);GO:0071773(cellular response to BMP stimulus);GO:0071773(cellular response to BMP stimulus)","04350(TGF-beta signaling pathway);04550(Signaling pathways regulating pluripotency of stem cells);04550(Signaling pathways regulating pluripotency of stem cells)","K16790","NA","SMAD family member 5 [Source:HGNC Symbol;Acc:HGNC:6771]",{"v":0.514525368265178,"d":"0.51"},{"v":0.822076837339105,"d":"0.82"},{"v":0.625884765140193,"d":"0.63"},{"v":-0.676031035276273,"d":"-0.68"},{"v":0.324784096790254,"d":"0.32"},1,"down","no"]
["MSTRG.7787","PPAN;PPAN-P2RY11;P2RY11","ENST00000393793;MSTRG.7787.2;ENST00000486482;ENST00000446223;ENST00000471843;ENST00000466025;ENST00000253107;ENST00000321826;ENST00000444703;ENST00000393796;ENST00000468881","GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005730(nucleolus);GO:0019843(rRNA binding);GO:0000027(ribosomal large subunit assembly);GO:0030687(preribosome, large subunit precursor);GO:0005622(intracellular);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0004930(G-protein coupled receptor activity);GO:0007186(G-protein coupled receptor signaling pathway);GO:0005886(plasma membrane);GO:0004871(signal transducer activity);GO:0007165(signal transduction);GO:0045028(G-protein coupled purinergic nucleotide receptor activity);GO:0035589(G-protein coupled purinergic nucleotide receptor signaling pathway);GO:0005887(integral component of plasma membrane);GO:0004872(receptor activity);GO:0006952(defense response);GO:0019722(calcium-mediated signaling);GO:0007190(activation of adenylate cyclase activity);GO:0007200(phospholipase C-activating G-protein coupled receptor signaling pathway);GO:0045031(ATP-activated adenosine receptor activity);GO:0023041(neuronal signal transduction);GO:0030594(neurotransmitter receptor activity);GO:0001973(adenosine receptor signaling pathway);GO:0071318(cellular response to ATP);GO:0030687(preribosome, large subunit precursor)","04080(Neuroactive ligand-receptor interaction);04080(Neuroactive ligand-receptor interaction)","K08387","NA","peter pan homolog (Drosophila) [Source:HGNC Symbol;Acc:HGNC:9227];purinergic receptor P2Y11 [Source:HGNC Symbol;Acc:HGNC:8540];PPAN-P2RY11 readthrough [Source:HGNC Symbol;Acc:HGNC:33526]",{"v":8.19259703981312,"d":"8.19"},{"v":5.328603824091,"d":"5.33"},{"v":1.53747535194375,"d":"1.54"},{"v":0.620563282052817,"d":"0.62"},{"v":0.326056781453301,"d":"0.33"},1,"up","no"]
["MSTRG.182","FLJ37453","ENST00000317122","NA","NA","NA","NA","uncharacterized LOC729614 [Source:NCBI gene;Acc:729614]",{"v":0.384878,"d":"0.38"},{"v":0.632218,"d":"0.63"},{"v":0.608774188650118,"d":"0.61"},{"v":-0.716020903417596,"d":"-0.72"},{"v":0.326565649850752,"d":"0.33"},1,"down","no"]
["MSTRG.14522","MED30","ENST00000297347;ENST00000522839;ENST00000519391;ENST00000519879","GO:0005634(nucleus);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0005515(protein binding);GO:0030374(ligand-dependent nuclear receptor transcription coactivator activity);GO:0045893(positive regulation of transcription, DNA-templated);GO:0006367(transcription initiation from RNA polymerase II promoter);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0005654(nucleoplasm);GO:0004872(receptor activity);GO:0003712(transcription cofactor activity);GO:0030518(intracellular steroid hormone receptor signaling pathway);GO:0030521(androgen receptor signaling pathway);GO:0001104(RNA polymerase II transcription cofactor activity);GO:0042809(vitamin D receptor binding);GO:0016592(mediator complex);GO:0046966(thyroid hormone receptor binding);GO:0061630(ubiquitin protein ligase activity);GO:0016567(protein ubiquitination);GO:0019827(stem cell population maintenance);GO:0000151(ubiquitin ligase complex);GO:0000151(ubiquitin ligase complex)","04919(Thyroid hormone signaling pathway);04919(Thyroid hormone signaling pathway)","K15143","NA","mediator complex subunit 30 [Source:HGNC Symbol;Acc:HGNC:23032]",{"v":2.88898513472222,"d":"2.89"},{"v":4.62755943611111,"d":"4.63"},{"v":0.624299952190361,"d":"0.62"},{"v":-0.679688739576271,"d":"-0.68"},{"v":0.327940857648137,"d":"0.33"},1,"down","no"]
["MSTRG.10846","LINC02158","ENST00000432377","NA","NA","NA","NA","long intergenic non-protein coding RNA 2158 [Source:HGNC Symbol;Acc:HGNC:53019]",{"v":1.347226,"d":"1.35"},{"v":2.207781,"d":"2.21"},{"v":0.610217227161571,"d":"0.61"},{"v":-0.712605185390752,"d":"-0.71"},{"v":0.329012858527485,"d":"0.33"},1,"down","no"]
["MSTRG.14945","NDUFA8","ENST00000373768","GO:0016020(membrane);GO:0055114(oxidation-reduction process);GO:0005739(mitochondrion);GO:0005743(mitochondrial inner membrane);GO:0005747(mitochondrial respiratory chain complex I);GO:0006120(mitochondrial electron transport, NADH to ubiquinone);GO:0070469(respiratory chain);GO:0005758(mitochondrial intermembrane space);GO:0032981(mitochondrial respiratory chain complex I assembly);GO:0008137(NADH dehydrogenase (ubiquinone) activity);GO:0032403(protein complex binding)","00190(Oxidative phosphorylation);04723(Retrograde endocannabinoid signaling);05010(Alzheimer's disease);05012(Parkinson's disease);05016(Huntington's disease);04932(Non-alcoholic fatty liver disease (NAFLD))","K03952","NA","NADH:ubiquinone oxidoreductase subunit A8 [Source:HGNC Symbol;Acc:HGNC:7692]",{"v":6.849352,"d":"6.85"},{"v":4.437696,"d":"4.44"},{"v":1.54344777109563,"d":"1.54"},{"v":0.626156664257732,"d":"0.63"},{"v":0.330231345346819,"d":"0.33"},1,"up","no"]
["ENSG00000237440","ZNF737","ENST00000427401;ENST00000594419;ENST00000596797;ENST00000596530","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0005622(intracellular);GO:0005622(intracellular)","NA","NA","NA","zinc finger protein 737 [Source:HGNC Symbol;Acc:HGNC:32468]",{"v":1.28301792398983,"d":"1.28"},{"v":2.04511487115004,"d":"2.05"},{"v":0.627357388129667,"d":"0.63"},{"v":-0.672640554264619,"d":"-0.67"},{"v":0.331413980984041,"d":"0.33"},1,"down","no"]
["ENSG00000111850","SMIM8","ENST00000229570;ENST00000608353;ENST00000608535;ENST00000608868;ENST00000448282;ENST00000369570","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016021(integral component of membrane)","NA","NA","NA","small integral membrane protein 8 [Source:HGNC Symbol;Acc:HGNC:21401]",{"v":0.290665263115785,"d":"0.29"},{"v":0.186431186992799,"d":"0.19"},{"v":1.55910214274939,"d":"1.56"},{"v":0.640715447606458,"d":"0.64"},{"v":0.333454442751216,"d":"0.33"},1,"up","no"]
["MSTRG.2863","AP005018.2","ENST00000528464","NA","NA","NA","NA",null,{"v":4.616276,"d":"4.62"},{"v":2.994612,"d":"2.99"},{"v":1.54152724960696,"d":"1.54"},{"v":0.624360392218594,"d":"0.62"},{"v":0.335375074503549,"d":"0.34"},1,"up","no"]
["MSTRG.10538","NDUFA6","ENST00000617763;ENST00000498737;ENST00000602404;ENST00000470753","GO:0016020(membrane);GO:0055114(oxidation-reduction process);GO:0005743(mitochondrial inner membrane);GO:0005739(mitochondrion);GO:0070469(respiratory chain);GO:0031966(mitochondrial membrane);GO:0008137(NADH dehydrogenase (ubiquinone) activity);GO:0006120(mitochondrial electron transport, NADH to ubiquinone);GO:0006979(response to oxidative stress);GO:0032981(mitochondrial respiratory chain complex I assembly);GO:0005747(mitochondrial respiratory chain complex I);GO:0005747(mitochondrial respiratory chain complex I)","00190(Oxidative phosphorylation);04723(Retrograde endocannabinoid signaling);05010(Alzheimer's disease);05012(Parkinson's disease);05016(Huntington's disease);04932(Non-alcoholic fatty liver disease (NAFLD));04932(Non-alcoholic fatty liver disease (NAFLD))","K03950","NA","NADH:ubiquinone oxidoreductase subunit A6 [Source:HGNC Symbol;Acc:HGNC:7690]",{"v":7.34284266737288,"d":"7.34"},{"v":11.6289174618644,"d":"11.63"},{"v":0.631429597075809,"d":"0.63"},{"v":-0.663306209032555,"d":"-0.66"},{"v":0.33707439301286,"d":"0.34"},1,"down","no"]
["MSTRG.2002","FAM45A","ENST00000361432;ENST00000462327;ENST00000472379;ENST00000487888;ENST00000493766;ENST00000497903;ENST00000498549;ENST00000489988;ENST00000448258;ENST00000489936","NA","NA","NA","NA","family with sequence similarity 45 member A [Source:HGNC Symbol;Acc:HGNC:31793]",{"v":2.19694384288265,"d":"2.20"},{"v":3.4654429081318,"d":"3.47"},{"v":0.63395759247034,"d":"0.63"},{"v":-0.657541757959581,"d":"-0.66"},{"v":0.338951196429886,"d":"0.34"},1,"down","no"]
["MSTRG.10687","MRPS25","ENST00000496484;ENST00000253686;ENST00000447299;ENST00000444840;ENST00000474866","GO:0005739(mitochondrion);GO:0030529(intracellular ribonucleoprotein complex);GO:0005840(ribosome);GO:0003735(structural constituent of ribosome);GO:0005743(mitochondrial inner membrane);GO:0070125(mitochondrial translational elongation);GO:0070126(mitochondrial translational termination);GO:0070126(mitochondrial translational termination)","NA","NA","NA","mitochondrial ribosomal protein S25 [Source:HGNC Symbol;Acc:HGNC:14511]",{"v":2.19522449043284,"d":"2.20"},{"v":1.43948898588148,"d":"1.44"},{"v":1.52500263076941,"d":"1.53"},{"v":0.608811731458935,"d":"0.61"},{"v":0.339263091954522,"d":"0.34"},1,"up","no"]
["ENSG00000115526","CHST10","ENST00000264249;ENST00000487860;ENST00000418201;ENST00000484382;ENST00000485085","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016740(transferase activity);GO:0005794(Golgi apparatus);GO:0000139(Golgi membrane);GO:0008146(sulfotransferase activity);GO:0005975(carbohydrate metabolic process);GO:0016051(carbohydrate biosynthetic process);GO:0007155(cell adhesion);GO:0016232(HNK-1 sulfotransferase activity);GO:0016232(HNK-1 sulfotransferase activity)","00515(Mannose type O-glycan biosyntheis);00515(Mannose type O-glycan biosyntheis)","K09674","EC:2.8.2.-","carbohydrate sulfotransferase 10 [Source:HGNC Symbol;Acc:HGNC:19650]",{"v":0.322097978159126,"d":"0.32"},{"v":0.208022015154892,"d":"0.21"},{"v":1.54838408770963,"d":"1.55"},{"v":0.630763386664092,"d":"0.63"},{"v":0.341685394987592,"d":"0.34"},1,"up","no"]
["ENSG00000135974","C2orf49","ENST00000410049;ENST00000258457","GO:0003674(molecular_function);GO:0008150(biological_process);GO:0005654(nucleoplasm);GO:0048598(embryonic morphogenesis);GO:0072669(tRNA-splicing ligase complex);GO:0006388(tRNA splicing, via endonucleolytic cleavage and ligation);GO:0006388(tRNA splicing, via endonucleolytic cleavage and ligation)","NA","NA","NA","chromosome 2 open reading frame 49 [Source:HGNC Symbol;Acc:HGNC:28772]",{"v":1.37373317533557,"d":"1.37"},{"v":2.16037655704698,"d":"2.16"},{"v":0.635876727533707,"d":"0.64"},{"v":-0.653180986316972,"d":"-0.65"},{"v":0.343216452344732,"d":"0.34"},1,"down","no"]
["MSTRG.15198","SH3KBP1","ENST00000397821;ENST00000379698;ENST00000494961;ENST00000431164;ENST00000379716;ENST00000379697;ENST00000432234;ENST00000477102","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0006915(apoptotic process);GO:0030054(cell junction);GO:0045202(synapse);GO:0030659(cytoplasmic vesicle membrane);GO:0031410(cytoplasmic vesicle);GO:0005925(focal adhesion);GO:0005886(plasma membrane);GO:0005829(cytosol);GO:0006897(endocytosis);GO:0061024(membrane organization);GO:0007010(cytoskeleton organization);GO:0017124(SH3 domain binding);GO:0008360(regulation of cell shape);GO:0043005(neuron projection);GO:0007411(axon guidance);GO:0016477(cell migration);GO:0007267(cell-cell signaling);GO:0042059(negative regulation of epidermal growth factor receptor signaling pathway);GO:0030139(endocytic vesicle);GO:0005911(cell-cell junction);GO:0005911(cell-cell junction)","04144(Endocytosis);04144(Endocytosis)","K12470","NA","SH3 domain containing kinase binding protein 1 [Source:HGNC Symbol;Acc:HGNC:13867]",{"v":19.2239246982699,"d":"19.22"},{"v":30.1086713039792,"d":"30.11"},{"v":0.638484657930729,"d":"0.64"},{"v":-0.647276140884468,"d":"-0.65"},{"v":0.344096952571173,"d":"0.34"},1,"down","no"]
["MSTRG.13800","C7orf43;MIR4658","ENST00000457641;ENST00000394035;ENST00000316937;ENST00000584344;ENST00000456769;ENST00000472061;ENST00000498638;ENST00000419841;ENST00000470260;ENST00000419037;ENST00000448720","GO:0043231(intracellular membrane-bounded organelle);GO:0005815(microtubule organizing center);GO:0005886(plasma membrane);GO:0005886(plasma membrane)","NA","NA","NA","chromosome 7 open reading frame 43 [Source:HGNC Symbol;Acc:HGNC:25604];microRNA 4658 [Source:HGNC Symbol;Acc:HGNC:41673]",{"v":8.36311067783191,"d":"8.36"},{"v":13.0957743169915,"d":"13.10"},{"v":0.638611392911754,"d":"0.64"},{"v":-0.646989803879336,"d":"-0.65"},{"v":0.346157980314933,"d":"0.35"},1,"down","no"]
["MSTRG.15042","FUBP3","ENST00000319725;ENST00000467100;ENST00000487406;ENST00000472006;ENST00000492199","GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0006366(transcription from RNA polymerase II promoter);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0045893(positive regulation of transcription, DNA-templated);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:0010628(positive regulation of gene expression);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0001077(transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0001077(transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding)","NA","NA","NA","far upstream element binding protein 3 [Source:HGNC Symbol;Acc:HGNC:4005]",{"v":4.31280110477574,"d":"4.31"},{"v":2.85234881913928,"d":"2.85"},{"v":1.51201742081362,"d":"1.51"},{"v":0.59647476176575,"d":"0.60"},{"v":0.346454389250692,"d":"0.35"},1,"up","no"]
["MSTRG.6170","AC092135.3","ENST00000624151","NA","NA","NA","NA",null,{"v":0.43062,"d":"0.43"},{"v":0.688025,"d":"0.69"},{"v":0.625878420115548,"d":"0.63"},{"v":-0.676045660943007,"d":"-0.68"},{"v":0.347622621283957,"d":"0.35"},1,"down","no"]
["ENSG00000103257","SLC7A5","ENST00000261622;ENST00000563489","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0043231(intracellular membrane-bounded organelle);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0015171(amino acid transmembrane transporter activity);GO:0003333(amino acid transmembrane transport);GO:0006810(transport);GO:0005737(cytoplasm);GO:0007275(multicellular organism development);GO:0007399(nervous system development);GO:0030154(cell differentiation);GO:0006865(amino acid transport);GO:0050900(leukocyte migration);GO:0005887(integral component of plasma membrane);GO:0070062(extracellular exosome);GO:0015297(antiporter activity);GO:0016324(apical plasma membrane);GO:0042605(peptide antigen binding);GO:0006520(cellular amino acid metabolic process);GO:0015179(L-amino acid transmembrane transporter activity);GO:0015804(neutral amino acid transport);GO:1902475(L-alpha-amino acid transmembrane transport);GO:0015175(neutral amino acid transmembrane transporter activity);GO:0015807(L-amino acid transport);GO:0015807(L-amino acid transport)","04150(mTOR signaling pathway);05230(Central carbon metabolism in cancer);05230(Central carbon metabolism in cancer)","K13780","NA","solute carrier family 7 member 5 [Source:HGNC Symbol;Acc:HGNC:11063]",{"v":3.41862725205479,"d":"3.42"},{"v":2.26725058630137,"d":"2.27"},{"v":1.5078294709504,"d":"1.51"},{"v":0.592473275207613,"d":"0.59"},{"v":0.348925128475695,"d":"0.35"},1,"up","no"]
["MSTRG.7401","ANKRD12;NDUFV2;AP005263.1","ENST00000400020;ENST00000262126;ENST00000546007;ENST00000318388;ENST00000581758;ENST00000577992;ENST00000474350;ENST00000465096;ENST00000483511;ENST00000540578;MSTRG.7401.13;MSTRG.7401.23;ENST00000497577;ENST00000577703;ENST00000581635;ENST00000400033;MSTRG.7401.15;ENST00000579126;ENST00000585234;ENST00000474740","GO:0005634(nucleus);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0016020(membrane);GO:0046872(metal ion binding);GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0005739(mitochondrion);GO:0005743(mitochondrial inner membrane);GO:0005515(protein binding);GO:0007399(nervous system development);GO:0070469(respiratory chain);GO:0051536(iron-sulfur cluster binding);GO:0051537(2 iron, 2 sulfur cluster binding);GO:0003954(NADH dehydrogenase activity);GO:0008137(NADH dehydrogenase (ubiquinone) activity);GO:0006120(mitochondrial electron transport, NADH to ubiquinone);GO:0032981(mitochondrial respiratory chain complex I assembly);GO:0005747(mitochondrial respiratory chain complex I);GO:0009055(electron carrier activity);GO:0048738(cardiac muscle tissue development);GO:0043209(myelin sheath);GO:0043209(myelin sheath)","00190(Oxidative phosphorylation);04723(Retrograde endocannabinoid signaling);05010(Alzheimer's disease);05012(Parkinson's disease);05016(Huntington's disease);04932(Non-alcoholic fatty liver disease (NAFLD));04932(Non-alcoholic fatty liver disease (NAFLD))","K03943","EC:1.6.5.3;EC:1.6.99.3","ankyrin repeat domain 12 [Source:HGNC Symbol;Acc:HGNC:29135];NADH:ubiquinone oxidoreductase core subunit V2 [Source:HGNC Symbol;Acc:HGNC:7717]",{"v":2.86239344929175,"d":"2.86"},{"v":4.46863479124825,"d":"4.47"},{"v":0.640552111105097,"d":"0.64"},{"v":-0.642612151370054,"d":"-0.64"},{"v":0.349057446765902,"d":"0.35"},1,"down","no"]
["MSTRG.12334","TGFBI","ENST00000507018;ENST00000442011;ENST00000504185;ENST00000514242;ENST00000515433;ENST00000504411;ENST00000508767;ENST00000513497;ENST00000506699;ENST00000509485;ENST00000509749;ENST00000514554;ENST00000604555","GO:0005615(extracellular space);GO:0007155(cell adhesion);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0005578(proteinaceous extracellular matrix);GO:0005518(collagen binding);GO:0050896(response to stimulus);GO:0005886(plasma membrane);GO:0008283(cell proliferation);GO:0005178(integrin binding);GO:0050840(extracellular matrix binding);GO:0002062(chondrocyte differentiation);GO:0030198(extracellular matrix organization);GO:0005604(basement membrane);GO:0070062(extracellular exosome);GO:0044267(cellular protein metabolic process);GO:0007601(visual perception);GO:0031012(extracellular matrix);GO:0001525(angiogenesis);GO:0005802(trans-Golgi network);GO:0007162(negative regulation of cell adhesion);GO:0007162(negative regulation of cell adhesion)","NA","NA","NA","transforming growth factor beta induced [Source:HGNC Symbol;Acc:HGNC:11771]",{"v":11.0154387258643,"d":"11.02"},{"v":17.1550300134443,"d":"17.16"},{"v":0.642111305968661,"d":"0.64"},{"v":-0.639104693722981,"d":"-0.64"},{"v":0.350748131014421,"d":"0.35"},1,"down","no"]
["MSTRG.14246","PPP2R2A","ENST00000380737;ENST00000519439;ENST00000518215;ENST00000522482;ENST00000521484;ENST00000518208;ENST00000524099;ENST00000640787;ENST00000520438;ENST00000517754;ENST00000523964;ENST00000523473;ENST00000523925;ENST00000518397;ENST00000518890;ENST00000520329;ENST00000524169","GO:0050790(regulation of catalytic activity);GO:0005515(protein binding);GO:0019888(protein phosphatase regulator activity);GO:0000159(protein phosphatase type 2A complex);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0000086(G2/M transition of mitotic cell cycle);GO:0004722(protein serine/threonine phosphatase activity);GO:0006470(protein dephosphorylation);GO:0000184(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay);GO:0007084(mitotic nuclear envelope reassembly);GO:0000278(mitotic cell cycle);GO:0032502(developmental process);GO:0070262(peptidyl-serine dephosphorylation);GO:0032403(protein complex binding);GO:0048156(tau protein binding);GO:0051721(protein phosphatase 2A binding);GO:0043278(response to morphine);GO:0043278(response to morphine)","03015(mRNA surveillance pathway);04390(Hippo signaling pathway);04071(Sphingolipid signaling pathway);04151(PI3K-Akt signaling pathway);04152(AMPK signaling pathway);04530(Tight junction);04261(Adrenergic signaling in cardiomyocytes);04728(Dopaminergic synapse);05160(Hepatitis C);05165(Human papillomavirus infection);05142(Chagas disease (American trypanosomiasis));05142(Chagas disease (American trypanosomiasis))","K04354","NA","protein phosphatase 2 regulatory subunit Balpha [Source:HGNC Symbol;Acc:HGNC:9304]",{"v":1.78550424297521,"d":"1.79"},{"v":2.78345493452003,"d":"2.78"},{"v":0.64147050517385,"d":"0.64"},{"v":-0.640545163193098,"d":"-0.64"},{"v":0.352432095641019,"d":"0.35"},1,"down","no"]
["MSTRG.3621","ELK3","ENST00000228741;ENST00000547249;ENST00000549529;ENST00000547860;ENST00000552142;ENST00000549985","GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0006355(regulation of transcription, DNA-templated);GO:0006366(transcription from RNA polymerase II promoter);GO:0006351(transcription, DNA-templated);GO:0005739(mitochondrion);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0043565(sequence-specific DNA binding);GO:0005515(protein binding);GO:0001525(angiogenesis);GO:0042060(wound healing);GO:0045892(negative regulation of transcription, DNA-templated);GO:0045893(positive regulation of transcription, DNA-templated);GO:0005737(cytoplasm);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0030154(cell differentiation);GO:0007165(signal transduction);GO:0001077(transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0003714(transcription corepressor activity);GO:0032422(purine-rich negative regulatory element binding);GO:0032422(purine-rich negative regulatory element binding)","NA","NA","NA","ELK3, ETS transcription factor [Source:HGNC Symbol;Acc:HGNC:3325]",{"v":11.1988920654045,"d":"11.20"},{"v":7.4715083341222,"d":"7.47"},{"v":1.49887968594767,"d":"1.50"},{"v":0.583884583784179,"d":"0.58"},{"v":0.354134882313014,"d":"0.35"},1,"up","no"]
["MSTRG.9041","BCL2L11","ENST00000393256;ENST00000622509;ENST00000405953;ENST00000615946;ENST00000619294;ENST00000452231;ENST00000357757;ENST00000308659;ENST00000621302;ENST00000622612;ENST00000620862;ENST00000337565;ENST00000433098;ENST00000393252;ENST00000361493;ENST00000431217;ENST00000432179","GO:0016020(membrane);GO:0005739(mitochondrion);GO:0005515(protein binding);GO:0006915(apoptotic process);GO:0005829(cytosol);GO:0008017(microtubule binding);GO:0012505(endomembrane system);GO:0043065(positive regulation of apoptotic process);GO:0032464(positive regulation of protein homooligomerization);GO:0090200(positive regulation of release of cytochrome c from mitochondria);GO:0005741(mitochondrial outer membrane);GO:0034976(response to endoplasmic reticulum stress);GO:1900740(positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway);GO:0001844(protein insertion into mitochondrial membrane involved in apoptotic signaling pathway);GO:0008630(intrinsic apoptotic signaling pathway in response to DNA damage);GO:1902237(positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway);GO:1903896(positive regulation of IRE1-mediated unfolded protein response);GO:2000271(positive regulation of fibroblast apoptotic process);GO:2001244(positive regulation of intrinsic apoptotic signaling pathway);GO:0046982(protein heterodimerization activity);GO:0070840(dynein complex binding);GO:0001701(in utero embryonic development);GO:0001776(leukocyte homeostasis);GO:0001782(B cell homeostasis);GO:0001783(B cell apoptotic process);GO:0001822(kidney development);GO:0002260(lymphocyte homeostasis);GO:0002262(myeloid cell homeostasis);GO:0007160(cell-matrix adhesion);GO:0007283(spermatogenesis);GO:0007420(brain development);GO:0008584(male gonad development);GO:0009791(post-embryonic development);GO:0010942(positive regulation of cell death);GO:0030879(mammary gland development);GO:0035148(tube formation);GO:0042475(odontogenesis of dentin-containing tooth);GO:0042981(regulation of apoptotic process);GO:0043029(T cell homeostasis);GO:0043280(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process);GO:0043525(positive regulation of neuron apoptotic process);GO:0043583(ear development);GO:0045787(positive regulation of cell cycle);GO:0046620(regulation of organ growth);GO:0048066(developmental pigmentation);GO:0048070(regulation of developmental pigmentation);GO:0048536(spleen development);GO:0048538(thymus development);GO:0048563(post-embryonic animal organ morphogenesis);GO:0060139(positive regulation of apoptotic process by virus);GO:0060154(cellular process regulating host cell cycle in response to virus);GO:0070242(thymocyte apoptotic process);GO:0097192(extrinsic apoptotic signaling pathway in absence of ligand);GO:1902110(positive regulation of mitochondrial membrane permeability involved in apoptotic process);GO:1902263(apoptotic process involved in embryonic digit morphogenesis);GO:0005737(cytoplasm);GO:0005868(cytoplasmic dynein complex);GO:0019898(extrinsic component of membrane);GO:0043231(intracellular membrane-bounded organelle);GO:0097136(Bcl-2 family protein complex);GO:0097136(Bcl-2 family protein complex)","04068(FoxO signaling pathway);04151(PI3K-Akt signaling pathway);04210(Apoptosis);04215(Apoptosis - multiple species);05200(Pathways in cancer);05206(MicroRNAs in cancer);05210(Colorectal cancer);04932(Non-alcoholic fatty liver disease (NAFLD));01521(EGFR tyrosine kinase inhibitor resistance);01521(EGFR tyrosine kinase inhibitor resistance)","K16341","NA","BCL2 like 11 [Source:HGNC Symbol;Acc:HGNC:994]",{"v":2.24540555271853,"d":"2.25"},{"v":3.48760765214779,"d":"3.49"},{"v":0.643824012524956,"d":"0.64"},{"v":-0.635261709273023,"d":"-0.64"},{"v":0.355371541458253,"d":"0.36"},1,"down","no"]
["ENSG00000110881","ASIC1","ENST00000228468;ENST00000453327;ENST00000548350;ENST00000552438;ENST00000550558;ENST00000549792","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005794(Golgi apparatus);GO:0005886(plasma membrane);GO:0006811(ion transport);GO:0005515(protein binding);GO:0006814(sodium ion transport);GO:0006816(calcium ion transport);GO:0005272(sodium channel activity);GO:0015280(ligand-gated sodium channel activity);GO:0005887(integral component of plasma membrane);GO:0034220(ion transmembrane transport);GO:0007165(signal transduction);GO:0035725(sodium ion transmembrane transport);GO:0070207(protein homotrimerization);GO:0005216(ion channel activity);GO:0005261(cation channel activity);GO:0022839(ion gated channel activity);GO:0044736(acid-sensing ion channel activity);GO:0006812(cation transport);GO:0007613(memory);GO:0008306(associative learning);GO:0009268(response to pH);GO:0010447(response to acidic pH);GO:0042391(regulation of membrane potential);GO:0046929(negative regulation of neurotransmitter secretion);GO:0050915(sensory perception of sour taste);GO:0070588(calcium ion transmembrane transport);GO:0071467(cellular response to pH);GO:0009986(cell surface);GO:0045202(synapse);GO:0045202(synapse)","04750(Inflammatory mediator regulation of TRP channels);04750(Inflammatory mediator regulation of TRP channels)","K04829","NA","acid sensing ion channel subunit 1 [Source:HGNC Symbol;Acc:HGNC:100]",{"v":0.485522388685814,"d":"0.49"},{"v":0.320554731940818,"d":"0.32"},{"v":1.51463179390986,"d":"1.51"},{"v":0.598967118012844,"d":"0.60"},{"v":0.356243832981229,"d":"0.36"},1,"up","no"]
["ENSG00000162063","CCNF","ENST00000397066;ENST00000564333;ENST00000564236","GO:0051726(regulation of cell cycle);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016567(protein ubiquitination);GO:0051301(cell division);GO:0005813(centrosome);GO:0030054(cell junction);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0007049(cell cycle);GO:0005829(cytosol);GO:0005814(centriole);GO:0000209(protein polyubiquitination);GO:0043687(post-translational protein modification);GO:0004842(ubiquitin-protein transferase activity);GO:0010826(negative regulation of centrosome duplication);GO:0019005(SCF ubiquitin ligase complex);GO:0000320(re-entry into mitotic cell cycle);GO:0001890(placenta development);GO:0031146(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process);GO:0031146(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)","NA","NA","NA","cyclin F [Source:HGNC Symbol;Acc:HGNC:1591]",{"v":0.614193448882549,"d":"0.61"},{"v":0.403881840386749,"d":"0.40"},{"v":1.52072558720246,"d":"1.52"},{"v":0.604759844252892,"d":"0.60"},{"v":0.357000677445948,"d":"0.36"},1,"up","no"]
["ENSG00000186575","NF2","ENST00000338641;ENST00000432151;ENST00000403999;ENST00000361452;ENST00000403435;ENST00000361166","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005829(cytosol);GO:0003779(actin binding);GO:0005886(plasma membrane);GO:0005856(cytoskeleton);GO:0042995(cell projection);GO:0005515(protein binding);GO:0008092(cytoskeletal protein binding);GO:0001707(mesoderm formation);GO:0006469(negative regulation of protein kinase activity);GO:0007398(ectoderm development);GO:0007420(brain development);GO:0008285(negative regulation of cell proliferation);GO:0014013(regulation of gliogenesis);GO:0021766(hippocampus development);GO:0031647(regulation of protein stability);GO:0042127(regulation of cell proliferation);GO:0042475(odontogenesis of dentin-containing tooth);GO:0043409(negative regulation of MAPK cascade);GO:0045216(cell-cell junction organization);GO:0045597(positive regulation of cell differentiation);GO:0050767(regulation of neurogenesis);GO:0070306(lens fiber cell differentiation);GO:0072091(regulation of stem cell proliferation);GO:1900180(regulation of protein localization to nucleus);GO:2000177(regulation of neural precursor cell proliferation);GO:0001726(ruffle);GO:0005912(adherens junction);GO:0030027(lamellipodium);GO:0030175(filopodium);GO:0030864(cortical actin cytoskeleton);GO:0032154(cleavage furrow);GO:0043005(neuron projection);GO:0044297(cell body);GO:0045177(apical part of cell);GO:0048471(perinuclear region of cytoplasm);GO:0032587(ruffle membrane);GO:0042981(regulation of apoptotic process);GO:0051726(regulation of cell cycle);GO:0046426(negative regulation of JAK-STAT cascade);GO:0005769(early endosome);GO:0031527(filopodium membrane);GO:0005730(nucleolus);GO:0030036(actin cytoskeleton organization);GO:0001953(negative regulation of cell-matrix adhesion);GO:0008156(negative regulation of DNA replication);GO:0014010(Schwann cell proliferation);GO:0022408(negative regulation of cell-cell adhesion);GO:0030336(negative regulation of cell migration);GO:0035330(regulation of hippo signaling);GO:0042532(negative regulation of tyrosine phosphorylation of STAT protein);GO:0051496(positive regulation of stress fiber assembly);GO:0051496(positive regulation of stress fiber assembly)","04390(Hippo signaling pathway);04392(Hippo signaling pathway - multiple species);04530(Tight junction);04530(Tight junction)","K16684","NA","neurofibromin 2 [Source:HGNC Symbol;Acc:HGNC:7773]",{"v":3.23495069288703,"d":"3.23"},{"v":2.16474255034868,"d":"2.16"},{"v":1.49438125673003,"d":"1.49"},{"v":0.579548265277842,"d":"0.58"},{"v":0.358013094181685,"d":"0.36"},1,"up","no"]
["ENSG00000104783","KCNN4","ENST00000262888;ENST00000600909;ENST00000597184;ENST00000601549","GO:0016021(integral component of membrane);GO:0006813(potassium ion transport);GO:0071805(potassium ion transmembrane transport);GO:0016286(small conductance calcium-activated potassium channel activity);GO:0006810(transport);GO:0016020(membrane);GO:0006811(ion transport);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0002376(immune system process);GO:0005516(calmodulin binding);GO:0015269(calcium-activated potassium channel activity);GO:0005267(potassium channel activity);GO:0008076(voltage-gated potassium channel complex);GO:0006952(defense response);GO:0019903(protein phosphatase binding);GO:0006816(calcium ion transport);GO:0006884(cell volume homeostasis);GO:0030322(stabilization of membrane potential);GO:0045332(phospholipid translocation);GO:0046541(saliva secretion);GO:0050714(positive regulation of protein secretion);GO:0050862(positive regulation of T cell receptor signaling pathway);GO:0031982(vesicle);GO:0043025(neuronal cell body);GO:0043025(neuronal cell body)","04911(Insulin secretion);04970(Salivary secretion);04974(Protein digestion and absorption);04974(Protein digestion and absorption)","K04945","NA","potassium calcium-activated channel subfamily N member 4 [Source:HGNC Symbol;Acc:HGNC:6293]",{"v":1.90429432198237,"d":"1.90"},{"v":1.27146096442688,"d":"1.27"},{"v":1.4977214206814,"d":"1.50"},{"v":0.582769304453068,"d":"0.58"},{"v":0.359478185393854,"d":"0.36"},1,"up","no"]
["ENSG00000095002","MSH2","ENST00000406134;ENST00000467323;ENST00000233146;ENST00000461394","GO:0005634(nucleus);GO:0016020(membrane);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0006281(DNA repair);GO:0006974(cellular response to DNA damage stimulus);GO:0030983(mismatched DNA binding);GO:0006298(mismatch repair);GO:0032301(MutSalpha complex);GO:0005654(nucleoplasm);GO:0019901(protein kinase binding);GO:0006302(double-strand break repair);GO:0031573(intra-S DNA damage checkpoint);GO:0000784(nuclear chromosome, telomeric region);GO:0008022(protein C-terminus binding);GO:0032300(mismatch repair complex);GO:0019899(enzyme binding);GO:0010165(response to X-ray);GO:0008094(DNA-dependent ATPase activity);GO:0043524(negative regulation of neuron apoptotic process);GO:0030183(B cell differentiation);GO:0042803(protein homodimerization activity);GO:0003697(single-stranded DNA binding);GO:0032405(MutLalpha complex binding);GO:0016887(ATPase activity);GO:0008584(male gonad development);GO:0032139(dinucleotide insertion or deletion binding);GO:0032142(single guanine insertion binding);GO:0032181(dinucleotide repeat insertion binding);GO:0000403(Y-form DNA binding);GO:0000404(heteroduplex DNA loop binding);GO:0000406(double-strand/single-strand DNA junction binding);GO:0043570(maintenance of DNA repeat elements);GO:0045910(negative regulation of DNA recombination);GO:0051096(positive regulation of helicase activity);GO:0032302(MutSbeta complex);GO:0000287(magnesium ion binding);GO:0016446(somatic hypermutation of immunoglobulin genes);GO:0000400(four-way junction DNA binding);GO:0003690(double-stranded DNA binding);GO:0032137(guanine/thymine mispair binding);GO:0032143(single thymine insertion binding);GO:0032357(oxidized purine DNA binding);GO:0043531(ADP binding);GO:0003684(damaged DNA binding);GO:0019237(centromeric DNA binding);GO:0001701(in utero embryonic development);GO:0002204(somatic recombination of immunoglobulin genes involved in immune response);GO:0006119(oxidative phosphorylation);GO:0006301(postreplication repair);GO:0006311(meiotic gene conversion);GO:0007050(cell cycle arrest);GO:0007281(germ cell development);GO:0008340(determination of adult lifespan);GO:0008630(intrinsic apoptotic signaling pathway in response to DNA damage);GO:0010224(response to UV-B);GO:0016447(somatic recombination of immunoglobulin gene segments);GO:0019724(B cell mediated immunity);GO:0042771(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator);GO:0045128(negative regulation of reciprocal meiotic recombination);GO:0045190(isotype switching);GO:0048298(positive regulation of isotype switching to IgA isotypes);GO:0048304(positive regulation of isotype switching to IgG isotypes);GO:0048304(positive regulation of isotype switching to IgG isotypes)","03430(Mismatch repair);05200(Pathways in cancer);05210(Colorectal cancer);01524(Platinum drug resistance);01524(Platinum drug resistance)","K08735","NA","mutS homolog 2 [Source:HGNC Symbol;Acc:HGNC:7325]",{"v":1.7284310766696,"d":"1.73"},{"v":1.1543779340949,"d":"1.15"},{"v":1.49728353740995,"d":"1.50"},{"v":0.582347447369322,"d":"0.58"},{"v":0.360272672413642,"d":"0.36"},1,"up","no"]
["ENSG00000168393","DTYMK","ENST00000305784;ENST00000464603;ENST00000400770;ENST00000420144;ENST00000432348","GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0005737(cytoplasm);GO:0046939(nucleotide phosphorylation);GO:0005829(cytosol);GO:0004798(thymidylate kinase activity);GO:0006233(dTDP biosynthetic process);GO:0008283(cell proliferation);GO:0015949(nucleobase-containing small molecule interconversion);GO:0009165(nucleotide biosynthetic process);GO:0007049(cell cycle);GO:0006235(dTTP biosynthetic process);GO:0009041(uridylate kinase activity);GO:0050145(nucleoside phosphate kinase activity);GO:0006227(dUDP biosynthetic process);GO:0043627(response to estrogen);GO:0045445(myoblast differentiation);GO:0046686(response to cadmium ion);GO:0046940(nucleoside monophosphate phosphorylation);GO:0071363(cellular response to growth factor stimulus);GO:0005739(mitochondrion);GO:0005758(mitochondrial intermembrane space);GO:0005759(mitochondrial matrix);GO:0005759(mitochondrial matrix)","00240(Pyrimidine metabolism);00240(Pyrimidine metabolism)","K00943","EC:2.7.4.9","deoxythymidylate kinase [Source:HGNC Symbol;Acc:HGNC:3061]",{"v":0.922886807833537,"d":"0.92"},{"v":0.609430641778866,"d":"0.61"},{"v":1.51434264141974,"d":"1.51"},{"v":0.5986916723967,"d":"0.60"},{"v":0.361459838585037,"d":"0.36"},1,"up","no"]
["MSTRG.9806","STAU1","ENST00000371856;ENST00000360426;ENST00000340954;ENST00000371828;ENST00000456866;ENST00000347458;ENST00000371792;ENST00000371802;ENST00000614381;ENST00000437404","GO:0003723(RNA binding);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005829(cytosol);GO:0005783(endoplasmic reticulum);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0070062(extracellular exosome);GO:0005875(microtubule associated complex);GO:0045070(positive regulation of viral genome replication);GO:0036464(cytoplasmic ribonucleoprotein granule);GO:0005791(rough endoplasmic reticulum);GO:0003725(double-stranded RNA binding);GO:0008157(protein phosphatase 1 binding);GO:0034599(cellular response to oxidative stress);GO:0046726(positive regulation by virus of viral protein levels in host cell);GO:1900273(positive regulation of long-term synaptic potentiation);GO:0010494(cytoplasmic stress granule);GO:0030425(dendrite);GO:0043005(neuron projection);GO:0043025(neuronal cell body);GO:0044297(cell body);GO:0044297(cell body)","NA","NA","NA","staufen double-stranded RNA binding protein 1 [Source:HGNC Symbol;Acc:HGNC:11370]",{"v":5.96091717489008,"d":"5.96"},{"v":9.20139189692232,"d":"9.20"},{"v":0.647827767979743,"d":"0.65"},{"v":-0.626317786883789,"d":"-0.63"},{"v":0.362215048412574,"d":"0.36"},1,"down","no"]
["MSTRG.1528","FBXO18","ENST00000362091;ENST00000470353;ENST00000379999;ENST00000489042;ENST00000479433;ENST00000460453;ENST00000461504;ENST00000462507;ENST00000397269;ENST00000475867;ENST00000496013;ENST00000494526;ENST00000485290;ENST00000470089;ENST00000469009","GO:0005634(nucleus);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0016787(hydrolase activity);GO:0016567(protein ubiquitination);GO:0003677(DNA binding);GO:0004003(ATP-dependent DNA helicase activity);GO:0004386(helicase activity);GO:0032508(DNA duplex unwinding);GO:0005694(chromosome);GO:0005515(protein binding);GO:0006281(DNA repair);GO:0006974(cellular response to DNA damage stimulus);GO:0003690(double-stranded DNA binding);GO:0031297(replication fork processing);GO:0000785(chromatin);GO:0000724(double-strand break repair via homologous recombination);GO:0008219(cell death);GO:0003697(single-stranded DNA binding);GO:2000042(negative regulation of double-strand break repair via homologous recombination);GO:0003678(DNA helicase activity);GO:0001934(positive regulation of protein phosphorylation);GO:0043138(3'-5' DNA helicase activity);GO:0019005(SCF ubiquitin ligase complex);GO:0048478(replication fork protection);GO:0072429(response to intra-S DNA damage checkpoint signaling);GO:0015616(DNA translocase activity);GO:0000737(DNA catabolic process, endonucleolytic);GO:1902231(positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage);GO:0035562(negative regulation of chromatin binding);GO:0035562(negative regulation of chromatin binding)","NA","NA","NA","F-box protein, helicase, 18 [Source:HGNC Symbol;Acc:HGNC:13620]",{"v":6.52678284346914,"d":"6.53"},{"v":4.39560977351708,"d":"4.40"},{"v":1.48484128022284,"d":"1.48"},{"v":0.570308724646637,"d":"0.57"},{"v":0.363028862348807,"d":"0.36"},1,"up","no"]
["ENSG00000239779","WBP1","ENST00000233615;ENST00000490120;ENST00000473467;ENST00000409737;ENST00000464774;ENST00000393972;ENST00000494741;ENST00000428943;ENST00000466303;ENST00000492047;ENST00000484744;ENST00000470536","GO:0005515(protein binding);GO:0008150(biological_process);GO:0005575(cellular_component);GO:0050699(WW domain binding);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016021(integral component of membrane)","NA","NA","NA","WW domain binding protein 1 [Source:HGNC Symbol;Acc:HGNC:12737]",{"v":6.50619189704676,"d":"6.51"},{"v":4.3796823490566,"d":"4.38"},{"v":1.48553967582791,"d":"1.49"},{"v":0.570987137220299,"d":"0.57"},{"v":0.36538090571916,"d":"0.37"},1,"up","no"]
["MSTRG.3659","CHST11","ENST00000549260;ENST00000303694;ENST00000549016;ENST00000547956;ENST00000550711","GO:0016021(integral component of membrane);GO:0016740(transferase activity);GO:0005794(Golgi apparatus);GO:0000139(Golgi membrane);GO:0008146(sulfotransferase activity);GO:0005975(carbohydrate metabolic process);GO:0016051(carbohydrate biosynthetic process);GO:0016020(membrane);GO:0030206(chondroitin sulfate biosynthetic process);GO:0001537(N-acetylgalactosamine 4-O-sulfotransferase activity);GO:0047756(chondroitin 4-sulfotransferase activity);GO:0050659(N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase activity);GO:0002063(chondrocyte development);GO:0007585(respiratory gaseous exchange);GO:0009791(post-embryonic development);GO:0030204(chondroitin sulfate metabolic process);GO:0030326(embryonic limb morphogenesis);GO:0030512(negative regulation of transforming growth factor beta receptor signaling pathway);GO:0033037(polysaccharide localization);GO:0036342(post-anal tail morphogenesis);GO:0042127(regulation of cell proliferation);GO:0042733(embryonic digit morphogenesis);GO:0043066(negative regulation of apoptotic process);GO:0048589(developmental growth);GO:0048703(embryonic viscerocranium morphogenesis);GO:0048704(embryonic skeletal system morphogenesis);GO:0051216(cartilage development);GO:0051216(cartilage development)","00532(Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate);00532(Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate)","K01017","EC:2.8.2.5","carbohydrate sulfotransferase 11 [Source:HGNC Symbol;Acc:HGNC:17422]",{"v":11.3138547684843,"d":"11.31"},{"v":17.3856939434689,"d":"17.39"},{"v":0.650756582122766,"d":"0.65"},{"v":-0.619810095944722,"d":"-0.62"},{"v":0.366088671829009,"d":"0.37"},1,"down","no"]
["MSTRG.7029","LUC7L3","MSTRG.7029.3;MSTRG.7029.5;MSTRG.7029.12;ENST00000393227;ENST00000240304;ENST00000505658;ENST00000506686;ENST00000513969;ENST00000513025;ENST00000503798;ENST00000504065;ENST00000504563;ENST00000508218;ENST00000511068;ENST00000503728;ENST00000511974;ENST00000509335;ENST00000507503;ENST00000512549;ENST00000510984;ENST00000508482;ENST00000509487","GO:0003723(RNA binding);GO:0003729(mRNA binding);GO:0006397(mRNA processing);GO:0008380(RNA splicing);GO:0005634(nucleus);GO:0016607(nuclear speck);GO:0005654(nucleoplasm);GO:0003677(DNA binding);GO:0005685(U1 snRNP);GO:0006376(mRNA splice site selection);GO:0005515(protein binding);GO:0071004(U2-type prespliceosome);GO:0071004(U2-type prespliceosome)","NA","NA","NA","LUC7 like 3 pre-mRNA splicing factor [Source:HGNC Symbol;Acc:HGNC:24309]",{"v":7.3041678047255,"d":"7.30"},{"v":4.93453984781098,"d":"4.93"},{"v":1.48021254868693,"d":"1.48"},{"v":0.56580435215124,"d":"0.57"},{"v":0.368232167216198,"d":"0.37"},1,"up","no"]
["MSTRG.1830","ANXA11","ENST00000372231;ENST00000422982;ENST00000463657;ENST00000265447;ENST00000438331;ENST00000437799;ENST00000463340;ENST00000481805;ENST00000447489;ENST00000474545","GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0005509(calcium ion binding);GO:0051301(cell division);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0042470(melanosome);GO:0007049(cell cycle);GO:0005544(calcium-dependent phospholipid binding);GO:0005819(spindle);GO:0030496(midbody);GO:0070062(extracellular exosome);GO:0048306(calcium-dependent protein binding);GO:0032506(cytokinetic process);GO:0042581(specific granule);GO:0042582(azurophil granule);GO:0006909(phagocytosis);GO:0005635(nuclear envelope);GO:0044548(S100 protein binding);GO:0051592(response to calcium ion);GO:0045335(phagocytic vesicle);GO:0023026(MHC class II protein complex binding);GO:0008429(phosphatidylethanolamine binding);GO:0008429(phosphatidylethanolamine binding)","NA","NA","NA","annexin A11 [Source:HGNC Symbol;Acc:HGNC:535]",{"v":10.1258818067661,"d":"10.13"},{"v":15.5296029104898,"d":"15.53"},{"v":0.652037393688048,"d":"0.65"},{"v":-0.616973390950403,"d":"-0.62"},{"v":0.368295720425859,"d":"0.37"},1,"down","no"]
["ENSG00000281005","LINC00921","ENST00000573951","NA","NA","NA","NA","long intergenic non-protein coding RNA 921 [Source:HGNC Symbol;Acc:HGNC:26830]",{"v":1.774443,"d":"1.77"},{"v":2.730211,"d":"2.73"},{"v":0.649928888280063,"d":"0.65"},{"v":-0.62164622003559,"d":"-0.62"},{"v":0.370578307797467,"d":"0.37"},1,"down","no"]
["MSTRG.6829","STAT3","MSTRG.6829.4;ENST00000588969;ENST00000585517;MSTRG.6829.3;ENST00000264657;MSTRG.6829.2;ENST00000404395;ENST00000471989;ENST00000389272;ENST00000462286;ENST00000498330;ENST00000478276;ENST00000585360;ENST00000462269;ENST00000590776;ENST00000491272;ENST00000588065","GO:0035278(miRNA mediated inhibition of translation);GO:0010628(positive regulation of gene expression);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0005737(cytoplasm);GO:1904685(positive regulation of metalloendopeptidase activity);GO:0005634(nucleus);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0016310(phosphorylation);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0007165(signal transduction);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0004871(signal transducer activity);GO:0031490(chromatin DNA binding);GO:0042803(protein homodimerization activity);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0045893(positive regulation of transcription, DNA-templated);GO:0006954(inflammatory response);GO:0042802(identical protein binding);GO:0019901(protein kinase binding);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0016032(viral process);GO:0007399(nervous system development);GO:0035722(interleukin-12-mediated signaling pathway);GO:0019903(protein phosphatase binding);GO:0008134(transcription factor binding);GO:0060259(regulation of feeding behavior);GO:0000790(nuclear chromatin);GO:0051726(regulation of cell cycle);GO:0006928(movement of cell or subcellular component);GO:0044212(transcription regulatory region DNA binding);GO:0090575(RNA polymerase II transcription factor complex);GO:0045747(positive regulation of Notch signaling pathway);GO:0007259(JAK-STAT cascade);GO:0032355(response to estradiol);GO:0032870(cellular response to hormone stimulus);GO:0060396(growth hormone receptor signaling pathway);GO:0042531(positive regulation of tyrosine phosphorylation of STAT protein);GO:1902895(positive regulation of pri-miRNA transcription from RNA polymerase II promoter);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0001103(RNA polymerase II repressing transcription factor binding);GO:0019221(cytokine-mediated signaling pathway);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:0035019(somatic stem cell population maintenance);GO:0060019(radial glial cell differentiation);GO:0042593(glucose homeostasis);GO:0001077(transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0046983(protein dimerization activity);GO:0070102(interleukin-6-mediated signaling pathway);GO:0060397(JAK-STAT cascade involved in growth hormone signaling pathway);GO:0001659(temperature homeostasis);GO:0043066(negative regulation of apoptotic process);GO:0001228(transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding);GO:0072540(T-helper 17 cell lineage commitment);GO:0042755(eating behavior);GO:0019953(sexual reproduction);GO:0004879(RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding);GO:0030522(intracellular receptor signaling pathway);GO:0045648(positive regulation of erythrocyte differentiation);GO:0044321(response to leptin);GO:0033210(leptin-mediated signaling pathway);GO:0000981(RNA polymerase II transcription factor activity, sequence-specific DNA binding);GO:0031730(CCR5 chemokine receptor binding);GO:0035259(glucocorticoid receptor binding);GO:0043565(sequence-specific DNA binding);GO:0001754(eye photoreceptor cell differentiation);GO:0006366(transcription from RNA polymerase II promoter);GO:0006606(protein import into nucleus);GO:0006953(acute-phase response);GO:0007568(aging);GO:0008283(cell proliferation);GO:0008284(positive regulation of cell proliferation);GO:0008285(negative regulation of cell proliferation);GO:0010033(response to organic substance);GO:0010730(negative regulation of hydrogen peroxide biosynthetic process);GO:0014070(response to organic cyclic compound);GO:0019827(stem cell population maintenance);GO:0034097(response to cytokine);GO:0040014(regulation of multicellular organism growth);GO:0042493(response to drug);GO:0042789(mRNA transcription from RNA polymerase II promoter);GO:0043434(response to peptide hormone);GO:0044320(cellular response to leptin stimulus);GO:0045471(response to ethanol);GO:0045820(negative regulation of glycolytic process);GO:0046902(regulation of mitochondrial membrane permeability);GO:0048708(astrocyte differentiation);GO:0060548(negative regulation of cell death);GO:0071345(cellular response to cytokine stimulus);GO:0071407(cellular response to organic cyclic compound);GO:0097009(energy homeostasis);GO:1901215(negative regulation of neuron death);GO:1902728(positive regulation of growth factor dependent skeletal muscle satellite cell proliferation);GO:2000637(positive regulation of gene silencing by miRNA);GO:2000737(negative regulation of stem cell differentiation);GO:2001171(positive regulation of ATP biosynthetic process);GO:2001223(negative regulation of neuron migration);GO:0005739(mitochondrion);GO:0005743(mitochondrial inner membrane);GO:0005743(mitochondrial inner membrane)","04630(Jak-STAT signaling pathway);04066(HIF-1 signaling pathway);04068(FoxO signaling pathway);04217(Necroptosis);04550(Signaling pathways regulating pluripotency of stem cells);04659(Th17 cell differentiation);04062(Chemokine signaling pathway);04920(Adipocytokine signaling pathway);04917(Prolactin signaling pathway);05200(Pathways in cancer);05206(MicroRNAs in cancer);05205(Proteoglycans in cancer);05203(Viral carcinogenesis);05212(Pancreatic cancer);05221(Acute myeloid leukemia);05223(Non-small cell lung cancer);05321(Inflammatiory bowel disease (IBD));04931(Insulin resistance);04933(AGE-RAGE signaling pathway in diabetic complications);05162(Measles);05161(Hepatitis B);05160(Hepatitis C);05167(Kaposi's sarcoma-associated herpesvirus infection);05169(Epstein-Barr virus infection);05145(Toxoplasmosis);01521(EGFR tyrosine kinase inhibitor resistance);01521(EGFR tyrosine kinase inhibitor resistance)","K04692","NA","signal transducer and activator of transcription 3 [Source:HGNC Symbol;Acc:HGNC:11364]",{"v":14.1417818501659,"d":"14.14"},{"v":21.6396397785151,"d":"21.64"},{"v":0.653512812362365,"d":"0.65"},{"v":-0.613712574015165,"d":"-0.61"},{"v":0.370977138857136,"d":"0.37"},1,"down","no"]
["ENSG00000116128","BCL9","ENST00000234739;ENST00000473292;ENST00000497938","GO:0005634(nucleus);GO:0003713(transcription coactivator activity);GO:0008013(beta-catenin binding);GO:0014908(myotube differentiation involved in skeletal muscle regeneration);GO:0035019(somatic stem cell population maintenance);GO:0035914(skeletal muscle cell differentiation);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0060070(canonical Wnt signaling pathway);GO:0005737(cytoplasm);GO:0005794(Golgi apparatus);GO:0005801(cis-Golgi network);GO:0005515(protein binding);GO:0016055(Wnt signaling pathway);GO:0005654(nucleoplasm);GO:1904837(beta-catenin-TCF complex assembly);GO:1904837(beta-catenin-TCF complex assembly)","NA","NA","NA","B-cell CLL/lymphoma 9 [Source:HGNC Symbol;Acc:HGNC:1008]",{"v":2.80060986915888,"d":"2.80"},{"v":1.8977246271028,"d":"1.90"},{"v":1.47577252735266,"d":"1.48"},{"v":0.561470364385452,"d":"0.56"},{"v":0.373223586724392,"d":"0.37"},1,"up","no"]
["ENSG00000168724","DNAJC21","ENST00000342382;ENST00000509626;ENST00000506762;ENST00000382021;ENST00000514237;ENST00000512136","GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0005840(ribosome);GO:0005515(protein binding);GO:0005730(nucleolus);GO:0006457(protein folding);GO:0006457(protein folding)","NA","NA","NA","DnaJ heat shock protein family (Hsp40) member C21 [Source:HGNC Symbol;Acc:HGNC:27030]",{"v":1.97469915125315,"d":"1.97"},{"v":1.33995109488891,"d":"1.34"},{"v":1.47370986805818,"d":"1.47"},{"v":0.55945252639128,"d":"0.56"},{"v":0.374752216503967,"d":"0.37"},1,"up","no"]
["MSTRG.3652","NFYB","ENST00000240055;ENST00000551727;ENST00000550881;ENST00000551446","GO:0005634(nucleus);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0046982(protein heterodimerization activity);GO:0043565(sequence-specific DNA binding);GO:0005515(protein binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0032403(protein complex binding);GO:0044212(transcription regulatory region DNA binding);GO:0045893(positive regulation of transcription, DNA-templated);GO:1990830(cellular response to leukemia inhibitory factor);GO:0016602(CCAAT-binding factor complex);GO:0005654(nucleoplasm);GO:0070491(repressing transcription factor binding);GO:0090575(RNA polymerase II transcription factor complex);GO:0045540(regulation of cholesterol biosynthetic process);GO:0000980(RNA polymerase II distal enhancer sequence-specific DNA binding);GO:0032993(protein-DNA complex);GO:0032993(protein-DNA complex)","04612(Antigen processing and presentation);05152(Tuberculosis);05166(HTLV-I infection);05166(HTLV-I infection)","K08065","NA","nuclear transcription factor Y subunit beta [Source:HGNC Symbol;Acc:HGNC:7805]",{"v":1.29474671529459,"d":"1.29"},{"v":1.98572113801453,"d":"1.99"},{"v":0.652028469913541,"d":"0.65"},{"v":-0.616993135789351,"d":"-0.62"},{"v":0.375423324520625,"d":"0.38"},1,"down","no"]
["MSTRG.15167","HCCS","ENST00000380762;ENST00000380763;ENST00000321143","GO:0016020(membrane);GO:0046872(metal ion binding);GO:0005739(mitochondrion);GO:0005743(mitochondrial inner membrane);GO:0016829(lyase activity);GO:0004408(holocytochrome-c synthase activity);GO:0009887(animal organ morphogenesis);GO:0055114(oxidation-reduction process);GO:0018063(cytochrome c-heme linkage);GO:0018063(cytochrome c-heme linkage)","00860(Porphyrin and chlorophyll metabolism);00860(Porphyrin and chlorophyll metabolism)","K01764","EC:4.4.1.17","holocytochrome c synthase [Source:HGNC Symbol;Acc:HGNC:4837]",{"v":2.44504205781585,"d":"2.45"},{"v":3.73995042269807,"d":"3.74"},{"v":0.653763227174533,"d":"0.65"},{"v":-0.613159864103603,"d":"-0.61"},{"v":0.377463248186259,"d":"0.38"},1,"down","no"]
["MSTRG.917","MCL1;ADAMTSL4-AS1","ENST00000620947;ENST00000307940;ENST00000369026;ENST00000464132;ENST00000615012;MSTRG.917.5;ENST00000617352;MSTRG.917.2","GO:0043066(negative regulation of apoptotic process);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0071806(protein transmembrane transport);GO:0005739(mitochondrion);GO:0042981(regulation of apoptotic process);GO:0005829(cytosol);GO:0005515(protein binding);GO:0006915(apoptotic process);GO:0007275(multicellular organism development);GO:0005741(mitochondrial outer membrane);GO:0030154(cell differentiation);GO:0005654(nucleoplasm);GO:0046982(protein heterodimerization activity);GO:0001709(cell fate determination);GO:0042803(protein homodimerization activity);GO:2000811(negative regulation of anoikis);GO:0008630(intrinsic apoptotic signaling pathway in response to DNA damage);GO:0010507(negative regulation of autophagy);GO:0034097(response to cytokine);GO:0019725(cellular homeostasis);GO:2001240(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand);GO:2001020(regulation of response to DNA damage stimulus);GO:0097192(extrinsic apoptotic signaling pathway in absence of ligand);GO:0097136(Bcl-2 family protein complex);GO:0015266(protein channel activity);GO:0051434(BH3 domain binding);GO:0008637(apoptotic mitochondrial changes);GO:1903378(positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway);GO:2001243(negative regulation of intrinsic apoptotic signaling pathway);GO:0005759(mitochondrial matrix);GO:0005759(mitochondrial matrix)","04630(Jak-STAT signaling pathway);04151(PI3K-Akt signaling pathway);04210(Apoptosis);05206(MicroRNAs in cancer);05206(MicroRNAs in cancer)","K02539","NA","MCL1, BCL2 family apoptosis regulator [Source:HGNC Symbol;Acc:HGNC:6943];ADAMTSL4 antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:32041]",{"v":17.5303494138623,"d":"17.53"},{"v":26.6561759716614,"d":"26.66"},{"v":0.657646821978482,"d":"0.66"},{"v":-0.604615077754237,"d":"-0.60"},{"v":0.378138995794425,"d":"0.38"},1,"down","no"]
["MSTRG.12285","C5orf56;RAD50;AC116366.3","ENST00000378953;ENST00000378947;ENST00000337752;ENST00000378823;ENST00000638568;ENST00000407797;ENST00000453394;ENST00000461203;ENST00000621237;ENST00000434288;ENST00000455677;ENST00000496204;ENST00000612967;ENST00000639899;ENST00000638504","GO:0005634(nucleus);GO:0016020(membrane);GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0005654(nucleoplasm);GO:0016787(hydrolase activity);GO:0005694(chromosome);GO:0006281(DNA repair);GO:0090305(nucleic acid phosphodiester bond hydrolysis);GO:0005515(protein binding);GO:0000723(telomere maintenance);GO:0006310(DNA recombination);GO:0006974(cellular response to DNA damage stimulus);GO:0007049(cell cycle);GO:0051321(meiotic cell cycle);GO:0030870(Mre11 complex);GO:0016887(ATPase activity);GO:0000781(chromosome, telomeric region);GO:0000790(nuclear chromatin);GO:0046939(nucleotide phosphorylation);GO:0000784(nuclear chromosome, telomeric region);GO:0016032(viral process);GO:0030674(protein binding, bridging);GO:1901796(regulation of signal transduction by p53 class mediator);GO:0006260(DNA replication);GO:0003677(DNA binding);GO:0000731(DNA synthesis involved in DNA repair);GO:0000732(strand displacement);GO:0007131(reciprocal meiotic recombination);GO:0035861(site of double-strand break);GO:0006302(double-strand break repair);GO:0008408(3'-5' exonuclease activity);GO:0000724(double-strand break repair via homologous recombination);GO:0004003(ATP-dependent DNA helicase activity);GO:0000729(DNA double-strand break processing);GO:0006303(double-strand break repair via nonhomologous end joining);GO:0031860(telomeric 3' overhang formation);GO:0031954(positive regulation of protein autophosphorylation);GO:0032206(positive regulation of telomere maintenance);GO:0032508(DNA duplex unwinding);GO:0033674(positive regulation of kinase activity);GO:1904354(negative regulation of telomere capping);GO:0000014(single-stranded DNA endodeoxyribonuclease activity);GO:0007004(telomere maintenance via telomerase);GO:0070192(chromosome organization involved in meiotic cell cycle);GO:0000794(condensed nuclear chromosome);GO:0003691(double-stranded telomeric DNA binding);GO:0004017(adenylate kinase activity);GO:0043047(single-stranded telomeric DNA binding);GO:0051880(G-quadruplex DNA binding);GO:0000019(regulation of mitotic recombination);GO:0000722(telomere maintenance via recombination);GO:0000722(telomere maintenance via recombination)","03440(Homologous recombination);03450(Non-homologous end-joining);04218(Cellular senescence);04218(Cellular senescence)","K10866","EC:3.6.-.-","chromosome 5 open reading frame 56 [Source:HGNC Symbol;Acc:HGNC:33838];RAD50 double strand break repair protein [Source:HGNC Symbol;Acc:HGNC:9816]",{"v":1.94813784066737,"d":"1.95"},{"v":1.32909848661727,"d":"1.33"},{"v":1.4657588284715,"d":"1.47"},{"v":0.551647746315618,"d":"0.55"},{"v":0.379351385253203,"d":"0.38"},1,"up","no"]
["ENSG00000151458","ANKRD50","ENST00000504087","GO:0006810(transport);GO:0015031(protein transport);GO:0005515(protein binding);GO:0005768(endosome);GO:1990126(retrograde transport, endosome to plasma membrane)","NA","NA","NA","ankyrin repeat domain 50 [Source:HGNC Symbol;Acc:HGNC:29223]",{"v":0.809956,"d":"0.81"},{"v":0.548859,"d":"0.55"},{"v":1.4757086974979,"d":"1.48"},{"v":0.561407963842864,"d":"0.56"},{"v":0.379522517443786,"d":"0.38"},1,"up","no"]
["MSTRG.8005","C19orf60","ENST00000358607;ENST00000450195;ENST00000597371;ENST00000598375;ENST00000595077;ENST00000601736;ENST00000600997","GO:0005515(protein binding);GO:0005515(protein binding)","NA","NA","NA","chromosome 19 open reading frame 60 [Source:HGNC Symbol;Acc:HGNC:26098]",{"v":2.83921860771513,"d":"2.84"},{"v":1.93448631127596,"d":"1.93"},{"v":1.46768606795797,"d":"1.47"},{"v":0.553543414615482,"d":"0.55"},{"v":0.382027755847412,"d":"0.38"},1,"up","no"]
["MSTRG.8642","RMDN2","ENST00000354545;ENST00000407257;ENST00000496735;ENST00000425641;ENST00000440353;ENST00000469469;ENST00000402091;ENST00000406384","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005829(cytosol);GO:0005737(cytoplasm);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0005874(microtubule);GO:0000922(spindle pole);GO:0005819(spindle);GO:0005819(spindle)","NA","NA","NA","regulator of microtubule dynamics 2 [Source:HGNC Symbol;Acc:HGNC:26567]",{"v":0.230181123520587,"d":"0.23"},{"v":0.354230499583264,"d":"0.35"},{"v":0.649806055072572,"d":"0.65"},{"v":-0.621918907725859,"d":"-0.62"},{"v":0.383333058528547,"d":"0.38"},1,"down","no"]
["ENSG00000070018","LRP6","ENST00000261349;ENST00000538239","GO:0051091(positive regulation of sequence-specific DNA binding transcription factor activity);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0090263(positive regulation of canonical Wnt signaling pathway);GO:0034392(negative regulation of smooth muscle cell apoptotic process);GO:0045787(positive regulation of cell cycle);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0060070(canonical Wnt signaling pathway);GO:0005783(endoplasmic reticulum);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0007275(multicellular organism development);GO:0016055(Wnt signaling pathway);GO:0031410(cytoplasmic vesicle);GO:0045121(membrane raft);GO:0042813(Wnt-activated receptor activity);GO:0005576(extracellular region);GO:0042802(identical protein binding);GO:0006897(endocytosis);GO:0090090(negative regulation of canonical Wnt signaling pathway);GO:0017147(Wnt-protein binding);GO:0009880(embryonic pattern specification);GO:0045202(synapse);GO:0042803(protein homodimerization activity);GO:0009986(cell surface);GO:0045893(positive regulation of transcription, DNA-templated);GO:0007268(chemical synaptic transmission);GO:1901998(toxin transport);GO:0005109(frizzled binding);GO:0005102(receptor binding);GO:0001933(negative regulation of protein phosphorylation);GO:0006469(negative regulation of protein kinase activity);GO:1904886(beta-catenin destruction complex disassembly);GO:0044340(canonical Wnt signaling pathway involved in regulation of cell proliferation);GO:0005769(early endosome);GO:1904948(midbrain dopaminergic neuron differentiation);GO:0043025(neuronal cell body);GO:0071542(dopaminergic neuron differentiation);GO:0005901(caveola);GO:0005794(Golgi apparatus);GO:0043235(receptor complex);GO:1904928(coreceptor activity involved in canonical Wnt signaling pathway);GO:0044332(Wnt signaling pathway involved in dorsal/ventral axis specification);GO:0060828(regulation of canonical Wnt signaling pathway);GO:0071901(negative regulation of protein serine/threonine kinase activity);GO:1990851(Wnt-Frizzled-LRP5/6 complex);GO:1990909(Wnt signalosome);GO:0021987(cerebral cortex development);GO:0005041(low-density lipoprotein receptor activity);GO:0019210(kinase inhibitor activity);GO:0019534(toxin transporter activity);GO:0034185(apolipoprotein binding);GO:0071936(coreceptor activity involved in Wnt signaling pathway);GO:0001843(neural tube closure);GO:0003344(pericardium morphogenesis);GO:0006355(regulation of transcription, DNA-templated);GO:0007204(positive regulation of cytosolic calcium ion concentration);GO:0014029(neural crest formation);GO:0014033(neural crest cell differentiation);GO:0016337(single organismal cell-cell adhesion);GO:0021587(cerebellum morphogenesis);GO:0021794(thalamus development);GO:0030917(midbrain-hindbrain boundary development);GO:0035261(external genitalia morphogenesis);GO:0042475(odontogenesis of dentin-containing tooth);GO:0043434(response to peptide hormone);GO:0044335(canonical Wnt signaling pathway involved in neural crest cell differentiation);GO:0060021(palate development);GO:0060026(convergent extension);GO:0060059(embryonic retina morphogenesis in camera-type eye);GO:0060325(face morphogenesis);GO:0060535(trachea cartilage morphogenesis);GO:0071397(cellular response to cholesterol);GO:0072659(protein localization to plasma membrane);GO:0090009(primitive streak formation);GO:0090118(receptor-mediated endocytosis involved in cholesterol transport);GO:0090244(Wnt signaling pathway involved in somitogenesis);GO:0090245(axis elongation involved in somitogenesis);GO:1904953(Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation);GO:2000055(positive regulation of Wnt signaling pathway involved in dorsal/ventral axis specification);GO:0031901(early endosome membrane);GO:0031901(early endosome membrane)","04310(Wnt signaling pathway);04150(mTOR signaling pathway);05200(Pathways in cancer);05225(Hepatocellular carcinoma);05226(Gastric cancer);05224(Breast cancer);05224(Breast cancer)","K03068","NA","LDL receptor related protein 6 [Source:HGNC Symbol;Acc:HGNC:6698]",{"v":0.136746779529844,"d":"0.14"},{"v":0.0912297881396924,"d":"0.09"},{"v":1.49892685621998,"d":"1.50"},{"v":0.583929985191497,"d":"0.58"},{"v":0.383627599992104,"d":"0.38"},1,"up","no"]
["MSTRG.14430","CA2","ENST00000285379;ENST00000520127;ENST00000522742;ENST00000520996","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0016829(lyase activity);GO:0006730(one-carbon metabolic process);GO:0005886(plasma membrane);GO:0004089(carbonate dehydratase activity);GO:0005515(protein binding);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0015701(bicarbonate transport);GO:0038166(angiotensin-activated signaling pathway);GO:0045177(apical part of cell);GO:0004064(arylesterase activity);GO:0001822(kidney development);GO:0002009(morphogenesis of an epithelium);GO:0009268(response to pH);GO:0010033(response to organic substance);GO:0010043(response to zinc ion);GO:0015670(carbon dioxide transport);GO:0032230(positive regulation of synaptic transmission, GABAergic);GO:0032849(positive regulation of cellular pH reduction);GO:0042475(odontogenesis of dentin-containing tooth);GO:0043627(response to estrogen);GO:0044070(regulation of anion transport);GO:0045672(positive regulation of osteoclast differentiation);GO:0045780(positive regulation of bone resorption);GO:0046903(secretion);GO:0048545(response to steroid hormone);GO:0051453(regulation of intracellular pH);GO:0071498(cellular response to fluid shear stress);GO:2001150(positive regulation of dipeptide transmembrane transport);GO:2001225(regulation of chloride transport);GO:0005615(extracellular space);GO:0005902(microvillus);GO:0016323(basolateral plasma membrane);GO:0030424(axon);GO:0043209(myelin sheath);GO:0043209(myelin sheath)","00910(Nitrogen metabolism);04971(Gastric acid secretion);04972(Pancreatic secretion);04976(Bile secretion);04964(Proximal tubule bicarbonate reclamation);04966(Collecting duct acid secretion);04966(Collecting duct acid secretion)","K18245","EC:4.2.1.1","carbonic anhydrase 2 [Source:HGNC Symbol;Acc:HGNC:1373]",{"v":5.91529850918512,"d":"5.92"},{"v":8.9712951328309,"d":"8.97"},{"v":0.659358367058708,"d":"0.66"},{"v":-0.600865299074325,"d":"-0.60"},{"v":0.385604315716131,"d":"0.39"},1,"down","no"]
["ENSG00000109519","GRPEL1","ENST00000264954;ENST00000504920;ENST00000514056;ENST00000509696","GO:0005634(nucleus);GO:0005739(mitochondrion);GO:0006457(protein folding);GO:0050790(regulation of catalytic activity);GO:0042803(protein homodimerization activity);GO:0005759(mitochondrial matrix);GO:0051087(chaperone binding);GO:0000774(adenyl-nucleotide exchange factor activity);GO:0051082(unfolded protein binding);GO:0030150(protein import into mitochondrial matrix);GO:0001405(presequence translocase-associated import motor);GO:0001405(presequence translocase-associated import motor)","NA","NA","NA","GrpE like 1, mitochondrial [Source:HGNC Symbol;Acc:HGNC:19696]",{"v":1.73585129997606,"d":"1.74"},{"v":2.62465716255686,"d":"2.62"},{"v":0.661363062856197,"d":"0.66"},{"v":-0.596485621662929,"d":"-0.60"},{"v":0.386832295513502,"d":"0.39"},1,"down","no"]
["MSTRG.11157","SEC61A1","ENST00000243253;ENST00000498837;ENST00000481210;ENST00000491668;ENST00000464451;ENST00000483956","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0015031(protein transport);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005515(protein binding);GO:0043022(ribosome binding);GO:0005829(cytosol);GO:0034341(response to interferon-gamma);GO:0039019(pronephric nephron development);GO:0005791(rough endoplasmic reticulum);GO:0045047(protein targeting to ER);GO:0030176(integral component of endoplasmic reticulum membrane);GO:0036498(IRE1-mediated unfolded protein response);GO:0006614(SRP-dependent cotranslational protein targeting to membrane);GO:0006620(posttranslational protein targeting to endoplasmic reticulum membrane);GO:0007029(endoplasmic reticulum organization);GO:0016049(cell growth);GO:0016049(cell growth)","03060(Protein export);04141(Protein processing in endoplasmic reticulum);04145(Phagosome);05110(Vibrio cholerae infection);05110(Vibrio cholerae infection)","K10956","NA","Sec61 translocon alpha 1 subunit [Source:HGNC Symbol;Acc:HGNC:18276]",{"v":20.1051063615073,"d":"20.11"},{"v":13.8263015484352,"d":"13.83"},{"v":1.45412034382996,"d":"1.45"},{"v":0.540146672463879,"d":"0.54"},{"v":0.387626917343829,"d":"0.39"},1,"up","no"]
["ENSG00000119397","CNTRL","ENST00000373845;ENST00000373855;ENST00000373850;ENST00000373847;ENST00000613863;ENST00000373865;ENST00000373851;ENST00000238341;ENST00000491018","GO:0051301(cell division);GO:0000278(mitotic cell cycle);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005829(cytosol);GO:0018108(peptidyl-tyrosine phosphorylation);GO:0005813(centrosome);GO:0005856(cytoskeleton);GO:0007049(cell cycle);GO:0005815(microtubule organizing center);GO:0030496(midbody);GO:0005515(protein binding);GO:0000086(G2/M transition of mitotic cell cycle);GO:0010389(regulation of G2/M transition of mitotic cell cycle);GO:0097711(ciliary basal body docking);GO:0004713(protein tyrosine kinase activity);GO:0004713(protein tyrosine kinase activity)","NA","NA","NA","centriolin [Source:HGNC Symbol;Acc:HGNC:1858]",{"v":4.4544149753637,"d":"4.45"},{"v":3.06044922586811,"d":"3.06"},{"v":1.45547749582422,"d":"1.46"},{"v":0.541492533096003,"d":"0.54"},{"v":0.387993831015656,"d":"0.39"},1,"up","no"]
["ENSG00000178297","TMPRSS9","ENST00000332578;ENST00000613480;ENST00000395264","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016787(hydrolase activity);GO:0005887(integral component of plasma membrane);GO:0005886(plasma membrane);GO:0008233(peptidase activity);GO:0006508(proteolysis);GO:0004252(serine-type endopeptidase activity);GO:0008236(serine-type peptidase activity);GO:0008236(serine-type peptidase activity)","NA","NA","NA","transmembrane protease, serine 9 [Source:HGNC Symbol;Acc:HGNC:30079]",{"v":0.608212014064362,"d":"0.61"},{"v":0.92849140738975,"d":"0.93"},{"v":0.655054003972117,"d":"0.66"},{"v":-0.61031424464782,"d":"-0.61"},{"v":0.389373176567219,"d":"0.39"},1,"down","no"]
["ENSG00000265531","FCGR1CP","ENST00000579737","NA","NA","NA","NA","Fc fragment of IgG receptor Ic, pseudogene [Source:HGNC Symbol;Acc:HGNC:3615]",{"v":2.416229,"d":"2.42"},{"v":3.66588,"d":"3.67"},{"v":0.659112955143103,"d":"0.66"},{"v":-0.601402367346869,"d":"-0.60"},{"v":0.390149489775404,"d":"0.39"},1,"down","no"]
["MSTRG.14043","ZYX","ENST00000322764;MSTRG.14043.3;ENST00000354434;ENST00000468083;ENST00000457235;ENST00000477373;ENST00000497119;ENST00000392910;ENST00000436448;ENST00000446634","GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0005829(cytosol);GO:0007155(cell adhesion);GO:0005925(focal adhesion);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0030054(cell junction);GO:0007229(integrin-mediated signaling pathway);GO:0001725(stress fiber);GO:0016032(viral process);GO:0005887(integral component of plasma membrane);GO:0005886(plasma membrane);GO:0007165(signal transduction);GO:0007267(cell-cell signaling);GO:0007179(transforming growth factor beta receptor signaling pathway);GO:0007160(cell-matrix adhesion);GO:0043149(stress fiber assembly);GO:0005913(cell-cell adherens junction);GO:0050727(regulation of inflammatory response);GO:0050727(regulation of inflammatory response)","04510(Focal adhesion);04510(Focal adhesion)","K06273","NA","zyxin [Source:HGNC Symbol;Acc:HGNC:13200]",{"v":90.4966089827685,"d":"90.50"},{"v":136.091885139575,"d":"136.09"},{"v":0.664966973526421,"d":"0.66"},{"v":-0.588645405871821,"d":"-0.59"},{"v":0.391182428247737,"d":"0.39"},1,"down","no"]
["MSTRG.12526","C5orf58","ENST00000524171;ENST00000421269;ENST00000518395;ENST00000521850","NA","NA","NA","NA","chromosome 5 open reading frame 58 [Source:HGNC Symbol;Acc:HGNC:37272]",{"v":0.301802387652773,"d":"0.30"},{"v":0.469394439360702,"d":"0.47"},{"v":0.64296114812058,"d":"0.64"},{"v":-0.637196531684418,"d":"-0.64"},{"v":0.392514016595193,"d":"0.39"},1,"down","no"]
["ENSG00000101391","CDK5RAP1","ENST00000461710;ENST00000346416;ENST00000473791;ENST00000481964;ENST00000488723;ENST00000461356;ENST00000357886;ENST00000477105;ENST00000471264;ENST00000339269","GO:0051539(4 iron, 4 sulfur cluster binding);GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0003824(catalytic activity);GO:0016740(transferase activity);GO:0051536(iron-sulfur cluster binding);GO:0006400(tRNA modification);GO:0035600(tRNA methylthiolation);GO:0005575(cellular_component);GO:0019901(protein kinase binding);GO:0045736(negative regulation of cyclin-dependent protein serine/threonine kinase activity);GO:0007420(brain development);GO:0045664(regulation of neuron differentiation);GO:0032403(protein complex binding);GO:0035597(N6-isopentenyladenosine methylthiotransferase activity);GO:0000079(regulation of cyclin-dependent protein serine/threonine kinase activity);GO:0045903(positive regulation of translational fidelity);GO:0070131(positive regulation of mitochondrial translation);GO:0070900(mitochondrial tRNA modification);GO:0005739(mitochondrion);GO:0005739(mitochondrion)","NA","NA","NA","CDK5 regulatory subunit associated protein 1 [Source:HGNC Symbol;Acc:HGNC:15880]",{"v":2.37989509984673,"d":"2.38"},{"v":1.63558631683819,"d":"1.64"},{"v":1.45507153938986,"d":"1.46"},{"v":0.541090085769817,"d":"0.54"},{"v":0.393168839180741,"d":"0.39"},1,"up","no"]
["ENSG00000184060","ADAP2","ENST00000330889;ENST00000581285;ENST00000584989;ENST00000580526;ENST00000480980;ENST00000470962;ENST00000585130;ENST00000580525","GO:0046872(metal ion binding);GO:0043547(positive regulation of GTPase activity);GO:0005096(GTPase activator activity);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0007507(heart development);GO:0005546(phosphatidylinositol-4,5-bisphosphate binding);GO:0005547(phosphatidylinositol-3,4,5-trisphosphate binding);GO:0043325(phosphatidylinositol-3,4-bisphosphate binding);GO:0030674(protein binding, bridging);GO:0043533(inositol 1,3,4,5 tetrakisphosphate binding);GO:0005740(mitochondrial envelope);GO:0005740(mitochondrial envelope)","NA","NA","NA","ArfGAP with dual PH domains 2 [Source:HGNC Symbol;Acc:HGNC:16487]",{"v":2.84484989173333,"d":"2.84"},{"v":1.95782163413333,"d":"1.96"},{"v":1.4530689834739,"d":"1.45"},{"v":0.539103195574533,"d":"0.54"},{"v":0.394949144304796,"d":"0.39"},1,"up","no"]
["MSTRG.391","AZIN2","ENST00000492521;ENST00000471119;ENST00000478204;ENST00000481886;ENST00000495135;ENST00000497710;ENST00000294517;ENST00000484656;ENST00000373440;ENST00000492420;ENST00000475935","GO:0006810(transport);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005829(cytosol);GO:0003824(catalytic activity);GO:0005794(Golgi apparatus);GO:0042995(cell projection);GO:0005515(protein binding);GO:0048471(perinuclear region of cytoplasm);GO:0031410(cytoplasmic vesicle);GO:0042978(ornithine decarboxylase activator activity);GO:0006596(polyamine biosynthetic process);GO:0007283(spermatogenesis);GO:0030425(dendrite);GO:0030424(axon);GO:0043204(perikaryon);GO:0005802(trans-Golgi network);GO:0042177(negative regulation of protein catabolic process);GO:0030133(transport vesicle);GO:0033387(putrescine biosynthetic process from ornithine);GO:1902269(positive regulation of polyamine transmembrane transport);GO:0005793(endoplasmic reticulum-Golgi intermediate compartment);GO:0033116(endoplasmic reticulum-Golgi intermediate compartment membrane);GO:0005801(cis-Golgi network);GO:0043085(positive regulation of catalytic activity);GO:0008792(arginine decarboxylase activity);GO:0015489(putrescine transmembrane transporter activity);GO:0015847(putrescine transport);GO:0097055(agmatine biosynthetic process);GO:0098629(trans-Golgi network membrane organization);GO:1990005(granular vesicle);GO:0006591(ornithine metabolic process);GO:0005739(mitochondrion);GO:0005739(mitochondrion)","00330(Arginine and proline metabolism);00330(Arginine and proline metabolism)","K01583","EC:4.1.1.19","antizyme inhibitor 2 [Source:HGNC Symbol;Acc:HGNC:29957]",{"v":0.188208886110688,"d":"0.19"},{"v":0.123245866900442,"d":"0.12"},{"v":1.52710099611473,"d":"1.53"},{"v":0.610795479145599,"d":"0.61"},{"v":0.395792480799698,"d":"0.40"},1,"up","no"]
["ENSG00000165424","ZCCHC24","ENST00000372336","GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0008270(zinc ion binding);GO:0046872(metal ion binding)","NA","NA","NA","zinc finger CCHC-type containing 24 [Source:HGNC Symbol;Acc:HGNC:26911]",{"v":0.68268090734508,"d":"0.68"},{"v":1.03029284379331,"d":"1.03"},{"v":0.6626086082784,"d":"0.66"},{"v":-0.593771148576968,"d":"-0.59"},{"v":0.396126063582803,"d":"0.40"},1,"down","no"]
["ENSG00000178199","ZC3H12D","ENST00000409806;ENST00000409948;ENST00000462655;ENST00000458251","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0005654(nucleoplasm);GO:0016787(hydrolase activity);GO:0090305(nucleic acid phosphodiester bond hydrolysis);GO:0004519(endonuclease activity);GO:0004518(nuclease activity);GO:0000932(P-body);GO:0005515(protein binding);GO:0061158(3'-UTR-mediated mRNA destabilization);GO:0061158(3'-UTR-mediated mRNA destabilization)","NA","NA","NA","zinc finger CCCH-type containing 12D [Source:HGNC Symbol;Acc:HGNC:21175]",{"v":1.65351681449577,"d":"1.65"},{"v":1.14082085741868,"d":"1.14"},{"v":1.44940969806352,"d":"1.45"},{"v":0.535465452603038,"d":"0.54"},{"v":0.397211279758393,"d":"0.40"},1,"up","no"]
["ENSG00000089123","TASP1","ENST00000337743;ENST00000465381;ENST00000476108;ENST00000480436","GO:0016787(hydrolase activity);GO:0008233(peptidase activity);GO:0006508(proteolysis);GO:0045893(positive regulation of transcription, DNA-templated);GO:0004298(threonine-type endopeptidase activity);GO:0004298(threonine-type endopeptidase activity)","NA","NA","NA","taspase 1 [Source:HGNC Symbol;Acc:HGNC:15859]",{"v":0.691828857831325,"d":"0.69"},{"v":0.463945413769363,"d":"0.46"},{"v":1.49118589665647,"d":"1.49"},{"v":0.576460120442822,"d":"0.58"},{"v":0.397635208564704,"d":"0.40"},1,"up","no"]
["ENSG00000158292","GPR153","ENST00000377893","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0004930(G-protein coupled receptor activity);GO:0007186(G-protein coupled receptor signaling pathway);GO:0005886(plasma membrane);GO:0004871(signal transducer activity);GO:0007165(signal transduction)","NA","NA","NA","G protein-coupled receptor 153 [Source:HGNC Symbol;Acc:HGNC:23618]",{"v":0.75325,"d":"0.75"},{"v":0.514361,"d":"0.51"},{"v":1.46443840026752,"d":"1.46"},{"v":0.550347509367746,"d":"0.55"},{"v":0.400381313170807,"d":"0.40"},1,"up","no"]
["MSTRG.7917","AKAP8","ENST00000269701;ENST00000598597;ENST00000595416;ENST00000599883;ENST00000537303","GO:0005634(nucleus);GO:0003723(RNA binding);GO:0006810(transport);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0015031(protein transport);GO:0046872(metal ion binding);GO:0005654(nucleoplasm);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0002376(immune system process);GO:0045087(innate immune response);GO:0005730(nucleolus);GO:0007165(signal transduction);GO:0016363(nuclear matrix);GO:0000278(mitotic cell cycle);GO:0042826(histone deacetylase binding);GO:0034237(protein kinase A regulatory subunit binding);GO:0003690(double-stranded DNA binding);GO:0008270(zinc ion binding);GO:0051059(NF-kappaB binding);GO:0007076(mitotic chromosome condensation);GO:0031065(positive regulation of histone deacetylation);GO:0032720(negative regulation of tumor necrosis factor production);GO:0033127(regulation of histone phosphorylation);GO:0044839(cell cycle G2/M phase transition);GO:0071222(cellular response to lipopolysaccharide);GO:0071380(cellular response to prostaglandin E stimulus);GO:0000793(condensed chromosome);GO:0001939(female pronucleus);GO:0005739(mitochondrion);GO:0005794(Golgi apparatus);GO:0005794(Golgi apparatus)","NA","NA","NA","A-kinase anchoring protein 8 [Source:HGNC Symbol;Acc:HGNC:378]",{"v":4.2576269310987,"d":"4.26"},{"v":2.95472996159218,"d":"2.95"},{"v":1.44095297588699,"d":"1.44"},{"v":0.527023255317239,"d":"0.53"},{"v":0.402115208869558,"d":"0.40"},1,"up","no"]
["ENSG00000137103","TMEM8B","ENST00000464519;ENST00000377988;ENST00000490199;ENST00000472010;ENST00000377991;ENST00000439587;ENST00000377996","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0007155(cell adhesion);GO:0005783(endoplasmic reticulum);GO:0005739(mitochondrion);GO:0005886(plasma membrane);GO:0040008(regulation of growth);GO:0005515(protein binding);GO:0007160(cell-matrix adhesion);GO:0007346(regulation of mitotic cell cycle);GO:0009986(cell surface);GO:0009986(cell surface)","NA","NA","NA","transmembrane protein 8B [Source:HGNC Symbol;Acc:HGNC:21427]",{"v":0.2349577424139,"d":"0.23"},{"v":0.161961560099286,"d":"0.16"},{"v":1.45070066174879,"d":"1.45"},{"v":0.536749863745134,"d":"0.54"},{"v":0.402438106830774,"d":"0.40"},1,"up","no"]
["MSTRG.4498","ACTN1","ENST00000193403;ENST00000556083;ENST00000553882;ENST00000556433;ENST00000438964;ENST00000556203;ENST00000553659;ENST00000376839;ENST00000544964;ENST00000554508;ENST00000556343;ENST00000555616;ENST00000553779;ENST00000556432;ENST00000555075;ENST00000538545;ENST00000556571;ENST00000394419;ENST00000553370","GO:0051015(actin filament binding);GO:0003779(actin binding);GO:0051017(actin filament bundle assembly);GO:0051764(actin crosslink formation);GO:0005509(calcium ion binding);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0046872(metal ion binding);GO:0042803(protein homodimerization activity);GO:0005886(plasma membrane);GO:0005856(cytoskeleton);GO:0042995(cell projection);GO:0005515(protein binding);GO:1903506(regulation of nucleic acid-templated transcription);GO:0005615(extracellular space);GO:0030054(cell junction);GO:0030374(ligand-dependent nuclear receptor transcription coactivator activity);GO:0005925(focal adhesion);GO:0005576(extracellular region);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0005622(intracellular);GO:0001725(stress fiber);GO:0044325(ion channel binding);GO:0042981(regulation of apoptotic process);GO:0001726(ruffle);GO:0002576(platelet degranulation);GO:0048041(focal adhesion assembly);GO:0005178(integrin binding);GO:0031093(platelet alpha granule lumen);GO:0005911(cell-cell junction);GO:0005884(actin filament);GO:0030018(Z disc);GO:0007015(actin filament organization);GO:0017166(vinculin binding);GO:0003725(double-stranded RNA binding);GO:0031143(pseudopodium);GO:0030220(platelet formation);GO:0051271(negative regulation of cellular component movement);GO:0036344(platelet morphogenesis);GO:0051639(actin filament network formation);GO:0005903(brush border);GO:0005916(fascia adherens);GO:0030017(sarcomere);GO:0030017(sarcomere)","04510(Focal adhesion);04520(Adherens junction);04530(Tight junction);04810(Regulation of actin cytoskeleton);04670(Leukocyte transendothelial migration);05203(Viral carcinogenesis);05322(Systemic lupus erythematosus);05146(Amoebiasis);05146(Amoebiasis)","K05699","NA","actinin alpha 1 [Source:HGNC Symbol;Acc:HGNC:163]",{"v":16.7519342572934,"d":"16.75"},{"v":24.947312003482,"d":"24.95"},{"v":0.671492554186009,"d":"0.67"},{"v":-0.57455669240289,"d":"-0.57"},{"v":0.403256868561119,"d":"0.40"},1,"down","no"]
["ENSG00000187862","TTC24","ENST00000478081;ENST00000368236;ENST00000413282;ENST00000368237;ENST00000462049","NA","NA","NA","NA","tetratricopeptide repeat domain 24 [Source:HGNC Symbol;Acc:HGNC:32348]",{"v":1.15485578296218,"d":"1.15"},{"v":0.798443596323789,"d":"0.80"},{"v":1.44638367478854,"d":"1.45"},{"v":0.532450299379476,"d":"0.53"},{"v":0.404989408236712,"d":"0.40"},1,"up","no"]
["ENSG00000123179","EBPL","ENST00000378268;ENST00000378272;ENST00000473576;ENST00000495963;ENST00000378270;ENST00000378284;ENST00000242827","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0047750(cholestenol delta-isomerase activity);GO:0016125(sterol metabolic process);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005789(endoplasmic reticulum membrane)","NA","NA","NA","emopamil binding protein like [Source:HGNC Symbol;Acc:HGNC:18061]",{"v":1.21737972,"d":"1.22"},{"v":0.827587918,"d":"0.83"},{"v":1.47099745359018,"d":"1.47"},{"v":0.556794749178741,"d":"0.56"},{"v":0.407239451822823,"d":"0.41"},1,"up","no"]
["MSTRG.14389","TRAM1","ENST00000262213;ENST00000521425;MSTRG.14389.1;ENST00000518678;ENST00000521049","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005783(endoplasmic reticulum);GO:0006810(transport);GO:0015031(protein transport);GO:0005789(endoplasmic reticulum membrane);GO:0005515(protein binding);GO:0016032(viral process);GO:0004872(receptor activity);GO:0006613(cotranslational protein targeting to membrane);GO:0006613(cotranslational protein targeting to membrane)","04141(Protein processing in endoplasmic reticulum);04141(Protein processing in endoplasmic reticulum)","K14010","NA","translocation associated membrane protein 1 [Source:HGNC Symbol;Acc:HGNC:20568]",{"v":18.1253634846324,"d":"18.13"},{"v":26.9007687105975,"d":"26.90"},{"v":0.673786079484485,"d":"0.67"},{"v":-0.569637472402993,"d":"-0.57"},{"v":0.407457234728668,"d":"0.41"},1,"down","no"]
["MSTRG.13735","POR","ENST00000394893;ENST00000461988;ENST00000493973;ENST00000495770;ENST00000487247;ENST00000418341;ENST00000414186;ENST00000453773;ENST00000448410;ENST00000475509;ENST00000432753;ENST00000496888;ENST00000412521;ENST00000449920;ENST00000471238;ENST00000412064;ENST00000439269;ENST00000439963;ENST00000460892;ENST00000421059","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005515(protein binding);GO:0010181(FMN binding);GO:0043231(intracellular membrane-bounded organelle);GO:0006805(xenobiotic metabolic process);GO:0003958(NADPH-hemoprotein reductase activity);GO:0032770(positive regulation of monooxygenase activity);GO:0090346(cellular organofluorine metabolic process);GO:0004128(cytochrome-b5 reductase activity, acting on NAD(P)H);GO:0008941(nitric oxide dioxygenase activity);GO:0009055(electron carrier activity);GO:0016787(hydrolase activity);GO:0019899(enzyme binding);GO:0047726(iron-cytochrome-c reductase activity);GO:0050660(flavin adenine dinucleotide binding);GO:0050661(NADP binding);GO:0003420(regulation of growth plate cartilage chondrocyte proliferation);GO:0007584(response to nutrient);GO:0009437(carnitine metabolic process);GO:0009812(flavonoid metabolic process);GO:0018393(internal peptidyl-lysine acetylation);GO:0019395(fatty acid oxidation);GO:0032332(positive regulation of chondrocyte differentiation);GO:0042493(response to drug);GO:0043066(negative regulation of apoptotic process);GO:0043154(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process);GO:0043602(nitrate catabolic process);GO:0045542(positive regulation of cholesterol biosynthetic process);GO:0045880(positive regulation of smoothened signaling pathway);GO:0046210(nitric oxide catabolic process);GO:0060192(negative regulation of lipase activity);GO:0070988(demethylation);GO:0071371(cellular response to gonadotropin stimulus);GO:0071372(cellular response to follicle-stimulating hormone stimulus);GO:0071375(cellular response to peptide hormone stimulus);GO:0090031(positive regulation of steroid hormone biosynthetic process);GO:0090181(regulation of cholesterol metabolic process);GO:0005739(mitochondrion);GO:0005739(mitochondrion)","NA","NA","NA","cytochrome p450 oxidoreductase [Source:HGNC Symbol;Acc:HGNC:9208]",{"v":5.1810006822644,"d":"5.18"},{"v":7.6987798684555,"d":"7.70"},{"v":0.672963868403708,"d":"0.67"},{"v":-0.571399046625496,"d":"-0.57"},{"v":0.40980546012243,"d":"0.41"},1,"down","no"]
["MSTRG.2471","POLR2G","ENST00000301788;ENST00000533442;ENST00000527435;ENST00000531944;ENST00000526368;ENST00000531996;ENST00000525455;ENST00000524819","GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0006351(transcription, DNA-templated);GO:0003899(DNA-directed 5'-3' RNA polymerase activity);GO:0006366(transcription from RNA polymerase II promoter);GO:0031369(translation initiation factor binding);GO:0000932(P-body);GO:0003697(single-stranded DNA binding);GO:0003727(single-stranded RNA binding);GO:0006368(transcription elongation from RNA polymerase II promoter);GO:0006370(7-methylguanosine mRNA capping);GO:0050434(positive regulation of viral transcription);GO:0006367(transcription initiation from RNA polymerase II promoter);GO:0042795(snRNA transcription from RNA polymerase II promoter);GO:0000398(mRNA splicing, via spliceosome);GO:0060964(regulation of gene silencing by miRNA);GO:0006283(transcription-coupled nucleotide-excision repair);GO:0008543(fibroblast growth factor receptor signaling pathway);GO:0016070(RNA metabolic process);GO:0035019(somatic stem cell population maintenance);GO:0045948(positive regulation of translational initiation);GO:0005665(DNA-directed RNA polymerase II, core complex);GO:0000291(nuclear-transcribed mRNA catabolic process, exonucleolytic);GO:0006915(apoptotic process);GO:0060213(positive regulation of nuclear-transcribed mRNA poly(A) tail shortening);GO:0060213(positive regulation of nuclear-transcribed mRNA poly(A) tail shortening)","00230(Purine metabolism);00240(Pyrimidine metabolism);03020(RNA polymerase);05016(Huntington's disease);05169(Epstein-Barr virus infection);05169(Epstein-Barr virus infection)","K03015","NA","RNA polymerase II subunit G [Source:HGNC Symbol;Acc:HGNC:9194]",{"v":3.76022465366615,"d":"3.76"},{"v":5.59743036297452,"d":"5.60"},{"v":0.671776942244608,"d":"0.67"},{"v":-0.573945816850293,"d":"-0.57"},{"v":0.410659671395918,"d":"0.41"},1,"down","no"]
["MSTRG.10954","MANF","ENST00000470900;ENST00000528157;ENST00000446668;ENST00000482262","GO:0005615(extracellular space);GO:0005783(endoplasmic reticulum);GO:0048471(perinuclear region of cytoplasm);GO:0048471(perinuclear region of cytoplasm)","NA","NA","NA","mesencephalic astrocyte derived neurotrophic factor [Source:HGNC Symbol;Acc:HGNC:15461]",{"v":14.800926397442,"d":"14.80"},{"v":10.3725394827096,"d":"10.37"},{"v":1.42693372458251,"d":"1.43"},{"v":0.512918328901568,"d":"0.51"},{"v":0.412095615969462,"d":"0.41"},1,"up","no"]
["MSTRG.9787","PLTP","ENST00000354050;ENST00000477313;ENST00000372420","GO:0006810(transport);GO:0005615(extracellular space);GO:0006629(lipid metabolic process);GO:0008289(lipid binding);GO:0005576(extracellular region);GO:0006869(lipid transport);GO:0010875(positive regulation of cholesterol efflux);GO:0034375(high-density lipoprotein particle remodeling);GO:0010189(vitamin E biosynthetic process);GO:0030317(flagellated sperm motility);GO:0030317(flagellated sperm motility)","03320(PPAR signaling pathway);04979(Cholesterol metabolism);04979(Cholesterol metabolism)","K08761","NA","phospholipid transfer protein [Source:HGNC Symbol;Acc:HGNC:9093]",{"v":0.40156158480913,"d":"0.40"},{"v":0.271037229830775,"d":"0.27"},{"v":1.4815735279609,"d":"1.48"},{"v":0.567130226563971,"d":"0.57"},{"v":0.413964427377904,"d":"0.41"},1,"up","no"]
["MSTRG.9542","PSMF1;C20orf202","ENST00000335877;ENST00000246015;ENST00000484891;ENST00000381899;ENST00000400633;ENST00000479715;ENST00000435720;ENST00000381898;ENST00000333082;ENST00000418246;ENST00000478004","GO:0005829(cytosol);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0010951(negative regulation of endopeptidase activity);GO:0005783(endoplasmic reticulum);GO:0005515(protein binding);GO:0000502(proteasome complex);GO:0006511(ubiquitin-dependent protein catabolic process);GO:0038095(Fc-epsilon receptor signaling pathway);GO:0005654(nucleoplasm);GO:0000165(MAPK cascade);GO:0000209(protein polyubiquitination);GO:0002223(stimulatory C-type lectin receptor signaling pathway);GO:0002479(antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent);GO:0006521(regulation of cellular amino acid metabolic process);GO:0010972(negative regulation of G2/M transition of mitotic cell cycle);GO:0016579(protein deubiquitination);GO:0031145(anaphase-promoting complex-dependent catabolic process);GO:0031146(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process);GO:0033209(tumor necrosis factor-mediated signaling pathway);GO:0038061(NIK/NF-kappaB signaling);GO:0043161(proteasome-mediated ubiquitin-dependent protein catabolic process);GO:0043488(regulation of mRNA stability);GO:0043687(post-translational protein modification);GO:0050852(T cell receptor signaling pathway);GO:0051437(positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition);GO:0055085(transmembrane transport);GO:0060071(Wnt signaling pathway, planar cell polarity pathway);GO:0061418(regulation of transcription from RNA polymerase II promoter in response to hypoxia);GO:0090090(negative regulation of canonical Wnt signaling pathway);GO:0090263(positive regulation of canonical Wnt signaling pathway);GO:1902036(regulation of hematopoietic stem cell differentiation);GO:0051436(negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle);GO:0042803(protein homodimerization activity);GO:0046982(protein heterodimerization activity);GO:0048471(perinuclear region of cytoplasm);GO:0070628(proteasome binding);GO:0005839(proteasome core complex);GO:0004866(endopeptidase inhibitor activity);GO:1901799(negative regulation of proteasomal protein catabolic process);GO:1901799(negative regulation of proteasomal protein catabolic process)","03050(Proteasome);03050(Proteasome)","K06700","NA","proteasome inhibitor subunit 1 [Source:HGNC Symbol;Acc:HGNC:9571];chromosome 20 open reading frame 202 [Source:HGNC Symbol;Acc:HGNC:37254]",{"v":32.3355137011752,"d":"32.34"},{"v":22.7233931170957,"d":"22.72"},{"v":1.42300551394536,"d":"1.42"},{"v":0.508941252114721,"d":"0.51"},{"v":0.414400941084259,"d":"0.41"},1,"up","no"]
["MSTRG.2412","OSBP","ENST00000263847;ENST00000528903;ENST00000525357","GO:0006810(transport);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005794(Golgi apparatus);GO:0005634(nucleus);GO:0005730(nucleolus);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0030054(cell junction);GO:0005515(protein binding);GO:0000139(Golgi membrane);GO:0048471(perinuclear region of cytoplasm);GO:0006869(lipid transport);GO:0008289(lipid binding);GO:0019904(protein domain specific binding);GO:0006699(bile acid biosynthetic process);GO:0070273(phosphatidylinositol-4-phosphate binding);GO:0008142(oxysterol binding);GO:0015248(sterol transporter activity);GO:0015918(sterol transport);GO:0044128(positive regulation of growth of symbiont in host);GO:0044128(positive regulation of growth of symbiont in host)","NA","NA","NA","oxysterol binding protein [Source:HGNC Symbol;Acc:HGNC:8503]",{"v":7.27084786616897,"d":"7.27"},{"v":5.11436860360524,"d":"5.11"},{"v":1.42165112249508,"d":"1.42"},{"v":0.507567466645247,"d":"0.51"},{"v":0.415927776049076,"d":"0.42"},1,"up","no"]
["MSTRG.11678","SERBP1P5","ENST00000510079","NA","NA","NA","NA","SERPINE1 mRNA binding protein 1 pseudogene 5 [Source:HGNC Symbol;Acc:HGNC:44632]",{"v":2.482546,"d":"2.48"},{"v":1.72477,"d":"1.72"},{"v":1.43934901465123,"d":"1.44"},{"v":0.525416460496829,"d":"0.53"},{"v":0.416239681342811,"d":"0.42"},1,"up","no"]
["MSTRG.13274","SAMD3;AL355581.1","ENST00000533296;ENST00000532763;MSTRG.13274.1;ENST00000437477;ENST00000439090;ENST00000457563;ENST00000529119;ENST00000528422;ENST00000591297;ENST00000415964;MSTRG.13274.8;ENST00000324172;ENST00000524930;ENST00000531544;ENST00000609978;ENST00000532309;ENST00000526886;ENST00000614735","GO:0005515(protein binding);GO:0005515(protein binding)","NA","NA","NA","sterile alpha motif domain containing 3 [Source:HGNC Symbol;Acc:HGNC:21574]",{"v":3.17423783340517,"d":"3.17"},{"v":2.23252889547414,"d":"2.23"},{"v":1.42181265373098,"d":"1.42"},{"v":0.507731379627138,"d":"0.51"},{"v":0.417549275704442,"d":"0.42"},1,"up","no"]
["ENSG00000046647","GEMIN8","ENST00000380523;ENST00000398355;ENST00000477386;ENST00000460203;ENST00000332885","GO:0006397(mRNA processing);GO:0008380(RNA splicing);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0000387(spliceosomal snRNP assembly);GO:0032797(SMN complex);GO:0005515(protein binding);GO:0005654(nucleoplasm);GO:0051170(nuclear import);GO:0034719(SMN-Sm protein complex);GO:0097504(Gemini of coiled bodies);GO:0097504(Gemini of coiled bodies)","03013(RNA transport);03013(RNA transport)","K13136","NA","gem nuclear organelle associated protein 8 [Source:HGNC Symbol;Acc:HGNC:26044]",{"v":0.933241938118812,"d":"0.93"},{"v":0.649754781353135,"d":"0.65"},{"v":1.43629868513673,"d":"1.44"},{"v":0.522355795649397,"d":"0.52"},{"v":0.419271101702193,"d":"0.42"},1,"up","no"]
["MSTRG.6841","TUBG1","ENST00000251413;ENST00000588056;ENST00000589688;ENST00000589613","GO:0003924(GTPase activity);GO:0005874(microtubule);GO:0007017(microtubule-based process);GO:0007020(microtubule nucleation);GO:0031122(cytoplasmic microtubule organization);GO:0000930(gamma-tubulin complex);GO:0005525(GTP binding);GO:0000166(nucleotide binding);GO:0005737(cytoplasm);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0005813(centrosome);GO:0005815(microtubule organizing center);GO:0005829(cytosol);GO:0055037(recycling endosome);GO:0000086(G2/M transition of mitotic cell cycle);GO:0010389(regulation of G2/M transition of mitotic cell cycle);GO:0097711(ciliary basal body docking);GO:0005200(structural constituent of cytoskeleton);GO:0000794(condensed nuclear chromosome);GO:0000226(microtubule cytoskeleton organization);GO:0000212(meiotic spindle organization);GO:0000242(pericentriolar material);GO:0005814(centriole);GO:0005827(polar microtubule);GO:0005876(spindle microtubule);GO:0005881(cytoplasmic microtubule);GO:0005929(cilium);GO:0031252(cell leading edge);GO:0036064(ciliary basal body);GO:0045177(apical part of cell);GO:0097730(non-motile cilium);GO:0097730(non-motile cilium)","05165(Human papillomavirus infection);05165(Human papillomavirus infection)","K10389","NA","tubulin gamma 1 [Source:HGNC Symbol;Acc:HGNC:12417]",{"v":3.77881487225218,"d":"3.78"},{"v":2.66767835338034,"d":"2.67"},{"v":1.41651817486312,"d":"1.42"},{"v":0.502349112564356,"d":"0.50"},{"v":0.420046517860908,"d":"0.42"},1,"up","no"]
["ENSG00000158555","GDPD5","ENST00000531759;ENST00000529095;ENST00000531561;ENST00000526177;ENST00000534322;ENST00000531441;ENST00000527820;ENST00000528031;ENST00000533911;ENST00000336898;ENST00000529721;ENST00000532435;ENST00000533805","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016787(hydrolase activity);GO:0006629(lipid metabolic process);GO:0042995(cell projection);GO:0005515(protein binding);GO:0048471(perinuclear region of cytoplasm);GO:0007399(nervous system development);GO:0008081(phosphoric diester hydrolase activity);GO:0030426(growth cone);GO:0012505(endomembrane system);GO:0008889(glycerophosphodiester phosphodiesterase activity);GO:0047389(glycerophosphocholine phosphodiesterase activity);GO:0021522(spinal cord motor neuron differentiation);GO:0021895(cerebral cortex neuron differentiation);GO:0031175(neuron projection development);GO:0045666(positive regulation of neuron differentiation);GO:0045746(negative regulation of Notch signaling pathway);GO:0045787(positive regulation of cell cycle);GO:0048505(regulation of timing of cell differentiation);GO:0030424(axon);GO:0043025(neuronal cell body);GO:0097038(perinuclear endoplasmic reticulum);GO:0097038(perinuclear endoplasmic reticulum)","NA","NA","NA","glycerophosphodiester phosphodiesterase domain containing 5 [Source:HGNC Symbol;Acc:HGNC:28804]",{"v":0.958274500354718,"d":"0.96"},{"v":0.670000156379852,"d":"0.67"},{"v":1.43026011446396,"d":"1.43"},{"v":0.516277546808742,"d":"0.52"},{"v":0.420499448787956,"d":"0.42"},1,"up","no"]
["MSTRG.8111","RYR1","ENST00000355481;ENST00000601514;ENST00000593677","GO:0006810(transport);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0055085(transmembrane transport);GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0005216(ion channel activity);GO:0006811(ion transport);GO:0005509(calcium ion binding);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0006816(calcium ion transport);GO:0070588(calcium ion transmembrane transport);GO:0007275(multicellular organism development);GO:0005262(calcium channel activity);GO:0005219(ryanodine-sensitive calcium-release channel activity);GO:0006874(cellular calcium ion homeostasis);GO:0005516(calmodulin binding);GO:0006936(muscle contraction);GO:0070062(extracellular exosome);GO:0034220(ion transmembrane transport);GO:0016529(sarcoplasmic reticulum);GO:0005938(cell cortex);GO:0031301(integral component of organelle membrane);GO:0005887(integral component of plasma membrane);GO:0031674(I band);GO:0015278(calcium-release channel activity);GO:1903779(regulation of cardiac conduction);GO:0005245(voltage-gated calcium channel activity);GO:0051289(protein homotetramerization);GO:0003151(outflow tract morphogenesis);GO:0051209(release of sequestered calcium ion into cytosol);GO:0033017(sarcoplasmic reticulum membrane);GO:0014701(junctional sarcoplasmic reticulum membrane);GO:0071277(cellular response to calcium ion);GO:0014808(release of sequestered calcium ion into cytosol by sarcoplasmic reticulum);GO:0051480(regulation of cytosolic calcium ion concentration);GO:0043588(skin development);GO:0001666(response to hypoxia);GO:0048763(calcium-induced calcium release activity);GO:0031000(response to caffeine);GO:0043931(ossification involved in bone maturation);GO:0048741(skeletal muscle fiber development);GO:0071313(cellular response to caffeine);GO:0005790(smooth endoplasmic reticulum);GO:0014802(terminal cisterna);GO:1990425(ryanodine receptor complex);GO:0002020(protease binding);GO:0019899(enzyme binding);GO:0030314(junctional membrane complex);GO:0030315(T-tubule);GO:0043234(protein complex);GO:0005623(cell);GO:0005623(cell)","04371(Apelin signaling pathway);04020(Calcium signaling pathway);04921(Oxytocin signaling pathway);04730(Long-term depression);04713(Circadian entrainment);04713(Circadian entrainment)","K04961","NA","ryanodine receptor 1 [Source:HGNC Symbol;Acc:HGNC:10483]",{"v":0.152564035327278,"d":"0.15"},{"v":0.106974413091137,"d":"0.11"},{"v":1.42617314663181,"d":"1.43"},{"v":0.512149144911474,"d":"0.51"},{"v":0.421878931723524,"d":"0.42"},1,"up","no"]
["MSTRG.2904","BCL9L","MSTRG.2904.1;ENST00000334801;ENST00000527266;ENST00000532899;ENST00000530293;ENST00000526143","GO:0010718(positive regulation of epithelial to mesenchymal transition);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0030512(negative regulation of transforming growth factor beta receptor signaling pathway);GO:0005634(nucleus);GO:0005730(nucleolus);GO:0005654(nucleoplasm);GO:0003713(transcription coactivator activity);GO:0008013(beta-catenin binding);GO:0060070(canonical Wnt signaling pathway);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:1904837(beta-catenin-TCF complex assembly);GO:0022604(regulation of cell morphogenesis);GO:0035019(somatic stem cell population maintenance);GO:0035914(skeletal muscle cell differentiation);GO:1903506(regulation of nucleic acid-templated transcription);GO:1903506(regulation of nucleic acid-templated transcription)","NA","NA","NA","B-cell CLL/lymphoma 9 like [Source:HGNC Symbol;Acc:HGNC:23688]",{"v":10.2027810428394,"d":"10.20"},{"v":7.21841036294247,"d":"7.22"},{"v":1.41343876696425,"d":"1.41"},{"v":0.499209384045969,"d":"0.50"},{"v":0.422654619918987,"d":"0.42"},1,"up","no"]
["ENSG00000109685","NSD2","ENST00000508803;ENST00000482415;ENST00000507820;ENST00000436793;ENST00000382888;ENST00000508355;ENST00000513726;ENST00000509115;ENST00000312087;ENST00000398261;ENST00000505643;ENST00000511904;ENST00000508299;ENST00000503207;ENST00000503128;ENST00000420906;ENST00000512700;ENST00000515695;ENST00000514045","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0008168(methyltransferase activity);GO:0016740(transferase activity);GO:0032259(methylation);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0016569(covalent chromatin modification);GO:0003677(DNA binding);GO:0005694(chromosome);GO:0005515(protein binding);GO:0018024(histone-lysine N-methyltransferase activity);GO:0005654(nucleoplasm);GO:0009653(anatomical structure morphogenesis);GO:0006303(double-strand break repair via nonhomologous end joining);GO:0042799(histone methyltransferase activity (H4-K20 specific));GO:0003682(chromatin binding);GO:0043565(sequence-specific DNA binding);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0003149(membranous septum morphogenesis);GO:0003289(atrial septum primum morphogenesis);GO:0003290(atrial septum secundum morphogenesis);GO:0010452(histone H3-K36 methylation);GO:0034770(histone H4-K20 methylation);GO:0048298(positive regulation of isotype switching to IgA isotypes);GO:0060348(bone development);GO:0070201(regulation of establishment of protein localization);GO:2001032(regulation of double-strand break repair via nonhomologous end joining);GO:2001032(regulation of double-strand break repair via nonhomologous end joining)","00310(Lysine degradation);05202(Transcriptional misregulation in cancers);05202(Transcriptional misregulation in cancers)","K11424","EC:2.1.1.43","nuclear receptor binding SET domain protein 2 [Source:HGNC Symbol;Acc:HGNC:12766]",{"v":0.726008823776294,"d":"0.73"},{"v":0.511440544498382,"d":"0.51"},{"v":1.41953709299359,"d":"1.42"},{"v":0.505420547673601,"d":"0.51"},{"v":0.423384010772342,"d":"0.42"},1,"up","no"]
["MSTRG.5369","WHAMM","ENST00000286760;ENST00000560964","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005829(cytosol);GO:0003779(actin binding);GO:0005794(Golgi apparatus);GO:0000139(Golgi membrane);GO:0005874(microtubule);GO:0030659(cytoplasmic vesicle membrane);GO:0031410(cytoplasmic vesicle);GO:0008017(microtubule binding);GO:0006888(ER to Golgi vesicle-mediated transport);GO:0030032(lamellipodium assembly);GO:0048041(focal adhesion assembly);GO:0017049(GTP-Rho binding);GO:0007015(actin filament organization);GO:0005793(endoplasmic reticulum-Golgi intermediate compartment);GO:0033116(endoplasmic reticulum-Golgi intermediate compartment membrane);GO:0097320(plasma membrane tubulation);GO:0051127(positive regulation of actin nucleation);GO:0090527(actin filament reorganization);GO:0071933(Arp2/3 complex binding);GO:0007050(cell cycle arrest);GO:0034314(Arp2/3 complex-mediated actin nucleation);GO:0034314(Arp2/3 complex-mediated actin nucleation)","04530(Tight junction);04530(Tight junction)","K20479","NA","WAS protein homolog associated with actin, golgi membranes and microtubules [Source:HGNC Symbol;Acc:HGNC:30493]",{"v":2.79436492367753,"d":"2.79"},{"v":1.97480438297872,"d":"1.97"},{"v":1.41500846755394,"d":"1.42"},{"v":0.500810686316191,"d":"0.50"},{"v":0.425299054006515,"d":"0.43"},1,"up","no"]
["MSTRG.8744","USP34","ENST00000490552;ENST00000398571;ENST00000498268;ENST00000494867;ENST00000453734;ENST00000492882;ENST00000411912;ENST00000468703;ENST00000463046;ENST00000467128;ENST00000453133;ENST00000483672;ENST00000482250;ENST00000490527;ENST00000492604;ENST00000472689;ENST00000487547","GO:0016579(protein deubiquitination);GO:0016787(hydrolase activity);GO:0008233(peptidase activity);GO:0008234(cysteine-type peptidase activity);GO:0006508(proteolysis);GO:0006511(ubiquitin-dependent protein catabolic process);GO:0036459(thiol-dependent ubiquitinyl hydrolase activity);GO:0016055(Wnt signaling pathway);GO:0005515(protein binding);GO:0005829(cytosol);GO:0004843(thiol-dependent ubiquitin-specific protease activity);GO:0071108(protein K48-linked deubiquitination);GO:0090263(positive regulation of canonical Wnt signaling pathway);GO:0004197(cysteine-type endopeptidase activity);GO:0004197(cysteine-type endopeptidase activity)","NA","NA","NA","ubiquitin specific peptidase 34 [Source:HGNC Symbol;Acc:HGNC:20066]",{"v":3.26678588507586,"d":"3.27"},{"v":4.77613697991724,"d":"4.78"},{"v":0.683980777522103,"d":"0.68"},{"v":-0.547972314459263,"d":"-0.55"},{"v":0.427021689828819,"d":"0.43"},1,"down","no"]
["ENSG00000283199","FP565324.1","ENST00000636427;ENST00000637024","NA","NA","NA","NA",null,{"v":0.763181898273071,"d":"0.76"},{"v":0.53634068267674,"d":"0.54"},{"v":1.42294240008836,"d":"1.42"},{"v":0.508877263558875,"d":"0.51"},{"v":0.427792177765136,"d":"0.43"},1,"up","no"]
["MSTRG.2549","FAM89B;SSSCA1","ENST00000449319;ENST00000316409;ENST00000530349;ENST00000526433;ENST00000531405;ENST00000309328;ENST00000527413;ENST00000527920","GO:0005737(cytoplasm);GO:0009986(cell surface);GO:0030512(negative regulation of transforming growth factor beta receptor signaling pathway);GO:0001222(transcription corepressor binding);GO:0060392(negative regulation of SMAD protein import into nucleus);GO:0051301(cell division);GO:0005515(protein binding);GO:0007049(cell cycle);GO:0000278(mitotic cell cycle);GO:0042802(identical protein binding);GO:0042802(identical protein binding)","NA","NA","NA","family with sequence similarity 89 member B [Source:HGNC Symbol;Acc:HGNC:16708];Sjogren syndrome/scleroderma autoantigen 1 [Source:HGNC Symbol;Acc:HGNC:11328]",{"v":9.62124393842364,"d":"9.62"},{"v":14.0676121925287,"d":"14.07"},{"v":0.683928715602032,"d":"0.68"},{"v":-0.548082130897147,"d":"-0.55"},{"v":0.429433721533891,"d":"0.43"},1,"down","no"]
["MSTRG.4885","SLC12A6","ENST00000397707;ENST00000559664;ENST00000560611;ENST00000290209;ENST00000559236;ENST00000559076;ENST00000560164;ENST00000558950;ENST00000558667;ENST00000560023;ENST00000561080;ENST00000559441","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005215(transporter activity);GO:0055085(transmembrane transport);GO:0006811(ion transport);GO:0005887(integral component of plasma membrane);GO:0015293(symporter activity);GO:0006813(potassium ion transport);GO:0005886(plasma membrane);GO:0071805(potassium ion transmembrane transport);GO:0015377(cation:chloride symporter activity);GO:0015379(potassium:chloride symporter activity);GO:0071477(cellular hypotonic salinity response);GO:1902476(chloride transmembrane transport);GO:0022820(potassium ion symporter activity);GO:0016323(basolateral plasma membrane);GO:0007268(chemical synaptic transmission);GO:0001525(angiogenesis);GO:0001525(angiogenesis)","NA","NA","NA","solute carrier family 12 member 6 [Source:HGNC Symbol;Acc:HGNC:10914]",{"v":5.70923633442721,"d":"5.71"},{"v":8.3296811676611,"d":"8.33"},{"v":0.68540874728706,"d":"0.69"},{"v":-0.544963491026868,"d":"-0.54"},{"v":0.430250502115729,"d":"0.43"},1,"down","no"]
["MSTRG.11033","PSMD6-AS2","ENST00000472046","NA","NA","NA","NA","PSMD6 antisense RNA 2 [Source:HGNC Symbol;Acc:HGNC:44125]",{"v":0.559615897799858,"d":"0.56"},{"v":0.831389118523776,"d":"0.83"},{"v":0.673109480664744,"d":"0.67"},{"v":-0.571086917887706,"d":"-0.57"},{"v":0.431429238982145,"d":"0.43"},1,"down","no"]
["MSTRG.5841","SEPT1;AC116348.4","ENST00000573615;ENST00000563743;ENST00000321367;ENST00000563957;ENST00000568577;ENST00000566517;ENST00000562152;ENST00000570039;ENST00000624127;ENST00000572252;ENST00000567783","GO:0005525(GTP binding);GO:0000166(nucleotide binding);GO:0007056(spindle assembly involved in female meiosis);GO:0051311(meiotic metaphase plate congression);GO:0030496(midbody);GO:0072687(meiotic spindle);GO:0072687(meiotic spindle)","05100(Bacterial invasion of epithelial cells);05100(Bacterial invasion of epithelial cells)","K13737","NA","septin 1 [Source:HGNC Symbol;Acc:HGNC:2879]",{"v":10.0218328990521,"d":"10.02"},{"v":7.14073155379147,"d":"7.14"},{"v":1.40347425520161,"d":"1.40"},{"v":0.489002599843579,"d":"0.49"},{"v":0.433048864779899,"d":"0.43"},1,"up","no"]
["MSTRG.1346","RASSF5","ENST00000579942;ENST00000577571;ENST00000605653;ENST00000636182;ENST00000581503;ENST00000581888;ENST00000580449;ENST00000605120;ENST00000579436","GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0035556(intracellular signal transduction);GO:0007165(signal transduction);GO:0042981(regulation of apoptotic process);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0006915(apoptotic process);GO:0005874(microtubule);GO:0017016(Ras GTPase binding);GO:0008285(negative regulation of cell proliferation);GO:0031398(positive regulation of protein ubiquitination);GO:1900180(regulation of protein localization to nucleus);GO:0005634(nucleus);GO:0005622(intracellular);GO:0005622(intracellular)","04014(Ras signaling pathway);04015(Rap1 signaling pathway);04218(Cellular senescence);04670(Leukocyte transendothelial migration);05200(Pathways in cancer);05223(Non-small cell lung cancer);05223(Non-small cell lung cancer)","K08015","NA","Ras association domain family member 5 [Source:HGNC Symbol;Acc:HGNC:17609]",{"v":10.224479590453,"d":"10.22"},{"v":14.8545096129587,"d":"14.85"},{"v":0.68830812035245,"d":"0.69"},{"v":-0.538873564561211,"d":"-0.54"},{"v":0.434605397566534,"d":"0.43"},1,"down","no"]
["MSTRG.5351","ZFAND6","ENST00000561060;ENST00000558494;ENST00000557983;ENST00000261749;ENST00000558087;ENST00000558997;ENST00000561017;ENST00000558390;ENST00000560976;ENST00000560470;ENST00000558688;ENST00000559775;ENST00000559157;ENST00000558724;ENST00000557793;ENST00000560392;ENST00000559835;ENST00000618205;ENST00000558272;ENST00000561012;ENST00000613266;ENST00000616533","GO:0006810(transport);GO:0005737(cytoplasm);GO:0015031(protein transport);GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0006915(apoptotic process);GO:0003674(molecular_function);GO:0005575(cellular_component);GO:0071356(cellular response to tumor necrosis factor);GO:0043066(negative regulation of apoptotic process);GO:0006625(protein targeting to peroxisome);GO:0043122(regulation of I-kappaB kinase/NF-kappaB signaling);GO:0031593(polyubiquitin binding);GO:0031593(polyubiquitin binding)","NA","NA","NA","zinc finger AN1-type containing 6 [Source:HGNC Symbol;Acc:HGNC:30164]",{"v":2.94297737667378,"d":"2.94"},{"v":4.28372526334174,"d":"4.28"},{"v":0.687013567807091,"d":"0.69"},{"v":-0.541589503828383,"d":"-0.54"},{"v":0.435888733313594,"d":"0.44"},1,"down","no"]
["ENSG00000175711","B3GNTL1","ENST00000572977;ENST00000576599;ENST00000571301;ENST00000320865;ENST00000572267;ENST00000571394;ENST00000571954;ENST00000573363;ENST00000571218","GO:0016740(transferase activity);GO:0016757(transferase activity, transferring glycosyl groups);GO:0016757(transferase activity, transferring glycosyl groups)","NA","NA","NA","UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase like 1 [Source:HGNC Symbol;Acc:HGNC:21727]",{"v":0.478510530401974,"d":"0.48"},{"v":0.695832124655347,"d":"0.70"},{"v":0.687680998687701,"d":"0.69"},{"v":-0.540188611847401,"d":"-0.54"},{"v":0.435959999616039,"d":"0.44"},1,"down","no"]
["ENSG00000182985","CADM1","ENST00000452722;ENST00000541434;ENST00000546000;ENST00000545094;ENST00000540951;ENST00000441886;ENST00000612235","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0007155(cell adhesion);GO:0042803(protein homodimerization activity);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0006915(apoptotic process);GO:0007275(multicellular organism development);GO:0030054(cell junction);GO:0045202(synapse);GO:0030154(cell differentiation);GO:0002376(immune system process);GO:0007283(spermatogenesis);GO:0005887(integral component of plasma membrane);GO:0070062(extracellular exosome);GO:0016323(basolateral plasma membrane);GO:0005102(receptor binding);GO:0005911(cell-cell junction);GO:0007156(homophilic cell adhesion via plasma membrane adhesion molecules);GO:0030165(PDZ domain binding);GO:0004872(receptor activity);GO:0050839(cell adhesion molecule binding);GO:0007157(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules);GO:0005913(cell-cell adherens junction);GO:0008037(cell recognition);GO:0045954(positive regulation of natural killer cell mediated cytotoxicity);GO:0034332(adherens junction organization);GO:0050715(positive regulation of cytokine secretion);GO:0042271(susceptibility to natural killer cell mediated cytotoxicity);GO:0051606(detection of stimulus);GO:0051606(detection of stimulus)","04514(Cell adhesion molecules (CAMs));04514(Cell adhesion molecules (CAMs))","K06781","NA","cell adhesion molecule 1 [Source:HGNC Symbol;Acc:HGNC:5951]",{"v":0.0999855197422166,"d":"0.10"},{"v":0.150015371425978,"d":"0.15"},{"v":0.666501831057709,"d":"0.67"},{"v":-0.585319256100875,"d":"-0.59"},{"v":0.437552599326989,"d":"0.44"},1,"down","no"]
["MSTRG.10386","PIK3IP1","ENST00000441972;ENST00000493034;ENST00000480654;ENST00000215912;ENST00000402249;ENST00000443175","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0014067(negative regulation of phosphatidylinositol 3-kinase signaling);GO:0043553(negative regulation of phosphatidylinositol 3-kinase activity);GO:0070062(extracellular exosome);GO:0036313(phosphatidylinositol 3-kinase catalytic subunit binding);GO:0036313(phosphatidylinositol 3-kinase catalytic subunit binding)","NA","NA","NA","phosphoinositide-3-kinase interacting protein 1 [Source:HGNC Symbol;Acc:HGNC:24942]",{"v":28.2236616236531,"d":"28.22"},{"v":20.2131318241787,"d":"20.21"},{"v":1.39630324826222,"d":"1.40"},{"v":0.481612299178797,"d":"0.48"},{"v":0.438561692711513,"d":"0.44"},1,"up","no"]
["ENSG00000124608","AARS2","ENST00000244571;ENST00000491573","GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0005737(cytoplasm);GO:0006412(translation);GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0005739(mitochondrion);GO:0016874(ligase activity);GO:0004812(aminoacyl-tRNA ligase activity);GO:0000049(tRNA binding);GO:0016876(ligase activity, forming aminoacyl-tRNA and related compounds);GO:0043039(tRNA aminoacylation);GO:0004813(alanine-tRNA ligase activity);GO:0006419(alanyl-tRNA aminoacylation);GO:0016597(amino acid binding);GO:0006400(tRNA modification);GO:0033108(mitochondrial respiratory chain complex assembly);GO:0070143(mitochondrial alanyl-tRNA aminoacylation);GO:0070143(mitochondrial alanyl-tRNA aminoacylation)","00970(Aminoacyl-tRNA biosynthesis);00970(Aminoacyl-tRNA biosynthesis)","K01872","EC:6.1.1.7","alanyl-tRNA synthetase 2, mitochondrial [Source:HGNC Symbol;Acc:HGNC:21022]",{"v":1.81588422242904,"d":"1.82"},{"v":1.29742157142857,"d":"1.30"},{"v":1.39961001298105,"d":"1.40"},{"v":0.485024890943928,"d":"0.49"},{"v":0.439515897075331,"d":"0.44"},1,"up","no"]
["MSTRG.12192","RHOBTB3","ENST00000379982;ENST00000514198;ENST00000504949;ENST00000511558;ENST00000510313;ENST00000512878;ENST00000513091;ENST00000506817","GO:0005525(GTP binding);GO:0003924(GTPase activity);GO:0006810(transport);GO:0016192(vesicle-mediated transport);GO:0005829(cytosol);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0016787(hydrolase activity);GO:0005794(Golgi apparatus);GO:0005515(protein binding);GO:0017137(Rab GTPase binding);GO:0016887(ATPase activity);GO:0070062(extracellular exosome);GO:0042147(retrograde transport, endosome to Golgi);GO:0032588(trans-Golgi network membrane);GO:0008584(male gonad development);GO:0005737(cytoplasm);GO:0005737(cytoplasm)","NA","NA","NA","Rho related BTB domain containing 3 [Source:HGNC Symbol;Acc:HGNC:18757]",{"v":0.209989173553719,"d":"0.21"},{"v":0.149100725008491,"d":"0.15"},{"v":1.40837124394774,"d":"1.41"},{"v":0.49402767574061,"d":"0.49"},{"v":0.440292790635787,"d":"0.44"},1,"up","no"]
["MSTRG.3174","YBX3","MSTRG.3174.7;ENST00000540447;ENST00000546164;ENST00000542002;ENST00000279550;ENST00000228251;ENST00000366290;ENST00000536823;ENST00000542641;ENST00000366286;ENST00000544622;ENST00000536107;ENST00000544504;ENST00000546298;ENST00000544501;ENST00000539204;ENST00000540975;ENST00000541351","GO:0048471(perinuclear region of cytoplasm);GO:0005634(nucleus);GO:0003730(mRNA 3'-UTR binding);GO:0071356(cellular response to tumor necrosis factor);GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0003714(transcription corepressor activity);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0017048(Rho GTPase binding);GO:0071474(cellular hyperosmotic response);GO:1902219(negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress);GO:0060546(negative regulation of necroptotic process);GO:0003690(double-stranded DNA binding);GO:0009409(response to cold);GO:0070935(3'-UTR-mediated mRNA stabilization);GO:2000767(positive regulation of cytoplasmic translation);GO:0005923(bicellular tight junction);GO:0000977(RNA polymerase II regulatory region sequence-specific DNA binding);GO:0001227(transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding);GO:0003697(single-stranded DNA binding);GO:0001701(in utero embryonic development);GO:0007283(spermatogenesis);GO:0008584(male gonad development);GO:0009566(fertilization);GO:0043066(negative regulation of apoptotic process);GO:0046622(positive regulation of organ growth);GO:0048642(negative regulation of skeletal muscle tissue development);GO:0005844(polysome);GO:0030529(intracellular ribonucleoprotein complex);GO:0030529(intracellular ribonucleoprotein complex)","04530(Tight junction);04530(Tight junction)","K06099","NA","Y-box binding protein 3 [Source:HGNC Symbol;Acc:HGNC:2428]",{"v":38.5513510079898,"d":"38.55"},{"v":27.6885296120889,"d":"27.69"},{"v":1.3923220751729,"d":"1.39"},{"v":0.477492977356113,"d":"0.48"},{"v":0.44205438845476,"d":"0.44"},1,"up","no"]
["MSTRG.6513","GRAP","ENST00000284154;ENST00000571380;ENST00000573099;ENST00000583020","GO:0009967(positive regulation of signal transduction);GO:0005515(protein binding);GO:0045087(innate immune response);GO:0005829(cytosol);GO:0030154(cell differentiation);GO:0005737(cytoplasm);GO:0007267(cell-cell signaling);GO:0042127(regulation of cell proliferation);GO:0016477(cell migration);GO:0005070(SH3/SH2 adaptor activity);GO:0007265(Ras protein signal transduction);GO:0005102(receptor binding);GO:0038083(peptidyl-tyrosine autophosphorylation);GO:0031234(extrinsic component of cytoplasmic side of plasma membrane);GO:0004715(non-membrane spanning protein tyrosine kinase activity);GO:0007169(transmembrane receptor protein tyrosine kinase signaling pathway);GO:0007169(transmembrane receptor protein tyrosine kinase signaling pathway)","NA","NA","NA","GRB2-related adaptor protein [Source:HGNC Symbol;Acc:HGNC:4562]",{"v":3.58404341680077,"d":"3.58"},{"v":2.57134023012552,"d":"2.57"},{"v":1.39384254748187,"d":"1.39"},{"v":0.479067599372261,"d":"0.48"},{"v":0.443208002087042,"d":"0.44"},1,"up","no"]
["ENSG00000135249","RINT1","ENST00000257700;ENST00000474123;ENST00000493258;ENST00000477285;ENST00000467392;ENST00000493041;ENST00000482041","GO:1902504(regulation of signal transduction involved in mitotic G2 DNA damage checkpoint);GO:0006810(transport);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0015031(protein transport);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005515(protein binding);GO:0007049(cell cycle);GO:0048193(Golgi vesicle transport);GO:0016192(vesicle-mediated transport);GO:0005829(cytosol);GO:0006890(retrograde vesicle-mediated transport, Golgi to ER);GO:0070939(Dsl1/NZR complex);GO:0060628(regulation of ER to Golgi vesicle-mediated transport);GO:0060628(regulation of ER to Golgi vesicle-mediated transport)","NA","NA","NA","RAD50 interactor 1 [Source:HGNC Symbol;Acc:HGNC:21876]",{"v":1.94305767660739,"d":"1.94"},{"v":1.38657767961696,"d":"1.39"},{"v":1.40133344505023,"d":"1.40"},{"v":0.486800283593261,"d":"0.49"},{"v":0.444270604013802,"d":"0.44"},1,"up","no"]
["ENSG00000070404","FSTL3","ENST00000166139;ENST00000592947;ENST00000589185;ENST00000591573","GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0048185(activin binding);GO:0001822(kidney development);GO:0007283(spermatogenesis);GO:0008584(male gonad development);GO:0030324(lung development);GO:0030325(adrenal gland development);GO:0030514(negative regulation of BMP signaling pathway);GO:0071248(cellular response to metal ion);GO:0005615(extracellular space);GO:0005794(Golgi apparatus);GO:0030141(secretory granule);GO:0044306(neuron projection terminus);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0044267(cellular protein metabolic process);GO:0001968(fibronectin binding);GO:0043687(post-translational protein modification);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0001503(ossification);GO:0045671(negative regulation of osteoclast differentiation);GO:0005788(endoplasmic reticulum lumen);GO:0002244(hematopoietic progenitor cell differentiation);GO:0022409(positive regulation of cell-cell adhesion);GO:0032926(negative regulation of activin receptor signaling pathway);GO:0090101(negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway);GO:0090101(negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway)","NA","NA","NA","follistatin like 3 [Source:HGNC Symbol;Acc:HGNC:3973]",{"v":0.300086732963808,"d":"0.30"},{"v":0.44299376980763,"d":"0.44"},{"v":0.677406215202802,"d":"0.68"},{"v":-0.561906871265912,"d":"-0.56"},{"v":0.446554316642341,"d":"0.45"},1,"down","no"]
["MSTRG.9922","HSPA13","ENST00000285667","GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0005783(endoplasmic reticulum);GO:0005515(protein binding);GO:0043231(intracellular membrane-bounded organelle);GO:0070062(extracellular exosome)","NA","NA","NA","heat shock protein family A (Hsp70) member 13 [Source:HGNC Symbol;Acc:HGNC:11375]",{"v":3.41352429327611,"d":"3.41"},{"v":4.92213310395804,"d":"4.92"},{"v":0.693505076189669,"d":"0.69"},{"v":-0.528021652328594,"d":"-0.53"},{"v":0.447276343995619,"d":"0.45"},1,"down","no"]
["ENSG00000132199","ENOSF1","ENST00000584259;ENST00000579053;ENST00000251101;ENST00000578651;ENST00000340116;ENST00000584706;ENST00000581475;ENST00000583973;ENST00000584646;ENST00000581928;ENST00000383578;ENST00000585004;ENST00000577334;ENST00000578647;ENST00000581906;ENST00000582745;ENST00000580605;ENST00000585128","GO:0046872(metal ion binding);GO:0016853(isomerase activity);GO:0016829(lyase activity);GO:0005739(mitochondrion);GO:0000287(magnesium ion binding);GO:0005575(cellular_component);GO:0050023(L-fuconate dehydratase activity);GO:0009063(cellular amino acid catabolic process);GO:0016052(carbohydrate catabolic process);GO:0044275(cellular carbohydrate catabolic process);GO:0044275(cellular carbohydrate catabolic process)","00051(Fructose and mannose metabolism);00051(Fructose and mannose metabolism)","K18334","EC:4.2.1.68","enolase superfamily member 1 [Source:HGNC Symbol;Acc:HGNC:30365]",{"v":0.423044750470987,"d":"0.42"},{"v":0.300538670026375,"d":"0.30"},{"v":1.40762168952788,"d":"1.41"},{"v":0.493259649331806,"d":"0.49"},{"v":0.44810631263697,"d":"0.45"},1,"up","no"]
["ENSG00000136048","DRAM1","ENST00000258534;ENST00000549365;ENST00000546729;ENST00000549066;ENST00000544152;ENST00000614926","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005765(lysosomal membrane);GO:0005515(protein binding);GO:0006915(apoptotic process);GO:0006914(autophagy);GO:0005764(lysosome);GO:0010506(regulation of autophagy);GO:0010506(regulation of autophagy)","NA","NA","NA","DNA damage regulated autophagy modulator 1 [Source:HGNC Symbol;Acc:HGNC:25645]",{"v":1.69688405454545,"d":"1.70"},{"v":2.44406230956938,"d":"2.44"},{"v":0.694288377142244,"d":"0.69"},{"v":-0.526393074938935,"d":"-0.53"},{"v":0.449686651775938,"d":"0.45"},1,"down","no"]
["ENSG00000134070","IRAK2","ENST00000256458","GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0007165(signal transduction);GO:0005515(protein binding);GO:0006954(inflammatory response);GO:0002755(MyD88-dependent toll-like receptor signaling pathway);GO:0005886(plasma membrane);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0004674(protein serine/threonine kinase activity);GO:0035556(intracellular signal transduction);GO:0005829(cytosol);GO:0010008(endosome membrane);GO:0070498(interleukin-1-mediated signaling pathway);GO:0042803(protein homodimerization activity);GO:0046982(protein heterodimerization activity);GO:0002224(toll-like receptor signaling pathway);GO:0002756(MyD88-independent toll-like receptor signaling pathway);GO:0007249(I-kappaB kinase/NF-kappaB signaling);GO:0051092(positive regulation of NF-kappaB transcription factor activity);GO:0007254(JNK cascade);GO:0070423(nucleotide-binding oligomerization domain containing signaling pathway);GO:0000187(activation of MAPK activity);GO:0001959(regulation of cytokine-mediated signaling pathway);GO:0031663(lipopolysaccharide-mediated signaling pathway);GO:0032088(negative regulation of NF-kappaB transcription factor activity);GO:0034162(toll-like receptor 9 signaling pathway);GO:0043433(negative regulation of sequence-specific DNA binding transcription factor activity);GO:0070555(response to interleukin-1)","04722(Neurotrophin signaling pathway);05152(Tuberculosis)","K04731","EC:2.7.11.1","interleukin 1 receptor associated kinase 2 [Source:HGNC Symbol;Acc:HGNC:6113]",{"v":2.107685,"d":"2.11"},{"v":1.518547,"d":"1.52"},{"v":1.38796165018271,"d":"1.39"},{"v":0.472967706348759,"d":"0.47"},{"v":0.450748269096829,"d":"0.45"},1,"up","no"]
["MSTRG.4527","ZNF410;AC005520.1;PTGR2","ENST00000555044;ENST00000556396;ENST00000324593;ENST00000556551;ENST00000555661;ENST00000556797;ENST00000555620;ENST00000442160;ENST00000554316;ENST00000557363;ENST00000412490;ENST00000557495;ENST00000556219;ENST00000556179;ENST00000639051;ENST00000267568;ENST00000398139;ENST00000334521;ENST00000541357;ENST00000553326;ENST00000540593;ENST00000556160;ENST00000615736;ENST00000557214;ENST00000555228;ENST00000554797","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0070062(extracellular exosome);GO:0006693(prostaglandin metabolic process);GO:0036132(13-prostaglandin reductase activity);GO:0047522(15-oxoprostaglandin 13-oxidase activity);GO:0005515(protein binding)","NA","NA","NA","zinc finger protein 410 [Source:HGNC Symbol;Acc:HGNC:20144];prostaglandin reductase 2 [Source:HGNC Symbol;Acc:HGNC:20149]",{"v":0.758412874079174,"d":"0.76"},{"v":1.09379759669535,"d":"1.09"},{"v":0.693375882677507,"d":"0.69"},{"v":-0.528290437963955,"d":"-0.53"},{"v":0.451554170015492,"d":"0.45"},1,"down","no"]
["MSTRG.13445","PSMG3","ENST00000288607;ENST00000404674;ENST00000252329","GO:0000502(proteasome complex);GO:0000502(proteasome complex)","NA","NA","NA","proteasome assembly chaperone 3 [Source:HGNC Symbol;Acc:HGNC:22420]",{"v":1.04641869846939,"d":"1.05"},{"v":1.53902903622449,"d":"1.54"},{"v":0.67992134900615,"d":"0.68"},{"v":-0.556560224938228,"d":"-0.56"},{"v":0.452075266374295,"d":"0.45"},1,"down","no"]
["MSTRG.139","PIK3CD","MSTRG.139.2;ENST00000628140;ENST00000361110;MSTRG.139.1;ENST00000377346;ENST00000484851;ENST00000479223;ENST00000536656;ENST00000543390;ENST00000481137","GO:0005622(intracellular);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0046854(phosphatidylinositol phosphorylation);GO:0048015(phosphatidylinositol-mediated signaling);GO:0005737(cytoplasm);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0005515(protein binding);GO:0007165(signal transduction);GO:0030154(cell differentiation);GO:0036092(phosphatidylinositol-3-phosphate biosynthetic process);GO:0002376(immune system process);GO:0045087(innate immune response);GO:0006935(chemotaxis);GO:0006954(inflammatory response);GO:0002250(adaptive immune response);GO:0005886(plasma membrane);GO:0042629(mast cell granule);GO:0006468(protein phosphorylation);GO:0001816(cytokine production);GO:0030593(neutrophil chemotaxis);GO:0005829(cytosol);GO:0042113(B cell activation);GO:0005942(phosphatidylinositol 3-kinase complex);GO:0016303(1-phosphatidylinositol-3-kinase activity);GO:0035004(phosphatidylinositol 3-kinase activity);GO:0035005(1-phosphatidylinositol-4-phosphate 3-kinase activity);GO:0046934(phosphatidylinositol-4,5-bisphosphate 3-kinase activity);GO:0001779(natural killer cell differentiation);GO:0002551(mast cell chemotaxis);GO:0002679(respiratory burst involved in defense response);GO:0006661(phosphatidylinositol biosynthetic process);GO:0007411(axon guidance);GO:0010628(positive regulation of gene expression);GO:0010818(T cell chemotaxis);GO:0014065(phosphatidylinositol 3-kinase signaling);GO:0014066(regulation of phosphatidylinositol 3-kinase signaling);GO:0030101(natural killer cell activation);GO:0030168(platelet activation);GO:0030217(T cell differentiation);GO:0030335(positive regulation of cell migration);GO:0033031(positive regulation of neutrophil apoptotic process);GO:0035747(natural killer cell chemotaxis);GO:0035754(B cell chemotaxis);GO:0038111(interleukin-7-mediated signaling pathway);GO:0042110(T cell activation);GO:0043303(mast cell degranulation);GO:0050852(T cell receptor signaling pathway);GO:0050853(B cell receptor signaling pathway);GO:0060374(mast cell differentiation);GO:0072672(neutrophil extravasation);GO:0072672(neutrophil extravasation)","00562(Inositol phosphate metabolism);04014(Ras signaling pathway);04015(Rap1 signaling pathway);04012(ErbB signaling pathway);04370(VEGF signaling pathway);04630(Jak-STAT signaling pathway);04668(TNF signaling pathway);04066(HIF-1 signaling pathway);04068(FoxO signaling pathway);04070(Phosphatidylinositol signaling system);04072(Phospholipase D signaling pathway);04071(Sphingolipid signaling pathway);04024(cAMP signaling pathway);04151(PI3K-Akt signaling pathway);04152(AMPK signaling pathway);04150(mTOR signaling pathway);04140(Autophagy - animal);04210(Apoptosis);04218(Cellular senescence);04510(Focal adhesion);04550(Signaling pathways regulating pluripotency of stem cells);04810(Regulation of actin cytoskeleton);04611(Platelet activation);04620(Toll-like receptor signaling pathway);04650(Natural killer cell mediated cytotoxicity);04660(T cell receptor signaling pathway);04662(B cell receptor signaling pathway);04664(Fc epsilon RI signaling pathway);04666(Fc gamma R-mediated phagocytosis);04670(Leukocyte transendothelial migration);04062(Chemokine signaling pathway);04910(Insulin signaling pathway);04923(Regulation of lipolysis in adipocyte);04915(Estrogen signaling pathway);04914(Progesterone-mediated oocyte maturation);04917(Prolactin signaling pathway);04926(Relaxin signaling pathway);04919(Thyroid hormone signaling pathway);04973(Carbohydrate digestion and absorption);04960(Aldosterone-regulated sodium reabsorption);04725(Cholinergic synapse);04722(Neurotrophin signaling pathway);04750(Inflammatory mediator regulation of TRP channels);04360(Axon guidance);04380(Osteoclast differentiation);04211(Longevity regulating pathway - mammal);04213(Longevity regulating pathway - multiple species);05200(Pathways in cancer);05230(Central carbon metabolism in cancer);05231(Choline metabolism in cancer);05205(Proteoglycans in cancer);05203(Viral carcinogenesis);05210(Colorectal cancer);05212(Pancreatic cancer);05225(Hepatocellular carcinoma);05226(Gastric cancer);05214(Glioma);05221(Acute myeloid leukemia);05220(Chronic myeloid leukemia);05218(Melanoma);05211(Renal cell carcinoma);05215(Prostate cancer);05213(Endometrial cancer);05224(Breast cancer);05222(Small cell lung cancer);05223(Non-small cell lung cancer);05418(Fluid shear stress and atherosclerosis);04930(Type II diabetes mellitus);04932(Non-alcoholic fatty liver disease (NAFLD));04931(Insulin resistance);04933(AGE-RAGE signaling pathway in diabetic complications);05100(Bacterial invasion of epithelial cells);05166(HTLV-I infection);05162(Measles);05164(Influenza A);05161(Hepatitis B);05160(Hepatitis C);05167(Kaposi's sarcoma-associated herpesvirus infection);05169(Epstein-Barr virus infection);05165(Human papillomavirus infection);05146(Amoebiasis);05142(Chagas disease (American trypanosomiasis));01521(EGFR tyrosine kinase inhibitor resistance);01524(Platinum drug resistance);01522(Endocrine resistance);01522(Endocrine resistance)","K00922","EC:2.7.1.153","phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta [Source:HGNC Symbol;Acc:HGNC:8977]",{"v":27.983508751325,"d":"27.98"},{"v":40.0349499990237,"d":"40.03"},{"v":0.69897698765722,"d":"0.70"},{"v":-0.516683136195548,"d":"-0.52"},{"v":0.454301592926371,"d":"0.45"},1,"down","no"]
["ENSG00000197563","PIGN","ENST00000638183;ENST00000640704;ENST00000640170;ENST00000587942;ENST00000588748;ENST00000589720;ENST00000639758;ENST00000638329;ENST00000586566;ENST00000639912;ENST00000638977;ENST00000640252;ENST00000585458;ENST00000400334;ENST00000638424;ENST00000638167;ENST00000589339;ENST00000640876;ENST00000640268;ENST00000589414;ENST00000639214;ENST00000638858;ENST00000639491;ENST00000585344;ENST00000357637","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0003824(catalytic activity);GO:0008152(metabolic process);GO:0005789(endoplasmic reticulum membrane);GO:0016740(transferase activity);GO:0006506(GPI anchor biosynthetic process);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0005783(endoplasmic reticulum);GO:0016254(preassembly of GPI anchor in ER membrane);GO:0016780(phosphotransferase activity, for other substituted phosphate groups);GO:0051377(mannose-ethanolamine phosphotransferase activity);GO:0008484(sulfuric ester hydrolase activity);GO:0008484(sulfuric ester hydrolase activity)","00563(Glycosylphosphatidylinositol(GPI)-anchor biosynthesis);00563(Glycosylphosphatidylinositol(GPI)-anchor biosynthesis)","K05285","EC:2.7.-.-","phosphatidylinositol glycan anchor biosynthesis class N [Source:HGNC Symbol;Acc:HGNC:8967]",{"v":0.230835980582013,"d":"0.23"},{"v":0.163525201547124,"d":"0.16"},{"v":1.41162327517751,"d":"1.41"},{"v":0.497355122922492,"d":"0.50"},{"v":0.455595471588331,"d":"0.46"},1,"up","no"]
["ENSG00000130758","MAP3K10","ENST00000253055;ENST00000601702;ENST00000594569;ENST00000594791;ENST00000597986;ENST00000594951","GO:0005737(cytoplasm);GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0042803(protein homodimerization activity);GO:0004709(MAP kinase kinase kinase activity);GO:0000186(activation of MAPKK activity);GO:0007224(smoothened signaling pathway);GO:0003714(transcription corepressor activity);GO:0007165(signal transduction);GO:0006915(apoptotic process);GO:0043433(negative regulation of sequence-specific DNA binding transcription factor activity);GO:0045892(negative regulation of transcription, DNA-templated);GO:0046777(protein autophosphorylation);GO:0018107(peptidyl-threonine phosphorylation);GO:0007257(activation of JUN kinase activity);GO:0046330(positive regulation of JNK cascade);GO:0043507(positive regulation of JUN kinase activity);GO:0043425(bHLH transcription factor binding);GO:0043065(positive regulation of apoptotic process);GO:0018105(peptidyl-serine phosphorylation);GO:0007254(JNK cascade);GO:0004706(JUN kinase kinase kinase activity);GO:0007256(activation of JNKK activity);GO:0008219(cell death);GO:0005622(intracellular);GO:0000165(MAPK cascade);GO:0004713(protein tyrosine kinase activity);GO:0018108(peptidyl-tyrosine phosphorylation);GO:0018108(peptidyl-tyrosine phosphorylation)","NA","NA","NA","mitogen-activated protein kinase kinase kinase 10 [Source:HGNC Symbol;Acc:HGNC:6849]",{"v":1.06672411782742,"d":"1.07"},{"v":0.763409216162944,"d":"0.76"},{"v":1.39731626923369,"d":"1.40"},{"v":0.482658597994198,"d":"0.48"},{"v":0.456521078006906,"d":"0.46"},1,"up","no"]
["ENSG00000151623","NR3C2","ENST00000503313;ENST00000503174;ENST00000358102;ENST00000344721;ENST00000625323;ENST00000342437","GO:0005634(nucleus);GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0005654(nucleoplasm);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0043565(sequence-specific DNA binding);GO:0043401(steroid hormone mediated signaling pathway);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0008289(lipid binding);GO:0005515(protein binding);GO:0005829(cytosol);GO:0005496(steroid binding);GO:0007165(signal transduction);GO:0006367(transcription initiation from RNA polymerase II promoter);GO:0043235(receptor complex);GO:0003707(steroid hormone receptor activity);GO:0003707(steroid hormone receptor activity)","04960(Aldosterone-regulated sodium reabsorption);04960(Aldosterone-regulated sodium reabsorption)","K08555","NA","nuclear receptor subfamily 3 group C member 2 [Source:HGNC Symbol;Acc:HGNC:7979]",{"v":0.680578490540336,"d":"0.68"},{"v":0.980150002421674,"d":"0.98"},{"v":0.694361565942783,"d":"0.69"},{"v":-0.526241000443545,"d":"-0.53"},{"v":0.458477012145417,"d":"0.46"},1,"down","no"]
["ENSG00000221926","TRIM16","ENST00000581224;ENST00000494759;ENST00000416464;ENST00000578744;ENST00000577886;ENST00000460728;ENST00000578237;ENST00000580388;ENST00000580110;ENST00000584142;ENST00000579630","GO:0005737(cytoplasm);GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0005829(cytosol);GO:0003677(DNA binding);GO:0005622(intracellular);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0045893(positive regulation of transcription, DNA-templated);GO:0019966(interleukin-1 binding);GO:0050718(positive regulation of interleukin-1 beta secretion);GO:0043967(histone H4 acetylation);GO:0016605(PML body);GO:0043966(histone H3 acetylation);GO:0045618(positive regulation of keratinocyte differentiation);GO:0032089(NACHT domain binding);GO:0032526(response to retinoic acid);GO:0046683(response to organophosphorus);GO:0048386(positive regulation of retinoic acid receptor signaling pathway);GO:0060416(response to growth hormone);GO:0003676(nucleic acid binding);GO:0006355(regulation of transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated)","NA","NA","NA","tripartite motif containing 16 [Source:HGNC Symbol;Acc:HGNC:17241]",{"v":0.403076885992908,"d":"0.40"},{"v":0.287972375886525,"d":"0.29"},{"v":1.39970677656853,"d":"1.40"},{"v":0.485124629814757,"d":"0.49"},{"v":0.459660792353344,"d":"0.46"},1,"up","no"]
["MSTRG.15264","TIMP1","ENST00000218388;ENST00000456754;ENST00000445623;ENST00000377017;ENST00000441738","GO:0046872(metal ion binding);GO:0008083(growth factor activity);GO:0010951(negative regulation of endopeptidase activity);GO:0008270(zinc ion binding);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0005581(collagen trimer);GO:0005125(cytokine activity);GO:0005615(extracellular space);GO:0030414(peptidase inhibitor activity);GO:0010466(negative regulation of peptidase activity);GO:0008191(metalloendopeptidase inhibitor activity);GO:0070062(extracellular exosome);GO:0044267(cellular protein metabolic process);GO:0043687(post-translational protein modification);GO:0005578(proteinaceous extracellular matrix);GO:0008284(positive regulation of cell proliferation);GO:0002576(platelet degranulation);GO:0005788(endoplasmic reticulum lumen);GO:0031093(platelet alpha granule lumen);GO:0034097(response to cytokine);GO:0022617(extracellular matrix disassembly);GO:2001044(regulation of integrin-mediated signaling pathway);GO:0004857(enzyme inhibitor activity);GO:0043086(negative regulation of catalytic activity);GO:0002020(protease binding);GO:0001775(cell activation);GO:0007568(aging);GO:0009725(response to hormone);GO:0010033(response to organic substance);GO:0042060(wound healing);GO:0043066(negative regulation of apoptotic process);GO:0043434(response to peptide hormone);GO:0051045(negative regulation of membrane protein ectodomain proteolysis);GO:0051216(cartilage development);GO:1901164(negative regulation of trophoblast cell migration);GO:1905049(negative regulation of metallopeptidase activity);GO:0005604(basement membrane);GO:0031012(extracellular matrix);GO:0031012(extracellular matrix)","04066(HIF-1 signaling pathway);04066(HIF-1 signaling pathway)","K16451","NA","TIMP metallopeptidase inhibitor 1 [Source:HGNC Symbol;Acc:HGNC:11820]",{"v":14.9107686015574,"d":"14.91"},{"v":21.2529946340039,"d":"21.25"},{"v":0.701584358267366,"d":"0.70"},{"v":-0.511311511445731,"d":"-0.51"},{"v":0.461256068900343,"d":"0.46"},1,"down","no"]
["MSTRG.10679","LSM3","ENST00000306024","GO:0003723(RNA binding);GO:0006397(mRNA processing);GO:0008380(RNA splicing);GO:0005634(nucleus);GO:0030529(intracellular ribonucleoprotein complex);GO:0005515(protein binding);GO:0005681(spliceosomal complex);GO:0000398(mRNA splicing, via spliceosome);GO:0000956(nuclear-transcribed mRNA catabolic process);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0033962(cytoplasmic mRNA processing body assembly);GO:0000932(P-body);GO:0046540(U4/U6 x U5 tri-snRNP complex);GO:0043928(exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay);GO:1990726(Lsm1-7-Pat1 complex);GO:0071013(catalytic step 2 spliceosome);GO:0071011(precatalytic spliceosome);GO:0005688(U6 snRNP)","03040(Spliceosome);03018(RNA degradation)","K12622","NA","LSM3 homolog, U6 small nuclear RNA and mRNA degradation associated [Source:HGNC Symbol;Acc:HGNC:17874]",{"v":2.004208,"d":"2.00"},{"v":2.857574,"d":"2.86"},{"v":0.701366963725174,"d":"0.70"},{"v":-0.511758617522087,"d":"-0.51"},{"v":0.461458739394126,"d":"0.46"},1,"down","no"]
["ENSG00000122417","ODF2L","ENST00000359242;ENST00000370566;ENST00000473792;ENST00000496592;ENST00000524695;ENST00000534092;ENST00000479890;ENST00000488879;ENST00000486557;ENST00000480440;ENST00000478286;ENST00000462648;ENST00000463933;ENST00000394733;ENST00000472368;ENST00000472144;ENST00000531412","GO:0005813(centrosome);GO:0005813(centrosome)","NA","NA","NA","outer dense fiber of sperm tails 2 like [Source:HGNC Symbol;Acc:HGNC:29225]",{"v":0.648546371444302,"d":"0.65"},{"v":0.471643598091393,"d":"0.47"},{"v":1.3750772279509,"d":"1.38"},{"v":0.459512646457666,"d":"0.46"},{"v":0.463358898995273,"d":"0.46"},1,"up","no"]
["MSTRG.10796","CLASP2","ENST00000399362;ENST00000464961;ENST00000480013;ENST00000635664;ENST00000461133;ENST00000491045;ENST00000359576;ENST00000496954;ENST00000467956;ENST00000480385;ENST00000494261;ENST00000468888;ENST00000482896;ENST00000333778;ENST00000462878;ENST00000476251;ENST00000486796","GO:0005794(Golgi apparatus);GO:0005829(cytosol);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0051301(cell division);GO:0005694(chromosome);GO:0005886(plasma membrane);GO:0005856(cytoskeleton);GO:0042995(cell projection);GO:0005515(protein binding);GO:0007049(cell cycle);GO:0005874(microtubule);GO:0005925(focal adhesion);GO:0008017(microtubule binding);GO:0005815(microtubule organizing center);GO:0005819(spindle);GO:0000775(chromosome, centromeric region);GO:0000776(kinetochore);GO:0000777(condensed chromosome kinetochore);GO:0031252(cell leading edge);GO:0005802(trans-Golgi network);GO:0032587(ruffle membrane);GO:0010717(regulation of epithelial to mesenchymal transition);GO:0007052(mitotic spindle organization);GO:0007062(sister chromatid cohesion);GO:0045921(positive regulation of exocytosis);GO:0000226(microtubule cytoskeleton organization);GO:0002162(dystroglycan binding);GO:0010458(exit from mitosis);GO:0051895(negative regulation of focal adhesion assembly);GO:0090002(establishment of protein localization to plasma membrane);GO:0007030(Golgi organization);GO:0005881(cytoplasmic microtubule);GO:0010634(positive regulation of epithelial cell migration);GO:0005828(kinetochore microtubule);GO:0032886(regulation of microtubule-based process);GO:0005938(cell cortex);GO:0072686(mitotic spindle);GO:0051010(microtubule plus-end binding);GO:0006903(vesicle targeting);GO:0007020(microtubule nucleation);GO:0007026(negative regulation of microtubule depolymerization);GO:0007163(establishment or maintenance of cell polarity);GO:0010470(regulation of gastrulation);GO:0031023(microtubule organizing center organization);GO:0031110(regulation of microtubule polymerization or depolymerization);GO:0034453(microtubule anchoring);GO:0051497(negative regulation of stress fiber assembly);GO:0090091(positive regulation of extracellular matrix disassembly);GO:1903690(negative regulation of wound healing, spreading of epidermal cells);GO:1904261(positive regulation of basement membrane assembly involved in embryonic body morphogenesis);GO:0045180(basal cortex);GO:0045180(basal cortex)","NA","NA","NA","cytoplasmic linker associated protein 2 [Source:HGNC Symbol;Acc:HGNC:17078]",{"v":0.790646070804023,"d":"0.79"},{"v":1.12507013759779,"d":"1.13"},{"v":0.702752694593941,"d":"0.70"},{"v":-0.508911014485425,"d":"-0.51"},{"v":0.465120308509379,"d":"0.47"},1,"down","no"]
["MSTRG.15506","ATP6AP1","ENST00000619046;ENST00000369762;ENST00000449556;ENST00000422890;ENST00000455205;ENST00000429585;ENST00000491569;ENST00000484908;ENST00000439372","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0006811(ion transport);GO:0006879(cellular iron ion homeostasis);GO:0015991(ATP hydrolysis coupled proton transport);GO:0015992(proton transport);GO:0046961(proton-transporting ATPase activity, rotational mechanism);GO:0033180(proton-transporting V-type ATPase, V1 domain);GO:0046933(proton-transporting ATP synthase activity, rotational mechanism);GO:0070062(extracellular exosome);GO:0034220(ion transmembrane transport);GO:0010008(endosome membrane);GO:0070374(positive regulation of ERK1 and ERK2 cascade);GO:0005215(transporter activity);GO:0045921(positive regulation of exocytosis);GO:0045780(positive regulation of bone resorption);GO:0033116(endoplasmic reticulum-Golgi intermediate compartment membrane);GO:0008286(insulin receptor signaling pathway);GO:0033572(transferrin transport);GO:0017137(Rab GTPase binding);GO:0036295(cellular response to increased oxygen levels);GO:0045669(positive regulation of osteoblast differentiation);GO:0045851(pH reduction);GO:0016469(proton-transporting two-sector ATPase complex);GO:0051656(establishment of organelle localization);GO:2001206(positive regulation of osteoclast development);GO:2001206(positive regulation of osteoclast development)","00190(Oxidative phosphorylation);04145(Phagosome);04142(Lysosome);05323(Rheumatoid arthritis);05110(Vibrio cholerae infection);05120(Epithelial cell signaling in Helicobacter pylori infection);05152(Tuberculosis);05161(Hepatitis B);05161(Hepatitis B)","K03662","NA","ATPase H+ transporting accessory protein 1 [Source:HGNC Symbol;Acc:HGNC:868]",{"v":13.6513786807944,"d":"13.65"},{"v":19.3667758292383,"d":"19.37"},{"v":0.704886492267067,"d":"0.70"},{"v":-0.50453713557108,"d":"-0.50"},{"v":0.46603554459835,"d":"0.47"},1,"down","no"]
["MSTRG.1616","APBB1IP","ENST00000376236;ENST00000493857;ENST00000356785","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005829(cytosol);GO:0007165(signal transduction);GO:0005886(plasma membrane);GO:0005856(cytoskeleton);GO:0042995(cell projection);GO:0005515(protein binding);GO:0030054(cell junction);GO:0005925(focal adhesion);GO:0030027(lamellipodium);GO:0002291(T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell);GO:0045785(positive regulation of cell adhesion);GO:0042101(T cell receptor complex);GO:0042101(T cell receptor complex)","04015(Rap1 signaling pathway);04611(Platelet activation);04611(Platelet activation)","K17704","NA","amyloid beta precursor protein binding family B member 1 interacting protein [Source:HGNC Symbol;Acc:HGNC:17379]",{"v":28.0074648281839,"d":"28.01"},{"v":39.6831973401156,"d":"39.68"},{"v":0.705776416858207,"d":"0.71"},{"v":-0.502716870848136,"d":"-0.50"},{"v":0.467337457378449,"d":"0.47"},1,"down","no"]
["MSTRG.8890","RMND5A","ENST00000283632;ENST00000472843","GO:0005515(protein binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0004842(ubiquitin-protein transferase activity);GO:0043161(proteasome-mediated ubiquitin-dependent protein catabolic process);GO:0042787(protein ubiquitination involved in ubiquitin-dependent protein catabolic process);GO:0034657(GID complex);GO:0034657(GID complex)","NA","NA","NA","required for meiotic nuclear division 5 homolog A [Source:HGNC Symbol;Acc:HGNC:25850]",{"v":7.64646816211052,"d":"7.65"},{"v":10.8332170967078,"d":"10.83"},{"v":0.705835403634094,"d":"0.71"},{"v":-0.502596299558118,"d":"-0.50"},{"v":0.46753025480892,"d":"0.47"},1,"down","no"]
["MSTRG.1985","VTI1A","ENST00000393077;ENST00000483122;ENST00000432306;ENST00000489142;ENST00000480057;ENST00000496445;ENST00000489357;ENST00000494728;ENST00000472892","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0006886(intracellular protein transport);GO:0015031(protein transport);GO:0016192(vesicle-mediated transport);GO:0005794(Golgi apparatus);GO:0005829(cytosol);GO:0043231(intracellular membrane-bounded organelle);GO:0000139(Golgi membrane);GO:0031410(cytoplasmic vesicle);GO:0031902(late endosome membrane);GO:0006891(intra-Golgi vesicle-mediated transport);GO:0005484(SNAP receptor activity);GO:0042147(retrograde transport, endosome to Golgi);GO:0005776(autophagosome);GO:0000149(SNARE binding);GO:0006623(protein targeting to vacuole);GO:0006888(ER to Golgi vesicle-mediated transport);GO:0006896(Golgi to vacuole transport);GO:0048280(vesicle fusion with Golgi apparatus);GO:0005789(endoplasmic reticulum membrane);GO:0012507(ER to Golgi transport vesicle membrane);GO:0032588(trans-Golgi network membrane);GO:0005515(protein binding);GO:0048471(perinuclear region of cytoplasm);GO:0090161(Golgi ribbon formation);GO:0031201(SNARE complex);GO:0030136(clathrin-coated vesicle);GO:0043025(neuronal cell body);GO:0005768(endosome);GO:0008021(synaptic vesicle);GO:0044306(neuron projection terminus);GO:0006914(autophagy);GO:0050882(voluntary musculoskeletal movement);GO:0050882(voluntary musculoskeletal movement)","04130(SNARE interactions in vesicular transport);04130(SNARE interactions in vesicular transport)","K08493","NA","vesicle transport through interaction with t-SNAREs 1A [Source:HGNC Symbol;Acc:HGNC:17792]",{"v":1.5515219103235,"d":"1.55"},{"v":2.20354027545195,"d":"2.20"},{"v":0.704104176178618,"d":"0.70"},{"v":-0.506139195375263,"d":"-0.51"},{"v":0.468970624503905,"d":"0.47"},1,"down","no"]
["MSTRG.12575","RGS14","ENST00000425155;ENST00000408923;ENST00000514713;ENST00000509289;MSTRG.12575.2;ENST00000502731;ENST00000503044;ENST00000512000;ENST00000514102;ENST00000506944;ENST00000504631;ENST00000503110;ENST00000512490;ENST00000511890","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0035556(intracellular signal transduction);GO:0007165(signal transduction);GO:0051301(cell division);GO:0005886(plasma membrane);GO:0030695(GTPase regulator activity);GO:0043547(positive regulation of GTPase activity);GO:0005856(cytoskeleton);GO:0042995(cell projection);GO:0005515(protein binding);GO:0005057(signal transducer activity, downstream of receptor);GO:0005096(GTPase activator activity);GO:0007049(cell cycle);GO:0008017(microtubule binding);GO:0030054(cell junction);GO:0045202(synapse);GO:0045211(postsynaptic membrane);GO:0005874(microtubule);GO:0005092(GDP-dissociation inhibitor activity);GO:0030425(dendrite);GO:0000922(spindle pole);GO:0005813(centrosome);GO:0005815(microtubule organizing center);GO:0005819(spindle);GO:0007051(spindle organization);GO:0007059(chromosome segregation);GO:0014069(postsynaptic density);GO:0043197(dendritic spine);GO:0001965(G-protein alpha-subunit binding);GO:0007616(long-term memory);GO:0006979(response to oxidative stress);GO:0016605(PML body);GO:0048008(platelet-derived growth factor receptor signaling pathway);GO:0007612(learning);GO:0009968(negative regulation of signal transduction);GO:0070373(negative regulation of ERK1 and ERK2 cascade);GO:0008277(regulation of G-protein coupled receptor protein signaling pathway);GO:0019901(protein kinase binding);GO:0030159(receptor signaling complex scaffold activity);GO:0032794(GTPase activating protein binding);GO:0000278(mitotic cell cycle);GO:0006913(nucleocytoplasmic transport);GO:0008542(visual learning);GO:0010070(zygote asymmetric cell division);GO:0031914(negative regulation of synaptic plasticity);GO:0043407(negative regulation of MAP kinase activity);GO:0043620(regulation of DNA-templated transcription in response to stress);GO:0050769(positive regulation of neurogenesis);GO:0060291(long-term synaptic potentiation);GO:0016604(nuclear body);GO:0005622(intracellular);GO:0050790(regulation of catalytic activity);GO:0050790(regulation of catalytic activity)","04015(Rap1 signaling pathway);04015(Rap1 signaling pathway)","K17706","NA","regulator of G protein signaling 14 [Source:HGNC Symbol;Acc:HGNC:9996]",{"v":18.9763911222017,"d":"18.98"},{"v":26.8606525330524,"d":"26.86"},{"v":0.706475432748739,"d":"0.71"},{"v":-0.50128870229391,"d":"-0.50"},{"v":0.469499277682786,"d":"0.47"},1,"down","no"]
["MSTRG.7855","HOOK2;RTBDN","ENST00000264827;ENST00000397668;ENST00000589272;ENST00000589915;ENST00000590839;ENST00000588052;ENST00000586719;ENST00000592512;ENST00000592259;ENST00000591251;ENST00000586284;ENST00000589134;ENST00000589398;ENST00000591839;ENST00000592808","GO:0006810(transport);GO:0005737(cytoplasm);GO:0015031(protein transport);GO:0043231(intracellular membrane-bounded organelle);GO:0005829(cytosol);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0005874(microtubule);GO:0005813(centrosome);GO:0005815(microtubule organizing center);GO:0008333(endosome to lysosome transport);GO:0008017(microtubule binding);GO:0051959(dynein light intermediate chain binding);GO:0030705(cytoskeleton-dependent intracellular transport);GO:0031122(cytoplasmic microtubule organization);GO:0042802(identical protein binding);GO:0007040(lysosome organization);GO:0007032(endosome organization);GO:0006897(endocytosis);GO:0045022(early endosome to late endosome transport);GO:0030897(HOPS complex);GO:0070695(FHF complex);GO:0016020(membrane);GO:0005886(plasma membrane);GO:0005576(extracellular region);GO:0005578(proteinaceous extracellular matrix);GO:0033165(interphotoreceptor matrix);GO:1902444(riboflavin binding);GO:0019897(extrinsic component of plasma membrane);GO:0070695(FHF complex)","NA","NA","NA","hook microtubule tethering protein 2 [Source:HGNC Symbol;Acc:HGNC:19885];retbindin [Source:HGNC Symbol;Acc:HGNC:30310]",{"v":0.519724376522445,"d":"0.52"},{"v":0.378167293701427,"d":"0.38"},{"v":1.37432397031347,"d":"1.37"},{"v":0.458722131718739,"d":"0.46"},{"v":0.470970470481304,"d":"0.47"},1,"up","no"]
["MSTRG.5983","SETD6","ENST00000394266;ENST00000468223;ENST00000492050;ENST00000467320;ENST00000422445;ENST00000491587;ENST00000310682;ENST00000427443;ENST00000463954;ENST00000219315","GO:0005634(nucleus);GO:0005829(cytosol);GO:0008168(methyltransferase activity);GO:0016740(transferase activity);GO:0032259(methylation);GO:0005515(protein binding);GO:0018026(peptidyl-lysine monomethylation);GO:0016279(protein-lysine N-methyltransferase activity);GO:0005654(nucleoplasm);GO:0048863(stem cell differentiation);GO:0032088(negative regulation of NF-kappaB transcription factor activity);GO:0051059(NF-kappaB binding);GO:0019827(stem cell population maintenance);GO:0050727(regulation of inflammatory response);GO:0034968(histone lysine methylation);GO:0034968(histone lysine methylation)","NA","NA","NA","SET domain containing 6 [Source:HGNC Symbol;Acc:HGNC:26116]",{"v":1.91661154588421,"d":"1.92"},{"v":1.40207452028358,"d":"1.40"},{"v":1.36698265188969,"d":"1.37"},{"v":0.45099493409867,"d":"0.45"},{"v":0.472490911557418,"d":"0.47"},1,"up","no"]
["ENSG00000101928","MOSPD1","ENST00000370777;ENST00000370783;ENST00000370779;ENST00000491609;ENST00000489890;ENST00000462060","GO:0048471(perinuclear region of cytoplasm);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0005737(cytoplasm);GO:0005634(nucleus);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0000122(negative regulation of transcription from RNA polymerase II promoter)","NA","NA","NA","motile sperm domain containing 1 [Source:HGNC Symbol;Acc:HGNC:25235]",{"v":0.637862603364486,"d":"0.64"},{"v":0.450240018691589,"d":"0.45"},{"v":1.41671681077603,"d":"1.42"},{"v":0.502551405031031,"d":"0.50"},{"v":0.472634580642742,"d":"0.47"},1,"up","no"]
["ENSG00000173218","VANGL1","ENST00000355485;ENST00000369509","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0007275(multicellular organism development);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0060071(Wnt signaling pathway, planar cell polarity pathway);GO:0043473(pigmentation);GO:0016328(lateral plasma membrane);GO:0016328(lateral plasma membrane)","04310(Wnt signaling pathway);04310(Wnt signaling pathway)","K04510","NA","VANGL planar cell polarity protein 1 [Source:HGNC Symbol;Acc:HGNC:15512]",{"v":0.368848648642684,"d":"0.37"},{"v":0.268228888655926,"d":"0.27"},{"v":1.37512648429092,"d":"1.38"},{"v":0.459564323994983,"d":"0.46"},{"v":0.473419442949168,"d":"0.47"},1,"up","no"]
["MSTRG.3383","NR4A1","ENST00000550557;ENST00000548733;ENST00000549102;ENST00000565848;ENST00000546842;ENST00000548232;ENST00000478250;ENST00000243050;ENST00000550339;ENST00000545748","GO:0005634(nucleus);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0004879(RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding);GO:0030522(intracellular receptor signaling pathway);GO:0008270(zinc ion binding);GO:0005829(cytosol);GO:0006351(transcription, DNA-templated);GO:0031965(nuclear membrane);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0043565(sequence-specific DNA binding);GO:0046872(metal ion binding);GO:0006366(transcription from RNA polymerase II promoter);GO:0003707(steroid hormone receptor activity);GO:0043401(steroid hormone mediated signaling pathway);GO:0001077(transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0008134(transcription factor binding);GO:0035259(glucocorticoid receptor binding);GO:0042803(protein homodimerization activity);GO:0046982(protein heterodimerization activity);GO:0006915(apoptotic process);GO:0035914(skeletal muscle cell differentiation);GO:0043065(positive regulation of apoptotic process);GO:0043154(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process);GO:0045444(fat cell differentiation);GO:0045786(negative regulation of cell cycle);GO:0045893(positive regulation of transcription, DNA-templated);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0061469(regulation of type B pancreatic cell proliferation);GO:0071310(cellular response to organic substance);GO:0071376(cellular response to corticotropin-releasing hormone stimulus);GO:0005667(transcription factor complex);GO:0005737(cytoplasm);GO:0005515(protein binding);GO:0005654(nucleoplasm);GO:0001938(positive regulation of endothelial cell proliferation);GO:0007165(signal transduction);GO:0006367(transcription initiation from RNA polymerase II promoter);GO:0002042(cell migration involved in sprouting angiogenesis);GO:0035767(endothelial cell chemotaxis);GO:0035924(cellular response to vascular endothelial growth factor stimulus);GO:0044344(cellular response to fibroblast growth factor stimulus);GO:0044344(cellular response to fibroblast growth factor stimulus)","04010(MAPK signaling pathway);04151(PI3K-Akt signaling pathway);04925(Aldosterone synthesis and secretion);04927(Cortisol synthesis and secretion);04927(Cortisol synthesis and secretion)","K04465","NA","nuclear receptor subfamily 4 group A member 1 [Source:HGNC Symbol;Acc:HGNC:7980]",{"v":0.322538595339273,"d":"0.32"},{"v":0.461188945853324,"d":"0.46"},{"v":0.699363239815927,"d":"0.70"},{"v":-0.51588612831846,"d":"-0.52"},{"v":0.474529744677469,"d":"0.47"},1,"down","no"]
["MSTRG.7","B3GALT6","ENST00000379198","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016740(transferase activity);GO:0016757(transferase activity, transferring glycosyl groups);GO:0006486(protein glycosylation);GO:0005794(Golgi apparatus);GO:0008378(galactosyltransferase activity);GO:0032580(Golgi cisterna membrane);GO:0000139(Golgi membrane);GO:0030203(glycosaminoglycan metabolic process);GO:0015012(heparan sulfate proteoglycan biosynthetic process);GO:0006024(glycosaminoglycan biosynthetic process);GO:0005797(Golgi medial cisterna);GO:0035250(UDP-galactosyltransferase activity);GO:0030206(chondroitin sulfate biosynthetic process);GO:0008499(UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity);GO:0047220(galactosylxylosylprotein 3-beta-galactosyltransferase activity)","00532(Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate);00534(Glycosaminoglycan biosynthesis - heparan sulfate / heparin)","K00734","EC:2.4.1.134","beta-1,3-galactosyltransferase 6 [Source:HGNC Symbol;Acc:HGNC:17978]",{"v":2.055279,"d":"2.06"},{"v":1.503709,"d":"1.50"},{"v":1.3668063435146,"d":"1.37"},{"v":0.450808848618641,"d":"0.45"},{"v":0.47621748671409,"d":"0.48"},1,"up","no"]
["MSTRG.4454","JKAMP","ENST00000261247;ENST00000554754;ENST00000556985;ENST00000602482;ENST00000553647;ENST00000553156;ENST00000425728;ENST00000553941;ENST00000554721;ENST00000554271;ENST00000616435","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0006986(response to unfolded protein);GO:0031625(ubiquitin protein ligase binding);GO:0030433(ubiquitin-dependent ERAD pathway);GO:0030433(ubiquitin-dependent ERAD pathway)","NA","NA","NA","JNK1/MAPK8-associated membrane protein [Source:HGNC Symbol;Acc:HGNC:20184]",{"v":1.67104577908046,"d":"1.67"},{"v":2.36827829885057,"d":"2.37"},{"v":0.70559519119501,"d":"0.71"},{"v":-0.503087366280411,"d":"-0.50"},{"v":0.47668313208705,"d":"0.48"},1,"down","no"]
["MSTRG.3007","WNK1","MSTRG.3007.1;MSTRG.3007.3;MSTRG.3007.2;ENST00000537687;MSTRG.3007.4;ENST00000535572;ENST00000542543;ENST00000540360;ENST00000340908;ENST00000544965;ENST00000540885;ENST00000537603;ENST00000315939;ENST00000545285;ENST00000535698;ENST00000447667;ENST00000545055;ENST00000542424;ENST00000534872;ENST00000543065;ENST00000544559;ENST00000530271;ENST00000574564","GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0005829(cytosol);GO:0005737(cytoplasm);GO:0000166(nucleotide binding);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0006811(ion transport);GO:0005515(protein binding);GO:0004860(protein kinase inhibitor activity);GO:0071901(negative regulation of protein serine/threonine kinase activity);GO:0032147(activation of protein kinase activity);GO:0048666(neuron development);GO:0019902(phosphatase binding);GO:0010923(negative regulation of phosphatase activity);GO:0006469(negative regulation of protein kinase activity);GO:0035556(intracellular signal transduction);GO:0016020(membrane);GO:0019869(chloride channel inhibitor activity);GO:0002028(regulation of sodium ion transport);GO:0019901(protein kinase binding);GO:0018107(peptidyl-threonine phosphorylation);GO:0030295(protein kinase activator activity);GO:0023016(signal transduction by trans-phosphorylation);GO:0050794(regulation of cellular process);GO:0000287(magnesium ion binding);GO:0019870(potassium channel inhibitor activity);GO:0030291(protein serine/threonine kinase inhibitor activity);GO:0003084(positive regulation of systemic arterial blood pressure);GO:0033673(negative regulation of kinase activity);GO:0046777(protein autophosphorylation);GO:0071277(cellular response to calcium ion);GO:0090188(negative regulation of pancreatic juice secretion);GO:0090188(negative regulation of pancreatic juice secretion)","NA","NA","NA","WNK lysine deficient protein kinase 1 [Source:HGNC Symbol;Acc:HGNC:14540]",{"v":18.3687964266649,"d":"18.37"},{"v":13.5602352629121,"d":"13.56"},{"v":1.35460750278459,"d":"1.35"},{"v":0.437874891568619,"d":"0.44"},{"v":0.478452389040871,"d":"0.48"},1,"up","no"]
["MSTRG.3931","UBL3","ENST00000380680","GO:0016020(membrane);GO:0005886(plasma membrane);GO:0070062(extracellular exosome);GO:0005622(intracellular)","NA","NA","NA","ubiquitin like 3 [Source:HGNC Symbol;Acc:HGNC:12504]",{"v":9.648042,"d":"9.65"},{"v":13.557469,"d":"13.56"},{"v":0.71164035115994,"d":"0.71"},{"v":-0.490779778818711,"d":"-0.49"},{"v":0.479193933288553,"d":"0.48"},1,"down","no"]
["ENSG00000108576","SLC6A4","ENST00000261707;ENST00000401766","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0046872(metal ion binding);GO:0005887(integral component of plasma membrane);GO:0005829(cytosol);GO:0015293(symporter activity);GO:0055085(transmembrane transport);GO:0005886(plasma membrane);GO:0005328(neurotransmitter:sodium symporter activity);GO:0006836(neurotransmitter transport);GO:0098793(presynapse);GO:0045121(membrane raft);GO:0072488(ammonium transmembrane transport);GO:0005515(protein binding);GO:0005768(endosome);GO:0051015(actin filament binding);GO:0012505(endomembrane system);GO:0010008(endosome membrane);GO:0043005(neuron projection);GO:0005335(serotonin:sodium symporter activity);GO:0051259(protein oligomerization);GO:0009636(response to toxic substance);GO:0042136(neurotransmitter biosynthetic process);GO:0017137(Rab GTPase binding);GO:0035176(social behavior);GO:0008504(monoamine transmembrane transporter activity);GO:0015844(monoamine transport);GO:0005330(dopamine:sodium symporter activity);GO:0015222(serotonin transmembrane transporter activity);GO:0006837(serotonin transport);GO:0021794(thalamus development);GO:0046621(negative regulation of organ growth);GO:0048854(brain morphogenesis);GO:0051583(dopamine uptake involved in synaptic transmission);GO:0051610(serotonin uptake);GO:0017022(myosin binding);GO:0017075(syntaxin-1 binding);GO:0019811(cocaine binding);GO:0042803(protein homodimerization activity);GO:0050998(nitric-oxide synthase binding);GO:0001666(response to hypoxia);GO:0007420(brain development);GO:0007584(response to nutrient);GO:0007613(memory);GO:0007623(circadian rhythm);GO:0010033(response to organic substance);GO:0010628(positive regulation of gene expression);GO:0014064(positive regulation of serotonin secretion);GO:0021941(negative regulation of cerebellar granule cell precursor proliferation);GO:0032227(negative regulation of synaptic transmission, dopaminergic);GO:0032355(response to estradiol);GO:0042310(vasoconstriction);GO:0042493(response to drug);GO:0042713(sperm ejaculation);GO:0045665(negative regulation of neuron differentiation);GO:0045787(positive regulation of cell cycle);GO:0051260(protein homooligomerization);GO:0071300(cellular response to retinoic acid);GO:0071310(cellular response to organic substance);GO:0071321(cellular response to cGMP);GO:0071321(cellular response to cGMP)","04726(Serotonergic synapse);04726(Serotonergic synapse)","K05037","NA","solute carrier family 6 member 4 [Source:HGNC Symbol;Acc:HGNC:11050]",{"v":0.22617967062867,"d":"0.23"},{"v":0.322116885579264,"d":"0.32"},{"v":0.70216645185157,"d":"0.70"},{"v":-0.510115026187315,"d":"-0.51"},{"v":0.47945247838507,"d":"0.48"},1,"down","no"]
["ENSG00000167515","TRAPPC2L","ENST00000301021;ENST00000565205;ENST00000565309;ENST00000565504;ENST00000564547;ENST00000564365;ENST00000568583;ENST00000563514;ENST00000562125;ENST00000567895;ENST00000567312;ENST00000564404;ENST00000562792;ENST00000625770","GO:0006810(transport);GO:0005622(intracellular);GO:0006888(ER to Golgi vesicle-mediated transport);GO:0005737(cytoplasm);GO:0043231(intracellular membrane-bounded organelle);GO:0005829(cytosol);GO:0005794(Golgi apparatus);GO:0005783(endoplasmic reticulum);GO:0043547(positive regulation of GTPase activity);GO:0005515(protein binding);GO:0048471(perinuclear region of cytoplasm);GO:0016192(vesicle-mediated transport);GO:0000139(Golgi membrane);GO:0017112(Rab guanyl-nucleotide exchange factor activity);GO:0061024(membrane organization);GO:0051259(protein oligomerization);GO:0048208(COPII vesicle coating);GO:0030008(TRAPP complex);GO:0030008(TRAPP complex)","NA","NA","NA","trafficking protein particle complex 2 like [Source:HGNC Symbol;Acc:HGNC:30887]",{"v":1.90063458928972,"d":"1.90"},{"v":1.40107345507506,"d":"1.40"},{"v":1.35655599098328,"d":"1.36"},{"v":0.439948595166307,"d":"0.44"},{"v":0.480529073522823,"d":"0.48"},1,"up","no"]
["MSTRG.7636","GADD45B","ENST00000215631;ENST00000592937;ENST00000585359;ENST00000587345;ENST00000593043;ENST00000586759;ENST00000587887","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005515(protein binding);GO:0006915(apoptotic process);GO:0007275(multicellular organism development);GO:0030154(cell differentiation);GO:0051726(regulation of cell cycle);GO:0006950(response to stress);GO:0043065(positive regulation of apoptotic process);GO:0046330(positive regulation of JNK cascade);GO:0000185(activation of MAPKKK activity);GO:0000186(activation of MAPKK activity);GO:0006469(negative regulation of protein kinase activity);GO:1900745(positive regulation of p38MAPK cascade);GO:1900745(positive regulation of p38MAPK cascade)","04010(MAPK signaling pathway);04064(NF-kappa B signaling pathway);04068(FoxO signaling pathway);04110(Cell cycle);04210(Apoptosis);04115(p53 signaling pathway);04218(Cellular senescence);05200(Pathways in cancer);05202(Transcriptional misregulation in cancers);05210(Colorectal cancer);05212(Pancreatic cancer);05225(Hepatocellular carcinoma);05226(Gastric cancer);05214(Glioma);05216(Thyroid cancer);05220(Chronic myeloid leukemia);05217(Basal cell carcinoma);05218(Melanoma);05213(Endometrial cancer);05224(Breast cancer);05222(Small cell lung cancer);05223(Non-small cell lung cancer);05223(Non-small cell lung cancer)","K04402","NA","growth arrest and DNA damage inducible beta [Source:HGNC Symbol;Acc:HGNC:4096]",{"v":9.02546135032741,"d":"9.03"},{"v":12.6793353723106,"d":"12.68"},{"v":0.71182448332721,"d":"0.71"},{"v":-0.490406539438806,"d":"-0.49"},{"v":0.48122418619502,"d":"0.48"},1,"down","no"]
["ENSG00000115556","PLCD4","ENST00000473443;ENST00000450993;ENST00000459791","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0046872(metal ion binding);GO:0005829(cytosol);GO:0016787(hydrolase activity);GO:0035556(intracellular signal transduction);GO:0005509(calcium ion binding);GO:0031965(nuclear membrane);GO:0007165(signal transduction);GO:0005622(intracellular);GO:0006629(lipid metabolic process);GO:0016042(lipid catabolic process);GO:0005886(plasma membrane);GO:0005783(endoplasmic reticulum);GO:0004871(signal transducer activity);GO:0008081(phosphoric diester hydrolase activity);GO:0046488(phosphatidylinositol metabolic process);GO:0004435(phosphatidylinositol phospholipase C activity);GO:0004629(phospholipase C activity);GO:0005789(endoplasmic reticulum membrane);GO:0007340(acrosome reaction);GO:0043647(inositol phosphate metabolic process);GO:0043647(inositol phosphate metabolic process)","00562(Inositol phosphate metabolism);04020(Calcium signaling pathway);04070(Phosphatidylinositol signaling system);04919(Thyroid hormone signaling pathway);04933(AGE-RAGE signaling pathway in diabetic complications);04933(AGE-RAGE signaling pathway in diabetic complications)","K05857","EC:3.1.4.11","phospholipase C delta 4 [Source:HGNC Symbol;Acc:HGNC:9062]",{"v":0.321051056758139,"d":"0.32"},{"v":0.231109065280382,"d":"0.23"},{"v":1.38917552355049,"d":"1.39"},{"v":0.474228896624887,"d":"0.47"},{"v":0.483065643313121,"d":"0.48"},1,"up","no"]
["MSTRG.12453","CSF1R","ENST00000286301;ENST00000504875;ENST00000511344;ENST00000502660;ENST00000509861;ENST00000515068;ENST00000513609","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0004672(protein kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0007169(transmembrane receptor protein tyrosine kinase signaling pathway);GO:0018108(peptidyl-tyrosine phosphorylation);GO:0004714(transmembrane receptor protein tyrosine kinase activity);GO:0019955(cytokine binding);GO:0019221(cytokine-mediated signaling pathway);GO:0043231(intracellular membrane-bounded organelle);GO:0000166(nucleotide binding);GO:0005654(nucleoplasm);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0004713(protein tyrosine kinase activity);GO:0005886(plasma membrane);GO:0048015(phosphatidylinositol-mediated signaling);GO:0002376(immune system process);GO:0045087(innate immune response);GO:0006954(inflammatory response);GO:0046488(phosphatidylinositol metabolic process);GO:0001934(positive regulation of protein phosphorylation);GO:0071902(positive regulation of protein serine/threonine kinase activity);GO:0008283(cell proliferation);GO:0030335(positive regulation of cell migration);GO:0005887(integral component of plasma membrane);GO:0008360(regulation of cell shape);GO:0008284(positive regulation of cell proliferation);GO:0042803(protein homodimerization activity);GO:0007165(signal transduction);GO:0070374(positive regulation of ERK1 and ERK2 cascade);GO:0007275(multicellular organism development);GO:0009986(cell surface);GO:0036006(cellular response to macrophage colony-stimulating factor stimulus);GO:0046777(protein autophosphorylation);GO:0030097(hemopoiesis);GO:0030316(osteoclast differentiation);GO:2000249(regulation of actin cytoskeleton reorganization);GO:0090197(positive regulation of chemokine secretion);GO:0042531(positive regulation of tyrosine phosphorylation of STAT protein);GO:0071345(cellular response to cytokine stimulus);GO:2000147(positive regulation of cell motility);GO:0061098(positive regulation of protein tyrosine kinase activity);GO:0045124(regulation of bone resorption);GO:0005011(macrophage colony-stimulating factor receptor activity);GO:0019903(protein phosphatase binding);GO:0007411(axon guidance);GO:0008285(negative regulation of cell proliferation);GO:0021772(olfactory bulb development);GO:0021879(forebrain neuron differentiation);GO:0030224(monocyte differentiation);GO:0030225(macrophage differentiation);GO:0031529(ruffle organization);GO:0038145(macrophage colony-stimulating factor signaling pathway);GO:0043066(negative regulation of apoptotic process);GO:0045217(cell-cell junction maintenance);GO:0060603(mammary gland duct morphogenesis);GO:1990682(CSF1-CSF1R complex);GO:1990682(CSF1-CSF1R complex)","04014(Ras signaling pathway);04015(Rap1 signaling pathway);04010(MAPK signaling pathway);04151(PI3K-Akt signaling pathway);04060(Cytokine-cytokine receptor interaction);04640(Hematopoietic cell lineage);04380(Osteoclast differentiation);05200(Pathways in cancer);05202(Transcriptional misregulation in cancers);05221(Acute myeloid leukemia);05221(Acute myeloid leukemia)","K05090","EC:2.7.10.1","colony stimulating factor 1 receptor [Source:HGNC Symbol;Acc:HGNC:2433]",{"v":20.3809380417395,"d":"20.38"},{"v":28.5032546878276,"d":"28.50"},{"v":0.715038975897838,"d":"0.72"},{"v":-0.483906211315253,"d":"-0.48"},{"v":0.48526478220699,"d":"0.49"},1,"down","no"]
["MSTRG.1294","ARL8A","ENST00000614750;ENST00000272217;ENST00000491358;ENST00000486225","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005525(GTP binding);GO:0007264(small GTPase mediated signal transduction);GO:0000166(nucleotide binding);GO:0005622(intracellular);GO:0005765(lysosomal membrane);GO:0051301(cell division);GO:0005515(protein binding);GO:0007049(cell cycle);GO:0003924(GTPase activity);GO:0005764(lysosome);GO:0030496(midbody);GO:0005886(plasma membrane);GO:0007059(chromosome segregation);GO:0005768(endosome);GO:0031902(late endosome membrane);GO:0070062(extracellular exosome);GO:0051233(spindle midzone);GO:0043014(alpha-tubulin binding);GO:0043312(neutrophil degranulation);GO:0035577(azurophil granule membrane);GO:0048487(beta-tubulin binding);GO:0101003(ficolin-1-rich granule membrane);GO:0101003(ficolin-1-rich granule membrane)","NA","NA","NA","ADP ribosylation factor like GTPase 8A [Source:HGNC Symbol;Acc:HGNC:25192]",{"v":10.5346441291139,"d":"10.53"},{"v":14.7521136167089,"d":"14.75"},{"v":0.714110832035749,"d":"0.71"},{"v":-0.485780092874607,"d":"-0.49"},{"v":0.485393905163777,"d":"0.49"},1,"down","no"]
["MSTRG.12478","LARP1","MSTRG.12478.2;ENST00000522272;ENST00000518194;ENST00000518742;ENST00000518677;ENST00000519931;ENST00000518297;ENST00000336314;ENST00000518595;ENST00000524187;ENST00000517616;ENST00000521577;ENST00000519194;ENST00000518892;ENST00000524248","GO:0003723(RNA binding);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0006412(translation);GO:0006413(translational initiation);GO:0005515(protein binding);GO:0045727(positive regulation of translation);GO:0045296(cadherin binding);GO:0006417(regulation of translation);GO:0008283(cell proliferation);GO:0017148(negative regulation of translation);GO:0010494(cytoplasmic stress granule);GO:0016239(positive regulation of macroautophagy);GO:0003730(mRNA 3'-UTR binding);GO:0008190(eukaryotic initiation factor 4E binding);GO:0031369(translation initiation factor binding);GO:0048027(mRNA 5'-UTR binding);GO:0031931(TORC1 complex);GO:0045070(positive regulation of viral genome replication);GO:0005844(polysome);GO:0008494(translation activator activity);GO:0048255(mRNA stabilization);GO:0031929(TOR signaling);GO:0038202(TORC1 signaling);GO:0000339(RNA cap binding);GO:0072752(cellular response to rapamycin);GO:1990928(response to amino acid starvation);GO:1990928(response to amino acid starvation)","NA","NA","NA","La ribonucleoprotein domain family member 1 [Source:HGNC Symbol;Acc:HGNC:29531]",{"v":9.95971195728585,"d":"9.96"},{"v":7.3977922435987,"d":"7.40"},{"v":1.34630868633868,"d":"1.35"},{"v":0.429009234013254,"d":"0.43"},{"v":0.487399587530006,"d":"0.49"},1,"up","no"]
["MSTRG.5840","ZNF48","ENST00000524644;ENST00000320159;ENST00000613509;ENST00000528032","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0003677(DNA binding)","NA","NA","NA","zinc finger protein 48 [Source:HGNC Symbol;Acc:HGNC:13114]",{"v":0.448052851762821,"d":"0.45"},{"v":0.321041355769231,"d":"0.32"},{"v":1.3956234725251,"d":"1.40"},{"v":0.480909767055064,"d":"0.48"},{"v":0.487804144307652,"d":"0.49"},1,"up","no"]
["ENSG00000057019","DCBLD2","ENST00000326840;ENST00000470393;ENST00000479144","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005515(protein binding);GO:0005887(integral component of plasma membrane);GO:0009986(cell surface);GO:0030308(negative regulation of cell growth);GO:0042060(wound healing);GO:0030522(intracellular receptor signaling pathway);GO:0030522(intracellular receptor signaling pathway)","NA","NA","NA","discoidin, CUB and LCCL domain containing 2 [Source:HGNC Symbol;Acc:HGNC:24627]",{"v":0.0637363516054639,"d":"0.06"},{"v":0.0913923069008338,"d":"0.09"},{"v":0.697392961911134,"d":"0.70"},{"v":-0.519956290375756,"d":"-0.52"},{"v":0.490539064502019,"d":"0.49"},1,"down","no"]
["MSTRG.601","USP1","ENST00000339950;ENST00000452143;ENST00000371146;ENST00000442679","GO:0016579(protein deubiquitination);GO:0006511(ubiquitin-dependent protein catabolic process);GO:0036459(thiol-dependent ubiquitinyl hydrolase activity);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0016787(hydrolase activity);GO:0008233(peptidase activity);GO:0008234(cysteine-type peptidase activity);GO:0006508(proteolysis);GO:0006281(DNA repair);GO:0006974(cellular response to DNA damage stimulus);GO:0004197(cysteine-type endopeptidase activity);GO:0005515(protein binding);GO:0004843(thiol-dependent ubiquitin-specific protease activity);GO:0036297(interstrand cross-link repair);GO:0009411(response to UV);GO:0001501(skeletal system development);GO:0006282(regulation of DNA repair);GO:0035520(monoubiquitinated protein deubiquitination);GO:0042769(DNA damage response, detection of DNA damage);GO:0042769(DNA damage response, detection of DNA damage)","03460(Fanconi anemia pathway);03460(Fanconi anemia pathway)","K11832","EC:3.4.19.12","ubiquitin specific peptidase 1 [Source:HGNC Symbol;Acc:HGNC:12607]",{"v":4.2855323687544,"d":"4.29"},{"v":5.96897932090077,"d":"5.97"},{"v":0.717967367343413,"d":"0.72"},{"v":-0.478009821927777,"d":"-0.48"},{"v":0.491923113568421,"d":"0.49"},1,"down","no"]
["ENSG00000152193","RNF219","ENST00000282003","GO:0046872(metal ion binding);GO:0005515(protein binding)","NA","NA","NA","ring finger protein 219 [Source:HGNC Symbol;Acc:HGNC:20308]",{"v":4.342416,"d":"4.34"},{"v":3.229022,"d":"3.23"},{"v":1.34480842806274,"d":"1.34"},{"v":0.427400671243987,"d":"0.43"},{"v":0.492185272819004,"d":"0.49"},1,"up","no"]
["MSTRG.2525","ARL2;SNX15","ENST00000246747;ENST00000377244;ENST00000531533;ENST00000529673;ENST00000529254;ENST00000524831;ENST00000529384;ENST00000352068;ENST00000533729;ENST00000526702;ENST00000524585","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005794(Golgi apparatus);GO:0005525(GTP binding);GO:0007264(small GTPase mediated signal transduction);GO:0000166(nucleotide binding);GO:0005730(nucleolus);GO:0005829(cytosol);GO:0005622(intracellular);GO:0005925(focal adhesion);GO:0005739(mitochondrion);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0007049(cell cycle);GO:0003924(GTPase activity);GO:0005813(centrosome);GO:0005815(microtubule organizing center);GO:0005758(mitochondrial intermembrane space);GO:0070062(extracellular exosome);GO:0005759(mitochondrial matrix);GO:0007098(centrosome cycle);GO:0016328(lateral plasma membrane);GO:0005095(GTPase inhibitor activity);GO:0050796(regulation of insulin secretion);GO:0070830(bicellular tight junction assembly);GO:0010811(positive regulation of cell-substrate adhesion);GO:0031113(regulation of microtubule polymerization);GO:0031116(positive regulation of microtubule polymerization);GO:0051457(maintenance of protein location in nucleus);GO:0034260(negative regulation of GTPase activity);GO:0007021(tubulin complex assembly);GO:0006810(transport);GO:0016020(membrane);GO:0006886(intracellular protein transport);GO:0015031(protein transport);GO:0030659(cytoplasmic vesicle membrane);GO:0031410(cytoplasmic vesicle);GO:0035091(phosphatidylinositol binding);GO:0008289(lipid binding);GO:0007165(signal transduction);GO:0007021(tubulin complex assembly)","NA","NA","NA","ADP ribosylation factor like GTPase 2 [Source:HGNC Symbol;Acc:HGNC:693];sorting nexin 15 [Source:HGNC Symbol;Acc:HGNC:14978]",{"v":3.51101620256736,"d":"3.51"},{"v":2.6168219507688,"d":"2.62"},{"v":1.3417100087898,"d":"1.34"},{"v":0.424072887566573,"d":"0.42"},{"v":0.492771257994429,"d":"0.49"},1,"up","no"]
["MSTRG.5716","SMG1","ENST00000446231;ENST00000569122;ENST00000569764;ENST00000566328;ENST00000561940;ENST00000568239;ENST00000532700;ENST00000563235;ENST00000561947;ENST00000568038;ENST00000563448;ENST00000567737","GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0004674(protein serine/threonine kinase activity);GO:0005524(ATP binding);GO:0005654(nucleoplasm);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0000184(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay);GO:0005515(protein binding);GO:0006281(DNA repair);GO:0006974(cellular response to DNA damage stimulus);GO:0006406(mRNA export from nucleus);GO:0005829(cytosol);GO:0004672(protein kinase activity);GO:0046777(protein autophosphorylation);GO:0006950(response to stress);GO:0042162(telomeric DNA binding);GO:0032204(regulation of telomere maintenance);GO:0018105(peptidyl-serine phosphorylation);GO:0046854(phosphatidylinositol phosphorylation);GO:0006468(protein phosphorylation);GO:0006468(protein phosphorylation)","03015(mRNA surveillance pathway);03015(mRNA surveillance pathway)","K08873","EC:2.7.11.1","SMG1, nonsense mediated mRNA decay associated PI3K related kinase [Source:HGNC Symbol;Acc:HGNC:30045]",{"v":3.56830651123595,"d":"3.57"},{"v":2.66398154825304,"d":"2.66"},{"v":1.33946367367895,"d":"1.34"},{"v":0.421655455749998,"d":"0.42"},{"v":0.493882437916054,"d":"0.49"},1,"up","no"]
["MSTRG.11477","RPL35A","ENST00000442341;ENST00000429437;ENST00000448864;ENST00000464167;ENST00000439255;ENST00000496582;ENST00000474640;MSTRG.11477.1;ENST00000485439;ENST00000329092","GO:0003723(RNA binding);GO:0016020(membrane);GO:0006412(translation);GO:0030529(intracellular ribonucleoprotein complex);GO:0005622(intracellular);GO:0003735(structural constituent of ribosome);GO:0005840(ribosome);GO:0000049(tRNA binding);GO:0006364(rRNA processing);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0031012(extracellular matrix);GO:0042273(ribosomal large subunit biogenesis);GO:0005515(protein binding);GO:0002181(cytoplasmic translation);GO:0006413(translational initiation);GO:0000184(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay);GO:0019083(viral transcription);GO:0006614(SRP-dependent cotranslational protein targeting to membrane);GO:0022625(cytosolic large ribosomal subunit);GO:0022625(cytosolic large ribosomal subunit)","03010(Ribosome);03010(Ribosome)","K02917","NA","ribosomal protein L35a [Source:HGNC Symbol;Acc:HGNC:10345]",{"v":88.5283697622052,"d":"88.53"},{"v":66.1604884805712,"d":"66.16"},{"v":1.33808518944358,"d":"1.34"},{"v":0.420169968352625,"d":"0.42"},{"v":0.495275318356721,"d":"0.50"},1,"up","no"]
["MSTRG.3937","HMGB1","ENST00000399489;ENST00000341423;ENST00000339872;MSTRG.3937.2;ENST00000490788;ENST00000405805;ENST00000326004;ENST00000468384;ENST00000399494","GO:0005634(nucleus);GO:0003723(RNA binding);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0003677(DNA binding);GO:0016829(lyase activity);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0005694(chromosome);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0045859(regulation of protein kinase activity);GO:0006281(DNA repair);GO:0006310(DNA recombination);GO:0006974(cellular response to DNA damage stimulus);GO:0005125(cytokine activity);GO:0005615(extracellular space);GO:0006914(autophagy);GO:0002376(immune system process);GO:0045087(innate immune response);GO:0006935(chemotaxis);GO:0006954(inflammatory response);GO:0000400(four-way junction DNA binding);GO:0000405(bubble DNA binding);GO:0003690(double-stranded DNA binding);GO:0003725(double-stranded RNA binding);GO:0003727(single-stranded RNA binding);GO:0008301(DNA binding, bending);GO:0010858(calcium-dependent protein kinase regulator activity);GO:0030295(protein kinase activator activity);GO:0097100(supercoiled DNA binding);GO:0001654(eye development);GO:0001773(myeloid dendritic cell activation);GO:0001934(positive regulation of protein phosphorylation);GO:0001935(endothelial cell proliferation);GO:0002270(plasmacytoid dendritic cell activation);GO:0002281(macrophage activation involved in immune response);GO:0002643(regulation of tolerance induction);GO:0002840(regulation of T cell mediated immune response to tumor cell);GO:0006284(base-excision repair);GO:0010506(regulation of autophagy);GO:0030324(lung development);GO:0031497(chromatin assembly);GO:0032147(activation of protein kinase activity);GO:0032392(DNA geometric change);GO:0032727(positive regulation of interferon-alpha production);GO:0032728(positive regulation of interferon-beta production);GO:0032755(positive regulation of interleukin-6 production);GO:0032760(positive regulation of tumor necrosis factor production);GO:0034137(positive regulation of toll-like receptor 2 signaling pathway);GO:0034145(positive regulation of toll-like receptor 4 signaling pathway);GO:0035767(endothelial cell chemotaxis);GO:0045089(positive regulation of innate immune response);GO:0045639(positive regulation of myeloid cell differentiation);GO:0045819(positive regulation of glycogen catabolic process);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0050718(positive regulation of interleukin-1 beta secretion);GO:0051384(response to glucocorticoid);GO:0070374(positive regulation of ERK1 and ERK2 cascade);GO:0090303(positive regulation of wound healing);GO:1901224(positive regulation of NIK/NF-kappaB signaling);GO:1903672(positive regulation of sprouting angiogenesis);GO:2000426(negative regulation of apoptotic cell clearance);GO:2000819(regulation of nucleotide-excision repair);GO:0005769(early endosome);GO:0043005(neuron projection);GO:0002250(adaptive immune response);GO:0050918(positive chemotaxis);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0005768(endosome);GO:0005654(nucleoplasm);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0043065(positive regulation of apoptotic process);GO:0043312(neutrophil degranulation);GO:0032689(negative regulation of interferon-gamma production);GO:2000778(positive regulation of interleukin-6 secretion);GO:2001200(positive regulation of dendritic cell differentiation);GO:0001530(lipopolysaccharide binding);GO:0002224(toll-like receptor signaling pathway);GO:0009986(cell surface);GO:0008134(transcription factor binding);GO:0034774(secretory granule lumen);GO:1904813(ficolin-1-rich granule lumen);GO:0006309(apoptotic DNA fragmentation);GO:0070491(repressing transcription factor binding);GO:0007204(positive regulation of cytosolic calcium ion concentration);GO:0043280(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process);GO:0001786(phosphatidylserine binding);GO:0043277(apoptotic cell clearance);GO:0070182(DNA polymerase binding);GO:0031175(neuron projection development);GO:0002218(activation of innate immune response);GO:0046330(positive regulation of JNK cascade);GO:0005793(endoplasmic reticulum-Golgi intermediate compartment);GO:0003697(single-stranded DNA binding);GO:0017053(transcriptional repressor complex);GO:0042056(chemoattractant activity);GO:0043410(positive regulation of MAPK cascade);GO:0003684(damaged DNA binding);GO:0090026(positive regulation of monocyte chemotaxis);GO:0000793(condensed chromosome);GO:0043388(positive regulation of DNA binding);GO:0042104(positive regulation of activated T cell proliferation);GO:0002407(dendritic cell chemotaxis);GO:0032735(positive regulation of interleukin-12 production);GO:0050716(positive regulation of interleukin-1 secretion);GO:0002437(inflammatory response to antigenic stimulus);GO:0050786(RAGE receptor binding);GO:0019958(C-X-C chemokine binding);GO:0006265(DNA topological change);GO:0017055(negative regulation of RNA polymerase II transcriptional preinitiation complex assembly);GO:0032072(regulation of restriction endodeoxyribonuclease activity);GO:0032425(positive regulation of mismatch repair);GO:0032733(positive regulation of interleukin-10 production);GO:0033151(V(D)J recombination);GO:0034165(positive regulation of toll-like receptor 9 signaling pathway);GO:0035711(T-helper 1 cell activation);GO:0043371(negative regulation of CD4-positive, alpha-beta T cell differentiation);GO:0043537(negative regulation of blood vessel endothelial cell migration);GO:0045063(T-helper 1 cell differentiation);GO:0051103(DNA ligation involved in DNA repair);GO:0051106(positive regulation of DNA ligation);GO:0097350(neutrophil clearance);GO:1990774(tumor necrosis factor secretion);GO:1990774(tumor necrosis factor secretion)","03410(Base excision repair);04140(Autophagy - animal);04217(Necroptosis);04217(Necroptosis)","K10802","NA","high mobility group box 1 [Source:HGNC Symbol;Acc:HGNC:4983]",{"v":13.882866553222,"d":"13.88"},{"v":19.2596062047733,"d":"19.26"},{"v":0.720828162612238,"d":"0.72"},{"v":-0.472272716827892,"d":"-0.47"},{"v":0.496167104607619,"d":"0.50"},1,"down","no"]
["ENSG00000187912","CLEC17A","ENST00000339847;ENST00000551730;ENST00000417570;ENST00000547437","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0046872(metal ion binding);GO:0030246(carbohydrate binding);GO:0042806(fucose binding);GO:0009986(cell surface);GO:0005537(mannose binding);GO:0005537(mannose binding)","NA","NA","NA","C-type lectin domain containing 17A [Source:HGNC Symbol;Acc:HGNC:34520]",{"v":0.737923207327971,"d":"0.74"},{"v":1.04940491867739,"d":"1.05"},{"v":0.703182531541788,"d":"0.70"},{"v":-0.508028863386509,"d":"-0.51"},{"v":0.497917402401282,"d":"0.50"},1,"down","no"]
["ENSG00000104341","LAPTM4B","ENST00000445593;ENST00000619747;ENST00000517924;ENST00000521545","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005515(protein binding);GO:0012505(endomembrane system);GO:0012505(endomembrane system)","04142(Lysosome);04142(Lysosome)","K12387","NA","lysosomal protein transmembrane 4 beta [Source:HGNC Symbol;Acc:HGNC:13646]",{"v":0.512135092899593,"d":"0.51"},{"v":0.717917799186738,"d":"0.72"},{"v":0.713361743475009,"d":"0.71"},{"v":-0.487294246588672,"d":"-0.49"},{"v":0.499930289566641,"d":"0.50"},1,"down","no"]
["MSTRG.587","YIPF1","ENST00000469457;ENST00000465897;MSTRG.587.4;ENST00000480151;ENST00000464950;ENST00000371399;ENST00000072644;ENST00000472983","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005515(protein binding);GO:0017137(Rab GTPase binding);GO:0005794(Golgi apparatus);GO:0030133(transport vesicle);GO:0030133(transport vesicle)","NA","NA","NA","Yip1 domain family member 1 [Source:HGNC Symbol;Acc:HGNC:25231]",{"v":7.23023428233591,"d":"7.23"},{"v":10.0421548822394,"d":"10.04"},{"v":0.719988325924283,"d":"0.72"},{"v":-0.473954580370863,"d":"-0.47"},{"v":0.500274581418956,"d":"0.50"},1,"down","no"]
["MSTRG.2304","FANCF","ENST00000327470","GO:0005634(nucleus);GO:0005515(protein binding);GO:0006281(DNA repair);GO:0006974(cellular response to DNA damage stimulus);GO:0043240(Fanconi anaemia nuclear complex);GO:0003674(molecular_function);GO:0008150(biological_process);GO:0005654(nucleoplasm);GO:0061630(ubiquitin protein ligase activity);GO:0001541(ovarian follicle development);GO:0007283(spermatogenesis);GO:0016567(protein ubiquitination);GO:0036297(interstrand cross-link repair)","03460(Fanconi anemia pathway)","K10893","NA","Fanconi anemia complementation group F [Source:HGNC Symbol;Acc:HGNC:3587]",{"v":1.891243,"d":"1.89"},{"v":1.415241,"d":"1.42"},{"v":1.33633988840063,"d":"1.34"},{"v":0.418286993549686,"d":"0.42"},{"v":0.502420350511149,"d":"0.50"},1,"up","no"]
["ENSG00000206127","GOLGA8O","ENST00000509311;ENST00000562377","GO:0005515(protein binding);GO:0005794(Golgi apparatus);GO:0005794(Golgi apparatus)","NA","NA","NA","golgin A8 family member O [Source:HGNC Symbol;Acc:HGNC:44406]",{"v":0.760481755771007,"d":"0.76"},{"v":1.06263724007387,"d":"1.06"},{"v":0.715655095729698,"d":"0.72"},{"v":-0.482663635283671,"d":"-0.48"},{"v":0.50250246004414,"d":"0.50"},1,"down","no"]
["ENSG00000042980","ADAM28","ENST00000265769;ENST00000520665;ENST00000520448;ENST00000523236;ENST00000521629;ENST00000523440;ENST00000518737;ENST00000521110;ENST00000437154;ENST00000518326;ENST00000518516","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0046872(metal ion binding);GO:0016787(hydrolase activity);GO:0005739(mitochondrion);GO:0005886(plasma membrane);GO:0008233(peptidase activity);GO:0006508(proteolysis);GO:0005576(extracellular region);GO:0004222(metalloendopeptidase activity);GO:0008237(metallopeptidase activity);GO:0007283(spermatogenesis);GO:0007283(spermatogenesis)","NA","NA","NA","ADAM metallopeptidase domain 28 [Source:HGNC Symbol;Acc:HGNC:206]",{"v":0.844935690942145,"d":"0.84"},{"v":1.17157312918404,"d":"1.17"},{"v":0.721197567522408,"d":"0.72"},{"v":-0.471533564075618,"d":"-0.47"},{"v":0.504584409113994,"d":"0.50"},1,"down","no"]
["MSTRG.2710","XRRA1","ENST00000431210;ENST00000527087;ENST00000529926;ENST00000531849;ENST00000531852;ENST00000530562;ENST00000528219;ENST00000533990;ENST00000530280;ENST00000340360;ENST00000534041;ENST00000533598","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005654(nucleoplasm);GO:0016604(nuclear body);GO:0003674(molecular_function);GO:0010165(response to X-ray);GO:0010165(response to X-ray)","NA","NA","NA","X-ray radiation resistance associated 1 [Source:HGNC Symbol;Acc:HGNC:18868]",{"v":0.698120291877614,"d":"0.70"},{"v":0.522060665639445,"d":"0.52"},{"v":1.33723978423566,"d":"1.34"},{"v":0.419258182342614,"d":"0.42"},{"v":0.50505442628622,"d":"0.51"},1,"up","no"]
["MSTRG.4546","MLH3","ENST00000355774;MSTRG.4546.3;ENST00000554697;ENST00000556740;ENST00000380968;ENST00000557648;ENST00000556453;MSTRG.4546.6;ENST00000556257;ENST00000553713;ENST00000555144;ENST00000555415","GO:0005634(nucleus);GO:0005524(ATP binding);GO:0006281(DNA repair);GO:0006974(cellular response to DNA damage stimulus);GO:0030983(mismatched DNA binding);GO:0006298(mismatch repair);GO:0005515(protein binding);GO:0007131(reciprocal meiotic recombination);GO:0016887(ATPase activity);GO:0000795(synaptonemal complex);GO:0032300(mismatch repair complex);GO:0003697(single-stranded DNA binding);GO:0003696(satellite DNA binding);GO:0005712(chiasma);GO:0003682(chromatin binding);GO:0019237(centromeric DNA binding);GO:0007130(synaptonemal complex assembly);GO:0007140(male meiotic nuclear division);GO:0007144(female meiosis I);GO:0008104(protein localization);GO:0000793(condensed chromosome);GO:0000794(condensed nuclear chromosome);GO:0001673(male germ cell nucleus);GO:0001673(male germ cell nucleus)","03430(Mismatch repair);03430(Mismatch repair)","K08739","NA","mutL homolog 3 [Source:HGNC Symbol;Acc:HGNC:7128]",{"v":1.50321551366702,"d":"1.50"},{"v":1.12758102177257,"d":"1.13"},{"v":1.33313303846135,"d":"1.33"},{"v":0.414820759685106,"d":"0.41"},{"v":0.506467354545109,"d":"0.51"},1,"up","no"]
["ENSG00000114648","KLHL18","ENST00000232766;ENST00000433449;ENST00000442272;ENST00000461084;ENST00000483201","GO:0016567(protein ubiquitination);GO:0005515(protein binding);GO:0004842(ubiquitin-protein transferase activity);GO:0031463(Cul3-RING ubiquitin ligase complex);GO:0031463(Cul3-RING ubiquitin ligase complex)","NA","NA","NA","kelch like family member 18 [Source:HGNC Symbol;Acc:HGNC:29120]",{"v":2.19701781143828,"d":"2.20"},{"v":3.02902677137599,"d":"3.03"},{"v":0.725321358067841,"d":"0.73"},{"v":-0.463307763248841,"d":"-0.46"},{"v":0.508681726727059,"d":"0.51"},1,"down","no"]
["MSTRG.3983","TPT1;SNORA31","ENST00000616577;ENST00000379056;ENST00000530705;ENST00000379055;ENST00000309246;ENST00000379060;ENST00000529421;ENST00000527226;ENST00000528619;ENST00000533567;ENST00000490277;ENST00000362607;ENST00000530245;ENST00000442760;ENST00000484604","GO:0003723(RNA binding);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005515(protein binding);GO:0006816(calcium ion transport);GO:0005509(calcium ion binding);GO:0070062(extracellular exosome);GO:0008017(microtubule binding);GO:0009615(response to virus);GO:0030154(cell differentiation);GO:0042981(regulation of apoptotic process);GO:0043066(negative regulation of apoptotic process);GO:0005615(extracellular space);GO:0005634(nucleus);GO:0006874(cellular calcium ion homeostasis);GO:0045298(tubulin complex);GO:1902230(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage);GO:0005771(multivesicular body);GO:0005771(multivesicular body)","NA","NA","NA","tumor protein, translationally-controlled 1 [Source:HGNC Symbol;Acc:HGNC:12022];small nucleolar RNA, H/ACA box 31 [Source:HGNC Symbol;Acc:HGNC:32621]",{"v":414.636294574744,"d":"414.64"},{"v":569.703068054607,"d":"569.70"},{"v":0.727811236809068,"d":"0.73"},{"v":-0.458363769506667,"d":"-0.46"},{"v":0.509270162270998,"d":"0.51"},1,"down","no"]
["MSTRG.3395","ZNF740","ENST00000416904;ENST00000549739;ENST00000552593","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated)","NA","NA","NA","zinc finger protein 740 [Source:HGNC Symbol;Acc:HGNC:27465]",{"v":4.54808875339292,"d":"4.55"},{"v":3.43382301489573,"d":"3.43"},{"v":1.32449713734912,"d":"1.32"},{"v":0.405444725597538,"d":"0.41"},{"v":0.510782123139019,"d":"0.51"},1,"up","no"]
["ENSG00000159733","ZFYVE28","ENST00000515169;ENST00000290974;ENST00000508184;ENST00000504743;ENST00000515312;ENST00000505421;ENST00000509171;ENST00000503000;ENST00000514248;ENST00000508471","GO:0046872(metal ion binding);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005829(cytosol);GO:0005515(protein binding);GO:0005768(endosome);GO:0032266(phosphatidylinositol-3-phosphate binding);GO:0031901(early endosome membrane);GO:0007175(negative regulation of epidermal growth factor-activated receptor activity);GO:0042059(negative regulation of epidermal growth factor receptor signaling pathway);GO:0042059(negative regulation of epidermal growth factor receptor signaling pathway)","NA","NA","NA","zinc finger FYVE-type containing 28 [Source:HGNC Symbol;Acc:HGNC:29334]",{"v":0.938184561201164,"d":"0.94"},{"v":0.706097536159601,"d":"0.71"},{"v":1.32868975340696,"d":"1.33"},{"v":0.410004277320618,"d":"0.41"},{"v":0.511196909651317,"d":"0.51"},1,"up","no"]
["ENSG00000198848","CES1","ENST00000360526;ENST00000361503;ENST00000569260;ENST00000563005;ENST00000563241;ENST00000422046;ENST00000565403","GO:0005829(cytosol);GO:0005783(endoplasmic reticulum);GO:0016787(hydrolase activity);GO:0005788(endoplasmic reticulum lumen);GO:0052689(carboxylic ester hydrolase activity);GO:0006805(xenobiotic metabolic process);GO:0030855(epithelial cell differentiation);GO:0047374(methylumbelliferyl-acetate deacetylase activity);GO:0008152(metabolic process);GO:0051791(medium-chain fatty acid metabolic process);GO:0006695(cholesterol biosynthetic process);GO:0009636(response to toxic substance);GO:0004771(sterol esterase activity);GO:0090122(cholesterol ester hydrolysis involved in cholesterol transport);GO:0090122(cholesterol ester hydrolysis involved in cholesterol transport)","00983(Drug metabolism - other enzymes);00983(Drug metabolism - other enzymes)","K01044","EC:3.1.1.1","carboxylesterase 1 [Source:HGNC Symbol;Acc:HGNC:1863]",{"v":3.76281054102826,"d":"3.76"},{"v":5.18034391726251,"d":"5.18"},{"v":0.726363075719627,"d":"0.73"},{"v":-0.461237229029111,"d":"-0.46"},{"v":0.51250038462346,"d":"0.51"},1,"down","no"]
["MSTRG.381","ZBTB8OS","ENST00000479075;ENST00000468695;ENST00000466361;ENST00000476493;ENST00000373506;ENST00000498691;ENST00000467652;ENST00000483138;ENST00000436661;ENST00000465588;ENST00000473294;ENST00000473383;ENST00000373501;ENST00000492007","GO:0046872(metal ion binding);GO:0008033(tRNA processing);GO:0005654(nucleoplasm);GO:0070062(extracellular exosome);GO:0006388(tRNA splicing, via endonucleolytic cleavage and ligation);GO:0072669(tRNA-splicing ligase complex);GO:0072669(tRNA-splicing ligase complex)","NA","NA","NA","zinc finger and BTB domain containing 8 opposite strand [Source:HGNC Symbol;Acc:HGNC:24094]",{"v":1.0311767068819,"d":"1.03"},{"v":1.41261001359388,"d":"1.41"},{"v":0.72997975163608,"d":"0.73"},{"v":-0.454071648181499,"d":"-0.45"},{"v":0.51286026113759,"d":"0.51"},1,"down","no"]
["MSTRG.12996","SRSF3","ENST00000339436;ENST00000373715;MSTRG.12996.5;ENST00000477442;ENST00000620941;ENST00000620242;ENST00000614136;ENST00000620389;ENST00000613941","GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0006397(mRNA processing);GO:0006810(transport);GO:0008380(RNA splicing);GO:0051028(mRNA transport);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016607(nuclear speck);GO:0005515(protein binding);GO:0005654(nucleoplasm);GO:1990825(sequence-specific mRNA binding);GO:0006369(termination of RNA polymerase II transcription);GO:0006405(RNA export from nucleus);GO:0031124(mRNA 3'-end processing);GO:0000398(mRNA splicing, via spliceosome);GO:0006406(mRNA export from nucleus);GO:0048024(regulation of mRNA splicing, via spliceosome);GO:0048024(regulation of mRNA splicing, via spliceosome)","03040(Spliceosome);05168(Herpes simplex infection);05168(Herpes simplex infection)","K12892","NA","serine and arginine rich splicing factor 3 [Source:HGNC Symbol;Acc:HGNC:10785]",{"v":5.64604786185948,"d":"5.65"},{"v":7.73640989593238,"d":"7.74"},{"v":0.729802057777218,"d":"0.73"},{"v":-0.454422876082258,"d":"-0.45"},{"v":0.514174491560626,"d":"0.51"},1,"down","no"]
["MSTRG.7394","MYL12A","ENST00000578611;ENST00000217652;ENST00000579226;ENST00000578562;ENST00000608786;ENST00000577510;ENST00000585090;ENST00000580353;ENST00000580887;ENST00000583449","GO:0046872(metal ion binding);GO:0005509(calcium ion binding);GO:0016459(myosin complex);GO:0005515(protein binding);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0070527(platelet aggregation);GO:0048013(ephrin receptor signaling pathway);GO:0006936(muscle contraction);GO:0006936(muscle contraction)","04510(Focal adhesion);04530(Tight junction);04810(Regulation of actin cytoskeleton);04611(Platelet activation);04670(Leukocyte transendothelial migration);04670(Leukocyte transendothelial migration)","K12757","NA","myosin light chain 12A [Source:HGNC Symbol;Acc:HGNC:16701]",{"v":20.6414256502311,"d":"20.64"},{"v":28.2452766973806,"d":"28.25"},{"v":0.730792120444879,"d":"0.73"},{"v":-0.452467016280995,"d":"-0.45"},{"v":0.515642311546968,"d":"0.52"},1,"down","no"]
["ENSG00000197557","TTC30A","ENST00000355689","GO:0042995(cell projection);GO:0005929(cilium);GO:0030030(cell projection organization);GO:0060271(cilium assembly);GO:0030992(intraciliary transport particle B);GO:0042073(intraciliary transport)","NA","NA","NA","tetratricopeptide repeat domain 30A [Source:HGNC Symbol;Acc:HGNC:25853]",{"v":0.111063,"d":"0.11"},{"v":0.158977,"d":"0.16"},{"v":0.698610490825717,"d":"0.70"},{"v":-0.517439787470078,"d":"-0.52"},{"v":0.516266566391843,"d":"0.52"},1,"down","no"]
["ENSG00000102471","NDFIP2","ENST00000620924;ENST00000612570;ENST00000218652","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0043231(intracellular membrane-bounded organelle);GO:0005794(Golgi apparatus);GO:0004871(signal transducer activity);GO:0000139(Golgi membrane);GO:0048471(perinuclear region of cytoplasm);GO:0007165(signal transduction);GO:0005515(protein binding);GO:0005768(endosome);GO:0010008(endosome membrane);GO:0031398(positive regulation of protein ubiquitination);GO:0043123(positive regulation of I-kappaB kinase/NF-kappaB signaling);GO:0005783(endoplasmic reticulum);GO:0010629(negative regulation of gene expression);GO:0032585(multivesicular body membrane);GO:0032410(negative regulation of transporter activity);GO:0051224(negative regulation of protein transport);GO:0005739(mitochondrion);GO:0050699(WW domain binding);GO:0005622(intracellular);GO:0030001(metal ion transport);GO:0007034(vacuolar transport);GO:0007034(vacuolar transport)","NA","NA","NA","Nedd4 family interacting protein 2 [Source:HGNC Symbol;Acc:HGNC:18537]",{"v":0.211595124818878,"d":"0.21"},{"v":0.152940887600911,"d":"0.15"},{"v":1.38350919847557,"d":"1.38"},{"v":0.468332235961577,"d":"0.47"},{"v":0.517203104723098,"d":"0.52"},1,"up","no"]
["MSTRG.4191","PABPN1;BCL2L2;BCL2L2-PABPN1","ENST00000397276;ENST00000250405;ENST00000216727;ENST00000556809;ENST00000553781;ENST00000553960;ENST00000553824;ENST00000555295;ENST00000557236;ENST00000556100;ENST00000557579;ENST00000554635;ENST00000557702;ENST00000557008;ENST00000554062;ENST00000556821","GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0006397(mRNA processing);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016607(nuclear speck);GO:0030529(intracellular ribonucleoprotein complex);GO:0005515(protein binding);GO:0005654(nucleoplasm);GO:0071222(cellular response to lipopolysaccharide);GO:1904247(positive regulation of polynucleotide adenylyltransferase activity);GO:0006369(termination of RNA polymerase II transcription);GO:0031124(mRNA 3'-end processing);GO:0006936(muscle contraction);GO:0000165(MAPK cascade);GO:0000398(mRNA splicing, via spliceosome);GO:0006396(RNA processing);GO:0070063(RNA polymerase binding);GO:0042405(nuclear inclusion body);GO:0016973(poly(A)+ mRNA export from nucleus);GO:0046778(modification by virus of host mRNA processing);GO:0042981(regulation of apoptotic process);GO:0006915(apoptotic process);GO:0016020(membrane);GO:0005739(mitochondrion);GO:0031966(mitochondrial membrane);GO:0070062(extracellular exosome);GO:0043066(negative regulation of apoptotic process);GO:0007283(spermatogenesis);GO:0042803(protein homodimerization activity);GO:0046982(protein heterodimerization activity);GO:0097718(disordered domain specific binding);GO:0008630(intrinsic apoptotic signaling pathway in response to DNA damage);GO:0097192(extrinsic apoptotic signaling pathway in absence of ligand);GO:0005741(mitochondrial outer membrane);GO:2001243(negative regulation of intrinsic apoptotic signaling pathway);GO:0051400(BH domain binding);GO:0060011(Sertoli cell proliferation);GO:0005829(cytosol);GO:0097136(Bcl-2 family protein complex);GO:0016021(integral component of membrane);GO:0046778(modification by virus of host mRNA processing)","03015(mRNA surveillance pathway);05164(Influenza A);05206(MicroRNAs in cancer);05164(Influenza A)","K02163;K14396","NA","poly(A) binding protein nuclear 1 [Source:HGNC Symbol;Acc:HGNC:8565];BCL2 like 2 [Source:HGNC Symbol;Acc:HGNC:995];BCL2L2-PABPN1 readthrough [Source:HGNC Symbol;Acc:HGNC:42959]",{"v":8.18791214176998,"d":"8.19"},{"v":6.21781281121885,"d":"6.22"},{"v":1.31684764246947,"d":"1.32"},{"v":0.39708843734169,"d":"0.40"},{"v":0.51767539463638,"d":"0.52"},1,"up","no"]
["MSTRG.9406","SMARCAL1","ENST00000392128;ENST00000357276;ENST00000430374;ENST00000445153;ENST00000444508;ENST00000486983;ENST00000425815;ENST00000479008","GO:0005634(nucleus);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0005654(nucleoplasm);GO:0016787(hydrolase activity);GO:0004386(helicase activity);GO:0005515(protein binding);GO:0006974(cellular response to DNA damage stimulus);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0031297(replication fork processing);GO:0008094(DNA-dependent ATPase activity);GO:0035861(site of double-strand break);GO:0090656(t-circle formation);GO:0005662(DNA replication factor A complex);GO:0006259(DNA metabolic process);GO:0000733(DNA strand renaturation);GO:0036310(annealing helicase activity);GO:0036310(annealing helicase activity)","NA","NA","NA","SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a like 1 [Source:HGNC Symbol;Acc:HGNC:11102]",{"v":1.97290317164179,"d":"1.97"},{"v":1.49693992989002,"d":"1.50"},{"v":1.31795747594677,"d":"1.32"},{"v":0.398303822371444,"d":"0.40"},{"v":0.519431305758894,"d":"0.52"},1,"up","no"]
["MSTRG.12670","TMEM14C","ENST00000229563;ENST00000541412;ENST00000495549","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005739(mitochondrion);GO:0005515(protein binding);GO:0006783(heme biosynthetic process);GO:0031966(mitochondrial membrane);GO:0031966(mitochondrial membrane)","NA","NA","NA","transmembrane protein 14C [Source:HGNC Symbol;Acc:HGNC:20952]",{"v":3.0999191014383,"d":"3.10"},{"v":4.27163839212718,"d":"4.27"},{"v":0.725697921235933,"d":"0.73"},{"v":-0.462558957447108,"d":"-0.46"},{"v":0.520281605041726,"d":"0.52"},1,"down","no"]
["MSTRG.273","MTFR1L;SELENON;AL020996.2","ENST00000374303;ENST00000361547;ENST00000374300;ENST00000474295;ENST00000374315;ENST00000466284;ENST00000494293;ENST00000424294;ENST00000529116;ENST00000533762;ENST00000526894;ENST00000527604;ENST00000464008;ENST00000497956;ENST00000374301;ENST00000559265;ENST00000530599;ENST00000374307;ENST00000526158;ENST00000494537;ENST00000630065;ENST00000478284;ENST00000524618","GO:0005515(protein binding);GO:0009060(aerobic respiration);GO:0005739(mitochondrion);GO:0000266(mitochondrial fission);GO:0016020(membrane);GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0005509(calcium ion binding);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0003674(molecular_function);GO:0008150(biological_process);GO:0048741(skeletal muscle fiber development);GO:0055074(calcium ion homeostasis);GO:0060314(regulation of ryanodine-sensitive calcium-release channel activity);GO:1902884(positive regulation of response to oxidative stress);GO:0000266(mitochondrial fission)","NA","NA","NA","mitochondrial fission regulator 1 like [Source:HGNC Symbol;Acc:HGNC:28836];selenoprotein N [Source:HGNC Symbol;Acc:HGNC:15999]",{"v":5.39071122712626,"d":"5.39"},{"v":4.0961684473196,"d":"4.10"},{"v":1.31603748636211,"d":"1.32"},{"v":0.396200583768041,"d":"0.40"},{"v":0.521058923613973,"d":"0.52"},1,"up","no"]
["ENSG00000184083","FAM120C","ENST00000375180;ENST00000328235;ENST00000477084;ENST00000497680","GO:0005634(nucleus);GO:0003723(RNA binding);GO:0003723(RNA binding)","NA","NA","NA","family with sequence similarity 120C [Source:HGNC Symbol;Acc:HGNC:16949]",{"v":0.312613034890328,"d":"0.31"},{"v":0.234902892601432,"d":"0.23"},{"v":1.33081815821123,"d":"1.33"},{"v":0.412313456171538,"d":"0.41"},{"v":0.522764808399885,"d":"0.52"},1,"up","no"]
["MSTRG.13058","ZNF318;CRIP3","ENST00000361428;ENST00000485819;ENST00000605935;ENST00000451294;ENST00000487744;ENST00000416431;ENST00000274990;ENST00000372569;ENST00000477866;ENST00000606599;ENST00000607252","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0051321(meiotic cell cycle);GO:0005737(cytoplasm);GO:0051321(meiotic cell cycle)","NA","NA","NA","zinc finger protein 318 [Source:HGNC Symbol;Acc:HGNC:13578];cysteine rich protein 3 [Source:HGNC Symbol;Acc:HGNC:17751]",{"v":2.72735251282493,"d":"2.73"},{"v":2.07504539369943,"d":"2.08"},{"v":1.31435799963998,"d":"1.31"},{"v":0.394358284762122,"d":"0.39"},{"v":0.522828367930898,"d":"0.52"},1,"up","no"]
["MSTRG.2153","HBG2;HBG1;HBE1;AC015691.1;OR51B5","ENST00000444587;ENST00000380252;MSTRG.2153.3;ENST00000336906;ENST00000330597;MSTRG.2153.2;ENST00000380237;ENST00000394793;ENST00000300773;ENST00000380259;ENST00000632727","GO:0006810(transport);GO:0046872(metal ion binding);GO:0005506(iron ion binding);GO:0020037(heme binding);GO:0005344(oxygen transporter activity);GO:0019825(oxygen binding);GO:0015671(oxygen transport);GO:0005833(hemoglobin complex);GO:0005515(protein binding);GO:0005829(cytosol);GO:0072562(blood microparticle);GO:0007596(blood coagulation);GO:0031721(hemoglobin alpha binding);GO:0014070(response to organic cyclic compound);GO:0051291(protein heterooligomerization);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0004930(G-protein coupled receptor activity);GO:0007186(G-protein coupled receptor signaling pathway);GO:0005886(plasma membrane);GO:0004871(signal transducer activity);GO:0007165(signal transduction);GO:0004984(olfactory receptor activity);GO:0007608(sensory perception of smell);GO:0050896(response to stimulus);GO:0050911(detection of chemical stimulus involved in sensory perception of smell);GO:0007596(blood coagulation)","04740(Olfactory transduction)","K04257","NA","hemoglobin subunit gamma 2 [Source:HGNC Symbol;Acc:HGNC:4832];hemoglobin subunit gamma 1 [Source:HGNC Symbol;Acc:HGNC:4831];hemoglobin subunit epsilon 1 [Source:HGNC Symbol;Acc:HGNC:4830];olfactory receptor family 51 subfamily B member 5 [Source:HGNC Symbol;Acc:HGNC:19599]",{"v":18.0239765775558,"d":"18.02"},{"v":24.5177253301998,"d":"24.52"},{"v":0.735140651704532,"d":"0.74"},{"v":-0.443907793096647,"d":"-0.44"},{"v":0.523671345234723,"d":"0.52"},1,"down","no"]
["MSTRG.7122","PITPNC1","ENST00000581322;ENST00000580974;ENST00000581923;ENST00000584554;ENST00000578527;ENST00000584471;ENST00000299954","GO:0006810(transport);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0005622(intracellular);GO:0005737(cytoplasm);GO:0005515(protein binding);GO:0007165(signal transduction);GO:0006869(lipid transport);GO:0008289(lipid binding);GO:0008526(phosphatidylinositol transporter activity);GO:0035091(phosphatidylinositol binding);GO:0070300(phosphatidic acid binding);GO:0015914(phospholipid transport);GO:1901611(phosphatidylglycerol binding);GO:1901611(phosphatidylglycerol binding)","NA","NA","NA","phosphatidylinositol transfer protein, cytoplasmic 1 [Source:HGNC Symbol;Acc:HGNC:21045]",{"v":2.63218578987083,"d":"2.63"},{"v":3.579805223558,"d":"3.58"},{"v":0.735287431994604,"d":"0.74"},{"v":-0.443619769221645,"d":"-0.44"},{"v":0.525981494889177,"d":"0.53"},1,"down","no"]
["ENSG00000134668","SPOCD1","ENST00000360482;ENST00000452755;ENST00000257100;ENST00000528579;ENST00000473361;ENST00000485944;ENST00000532604;ENST00000468720","GO:0006351(transcription, DNA-templated);GO:0010923(negative regulation of phosphatase activity);GO:0010923(negative regulation of phosphatase activity)","NA","NA","NA","SPOC domain containing 1 [Source:HGNC Symbol;Acc:HGNC:26338]",{"v":0.643319391813691,"d":"0.64"},{"v":0.879350568101623,"d":"0.88"},{"v":0.731584666173031,"d":"0.73"},{"v":-0.450903258001882,"d":"-0.45"},{"v":0.526379767367213,"d":"0.53"},1,"down","no"]
["ENSG00000141446","ESCO1","ENST00000269214;ENST00000383276;ENST00000622333;ENST00000580101","GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0016740(transferase activity);GO:0016746(transferase activity, transferring acyl groups);GO:0005694(chromosome);GO:0006275(regulation of DNA replication);GO:0008270(zinc ion binding);GO:0000785(chromatin);GO:0007049(cell cycle);GO:0007062(sister chromatid cohesion);GO:0034421(post-translational protein acetylation);GO:0008080(N-acetyltransferase activity);GO:0005654(nucleoplasm);GO:0018394(peptidyl-lysine acetylation);GO:0061733(peptide-lysine-N-acetyltransferase activity);GO:0061733(peptide-lysine-N-acetyltransferase activity)","NA","NA","NA","establishment of sister chromatid cohesion N-acetyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:24645]",{"v":2.62883026909985,"d":"2.63"},{"v":3.57926692265507,"d":"3.58"},{"v":0.734460526668351,"d":"0.73"},{"v":-0.445243139177441,"d":"-0.45"},{"v":0.527245476104971,"d":"0.53"},1,"down","no"]
["MSTRG.3414","PCBP2;AC023509.1;PRR13;uc_338;PCBP2-OT1","ENST00000553064;MSTRG.3414.4;MSTRG.3414.25;MSTRG.3414.26;ENST00000547717;ENST00000379786;ENST00000548933;MSTRG.3414.24;ENST00000547048;ENST00000546581;ENST00000551003;ENST00000550585;ENST00000549581;ENST00000552296;ENST00000549135;ENST00000547368;ENST00000549924;ENST00000552846;ENST00000429243;ENST00000551945;ENST00000549068;ENST00000439930;ENST00000447282;MSTRG.3414.23;ENST00000437231;MSTRG.3414.33;ENST00000612963;ENST00000549740;ENST00000359462;ENST00000550733;ENST00000562264;ENST00000549272;ENST00000552819;MSTRG.3414.21;ENST00000547987;ENST00000359282;ENST00000552980;ENST00000551104;ENST00000550910;ENST00000550192;MSTRG.3414.30;ENST00000546463;ENST00000551365;ENST00000549863;ENST00000546652;ENST00000550520;ENST00000455667;ENST00000634357;ENST00000548190;ENST00000547859","GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0003677(DNA binding);GO:0030529(intracellular ribonucleoprotein complex);GO:0005515(protein binding);GO:0002376(immune system process);GO:0045087(innate immune response);GO:0005925(focal adhesion);GO:0051607(defense response to virus);GO:0070062(extracellular exosome);GO:0031625(ubiquitin protein ligase binding);GO:0019899(enzyme binding);GO:0075522(IRES-dependent viral translational initiation);GO:0043161(proteasome-mediated ubiquitin-dependent protein catabolic process);GO:0032480(negative regulation of type I interferon production);GO:0000398(mRNA splicing, via spliceosome);GO:0016070(RNA metabolic process);GO:0050687(negative regulation of defense response to virus);GO:0016071(mRNA metabolic process);GO:0039694(viral RNA genome replication);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0039694(viral RNA genome replication)","04216(Ferroptosis);04216(Ferroptosis)","K13162","NA","poly(rC) binding protein 2 [Source:HGNC Symbol;Acc:HGNC:8648];proline rich 13 [Source:HGNC Symbol;Acc:HGNC:24528];TUC338 [Source:RFAM;Acc:RF02271];PCBP2 overlapping transcript 1 [Source:HGNC Symbol;Acc:HGNC:49150]",{"v":27.2383406793286,"d":"27.24"},{"v":36.9537528151943,"d":"36.95"},{"v":0.737092679478253,"d":"0.74"},{"v":-0.440082064688712,"d":"-0.44"},{"v":0.528011240670742,"d":"0.53"},1,"down","no"]
["MSTRG.10897","MAP4","ENST00000429422;ENST00000360240;ENST00000383736;ENST00000497735;ENST00000633710;ENST00000423088;ENST00000462206;ENST00000395734;ENST00000477765;ENST00000482752;ENST00000426837;ENST00000420772","GO:0005737(cytoplasm);GO:0005856(cytoskeleton);GO:0015631(tubulin binding);GO:0005874(microtubule);GO:0003723(RNA binding);GO:0005515(protein binding);GO:0070062(extracellular exosome);GO:0008017(microtubule binding);GO:0043005(neuron projection);GO:0005875(microtubule associated complex);GO:0005198(structural molecule activity);GO:0007052(mitotic spindle organization);GO:0031175(neuron projection development);GO:0051012(microtubule sliding);GO:0051294(establishment of spindle orientation);GO:0051301(cell division);GO:1902856(negative regulation of non-motile cilium assembly);GO:0005930(axoneme);GO:0072686(mitotic spindle);GO:0014069(postsynaptic density);GO:0014069(postsynaptic density)","NA","NA","NA","microtubule associated protein 4 [Source:HGNC Symbol;Acc:HGNC:6862]",{"v":2.93059666291909,"d":"2.93"},{"v":2.24594190791675,"d":"2.25"},{"v":1.30484081203926,"d":"1.30"},{"v":0.383873811630429,"d":"0.38"},{"v":0.530886732533941,"d":"0.53"},1,"up","no"]
["ENSG00000188848","BEND4","ENST00000502486","NA","NA","NA","NA","BEN domain containing 4 [Source:HGNC Symbol;Acc:HGNC:23815]",{"v":0.159049,"d":"0.16"},{"v":0.119708,"d":"0.12"},{"v":1.32864136064423,"d":"1.33"},{"v":0.409951731366942,"d":"0.41"},{"v":0.531401815395389,"d":"0.53"},1,"up","no"]
["MSTRG.6105","IST1;ATXN1L","ENST00000329908;ENST00000378799;ENST00000537571;ENST00000427980;ENST00000538565;ENST00000534994;ENST00000538104;ENST00000378798;ENST00000538850;ENST00000536027;ENST00000538709;ENST00000456820;ENST00000544564;ENST00000606369;ENST00000545388;ENST00000541918;ENST00000566536;ENST00000568581;ENST00000541180;ENST00000569119;ENST00000537613;ENST00000545518;ENST00000541571;ENST00000539186;ENST00000565676;ENST00000535424","GO:0015031(protein transport);GO:0043231(intracellular membrane-bounded organelle);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0051301(cell division);GO:0005829(cytosol);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0007049(cell cycle);GO:0031410(cytoplasmic vesicle);GO:0005813(centrosome);GO:0005815(microtubule organizing center);GO:0030496(midbody);GO:0005576(extracellular region);GO:0045296(cadherin binding);GO:0070062(extracellular exosome);GO:0036258(multivesicular body assembly);GO:0043312(neutrophil degranulation);GO:0019904(protein domain specific binding);GO:0032403(protein complex binding);GO:0035578(azurophil granule lumen);GO:0005635(nuclear envelope);GO:0000910(cytokinesis);GO:0005793(endoplasmic reticulum-Golgi intermediate compartment);GO:0045862(positive regulation of proteolysis);GO:0000785(chromatin);GO:0045184(establishment of protein localization);GO:1904903(ESCRT III complex disassembly);GO:0008104(protein localization);GO:0019076(viral release from host cell);GO:0090543(Flemming body);GO:0090541(MIT domain binding);GO:0009838(abscission);GO:0046745(viral capsid secondary envelopment);GO:0048672(positive regulation of collateral sprouting);GO:0003723(RNA binding);GO:0005730(nucleolus);GO:0005654(nucleoplasm);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0042995(cell projection);GO:0030425(dendrite);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0030198(extracellular matrix organization);GO:0048286(lung alveolus development);GO:1902035(positive regulation of hematopoietic stem cell proliferation);GO:0048672(positive regulation of collateral sprouting)","04144(Endocytosis);04144(Endocytosis)","K19476","NA","IST1, ESCRT-III associated factor [Source:HGNC Symbol;Acc:HGNC:28977];ataxin 1 like [Source:HGNC Symbol;Acc:HGNC:33279]",{"v":7.33940094076137,"d":"7.34"},{"v":9.9266826005571,"d":"9.93"},{"v":0.739360895889778,"d":"0.74"},{"v":-0.435649352143577,"d":"-0.44"},{"v":0.533025123543439,"d":"0.53"},1,"down","no"]
["ENSG00000082269","FAM135A","ENST00000505675;ENST00000361499;ENST00000194672;ENST00000425415;ENST00000393299;ENST00000418814;ENST00000505769;ENST00000507085;ENST00000457062","GO:0052689(carboxylic ester hydrolase activity);GO:0044255(cellular lipid metabolic process);GO:0044255(cellular lipid metabolic process)","NA","NA","NA","family with sequence similarity 135 member A [Source:HGNC Symbol;Acc:HGNC:21084]",{"v":0.282520635754084,"d":"0.28"},{"v":0.385580325809803,"d":"0.39"},{"v":0.732715382095103,"d":"0.73"},{"v":-0.44867519199917,"d":"-0.45"},{"v":0.533591246166043,"d":"0.53"},1,"down","no"]
["ENSG00000235532","LINC00402","ENST00000419499","NA","NA","NA","NA","long intergenic non-protein coding RNA 402 [Source:HGNC Symbol;Acc:HGNC:42732]",{"v":0.815969,"d":"0.82"},{"v":0.618199,"d":"0.62"},{"v":1.31991316711933,"d":"1.32"},{"v":0.400443022396674,"d":"0.40"},{"v":0.535083413642676,"d":"0.54"},1,"up","no"]
["ENSG00000181894","ZNF329","ENST00000597186;ENST00000601887;ENST00000500161;ENST00000598312","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0005515(protein binding)","NA","NA","NA","zinc finger protein 329 [Source:HGNC Symbol;Acc:HGNC:14209]",{"v":1.76433834068229,"d":"1.76"},{"v":1.34776356115108,"d":"1.35"},{"v":1.30908594915226,"d":"1.31"},{"v":0.388559821763698,"d":"0.39"},{"v":0.536795813763111,"d":"0.54"},1,"up","no"]
["MSTRG.2325","COMMD9","ENST00000263401;ENST00000533308;ENST00000355500;ENST00000526789;ENST00000452374;ENST00000528608;ENST00000533643;ENST00000532705","GO:0006810(transport);GO:0005634(nucleus);GO:0005794(Golgi apparatus);GO:0005829(cytosol);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0006811(ion transport);GO:0005515(protein binding);GO:0006814(sodium ion transport);GO:0031410(cytoplasmic vesicle);GO:0005576(extracellular region);GO:0043312(neutrophil degranulation);GO:0034774(secretory granule lumen);GO:1904813(ficolin-1-rich granule lumen);GO:0042632(cholesterol homeostasis);GO:0042632(cholesterol homeostasis)","NA","NA","NA","COMM domain containing 9 [Source:HGNC Symbol;Acc:HGNC:25014]",{"v":2.07669898103762,"d":"2.08"},{"v":2.80417582645631,"d":"2.80"},{"v":0.740573740578166,"d":"0.74"},{"v":-0.433284699859731,"d":"-0.43"},{"v":0.53697272097873,"d":"0.54"},1,"down","no"]
["ENSG00000100376","FAM118A","ENST00000441876;ENST00000479180;ENST00000459849;ENST00000462361;ENST00000476754;ENST00000483102;ENST00000405673;ENST00000216214;ENST00000477714;ENST00000427777;ENST00000487732;ENST00000452238","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005515(protein binding);GO:0042802(identical protein binding);GO:0042802(identical protein binding)","NA","NA","NA","family with sequence similarity 118 member A [Source:HGNC Symbol;Acc:HGNC:1313]",{"v":0.683143970823096,"d":"0.68"},{"v":0.521763147727273,"d":"0.52"},{"v":1.30929900626132,"d":"1.31"},{"v":0.388794604991206,"d":"0.39"},{"v":0.539179453553477,"d":"0.54"},1,"up","no"]
["MSTRG.13335","PPIL4","ENST00000253329;ENST00000340881","GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0005634(nucleus);GO:0016853(isomerase activity);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0003755(peptidyl-prolyl cis-trans isomerase activity);GO:0000413(protein peptidyl-prolyl isomerization);GO:0006457(protein folding);GO:1901407(regulation of phosphorylation of RNA polymerase II C-terminal domain);GO:1901407(regulation of phosphorylation of RNA polymerase II C-terminal domain)","NA","NA","NA","peptidylprolyl isomerase like 4 [Source:HGNC Symbol;Acc:HGNC:15702]",{"v":3.42154593877551,"d":"3.42"},{"v":4.61038043197279,"d":"4.61"},{"v":0.742139610659293,"d":"0.74"},{"v":-0.43023748397179,"d":"-0.43"},{"v":0.539520937678852,"d":"0.54"},1,"down","no"]
["MSTRG.6394","EIF5A","ENST00000336452;ENST00000419711;ENST00000355068;ENST00000336458;ENST00000572815;ENST00000575001;ENST00000573542;ENST00000573714;MSTRG.6394.2;ENST00000416016","GO:0003723(RNA binding);GO:0006810(transport);GO:0051028(mRNA transport);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0015031(protein transport);GO:0006412(translation);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005515(protein binding);GO:0006915(apoptotic process);GO:0003746(translation elongation factor activity);GO:0006414(translational elongation);GO:0006406(mRNA export from nucleus);GO:0005643(nuclear pore);GO:0043022(ribosome binding);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0006452(translational frameshifting);GO:0045901(positive regulation of translational elongation);GO:0045905(positive regulation of translational termination);GO:0008284(positive regulation of cell proliferation);GO:0047485(protein N-terminus binding);GO:0005642(annulate lamellae);GO:0006913(nucleocytoplasmic transport);GO:0017070(U6 snRNA binding);GO:0006611(protein export from nucleus);GO:0008612(peptidyl-lysine modification to peptidyl-hypusine);GO:0007204(positive regulation of cytosolic calcium ion concentration);GO:0007568(aging);GO:0010666(positive regulation of cardiac muscle cell apoptotic process);GO:0043065(positive regulation of apoptotic process);GO:0043066(negative regulation of apoptotic process);GO:0051149(positive regulation of muscle cell differentiation);GO:0097067(cellular response to thyroid hormone stimulus);GO:2000379(positive regulation of reactive oxygen species metabolic process);GO:0030425(dendrite);GO:0043025(neuronal cell body);GO:0043025(neuronal cell body)","NA","NA","NA","eukaryotic translation initiation factor 5A [Source:HGNC Symbol;Acc:HGNC:3300]",{"v":48.1158044063943,"d":"48.12"},{"v":37.1201833754885,"d":"37.12"},{"v":1.29621677564682,"d":"1.30"},{"v":0.374307010659433,"d":"0.37"},{"v":0.540445469849094,"d":"0.54"},1,"up","no"]
["MSTRG.14802","SMC5","ENST00000361138;ENST00000475540;ENST00000618375;ENST00000471372","GO:0005634(nucleus);GO:0016607(nuclear speck);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0051301(cell division);GO:0005694(chromosome);GO:0030054(cell junction);GO:0006281(DNA repair);GO:0005515(protein binding);GO:0006310(DNA recombination);GO:0006974(cellular response to DNA damage stimulus);GO:0007049(cell cycle);GO:0000724(double-strand break repair via homologous recombination);GO:0030915(Smc5-Smc6 complex);GO:0007062(sister chromatid cohesion);GO:0000781(chromosome, telomeric region);GO:0005654(nucleoplasm);GO:0016605(PML body);GO:0090398(cellular senescence);GO:0035861(site of double-strand break);GO:0051984(positive regulation of chromosome segregation);GO:0034184(positive regulation of maintenance of mitotic sister chromatid cohesion);GO:0000722(telomere maintenance via recombination);GO:0000803(sex chromosome);GO:0035061(interchromatin granule);GO:0035061(interchromatin granule)","NA","NA","NA","structural maintenance of chromosomes 5 [Source:HGNC Symbol;Acc:HGNC:20465]",{"v":4.15444308814223,"d":"4.15"},{"v":3.20526240229019,"d":"3.21"},{"v":1.2961319750838,"d":"1.30"},{"v":0.374212624167848,"d":"0.37"},{"v":0.542050277336375,"d":"0.54"},1,"up","no"]
["MSTRG.3949","UFM1","ENST00000239878;ENST00000379649;ENST00000494372;ENST00000437952","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005515(protein binding);GO:0005783(endoplasmic reticulum);GO:0070062(extracellular exosome);GO:0033146(regulation of intracellular estrogen receptor signaling pathway);GO:0034976(response to endoplasmic reticulum stress);GO:0071569(protein ufmylation);GO:1990592(protein K69-linked ufmylation);GO:0043066(negative regulation of apoptotic process);GO:0043066(negative regulation of apoptotic process)","NA","NA","NA","ubiquitin fold modifier 1 [Source:HGNC Symbol;Acc:HGNC:20597]",{"v":2.65623069625742,"d":"2.66"},{"v":3.57351572683706,"d":"3.57"},{"v":0.74331020185784,"d":"0.74"},{"v":-0.427963685890688,"d":"-0.43"},{"v":0.542311674708339,"d":"0.54"},1,"down","no"]
["MSTRG.5914","BRD7","ENST00000394689;ENST00000562383;ENST00000394688;ENST00000569774;ENST00000567826;ENST00000401491","GO:0005634(nucleus);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0005515(protein binding);GO:0007049(cell cycle);GO:0016055(Wnt signaling pathway);GO:0003713(transcription coactivator activity);GO:0045893(positive regulation of transcription, DNA-templated);GO:0003714(transcription corepressor activity);GO:0008285(negative regulation of cell proliferation);GO:0005737(cytoplasm);GO:0044212(transcription regulatory region DNA binding);GO:0045892(negative regulation of transcription, DNA-templated);GO:1901796(regulation of signal transduction by p53 class mediator);GO:0002039(p53 binding);GO:0070577(lysine-acetylated histone binding);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:2000134(negative regulation of G1/S transition of mitotic cell cycle);GO:0008134(transcription factor binding);GO:0035066(positive regulation of histone acetylation);GO:0042393(histone binding);GO:0090544(BAF-type complex);GO:0090544(BAF-type complex)","05225(Hepatocellular carcinoma);05225(Hepatocellular carcinoma)","K11723","NA","bromodomain containing 7 [Source:HGNC Symbol;Acc:HGNC:14310]",{"v":5.29767575588789,"d":"5.30"},{"v":4.09165907324541,"d":"4.09"},{"v":1.29475004174429,"d":"1.29"},{"v":0.372673604982974,"d":"0.37"},{"v":0.543348983528576,"d":"0.54"},1,"up","no"]
["MSTRG.6886","SLC4A1","ENST00000497360;ENST00000262418;ENST00000498270;ENST00000399246;ENST00000471005","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005215(transporter activity);GO:0006811(ion transport);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0035725(sodium ion transmembrane transport);GO:0006821(chloride transport);GO:1902476(chloride transmembrane transport);GO:0008509(anion transmembrane transporter activity);GO:0006820(anion transport);GO:0098656(anion transmembrane transport);GO:0005452(inorganic anion exchanger activity);GO:0005887(integral component of plasma membrane);GO:0070062(extracellular exosome);GO:0072562(blood microparticle);GO:0016323(basolateral plasma membrane);GO:0042803(protein homodimerization activity);GO:0030018(Z disc);GO:0051453(regulation of intracellular pH);GO:0030506(ankyrin binding);GO:0015701(bicarbonate transport);GO:0008510(sodium:bicarbonate symporter activity);GO:0015106(bicarbonate transmembrane transporter activity);GO:0015108(chloride transmembrane transporter activity);GO:0015301(anion:anion antiporter activity);GO:0043495(protein anchor);GO:0006873(cellular ion homeostasis);GO:0030863(cortical cytoskeleton);GO:0015698(inorganic anion transport);GO:0015698(inorganic anion transport)","04966(Collecting duct acid secretion);04966(Collecting duct acid secretion)","K06573","NA","solute carrier family 4 member 1 (Diego blood group) [Source:HGNC Symbol;Acc:HGNC:11027]",{"v":73.9209259655759,"d":"73.92"},{"v":57.1515465818044,"d":"57.15"},{"v":1.29341952032336,"d":"1.29"},{"v":0.371190288856402,"d":"0.37"},{"v":0.543560534203631,"d":"0.54"},1,"up","no"]
["MSTRG.1517","WDR37","ENST00000263150;ENST00000620998;ENST00000358220;ENST00000381329;ENST00000436154;ENST00000482165","GO:0030687(preribosome, large subunit precursor);GO:0000470(maturation of LSU-rRNA);GO:0000460(maturation of 5.8S rRNA);GO:0070545(PeBoW complex);GO:0070545(PeBoW complex)","NA","NA","NA","WD repeat domain 37 [Source:HGNC Symbol;Acc:HGNC:31406]",{"v":2.344843270686,"d":"2.34"},{"v":1.81157535608204,"d":"1.81"},{"v":1.2943669512911,"d":"1.29"},{"v":0.372246677422307,"d":"0.37"},{"v":0.545104223165353,"d":"0.55"},1,"up","no"]
["MSTRG.1174","RCSD1","ENST00000367854;ENST00000537350;ENST00000461790;ENST00000361496;ENST00000472038;ENST00000475127","GO:0003009(skeletal muscle contraction);GO:0005884(actin filament);GO:0071474(cellular hyperosmotic response);GO:0051015(actin filament binding);GO:0051015(actin filament binding)","NA","NA","NA","RCSD domain containing 1 [Source:HGNC Symbol;Acc:HGNC:28310]",{"v":12.5752984616999,"d":"12.58"},{"v":16.8542097813921,"d":"16.85"},{"v":0.746122103902116,"d":"0.75"},{"v":-0.422516346070436,"d":"-0.42"},{"v":0.54540926382859,"d":"0.55"},1,"down","no"]
["ENSG00000181284","TMEM102","ENST00000323206;ENST00000396568","GO:0005739(mitochondrion);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0042981(regulation of apoptotic process);GO:0005886(plasma membrane);GO:0007165(signal transduction);GO:0006915(apoptotic process);GO:0005515(protein binding);GO:0005622(intracellular);GO:0043234(protein complex);GO:0009986(cell surface);GO:2000406(positive regulation of T cell migration);GO:0034097(response to cytokine);GO:0045785(positive regulation of cell adhesion);GO:0010820(positive regulation of T cell chemotaxis);GO:0050730(regulation of peptidyl-tyrosine phosphorylation);GO:1901028(regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway);GO:1901028(regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway)","NA","NA","NA","transmembrane protein 102 [Source:HGNC Symbol;Acc:HGNC:26722]",{"v":4.1167849544387,"d":"4.12"},{"v":3.18005892437764,"d":"3.18"},{"v":1.29456247583349,"d":"1.29"},{"v":0.372464591657633,"d":"0.37"},{"v":0.547081099344651,"d":"0.55"},1,"up","no"]
["ENSG00000143771","CNIH4","ENST00000465271;ENST00000468318;ENST00000469200;ENST00000366856;ENST00000477413;ENST00000366860;ENST00000366857","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0006810(transport);GO:0015031(protein transport);GO:0005783(endoplasmic reticulum);GO:0016192(vesicle-mediated transport);GO:0005515(protein binding);GO:0006888(ER to Golgi vesicle-mediated transport);GO:0005793(endoplasmic reticulum-Golgi intermediate compartment);GO:0031730(CCR5 chemokine receptor binding);GO:0031730(CCR5 chemokine receptor binding)","NA","NA","NA","cornichon family AMPA receptor auxiliary protein 4 [Source:HGNC Symbol;Acc:HGNC:25013]",{"v":2.40790404178109,"d":"2.41"},{"v":1.86146666104355,"d":"1.86"},{"v":1.29355206417245,"d":"1.29"},{"v":0.371338122218851,"d":"0.37"},{"v":0.548010646860511,"d":"0.55"},1,"up","no"]
["ENSG00000125843","AP5S1","ENST00000615891;ENST00000379567;ENST00000379573;ENST00000246041;ENST00000455742","GO:0000724(double-strand break repair via homologous recombination);GO:0016197(endosomal transport);GO:0030119(AP-type membrane coat adaptor complex);GO:0006810(transport);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0015031(protein transport);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0005765(lysosomal membrane);GO:0005886(plasma membrane);GO:0006281(DNA repair);GO:0006974(cellular response to DNA damage stimulus);GO:0005764(lysosome);GO:0005515(protein binding);GO:0005768(endosome);GO:0031902(late endosome membrane);GO:0005770(late endosome);GO:0005770(late endosome)","NA","NA","NA","adaptor related protein complex 5 sigma 1 subunit [Source:HGNC Symbol;Acc:HGNC:15875]",{"v":1.0176299701275,"d":"1.02"},{"v":0.784452358105647,"d":"0.78"},{"v":1.29724891462491,"d":"1.30"},{"v":0.375455328811009,"d":"0.38"},{"v":0.548840043901317,"d":"0.55"},1,"up","no"]
["MSTRG.590","TCEANC2","ENST00000234827;ENST00000371331;ENST00000498272","GO:0005634(nucleus);GO:0006351(transcription, DNA-templated);GO:0005515(protein binding);GO:0005515(protein binding)","NA","NA","NA","transcription elongation factor A N-terminal and central domain containing 2 [Source:HGNC Symbol;Acc:HGNC:26494]",{"v":0.969502330441899,"d":"0.97"},{"v":0.751520648608838,"d":"0.75"},{"v":1.29005414852749,"d":"1.29"},{"v":0.367431622371444,"d":"0.37"},{"v":0.550284711233141,"d":"0.55"},1,"up","no"]
["MSTRG.8869","CAPG","ENST00000409724;ENST00000263867;ENST00000491267;ENST00000453973;ENST00000449030;ENST00000415012;ENST00000439385;ENST00000447219;ENST00000409275;ENST00000483659;ENST00000471064;ENST00000459793;ENST00000409670;ENST00000409921","GO:0005737(cytoplasm);GO:0005634(nucleus);GO:0051015(actin filament binding);GO:0003779(actin binding);GO:0051016(barbed-end actin filament capping);GO:0051693(actin filament capping);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0042470(melanosome);GO:0005654(nucleoplasm);GO:0005730(nucleolus);GO:0045296(cadherin binding);GO:0070062(extracellular exosome);GO:0005814(centriole);GO:0019904(protein domain specific binding);GO:0006461(protein complex assembly);GO:0032403(protein complex binding);GO:0072686(mitotic spindle);GO:0090543(Flemming body);GO:0008290(F-actin capping protein complex);GO:0008290(F-actin capping protein complex)","NA","NA","NA","capping actin protein, gelsolin like [Source:HGNC Symbol;Acc:HGNC:1474]",{"v":19.5163272079018,"d":"19.52"},{"v":26.090275844649,"d":"26.09"},{"v":0.748030696344842,"d":"0.75"},{"v":-0.418830620822832,"d":"-0.42"},{"v":0.550434179898291,"d":"0.55"},1,"down","no"]
["ENSG00000165392","WRN","ENST00000298139;ENST00000520169","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0016607(nuclear speck);GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0016787(hydrolase activity);GO:0004386(helicase activity);GO:0008026(ATP-dependent helicase activity);GO:0006139(nucleobase-containing compound metabolic process);GO:0003824(catalytic activity);GO:0003677(DNA binding);GO:0005622(intracellular);GO:0042803(protein homodimerization activity);GO:0006281(DNA repair);GO:0090305(nucleic acid phosphodiester bond hydrolysis);GO:0005515(protein binding);GO:0008152(metabolic process);GO:0006974(cellular response to DNA damage stimulus);GO:0004527(exonuclease activity);GO:0000287(magnesium ion binding);GO:0004518(nuclease activity);GO:0008408(3'-5' exonuclease activity);GO:0006260(DNA replication);GO:0006310(DNA recombination);GO:0005654(nucleoplasm);GO:0005730(nucleolus);GO:0044237(cellular metabolic process);GO:0005813(centrosome);GO:0005737(cytoplasm);GO:0016887(ATPase activity);GO:0031297(replication fork processing);GO:0004003(ATP-dependent DNA helicase activity);GO:0000723(telomere maintenance);GO:0006284(base-excision repair);GO:0006979(response to oxidative stress);GO:0000403(Y-form DNA binding);GO:1901796(regulation of signal transduction by p53 class mediator);GO:0042981(regulation of apoptotic process);GO:0032403(protein complex binding);GO:0000781(chromosome, telomeric region);GO:0007569(cell aging);GO:0000731(DNA synthesis involved in DNA repair);GO:0000732(strand displacement);GO:0090656(t-circle formation);GO:0000724(double-strand break repair via homologous recombination);GO:0006302(double-strand break repair);GO:0032508(DNA duplex unwinding);GO:0003678(DNA helicase activity);GO:0043140(ATP-dependent 3'-5' DNA helicase activity);GO:0006259(DNA metabolic process);GO:0030145(manganese ion binding);GO:0007568(aging);GO:0071480(cellular response to gamma radiation);GO:0043138(3'-5' DNA helicase activity);GO:0010225(response to UV-C);GO:0044806(G-quadruplex DNA unwinding);GO:0000405(bubble DNA binding);GO:0051880(G-quadruplex DNA binding);GO:0000400(four-way junction DNA binding);GO:0009378(four-way junction helicase activity);GO:0061749(forked DNA-dependent helicase activity);GO:0061821(telomeric D-loop binding);GO:0061849(telomeric G-quadruplex DNA binding);GO:1905773(8-hydroxy-2'-deoxyguanosine DNA binding);GO:0061820(telomeric D-loop disassembly);GO:0005657(replication fork);GO:0032389(MutLalpha complex);GO:0003682(chromatin binding);GO:0070337(3'-flap-structured DNA binding);GO:0001302(replicative cell aging);GO:0007420(brain development);GO:0009267(cellular response to starvation);GO:0010259(multicellular organism aging);GO:0032066(nucleolus to nucleoplasm transport);GO:0040009(regulation of growth rate);GO:0051345(positive regulation of hydrolase activity);GO:0098530(positive regulation of strand invasion);GO:0043005(neuron projection);GO:0043005(neuron projection)","NA","NA","NA","Werner syndrome RecQ like helicase [Source:HGNC Symbol;Acc:HGNC:12791]",{"v":0.700274433262336,"d":"0.70"},{"v":0.541402898473553,"d":"0.54"},{"v":1.29344418959837,"d":"1.29"},{"v":0.37121780498768,"d":"0.37"},{"v":0.552413235644014,"d":"0.55"},1,"up","no"]
["MSTRG.5761","LCMT1","ENST00000399069;ENST00000576382;ENST00000572869;ENST00000570981;ENST00000572761;ENST00000380962;ENST00000575396;ENST00000380966;ENST00000577157;ENST00000576625;ENST00000574450","GO:0008168(methyltransferase activity);GO:0016740(transferase activity);GO:0032259(methylation);GO:0005515(protein binding);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0000086(G2/M transition of mitotic cell cycle);GO:0042981(regulation of apoptotic process);GO:0006464(cellular protein modification process);GO:0003880(protein C-terminal carboxyl O-methyltransferase activity);GO:0006479(protein methylation);GO:0008276(protein methyltransferase activity);GO:0008757(S-adenosylmethionine-dependent methyltransferase activity);GO:0018423(protein C-terminal leucine carboxyl O-methyltransferase activity);GO:0006481(C-terminal protein methylation);GO:0010906(regulation of glucose metabolic process);GO:0031333(negative regulation of protein complex assembly);GO:0090266(regulation of mitotic cell cycle spindle assembly checkpoint);GO:0090266(regulation of mitotic cell cycle spindle assembly checkpoint)","NA","NA","NA","leucine carboxyl methyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:17557]",{"v":3.37231351573292,"d":"3.37"},{"v":2.62219695932464,"d":"2.62"},{"v":1.28606415461693,"d":"1.29"},{"v":0.3629626125252,"d":"0.36"},{"v":0.552776062405165,"d":"0.55"},1,"up","no"]
["MSTRG.13739","YWHAG","ENST00000307630","GO:0005739(mitochondrion);GO:0003723(RNA binding);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0019904(protein domain specific binding);GO:0005515(protein binding);GO:0071901(negative regulation of protein serine/threonine kinase activity);GO:0005925(focal adhesion);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0061024(membrane organization);GO:0000086(G2/M transition of mitotic cell cycle);GO:0010389(regulation of G2/M transition of mitotic cell cycle);GO:0097711(ciliary basal body docking);GO:0005159(insulin-like growth factor receptor binding);GO:0009966(regulation of signal transduction);GO:0048167(regulation of synaptic plasticity);GO:0006469(negative regulation of protein kinase activity);GO:1900740(positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway);GO:0030659(cytoplasmic vesicle membrane);GO:0005080(protein kinase C binding);GO:0008426(protein kinase C inhibitor activity);GO:0030971(receptor tyrosine kinase binding);GO:0006605(protein targeting);GO:0032869(cellular response to insulin stimulus);GO:0045664(regulation of neuron differentiation);GO:0031982(vesicle);GO:0043209(myelin sheath)","04390(Hippo signaling pathway);04151(PI3K-Akt signaling pathway);04110(Cell cycle);04114(Oocyte meiosis);05203(Viral carcinogenesis);05169(Epstein-Barr virus infection)","K16198","NA","tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein gamma [Source:HGNC Symbol;Acc:HGNC:12852]",{"v":8.784356,"d":"8.78"},{"v":11.705643,"d":"11.71"},{"v":0.750437716236519,"d":"0.75"},{"v":-0.414195756826193,"d":"-0.41"},{"v":0.554618106907841,"d":"0.55"},1,"down","no"]
["MSTRG.2708","AP001324.1","ENST00000428553","NA","NA","NA","NA",null,{"v":20.263451,"d":"20.26"},{"v":15.778142,"d":"15.78"},{"v":1.28427358557174,"d":"1.28"},{"v":0.360952568896029,"d":"0.36"},{"v":0.556650100435092,"d":"0.56"},1,"up","no"]
["ENSG00000162836","ACP6","ENST00000583509;ENST00000487562;ENST00000614551;ENST00000609196;ENST00000613673;ENST00000460583;ENST00000611629","GO:0016311(dephosphorylation);GO:0003993(acid phosphatase activity);GO:0002244(hematopoietic progenitor cell differentiation);GO:0005739(mitochondrion);GO:0016787(hydrolase activity);GO:0006629(lipid metabolic process);GO:0005759(mitochondrial matrix);GO:0005737(cytoplasm);GO:0006654(phosphatidic acid biosynthetic process);GO:0006644(phospholipid metabolic process);GO:0052642(lysophosphatidic acid phosphatase activity);GO:2001311(lysobisphosphatidic acid metabolic process);GO:2001311(lysobisphosphatidic acid metabolic process)","NA","NA","NA","acid phosphatase 6, lysophosphatidic [Source:HGNC Symbol;Acc:HGNC:29609]",{"v":0.162813623494983,"d":"0.16"},{"v":0.219061712458194,"d":"0.22"},{"v":0.743231766372933,"d":"0.74"},{"v":-0.428115929806606,"d":"-0.43"},{"v":0.557092778029422,"d":"0.56"},1,"down","no"]
["ENSG00000136682","CBWD2","ENST00000259199;ENST00000479583;ENST00000358604;ENST00000468417;ENST00000433343;ENST00000456188;ENST00000492566;ENST00000463627;ENST00000490323;ENST00000416503;ENST00000490446","GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0005524(ATP binding)","NA","NA","NA","COBW domain containing 2 [Source:HGNC Symbol;Acc:HGNC:17907]",{"v":0.891544535731301,"d":"0.89"},{"v":1.19347525238209,"d":"1.19"},{"v":0.747015519552536,"d":"0.75"},{"v":-0.420789878982758,"d":"-0.42"},{"v":0.558124835103186,"d":"0.56"},1,"down","no"]
["ENSG00000153914","SREK1","ENST00000524111;ENST00000522912;ENST00000519259;ENST00000334121;ENST00000284041;ENST00000518110;ENST00000520580;ENST00000522214;ENST00000612404;ENST00000523655;ENST00000519205;ENST00000520058","GO:0016607(nuclear speck);GO:0005654(nucleoplasm);GO:0000381(regulation of alternative mRNA splicing, via spliceosome);GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0006397(mRNA processing);GO:0008380(RNA splicing);GO:0005634(nucleus);GO:0005515(protein binding);GO:0005681(spliceosomal complex);GO:0005681(spliceosomal complex)","NA","NA","NA","splicing regulatory glutamic acid and lysine rich protein 1 [Source:HGNC Symbol;Acc:HGNC:17882]",{"v":1.56777614013158,"d":"1.57"},{"v":1.22214013163377,"d":"1.22"},{"v":1.28281209294368,"d":"1.28"},{"v":0.359309859100837,"d":"0.36"},{"v":0.558864621211026,"d":"0.56"},1,"up","no"]
["MSTRG.292","SLC9A1","ENST00000263980;ENST00000374084;ENST00000374086;ENST00000447808;ENST00000374089","GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0010613(positive regulation of cardiac muscle hypertrophy);GO:0006810(transport);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0055085(transmembrane transport);GO:0005654(nucleoplasm);GO:0005886(plasma membrane);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0006811(ion transport);GO:0015297(antiporter activity);GO:0015299(solute:proton antiporter activity);GO:0015385(sodium:proton antiporter activity);GO:0006812(cation transport);GO:0006814(sodium ion transport);GO:0006885(regulation of pH);GO:0005925(focal adhesion);GO:0005516(calmodulin binding);GO:0005515(protein binding);GO:0070062(extracellular exosome);GO:0048306(calcium-dependent protein binding);GO:0032947(protein complex scaffold);GO:0030027(lamellipodium);GO:0086036(regulation of cardiac muscle cell membrane potential);GO:0051259(protein oligomerization);GO:0030674(protein binding, bridging);GO:0035994(response to muscle stretch);GO:0016477(cell migration);GO:0005887(integral component of plasma membrane);GO:0045121(membrane raft);GO:0030214(hyaluronan catabolic process);GO:0051453(regulation of intracellular pH);GO:0006883(cellular sodium ion homeostasis);GO:0010882(regulation of cardiac muscle contraction by calcium ion signaling);GO:1903281(positive regulation of calcium:sodium antiporter activity);GO:0071872(cellular response to epinephrine stimulus);GO:0005546(phosphatidylinositol-4,5-bisphosphate binding);GO:0015386(potassium:proton antiporter activity);GO:0030346(protein phosphatase 2B binding);GO:0086040(sodium:proton antiporter activity involved in regulation of cardiac muscle cell membrane potential);GO:0002026(regulation of the force of heart contraction);GO:0010447(response to acidic pH);GO:0014070(response to organic cyclic compound);GO:0016049(cell growth);GO:0030011(maintenance of cell polarity);GO:0030154(cell differentiation);GO:0030307(positive regulation of cell growth);GO:0032869(cellular response to insulin stimulus);GO:0035794(positive regulation of mitochondrial membrane permeability);GO:0042493(response to drug);GO:0043065(positive regulation of apoptotic process);GO:0043066(negative regulation of apoptotic process);GO:0045760(positive regulation of action potential);GO:0051492(regulation of stress fiber assembly);GO:0051893(regulation of focal adhesion assembly);GO:0051930(regulation of sensory perception of pain);GO:0055007(cardiac muscle cell differentiation);GO:0070886(positive regulation of calcineurin-NFAT signaling cascade);GO:0070997(neuron death);GO:0071236(cellular response to antibiotic);GO:0071257(cellular response to electrical stimulus);GO:0071260(cellular response to mechanical stimulus);GO:0071407(cellular response to organic cyclic compound);GO:0071436(sodium ion export);GO:0071456(cellular response to hypoxia);GO:0071468(cellular response to acidic pH);GO:0071805(potassium ion transmembrane transport);GO:0086003(cardiac muscle cell contraction);GO:0086092(regulation of the force of heart contraction by cardiac conduction);GO:0098719(sodium ion import across plasma membrane);GO:0098735(positive regulation of the force of heart contraction);GO:1902533(positive regulation of intracellular signal transduction);GO:1902600(hydrogen ion transmembrane transport);GO:0005739(mitochondrion);GO:0009986(cell surface);GO:0014704(intercalated disc);GO:0016323(basolateral plasma membrane);GO:0016324(apical plasma membrane);GO:0030315(T-tubule);GO:0042383(sarcolemma);GO:0048471(perinuclear region of cytoplasm);GO:0090533(cation-transporting ATPase complex);GO:0035725(sodium ion transmembrane transport);GO:0035725(sodium ion transmembrane transport)","04371(Apelin signaling pathway);04024(cAMP signaling pathway);04810(Regulation of actin cytoskeleton);04919(Thyroid hormone signaling pathway);04260(Cardiac muscle contraction);04261(Adrenergic signaling in cardiomyocytes);04970(Salivary secretion);04971(Gastric acid secretion);04972(Pancreatic secretion);04976(Bile secretion);05205(Proteoglycans in cancer);05205(Proteoglycans in cancer)","K05742","NA","solute carrier family 9 member A1 [Source:HGNC Symbol;Acc:HGNC:11071]",{"v":4.19430520555742,"d":"4.19"},{"v":5.57139485319719,"d":"5.57"},{"v":0.752828567365044,"d":"0.75"},{"v":-0.409606720256217,"d":"-0.41"},{"v":0.559903978267245,"d":"0.56"},1,"down","no"]
["MSTRG.11825","SEC24D","ENST00000280551;ENST00000514561;ENST00000509818;ENST00000505134;ENST00000502830;ENST00000514418;ENST00000506622;ENST00000505280;ENST00000511481;ENST00000503683;ENST00000511715","GO:0006810(transport);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0006886(intracellular protein transport);GO:0015031(protein transport);GO:0008270(zinc ion binding);GO:0005794(Golgi apparatus);GO:0006888(ER to Golgi vesicle-mediated transport);GO:0030127(COPII vesicle coat);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005515(protein binding);GO:0000139(Golgi membrane);GO:0048471(perinuclear region of cytoplasm);GO:0016192(vesicle-mediated transport);GO:0003674(molecular_function);GO:0005829(cytosol);GO:0000149(SNARE binding);GO:0019886(antigen processing and presentation of exogenous peptide antigen via MHC class II);GO:0048208(COPII vesicle coating);GO:0012507(ER to Golgi transport vesicle membrane);GO:0002474(antigen processing and presentation of peptide antigen via MHC class I);GO:0001701(in utero embryonic development);GO:0090110(cargo loading into COPII-coated vesicle);GO:0090110(cargo loading into COPII-coated vesicle)","04141(Protein processing in endoplasmic reticulum);04141(Protein processing in endoplasmic reticulum)","K14007","NA","SEC24 homolog D, COPII coat complex component [Source:HGNC Symbol;Acc:HGNC:10706]",{"v":2.74051360665323,"d":"2.74"},{"v":3.63620693639113,"d":"3.64"},{"v":0.753673719508698,"d":"0.75"},{"v":-0.407988007898481,"d":"-0.41"},{"v":0.561122165488838,"d":"0.56"},1,"down","no"]
["MSTRG.1066","MSTO2P","ENST00000314835","NA","NA","NA","NA","misato family member 2, pseudogene [Source:HGNC Symbol;Acc:HGNC:26329]",{"v":2.699284,"d":"2.70"},{"v":2.101223,"d":"2.10"},{"v":1.28462519209051,"d":"1.28"},{"v":0.361347493747533,"d":"0.36"},{"v":0.562272475796598,"d":"0.56"},1,"up","no"]
["ENSG00000127191","TRAF2","ENST00000247668;ENST00000466107;ENST00000429509;ENST00000474950;ENST00000414589;ENST00000469701","GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0005829(cytosol);GO:0007250(activation of NF-kappaB-inducing kinase activity);GO:0042981(regulation of apoptotic process);GO:0004842(ubiquitin-protein transferase activity);GO:0046328(regulation of JNK cascade);GO:0033209(tumor necrosis factor-mediated signaling pathway);GO:0051865(protein autoubiquitination);GO:0051091(positive regulation of sequence-specific DNA binding transcription factor activity);GO:0005737(cytoplasm);GO:0016740(transferase activity);GO:0016567(protein ubiquitination);GO:0007165(signal transduction);GO:0005515(protein binding);GO:0006915(apoptotic process);GO:0005102(receptor binding);GO:0005174(CD40 receptor binding);GO:0019901(protein kinase binding);GO:0031435(mitogen-activated protein kinase kinase kinase binding);GO:0032403(protein complex binding);GO:0006461(protein complex assembly);GO:0030163(protein catabolic process);GO:0034351(negative regulation of glial cell apoptotic process);GO:0043123(positive regulation of I-kappaB kinase/NF-kappaB signaling);GO:0043623(cellular protein complex assembly);GO:0051023(regulation of immunoglobulin secretion);GO:0051092(positive regulation of NF-kappaB transcription factor activity);GO:0051291(protein heterooligomerization);GO:0071732(cellular response to nitric oxide);GO:0097300(programmed necrotic cell death);GO:1903265(positive regulation of tumor necrosis factor-mediated signaling pathway);GO:1903721(positive regulation of I-kappaB phosphorylation);GO:0005938(cell cortex);GO:0009898(cytoplasmic side of plasma membrane);GO:0012506(vesicle membrane);GO:0035631(CD40 receptor complex);GO:0043234(protein complex);GO:0045121(membrane raft);GO:1990597(AIP1-IRE1 complex);GO:1990604(IRE1-TRAF2-ASK1 complex);GO:0042802(identical protein binding);GO:0008289(lipid binding);GO:0005654(nucleoplasm);GO:0016579(protein deubiquitination);GO:0050870(positive regulation of T cell activation);GO:0031625(ubiquitin protein ligase binding);GO:0004871(signal transducer activity);GO:0019903(protein phosphatase binding);GO:0007249(I-kappaB kinase/NF-kappaB signaling);GO:0006919(activation of cysteine-type endopeptidase activity involved in apoptotic process);GO:0097296(activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway);GO:1902041(regulation of extrinsic apoptotic signaling pathway via death domain receptors);GO:1902042(negative regulation of extrinsic apoptotic signaling pathway via death domain receptors);GO:0070534(protein K63-linked ubiquitination);GO:0031996(thioesterase binding);GO:0019899(enzyme binding);GO:0070059(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress);GO:0005164(tumor necrosis factor receptor binding);GO:0010803(regulation of tumor necrosis factor-mediated signaling pathway);GO:0000151(ubiquitin ligase complex);GO:0002726(positive regulation of T cell cytokine production);GO:0032743(positive regulation of interleukin-2 production);GO:0043507(positive regulation of JUN kinase activity);GO:0034976(response to endoplasmic reticulum stress);GO:1901215(negative regulation of neuron death);GO:2001238(positive regulation of extrinsic apoptotic signaling pathway);GO:0071550(death-inducing signaling complex assembly);GO:0060544(regulation of necroptotic process);GO:0070207(protein homotrimerization);GO:0090073(positive regulation of protein homodimerization activity);GO:0046625(sphingolipid binding);GO:0097057(TRAF2-GSTP1 complex);GO:0005622(intracellular);GO:0005622(intracellular)","04141(Protein processing in endoplasmic reticulum);04010(MAPK signaling pathway);04064(NF-kappa B signaling pathway);04668(TNF signaling pathway);04071(Sphingolipid signaling pathway);04210(Apoptosis);04217(Necroptosis);04621(NOD-like receptor signaling pathway);04622(RIG-I-like receptor signaling pathway);04657(IL-17 signaling pathway);04920(Adipocytokine signaling pathway);04380(Osteoclast differentiation);05200(Pathways in cancer);05203(Viral carcinogenesis);05222(Small cell lung cancer);04932(Non-alcoholic fatty liver disease (NAFLD));05160(Hepatitis C);05168(Herpes simplex infection);05167(Kaposi's sarcoma-associated herpesvirus infection);05169(Epstein-Barr virus infection);05169(Epstein-Barr virus infection)","K03173","EC:2.3.2.27","TNF receptor associated factor 2 [Source:HGNC Symbol;Acc:HGNC:12032]",{"v":2.27191487633088,"d":"2.27"},{"v":1.76816694567295,"d":"1.77"},{"v":1.28489839824837,"d":"1.28"},{"v":0.361654284603275,"d":"0.36"},{"v":0.563403051285086,"d":"0.56"},1,"up","no"]
["ENSG00000213866","YBX1P10","ENST00000444752","NA","NA","NA","NA","Y-box binding protein 1 pseudogene 10 [Source:HGNC Symbol;Acc:HGNC:42432]",{"v":4.050568,"d":"4.05"},{"v":3.149086,"d":"3.15"},{"v":1.28626782501335,"d":"1.29"},{"v":0.363191070029006,"d":"0.36"},{"v":0.563939207047651,"d":"0.56"},1,"up","no"]
["ENSG00000139133","ALG10","ENST00000266483;ENST00000538927;ENST00000541178;ENST00000541875","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016740(transferase activity);GO:0016757(transferase activity, transferring glycosyl groups);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0006488(dolichol-linked oligosaccharide biosynthetic process);GO:0006486(protein glycosylation);GO:0004583(dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity);GO:0004583(dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity)","00510(N-Glycan biosynthesis);00510(N-Glycan biosynthesis)","K03850","EC:2.4.1.256","ALG10, alpha-1,2-glucosyltransferase [Source:HGNC Symbol;Acc:HGNC:23162]",{"v":0.357818138300296,"d":"0.36"},{"v":0.479303762588289,"d":"0.48"},{"v":0.746537303124936,"d":"0.75"},{"v":-0.421713743852713,"d":"-0.42"},{"v":0.564772428288929,"d":"0.56"},1,"down","no"]
["ENSG00000014138","POLA2","ENST00000527850;ENST00000532469;ENST00000533192;ENST00000525924;ENST00000527618;ENST00000532391;ENST00000534785;ENST00000265465","GO:0005634(nucleus);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0003677(DNA binding);GO:0006260(DNA replication);GO:0003887(DNA-directed DNA polymerase activity);GO:0071897(DNA biosynthetic process);GO:0003674(molecular_function);GO:0000082(G1/S transition of mitotic cell cycle);GO:0006270(DNA replication initiation);GO:0032201(telomere maintenance via semi-conservative replication);GO:0046982(protein heterodimerization activity);GO:0005658(alpha DNA polymerase:primase complex);GO:0000060(protein import into nucleus, translocation);GO:0000060(protein import into nucleus, translocation)","00230(Purine metabolism);00240(Pyrimidine metabolism);03030(DNA replication);03030(DNA replication)","K02321","NA","DNA polymerase alpha 2, accessory subunit [Source:HGNC Symbol;Acc:HGNC:30073]",{"v":1.11470425305623,"d":"1.11"},{"v":0.86816948323437,"d":"0.87"},{"v":1.28397078517825,"d":"1.28"},{"v":0.360612376480494,"d":"0.36"},{"v":0.56547281895457,"d":"0.57"},1,"up","no"]
["ENSG00000274307","AC023449.2","ENST00000620538","NA","NA","NA","NA",null,{"v":0.91774,"d":"0.92"},{"v":0.712556,"d":"0.71"},{"v":1.28795491161396,"d":"1.29"},{"v":0.36508208884886,"d":"0.37"},{"v":0.567834715306271,"d":"0.57"},1,"up","no"]
["MSTRG.3756","TESC","ENST00000335209;ENST00000470612;ENST00000541210;ENST00000552139;ENST00000462502;ENST00000482176;ENST00000535198;ENST00000549210","GO:0006810(transport);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0015031(protein transport);GO:0046872(metal ion binding);GO:0005829(cytosol);GO:0005509(calcium ion binding);GO:0042803(protein homodimerization activity);GO:0005886(plasma membrane);GO:0042995(cell projection);GO:0005515(protein binding);GO:0043086(negative regulation of catalytic activity);GO:0000287(magnesium ion binding);GO:0030154(cell differentiation);GO:0004860(protein kinase inhibitor activity);GO:0045893(positive regulation of transcription, DNA-templated);GO:0030027(lamellipodium);GO:0050821(protein stabilization);GO:0010628(positive regulation of gene expression);GO:0008285(negative regulation of cell proliferation);GO:0032587(ruffle membrane);GO:0006469(negative regulation of protein kinase activity);GO:0001726(ruffle);GO:0071300(cellular response to retinoic acid);GO:0033628(regulation of cell adhesion mediated by integrin);GO:0032417(positive regulation of sodium:proton antiporter activity);GO:0019212(phosphatase inhibitor activity);GO:0051604(protein maturation);GO:0045654(positive regulation of megakaryocyte differentiation);GO:0072661(protein targeting to plasma membrane);GO:0030854(positive regulation of granulocyte differentiation);GO:0008584(male gonad development);GO:0030219(megakaryocyte differentiation);GO:0030219(megakaryocyte differentiation)","NA","NA","NA","tescalcin [Source:HGNC Symbol;Acc:HGNC:26065]",{"v":19.355024837487,"d":"19.36"},{"v":15.2003860145379,"d":"15.20"},{"v":1.27332456024311,"d":"1.27"},{"v":0.348600197536706,"d":"0.35"},{"v":0.56866794520044,"d":"0.57"},1,"up","no"]
["ENSG00000133027","PEMT","ENST00000255389;ENST00000395783;ENST00000472446;ENST00000580147;ENST00000435340;ENST00000484838;ENST00000421096;ENST00000582268;ENST00000461404;ENST00000490392;ENST00000477595;ENST00000395782","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0008168(methyltransferase activity);GO:0016740(transferase activity);GO:0032259(methylation);GO:0006629(lipid metabolic process);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005739(mitochondrion);GO:0008654(phospholipid biosynthetic process);GO:0006644(phospholipid metabolic process);GO:0031966(mitochondrial membrane);GO:0008170(N-methyltransferase activity);GO:0000773(phosphatidyl-N-methylethanolamine N-methyltransferase activity);GO:0004608(phosphatidylethanolamine N-methyltransferase activity);GO:0080101(phosphatidyl-N-dimethylethanolamine N-methyltransferase activity);GO:0006656(phosphatidylcholine biosynthetic process);GO:0008283(cell proliferation);GO:1903955(positive regulation of protein targeting to mitochondrion);GO:0008429(phosphatidylethanolamine binding);GO:0008757(S-adenosylmethionine-dependent methyltransferase activity);GO:0006650(glycerophospholipid metabolic process);GO:0006686(sphingomyelin biosynthetic process);GO:0007584(response to nutrient);GO:0008285(negative regulation of cell proliferation);GO:0033273(response to vitamin);GO:0042493(response to drug);GO:0043200(response to amino acid);GO:0045471(response to ethanol);GO:0046498(S-adenosylhomocysteine metabolic process);GO:0046500(S-adenosylmethionine metabolic process);GO:0050747(positive regulation of lipoprotein metabolic process);GO:0031526(brush border membrane);GO:0042383(sarcolemma);GO:0042383(sarcolemma)","00564(Glycerophospholipid metabolism);00564(Glycerophospholipid metabolism)","K00551","EC:2.1.1.17;EC:2.1.1.71","phosphatidylethanolamine N-methyltransferase [Source:HGNC Symbol;Acc:HGNC:8830]",{"v":1.44568063837209,"d":"1.45"},{"v":1.12160490523256,"d":"1.12"},{"v":1.28893929727628,"d":"1.29"},{"v":0.366184321433754,"d":"0.37"},{"v":0.569301649334006,"d":"0.57"},1,"up","no"]
["ENSG00000167912","AC090152.1","ENST00000523683;ENST00000518993;ENST00000517898","NA","NA","NA","NA",null,{"v":1.01850603327596,"d":"1.02"},{"v":0.791625484796328,"d":"0.79"},{"v":1.2866008647233,"d":"1.29"},{"v":0.363564563431576,"d":"0.36"},{"v":0.570804910880459,"d":"0.57"},1,"up","no"]
["MSTRG.9741","BPI","ENST00000262865;ENST00000490381;ENST00000451435;ENST00000489039;ENST00000418004","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005615(extracellular space);GO:0008289(lipid binding);GO:0005576(extracellular region);GO:0006955(immune response);GO:0042742(defense response to bacterium);GO:0001530(lipopolysaccharide binding);GO:0050829(defense response to Gram-negative bacterium);GO:0070062(extracellular exosome);GO:0005887(integral component of plasma membrane);GO:0043312(neutrophil degranulation);GO:0032715(negative regulation of interleukin-6 production);GO:0032720(negative regulation of tumor necrosis factor production);GO:0019730(antimicrobial humoral response);GO:0035580(specific granule lumen);GO:0035578(azurophil granule lumen);GO:0032717(negative regulation of interleukin-8 production);GO:0043031(negative regulation of macrophage activation);GO:0005737(cytoplasm);GO:0005737(cytoplasm)","NA","NA","NA","bactericidal/permeability-increasing protein [Source:HGNC Symbol;Acc:HGNC:1095]",{"v":2.20352217152506,"d":"2.20"},{"v":2.90951571329541,"d":"2.91"},{"v":0.757350153311006,"d":"0.76"},{"v":-0.400967624731231,"d":"-0.40"},{"v":0.571464685090656,"d":"0.57"},1,"down","no"]
["ENSG00000196367","TRRAP","ENST00000628380;ENST00000359863;ENST00000417523;ENST00000355540;ENST00000456197","GO:0005634(nucleus);GO:0005794(Golgi apparatus);GO:0005654(nucleoplasm);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0016569(covalent chromatin modification);GO:0016301(kinase activity);GO:0005515(protein binding);GO:0000123(histone acetyltransferase complex);GO:0016310(phosphorylation);GO:0016578(histone deubiquitination);GO:0016573(histone acetylation);GO:0016579(protein deubiquitination);GO:0043967(histone H4 acetylation);GO:1904837(beta-catenin-TCF complex assembly);GO:0033276(transcription factor TFTC complex);GO:0003712(transcription cofactor activity);GO:0036459(thiol-dependent ubiquitinyl hydrolase activity);GO:0006281(DNA repair);GO:0000125(PCAF complex);GO:0030914(STAGA complex);GO:0043968(histone H2A acetylation);GO:0035267(NuA4 histone acetyltransferase complex);GO:0000812(Swr1 complex);GO:0016740(transferase activity);GO:0016740(transferase activity)","05166(HTLV-I infection);05166(HTLV-I infection)","K08874","NA","transformation/transcription domain associated protein [Source:HGNC Symbol;Acc:HGNC:12347]",{"v":3.80544898048116,"d":"3.81"},{"v":2.99951516908761,"d":"3.00"},{"v":1.26868802655154,"d":"1.27"},{"v":0.343337350596952,"d":"0.34"},{"v":0.572658436623743,"d":"0.57"},1,"up","no"]
["MSTRG.8012","ARMC6","ENST00000392335;ENST00000269932;ENST00000537263;ENST00000535612;ENST00000392336;ENST00000546344;ENST00000540792;ENST00000540634;ENST00000545091;ENST00000539985;ENST00000538663;ENST00000535795","GO:0005829(cytosol);GO:0002244(hematopoietic progenitor cell differentiation);GO:0002244(hematopoietic progenitor cell differentiation)","NA","NA","NA","armadillo repeat containing 6 [Source:HGNC Symbol;Acc:HGNC:25049]",{"v":1.776095255923,"d":"1.78"},{"v":2.35803457823297,"d":"2.36"},{"v":0.753210013253472,"d":"0.75"},{"v":-0.40887591546748,"d":"-0.41"},{"v":0.575029632409824,"d":"0.58"},1,"down","no"]
["MSTRG.3515","XPOT","ENST00000332707;ENST00000542958;ENST00000538086;ENST00000540203;ENST00000400935","GO:0003723(RNA binding);GO:0006810(transport);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0006886(intracellular protein transport);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0008536(Ran GTPase binding);GO:0000049(tRNA binding);GO:0005643(nuclear pore);GO:0006409(tRNA export from nucleus);GO:0071528(tRNA re-export from nucleus);GO:0016363(nuclear matrix);GO:0016363(nuclear matrix)","03013(RNA transport);03013(RNA transport)","K14288","NA","exportin for tRNA [Source:HGNC Symbol;Acc:HGNC:12826]",{"v":4.97232292571972,"d":"4.97"},{"v":3.92708358052689,"d":"3.93"},{"v":1.2661617263192,"d":"1.27"},{"v":0.340461691383168,"d":"0.34"},{"v":0.576380490119235,"d":"0.58"},1,"up","no"]
["ENSG00000107679","PLEKHA1","ENST00000368990;ENST00000368988;ENST00000368989;ENST00000433307;ENST00000494222;ENST00000392799;ENST00000481451","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0008289(lipid binding);GO:0070062(extracellular exosome);GO:0032587(ruffle membrane);GO:0043325(phosphatidylinositol-3,4-bisphosphate binding);GO:0006661(phosphatidylinositol biosynthetic process);GO:0014065(phosphatidylinositol 3-kinase signaling);GO:0050853(B cell receptor signaling pathway);GO:0030165(PDZ domain binding);GO:0051898(negative regulation of protein kinase B signaling);GO:0045184(establishment of protein localization);GO:0070301(cellular response to hydrogen peroxide);GO:0031529(ruffle organization);GO:0001553(luteinization);GO:0007283(spermatogenesis);GO:0008209(androgen metabolic process);GO:0008210(estrogen metabolic process);GO:0008585(female gonad development);GO:0009791(post-embryonic development);GO:0033327(Leydig cell differentiation);GO:0035264(multicellular organism growth);GO:0048008(platelet-derived growth factor receptor signaling pathway);GO:0048705(skeletal system morphogenesis);GO:0060021(palate development);GO:0060325(face morphogenesis);GO:0060325(face morphogenesis)","NA","NA","NA","pleckstrin homology domain containing A1 [Source:HGNC Symbol;Acc:HGNC:14335]",{"v":0.400011266363712,"d":"0.40"},{"v":0.528218086884016,"d":"0.53"},{"v":0.757284304146792,"d":"0.76"},{"v":-0.401093067886508,"d":"-0.40"},{"v":0.577335201816225,"d":"0.58"},1,"down","no"]
["ENSG00000205670","SMIM11A","ENST00000399292;ENST00000495363;ENST00000489469;ENST00000474455;ENST00000481710","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0003674(molecular_function);GO:0008150(biological_process);GO:0005575(cellular_component);GO:0005575(cellular_component)","NA","NA","NA","small integral membrane protein 11A [Source:HGNC Symbol;Acc:HGNC:1293]",{"v":0.697225761666667,"d":"0.70"},{"v":0.551849659285714,"d":"0.55"},{"v":1.26343425230908,"d":"1.26"},{"v":0.337350590016253,"d":"0.34"},{"v":0.578452995373748,"d":"0.58"},1,"up","no"]
["MSTRG.8567","OST4","ENST00000447619;ENST00000429985;ENST00000456793","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0006486(protein glycosylation);GO:0018279(protein N-linked glycosylation via asparagine);GO:0008250(oligosaccharyltransferase complex);GO:0008250(oligosaccharyltransferase complex)","NA","NA","NA","oligosaccharyltransferase complex subunit 4, non-catalytic [Source:HGNC Symbol;Acc:HGNC:32483]",{"v":142.698132450626,"d":"142.70"},{"v":113.002330802503,"d":"113.00"},{"v":1.26278928440886,"d":"1.26"},{"v":0.336613923606591,"d":"0.34"},{"v":0.579390475045383,"d":"0.58"},1,"up","no"]
["MSTRG.3048","LTBR","ENST00000441074;ENST00000228918;ENST00000536876;ENST00000544454;ENST00000440421;ENST00000535739;ENST00000444814;ENST00000546296;ENST00000539925;ENST00000543190;ENST00000545445;ENST00000541102;ENST00000541005;ENST00000543542","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005515(protein binding);GO:0006955(immune response);GO:0006915(apoptotic process);GO:0043123(positive regulation of I-kappaB kinase/NF-kappaB signaling);GO:0005886(plasma membrane);GO:0042802(identical protein binding);GO:0005887(integral component of plasma membrane);GO:0006954(inflammatory response);GO:0033209(tumor necrosis factor-mediated signaling pathway);GO:0016032(viral process);GO:0031625(ubiquitin protein ligase binding);GO:0048534(hematopoietic or lymphoid organ development);GO:0007165(signal transduction);GO:0071260(cellular response to mechanical stimulus);GO:0005031(tumor necrosis factor-activated receptor activity);GO:0007275(multicellular organism development);GO:0032496(response to lipopolysaccharide);GO:0042127(regulation of cell proliferation);GO:0046330(positive regulation of JNK cascade);GO:2001238(positive regulation of extrinsic apoptotic signaling pathway);GO:0043011(myeloid dendritic cell differentiation);GO:0043011(myeloid dendritic cell differentiation)","04064(NF-kappa B signaling pathway);04066(HIF-1 signaling pathway);04060(Cytokine-cytokine receptor interaction);04672(Intestinal immune network for IgA production);05203(Viral carcinogenesis);05166(HTLV-I infection);05166(HTLV-I infection)","K03159","NA","lymphotoxin beta receptor [Source:HGNC Symbol;Acc:HGNC:6718]",{"v":5.37487485,"d":"5.37"},{"v":7.04759604570064,"d":"7.05"},{"v":0.762653650286742,"d":"0.76"},{"v":-0.390900071192726,"d":"-0.39"},{"v":0.57967968648006,"d":"0.58"},1,"down","no"]
["MSTRG.2259","EIF4G2","MSTRG.2259.1;ENST00000339995;ENST00000396525;ENST00000532383;ENST00000532152;ENST00000524932;ENST00000534246;ENST00000526148;ENST00000527526;ENST00000527015;ENST00000533485;ENST00000525995;ENST00000525972;ENST00000534470;ENST00000532349;ENST00000525606;ENST00000532082;ENST00000528839;ENST00000534272;ENST00000640650;ENST00000534605;ENST00000530211;ENST00000531507;ENST00000530564;ENST00000530702;ENST00000525681;ENST00000532570;ENST00000528562;ENST00000532120","GO:0003723(RNA binding);GO:0003743(translation initiation factor activity);GO:0006413(translational initiation);GO:0007507(heart development);GO:0045727(positive regulation of translation);GO:0045773(positive regulation of axon extension);GO:0060999(positive regulation of dendritic spine development);GO:0030424(axon);GO:0016020(membrane);GO:0006412(translation);GO:0006446(regulation of translational initiation);GO:0005515(protein binding);GO:0005829(cytosol);GO:0045296(cadherin binding);GO:0006417(regulation of translation);GO:0010507(negative regulation of autophagy);GO:0005913(cell-cell adherens junction);GO:0008135(translation factor activity, RNA binding);GO:0007050(cell cycle arrest);GO:0016281(eukaryotic translation initiation factor 4F complex);GO:0008219(cell death);GO:0030307(positive regulation of cell growth);GO:0034645(cellular macromolecule biosynthetic process);GO:0034645(cellular macromolecule biosynthetic process)","03013(RNA transport);05416(Viral myocarditis);05416(Viral myocarditis)","K03260","NA","eukaryotic translation initiation factor 4 gamma 2 [Source:HGNC Symbol;Acc:HGNC:3297]",{"v":32.5509029400114,"d":"32.55"},{"v":42.5716248627205,"d":"42.57"},{"v":0.7646149998967,"d":"0.76"},{"v":-0.387194592250352,"d":"-0.39"},{"v":0.581455023206151,"d":"0.58"},1,"down","no"]
["ENSG00000268262","AC011445.1","ENST00000601911","NA","NA","NA","NA",null,{"v":1.514935,"d":"1.51"},{"v":2.00859,"d":"2.01"},{"v":0.754228090351938,"d":"0.75"},{"v":-0.40692721190081,"d":"-0.41"},{"v":0.582017389785989,"d":"0.58"},1,"down","no"]
["MSTRG.8000","KXD1","ENST00000222307;ENST00000602094;ENST00000595073;ENST00000539106;ENST00000596785;ENST00000598830;ENST00000540691;ENST00000595870;ENST00000600654;ENST00000601630;ENST00000599000;ENST00000600796;ENST00000600372;ENST00000596244;ENST00000597438;ENST00000600099","GO:0016020(membrane);GO:0005765(lysosomal membrane);GO:0005515(protein binding);GO:0005764(lysosome);GO:0016192(vesicle-mediated transport);GO:0032418(lysosome localization);GO:0031083(BLOC-1 complex);GO:0099078(BORC complex);GO:0099078(BORC complex)","NA","NA","NA","KxDL motif containing 1 [Source:HGNC Symbol;Acc:HGNC:28420]",{"v":7.03542213764591,"d":"7.04"},{"v":9.2016814661965,"d":"9.20"},{"v":0.764580056752822,"d":"0.76"},{"v":-0.387260525370102,"d":"-0.39"},{"v":0.583696480288785,"d":"0.58"},1,"down","no"]
["MSTRG.349","ZCCHC17","ENST00000344147;ENST00000373714;ENST00000546109;ENST00000618216;ENST00000616393;ENST00000615916;ENST00000479629;ENST00000616859;ENST00000627541","GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0005634(nucleus);GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0030529(intracellular ribonucleoprotein complex);GO:0005515(protein binding);GO:0005730(nucleolus);GO:0022625(cytosolic large ribosomal subunit);GO:0022625(cytosolic large ribosomal subunit)","NA","NA","NA","zinc finger CCHC-type containing 17 [Source:HGNC Symbol;Acc:HGNC:30246]",{"v":9.20919680739198,"d":"9.21"},{"v":7.3190919297241,"d":"7.32"},{"v":1.25824308477283,"d":"1.26"},{"v":0.331410668892745,"d":"0.33"},{"v":0.585221084644148,"d":"0.59"},1,"up","no"]
["MSTRG.12935","HLA-DMA;HLA-DMB","ENST00000477541;ENST00000395303;ENST00000418107;ENST00000498020;ENST00000374843;ENST00000456800;ENST00000480785;ENST00000487996;ENST00000475627;ENST00000477537;ENST00000464392;ENST00000395305;ENST00000438510;ENST00000422832;ENST00000414017","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0043231(intracellular membrane-bounded organelle);GO:0006955(immune response);GO:0002376(immune system process);GO:0002504(antigen processing and presentation of peptide or polysaccharide antigen via MHC class II);GO:0019882(antigen processing and presentation);GO:0042613(MHC class II protein complex);GO:0005765(lysosomal membrane);GO:0005764(lysosome);GO:0005768(endosome);GO:0031902(late endosome membrane);GO:0070062(extracellular exosome);GO:0019886(antigen processing and presentation of exogenous peptide antigen via MHC class II);GO:0009986(cell surface);GO:0023026(MHC class II protein complex binding);GO:0002503(peptide antigen assembly with MHC class II protein complex);GO:0042102(positive regulation of T cell proliferation);GO:2001190(positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell);GO:0002399(MHC class II protein complex assembly);GO:0002399(MHC class II protein complex assembly)","04514(Cell adhesion molecules (CAMs));04145(Phagosome);04640(Hematopoietic cell lineage);04612(Antigen processing and presentation);04658(Th1 and Th2 cell differentiation);04659(Th17 cell differentiation);04672(Intestinal immune network for IgA production);05310(Asthma);05322(Systemic lupus erythematosus);05323(Rheumatoid arthritis);05320(Autoimmune thyroid disease);05321(Inflammatiory bowel disease (IBD));05330(Allograft rejection);05332(Graft-versus-host disease);05416(Viral myocarditis);04940(Type I diabetes mellitus);05150(Staphylococcus aureus infection);05152(Tuberculosis);05166(HTLV-I infection);05164(Influenza A);05168(Herpes simplex infection);05145(Toxoplasmosis);05140(Leishmaniasis);05140(Leishmaniasis)","K06752","NA","major histocompatibility complex, class II, DM alpha [Source:HGNC Symbol;Acc:HGNC:4934];major histocompatibility complex, class II, DM beta [Source:HGNC Symbol;Acc:HGNC:4935]",{"v":10.0876987300042,"d":"10.09"},{"v":13.1591371795799,"d":"13.16"},{"v":0.766592717466165,"d":"0.77"},{"v":-0.383467802104207,"d":"-0.38"},{"v":0.585943658136008,"d":"0.59"},1,"down","no"]
["MSTRG.11791","SEC24B","ENST00000504968;ENST00000265175;ENST00000399100","GO:0006810(transport);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0006886(intracellular protein transport);GO:0015031(protein transport);GO:0008270(zinc ion binding);GO:0005794(Golgi apparatus);GO:0006888(ER to Golgi vesicle-mediated transport);GO:0030127(COPII vesicle coat);GO:0005829(cytosol);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0000139(Golgi membrane);GO:0048471(perinuclear region of cytoplasm);GO:0016192(vesicle-mediated transport);GO:0005515(protein binding);GO:0019886(antigen processing and presentation of exogenous peptide antigen via MHC class II);GO:0048208(COPII vesicle coating);GO:0012507(ER to Golgi transport vesicle membrane);GO:0002474(antigen processing and presentation of peptide antigen via MHC class I);GO:0090110(cargo loading into COPII-coated vesicle);GO:0001843(neural tube closure);GO:0002093(auditory receptor cell morphogenesis);GO:0003151(outflow tract morphogenesis);GO:0021747(cochlear nucleus development);GO:0035909(aorta morphogenesis);GO:0060088(auditory receptor cell stereocilium organization);GO:0060425(lung morphogenesis);GO:0060463(lung lobe morphogenesis);GO:0060982(coronary artery morphogenesis);GO:0061156(pulmonary artery morphogenesis);GO:0072358(cardiovascular system development);GO:0090178(regulation of establishment of planar polarity involved in neural tube closure);GO:1901301(regulation of cargo loading into COPII-coated vesicle);GO:0030134(ER to Golgi transport vesicle);GO:0030134(ER to Golgi transport vesicle)","04141(Protein processing in endoplasmic reticulum);04141(Protein processing in endoplasmic reticulum)","K14007","NA","SEC24 homolog B, COPII coat complex component [Source:HGNC Symbol;Acc:HGNC:10704]",{"v":5.74750995305614,"d":"5.75"},{"v":7.49309550526921,"d":"7.49"},{"v":0.767040797626887,"d":"0.77"},{"v":-0.382624780563757,"d":"-0.38"},{"v":0.587102896900319,"d":"0.59"},1,"down","no"]
["MSTRG.944","SCNM1;TNFAIP8L2","ENST00000368905;ENST00000602841;ENST00000459799;ENST00000497147;ENST00000461862;MSTRG.944.1;ENST00000368910;ENST00000368902;ENST00000471039;MSTRG.944.5;MSTRG.944.2","GO:0006397(mRNA processing);GO:0008380(RNA splicing);GO:0005634(nucleus);GO:0016607(nuclear speck);GO:0046872(metal ion binding);GO:0005515(protein binding);GO:0019899(enzyme binding);GO:0002376(immune system process);GO:0045087(innate immune response);GO:0005737(cytoplasm);GO:0050728(negative regulation of inflammatory response);GO:0050868(negative regulation of T cell activation);GO:0019899(enzyme binding)","NA","NA","NA","sodium channel modifier 1 [Source:HGNC Symbol;Acc:HGNC:23136];TNF alpha induced protein 8 like 2 [Source:HGNC Symbol;Acc:HGNC:26277]",{"v":6.85108425795607,"d":"6.85"},{"v":5.44879313110713,"d":"5.45"},{"v":1.25735811455995,"d":"1.26"},{"v":0.330395609597604,"d":"0.33"},{"v":0.587562970644862,"d":"0.59"},1,"up","no"]
["MSTRG.12540","RPL26L1","ENST00000521476;ENST00000519156;ENST00000265100;ENST00000519974;ENST00000519239","GO:0030529(intracellular ribonucleoprotein complex);GO:0005622(intracellular);GO:0003735(structural constituent of ribosome);GO:0006412(translation);GO:0005840(ribosome);GO:0015934(large ribosomal subunit);GO:0003723(RNA binding);GO:0070062(extracellular exosome);GO:0022625(cytosolic large ribosomal subunit);GO:0002181(cytoplasmic translation);GO:0042273(ribosomal large subunit biogenesis);GO:0042273(ribosomal large subunit biogenesis)","03010(Ribosome);03010(Ribosome)","K02898","NA","ribosomal protein L26 like 1 [Source:HGNC Symbol;Acc:HGNC:17050]",{"v":2.39519773024055,"d":"2.40"},{"v":1.9022561975945,"d":"1.90"},{"v":1.25913519602112,"d":"1.26"},{"v":0.332433196605431,"d":"0.33"},{"v":0.589185161898532,"d":"0.59"},1,"up","no"]
["MSTRG.11853","LSM6","ENST00000502781;ENST00000296581;ENST00000503982;ENST00000507449;ENST00000510331","GO:0003723(RNA binding);GO:0006397(mRNA processing);GO:0008380(RNA splicing);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0008033(tRNA processing);GO:0030529(intracellular ribonucleoprotein complex);GO:0005515(protein binding);GO:0005681(spliceosomal complex);GO:0000398(mRNA splicing, via spliceosome);GO:0006364(rRNA processing);GO:0005730(nucleolus);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0000932(P-body);GO:0046540(U4/U6 x U5 tri-snRNP complex);GO:0030490(maturation of SSU-rRNA);GO:0005732(small nucleolar ribonucleoprotein complex);GO:0043928(exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay);GO:0005688(U6 snRNP);GO:0030532(small nuclear ribonucleoprotein complex);GO:0030532(small nuclear ribonucleoprotein complex)","03040(Spliceosome);03018(RNA degradation);03018(RNA degradation)","K12625","NA","LSM6 homolog, U6 small nuclear RNA and mRNA degradation associated [Source:HGNC Symbol;Acc:HGNC:17017]",{"v":3.52470107850514,"d":"3.52"},{"v":4.58790273488839,"d":"4.59"},{"v":0.768259765339355,"d":"0.77"},{"v":-0.380333894875671,"d":"-0.38"},{"v":0.589456003428258,"d":"0.59"},1,"down","no"]
["MSTRG.10831","GORASP1","ENST00000319283;ENST00000431601;ENST00000493851;ENST00000413243;ENST00000479927;ENST00000486133;ENST00000492064;ENST00000452389;ENST00000476334;ENST00000453680;ENST00000470910;ENST00000473827;ENST00000479124;ENST00000466443;ENST00000489587;ENST00000469471;ENST00000441302;ENST00000493938;ENST00000419156;ENST00000488479","GO:0006810(transport);GO:0016020(membrane);GO:0015031(protein transport);GO:0005794(Golgi apparatus);GO:0005515(protein binding);GO:0006487(protein N-linked glycosylation);GO:0007030(Golgi organization);GO:0006888(ER to Golgi vesicle-mediated transport);GO:0000139(Golgi membrane);GO:0048208(COPII vesicle coating);GO:0033116(endoplasmic reticulum-Golgi intermediate compartment membrane);GO:1904668(positive regulation of ubiquitin protein ligase activity);GO:0050774(negative regulation of dendrite morphogenesis);GO:0050774(negative regulation of dendrite morphogenesis)","NA","NA","NA","golgi reassembly stacking protein 1 [Source:HGNC Symbol;Acc:HGNC:16769]",{"v":1.89652358455882,"d":"1.90"},{"v":2.47886367870844,"d":"2.48"},{"v":0.76507780595138,"d":"0.77"},{"v":-0.386321622177146,"d":"-0.39"},{"v":0.591810386871937,"d":"0.59"},1,"down","no"]
["MSTRG.13485","ZDHHC4","ENST00000335965;ENST00000405731;ENST00000493944;ENST00000396713;ENST00000396709;ENST00000396706;ENST00000474738;ENST00000396707;ENST00000474097","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016740(transferase activity);GO:0005794(Golgi apparatus);GO:0016746(transferase activity, transferring acyl groups);GO:0019706(protein-cysteine S-palmitoyltransferase activity);GO:0019706(protein-cysteine S-palmitoyltransferase activity)","NA","NA","NA","zinc finger DHHC-type containing 4 [Source:HGNC Symbol;Acc:HGNC:18471]",{"v":1.59688889991566,"d":"1.60"},{"v":2.07518109277481,"d":"2.08"},{"v":0.769517853393891,"d":"0.77"},{"v":-0.37797329633383,"d":"-0.38"},{"v":0.593070081484579,"d":"0.59"},1,"down","no"]
["ENSG00000173905","GOLIM4","ENST00000309027;ENST00000470487","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005794(Golgi apparatus);GO:0032580(Golgi cisterna membrane);GO:0005768(endosome);GO:0010008(endosome membrane);GO:0000139(Golgi membrane);GO:0005796(Golgi lumen);GO:0005801(cis-Golgi network);GO:0030133(transport vesicle);GO:0030139(endocytic vesicle);GO:0030139(endocytic vesicle)","NA","NA","NA","golgi integral membrane protein 4 [Source:HGNC Symbol;Acc:HGNC:15448]",{"v":1.09465765009684,"d":"1.09"},{"v":0.870967656552615,"d":"0.87"},{"v":1.25682927702461,"d":"1.26"},{"v":0.329788692783463,"d":"0.33"},{"v":0.593939629324927,"d":"0.59"},1,"up","no"]
["ENSG00000099800","TIMM13","ENST00000215570","GO:0006810(transport);GO:0016020(membrane);GO:0015031(protein transport);GO:0046872(metal ion binding);GO:0005739(mitochondrion);GO:0005743(mitochondrial inner membrane);GO:0001650(fibrillar center);GO:0008565(protein transporter activity);GO:0006626(protein targeting to mitochondrion);GO:0008270(zinc ion binding);GO:0007605(sensory perception of sound);GO:0072321(chaperone-mediated protein transport);GO:0042719(mitochondrial intermembrane space protein transporter complex);GO:0045039(protein import into mitochondrial inner membrane)","NA","NA","NA","translocase of inner mitochondrial membrane 13 [Source:HGNC Symbol;Acc:HGNC:11816]",{"v":3.772642,"d":"3.77"},{"v":3.010504,"d":"3.01"},{"v":1.25315960384042,"d":"1.25"},{"v":0.325570169652105,"d":"0.33"},{"v":0.594875075817086,"d":"0.59"},1,"up","no"]
["MSTRG.5871","RNF40","ENST00000567365;ENST00000566703;ENST00000493683;ENST00000602784;ENST00000563683;ENST00000324685;ENST00000564260;ENST00000566811;ENST00000563909;ENST00000565931","GO:0005634(nucleus);GO:0016020(membrane);GO:0046872(metal ion binding);GO:0005654(nucleoplasm);GO:0016740(transferase activity);GO:0016569(covalent chromatin modification);GO:0016567(protein ubiquitination);GO:0004842(ubiquitin-protein transferase activity);GO:0017075(syntaxin-1 binding);GO:0031624(ubiquitin conjugating enzyme binding);GO:0032403(protein complex binding);GO:0006511(ubiquitin-dependent protein catabolic process);GO:0043434(response to peptide hormone);GO:1901800(positive regulation of proteasomal protein catabolic process);GO:1902916(positive regulation of protein polyubiquitination);GO:2001168(positive regulation of histone H2B ubiquitination);GO:0005829(cytosol);GO:0019898(extrinsic component of membrane);GO:0043005(neuron projection);GO:0043234(protein complex);GO:0043679(axon terminus);GO:0042803(protein homodimerization activity);GO:0005515(protein binding);GO:0031625(ubiquitin protein ligase binding);GO:1900364(negative regulation of mRNA polyadenylation);GO:0003730(mRNA 3'-UTR binding);GO:0000151(ubiquitin ligase complex);GO:0010390(histone monoubiquitination);GO:0033523(histone H2B ubiquitination);GO:0033503(HULC complex);GO:0033503(HULC complex)","NA","NA","NA","ring finger protein 40 [Source:HGNC Symbol;Acc:HGNC:16867]",{"v":6.68139749747049,"d":"6.68"},{"v":8.65672266503143,"d":"8.66"},{"v":0.771816050485225,"d":"0.77"},{"v":-0.373671048786552,"d":"-0.37"},{"v":0.59607634306008,"d":"0.60"},1,"down","no"]
["ENSG00000168081","PNOC","ENST00000522209;ENST00000301908;ENST00000518479;ENST00000519592","GO:0005576(extracellular region);GO:0001515(opioid peptide activity);GO:0007218(neuropeptide signaling pathway);GO:0007268(chemical synaptic transmission);GO:0005886(plasma membrane);GO:0007165(signal transduction);GO:0005184(neuropeptide hormone activity);GO:0030425(dendrite);GO:0043679(axon terminus);GO:0043025(neuronal cell body);GO:0007600(sensory perception);GO:0031628(opioid receptor binding);GO:0007565(female pregnancy);GO:0007565(female pregnancy)","NA","NA","NA","prepronociceptin [Source:HGNC Symbol;Acc:HGNC:9163]",{"v":0.903122146284102,"d":"0.90"},{"v":1.18068468720602,"d":"1.18"},{"v":0.764913914841444,"d":"0.76"},{"v":-0.386630702140445,"d":"-0.39"},{"v":0.597601992366353,"d":"0.60"},1,"down","no"]
["MSTRG.7996","ISYNA1","ENST00000578963;ENST00000582811;ENST00000577916;ENST00000581672;ENST00000581800;ENST00000583309;ENST00000583534;ENST00000338128;ENST00000582287","GO:0005737(cytoplasm);GO:0016853(isomerase activity);GO:0006629(lipid metabolic process);GO:0008654(phospholipid biosynthetic process);GO:0005515(protein binding);GO:0006021(inositol biosynthetic process);GO:0004512(inositol-3-phosphate synthase activity);GO:0005829(cytosol);GO:0043647(inositol phosphate metabolic process);GO:0043647(inositol phosphate metabolic process)","00562(Inositol phosphate metabolism);00562(Inositol phosphate metabolism)","K01858","EC:5.5.1.4","inositol-3-phosphate synthase 1 [Source:HGNC Symbol;Acc:HGNC:29821]",{"v":1.07280321193666,"d":"1.07"},{"v":0.854930870280146,"d":"0.85"},{"v":1.25484205709535,"d":"1.25"},{"v":0.327505788251831,"d":"0.33"},{"v":0.598624378654805,"d":"0.60"},1,"up","no"]
["ENSG00000129493","HEATR5A","ENST00000543095;ENST00000549184;ENST00000552500;ENST00000382464;ENST00000550366;ENST00000549719;ENST00000550819;ENST00000551414","NA","NA","NA","NA","HEAT repeat containing 5A [Source:HGNC Symbol;Acc:HGNC:20276]",{"v":0.475839836180806,"d":"0.48"},{"v":0.616690138338377,"d":"0.62"},{"v":0.771602797902556,"d":"0.77"},{"v":-0.374069720146245,"d":"-0.37"},{"v":0.599911320197486,"d":"0.60"},1,"down","no"]
["MSTRG.11640","REST","ENST00000309042;ENST00000503522;ENST00000622863;ENST00000640168;ENST00000619101;ENST00000511065","GO:0005634(nucleus);GO:0003676(nucleic acid binding);GO:0046872(metal ion binding);GO:0006366(transcription from RNA polymerase II promoter);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0000981(RNA polymerase II transcription factor activity, sequence-specific DNA binding);GO:0005515(protein binding);GO:0071805(potassium ion transmembrane transport);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0045893(positive regulation of transcription, DNA-templated);GO:0043065(positive regulation of apoptotic process);GO:0045665(negative regulation of neuron differentiation);GO:0050768(negative regulation of neurogenesis);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0001047(core promoter binding);GO:0005654(nucleoplasm);GO:0008285(negative regulation of cell proliferation);GO:0003682(chromatin binding);GO:0010629(negative regulation of gene expression);GO:0045955(negative regulation of calcium ion-dependent exocytosis);GO:0008134(transcription factor binding);GO:0044212(transcription regulatory region DNA binding);GO:0045892(negative regulation of transcription, DNA-templated);GO:0035690(cellular response to drug);GO:0004407(histone deacetylase activity);GO:0001046(core promoter sequence-specific DNA binding);GO:0043280(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process);GO:0001078(transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0017053(transcriptional repressor complex);GO:0015271(outward rectifier potassium channel activity);GO:0043922(negative regulation by host of viral transcription);GO:0046676(negative regulation of insulin secretion);GO:0071385(cellular response to glucocorticoid stimulus);GO:0001228(transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding);GO:0003677(DNA binding);GO:0002244(hematopoietic progenitor cell differentiation);GO:0032348(negative regulation of aldosterone biosynthetic process);GO:0060379(cardiac muscle cell myoblast differentiation);GO:0070933(histone H4 deacetylation);GO:0071257(cellular response to electrical stimulus);GO:2000065(negative regulation of cortisol biosynthetic process);GO:2000706(negative regulation of dense core granule biogenesis);GO:2000740(negative regulation of mesenchymal stem cell differentiation);GO:2000798(negative regulation of amniotic stem cell differentiation);GO:0005829(cytosol);GO:0005829(cytosol)","04550(Signaling pathways regulating pluripotency of stem cells);05016(Huntington's disease);05016(Huntington's disease)","K09222","NA","RE1 silencing transcription factor [Source:HGNC Symbol;Acc:HGNC:9966]",{"v":2.90597792809721,"d":"2.91"},{"v":3.75210742565452,"d":"3.75"},{"v":0.774492198231848,"d":"0.77"},{"v":-0.368677388640645,"d":"-0.37"},{"v":0.601236521165442,"d":"0.60"},1,"down","no"]
["ENSG00000101004","NINL","ENST00000278886;ENST00000496509;ENST00000489780","GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0005829(cytosol);GO:0005509(calcium ion binding);GO:0045171(intercellular bridge);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0005874(microtubule);GO:0005815(microtubule organizing center);GO:0000086(G2/M transition of mitotic cell cycle);GO:0010389(regulation of G2/M transition of mitotic cell cycle);GO:0097711(ciliary basal body docking);GO:0097711(ciliary basal body docking)","NA","NA","NA","ninein like [Source:HGNC Symbol;Acc:HGNC:29163]",{"v":0.274831684753662,"d":"0.27"},{"v":0.21672832689747,"d":"0.22"},{"v":1.26809304850897,"d":"1.27"},{"v":0.342660609591886,"d":"0.34"},{"v":0.601801460198391,"d":"0.60"},1,"up","no"]
["MSTRG.9474","SP140","ENST00000417495;ENST00000392045;ENST00000343805;ENST00000441657;ENST00000479539;ENST00000473711;ENST00000420434;ENST00000456542;ENST00000486750;ENST00000538494;ENST00000544128;ENST00000543928;ENST00000373645","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0005739(mitochondrion);GO:0003677(DNA binding);GO:0001650(fibrillar center);GO:0005515(protein binding);GO:0006355(regulation of transcription, DNA-templated);GO:0016604(nuclear body);GO:0005635(nuclear envelope);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0016605(PML body);GO:0005654(nucleoplasm);GO:0006952(defense response);GO:0006952(defense response)","NA","NA","NA","SP140 nuclear body protein [Source:HGNC Symbol;Acc:HGNC:17133]",{"v":3.71891555374418,"d":"3.72"},{"v":2.99112160551774,"d":"2.99"},{"v":1.2433180740241,"d":"1.24"},{"v":0.314195423594594,"d":"0.31"},{"v":0.60381983384032,"d":"0.60"},1,"up","no"]
["ENSG00000144476","ACKR3","ENST00000272928;ENST00000447924","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0004930(G-protein coupled receptor activity);GO:0007186(G-protein coupled receptor signaling pathway);GO:0004871(signal transducer activity);GO:0007165(signal transduction);GO:0006935(chemotaxis);GO:0001525(angiogenesis);GO:0015026(coreceptor activity);GO:0019956(chemokine binding);GO:0001570(vasculogenesis);GO:0005737(cytoplasm);GO:0043231(intracellular membrane-bounded organelle);GO:0007155(cell adhesion);GO:0005886(plasma membrane);GO:0007275(multicellular organism development);GO:0048471(perinuclear region of cytoplasm);GO:0005905(clathrin-coated pit);GO:0005515(protein binding);GO:0005768(endosome);GO:0005044(scavenger receptor activity);GO:0005769(early endosome);GO:0016032(viral process);GO:0055037(recycling endosome);GO:0070374(positive regulation of ERK1 and ERK2 cascade);GO:0009986(cell surface);GO:1902230(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage);GO:0031623(receptor internalization);GO:0019958(C-X-C chemokine binding);GO:0070098(chemokine-mediated signaling pathway);GO:0016494(C-X-C chemokine receptor activity);GO:1905322(positive regulation of mesenchymal stem cell migration);GO:0005634(nucleus);GO:0005634(nucleus)","04060(Cytokine-cytokine receptor interaction);04060(Cytokine-cytokine receptor interaction)","K04304","NA","atypical chemokine receptor 3 [Source:HGNC Symbol;Acc:HGNC:23692]",{"v":0.854424146589903,"d":"0.85"},{"v":0.682741701062888,"d":"0.68"},{"v":1.25146031838943,"d":"1.25"},{"v":0.32361254642345,"d":"0.32"},{"v":0.604929249347806,"d":"0.60"},1,"up","no"]
["ENSG00000275835","TUBGCP5","ENST00000613552;ENST00000612085;ENST00000615383;ENST00000615455;ENST00000614508;ENST00000620238;ENST00000610294;ENST00000620435","GO:0005737(cytoplasm);GO:0005856(cytoskeleton);GO:0005874(microtubule);GO:0000226(microtubule cytoskeleton organization);GO:0005815(microtubule organizing center);GO:0043015(gamma-tubulin binding);GO:0007020(microtubule nucleation);GO:0000922(spindle pole);GO:0005829(cytosol);GO:0005813(centrosome);GO:0008017(microtubule binding);GO:0005200(structural constituent of cytoskeleton);GO:0031122(cytoplasmic microtubule organization);GO:0090307(mitotic spindle assembly);GO:0008274(gamma-tubulin ring complex);GO:0051415(interphase microtubule nucleation by interphase microtubule organizing center);GO:0000923(equatorial microtubule organizing center);GO:0051298(centrosome duplication);GO:0051321(meiotic cell cycle);GO:0051011(microtubule minus-end binding);GO:0051011(microtubule minus-end binding)","NA","NA","NA","tubulin gamma complex associated protein 5 [Source:HGNC Symbol;Acc:HGNC:18600]",{"v":0.518338972831121,"d":"0.52"},{"v":0.415830714572399,"d":"0.42"},{"v":1.24651439796633,"d":"1.25"},{"v":0.317899546892513,"d":"0.32"},{"v":0.605562853096139,"d":"0.61"},1,"up","no"]
["ENSG00000135362","PRR5L","ENST00000378867;ENST00000527487;ENST00000532578;ENST00000529020;ENST00000524380;ENST00000530627;ENST00000525672;ENST00000527172;ENST00000532843;ENST00000389693;ENST00000526679;ENST00000530252;ENST00000529034;ENST00000526682;ENST00000532121;ENST00000530050;ENST00000530639;ENST00000527751","GO:0005515(protein binding);GO:0031625(ubiquitin protein ligase binding);GO:0034599(cellular response to oxidative stress);GO:0061014(positive regulation of mRNA catabolic process);GO:0001933(negative regulation of protein phosphorylation);GO:0009968(negative regulation of signal transduction);GO:0090316(positive regulation of intracellular protein transport);GO:0031932(TORC2 complex);GO:0010762(regulation of fibroblast migration);GO:0038203(TORC2 signaling);GO:0001934(positive regulation of protein phosphorylation);GO:0014068(positive regulation of phosphatidylinositol 3-kinase signaling);GO:0005739(mitochondrion);GO:0005739(mitochondrion)","NA","NA","NA","proline rich 5 like [Source:HGNC Symbol;Acc:HGNC:25878]",{"v":3.42268385459492,"d":"3.42"},{"v":2.75258951813785,"d":"2.75"},{"v":1.24344143289131,"d":"1.24"},{"v":0.314338557038439,"d":"0.31"},{"v":0.607166324317695,"d":"0.61"},1,"up","no"]
["ENSG00000127955","GNAI1","ENST00000351004;ENST00000490206","GO:0006810(transport);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005525(GTP binding);GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0007186(G-protein coupled receptor signaling pathway);GO:0005730(nucleolus);GO:0007165(signal transduction);GO:0003924(GTPase activity);GO:0004871(signal transducer activity);GO:0005765(lysosomal membrane);GO:0051301(cell division);GO:0005813(centrosome);GO:0005886(plasma membrane);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0007049(cell cycle);GO:0019001(guanyl nucleotide binding);GO:0031683(G-protein beta/gamma-subunit complex binding);GO:0007188(adenylate cyclase-modulating G-protein coupled receptor signaling pathway);GO:0000287(magnesium ion binding);GO:0005815(microtubule organizing center);GO:0030496(midbody);GO:0070062(extracellular exosome);GO:0005938(cell cortex);GO:0006457(protein folding);GO:0007193(adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway);GO:0019003(GDP binding);GO:0001664(G-protein coupled receptor binding);GO:0099738(cell cortex region);GO:1904322(cellular response to forskolin);GO:1904778(positive regulation of protein localization to cell cortex);GO:0005834(heterotrimeric G-protein complex);GO:0031821(G-protein coupled serotonin receptor binding);GO:0043434(response to peptide hormone);GO:0060236(regulation of mitotic spindle organization);GO:0032794(GTPase activating protein binding);GO:0043949(regulation of cAMP-mediated signaling);GO:0050805(negative regulation of synaptic transmission);GO:0005622(intracellular);GO:0043234(protein complex);GO:0045121(membrane raft);GO:0045121(membrane raft)","04015(Rap1 signaling pathway);04371(Apelin signaling pathway);04071(Sphingolipid signaling pathway);04024(cAMP signaling pathway);04022(cGMP - PKG signaling pathway);04540(Gap junction);04611(Platelet activation);04670(Leukocyte transendothelial migration);04062(Chemokine signaling pathway);04923(Regulation of lipolysis in adipocyte);04915(Estrogen signaling pathway);04914(Progesterone-mediated oocyte maturation);04921(Oxytocin signaling pathway);04926(Relaxin signaling pathway);04916(Melanogenesis);04924(Renin secretion);04261(Adrenergic signaling in cardiomyocytes);04971(Gastric acid secretion);04724(Glutamatergic synapse);04727(GABAergic synapse);04725(Cholinergic synapse);04728(Dopaminergic synapse);04726(Serotonergic synapse);04730(Long-term depression);04723(Retrograde endocannabinoid signaling);04360(Axon guidance);04713(Circadian entrainment);05200(Pathways in cancer);05012(Parkinson's disease);05030(Cocaine addiction);05032(Morphine addiction);05034(Alcoholism);05133(Pertussis);05145(Toxoplasmosis);05142(Chagas disease (American trypanosomiasis));05142(Chagas disease (American trypanosomiasis))","K04630","NA","G protein subunit alpha i1 [Source:HGNC Symbol;Acc:HGNC:4384]",{"v":0.190670572245437,"d":"0.19"},{"v":0.150407422696283,"d":"0.15"},{"v":1.26769389985797,"d":"1.27"},{"v":0.342206431227644,"d":"0.34"},{"v":0.609083533558192,"d":"0.61"},1,"up","no"]
["MSTRG.5928","AC007342.7","ENST00000624610","NA","NA","NA","NA",null,{"v":0.398321,"d":"0.40"},{"v":0.310992,"d":"0.31"},{"v":1.28080786644029,"d":"1.28"},{"v":0.357054073709742,"d":"0.36"},{"v":0.609951700835007,"d":"0.61"},1,"up","no"]
["ENSG00000167785","ZNF558","ENST00000597304;ENST00000301475;ENST00000599938;ENST00000595786;ENST00000596172;ENST00000593891;ENST00000601372","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0005622(intracellular);GO:0008150(biological_process);GO:0005575(cellular_component);GO:0005575(cellular_component)","NA","NA","NA","zinc finger protein 558 [Source:HGNC Symbol;Acc:HGNC:26422]",{"v":0.448974521016618,"d":"0.45"},{"v":0.359402866813294,"d":"0.36"},{"v":1.24922353846959,"d":"1.25"},{"v":0.321031658679747,"d":"0.32"},{"v":0.611865018561038,"d":"0.61"},1,"up","no"]
["MSTRG.8476","UBE2M","ENST00000253023;ENST00000593801;ENST00000599829;ENST00000596985","GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0016567(protein ubiquitination);GO:0016874(ligase activity);GO:0005515(protein binding);GO:0043525(positive regulation of neuron apoptotic process);GO:0005737(cytoplasm);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0038061(NIK/NF-kappaB signaling);GO:0043687(post-translational protein modification);GO:0004842(ubiquitin-protein transferase activity);GO:0006464(cellular protein modification process);GO:0007179(transforming growth factor beta receptor signaling pathway);GO:0018169(ribosomal S6-glutamic acid ligase activity);GO:0019788(NEDD8 transferase activity);GO:0045116(protein neddylation);GO:0045116(protein neddylation)","04120(Ubiquitin mediated proteolysis);04120(Ubiquitin mediated proteolysis)","K10579","NA","ubiquitin conjugating enzyme E2 M [Source:HGNC Symbol;Acc:HGNC:12491]",{"v":12.4093817935554,"d":"12.41"},{"v":15.9224164320044,"d":"15.92"},{"v":0.77936548428744,"d":"0.78"},{"v":-0.359628054514586,"d":"-0.36"},{"v":0.612388753112198,"d":"0.61"},1,"down","no"]
["MSTRG.5529","RPS2","ENST00000526908;ENST00000531065;MSTRG.5529.1;ENST00000533186;ENST00000343262;ENST00000526522;ENST00000530225;ENST00000529806;ENST00000533872;ENST00000533161;ENST00000526586;ENST00000527871;ENST00000527826;ENST00000534461;ENST00000563194","GO:0003723(RNA binding);GO:0005634(nucleus);GO:0016020(membrane);GO:0006412(translation);GO:0030529(intracellular ribonucleoprotein complex);GO:0003735(structural constituent of ribosome);GO:0005840(ribosome);GO:0015935(small ribosomal subunit);GO:0005515(protein binding);GO:0022627(cytosolic small ribosomal subunit);GO:0005654(nucleoplasm);GO:0005925(focal adhesion);GO:0003729(mRNA binding);GO:0005829(cytosol);GO:0045296(cadherin binding);GO:0070062(extracellular exosome);GO:0019899(enzyme binding);GO:0006413(translational initiation);GO:0006364(rRNA processing);GO:0000184(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay);GO:0019083(viral transcription);GO:0006479(protein methylation);GO:0006614(SRP-dependent cotranslational protein targeting to membrane);GO:0017134(fibroblast growth factor binding);GO:0051347(positive regulation of transferase activity);GO:0051347(positive regulation of transferase activity)","03010(Ribosome);03010(Ribosome)","K02981","NA","ribosomal protein S2 [Source:HGNC Symbol;Acc:HGNC:10404]",{"v":287.394755357613,"d":"287.39"},{"v":232.728770248971,"d":"232.73"},{"v":1.23489139331661,"d":"1.23"},{"v":0.304384164714014,"d":"0.30"},{"v":0.613080049569917,"d":"0.61"},1,"up","no"]
["MSTRG.11928","RWDD4","ENST00000512740;ENST00000510702;ENST00000506467;ENST00000510968;ENST00000514322;ENST00000326397","NA","NA","NA","NA","RWD domain containing 4 [Source:HGNC Symbol;Acc:HGNC:23750]",{"v":1.59967922586455,"d":"1.60"},{"v":2.0611668278098,"d":"2.06"},{"v":0.776103711878758,"d":"0.78"},{"v":-0.365678640135473,"d":"-0.37"},{"v":0.614737999749993,"d":"0.61"},1,"down","no"]
["ENSG00000106344","RBM28","ENST00000223073;ENST00000495327;ENST00000459726;ENST00000488249;ENST00000478061;ENST00000415472","GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0006397(mRNA processing);GO:0008380(RNA splicing);GO:0005634(nucleus);GO:0005730(nucleolus);GO:0005681(spliceosomal complex);GO:0005681(spliceosomal complex)","03008(Ribosome biogenesis in eukaryotes);03008(Ribosome biogenesis in eukaryotes)","K14573","NA","RNA binding motif protein 28 [Source:HGNC Symbol;Acc:HGNC:21863]",{"v":1.17964289676037,"d":"1.18"},{"v":0.954256900479012,"d":"0.95"},{"v":1.23619006178338,"d":"1.24"},{"v":0.305900571812129,"d":"0.31"},{"v":0.616356417904901,"d":"0.62"},1,"up","no"]
["MSTRG.9126","UBXN4","ENST00000272638;ENST00000426921;ENST00000490163;ENST00000471246;ENST00000467065;MSTRG.9126.2;ENST00000415164;ENST00000416538;ENST00000470687","GO:0005634(nucleus);GO:0016020(membrane);GO:0005783(endoplasmic reticulum);GO:0005829(cytosol);GO:0005789(endoplasmic reticulum membrane);GO:0005515(protein binding);GO:0006986(response to unfolded protein);GO:0030433(ubiquitin-dependent ERAD pathway);GO:0005635(nuclear envelope);GO:0005635(nuclear envelope)","NA","NA","NA","UBX domain protein 4 [Source:HGNC Symbol;Acc:HGNC:14860]",{"v":7.10949595031299,"d":"7.11"},{"v":9.09716055575117,"d":"9.10"},{"v":0.781507142447696,"d":"0.78"},{"v":-0.355669036343442,"d":"-0.36"},{"v":0.616797372251988,"d":"0.62"},1,"down","no"]
["MSTRG.8462","ZNF552","ENST00000391701;ENST00000596248;ENST00000600397;ENST00000594473","GO:0003676(nucleic acid binding);GO:0006355(regulation of transcription, DNA-templated);GO:0005622(intracellular);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0045892(negative regulation of transcription, DNA-templated);GO:0045892(negative regulation of transcription, DNA-templated)","NA","NA","NA","zinc finger protein 552 [Source:HGNC Symbol;Acc:HGNC:26135]",{"v":2.35042009100033,"d":"2.35"},{"v":3.00675724723988,"d":"3.01"},{"v":0.78171262184799,"d":"0.78"},{"v":-0.355289762590274,"d":"-0.36"},{"v":0.618593175661875,"d":"0.62"},1,"down","no"]
["MSTRG.3898","MICU2","ENST00000479790;ENST00000382374;ENST00000478700;ENST00000460488;ENST00000476895;ENST00000469058;ENST00000480341","GO:0005634(nucleus);GO:0005739(mitochondrion);GO:0005743(mitochondrial inner membrane);GO:0005509(calcium ion binding);GO:0005515(protein binding);GO:0046982(protein heterodimerization activity);GO:0006851(mitochondrial calcium ion transmembrane transport);GO:0051561(positive regulation of mitochondrial calcium ion concentration);GO:0034704(calcium channel complex);GO:0005758(mitochondrial intermembrane space);GO:0051560(mitochondrial calcium ion homeostasis);GO:0036444(mitochondrial calcium uptake);GO:0051562(negative regulation of mitochondrial calcium ion concentration);GO:1990246(uniplex complex);GO:1990246(uniplex complex)","NA","NA","NA","mitochondrial calcium uptake 2 [Source:HGNC Symbol;Acc:HGNC:31830]",{"v":3.48910925980796,"d":"3.49"},{"v":4.45776108587106,"d":"4.46"},{"v":0.782704409813874,"d":"0.78"},{"v":-0.353460521738598,"d":"-0.35"},{"v":0.619243848653532,"d":"0.62"},1,"down","no"]
["MSTRG.7100","ERN1","ENST00000606895;ENST00000433197;ENST00000579249;ENST00000583028;ENST00000583896;ENST00000583077;ENST00000584041;ENST00000577567","GO:1904707(positive regulation of vascular smooth muscle cell proliferation);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0016787(hydrolase activity);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005515(protein binding);GO:0003824(catalytic activity);GO:0008152(metabolic process);GO:0006397(mRNA processing);GO:0006915(apoptotic process);GO:0090502(RNA phosphodiester bond hydrolysis, endonucleolytic);GO:0000287(magnesium ion binding);GO:0042802(identical protein binding);GO:0004540(ribonuclease activity);GO:0006986(response to unfolded protein);GO:0007050(cell cycle arrest);GO:0030176(integral component of endoplasmic reticulum membrane);GO:0019899(enzyme binding);GO:0042803(protein homodimerization activity);GO:0036498(IRE1-mediated unfolded protein response);GO:0035924(cellular response to vascular endothelial growth factor stimulus);GO:0071333(cellular response to glucose stimulus);GO:0016241(regulation of macroautophagy);GO:0030544(Hsp70 protein binding);GO:0034976(response to endoplasmic reticulum stress);GO:0033120(positive regulation of RNA splicing);GO:0004519(endonuclease activity);GO:0004521(endoribonuclease activity);GO:0005161(platelet-derived growth factor receptor binding);GO:0043531(ADP binding);GO:0051879(Hsp90 protein binding);GO:0001935(endothelial cell proliferation);GO:0006379(mRNA cleavage);GO:0006402(mRNA catabolic process);GO:0006987(activation of signaling protein activity involved in unfolded protein response);GO:0007257(activation of JUN kinase activity);GO:0030968(endoplasmic reticulum unfolded protein response);GO:0036289(peptidyl-serine autophosphorylation);GO:0046777(protein autophosphorylation);GO:0070054(mRNA splicing, via endonucleolytic cleavage and ligation);GO:0070055(mRNA endonucleolytic cleavage involved in unfolded protein response);GO:0070059(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress);GO:1900103(positive regulation of endoplasmic reticulum unfolded protein response);GO:1901142(insulin metabolic process);GO:1990579(peptidyl-serine trans-autophosphorylation);GO:0005637(nuclear inner membrane);GO:0005739(mitochondrion);GO:1990332(Ire1 complex);GO:1990597(AIP1-IRE1 complex);GO:1990604(IRE1-TRAF2-ASK1 complex);GO:1990630(IRE1-RACK1-PP2A complex);GO:1990630(IRE1-RACK1-PP2A complex)","04141(Protein processing in endoplasmic reticulum);04140(Autophagy - animal);04210(Apoptosis);05010(Alzheimer's disease);04932(Non-alcoholic fatty liver disease (NAFLD));04932(Non-alcoholic fatty liver disease (NAFLD))","K08852","EC:2.7.11.1;EC:3.1.26.-","endoplasmic reticulum to nucleus signaling 1 [Source:HGNC Symbol;Acc:HGNC:3449]",{"v":6.06588588816274,"d":"6.07"},{"v":7.73131276564801,"d":"7.73"},{"v":0.784586792958999,"d":"0.78"},{"v":-0.349995044321861,"d":"-0.35"},{"v":0.621372157593672,"d":"0.62"},1,"down","no"]
["MSTRG.4864","NSMCE3","ENST00000332303","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005694(chromosome);GO:0005515(protein binding);GO:0006281(DNA repair);GO:0006310(DNA recombination);GO:0006974(cellular response to DNA damage stimulus);GO:0000781(chromosome, telomeric region);GO:0005654(nucleoplasm);GO:0040008(regulation of growth);GO:0031398(positive regulation of protein ubiquitination);GO:0046983(protein dimerization activity);GO:0034644(cellular response to UV);GO:0072711(cellular response to hydroxyurea);GO:0071478(cellular response to radiation);GO:0030915(Smc5-Smc6 complex)","NA","NA","NA","NSE3 homolog, SMC5-SMC6 complex component [Source:HGNC Symbol;Acc:HGNC:7677]",{"v":2.957654,"d":"2.96"},{"v":2.405139,"d":"2.41"},{"v":1.22972268962418,"d":"1.23"},{"v":0.298333015230968,"d":"0.30"},{"v":0.62320701302694,"d":"0.62"},1,"up","no"]
["ENSG00000141026","MED9","ENST00000268711;ENST00000585041;ENST00000624097;ENST00000580462","GO:0005634(nucleus);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0001104(RNA polymerase II transcription cofactor activity);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0016592(mediator complex);GO:0005515(protein binding);GO:0005515(protein binding)","NA","NA","NA","mediator complex subunit 9 [Source:HGNC Symbol;Acc:HGNC:25487]",{"v":0.861242523674558,"d":"0.86"},{"v":0.697999034844948,"d":"0.70"},{"v":1.23387351655275,"d":"1.23"},{"v":0.303194512481997,"d":"0.30"},{"v":0.623841436923283,"d":"0.62"},1,"up","no"]
["ENSG00000174840","PDE12","ENST00000311180;ENST00000487257","GO:0006397(mRNA processing);GO:0046872(metal ion binding);GO:0016787(hydrolase activity);GO:0005739(mitochondrion);GO:0090305(nucleic acid phosphodiester bond hydrolysis);GO:0004527(exonuclease activity);GO:0004518(nuclease activity);GO:0005759(mitochondrial matrix);GO:0004535(poly(A)-specific ribonuclease activity);GO:0090503(RNA phosphodiester bond hydrolysis, exonucleolytic);GO:0090503(RNA phosphodiester bond hydrolysis, exonucleolytic)","NA","NA","NA","phosphodiesterase 12 [Source:HGNC Symbol;Acc:HGNC:25386]",{"v":0.943317281770426,"d":"0.94"},{"v":1.20398385291159,"d":"1.20"},{"v":0.783496622059511,"d":"0.78"},{"v":-0.352001040162062,"d":"-0.35"},{"v":0.625378003478479,"d":"0.63"},1,"down","no"]
["MSTRG.10163","SNAP29","ENST00000215730;ENST00000490458;ENST00000439214","GO:0005737(cytoplasm);GO:0006810(transport);GO:0016020(membrane);GO:0015031(protein transport);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0005794(Golgi apparatus);GO:0005813(centrosome);GO:0005886(plasma membrane);GO:0042995(cell projection);GO:0005515(protein binding);GO:0000139(Golgi membrane);GO:0006914(autophagy);GO:0031410(cytoplasmic vesicle);GO:0098793(presynapse);GO:0019905(syntaxin binding);GO:0060271(cilium assembly);GO:0005929(cilium);GO:0000421(autophagosome membrane);GO:0030030(cell projection organization);GO:0005776(autophagosome);GO:0060170(ciliary membrane);GO:0043312(neutrophil degranulation);GO:0006903(vesicle targeting);GO:0016082(synaptic vesicle priming);GO:0031629(synaptic vesicle fusion to presynaptic active zone membrane);GO:0061025(membrane fusion);GO:0031201(SNARE complex);GO:0035577(azurophil granule membrane);GO:0006887(exocytosis);GO:0005484(SNAP receptor activity);GO:0016240(autophagosome docking);GO:0097352(autophagosome maturation);GO:0020018(ciliary pocket membrane);GO:0020018(ciliary pocket membrane)","04130(SNARE interactions in vesicular transport);04140(Autophagy - animal);04140(Autophagy - animal)","K08509","NA","synaptosome associated protein 29 [Source:HGNC Symbol;Acc:HGNC:11133]",{"v":7.15537431496063,"d":"7.16"},{"v":5.8355669067232,"d":"5.84"},{"v":1.22616609994084,"d":"1.23"},{"v":0.294154423832631,"d":"0.29"},{"v":0.625811470248397,"d":"0.63"},1,"up","no"]
["MSTRG.1105","IFI16","ENST00000368131;ENST00000493884;ENST00000368132;ENST00000562225;MSTRG.1105.7;ENST00000295809;MSTRG.1105.4;ENST00000474473;ENST00000567661;ENST00000447473;ENST00000483916;ENST00000566111;ENST00000340979;ENST00000448393","GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005730(nucleolus);GO:0005829(cytosol);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0006915(apoptotic process);GO:0006914(autophagy);GO:0002376(immune system process);GO:0045087(innate immune response);GO:0006954(inflammatory response);GO:0051607(defense response to virus);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:0001047(core promoter binding);GO:0001078(transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0001819(positive regulation of cytokine production);GO:0008283(cell proliferation);GO:0045071(negative regulation of viral genome replication);GO:0045824(negative regulation of innate immune response);GO:0003690(double-stranded DNA binding);GO:0008134(transcription factor binding);GO:0045892(negative regulation of transcription, DNA-templated);GO:0010506(regulation of autophagy);GO:0030097(hemopoiesis);GO:0032481(positive regulation of type I interferon production);GO:0002218(activation of innate immune response);GO:0032731(positive regulation of interleukin-1 beta production);GO:0071479(cellular response to ionizing radiation);GO:0042149(cellular response to glucose starvation);GO:0072332(intrinsic apoptotic signaling pathway by p53 class mediator);GO:0097202(activation of cysteine-type endopeptidase activity);GO:0040029(regulation of gene expression, epigenetic);GO:0042771(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator);GO:0043392(negative regulation of DNA binding);GO:0030224(monocyte differentiation);GO:0005654(nucleoplasm);GO:2000117(negative regulation of cysteine-type endopeptidase activity);GO:0016607(nuclear speck);GO:0030099(myeloid cell differentiation);GO:0030099(myeloid cell differentiation)","04621(NOD-like receptor signaling pathway);04621(NOD-like receptor signaling pathway)","K20914","NA","interferon gamma inducible protein 16 [Source:HGNC Symbol;Acc:HGNC:5395]",{"v":26.5785414622055,"d":"26.58"},{"v":33.7500167670123,"d":"33.75"},{"v":0.787511948384681,"d":"0.79"},{"v":-0.34462628218801,"d":"-0.34"},{"v":0.627057147999435,"d":"0.63"},1,"down","no"]
["MSTRG.2296","TSG101","MSTRG.2296.5;ENST00000251968;ENST00000438874;ENST00000542488;ENST00000584526;ENST00000535077;MSTRG.2296.2;ENST00000536719;ENST00000543054;ENST00000545247;ENST00000544804;ENST00000543087;ENST00000540555","GO:0006810(transport);GO:0015031(protein transport);GO:0005730(nucleolus);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0006464(cellular protein modification process);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0051301(cell division);GO:0042803(protein homodimerization activity);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0007049(cell cycle);GO:0005815(microtubule organizing center);GO:0030496(midbody);GO:0005768(endosome);GO:0031902(late endosome membrane);GO:0070062(extracellular exosome);GO:0040008(regulation of growth);GO:0048306(calcium-dependent protein binding);GO:0016197(endosomal transport);GO:0016236(macroautophagy);GO:0019058(viral life cycle);GO:0036258(multivesicular body assembly);GO:0039702(viral budding via host ESCRT complex);GO:0075733(intracellular transport of virus);GO:0000813(ESCRT I complex);GO:0010008(endosome membrane);GO:0043657(host cell);GO:0005769(early endosome);GO:0016032(viral process);GO:0031625(ubiquitin protein ligase binding);GO:0031901(early endosome membrane);GO:0043130(ubiquitin binding);GO:0048524(positive regulation of viral process);GO:0003677(DNA binding);GO:0003714(transcription corepressor activity);GO:0032403(protein complex binding);GO:1903543(positive regulation of exosomal secretion);GO:0005770(late endosome);GO:0043405(regulation of MAP kinase activity);GO:1902188(positive regulation of viral release from host cell);GO:0007175(negative regulation of epidermal growth factor-activated receptor activity);GO:0043162(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway);GO:0046790(virion binding);GO:0046755(viral budding);GO:1903551(regulation of extracellular exosome assembly);GO:1903772(regulation of viral budding via host ESCRT complex);GO:0030374(ligand-dependent nuclear receptor transcription coactivator activity);GO:0001558(regulation of cell growth);GO:0006513(protein monoubiquitination);GO:0007050(cell cycle arrest);GO:0008285(negative regulation of cell proliferation);GO:0008333(endosome to lysosome transport);GO:0030154(cell differentiation);GO:0030216(keratinocyte differentiation);GO:0042059(negative regulation of epidermal growth factor receptor signaling pathway);GO:0045892(negative regulation of transcription, DNA-templated);GO:0097352(autophagosome maturation);GO:1903774(positive regulation of viral budding via host ESCRT complex);GO:1990182(exosomal secretion);GO:2000397(positive regulation of ubiquitin-dependent endocytosis);GO:0005771(multivesicular body);GO:0005771(multivesicular body)","04144(Endocytosis);04144(Endocytosis)","K12183","NA","tumor susceptibility 101 [Source:HGNC Symbol;Acc:HGNC:15971]",{"v":7.88534044554903,"d":"7.89"},{"v":10.0101019753728,"d":"10.01"},{"v":0.787738273291203,"d":"0.79"},{"v":-0.344211722243154,"d":"-0.34"},{"v":0.62847356225275,"d":"0.63"},1,"down","no"]
["ENSG00000226259","GTF2H2B","ENST00000508065;ENST00000513202;ENST00000504712;ENST00000507549","NA","NA","NA","NA","general transcription factor IIH subunit 2B (pseudogene) [Source:HGNC Symbol;Acc:HGNC:31393]",{"v":0.454037652173913,"d":"0.45"},{"v":0.593346528524755,"d":"0.59"},{"v":0.765214980363655,"d":"0.77"},{"v":-0.386062977757431,"d":"-0.39"},{"v":0.62926270144976,"d":"0.63"},1,"down","no"]
["MSTRG.14717","APTX;TCEA1P4","ENST00000379819;ENST00000379813;ENST00000486724;ENST00000309615;ENST00000460940;ENST00000379825;ENST00000477119;ENST00000473221;ENST00000482687;ENST00000415066;ENST00000436040;ENST00000480031;ENST00000464632;ENST00000485479;ENST00000468275;ENST00000465003;ENST00000478279;ENST00000473270;ENST00000397172;ENST00000495360;ENST00000496030;ENST00000479656;ENST00000460945;ENST00000474658;ENST00000476858;ENST00000483148;ENST00000379817;ENST00000467331","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0005730(nucleolus);GO:0016787(hydrolase activity);GO:0003677(DNA binding);GO:0003824(catalytic activity);GO:0000790(nuclear chromatin);GO:0016311(dephosphorylation);GO:0006281(DNA repair);GO:0090305(nucleic acid phosphodiester bond hydrolysis);GO:0005515(protein binding);GO:0006974(cellular response to DNA damage stimulus);GO:0005654(nucleoplasm);GO:0033699(DNA 5'-adenosine monophosphate hydrolase activity);GO:0003682(chromatin binding);GO:0008967(phosphoglycolate phosphatase activity);GO:0003690(double-stranded DNA binding);GO:0031647(regulation of protein stability);GO:0047485(protein N-terminus binding);GO:0000785(chromatin);GO:0042542(response to hydrogen peroxide);GO:0051219(phosphoprotein binding);GO:0003725(double-stranded RNA binding);GO:0003684(damaged DNA binding);GO:0000012(single strand break repair);GO:0006266(DNA ligation);GO:0006266(DNA ligation)","NA","NA","NA","aprataxin [Source:HGNC Symbol;Acc:HGNC:15984];transcription elongation factor A1 pseudogene 4 [Source:HGNC Symbol;Acc:HGNC:31091]",{"v":0.938882587645735,"d":"0.94"},{"v":1.21172825588055,"d":"1.21"},{"v":0.774829325873448,"d":"0.77"},{"v":-0.368049536543077,"d":"-0.37"},{"v":0.629986620558759,"d":"0.63"},1,"down","no"]
["MSTRG.1231","SOAT1","ENST00000540564;ENST00000367619;ENST00000539888;ENST00000426956","GO:0042632(cholesterol homeostasis);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005783(endoplasmic reticulum);GO:0016740(transferase activity);GO:0016746(transferase activity, transferring acyl groups);GO:0006629(lipid metabolic process);GO:0005789(endoplasmic reticulum membrane);GO:0008202(steroid metabolic process);GO:0005515(protein binding);GO:0008203(cholesterol metabolic process);GO:0008374(O-acyltransferase activity);GO:0000062(fatty-acyl-CoA binding);GO:0033344(cholesterol efflux);GO:0034383(low-density lipoprotein particle clearance);GO:0034379(very-low-density lipoprotein particle assembly);GO:0015485(cholesterol binding);GO:0034736(cholesterol O-acyltransferase activity);GO:0010742(macrophage derived foam cell differentiation);GO:0034435(cholesterol esterification);GO:0004772(sterol O-acyltransferase activity);GO:0010878(cholesterol storage);GO:0042986(positive regulation of amyloid precursor protein biosynthetic process);GO:0042986(positive regulation of amyloid precursor protein biosynthetic process)","00100(Steroid biosynthesis);04979(Cholesterol metabolism);04979(Cholesterol metabolism)","K00637","EC:2.3.1.26","sterol O-acyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:11177]",{"v":3.56559030906495,"d":"3.57"},{"v":4.52118716516774,"d":"4.52"},{"v":0.788640279379512,"d":"0.79"},{"v":-0.342560697684017,"d":"-0.34"},{"v":0.631326473641162,"d":"0.63"},1,"down","no"]
["MSTRG.4720","XRCC3","ENST00000554811;ENST00000556980;ENST00000557439;ENST00000553332;ENST00000555055;ENST00000555231;ENST00000554170;ENST00000554913;ENST00000553264","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0003677(DNA binding);GO:0008094(DNA-dependent ATPase activity);GO:0005739(mitochondrion);GO:0006281(DNA repair);GO:0005515(protein binding);GO:0006310(DNA recombination);GO:0006974(cellular response to DNA damage stimulus);GO:0048471(perinuclear region of cytoplasm);GO:0003690(double-stranded DNA binding);GO:0000784(nuclear chromosome, telomeric region);GO:0003697(single-stranded DNA binding);GO:0000400(four-way junction DNA binding);GO:0000724(double-strand break repair via homologous recombination);GO:0090267(positive regulation of mitotic cell cycle spindle assembly checkpoint);GO:0000150(recombinase activity);GO:0000707(meiotic DNA recombinase assembly);GO:0000731(DNA synthesis involved in DNA repair);GO:0000732(strand displacement);GO:0010212(response to ionizing radiation);GO:0042148(strand invasion);GO:0005657(replication fork);GO:0008821(crossover junction endodeoxyribonuclease activity);GO:0007131(reciprocal meiotic recombination);GO:0033065(Rad51C-XRCC3 complex);GO:0000722(telomere maintenance via recombination);GO:0010824(regulation of centrosome duplication);GO:0036297(interstrand cross-link repair);GO:0071140(resolution of mitotic recombination intermediates);GO:0090656(t-circle formation);GO:0090657(telomeric loop disassembly);GO:0090737(telomere maintenance via telomere trimming);GO:0033063(Rad51B-Rad51C-Rad51D-XRCC2 complex);GO:0010033(response to organic substance);GO:0010033(response to organic substance)","03440(Homologous recombination);03440(Homologous recombination)","K10880","NA","X-ray repair cross complementing 3 [Source:HGNC Symbol;Acc:HGNC:12830]",{"v":0.595809174104169,"d":"0.60"},{"v":0.48474041761023,"d":"0.48"},{"v":1.22913038083663,"d":"1.23"},{"v":0.297637958680204,"d":"0.30"},{"v":0.633236006450471,"d":"0.63"},1,"up","no"]
["ENSG00000111880","RNGTT","ENST00000369485;ENST00000538899;ENST00000627296;ENST00000369475","GO:0005634(nucleus);GO:0006397(mRNA processing);GO:0000166(nucleotide binding);GO:0016740(transferase activity);GO:0016787(hydrolase activity);GO:0005525(GTP binding);GO:0004725(protein tyrosine phosphatase activity);GO:0008138(protein tyrosine/serine/threonine phosphatase activity);GO:0016791(phosphatase activity);GO:0016311(dephosphorylation);GO:0035335(peptidyl-tyrosine dephosphorylation);GO:0003824(catalytic activity);GO:0008152(metabolic process);GO:0016779(nucleotidyltransferase activity);GO:0006470(protein dephosphorylation);GO:0005654(nucleoplasm);GO:0016032(viral process);GO:0006370(7-methylguanosine mRNA capping);GO:0006366(transcription from RNA polymerase II promoter);GO:0006396(RNA processing);GO:0004484(mRNA guanylyltransferase activity);GO:0004651(polynucleotide 5'-phosphatase activity);GO:0008192(RNA guanylyltransferase activity);GO:0050355(triphosphatase activity);GO:0098507(polynucleotide 5' dephosphorylation);GO:0098507(polynucleotide 5' dephosphorylation)","03015(mRNA surveillance pathway);03015(mRNA surveillance pathway)","K13917","EC:2.7.7.50;EC:3.6.1.-","RNA guanylyltransferase and 5'-phosphatase [Source:HGNC Symbol;Acc:HGNC:10073]",{"v":2.23007069914565,"d":"2.23"},{"v":2.82672911045566,"d":"2.83"},{"v":0.788922677768076,"d":"0.79"},{"v":-0.342044186115028,"d":"-0.34"},{"v":0.633312128367489,"d":"0.63"},1,"down","no"]
["MSTRG.3850","DNAH10","ENST00000409039;ENST00000545078;ENST00000540041","GO:0005524(ATP binding);GO:0003777(microtubule motor activity);GO:0007018(microtubule-based movement);GO:0016887(ATPase activity);GO:0030286(dynein complex);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005930(axoneme);GO:0005737(cytoplasm);GO:0000166(nucleotide binding);GO:0005856(cytoskeleton);GO:0042995(cell projection);GO:0005874(microtubule);GO:0003774(motor activity);GO:0005929(cilium);GO:0051959(dynein light intermediate chain binding);GO:0045503(dynein light chain binding);GO:0045505(dynein intermediate chain binding);GO:0008569(ATP-dependent microtubule motor activity, minus-end-directed);GO:0008569(ATP-dependent microtubule motor activity, minus-end-directed)","05016(Huntington's disease);05016(Huntington's disease)","NA","NA","dynein axonemal heavy chain 10 [Source:HGNC Symbol;Acc:HGNC:2941]",{"v":0.073910526076555,"d":"0.07"},{"v":0.0599434958133971,"d":"0.06"},{"v":1.23300326538574,"d":"1.23"},{"v":0.302176620462223,"d":"0.30"},{"v":0.634656944100385,"d":"0.63"},1,"up","no"]
["MSTRG.1963","SLK","ENST00000335753;ENST00000474260;ENST00000369755","GO:0005737(cytoplasm);GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0042803(protein homodimerization activity);GO:0006915(apoptotic process);GO:0048471(perinuclear region of cytoplasm);GO:0042802(identical protein binding);GO:0005515(protein binding);GO:0045296(cadherin binding);GO:0031252(cell leading edge);GO:0070062(extracellular exosome);GO:0030334(regulation of cell migration);GO:0042981(regulation of apoptotic process);GO:0046777(protein autophosphorylation);GO:0007346(regulation of mitotic cell cycle);GO:0051893(regulation of focal adhesion assembly);GO:0031098(stress-activated protein kinase signaling cascade);GO:0023014(signal transduction by protein phosphorylation);GO:0032147(activation of protein kinase activity);GO:0031122(cytoplasmic microtubule organization);GO:0031122(cytoplasmic microtubule organization)","04114(Oocyte meiosis);04114(Oocyte meiosis)","K08836","EC:2.7.11.1","STE20 like kinase [Source:HGNC Symbol;Acc:HGNC:11088]",{"v":4.36964432844244,"d":"4.37"},{"v":5.52193560885377,"d":"5.52"},{"v":0.791324752399545,"d":"0.79"},{"v":-0.337658209891813,"d":"-0.34"},{"v":0.635750212870855,"d":"0.64"},1,"down","no"]
["MSTRG.11118","TIMMDC1","ENST00000494664;ENST00000486418;ENST00000463927;ENST00000492164;ENST00000466984;ENST00000469324;ENST00000493694","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005739(mitochondrion);GO:0005515(protein binding);GO:0031966(mitochondrial membrane);GO:0032981(mitochondrial respiratory chain complex I assembly);GO:0005743(mitochondrial inner membrane);GO:0005743(mitochondrial inner membrane)","NA","NA","NA","translocase of inner mitochondrial membrane domain containing 1 [Source:HGNC Symbol;Acc:HGNC:1321]",{"v":3.11166594871795,"d":"3.11"},{"v":3.94128686117216,"d":"3.94"},{"v":0.789505067335424,"d":"0.79"},{"v":-0.340979569021956,"d":"-0.34"},{"v":0.636354925170419,"d":"0.64"},1,"down","no"]
["MSTRG.7212","SLC25A19","ENST00000580994;ENST00000416858;ENST00000584438;ENST00000580273;ENST00000579228;ENST00000402418;ENST00000581988;ENST00000579207;ENST00000375261;ENST00000320362;ENST00000580151","GO:0006810(transport);GO:0005634(nucleus);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0055085(transmembrane transport);GO:0005743(mitochondrial inner membrane);GO:0005739(mitochondrion);GO:0071934(thiamine transmembrane transport);GO:0006839(mitochondrial transport);GO:0042723(thiamine-containing compound metabolic process);GO:0031305(integral component of mitochondrial inner membrane);GO:0015234(thiamine transmembrane transporter activity);GO:0030233(deoxynucleotide transmembrane transporter activity);GO:0090422(thiamine pyrophosphate transporter activity);GO:0030302(deoxynucleotide transport);GO:0030974(thiamine pyrophosphate transport);GO:0030974(thiamine pyrophosphate transport)","NA","NA","NA","solute carrier family 25 member 19 [Source:HGNC Symbol;Acc:HGNC:14409]",{"v":1.00199096200241,"d":"1.00"},{"v":1.2767223645959,"d":"1.28"},{"v":0.784815077880737,"d":"0.78"},{"v":-0.349575335982087,"d":"-0.35"},{"v":0.638412297726817,"d":"0.64"},1,"down","no"]
["MSTRG.9751","ZHX3","ENST00000309060;ENST00000432768;ENST00000559296;ENST00000441102;ENST00000559234;ENST00000561291;ENST00000421422;ENST00000560361;ENST00000560364","GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0003677(DNA binding);GO:0003676(nucleic acid binding);GO:0046872(metal ion binding);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0042803(protein homodimerization activity);GO:0005515(protein binding);GO:0030154(cell differentiation);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0003714(transcription corepressor activity);GO:0045892(negative regulation of transcription, DNA-templated);GO:0046982(protein heterodimerization activity);GO:0045669(positive regulation of osteoblast differentiation);GO:0000977(RNA polymerase II regulatory region sequence-specific DNA binding);GO:0000977(RNA polymerase II regulatory region sequence-specific DNA binding)","NA","NA","NA","zinc fingers and homeoboxes 3 [Source:HGNC Symbol;Acc:HGNC:15935]",{"v":0.435384605971947,"d":"0.44"},{"v":0.35748184941055,"d":"0.36"},{"v":1.21792087259773,"d":"1.22"},{"v":0.284420405478143,"d":"0.28"},{"v":0.639309273806691,"d":"0.64"},1,"up","no"]
["MSTRG.8410","RPS9","ENST00000302907;ENST00000484121;ENST00000445961;ENST00000402367;ENST00000626547;ENST00000391751;ENST00000495002;ENST00000391752;ENST00000391753;ENST00000436445;ENST00000448962;ENST00000460761;ENST00000441429","GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0006412(translation);GO:0030529(intracellular ribonucleoprotein complex);GO:0005622(intracellular);GO:0003735(structural constituent of ribosome);GO:0005840(ribosome);GO:0015935(small ribosomal subunit);GO:0005515(protein binding);GO:0022627(cytosolic small ribosomal subunit);GO:0019843(rRNA binding);GO:0005730(nucleolus);GO:0005925(focal adhesion);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0008284(positive regulation of cell proliferation);GO:0006413(translational initiation);GO:0006364(rRNA processing);GO:0000184(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay);GO:0019083(viral transcription);GO:0006614(SRP-dependent cotranslational protein targeting to membrane);GO:0045182(translation regulator activity);GO:0045903(positive regulation of translational fidelity);GO:0045903(positive regulation of translational fidelity)","03010(Ribosome);03010(Ribosome)","K02997","NA","ribosomal protein S9 [Source:HGNC Symbol;Acc:HGNC:10442]",{"v":28.4820830253946,"d":"28.48"},{"v":35.8595968297872,"d":"35.86"},{"v":0.794266682935365,"d":"0.79"},{"v":-0.3323046069768,"d":"-0.33"},{"v":0.640698452247093,"d":"0.64"},1,"down","no"]
["MSTRG.953","PSMB4","ENST00000290541;MSTRG.953.2;ENST00000495805;ENST00000466425;ENST00000493673;ENST00000495288;ENST00000476467;ENST00000474100","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016787(hydrolase activity);GO:0005515(protein binding);GO:0008233(peptidase activity);GO:0006508(proteolysis);GO:0000502(proteasome complex);GO:0004175(endopeptidase activity);GO:0004298(threonine-type endopeptidase activity);GO:0051603(proteolysis involved in cellular protein catabolic process);GO:0005839(proteasome core complex);GO:0038095(Fc-epsilon receptor signaling pathway);GO:0001530(lipopolysaccharide binding);GO:0002862(negative regulation of inflammatory response to antigenic stimulus);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0000165(MAPK cascade);GO:0000209(protein polyubiquitination);GO:0002223(stimulatory C-type lectin receptor signaling pathway);GO:0002479(antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent);GO:0006521(regulation of cellular amino acid metabolic process);GO:0010972(negative regulation of G2/M transition of mitotic cell cycle);GO:0016579(protein deubiquitination);GO:0031145(anaphase-promoting complex-dependent catabolic process);GO:0031146(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process);GO:0033209(tumor necrosis factor-mediated signaling pathway);GO:0038061(NIK/NF-kappaB signaling);GO:0043161(proteasome-mediated ubiquitin-dependent protein catabolic process);GO:0043488(regulation of mRNA stability);GO:0043687(post-translational protein modification);GO:0050852(T cell receptor signaling pathway);GO:0051437(positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition);GO:0055085(transmembrane transport);GO:0060071(Wnt signaling pathway, planar cell polarity pathway);GO:0061418(regulation of transcription from RNA polymerase II promoter in response to hypoxia);GO:0090090(negative regulation of canonical Wnt signaling pathway);GO:0090263(positive regulation of canonical Wnt signaling pathway);GO:1902036(regulation of hematopoietic stem cell differentiation);GO:0019774(proteasome core complex, beta-subunit complex);GO:0016032(viral process);GO:0051436(negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle);GO:0051436(negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle)","03050(Proteasome);03050(Proteasome)","K02736","EC:3.4.25.1","proteasome subunit beta 4 [Source:HGNC Symbol;Acc:HGNC:9541]",{"v":21.7994800370714,"d":"21.80"},{"v":27.4456826784059,"d":"27.45"},{"v":0.794277201718983,"d":"0.79"},{"v":-0.332285500929924,"d":"-0.33"},{"v":0.641776229992539,"d":"0.64"},1,"down","no"]
["MSTRG.4478","YBX1P1","ENST00000445822","NA","NA","NA","NA","Y-box binding protein 1 pseudogene 1 [Source:HGNC Symbol;Acc:HGNC:8015]",{"v":149.102448,"d":"149.10"},{"v":122.96431,"d":"122.96"},{"v":1.21256686594671,"d":"1.21"},{"v":0.278064305658428,"d":"0.28"},{"v":0.641869057717824,"d":"0.64"},1,"up","no"]
["MSTRG.5813","MAZ;MVP;PAGR1;AC120114.5;PRRT2","MSTRG.5813.1;ENST00000545521;ENST00000395353;ENST00000219782;ENST00000322945;MSTRG.5813.42;ENST00000320330;ENST00000568544;ENST00000357402;MSTRG.5813.45;ENST00000563096;ENST00000565777;ENST00000563915;ENST00000563012;ENST00000566066;ENST00000566554;ENST00000569978;ENST00000566252;MSTRG.5813.54;ENST00000568068;ENST00000562557;ENST00000569612;ENST00000562285;ENST00000568411;ENST00000570234;ENST00000562337;ENST00000567444;ENST00000300797;ENST00000616501;ENST00000565830;ENST00000569887;ENST00000562463;ENST00000561855;ENST00000565164;ENST00000563558;ENST00000566859","GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0006367(transcription initiation from RNA polymerase II promoter);GO:0000979(RNA polymerase II core promoter sequence-specific DNA binding);GO:0006369(termination of RNA polymerase II transcription);GO:0005737(cytoplasm);GO:0030529(intracellular ribonucleoprotein complex);GO:0006810(transport);GO:0051028(mRNA transport);GO:0016020(membrane);GO:0015031(protein transport);GO:0005829(cytosol);GO:0005856(cytoskeleton);GO:0048471(perinuclear region of cytoplasm);GO:0005643(nuclear pore);GO:0005576(extracellular region);GO:0042802(identical protein binding);GO:0070062(extracellular exosome);GO:0019901(protein kinase binding);GO:0043312(neutrophil degranulation);GO:0019903(protein phosphatase binding);GO:0034774(secretory granule lumen);GO:1904813(ficolin-1-rich granule lumen);GO:0061099(negative regulation of protein tyrosine kinase activity);GO:0038127(ERBB signaling pathway);GO:0023057(negative regulation of signaling);GO:0031953(negative regulation of protein autophosphorylation);GO:0006281(DNA repair);GO:0006310(DNA recombination);GO:0006974(cellular response to DNA damage stimulus);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0030331(estrogen receptor binding);GO:0035097(histone methyltransferase complex);GO:0033148(positive regulation of intracellular estrogen receptor signaling pathway);GO:0044666(MLL3/4 complex);GO:1902808(positive regulation of cell cycle G1/S phase transition);GO:0016021(integral component of membrane);GO:0005886(plasma membrane);GO:0030054(cell junction);GO:0045202(synapse);GO:0009607(response to biotic stimulus);GO:0050884(neuromuscular process controlling posture);GO:0017124(SH3 domain binding);GO:0043005(neuron projection);GO:0031953(negative regulation of protein autophosphorylation)","NA","NA","NA","MYC associated zinc finger protein [Source:HGNC Symbol;Acc:HGNC:6914];major vault protein [Source:HGNC Symbol;Acc:HGNC:7531];PAXIP1 associated glutamate rich protein 1 [Source:HGNC Symbol;Acc:HGNC:28707];proline rich transmembrane protein 2 [Source:HGNC Symbol;Acc:HGNC:30500]",{"v":10.0995135776076,"d":"10.10"},{"v":12.691021222484,"d":"12.69"},{"v":0.795799912438475,"d":"0.80"},{"v":-0.329522354594822,"d":"-0.33"},{"v":0.64387881692286,"d":"0.64"},1,"down","no"]
["ENSG00000251158","AC131392.2","ENST00000505635","NA","NA","NA","NA",null,{"v":0.483095,"d":"0.48"},{"v":0.615936,"d":"0.62"},{"v":0.784326618349958,"d":"0.78"},{"v":-0.350473531686381,"d":"-0.35"},{"v":0.644302023974335,"d":"0.64"},1,"down","no"]
["ENSG00000153208","MERTK","ENST00000295408;ENST00000616902","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0004713(protein tyrosine kinase activity);GO:0018108(peptidyl-tyrosine phosphorylation);GO:0004714(transmembrane receptor protein tyrosine kinase activity);GO:0005615(extracellular space);GO:0050900(leukocyte migration);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0005887(integral component of plasma membrane);GO:0007267(cell-cell signaling);GO:0007166(cell surface receptor signaling pathway);GO:0050766(positive regulation of phagocytosis);GO:0006909(phagocytosis);GO:0001779(natural killer cell differentiation);GO:0001818(negative regulation of cytokine production);GO:0007283(spermatogenesis);GO:0030168(platelet activation);GO:0032940(secretion by cell);GO:0034446(substrate adhesion-dependent cell spreading);GO:0043277(apoptotic cell clearance);GO:0043491(protein kinase B signaling);GO:0051250(negative regulation of lymphocyte activation);GO:0060041(retina development in camera-type eye);GO:0060068(vagina development);GO:0097350(neutrophil clearance);GO:2000107(negative regulation of leukocyte apoptotic process);GO:0001750(photoreceptor outer segment);GO:0016028(rhabdomere);GO:0016028(rhabdomere)","NA","NA","NA","MER proto-oncogene, tyrosine kinase [Source:HGNC Symbol;Acc:HGNC:7027]",{"v":0.590191228085106,"d":"0.59"},{"v":0.747128033191489,"d":"0.75"},{"v":0.789946571224212,"d":"0.79"},{"v":-0.34017301632743,"d":"-0.34"},{"v":0.64576530827169,"d":"0.65"},1,"down","no"]
["ENSG00000172197","MBOAT1","ENST00000324607","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016740(transferase activity);GO:0016746(transferase activity, transferring acyl groups);GO:0006629(lipid metabolic process);GO:0008654(phospholipid biosynthetic process);GO:0005789(endoplasmic reticulum membrane);GO:0003841(1-acylglycerol-3-phosphate O-acyltransferase activity);GO:0006644(phospholipid metabolic process);GO:0036150(phosphatidylserine acyl-chain remodeling);GO:0036152(phosphatidylethanolamine acyl-chain remodeling);GO:0047144(2-acylglycerol-3-phosphate O-acyltransferase activity)","00561(Glycerolipid metabolism);00564(Glycerophospholipid metabolism)","K13517","EC:2.3.1.51;EC:2.3.1.-","membrane bound O-acyltransferase domain containing 1 [Source:HGNC Symbol;Acc:HGNC:21579]",{"v":2.563586,"d":"2.56"},{"v":3.232729,"d":"3.23"},{"v":0.793009868751757,"d":"0.79"},{"v":-0.334589274972448,"d":"-0.33"},{"v":0.646460731201047,"d":"0.65"},1,"down","no"]
["MSTRG.13263","SERINC1","ENST00000339697","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0006629(lipid metabolic process);GO:0006665(sphingolipid metabolic process);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005515(protein binding);GO:0008654(phospholipid biosynthetic process);GO:0006658(phosphatidylserine metabolic process);GO:0070062(extracellular exosome);GO:0005886(plasma membrane);GO:0015194(L-serine transmembrane transporter activity);GO:0015825(L-serine transport);GO:0030674(protein binding, bridging);GO:1904219(positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity);GO:1904222(positive regulation of serine C-palmitoyltransferase activity);GO:0019899(enzyme binding);GO:0044091(membrane biogenesis)","NA","NA","NA","serine incorporator 1 [Source:HGNC Symbol;Acc:HGNC:13464]",{"v":26.825544,"d":"26.83"},{"v":33.627316,"d":"33.63"},{"v":0.797730749608443,"d":"0.80"},{"v":-0.326026205271244,"d":"-0.33"},{"v":0.647228541659968,"d":"0.65"},1,"down","no"]
["ENSG00000156500","FAM122C","ENST00000494709;ENST00000370784;ENST00000623326;ENST00000460216;ENST00000414371;ENST00000482240;ENST00000463842;ENST00000495147;ENST00000475361","NA","NA","NA","NA","family with sequence similarity 122C [Source:HGNC Symbol;Acc:HGNC:25202]",{"v":0.308638244485918,"d":"0.31"},{"v":0.257021363420428,"d":"0.26"},{"v":1.2008272012045,"d":"1.20"},{"v":0.26402856244963,"d":"0.26"},{"v":0.647811601829766,"d":"0.65"},1,"up","no"]
["MSTRG.370","LCK","ENST00000373564;MSTRG.370.3;ENST00000336890;ENST00000333070;ENST00000619559;ENST00000373557;ENST00000469765;ENST00000482949;ENST00000469956;ENST00000476457;ENST00000477031;ENST00000373562;ENST00000461712;ENST00000355928;ENST00000495610","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0004713(protein tyrosine kinase activity);GO:0018108(peptidyl-tyrosine phosphorylation);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0004715(non-membrane spanning protein tyrosine kinase activity);GO:0006470(protein dephosphorylation);GO:0045121(membrane raft);GO:0050900(leukocyte migration);GO:0045087(innate immune response);GO:0050853(B cell receptor signaling pathway);GO:0046854(phosphatidylinositol phosphorylation);GO:0042802(identical protein binding);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0019901(protein kinase binding);GO:0042169(SH2 domain binding);GO:0050862(positive regulation of T cell receptor signaling pathway);GO:0050852(T cell receptor signaling pathway);GO:0050870(positive regulation of T cell activation);GO:0016032(viral process);GO:0008022(protein C-terminus binding);GO:0019903(protein phosphatase binding);GO:0042127(regulation of cell proliferation);GO:0030168(platelet activation);GO:0046934(phosphatidylinositol-4,5-bisphosphate 3-kinase activity);GO:0014066(regulation of phosphatidylinositol 3-kinase signaling);GO:0030217(T cell differentiation);GO:0038111(interleukin-7-mediated signaling pathway);GO:0048015(phosphatidylinositol-mediated signaling);GO:2001244(positive regulation of intrinsic apoptotic signaling pathway);GO:0016477(cell migration);GO:0001784(phosphotyrosine residue binding);GO:0030097(hemopoiesis);GO:0001772(immunological synapse);GO:0006919(activation of cysteine-type endopeptidase activity involved in apoptotic process);GO:0042609(CD4 receptor binding);GO:0004722(protein serine/threonine phosphatase activity);GO:0031295(T cell costimulation);GO:0050690(regulation of defense response to virus by virus);GO:0038083(peptidyl-tyrosine autophosphorylation);GO:0031234(extrinsic component of cytoplasmic side of plasma membrane);GO:0051117(ATPase binding);GO:0007169(transmembrane receptor protein tyrosine kinase signaling pathway);GO:0042493(response to drug);GO:0051209(release of sequestered calcium ion into cytosol);GO:0000242(pericentriolar material);GO:0043548(phosphatidylinositol 3-kinase binding);GO:0042608(T cell receptor binding);GO:0042610(CD8 receptor binding);GO:0006882(cellular zinc ion homeostasis);GO:0051249(regulation of lymphocyte activation);GO:0051249(regulation of lymphocyte activation)","04064(NF-kappa B signaling pathway);04650(Natural killer cell mediated cytotoxicity);04660(T cell receptor signaling pathway);04658(Th1 and Th2 cell differentiation);04659(Th17 cell differentiation);04380(Osteoclast differentiation);05340(Primary immunodeficiency);05166(HTLV-I infection);05166(HTLV-I infection)","K05856","EC:2.7.10.2","LCK proto-oncogene, Src family tyrosine kinase [Source:HGNC Symbol;Acc:HGNC:6524]",{"v":36.7766002398922,"d":"36.78"},{"v":30.4635211114106,"d":"30.46"},{"v":1.20723405890585,"d":"1.21"},{"v":0.271705413364103,"d":"0.27"},{"v":0.648725065008916,"d":"0.65"},1,"up","no"]
["MSTRG.2996","VPS26B","ENST00000281187;ENST00000531741;ENST00000525918;ENST00000530402;ENST00000527586;ENST00000532160","GO:0006810(transport);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0015031(protein transport);GO:0005829(cytosol);GO:0005515(protein binding);GO:0042147(retrograde transport, endosome to Golgi);GO:0005769(early endosome);GO:0005770(late endosome);GO:0030904(retromer complex);GO:0006886(intracellular protein transport);GO:0005768(endosome);GO:0008565(protein transporter activity);GO:0016241(regulation of macroautophagy);GO:0030906(retromer, cargo-selective complex);GO:0016021(integral component of membrane);GO:0016021(integral component of membrane)","04144(Endocytosis);04144(Endocytosis)","K18466","NA","VPS26, retromer complex component B [Source:HGNC Symbol;Acc:HGNC:28119]",{"v":6.7988260899275,"d":"6.80"},{"v":5.63604407172605,"d":"5.64"},{"v":1.20631173273373,"d":"1.21"},{"v":0.27060277386666,"d":"0.27"},{"v":0.650070383073524,"d":"0.65"},1,"up","no"]
["MSTRG.15099","SEC16A","ENST00000467838;MSTRG.15099.1;ENST00000431893;ENST00000290037;ENST00000313050;ENST00000371706;ENST00000277537;ENST00000472305;ENST00000313084","GO:0048208(COPII vesicle coating);GO:0000139(Golgi membrane);GO:0006810(transport);GO:0016020(membrane);GO:0015031(protein transport);GO:0005794(Golgi apparatus);GO:0005783(endoplasmic reticulum);GO:0005829(cytosol);GO:0005789(endoplasmic reticulum membrane);GO:0005515(protein binding);GO:0016192(vesicle-mediated transport);GO:0021762(substantia nigra development);GO:0007029(endoplasmic reticulum organization);GO:0007029(endoplasmic reticulum organization)","NA","NA","NA","SEC16 homolog A, endoplasmic reticulum export factor [Source:HGNC Symbol;Acc:HGNC:29006]",{"v":8.87804882072385,"d":"8.88"},{"v":7.36195763341596,"d":"7.36"},{"v":1.20593587504855,"d":"1.21"},{"v":0.270153194792672,"d":"0.27"},{"v":0.650737915378856,"d":"0.65"},1,"up","no"]
["MSTRG.9943","FP236383.3","MSTRG.9943.1","NA","NA","NA","NA",null,{"v":55.071583,"d":"55.07"},{"v":45.70586,"d":"45.71"},{"v":1.20491295864469,"d":"1.20"},{"v":0.268928931793656,"d":"0.27"},{"v":0.65255864602776,"d":"0.65"},1,"up","no"]
["MSTRG.9282","UBE2E3","ENST00000410062;ENST00000392415;ENST00000602970;ENST00000602499;ENST00000602888;ENST00000602475;ENST00000602479;ENST00000602837;ENST00000602710;ENST00000602303;ENST00000602632;ENST00000602291;ENST00000602959;ENST00000602762","GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016740(transferase activity);GO:0016567(protein ubiquitination);GO:0005515(protein binding);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0040008(regulation of growth);GO:0004842(ubiquitin-protein transferase activity);GO:0070534(protein K63-linked ubiquitination);GO:0070936(protein K48-linked ubiquitination);GO:0070979(protein K11-linked ubiquitination);GO:0061631(ubiquitin conjugating enzyme activity);GO:0061631(ubiquitin conjugating enzyme activity)","04120(Ubiquitin mediated proteolysis);04120(Ubiquitin mediated proteolysis)","K20217","EC:2.3.2.23","ubiquitin conjugating enzyme E2 E3 [Source:HGNC Symbol;Acc:HGNC:12479]",{"v":4.62377871005718,"d":"4.62"},{"v":5.78371443289606,"d":"5.78"},{"v":0.799447960943315,"d":"0.80"},{"v":-0.322923968539432,"d":"-0.32"},{"v":0.652906325217091,"d":"0.65"},1,"down","no"]
["ENSG00000152503","TRIM36","ENST00000513154;ENST00000379617;ENST00000515104;ENST00000379618","GO:0005737(cytoplasm);GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0016740(transferase activity);GO:0005622(intracellular);GO:0004842(ubiquitin-protein transferase activity);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0031410(cytoplasmic vesicle);GO:0051726(regulation of cell cycle);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0000209(protein polyubiquitination);GO:0001669(acrosomal vesicle);GO:0007340(acrosome reaction);GO:0016567(protein ubiquitination);GO:0016567(protein ubiquitination)","NA","NA","NA","tripartite motif containing 36 [Source:HGNC Symbol;Acc:HGNC:16280]",{"v":0.192361671519712,"d":"0.19"},{"v":0.158473427122526,"d":"0.16"},{"v":1.21384180939676,"d":"1.21"},{"v":0.279580418571113,"d":"0.28"},{"v":0.654061872402928,"d":"0.65"},1,"up","no"]
["MSTRG.13948","CICP14","ENST00000629111","NA","NA","NA","NA","capicua transcriptional repressor pseudogene 14 [Source:HGNC Symbol;Acc:HGNC:38542]",{"v":1.274961,"d":"1.27"},{"v":1.056111,"d":"1.06"},{"v":1.20722253626749,"d":"1.21"},{"v":0.271691643265073,"d":"0.27"},{"v":0.656076445227467,"d":"0.66"},1,"up","no"]
["MSTRG.6530","WSB1","ENST00000262394;ENST00000467843;ENST00000581185;ENST00000427287;ENST00000487603;ENST00000579733;ENST00000582208;ENST00000584114;ENST00000583786;ENST00000578312;ENST00000584354;ENST00000583193;ENST00000581440;ENST00000348811;ENST00000581089;ENST00000583096","GO:0005622(intracellular);GO:0016567(protein ubiquitination);GO:0035556(intracellular signal transduction);GO:0005515(protein binding);GO:0008150(biological_process);GO:0005829(cytosol);GO:0000209(protein polyubiquitination);GO:0043687(post-translational protein modification);GO:0004842(ubiquitin-protein transferase activity);GO:0004842(ubiquitin-protein transferase activity)","NA","NA","NA","WD repeat and SOCS box containing 1 [Source:HGNC Symbol;Acc:HGNC:19221]",{"v":5.06823264636131,"d":"5.07"},{"v":6.31903645698675,"d":"6.32"},{"v":0.802057826515233,"d":"0.80"},{"v":-0.318221839479892,"d":"-0.32"},{"v":0.656675803137596,"d":"0.66"},1,"down","no"]
["MSTRG.488","ELOVL1","ENST00000372458;ENST00000497050;ENST00000478481;ENST00000468865;ENST00000464204;ENST00000487209;ENST00000482302;ENST00000465321;ENST00000621943;ENST00000496932;ENST00000479439;ENST00000497569;ENST00000470769","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016740(transferase activity);GO:0006629(lipid metabolic process);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0009922(fatty acid elongase activity);GO:0102336(3-oxo-arachidoyl-CoA synthase activity);GO:0102337(3-oxo-cerotoyl-CoA synthase activity);GO:0102338(3-oxo-lignoceronyl-CoA synthase activity);GO:0006631(fatty acid metabolic process);GO:0006633(fatty acid biosynthetic process);GO:0019367(fatty acid elongation, saturated fatty acid);GO:0042761(very long-chain fatty acid biosynthetic process);GO:0034625(fatty acid elongation, monounsaturated fatty acid);GO:0005515(protein binding);GO:0035338(long-chain fatty-acyl-CoA biosynthetic process);GO:0030176(integral component of endoplasmic reticulum membrane);GO:0036109(alpha-linolenic acid metabolic process);GO:0030148(sphingolipid biosynthetic process);GO:0043651(linoleic acid metabolic process);GO:0034626(fatty acid elongation, polyunsaturated fatty acid);GO:0034626(fatty acid elongation, polyunsaturated fatty acid)","00062(Fatty acid elongation);00062(Fatty acid elongation)","K10247","EC:2.3.1.199","ELOVL fatty acid elongase 1 [Source:HGNC Symbol;Acc:HGNC:14418]",{"v":11.9014889329876,"d":"11.90"},{"v":14.8217768101316,"d":"14.82"},{"v":0.802973158039473,"d":"0.80"},{"v":-0.316576333060815,"d":"-0.32"},{"v":0.659123295053357,"d":"0.66"},1,"down","no"]
["MSTRG.13643","UPP1","ENST00000444999;ENST00000395560;ENST00000395564;ENST00000436673;ENST00000417464;ENST00000482015;ENST00000416681;ENST00000331803;ENST00000421046;ENST00000495446","GO:0009116(nucleoside metabolic process);GO:0003824(catalytic activity);GO:0016763(transferase activity, transferring pentosyl groups);GO:0005737(cytoplasm);GO:0016740(transferase activity);GO:0016757(transferase activity, transferring glycosyl groups);GO:0044206(UMP salvage);GO:0004850(uridine phosphorylase activity);GO:0009166(nucleotide catabolic process);GO:0005829(cytosol);GO:0006139(nucleobase-containing compound metabolic process);GO:0043097(pyrimidine nucleoside salvage);GO:0046135(pyrimidine nucleoside catabolic process);GO:0006218(uridine catabolic process);GO:0006220(pyrimidine nucleotide metabolic process);GO:0042149(cellular response to glucose starvation);GO:0046108(uridine metabolic process);GO:0046108(uridine metabolic process)","00240(Pyrimidine metabolism);00983(Drug metabolism - other enzymes);00983(Drug metabolism - other enzymes)","K00757","EC:2.4.2.3","uridine phosphorylase 1 [Source:HGNC Symbol;Acc:HGNC:12576]",{"v":2.20677734345641,"d":"2.21"},{"v":2.75362327725584,"d":"2.75"},{"v":0.801408588343865,"d":"0.80"},{"v":-0.319390124306682,"d":"-0.32"},{"v":0.659458250200941,"d":"0.66"},1,"down","no"]
["MSTRG.9536","CSNK2A1","ENST00000609606;ENST00000349736;ENST00000460062;ENST00000217244;ENST00000619801;ENST00000400217;ENST00000608066;ENST00000400227;ENST00000608490","GO:0005634(nucleus);GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0005654(nucleoplasm);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0005515(protein binding);GO:0007049(cell cycle);GO:0048511(rhythmic process);GO:0006915(apoptotic process);GO:0016055(Wnt signaling pathway);GO:0005829(cytosol);GO:0006457(protein folding);GO:0008284(positive regulation of cell proliferation);GO:0005886(plasma membrane);GO:0047485(protein N-terminus binding);GO:0007165(signal transduction);GO:0031519(PcG protein complex);GO:1901796(regulation of signal transduction by p53 class mediator);GO:0030307(positive regulation of cell growth);GO:0043154(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process);GO:0061077(chaperone-mediated protein folding);GO:0016236(macroautophagy);GO:0051879(Hsp90 protein binding);GO:0016580(Sin3 complex);GO:0045732(positive regulation of protein catabolic process);GO:0030177(positive regulation of Wnt signaling pathway);GO:0016581(NuRD complex);GO:0006656(phosphatidylcholine biosynthetic process);GO:0071174(mitotic spindle checkpoint);GO:0018107(peptidyl-threonine phosphorylation);GO:0005956(protein kinase CK2 complex);GO:0008013(beta-catenin binding);GO:0019888(protein phosphatase regulator activity);GO:0043021(ribonucleoprotein complex binding);GO:0021987(cerebral cortex development);GO:0033574(response to testosterone);GO:0046777(protein autophosphorylation);GO:0097421(liver regeneration);GO:1903076(regulation of protein localization to plasma membrane);GO:0000785(chromatin);GO:0005737(cytoplasm);GO:0005737(cytoplasm)","03008(Ribosome biogenesis in eukaryotes);04310(Wnt signaling pathway);04064(NF-kappa B signaling pathway);04137(Mitophagy - animal);04520(Adherens junction);05162(Measles);05168(Herpes simplex infection);05169(Epstein-Barr virus infection);05169(Epstein-Barr virus infection)","K03097","EC:2.7.11.1","casein kinase 2 alpha 1 [Source:HGNC Symbol;Acc:HGNC:2457]",{"v":6.98624918852323,"d":"6.99"},{"v":5.82960357664958,"d":"5.83"},{"v":1.19840896497775,"d":"1.20"},{"v":0.261120321366385,"d":"0.26"},{"v":0.661189997856981,"d":"0.66"},1,"up","no"]
["MSTRG.8622","HEATR5B","ENST00000233099;ENST00000467978;ENST00000478810;ENST00000425467;ENST00000471051","GO:0016020(membrane);GO:0070062(extracellular exosome);GO:0070062(extracellular exosome)","NA","NA","NA","HEAT repeat containing 5B [Source:HGNC Symbol;Acc:HGNC:29273]",{"v":3.65784824031197,"d":"3.66"},{"v":3.05341873568121,"d":"3.05"},{"v":1.19795172459237,"d":"1.20"},{"v":0.260569771153007,"d":"0.26"},{"v":0.662288421930881,"d":"0.66"},1,"up","no"]
["MSTRG.15073","MED22","ENST00000610888;ENST00000343730;ENST00000482295;ENST00000457204;ENST00000610672","GO:0005634(nucleus);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0001104(RNA polymerase II transcription cofactor activity);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0016592(mediator complex);GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0005737(cytoplasm)","NA","NA","NA","mediator complex subunit 22 [Source:HGNC Symbol;Acc:HGNC:11477]",{"v":3.14130698629568,"d":"3.14"},{"v":2.62102862403101,"d":"2.62"},{"v":1.19850159494424,"d":"1.20"},{"v":0.261231828900787,"d":"0.26"},{"v":0.662792708866567,"d":"0.66"},1,"up","no"]
["MSTRG.4908","SNRPN;SNHG14;AC124312.1;SNURF","ENST00000554227;ENST00000346403;ENST00000640631;ENST00000551938;ENST00000547292;ENST00000551361;ENST00000452731;ENST00000551312;ENST00000549804;ENST00000553108;ENST00000338327;ENST00000424208;ENST00000584968;ENST00000553597;ENST00000390687;ENST00000557108;ENST00000453082;ENST00000577565;ENST00000447911;ENST00000551631;ENST00000580062;ENST00000546682;ENST00000577949;ENST00000579070;ENST00000626200","GO:0003723(RNA binding);GO:0008380(RNA splicing);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0019013(viral nucleocapsid);GO:0030529(intracellular ribonucleoprotein complex);GO:0005681(spliceosomal complex);GO:0005737(cytoplasm);GO:0005515(protein binding);GO:0000398(mRNA splicing, via spliceosome);GO:0005682(U5 snRNP);GO:0046540(U4/U6 x U5 tri-snRNP complex);GO:0071013(catalytic step 2 spliceosome);GO:0005686(U2 snRNP);GO:0005685(U1 snRNP);GO:0071004(U2-type prespliceosome);GO:0030532(small nuclear ribonucleoprotein complex);GO:0009725(response to hormone);GO:0005687(U4 snRNP);GO:0016607(nuclear speck);GO:0003674(molecular_function);GO:0008150(biological_process);GO:0005687(U4 snRNP)","NA","NA","NA","small nuclear ribonucleoprotein polypeptide N [Source:HGNC Symbol;Acc:HGNC:11164];small nucleolar RNA host gene 14 [Source:HGNC Symbol;Acc:HGNC:37462];SNRPN upstream reading frame [Source:HGNC Symbol;Acc:HGNC:11171]",{"v":0.894368942975668,"d":"0.89"},{"v":0.746591724120884,"d":"0.75"},{"v":1.19793578482107,"d":"1.20"},{"v":0.260550574735045,"d":"0.26"},{"v":0.66397492507248,"d":"0.66"},1,"up","no"]
["MSTRG.9574","MAVS","ENST00000416600;ENST00000428216","GO:0051091(positive regulation of sequence-specific DNA binding transcription factor activity);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0001934(positive regulation of protein phosphorylation);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005739(mitochondrion);GO:0004871(signal transducer activity);GO:0005515(protein binding);GO:0007165(signal transduction);GO:0005741(mitochondrial outer membrane);GO:0051607(defense response to virus);GO:0002376(immune system process);GO:0045087(innate immune response);GO:0005777(peroxisome);GO:0005778(peroxisomal membrane);GO:0042742(defense response to bacterium);GO:0031966(mitochondrial membrane);GO:0016579(protein deubiquitination);GO:0045071(negative regulation of viral genome replication);GO:0016032(viral process);GO:0043123(positive regulation of I-kappaB kinase/NF-kappaB signaling);GO:1904469(positive regulation of tumor necrosis factor secretion);GO:2000778(positive regulation of interleukin-6 secretion);GO:0032727(positive regulation of interferon-alpha production);GO:0032728(positive regulation of interferon-beta production);GO:0032757(positive regulation of interleukin-8 production);GO:0032760(positive regulation of tumor necrosis factor production);GO:1900063(regulation of peroxisome organization);GO:0019901(protein kinase binding);GO:0002230(positive regulation of defense response to virus by host);GO:0032480(negative regulation of type I interferon production);GO:0071360(cellular response to exogenous dsRNA);GO:0033160(positive regulation of protein import into nucleus, translocation);GO:0035549(positive regulation of interferon-beta secretion);GO:0042993(positive regulation of transcription factor import into nucleus);GO:0060760(positive regulation of response to cytokine stimulus);GO:1902741(positive regulation of interferon-alpha secretion);GO:0060340(positive regulation of type I interferon-mediated signaling pathway);GO:0050700(CARD domain binding);GO:0002218(activation of innate immune response);GO:0032481(positive regulation of type I interferon production);GO:0039529(RIG-I signaling pathway);GO:0071651(positive regulation of chemokine (C-C motif) ligand 5 production);GO:0071660(positive regulation of IP-10 production);GO:0071660(positive regulation of IP-10 production)","04621(NOD-like receptor signaling pathway);04622(RIG-I-like receptor signaling pathway);04623(Cytosolic DNA-sensing pathway);05162(Measles);05164(Influenza A);05161(Hepatitis B);05160(Hepatitis C);05168(Herpes simplex infection);05168(Herpes simplex infection)","K12648","NA","mitochondrial antiviral signaling protein [Source:HGNC Symbol;Acc:HGNC:29233]",{"v":3.36831083731204,"d":"3.37"},{"v":4.1794222185031,"d":"4.18"},{"v":0.805927389293162,"d":"0.81"},{"v":-0.311278231103758,"d":"-0.31"},{"v":0.664455073845455,"d":"0.66"},1,"down","no"]
["MSTRG.13793","AC004922.1;ARPC1B;ARPC1A","MSTRG.13793.13;ENST00000638617;MSTRG.13793.11;ENST00000491294;MSTRG.13793.10;ENST00000252725;ENST00000262942;ENST00000474880;MSTRG.13793.12;ENST00000484600;ENST00000481997;ENST00000471960;MSTRG.13793.18;ENST00000468337;ENST00000451682;ENST00000484375;ENST00000441989;ENST00000458033;ENST00000493403;ENST00000443222;MSTRG.13793.14;ENST00000418347;ENST00000477240;ENST00000432343;ENST00000427217;ENST00000429246;ENST00000431816;ENST00000455009;ENST00000417330","GO:0015629(actin cytoskeleton);GO:0030833(regulation of actin filament polymerization);GO:0034314(Arp2/3 complex-mediated actin nucleation);GO:0005885(Arp2/3 protein complex);GO:0005737(cytoplasm);GO:0003779(actin binding);GO:0005856(cytoskeleton);GO:0005925(focal adhesion);GO:0038096(Fc-gamma receptor signaling pathway involved in phagocytosis);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0005200(structural constituent of cytoskeleton);GO:0006928(movement of cell or subcellular component);GO:0048013(ephrin receptor signaling pathway);GO:0051015(actin filament binding);GO:0032403(protein complex binding);GO:0032355(response to estradiol);GO:0043627(response to estrogen);GO:0036284(tubulobulbar complex);GO:0061024(membrane organization);GO:0030036(actin cytoskeleton organization);GO:0036195(muscle cell projection membrane);GO:0036284(tubulobulbar complex)","04144(Endocytosis);04810(Regulation of actin cytoskeleton);04666(Fc gamma R-mediated phagocytosis);05130(Pathogenic Escherichia coli infection);05132(Salmonella infection);05131(Shigellosis);05100(Bacterial invasion of epithelial cells);05100(Bacterial invasion of epithelial cells)","K05757","NA","actin related protein 2/3 complex subunit 1B [Source:HGNC Symbol;Acc:HGNC:704];actin related protein 2/3 complex subunit 1A [Source:HGNC Symbol;Acc:HGNC:703]",{"v":35.9338421362333,"d":"35.93"},{"v":44.520305236297,"d":"44.52"},{"v":0.807133777396853,"d":"0.81"},{"v":-0.309120283847917,"d":"-0.31"},{"v":0.66586379134211,"d":"0.67"},1,"down","no"]
["MSTRG.15422","NDUFA1","ENST00000371437","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005829(cytosol);GO:0055114(oxidation-reduction process);GO:0005739(mitochondrion);GO:0005743(mitochondrial inner membrane);GO:0070469(respiratory chain);GO:0031966(mitochondrial membrane);GO:0032981(mitochondrial respiratory chain complex I assembly);GO:0008137(NADH dehydrogenase (ubiquinone) activity);GO:0006120(mitochondrial electron transport, NADH to ubiquinone);GO:0005747(mitochondrial respiratory chain complex I)","00190(Oxidative phosphorylation);04723(Retrograde endocannabinoid signaling);05010(Alzheimer's disease);05012(Parkinson's disease);05016(Huntington's disease);04932(Non-alcoholic fatty liver disease (NAFLD))","K03945","NA","NADH:ubiquinone oxidoreductase subunit A1 [Source:HGNC Symbol;Acc:HGNC:7683]",{"v":29.307095,"d":"29.31"},{"v":36.311153,"d":"36.31"},{"v":0.807110008321686,"d":"0.81"},{"v":-0.309162770028972,"d":"-0.31"},{"v":0.666697586013898,"d":"0.67"},1,"down","no"]
["MSTRG.5421","NGRN;AC091167.7;GDPGP1;GOLGA2P8;AC091167.3;AC091167.8;TTLL13P","ENST00000379095;ENST00000331497;ENST00000622269;ENST00000558017;ENST00000411845;ENST00000505201;ENST00000559204;ENST00000561573;ENST00000641334;ENST00000641199;ENST00000617037;ENST00000558291;ENST00000561433","GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005576(extracellular region);GO:0007275(multicellular organism development);GO:0007399(nervous system development);GO:0030154(cell differentiation);GO:0030182(neuron differentiation);GO:0005737(cytoplasm);GO:0000166(nucleotide binding);GO:0016740(transferase activity);GO:0016787(hydrolase activity);GO:0043547(positive regulation of GTPase activity);GO:0016779(nucleotidyltransferase activity);GO:0080048(GDP-D-glucose phosphorylase activity);GO:0005085(guanyl-nucleotide exchange factor activity);GO:0006006(glucose metabolic process);GO:0006464(cellular protein modification process);GO:0005524(ATP binding);GO:0016874(ligase activity);GO:0005874(microtubule);GO:0005829(cytosol);GO:0070740(tubulin-glutamic acid ligase activity);GO:0018095(protein polyglutamylation);GO:0006006(glucose metabolic process)","NA","NA","NA","neugrin, neurite outgrowth associated [Source:HGNC Symbol;Acc:HGNC:18077];GDP-D-glucose phosphorylase 1 [Source:HGNC Symbol;Acc:HGNC:34360];golgin A2 pseudogene 8 [Source:HGNC Symbol;Acc:HGNC:49922];tubulin tyrosine ligase like 13, pseudogene [Source:HGNC Symbol;Acc:HGNC:32484]",{"v":2.0787876393451,"d":"2.08"},{"v":1.74110531407942,"d":"1.74"},{"v":1.19394709931388,"d":"1.19"},{"v":0.25573891595928,"d":"0.26"},{"v":0.667928711197954,"d":"0.67"},1,"up","no"]
["ENSG00000104970","KIR3DX1","ENST00000610811;ENST00000613375;ENST00000446586;ENST00000611588","GO:0005576(extracellular region);GO:0005576(extracellular region)","NA","NA","NA","killer cell immunoglobulin like receptor, three Ig domains X1 [Source:HGNC Symbol;Acc:HGNC:25043]",{"v":0.17371746497561,"d":"0.17"},{"v":0.140548237073171,"d":"0.14"},{"v":1.23599888972759,"d":"1.24"},{"v":0.305677447299558,"d":"0.31"},{"v":0.668342330370542,"d":"0.67"},1,"up","no"]
["MSTRG.12747","BTN3A1","ENST00000425234;ENST00000502361;MSTRG.12747.7;ENST00000414912;ENST00000289361;ENST00000082468;ENST00000465690;ENST00000506698;MSTRG.12747.3;ENST00000476549;ENST00000513047;ENST00000450085","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0002376(immune system process);GO:0002250(adaptive immune response);GO:0050663(cytokine secretion);GO:0050852(T cell receptor signaling pathway);GO:0050798(activated T cell proliferation);GO:0072643(interferon-gamma secretion);GO:0072643(interferon-gamma secretion)","NA","NA","NA","butyrophilin subfamily 3 member A1 [Source:HGNC Symbol;Acc:HGNC:1138]",{"v":19.6417997181577,"d":"19.64"},{"v":16.4837802738707,"d":"16.48"},{"v":1.19158344698958,"d":"1.19"},{"v":0.252879987484979,"d":"0.25"},{"v":0.669389731283488,"d":"0.67"},1,"up","no"]
["MSTRG.4360","DHRS1","ENST00000288111;ENST00000559483;ENST00000561137;ENST00000558340;ENST00000561281;ENST00000558114;ENST00000560991;ENST00000559084;ENST00000396813;ENST00000561273;ENST00000559088","GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0005515(protein binding);GO:0005783(endoplasmic reticulum);GO:0005739(mitochondrion);GO:0005743(mitochondrial inner membrane);GO:0005743(mitochondrial inner membrane)","NA","NA","NA","dehydrogenase/reductase 1 [Source:HGNC Symbol;Acc:HGNC:16445]",{"v":0.842711048780488,"d":"0.84"},{"v":1.05357530747701,"d":"1.05"},{"v":0.799858389618605,"d":"0.80"},{"v":-0.322183493236161,"d":"-0.32"},{"v":0.670795475543886,"d":"0.67"},1,"down","no"]
["MSTRG.8007","UPF1","ENST00000596842;ENST00000262803;ENST00000599848;ENST00000601689;ENST00000598471;ENST00000600012;ENST00000600868;ENST00000594504;ENST00000594243;ENST00000600689;ENST00000600310;ENST00000598209","GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0005654(nucleoplasm);GO:0016787(hydrolase activity);GO:0003677(DNA binding);GO:0004386(helicase activity);GO:0000184(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay);GO:0005515(protein binding);GO:0000932(P-body);GO:0000956(nuclear-transcribed mRNA catabolic process);GO:0005829(cytosol);GO:0071222(cellular response to lipopolysaccharide);GO:0061158(3'-UTR-mediated mRNA destabilization);GO:0000784(nuclear chromosome, telomeric region);GO:0071347(cellular response to interleukin-1);GO:0061014(positive regulation of mRNA catabolic process);GO:0035145(exon-exon junction complex);GO:0004004(ATP-dependent RNA helicase activity);GO:0071044(histone mRNA catabolic process);GO:0042162(telomeric DNA binding);GO:0032204(regulation of telomere maintenance);GO:0044770(cell cycle phase transition);GO:0044530(supraspliceosomal complex);GO:0006260(DNA replication);GO:0000294(nuclear-transcribed mRNA catabolic process, endonucleolytic cleavage-dependent decay);GO:0006406(mRNA export from nucleus);GO:0006449(regulation of translational termination);GO:0000785(chromatin);GO:0003682(chromatin binding);GO:0006281(DNA repair);GO:0032201(telomere maintenance via semi-conservative replication);GO:0009048(dosage compensation by inactivation of X chromosome);GO:0009048(dosage compensation by inactivation of X chromosome)","03013(RNA transport);03015(mRNA surveillance pathway);03015(mRNA surveillance pathway)","K14326","EC:3.6.4.-","UPF1, RNA helicase and ATPase [Source:HGNC Symbol;Acc:HGNC:9962]",{"v":9.78218738662791,"d":"9.78"},{"v":12.0783632618605,"d":"12.08"},{"v":0.809893457792981,"d":"0.81"},{"v":-0.304195962227723,"d":"-0.30"},{"v":0.671012043321522,"d":"0.67"},1,"down","no"]
["ENSG00000138182","KIF20B","ENST00000371728;ENST00000260753;ENST00000478929","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0051301(cell division);GO:0042803(protein homodimerization activity);GO:0003777(microtubule motor activity);GO:0005856(cytoskeleton);GO:0042995(cell projection);GO:0007049(cell cycle);GO:0008017(microtubule binding);GO:0048471(perinuclear region of cytoplasm);GO:0030496(midbody);GO:0005874(microtubule);GO:0007018(microtubule-based movement);GO:0005730(nucleolus);GO:0000922(spindle pole);GO:0005813(centrosome);GO:0005815(microtubule organizing center);GO:0005819(spindle);GO:0007088(regulation of mitotic nuclear division);GO:0005515(protein binding);GO:0030424(axon);GO:0048812(neuron projection morphogenesis);GO:2000114(regulation of establishment of cell polarity);GO:2001224(positive regulation of neuron migration);GO:0030426(growth cone);GO:0007050(cell cycle arrest);GO:0016887(ATPase activity);GO:0051233(spindle midzone);GO:0008284(positive regulation of cell proliferation);GO:0005871(kinesin complex);GO:0097431(mitotic spindle pole);GO:1990023(mitotic spindle midzone);GO:0032467(positive regulation of cytokinesis);GO:0090316(positive regulation of intracellular protein transport);GO:0035372(protein localization to microtubule);GO:0070938(contractile ring);GO:1903438(positive regulation of mitotic cytokinetic process);GO:0050699(WW domain binding);GO:0008574(ATP-dependent microtubule motor activity, plus-end-directed);GO:0001843(neural tube closure);GO:0070201(regulation of establishment of protein localization);GO:2001222(regulation of neuron migration);GO:0015630(microtubule cytoskeleton);GO:0003774(motor activity);GO:0003774(motor activity)","NA","NA","NA","kinesin family member 20B [Source:HGNC Symbol;Acc:HGNC:7212]",{"v":0.914717009487666,"d":"0.91"},{"v":0.76601034841629,"d":"0.77"},{"v":1.19413139963295,"d":"1.19"},{"v":0.255961596375357,"d":"0.26"},{"v":0.672343972324812,"d":"0.67"},1,"up","no"]
["MSTRG.8991","UNC50","ENST00000357765;ENST00000409975;ENST00000466492;ENST00000393493;ENST00000423713","GO:0003723(RNA binding);GO:0006810(transport);GO:0005634(nucleus);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0015031(protein transport);GO:0005794(Golgi apparatus);GO:0000139(Golgi membrane);GO:0005637(nuclear inner membrane);GO:0030173(integral component of Golgi membrane);GO:0007166(cell surface receptor signaling pathway);GO:0007166(cell surface receptor signaling pathway)","NA","NA","NA","unc-50 inner nuclear membrane RNA binding protein [Source:HGNC Symbol;Acc:HGNC:16046]",{"v":3.0649903470852,"d":"3.06"},{"v":3.81082610672646,"d":"3.81"},{"v":0.804285018850692,"d":"0.80"},{"v":-0.31422124719573,"d":"-0.31"},{"v":0.672830514131737,"d":"0.67"},1,"down","no"]
["MSTRG.8324","PRMT1;ADM5","ENST00000529284;ENST00000527412;ENST00000524771;ENST00000420022;ENST00000525616;ENST00000526224;ENST00000529836;ENST00000527866;ENST00000529650;ENST00000534676;ENST00000530361;ENST00000528126;ENST00000391851;ENST00000534280;ENST00000530070;MSTRG.8324.5;ENST00000525915;ENST00000454376;ENST00000528623","GO:0008168(methyltransferase activity);GO:0016740(transferase activity);GO:0032259(methylation);GO:0006479(protein methylation);GO:0045648(positive regulation of erythrocyte differentiation);GO:1900745(positive regulation of p38MAPK cascade);GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005515(protein binding);GO:0005654(nucleoplasm);GO:0042802(identical protein binding);GO:0006355(regulation of transcription, DNA-templated);GO:0006977(DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest);GO:0008284(positive regulation of cell proliferation);GO:0019899(enzyme binding);GO:0007166(cell surface receptor signaling pathway);GO:0031175(neuron projection development);GO:0045652(regulation of megakaryocyte differentiation);GO:0008327(methyl-CpG binding);GO:0016274(protein-arginine N-methyltransferase activity);GO:0044020(histone methyltransferase activity (H4-R3 specific));GO:0018216(peptidyl-arginine methylation);GO:0043985(histone H4-R3 methylation);GO:0034709(methylosome);GO:0042054(histone methyltransferase activity);GO:0046985(positive regulation of hemoglobin biosynthetic process);GO:0019919(peptidyl-arginine methylation, to asymmetrical-dimethyl arginine);GO:0035246(peptidyl-arginine N-methylation);GO:0048273(mitogen-activated protein kinase p38 binding);GO:0045653(negative regulation of megakaryocyte differentiation);GO:0016571(histone methylation);GO:0008276(protein methyltransferase activity);GO:0035242(protein-arginine omega-N asymmetric methyltransferase activity);GO:0008170(N-methyltransferase activity);GO:0001701(in utero embryonic development);GO:0005576(extracellular region);GO:0003674(molecular_function);GO:0008150(biological_process);GO:0005575(cellular_component);GO:0001701(in utero embryonic development)","04068(FoxO signaling pathway);04922(Glucagon signaling pathway);04922(Glucagon signaling pathway)","K11434","EC:2.1.1.319","protein arginine methyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:5187];adrenomedullin 5 (putative) [Source:HGNC Symbol;Acc:HGNC:27293]",{"v":4.9529578812682,"d":"4.95"},{"v":4.16220234778389,"d":"4.16"},{"v":1.18998488478229,"d":"1.19"},{"v":0.250943248501183,"d":"0.25"},{"v":0.674336868892532,"d":"0.67"},1,"up","no"]
["MSTRG.15333","SPIN3","ENST00000374919;ENST00000639791;ENST00000638664;ENST00000639482;ENST00000639888;ENST00000638289;ENST00000640101;ENST00000638386;ENST00000639583","GO:0007276(gamete generation);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016021(integral component of membrane)","NA","NA","NA","spindlin family member 3 [Source:HGNC Symbol;Acc:HGNC:27272]",{"v":0.270473440691876,"d":"0.27"},{"v":0.227394368916104,"d":"0.23"},{"v":1.18944651963508,"d":"1.19"},{"v":0.250290406196187,"d":"0.25"},{"v":0.67537987851459,"d":"0.68"},1,"up","no"]
["MSTRG.15393","TCEAL8","ENST00000360000;ENST00000372685","GO:0005634(nucleus);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0050699(WW domain binding);GO:0050699(WW domain binding)","NA","NA","NA","transcription elongation factor A like 8 [Source:HGNC Symbol;Acc:HGNC:28683]",{"v":8.35170918085106,"d":"8.35"},{"v":7.02054982978723,"d":"7.02"},{"v":1.18960898837523,"d":"1.19"},{"v":0.250487453171578,"d":"0.25"},{"v":0.675491492909501,"d":"0.68"},1,"up","no"]
["MSTRG.14035","GSTK1","ENST00000358406;ENST00000479303;ENST00000494735;ENST00000489654;ENST00000436038;ENST00000473649;ENST00000442394;ENST00000443571;ENST00000409500","GO:0055114(oxidation-reduction process);GO:0005777(peroxisome);GO:0015035(protein disulfide oxidoreductase activity);GO:0016020(membrane);GO:0016740(transferase activity);GO:0005515(protein binding);GO:0098869(cellular oxidant detoxification);GO:0004364(glutathione transferase activity);GO:0070062(extracellular exosome);GO:0005759(mitochondrial matrix);GO:0005102(receptor binding);GO:0030855(epithelial cell differentiation);GO:1901687(glutathione derivative biosynthetic process);GO:0005622(intracellular);GO:0004602(glutathione peroxidase activity);GO:0006749(glutathione metabolic process);GO:0005739(mitochondrion);GO:0005743(mitochondrial inner membrane);GO:0005743(mitochondrial inner membrane)","00480(Glutathione metabolism);00980(Metabolism of xenobiotics by cytochrome P450);00982(Drug metabolism - cytochrome P450);04146(Peroxisome);05204(Chemical carcinogenesis);05204(Chemical carcinogenesis)","K13299","EC:2.5.1.18","glutathione S-transferase kappa 1 [Source:HGNC Symbol;Acc:HGNC:16906]",{"v":17.5727722055345,"d":"17.57"},{"v":14.8042169824976,"d":"14.80"},{"v":1.18701125674597,"d":"1.19"},{"v":0.247333616508532,"d":"0.25"},{"v":0.676366168327533,"d":"0.68"},1,"up","no"]
["MSTRG.7933","SIN3B","ENST00000379803;ENST00000595541;ENST00000596802;ENST00000599880;ENST00000248054;ENST00000602204;ENST00000596638;ENST00000594372;ENST00000601141;ENST00000595049;ENST00000595900","GO:0005634(nucleus);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0005515(protein binding);GO:0005654(nucleoplasm);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0019216(regulation of lipid metabolic process);GO:0016575(histone deacetylation);GO:0004407(histone deacetylase activity);GO:0001106(RNA polymerase II transcription corepressor activity);GO:0016580(Sin3 complex);GO:0003682(chromatin binding);GO:0003714(transcription corepressor activity);GO:0045892(negative regulation of transcription, DNA-templated);GO:0000805(X chromosome);GO:0000806(Y chromosome);GO:0001741(XY body);GO:0005737(cytoplasm);GO:0030849(autosome);GO:0030849(autosome)","NA","NA","NA","SIN3 transcription regulator family member B [Source:HGNC Symbol;Acc:HGNC:19354]",{"v":2.86539849333485,"d":"2.87"},{"v":2.41523900045574,"d":"2.42"},{"v":1.18638300093455,"d":"1.19"},{"v":0.246569831425816,"d":"0.25"},{"v":0.676882143237154,"d":"0.68"},1,"up","no"]
["MSTRG.5284","COX5A","ENST00000322347;ENST00000562233;ENST00000567270;ENST00000564811;ENST00000568783;ENST00000568517","GO:0016020(membrane);GO:0046872(metal ion binding);GO:0005743(mitochondrial inner membrane);GO:0005739(mitochondrion);GO:0005515(protein binding);GO:1902600(hydrogen ion transmembrane transport);GO:0004129(cytochrome-c oxidase activity);GO:0070062(extracellular exosome);GO:0006123(mitochondrial electron transport, cytochrome c to oxygen);GO:0009055(electron carrier activity);GO:0005751(mitochondrial respiratory chain complex IV);GO:0043209(myelin sheath);GO:0043209(myelin sheath)","00190(Oxidative phosphorylation);04260(Cardiac muscle contraction);05010(Alzheimer's disease);05012(Parkinson's disease);05016(Huntington's disease);04932(Non-alcoholic fatty liver disease (NAFLD));04932(Non-alcoholic fatty liver disease (NAFLD))","K02264","NA","cytochrome c oxidase subunit 5A [Source:HGNC Symbol;Acc:HGNC:2267]",{"v":9.27596842593905,"d":"9.28"},{"v":11.4134301091425,"d":"11.41"},{"v":0.812723987200721,"d":"0.81"},{"v":-0.299162619471085,"d":"-0.30"},{"v":0.678003664722847,"d":"0.68"},1,"down","no"]
["ENSG00000197355","UAP1L1","ENST00000474787;ENST00000360271;ENST00000409858;ENST00000476184","GO:0016740(transferase activity);GO:0008152(metabolic process);GO:0016779(nucleotidyltransferase activity);GO:0070569(uridylyltransferase activity);GO:0005829(cytosol);GO:0003977(UDP-N-acetylglucosamine diphosphorylase activity);GO:0006048(UDP-N-acetylglucosamine biosynthetic process);GO:0006048(UDP-N-acetylglucosamine biosynthetic process)","00520(Amino sugar and nucleotide sugar metabolism);00520(Amino sugar and nucleotide sugar metabolism)","K00972","EC:2.7.7.23;EC:2.7.7.83","UDP-N-acetylglucosamine pyrophosphorylase 1 like 1 [Source:HGNC Symbol;Acc:HGNC:28082]",{"v":1.90645523622942,"d":"1.91"},{"v":2.34704479840999,"d":"2.35"},{"v":0.812279014665997,"d":"0.81"},{"v":-0.299952722239493,"d":"-0.30"},{"v":0.678373950890491,"d":"0.68"},1,"down","no"]
["MSTRG.10460","GTPBP1","ENST00000418601;ENST00000216044;ENST00000462332;ENST00000475959;ENST00000470836;ENST00000484971;ENST00000488787;ENST00000487538;ENST00000458073;ENST00000461428;ENST00000460605","GO:0003723(RNA binding);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005525(GTP binding);GO:0000166(nucleotide binding);GO:0003924(GTPase activity);GO:0005829(cytosol);GO:0006955(immune response);GO:0007165(signal transduction);GO:0046039(GTP metabolic process);GO:0061014(positive regulation of mRNA catabolic process);GO:0000177(cytoplasmic exosome (RNase complex));GO:0000177(cytoplasmic exosome (RNase complex))","NA","NA","NA","GTP binding protein 1 [Source:HGNC Symbol;Acc:HGNC:4669]",{"v":3.10594067340191,"d":"3.11"},{"v":3.82094924491795,"d":"3.82"},{"v":0.812871481486692,"d":"0.81"},{"v":-0.298900820912203,"d":"-0.30"},{"v":0.680237900068187,"d":"0.68"},1,"down","no"]
["MSTRG.14208","XPO7","ENST00000252512;ENST00000518808;ENST00000521303;ENST00000517551;ENST00000522015;ENST00000520754;ENST00000433566;ENST00000519769","GO:0006810(transport);GO:0051028(mRNA transport);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0006886(intracellular protein transport);GO:0015031(protein transport);GO:0005515(protein binding);GO:0008536(Ran GTPase binding);GO:0005643(nuclear pore);GO:0006611(protein export from nucleus);GO:0005049(nuclear export signal receptor activity);GO:0005622(intracellular);GO:0005622(intracellular)","NA","NA","NA","exportin 7 [Source:HGNC Symbol;Acc:HGNC:14108]",{"v":8.00940621276596,"d":"8.01"},{"v":9.83017850586192,"d":"9.83"},{"v":0.814777290970841,"d":"0.81"},{"v":-0.295522324034117,"d":"-0.30"},{"v":0.681666929839819,"d":"0.68"},1,"down","no"]
["MSTRG.15080","BRD3","ENST00000303407;ENST00000433041;ENST00000494743;ENST00000371834","GO:0005634(nucleus);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0016569(covalent chromatin modification);GO:0005515(protein binding);GO:0003682(chromatin binding);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0070577(lysine-acetylated histone binding);GO:0070577(lysine-acetylated histone binding)","NA","NA","NA","bromodomain containing 3 [Source:HGNC Symbol;Acc:HGNC:1104]",{"v":3.03793731573589,"d":"3.04"},{"v":3.73015077225131,"d":"3.73"},{"v":0.81442748597059,"d":"0.81"},{"v":-0.296141843389863,"d":"-0.30"},{"v":0.682063286573616,"d":"0.68"},1,"down","no"]
["MSTRG.7378","METRNL","ENST00000320095;ENST00000571940;ENST00000574053;ENST00000570778;ENST00000571814","GO:0005576(extracellular region);GO:0005615(extracellular space);GO:0005179(hormone activity);GO:0003674(molecular_function);GO:0070062(extracellular exosome);GO:0045444(fat cell differentiation);GO:0050728(negative regulation of inflammatory response);GO:0014850(response to muscle activity);GO:0050873(brown fat cell differentiation);GO:0009409(response to cold);GO:0090336(positive regulation of brown fat cell differentiation);GO:2000507(positive regulation of energy homeostasis);GO:2000507(positive regulation of energy homeostasis)","NA","NA","NA","meteorin like, glial cell differentiation regulator [Source:HGNC Symbol;Acc:HGNC:27584]",{"v":4.90272190517898,"d":"4.90"},{"v":6.01482459824829,"d":"6.01"},{"v":0.815106380094078,"d":"0.82"},{"v":-0.294939736134151,"d":"-0.29"},{"v":0.683608050747048,"d":"0.68"},1,"down","no"]
["ENSG00000176454","LPCAT4","ENST00000569804;ENST00000314891;ENST00000562431;ENST00000563748;ENST00000623384;ENST00000567507;ENST00000566581;ENST00000562404;ENST00000563240","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016740(transferase activity);GO:0016746(transferase activity, transferring acyl groups);GO:0006629(lipid metabolic process);GO:0008152(metabolic process);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0008654(phospholipid biosynthetic process);GO:0006654(phosphatidic acid biosynthetic process);GO:0003841(1-acylglycerol-3-phosphate O-acyltransferase activity);GO:0006644(phospholipid metabolic process);GO:0036148(phosphatidylglycerol acyl-chain remodeling);GO:0036150(phosphatidylserine acyl-chain remodeling);GO:0036151(phosphatidylcholine acyl-chain remodeling);GO:0036152(phosphatidylethanolamine acyl-chain remodeling);GO:0047144(2-acylglycerol-3-phosphate O-acyltransferase activity);GO:0047166(1-alkenylglycerophosphoethanolamine O-acyltransferase activity);GO:0047184(1-acylglycerophosphocholine O-acyltransferase activity);GO:0047192(1-alkylglycerophosphocholine O-acetyltransferase activity);GO:0071617(lysophospholipid acyltransferase activity);GO:0071617(lysophospholipid acyltransferase activity)","00564(Glycerophospholipid metabolism);00565(Ether lipid metabolism);00565(Ether lipid metabolism)","K13512","EC:2.3.1.23;EC:2.3.1.-","lysophosphatidylcholine acyltransferase 4 [Source:HGNC Symbol;Acc:HGNC:30059]",{"v":3.74588428360075,"d":"3.75"},{"v":3.17453553177745,"d":"3.17"},{"v":1.17997869171853,"d":"1.18"},{"v":0.238760807358669,"d":"0.24"},{"v":0.685479558061034,"d":"0.69"},1,"up","no"]
["ENSG00000096872","IFT74","ENST00000380062;ENST00000517444;ENST00000494236;ENST00000429045;ENST00000482986;ENST00000443698;ENST00000518614","GO:0042073(intraciliary transport);GO:0060271(cilium assembly);GO:0030992(intraciliary transport particle B);GO:0005929(cilium);GO:0048487(beta-tubulin binding);GO:0042995(cell projection);GO:0031410(cytoplasmic vesicle);GO:0005813(centrosome);GO:0035735(intraciliary transport involved in cilium assembly);GO:0097542(ciliary tip);GO:0030030(cell projection organization);GO:0031514(motile cilium);GO:0003682(chromatin binding);GO:0003334(keratinocyte development);GO:0007219(Notch signaling pathway);GO:0007368(determination of left/right symmetry);GO:0007507(heart development);GO:0008544(epidermis development);GO:0033630(positive regulation of cell adhesion mediated by integrin);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0050680(negative regulation of epithelial cell proliferation);GO:1905515(non-motile cilium assembly);GO:0005634(nucleus);GO:0005634(nucleus)","NA","NA","NA","intraflagellar transport 74 [Source:HGNC Symbol;Acc:HGNC:21424]",{"v":0.64786837816245,"d":"0.65"},{"v":0.545307124900133,"d":"0.55"},{"v":1.18807979683211,"d":"1.19"},{"v":0.248631737340528,"d":"0.25"},{"v":0.686557427022449,"d":"0.69"},1,"up","no"]
["ENSG00000156853","ZNF689","ENST00000287461","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0005622(intracellular);GO:0035914(skeletal muscle cell differentiation)","NA","NA","NA","zinc finger protein 689 [Source:HGNC Symbol;Acc:HGNC:25173]",{"v":3.12231177975475,"d":"3.12"},{"v":2.64583258355374,"d":"2.65"},{"v":1.180086676369,"d":"1.18"},{"v":0.238892828210247,"d":"0.24"},{"v":0.687704653542468,"d":"0.69"},1,"up","no"]
["MSTRG.14444","DECR1","ENST00000220764;ENST00000517597;ENST00000521668;ENST00000524332;ENST00000520859;ENST00000522583;ENST00000519328;ENST00000520148;ENST00000524326;ENST00000523447;ENST00000519410;ENST00000522161;ENST00000517301;ENST00000517761;ENST00000519007;ENST00000517314;ENST00000520227;ENST00000518725;ENST00000521603","GO:0005634(nucleus);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0005739(mitochondrion);GO:0006629(lipid metabolic process);GO:0006631(fatty acid metabolic process);GO:0070062(extracellular exosome);GO:0005759(mitochondrial matrix);GO:0051289(protein homotetramerization);GO:0006635(fatty acid beta-oxidation);GO:0070402(NADPH binding);GO:0008670(2,4-dienoyl-CoA reductase (NADPH) activity);GO:0016651(oxidoreductase activity, acting on NAD(P)H);GO:0016651(oxidoreductase activity, acting on NAD(P)H)","NA","NA","NA","2,4-dienoyl-CoA reductase 1 [Source:HGNC Symbol;Acc:HGNC:2753]",{"v":4.97829214057599,"d":"4.98"},{"v":6.10356951924722,"d":"6.10"},{"v":0.815636182217186,"d":"0.82"},{"v":-0.294002319106819,"d":"-0.29"},{"v":0.687893114097914,"d":"0.69"},1,"down","no"]
["ENSG00000121864","ZNF639","ENST00000621687;ENST00000326361;ENST00000483460;ENST00000491818;ENST00000496856;ENST00000484866;ENST00000481587;ENST00000466663;ENST00000466264","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0005654(nucleoplasm);GO:0006366(transcription from RNA polymerase II promoter);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0005515(protein binding);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0044212(transcription regulatory region DNA binding);GO:0045892(negative regulation of transcription, DNA-templated);GO:0046718(viral entry into host cell);GO:0030307(positive regulation of cell growth);GO:0001077(transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0043621(protein self-association);GO:0043922(negative regulation by host of viral transcription);GO:0043923(positive regulation by host of viral transcription);GO:0043923(positive regulation by host of viral transcription)","NA","NA","NA","zinc finger protein 639 [Source:HGNC Symbol;Acc:HGNC:30950]",{"v":0.496240672692812,"d":"0.50"},{"v":0.420177048986733,"d":"0.42"},{"v":1.18102755466894,"d":"1.18"},{"v":0.240042624786287,"d":"0.24"},{"v":0.690169886908999,"d":"0.69"},1,"up","no"]
["MSTRG.12699","DEK","MSTRG.12699.4;ENST00000397239;ENST00000507591;ENST00000244776;ENST00000515742;ENST00000503715;ENST00000512145;ENST00000515770;ENST00000505224","GO:0003723(RNA binding);GO:0005634(nucleus);GO:0016569(covalent chromatin modification);GO:0003677(DNA binding);GO:0003682(chromatin binding);GO:0005654(nucleoplasm);GO:0006338(chromatin remodeling);GO:0045815(positive regulation of gene expression, epigenetic);GO:0007165(signal transduction);GO:0042393(histone binding);GO:0006366(transcription from RNA polymerase II promoter);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0019079(viral genome replication);GO:2000779(regulation of double-strand break repair);GO:2001032(regulation of double-strand break repair via nonhomologous end joining);GO:0043292(contractile fiber);GO:0043292(contractile fiber)","NA","NA","NA","DEK proto-oncogene [Source:HGNC Symbol;Acc:HGNC:2768]",{"v":9.73544734533364,"d":"9.74"},{"v":11.8912465695941,"d":"11.89"},{"v":0.818707045418364,"d":"0.82"},{"v":-0.288580784327086,"d":"-0.29"},{"v":0.690461702855205,"d":"0.69"},1,"down","no"]
["ENSG00000173372","C1QA","ENST00000374642;ENST00000402322","GO:0005515(protein binding);GO:0005576(extracellular region);GO:0005581(collagen trimer);GO:0006508(proteolysis);GO:0002376(immune system process);GO:0045087(innate immune response);GO:0006958(complement activation, classical pathway);GO:0010039(response to iron ion);GO:0005615(extracellular space);GO:0004252(serine-type endopeptidase activity);GO:0006956(complement activation);GO:0030449(regulation of complement activation);GO:0070062(extracellular exosome);GO:0007267(cell-cell signaling);GO:0005602(complement component C1 complex);GO:0005602(complement component C1 complex)","04610(Complement and coagulation cascades);05322(Systemic lupus erythematosus);05020(Prion diseases);05133(Pertussis);05150(Staphylococcus aureus infection);05142(Chagas disease (American trypanosomiasis));05142(Chagas disease (American trypanosomiasis))","K03986","NA","complement C1q A chain [Source:HGNC Symbol;Acc:HGNC:1241]",{"v":0.923108186320755,"d":"0.92"},{"v":0.772114471698113,"d":"0.77"},{"v":1.19555871591237,"d":"1.20"},{"v":0.2576849849851,"d":"0.26"},{"v":0.691735996739654,"d":"0.69"},1,"up","no"]
["MSTRG.8737","MDH1","ENST00000233114;ENST00000436321;ENST00000409908;ENST00000495083;ENST00000454035;ENST00000472098;ENST00000442225;ENST00000484538;ENST00000485155;ENST00000409476;ENST00000462944;ENST00000539945;ENST00000432309;ENST00000485781","GO:0005737(cytoplasm);GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0006099(tricarboxylic acid cycle);GO:0003824(catalytic activity);GO:0005975(carbohydrate metabolic process);GO:0016616(oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor);GO:0005515(protein binding);GO:0005615(extracellular space);GO:0016615(malate dehydrogenase activity);GO:0030060(L-malate dehydrogenase activity);GO:0006108(malate metabolic process);GO:0019752(carboxylic acid metabolic process);GO:0005739(mitochondrion);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0006094(gluconeogenesis);GO:0004470(malic enzyme activity);GO:0047860(diiodophenylpyruvate reductase activity);GO:0006107(oxaloacetate metabolic process);GO:0006734(NADH metabolic process);GO:0051287(NAD binding);GO:0019674(NAD metabolic process);GO:0043209(myelin sheath);GO:0043209(myelin sheath)","00020(Citrate cycle (TCA cycle));00620(Pyruvate metabolism);00630(Glyoxylate and dicarboxylate metabolism);00270(Cysteine and methionine metabolism);04964(Proximal tubule bicarbonate reclamation);04964(Proximal tubule bicarbonate reclamation)","K00025","EC:1.1.1.37","malate dehydrogenase 1 [Source:HGNC Symbol;Acc:HGNC:6970]",{"v":1.96497280741483,"d":"1.96"},{"v":2.40402459539078,"d":"2.40"},{"v":0.817368013281669,"d":"0.82"},{"v":-0.290942308566782,"d":"-0.29"},{"v":0.693159849097364,"d":"0.69"},1,"down","no"]
["MSTRG.8194","DEDD2","ENST00000336034;ENST00000596251;ENST00000598727;ENST00000598200;ENST00000600559;ENST00000602201;ENST00000595337;ENST00000598090;ENST00000593804;ENST00000598415;ENST00000602075;ENST00000601135;ENST00000593561","GO:0005634(nucleus);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0042981(regulation of apoptotic process);GO:0003677(DNA binding);GO:0006915(apoptotic process);GO:0005730(nucleolus);GO:0005515(protein binding);GO:0008625(extrinsic apoptotic signaling pathway via death domain receptors);GO:0045892(negative regulation of transcription, DNA-templated);GO:0035556(intracellular signal transduction);GO:0006396(RNA processing);GO:2001238(positive regulation of extrinsic apoptotic signaling pathway);GO:0030159(receptor signaling complex scaffold activity);GO:0016075(rRNA catabolic process);GO:0019725(cellular homeostasis);GO:0030262(apoptotic nuclear changes);GO:0030262(apoptotic nuclear changes)","NA","NA","NA","death effector domain containing 2 [Source:HGNC Symbol;Acc:HGNC:24450]",{"v":5.91575948688712,"d":"5.92"},{"v":7.21838380653744,"d":"7.22"},{"v":0.819540723441364,"d":"0.82"},{"v":-0.287112455450143,"d":"-0.29"},{"v":0.693842565838933,"d":"0.69"},1,"down","no"]
["MSTRG.3942","HSPH1","ENST00000320027;ENST00000445273;ENST00000630972;ENST00000626866;ENST00000629751;ENST00000380405;ENST00000469538;ENST00000435381","GO:0005737(cytoplasm);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0005515(protein binding);GO:0006898(receptor-mediated endocytosis);GO:0005576(extracellular region);GO:0070062(extracellular exosome);GO:0043234(protein complex);GO:0006986(response to unfolded protein);GO:1900034(regulation of cellular response to heat);GO:0000774(adenyl-nucleotide exchange factor activity);GO:0071682(endocytic vesicle lumen);GO:0051135(positive regulation of NK T cell activation);GO:0045345(positive regulation of MHC class I biosynthetic process);GO:0043014(alpha-tubulin binding);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0051085(chaperone mediated protein folding requiring cofactor);GO:0061098(positive regulation of protein tyrosine kinase activity);GO:1903748(negative regulation of establishment of protein localization to mitochondrion);GO:1903751(negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide);GO:1903753(negative regulation of p38MAPK cascade);GO:2001234(negative regulation of apoptotic signaling pathway);GO:0005634(nucleus);GO:0005874(microtubule);GO:0005874(microtubule)","04141(Protein processing in endoplasmic reticulum);04141(Protein processing in endoplasmic reticulum)","K09485","NA","heat shock protein family H (Hsp110) member 1 [Source:HGNC Symbol;Acc:HGNC:16969]",{"v":2.28805341716329,"d":"2.29"},{"v":2.78653153349225,"d":"2.79"},{"v":0.821111618390969,"d":"0.82"},{"v":-0.28434974577871,"d":"-0.28"},{"v":0.694354613249398,"d":"0.69"},1,"down","no"]
["ENSG00000140463","BBS4","ENST00000268057;ENST00000569001;ENST00000569338;ENST00000565160;ENST00000561914;ENST00000568535;ENST00000562084;ENST00000566197;ENST00000564239;ENST00000395205;ENST00000562219;ENST00000566938","GO:0006810(transport);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0015031(protein transport);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0005856(cytoskeleton);GO:0042995(cell projection);GO:0005515(protein binding);GO:0050896(response to stimulus);GO:0005813(centrosome);GO:0005815(microtubule organizing center);GO:0034464(BBSome);GO:0005634(nucleus);GO:1905515(non-motile cilium assembly);GO:0000226(microtubule cytoskeleton organization);GO:0001764(neuron migration);GO:0001843(neural tube closure);GO:0001895(retina homeostasis);GO:0003085(negative regulation of systemic arterial blood pressure);GO:0007286(spermatid development);GO:0007608(sensory perception of smell);GO:0008104(protein localization);GO:0010629(negative regulation of gene expression);GO:0016358(dendrite development);GO:0019216(regulation of lipid metabolic process);GO:0021591(ventricular system development);GO:0021756(striatum development);GO:0021766(hippocampus development);GO:0021987(cerebral cortex development);GO:0030534(adult behavior);GO:0030837(negative regulation of actin filament polymerization);GO:0033210(leptin-mediated signaling pathway);GO:0033365(protein localization to organelle);GO:0034260(negative regulation of GTPase activity);GO:0035176(social behavior);GO:0035845(photoreceptor cell outer segment organization);GO:0038108(negative regulation of appetite by leptin-mediated signaling pathway);GO:0040018(positive regulation of multicellular organism growth);GO:0044321(response to leptin);GO:0045444(fat cell differentiation);GO:0045494(photoreceptor cell maintenance);GO:0045724(positive regulation of cilium assembly);GO:0046548(retinal rod cell development);GO:0048854(brain morphogenesis);GO:0051492(regulation of stress fiber assembly);GO:0060271(cilium assembly);GO:0060296(regulation of cilium beat frequency involved in ciliary motility);GO:0060324(face development);GO:0060613(fat pad development);GO:0071539(protein localization to centrosome);GO:1902855(regulation of non-motile cilium assembly);GO:1903546(protein localization to photoreceptor outer segment);GO:0001750(photoreceptor outer segment);GO:0001917(photoreceptor inner segment);GO:0031514(motile cilium);GO:0032391(photoreceptor connecting cilium);GO:0034451(centriolar satellite);GO:0005929(cilium);GO:0030030(cell projection organization);GO:0007601(visual perception);GO:0060170(ciliary membrane);GO:0007098(centrosome cycle);GO:0035869(ciliary transition zone);GO:0001947(heart looping);GO:0003777(microtubule motor activity);GO:0000242(pericentriolar material);GO:0097730(non-motile cilium);GO:0034452(dynactin binding);GO:0043014(alpha-tubulin binding);GO:0000281(mitotic cytokinesis);GO:0061512(protein localization to cilium);GO:0034454(microtubule anchoring at centrosome);GO:0005814(centriole);GO:0036064(ciliary basal body);GO:0001103(RNA polymerase II repressing transcription factor binding);GO:0032402(melanosome transport);GO:0050893(sensory processing);GO:0048487(beta-tubulin binding);GO:0032465(regulation of cytokinesis);GO:0046907(intracellular transport);GO:0051457(maintenance of protein location in nucleus);GO:0016021(integral component of membrane);GO:0016021(integral component of membrane)","NA","NA","NA","Bardet-Biedl syndrome 4 [Source:HGNC Symbol;Acc:HGNC:969]",{"v":0.722772473608098,"d":"0.72"},{"v":0.613735103639431,"d":"0.61"},{"v":1.17766194131976,"d":"1.18"},{"v":0.235925459731676,"d":"0.24"},{"v":0.695520250923418,"d":"0.70"},1,"up","no"]
["ENSG00000120334","CENPL","ENST00000356198;ENST00000367710;ENST00000493233;ENST00000495275","GO:0005634(nucleus);GO:0005694(chromosome);GO:0005515(protein binding);GO:0000775(chromosome, centromeric region);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0034080(CENP-A containing nucleosome assembly);GO:0007062(sister chromatid cohesion);GO:0007062(sister chromatid cohesion)","NA","NA","NA","centromere protein L [Source:HGNC Symbol;Acc:HGNC:17879]",{"v":0.514003881969882,"d":"0.51"},{"v":0.437391236467236,"d":"0.44"},{"v":1.17515816302457,"d":"1.18"},{"v":0.232854940326628,"d":"0.23"},{"v":0.697075478181115,"d":"0.70"},1,"up","no"]
["ENSG00000155893","PXYLP1","ENST00000286353;ENST00000636601;ENST00000637751;ENST00000505013;ENST00000513007;ENST00000508812;ENST00000502783;ENST00000511968;ENST00000512457;ENST00000505502;ENST00000393010","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016787(hydrolase activity);GO:0005794(Golgi apparatus);GO:0016311(dephosphorylation);GO:0000139(Golgi membrane);GO:0003993(acid phosphatase activity);GO:0005515(protein binding);GO:0016791(phosphatase activity);GO:0006024(glycosaminoglycan biosynthetic process);GO:0050650(chondroitin sulfate proteoglycan biosynthetic process);GO:0010909(positive regulation of heparan sulfate proteoglycan biosynthetic process);GO:0010909(positive regulation of heparan sulfate proteoglycan biosynthetic process)","NA","NA","NA","2-phosphoxylose phosphatase 1 [Source:HGNC Symbol;Acc:HGNC:26303]",{"v":0.51212592097561,"d":"0.51"},{"v":0.436096914821764,"d":"0.44"},{"v":1.17433970195574,"d":"1.17"},{"v":0.231849798087073,"d":"0.23"},{"v":0.697275966011762,"d":"0.70"},1,"up","no"]
["ENSG00000131725","WDR44","ENST00000254029;ENST00000371822;ENST00000371848;ENST00000493448","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005794(Golgi apparatus);GO:0005829(cytosol);GO:0048471(perinuclear region of cytoplasm);GO:0005768(endosome);GO:0010008(endosome membrane);GO:0010008(endosome membrane)","NA","NA","NA","WD repeat domain 44 [Source:HGNC Symbol;Acc:HGNC:30512]",{"v":4.04960306615897,"d":"4.05"},{"v":4.9185061894336,"d":"4.92"},{"v":0.823340036627119,"d":"0.82"},{"v":-0.280439713037519,"d":"-0.28"},{"v":0.698756344997803,"d":"0.70"},1,"down","no"]
["MSTRG.9973","CCT8","ENST00000286788;ENST00000470450;ENST00000481059;ENST00000480359;ENST00000475205;ENST00000626972;ENST00000496121;ENST00000540844;ENST00000494296;ENST00000432178","GO:0005524(ATP binding);GO:0005737(cytoplasm);GO:0000166(nucleotide binding);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0006457(protein folding);GO:0045111(intermediate filament cytoskeleton);GO:0005856(cytoskeleton);GO:0042995(cell projection);GO:0005874(microtubule);GO:0051082(unfolded protein binding);GO:0005815(microtubule organizing center);GO:0005576(extracellular region);GO:0061077(chaperone-mediated protein folding);GO:0005929(cilium);GO:0045296(cadherin binding);GO:0070062(extracellular exosome);GO:0043312(neutrophil degranulation);GO:0034774(secretory granule lumen);GO:1904813(ficolin-1-rich granule lumen);GO:0005515(protein binding);GO:0035578(azurophil granule lumen);GO:0050821(protein stabilization);GO:0032212(positive regulation of telomere maintenance via telomerase);GO:0005813(centrosome);GO:1904851(positive regulation of establishment of protein localization to telomere);GO:1904874(positive regulation of telomerase RNA localization to Cajal body);GO:0044183(protein binding involved in protein folding);GO:0006458('de novo' protein folding);GO:1904871(positive regulation of protein localization to Cajal body);GO:0005832(chaperonin-containing T-complex);GO:0042623(ATPase activity, coupled);GO:0007339(binding of sperm to zona pellucida);GO:0046931(pore complex assembly);GO:1901998(toxin transport);GO:0002199(zona pellucida receptor complex);GO:0044297(cell body);GO:0044297(cell body)","NA","NA","NA","chaperonin containing TCP1 subunit 8 [Source:HGNC Symbol;Acc:HGNC:1623]",{"v":14.4286396713559,"d":"14.43"},{"v":17.5143352029332,"d":"17.51"},{"v":0.823818860617643,"d":"0.82"},{"v":-0.279600939052566,"d":"-0.28"},{"v":0.69906216773511,"d":"0.70"},1,"down","no"]
["ENSG00000074660","SCARF1","ENST00000263071;ENST00000573852;ENST00000570902;ENST00000576012;ENST00000348987;ENST00000573867;ENST00000574545;ENST00000434376;ENST00000571272","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0007155(cell adhesion);GO:0005044(scavenger receptor activity);GO:0007165(signal transduction);GO:0006898(receptor-mediated endocytosis);GO:0005886(plasma membrane);GO:0004888(transmembrane signaling receptor activity);GO:0030666(endocytic vesicle membrane);GO:0010976(positive regulation of neuron projection development);GO:0016322(neuron remodeling);GO:0006707(cholesterol catabolic process);GO:0030169(low-density lipoprotein particle binding);GO:0016358(dendrite development);GO:0048680(positive regulation of axon regeneration);GO:0048680(positive regulation of axon regeneration)","NA","NA","NA","scavenger receptor class F member 1 [Source:HGNC Symbol;Acc:HGNC:16820]",{"v":1.58643744325741,"d":"1.59"},{"v":1.34998933460996,"d":"1.35"},{"v":1.1751481308671,"d":"1.18"},{"v":0.232842624192452,"d":"0.23"},{"v":0.700387626253202,"d":"0.70"},1,"up","no"]
["ENSG00000172113","NME6","ENST00000421967;ENST00000484959;ENST00000451657;ENST00000418431;ENST00000495734;ENST00000435684;ENST00000442597;ENST00000447724;ENST00000302378;ENST00000494209;ENST00000452211;ENST00000426689;ENST00000425930;ENST00000444069","GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0004550(nucleoside diphosphate kinase activity);GO:0006165(nucleoside diphosphate phosphorylation);GO:0006183(GTP biosynthetic process);GO:0006228(UTP biosynthetic process);GO:0006241(CTP biosynthetic process);GO:0005739(mitochondrion);GO:0046872(metal ion binding);GO:0006915(apoptotic process);GO:0009117(nucleotide metabolic process);GO:0005829(cytosol);GO:0030308(negative regulation of cell growth);GO:0015949(nucleobase-containing small molecule interconversion);GO:0045839(negative regulation of mitotic nuclear division);GO:0045839(negative regulation of mitotic nuclear division)","00230(Purine metabolism);00240(Pyrimidine metabolism);00983(Drug metabolism - other enzymes);00983(Drug metabolism - other enzymes)","K00940","EC:2.7.4.6","NME/NM23 nucleoside diphosphate kinase 6 [Source:HGNC Symbol;Acc:HGNC:20567]",{"v":0.76090049893978,"d":"0.76"},{"v":0.647710680661578,"d":"0.65"},{"v":1.17475366958993,"d":"1.17"},{"v":0.232358274307171,"d":"0.23"},{"v":0.701618469584953,"d":"0.70"},1,"up","no"]
["MSTRG.7045","MRPS23","ENST00000313608;ENST00000578444;ENST00000579768;ENST00000579380","GO:0003723(RNA binding);GO:0005739(mitochondrion);GO:0031965(nuclear membrane);GO:0030529(intracellular ribonucleoprotein complex);GO:0003735(structural constituent of ribosome);GO:0006412(translation);GO:0005840(ribosome);GO:0045111(intermediate filament cytoskeleton);GO:0005515(protein binding);GO:0005743(mitochondrial inner membrane);GO:0070125(mitochondrial translational elongation);GO:0070126(mitochondrial translational termination);GO:0070126(mitochondrial translational termination)","NA","NA","NA","mitochondrial ribosomal protein S23 [Source:HGNC Symbol;Acc:HGNC:14509]",{"v":1.00432332465904,"d":"1.00"},{"v":0.858203860322935,"d":"0.86"},{"v":1.17026195184105,"d":"1.17"},{"v":0.226831499314989,"d":"0.23"},{"v":0.702109561037979,"d":"0.70"},1,"up","no"]
["ENSG00000110799","VWF","ENST00000261405;ENST00000321023","GO:0007155(cell adhesion);GO:0005783(endoplasmic reticulum);GO:0042803(protein homodimerization activity);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0005578(proteinaceous extracellular matrix);GO:0007596(blood coagulation);GO:0042802(identical protein binding);GO:0070062(extracellular exosome);GO:0031012(extracellular matrix);GO:0047485(protein N-terminus binding);GO:0031091(platelet alpha granule);GO:0002576(platelet degranulation);GO:0005178(integrin binding);GO:0002020(protease binding);GO:0007599(hemostasis);GO:0030168(platelet activation);GO:0031093(platelet alpha granule lumen);GO:0030198(extracellular matrix organization);GO:0051087(chaperone binding);GO:0051260(protein homooligomerization);GO:0005518(collagen binding);GO:0031589(cell-substrate adhesion);GO:0009611(response to wounding);GO:0007597(blood coagulation, intrinsic pathway);GO:0019865(immunoglobulin binding);GO:0033093(Weibel-Palade body);GO:0033093(Weibel-Palade body)","04151(PI3K-Akt signaling pathway);04512(ECM-receptor interaction);04510(Focal adhesion);04610(Complement and coagulation cascades);04611(Platelet activation);05165(Human papillomavirus infection);05165(Human papillomavirus infection)","K03900","NA","von Willebrand factor [Source:HGNC Symbol;Acc:HGNC:12726]",{"v":0.673981065922433,"d":"0.67"},{"v":0.81883887133096,"d":"0.82"},{"v":0.823093638467515,"d":"0.82"},{"v":-0.280871528070187,"d":"-0.28"},{"v":0.703385913714516,"d":"0.70"},1,"down","no"]
["MSTRG.9228","TLK1","ENST00000360843;ENST00000359766;ENST00000413010;ENST00000470340;ENST00000431350;ENST00000478683;ENST00000409443;ENST00000466220;ENST00000486857","GO:0005634(nucleus);GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0016569(covalent chromatin modification);GO:0005515(protein binding);GO:0006974(cellular response to DNA damage stimulus);GO:0007049(cell cycle);GO:0006886(intracellular protein transport);GO:0035556(intracellular signal transduction);GO:0001672(regulation of chromatin assembly or disassembly);GO:0001672(regulation of chromatin assembly or disassembly)","NA","NA","NA","tousled like kinase 1 [Source:HGNC Symbol;Acc:HGNC:11841]",{"v":2.60411364965444,"d":"2.60"},{"v":3.15526418979266,"d":"3.16"},{"v":0.82532348894232,"d":"0.83"},{"v":-0.276968394414696,"d":"-0.28"},{"v":0.703698193157191,"d":"0.70"},1,"down","no"]
["ENSG00000196812","ZSCAN16","ENST00000340487","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0005515(protein binding)","NA","NA","NA","zinc finger and SCAN domain containing 16 [Source:HGNC Symbol;Acc:HGNC:20813]",{"v":3.794003,"d":"3.79"},{"v":3.245203,"d":"3.25"},{"v":1.16911114651379,"d":"1.17"},{"v":0.22541209231766,"d":"0.23"},{"v":0.705308698180903,"d":"0.71"},1,"up","no"]
["MSTRG.1496","COX20","ENST00000464757;ENST00000411948;ENST00000366528;ENST00000498262;ENST00000391839","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005739(mitochondrion);GO:0009060(aerobic respiration);GO:0031966(mitochondrial membrane);GO:0033617(mitochondrial respiratory chain complex IV assembly);GO:0033617(mitochondrial respiratory chain complex IV assembly)","NA","NA","NA","COX20, cytochrome c oxidase assembly factor [Source:HGNC Symbol;Acc:HGNC:26970]",{"v":1.2278752942023,"d":"1.23"},{"v":1.48943644387336,"d":"1.49"},{"v":0.824389183743311,"d":"0.82"},{"v":-0.278602518518506,"d":"-0.28"},{"v":0.706611044397769,"d":"0.71"},1,"down","no"]
["MSTRG.15128","NELFB","ENST00000634710;ENST00000343053","GO:0005634(nucleus);GO:0045892(negative regulation of transcription, DNA-templated);GO:0003723(RNA binding);GO:0005654(nucleoplasm);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0006366(transcription from RNA polymerase II promoter);GO:0006368(transcription elongation from RNA polymerase II promoter);GO:0050434(positive regulation of viral transcription);GO:0034244(negative regulation of transcription elongation from RNA polymerase II promoter);GO:0032021(NELF complex);GO:0032021(NELF complex)","NA","NA","NA","negative elongation factor complex member B [Source:HGNC Symbol;Acc:HGNC:24324]",{"v":5.79402249851742,"d":"5.79"},{"v":7.00153798480356,"d":"7.00"},{"v":0.827535680173844,"d":"0.83"},{"v":-0.273106578133511,"d":"-0.27"},{"v":0.706921945647656,"d":"0.71"},1,"down","no"]
["MSTRG.14374","NSMAF","ENST00000523177;ENST00000427130;ENST00000038176;ENST00000519871;ENST00000522645;ENST00000519166;ENST00000519174;ENST00000518229;ENST00000521972;ENST00000524148;ENST00000521712;ENST00000523106;ENST00000517612;ENST00000519858;ENST00000519227;ENST00000523982","GO:0043085(positive regulation of catalytic activity);GO:0005515(protein binding);GO:0005829(cytosol);GO:0005737(cytoplasm);GO:0007165(signal transduction);GO:0005057(signal transducer activity, downstream of receptor);GO:2000304(positive regulation of ceramide biosynthetic process);GO:0006672(ceramide metabolic process);GO:0016230(sphingomyelin phosphodiesterase activator activity);GO:0043065(positive regulation of apoptotic process);GO:0043065(positive regulation of apoptotic process)","04071(Sphingolipid signaling pathway);04071(Sphingolipid signaling pathway)","K18953","NA","neutral sphingomyelinase activation associated factor [Source:HGNC Symbol;Acc:HGNC:8017]",{"v":6.11678368467153,"d":"6.12"},{"v":7.39193347802109,"d":"7.39"},{"v":0.827494417104666,"d":"0.83"},{"v":-0.273178516432863,"d":"-0.27"},{"v":0.707722050901838,"d":"0.71"},1,"down","no"]
["ENSG00000183479","TREX2","ENST00000338525;ENST00000370231;ENST00000393862;ENST00000330912","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0016787(hydrolase activity);GO:0006259(DNA metabolic process);GO:0042803(protein homodimerization activity);GO:0006281(DNA repair);GO:0090305(nucleic acid phosphodiester bond hydrolysis);GO:0006974(cellular response to DNA damage stimulus);GO:0004527(exonuclease activity);GO:0000287(magnesium ion binding);GO:0004518(nuclease activity);GO:0008408(3'-5' exonuclease activity);GO:0008853(exodeoxyribonuclease III activity);GO:0008296(3'-5'-exodeoxyribonuclease activity);GO:0008296(3'-5'-exodeoxyribonuclease activity)","NA","NA","NA","three prime repair exonuclease 2 [Source:HGNC Symbol;Acc:HGNC:12270]",{"v":1.93114966924494,"d":"1.93"},{"v":1.65112169723757,"d":"1.65"},{"v":1.16959862648276,"d":"1.17"},{"v":0.226013522176176,"d":"0.23"},{"v":0.70828291316465,"d":"0.71"},1,"up","no"]
["ENSG00000141034","GID4","ENST00000268719;ENST00000376345;ENST00000481836;ENST00000459843","GO:0016567(protein ubiquitination);GO:0061630(ubiquitin protein ligase activity);GO:0043161(proteasome-mediated ubiquitin-dependent protein catabolic process);GO:0043161(proteasome-mediated ubiquitin-dependent protein catabolic process)","NA","NA","NA","GID complex subunit 4 homolog [Source:HGNC Symbol;Acc:HGNC:28453]",{"v":2.5092508159309,"d":"2.51"},{"v":2.15382336410749,"d":"2.15"},{"v":1.16502163443226,"d":"1.17"},{"v":0.220356745951085,"d":"0.22"},{"v":0.709762266551174,"d":"0.71"},1,"up","no"]
["MSTRG.15091","UBAC1","ENST00000371756;ENST00000465873;ENST00000478485;ENST00000489050;ENST00000471163;ENST00000486258","GO:0005737(cytoplasm);GO:0005794(Golgi apparatus);GO:0005829(cytosol);GO:0016567(protein ubiquitination);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0070062(extracellular exosome);GO:0070062(extracellular exosome)","NA","NA","NA","UBA domain containing 1 [Source:HGNC Symbol;Acc:HGNC:30221]",{"v":3.60962198455858,"d":"3.61"},{"v":4.36914006545821,"d":"4.37"},{"v":0.826163027616288,"d":"0.83"},{"v":-0.27550159662524,"d":"-0.28"},{"v":0.710260342906841,"d":"0.71"},1,"down","no"]
["MSTRG.10997","GNL3","ENST00000394799;ENST00000418458;ENST00000492349;ENST00000496254;ENST00000468146;ENST00000462550;ENST00000460073;ENST00000497356;ENST00000474423;ENST00000484022","GO:0003723(RNA binding);GO:0005634(nucleus);GO:0016020(membrane);GO:0005525(GTP binding);GO:0000166(nucleotide binding);GO:0005730(nucleolus);GO:0005515(protein binding);GO:0016604(nuclear body);GO:0005615(extracellular space);GO:0003924(GTPase activity);GO:0042254(ribosome biogenesis);GO:0042127(regulation of cell proliferation);GO:1902895(positive regulation of pri-miRNA transcription from RNA polymerase II promoter);GO:0019827(stem cell population maintenance);GO:0032206(positive regulation of telomere maintenance);GO:0048027(mRNA 5'-UTR binding);GO:0017145(stem cell division);GO:0033235(positive regulation of protein sumoylation);GO:0008283(cell proliferation);GO:1904816(positive regulation of protein localization to chromosome, telomeric region);GO:0005654(nucleoplasm);GO:0005654(nucleoplasm)","03008(Ribosome biogenesis in eukaryotes);03008(Ribosome biogenesis in eukaryotes)","K14538","NA","G protein nucleolar 3 [Source:HGNC Symbol;Acc:HGNC:29931]",{"v":5.0651892624219,"d":"5.07"},{"v":4.35846791877417,"d":"4.36"},{"v":1.16214902961738,"d":"1.16"},{"v":0.21679508638761,"d":"0.22"},{"v":0.711661839210323,"d":"0.71"},1,"up","no"]
["MSTRG.7144","AC005332.9","ENST00000620266","NA","NA","NA","NA",null,{"v":3.913727,"d":"3.91"},{"v":3.363607,"d":"3.36"},{"v":1.16355061694187,"d":"1.16"},{"v":0.218533972430097,"d":"0.22"},{"v":0.712975249658495,"d":"0.71"},1,"up","no"]
["MSTRG.6014","LRRC29","ENST00000433915;ENST00000424285;ENST00000629962;ENST00000409037;ENST00000637247;ENST00000409509","GO:0005515(protein binding);GO:0005515(protein binding)","NA","NA","NA","leucine rich repeat containing 29 [Source:HGNC Symbol;Acc:HGNC:13605]",{"v":0.350110190238689,"d":"0.35"},{"v":0.425512777342358,"d":"0.43"},{"v":0.82279595086518,"d":"0.82"},{"v":-0.281393400782779,"d":"-0.28"},{"v":0.713428790315585,"d":"0.71"},1,"down","no"]
["MSTRG.12533","STK10","ENST00000176763;ENST00000522879;ENST00000517360;ENST00000521322;ENST00000519441;ENST00000522936;ENST00000517381;ENST00000519710;ENST00000518267;ENST00000517527;ENST00000520476;ENST00000523615;ENST00000519269;ENST00000517775;ENST00000517524;ENST00000523603","GO:0016020(membrane);GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0042803(protein homodimerization activity);GO:0005886(plasma membrane);GO:0007049(cell cycle);GO:0042802(identical protein binding);GO:0005737(cytoplasm);GO:0005515(protein binding);GO:0070062(extracellular exosome);GO:0043312(neutrophil degranulation);GO:0035579(specific granule membrane);GO:0042981(regulation of apoptotic process);GO:0046777(protein autophosphorylation);GO:0007346(regulation of mitotic cell cycle);GO:0031098(stress-activated protein kinase signaling cascade);GO:0023014(signal transduction by protein phosphorylation);GO:0032147(activation of protein kinase activity);GO:0071593(lymphocyte aggregation);GO:2000401(regulation of lymphocyte migration);GO:2000401(regulation of lymphocyte migration)","04914(Progesterone-mediated oocyte maturation);04914(Progesterone-mediated oocyte maturation)","K08837","EC:2.7.11.1","serine/threonine kinase 10 [Source:HGNC Symbol;Acc:HGNC:11388]",{"v":26.5108148733899,"d":"26.51"},{"v":31.8535284201255,"d":"31.85"},{"v":0.832272473043834,"d":"0.83"},{"v":-0.264872173305347,"d":"-0.26"},{"v":0.715798959313303,"d":"0.72"},1,"down","no"]
["MSTRG.9853","RAB22A","ENST00000244040;ENST00000488949","GO:0006810(transport);GO:0016020(membrane);GO:0015031(protein transport);GO:0005525(GTP binding);GO:0000166(nucleotide binding);GO:0003924(GTPase activity);GO:0005886(plasma membrane);GO:0042995(cell projection);GO:0005515(protein binding);GO:0031410(cytoplasmic vesicle);GO:0005768(endosome);GO:0006897(endocytosis);GO:0070062(extracellular exosome);GO:0030670(phagocytic vesicle membrane);GO:0005769(early endosome);GO:0010008(endosome membrane);GO:0005770(late endosome);GO:0001726(ruffle);GO:0019003(GDP binding);GO:0045335(phagocytic vesicle);GO:0007032(endosome organization);GO:0097494(regulation of vesicle size);GO:0015629(actin cytoskeleton);GO:0015629(actin cytoskeleton)","04144(Endocytosis);04144(Endocytosis)","K07891","NA","RAB22A, member RAS oncogene family [Source:HGNC Symbol;Acc:HGNC:9764]",{"v":3.19727314894992,"d":"3.20"},{"v":2.75966327043619,"d":"2.76"},{"v":1.15857365034415,"d":"1.16"},{"v":0.212349759014026,"d":"0.21"},{"v":0.716050629969575,"d":"0.72"},1,"up","no"]
["ENSG00000114023","FAM162A","ENST00000477892;ENST00000232125;ENST00000469967","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005829(cytosol);GO:0005739(mitochondrion);GO:0005515(protein binding);GO:0006915(apoptotic process);GO:0070062(extracellular exosome);GO:0043065(positive regulation of apoptotic process);GO:0090200(positive regulation of release of cytochrome c from mitochondria);GO:0006919(activation of cysteine-type endopeptidase activity involved in apoptotic process);GO:0071456(cellular response to hypoxia);GO:0051402(neuron apoptotic process);GO:0051402(neuron apoptotic process)","NA","NA","NA","family with sequence similarity 162 member A [Source:HGNC Symbol;Acc:HGNC:17865]",{"v":2.0715656216715,"d":"2.07"},{"v":1.78773455101503,"d":"1.79"},{"v":1.15876578012956,"d":"1.16"},{"v":0.212588985676823,"d":"0.21"},{"v":0.717095379226773,"d":"0.72"},1,"up","no"]
["ENSG00000246898","LINC00920","ENST00000499966","NA","NA","NA","NA","long intergenic non-protein coding RNA 920 [Source:HGNC Symbol;Acc:HGNC:48611]",{"v":0.286578,"d":"0.29"},{"v":0.350484,"d":"0.35"},{"v":0.817663573800801,"d":"0.82"},{"v":-0.290420723903528,"d":"-0.29"},{"v":0.718228551746566,"d":"0.72"},1,"down","no"]
["ENSG00000069509","FUNDC1","ENST00000378045","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005739(mitochondrion);GO:0005515(protein binding);GO:0005741(mitochondrial outer membrane);GO:0006914(autophagy);GO:0001666(response to hypoxia);GO:0016236(macroautophagy);GO:0000422(mitophagy);GO:0031307(integral component of mitochondrial outer membrane);GO:0010243(response to organonitrogen compound)","04137(Mitophagy - animal)","K17986","NA","FUN14 domain containing 1 [Source:HGNC Symbol;Acc:HGNC:28746]",{"v":1.10691381558256,"d":"1.11"},{"v":1.34865969692638,"d":"1.35"},{"v":0.820751015326725,"d":"0.82"},{"v":-0.284983465372779,"d":"-0.28"},{"v":0.718759986034253,"d":"0.72"},1,"down","no"]
["ENSG00000166171","DPCD","ENST00000370151;ENST00000475443;ENST00000370147;ENST00000470165","GO:0005634(nucleus);GO:0005515(protein binding);GO:0003351(epithelial cilium movement);GO:0007283(spermatogenesis);GO:0007368(determination of left/right symmetry);GO:0021591(ventricular system development);GO:0021670(lateral ventricle development);GO:0021678(third ventricle development);GO:0030317(flagellated sperm motility);GO:0060972(left/right pattern formation);GO:0060972(left/right pattern formation)","NA","NA","NA","deleted in primary ciliary dyskinesia homolog (mouse) [Source:HGNC Symbol;Acc:HGNC:24542]",{"v":1.02003524912689,"d":"1.02"},{"v":1.24530354947614,"d":"1.25"},{"v":0.819105710857394,"d":"0.82"},{"v":-0.28787844193658,"d":"-0.29"},{"v":0.720512453936507,"d":"0.72"},1,"down","no"]
["ENSG00000117593","DARS2","ENST00000361951","GO:0003676(nucleic acid binding);GO:0005737(cytoplasm);GO:0006412(translation);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0005634(nucleus);GO:0005739(mitochondrion);GO:0042803(protein homodimerization activity);GO:0016874(ligase activity);GO:0005759(mitochondrial matrix);GO:0004812(aminoacyl-tRNA ligase activity);GO:0006418(tRNA aminoacylation for protein translation);GO:0005515(protein binding);GO:0000049(tRNA binding);GO:0004815(aspartate-tRNA ligase activity);GO:0050560(aspartate-tRNA(Asn) ligase activity);GO:0043039(tRNA aminoacylation);GO:0070145(mitochondrial asparaginyl-tRNA aminoacylation)","00970(Aminoacyl-tRNA biosynthesis)","K01876","EC:6.1.1.12","aspartyl-tRNA synthetase 2, mitochondrial [Source:HGNC Symbol;Acc:HGNC:25538]",{"v":2.07205930550285,"d":"2.07"},{"v":2.48480455733261,"d":"2.48"},{"v":0.833892267055066,"d":"0.83"},{"v":-0.262067085108211,"d":"-0.26"},{"v":0.720650431238215,"d":"0.72"},1,"down","no"]
["MSTRG.10547","RRP7A","ENST00000323013;ENST00000416699;ENST00000483303","GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0005515(protein binding);GO:0000028(ribosomal small subunit assembly);GO:0005654(nucleoplasm);GO:0006364(rRNA processing);GO:0032545(CURI complex);GO:0034456(UTP-C complex);GO:0001825(blastocyst formation);GO:0005737(cytoplasm);GO:0005737(cytoplasm)","03008(Ribosome biogenesis in eukaryotes);03008(Ribosome biogenesis in eukaryotes)","K14545","NA","ribosomal RNA processing 7 homolog A [Source:HGNC Symbol;Acc:HGNC:24286]",{"v":4.84995683047526,"d":"4.85"},{"v":4.20054806957374,"d":"4.20"},{"v":1.15460095924278,"d":"1.15"},{"v":0.207394329050256,"d":"0.21"},{"v":0.721853115752186,"d":"0.72"},1,"up","no"]
["ENSG00000170921","TANC2","ENST00000424789;ENST00000580466;ENST00000579541;ENST00000583016;ENST00000389520;ENST00000580068;ENST00000583545","GO:0001701(in utero embryonic development);GO:0001701(in utero embryonic development)","NA","NA","NA","tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 [Source:HGNC Symbol;Acc:HGNC:30212]",{"v":0.551682923117292,"d":"0.55"},{"v":0.660453394603341,"d":"0.66"},{"v":0.835309391434993,"d":"0.84"},{"v":-0.259617436444077,"d":"-0.26"},{"v":0.722880283947455,"d":"0.72"},1,"down","no"]
["MSTRG.921","ENSA","ENST00000369014;ENST00000271690;ENST00000503345;ENST00000362052;ENST00000638926;ENST00000361532;ENST00000356527;ENST00000361631;ENST00000513281;ENST00000369016;ENST00000339643;ENST00000503241;ENST00000354702","GO:0005737(cytoplasm);GO:0051301(cell division);GO:0050790(regulation of catalytic activity);GO:0005515(protein binding);GO:0043086(negative regulation of catalytic activity);GO:0007049(cell cycle);GO:0065009(regulation of molecular function);GO:0004864(protein phosphatase inhibitor activity);GO:0005654(nucleoplasm);GO:0006810(transport);GO:0005102(receptor binding);GO:0000278(mitotic cell cycle);GO:0007584(response to nutrient);GO:0008200(ion channel inhibitor activity);GO:0019212(phosphatase inhibitor activity);GO:0019870(potassium channel inhibitor activity);GO:0019888(protein phosphatase regulator activity);GO:0051721(protein phosphatase 2A binding);GO:0000086(G2/M transition of mitotic cell cycle);GO:0035308(negative regulation of protein dephosphorylation);GO:0050796(regulation of insulin secretion);GO:0009749(response to glucose);GO:0009749(response to glucose)","NA","NA","NA","endosulfine alpha [Source:HGNC Symbol;Acc:HGNC:3360]",{"v":4.66271552302931,"d":"4.66"},{"v":5.58422796195157,"d":"5.58"},{"v":0.834979437587249,"d":"0.83"},{"v":-0.260187425032618,"d":"-0.26"},{"v":0.724305056580305,"d":"0.72"},1,"down","no"]
["ENSG00000110619","CARS","ENST00000526890;ENST00000397111;ENST00000278224;ENST00000527330;ENST00000466442;ENST00000380525;ENST00000465207;ENST00000524825;ENST00000529772;ENST00000465240;ENST00000531387;ENST00000465331;ENST00000484484;ENST00000470221;ENST00000439280","GO:0005737(cytoplasm);GO:0006412(translation);GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0005829(cytosol);GO:0042803(protein homodimerization activity);GO:0016874(ligase activity);GO:0004812(aminoacyl-tRNA ligase activity);GO:0006418(tRNA aminoacylation for protein translation);GO:0000049(tRNA binding);GO:0004817(cysteine-tRNA ligase activity);GO:0006423(cysteinyl-tRNA aminoacylation);GO:0005515(protein binding);GO:0005515(protein binding)","00970(Aminoacyl-tRNA biosynthesis);00970(Aminoacyl-tRNA biosynthesis)","K01883","EC:6.1.1.16","cysteinyl-tRNA synthetase [Source:HGNC Symbol;Acc:HGNC:1493]",{"v":2.14756591611039,"d":"2.15"},{"v":2.56994922197868,"d":"2.57"},{"v":0.835645271799151,"d":"0.84"},{"v":-0.259037441124167,"d":"-0.26"},{"v":0.724951680636725,"d":"0.72"},1,"down","no"]
["MSTRG.6232","RNF166","ENST00000568683;ENST00000312838;ENST00000569478;ENST00000564894;ENST00000565083;ENST00000562499;ENST00000537718;ENST00000567844;ENST00000541206","GO:0046872(metal ion binding);GO:0005622(intracellular);GO:0061630(ubiquitin protein ligase activity);GO:0000209(protein polyubiquitination);GO:0032436(positive regulation of proteasomal ubiquitin-dependent protein catabolic process);GO:0031624(ubiquitin conjugating enzyme binding);GO:0031624(ubiquitin conjugating enzyme binding)","NA","NA","NA","ring finger protein 166 [Source:HGNC Symbol;Acc:HGNC:28856]",{"v":20.6617268129267,"d":"20.66"},{"v":24.6583125050068,"d":"24.66"},{"v":0.837921362572212,"d":"0.84"},{"v":-0.255113238970449,"d":"-0.26"},{"v":0.726418853848081,"d":"0.73"},1,"down","no"]
["MSTRG.13403","SOD2","ENST00000444946;ENST00000367054;ENST00000367055;ENST00000337404;ENST00000538183;ENST00000546260;MSTRG.13403.1;ENST00000541573;ENST00000452684;ENST00000545162;ENST00000401980;ENST00000535459;ENST00000535561;ENST00000546087;ENST00000537657;ENST00000535372;ENST00000540491","GO:0046872(metal ion binding);GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0004784(superoxide dismutase activity);GO:0006801(superoxide metabolic process);GO:0003677(DNA binding);GO:0019825(oxygen binding);GO:0019899(enzyme binding);GO:0030145(manganese ion binding);GO:0042802(identical protein binding);GO:0000302(response to reactive oxygen species);GO:0000303(response to superoxide);GO:0001306(age-dependent response to oxidative stress);GO:0001666(response to hypoxia);GO:0001836(release of cytochrome c from mitochondria);GO:0001889(liver development);GO:0003032(detection of oxygen);GO:0003069(acetylcholine-mediated vasodilation involved in regulation of systemic arterial blood pressure);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0006749(glutathione metabolic process);GO:0006979(response to oxidative stress);GO:0007005(mitochondrion organization);GO:0007507(heart development);GO:0007568(aging);GO:0007626(locomotory behavior);GO:0008217(regulation of blood pressure);GO:0008630(intrinsic apoptotic signaling pathway in response to DNA damage);GO:0008631(intrinsic apoptotic signaling pathway in response to oxidative stress);GO:0008637(apoptotic mitochondrial changes);GO:0009314(response to radiation);GO:0009409(response to cold);GO:0009791(post-embryonic development);GO:0010042(response to manganese ion);GO:0010043(response to zinc ion);GO:0010269(response to selenium ion);GO:0010332(response to gamma radiation);GO:0014823(response to activity);GO:0019430(removal of superoxide radicals);GO:0022904(respiratory electron transport chain);GO:0030097(hemopoiesis);GO:0031667(response to nutrient levels);GO:0032496(response to lipopolysaccharide);GO:0033591(response to L-ascorbic acid);GO:0034021(response to silicon dioxide);GO:0035900(response to isolation stress);GO:0035902(response to immobilization stress);GO:0042311(vasodilation);GO:0042493(response to drug);GO:0042542(response to hydrogen peroxide);GO:0042554(superoxide anion generation);GO:0042743(hydrogen peroxide metabolic process);GO:0043066(negative regulation of apoptotic process);GO:0045429(positive regulation of nitric oxide biosynthetic process);GO:0045599(negative regulation of fat cell differentiation);GO:0046686(response to cadmium ion);GO:0048147(negative regulation of fibroblast proliferation);GO:0048666(neuron development);GO:0048678(response to axon injury);GO:0048773(erythrophore differentiation);GO:0050665(hydrogen peroxide biosynthetic process);GO:0050790(regulation of catalytic activity);GO:0051260(protein homooligomerization);GO:0051602(response to electrical stimulus);GO:0051881(regulation of mitochondrial membrane potential);GO:0055072(iron ion homeostasis);GO:0055093(response to hyperoxia);GO:0071000(response to magnetism);GO:0071361(cellular response to ethanol);GO:0005737(cytoplasm);GO:0005739(mitochondrion);GO:0005743(mitochondrial inner membrane);GO:0042645(mitochondrial nucleoid);GO:0043209(myelin sheath);GO:0008285(negative regulation of cell proliferation);GO:0030335(positive regulation of cell migration);GO:0005759(mitochondrial matrix);GO:0070062(extracellular exosome);GO:0035722(interleukin-12-mediated signaling pathway);GO:0051289(protein homotetramerization);GO:0034599(cellular response to oxidative stress);GO:0043524(negative regulation of neuron apoptotic process);GO:1902176(negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway);GO:0001315(age-dependent response to reactive oxygen species);GO:0032364(oxygen homeostasis);GO:0032364(oxygen homeostasis)","04068(FoxO signaling pathway);04146(Peroxisome);04211(Longevity regulating pathway - mammal);04213(Longevity regulating pathway - multiple species);05016(Huntington's disease);05016(Huntington's disease)","K04564","EC:1.15.1.1","superoxide dismutase 2 [Source:HGNC Symbol;Acc:HGNC:11180]",{"v":13.7710186403024,"d":"13.77"},{"v":16.4231711160063,"d":"16.42"},{"v":0.838511548289291,"d":"0.84"},{"v":-0.25409744163446,"d":"-0.25"},{"v":0.727751192102315,"d":"0.73"},1,"down","no"]
["MSTRG.14458","PTDSS1","ENST00000522072;ENST00000517309;ENST00000518776;ENST00000337004;ENST00000517982;ENST00000517557","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016740(transferase activity);GO:0006629(lipid metabolic process);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0008654(phospholipid biosynthetic process);GO:0006659(phosphatidylserine biosynthetic process);GO:0006659(phosphatidylserine biosynthetic process)","00564(Glycerophospholipid metabolism);00564(Glycerophospholipid metabolism)","K08729","EC:2.7.8.-","phosphatidylserine synthase 1 [Source:HGNC Symbol;Acc:HGNC:9587]",{"v":3.98930580063542,"d":"3.99"},{"v":4.76155766449563,"d":"4.76"},{"v":0.837815286871673,"d":"0.84"},{"v":-0.255295886867278,"d":"-0.26"},{"v":0.728547812420768,"d":"0.73"},1,"down","no"]
["MSTRG.5307","RCN2","ENST00000560833;ENST00000394885;ENST00000558598;ENST00000557805;ENST00000320963","GO:0046872(metal ion binding);GO:0005783(endoplasmic reticulum);GO:0005730(nucleolus);GO:0005509(calcium ion binding);GO:0005515(protein binding);GO:0005788(endoplasmic reticulum lumen);GO:0005788(endoplasmic reticulum lumen)","NA","NA","NA","reticulocalbin 2 [Source:HGNC Symbol;Acc:HGNC:9935]",{"v":0.788576796386865,"d":"0.79"},{"v":0.943318271084939,"d":"0.94"},{"v":0.835960481799954,"d":"0.84"},{"v":-0.258493351216116,"d":"-0.26"},{"v":0.72958196539227,"d":"0.73"},1,"down","no"]
["MSTRG.807","ST7L","ENST00000358039;ENST00000479436;ENST00000369664;ENST00000369669;ENST00000490715;ENST00000369666;ENST00000361846;ENST00000473206;ENST00000470519;ENST00000477332;ENST00000470683;ENST00000497457;ENST00000463235;ENST00000498197;ENST00000459630;ENST00000485753","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0030308(negative regulation of cell growth);GO:0030308(negative regulation of cell growth)","NA","NA","NA","suppression of tumorigenicity 7 like [Source:HGNC Symbol;Acc:HGNC:18441]",{"v":0.316289262852916,"d":"0.32"},{"v":0.383202636912834,"d":"0.38"},{"v":0.825383837128609,"d":"0.83"},{"v":-0.276862907478581,"d":"-0.28"},{"v":0.729928162165624,"d":"0.73"},1,"down","no"]
["MSTRG.404","ZMYM6;AC114490.1;TMEM35B;AC114490.2","ENST00000493328;ENST00000417456;ENST00000357182;ENST00000373337;ENST00000472971;ENST00000487874;ENST00000415531;ENST00000460607;ENST00000317538;ENST00000311990;ENST00000471566;ENST00000373333","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0005737(cytoplasm);GO:0000981(RNA polymerase II transcription factor activity, sequence-specific DNA binding);GO:0007010(cytoskeleton organization);GO:0022604(regulation of cell morphogenesis);GO:0005654(nucleoplasm);GO:0003677(DNA binding);GO:0007275(multicellular organism development);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0007275(multicellular organism development)","NA","NA","NA","zinc finger MYM-type containing 6 [Source:HGNC Symbol;Acc:HGNC:13050];transmembrane protein 35B [Source:HGNC Symbol;Acc:HGNC:40021]",{"v":2.08652792050817,"d":"2.09"},{"v":1.81893571905626,"d":"1.82"},{"v":1.14711471034872,"d":"1.15"},{"v":0.198009666660142,"d":"0.20"},{"v":0.731223256223733,"d":"0.73"},1,"up","no"]
["ENSG00000144736","SHQ1","ENST00000325599;ENST00000468347;ENST00000444040;ENST00000475558;ENST00000468371","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0005515(protein binding);GO:1904874(positive regulation of telomerase RNA localization to Cajal body);GO:0043065(positive regulation of apoptotic process);GO:0051082(unfolded protein binding);GO:0000493(box H/ACA snoRNP assembly);GO:0022618(ribonucleoprotein complex assembly);GO:2000233(negative regulation of rRNA processing);GO:2000233(negative regulation of rRNA processing)","NA","NA","NA","SHQ1, H/ACA ribonucleoprotein assembly factor [Source:HGNC Symbol;Acc:HGNC:25543]",{"v":0.862008802259887,"d":"0.86"},{"v":0.752979130970724,"d":"0.75"},{"v":1.14479773317038,"d":"1.14"},{"v":0.1950927204799,"d":"0.20"},{"v":0.73332767320136,"d":"0.73"},1,"up","no"]
["ENSG00000065029","ZNF76","ENST00000486891;ENST00000339411;ENST00000373953;ENST00000229405;ENST00000491400;ENST00000498555;ENST00000482946;ENST00000460229;ENST00000484932;ENST00000479226;ENST00000469195","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006366(transcription from RNA polymerase II promoter);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0001228(transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding);GO:0043565(sequence-specific DNA binding);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0006359(regulation of transcription from RNA polymerase III promoter);GO:0006359(regulation of transcription from RNA polymerase III promoter)","NA","NA","NA","zinc finger protein 76 [Source:HGNC Symbol;Acc:HGNC:13149]",{"v":2.10068619561055,"d":"2.10"},{"v":1.82868058668434,"d":"1.83"},{"v":1.14874418797183,"d":"1.15"},{"v":0.200057562271279,"d":"0.20"},{"v":0.733839647566862,"d":"0.73"},1,"up","no"]
["MSTRG.7696","TNFAIP8L1","ENST00000598107;ENST00000536716;ENST00000327473","GO:0005737(cytoplasm);GO:0005515(protein binding);GO:0032007(negative regulation of TOR signaling);GO:0032007(negative regulation of TOR signaling)","NA","NA","NA","TNF alpha induced protein 8 like 1 [Source:HGNC Symbol;Acc:HGNC:28279]",{"v":1.94398055647218,"d":"1.94"},{"v":1.69543908774561,"d":"1.70"},{"v":1.14659415989816,"d":"1.15"},{"v":0.1973548358957,"d":"0.20"},{"v":0.735998038743493,"d":"0.74"},1,"up","no"]
["ENSG00000229183","PGA4","ENST00000378149;ENST00000539581;ENST00000537932;ENST00000544899;ENST00000624544","GO:0016787(hydrolase activity);GO:0008233(peptidase activity);GO:0006508(proteolysis);GO:0005576(extracellular region);GO:0004190(aspartic-type endopeptidase activity);GO:0070062(extracellular exosome);GO:0044267(cellular protein metabolic process);GO:0006914(autophagy);GO:0030163(protein catabolic process);GO:0097486(multivesicular body lumen);GO:0007586(digestion);GO:0007586(digestion)","04974(Protein digestion and absorption);04974(Protein digestion and absorption)","K06002","EC:3.4.23.1","pepsinogen 4, group I (pepsinogen A) [Source:HGNC Symbol;Acc:HGNC:8886]",{"v":0.212036643356643,"d":"0.21"},{"v":0.255766242618493,"d":"0.26"},{"v":0.829025133206972,"d":"0.83"},{"v":-0.270512254923366,"d":"-0.27"},{"v":0.73705326285304,"d":"0.74"},1,"down","no"]
["MSTRG.749","VAV3","ENST00000370056;ENST00000524574;ENST00000490388;ENST00000525231;ENST00000533398;ENST00000527011;ENST00000343258;ENST00000469325;ENST00000529033;ENST00000525460;ENST00000529809;ENST00000479977","GO:0046872(metal ion binding);GO:0035556(intracellular signal transduction);GO:0009967(positive regulation of signal transduction);GO:0005089(Rho guanyl-nucleotide exchange factor activity);GO:0035023(regulation of Rho protein signal transduction);GO:0043547(positive regulation of GTPase activity);GO:0005515(protein binding);GO:0006974(cellular response to DNA damage stimulus);GO:0005085(guanyl-nucleotide exchange factor activity);GO:0038095(Fc-epsilon receptor signaling pathway);GO:0038096(Fc-gamma receptor signaling pathway involved in phagocytosis);GO:0030890(positive regulation of B cell proliferation);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0051056(regulation of small GTPase mediated signal transduction);GO:0030168(platelet activation);GO:0050853(B cell receptor signaling pathway);GO:0048013(ephrin receptor signaling pathway);GO:0048010(vascular endothelial growth factor receptor signaling pathway);GO:0001525(angiogenesis);GO:0007264(small GTPase mediated signal transduction);GO:0005070(SH3/SH2 adaptor activity);GO:0043087(regulation of GTPase activity);GO:0008361(regulation of cell size);GO:0043065(positive regulation of apoptotic process);GO:0005096(GTPase activator activity);GO:0042493(response to drug);GO:0005154(epidermal growth factor receptor binding);GO:0030676(Rac guanyl-nucleotide exchange factor activity);GO:0006906(vesicle fusion);GO:0007229(integrin-mediated signaling pathway);GO:0016477(cell migration);GO:0030031(cell projection assembly);GO:0030032(lamellipodium assembly);GO:0030593(neutrophil chemotaxis);GO:0043552(positive regulation of phosphatidylinositol 3-kinase activity);GO:0045785(positive regulation of cell adhesion);GO:0005737(cytoplasm);GO:0005886(plasma membrane);GO:0005622(intracellular);GO:0005622(intracellular)","04024(cAMP signaling pathway);04510(Focal adhesion);04810(Regulation of actin cytoskeleton);04650(Natural killer cell mediated cytotoxicity);04660(T cell receptor signaling pathway);04662(B cell receptor signaling pathway);04664(Fc epsilon RI signaling pathway);04666(Fc gamma R-mediated phagocytosis);04670(Leukocyte transendothelial migration);04062(Chemokine signaling pathway);04062(Chemokine signaling pathway)","K05730","NA","vav guanine nucleotide exchange factor 3 [Source:HGNC Symbol;Acc:HGNC:12659]",{"v":2.49024812034108,"d":"2.49"},{"v":2.95593665369275,"d":"2.96"},{"v":0.842456524645107,"d":"0.84"},{"v":-0.247325857610395,"d":"-0.25"},{"v":0.738317521670902,"d":"0.74"},1,"down","no"]
["MSTRG.10230","BCR","ENST00000305877;ENST00000419722;ENST00000471452;ENST00000487968;ENST00000458056;ENST00000479188;ENST00000436990;ENST00000480973;ENST00000475025;ENST00000478978","GO:0016020(membrane);GO:0000166(nucleotide binding);GO:0004674(protein serine/threonine kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0035556(intracellular signal transduction);GO:0007165(signal transduction);GO:0018108(peptidyl-tyrosine phosphorylation);GO:0005886(plasma membrane);GO:0005089(Rho guanyl-nucleotide exchange factor activity);GO:0035023(regulation of Rho protein signal transduction);GO:0005515(protein binding);GO:0005096(GTPase activator activity);GO:0030054(cell junction);GO:0045202(synapse);GO:0045211(postsynaptic membrane);GO:0005085(guanyl-nucleotide exchange factor activity);GO:0043547(positive regulation of GTPase activity);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0051056(regulation of small GTPase mediated signal transduction);GO:0014069(postsynaptic density);GO:0043234(protein complex);GO:0004713(protein tyrosine kinase activity);GO:0019899(enzyme binding);GO:0002692(negative regulation of cellular extravasation);GO:0003014(renal system process);GO:0007420(brain development);GO:0030036(actin cytoskeleton organization);GO:0030336(negative regulation of cell migration);GO:0032496(response to lipopolysaccharide);GO:0042472(inner ear morphogenesis);GO:0043114(regulation of vascular permeability);GO:0043314(negative regulation of neutrophil degranulation);GO:0046777(protein autophosphorylation);GO:0048008(platelet-derived growth factor receptor signaling pathway);GO:0048872(homeostasis of number of cells);GO:0050728(negative regulation of inflammatory response);GO:0050766(positive regulation of phagocytosis);GO:0050885(neuromuscular process controlling balance);GO:0051171(regulation of nitrogen compound metabolic process);GO:0051726(regulation of cell cycle);GO:0060216(definitive hemopoiesis);GO:0060268(negative regulation of respiratory burst);GO:0060313(negative regulation of blood vessel remodeling);GO:0065002(intracellular protein transmembrane transport);GO:0071222(cellular response to lipopolysaccharide);GO:2000378(negative regulation of reactive oxygen species metabolic process);GO:0005737(cytoplasm);GO:0005622(intracellular);GO:0005622(intracellular)","05200(Pathways in cancer);05220(Chronic myeloid leukemia);05220(Chronic myeloid leukemia)","K08878","EC:2.7.11.1","BCR, RhoGEF and GTPase activating protein [Source:HGNC Symbol;Acc:HGNC:1014]",{"v":3.33228185527484,"d":"3.33"},{"v":2.91484798813464,"d":"2.91"},{"v":1.14320948085095,"d":"1.14"},{"v":0.193089786136931,"d":"0.19"},{"v":0.738791648440205,"d":"0.74"},1,"up","no"]
["MSTRG.14006","PARP12","ENST00000496624;ENST00000488726;ENST00000473341;ENST00000263549;ENST00000491598;ENST00000467638;ENST00000466597;ENST00000489809;ENST00000489383;ENST00000470515;ENST00000484111;ENST00000493262","GO:0046872(metal ion binding);GO:0016740(transferase activity);GO:0016757(transferase activity, transferring glycosyl groups);GO:0003950(NAD+ ADP-ribosyltransferase activity);GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005634(nucleus)","NA","NA","NA","poly(ADP-ribose) polymerase family member 12 [Source:HGNC Symbol;Acc:HGNC:21919]",{"v":5.48265868416865,"d":"5.48"},{"v":4.80036813428799,"d":"4.80"},{"v":1.14213296372151,"d":"1.14"},{"v":0.191730614742173,"d":"0.19"},{"v":0.74061514482064,"d":"0.74"},1,"up","no"]
["ENSG00000163629","PTPN13","ENST00000436978;ENST00000427191;ENST00000511105","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016787(hydrolase activity);GO:0004725(protein tyrosine phosphatase activity);GO:0016791(phosphatase activity);GO:0006470(protein dephosphorylation);GO:0016311(dephosphorylation);GO:0005886(plasma membrane);GO:0004721(phosphoprotein phosphatase activity);GO:0005856(cytoskeleton);GO:0042995(cell projection);GO:0005515(protein binding);GO:0030027(lamellipodium);GO:0070062(extracellular exosome);GO:0035335(peptidyl-tyrosine dephosphorylation);GO:0006661(phosphatidylinositol biosynthetic process);GO:0014066(regulation of phosphatidylinositol 3-kinase signaling);GO:0036312(phosphatidylinositol 3-kinase regulatory subunit binding);GO:0043005(neuron projection);GO:0044297(cell body);GO:0044297(cell body)","04210(Apoptosis);04210(Apoptosis)","K02374","NA","protein tyrosine phosphatase, non-receptor type 13 [Source:HGNC Symbol;Acc:HGNC:9646]",{"v":0.202897680497051,"d":"0.20"},{"v":0.243730563395114,"d":"0.24"},{"v":0.832467121360285,"d":"0.83"},{"v":-0.264534801426785,"d":"-0.26"},{"v":0.741401106097768,"d":"0.74"},1,"down","no"]
["MSTRG.5151","ICE2","ENST00000261520;ENST00000561114;ENST00000561328;ENST00000560406;ENST00000558121;ENST00000561144;ENST00000561124;ENST00000560072;ENST00000560668;ENST00000558654;ENST00000558512;ENST00000560895;ENST00000561446;ENST00000558451;ENST00000558181","GO:0005634(nucleus);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0016604(nuclear body);GO:0008023(transcription elongation factor complex);GO:0005515(protein binding);GO:0042795(snRNA transcription from RNA polymerase II promoter);GO:0015030(Cajal body);GO:0035327(transcriptionally active chromatin);GO:0045945(positive regulation of transcription from RNA polymerase III promoter);GO:0042796(snRNA transcription from RNA polymerase III promoter);GO:0035363(histone locus body);GO:0035363(histone locus body)","NA","NA","NA","interactor of little elongation complex ELL subunit 2 [Source:HGNC Symbol;Acc:HGNC:29885]",{"v":0.570035482698314,"d":"0.57"},{"v":0.677381591817614,"d":"0.68"},{"v":0.841527861967346,"d":"0.84"},{"v":-0.248917056657526,"d":"-0.25"},{"v":0.741861297970594,"d":"0.74"},1,"down","no"]
["MSTRG.6971","HOXB3;HOXB4;HOXB6","ENST00000470495;ENST00000332503;ENST00000472863;ENST00000478644;ENST00000311626;ENST00000489475;ENST00000464266;ENST00000484302;ENST00000460160;ENST00000465120","GO:0005634(nucleus);GO:0006355(regulation of transcription, DNA-templated);GO:0006366(transcription from RNA polymerase II promoter);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0043565(sequence-specific DNA binding);GO:0007275(multicellular organism development);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0001525(angiogenesis);GO:0001077(transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0000979(RNA polymerase II core promoter sequence-specific DNA binding);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0002244(hematopoietic progenitor cell differentiation);GO:0009952(anterior/posterior pattern specification);GO:0021546(rhombomere development);GO:0021615(glossopharyngeal nerve morphogenesis);GO:0030878(thyroid gland development);GO:0048704(embryonic skeletal system morphogenesis);GO:0050767(regulation of neurogenesis);GO:0051216(cartilage development);GO:0060216(definitive hemopoiesis);GO:0060324(face development);GO:0005813(centrosome);GO:0060218(hematopoietic stem cell differentiation);GO:0002011(morphogenesis of an epithelial sheet);GO:0008283(cell proliferation);GO:0030097(hemopoiesis);GO:0048103(somatic stem cell division);GO:0048536(spleen development);GO:0048539(bone marrow development);GO:0048705(skeletal system morphogenesis);GO:2000738(positive regulation of stem cell differentiation);GO:0003723(RNA binding);GO:0005515(protein binding);GO:0034101(erythrocyte homeostasis);GO:0048706(embryonic skeletal system development);GO:0060324(face development)","NA","NA","NA","homeobox B3 [Source:HGNC Symbol;Acc:HGNC:5114];homeobox B4 [Source:HGNC Symbol;Acc:HGNC:5115];homeobox B6 [Source:HGNC Symbol;Acc:HGNC:5117]",{"v":0.259228932218825,"d":"0.26"},{"v":0.227056022246796,"d":"0.23"},{"v":1.14169591122784,"d":"1.14"},{"v":0.191178442484576,"d":"0.19"},{"v":0.742982381940217,"d":"0.74"},1,"up","no"]
["ENSG00000130349","C6orf203","ENST00000311381;ENST00000625458;ENST00000405204;ENST00000489790","GO:0005739(mitochondrion);GO:0005739(mitochondrion)","NA","NA","NA","chromosome 6 open reading frame 203 [Source:HGNC Symbol;Acc:HGNC:17971]",{"v":1.71688486935167,"d":"1.72"},{"v":1.4927457259332,"d":"1.49"},{"v":1.15015225937314,"d":"1.15"},{"v":0.20182486056283,"d":"0.20"},{"v":0.743393335978442,"d":"0.74"},1,"up","no"]
["ENSG00000189079","ARID2","ENST00000334344;ENST00000479608;ENST00000457135;ENST00000422737;ENST00000477947;ENST00000480128;ENST00000426776","GO:0008285(negative regulation of cell proliferation);GO:0030336(negative regulation of cell migration);GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0005654(nucleoplasm);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0016569(covalent chromatin modification);GO:0003677(DNA binding);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0006337(nucleosome disassembly);GO:0003007(heart morphogenesis);GO:0042592(homeostatic process);GO:0048568(embryonic organ development);GO:0060038(cardiac muscle cell proliferation);GO:0060982(coronary artery morphogenesis);GO:0072358(cardiovascular system development);GO:0090544(BAF-type complex);GO:0090544(BAF-type complex)","05225(Hepatocellular carcinoma);05225(Hepatocellular carcinoma)","K11765","NA","AT-rich interaction domain 2 [Source:HGNC Symbol;Acc:HGNC:18037]",{"v":3.33581577834584,"d":"3.34"},{"v":2.93062642665127,"d":"2.93"},{"v":1.13826032141448,"d":"1.14"},{"v":0.186830541356648,"d":"0.19"},{"v":0.745273785706562,"d":"0.75"},1,"up","no"]
["MSTRG.1441","RNF187","ENST00000639044;ENST00000305943;ENST00000482739","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0016740(transferase activity);GO:0016567(protein ubiquitination);GO:0045893(positive regulation of transcription, DNA-templated);GO:0005515(protein binding);GO:0008284(positive regulation of cell proliferation);GO:0004842(ubiquitin-protein transferase activity);GO:0043161(proteasome-mediated ubiquitin-dependent protein catabolic process);GO:0070936(protein K48-linked ubiquitination);GO:0051865(protein autoubiquitination);GO:0051865(protein autoubiquitination)","NA","NA","NA","ring finger protein 187 [Source:HGNC Symbol;Acc:HGNC:27146]",{"v":11.4239570898021,"d":"11.42"},{"v":10.042073725723,"d":"10.04"},{"v":1.13760936255022,"d":"1.14"},{"v":0.186005243530933,"d":"0.19"},{"v":0.745739857255625,"d":"0.75"},1,"up","no"]
["MSTRG.11506","ZBTB49","ENST00000503703;ENST00000337872;ENST00000515012;ENST00000511458","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0015630(microtubule cytoskeleton);GO:0005515(protein binding);GO:0007049(cell cycle);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0008285(negative regulation of cell proliferation);GO:0007050(cell cycle arrest);GO:0043565(sequence-specific DNA binding);GO:0008134(transcription factor binding);GO:0001223(transcription coactivator binding);GO:0001223(transcription coactivator binding)","NA","NA","NA","zinc finger and BTB domain containing 49 [Source:HGNC Symbol;Acc:HGNC:19883]",{"v":1.87084352647975,"d":"1.87"},{"v":2.214975830045,"d":"2.21"},{"v":0.844633833517606,"d":"0.84"},{"v":-0.243602056521019,"d":"-0.24"},{"v":0.746974215582472,"d":"0.75"},1,"down","no"]
["MSTRG.12704","MRS2","ENST00000378386;ENST00000483634;ENST00000274747;ENST00000443868;ENST00000378353","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005743(mitochondrial inner membrane);GO:0005739(mitochondrion);GO:0006811(ion transport);GO:0055085(transmembrane transport);GO:0015095(magnesium ion transmembrane transporter activity);GO:1990614(mitochondrial magnesium ion transmembrane transport);GO:0006089(lactate metabolic process);GO:0006089(lactate metabolic process)","NA","NA","NA","MRS2, magnesium transporter [Source:HGNC Symbol;Acc:HGNC:13785]",{"v":2.26889710500682,"d":"2.27"},{"v":1.99588825852328,"d":"2.00"},{"v":1.13678563682996,"d":"1.14"},{"v":0.184960231504467,"d":"0.18"},{"v":0.749064595776455,"d":"0.75"},1,"up","no"]
["MSTRG.2394","SERPING1","ENST00000531133;ENST00000403558;ENST00000378323;ENST00000528996;ENST00000531605;ENST00000531797;ENST00000530113;ENST00000278407","GO:0005615(extracellular space);GO:0004867(serine-type endopeptidase inhibitor activity);GO:0010951(negative regulation of endopeptidase activity);GO:0030193(regulation of blood coagulation);GO:0045916(negative regulation of complement activation);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0002376(immune system process);GO:0045087(innate immune response);GO:0030449(regulation of complement activation);GO:0030414(peptidase inhibitor activity);GO:0010466(negative regulation of peptidase activity);GO:0070062(extracellular exosome);GO:0072562(blood microparticle);GO:0007568(aging);GO:0006958(complement activation, classical pathway);GO:0002576(platelet degranulation);GO:0007596(blood coagulation);GO:0007599(hemostasis);GO:0031093(platelet alpha granule lumen);GO:0008015(blood circulation);GO:0007597(blood coagulation, intrinsic pathway);GO:0042730(fibrinolysis);GO:0001869(negative regulation of complement activation, lectin pathway);GO:0001869(negative regulation of complement activation, lectin pathway)","04610(Complement and coagulation cascades);05133(Pertussis);05133(Pertussis)","K04001","NA","serpin family G member 1 [Source:HGNC Symbol;Acc:HGNC:1228]",{"v":4.52402784929226,"d":"4.52"},{"v":3.9798209170136,"d":"3.98"},{"v":1.13674156290606,"d":"1.14"},{"v":0.184904296188226,"d":"0.18"},{"v":0.749155202385754,"d":"0.75"},1,"up","no"]
["MSTRG.15138","MT-ATP6","MSTRG.15138.1","NA","NA","NA","NA",null,{"v":4.581338,"d":"4.58"},{"v":3.972056,"d":"3.97"},{"v":1.15339209719098,"d":"1.15"},{"v":0.205883042487341,"d":"0.21"},{"v":0.75078399096749,"d":"0.75"},1,"up","no"]
["MSTRG.11255","GYG1","ENST00000484197;ENST00000296048;ENST00000479119;ENST00000497528;ENST00000478067;ENST00000492285;ENST00000488851;ENST00000473005;ENST00000345003;ENST00000469873;ENST00000461191","GO:0016020(membrane);GO:0046872(metal ion binding);GO:0016740(transferase activity);GO:0005515(protein binding);GO:0016757(transferase activity, transferring glycosyl groups);GO:0005576(extracellular region);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0043312(neutrophil degranulation);GO:0005978(glycogen biosynthetic process);GO:0034774(secretory granule lumen);GO:1904813(ficolin-1-rich granule lumen);GO:0043202(lysosomal lumen);GO:0008466(glycogenin glucosyltransferase activity);GO:0102751(-);GO:0005980(glycogen catabolic process);GO:0005980(glycogen catabolic process)","00500(Starch and sucrose metabolism);00500(Starch and sucrose metabolism)","K00750","EC:2.4.1.186","glycogenin 1 [Source:HGNC Symbol;Acc:HGNC:4699]",{"v":4.46215402420963,"d":"4.46"},{"v":5.25104435830248,"d":"5.25"},{"v":0.849765060002678,"d":"0.85"},{"v":-0.234864069660693,"d":"-0.23"},{"v":0.75095643974061,"d":"0.75"},1,"down","no"]
["MSTRG.8488","ACP1","ENST00000272065;ENST00000272067;ENST00000442386;ENST00000480874;ENST00000405233;ENST00000407983;ENST00000453390;ENST00000439645;ENST00000463831;ENST00000413140;ENST00000484464;ENST00000484125;ENST00000405364","GO:0005737(cytoplasm);GO:0016787(hydrolase activity);GO:0004725(protein tyrosine phosphatase activity);GO:0006470(protein dephosphorylation);GO:0035335(peptidyl-tyrosine dephosphorylation);GO:0004721(phosphoprotein phosphatase activity);GO:0003993(acid phosphatase activity);GO:0005515(protein binding);GO:0070062(extracellular exosome);GO:0009898(cytoplasmic side of plasma membrane);GO:0004726(non-membrane spanning protein tyrosine phosphatase activity);GO:0016791(phosphatase activity);GO:0005829(cytosol);GO:0042383(sarcolemma);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016021(integral component of membrane)","00730(Thiamine metabolism);00740(Riboflavin metabolism);04520(Adherens junction);04520(Adherens junction)","K14394","EC:3.1.3.2;EC:3.1.3.48","acid phosphatase 1, soluble [Source:HGNC Symbol;Acc:HGNC:122]",{"v":5.63572952524038,"d":"5.64"},{"v":4.97571816081731,"d":"4.98"},{"v":1.13264645285187,"d":"1.13"},{"v":0.17969760492289,"d":"0.18"},{"v":0.751997980007918,"d":"0.75"},1,"up","no"]
["ENSG00000168067","MAP4K2","ENST00000294066;ENST00000435926;ENST00000467689;ENST00000482314;ENST00000433890;ENST00000470088;ENST00000489952;ENST00000439069;ENST00000468062;ENST00000493428;ENST00000377350;ENST00000424945","GO:0005622(intracellular);GO:0005623(cell);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0000165(MAPK cascade);GO:0016310(phosphorylation);GO:0005794(Golgi apparatus);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0000139(Golgi membrane);GO:0008349(MAP kinase kinase kinase kinase activity);GO:0000185(activation of MAPKKK activity);GO:0006903(vesicle targeting);GO:0002376(immune system process);GO:0045087(innate immune response);GO:0016323(basolateral plasma membrane);GO:0006955(immune response);GO:0042981(regulation of apoptotic process);GO:0007346(regulation of mitotic cell cycle);GO:0035556(intracellular signal transduction);GO:0046330(positive regulation of JNK cascade);GO:0031435(mitogen-activated protein kinase kinase kinase binding);GO:0007254(JNK cascade);GO:0007257(activation of JUN kinase activity);GO:0016021(integral component of membrane);GO:0016021(integral component of membrane)","04010(MAPK signaling pathway);04010(MAPK signaling pathway)","K04414","EC:2.7.11.1","mitogen-activated protein kinase kinase kinase kinase 2 [Source:HGNC Symbol;Acc:HGNC:6864]",{"v":6.67604079539809,"d":"6.68"},{"v":5.89605324277683,"d":"5.90"},{"v":1.13228977427855,"d":"1.13"},{"v":0.1792432182545,"d":"0.18"},{"v":0.753290971459297,"d":"0.75"},1,"up","no"]
["MSTRG.4591","GALC","ENST00000261304;ENST00000555000;ENST00000393568;ENST00000477716;ENST00000622264;ENST00000554916;ENST00000555179;ENST00000393569;ENST00000557520;ENST00000474294;ENST00000544807;ENST00000556261;ENST00000554372;ENST00000556879;ENST00000557316","GO:0004336(galactosylceramidase activity);GO:0006683(galactosylceramide catabolic process);GO:0016787(hydrolase activity);GO:0006629(lipid metabolic process);GO:0016042(lipid catabolic process);GO:0008152(metabolic process);GO:0016798(hydrolase activity, acting on glycosyl bonds);GO:0005764(lysosome);GO:0006665(sphingolipid metabolic process);GO:0005739(mitochondrion);GO:0006687(glycosphingolipid metabolic process);GO:0070062(extracellular exosome);GO:0043202(lysosomal lumen);GO:0043202(lysosomal lumen)","00600(Sphingolipid metabolism);04142(Lysosome);04142(Lysosome)","K01202","EC:3.2.1.46","galactosylceramidase [Source:HGNC Symbol;Acc:HGNC:4115]",{"v":2.35133198564103,"d":"2.35"},{"v":2.76458024395604,"d":"2.76"},{"v":0.850520432814906,"d":"0.85"},{"v":-0.233582199425931,"d":"-0.23"},{"v":0.754043640364201,"d":"0.75"},1,"down","no"]
["MSTRG.13408","TCP1","ENST00000321394;ENST00000536807;ENST00000537390;ENST00000546023;ENST00000538530;ENST00000546204;ENST00000539948;ENST00000545764;ENST00000467544;ENST00000536607;ENST00000392168","GO:0003723(RNA binding);GO:0005737(cytoplasm);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0006457(protein folding);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0005874(microtubule);GO:0051082(unfolded protein binding);GO:0005815(microtubule organizing center);GO:0061077(chaperone-mediated protein folding);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0007021(tubulin complex assembly);GO:0035722(interleukin-12-mediated signaling pathway);GO:0050821(protein stabilization);GO:0032212(positive regulation of telomere maintenance via telomerase);GO:0051973(positive regulation of telomerase activity);GO:0005813(centrosome);GO:0031625(ubiquitin protein ligase binding);GO:1904851(positive regulation of establishment of protein localization to telomere);GO:1904874(positive regulation of telomerase RNA localization to Cajal body);GO:0044183(protein binding involved in protein folding);GO:0006458('de novo' protein folding);GO:0007339(binding of sperm to zona pellucida);GO:0044053(translocation of peptides or proteins into host cell cytoplasm);GO:0090666(scaRNA localization to Cajal body);GO:1901998(toxin transport);GO:1904871(positive regulation of protein localization to Cajal body);GO:2000109(regulation of macrophage apoptotic process);GO:0000242(pericentriolar material);GO:0000792(heterochromatin);GO:0001669(acrosomal vesicle);GO:0002199(zona pellucida receptor complex);GO:0005720(nuclear heterochromatin);GO:0005794(Golgi apparatus);GO:0005832(chaperonin-containing T-complex);GO:0043209(myelin sheath);GO:0044297(cell body);GO:0044297(cell body)","NA","NA","NA","t-complex 1 [Source:HGNC Symbol;Acc:HGNC:11655]",{"v":10.4788688922559,"d":"10.48"},{"v":9.2583350899188,"d":"9.26"},{"v":1.13183080872349,"d":"1.13"},{"v":0.178658313595041,"d":"0.18"},{"v":0.75520251779605,"d":"0.76"},1,"up","no"]
["MSTRG.13250","CEP85L","ENST00000419517;ENST00000368491;ENST00000368488;ENST00000392500;ENST00000489276;ENST00000483035","GO:0005737(cytoplasm);GO:0005856(cytoskeleton);GO:0005813(centrosome);GO:0005815(microtubule organizing center);GO:0005815(microtubule organizing center)","NA","NA","NA","centrosomal protein 85 like [Source:HGNC Symbol;Acc:HGNC:21638]",{"v":1.55849635161699,"d":"1.56"},{"v":1.82945968135701,"d":"1.83"},{"v":0.85188887598822,"d":"0.85"},{"v":-0.231262843446283,"d":"-0.23"},{"v":0.755656318693824,"d":"0.76"},1,"down","no"]
["MSTRG.9760","PI3","ENST00000243924","GO:0005576(extracellular region);GO:0010951(negative regulation of endopeptidase activity);GO:0030414(peptidase inhibitor activity);GO:0010466(negative regulation of peptidase activity);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0004867(serine-type endopeptidase inhibitor activity);GO:0019730(antimicrobial humoral response);GO:0005578(proteinaceous extracellular matrix);GO:0004866(endopeptidase inhibitor activity);GO:0070268(cornification);GO:0001533(cornified envelope);GO:0030280(structural constituent of epidermis);GO:0018149(peptide cross-linking);GO:0098773(skin epidermis development);GO:0007620(copulation)","NA","NA","NA","peptidase inhibitor 3 [Source:HGNC Symbol;Acc:HGNC:8947]",{"v":13.560812,"d":"13.56"},{"v":15.896133,"d":"15.90"},{"v":0.85308873548051,"d":"0.85"},{"v":-0.229232281152198,"d":"-0.23"},{"v":0.756854591460606,"d":"0.76"},1,"down","no"]
["ENSG00000117013","KCNQ4","ENST00000347132","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0055085(transmembrane transport);GO:0005216(ion channel activity);GO:0006811(ion transport);GO:0005244(voltage-gated ion channel activity);GO:0005249(voltage-gated potassium channel activity);GO:0005267(potassium channel activity);GO:0006813(potassium ion transport);GO:0034765(regulation of ion transmembrane transport);GO:0071805(potassium ion transmembrane transport);GO:0008076(voltage-gated potassium channel complex);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0007605(sensory perception of sound);GO:0009925(basal plasma membrane);GO:0042472(inner ear morphogenesis)","04725(Cholinergic synapse)","K04929","NA","potassium voltage-gated channel subfamily Q member 4 [Source:HGNC Symbol;Acc:HGNC:6298]",{"v":0.229881092039206,"d":"0.23"},{"v":0.19821795840306,"d":"0.20"},{"v":1.15973897567728,"d":"1.16"},{"v":0.213800132187909,"d":"0.21"},{"v":0.757734287036023,"d":"0.76"},1,"up","no"]
["MSTRG.10937","FAM212A","ENST00000333323","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0071901(negative regulation of protein serine/threonine kinase activity);GO:0070062(extracellular exosome);GO:0019901(protein kinase binding);GO:0030291(protein serine/threonine kinase inhibitor activity);GO:0021915(neural tube development)","NA","NA","NA","family with sequence similarity 212 member A [Source:HGNC Symbol;Acc:HGNC:32480]",{"v":0.857949,"d":"0.86"},{"v":1.023174,"d":"1.02"},{"v":0.838517202352679,"d":"0.84"},{"v":-0.254087713608976,"d":"-0.25"},{"v":0.758675088692227,"d":"0.76"},1,"down","no"]
["ENSG00000074603","DPP8","ENST00000300141;ENST00000341861;ENST00000559233;ENST00000560048;ENST00000560436;ENST00000560194;ENST00000558529;ENST00000321147;ENST00000559526;ENST00000558786;ENST00000395652;ENST00000560665;ENST00000560597;ENST00000358939","GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0016787(hydrolase activity);GO:0008233(peptidase activity);GO:0006508(proteolysis);GO:0006955(immune response);GO:0008236(serine-type peptidase activity);GO:0004177(aminopeptidase activity);GO:0008239(dipeptidyl-peptidase activity);GO:0008239(dipeptidyl-peptidase activity)","NA","NA","NA","dipeptidyl peptidase 8 [Source:HGNC Symbol;Acc:HGNC:16490]",{"v":1.86565764929977,"d":"1.87"},{"v":2.187172730095,"d":"2.19"},{"v":0.852999684765974,"d":"0.85"},{"v":-0.229382886505168,"d":"-0.23"},{"v":0.759532645050652,"d":"0.76"},1,"down","no"]
["MSTRG.14126","GIMAP6","ENST00000618759;ENST00000328902;ENST00000493969;MSTRG.14126.1","GO:0005737(cytoplasm);GO:0005525(GTP binding);GO:0000166(nucleotide binding);GO:0005829(cytosol);GO:0005829(cytosol)","NA","NA","NA","GTPase, IMAP family member 6 [Source:HGNC Symbol;Acc:HGNC:21918]",{"v":25.7968206667483,"d":"25.80"},{"v":22.8749716907621,"d":"22.87"},{"v":1.12773126085075,"d":"1.13"},{"v":0.173423313454907,"d":"0.17"},{"v":0.760152221533984,"d":"0.76"},1,"up","no"]
["MSTRG.10166","UBE2L3","ENST00000342192;ENST00000496722;ENST00000458578","GO:0005737(cytoplasm);GO:0003723(RNA binding);GO:0005634(nucleus);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0005829(cytosol);GO:0016740(transferase activity);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0016567(protein ubiquitination);GO:0005515(protein binding);GO:0006511(ubiquitin-dependent protein catabolic process);GO:0003713(transcription coactivator activity);GO:0005654(nucleoplasm);GO:0070062(extracellular exosome);GO:0061631(ubiquitin conjugating enzyme activity);GO:0008283(cell proliferation);GO:0031625(ubiquitin protein ligase binding);GO:0019899(enzyme binding);GO:0004842(ubiquitin-protein transferase activity);GO:0006464(cellular protein modification process);GO:0070979(protein K11-linked ubiquitination);GO:0000151(ubiquitin ligase complex);GO:1903955(positive regulation of protein targeting to mitochondrion);GO:0000209(protein polyubiquitination);GO:0031398(positive regulation of protein ubiquitination);GO:0071383(cellular response to steroid hormone stimulus);GO:0044770(cell cycle phase transition);GO:0071385(cellular response to glucocorticoid stimulus);GO:0097027(ubiquitin-protein transferase activator activity);GO:0051443(positive regulation of ubiquitin-protein transferase activity);GO:0051443(positive regulation of ubiquitin-protein transferase activity)","04120(Ubiquitin mediated proteolysis);05012(Parkinson's disease);05012(Parkinson's disease)","K04552","EC:2.3.2.23","ubiquitin conjugating enzyme E2 L3 [Source:HGNC Symbol;Acc:HGNC:12488]",{"v":11.6310231188119,"d":"11.63"},{"v":13.6020228196978,"d":"13.60"},{"v":0.855095104087637,"d":"0.86"},{"v":-0.22584320873064,"d":"-0.23"},{"v":0.760773331785782,"d":"0.76"},1,"down","no"]
["MSTRG.3265","KRAS","ENST00000311936;ENST00000556131;ENST00000256078","GO:0010628(positive regulation of gene expression);GO:0001934(positive regulation of protein phosphorylation);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005525(GTP binding);GO:0000166(nucleotide binding);GO:0007165(signal transduction);GO:0003924(GTPase activity);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0005925(focal adhesion);GO:0038095(Fc-epsilon receptor signaling pathway);GO:0050900(leukocyte migration);GO:0031234(extrinsic component of cytoplasmic side of plasma membrane);GO:0000165(MAPK cascade);GO:0002223(stimulatory C-type lectin receptor signaling pathway);GO:0008284(positive regulation of cell proliferation);GO:0031647(regulation of protein stability);GO:0032403(protein complex binding);GO:0007411(axon guidance);GO:0038128(ERBB2 signaling pathway);GO:0007173(epidermal growth factor receptor signaling pathway);GO:0007265(Ras protein signal transduction);GO:0019002(GMP binding);GO:0019003(GDP binding);GO:0030275(LRR domain binding);GO:0001889(liver development);GO:0007565(female pregnancy);GO:0008542(visual learning);GO:0019221(cytokine-mediated signaling pathway);GO:0021897(forebrain astrocyte development);GO:0030036(actin cytoskeleton organization);GO:0032228(regulation of synaptic transmission, GABAergic);GO:0035022(positive regulation of Rac protein signal transduction);GO:0035900(response to isolation stress);GO:0038002(endocrine signaling);GO:0043406(positive regulation of MAP kinase activity);GO:0043524(negative regulation of neuron apoptotic process);GO:0045596(negative regulation of cell differentiation);GO:0048169(regulation of long-term neuronal synaptic plasticity);GO:0048873(homeostasis of number of cells within a tissue);GO:0051000(positive regulation of nitric-oxide synthase activity);GO:0051092(positive regulation of NF-kappaB transcription factor activity);GO:0051146(striated muscle cell differentiation);GO:0051384(response to glucocorticoid);GO:0051385(response to mineralocorticoid);GO:0060441(epithelial tube branching involved in lung morphogenesis);GO:2000774(positive regulation of cellular senescence);GO:0005739(mitochondrion);GO:0045121(membrane raft);GO:0045121(membrane raft)","04014(Ras signaling pathway);04015(Rap1 signaling pathway);04010(MAPK signaling pathway);04012(ErbB signaling pathway);04370(VEGF signaling pathway);04371(Apelin signaling pathway);04068(FoxO signaling pathway);04072(Phospholipase D signaling pathway);04071(Sphingolipid signaling pathway);04151(PI3K-Akt signaling pathway);04150(mTOR signaling pathway);04140(Autophagy - animal);04137(Mitophagy - animal);04210(Apoptosis);04218(Cellular senescence);04540(Gap junction);04550(Signaling pathways regulating pluripotency of stem cells);04810(Regulation of actin cytoskeleton);04650(Natural killer cell mediated cytotoxicity);04660(T cell receptor signaling pathway);04662(B cell receptor signaling pathway);04664(Fc epsilon RI signaling pathway);04062(Chemokine signaling pathway);04910(Insulin signaling pathway);04912(GnRH signaling pathway);04915(Estrogen signaling pathway);04914(Progesterone-mediated oocyte maturation);04917(Prolactin signaling pathway);04921(Oxytocin signaling pathway);04926(Relaxin signaling pathway);04919(Thyroid hormone signaling pathway);04916(Melanogenesis);04960(Aldosterone-regulated sodium reabsorption);04725(Cholinergic synapse);04726(Serotonergic synapse);04720(Long-term potentiation);04730(Long-term depression);04722(Neurotrophin signaling pathway);04360(Axon guidance);04211(Longevity regulating pathway - mammal);04213(Longevity regulating pathway - multiple species);05200(Pathways in cancer);05230(Central carbon metabolism in cancer);05231(Choline metabolism in cancer);05206(MicroRNAs in cancer);05205(Proteoglycans in cancer);05203(Viral carcinogenesis);05210(Colorectal cancer);05212(Pancreatic cancer);05225(Hepatocellular carcinoma);05226(Gastric cancer);05214(Glioma);05216(Thyroid cancer);05221(Acute myeloid leukemia);05220(Chronic myeloid leukemia);05218(Melanoma);05211(Renal cell carcinoma);05219(Bladder cancer);05215(Prostate cancer);05213(Endometrial cancer);05224(Breast cancer);05223(Non-small cell lung cancer);05034(Alcoholism);04933(AGE-RAGE signaling pathway in diabetic complications);05166(HTLV-I infection);05161(Hepatitis B);05160(Hepatitis C);05167(Kaposi's sarcoma-associated herpesvirus infection);05165(Human papillomavirus infection);01521(EGFR tyrosine kinase inhibitor resistance);01522(Endocrine resistance);01522(Endocrine resistance)","K07827","NA","KRAS proto-oncogene, GTPase [Source:HGNC Symbol;Acc:HGNC:6407]",{"v":3.40415052519858,"d":"3.40"},{"v":3.98125985812106,"d":"3.98"},{"v":0.855043540615597,"d":"0.86"},{"v":-0.225930207952201,"d":"-0.23"},{"v":0.761182090569066,"d":"0.76"},1,"down","no"]
["MSTRG.7668","HMG20B","ENST00000453933;ENST00000488973;ENST00000435022;ENST00000333651;ENST00000493191;ENST00000585900;ENST00000461099;ENST00000585741;ENST00000486028;ENST00000487894;ENST00000483417;ENST00000262949;ENST00000464304","GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0003677(DNA binding);GO:0016604(nuclear body);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0016569(covalent chromatin modification);GO:0016575(histone deacetylation);GO:0005694(chromosome);GO:0005515(protein binding);GO:0007049(cell cycle);GO:0004407(histone deacetylase activity);GO:0007596(blood coagulation);GO:0046982(protein heterodimerization activity);GO:0033234(negative regulation of protein sumoylation);GO:0035914(skeletal muscle cell differentiation);GO:0045666(positive regulation of neuron differentiation);GO:0045666(positive regulation of neuron differentiation)","NA","NA","NA","high mobility group 20B [Source:HGNC Symbol;Acc:HGNC:5002]",{"v":4.79976555224268,"d":"4.80"},{"v":5.61285637879181,"d":"5.61"},{"v":0.855137781607704,"d":"0.86"},{"v":-0.225771206084584,"d":"-0.23"},{"v":0.762456977995074,"d":"0.76"},1,"down","no"]
["MSTRG.8458","ZNF551;ZNF776","ENST00000282296;ENST00000317178;ENST00000431353;ENST00000596085;ENST00000601064;ENST00000473585;ENST00000451849;ENST00000599402;ENST00000489376","GO:0003676(nucleic acid binding);GO:0046872(metal ion binding);GO:0006355(regulation of transcription, DNA-templated);GO:0005622(intracellular);GO:0005634(nucleus);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0005622(intracellular)","NA","NA","NA","zinc finger protein 551 [Source:HGNC Symbol;Acc:HGNC:25108];zinc finger protein 776 [Source:HGNC Symbol;Acc:HGNC:26765]",{"v":1.82334755812813,"d":"1.82"},{"v":2.12936119856764,"d":"2.13"},{"v":0.856288524161445,"d":"0.86"},{"v":-0.223831104053645,"d":"-0.22"},{"v":0.7635683237076,"d":"0.76"},1,"down","no"]
["MSTRG.968","MRPL9;AL589765.4","ENST00000368830;ENST00000478926;ENST00000462783;ENST00000512280;ENST00000467306;ENST00000461182;ENST00000468006;ENST00000486707;ENST00000481777;ENST00000368829","GO:0003723(RNA binding);GO:0006412(translation);GO:0005739(mitochondrion);GO:0030529(intracellular ribonucleoprotein complex);GO:0005622(intracellular);GO:0003735(structural constituent of ribosome);GO:0005840(ribosome);GO:0005515(protein binding);GO:0005743(mitochondrial inner membrane);GO:0070125(mitochondrial translational elongation);GO:0070126(mitochondrial translational termination);GO:0005761(mitochondrial ribosome);GO:0005762(mitochondrial large ribosomal subunit);GO:0005762(mitochondrial large ribosomal subunit)","03010(Ribosome);03010(Ribosome)","K02939","NA","mitochondrial ribosomal protein L9 [Source:HGNC Symbol;Acc:HGNC:14277]",{"v":7.01934493063584,"d":"7.02"},{"v":6.2228488371869,"d":"6.22"},{"v":1.12799541083003,"d":"1.13"},{"v":0.173761198245378,"d":"0.17"},{"v":0.763936393525031,"d":"0.76"},1,"up","no"]
["MSTRG.10710","RFTN1","ENST00000334133;ENST00000470458;ENST00000451036;ENST00000483671;ENST00000453536;ENST00000607320;ENST00000441460;ENST00000431547;ENST00000432519;ENST00000484752","GO:0016020(membrane);GO:0005886(plasma membrane);GO:0045121(membrane raft);GO:0070062(extracellular exosome);GO:0043234(protein complex);GO:0005737(cytoplasm);GO:0050852(T cell receptor signaling pathway);GO:0050853(B cell receptor signaling pathway);GO:0043330(response to exogenous dsRNA);GO:0003725(double-stranded RNA binding);GO:0005768(endosome);GO:0001765(membrane raft assembly);GO:1903044(protein localization to membrane raft);GO:0040007(growth);GO:0002457(T cell antigen processing and presentation);GO:0032596(protein transport into membrane raft);GO:0032620(interleukin-17 production);GO:0033227(dsRNA transport);GO:0034138(toll-like receptor 3 signaling pathway);GO:0034138(toll-like receptor 3 signaling pathway)","NA","NA","NA","raftlin, lipid raft linker 1 [Source:HGNC Symbol;Acc:HGNC:30278]",{"v":7.33377142294807,"d":"7.33"},{"v":6.52392470100503,"d":"6.52"},{"v":1.12413489717597,"d":"1.12"},{"v":0.168815170620514,"d":"0.17"},{"v":0.764942036901944,"d":"0.76"},1,"up","no"]
["MSTRG.10395","EIF4ENIF1","ENST00000330125;ENST00000475437;ENST00000441289;ENST00000487671;ENST00000495101;ENST00000344710;ENST00000397523;ENST00000397518;ENST00000418321;ENST00000397525;ENST00000445424","GO:0003723(RNA binding);GO:0006810(transport);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016607(nuclear speck);GO:0016020(membrane);GO:0015031(protein transport);GO:0043231(intracellular membrane-bounded organelle);GO:0005515(protein binding);GO:0016605(PML body);GO:0008565(protein transporter activity);GO:0003743(translation initiation factor activity);GO:0006413(translational initiation);GO:0003729(mRNA binding);GO:0017148(negative regulation of translation);GO:0019827(stem cell population maintenance);GO:0045665(negative regulation of neuron differentiation);GO:0000932(P-body);GO:0005829(cytosol);GO:0005829(cytosol)","NA","NA","NA","eukaryotic translation initiation factor 4E nuclear import factor 1 [Source:HGNC Symbol;Acc:HGNC:16687]",{"v":3.15459463297173,"d":"3.15"},{"v":2.80213317998028,"d":"2.80"},{"v":1.12578326237653,"d":"1.13"},{"v":0.170929104156993,"d":"0.17"},{"v":0.7655717474553,"d":"0.77"},1,"up","no"]
["ENSG00000177054","ZDHHC13","ENST00000446113;ENST00000525490;ENST00000399351;ENST00000524744;ENST00000532812;ENST00000530100;ENST00000532026","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016740(transferase activity);GO:0005794(Golgi apparatus);GO:0016746(transferase activity, transferring acyl groups);GO:0019706(protein-cysteine S-palmitoyltransferase activity);GO:0005783(endoplasmic reticulum);GO:0004871(signal transducer activity);GO:0000139(Golgi membrane);GO:0015095(magnesium ion transmembrane transporter activity);GO:1903830(magnesium ion transmembrane transport);GO:0030659(cytoplasmic vesicle membrane);GO:0031410(cytoplasmic vesicle);GO:0007165(signal transduction);GO:0016409(palmitoyltransferase activity);GO:0043123(positive regulation of I-kappaB kinase/NF-kappaB signaling);GO:0030660(Golgi-associated vesicle membrane);GO:0030660(Golgi-associated vesicle membrane)","NA","NA","NA","zinc finger DHHC-type containing 13 [Source:HGNC Symbol;Acc:HGNC:18413]",{"v":0.546548299239984,"d":"0.55"},{"v":0.640366799304393,"d":"0.64"},{"v":0.85349256056635,"d":"0.85"},{"v":-0.228549516772967,"d":"-0.23"},{"v":0.766695885809592,"d":"0.77"},1,"down","no"]
["ENSG00000037280","FLT4","ENST00000261937;ENST00000510000;ENST00000393347;ENST00000502603;ENST00000424276;ENST00000507059;ENST00000514810","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0004713(protein tyrosine kinase activity);GO:0007169(transmembrane receptor protein tyrosine kinase signaling pathway);GO:0005887(integral component of plasma membrane);GO:0042803(protein homodimerization activity);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0004714(transmembrane receptor protein tyrosine kinase activity);GO:0005021(vascular endothelial growth factor-activated receptor activity);GO:0048010(vascular endothelial growth factor receptor signaling pathway);GO:0002040(sprouting angiogenesis);GO:0001934(positive regulation of protein phosphorylation);GO:0008284(positive regulation of cell proliferation);GO:0043066(negative regulation of apoptotic process);GO:0070374(positive regulation of ERK1 and ERK2 cascade);GO:0019903(protein phosphatase binding);GO:0046777(protein autophosphorylation);GO:0001525(angiogenesis);GO:0019838(growth factor binding);GO:0010595(positive regulation of endothelial cell migration);GO:0035924(cellular response to vascular endothelial growth factor stimulus);GO:0043235(receptor complex);GO:0046330(positive regulation of JNK cascade);GO:0043410(positive regulation of MAPK cascade);GO:0048514(blood vessel morphogenesis);GO:0001938(positive regulation of endothelial cell proliferation);GO:0090037(positive regulation of protein kinase C signaling);GO:0018108(peptidyl-tyrosine phosphorylation);GO:0001944(vasculature development);GO:0060312(regulation of blood vessel remodeling);GO:0010575(positive regulation of vascular endothelial growth factor production);GO:0001946(lymphangiogenesis);GO:0036328(VEGF-C-activated receptor activity);GO:0001945(lymph vessel development);GO:0003016(respiratory system process);GO:0007585(respiratory gaseous exchange);GO:0038084(vascular endothelial growth factor signaling pathway);GO:0048286(lung alveolus development);GO:0048286(lung alveolus development)","04014(Ras signaling pathway);04015(Rap1 signaling pathway);04010(MAPK signaling pathway);04151(PI3K-Akt signaling pathway);04060(Cytokine-cytokine receptor interaction);04510(Focal adhesion);05200(Pathways in cancer);05224(Breast cancer);05224(Breast cancer)","K05097","EC:2.7.10.1","fms related tyrosine kinase 4 [Source:HGNC Symbol;Acc:HGNC:3767]",{"v":0.235811541798464,"d":"0.24"},{"v":0.279733029145956,"d":"0.28"},{"v":0.842987839220891,"d":"0.84"},{"v":-0.246416275608805,"d":"-0.25"},{"v":0.768676170682295,"d":"0.77"},1,"down","no"]
["ENSG00000124302","CHST8","ENST00000604556;ENST00000434302;ENST00000262622","GO:0016021(integral component of membrane);GO:0016740(transferase activity);GO:0005794(Golgi apparatus);GO:0000139(Golgi membrane);GO:0008146(sulfotransferase activity);GO:0005975(carbohydrate metabolic process);GO:0016051(carbohydrate biosynthetic process);GO:0016020(membrane);GO:0042446(hormone biosynthetic process);GO:0006790(sulfur compound metabolic process);GO:0007417(central nervous system development);GO:0030166(proteoglycan biosynthetic process);GO:0001537(N-acetylgalactosamine 4-O-sulfotransferase activity);GO:0001537(N-acetylgalactosamine 4-O-sulfotransferase activity)","NA","NA","NA","carbohydrate sulfotransferase 8 [Source:HGNC Symbol;Acc:HGNC:15993]",{"v":0.200759199541284,"d":"0.20"},{"v":0.23340123689384,"d":"0.23"},{"v":0.860146253777554,"d":"0.86"},{"v":-0.217346107560929,"d":"-0.22"},{"v":0.769295663437284,"d":"0.77"},1,"down","no"]
["ENSG00000065717","TLE2","ENST00000262953;ENST00000589291;ENST00000590536;ENST00000589205;ENST00000591529;ENST00000592305;ENST00000590101;ENST00000587893","GO:0005634(nucleus);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0005925(focal adhesion);GO:0005515(protein binding);GO:0016604(nuclear body);GO:0016055(Wnt signaling pathway);GO:0005615(extracellular space);GO:0003714(transcription corepressor activity);GO:0005654(nucleoplasm);GO:0090090(negative regulation of canonical Wnt signaling pathway);GO:0007165(signal transduction);GO:0045892(negative regulation of transcription, DNA-templated);GO:1904837(beta-catenin-TCF complex assembly);GO:0009887(animal organ morphogenesis);GO:0009887(animal organ morphogenesis)","NA","NA","NA","transducin like enhancer of split 2 [Source:HGNC Symbol;Acc:HGNC:11838]",{"v":1.29158889499752,"d":"1.29"},{"v":1.1547949157999,"d":"1.15"},{"v":1.11845737916404,"d":"1.12"},{"v":0.161510280947565,"d":"0.16"},{"v":0.770053783971277,"d":"0.77"},1,"up","no"]
["MSTRG.7465","RNF125;RNF138","ENST00000217740;ENST00000261593;ENST00000257190;ENST00000580863;ENST00000585103;ENST00000580499;ENST00000583814;ENST00000577999;ENST00000583733;ENST00000578914;ENST00000578107;ENST00000580209;ENST00000580519","GO:0016020(membrane);GO:0046872(metal ion binding);GO:0016740(transferase activity);GO:0016567(protein ubiquitination);GO:0005794(Golgi apparatus);GO:0008270(zinc ion binding);GO:0000139(Golgi membrane);GO:0006511(ubiquitin-dependent protein catabolic process);GO:0002376(immune system process);GO:0002250(adaptive immune response);GO:0005515(protein binding);GO:0043231(intracellular membrane-bounded organelle);GO:0032480(negative regulation of type I interferon production);GO:0042787(protein ubiquitination involved in ubiquitin-dependent protein catabolic process);GO:0002039(p53 binding);GO:0061630(ubiquitin protein ligase activity);GO:0000209(protein polyubiquitination);GO:0031624(ubiquitin conjugating enzyme binding);GO:0032436(positive regulation of proteasomal ubiquitin-dependent protein catabolic process);GO:0039536(negative regulation of RIG-I signaling pathway);GO:0034098(VCP-NPL4-UFD1 AAA ATPase complex);GO:0005634(nucleus);GO:0003677(DNA binding);GO:0005694(chromosome);GO:0006281(DNA repair);GO:0006974(cellular response to DNA damage stimulus);GO:0016055(Wnt signaling pathway);GO:1990830(cellular response to leukemia inhibitory factor);GO:0019901(protein kinase binding);GO:0000724(double-strand break repair via homologous recombination);GO:0003697(single-stranded DNA binding);GO:0035861(site of double-strand break);GO:0010792(DNA double-strand break processing involved in repair via single-strand annealing);GO:0010792(DNA double-strand break processing involved in repair via single-strand annealing)","04622(RIG-I-like receptor signaling pathway);04622(RIG-I-like receptor signaling pathway)","K12170","EC:2.3.2.27","ring finger protein 125 [Source:HGNC Symbol;Acc:HGNC:21150];ring finger protein 138 [Source:HGNC Symbol;Acc:HGNC:17765]",{"v":5.59358198893526,"d":"5.59"},{"v":4.99146298155877,"d":"4.99"},{"v":1.12062976518128,"d":"1.12"},{"v":0.164309717785261,"d":"0.16"},{"v":0.771048790643783,"d":"0.77"},1,"up","no"]
["ENSG00000198752","CDC42BPB","ENST00000361246;ENST00000559790;ENST00000558321;ENST00000561271;ENST00000559043;ENST00000560492;ENST00000559245","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0035556(intracellular signal transduction);GO:0005886(plasma membrane);GO:0030036(actin cytoskeleton organization);GO:0000287(magnesium ion binding);GO:0030054(cell junction);GO:0017048(Rho GTPase binding);GO:0016477(cell migration);GO:0031032(actomyosin structure organization);GO:0042641(actomyosin);GO:0031252(cell leading edge);GO:0070062(extracellular exosome);GO:0007165(signal transduction);GO:0005856(cytoskeleton);GO:0005911(cell-cell junction);GO:0007010(cytoskeleton organization);GO:0031532(actin cytoskeleton reorganization);GO:0007163(establishment or maintenance of cell polarity);GO:0005622(intracellular);GO:0005622(intracellular)","NA","NA","NA","CDC42 binding protein kinase beta [Source:HGNC Symbol;Acc:HGNC:1738]",{"v":1.4275018087152,"d":"1.43"},{"v":1.65743236496441,"d":"1.66"},{"v":0.861273038279214,"d":"0.86"},{"v":-0.215457425759391,"d":"-0.22"},{"v":0.773000182049972,"d":"0.77"},1,"down","no"]
["MSTRG.2650","NADSYN1","ENST00000530055;ENST00000530534;ENST00000528509;ENST00000624637;ENST00000319023;ENST00000525200;ENST00000529120;ENST00000527852;ENST00000526039;ENST00000528211;ENST00000527538;ENST00000533612;ENST00000525593;ENST00000531236;ENST00000530831;ENST00000525245;ENST00000533769;ENST00000527963;ENST00000534634;ENST00000524949","GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0005829(cytosol);GO:0016874(ligase activity);GO:0005515(protein binding);GO:0016810(hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds);GO:0006807(nitrogen compound metabolic process);GO:0009435(NAD biosynthetic process);GO:0005737(cytoplasm);GO:0003952(NAD+ synthase (glutamine-hydrolyzing) activity);GO:0019674(NAD metabolic process);GO:0004359(glutaminase activity);GO:0004359(glutaminase activity)","00760(Nicotinate and nicotinamide metabolism);00760(Nicotinate and nicotinamide metabolism)","K01950","EC:6.3.5.1","NAD synthetase 1 [Source:HGNC Symbol;Acc:HGNC:29832]",{"v":2.66987303357314,"d":"2.67"},{"v":2.38437056072065,"d":"2.38"},{"v":1.11973913684214,"d":"1.12"},{"v":0.163162669944447,"d":"0.16"},{"v":0.773173859024764,"d":"0.77"},1,"up","no"]
["MSTRG.14404","RDH10","ENST00000240285;ENST00000518870;ENST00000521013;ENST00000519380","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0004745(retinol dehydrogenase activity);GO:0052650(NADP-retinol dehydrogenase activity);GO:0001656(metanephros development);GO:0001701(in utero embryonic development);GO:0002138(retinoic acid biosynthetic process);GO:0008406(gonad development);GO:0009887(animal organ morphogenesis);GO:0014032(neural crest cell development);GO:0031076(embryonic camera-type eye development);GO:0035115(embryonic forelimb morphogenesis);GO:0042572(retinol metabolic process);GO:0042574(retinal metabolic process);GO:0043583(ear development);GO:0043584(nose development);GO:0048568(embryonic organ development);GO:0048703(embryonic viscerocranium morphogenesis);GO:0060431(primary lung bud formation);GO:0060449(bud elongation involved in lung branching);GO:0044297(cell body);GO:0043231(intracellular membrane-bounded organelle);GO:0031090(organelle membrane);GO:0001523(retinoid metabolic process);GO:0007601(visual perception);GO:0007601(visual perception)","00830(Retinol metabolism);00830(Retinol metabolism)","K11151","EC:1.1.1.-","retinol dehydrogenase 10 [Source:HGNC Symbol;Acc:HGNC:19975]",{"v":0.173574708701372,"d":"0.17"},{"v":0.15185639560233,"d":"0.15"},{"v":1.14301875803714,"d":"1.14"},{"v":0.192849079759829,"d":"0.19"},{"v":0.775019705120292,"d":"0.78"},1,"up","no"]
["ENSG00000118596","SLC16A7","ENST00000261187;ENST00000548444;ENST00000547379;ENST00000549033;ENST00000551877;ENST00000549465;ENST00000546459","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0055085(transmembrane transport);GO:0005887(integral component of plasma membrane);GO:0015293(symporter activity);GO:0005886(plasma membrane);GO:0008028(monocarboxylic acid transmembrane transporter activity);GO:0015718(monocarboxylic acid transport);GO:1901475(pyruvate transmembrane transport);GO:0005477(pyruvate secondary active transmembrane transporter activity);GO:0015129(lactate transmembrane transporter activity);GO:0050833(pyruvate transmembrane transporter activity);GO:0035873(lactate transmembrane transport);GO:0035873(lactate transmembrane transport)","NA","NA","NA","solute carrier family 16 member 7 [Source:HGNC Symbol;Acc:HGNC:10928]",{"v":0.820197590413465,"d":"0.82"},{"v":0.732162356970362,"d":"0.73"},{"v":1.12024004321581,"d":"1.12"},{"v":0.163807903757086,"d":"0.16"},{"v":0.77545635577465,"d":"0.78"},1,"up","no"]
["MSTRG.165","MIIP","ENST00000235332;ENST00000492256;ENST00000460823;ENST00000466860;ENST00000478299;ENST00000498685;ENST00000478749","GO:0005515(protein binding);GO:0030336(negative regulation of cell migration);GO:0010972(negative regulation of G2/M transition of mitotic cell cycle);GO:0010972(negative regulation of G2/M transition of mitotic cell cycle)","NA","NA","NA","migration and invasion inhibitory protein [Source:HGNC Symbol;Acc:HGNC:25715]",{"v":4.04193684367246,"d":"4.04"},{"v":4.69740872208437,"d":"4.70"},{"v":0.860460965355159,"d":"0.86"},{"v":-0.216818348718197,"d":"-0.22"},{"v":0.776326361709139,"d":"0.78"},1,"down","no"]
["ENSG00000101138","CSTF1","ENST00000217109;ENST00000493039;ENST00000452950;ENST00000613138;ENST00000415828;ENST00000498689","GO:0003723(RNA binding);GO:0006397(mRNA processing);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005515(protein binding);GO:0006369(termination of RNA polymerase II transcription);GO:0031124(mRNA 3'-end processing);GO:0000398(mRNA splicing, via spliceosome);GO:0000398(mRNA splicing, via spliceosome)","03015(mRNA surveillance pathway);03015(mRNA surveillance pathway)","K14406","NA","cleavage stimulation factor subunit 1 [Source:HGNC Symbol;Acc:HGNC:2483]",{"v":2.56132379770833,"d":"2.56"},{"v":2.96932135125,"d":"2.97"},{"v":0.862595689291119,"d":"0.86"},{"v":-0.213243588476281,"d":"-0.21"},{"v":0.778258848258379,"d":"0.78"},1,"down","no"]
["MSTRG.158","FBXO6","ENST00000376753;ENST00000474239;ENST00000449067","GO:0005737(cytoplasm);GO:0016567(protein ubiquitination);GO:0005515(protein binding);GO:0006281(DNA repair);GO:0006974(cellular response to DNA damage stimulus);GO:0006986(response to unfolded protein);GO:0005829(cytosol);GO:0000209(protein polyubiquitination);GO:0043687(post-translational protein modification);GO:0030433(ubiquitin-dependent ERAD pathway);GO:0000077(DNA damage checkpoint);GO:0004842(ubiquitin-protein transferase activity);GO:0006508(proteolysis);GO:0019005(SCF ubiquitin ligase complex);GO:0031146(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process);GO:0030246(carbohydrate binding);GO:0061630(ubiquitin protein ligase activity);GO:0006516(glycoprotein catabolic process);GO:0044322(endoplasmic reticulum quality control compartment);GO:0044322(endoplasmic reticulum quality control compartment)","04141(Protein processing in endoplasmic reticulum);04141(Protein processing in endoplasmic reticulum)","K10100","NA","F-box protein 6 [Source:HGNC Symbol;Acc:HGNC:13585]",{"v":3.6825747542794,"d":"3.68"},{"v":3.28704112147985,"d":"3.29"},{"v":1.12033120918837,"d":"1.12"},{"v":0.163925306581423,"d":"0.16"},{"v":0.778672361848292,"d":"0.78"},1,"up","no"]
["ENSG00000196550","FAM72A","ENST00000367128;ENST00000468509;ENST00000607379;ENST00000470041","GO:0005737(cytoplasm);GO:0043231(intracellular membrane-bounded organelle);GO:0005829(cytosol);GO:0005739(mitochondrion);GO:0005515(protein binding);GO:0005515(protein binding)","NA","NA","NA","family with sequence similarity 72 member A [Source:HGNC Symbol;Acc:HGNC:24044]",{"v":0.164229060005287,"d":"0.16"},{"v":0.197899929949775,"d":"0.20"},{"v":0.829859111354747,"d":"0.83"},{"v":-0.269061669997609,"d":"-0.27"},{"v":0.779995008802463,"d":"0.78"},1,"down","no"]
["ENSG00000125877","ITPA","ENST00000380113;ENST00000472295;ENST00000460676;ENST00000461029;ENST00000609835;ENST00000399838;ENST00000455664;ENST00000460550;ENST00000490838","GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0005829(cytosol);GO:0016787(hydrolase activity);GO:0009117(nucleotide metabolic process);GO:0042802(identical protein binding);GO:0004551(nucleotide diphosphatase activity);GO:0035529(NADH pyrophosphatase activity);GO:0035870(dITP diphosphatase activity);GO:0047429(nucleoside-triphosphate diphosphatase activity);GO:0006193(ITP catabolic process);GO:0009143(nucleoside triphosphate catabolic process);GO:0051276(chromosome organization);GO:0006195(purine nucleotide catabolic process);GO:0036220(ITP diphosphatase activity);GO:0036222(XTP diphosphatase activity);GO:0036222(XTP diphosphatase activity)","00230(Purine metabolism);00983(Drug metabolism - other enzymes);00983(Drug metabolism - other enzymes)","K01519","EC:3.6.1.-","inosine triphosphatase [Source:HGNC Symbol;Acc:HGNC:6176]",{"v":3.17380181554804,"d":"3.17"},{"v":2.8456422689522,"d":"2.85"},{"v":1.11532002816245,"d":"1.12"},{"v":0.157457734178237,"d":"0.16"},{"v":0.780474095166892,"d":"0.78"},1,"up","no"]
["MSTRG.12353","KDM3B","ENST00000314358;ENST00000508386;ENST00000504095;ENST00000509468;ENST00000512928;ENST00000510866;ENST00000505756","GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0016569(covalent chromatin modification);GO:0051213(dioxygenase activity);GO:0098869(cellular oxidant detoxification);GO:0005654(nucleoplasm);GO:0000976(transcription regulatory region sequence-specific DNA binding);GO:0032452(histone demethylase activity);GO:0000785(chromatin);GO:0031490(chromatin DNA binding);GO:0032454(histone demethylase activity (H3-K9 specific));GO:0033169(histone H3-K9 demethylation);GO:0016209(antioxidant activity);GO:0072718(response to cisplatin);GO:0072718(response to cisplatin)","NA","NA","NA","lysine demethylase 3B [Source:HGNC Symbol;Acc:HGNC:1337]",{"v":8.17398540233639,"d":"8.17"},{"v":9.44737244052255,"d":"9.45"},{"v":0.865212571410414,"d":"0.87"},{"v":-0.208873467290085,"d":"-0.21"},{"v":0.781396334478705,"d":"0.78"},1,"down","no"]
["ENSG00000100362","PVALB","ENST00000417718;ENST00000467935;ENST00000406910","GO:0046872(metal ion binding);GO:0005509(calcium ion binding);GO:0070062(extracellular exosome);GO:0042803(protein homodimerization activity);GO:0046982(protein heterodimerization activity);GO:0051480(regulation of cytosolic calcium ion concentration);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0030424(axon);GO:0043025(neuronal cell body);GO:0043195(terminal bouton);GO:0043234(protein complex);GO:0043234(protein complex)","NA","NA","NA","parvalbumin [Source:HGNC Symbol;Acc:HGNC:9704]",{"v":1.02961780190476,"d":"1.03"},{"v":1.22262284761905,"d":"1.22"},{"v":0.842138525310442,"d":"0.84"},{"v":-0.247870529837217,"d":"-0.25"},{"v":0.782073739943182,"d":"0.78"},1,"down","no"]
["MSTRG.9677","GSS","ENST00000216951;ENST00000451957","GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0042803(protein homodimerization activity);GO:0016874(ligase activity);GO:0005515(protein binding);GO:0000287(magnesium ion binding);GO:0042802(identical protein binding);GO:0006750(glutathione biosynthetic process);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0004363(glutathione synthase activity);GO:0007399(nervous system development);GO:0006979(response to oxidative stress);GO:0043295(glutathione binding);GO:0006520(cellular amino acid metabolic process);GO:0016594(glycine binding);GO:0042277(peptide binding);GO:0007568(aging);GO:0009410(response to xenobiotic stimulus);GO:0031667(response to nutrient levels);GO:0034612(response to tumor necrosis factor);GO:0043200(response to amino acid);GO:0046686(response to cadmium ion);GO:0046686(response to cadmium ion)","00270(Cysteine and methionine metabolism);00480(Glutathione metabolism);04216(Ferroptosis);04216(Ferroptosis)","K21456","EC:6.3.2.3","glutathione synthetase [Source:HGNC Symbol;Acc:HGNC:4624]",{"v":5.615,"d":"5.62"},{"v":5.03353562851197,"d":"5.03"},{"v":1.11551808001405,"d":"1.12"},{"v":0.157713896580916,"d":"0.16"},{"v":0.783181232802323,"d":"0.78"},1,"up","no"]
["MSTRG.7596","POLR2E","ENST00000612655;ENST00000615234;ENST00000589737;ENST00000586746;ENST00000586215;ENST00000585838;ENST00000619917;ENST00000591709;ENST00000590060;ENST00000586817;ENST00000215587;ENST00000591767;ENST00000592597","GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0003677(DNA binding);GO:0006351(transcription, DNA-templated);GO:0005515(protein binding);GO:0003899(DNA-directed 5'-3' RNA polymerase activity);GO:0005666(DNA-directed RNA polymerase III complex);GO:0005829(cytosol);GO:0006366(transcription from RNA polymerase II promoter);GO:0016032(viral process);GO:0045815(positive regulation of gene expression, epigenetic);GO:0006368(transcription elongation from RNA polymerase II promoter);GO:0006370(7-methylguanosine mRNA capping);GO:0050434(positive regulation of viral transcription);GO:0006367(transcription initiation from RNA polymerase II promoter);GO:0042795(snRNA transcription from RNA polymerase II promoter);GO:0001056(RNA polymerase III activity);GO:0006383(transcription from RNA polymerase III promoter);GO:0032481(positive regulation of type I interferon production);GO:0000398(mRNA splicing, via spliceosome);GO:0001054(RNA polymerase I activity);GO:0006361(transcription initiation from RNA polymerase I promoter);GO:0006362(transcription elongation from RNA polymerase I promoter);GO:0006363(termination of RNA polymerase I transcription);GO:0005736(DNA-directed RNA polymerase I complex);GO:0060964(regulation of gene silencing by miRNA);GO:0006283(transcription-coupled nucleotide-excision repair);GO:0008543(fibroblast growth factor receptor signaling pathway);GO:0016070(RNA metabolic process);GO:0035019(somatic stem cell population maintenance);GO:0005665(DNA-directed RNA polymerase II, core complex);GO:0001055(RNA polymerase II activity);GO:0001055(RNA polymerase II activity)","00230(Purine metabolism);00240(Pyrimidine metabolism);03020(RNA polymerase);04623(Cytosolic DNA-sensing pathway);05016(Huntington's disease);05169(Epstein-Barr virus infection);05169(Epstein-Barr virus infection)","K03013","NA","RNA polymerase II subunit E [Source:HGNC Symbol;Acc:HGNC:9192]",{"v":7.86581296073998,"d":"7.87"},{"v":7.07604479157246,"d":"7.08"},{"v":1.11161152768679,"d":"1.11"},{"v":0.152652700833484,"d":"0.15"},{"v":0.784279736173757,"d":"0.78"},1,"up","no"]
["MSTRG.9568","DDRGK1","ENST00000354488;ENST00000470203;ENST00000496781;ENST00000380201","GO:0005783(endoplasmic reticulum);GO:0005730(nucleolus);GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0051092(positive regulation of NF-kappaB transcription factor activity);GO:0034976(response to endoplasmic reticulum stress);GO:0044389(ubiquitin-like protein ligase binding);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0010628(positive regulation of gene expression);GO:0010629(negative regulation of gene expression);GO:0032436(positive regulation of proteasomal ubiquitin-dependent protein catabolic process);GO:0033146(regulation of intracellular estrogen receptor signaling pathway);GO:1990592(protein K69-linked ufmylation);GO:0005789(endoplasmic reticulum membrane);GO:0043066(negative regulation of apoptotic process);GO:0030335(positive regulation of cell migration);GO:0008284(positive regulation of cell proliferation);GO:1901800(positive regulation of proteasomal protein catabolic process);GO:0001103(RNA polymerase II repressing transcription factor binding);GO:1902808(positive regulation of cell cycle G1/S phase transition);GO:1903721(positive regulation of I-kappaB phosphorylation);GO:1905050(positive regulation of metallopeptidase activity);GO:1905552(positive regulation of protein localization to endoplasmic reticulum);GO:1905636(positive regulation of RNA polymerase II regulatory region sequence-specific DNA binding);GO:1905636(positive regulation of RNA polymerase II regulatory region sequence-specific DNA binding)","NA","NA","NA","DDRGK domain containing 1 [Source:HGNC Symbol;Acc:HGNC:16110]",{"v":7.1646450900655,"d":"7.16"},{"v":6.43574872707424,"d":"6.44"},{"v":1.11325743031652,"d":"1.11"},{"v":0.154787240925236,"d":"0.15"},{"v":0.785447844016755,"d":"0.79"},1,"up","no"]
["MSTRG.3308","ANO6","ENST00000320560;ENST00000426898;ENST00000423947;ENST00000441606;ENST00000550630;ENST00000551667;ENST00000425752","GO:1902304(positive regulation of potassium ion export);GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005829(cytosol);GO:0046983(protein dimerization activity);GO:0005886(plasma membrane);GO:1903959(regulation of anion transmembrane transport);GO:0005244(voltage-gated ion channel activity);GO:0006811(ion transport);GO:0034765(regulation of ion transmembrane transport);GO:0006869(lipid transport);GO:0007596(blood coagulation);GO:0005254(chloride channel activity);GO:0006821(chloride transport);GO:0034707(chloride channel complex);GO:0070588(calcium ion transmembrane transport);GO:1902476(chloride transmembrane transport);GO:0005247(voltage-gated chloride channel activity);GO:0005515(protein binding);GO:0070062(extracellular exosome);GO:0005229(intracellular calcium activated chloride channel activity);GO:0034220(ion transmembrane transport);GO:0061588(calcium activated phospholipid scrambling);GO:0005622(intracellular);GO:0043065(positive regulation of apoptotic process);GO:0043312(neutrophil degranulation);GO:0035579(specific granule membrane);GO:0070821(tertiary granule membrane);GO:0030501(positive regulation of bone mineralization);GO:0035725(sodium ion transmembrane transport);GO:0009986(cell surface);GO:0017121(phospholipid scrambling);GO:0090026(positive regulation of monocyte chemotaxis);GO:2000353(positive regulation of endothelial cell apoptotic process);GO:0006812(cation transport);GO:0032060(bleb assembly);GO:0060100(positive regulation of phagocytosis, engulfment);GO:0046931(pore complex assembly);GO:0045794(negative regulation of cell volume);GO:0005227(calcium activated cation channel activity);GO:0002407(dendritic cell chemotaxis);GO:0002543(activation of blood coagulation via clotting cascade);GO:0034767(positive regulation of ion transmembrane transport);GO:0035590(purinergic nucleotide receptor signaling pathway);GO:0097045(phosphatidylserine exposure on blood platelet);GO:0017128(phospholipid scramblase activity);GO:0042803(protein homodimerization activity);GO:0035630(bone mineralization involved in bone maturation);GO:0061589(calcium activated phosphatidylserine scrambling);GO:0061590(calcium activated phosphatidylcholine scrambling);GO:0061591(calcium activated galactosylceramide scrambling);GO:0061591(calcium activated galactosylceramide scrambling)","NA","NA","NA","anoctamin 6 [Source:HGNC Symbol;Acc:HGNC:25240]",{"v":5.85382431378263,"d":"5.85"},{"v":6.7401986948391,"d":"6.74"},{"v":0.868494324694737,"d":"0.87"},{"v":-0.203411673426088,"d":"-0.20"},{"v":0.787514642992147,"d":"0.79"},1,"down","no"]
["MSTRG.6172","CENPN","ENST00000305850;ENST00000562943;ENST00000393335;ENST00000428963;ENST00000299572","GO:0005634(nucleus);GO:0005694(chromosome);GO:0007059(chromosome segregation);GO:0000775(chromosome, centromeric region);GO:0034508(centromere complex assembly);GO:0000776(kinetochore);GO:0000777(condensed chromosome kinetochore);GO:0000278(mitotic cell cycle);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0034080(CENP-A containing nucleosome assembly);GO:0007062(sister chromatid cohesion);GO:0007062(sister chromatid cohesion)","NA","NA","NA","centromere protein N [Source:HGNC Symbol;Acc:HGNC:30873]",{"v":0.245976045964126,"d":"0.25"},{"v":0.213921772141256,"d":"0.21"},{"v":1.14984110080064,"d":"1.15"},{"v":0.201434505581824,"d":"0.20"},{"v":0.787605849383548,"d":"0.79"},1,"up","no"]
["MSTRG.13816","TSC22D4;C7orf61","ENST00000300181;ENST00000393991;ENST00000493217;MSTRG.13816.4;ENST00000418952;ENST00000456330;ENST00000423266;ENST00000496728;ENST00000332375","GO:0005634(nucleus);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0045892(negative regulation of transcription, DNA-templated);GO:0070236(negative regulation of activation-induced cell death of T cells);GO:0005634(nucleus)","NA","NA","NA","TSC22 domain family member 4 [Source:HGNC Symbol;Acc:HGNC:21696];chromosome 7 open reading frame 61 [Source:HGNC Symbol;Acc:HGNC:22135]",{"v":8.41548417620326,"d":"8.42"},{"v":9.68067024891551,"d":"9.68"},{"v":0.869308008621202,"d":"0.87"},{"v":-0.202060659183738,"d":"-0.20"},{"v":0.78960206709295,"d":"0.79"},1,"down","no"]
["ENSG00000169905","TOR1AIP2","ENST00000367612;ENST00000482587;ENST00000483123;ENST00000474318;ENST00000609928","GO:0005634(nucleus);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0031965(nuclear membrane);GO:0007029(endoplasmic reticulum organization);GO:0032781(positive regulation of ATPase activity);GO:0001671(ATPase activator activity);GO:0051117(ATPase binding);GO:0090435(protein localization to nuclear envelope);GO:0005515(protein binding);GO:0005515(protein binding)","NA","NA","NA","torsin 1A interacting protein 2 [Source:HGNC Symbol;Acc:HGNC:24055]",{"v":0.939048447393516,"d":"0.94"},{"v":0.847500845994914,"d":"0.85"},{"v":1.10802066078309,"d":"1.11"},{"v":0.147984782949744,"d":"0.15"},{"v":0.79008582443279,"d":"0.79"},1,"up","no"]
["MSTRG.8207","CEACAM8","ENST00000244336;ENST00000599005","GO:0016020(membrane);GO:0005886(plasma membrane);GO:0005615(extracellular space);GO:0031225(anchored component of membrane);GO:0050900(leukocyte migration);GO:0005515(protein binding);GO:0070062(extracellular exosome);GO:0005887(integral component of plasma membrane);GO:0043312(neutrophil degranulation);GO:0035579(specific granule membrane);GO:0070821(tertiary granule membrane);GO:0006955(immune response);GO:0035577(azurophil granule membrane);GO:0035577(azurophil granule membrane)","NA","NA","NA","carcinoembryonic antigen related cell adhesion molecule 8 [Source:HGNC Symbol;Acc:HGNC:1820]",{"v":4.73502569384555,"d":"4.74"},{"v":5.43917324852999,"d":"5.44"},{"v":0.870541436628307,"d":"0.87"},{"v":-0.200015124988686,"d":"-0.20"},{"v":0.791012953436024,"d":"0.79"},1,"down","no"]
["MSTRG.10569","KIAA0930","ENST00000488038;ENST00000336156;ENST00000424508;ENST00000391627;ENST00000417906;ENST00000440039;ENST00000474515;ENST00000493003;ENST00000498418;ENST00000483374;ENST00000414854;ENST00000486640;ENST00000251993","NA","NA","NA","NA","KIAA0930 [Source:HGNC Symbol;Acc:HGNC:1314]",{"v":5.70883969737499,"d":"5.71"},{"v":6.55348467142429,"d":"6.55"},{"v":0.871115136999973,"d":"0.87"},{"v":-0.199064679621182,"d":"-0.20"},{"v":0.792285600621695,"d":"0.79"},1,"down","no"]
["MSTRG.13848","LRWD1","ENST00000473880;ENST00000292616;ENST00000464107;ENST00000463739;ENST00000485808;ENST00000476270;ENST00000485417","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005730(nucleolus);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0016569(covalent chromatin modification);GO:0005694(chromosome);GO:0005856(cytoskeleton);GO:0006260(DNA replication);GO:0005815(microtubule organizing center);GO:0000775(chromosome, centromeric region);GO:0000776(kinetochore);GO:0000777(condensed chromosome kinetochore);GO:0006325(chromatin organization);GO:0000781(chromosome, telomeric region);GO:0005515(protein binding);GO:0003682(chromatin binding);GO:0035064(methylated histone binding);GO:0008327(methyl-CpG binding);GO:0005664(nuclear origin of replication recognition complex);GO:0006270(DNA replication initiation);GO:0071169(establishment of protein localization to chromatin);GO:0031933(telomeric heterochromatin);GO:0005721(pericentric heterochromatin);GO:0005721(pericentric heterochromatin)","NA","NA","NA","leucine rich repeats and WD repeat domain containing 1 [Source:HGNC Symbol;Acc:HGNC:21769]",{"v":1.21747203256834,"d":"1.22"},{"v":1.39794910023625,"d":"1.40"},{"v":0.870898684624919,"d":"0.87"},{"v":-0.199423201196394,"d":"-0.20"},{"v":0.792509297695104,"d":"0.79"},1,"down","no"]
["MSTRG.9624","CST3","ENST00000376925;ENST00000398411;ENST00000398409","GO:0005615(extracellular space);GO:0010951(negative regulation of endopeptidase activity);GO:0005576(extracellular region);GO:0004869(cysteine-type endopeptidase inhibitor activity);GO:0030414(peptidase inhibitor activity);GO:0010466(negative regulation of peptidase activity);GO:0042802(identical protein binding);GO:0002020(protease binding);GO:0001654(eye development);GO:0001666(response to hypoxia);GO:0001775(cell activation);GO:0006915(apoptotic process);GO:0006979(response to oxidative stress);GO:0007420(brain development);GO:0007431(salivary gland development);GO:0007566(embryo implantation);GO:0008284(positive regulation of cell proliferation);GO:0008584(male gonad development);GO:0009636(response to toxic substance);GO:0009743(response to carbohydrate);GO:0010035(response to inorganic substance);GO:0014070(response to organic cyclic compound);GO:0031667(response to nutrient levels);GO:0032355(response to estradiol);GO:0034599(cellular response to oxidative stress);GO:0042493(response to drug);GO:0042747(circadian sleep/wake cycle, REM sleep);GO:0043067(regulation of programmed cell death);GO:0045740(positive regulation of DNA replication);GO:0048678(response to axon injury);GO:0060009(Sertoli cell development);GO:0060548(negative regulation of cell death);GO:0070301(cellular response to hydrogen peroxide);GO:0005604(basement membrane);GO:0005737(cytoplasm);GO:0005764(lysosome);GO:0005771(multivesicular body);GO:0005783(endoplasmic reticulum);GO:0030424(axon);GO:0031965(nuclear membrane);GO:0031982(vesicle);GO:0042995(cell projection);GO:0043025(neuronal cell body);GO:0043292(contractile fiber);GO:0048471(perinuclear region of cytoplasm);GO:0005515(protein binding);GO:0070062(extracellular exosome);GO:0044267(cellular protein metabolic process);GO:0043687(post-translational protein modification);GO:0043312(neutrophil degranulation);GO:1904813(ficolin-1-rich granule lumen);GO:0005788(endoplasmic reticulum lumen);GO:1904724(tertiary granule lumen);GO:0097435(supramolecular fiber organization);GO:2000117(negative regulation of cysteine-type endopeptidase activity);GO:0001540(amyloid-beta binding);GO:0004866(endopeptidase inhibitor activity);GO:0006952(defense response);GO:0010711(negative regulation of collagen catabolic process);GO:0010716(negative regulation of extracellular matrix disassembly);GO:0034103(regulation of tissue remodeling);GO:0045861(negative regulation of proteolysis);GO:0060311(negative regulation of elastin catabolic process);GO:0060313(negative regulation of blood vessel remodeling);GO:0060313(negative regulation of blood vessel remodeling)","04970(Salivary secretion);04970(Salivary secretion)","K13899","NA","cystatin C [Source:HGNC Symbol;Acc:HGNC:2475]",{"v":21.3362771537212,"d":"21.34"},{"v":24.4697232127199,"d":"24.47"},{"v":0.871945994984943,"d":"0.87"},{"v":-0.197689312155994,"d":"-0.20"},{"v":0.793677948747078,"d":"0.79"},1,"down","no"]
["ENSG00000103222","ABCC1","ENST00000399410;ENST00000574761;ENST00000575422;ENST00000572053;ENST00000574224;ENST00000399408","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005215(transporter activity);GO:0055085(transmembrane transport);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0016787(hydrolase activity);GO:0005886(plasma membrane);GO:0042626(ATPase activity, coupled to transmembrane movement of substances);GO:0016887(ATPase activity);GO:0005887(integral component of plasma membrane);GO:0035461(vitamin transmembrane transport);GO:0070062(extracellular exosome);GO:0009235(cobalamin metabolic process);GO:0008559(xenobiotic-transporting ATPase activity);GO:0043225(ATPase-coupled anion transmembrane transporter activity);GO:0006855(drug transmembrane transport);GO:0042908(xenobiotic transport);GO:0099133(ATP hydrolysis coupled anion transmembrane transport);GO:0016323(basolateral plasma membrane);GO:0042493(response to drug);GO:0006691(leukotriene metabolic process);GO:0015420(cobalamin-transporting ATPase activity);GO:0015431(glutathione S-conjugate-exporting ATPase activity);GO:0034634(glutathione transmembrane transporter activity);GO:0015889(cobalamin transport);GO:0034775(glutathione transmembrane transport);GO:0034775(glutathione transmembrane transport)","02010(ABC transporters);04071(Sphingolipid signaling pathway);04977(Vitamin digestion and absorption);05206(MicroRNAs in cancer);01523(Antifolate resistance);01523(Antifolate resistance)","K05665","NA","ATP binding cassette subfamily C member 1 [Source:HGNC Symbol;Acc:HGNC:51]",{"v":4.57498984079208,"d":"4.57"},{"v":4.13543316541254,"d":"4.14"},{"v":1.10629035890505,"d":"1.11"},{"v":0.145730087539214,"d":"0.15"},{"v":0.794725413237226,"d":"0.79"},1,"up","no"]
["MSTRG.14744","STOML2","ENST00000356493;ENST00000487490;ENST00000619795;ENST00000452248;ENST00000488050","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005743(mitochondrial inner membrane);GO:0005739(mitochondrion);GO:0005886(plasma membrane);GO:0005856(cytoskeleton);GO:0045121(membrane raft);GO:0008289(lipid binding);GO:0005515(protein binding);GO:0005758(mitochondrial intermembrane space);GO:0008180(COP9 signalosome);GO:0005102(receptor binding);GO:0051259(protein oligomerization);GO:0050852(T cell receptor signaling pathway);GO:0015629(actin cytoskeleton);GO:0007005(mitochondrion organization);GO:0001772(immunological synapse);GO:1901612(cardiolipin binding);GO:0051020(GTPase binding);GO:0006851(mitochondrial calcium ion transmembrane transport);GO:0006874(cellular calcium ion homeostasis);GO:0042776(mitochondrial ATP synthesis coupled proton transport);GO:0042101(T cell receptor complex);GO:0019897(extrinsic component of plasma membrane);GO:0010918(positive regulation of mitochondrial membrane potential);GO:0035710(CD4-positive, alpha-beta T cell activation);GO:0034982(mitochondrial protein processing);GO:0010876(lipid localization);GO:0032623(interleukin-2 production);GO:0090297(positive regulation of mitochondrial DNA replication);GO:1900210(positive regulation of cardiolipin metabolic process);GO:1990046(stress-induced mitochondrial fusion);GO:1990046(stress-induced mitochondrial fusion)","NA","NA","NA","stomatin like 2 [Source:HGNC Symbol;Acc:HGNC:14559]",{"v":8.41637486600222,"d":"8.42"},{"v":9.6525407192691,"d":"9.65"},{"v":0.871933629785249,"d":"0.87"},{"v":-0.197709771380387,"d":"-0.20"},{"v":0.795408814560202,"d":"0.80"},1,"down","no"]
["MSTRG.6319","ZZEF1","MSTRG.6319.1;ENST00000573183;ENST00000570365;ENST00000572699;ENST00000572426;ENST00000571436;ENST00000573606;ENST00000574474;ENST00000575428;ENST00000573536","GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0005509(calcium ion binding);GO:0005509(calcium ion binding)","NA","NA","NA","zinc finger ZZ-type and EF-hand domain containing 1 [Source:HGNC Symbol;Acc:HGNC:29027]",{"v":4.37025158093334,"d":"4.37"},{"v":5.00420184550509,"d":"5.00"},{"v":0.873316408061921,"d":"0.87"},{"v":-0.195423648777225,"d":"-0.20"},{"v":0.796889649748843,"d":"0.80"},1,"down","no"]
["MSTRG.948","PSMD4","ENST00000368881;ENST00000368884;ENST00000437736;ENST00000461434;ENST00000470396;ENST00000469786;ENST00000427779;ENST00000453615;ENST00000445776;ENST00000491857;ENST00000476855;ENST00000462970","GO:0003723(RNA binding);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0005515(protein binding);GO:0000502(proteasome complex);GO:0006511(ubiquitin-dependent protein catabolic process);GO:0038095(Fc-epsilon receptor signaling pathway);GO:0005634(nucleus);GO:0042802(identical protein binding);GO:0043161(proteasome-mediated ubiquitin-dependent protein catabolic process);GO:0000165(MAPK cascade);GO:0000209(protein polyubiquitination);GO:0002223(stimulatory C-type lectin receptor signaling pathway);GO:0002479(antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent);GO:0006521(regulation of cellular amino acid metabolic process);GO:0010972(negative regulation of G2/M transition of mitotic cell cycle);GO:0016579(protein deubiquitination);GO:0031145(anaphase-promoting complex-dependent catabolic process);GO:0031146(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process);GO:0033209(tumor necrosis factor-mediated signaling pathway);GO:0038061(NIK/NF-kappaB signaling);GO:0043488(regulation of mRNA stability);GO:0043687(post-translational protein modification);GO:0050852(T cell receptor signaling pathway);GO:0051437(positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition);GO:0055085(transmembrane transport);GO:0060071(Wnt signaling pathway, planar cell polarity pathway);GO:0061418(regulation of transcription from RNA polymerase II promoter in response to hypoxia);GO:0090090(negative regulation of canonical Wnt signaling pathway);GO:0090263(positive regulation of canonical Wnt signaling pathway);GO:1902036(regulation of hematopoietic stem cell differentiation);GO:0008540(proteasome regulatory particle, base subcomplex);GO:0051436(negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle);GO:0022624(proteasome accessory complex);GO:0043248(proteasome assembly);GO:0031593(polyubiquitin binding);GO:0008134(transcription factor binding);GO:0005737(cytoplasm);GO:0005737(cytoplasm)","03050(Proteasome);05169(Epstein-Barr virus infection);05169(Epstein-Barr virus infection)","K03029","NA","proteasome 26S subunit, non-ATPase 4 [Source:HGNC Symbol;Acc:HGNC:9561]",{"v":14.0922109563925,"d":"14.09"},{"v":16.1398067707301,"d":"16.14"},{"v":0.873133808636981,"d":"0.87"},{"v":-0.195725329619051,"d":"-0.20"},{"v":0.797715210218692,"d":"0.80"},1,"down","no"]
["MSTRG.5407","ZNF710","ENST00000268154;ENST00000558883;MSTRG.5407.2;MSTRG.5407.3;ENST00000559419;ENST00000559360","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0003677(DNA binding)","NA","NA","NA","zinc finger protein 710 [Source:HGNC Symbol;Acc:HGNC:25352]",{"v":6.88474975977444,"d":"6.88"},{"v":7.87902779210526,"d":"7.88"},{"v":0.873807015463623,"d":"0.87"},{"v":-0.19461340620989,"d":"-0.19"},{"v":0.79838659394139,"d":"0.80"},1,"down","no"]
["ENSG00000009413","REV3L","ENST00000422377;ENST00000494858;ENST00000462119;ENST00000368802;ENST00000467500;ENST00000434009;ENST00000460981;ENST00000358835;ENST00000492520","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0016740(transferase activity);GO:0003677(DNA binding);GO:0090305(nucleic acid phosphodiester bond hydrolysis);GO:0005515(protein binding);GO:0006281(DNA repair);GO:0006974(cellular response to DNA damage stimulus);GO:0000166(nucleotide binding);GO:0008408(3'-5' exonuclease activity);GO:0016779(nucleotidyltransferase activity);GO:0003887(DNA-directed DNA polymerase activity);GO:0051536(iron-sulfur cluster binding);GO:0051539(4 iron, 4 sulfur cluster binding);GO:0006260(DNA replication);GO:0005654(nucleoplasm);GO:0006261(DNA-dependent DNA replication);GO:0042276(error-prone translesion synthesis);GO:0016035(zeta DNA polymerase complex);GO:0005730(nucleolus);GO:0005730(nucleolus)","03460(Fanconi anemia pathway);01524(Platinum drug resistance);01524(Platinum drug resistance)","K02350","EC:2.7.7.7","REV3 like, DNA directed polymerase zeta catalytic subunit [Source:HGNC Symbol;Acc:HGNC:9968]",{"v":1.65465745907445,"d":"1.65"},{"v":1.49901105303823,"d":"1.50"},{"v":1.10383272739767,"d":"1.10"},{"v":0.142521565560143,"d":"0.14"},{"v":0.798693236060829,"d":"0.80"},1,"up","no"]
["ENSG00000163138","PACRGL","ENST00000471979;ENST00000508952;ENST00000506745;ENST00000444671;ENST00000514485;ENST00000504630;ENST00000511160;ENST00000505160;ENST00000509625;ENST00000507634;ENST00000514292;ENST00000509469;ENST00000467997;ENST00000360916;ENST00000506648;ENST00000295290;ENST00000503585;ENST00000502938;ENST00000510051;ENST00000514663;ENST00000513459;ENST00000511089","GO:0005515(protein binding);GO:0005515(protein binding)","NA","NA","NA","parkin coregulated like [Source:HGNC Symbol;Acc:HGNC:28442]",{"v":0.332896638888889,"d":"0.33"},{"v":0.391551403521825,"d":"0.39"},{"v":0.850199069380512,"d":"0.85"},{"v":-0.234127415069125,"d":"-0.23"},{"v":0.8000786092956,"d":"0.80"},1,"down","no"]
["MSTRG.15199","RPS6KA3","MSTRG.15199.2;ENST00000379565;MSTRG.15199.3;ENST00000492128;ENST00000438357","GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0016740(transferase activity);GO:0000287(magnesium ion binding);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0035556(intracellular signal transduction);GO:0005515(protein binding);GO:0007049(cell cycle);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0032496(response to lipopolysaccharide);GO:0043066(negative regulation of apoptotic process);GO:0007165(signal transduction);GO:0007417(central nervous system development);GO:0045597(positive regulation of cell differentiation);GO:0001501(skeletal system development);GO:0030307(positive regulation of cell growth);GO:0043154(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process);GO:0043027(cysteine-type endopeptidase inhibitor activity involved in apoptotic process);GO:0043620(regulation of DNA-templated transcription in response to stress);GO:0002224(toll-like receptor signaling pathway);GO:0006915(apoptotic process);GO:0019901(protein kinase binding);GO:0018105(peptidyl-serine phosphorylation);GO:0043555(regulation of translation in response to stress);GO:0043555(regulation of translation in response to stress)","04010(MAPK signaling pathway);04150(mTOR signaling pathway);04114(Oocyte meiosis);04914(Progesterone-mediated oocyte maturation);04720(Long-term potentiation);04722(Neurotrophin signaling pathway);04931(Insulin resistance);04931(Insulin resistance)","K04373","EC:2.7.11.1","ribosomal protein S6 kinase A3 [Source:HGNC Symbol;Acc:HGNC:10432]",{"v":6.1771779380947,"d":"6.18"},{"v":7.0500852756073,"d":"7.05"},{"v":0.876184854028251,"d":"0.88"},{"v":-0.190692818833201,"d":"-0.19"},{"v":0.802034707838976,"d":"0.80"},1,"down","no"]
["MSTRG.5296","SNUPN;PTPN9;AC105036.3","ENST00000564675;ENST00000618819;ENST00000308588;ENST00000564644;ENST00000567437;ENST00000306726;ENST00000563835;ENST00000568078;ENST00000565138;ENST00000568707;ENST00000568162;ENST00000568108;ENST00000564086;ENST00000567875;ENST00000567134;ENST00000564970;ENST00000561731","GO:0005634(nucleus);GO:0003723(RNA binding);GO:0006810(transport);GO:0005737(cytoplasm);GO:0008565(protein transporter activity);GO:0006606(protein import into nucleus);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0005643(nuclear pore);GO:0000387(spliceosomal snRNP assembly);GO:0051170(nuclear import);GO:0000339(RNA cap binding);GO:0061015(snRNA import into nucleus);GO:0016787(hydrolase activity);GO:0004725(protein tyrosine phosphatase activity);GO:0016791(phosphatase activity);GO:0006470(protein dephosphorylation);GO:0016311(dephosphorylation);GO:0035335(peptidyl-tyrosine dephosphorylation);GO:0004721(phosphoprotein phosphatase activity);GO:0005515(protein binding);GO:0004726(non-membrane spanning protein tyrosine phosphatase activity);GO:0004726(non-membrane spanning protein tyrosine phosphatase activity)","03013(RNA transport);03013(RNA transport)","K13151","NA","snurportin 1 [Source:HGNC Symbol;Acc:HGNC:14245];protein tyrosine phosphatase, non-receptor type 9 [Source:HGNC Symbol;Acc:HGNC:9661]",{"v":2.25855790843949,"d":"2.26"},{"v":2.05542234036624,"d":"2.06"},{"v":1.09882911364924,"d":"1.10"},{"v":0.13596704046357,"d":"0.14"},{"v":0.802704134030892,"d":"0.80"},1,"up","no"]
["MSTRG.14455","UQCRB","ENST00000519322;ENST00000521948;ENST00000523920;ENST00000287022;ENST00000521036;ENST00000518876;ENST00000517523;MSTRG.14455.7;ENST00000518406;ENST00000517603","GO:0016020(membrane);GO:0055114(oxidation-reduction process);GO:0005743(mitochondrial inner membrane);GO:0005739(mitochondrion);GO:0005515(protein binding);GO:1902600(hydrogen ion transmembrane transport);GO:0070469(respiratory chain);GO:0008121(ubiquinol-cytochrome-c reductase activity);GO:0006122(mitochondrial electron transport, ubiquinol to cytochrome c);GO:0005750(mitochondrial respiratory chain complex III);GO:0009060(aerobic respiration);GO:0006119(oxidative phosphorylation);GO:0005746(mitochondrial respiratory chain);GO:0034551(mitochondrial respiratory chain complex III assembly);GO:0034551(mitochondrial respiratory chain complex III assembly)","00190(Oxidative phosphorylation);04260(Cardiac muscle contraction);05010(Alzheimer's disease);05012(Parkinson's disease);05016(Huntington's disease);04932(Non-alcoholic fatty liver disease (NAFLD));04932(Non-alcoholic fatty liver disease (NAFLD))","K00417","NA","ubiquinol-cytochrome c reductase binding protein [Source:HGNC Symbol;Acc:HGNC:12582]",{"v":9.83039709397838,"d":"9.83"},{"v":11.2032514548636,"d":"11.20"},{"v":0.877459292383442,"d":"0.88"},{"v":-0.188595898289311,"d":"-0.19"},{"v":0.804168798865354,"d":"0.80"},1,"down","no"]
["MSTRG.14646","ZNF7","ENST00000525266;ENST00000530776;ENST00000529819;ENST00000532382;ENST00000533314;ENST00000532777;ENST00000528130;ENST00000530682;ENST00000544249;ENST00000528017;ENST00000527218;ENST00000530082;ENST00000532393","GO:0003676(nucleic acid binding);GO:0006355(regulation of transcription, DNA-templated);GO:0005622(intracellular);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0007275(multicellular organism development);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016021(integral component of membrane)","NA","NA","NA","zinc finger protein 7 [Source:HGNC Symbol;Acc:HGNC:13139]",{"v":0.19063222027972,"d":"0.19"},{"v":0.170129362470862,"d":"0.17"},{"v":1.12051334061967,"d":"1.12"},{"v":0.164159825404545,"d":"0.16"},{"v":0.805347329387265,"d":"0.81"},1,"up","no"]
["ENSG00000166167","BTRC","ENST00000370187;ENST00000408038;ENST00000493877;ENST00000393441;ENST00000370183","GO:0043433(negative regulation of sequence-specific DNA binding transcription factor activity);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0046983(protein dimerization activity);GO:0016567(protein ubiquitination);GO:0016874(ligase activity);GO:0005515(protein binding);GO:0048511(rhythmic process);GO:0006511(ubiquitin-dependent protein catabolic process);GO:0016055(Wnt signaling pathway);GO:0045893(positive regulation of transcription, DNA-templated);GO:0038095(Fc-epsilon receptor signaling pathway);GO:0008013(beta-catenin binding);GO:0045309(protein phosphorylated amino acid binding);GO:0061630(ubiquitin protein ligase activity);GO:0000209(protein polyubiquitination);GO:0006470(protein dephosphorylation);GO:0030163(protein catabolic process);GO:0033598(mammary gland epithelial cell proliferation);GO:0042753(positive regulation of circadian rhythm);GO:0043122(regulation of I-kappaB kinase/NF-kappaB signaling);GO:0051726(regulation of cell cycle);GO:0060444(branching involved in mammary gland duct morphogenesis);GO:0060828(regulation of canonical Wnt signaling pathway);GO:0061136(regulation of proteasomal protein catabolic process);GO:0071407(cellular response to organic cyclic compound);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0031648(protein destabilization);GO:0002223(stimulatory C-type lectin receptor signaling pathway);GO:0038061(NIK/NF-kappaB signaling);GO:0043161(proteasome-mediated ubiquitin-dependent protein catabolic process);GO:0043687(post-translational protein modification);GO:0050852(T cell receptor signaling pathway);GO:0051437(positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition);GO:0016032(viral process);GO:0000086(G2/M transition of mitotic cell cycle);GO:0007165(signal transduction);GO:0004842(ubiquitin-protein transferase activity);GO:0045892(negative regulation of transcription, DNA-templated);GO:0051403(stress-activated MAPK cascade);GO:0042752(regulation of circadian rhythm);GO:0045862(positive regulation of proteolysis);GO:0045879(negative regulation of smoothened signaling pathway);GO:0019005(SCF ubiquitin ligase complex);GO:0031146(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process);GO:0031146(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)","04120(Ubiquitin mediated proteolysis);04310(Wnt signaling pathway);04340(Hedgehog signaling pathway);04390(Hippo signaling pathway);04114(Oocyte meiosis);04218(Cellular senescence);04710(Circadian rhythm);05131(Shigellosis);05131(Shigellosis)","K03362","NA","beta-transducin repeat containing E3 ubiquitin protein ligase [Source:HGNC Symbol;Acc:HGNC:1144]",{"v":0.868192081959776,"d":"0.87"},{"v":0.791237356721609,"d":"0.79"},{"v":1.09725871078309,"d":"1.10"},{"v":0.133903723333751,"d":"0.13"},{"v":0.80601399687802,"d":"0.81"},1,"up","no"]
["ENSG00000141698","NT5C3B","ENST00000523903;ENST00000470690;ENST00000460893;ENST00000495317;ENST00000435506;ENST00000415460;ENST00000521789;ENST00000469698;ENST00000476921;ENST00000481693;ENST00000520442;ENST00000517701;ENST00000445655;ENST00000475053;ENST00000486304;ENST00000393910","GO:0005737(cytoplasm);GO:0000287(magnesium ion binding);GO:0016311(dephosphorylation);GO:0008253(5'-nucleotidase activity);GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0016787(hydrolase activity);GO:0005515(protein binding);GO:0009117(nucleotide metabolic process);GO:0005829(cytosol);GO:0043928(exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay);GO:0043928(exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay)","00230(Purine metabolism);00240(Pyrimidine metabolism);00760(Nicotinate and nicotinamide metabolism);00760(Nicotinate and nicotinamide metabolism)","K01081","EC:3.1.3.5","5'-nucleotidase, cytosolic IIIB [Source:HGNC Symbol;Acc:HGNC:28300]",{"v":1.74951376483516,"d":"1.75"},{"v":1.59962515201465,"d":"1.60"},{"v":1.09370233559514,"d":"1.09"},{"v":0.129220144534533,"d":"0.13"},{"v":0.806500456329662,"d":"0.81"},1,"up","no"]
["ENSG00000170175","CHRNB1","ENST00000573209;ENST00000306071;ENST00000575379","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005216(ion channel activity);GO:0006811(ion transport);GO:0005886(plasma membrane);GO:0007165(signal transduction);GO:0030054(cell junction);GO:0045202(synapse);GO:0045211(postsynaptic membrane);GO:0005230(extracellular ligand-gated ion channel activity);GO:0060079(excitatory postsynaptic potential);GO:0005887(integral component of plasma membrane);GO:0060078(regulation of postsynaptic membrane potential);GO:0022848(acetylcholine-gated cation-selective channel activity);GO:0007274(neuromuscular synaptic transmission);GO:0042391(regulation of membrane potential);GO:0015464(acetylcholine receptor activity);GO:0007271(synaptic transmission, cholinergic);GO:0042166(acetylcholine binding);GO:0098655(cation transmembrane transport);GO:0015276(ligand-gated ion channel activity);GO:0015267(channel activity);GO:0001941(postsynaptic membrane organization);GO:0003009(skeletal muscle contraction);GO:0006812(cation transport);GO:0006936(muscle contraction);GO:0035095(behavioral response to nicotine);GO:0048747(muscle fiber development);GO:0050877(neurological system process);GO:0005892(acetylcholine-gated channel complex);GO:0034220(ion transmembrane transport);GO:0034220(ion transmembrane transport)","04080(Neuroactive ligand-receptor interaction);04080(Neuroactive ligand-receptor interaction)","K04812","NA","cholinergic receptor nicotinic beta 1 subunit [Source:HGNC Symbol;Acc:HGNC:1961]",{"v":0.411019412335412,"d":"0.41"},{"v":0.472146234234234,"d":"0.47"},{"v":0.870534132294918,"d":"0.87"},{"v":-0.200027230064129,"d":"-0.20"},{"v":0.807687164644059,"d":"0.81"},1,"down","no"]
["MSTRG.1826","RPS24","ENST00000440692;ENST00000478655;ENST00000372360;ENST00000482069;ENST00000480662;ENST00000360830;ENST00000435275;ENST00000476545;MSTRG.1826.13;ENST00000465692;ENST00000475468;ENST00000613865;ENST00000466129;ENST00000485708;ENST00000464716","GO:0003723(RNA binding);GO:0005634(nucleus);GO:0016020(membrane);GO:0006412(translation);GO:0030529(intracellular ribonucleoprotein complex);GO:0005622(intracellular);GO:0003735(structural constituent of ribosome);GO:0005840(ribosome);GO:0022627(cytosolic small ribosomal subunit);GO:0006364(rRNA processing);GO:0042274(ribosomal small subunit biogenesis);GO:0000462(maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA));GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0006413(translational initiation);GO:0031369(translation initiation factor binding);GO:0000184(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay);GO:0019083(viral transcription);GO:0006614(SRP-dependent cotranslational protein targeting to membrane);GO:0034101(erythrocyte homeostasis);GO:0015935(small ribosomal subunit);GO:0015935(small ribosomal subunit)","03010(Ribosome);03010(Ribosome)","K02974","NA","ribosomal protein S24 [Source:HGNC Symbol;Acc:HGNC:10411]",{"v":41.3099543963097,"d":"41.31"},{"v":37.7093592354593,"d":"37.71"},{"v":1.0954827988025,"d":"1.10"},{"v":0.131566831405118,"d":"0.13"},{"v":0.809054249205778,"d":"0.81"},1,"up","no"]
["ENSG00000052795","FNIP2","ENST00000264433;ENST00000504704;ENST00000512986","GO:0005737(cytoplasm);GO:0043086(negative regulation of catalytic activity);GO:0006974(cellular response to DNA damage stimulus);GO:0005515(protein binding);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0033138(positive regulation of peptidyl-serine phosphorylation);GO:0006468(protein phosphorylation);GO:0051087(chaperone binding);GO:0001932(regulation of protein phosphorylation);GO:0008630(intrinsic apoptotic signaling pathway in response to DNA damage);GO:0042030(ATPase inhibitor activity);GO:0031334(positive regulation of protein complex assembly);GO:0031334(positive regulation of protein complex assembly)","04150(mTOR signaling pathway);04150(mTOR signaling pathway)","K20401","NA","folliculin interacting protein 2 [Source:HGNC Symbol;Acc:HGNC:29280]",{"v":0.75379529812293,"d":"0.75"},{"v":0.68589741902834,"d":"0.69"},{"v":1.09899130279682,"d":"1.10"},{"v":0.136179969124678,"d":"0.14"},{"v":0.809818055675891,"d":"0.81"},1,"up","no"]
["MSTRG.8172","HNRNPUL1","MSTRG.8172.10;ENST00000599614;ENST00000595196;ENST00000392006;ENST00000602130;ENST00000263367;MSTRG.8172.8;ENST00000617774;ENST00000600332;ENST00000599521;ENST00000595018;ENST00000352456;ENST00000600493;ENST00000595806;ENST00000378215;ENST00000597725;ENST00000599719;ENST00000617305;ENST00000595336;ENST00000601336;ENST00000594207;ENST00000600596","GO:0006396(RNA processing);GO:0005654(nucleoplasm);GO:0009615(response to virus);GO:0003723(RNA binding);GO:0005634(nucleus);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0019013(viral nucleocapsid);GO:0030529(intracellular ribonucleoprotein complex);GO:0005515(protein binding);GO:0019899(enzyme binding);GO:0000398(mRNA splicing, via spliceosome);GO:0000398(mRNA splicing, via spliceosome)","05164(Influenza A);05164(Influenza A)","K15047","NA","heterogeneous nuclear ribonucleoprotein U like 1 [Source:HGNC Symbol;Acc:HGNC:17011]",{"v":31.4914703888125,"d":"31.49"},{"v":28.7870403125478,"d":"28.79"},{"v":1.09394609681656,"d":"1.09"},{"v":0.129541652416272,"d":"0.13"},{"v":0.811309264922439,"d":"0.81"},1,"up","no"]
["ENSG00000119661","DNAL1","ENST00000553645;ENST00000555631;ENST00000554113;ENST00000555919","GO:0043014(alpha-tubulin binding);GO:0036158(outer dynein arm assembly);GO:0045504(dynein heavy chain binding);GO:0036157(outer dynein arm);GO:0036157(outer dynein arm)","05016(Huntington's disease);05016(Huntington's disease)","K10411","NA","dynein axonemal light chain 1 [Source:HGNC Symbol;Acc:HGNC:23247]",{"v":0.217955337235479,"d":"0.22"},{"v":0.197511973435389,"d":"0.20"},{"v":1.10350442783043,"d":"1.10"},{"v":0.142092418467726,"d":"0.14"},{"v":0.811966513808867,"d":"0.81"},1,"up","no"]
["ENSG00000086475","SEPHS1","ENST00000327347;ENST00000545675;ENST00000413411;ENST00000494329;ENST00000378614;ENST00000425947","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0042802(identical protein binding);GO:0031965(nuclear membrane);GO:0005525(GTP binding);GO:0006464(cellular protein modification process);GO:0004756(selenide, water dikinase activity);GO:0016260(selenocysteine biosynthetic process);GO:0016260(selenocysteine biosynthetic process)","00450(Selenocompound metabolism);00450(Selenocompound metabolism)","K01008","EC:2.7.9.3","selenophosphate synthetase 1 [Source:HGNC Symbol;Acc:HGNC:19685]",{"v":3.138393875,"d":"3.14"},{"v":2.87037370936214,"d":"2.87"},{"v":1.09337465876435,"d":"1.09"},{"v":0.128787843574345,"d":"0.13"},{"v":0.813392375728695,"d":"0.81"},1,"up","no"]
["MSTRG.10731","RPL15","ENST00000465786;ENST00000412097;ENST00000422218;ENST00000354811;ENST00000611050;ENST00000490223;ENST00000307839;ENST00000413699;ENST00000434031;ENST00000456530;ENST00000435882;ENST00000415719","GO:0005634(nucleus);GO:0003723(RNA binding);GO:0016020(membrane);GO:0006412(translation);GO:0030529(intracellular ribonucleoprotein complex);GO:0005622(intracellular);GO:0003735(structural constituent of ribosome);GO:0005840(ribosome);GO:0005515(protein binding);GO:0045471(response to ethanol);GO:0022625(cytosolic large ribosomal subunit);GO:0031672(A band);GO:0005829(cytosol);GO:0045296(cadherin binding);GO:0070062(extracellular exosome);GO:0002181(cytoplasmic translation);GO:0006413(translational initiation);GO:0006364(rRNA processing);GO:0000184(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay);GO:0019083(viral transcription);GO:0006614(SRP-dependent cotranslational protein targeting to membrane);GO:0006614(SRP-dependent cotranslational protein targeting to membrane)","03010(Ribosome);03010(Ribosome)","K02877","NA","ribosomal protein L15 [Source:HGNC Symbol;Acc:HGNC:10306]",{"v":20.8668775303309,"d":"20.87"},{"v":23.6402443939951,"d":"23.64"},{"v":0.882684509625092,"d":"0.88"},{"v":-0.180030215032837,"d":"-0.18"},{"v":0.814527518933668,"d":"0.81"},1,"down","no"]
["ENSG00000149639","SOGA1","ENST00000237536;ENST00000279034;ENST00000463491","GO:0005615(extracellular space);GO:0010506(regulation of autophagy);GO:0005576(extracellular region);GO:0003674(molecular_function);GO:0070062(extracellular exosome);GO:0045721(negative regulation of gluconeogenesis);GO:0008286(insulin receptor signaling pathway);GO:0008286(insulin receptor signaling pathway)","NA","NA","NA","suppressor of glucose, autophagy associated 1 [Source:HGNC Symbol;Acc:HGNC:16111]",{"v":0.884679475475939,"d":"0.88"},{"v":1.0034033316367,"d":"1.00"},{"v":0.881678830020322,"d":"0.88"},{"v":-0.181674875294193,"d":"-0.18"},{"v":0.815068902104005,"d":"0.82"},1,"down","no"]
["ENSG00000012061","ERCC1","ENST00000300853;ENST00000589165;ENST00000592083;ENST00000588300;ENST00000592444;ENST00000592905;ENST00000591636;ENST00000587888;ENST00000588738;ENST00000013807;ENST00000340192;ENST00000589381","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0016787(hydrolase activity);GO:0003677(DNA binding);GO:0003684(damaged DNA binding);GO:0004519(endonuclease activity);GO:0006281(DNA repair);GO:0090305(nucleic acid phosphodiester bond hydrolysis);GO:0005515(protein binding);GO:0006974(cellular response to DNA damage stimulus);GO:0004518(nuclease activity);GO:0036297(interstrand cross-link repair);GO:0008022(protein C-terminus binding);GO:0019904(protein domain specific binding);GO:0006979(response to oxidative stress);GO:0003697(single-stranded DNA binding);GO:0006283(transcription-coupled nucleotide-excision repair);GO:0090656(t-circle formation);GO:0000014(single-stranded DNA endodeoxyribonuclease activity);GO:1990599(3' overhang single-stranded DNA endodeoxyribonuclease activity);GO:0000710(meiotic mismatch repair);GO:0006289(nucleotide-excision repair);GO:0006293(nucleotide-excision repair, preincision complex stabilization);GO:0006295(nucleotide-excision repair, DNA incision, 3'-to lesion);GO:0006296(nucleotide-excision repair, DNA incision, 5'-to lesion);GO:0006303(double-strand break repair via nonhomologous end joining);GO:0006310(DNA recombination);GO:0006312(mitotic recombination);GO:0032205(negative regulation of telomere maintenance);GO:0033683(nucleotide-excision repair, DNA incision);GO:0061819(telomeric DNA-containing double minutes formation);GO:0070911(global genome nucleotide-excision repair);GO:0070914(UV-damage excision repair);GO:1904431(positive regulation of t-circle formation);GO:1905765(negative regulation of protection from non-homologous end joining at telomere);GO:0000109(nucleotide-excision repair complex);GO:0000110(nucleotide-excision repair factor 1 complex);GO:0000784(nuclear chromosome, telomeric region);GO:0070522(ERCC4-ERCC1 complex);GO:0001094(TFIID-class transcription factor binding);GO:0000720(pyrimidine dimer repair by nucleotide-excision repair);GO:0001302(replicative cell aging);GO:0006302(double-strand break repair);GO:0006949(syncytium formation);GO:0007281(germ cell development);GO:0007283(spermatogenesis);GO:0007584(response to nutrient);GO:0008283(cell proliferation);GO:0008584(male gonad development);GO:0009650(UV protection);GO:0009744(response to sucrose);GO:0010165(response to X-ray);GO:0010259(multicellular organism aging);GO:0035166(post-embryonic hemopoiesis);GO:0035264(multicellular organism growth);GO:0045190(isotype switching);GO:0048468(cell development);GO:0048477(oogenesis);GO:0048568(embryonic organ development);GO:0051276(chromosome organization);GO:0005669(transcription factor TFIID complex);GO:0005669(transcription factor TFIID complex)","03420(Nucleotide excision repair);03460(Fanconi anemia pathway);01524(Platinum drug resistance);01524(Platinum drug resistance)","K10849","NA","ERCC excision repair 1, endonuclease non-catalytic subunit [Source:HGNC Symbol;Acc:HGNC:3433]",{"v":2.94152046251793,"d":"2.94"},{"v":2.69447068131277,"d":"2.69"},{"v":1.09168768579244,"d":"1.09"},{"v":0.126560183544132,"d":"0.13"},{"v":0.815644076369286,"d":"0.82"},1,"up","no"]
["ENSG00000094975","SUCO","ENST00000608151;ENST00000608566;ENST00000263688;ENST00000616058;ENST00000608804;ENST00000486569;ENST00000367723;ENST00000609685","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005783(endoplasmic reticulum);GO:0007275(multicellular organism development);GO:0032967(positive regulation of collagen biosynthetic process);GO:0045669(positive regulation of osteoblast differentiation);GO:0046850(regulation of bone remodeling);GO:0005791(rough endoplasmic reticulum);GO:0001503(ossification);GO:0030867(rough endoplasmic reticulum membrane);GO:0030867(rough endoplasmic reticulum membrane)","NA","NA","NA","SUN domain containing ossification factor [Source:HGNC Symbol;Acc:HGNC:1240]",{"v":1.24139501925513,"d":"1.24"},{"v":1.13214629452749,"d":"1.13"},{"v":1.09649700330754,"d":"1.10"},{"v":0.132901869175887,"d":"0.13"},{"v":0.816635708879588,"d":"0.82"},1,"up","no"]
["MSTRG.1340","RAB29","ENST00000414729;ENST00000367139;ENST00000468887;ENST00000528078;ENST00000533111;ENST00000492534;ENST00000446390;ENST00000437324;ENST00000235932","GO:0006810(transport);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0015031(protein transport);GO:0016192(vesicle-mediated transport);GO:0005829(cytosol);GO:0005525(GTP binding);GO:0000166(nucleotide binding);GO:0003924(GTPase activity);GO:0005794(Golgi apparatus);GO:0005886(plasma membrane);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0005802(trans-Golgi network);GO:0031982(vesicle);GO:0048471(perinuclear region of cytoplasm);GO:0030154(cell differentiation);GO:0070062(extracellular exosome);GO:0042147(retrograde transport, endosome to Golgi);GO:0005773(vacuole);GO:0017137(Rab GTPase binding);GO:0007005(mitochondrion organization);GO:0005739(mitochondrion);GO:0072657(protein localization to membrane);GO:0019003(GDP binding);GO:0019894(kinesin binding);GO:0070840(dynein complex binding);GO:0001921(positive regulation of receptor recycling);GO:0007030(Golgi organization);GO:0007416(synapse assembly);GO:0009617(response to bacterium);GO:0010977(negative regulation of neuron projection development);GO:0032438(melanosome organization);GO:0039694(viral RNA genome replication);GO:0042110(T cell activation);GO:0050862(positive regulation of T cell receptor signaling pathway);GO:0090316(positive regulation of intracellular protein transport);GO:1901214(regulation of neuron death);GO:1903441(protein localization to ciliary membrane);GO:1905279(regulation of retrograde transport, endosome to Golgi);GO:1990967(multi-organism toxin transport);GO:0005769(early endosome);GO:0005801(cis-Golgi network);GO:0020003(symbiont-containing vacuole);GO:0042470(melanosome);GO:0055037(recycling endosome);GO:0097708(intracellular vesicle);GO:0097708(intracellular vesicle)","NA","NA","NA","RAB29, member RAS oncogene family [Source:HGNC Symbol;Acc:HGNC:9789]",{"v":2.79156104894384,"d":"2.79"},{"v":2.55648298016486,"d":"2.56"},{"v":1.09195369990839,"d":"1.09"},{"v":0.126911685627111,"d":"0.13"},{"v":0.818252916983899,"d":"0.82"},1,"up","no"]
["ENSG00000169598","DFFB","ENST00000378209;ENST00000339350;ENST00000491998;ENST00000477548;ENST00000468793;ENST00000461150;ENST00000338895;ENST00000481945","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005730(nucleolus);GO:0016787(hydrolase activity);GO:0005622(intracellular);GO:0000790(nuclear chromatin);GO:0005829(cytosol);GO:0006915(apoptotic process);GO:0005515(protein binding);GO:0004518(nuclease activity);GO:0005654(nucleoplasm);GO:0006309(apoptotic DNA fragmentation);GO:0019899(enzyme binding);GO:0019904(protein domain specific binding);GO:0051260(protein homooligomerization);GO:0042802(identical protein binding);GO:0004536(deoxyribonuclease activity);GO:0097718(disordered domain specific binding);GO:0006308(DNA catabolic process);GO:0030263(apoptotic chromosome condensation);GO:0003677(DNA binding);GO:0003677(DNA binding)","04210(Apoptosis);04210(Apoptosis)","K02311","EC:3.-.-.-","DNA fragmentation factor subunit beta [Source:HGNC Symbol;Acc:HGNC:2773]",{"v":0.942433434108527,"d":"0.94"},{"v":1.0683687875969,"d":"1.07"},{"v":0.882123705830417,"d":"0.88"},{"v":-0.18094710659492,"d":"-0.18"},{"v":0.818526976446912,"d":"0.82"},1,"down","no"]
["ENSG00000225484","NUTM2B-AS1","ENST00000601369;ENST00000619625;ENST00000483080;ENST00000610681;ENST00000430963;ENST00000477192;ENST00000495430;ENST00000484794;ENST00000496359","NA","NA","NA","NA","NUTM2B antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:51204]",{"v":0.638385494476449,"d":"0.64"},{"v":0.7215036149102,"d":"0.72"},{"v":0.884798747066436,"d":"0.88"},{"v":-0.176578752264923,"d":"-0.18"},{"v":0.820488126506958,"d":"0.82"},1,"down","no"]
["ENSG00000161813","LARP4","ENST00000429001;ENST00000522085;ENST00000518561;ENST00000614335;ENST00000548697;ENST00000347328;ENST00000521120;ENST00000548174;ENST00000548993;ENST00000293618;ENST00000550260;ENST00000398473;ENST00000517559;ENST00000551886;ENST00000552445;ENST00000518444","GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0006412(translation);GO:0005829(cytosol);GO:0022627(cytosolic small ribosomal subunit);GO:0045727(positive regulation of translation);GO:0005515(protein binding);GO:0007010(cytoskeleton organization);GO:0022604(regulation of cell morphogenesis);GO:0010494(cytoplasmic stress granule);GO:0008143(poly(A) binding);GO:0005844(polysome);GO:0005844(polysome)","NA","NA","NA","La ribonucleoprotein domain family member 4 [Source:HGNC Symbol;Acc:HGNC:24320]",{"v":1.02931471166174,"d":"1.03"},{"v":1.16655269773176,"d":"1.17"},{"v":0.88235594813945,"d":"0.88"},{"v":-0.18056732910221,"d":"-0.18"},{"v":0.821763516793842,"d":"0.82"},1,"down","no"]
["MSTRG.9097","UGGT1","ENST00000376723;ENST00000259253;ENST00000465836;MSTRG.9097.5;ENST00000438277;ENST00000430075;ENST00000488439","GO:0006486(protein glycosylation);GO:0003980(UDP-glucose:glycoprotein glucosyltransferase activity);GO:0097359(UDP-glucosylation);GO:0016740(transferase activity);GO:0016757(transferase activity, transferring glycosyl groups);GO:0005783(endoplasmic reticulum);GO:0044322(endoplasmic reticulum quality control compartment);GO:0005788(endoplasmic reticulum lumen);GO:0005515(protein binding);GO:0070062(extracellular exosome);GO:0043234(protein complex);GO:1904380(endoplasmic reticulum mannose trimming);GO:0051082(unfolded protein binding);GO:0005793(endoplasmic reticulum-Golgi intermediate compartment);GO:0051084('de novo' posttranslational protein folding);GO:0018279(protein N-linked glycosylation via asparagine);GO:0030968(endoplasmic reticulum unfolded protein response);GO:0071712(ER-associated misfolded protein catabolic process);GO:0071712(ER-associated misfolded protein catabolic process)","04141(Protein processing in endoplasmic reticulum);04141(Protein processing in endoplasmic reticulum)","K11718","EC:2.4.1.-","UDP-glucose glycoprotein glucosyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:15663]",{"v":5.00546862172879,"d":"5.01"},{"v":4.59958213551855,"d":"4.60"},{"v":1.08824420876756,"d":"1.09"},{"v":0.122002342657812,"d":"0.12"},{"v":0.822054425760853,"d":"0.82"},1,"up","no"]
["ENSG00000025156","HSF2","ENST00000452194;ENST00000368455;ENST00000465214","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005654(nucleoplasm);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0043565(sequence-specific DNA binding);GO:0005515(protein binding);GO:0001228(transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding);GO:0003713(transcription coactivator activity);GO:0006366(transcription from RNA polymerase II promoter);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0000977(RNA polymerase II regulatory region sequence-specific DNA binding);GO:0001162(RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding);GO:0000979(RNA polymerase II core promoter sequence-specific DNA binding);GO:0042803(protein homodimerization activity);GO:0007283(spermatogenesis);GO:0007283(spermatogenesis)","NA","NA","NA","heat shock transcription factor 2 [Source:HGNC Symbol;Acc:HGNC:5225]",{"v":2.18982754219097,"d":"2.19"},{"v":2.00287746743153,"d":"2.00"},{"v":1.09334074490297,"d":"1.09"},{"v":0.128743093937925,"d":"0.13"},{"v":0.823110922908449,"d":"0.82"},1,"up","no"]
["MSTRG.14385","SNHG6","ENST00000521127;ENST00000520348;ENST00000520944;ENST00000521399;ENST00000520619","NA","NA","NA","NA","small nucleolar RNA host gene 6 [Source:HGNC Symbol;Acc:HGNC:32965]",{"v":10.0013030705694,"d":"10.00"},{"v":9.19737709703288,"d":"9.20"},{"v":1.08740817790279,"d":"1.09"},{"v":0.120893583143299,"d":"0.12"},{"v":0.824046334616453,"d":"0.82"},1,"up","no"]
["MSTRG.10895","DHX30","ENST00000457607;ENST00000445061;ENST00000474183;ENST00000472718;ENST00000492893;ENST00000619982;ENST00000461905;ENST00000415400;ENST00000446256;ENST00000471082;ENST00000395745;ENST00000476446;ENST00000441384","GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0005737(cytoplasm);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0005829(cytosol);GO:0016787(hydrolase activity);GO:0005739(mitochondrion);GO:0004386(helicase activity);GO:0005515(protein binding);GO:0042254(ribosome biogenesis);GO:0004004(ATP-dependent RNA helicase activity);GO:0003682(chromatin binding);GO:0042645(mitochondrial nucleoid);GO:0003725(double-stranded RNA binding);GO:0035770(ribonucleoprotein granule);GO:0006396(RNA processing);GO:1902775(mitochondrial large ribosomal subunit assembly);GO:1902775(mitochondrial large ribosomal subunit assembly)","NA","NA","NA","DExH-box helicase 30 [Source:HGNC Symbol;Acc:HGNC:16716]",{"v":4.17712995187854,"d":"4.18"},{"v":3.84978644595986,"d":"3.85"},{"v":1.08502900368986,"d":"1.09"},{"v":0.117733607573223,"d":"0.12"},{"v":0.825067724634866,"d":"0.83"},1,"up","no"]
["ENSG00000131845","ZNF304","ENST00000391705;ENST00000443917;ENST00000598744;ENST00000282286","GO:0003676(nucleic acid binding);GO:0046872(metal ion binding);GO:0006355(regulation of transcription, DNA-templated);GO:0005622(intracellular);GO:0005634(nucleus);GO:0006351(transcription, DNA-templated);GO:0016569(covalent chromatin modification);GO:0003677(DNA binding);GO:0007229(integrin-mediated signaling pathway);GO:0005515(protein binding);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0007265(Ras protein signal transduction);GO:0030335(positive regulation of cell migration);GO:0001525(angiogenesis);GO:0045766(positive regulation of angiogenesis);GO:0050679(positive regulation of epithelial cell proliferation);GO:1990841(promoter-specific chromatin binding);GO:2000811(negative regulation of anoikis);GO:0090309(positive regulation of methylation-dependent chromatin silencing);GO:0035562(negative regulation of chromatin binding);GO:1900114(positive regulation of histone H3-K9 trimethylation);GO:1902466(positive regulation of histone H3-K27 trimethylation);GO:1902466(positive regulation of histone H3-K27 trimethylation)","NA","NA","NA","zinc finger protein 304 [Source:HGNC Symbol;Acc:HGNC:13505]",{"v":1.10012324734216,"d":"1.10"},{"v":1.23850201692341,"d":"1.24"},{"v":0.888269241639994,"d":"0.89"},{"v":-0.170931059410877,"d":"-0.17"},{"v":0.825488366707221,"d":"0.83"},1,"down","no"]
["MSTRG.10079","SUMO3","ENST00000332859;ENST00000466861;ENST00000397898;ENST00000411651;ENST00000479153;ENST00000397893","GO:0016925(protein sumoylation);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005515(protein binding);GO:0005654(nucleoplasm);GO:0070062(extracellular exosome);GO:0016605(PML body);GO:0019899(enzyme binding);GO:0070911(global genome nucleotide-excision repair);GO:0031386(protein tag);GO:0043392(negative regulation of DNA binding);GO:0000776(kinetochore);GO:0000776(kinetochore)","03013(RNA transport);05418(Fluid shear stress and atherosclerosis);05418(Fluid shear stress and atherosclerosis)","K12160","NA","small ubiquitin-like modifier 3 [Source:HGNC Symbol;Acc:HGNC:11124]",{"v":17.2346091760615,"d":"17.23"},{"v":19.3919513704246,"d":"19.39"},{"v":0.888750639213476,"d":"0.89"},{"v":-0.170149402529678,"d":"-0.17"},{"v":0.826691477559867,"d":"0.83"},1,"down","no"]
["MSTRG.10063","MX2","ENST00000474368;ENST00000495892;ENST00000416447;MSTRG.10063.2;ENST00000330714;ENST00000494252;ENST00000496774;ENST00000493753;ENST00000481838;ENST00000418103;ENST00000436410;ENST00000482953;ENST00000435611;ENST00000398632","GO:0006810(transport);GO:0051028(mRNA transport);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0015031(protein transport);GO:0005525(GTP binding);GO:0000166(nucleotide binding);GO:0003924(GTPase activity);GO:0005515(protein binding);GO:0005643(nuclear pore);GO:0002376(immune system process);GO:0045087(innate immune response);GO:0051607(defense response to virus);GO:0005829(cytosol);GO:0008017(microtubule binding);GO:0009615(response to virus);GO:0051726(regulation of cell cycle);GO:0006952(defense response);GO:0060337(type I interferon signaling pathway);GO:0003374(dynamin family protein polymerization involved in mitochondrial fission);GO:0061025(membrane fusion);GO:0031966(mitochondrial membrane);GO:0035455(response to interferon-alpha);GO:0000266(mitochondrial fission);GO:0046822(regulation of nucleocytoplasmic transport);GO:0046822(regulation of nucleocytoplasmic transport)","NA","NA","NA","MX dynamin like GTPase 2 [Source:HGNC Symbol;Acc:HGNC:7533]",{"v":6.64469859063386,"d":"6.64"},{"v":7.47375988717713,"d":"7.47"},{"v":0.889070386384006,"d":"0.89"},{"v":-0.169630455284039,"d":"-0.17"},{"v":0.827373144093789,"d":"0.83"},1,"down","no"]
["MSTRG.8762","SERTAD2","ENST00000313349;ENST00000476805","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0030308(negative regulation of cell growth);GO:0003713(transcription coactivator activity);GO:0045893(positive regulation of transcription, DNA-templated);GO:0045893(positive regulation of transcription, DNA-templated)","NA","NA","NA","SERTA domain containing 2 [Source:HGNC Symbol;Acc:HGNC:30784]",{"v":6.3840222421103,"d":"6.38"},{"v":7.17507672649028,"d":"7.18"},{"v":0.889749682890579,"d":"0.89"},{"v":-0.168528581332994,"d":"-0.17"},{"v":0.828483488409262,"d":"0.83"},1,"down","no"]
["MSTRG.1853","IFIT1B","ENST00000371809","GO:0005515(protein binding);GO:0051607(defense response to virus)","05160(Hepatitis C);05168(Herpes simplex infection)","K14217","NA","interferon induced protein with tetratricopeptide repeats 1B [Source:HGNC Symbol;Acc:HGNC:23442]",{"v":8.007546,"d":"8.01"},{"v":7.388042,"d":"7.39"},{"v":1.08385225747228,"d":"1.08"},{"v":0.116168112836864,"d":"0.12"},{"v":0.82999676926696,"d":"0.83"},1,"up","no"]
["ENSG00000151233","GXYLT1","ENST00000398675;ENST00000280876","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016740(transferase activity);GO:0016757(transferase activity, transferring glycosyl groups);GO:0035252(UDP-xylosyltransferase activity);GO:0016266(O-glycan processing);GO:0016266(O-glycan processing)","00514(Other types of O-glycan biosynthesis);00514(Other types of O-glycan biosynthesis)","K13676","EC:2.4.2.-","glucoside xylosyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:27482]",{"v":1.117838,"d":"1.12"},{"v":1.030416,"d":"1.03"},{"v":1.0848414620891,"d":"1.08"},{"v":0.117484223711545,"d":"0.12"},{"v":0.830507360676909,"d":"0.83"},1,"up","no"]
["MSTRG.8506","ITGB1BP1","ENST00000456913;ENST00000355346;ENST00000359712;ENST00000483795;ENST00000360635;ENST00000494563;ENST00000490426;ENST00000465527;ENST00000497105;ENST00000488451;ENST00000460720;ENST00000464228;ENST00000467606;ENST00000460001;ENST00000463190;ENST00000470507;ENST00000238091;ENST00000492079;ENST00000497031","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0015031(protein transport);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0007155(cell adhesion);GO:0005886(plasma membrane);GO:0005856(cytoskeleton);GO:0042995(cell projection);GO:0005515(protein binding);GO:0048471(perinuclear region of cytoplasm);GO:0030154(cell differentiation);GO:0007219(Notch signaling pathway);GO:0007229(integrin-mediated signaling pathway);GO:0050880(regulation of blood vessel size);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0030027(lamellipodium);GO:0070062(extracellular exosome);GO:0031214(biomineral tissue development);GO:0071944(cell periphery);GO:0008285(negative regulation of cell proliferation);GO:0090314(positive regulation of protein targeting to membrane);GO:0008284(positive regulation of cell proliferation);GO:0001726(ruffle);GO:0005178(integrin binding);GO:0008565(protein transporter activity);GO:0043113(receptor clustering);GO:0032403(protein complex binding);GO:0001525(angiogenesis);GO:0045747(positive regulation of Notch signaling pathway);GO:0005092(GDP-dissociation inhibitor activity);GO:0019900(kinase binding);GO:0019901(protein kinase binding);GO:0002043(blood vessel endothelial cell proliferation involved in sprouting angiogenesis);GO:0006469(negative regulation of protein kinase activity);GO:0006933(negative regulation of cell adhesion involved in substrate-bound cell migration);GO:0007160(cell-matrix adhesion);GO:0010595(positive regulation of endothelial cell migration);GO:0010764(negative regulation of fibroblast migration);GO:0016477(cell migration);GO:0032091(negative regulation of protein binding);GO:0032148(activation of protein kinase B activity);GO:0033622(integrin activation);GO:0033628(regulation of cell adhesion mediated by integrin);GO:0035148(tube formation);GO:0035556(intracellular signal transduction);GO:0035924(cellular response to vascular endothelial growth factor stimulus);GO:0043087(regulation of GTPase activity);GO:0044344(cellular response to fibroblast growth factor stimulus);GO:0051451(myoblast migration);GO:0051496(positive regulation of stress fiber assembly);GO:0051781(positive regulation of cell division);GO:0051894(positive regulation of focal adhesion assembly);GO:0051895(negative regulation of focal adhesion assembly);GO:0051897(positive regulation of protein kinase B signaling);GO:0070373(negative regulation of ERK1 and ERK2 cascade);GO:0090051(negative regulation of cell migration involved in sprouting angiogenesis);GO:0090315(negative regulation of protein targeting to membrane);GO:1900025(negative regulation of substrate adhesion-dependent cell spreading);GO:2001044(regulation of integrin-mediated signaling pathway);GO:2001044(regulation of integrin-mediated signaling pathway)","NA","NA","NA","integrin subunit beta 1 binding protein 1 [Source:HGNC Symbol;Acc:HGNC:23927]",{"v":1.63789531117101,"d":"1.64"},{"v":1.51560611365678,"d":"1.52"},{"v":1.08068666153581,"d":"1.08"},{"v":0.111948283130933,"d":"0.11"},{"v":0.831369248719294,"d":"0.83"},1,"up","no"]
["MSTRG.6076","SNTB2;VPS4A;AC026464.4","ENST00000336278;ENST00000254950;ENST00000566354;ENST00000524887;ENST00000562754;ENST00000528525;ENST00000570054;ENST00000564399;ENST00000360496;ENST00000467311","GO:0003723(RNA binding);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0003779(actin binding);GO:0005198(structural molecule activity);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0030054(cell junction);GO:0005874(microtubule);GO:0031410(cytoplasmic vesicle);GO:0045202(synapse);GO:0005925(focal adhesion);GO:0005516(calmodulin binding);GO:0070062(extracellular exosome);GO:0043234(protein complex);GO:0030658(transport vesicle membrane);GO:0016010(dystrophin-associated glycoprotein complex);GO:0006810(transport);GO:0005634(nucleus);GO:0015031(protein transport);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0016787(hydrolase activity);GO:0051301(cell division);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0007049(cell cycle);GO:0048471(perinuclear region of cytoplasm);GO:0005764(lysosome);GO:0000922(spindle pole);GO:0005813(centrosome);GO:0030496(midbody);GO:0016192(vesicle-mediated transport);GO:0005768(endosome);GO:0031902(late endosome membrane);GO:0032466(negative regulation of cytokinesis);GO:0016197(endosomal transport);GO:0016236(macroautophagy);GO:0019058(viral life cycle);GO:0036258(multivesicular body assembly);GO:0016887(ATPase activity);GO:0005769(early endosome);GO:0005770(late endosome);GO:0008022(protein C-terminus binding);GO:0005774(vacuolar membrane);GO:0019904(protein domain specific binding);GO:1903543(positive regulation of exosomal secretion);GO:0006622(protein targeting to lysosome);GO:1903076(regulation of protein localization to plasma membrane);GO:0007080(mitotic metaphase plate congression);GO:0032880(regulation of protein localization);GO:0000920(cell separation after cytokinesis);GO:0006997(nucleus organization);GO:0039702(viral budding via host ESCRT complex);GO:1902188(positive regulation of viral release from host cell);GO:1904903(ESCRT III complex disassembly);GO:0000815(ESCRT III complex);GO:0042623(ATPase activity, coupled);GO:0019076(viral release from host cell);GO:0043162(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway);GO:0090611(ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway);GO:1903902(positive regulation of viral life cycle);GO:0090543(Flemming body);GO:0006900(membrane budding);GO:0034058(endosomal vesicle fusion);GO:0009838(abscission);GO:0032367(intracellular cholesterol transport);GO:0044878(mitotic cytokinesis checkpoint);GO:1903774(positive regulation of viral budding via host ESCRT complex);GO:0006998(nuclear envelope organization);GO:0061640(cytoskeleton-dependent cytokinesis);GO:0000916(actomyosin contractile ring contraction);GO:0061738(late endosomal microautophagy);GO:0072319(vesicle uncoating);GO:1904896(ESCRT complex disassembly);GO:0016010(dystrophin-associated glycoprotein complex)","04144(Endocytosis);04217(Necroptosis);04217(Necroptosis)","K12196","NA","syntrophin beta 2 [Source:HGNC Symbol;Acc:HGNC:11169];vacuolar protein sorting 4 homolog A [Source:HGNC Symbol;Acc:HGNC:13488]",{"v":3.34693453264715,"d":"3.35"},{"v":3.75618390350595,"d":"3.76"},{"v":0.891046503213856,"d":"0.89"},{"v":-0.166427367735797,"d":"-0.17"},{"v":0.831745304696723,"d":"0.83"},1,"down","no"]
["MSTRG.678","HS2ST1;AC093155.3;LINC01140","ENST00000370551;ENST00000370550;ENST00000370548;ENST00000484933;ENST00000476432;ENST00000619924;ENST00000591456","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016740(transferase activity);GO:0005794(Golgi apparatus);GO:0000139(Golgi membrane);GO:0008146(sulfotransferase activity);GO:0006024(glycosaminoglycan biosynthetic process);GO:0004394(heparan sulfate 2-O-sulfotransferase activity);GO:0004394(heparan sulfate 2-O-sulfotransferase activity)","00534(Glycosaminoglycan biosynthesis - heparan sulfate / heparin);00534(Glycosaminoglycan biosynthesis - heparan sulfate / heparin)","K02513","EC:2.8.2.-","heparan sulfate 2-O-sulfotransferase 1 [Source:HGNC Symbol;Acc:HGNC:5193];long intergenic non-protein coding RNA 1140 [Source:HGNC Symbol;Acc:HGNC:27922]",{"v":0.589394923551258,"d":"0.59"},{"v":0.661100126480275,"d":"0.66"},{"v":0.891536546346196,"d":"0.89"},{"v":-0.165634156092914,"d":"-0.17"},{"v":0.832771877434107,"d":"0.83"},1,"down","no"]
["ENSG00000186364","NUDT17","ENST00000334513;ENST00000498192;ENST00000444015;ENST00000460879;ENST00000477878","GO:0046872(metal ion binding);GO:0016787(hydrolase activity);GO:0016787(hydrolase activity)","NA","NA","NA","nudix hydrolase 17 [Source:HGNC Symbol;Acc:HGNC:26618]",{"v":0.84092109957755,"d":"0.84"},{"v":0.772333611345806,"d":"0.77"},{"v":1.08880552034014,"d":"1.09"},{"v":0.12274628656435,"d":"0.12"},{"v":0.833890942290169,"d":"0.83"},1,"up","no"]
["MSTRG.10595","TRABD","ENST00000395829;ENST00000463233;ENST00000395827;ENST00000380909;ENST00000472677;ENST00000303434","NA","NA","NA","NA","TraB domain containing [Source:HGNC Symbol;Acc:HGNC:28805]",{"v":9.10886263463368,"d":"9.11"},{"v":10.2082233111323,"d":"10.21"},{"v":0.892306364879406,"d":"0.89"},{"v":-0.16438896410633,"d":"-0.16"},{"v":0.834203969871944,"d":"0.83"},1,"down","no"]
["MSTRG.133","LZIC","ENST00000377223;ENST00000377213;ENST00000471853;ENST00000400903;ENST00000488540","GO:0008013(beta-catenin binding);GO:0010212(response to ionizing radiation);GO:0010212(response to ionizing radiation)","NA","NA","NA","leucine zipper and CTNNBIP1 domain containing [Source:HGNC Symbol;Acc:HGNC:17497]",{"v":3.40952081424481,"d":"3.41"},{"v":3.16287308876163,"d":"3.16"},{"v":1.0779821758766,"d":"1.08"},{"v":0.108333323742527,"d":"0.11"},{"v":0.835578178969412,"d":"0.84"},1,"up","no"]
["MSTRG.3491","MARS","ENST00000548202;ENST00000545888;ENST00000262027;ENST00000537638;ENST00000552914;ENST00000553162;ENST00000550449;ENST00000551805;ENST00000547665;ENST00000549074;ENST00000553123;ENST00000628866;ENST00000447721;ENST00000549133;ENST00000548146;ENST00000548944;ENST00000549827;ENST00000549603;ENST00000549048;MSTRG.3491.2;ENST00000548674;ENST00000547062;ENST00000546481;ENST00000546971;ENST00000547501;ENST00000548714;ENST00000548630;ENST00000551842;ENST00000551172","GO:0003723(RNA binding);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0006412(translation);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0005829(cytosol);GO:0016874(ligase activity);GO:0004812(aminoacyl-tRNA ligase activity);GO:0006418(tRNA aminoacylation for protein translation);GO:0000049(tRNA binding);GO:0070062(extracellular exosome);GO:0004825(methionine-tRNA ligase activity);GO:0006431(methionyl-tRNA aminoacylation);GO:0017101(aminoacyl-tRNA synthetase multienzyme complex);GO:0005730(nucleolus);GO:0009267(cellular response to starvation);GO:0009303(rRNA transcription);GO:0032869(cellular response to insulin stimulus);GO:0036120(cellular response to platelet-derived growth factor stimulus);GO:0071364(cellular response to epidermal growth factor stimulus);GO:1901838(positive regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter);GO:1901838(positive regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter)","00450(Selenocompound metabolism);00970(Aminoacyl-tRNA biosynthesis);00970(Aminoacyl-tRNA biosynthesis)","K01874","EC:6.1.1.10","methionyl-tRNA synthetase [Source:HGNC Symbol;Acc:HGNC:6898]",{"v":5.76331431791989,"d":"5.76"},{"v":6.45579965790583,"d":"6.46"},{"v":0.892734382000545,"d":"0.89"},{"v":-0.163697105177064,"d":"-0.16"},{"v":0.836386018166184,"d":"0.84"},1,"down","no"]
["ENSG00000232859","LYRM9","ENST00000460380;ENST00000508816;ENST00000582343;ENST00000503642;ENST00000379102;ENST00000508862;ENST00000379103","NA","NA","NA","NA","LYR motif containing 9 [Source:HGNC Symbol;Acc:HGNC:27314]",{"v":0.395919717100372,"d":"0.40"},{"v":0.446960459479554,"d":"0.45"},{"v":0.885804792579159,"d":"0.89"},{"v":-0.174939292051713,"d":"-0.17"},{"v":0.837929677788515,"d":"0.84"},1,"down","no"]
["MSTRG.12822","ZNRD1","ENST00000359374;ENST00000332435;ENST00000376785;ENST00000471008;ENST00000376782","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0006351(transcription, DNA-templated);GO:0006379(mRNA cleavage);GO:0005730(nucleolus);GO:0003899(DNA-directed 5'-3' RNA polymerase activity);GO:0005654(nucleoplasm);GO:0006139(nucleobase-containing compound metabolic process);GO:0045815(positive regulation of gene expression, epigenetic);GO:0001054(RNA polymerase I activity);GO:0006361(transcription initiation from RNA polymerase I promoter);GO:0006362(transcription elongation from RNA polymerase I promoter);GO:0006363(termination of RNA polymerase I transcription);GO:0005736(DNA-directed RNA polymerase I complex);GO:0005736(DNA-directed RNA polymerase I complex)","00230(Purine metabolism);00240(Pyrimidine metabolism);03020(RNA polymerase);03020(RNA polymerase)","K03000","NA","zinc ribbon domain containing 1 [Source:HGNC Symbol;Acc:HGNC:13182]",{"v":0.911694851579521,"d":"0.91"},{"v":0.846360121459695,"d":"0.85"},{"v":1.07719495338125,"d":"1.08"},{"v":0.107279375994827,"d":"0.11"},{"v":0.840209765360281,"d":"0.84"},1,"up","no"]
["ENSG00000078589","P2RY10","ENST00000171757;ENST00000475374;ENST00000544091","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0004930(G-protein coupled receptor activity);GO:0007186(G-protein coupled receptor signaling pathway);GO:0005886(plasma membrane);GO:0004871(signal transducer activity);GO:0007165(signal transduction);GO:0045028(G-protein coupled purinergic nucleotide receptor activity);GO:0035589(G-protein coupled purinergic nucleotide receptor signaling pathway);GO:0005887(integral component of plasma membrane);GO:0035025(positive regulation of Rho protein signal transduction);GO:0051482(positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway);GO:0051482(positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway)","04080(Neuroactive ligand-receptor interaction);04080(Neuroactive ligand-receptor interaction)","K04274","NA","purinergic receptor P2Y10 [Source:HGNC Symbol;Acc:HGNC:19906]",{"v":1.49056432334997,"d":"1.49"},{"v":1.68133989018303,"d":"1.68"},{"v":0.886533610516853,"d":"0.89"},{"v":-0.17375276685782,"d":"-0.17"},{"v":0.841100914701892,"d":"0.84"},1,"down","no"]
["MSTRG.6828","STAT5A","ENST00000546010;ENST00000590949;ENST00000444283;MSTRG.6828.2;ENST00000591556;ENST00000468096;ENST00000345506;ENST00000587646;ENST00000479417;ENST00000478897;ENST00000469124","GO:0043536(positive regulation of blood vessel endothelial cell migration);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0007165(signal transduction);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0004871(signal transducer activity);GO:0018108(peptidyl-tyrosine phosphorylation);GO:0005515(protein binding);GO:0001938(positive regulation of endothelial cell proliferation);GO:0038111(interleukin-7-mediated signaling pathway);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0007259(JAK-STAT cascade);GO:0004713(protein tyrosine kinase activity);GO:0060397(JAK-STAT cascade involved in growth hormone signaling pathway);GO:0007595(lactation);GO:0040014(regulation of multicellular organism growth);GO:0000255(allantoin metabolic process);GO:0006101(citrate metabolic process);GO:0006103(2-oxoglutarate metabolic process);GO:0006105(succinate metabolic process);GO:0006107(oxaloacetate metabolic process);GO:0006549(isoleucine metabolic process);GO:0006573(valine metabolic process);GO:0006600(creatine metabolic process);GO:0006631(fatty acid metabolic process);GO:0019530(taurine metabolic process);GO:0046449(creatinine metabolic process);GO:0046449(creatinine metabolic process)","04012(ErbB signaling pathway);04630(Jak-STAT signaling pathway);04217(Necroptosis);04658(Th1 and Th2 cell differentiation);04659(Th17 cell differentiation);04917(Prolactin signaling pathway);05200(Pathways in cancer);05203(Viral carcinogenesis);05221(Acute myeloid leukemia);05220(Chronic myeloid leukemia);05223(Non-small cell lung cancer);04933(AGE-RAGE signaling pathway in diabetic complications);05166(HTLV-I infection);05162(Measles);05161(Hepatitis B);05161(Hepatitis B)","K11223","NA","signal transducer and activator of transcription 5A [Source:HGNC Symbol;Acc:HGNC:11366]",{"v":9.82894878727842,"d":"9.83"},{"v":10.9599499217935,"d":"10.96"},{"v":0.896805994316988,"d":"0.90"},{"v":-0.157132173632414,"d":"-0.16"},{"v":0.842203618804722,"d":"0.84"},1,"down","no"]
["MSTRG.73","SLC35E2B","ENST00000480991;ENST00000614300;ENST00000481276;ENST00000611123;ENST00000617444","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016021(integral component of membrane)","NA","NA","NA","solute carrier family 35 member E2B [Source:HGNC Symbol;Acc:HGNC:33941]",{"v":5.45027402370459,"d":"5.45"},{"v":6.07115302608696,"d":"6.07"},{"v":0.897732934795988,"d":"0.90"},{"v":-0.155641771246051,"d":"-0.16"},{"v":0.843533082556211,"d":"0.84"},1,"down","no"]
["ENSG00000228409","CCT6P1","ENST00000434500;ENST00000442266","NA","NA","NA","NA","chaperonin containing TCP1 subunit 6 pseudogene 1 [Source:HGNC Symbol;Acc:HGNC:33094]",{"v":0.727703758682635,"d":"0.73"},{"v":0.820125853892216,"d":"0.82"},{"v":0.887307423889935,"d":"0.89"},{"v":-0.172494055659826,"d":"-0.17"},{"v":0.844157847703242,"d":"0.84"},1,"down","no"]
["ENSG00000164930","FZD6","ENST00000358755;ENST00000522484","GO:0043433(negative regulation of sequence-specific DNA binding transcription factor activity);GO:0090090(negative regulation of canonical Wnt signaling pathway);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0004871(signal transducer activity);GO:0007165(signal transduction);GO:0004888(transmembrane signaling receptor activity);GO:0004930(G-protein coupled receptor activity);GO:0007166(cell surface receptor signaling pathway);GO:0007186(G-protein coupled receptor signaling pathway);GO:0007275(multicellular organism development);GO:0016055(Wnt signaling pathway);GO:0030659(cytoplasmic vesicle membrane);GO:0031410(cytoplasmic vesicle);GO:0042813(Wnt-activated receptor activity);GO:0017147(Wnt-protein binding);GO:0031625(ubiquitin protein ligase binding);GO:0016324(apical plasma membrane);GO:0009986(cell surface);GO:0060071(Wnt signaling pathway, planar cell polarity pathway);GO:0035567(non-canonical Wnt signaling pathway);GO:0007223(Wnt signaling pathway, calcium modulating pathway);GO:1904693(midbrain morphogenesis);GO:0005887(integral component of plasma membrane);GO:0001736(establishment of planar polarity);GO:0001843(neural tube closure);GO:0001942(hair follicle development);GO:0030168(platelet activation);GO:0030901(midbrain development);GO:0033278(cell proliferation in midbrain);GO:0035880(embryonic nail plate morphogenesis);GO:0042472(inner ear morphogenesis);GO:0048105(establishment of body hair planar orientation);GO:0016327(apicolateral plasma membrane);GO:0045177(apical part of cell);GO:0045177(apical part of cell)","04310(Wnt signaling pathway);04390(Hippo signaling pathway);04150(mTOR signaling pathway);04550(Signaling pathways regulating pluripotency of stem cells);04916(Melanogenesis);05200(Pathways in cancer);05205(Proteoglycans in cancer);05225(Hepatocellular carcinoma);05226(Gastric cancer);05217(Basal cell carcinoma);05224(Breast cancer);05166(HTLV-I infection);05165(Human papillomavirus infection);05165(Human papillomavirus infection)","K02376","NA","frizzled class receptor 6 [Source:HGNC Symbol;Acc:HGNC:4044]",{"v":0.299682518081181,"d":"0.30"},{"v":0.273704335547356,"d":"0.27"},{"v":1.09491330300586,"d":"1.09"},{"v":0.130816639438065,"d":"0.13"},{"v":0.845258843843975,"d":"0.85"},1,"up","no"]
["MSTRG.7331","AC139530.1","ENST00000575312","NA","NA","NA","NA",null,{"v":1.337424,"d":"1.34"},{"v":1.235875,"d":"1.24"},{"v":1.08216769495297,"d":"1.08"},{"v":0.113924079507488,"d":"0.11"},{"v":0.845867862365494,"d":"0.85"},1,"up","no"]
["ENSG00000151062","CACNA2D4","ENST00000280663;ENST00000444595;ENST00000589502;ENST00000382722;ENST00000588896;ENST00000540728;ENST00000541444;ENST00000541331;ENST00000543405;ENST00000585385;ENST00000536818;ENST00000538450;ENST00000538027;ENST00000545595","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0046872(metal ion binding);GO:0005244(voltage-gated ion channel activity);GO:0006811(ion transport);GO:0034765(regulation of ion transmembrane transport);GO:0006816(calcium ion transport);GO:0005262(calcium channel activity);GO:0070588(calcium ion transmembrane transport);GO:0005886(plasma membrane);GO:0061337(cardiac conduction);GO:0050908(detection of light stimulus involved in visual perception);GO:0005245(voltage-gated calcium channel activity);GO:0005891(voltage-gated calcium channel complex);GO:0005891(voltage-gated calcium channel complex)","04010(MAPK signaling pathway);04921(Oxytocin signaling pathway);04260(Cardiac muscle contraction);04261(Adrenergic signaling in cardiomyocytes);05410(Hypertrophic cardiomyopathy (HCM));05412(Arrhythmogenic right ventricular cardiomyopathy (ARVC));05414(Dilated cardiomyopathy (DCM));05414(Dilated cardiomyopathy (DCM))","K04861","NA","calcium voltage-gated channel auxiliary subunit alpha2delta 4 [Source:HGNC Symbol;Acc:HGNC:20202]",{"v":0.325452119518262,"d":"0.33"},{"v":0.366356035083126,"d":"0.37"},{"v":0.888349278713034,"d":"0.89"},{"v":-0.170801071923841,"d":"-0.17"},{"v":0.84662654669979,"d":"0.85"},1,"down","no"]
["MSTRG.3368","CERS5","ENST00000422340;ENST00000317551;ENST00000438450;ENST00000550258;ENST00000550079;ENST00000551757;ENST00000546676;ENST00000549942;ENST00000547455;ENST00000549389;ENST00000550899;ENST00000380189;ENST00000547787;ENST00000548930;ENST00000551384;ENST00000551005;ENST00000547800;ENST00000547852;ENST00000542320;ENST00000546514","GO:0005634(nucleus);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0003677(DNA binding);GO:0005783(endoplasmic reticulum);GO:0016740(transferase activity);GO:0006629(lipid metabolic process);GO:0005789(endoplasmic reticulum membrane);GO:0006665(sphingolipid metabolic process);GO:0031965(nuclear membrane);GO:0030148(sphingolipid biosynthetic process);GO:0050291(sphingosine N-acyltransferase activity);GO:0046513(ceramide biosynthetic process);GO:0046513(ceramide biosynthetic process)","00600(Sphingolipid metabolism);04071(Sphingolipid signaling pathway);04071(Sphingolipid signaling pathway)","K04710","EC:2.3.1.24","ceramide synthase 5 [Source:HGNC Symbol;Acc:HGNC:23749]",{"v":1.7122078171581,"d":"1.71"},{"v":1.90565616520966,"d":"1.91"},{"v":0.89848727615022,"d":"0.90"},{"v":-0.154430021608413,"d":"-0.15"},{"v":0.84796920892552,"d":"0.85"},1,"down","no"]
["ENSG00000172830","SSH3","ENST00000308127;ENST00000376757;ENST00000532181;ENST00000527821;ENST00000529224;ENST00000532881;ENST00000534112;ENST00000531495","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016787(hydrolase activity);GO:0004725(protein tyrosine phosphatase activity);GO:0008138(protein tyrosine/serine/threonine phosphatase activity);GO:0016791(phosphatase activity);GO:0006470(protein dephosphorylation);GO:0016311(dephosphorylation);GO:0035335(peptidyl-tyrosine dephosphorylation);GO:0004721(phosphoprotein phosphatase activity);GO:0005856(cytoskeleton);GO:0050770(regulation of axonogenesis);GO:0003779(actin binding);GO:0010591(regulation of lamellipodium assembly);GO:0008064(regulation of actin polymerization or depolymerization);GO:0008064(regulation of actin polymerization or depolymerization)","04810(Regulation of actin cytoskeleton);04360(Axon guidance);04360(Axon guidance)","K05766","EC:3.1.3.16;EC:3.1.3.48","slingshot protein phosphatase 3 [Source:HGNC Symbol;Acc:HGNC:30581]",{"v":1.5459073120022,"d":"1.55"},{"v":1.43834522246636,"d":"1.44"},{"v":1.07478183113189,"d":"1.07"},{"v":0.104043838338043,"d":"0.10"},{"v":0.850119690978243,"d":"0.85"},1,"up","no"]
["ENSG00000135093","USP30","ENST00000257548;ENST00000377883;ENST00000491362;ENST00000479219;ENST00000539121;ENST00000536393","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016579(protein deubiquitination);GO:0016787(hydrolase activity);GO:0006511(ubiquitin-dependent protein catabolic process);GO:0036459(thiol-dependent ubiquitinyl hydrolase activity);GO:0005739(mitochondrion);GO:0008233(peptidase activity);GO:0008234(cysteine-type peptidase activity);GO:0006508(proteolysis);GO:0005741(mitochondrial outer membrane);GO:0004843(thiol-dependent ubiquitin-specific protease activity);GO:0008053(mitochondrial fusion);GO:0000422(mitophagy);GO:0004197(cysteine-type endopeptidase activity);GO:0035871(protein K11-linked deubiquitination);GO:0044313(protein K6-linked deubiquitination);GO:0044313(protein K6-linked deubiquitination)","04137(Mitophagy - animal);04137(Mitophagy - animal)","K11851","EC:3.4.19.12","ubiquitin specific peptidase 30 [Source:HGNC Symbol;Acc:HGNC:20065]",{"v":0.718630377409932,"d":"0.72"},{"v":0.801814323076923,"d":"0.80"},{"v":0.896255350805188,"d":"0.90"},{"v":-0.158018267898967,"d":"-0.16"},{"v":0.850615139880455,"d":"0.85"},1,"down","no"]
["ENSG00000121406","ZNF549","ENST00000240719;ENST00000594943;ENST00000602149;ENST00000376233","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0005622(intracellular);GO:0005622(intracellular)","NA","NA","NA","zinc finger protein 549 [Source:HGNC Symbol;Acc:HGNC:26632]",{"v":0.455023927147322,"d":"0.46"},{"v":0.42273714290333,"d":"0.42"},{"v":1.07637555579396,"d":"1.08"},{"v":0.106181533237692,"d":"0.11"},{"v":0.851380278377761,"d":"0.85"},1,"up","no"]
["MSTRG.14609","TOP1MT","ENST00000523676;ENST00000329245;ENST00000522043;ENST00000519139;ENST00000522041;ENST00000524092;ENST00000517857;ENST00000523417;ENST00000521193;ENST00000518007;ENST00000519591;ENST00000518951;ENST00000519977","GO:0003677(DNA binding);GO:0005694(chromosome);GO:0003917(DNA topoisomerase type I activity);GO:0006265(DNA topological change);GO:0016853(isomerase activity);GO:0005634(nucleus);GO:0005739(mitochondrion);GO:0003916(DNA topoisomerase activity);GO:0042645(mitochondrial nucleoid);GO:0006260(DNA replication);GO:0006260(DNA replication)","NA","NA","NA","topoisomerase (DNA) I, mitochondrial [Source:HGNC Symbol;Acc:HGNC:29787]",{"v":1.92747900341562,"d":"1.93"},{"v":2.13683208135383,"d":"2.14"},{"v":0.902026425115459,"d":"0.90"},{"v":-0.148758396634418,"d":"-0.15"},{"v":0.852011351736475,"d":"0.85"},1,"down","no"]
["MSTRG.6253","VPS9D1","ENST00000389386;ENST00000561976;ENST00000565023;ENST00000563798;ENST00000567379","GO:0043547(positive regulation of GTPase activity);GO:0005096(GTPase activator activity);GO:0005215(transporter activity);GO:0015986(ATP synthesis coupled proton transport);GO:0015986(ATP synthesis coupled proton transport)","NA","NA","NA","VPS9 domain containing 1 [Source:HGNC Symbol;Acc:HGNC:13526]",{"v":2.38016257001167,"d":"2.38"},{"v":2.64003826925321,"d":"2.64"},{"v":0.90156366206197,"d":"0.90"},{"v":-0.149498726692529,"d":"-0.15"},{"v":0.853221226886776,"d":"0.85"},1,"down","no"]
["ENSG00000143315","PIGM","ENST00000368090","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016740(transferase activity);GO:0016757(transferase activity, transferring glycosyl groups);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0016758(transferase activity, transferring hexosyl groups);GO:0006506(GPI anchor biosynthetic process);GO:0016254(preassembly of GPI anchor in ER membrane)","00563(Glycosylphosphatidylinositol(GPI)-anchor biosynthesis)","K05284","EC:2.4.1.-","phosphatidylinositol glycan anchor biosynthesis class M [Source:HGNC Symbol;Acc:HGNC:18858]",{"v":1.069656,"d":"1.07"},{"v":1.000577,"d":"1.00"},{"v":1.06903916440214,"d":"1.07"},{"v":0.0963147073649976,"d":"0.10"},{"v":0.855074999318822,"d":"0.86"},1,"up","no"]
["ENSG00000282393","AC016588.2","ENST00000632484","NA","NA","NA","NA",null,{"v":0.299122,"d":"0.30"},{"v":0.33829,"d":"0.34"},{"v":0.884217683053002,"d":"0.88"},{"v":-0.177526508528229,"d":"-0.18"},{"v":0.855393412611487,"d":"0.86"},1,"down","no"]
["ENSG00000138050","THUMPD2","ENST00000460072;ENST00000505747;ENST00000510781;ENST00000403537;ENST00000530522;ENST00000378727;ENST00000530095","GO:0003723(RNA binding);GO:0008168(methyltransferase activity);GO:0016740(transferase activity);GO:0032259(methylation);GO:0030488(tRNA methylation);GO:0016423(tRNA (guanine) methyltransferase activity);GO:0016423(tRNA (guanine) methyltransferase activity)","NA","NA","NA","THUMP domain containing 2 [Source:HGNC Symbol;Acc:HGNC:14890]",{"v":0.305794743918389,"d":"0.31"},{"v":0.347818351556369,"d":"0.35"},{"v":0.879179441079119,"d":"0.88"},{"v":-0.185770444496475,"d":"-0.19"},{"v":0.856418462682867,"d":"0.86"},1,"down","no"]
["ENSG00000143643","TTC13","ENST00000366661;ENST00000481976;ENST00000486879;ENST00000471302;ENST00000519379;ENST00000466507;ENST00000522821;ENST00000366662","NA","NA","NA","NA","tetratricopeptide repeat domain 13 [Source:HGNC Symbol;Acc:HGNC:26204]",{"v":5.06164922245964,"d":"5.06"},{"v":4.74396361823362,"d":"4.74"},{"v":1.06696628174065,"d":"1.07"},{"v":0.0935145848463236,"d":"0.09"},{"v":0.85692328581001,"d":"0.86"},1,"up","no"]
["ENSG00000117983","MUC5B","ENST00000529681","GO:0043231(intracellular membrane-bounded organelle);GO:0005576(extracellular region);GO:0005615(extracellular space);GO:0005886(plasma membrane);GO:0070701(mucus layer);GO:0005515(protein binding);GO:0070062(extracellular exosome);GO:0002223(stimulatory C-type lectin receptor signaling pathway);GO:0005796(Golgi lumen);GO:0016266(O-glycan processing)","04657(IL-17 signaling pathway);04970(Salivary secretion)","K13908","NA","mucin 5B, oligomeric mucus/gel-forming [Source:HGNC Symbol;Acc:HGNC:7516]",{"v":0.0549897940101086,"d":"0.05"},{"v":0.0511568130444134,"d":"0.05"},{"v":1.07492610930176,"d":"1.07"},{"v":0.104237491993567,"d":"0.10"},{"v":0.858695647746206,"d":"0.86"},1,"up","no"]
["ENSG00000126970","ZC4H2","ENST00000374839;ENST00000476032;ENST00000488831;ENST00000488608;ENST00000337990;ENST00000447788","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0046872(metal ion binding);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0007275(multicellular organism development);GO:0030054(cell junction);GO:0045202(synapse);GO:0045211(postsynaptic membrane);GO:0007399(nervous system development);GO:0007528(neuromuscular junction development);GO:0021522(spinal cord motor neuron differentiation);GO:0021522(spinal cord motor neuron differentiation)","NA","NA","NA","zinc finger C4H2-type containing [Source:HGNC Symbol;Acc:HGNC:24931]",{"v":0.407503409046975,"d":"0.41"},{"v":0.379885369418133,"d":"0.38"},{"v":1.07270098259152,"d":"1.07"},{"v":0.101247978189236,"d":"0.10"},{"v":0.860058150218561,"d":"0.86"},1,"up","no"]
["MSTRG.11375","PARL;AC131160.1;MAP6D1","ENST00000311101;ENST00000317096;ENST00000417784;ENST00000418450;ENST00000639401;ENST00000449306;ENST00000488202;ENST00000638817;ENST00000639900;ENST00000318631;ENST00000463801;ENST00000421484;ENST00000435888","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0004252(serine-type endopeptidase activity);GO:0006508(proteolysis);GO:0005634(nucleus);GO:0016787(hydrolase activity);GO:0005739(mitochondrion);GO:0005743(mitochondrial inner membrane);GO:0008233(peptidase activity);GO:0008236(serine-type peptidase activity);GO:1903214(regulation of protein targeting to mitochondrion);GO:0005515(protein binding);GO:0010821(regulation of mitochondrion organization);GO:0006851(mitochondrial calcium ion transmembrane transport);GO:0004175(endopeptidase activity);GO:2000377(regulation of reactive oxygen species metabolic process);GO:0030162(regulation of proteolysis);GO:0033619(membrane protein proteolysis);GO:0005737(cytoplasm);GO:0005794(Golgi apparatus);GO:0005856(cytoskeleton);GO:0008017(microtubule binding);GO:0000226(microtubule cytoskeleton organization);GO:0005516(calmodulin binding);GO:0005874(microtubule);GO:0048813(dendrite morphogenesis);GO:0007026(negative regulation of microtubule depolymerization);GO:0018009(N-terminal peptidyl-L-cysteine N-palmitoylation);GO:0032418(lysosome localization);GO:0005798(Golgi-associated vesicle);GO:0005801(cis-Golgi network);GO:0033619(membrane protein proteolysis)","NA","NA","NA","presenilin associated rhomboid like [Source:HGNC Symbol;Acc:HGNC:18253];MAP6 domain containing 1 [Source:HGNC Symbol;Acc:HGNC:25753]",{"v":3.50325464245586,"d":"3.50"},{"v":3.87032101504815,"d":"3.87"},{"v":0.905158675168002,"d":"0.91"},{"v":-0.14375737472259,"d":"-0.14"},{"v":0.860600952425309,"d":"0.86"},1,"down","no"]
["MSTRG.6934","NSF","ENST00000398238;ENST00000575068;ENST00000571172;ENST00000576040;ENST00000576346;ENST00000571864","GO:0006810(transport);GO:0005737(cytoplasm);GO:0015031(protein transport);GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0005829(cytosol);GO:0016787(hydrolase activity);GO:0005765(lysosomal membrane);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0000139(Golgi membrane);GO:0006887(exocytosis);GO:0045026(plasma membrane fusion);GO:0070062(extracellular exosome);GO:0006890(retrograde vesicle-mediated transport, Golgi to ER);GO:0016887(ATPase activity);GO:0006888(ER to Golgi vesicle-mediated transport);GO:0017137(Rab GTPase binding);GO:0032403(protein complex binding);GO:0048208(COPII vesicle coating);GO:0030165(PDZ domain binding);GO:0017157(regulation of exocytosis);GO:0019901(protein kinase binding);GO:0001921(positive regulation of receptor recycling);GO:0014069(postsynaptic density);GO:0000149(SNARE binding);GO:0017075(syntaxin-1 binding);GO:0043198(dendritic shaft);GO:0019905(syntaxin binding);GO:0035255(ionotropic glutamate receptor binding);GO:0042623(ATPase activity, coupled);GO:0006813(potassium ion transport);GO:0006886(intracellular protein transport);GO:0016192(vesicle-mediated transport);GO:0035494(SNARE complex disassembly);GO:0045732(positive regulation of protein catabolic process);GO:0005795(Golgi stack);GO:0043209(myelin sheath);GO:0043209(myelin sheath)","04962(Vasopressin-regulated water reabsorption);04727(GABAergic synapse);04721(Synaptic vesicle cycle);04721(Synaptic vesicle cycle)","K06027","EC:3.6.4.6","N-ethylmaleimide sensitive factor, vesicle fusing ATPase [Source:HGNC Symbol;Acc:HGNC:8016]",{"v":6.40006438261738,"d":"6.40"},{"v":6.0180515978022,"d":"6.02"},{"v":1.06347781812883,"d":"1.06"},{"v":0.0887899420815839,"d":"0.09"},{"v":0.861598304151726,"d":"0.86"},1,"up","no"]
["MSTRG.13656","SUMF2","ENST00000434526;ENST00000483327;ENST00000413952;ENST00000413756;ENST00000447501;ENST00000423763;ENST00000395435;ENST00000395436;ENST00000275607;ENST00000342190;ENST00000531229;ENST00000498777;ENST00000451338;ENST00000461912;ENST00000452216;ENST00000529457;ENST00000437307;ENST00000438133","GO:0042803(protein homodimerization activity);GO:0005783(endoplasmic reticulum);GO:0046872(metal ion binding);GO:0005788(endoplasmic reticulum lumen);GO:0043687(post-translational protein modification);GO:0043687(post-translational protein modification)","NA","NA","NA","sulfatase modifying factor 2 [Source:HGNC Symbol;Acc:HGNC:20415]",{"v":6.42358218019995,"d":"6.42"},{"v":7.08709008022434,"d":"7.09"},{"v":0.906377950256929,"d":"0.91"},{"v":-0.141815330200599,"d":"-0.14"},{"v":0.862280595172266,"d":"0.86"},1,"down","no"]
["ENSG00000110172","CHORDC1","ENST00000320585;ENST00000529726;ENST00000529402;ENST00000533739;ENST00000533062;ENST00000457199;ENST00000533724;ENST00000525317;ENST00000529987","GO:0046872(metal ion binding);GO:0005515(protein binding);GO:0005575(cellular_component);GO:0061077(chaperone-mediated protein folding);GO:0051879(Hsp90 protein binding);GO:1900034(regulation of cellular response to heat);GO:0005524(ATP binding);GO:0008270(zinc ion binding);GO:0043531(ADP binding);GO:0010824(regulation of centrosome duplication);GO:2000299(negative regulation of Rho-dependent protein serine/threonine kinase activity);GO:2000299(negative regulation of Rho-dependent protein serine/threonine kinase activity)","NA","NA","NA","cysteine and histidine rich domain containing 1 [Source:HGNC Symbol;Acc:HGNC:14525]",{"v":1.37544096996715,"d":"1.38"},{"v":1.29788349450962,"d":"1.30"},{"v":1.05975688556455,"d":"1.06"},{"v":0.083733340054305,"d":"0.08"},{"v":0.863547057588926,"d":"0.86"},1,"up","no"]
["MSTRG.3408","HNRNPA1","ENST00000547276;ENST00000340913;MSTRG.3408.4;ENST00000546500;ENST00000547708;ENST00000547566;ENST00000547870;ENST00000550994;ENST00000548688;ENST00000550482;ENST00000551679;ENST00000551665;MSTRG.3408.8","GO:0005634(nucleus);GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0006397(mRNA processing);GO:0006810(transport);GO:0008380(RNA splicing);GO:0051028(mRNA transport);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005654(nucleoplasm);GO:0019013(viral nucleocapsid);GO:0030529(intracellular ribonucleoprotein complex);GO:0005515(protein binding);GO:0005681(spliceosomal complex);GO:0070062(extracellular exosome);GO:0016032(viral process);GO:0000398(mRNA splicing, via spliceosome);GO:0019904(protein domain specific binding);GO:0032212(positive regulation of telomere maintenance via telomerase);GO:0008543(fibroblast growth factor receptor signaling pathway);GO:0016070(RNA metabolic process);GO:0071013(catalytic step 2 spliceosome);GO:0061752(telomeric repeat-containing RNA binding);GO:0032211(negative regulation of telomere maintenance via telomerase);GO:0003697(single-stranded DNA binding);GO:0003727(single-stranded RNA binding);GO:0036002(pre-mRNA binding);GO:0098505(G-rich strand telomeric DNA binding);GO:0000381(regulation of alternative mRNA splicing, via spliceosome);GO:0006405(RNA export from nucleus);GO:0042149(cellular response to glucose starvation);GO:0051168(nuclear export);GO:0051170(nuclear import);GO:1903936(cellular response to sodium arsenite);GO:1903936(cellular response to sodium arsenite)","03040(Spliceosome);03040(Spliceosome)","K12741","NA","heterogeneous nuclear ribonucleoprotein A1 [Source:HGNC Symbol;Acc:HGNC:5031]",{"v":21.5748965108028,"d":"21.57"},{"v":20.3272428767096,"d":"20.33"},{"v":1.06137839950359,"d":"1.06"},{"v":0.0859390933513755,"d":"0.09"},{"v":0.863747488837091,"d":"0.86"},1,"up","no"]
["ENSG00000101665","SMAD7","ENST00000262158;ENST00000587336;ENST00000589634;ENST00000588190","GO:0005737(cytoplasm);GO:0043433(negative regulation of sequence-specific DNA binding transcription factor activity);GO:0060373(regulation of ventricular cardiac muscle cell membrane depolarization);GO:0060412(ventricular septum morphogenesis);GO:0030336(negative regulation of cell migration);GO:0010719(negative regulation of epithelial to mesenchymal transition);GO:0030512(negative regulation of transforming growth factor beta receptor signaling pathway);GO:0005634(nucleus);GO:0030514(negative regulation of BMP signaling pathway);GO:0046872(metal ion binding);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0005622(intracellular);GO:0001650(fibrillar center);GO:0005813(centrosome);GO:0005515(protein binding);GO:0007179(transforming growth factor beta receptor signaling pathway);GO:0005667(transcription factor complex);GO:0016579(protein deubiquitination);GO:0043234(protein complex);GO:0005913(cell-cell adherens junction);GO:0005886(plasma membrane);GO:0030509(BMP signaling pathway);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0044212(transcription regulatory region DNA binding);GO:0050821(protein stabilization);GO:0032436(positive regulation of proteasomal ubiquitin-dependent protein catabolic process);GO:0048844(artery morphogenesis);GO:0010801(negative regulation of peptidyl-threonine phosphorylation);GO:0008013(beta-catenin binding);GO:0016342(catenin complex);GO:0005518(collagen binding);GO:0030617(transforming growth factor beta receptor, inhibitory cytoplasmic mediator activity);GO:0031625(ubiquitin protein ligase binding);GO:0034713(type I transforming growth factor beta receptor binding);GO:0048185(activin binding);GO:0070411(I-SMAD binding);GO:0001657(ureteric bud development);GO:0002725(negative regulation of T cell cytokine production);GO:0010717(regulation of epithelial to mesenchymal transition);GO:0010944(negative regulation of transcription by competitive promoter binding);GO:0017015(regulation of transforming growth factor beta receptor signaling pathway);GO:0022409(positive regulation of cell-cell adhesion);GO:0031397(negative regulation of protein ubiquitination);GO:0031398(positive regulation of protein ubiquitination);GO:0032925(regulation of activin receptor signaling pathway);GO:0033137(negative regulation of peptidyl-serine phosphorylation);GO:0034333(adherens junction assembly);GO:0034616(response to laminar fluid shear stress);GO:0034629(cellular protein complex localization);GO:0051444(negative regulation of ubiquitin-protein transferase activity);GO:0055010(ventricular cardiac muscle tissue morphogenesis);GO:0055117(regulation of cardiac muscle contraction);GO:0060389(pathway-restricted SMAD protein phosphorylation);GO:0060394(negative regulation of pathway-restricted SMAD protein phosphorylation);GO:0071560(cellular response to transforming growth factor beta stimulus);GO:1990830(cellular response to leukemia inhibitory factor);GO:2000317(negative regulation of T-helper 17 type immune response);GO:2000320(negative regulation of T-helper 17 cell differentiation);GO:2000320(negative regulation of T-helper 17 cell differentiation)","04350(TGF-beta signaling pathway);04390(Hippo signaling pathway);04390(Hippo signaling pathway)","K19631","NA","SMAD family member 7 [Source:HGNC Symbol;Acc:HGNC:6773]",{"v":1.34403565222102,"d":"1.34"},{"v":1.26359987811484,"d":"1.26"},{"v":1.06365604769303,"d":"1.06"},{"v":0.0890317048715464,"d":"0.09"},{"v":0.865384403934384,"d":"0.87"},1,"up","no"]
["MSTRG.3121","AC010186.2;AC092821.3;AC092821.1;AC010186.4;GOT2P3","ENST00000575094;ENST00000633848;ENST00000641639;ENST00000611052;ENST00000545363;ENST00000641304;ENST00000641608;ENST00000573622;ENST00000520314;ENST00000574035;ENST00000576948;ENST00000537668;ENST00000426641;ENST00000518709;ENST00000642112","GO:0005615(extracellular space);GO:0005576(extracellular region);GO:0010951(negative regulation of endopeptidase activity);GO:0004866(endopeptidase inhibitor activity);GO:0004866(endopeptidase inhibitor activity)","NA","NA","NA","glutamic-oxaloacetic transaminase 2 pseudogene 3 [Source:HGNC Symbol;Acc:HGNC:4436]",{"v":0.3686489743603,"d":"0.37"},{"v":0.406896632980098,"d":"0.41"},{"v":0.906001535722541,"d":"0.91"},{"v":-0.142414599166165,"d":"-0.14"},{"v":0.86643814317256,"d":"0.87"},1,"down","no"]
["MSTRG.15200","SMS","ENST00000404933;ENST00000379404;ENST00000457085;ENST00000478094","GO:0016740(transferase activity);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0006597(spermine biosynthetic process);GO:0016768(spermine synthase activity);GO:0006596(polyamine biosynthetic process);GO:0006595(polyamine metabolic process);GO:0006555(methionine metabolic process);GO:0008215(spermine metabolic process);GO:0008215(spermine metabolic process)","00270(Cysteine and methionine metabolism);00330(Arginine and proline metabolism);00410(beta-Alanine metabolism);00480(Glutathione metabolism);00480(Glutathione metabolism)","K00802","EC:2.5.1.22","spermine synthase [Source:HGNC Symbol;Acc:HGNC:11123]",{"v":12.831367000463,"d":"12.83"},{"v":14.1112405564815,"d":"14.11"},{"v":0.909301131187177,"d":"0.91"},{"v":-0.137169947303927,"d":"-0.14"},{"v":0.866890783403783,"d":"0.87"},1,"down","no"]
["MSTRG.1905","COX15","ENST00000370483;ENST00000016171;ENST00000497381","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005634(nucleus);GO:0055114(oxidation-reduction process);GO:0016627(oxidoreductase activity, acting on the CH-CH group of donors);GO:0005739(mitochondrion);GO:0031966(mitochondrial membrane);GO:0004129(cytochrome-c oxidase activity);GO:0005743(mitochondrial inner membrane);GO:0006783(heme biosynthetic process);GO:0007585(respiratory gaseous exchange);GO:1902600(hydrogen ion transmembrane transport);GO:0006123(mitochondrial electron transport, cytochrome c to oxygen);GO:0006784(heme a biosynthetic process);GO:0008535(respiratory chain complex IV assembly);GO:0045333(cellular respiration);GO:0070069(cytochrome complex);GO:0005746(mitochondrial respiratory chain);GO:0005746(mitochondrial respiratory chain)","00190(Oxidative phosphorylation);00860(Porphyrin and chlorophyll metabolism);00860(Porphyrin and chlorophyll metabolism)","K02259","NA","COX15, cytochrome c oxidase assembly homolog [Source:HGNC Symbol;Acc:HGNC:2263]",{"v":2.84626415034714,"d":"2.85"},{"v":3.12630759588221,"d":"3.13"},{"v":0.910423578951755,"d":"0.91"},{"v":-0.135390172572109,"d":"-0.14"},{"v":0.8682132023326,"d":"0.87"},1,"down","no"]
["MSTRG.14899","KIAA0368","ENST00000259335;ENST00000602447;ENST00000338205;ENST00000602978;ENST00000465499","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005783(endoplasmic reticulum);GO:0032947(protein complex scaffold);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0000502(proteasome complex);GO:0031410(cytoplasmic vesicle);GO:0005813(centrosome);GO:0005815(microtubule organizing center);GO:0043248(proteasome assembly);GO:0005768(endosome);GO:0003674(molecular_function);GO:0005769(early endosome);GO:0005770(late endosome);GO:0030433(ubiquitin-dependent ERAD pathway);GO:0005793(endoplasmic reticulum-Golgi intermediate compartment);GO:0030139(endocytic vesicle);GO:0030134(ER to Golgi transport vesicle);GO:0005771(multivesicular body);GO:0005771(multivesicular body)","NA","NA","NA","KIAA0368 [Source:HGNC Symbol;Acc:HGNC:29020]",{"v":3.38138879595218,"d":"3.38"},{"v":3.71599346502545,"d":"3.72"},{"v":0.909955528118514,"d":"0.91"},{"v":-0.136132056093249,"d":"-0.14"},{"v":0.869040032119971,"d":"0.87"},1,"down","no"]
["MSTRG.2418","PATL1","ENST00000300146;ENST00000531919","GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016607(nuclear speck);GO:0005515(protein binding);GO:0000932(P-body);GO:0005829(cytosol);GO:0030014(CCR4-NOT complex);GO:0016605(PML body);GO:0043928(exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay);GO:0008266(poly(U) RNA binding);GO:0034046(poly(G) binding);GO:0000290(deadenylation-dependent decapping of nuclear-transcribed mRNA);GO:0033962(cytoplasmic mRNA processing body assembly);GO:0033962(cytoplasmic mRNA processing body assembly)","03018(RNA degradation);03018(RNA degradation)","K12617","NA","PAT1 homolog 1, processing body mRNA decay factor [Source:HGNC Symbol;Acc:HGNC:26721]",{"v":7.22114278447873,"d":"7.22"},{"v":7.92267566339411,"d":"7.92"},{"v":0.911452530846777,"d":"0.91"},{"v":-0.133760573340732,"d":"-0.13"},{"v":0.870114734958075,"d":"0.87"},1,"down","no"]
["MSTRG.14138","CDK5","ENST00000485972;ENST00000297518;ENST00000487703;ENST00000469108;ENST00000476691","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0005829(cytosol);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0051301(cell division);GO:0005886(plasma membrane);GO:0030054(cell junction);GO:0042995(cell projection);GO:0005515(protein binding);GO:0007049(cell cycle);GO:0048511(rhythmic process);GO:0006915(apoptotic process);GO:0045202(synapse);GO:0045211(postsynaptic membrane);GO:0007399(nervous system development);GO:0098793(presynapse);GO:0030425(dendrite);GO:0002039(p53 binding);GO:0004693(cyclin-dependent protein serine/threonine kinase activity);GO:0005176(ErbB-2 class receptor binding);GO:0008092(cytoskeletal protein binding);GO:0019901(protein kinase binding);GO:0030549(acetylcholine receptor activator activity);GO:0043125(ErbB-3 class receptor binding);GO:0046875(ephrin receptor binding);GO:0050321(tau-protein kinase activity);GO:0001764(neuron migration);GO:0001963(synaptic transmission, dopaminergic);GO:0006886(intracellular protein transport);GO:0006887(exocytosis);GO:0006913(nucleocytoplasmic transport);GO:0007160(cell-matrix adhesion);GO:0007409(axonogenesis);GO:0007416(synapse assembly);GO:0007519(skeletal muscle tissue development);GO:0008045(motor neuron axon guidance);GO:0008306(associative learning);GO:0008542(visual learning);GO:0009611(response to wounding);GO:0014044(Schwann cell development);GO:0016477(cell migration);GO:0018105(peptidyl-serine phosphorylation);GO:0018107(peptidyl-threonine phosphorylation);GO:0019233(sensory perception of pain);GO:0021537(telencephalon development);GO:0021549(cerebellum development);GO:0021695(cerebellar cortex development);GO:0021697(cerebellar cortex formation);GO:0021766(hippocampus development);GO:0021819(layer formation in cerebral cortex);GO:0021954(central nervous system neuron development);GO:0021987(cerebral cortex development);GO:0022038(corpus callosum development);GO:0030182(neuron differentiation);GO:0030334(regulation of cell migration);GO:0030517(negative regulation of axon extension);GO:0030866(cortical actin cytoskeleton organization);GO:0030900(forebrain development);GO:0031175(neuron projection development);GO:0031397(negative regulation of protein ubiquitination);GO:0031914(negative regulation of synaptic plasticity);GO:0032092(positive regulation of protein binding);GO:0032801(receptor catabolic process);GO:0035249(synaptic transmission, glutamatergic);GO:0035418(protein localization to synapse);GO:0042220(response to cocaine);GO:0042501(serine phosphorylation of STAT protein);GO:0043113(receptor clustering);GO:0043525(positive regulation of neuron apoptotic process);GO:0045055(regulated exocytosis);GO:0045786(negative regulation of cell cycle);GO:0045860(positive regulation of protein kinase activity);GO:0045956(positive regulation of calcium ion-dependent exocytosis);GO:0046777(protein autophosphorylation);GO:0046826(negative regulation of protein export from nucleus);GO:0048148(behavioral response to cocaine);GO:0048167(regulation of synaptic plasticity);GO:0048488(synaptic vesicle endocytosis);GO:0048812(neuron projection morphogenesis);GO:0048813(dendrite morphogenesis);GO:0051402(neuron apoptotic process);GO:0060078(regulation of postsynaptic membrane potential);GO:0060079(excitatory postsynaptic potential);GO:0061001(regulation of dendritic spine morphogenesis);GO:0070509(calcium ion import);GO:0090314(positive regulation of protein targeting to membrane);GO:1901216(positive regulation of neuron death);GO:2000273(positive regulation of receptor activity);GO:0005856(cytoskeleton);GO:0014069(postsynaptic density);GO:0016533(cyclin-dependent protein kinase 5 holoenzyme complex);GO:0030027(lamellipodium);GO:0030175(filopodium);GO:0030424(axon);GO:0030426(growth cone);GO:0031594(neuromuscular junction);GO:0043025(neuronal cell body);GO:0005654(nucleoplasm);GO:0043204(perikaryon);GO:0007268(chemical synaptic transmission);GO:0042981(regulation of apoptotic process);GO:1901796(regulation of signal transduction by p53 class mediator);GO:0008283(cell proliferation);GO:0016241(regulation of macroautophagy);GO:1901215(negative regulation of neuron death);GO:0016079(synaptic vesicle exocytosis);GO:2000251(positive regulation of actin cytoskeleton reorganization);GO:0048675(axon extension);GO:0048709(oligodendrocyte differentiation);GO:0071156(regulation of cell cycle arrest);GO:1903421(regulation of synaptic vesicle recycling);GO:0045861(negative regulation of proteolysis);GO:0045892(negative regulation of transcription, DNA-templated);GO:0045892(negative regulation of transcription, DNA-templated)","04360(Axon guidance);05010(Alzheimer's disease);05030(Cocaine addiction);05030(Cocaine addiction)","K02090","EC:2.7.11.22","cyclin dependent kinase 5 [Source:HGNC Symbol;Acc:HGNC:1774]",{"v":1.41574301293397,"d":"1.42"},{"v":1.33479857998639,"d":"1.33"},{"v":1.06064168344291,"d":"1.06"},{"v":0.0849373529262661,"d":"0.08"},{"v":0.871329150449853,"d":"0.87"},1,"up","no"]
["MSTRG.15505","CH17-340M24.3","ENST00000360656","NA","NA","NA","NA","uncharacterized protein BC009467 [Source:NCBI gene;Acc:158960]",{"v":1.335335,"d":"1.34"},{"v":1.227317,"d":"1.23"},{"v":1.08801149173359,"d":"1.09"},{"v":0.121693794620892,"d":"0.12"},{"v":0.872502726098306,"d":"0.87"},1,"up","no"]
["MSTRG.11973","EEF1A1P13","ENST00000503537","NA","NA","NA","NA","eukaryotic translation elongation factor 1 alpha 1 pseudogene 13 [Source:HGNC Symbol;Acc:HGNC:3196]",{"v":17.761808,"d":"17.76"},{"v":16.813457,"d":"16.81"},{"v":1.05640428378292,"d":"1.06"},{"v":0.0791620568446892,"d":"0.08"},{"v":0.87315670670509,"d":"0.87"},1,"up","no"]
["MSTRG.1149","SH2D1B","ENST00000367929;ENST00000493550","GO:0005515(protein binding);GO:0002376(immune system process);GO:0045087(innate immune response);GO:0002250(adaptive immune response);GO:0050776(regulation of immune response);GO:0005829(cytosol);GO:0005622(intracellular);GO:0030674(protein binding, bridging);GO:0045089(positive regulation of innate immune response);GO:0002366(leukocyte activation involved in immune response);GO:0002717(positive regulation of natural killer cell mediated immunity);GO:0002717(positive regulation of natural killer cell mediated immunity)","04650(Natural killer cell mediated cytotoxicity);04650(Natural killer cell mediated cytotoxicity)","K07989","NA","SH2 domain containing 1B [Source:HGNC Symbol;Acc:HGNC:30416]",{"v":11.777228448695,"d":"11.78"},{"v":11.1567923736146,"d":"11.16"},{"v":1.05561061408185,"d":"1.06"},{"v":0.0780777620351199,"d":"0.08"},{"v":0.874168858348438,"d":"0.87"},1,"up","no"]
["ENSG00000164818","DNAAF5","ENST00000297440;ENST00000403952;ENST00000491496;ENST00000461576;ENST00000486546","GO:0005737(cytoplasm);GO:0045505(dynein intermediate chain binding);GO:0030030(cell projection organization);GO:0003341(cilium movement);GO:0036159(inner dynein arm assembly);GO:0036158(outer dynein arm assembly);GO:0036158(outer dynein arm assembly)","NA","NA","NA","dynein axonemal assembly factor 5 [Source:HGNC Symbol;Acc:HGNC:26013]",{"v":0.72782770253608,"d":"0.73"},{"v":0.690061663303909,"d":"0.69"},{"v":1.0547284992639,"d":"1.05"},{"v":0.0768716783877805,"d":"0.08"},{"v":0.875935947459858,"d":"0.88"},1,"up","no"]
["ENSG00000087258","GNAO1","ENST00000564798;ENST00000640560;ENST00000638705;ENST00000262494;ENST00000639251;ENST00000563661;ENST00000640390;ENST00000262493;ENST00000568375;ENST00000638185","GO:0016020(membrane);GO:0005525(GTP binding);GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0007186(G-protein coupled receptor signaling pathway);GO:0007165(signal transduction);GO:0003924(GTPase activity);GO:0004871(signal transducer activity);GO:0005886(plasma membrane);GO:0019001(guanyl nucleotide binding);GO:0031683(G-protein beta/gamma-subunit complex binding);GO:0007188(adenylate cyclase-modulating G-protein coupled receptor signaling pathway);GO:0006457(protein folding);GO:0005834(heterotrimeric G-protein complex);GO:0006936(muscle contraction);GO:0007223(Wnt signaling pathway, calcium modulating pathway);GO:0031821(G-protein coupled serotonin receptor binding);GO:0031852(mu-type opioid receptor binding);GO:0051430(corticotropin-releasing hormone receptor 1 binding);GO:0007212(dopamine receptor signaling pathway);GO:0032403(protein complex binding);GO:0032794(GTPase activating protein binding);GO:0007568(aging);GO:0007626(locomotory behavior);GO:0008016(regulation of heart contraction);GO:0009987(cellular process);GO:0010243(response to organonitrogen compound);GO:0014070(response to organic cyclic compound);GO:0030900(forebrain development);GO:0031175(neuron projection development);GO:0034097(response to cytokine);GO:0042493(response to drug);GO:0042542(response to hydrogen peroxide);GO:0043278(response to morphine);GO:0043547(positive regulation of GTPase activity);GO:0051926(negative regulation of calcium ion transport);GO:0030425(dendrite);GO:0043005(neuron projection);GO:0043209(myelin sheath);GO:0043234(protein complex);GO:0044297(cell body);GO:0044297(cell body)","04015(Rap1 signaling pathway);04915(Estrogen signaling pathway);04921(Oxytocin signaling pathway);04926(Relaxin signaling pathway);04916(Melanogenesis);04724(Glutamatergic synapse);04727(GABAergic synapse);04725(Cholinergic synapse);04728(Dopaminergic synapse);04726(Serotonergic synapse);04730(Long-term depression);04723(Retrograde endocannabinoid signaling);04713(Circadian entrainment);05032(Morphine addiction);05034(Alcoholism);05145(Toxoplasmosis);05142(Chagas disease (American trypanosomiasis));05142(Chagas disease (American trypanosomiasis))","K04534","NA","G protein subunit alpha o1 [Source:HGNC Symbol;Acc:HGNC:4389]",{"v":0.14944215361028,"d":"0.15"},{"v":0.139056431335329,"d":"0.14"},{"v":1.07468710490568,"d":"1.07"},{"v":0.103916680364653,"d":"0.10"},{"v":0.876398994644219,"d":"0.88"},1,"up","no"]
["ENSG00000008256","CYTH3","ENST00000350796;ENST00000461891;ENST00000495176;ENST00000478541;ENST00000465320;ENST00000466543;ENST00000482460;ENST00000396741","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0005886(plasma membrane);GO:0043547(positive regulation of GTPase activity);GO:0005515(protein binding);GO:0005086(ARF guanyl-nucleotide exchange factor activity);GO:0032012(regulation of ARF protein signal transduction);GO:0005085(guanyl-nucleotide exchange factor activity);GO:0008289(lipid binding);GO:0031234(extrinsic component of cytoplasmic side of plasma membrane);GO:0005547(phosphatidylinositol-3,4,5-trisphosphate binding);GO:0000139(Golgi membrane);GO:0045785(positive regulation of cell adhesion);GO:0048193(Golgi vesicle transport);GO:0090162(establishment of epithelial cell polarity);GO:0001726(ruffle);GO:0001726(ruffle)","04072(Phospholipase D signaling pathway);04144(Endocytosis);04144(Endocytosis)","K18441","NA","cytohesin 3 [Source:HGNC Symbol;Acc:HGNC:9504]",{"v":1.39356961707989,"d":"1.39"},{"v":1.52281146539256,"d":"1.52"},{"v":0.915129448884631,"d":"0.92"},{"v":-0.127952261813495,"d":"-0.13"},{"v":0.878147880531847,"d":"0.88"},1,"down","no"]
["MSTRG.1807","SEC24C;FUT11","ENST00000465076;ENST00000465695;ENST00000489264;MSTRG.1807.1;ENST00000394790;ENST00000345254;ENST00000496827;ENST00000477008;ENST00000339365;ENST00000635550","GO:0006810(transport);GO:0006886(intracellular protein transport);GO:0015031(protein transport);GO:0008270(zinc ion binding);GO:0006888(ER to Golgi vesicle-mediated transport);GO:0030127(COPII vesicle coat);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005794(Golgi apparatus);GO:0005829(cytosol);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005515(protein binding);GO:0000139(Golgi membrane);GO:0048471(perinuclear region of cytoplasm);GO:0016192(vesicle-mediated transport);GO:0003674(molecular_function);GO:0000149(SNARE binding);GO:0019886(antigen processing and presentation of exogenous peptide antigen via MHC class II);GO:0048208(COPII vesicle coating);GO:0012507(ER to Golgi transport vesicle membrane);GO:0002474(antigen processing and presentation of peptide antigen via MHC class I);GO:0090110(cargo loading into COPII-coated vesicle);GO:0001701(in utero embryonic development);GO:0016021(integral component of membrane);GO:0016740(transferase activity);GO:0016757(transferase activity, transferring glycosyl groups);GO:0006486(protein glycosylation);GO:0032580(Golgi cisterna membrane);GO:0070062(extracellular exosome);GO:0036065(fucosylation);GO:0008417(fucosyltransferase activity);GO:0046920(alpha-(1->3)-fucosyltransferase activity);GO:0001701(in utero embryonic development)","04141(Protein processing in endoplasmic reticulum);04141(Protein processing in endoplasmic reticulum)","K14007","NA","SEC24 homolog C, COPII coat complex component [Source:HGNC Symbol;Acc:HGNC:10705];fucosyltransferase 11 [Source:HGNC Symbol;Acc:HGNC:19233]",{"v":9.77464458844391,"d":"9.77"},{"v":9.28819520967044,"d":"9.29"},{"v":1.05237286338114,"d":"1.05"},{"v":0.0736459525805158,"d":"0.07"},{"v":0.878428218899976,"d":"0.88"},1,"up","no"]
["ENSG00000224531","SMIM13","ENST00000416247","GO:0016020(membrane);GO:0016021(integral component of membrane)","NA","NA","NA","small integral membrane protein 13 [Source:HGNC Symbol;Acc:HGNC:27356]",{"v":0.604423,"d":"0.60"},{"v":0.573575,"d":"0.57"},{"v":1.05378198143225,"d":"1.05"},{"v":0.0755764164613516,"d":"0.08"},{"v":0.879663051286682,"d":"0.88"},1,"up","no"]
["ENSG00000158006","PAFAH2","ENST00000374282;ENST00000374284;ENST00000441420;ENST00000493892;ENST00000439092;ENST00000464540;ENST00000476611","GO:0005737(cytoplasm);GO:0016787(hydrolase activity);GO:0006629(lipid metabolic process);GO:0016042(lipid catabolic process);GO:0005789(endoplasmic reticulum membrane);GO:0007596(blood coagulation);GO:0005543(phospholipid binding);GO:0003847(1-alkyl-2-acetylglycerophosphocholine esterase activity);GO:0043066(negative regulation of apoptotic process);GO:0043066(negative regulation of apoptotic process)","00565(Ether lipid metabolism);00565(Ether lipid metabolism)","K01062","EC:3.1.1.47","platelet activating factor acetylhydrolase 2 [Source:HGNC Symbol;Acc:HGNC:8579]",{"v":4.08857045345502,"d":"4.09"},{"v":3.8864307053455,"d":"3.89"},{"v":1.05201166917282,"d":"1.05"},{"v":0.0731507074480757,"d":"0.07"},{"v":0.881174377690835,"d":"0.88"},1,"up","no"]
["MSTRG.12304","FSTL4","MSTRG.12304.1","NA","NA","NA","NA",null,{"v":3.701943,"d":"3.70"},{"v":4.039935,"d":"4.04"},{"v":0.916337267802576,"d":"0.92"},{"v":-0.126049399370022,"d":"-0.13"},{"v":0.881757097902223,"d":"0.88"},1,"down","no"]
["MSTRG.12709","ACOT13","ENST00000230048;ENST00000476436","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016787(hydrolase activity);GO:0005829(cytosol);GO:0005739(mitochondrion);GO:0005856(cytoskeleton);GO:0005819(spindle);GO:0070062(extracellular exosome);GO:0047617(acyl-CoA hydrolase activity);GO:0006637(acyl-CoA metabolic process);GO:0051289(protein homotetramerization);GO:0051289(protein homotetramerization)","NA","NA","NA","acyl-CoA thioesterase 13 [Source:HGNC Symbol;Acc:HGNC:20999]",{"v":1.17321277401001,"d":"1.17"},{"v":1.11796394788348,"d":"1.12"},{"v":1.04941914829286,"d":"1.05"},{"v":0.0695910195598389,"d":"0.07"},{"v":0.883331847978354,"d":"0.88"},1,"up","no"]
["ENSG00000107537","PHYH","ENST00000396913;ENST00000396920;ENST00000463730;ENST00000464049;ENST00000479604;ENST00000263038","GO:0046872(metal ion binding);GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0006631(fatty acid metabolic process);GO:0005515(protein binding);GO:0048037(cofactor binding);GO:0051213(dioxygenase activity);GO:0005777(peroxisome);GO:0005782(peroxisomal matrix);GO:0031418(L-ascorbic acid binding);GO:0008198(ferrous iron binding);GO:0031406(carboxylic acid binding);GO:0048244(phytanoyl-CoA dioxygenase activity);GO:0001561(fatty acid alpha-oxidation);GO:0006103(2-oxoglutarate metabolic process);GO:0006720(isoprenoid metabolic process);GO:0097089(methyl-branched fatty acid metabolic process);GO:0003824(catalytic activity);GO:0005739(mitochondrion);GO:0005739(mitochondrion)","04146(Peroxisome);04146(Peroxisome)","K00477","EC:1.14.11.18","phytanoyl-CoA 2-hydroxylase [Source:HGNC Symbol;Acc:HGNC:8940]",{"v":0.700160716651878,"d":"0.70"},{"v":0.765958591245194,"d":"0.77"},{"v":0.914097347630306,"d":"0.91"},{"v":-0.129580280298853,"d":"-0.13"},{"v":0.883719636563842,"d":"0.88"},1,"down","no"]
["MSTRG.7936","CHERP;SMIM7;SLC35E1;MED26;AC008764.1;AC008764.4;AC008764.7","ENST00000198939;ENST00000487416;ENST00000593409;ENST00000546361;ENST00000595753;ENST00000263390;ENST00000488894;ENST00000421082;ENST00000597711;ENST00000461488;ENST00000487803;ENST00000602194;ENST00000546538;ENST00000627144;ENST00000598608;ENST00000463051;ENST00000597261;ENST00000594662;ENST00000600432;ENST00000598492;ENST00000599310;ENST00000465250;ENST00000470077;ENST00000436553;ENST00000481671;ENST00000469055;ENST00000599872;ENST00000600060;ENST00000461364;ENST00000409035;ENST00000594507;ENST00000409648;ENST00000593812;ENST00000593404;ENST00000358726;ENST00000597244;ENST00000593962;ENST00000600740;ENST00000551747;ENST00000597781;ENST00000593779;ENST00000600356","GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0006396(RNA processing);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005783(endoplasmic reticulum);GO:0005515(protein binding);GO:0048471(perinuclear region of cytoplasm);GO:0005654(nucleoplasm);GO:0044325(ion channel binding);GO:0007399(nervous system development);GO:0033017(sarcoplasmic reticulum membrane);GO:0000398(mRNA splicing, via spliceosome);GO:0051209(release of sequestered calcium ion into cytosol);GO:0008285(negative regulation of cell proliferation);GO:0051533(positive regulation of NFAT protein import into nucleus);GO:0006874(cellular calcium ion homeostasis);GO:0016021(integral component of membrane);GO:0006810(transport);GO:0005794(Golgi apparatus);GO:0005634(nucleus);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0003713(transcription coactivator activity);GO:0006367(transcription initiation from RNA polymerase II promoter);GO:0001104(RNA polymerase II transcription cofactor activity);GO:0016592(mediator complex);GO:0005794(Golgi apparatus)","03040(Spliceosome);03040(Spliceosome)","K12841","NA","calcium homeostasis endoplasmic reticulum protein [Source:HGNC Symbol;Acc:HGNC:16930];small integral membrane protein 7 [Source:HGNC Symbol;Acc:HGNC:28419];solute carrier family 35 member E1 [Source:HGNC Symbol;Acc:HGNC:20803];mediator complex subunit 26 [Source:HGNC Symbol;Acc:HGNC:2376]",{"v":2.53170653342162,"d":"2.53"},{"v":2.7561410900195,"d":"2.76"},{"v":0.918569278833149,"d":"0.92"},{"v":-0.122539560856278,"d":"-0.12"},{"v":0.885143927259181,"d":"0.89"},1,"down","no"]
["MSTRG.10990","SELENOK","ENST00000495461;ENST00000541726;ENST00000485414;ENST00000488746;ENST00000487571","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0006811(ion transport);GO:0005886(plasma membrane);GO:0006816(calcium ion transport);GO:0042802(identical protein binding);GO:0005794(Golgi apparatus);GO:0006979(response to oxidative stress);GO:0070059(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress);GO:0002376(immune system process);GO:0002230(positive regulation of defense response to virus by host);GO:0010742(macrophage derived foam cell differentiation);GO:0018345(protein palmitoylation);GO:0030335(positive regulation of cell migration);GO:0032469(endoplasmic reticulum calcium ion homeostasis);GO:0032760(positive regulation of tumor necrosis factor production);GO:0042102(positive regulation of T cell proliferation);GO:0045728(respiratory burst after phagocytosis);GO:0050848(regulation of calcium-mediated signaling);GO:0051223(regulation of protein transport);GO:0071639(positive regulation of monocyte chemotactic protein-1 production);GO:0090197(positive regulation of chemokine secretion);GO:2000406(positive regulation of T cell migration);GO:2000778(positive regulation of interleukin-6 secretion);GO:2000778(positive regulation of interleukin-6 secretion)","NA","NA","NA","selenoprotein K [Source:HGNC Symbol;Acc:HGNC:30394]",{"v":3.28907236905312,"d":"3.29"},{"v":3.58547546327945,"d":"3.59"},{"v":0.917332276496678,"d":"0.92"},{"v":-0.124483692774764,"d":"-0.12"},{"v":0.886946776264432,"d":"0.89"},1,"down","no"]
["ENSG00000123575","FAM199X","ENST00000493442;ENST00000299906","GO:0005515(protein binding);GO:0005515(protein binding)","NA","NA","NA","family with sequence similarity 199, X-linked [Source:HGNC Symbol;Acc:HGNC:25195]",{"v":2.153133,"d":"2.15"},{"v":2.340877,"d":"2.34"},{"v":0.919797580137701,"d":"0.92"},{"v":-0.120611692698904,"d":"-0.12"},{"v":0.88712888315136,"d":"0.89"},1,"down","no"]
["MSTRG.4197","TRAV20","ENST00000390448","NA","NA","NA","NA","T-cell receptor alpha variable 20 [Source:HGNC Symbol;Acc:HGNC:12117]",{"v":2.734689,"d":"2.73"},{"v":2.567747,"d":"2.57"},{"v":1.06501497226946,"d":"1.07"},{"v":0.0908737123920283,"d":"0.09"},{"v":0.888316906537219,"d":"0.89"},1,"up","no"]
["MSTRG.10039","CRYZL1","ENST00000381554;ENST00000381540;ENST00000414079;ENST00000426935;ENST00000488167;ENST00000440526;ENST00000361534;ENST00000420072;ENST00000490714;ENST00000399442;ENST00000468349;ENST00000479964;ENST00000417979","GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0005829(cytosol);GO:0050661(NADP binding);GO:0003960(NADPH:quinone reductase activity);GO:1901661(quinone metabolic process);GO:1901661(quinone metabolic process)","NA","NA","NA","crystallin zeta like 1 [Source:HGNC Symbol;Acc:HGNC:2420]",{"v":0.813249118018456,"d":"0.81"},{"v":0.886900140359398,"d":"0.89"},{"v":0.916956803827885,"d":"0.92"},{"v":-0.125074322213312,"d":"-0.13"},{"v":0.888585002382631,"d":"0.89"},1,"down","no"]
["MSTRG.3065","ZNF384","ENST00000436774;ENST00000417772;ENST00000396801;ENST00000319770;ENST00000361959;ENST00000537248;ENST00000544482;ENST00000535485;ENST00000542519;ENST00000542351;ENST00000355772;ENST00000542605;ENST00000537383;ENST00000540915","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0003677(DNA binding)","NA","NA","NA","zinc finger protein 384 [Source:HGNC Symbol;Acc:HGNC:11955]",{"v":4.78880995657209,"d":"4.79"},{"v":4.57920223624783,"d":"4.58"},{"v":1.04577385088281,"d":"1.05"},{"v":0.0645709017906659,"d":"0.06"},{"v":0.889767903812168,"d":"0.89"},1,"up","no"]
["MSTRG.15368","PBDC1","ENST00000373358;ENST00000373357","GO:0005737(cytoplasm);GO:0003674(molecular_function);GO:0008150(biological_process);GO:0005575(cellular_component);GO:0005575(cellular_component)","NA","NA","NA","polysaccharide biosynthesis domain containing 1 [Source:HGNC Symbol;Acc:HGNC:28790]",{"v":5.4495264937552,"d":"5.45"},{"v":5.21505041798501,"d":"5.22"},{"v":1.04496142069146,"d":"1.04"},{"v":0.0634496799094753,"d":"0.06"},{"v":0.891622606077162,"d":"0.89"},1,"up","no"]
["MSTRG.1313","ADIPOR1","ENST00000426229;ENST00000340990;ENST00000367254;ENST00000495562","GO:0010719(negative regulation of epithelial to mesenchymal transition);GO:1901223(negative regulation of NIK/NF-kappaB signaling);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0046872(metal ion binding);GO:0006629(lipid metabolic process);GO:0006631(fatty acid metabolic process);GO:0005886(plasma membrane);GO:0007186(G-protein coupled receptor signaling pathway);GO:0009755(hormone-mediated signaling pathway);GO:0031226(intrinsic component of plasma membrane);GO:0019216(regulation of lipid metabolic process);GO:0046426(negative regulation of JAK-STAT cascade);GO:0019901(protein kinase binding);GO:0042593(glucose homeostasis);GO:0042304(regulation of fatty acid biosynthetic process);GO:0010906(regulation of glucose metabolic process);GO:0019395(fatty acid oxidation);GO:0010633(negative regulation of epithelial cell migration);GO:0055100(adiponectin binding);GO:0097003(adipokinetic hormone receptor activity);GO:0033211(adiponectin-activated signaling pathway);GO:0004872(receptor activity);GO:0042802(identical protein binding);GO:0046982(protein heterodimerization activity);GO:0030308(negative regulation of cell growth);GO:0033210(leptin-mediated signaling pathway);GO:0046427(positive regulation of JAK-STAT cascade);GO:0046628(positive regulation of insulin receptor signaling pathway);GO:0046628(positive regulation of insulin receptor signaling pathway)","04152(AMPK signaling pathway);04920(Adipocytokine signaling pathway);04211(Longevity regulating pathway - mammal);04932(Non-alcoholic fatty liver disease (NAFLD));04932(Non-alcoholic fatty liver disease (NAFLD))","K07297","NA","adiponectin receptor 1 [Source:HGNC Symbol;Acc:HGNC:24040]",{"v":191.440903141246,"d":"191.44"},{"v":183.337593339179,"d":"183.34"},{"v":1.0441988446258,"d":"1.04"},{"v":0.0623964675012683,"d":"0.06"},{"v":0.891935638143853,"d":"0.89"},1,"up","no"]
["ENSG00000184517","ZFP1","ENST00000332307;ENST00000393430;ENST00000566105;ENST00000567481;ENST00000570010","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0005622(intracellular);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding)","NA","NA","NA","ZFP1 zinc finger protein [Source:HGNC Symbol;Acc:HGNC:23328]",{"v":0.903684923424621,"d":"0.90"},{"v":0.862134624036161,"d":"0.86"},{"v":1.04819467659695,"d":"1.05"},{"v":0.0679066871788345,"d":"0.07"},{"v":0.89330206797093,"d":"0.89"},1,"up","no"]
["MSTRG.8278","KDELR1","ENST00000330720;ENST00000600980;ENST00000599084;ENST00000594643;ENST00000597017","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0015031(protein transport);GO:0046923(ER retention sequence binding);GO:0006621(protein retention in ER lumen);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0031410(cytoplasmic vesicle);GO:0016192(vesicle-mediated transport);GO:0030663(COPI-coated vesicle membrane);GO:0006890(retrograde vesicle-mediated transport, Golgi to ER);GO:0006886(intracellular protein transport);GO:0006888(ER to Golgi vesicle-mediated transport);GO:0000139(Golgi membrane);GO:0030133(transport vesicle);GO:0033116(endoplasmic reticulum-Golgi intermediate compartment membrane);GO:0005793(endoplasmic reticulum-Golgi intermediate compartment);GO:0005046(KDEL sequence binding);GO:0002369(T cell cytokine production);GO:0030217(T cell differentiation);GO:0070231(T cell apoptotic process);GO:0005794(Golgi apparatus);GO:0005801(cis-Golgi network);GO:0005801(cis-Golgi network)","05110(Vibrio cholerae infection);05110(Vibrio cholerae infection)","K10949","NA","KDEL endoplasmic reticulum protein retention receptor 1 [Source:HGNC Symbol;Acc:HGNC:6304]",{"v":10.2542076166148,"d":"10.25"},{"v":9.82644687916482,"d":"9.83"},{"v":1.04353157786432,"d":"1.04"},{"v":0.061474257938052,"d":"0.06"},{"v":0.894067046319569,"d":"0.89"},1,"up","no"]
["ENSG00000140543","DET1","ENST00000268148;ENST00000564406;ENST00000606927;ENST00000557842;ENST00000444300","GO:0005634(nucleus);GO:0016567(protein ubiquitination);GO:0005515(protein binding);GO:0031625(ubiquitin protein ligase binding);GO:0032403(protein complex binding);GO:0006461(protein complex assembly);GO:0032436(positive regulation of proteasomal ubiquitin-dependent protein catabolic process);GO:0031464(Cul4A-RING E3 ubiquitin ligase complex);GO:1990756(protein binding, bridging involved in substrate recognition for ubiquitination);GO:1990756(protein binding, bridging involved in substrate recognition for ubiquitination)","04120(Ubiquitin mediated proteolysis);04120(Ubiquitin mediated proteolysis)","K10571","NA","de-etiolated homolog 1 (Arabidopsis) [Source:HGNC Symbol;Acc:HGNC:25477]",{"v":0.415065880928061,"d":"0.42"},{"v":0.455105627608347,"d":"0.46"},{"v":0.912020980951826,"d":"0.91"},{"v":-0.132861081059866,"d":"-0.13"},{"v":0.895790722710564,"d":"0.90"},1,"down","no"]
["ENSG00000100209","HSCB","ENST00000398941;ENST00000485599;ENST00000420442;ENST00000483861;ENST00000216027;ENST00000495977","GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0005634(nucleus);GO:0005829(cytosol);GO:0005739(mitochondrion);GO:0005515(protein binding);GO:0032781(positive regulation of ATPase activity);GO:0051087(chaperone binding);GO:0016226(iron-sulfur cluster assembly);GO:0097428(protein maturation by iron-sulfur cluster transfer);GO:0001671(ATPase activator activity);GO:0003674(molecular_function);GO:0051259(protein oligomerization);GO:0051259(protein oligomerization)","NA","NA","NA","HscB mitochondrial iron-sulfur cluster cochaperone [Source:HGNC Symbol;Acc:HGNC:28913]",{"v":0.888560649794802,"d":"0.89"},{"v":0.973304663474692,"d":"0.97"},{"v":0.912931667893839,"d":"0.91"},{"v":-0.131421215050265,"d":"-0.13"},{"v":0.896535785174037,"d":"0.90"},1,"down","no"]
["MSTRG.9224","PPIG","ENST00000260970;ENST00000466142;ENST00000462903;ENST00000433207;ENST00000418888;ENST00000417938;ENST00000409714;ENST00000482772;ENST00000448752;ENST00000414307","GO:0003723(RNA binding);GO:0005634(nucleus);GO:0016607(nuclear speck);GO:0016853(isomerase activity);GO:0005829(cytosol);GO:0003755(peptidyl-prolyl cis-trans isomerase activity);GO:0000413(protein peptidyl-prolyl isomerization);GO:0006457(protein folding);GO:0005515(protein binding);GO:0016363(nuclear matrix);GO:0005654(nucleoplasm);GO:0008380(RNA splicing);GO:0016018(cyclosporin A binding);GO:0016018(cyclosporin A binding)","NA","NA","NA","peptidylprolyl isomerase G [Source:HGNC Symbol;Acc:HGNC:14650]",{"v":5.34302562296417,"d":"5.34"},{"v":5.76866247502714,"d":"5.77"},{"v":0.926215677567274,"d":"0.93"},{"v":-0.110579917896353,"d":"-0.11"},{"v":0.897414499113237,"d":"0.90"},1,"down","no"]
["MSTRG.5335","PSMA4","ENST00000559365;ENST00000559082;ENST00000560737;ENST00000044462;ENST00000558341;ENST00000560217;ENST00000558281;ENST00000559146;ENST00000559154;ENST00000558635;ENST00000558094;ENST00000559934;ENST00000560842;ENST00000558639;ENST00000559437;ENST00000560033;ENST00000559906;ENST00000560099;ENST00000413382","GO:0005737(cytoplasm);GO:0016787(hydrolase activity);GO:0008233(peptidase activity);GO:0006508(proteolysis);GO:0000502(proteasome complex);GO:0004298(threonine-type endopeptidase activity);GO:0051603(proteolysis involved in cellular protein catabolic process);GO:0005839(proteasome core complex);GO:0019773(proteasome core complex, alpha-subunit complex);GO:0005634(nucleus);GO:0043231(intracellular membrane-bounded organelle);GO:0005829(cytosol);GO:0005515(protein binding);GO:0006511(ubiquitin-dependent protein catabolic process);GO:0004175(endopeptidase activity);GO:0038095(Fc-epsilon receptor signaling pathway);GO:0000932(P-body);GO:0005654(nucleoplasm);GO:0070062(extracellular exosome);GO:0000165(MAPK cascade);GO:0000209(protein polyubiquitination);GO:0002223(stimulatory C-type lectin receptor signaling pathway);GO:0002479(antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent);GO:0006521(regulation of cellular amino acid metabolic process);GO:0010972(negative regulation of G2/M transition of mitotic cell cycle);GO:0016579(protein deubiquitination);GO:0031145(anaphase-promoting complex-dependent catabolic process);GO:0031146(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process);GO:0033209(tumor necrosis factor-mediated signaling pathway);GO:0038061(NIK/NF-kappaB signaling);GO:0043161(proteasome-mediated ubiquitin-dependent protein catabolic process);GO:0043488(regulation of mRNA stability);GO:0043687(post-translational protein modification);GO:0050852(T cell receptor signaling pathway);GO:0051437(positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition);GO:0055085(transmembrane transport);GO:0060071(Wnt signaling pathway, planar cell polarity pathway);GO:0061418(regulation of transcription from RNA polymerase II promoter in response to hypoxia);GO:0090090(negative regulation of canonical Wnt signaling pathway);GO:0090263(positive regulation of canonical Wnt signaling pathway);GO:1902036(regulation of hematopoietic stem cell differentiation);GO:0016032(viral process);GO:0051436(negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle);GO:0051436(negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle)","03050(Proteasome);03050(Proteasome)","K02728","EC:3.4.25.1","proteasome subunit alpha 4 [Source:HGNC Symbol;Acc:HGNC:9533]",{"v":4.84352648170383,"d":"4.84"},{"v":5.23200120697541,"d":"5.23"},{"v":0.925750260769501,"d":"0.93"},{"v":-0.111305044105566,"d":"-0.11"},{"v":0.898319836457421,"d":"0.90"},1,"down","no"]
["MSTRG.4915","PWAR6","ENST00000552334","NA","NA","NA","NA","Prader Willi/Angelman region RNA 6 [Source:HGNC Symbol;Acc:HGNC:49129]",{"v":0.314148,"d":"0.31"},{"v":0.296881,"d":"0.30"},{"v":1.05816135084428,"d":"1.06"},{"v":0.0815596296396175,"d":"0.08"},{"v":0.899071407656446,"d":"0.90"},1,"up","no"]
["ENSG00000103253","HAGHL","ENST00000568141;ENST00000341413;ENST00000569143;ENST00000549114;ENST00000564537;ENST00000569604;ENST00000389701;ENST00000561546;ENST00000563792;ENST00000561750;ENST00000569385;ENST00000561561;ENST00000567696;ENST00000389703","GO:0046872(metal ion binding);GO:0016787(hydrolase activity);GO:0004416(hydroxyacylglutathione hydrolase activity);GO:0019243(methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione);GO:0019243(methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione)","NA","NA","NA","hydroxyacylglutathione hydrolase like [Source:HGNC Symbol;Acc:HGNC:14177]",{"v":0.206314190184049,"d":"0.21"},{"v":0.193705915132924,"d":"0.19"},{"v":1.06508977819533,"d":"1.07"},{"v":0.0909750427498831,"d":"0.09"},{"v":0.901097449728149,"d":"0.90"},1,"up","no"]
["ENSG00000143869","GDF7","ENST00000272224","GO:0030509(BMP signaling pathway);GO:0008083(growth factor activity);GO:0005576(extracellular region);GO:0005125(cytokine activity);GO:0005615(extracellular space);GO:0005515(protein binding);GO:0060395(SMAD protein signal transduction);GO:0045893(positive regulation of transcription, DNA-templated);GO:0005160(transforming growth factor beta receptor binding);GO:0042981(regulation of apoptotic process);GO:0043408(regulation of MAPK cascade);GO:0048468(cell development);GO:0060389(pathway-restricted SMAD protein phosphorylation);GO:0010862(positive regulation of pathway-restricted SMAD protein phosphorylation);GO:0032924(activin receptor signaling pathway);GO:0042803(protein homodimerization activity);GO:0007411(axon guidance);GO:0010628(positive regulation of gene expression);GO:0021509(roof plate formation);GO:0021527(spinal cord association neuron differentiation);GO:0021915(neural tube development);GO:0022612(gland morphogenesis);GO:0030855(epithelial cell differentiation);GO:0030901(midbrain development);GO:0045165(cell fate commitment);GO:0045666(positive regulation of neuron differentiation);GO:0048608(reproductive structure development);GO:0048754(branching morphogenesis of an epithelial tube);GO:0048853(forebrain morphogenesis);GO:0060571(morphogenesis of an epithelial fold);GO:2001051(positive regulation of tendon cell differentiation)","04350(TGF-beta signaling pathway);04390(Hippo signaling pathway);04360(Axon guidance)","K20013","NA","growth differentiation factor 7 [Source:HGNC Symbol;Acc:HGNC:4222]",{"v":0.17513,"d":"0.18"},{"v":0.16665,"d":"0.17"},{"v":1.05088508850885,"d":"1.05"},{"v":0.0716049230564995,"d":"0.07"},{"v":0.901257612788831,"d":"0.90"},1,"up","no"]
["MSTRG.9071","DBI","ENST00000355857;ENST00000492375;ENST00000409094;ENST00000542275;ENST00000475783;ENST00000627305;ENST00000535757;ENST00000393103;ENST00000460901;ENST00000627093","GO:0006810(transport);GO:0005794(Golgi apparatus);GO:0005783(endoplasmic reticulum);GO:0000062(fatty-acyl-CoA binding);GO:0008289(lipid binding);GO:0070062(extracellular exosome);GO:0006637(acyl-CoA metabolic process);GO:0005788(endoplasmic reticulum lumen);GO:0046983(protein dimerization activity);GO:0030156(benzodiazepine receptor binding);GO:0036042(long-chain fatty acyl-CoA binding);GO:0036151(phosphatidylcholine acyl-chain remodeling);GO:0036151(phosphatidylcholine acyl-chain remodeling)","03320(PPAR signaling pathway);03320(PPAR signaling pathway)","K08762","NA","diazepam binding inhibitor, acyl-CoA binding protein [Source:HGNC Symbol;Acc:HGNC:2690]",{"v":15.6031169693105,"d":"15.60"},{"v":15.023462565564,"d":"15.02"},{"v":1.03858327607346,"d":"1.04"},{"v":0.0546168995349411,"d":"0.05"},{"v":0.902248277085293,"d":"0.90"},1,"up","no"]
["ENSG00000088827","SIGLEC1","ENST00000419548;ENST00000344754","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0030246(carbohydrate binding);GO:0007155(cell adhesion);GO:0005886(plasma membrane);GO:0005576(extracellular region);GO:0006954(inflammatory response);GO:0006897(endocytosis);GO:0007160(cell-matrix adhesion);GO:0016337(single organismal cell-cell adhesion);GO:0016337(single organismal cell-cell adhesion)","04514(Cell adhesion molecules (CAMs));04514(Cell adhesion molecules (CAMs))","K06548","NA","sialic acid binding Ig like lectin 1 [Source:HGNC Symbol;Acc:HGNC:11127]",{"v":0.499626892467664,"d":"0.50"},{"v":0.539424656606645,"d":"0.54"},{"v":0.926221829774455,"d":"0.93"},{"v":-0.110570335107453,"d":"-0.11"},{"v":0.902894307664507,"d":"0.90"},1,"down","no"]
["MSTRG.4721","ZFYVE21","ENST00000311141;ENST00000556610;ENST00000553724;ENST00000554757;ENST00000554255;ENST00000555163;ENST00000556795;ENST00000216602;ENST00000555501;ENST00000602552;ENST00000554630","GO:0005829(cytosol);GO:0046872(metal ion binding);GO:0005515(protein binding);GO:0030054(cell junction);GO:0031410(cytoplasmic vesicle);GO:0005925(focal adhesion);GO:0005768(endosome);GO:0042147(retrograde transport, endosome to Golgi);GO:0046854(phosphatidylinositol phosphorylation);GO:0010008(endosome membrane);GO:0000285(1-phosphatidylinositol-3-phosphate 5-kinase activity);GO:0000285(1-phosphatidylinositol-3-phosphate 5-kinase activity)","NA","NA","NA","zinc finger FYVE-type containing 21 [Source:HGNC Symbol;Acc:HGNC:20760]",{"v":0.852782439928486,"d":"0.85"},{"v":0.91625975363528,"d":"0.92"},{"v":0.930721268226672,"d":"0.93"},{"v":-0.103578919751157,"d":"-0.10"},{"v":0.903822008174112,"d":"0.90"},1,"down","no"]
["MSTRG.279","UBXN11","ENST00000374221;ENST00000374223;ENST00000472155;ENST00000357089;ENST00000475591;ENST00000374222;ENST00000496466;ENST00000450041;ENST00000423664;ENST00000494942;ENST00000374215;ENST00000421827;ENST00000442942;ENST00000314675;ENST00000374217","GO:0005737(cytoplasm);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0043161(proteasome-mediated ubiquitin-dependent protein catabolic process);GO:0043130(ubiquitin binding);GO:0043130(ubiquitin binding)","NA","NA","NA","UBX domain protein 11 [Source:HGNC Symbol;Acc:HGNC:30600]",{"v":5.9890637372449,"d":"5.99"},{"v":6.44675617857143,"d":"6.45"},{"v":0.929004226521259,"d":"0.93"},{"v":-0.106242934697744,"d":"-0.11"},{"v":0.904975451192585,"d":"0.90"},1,"down","no"]
["ENSG00000206053","JPT2","ENST00000248098;ENST00000382710;ENST00000562569;ENST00000566742;ENST00000561516;ENST00000566691;ENST00000566925;ENST00000569765;ENST00000567717;ENST00000565851;ENST00000569256;ENST00000562684","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0005886(plasma membrane)","NA","NA","NA","Jupiter microtubule associated homolog 2 [Source:HGNC Symbol;Acc:HGNC:14137]",{"v":0.976556061451342,"d":"0.98"},{"v":1.0530344175755,"d":"1.05"},{"v":0.927373355658933,"d":"0.93"},{"v":-0.108777817615212,"d":"-0.11"},{"v":0.905307352514265,"d":"0.91"},1,"down","no"]
["MSTRG.3607","TMCC3","ENST00000261226;ENST00000551457;ENST00000548918","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005515(protein binding);GO:0005515(protein binding)","NA","NA","NA","transmembrane and coiled-coil domain family 3 [Source:HGNC Symbol;Acc:HGNC:29199]",{"v":2.85073282455871,"d":"2.85"},{"v":2.74861566600153,"d":"2.75"},{"v":1.03715221441117,"d":"1.04"},{"v":0.0526276423295126,"d":"0.05"},{"v":0.906583099714753,"d":"0.91"},1,"up","no"]
["ENSG00000123104","ITPR2","ENST00000381340;ENST00000543958;ENST00000536627;ENST00000540429;ENST00000451599","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0055085(transmembrane transport);GO:0005783(endoplasmic reticulum);GO:0005634(nucleus);GO:0005216(ion channel activity);GO:0006811(ion transport);GO:0005789(endoplasmic reticulum membrane);GO:0006816(calcium ion transport);GO:0070588(calcium ion transmembrane transport);GO:0005262(calcium channel activity);GO:0005509(calcium ion binding);GO:0005220(inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity);GO:0048016(inositol phosphate-mediated signaling);GO:1903779(regulation of cardiac conduction);GO:0007165(signal transduction);GO:0005886(plasma membrane);GO:0030168(platelet activation);GO:0050796(regulation of insulin secretion);GO:0051209(release of sequestered calcium ion into cytosol);GO:0031095(platelet dense tubular network membrane);GO:0033017(sarcoplasmic reticulum membrane);GO:0043235(receptor complex);GO:0001666(response to hypoxia);GO:0015085(calcium ion transmembrane transporter activity);GO:0015278(calcium-release channel activity);GO:0035091(phosphatidylinositol binding);GO:0071320(cellular response to cAMP);GO:0071361(cellular response to ethanol);GO:0005737(cytoplasm);GO:0005938(cell cortex);GO:0016529(sarcoplasmic reticulum);GO:0016529(sarcoplasmic reticulum)","04371(Apelin signaling pathway);04020(Calcium signaling pathway);04070(Phosphatidylinositol signaling system);04022(cGMP - PKG signaling pathway);04114(Oocyte meiosis);04210(Apoptosis);04218(Cellular senescence);04540(Gap junction);04611(Platelet activation);04621(NOD-like receptor signaling pathway);04922(Glucagon signaling pathway);04912(GnRH signaling pathway);04915(Estrogen signaling pathway);04921(Oxytocin signaling pathway);04918(Thyroid hormone synthesis);04924(Renin secretion);04925(Aldosterone synthesis and secretion);04927(Cortisol synthesis and secretion);04270(Vascular smooth muscle contraction);04970(Salivary secretion);04971(Gastric acid secretion);04972(Pancreatic secretion);04724(Glutamatergic synapse);04725(Cholinergic synapse);04728(Dopaminergic synapse);04726(Serotonergic synapse);04720(Long-term potentiation);04730(Long-term depression);04723(Retrograde endocannabinoid signaling);04750(Inflammatory mediator regulation of TRP channels);05205(Proteoglycans in cancer);05010(Alzheimer's disease);05167(Kaposi's sarcoma-associated herpesvirus infection);05167(Kaposi's sarcoma-associated herpesvirus infection)","K04959","NA","inositol 1,4,5-trisphosphate receptor type 2 [Source:HGNC Symbol;Acc:HGNC:6181]",{"v":1.57542397294118,"d":"1.58"},{"v":1.52023715913725,"d":"1.52"},{"v":1.03630145038373,"d":"1.04"},{"v":0.0514437305469028,"d":"0.05"},{"v":0.907209015733496,"d":"0.91"},1,"up","no"]
["MSTRG.2322","PDHX","ENST00000532159;ENST00000448838;ENST00000477173;ENST00000430469;ENST00000533550;ENST00000227868","GO:0016746(transferase activity, transferring acyl groups);GO:0008152(metabolic process);GO:0005739(mitochondrion);GO:0005515(protein binding);GO:0005759(mitochondrial matrix);GO:0034641(cellular nitrogen compound metabolic process);GO:0034604(pyruvate dehydrogenase (NAD+) activity);GO:0006090(pyruvate metabolic process);GO:0010510(regulation of acetyl-CoA biosynthetic process from pyruvate);GO:0061732(mitochondrial acetyl-CoA biosynthetic process from pyruvate);GO:0045254(pyruvate dehydrogenase complex);GO:0045254(pyruvate dehydrogenase complex)","00010(Glycolysis / Gluconeogenesis);00020(Citrate cycle (TCA cycle));00620(Pyruvate metabolism);00620(Pyruvate metabolism)","K13997","NA","pyruvate dehydrogenase complex component X [Source:HGNC Symbol;Acc:HGNC:21350]",{"v":1.28553706303191,"d":"1.29"},{"v":1.38511737180851,"d":"1.39"},{"v":0.928106952664538,"d":"0.93"},{"v":-0.107637027478669,"d":"-0.11"},{"v":0.908216173030666,"d":"0.91"},1,"down","no"]
["MSTRG.12344","AC106791.1","ENST00000514616;ENST00000508281","NA","NA","NA","NA",null,{"v":0.362320451343284,"d":"0.36"},{"v":0.397383112835821,"d":"0.40"},{"v":0.911766100873483,"d":"0.91"},{"v":-0.133264323555775,"d":"-0.13"},{"v":0.908721162293809,"d":"0.91"},1,"down","no"]
["MSTRG.5533","ECI1","ENST00000566379;ENST00000561688;ENST00000570258;ENST00000563029;ENST00000562238;ENST00000563447","GO:0016853(isomerase activity);GO:0003824(catalytic activity);GO:0006629(lipid metabolic process);GO:0008152(metabolic process);GO:0006631(fatty acid metabolic process);GO:0005739(mitochondrion);GO:0005759(mitochondrial matrix);GO:0070062(extracellular exosome);GO:0006635(fatty acid beta-oxidation);GO:0004165(dodecenoyl-CoA delta-isomerase activity);GO:0004300(enoyl-CoA hydratase activity);GO:0016860(intramolecular oxidoreductase activity);GO:0005743(mitochondrial inner membrane);GO:0005743(mitochondrial inner membrane)","00071(Fatty acid degradation);00071(Fatty acid degradation)","K13238","EC:5.3.3.8","enoyl-CoA delta isomerase 1 [Source:HGNC Symbol;Acc:HGNC:2703]",{"v":0.789389186456401,"d":"0.79"},{"v":0.759868659554731,"d":"0.76"},{"v":1.03884951238674,"d":"1.04"},{"v":0.054986680750594,"d":"0.05"},{"v":0.909586998675521,"d":"0.91"},1,"up","no"]
["MSTRG.14017","NDUFB2;ADCK2","ENST00000247866;ENST00000072869;ENST00000482954;ENST00000476491;ENST00000464566;ENST00000472695;ENST00000479181;ENST00000460088;ENST00000476279;ENST00000465506;ENST00000461457;ENST00000475276;ENST00000471136;ENST00000476470;ENST00000476181;ENST00000462847;ENST00000464564","GO:0005743(mitochondrial inner membrane);GO:0005747(mitochondrial respiratory chain complex I);GO:0016020(membrane);GO:0055114(oxidation-reduction process);GO:0005739(mitochondrion);GO:0070469(respiratory chain);GO:0032981(mitochondrial respiratory chain complex I assembly);GO:0008137(NADH dehydrogenase (ubiquinone) activity);GO:0006120(mitochondrial electron transport, NADH to ubiquinone);GO:0016021(integral component of membrane);GO:0000166(nucleotide binding);GO:0004674(protein serine/threonine kinase activity);GO:0005524(ATP binding);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0006468(protein phosphorylation);GO:0004672(protein kinase activity);GO:0006120(mitochondrial electron transport, NADH to ubiquinone)","00190(Oxidative phosphorylation);04723(Retrograde endocannabinoid signaling);05010(Alzheimer's disease);05012(Parkinson's disease);05016(Huntington's disease);04932(Non-alcoholic fatty liver disease (NAFLD));04932(Non-alcoholic fatty liver disease (NAFLD))","K03958","NA","NADH:ubiquinone oxidoreductase subunit B2 [Source:HGNC Symbol;Acc:HGNC:7697];aarF domain containing kinase 2 [Source:HGNC Symbol;Acc:HGNC:19039]",{"v":1.56658917297149,"d":"1.57"},{"v":1.51334506716009,"d":"1.51"},{"v":1.03518305703491,"d":"1.04"},{"v":0.0498859098737568,"d":"0.05"},{"v":0.911235125544902,"d":"0.91"},1,"up","no"]
["MSTRG.9197","PSMD14","ENST00000409682;ENST00000492908;ENST00000478123;ENST00000477232;ENST00000437630","GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0016787(hydrolase activity);GO:0005515(protein binding);GO:0008233(peptidase activity);GO:0006508(proteolysis);GO:0006281(DNA repair);GO:0006974(cellular response to DNA damage stimulus);GO:0000502(proteasome complex);GO:0036459(thiol-dependent ubiquitinyl hydrolase activity);GO:0006511(ubiquitin-dependent protein catabolic process);GO:0008237(metallopeptidase activity);GO:0038095(Fc-epsilon receptor signaling pathway);GO:0005576(extracellular region);GO:0061578(Lys63-specific deubiquitinase activity);GO:0045471(response to ethanol);GO:0070536(protein K63-linked deubiquitination);GO:0022624(proteasome accessory complex);GO:0031597(cytosolic proteasome complex);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0000165(MAPK cascade);GO:0000209(protein polyubiquitination);GO:0002223(stimulatory C-type lectin receptor signaling pathway);GO:0002479(antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent);GO:0006521(regulation of cellular amino acid metabolic process);GO:0010972(negative regulation of G2/M transition of mitotic cell cycle);GO:0016579(protein deubiquitination);GO:0031145(anaphase-promoting complex-dependent catabolic process);GO:0031146(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process);GO:0033209(tumor necrosis factor-mediated signaling pathway);GO:0038061(NIK/NF-kappaB signaling);GO:0043161(proteasome-mediated ubiquitin-dependent protein catabolic process);GO:0043488(regulation of mRNA stability);GO:0043687(post-translational protein modification);GO:0050852(T cell receptor signaling pathway);GO:0051437(positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition);GO:0055085(transmembrane transport);GO:0060071(Wnt signaling pathway, planar cell polarity pathway);GO:0061418(regulation of transcription from RNA polymerase II promoter in response to hypoxia);GO:0090090(negative regulation of canonical Wnt signaling pathway);GO:0090263(positive regulation of canonical Wnt signaling pathway);GO:1902036(regulation of hematopoietic stem cell differentiation);GO:0043312(neutrophil degranulation);GO:0051436(negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle);GO:0034774(secretory granule lumen);GO:1904813(ficolin-1-rich granule lumen);GO:0061133(endopeptidase activator activity);GO:0070628(proteasome binding);GO:0000724(double-strand break repair via homologous recombination);GO:0006303(double-strand break repair via nonhomologous end joining);GO:0010950(positive regulation of endopeptidase activity);GO:0061136(regulation of proteasomal protein catabolic process);GO:0008541(proteasome regulatory particle, lid subcomplex);GO:0008541(proteasome regulatory particle, lid subcomplex)","03050(Proteasome);05169(Epstein-Barr virus infection);05169(Epstein-Barr virus infection)","K03030","NA","proteasome 26S subunit, non-ATPase 14 [Source:HGNC Symbol;Acc:HGNC:16889]",{"v":0.652074492205768,"d":"0.65"},{"v":0.702067631852429,"d":"0.70"},{"v":0.928791561697906,"d":"0.93"},{"v":-0.106573229867223,"d":"-0.11"},{"v":0.911560305679456,"d":"0.91"},1,"down","no"]
["MSTRG.9704","PHF20","ENST00000617560;ENST00000374012;ENST00000496305;ENST00000480940;ENST00000449988;ENST00000461122;ENST00000473943;ENST00000485604;ENST00000339089;ENST00000374000;ENST00000461405;ENST00000481202;ENST00000486408;ENST00000452270","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0006366(transcription from RNA polymerase II promoter);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0016569(covalent chromatin modification);GO:0031965(nuclear membrane);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0001228(transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:1901796(regulation of signal transduction by p53 class mediator);GO:0071339(MLL1 complex);GO:0000977(RNA polymerase II regulatory region sequence-specific DNA binding);GO:0043995(histone acetyltransferase activity (H4-K5 specific));GO:0043996(histone acetyltransferase activity (H4-K8 specific));GO:0046972(histone acetyltransferase activity (H4-K16 specific));GO:0043981(histone H4-K5 acetylation);GO:0043982(histone H4-K8 acetylation);GO:0043984(histone H4-K16 acetylation);GO:0000123(histone acetyltransferase complex);GO:0000123(histone acetyltransferase complex)","NA","NA","NA","PHD finger protein 20 [Source:HGNC Symbol;Acc:HGNC:16098]",{"v":3.95305446296075,"d":"3.95"},{"v":3.83382985649529,"d":"3.83"},{"v":1.03109804319132,"d":"1.03"},{"v":0.0441815196128057,"d":"0.04"},{"v":0.913342315220181,"d":"0.91"},1,"up","no"]
["ENSG00000116539","ASH1L","ENST00000368346;ENST00000392403;ENST00000492987;ENST00000548830;ENST00000477427;ENST00000478837;ENST00000548566","GO:0005634(nucleus);GO:0005794(Golgi apparatus);GO:0046872(metal ion binding);GO:0005654(nucleoplasm);GO:0008168(methyltransferase activity);GO:0016740(transferase activity);GO:0032259(methylation);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0016569(covalent chromatin modification);GO:0003677(DNA binding);GO:0005694(chromosome);GO:0030054(cell junction);GO:0003682(chromatin binding);GO:0018024(histone-lysine N-methyltransferase activity);GO:0005923(bicellular tight junction);GO:0070062(extracellular exosome);GO:0007267(cell-cell signaling);GO:0006366(transcription from RNA polymerase II promoter);GO:0006323(DNA packaging);GO:0046975(histone methyltransferase activity (H3-K36 specific));GO:0097676(histone H3-K36 dimethylation);GO:0042800(histone methyltransferase activity (H3-K4 specific));GO:0001501(skeletal system development);GO:0002674(negative regulation of acute inflammatory response);GO:0007338(single fertilization);GO:0009791(post-embryonic development);GO:0010468(regulation of gene expression);GO:0032635(interleukin-6 production);GO:0043124(negative regulation of I-kappaB kinase/NF-kappaB signaling);GO:0043409(negative regulation of MAPK cascade);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0046697(decidualization);GO:0048733(sebaceous gland development);GO:0050728(negative regulation of inflammatory response);GO:0051568(histone H3-K4 methylation);GO:0061038(uterus morphogenesis);GO:0097722(sperm motility);GO:1903699(tarsal gland development);GO:1903709(uterine gland development);GO:1903709(uterine gland development)","00310(Lysine degradation);00310(Lysine degradation)","K06101","EC:2.1.1.43","ASH1 like histone lysine methyltransferase [Source:HGNC Symbol;Acc:HGNC:19088]",{"v":2.79044576790012,"d":"2.79"},{"v":2.98273266952467,"d":"2.98"},{"v":0.935533310246274,"d":"0.94"},{"v":-0.0961390724511707,"d":"-0.10"},{"v":0.914738888937708,"d":"0.91"},1,"down","no"]
["MSTRG.14247","SDAD1P1","ENST00000519902","NA","NA","NA","NA","SDA1 domain containing 1 pseudogene 1 [Source:HGNC Symbol;Acc:HGNC:31403]",{"v":0.209168,"d":"0.21"},{"v":0.22649,"d":"0.23"},{"v":0.923519802198772,"d":"0.92"},{"v":-0.114785198944748,"d":"-0.11"},{"v":0.915985526164835,"d":"0.92"},1,"down","no"]
["MSTRG.8800","TIA1;C2orf42","ENST00000282574;ENST00000474699;ENST00000433529;ENST00000264434;ENST00000495353;ENST00000454815;ENST00000417865;ENST00000428751;ENST00000496096;ENST00000474809;ENST00000477044;ENST00000495774;ENST00000425268;ENST00000497672;ENST00000428010;ENST00000481650;ENST00000482876;ENST00000416149;ENST00000470096;ENST00000484065;ENST00000486392;ENST00000447804;ENST00000457952;ENST00000477415;ENST00000468787;ENST00000415783;ENST00000417203;ENST00000496452","GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0006915(apoptotic process);GO:0005515(protein binding);GO:0005737(cytoplasm);GO:1903608(protein localization to cytoplasmic stress granule);GO:0008543(fibroblast growth factor receptor signaling pathway);GO:0048024(regulation of mRNA splicing, via spliceosome);GO:0010494(cytoplasmic stress granule);GO:0008143(poly(A) binding);GO:0017091(AU-rich element binding);GO:0017148(negative regulation of translation);GO:0042036(negative regulation of cytokine biosynthetic process);GO:1904037(positive regulation of epithelial cell apoptotic process);GO:0030529(intracellular ribonucleoprotein complex);GO:0097165(nuclear stress granule);GO:0031965(nuclear membrane);GO:0097165(nuclear stress granule)","NA","NA","NA","TIA1 cytotoxic granule associated RNA binding protein [Source:HGNC Symbol;Acc:HGNC:11802];chromosome 2 open reading frame 42 [Source:HGNC Symbol;Acc:HGNC:26056]",{"v":3.13738388649511,"d":"3.14"},{"v":3.35804959555157,"d":"3.36"},{"v":0.934287537221375,"d":"0.93"},{"v":-0.0980614714162491,"d":"-0.10"},{"v":0.917036242939973,"d":"0.92"},1,"down","no"]
["MSTRG.4182","ACIN1","ENST00000473758;ENST00000262710;ENST00000605057;ENST00000553721;ENST00000555053;ENST00000457657;ENST00000557039;ENST00000553501;ENST00000338631;ENST00000555807;ENST00000556052;ENST00000555566;ENST00000555352;ENST00000553790;ENST00000554708;ENST00000555395;ENST00000554979;ENST00000357481;ENST00000397341;ENST00000557432;ENST00000554680;ENST00000557515;ENST00000555478","GO:0003676(nucleic acid binding);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0005886(plasma membrane);GO:0003723(RNA binding);GO:0006397(mRNA processing);GO:0008380(RNA splicing);GO:0005634(nucleus);GO:0016607(nuclear speck);GO:0005515(protein binding);GO:0006915(apoptotic process);GO:0030218(erythrocyte differentiation);GO:0016887(ATPase activity);GO:0019899(enzyme binding);GO:0061574(ASAP complex);GO:0097194(execution phase of apoptosis);GO:0030263(apoptotic chromosome condensation);GO:0045657(positive regulation of monocyte differentiation);GO:0005730(nucleolus);GO:0005730(nucleolus)","03040(Spliceosome);03013(RNA transport);03015(mRNA surveillance pathway);03015(mRNA surveillance pathway)","K12875","NA","apoptotic chromatin condensation inducer 1 [Source:HGNC Symbol;Acc:HGNC:17066]",{"v":11.1817521020856,"d":"11.18"},{"v":10.8674574145993,"d":"10.87"},{"v":1.02892071949268,"d":"1.03"},{"v":0.0411318238245442,"d":"0.04"},{"v":0.917225881639368,"d":"0.92"},1,"up","no"]
["ENSG00000197933","ZNF823","ENST00000431998;ENST00000341191","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0005622(intracellular);GO:0005622(intracellular)","NA","NA","NA","zinc finger protein 823 [Source:HGNC Symbol;Acc:HGNC:30936]",{"v":0.588633754778365,"d":"0.59"},{"v":0.633829801138674,"d":"0.63"},{"v":0.928693718283497,"d":"0.93"},{"v":-0.10672521837599,"d":"-0.11"},{"v":0.918437348040641,"d":"0.92"},1,"down","no"]
["ENSG00000100379","KCTD17","ENST00000403888;ENST00000462640;ENST00000610767;ENST00000402077;ENST00000421900;ENST00000478231","GO:0005737(cytoplasm);GO:0051260(protein homooligomerization);GO:0005515(protein binding);GO:0042802(identical protein binding);GO:0030030(cell projection organization);GO:0005783(endoplasmic reticulum);GO:0043161(proteasome-mediated ubiquitin-dependent protein catabolic process);GO:0031463(Cul3-RING ubiquitin ligase complex);GO:0045724(positive regulation of cilium assembly);GO:0097602(cullin family protein binding);GO:0032469(endoplasmic reticulum calcium ion homeostasis);GO:0032403(protein complex binding);GO:0032403(protein complex binding)","NA","NA","NA","potassium channel tetramerization domain containing 17 [Source:HGNC Symbol;Acc:HGNC:25705]",{"v":2.54548820603015,"d":"2.55"},{"v":2.47110542785355,"d":"2.47"},{"v":1.0301010136347,"d":"1.03"},{"v":0.0427858177232897,"d":"0.04"},{"v":0.918666604033791,"d":"0.92"},1,"up","no"]
["MSTRG.2381","NUP160","ENST00000378460;ENST00000527126;ENST00000526870;ENST00000528501;ENST00000527750;ENST00000528071;ENST00000531016;ENST00000532773;ENST00000526569","GO:0006810(transport);GO:0051028(mRNA transport);GO:0005634(nucleus);GO:0015031(protein transport);GO:0005515(protein binding);GO:0006406(mRNA export from nucleus);GO:0005643(nuclear pore);GO:0000776(kinetochore);GO:0005829(cytosol);GO:0075733(intracellular transport of virus);GO:0043657(host cell);GO:0007062(sister chromatid cohesion);GO:0016032(viral process);GO:0016925(protein sumoylation);GO:0060964(regulation of gene silencing by miRNA);GO:0006110(regulation of glycolytic process);GO:0006409(tRNA export from nucleus);GO:0007077(mitotic nuclear envelope disassembly);GO:0019083(viral transcription);GO:1900034(regulation of cellular response to heat);GO:0005635(nuclear envelope);GO:0005487(nucleocytoplasmic transporter activity);GO:0031080(nuclear pore outer ring);GO:0031080(nuclear pore outer ring)","03013(RNA transport);03013(RNA transport)","K14303","NA","nucleoporin 160 [Source:HGNC Symbol;Acc:HGNC:18017]",{"v":2.48979095100764,"d":"2.49"},{"v":2.4241620399583,"d":"2.42"},{"v":1.02707282350254,"d":"1.03"},{"v":0.0385384780350984,"d":"0.04"},{"v":0.920563302912136,"d":"0.92"},1,"up","no"]
["MSTRG.13513","RPL21P75","ENST00000396599","NA","NA","NA","NA","ribosomal protein L21 pseudogene 75 [Source:HGNC Symbol;Acc:HGNC:36460]",{"v":207.463425,"d":"207.46"},{"v":201.996063,"d":"202.00"},{"v":1.02706667604705,"d":"1.03"},{"v":0.0385298428829582,"d":"0.04"},{"v":0.921114605027521,"d":"0.92"},1,"up","no"]
["ENSG00000176105","YES1","ENST00000314574;ENST00000584307;ENST00000581960","GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0005829(cytosol);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0004713(protein tyrosine kinase activity);GO:0018108(peptidyl-tyrosine phosphorylation);GO:0005886(plasma membrane);GO:0004715(non-membrane spanning protein tyrosine kinase activity);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005794(Golgi apparatus);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0005925(focal adhesion);GO:0005815(microtubule organizing center);GO:0038096(Fc-gamma receptor signaling pathway involved in phagocytosis);GO:0050900(leukocyte migration);GO:0045087(innate immune response);GO:0070062(extracellular exosome);GO:0030154(cell differentiation);GO:0044325(ion channel binding);GO:0019899(enzyme binding);GO:0042127(regulation of cell proliferation);GO:0006464(cellular protein modification process);GO:0048013(ephrin receptor signaling pathway);GO:0016477(cell migration);GO:0001784(phosphotyrosine residue binding);GO:0005102(receptor binding);GO:0031295(T cell costimulation);GO:0038083(peptidyl-tyrosine autophosphorylation);GO:0031234(extrinsic component of cytoplasmic side of plasma membrane);GO:0007169(transmembrane receptor protein tyrosine kinase signaling pathway);GO:0005154(epidermal growth factor receptor binding);GO:0015758(glucose transport);GO:0036120(cellular response to platelet-derived growth factor stimulus);GO:0043114(regulation of vascular permeability);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0046777(protein autophosphorylation);GO:0050731(positive regulation of peptidyl-tyrosine phosphorylation);GO:0071300(cellular response to retinoic acid);GO:0071560(cellular response to transforming growth factor beta stimulus);GO:0005884(actin filament);GO:0005884(actin filament)","04520(Adherens junction);04520(Adherens junction)","K05705","EC:2.7.10.2","YES proto-oncogene 1, Src family tyrosine kinase [Source:HGNC Symbol;Acc:HGNC:12841]",{"v":0.699336460980392,"d":"0.70"},{"v":0.678214716666667,"d":"0.68"},{"v":1.03114315244814,"d":"1.03"},{"v":0.0442446343457163,"d":"0.04"},{"v":0.922717419432711,"d":"0.92"},1,"up","no"]
["ENSG00000007923","DNAJC11","ENST00000377577;ENST00000426784;ENST00000485073;ENST00000465508;ENST00000294401","GO:0005739(mitochondrion);GO:0005515(protein binding);GO:0070062(extracellular exosome);GO:0005743(mitochondrial inner membrane);GO:0005743(mitochondrial inner membrane)","NA","NA","NA","DnaJ heat shock protein family (Hsp40) member C11 [Source:HGNC Symbol;Acc:HGNC:25570]",{"v":2.19220395553807,"d":"2.19"},{"v":2.3352988286445,"d":"2.34"},{"v":0.938725240919387,"d":"0.94"},{"v":-0.0912251431513954,"d":"-0.09"},{"v":0.923145250000598,"d":"0.92"},1,"down","no"]
["MSTRG.14391","LACTB2","ENST00000276590;ENST00000522447;ENST00000522558;ENST00000517601","GO:0003723(RNA binding);GO:0046872(metal ion binding);GO:0016787(hydrolase activity);GO:0008270(zinc ion binding);GO:0005739(mitochondrion);GO:0005515(protein binding);GO:0004519(endonuclease activity);GO:0004518(nuclease activity);GO:0005759(mitochondrial matrix);GO:0090502(RNA phosphodiester bond hydrolysis, endonucleolytic);GO:0004521(endoribonuclease activity);GO:0003727(single-stranded RNA binding);GO:0003727(single-stranded RNA binding)","NA","NA","NA","lactamase beta 2 [Source:HGNC Symbol;Acc:HGNC:18512]",{"v":2.46016333557742,"d":"2.46"},{"v":2.39076077421025,"d":"2.39"},{"v":1.02902948806749,"d":"1.03"},{"v":0.041284324971613,"d":"0.04"},{"v":0.923883388129278,"d":"0.92"},1,"up","no"]
["ENSG00000101400","SNTA1","ENST00000217381","GO:0060307(regulation of ventricular cardiac muscle cell membrane repolarization);GO:0002027(regulation of heart rate);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0003779(actin binding);GO:0005198(structural molecule activity);GO:0005886(plasma membrane);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0065009(regulation of molecular function);GO:0030054(cell junction);GO:0005516(calmodulin binding);GO:0005622(intracellular);GO:0042383(sarcolemma);GO:0017080(sodium channel regulator activity);GO:0044325(ion channel binding);GO:0006936(muscle contraction);GO:0051117(ATPase binding);GO:0016328(lateral plasma membrane);GO:0043234(protein complex);GO:0050998(nitric-oxide synthase binding);GO:1902083(negative regulation of peptidyl-cysteine S-nitrosylation);GO:0016013(syntrophin complex);GO:0086005(ventricular cardiac muscle cell action potential);GO:1902305(regulation of sodium ion transmembrane transport);GO:0030165(PDZ domain binding);GO:0031594(neuromuscular junction)","NA","NA","NA","syntrophin alpha 1 [Source:HGNC Symbol;Acc:HGNC:11167]",{"v":0.714831,"d":"0.71"},{"v":0.690493,"d":"0.69"},{"v":1.03524727984208,"d":"1.04"},{"v":0.0499754119678813,"d":"0.05"},{"v":0.925343460179248,"d":"0.93"},1,"up","no"]
["MSTRG.7452","NPC1","ENST00000269228;ENST00000590723;ENST00000586150;ENST00000591107;ENST00000540608;ENST00000591955;ENST00000586718;ENST00000590301;ENST00000587223;ENST00000591075;ENST00000591051;ENST00000593280;ENST00000588867;ENST00000587163","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005319(lipid transporter activity);GO:0006869(lipid transport);GO:0005765(lysosomal membrane);GO:0006629(lipid metabolic process);GO:0005783(endoplasmic reticulum);GO:0008202(steroid metabolic process);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0048471(perinuclear region of cytoplasm);GO:0006486(protein glycosylation);GO:0008203(cholesterol metabolic process);GO:0007165(signal transduction);GO:0005764(lysosome);GO:0005887(integral component of plasma membrane);GO:0005768(endosome);GO:0031902(late endosome membrane);GO:0070062(extracellular exosome);GO:0016032(viral process);GO:0006914(autophagy);GO:0004872(receptor activity);GO:0004888(transmembrane signaling receptor activity);GO:0005635(nuclear envelope);GO:0001618(virus receptor activity);GO:0015248(sterol transporter activity);GO:0015485(cholesterol binding);GO:0006897(endocytosis);GO:0007041(lysosomal transport);GO:0007628(adult walking behavior);GO:0008206(bile acid metabolic process);GO:0016242(negative regulation of macroautophagy);GO:0030301(cholesterol transport);GO:0031579(membrane raft organization);GO:0033344(cholesterol efflux);GO:0034383(low-density lipoprotein particle clearance);GO:0042493(response to drug);GO:0042632(cholesterol homeostasis);GO:0046686(response to cadmium ion);GO:0046718(viral entry into host cell);GO:0060548(negative regulation of cell death);GO:0071383(cellular response to steroid hormone stimulus);GO:0071404(cellular response to low-density lipoprotein particle stimulus);GO:0090150(establishment of protein localization to membrane);GO:2000189(positive regulation of cholesterol homeostasis);GO:0005794(Golgi apparatus);GO:0005886(plasma membrane);GO:0031982(vesicle);GO:0045121(membrane raft);GO:0045121(membrane raft)","04142(Lysosome);04979(Cholesterol metabolism);04979(Cholesterol metabolism)","K12385","NA","NPC intracellular cholesterol transporter 1 [Source:HGNC Symbol;Acc:HGNC:7897]",{"v":2.18101557285686,"d":"2.18"},{"v":2.32031828400317,"d":"2.32"},{"v":0.939963964380794,"d":"0.94"},{"v":-0.0893226459754462,"d":"-0.09"},{"v":0.925751658834357,"d":"0.93"},1,"down","no"]
["MSTRG.3393","CSAD","ENST00000379843;ENST00000498635;ENST00000267085;ENST00000483632;ENST00000424990;ENST00000491654;ENST00000490923;ENST00000454442;ENST00000379846;ENST00000461392;ENST00000424845;ENST00000379850;ENST00000472908;ENST00000475890;ENST00000453446;ENST00000444623;ENST00000485004","GO:0003824(catalytic activity);GO:0016829(lyase activity);GO:0016831(carboxy-lyase activity);GO:0030170(pyridoxal phosphate binding);GO:0019752(carboxylic acid metabolic process);GO:0042412(taurine biosynthetic process);GO:0004782(sulfinoalanine decarboxylase activity);GO:0004782(sulfinoalanine decarboxylase activity)","00430(Taurine and hypotaurine metabolism);00430(Taurine and hypotaurine metabolism)","K01594","EC:4.1.1.29","cysteine sulfinic acid decarboxylase [Source:HGNC Symbol;Acc:HGNC:18966]",{"v":2.20614438724374,"d":"2.21"},{"v":2.15901603348519,"d":"2.16"},{"v":1.02182862610912,"d":"1.02"},{"v":0.0311532579251979,"d":"0.03"},{"v":0.927500414110735,"d":"0.93"},1,"up","no"]
["MSTRG.2668","LRTOMT","ENST00000447974;ENST00000435085;ENST00000324866;ENST00000535883;ENST00000536917;ENST00000289488;ENST00000307198;ENST00000538413;ENST00000412777;ENST00000537483","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0008168(methyltransferase activity);GO:0016740(transferase activity);GO:0032259(methylation);GO:0007605(sensory perception of sound);GO:0008171(O-methyltransferase activity);GO:0005886(plasma membrane);GO:0016206(catechol O-methyltransferase activity);GO:0005575(cellular_component);GO:0006584(catecholamine metabolic process);GO:0042135(neurotransmitter catabolic process);GO:0102084(L-dopa O-methyltransferase activity);GO:0102938(-);GO:0042424(catecholamine catabolic process);GO:0060117(auditory receptor cell development);GO:0060117(auditory receptor cell development)","00140(Steroid hormone biosynthesis);00350(Tyrosine metabolism);04728(Dopaminergic synapse);04728(Dopaminergic synapse)","K00545","EC:2.1.1.6","leucine rich transmembrane and O-methyltransferase domain containing [Source:HGNC Symbol;Acc:HGNC:25033]",{"v":0.183234939615885,"d":"0.18"},{"v":0.180045282389323,"d":"0.18"},{"v":1.01771586116689,"d":"1.02"},{"v":0.0253348277159058,"d":"0.03"},{"v":0.928447951666915,"d":"0.93"},1,"up","no"]
["ENSG00000196312","MFSD14C","ENST00000637864;ENST00000637409;ENST00000602917;ENST00000375223;ENST00000637076;ENST00000637099;ENST00000637811;ENST00000506067","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005215(transporter activity);GO:0055085(transmembrane transport);GO:0006810(transport);GO:0006810(transport)","NA","NA","NA","major facilitator superfamily domain containing 14C [Source:HGNC Symbol;Acc:HGNC:23672]",{"v":0.671214124426605,"d":"0.67"},{"v":0.654482274369266,"d":"0.65"},{"v":1.0255650163688,"d":"1.03"},{"v":0.0364189553180689,"d":"0.04"},{"v":0.92940842908075,"d":"0.93"},1,"up","no"]
["ENSG00000101017","CD40","ENST00000372285;ENST00000489304;ENST00000466205;ENST00000620709;ENST00000461171","GO:0042531(positive regulation of tyrosine phosphorylation of STAT protein);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0001934(positive regulation of protein phosphorylation);GO:2000353(positive regulation of endothelial cell apoptotic process);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0004872(receptor activity);GO:0002376(immune system process);GO:0006955(immune response);GO:0050776(regulation of immune response);GO:0042113(B cell activation);GO:0009897(external side of plasma membrane);GO:0006954(inflammatory response);GO:0003823(antigen binding);GO:0019904(protein domain specific binding);GO:0002768(immune response-regulating cell surface receptor signaling pathway);GO:0006874(cellular calcium ion homeostasis);GO:0009617(response to bacterium);GO:0030890(positive regulation of B cell proliferation);GO:0031667(response to nutrient levels);GO:0032735(positive regulation of interleukin-12 production);GO:0033590(response to cobalamin);GO:0034341(response to interferon-gamma);GO:0036018(cellular response to erythropoietin);GO:0042832(defense response to protozoan);GO:0043491(protein kinase B signaling);GO:0048304(positive regulation of isotype switching to IgG isotypes);GO:0051023(regulation of immunoglobulin secretion);GO:0051607(defense response to virus);GO:0071222(cellular response to lipopolysaccharide);GO:0071347(cellular response to interleukin-1);GO:0071356(cellular response to tumor necrosis factor);GO:1901652(response to peptide);GO:0005615(extracellular space);GO:0005737(cytoplasm);GO:0009986(cell surface);GO:0035631(CD40 receptor complex);GO:0043025(neuronal cell body);GO:0043196(varicosity);GO:0043231(intracellular membrane-bounded organelle);GO:0070062(extracellular exosome);GO:0097190(apoptotic signaling pathway);GO:0033209(tumor necrosis factor-mediated signaling pathway);GO:0031625(ubiquitin protein ligase binding);GO:0005887(integral component of plasma membrane);GO:0043123(positive regulation of I-kappaB kinase/NF-kappaB signaling);GO:0004871(signal transducer activity);GO:0043547(positive regulation of GTPase activity);GO:0019899(enzyme binding);GO:0071260(cellular response to mechanical stimulus);GO:0005031(tumor necrosis factor-activated receptor activity);GO:0007275(multicellular organism development);GO:0032496(response to lipopolysaccharide);GO:0042127(regulation of cell proliferation);GO:0006461(protein complex assembly);GO:0051092(positive regulation of NF-kappaB transcription factor activity);GO:0043406(positive regulation of MAP kinase activity);GO:0030168(platelet activation);GO:0042100(B cell proliferation);GO:0090037(positive regulation of protein kinase C signaling);GO:0090037(positive regulation of protein kinase C signaling)","04064(NF-kappa B signaling pathway);04060(Cytokine-cytokine receptor interaction);04514(Cell adhesion molecules (CAMs));04620(Toll-like receptor signaling pathway);04672(Intestinal immune network for IgA production);05202(Transcriptional misregulation in cancers);05310(Asthma);05322(Systemic lupus erythematosus);05320(Autoimmune thyroid disease);05330(Allograft rejection);05340(Primary immunodeficiency);05416(Viral myocarditis);05166(HTLV-I infection);05169(Epstein-Barr virus infection);05144(Malaria);05145(Toxoplasmosis);05145(Toxoplasmosis)","K03160","NA","CD40 molecule [Source:HGNC Symbol;Acc:HGNC:11919]",{"v":1.7469302556391,"d":"1.75"},{"v":1.85473228848437,"d":"1.85"},{"v":0.941877308377824,"d":"0.94"},{"v":-0.0863889523773965,"d":"-0.09"},{"v":0.931067005606137,"d":"0.93"},1,"down","no"]
["MSTRG.8077","COX6B1","ENST00000246554;ENST00000392201;ENST00000590618;ENST00000592141","GO:0005739(mitochondrion);GO:1902600(hydrogen ion transmembrane transport);GO:0005758(mitochondrial intermembrane space);GO:0021762(substantia nigra development);GO:0004129(cytochrome-c oxidase activity);GO:0006123(mitochondrial electron transport, cytochrome c to oxygen);GO:0005743(mitochondrial inner membrane);GO:0005743(mitochondrial inner membrane)","00190(Oxidative phosphorylation);04260(Cardiac muscle contraction);05010(Alzheimer's disease);05012(Parkinson's disease);05016(Huntington's disease);04932(Non-alcoholic fatty liver disease (NAFLD));04932(Non-alcoholic fatty liver disease (NAFLD))","K02267","NA","cytochrome c oxidase subunit 6B1 [Source:HGNC Symbol;Acc:HGNC:2280]",{"v":56.8086842724359,"d":"56.81"},{"v":60.1882544871795,"d":"60.19"},{"v":0.943850004564205,"d":"0.94"},{"v":-0.0833704883355079,"d":"-0.08"},{"v":0.931235428105777,"d":"0.93"},1,"down","no"]
["ENSG00000162600","OMA1","ENST00000456980;ENST00000371226;ENST00000419242;ENST00000453710;ENST00000482274;ENST00000421528;ENST00000467509;ENST00000476933","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016787(hydrolase activity);GO:0008233(peptidase activity);GO:0006508(proteolysis);GO:0004222(metalloendopeptidase activity);GO:0008237(metallopeptidase activity);GO:0046872(metal ion binding);GO:0005743(mitochondrial inner membrane);GO:0006629(lipid metabolic process);GO:0005739(mitochondrion);GO:0031966(mitochondrial membrane);GO:0006006(glucose metabolic process);GO:0006515(misfolded or incompletely synthesized protein catabolic process);GO:0042981(regulation of apoptotic process);GO:0006950(response to stress);GO:0097009(energy homeostasis);GO:0002024(diet induced thermogenesis);GO:0010637(negative regulation of mitochondrial fusion);GO:0007005(mitochondrion organization);GO:0034982(mitochondrial protein processing);GO:0042407(cristae formation);GO:0042407(cristae formation)","NA","NA","NA","OMA1 zinc metallopeptidase [Source:HGNC Symbol;Acc:HGNC:29661]",{"v":3.32154452797203,"d":"3.32"},{"v":3.25847048466918,"d":"3.26"},{"v":1.01935694786852,"d":"1.02"},{"v":0.0276593279967092,"d":"0.03"},{"v":0.93173806513412,"d":"0.93"},1,"up","no"]
["ENSG00000148481","MINDY3","ENST00000477891;ENST00000476912;ENST00000436829;ENST00000418767;ENST00000277632;ENST00000378036","GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0016787(hydrolase activity);GO:0031965(nuclear membrane);GO:0005515(protein binding);GO:0008233(peptidase activity);GO:0008234(cysteine-type peptidase activity);GO:0006508(proteolysis);GO:0006915(apoptotic process);GO:0036459(thiol-dependent ubiquitinyl hydrolase activity);GO:1990380(Lys48-specific deubiquitinase activity);GO:0071108(protein K48-linked deubiquitination);GO:0016807(cysteine-type carboxypeptidase activity);GO:0016807(cysteine-type carboxypeptidase activity)","NA","NA","NA","MINDY lysine 48 deubiquitinase 3 [Source:HGNC Symbol;Acc:HGNC:23578]",{"v":0.769311832681974,"d":"0.77"},{"v":0.753858435759648,"d":"0.75"},{"v":1.02049907010294,"d":"1.02"},{"v":0.0292748677616215,"d":"0.03"},{"v":0.933695044738344,"d":"0.93"},1,"up","no"]
["MSTRG.3877","ANKLE2","ENST00000538766;ENST00000357997;ENST00000535036;ENST00000439231;ENST00000539605;ENST00000542374;ENST00000505031;ENST00000538591;ENST00000545623;ENST00000542282","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0051301(cell division);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005515(protein binding);GO:0007049(cell cycle);GO:0035307(positive regulation of protein dephosphorylation);GO:0051721(protein phosphatase 2A binding);GO:0007084(mitotic nuclear envelope reassembly);GO:0030176(integral component of endoplasmic reticulum membrane);GO:0050790(regulation of catalytic activity);GO:0043066(negative regulation of apoptotic process);GO:0019888(protein phosphatase regulator activity);GO:0007417(central nervous system development);GO:0042326(negative regulation of phosphorylation);GO:0042326(negative regulation of phosphorylation)","NA","NA","NA","ankyrin repeat and LEM domain containing 2 [Source:HGNC Symbol;Acc:HGNC:29101]",{"v":1.24020696614717,"d":"1.24"},{"v":1.31240415099618,"d":"1.31"},{"v":0.944988603705491,"d":"0.94"},{"v":-0.081631163941707,"d":"-0.08"},{"v":0.934464269718973,"d":"0.93"},1,"down","no"]
["ENSG00000166847","DCTN5","ENST00000300087;ENST00000568589;ENST00000563614;ENST00000566298;ENST00000563188;ENST00000563998;ENST00000568272","GO:0005737(cytoplasm);GO:0005654(nucleoplasm);GO:0031965(nuclear membrane);GO:0005694(chromosome);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0005813(centrosome);GO:0000775(chromosome, centromeric region);GO:0000776(kinetochore);GO:0000777(condensed chromosome kinetochore);GO:0005829(cytosol);GO:0019886(antigen processing and presentation of exogenous peptide antigen via MHC class II);GO:0006888(ER to Golgi vesicle-mediated transport);GO:0003281(ventricular septum development);GO:0035904(aorta development);GO:0060976(coronary vasculature development);GO:0060976(coronary vasculature development)","04962(Vasopressin-regulated water reabsorption);04962(Vasopressin-regulated water reabsorption)","K10427","NA","dynactin subunit 5 [Source:HGNC Symbol;Acc:HGNC:24594]",{"v":1.73555184678179,"d":"1.74"},{"v":1.70405319976452,"d":"1.70"},{"v":1.01848454439194,"d":"1.02"},{"v":0.0264240874237907,"d":"0.03"},{"v":0.935823954099185,"d":"0.94"},1,"up","no"]
["MSTRG.11899","ETFDH","ENST00000511912;ENST00000436096;ENST00000514148;ENST00000510353","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0046872(metal ion binding);GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0005743(mitochondrial inner membrane);GO:0005739(mitochondrion);GO:0031305(integral component of mitochondrial inner membrane);GO:0051536(iron-sulfur cluster binding);GO:0051539(4 iron, 4 sulfur cluster binding);GO:0050660(flavin adenine dinucleotide binding);GO:0031966(mitochondrial membrane);GO:0005759(mitochondrial matrix);GO:0006979(response to oxidative stress);GO:0009055(electron carrier activity);GO:0048039(ubiquinone binding);GO:0033539(fatty acid beta-oxidation using acyl-CoA dehydrogenase);GO:0022904(respiratory electron transport chain);GO:0048038(quinone binding);GO:0022900(electron transport chain);GO:0004174(electron-transferring-flavoprotein dehydrogenase activity);GO:0043783(oxidoreductase activity, oxidizing metal ions with flavin as acceptor);GO:0017133(mitochondrial electron transfer flavoprotein complex);GO:0017133(mitochondrial electron transfer flavoprotein complex)","NA","NA","NA","electron transfer flavoprotein dehydrogenase [Source:HGNC Symbol;Acc:HGNC:3483]",{"v":1.50011929423548,"d":"1.50"},{"v":1.4672193645671,"d":"1.47"},{"v":1.02242332023616,"d":"1.02"},{"v":0.031992647897315,"d":"0.03"},{"v":0.936735557635819,"d":"0.94"},1,"up","no"]
["ENSG00000172687","ZNF738","ENST00000597492;ENST00000311015;ENST00000594245;ENST00000380870","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0005622(intracellular);GO:0004842(ubiquitin-protein transferase activity);GO:0000209(protein polyubiquitination);GO:0000209(protein polyubiquitination)","NA","NA","NA","zinc finger protein 738 [Source:HGNC Symbol;Acc:HGNC:32469]",{"v":0.601630224327785,"d":"0.60"},{"v":0.584626537259923,"d":"0.58"},{"v":1.02908469934936,"d":"1.03"},{"v":0.0413617288815167,"d":"0.04"},{"v":0.937747435715755,"d":"0.94"},1,"up","no"]
["MSTRG.5974","GOT2","ENST00000245206;ENST00000568368;ENST00000564400;ENST00000496461;ENST00000492378;ENST00000494627","GO:0003723(RNA binding);GO:0006810(transport);GO:0016020(membrane);GO:0016740(transferase activity);GO:0003824(catalytic activity);GO:0009058(biosynthetic process);GO:0005739(mitochondrion);GO:0005886(plasma membrane);GO:0008483(transaminase activity);GO:0030170(pyridoxal phosphate binding);GO:0006869(lipid transport);GO:0005759(mitochondrial matrix);GO:0006520(cellular amino acid metabolic process);GO:0097052(L-kynurenine metabolic process);GO:0004069(L-aspartate:2-oxoglutarate aminotransferase activity);GO:0080130(L-phenylalanine:2-oxoglutarate aminotransferase activity);GO:0070062(extracellular exosome);GO:0006094(gluconeogenesis);GO:0019470(4-hydroxyproline catabolic process);GO:0006103(2-oxoglutarate metabolic process);GO:0008652(cellular amino acid biosynthetic process);GO:0045471(response to ethanol);GO:0005543(phospholipid binding);GO:0016212(kynurenine-oxoglutarate transaminase activity);GO:0016597(amino acid binding);GO:0019899(enzyme binding);GO:0031406(carboxylic acid binding);GO:0042803(protein homodimerization activity);GO:0047578(4-hydroxyglutamate transaminase activity);GO:0006107(oxaloacetate metabolic process);GO:0006531(aspartate metabolic process);GO:0006532(aspartate biosynthetic process);GO:0006533(aspartate catabolic process);GO:0006536(glutamate metabolic process);GO:0015908(fatty acid transport);GO:0019550(glutamate catabolic process to aspartate);GO:0019551(glutamate catabolic process to 2-oxoglutarate);GO:0043648(dicarboxylic acid metabolic process);GO:0046487(glyoxylate metabolic process);GO:0005743(mitochondrial inner membrane);GO:0009986(cell surface);GO:0043204(perikaryon);GO:0043209(myelin sheath);GO:0043234(protein complex);GO:0043234(protein complex)","00250(Alanine, aspartate and glutamate metabolism);00270(Cysteine and methionine metabolism);00220(Arginine biosynthesis);00330(Arginine and proline metabolism);00350(Tyrosine metabolism);00360(Phenylalanine metabolism);00400(Phenylalanine, tyrosine and tryptophan biosynthesis);04975(Fat digestion and absorption);04975(Fat digestion and absorption)","K14455","EC:2.6.1.1","glutamic-oxaloacetic transaminase 2 [Source:HGNC Symbol;Acc:HGNC:4433]",{"v":3.76042546468401,"d":"3.76"},{"v":3.69768903611259,"d":"3.70"},{"v":1.01696638845471,"d":"1.02"},{"v":0.0242719977686385,"d":"0.02"},{"v":0.938287243162023,"d":"0.94"},1,"up","no"]
["MSTRG.15189","RBBP7","ENST00000380087;ENST00000425696;ENST00000486166;ENST00000380084;ENST00000481586;ENST00000416035;ENST00000330735;ENST00000493145;ENST00000468092;ENST00000465244;ENST00000404022","GO:0005634(nucleus);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0016569(covalent chromatin modification);GO:0016575(histone deacetylation);GO:0005515(protein binding);GO:0006260(DNA replication);GO:0043687(post-translational protein modification);GO:0035098(ESC/E(Z) complex);GO:0034080(CENP-A containing nucleosome assembly);GO:0007275(multicellular organism development);GO:0030308(negative regulation of cell growth);GO:1901796(regulation of signal transduction by p53 class mediator);GO:0004407(histone deacetylase activity);GO:0008283(cell proliferation);GO:0045814(negative regulation of gene expression, epigenetic);GO:0016581(NuRD complex);GO:0070370(cellular heat acclimation);GO:0003723(RNA binding);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0045892(negative regulation of transcription, DNA-templated);GO:0048545(response to steroid hormone);GO:0048545(response to steroid hormone)","NA","NA","NA","RB binding protein 7, chromatin remodeling factor [Source:HGNC Symbol;Acc:HGNC:9890]",{"v":3.12479840232684,"d":"3.12"},{"v":3.29232405438312,"d":"3.29"},{"v":0.94911629314458,"d":"0.95"},{"v":-0.0753432265409047,"d":"-0.08"},{"v":0.939568240954919,"d":"0.94"},1,"down","no"]
["ENSG00000215302","AC127502.1","ENST00000564702;ENST00000568690;ENST00000399971","NA","NA","NA","NA",null,{"v":0.588721802230802,"d":"0.59"},{"v":0.569837533676534,"d":"0.57"},{"v":1.03313974148461,"d":"1.03"},{"v":0.0470354049404686,"d":"0.05"},{"v":0.9405242232691,"d":"0.94"},1,"up","no"]
["ENSG00000117586","TNFSF4","ENST00000367718;ENST00000488053;ENST00000281834","GO:0005615(extracellular space);GO:0043433(negative regulation of sequence-specific DNA binding transcription factor activity);GO:0045590(negative regulation of regulatory T cell differentiation);GO:0050729(positive regulation of inflammatory response);GO:0032755(positive regulation of interleukin-6 production);GO:0071222(cellular response to lipopolysaccharide);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0006955(immune response);GO:0005125(cytokine activity);GO:0005164(tumor necrosis factor receptor binding);GO:0005886(plasma membrane);GO:0033209(tumor necrosis factor-mediated signaling pathway);GO:0005887(integral component of plasma membrane);GO:0009986(cell surface);GO:0007165(signal transduction);GO:0032689(negative regulation of interferon-gamma production);GO:0032700(negative regulation of interleukin-17 production);GO:0032729(positive regulation of interferon-gamma production);GO:0032733(positive regulation of interleukin-10 production);GO:0032735(positive regulation of interleukin-12 production);GO:0005102(receptor binding);GO:0045892(negative regulation of transcription, DNA-templated);GO:0032813(tumor necrosis factor receptor superfamily binding);GO:0071380(cellular response to prostaglandin E stimulus);GO:0008284(positive regulation of cell proliferation);GO:0050727(regulation of inflammatory response);GO:0002526(acute inflammatory response);GO:0009615(response to virus);GO:0002726(positive regulation of T cell cytokine production);GO:0051024(positive regulation of immunoglobulin secretion);GO:0050871(positive regulation of B cell activation);GO:0032736(positive regulation of interleukin-13 production);GO:0032753(positive regulation of interleukin-4 production);GO:0045630(positive regulation of T-helper 2 cell differentiation);GO:0002215(defense response to nematode);GO:0002819(regulation of adaptive immune response);GO:0002830(positive regulation of type 2 immune response);GO:0002891(positive regulation of immunoglobulin mediated immune response);GO:0035709(memory T cell activation);GO:0035712(T-helper 2 cell activation);GO:0035713(response to nitrogen dioxide);GO:0042102(positive regulation of T cell proliferation);GO:0043372(positive regulation of CD4-positive, alpha-beta T cell differentiation);GO:0043382(positive regulation of memory T cell differentiation);GO:0045626(negative regulation of T-helper 1 cell differentiation);GO:0046641(positive regulation of alpha-beta T cell proliferation);GO:0071954(chemokine (C-C motif) ligand 11 production);GO:1900281(positive regulation of CD4-positive, alpha-beta T cell costimulation);GO:2000572(positive regulation of interleukin-4-dependent isotype switching to IgE isotypes);GO:0001816(cytokine production);GO:0006954(inflammatory response);GO:0008203(cholesterol metabolic process);GO:0032743(positive regulation of interleukin-2 production);GO:0035714(cellular response to nitrogen dioxide);GO:0035783(CD4-positive, alpha-beta T cell costimulation);GO:0042098(T cell proliferation);GO:0042104(positive regulation of activated T cell proliferation);GO:0050710(negative regulation of cytokine secretion);GO:2000525(positive regulation of T cell costimulation);GO:2000568(positive regulation of memory T cell activation);GO:2000570(positive regulation of T-helper 2 cell activation);GO:2000570(positive regulation of T-helper 2 cell activation)","04060(Cytokine-cytokine receptor interaction);04060(Cytokine-cytokine receptor interaction)","K05469","NA","TNF superfamily member 4 [Source:HGNC Symbol;Acc:HGNC:11934]",{"v":1.14734785235921,"d":"1.15"},{"v":1.2128943630137,"d":"1.21"},{"v":0.945958598989919,"d":"0.95"},{"v":-0.0801510512158933,"d":"-0.08"},{"v":0.941311936777993,"d":"0.94"},1,"down","no"]
["MSTRG.1450","RAB4A","ENST00000473894;ENST00000618010;ENST00000366690;ENST00000489342;ENST00000481981","GO:0006810(transport);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0015031(protein transport);GO:0005525(GTP binding);GO:0000166(nucleotide binding);GO:0003924(GTPase activity);GO:0005515(protein binding);GO:0048471(perinuclear region of cytoplasm);GO:0001671(ATPase activator activity);GO:0008565(protein transporter activity);GO:0019905(syntaxin binding);GO:0035255(ionotropic glutamate receptor binding);GO:0051117(ATPase binding);GO:0030100(regulation of endocytosis);GO:0032482(Rab protein signal transduction);GO:0032781(positive regulation of ATPase activity);GO:0005768(endosome);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0032593(insulin-responsive compartment);GO:0043231(intracellular membrane-bounded organelle);GO:0055037(recycling endosome);GO:0098837(postsynaptic recycling endosome);GO:0070062(extracellular exosome);GO:0061024(membrane organization);GO:0019003(GDP binding);GO:0031982(vesicle);GO:0006661(phosphatidylinositol biosynthetic process);GO:0030659(cytoplasmic vesicle membrane);GO:0031901(early endosome membrane);GO:0019882(antigen processing and presentation);GO:0019882(antigen processing and presentation)","04144(Endocytosis);04144(Endocytosis)","K07879","NA","RAB4A, member RAS oncogene family [Source:HGNC Symbol;Acc:HGNC:9781]",{"v":4.20208887492447,"d":"4.20"},{"v":4.13889366706949,"d":"4.14"},{"v":1.01526862319701,"d":"1.02"},{"v":0.0218614910372241,"d":"0.02"},{"v":0.943039768743923,"d":"0.94"},1,"up","no"]
["MSTRG.245","STPG1","ENST00000483261;ENST00000438866;ENST00000497384;ENST00000483528;ENST00000498488;ENST00000435187;ENST00000475760;ENST00000468303;ENST00000003583;ENST00000374409","GO:0005739(mitochondrion);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0006915(apoptotic process);GO:0003674(molecular_function);GO:0005622(intracellular);GO:0043065(positive regulation of apoptotic process);GO:1902110(positive regulation of mitochondrial membrane permeability involved in apoptotic process);GO:0090073(positive regulation of protein homodimerization activity);GO:0090073(positive regulation of protein homodimerization activity)","NA","NA","NA","sperm tail PG-rich repeat containing 1 [Source:HGNC Symbol;Acc:HGNC:28070]",{"v":0.214561119257432,"d":"0.21"},{"v":0.210313044178122,"d":"0.21"},{"v":1.02019881884127,"d":"1.02"},{"v":0.0288503355349782,"d":"0.03"},{"v":0.94354226208232,"d":"0.94"},1,"up","no"]
["ENSG00000215769","ARHGAP27P1-BPTFP1-KPNA2P3","ENST00000578492;ENST00000579125","NA","NA","NA","NA","ARHGAP27P1-BPTFP1-KPNA2P3 readthrough, transcribed pseudogene [Source:HGNC Symbol;Acc:HGNC:52873]",{"v":2.54516735088874,"d":"2.55"},{"v":2.50679884792627,"d":"2.51"},{"v":1.01530577652619,"d":"1.02"},{"v":0.0219142848907978,"d":"0.02"},{"v":0.944934156311935,"d":"0.94"},1,"up","no"]
["MSTRG.11962","MED10","ENST00000255764;ENST00000503112;ENST00000504058","GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0001104(RNA polymerase II transcription cofactor activity);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0016592(mediator complex);GO:0005515(protein binding);GO:0006367(transcription initiation from RNA polymerase II promoter);GO:0070847(core mediator complex);GO:0061630(ubiquitin protein ligase activity);GO:0016567(protein ubiquitination);GO:0019827(stem cell population maintenance);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0000151(ubiquitin ligase complex);GO:0000151(ubiquitin ligase complex)","NA","NA","NA","mediator complex subunit 10 [Source:HGNC Symbol;Acc:HGNC:28760]",{"v":4.02927236702128,"d":"4.03"},{"v":4.23739096648936,"d":"4.24"},{"v":0.950885202447934,"d":"0.95"},{"v":-0.0726569155848536,"d":"-0.07"},{"v":0.945613566270368,"d":"0.95"},1,"down","no"]
["MSTRG.6006","TPPP3","ENST00000393957;ENST00000561537;ENST00000562206;ENST00000564104","GO:0005737(cytoplasm);GO:0005856(cytoskeleton);GO:0048471(perinuclear region of cytoplasm);GO:0015631(tubulin binding);GO:0001578(microtubule bundle formation);GO:0005874(microtubule);GO:0046785(microtubule polymerization);GO:0070062(extracellular exosome);GO:0097427(microtubule bundle);GO:0097427(microtubule bundle)","NA","NA","NA","tubulin polymerization promoting protein family member 3 [Source:HGNC Symbol;Acc:HGNC:24162]",{"v":1.77059119136746,"d":"1.77"},{"v":1.86317806531704,"d":"1.86"},{"v":0.950307018060657,"d":"0.95"},{"v":-0.0735344110479227,"d":"-0.07"},{"v":0.947106550142652,"d":"0.95"},1,"down","no"]
["MSTRG.4486","MPP5","ENST00000261681;ENST00000555925;ENST00000556345;ENST00000554208","GO:0016020(membrane);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0030054(cell junction);GO:0070830(bicellular tight junction assembly);GO:0005923(bicellular tight junction);GO:0090162(establishment of epithelial cell polarity);GO:0005737(cytoplasm);GO:0070062(extracellular exosome);GO:0019904(protein domain specific binding);GO:0012505(endomembrane system);GO:0002011(morphogenesis of an epithelial sheet);GO:0007009(plasma membrane organization);GO:0032287(peripheral nervous system myelin maintenance);GO:0032288(myelin assembly);GO:0035750(protein localization to myelin sheath abaxonal region);GO:0090002(establishment of protein localization to plasma membrane);GO:0035749(myelin sheath adaxonal region);GO:0043219(lateral loop);GO:0043220(Schmidt-Lanterman incisure);GO:0043234(protein complex);GO:0043234(protein complex)","04390(Hippo signaling pathway);04530(Tight junction);05165(Human papillomavirus infection);05165(Human papillomavirus infection)","K06091","NA","membrane palmitoylated protein 5 [Source:HGNC Symbol;Acc:HGNC:18669]",{"v":0.493315209424683,"d":"0.49"},{"v":0.521013574288002,"d":"0.52"},{"v":0.946837537004347,"d":"0.95"},{"v":-0.0788111925996462,"d":"-0.08"},{"v":0.947928360094721,"d":"0.95"},1,"down","no"]
["ENSG00000100427","MLC1","ENST00000311597;ENST00000395876;ENST00000483836","GO:0006810(transport);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005783(endoplasmic reticulum);GO:0006811(ion transport);GO:0005886(plasma membrane);GO:0005901(caveola);GO:0048471(perinuclear region of cytoplasm);GO:0031410(cytoplasmic vesicle);GO:0045121(membrane raft);GO:0005764(lysosome);GO:0016192(vesicle-mediated transport);GO:0005515(protein binding);GO:0005768(endosome);GO:0016323(basolateral plasma membrane);GO:0005769(early endosome);GO:0055037(recycling endosome);GO:0051259(protein oligomerization);GO:0008565(protein transporter activity);GO:0032403(protein complex binding);GO:0005215(transporter activity);GO:0071397(cellular response to cholesterol);GO:0072584(caveolin-mediated endocytosis);GO:0032388(positive regulation of intracellular transport);GO:0047484(regulation of response to osmotic stress);GO:0015031(protein transport);GO:0005911(cell-cell junction);GO:0016324(apical plasma membrane);GO:0016324(apical plasma membrane)","NA","NA","NA","megalencephalic leukoencephalopathy with subcortical cysts 1 [Source:HGNC Symbol;Acc:HGNC:17082]",{"v":2.77962143542006,"d":"2.78"},{"v":2.74573100232721,"d":"2.75"},{"v":1.01234295459538,"d":"1.01"},{"v":0.0176981191583494,"d":"0.02"},{"v":0.948245923662561,"d":"0.95"},1,"up","no"]
["MSTRG.11388","PSMD2","ENST00000310118;ENST00000492191;ENST00000459910;ENST00000491494;ENST00000488085;ENST00000487475;ENST00000460628;ENST00000445558;ENST00000485937;ENST00000476461;ENST00000491149;ENST00000473991;ENST00000496925;ENST00000466987;ENST00000433010;ENST00000435761","GO:0016020(membrane);GO:0005515(protein binding);GO:0000502(proteasome complex);GO:0038095(Fc-epsilon receptor signaling pathway);GO:0005576(extracellular region);GO:0005634(nucleus);GO:0030234(enzyme regulator activity);GO:0042176(regulation of protein catabolic process);GO:0004175(endopeptidase activity);GO:0043161(proteasome-mediated ubiquitin-dependent protein catabolic process);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0000165(MAPK cascade);GO:0000209(protein polyubiquitination);GO:0002223(stimulatory C-type lectin receptor signaling pathway);GO:0002479(antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent);GO:0006521(regulation of cellular amino acid metabolic process);GO:0010972(negative regulation of G2/M transition of mitotic cell cycle);GO:0016579(protein deubiquitination);GO:0031145(anaphase-promoting complex-dependent catabolic process);GO:0031146(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process);GO:0033209(tumor necrosis factor-mediated signaling pathway);GO:0038061(NIK/NF-kappaB signaling);GO:0043488(regulation of mRNA stability);GO:0043687(post-translational protein modification);GO:0050852(T cell receptor signaling pathway);GO:0051437(positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition);GO:0055085(transmembrane transport);GO:0060071(Wnt signaling pathway, planar cell polarity pathway);GO:0061418(regulation of transcription from RNA polymerase II promoter in response to hypoxia);GO:0090090(negative regulation of canonical Wnt signaling pathway);GO:0090263(positive regulation of canonical Wnt signaling pathway);GO:1902036(regulation of hematopoietic stem cell differentiation);GO:0043312(neutrophil degranulation);GO:0051436(negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle);GO:0022624(proteasome accessory complex);GO:0034774(secretory granule lumen);GO:1904813(ficolin-1-rich granule lumen);GO:0005838(proteasome regulatory particle);GO:0008540(proteasome regulatory particle, base subcomplex);GO:0034515(proteasome storage granule);GO:0050790(regulation of catalytic activity);GO:0050790(regulation of catalytic activity)","03050(Proteasome);05169(Epstein-Barr virus infection);05169(Epstein-Barr virus infection)","K03028","NA","proteasome 26S subunit, non-ATPase 2 [Source:HGNC Symbol;Acc:HGNC:9559]",{"v":10.5757697828718,"d":"10.58"},{"v":11.0833370865579,"d":"11.08"},{"v":0.95420446931081,"d":"0.95"},{"v":-0.0676296512423174,"d":"-0.07"},{"v":0.949724119435444,"d":"0.95"},1,"down","no"]
["MSTRG.21","AL732372.2;AL627309.2","ENST00000642074;MSTRG.21.1;ENST00000601486;ENST00000641579;ENST00000616311;ENST00000493797;ENST00000445840;ENST00000419160;ENST00000455464;ENST00000601814;ENST00000641049;ENST00000440038;ENST00000642124;ENST00000608420;ENST00000431812;ENST00000641063;ENST00000455207;ENST00000641303;ENST00000616947","NA","NA","NA","NA",null,{"v":3.91993132766529,"d":"3.92"},{"v":4.11198502785547,"d":"4.11"},{"v":0.953294163551383,"d":"0.95"},{"v":-0.0690066312116772,"d":"-0.07"},{"v":0.950379376111216,"d":"0.95"},1,"down","no"]
["MSTRG.12446","AC021078.1;CSNK1A1","ENST00000499521;ENST00000261798;ENST00000377843;ENST00000503350;ENST00000523203;ENST00000515435;ENST00000504676;ENST00000515768;ENST00000606299;ENST00000515748;ENST00000606719","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016607(nuclear speck);GO:0016020(membrane);GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0005829(cytosol);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0051301(cell division);GO:0005694(chromosome);GO:0005856(cytoskeleton);GO:0042995(cell projection);GO:0005515(protein binding);GO:0007049(cell cycle);GO:0016055(Wnt signaling pathway);GO:0005813(centrosome);GO:0005815(microtubule organizing center);GO:0000775(chromosome, centromeric region);GO:0000776(kinetochore);GO:0000777(condensed chromosome kinetochore);GO:0005929(cilium);GO:0036064(ciliary basal body);GO:0043161(proteasome-mediated ubiquitin-dependent protein catabolic process);GO:0008360(regulation of cell shape);GO:0007165(signal transduction);GO:0007166(cell surface receptor signaling pathway);GO:0006909(phagocytosis);GO:1904886(beta-catenin destruction complex disassembly);GO:0045104(intermediate filament cytoskeleton organization);GO:0007030(Golgi organization);GO:0090090(negative regulation of canonical Wnt signaling pathway);GO:1904885(beta-catenin destruction complex assembly);GO:0032436(positive regulation of proteasomal ubiquitin-dependent protein catabolic process);GO:0018105(peptidyl-serine phosphorylation);GO:0005847(mRNA cleavage and polyadenylation specificity factor complex);GO:0045095(keratin filament);GO:1904424(regulation of GTP binding);GO:0030877(beta-catenin destruction complex);GO:0000902(cell morphogenesis);GO:0030529(intracellular ribonucleoprotein complex);GO:0030529(intracellular ribonucleoprotein complex)","04310(Wnt signaling pathway);04340(Hedgehog signaling pathway);05225(Hepatocellular carcinoma);05226(Gastric cancer);05224(Breast cancer);05165(Human papillomavirus infection);05165(Human papillomavirus infection)","K08957","EC:2.7.11.1","casein kinase 1 alpha 1 [Source:HGNC Symbol;Acc:HGNC:2451]",{"v":2.93634266800357,"d":"2.94"},{"v":3.07542774138443,"d":"3.08"},{"v":0.954775372703685,"d":"0.95"},{"v":-0.0667667405921846,"d":"-0.07"},{"v":0.951605687766097,"d":"0.95"},1,"down","no"]
["MSTRG.1076","TMEM79","ENST00000295694;ENST00000495881","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005794(Golgi apparatus);GO:0005765(lysosomal membrane);GO:0005515(protein binding);GO:0005764(lysosome);GO:0042802(identical protein binding);GO:0070268(cornification);GO:0032588(trans-Golgi network membrane);GO:0061436(establishment of skin barrier);GO:0002070(epithelial cell maturation);GO:0045055(regulated exocytosis);GO:0045684(positive regulation of epidermis development);GO:0031069(hair follicle morphogenesis);GO:0042335(cuticle development);GO:0005737(cytoplasm);GO:0005737(cytoplasm)","NA","NA","NA","transmembrane protein 79 [Source:HGNC Symbol;Acc:HGNC:28196]",{"v":0.69429870101076,"d":"0.69"},{"v":0.730274102054125,"d":"0.73"},{"v":0.950737126043258,"d":"0.95"},{"v":-0.0728815964711985,"d":"-0.07"},{"v":0.952897587597223,"d":"0.95"},1,"down","no"]
["MSTRG.7621","CSNK1G2","ENST00000255641;ENST00000615564;ENST00000589350;ENST00000585959;ENST00000590106;ENST00000591002;ENST00000589385;ENST00000585957;ENST00000591752","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0005515(protein binding);GO:0016055(Wnt signaling pathway);GO:0005634(nucleus);GO:0005829(cytosol);GO:0008360(regulation of cell shape);GO:0007165(signal transduction);GO:0030148(sphingolipid biosynthetic process);GO:0006897(endocytosis);GO:0018105(peptidyl-serine phosphorylation);GO:0000287(magnesium ion binding);GO:0042277(peptide binding);GO:0051219(phosphoprotein binding);GO:0046777(protein autophosphorylation);GO:0046777(protein autophosphorylation)","04340(Hedgehog signaling pathway);04340(Hedgehog signaling pathway)","K08958","EC:2.7.11.1","casein kinase 1 gamma 2 [Source:HGNC Symbol;Acc:HGNC:2455]",{"v":15.2990223233438,"d":"15.30"},{"v":16.0036221198738,"d":"16.00"},{"v":0.955972479776625,"d":"0.96"},{"v":-0.0649590079169712,"d":"-0.06"},{"v":0.953412765213959,"d":"0.95"},1,"down","no"]
["MSTRG.14615","PLEC","ENST00000527096;ENST00000527303;ENST00000345136;ENST00000354958;ENST00000357649;ENST00000398774;ENST00000436759;ENST00000532346;ENST00000354589;ENST00000322810;ENST00000528025","GO:0003723(RNA binding);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0003779(actin binding);GO:0005925(focal adhesion);GO:0045111(intermediate filament cytoskeleton);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0008092(cytoskeletal protein binding);GO:0030054(cell junction);GO:0045296(cadherin binding);GO:0070062(extracellular exosome);GO:0042383(sarcolemma);GO:0031012(extracellular matrix);GO:0005886(plasma membrane);GO:0008307(structural constituent of muscle);GO:0030506(ankyrin binding);GO:0031581(hemidesmosome assembly);GO:0030056(hemidesmosome);GO:0043034(costamere);GO:0016528(sarcoplasm);GO:0005903(brush border);GO:0043292(contractile fiber);GO:0043292(contractile fiber)","NA","NA","NA","plectin [Source:HGNC Symbol;Acc:HGNC:9069]",{"v":8.00207000200106,"d":"8.00"},{"v":7.93874487611088,"d":"7.94"},{"v":1.00797671758929,"d":"1.01"},{"v":0.011462315617203,"d":"0.01"},{"v":0.95398322009892,"d":"0.95"},1,"up","no"]
["MSTRG.78","AL031282.1","ENST00000417099;ENST00000424604;ENST00000577672;ENST00000418950","NA","NA","NA","NA",null,{"v":1.15667413265676,"d":"1.16"},{"v":1.21602068503081,"d":"1.22"},{"v":0.95119609961853,"d":"0.95"},{"v":-0.0721852955655057,"d":"-0.07"},{"v":0.955488031212276,"d":"0.96"},1,"down","no"]
["MSTRG.6019","AC009061.2","ENST00000635000;ENST00000602476;ENST00000602592;ENST00000602596","NA","NA","NA","NA",null,{"v":0.498399344404332,"d":"0.50"},{"v":0.523642754873646,"d":"0.52"},{"v":0.951792686455854,"d":"0.95"},{"v":-0.0712807259682887,"d":"-0.07"},{"v":0.957010191628654,"d":"0.96"},1,"down","no"]
["ENSG00000074266","EED","ENST00000263360;ENST00000525244;ENST00000327320;ENST00000351625;ENST00000528180;ENST00000528250;ENST00000534564;ENST00000527888;ENST00000524673","GO:0005634(nucleus);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0016569(covalent chromatin modification);GO:0005694(chromosome);GO:0005515(protein binding);GO:0042802(identical protein binding);GO:0035098(ESC/E(Z) complex);GO:0045892(negative regulation of transcription, DNA-templated);GO:0045814(negative regulation of gene expression, epigenetic);GO:0042054(histone methyltransferase activity);GO:0046976(histone methyltransferase activity (H3-K27 specific));GO:0070734(histone H3-K27 methylation);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:0003682(chromatin binding);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0006349(regulation of gene expression by genetic imprinting);GO:0016571(histone methylation);GO:0021510(spinal cord development);GO:0061087(positive regulation of histone H3-K27 methylation);GO:1990830(cellular response to leukemia inhibitory factor);GO:2000011(regulation of adaxial/abaxial pattern formation);GO:0001739(sex chromatin);GO:0045120(pronucleus);GO:0045120(pronucleus)","NA","NA","NA","embryonic ectoderm development [Source:HGNC Symbol;Acc:HGNC:3188]",{"v":0.493650629561003,"d":"0.49"},{"v":0.485216769099202,"d":"0.49"},{"v":1.01738163435171,"d":"1.02"},{"v":0.0248609561945837,"d":"0.02"},{"v":0.95762821675659,"d":"0.96"},1,"up","no"]
["MSTRG.8842","AUP1","ENST00000425118;ENST00000377526;ENST00000466894;MSTRG.8842.2;ENST00000472800;ENST00000486234;ENST00000464887;ENST00000462297;ENST00000463900","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0050790(regulation of catalytic activity);GO:0005515(protein binding);GO:0030970(retrograde protein transport, ER to cytosol);GO:0070062(extracellular exosome);GO:0030176(integral component of endoplasmic reticulum membrane);GO:0043130(ubiquitin binding);GO:0030433(ubiquitin-dependent ERAD pathway);GO:0097027(ubiquitin-protein transferase activator activity);GO:0000839(Hrd1p ubiquitin ligase ERAD-L complex);GO:0000839(Hrd1p ubiquitin ligase ERAD-L complex)","NA","NA","NA","ancient ubiquitous protein 1 [Source:HGNC Symbol;Acc:HGNC:891]",{"v":22.6257037758204,"d":"22.63"},{"v":22.5102729879102,"d":"22.51"},{"v":1.00512791595074,"d":"1.01"},{"v":7.3791152991874E-3,"d":"0.01"},{"v":0.958865112414481,"d":"0.96"},1,"up","no"]
["MSTRG.4220","TRAV38-2DV8","ENST00000390465","GO:0002377(immunoglobulin production);GO:0006955(immune response);GO:0005615(extracellular space)","NA","NA","NA","T-cell receptor alpha variable 38-2/delta variable 8 [Source:HGNC Symbol;Acc:HGNC:12138]",{"v":2.518483,"d":"2.52"},{"v":2.494874,"d":"2.49"},{"v":1.00946300294123,"d":"1.01"},{"v":0.0135880365224679,"d":"0.01"},{"v":0.959678963209091,"d":"0.96"},1,"up","no"]
["ENSG00000167114","SLC27A4","ENST00000372870;ENST00000300456","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0000166(nucleotide binding);GO:0003824(catalytic activity);GO:0006629(lipid metabolic process);GO:0008152(metabolic process);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0006631(fatty acid metabolic process);GO:0016874(ligase activity);GO:0006869(lipid transport);GO:0004467(long-chain fatty acid-CoA ligase activity);GO:0031957(very long-chain fatty acid-CoA ligase activity);GO:0015908(fatty acid transport);GO:0005886(plasma membrane);GO:0001676(long-chain fatty acid metabolic process);GO:0044539(long-chain fatty acid import);GO:0015909(long-chain fatty acid transport);GO:0015245(fatty acid transporter activity);GO:0000038(very long-chain fatty acid metabolic process);GO:0001579(medium-chain fatty acid transport);GO:0007584(response to nutrient);GO:0042760(very long-chain fatty acid catabolic process);GO:0043588(skin development);GO:0005902(microvillus);GO:0031526(brush border membrane);GO:0031526(brush border membrane)","03320(PPAR signaling pathway);04975(Fat digestion and absorption);04931(Insulin resistance);04931(Insulin resistance)","K08745","EC:6.2.1.-","solute carrier family 27 member 4 [Source:HGNC Symbol;Acc:HGNC:10998]",{"v":2.1831110829582,"d":"2.18"},{"v":2.27786801028939,"d":"2.28"},{"v":0.958401045669388,"d":"0.96"},{"v":-0.0612986126984582,"d":"-0.06"},{"v":0.960452887433638,"d":"0.96"},1,"down","no"]
["ENSG00000186666","BCDIN3D","ENST00000333924;ENST00000550861","GO:0005737(cytoplasm);GO:0005634(nucleus);GO:0005829(cytosol);GO:0008168(methyltransferase activity);GO:0016740(transferase activity);GO:0032259(methylation);GO:0005515(protein binding);GO:0010586(miRNA metabolic process);GO:0008171(O-methyltransferase activity);GO:0008173(RNA methyltransferase activity);GO:0001510(RNA methylation);GO:2000632(negative regulation of pre-miRNA processing);GO:2000632(negative regulation of pre-miRNA processing)","NA","NA","NA","BCDIN3 domain containing RNA methyltransferase [Source:HGNC Symbol;Acc:HGNC:27050]",{"v":0.884284228970707,"d":"0.88"},{"v":0.876020276001075,"d":"0.88"},{"v":1.00943351791737,"d":"1.01"},{"v":0.0135458967720908,"d":"0.01"},{"v":0.961773060632388,"d":"0.96"},1,"up","no"]
["ENSG00000267534","S1PR2","ENST00000590320","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0004930(G-protein coupled receptor activity);GO:0007186(G-protein coupled receptor signaling pathway);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0004871(signal transducer activity);GO:0007165(signal transduction);GO:0038036(sphingosine-1-phosphate receptor activity);GO:0003376(sphingosine-1-phosphate signaling pathway);GO:0010800(positive regulation of peptidyl-threonine phosphorylation);GO:0090394(negative regulation of excitatory postsynaptic potential);GO:0005178(integrin binding);GO:0001664(G-protein coupled receptor binding);GO:1903142(positive regulation of establishment of endothelial barrier);GO:0031532(actin cytoskeleton reorganization);GO:0008289(lipid binding);GO:0008284(positive regulation of cell proliferation);GO:0000187(activation of MAPK activity);GO:0046847(filopodium assembly)","04071(Sphingolipid signaling pathway);04080(Neuroactive ligand-receptor interaction)","K04292","NA","sphingosine-1-phosphate receptor 2 [Source:HGNC Symbol;Acc:HGNC:3169]",{"v":0.90793,"d":"0.91"},{"v":0.949117,"d":"0.95"},{"v":0.956604928580986,"d":"0.96"},{"v":-0.0640048705493131,"d":"-0.06"},{"v":0.962317976895328,"d":"0.96"},1,"down","no"]
["ENSG00000260267","AC026471.1","ENST00000564629","NA","NA","NA","NA",null,{"v":0.742266,"d":"0.74"},{"v":0.773716,"d":"0.77"},{"v":0.959352010298352,"d":"0.96"},{"v":-0.0598678215312132,"d":"-0.06"},{"v":0.9637641042117,"d":"0.96"},1,"down","no"]
["MSTRG.9967","APP","ENST00000358918;ENST00000346798;MSTRG.9967.1;ENST00000357903;ENST00000348990;ENST00000464867;ENST00000491395;ENST00000474136;ENST00000548570;ENST00000466453;ENST00000463070;ENST00000359726","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0046872(metal ion binding);GO:0003677(DNA binding);GO:0007155(cell adhesion);GO:0005794(Golgi apparatus);GO:0004867(serine-type endopeptidase inhibitor activity);GO:0010951(negative regulation of endopeptidase activity);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0007399(nervous system development);GO:0006915(apoptotic process);GO:0048471(perinuclear region of cytoplasm);GO:0005615(extracellular space);GO:0007219(Notch signaling pathway);GO:0005790(smooth endoplasmic reticulum);GO:0005905(clathrin-coated pit);GO:0008201(heparin binding);GO:0005576(extracellular region);GO:0030414(peptidase inhibitor activity);GO:0010466(negative regulation of peptidase activity);GO:0042802(identical protein binding);GO:0046914(transition metal ion binding);GO:0016504(peptidase activator activity);GO:0070851(growth factor receptor binding);GO:0001967(suckling behavior);GO:0006378(mRNA polyadenylation);GO:0006417(regulation of translation);GO:0006468(protein phosphorylation);GO:0006878(cellular copper ion homeostasis);GO:0006897(endocytosis);GO:0006979(response to oxidative stress);GO:0007176(regulation of epidermal growth factor-activated receptor activity);GO:0007409(axonogenesis);GO:0007617(mating behavior);GO:0007626(locomotory behavior);GO:0008088(axo-dendritic transport);GO:0008203(cholesterol metabolic process);GO:0008344(adult locomotory behavior);GO:0008542(visual learning);GO:0010288(response to lead ion);GO:0010468(regulation of gene expression);GO:0010952(positive regulation of peptidase activity);GO:0010971(positive regulation of G2/M transition of mitotic cell cycle);GO:0016199(axon midline choice point recognition);GO:0016322(neuron remodeling);GO:0016358(dendrite development);GO:0030198(extracellular matrix organization);GO:0030900(forebrain development);GO:0031175(neuron projection development);GO:0035235(ionotropic glutamate receptor signaling pathway);GO:0040014(regulation of multicellular organism growth);GO:0043393(regulation of protein binding);GO:0045665(negative regulation of neuron differentiation);GO:0045931(positive regulation of mitotic cell cycle);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0048669(collateral sprouting in absence of injury);GO:0050803(regulation of synapse structure or activity);GO:0050885(neuromuscular process controlling balance);GO:0051124(synaptic growth at neuromuscular junction);GO:0051247(positive regulation of protein metabolic process);GO:0051402(neuron apoptotic process);GO:0051563(smooth endoplasmic reticulum calcium ion homeostasis);GO:0071320(cellular response to cAMP);GO:0071874(cellular response to norepinephrine stimulus);GO:1990090(cellular response to nerve growth factor stimulus);GO:0005791(rough endoplasmic reticulum);GO:0005911(cell-cell junction);GO:0009986(cell surface);GO:0030134(ER to Golgi transport vesicle);GO:0030424(axon);GO:0030426(growth cone);GO:0031410(cytoplasmic vesicle);GO:0031594(neuromuscular junction);GO:0035253(ciliary rootlet);GO:0043005(neuron projection);GO:0043195(terminal bouton);GO:0044304(main axon);GO:0045177(apical part of cell);GO:0051233(spindle midzone);GO:0097449(astrocyte projection);GO:1990761(growth cone lamellipodium);GO:1990812(growth cone filopodium);GO:0005768(endosome);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0044267(cellular protein metabolic process);GO:0008285(negative regulation of cell proliferation);GO:0043687(post-translational protein modification);GO:0045087(innate immune response);GO:0005887(integral component of plasma membrane);GO:0031904(endosome lumen);GO:0032588(trans-Golgi network membrane);GO:0002576(platelet degranulation);GO:0010628(positive regulation of gene expression);GO:1904646(cellular response to amyloid-beta);GO:0005788(endoplasmic reticulum lumen);GO:0031093(platelet alpha granule lumen);GO:0005796(Golgi lumen);GO:0005102(receptor binding);GO:0043235(receptor complex);GO:0019899(enzyme binding);GO:0014005(microglia development);GO:0032640(tumor necrosis factor production);GO:0043197(dendritic spine);GO:0045202(synapse);GO:0007611(learning or memory);GO:0090647(modulation of age-related behavioral decline);GO:1900273(positive regulation of long-term synaptic potentiation);GO:0046330(positive regulation of JNK cascade);GO:0051425(PTB domain binding);GO:0001934(positive regulation of protein phosphorylation);GO:0002265(astrocyte activation involved in immune response);GO:0009987(cellular process);GO:0010629(negative regulation of gene expression);GO:0048143(astrocyte activation);GO:0048169(regulation of long-term neuronal synaptic plasticity);GO:0050808(synapse organization);GO:0051091(positive regulation of sequence-specific DNA binding transcription factor activity);GO:0098815(modulation of excitatory postsynaptic potential);GO:1990000(amyloid fibril formation);GO:2000310(regulation of NMDA receptor activity);GO:0005641(nuclear envelope lumen);GO:0043198(dendritic shaft);GO:0045121(membrane raft);GO:0045121(membrane raft)","04726(Serotonergic synapse);05010(Alzheimer's disease);05010(Alzheimer's disease)","K04520","NA","amyloid beta precursor protein [Source:HGNC Symbol;Acc:HGNC:620]",{"v":10.4277716771902,"d":"10.43"},{"v":10.4021418168903,"d":"10.40"},{"v":1.00246390221851,"d":"1.00"},{"v":3.55028752511163E-3,"d":"0.00"},{"v":0.964054204032622,"d":"0.96"},1,"up","no"]
["MSTRG.3785","RPLP0","ENST00000313104;ENST00000546989;ENST00000550856;ENST00000551150;ENST00000549098;ENST00000392514;ENST00000228306;ENST00000551258;ENST00000547191;ENST00000548495;ENST00000548568;ENST00000546990;ENST00000547173;ENST00000547211;ENST00000551783;ENST00000548551;ENST00000552292;ENST00000546564;ENST00000552902;ENST00000551914;ENST00000549242;ENST00000551336;ENST00000547475;ENST00000551217;ENST00000550423;ENST00000552461","GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0006412(translation);GO:0005783(endoplasmic reticulum);GO:0005829(cytosol);GO:0030529(intracellular ribonucleoprotein complex);GO:0005622(intracellular);GO:0005840(ribosome);GO:0005515(protein binding);GO:0003735(structural constituent of ribosome);GO:0042254(ribosome biogenesis);GO:0005925(focal adhesion);GO:0070062(extracellular exosome);GO:0016032(viral process);GO:0022625(cytosolic large ribosomal subunit);GO:0035722(interleukin-12-mediated signaling pathway);GO:0006413(translational initiation);GO:0006364(rRNA processing);GO:0036464(cytoplasmic ribonucleoprotein granule);GO:0000184(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay);GO:0019083(viral transcription);GO:0006614(SRP-dependent cotranslational protein targeting to membrane);GO:0006614(SRP-dependent cotranslational protein targeting to membrane)","03010(Ribosome);03010(Ribosome)","K02941","NA","ribosomal protein lateral stalk subunit P0 [Source:HGNC Symbol;Acc:HGNC:10371]",{"v":98.1253729032742,"d":"98.13"},{"v":98.0021548205449,"d":"98.00"},{"v":1.00125729972933,"d":"1.00"},{"v":0.00181276073127345,"d":"0.00"},{"v":0.965576324248392,"d":"0.97"},1,"up","no"]
["MSTRG.5353","CEMIP","ENST00000394685","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0016787(hydrolase activity);GO:0005783(endoplasmic reticulum);GO:0005886(plasma membrane);GO:0008152(metabolic process);GO:0005576(extracellular region);GO:0016798(hydrolase activity, acting on glycosyl bonds);GO:0004415(hyalurononglucosaminidase activity);GO:0005905(clathrin-coated pit);GO:0005515(protein binding);GO:0010800(positive regulation of peptidyl-threonine phosphorylation);GO:0030335(positive regulation of cell migration);GO:0090314(positive regulation of protein targeting to membrane);GO:0007605(sensory perception of sound);GO:0030213(hyaluronan biosynthetic process);GO:0005540(hyaluronic acid binding);GO:0051281(positive regulation of release of sequestered calcium ion into cytosol);GO:0030214(hyaluronan catabolic process);GO:0045334(clathrin-coated endocytic vesicle);GO:0032050(clathrin heavy chain binding);GO:0046923(ER retention sequence binding);GO:1900020(positive regulation of protein kinase C activity);GO:0030665(clathrin-coated vesicle membrane)","NA","NA","NA","cell migration inducing hyaluronan binding protein [Source:HGNC Symbol;Acc:HGNC:29213]",{"v":0.158125784017845,"d":"0.16"},{"v":0.156791658050125,"d":"0.16"},{"v":1.00850890911105,"d":"1.01"},{"v":0.0122238286941213,"d":"0.01"},{"v":0.966250249928293,"d":"0.97"},1,"up","no"]
["ENSG00000137807","KIF23","ENST00000260363;ENST00000558303;ENST00000395392;ENST00000558346;ENST00000559944;ENST00000560042;ENST00000560125","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0005654(nucleoplasm);GO:0051301(cell division);GO:0003777(microtubule motor activity);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0007049(cell cycle);GO:0008017(microtubule binding);GO:0005874(microtubule);GO:0007018(microtubule-based movement);GO:0005925(focal adhesion);GO:0005819(spindle);GO:0030496(midbody);GO:0000910(cytokinesis);GO:0072383(plus-end-directed vesicle transport along microtubule);GO:0005829(cytosol);GO:0006890(retrograde vesicle-mediated transport, Golgi to ER);GO:0016887(ATPase activity);GO:0000915(actomyosin contractile ring assembly);GO:0019886(antigen processing and presentation of exogenous peptide antigen via MHC class II);GO:0000281(mitotic cytokinesis);GO:0032467(positive regulation of cytokinesis);GO:0005871(kinesin complex);GO:0005813(centrosome);GO:0000022(mitotic spindle elongation);GO:0072686(mitotic spindle);GO:0051256(mitotic spindle midzone assembly);GO:0097149(centralspindlin complex);GO:0003774(motor activity);GO:0005622(intracellular);GO:0005623(cell);GO:0045171(intercellular bridge);GO:0045171(intercellular bridge)","05206(MicroRNAs in cancer);05206(MicroRNAs in cancer)","K17387","NA","kinesin family member 23 [Source:HGNC Symbol;Acc:HGNC:6392]",{"v":0.195493514505253,"d":"0.20"},{"v":0.197209550885997,"d":"0.20"},{"v":0.991298411395217,"d":"0.99"},{"v":-0.0126086763917164,"d":"-0.01"},{"v":0.968085598777832,"d":"0.97"},1,"down","no"]
["MSTRG.3721","TCTN1","ENST00000551590;ENST00000485445;ENST00000551555;ENST00000482281;ENST00000397655;ENST00000546643;ENST00000481093;ENST00000495659;ENST00000478122;ENST00000397656;ENST00000480648;ENST00000490514;ENST00000463313;ENST00000552038;ENST00000481720;ENST00000460357;ENST00000464809;ENST00000550703","GO:0005737(cytoplasm);GO:0005856(cytoskeleton);GO:0042995(cell projection);GO:0005576(extracellular region);GO:0007275(multicellular organism development);GO:0060271(cilium assembly);GO:0005829(cytosol);GO:0030030(cell projection organization);GO:0097711(ciliary basal body docking);GO:0036038(MKS complex);GO:0001701(in utero embryonic development);GO:0001841(neural tube formation);GO:0008589(regulation of smoothened signaling pathway);GO:0021523(somatic motor neuron differentiation);GO:0021537(telencephalon development);GO:0021904(dorsal/ventral neural tube patterning);GO:0021956(central nervous system interneuron axonogenesis);GO:1904491(protein localization to ciliary transition zone);GO:0005615(extracellular space);GO:0016020(membrane);GO:0035869(ciliary transition zone);GO:0035869(ciliary transition zone)","NA","NA","NA","tectonic family member 1 [Source:HGNC Symbol;Acc:HGNC:26113]",{"v":0.276134291514836,"d":"0.28"},{"v":0.291866626548673,"d":"0.29"},{"v":0.946097519884777,"d":"0.95"},{"v":-0.0799391965204135,"d":"-0.08"},{"v":0.969945066461325,"d":"0.97"},1,"down","no"]
["MSTRG.10242","DDT;AC253536.5","ENST00000398344;ENST00000506097;ENST00000403754;ENST00000428792;ENST00000444947","GO:0005737(cytoplasm);GO:0016829(lyase activity);GO:0070062(extracellular exosome);GO:0042438(melanin biosynthetic process);GO:0004167(dopachrome isomerase activity);GO:0033981(D-dopachrome decarboxylase activity);GO:0033981(D-dopachrome decarboxylase activity)","NA","NA","NA","D-dopachrome tautomerase [Source:HGNC Symbol;Acc:HGNC:2732]",{"v":4.06075237603306,"d":"4.06"},{"v":4.0537350428719,"d":"4.05"},{"v":1.00173107839732,"d":"1.00"},{"v":0.00249525909721464,"d":"0.00"},{"v":0.970415086258207,"d":"0.97"},1,"up","no"]
["MSTRG.3227","ATF7IP","ENST00000261168;ENST00000543189;ENST00000536444;ENST00000540793;ENST00000396279;ENST00000545723;ENST00000541654;ENST00000539659;ENST00000535132;ENST00000541056;ENST00000544627;ENST00000535179;ENST00000538511;ENST00000542508","GO:0005634(nucleus);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0005515(protein binding);GO:0016604(nuclear body);GO:0045893(positive regulation of transcription, DNA-templated);GO:0016032(viral process);GO:0045892(negative regulation of transcription, DNA-templated);GO:0006306(DNA methylation);GO:0045898(regulation of RNA polymerase II transcriptional preinitiation complex assembly);GO:0003714(transcription corepressor activity);GO:0016887(ATPase activity);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0005667(transcription factor complex);GO:0005667(transcription factor complex)","NA","NA","NA","activating transcription factor 7 interacting protein [Source:HGNC Symbol;Acc:HGNC:20092]",{"v":4.41002600113731,"d":"4.41"},{"v":4.5626209459398,"d":"4.56"},{"v":0.966555419218359,"d":"0.97"},{"v":-0.0490756405270784,"d":"-0.05"},{"v":0.971721398381288,"d":"0.97"},1,"down","no"]
["ENSG00000181026","AEN","ENST00000332810;ENST00000557927;ENST00000560174;ENST00000558327;ENST00000557787","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0005730(nucleolus);GO:0016787(hydrolase activity);GO:0031965(nuclear membrane);GO:0090305(nucleic acid phosphodiester bond hydrolysis);GO:0005515(protein binding);GO:0006974(cellular response to DNA damage stimulus);GO:0006915(apoptotic process);GO:0004527(exonuclease activity);GO:0004518(nuclease activity);GO:0005654(nucleoplasm);GO:0042771(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator);GO:0010212(response to ionizing radiation);GO:0010212(response to ionizing radiation)","NA","NA","NA","apoptosis enhancing nuclease [Source:HGNC Symbol;Acc:HGNC:25722]",{"v":1.89738171784646,"d":"1.90"},{"v":1.90201649767365,"d":"1.90"},{"v":0.997563228377431,"d":"1.00"},{"v":-0.00351980856427462,"d":"-0.00"},{"v":0.971818815648672,"d":"0.97"},1,"down","no"]
["ENSG00000092148","HECTD1","ENST00000399332;ENST00000553957;ENST00000554027;ENST00000556281;ENST00000554882;ENST00000555311;ENST00000556224;ENST00000556004;ENST00000557321;ENST00000557695;ENST00000555843;ENST00000554471;ENST00000554850;ENST00000553616;ENST00000553700","GO:0016740(transferase activity);GO:0016567(protein ubiquitination);GO:0004842(ubiquitin-protein transferase activity);GO:0046872(metal ion binding);GO:0005737(cytoplasm);GO:0061630(ubiquitin protein ligase activity);GO:0005515(protein binding);GO:0005515(protein binding)","NA","NA","NA","HECT domain E3 ubiquitin protein ligase 1 [Source:HGNC Symbol;Acc:HGNC:20157]",{"v":2.76716704196528,"d":"2.77"},{"v":2.86261693016404,"d":"2.86"},{"v":0.966656422941895,"d":"0.97"},{"v":-0.0489248887387733,"d":"-0.05"},{"v":0.973415325925102,"d":"0.97"},1,"down","no"]
["ENSG00000171291","ZNF439","ENST00000304030;ENST00000455282;ENST00000442091;ENST00000592495","GO:0003676(nucleic acid binding);GO:0006355(regulation of transcription, DNA-templated);GO:0005622(intracellular);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0005515(protein binding)","NA","NA","NA","zinc finger protein 439 [Source:HGNC Symbol;Acc:HGNC:20873]",{"v":0.626379765123872,"d":"0.63"},{"v":0.625813008258114,"d":"0.63"},{"v":1.00090563292594,"d":"1.00"},{"v":1.30596085975591E-3,"d":"0.00"},{"v":0.974324655766589,"d":"0.97"},1,"up","no"]
["ENSG00000115392","FANCL","ENST00000402135;ENST00000233741;ENST00000449070;ENST00000427708;ENST00000470506","GO:0043231(intracellular membrane-bounded organelle);GO:0016567(protein ubiquitination);GO:0004842(ubiquitin-protein transferase activity);GO:0006281(DNA repair);GO:0016604(nuclear body);GO:0043240(Fanconi anaemia nuclear complex);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0016740(transferase activity);GO:0005515(protein binding);GO:0006974(cellular response to DNA damage stimulus);GO:0005654(nucleoplasm);GO:0031625(ubiquitin protein ligase binding);GO:0036297(interstrand cross-link repair);GO:0061630(ubiquitin protein ligase activity);GO:0006513(protein monoubiquitination);GO:0007276(gamete generation);GO:0042127(regulation of cell proliferation);GO:0005635(nuclear envelope);GO:0005635(nuclear envelope)","04120(Ubiquitin mediated proteolysis);03460(Fanconi anemia pathway);03460(Fanconi anemia pathway)","K10606","EC:2.3.2.27","Fanconi anemia complementation group L [Source:HGNC Symbol;Acc:HGNC:20748]",{"v":0.677387361525705,"d":"0.68"},{"v":0.677959786898839,"d":"0.68"},{"v":0.999155664710215,"d":"1.00"},{"v":-1.21863287521935E-3,"d":"-0.00"},{"v":0.974907126198355,"d":"0.97"},1,"down","no"]
["MSTRG.1477","ARID4B;RBM34","ENST00000264183;ENST00000421364;ENST00000408888;ENST00000471257;ENST00000494543;ENST00000491632;ENST00000366603;ENST00000495224;ENST00000418304;ENST00000462969;ENST00000447801;ENST00000475960;ENST00000486751;ENST00000468751;ENST00000429912;ENST00000485019;ENST00000444620;ENST00000476261;ENST00000349213;ENST00000466653;ENST00000474401;ENST00000474086","GO:0006355(regulation of transcription, DNA-templated);GO:0005634(nucleus);GO:0003677(DNA binding);GO:0005737(cytoplasm);GO:0006351(transcription, DNA-templated);GO:0016575(histone deacetylation);GO:0005515(protein binding);GO:0003674(molecular_function);GO:0008150(biological_process);GO:0005575(cellular_component);GO:0005654(nucleoplasm);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0004407(histone deacetylase activity);GO:0044212(transcription regulatory region DNA binding);GO:0006349(regulation of gene expression by genetic imprinting);GO:0007283(spermatogenesis);GO:0034773(histone H4-K20 trimethylation);GO:0036124(histone H3-K9 trimethylation);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0097368(establishment of Sertoli cell barrier);GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0005730(nucleolus);GO:0005730(nucleolus)","NA","NA","NA","AT-rich interaction domain 4B [Source:HGNC Symbol;Acc:HGNC:15550];RNA binding motif protein 34 [Source:HGNC Symbol;Acc:HGNC:28965]",{"v":3.88410162147342,"d":"3.88"},{"v":3.90153583771756,"d":"3.90"},{"v":0.995531447878654,"d":"1.00"},{"v":-0.00646120487631016,"d":"-0.01"},{"v":0.976228456239382,"d":"0.98"},1,"down","no"]
["MSTRG.7998","FKBP8","ENST00000597547;ENST00000544835;ENST00000596015;MSTRG.7998.8;ENST00000594844;ENST00000606531;MSTRG.7998.7;ENST00000599540;ENST00000601844;ENST00000597611;ENST00000222308;ENST00000596558;ENST00000608443;MSTRG.7998.6;ENST00000597960;ENST00000609656;ENST00000596494","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0046872(metal ion binding);GO:0016853(isomerase activity);GO:0005783(endoplasmic reticulum);GO:0005829(cytosol);GO:0005739(mitochondrion);GO:0003755(peptidyl-prolyl cis-trans isomerase activity);GO:0005515(protein binding);GO:0006915(apoptotic process);GO:0000413(protein peptidyl-prolyl isomerization);GO:0042802(identical protein binding);GO:0005528(FK506 binding);GO:0061077(chaperone-mediated protein folding);GO:0005737(cytoplasm);GO:0031966(mitochondrial membrane);GO:0016032(viral process);GO:0043234(protein complex);GO:0035556(intracellular signal transduction);GO:0097718(disordered domain specific binding);GO:0001933(negative regulation of protein phosphorylation);GO:0001708(cell fate specification);GO:0007224(smoothened signaling pathway);GO:0009953(dorsal/ventral pattern formation);GO:0010468(regulation of gene expression);GO:0021904(dorsal/ventral neural tube patterning);GO:0021915(neural tube development);GO:0030510(regulation of BMP signaling pathway);GO:0030513(positive regulation of BMP signaling pathway);GO:0035264(multicellular organism growth);GO:0043010(camera-type eye development);GO:0043066(negative regulation of apoptotic process);GO:0005740(mitochondrial envelope);GO:0030176(integral component of endoplasmic reticulum membrane);GO:0030176(integral component of endoplasmic reticulum membrane)","NA","NA","NA","FK506 binding protein 8 [Source:HGNC Symbol;Acc:HGNC:3724]",{"v":934.508018789403,"d":"934.51"},{"v":964.549105164698,"d":"964.55"},{"v":0.968854787989083,"d":"0.97"},{"v":-0.0456476442593159,"d":"-0.05"},{"v":0.976465187328605,"d":"0.98"},1,"down","no"]
["MSTRG.6284","PITPNA-AS1","ENST00000425081","NA","NA","NA","NA","PITPNA antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:44116]",{"v":1.680208,"d":"1.68"},{"v":1.660669,"d":"1.66"},{"v":1.01176574019266,"d":"1.01"},{"v":0.016875293406892,"d":"0.02"},{"v":0.97793655170897,"d":"0.98"},1,"up","no"]
["ENSG00000234545","FAM133B","ENST00000445716;ENST00000438306;ENST00000481407;ENST00000468931;ENST00000427372;ENST00000415397;ENST00000480397;ENST00000494079;ENST00000490747","GO:0003723(RNA binding);GO:0003723(RNA binding)","NA","NA","NA","family with sequence similarity 133 member B [Source:HGNC Symbol;Acc:HGNC:28629]",{"v":1.09260204213357,"d":"1.09"},{"v":1.12616110085164,"d":"1.13"},{"v":0.97020048135858,"d":"0.97"},{"v":-0.0436451995708091,"d":"-0.04"},{"v":0.97892461192005,"d":"0.98"},1,"down","no"]
["ENSG00000144036","EXOC6B","ENST00000272427;ENST00000471335;ENST00000634650;ENST00000410104","GO:0006810(transport);GO:0015031(protein transport);GO:0000145(exocyst);GO:0005515(protein binding);GO:0006904(vesicle docking involved in exocytosis);GO:0006887(exocytosis);GO:0006887(exocytosis)","NA","NA","NA","exocyst complex component 6B [Source:HGNC Symbol;Acc:HGNC:17085]",{"v":0.419588122585074,"d":"0.42"},{"v":0.421478589977444,"d":"0.42"},{"v":0.99551467752497,"d":"1.00"},{"v":-6.4855081868024E-3,"d":"-0.01"},{"v":0.980449703049938,"d":"0.98"},1,"down","no"]
["MSTRG.6384","PHF23","ENST00000571362;ENST00000320316;ENST00000573826;ENST00000572789;ENST00000574236;ENST00000613632;ENST00000576955;ENST00000570899;ENST00000574407;ENST00000454255;ENST00000574899;ENST00000574323;ENST00000570753","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0005654(nucleoplasm);GO:0006914(autophagy);GO:0003682(chromatin binding);GO:0005515(protein binding);GO:1902902(negative regulation of autophagosome assembly);GO:0007076(mitotic chromosome condensation);GO:0031398(positive regulation of protein ubiquitination);GO:1901097(negative regulation of autophagosome maturation);GO:1901097(negative regulation of autophagosome maturation)","NA","NA","NA","PHD finger protein 23 [Source:HGNC Symbol;Acc:HGNC:28428]",{"v":7.82671163241107,"d":"7.83"},{"v":8.07335014372979,"d":"8.07"},{"v":0.969450289294058,"d":"0.97"},{"v":-0.0447611720350719,"d":"-0.04"},{"v":0.98211664623571,"d":"0.98"},1,"down","no"]
["MSTRG.1080","CCT3","ENST00000295688;ENST00000368262;ENST00000413555;ENST00000496684;ENST00000490221;ENST00000472765;ENST00000368258;ENST00000368259;ENST00000478640;ENST00000368256;ENST00000415548;ENST00000533194;ENST00000446905;ENST00000368261;ENST00000489870","GO:0003723(RNA binding);GO:0005737(cytoplasm);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0006457(protein folding);GO:0005515(protein binding);GO:0005874(microtubule);GO:0051082(unfolded protein binding);GO:0061077(chaperone-mediated protein folding);GO:0070062(extracellular exosome);GO:0005856(cytoskeleton);GO:0050821(protein stabilization);GO:0032212(positive regulation of telomere maintenance via telomerase);GO:1904874(positive regulation of telomerase RNA localization to Cajal body);GO:0044183(protein binding involved in protein folding);GO:0006458('de novo' protein folding);GO:1904871(positive regulation of protein localization to Cajal body);GO:0005832(chaperonin-containing T-complex);GO:0007339(binding of sperm to zona pellucida);GO:0046931(pore complex assembly);GO:1901998(toxin transport);GO:0002199(zona pellucida receptor complex);GO:0043209(myelin sheath);GO:0044297(cell body);GO:0044297(cell body)","NA","NA","NA","chaperonin containing TCP1 subunit 3 [Source:HGNC Symbol;Acc:HGNC:1616]",{"v":12.4361277914385,"d":"12.44"},{"v":12.5459485316078,"d":"12.55"},{"v":0.991246517559623,"d":"0.99"},{"v":-0.0126842025280348,"d":"-0.01"},{"v":0.983415651277814,"d":"0.98"},1,"down","no"]
["MSTRG.11131","GTF2E1","ENST00000283875;ENST00000497393;ENST00000484715;ENST00000469772","GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0043565(sequence-specific DNA binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0005829(cytosol);GO:0005515(protein binding);GO:0006367(transcription initiation from RNA polymerase II promoter);GO:0005654(nucleoplasm);GO:0016032(viral process);GO:0006366(transcription from RNA polymerase II promoter);GO:0006368(transcription elongation from RNA polymerase II promoter);GO:0042795(snRNA transcription from RNA polymerase II promoter);GO:0005669(transcription factor TFIID complex);GO:0097550(transcriptional preinitiation complex);GO:0097550(transcriptional preinitiation complex)","03022(Basal transcription factors);05203(Viral carcinogenesis);05169(Epstein-Barr virus infection);05169(Epstein-Barr virus infection)","K03136","NA","general transcription factor IIE subunit 1 [Source:HGNC Symbol;Acc:HGNC:4650]",{"v":3.57467824451039,"d":"3.57"},{"v":3.67501239406528,"d":"3.68"},{"v":0.9726982826733,"d":"0.97"},{"v":-0.0399357242014412,"d":"-0.04"},{"v":0.984402170815441,"d":"0.98"},1,"down","no"]
["MSTRG.9276","TTC30B","ENST00000408939","GO:0042995(cell projection);GO:0005515(protein binding);GO:0035735(intraciliary transport involved in cilium assembly);GO:0005929(cilium);GO:0097542(ciliary tip);GO:0030030(cell projection organization);GO:0060271(cilium assembly);GO:0030992(intraciliary transport particle B);GO:0042073(intraciliary transport)","NA","NA","NA","tetratricopeptide repeat domain 30B [Source:HGNC Symbol;Acc:HGNC:26425]",{"v":0.326685,"d":"0.33"},{"v":0.338585,"d":"0.34"},{"v":0.964853729491856,"d":"0.96"},{"v":-0.0516178465287945,"d":"-0.05"},{"v":0.984797883911388,"d":"0.98"},1,"down","no"]
["MSTRG.8541","FAM228B;AC008073.3;FAM228A","ENST00000469867;ENST00000613899;ENST00000611138;ENST00000611917;ENST00000461972;ENST00000615135;ENST00000610442;ENST00000415196;ENST00000460686;ENST00000611127;ENST00000615575;ENST00000486967;ENST00000456591;ENST00000295150","NA","NA","NA","NA","family with sequence similarity 228 member B [Source:HGNC Symbol;Acc:HGNC:24736];family with sequence similarity 228 member A [Source:HGNC Symbol;Acc:HGNC:34418]",{"v":0.340066486657136,"d":"0.34"},{"v":0.356899596854896,"d":"0.36"},{"v":0.952835166119272,"d":"0.95"},{"v":-0.0697014354115588,"d":"-0.07"},{"v":0.98598631189424,"d":"0.99"},1,"down","no"]
["ENSG00000197283","SYNGAP1","ENST00000449372;ENST00000629380;ENST00000638142;ENST00000470232;ENST00000636146;ENST00000418600;ENST00000636640;ENST00000293748;ENST00000637194;ENST00000636731;ENST00000636905;ENST00000479510;ENST00000628646;ENST00000637721;ENST00000636436;ENST00000428982","GO:0007165(signal transduction);GO:0043547(positive regulation of GTPase activity);GO:0043087(regulation of GTPase activity);GO:0005096(GTPase activator activity);GO:0005737(cytoplasm);GO:0007265(Ras protein signal transduction);GO:0007389(pattern specification process);GO:0008542(visual learning);GO:0016358(dendrite development);GO:0043113(receptor clustering);GO:0043408(regulation of MAPK cascade);GO:0043524(negative regulation of neuron apoptotic process);GO:0048169(regulation of long-term neuronal synaptic plasticity);GO:0050771(negative regulation of axonogenesis);GO:0050803(regulation of synapse structure or activity);GO:0014069(postsynaptic density);GO:0016020(membrane);GO:0043198(dendritic shaft);GO:0005829(cytosol);GO:0000165(MAPK cascade);GO:0017124(SH3 domain binding);GO:0046580(negative regulation of Ras protein signal transduction);GO:0031235(intrinsic component of the cytoplasmic side of the plasma membrane);GO:0048167(regulation of synaptic plasticity);GO:0048167(regulation of synaptic plasticity)","04014(Ras signaling pathway);04014(Ras signaling pathway)","K17631","NA","synaptic Ras GTPase activating protein 1 [Source:HGNC Symbol;Acc:HGNC:11497]",{"v":1.91432208644012,"d":"1.91"},{"v":1.9666917000165,"d":"1.97"},{"v":0.973371721873876,"d":"0.97"},{"v":-0.0389372324395593,"d":"-0.04"},{"v":0.986857570903384,"d":"0.99"},1,"down","no"]
["MSTRG.13304","NHSL1","ENST00000427025;ENST00000343505;ENST00000491526;ENST00000342260","GO:0016020(membrane);GO:0097475(motor neuron migration);GO:0097475(motor neuron migration)","NA","NA","NA","NHS like 1 [Source:HGNC Symbol;Acc:HGNC:21021]",{"v":0.199871607138771,"d":"0.20"},{"v":0.206464396407734,"d":"0.21"},{"v":0.968068154201544,"d":"0.97"},{"v":-0.0468194747972809,"d":"-0.05"},{"v":0.988478314366498,"d":"0.99"},1,"down","no"]
["ENSG00000124198","ARFGEF2","ENST00000371917;ENST00000493140","GO:0006810(transport);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0015031(protein transport);GO:0005794(Golgi apparatus);GO:0043547(positive regulation of GTPase activity);GO:0005856(cytoskeleton);GO:0042995(cell projection);GO:0005515(protein binding);GO:0000139(Golgi membrane);GO:0048471(perinuclear region of cytoplasm);GO:0030054(cell junction);GO:0045202(synapse);GO:0031410(cytoplasmic vesicle);GO:0005086(ARF guanyl-nucleotide exchange factor activity);GO:0032012(regulation of ARF protein signal transduction);GO:0005085(guanyl-nucleotide exchange factor activity);GO:0030425(dendrite);GO:0005815(microtubule organizing center);GO:0005768(endosome);GO:0005802(trans-Golgi network);GO:0043197(dendritic spine);GO:0055037(recycling endosome);GO:0005829(cytosol);GO:0006887(exocytosis);GO:0035556(intracellular signal transduction);GO:0034237(protein kinase A regulatory subunit binding);GO:0006893(Golgi to plasma membrane transport);GO:0007032(endosome organization);GO:0050811(GABA receptor binding);GO:0032760(positive regulation of tumor necrosis factor production);GO:0032279(asymmetric synapse);GO:0001881(receptor recycling);GO:0005879(axonemal microtubule);GO:0017022(myosin binding);GO:0010256(endomembrane system organization);GO:0032280(symmetric synapse);GO:0032280(symmetric synapse)","04144(Endocytosis);04144(Endocytosis)","K18442","NA","ADP ribosylation factor guanine nucleotide exchange factor 2 [Source:HGNC Symbol;Acc:HGNC:15853]",{"v":2.83694809323645,"d":"2.84"},{"v":2.90704390229178,"d":"2.91"},{"v":0.975887598739025,"d":"0.98"},{"v":-0.0352131049682114,"d":"-0.04"},{"v":0.990269913165465,"d":"0.99"},1,"down","no"]
["ENSG00000156502","SUPV3L1","ENST00000359655;ENST00000497254;ENST00000483572;ENST00000486661;ENST00000471069","GO:0003723(RNA binding);GO:0005634(nucleus);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0016787(hydrolase activity);GO:0005739(mitochondrion);GO:0004386(helicase activity);GO:0003677(DNA binding);GO:0042803(protein homodimerization activity);GO:0005515(protein binding);GO:0006310(DNA recombination);GO:0005759(mitochondrial matrix);GO:0016817(hydrolase activity, acting on acid anhydrides);GO:0043066(negative regulation of apoptotic process);GO:0042645(mitochondrial nucleoid);GO:0030307(positive regulation of cell growth);GO:0004004(ATP-dependent RNA helicase activity);GO:0006401(RNA catabolic process);GO:0003725(double-stranded RNA binding);GO:0003678(DNA helicase activity);GO:0032508(DNA duplex unwinding);GO:0070584(mitochondrion morphogenesis);GO:0034458(3'-5' RNA helicase activity);GO:0000958(mitochondrial mRNA catabolic process);GO:0000962(positive regulation of mitochondrial RNA catabolic process);GO:0000965(mitochondrial RNA 3'-end processing);GO:0035945(mitochondrial ncRNA surveillance);GO:0035946(mitochondrial mRNA surveillance);GO:0070827(chromatin maintenance);GO:2000827(mitochondrial RNA surveillance);GO:0045025(mitochondrial degradosome);GO:0045025(mitochondrial degradosome)","NA","NA","NA","Suv3 like RNA helicase [Source:HGNC Symbol;Acc:HGNC:11471]",{"v":1.54069141629699,"d":"1.54"},{"v":1.55884870441279,"d":"1.56"},{"v":0.98835211649187,"d":"0.99"},{"v":-0.016902977961167,"d":"-0.02"},{"v":0.990475672693873,"d":"0.99"},1,"down","no"]
["ENSG00000182518","FAM104B","ENST00000358460;ENST00000425133;ENST00000477847;ENST00000332132;ENST00000478918;ENST00000489298;ENST00000472571","NA","NA","NA","NA","family with sequence similarity 104 member B [Source:HGNC Symbol;Acc:HGNC:25085]",{"v":1.03228054981993,"d":"1.03"},{"v":1.03748920848339,"d":"1.04"},{"v":0.99497955388753,"d":"0.99"},{"v":-0.00726121526940774,"d":"-0.01"},{"v":0.991989180860268,"d":"0.99"},1,"down","no"]
["MSTRG.1020","FLAD1","ENST00000368431;ENST00000315144;ENST00000368428;ENST00000295530;ENST00000368432;ENST00000368433;ENST00000292180;ENST00000489992;ENST00000481758;ENST00000477609","GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0003919(FMN adenylyltransferase activity);GO:0006747(FAD biosynthetic process);GO:0005737(cytoplasm);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0016740(transferase activity);GO:0003824(catalytic activity);GO:0008152(metabolic process);GO:0005739(mitochondrion);GO:0005515(protein binding);GO:0005759(mitochondrial matrix);GO:0016779(nucleotidyltransferase activity);GO:0055114(oxidation-reduction process);GO:0006771(riboflavin metabolic process);GO:0006771(riboflavin metabolic process)","00740(Riboflavin metabolism);00740(Riboflavin metabolism)","K00953","EC:2.7.7.2","flavin adenine dinucleotide synthetase 1 [Source:HGNC Symbol;Acc:HGNC:24671]",{"v":2.06381215376959,"d":"2.06"},{"v":2.11962107812889,"d":"2.12"},{"v":0.973670329600343,"d":"0.97"},{"v":-0.0384947151460098,"d":"-0.04"},{"v":0.992491523361344,"d":"0.99"},1,"down","no"]
["MSTRG.5605","HMOX2","ENST00000458134;ENST00000570646;ENST00000574594;ENST00000570622;ENST00000619528;ENST00000398595;ENST00000575120;ENST00000406590;ENST00000574466;ENST00000613539;ENST00000572812;ENST00000570445;ENST00000619913","GO:0046872(metal ion binding);GO:0055114(oxidation-reduction process);GO:0004392(heme oxygenase (decyclizing) activity);GO:0006788(heme oxidation);GO:0016020(membrane);GO:0016491(oxidoreductase activity);GO:0005783(endoplasmic reticulum);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0005789(endoplasmic reticulum membrane);GO:0043231(intracellular membrane-bounded organelle);GO:0001666(response to hypoxia);GO:0043312(neutrophil degranulation);GO:0035579(specific granule membrane);GO:0020037(heme binding);GO:0006979(response to oxidative stress);GO:0006879(cellular iron ion homeostasis);GO:0042167(heme catabolic process);GO:0055072(iron ion homeostasis);GO:0016021(integral component of membrane);GO:0016021(integral component of membrane)","00860(Porphyrin and chlorophyll metabolism);04978(Mineral absorption);04978(Mineral absorption)","K21418","EC:1.14.14.18","heme oxygenase 2 [Source:HGNC Symbol;Acc:HGNC:5014]",{"v":7.23066202900079,"d":"7.23"},{"v":7.3316432578434,"d":"7.33"},{"v":0.986226658159536,"d":"0.99"},{"v":-0.0200088448116979,"d":"-0.02"},{"v":0.994146778642101,"d":"0.99"},1,"down","no"]
["MSTRG.14243","SLC25A37","MSTRG.14243.10;ENST00000519973;MSTRG.14243.3;ENST00000519192;ENST00000520949;MSTRG.14243.2;ENST00000520654;ENST00000290075;ENST00000518881;ENST00000523883;ENST00000522164;ENST00000521637;ENST00000517923;ENST00000417331;ENST00000523930","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005743(mitochondrial inner membrane);GO:0005739(mitochondrion);GO:0006811(ion transport);GO:0006839(mitochondrial transport);GO:0055072(iron ion homeostasis);GO:0034755(iron ion transmembrane transport);GO:0005381(iron ion transmembrane transporter activity);GO:0048250(mitochondrial iron ion transport);GO:0048250(mitochondrial iron ion transport)","NA","NA","NA","solute carrier family 25 member 37 [Source:HGNC Symbol;Acc:HGNC:29786]",{"v":69.6660510889367,"d":"69.67"},{"v":71.1094094455251,"d":"71.11"},{"v":0.979702287392864,"d":"0.98"},{"v":-0.029584686225828,"d":"-0.03"},{"v":0.996189044275712,"d":"1.00"},1,"down","no"]
["MSTRG.10345","AP1B1;AC000041.1","ENST00000432560;ENST00000317368;ENST00000415447;ENST00000482818;MSTRG.10345.6;ENST00000415756;ENST00000473606;ENST00000472057;ENST00000439655;ENST00000402502;ENST00000357586;ENST00000405198","GO:0006810(transport);GO:0016020(membrane);GO:0008565(protein transporter activity);GO:0006886(intracellular protein transport);GO:0015031(protein transport);GO:0016192(vesicle-mediated transport);GO:0005794(Golgi apparatus);GO:0030117(membrane coat);GO:0043231(intracellular membrane-bounded organelle);GO:0005829(cytosol);GO:0030131(clathrin adaptor complex);GO:0005515(protein binding);GO:0031410(cytoplasmic vesicle);GO:0019886(antigen processing and presentation of exogenous peptide antigen via MHC class II);GO:0005215(transporter activity);GO:0032588(trans-Golgi network membrane);GO:0030665(clathrin-coated vesicle membrane);GO:0000139(Golgi membrane);GO:0005765(lysosomal membrane);GO:0050690(regulation of defense response to virus by virus);GO:0030659(cytoplasmic vesicle membrane);GO:0030669(clathrin-coated endocytic vesicle membrane);GO:0019901(protein kinase binding);GO:0007368(determination of left/right symmetry);GO:0007507(heart development);GO:0007507(heart development)","04142(Lysosome);04142(Lysosome)","K12392","NA","adaptor related protein complex 1 beta 1 subunit [Source:HGNC Symbol;Acc:HGNC:554]",{"v":8.69144790512249,"d":"8.69"},{"v":8.87604293615442,"d":"8.88"},{"v":0.97920300382054,"d":"0.98"},{"v":-0.0303201112130584,"d":"-0.03"},{"v":0.996816421806575,"d":"1.00"},1,"down","no"]
["ENSG00000112367","FIG4","ENST00000230124;ENST00000415980;ENST00000419951;ENST00000368941","GO:0016020(membrane);GO:0043231(intracellular membrane-bounded organelle);GO:0016787(hydrolase activity);GO:0016311(dephosphorylation);GO:0005515(protein binding);GO:0005811(lipid particle);GO:0036092(phosphatidylinositol-3-phosphate biosynthetic process);GO:0042578(phosphoric ester hydrolase activity);GO:0005768(endosome);GO:0010008(endosome membrane);GO:0006661(phosphatidylinositol biosynthetic process);GO:0000139(Golgi membrane);GO:0043813(phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity);GO:0031901(early endosome membrane);GO:0031902(late endosome membrane);GO:0004438(phosphatidylinositol-3-phosphatase activity);GO:0034593(phosphatidylinositol bisphosphate phosphatase activity);GO:0043812(phosphatidylinositol-4-phosphate phosphatase activity);GO:0007033(vacuole organization);GO:0007626(locomotory behavior);GO:0010976(positive regulation of neuron projection development);GO:0031642(negative regulation of myelination);GO:0032288(myelin assembly);GO:0043473(pigmentation);GO:0046488(phosphatidylinositol metabolic process);GO:0048666(neuron development);GO:0005783(endoplasmic reticulum);GO:0005794(Golgi apparatus);GO:0055037(recycling endosome);GO:0016021(integral component of membrane);GO:0016021(integral component of membrane)","NA","NA","NA","FIG4 phosphoinositide 5-phosphatase [Source:HGNC Symbol;Acc:HGNC:16873]",{"v":3.14830310885301,"d":"3.15"},{"v":3.19887074860802,"d":"3.20"},{"v":0.984192034086712,"d":"0.98"},{"v":-0.0229882553448389,"d":"-0.02"},{"v":0.99856065929666,"d":"1.00"},1,"down","no"]
["MSTRG.10927","QARS","ENST00000464962;ENST00000306125;ENST00000634609;ENST00000635443;ENST00000494984;ENST00000453392;ENST00000494838;ENST00000470113;ENST00000634953;ENST00000634527;ENST00000634432;ENST00000635278;ENST00000418549;ENST00000634802;ENST00000635194;ENST00000478561;ENST00000417025;ENST00000482468;ENST00000470619;ENST00000497635;ENST00000430182;ENST00000635052;ENST00000634359;ENST00000459870;ENST00000635501;ENST00000487495;ENST00000635292;ENST00000635375;ENST00000494767;ENST00000637113;ENST00000635622;ENST00000470225;ENST00000637543;ENST00000482438;ENST00000482261;ENST00000634602;ENST00000452739;ENST00000635541;ENST00000482248;ENST00000634724;ENST00000635231;ENST00000637281;ENST00000636669","GO:0005737(cytoplasm);GO:0006412(translation);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0005829(cytosol);GO:0016874(ligase activity);GO:0004812(aminoacyl-tRNA ligase activity);GO:0006418(tRNA aminoacylation for protein translation);GO:0016876(ligase activity, forming aminoacyl-tRNA and related compounds);GO:0043039(tRNA aminoacylation);GO:0005515(protein binding);GO:0004819(glutamine-tRNA ligase activity);GO:0006425(glutaminyl-tRNA aminoacylation);GO:0005759(mitochondrial matrix);GO:0043234(protein complex);GO:0007420(brain development);GO:0017101(aminoacyl-tRNA synthetase multienzyme complex);GO:0045892(negative regulation of transcription, DNA-templated);GO:0019901(protein kinase binding);GO:0006469(negative regulation of protein kinase activity);GO:0004860(protein kinase inhibitor activity);GO:0032873(negative regulation of stress-activated MAPK cascade);GO:2001234(negative regulation of apoptotic signaling pathway);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016021(integral component of membrane)","00970(Aminoacyl-tRNA biosynthesis);00970(Aminoacyl-tRNA biosynthesis)","K01886","EC:6.1.1.18","glutaminyl-tRNA synthetase [Source:HGNC Symbol;Acc:HGNC:9751]",{"v":14.7712501682243,"d":"14.77"},{"v":15.0587632355565,"d":"15.06"},{"v":0.980907258927258,"d":"0.98"},{"v":-0.0278113533567483,"d":"-0.03"},{"v":0.99953339282333,"d":"1.00"},1,"down","no"]
["ENSG00000112812","PRSS16","ENST00000485603;ENST00000230582","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0008233(peptidase activity);GO:0006508(proteolysis);GO:0008236(serine-type peptidase activity);GO:0016787(hydrolase activity);GO:0031410(cytoplasmic vesicle);GO:0005764(lysosome);GO:0005768(endosome);GO:0030163(protein catabolic process);GO:0008239(dipeptidyl-peptidase activity);GO:0008239(dipeptidyl-peptidase activity)","NA","NA","NA","protease, serine 16 [Source:HGNC Symbol;Acc:HGNC:9480]",{"v":0.072885347826087,"d":"0.07"},{"v":0.0367543085066163,"d":"0.04"},{"v":1.9830422823209,"d":"1.98"},{"v":0.987715438960788,"d":"0.99"},1,1,"up","no"]
["MSTRG.12671","AL024498.1","ENST00000606522","NA","NA","NA","NA",null,{"v":0.0689552685248131,"d":"0.07"},{"v":0.0339100611828688,"d":"0.03"},{"v":2.03347520232871,"d":"2.03"},{"v":1.02394739763775,"d":"1.02"},1,1,"up","no"]
["ENSG00000165985","C1QL3","ENST00000298943","GO:0005576(extracellular region);GO:0005581(collagen trimer);GO:0050807(regulation of synapse organization)","NA","NA","NA","complement C1q like 3 [Source:HGNC Symbol;Acc:HGNC:19359]",{"v":0.471813,"d":"0.47"},{"v":0.158058,"d":"0.16"},{"v":2.98506244543142,"d":"2.99"},{"v":1.57776111198319,"d":"1.58"},1,1,"up","no"]
["MSTRG.13357","RAET1E-AS1","ENST00000606915;ENST00000446954","NA","NA","NA","NA","RAET1E antisense RNA 1 [Source:NCBI gene;Acc:100652739];RAET1E antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:48994]",{"v":0.0328813855421687,"d":"0.03"},{"v":0.0118079912985274,"d":"0.01"},{"v":2.78467223686635,"d":"2.78"},{"v":1.47750752861559,"d":"1.48"},1,1,"up","no"]
["ENSG00000185269","NOTUM","ENST00000409678","GO:0016787(hydrolase activity);GO:0005576(extracellular region);GO:0016055(Wnt signaling pathway);GO:0052689(carboxylic ester hydrolase activity);GO:0044267(cellular protein metabolic process);GO:0043687(post-translational protein modification);GO:0030178(negative regulation of Wnt signaling pathway);GO:0005788(endoplasmic reticulum lumen);GO:0004629(phospholipase C activity);GO:1990699(palmitoleyl hydrolase activity);GO:0090090(negative regulation of canonical Wnt signaling pathway);GO:1990697(protein depalmitoleylation)","04310(Wnt signaling pathway)","K19882","EC:3.1.1.98","NOTUM, palmitoleoyl-protein carboxylesterase [Source:HGNC Symbol;Acc:HGNC:27106]",{"v":0.00678796654521365,"d":"0.01"},{"v":0.0281084610798278,"d":"0.03"},{"v":0.241491931057196,"d":"0.24"},{"v":-2.04995310962858,"d":"-2.05"},1,1,"down","no"]
["ENSG00000254131","AC093367.1","ENST00000517332","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000007384","RHBDF1","ENST00000262316;ENST00000493647","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0015031(protein transport);GO:0005794(Golgi apparatus);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0006508(proteolysis);GO:0000139(Golgi membrane);GO:0008283(cell proliferation);GO:0016477(cell migration);GO:0061136(regulation of proteasomal protein catabolic process);GO:0019838(growth factor binding);GO:0050708(regulation of protein secretion);GO:0042058(regulation of epidermal growth factor receptor signaling pathway);GO:0050709(negative regulation of protein secretion);GO:0004252(serine-type endopeptidase activity);GO:0016787(hydrolase activity);GO:0008233(peptidase activity);GO:0008233(peptidase activity)","NA","NA","NA","rhomboid 5 homolog 1 [Source:HGNC Symbol;Acc:HGNC:20561]",{"v":0.0442029336589337,"d":"0.04"},{"v":0.0270747382987383,"d":"0.03"},{"v":1.63262644208065,"d":"1.63"},{"v":0.707194728554973,"d":"0.71"},1,1,"up","no"]
["MSTRG.2230","ST5","ENST00000526099;ENST00000526757;ENST00000527870;ENST00000534127;ENST00000530959;ENST00000526062;ENST00000527540;ENST00000533081;ENST00000532738;ENST00000313726;ENST00000527930;ENST00000524513;ENST00000533020;ENST00000532734","GO:0043547(positive regulation of GTPase activity);GO:0005085(guanyl-nucleotide exchange factor activity);GO:0017112(Rab guanyl-nucleotide exchange factor activity);GO:0017112(Rab guanyl-nucleotide exchange factor activity)","NA","NA","NA","suppression of tumorigenicity 5 [Source:HGNC Symbol;Acc:HGNC:11350]",{"v":0.0917656873510027,"d":"0.09"},{"v":0.0232796066470341,"d":"0.02"},{"v":3.94189166261939,"d":"3.94"},{"v":1.9788881264703,"d":"1.98"},1,1,"up","no"]
["ENSG00000204764","RANBP17","ENST00000523727;ENST00000522066;ENST00000521165","GO:0006810(transport);GO:0051028(mRNA transport);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0006886(intracellular protein transport);GO:0015031(protein transport);GO:0005525(GTP binding);GO:0008536(Ran GTPase binding);GO:0005643(nuclear pore);GO:0006611(protein export from nucleus);GO:0005049(nuclear export signal receptor activity);GO:0006606(protein import into nucleus);GO:0005622(intracellular);GO:0005622(intracellular)","NA","NA","NA","RAN binding protein 17 [Source:HGNC Symbol;Acc:HGNC:14428]",{"v":0.00650364541723666,"d":"0.01"},{"v":0.0136433175558596,"d":"0.01"},{"v":0.476690906783405,"d":"0.48"},{"v":-1.06887398964678,"d":"-1.07"},1,1,"down","no"]
["ENSG00000241743","XACT","ENST00000468762","NA","NA","NA","NA","X active specific transcript (non-protein coding) [Source:HGNC Symbol;Acc:HGNC:45056]",0,0,1,0,1,1,"no","no"]
["MSTRG.9445","AC073641.1","ENST00000425192","NA","NA","NA","NA",null,0,{"v":0.058966,"d":"0.06"},"-inf","-inf",1,1,"down","no"]
["ENSG00000164066","INTU","ENST00000503626;ENST00000335251","GO:0005737(cytoplasm);GO:0031514(motile cilium);GO:0005856(cytoskeleton);GO:0042995(cell projection);GO:0005515(protein binding);GO:0007275(multicellular organism development);GO:0007399(nervous system development);GO:0060271(cilium assembly);GO:0030030(cell projection organization);GO:0036064(ciliary basal body);GO:0009986(cell surface);GO:0060173(limb development);GO:0008589(regulation of smoothened signaling pathway);GO:0010839(negative regulation of keratinocyte proliferation);GO:0021513(spinal cord dorsal/ventral patterning);GO:0021915(neural tube development);GO:0030216(keratinocyte differentiation);GO:0030278(regulation of ossification);GO:0031069(hair follicle morphogenesis);GO:0042733(embryonic digit morphogenesis);GO:0044458(motile cilium assembly);GO:0045880(positive regulation of smoothened signaling pathway);GO:0051782(negative regulation of cell division);GO:1905515(non-motile cilium assembly);GO:1905515(non-motile cilium assembly)","NA","NA","NA","inturned planar cell polarity protein [Source:HGNC Symbol;Acc:HGNC:29239]",{"v":0.00760160319930287,"d":"0.01"},{"v":0.0110074574878626,"d":"0.01"},{"v":0.69058665070338,"d":"0.69"},{"v":-0.534105648257855,"d":"-0.53"},1,1,"down","no"]
["ENSG00000198049","AVPR1B","ENST00000367126","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0004930(G-protein coupled receptor activity);GO:0007186(G-protein coupled receptor signaling pathway);GO:0005886(plasma membrane);GO:0004871(signal transducer activity);GO:0007165(signal transduction);GO:0005000(vasopressin receptor activity);GO:0032870(cellular response to hormone stimulus);GO:0005887(integral component of plasma membrane);GO:0007204(positive regulation of cytosolic calcium ion concentration);GO:0042277(peptide binding);GO:1901652(response to peptide);GO:0005768(endosome);GO:0007202(activation of phospholipase C activity);GO:0045907(positive regulation of vasoconstriction);GO:0001992(regulation of systemic arterial blood pressure by vasopressin);GO:0005080(protein kinase C binding)","04020(Calcium signaling pathway);04072(Phospholipase D signaling pathway);04080(Neuroactive ligand-receptor interaction);04270(Vascular smooth muscle contraction)","K04227","NA","arginine vasopressin receptor 1B [Source:HGNC Symbol;Acc:HGNC:896]",{"v":0.0678422164540255,"d":"0.07"},0,"inf","inf",1,1,"up","no"]
["ENSG00000164932","CTHRC1","ENST00000330295;ENST00000415886","GO:0005576(extracellular region);GO:0005581(collagen trimer);GO:0005578(proteinaceous extracellular matrix);GO:0005615(extracellular space);GO:0005109(frizzled binding);GO:0017147(Wnt-protein binding);GO:0016477(cell migration);GO:0032092(positive regulation of protein binding);GO:0033690(positive regulation of osteoblast proliferation);GO:0043932(ossification involved in bone remodeling);GO:0045669(positive regulation of osteoblast differentiation);GO:0060071(Wnt signaling pathway, planar cell polarity pathway);GO:0060122(inner ear receptor stereocilium organization);GO:0090090(negative regulation of canonical Wnt signaling pathway);GO:0090103(cochlea morphogenesis);GO:0090177(establishment of planar polarity involved in neural tube closure);GO:0005737(cytoplasm);GO:0005737(cytoplasm)","NA","NA","NA","collagen triple helix repeat containing 1 [Source:HGNC Symbol;Acc:HGNC:18831]",{"v":0.0249641289414414,"d":"0.02"},{"v":0.038966598536036,"d":"0.04"},{"v":0.640654557475803,"d":"0.64"},{"v":-0.642381433134013,"d":"-0.64"},1,1,"down","no"]
["ENSG00000172288","CDY1","ENST00000361963","GO:0005634(nucleus);GO:0016740(transferase activity);GO:0003824(catalytic activity);GO:0016746(transferase activity, transferring acyl groups);GO:0008152(metabolic process);GO:0004402(histone acetyltransferase activity);GO:0016573(histone acetylation);GO:0007283(spermatogenesis);GO:0035064(methylated histone binding)","NA","NA","NA","chromodomain Y-linked 1 [Source:HGNC Symbol;Acc:HGNC:1809]",{"v":0.009693248,"d":"0.01"},0,"inf","inf",1,1,"up","no"]
["MSTRG.6867","AC060780.2","ENST00000589047","NA","NA","NA","NA",null,{"v":1.500524,"d":"1.50"},{"v":0.230424,"d":"0.23"},{"v":6.51201263757248,"d":"6.51"},{"v":2.7031034993808,"d":"2.70"},1,1,"up","no"]
["ENSG00000138115","CYP2C8","ENST00000527953","GO:0055114(oxidation-reduction process);GO:0005506(iron ion binding);GO:0016705(oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen);GO:0020037(heme binding);GO:0016020(membrane);GO:0046872(metal ion binding);GO:0004497(monooxygenase activity);GO:0016491(oxidoreductase activity);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0008392(arachidonic acid epoxygenase activity);GO:0019373(epoxygenase P450 pathway);GO:0070330(aromatase activity);GO:0043231(intracellular membrane-bounded organelle);GO:0006805(xenobiotic metabolic process);GO:0031090(organelle membrane);GO:0019825(oxygen binding);GO:0101020(estrogen 16-alpha-hydroxylase activity);GO:0002933(lipid hydroxylation);GO:0008202(steroid metabolic process);GO:0017144(drug metabolic process);GO:0097267(omega-hydroxylase P450 pathway);GO:0034875(caffeine oxidase activity);GO:0042738(exogenous drug catabolic process);GO:0070989(oxidative demethylation);GO:0006082(organic acid metabolic process)","00590(Arachidonic acid metabolism);00591(Linoleic acid metabolism);00830(Retinol metabolism);00982(Drug metabolism - cytochrome P450);04726(Serotonergic synapse);05204(Chemical carcinogenesis)","NA","NA","cytochrome P450 family 2 subfamily C member 8 [Source:HGNC Symbol;Acc:HGNC:2622]",{"v":0.0138152570984053,"d":"0.01"},{"v":0.0234945005834306,"d":"0.02"},{"v":0.588020888094487,"d":"0.59"},{"v":-0.766060690480345,"d":"-0.77"},1,1,"down","no"]
["ENSG00000164438","TLX3","ENST00000296921","GO:0005634(nucleus);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0043565(sequence-specific DNA binding);GO:0005515(protein binding);GO:0007275(multicellular organism development);GO:0001708(cell fate specification);GO:0001764(neuron migration);GO:0002087(regulation of respiratory gaseous exchange by neurological system process);GO:0007417(central nervous system development);GO:0007585(respiratory gaseous exchange);GO:0030182(neuron differentiation);GO:0045665(negative regulation of neuron differentiation);GO:0048665(neuron fate specification)","05202(Transcriptional misregulation in cancers)","K15607","NA","T-cell leukemia homeobox 3 [Source:HGNC Symbol;Acc:HGNC:13532]",0,{"v":0.030559,"d":"0.03"},"-inf","-inf",1,1,"down","no"]
["ENSG00000101883","RHOXF1","ENST00000217999","GO:0005634(nucleus);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0043565(sequence-specific DNA binding);GO:0007275(multicellular organism development);GO:0010628(positive regulation of gene expression);GO:0030518(intracellular steroid hormone receptor signaling pathway);GO:0019953(sexual reproduction);GO:0007276(gamete generation)","NA","NA","NA","Rhox homeobox family member 1 [Source:HGNC Symbol;Acc:HGNC:29993]",{"v":0.06726,"d":"0.07"},0,"inf","inf",1,1,"up","no"]
["ENSG00000161807","OR7G1","ENST00000541538","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0004930(G-protein coupled receptor activity);GO:0007186(G-protein coupled receptor signaling pathway);GO:0005886(plasma membrane);GO:0004871(signal transducer activity);GO:0007165(signal transduction);GO:0004984(olfactory receptor activity);GO:0007608(sensory perception of smell);GO:0050896(response to stimulus);GO:0050911(detection of chemical stimulus involved in sensory perception of smell)","04740(Olfactory transduction)","K04257","NA","olfactory receptor family 7 subfamily G member 1 [Source:HGNC Symbol;Acc:HGNC:8465]",{"v":0.054917,"d":"0.05"},{"v":0.047606,"d":"0.05"},{"v":1.15357307902365,"d":"1.15"},{"v":0.206109401858277,"d":"0.21"},1,1,"up","no"]
["ENSG00000214248","AC010336.1","ENST00000539278","NA","NA","NA","NA",null,{"v":0.118156,"d":"0.12"},{"v":7.541E-3,"d":"0.01"},{"v":15.6684789815674,"d":"15.67"},{"v":3.96979323179706,"d":"3.97"},1,1,"up","no"]
["MSTRG.7763","ANGPTL4","ENST00000301455","GO:0051005(negative regulation of lipoprotein lipase activity);GO:0005615(extracellular space);GO:0043066(negative regulation of apoptotic process);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0007275(multicellular organism development);GO:0005578(proteinaceous extracellular matrix);GO:0001525(angiogenesis);GO:0030154(cell differentiation);GO:0042802(identical protein binding);GO:0072562(blood microparticle);GO:0001666(response to hypoxia);GO:0045766(positive regulation of angiogenesis);GO:0004857(enzyme inhibitor activity);GO:0019216(regulation of lipid metabolic process);GO:0070328(triglyceride homeostasis);GO:0051260(protein homooligomerization);GO:2000352(negative regulation of endothelial cell apoptotic process)","03320(PPAR signaling pathway);04979(Cholesterol metabolism)","K08767","NA","angiopoietin like 4 [Source:HGNC Symbol;Acc:HGNC:16039]",{"v":0.0768164270749396,"d":"0.08"},{"v":0.0324290265914585,"d":"0.03"},{"v":2.36875525259128,"d":"2.37"},{"v":1.24412914238832,"d":"1.24"},1,1,"up","no"]
["MSTRG.7705","FUT3","ENST00000303225","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016740(transferase activity);GO:0016757(transferase activity, transferring glycosyl groups);GO:0006486(protein glycosylation);GO:0005794(Golgi apparatus);GO:0032580(Golgi cisterna membrane);GO:0070062(extracellular exosome);GO:0036065(fucosylation);GO:0008417(fucosyltransferase activity);GO:0000139(Golgi membrane);GO:0017060(3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity);GO:0046920(alpha-(1->3)-fucosyltransferase activity);GO:0006672(ceramide metabolic process);GO:0009312(oligosaccharide biosynthetic process);GO:0009988(cell-cell recognition);GO:0043413(macromolecule glycosylation)","00601(Glycosphingolipid biosynthesis - lacto and neolacto series)","K00716","EC:2.4.1.65","fucosyltransferase 3 (Lewis blood group) [Source:HGNC Symbol;Acc:HGNC:4014]",{"v":0.0617708150530717,"d":"0.06"},0,"inf","inf",1,1,"up","no"]
["ENSG00000158220","ESYT3","ENST00000460133;ENST00000389567","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0046872(metal ion binding);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0008289(lipid binding);GO:0006869(lipid transport);GO:0006687(glycosphingolipid metabolic process);GO:0005887(integral component of plasma membrane);GO:0031227(intrinsic component of endoplasmic reticulum membrane);GO:0031234(extrinsic component of cytoplasmic side of plasma membrane);GO:0044232(organelle membrane contact site);GO:0044232(organelle membrane contact site)","NA","NA","NA","extended synaptotagmin 3 [Source:HGNC Symbol;Acc:HGNC:24295]",{"v":0.0223717206601467,"d":"0.02"},{"v":0.0126490238386308,"d":"0.01"},{"v":1.7686519486051,"d":"1.77"},{"v":0.822650169325596,"d":"0.82"},1,1,"up","no"]
["ENSG00000225530","SP3P","ENST00000414049","NA","NA","NA","NA","Sp3 transcription factor pseudogene [Source:HGNC Symbol;Acc:HGNC:35430]",{"v":0.024892,"d":"0.02"},0,"inf","inf",1,1,"up","no"]
["ENSG00000268804","LINC02132","ENST00000598933","NA","NA","NA","NA","long intergenic non-protein coding RNA 2132 [Source:HGNC Symbol;Acc:HGNC:52992]",{"v":0.20538,"d":"0.21"},{"v":0.093073,"d":"0.09"},{"v":2.20665499124343,"d":"2.21"},{"v":1.14186108302444,"d":"1.14"},1,1,"up","no"]
["ENSG00000159527","PGLYRP3","ENST00000290722","GO:0016020(membrane);GO:0008270(zinc ion binding);GO:0005576(extracellular region);GO:0002376(immune system process);GO:0045087(innate immune response);GO:0042742(defense response to bacterium);GO:0005622(intracellular);GO:0002221(pattern recognition receptor signaling pathway);GO:0043234(protein complex);GO:0050830(defense response to Gram-positive bacterium);GO:0061844(antimicrobial humoral immune response mediated by antimicrobial peptide);GO:0009253(peptidoglycan catabolic process);GO:0019730(antimicrobial humoral response);GO:0046982(protein heterodimerization activity);GO:0031640(killing of cells of other organism);GO:0042834(peptidoglycan binding);GO:0008745(N-acetylmuramoyl-L-alanine amidase activity);GO:0016019(peptidoglycan receptor activity);GO:0016045(detection of bacterium);GO:0051714(positive regulation of cytolysis in other organism);GO:0032689(negative regulation of interferon-gamma production);GO:0032827(negative regulation of natural killer cell differentiation involved in immune response);GO:0044117(growth of symbiont in host)","NA","NA","NA","peptidoglycan recognition protein 3 [Source:HGNC Symbol;Acc:HGNC:30014]",{"v":0.008764,"d":"0.01"},{"v":0.007909,"d":"0.01"},{"v":1.10810469085852,"d":"1.11"},{"v":0.148094189913627,"d":"0.15"},1,1,"up","no"]
["ENSG00000250896","RNPS1P1","ENST00000507437","NA","NA","NA","NA","RNA binding protein with serine rich domain 1 pseudogene 1 [Source:HGNC Symbol;Acc:HGNC:39525]",0,{"v":1.658813,"d":"1.66"},"-inf","-inf",1,1,"down","no"]
["MSTRG.10087","COL18A1-AS1","ENST00000397787","NA","NA","NA","NA","COL18A1 antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:23132]",{"v":0.013928994211288,"d":"0.01"},{"v":0.00767477568740955,"d":"0.01"},{"v":1.81490570911909,"d":"1.81"},{"v":0.859894596970378,"d":"0.86"},1,1,"up","no"]
["ENSG00000165023","DIRAS2","ENST00000375765","GO:0016020(membrane);GO:0005525(GTP binding);GO:0000166(nucleotide binding);GO:0007165(signal transduction);GO:0003924(GTPase activity);GO:0005886(plasma membrane)","NA","NA","NA","DIRAS family GTPase 2 [Source:HGNC Symbol;Acc:HGNC:19323]",{"v":0.0209519014084507,"d":"0.02"},{"v":0.00973605889884763,"d":"0.01"},{"v":2.15199000192271,"d":"2.15"},{"v":1.10567137519471,"d":"1.11"},1,1,"up","no"]
["ENSG00000243417","AC023424.2","ENST00000493479","NA","NA","NA","NA",null,0,{"v":0.042081,"d":"0.04"},"-inf","-inf",1,1,"down","no"]
["ENSG00000115641","FHL2","ENST00000452732;ENST00000607522;ENST00000409177;ENST00000409807;ENST00000393353;ENST00000322142;ENST00000408995","GO:0046872(metal ion binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0005515(protein binding);GO:0003713(transcription coactivator activity);GO:0045893(positive regulation of transcription, DNA-templated);GO:0005925(focal adhesion);GO:0042802(identical protein binding);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0005654(nucleoplasm);GO:0043066(negative regulation of apoptotic process);GO:0008134(transcription factor binding);GO:0030521(androgen receptor signaling pathway);GO:0019216(regulation of lipid metabolic process);GO:0050681(androgen receptor binding);GO:0009725(response to hormone);GO:0001649(osteoblast differentiation);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0045892(negative regulation of transcription, DNA-templated);GO:0055014(atrial cardiac muscle cell development);GO:0055015(ventricular cardiac muscle cell development);GO:0060347(heart trabecula formation);GO:0030018(Z disc);GO:0031430(M band);GO:0031430(M band)","04380(Osteoclast differentiation);04380(Osteoclast differentiation)","K14380","NA","four and a half LIM domains 2 [Source:HGNC Symbol;Acc:HGNC:3703]",{"v":0.0541481305463326,"d":"0.05"},{"v":0.197902381980078,"d":"0.20"},{"v":0.273610302233671,"d":"0.27"},{"v":-1.86980554192376,"d":"-1.87"},1,1,"down","no"]
["ENSG00000093009","CDC45","ENST00000471470;ENST00000407835;ENST00000455750","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0032508(DNA duplex unwinding);GO:0005813(centrosome);GO:0005515(protein binding);GO:0006270(DNA replication initiation);GO:0007049(cell cycle);GO:0006260(DNA replication);GO:0003682(chromatin binding);GO:0005654(nucleoplasm);GO:0003697(single-stranded DNA binding);GO:0000082(G1/S transition of mitotic cell cycle);GO:0000727(double-strand break repair via break-induced replication);GO:0003688(DNA replication origin binding);GO:0043138(3'-5' DNA helicase activity);GO:0000076(DNA replication checkpoint);GO:0000083(regulation of transcription involved in G1/S transition of mitotic cell cycle);GO:0006267(pre-replicative complex assembly involved in nuclear cell cycle DNA replication);GO:0031938(regulation of chromatin silencing at telomere);GO:1900087(positive regulation of G1/S transition of mitotic cell cycle);GO:1902977(mitotic DNA replication preinitiation complex assembly);GO:0005656(nuclear pre-replicative complex);GO:0031261(DNA replication preinitiation complex);GO:0031298(replication fork protection complex);GO:0031298(replication fork protection complex)","04110(Cell cycle);04110(Cell cycle)","K06628","NA","cell division cycle 45 [Source:HGNC Symbol;Acc:HGNC:1739]",{"v":0.322407600843289,"d":"0.32"},{"v":0.140148599789178,"d":"0.14"},{"v":2.30046965384084,"d":"2.30"},{"v":1.20192842556001,"d":"1.20"},1,1,"up","no"]
["ENSG00000280018","CU634019.6","ENST00000624728;ENST00000623165","NA","NA","NA","NA",null,{"v":0.0565053579418345,"d":"0.06"},{"v":0.0627209653243848,"d":"0.06"},{"v":0.900900642226981,"d":"0.90"},{"v":-0.150560090813656,"d":"-0.15"},1,1,"down","no"]
["MSTRG.5532","CASKIN1","ENST00000343516","GO:0005737(cytoplasm);GO:0005515(protein binding);GO:0007165(signal transduction);GO:0016020(membrane)","NA","NA","NA","CASK interacting protein 1 [Source:HGNC Symbol;Acc:HGNC:20879]",{"v":0.0836223620309051,"d":"0.08"},{"v":0.0232511434878587,"d":"0.02"},{"v":3.59648384925976,"d":"3.60"},{"v":1.84658712540463,"d":"1.85"},1,1,"up","no"]
["ENSG00000124215","CDH26","ENST00000370991;ENST00000348616;ENST00000497614;ENST00000477058","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0046872(metal ion binding);GO:0005509(calcium ion binding);GO:0007155(cell adhesion);GO:0007156(homophilic cell adhesion via plasma membrane adhesion molecules);GO:0005886(plasma membrane);GO:0005886(plasma membrane)","NA","NA","NA","cadherin 26 [Source:HGNC Symbol;Acc:HGNC:15902]",{"v":0.0694052353862213,"d":"0.07"},{"v":0.164476959986082,"d":"0.16"},{"v":0.421975426783753,"d":"0.42"},{"v":-1.24476910706732,"d":"-1.24"},1,1,"down","no"]
["ENSG00000168852","TPTE2P5","ENST00000458118;ENST00000633547;ENST00000432905","NA","NA","NA","NA","transmembrane phosphoinositide 3-phosphatase and tensin homolog 2 pseudogene 5 [Source:HGNC Symbol;Acc:HGNC:42356]",{"v":0.208979209095661,"d":"0.21"},0,"inf","inf",1,1,"up","no"]
["ENSG00000231637","USP17L29","ENST00000511681","GO:0003723(RNA binding);GO:0005634(nucleus);GO:0016579(protein deubiquitination);GO:0016787(hydrolase activity);GO:0005783(endoplasmic reticulum);GO:0008233(peptidase activity);GO:0008234(cysteine-type peptidase activity);GO:0006508(proteolysis);GO:0006511(ubiquitin-dependent protein catabolic process);GO:0006915(apoptotic process);GO:0036459(thiol-dependent ubiquitinyl hydrolase activity);GO:0005730(nucleolus);GO:0004843(thiol-dependent ubiquitin-specific protease activity);GO:0005540(hyaluronic acid binding);GO:0071947(protein deubiquitination involved in ubiquitin-dependent protein catabolic process);GO:1904037(positive regulation of epithelial cell apoptotic process)","NA","NA","NA","ubiquitin specific peptidase 17-like family member 29 [Source:HGNC Symbol;Acc:HGNC:44457]",{"v":0.00968,"d":"0.01"},{"v":1.591E-3,"d":"0.00"},{"v":6.08422375864236,"d":"6.08"},{"v":2.60507321183091,"d":"2.61"},1,1,"up","no"]
["ENSG00000181234","TMEM132C","ENST00000435159","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0003674(molecular_function);GO:0008150(biological_process);GO:0005575(cellular_component)","NA","NA","NA","transmembrane protein 132C [Source:HGNC Symbol;Acc:HGNC:25436]",{"v":0.094608,"d":"0.09"},{"v":0.034546,"d":"0.03"},{"v":2.73860939037805,"d":"2.74"},{"v":1.45344350819336,"d":"1.45"},1,1,"up","no"]
["ENSG00000165807","PPP1R36","ENST00000298705","GO:0004864(protein phosphatase inhibitor activity);GO:0019902(phosphatase binding);GO:0010923(negative regulation of phosphatase activity)","NA","NA","NA","protein phosphatase 1 regulatory subunit 36 [Source:HGNC Symbol;Acc:HGNC:20097]",0,{"v":0.00881838506304559,"d":"0.01"},"-inf","-inf",1,1,"down","no"]
["ENSG00000235957","COX7CP1","ENST00000446556","NA","NA","NA","NA","cytochrome c oxidase subunit 7C pseudogene 1 [Source:HGNC Symbol;Acc:HGNC:2293]",0,0,1,0,1,1,"no","no"]
["ENSG00000223427","AC016716.1","ENST00000265882","NA","NA","NA","NA",null,0,{"v":0.062722,"d":"0.06"},"-inf","-inf",1,1,"down","no"]
["MSTRG.710","SNORA66","ENST00000384792","NA","NA","NA","NA","small nucleolar RNA, H/ACA box 66 [Source:HGNC Symbol;Acc:HGNC:10223]",{"v":0.885838,"d":"0.89"},0,"inf","inf",1,1,"up","no"]
["MSTRG.9058","AC012442.1","ENST00000436885","NA","NA","NA","NA",null,0,{"v":0.172491,"d":"0.17"},"-inf","-inf",1,1,"down","no"]
["ENSG00000162896","PIGR","ENST00000356495","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005886(plasma membrane);GO:0005576(extracellular region);GO:0005615(extracellular space);GO:0070062(extracellular exosome);GO:0001895(retina homeostasis);GO:0005887(integral component of plasma membrane);GO:0043312(neutrophil degranulation);GO:0007173(epidermal growth factor receptor signaling pathway);GO:0035577(azurophil granule membrane);GO:0043113(receptor clustering);GO:0043235(receptor complex);GO:0001580(detection of chemical stimulus involved in sensory perception of bitter taste);GO:0001792(polymeric immunoglobulin receptor activity);GO:0002415(immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor);GO:0038093(Fc receptor signaling pathway)","04672(Intestinal immune network for IgA production)","K13073","NA","polymeric immunoglobulin receptor [Source:HGNC Symbol;Acc:HGNC:8968]",{"v":0.0350836930987203,"d":"0.04"},{"v":0.0356879942870201,"d":"0.04"},{"v":0.983067101405595,"d":"0.98"},{"v":-0.0246382006397859,"d":"-0.02"},1,1,"down","no"]
["MSTRG.1232","AL353708.3","ENST00000610272","NA","NA","NA","NA",null,{"v":0.095758,"d":"0.10"},{"v":0.659678,"d":"0.66"},{"v":0.14515869863782,"d":"0.15"},{"v":-2.78429706680412,"d":"-2.78"},1,1,"down","no"]
["ENSG00000187391","MAGI2","ENST00000354212;ENST00000637249","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0007165(signal transduction);GO:0005886(plasma membrane);GO:0032947(protein complex scaffold);GO:0005515(protein binding);GO:0048471(perinuclear region of cytoplasm);GO:0030054(cell junction);GO:0045202(synapse);GO:0007399(nervous system development);GO:0030425(dendrite);GO:0005923(bicellular tight junction);GO:0005768(endosome);GO:0051291(protein heterooligomerization);GO:0008285(negative regulation of cell proliferation);GO:0043234(protein complex);GO:0014069(postsynaptic density);GO:0005770(late endosome);GO:0019902(phosphatase binding);GO:0043005(neuron projection);GO:0060395(SMAD protein signal transduction);GO:0043113(receptor clustering);GO:0072015(glomerular visceral epithelial cell development);GO:0036057(slit diaphragm);GO:0051898(negative regulation of protein kinase B signaling);GO:0030336(negative regulation of cell migration);GO:0010976(positive regulation of neuron projection development);GO:0030159(receptor signaling complex scaffold activity);GO:0046332(SMAD binding);GO:0032926(negative regulation of activin receptor signaling pathway);GO:0038180(nerve growth factor signaling pathway);GO:1990090(cellular response to nerve growth factor stimulus);GO:0032516(positive regulation of phosphoprotein phosphatase activity);GO:0002092(positive regulation of receptor internalization);GO:0071850(mitotic cell cycle arrest);GO:0004871(signal transducer activity);GO:0031697(beta-1 adrenergic receptor binding);GO:0070699(type II activin receptor binding);GO:0003402(planar cell polarity pathway involved in axis elongation);GO:0097118(neuroligin clustering involved in postsynaptic membrane assembly);GO:2000809(positive regulation of synaptic vesicle clustering);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0016310(phosphorylation)","04015(Rap1 signaling pathway);04015(Rap1 signaling pathway)","K05629","NA","membrane associated guanylate kinase, WW and PDZ domain containing 2 [Source:HGNC Symbol;Acc:HGNC:18957]",{"v":0.00408252465983698,"d":"0.00"},{"v":0.00837435903453963,"d":"0.01"},{"v":0.487502941180192,"d":"0.49"},{"v":-1.03651717199788,"d":"-1.04"},1,1,"down","no"]
["ENSG00000249592","AC139887.2","ENST00000503571;ENST00000503405;ENST00000503185;ENST00000507446","NA","NA","NA","NA",null,{"v":0.557607334603175,"d":"0.56"},{"v":0.335465386666667,"d":"0.34"},{"v":1.66219036826365,"d":"1.66"},{"v":0.733085621351373,"d":"0.73"},1,1,"up","no"]
["MSTRG.10306","IGLC6","ENST00000410078","NA","NA","NA","NA","immunoglobulin lambda constant 6 (gene/pseudogene) [Source:HGNC Symbol;Acc:HGNC:5860]",{"v":0.313493,"d":"0.31"},0,"inf","inf",1,1,"up","no"]
["ENSG00000144451","SPAG16","ENST00000406979;ENST00000413312;ENST00000272898;ENST00000452556;ENST00000432529","GO:0005737(cytoplasm);GO:0031514(motile cilium);GO:0005856(cytoskeleton);GO:0042995(cell projection);GO:0060271(cilium assembly);GO:0005929(cilium);GO:0030030(cell projection organization);GO:0005930(axoneme);GO:0035082(axoneme assembly);GO:0007288(sperm axoneme assembly);GO:0051012(microtubule sliding);GO:0060294(cilium movement involved in cell motility);GO:0097231(cell motility in response to calcium ion);GO:0005634(nucleus);GO:1990716(axonemal central apparatus);GO:1990716(axonemal central apparatus)","NA","NA","NA","sperm associated antigen 16 [Source:HGNC Symbol;Acc:HGNC:23225]",{"v":0.0972004768075572,"d":"0.10"},{"v":0.0995003400750878,"d":"0.10"},{"v":0.976885875306607,"d":"0.98"},{"v":-0.0337380656991035,"d":"-0.03"},1,1,"down","no"]
["ENSG00000264575","LINC00526","ENST00000581067","NA","NA","NA","NA","long intergenic non-protein coding RNA 526 [Source:HGNC Symbol;Acc:HGNC:28278]",{"v":0.218402,"d":"0.22"},{"v":0.329622,"d":"0.33"},{"v":0.662583201363987,"d":"0.66"},{"v":-0.593826468009469,"d":"-0.59"},1,1,"down","no"]
["MSTRG.14654","RPL12P25","ENST00000598100","NA","NA","NA","NA","ribosomal protein L12 pseudogene 25 [Source:HGNC Symbol;Acc:HGNC:37008]",0,0,1,0,1,1,"no","no"]
["ENSG00000228215","AL954650.1","ENST00000430776","NA","NA","NA","NA",null,{"v":0.084709,"d":"0.08"},{"v":0.25574,"d":"0.26"},{"v":0.331230937671072,"d":"0.33"},{"v":-1.59409066498451,"d":"-1.59"},1,1,"down","no"]
["ENSG00000160097","FNDC5","ENST00000373471","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0014850(response to muscle activity);GO:0090336(positive regulation of brown fat cell differentiation);GO:0005576(extracellular region);GO:0005783(endoplasmic reticulum);GO:0005886(plasma membrane);GO:0005179(hormone activity);GO:0005777(peroxisome);GO:0005778(peroxisomal membrane);GO:0003674(molecular_function);GO:0008150(biological_process)","NA","NA","NA","fibronectin type III domain containing 5 [Source:HGNC Symbol;Acc:HGNC:20240]",{"v":0.0230118126791972,"d":"0.02"},{"v":0.0258848079006053,"d":"0.03"},{"v":0.889008439527924,"d":"0.89"},{"v":-0.169730979986096,"d":"-0.17"},1,1,"down","no"]
["ENSG00000197241","SLC2A7","ENST00000400906","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005215(transporter activity);GO:0055085(transmembrane transport);GO:0022857(transmembrane transporter activity);GO:0022891(substrate-specific transmembrane transporter activity);GO:0008643(carbohydrate transport);GO:0005886(plasma membrane);GO:0008645(hexose transport);GO:0051119(sugar transmembrane transporter activity);GO:0034219(carbohydrate transmembrane transport)","NA","NA","NA","solute carrier family 2 member 7 [Source:HGNC Symbol;Acc:HGNC:13445]",{"v":0.019494,"d":"0.02"},0,"inf","inf",1,1,"up","no"]
["ENSG00000261645","DISC1FP1","ENST00000562245;ENST00000561596","NA","NA","NA","NA","DISC1 fusion partner 1 (non-protein coding) [Source:HGNC Symbol;Acc:HGNC:33625]",0,0,1,0,1,1,"no","no"]
["MSTRG.1376","DTL","ENST00000542077;ENST00000463791;ENST00000366991","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005730(nucleolus);GO:0005829(cytosol);GO:0016567(protein ubiquitination);GO:0005694(chromosome);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0006974(cellular response to DNA damage stimulus);GO:0006511(ubiquitin-dependent protein catabolic process);GO:0006260(DNA replication);GO:0005813(centrosome);GO:0005815(microtubule organizing center);GO:0005654(nucleoplasm);GO:0043687(post-translational protein modification);GO:0031965(nuclear membrane);GO:0004842(ubiquitin-protein transferase activity);GO:0009411(response to UV);GO:0051726(regulation of cell cycle);GO:0031572(G2 DNA damage checkpoint);GO:0000209(protein polyubiquitination);GO:0006513(protein monoubiquitination);GO:0042769(DNA damage response, detection of DNA damage);GO:0019985(translesion synthesis);GO:0031464(Cul4A-RING E3 ubiquitin ligase complex);GO:0031465(Cul4B-RING E3 ubiquitin ligase complex);GO:0031465(Cul4B-RING E3 ubiquitin ligase complex)","NA","NA","NA","denticleless E3 ubiquitin protein ligase homolog [Source:HGNC Symbol;Acc:HGNC:30288]",{"v":0.0916650469894223,"d":"0.09"},{"v":0.141778813873068,"d":"0.14"},{"v":0.646535575276348,"d":"0.65"},{"v":-0.629198339140009,"d":"-0.63"},1,1,"down","no"]
["ENSG00000251431","AC245884.7","ENST00000514037","NA","NA","NA","NA",null,{"v":0.039436,"d":"0.04"},0,"inf","inf",1,1,"up","no"]
["ENSG00000171004","HS6ST2","ENST00000370836","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005654(nucleoplasm);GO:0016740(transferase activity);GO:0008146(sulfotransferase activity);GO:0070062(extracellular exosome);GO:0000139(Golgi membrane);GO:0006024(glycosaminoglycan biosynthetic process);GO:0017095(heparan sulfate 6-O-sulfotransferase activity);GO:0015015(heparan sulfate proteoglycan biosynthetic process, enzymatic modification)","00534(Glycosaminoglycan biosynthesis - heparan sulfate / heparin)","K08102","EC:2.8.2.-","heparan sulfate 6-O-sulfotransferase 2 [Source:HGNC Symbol;Acc:HGNC:19133]",0,{"v":0.0637570273890444,"d":"0.06"},"-inf","-inf",1,1,"down","no"]
["MSTRG.15270","AC115618.1","ENST00000376775","NA","NA","NA","NA",null,{"v":0.280885,"d":"0.28"},{"v":0.284214,"d":"0.28"},{"v":0.988286995010802,"d":"0.99"},{"v":-0.0169980387512521,"d":"-0.02"},1,1,"down","no"]
["ENSG00000279320","AC069528.2","ENST00000624849","NA","NA","NA","NA",null,{"v":0.051634,"d":"0.05"},{"v":0.065613,"d":"0.07"},{"v":0.78694770853337,"d":"0.79"},{"v":-0.345660320839467,"d":"-0.35"},1,1,"down","no"]
["ENSG00000273840","AF254983.1","ENST00000612267","NA","NA","NA","NA",null,{"v":0.011995,"d":"0.01"},{"v":0.007841,"d":"0.01"},{"v":1.52977936487693,"d":"1.53"},{"v":0.613323592688418,"d":"0.61"},1,1,"up","no"]
["ENSG00000171914","TLN2","ENST00000561311","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0003779(actin binding);GO:0051015(actin filament binding);GO:0007155(cell adhesion);GO:0005886(plasma membrane);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0005200(structural constituent of cytoskeleton);GO:0030054(cell junction);GO:0045202(synapse);GO:0005925(focal adhesion);GO:0007016(cytoskeletal anchoring at plasma membrane);GO:0007043(cell-cell junction assembly);GO:0005911(cell-cell junction);GO:0015629(actin cytoskeleton);GO:0005198(structural molecule activity);GO:0001726(ruffle)","04015(Rap1 signaling pathway);04510(Focal adhesion);04611(Platelet activation);05166(HTLV-I infection)","K06271","NA","talin 2 [Source:HGNC Symbol;Acc:HGNC:15447]",{"v":0.0342005330372016,"d":"0.03"},{"v":0.0370626096612993,"d":"0.04"},{"v":0.922777250435058,"d":"0.92"},{"v":-0.11594565771637,"d":"-0.12"},1,1,"down","no"]
["ENSG00000224977","AL121983.1","ENST00000424181","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000228127","LINC01649","ENST00000438885;ENST00000634255","NA","NA","NA","NA","long intergenic non-protein coding RNA 1649 [Source:HGNC Symbol;Acc:HGNC:52436]",{"v":0.0825447022532189,"d":"0.08"},{"v":0.0330202918454936,"d":"0.03"},{"v":2.49981746495327,"d":"2.50"},{"v":1.32182275407895,"d":"1.32"},1,1,"up","no"]
["ENSG00000255474","AC005833.2","ENST00000527518","NA","NA","NA","NA",null,{"v":0.084778,"d":"0.08"},{"v":0.030843,"d":"0.03"},{"v":2.74869500372856,"d":"2.75"},{"v":1.45874683372624,"d":"1.46"},1,1,"up","no"]
["ENSG00000178722","C5orf64","ENST00000505642","NA","NA","NA","NA","chromosome 5 open reading frame 64 [Source:HGNC Symbol;Acc:HGNC:26744]",{"v":0.012713774424932,"d":"0.01"},0,"inf","inf",1,1,"up","no"]
["ENSG00000080618","CPB2","ENST00000181383","GO:0005623(cell);GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0016787(hydrolase activity);GO:0008233(peptidase activity);GO:0006508(proteolysis);GO:0005576(extracellular region);GO:0004181(metallocarboxypeptidase activity);GO:0004180(carboxypeptidase activity);GO:0008237(metallopeptidase activity);GO:0005615(extracellular space);GO:0030449(regulation of complement activation);GO:0070062(extracellular exosome);GO:0007596(blood coagulation);GO:0007599(hemostasis);GO:0042730(fibrinolysis);GO:0003331(positive regulation of extracellular matrix constituent secretion);GO:0009408(response to heat);GO:0010757(negative regulation of plasminogen activation);GO:0042493(response to drug);GO:0051918(negative regulation of fibrinolysis);GO:0071333(cellular response to glucose stimulus);GO:0097421(liver regeneration);GO:2000346(negative regulation of hepatocyte proliferation)","04610(Complement and coagulation cascades);04972(Pancreatic secretion);04974(Protein digestion and absorption)","K01300","EC:3.4.17.20","carboxypeptidase B2 [Source:HGNC Symbol;Acc:HGNC:2300]",{"v":0.0268782891907187,"d":"0.03"},0,"inf","inf",1,1,"up","no"]
["ENSG00000237263","MAPK6PS3","ENST00000403865","NA","NA","NA","NA","mitogen-activated protein kinase 6 pseudogene 3 [Source:HGNC Symbol;Acc:HGNC:18977]",0,{"v":0.021103,"d":"0.02"},"-inf","-inf",1,1,"down","no"]
["ENSG00000268964","ERVV-2","ENST00000601417","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0019031(viral envelope)","NA","NA","NA","endogenous retrovirus group V member 2, envelope [Source:HGNC Symbol;Acc:HGNC:39051]",0,{"v":0.00807,"d":"0.01"},"-inf","-inf",1,1,"down","no"]
["ENSG00000104808","DHDH","ENST00000520557;ENST00000221403","GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0005975(carbohydrate metabolic process);GO:0009055(electron carrier activity);GO:0047115(trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity);GO:0008746(NAD(P)+ transhydrogenase activity);GO:0047837(D-xylose 1-dehydrogenase (NADP+) activity);GO:0042843(D-xylose catabolic process);GO:0042843(D-xylose catabolic process)","00040(Pentose and glucuronate interconversions);00980(Metabolism of xenobiotics by cytochrome P450);00980(Metabolism of xenobiotics by cytochrome P450)","K00078","EC:1.3.1.20;EC:1.1.1.179","dihydrodiol dehydrogenase [Source:HGNC Symbol;Acc:HGNC:17887]",{"v":0.114925,"d":"0.11"},{"v":0.038419,"d":"0.04"},{"v":2.99135844243734,"d":"2.99"},{"v":1.58080079315307,"d":"1.58"},1,1,"up","no"]
["ENSG00000176920","FUT2","ENST00000425340","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016740(transferase activity);GO:0016757(transferase activity, transferring glycosyl groups);GO:0005794(Golgi apparatus);GO:0005975(carbohydrate metabolic process);GO:0006486(protein glycosylation);GO:0032580(Golgi cisterna membrane);GO:0008107(galactoside 2-alpha-L-fucosyltransferase activity);GO:0036065(fucosylation);GO:0070062(extracellular exosome);GO:0008417(fucosyltransferase activity);GO:0042355(L-fucose catabolic process)","00601(Glycosphingolipid biosynthesis - lacto and neolacto series);00603(Glycosphingolipid biosynthesis - globo and isoglobo series)","K00718","EC:2.4.1.69","fucosyltransferase 2 [Source:HGNC Symbol;Acc:HGNC:4013]",{"v":0.138350219822485,"d":"0.14"},{"v":0.0539482375739645,"d":"0.05"},{"v":2.56449934314913,"d":"2.56"},{"v":1.35867720179462,"d":"1.36"},1,1,"up","no"]
["ENSG00000267279","AC090409.1","ENST00000586949;ENST00000587754","NA","NA","NA","NA",null,{"v":0.359614443703086,"d":"0.36"},{"v":0.523843788990826,"d":"0.52"},{"v":0.686491758155376,"d":"0.69"},{"v":-0.542685695039012,"d":"-0.54"},1,1,"down","no"]
["ENSG00000253182","AC084026.1","ENST00000522028","NA","NA","NA","NA",null,{"v":0.027949,"d":"0.03"},0,"inf","inf",1,1,"up","no"]
["ENSG00000172236","TPSAB1","ENST00000561736;ENST00000461509;ENST00000562432","GO:0005615(extracellular space);GO:0016787(hydrolase activity);GO:0005515(protein binding);GO:0008233(peptidase activity);GO:0006508(proteolysis);GO:0005576(extracellular region);GO:0004252(serine-type endopeptidase activity);GO:0008236(serine-type peptidase activity);GO:0031012(extracellular matrix);GO:0006952(defense response);GO:0022617(extracellular matrix disassembly);GO:0022617(extracellular matrix disassembly)","NA","NA","NA","tryptase alpha/beta 1 [Source:HGNC Symbol;Acc:HGNC:12019]",{"v":0.561048169973545,"d":"0.56"},{"v":0.120065395502646,"d":"0.12"},{"v":4.67285488566254,"d":"4.67"},{"v":2.22430423536541,"d":"2.22"},1,1,"up","no"]
["ENSG00000103154","NECAB2","ENST00000567703;ENST00000566836;ENST00000565691","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0046872(metal ion binding);GO:0005509(calcium ion binding);GO:0005886(plasma membrane);GO:0042995(cell projection);GO:0005515(protein binding);GO:0030425(dendrite);GO:0030424(axon);GO:0070374(positive regulation of ERK1 and ERK2 cascade);GO:0060168(positive regulation of adenosine receptor signaling pathway);GO:0031687(A2A adenosine receptor binding);GO:0031802(type 5 metabotropic glutamate receptor binding);GO:1900451(positive regulation of glutamate receptor signaling pathway);GO:1904021(negative regulation of G-protein coupled receptor internalization);GO:1905477(positive regulation of protein localization to membrane);GO:1905477(positive regulation of protein localization to membrane)","NA","NA","NA","N-terminal EF-hand calcium binding protein 2 [Source:HGNC Symbol;Acc:HGNC:23746]",{"v":0.181980914285714,"d":"0.18"},{"v":0.674134342857143,"d":"0.67"},{"v":0.269947550089846,"d":"0.27"},{"v":-1.88924897122584,"d":"-1.89"},1,1,"down","no"]
["ENSG00000237346","AL080313.2","ENST00000456440","NA","NA","NA","NA",null,0,{"v":0.110716,"d":"0.11"},"-inf","-inf",1,1,"down","no"]
["ENSG00000021461","CYP3A43","ENST00000354829;ENST00000481362","GO:0016020(membrane);GO:0046872(metal ion binding);GO:0004497(monooxygenase activity);GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005506(iron ion binding);GO:0016705(oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen);GO:0020037(heme binding);GO:0016712(oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen);GO:0070330(aromatase activity);GO:0043231(intracellular membrane-bounded organelle);GO:0031090(organelle membrane);GO:0016021(integral component of membrane);GO:0016021(integral component of membrane)","05204(Chemical carcinogenesis);05204(Chemical carcinogenesis)","K17692","EC:1.14.14.1","cytochrome P450 family 3 subfamily A member 43 [Source:HGNC Symbol;Acc:HGNC:17450]",{"v":0.0274386204019719,"d":"0.03"},{"v":0.0169887258248009,"d":"0.02"},{"v":1.61510761224457,"d":"1.62"},{"v":0.691630292770206,"d":"0.69"},1,1,"up","no"]
["MSTRG.12530","FAM196B","ENST00000377365","NA","NA","NA","NA","family with sequence similarity 196 member B [Source:HGNC Symbol;Acc:HGNC:37271]",{"v":0.083985,"d":"0.08"},{"v":0.100535,"d":"0.10"},{"v":0.835380713184463,"d":"0.84"},{"v":-0.259494259160575,"d":"-0.26"},1,1,"down","no"]
["ENSG00000235772","AP001625.2","ENST00000442605","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000230646","KLF2P2","ENST00000416807","NA","NA","NA","NA","Kruppel like factor 2 pseudogene 2 [Source:HGNC Symbol;Acc:HGNC:49281]",{"v":0.052377,"d":"0.05"},0,"inf","inf",1,1,"up","no"]
["ENSG00000152092","ASTN1","ENST00000361833;ENST00000424564","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0007155(cell adhesion);GO:0005886(plasma membrane);GO:0031410(cytoplasmic vesicle);GO:0005768(endosome);GO:0005575(cellular_component);GO:0043204(perikaryon);GO:0030136(clathrin-coated vesicle);GO:0001764(neuron migration);GO:0007158(neuron cell-cell adhesion);GO:0007626(locomotory behavior);GO:0016337(single organismal cell-cell adhesion);GO:0016477(cell migration);GO:0009897(external side of plasma membrane);GO:0009897(external side of plasma membrane)","NA","NA","NA","astrotactin 1 [Source:HGNC Symbol;Acc:HGNC:773]",{"v":0.016060303880013,"d":"0.02"},{"v":0.0188703559395718,"d":"0.02"},{"v":0.851086430560326,"d":"0.85"},{"v":-0.232622445221642,"d":"-0.23"},1,1,"down","no"]
["ENSG00000261405","AC136944.3","ENST00000567422;ENST00000568520","NA","NA","NA","NA",null,{"v":0.0291640470324748,"d":"0.03"},{"v":0.014305359462486,"d":"0.01"},{"v":2.03867977655185,"d":"2.04"},{"v":1.02763518336745,"d":"1.03"},1,1,"up","no"]
["ENSG00000259133","AL161757.5","ENST00000554597","NA","NA","NA","NA",null,0,{"v":0.0571849455040872,"d":"0.06"},"-inf","-inf",1,1,"down","no"]
["ENSG00000233543","CHTF8P1","ENST00000414660","NA","NA","NA","NA","chromosome transmission fidelity factor 8 pseudogene 1 [Source:HGNC Symbol;Acc:HGNC:35443]",0,{"v":0.023981,"d":"0.02"},"-inf","-inf",1,1,"down","no"]
["ENSG00000240882","AC063952.2","ENST00000498792","NA","NA","NA","NA",null,{"v":0.041892,"d":"0.04"},0,"inf","inf",1,1,"up","no"]
["MSTRG.12476","AC091982.4","ENST00000623943","NA","NA","NA","NA",null,{"v":0.118003,"d":"0.12"},{"v":0.589884,"d":"0.59"},{"v":0.200044415512202,"d":"0.20"},{"v":-2.32160774026187,"d":"-2.32"},1,1,"down","no"]
["ENSG00000228509","AC006460.1","ENST00000421437","NA","NA","NA","NA",null,0,{"v":0.0391933866666667,"d":"0.04"},"-inf","-inf",1,1,"down","no"]
["ENSG00000234785","EEF1GP5","ENST00000434365","NA","NA","NA","NA","eukaryotic translation elongation factor 1 gamma pseudogene 5 [Source:HGNC Symbol;Acc:HGNC:44560]",{"v":0.083621,"d":"0.08"},0,"inf","inf",1,1,"up","no"]
["ENSG00000071539","TRIP13","ENST00000512024;ENST00000166345","GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0005515(protein binding);GO:1903506(regulation of nucleic acid-templated transcription);GO:0051321(meiotic cell cycle);GO:0030154(cell differentiation);GO:0007283(spermatogenesis);GO:0042802(identical protein binding);GO:0007130(synaptonemal complex assembly);GO:0007131(reciprocal meiotic recombination);GO:0048477(oogenesis);GO:0005634(nucleus);GO:0006366(transcription from RNA polymerase II promoter);GO:0003712(transcription cofactor activity);GO:0006302(double-strand break repair);GO:0001556(oocyte maturation);GO:0007141(male meiosis I);GO:0007144(female meiosis I);GO:0007286(spermatid development);GO:0001673(male germ cell nucleus);GO:0001673(male germ cell nucleus)","NA","NA","NA","thyroid hormone receptor interactor 13 [Source:HGNC Symbol;Acc:HGNC:12307]",{"v":0.247432453932584,"d":"0.25"},{"v":0.0354570752808989,"d":"0.04"},{"v":6.97836615040492,"d":"6.98"},{"v":2.80288929680355,"d":"2.80"},1,1,"up","no"]
["ENSG00000186795","KCNK18","ENST00000334549","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005267(potassium channel activity);GO:0006811(ion transport);GO:0006813(potassium ion transport);GO:0071805(potassium ion transmembrane transport);GO:0005886(plasma membrane);GO:0005887(integral component of plasma membrane);GO:0030322(stabilization of membrane potential);GO:0022841(potassium ion leak channel activity);GO:0071435(potassium ion export);GO:0015271(outward rectifier potassium channel activity);GO:0015269(calcium-activated potassium channel activity);GO:0071467(cellular response to pH)","NA","NA","NA","potassium two pore domain channel subfamily K member 18 [Source:HGNC Symbol;Acc:HGNC:19439]",{"v":0.044504,"d":"0.04"},{"v":0.065983,"d":"0.07"},{"v":0.67447675916524,"d":"0.67"},{"v":-0.568159362632604,"d":"-0.57"},1,1,"down","no"]
["ENSG00000172296","SPTLC3","ENST00000476791;ENST00000399002","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016740(transferase activity);GO:0008483(transaminase activity);GO:0003824(catalytic activity);GO:0016746(transferase activity, transferring acyl groups);GO:0006629(lipid metabolic process);GO:0008152(metabolic process);GO:0009058(biosynthetic process);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0030170(pyridoxal phosphate binding);GO:0006665(sphingolipid metabolic process);GO:0030148(sphingolipid biosynthetic process);GO:0004758(serine C-palmitoyltransferase activity);GO:0017059(serine C-palmitoyltransferase complex);GO:0046520(sphingoid biosynthetic process);GO:0046520(sphingoid biosynthetic process)","00600(Sphingolipid metabolism);04071(Sphingolipid signaling pathway);04071(Sphingolipid signaling pathway)","K00654","EC:2.3.1.50","serine palmitoyltransferase long chain base subunit 3 [Source:HGNC Symbol;Acc:HGNC:16253]",{"v":0.0679730559859155,"d":"0.07"},{"v":0.0445529234741784,"d":"0.04"},{"v":1.52566993780578,"d":"1.53"},{"v":0.609442884456081,"d":"0.61"},1,1,"up","no"]
["ENSG00000284696","AL596275.2","ENST00000641957","NA","NA","NA","NA",null,0,{"v":0.024845328174262,"d":"0.02"},"-inf","-inf",1,1,"down","no"]
["ENSG00000239650","GUSBP4","ENST00000423899","NA","NA","NA","NA","glucuronidase, beta pseudogene 4 [Source:HGNC Symbol;Acc:HGNC:18220]",0,{"v":0.364357,"d":"0.36"},"-inf","-inf",1,1,"down","no"]
["MSTRG.8280","AC011466.3","ENST00000596563","NA","NA","NA","NA",null,0,{"v":0.0339128087215064,"d":"0.03"},"-inf","-inf",1,1,"down","no"]
["MSTRG.3440","AC034102.1","ENST00000552016","NA","NA","NA","NA",null,{"v":0.144391,"d":"0.14"},0,"inf","inf",1,1,"up","no"]
["MSTRG.7489","AC023043.1","ENST00000568654","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000258997","NF1P2","ENST00000556855","NA","NA","NA","NA","neurofibromin 1 pseudogene 2 [Source:HGNC Symbol;Acc:HGNC:38664]",0,{"v":5.679E-3,"d":"0.01"},"-inf","-inf",1,1,"down","no"]
["ENSG00000164741","DLC1","ENST00000276297;ENST00000358919;ENST00000506171;ENST00000517868","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0007165(signal transduction);GO:0005829(cytosol);GO:0035023(regulation of Rho protein signal transduction);GO:0043547(positive regulation of GTPase activity);GO:0005515(protein binding);GO:0008289(lipid binding);GO:0006915(apoptotic process);GO:0005901(caveola);GO:0030054(cell junction);GO:0005096(GTPase activator activity);GO:0005925(focal adhesion);GO:0051056(regulation of small GTPase mediated signal transduction);GO:0032956(regulation of actin cytoskeleton organization);GO:0042169(SH2 domain binding);GO:0008285(negative regulation of cell proliferation);GO:0032587(ruffle membrane);GO:0008360(regulation of cell shape);GO:0048041(focal adhesion assembly);GO:0030864(cortical actin cytoskeleton);GO:0030036(actin cytoskeleton organization);GO:0051895(negative regulation of focal adhesion assembly);GO:0006919(activation of cysteine-type endopeptidase activity involved in apoptotic process);GO:0001843(neural tube closure);GO:0030336(negative regulation of cell migration);GO:0003007(heart morphogenesis);GO:0051497(negative regulation of stress fiber assembly);GO:0030900(forebrain development);GO:1900119(positive regulation of execution phase of apoptosis);GO:0035024(negative regulation of Rho protein signal transduction);GO:0035307(positive regulation of protein dephosphorylation);GO:0021575(hindbrain morphogenesis);GO:0021575(hindbrain morphogenesis)","NA","NA","NA","DLC1 Rho GTPase activating protein [Source:HGNC Symbol;Acc:HGNC:2897]",{"v":0.052572526574957,"d":"0.05"},{"v":0.0137614304361419,"d":"0.01"},{"v":3.82028066187689,"d":"3.82"},{"v":1.93367863161809,"d":"1.93"},1,1,"up","no"]
["MSTRG.4765","IGHJ2P","ENST00000454480","NA","NA","NA","NA","immunoglobulin heavy joining 2P (pseudogene) [Source:HGNC Symbol;Acc:HGNC:5535]",{"v":0.042697,"d":"0.04"},0,"inf","inf",1,1,"up","no"]
["MSTRG.8311","AC010643.1","ENST00000599433","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["MSTRG.8746","AC018889.1","ENST00000605372","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000133124","IRS4","ENST00000372129","GO:0016020(membrane);GO:0009967(positive regulation of signal transduction);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0004871(signal transducer activity);GO:0007165(signal transduction);GO:0005158(insulin receptor binding);GO:0005829(cytosol);GO:0008286(insulin receptor signaling pathway);GO:0005070(SH3/SH2 adaptor activity);GO:0043548(phosphatidylinositol 3-kinase binding);GO:0019216(regulation of lipid metabolic process)","04068(FoxO signaling pathway);04022(cGMP - PKG signaling pathway);04152(AMPK signaling pathway);04140(Autophagy - animal);04910(Insulin signaling pathway);04923(Regulation of lipolysis in adipocyte);04920(Adipocytokine signaling pathway);04211(Longevity regulating pathway - mammal);04213(Longevity regulating pathway - multiple species);04930(Type II diabetes mellitus)","K17446","NA","insulin receptor substrate 4 [Source:HGNC Symbol;Acc:HGNC:6128]",{"v":0.050032,"d":"0.05"},{"v":0.05792,"d":"0.06"},{"v":0.863812154696133,"d":"0.86"},{"v":-0.211210478045527,"d":"-0.21"},1,1,"down","no"]
["ENSG00000167968","DNASE1L2","ENST00000564065;ENST00000569184","GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0016787(hydrolase activity);GO:0090305(nucleic acid phosphodiester bond hydrolysis);GO:0005576(extracellular region);GO:0004519(endonuclease activity);GO:0004518(nuclease activity);GO:0004536(deoxyribonuclease activity);GO:0006308(DNA catabolic process);GO:0005634(nucleus);GO:0003677(DNA binding);GO:0006259(DNA metabolic process);GO:0005509(calcium ion binding);GO:0001942(hair follicle development);GO:0003335(corneocyte development);GO:0003335(corneocyte development)","NA","NA","NA","deoxyribonuclease 1 like 2 [Source:HGNC Symbol;Acc:HGNC:2958]",{"v":0.184983247037375,"d":"0.18"},{"v":0.091913,"d":"0.09"},{"v":2.01259067854792,"d":"2.01"},{"v":1.0090537862306,"d":"1.01"},1,1,"up","no"]
["ENSG00000275763","C18orf65","ENST00000622985","NA","NA","NA","NA","chromosome 18 open reading frame 65 [Source:HGNC Symbol;Acc:HGNC:51248]",{"v":0.035407,"d":"0.04"},{"v":0.092185,"d":"0.09"},{"v":0.384086348104355,"d":"0.38"},{"v":-1.38049740899851,"d":"-1.38"},1,1,"down","no"]
["ENSG00000233045","AC097523.1","ENST00000429515","NA","NA","NA","NA",null,{"v":0.498957,"d":"0.50"},{"v":0.447723,"d":"0.45"},{"v":1.1144323610804,"d":"1.11"},{"v":0.156309056889159,"d":"0.16"},1,1,"up","no"]
["ENSG00000273509","CNTNAP3P1","ENST00000616657","NA","NA","NA","NA","contactin associated protein-like 3 pseudogene 1 [Source:HGNC Symbol;Acc:HGNC:49591]",0,0,1,0,1,1,"no","no"]
["MSTRG.9308","AC067945.3","ENST00000429796;ENST00000456176","NA","NA","NA","NA",null,{"v":2.72157590384615,"d":"2.72"},{"v":0.966774711538462,"d":"0.97"},{"v":2.81510870253858,"d":"2.82"},{"v":1.49319063157211,"d":"1.49"},1,1,"up","no"]
["ENSG00000283703","VSIG10L2","ENST00000638636","GO:0016020(membrane);GO:0016021(integral component of membrane)","NA","NA","NA","V-set and immunoglobulin domain containing 10 like 2 [Source:HGNC Symbol;Acc:HGNC:27879]",0,{"v":0.00854541430111391,"d":"0.01"},"-inf","-inf",1,1,"down","no"]
["MSTRG.8760","ACA59","ENST00000515966","NA","NA","NA","NA","Small nucleolar RNA ACA59 [Source:RFAM;Acc:RF01293]",0,{"v":0.212699,"d":"0.21"},"-inf","-inf",1,1,"down","no"]
["ENSG00000225705","AC004899.1","ENST00000424687","NA","NA","NA","NA",null,0,{"v":0.013309,"d":"0.01"},"-inf","-inf",1,1,"down","no"]
["ENSG00000116774","OLFML3","ENST00000491700","GO:0005576(extracellular region);GO:0007275(multicellular organism development);GO:1903561(extracellular vesicle)","NA","NA","NA","olfactomedin like 3 [Source:HGNC Symbol;Acc:HGNC:24956]",{"v":0.0867937227933357,"d":"0.09"},{"v":0.0940723612194257,"d":"0.09"},{"v":0.922627237886456,"d":"0.92"},{"v":-0.11618021047896,"d":"-0.12"},1,1,"down","no"]
["MSTRG.2570","SNX32","ENST00000526972;ENST00000530101;ENST00000308342;ENST00000524729","GO:0006810(transport);GO:0015031(protein transport);GO:0005515(protein binding);GO:0035091(phosphatidylinositol binding);GO:0005768(endosome);GO:0019898(extrinsic component of membrane);GO:0016241(regulation of macroautophagy);GO:0006897(endocytosis);GO:0016050(vesicle organization);GO:0016050(vesicle organization)","04144(Endocytosis);04144(Endocytosis)","K17920","NA","sorting nexin 32 [Source:HGNC Symbol;Acc:HGNC:26423]",{"v":0.164156447302068,"d":"0.16"},{"v":0.105761001765003,"d":"0.11"},{"v":1.55214535190218,"d":"1.55"},{"v":0.634263666190934,"d":"0.63"},1,1,"up","no"]
["ENSG00000232717","TRIM51JP","ENST00000443564","NA","NA","NA","NA","tripartite motif-containing 51J, pseudogene [Source:HGNC Symbol;Acc:HGNC:43978]",{"v":0.015057,"d":"0.02"},0,"inf","inf",1,1,"up","no"]
["ENSG00000264456","AC138207.4","ENST00000580979","NA","NA","NA","NA",null,0,{"v":0.289326,"d":"0.29"},"-inf","-inf",1,1,"down","no"]
["MSTRG.9748","PLCG1-AS1","ENST00000454626","NA","NA","NA","NA","PLCG1 antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:40450]",{"v":0.066098,"d":"0.07"},{"v":0.07307,"d":"0.07"},{"v":0.904584644861092,"d":"0.90"},{"v":-0.144672588162757,"d":"-0.14"},1,1,"down","no"]
["MSTRG.6164","AC092139.4","ENST00000624318","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000159905","ZNF221","ENST00000251269;ENST00000622072","GO:0003676(nucleic acid binding);GO:0006355(regulation of transcription, DNA-templated);GO:0005622(intracellular);GO:0046872(metal ion binding);GO:0046872(metal ion binding)","NA","NA","NA","zinc finger protein 221 [Source:HGNC Symbol;Acc:HGNC:13014]",{"v":0.0916929186602871,"d":"0.09"},{"v":0.0514398159735002,"d":"0.05"},{"v":1.78252812388605,"d":"1.78"},{"v":0.833924839009055,"d":"0.83"},1,1,"up","no"]
["ENSG00000258285","TESC-AS1","ENST00000547006","NA","NA","NA","NA","TESC antisense RNA 1 (head to head) [Source:HGNC Symbol;Acc:HGNC:51142]",0,{"v":0.043327,"d":"0.04"},"-inf","-inf",1,1,"down","no"]
["ENSG00000256283","METTL8P1","ENST00000428182","NA","NA","NA","NA","methyltransferase like 8 pseudogene 1 [Source:HGNC Symbol;Acc:HGNC:49856]",{"v":0.036175,"d":"0.04"},0,"inf","inf",1,1,"up","no"]
["ENSG00000226883","AL035416.1","ENST00000443012","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000116761","CTH","ENST00000482383;ENST00000464926;ENST00000370938;ENST00000411986","GO:0005737(cytoplasm);GO:0003824(catalytic activity);GO:0016829(lyase activity);GO:0005515(protein binding);GO:0008652(cellular amino acid biosynthetic process);GO:0030170(pyridoxal phosphate binding);GO:0042802(identical protein binding);GO:0005516(calmodulin binding);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0051289(protein homotetramerization);GO:0030968(endoplasmic reticulum unfolded protein response);GO:0019344(cysteine biosynthetic process);GO:0070814(hydrogen sulfide biosynthetic process);GO:0003962(cystathionine gamma-synthase activity);GO:0004123(cystathionine gamma-lyase activity);GO:0016846(carbon-sulfur lyase activity);GO:0044540(L-cystine L-cysteine-lyase (deaminating));GO:0047982(homocysteine desulfhydrase activity);GO:0080146(L-cysteine desulfhydrase activity);GO:0000098(sulfur amino acid catabolic process);GO:0006534(cysteine metabolic process);GO:0018272(protein-pyridoxal-5-phosphate linkage via peptidyl-N6-pyridoxal phosphate-L-lysine);GO:0019343(cysteine biosynthetic process via cystathionine);GO:0019346(transsulfuration);GO:0043066(negative regulation of apoptotic process);GO:0043123(positive regulation of I-kappaB kinase/NF-kappaB signaling);GO:0044524(protein sulfhydration);GO:0051092(positive regulation of NF-kappaB transcription factor activity);GO:0071266('de novo' L-methionine biosynthetic process);GO:1904831(positive regulation of aortic smooth muscle cell differentiation);GO:1990830(cellular response to leukemia inhibitory factor);GO:2001234(negative regulation of apoptotic signaling pathway);GO:2001234(negative regulation of apoptotic signaling pathway)","00260(Glycine, serine and threonine metabolism);00270(Cysteine and methionine metabolism);00450(Selenocompound metabolism);00450(Selenocompound metabolism)","K01758","EC:4.4.1.1","cystathionine gamma-lyase [Source:HGNC Symbol;Acc:HGNC:2501]",{"v":0.126482712510356,"d":"0.13"},{"v":0.111067485501243,"d":"0.11"},{"v":1.13879153687098,"d":"1.14"},{"v":0.187503676591451,"d":"0.19"},1,1,"up","no"]
["ENSG00000235109","ZSCAN31","ENST00000344279;ENST00000439158;ENST00000439628;ENST00000447021;ENST00000414429","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding)","NA","NA","NA","zinc finger and SCAN domain containing 31 [Source:HGNC Symbol;Acc:HGNC:14097]",{"v":0.0811939957635667,"d":"0.08"},{"v":0.11105221565463,"d":"0.11"},{"v":0.731133505846279,"d":"0.73"},{"v":-0.45179322682724,"d":"-0.45"},1,1,"down","no"]
["MSTRG.11316","KRT8P12","ENST00000468527","NA","NA","NA","NA","keratin 8 pseudogene 12 [Source:HGNC Symbol;Acc:HGNC:28057]",{"v":0.0316161719589643,"d":"0.03"},{"v":0.0149846262823644,"d":"0.01"},{"v":2.10990727183992,"d":"2.11"},{"v":1.07717959542708,"d":"1.08"},1,1,"up","no"]
["ENSG00000260725","AC005307.1","ENST00000567877","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["MSTRG.2986","KIRREL3-AS3","ENST00000404882","NA","NA","NA","NA","KIRREL3 antisense RNA 3 [Source:HGNC Symbol;Acc:HGNC:26855]",0,{"v":0.0258055673076923,"d":"0.03"},"-inf","-inf",1,1,"down","no"]
["ENSG00000182601","HS3ST4","ENST00000331351","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016740(transferase activity);GO:0005794(Golgi apparatus);GO:0000139(Golgi membrane);GO:0008146(sulfotransferase activity);GO:0008467([heparan sulfate]-glucosamine 3-sulfotransferase 1 activity);GO:0030201(heparan sulfate proteoglycan metabolic process)","NA","NA","NA","heparan sulfate-glucosamine 3-sulfotransferase 4 [Source:HGNC Symbol;Acc:HGNC:5200]",{"v":0.0152121171944362,"d":"0.02"},{"v":0.0386616034329683,"d":"0.04"},{"v":0.393468346981807,"d":"0.39"},{"v":-1.34568051376487,"d":"-1.35"},1,1,"down","no"]
["ENSG00000236279","CLEC2L","ENST00000521281;ENST00000520413","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0030246(carbohydrate binding);GO:0030246(carbohydrate binding)","NA","NA","NA","C-type lectin domain family 2 member L [Source:HGNC Symbol;Acc:HGNC:21969]",{"v":0.0202733161851998,"d":"0.02"},{"v":0.0517969600316581,"d":"0.05"},{"v":0.391399730270055,"d":"0.39"},{"v":-1.35328533314387,"d":"-1.35"},1,1,"down","no"]
["MSTRG.5562","AC141586.5","ENST00000624546","NA","NA","NA","NA",null,{"v":0.050148,"d":"0.05"},0,"inf","inf",1,1,"up","no"]
["ENSG00000138075","ABCG5","ENST00000260645","GO:0042632(cholesterol homeostasis);GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0005515(protein binding);GO:0016887(ATPase activity);GO:0005886(plasma membrane);GO:0042626(ATPase activity, coupled to transmembrane movement of substances);GO:0055085(transmembrane transport);GO:0046982(protein heterodimerization activity);GO:0043235(receptor complex);GO:0033344(cholesterol efflux);GO:0006855(drug transmembrane transport);GO:0016324(apical plasma membrane);GO:0030299(intestinal cholesterol absorption);GO:0017127(cholesterol transporter activity);GO:0007588(excretion);GO:0010949(negative regulation of intestinal phytosterol absorption);GO:0045796(negative regulation of intestinal cholesterol absorption);GO:0043190(ATP-binding cassette (ABC) transporter complex);GO:0007584(response to nutrient);GO:0010212(response to ionizing radiation);GO:0042493(response to drug);GO:0045177(apical part of cell)","02010(ABC transporters);04976(Bile secretion);04975(Fat digestion and absorption);04979(Cholesterol metabolism)","K05683","NA","ATP binding cassette subfamily G member 5 [Source:HGNC Symbol;Acc:HGNC:13886]",{"v":0.0232023494623656,"d":"0.02"},{"v":0.00740536559139785,"d":"0.01"},{"v":3.13318082355282,"d":"3.13"},{"v":1.64762803358224,"d":"1.65"},1,1,"up","no"]
["ENSG00000128276","RFPL3","ENST00000249007","GO:0046872(metal ion binding);GO:0005515(protein binding)","NA","NA","NA","ret finger protein like 3 [Source:HGNC Symbol;Acc:HGNC:9980]",{"v":0.0335607941372418,"d":"0.03"},{"v":0.0303954483677548,"d":"0.03"},{"v":1.10413880825805,"d":"1.10"},{"v":0.142921553816394,"d":"0.14"},1,1,"up","no"]
["ENSG00000150750","C11orf53","ENST00000280325","NA","NA","NA","NA","chromosome 11 open reading frame 53 [Source:HGNC Symbol;Acc:HGNC:30527]",0,{"v":0.0618364113924051,"d":"0.06"},"-inf","-inf",1,1,"down","no"]
["ENSG00000145632","PLK2","ENST00000509422;ENST00000504196;ENST00000503713;ENST00000515415;ENST00000514306;ENST00000510629;ENST00000274289","GO:0005737(cytoplasm);GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0032403(protein complex binding);GO:0000278(mitotic cell cycle);GO:0007093(mitotic cell cycle checkpoint);GO:0007265(Ras protein signal transduction);GO:0007613(memory);GO:0032092(positive regulation of protein binding);GO:0032436(positive regulation of proteasomal ubiquitin-dependent protein catabolic process);GO:0032486(Rap protein signal transduction);GO:0043066(negative regulation of apoptotic process);GO:0048167(regulation of synaptic plasticity);GO:0060291(long-term synaptic potentiation);GO:0060292(long term synaptic depression);GO:0061000(negative regulation of dendritic spine development);GO:0000785(chromatin);GO:0005622(intracellular);GO:0030425(dendrite);GO:0005856(cytoskeleton);GO:0042995(cell projection);GO:0005515(protein binding);GO:0004871(signal transducer activity);GO:0005813(centrosome);GO:0006977(DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest);GO:0005829(cytosol);GO:0005814(centriole);GO:0043123(positive regulation of I-kappaB kinase/NF-kappaB signaling);GO:0007052(mitotic spindle organization);GO:0045732(positive regulation of protein catabolic process);GO:0018105(peptidyl-serine phosphorylation);GO:0000082(G1/S transition of mitotic cell cycle);GO:0046599(regulation of centriole replication);GO:0010508(positive regulation of autophagy);GO:0043008(ATP-dependent protein binding);GO:0043008(ATP-dependent protein binding)","04068(FoxO signaling pathway);04068(FoxO signaling pathway)","K08861","EC:2.7.11.21","polo like kinase 2 [Source:HGNC Symbol;Acc:HGNC:19699]",{"v":0.0611406078020134,"d":"0.06"},{"v":0.120087748531879,"d":"0.12"},{"v":0.509132767909149,"d":"0.51"},{"v":-0.973886174092719,"d":"-0.97"},1,1,"down","no"]
["ENSG00000133116","KL","ENST00000487852;ENST00000380099","GO:0005622(intracellular);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005615(extracellular space);GO:0016787(hydrolase activity);GO:0004871(signal transducer activity);GO:0005975(carbohydrate metabolic process);GO:0005886(plasma membrane);GO:0043547(positive regulation of GTPase activity);GO:0008152(metabolic process);GO:0005576(extracellular region);GO:0004553(hydrolase activity, hydrolyzing O-glycosyl compounds);GO:0016798(hydrolase activity, acting on glycosyl bonds);GO:0005179(hormone activity);GO:0036092(phosphatidylinositol-3-phosphate biosynthetic process);GO:0046854(phosphatidylinositol phosphorylation);GO:0008543(fibroblast growth factor receptor signaling pathway);GO:0008286(insulin receptor signaling pathway);GO:0070062(extracellular exosome);GO:0000165(MAPK cascade);GO:0005887(integral component of plasma membrane);GO:0030501(positive regulation of bone mineralization);GO:0016324(apical plasma membrane);GO:0046934(phosphatidylinositol-4,5-bisphosphate 3-kinase activity);GO:0014066(regulation of phosphatidylinositol 3-kinase signaling);GO:0038111(interleukin-7-mediated signaling pathway);GO:0048015(phosphatidylinositol-mediated signaling);GO:0005088(Ras guanyl-nucleotide exchange factor activity);GO:0016303(1-phosphatidylinositol-3-kinase activity);GO:0007568(aging);GO:0005499(vitamin D binding);GO:0017134(fibroblast growth factor binding);GO:0004566(beta-glucuronidase activity);GO:1901657(glycosyl compound metabolic process);GO:0005104(fibroblast growth factor receptor binding);GO:0008422(beta-glucosidase activity);GO:0006112(energy reserve metabolic process);GO:0055074(calcium ion homeostasis);GO:0090080(positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway);GO:0090080(positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway)","00040(Pentose and glucuronate interconversions);04961(Endocrine and other factor-regulated calcium reabsorption);04211(Longevity regulating pathway - mammal);04211(Longevity regulating pathway - mammal)","K14756","EC:3.2.1.31","klotho [Source:HGNC Symbol;Acc:HGNC:6344]",{"v":0.0763504109968354,"d":"0.08"},{"v":0.288809367879747,"d":"0.29"},{"v":0.264362654014138,"d":"0.26"},{"v":-1.91940971030387,"d":"-1.92"},1,1,"down","no"]
["ENSG00000268392","AC003682.1","ENST00000599190","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000168124","OR1F1","ENST00000304646","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0004930(G-protein coupled receptor activity);GO:0007186(G-protein coupled receptor signaling pathway);GO:0005886(plasma membrane);GO:0004871(signal transducer activity);GO:0007165(signal transduction);GO:0004984(olfactory receptor activity);GO:0007608(sensory perception of smell);GO:0050896(response to stimulus);GO:0050911(detection of chemical stimulus involved in sensory perception of smell)","04740(Olfactory transduction)","K04257","NA","olfactory receptor family 1 subfamily F member 1 [Source:HGNC Symbol;Acc:HGNC:8194]",0,0,1,0,1,1,"no","no"]
["ENSG00000144908","ALDH1L1","ENST00000393434;ENST00000467370;ENST00000455064","GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0003824(catalytic activity);GO:0008152(metabolic process);GO:0009058(biosynthetic process);GO:0006730(one-carbon metabolic process);GO:0016742(hydroxymethyl-, formyl- and related transferase activity);GO:0070062(extracellular exosome);GO:0004029(aldehyde dehydrogenase (NAD) activity);GO:0016155(formyltetrahydrofolate dehydrogenase activity);GO:0009258(10-formyltetrahydrofolate catabolic process);GO:0046655(folic acid metabolic process);GO:0005739(mitochondrion);GO:0005739(mitochondrion)","00670(One carbon pool by folate);00670(One carbon pool by folate)","K00289","EC:1.5.1.6","aldehyde dehydrogenase 1 family member L1 [Source:HGNC Symbol;Acc:HGNC:3978]",{"v":0.0297832330805134,"d":"0.03"},{"v":0.00860707956534422,"d":"0.01"},{"v":3.46031808517647,"d":"3.46"},{"v":1.79090466179672,"d":"1.79"},1,1,"up","no"]
["ENSG00000127588","GNG13","ENST00000248150","GO:0016020(membrane);GO:0007186(G-protein coupled receptor signaling pathway);GO:0004871(signal transducer activity);GO:0005886(plasma membrane);GO:0007165(signal transduction);GO:0005834(heterotrimeric G-protein complex);GO:0071377(cellular response to glucagon stimulus);GO:0031681(G-protein beta-subunit binding);GO:0007200(phospholipase C-activating G-protein coupled receptor signaling pathway);GO:0050909(sensory perception of taste);GO:0030425(dendrite)","04014(Ras signaling pathway);04371(Apelin signaling pathway);04151(PI3K-Akt signaling pathway);04062(Chemokine signaling pathway);04926(Relaxin signaling pathway);04724(Glutamatergic synapse);04727(GABAergic synapse);04725(Cholinergic synapse);04728(Dopaminergic synapse);04726(Serotonergic synapse);04723(Retrograde endocannabinoid signaling);04740(Olfactory transduction);04742(Taste transduction);04713(Circadian entrainment);05200(Pathways in cancer);05032(Morphine addiction);05034(Alcoholism);05167(Kaposi's sarcoma-associated herpesvirus infection)","K04547","NA","G protein subunit gamma 13 [Source:HGNC Symbol;Acc:HGNC:14131]",{"v":0.028697,"d":"0.03"},0,"inf","inf",1,1,"up","no"]
["ENSG00000254054","AC087273.2","ENST00000519038","NA","NA","NA","NA",null,0,{"v":0.143924,"d":"0.14"},"-inf","-inf",1,1,"down","no"]
["ENSG00000226465","AL390198.1","ENST00000376445","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000102383","ZDHHC15","ENST00000373367;ENST00000541184","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016740(transferase activity);GO:0005794(Golgi apparatus);GO:0016746(transferase activity, transferring acyl groups);GO:0019706(protein-cysteine S-palmitoyltransferase activity);GO:0016409(palmitoyltransferase activity);GO:0070062(extracellular exosome);GO:0018345(protein palmitoylation);GO:0016188(synaptic vesicle maturation);GO:0045184(establishment of protein localization);GO:0045184(establishment of protein localization)","NA","NA","NA","zinc finger DHHC-type containing 15 [Source:HGNC Symbol;Acc:HGNC:20342]",{"v":0.0212791302052786,"d":"0.02"},{"v":0.00851817536656892,"d":"0.01"},{"v":2.49808548069957,"d":"2.50"},{"v":1.32082284462857,"d":"1.32"},1,1,"up","no"]
["ENSG00000226476","LINC01748","ENST00000635048","NA","NA","NA","NA","long intergenic non-protein coding RNA 1748 [Source:HGNC Symbol;Acc:HGNC:52535]",0,0,1,0,1,1,"no","no"]
["MSTRG.10381","AC004542.2","ENST00000602847","NA","NA","NA","NA",null,0,{"v":0.294338,"d":"0.29"},"-inf","-inf",1,1,"down","no"]
["ENSG00000089356","FXYD3","ENST00000435734","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005216(ion channel activity);GO:0006811(ion transport);GO:0005886(plasma membrane);GO:0005254(chloride channel activity);GO:0006821(chloride transport);GO:0034707(chloride channel complex);GO:1902476(chloride transmembrane transport);GO:0017080(sodium channel regulator activity);GO:2000649(regulation of sodium ion transmembrane transporter activity);GO:0070062(extracellular exosome);GO:0034220(ion transmembrane transport);GO:0005887(integral component of plasma membrane);GO:1903779(regulation of cardiac conduction)","NA","NA","NA","FXYD domain containing ion transport regulator 3 [Source:HGNC Symbol;Acc:HGNC:4027]",{"v":0.0115247942411518,"d":"0.01"},0,"inf","inf",1,1,"up","no"]
["MSTRG.7858","JUNB","ENST00000302754","GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0006355(regulation of transcription, DNA-templated);GO:0006366(transcription from RNA polymerase II promoter);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0005515(protein binding);GO:0051726(regulation of cell cycle);GO:0032870(cellular response to hormone stimulus);GO:0000790(nuclear chromatin);GO:0008134(transcription factor binding);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0000981(RNA polymerase II transcription factor activity, sequence-specific DNA binding);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:0003713(transcription coactivator activity);GO:0032496(response to lipopolysaccharide);GO:0042127(regulation of cell proliferation);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0003714(transcription corepressor activity);GO:0034097(response to cytokine);GO:0042493(response to drug);GO:0000785(chromatin);GO:0009314(response to radiation);GO:0035976(transcription factor AP-1 complex);GO:0009612(response to mechanical stimulus);GO:0045597(positive regulation of cell differentiation);GO:0051591(response to cAMP);GO:0000977(RNA polymerase II regulatory region sequence-specific DNA binding);GO:0001077(transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0001570(vasculogenesis);GO:0001649(osteoblast differentiation);GO:0001701(in utero embryonic development);GO:0001829(trophectodermal cell differentiation);GO:0009987(cellular process);GO:0010941(regulation of cell death);GO:0030316(osteoclast differentiation);GO:0033687(osteoblast proliferation);GO:0046697(decidualization);GO:0060136(embryonic process involved in female pregnancy);GO:0060716(labyrinthine layer blood vessel development);GO:0071277(cellular response to calcium ion)","04668(TNF signaling pathway);04380(Osteoclast differentiation)","K09028","NA","JunB proto-oncogene, AP-1 transcription factor subunit [Source:HGNC Symbol;Acc:HGNC:6205]",0,0,1,0,1,1,"no","no"]
["ENSG00000140279","DUOX2","ENST00000389039;ENST00000558383","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0005509(calcium ion binding);GO:0020037(heme binding);GO:0098869(cellular oxidant detoxification);GO:0006979(response to oxidative stress);GO:0004601(peroxidase activity);GO:0016174(NAD(P)H oxidase activity);GO:0050665(hydrogen peroxide biosynthetic process);GO:0046872(metal ion binding);GO:0005886(plasma membrane);GO:0030054(cell junction);GO:0042446(hormone biosynthetic process);GO:0070062(extracellular exosome);GO:0042744(hydrogen peroxide catabolic process);GO:0009615(response to virus);GO:0016324(apical plasma membrane);GO:0006590(thyroid hormone generation);GO:0019221(cytokine-mediated signaling pathway);GO:0051591(response to cAMP);GO:0009566(fertilization);GO:0030282(bone mineralization);GO:0030878(thyroid gland development);GO:0035264(multicellular organism growth);GO:0042335(cuticle development);GO:0042403(thyroid hormone metabolic process);GO:0042445(hormone metabolic process);GO:0048839(inner ear development);GO:0048855(adenohypophysis morphogenesis);GO:0048855(adenohypophysis morphogenesis)","04918(Thyroid hormone synthesis);04918(Thyroid hormone synthesis)","K13411","EC:1.6.3.1;EC:1.11.1.-","dual oxidase 2 [Source:HGNC Symbol;Acc:HGNC:13273]",{"v":0.0239883670937564,"d":"0.02"},{"v":0.0200447639821029,"d":"0.02"},{"v":1.19673981270992,"d":"1.20"},{"v":0.259109525117273,"d":"0.26"},1,1,"up","no"]
["ENSG00000179172","HNRNPCL1","ENST00000317869","GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0005634(nucleus);GO:0030529(intracellular ribonucleoprotein complex)","NA","NA","NA","heterogeneous nuclear ribonucleoprotein C-like 1 [Source:HGNC Symbol;Acc:HGNC:29295]",{"v":0.062812,"d":"0.06"},{"v":0.057922,"d":"0.06"},{"v":1.08442388039087,"d":"1.08"},{"v":0.11692878861484,"d":"0.12"},1,1,"up","no"]
["MSTRG.5958","AC018552.3","ENST00000567416","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["MSTRG.11467","TM4SF19-AS1","ENST00000444939;ENST00000452051;ENST00000420226","NA","NA","NA","NA","TM4SF19 antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:41085]",{"v":0.0244542771535581,"d":"0.02"},0,"inf","inf",1,1,"up","no"]
["ENSG00000185888","PRSS38","ENST00000366757","GO:0016787(hydrolase activity);GO:0008233(peptidase activity);GO:0006508(proteolysis);GO:0005576(extracellular region);GO:0004252(serine-type endopeptidase activity);GO:0008236(serine-type peptidase activity)","NA","NA","NA","protease, serine 38 [Source:HGNC Symbol;Acc:HGNC:29625]",{"v":0.1251,"d":"0.13"},{"v":0.032878,"d":"0.03"},{"v":3.80497597177444,"d":"3.80"},{"v":1.92788734321336,"d":"1.93"},1,1,"up","no"]
["ENSG00000186862","PDZD7","ENST00000619208;ENST00000476306;ENST00000474125","GO:0005634(nucleus);GO:0042995(cell projection);GO:0005615(extracellular space);GO:0005515(protein binding);GO:0005929(cilium);GO:0042803(protein homodimerization activity);GO:0046982(protein heterodimerization activity);GO:0045184(establishment of protein localization);GO:0050910(detection of mechanical stimulus involved in sensory perception of sound);GO:0060088(auditory receptor cell stereocilium organization);GO:0060117(auditory receptor cell development);GO:0002141(stereocilia ankle link);GO:1990696(USH2 complex);GO:1990696(USH2 complex)","NA","NA","NA","PDZ domain containing 7 [Source:HGNC Symbol;Acc:HGNC:26257]",{"v":0.106612850369352,"d":"0.11"},{"v":0.0695148058752792,"d":"0.07"},{"v":1.53367112267612,"d":"1.53"},{"v":0.61698914740881,"d":"0.62"},1,1,"up","no"]
["MSTRG.3611","AC123567.2","ENST00000550759","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000282299","AC073488.5","ENST00000631993","NA","NA","NA","NA",null,0,{"v":0.030255,"d":"0.03"},"-inf","-inf",1,1,"down","no"]
["ENSG00000267757","EML2-AS1","ENST00000587092;ENST00000623430;ENST00000591087","NA","NA","NA","NA","EML2 antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:48331]",{"v":0.0414820178137652,"d":"0.04"},0,"inf","inf",1,1,"up","no"]
["MSTRG.9816","AL035685.1","ENST00000637091;ENST00000637575;ENST00000637341;ENST00000636663","NA","NA","NA","NA",null,0,{"v":0.0227939913945837,"d":"0.02"},"-inf","-inf",1,1,"down","no"]
["ENSG00000241493","AC018638.3","ENST00000461273","NA","NA","NA","NA",null,{"v":0.124611,"d":"0.12"},0,"inf","inf",1,1,"up","no"]
["MSTRG.2749","AP002812.5","ENST00000530972","NA","NA","NA","NA",null,{"v":0.058854,"d":"0.06"},{"v":0.097181,"d":"0.10"},{"v":0.605612208147683,"d":"0.61"},{"v":-0.723533806907511,"d":"-0.72"},1,1,"down","no"]
["ENSG00000280061","AC011504.1","ENST00000623331","NA","NA","NA","NA",null,{"v":1.25E-4,"d":"0.00"},0,"inf","inf",1,1,"up","no"]
["MSTRG.3732","AC073575.2","ENST00000614212","NA","NA","NA","NA",null,0,{"v":0.418401,"d":"0.42"},"-inf","-inf",1,1,"down","no"]
["ENSG00000272953","AC092171.4","ENST00000609130","NA","NA","NA","NA",null,{"v":0.549807,"d":"0.55"},{"v":0.346029,"d":"0.35"},{"v":1.58890439818628,"d":"1.59"},{"v":0.668032322665153,"d":"0.67"},1,1,"up","no"]
["ENSG00000224963","U82695.1","ENST00000635752","NA","NA","NA","NA",null,0,{"v":0.0412720784494693,"d":"0.04"},"-inf","-inf",1,1,"down","no"]
["ENSG00000228203","RNF144A-AS1","ENST00000437589;ENST00000418970;ENST00000424351","NA","NA","NA","NA","RNF144A antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:30963]",{"v":0.0211611863166954,"d":"0.02"},{"v":0.0382817715146299,"d":"0.04"},{"v":0.552774479326495,"d":"0.55"},{"v":-0.855237084441614,"d":"-0.86"},1,1,"down","no"]
["ENSG00000267414","AC120049.1","ENST00000592638","NA","NA","NA","NA",null,{"v":0.089611,"d":"0.09"},0,"inf","inf",1,1,"up","no"]
["ENSG00000221937","TAS2R40","ENST00000408947","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0004930(G-protein coupled receptor activity);GO:0007186(G-protein coupled receptor signaling pathway);GO:0004871(signal transducer activity);GO:0007165(signal transduction);GO:0050896(response to stimulus);GO:0005886(plasma membrane);GO:0050909(sensory perception of taste);GO:0001580(detection of chemical stimulus involved in sensory perception of bitter taste);GO:0033038(bitter taste receptor activity)","04742(Taste transduction)","K08474","NA","taste 2 receptor member 40 [Source:HGNC Symbol;Acc:HGNC:18885]",{"v":0.343337,"d":"0.34"},0,"inf","inf",1,1,"up","no"]
["MSTRG.2580","AP001107.1","ENST00000501708","NA","NA","NA","NA",null,{"v":0.206437,"d":"0.21"},{"v":0.030017,"d":"0.03"},{"v":6.87733617616684,"d":"6.88"},{"v":2.78184986876226,"d":"2.78"},1,1,"up","no"]
["ENSG00000236499","LINC00896","ENST00000609602","NA","NA","NA","NA","long intergenic non-protein coding RNA 896 [Source:HGNC Symbol;Acc:HGNC:26519]",{"v":0.018076,"d":"0.02"},{"v":0.086152,"d":"0.09"},{"v":0.209815210325936,"d":"0.21"},{"v":-2.25280882656999,"d":"-2.25"},1,1,"down","no"]
["MSTRG.15515","FAM223B","ENST00000598177;ENST00000593346","NA","NA","NA","NA","family with sequence similarity 223 member B (non-protein coding) [Source:HGNC Symbol;Acc:HGNC:34048]",{"v":0.107417701262272,"d":"0.11"},{"v":0.191966152875175,"d":"0.19"},{"v":0.559565838317965,"d":"0.56"},{"v":-0.837620206712177,"d":"-0.84"},1,1,"down","no"]
["MSTRG.8894","AC016700.3","ENST00000455541","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000243469","RPL7P51","ENST00000490532","NA","NA","NA","NA","ribosomal protein L7 pseudogene 51 [Source:HGNC Symbol;Acc:HGNC:36432]",0,0,1,0,1,1,"no","no"]
["ENSG00000257579","AC007540.1","ENST00000548473","NA","NA","NA","NA",null,0,{"v":0.132031,"d":"0.13"},"-inf","-inf",1,1,"down","no"]
["ENSG00000277234","RNU1-5P","ENST00000362684","NA","NA","NA","NA","RNA, U1 small nuclear 5, pseudogene [Source:HGNC Symbol;Acc:HGNC:48304]",0,0,1,0,1,1,"no","no"]
["ENSG00000273058","AL359921.2","ENST00000608547","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000243199","AC115223.1","ENST00000466377","NA","NA","NA","NA",null,{"v":1.199807,"d":"1.20"},0,"inf","inf",1,1,"up","no"]
["MSTRG.4831","IGHVIII-44","ENST00000636235","NA","NA","NA","NA","immunoglobulin heavy variable (III)-44 (pseudogene) [Source:HGNC Symbol;Acc:HGNC:5700]",{"v":0.030829,"d":"0.03"},0,"inf","inf",1,1,"up","no"]
["ENSG00000284465","AC233724.21","ENST00000640846","GO:0005634(nucleus);GO:0046982(protein heterodimerization activity);GO:0006367(transcription initiation from RNA polymerase II promoter)","NA","NA","NA",null,0,{"v":0.020743,"d":"0.02"},"-inf","-inf",1,1,"down","no"]
["ENSG00000258655","ARHGAP5-AS1","ENST00000553596","NA","NA","NA","NA","ARHGAP5 antisense RNA 1 (head to head) [Source:HGNC Symbol;Acc:HGNC:20279]",{"v":0.05563,"d":"0.06"},{"v":0.131671,"d":"0.13"},{"v":0.42249242429996,"d":"0.42"},{"v":-1.24300262218572,"d":"-1.24"},1,1,"down","no"]
["ENSG00000228368","AC106873.1","ENST00000420664","NA","NA","NA","NA",null,0,{"v":0.043772,"d":"0.04"},"-inf","-inf",1,1,"down","no"]
["ENSG00000226329","AC005682.1","ENST00000452069","NA","NA","NA","NA",null,{"v":0.034688,"d":"0.03"},{"v":0.060645,"d":"0.06"},{"v":0.571984499958776,"d":"0.57"},{"v":-0.805952042526342,"d":"-0.81"},1,1,"down","no"]
["ENSG00000213713","PIGCP1","ENST00000527583","NA","NA","NA","NA","phosphatidylinositol glycan anchor biosynthesis class C pseudogene 1 [Source:HGNC Symbol;Acc:HGNC:8961]",{"v":1.28758,"d":"1.29"},0,"inf","inf",1,1,"up","no"]
["ENSG00000249375","CASC11","ENST00000518376;ENST00000502463;ENST00000519071","NA","NA","NA","NA","cancer susceptibility 11 (non-protein coding) [Source:HGNC Symbol;Acc:HGNC:48939]",{"v":0.0387875964087217,"d":"0.04"},0,"inf","inf",1,1,"up","no"]
["ENSG00000223821","AL603910.1","ENST00000423099","NA","NA","NA","NA",null,{"v":0.13708,"d":"0.14"},{"v":0.036894,"d":"0.04"},{"v":3.71550929690465,"d":"3.72"},{"v":1.89355997920489,"d":"1.89"},1,1,"up","no"]
["MSTRG.716","AC126124.2","ENST00000413542","NA","NA","NA","NA",null,{"v":0.296776,"d":"0.30"},0,"inf","inf",1,1,"up","no"]
["ENSG00000250329","KDELC1P1","ENST00000512118","NA","NA","NA","NA","KDEL motif containing 1 pseudogene 1 [Source:HGNC Symbol;Acc:HGNC:39193]",{"v":0.068127,"d":"0.07"},{"v":0.060469,"d":"0.06"},{"v":1.12664340405828,"d":"1.13"},{"v":0.172030957742307,"d":"0.17"},1,1,"up","no"]
["ENSG00000213205","STRADBP1","ENST00000478954","NA","NA","NA","NA","STE20-related kinase adaptor beta pseudogene 1 [Source:HGNC Symbol;Acc:HGNC:22478]",{"v":0.134736,"d":"0.13"},{"v":0.032885,"d":"0.03"},{"v":4.09718716740155,"d":"4.10"},{"v":2.03463379941189,"d":"2.03"},1,1,"up","no"]
["ENSG00000214107","MAGEB1","ENST00000378981","NA","NA","NA","NA","MAGE family member B1 [Source:HGNC Symbol;Acc:HGNC:6808]",{"v":0.0260188065007618,"d":"0.03"},{"v":0.023171000507872,"d":"0.02"},{"v":1.12290388548057,"d":"1.12"},{"v":0.167234446104669,"d":"0.17"},1,1,"up","no"]
["ENSG00000179111","HES7","ENST00000577735;ENST00000541682","GO:0005634(nucleus);GO:0046983(protein dimerization activity);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0007275(multicellular organism development);GO:0007219(Notch signaling pathway);GO:0008134(transcription factor binding);GO:0007498(mesoderm development);GO:0000977(RNA polymerase II regulatory region sequence-specific DNA binding);GO:0001501(skeletal system development);GO:0001756(somitogenesis);GO:0014807(regulation of somitogenesis);GO:0036342(post-anal tail morphogenesis);GO:0045892(negative regulation of transcription, DNA-templated);GO:0048511(rhythmic process);GO:0048511(rhythmic process)","05165(Human papillomavirus infection);05165(Human papillomavirus infection)","K09087","NA","hes family bHLH transcription factor 7 [Source:HGNC Symbol;Acc:HGNC:15977]",{"v":0.0968885749464668,"d":"0.10"},{"v":0.104859790149893,"d":"0.10"},{"v":0.92398215567634,"d":"0.92"},{"v":-0.11406310489737,"d":"-0.11"},1,1,"down","no"]
["MSTRG.12329","MTND5P11","ENST00000511037","NA","NA","NA","NA","mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 5 pseudogene 11 [Source:HGNC Symbol;Acc:HGNC:42273]",{"v":0.381733,"d":"0.38"},{"v":0.168865,"d":"0.17"},{"v":2.26058093743523,"d":"2.26"},{"v":1.17669357257662,"d":"1.18"},1,1,"up","no"]
["ENSG00000265158","LRRC37A7P","ENST00000583900","NA","NA","NA","NA","leucine rich repeat containing 37 member A7, pseudogene [Source:HGNC Symbol;Acc:HGNC:43792]",0,{"v":0.012954,"d":"0.01"},"-inf","-inf",1,1,"down","no"]
["ENSG00000260496","AC009041.1","ENST00000565401;ENST00000599946","NA","NA","NA","NA",null,{"v":0.364621690974729,"d":"0.36"},{"v":0.336932542960289,"d":"0.34"},{"v":1.08218009388812,"d":"1.08"},{"v":0.11394060908961,"d":"0.11"},1,1,"up","no"]
["ENSG00000241067","AC136624.1","ENST00000400791","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["MSTRG.13803","MIR25","ENST00000384816","GO:0005615(extracellular space);GO:1903231(mRNA binding involved in posttranscriptional gene silencing);GO:0035195(gene silencing by miRNA);GO:0055022(negative regulation of cardiac muscle tissue growth);GO:1903243(negative regulation of cardiac muscle hypertrophy in response to stress)","05206(MicroRNAs in cancer)","K17038","NA","microRNA 25 [Source:HGNC Symbol;Acc:HGNC:31609]",{"v":0.324194,"d":"0.32"},{"v":0.840543,"d":"0.84"},{"v":0.385695913237038,"d":"0.39"},{"v":-1.37446423537102,"d":"-1.37"},1,1,"down","no"]
["ENSG00000186150","UBL4B","ENST00000334179","GO:0005737(cytoplasm);GO:0005515(protein binding);GO:1903955(positive regulation of protein targeting to mitochondrion)","NA","NA","NA","ubiquitin like 4B [Source:HGNC Symbol;Acc:HGNC:32309]",0,{"v":0.030869,"d":"0.03"},"-inf","-inf",1,1,"down","no"]
["ENSG00000134962","KLB","ENST00000257408","GO:0005622(intracellular);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005975(carbohydrate metabolic process);GO:0005886(plasma membrane);GO:0043547(positive regulation of GTPase activity);GO:0005515(protein binding);GO:0004553(hydrolase activity, hydrolyzing O-glycosyl compounds);GO:0036092(phosphatidylinositol-3-phosphate biosynthetic process);GO:0046854(phosphatidylinositol phosphorylation);GO:0005887(integral component of plasma membrane);GO:0000165(MAPK cascade);GO:0046934(phosphatidylinositol-4,5-bisphosphate 3-kinase activity);GO:0014066(regulation of phosphatidylinositol 3-kinase signaling);GO:0038111(interleukin-7-mediated signaling pathway);GO:0048015(phosphatidylinositol-mediated signaling);GO:0005088(Ras guanyl-nucleotide exchange factor activity);GO:0016303(1-phosphatidylinositol-3-kinase activity);GO:0008543(fibroblast growth factor receptor signaling pathway);GO:0005104(fibroblast growth factor receptor binding);GO:0017134(fibroblast growth factor binding);GO:1901657(glycosyl compound metabolic process);GO:0008284(positive regulation of cell proliferation);GO:0090080(positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway)","NA","NA","NA","klotho beta [Source:HGNC Symbol;Acc:HGNC:15527]",{"v":0.025158,"d":"0.03"},{"v":0.024905,"d":"0.02"},{"v":1.01015860269022,"d":"1.01"},{"v":0.0145818250075962,"d":"0.01"},1,1,"up","no"]
["ENSG00000272817","AL359198.1","ENST00000610263","NA","NA","NA","NA",null,{"v":0.270063,"d":"0.27"},{"v":0.239705,"d":"0.24"},{"v":1.12664733735216,"d":"1.13"},{"v":0.172035994414652,"d":"0.17"},1,1,"up","no"]
["ENSG00000278694","AL354980.1","ENST00000612670","NA","NA","NA","NA",null,{"v":0.124478,"d":"0.12"},{"v":0.041919,"d":"0.04"},{"v":2.96948877597271,"d":"2.97"},{"v":1.57021457956059,"d":"1.57"},1,1,"up","no"]
["ENSG00000184999","SLC22A10","ENST00000533483","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0055085(transmembrane transport);GO:0022857(transmembrane transporter activity);GO:0006810(transport);GO:0015698(inorganic anion transport);GO:1903825(organic acid transmembrane transport);GO:0015347(sodium-independent organic anion transmembrane transporter activity);GO:0043252(sodium-independent organic anion transport);GO:0005887(integral component of plasma membrane);GO:0015143(urate transmembrane transporter activity);GO:0015747(urate transport);GO:0005452(inorganic anion exchanger activity)","NA","NA","NA","solute carrier family 22 member 10 [Source:HGNC Symbol;Acc:HGNC:18057]",{"v":0.016063158125,"d":"0.02"},{"v":0.017182950625,"d":"0.02"},{"v":0.934831186771219,"d":"0.93"},{"v":-0.0972222304182421,"d":"-0.10"},1,1,"down","no"]
["MSTRG.14924","AL162727.2","ENST00000428429","NA","NA","NA","NA",null,{"v":0.73301,"d":"0.73"},0,"inf","inf",1,1,"up","no"]
["ENSG00000275152","CCL16","ENST00000610493;ENST00000611905","GO:0005576(extracellular region);GO:0006955(immune response);GO:0005125(cytokine activity);GO:0005615(extracellular space);GO:0008009(chemokine activity);GO:0006935(chemotaxis);GO:0060326(cell chemotaxis);GO:0006954(inflammatory response);GO:0050918(positive chemotaxis);GO:0007186(G-protein coupled receptor signaling pathway);GO:0048020(CCR chemokine receptor binding);GO:0002548(monocyte chemotaxis);GO:0030593(neutrophil chemotaxis);GO:0043547(positive regulation of GTPase activity);GO:0048247(lymphocyte chemotaxis);GO:0070098(chemokine-mediated signaling pathway);GO:0070374(positive regulation of ERK1 and ERK2 cascade);GO:0071346(cellular response to interferon-gamma);GO:0071347(cellular response to interleukin-1);GO:0071356(cellular response to tumor necrosis factor);GO:0007267(cell-cell signaling);GO:0042056(chemoattractant activity);GO:0007154(cell communication);GO:0007154(cell communication)","04060(Cytokine-cytokine receptor interaction);04062(Chemokine signaling pathway);04062(Chemokine signaling pathway)","K21093","NA","C-C motif chemokine ligand 16 [Source:HGNC Symbol;Acc:HGNC:10614]",{"v":0.0181844048165138,"d":"0.02"},{"v":0.0468388348623853,"d":"0.05"},{"v":0.388233500469011,"d":"0.39"},{"v":-1.36500348205159,"d":"-1.37"},1,1,"down","no"]
["ENSG00000268895","A1BG-AS1","ENST00000594950;ENST00000595302;ENST00000593960;ENST00000600686;ENST00000600379","NA","NA","NA","NA","A1BG antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:37133]",{"v":0.268165863229502,"d":"0.27"},{"v":0.141210939849624,"d":"0.14"},{"v":1.89904453235049,"d":"1.90"},{"v":0.925273736897581,"d":"0.93"},1,1,"up","no"]
["ENSG00000250640","AC090835.1","ENST00000515189","NA","NA","NA","NA",null,0,{"v":0.044555,"d":"0.04"},"-inf","-inf",1,1,"down","no"]
["ENSG00000249635","AC109361.1","ENST00000513220","NA","NA","NA","NA",null,{"v":0.005793,"d":"0.01"},{"v":0.038041,"d":"0.04"},{"v":0.152283063010962,"d":"0.15"},{"v":-2.71517260131477,"d":"-2.72"},1,1,"down","no"]
["MSTRG.15494","TMEM187","ENST00000369982","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0003674(molecular_function);GO:0008150(biological_process);GO:0030133(transport vesicle)","NA","NA","NA","transmembrane protein 187 [Source:HGNC Symbol;Acc:HGNC:13705]",{"v":0.507371351351351,"d":"0.51"},{"v":0.165991101871102,"d":"0.17"},{"v":3.05661776825449,"d":"3.06"},{"v":1.61193615368989,"d":"1.61"},1,1,"up","no"]
["ENSG00000221955","SLC12A8","ENST00000479231;ENST00000393469","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0055085(transmembrane transport);GO:0015293(symporter activity);GO:0006811(ion transport);GO:0006813(potassium ion transport);GO:0071805(potassium ion transmembrane transport);GO:1902476(chloride transmembrane transport);GO:0015379(potassium:chloride symporter activity);GO:0022820(potassium ion symporter activity);GO:0006821(chloride transport);GO:0006821(chloride transport)","NA","NA","NA","solute carrier family 12 member 8 [Source:HGNC Symbol;Acc:HGNC:15595]",{"v":0.00920187325456498,"d":"0.01"},{"v":0.0275539692087361,"d":"0.03"},{"v":0.333958174405141,"d":"0.33"},{"v":-1.58226066690893,"d":"-1.58"},1,1,"down","no"]
["ENSG00000235277","AF127577.3","ENST00000430391","NA","NA","NA","NA",null,0,{"v":0.036973,"d":"0.04"},"-inf","-inf",1,1,"down","no"]
["ENSG00000275426","AC253576.2","ENST00000618815","NA","NA","NA","NA",null,0,{"v":0.314647,"d":"0.31"},"-inf","-inf",1,1,"down","no"]
["ENSG00000165409","TSHR","ENST00000342443;ENST00000557096;ENST00000541158;ENST00000553763","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0004930(G-protein coupled receptor activity);GO:0007186(G-protein coupled receptor signaling pathway);GO:0005886(plasma membrane);GO:0004871(signal transducer activity);GO:0007165(signal transduction);GO:0004996(thyroid-stimulating hormone receptor activity);GO:0016500(protein-hormone receptor activity);GO:0007189(adenylate cyclase-activating G-protein coupled receptor signaling pathway);GO:0008344(adult locomotory behavior);GO:0030183(B cell differentiation);GO:0038194(thyroid-stimulating hormone signaling pathway);GO:0040012(regulation of locomotion);GO:0040018(positive regulation of multicellular organism growth);GO:0060119(inner ear receptor cell development);GO:0060122(inner ear receptor stereocilium organization);GO:0071542(dopaminergic neuron differentiation);GO:0090103(cochlea morphogenesis);GO:0005515(protein binding);GO:0007399(nervous system development);GO:0016323(basolateral plasma membrane);GO:0004872(receptor activity);GO:0009755(hormone-mediated signaling pathway);GO:0005887(integral component of plasma membrane);GO:0007267(cell-cell signaling);GO:0009986(cell surface);GO:0032403(protein complex binding);GO:0043235(receptor complex);GO:0008284(positive regulation of cell proliferation);GO:0030819(positive regulation of cAMP biosynthetic process);GO:0007166(cell surface receptor signaling pathway);GO:0045762(positive regulation of adenylate cyclase activity);GO:0007187(G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger);GO:0008528(G-protein coupled peptide receptor activity);GO:0007190(activation of adenylate cyclase activity);GO:1904588(cellular response to glycoprotein);GO:1905229(cellular response to thyrotropin-releasing hormone);GO:1905229(cellular response to thyrotropin-releasing hormone)","04024(cAMP signaling pathway);04080(Neuroactive ligand-receptor interaction);04923(Regulation of lipolysis in adipocyte);04918(Thyroid hormone synthesis);05320(Autoimmune thyroid disease);05320(Autoimmune thyroid disease)","K04249","NA","thyroid stimulating hormone receptor [Source:HGNC Symbol;Acc:HGNC:12373]",{"v":0.140061749739312,"d":"0.14"},{"v":0.0345180465762948,"d":"0.03"},{"v":4.05763835533785,"d":"4.06"},{"v":2.02064028791108,"d":"2.02"},1,1,"up","no"]
["MSTRG.13294","AL024508.1","ENST00000432477","NA","NA","NA","NA",null,{"v":0.100429,"d":"0.10"},{"v":0.117616,"d":"0.12"},{"v":0.853871922187458,"d":"0.85"},{"v":-0.227908408041924,"d":"-0.23"},1,1,"down","no"]
["ENSG00000203326","ZNF525","ENST00000497729;ENST00000474037;ENST00000601790;ENST00000475179;ENST00000593918;ENST00000600148;ENST00000467003","GO:0003676(nucleic acid binding);GO:0046872(metal ion binding);GO:0006355(regulation of transcription, DNA-templated);GO:0005622(intracellular);GO:0005622(intracellular)","NA","NA","NA","zinc finger protein 525 [Source:HGNC Symbol;Acc:HGNC:29423]",{"v":0.0796554970109829,"d":"0.08"},{"v":0.108779391074656,"d":"0.11"},{"v":0.732266435986159,"d":"0.73"},{"v":-0.449559424605038,"d":"-0.45"},1,1,"down","no"]
["ENSG00000131379","C3orf20","ENST00000253697","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005737(cytoplasm)","NA","NA","NA","chromosome 3 open reading frame 20 [Source:HGNC Symbol;Acc:HGNC:25320]",{"v":0.0167376282932417,"d":"0.02"},{"v":0.0419216964490263,"d":"0.04"},{"v":0.399259326577908,"d":"0.40"},{"v":-1.32460198593454,"d":"-1.32"},1,1,"down","no"]
["ENSG00000266088","AC004585.1","ENST00000577557;ENST00000578280","NA","NA","NA","NA",null,{"v":0.982780988313857,"d":"0.98"},{"v":0.439964952420701,"d":"0.44"},{"v":2.23377108314325,"d":"2.23"},{"v":1.15948134601111,"d":"1.16"},1,1,"up","no"]
["ENSG00000164107","HAND2","ENST00000359562","GO:0046983(protein dimerization activity);GO:0010667(negative regulation of cardiac muscle cell apoptotic process);GO:0010628(positive regulation of gene expression);GO:0010629(negative regulation of gene expression);GO:0070374(positive regulation of ERK1 and ERK2 cascade);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:1900745(positive regulation of p38MAPK cascade);GO:0010613(positive regulation of cardiac muscle hypertrophy);GO:0005634(nucleus);GO:0006366(transcription from RNA polymerase II promoter);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0007275(multicellular organism development);GO:0030154(cell differentiation);GO:0007507(heart development);GO:0043234(protein complex);GO:0042803(protein homodimerization activity);GO:0005667(transcription factor complex);GO:0003713(transcription coactivator activity);GO:0045893(positive regulation of transcription, DNA-templated);GO:0000790(nuclear chromatin);GO:0070888(E-box binding);GO:0044212(transcription regulatory region DNA binding);GO:0001525(angiogenesis);GO:0000977(RNA polymerase II regulatory region sequence-specific DNA binding);GO:0003357(noradrenergic neuron differentiation);GO:0001077(transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0007512(adult heart development);GO:0008134(transcription factor binding);GO:0034103(regulation of tissue remodeling);GO:2000679(positive regulation of transcription regulatory region DNA binding);GO:0003680(AT DNA binding);GO:0033613(activating transcription factor binding);GO:0048538(thymus development);GO:0043565(sequence-specific DNA binding);GO:0046982(protein heterodimerization activity);GO:0001701(in utero embryonic development);GO:0001947(heart looping);GO:0001967(suckling behavior);GO:0003007(heart morphogenesis);GO:0003219(cardiac right ventricle formation);GO:0003253(cardiac neural crest cell migration involved in outflow tract morphogenesis);GO:0003266(regulation of secondary heart field cardioblast proliferation);GO:0003278(apoptotic process involved in heart morphogenesis);GO:0010463(mesenchymal cell proliferation);GO:0014032(neural crest cell development);GO:0042475(odontogenesis of dentin-containing tooth);GO:0042733(embryonic digit morphogenesis);GO:0043066(negative regulation of apoptotic process);GO:0043392(negative regulation of DNA binding);GO:0043433(negative regulation of sequence-specific DNA binding transcription factor activity);GO:0043586(tongue development);GO:0045668(negative regulation of osteoblast differentiation);GO:0048485(sympathetic nervous system development);GO:0048935(peripheral nervous system neuron development);GO:0060021(palate development);GO:0060485(mesenchyme development);GO:0060536(cartilage morphogenesis);GO:0060982(coronary artery morphogenesis);GO:0061032(visceral serous pericardium development);GO:0061309(cardiac neural crest cell development involved in outflow tract morphogenesis);GO:0061325(cell proliferation involved in outflow tract morphogenesis);GO:0061371(determination of heart left/right asymmetry);GO:2000763(positive regulation of transcription from RNA polymerase II promoter involved in norepinephrine biosynthetic process);GO:2000764(positive regulation of semaphorin-plexin signaling pathway involved in outflow tract morphogenesis)","NA","NA","NA","heart and neural crest derivatives expressed 2 [Source:HGNC Symbol;Acc:HGNC:4808]",0,{"v":0.0345882643710081,"d":"0.03"},"-inf","-inf",1,1,"down","no"]
["ENSG00000257556","LINC02298","ENST00000548361;ENST00000548104;ENST00000546968","NA","NA","NA","NA","long intergenic non-protein coding RNA 2298 [Source:HGNC Symbol;Acc:HGNC:53216]",{"v":0.0871358054375531,"d":"0.09"},{"v":0.0108535819881054,"d":"0.01"},{"v":8.02829937001872,"d":"8.03"},{"v":3.00509441485557,"d":"3.01"},1,1,"up","no"]
["ENSG00000236480","PKMP1","ENST00000455804","NA","NA","NA","NA","pyruvate kinase, muscle pseudogene 1 [Source:HGNC Symbol;Acc:HGNC:44243]",{"v":0.02475,"d":"0.02"},{"v":0.021968,"d":"0.02"},{"v":1.12663874726875,"d":"1.13"},{"v":0.172024994594596,"d":"0.17"},1,1,"up","no"]
["ENSG00000255350","MTCO1P15","ENST00000529569","NA","NA","NA","NA","mitochondrially encoded cytochrome c oxidase I pseudogene 15 [Source:HGNC Symbol;Acc:HGNC:52017]",{"v":0.032561,"d":"0.03"},0,"inf","inf",1,1,"up","no"]
["ENSG00000269235","ZNF350-AS1","ENST00000600253;ENST00000595010","NA","NA","NA","NA","ZNF350 antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:48598]",{"v":0.0693536365422397,"d":"0.07"},{"v":0.0448173595284872,"d":"0.04"},{"v":1.54747261489505,"d":"1.55"},{"v":0.629913878774153,"d":"0.63"},1,1,"up","no"]
["ENSG00000189001","SBSN","ENST00000452271","GO:0005576(extracellular region);GO:0003674(molecular_function);GO:0008150(biological_process);GO:0070062(extracellular exosome);GO:0031012(extracellular matrix)","NA","NA","NA","suprabasin [Source:HGNC Symbol;Acc:HGNC:24950]",{"v":0.0240705991943605,"d":"0.02"},{"v":0.0374456570996979,"d":"0.04"},{"v":0.642814175493657,"d":"0.64"},{"v":-0.637526350863614,"d":"-0.64"},1,1,"down","no"]
["ENSG00000113211","PCDHB6","ENST00000231136","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0046872(metal ion binding);GO:0005509(calcium ion binding);GO:0007155(cell adhesion);GO:0007156(homophilic cell adhesion via plasma membrane adhesion molecules);GO:0005886(plasma membrane);GO:0005887(integral component of plasma membrane);GO:0042802(identical protein binding);GO:0007268(chemical synaptic transmission);GO:0007399(nervous system development);GO:0007416(synapse assembly);GO:0016339(calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules);GO:0009988(cell-cell recognition)","NA","NA","NA","protocadherin beta 6 [Source:HGNC Symbol;Acc:HGNC:8691]",{"v":0.078535,"d":"0.08"},{"v":0.013969,"d":"0.01"},{"v":5.62209177464385,"d":"5.62"},{"v":2.49110700436623,"d":"2.49"},1,1,"up","no"]
["MSTRG.6244","AC137932.1","ENST00000563087;ENST00000564394","NA","NA","NA","NA",null,{"v":0.216576750483559,"d":"0.22"},{"v":0.287494930367505,"d":"0.29"},{"v":0.753323720201635,"d":"0.75"},{"v":-0.408658138132796,"d":"-0.41"},1,1,"down","no"]
["MSTRG.7643","AC092068.3","ENST00000587894","NA","NA","NA","NA",null,{"v":0.075896,"d":"0.08"},0,"inf","inf",1,1,"up","no"]
["ENSG00000178395","CCDC185","ENST00000366875","GO:0005515(protein binding)","NA","NA","NA","coiled-coil domain containing 185 [Source:HGNC Symbol;Acc:HGNC:26654]",{"v":0.025025,"d":"0.03"},0,"inf","inf",1,1,"up","no"]
["ENSG00000264668","AC138696.1","ENST00000522452","GO:0003676(nucleic acid binding)","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000227551","USP17L12","ENST00000415041","GO:0005634(nucleus);GO:0016579(protein deubiquitination);GO:0016787(hydrolase activity);GO:0005783(endoplasmic reticulum);GO:0008233(peptidase activity);GO:0008234(cysteine-type peptidase activity);GO:0006508(proteolysis);GO:0006511(ubiquitin-dependent protein catabolic process);GO:0036459(thiol-dependent ubiquitinyl hydrolase activity)","NA","NA","NA","ubiquitin specific peptidase 17-like family member 12 [Source:HGNC Symbol;Acc:HGNC:44440]",{"v":0.047315,"d":"0.05"},0,"inf","inf",1,1,"up","no"]
["ENSG00000270445","AC145423.1","ENST00000605712","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000214584","PGGT1BP2","ENST00000398621","NA","NA","NA","NA","protein geranylgeranyltransferase type I subunit beta pseudogene 2 [Source:HGNC Symbol;Acc:HGNC:45112]",{"v":0.050002,"d":"0.05"},0,"inf","inf",1,1,"up","no"]
["ENSG00000170579","DLGAP1","ENST00000400150;ENST00000315677;ENST00000485480;ENST00000581527","GO:0016020(membrane);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0030054(cell junction);GO:0045202(synapse);GO:0045211(postsynaptic membrane);GO:0007268(chemical synaptic transmission);GO:0023052(signaling);GO:0005575(cellular_component);GO:0014069(postsynaptic density);GO:0019904(protein domain specific binding);GO:0006461(protein complex assembly);GO:0006461(protein complex assembly)","04724(Glutamatergic synapse);04724(Glutamatergic synapse)","K15008","NA","DLG associated protein 1 [Source:HGNC Symbol;Acc:HGNC:2905]",{"v":0.0175990859078143,"d":"0.02"},{"v":0.0354547319510986,"d":"0.04"},{"v":0.496381863275347,"d":"0.50"},{"v":-1.01047769142701,"d":"-1.01"},1,1,"down","no"]
["MSTRG.13399","AL035530.1","ENST00000446887","NA","NA","NA","NA",null,0,{"v":0.089081,"d":"0.09"},"-inf","-inf",1,1,"down","no"]
["MSTRG.9136","DARS-AS1","ENST00000399447;ENST00000444406;ENST00000601586;ENST00000595624;ENST00000598565;ENST00000597450;ENST00000595061;ENST00000625389;ENST00000446492;ENST00000444649;ENST00000594219;ENST00000615163","NA","NA","NA","NA","DARS antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:40170]",{"v":0.0589380729515687,"d":"0.06"},{"v":0.111206918519647,"d":"0.11"},{"v":0.529985667583767,"d":"0.53"},{"v":-0.915974749523618,"d":"-0.92"},1,1,"down","no"]
["ENSG00000263345","AC006435.2","ENST00000573007;ENST00000574290","NA","NA","NA","NA",null,{"v":0.796416996758509,"d":"0.80"},{"v":0.402487612641815,"d":"0.40"},{"v":1.97873666603316,"d":"1.98"},{"v":0.984579628612535,"d":"0.98"},1,1,"up","no"]
["ENSG00000242173","ARHGDIG","ENST00000477621","GO:0005737(cytoplasm);GO:0050790(regulation of catalytic activity);GO:0005094(Rho GDP-dissociation inhibitor activity);GO:0043547(positive regulation of GTPase activity);GO:0005515(protein binding);GO:0005096(GTPase activator activity);GO:0005829(cytosol);GO:0051056(regulation of small GTPase mediated signal transduction);GO:0005092(GDP-dissociation inhibitor activity);GO:0030695(GTPase regulator activity);GO:0032880(regulation of protein localization);GO:0016020(membrane);GO:0007266(Rho protein signal transduction);GO:0031410(cytoplasmic vesicle);GO:0007162(negative regulation of cell adhesion)","04962(Vasopressin-regulated water reabsorption);04722(Neurotrophin signaling pathway)","NA","NA","Rho GDP dissociation inhibitor gamma [Source:HGNC Symbol;Acc:HGNC:680]",0,{"v":0.00801428077398106,"d":"0.01"},"-inf","-inf",1,1,"down","no"]
["MSTRG.2606","AP003419.4","ENST00000616071","NA","NA","NA","NA",null,0,{"v":0.207675,"d":"0.21"},"-inf","-inf",1,1,"down","no"]
["ENSG00000260409","AC012414.5","ENST00000564214","NA","NA","NA","NA",null,{"v":0.032086,"d":"0.03"},{"v":0.126733,"d":"0.13"},{"v":0.253177941025621,"d":"0.25"},{"v":-1.98177638427319,"d":"-1.98"},1,1,"down","no"]
["ENSG00000156886","ITGAD","ENST00000389202","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0046872(metal ion binding);GO:0007155(cell adhesion);GO:0006955(immune response);GO:0007229(integrin-mediated signaling pathway);GO:0008305(integrin complex);GO:0005886(plasma membrane);GO:0009986(cell surface);GO:0030198(extracellular matrix organization);GO:0034113(heterotypic cell-cell adhesion)","04810(Regulation of actin cytoskeleton)","K06594","NA","integrin subunit alpha D [Source:HGNC Symbol;Acc:HGNC:6146]",{"v":0.0397354903649966,"d":"0.04"},{"v":0.101492055316255,"d":"0.10"},{"v":0.391513308516401,"d":"0.39"},{"v":-1.35286674572538,"d":"-1.35"},1,1,"down","no"]
["ENSG00000184530","C6orf58","ENST00000329722","GO:0005576(extracellular region);GO:0007275(multicellular organism development);GO:0005615(extracellular space);GO:0070062(extracellular exosome)","NA","NA","NA","chromosome 6 open reading frame 58 [Source:HGNC Symbol;Acc:HGNC:20960]",{"v":0.0156305882352941,"d":"0.02"},{"v":0.0298196078431373,"d":"0.03"},{"v":0.524171488690162,"d":"0.52"},{"v":-0.931889211736049,"d":"-0.93"},1,1,"down","no"]
["ENSG00000230581","ACTG1P14","ENST00000446382","NA","NA","NA","NA","actin gamma 1 pseudogene 14 [Source:HGNC Symbol;Acc:HGNC:49751]",{"v":0.079104,"d":"0.08"},0,"inf","inf",1,1,"up","no"]
["ENSG00000171723","GPHN","ENST00000478722;ENST00000556501;ENST00000555668;ENST00000459628;ENST00000543237","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0016740(transferase activity);GO:0006777(Mo-molybdopterin cofactor biosynthetic process);GO:0005886(plasma membrane);GO:0055114(oxidation-reduction process);GO:0005856(cytoskeleton);GO:0042995(cell projection);GO:0005515(protein binding);GO:0003824(catalytic activity);GO:0008152(metabolic process);GO:0030054(cell junction);GO:0045202(synapse);GO:0045211(postsynaptic membrane);GO:0030425(dendrite);GO:0032324(molybdopterin cofactor biosynthetic process);GO:0008940(nitrate reductase activity);GO:0043546(molybdopterin cofactor binding);GO:0061598(molybdopterin adenylyltransferase activity);GO:0061599(molybdopterin molybdotransferase activity);GO:0010038(response to metal ion);GO:0018315(molybdenum incorporation into molybdenum-molybdopterin complex);GO:0072579(glycine receptor clustering);GO:0097112(gamma-aminobutyric acid receptor clustering);GO:0097112(gamma-aminobutyric acid receptor clustering)","00790(Folate biosynthesis);04727(GABAergic synapse);04727(GABAergic synapse)","K15376","EC:2.10.1.1;EC:2.7.7.75","gephyrin [Source:HGNC Symbol;Acc:HGNC:15465]",{"v":0.431178591476611,"d":"0.43"},{"v":0.436392261361745,"d":"0.44"},{"v":0.988052790237698,"d":"0.99"},{"v":-0.0173399698997445,"d":"-0.02"},1,1,"down","no"]
["MSTRG.13089","GSTA4","ENST00000370960;ENST00000370963;ENST00000486559","GO:0005737(cytoplasm);GO:0016740(transferase activity);GO:0008152(metabolic process);GO:0042803(protein homodimerization activity);GO:0005515(protein binding);GO:0004364(glutathione transferase activity);GO:0042802(identical protein binding);GO:0006805(xenobiotic metabolic process);GO:0005829(cytosol);GO:1901687(glutathione derivative biosynthetic process);GO:0006749(glutathione metabolic process);GO:0006749(glutathione metabolic process)","00480(Glutathione metabolism);00980(Metabolism of xenobiotics by cytochrome P450);00982(Drug metabolism - cytochrome P450);00983(Drug metabolism - other enzymes);05200(Pathways in cancer);05204(Chemical carcinogenesis);05225(Hepatocellular carcinoma);05418(Fluid shear stress and atherosclerosis);01524(Platinum drug resistance);01524(Platinum drug resistance)","K00799","EC:2.5.1.18","glutathione S-transferase alpha 4 [Source:HGNC Symbol;Acc:HGNC:4629]",{"v":0.157869500689655,"d":"0.16"},0,"inf","inf",1,1,"up","no"]
["ENSG00000259604","AC015712.4","ENST00000558641","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000225868","AC016582.1","ENST00000592640","NA","NA","NA","NA",null,{"v":0.0515051038076152,"d":"0.05"},0,"inf","inf",1,1,"up","no"]
["MSTRG.6162","AC092139.3","ENST00000624764","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000127129","EDN2","ENST00000460255","GO:0005615(extracellular space);GO:0008284(positive regulation of cell proliferation);GO:0010460(positive regulation of heart rate);GO:0005622(intracellular);GO:0005623(cell);GO:0007204(positive regulation of cytosolic calcium ion concentration);GO:0005576(extracellular region);GO:0042310(vasoconstriction);GO:0050880(regulation of blood vessel size);GO:0019229(regulation of vasoconstriction);GO:0019221(cytokine-mediated signaling pathway);GO:0019722(calcium-mediated signaling);GO:0007166(cell surface receptor signaling pathway);GO:0005179(hormone activity);GO:0030593(neutrophil chemotaxis);GO:0002690(positive regulation of leukocyte chemotaxis);GO:0031708(endothelin B receptor binding);GO:0001516(prostaglandin biosynthetic process);GO:0003100(regulation of systemic arterial blood pressure by endothelin);GO:0014824(artery smooth muscle contraction);GO:0014826(vein smooth muscle contraction);GO:0048016(inositol phosphate-mediated signaling);GO:0060585(positive regulation of prostaglandin-endoperoxide synthase activity);GO:0048246(macrophage chemotaxis);GO:0001659(temperature homeostasis);GO:0003058(hormonal regulation of the force of heart contraction);GO:0003099(positive regulation of the force of heart contraction by chemical signal);GO:0042116(macrophage activation);GO:0045987(positive regulation of smooth muscle contraction);GO:0048286(lung alveolus development);GO:0097009(energy homeostasis)","04080(Neuroactive ligand-receptor interaction);04270(Vascular smooth muscle contraction)","NA","NA","endothelin 2 [Source:HGNC Symbol;Acc:HGNC:3177]",0,{"v":0.00870958206223307,"d":"0.01"},"-inf","-inf",1,1,"down","no"]
["ENSG00000175189","INHBC","ENST00000309668","GO:0008083(growth factor activity);GO:0005576(extracellular region);GO:0005179(hormone activity);GO:0005615(extracellular space);GO:0070062(extracellular exosome);GO:0060395(SMAD protein signal transduction);GO:0005125(cytokine activity);GO:0010862(positive regulation of pathway-restricted SMAD protein phosphorylation);GO:0042981(regulation of apoptotic process);GO:0043408(regulation of MAPK cascade);GO:0048468(cell development);GO:0005160(transforming growth factor beta receptor binding)","04350(TGF-beta signaling pathway);04060(Cytokine-cytokine receptor interaction);04550(Signaling pathways regulating pluripotency of stem cells)","K04667","NA","inhibin beta C subunit [Source:HGNC Symbol;Acc:HGNC:6068]",{"v":0.076897,"d":"0.08"},{"v":0.080772,"d":"0.08"},{"v":0.952025454365374,"d":"0.95"},{"v":-0.0709279474090188,"d":"-0.07"},1,1,"down","no"]
["ENSG00000262904","TMPOP2","ENST00000575258","NA","NA","NA","NA","thymopoietin pseudogene 2 [Source:HGNC Symbol;Acc:HGNC:50860]",0,{"v":0.036089,"d":"0.04"},"-inf","-inf",1,1,"down","no"]
["ENSG00000229266","POM121L8P","ENST00000417732","NA","NA","NA","NA","POM121 transmembrane nucleoporin like 8, pseudogene [Source:HGNC Symbol;Acc:HGNC:35446]",{"v":0.040126,"d":"0.04"},{"v":0.005817,"d":"0.01"},{"v":6.89805741791301,"d":"6.90"},{"v":2.78619013752501,"d":"2.79"},1,1,"up","no"]
["ENSG00000230290","ARMC2-AS1","ENST00000426737","NA","NA","NA","NA","ARMC2 antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:41008]",{"v":0.367157,"d":"0.37"},0,"inf","inf",1,1,"up","no"]
["ENSG00000178795","GDPD4","ENST00000315938","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0046872(metal ion binding);GO:0016787(hydrolase activity);GO:0006629(lipid metabolic process);GO:0008081(phosphoric diester hydrolase activity);GO:0008889(glycerophosphodiester phosphodiesterase activity)","NA","NA","NA","glycerophosphodiester phosphodiesterase domain containing 4 [Source:HGNC Symbol;Acc:HGNC:24849]",{"v":0.0250415812421581,"d":"0.03"},{"v":7.9192004391468E-3,"d":"0.01"},{"v":3.16213504565065,"d":"3.16"},{"v":1.66089898234844,"d":"1.66"},1,1,"up","no"]
["MSTRG.4209","TRAV29DV5","ENST00000390458","NA","NA","NA","NA","T-cell receptor alpha variable 29/delta variable 5 (gene/pseudogene) [Source:HGNC Symbol;Acc:HGNC:12127]",{"v":0.415798,"d":"0.42"},{"v":0.632314,"d":"0.63"},{"v":0.657581518043251,"d":"0.66"},{"v":-0.604758343620277,"d":"-0.60"},1,1,"down","no"]
["ENSG00000240303","ACAD11","ENST00000481970;ENST00000510100;ENST00000485198;ENST00000264990;ENST00000496418","GO:0005634(nucleus);GO:0016491(oxidoreductase activity);GO:0050660(flavin adenine dinucleotide binding);GO:0055114(oxidation-reduction process);GO:0016627(oxidoreductase activity, acting on the CH-CH group of donors);GO:0008152(metabolic process);GO:0005739(mitochondrion);GO:0005777(peroxisome);GO:0031966(mitochondrial membrane);GO:0005743(mitochondrial inner membrane);GO:0006635(fatty acid beta-oxidation);GO:0003995(acyl-CoA dehydrogenase activity);GO:0033539(fatty acid beta-oxidation using acyl-CoA dehydrogenase);GO:0004466(long-chain-acyl-CoA dehydrogenase activity);GO:0017099(very-long-chain-acyl-CoA dehydrogenase activity);GO:0070991(medium-chain-acyl-CoA dehydrogenase activity);GO:0070991(medium-chain-acyl-CoA dehydrogenase activity)","NA","NA","NA","acyl-CoA dehydrogenase family member 11 [Source:HGNC Symbol;Acc:HGNC:30211]",{"v":0.0856114695100458,"d":"0.09"},{"v":0.428410841381741,"d":"0.43"},{"v":0.199834974376292,"d":"0.20"},{"v":-2.32311899452206,"d":"-2.32"},1,1,"down","no"]
["ENSG00000176007","FAM220BP","ENST00000377689","NA","NA","NA","NA","family with sequence similarity 220 member B, pseudogene [Source:HGNC Symbol;Acc:HGNC:23678]",{"v":0.113807,"d":"0.11"},{"v":0.077344,"d":"0.08"},{"v":1.47143928423666,"d":"1.47"},{"v":0.55722801381222,"d":"0.56"},1,1,"up","no"]
["ENSG00000102466","FGF14","ENST00000376143;ENST00000376131","GO:0005634(nucleus);GO:0008083(growth factor activity);GO:0005576(extracellular region);GO:0007399(nervous system development);GO:0005515(protein binding);GO:0007165(signal transduction);GO:0007267(cell-cell signaling);GO:0048167(regulation of synaptic plasticity);GO:0060078(regulation of postsynaptic membrane potential);GO:1901843(positive regulation of high voltage-gated calcium channel activity);GO:1903421(regulation of synaptic vesicle recycling);GO:1903421(regulation of synaptic vesicle recycling)","NA","NA","NA","fibroblast growth factor 14 [Source:HGNC Symbol;Acc:HGNC:3671]",{"v":0.00693608285485864,"d":"0.01"},{"v":6.63152889018097E-3,"d":"0.01"},{"v":1.04592515085452,"d":"1.05"},{"v":0.0647796122399854,"d":"0.06"},1,1,"up","no"]
["ENSG00000170608","FOXA3","ENST00000302177","GO:0005634(nucleus);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0043565(sequence-specific DNA binding);GO:0008134(transcription factor binding);GO:0019904(protein domain specific binding);GO:0005654(nucleoplasm);GO:0006351(transcription, DNA-templated);GO:0016569(covalent chromatin modification);GO:0001678(cellular glucose homeostasis);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0007283(spermatogenesis);GO:0009267(cellular response to starvation);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0015629(actin cytoskeleton);GO:0007275(multicellular organism development);GO:0030154(cell differentiation);GO:0000981(RNA polymerase II transcription factor activity, sequence-specific DNA binding);GO:0009653(anatomical structure morphogenesis);GO:0044212(transcription regulatory region DNA binding)","04950(Maturity onset diabetes of the young)","K08038","NA","forkhead box A3 [Source:HGNC Symbol;Acc:HGNC:5023]",{"v":0.0249350912408759,"d":"0.02"},{"v":0.041627447080292,"d":"0.04"},{"v":0.599006016217629,"d":"0.60"},{"v":-0.739357601850344,"d":"-0.74"},1,1,"down","no"]
["ENSG00000160838","LRRC71","ENST00000472465;ENST00000337428","NA","NA","NA","NA","leucine rich repeat containing 71 [Source:HGNC Symbol;Acc:HGNC:26556]",{"v":0.0107450889395667,"d":"0.01"},{"v":0.0294222291904219,"d":"0.03"},{"v":0.365203087435151,"d":"0.37"},{"v":-1.45322913293721,"d":"-1.45"},1,1,"down","no"]
["ENSG00000101405","OXT","ENST00000217386","GO:0005576(extracellular region);GO:0005179(hormone activity);GO:0007165(signal transduction);GO:0005184(neuropeptide hormone activity);GO:0005185(neurohypophyseal hormone activity);GO:0031855(oxytocin receptor binding);GO:0001975(response to amphetamine);GO:0002027(regulation of heart rate);GO:0002125(maternal aggressive behavior);GO:0007204(positive regulation of cytosolic calcium ion concentration);GO:0007507(heart development);GO:0007565(female pregnancy);GO:0007613(memory);GO:0007625(grooming behavior);GO:0009744(response to sucrose);GO:0010701(positive regulation of norepinephrine secretion);GO:0014070(response to organic cyclic compound);GO:0014823(response to activity);GO:0030431(sleep);GO:0032094(response to food);GO:0032308(positive regulation of prostaglandin secretion);GO:0032355(response to estradiol);GO:0032526(response to retinoic acid);GO:0032570(response to progesterone);GO:0034695(response to prostaglandin E);GO:0035176(social behavior);GO:0035811(negative regulation of urine volume);GO:0035815(positive regulation of renal sodium excretion);GO:0042220(response to cocaine);GO:0042538(hyperosmotic salinity response);GO:0042711(maternal behavior);GO:0042713(sperm ejaculation);GO:0042755(eating behavior);GO:0042756(drinking behavior);GO:0043434(response to peptide hormone);GO:0044058(regulation of digestive system process);GO:0045472(response to ether);GO:0045776(negative regulation of blood pressure);GO:0045777(positive regulation of blood pressure);GO:0045778(positive regulation of ossification);GO:0045925(positive regulation of female receptivity);GO:0048545(response to steroid hormone);GO:0050806(positive regulation of synaptic transmission);GO:0051384(response to glucocorticoid);GO:0051591(response to cAMP);GO:0051602(response to electrical stimulus);GO:0051930(regulation of sensory perception of pain);GO:0051965(positive regulation of synapse assembly);GO:0060179(male mating behavior);GO:0060406(positive regulation of penile erection);GO:0060450(positive regulation of hindgut contraction);GO:0060455(negative regulation of gastric acid secretion);GO:0070474(positive regulation of uterine smooth muscle contraction);GO:0005615(extracellular space);GO:0005737(cytoplasm);GO:0030141(secretory granule);GO:0043195(terminal bouton)","04921(Oxytocin signaling pathway)","K05243","NA","oxytocin/neurophysin I prepropeptide [Source:HGNC Symbol;Acc:HGNC:8528]",{"v":0.092183,"d":"0.09"},0,"inf","inf",1,1,"up","no"]
["ENSG00000196747","HIST1H2AI","ENST00000358739","GO:0005634(nucleus);GO:0003677(DNA binding);GO:0046982(protein heterodimerization activity);GO:0000786(nucleosome);GO:0005694(chromosome);GO:0005515(protein binding);GO:0000790(nuclear chromatin);GO:0008150(biological_process);GO:0070062(extracellular exosome);GO:0019899(enzyme binding);GO:0006342(chromatin silencing)","04217(Necroptosis);05322(Systemic lupus erythematosus);05034(Alcoholism)","K11251","NA","histone cluster 1 H2A family member i [Source:HGNC Symbol;Acc:HGNC:4725]",{"v":0.799928,"d":"0.80"},0,"inf","inf",1,1,"up","no"]
["ENSG00000256001","AC079949.1","ENST00000535022;ENST00000541419","NA","NA","NA","NA",null,0,{"v":0.059215349025974,"d":"0.06"},"-inf","-inf",1,1,"down","no"]
["MSTRG.9008","AC016738.1","ENST00000452364","NA","NA","NA","NA",null,0,{"v":0.005324,"d":"0.01"},"-inf","-inf",1,1,"down","no"]
["ENSG00000135931","ARMC9","ENST00000611582;ENST00000486787","GO:0070062(extracellular exosome);GO:0070062(extracellular exosome)","NA","NA","NA","armadillo repeat containing 9 [Source:HGNC Symbol;Acc:HGNC:20730]",{"v":0.0181592399337543,"d":"0.02"},{"v":0.0419934286305765,"d":"0.04"},{"v":0.432430514152686,"d":"0.43"},{"v":-1.20945976546996,"d":"-1.21"},1,1,"down","no"]
["MSTRG.9118","AC073869.2","ENST00000417338","NA","NA","NA","NA",null,0,{"v":0.035574,"d":"0.04"},"-inf","-inf",1,1,"down","no"]
["ENSG00000135480","KRT7","ENST00000549638;ENST00000331817;ENST00000548088;ENST00000548657","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005198(structural molecule activity);GO:0005515(protein binding);GO:0005882(intermediate filament);GO:0045095(keratin filament);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0031424(keratinization);GO:0016032(viral process);GO:0070268(cornification);GO:0070268(cornification)","NA","NA","NA","keratin 7 [Source:HGNC Symbol;Acc:HGNC:6445]",{"v":0.107932917175666,"d":"0.11"},{"v":0.115592224529685,"d":"0.12"},{"v":0.933738559101335,"d":"0.93"},{"v":-0.098909433910669,"d":"-0.10"},1,1,"down","no"]
["ENSG00000273598","AC211486.3","ENST00000412694","NA","NA","NA","NA",null,{"v":0.174539,"d":"0.17"},{"v":0.235757,"d":"0.24"},{"v":0.74033432729463,"d":"0.74"},{"v":-0.43375117089515,"d":"-0.43"},1,1,"down","no"]
["ENSG00000271040","AL390955.2","ENST00000603032","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000018869","ZNF582","ENST00000593145;ENST00000586929;ENST00000589143;ENST00000619584;ENST00000587778;ENST00000301310","GO:0003676(nucleic acid binding);GO:0006355(regulation of transcription, DNA-templated);GO:0005622(intracellular);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0003677(DNA binding)","NA","NA","NA","zinc finger protein 582 [Source:HGNC Symbol;Acc:HGNC:26421]",{"v":0.210828207462687,"d":"0.21"},{"v":0.118266917014925,"d":"0.12"},{"v":1.78264736059773,"d":"1.78"},{"v":0.834021340409025,"d":"0.83"},1,1,"up","no"]
["ENSG00000254876","AL590705.5","ENST00000375204;ENST00000527128","NA","NA","NA","NA",null,{"v":0.0840842883004593,"d":"0.08"},{"v":0.0935616711699541,"d":"0.09"},{"v":0.898704429378146,"d":"0.90"},{"v":-0.154081382244451,"d":"-0.15"},1,1,"down","no"]
["ENSG00000272979","AC093388.1","ENST00000609166","NA","NA","NA","NA",null,0,{"v":0.293549,"d":"0.29"},"-inf","-inf",1,1,"down","no"]
["MSTRG.4448","AL139021.2","ENST00000556390","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["MSTRG.15438","AL121601.1","ENST00000426367","NA","NA","NA","NA",null,0,{"v":0.154925,"d":"0.15"},"-inf","-inf",1,1,"down","no"]
["ENSG00000243629","LINC00880","ENST00000471357","NA","NA","NA","NA","long intergenic non-protein coding RNA 880 [Source:HGNC Symbol;Acc:HGNC:27948]",0,0,1,0,1,1,"no","no"]
["ENSG00000234558","API5P1","ENST00000424316","NA","NA","NA","NA","apoptosis inhibitor 5 pseudogene 1 [Source:HGNC Symbol;Acc:HGNC:595]",{"v":0.407755,"d":"0.41"},{"v":0.279937,"d":"0.28"},{"v":1.45659559115087,"d":"1.46"},{"v":0.542600383492663,"d":"0.54"},1,1,"up","no"]
["ENSG00000250654","AC023794.3","ENST00000505259;ENST00000607809;ENST00000510754;ENST00000514503","NA","NA","NA","NA",null,{"v":0.233055353956835,"d":"0.23"},{"v":0.0989063136690648,"d":"0.10"},{"v":2.3563243367519,"d":"2.36"},{"v":1.23653813289446,"d":"1.24"},1,1,"up","no"]
["ENSG00000267325","LINC01415","ENST00000588134;ENST00000587320","NA","NA","NA","NA","long intergenic non-protein coding RNA 1415 [Source:HGNC Symbol;Acc:HGNC:50709]",0,0,1,0,1,1,"no","no"]
["ENSG00000204655","MOG","ENST00000469353;ENST00000376894","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0007155(cell adhesion);GO:0005886(plasma membrane);GO:0046718(viral entry into host cell);GO:0016032(viral process);GO:0007417(central nervous system development);GO:0001618(virus receptor activity);GO:0001618(virus receptor activity)","NA","NA","NA","myelin oligodendrocyte glycoprotein [Source:HGNC Symbol;Acc:HGNC:7197]",0,{"v":0.0428022728410513,"d":"0.04"},"-inf","-inf",1,1,"down","no"]
["MSTRG.856","AC239860.1","ENST00000444680","NA","NA","NA","NA",null,{"v":0.075012,"d":"0.08"},{"v":0.024778,"d":"0.02"},{"v":3.02736298329163,"d":"3.03"},{"v":1.59806166584895,"d":"1.60"},1,1,"up","no"]
["MSTRG.8059","AC008738.3","ENST00000589932","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["MSTRG.12553","OR1X1P","ENST00000606159","NA","NA","NA","NA","olfactory receptor family 1 subfamily X member 1 pseudogene [Source:HGNC Symbol;Acc:HGNC:15062]",0,{"v":0.09801,"d":"0.10"},"-inf","-inf",1,1,"down","no"]
["ENSG00000259583","AC015712.2","ENST00000560068;ENST00000560351","NA","NA","NA","NA",null,{"v":0.0227038536513545,"d":"0.02"},{"v":0.0121136548881037,"d":"0.01"},{"v":1.8742364596874,"d":"1.87"},{"v":0.906302979516777,"d":"0.91"},1,1,"up","no"]
["ENSG00000204887","KRTAP1-4","ENST00000377747","GO:0005882(intermediate filament);GO:0045095(keratin filament);GO:0005829(cytosol);GO:0031424(keratinization)","NA","NA","NA","keratin associated protein 1-4 [Source:HGNC Symbol;Acc:HGNC:18904]",{"v":0.251131,"d":"0.25"},0,"inf","inf",1,1,"up","no"]
["MSTRG.2398","AP001350.1","ENST00000601906","NA","NA","NA","NA",null,{"v":0.133564,"d":"0.13"},0,"inf","inf",1,1,"up","no"]
["MSTRG.1347","AC244034.1","ENST00000428027","NA","NA","NA","NA",null,{"v":0.056032,"d":"0.06"},0,"inf","inf",1,1,"up","no"]
["MSTRG.5904","AC012186.3","ENST00000623850","NA","NA","NA","NA",null,0,{"v":0.09407,"d":"0.09"},"-inf","-inf",1,1,"down","no"]
["MSTRG.5117","ALDH1A2","ENST00000558946;ENST00000558239;ENST00000560122;ENST00000559579;ENST00000558504;ENST00000249750;ENST00000560863;ENST00000557967","GO:0005737(cytoplasm);GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0008152(metabolic process);GO:0005829(cytosol);GO:0008285(negative regulation of cell proliferation);GO:0004029(aldehyde dehydrogenase (NAD) activity);GO:0042573(retinoic acid metabolic process);GO:0001758(retinal dehydrogenase activity);GO:0042572(retinol metabolic process);GO:0004028(3-chloroallyl aldehyde dehydrogenase activity);GO:0016918(retinal binding);GO:0006776(vitamin A metabolic process);GO:0021915(neural tube development);GO:0034097(response to cytokine);GO:0001568(blood vessel development);GO:0001822(kidney development);GO:0001889(liver development);GO:0001936(regulation of endothelial cell proliferation);GO:0002138(retinoic acid biosynthetic process);GO:0003007(heart morphogenesis);GO:0007494(midgut development);GO:0008284(positive regulation of cell proliferation);GO:0009855(determination of bilateral symmetry);GO:0009952(anterior/posterior pattern specification);GO:0009954(proximal/distal pattern formation);GO:0010628(positive regulation of gene expression);GO:0014032(neural crest cell development);GO:0016331(morphogenesis of embryonic epithelium);GO:0021983(pituitary gland development);GO:0030182(neuron differentiation);GO:0030324(lung development);GO:0030326(embryonic limb morphogenesis);GO:0030900(forebrain development);GO:0030902(hindbrain development);GO:0031016(pancreas development);GO:0031076(embryonic camera-type eye development);GO:0032355(response to estradiol);GO:0033189(response to vitamin A);GO:0035115(embryonic forelimb morphogenesis);GO:0035799(ureter maturation);GO:0042574(retinal metabolic process);GO:0042904(9-cis-retinoic acid biosynthetic process);GO:0043010(camera-type eye development);GO:0043065(positive regulation of apoptotic process);GO:0048384(retinoic acid receptor signaling pathway);GO:0048566(embryonic digestive tract development);GO:0048738(cardiac muscle tissue development);GO:0060324(face development);GO:0071300(cellular response to retinoic acid);GO:0048471(perinuclear region of cytoplasm);GO:0048471(perinuclear region of cytoplasm)","00830(Retinol metabolism);00830(Retinol metabolism)","K07249","EC:1.2.1.36","aldehyde dehydrogenase 1 family member A2 [Source:HGNC Symbol;Acc:HGNC:15472]",{"v":0.0448861695662259,"d":"0.04"},{"v":0.062248135467409,"d":"0.06"},{"v":0.721084563082645,"d":"0.72"},{"v":-0.471759637659584,"d":"-0.47"},1,1,"down","no"]
["ENSG00000144130","NT5DC4","ENST00000327581;ENST00000484666;ENST00000497526;ENST00000491170","GO:0046872(metal ion binding);GO:0016787(hydrolase activity);GO:0016311(dephosphorylation);GO:0008253(5'-nucleotidase activity);GO:0008253(5'-nucleotidase activity)","NA","NA","NA","5'-nucleotidase domain containing 4 [Source:HGNC Symbol;Acc:HGNC:27678]",{"v":0.046526304852071,"d":"0.05"},{"v":0.209331644733728,"d":"0.21"},{"v":0.22226121096623,"d":"0.22"},{"v":-2.16967190374024,"d":"-2.17"},1,1,"down","no"]
["MSTRG.6753","AC006449.6","ENST00000612330","NA","NA","NA","NA",null,{"v":0.675584,"d":"0.68"},{"v":0.226198,"d":"0.23"},{"v":2.98669307420932,"d":"2.99"},{"v":1.57854898754244,"d":"1.58"},1,1,"up","no"]
["ENSG00000275489","C17orf98","ENST00000614158","NA","NA","NA","NA","chromosome 17 open reading frame 98 [Source:HGNC Symbol;Acc:HGNC:34492]",0,{"v":0.095821,"d":"0.10"},"-inf","-inf",1,1,"down","no"]
["MSTRG.9141","MTND6P11","ENST00000431890","NA","NA","NA","NA","mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 6 pseudogene 11 [Source:HGNC Symbol;Acc:HGNC:39474]",{"v":0.166019,"d":"0.17"},{"v":0.083439,"d":"0.08"},{"v":1.98970505399154,"d":"1.99"},{"v":0.9925545872108,"d":"0.99"},1,1,"up","no"]
["ENSG00000197358","BNIP3P1","ENST00000550043","NA","NA","NA","NA","BCL2 interacting protein 3 pseudogene 1 [Source:HGNC Symbol;Acc:HGNC:19922]",0,{"v":0.026194,"d":"0.03"},"-inf","-inf",1,1,"down","no"]
["ENSG00000203785","SPRR2E","ENST00000368751","GO:0005737(cytoplasm);GO:0005515(protein binding);GO:0031424(keratinization);GO:0005829(cytosol);GO:0001533(cornified envelope);GO:0008544(epidermis development);GO:0030216(keratinocyte differentiation);GO:0005198(structural molecule activity);GO:0070268(cornification);GO:0030280(structural constituent of epidermis);GO:0018149(peptide cross-linking);GO:0098773(skin epidermis development)","NA","NA","NA","small proline rich protein 2E [Source:HGNC Symbol;Acc:HGNC:11265]",0,{"v":0.0107740817438692,"d":"0.01"},"-inf","-inf",1,1,"down","no"]
["ENSG00000268970","AC022150.2","ENST00000596451","NA","NA","NA","NA",null,{"v":0.914388,"d":"0.91"},{"v":1.137628,"d":"1.14"},{"v":0.803767136533208,"d":"0.80"},{"v":-0.315150503469575,"d":"-0.32"},1,1,"down","no"]
["ENSG00000264635","AP001020.2","ENST00000581712","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000124615","MOCS1","ENST00000373186;ENST00000373188;ENST00000373181","GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0003824(catalytic activity);GO:0016829(lyase activity);GO:0005525(GTP binding);GO:0006777(Mo-molybdopterin cofactor biosynthetic process);GO:0019008(molybdopterin synthase complex);GO:0051536(iron-sulfur cluster binding);GO:0051539(4 iron, 4 sulfur cluster binding);GO:0005829(cytosol);GO:0032324(molybdopterin cofactor biosynthetic process);GO:0061798(GTP 3',8'-cyclase activity);GO:0061799(cyclic pyranopterin monophosphate synthase activity);GO:0061799(cyclic pyranopterin monophosphate synthase activity)","00790(Folate biosynthesis);00790(Folate biosynthesis)","K20967","EC:4.1.99.22;EC:4.6.1.17","molybdenum cofactor synthesis 1 [Source:HGNC Symbol;Acc:HGNC:7190]",{"v":0.115043611905682,"d":"0.12"},{"v":0.144848948202551,"d":"0.14"},{"v":0.794231600113586,"d":"0.79"},{"v":-0.332368332337474,"d":"-0.33"},1,1,"down","no"]
["ENSG00000259820","AC083843.2","ENST00000568248","NA","NA","NA","NA",null,0,{"v":0.192355,"d":"0.19"},"-inf","-inf",1,1,"down","no"]
["MSTRG.14577","AC022973.3","ENST00000521014","NA","NA","NA","NA",null,{"v":0.079068,"d":"0.08"},0,"inf","inf",1,1,"up","no"]
["ENSG00000232000","CLCN3P1","ENST00000423965;ENST00000609203","NA","NA","NA","NA","chloride voltage-gated channel 3 pseudogene 1 [Source:HGNC Symbol;Acc:HGNC:49775]",{"v":0.0152814413128791,"d":"0.02"},{"v":0.0251746503745986,"d":"0.03"},{"v":0.607017022500467,"d":"0.61"},{"v":-0.720191120527227,"d":"-0.72"},1,1,"down","no"]
["ENSG00000204624","DISP3","ENST00000294484","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0006629(lipid metabolic process);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0008202(steroid metabolic process);GO:0030154(cell differentiation);GO:0030659(cytoplasmic vesicle membrane);GO:0031410(cytoplasmic vesicle);GO:0008203(cholesterol metabolic process);GO:0007224(smoothened signaling pathway);GO:0003674(molecular_function);GO:2000179(positive regulation of neural precursor cell proliferation);GO:0031965(nuclear membrane);GO:0045665(negative regulation of neuron differentiation);GO:0042632(cholesterol homeostasis);GO:0032368(regulation of lipid transport);GO:0045834(positive regulation of lipid metabolic process)","NA","NA","NA","dispatched RND transporter family member 3 [Source:HGNC Symbol;Acc:HGNC:29251]",{"v":0.084379073591664,"d":"0.08"},{"v":0.0506853508629111,"d":"0.05"},{"v":1.66476254292654,"d":"1.66"},{"v":0.735316409985228,"d":"0.74"},1,1,"up","no"]
["ENSG00000127377","CRYGN","ENST00000462809;ENST00000337323;ENST00000476631;ENST00000491928;ENST00000478106","NA","NA","NA","NA","crystallin gamma N [Source:HGNC Symbol;Acc:HGNC:20458]",{"v":0.148504874447717,"d":"0.15"},{"v":0.0558583026509573,"d":"0.06"},{"v":2.65859983923396,"d":"2.66"},{"v":1.41066664541761,"d":"1.41"},1,1,"up","no"]
["ENSG00000279243","AP000769.3","ENST00000622944","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000228043","AC114763.1","ENST00000414911;ENST00000431985","NA","NA","NA","NA",null,{"v":0.0708152140137091,"d":"0.07"},{"v":0.0655572277227723,"d":"0.07"},{"v":1.08020452471193,"d":"1.08"},{"v":0.111304496511033,"d":"0.11"},1,1,"up","no"]
["MSTRG.3796","AC063943.1","ENST00000465434","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000156096","UGT2B4","ENST00000305107","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016740(transferase activity);GO:0016757(transferase activity, transferring glycosyl groups);GO:0008152(metabolic process);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0016758(transferase activity, transferring hexosyl groups);GO:0006805(xenobiotic metabolic process);GO:0015020(glucuronosyltransferase activity);GO:0043231(intracellular membrane-bounded organelle);GO:0031090(organelle membrane);GO:0006711(estrogen catabolic process);GO:0052695(cellular glucuronidation)","00040(Pentose and glucuronate interconversions);00053(Ascorbate and aldarate metabolism);00140(Steroid hormone biosynthesis);00830(Retinol metabolism);00860(Porphyrin and chlorophyll metabolism);00980(Metabolism of xenobiotics by cytochrome P450);00982(Drug metabolism - cytochrome P450);00983(Drug metabolism - other enzymes);04976(Bile secretion);05204(Chemical carcinogenesis)","K00699","EC:2.4.1.17","UDP glucuronosyltransferase family 2 member B4 [Source:HGNC Symbol;Acc:HGNC:12553]",{"v":0.0352970003990423,"d":"0.04"},0,"inf","inf",1,1,"up","no"]
["ENSG00000260918","AC107398.3","ENST00000562284","NA","NA","NA","NA",null,{"v":0.007343,"d":"0.01"},0,"inf","inf",1,1,"up","no"]
["ENSG00000237934","AL590729.1","ENST00000427046","NA","NA","NA","NA",null,0,{"v":0.064181,"d":"0.06"},"-inf","-inf",1,1,"down","no"]
["ENSG00000279177","FP236241.2","ENST00000624906","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000138308","PLA2G12B","ENST00000373032","GO:0046872(metal ion binding);GO:0005509(calcium ion binding);GO:0005576(extracellular region);GO:0004623(phospholipase A2 activity);GO:0006644(phospholipid metabolic process);GO:0016042(lipid catabolic process);GO:0050482(arachidonic acid secretion)","00564(Glycerophospholipid metabolism);00565(Ether lipid metabolism);00590(Arachidonic acid metabolism);00591(Linoleic acid metabolism);00592(alpha-Linolenic acid metabolism);04014(Ras signaling pathway);04270(Vascular smooth muscle contraction);04972(Pancreatic secretion);04975(Fat digestion and absorption)","K01047","EC:3.1.1.4","phospholipase A2 group XIIB [Source:HGNC Symbol;Acc:HGNC:18555]",{"v":0.058177,"d":"0.06"},0,"inf","inf",1,1,"up","no"]
["ENSG00000100312","ACR","ENST00000216139","GO:0005634(nucleus);GO:0016787(hydrolase activity);GO:0003677(DNA binding);GO:0008270(zinc ion binding);GO:0008233(peptidase activity);GO:0006508(proteolysis);GO:0004252(serine-type endopeptidase activity);GO:0008236(serine-type peptidase activity);GO:0005576(extracellular region);GO:0005515(protein binding);GO:0042806(fucose binding);GO:0007338(single fertilization);GO:0043234(protein complex);GO:0001669(acrosomal vesicle);GO:0005507(copper ion binding);GO:0008144(drug binding);GO:0007340(acrosome reaction);GO:0005537(mannose binding);GO:0007190(activation of adenylate cyclase activity);GO:0002020(protease binding);GO:0004040(amidase activity);GO:0002077(acrosome matrix dispersal);GO:0007339(binding of sperm to zona pellucida);GO:0048545(response to steroid hormone);GO:0005798(Golgi-associated vesicle);GO:0043159(acrosomal matrix)","NA","NA","NA","acrosin [Source:HGNC Symbol;Acc:HGNC:126]",{"v":0.0594649762020398,"d":"0.06"},{"v":0.0200905347255949,"d":"0.02"},{"v":2.95985034814841,"d":"2.96"},{"v":1.5655242341508,"d":"1.57"},1,1,"up","no"]
["ENSG00000103528","SYT17","ENST00000562034;ENST00000568433;ENST00000355377;ENST00000562274;ENST00000568115;ENST00000570264","GO:0016020(membrane);GO:0006887(exocytosis);GO:0005515(protein binding);GO:0030154(cell differentiation);GO:0098793(presynapse);GO:0005886(plasma membrane);GO:0005509(calcium ion binding);GO:0005544(calcium-dependent phospholipid binding);GO:0019905(syntaxin binding);GO:0030276(clathrin binding);GO:0006906(vesicle fusion);GO:0017158(regulation of calcium ion-dependent exocytosis);GO:0048791(calcium ion-regulated exocytosis of neurotransmitter);GO:1903861(positive regulation of dendrite extension);GO:0005802(trans-Golgi network);GO:0046928(regulation of neurotransmitter secretion);GO:0060291(long-term synaptic potentiation);GO:0060291(long-term synaptic potentiation)","NA","NA","NA","synaptotagmin 17 [Source:HGNC Symbol;Acc:HGNC:24119]",{"v":0.0611626808171929,"d":"0.06"},{"v":0.106942733881666,"d":"0.11"},{"v":0.571919929453744,"d":"0.57"},{"v":-0.806114915481638,"d":"-0.81"},1,1,"down","no"]
["ENSG00000229255","AC138089.1","ENST00000450847","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000243137","PSG4","ENST00000405312","GO:0005576(extracellular region);GO:0070062(extracellular exosome);GO:0007565(female pregnancy)","NA","NA","NA","pregnancy specific beta-1-glycoprotein 4 [Source:HGNC Symbol;Acc:HGNC:9521]",0,{"v":3.24819891616194E-3,"d":"0.00"},"-inf","-inf",1,1,"down","no"]
["ENSG00000206187","LINC02346","ENST00000383019","NA","NA","NA","NA","long intergenic non-protein coding RNA 2346 [Source:HGNC Symbol;Acc:HGNC:53268]",{"v":0.0053839838641189,"d":"0.01"},{"v":0.0166380636942675,"d":"0.02"},{"v":0.323594377510041,"d":"0.32"},{"v":-1.6277415538959,"d":"-1.63"},1,1,"down","no"]
["MSTRG.1678","AL353801.1","ENST00000425541","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000275393","AC018695.6","ENST00000614011","NA","NA","NA","NA",null,0,{"v":0.042719,"d":"0.04"},"-inf","-inf",1,1,"down","no"]
["ENSG00000156574","NODAL","ENST00000287139;ENST00000414871","GO:0005615(extracellular space);GO:0045766(positive regulation of angiogenesis);GO:0051091(positive regulation of sequence-specific DNA binding transcription factor activity);GO:0070374(positive regulation of ERK1 and ERK2 cascade);GO:0008083(growth factor activity);GO:0005576(extracellular region);GO:0007275(multicellular organism development);GO:0005125(cytokine activity);GO:0060395(SMAD protein signal transduction);GO:0005160(transforming growth factor beta receptor binding);GO:0030509(BMP signaling pathway);GO:0048468(cell development);GO:0022409(positive regulation of cell-cell adhesion);GO:0070698(type I activin receptor binding);GO:0060766(negative regulation of androgen receptor signaling pathway);GO:0016015(morphogen activity);GO:0010862(positive regulation of pathway-restricted SMAD protein phosphorylation);GO:0010575(positive regulation of vascular endothelial growth factor production);GO:1901164(negative regulation of trophoblast cell migration);GO:0050679(positive regulation of epithelial cell proliferation);GO:0060391(positive regulation of SMAD protein import into nucleus);GO:0035987(endodermal cell differentiation);GO:0043280(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process);GO:0032927(positive regulation of activin receptor signaling pathway);GO:0001890(placenta development);GO:1900224(positive regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry);GO:1901383(negative regulation of chorionic trophoblast cell proliferation);GO:0048018(receptor agonist activity);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0001701(in utero embryonic development);GO:0001702(gastrulation with mouth forming second);GO:0001707(mesoderm formation);GO:0001829(trophectodermal cell differentiation);GO:0001831(trophectodermal cellular morphogenesis);GO:0001842(neural fold formation);GO:0001889(liver development);GO:0001892(embryonic placenta development);GO:0001893(maternal placenta development);GO:0001944(vasculature development);GO:0001947(heart looping);GO:0002085(inhibition of neuroepithelial cell differentiation);GO:0007368(determination of left/right symmetry);GO:0007369(gastrulation);GO:0007399(nervous system development);GO:0007420(brain development);GO:0007492(endoderm development);GO:0007507(heart development);GO:0008284(positive regulation of cell proliferation);GO:0009880(embryonic pattern specification);GO:0009948(anterior/posterior axis specification);GO:0009952(anterior/posterior pattern specification);GO:0009966(regulation of signal transduction);GO:0010085(polarity specification of proximal/distal axis);GO:0010470(regulation of gastrulation);GO:0010721(negative regulation of cell development);GO:0016477(cell migration);GO:0019827(stem cell population maintenance);GO:0030324(lung development);GO:0033505(floor plate morphogenesis);GO:0035050(embryonic heart tube development);GO:0038092(nodal signaling pathway);GO:0042074(cell migration involved in gastrulation);GO:0045165(cell fate commitment);GO:0045596(negative regulation of cell differentiation);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0048327(axial mesodermal cell fate specification);GO:0048382(mesendoderm development);GO:0048546(digestive tract morphogenesis);GO:0048646(anatomical structure formation involved in morphogenesis);GO:0048701(embryonic cranial skeleton morphogenesis);GO:0048729(tissue morphogenesis);GO:0048859(formation of anatomical boundary);GO:0055123(digestive system development);GO:0060136(embryonic process involved in female pregnancy);GO:0060137(maternal process involved in parturition);GO:0060460(left lung morphogenesis);GO:0060802(epiblast cell-extraembryonic ectoderm cell signaling involved in anterior/posterior axis specification);GO:0090009(primitive streak formation);GO:0090010(transforming growth factor beta receptor signaling pathway involved in primitive streak formation);GO:1900164(nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry);GO:2000036(regulation of stem cell population maintenance);GO:2000036(regulation of stem cell population maintenance)","04350(TGF-beta signaling pathway);04550(Signaling pathways regulating pluripotency of stem cells);04550(Signaling pathways regulating pluripotency of stem cells)","K04666","NA","nodal growth differentiation factor [Source:HGNC Symbol;Acc:HGNC:7865]",{"v":0.0901735676314235,"d":"0.09"},{"v":0.00940963910218547,"d":"0.01"},{"v":9.58310586114614,"d":"9.58"},{"v":3.26049330567804,"d":"3.26"},1,1,"up","no"]
["ENSG00000230825","AC005532.1","ENST00000447039;ENST00000430266;ENST00000436578","NA","NA","NA","NA",null,{"v":0.0415538496362167,"d":"0.04"},{"v":0.0868338738884398,"d":"0.09"},{"v":0.478544233666267,"d":"0.48"},{"v":-1.0632758102147,"d":"-1.06"},1,1,"down","no"]
["MSTRG.11070","AC097634.3","ENST00000613067","NA","NA","NA","NA",null,{"v":0.062685,"d":"0.06"},{"v":0.10002,"d":"0.10"},{"v":0.626724655068986,"d":"0.63"},{"v":-0.674096345664008,"d":"-0.67"},1,1,"down","no"]
["ENSG00000230667","SETSIP","ENST00000485873;ENST00000596516","GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0006334(nucleosome assembly);GO:0005811(lipid particle);GO:0005737(cytoplasm);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0030154(cell differentiation);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0003682(chromatin binding);GO:0045446(endothelial cell differentiation);GO:0045446(endothelial cell differentiation)","NA","NA","NA","SET-like protein [Source:HGNC Symbol;Acc:HGNC:42937]",{"v":0.055888,"d":"0.06"},{"v":0.010457,"d":"0.01"},{"v":5.34455388734819,"d":"5.34"},{"v":2.41806953047697,"d":"2.42"},1,1,"up","no"]
["ENSG00000224217","BX119904.1","ENST00000432026","NA","NA","NA","NA",null,0,{"v":0.206269,"d":"0.21"},"-inf","-inf",1,1,"down","no"]
["ENSG00000278948","AL031587.5","ENST00000624344","NA","NA","NA","NA",null,{"v":0.901922,"d":"0.90"},0,"inf","inf",1,1,"up","no"]
["ENSG00000138813","C4orf17","ENST00000477187;ENST00000514652","NA","NA","NA","NA","chromosome 4 open reading frame 17 [Source:HGNC Symbol;Acc:HGNC:25274]",{"v":0.0258954875804968,"d":"0.03"},0,"inf","inf",1,1,"up","no"]
["ENSG00000198704","GPX6","ENST00000612264","GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0005576(extracellular region);GO:0098869(cellular oxidant detoxification);GO:0004601(peroxidase activity);GO:0004602(glutathione peroxidase activity);GO:0006979(response to oxidative stress)","00590(Arachidonic acid metabolism);00480(Glutathione metabolism);04918(Thyroid hormone synthesis)","NA","NA","glutathione peroxidase 6 [Source:HGNC Symbol;Acc:HGNC:4558]",0,{"v":0.0177164003964321,"d":"0.02"},"-inf","-inf",1,1,"down","no"]
["ENSG00000228604","AL121759.1","ENST00000434043;ENST00000425746","NA","NA","NA","NA",null,{"v":0.0402076621621622,"d":"0.04"},0,"inf","inf",1,1,"up","no"]
["ENSG00000280241","AC079298.3","ENST00000624941","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["MSTRG.8376","AC008750.1","ENST00000532473","NA","NA","NA","NA",null,{"v":0.466156,"d":"0.47"},{"v":0.33172,"d":"0.33"},{"v":1.4052695044013,"d":"1.41"},{"v":0.49084683889985,"d":"0.49"},1,1,"up","no"]
["MSTRG.2164","OR51M1","ENST00000328611","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0004930(G-protein coupled receptor activity);GO:0007186(G-protein coupled receptor signaling pathway);GO:0005886(plasma membrane);GO:0004871(signal transducer activity);GO:0007165(signal transduction);GO:0004984(olfactory receptor activity);GO:0007608(sensory perception of smell);GO:0050896(response to stimulus);GO:0050911(detection of chemical stimulus involved in sensory perception of smell)","04740(Olfactory transduction)","K04257","NA","olfactory receptor family 51 subfamily M member 1 [Source:HGNC Symbol;Acc:HGNC:14847]",{"v":0.0123728441083191,"d":"0.01"},0,"inf","inf",1,1,"up","no"]
["MSTRG.9784","NEURL2","ENST00000372518;ENST00000545238","GO:0005737(cytoplasm);GO:0016567(protein ubiquitination);GO:0035556(intracellular signal transduction);GO:0005829(cytosol);GO:0043687(post-translational protein modification);GO:0043687(post-translational protein modification)","NA","NA","NA","neuralized E3 ubiquitin protein ligase 2 [Source:HGNC Symbol;Acc:HGNC:16156]",{"v":0.38745796925442,"d":"0.39"},{"v":0.172394439661799,"d":"0.17"},{"v":2.24750850441888,"d":"2.25"},{"v":1.16832657480968,"d":"1.17"},1,1,"up","no"]
["ENSG00000226578","AL132657.1","ENST00000432530","NA","NA","NA","NA",null,{"v":0.153992,"d":"0.15"},0,"inf","inf",1,1,"up","no"]
["ENSG00000227717","AC138749.1","ENST00000567652","NA","NA","NA","NA",null,{"v":3.483E-3,"d":"0.00"},{"v":0.011865,"d":"0.01"},{"v":0.293552465233881,"d":"0.29"},{"v":-1.76830972249459,"d":"-1.77"},1,1,"down","no"]
["ENSG00000121898","CPXM2","ENST00000241305","GO:0005615(extracellular space);GO:0008270(zinc ion binding);GO:0006508(proteolysis);GO:0005576(extracellular region);GO:0031012(extracellular matrix);GO:0004181(metallocarboxypeptidase activity)","NA","NA","NA","carboxypeptidase X, M14 family member 2 [Source:HGNC Symbol;Acc:HGNC:26977]",{"v":0.0171709619263223,"d":"0.02"},{"v":0.00659819592508747,"d":"0.01"},{"v":2.60237224254517,"d":"2.60"},{"v":1.37982733948216,"d":"1.38"},1,1,"up","no"]
["ENSG00000134873","CLDN10","ENST00000376855;ENST00000376873;ENST00000299339","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005198(structural molecule activity);GO:0006811(ion transport);GO:0005886(plasma membrane);GO:0030054(cell junction);GO:0005923(bicellular tight junction);GO:0042802(identical protein binding);GO:0007155(cell adhesion);GO:0016338(calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules);GO:0005737(cytoplasm);GO:0005737(cytoplasm)","04514(Cell adhesion molecules (CAMs));04530(Tight junction);04670(Leukocyte transendothelial migration);05160(Hepatitis C);05160(Hepatitis C)","K06087","NA","claudin 10 [Source:HGNC Symbol;Acc:HGNC:2033]",{"v":0.0237479514792899,"d":"0.02"},{"v":0.0725611576923077,"d":"0.07"},{"v":0.327281871383475,"d":"0.33"},{"v":-1.61139440325782,"d":"-1.61"},1,1,"down","no"]
["MSTRG.7927","AC008894.3","ENST00000624324","NA","NA","NA","NA",null,0,{"v":0.058177,"d":"0.06"},"-inf","-inf",1,1,"down","no"]
["ENSG00000126233","SLURP1","ENST00000246515","GO:0007155(cell adhesion);GO:0005576(extracellular region);GO:0005125(cytokine activity);GO:0005615(extracellular space);GO:2000273(positive regulation of receptor activity);GO:0070062(extracellular exosome);GO:0008285(negative regulation of cell proliferation);GO:0030336(negative regulation of cell migration);GO:0001775(cell activation);GO:0030549(acetylcholine receptor activator activity);GO:0007626(locomotory behavior);GO:0010839(negative regulation of keratinocyte proliferation);GO:0038195(urokinase plasminogen activator signaling pathway);GO:0050884(neuromuscular process controlling posture)","NA","NA","NA","secreted LY6/PLAUR domain containing 1 [Source:HGNC Symbol;Acc:HGNC:18746]",0,{"v":0.033648,"d":"0.03"},"-inf","-inf",1,1,"down","no"]
["ENSG00000250722","SELENOP","ENST00000512980;ENST00000510965","GO:0005576(extracellular region);GO:0070062(extracellular exosome);GO:0006979(response to oxidative stress);GO:0002576(platelet degranulation);GO:0031089(platelet dense granule lumen);GO:0008430(selenium binding);GO:0001887(selenium compound metabolic process);GO:0007420(brain development);GO:0007626(locomotory behavior);GO:0009791(post-embryonic development);GO:0019953(sexual reproduction);GO:0040007(growth);GO:0005615(extracellular space);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016021(integral component of membrane)","NA","NA","NA","selenoprotein P [Source:HGNC Symbol;Acc:HGNC:10751]",{"v":0.0679912842827004,"d":"0.07"},{"v":0.0476447652953586,"d":"0.05"},{"v":1.4270462633452,"d":"1.43"},{"v":0.513032106233996,"d":"0.51"},1,1,"up","no"]
["ENSG00000013297","CLDN11","ENST00000480067;ENST00000064724","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005198(structural molecule activity);GO:0005886(plasma membrane);GO:0030054(cell junction);GO:0005923(bicellular tight junction);GO:0005515(protein binding);GO:0070062(extracellular exosome);GO:0042802(identical protein binding);GO:0016338(calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules);GO:0007155(cell adhesion);GO:0007283(spermatogenesis);GO:0008366(axon ensheathment);GO:0043209(myelin sheath);GO:0045178(basal part of cell);GO:0045178(basal part of cell)","04514(Cell adhesion molecules (CAMs));04530(Tight junction);04670(Leukocyte transendothelial migration);05160(Hepatitis C);05160(Hepatitis C)","K06087","NA","claudin 11 [Source:HGNC Symbol;Acc:HGNC:8514]",{"v":0.0170147118700265,"d":"0.02"},{"v":0.00864784665119363,"d":"0.01"},{"v":1.96750850891627,"d":"1.97"},{"v":0.97636987499312,"d":"0.98"},1,1,"up","no"]
["ENSG00000260412","AL353746.1","ENST00000566293","NA","NA","NA","NA",null,{"v":0.137824,"d":"0.14"},{"v":0.026522,"d":"0.03"},{"v":5.19659150893598,"d":"5.20"},{"v":2.3775656568133,"d":"2.38"},1,1,"up","no"]
["ENSG00000148604","RGR","ENST00000469446;ENST00000483771","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0004930(G-protein coupled receptor activity);GO:0007186(G-protein coupled receptor signaling pathway);GO:0007601(visual perception);GO:0005515(protein binding);GO:0004871(signal transducer activity);GO:0007165(signal transduction);GO:0050896(response to stimulus);GO:0009881(photoreceptor activity);GO:0007602(phototransduction);GO:0018298(protein-chromophore linkage);GO:0005887(integral component of plasma membrane);GO:0008020(G-protein coupled photoreceptor activity);GO:0009584(detection of visible light);GO:0009584(detection of visible light)","NA","NA","NA","retinal G protein coupled receptor [Source:HGNC Symbol;Acc:HGNC:9990]",{"v":0.0168123056860902,"d":"0.02"},0,"inf","inf",1,1,"up","no"]
["ENSG00000120051","CFAP58","ENST00000369704;ENST00000369703","GO:0042995(cell projection);GO:0005515(protein binding);GO:0005615(extracellular space);GO:0005929(cilium);GO:0005929(cilium)","NA","NA","NA","cilia and flagella associated protein 58 [Source:HGNC Symbol;Acc:HGNC:26676]",{"v":0.125724054678692,"d":"0.13"},{"v":0.196206058624577,"d":"0.20"},{"v":0.64077559867432,"d":"0.64"},{"v":-0.642108885252218,"d":"-0.64"},1,1,"down","no"]
["ENSG00000165644","COMTD1","ENST00000491270;ENST00000372538;ENST00000490521;ENST00000470947;ENST00000460899","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0008168(methyltransferase activity);GO:0016740(transferase activity);GO:0032259(methylation);GO:0005515(protein binding);GO:0008171(O-methyltransferase activity);GO:0005739(mitochondrion);GO:0005739(mitochondrion)","NA","NA","NA","catechol-O-methyltransferase domain containing 1 [Source:HGNC Symbol;Acc:HGNC:26309]",{"v":0.65962597721519,"d":"0.66"},{"v":0.391627315822785,"d":"0.39"},{"v":1.68432065528768,"d":"1.68"},{"v":0.752166819969467,"d":"0.75"},1,1,"up","no"]
["MSTRG.4815","IGHV3-33-2","ENST00000517703","NA","NA","NA","NA","immunoglobulin heavy variable 3-33-2 (pseudogene) [Source:HGNC Symbol;Acc:HGNC:5597]",0,0,1,0,1,1,"no","no"]
["MSTRG.13034","AL160163.1","ENST00000417465","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["MSTRG.8557","AC011742.3","ENST00000439053","NA","NA","NA","NA",null,{"v":0.062685,"d":"0.06"},0,"inf","inf",1,1,"up","no"]
["ENSG00000121410","A1BG","ENST00000598345;ENST00000263100;ENST00000596924;ENST00000595014","GO:0005576(extracellular region);GO:0005615(extracellular space);GO:0003674(molecular_function);GO:0008150(biological_process);GO:0070062(extracellular exosome);GO:0072562(blood microparticle);GO:0043312(neutrophil degranulation);GO:0002576(platelet degranulation);GO:0034774(secretory granule lumen);GO:1904813(ficolin-1-rich granule lumen);GO:0031093(platelet alpha granule lumen);GO:0031093(platelet alpha granule lumen)","NA","NA","NA","alpha-1-B glycoprotein [Source:HGNC Symbol;Acc:HGNC:5]",{"v":0.1348744443335,"d":"0.13"},{"v":0.144809803045432,"d":"0.14"},{"v":0.931390289172516,"d":"0.93"},{"v":-0.102542254425158,"d":"-0.10"},1,1,"down","no"]
["ENSG00000283189","AC104452.1","ENST00000636461;ENST00000638014;ENST00000636204;ENST00000637088;ENST00000638115","GO:0005654(nucleoplasm);GO:0016740(transferase activity);GO:0005739(mitochondrion);GO:0008483(transaminase activity);GO:0004047(aminomethyltransferase activity);GO:0006546(glycine catabolic process);GO:0032259(methylation);GO:0032259(methylation)","NA","NA","NA",null,{"v":0.00809355016894373,"d":"0.01"},{"v":0.767820910092552,"d":"0.77"},{"v":0.0105409348228979,"d":"0.01"},{"v":-6.5678533717034,"d":"-6.57"},1,1,"down","no"]
["ENSG00000130997","POLN","ENST00000514858;ENST00000511885;ENST00000382865;ENST00000515357","GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0016740(transferase activity);GO:0003677(DNA binding);GO:0006281(DNA repair);GO:0006974(cellular response to DNA damage stimulus);GO:0006260(DNA replication);GO:0016779(nucleotidyltransferase activity);GO:0003887(DNA-directed DNA polymerase activity);GO:0005737(cytoplasm);GO:0006261(DNA-dependent DNA replication);GO:0005515(protein binding);GO:0036297(interstrand cross-link repair);GO:0000724(double-strand break repair via homologous recombination);GO:0030332(cyclin binding);GO:0019985(translesion synthesis);GO:0071897(DNA biosynthetic process);GO:0071897(DNA biosynthetic process)","03460(Fanconi anemia pathway);03460(Fanconi anemia pathway)","K16618","EC:2.7.7.7","DNA polymerase nu [Source:HGNC Symbol;Acc:HGNC:18870]",{"v":0.0398914724776583,"d":"0.04"},{"v":0.0685944407460174,"d":"0.07"},{"v":0.581555473647832,"d":"0.58"},{"v":-0.782011280249118,"d":"-0.78"},1,1,"down","no"]
["ENSG00000134817","APLNR","ENST00000606794","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0004930(G-protein coupled receptor activity);GO:0007186(G-protein coupled receptor signaling pathway);GO:0005886(plasma membrane);GO:0004871(signal transducer activity);GO:0007165(signal transduction);GO:0007275(multicellular organism development);GO:0007507(heart development);GO:0005887(integral component of plasma membrane);GO:0004872(receptor activity);GO:0045766(positive regulation of angiogenesis);GO:0051281(positive regulation of release of sequestered calcium ion into cytosol);GO:0043951(negative regulation of cAMP-mediated signaling);GO:0007369(gastrulation);GO:1904325(positive regulation of inhibitory G-protein coupled receptor phosphorylation);GO:0050878(regulation of body fluid levels)","04371(Apelin signaling pathway);04080(Neuroactive ligand-receptor interaction)","K04174","NA","apelin receptor [Source:HGNC Symbol;Acc:HGNC:339]",0,{"v":0.0122057191011236,"d":"0.01"},"-inf","-inf",1,1,"down","no"]
["MSTRG.5302","TMEM266","ENST00000388942;ENST00000561302","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0005886(plasma membrane)","NA","NA","NA","transmembrane protein 266 [Source:HGNC Symbol;Acc:HGNC:26763]",0,{"v":0.0120584512820513,"d":"0.01"},"-inf","-inf",1,1,"down","no"]
["ENSG00000204963","PCDHA7","ENST00000356878","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0046872(metal ion binding);GO:0005509(calcium ion binding);GO:0007155(cell adhesion);GO:0007156(homophilic cell adhesion via plasma membrane adhesion molecules);GO:0005886(plasma membrane);GO:0005887(integral component of plasma membrane);GO:0007267(cell-cell signaling);GO:0042802(identical protein binding);GO:0007399(nervous system development);GO:0009988(cell-cell recognition)","NA","NA","NA","protocadherin alpha 7 [Source:HGNC Symbol;Acc:HGNC:8673]",{"v":0.017761701105736,"d":"0.02"},{"v":0.040595000691085,"d":"0.04"},{"v":0.43753419887579,"d":"0.44"},{"v":-1.19253230852471,"d":"-1.19"},1,1,"down","no"]
["ENSG00000233293","AL133343.3","ENST00000413983","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000232553","CLK2P1","ENST00000416636","NA","NA","NA","NA","CDC like kinase 2, pseudogene 1 [Source:HGNC Symbol;Acc:HGNC:2070]",{"v":0.034692,"d":"0.03"},0,"inf","inf",1,1,"up","no"]
["ENSG00000226881","H3F3AP5","ENST00000475267","NA","NA","NA","NA","H3 histone, family 3A, pseudogene 5 [Source:HGNC Symbol;Acc:HGNC:42981]",0,{"v":0.053175,"d":"0.05"},"-inf","-inf",1,1,"down","no"]
["MSTRG.3488","AC025165.2","ENST00000549477","NA","NA","NA","NA",null,{"v":0.772034,"d":"0.77"},{"v":0.10285,"d":"0.10"},{"v":7.50640738940204,"d":"7.51"},{"v":2.90812259061402,"d":"2.91"},1,1,"up","no"]
["ENSG00000226179","LINC00685","ENST00000391707","NA","NA","NA","NA","long intergenic non-protein coding RNA 685 [Source:HGNC Symbol;Acc:HGNC:27560]",{"v":2.094388,"d":"2.09"},{"v":0.49227,"d":"0.49"},{"v":4.25455136408881,"d":"4.25"},{"v":2.08900700995389,"d":"2.09"},1,1,"up","no"]
["ENSG00000232352","SEMA3B-AS1","ENST00000421735","NA","NA","NA","NA","SEMA3B antisense RNA 1 (head to head) [Source:HGNC Symbol;Acc:HGNC:49096]",0,0,1,0,1,1,"no","no"]
["MSTRG.76","MMP23A","ENST00000234610","NA","NA","NA","NA","matrix metallopeptidase 23A (pseudogene) [Source:HGNC Symbol;Acc:HGNC:7170]",{"v":0.725312,"d":"0.73"},{"v":0.264618,"d":"0.26"},{"v":2.74097756010551,"d":"2.74"},{"v":1.45469051712501,"d":"1.45"},1,1,"up","no"]
["ENSG00000050030","NEXMIF","ENST00000055682","GO:0007275(multicellular organism development);GO:0007399(nervous system development);GO:0005634(nucleus);GO:0042276(error-prone translesion synthesis);GO:0016035(zeta DNA polymerase complex)","NA","NA","NA","neurite extension and migration factor [Source:HGNC Symbol;Acc:HGNC:29433]",{"v":0.00763623875138216,"d":"0.01"},{"v":0.0136666844433104,"d":"0.01"},{"v":0.558748450149514,"d":"0.56"},{"v":-0.83972917031796,"d":"-0.84"},1,1,"down","no"]
["ENSG00000227484","CR559946.1","ENST00000453835","NA","NA","NA","NA",null,0,{"v":0.116852,"d":"0.12"},"-inf","-inf",1,1,"down","no"]
["ENSG00000182634","OR10G7","ENST00000330487","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0004930(G-protein coupled receptor activity);GO:0007186(G-protein coupled receptor signaling pathway);GO:0005886(plasma membrane);GO:0004871(signal transducer activity);GO:0007165(signal transduction);GO:0004984(olfactory receptor activity);GO:0007608(sensory perception of smell);GO:0050896(response to stimulus);GO:0050911(detection of chemical stimulus involved in sensory perception of smell)","04740(Olfactory transduction)","K04257","NA","olfactory receptor family 10 subfamily G member 7 [Source:HGNC Symbol;Acc:HGNC:14842]",{"v":0.0149035407364453,"d":"0.01"},{"v":9.83302058567701E-3,"d":"0.01"},{"v":1.51566251759445,"d":"1.52"},{"v":0.59994855404036,"d":"0.60"},1,1,"up","no"]
["ENSG00000270505","IGHV1OR15-1","ENST00000604066","GO:0003823(antigen binding);GO:0034987(immunoglobulin receptor binding);GO:0006910(phagocytosis, recognition);GO:0006911(phagocytosis, engulfment);GO:0006958(complement activation, classical pathway);GO:0042742(defense response to bacterium);GO:0045087(innate immune response);GO:0050853(B cell receptor signaling pathway);GO:0050871(positive regulation of B cell activation);GO:0009897(external side of plasma membrane);GO:0042571(immunoglobulin complex, circulating);GO:0072562(blood microparticle)","NA","NA","NA","immunoglobulin heavy variable 1/OR15-1 (non-functional) [Source:HGNC Symbol;Acc:HGNC:5563]",0,{"v":0.107171,"d":"0.11"},"-inf","-inf",1,1,"down","no"]
["MSTRG.387","AL355864.1","ENST00000401937","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000283005","CDC27P3","ENST00000635418","NA","NA","NA","NA","cell division cycle 27 pseudogene 3 [Source:HGNC Symbol;Acc:HGNC:51754]",0,{"v":0.012023,"d":"0.01"},"-inf","-inf",1,1,"down","no"]
["MSTRG.11229","PRR23B","ENST00000329447","NA","NA","NA","NA","proline rich 23B [Source:HGNC Symbol;Acc:HGNC:33764]",{"v":0.023677,"d":"0.02"},0,"inf","inf",1,1,"up","no"]
["MSTRG.6770","MIR6779","ENST00000617283","NA","NA","NA","NA","microRNA 6779 [Source:HGNC Symbol;Acc:HGNC:50148]",{"v":0.002677,"d":"0.00"},{"v":0.002376,"d":"0.00"},{"v":1.1266835016835,"d":"1.13"},{"v":0.172082302840012,"d":"0.17"},1,1,"up","no"]
["ENSG00000138083","SIX3","ENST00000260653","GO:0005634(nucleus);GO:0006355(regulation of transcription, DNA-templated);GO:0006366(transcription from RNA polymerase II promoter);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0000981(RNA polymerase II transcription factor activity, sequence-specific DNA binding);GO:0005515(protein binding);GO:0007275(multicellular organism development);GO:0003713(transcription coactivator activity);GO:0007420(brain development);GO:0001654(eye development);GO:0007601(visual perception);GO:0042127(regulation of cell proliferation);GO:0045892(negative regulation of transcription, DNA-templated);GO:0045665(negative regulation of neuron differentiation);GO:1902742(apoptotic process involved in development);GO:0002088(lens development in camera-type eye);GO:0000980(RNA polymerase II distal enhancer sequence-specific DNA binding);GO:0001205(transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding);GO:0001222(transcription corepressor binding);GO:0003705(transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding);GO:0005102(receptor binding);GO:0042826(histone deacetylase binding);GO:0043565(sequence-specific DNA binding);GO:0000060(protein import into nucleus, translocation);GO:0002070(epithelial cell maturation);GO:0003404(optic vesicle morphogenesis);GO:0006606(protein import into nucleus);GO:0009946(proximal/distal axis specification);GO:0014016(neuroblast differentiation);GO:0021536(diencephalon development);GO:0021537(telencephalon development);GO:0021797(forebrain anterior/posterior pattern specification);GO:0021798(forebrain dorsal/ventral pattern formation);GO:0021846(cell proliferation in forebrain);GO:0021978(telencephalon regionalization);GO:0021983(pituitary gland development);GO:0030178(negative regulation of Wnt signaling pathway);GO:0043010(camera-type eye development);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0048512(circadian behavior);GO:0060235(lens induction in camera-type eye);GO:0061074(regulation of neural retina development);GO:0070306(lens fiber cell differentiation);GO:0097402(neuroblast migration);GO:1901987(regulation of cell cycle phase transition);GO:1902692(regulation of neuroblast proliferation);GO:1990086(lens fiber cell apoptotic process);GO:2000177(regulation of neural precursor cell proliferation)","NA","NA","NA","SIX homeobox 3 [Source:HGNC Symbol;Acc:HGNC:10889]",{"v":0.003463,"d":"0.00"},{"v":0.017842,"d":"0.02"},{"v":0.194092590516758,"d":"0.19"},{"v":-2.36518305065734,"d":"-2.37"},1,1,"down","no"]
["ENSG00000279117","AP001972.5","ENST00000624624","NA","NA","NA","NA",null,{"v":12.568232,"d":"12.57"},0,"inf","inf",1,1,"up","no"]
["MSTRG.11801","RTEL1P1","ENST00000504490","NA","NA","NA","NA","regulator of telomere elongation helicase 1 pseudogene 1 [Source:HGNC Symbol;Acc:HGNC:44213]",{"v":0.01088,"d":"0.01"},{"v":0.012381,"d":"0.01"},{"v":0.878765850900574,"d":"0.88"},{"v":-0.186449287590489,"d":"-0.19"},1,1,"down","no"]
["ENSG00000280409","LINC01101","ENST00000622953","NA","NA","NA","NA","long intergenic non-protein coding RNA 1101 [Source:HGNC Symbol;Acc:HGNC:25923]",0,{"v":0.024217,"d":"0.02"},"-inf","-inf",1,1,"down","no"]
["MSTRG.6381","AC040977.1","ENST00000573222","NA","NA","NA","NA",null,{"v":0.902523,"d":"0.90"},{"v":1.176854,"d":"1.18"},{"v":0.766894619043654,"d":"0.77"},{"v":-0.382899747965203,"d":"-0.38"},1,1,"down","no"]
["ENSG00000153896","ZNF599","ENST00000587354;ENST00000588788;ENST00000588760;ENST00000329285","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0005622(intracellular);GO:0005515(protein binding);GO:0005515(protein binding)","NA","NA","NA","zinc finger protein 599 [Source:HGNC Symbol;Acc:HGNC:26408]",{"v":0.21421686815774,"d":"0.21"},{"v":0.0587416244849912,"d":"0.06"},{"v":3.64676445426656,"d":"3.65"},{"v":1.86661701852901,"d":"1.87"},1,1,"up","no"]
["ENSG00000231039","AL355303.1","ENST00000428920","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000185013","NT5C1B","ENST00000490687;ENST00000460052","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0000287(magnesium ion binding);GO:0016787(hydrolase activity);GO:0016311(dephosphorylation);GO:0000166(nucleotide binding);GO:0008253(5'-nucleotidase activity);GO:0009117(nucleotide metabolic process);GO:0005829(cytosol);GO:0006195(purine nucleotide catabolic process);GO:0006195(purine nucleotide catabolic process)","00230(Purine metabolism);00240(Pyrimidine metabolism);00760(Nicotinate and nicotinamide metabolism);00760(Nicotinate and nicotinamide metabolism)","NA","NA","5'-nucleotidase, cytosolic IB [Source:HGNC Symbol;Acc:HGNC:17818]",0,{"v":0.0100386215199398,"d":"0.01"},"-inf","-inf",1,1,"down","no"]
["ENSG00000254933","AP000785.1","ENST00000527314","NA","NA","NA","NA",null,{"v":0.167707,"d":"0.17"},0,"inf","inf",1,1,"up","no"]
["ENSG00000130762","ARHGEF16","ENST00000378378;ENST00000378373","GO:0005737(cytoplasm);GO:0005089(Rho guanyl-nucleotide exchange factor activity);GO:0035023(regulation of Rho protein signal transduction);GO:0005515(protein binding);GO:0005085(guanyl-nucleotide exchange factor activity);GO:0005829(cytosol);GO:0045296(cadherin binding);GO:0051056(regulation of small GTPase mediated signal transduction);GO:0090630(activation of GTPase activity);GO:0030971(receptor tyrosine kinase binding);GO:0060326(cell chemotaxis);GO:0043065(positive regulation of apoptotic process);GO:0017048(Rho GTPase binding);GO:0030165(PDZ domain binding);GO:0090004(positive regulation of establishment of protein localization to plasma membrane);GO:0043547(positive regulation of GTPase activity);GO:0043547(positive regulation of GTPase activity)","NA","NA","NA","Rho guanine nucleotide exchange factor 16 [Source:HGNC Symbol;Acc:HGNC:15515]",{"v":0.0267378777637965,"d":"0.03"},{"v":0.0207074080532087,"d":"0.02"},{"v":1.2912228172204,"d":"1.29"},{"v":0.368737977842228,"d":"0.37"},1,1,"up","no"]
["ENSG00000100033","PRODH","ENST00000609229;ENST00000482858;ENST00000429300","GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0004657(proline dehydrogenase activity);GO:0006560(proline metabolic process);GO:0006562(proline catabolic process);GO:0005739(mitochondrion);GO:0005759(mitochondrial matrix);GO:0071949(FAD binding);GO:0005743(mitochondrial inner membrane);GO:0008631(intrinsic apoptotic signaling pathway in response to oxidative stress);GO:0010133(proline catabolic process to glutamate);GO:0010942(positive regulation of cell death);GO:0019470(4-hydroxyproline catabolic process);GO:0019470(4-hydroxyproline catabolic process)","00330(Arginine and proline metabolism);00330(Arginine and proline metabolism)","NA","NA","proline dehydrogenase 1 [Source:HGNC Symbol;Acc:HGNC:9453]",{"v":0.00565588833181404,"d":"0.01"},{"v":0.0163488317000912,"d":"0.02"},{"v":0.345950611980579,"d":"0.35"},{"v":-1.53136200192832,"d":"-1.53"},1,1,"down","no"]
["ENSG00000259580","AC023908.2","ENST00000558616","NA","NA","NA","NA",null,0,{"v":0.000336,"d":"0.00"},"-inf","-inf",1,1,"down","no"]
["ENSG00000268738","HSFX2","ENST00000598963","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0043565(sequence-specific DNA binding);GO:0005515(protein binding)","NA","NA","NA","heat shock transcription factor family, X-linked 2 [Source:HGNC Symbol;Acc:HGNC:32701]",{"v":0.225485,"d":"0.23"},{"v":0.374638,"d":"0.37"},{"v":0.601874342698819,"d":"0.60"},{"v":-0.732465777483785,"d":"-0.73"},1,1,"down","no"]
["MSTRG.14080","TRBV5-5","ENST00000390372","NA","NA","NA","NA","T-cell receptor beta variable 5-5 [Source:HGNC Symbol;Acc:HGNC:12222]",{"v":1.462444,"d":"1.46"},0,"inf","inf",1,1,"up","no"]
["ENSG00000164556","FAM183BP","ENST00000409072","NA","NA","NA","NA","family with sequence similarity 183 member B, pseudogene [Source:HGNC Symbol;Acc:HGNC:34511]",{"v":0.051728,"d":"0.05"},0,"inf","inf",1,1,"up","no"]
["MSTRG.7014","AC002401.2","ENST00000511361","NA","NA","NA","NA",null,0,{"v":0.106102,"d":"0.11"},"-inf","-inf",1,1,"down","no"]
["ENSG00000111799","COL12A1","ENST00000322507","GO:0005615(extracellular space);GO:0007155(cell adhesion);GO:0005576(extracellular region);GO:0005581(collagen trimer);GO:0005578(proteinaceous extracellular matrix);GO:0070062(extracellular exosome);GO:0031012(extracellular matrix);GO:0030574(collagen catabolic process);GO:0005788(endoplasmic reticulum lumen);GO:0001501(skeletal system development);GO:1903561(extracellular vesicle);GO:0030199(collagen fibril organization);GO:0035987(endodermal cell differentiation);GO:0030020(extracellular matrix structural constituent conferring tensile strength);GO:0005595(collagen type XII trimer)","04974(Protein digestion and absorption)","K08132","NA","collagen type XII alpha 1 chain [Source:HGNC Symbol;Acc:HGNC:2188]",{"v":0.0301007115615736,"d":"0.03"},{"v":0.044283653633523,"d":"0.04"},{"v":0.679725115065645,"d":"0.68"},{"v":-0.556976665155986,"d":"-0.56"},1,1,"down","no"]
["ENSG00000137491","SLCO2B1","ENST00000289575","GO:0006810(transport);GO:0005215(transporter activity);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0006811(ion transport);GO:0005886(plasma membrane);GO:0015125(bile acid transmembrane transporter activity);GO:0015347(sodium-independent organic anion transmembrane transporter activity);GO:0001889(liver development);GO:0015721(bile acid and bile salt transport);GO:0071718(sodium-independent icosanoid transport);GO:0016324(apical plasma membrane);GO:0043252(sodium-independent organic anion transport);GO:0005887(integral component of plasma membrane);GO:0008514(organic anion transmembrane transporter activity)","NA","NA","NA","solute carrier organic anion transporter family member 2B1 [Source:HGNC Symbol;Acc:HGNC:10962]",{"v":0.0157296512414259,"d":"0.02"},{"v":0.012285452420056,"d":"0.01"},{"v":1.28034774004311,"d":"1.28"},{"v":0.356535696710816,"d":"0.36"},1,1,"up","no"]
["MSTRG.6843","WNK4","ENST00000246914","GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0006811(ion transport);GO:0005515(protein binding);GO:0065009(regulation of molecular function);GO:0030054(cell junction);GO:0035556(intracellular signal transduction);GO:0005923(bicellular tight junction);GO:0005829(cytosol);GO:0070294(renal sodium ion absorption);GO:0016020(membrane);GO:0019869(chloride channel inhibitor activity);GO:0010766(negative regulation of sodium ion transport);GO:0006821(chloride transport);GO:0008104(protein localization);GO:0050794(regulation of cellular process);GO:0050801(ion homeostasis);GO:0072156(distal tubule morphogenesis);GO:0090188(negative regulation of pancreatic juice secretion);GO:0005737(cytoplasm)","NA","NA","NA","WNK lysine deficient protein kinase 4 [Source:HGNC Symbol;Acc:HGNC:14544]",{"v":0.0367055781096483,"d":"0.04"},{"v":0.034690533307133,"d":"0.03"},{"v":1.05808630223915,"d":"1.06"},{"v":0.0814573048948399,"d":"0.08"},1,1,"up","no"]
["ENSG00000114248","LRRC31","ENST00000316428","NA","NA","NA","NA","leucine rich repeat containing 31 [Source:HGNC Symbol;Acc:HGNC:26261]",{"v":0.00965015097976229,"d":"0.01"},{"v":0.00925187279151943,"d":"0.01"},{"v":1.04304838568554,"d":"1.04"},{"v":0.0608060841946388,"d":"0.06"},1,1,"up","no"]
["ENSG00000227347","HNRNPKP2","ENST00000447355","NA","NA","NA","NA","heterogeneous nuclear ribonucleoprotein K pseudogene 2 [Source:HGNC Symbol;Acc:HGNC:42375]",0,{"v":0.015536,"d":"0.02"},"-inf","-inf",1,1,"down","no"]
["ENSG00000231265","TRERNA1","ENST00000431460","NA","NA","NA","NA","translation regulatory long non-coding RNA 1 [Source:HGNC Symbol;Acc:HGNC:44307]",0,0,1,0,1,1,"no","no"]
["ENSG00000135248","FAM71F1","ENST00000485070;ENST00000484425;ENST00000315184","GO:0005634(nucleus);GO:0005634(nucleus)","NA","NA","NA","family with sequence similarity 71 member F1 [Source:HGNC Symbol;Acc:HGNC:30704]",{"v":0.0406779603332011,"d":"0.04"},{"v":0.0325601348671162,"d":"0.03"},{"v":1.24931793124369,"d":"1.25"},{"v":0.321140666265815,"d":"0.32"},1,1,"up","no"]
["ENSG00000155087","ODF1","ENST00000285402","GO:0005634(nucleus);GO:0005515(protein binding);GO:0007275(multicellular organism development);GO:0030154(cell differentiation);GO:0007283(spermatogenesis);GO:0019904(protein domain specific binding);GO:0001520(outer dense fiber)","NA","NA","NA","outer dense fiber of sperm tails 1 [Source:HGNC Symbol;Acc:HGNC:8113]",0,{"v":0.0795428598848369,"d":"0.08"},"-inf","-inf",1,1,"down","no"]
["ENSG00000261786","AC006058.1","ENST00000568686","NA","NA","NA","NA",null,{"v":0.056978,"d":"0.06"},{"v":0.008494,"d":"0.01"},{"v":6.70802919708029,"d":"6.71"},{"v":2.74588896832851,"d":"2.75"},1,1,"up","no"]
["ENSG00000251423","AC016576.1","ENST00000637153","NA","NA","NA","NA",null,{"v":0.0141797875862069,"d":"0.01"},0,"inf","inf",1,1,"up","no"]
["ENSG00000130675","MNX1","ENST00000543409;ENST00000252971","GO:0005634(nucleus);GO:0005730(nucleolus);GO:0005829(cytosol);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0043565(sequence-specific DNA binding);GO:0048812(neuron projection morphogenesis);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0009653(anatomical structure morphogenesis);GO:0006959(humoral immune response);GO:0021520(spinal cord motor neuron cell fate specification);GO:0031018(endocrine pancreas development);GO:0031018(endocrine pancreas development)","04950(Maturity onset diabetes of the young);04950(Maturity onset diabetes of the young)","K08025","NA","motor neuron and pancreas homeobox 1 [Source:HGNC Symbol;Acc:HGNC:4979]",{"v":0.00843007044264636,"d":"0.01"},{"v":0.0139337358400762,"d":"0.01"},{"v":0.605011501538575,"d":"0.61"},{"v":-0.724965525963037,"d":"-0.72"},1,1,"down","no"]
["ENSG00000184471","C1QTNF8","ENST00000328449","GO:0005515(protein binding);GO:0005576(extracellular region);GO:0005581(collagen trimer)","NA","NA","NA","C1q and TNF related 8 [Source:HGNC Symbol;Acc:HGNC:31374]",0,{"v":0.0509508378531073,"d":"0.05"},"-inf","-inf",1,1,"down","no"]
["ENSG00000249956","UGT2B24P","ENST00000514441","NA","NA","NA","NA","UDP glucuronosyltransferase family 2 member B24, pseudogene [Source:HGNC Symbol;Acc:HGNC:12548]",{"v":0.013874,"d":"0.01"},0,"inf","inf",1,1,"up","no"]
["ENSG00000148584","A1CF","ENST00000395489","GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0006397(mRNA processing);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005654(nucleoplasm);GO:0003727(single-stranded RNA binding);GO:0016556(mRNA modification);GO:0030895(apolipoprotein B mRNA editing enzyme complex);GO:0005783(endoplasmic reticulum);GO:0005515(protein binding);GO:0050821(protein stabilization);GO:0016554(cytidine to uridine editing);GO:0007566(embryo implantation);GO:0010609(mRNA localization resulting in posttranscriptional regulation of gene expression)","NA","NA","NA","APOBEC1 complementation factor [Source:HGNC Symbol;Acc:HGNC:24086]",{"v":2.03956950952827E-3,"d":"0.00"},0,"inf","inf",1,1,"up","no"]
["ENSG00000214894","LINC00243","ENST00000399196;ENST00000419357","NA","NA","NA","NA","long intergenic non-protein coding RNA 243 [Source:HGNC Symbol;Acc:HGNC:30956]",{"v":0.743762371257485,"d":"0.74"},{"v":0.758226350990327,"d":"0.76"},{"v":0.980923928964022,"d":"0.98"},{"v":-0.0277868356719252,"d":"-0.03"},1,1,"down","no"]
["ENSG00000172969","FRG2C","ENST00000308062","GO:0005634(nucleus)","NA","NA","NA","FSHD region gene 2 family member C [Source:HGNC Symbol;Acc:HGNC:33626]",{"v":0.011049,"d":"0.01"},0,"inf","inf",1,1,"up","no"]
["ENSG00000232855","AF165147.1","ENST00000433310","NA","NA","NA","NA",null,{"v":0.0654727074402939,"d":"0.07"},{"v":0.0188116659522351,"d":"0.02"},{"v":3.4804311115526,"d":"3.48"},{"v":1.7992660198605,"d":"1.80"},1,1,"up","no"]
["ENSG00000166736","HTR3A","ENST00000355556;ENST00000504030","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005216(ion channel activity);GO:0006811(ion transport);GO:0098655(cation transmembrane transport);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0030054(cell junction);GO:0045202(synapse);GO:0045211(postsynaptic membrane);GO:0005230(extracellular ligand-gated ion channel activity);GO:0007165(signal transduction);GO:0034220(ion transmembrane transport);GO:0015276(ligand-gated ion channel activity);GO:0022850(serotonin-gated cation-selective channel activity);GO:1904602(serotonin-activated cation-selective channel complex);GO:0032154(cleavage furrow);GO:0051378(serotonin binding);GO:0060079(excitatory postsynaptic potential);GO:0060078(regulation of postsynaptic membrane potential);GO:0022848(acetylcholine-gated cation-selective channel activity);GO:0032414(positive regulation of ion transmembrane transporter activity);GO:0042220(response to cocaine);GO:0045471(response to ethanol);GO:0071363(cellular response to growth factor stimulus);GO:0005737(cytoplasm);GO:0030424(axon);GO:0043025(neuronal cell body);GO:0043025(neuronal cell body)","04726(Serotonergic synapse);04742(Taste transduction);04742(Taste transduction)","K04819","NA","5-hydroxytryptamine receptor 3A [Source:HGNC Symbol;Acc:HGNC:5297]",{"v":0.0199034458874459,"d":"0.02"},{"v":0.0478484642857143,"d":"0.05"},{"v":0.415968332203889,"d":"0.42"},{"v":-1.26545439515427,"d":"-1.27"},1,1,"down","no"]
["MSTRG.8216","RN7SL368P","ENST00000473384","NA","NA","NA","NA","RNA, 7SL, cytoplasmic 368, pseudogene [Source:HGNC Symbol;Acc:HGNC:46384]",{"v":0.185567,"d":"0.19"},{"v":0.467768,"d":"0.47"},{"v":0.396707342101213,"d":"0.40"},{"v":-1.33385299633286,"d":"-1.33"},1,1,"down","no"]
["ENSG00000271046","AL512631.1","ENST00000604086","NA","NA","NA","NA",null,{"v":0.121774,"d":"0.12"},0,"inf","inf",1,1,"up","no"]
["ENSG00000260909","AC012186.1","ENST00000566702","NA","NA","NA","NA",null,{"v":2.153E-3,"d":"0.00"},0,"inf","inf",1,1,"up","no"]
["ENSG00000253764","AC019257.1","ENST00000517676","NA","NA","NA","NA",null,{"v":0.0457896952736318,"d":"0.05"},0,"inf","inf",1,1,"up","no"]
["ENSG00000237510","GPAT2P1","ENST00000444924;ENST00000471661","NA","NA","NA","NA","glycerol-3-phosphate acyltransferase 2 pseudogene 1 [Source:HGNC Symbol;Acc:HGNC:52330]",{"v":0.0475022222717149,"d":"0.05"},{"v":0.0317672587973274,"d":"0.03"},{"v":1.49532015257518,"d":"1.50"},{"v":0.580454402874075,"d":"0.58"},1,1,"up","no"]
["ENSG00000130413","STK33","ENST00000486305;ENST00000526517;ENST00000447869","GO:0005737(cytoplasm);GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0048471(perinuclear region of cytoplasm);GO:0005622(intracellular);GO:0035556(intracellular signal transduction);GO:0018105(peptidyl-serine phosphorylation);GO:0046777(protein autophosphorylation);GO:0018107(peptidyl-threonine phosphorylation);GO:0018107(peptidyl-threonine phosphorylation)","NA","NA","NA","serine/threonine kinase 33 [Source:HGNC Symbol;Acc:HGNC:14568]",{"v":0.0238779960521121,"d":"0.02"},{"v":0.0265227214107119,"d":"0.03"},{"v":0.900284540276035,"d":"0.90"},{"v":-0.151547049037177,"d":"-0.15"},1,1,"down","no"]
["ENSG00000011201","ANOS1","ENST00000262648;ENST00000488294","GO:0016020(membrane);GO:0007155(cell adhesion);GO:0005576(extracellular region);GO:0010951(negative regulation of endopeptidase activity);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0006935(chemotaxis);GO:0030414(peptidase inhibitor activity);GO:0010466(negative regulation of peptidase activity);GO:0008201(heparin binding);GO:0004867(serine-type endopeptidase inhibitor activity);GO:0005615(extracellular space);GO:0006928(movement of cell or subcellular component);GO:0007411(axon guidance);GO:0005201(extracellular matrix structural constituent);GO:0005578(proteinaceous extracellular matrix);GO:0008543(fibroblast growth factor receptor signaling pathway);GO:0008543(fibroblast growth factor receptor signaling pathway)","NA","NA","NA","anosmin 1 [Source:HGNC Symbol;Acc:HGNC:6211]",{"v":0.0347991625297995,"d":"0.03"},{"v":0.00639811583228159,"d":"0.01"},{"v":5.43897038472184,"d":"5.44"},{"v":2.44333357032773,"d":"2.44"},1,1,"up","no"]
["ENSG00000226490","AC138647.1","ENST00000427937","NA","NA","NA","NA",null,0,{"v":0.063132,"d":"0.06"},"-inf","-inf",1,1,"down","no"]
["MSTRG.9044","AC108463.1","ENST00000450258","NA","NA","NA","NA",null,{"v":0.450872,"d":"0.45"},{"v":0.256826,"d":"0.26"},{"v":1.75555434418634,"d":"1.76"},{"v":0.811926656358016,"d":"0.81"},1,1,"up","no"]
["ENSG00000235649","MXRA5Y","ENST00000420610","NA","NA","NA","NA","matrix remodeling associated 5, Y-linked (pseudogene) [Source:HGNC Symbol;Acc:HGNC:23932]",0,{"v":0.005703,"d":"0.01"},"-inf","-inf",1,1,"down","no"]
["ENSG00000204989","OR4D8P","ENST00000431137","NA","NA","NA","NA","olfactory receptor family 4 subfamily D member 8 pseudogene [Source:HGNC Symbol;Acc:HGNC:15177]",{"v":0.055271,"d":"0.06"},0,"inf","inf",1,1,"up","no"]
["ENSG00000136698","CFC1","ENST00000615342","GO:0016020(membrane);GO:0005886(plasma membrane);GO:0005576(extracellular region);GO:0007275(multicellular organism development);GO:0031225(anchored component of membrane);GO:0003674(molecular_function);GO:0005575(cellular_component);GO:0007368(determination of left/right symmetry);GO:0007369(gastrulation);GO:0038100(nodal binding);GO:0038092(nodal signaling pathway)","NA","NA","NA","cripto, FRL-1, cryptic family 1 [Source:HGNC Symbol;Acc:HGNC:18292]",{"v":0.0179049850209706,"d":"0.02"},{"v":0.0119897291791492,"d":"0.01"},{"v":1.49336025471771,"d":"1.49"},{"v":0.578562239819075,"d":"0.58"},1,1,"up","no"]
["ENSG00000004776","HSPB6","ENST00000004982","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0042803(protein homodimerization activity);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0005212(structural constituent of eye lens);GO:0051082(unfolded protein binding);GO:0051087(chaperone binding);GO:0006937(regulation of muscle contraction);GO:0010667(negative regulation of cardiac muscle cell apoptotic process);GO:0045766(positive regulation of angiogenesis);GO:0061077(chaperone-mediated protein folding)","NA","NA","NA","heat shock protein family B (small) member 6 [Source:HGNC Symbol;Acc:HGNC:26511]",0,{"v":0.0662752980825102,"d":"0.07"},"-inf","-inf",1,1,"down","no"]
["MSTRG.5797","AC009086.3","ENST00000623486","NA","NA","NA","NA",null,0,{"v":0.168977,"d":"0.17"},"-inf","-inf",1,1,"down","no"]
["MSTRG.15005","AL441992.1","ENST00000443631","NA","NA","NA","NA",null,{"v":1.262058,"d":"1.26"},{"v":0.638728,"d":"0.64"},{"v":1.97589271176463,"d":"1.98"},{"v":0.982504612708361,"d":"0.98"},1,1,"up","no"]
["ENSG00000169800","RBMY1F","ENST00000303766","GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0006397(mRNA processing);GO:0008380(RNA splicing);GO:0005634(nucleus);GO:0005515(protein binding);GO:0007283(spermatogenesis);GO:0042802(identical protein binding);GO:0005575(cellular_component)","NA","NA","NA","RNA binding motif protein, Y-linked, family 1, member F [Source:HGNC Symbol;Acc:HGNC:23974]",0,{"v":0.00427988495575221,"d":"0.00"},"-inf","-inf",1,1,"down","no"]
["ENSG00000221864","KRTAP12-2","ENST00000360770","GO:0005515(protein binding);GO:0005882(intermediate filament);GO:0045095(keratin filament);GO:0005829(cytosol);GO:0031424(keratinization)","NA","NA","NA","keratin associated protein 12-2 [Source:HGNC Symbol;Acc:HGNC:20530]",0,{"v":0.109069,"d":"0.11"},"-inf","-inf",1,1,"down","no"]
["ENSG00000176299","OR4M1","ENST00000315957","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0004930(G-protein coupled receptor activity);GO:0007186(G-protein coupled receptor signaling pathway);GO:0005886(plasma membrane);GO:0004871(signal transducer activity);GO:0007165(signal transduction);GO:0004984(olfactory receptor activity);GO:0007608(sensory perception of smell);GO:0050896(response to stimulus);GO:0050911(detection of chemical stimulus involved in sensory perception of smell);GO:0004888(transmembrane signaling receptor activity);GO:0050907(detection of chemical stimulus involved in sensory perception)","04740(Olfactory transduction)","K04257","NA","olfactory receptor family 4 subfamily M member 1 [Source:HGNC Symbol;Acc:HGNC:14735]",{"v":0.0144998149506347,"d":"0.01"},{"v":0.0257397765867419,"d":"0.03"},{"v":0.56332326357888,"d":"0.56"},{"v":-0.827965043056282,"d":"-0.83"},1,1,"down","no"]
["ENSG00000183496","MEX3B","ENST00000558133;ENST00000329713","GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0005509(calcium ion binding);GO:0000932(P-body);GO:0006468(protein phosphorylation);GO:0046777(protein autophosphorylation);GO:0046777(protein autophosphorylation)","NA","NA","NA","mex-3 RNA binding family member B [Source:HGNC Symbol;Acc:HGNC:25297]",{"v":0.0894003941338222,"d":"0.09"},{"v":0.146642858845096,"d":"0.15"},{"v":0.609647103431467,"d":"0.61"},{"v":-0.713953720170194,"d":"-0.71"},1,1,"down","no"]
["ENSG00000278616","BEND3P3","ENST00000611030","NA","NA","NA","NA","BEN domain containing 3 pseudogene 3 [Source:HGNC Symbol;Acc:HGNC:45016]",0,{"v":0.161616,"d":"0.16"},"-inf","-inf",1,1,"down","no"]
["ENSG00000249806","AC139720.1","ENST00000509497","NA","NA","NA","NA",null,{"v":0.053,"d":"0.05"},{"v":0.093267,"d":"0.09"},{"v":0.568261014077862,"d":"0.57"},{"v":-0.815374353149086,"d":"-0.82"},1,1,"down","no"]
["MSTRG.5368","AC104041.1","ENST00000560054;ENST00000560097","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["MSTRG.984","S100A1","ENST00000368698;ENST00000469893","GO:0046872(metal ion binding);GO:0005509(calcium ion binding);GO:0005515(protein binding);GO:0042802(identical protein binding);GO:0008016(regulation of heart contraction);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0042803(protein homodimerization activity);GO:0005576(extracellular region);GO:0048306(calcium-dependent protein binding);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:1901387(positive regulation of voltage-gated calcium channel activity);GO:0030018(Z disc);GO:0031430(M band);GO:0031672(A band);GO:0031674(I band);GO:0043005(neuron projection);GO:0016529(sarcoplasmic reticulum);GO:0043234(protein complex);GO:0021762(substantia nigra development);GO:0002224(toll-like receptor signaling pathway);GO:0035556(intracellular signal transduction);GO:0044548(S100 protein binding);GO:0051117(ATPase binding);GO:0051117(ATPase binding)","NA","NA","NA","S100 calcium binding protein A1 [Source:HGNC Symbol;Acc:HGNC:10486]",{"v":0.0237539062706271,"d":"0.02"},{"v":0.0501989412541254,"d":"0.05"},{"v":0.473195363830009,"d":"0.47"},{"v":-1.0794921560622,"d":"-1.08"},1,1,"down","no"]
["ENSG00000157322","CLEC18A","ENST00000568102;ENST00000565245;ENST00000615430","GO:0030246(carbohydrate binding);GO:0005794(Golgi apparatus);GO:0005783(endoplasmic reticulum);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0005615(extracellular space);GO:0005768(endosome);GO:0030247(polysaccharide binding);GO:0030247(polysaccharide binding)","NA","NA","NA","C-type lectin domain family 18 member A [Source:HGNC Symbol;Acc:HGNC:30388]",{"v":0.0920612052117264,"d":"0.09"},{"v":0.0871842964169381,"d":"0.09"},{"v":1.05593792684253,"d":"1.06"},{"v":0.078525028570827,"d":"0.08"},1,1,"up","no"]
["ENSG00000242208","RPL5P29","ENST00000482972","NA","NA","NA","NA","ribosomal protein L5 pseudogene 29 [Source:HGNC Symbol;Acc:HGNC:36335]",0,{"v":0.032321,"d":"0.03"},"-inf","-inf",1,1,"down","no"]
["ENSG00000257925","AC008083.1","ENST00000547748","NA","NA","NA","NA",null,{"v":0.049116,"d":"0.05"},0,"inf","inf",1,1,"up","no"]
["ENSG00000138685","FGF2","ENST00000608478;ENST00000264498;ENST00000614010","GO:0008083(growth factor activity);GO:0005576(extracellular region);GO:0005104(fibroblast growth factor receptor binding);GO:0008543(fibroblast growth factor receptor signaling pathway);GO:0060045(positive regulation of cardiac muscle cell proliferation);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0043537(negative regulation of blood vessel endothelial cell migration);GO:0043536(positive regulation of blood vessel endothelial cell migration);GO:0005634(nucleus);GO:0018108(peptidyl-tyrosine phosphorylation);GO:0043547(positive regulation of GTPase activity);GO:0005515(protein binding);GO:0007275(multicellular organism development);GO:0030154(cell differentiation);GO:0036092(phosphatidylinositol-3-phosphate biosynthetic process);GO:0030374(ligand-dependent nuclear receptor transcription coactivator activity);GO:0045893(positive regulation of transcription, DNA-templated);GO:0046854(phosphatidylinositol phosphorylation);GO:0014843(growth factor dependent regulation of skeletal muscle satellite cell proliferation);GO:0050918(positive chemotaxis);GO:0008201(heparin binding);GO:0000165(MAPK cascade);GO:0007399(nervous system development);GO:0001938(positive regulation of endothelial cell proliferation);GO:0006935(chemotaxis);GO:0007165(signal transduction);GO:0070374(positive regulation of ERK1 and ERK2 cascade);GO:0005615(extracellular space);GO:0046934(phosphatidylinositol-4,5-bisphosphate 3-kinase activity);GO:0014066(regulation of phosphatidylinositol 3-kinase signaling);GO:0038111(interleukin-7-mediated signaling pathway);GO:0048015(phosphatidylinositol-mediated signaling);GO:0005088(Ras guanyl-nucleotide exchange factor activity);GO:0016303(1-phosphatidylinositol-3-kinase activity);GO:0030198(extracellular matrix organization);GO:0001525(angiogenesis);GO:1903672(positive regulation of sprouting angiogenesis);GO:0005125(cytokine activity);GO:0004713(protein tyrosine kinase activity);GO:0009887(animal organ morphogenesis);GO:0010764(negative regulation of fibroblast migration);GO:0051781(positive regulation of cell division);GO:0002042(cell migration involved in sprouting angiogenesis);GO:0007265(Ras protein signal transduction);GO:0042060(wound healing);GO:0035019(somatic stem cell population maintenance);GO:2000546(positive regulation of endothelial cell chemotaxis to fibroblast growth factor);GO:0060548(negative regulation of cell death);GO:0030214(hyaluronan catabolic process);GO:0008284(positive regulation of cell proliferation);GO:0043406(positive regulation of MAP kinase activity);GO:0000187(activation of MAPK activity);GO:0001658(branching involved in ureteric bud morphogenesis);GO:0042056(chemoattractant activity);GO:2000544(regulation of endothelial cell chemotaxis to fibroblast growth factor);GO:0060591(chondroblast differentiation);GO:0090722(receptor-receptor interaction);GO:0006661(phosphatidylinositol biosynthetic process);GO:0010863(positive regulation of phospholipase C activity);GO:0032958(inositol phosphate biosynthetic process);GO:0042660(positive regulation of cell fate specification);GO:0043552(positive regulation of phosphatidylinositol 3-kinase activity);GO:0045765(regulation of angiogenesis);GO:0045766(positive regulation of angiogenesis);GO:0048598(embryonic morphogenesis);GO:0051209(release of sequestered calcium ion into cytosol);GO:0061045(negative regulation of wound healing);GO:0072089(stem cell proliferation);GO:0072089(stem cell proliferation)","04014(Ras signaling pathway);04015(Rap1 signaling pathway);04010(MAPK signaling pathway);04151(PI3K-Akt signaling pathway);04550(Signaling pathways regulating pluripotency of stem cells);04810(Regulation of actin cytoskeleton);05200(Pathways in cancer);05205(Proteoglycans in cancer);05226(Gastric cancer);05218(Melanoma);05224(Breast cancer);05167(Kaposi's sarcoma-associated herpesvirus infection);01521(EGFR tyrosine kinase inhibitor resistance);01521(EGFR tyrosine kinase inhibitor resistance)","K18497","NA","fibroblast growth factor 2 [Source:HGNC Symbol;Acc:HGNC:3676]",{"v":0.058117,"d":"0.06"},{"v":0.00633,"d":"0.01"},{"v":9.18120063191153,"d":"9.18"},{"v":3.19868282819712,"d":"3.20"},1,1,"up","no"]
["MSTRG.10505","AL022238.3","ENST00000609279","NA","NA","NA","NA",null,0,{"v":0.205977,"d":"0.21"},"-inf","-inf",1,1,"down","no"]
["ENSG00000125337","KIF25","ENST00000443060;ENST00000504593","GO:0010507(negative regulation of autophagy);GO:0005737(cytoplasm);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0003777(microtubule motor activity);GO:0005856(cytoskeleton);GO:0008017(microtubule binding);GO:0005874(microtubule);GO:0007018(microtubule-based movement);GO:0005813(centrosome);GO:0005815(microtubule organizing center);GO:0016887(ATPase activity);GO:0051289(protein homotetramerization);GO:0000070(mitotic sister chromatid segregation);GO:0005871(kinesin complex);GO:0006996(organelle organization);GO:0008569(ATP-dependent microtubule motor activity, minus-end-directed);GO:0046603(negative regulation of mitotic centrosome separation);GO:0051294(establishment of spindle orientation);GO:0051647(nucleus localization);GO:0051647(nucleus localization)","NA","NA","NA","kinesin family member 25 [Source:HGNC Symbol;Acc:HGNC:6390]",{"v":0.0568947057561673,"d":"0.06"},{"v":0.0283996417590275,"d":"0.03"},{"v":2.00335998034489,"d":"2.00"},{"v":1.00242167986044,"d":"1.00"},1,1,"up","no"]
["ENSG00000229589","ACVR2B-AS1","ENST00000441531","NA","NA","NA","NA","ACVR2B antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:44161]",{"v":0.09503,"d":"0.10"},{"v":0.03154,"d":"0.03"},{"v":3.01299936588459,"d":"3.01"},{"v":1.59120036930302,"d":"1.59"},1,1,"up","no"]
["ENSG00000096092","TMEM14A","ENST00000211314","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005515(protein binding)","NA","NA","NA","transmembrane protein 14A [Source:HGNC Symbol;Acc:HGNC:21076]",{"v":0.526024,"d":"0.53"},{"v":0.539407,"d":"0.54"},{"v":0.975189420975256,"d":"0.98"},{"v":-0.0362456194515086,"d":"-0.04"},1,1,"down","no"]
["ENSG00000144935","TRPC1","ENST00000612385;ENST00000273482;ENST00000480101;ENST00000460401","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0055085(transmembrane transport);GO:0005216(ion channel activity);GO:0006811(ion transport);GO:0005515(protein binding);GO:0006816(calcium ion transport);GO:0070588(calcium ion transmembrane transport);GO:0005262(calcium channel activity);GO:0005886(plasma membrane);GO:0005887(integral component of plasma membrane);GO:1903779(regulation of cardiac conduction);GO:0043235(receptor complex);GO:0051281(positive regulation of release of sequestered calcium ion into cytosol);GO:0051480(regulation of cytosolic calcium ion concentration);GO:0051592(response to calcium ion);GO:0042438(melanin biosynthetic process);GO:0005261(cation channel activity);GO:0015279(store-operated calcium channel activity);GO:0070679(inositol 1,4,5 trisphosphate binding);GO:0006828(manganese ion transport);GO:0006828(manganese ion transport)","04972(Pancreatic secretion);04724(Glutamatergic synapse);04726(Serotonergic synapse);04360(Axon guidance);04360(Axon guidance)","K04964","NA","transient receptor potential cation channel subfamily C member 1 [Source:HGNC Symbol;Acc:HGNC:12333]",{"v":0.138064182885906,"d":"0.14"},{"v":0.101819442323826,"d":"0.10"},{"v":1.35597072361492,"d":"1.36"},{"v":0.439326029984929,"d":"0.44"},1,1,"up","no"]
["ENSG00000161281","COX7A1","ENST00000481297;ENST00000292907","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005743(mitochondrial inner membrane);GO:0005739(mitochondrion);GO:1902600(hydrogen ion transmembrane transport);GO:0004129(cytochrome-c oxidase activity);GO:0009055(electron carrier activity);GO:0005746(mitochondrial respiratory chain);GO:0006091(generation of precursor metabolites and energy);GO:0006091(generation of precursor metabolites and energy)","00190(Oxidative phosphorylation);04260(Cardiac muscle contraction);05010(Alzheimer's disease);05012(Parkinson's disease);05016(Huntington's disease);04932(Non-alcoholic fatty liver disease (NAFLD));04932(Non-alcoholic fatty liver disease (NAFLD))","K02270","NA","cytochrome c oxidase subunit 7A1 [Source:HGNC Symbol;Acc:HGNC:2287]",{"v":0.0160103320079523,"d":"0.02"},{"v":0.0216175109343936,"d":"0.02"},{"v":0.740618661257608,"d":"0.74"},{"v":-0.433197193548729,"d":"-0.43"},1,1,"down","no"]
["ENSG00000224163","AC025594.1","ENST00000469533","NA","NA","NA","NA",null,{"v":0.019266,"d":"0.02"},{"v":0.101503,"d":"0.10"},{"v":0.189807197816813,"d":"0.19"},{"v":-2.39739339200292,"d":"-2.40"},1,1,"down","no"]
["ENSG00000203855","HSD3BP4","ENST00000511509","NA","NA","NA","NA","hydroxy-delta-5-steroid dehydrogenase, 3 beta, pseudogene 4 [Source:HGNC Symbol;Acc:HGNC:5222]",0,0,1,0,1,1,"no","no"]
["MSTRG.5464","AC140725.1","ENST00000559045","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000239389","PCDHA13","ENST00000617769","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005509(calcium ion binding);GO:0007155(cell adhesion);GO:0007156(homophilic cell adhesion via plasma membrane adhesion molecules);GO:0005886(plasma membrane);GO:0005887(integral component of plasma membrane);GO:0007399(nervous system development);GO:0007267(cell-cell signaling)","NA","NA","NA","protocadherin alpha 13 [Source:HGNC Symbol;Acc:HGNC:8667]",{"v":0.0370586671647366,"d":"0.04"},{"v":0.087884689017557,"d":"0.09"},{"v":0.421673758865248,"d":"0.42"},{"v":-1.24580085067823,"d":"-1.25"},1,1,"down","no"]
["ENSG00000102452","NALCN","ENST00000251127","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0055085(transmembrane transport);GO:0005216(ion channel activity);GO:0006811(ion transport);GO:0034220(ion transmembrane transport);GO:0098655(cation transmembrane transport);GO:0005244(voltage-gated ion channel activity);GO:0034765(regulation of ion transmembrane transport);GO:0071805(potassium ion transmembrane transport);GO:0005515(protein binding);GO:0006814(sodium ion transport);GO:0070588(calcium ion transmembrane transport);GO:0005261(cation channel activity);GO:0005886(plasma membrane);GO:0005272(sodium channel activity);GO:0035725(sodium ion transmembrane transport);GO:0060075(regulation of resting membrane potential);GO:0086010(membrane depolarization during action potential);GO:0006816(calcium ion transport);GO:0022840(leak channel activity)","NA","NA","NA","sodium leak channel, non-selective [Source:HGNC Symbol;Acc:HGNC:19082]",{"v":0.00725902580717238,"d":"0.01"},{"v":0.00940474203999553,"d":"0.01"},{"v":0.771847412326881,"d":"0.77"},{"v":-0.373612427753502,"d":"-0.37"},1,1,"down","no"]
["ENSG00000144962","SPATA16","ENST00000351008","GO:0005794(Golgi apparatus);GO:0007275(multicellular organism development);GO:0030154(cell differentiation);GO:0007283(spermatogenesis)","NA","NA","NA","spermatogenesis associated 16 [Source:HGNC Symbol;Acc:HGNC:29935]",{"v":0.024407,"d":"0.02"},0,"inf","inf",1,1,"up","no"]
["ENSG00000124143","ARHGAP40","ENST00000373345","GO:0007165(signal transduction);GO:0043547(positive regulation of GTPase activity);GO:0005096(GTPase activator activity);GO:0005829(cytosol);GO:0051056(regulation of small GTPase mediated signal transduction)","NA","NA","NA","Rho GTPase activating protein 40 [Source:HGNC Symbol;Acc:HGNC:16226]",{"v":0.0113222075117371,"d":"0.01"},{"v":0.0802895943661972,"d":"0.08"},{"v":0.141017121846413,"d":"0.14"},{"v":-2.82605775422602,"d":"-2.83"},1,1,"down","no"]
["ENSG00000240023","AL133163.1","ENST00000459899","NA","NA","NA","NA",null,0,{"v":0.036538,"d":"0.04"},"-inf","-inf",1,1,"down","no"]
["MSTRG.11684","LINC02469","ENST00000506460","NA","NA","NA","NA","long intergenic non-protein coding RNA 2469 [Source:HGNC Symbol;Acc:HGNC:53408]",{"v":0.714033,"d":"0.71"},{"v":0.061571,"d":"0.06"},{"v":11.5969043868055,"d":"11.60"},{"v":3.5356678466351,"d":"3.54"},1,1,"up","no"]
["ENSG00000183072","NKX2-5","ENST00000329198","GO:0008284(positive regulation of cell proliferation);GO:0010667(negative regulation of cardiac muscle cell apoptotic process);GO:1903779(regulation of cardiac conduction);GO:0010832(negative regulation of myotube differentiation);GO:0043066(negative regulation of apoptotic process);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0060412(ventricular septum morphogenesis);GO:0090090(negative regulation of canonical Wnt signaling pathway);GO:0005634(nucleus);GO:0006355(regulation of transcription, DNA-templated);GO:0006366(transcription from RNA polymerase II promoter);GO:0003677(DNA binding);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0043565(sequence-specific DNA binding);GO:0005515(protein binding);GO:0007275(multicellular organism development);GO:0045893(positive regulation of transcription, DNA-templated);GO:0007507(heart development);GO:0001104(RNA polymerase II transcription cofactor activity);GO:0001190(transcriptional activator activity, RNA polymerase II transcription factor binding);GO:0001228(transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding);GO:0003682(chromatin binding);GO:0003705(transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding);GO:0010736(serum response element binding);GO:0042803(protein homodimerization activity);GO:0046982(protein heterodimerization activity);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0001570(vasculogenesis);GO:0001947(heart looping);GO:0003007(heart morphogenesis);GO:0003151(outflow tract morphogenesis);GO:0003161(cardiac conduction system development);GO:0003162(atrioventricular node development);GO:0003166(bundle of His development);GO:0003168(Purkinje myocyte differentiation);GO:0003208(cardiac ventricle morphogenesis);GO:0003211(cardiac ventricle formation);GO:0003222(ventricular trabecula myocardium morphogenesis);GO:0003278(apoptotic process involved in heart morphogenesis);GO:0003342(proepicardium development);GO:0003350(pulmonary myocardium development);GO:0007512(adult heart development);GO:0010628(positive regulation of gene expression);GO:0010735(positive regulation of transcription via serum response element binding);GO:0010765(positive regulation of sodium ion transport);GO:0030097(hemopoiesis);GO:0030154(cell differentiation);GO:0030509(BMP signaling pathway);GO:0030878(thyroid gland development);GO:0035050(embryonic heart tube development);GO:0045214(sarcomere organization);GO:0045823(positive regulation of heart contraction);GO:0048536(spleen development);GO:0048738(cardiac muscle tissue development);GO:0051891(positive regulation of cardioblast differentiation);GO:0055005(ventricular cardiac myofibril assembly);GO:0055007(cardiac muscle cell differentiation);GO:0055117(regulation of cardiac muscle contraction);GO:0060037(pharyngeal system development);GO:0060038(cardiac muscle cell proliferation);GO:0060043(regulation of cardiac muscle cell proliferation);GO:0060047(heart contraction);GO:0060048(cardiac muscle contraction);GO:0060070(canonical Wnt signaling pathway);GO:0060261(positive regulation of transcription initiation from RNA polymerase II promoter);GO:0060347(heart trabecula formation);GO:0060928(atrioventricular node cell development);GO:0060929(atrioventricular node cell fate commitment);GO:0060971(embryonic heart tube left/right pattern formation);GO:0072358(cardiovascular system development);GO:0005667(transcription factor complex);GO:0005737(cytoplasm);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:0055014(atrial cardiac muscle cell development);GO:0055015(ventricular cardiac muscle cell development);GO:0045892(negative regulation of transcription, DNA-templated);GO:0044212(transcription regulatory region DNA binding);GO:0090575(RNA polymerase II transcription factor complex);GO:0001077(transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0055008(cardiac muscle tissue morphogenesis);GO:0003148(outflow tract septum morphogenesis);GO:0032993(protein-DNA complex);GO:0008134(transcription factor binding);GO:0032991(macromolecular complex);GO:0045666(positive regulation of neuron differentiation);GO:0060413(atrial septum morphogenesis);GO:0003221(right ventricular cardiac muscle tissue morphogenesis);GO:0003285(septum secundum development)","NA","NA","NA","NK2 homeobox 5 [Source:HGNC Symbol;Acc:HGNC:2488]",{"v":0.0659401408787011,"d":"0.07"},{"v":0.0366039398280802,"d":"0.04"},{"v":1.80144927536232,"d":"1.80"},{"v":0.849158029386956,"d":"0.85"},1,1,"up","no"]
["MSTRG.9066","AC110769.2","ENST00000602760","NA","NA","NA","NA",null,{"v":0.252583,"d":"0.25"},{"v":0.029374,"d":"0.03"},{"v":8.59886294001498,"d":"8.60"},{"v":3.10414589943602,"d":"3.10"},1,1,"up","no"]
["ENSG00000198678","AC089987.2","ENST00000328207","NA","NA","NA","NA",null,{"v":0.054368,"d":"0.05"},{"v":0.067627,"d":"0.07"},{"v":0.803939255031274,"d":"0.80"},{"v":-0.314841598179582,"d":"-0.31"},1,1,"down","no"]
["ENSG00000011083","SLC6A7","ENST00000524041;ENST00000230671","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0015293(symporter activity);GO:0005328(neurotransmitter:sodium symporter activity);GO:0006836(neurotransmitter transport);GO:0005886(plasma membrane);GO:0006865(amino acid transport);GO:0005887(integral component of plasma membrane);GO:0015193(L-proline transmembrane transporter activity);GO:0005298(proline:sodium symporter activity);GO:0015824(proline transport);GO:0035524(proline transmembrane transport);GO:0055085(transmembrane transport);GO:0055085(transmembrane transport)","NA","NA","NA","solute carrier family 6 member 7 [Source:HGNC Symbol;Acc:HGNC:11054]",{"v":0.0156806668184924,"d":"0.02"},{"v":0.00795059052607607,"d":"0.01"},{"v":1.97226442074504,"d":"1.97"},{"v":0.97985298626151,"d":"0.98"},1,1,"up","no"]
["ENSG00000132563","REEP2","ENST00000378339;ENST00000504163","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005783(endoplasmic reticulum);GO:0070062(extracellular exosome);GO:0031883(taste receptor binding);GO:0032386(regulation of intracellular transport);GO:0032596(protein transport into membrane raft);GO:0050913(sensory perception of bitter taste);GO:0050916(sensory perception of sweet taste);GO:0005789(endoplasmic reticulum membrane);GO:0005887(integral component of plasma membrane);GO:0005881(cytoplasmic microtubule);GO:0071786(endoplasmic reticulum tubular network organization);GO:0071786(endoplasmic reticulum tubular network organization)","NA","NA","NA","receptor accessory protein 2 [Source:HGNC Symbol;Acc:HGNC:17975]",{"v":0.0206612545676005,"d":"0.02"},{"v":0.0432063915956151,"d":"0.04"},{"v":0.478199030388304,"d":"0.48"},{"v":-1.06431689008961,"d":"-1.06"},1,1,"down","no"]
["ENSG00000131484","AC091132.1","ENST00000588189","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["MSTRG.1491","TGIF2P1","ENST00000435390","NA","NA","NA","NA","TGFB induced factor homeobox 2 pseudogene 1 [Source:HGNC Symbol;Acc:HGNC:33317]",0,{"v":0.060388,"d":"0.06"},"-inf","-inf",1,1,"down","no"]
["ENSG00000255029","AC110058.1","ENST00000530389","NA","NA","NA","NA",null,0,{"v":0.075365,"d":"0.08"},"-inf","-inf",1,1,"down","no"]
["MSTRG.12529","AC008680.1","ENST00000523398","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000185031","SLC2A3P2","ENST00000331747","NA","NA","NA","NA","solute carrier family 2 member 3 pseudogene 2 [Source:HGNC Symbol;Acc:HGNC:31074]",{"v":0.034731,"d":"0.03"},0,"inf","inf",1,1,"up","no"]
["ENSG00000225398","PGM5P4","ENST00000421970","NA","NA","NA","NA","phosphoglucomutase 5 pseudogene 4 [Source:HGNC Symbol;Acc:HGNC:49605]",0,{"v":0.030514,"d":"0.03"},"-inf","-inf",1,1,"down","no"]
["ENSG00000264451","AC036222.1","ENST00000579972","NA","NA","NA","NA",null,{"v":0.21998,"d":"0.22"},0,"inf","inf",1,1,"up","no"]
["ENSG00000214249","CTAGE11P","ENST00000451540","NA","NA","NA","NA","CTAGE family member 11, pseudogene [Source:HGNC Symbol;Acc:HGNC:37293]",{"v":0.021845,"d":"0.02"},0,"inf","inf",1,1,"up","no"]
["ENSG00000144115","THNSL2","ENST00000449349;ENST00000496844;ENST00000464022;ENST00000324166;ENST00000377254;ENST00000476349;ENST00000343544","GO:0016829(lyase activity);GO:0005576(extracellular region);GO:0005125(cytokine activity);GO:0005615(extracellular space);GO:0003674(molecular_function);GO:0008150(biological_process);GO:0005575(cellular_component);GO:0030170(pyridoxal phosphate binding);GO:0070905(serine binding);GO:0016311(dephosphorylation);GO:0009071(serine family amino acid catabolic process);GO:0046360(2-oxobutyrate biosynthetic process);GO:0046360(2-oxobutyrate biosynthetic process)","NA","NA","NA","threonine synthase like 2 [Source:HGNC Symbol;Acc:HGNC:25602]",{"v":0.0426083590421396,"d":"0.04"},{"v":0.00709430057533821,"d":"0.01"},{"v":6.00599856034551,"d":"6.01"},{"v":2.58640412907711,"d":"2.59"},1,1,"up","no"]
["ENSG00000175619","OR4B1","ENST00000309562","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0004930(G-protein coupled receptor activity);GO:0007186(G-protein coupled receptor signaling pathway);GO:0005886(plasma membrane);GO:0004871(signal transducer activity);GO:0007165(signal transduction);GO:0004984(olfactory receptor activity);GO:0007608(sensory perception of smell);GO:0050896(response to stimulus);GO:0050911(detection of chemical stimulus involved in sensory perception of smell);GO:0004888(transmembrane signaling receptor activity);GO:0050907(detection of chemical stimulus involved in sensory perception)","04740(Olfactory transduction)","K04257","NA","olfactory receptor family 4 subfamily B member 1 [Source:HGNC Symbol;Acc:HGNC:8290]",{"v":0.055271,"d":"0.06"},{"v":0.049058,"d":"0.05"},{"v":1.12664601084431,"d":"1.13"},{"v":0.172034295793116,"d":"0.17"},1,1,"up","no"]
["MSTRG.1025","CKS1B","ENST00000368436;ENST00000477676;ENST00000471245;ENST00000474215;ENST00000308987;ENST00000368439","GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0051301(cell division);GO:0045859(regulation of protein kinase activity);GO:0007049(cell cycle);GO:0016538(cyclin-dependent protein serine/threonine kinase regulator activity);GO:0005515(protein binding);GO:0005654(nucleoplasm);GO:0019901(protein kinase binding);GO:0019005(SCF ubiquitin ligase complex);GO:0043130(ubiquitin binding);GO:0045893(positive regulation of transcription, DNA-templated);GO:0007346(regulation of mitotic cell cycle);GO:0042393(histone binding);GO:0045737(positive regulation of cyclin-dependent protein serine/threonine kinase activity);GO:0000307(cyclin-dependent protein kinase holoenzyme complex);GO:0061575(cyclin-dependent protein serine/threonine kinase activator activity);GO:0061575(cyclin-dependent protein serine/threonine kinase activator activity)","05200(Pathways in cancer);05222(Small cell lung cancer);05222(Small cell lung cancer)","K02219","NA","CDC28 protein kinase regulatory subunit 1B [Source:HGNC Symbol;Acc:HGNC:19083]",{"v":0.341781294696322,"d":"0.34"},{"v":0.237007908896493,"d":"0.24"},{"v":1.44206704446131,"d":"1.44"},{"v":0.528138239796047,"d":"0.53"},1,1,"up","no"]
["MSTRG.397","GJA4","ENST00000342280","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0005921(gap junction);GO:0030054(cell junction);GO:0007154(cell communication);GO:0005922(connexin complex);GO:0006810(transport);GO:0005887(integral component of plasma membrane);GO:0001568(blood vessel development);GO:0003158(endothelium development);GO:0006816(calcium ion transport);GO:0007043(cell-cell junction assembly);GO:0007267(cell-cell signaling);GO:0048265(response to pain)","NA","NA","NA","gap junction protein alpha 4 [Source:HGNC Symbol;Acc:HGNC:4278]",{"v":0.233310104834013,"d":"0.23"},{"v":0.0531434082702388,"d":"0.05"},{"v":4.39019837883959,"d":"4.39"},{"v":2.13428613194783,"d":"2.13"},1,1,"up","no"]
["ENSG00000236699","ARHGEF38","ENST00000510406;ENST00000420470;ENST00000503289","GO:0005737(cytoplasm);GO:0005089(Rho guanyl-nucleotide exchange factor activity);GO:0035023(regulation of Rho protein signal transduction);GO:0005085(guanyl-nucleotide exchange factor activity);GO:0043547(positive regulation of GTPase activity);GO:0007264(small GTPase mediated signal transduction);GO:0007264(small GTPase mediated signal transduction)","NA","NA","NA","Rho guanine nucleotide exchange factor 38 [Source:HGNC Symbol;Acc:HGNC:25968]",{"v":3.79815437392796E-3,"d":"0.00"},0,"inf","inf",1,1,"up","no"]
["ENSG00000228058","LINC01736","ENST00000445339","NA","NA","NA","NA","long intergenic non-protein coding RNA 1736 [Source:HGNC Symbol;Acc:HGNC:52524]",0,{"v":0.231481,"d":"0.23"},"-inf","-inf",1,1,"down","no"]
["ENSG00000157654","PALM2-AKAP2","ENST00000374530","GO:0016020(membrane);GO:0008360(regulation of cell shape)","NA","NA","NA","PALM2-AKAP2 readthrough [Source:HGNC Symbol;Acc:HGNC:33529]",{"v":0.00185776057539924,"d":"0.00"},0,"inf","inf",1,1,"up","no"]
["MSTRG.2997","DDX11L8","ENST00000535849","NA","NA","NA","NA","DEAD/H-box helicase 11 like 8 [Source:HGNC Symbol;Acc:HGNC:37101]",{"v":0.602902,"d":"0.60"},{"v":0.312634,"d":"0.31"},{"v":1.92845947657644,"d":"1.93"},{"v":0.947448830407198,"d":"0.95"},1,1,"up","no"]
["ENSG00000011332","DPF1","ENST00000488378;ENST00000614244;ENST00000473716","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0007399(nervous system development);GO:0006915(apoptotic process);GO:0071565(nBAF complex);GO:0003676(nucleic acid binding);GO:0003676(nucleic acid binding)","05225(Hepatocellular carcinoma);05225(Hepatocellular carcinoma)","K22198","NA","double PHD fingers 1 [Source:HGNC Symbol;Acc:HGNC:20225]",{"v":0.0449085702083333,"d":"0.04"},0,"inf","inf",1,1,"up","no"]
["ENSG00000113657","DPYSL3","ENST00000343218","GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0016787(hydrolase activity);GO:0042995(cell projection);GO:0005515(protein binding);GO:0016810(hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds);GO:0005615(extracellular space);GO:0051017(actin filament bundle assembly);GO:0030334(regulation of cell migration);GO:0010975(regulation of neuron projection development);GO:0048678(response to axon injury);GO:0051491(positive regulation of filopodium assembly);GO:0030027(lamellipodium);GO:0030426(growth cone);GO:0031941(filamentous actin);GO:0017124(SH3 domain binding);GO:0035374(chondroitin sulfate binding);GO:0031005(filamin binding);GO:0030336(negative regulation of cell migration);GO:0051260(protein homooligomerization);GO:0010976(positive regulation of neuron projection development);GO:0010977(negative regulation of neuron projection development);GO:0071345(cellular response to cytokine stimulus);GO:0070382(exocytic vesicle);GO:0044297(cell body);GO:0051764(actin crosslink formation);GO:0048666(neuron development)","NA","NA","NA","dihydropyrimidinase like 3 [Source:HGNC Symbol;Acc:HGNC:3015]",{"v":0.0869410547180346,"d":"0.09"},{"v":0.00598660413176996,"d":"0.01"},{"v":14.5225995914198,"d":"14.52"},{"v":3.86022781832856,"d":"3.86"},1,1,"up","no"]
["ENSG00000111732","AICDA","ENST00000545576;ENST00000229335","GO:0006397(mRNA processing);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0016787(hydrolase activity);GO:0003824(catalytic activity);GO:0005515(protein binding);GO:0016814(hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines);GO:0031625(ubiquitin protein ligase binding);GO:0080111(DNA demethylation);GO:0016446(somatic hypermutation of immunoglobulin genes);GO:0030183(B cell differentiation);GO:0004126(cytidine deaminase activity);GO:0090310(negative regulation of methylation-dependent chromatin silencing);GO:0000178(exosome (RNase complex));GO:0009972(cytidine deamination);GO:0042742(defense response to bacterium);GO:0045190(isotype switching);GO:0071222(cellular response to lipopolysaccharide);GO:0016445(somatic diversification of immunoglobulins);GO:0016445(somatic diversification of immunoglobulins)","04672(Intestinal immune network for IgA production);05340(Primary immunodeficiency);05340(Primary immunodeficiency)","K10989","EC:3.5.4.38","activation induced cytidine deaminase [Source:HGNC Symbol;Acc:HGNC:13203]",{"v":0.00952668154093098,"d":"0.01"},{"v":0.0146465136436597,"d":"0.01"},{"v":0.650440218929162,"d":"0.65"},{"v":-0.620511627979164,"d":"-0.62"},1,1,"down","no"]
["ENSG00000241861","GAPDHP50","ENST00000464421","NA","NA","NA","NA","glyceraldehyde 3 phosphate dehydrogenase pseudogene 50 [Source:HGNC Symbol;Acc:HGNC:38556]",0,{"v":0.137224,"d":"0.14"},"-inf","-inf",1,1,"down","no"]
["ENSG00000275410","HNF1B","ENST00000617811","GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0045893(positive regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0005515(protein binding);GO:0000977(RNA polymerase II regulatory region sequence-specific DNA binding);GO:0001822(kidney development);GO:0060261(positive regulation of transcription initiation from RNA polymerase II promoter);GO:0001159(core promoter proximal region DNA binding);GO:0003705(transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding);GO:0032403(protein complex binding);GO:0042803(protein homodimerization activity);GO:0043565(sequence-specific DNA binding);GO:0044212(transcription regulatory region DNA binding);GO:0046982(protein heterodimerization activity);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0001714(endodermal cell fate specification);GO:0001826(inner cell mass cell differentiation);GO:0001889(liver development);GO:0007219(Notch signaling pathway);GO:0007492(endoderm development);GO:0009743(response to carbohydrate);GO:0009749(response to glucose);GO:0009952(anterior/posterior pattern specification);GO:0010628(positive regulation of gene expression);GO:0014070(response to organic cyclic compound);GO:0030073(insulin secretion);GO:0030111(regulation of Wnt signaling pathway);GO:0030902(hindbrain development);GO:0032922(circadian regulation of gene expression);GO:0035565(regulation of pronephros size);GO:0039020(pronephric nephron tubule development);GO:0042493(response to drug);GO:0042663(regulation of endodermal cell fate specification);GO:0043066(negative regulation of apoptotic process);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0048557(embryonic digestive tract morphogenesis);GO:0048598(embryonic morphogenesis);GO:0048754(branching morphogenesis of an epithelial tube);GO:0048793(pronephros development);GO:0050673(epithelial cell proliferation);GO:0060429(epithelium development);GO:0060677(ureteric bud elongation);GO:0060993(kidney morphogenesis);GO:0061017(hepatoblast differentiation);GO:0061296(negative regulation of mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis);GO:0065004(protein-DNA complex assembly);GO:0070365(hepatocyte differentiation);GO:0072095(regulation of branch elongation involved in ureteric bud branching);GO:0072164(mesonephric tubule development);GO:0072176(nephric duct development);GO:0072177(mesonephric duct development);GO:0072179(nephric duct formation);GO:0072181(mesonephric duct formation);GO:1900212(negative regulation of mesenchymal cell apoptotic process involved in metanephros development);GO:0005667(transcription factor complex)","04950(Maturity onset diabetes of the young)","K08034","NA","HNF1 homeobox B [Source:HGNC Symbol;Acc:HGNC:11630]",{"v":0.0186609265347199,"d":"0.02"},{"v":0.00687026886950688,"d":"0.01"},{"v":2.71618576931463,"d":"2.72"},{"v":1.44158215384765,"d":"1.44"},1,1,"up","no"]
["ENSG00000260978","AC126407.1","ENST00000563044","NA","NA","NA","NA",null,{"v":0.021796,"d":"0.02"},0,"inf","inf",1,1,"up","no"]
["ENSG00000133958","UNC79","ENST00000553484;ENST00000256339","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005886(plasma membrane);GO:0034220(ion transmembrane transport);GO:0030534(adult behavior);GO:0035264(multicellular organism growth);GO:0048149(behavioral response to ethanol);GO:0048149(behavioral response to ethanol)","NA","NA","NA","unc-79 homolog, NALCN channel complex subunit [Source:HGNC Symbol;Acc:HGNC:19966]",{"v":0.0368919523695357,"d":"0.04"},{"v":0.0139019899304723,"d":"0.01"},{"v":2.65371738535581,"d":"2.65"},{"v":1.40801473526882,"d":"1.41"},1,1,"up","no"]
["ENSG00000280039","RN7SKP23","ENST00000625159","NA","NA","NA","NA","RNA, 7SK small nuclear pseudogene 23 [Source:HGNC Symbol;Acc:HGNC:45747]",{"v":0.035854,"d":"0.04"},0,"inf","inf",1,1,"up","no"]
["ENSG00000166407","LMO1","ENST00000335790;ENST00000428101","GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0005515(protein binding);GO:0005654(nucleoplasm);GO:1902036(regulation of hematopoietic stem cell differentiation);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0046013(regulation of T cell homeostatic proliferation);GO:0046013(regulation of T cell homeostatic proliferation)","NA","NA","NA","LIM domain only 1 [Source:HGNC Symbol;Acc:HGNC:6641]",{"v":0.0267825627218935,"d":"0.03"},{"v":0.0493990071005917,"d":"0.05"},{"v":0.542168037251354,"d":"0.54"},{"v":-0.883188031247309,"d":"-0.88"},1,1,"down","no"]
["ENSG00000214360","EFCAB9","ENST00000398186","GO:0005509(calcium ion binding)","NA","NA","NA","EF-hand calcium binding domain 9 [Source:HGNC Symbol;Acc:HGNC:34530]",0,0,1,0,1,1,"no","no"]
["MSTRG.14604","AC040970.1","ENST00000520885;ENST00000517908","NA","NA","NA","NA",null,0,{"v":0.0306852986369269,"d":"0.03"},"-inf","-inf",1,1,"down","no"]
["MSTRG.14469","AC087752.3","ENST00000523905","NA","NA","NA","NA",null,{"v":0.068578,"d":"0.07"},{"v":0.193049,"d":"0.19"},{"v":0.355236235359935,"d":"0.36"},{"v":-1.49314934566614,"d":"-1.49"},1,1,"down","no"]
["ENSG00000235376","RPEL1","ENST00000441178","GO:0046872(metal ion binding);GO:0016853(isomerase activity);GO:0003824(catalytic activity);GO:0008152(metabolic process);GO:0005975(carbohydrate metabolic process);GO:0006098(pentose-phosphate shunt);GO:0005829(cytosol);GO:0016857(racemase and epimerase activity, acting on carbohydrates and derivatives);GO:0004750(ribulose-phosphate 3-epimerase activity);GO:0009052(pentose-phosphate shunt, non-oxidative branch);GO:0019323(pentose catabolic process);GO:0044262(cellular carbohydrate metabolic process)","00030(Pentose phosphate pathway);00040(Pentose and glucuronate interconversions)","K01783","EC:5.1.3.1","ribulose-5-phosphate-3-epimerase like 1 [Source:HGNC Symbol;Acc:HGNC:45241]",0,0,1,0,1,1,"no","no"]
["ENSG00000165685","TMEM52B","ENST00000546153;ENST00000381923;ENST00000298530","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0003674(molecular_function);GO:0008150(biological_process);GO:0070062(extracellular exosome);GO:0070062(extracellular exosome)","NA","NA","NA","transmembrane protein 52B [Source:HGNC Symbol;Acc:HGNC:26438]",{"v":0.00471439380911436,"d":"0.00"},{"v":0.0356998245915735,"d":"0.04"},{"v":0.132056497841368,"d":"0.13"},{"v":-2.92077280381112,"d":"-2.92"},1,1,"down","no"]
["ENSG00000087076","HSD17B14","ENST00000263278","GO:0005737(cytoplasm);GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0006629(lipid metabolic process);GO:0008202(steroid metabolic process);GO:0005515(protein binding);GO:0042802(identical protein binding);GO:0005829(cytosol);GO:0004303(estradiol 17-beta-dehydrogenase activity);GO:0006703(estrogen biosynthetic process);GO:0047045(testosterone 17-beta-dehydrogenase (NADP+) activity);GO:0006706(steroid catabolic process)","NA","NA","NA","hydroxysteroid 17-beta dehydrogenase 14 [Source:HGNC Symbol;Acc:HGNC:23238]",{"v":0.20287543793911,"d":"0.20"},{"v":0.270833036690086,"d":"0.27"},{"v":0.749079360548101,"d":"0.75"},{"v":-0.416809523060425,"d":"-0.42"},1,1,"down","no"]
["MSTRG.6156","AC009139.2","ENST00000569032","NA","NA","NA","NA",null,0,{"v":0.082987,"d":"0.08"},"-inf","-inf",1,1,"down","no"]
["MSTRG.3936","UBE2L5P","ENST00000436446","GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0061631(ubiquitin conjugating enzyme activity);GO:0042787(protein ubiquitination involved in ubiquitin-dependent protein catabolic process)","NA","NA","NA","ubiquitin conjugating enzyme E2 L5, pseudogene [Source:HGNC Symbol;Acc:HGNC:13477]",0,{"v":0.0386488511029412,"d":"0.04"},"-inf","-inf",1,1,"down","no"]
["ENSG00000168754","FAM178B","ENST00000490605","NA","NA","NA","NA","family with sequence similarity 178 member B [Source:HGNC Symbol;Acc:HGNC:28036]",{"v":0.120100014104372,"d":"0.12"},{"v":0.0841957630465444,"d":"0.08"},{"v":1.42643774174217,"d":"1.43"},{"v":0.512416780470334,"d":"0.51"},1,1,"up","no"]
["ENSG00000259666","LINGO1-AS1","ENST00000558691","NA","NA","NA","NA","LINGO1 antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:27368]",0,{"v":0.00964275,"d":"0.01"},"-inf","-inf",1,1,"down","no"]
["MSTRG.14288","AC026979.3","ENST00000607315","NA","NA","NA","NA",null,{"v":0.637742,"d":"0.64"},0,"inf","inf",1,1,"up","no"]
["MSTRG.5701","AF001548.2","ENST00000574212","NA","NA","NA","NA",null,{"v":0.134388,"d":"0.13"},{"v":0.112141,"d":"0.11"},{"v":1.1983841770628,"d":"1.20"},{"v":0.26109048032475,"d":"0.26"},1,1,"up","no"]
["ENSG00000259986","AC103876.1","ENST00000561498","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000128714","HOXD13","ENST00000392539","GO:0005634(nucleus);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0043565(sequence-specific DNA binding);GO:0007275(multicellular organism development);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0006366(transcription from RNA polymerase II promoter);GO:0001501(skeletal system development);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:0001077(transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0001158(enhancer sequence-specific DNA binding);GO:0001228(transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding);GO:0003682(chromatin binding);GO:1990837(sequence-specific double-stranded DNA binding);GO:0007389(pattern specification process);GO:0009952(anterior/posterior pattern specification);GO:0022612(gland morphogenesis);GO:0030326(embryonic limb morphogenesis);GO:0030539(male genitalia development);GO:0030850(prostate gland development);GO:0033574(response to testosterone);GO:0035108(limb morphogenesis);GO:0042127(regulation of cell proliferation);GO:0042733(embryonic digit morphogenesis);GO:0048619(embryonic hindgut morphogenesis);GO:0060527(prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis);GO:0060571(morphogenesis of an epithelial fold);GO:0060602(branch elongation of an epithelium);GO:0060687(regulation of branching involved in prostate gland morphogenesis)","NA","NA","NA","homeobox D13 [Source:HGNC Symbol;Acc:HGNC:5136]",{"v":0.044518,"d":"0.04"},0,"inf","inf",1,1,"up","no"]
["ENSG00000156970","BUB1B","ENST00000287598;ENST00000560120;ENST00000558151;ENST00000558972","GO:0048471(perinuclear region of cytoplasm);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0005829(cytosol);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0051301(cell division);GO:0005694(chromosome);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0007049(cell cycle);GO:0006915(apoptotic process);GO:0005815(microtubule organizing center);GO:0000775(chromosome, centromeric region);GO:0000776(kinetochore);GO:0000777(condensed chromosome kinetochore);GO:0031145(anaphase-promoting complex-dependent catabolic process);GO:0043161(proteasome-mediated ubiquitin-dependent protein catabolic process);GO:0051437(positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition);GO:0051233(spindle midzone);GO:0007094(mitotic spindle assembly checkpoint);GO:0007062(sister chromatid cohesion);GO:0051436(negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle);GO:0008283(cell proliferation);GO:0042787(protein ubiquitination involved in ubiquitin-dependent protein catabolic process);GO:0000278(mitotic cell cycle);GO:0034501(protein localization to kinetochore);GO:0007093(mitotic cell cycle checkpoint);GO:0051754(meiotic sister chromatid cohesion, centromeric);GO:0007091(metaphase/anaphase transition of mitotic cell cycle);GO:0071459(protein localization to chromosome, centromeric region);GO:0000778(condensed nuclear chromosome kinetochore);GO:0000940(condensed chromosome outer kinetochore);GO:0005680(anaphase-promoting complex);GO:0005680(anaphase-promoting complex)","04110(Cell cycle);05166(HTLV-I infection);05166(HTLV-I infection)","K06637","EC:2.7.11.1","BUB1 mitotic checkpoint serine/threonine kinase B [Source:HGNC Symbol;Acc:HGNC:1149]",{"v":0.332869839142091,"d":"0.33"},{"v":0.111303308981233,"d":"0.11"},{"v":2.99065537394056,"d":"2.99"},{"v":1.58046167209133,"d":"1.58"},1,1,"up","no"]
["ENSG00000188992","LIPI","ENST00000344577","GO:0016020(membrane);GO:0016787(hydrolase activity);GO:0006629(lipid metabolic process);GO:0016042(lipid catabolic process);GO:0005576(extracellular region);GO:0052689(carboxylic ester hydrolase activity);GO:0005886(plasma membrane);GO:0008201(heparin binding);GO:0006654(phosphatidic acid biosynthetic process);GO:0004620(phospholipase activity)","NA","NA","NA","lipase I [Source:HGNC Symbol;Acc:HGNC:18821]",{"v":0.0270173990825688,"d":"0.03"},{"v":0.0224980802752294,"d":"0.02"},{"v":1.20087575259989,"d":"1.20"},{"v":0.264086891775701,"d":"0.26"},1,1,"up","no"]
["ENSG00000180660","MAB21L1","ENST00000379919","GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0016740(transferase activity);GO:0005525(GTP binding);GO:0005515(protein binding);GO:0007275(multicellular organism development);GO:0016779(nucleotidyltransferase activity);GO:0008284(positive regulation of cell proliferation);GO:0043010(camera-type eye development);GO:0009653(anatomical structure morphogenesis)","NA","NA","NA","mab-21 like 1 [Source:HGNC Symbol;Acc:HGNC:6757]",{"v":0.016976,"d":"0.02"},{"v":0.015067,"d":"0.02"},{"v":1.12670073670936,"d":"1.13"},{"v":0.172104371767201,"d":"0.17"},1,1,"up","no"]
["ENSG00000008196","TFAP2B","ENST00000393655","GO:0005634(nucleus);GO:0006355(regulation of transcription, DNA-templated);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0042803(protein homodimerization activity);GO:0003713(transcription coactivator activity);GO:0045893(positive regulation of transcription, DNA-templated);GO:0005515(protein binding);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0003714(transcription corepressor activity);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0005654(nucleoplasm);GO:0045444(fat cell differentiation);GO:0008285(negative regulation of cell proliferation);GO:0010842(retina layer formation);GO:0006006(glucose metabolic process);GO:0008284(positive regulation of cell proliferation);GO:0043565(sequence-specific DNA binding);GO:0043066(negative regulation of apoptotic process);GO:0045892(negative regulation of transcription, DNA-templated);GO:0046982(protein heterodimerization activity);GO:0050796(regulation of insulin secretion);GO:0000981(RNA polymerase II transcription factor activity, sequence-specific DNA binding);GO:0043154(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process);GO:0001105(RNA polymerase II transcription coactivator activity);GO:0042593(glucose homeostasis);GO:0003091(renal water homeostasis);GO:0035909(aorta morphogenesis);GO:0045595(regulation of cell differentiation);GO:0043525(positive regulation of neuron apoptotic process);GO:0043027(cysteine-type endopeptidase inhibitor activity involved in apoptotic process);GO:0046983(protein dimerization activity);GO:0001822(kidney development);GO:0000979(RNA polymerase II core promoter sequence-specific DNA binding);GO:0055074(calcium ion homeostasis);GO:0001106(RNA polymerase II transcription corepressor activity);GO:0001158(enhancer sequence-specific DNA binding);GO:0006915(apoptotic process);GO:0048485(sympathetic nervous system development);GO:0000983(transcription factor activity, RNA polymerase II core promoter sequence-specific);GO:0097070(ductus arteriosus closure);GO:0035810(positive regulation of urine volume);GO:0055062(phosphate ion homeostasis);GO:0030510(regulation of BMP signaling pathway);GO:0055078(sodium ion homeostasis);GO:0010960(magnesium ion homeostasis);GO:0001077(transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0003682(chromatin binding);GO:0006366(transcription from RNA polymerase II promoter);GO:0007423(sensory organ development);GO:0010226(response to lithium ion);GO:0035136(forelimb morphogenesis);GO:0035137(hindlimb morphogenesis);GO:0042493(response to drug);GO:0043524(negative regulation of neuron apoptotic process);GO:0043588(skin development);GO:0055075(potassium ion homeostasis);GO:0072017(distal tubule development);GO:0072044(collecting duct development);GO:0072210(metanephric nephron development);GO:0097275(cellular ammonia homeostasis);GO:0097276(cellular creatinine homeostasis);GO:0097277(cellular urea homeostasis)","NA","NA","NA","transcription factor AP-2 beta [Source:HGNC Symbol;Acc:HGNC:11743]",0,{"v":0.00746199447064563,"d":"0.01"},"-inf","-inf",1,1,"down","no"]
["ENSG00000236527","ARF4P2","ENST00000430209","NA","NA","NA","NA","ADP ribosylation factor 4 pseudogene 2 [Source:HGNC Symbol;Acc:HGNC:16599]",{"v":0.093494,"d":"0.09"},0,"inf","inf",1,1,"up","no"]
["MSTRG.8182","AC011462.2","ENST00000598887","NA","NA","NA","NA",null,{"v":0.145997,"d":"0.15"},0,"inf","inf",1,1,"up","no"]
["ENSG00000188585","CLEC20A","ENST00000623247","NA","NA","NA","NA","C-type lectin domain containing 20A [Source:HGNC Symbol;Acc:HGNC:34521]",0,0,1,0,1,1,"no","no"]
["ENSG00000166959","MS4A8","ENST00000300226;ENST00000533691","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016021(integral component of membrane)","NA","NA","NA","membrane spanning 4-domains A8 [Source:HGNC Symbol;Acc:HGNC:13380]",{"v":0.0144414285714286,"d":"0.01"},{"v":0.0176631707317073,"d":"0.02"},{"v":0.817601142557303,"d":"0.82"},{"v":-0.2905308825152,"d":"-0.29"},1,1,"down","no"]
["ENSG00000283567","AC008735.6","ENST00000635964","NA","NA","NA","NA",null,0,{"v":0.001648,"d":"0.00"},"-inf","-inf",1,1,"down","no"]
["MSTRG.987","AL513523.3","ENST00000434575","NA","NA","NA","NA",null,0,{"v":0.0679418735177866,"d":"0.07"},"-inf","-inf",1,1,"down","no"]
["ENSG00000258702","AL137786.1","ENST00000553378","NA","NA","NA","NA",null,0,{"v":0.007529,"d":"0.01"},"-inf","-inf",1,1,"down","no"]
["ENSG00000134760","DSG1","ENST00000257192","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0046872(metal ion binding);GO:0005509(calcium ion binding);GO:0007155(cell adhesion);GO:0007156(homophilic cell adhesion via plasma membrane adhesion molecules);GO:0005886(plasma membrane);GO:0030054(cell junction);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0031424(keratinization);GO:0031012(extracellular matrix);GO:0043312(neutrophil degranulation);GO:0005515(protein binding);GO:0009898(cytoplasmic side of plasma membrane);GO:0007043(cell-cell junction assembly);GO:0050821(protein stabilization);GO:0005911(cell-cell junction);GO:0016337(single organismal cell-cell adhesion);GO:0101003(ficolin-1-rich granule membrane);GO:0070268(cornification);GO:0001533(cornified envelope);GO:0030057(desmosome);GO:0015643(toxic substance binding);GO:0045295(gamma-catenin binding);GO:0016339(calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules);GO:0032570(response to progesterone);GO:0060135(maternal process involved in female pregnancy);GO:0016324(apical plasma membrane);GO:0016328(lateral plasma membrane)","05150(Staphylococcus aureus infection)","K07596","NA","desmoglein 1 [Source:HGNC Symbol;Acc:HGNC:3048]",{"v":0.0251202960776847,"d":"0.03"},{"v":1.50523895658797E-3,"d":"0.00"},{"v":16.6885768985322,"d":"16.69"},{"v":4.06078903047668,"d":"4.06"},1,1,"up","no"]
["MSTRG.8765","AC008074.3","ENST00000561559","NA","NA","NA","NA",null,{"v":0.754454,"d":"0.75"},{"v":0.329519,"d":"0.33"},{"v":2.28956145169171,"d":"2.29"},{"v":1.19507128737927,"d":"1.20"},1,1,"up","no"]
["MSTRG.12570","ZNF346-IT1","ENST00000515264","NA","NA","NA","NA","ZNF346 intronic transcript 1 [Source:HGNC Symbol;Acc:HGNC:41423]",{"v":0.041398,"d":"0.04"},{"v":0.275029,"d":"0.28"},{"v":0.150522308556552,"d":"0.15"},{"v":-2.73195077362465,"d":"-2.73"},1,1,"down","no"]
["MSTRG.1143","ADAMTS4","ENST00000478394;ENST00000367996","GO:0005615(extracellular space);GO:0016607(nuclear speck);GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0016787(hydrolase activity);GO:0008233(peptidase activity);GO:0006508(proteolysis);GO:0005576(extracellular region);GO:0005578(proteinaceous extracellular matrix);GO:0004222(metalloendopeptidase activity);GO:0008237(metallopeptidase activity);GO:0005515(protein binding);GO:0031012(extracellular matrix);GO:0001501(skeletal system development);GO:0022617(extracellular matrix disassembly);GO:0002020(protease binding);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016021(integral component of membrane)","NA","NA","NA","ADAM metallopeptidase with thrombospondin type 1 motif 4 [Source:HGNC Symbol;Acc:HGNC:220]",{"v":0.0690559763886201,"d":"0.07"},{"v":0.0233824737758854,"d":"0.02"},{"v":2.95332209288473,"d":"2.95"},{"v":1.56233870712111,"d":"1.56"},1,1,"up","no"]
["ENSG00000172461","FUT9","ENST00000302103","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016740(transferase activity);GO:0016757(transferase activity, transferring glycosyl groups);GO:0006486(protein glycosylation);GO:0005794(Golgi apparatus);GO:0032580(Golgi cisterna membrane);GO:0036065(fucosylation);GO:0008417(fucosyltransferase activity);GO:0005975(carbohydrate metabolic process);GO:0000139(Golgi membrane);GO:0042355(L-fucose catabolic process);GO:0046920(alpha-(1->3)-fucosyltransferase activity);GO:0007399(nervous system development)","00515(Mannose type O-glycan biosyntheis);00601(Glycosphingolipid biosynthesis - lacto and neolacto series);00603(Glycosphingolipid biosynthesis - globo and isoglobo series)","K03663","EC:2.4.1.152","fucosyltransferase 9 [Source:HGNC Symbol;Acc:HGNC:4020]",0,{"v":3.01521889350536E-3,"d":"0.00"},"-inf","-inf",1,1,"down","no"]
["MSTRG.8031","BNIP3P15","ENST00000604600","NA","NA","NA","NA","BCL2 interacting protein 3 pseudogene 15 [Source:HGNC Symbol;Acc:HGNC:49695]",0,{"v":0.151574,"d":"0.15"},"-inf","-inf",1,1,"down","no"]
["ENSG00000169488","OR4K15","ENST00000641512;ENST00000305051","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0004930(G-protein coupled receptor activity);GO:0007186(G-protein coupled receptor signaling pathway);GO:0005886(plasma membrane);GO:0004871(signal transducer activity);GO:0007165(signal transduction);GO:0004984(olfactory receptor activity);GO:0007608(sensory perception of smell);GO:0050896(response to stimulus);GO:0050911(detection of chemical stimulus involved in sensory perception of smell);GO:0004888(transmembrane signaling receptor activity);GO:0050907(detection of chemical stimulus involved in sensory perception);GO:0050907(detection of chemical stimulus involved in sensory perception)","04740(Olfactory transduction);04740(Olfactory transduction)","K04257","NA","olfactory receptor family 4 subfamily K member 15 [Source:HGNC Symbol;Acc:HGNC:15353]",{"v":0.042272,"d":"0.04"},0,"inf","inf",1,1,"up","no"]
["MSTRG.13539","JAZF1-AS1","ENST00000455963;ENST00000444500;ENST00000436758","NA","NA","NA","NA","JAZF1 antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:41218]",{"v":0.0666483499511241,"d":"0.07"},{"v":0.0202397250733138,"d":"0.02"},{"v":3.29294739477466,"d":"3.29"},{"v":1.7193794648929,"d":"1.72"},1,1,"up","no"]
["MSTRG.1821","AC022540.1","ENST00000448214;ENST00000609392","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000250992","AC139491.3","ENST00000509643","NA","NA","NA","NA",null,{"v":0.073646,"d":"0.07"},0,"inf","inf",1,1,"up","no"]
["ENSG00000260144","AC100827.2","ENST00000563214","NA","NA","NA","NA",null,0,{"v":0.016247,"d":"0.02"},"-inf","-inf",1,1,"down","no"]
["ENSG00000249159","AC091965.1","ENST00000607662","NA","NA","NA","NA",null,{"v":2.21863021582734E-3,"d":"0.00"},0,"inf","inf",1,1,"up","no"]
["ENSG00000159650","UROC1","ENST00000290868","GO:0016829(lyase activity);GO:0005829(cytosol);GO:0006548(histidine catabolic process);GO:0006547(histidine metabolic process);GO:0019556(histidine catabolic process to glutamate and formamide);GO:0019557(histidine catabolic process to glutamate and formate);GO:0016153(urocanate hydratase activity)","00340(Histidine metabolism)","K01712","EC:4.2.1.49","urocanate hydratase 1 [Source:HGNC Symbol;Acc:HGNC:26444]",{"v":0.0443309957945329,"d":"0.04"},{"v":0.0286512649444278,"d":"0.03"},{"v":1.54726138201987,"d":"1.55"},{"v":0.62971693478978,"d":"0.63"},1,1,"up","no"]
["MSTRG.1017","UBE2Q1-AS1","ENST00000441613","NA","NA","NA","NA","UBE2Q1 antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:40722]",{"v":0.061274,"d":"0.06"},{"v":0.027277,"d":"0.03"},{"v":2.24636140338014,"d":"2.25"},{"v":1.16759005281421,"d":"1.17"},1,1,"up","no"]
["ENSG00000284715","AP001153.1","ENST00000641024","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["MSTRG.11611","LNX1","ENST00000263925;ENST00000306888","GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0016740(transferase activity);GO:0016567(protein ubiquitination);GO:0005515(protein binding);GO:0004842(ubiquitin-protein transferase activity);GO:0030165(PDZ domain binding);GO:0006511(ubiquitin-dependent protein catabolic process);GO:0042787(protein ubiquitination involved in ubiquitin-dependent protein catabolic process);GO:0051260(protein homooligomerization);GO:0051260(protein homooligomerization)","NA","NA","NA","ligand of numb-protein X 1 [Source:HGNC Symbol;Acc:HGNC:6657]",{"v":0.0407979965065502,"d":"0.04"},{"v":0.0675462693449782,"d":"0.07"},{"v":0.604000737600816,"d":"0.60"},{"v":-0.727377783528417,"d":"-0.73"},1,1,"down","no"]
["MSTRG.2236","C11orf16","ENST00000528998;ENST00000326053","NA","NA","NA","NA","chromosome 11 open reading frame 16 [Source:HGNC Symbol;Acc:HGNC:1169]",{"v":0.0232538619102417,"d":"0.02"},{"v":0.0345342876869965,"d":"0.03"},{"v":0.673355770966073,"d":"0.67"},{"v":-0.570559133305253,"d":"-0.57"},1,1,"down","no"]
["ENSG00000180068","OR3A4P","ENST00000624752;ENST00000323164","NA","NA","NA","NA","olfactory receptor family 3 subfamily A member 4 pseudogene [Source:HGNC Symbol;Acc:HGNC:15510]",{"v":0.0263734607491021,"d":"0.03"},{"v":0.0608632550025654,"d":"0.06"},{"v":0.433323205405141,"d":"0.43"},{"v":-1.20648459673481,"d":"-1.21"},1,1,"down","no"]
["ENSG00000135298","ADGRB3","ENST00000370598","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0004930(G-protein coupled receptor activity);GO:0007186(G-protein coupled receptor signaling pathway);GO:0005886(plasma membrane);GO:0043547(positive regulation of GTPase activity);GO:0005515(protein binding);GO:0004871(signal transducer activity);GO:0007165(signal transduction);GO:0004888(transmembrane signaling receptor activity);GO:0007166(cell surface receptor signaling pathway);GO:0005096(GTPase activator activity);GO:0016525(negative regulation of angiogenesis);GO:0007520(myoblast fusion);GO:0016322(neuron remodeling);GO:0048814(regulation of dendrite morphogenesis);GO:0051965(positive regulation of synapse assembly);GO:0061743(motor learning);GO:0099558(maintenance of synapse structure);GO:0043083(synaptic cleft);GO:0098794(postsynapse)","NA","NA","NA","adhesion G protein-coupled receptor B3 [Source:HGNC Symbol;Acc:HGNC:945]",{"v":0.0140739568567026,"d":"0.01"},{"v":0.0260513590138675,"d":"0.03"},{"v":0.540238873880278,"d":"0.54"},{"v":-0.888330639534253,"d":"-0.89"},1,1,"down","no"]
["ENSG00000171502","COL24A1","ENST00000370571;ENST00000485434","GO:0005515(protein binding);GO:0005576(extracellular region);GO:0005581(collagen trimer);GO:0005578(proteinaceous extracellular matrix);GO:0005201(extracellular matrix structural constituent);GO:0005788(endoplasmic reticulum lumen);GO:0002244(hematopoietic progenitor cell differentiation);GO:0002244(hematopoietic progenitor cell differentiation)","04974(Protein digestion and absorption);04974(Protein digestion and absorption)","K19721","NA","collagen type XXIV alpha 1 chain [Source:HGNC Symbol;Acc:HGNC:20821]",{"v":0.0476344769021739,"d":"0.05"},{"v":0.037164122909699,"d":"0.04"},{"v":1.2817328426643,"d":"1.28"},{"v":0.358095585881258,"d":"0.36"},1,1,"up","no"]
["ENSG00000175485","OR52W1","ENST00000311352","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0007186(G-protein coupled receptor signaling pathway);GO:0005886(plasma membrane);GO:0004871(signal transducer activity);GO:0007165(signal transduction);GO:0004930(G-protein coupled receptor activity);GO:0004984(olfactory receptor activity);GO:0007608(sensory perception of smell);GO:0050896(response to stimulus);GO:0050911(detection of chemical stimulus involved in sensory perception of smell)","04740(Olfactory transduction)","K04257","NA","olfactory receptor family 52 subfamily W member 1 [Source:HGNC Symbol;Acc:HGNC:15239]",0,{"v":0.16382,"d":"0.16"},"-inf","-inf",1,1,"down","no"]
["ENSG00000234572","LINC01800","ENST00000445865","NA","NA","NA","NA","long intergenic non-protein coding RNA 1800 [Source:HGNC Symbol;Acc:HGNC:52590]",{"v":0.025827,"d":"0.03"},{"v":0.128072,"d":"0.13"},{"v":0.201660003747892,"d":"0.20"},{"v":-2.31000311959488,"d":"-2.31"},1,1,"down","no"]
["ENSG00000197161","AC023080.1","ENST00000551663","NA","NA","NA","NA",null,0,{"v":0.049005,"d":"0.05"},"-inf","-inf",1,1,"down","no"]
["ENSG00000215274","GAGE10","ENST00000407599","NA","NA","NA","NA","G antigen 10 [Source:HGNC Symbol;Acc:HGNC:30968]",{"v":0.135224,"d":"0.14"},{"v":0.014014,"d":"0.01"},{"v":9.64920793492222,"d":"9.65"},{"v":3.27041052214666,"d":"3.27"},1,1,"up","no"]
["ENSG00000067601","PMS2P4","ENST00000414507;ENST00000412466","NA","NA","NA","NA","PMS1 homolog 2, mismatch repair system component pseudogene 4 [Source:HGNC Symbol;Acc:HGNC:9129]",{"v":0.145477705660377,"d":"0.15"},{"v":0.20671899245283,"d":"0.21"},{"v":0.703746201228088,"d":"0.70"},{"v":-0.506872865238637,"d":"-0.51"},1,1,"down","no"]
["MSTRG.2174","OLFM5P","ENST00000411807","NA","NA","NA","NA","olfactomedin family member 5, pseudogene [Source:HGNC Symbol;Acc:HGNC:51927]",{"v":0.009564,"d":"0.01"},{"v":0.147861,"d":"0.15"},{"v":0.0646823706048248,"d":"0.06"},{"v":-3.95048363531146,"d":"-3.95"},1,1,"down","no"]
["MSTRG.8576","KRTCAP3","ENST00000464699;ENST00000288873;ENST00000494572;ENST00000543753","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016021(integral component of membrane)","NA","NA","NA","keratinocyte associated protein 3 [Source:HGNC Symbol;Acc:HGNC:28943]",{"v":0.193529169636493,"d":"0.19"},{"v":0.0389220784034212,"d":"0.04"},{"v":4.97222084675422,"d":"4.97"},{"v":2.31389037672853,"d":"2.31"},1,1,"up","no"]
["ENSG00000101638","ST8SIA5","ENST00000589088;ENST00000538168;ENST00000590497","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016740(transferase activity);GO:0008373(sialyltransferase activity);GO:0016757(transferase activity, transferring glycosyl groups);GO:0006486(protein glycosylation);GO:0097503(sialylation);GO:0005794(Golgi apparatus);GO:0005515(protein binding);GO:0000139(Golgi membrane);GO:0005975(carbohydrate metabolic process);GO:0003828(alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity);GO:0006688(glycosphingolipid biosynthetic process);GO:0006688(glycosphingolipid biosynthetic process)","00604(Glycosphingolipid biosynthesis - ganglio series);00604(Glycosphingolipid biosynthesis - ganglio series)","K03369","EC:2.4.99.-","ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5 [Source:HGNC Symbol;Acc:HGNC:17827]",{"v":0.00243135531065932,"d":"0.00"},{"v":0.00567285445563367,"d":"0.01"},{"v":0.428594692438259,"d":"0.43"},{"v":-1.22231411057616,"d":"-1.22"},1,1,"down","no"]
["MSTRG.5922","AC007728.1","ENST00000564510","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000183747","ACSM2A","ENST00000573854;ENST00000574692","GO:0003824(catalytic activity);GO:0008152(metabolic process);GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0006629(lipid metabolic process);GO:0006631(fatty acid metabolic process);GO:0005739(mitochondrion);GO:0016874(ligase activity);GO:0005759(mitochondrial matrix);GO:0042593(glucose homeostasis);GO:0070328(triglyceride homeostasis);GO:0003996(acyl-CoA ligase activity);GO:0004321(fatty-acyl-CoA synthase activity);GO:0015645(fatty acid ligase activity);GO:0047760(butyrate-CoA ligase activity);GO:0006633(fatty acid biosynthetic process);GO:0036112(medium-chain fatty-acyl-CoA metabolic process);GO:0036112(medium-chain fatty-acyl-CoA metabolic process)","00650(Butanoate metabolism);00650(Butanoate metabolism)","K01896","EC:6.2.1.2","acyl-CoA synthetase medium chain family member 2A [Source:HGNC Symbol;Acc:HGNC:32017]",{"v":0.0138061792994019,"d":"0.01"},{"v":0.0177369294519712,"d":"0.02"},{"v":0.778386097592983,"d":"0.78"},{"v":-0.361442151871079,"d":"-0.36"},1,1,"down","no"]
["ENSG00000230665","THAP12P1","ENST00000398672","NA","NA","NA","NA","THAP domain containing 12 pseudogene 1 [Source:HGNC Symbol;Acc:HGNC:39563]",{"v":0.023333,"d":"0.02"},0,"inf","inf",1,1,"up","no"]
["ENSG00000231701","BMS1P13","ENST00000417301","NA","NA","NA","NA","BMS1, ribosome biogenesis factor pseudogene 13 [Source:HGNC Symbol;Acc:HGNC:49158]",{"v":0.010631,"d":"0.01"},{"v":0.017184,"d":"0.02"},{"v":0.618656890130354,"d":"0.62"},{"v":-0.692788588755511,"d":"-0.69"},1,1,"down","no"]
["ENSG00000237429","BX293535.1","ENST00000443579","NA","NA","NA","NA",null,{"v":0.076844,"d":"0.08"},{"v":0.449253,"d":"0.45"},{"v":0.171048384763151,"d":"0.17"},{"v":-2.54752361431382,"d":"-2.55"},1,1,"down","no"]
["MSTRG.8306","AC011450.1","ENST00000602554;ENST00000358234","NA","NA","NA","NA",null,{"v":0.327635809756098,"d":"0.33"},{"v":0.46999696097561,"d":"0.47"},{"v":0.697101975034048,"d":"0.70"},{"v":-0.520558379805423,"d":"-0.52"},1,1,"down","no"]
["MSTRG.10149","MIR6816","ENST00000620368","NA","NA","NA","NA","microRNA 6816 [Source:HGNC Symbol;Acc:HGNC:50256]",{"v":0.34268,"d":"0.34"},0,"inf","inf",1,1,"up","no"]
["ENSG00000282418","AC092811.2","ENST00000632561","NA","NA","NA","NA",null,0,{"v":0.0672,"d":"0.07"},"-inf","-inf",1,1,"down","no"]
["ENSG00000167646","DNAAF3","ENST00000528476","GO:0005737(cytoplasm);GO:0030030(cell projection organization);GO:0044458(motile cilium assembly);GO:0070286(axonemal dynein complex assembly)","NA","NA","NA","dynein axonemal assembly factor 3 [Source:HGNC Symbol;Acc:HGNC:30492]",0,{"v":0.012052056632344,"d":"0.01"},"-inf","-inf",1,1,"down","no"]
["ENSG00000179253","AL162457.1","ENST00000317652","NA","NA","NA","NA",null,{"v":0.097323,"d":"0.10"},{"v":0.097787,"d":"0.10"},{"v":0.995254992994979,"d":"1.00"},{"v":-0.00686189084049243,"d":"-0.01"},1,1,"down","no"]
["ENSG00000224960","PPP4R3CP","ENST00000412172","NA","NA","NA","NA","protein phosphatase 4 regulatory subunit 3C, pseudogene [Source:HGNC Symbol;Acc:HGNC:33146]",0,{"v":0.029143,"d":"0.03"},"-inf","-inf",1,1,"down","no"]
["ENSG00000155011","DKK2","ENST00000285311;ENST00000510534","GO:0005615(extracellular space);GO:0090090(negative regulation of canonical Wnt signaling pathway);GO:0090263(positive regulation of canonical Wnt signaling pathway);GO:0005576(extracellular region);GO:0007275(multicellular organism development);GO:0016055(Wnt signaling pathway);GO:0030178(negative regulation of Wnt signaling pathway);GO:0039706(co-receptor binding);GO:0039706(co-receptor binding)","04310(Wnt signaling pathway);04310(Wnt signaling pathway)","K02165","NA","dickkopf WNT signaling pathway inhibitor 2 [Source:HGNC Symbol;Acc:HGNC:2892]",{"v":0.023802408890947,"d":"0.02"},{"v":0.0211271859226673,"d":"0.02"},{"v":1.12662467107886,"d":"1.13"},{"v":0.172006969494478,"d":"0.17"},1,1,"up","no"]
["ENSG00000254664","AC103681.2","ENST00000527450","NA","NA","NA","NA",null,{"v":0.36102,"d":"0.36"},0,"inf","inf",1,1,"up","no"]
["ENSG00000236761","CTAGE9","ENST00000314099","GO:0016020(membrane);GO:0016021(integral component of membrane)","NA","NA","NA","CTAGE family member 9 [Source:HGNC Symbol;Acc:HGNC:37275]",{"v":0.112201,"d":"0.11"},{"v":0.066288,"d":"0.07"},{"v":1.69262913347816,"d":"1.69"},{"v":0.759265903591581,"d":"0.76"},1,1,"up","no"]
["ENSG00000196739","COL27A1","ENST00000356083","GO:0046872(metal ion binding);GO:0005576(extracellular region);GO:0005581(collagen trimer);GO:0005578(proteinaceous extracellular matrix);GO:0005201(extracellular matrix structural constituent);GO:0005788(endoplasmic reticulum lumen);GO:0003431(growth plate cartilage chondrocyte development);GO:0030198(extracellular matrix organization);GO:0005583(fibrillar collagen trimer)","04974(Protein digestion and absorption)","K19721","NA","collagen type XXVII alpha 1 chain [Source:HGNC Symbol;Acc:HGNC:22986]",{"v":0.0224071096654275,"d":"0.02"},{"v":0.0237124971404061,"d":"0.02"},{"v":0.944949388196057,"d":"0.94"},{"v":-0.0816910347112625,"d":"-0.08"},1,1,"down","no"]
["ENSG00000179954","SSC5D","ENST00000389623;ENST00000587166","GO:0016020(membrane);GO:0005044(scavenger receptor activity);GO:0006898(receptor-mediated endocytosis);GO:0005737(cytoplasm);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0043236(laminin binding);GO:0007275(multicellular organism development);GO:0005615(extracellular space);GO:0002376(immune system process);GO:0045087(innate immune response);GO:0001968(fibronectin binding);GO:0050840(extracellular matrix binding);GO:0042494(detection of bacterial lipoprotein);GO:2000483(negative regulation of interleukin-8 secretion);GO:0005622(intracellular);GO:0031012(extracellular matrix);GO:0006952(defense response);GO:0050829(defense response to Gram-negative bacterium);GO:0050830(defense response to Gram-positive bacterium);GO:2000482(regulation of interleukin-8 secretion);GO:2000482(regulation of interleukin-8 secretion)","NA","NA","NA","scavenger receptor cysteine rich family member with 5 domains [Source:HGNC Symbol;Acc:HGNC:26641]",{"v":0.0745372478807766,"d":"0.07"},{"v":0.0287354737489746,"d":"0.03"},{"v":2.59391052786928,"d":"2.59"},{"v":1.37512871735929,"d":"1.38"},1,1,"up","no"]
["ENSG00000261247","GOLGA8T","ENST00000565649;ENST00000569052","GO:0005794(Golgi apparatus);GO:0005794(Golgi apparatus)","NA","NA","NA","golgin A8 family member T [Source:HGNC Symbol;Acc:HGNC:44410]",{"v":0.21832596314258,"d":"0.22"},{"v":0.162752326382153,"d":"0.16"},{"v":1.34146139717804,"d":"1.34"},{"v":0.42380553920439,"d":"0.42"},1,1,"up","no"]
["ENSG00000223535","FAM90A17P","ENST00000533716","NA","NA","NA","NA","family with sequence similarity 90 member A17, pseudogene [Source:HGNC Symbol;Acc:HGNC:32265]",0,{"v":0.018922,"d":"0.02"},"-inf","-inf",1,1,"down","no"]
["ENSG00000259848","AC097374.1","ENST00000568768;ENST00000582835","NA","NA","NA","NA",null,{"v":0.0223949865470852,"d":"0.02"},{"v":0.00474765036434978,"d":"0.00"},{"v":4.71706735509626,"d":"4.72"},{"v":2.23789020128506,"d":"2.24"},1,1,"up","no"]
["ENSG00000266265","KLF14","ENST00000583337","GO:0003676(nucleic acid binding);GO:0003682(chromatin binding);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:1902070(positive regulation of sphingolipid mediated signaling pathway)","NA","NA","NA","Kruppel like factor 14 [Source:HGNC Symbol;Acc:HGNC:23025]",{"v":0.034304,"d":"0.03"},0,"inf","inf",1,1,"up","no"]
["ENSG00000249579","AC113420.1","ENST00000507903","NA","NA","NA","NA",null,0,{"v":0.079902,"d":"0.08"},"-inf","-inf",1,1,"down","no"]
["ENSG00000134489","HRH4","ENST00000256906","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0004930(G-protein coupled receptor activity);GO:0007186(G-protein coupled receptor signaling pathway);GO:0005886(plasma membrane);GO:0004871(signal transducer activity);GO:0007165(signal transduction);GO:0006954(inflammatory response);GO:0004969(histamine receptor activity);GO:0008150(biological_process);GO:0043408(regulation of MAPK cascade);GO:0007204(positive regulation of cytosolic calcium ion concentration);GO:0007194(negative regulation of adenylate cyclase activity)","04080(Neuroactive ligand-receptor interaction)","K04152","NA","histamine receptor H4 [Source:HGNC Symbol;Acc:HGNC:17383]",{"v":0.21529,"d":"0.22"},{"v":0.129981,"d":"0.13"},{"v":1.6563190004693,"d":"1.66"},{"v":0.727980556939861,"d":"0.73"},1,1,"up","no"]
["ENSG00000271763","AC091544.6","ENST00000607766","NA","NA","NA","NA",null,{"v":0.096165,"d":"0.10"},0,"inf","inf",1,1,"up","no"]
["ENSG00000165973","NELL1","ENST00000298925","GO:0005509(calcium ion binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0048471(perinuclear region of cytoplasm);GO:0030154(cell differentiation);GO:0007399(nervous system development);GO:0030501(positive regulation of bone mineralization);GO:0005635(nuclear envelope);GO:0010468(regulation of gene expression);GO:0045669(positive regulation of osteoblast differentiation);GO:0033689(negative regulation of osteoblast proliferation);GO:1903363(negative regulation of cellular protein catabolic process)","NA","NA","NA","neural EGFL like 1 [Source:HGNC Symbol;Acc:HGNC:7750]",{"v":0.0256105381427764,"d":"0.03"},{"v":0.0280246745149746,"d":"0.03"},{"v":0.913856756091556,"d":"0.91"},{"v":-0.12996004937635,"d":"-0.13"},1,1,"down","no"]
["ENSG00000152034","MCHR2","ENST00000281806","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0004930(G-protein coupled receptor activity);GO:0007186(G-protein coupled receptor signaling pathway);GO:0005886(plasma membrane);GO:0004871(signal transducer activity);GO:0007165(signal transduction);GO:0005887(integral component of plasma membrane);GO:0007200(phospholipase C-activating G-protein coupled receptor signaling pathway);GO:0007218(neuropeptide signaling pathway);GO:0008528(G-protein coupled peptide receptor activity)","04080(Neuroactive ligand-receptor interaction)","K05054","NA","melanin concentrating hormone receptor 2 [Source:HGNC Symbol;Acc:HGNC:20867]",0,{"v":0.000763264214046823,"d":"0.00"},"-inf","-inf",1,1,"down","no"]
["ENSG00000266916","ZNF793-AS1","ENST00000585890;ENST00000587060;ENST00000588845","NA","NA","NA","NA","ZNF793 antisense RNA 1 (head to head) [Source:HGNC Symbol;Acc:HGNC:51303]",{"v":0.0638149992429977,"d":"0.06"},{"v":0.112822034065102,"d":"0.11"},{"v":0.565625321080228,"d":"0.57"},{"v":-0.822081388850397,"d":"-0.82"},1,1,"down","no"]
["ENSG00000279847","C8orf87","ENST00000521906","NA","NA","NA","NA","chromosome 8 open reading frame 87 [Source:HGNC Symbol;Acc:HGNC:42974]",0,{"v":0.0278978366718028,"d":"0.03"},"-inf","-inf",1,1,"down","no"]
["ENSG00000250247","SEPHS2P1","ENST00000511618","NA","NA","NA","NA","selenophosphate synthetase 2 pseudogene 1 [Source:HGNC Symbol;Acc:HGNC:42165]",0,{"v":0.039132,"d":"0.04"},"-inf","-inf",1,1,"down","no"]
["ENSG00000168032","ENTPD3","ENST00000301825","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0016787(hydrolase activity);GO:0005515(protein binding);GO:0005886(plasma membrane);GO:0017110(nucleoside-diphosphatase activity);GO:0034656(nucleobase-containing small molecule catabolic process);GO:0017111(nucleoside-triphosphatase activity);GO:0102490(8-oxo-dGTP phosphohydrolase activity);GO:0009134(nucleoside diphosphate catabolic process);GO:0009143(nucleoside triphosphate catabolic process)","00230(Purine metabolism);00240(Pyrimidine metabolism);05169(Epstein-Barr virus infection)","K01510","EC:3.6.1.5","ectonucleoside triphosphate diphosphohydrolase 3 [Source:HGNC Symbol;Acc:HGNC:3365]",{"v":0.0326023842496285,"d":"0.03"},{"v":0.0773168344725111,"d":"0.08"},{"v":0.421672517661336,"d":"0.42"},{"v":-1.24580509728198,"d":"-1.25"},1,1,"down","no"]
["ENSG00000270385","AC133539.2","ENST00000604757","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["MSTRG.2283","OR7E14P","ENST00000530490;ENST00000526721","NA","NA","NA","NA","olfactory receptor family 7 subfamily E member 14 pseudogene [Source:HGNC Symbol;Acc:HGNC:8385]",{"v":0.037269700729927,"d":"0.04"},{"v":0.0328583941605839,"d":"0.03"},{"v":1.13425204371779,"d":"1.13"},{"v":0.181741259167489,"d":"0.18"},1,1,"up","no"]
["MSTRG.2927","AP003392.3","ENST00000531886","NA","NA","NA","NA",null,{"v":0.006608,"d":"0.01"},0,"inf","inf",1,1,"up","no"]
["ENSG00000168158","OR2C1","ENST00000304936","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0004930(G-protein coupled receptor activity);GO:0007186(G-protein coupled receptor signaling pathway);GO:0005886(plasma membrane);GO:0004871(signal transducer activity);GO:0007165(signal transduction);GO:0004984(olfactory receptor activity);GO:0007608(sensory perception of smell);GO:0050896(response to stimulus);GO:0050911(detection of chemical stimulus involved in sensory perception of smell);GO:0005938(cell cortex)","04740(Olfactory transduction)","K04257","NA","olfactory receptor family 2 subfamily C member 1 [Source:HGNC Symbol;Acc:HGNC:8242]",{"v":0.036559,"d":"0.04"},{"v":0.064574,"d":"0.06"},{"v":0.566156657478242,"d":"0.57"},{"v":-0.820726787951464,"d":"-0.82"},1,1,"down","no"]
["ENSG00000198889","DCAF12L1","ENST00000371126","GO:0005515(protein binding);GO:0003674(molecular_function);GO:0008150(biological_process);GO:0005575(cellular_component)","NA","NA","NA","DDB1 and CUL4 associated factor 12 like 1 [Source:HGNC Symbol;Acc:HGNC:29395]",{"v":0.030397,"d":"0.03"},{"v":0.0134,"d":"0.01"},{"v":2.2684328358209,"d":"2.27"},{"v":1.18169594473931,"d":"1.18"},1,1,"up","no"]
["ENSG00000227045","AL589765.1","ENST00000457548","NA","NA","NA","NA",null,0,{"v":0.005516,"d":"0.01"},"-inf","-inf",1,1,"down","no"]
["ENSG00000243368","MCCC1-AS1","ENST00000471731","NA","NA","NA","NA","MCCC1 antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:40366]",{"v":0.151744,"d":"0.15"},0,"inf","inf",1,1,"up","no"]
["ENSG00000258927","AL133467.2","ENST00000555032","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000268940","CT45A1","ENST00000594117","NA","NA","NA","NA","cancer/testis antigen family 45 member A1 [Source:HGNC Symbol;Acc:HGNC:33267]",{"v":0.0237671524528302,"d":"0.02"},{"v":0.0174305577358491,"d":"0.02"},{"v":1.3635336753424,"d":"1.36"},{"v":0.44735033109259,"d":"0.45"},1,1,"up","no"]
["ENSG00000255364","SMILR","ENST00000533992","NA","NA","NA","NA","smooth muscle induced lncRNA, enhancer of proliferation [Source:HGNC Symbol;Acc:HGNC:51825]",0,{"v":0.555242,"d":"0.56"},"-inf","-inf",1,1,"down","no"]
["MSTRG.8110","AC022144.1","ENST00000602255","NA","NA","NA","NA",null,{"v":0.097599,"d":"0.10"},0,"inf","inf",1,1,"up","no"]
["ENSG00000229670","PKP4P1","ENST00000426801","NA","NA","NA","NA","plakophilin 4 pseudogene 1 [Source:HGNC Symbol;Acc:HGNC:42661]",{"v":0.023819,"d":"0.02"},{"v":0.021142,"d":"0.02"},{"v":1.12661999810803,"d":"1.13"},{"v":0.172000985526616,"d":"0.17"},1,1,"up","no"]
["ENSG00000165304","MELK","ENST00000298048","GO:0016020(membrane);GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0018108(peptidyl-tyrosine phosphorylation);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0007049(cell cycle);GO:0004715(non-membrane spanning protein tyrosine kinase activity);GO:0006915(apoptotic process);GO:0000226(microtubule cytoskeleton organization);GO:0030010(establishment of cell polarity);GO:0005509(calcium ion binding);GO:0005634(nucleus);GO:0008289(lipid binding);GO:0035556(intracellular signal transduction);GO:0005938(cell cortex);GO:0008283(cell proliferation);GO:0043065(positive regulation of apoptotic process);GO:0046777(protein autophosphorylation);GO:0030097(hemopoiesis);GO:0000086(G2/M transition of mitotic cell cycle);GO:0061351(neural precursor cell proliferation);GO:0008631(intrinsic apoptotic signaling pathway in response to oxidative stress);GO:0005737(cytoplasm)","NA","NA","NA","maternal embryonic leucine zipper kinase [Source:HGNC Symbol;Acc:HGNC:16870]",{"v":0.186305770975057,"d":"0.19"},{"v":0.0401013151927438,"d":"0.04"},{"v":4.64587682672234,"d":"4.65"},{"v":2.21595090536659,"d":"2.22"},1,1,"up","no"]
["ENSG00000258168","AC025569.1","ENST00000548924;ENST00000548687;ENST00000549460","NA","NA","NA","NA",null,{"v":0.0664319244660804,"d":"0.07"},{"v":0.00716461793341708,"d":"0.01"},{"v":9.27222150342865,"d":"9.27"},{"v":3.2129150311935,"d":"3.21"},1,1,"up","no"]
["MSTRG.7854","AC092069.1","ENST00000589120","NA","NA","NA","NA",null,{"v":0.002538,"d":"0.00"},0,"inf","inf",1,1,"up","no"]
["ENSG00000150510","FAM124A","ENST00000322475","GO:0005515(protein binding)","NA","NA","NA","family with sequence similarity 124 member A [Source:HGNC Symbol;Acc:HGNC:26413]",{"v":0.0220631360787824,"d":"0.02"},{"v":0.0589754489704566,"d":"0.06"},{"v":0.374107132102289,"d":"0.37"},{"v":-1.4184766247203,"d":"-1.42"},1,1,"down","no"]
["ENSG00000255261","OR7E4P","ENST00000530317","NA","NA","NA","NA","olfactory receptor family 7 subfamily E member 4 pseudogene [Source:HGNC Symbol;Acc:HGNC:8424]",0,{"v":0.045038,"d":"0.05"},"-inf","-inf",1,1,"down","no"]
["ENSG00000243289","AGAP13P","ENST00000417888","NA","NA","NA","NA","ArfGAP with GTPase domain, ankyrin repeat and PH domain 13, pseudogene [Source:HGNC Symbol;Acc:HGNC:23499]",{"v":0.292929,"d":"0.29"},{"v":0.19141,"d":"0.19"},{"v":1.53037458857949,"d":"1.53"},{"v":0.613884823468172,"d":"0.61"},1,1,"up","no"]
["ENSG00000124134","KCNS1","ENST00000306117","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0055085(transmembrane transport);GO:0005216(ion channel activity);GO:0006811(ion transport);GO:0005244(voltage-gated ion channel activity);GO:0005249(voltage-gated potassium channel activity);GO:0005267(potassium channel activity);GO:0006813(potassium ion transport);GO:0034765(regulation of ion transmembrane transport);GO:0051260(protein homooligomerization);GO:0071805(potassium ion transmembrane transport);GO:0008076(voltage-gated potassium channel complex);GO:0005886(plasma membrane);GO:0048471(perinuclear region of cytoplasm);GO:0005515(protein binding);GO:1902259(regulation of delayed rectifier potassium channel activity);GO:0015459(potassium channel regulator activity);GO:0005251(delayed rectifier potassium channel activity)","NA","NA","NA","potassium voltage-gated channel modifier subfamily S member 1 [Source:HGNC Symbol;Acc:HGNC:6300]",{"v":0.043911,"d":"0.04"},{"v":0.037735,"d":"0.04"},{"v":1.16366768252286,"d":"1.16"},{"v":0.218679115610973,"d":"0.22"},1,1,"up","no"]
["ENSG00000135409","AMHR2","ENST00000257863","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0005515(protein binding);GO:0007165(signal transduction);GO:0004702(signal transducer, downstream of receptor, with serine/threonine kinase activity);GO:0023014(signal transduction by protein phosphorylation);GO:0005886(plasma membrane);GO:0004675(transmembrane receptor protein serine/threonine kinase activity);GO:0007178(transmembrane receptor protein serine/threonine kinase signaling pathway);GO:0004872(receptor activity);GO:0007548(sex differentiation);GO:0030509(BMP signaling pathway);GO:0001880(Mullerian duct regression);GO:0042562(hormone binding);GO:0005026(transforming growth factor beta receptor activity, type II);GO:1990272(anti-Mullerian hormone receptor activity);GO:0007179(transforming growth factor beta receptor signaling pathway);GO:0008584(male gonad development);GO:0008585(female gonad development);GO:1902613(negative regulation of anti-Mullerian hormone signaling pathway);GO:1990262(anti-Mullerian hormone signaling pathway);GO:0005887(integral component of plasma membrane)","04350(TGF-beta signaling pathway);04060(Cytokine-cytokine receptor interaction)","K04672","EC:2.7.11.30","anti-Mullerian hormone receptor type 2 [Source:HGNC Symbol;Acc:HGNC:465]",{"v":0.0372118098351336,"d":"0.04"},{"v":0.0116413669698692,"d":"0.01"},{"v":3.1965154892417,"d":"3.20"},{"v":1.67650008467489,"d":"1.68"},1,1,"up","no"]
["MSTRG.8986","TMEM131","MSTRG.8986.1","NA","NA","NA","NA",null,0,{"v":0.242346,"d":"0.24"},"-inf","-inf",1,1,"down","no"]
["ENSG00000258334","AC125611.4","ENST00000553259","NA","NA","NA","NA",null,{"v":0.033782,"d":"0.03"},0,"inf","inf",1,1,"up","no"]
["MSTRG.2376","RN7SL652P","ENST00000577769","NA","NA","NA","NA","RNA, 7SL, cytoplasmic 652, pseudogene [Source:HGNC Symbol;Acc:HGNC:46668]",{"v":0.325546,"d":"0.33"},0,"inf","inf",1,1,"up","no"]
["ENSG00000132518","GUCY2D","ENST00000254854","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0035556(intracellular signal transduction);GO:0016829(lyase activity);GO:0005525(GTP binding);GO:0050896(response to stimulus);GO:0016849(phosphorus-oxygen lyase activity);GO:0009190(cyclic nucleotide biosynthetic process);GO:0005515(protein binding);GO:0004383(guanylate cyclase activity);GO:0006182(cGMP biosynthetic process);GO:0007601(visual perception);GO:0005887(integral component of plasma membrane);GO:0004872(receptor activity);GO:0022400(regulation of rhodopsin mediated signaling pathway);GO:0008074(guanylate cyclase complex, soluble);GO:0097381(photoreceptor disc membrane);GO:0007168(receptor guanylyl cyclase signaling pathway);GO:0005640(nuclear outer membrane)","00230(Purine metabolism);04744(Phototransduction);04740(Olfactory transduction)","K12321","EC:4.6.1.2","guanylate cyclase 2D, retinal [Source:HGNC Symbol;Acc:HGNC:4689]",{"v":0.0790960094059406,"d":"0.08"},{"v":0.00903996237623762,"d":"0.01"},{"v":8.74959497772378,"d":"8.75"},{"v":3.129216235556,"d":"3.13"},1,1,"up","no"]
["ENSG00000267682","AC016590.2","ENST00000592319","NA","NA","NA","NA",null,{"v":0.124698,"d":"0.12"},{"v":0.265496,"d":"0.27"},{"v":0.469679392533221,"d":"0.47"},{"v":-1.09025179901858,"d":"-1.09"},1,1,"down","no"]
["ENSG00000264745","TTC39C-AS1","ENST00000579713","NA","NA","NA","NA","TTC39C antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:51321]",{"v":0.093291,"d":"0.09"},{"v":0.158257,"d":"0.16"},{"v":0.58949051226802,"d":"0.59"},{"v":-0.762459501383815,"d":"-0.76"},1,1,"down","no"]
["ENSG00000236779","AL512306.1","ENST00000432698","NA","NA","NA","NA",null,0,{"v":0.053802,"d":"0.05"},"-inf","-inf",1,1,"down","no"]
["ENSG00000131059","BPIFA3","ENST00000471233","GO:0008289(lipid binding);GO:0005576(extracellular region)","NA","NA","NA","BPI fold containing family A member 3 [Source:HGNC Symbol;Acc:HGNC:16204]",{"v":9.67015719467957E-4,"d":"0.00"},0,"inf","inf",1,1,"up","no"]
["ENSG00000278662","GOLGA6L10","ENST00000621197;ENST00000619556;ENST00000610657","GO:0005794(Golgi apparatus);GO:0005794(Golgi apparatus)","NA","NA","NA","golgin A6 family-like 10 [Source:HGNC Symbol;Acc:HGNC:37228]",{"v":0.110769737433722,"d":"0.11"},{"v":0.10338929204666,"d":"0.10"},{"v":1.07138500748928,"d":"1.07"},{"v":0.0994770128444423,"d":"0.10"},1,1,"up","no"]
["ENSG00000101349","PAK5","ENST00000378429","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0005654(nucleoplasm);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0016049(cell growth);GO:0005739(mitochondrion);GO:0006915(apoptotic process);GO:0005515(protein binding);GO:0007165(signal transduction);GO:0007010(cytoskeleton organization);GO:0008283(cell proliferation);GO:0007266(Rho protein signal transduction);GO:0042981(regulation of apoptotic process);GO:0043408(regulation of MAPK cascade);GO:0016477(cell migration);GO:0007346(regulation of mitotic cell cycle);GO:0048365(Rac GTPase binding);GO:0031098(stress-activated protein kinase signaling cascade);GO:0023014(signal transduction by protein phosphorylation);GO:0032147(activation of protein kinase activity);GO:0030036(actin cytoskeleton organization);GO:0007612(learning);GO:0007613(memory);GO:0007626(locomotory behavior);GO:2001237(negative regulation of extrinsic apoptotic signaling pathway)","04014(Ras signaling pathway);04012(ErbB signaling pathway);04510(Focal adhesion);04810(Regulation of actin cytoskeleton);04660(T cell receptor signaling pathway);04360(Axon guidance);05211(Renal cell carcinoma)","K05736","EC:2.7.11.1","p21 (RAC1) activated kinase 5 [Source:HGNC Symbol;Acc:HGNC:15916]",{"v":0.0137212862649625,"d":"0.01"},{"v":0.00925646175694867,"d":"0.01"},{"v":1.48234677841802,"d":"1.48"},{"v":0.567882989465706,"d":"0.57"},1,1,"up","no"]
["ENSG00000203908","KHDC3L","ENST00000370367","GO:0003723(RNA binding);GO:0005515(protein binding);GO:0008150(biological_process);GO:0043234(protein complex)","NA","NA","NA","KH domain containing 3 like, subcortical maternal complex member [Source:HGNC Symbol;Acc:HGNC:33699]",0,{"v":0.044518,"d":"0.04"},"-inf","-inf",1,1,"down","no"]
["ENSG00000140538","NTRK3","ENST00000394480;ENST00000317501;ENST00000542733","GO:0008284(positive regulation of cell proliferation);GO:0010628(positive regulation of gene expression);GO:0001934(positive regulation of protein phosphorylation);GO:0030335(positive regulation of cell migration);GO:0032148(activation of protein kinase B activity);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0004713(protein tyrosine kinase activity);GO:0007169(transmembrane receptor protein tyrosine kinase signaling pathway);GO:0018108(peptidyl-tyrosine phosphorylation);GO:0005887(integral component of plasma membrane);GO:0005515(protein binding);GO:0004714(transmembrane receptor protein tyrosine kinase activity);GO:0005030(neurotrophin receptor activity);GO:0038179(neurotrophin signaling pathway);GO:0007275(multicellular organism development);GO:0007399(nervous system development);GO:0030154(cell differentiation);GO:0048013(ephrin receptor signaling pathway);GO:0005886(plasma membrane);GO:0007507(heart development);GO:0033138(positive regulation of peptidyl-serine phosphorylation);GO:2000251(positive regulation of actin cytoskeleton reorganization);GO:0000187(activation of MAPK activity);GO:0090630(activation of GTPase activity);GO:0001933(negative regulation of protein phosphorylation);GO:0043235(receptor complex);GO:0002039(p53 binding);GO:0043121(neurotrophin binding);GO:0050927(positive regulation of positive chemotaxis);GO:0005004(GPI-linked ephrin receptor activity);GO:0001764(neuron migration);GO:0007623(circadian rhythm);GO:0019056(modulation by virus of host transcription);GO:0042490(mechanoreceptor differentiation);GO:0043065(positive regulation of apoptotic process);GO:0045471(response to ethanol);GO:0046777(protein autophosphorylation);GO:0048665(neuron fate specification);GO:0048678(response to axon injury);GO:0048691(positive regulation of axon extension involved in regeneration);GO:0048712(negative regulation of astrocyte differentiation);GO:0051412(response to corticosterone);GO:0051965(positive regulation of synapse assembly);GO:0060548(negative regulation of cell death);GO:0070306(lens fiber cell differentiation);GO:0071300(cellular response to retinoic acid);GO:0090102(cochlea development);GO:0005737(cytoplasm);GO:0005737(cytoplasm)","04722(Neurotrophin signaling pathway);05230(Central carbon metabolism in cancer);05230(Central carbon metabolism in cancer)","K05101","EC:2.7.10.1","neurotrophic receptor tyrosine kinase 3 [Source:HGNC Symbol;Acc:HGNC:8033]",{"v":0.00257961689719626,"d":"0.00"},{"v":0.00529793940186916,"d":"0.01"},{"v":0.486909475840012,"d":"0.49"},{"v":-1.03827451743832,"d":"-1.04"},1,1,"down","no"]
["ENSG00000253301","LINC01606","ENST00000521653","NA","NA","NA","NA","long intergenic non-protein coding RNA 1606 [Source:HGNC Symbol;Acc:HGNC:51656]",{"v":3.16372830725462E-3,"d":"0.00"},0,"inf","inf",1,1,"up","no"]
["ENSG00000261889","AC108134.2","ENST00000570843","NA","NA","NA","NA",null,0,{"v":0.060995,"d":"0.06"},"-inf","-inf",1,1,"down","no"]
["ENSG00000175356","SCUBE2","ENST00000309263;ENST00000520467","GO:0005509(calcium ion binding);GO:0005576(extracellular region);GO:0005615(extracellular space);GO:0009986(cell surface);GO:0007165(signal transduction);GO:0030154(cell differentiation);GO:0030154(cell differentiation)","NA","NA","NA","signal peptide, CUB domain and EGF like domain containing 2 [Source:HGNC Symbol;Acc:HGNC:30425]",{"v":0.00992939160445133,"d":"0.01"},{"v":0.0256645234540076,"d":"0.03"},{"v":0.38689171931228,"d":"0.39"},{"v":-1.36999824394277,"d":"-1.37"},1,1,"down","no"]
["ENSG00000275613","AC243830.1","ENST00000610398","NA","NA","NA","NA",null,{"v":0.112218,"d":"0.11"},0,"inf","inf",1,1,"up","no"]
["MSTRG.6116","HPR","ENST00000540303;ENST00000566168","GO:0005576(extracellular region);GO:0006898(receptor-mediated endocytosis);GO:0030492(hemoglobin binding);GO:0070062(extracellular exosome);GO:0072562(blood microparticle);GO:0034366(spherical high-density lipoprotein particle);GO:0006508(proteolysis);GO:0004252(serine-type endopeptidase activity);GO:0004252(serine-type endopeptidase activity)","05143(African trypanosomiasis);05143(African trypanosomiasis)","K14477","NA","haptoglobin-related protein [Source:HGNC Symbol;Acc:HGNC:5156]",0,{"v":0.120639560248447,"d":"0.12"},"-inf","-inf",1,1,"down","no"]
["ENSG00000158516","CPA2","ENST00000222481","GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0016787(hydrolase activity);GO:0008233(peptidase activity);GO:0006508(proteolysis);GO:0005576(extracellular region);GO:0004181(metallocarboxypeptidase activity);GO:0004180(carboxypeptidase activity);GO:0008237(metallopeptidase activity);GO:0005615(extracellular space);GO:0007039(protein catabolic process in the vacuole);GO:0005773(vacuole)","04972(Pancreatic secretion);04974(Protein digestion and absorption)","K01298","EC:3.4.17.15","carboxypeptidase A2 [Source:HGNC Symbol;Acc:HGNC:2297]",{"v":0.0119907763805358,"d":"0.01"},{"v":0.02049,"d":"0.02"},{"v":0.585201385092035,"d":"0.59"},{"v":-0.772994910744104,"d":"-0.77"},1,1,"down","no"]
["MSTRG.4464","TEX21P","ENST00000641725;ENST00000447107;ENST00000641479;ENST00000641577","NA","NA","NA","NA","testis expressed 21, pseudogene [Source:HGNC Symbol;Acc:HGNC:35455]",{"v":0.115268257432005,"d":"0.12"},{"v":0.0213021265022138,"d":"0.02"},{"v":5.41111505558029,"d":"5.41"},{"v":2.43592591741543,"d":"2.44"},1,1,"up","no"]
["ENSG00000141198","TOM1L1","ENST00000573607;ENST00000574318;ENST00000574653;ENST00000575882;ENST00000575333","GO:0006810(transport);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0006886(intracellular protein transport);GO:0015031(protein transport);GO:0005794(Golgi apparatus);GO:0005622(intracellular);GO:0005515(protein binding);GO:0007165(signal transduction);GO:0005768(endosome);GO:0070062(extracellular exosome);GO:0019901(protein kinase binding);GO:0010008(endosome membrane);GO:0017124(SH3 domain binding);GO:0030295(protein kinase activator activity);GO:0005764(lysosome);GO:0005829(cytosol);GO:0005795(Golgi stack);GO:0045839(negative regulation of mitotic nuclear division);GO:0030276(clathrin binding);GO:0043130(ubiquitin binding);GO:0031954(positive regulation of protein autophosphorylation);GO:0032147(activation of protein kinase activity);GO:0043162(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway);GO:0043162(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)","NA","NA","NA","target of myb1 like 1 membrane trafficking protein [Source:HGNC Symbol;Acc:HGNC:11983]",{"v":0.0601162827491409,"d":"0.06"},{"v":0.0159653314089347,"d":"0.02"},{"v":3.76542654889694,"d":"3.77"},{"v":1.91281330317656,"d":"1.91"},1,1,"up","no"]
["ENSG00000282542","AC008993.1","ENST00000632280","NA","NA","NA","NA",null,{"v":0.528593,"d":"0.53"},0,"inf","inf",1,1,"up","no"]
["ENSG00000243135","UGT1A3","ENST00000482026","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016740(transferase activity);GO:0016757(transferase activity, transferring glycosyl groups);GO:0008152(metabolic process);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0042803(protein homodimerization activity);GO:0016758(transferase activity, transferring hexosyl groups);GO:0015020(glucuronosyltransferase activity);GO:0043231(intracellular membrane-bounded organelle);GO:0046982(protein heterodimerization activity);GO:0001972(retinoic acid binding);GO:0042573(retinoic acid metabolic process);GO:0052695(cellular glucuronidation);GO:0052696(flavonoid glucuronidation);GO:0052697(xenobiotic glucuronidation)","00040(Pentose and glucuronate interconversions);00053(Ascorbate and aldarate metabolism);00140(Steroid hormone biosynthesis);00830(Retinol metabolism);00860(Porphyrin and chlorophyll metabolism);00980(Metabolism of xenobiotics by cytochrome P450);00982(Drug metabolism - cytochrome P450);00983(Drug metabolism - other enzymes);05204(Chemical carcinogenesis)","K00699","EC:2.4.1.17","UDP glucuronosyltransferase family 1 member A3 [Source:HGNC Symbol;Acc:HGNC:12535]",{"v":0.091544,"d":"0.09"},0,"inf","inf",1,1,"up","no"]
["ENSG00000197275","RAD54B","ENST00000336148;ENST00000523192;ENST00000297592;ENST00000463267;ENST00000518358","GO:0005634(nucleus);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0016787(hydrolase activity);GO:0004386(helicase activity);GO:0032508(DNA duplex unwinding);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0006281(DNA repair);GO:0006974(cellular response to DNA damage stimulus);GO:0007131(reciprocal meiotic recombination);GO:0003724(RNA helicase activity);GO:0003678(DNA helicase activity);GO:0000724(double-strand break repair via homologous recombination);GO:0006312(mitotic recombination);GO:0015616(DNA translocase activity);GO:0015616(DNA translocase activity)","03440(Homologous recombination);03440(Homologous recombination)","K10877","EC:3.6.4.-","RAD54 homolog B (S. cerevisiae) [Source:HGNC Symbol;Acc:HGNC:17228]",{"v":0.168760023527197,"d":"0.17"},{"v":0.110460046113307,"d":"0.11"},{"v":1.52779244138725,"d":"1.53"},{"v":0.611448559001346,"d":"0.61"},1,1,"up","no"]
["ENSG00000132170","PPARG","ENST00000477039;ENST00000397026;ENST00000309576","GO:0051091(positive regulation of sequence-specific DNA binding transcription factor activity);GO:0006919(activation of cysteine-type endopeptidase activity involved in apoptotic process);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0005634(nucleus);GO:0048662(negative regulation of smooth muscle cell proliferation);GO:0005737(cytoplasm);GO:0043231(intracellular membrane-bounded organelle);GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0043565(sequence-specific DNA binding);GO:0005515(protein binding);GO:0003707(steroid hormone receptor activity);GO:0004879(RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding);GO:0030522(intracellular receptor signaling pathway);GO:0043401(steroid hormone mediated signaling pathway);GO:0048511(rhythmic process);GO:0030374(ligand-dependent nuclear receptor transcription coactivator activity);GO:0042802(identical protein binding);GO:0007186(G-protein coupled receptor signaling pathway);GO:0005654(nucleoplasm);GO:0003682(chromatin binding);GO:0005829(cytosol);GO:0019899(enzyme binding);GO:0045087(innate immune response);GO:0008134(transcription factor binding);GO:0045893(positive regulation of transcription, DNA-templated);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0006367(transcription initiation from RNA polymerase II promoter);GO:0043234(protein complex);GO:0045892(negative regulation of transcription, DNA-templated);GO:0044212(transcription regulatory region DNA binding);GO:0090575(RNA polymerase II transcription factor complex);GO:0006629(lipid metabolic process);GO:0001046(core promoter sequence-specific DNA binding);GO:0048469(cell maturation);GO:0046982(protein heterodimerization activity);GO:0042752(regulation of circadian rhythm);GO:0050872(white fat cell differentiation);GO:0007584(response to nutrient);GO:0032869(cellular response to insulin stimulus);GO:0007165(signal transduction);GO:0008217(regulation of blood pressure);GO:0042593(glucose homeostasis);GO:0032526(response to retinoic acid);GO:0010745(negative regulation of macrophage derived foam cell differentiation);GO:0010887(negative regulation of cholesterol storage);GO:0055098(response to low-density lipoprotein particle);GO:0008022(protein C-terminus binding);GO:0008144(drug binding);GO:0042953(lipoprotein transport);GO:0055088(lipid homeostasis);GO:0051393(alpha-actinin binding);GO:0003690(double-stranded DNA binding);GO:0046965(retinoid X receptor binding);GO:0030855(epithelial cell differentiation);GO:0042277(peptide binding);GO:0045165(cell fate commitment);GO:0060850(regulation of transcription involved in cell fate commitment);GO:0050692(DBD domain binding);GO:0050693(LBD domain binding);GO:0010871(negative regulation of receptor biosynthetic process);GO:0033613(activating transcription factor binding);GO:0043621(protein self-association);GO:0004955(prostaglandin receptor activity);GO:0050544(arachidonic acid binding);GO:0001890(placenta development);GO:0010742(macrophage derived foam cell differentiation);GO:0010891(negative regulation of sequestering of triglyceride);GO:0015909(long-chain fatty acid transport);GO:0030224(monocyte differentiation);GO:0033993(response to lipid);GO:0035357(peroxisome proliferator activated receptor signaling pathway);GO:0043388(positive regulation of DNA binding);GO:0045600(positive regulation of fat cell differentiation);GO:0045713(low-density lipoprotein particle receptor biosynthetic process);GO:0060336(negative regulation of interferon-gamma-mediated signaling pathway);GO:0060694(regulation of cholesterol transporter activity);GO:0019903(protein phosphatase binding);GO:0030331(estrogen receptor binding);GO:0002674(negative regulation of acute inflammatory response);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0007507(heart development);GO:0008285(negative regulation of cell proliferation);GO:0009409(response to cold);GO:0009612(response to mechanical stimulus);GO:0010033(response to organic substance);GO:0014070(response to organic cyclic compound);GO:0019216(regulation of lipid metabolic process);GO:0019395(fatty acid oxidation);GO:0030308(negative regulation of cell growth);GO:0031000(response to caffeine);GO:0031100(animal organ regeneration);GO:0032966(negative regulation of collagen biosynthetic process);GO:0033189(response to vitamin A);GO:0035902(response to immobilization stress);GO:0042493(response to drug);GO:0042594(response to starvation);GO:0043065(positive regulation of apoptotic process);GO:0043627(response to estrogen);GO:0045598(regulation of fat cell differentiation);GO:0046321(positive regulation of fatty acid oxidation);GO:0048714(positive regulation of oligodendrocyte differentiation);GO:0051974(negative regulation of telomerase activity);GO:0060100(positive regulation of phagocytosis, engulfment);GO:0071300(cellular response to retinoic acid);GO:0071306(cellular response to vitamin E);GO:0071379(cellular response to prostaglandin stimulus);GO:0071380(cellular response to prostaglandin E stimulus);GO:0071455(cellular response to hyperoxia);GO:1901558(response to metformin);GO:2000230(negative regulation of pancreatic stellate cell proliferation);GO:0048471(perinuclear region of cytoplasm);GO:0048471(perinuclear region of cytoplasm)","04152(AMPK signaling pathway);03320(PPAR signaling pathway);04380(Osteoclast differentiation);04211(Longevity regulating pathway - mammal);05200(Pathways in cancer);05202(Transcriptional misregulation in cancers);05216(Thyroid cancer);05016(Huntington's disease);05016(Huntington's disease)","K08530","NA","peroxisome proliferator activated receptor gamma [Source:HGNC Symbol;Acc:HGNC:9236]",{"v":0.122344495798319,"d":"0.12"},{"v":0.0947602419673752,"d":"0.09"},{"v":1.29109522367451,"d":"1.29"},{"v":0.368595409364499,"d":"0.37"},1,1,"up","no"]
["ENSG00000227471","AKR1B15","ENST00000457545;ENST00000467156","GO:0005737(cytoplasm);GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0005829(cytosol);GO:0005739(mitochondrion);GO:0005759(mitochondrial matrix);GO:0004303(estradiol 17-beta-dehydrogenase activity);GO:0006703(estrogen biosynthetic process);GO:0006703(estrogen biosynthetic process)","NA","NA","NA","aldo-keto reductase family 1 member B15 [Source:HGNC Symbol;Acc:HGNC:37281]",0,{"v":0.0305017413533835,"d":"0.03"},"-inf","-inf",1,1,"down","no"]
["ENSG00000258803","AL355103.1","ENST00000557246","NA","NA","NA","NA",null,{"v":0.022861,"d":"0.02"},{"v":0.020496,"d":"0.02"},{"v":1.11538836846214,"d":"1.12"},{"v":0.157546131399161,"d":"0.16"},1,1,"up","no"]
["MSTRG.12371","LINC01024","ENST00000499203;ENST00000521133;ENST00000523452","NA","NA","NA","NA","long intergenic non-protein coding RNA 1024 [Source:HGNC Symbol;Acc:HGNC:49009]",{"v":0.109489396626926,"d":"0.11"},{"v":0.136984938354173,"d":"0.14"},{"v":0.799280548229634,"d":"0.80"},{"v":-0.323226115515992,"d":"-0.32"},1,1,"down","no"]
["ENSG00000234884","AL022329.1","ENST00000453811;ENST00000422876","NA","NA","NA","NA",null,{"v":0.0187412396166134,"d":"0.02"},0,"inf","inf",1,1,"up","no"]
["ENSG00000159784","FAM131B","ENST00000409408;ENST00000521347;ENST00000519161","GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0005515(protein binding);GO:0005515(protein binding)","NA","NA","NA","family with sequence similarity 131 member B [Source:HGNC Symbol;Acc:HGNC:22202]",{"v":0.179174474650078,"d":"0.18"},{"v":0.0419309636080871,"d":"0.04"},{"v":4.27308268717014,"d":"4.27"},{"v":2.09527723445785,"d":"2.10"},1,1,"up","no"]
["ENSG00000242353","RPL12P30","ENST00000488389","NA","NA","NA","NA","ribosomal protein L12 pseudogene 30 [Source:HGNC Symbol;Acc:HGNC:35970]",0,0,1,0,1,1,"no","no"]
["ENSG00000259015","AL442663.4","ENST00000555304","NA","NA","NA","NA",null,{"v":0.160901,"d":"0.16"},{"v":0.231295,"d":"0.23"},{"v":0.695652737845608,"d":"0.70"},{"v":-0.523560786532335,"d":"-0.52"},1,1,"down","no"]
["ENSG00000197123","ZNF679","ENST00000421025","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0005622(intracellular);GO:0005515(protein binding)","NA","NA","NA","zinc finger protein 679 [Source:HGNC Symbol;Acc:HGNC:28650]",{"v":0.021839,"d":"0.02"},{"v":0.005532,"d":"0.01"},{"v":3.94775849602314,"d":"3.95"},{"v":1.98103373567913,"d":"1.98"},1,1,"up","no"]
["ENSG00000260773","AC055855.2","ENST00000565993","NA","NA","NA","NA",null,{"v":0.193118,"d":"0.19"},0,"inf","inf",1,1,"up","no"]
["ENSG00000279670","AL359922.3","ENST00000624779","NA","NA","NA","NA",null,{"v":0.03078,"d":"0.03"},{"v":0.113377,"d":"0.11"},{"v":0.271483634246805,"d":"0.27"},{"v":-1.88106286371821,"d":"-1.88"},1,1,"down","no"]
["ENSG00000221971","TTC4P1","ENST00000427137","NA","NA","NA","NA","tetratricopeptide repeat domain 4 pseudogene 1 [Source:HGNC Symbol;Acc:HGNC:12395]",{"v":0.177554,"d":"0.18"},{"v":0.096659,"d":"0.10"},{"v":1.83691120330233,"d":"1.84"},{"v":0.87728188793447,"d":"0.88"},1,1,"up","no"]
["ENSG00000174325","DIRC1","ENST00000308100","NA","NA","NA","NA","disrupted in renal carcinoma 1 [Source:HGNC Symbol;Acc:HGNC:15760]",{"v":0.048513,"d":"0.05"},{"v":0.043996,"d":"0.04"},{"v":1.10266842440222,"d":"1.10"},{"v":0.140999033553155,"d":"0.14"},1,1,"up","no"]
["ENSG00000260388","LINC00562","ENST00000566385","NA","NA","NA","NA","long intergenic non-protein coding RNA 562 [Source:HGNC Symbol;Acc:HGNC:43706]",{"v":0.062432,"d":"0.06"},{"v":0.017425,"d":"0.02"},{"v":3.5828981348637,"d":"3.58"},{"v":1.84112702696588,"d":"1.84"},1,1,"up","no"]
["MSTRG.2388","AP000781.1","ENST00000534162","NA","NA","NA","NA",null,{"v":0.16789,"d":"0.17"},{"v":0.126555,"d":"0.13"},{"v":1.32661688593892,"d":"1.33"},{"v":0.407751794552909,"d":"0.41"},1,1,"up","no"]
["ENSG00000185739","SRL","ENST00000572111","GO:0005525(GTP binding);GO:0016529(sarcoplasmic reticulum);GO:0033018(sarcoplasmic reticulum lumen)","NA","NA","NA","sarcalumenin [Source:HGNC Symbol;Acc:HGNC:11295]",{"v":0.026087037530691,"d":"0.03"},{"v":0.0237667962118555,"d":"0.02"},{"v":1.0976253298153,"d":"1.10"},{"v":0.13438567997,"d":"0.13"},1,1,"up","no"]
["ENSG00000109321","AREG","ENST00000395748","GO:0005615(extracellular space);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0008083(growth factor activity);GO:0005515(protein binding);GO:0005125(cytokine activity);GO:0000139(Golgi membrane);GO:0005789(endoplasmic reticulum membrane);GO:0009986(cell surface);GO:0007267(cell-cell signaling);GO:0006888(ER to Golgi vesicle-mediated transport);GO:0008283(cell proliferation);GO:0048208(COPII vesicle coating);GO:0012507(ER to Golgi transport vesicle membrane);GO:0033116(endoplasmic reticulum-Golgi intermediate compartment membrane);GO:0007173(epidermal growth factor receptor signaling pathway);GO:0007186(G-protein coupled receptor signaling pathway);GO:0045740(positive regulation of DNA replication);GO:0008284(positive regulation of cell proliferation);GO:0005154(epidermal growth factor receptor binding);GO:0014009(glial cell proliferation);GO:0014070(response to organic cyclic compound);GO:0031175(neuron projection development);GO:0032355(response to estradiol);GO:0042327(positive regulation of phosphorylation);GO:0042542(response to hydrogen peroxide);GO:0043434(response to peptide hormone);GO:0045668(negative regulation of osteoblast differentiation);GO:0050731(positive regulation of peptidyl-tyrosine phosphorylation);GO:0051384(response to glucocorticoid);GO:0051591(response to cAMP);GO:0060598(dichotomous subdivision of terminal units involved in mammary gland duct morphogenesis);GO:0060744(mammary gland branching involved in thelarche);GO:0060749(mammary gland alveolus development);GO:0060750(epithelial cell proliferation involved in mammary gland duct elongation);GO:0005622(intracellular);GO:0005634(nucleus);GO:0005737(cytoplasm)","04012(ErbB signaling pathway);04390(Hippo signaling pathway)","K09782","NA","amphiregulin [Source:HGNC Symbol;Acc:HGNC:651]",{"v":0.0607178640776699,"d":"0.06"},{"v":0.347807961165049,"d":"0.35"},{"v":0.174572956508195,"d":"0.17"},{"v":-2.51809800976509,"d":"-2.52"},1,1,"down","no"]
["ENSG00000255666","AP000943.2","ENST00000544019;ENST00000541293","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000261934","PCDHGA9","ENST00000616887","GO:0003723(RNA binding);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005509(calcium ion binding);GO:0007155(cell adhesion);GO:0007156(homophilic cell adhesion via plasma membrane adhesion molecules);GO:0005886(plasma membrane);GO:0005887(integral component of plasma membrane);GO:0007399(nervous system development);GO:0007267(cell-cell signaling);GO:0007283(spermatogenesis)","NA","NA","NA","protocadherin gamma subfamily A, 9 [Source:HGNC Symbol;Acc:HGNC:8707]",0,{"v":0.0192143070120025,"d":"0.02"},"-inf","-inf",1,1,"down","no"]
["MSTRG.11287","MBNL1-AS1","ENST00000608395","NA","NA","NA","NA","MBNL1 antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:44584]",{"v":0.196816,"d":"0.20"},{"v":0.063526,"d":"0.06"},{"v":3.09819601423039,"d":"3.10"},{"v":1.63142842231093,"d":"1.63"},1,1,"up","no"]
["MSTRG.8931","AC103563.7","ENST00000448734","NA","NA","NA","NA",null,{"v":0.350094,"d":"0.35"},{"v":0.420817,"d":"0.42"},{"v":0.831938823764249,"d":"0.83"},{"v":-0.265450650531678,"d":"-0.27"},1,1,"down","no"]
["ENSG00000226869","LHFPL3-AS1","ENST00000449764","NA","NA","NA","NA","LHFPL3 antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:40341]",{"v":0.00394652451464297,"d":"0.00"},0,"inf","inf",1,1,"up","no"]
["MSTRG.635","DIRAS3","ENST00000370981","GO:0005622(intracellular);GO:0016020(membrane);GO:0005525(GTP binding);GO:0000166(nucleotide binding);GO:0007165(signal transduction);GO:0003924(GTPase activity);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0007264(small GTPase mediated signal transduction);GO:0000079(regulation of cyclin-dependent protein serine/threonine kinase activity);GO:0006349(regulation of gene expression by genetic imprinting)","NA","NA","NA","DIRAS family GTPase 3 [Source:HGNC Symbol;Acc:HGNC:687]",0,0,1,0,1,1,"no","no"]
["MSTRG.6379","AC027763.1","ENST00000572223","NA","NA","NA","NA",null,{"v":0.071392,"d":"0.07"},0,"inf","inf",1,1,"up","no"]
["MSTRG.12210","MEF2C-AS1","ENST00000514011;ENST00000508718;ENST00000639552;ENST00000511876;ENST00000511100;ENST00000514794;ENST00000506665;ENST00000514571;ENST00000509179;ENST00000513704;ENST00000508742;ENST00000514092;ENST00000512585","NA","NA","NA","NA","MEF2C antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:48908]",{"v":0.0486236755244755,"d":"0.05"},{"v":0.170844225810553,"d":"0.17"},{"v":0.284608246452495,"d":"0.28"},{"v":-1.81295063069071,"d":"-1.81"},1,1,"down","no"]
["ENSG00000233706","AL353689.2","ENST00000433837","NA","NA","NA","NA",null,{"v":0.016745,"d":"0.02"},0,"inf","inf",1,1,"up","no"]
["ENSG00000243896","OR2A7","ENST00000493325;ENST00000641841","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0004930(G-protein coupled receptor activity);GO:0007186(G-protein coupled receptor signaling pathway);GO:0005886(plasma membrane);GO:0004871(signal transducer activity);GO:0007165(signal transduction);GO:0004984(olfactory receptor activity);GO:0007608(sensory perception of smell);GO:0050896(response to stimulus);GO:0050911(detection of chemical stimulus involved in sensory perception of smell);GO:0004888(transmembrane signaling receptor activity);GO:0050907(detection of chemical stimulus involved in sensory perception);GO:0050907(detection of chemical stimulus involved in sensory perception)","04740(Olfactory transduction);04740(Olfactory transduction)","K04257","NA","olfactory receptor family 2 subfamily A member 7 [Source:HGNC Symbol;Acc:HGNC:8234]",{"v":0.27213805204461,"d":"0.27"},0,"inf","inf",1,1,"up","no"]
["ENSG00000279685","MAPT-IT1","ENST00000624111","NA","NA","NA","NA","MAPT intronic transcript 1 [Source:HGNC Symbol;Acc:HGNC:43741]",{"v":0.034086,"d":"0.03"},{"v":0.014623,"d":"0.01"},{"v":2.33098543390549,"d":"2.33"},{"v":1.22093998923813,"d":"1.22"},1,1,"up","no"]
["ENSG00000168907","PLA2G4F","ENST00000397272","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0046872(metal ion binding);GO:0016787(hydrolase activity);GO:0005765(lysosomal membrane);GO:0004620(phospholipase activity);GO:0006629(lipid metabolic process);GO:0008152(metabolic process);GO:0009395(phospholipid catabolic process);GO:0016042(lipid catabolic process);GO:0005829(cytosol);GO:0004623(phospholipase A2 activity);GO:0005764(lysosome);GO:0036148(phosphatidylglycerol acyl-chain remodeling);GO:0036149(phosphatidylinositol acyl-chain remodeling);GO:0036150(phosphatidylserine acyl-chain remodeling);GO:0036151(phosphatidylcholine acyl-chain remodeling);GO:0036152(phosphatidylethanolamine acyl-chain remodeling);GO:0004622(lysophospholipase activity);GO:0008970(phosphatidylcholine 1-acylhydrolase activity);GO:0006644(phospholipid metabolic process);GO:0047498(calcium-dependent phospholipase A2 activity);GO:0001516(prostaglandin biosynthetic process);GO:0015908(fatty acid transport);GO:0050482(arachidonic acid secretion);GO:0071236(cellular response to antibiotic);GO:0071407(cellular response to organic cyclic compound);GO:0031982(vesicle);GO:0032587(ruffle membrane)","00564(Glycerophospholipid metabolism);00565(Ether lipid metabolism);00590(Arachidonic acid metabolism);00591(Linoleic acid metabolism);00592(alpha-Linolenic acid metabolism);04014(Ras signaling pathway);04010(MAPK signaling pathway);04370(VEGF signaling pathway);04072(Phospholipase D signaling pathway);04217(Necroptosis);04611(Platelet activation);04664(Fc epsilon RI signaling pathway);04666(Fc gamma R-mediated phagocytosis);04912(GnRH signaling pathway);04913(Ovarian Steroidogenesis);04921(Oxytocin signaling pathway);04270(Vascular smooth muscle contraction);04724(Glutamatergic synapse);04726(Serotonergic synapse);04730(Long-term depression);04750(Inflammatory mediator regulation of TRP channels);05231(Choline metabolism in cancer)","K16342","EC:3.1.1.4","phospholipase A2 group IVF [Source:HGNC Symbol;Acc:HGNC:27396]",{"v":0.0265764700966738,"d":"0.03"},{"v":0.00799463722759299,"d":"0.01"},{"v":3.32428718653384,"d":"3.32"},{"v":1.73304502250865,"d":"1.73"},1,1,"up","no"]
["ENSG00000260123","AC013565.1","ENST00000565938","NA","NA","NA","NA",null,0,{"v":0.027751,"d":"0.03"},"-inf","-inf",1,1,"down","no"]
["ENSG00000256553","TRAV1-2","ENST00000390423","NA","NA","NA","NA","T-cell receptor alpha variable 1-2 [Source:HGNC Symbol;Acc:HGNC:12102]",{"v":0.146902,"d":"0.15"},{"v":1.078442,"d":"1.08"},{"v":0.136216875826424,"d":"0.14"},{"v":-2.87602264584808,"d":"-2.88"},1,1,"down","no"]
["ENSG00000224920","TACC1P1","ENST00000425494","NA","NA","NA","NA","transforming acidic coiled-coil containing protein 1 pseudogene 1 [Source:HGNC Symbol;Acc:HGNC:44974]",0,{"v":0.031378,"d":"0.03"},"-inf","-inf",1,1,"down","no"]
["MSTRG.12511","NIPAL4","ENST00000311946;ENST00000435489;ENST00000519150","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0006811(ion transport);GO:0015095(magnesium ion transmembrane transporter activity);GO:0015693(magnesium ion transport);GO:1903830(magnesium ion transmembrane transport);GO:1903830(magnesium ion transmembrane transport)","NA","NA","NA","NIPA like domain containing 4 [Source:HGNC Symbol;Acc:HGNC:28018]",{"v":0.0911265926806084,"d":"0.09"},{"v":0.0692091544676806,"d":"0.07"},{"v":1.31668409159893,"d":"1.32"},{"v":0.396909245249871,"d":"0.40"},1,1,"up","no"]
["ENSG00000279118","AC093535.2","ENST00000624769","NA","NA","NA","NA",null,{"v":0.064971,"d":"0.06"},{"v":0.039099,"d":"0.04"},{"v":1.66170490293869,"d":"1.66"},{"v":0.732664201081074,"d":"0.73"},1,1,"up","no"]
["ENSG00000250844","USP17L18","ENST00000619296","GO:0005634(nucleus);GO:0016579(protein deubiquitination);GO:0016787(hydrolase activity);GO:0005783(endoplasmic reticulum);GO:0008233(peptidase activity);GO:0008234(cysteine-type peptidase activity);GO:0006508(proteolysis);GO:0006511(ubiquitin-dependent protein catabolic process);GO:0036459(thiol-dependent ubiquitinyl hydrolase activity)","NA","NA","NA","ubiquitin specific peptidase 17-like family member 18 [Source:HGNC Symbol;Acc:HGNC:44446]",{"v":1.054E-3,"d":"0.00"},0,"inf","inf",1,1,"up","no"]
["MSTRG.10348","CABP7","ENST00000216144","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0046872(metal ion binding);GO:0005509(calcium ion binding);GO:0005794(Golgi apparatus);GO:0005886(plasma membrane);GO:0048471(perinuclear region of cytoplasm);GO:0032588(trans-Golgi network membrane)","NA","NA","NA","calcium binding protein 7 [Source:HGNC Symbol;Acc:HGNC:20834]",{"v":0.042142,"d":"0.04"},{"v":0.013906,"d":"0.01"},{"v":3.03049043578312,"d":"3.03"},{"v":1.59955128941321,"d":"1.60"},1,1,"up","no"]
["ENSG00000258181","AC008083.3","ENST00000547777;ENST00000552063","NA","NA","NA","NA",null,{"v":0.228332196078431,"d":"0.23"},{"v":0.399703423529412,"d":"0.40"},{"v":0.571254041464644,"d":"0.57"},{"v":-0.807795628011403,"d":"-0.81"},1,1,"down","no"]
["ENSG00000259005","AC005479.2","ENST00000556370","NA","NA","NA","NA",null,0,{"v":1.291E-3,"d":"0.00"},"-inf","-inf",1,1,"down","no"]
["ENSG00000279103","AC138470.1","ENST00000624638","NA","NA","NA","NA",null,{"v":0.027096,"d":"0.03"},{"v":0.167231,"d":"0.17"},{"v":0.16202737530721,"d":"0.16"},{"v":-2.6256905108923,"d":"-2.63"},1,1,"down","no"]
["ENSG00000230312","AC234782.1","ENST00000451950","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000205363","C15orf59","ENST00000379822;ENST00000569673","NA","NA","NA","NA","chromosome 15 open reading frame 59 [Source:HGNC Symbol;Acc:HGNC:33753]",{"v":0.007664,"d":"0.01"},{"v":0.0105273397231097,"d":"0.01"},{"v":0.728009183856385,"d":"0.73"},{"v":-0.457971444709968,"d":"-0.46"},1,1,"down","no"]
["ENSG00000151276","MAGI1","ENST00000330909","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0005654(nucleoplasm);GO:0005886(plasma membrane);GO:0032947(protein complex scaffold);GO:0030054(cell junction);GO:0042995(cell projection);GO:0005515(protein binding);GO:0005923(bicellular tight junction);GO:0005912(adherens junction);GO:0007155(cell adhesion);GO:0007166(cell surface receptor signaling pathway);GO:0006461(protein complex assembly);GO:0005911(cell-cell junction);GO:0008022(protein C-terminus binding);GO:0051393(alpha-actinin binding);GO:0070997(neuron death);GO:0005634(nucleus)","04015(Rap1 signaling pathway);04530(Tight junction);05165(Human papillomavirus infection)","K05631","NA","membrane associated guanylate kinase, WW and PDZ domain containing 1 [Source:HGNC Symbol;Acc:HGNC:946]",{"v":0.0148630998368959,"d":"0.01"},{"v":0.0072450450682462,"d":"0.01"},{"v":2.0514848005623,"d":"2.05"},{"v":1.03666846535176,"d":"1.04"},1,1,"up","no"]
["ENSG00000148950","IMMP1L","ENST00000532668;ENST00000534812;ENST00000526776;ENST00000532287;ENST00000528161;ENST00000530023;ENST00000529749;ENST00000278200;ENST00000533642;ENST00000533512;ENST00000531331;ENST00000532624","GO:0016020(membrane);GO:0016787(hydrolase activity);GO:0005743(mitochondrial inner membrane);GO:0005739(mitochondrion);GO:0008233(peptidase activity);GO:0006508(proteolysis);GO:0008236(serine-type peptidase activity);GO:0003674(molecular_function);GO:0008150(biological_process);GO:0006627(protein processing involved in protein targeting to mitochondrion);GO:0006465(signal peptide processing);GO:0033108(mitochondrial respiratory chain complex assembly);GO:0042720(mitochondrial inner membrane peptidase complex);GO:0042720(mitochondrial inner membrane peptidase complex)","03060(Protein export);03060(Protein export)","K09647","EC:3.4.21.-","inner mitochondrial membrane peptidase subunit 1 [Source:HGNC Symbol;Acc:HGNC:26317]",{"v":0.154321411352488,"d":"0.15"},{"v":0.22917875648213,"d":"0.23"},{"v":0.673366998413403,"d":"0.67"},{"v":-0.57053507819465,"d":"-0.57"},1,1,"down","no"]
["MSTRG.5138","AC090515.1","ENST00000465295","NA","NA","NA","NA",null,0,{"v":0.091695,"d":"0.09"},"-inf","-inf",1,1,"down","no"]
["MSTRG.7731","AC011444.4","ENST00000586415","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000115226","FNDC4","ENST00000264703;ENST00000491414","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005783(endoplasmic reticulum);GO:0005886(plasma membrane);GO:0005886(plasma membrane)","NA","NA","NA","fibronectin type III domain containing 4 [Source:HGNC Symbol;Acc:HGNC:20239]",{"v":0.0162523107971746,"d":"0.02"},{"v":0.109187476286579,"d":"0.11"},{"v":0.14884775571255,"d":"0.15"},{"v":-2.74809062572514,"d":"-2.75"},1,1,"down","no"]
["ENSG00000217801","AL390719.1","ENST00000427998;ENST00000412397","NA","NA","NA","NA",null,{"v":0.173248516351912,"d":"0.17"},{"v":0.104156673883003,"d":"0.10"},{"v":1.66334532289806,"d":"1.66"},{"v":0.734087713973588,"d":"0.73"},1,1,"up","no"]
["ENSG00000284294","AC007326.5","ENST00000623496;ENST00000638287","NA","NA","NA","NA",null,{"v":5.49364182692308E-4,"d":"0.00"},{"v":0.0175995132211538,"d":"0.02"},{"v":0.0312147373503489,"d":"0.03"},{"v":-5.00162886317441,"d":"-5.00"},1,1,"down","no"]
["ENSG00000198185","ZNF334","ENST00000347606","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0005622(intracellular);GO:0005515(protein binding);GO:0003700(transcription factor activity, sequence-specific DNA binding)","NA","NA","NA","zinc finger protein 334 [Source:HGNC Symbol;Acc:HGNC:15806]",{"v":0.00671414566642389,"d":"0.01"},{"v":0.0132917305171158,"d":"0.01"},{"v":0.505137059299996,"d":"0.51"},{"v":-0.985253206143312,"d":"-0.99"},1,1,"down","no"]
["ENSG00000197627","UBE2Q2P12","ENST00000414573","NA","NA","NA","NA","ubiquitin conjugating enzyme E2 Q2 pseudogene 12 [Source:HGNC Symbol;Acc:HGNC:49523]",0,{"v":0.020128,"d":"0.02"},"-inf","-inf",1,1,"down","no"]
["ENSG00000164695","CHMP4C","ENST00000297265","GO:0006810(transport);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0015031(protein transport);GO:0005829(cytosol);GO:0042803(protein homodimerization activity);GO:0005515(protein binding);GO:0007034(vacuolar transport);GO:0030496(midbody);GO:0005768(endosome);GO:0031902(late endosome membrane);GO:0032466(negative regulation of cytokinesis);GO:0070062(extracellular exosome);GO:0016197(endosomal transport);GO:0016236(macroautophagy);GO:0019058(viral life cycle);GO:0036258(multivesicular body assembly);GO:0039702(viral budding via host ESCRT complex);GO:0007080(mitotic metaphase plate congression);GO:0010824(regulation of centrosome duplication);GO:0000920(cell separation after cytokinesis);GO:0006997(nucleus organization);GO:0050792(regulation of viral process);GO:1901673(regulation of mitotic spindle assembly);GO:1902188(positive regulation of viral release from host cell);GO:0000815(ESCRT III complex);GO:0090611(ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway);GO:0090543(Flemming body);GO:0009838(abscission);GO:0044878(mitotic cytokinesis checkpoint)","04144(Endocytosis);04217(Necroptosis)","K12194","NA","charged multivesicular body protein 4C [Source:HGNC Symbol;Acc:HGNC:30599]",0,0,1,0,1,1,"no","no"]
["MSTRG.1998","NANOS1","ENST00000425699","GO:0003723(RNA binding);GO:0005737(cytoplasm);GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0005515(protein binding);GO:0048471(perinuclear region of cytoplasm);GO:0006417(regulation of translation);GO:0017148(negative regulation of translation);GO:0016477(cell migration);GO:0030371(translation repressor activity);GO:1900153(positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay);GO:0010608(posttranscriptional regulation of gene expression);GO:0010631(epithelial cell migration);GO:0001558(regulation of cell growth);GO:0001894(tissue homeostasis);GO:0098749(cerebellar neuron development)","NA","NA","NA","nanos C2HC-type zinc finger 1 [Source:HGNC Symbol;Acc:HGNC:23044]",{"v":0.012114,"d":"0.01"},0,"inf","inf",1,1,"up","no"]
["ENSG00000204961","PCDHA9","ENST00000532602;ENST00000378122","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005509(calcium ion binding);GO:0007155(cell adhesion);GO:0007156(homophilic cell adhesion via plasma membrane adhesion molecules);GO:0005886(plasma membrane);GO:0005887(integral component of plasma membrane);GO:0007399(nervous system development);GO:0007267(cell-cell signaling);GO:0007267(cell-cell signaling)","NA","NA","NA","protocadherin alpha 9 [Source:HGNC Symbol;Acc:HGNC:8675]",{"v":0.0202037840198511,"d":"0.02"},{"v":0.0213894839702233,"d":"0.02"},{"v":0.944566219922704,"d":"0.94"},{"v":-0.0822761529002782,"d":"-0.08"},1,1,"down","no"]
["ENSG00000164078","MST1R","ENST00000411578;ENST00000468525;ENST00000497001;ENST00000296474","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0004713(protein tyrosine kinase activity);GO:0007169(transmembrane receptor protein tyrosine kinase signaling pathway);GO:0018108(peptidyl-tyrosine phosphorylation);GO:0005515(protein binding);GO:0004714(transmembrane receptor protein tyrosine kinase activity);GO:0002376(immune system process);GO:0045087(innate immune response);GO:0005886(plasma membrane);GO:0009615(response to virus);GO:0005887(integral component of plasma membrane);GO:0007338(single fertilization);GO:0007165(signal transduction);GO:0019899(enzyme binding);GO:0009986(cell surface);GO:0006928(movement of cell or subcellular component);GO:0006952(defense response);GO:0051897(positive regulation of protein kinase B signaling);GO:0008284(positive regulation of cell proliferation);GO:0043406(positive regulation of MAP kinase activity);GO:0048012(hepatocyte growth factor receptor signaling pathway);GO:0005011(macrophage colony-stimulating factor receptor activity);GO:0038145(macrophage colony-stimulating factor signaling pathway);GO:0001725(stress fiber);GO:0005773(vacuole);GO:0005773(vacuole)","NA","NA","NA","macrophage stimulating 1 receptor [Source:HGNC Symbol;Acc:HGNC:7381]",{"v":0.113148872810358,"d":"0.11"},{"v":0.0698339445925362,"d":"0.07"},{"v":1.62025607275307,"d":"1.62"},{"v":0.696221841317197,"d":"0.70"},1,1,"up","no"]
["ENSG00000258860","AL133163.2","ENST00000555024","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000145103","ILDR1","ENST00000344209;ENST00000273691","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0006898(receptor-mediated endocytosis);GO:0070506(high-density lipoprotein particle receptor activity);GO:0090277(positive regulation of peptide hormone secretion);GO:1990830(cellular response to leukemia inhibitory factor);GO:0061689(tricellular tight junction);GO:0061689(tricellular tight junction)","NA","NA","NA","immunoglobulin like domain containing receptor 1 [Source:HGNC Symbol;Acc:HGNC:28741]",{"v":0.22864068371148,"d":"0.23"},{"v":0.0454227074161869,"d":"0.05"},{"v":5.0336207751016,"d":"5.03"},{"v":2.3315965302675,"d":"2.33"},1,1,"up","no"]
["MSTRG.2672","AP000763.4","ENST00000544674","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000131686","CA6","ENST00000480186;ENST00000377436;ENST00000549778;ENST00000377443","GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0006730(one-carbon metabolic process);GO:0004089(carbonate dehydratase activity);GO:0005515(protein binding);GO:0016829(lyase activity);GO:0005576(extracellular region);GO:0005615(extracellular space);GO:0070062(extracellular exosome);GO:0015701(bicarbonate transport);GO:0001580(detection of chemical stimulus involved in sensory perception of bitter taste);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005829(cytosol)","00910(Nitrogen metabolism);00910(Nitrogen metabolism)","K01672","EC:4.2.1.1","carbonic anhydrase 6 [Source:HGNC Symbol;Acc:HGNC:1380]",{"v":0.306434576258452,"d":"0.31"},{"v":0.182374267092412,"d":"0.18"},{"v":1.6802511732819,"d":"1.68"},{"v":0.748676911196046,"d":"0.75"},1,1,"up","no"]
["ENSG00000130700","GATA5","ENST00000252997","GO:0005634(nucleus);GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0006355(regulation of transcription, DNA-templated);GO:0006366(transcription from RNA polymerase II promoter);GO:0045893(positive regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0043565(sequence-specific DNA binding);GO:0044212(transcription regulatory region DNA binding);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0003682(chromatin binding);GO:0005654(nucleoplasm);GO:0005667(transcription factor complex);GO:0000977(RNA polymerase II regulatory region sequence-specific DNA binding);GO:0001228(transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding);GO:0007596(blood coagulation);GO:0001085(RNA polymerase II transcription factor binding);GO:0060575(intestinal epithelial cell differentiation);GO:0001158(enhancer sequence-specific DNA binding);GO:0003705(transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding);GO:0071773(cellular response to BMP stimulus)","NA","NA","NA","GATA binding protein 5 [Source:HGNC Symbol;Acc:HGNC:15802]",{"v":0.019502,"d":"0.02"},0,"inf","inf",1,1,"up","no"]
["ENSG00000196169","KIF19","ENST00000359939;ENST00000551294;ENST00000551017;ENST00000547389;ENST00000389916;ENST00000549637","GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0003777(microtubule motor activity);GO:0008017(microtubule binding);GO:0005874(microtubule);GO:0003774(motor activity);GO:0007018(microtubule-based movement);GO:0005737(cytoplasm);GO:0005856(cytoskeleton);GO:0042995(cell projection);GO:0005929(cilium);GO:0016887(ATPase activity);GO:0005871(kinesin complex);GO:0008574(ATP-dependent microtubule motor activity, plus-end-directed);GO:0060404(axonemal microtubule depolymerization);GO:0070462(plus-end specific microtubule depolymerization);GO:0005930(axoneme);GO:0005930(axoneme)","NA","NA","NA","kinesin family member 19 [Source:HGNC Symbol;Acc:HGNC:26735]",{"v":0.193882903014184,"d":"0.19"},{"v":0.0519420007092199,"d":"0.05"},{"v":3.73268068936299,"d":"3.73"},{"v":1.90021209916448,"d":"1.90"},1,1,"up","no"]
["ENSG00000176219","OR11H6","ENST00000315519","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0004930(G-protein coupled receptor activity);GO:0007186(G-protein coupled receptor signaling pathway);GO:0005886(plasma membrane);GO:0004871(signal transducer activity);GO:0007165(signal transduction);GO:0004984(olfactory receptor activity);GO:0007608(sensory perception of smell);GO:0050896(response to stimulus);GO:0050911(detection of chemical stimulus involved in sensory perception of smell)","04740(Olfactory transduction)","K04257","NA","olfactory receptor family 11 subfamily H member 6 [Source:HGNC Symbol;Acc:HGNC:15349]",{"v":0.153913,"d":"0.15"},0,"inf","inf",1,1,"up","no"]
["ENSG00000064042","LIMCH1","ENST00000512228;ENST00000503057;ENST00000313860;ENST00000515847","GO:0046872(metal ion binding);GO:0003779(actin binding);GO:0031032(actomyosin structure organization);GO:0031032(actomyosin structure organization)","NA","NA","NA","LIM and calponin homology domains 1 [Source:HGNC Symbol;Acc:HGNC:29191]",{"v":0.0508088796722519,"d":"0.05"},{"v":0.0399404040692322,"d":"0.04"},{"v":1.2721173171954,"d":"1.27"},{"v":0.347231724970816,"d":"0.35"},1,1,"up","no"]
["ENSG00000128683","GAD1","ENST00000375272;ENST00000493875;ENST00000344257","GO:0003824(catalytic activity);GO:0016829(lyase activity);GO:0005515(protein binding);GO:0016831(carboxy-lyase activity);GO:0030170(pyridoxal phosphate binding);GO:0019752(carboxylic acid metabolic process);GO:0005886(plasma membrane);GO:0004351(glutamate decarboxylase activity);GO:0016595(glutamate binding);GO:0046982(protein heterodimerization activity);GO:0047485(protein N-terminus binding);GO:0009449(gamma-aminobutyric acid biosynthetic process);GO:0035176(social behavior);GO:0035641(locomotory exploration behavior);GO:0042493(response to drug);GO:0005737(cytoplasm);GO:0005739(mitochondrion);GO:0005938(cell cortex);GO:0030424(axon);GO:0043679(axon terminus);GO:0044306(neuron projection terminus);GO:0045202(synapse);GO:0048786(presynaptic active zone);GO:0060077(inhibitory synapse);GO:0005622(intracellular);GO:0007268(chemical synaptic transmission);GO:0007269(neurotransmitter secretion);GO:0006538(glutamate catabolic process);GO:0042136(neurotransmitter biosynthetic process);GO:0061202(clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane);GO:0012506(vesicle membrane);GO:0006540(glutamate decarboxylation to succinate);GO:0018352(protein-pyridoxal-5-phosphate linkage);GO:0018352(protein-pyridoxal-5-phosphate linkage)","00650(Butanoate metabolism);00250(Alanine, aspartate and glutamate metabolism);00410(beta-Alanine metabolism);00430(Taurine and hypotaurine metabolism);04727(GABAergic synapse);04940(Type I diabetes mellitus);04940(Type I diabetes mellitus)","K01580","EC:4.1.1.15","glutamate decarboxylase 1 [Source:HGNC Symbol;Acc:HGNC:4092]",{"v":0.025390719364232,"d":"0.03"},{"v":0.00204813346275176,"d":"0.00"},{"v":12.3970043095328,"d":"12.40"},{"v":3.6319196356672,"d":"3.63"},1,1,"up","no"]
["ENSG00000243438","LARP1BP2","ENST00000486594","NA","NA","NA","NA","La ribonucleoprotein domain family member 1B pseudogene 2 [Source:HGNC Symbol;Acc:HGNC:44084]",0,0,1,0,1,1,"no","no"]
["ENSG00000176402","GJC3","ENST00000312891","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005886(plasma membrane);GO:0005921(gap junction);GO:0030054(cell junction);GO:0007154(cell communication);GO:0005922(connexin complex);GO:0042803(protein homodimerization activity);GO:0007605(sensory perception of sound);GO:0042552(myelination);GO:0043209(myelin sheath)","NA","NA","NA","gap junction protein gamma 3 [Source:HGNC Symbol;Acc:HGNC:17495]",0,{"v":0.030773,"d":"0.03"},"-inf","-inf",1,1,"down","no"]
["ENSG00000137857","DUOX1","ENST00000321429;ENST00000561166;ENST00000558446;ENST00000558991","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0046872(metal ion binding);GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0005509(calcium ion binding);GO:0005886(plasma membrane);GO:0020037(heme binding);GO:0098869(cellular oxidant detoxification);GO:0004601(peroxidase activity);GO:0006979(response to oxidative stress);GO:0042446(hormone biosynthetic process);GO:0042744(hydrogen peroxide catabolic process);GO:0016324(apical plasma membrane);GO:0006590(thyroid hormone generation);GO:0019221(cytokine-mediated signaling pathway);GO:0016174(NAD(P)H oxidase activity);GO:0051591(response to cAMP);GO:0050661(NADP binding);GO:0050665(hydrogen peroxide biosynthetic process);GO:0042554(superoxide anion generation);GO:0042335(cuticle development);GO:0072593(reactive oxygen species metabolic process);GO:0072593(reactive oxygen species metabolic process)","NA","NA","NA","dual oxidase 1 [Source:HGNC Symbol;Acc:HGNC:3062]",{"v":0.147241774248634,"d":"0.15"},{"v":0.0712400735428051,"d":"0.07"},{"v":2.0668391668653,"d":"2.07"},{"v":1.04742612838912,"d":"1.05"},1,1,"up","no"]
["MSTRG.6372","AC004706.1","ENST00000576138","NA","NA","NA","NA",null,{"v":0.368995,"d":"0.37"},{"v":0.509068,"d":"0.51"},{"v":0.724844225132988,"d":"0.72"},{"v":-0.464257113242759,"d":"-0.46"},1,1,"down","no"]
["ENSG00000248962","AC025773.1","ENST00000513859","NA","NA","NA","NA",null,{"v":0.045364,"d":"0.05"},0,"inf","inf",1,1,"up","no"]
["MSTRG.6141","AC009163.7","ENST00000621929","NA","NA","NA","NA",null,{"v":0.156866,"d":"0.16"},{"v":0.142742,"d":"0.14"},{"v":1.09894775188802,"d":"1.10"},{"v":0.136122796765854,"d":"0.14"},1,1,"up","no"]
["ENSG00000227151","PRR20D","ENST00000452123","NA","NA","NA","NA","proline rich 20D [Source:HGNC Symbol;Acc:HGNC:37222]",0,{"v":0.001169,"d":"0.00"},"-inf","-inf",1,1,"down","no"]
["ENSG00000225872","LINC01529","ENST00000637365","NA","NA","NA","NA","long intergenic non-protein coding RNA 1529 [Source:HGNC Symbol;Acc:HGNC:51268]",{"v":0.0116425821064553,"d":"0.01"},0,"inf","inf",1,1,"up","no"]
["ENSG00000276517","AL133243.3","ENST00000617415","NA","NA","NA","NA",null,{"v":0.085556,"d":"0.09"},{"v":0.014276,"d":"0.01"},{"v":5.992995236761,"d":"5.99"},{"v":2.58327722725324,"d":"2.58"},1,1,"up","no"]
["ENSG00000228399","AL109741.2","ENST00000455561","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["MSTRG.4585","AL136040.2","ENST00000618431","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000277406","AC243756.2","ENST00000618406","NA","NA","NA","NA",null,{"v":0.925484,"d":"0.93"},{"v":0.512192,"d":"0.51"},{"v":1.80690834686992,"d":"1.81"},{"v":0.853523329185511,"d":"0.85"},1,1,"up","no"]
["ENSG00000179057","IGSF22","ENST00000510673;ENST00000513874","GO:0008307(structural constituent of muscle);GO:0051015(actin filament binding);GO:0051371(muscle alpha-actinin binding);GO:0097493(structural molecule activity conferring elasticity);GO:0006941(striated muscle contraction);GO:0007015(actin filament organization);GO:0045214(sarcomere organization);GO:0071688(striated muscle myosin thick filament assembly);GO:0005859(muscle myosin complex);GO:0030018(Z disc);GO:0031430(M band);GO:0031430(M band)","NA","NA","NA","immunoglobulin superfamily member 22 [Source:HGNC Symbol;Acc:HGNC:26750]",{"v":0.0608565071266267,"d":"0.06"},{"v":0.0386117512910556,"d":"0.04"},{"v":1.57611362064077,"d":"1.58"},{"v":0.656371541156233,"d":"0.66"},1,1,"up","no"]
["ENSG00000162399","BSND","ENST00000371265","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:1903959(regulation of anion transmembrane transport);GO:0005886(plasma membrane);GO:0065009(regulation of molecular function);GO:0005254(chloride channel activity);GO:1902476(chloride transmembrane transport);GO:0006821(chloride transport);GO:0005887(integral component of plasma membrane);GO:0034220(ion transmembrane transport);GO:0016323(basolateral plasma membrane);GO:0043234(protein complex);GO:0005247(voltage-gated chloride channel activity);GO:0017081(chloride channel regulator activity)","NA","NA","NA","barttin CLCNK type accessory beta subunit [Source:HGNC Symbol;Acc:HGNC:16512]",{"v":0.026254,"d":"0.03"},0,"inf","inf",1,1,"up","no"]
["ENSG00000280184","AL023806.3","ENST00000638502;ENST00000625058","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000257513","NPIPB1P","ENST00000547442","NA","NA","NA","NA","nuclear pore complex interacting protein family member B1, pseudogene [Source:HGNC Symbol;Acc:HGNC:37452]",0,{"v":0.0347409143865843,"d":"0.03"},"-inf","-inf",1,1,"down","no"]
["ENSG00000100122","CRYBB1","ENST00000215939","GO:0007601(visual perception);GO:0005515(protein binding);GO:0005212(structural constituent of eye lens)","NA","NA","NA","crystallin beta B1 [Source:HGNC Symbol;Acc:HGNC:2397]",{"v":0.090011,"d":"0.09"},{"v":0.062515,"d":"0.06"},{"v":1.43983044069423,"d":"1.44"},{"v":0.525898925019824,"d":"0.53"},1,1,"up","no"]
["MSTRG.3960","RLIMP1","ENST00000339626","NA","NA","NA","NA","ring finger protein, LIM domain interacting pseudogene 1 [Source:HGNC Symbol;Acc:HGNC:39682]",0,0,1,0,1,1,"no","no"]
["ENSG00000227467","LINC01537","ENST00000450804","NA","NA","NA","NA","long intergenic non-protein coding RNA 1537 [Source:HGNC Symbol;Acc:HGNC:51301]",{"v":0.081264,"d":"0.08"},{"v":0.037244,"d":"0.04"},{"v":2.18193534529052,"d":"2.18"},{"v":1.12560835261903,"d":"1.13"},1,1,"up","no"]
["ENSG00000167377","ZNF23","ENST00000357254;ENST00000393539;ENST00000539742;ENST00000358700;ENST00000497160;ENST00000564588;ENST00000576258;ENST00000564528","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0005622(intracellular);GO:0005515(protein binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding)","NA","NA","NA","zinc finger protein 23 [Source:HGNC Symbol;Acc:HGNC:13023]",{"v":0.614694918622204,"d":"0.61"},{"v":0.0675458354604089,"d":"0.07"},{"v":9.10041180825277,"d":"9.10"},{"v":3.18593183105656,"d":"3.19"},1,1,"up","no"]
["ENSG00000106853","PTGR1","ENST00000407693;ENST00000374313;ENST00000538962;ENST00000374308","GO:0005737(cytoplasm);GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0070062(extracellular exosome);GO:0006691(leukotriene metabolic process);GO:0032440(2-alkenal reductase [NAD(P)] activity);GO:0036132(13-prostaglandin reductase activity);GO:0047522(15-oxoprostaglandin 13-oxidase activity);GO:0006693(prostaglandin metabolic process);GO:0097327(response to antineoplastic agent);GO:0097327(response to antineoplastic agent)","NA","NA","NA","prostaglandin reductase 1 [Source:HGNC Symbol;Acc:HGNC:18429]",{"v":0.0931277165502418,"d":"0.09"},{"v":0.0491969032778076,"d":"0.05"},{"v":1.89295891296986,"d":"1.89"},{"v":0.920643097413552,"d":"0.92"},1,1,"up","no"]
["ENSG00000248356","AC093864.1","ENST00000504555","NA","NA","NA","NA",null,{"v":0.010507,"d":"0.01"},0,"inf","inf",1,1,"up","no"]
["ENSG00000085831","TTC39A","ENST00000527205;ENST00000525906;ENST00000262676;ENST00000447632","GO:0003674(molecular_function);GO:0008150(biological_process);GO:0005575(cellular_component);GO:0005575(cellular_component)","NA","NA","NA","tetratricopeptide repeat domain 39A [Source:HGNC Symbol;Acc:HGNC:18657]",{"v":0.0700779077120273,"d":"0.07"},{"v":0.0478664509720145,"d":"0.05"},{"v":1.4640297387621,"d":"1.46"},{"v":0.54994485931106,"d":"0.55"},1,1,"up","no"]
["ENSG00000183571","PGPEP1L","ENST00000535714","GO:0016787(hydrolase activity);GO:0008233(peptidase activity);GO:0008234(cysteine-type peptidase activity);GO:0006508(proteolysis);GO:0005829(cytosol);GO:0016920(pyroglutamyl-peptidase activity)","NA","NA","NA","pyroglutamyl-peptidase I-like [Source:HGNC Symbol;Acc:HGNC:27080]",{"v":0.053799489257213,"d":"0.05"},0,"inf","inf",1,1,"up","no"]
["MSTRG.13759","AC007000.1","ENST00000453064","NA","NA","NA","NA",null,{"v":0.581564,"d":"0.58"},0,"inf","inf",1,1,"up","no"]
["ENSG00000187686","KRT18P59","ENST00000524879","NA","NA","NA","NA","keratin 18 pseudogene 59 [Source:HGNC Symbol;Acc:HGNC:48886]",{"v":0.0307982333732774,"d":"0.03"},0,"inf","inf",1,1,"up","no"]
["ENSG00000250596","AC096751.1","ENST00000515178","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000174640","SLCO2A1","ENST00000310926","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005215(transporter activity);GO:0005886(plasma membrane);GO:0015347(sodium-independent organic anion transmembrane transporter activity);GO:0043252(sodium-independent organic anion transport);GO:0005887(integral component of plasma membrane);GO:0005319(lipid transporter activity);GO:0006869(lipid transport);GO:0015132(prostaglandin transmembrane transporter activity);GO:0015732(prostaglandin transport);GO:0006811(ion transport)","NA","NA","NA","solute carrier organic anion transporter family member 2A1 [Source:HGNC Symbol;Acc:HGNC:10955]",{"v":0.0827022152186258,"d":"0.08"},{"v":0.0498007047132311,"d":"0.05"},{"v":1.66066355275196,"d":"1.66"},{"v":0.73175981565877,"d":"0.73"},1,1,"up","no"]
["ENSG00000131941","RHPN2","ENST00000588683;ENST00000591502;ENST00000592247;ENST00000544458;ENST00000585641","GO:0005737(cytoplasm);GO:0007165(signal transduction);GO:0048471(perinuclear region of cytoplasm);GO:0005829(cytosol);GO:0005829(cytosol)","NA","NA","NA","rhophilin Rho GTPase binding protein 2 [Source:HGNC Symbol;Acc:HGNC:19974]",{"v":0.0605084556619484,"d":"0.06"},{"v":0.0419025110324729,"d":"0.04"},{"v":1.44402934743115,"d":"1.44"},{"v":0.530100062836678,"d":"0.53"},1,1,"up","no"]
["ENSG00000235670","RPL21P40","ENST00000428586","NA","NA","NA","NA","ribosomal protein L21 pseudogene 40 [Source:HGNC Symbol;Acc:HGNC:36189]",0,0,1,0,1,1,"no","no"]
["MSTRG.774","ALX3","ENST00000369792","GO:0005634(nucleus);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0043565(sequence-specific DNA binding);GO:0007275(multicellular organism development);GO:0048701(embryonic cranial skeleton morphogenesis);GO:0007389(pattern specification process);GO:0035115(embryonic forelimb morphogenesis);GO:0035116(embryonic hindlimb morphogenesis);GO:0042981(regulation of apoptotic process);GO:0048704(embryonic skeletal system morphogenesis)","NA","NA","NA","ALX homeobox 3 [Source:HGNC Symbol;Acc:HGNC:449]",{"v":0.03048,"d":"0.03"},0,"inf","inf",1,1,"up","no"]
["ENSG00000266153","AP005380.1","ENST00000584896","NA","NA","NA","NA",null,{"v":0.006265,"d":"0.01"},0,"inf","inf",1,1,"up","no"]
["ENSG00000256612","CYP2B7P","ENST00000593298;ENST00000599198","NA","NA","NA","NA","cytochrome P450 family 2 subfamily B member 7, pseudogene [Source:HGNC Symbol;Acc:HGNC:2616]",{"v":0.0500796151574803,"d":"0.05"},{"v":0.0284500452755906,"d":"0.03"},{"v":1.76026486679961,"d":"1.76"},{"v":0.815792527310258,"d":"0.82"},1,1,"up","no"]
["ENSG00000100373","UPK3A","ENST00000216211;ENST00000396082","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005515(protein binding);GO:0070062(extracellular exosome);GO:0030855(epithelial cell differentiation);GO:0000902(cell morphogenesis);GO:0001822(kidney development);GO:0006833(water transport);GO:0015840(urea transport);GO:0055075(potassium ion homeostasis);GO:0055078(sodium ion homeostasis);GO:0060157(urinary bladder development);GO:0016324(apical plasma membrane);GO:0016324(apical plasma membrane)","05219(Bladder cancer);05219(Bladder cancer)","K19520","NA","uroplakin 3A [Source:HGNC Symbol;Acc:HGNC:12580]",{"v":0.754646306374881,"d":"0.75"},{"v":0.230507025689819,"d":"0.23"},{"v":3.27385381906046,"d":"3.27"},{"v":1.71098990543308,"d":"1.71"},1,1,"up","no"]
["ENSG00000154330","PGM5","ENST00000396392;ENST00000496758;ENST00000396396","GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0000287(magnesium ion binding);GO:0007155(cell adhesion);GO:0005975(carbohydrate metabolic process);GO:0005856(cytoskeleton);GO:0030054(cell junction);GO:0016868(intramolecular transferase activity, phosphotransferases);GO:0005925(focal adhesion);GO:0071704(organic substance metabolic process);GO:0042383(sarcolemma);GO:0030018(Z disc);GO:0001725(stress fiber);GO:0005912(adherens junction);GO:0014704(intercalated disc);GO:0009898(cytoplasmic side of plasma membrane);GO:0043034(costamere);GO:0005198(structural molecule activity);GO:0016010(dystrophin-associated glycoprotein complex);GO:0005913(cell-cell adherens junction);GO:0005914(spot adherens junction);GO:0030055(cell-substrate junction);GO:0030055(cell-substrate junction)","NA","NA","NA","phosphoglucomutase 5 [Source:HGNC Symbol;Acc:HGNC:8908]",{"v":0.0431238235927821,"d":"0.04"},{"v":0.107790070293563,"d":"0.11"},{"v":0.400072320904288,"d":"0.40"},{"v":-1.32166727594006,"d":"-1.32"},1,1,"down","no"]
["ENSG00000236800","AC068898.1","ENST00000440750","NA","NA","NA","NA",null,{"v":0.012275,"d":"0.01"},{"v":0.132234,"d":"0.13"},{"v":0.0928278657531346,"d":"0.09"},{"v":-3.42929824057252,"d":"-3.43"},1,1,"down","no"]
["ENSG00000113205","PCDHB3","ENST00000231130","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005509(calcium ion binding);GO:0007155(cell adhesion);GO:0007156(homophilic cell adhesion via plasma membrane adhesion molecules);GO:0005886(plasma membrane);GO:0005887(integral component of plasma membrane);GO:0007268(chemical synaptic transmission);GO:0007399(nervous system development);GO:0007416(synapse assembly);GO:0016339(calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules)","NA","NA","NA","protocadherin beta 3 [Source:HGNC Symbol;Acc:HGNC:8688]",{"v":0.02768,"d":"0.03"},{"v":0.067269,"d":"0.07"},{"v":0.41148225780077,"d":"0.41"},{"v":-1.28109786869895,"d":"-1.28"},1,1,"down","no"]
["ENSG00000261914","RPL23AP84","ENST00000571193","NA","NA","NA","NA","ribosomal protein L23a pseudogene 84 [Source:HGNC Symbol;Acc:HGNC:51575]",0,0,1,0,1,1,"no","no"]
["ENSG00000106927","AMBP","ENST00000540645;ENST00000603230;ENST00000265132","GO:0007155(cell adhesion);GO:0004867(serine-type endopeptidase inhibitor activity);GO:0010951(negative regulation of endopeptidase activity);GO:0042803(protein homodimerization activity);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0005615(extracellular space);GO:0036094(small molecule binding);GO:0006898(receptor-mediated endocytosis);GO:0030414(peptidase inhibitor activity);GO:0010466(negative regulation of peptidase activity);GO:0020037(heme binding);GO:0018298(protein-chromophore linkage);GO:0042167(heme catabolic process);GO:0070062(extracellular exosome);GO:0072562(blood microparticle);GO:0016032(viral process);GO:0007565(female pregnancy);GO:0046329(negative regulation of JNK cascade);GO:0019862(IgA binding);GO:0050777(negative regulation of immune response);GO:0019855(calcium channel inhibitor activity);GO:0046904(calcium oxalate binding);GO:0030163(protein catabolic process);GO:0009986(cell surface);GO:0043231(intracellular membrane-bounded organelle);GO:0043231(intracellular membrane-bounded organelle)","NA","NA","NA","alpha-1-microglobulin/bikunin precursor [Source:HGNC Symbol;Acc:HGNC:453]",{"v":0.038231882410583,"d":"0.04"},{"v":0.0154526046055855,"d":"0.02"},{"v":2.47413839843956,"d":"2.47"},{"v":1.30692620409675,"d":"1.31"},1,1,"up","no"]
["ENSG00000224424","PRKAR2A-AS1","ENST00000431705;ENST00000412171;ENST00000435419;ENST00000416209","NA","NA","NA","NA","PRKAR2A antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:40471]",{"v":0.341752984426857,"d":"0.34"},{"v":0.13841328618841,"d":"0.14"},{"v":2.46907644372852,"d":"2.47"},{"v":1.30397150366611,"d":"1.30"},1,1,"up","no"]
["ENSG00000114487","MORC1","ENST00000232603","GO:0005634(nucleus);GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0007275(multicellular organism development);GO:0030154(cell differentiation);GO:0007283(spermatogenesis);GO:0010529(negative regulation of transposition);GO:0040029(regulation of gene expression, epigenetic);GO:0043046(DNA methylation involved in gamete generation);GO:0044026(DNA hypermethylation);GO:2000143(negative regulation of DNA-templated transcription, initiation)","NA","NA","NA","MORC family CW-type zinc finger 1 [Source:HGNC Symbol;Acc:HGNC:7198]",{"v":0.020267,"d":"0.02"},{"v":0.036514,"d":"0.04"},{"v":0.555047379087473,"d":"0.56"},{"v":-0.849317169087482,"d":"-0.85"},1,1,"down","no"]
["ENSG00000187566","NHLRC1","ENST00000340650","GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0016740(transferase activity);GO:0016567(protein ubiquitination);GO:0005783(endoplasmic reticulum);GO:0005515(protein binding);GO:0006914(autophagy);GO:0005829(cytosol);GO:0004842(ubiquitin-protein transferase activity);GO:0043161(proteasome-mediated ubiquitin-dependent protein catabolic process);GO:0005978(glycogen biosynthetic process);GO:0000209(protein polyubiquitination);GO:0061630(ubiquitin protein ligase activity);GO:0031398(positive regulation of protein ubiquitination);GO:0048471(perinuclear region of cytoplasm)","04120(Ubiquitin mediated proteolysis)","K10602","EC:2.3.2.27","NHL repeat containing E3 ubiquitin protein ligase 1 [Source:HGNC Symbol;Acc:HGNC:21576]",{"v":0.317528,"d":"0.32"},{"v":0.238876,"d":"0.24"},{"v":1.32925869488772,"d":"1.33"},{"v":0.410621903344112,"d":"0.41"},1,1,"up","no"]
["ENSG00000197880","MDS2","ENST00000612756;ENST00000477916;ENST00000374555","GO:0005615(extracellular space);GO:0005615(extracellular space)","NA","NA","NA","myelodysplastic syndrome 2 translocation associated [Source:HGNC Symbol;Acc:HGNC:29633]",{"v":0.358284072362278,"d":"0.36"},{"v":0.119369031279178,"d":"0.12"},{"v":3.00148261674613,"d":"3.00"},{"v":1.58567531254026,"d":"1.59"},1,1,"up","no"]
["ENSG00000106511","MEOX2","ENST00000262041","GO:0090051(negative regulation of cell migration involved in sprouting angiogenesis);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016607(nuclear speck);GO:0006355(regulation of transcription, DNA-templated);GO:0006366(transcription from RNA polymerase II promoter);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0043565(sequence-specific DNA binding);GO:0005515(protein binding);GO:0007275(multicellular organism development);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0001077(transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0008015(blood circulation);GO:0000980(RNA polymerase II distal enhancer sequence-specific DNA binding);GO:0001205(transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding);GO:0061053(somite development);GO:0001525(angiogenesis);GO:0001757(somite specification);GO:0007519(skeletal muscle tissue development);GO:0060021(palate development);GO:0060173(limb development);GO:0070997(neuron death)","NA","NA","NA","mesenchyme homeobox 2 [Source:HGNC Symbol;Acc:HGNC:7014]",0,{"v":0.017033,"d":"0.02"},"-inf","-inf",1,1,"down","no"]
["ENSG00000186564","FOXD2","ENST00000334793","GO:0005634(nucleus);GO:0006355(regulation of transcription, DNA-templated);GO:0006366(transcription from RNA polymerase II promoter);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0043565(sequence-specific DNA binding);GO:0000981(RNA polymerase II transcription factor activity, sequence-specific DNA binding);GO:0001228(transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0009653(anatomical structure morphogenesis);GO:0030154(cell differentiation)","NA","NA","NA","forkhead box D2 [Source:HGNC Symbol;Acc:HGNC:3803]",{"v":0.1197,"d":"0.12"},{"v":0.076349,"d":"0.08"},{"v":1.56780049509489,"d":"1.57"},{"v":0.648741986079707,"d":"0.65"},1,1,"up","no"]
["MSTRG.14179","AC016065.1","ENST00000606853;ENST00000500118","NA","NA","NA","NA",null,{"v":0.0923857065439673,"d":"0.09"},{"v":0.254502375255624,"d":"0.25"},{"v":0.363005282175361,"d":"0.36"},{"v":-1.46193755351826,"d":"-1.46"},1,1,"down","no"]
["ENSG00000230772","VN1R108P","ENST00000431580","NA","NA","NA","NA","vomeronasal 1 receptor 108 pseudogene [Source:HGNC Symbol;Acc:HGNC:37432]",{"v":0.06193,"d":"0.06"},0,"inf","inf",1,1,"up","no"]
["MSTRG.11808","AC106864.1","ENST00000509938;ENST00000510655","NA","NA","NA","NA",null,{"v":0.166306199740597,"d":"0.17"},{"v":0.216881141374838,"d":"0.22"},{"v":0.766808025291458,"d":"0.77"},{"v":-0.383062658784271,"d":"-0.38"},1,1,"down","no"]
["ENSG00000261448","AC109446.3","ENST00000567344","NA","NA","NA","NA",null,{"v":0.23042,"d":"0.23"},{"v":0.142352,"d":"0.14"},{"v":1.61866359447005,"d":"1.62"},{"v":0.694803182663809,"d":"0.69"},1,1,"up","no"]
["MSTRG.2619","C11orf72","ENST00000333139","NA","NA","NA","NA","chromosome 11 open reading frame 72 [Source:HGNC Symbol;Acc:HGNC:26915]",{"v":0.084262015612161,"d":"0.08"},0,"inf","inf",1,1,"up","no"]
["MSTRG.830","LINC01762","ENST00000443219;ENST00000430107;ENST00000434879","NA","NA","NA","NA","long intergenic non-protein coding RNA 1762 [Source:HGNC Symbol;Acc:HGNC:52552]",{"v":0.0552705291005291,"d":"0.06"},{"v":0.0299511111111111,"d":"0.03"},{"v":1.84535822045096,"d":"1.85"},{"v":0.883900899052115,"d":"0.88"},1,1,"up","no"]
["ENSG00000272800","AC021851.1","ENST00000608537","NA","NA","NA","NA",null,{"v":0.237216,"d":"0.24"},{"v":0.113146,"d":"0.11"},{"v":2.09654782316653,"d":"2.10"},{"v":1.06801573906019,"d":"1.07"},1,1,"up","no"]
["ENSG00000130203","APOE","ENST00000252486;ENST00000434152","GO:0005615(extracellular space);GO:0050728(negative regulation of inflammatory response);GO:0001937(negative regulation of endothelial cell proliferation);GO:0005737(cytoplasm);GO:0042632(cholesterol homeostasis);GO:0043537(negative regulation of blood vessel endothelial cell migration);GO:0005623(cell);GO:0006810(transport);GO:0005634(nucleus);GO:0016020(membrane);GO:0005576(extracellular region);GO:0006629(lipid metabolic process);GO:0008202(steroid metabolic process);GO:0042157(lipoprotein metabolic process);GO:0006869(lipid transport);GO:0043085(positive regulation of catalytic activity);GO:0005515(protein binding);GO:0008289(lipid binding);GO:0005783(endoplasmic reticulum);GO:0098869(cellular oxidant detoxification);GO:0008203(cholesterol metabolic process);GO:0006898(receptor-mediated endocytosis);GO:0005886(plasma membrane);GO:0017127(cholesterol transporter activity);GO:0060228(phosphatidylcholine-sterol O-acyltransferase activator activity);GO:0071813(lipoprotein particle binding);GO:0002021(response to dietary excess);GO:0006707(cholesterol catabolic process);GO:0006874(cellular calcium ion homeostasis);GO:0006979(response to oxidative stress);GO:0010468(regulation of gene expression);GO:0010873(positive regulation of cholesterol esterification);GO:0010877(lipid transport involved in lipid storage);GO:0010976(positive regulation of neuron projection development);GO:0033344(cholesterol efflux);GO:0034372(very-low-density lipoprotein particle remodeling);GO:0034374(low-density lipoprotein particle remodeling);GO:0042158(lipoprotein biosynthetic process);GO:0042159(lipoprotein catabolic process);GO:0042311(vasodilation);GO:0048844(artery morphogenesis);GO:0051651(maintenance of location in cell);GO:0055088(lipid homeostasis);GO:0070328(triglyceride homeostasis);GO:0072358(cardiovascular system development);GO:0090209(negative regulation of triglyceride metabolic process);GO:0097006(regulation of plasma lipoprotein particle levels);GO:0034362(low-density lipoprotein particle);GO:0008201(heparin binding);GO:0034361(very-low-density lipoprotein particle);GO:0042627(chylomicron);GO:0070062(extracellular exosome);GO:0044267(cellular protein metabolic process);GO:0031012(extracellular matrix);GO:0001540(amyloid-beta binding);GO:0072562(blood microparticle);GO:0043687(post-translational protein modification);GO:0007010(cytoskeleton organization);GO:0034364(high-density lipoprotein particle);GO:0042803(protein homodimerization activity);GO:0005788(endoplasmic reticulum lumen);GO:0106003(amyloid-beta complex);GO:0001523(retinoid metabolic process);GO:1903561(extracellular vesicle);GO:0042802(identical protein binding);GO:0051000(positive regulation of nitric-oxide synthase activity);GO:0090090(negative regulation of canonical Wnt signaling pathway);GO:0043524(negative regulation of neuron apoptotic process);GO:0030669(clathrin-coated endocytic vesicle membrane);GO:0051044(positive regulation of membrane protein ectodomain proteolysis);GO:0042982(amyloid precursor protein metabolic process);GO:0030425(dendrite);GO:0043025(neuronal cell body);GO:0015485(cholesterol binding);GO:0046907(intracellular transport);GO:0005319(lipid transporter activity);GO:0005543(phospholipid binding);GO:0016209(antioxidant activity);GO:0034375(high-density lipoprotein particle remodeling);GO:0034380(high-density lipoprotein particle assembly);GO:0034384(high-density lipoprotein particle clearance);GO:0043691(reverse cholesterol transport);GO:0007186(G-protein coupled receptor signaling pathway);GO:0010875(positive regulation of cholesterol efflux);GO:0032489(regulation of Cdc42 protein signal transduction);GO:0033700(phospholipid efflux);GO:0050750(low-density lipoprotein particle receptor binding);GO:0030516(regulation of axon extension);GO:1900272(negative regulation of long-term synaptic potentiation);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0010544(negative regulation of platelet activation);GO:0071682(endocytic vesicle lumen);GO:0007263(nitric oxide mediated signal transduction);GO:0007616(long-term memory);GO:0034382(chylomicron remnant clearance);GO:0045807(positive regulation of endocytosis);GO:0051246(regulation of protein metabolic process);GO:0061771(response to caloric restriction);GO:0043407(negative regulation of MAP kinase activity);GO:0005769(early endosome);GO:0019433(triglyceride catabolic process);GO:0031102(neuron projection regeneration);GO:0034371(chylomicron remodeling);GO:0034378(chylomicron assembly);GO:0005198(structural molecule activity);GO:0046911(metal chelating activity);GO:0046983(protein dimerization activity);GO:0048156(tau protein binding);GO:0070326(very-low-density lipoprotein particle receptor binding);GO:0000302(response to reactive oxygen species);GO:0006641(triglyceride metabolic process);GO:0007271(synaptic transmission, cholinergic);GO:0010977(negative regulation of neuron projection development);GO:0015909(long-chain fatty acid transport);GO:0017038(protein import);GO:0019068(virion assembly);GO:0019934(cGMP-mediated signaling);GO:0030195(negative regulation of blood coagulation);GO:0030828(positive regulation of cGMP biosynthetic process);GO:0032269(negative regulation of cellular protein metabolic process);GO:0032462(regulation of protein homooligomerization);GO:0032805(positive regulation of low-density lipoprotein particle receptor catabolic process);GO:0034447(very-low-density lipoprotein particle clearance);GO:0035641(locomotory exploration behavior);GO:0044794(positive regulation by host of viral process);GO:0045541(negative regulation of cholesterol biosynthetic process);GO:0046889(positive regulation of lipid biosynthetic process);GO:0048168(regulation of neuronal synaptic plasticity);GO:0055089(fatty acid homeostasis);GO:0060999(positive regulation of dendritic spine development);GO:0090181(regulation of cholesterol metabolic process);GO:0097113(AMPA glutamate receptor clustering);GO:0097114(NMDA glutamate receptor clustering);GO:1900221(regulation of amyloid-beta clearance);GO:1901215(negative regulation of neuron death);GO:1901628(positive regulation of postsynaptic membrane organization);GO:1901630(negative regulation of presynaptic membrane organization);GO:1902430(negative regulation of amyloid-beta formation);GO:1902952(positive regulation of dendritic spine maintenance);GO:1902995(positive regulation of phospholipid efflux);GO:1903002(positive regulation of lipid transport across blood brain barrier);GO:1905855(positive regulation of heparan sulfate binding);GO:1905860(positive regulation of heparan sulfate proteoglycan binding);GO:1905890(regulation of cellular response to very-low-density lipoprotein particle stimulus);GO:1905906(regulation of amyloid fibril formation);GO:1905908(positive regulation of amyloid fibril formation);GO:2000822(regulation of behavioral fear response);GO:0005794(Golgi apparatus);GO:0034363(intermediate-density lipoprotein particle);GO:0034365(discoidal high-density lipoprotein particle);GO:1990777(lipoprotein particle);GO:1990777(lipoprotein particle)","04979(Cholesterol metabolism);05010(Alzheimer's disease);05010(Alzheimer's disease)","K04524","NA","apolipoprotein E [Source:HGNC Symbol;Acc:HGNC:613]",{"v":0.0202099497946143,"d":"0.02"},{"v":0.0208232514833409,"d":"0.02"},{"v":0.970547265914871,"d":"0.97"},{"v":-0.0431296205980699,"d":"-0.04"},1,1,"down","no"]
["ENSG00000283809","AC007326.4","ENST00000638240","NA","NA","NA","NA",null,{"v":0.344317,"d":"0.34"},{"v":0.196549,"d":"0.20"},{"v":1.75181252512096,"d":"1.75"},{"v":0.808848389351046,"d":"0.81"},1,1,"up","no"]
["MSTRG.2057","AL360181.1","ENST00000452591","NA","NA","NA","NA",null,{"v":0.173203,"d":"0.17"},0,"inf","inf",1,1,"up","no"]
["ENSG00000166359","WDR88","ENST00000592765;ENST00000361680","NA","NA","NA","NA","WD repeat domain 88 [Source:HGNC Symbol;Acc:HGNC:26999]",{"v":0.13561856056491,"d":"0.14"},{"v":0.165016436719174,"d":"0.17"},{"v":0.821848800405905,"d":"0.82"},{"v":-0.283055096319863,"d":"-0.28"},1,1,"down","no"]
["ENSG00000273387","AC005005.3","ENST00000609017","NA","NA","NA","NA",null,{"v":0.032567,"d":"0.03"},{"v":0.097072,"d":"0.10"},{"v":0.335493242129553,"d":"0.34"},{"v":-1.57564438850474,"d":"-1.58"},1,1,"down","no"]
["ENSG00000198342","ZNF442","ENST00000438182;ENST00000242804;ENST00000462995","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0005622(intracellular);GO:0005622(intracellular)","NA","NA","NA","zinc finger protein 442 [Source:HGNC Symbol;Acc:HGNC:20877]",{"v":0.044932251332014,"d":"0.04"},{"v":0.00625071669964987,"d":"0.01"},{"v":7.18833591266916,"d":"7.19"},{"v":2.84565782790999,"d":"2.85"},1,1,"up","no"]
["ENSG00000255804","OR6J1","ENST00000540461","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0004930(G-protein coupled receptor activity);GO:0007186(G-protein coupled receptor signaling pathway);GO:0005886(plasma membrane);GO:0004871(signal transducer activity);GO:0007165(signal transduction);GO:0004984(olfactory receptor activity);GO:0007608(sensory perception of smell);GO:0050896(response to stimulus);GO:0050911(detection of chemical stimulus involved in sensory perception of smell)","NA","NA","NA","olfactory receptor family 6 subfamily J member 1 (gene/pseudogene) [Source:HGNC Symbol;Acc:HGNC:14707]",{"v":0.009338,"d":"0.01"},0,"inf","inf",1,1,"up","no"]
["MSTRG.8162","CYP2T1P","ENST00000432607;ENST00000641596","NA","NA","NA","NA","cytochrome P450 family 2 subfamily T member 1, pseudogene [Source:HGNC Symbol;Acc:HGNC:18852]",{"v":0.603437112676056,"d":"0.60"},{"v":0.201266719792439,"d":"0.20"},{"v":2.9981961910959,"d":"3.00"},{"v":1.58409479111107,"d":"1.58"},1,1,"up","no"]
["MSTRG.2556","MIR4489","ENST00000578869","NA","NA","NA","NA","microRNA 4489 [Source:HGNC Symbol;Acc:HGNC:41685]",0,{"v":0.104799,"d":"0.10"},"-inf","-inf",1,1,"down","no"]
["MSTRG.12235","CAST","ENST00000509602","GO:0003723(RNA binding);GO:0005783(endoplasmic reticulum);GO:0005829(cytosol);GO:0005515(protein binding);GO:0004869(cysteine-type endopeptidase inhibitor activity);GO:0030414(peptidase inhibitor activity);GO:0010466(negative regulation of peptidase activity);GO:0045296(cadherin binding);GO:0004866(endopeptidase inhibitor activity);GO:0016020(membrane);GO:2000675(negative regulation of type B pancreatic cell apoptotic process);GO:0010859(calcium-dependent cysteine-type endopeptidase inhibitor activity);GO:0097340(inhibition of cysteine-type endopeptidase activity)","NA","NA","NA","calpastatin [Source:HGNC Symbol;Acc:HGNC:1515]",0,{"v":0.022389,"d":"0.02"},"-inf","-inf",1,1,"down","no"]
["MSTRG.4904","AC013356.2","ENST00000559730","NA","NA","NA","NA",null,0,{"v":0.085545,"d":"0.09"},"-inf","-inf",1,1,"down","no"]
["ENSG00000232457","SLC16A6P1","ENST00000413214","NA","NA","NA","NA","SLC16A6 pseudogene 1 [Source:HGNC Symbol;Acc:HGNC:48932]",{"v":0.360849,"d":"0.36"},{"v":3.6e-05,"d":"0.00"},{"v":10023.5833333333,"d":"10023.58"},{"v":13.2911107297062,"d":"13.29"},1,1,"up","no"]
["MSTRG.6535","AC015688.8","ENST00000577746","NA","NA","NA","NA",null,{"v":0.014166,"d":"0.01"},0,"inf","inf",1,1,"up","no"]
["MSTRG.6733","AC015849.3","ENST00000603981","NA","NA","NA","NA",null,{"v":0.694906,"d":"0.69"},{"v":0.455772,"d":"0.46"},{"v":1.52467900616975,"d":"1.52"},{"v":0.608505541067696,"d":"0.61"},1,1,"up","no"]
["ENSG00000142619","PADI3","ENST00000375460","GO:0005737(cytoplasm);GO:0016787(hydrolase activity);GO:0005509(calcium ion binding);GO:0004668(protein-arginine deiminase activity);GO:0018101(protein citrullination);GO:0005634(nucleus);GO:0042802(identical protein binding);GO:0005829(cytosol);GO:0006325(chromatin organization);GO:0036414(histone citrullination)","NA","NA","NA","peptidyl arginine deiminase 3 [Source:HGNC Symbol;Acc:HGNC:18337]",{"v":0.05051,"d":"0.05"},{"v":0.047607,"d":"0.05"},{"v":1.06097842754217,"d":"1.06"},{"v":0.085395322799019,"d":"0.09"},1,1,"up","no"]
["ENSG00000261839","AL358933.1","ENST00000565046","NA","NA","NA","NA",null,0,{"v":0.016121,"d":"0.02"},"-inf","-inf",1,1,"down","no"]
["ENSG00000171505","OR1N1","ENST00000304880;ENST00000619659","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0004930(G-protein coupled receptor activity);GO:0007186(G-protein coupled receptor signaling pathway);GO:0005886(plasma membrane);GO:0004871(signal transducer activity);GO:0007165(signal transduction);GO:0004984(olfactory receptor activity);GO:0007608(sensory perception of smell);GO:0050896(response to stimulus);GO:0050911(detection of chemical stimulus involved in sensory perception of smell);GO:0004888(transmembrane signaling receptor activity);GO:0050907(detection of chemical stimulus involved in sensory perception);GO:0050907(detection of chemical stimulus involved in sensory perception)","04740(Olfactory transduction);04740(Olfactory transduction)","K04257","NA","olfactory receptor family 1 subfamily N member 1 [Source:HGNC Symbol;Acc:HGNC:8221]",{"v":0.109482546325879,"d":"0.11"},0,"inf","inf",1,1,"up","no"]
["ENSG00000186185","KIF18B","ENST00000587309","GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0005634(nucleus);GO:0005829(cytosol);GO:0003777(microtubule motor activity);GO:0016604(nuclear body);GO:0008017(microtubule binding);GO:0005874(microtubule);GO:0003774(motor activity);GO:0007018(microtubule-based movement);GO:1990752(microtubule end);GO:0005737(cytoplasm);GO:0051301(cell division);GO:0005856(cytoskeleton);GO:0007049(cell cycle);GO:0005515(protein binding);GO:0016887(ATPase activity);GO:0000070(mitotic sister chromatid segregation);GO:0005871(kinesin complex);GO:0051302(regulation of cell division);GO:0000278(mitotic cell cycle);GO:0019894(kinesin binding);GO:0035371(microtubule plus-end);GO:0000235(astral microtubule);GO:0007019(microtubule depolymerization)","NA","NA","NA","kinesin family member 18B [Source:HGNC Symbol;Acc:HGNC:27102]",{"v":0.26052453877551,"d":"0.26"},{"v":0.05038658216971,"d":"0.05"},{"v":5.17051420352391,"d":"5.17"},{"v":2.37030776254893,"d":"2.37"},1,1,"up","no"]
["ENSG00000269118","FAM90A28P","ENST00000597191","NA","NA","NA","NA","family with sequence similarity 90 member A28, pseudogene [Source:HGNC Symbol;Acc:HGNC:43747]",0,{"v":0.0241130344456405,"d":"0.02"},"-inf","-inf",1,1,"down","no"]
["ENSG00000230549","USP17L1","ENST00000529559","GO:0005634(nucleus);GO:0016579(protein deubiquitination);GO:0016787(hydrolase activity);GO:0005783(endoplasmic reticulum);GO:0008233(peptidase activity);GO:0008234(cysteine-type peptidase activity);GO:0006508(proteolysis);GO:0006511(ubiquitin-dependent protein catabolic process);GO:0006915(apoptotic process);GO:0036459(thiol-dependent ubiquitinyl hydrolase activity)","NA","NA","NA","ubiquitin specific peptidase 17-like family member 1 [Source:HGNC Symbol;Acc:HGNC:37182]",{"v":0.076312,"d":"0.08"},0,"inf","inf",1,1,"up","no"]
["ENSG00000166396","SERPINB7","ENST00000398019","GO:0005615(extracellular space);GO:0005737(cytoplasm);GO:0010951(negative regulation of endopeptidase activity);GO:0030414(peptidase inhibitor activity);GO:0010466(negative regulation of peptidase activity);GO:0004867(serine-type endopeptidase inhibitor activity);GO:0032914(positive regulation of transforming growth factor beta1 production);GO:0032967(positive regulation of collagen biosynthetic process);GO:0072126(positive regulation of glomerular mesangial cell proliferation);GO:0090362(positive regulation of platelet-derived growth factor production)","NA","NA","NA","serpin family B member 7 [Source:HGNC Symbol;Acc:HGNC:13902]",{"v":0.0122547618505878,"d":"0.01"},0,"inf","inf",1,1,"up","no"]
["ENSG00000204528","PSORS1C3","ENST00000412143","NA","NA","NA","NA","psoriasis susceptibility 1 candidate 3 (non-protein coding) [Source:HGNC Symbol;Acc:HGNC:17203]",0,{"v":0.016799,"d":"0.02"},"-inf","-inf",1,1,"down","no"]
["ENSG00000279395","OR5L1","ENST00000625203","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0004930(G-protein coupled receptor activity);GO:0007186(G-protein coupled receptor signaling pathway);GO:0005886(plasma membrane);GO:0004871(signal transducer activity);GO:0007165(signal transduction);GO:0004984(olfactory receptor activity);GO:0007608(sensory perception of smell);GO:0050896(response to stimulus);GO:0050911(detection of chemical stimulus involved in sensory perception of smell);GO:0005549(odorant binding)","04740(Olfactory transduction)","K04257","NA","olfactory receptor family 5 subfamily L member 1 (gene/pseudogene) [Source:HGNC Symbol;Acc:HGNC:8350]",0,{"v":0.041103,"d":"0.04"},"-inf","-inf",1,1,"down","no"]
["ENSG00000231548","OR55B1P","ENST00000641518","NA","NA","NA","NA","olfactory receptor family 55 subfamily B member 1 pseudogene [Source:HGNC Symbol;Acc:HGNC:15241]",{"v":0.033796,"d":"0.03"},0,"inf","inf",1,1,"up","no"]
["MSTRG.3034","CACNA1C-AS1","ENST00000541673;ENST00000501371;ENST00000544517","NA","NA","NA","NA","CACNA1C antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:40119]",{"v":0.342673697612732,"d":"0.34"},{"v":0.183774485411141,"d":"0.18"},{"v":1.86464240041865,"d":"1.86"},{"v":0.898898978142926,"d":"0.90"},1,1,"up","no"]
["ENSG00000258410","AC087386.1","ENST00000553658","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000181097","AC105219.1","ENST00000531565","NA","NA","NA","NA",null,{"v":0.122112,"d":"0.12"},{"v":0.046484,"d":"0.05"},{"v":2.62696841924103,"d":"2.63"},{"v":1.39339885685593,"d":"1.39"},1,1,"up","no"]
["ENSG00000108813","DLX4","ENST00000411890;ENST00000611342;ENST00000503410;ENST00000240306;ENST00000503276","GO:0005634(nucleus);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0043565(sequence-specific DNA binding);GO:0005515(protein binding);GO:0007275(multicellular organism development);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:0001078(transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0000122(negative regulation of transcription from RNA polymerase II promoter)","NA","NA","NA","distal-less homeobox 4 [Source:HGNC Symbol;Acc:HGNC:2917]",{"v":0.101590653677278,"d":"0.10"},{"v":0.112906461580681,"d":"0.11"},{"v":0.899777145213988,"d":"0.90"},{"v":-0.152360372674999,"d":"-0.15"},1,1,"down","no"]
["ENSG00000269946","AL158152.2","ENST00000602703","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000168530","MYL1","ENST00000341685","GO:0005509(calcium ion binding);GO:0016459(myosin complex);GO:0005829(cytosol);GO:0008307(structural constituent of muscle);GO:0030049(muscle filament sliding);GO:0006936(muscle contraction);GO:0005859(muscle myosin complex);GO:0030016(myofibril);GO:0030017(sarcomere);GO:0060048(cardiac muscle contraction);GO:0043292(contractile fiber)","NA","NA","NA","myosin light chain 1 [Source:HGNC Symbol;Acc:HGNC:7582]",{"v":0.0133229284649776,"d":"0.01"},0,"inf","inf",1,1,"up","no"]
["ENSG00000179799","OR7E22P","ENST00000478335","NA","NA","NA","NA","olfactory receptor family 7 subfamily E member 22 pseudogene [Source:HGNC Symbol;Acc:HGNC:8394]",0,{"v":0.0357273570869225,"d":"0.04"},"-inf","-inf",1,1,"down","no"]
["ENSG00000263412","AC004477.1","ENST00000578660","NA","NA","NA","NA",null,{"v":0.0525764473235595,"d":"0.05"},{"v":0.0466661609273781,"d":"0.05"},{"v":1.12665036674817,"d":"1.13"},{"v":0.172039873613201,"d":"0.17"},1,1,"up","no"]
["ENSG00000129946","SHC2","ENST00000590222;ENST00000588376;ENST00000264554;ENST00000587423","GO:0035556(intracellular signal transduction);GO:0043547(positive regulation of GTPase activity);GO:0005515(protein binding);GO:0000187(activation of MAPK activity);GO:0030971(receptor tyrosine kinase binding);GO:0005886(plasma membrane);GO:0005575(cellular_component);GO:0005829(cytosol);GO:0000165(MAPK cascade);GO:0005088(Ras guanyl-nucleotide exchange factor activity);GO:0048010(vascular endothelial growth factor receptor signaling pathway);GO:0007169(transmembrane receptor protein tyrosine kinase signaling pathway);GO:0007265(Ras protein signal transduction);GO:0005622(intracellular);GO:0005622(intracellular)","04014(Ras signaling pathway);04012(ErbB signaling pathway);04370(VEGF signaling pathway);04072(Phospholipase D signaling pathway);04510(Focal adhesion);04650(Natural killer cell mediated cytotoxicity);04062(Chemokine signaling pathway);04910(Insulin signaling pathway);04915(Estrogen signaling pathway);04917(Prolactin signaling pathway);04926(Relaxin signaling pathway);04722(Neurotrophin signaling pathway);05225(Hepatocellular carcinoma);05226(Gastric cancer);05214(Glioma);05220(Chronic myeloid leukemia);05224(Breast cancer);05034(Alcoholism);05100(Bacterial invasion of epithelial cells);01521(EGFR tyrosine kinase inhibitor resistance);01522(Endocrine resistance);01522(Endocrine resistance)","K17447","NA","SHC adaptor protein 2 [Source:HGNC Symbol;Acc:HGNC:29869]",{"v":0.0376987044299201,"d":"0.04"},{"v":0.0252466937787461,"d":"0.03"},{"v":1.49321351778967,"d":"1.49"},{"v":0.578420474267851,"d":"0.58"},1,1,"up","no"]
["ENSG00000263818","AC091178.1","ENST00000578423;ENST00000583447","NA","NA","NA","NA",null,{"v":0.0249987801486454,"d":"0.02"},0,"inf","inf",1,1,"up","no"]
["ENSG00000123095","BHLHE41","ENST00000541271;ENST00000394326;ENST00000242728","GO:0010832(negative regulation of myotube differentiation);GO:0005634(nucleus);GO:0046983(protein dimerization activity);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0048511(rhythmic process);GO:0030154(cell differentiation);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:0000981(RNA polymerase II transcription factor activity, sequence-specific DNA binding);GO:0001078(transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0001102(RNA polymerase II activating transcription factor binding);GO:0001191(transcriptional repressor activity, RNA polymerase II transcription factor binding);GO:0003705(transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding);GO:0003714(transcription corepressor activity);GO:0042803(protein homodimerization activity);GO:0042826(histone deacetylase binding);GO:0043425(bHLH transcription factor binding);GO:0043426(MRF binding);GO:0046982(protein heterodimerization activity);GO:0070888(E-box binding);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0007623(circadian rhythm);GO:0010944(negative regulation of transcription by competitive promoter binding);GO:0032922(circadian regulation of gene expression);GO:0045892(negative regulation of transcription, DNA-templated);GO:0005515(protein binding);GO:0008283(cell proliferation);GO:0009887(animal organ morphogenesis);GO:0009887(animal organ morphogenesis)","04710(Circadian rhythm);04710(Circadian rhythm)","K03730","NA","basic helix-loop-helix family member e41 [Source:HGNC Symbol;Acc:HGNC:16617]",{"v":0.0714052796352584,"d":"0.07"},{"v":0.0448110987841945,"d":"0.04"},{"v":1.59347308083514,"d":"1.59"},{"v":0.672174647309254,"d":"0.67"},1,1,"up","no"]
["ENSG00000262140","AC010653.1","ENST00000571108","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["MSTRG.12036","AC093297.2","ENST00000505637","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000259520","AC051619.5","ENST00000559003","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000248880","ICE2P1","ENST00000512800","NA","NA","NA","NA","interactor of little elongation complex ELL subunit 2 pseudogene 1 [Source:HGNC Symbol;Acc:HGNC:48856]",0,{"v":0.019822,"d":"0.02"},"-inf","-inf",1,1,"down","no"]
["ENSG00000275318","AL136981.2","ENST00000617319","NA","NA","NA","NA",null,{"v":0.209857,"d":"0.21"},0,"inf","inf",1,1,"up","no"]
["MSTRG.13592","TRGVA","ENST00000413819","NA","NA","NA","NA","T-cell receptor gamma variable A (pseudogene) [Source:HGNC Symbol;Acc:HGNC:12296]",0,{"v":0.621826,"d":"0.62"},"-inf","-inf",1,1,"down","no"]
["ENSG00000235902","AC108472.1","ENST00000447277","NA","NA","NA","NA",null,{"v":0.083175,"d":"0.08"},0,"inf","inf",1,1,"up","no"]
["ENSG00000171478","SPACA5B","ENST00000304270","GO:0016787(hydrolase activity);GO:0008152(metabolic process);GO:0005576(extracellular region);GO:0016798(hydrolase activity, acting on glycosyl bonds);GO:0005615(extracellular space);GO:0003796(lysozyme activity);GO:0050829(defense response to Gram-negative bacterium);GO:0016998(cell wall macromolecule catabolic process);GO:0050830(defense response to Gram-positive bacterium)","NA","NA","NA","sperm acrosome associated 5B [Source:HGNC Symbol;Acc:HGNC:19142]",{"v":0.042166,"d":"0.04"},{"v":0.027748,"d":"0.03"},{"v":1.51960501657777,"d":"1.52"},{"v":0.603696379803074,"d":"0.60"},1,1,"up","no"]
["ENSG00000281100","AC105749.1","ENST00000631338","NA","NA","NA","NA",null,{"v":0.57523,"d":"0.58"},{"v":0.296393,"d":"0.30"},{"v":1.94076783189886,"d":"1.94"},{"v":0.956627543192355,"d":"0.96"},1,1,"up","no"]
["MSTRG.1609","PIP4K2A","ENST00000605011","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0005886(plasma membrane);GO:0016307(phosphatidylinositol phosphate kinase activity);GO:0046488(phosphatidylinositol metabolic process);GO:0046854(phosphatidylinositol phosphorylation);GO:0005575(cellular_component);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0005776(autophagosome);GO:0006661(phosphatidylinositol biosynthetic process);GO:0014066(regulation of phosphatidylinositol 3-kinase signaling);GO:0016308(1-phosphatidylinositol-4-phosphate 5-kinase activity);GO:0052811(1-phosphatidylinositol-3-phosphate 4-kinase activity);GO:0010506(regulation of autophagy);GO:0006644(phospholipid metabolic process);GO:0016309(1-phosphatidylinositol-5-phosphate 4-kinase activity);GO:0035855(megakaryocyte development);GO:2000786(positive regulation of autophagosome assembly)","00562(Inositol phosphate metabolism);04070(Phosphatidylinositol signaling system);04810(Regulation of actin cytoskeleton)","NA","NA","phosphatidylinositol-5-phosphate 4-kinase type 2 alpha [Source:HGNC Symbol;Acc:HGNC:8997]",0,{"v":0.033114,"d":"0.03"},"-inf","-inf",1,1,"down","no"]
["ENSG00000170324","FRMPD2","ENST00000637395;ENST00000463706;ENST00000374201","GO:0005856(cytoskeleton);GO:0070830(bicellular tight junction assembly);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005886(plasma membrane);GO:0030054(cell junction);GO:0005923(bicellular tight junction);GO:0005515(protein binding);GO:0016323(basolateral plasma membrane);GO:0005545(1-phosphatidylinositol binding);GO:0005545(1-phosphatidylinositol binding)","NA","NA","NA","FERM and PDZ domain containing 2 [Source:HGNC Symbol;Acc:HGNC:28572]",{"v":0.0253431060175179,"d":"0.03"},{"v":0.0177512584461381,"d":"0.02"},{"v":1.42767940055717,"d":"1.43"},{"v":0.513672044384584,"d":"0.51"},1,1,"up","no"]
["ENSG00000082684","SEMA5B","ENST00000616742;ENST00000451055","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0007275(multicellular organism development);GO:0007399(nervous system development);GO:0030154(cell differentiation);GO:0005615(extracellular space);GO:0038191(neuropilin binding);GO:0050919(negative chemotaxis);GO:0048675(axon extension);GO:0050908(detection of light stimulus involved in visual perception);GO:0097485(neuron projection guidance);GO:1990138(neuron projection extension);GO:1990138(neuron projection extension)","04360(Axon guidance);04360(Axon guidance)","K06841","NA","semaphorin 5B [Source:HGNC Symbol;Acc:HGNC:10737]",{"v":0.0214677438946015,"d":"0.02"},{"v":0.0340674358933162,"d":"0.03"},{"v":0.630154378563411,"d":"0.63"},{"v":-0.666222783887642,"d":"-0.67"},1,1,"down","no"]
["ENSG00000217261","POM121L4P","ENST00000427789","NA","NA","NA","NA","POM121 transmembrane nucleoporin like 4, pseudogene [Source:HGNC Symbol;Acc:HGNC:19326]",0,{"v":0.00185,"d":"0.00"},"-inf","-inf",1,1,"down","no"]
["ENSG00000122367","LDB3","ENST00000372066;ENST00000429277;ENST00000361373","GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0005856(cytoskeleton);GO:0042995(cell projection);GO:0048471(perinuclear region of cytoplasm);GO:0005515(protein binding);GO:0030018(Z disc);GO:0008092(cytoskeletal protein binding);GO:0031143(pseudopodium);GO:0005080(protein kinase C binding);GO:0051371(muscle alpha-actinin binding);GO:0045214(sarcomere organization);GO:0045214(sarcomere organization)","NA","NA","NA","LIM domain binding 3 [Source:HGNC Symbol;Acc:HGNC:15710]",{"v":0.0593954339424805,"d":"0.06"},{"v":2.77906950269623E-3,"d":"0.00"},{"v":21.3724175969171,"d":"21.37"},{"v":4.41767820633884,"d":"4.42"},1,1,"up","no"]
["ENSG00000132832","LINC01260","ENST00000415889","NA","NA","NA","NA","long intergenic non-protein coding RNA 1260 [Source:HGNC Symbol;Acc:HGNC:49900]",{"v":0.355572,"d":"0.36"},{"v":0.325639,"d":"0.33"},{"v":1.09192080801133,"d":"1.09"},{"v":0.126868228023106,"d":"0.13"},1,1,"up","no"]
["ENSG00000198128","OR2L3","ENST00000641649","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0004930(G-protein coupled receptor activity);GO:0007186(G-protein coupled receptor signaling pathway);GO:0005886(plasma membrane);GO:0004871(signal transducer activity);GO:0007165(signal transduction);GO:0004984(olfactory receptor activity);GO:0007608(sensory perception of smell);GO:0050896(response to stimulus);GO:0050911(detection of chemical stimulus involved in sensory perception of smell);GO:0003674(molecular_function);GO:0008150(biological_process)","04740(Olfactory transduction)","NA","NA","olfactory receptor family 2 subfamily L member 3 [Source:HGNC Symbol;Acc:HGNC:15009]",{"v":0.0175491997268692,"d":"0.02"},0,"inf","inf",1,1,"up","no"]
["MSTRG.3553","ATXN7L3B","ENST00000519948","NA","NA","NA","NA","ataxin 7 like 3B [Source:HGNC Symbol;Acc:HGNC:37931]",0,0,1,0,1,1,"no","no"]
["ENSG00000197085","NPSR1-AS1","ENST00000419766","NA","NA","NA","NA","NPSR1 antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:22128]",0,{"v":3.21038164931044E-3,"d":"0.00"},"-inf","-inf",1,1,"down","no"]
["ENSG00000108231","LGI1","ENST00000636946;ENST00000626307","GO:0005576(extracellular region);GO:0030054(cell junction);GO:0045202(synapse);GO:0050806(positive regulation of synaptic transmission);GO:0051260(protein homooligomerization);GO:0005615(extracellular space);GO:0007399(nervous system development);GO:0008283(cell proliferation);GO:0005515(protein binding);GO:0005102(receptor binding);GO:0007411(axon guidance);GO:0030307(positive regulation of cell growth);GO:0031175(neuron projection development);GO:0031175(neuron projection development)","NA","NA","NA","leucine rich glioma inactivated 1 [Source:HGNC Symbol;Acc:HGNC:6572]",{"v":0.00462762981634858,"d":"0.00"},{"v":0.00692115232265034,"d":"0.01"},{"v":0.668621293191898,"d":"0.67"},{"v":-0.580738794533906,"d":"-0.58"},1,1,"down","no"]
["ENSG00000165730","STOX1","ENST00000399169;ENST00000298596","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0001650(fibrillar center);GO:0051301(cell division);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0007049(cell cycle);GO:0005730(nucleolus);GO:0005813(centrosome);GO:0005815(microtubule organizing center);GO:0010800(positive regulation of peptidyl-threonine phosphorylation);GO:0033138(positive regulation of peptidyl-serine phosphorylation);GO:0010628(positive regulation of gene expression);GO:0008284(positive regulation of cell proliferation);GO:0010629(negative regulation of gene expression);GO:0010971(positive regulation of G2/M transition of mitotic cell cycle);GO:0010821(regulation of mitochondrion organization);GO:0000977(RNA polymerase II regulatory region sequence-specific DNA binding);GO:0061418(regulation of transcription from RNA polymerase II promoter in response to hypoxia);GO:1902882(regulation of response to oxidative stress);GO:0010468(regulation of gene expression);GO:0051881(regulation of mitochondrial membrane potential);GO:0045787(positive regulation of cell cycle);GO:0048839(inner ear development);GO:0050679(positive regulation of epithelial cell proliferation);GO:0051897(positive regulation of protein kinase B signaling);GO:0071500(cellular response to nitrosative stress);GO:1901858(regulation of mitochondrial DNA metabolic process);GO:1904031(positive regulation of cyclin-dependent protein kinase activity);GO:1904120(positive regulation of otic vesicle morphogenesis);GO:0005938(cell cortex);GO:0005938(cell cortex)","NA","NA","NA","storkhead box 1 [Source:HGNC Symbol;Acc:HGNC:23508]",{"v":0.0510951079035874,"d":"0.05"},{"v":0.0563262399103139,"d":"0.06"},{"v":0.907127974190079,"d":"0.91"},{"v":-0.140621999805578,"d":"-0.14"},1,1,"down","no"]
["MSTRG.5783","AC145285.7","ENST00000614819","NA","NA","NA","NA",null,0,{"v":0.347342,"d":"0.35"},"-inf","-inf",1,1,"down","no"]
["MSTRG.6746","PIGW","ENST00000620233;ENST00000614443","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016746(transferase activity, transferring acyl groups);GO:0006506(GPI anchor biosynthetic process);GO:0016740(transferase activity);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0072659(protein localization to plasma membrane);GO:0016254(preassembly of GPI anchor in ER membrane);GO:0008374(O-acyltransferase activity);GO:0006505(GPI anchor metabolic process);GO:0006505(GPI anchor metabolic process)","00563(Glycosylphosphatidylinositol(GPI)-anchor biosynthesis);00563(Glycosylphosphatidylinositol(GPI)-anchor biosynthesis)","K05283","EC:2.3.-.-","phosphatidylinositol glycan anchor biosynthesis class W [Source:HGNC Symbol;Acc:HGNC:23213]",{"v":0.516958799571275,"d":"0.52"},{"v":0.127520966059307,"d":"0.13"},{"v":4.05391219613918,"d":"4.05"},{"v":2.01931484174848,"d":"2.02"},1,1,"up","no"]
["MSTRG.13314","AL158850.1","ENST00000441249","NA","NA","NA","NA",null,{"v":0.056239,"d":"0.06"},{"v":0.395697,"d":"0.40"},{"v":0.142126425017122,"d":"0.14"},{"v":-2.81475328065232,"d":"-2.81"},1,1,"down","no"]
["MSTRG.11365","AC108734.3","ENST00000481241","NA","NA","NA","NA",null,{"v":0.22061,"d":"0.22"},{"v":0.253771,"d":"0.25"},{"v":0.869327070469045,"d":"0.87"},{"v":-0.202029024674939,"d":"-0.20"},1,1,"down","no"]
["ENSG00000253781","ZNF317P1","ENST00000521453","NA","NA","NA","NA","zinc finger protein 317 pseudogene 1 [Source:HGNC Symbol;Acc:HGNC:31062]",{"v":0.045713,"d":"0.05"},0,"inf","inf",1,1,"up","no"]
["ENSG00000258234","AC024257.1","ENST00000547523","NA","NA","NA","NA",null,{"v":0.044168,"d":"0.04"},0,"inf","inf",1,1,"up","no"]
["ENSG00000171711","DEFB4A","ENST00000302247","GO:0005576(extracellular region);GO:0005615(extracellular space);GO:0006935(chemotaxis);GO:0006952(defense response);GO:0042742(defense response to bacterium);GO:0005515(protein binding);GO:0050829(defense response to Gram-negative bacterium);GO:0005622(intracellular);GO:0050830(defense response to Gram-positive bacterium);GO:0061844(antimicrobial humoral immune response mediated by antimicrobial peptide);GO:0007186(G-protein coupled receptor signaling pathway);GO:0006955(immune response);GO:0019730(antimicrobial humoral response);GO:0005796(Golgi lumen);GO:0031731(CCR6 chemokine receptor binding);GO:0031640(killing of cells of other organism)","04657(IL-17 signaling pathway)","K21100","NA","defensin beta 4A [Source:HGNC Symbol;Acc:HGNC:2767]",0,{"v":0.004971,"d":"0.00"},"-inf","-inf",1,1,"down","no"]
["ENSG00000003137","CYP26B1","ENST00000001146","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0046872(metal ion binding);GO:0004497(monooxygenase activity);GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005506(iron ion binding);GO:0016705(oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen);GO:0020037(heme binding);GO:0006805(xenobiotic metabolic process);GO:0043231(intracellular membrane-bounded organelle);GO:0060349(bone morphogenesis);GO:0016709(oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen);GO:0031090(organelle membrane);GO:0006766(vitamin metabolic process);GO:0001972(retinoic acid binding);GO:0008401(retinoic acid 4-hydroxylase activity);GO:0016125(sterol metabolic process);GO:0034653(retinoic acid catabolic process);GO:0048387(negative regulation of retinoic acid receptor signaling pathway);GO:0030326(embryonic limb morphogenesis);GO:0007283(spermatogenesis);GO:0001709(cell fate determination);GO:0001768(establishment of T cell polarity);GO:0006954(inflammatory response);GO:0007140(male meiotic nuclear division);GO:0009954(proximal/distal pattern formation);GO:0010628(positive regulation of gene expression);GO:0042573(retinoic acid metabolic process);GO:0043587(tongue morphogenesis);GO:0045580(regulation of T cell differentiation);GO:0048384(retinoic acid receptor signaling pathway);GO:0048385(regulation of retinoic acid receptor signaling pathway);GO:0061436(establishment of skin barrier);GO:0070268(cornification);GO:0071300(cellular response to retinoic acid);GO:2001037(positive regulation of tongue muscle cell differentiation)","00830(Retinol metabolism)","K12664","NA","cytochrome P450 family 26 subfamily B member 1 [Source:HGNC Symbol;Acc:HGNC:20581]",0,{"v":0.0179532929212363,"d":"0.02"},"-inf","-inf",1,1,"down","no"]
["MSTRG.7946","AC024075.3","ENST00000601040;ENST00000601687","NA","NA","NA","NA",null,{"v":0.310928651031895,"d":"0.31"},{"v":0.0646980825515947,"d":"0.06"},{"v":4.80584027793929,"d":"4.81"},{"v":2.26478870130714,"d":"2.26"},1,1,"up","no"]
["ENSG00000227056","RPL6P2","ENST00000425480","NA","NA","NA","NA","ribosomal protein L6 pseudogene 2 [Source:HGNC Symbol;Acc:HGNC:35964]",0,0,1,0,1,1,"no","no"]
["MSTRG.10480","ENTHD1","ENST00000325157","NA","NA","NA","NA","ENTH domain containing 1 [Source:HGNC Symbol;Acc:HGNC:26352]",{"v":0.0251310984354628,"d":"0.03"},{"v":0.088828464797914,"d":"0.09"},{"v":0.282917176297445,"d":"0.28"},{"v":-1.82154832746069,"d":"-1.82"},1,1,"down","no"]
["MSTRG.7853","MIR6515","ENST00000619843","NA","NA","NA","NA","microRNA 6515 [Source:HGNC Symbol;Acc:HGNC:50227]",{"v":0.010521,"d":"0.01"},{"v":0.88307,"d":"0.88"},{"v":0.0119141177936064,"d":"0.01"},{"v":-6.39118406173877,"d":"-6.39"},1,1,"down","no"]
["ENSG00000231381","RNF2P1","ENST00000442955","NA","NA","NA","NA","ring finger protein 2 pseudogene 1 [Source:HGNC Symbol;Acc:HGNC:33987]",{"v":0.050893,"d":"0.05"},0,"inf","inf",1,1,"up","no"]
["ENSG00000267243","AC005381.1","ENST00000592716;ENST00000585697;ENST00000593065","NA","NA","NA","NA",null,{"v":0.0627453015748032,"d":"0.06"},{"v":0.422230046456693,"d":"0.42"},{"v":0.148604539400629,"d":"0.15"},{"v":-2.7504499085482,"d":"-2.75"},1,1,"down","no"]
["ENSG00000278819","AC005156.1","ENST00000613371","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000224785","AC006026.1","ENST00000444025","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000164100","NDST3","ENST00000296499","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016740(transferase activity);GO:0016787(hydrolase activity);GO:0005794(Golgi apparatus);GO:0003824(catalytic activity);GO:0008152(metabolic process);GO:0000139(Golgi membrane);GO:0008146(sulfotransferase activity);GO:0005575(cellular_component);GO:0015016([heparan sulfate]-glucosamine N-sulfotransferase activity);GO:0015012(heparan sulfate proteoglycan biosynthetic process);GO:0030210(heparin biosynthetic process);GO:0042328(heparan sulfate N-acetylglucosaminyltransferase activity);GO:0015014(heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process)","00534(Glycosaminoglycan biosynthesis - heparan sulfate / heparin)","K02578","EC:3.1.1.-;EC:2.8.2.-","N-deacetylase and N-sulfotransferase 3 [Source:HGNC Symbol;Acc:HGNC:7682]",{"v":0.00609792695106292,"d":"0.01"},0,"inf","inf",1,1,"up","no"]
["ENSG00000165568","AKR1E2","ENST00000525627;ENST00000474119;ENST00000525281;ENST00000463345","GO:0005794(Golgi apparatus);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0005737(cytoplasm);GO:0070062(extracellular exosome);GO:0050571(1,5-anhydro-D-fructose reductase activity);GO:0050571(1,5-anhydro-D-fructose reductase activity)","NA","NA","NA","aldo-keto reductase family 1 member E2 [Source:HGNC Symbol;Acc:HGNC:23437]",{"v":0.0212671266032271,"d":"0.02"},{"v":0.0951576172941663,"d":"0.10"},{"v":0.223493685613027,"d":"0.22"},{"v":-2.16169402349425,"d":"-2.16"},1,1,"down","no"]
["ENSG00000261764","KRT18P18","ENST00000565278","NA","NA","NA","NA","keratin 18 pseudogene 18 [Source:HGNC Symbol;Acc:HGNC:33386]",{"v":0.040189,"d":"0.04"},0,"inf","inf",1,1,"up","no"]
["MSTRG.2729","LRRC32","ENST00000260061;ENST00000464145;ENST00000407242","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005887(integral component of plasma membrane);GO:0010628(positive regulation of gene expression);GO:0046007(negative regulation of activated T cell proliferation);GO:0050710(negative regulation of cytokine secretion);GO:0050710(negative regulation of cytokine secretion)","NA","NA","NA","leucine rich repeat containing 32 [Source:HGNC Symbol;Acc:HGNC:4161]",{"v":0.118082147566719,"d":"0.12"},{"v":0.133389629737609,"d":"0.13"},{"v":0.88524233704673,"d":"0.89"},{"v":-0.175855644667138,"d":"-0.18"},1,1,"down","no"]
["ENSG00000152661","GJA1","ENST00000282561","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005783(endoplasmic reticulum);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0004871(signal transducer activity);GO:0005921(gap junction);GO:0030054(cell junction);GO:0022857(transmembrane transporter activity);GO:0007154(cell communication);GO:0005925(focal adhesion);GO:0005922(connexin complex);GO:0007507(heart development);GO:0005887(integral component of plasma membrane);GO:0005789(endoplasmic reticulum membrane);GO:0070062(extracellular exosome);GO:0006810(transport);GO:0043123(positive regulation of I-kappaB kinase/NF-kappaB signaling);GO:0007267(cell-cell signaling);GO:0006936(muscle contraction);GO:0030308(negative regulation of cell growth);GO:0000139(Golgi membrane);GO:0005739(mitochondrion);GO:0007165(signal transduction);GO:0045121(membrane raft);GO:0005794(Golgi apparatus);GO:0014704(intercalated disc);GO:0086064(cell communication by electrical coupling involved in cardiac conduction);GO:0016264(gap junction assembly);GO:0030660(Golgi-associated vesicle membrane);GO:0005243(gap junction channel activity);GO:0015075(ion transmembrane transporter activity);GO:0017124(SH3 domain binding);GO:0019904(protein domain specific binding);GO:0030165(PDZ domain binding);GO:0071253(connexin binding);GO:0086075(gap junction channel activity involved in cardiac conduction electrical coupling);GO:0097718(disordered domain specific binding);GO:1903763(gap junction channel activity involved in cell communication by electrical coupling);GO:0001937(negative regulation of endothelial cell proliferation);GO:0002544(chronic inflammatory response);GO:0002931(response to ischemia);GO:0003104(positive regulation of glomerular filtration);GO:0003158(endothelium development);GO:0006915(apoptotic process);GO:0007204(positive regulation of cytosolic calcium ion concentration);GO:0008285(negative regulation of cell proliferation);GO:0009268(response to pH);GO:0009749(response to glucose);GO:0010232(vascular transport);GO:0010644(cell communication by electrical coupling);GO:0010652(positive regulation of cell communication by chemical coupling);GO:0015867(ATP transport);GO:0022898(regulation of transmembrane transporter activity);GO:0032024(positive regulation of insulin secretion);GO:0032496(response to lipopolysaccharide);GO:0032526(response to retinoic acid);GO:0034220(ion transmembrane transport);GO:0034405(response to fluid shear stress);GO:0043434(response to peptide hormone);GO:0045732(positive regulation of protein catabolic process);GO:0045907(positive regulation of vasoconstriction);GO:0046697(decidualization);GO:0048812(neuron projection morphogenesis);GO:0051259(protein oligomerization);GO:0051924(regulation of calcium ion transport);GO:0055085(transmembrane transport);GO:0060044(negative regulation of cardiac muscle cell proliferation);GO:0061045(negative regulation of wound healing);GO:0071260(cellular response to mechanical stimulus);GO:0071374(cellular response to parathyroid hormone stimulus);GO:0086014(atrial cardiac muscle cell action potential);GO:0097755(positive regulation of blood vessel diameter);GO:1905867(epididymis development);GO:2000279(negative regulation of DNA biosynthetic process);GO:2000810(regulation of bicellular tight junction assembly);GO:2000987(positive regulation of behavioral fear response);GO:0005737(cytoplasm);GO:0005741(mitochondrial outer membrane);GO:0005764(lysosome);GO:0005768(endosome);GO:0005769(early endosome);GO:0005770(late endosome);GO:0005771(multivesicular body);GO:0005916(fascia adherens);GO:0043234(protein complex)","04540(Gap junction);05412(Arrhythmogenic right ventricular cardiomyopathy (ARVC))","K07372","NA","gap junction protein alpha 1 [Source:HGNC Symbol;Acc:HGNC:4274]",{"v":0.080267,"d":"0.08"},{"v":0.025188,"d":"0.03"},{"v":3.18671589645863,"d":"3.19"},{"v":1.672070405046,"d":"1.67"},1,1,"up","no"]
["ENSG00000173237","C11orf86","ENST00000308963","NA","NA","NA","NA","chromosome 11 open reading frame 86 [Source:HGNC Symbol;Acc:HGNC:34442]",{"v":0.028682,"d":"0.03"},0,"inf","inf",1,1,"up","no"]
["ENSG00000253105","AP003548.1","ENST00000523862","NA","NA","NA","NA",null,{"v":0.0332667791586998,"d":"0.03"},0,"inf","inf",1,1,"up","no"]
["ENSG00000223711","AC069213.1","ENST00000426109;ENST00000415451","NA","NA","NA","NA",null,{"v":0.103320305475504,"d":"0.10"},{"v":0.0902023544668588,"d":"0.09"},{"v":1.14542803329446,"d":"1.15"},{"v":0.19588681763797,"d":"0.20"},1,1,"up","no"]
["ENSG00000196826","AC008758.1","ENST00000428311","NA","NA","NA","NA",null,0,{"v":0.004342,"d":"0.00"},"-inf","-inf",1,1,"down","no"]
["MSTRG.13209","METTL24","ENST00000338882","GO:0008168(methyltransferase activity);GO:0016740(transferase activity);GO:0032259(methylation);GO:0005576(extracellular region)","NA","NA","NA","methyltransferase like 24 [Source:HGNC Symbol;Acc:HGNC:21566]",{"v":0.0216142356257046,"d":"0.02"},{"v":0.0328919137542277,"d":"0.03"},{"v":0.657129159075654,"d":"0.66"},{"v":-0.605751134013425,"d":"-0.61"},1,1,"down","no"]
["ENSG00000146648","EGFR","ENST00000275493","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0007169(transmembrane receptor protein tyrosine kinase signaling pathway);GO:0018108(peptidyl-tyrosine phosphorylation);GO:0004714(transmembrane receptor protein tyrosine kinase activity);GO:0005622(intracellular);GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0004713(protein tyrosine kinase activity);GO:0005886(plasma membrane);GO:0023014(signal transduction by protein phosphorylation);GO:0004716(signal transducer, downstream of receptor, with protein tyrosine kinase activity);GO:0035556(intracellular signal transduction);GO:0006898(receptor-mediated endocytosis);GO:0008284(positive regulation of cell proliferation);GO:0051897(positive regulation of protein kinase B signaling);GO:0070374(positive regulation of ERK1 and ERK2 cascade);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005794(Golgi apparatus);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0043547(positive regulation of GTPase activity);GO:0005515(protein binding);GO:0007165(signal transduction);GO:0005576(extracellular region);GO:0000139(Golgi membrane);GO:0007275(multicellular organism development);GO:0005615(extracellular space);GO:0045121(membrane raft);GO:0005925(focal adhesion);GO:0004709(MAP kinase kinase kinase activity);GO:0046854(phosphatidylinositol phosphorylation);GO:0042802(identical protein binding);GO:0046718(viral entry into host cell);GO:0005768(endosome);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0045296(cadherin binding);GO:0051015(actin filament binding);GO:0001934(positive regulation of protein phosphorylation);GO:0033138(positive regulation of peptidyl-serine phosphorylation);GO:0061024(membrane organization);GO:0000165(MAPK cascade);GO:0003682(chromatin binding);GO:0008283(cell proliferation);GO:0030335(positive regulation of cell migration);GO:0043234(protein complex);GO:0010008(endosome membrane);GO:0031625(ubiquitin protein ligase binding);GO:0031901(early endosome membrane);GO:0003690(double-stranded DNA binding);GO:0001503(ossification);GO:0043066(negative regulation of apoptotic process);GO:0031965(nuclear membrane);GO:0019899(enzyme binding);GO:0019903(protein phosphatase binding);GO:0009986(cell surface);GO:0046982(protein heterodimerization activity);GO:0046934(phosphatidylinositol-4,5-bisphosphate 3-kinase activity);GO:0014066(regulation of phosphatidylinositol 3-kinase signaling);GO:0038111(interleukin-7-mediated signaling pathway);GO:0048015(phosphatidylinositol-mediated signaling);GO:0046777(protein autophosphorylation);GO:0007173(epidermal growth factor receptor signaling pathway);GO:0005088(Ras guanyl-nucleotide exchange factor activity);GO:0030307(positive regulation of cell growth);GO:0038128(ERBB2 signaling pathway);GO:1901185(negative regulation of ERBB signaling pathway);GO:2000145(regulation of cell motility);GO:0042177(negative regulation of protein catabolic process);GO:0042327(positive regulation of phosphorylation);GO:0045740(positive regulation of DNA replication);GO:0042059(negative regulation of epidermal growth factor receptor signaling pathway);GO:0034614(cellular response to reactive oxygen species);GO:0045893(positive regulation of transcription, DNA-templated);GO:0071276(cellular response to cadmium ion);GO:0001618(virus receptor activity);GO:0043235(receptor complex);GO:0016337(single organismal cell-cell adhesion);GO:0006950(response to stress);GO:0045739(positive regulation of DNA repair);GO:0050679(positive regulation of epithelial cell proliferation);GO:0030665(clathrin-coated vesicle membrane);GO:0051205(protein insertion into membrane);GO:0071364(cellular response to epidermal growth factor stimulus);GO:0071392(cellular response to estradiol stimulus);GO:1901224(positive regulation of NIK/NF-kappaB signaling);GO:0043406(positive regulation of MAP kinase activity);GO:0035413(positive regulation of catenin import into nucleus);GO:0030122(AP-2 adaptor complex);GO:0038083(peptidyl-tyrosine autophosphorylation);GO:0030235(nitric-oxide synthase regulator activity);GO:0004888(transmembrane signaling receptor activity);GO:0005006(epidermal growth factor-activated receptor activity);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0007166(cell surface receptor signaling pathway);GO:0007202(activation of phospholipase C activity);GO:0007611(learning or memory);GO:0031659(positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle);GO:0043006(activation of phospholipase A2 activity by calcium-mediated signaling);GO:0045429(positive regulation of nitric oxide biosynthetic process);GO:0046328(regulation of JNK cascade);GO:0050730(regulation of peptidyl-tyrosine phosphorylation);GO:0050999(regulation of nitric-oxide synthase activity);GO:0070141(response to UV-A);GO:0070372(regulation of ERK1 and ERK2 cascade);GO:1900020(positive regulation of protein kinase C activity);GO:1903078(positive regulation of protein localization to plasma membrane);GO:1903800(positive regulation of production of miRNAs involved in gene silencing by miRNA);GO:1905208(negative regulation of cardiocyte differentiation);GO:0016323(basolateral plasma membrane);GO:0070435(Shc-EGFR complex);GO:0097489(multivesicular body, internal vesicle lumen);GO:0004871(signal transducer activity);GO:0005102(receptor binding);GO:0005178(integrin binding);GO:0005516(calmodulin binding);GO:0019901(protein kinase binding);GO:0048408(epidermal growth factor binding);GO:0000186(activation of MAPKK activity);GO:0000902(cell morphogenesis);GO:0001889(liver development);GO:0001892(embryonic placenta development);GO:0001942(hair follicle development);GO:0006412(translation);GO:0006970(response to osmotic stress);GO:0006979(response to oxidative stress);GO:0007435(salivary gland morphogenesis);GO:0007494(midgut development);GO:0007623(circadian rhythm);GO:0008544(epidermis development);GO:0010960(magnesium ion homeostasis);GO:0014070(response to organic cyclic compound);GO:0016101(diterpenoid metabolic process);GO:0021795(cerebral cortex cell migration);GO:0030324(lung development);GO:0032355(response to estradiol);GO:0032930(positive regulation of superoxide anion generation);GO:0033590(response to cobalamin);GO:0033594(response to hydroxyisoflavone);GO:0033993(response to lipid);GO:0035690(cellular response to drug);GO:0042060(wound healing);GO:0042127(regulation of cell proliferation);GO:0042698(ovulation cycle);GO:0042743(hydrogen peroxide metabolic process);GO:0043586(tongue development);GO:0045780(positive regulation of bone resorption);GO:0045907(positive regulation of vasoconstriction);GO:0045930(negative regulation of mitotic cell cycle);GO:0048143(astrocyte activation);GO:0048146(positive regulation of fibroblast proliferation);GO:0048546(digestive tract morphogenesis);GO:0048661(positive regulation of smooth muscle cell proliferation);GO:0048812(neuron projection morphogenesis);GO:0050729(positive regulation of inflammatory response);GO:0051592(response to calcium ion);GO:0051968(positive regulation of synaptic transmission, glutamatergic);GO:0060571(morphogenesis of an epithelial fold);GO:0061029(eyelid development in camera-type eye);GO:0071230(cellular response to amino acid stimulus);GO:0071260(cellular response to mechanical stimulus);GO:0071363(cellular response to growth factor stimulus);GO:0071549(cellular response to dexamethasone stimulus);GO:0097421(liver regeneration);GO:0097755(positive regulation of blood vessel diameter);GO:1902722(positive regulation of prolactin secretion);GO:0016324(apical plasma membrane);GO:0030139(endocytic vesicle);GO:0045202(synapse);GO:0048471(perinuclear region of cytoplasm)","04014(Ras signaling pathway);04015(Rap1 signaling pathway);04010(MAPK signaling pathway);04012(ErbB signaling pathway);04630(Jak-STAT signaling pathway);04066(HIF-1 signaling pathway);04068(FoxO signaling pathway);04020(Calcium signaling pathway);04072(Phospholipase D signaling pathway);04151(PI3K-Akt signaling pathway);04060(Cytokine-cytokine receptor interaction);04144(Endocytosis);04510(Focal adhesion);04520(Adherens junction);04540(Gap junction);04810(Regulation of actin cytoskeleton);04912(GnRH signaling pathway);04915(Estrogen signaling pathway);04921(Oxytocin signaling pathway);04926(Relaxin signaling pathway);05200(Pathways in cancer);05230(Central carbon metabolism in cancer);05231(Choline metabolism in cancer);05206(MicroRNAs in cancer);05205(Proteoglycans in cancer);05212(Pancreatic cancer);05225(Hepatocellular carcinoma);05226(Gastric cancer);05214(Glioma);05218(Melanoma);05219(Bladder cancer);05215(Prostate cancer);05213(Endometrial cancer);05224(Breast cancer);05223(Non-small cell lung cancer);05120(Epithelial cell signaling in Helicobacter pylori infection);05160(Hepatitis C);05165(Human papillomavirus infection);01521(EGFR tyrosine kinase inhibitor resistance);01522(Endocrine resistance)","K04361","EC:2.7.10.1","epidermal growth factor receptor [Source:HGNC Symbol;Acc:HGNC:3236]",{"v":0.00800755442856002,"d":"0.01"},{"v":0.0125811708330006,"d":"0.01"},{"v":0.636471321695759,"d":"0.64"},{"v":-0.651832584656122,"d":"-0.65"},1,1,"down","no"]
["ENSG00000120054","CPN1","ENST00000370418","GO:0005615(extracellular space);GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0016787(hydrolase activity);GO:0008233(peptidase activity);GO:0006508(proteolysis);GO:0005576(extracellular region);GO:0004181(metallocarboxypeptidase activity);GO:0004180(carboxypeptidase activity);GO:0008237(metallopeptidase activity);GO:0030449(regulation of complement activation);GO:0005794(Golgi apparatus);GO:0030141(secretory granule);GO:0043025(neuronal cell body);GO:0004185(serine-type carboxypeptidase activity);GO:0010815(bradykinin catabolic process);GO:0030070(insulin processing);GO:0051384(response to glucocorticoid);GO:0097060(synaptic membrane)","NA","NA","NA","carboxypeptidase N subunit 1 [Source:HGNC Symbol;Acc:HGNC:2312]",{"v":0.0919652623211447,"d":"0.09"},{"v":0.00956478219395866,"d":"0.01"},{"v":9.61498761354253,"d":"9.61"},{"v":3.26528499902203,"d":"3.27"},1,1,"up","no"]
["ENSG00000148057","IDNK","ENST00000454393;ENST00000405990;ENST00000376419;ENST00000533522;ENST00000376417","GO:0016301(kinase activity);GO:0005975(carbohydrate metabolic process);GO:0016310(phosphorylation);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0016740(transferase activity);GO:0003674(molecular_function);GO:0008150(biological_process);GO:0046316(gluconokinase activity);GO:0046177(D-gluconate catabolic process);GO:0046177(D-gluconate catabolic process)","00030(Pentose phosphate pathway);00030(Pentose phosphate pathway)","K00851","EC:2.7.1.12","IDNK, gluconokinase [Source:HGNC Symbol;Acc:HGNC:31367]",{"v":0.414439846747519,"d":"0.41"},{"v":0.411738666482911,"d":"0.41"},{"v":1.0065604240857,"d":"1.01"},{"v":0.00943378021972013,"d":"0.01"},1,1,"up","no"]
["MSTRG.11790","SEC24B-AS1","ENST00000505895;ENST00000499713;ENST00000499359","NA","NA","NA","NA","SEC24B antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:44003]",{"v":0.176080801857585,"d":"0.18"},{"v":0.0482603544891641,"d":"0.05"},{"v":3.6485600597302,"d":"3.65"},{"v":1.86732720246809,"d":"1.87"},1,1,"up","no"]
["ENSG00000173389","IQCF1","ENST00000314534","GO:0031410(cytoplasmic vesicle);GO:2000344(positive regulation of acrosome reaction);GO:0001669(acrosomal vesicle);GO:0005516(calmodulin binding);GO:0060474(positive regulation of flagellated sperm motility involved in capacitation)","NA","NA","NA","IQ motif containing F1 [Source:HGNC Symbol;Acc:HGNC:28607]",{"v":0.028288,"d":"0.03"},0,"inf","inf",1,1,"up","no"]
["ENSG00000279110","AL022323.4","ENST00000623980","NA","NA","NA","NA",null,{"v":0.010879,"d":"0.01"},0,"inf","inf",1,1,"up","no"]
["ENSG00000268209","AC114786.4","ENST00000508771","NA","NA","NA","NA",null,0,{"v":0.023501,"d":"0.02"},"-inf","-inf",1,1,"down","no"]
["MSTRG.6824","AC099811.6","ENST00000624554","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000218208","RPS27AP11","ENST00000402798","NA","NA","NA","NA","ribosomal protein S27a pseudogene 11 [Source:HGNC Symbol;Acc:HGNC:36126]",{"v":0.187823,"d":"0.19"},0,"inf","inf",1,1,"up","no"]
["ENSG00000235489","DBF4P1","ENST00000412976","NA","NA","NA","NA","DBF4 zinc finger pseudogene 1 [Source:HGNC Symbol;Acc:HGNC:45059]",{"v":0.093277,"d":"0.09"},0,"inf","inf",1,1,"up","no"]
["ENSG00000278737","AC013553.4","ENST00000619781","NA","NA","NA","NA",null,{"v":0.081538,"d":"0.08"},0,"inf","inf",1,1,"up","no"]
["ENSG00000270679","AC138473.1","ENST00000605717","NA","NA","NA","NA",null,{"v":0.094904,"d":"0.09"},0,"inf","inf",1,1,"up","no"]
["ENSG00000178928","TPRX1","ENST00000322175;ENST00000535759","GO:0005634(nucleus);GO:0003677(DNA binding);GO:0006355(regulation of transcription, DNA-templated);GO:0043565(sequence-specific DNA binding);GO:0043565(sequence-specific DNA binding)","NA","NA","NA","tetrapeptide repeat homeobox 1 [Source:HGNC Symbol;Acc:HGNC:32174]",{"v":0.0414109706024096,"d":"0.04"},{"v":0.0108437359036145,"d":"0.01"},{"v":3.81888409774036,"d":"3.82"},{"v":1.93315113516006,"d":"1.93"},1,1,"up","no"]
["MSTRG.13771","AC073850.1","ENST00000449243","NA","NA","NA","NA",null,0,{"v":0.52463,"d":"0.52"},"-inf","-inf",1,1,"down","no"]
["MSTRG.9732","AL109614.1","ENST00000620327","NA","NA","NA","NA",null,0,{"v":0.216323,"d":"0.22"},"-inf","-inf",1,1,"down","no"]
["ENSG00000278665","AC020765.3","ENST00000613051","NA","NA","NA","NA",null,{"v":0.022691,"d":"0.02"},{"v":0.092481,"d":"0.09"},{"v":0.245358506071517,"d":"0.25"},{"v":-2.02703680736353,"d":"-2.03"},1,1,"down","no"]
["ENSG00000253910","PCDHGB2","ENST00000622527","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005509(calcium ion binding);GO:0007155(cell adhesion);GO:0007156(homophilic cell adhesion via plasma membrane adhesion molecules);GO:0005886(plasma membrane);GO:0005887(integral component of plasma membrane);GO:0007399(nervous system development);GO:0007267(cell-cell signaling)","NA","NA","NA","protocadherin gamma subfamily B, 2 [Source:HGNC Symbol;Acc:HGNC:8709]",{"v":0.172453922415601,"d":"0.17"},{"v":0.124399825539945,"d":"0.12"},{"v":1.38628749411088,"d":"1.39"},{"v":0.471226480647629,"d":"0.47"},1,1,"up","no"]
["ENSG00000237285","HNRNPA1P2","ENST00000432375","NA","NA","NA","NA","heterogeneous nuclear ribonucleoprotein A1 pseudogene 2 [Source:HGNC Symbol;Acc:HGNC:13958]",{"v":0.200075,"d":"0.20"},0,"inf","inf",1,1,"up","no"]
["ENSG00000237604","AP001056.1","ENST00000411956","NA","NA","NA","NA",null,{"v":0.427829,"d":"0.43"},{"v":0.241893,"d":"0.24"},{"v":1.76867044519684,"d":"1.77"},{"v":0.82266525697564,"d":"0.82"},1,1,"up","no"]
["ENSG00000170370","EMX2","ENST00000553456","GO:0005634(nucleus);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0043565(sequence-specific DNA binding);GO:0005515(protein binding);GO:0007275(multicellular organism development);GO:0007420(brain development);GO:0009952(anterior/posterior pattern specification);GO:0010468(regulation of gene expression);GO:0021542(dentate gyrus development);GO:0021796(cerebral cortex regionalization);GO:0021846(cell proliferation in forebrain);GO:0021885(forebrain cell migration);GO:0021987(cerebral cortex development);GO:0030182(neuron differentiation);GO:0030900(forebrain development);GO:0042493(response to drug);GO:0072001(renal system development)","NA","NA","NA","empty spiracles homeobox 2 [Source:HGNC Symbol;Acc:HGNC:3341]",{"v":0.0116608246474555,"d":"0.01"},0,"inf","inf",1,1,"up","no"]
["ENSG00000270020","AC009108.3","ENST00000602739","NA","NA","NA","NA",null,{"v":0.014624,"d":"0.01"},{"v":0.024402,"d":"0.02"},{"v":0.599295139742644,"d":"0.60"},{"v":-0.738661421125219,"d":"-0.74"},1,1,"down","no"]
["MSTRG.7768","AC136469.1","ENST00000595706","NA","NA","NA","NA",null,0,{"v":0.121347,"d":"0.12"},"-inf","-inf",1,1,"down","no"]
["MSTRG.1273","LINC00862","ENST00000367355;ENST00000636153;ENST00000637098","NA","NA","NA","NA","long intergenic non-protein coding RNA 862 [Source:HGNC Symbol;Acc:HGNC:21901]",{"v":0.0480445144927536,"d":"0.05"},{"v":0.0359984625078765,"d":"0.04"},{"v":1.33462684641716,"d":"1.33"},{"v":0.416436429496578,"d":"0.42"},1,1,"up","no"]
["ENSG00000170128","GPR25","ENST00000304244","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0004930(G-protein coupled receptor activity);GO:0007186(G-protein coupled receptor signaling pathway);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0004871(signal transducer activity);GO:0007165(signal transduction);GO:0005887(integral component of plasma membrane)","NA","NA","NA","G protein-coupled receptor 25 [Source:HGNC Symbol;Acc:HGNC:4480]",{"v":0.540897,"d":"0.54"},0,"inf","inf",1,1,"up","no"]
["MSTRG.3563","AC084032.1","ENST00000552324","NA","NA","NA","NA",null,{"v":0.044169,"d":"0.04"},{"v":0.019558,"d":"0.02"},{"v":2.25835975048573,"d":"2.26"},{"v":1.17527532176241,"d":"1.18"},1,1,"up","no"]
["ENSG00000106025","TSPAN12","ENST00000222747","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0007166(cell surface receptor signaling pathway);GO:0010842(retina layer formation);GO:0045765(regulation of angiogenesis);GO:0005887(integral component of plasma membrane);GO:0001525(angiogenesis)","NA","NA","NA","tetraspanin 12 [Source:HGNC Symbol;Acc:HGNC:21641]",{"v":0.011192,"d":"0.01"},0,"inf","inf",1,1,"up","no"]
["ENSG00000082126","MPP4","ENST00000409474","GO:0005737(cytoplasm)","04530(Tight junction)","K21109","NA","membrane palmitoylated protein 4 [Source:HGNC Symbol;Acc:HGNC:13680]",{"v":0.012405,"d":"0.01"},{"v":0.0014765,"d":"0.00"},{"v":8.40162546562818,"d":"8.40"},{"v":3.07066847364584,"d":"3.07"},1,1,"up","no"]
["ENSG00000163209","SPRR3","ENST00000331860","GO:0005737(cytoplasm);GO:0005515(protein binding);GO:0031424(keratinization);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0008544(epidermis development);GO:0018149(peptide cross-linking);GO:0030216(keratinocyte differentiation);GO:0001533(cornified envelope);GO:0042060(wound healing);GO:0005198(structural molecule activity);GO:0070268(cornification)","NA","NA","NA","small proline rich protein 3 [Source:HGNC Symbol;Acc:HGNC:11268]",{"v":0.0354333414295628,"d":"0.04"},0,"inf","inf",1,1,"up","no"]
["ENSG00000160882","CYP11B1","ENST00000314111","GO:0046872(metal ion binding);GO:0004497(monooxygenase activity);GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0005506(iron ion binding);GO:0016705(oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen);GO:0020037(heme binding);GO:0016020(membrane);GO:0006629(lipid metabolic process);GO:0005739(mitochondrion);GO:0006694(steroid biosynthetic process);GO:0008202(steroid metabolic process);GO:0031966(mitochondrial membrane);GO:0005743(mitochondrial inner membrane);GO:0006955(immune response);GO:0032870(cellular response to hormone stimulus);GO:0008217(regulation of blood pressure);GO:0016125(sterol metabolic process);GO:0042593(glucose homeostasis);GO:0032342(aldosterone biosynthetic process);GO:0034651(cortisol biosynthetic process);GO:0035865(cellular response to potassium ion);GO:0006704(glucocorticoid biosynthetic process);GO:0004507(steroid 11-beta-monooxygenase activity);GO:0047783(corticosterone 18-monooxygenase activity);GO:0006700(C21-steroid hormone biosynthetic process)","00140(Steroid hormone biosynthesis);04927(Cortisol synthesis and secretion)","NA","NA","cytochrome P450 family 11 subfamily B member 1 [Source:HGNC Symbol;Acc:HGNC:2591]",{"v":0.0447049129814551,"d":"0.04"},{"v":0.0468319044222539,"d":"0.05"},{"v":0.954582426936538,"d":"0.95"},{"v":-0.0670583170609044,"d":"-0.07"},1,1,"down","no"]
["ENSG00000166589","CDH16","ENST00000567269","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0046872(metal ion binding);GO:0005509(calcium ion binding);GO:0007155(cell adhesion);GO:0007156(homophilic cell adhesion via plasma membrane adhesion molecules);GO:0005886(plasma membrane);GO:0005887(integral component of plasma membrane);GO:0016339(calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules);GO:0070062(extracellular exosome);GO:0007399(nervous system development);GO:0007267(cell-cell signaling);GO:0016323(basolateral plasma membrane)","NA","NA","NA","cadherin 16 [Source:HGNC Symbol;Acc:HGNC:1755]",{"v":0.0355148717177243,"d":"0.04"},{"v":0.0388515601750547,"d":"0.04"},{"v":0.914117002192546,"d":"0.91"},{"v":-0.12954926037006,"d":"-0.13"},1,1,"down","no"]
["MSTRG.9314","TMEFF2","ENST00000392314","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005576(extracellular region);GO:0003674(molecular_function);GO:0030336(negative regulation of cell migration);GO:0051497(negative regulation of stress fiber assembly);GO:0044319(wound healing, spreading of cells);GO:0045720(negative regulation of integrin biosynthetic process)","NA","NA","NA","transmembrane protein with EGF like and two follistatin like domains 2 [Source:HGNC Symbol;Acc:HGNC:11867]",0,{"v":0.0118569508443908,"d":"0.01"},"-inf","-inf",1,1,"down","no"]
["MSTRG.10592","AL671710.1","ENST00000610245","NA","NA","NA","NA",null,{"v":0.118697,"d":"0.12"},{"v":0.10709,"d":"0.11"},{"v":1.10838547016528,"d":"1.11"},{"v":0.148459703754154,"d":"0.15"},1,1,"up","no"]
["ENSG00000235733","AL024509.3","ENST00000413898","NA","NA","NA","NA",null,0,{"v":0.12248,"d":"0.12"},"-inf","-inf",1,1,"down","no"]
["MSTRG.11471","NCBP2-AS1","ENST00000447775","NA","NA","NA","NA","NCBP2 antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:40392]",{"v":0.383551,"d":"0.38"},{"v":0.092996,"d":"0.09"},{"v":4.12438169383629,"d":"4.12"},{"v":2.04417785412285,"d":"2.04"},1,1,"up","no"]
["ENSG00000189166","TNRC18P3","ENST00000441896","NA","NA","NA","NA","trinucleotide repeat containing 18 pseudogene 3 [Source:HGNC Symbol;Acc:HGNC:34015]",{"v":0.140824,"d":"0.14"},{"v":0.180563,"d":"0.18"},{"v":0.77991615114946,"d":"0.78"},{"v":-0.358609066839761,"d":"-0.36"},1,1,"down","no"]
["MSTRG.6679","AC079336.5","ENST00000581360","NA","NA","NA","NA",null,{"v":0.092303,"d":"0.09"},{"v":0.05519,"d":"0.06"},{"v":1.67245877876427,"d":"1.67"},{"v":0.74197065307586,"d":"0.74"},1,1,"up","no"]
["ENSG00000110328","GALNT18","ENST00000227756","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0046872(metal ion binding);GO:0016740(transferase activity);GO:0030246(carbohydrate binding);GO:0016757(transferase activity, transferring glycosyl groups);GO:0005794(Golgi apparatus);GO:0000139(Golgi membrane);GO:0006486(protein glycosylation);GO:0004653(polypeptide N-acetylgalactosaminyltransferase activity)","00512(Mucin type O-glycan biosynthesis)","K00710","EC:2.4.1.41","polypeptide N-acetylgalactosaminyltransferase 18 [Source:HGNC Symbol;Acc:HGNC:30488]",{"v":0.027104229390681,"d":"0.03"},{"v":0.014322576233802,"d":"0.01"},{"v":1.8924129952762,"d":"1.89"},{"v":0.920226973041143,"d":"0.92"},1,1,"up","no"]
["MSTRG.14605","AC105202.1","ENST00000518831;ENST00000517833;ENST00000518024;ENST00000502167","NA","NA","NA","NA",null,{"v":0.0263702146379445,"d":"0.03"},{"v":0.0221823280560602,"d":"0.02"},{"v":1.1887938259366,"d":"1.19"},{"v":0.249498528295855,"d":"0.25"},1,1,"up","no"]
["MSTRG.5075","AC026770.1","ENST00000558994","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000144452","ABCA12","ENST00000272895","GO:0005737(cytoplasm);GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005215(transporter activity);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0006869(lipid transport);GO:0005515(protein binding);GO:0016887(ATPase activity);GO:0005886(plasma membrane);GO:0042626(ATPase activity, coupled to transmembrane movement of substances);GO:0055085(transmembrane transport);GO:0005102(receptor binding);GO:0043231(intracellular membrane-bounded organelle);GO:0005319(lipid transporter activity);GO:0010875(positive regulation of cholesterol efflux);GO:0033700(phospholipid efflux);GO:0034191(apolipoprotein A-I receptor binding);GO:0072659(protein localization to plasma membrane);GO:0032940(secretion by cell);GO:0019725(cellular homeostasis);GO:0034040(lipid-transporting ATPase activity);GO:0030216(keratinocyte differentiation);GO:0031424(keratinization);GO:0035627(ceramide transport);GO:0043129(surfactant homeostasis);GO:0045055(regulated exocytosis);GO:0048286(lung alveolus development);GO:0055088(lipid homeostasis);GO:0061436(establishment of skin barrier);GO:2000010(positive regulation of protein localization to cell surface);GO:0005743(mitochondrial inner membrane);GO:0005829(cytosol);GO:0097209(epidermal lamellar body)","02010(ABC transporters)","K05646","NA","ATP binding cassette subfamily A member 12 [Source:HGNC Symbol;Acc:HGNC:14637]",{"v":0.012975424808836,"d":"0.01"},{"v":0.00710526762956669,"d":"0.01"},{"v":1.82616974972796,"d":"1.83"},{"v":0.868820875786699,"d":"0.87"},1,1,"up","no"]
["MSTRG.14516","AC087620.1","ENST00000520037","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000169750","RAC3","ENST00000306897;ENST00000580965;ENST00000585014;ENST00000584341","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005525(GTP binding);GO:0007264(small GTPase mediated signal transduction);GO:0000166(nucleotide binding);GO:0003924(GTPase activity);GO:0005622(intracellular);GO:0005886(plasma membrane);GO:0005856(cytoskeleton);GO:0042995(cell projection);GO:0005515(protein binding);GO:0048471(perinuclear region of cytoplasm);GO:0005829(cytosol);GO:0030027(lamellipodium);GO:0070062(extracellular exosome);GO:0051056(regulation of small GTPase mediated signal transduction);GO:0071944(cell periphery);GO:0048306(calcium-dependent protein binding);GO:0012505(endomembrane system);GO:0030036(actin cytoskeleton organization);GO:0035556(intracellular signal transduction);GO:1900026(positive regulation of substrate adhesion-dependent cell spreading);GO:0030031(cell projection assembly);GO:0043025(neuronal cell body);GO:0033630(positive regulation of cell adhesion mediated by integrin);GO:0043005(neuron projection);GO:0014041(regulation of neuron maturation);GO:0021894(cerebral cortex GABAergic interneuron development);GO:0022604(regulation of cell morphogenesis);GO:0031175(neuron projection development);GO:0048873(homeostasis of number of cells within a tissue);GO:0050885(neuromuscular process controlling balance);GO:0050905(neuromuscular process);GO:0051932(synaptic transmission, GABAergic);GO:0030426(growth cone);GO:0031941(filamentous actin);GO:0031941(filamentous actin)","04014(Ras signaling pathway);04015(Rap1 signaling pathway);04010(MAPK signaling pathway);04310(Wnt signaling pathway);04370(VEGF signaling pathway);04071(Sphingolipid signaling pathway);04024(cAMP signaling pathway);04510(Focal adhesion);04520(Adherens junction);04810(Regulation of actin cytoskeleton);04650(Natural killer cell mediated cytotoxicity);04662(B cell receptor signaling pathway);04664(Fc epsilon RI signaling pathway);04360(Axon guidance);05200(Pathways in cancer);05231(Choline metabolism in cancer);05210(Colorectal cancer);05212(Pancreatic cancer);05418(Fluid shear stress and atherosclerosis);05416(Viral myocarditis);05416(Viral myocarditis)","K07861","NA","ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3) [Source:HGNC Symbol;Acc:HGNC:9803]",{"v":4.26383104125737E-3,"d":"0.00"},{"v":0.1628501702685,"d":"0.16"},{"v":0.0261825396573265,"d":"0.03"},{"v":-5.25525114698636,"d":"-5.26"},1,1,"down","no"]
["ENSG00000226435","ANKRD18DP","ENST00000440713;ENST00000435620","NA","NA","NA","NA","ankyrin repeat domain 18D, pseudogene [Source:HGNC Symbol;Acc:HGNC:28016]",{"v":0.0130654783995361,"d":"0.01"},0,"inf","inf",1,1,"up","no"]
["ENSG00000127533","F2RL3","ENST00000248076","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0004930(G-protein coupled receptor activity);GO:0007186(G-protein coupled receptor signaling pathway);GO:0005886(plasma membrane);GO:0004871(signal transducer activity);GO:0007165(signal transduction);GO:0007596(blood coagulation);GO:0015057(thrombin-activated receptor activity);GO:0070493(thrombin-activated receptor signaling pathway);GO:0005576(extracellular region);GO:0005887(integral component of plasma membrane);GO:0007599(hemostasis);GO:0009611(response to wounding);GO:0030168(platelet activation);GO:0035025(positive regulation of Rho protein signal transduction);GO:0051482(positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway);GO:0051281(positive regulation of release of sequestered calcium ion into cytosol);GO:0060155(platelet dense granule organization);GO:0007200(phospholipase C-activating G-protein coupled receptor signaling pathway)","04015(Rap1 signaling pathway);04080(Neuroactive ligand-receptor interaction);04610(Complement and coagulation cascades);04611(Platelet activation);05200(Pathways in cancer)","K04236","NA","F2R like thrombin or trypsin receptor 3 [Source:HGNC Symbol;Acc:HGNC:3540]",{"v":0.63272,"d":"0.63"},{"v":0.031791,"d":"0.03"},{"v":19.9024881255701,"d":"19.90"},{"v":4.31487689661272,"d":"4.31"},1,1,"up","no"]
["ENSG00000186352","ANKRD37","ENST00000507753;ENST00000511393;ENST00000511311;ENST00000335174;ENST00000507479","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005739(mitochondrion);GO:0005739(mitochondrion)","NA","NA","NA","ankyrin repeat domain 37 [Source:HGNC Symbol;Acc:HGNC:29593]",{"v":0.472151389147287,"d":"0.47"},{"v":0.241816817054264,"d":"0.24"},{"v":1.95251676413115,"d":"1.95"},{"v":0.965334935268691,"d":"0.97"},1,1,"up","no"]
["ENSG00000172748","ZNF596","ENST00000521270;ENST00000522866;ENST00000523418;ENST00000398612;ENST00000308811;ENST00000523162;ENST00000523333;ENST00000521145","GO:0003676(nucleic acid binding);GO:0006355(regulation of transcription, DNA-templated);GO:0005622(intracellular);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0003677(DNA binding)","NA","NA","NA","zinc finger protein 596 [Source:HGNC Symbol;Acc:HGNC:27268]",{"v":0.0837272691411451,"d":"0.08"},{"v":0.057488396804261,"d":"0.06"},{"v":1.45642031775948,"d":"1.46"},{"v":0.542426772320765,"d":"0.54"},1,1,"up","no"]
["MSTRG.4070","AL139035.1","ENST00000627052","NA","NA","NA","NA",null,0,{"v":0.178752565770863,"d":"0.18"},"-inf","-inf",1,1,"down","no"]
["ENSG00000255410","AC091564.6","ENST00000526633","NA","NA","NA","NA",null,0,{"v":0.016238,"d":"0.02"},"-inf","-inf",1,1,"down","no"]
["ENSG00000262468","LINC01569","ENST00000571970;ENST00000573268;ENST00000573042","NA","NA","NA","NA","long intergenic non-protein coding RNA 1569 [Source:HGNC Symbol;Acc:HGNC:51380]",{"v":0.345246343171806,"d":"0.35"},{"v":0.267177443171806,"d":"0.27"},{"v":1.29219869414574,"d":"1.29"},{"v":0.369827922213662,"d":"0.37"},1,1,"up","no"]
["ENSG00000216613","AL023284.2","ENST00000405850","NA","NA","NA","NA",null,0,{"v":0.052532,"d":"0.05"},"-inf","-inf",1,1,"down","no"]
["ENSG00000181408","UTS2R","ENST00000313135","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0004930(G-protein coupled receptor activity);GO:0007186(G-protein coupled receptor signaling pathway);GO:0005886(plasma membrane);GO:0004871(signal transducer activity);GO:0007165(signal transduction);GO:0008217(regulation of blood pressure);GO:0005887(integral component of plasma membrane);GO:0007200(phospholipase C-activating G-protein coupled receptor signaling pathway);GO:0007218(neuropeptide signaling pathway);GO:0097746(regulation of blood vessel diameter);GO:0008015(blood circulation);GO:0001604(urotensin II receptor activity);GO:0003105(negative regulation of glomerular filtration);GO:0007204(positive regulation of cytosolic calcium ion concentration);GO:0010841(positive regulation of circadian sleep/wake cycle, wakefulness);GO:0030307(positive regulation of cell growth);GO:0035811(negative regulation of urine volume);GO:0035814(negative regulation of renal sodium excretion);GO:0042493(response to drug);GO:0045766(positive regulation of angiogenesis);GO:0045776(negative regulation of blood pressure);GO:0045777(positive regulation of blood pressure);GO:0045907(positive regulation of vasoconstriction);GO:0046005(positive regulation of circadian sleep/wake cycle, REM sleep);GO:0048146(positive regulation of fibroblast proliferation);GO:0005769(early endosome);GO:0055037(recycling endosome)","04080(Neuroactive ligand-receptor interaction)","K04241","NA","urotensin 2 receptor [Source:HGNC Symbol;Acc:HGNC:4468]",0,{"v":0.033621,"d":"0.03"},"-inf","-inf",1,1,"down","no"]
["ENSG00000174562","KLK15","ENST00000596531","GO:0016787(hydrolase activity);GO:0005515(protein binding);GO:0008233(peptidase activity);GO:0006508(proteolysis);GO:0005576(extracellular region);GO:0004252(serine-type endopeptidase activity);GO:0008236(serine-type peptidase activity)","NA","NA","NA","kallikrein related peptidase 15 [Source:HGNC Symbol;Acc:HGNC:20453]",{"v":0.0414690196592398,"d":"0.04"},0,"inf","inf",1,1,"up","no"]
["ENSG00000269646","AC010487.2","ENST00000594546","NA","NA","NA","NA",null,{"v":0.098581,"d":"0.10"},0,"inf","inf",1,1,"up","no"]
["ENSG00000213062","AL021068.1","ENST00000392097","NA","NA","NA","NA",null,0,{"v":0.095655,"d":"0.10"},"-inf","-inf",1,1,"down","no"]
["ENSG00000262587","AC133552.2","ENST00000619106","NA","NA","NA","NA",null,{"v":0.43261055062167,"d":"0.43"},0,"inf","inf",1,1,"up","no"]
["ENSG00000188396","TCTEX1D4","ENST00000339355","GO:0005515(protein binding);GO:0008157(protein phosphatase 1 binding);GO:0001669(acrosomal vesicle);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005815(microtubule organizing center);GO:0005930(axoneme);GO:0036126(sperm flagellum)","NA","NA","NA","Tctex1 domain containing 4 [Source:HGNC Symbol;Acc:HGNC:32315]",{"v":0.066695,"d":"0.07"},0,"inf","inf",1,1,"up","no"]
["ENSG00000179284","DAND5","ENST00000317060","GO:0030512(negative regulation of transforming growth factor beta receptor signaling pathway);GO:0030514(negative regulation of BMP signaling pathway);GO:0005576(extracellular region);GO:0005615(extracellular space);GO:0016015(morphogen activity);GO:0023019(signal transduction involved in regulation of gene expression);GO:0061371(determination of heart left/right asymmetry);GO:1900176(negative regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry);GO:0003281(ventricular septum development);GO:0003283(atrial septum development);GO:0003140(determination of left/right asymmetry in lateral mesoderm);GO:0007368(determination of left/right symmetry);GO:0017015(regulation of transforming growth factor beta receptor signaling pathway);GO:0035582(sequestering of BMP in extracellular matrix);GO:0038101(sequestering of nodal from receptor via nodal binding);GO:1900108(negative regulation of nodal signaling pathway)","NA","NA","NA","DAN domain BMP antagonist family member 5 [Source:HGNC Symbol;Acc:HGNC:26780]",{"v":0.124612309964947,"d":"0.12"},{"v":0.0228463890836254,"d":"0.02"},{"v":5.45435471263421,"d":"5.45"},{"v":2.4474085259807,"d":"2.45"},1,1,"up","no"]
["ENSG00000249272","UNC93B8","ENST00000511903","NA","NA","NA","NA","unc-93 homolog B8 pseudogene (C. elegans) [Source:HGNC Symbol;Acc:HGNC:44037]",0,{"v":0.064715,"d":"0.06"},"-inf","-inf",1,1,"down","no"]
["ENSG00000251209","LINC00923","ENST00000503768","NA","NA","NA","NA","long intergenic non-protein coding RNA 923 [Source:HGNC Symbol;Acc:HGNC:28088]",{"v":0.0110567631748763,"d":"0.01"},0,"inf","inf",1,1,"up","no"]
["ENSG00000234413","AC245102.1","ENST00000454989","NA","NA","NA","NA",null,0,{"v":0.085983,"d":"0.09"},"-inf","-inf",1,1,"down","no"]
["MSTRG.10896","MIR1226","ENST00000408658","NA","NA","NA","NA","microRNA 1226 [Source:HGNC Symbol;Acc:HGNC:33922]",{"v":0.006854,"d":"0.01"},{"v":0.004056,"d":"0.00"},{"v":1.68984220907298,"d":"1.69"},{"v":0.756888539515834,"d":"0.76"},1,1,"up","no"]
["ENSG00000227367","SLC9B1P4","ENST00000421957","NA","NA","NA","NA","solute carrier family 9 member B1 pseudogene 4 [Source:HGNC Symbol;Acc:HGNC:43583]",0,{"v":0.01594,"d":"0.02"},"-inf","-inf",1,1,"down","no"]
["ENSG00000181577","C6orf223","ENST00000336600","NA","NA","NA","NA","chromosome 6 open reading frame 223 [Source:HGNC Symbol;Acc:HGNC:28692]",0,{"v":0.0116471636456472,"d":"0.01"},"-inf","-inf",1,1,"down","no"]
["ENSG00000141437","SLC25A52","ENST00000269205","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane)","NA","NA","NA","solute carrier family 25 member 52 [Source:HGNC Symbol;Acc:HGNC:23324]",{"v":0.077941,"d":"0.08"},0,"inf","inf",1,1,"up","no"]
["ENSG00000182327","GLTPD2","ENST00000331264","GO:0005737(cytoplasm);GO:0120013(intermembrane lipid transfer activity);GO:0120009(intermembrane lipid transfer)","NA","NA","NA","glycolipid transfer protein domain containing 2 [Source:HGNC Symbol;Acc:HGNC:33756]",{"v":0.149064,"d":"0.15"},{"v":0.061029,"d":"0.06"},{"v":2.44251093742319,"d":"2.44"},{"v":1.28836502251336,"d":"1.29"},1,1,"up","no"]
["ENSG00000267586","LINC00907","ENST00000591199;ENST00000593234","NA","NA","NA","NA","long intergenic non-protein coding RNA 907 [Source:HGNC Symbol;Acc:HGNC:44327]",{"v":0.0261123179455824,"d":"0.03"},0,"inf","inf",1,1,"up","no"]
["ENSG00000224789","AC012363.1","ENST00000455707","NA","NA","NA","NA",null,{"v":0.008939,"d":"0.01"},0,"inf","inf",1,1,"up","no"]
["ENSG00000261654","AL360270.2","ENST00000562952","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000107984","DKK1","ENST00000373970","GO:0005615(extracellular space);GO:2000726(negative regulation of cardiac muscle cell differentiation);GO:0090090(negative regulation of canonical Wnt signaling pathway);GO:0005576(extracellular region);GO:0007275(multicellular organism development);GO:0005515(protein binding);GO:0016055(Wnt signaling pathway);GO:0030178(negative regulation of Wnt signaling pathway);GO:0005886(plasma membrane);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0000904(cell morphogenesis involved in differentiation);GO:0001706(endoderm formation);GO:0001707(mesoderm formation);GO:0001942(hair follicle development);GO:0007492(endoderm development);GO:0007611(learning or memory);GO:0010628(positive regulation of gene expression);GO:0030111(regulation of Wnt signaling pathway);GO:0030279(negative regulation of ossification);GO:0030326(embryonic limb morphogenesis);GO:0030514(negative regulation of BMP signaling pathway);GO:0030900(forebrain development);GO:0032526(response to retinoic acid);GO:0043066(negative regulation of apoptotic process);GO:0048642(negative regulation of skeletal muscle tissue development);GO:0050807(regulation of synapse organization);GO:0051966(regulation of synaptic transmission, glutamatergic);GO:0060173(limb development);GO:0060323(head morphogenesis);GO:0060325(face morphogenesis);GO:0061743(motor learning);GO:0090082(positive regulation of heart induction by negative regulation of canonical Wnt signaling pathway);GO:0090244(Wnt signaling pathway involved in somitogenesis);GO:0090647(modulation of age-related behavioral decline);GO:1902949(positive regulation of tau-protein kinase activity);GO:1904958(positive regulation of midbrain dopaminergic neuron differentiation);GO:0004871(signal transducer activity);GO:0008083(growth factor activity);GO:0033137(negative regulation of peptidyl-serine phosphorylation);GO:0060394(negative regulation of pathway-restricted SMAD protein phosphorylation);GO:0050750(low-density lipoprotein particle receptor binding);GO:0010942(positive regulation of cell death);GO:0031901(early endosome membrane);GO:0039706(co-receptor binding);GO:0048019(receptor antagonist activity);GO:0002090(regulation of receptor internalization);GO:0032091(negative regulation of protein binding);GO:0042662(negative regulation of mesodermal cell fate specification);GO:0042663(regulation of endodermal cell fate specification);GO:0043507(positive regulation of JUN kinase activity);GO:0045813(positive regulation of Wnt signaling pathway, calcium modulating pathway);GO:0098883(synapse disassembly);GO:1900116(extracellular negative regulation of signal transduction);GO:1901216(positive regulation of neuron death);GO:1901296(negative regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment);GO:1904338(regulation of dopaminergic neuron differentiation);GO:1904723(negative regulation of Wnt-Frizzled-LRP5/6 complex assembly);GO:2000096(positive regulation of Wnt signaling pathway, planar cell polarity pathway)","04310(Wnt signaling pathway)","K02165","NA","dickkopf WNT signaling pathway inhibitor 1 [Source:HGNC Symbol;Acc:HGNC:2891]",0,{"v":0.00234420217588395,"d":"0.00"},"-inf","-inf",1,1,"down","no"]
["ENSG00000255186","AC087277.2","ENST00000533203","NA","NA","NA","NA",null,{"v":0.04428,"d":"0.04"},0,"inf","inf",1,1,"up","no"]
["MSTRG.6662","AC116407.1","ENST00000398832","NA","NA","NA","NA",null,{"v":0.062793,"d":"0.06"},{"v":0.048327,"d":"0.05"},{"v":1.29933577503259,"d":"1.30"},{"v":0.377774300975801,"d":"0.38"},1,1,"up","no"]
["ENSG00000260012","AC007494.1","ENST00000562293","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000109654","TRIM2","ENST00000632856;ENST00000441616;ENST00000338700;ENST00000437508;ENST00000496978","GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0005622(intracellular);GO:0005737(cytoplasm);GO:0016740(transferase activity);GO:0016567(protein ubiquitination);GO:0005515(protein binding);GO:0004842(ubiquitin-protein transferase activity);GO:0043523(regulation of neuron apoptotic process);GO:0043523(regulation of neuron apoptotic process)","NA","NA","NA","tripartite motif containing 2 [Source:HGNC Symbol;Acc:HGNC:15974]",{"v":0.113186028116711,"d":"0.11"},{"v":0.0665043279575597,"d":"0.07"},{"v":1.70193477015423,"d":"1.70"},{"v":0.767175744087098,"d":"0.77"},1,1,"up","no"]
["ENSG00000175003","SLC22A1","ENST00000366963;ENST00000460902","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005215(transporter activity);GO:0055085(transmembrane transport);GO:0006811(ion transport);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0022857(transmembrane transporter activity);GO:0015711(organic anion transport);GO:0072488(ammonium transmembrane transport);GO:0005887(integral component of plasma membrane);GO:0008514(organic anion transmembrane transporter activity);GO:0016323(basolateral plasma membrane);GO:0005277(acetylcholine transmembrane transporter activity);GO:0005329(dopamine transmembrane transporter activity);GO:0005333(norepinephrine transmembrane transporter activity);GO:0008513(secondary active organic cation transmembrane transporter activity);GO:0015101(organic cation transmembrane transporter activity);GO:0015651(quaternary ammonium group transmembrane transporter activity);GO:0006836(neurotransmitter transport);GO:0006855(drug transmembrane transport);GO:0015872(dopamine transport);GO:0015874(norepinephrine transport);GO:1901374(acetate ester transport);GO:0008504(monoamine transmembrane transporter activity);GO:0042802(identical protein binding);GO:0042803(protein homodimerization activity);GO:0006812(cation transport);GO:0010248(establishment or maintenance of transmembrane electrochemical gradient);GO:0015695(organic cation transport);GO:0015697(quaternary ammonium group transport);GO:0015844(monoamine transport);GO:0048241(epinephrine transport);GO:0051260(protein homooligomerization);GO:0051260(protein homooligomerization)","04976(Bile secretion);05231(Choline metabolism in cancer);05231(Choline metabolism in cancer)","K08198","NA","solute carrier family 22 member 1 [Source:HGNC Symbol;Acc:HGNC:10963]",{"v":0.0501719532871972,"d":"0.05"},{"v":0.35542658650519,"d":"0.36"},{"v":0.141159820880379,"d":"0.14"},{"v":-2.82459859031133,"d":"-2.82"},1,1,"down","no"]
["ENSG00000230649","AC024084.1","ENST00000440744","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000151014","NOCT","ENST00000280614;ENST00000515616;ENST00000630479","GO:0003723(RNA binding);GO:0006397(mRNA processing);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0016787(hydrolase activity);GO:0090305(nucleic acid phosphodiester bond hydrolysis);GO:0007623(circadian rhythm);GO:0048511(rhythmic process);GO:0004527(exonuclease activity);GO:0048471(perinuclear region of cytoplasm);GO:0004518(nuclease activity);GO:0006355(regulation of transcription, DNA-templated);GO:0003729(mRNA binding);GO:0005654(nucleoplasm);GO:0004535(poly(A)-specific ribonuclease activity);GO:0090503(RNA phosphodiester bond hydrolysis, exonucleolytic);GO:0032496(response to lipopolysaccharide);GO:0010629(negative regulation of gene expression);GO:0006366(transcription from RNA polymerase II promoter);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0032922(circadian regulation of gene expression);GO:0042752(regulation of circadian rhythm);GO:0045600(positive regulation of fat cell differentiation);GO:0045668(negative regulation of osteoblast differentiation);GO:0048255(mRNA stabilization);GO:0009991(response to extracellular stimulus);GO:0000290(deadenylation-dependent decapping of nuclear-transcribed mRNA);GO:0033962(cytoplasmic mRNA processing body assembly);GO:0045995(regulation of embryonic development);GO:0000932(P-body);GO:0000932(P-body)","NA","NA","NA","nocturnin [Source:HGNC Symbol;Acc:HGNC:14254]",{"v":0.195802319089457,"d":"0.20"},{"v":0.222348110223642,"d":"0.22"},{"v":0.880611572963293,"d":"0.88"},{"v":-0.183422290645443,"d":"-0.18"},1,1,"down","no"]
["ENSG00000106526","ACTR3C","ENST00000477871;ENST00000478393;ENST00000613959;ENST00000252071","GO:0005524(ATP binding);GO:0007015(actin filament organization);GO:0034314(Arp2/3 complex-mediated actin nucleation);GO:0005885(Arp2/3 protein complex);GO:0000166(nucleotide binding);GO:0003779(actin binding);GO:0003674(molecular_function);GO:0008150(biological_process);GO:0070062(extracellular exosome);GO:0070062(extracellular exosome)","04530(Tight junction);04530(Tight junction)","K18584","NA","ARP3 actin related protein 3 homolog C [Source:HGNC Symbol;Acc:HGNC:37282]",{"v":0.080789440866873,"d":"0.08"},{"v":0.0937181865325077,"d":"0.09"},{"v":0.862046565944272,"d":"0.86"},{"v":-0.214162292113164,"d":"-0.21"},1,1,"down","no"]
["ENSG00000279400","AC008957.3","ENST00000624112","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000236483","MTND2P40","ENST00000436718","NA","NA","NA","NA","mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 2 pseudogene 40 [Source:HGNC Symbol;Acc:HGNC:52084]",{"v":0.117323,"d":"0.12"},0,"inf","inf",1,1,"up","no"]
["ENSG00000213438","YBX2P1","ENST00000394192","NA","NA","NA","NA","Y-box binding protein 2 pseudogene 1 [Source:HGNC Symbol;Acc:HGNC:49498]",0,0,1,0,1,1,"no","no"]
["ENSG00000172680","MOS","ENST00000311923","GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0000165(MAPK cascade);GO:0016310(phosphorylation);GO:0005515(protein binding);GO:0004709(MAP kinase kinase kinase activity);GO:0005737(cytoplasm);GO:0006325(chromatin organization);GO:0035556(intracellular signal transduction);GO:0004871(signal transducer activity);GO:0046777(protein autophosphorylation);GO:0000187(activation of MAPK activity);GO:0000186(activation of MAPKK activity);GO:0000212(meiotic spindle organization);GO:0043410(positive regulation of MAPK cascade);GO:0051296(establishment of meiotic spindle orientation);GO:1902103(negative regulation of metaphase/anaphase transition of meiotic cell cycle)","04114(Oocyte meiosis);04810(Regulation of actin cytoskeleton);04914(Progesterone-mediated oocyte maturation)","K04367","EC:2.7.11.1","MOS proto-oncogene, serine/threonine kinase [Source:HGNC Symbol;Acc:HGNC:7199]",{"v":0.024689,"d":"0.02"},0,"inf","inf",1,1,"up","no"]
["ENSG00000162105","SHANK2","ENST00000468619;ENST00000601538;ENST00000425049;ENST00000449833;ENST00000409161;ENST00000606715","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005886(plasma membrane);GO:0042995(cell projection);GO:0005515(protein binding);GO:0030054(cell junction);GO:0045202(synapse);GO:0045211(postsynaptic membrane);GO:0005575(cellular_component);GO:0005829(cytosol);GO:0030426(growth cone);GO:0014069(postsynaptic density);GO:0043197(dendritic spine);GO:0017124(SH3 domain binding);GO:0016324(apical plasma membrane);GO:0060170(ciliary membrane);GO:0008328(ionotropic glutamate receptor complex);GO:0043025(neuronal cell body);GO:0031526(brush border membrane);GO:0007612(learning);GO:0043005(neuron projection);GO:0001917(photoreceptor inner segment);GO:0005883(neurofilament);GO:0007416(synapse assembly);GO:0035176(social behavior);GO:0030534(adult behavior);GO:0071625(vocalization behavior);GO:0035255(ionotropic glutamate receptor binding);GO:0030160(GKAP/Homer scaffold activity);GO:0060291(long-term synaptic potentiation);GO:0060292(long term synaptic depression);GO:0001750(photoreceptor outer segment);GO:0008022(protein C-terminus binding);GO:0007420(brain development);GO:0007584(response to nutrient);GO:0007613(memory);GO:0035640(exploration behavior);GO:0051968(positive regulation of synaptic transmission, glutamatergic);GO:0048786(presynaptic active zone);GO:0048786(presynaptic active zone)","04724(Glutamatergic synapse);04724(Glutamatergic synapse)","K15009","NA","SH3 and multiple ankyrin repeat domains 2 [Source:HGNC Symbol;Acc:HGNC:14295]",{"v":0.0196300693399269,"d":"0.02"},{"v":0.0145770222532789,"d":"0.01"},{"v":1.34664467124014,"d":"1.35"},{"v":0.429369228182698,"d":"0.43"},1,1,"up","no"]
["ENSG00000268764","AC011465.1","ENST00000599092","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000166006","KCNC2","ENST00000393288","GO:0005622(intracellular);GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0055085(transmembrane transport);GO:0005216(ion channel activity);GO:0006811(ion transport);GO:0005244(voltage-gated ion channel activity);GO:0005249(voltage-gated potassium channel activity);GO:0005267(potassium channel activity);GO:0006813(potassium ion transport);GO:0034765(regulation of ion transmembrane transport);GO:0051260(protein homooligomerization);GO:0071805(potassium ion transmembrane transport);GO:0008076(voltage-gated potassium channel complex);GO:0005886(plasma membrane);GO:0042995(cell projection);GO:0030054(cell junction);GO:0045202(synapse);GO:0045211(postsynaptic membrane);GO:0030425(dendrite);GO:0005887(integral component of plasma membrane);GO:0030424(axon);GO:0043204(perikaryon);GO:0051291(protein heterooligomerization);GO:0016323(basolateral plasma membrane);GO:0043005(neuron projection);GO:0016324(apical plasma membrane);GO:0042734(presynaptic membrane);GO:0050796(regulation of insulin secretion);GO:0005251(delayed rectifier potassium channel activity);GO:0032809(neuronal cell body membrane);GO:0071732(cellular response to nitric oxide);GO:0038060(nitric oxide-cGMP-mediated signaling pathway);GO:0044325(ion channel binding);GO:0009636(response to toxic substance);GO:0009642(response to light intensity);GO:0014070(response to organic cyclic compound);GO:0014075(response to amine);GO:0021759(globus pallidus development);GO:0032026(response to magnesium ion);GO:0034220(ion transmembrane transport);GO:0045471(response to ethanol);GO:0071242(cellular response to ammonium ion);GO:0097237(cellular response to toxic substance);GO:1901381(positive regulation of potassium ion transmembrane transport);GO:1903818(positive regulation of voltage-gated potassium channel activity);GO:1990089(response to nerve growth factor);GO:0030673(axolemma);GO:0031982(vesicle);GO:0043025(neuronal cell body);GO:0043195(terminal bouton)","NA","NA","NA","potassium voltage-gated channel subfamily C member 2 [Source:HGNC Symbol;Acc:HGNC:6234]",{"v":0.0161439148869347,"d":"0.02"},{"v":0.0160444056218593,"d":"0.02"},{"v":1.00620211601605,"d":"1.01"},{"v":0.0089201286882072,"d":"0.01"},1,1,"up","no"]
["ENSG00000233037","AC009237.5","ENST00000414271","NA","NA","NA","NA",null,{"v":0.0171,"d":"0.02"},0,"inf","inf",1,1,"up","no"]
["MSTRG.9050","AC068491.4","ENST00000622940","NA","NA","NA","NA",null,{"v":0.091195,"d":"0.09"},{"v":0.190909,"d":"0.19"},{"v":0.477688322708725,"d":"0.48"},{"v":-1.06585848493212,"d":"-1.07"},1,1,"down","no"]
["MSTRG.748","AL359258.2;AL359258.3","ENST00000564063;ENST00000622910","NA","NA","NA","NA",null,{"v":0.0724760674237048,"d":"0.07"},0,"inf","inf",1,1,"up","no"]
["ENSG00000251599","AC116345.3","ENST00000508255","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000250799","PRODH2","ENST00000587695","GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0004657(proline dehydrogenase activity);GO:0006560(proline metabolic process);GO:0006562(proline catabolic process);GO:0005739(mitochondrion);GO:0005743(mitochondrial inner membrane);GO:0010133(proline catabolic process to glutamate);GO:0046487(glyoxylate metabolic process);GO:0071949(FAD binding);GO:0016645(oxidoreductase activity, acting on the CH-NH group of donors)","00330(Arginine and proline metabolism)","NA","NA","proline dehydrogenase 2 [Source:HGNC Symbol;Acc:HGNC:17325]",{"v":0.0753486151592823,"d":"0.08"},{"v":0.0348427272061516,"d":"0.03"},{"v":2.16253494491038,"d":"2.16"},{"v":1.11272344578593,"d":"1.11"},1,1,"up","no"]
["MSTRG.14257","MIR6842","ENST00000612539","NA","NA","NA","NA","microRNA 6842 [Source:HGNC Symbol;Acc:HGNC:50254]",{"v":0.01318,"d":"0.01"},{"v":0.026906,"d":"0.03"},{"v":0.48985356426076,"d":"0.49"},{"v":-1.02957755726927,"d":"-1.03"},1,1,"down","no"]
["ENSG00000170953","OR8B12","ENST00000306842","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0004930(G-protein coupled receptor activity);GO:0007186(G-protein coupled receptor signaling pathway);GO:0005886(plasma membrane);GO:0004871(signal transducer activity);GO:0007165(signal transduction);GO:0004984(olfactory receptor activity);GO:0007608(sensory perception of smell);GO:0050896(response to stimulus);GO:0050911(detection of chemical stimulus involved in sensory perception of smell);GO:0005549(odorant binding)","04740(Olfactory transduction)","K04257","NA","olfactory receptor family 8 subfamily B member 12 [Source:HGNC Symbol;Acc:HGNC:15307]",{"v":0.0239413088029809,"d":"0.02"},0,"inf","inf",1,1,"up","no"]
["MSTRG.3202","TAS2R42","ENST00000334266","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0004930(G-protein coupled receptor activity);GO:0007186(G-protein coupled receptor signaling pathway);GO:0004871(signal transducer activity);GO:0007165(signal transduction);GO:0050896(response to stimulus);GO:0005886(plasma membrane);GO:0050909(sensory perception of taste)","04742(Taste transduction)","K08474","NA","taste 2 receptor member 42 [Source:HGNC Symbol;Acc:HGNC:18888]",{"v":0.046235,"d":"0.05"},{"v":0.047957,"d":"0.05"},{"v":0.964092833163042,"d":"0.96"},{"v":-0.0527560236441169,"d":"-0.05"},1,1,"down","no"]
["ENSG00000086289","EPDR1","ENST00000199448;ENST00000423717;ENST00000476620;ENST00000425345","GO:0005509(calcium ion binding);GO:0005576(extracellular region);GO:0007160(cell-matrix adhesion);GO:0070062(extracellular exosome);GO:0005615(extracellular space);GO:0005764(lysosome);GO:0005764(lysosome)","NA","NA","NA","ependymin related 1 [Source:HGNC Symbol;Acc:HGNC:17572]",{"v":0.279426983938548,"d":"0.28"},{"v":0.100826342527933,"d":"0.10"},{"v":2.77136884005423,"d":"2.77"},{"v":1.47059873113889,"d":"1.47"},1,1,"up","no"]
["ENSG00000144278","GALNT13","ENST00000392825","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0046872(metal ion binding);GO:0016740(transferase activity);GO:0030246(carbohydrate binding);GO:0016757(transferase activity, transferring glycosyl groups);GO:0005794(Golgi apparatus);GO:0000139(Golgi membrane);GO:0006486(protein glycosylation);GO:0016266(O-glycan processing);GO:0004653(polypeptide N-acetylgalactosaminyltransferase activity);GO:0006493(protein O-linked glycosylation)","00512(Mucin type O-glycan biosynthesis)","K00710","EC:2.4.1.41","polypeptide N-acetylgalactosaminyltransferase 13 [Source:HGNC Symbol;Acc:HGNC:23242]",0,{"v":0.0396027779141104,"d":"0.04"},"-inf","-inf",1,1,"down","no"]
["ENSG00000267270","PARD6G-AS1","ENST00000589574;ENST00000586421;ENST00000588226","NA","NA","NA","NA","PARD6G antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:44109]",{"v":0.0415190553497494,"d":"0.04"},{"v":0.0243148478971453,"d":"0.02"},{"v":1.70755973985031,"d":"1.71"},{"v":0.771936052821742,"d":"0.77"},1,1,"up","no"]
["ENSG00000270462","AC005034.2","ENST00000604464","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000227755","AP000344.1","ENST00000454268","NA","NA","NA","NA",null,0,{"v":0.0422761672955975,"d":"0.04"},"-inf","-inf",1,1,"down","no"]
["ENSG00000212932","RPL23AP4","ENST00000427757","NA","NA","NA","NA","ribosomal protein L23a pseudogene 4 [Source:HGNC Symbol;Acc:HGNC:10321]",{"v":0.259736,"d":"0.26"},{"v":0.149616,"d":"0.15"},{"v":1.73601753823121,"d":"1.74"},{"v":0.795781522777425,"d":"0.80"},1,1,"up","no"]
["ENSG00000222145","SNORA73","ENST00000410213","NA","NA","NA","NA","Small nucleolar RNA SNORA73 family [Source:RFAM;Acc:RF00045]",0,{"v":0.241396,"d":"0.24"},"-inf","-inf",1,1,"down","no"]
["ENSG00000124157","SEMG2","ENST00000372769","GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0005576(extracellular region);GO:0005615(extracellular space);GO:0005515(protein binding);GO:0070062(extracellular exosome);GO:0051291(protein heterooligomerization);GO:0019731(antibacterial humoral response);GO:0002020(protease binding);GO:0050817(coagulation);GO:1900005(positive regulation of serine-type endopeptidase activity);GO:1901318(negative regulation of flagellated sperm motility)","NA","NA","NA","semenogelin II [Source:HGNC Symbol;Acc:HGNC:10743]",{"v":0.018247,"d":"0.02"},{"v":0.022022,"d":"0.02"},{"v":0.828580510398692,"d":"0.83"},{"v":-0.271286208774731,"d":"-0.27"},1,1,"down","no"]
["ENSG00000163958","ZDHHC19","ENST00000438232;ENST00000465519;ENST00000460442;ENST00000296326;ENST00000397544","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016740(transferase activity);GO:0016746(transferase activity, transferring acyl groups);GO:0019706(protein-cysteine S-palmitoyltransferase activity);GO:0005783(endoplasmic reticulum);GO:0005783(endoplasmic reticulum)","NA","NA","NA","zinc finger DHHC-type containing 19 [Source:HGNC Symbol;Acc:HGNC:20713]",{"v":0.0604484913651316,"d":"0.06"},{"v":0.122589044407895,"d":"0.12"},{"v":0.493098642355014,"d":"0.49"},{"v":-1.02005181420486,"d":"-1.02"},1,1,"down","no"]
["ENSG00000264177","AL353997.2","ENST00000579352","NA","NA","NA","NA",null,{"v":0.010374,"d":"0.01"},{"v":0.009177,"d":"0.01"},{"v":1.1304347826087,"d":"1.13"},{"v":0.176877762084079,"d":"0.18"},1,1,"up","no"]
["MSTRG.1310","SYT2","ENST00000367267","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0046872(metal ion binding);GO:0007269(neurotransmitter secretion);GO:0008021(synaptic vesicle);GO:0030054(cell junction);GO:0045202(synapse);GO:0030154(cell differentiation);GO:0031410(cytoplasmic vesicle);GO:0005544(calcium-dependent phospholipid binding);GO:0005886(plasma membrane);GO:0005509(calcium ion binding);GO:0019905(syntaxin binding);GO:0030276(clathrin binding);GO:0006906(vesicle fusion);GO:0017158(regulation of calcium ion-dependent exocytosis);GO:0048791(calcium ion-regulated exocytosis of neurotransmitter);GO:0005515(protein binding);GO:0061024(membrane organization);GO:0030672(synaptic vesicle membrane);GO:0048488(synaptic vesicle endocytosis);GO:0030665(clathrin-coated vesicle membrane);GO:0043533(inositol 1,3,4,5 tetrakisphosphate binding);GO:1903861(positive regulation of dendrite extension);GO:0042584(chromaffin granule membrane)","NA","NA","NA","synaptotagmin 2 [Source:HGNC Symbol;Acc:HGNC:11510]",{"v":0.0668218116799588,"d":"0.07"},{"v":0.127344982505789,"d":"0.13"},{"v":0.524730620438235,"d":"0.52"},{"v":-0.930351114578012,"d":"-0.93"},1,1,"down","no"]
["ENSG00000256977","LIMS3","ENST00000480744;ENST00000631420;ENST00000437679;ENST00000482065;ENST00000479168","GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0016020(membrane);GO:0005886(plasma membrane);GO:0030054(cell junction);GO:0045216(cell-cell junction organization);GO:0005925(focal adhesion);GO:0005925(focal adhesion)","NA","NA","NA","LIM zinc finger domain containing 3 [Source:HGNC Symbol;Acc:HGNC:30047]",{"v":1.43523723800938,"d":"1.44"},0,"inf","inf",1,1,"up","no"]
["ENSG00000274797","AC008121.3","ENST00000618726","NA","NA","NA","NA",null,{"v":0.118316,"d":"0.12"},{"v":0.104313,"d":"0.10"},{"v":1.13424021933987,"d":"1.13"},{"v":0.181726219247218,"d":"0.18"},1,1,"up","no"]
["ENSG00000112530","PACRG","ENST00000544266;ENST00000534958;ENST00000337019;ENST00000611387","GO:0005634(nucleus);GO:0005829(cytosol);GO:0043005(neuron projection);GO:0031982(vesicle);GO:0030544(Hsp70 protein binding);GO:0031072(heat shock protein binding);GO:0031625(ubiquitin protein ligase binding);GO:0001664(G-protein coupled receptor binding);GO:0003779(actin binding);GO:0051087(chaperone binding);GO:0034620(cellular response to unfolded protein);GO:0051879(Hsp90 protein binding);GO:0060548(negative regulation of cell death);GO:0043014(alpha-tubulin binding);GO:0048487(beta-tubulin binding);GO:0007286(spermatid development);GO:0005739(mitochondrion);GO:0005929(cilium);GO:0044297(cell body);GO:0097225(sperm midpiece);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016021(integral component of membrane)","NA","NA","NA","parkin coregulated [Source:HGNC Symbol;Acc:HGNC:19152]",{"v":0.0589717400459418,"d":"0.06"},{"v":0.021542545941807,"d":"0.02"},{"v":2.73745453324052,"d":"2.74"},{"v":1.45283500299211,"d":"1.45"},1,1,"up","no"]
["ENSG00000227486","AL445472.1","ENST00000452532","NA","NA","NA","NA",null,{"v":0.145137,"d":"0.15"},0,"inf","inf",1,1,"up","no"]
["ENSG00000221852","KRTAP1-5","ENST00000361883","GO:0005515(protein binding);GO:0005882(intermediate filament);GO:0045095(keratin filament);GO:0003674(molecular_function);GO:0008150(biological_process);GO:0005575(cellular_component);GO:0005829(cytosol);GO:0031424(keratinization)","NA","NA","NA","keratin associated protein 1-5 [Source:HGNC Symbol;Acc:HGNC:16777]",0,{"v":0.038763,"d":"0.04"},"-inf","-inf",1,1,"down","no"]
["ENSG00000101230","ISM1","ENST00000262487","GO:0005576(extracellular region)","NA","NA","NA","isthmin 1 [Source:HGNC Symbol;Acc:HGNC:16213]",{"v":0.426071,"d":"0.43"},{"v":0.231613,"d":"0.23"},{"v":1.83958154335033,"d":"1.84"},{"v":0.879377628243331,"d":"0.88"},1,1,"up","no"]
["ENSG00000125657","TNFSF9","ENST00000245817","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0006955(immune response);GO:0005125(cytokine activity);GO:0005615(extracellular space);GO:0005164(tumor necrosis factor receptor binding);GO:0005886(plasma membrane);GO:0033209(tumor necrosis factor-mediated signaling pathway);GO:0007165(signal transduction);GO:0007267(cell-cell signaling);GO:0006915(apoptotic process);GO:0005102(receptor binding);GO:0008283(cell proliferation);GO:0032813(tumor necrosis factor receptor superfamily binding);GO:0042104(positive regulation of activated T cell proliferation);GO:0045585(positive regulation of cytotoxic T cell differentiation)","04060(Cytokine-cytokine receptor interaction)","K05472","NA","TNF superfamily member 9 [Source:HGNC Symbol;Acc:HGNC:11939]",{"v":0.330733,"d":"0.33"},{"v":0.027402,"d":"0.03"},{"v":12.0696664477045,"d":"12.07"},{"v":3.59331390180948,"d":"3.59"},1,1,"up","no"]
["ENSG00000247624","CPEB2-AS1","ENST00000500394","NA","NA","NA","NA","CPEB2 antisense RNA 1 (head to head) [Source:HGNC Symbol;Acc:HGNC:49082]",0,{"v":0.00593005503399158,"d":"0.01"},"-inf","-inf",1,1,"down","no"]
["ENSG00000250900","AC008443.6","ENST00000511517;ENST00000419707","NA","NA","NA","NA",null,{"v":0.0951976105121294,"d":"0.10"},0,"inf","inf",1,1,"up","no"]
["ENSG00000265190","ANXA8","ENST00000611843;ENST00000602877;ENST00000583448","GO:0046872(metal ion binding);GO:0005509(calcium ion binding);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0005544(calcium-dependent phospholipid binding);GO:0031902(late endosome membrane);GO:0051015(actin filament binding);GO:0016197(endosomal transport);GO:0005546(phosphatidylinositol-4,5-bisphosphate binding);GO:0005547(phosphatidylinositol-3,4,5-trisphosphate binding);GO:0043325(phosphatidylinositol-3,4-bisphosphate binding);GO:0007596(blood coagulation);GO:0007599(hemostasis);GO:0007032(endosome organization);GO:1900004(negative regulation of serine-type endopeptidase activity);GO:1900138(negative regulation of phospholipase A2 activity);GO:1900138(negative regulation of phospholipase A2 activity)","NA","NA","NA","annexin A8 [Source:HGNC Symbol;Acc:HGNC:546]",{"v":0.0132107265388496,"d":"0.01"},{"v":0.0149419816347124,"d":"0.01"},{"v":0.884134839796561,"d":"0.88"},{"v":-0.177661682430244,"d":"-0.18"},1,1,"down","no"]
["ENSG00000233058","LINC00884","ENST00000448892","NA","NA","NA","NA","long intergenic non-protein coding RNA 884 [Source:HGNC Symbol;Acc:HGNC:48570]",{"v":0.339748240930869,"d":"0.34"},{"v":0.140464284736482,"d":"0.14"},{"v":2.41875179564865,"d":"2.42"},{"v":1.27426273229475,"d":"1.27"},1,1,"up","no"]
["ENSG00000135447","PPP1R1A","ENST00000547431","GO:0007165(signal transduction);GO:0004864(protein phosphatase inhibitor activity);GO:0043086(negative regulation of catalytic activity);GO:0005515(protein binding);GO:0005975(carbohydrate metabolic process);GO:0005737(cytoplasm);GO:0035556(intracellular signal transduction);GO:0006469(negative regulation of protein kinase activity);GO:0005977(glycogen metabolic process);GO:0004865(protein serine/threonine phosphatase inhibitor activity);GO:0005615(extracellular space)","04261(Adrenergic signaling in cardiomyocytes);04720(Long-term potentiation)","NA","NA","protein phosphatase 1 regulatory inhibitor subunit 1A [Source:HGNC Symbol;Acc:HGNC:9286]",{"v":0.0215469623304872,"d":"0.02"},{"v":0.0114578493219488,"d":"0.01"},{"v":1.88054160297008,"d":"1.88"},{"v":0.911148223280479,"d":"0.91"},1,1,"up","no"]
["ENSG00000226530","AL158055.1","ENST00000418775","NA","NA","NA","NA",null,{"v":0.10675651843044,"d":"0.11"},{"v":0.158326608799049,"d":"0.16"},{"v":0.674280332536758,"d":"0.67"},{"v":-0.568579577253243,"d":"-0.57"},1,1,"down","no"]
["ENSG00000130182","ZSCAN10","ENST00000576985;ENST00000573931","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0043565(sequence-specific DNA binding);GO:0045892(negative regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0005654(nucleoplasm);GO:0035019(somatic stem cell population maintenance);GO:0035019(somatic stem cell population maintenance)","NA","NA","NA","zinc finger and SCAN domain containing 10 [Source:HGNC Symbol;Acc:HGNC:12997]",{"v":0.0688105290750226,"d":"0.07"},{"v":0.0262552832178367,"d":"0.03"},{"v":2.62082600686919,"d":"2.62"},{"v":1.39002157825267,"d":"1.39"},1,1,"up","no"]
["ENSG00000137434","C6orf52","ENST00000460742;ENST00000259983","NA","NA","NA","NA","chromosome 6 open reading frame 52 [Source:HGNC Symbol;Acc:HGNC:20881]",{"v":0.0651245418552036,"d":"0.07"},0,"inf","inf",1,1,"up","no"]
["ENSG00000214285","NPS","ENST00000398023","GO:0005576(extracellular region);GO:0007218(neuropeptide signaling pathway);GO:0008542(visual learning);GO:0010841(positive regulation of circadian sleep/wake cycle, wakefulness);GO:0032230(positive regulation of synaptic transmission, GABAergic);GO:0045760(positive regulation of action potential);GO:0051968(positive regulation of synaptic transmission, glutamatergic)","NA","NA","NA","neuropeptide S [Source:HGNC Symbol;Acc:HGNC:33940]",0,{"v":0.055967,"d":"0.06"},"-inf","-inf",1,1,"down","no"]
["ENSG00000227942","FRMD8P1","ENST00000440433","NA","NA","NA","NA","FERM domain containing 8 pseudogene 1 [Source:HGNC Symbol;Acc:HGNC:24690]",{"v":0.067457,"d":"0.07"},0,"inf","inf",1,1,"up","no"]
["ENSG00000259076","AL049869.2","ENST00000554454","NA","NA","NA","NA",null,0,{"v":0.0281629537037037,"d":"0.03"},"-inf","-inf",1,1,"down","no"]
["ENSG00000172497","ACOT12","ENST00000506440;ENST00000307624","GO:0005737(cytoplasm);GO:0016787(hydrolase activity);GO:0006629(lipid metabolic process);GO:0006631(fatty acid metabolic process);GO:0008289(lipid binding);GO:0052689(carboxylic ester hydrolase activity);GO:0005829(cytosol);GO:0047617(acyl-CoA hydrolase activity);GO:0006637(acyl-CoA metabolic process);GO:0003986(acetyl-CoA hydrolase activity);GO:0006090(pyruvate metabolic process);GO:0005524(ATP binding);GO:0006084(acetyl-CoA metabolic process);GO:0006084(acetyl-CoA metabolic process)","00620(Pyruvate metabolism);00620(Pyruvate metabolism)","K01067","EC:3.1.2.1","acyl-CoA thioesterase 12 [Source:HGNC Symbol;Acc:HGNC:24436]",{"v":0.0241720720130933,"d":"0.02"},{"v":0.014959624386252,"d":"0.01"},{"v":1.61582078459855,"d":"1.62"},{"v":0.69226719344315,"d":"0.69"},1,1,"up","no"]
["MSTRG.3262","AC023510.2","ENST00000622162","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000125409","TEKT3","ENST00000395931","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005856(cytoskeleton);GO:0042995(cell projection);GO:0005515(protein binding);GO:0005874(microtubule);GO:0060271(cilium assembly);GO:0005929(cilium);GO:0003674(molecular_function);GO:0070062(extracellular exosome);GO:0080154(regulation of fertilization);GO:0030317(flagellated sperm motility);GO:0002080(acrosomal membrane);GO:0060294(cilium movement involved in cell motility);GO:0036126(sperm flagellum)","NA","NA","NA","tektin 3 [Source:HGNC Symbol;Acc:HGNC:14293]",{"v":0.0483168493675738,"d":"0.05"},{"v":0.0155331314679954,"d":"0.02"},{"v":3.11056720707774,"d":"3.11"},{"v":1.6371776775344,"d":"1.64"},1,1,"up","no"]
["ENSG00000223573","TINCR","ENST00000448587","NA","NA","NA","NA","tissue differentiation-inducing non-protein coding RNA [Source:HGNC Symbol;Acc:HGNC:14607]",{"v":0.10468092866242,"d":"0.10"},0,"inf","inf",1,1,"up","no"]
["ENSG00000230076","RPL10P6","ENST00000457497","NA","NA","NA","NA","ribosomal protein L10 pseudogene 6 [Source:HGNC Symbol;Acc:HGNC:52343]",0,0,1,0,1,1,"no","no"]
["ENSG00000184925","LCN12","ENST00000466277;ENST00000470501;ENST00000484304;ENST00000496895","GO:0006810(transport);GO:0005215(transporter activity);GO:0006629(lipid metabolic process);GO:0005576(extracellular region);GO:0001972(retinoic acid binding);GO:0015909(long-chain fatty acid transport);GO:0015909(long-chain fatty acid transport)","NA","NA","NA","lipocalin 12 [Source:HGNC Symbol;Acc:HGNC:28733]",{"v":0.10332422135509,"d":"0.10"},{"v":0.0924213281305427,"d":"0.09"},{"v":1.11796944974808,"d":"1.12"},{"v":0.160880764836617,"d":"0.16"},1,1,"up","no"]
["MSTRG.6563","FOXN1","ENST00000226247","GO:0005634(nucleus);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0043565(sequence-specific DNA binding);GO:0007275(multicellular organism development);GO:0030154(cell differentiation);GO:0000981(RNA polymerase II transcription factor activity, sequence-specific DNA binding);GO:0006366(transcription from RNA polymerase II promoter);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0006952(defense response);GO:0009887(animal organ morphogenesis);GO:0008544(epidermis development);GO:0030858(positive regulation of epithelial cell differentiation);GO:0001228(transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding);GO:0001942(hair follicle development);GO:0002260(lymphocyte homeostasis);GO:0002360(T cell lineage commitment);GO:0008283(cell proliferation);GO:0010468(regulation of gene expression);GO:0030097(hemopoiesis);GO:0030216(keratinocyte differentiation);GO:0033081(regulation of T cell differentiation in thymus);GO:0035878(nail development);GO:0043029(T cell homeostasis);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0048514(blood vessel morphogenesis);GO:0048538(thymus development);GO:0050673(epithelial cell proliferation);GO:0051798(positive regulation of hair follicle development);GO:0097535(lymphoid lineage cell migration into thymus);GO:0097536(thymus epithelium morphogenesis);GO:1902232(regulation of positive thymic T cell selection)","NA","NA","NA","forkhead box N1 [Source:HGNC Symbol;Acc:HGNC:12765]",{"v":0.0117118757217487,"d":"0.01"},{"v":0.0468541160296948,"d":"0.05"},{"v":0.249964714184898,"d":"0.25"},{"v":-2.00020364105347,"d":"-2.00"},1,1,"down","no"]
["ENSG00000235321","AC007556.1","ENST00000432133","NA","NA","NA","NA",null,0,{"v":0.025801,"d":"0.03"},"-inf","-inf",1,1,"down","no"]
["ENSG00000004848","ARX","ENST00000379044","GO:0005634(nucleus);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0043565(sequence-specific DNA binding);GO:0007275(multicellular organism development);GO:0007399(nervous system development);GO:0030154(cell differentiation);GO:0000980(RNA polymerase II distal enhancer sequence-specific DNA binding);GO:0000981(RNA polymerase II transcription factor activity, sequence-specific DNA binding);GO:0001206(transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding);GO:0003682(chromatin binding);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0001764(neuron migration);GO:0007411(axon guidance);GO:0010628(positive regulation of gene expression);GO:0021759(globus pallidus development);GO:0021772(olfactory bulb development);GO:0021800(cerebral cortex tangential migration);GO:0021831(embryonic olfactory bulb interneuron precursor migration);GO:0021846(cell proliferation in forebrain);GO:0021853(cerebral cortex GABAergic interneuron migration);GO:0030900(forebrain development);GO:0042127(regulation of cell proliferation);GO:0044241(lipid digestion);GO:0046622(positive regulation of organ growth);GO:0072148(epithelial cell fate commitment)","NA","NA","NA","aristaless related homeobox [Source:HGNC Symbol;Acc:HGNC:18060]",{"v":0.0106217914110429,"d":"0.01"},{"v":0.0130056118824669,"d":"0.01"},{"v":0.81670831845769,"d":"0.82"},{"v":-0.292107172758587,"d":"-0.29"},1,1,"down","no"]
["ENSG00000183379","SYNDIG1L","ENST00000331628","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005794(Golgi apparatus);GO:0009607(response to biotic stimulus)","NA","NA","NA","synapse differentiation inducing 1 like [Source:HGNC Symbol;Acc:HGNC:32388]",0,{"v":0.0347593346094946,"d":"0.03"},"-inf","-inf",1,1,"down","no"]
["ENSG00000169314","C22orf15","ENST00000477921;ENST00000498542","NA","NA","NA","NA","chromosome 22 open reading frame 15 [Source:HGNC Symbol;Acc:HGNC:15558]",{"v":0.130106476989453,"d":"0.13"},{"v":0.0832572555129434,"d":"0.08"},{"v":1.56270436958166,"d":"1.56"},{"v":0.644044876943636,"d":"0.64"},1,1,"up","no"]
["MSTRG.8545","AC008073.1","ENST00000429717","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000131668","BARX1","ENST00000253968","GO:0005634(nucleus);GO:0006355(regulation of transcription, DNA-templated);GO:0006366(transcription from RNA polymerase II promoter);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0043565(sequence-specific DNA binding);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0000977(RNA polymerase II regulatory region sequence-specific DNA binding);GO:0001228(transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding);GO:0009888(tissue development);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0048513(animal organ development);GO:0007267(cell-cell signaling);GO:0009952(anterior/posterior pattern specification);GO:0030178(negative regulation of Wnt signaling pathway);GO:0030855(epithelial cell differentiation);GO:0048536(spleen development);GO:0048856(anatomical structure development);GO:0055123(digestive system development)","NA","NA","NA","BARX homeobox 1 [Source:HGNC Symbol;Acc:HGNC:955]",0,{"v":0.0784512965672482,"d":"0.08"},"-inf","-inf",1,1,"down","no"]
["ENSG00000184524","CEND1","ENST00000330106","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0030182(neuron differentiation);GO:0030154(cell differentiation);GO:0007628(adult walking behavior);GO:0021549(cerebellum development);GO:0021686(cerebellar granular layer maturation);GO:0021702(cerebellar Purkinje cell differentiation);GO:0021933(radial glia guided migration of cerebellar granule cell);GO:0021941(negative regulation of cerebellar granule cell precursor proliferation)","NA","NA","NA","cell cycle exit and neuronal differentiation 1 [Source:HGNC Symbol;Acc:HGNC:24153]",{"v":0.18703,"d":"0.19"},{"v":0.02361,"d":"0.02"},{"v":7.92164337145277,"d":"7.92"},{"v":2.98579975327261,"d":"2.99"},1,1,"up","no"]
["MSTRG.12734","HIST1H4D","ENST00000614247","GO:0005634(nucleus);GO:0003723(RNA binding);GO:0016020(membrane);GO:0003677(DNA binding);GO:0046982(protein heterodimerization activity);GO:0006334(nucleosome assembly);GO:0000786(nucleosome);GO:0005694(chromosome);GO:0005515(protein binding);GO:0006352(DNA-templated transcription, initiation);GO:0005576(extracellular region);GO:0005654(nucleoplasm);GO:0070062(extracellular exosome);GO:0044267(cellular protein metabolic process);GO:1902036(regulation of hematopoietic stem cell differentiation);GO:0043234(protein complex);GO:0000784(nuclear chromosome, telomeric region);GO:0034080(CENP-A containing nucleosome assembly);GO:0031012(extracellular matrix);GO:0045815(positive regulation of gene expression, epigenetic);GO:0019904(protein domain specific binding);GO:0042393(histone binding);GO:1904837(beta-catenin-TCF complex assembly);GO:0045652(regulation of megakaryocyte differentiation);GO:0006335(DNA replication-dependent nucleosome assembly);GO:0006336(DNA replication-independent nucleosome assembly);GO:0000228(nuclear chromosome);GO:0060964(regulation of gene silencing by miRNA);GO:0000183(chromatin silencing at rDNA);GO:0045814(negative regulation of gene expression, epigenetic);GO:0006303(double-strand break repair via nonhomologous end joining);GO:0051290(protein heterotetramerization);GO:0045653(negative regulation of megakaryocyte differentiation);GO:0016233(telomere capping);GO:0032200(telomere organization);GO:0000788(nuclear nucleosome)","05203(Viral carcinogenesis);05322(Systemic lupus erythematosus);05034(Alcoholism)","K11254","NA","histone cluster 1 H4 family member d [Source:HGNC Symbol;Acc:HGNC:4782]",{"v":0.814964,"d":"0.81"},0,"inf","inf",1,1,"up","no"]
["ENSG00000111700","SLCO1B3","ENST00000261196","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005215(transporter activity);GO:0006811(ion transport);GO:0005886(plasma membrane);GO:0015125(bile acid transmembrane transporter activity);GO:0015347(sodium-independent organic anion transmembrane transporter activity);GO:0043252(sodium-independent organic anion transport);GO:0016323(basolateral plasma membrane);GO:0005887(integral component of plasma membrane);GO:0008514(organic anion transmembrane transporter activity);GO:0015721(bile acid and bile salt transport);GO:0015711(organic anion transport)","04976(Bile secretion)","NA","NA","solute carrier organic anion transporter family member 1B3 [Source:HGNC Symbol;Acc:HGNC:10961]",{"v":0.00996806324110672,"d":"0.01"},{"v":0.0184840542066629,"d":"0.02"},{"v":0.539279052617881,"d":"0.54"},{"v":-0.890896098997783,"d":"-0.89"},1,1,"down","no"]
["ENSG00000102128","RAB40AL","ENST00000218249","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005525(GTP binding);GO:0000166(nucleotide binding);GO:0016567(protein ubiquitination);GO:0035556(intracellular signal transduction);GO:0003924(GTPase activity);GO:0005739(mitochondrion);GO:0005886(plasma membrane);GO:0005768(endosome);GO:0008021(synaptic vesicle);GO:0072659(protein localization to plasma membrane);GO:0030667(secretory granule membrane)","NA","NA","NA","RAB40A like [Source:HGNC Symbol;Acc:HGNC:25410]",{"v":0.07493,"d":"0.07"},0,"inf","inf",1,1,"up","no"]
["ENSG00000281571","AC241585.3","ENST00000628937;ENST00000638358","NA","NA","NA","NA",null,{"v":2.44451031709559,"d":"2.44"},0,"inf","inf",1,1,"up","no"]
["ENSG00000230799","AC007279.1","ENST00000448547","NA","NA","NA","NA",null,0,{"v":0.054509,"d":"0.05"},"-inf","-inf",1,1,"down","no"]
["ENSG00000233822","HIST1H2BN","ENST00000449538;ENST00000612898","GO:0005634(nucleus);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0003677(DNA binding);GO:0046982(protein heterodimerization activity);GO:0006334(nucleosome assembly);GO:0000786(nucleosome);GO:0005694(chromosome);GO:0016567(protein ubiquitination);GO:0070062(extracellular exosome);GO:0070062(extracellular exosome)","05203(Viral carcinogenesis);05322(Systemic lupus erythematosus);05034(Alcoholism);05034(Alcoholism)","K11252","NA","histone cluster 1 H2B family member n [Source:HGNC Symbol;Acc:HGNC:4749]",{"v":0.0129511915282089,"d":"0.01"},{"v":0.0116065723936462,"d":"0.01"},{"v":1.11584980379727,"d":"1.12"},{"v":0.158142849837784,"d":"0.16"},1,1,"up","no"]
["MSTRG.15502","AVPR2","ENST00000370049;ENST00000434679","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0004930(G-protein coupled receptor activity);GO:0007186(G-protein coupled receptor signaling pathway);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0004871(signal transducer activity);GO:0007165(signal transduction);GO:0005000(vasopressin receptor activity);GO:0032870(cellular response to hormone stimulus);GO:0010628(positive regulation of gene expression);GO:0061024(membrane organization);GO:0005887(integral component of plasma membrane);GO:0005783(endoplasmic reticulum);GO:0005794(Golgi apparatus);GO:0007588(excretion);GO:0031398(positive regulation of protein ubiquitination);GO:0003091(renal water homeostasis);GO:0030665(clathrin-coated vesicle membrane);GO:0007188(adenylate cyclase-modulating G-protein coupled receptor signaling pathway);GO:0042277(peptide binding);GO:1901652(response to peptide);GO:0005768(endosome);GO:0007599(hemostasis);GO:0007190(activation of adenylate cyclase activity);GO:0045907(positive regulation of vasoconstriction);GO:0001992(regulation of systemic arterial blood pressure by vasopressin);GO:0003084(positive regulation of systemic arterial blood pressure);GO:0007249(I-kappaB kinase/NF-kappaB signaling);GO:0008284(positive regulation of cell proliferation);GO:0021537(telencephalon development);GO:0032609(interferon-gamma production);GO:0034097(response to cytokine);GO:0035811(negative regulation of urine volume);GO:0035814(negative regulation of renal sodium excretion);GO:0045777(positive regulation of blood pressure);GO:0045777(positive regulation of blood pressure)","04072(Phospholipase D signaling pathway);04080(Neuroactive ligand-receptor interaction);04962(Vasopressin-regulated water reabsorption);04962(Vasopressin-regulated water reabsorption)","K04228","NA","arginine vasopressin receptor 2 [Source:HGNC Symbol;Acc:HGNC:897]",{"v":0.0915306140744061,"d":"0.09"},{"v":0.0518210667861945,"d":"0.05"},{"v":1.7662819341803,"d":"1.77"},{"v":0.820715644560386,"d":"0.82"},1,1,"up","no"]
["ENSG00000230730","AC074011.1","ENST00000431376","NA","NA","NA","NA",null,{"v":0.608374,"d":"0.61"},{"v":0.590933,"d":"0.59"},{"v":1.02951434426576,"d":"1.03"},{"v":0.0419639312396302,"d":"0.04"},1,1,"up","no"]
["ENSG00000277496","AL357033.4","ENST00000617703","NA","NA","NA","NA",null,0,{"v":0.684316,"d":"0.68"},"-inf","-inf",1,1,"down","no"]
["ENSG00000241081","AF111169.1","ENST00000469811","NA","NA","NA","NA",null,{"v":0.137439,"d":"0.14"},0,"inf","inf",1,1,"up","no"]
["ENSG00000275088","AC026469.1","ENST00000621095","NA","NA","NA","NA",null,{"v":0.031096,"d":"0.03"},0,"inf","inf",1,1,"up","no"]
["MSTRG.5999","AC010542.1","ENST00000568430","NA","NA","NA","NA",null,0,{"v":0.07595,"d":"0.08"},"-inf","-inf",1,1,"down","no"]
["ENSG00000092607","TBX15","ENST00000369429","GO:0005634(nucleus);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0005515(protein binding);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0000976(transcription regulatory region sequence-specific DNA binding);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:0001078(transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0001106(RNA polymerase II transcription corepressor activity);GO:0042803(protein homodimerization activity);GO:0046982(protein heterodimerization activity);GO:0048701(embryonic cranial skeleton morphogenesis);GO:0048704(embryonic skeletal system morphogenesis);GO:0070722(Tle3-Aes complex)","NA","NA","NA","T-box 15 [Source:HGNC Symbol;Acc:HGNC:11594]",{"v":0.0105276510772465,"d":"0.01"},{"v":0.0147304256437204,"d":"0.01"},{"v":0.714687500000005,"d":"0.71"},{"v":-0.484615539363042,"d":"-0.48"},1,1,"down","no"]
["ENSG00000261535","AC005086.1","ENST00000566572","NA","NA","NA","NA",null,0,{"v":0.227834,"d":"0.23"},"-inf","-inf",1,1,"down","no"]
["MSTRG.10137","AC000078.1","ENST00000420617","NA","NA","NA","NA",null,0,{"v":0.201137,"d":"0.20"},"-inf","-inf",1,1,"down","no"]
["MSTRG.9794","AL031663.3","ENST00000617473","NA","NA","NA","NA",null,{"v":0.114609,"d":"0.11"},{"v":0.050185,"d":"0.05"},{"v":2.28373019826641,"d":"2.28"},{"v":1.19139221960845,"d":"1.19"},1,1,"up","no"]
["ENSG00000279342","AP000866.6","ENST00000638898","NA","NA","NA","NA",null,{"v":0.242816,"d":"0.24"},0,"inf","inf",1,1,"up","no"]
["ENSG00000171403","KRT9","ENST00000246662","GO:0005634(nucleus);GO:0016020(membrane);GO:0005198(structural molecule activity);GO:0005882(intermediate filament);GO:0005615(extracellular space);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0031424(keratinization);GO:0005200(structural constituent of cytoskeleton);GO:0008544(epidermis development);GO:0070268(cornification);GO:0045109(intermediate filament organization);GO:0043588(skin development);GO:0007283(spermatogenesis)","NA","NA","NA","keratin 9 [Source:HGNC Symbol;Acc:HGNC:6447]",{"v":0.014646,"d":"0.01"},{"v":0.019923,"d":"0.02"},{"v":0.735130251468152,"d":"0.74"},{"v":-0.443928203443362,"d":"-0.44"},1,1,"down","no"]
["ENSG00000174844","DNAH12","ENST00000462713;ENST00000495027;ENST00000479363","GO:0005524(ATP binding);GO:0003777(microtubule motor activity);GO:0007018(microtubule-based movement);GO:0016887(ATPase activity);GO:0030286(dynein complex);GO:0005737(cytoplasm);GO:0000166(nucleotide binding);GO:0005856(cytoskeleton);GO:0042995(cell projection);GO:0005874(microtubule);GO:0003774(motor activity);GO:0005929(cilium);GO:0005929(cilium)","05016(Huntington's disease);05016(Huntington's disease)","K10408","NA","dynein axonemal heavy chain 12 [Source:HGNC Symbol;Acc:HGNC:2943]",{"v":0.00807537446327684,"d":"0.01"},{"v":0.0021464795480226,"d":"0.00"},{"v":3.76214833759591,"d":"3.76"},{"v":1.91155673394748,"d":"1.91"},1,1,"up","no"]
["ENSG00000162981","FAM84A","ENST00000295092","NA","NA","NA","NA","family with sequence similarity 84 member A [Source:HGNC Symbol;Acc:HGNC:20743]",0,{"v":0.0150552254293893,"d":"0.02"},"-inf","-inf",1,1,"down","no"]
["ENSG00000066468","FGFR2","ENST00000613048;ENST00000491475;ENST00000638709;ENST00000358487","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0043231(intracellular membrane-bounded organelle);GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0005654(nucleoplasm);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0008284(positive regulation of cell proliferation);GO:0005794(Golgi apparatus);GO:0004713(protein tyrosine kinase activity);GO:0042803(protein homodimerization activity);GO:0005886(plasma membrane);GO:0043547(positive regulation of GTPase activity);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0004714(transmembrane receptor protein tyrosine kinase activity);GO:0006915(apoptotic process);GO:0031410(cytoplasmic vesicle);GO:0036092(phosphatidylinositol-3-phosphate biosynthetic process);GO:0046854(phosphatidylinositol phosphorylation);GO:0008543(fibroblast growth factor receptor signaling pathway);GO:0005007(fibroblast growth factor-activated receptor activity);GO:0048701(embryonic cranial skeleton morphogenesis);GO:0005887(integral component of plasma membrane);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0008201(heparin binding);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0007409(axonogenesis);GO:0031012(extracellular matrix);GO:0060348(bone development);GO:0005938(cell cortex);GO:0000165(MAPK cascade);GO:0030282(bone mineralization);GO:0060349(bone morphogenesis);GO:0090263(positive regulation of canonical Wnt signaling pathway);GO:0070374(positive regulation of ERK1 and ERK2 cascade);GO:0009986(cell surface);GO:0030855(epithelial cell differentiation);GO:0046934(phosphatidylinositol-4,5-bisphosphate 3-kinase activity);GO:0014066(regulation of phosphatidylinositol 3-kinase signaling);GO:0038111(interleukin-7-mediated signaling pathway);GO:0048015(phosphatidylinositol-mediated signaling);GO:0031069(hair follicle morphogenesis);GO:0048562(embryonic organ morphogenesis);GO:0046777(protein autophosphorylation);GO:0005088(Ras guanyl-nucleotide exchange factor activity);GO:0016303(1-phosphatidylinositol-3-kinase activity);GO:0001525(angiogenesis);GO:0035265(organ growth);GO:0001701(in utero embryonic development);GO:0007267(cell-cell signaling);GO:0051781(positive regulation of cell division);GO:0022612(gland morphogenesis);GO:0009887(animal organ morphogenesis);GO:0045787(positive regulation of cell cycle);GO:0045165(cell fate commitment);GO:0032808(lacrimal gland development);GO:0043410(positive regulation of MAPK cascade);GO:0050679(positive regulation of epithelial cell proliferation);GO:0017134(fibroblast growth factor binding);GO:0002053(positive regulation of mesenchymal cell proliferation);GO:0003148(outflow tract septum morphogenesis);GO:0042472(inner ear morphogenesis);GO:0048286(lung alveolus development);GO:0048557(embryonic digestive tract morphogenesis);GO:0048608(reproductive structure development);GO:0060076(excitatory synapse);GO:0030901(midbrain development);GO:0030177(positive regulation of Wnt signaling pathway);GO:0001657(ureteric bud development);GO:0070372(regulation of ERK1 and ERK2 cascade);GO:0060484(lung-associated mesenchyme development);GO:0040014(regulation of multicellular organism growth);GO:0018108(peptidyl-tyrosine phosphorylation);GO:0042476(odontogenesis);GO:0008589(regulation of smoothened signaling pathway);GO:0030324(lung development);GO:0048565(digestive tract development);GO:0010518(positive regulation of phospholipase activity);GO:0048705(skeletal system morphogenesis);GO:0048762(mesenchymal cell differentiation);GO:0010453(regulation of cell fate commitment);GO:0033688(regulation of osteoblast proliferation);GO:0045667(regulation of osteoblast differentiation);GO:0003149(membranous septum morphogenesis);GO:0009791(post-embryonic development);GO:0009880(embryonic pattern specification);GO:0016331(morphogenesis of embryonic epithelium);GO:0021769(orbitofrontal cortex development);GO:0021847(ventricular zone neuroblast division);GO:0021860(pyramidal neuron development);GO:0030916(otic vesicle formation);GO:0035264(multicellular organism growth);GO:0035602(fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow);GO:0035603(fibroblast growth factor receptor signaling pathway involved in hemopoiesis);GO:0035604(fibroblast growth factor receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow);GO:0035607(fibroblast growth factor receptor signaling pathway involved in orbitofrontal cortex development);GO:0040036(regulation of fibroblast growth factor receptor signaling pathway);GO:0048568(embryonic organ development);GO:0048730(epidermis morphogenesis);GO:0048755(branching morphogenesis of a nerve);GO:0051150(regulation of smooth muscle cell differentiation);GO:0055010(ventricular cardiac muscle tissue morphogenesis);GO:0060045(positive regulation of cardiac muscle cell proliferation);GO:0060174(limb bud formation);GO:0060442(branching involved in prostate gland morphogenesis);GO:0060445(branching involved in salivary gland morphogenesis);GO:0060449(bud elongation involved in lung branching);GO:0060463(lung lobe morphogenesis);GO:0060501(positive regulation of epithelial cell proliferation involved in lung morphogenesis);GO:0060512(prostate gland morphogenesis);GO:0060523(prostate epithelial cord elongation);GO:0060527(prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis);GO:0060529(squamous basal epithelial stem cell differentiation involved in prostate gland acinus development);GO:0060595(fibroblast growth factor receptor signaling pathway involved in mammary gland specification);GO:0060601(lateral sprouting from an epithelium);GO:0060615(mammary gland bud formation);GO:0060664(epithelial cell proliferation involved in salivary gland morphogenesis);GO:0060667(branch elongation involved in salivary gland morphogenesis);GO:0060670(branching involved in labyrinthine layer morphogenesis);GO:0060687(regulation of branching involved in prostate gland morphogenesis);GO:0060688(regulation of morphogenesis of a branching structure);GO:0060915(mesenchymal cell differentiation involved in lung development);GO:0060916(mesenchymal cell proliferation involved in lung development);GO:0001837(epithelial to mesenchymal transition);GO:0003416(endochondral bone growth);GO:0032496(response to lipopolysaccharide);GO:0042060(wound healing);GO:0044344(cellular response to fibroblast growth factor stimulus);GO:0045471(response to ethanol);GO:0048333(mesodermal cell differentiation);GO:0048661(positive regulation of smooth muscle cell proliferation);GO:0050680(negative regulation of epithelial cell proliferation);GO:0071300(cellular response to retinoic acid);GO:0071560(cellular response to transforming growth factor beta stimulus);GO:0071560(cellular response to transforming growth factor beta stimulus)","04014(Ras signaling pathway);04015(Rap1 signaling pathway);04010(MAPK signaling pathway);04151(PI3K-Akt signaling pathway);04144(Endocytosis);04550(Signaling pathways regulating pluripotency of stem cells);04810(Regulation of actin cytoskeleton);05200(Pathways in cancer);05230(Central carbon metabolism in cancer);05226(Gastric cancer);05215(Prostate cancer);01521(EGFR tyrosine kinase inhibitor resistance);01521(EGFR tyrosine kinase inhibitor resistance)","K05093","EC:2.7.10.1","fibroblast growth factor receptor 2 [Source:HGNC Symbol;Acc:HGNC:3689]",{"v":0.0925071144967682,"d":"0.09"},{"v":0.0820123134151167,"d":"0.08"},{"v":1.12796616318492,"d":"1.13"},{"v":0.173723790309839,"d":"0.17"},1,1,"up","no"]
["ENSG00000105996","HOXA2","ENST00000612779","GO:0005634(nucleus);GO:0043231(intracellular membrane-bounded organelle);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0043565(sequence-specific DNA binding);GO:0007275(multicellular organism development)","NA","NA","NA","homeobox A2 [Source:HGNC Symbol;Acc:HGNC:5103]",0,0,1,0,1,1,"no","no"]
["ENSG00000264242","AC011840.4","ENST00000578471","NA","NA","NA","NA",null,0,{"v":0.25007,"d":"0.25"},"-inf","-inf",1,1,"down","no"]
["ENSG00000163531","NFASC","ENST00000339876","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0007155(cell adhesion);GO:0005886(plasma membrane);GO:0007411(axon guidance);GO:0050808(synapse organization);GO:0005925(focal adhesion);GO:0007422(peripheral nervous system development);GO:0019226(transmission of nerve impulse);GO:0042552(myelination);GO:0005515(protein binding);GO:0070062(extracellular exosome);GO:0043312(neutrophil degranulation);GO:0005622(intracellular);GO:0101003(ficolin-1-rich granule membrane);GO:0033268(node of Ranvier);GO:0043194(axon initial segment);GO:0034113(heterotypic cell-cell adhesion);GO:0019904(protein domain specific binding);GO:0086080(protein binding involved in heterotypic cell-cell adhesion);GO:0002175(protein localization to paranode region of axon);GO:0030913(paranodal junction assembly);GO:0045162(clustering of voltage-gated sodium channels);GO:0071205(protein localization to juxtaparanode region of axon);GO:0072661(protein targeting to plasma membrane);GO:0030424(axon);GO:0030425(dendrite);GO:0033010(paranodal junction);GO:0033270(paranode region of axon);GO:0043209(myelin sheath);GO:0097454(Schwann cell microvillus)","04514(Cell adhesion molecules (CAMs))","K06757","NA","neurofascin [Source:HGNC Symbol;Acc:HGNC:29866]",0,{"v":0.00978649889520944,"d":"0.01"},"-inf","-inf",1,1,"down","no"]
["ENSG00000257281","AC009729.1","ENST00000548873","NA","NA","NA","NA",null,{"v":0.045368,"d":"0.05"},{"v":0.060402,"d":"0.06"},{"v":0.751100956921956,"d":"0.75"},{"v":-0.412921258703528,"d":"-0.41"},1,1,"down","no"]
["ENSG00000253238","AC104212.3","ENST00000522044","NA","NA","NA","NA",null,0,{"v":0.021633,"d":"0.02"},"-inf","-inf",1,1,"down","no"]
["ENSG00000276850","AC245041.2","ENST00000610809","NA","NA","NA","NA",null,{"v":0.0208360105391163,"d":"0.02"},0,"inf","inf",1,1,"up","no"]
["ENSG00000230838","LINC01614","ENST00000415479","NA","NA","NA","NA","long intergenic non-protein coding RNA 1614 [Source:HGNC Symbol;Acc:HGNC:51847]",0,0,1,0,1,1,"no","no"]
["ENSG00000215246","AC116351.1","ENST00000399869","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000136695","IL36RN","ENST00000393200","GO:0005615(extracellular space);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0006955(immune response);GO:0006954(inflammatory response);GO:0005125(cytokine activity);GO:0005149(interleukin-1 receptor binding);GO:0005152(interleukin-1 receptor antagonist activity);GO:0001960(negative regulation of cytokine-mediated signaling pathway);GO:0002376(immune system process);GO:0045087(innate immune response);GO:0019732(antifungal humoral response);GO:0032700(negative regulation of interleukin-17 production);GO:1902714(negative regulation of interferon-gamma secretion);GO:0032715(negative regulation of interleukin-6 production)","NA","NA","NA","interleukin 36 receptor antagonist [Source:HGNC Symbol;Acc:HGNC:15561]",{"v":0.00540163685965444,"d":"0.01"},0,"inf","inf",1,1,"up","no"]
["ENSG00000105278","ZFR2","ENST00000262961;ENST00000439086;ENST00000586578","GO:0003676(nucleic acid binding);GO:0008270(zinc ion binding);GO:0008270(zinc ion binding)","NA","NA","NA","zinc finger RNA binding protein 2 [Source:HGNC Symbol;Acc:HGNC:29189]",{"v":0.02932333243607,"d":"0.03"},{"v":0.062582119448183,"d":"0.06"},{"v":0.468557675812646,"d":"0.47"},{"v":-1.09370145151196,"d":"-1.09"},1,1,"down","no"]
["ENSG00000170786","SDR16C5","ENST00000396721","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005886(plasma membrane);GO:0004745(retinol dehydrogenase activity);GO:0005634(nucleus);GO:0043616(keratinocyte proliferation);GO:0042572(retinol metabolic process);GO:0033613(activating transcription factor binding);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0017053(transcriptional repressor complex);GO:0042574(retinal metabolic process);GO:0008134(transcription factor binding);GO:0000785(chromatin);GO:0001191(transcriptional repressor activity, RNA polymerase II transcription factor binding);GO:0031065(positive regulation of histone deacetylation);GO:0035067(negative regulation of histone acetylation)","00830(Retinol metabolism)","K15734","EC:1.1.1.105","short chain dehydrogenase/reductase family 16C member 5 [Source:HGNC Symbol;Acc:HGNC:30311]",{"v":0.02678773589509,"d":"0.03"},{"v":0.0263904632509912,"d":"0.03"},{"v":1.01505364420171,"d":"1.02"},{"v":0.02155597389194,"d":"0.02"},1,1,"up","no"]
["ENSG00000197919","IFNA1","ENST00000276927","GO:0005576(extracellular region);GO:0005125(cytokine activity);GO:0005615(extracellular space);GO:0006952(defense response);GO:0045087(innate immune response);GO:0005126(cytokine receptor binding);GO:0051607(defense response to virus);GO:0019221(cytokine-mediated signaling pathway);GO:0060337(type I interferon signaling pathway);GO:0007596(blood coagulation);GO:0002250(adaptive immune response);GO:0005132(type I interferon receptor binding);GO:0002286(T cell activation involved in immune response);GO:0002323(natural killer cell activation involved in immune response);GO:0006959(humoral immune response);GO:0030183(B cell differentiation);GO:0033141(positive regulation of peptidyl-serine phosphorylation of STAT protein);GO:0042100(B cell proliferation);GO:0043330(response to exogenous dsRNA);GO:0060338(regulation of type I interferon-mediated signaling pathway)","04630(Jak-STAT signaling pathway);04151(PI3K-Akt signaling pathway);04060(Cytokine-cytokine receptor interaction);04217(Necroptosis);04620(Toll-like receptor signaling pathway);04621(NOD-like receptor signaling pathway);04622(RIG-I-like receptor signaling pathway);04623(Cytosolic DNA-sensing pathway);04650(Natural killer cell mediated cytotoxicity);05200(Pathways in cancer);05320(Autoimmune thyroid disease);05152(Tuberculosis);05162(Measles);05164(Influenza A);05161(Hepatitis B);05160(Hepatitis C);05168(Herpes simplex infection);05167(Kaposi's sarcoma-associated herpesvirus infection);05165(Human papillomavirus infection)","K05414","NA","interferon alpha 1 [Source:HGNC Symbol;Acc:HGNC:5417]",{"v":0.059562,"d":"0.06"},{"v":0.047756,"d":"0.05"},{"v":1.2472150096323,"d":"1.25"},{"v":0.318710195393188,"d":"0.32"},1,1,"up","no"]
["ENSG00000019144","PHLDB1","ENST00000525427;ENST00000620788;ENST00000532517;ENST00000530994;ENST00000392852","GO:0070507(regulation of microtubule cytoskeleton organization);GO:0010717(regulation of epithelial to mesenchymal transition);GO:0010470(regulation of gastrulation);GO:1904261(positive regulation of basement membrane assembly involved in embryonic body morphogenesis);GO:0045180(basal cortex);GO:0045180(basal cortex)","NA","NA","NA","pleckstrin homology like domain family B member 1 [Source:HGNC Symbol;Acc:HGNC:23697]",{"v":0.0220292488260749,"d":"0.02"},{"v":0.0290963440290949,"d":"0.03"},{"v":0.757113979819827,"d":"0.76"},{"v":-0.401417587618857,"d":"-0.40"},1,1,"down","no"]
["ENSG00000234473","ZNF101P2","ENST00000439152","NA","NA","NA","NA","zinc finger protein 101 pseudogene 2 [Source:HGNC Symbol;Acc:HGNC:44942]",0,{"v":0.037123,"d":"0.04"},"-inf","-inf",1,1,"down","no"]
["ENSG00000274415","AC241644.3","ENST00000622634","NA","NA","NA","NA",null,0,{"v":1.1372754491018E-4,"d":"0.00"},"-inf","-inf",1,1,"down","no"]
["MSTRG.6853","MIR6781","ENST00000621616","NA","NA","NA","NA","microRNA 6781 [Source:HGNC Symbol;Acc:HGNC:50185]",{"v":0.009816,"d":"0.01"},{"v":0.011485,"d":"0.01"},{"v":0.854680017414018,"d":"0.85"},{"v":-0.226543702602381,"d":"-0.23"},1,1,"down","no"]
["ENSG00000221867","MAGEA3","ENST00000598245","GO:0005515(protein binding);GO:0005783(endoplasmic reticulum);GO:1902236(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway);GO:0089720(caspase binding);GO:0010955(negative regulation of protein processing);GO:0043154(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)","NA","NA","NA","MAGE family member A3 [Source:HGNC Symbol;Acc:HGNC:6801]",{"v":0.0402756935123042,"d":"0.04"},{"v":0.0159328948545861,"d":"0.02"},{"v":2.52783275606136,"d":"2.53"},{"v":1.33790101652829,"d":"1.34"},1,1,"up","no"]
["ENSG00000236992","RPL12P12","ENST00000424633","NA","NA","NA","NA","ribosomal protein L12 pseudogene 12 [Source:HGNC Symbol;Acc:HGNC:15951]",{"v":0.038988,"d":"0.04"},{"v":0.076394,"d":"0.08"},{"v":0.510354216299709,"d":"0.51"},{"v":-0.970429183652961,"d":"-0.97"},1,1,"down","no"]
["ENSG00000231982","AC112907.2","ENST00000448639","NA","NA","NA","NA",null,0,{"v":0.104824,"d":"0.10"},"-inf","-inf",1,1,"down","no"]
["MSTRG.13845","AC073517.1","ENST00000468165","NA","NA","NA","NA",null,{"v":0.131751,"d":"0.13"},{"v":0.521132,"d":"0.52"},{"v":0.252816944651259,"d":"0.25"},{"v":-1.98383493380472,"d":"-1.98"},1,1,"down","no"]
["ENSG00000224038","BX005214.1","ENST00000427327","NA","NA","NA","NA",null,0,{"v":0.293106,"d":"0.29"},"-inf","-inf",1,1,"down","no"]
["ENSG00000204787","REG1CP","ENST00000444841","NA","NA","NA","NA","regenerating family member 1 gamma, pseudogene [Source:HGNC Symbol;Acc:HGNC:9953]",{"v":0.0247672273781903,"d":"0.02"},0,"inf","inf",1,1,"up","no"]
["ENSG00000050165","DKK3","ENST00000532873;ENST00000531309;ENST00000526218;ENST00000396505","GO:0090090(negative regulation of canonical Wnt signaling pathway);GO:0005576(extracellular region);GO:0007275(multicellular organism development);GO:0016055(Wnt signaling pathway);GO:0030178(negative regulation of Wnt signaling pathway);GO:0005615(extracellular space);GO:0045892(negative regulation of transcription, DNA-templated);GO:0009653(anatomical structure morphogenesis);GO:0030325(adrenal gland development);GO:0032348(negative regulation of aldosterone biosynthetic process);GO:2000065(negative regulation of cortisol biosynthetic process);GO:0017015(regulation of transforming growth factor beta receptor signaling pathway);GO:1902613(negative regulation of anti-Mullerian hormone signaling pathway);GO:1902613(negative regulation of anti-Mullerian hormone signaling pathway)","NA","NA","NA","dickkopf WNT signaling pathway inhibitor 3 [Source:HGNC Symbol;Acc:HGNC:2893]",{"v":0.199793447321605,"d":"0.20"},{"v":0.0701924712393754,"d":"0.07"},{"v":2.84636576820689,"d":"2.85"},{"v":1.50912106526271,"d":"1.51"},1,1,"up","no"]
["ENSG00000173769","TOPAZ1","ENST00000309765","GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0005829(cytosol);GO:0006915(apoptotic process);GO:0007286(spermatid development);GO:0048137(spermatocyte division);GO:0098781(ncRNA transcription);GO:1901995(positive regulation of meiotic cell cycle phase transition)","NA","NA","NA","testis and ovary specific PAZ domain containing 1 [Source:HGNC Symbol;Acc:HGNC:24746]",{"v":0.006746,"d":"0.01"},{"v":0.015453,"d":"0.02"},{"v":0.436549537306672,"d":"0.44"},{"v":-1.19578272242632,"d":"-1.20"},1,1,"down","no"]
["MSTRG.10300","IGLC3","MSTRG.10300.1","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["MSTRG.12191","AC008840.1","ENST00000513235;ENST00000512486","NA","NA","NA","NA",null,0,{"v":0.041266501650165,"d":"0.04"},"-inf","-inf",1,1,"down","no"]
["MSTRG.11571","AC021106.2","ENST00000505310","NA","NA","NA","NA",null,0,{"v":0.05719,"d":"0.06"},"-inf","-inf",1,1,"down","no"]
["ENSG00000163283","ALPP","ENST00000392027","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0046872(metal ion binding);GO:0016787(hydrolase activity);GO:0003824(catalytic activity);GO:0008152(metabolic process);GO:0005886(plasma membrane);GO:0016791(phosphatase activity);GO:0016311(dephosphorylation);GO:0008270(zinc ion binding);GO:0005515(protein binding);GO:0000287(magnesium ion binding);GO:0004035(alkaline phosphatase activity);GO:0031225(anchored component of membrane);GO:0009986(cell surface)","00730(Thiamine metabolism);00790(Folate biosynthesis)","K01077","EC:3.1.3.1","alkaline phosphatase, placental [Source:HGNC Symbol;Acc:HGNC:439]",{"v":0.0392921791435109,"d":"0.04"},{"v":0.053612030075188,"d":"0.05"},{"v":0.732898550724636,"d":"0.73"},{"v":-0.448314583425612,"d":"-0.45"},1,1,"down","no"]
["ENSG00000078725","BRINP1","ENST00000265922","GO:0005737(cytoplasm);GO:0005515(protein binding);GO:0007049(cell cycle);GO:0005783(endoplasmic reticulum);GO:0045666(positive regulation of neuron differentiation);GO:0045930(negative regulation of mitotic cell cycle);GO:0007050(cell cycle arrest);GO:0045786(negative regulation of cell cycle);GO:0008219(cell death);GO:0030425(dendrite);GO:0043025(neuronal cell body);GO:0001662(behavioral fear response);GO:0007614(short-term memory);GO:0035176(social behavior);GO:0035640(exploration behavior);GO:0042711(maternal behavior);GO:0050768(negative regulation of neurogenesis);GO:0071300(cellular response to retinoic acid);GO:0071625(vocalization behavior)","NA","NA","NA","BMP/retinoic acid inducible neural specific 1 [Source:HGNC Symbol;Acc:HGNC:2687]",{"v":0.0236939800256082,"d":"0.02"},{"v":0.011682995134443,"d":"0.01"},{"v":2.02807411566536,"d":"2.03"},{"v":1.02011037637924,"d":"1.02"},1,1,"up","no"]
["ENSG00000241293","PPATP1","ENST00000496669","NA","NA","NA","NA","phosphoribosyl pyrophosphate amidotransferase pseudogene 1 [Source:HGNC Symbol;Acc:HGNC:9239]",0,{"v":0.057214,"d":"0.06"},"-inf","-inf",1,1,"down","no"]
["ENSG00000253883","IGHV3-19","ENST00000521488","NA","NA","NA","NA","immunoglobulin heavy variable 3-19 (pseudogene) [Source:HGNC Symbol;Acc:HGNC:5584]",{"v":0.170162,"d":"0.17"},{"v":0.156783,"d":"0.16"},{"v":1.08533450692996,"d":"1.09"},{"v":0.118139758902462,"d":"0.12"},1,1,"up","no"]
["MSTRG.7930","AC008894.2","ENST00000597983","NA","NA","NA","NA",null,{"v":0.130322041762159,"d":"0.13"},{"v":0.0534792419149478,"d":"0.05"},{"v":2.43687152427142,"d":"2.44"},{"v":1.28503019189736,"d":"1.29"},1,1,"up","no"]
["ENSG00000204683","C10orf113","ENST00000529198","NA","NA","NA","NA","chromosome 10 open reading frame 113 [Source:HGNC Symbol;Acc:HGNC:31447]",0,{"v":0.048721,"d":"0.05"},"-inf","-inf",1,1,"down","no"]
["ENSG00000262543","SMIM28","ENST00000573100","GO:0016020(membrane);GO:0016021(integral component of membrane)","NA","NA","NA","small integral membrane protein 28 [Source:HGNC Symbol;Acc:HGNC:53434]",0,{"v":0.04091,"d":"0.04"},"-inf","-inf",1,1,"down","no"]
["ENSG00000250431","AC105914.2","ENST00000507525","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000270127","AC027020.2","ENST00000602585","NA","NA","NA","NA",null,0,{"v":0.711763,"d":"0.71"},"-inf","-inf",1,1,"down","no"]
["MSTRG.492","SZT2-AS1","ENST00000396885","NA","NA","NA","NA","SZT2 antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:41225]",{"v":0.077399,"d":"0.08"},{"v":0.103759,"d":"0.10"},{"v":0.745949748937441,"d":"0.75"},{"v":-0.422849648589938,"d":"-0.42"},1,1,"down","no"]
["MSTRG.5219","AC016355.1","ENST00000604760","NA","NA","NA","NA",null,{"v":0.03353,"d":"0.03"},{"v":0.029761,"d":"0.03"},{"v":1.1266422499244,"d":"1.13"},{"v":0.172029479844267,"d":"0.17"},1,1,"up","no"]
["ENSG00000136883","KIF12","ENST00000639832","GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0003777(microtubule motor activity);GO:0008017(microtubule binding);GO:0005874(microtubule);GO:0003774(motor activity);GO:0007018(microtubule-based movement);GO:0005815(microtubule organizing center);GO:0005737(cytoplasm);GO:0005856(cytoskeleton);GO:0003674(molecular_function);GO:0008150(biological_process);GO:0070062(extracellular exosome);GO:0016887(ATPase activity);GO:0005871(kinesin complex)","NA","NA","NA","kinesin family member 12 [Source:HGNC Symbol;Acc:HGNC:21495]",{"v":0.0454106843501326,"d":"0.05"},{"v":0.0144718076923077,"d":"0.01"},{"v":3.13787229043059,"d":"3.14"},{"v":1.64978663665535,"d":"1.65"},1,1,"up","no"]
["MSTRG.5513","AL031710.2","ENST00000621884","NA","NA","NA","NA",null,0,{"v":0.063191,"d":"0.06"},"-inf","-inf",1,1,"down","no"]
["ENSG00000069122","ADGRF5","ENST00000283296","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0004930(G-protein coupled receptor activity);GO:0007186(G-protein coupled receptor signaling pathway);GO:0005886(plasma membrane);GO:0004871(signal transducer activity);GO:0007165(signal transduction);GO:0004888(transmembrane signaling receptor activity);GO:0007166(cell surface receptor signaling pathway);GO:0031410(cytoplasmic vesicle);GO:0009986(cell surface);GO:0006112(energy reserve metabolic process);GO:0019216(regulation of lipid metabolic process);GO:0042593(glucose homeostasis);GO:0043031(negative regulation of macrophage activation);GO:0043129(surfactant homeostasis);GO:0045444(fat cell differentiation);GO:0071073(positive regulation of phospholipid biosynthetic process);GO:0045177(apical part of cell)","NA","NA","NA","adhesion G protein-coupled receptor F5 [Source:HGNC Symbol;Acc:HGNC:19030]",{"v":0.0222352631578947,"d":"0.02"},{"v":0.0114950631578947,"d":"0.01"},{"v":1.93433153454435,"d":"1.93"},{"v":0.951835086568276,"d":"0.95"},1,1,"up","no"]
["ENSG00000217026","RPL10P1","ENST00000447844","NA","NA","NA","NA","ribosomal protein L10 pseudogene 1 [Source:HGNC Symbol;Acc:HGNC:10300]",0,{"v":0.034478,"d":"0.03"},"-inf","-inf",1,1,"down","no"]
["ENSG00000144407","PTH2R","ENST00000272847;ENST00000617735","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0004930(G-protein coupled receptor activity);GO:0007186(G-protein coupled receptor signaling pathway);GO:0004888(transmembrane signaling receptor activity);GO:0007166(cell surface receptor signaling pathway);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0004871(signal transducer activity);GO:0007165(signal transduction);GO:0005887(integral component of plasma membrane);GO:0004991(parathyroid hormone receptor activity);GO:0004991(parathyroid hormone receptor activity)","04080(Neuroactive ligand-receptor interaction);04080(Neuroactive ligand-receptor interaction)","K04586","NA","parathyroid hormone 2 receptor [Source:HGNC Symbol;Acc:HGNC:9609]",{"v":0.0197486624145786,"d":"0.02"},{"v":0.0541456708428246,"d":"0.05"},{"v":0.364732066426982,"d":"0.36"},{"v":-1.4550910511182,"d":"-1.46"},1,1,"down","no"]
["ENSG00000204176","SYT15","ENST00000374323;ENST00000374321;ENST00000449358;ENST00000374328","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005886(plasma membrane);GO:0098793(presynapse);GO:0005509(calcium ion binding);GO:0005544(calcium-dependent phospholipid binding);GO:0019905(syntaxin binding);GO:0030276(clathrin binding);GO:0006906(vesicle fusion);GO:0017158(regulation of calcium ion-dependent exocytosis);GO:0048791(calcium ion-regulated exocytosis of neurotransmitter);GO:0048791(calcium ion-regulated exocytosis of neurotransmitter)","NA","NA","NA","synaptotagmin 15 [Source:HGNC Symbol;Acc:HGNC:17167]",{"v":0.090854306789606,"d":"0.09"},{"v":0.0506869460743224,"d":"0.05"},{"v":1.7924596730761,"d":"1.79"},{"v":0.841940661405518,"d":"0.84"},1,1,"up","no"]
["ENSG00000179170","AF186996.1","ENST00000466578","NA","NA","NA","NA",null,0,{"v":0.04495,"d":"0.04"},"-inf","-inf",1,1,"down","no"]
["ENSG00000158571","PFKFB1","ENST00000545676;ENST00000375006","GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0016787(hydrolase activity);GO:0003824(catalytic activity);GO:0006096(glycolytic process);GO:0008152(metabolic process);GO:0016311(dephosphorylation);GO:0005515(protein binding);GO:0042802(identical protein binding);GO:0006003(fructose 2,6-bisphosphate metabolic process);GO:0006094(gluconeogenesis);GO:0006000(fructose metabolic process);GO:0003873(6-phosphofructo-2-kinase activity);GO:0005829(cytosol);GO:0004331(fructose-2,6-bisphosphate 2-phosphatase activity);GO:0045821(positive regulation of glycolytic process);GO:0019900(kinase binding);GO:0070095(fructose-6-phosphate binding);GO:0031100(animal organ regeneration);GO:0032868(response to insulin);GO:0033133(positive regulation of glucokinase activity);GO:0033762(response to glucagon);GO:0042594(response to starvation);GO:0045820(negative regulation of glycolytic process);GO:0046835(carbohydrate phosphorylation);GO:0051384(response to glucocorticoid);GO:0051591(response to cAMP);GO:0043540(6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex);GO:0043540(6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex)","00051(Fructose and mannose metabolism);04152(AMPK signaling pathway);04922(Glucagon signaling pathway);04922(Glucagon signaling pathway)","K19028","EC:2.7.1.105;EC:3.1.3.46","6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 [Source:HGNC Symbol;Acc:HGNC:8872]",{"v":0.0947314679300292,"d":"0.09"},{"v":0.0100424227405248,"d":"0.01"},{"v":9.43312887514221,"d":"9.43"},{"v":3.23773637789315,"d":"3.24"},1,1,"up","no"]
["ENSG00000198417","MT1F","ENST00000568475;ENST00000564295;ENST00000334350","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0008270(zinc ion binding);GO:0005515(protein binding);GO:0048471(perinuclear region of cytoplasm);GO:0045926(negative regulation of growth);GO:0071294(cellular response to zinc ion);GO:0071276(cellular response to cadmium ion);GO:0071276(cellular response to cadmium ion)","04978(Mineral absorption);04978(Mineral absorption)","K14739","NA","metallothionein 1F [Source:HGNC Symbol;Acc:HGNC:7398]",{"v":0.262678988883007,"d":"0.26"},{"v":0.190884111699312,"d":"0.19"},{"v":1.37611761683334,"d":"1.38"},{"v":0.460603782518559,"d":"0.46"},1,1,"up","no"]
["ENSG00000267366","AP005131.2","ENST00000589045","NA","NA","NA","NA",null,{"v":0.098512,"d":"0.10"},{"v":0.412573,"d":"0.41"},{"v":0.238774713808223,"d":"0.24"},{"v":-2.06627803129569,"d":"-2.07"},1,1,"down","no"]
["ENSG00000073670","ADAM11","ENST00000200557;ENST00000355638","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0006508(proteolysis);GO:0004222(metalloendopeptidase activity);GO:0008237(metallopeptidase activity);GO:0005886(plasma membrane);GO:0031012(extracellular matrix);GO:0005178(integrin binding);GO:0007229(integrin-mediated signaling pathway);GO:0007229(integrin-mediated signaling pathway)","NA","NA","NA","ADAM metallopeptidase domain 11 [Source:HGNC Symbol;Acc:HGNC:189]",{"v":0.0251587073375262,"d":"0.03"},{"v":0.0244974935010482,"d":"0.02"},{"v":1.02699108120795,"d":"1.03"},{"v":0.0384236527827549,"d":"0.04"},1,1,"up","no"]
["MSTRG.3820","AC048338.2","ENST00000623601","NA","NA","NA","NA",null,0,{"v":0.034993,"d":"0.03"},"-inf","-inf",1,1,"down","no"]
["ENSG00000135374","ELF5","ENST00000312319","GO:0005634(nucleus);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0000981(RNA polymerase II transcription factor activity, sequence-specific DNA binding);GO:0043565(sequence-specific DNA binding);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0030154(cell differentiation);GO:0006366(transcription from RNA polymerase II promoter);GO:0008283(cell proliferation);GO:0000977(RNA polymerase II regulatory region sequence-specific DNA binding);GO:0001228(transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding);GO:0001712(ectodermal cell fate commitment);GO:0007398(ectoderm development);GO:0035019(somatic stem cell population maintenance);GO:0045596(negative regulation of cell differentiation);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0060644(mammary gland epithelial cell differentiation);GO:0005737(cytoplasm)","04917(Prolactin signaling pathway)","K17101","NA","E74 like ETS transcription factor 5 [Source:HGNC Symbol;Acc:HGNC:3320]",0,{"v":0.0133092679127726,"d":"0.01"},"-inf","-inf",1,1,"down","no"]
["ENSG00000155269","GPR78","ENST00000382487;ENST00000514302","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0004930(G-protein coupled receptor activity);GO:0007186(G-protein coupled receptor signaling pathway);GO:0005886(plasma membrane);GO:0004871(signal transducer activity);GO:0007165(signal transduction);GO:0005515(protein binding);GO:0007189(adenylate cyclase-activating G-protein coupled receptor signaling pathway);GO:0007189(adenylate cyclase-activating G-protein coupled receptor signaling pathway)","NA","NA","NA","G protein-coupled receptor 78 [Source:HGNC Symbol;Acc:HGNC:4528]",{"v":0.0128430480746233,"d":"0.01"},{"v":0.0262437962209998,"d":"0.03"},{"v":0.489374630349649,"d":"0.49"},{"v":-1.03098878222658,"d":"-1.03"},1,1,"down","no"]
["ENSG00000204450","TRIM64","ENST00000533122","GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0005622(intracellular)","NA","NA","NA","tripartite motif containing 64 [Source:HGNC Symbol;Acc:HGNC:14663]",{"v":0.005362,"d":"0.01"},{"v":0.007347,"d":"0.01"},{"v":0.729821695930312,"d":"0.73"},{"v":-0.454384055302573,"d":"-0.45"},1,1,"down","no"]
["ENSG00000133101","CCNA1","ENST00000630422;ENST00000255465","GO:0005634(nucleus);GO:0051301(cell division);GO:0005515(protein binding);GO:0007049(cell cycle);GO:0005654(nucleoplasm);GO:0016579(protein deubiquitination);GO:0007283(spermatogenesis);GO:0005829(cytosol);GO:0000083(regulation of transcription involved in G1/S transition of mitotic cell cycle);GO:0015630(microtubule cytoskeleton);GO:0007141(male meiosis I);GO:0097123(cyclin A1-CDK2 complex);GO:0097123(cyclin A1-CDK2 complex)","04152(AMPK signaling pathway);04110(Cell cycle);04218(Cellular senescence);04914(Progesterone-mediated oocyte maturation);05200(Pathways in cancer);05202(Transcriptional misregulation in cancers);05203(Viral carcinogenesis);05221(Acute myeloid leukemia);05161(Hepatitis B);05169(Epstein-Barr virus infection);05165(Human papillomavirus infection);05165(Human papillomavirus infection)","K06627","NA","cyclin A1 [Source:HGNC Symbol;Acc:HGNC:1577]",{"v":0.0277245504166667,"d":"0.03"},{"v":0.126525596666667,"d":"0.13"},{"v":0.21912206815912,"d":"0.22"},{"v":-2.19019330695147,"d":"-2.19"},1,1,"down","no"]
["ENSG00000170381","SEMA3E","ENST00000307792","GO:0005515(protein binding);GO:0005576(extracellular region);GO:0007275(multicellular organism development);GO:0007399(nervous system development);GO:0030154(cell differentiation);GO:0005615(extracellular space);GO:0002040(sprouting angiogenesis);GO:0008360(regulation of cell shape);GO:0050808(synapse organization);GO:0001525(angiogenesis);GO:0016525(negative regulation of angiogenesis);GO:0071526(semaphorin-plexin signaling pathway);GO:0030215(semaphorin receptor binding);GO:0038191(neuropilin binding);GO:0001569(branching involved in blood vessel morphogenesis);GO:0001953(negative regulation of cell-matrix adhesion);GO:0050919(negative chemotaxis);GO:2000249(regulation of actin cytoskeleton reorganization)","04360(Axon guidance)","K06840","NA","semaphorin 3E [Source:HGNC Symbol;Acc:HGNC:10727]",{"v":0.0287849946650859,"d":"0.03"},{"v":0.0163454700652045,"d":"0.02"},{"v":1.761038046031,"d":"1.76"},{"v":0.816426077952383,"d":"0.82"},1,1,"up","no"]
["ENSG00000251686","OR10J8P","ENST00000504659","NA","NA","NA","NA","olfactory receptor family 10 subfamily J member 8 pseudogene [Source:HGNC Symbol;Acc:HGNC:19638]",0,{"v":0.04862,"d":"0.05"},"-inf","-inf",1,1,"down","no"]
["MSTRG.13955","FLNC","ENST00000325888","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005829(cytosol);GO:0051015(actin filament binding);GO:0003779(actin binding);GO:0005886(plasma membrane);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0005925(focal adhesion);GO:0042383(sarcolemma);GO:0030018(Z disc);GO:0008092(cytoskeletal protein binding);GO:0030506(ankyrin binding);GO:0034329(cell junction assembly);GO:0043034(costamere);GO:0048747(muscle fiber development);GO:0016528(sarcoplasm)","04010(MAPK signaling pathway);04510(Focal adhesion);05205(Proteoglycans in cancer);05132(Salmonella infection)","K04437","NA","filamin C [Source:HGNC Symbol;Acc:HGNC:3756]",{"v":0.0824692306034483,"d":"0.08"},{"v":0.0353213254310345,"d":"0.04"},{"v":2.33482831114226,"d":"2.33"},{"v":1.22331646694976,"d":"1.22"},1,1,"up","no"]
["ENSG00000166960","CCDC178","ENST00000383096","NA","NA","NA","NA","coiled-coil domain containing 178 [Source:HGNC Symbol;Acc:HGNC:29588]",{"v":0.0276167586592179,"d":"0.03"},{"v":0.020233850726257,"d":"0.02"},{"v":1.36487903527826,"d":"1.36"},{"v":0.448773095513401,"d":"0.45"},1,1,"up","no"]
["ENSG00000244280","ECEL1P2","ENST00000461596","NA","NA","NA","NA","endothelin converting enzyme like 1 pseudogene 2 [Source:HGNC Symbol;Acc:HGNC:14019]",0,{"v":0.0133556352459016,"d":"0.01"},"-inf","-inf",1,1,"down","no"]
["MSTRG.3272","REP15","ENST00000310791","GO:0016020(membrane);GO:0048471(perinuclear region of cytoplasm);GO:0005515(protein binding);GO:0005768(endosome);GO:0010008(endosome membrane);GO:0031901(early endosome membrane);GO:0055037(recycling endosome);GO:0033572(transferrin transport);GO:0001881(receptor recycling)","NA","NA","NA","RAB15 effector protein [Source:HGNC Symbol;Acc:HGNC:33748]",0,0,1,0,1,1,"no","no"]
["ENSG00000145002","FAM86B2","ENST00000262365;ENST00000309608","GO:0008168(methyltransferase activity);GO:0016740(transferase activity);GO:0032259(methylation);GO:0005515(protein binding);GO:0008150(biological_process);GO:0043234(protein complex);GO:0043234(protein complex)","NA","NA","NA","family with sequence similarity 86 member B2 [Source:HGNC Symbol;Acc:HGNC:32222]",{"v":0.0393859736456808,"d":"0.04"},{"v":0.0822445592972182,"d":"0.08"},{"v":0.478888500129795,"d":"0.48"},{"v":-1.06223830329949,"d":"-1.06"},1,1,"down","no"]
["ENSG00000254636","ARMS2","ENST00000528446","GO:0005737(cytoplasm);GO:0005739(mitochondrion);GO:0001895(retina homeostasis);GO:0001917(photoreceptor inner segment)","NA","NA","NA","age-related maculopathy susceptibility 2 [Source:HGNC Symbol;Acc:HGNC:32685]",{"v":0.056966,"d":"0.06"},{"v":0.08422,"d":"0.08"},{"v":0.676395155545001,"d":"0.68"},{"v":-0.564061767925142,"d":"-0.56"},1,1,"down","no"]
["MSTRG.6365","AC055839.1","ENST00000634467","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000278685","IQCA1L","ENST00000615129","GO:0005524(ATP binding)","NA","NA","NA","IQ motif containing with AAA domain 1 like [Source:HGNC Symbol;Acc:HGNC:22831]",0,0,1,0,1,1,"no","no"]
["ENSG00000224367","OACYLP","ENST00000587906;ENST00000587790","NA","NA","NA","NA","O-acyltransferase like, pseudogene [Source:HGNC Symbol;Acc:HGNC:44362]",0,{"v":0.0282294930511687,"d":"0.03"},"-inf","-inf",1,1,"down","no"]
["ENSG00000259171","AL163636.2","ENST00000553909","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000237451","CDK2AP2P2","ENST00000478512","NA","NA","NA","NA","cyclin dependent kinase 2 associated protein 2 pseudogene 2 [Source:HGNC Symbol;Acc:HGNC:38493]",0,0,1,0,1,1,"no","no"]
["MSTRG.701","AC099568.1","ENST00000432395","NA","NA","NA","NA",null,{"v":0.504932,"d":"0.50"},0,"inf","inf",1,1,"up","no"]
["ENSG00000228283","KATNBL1P6","ENST00000562413","NA","NA","NA","NA","katanin regulatory subunit B1 like 1 pseudogene 6 [Source:HGNC Symbol;Acc:HGNC:49056]",0,{"v":0.022563,"d":"0.02"},"-inf","-inf",1,1,"down","no"]
["ENSG00000274678","AC106886.3","ENST00000621583","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000149506","ZP1","ENST00000278853;ENST00000537203","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005886(plasma membrane);GO:0005576(extracellular region);GO:0005578(proteinaceous extracellular matrix);GO:0007338(single fertilization);GO:0007339(binding of sperm to zona pellucida);GO:0005794(Golgi apparatus);GO:0030141(secretory granule);GO:0031012(extracellular matrix);GO:0031012(extracellular matrix)","NA","NA","NA","zona pellucida glycoprotein 1 [Source:HGNC Symbol;Acc:HGNC:13187]",{"v":0.124464024630542,"d":"0.12"},{"v":0.0287316990968801,"d":"0.03"},{"v":4.33194097609275,"d":"4.33"},{"v":2.11501358595677,"d":"2.12"},1,1,"up","no"]
["ENSG00000223561","AC005165.1","ENST00000446840","NA","NA","NA","NA",null,{"v":0.100333564690027,"d":"0.10"},0,"inf","inf",1,1,"up","no"]
["ENSG00000124490","CRISP2","ENST00000616725;ENST00000618917","GO:0005576(extracellular region);GO:0005615(extracellular space);GO:0005615(extracellular space)","NA","NA","NA","cysteine rich secretory protein 2 [Source:HGNC Symbol;Acc:HGNC:12024]",{"v":0.0661431778656127,"d":"0.07"},{"v":0.1495744743083,"d":"0.15"},{"v":0.442208994358754,"d":"0.44"},{"v":-1.17719972557943,"d":"-1.18"},1,1,"down","no"]
["ENSG00000259589","AC073167.1","ENST00000559303","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000174776","WDR49","ENST00000472600;ENST00000479765;ENST00000308378","GO:0005509(calcium ion binding);GO:0005509(calcium ion binding)","NA","NA","NA","WD repeat domain 49 [Source:HGNC Symbol;Acc:HGNC:26587]",{"v":0.0741844459007967,"d":"0.07"},{"v":0.12307843536366,"d":"0.12"},{"v":0.602741216863895,"d":"0.60"},{"v":-0.730389371837205,"d":"-0.73"},1,1,"down","no"]
["ENSG00000224616","RTCA-AS1","ENST00000421185","NA","NA","NA","NA","RTCA antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:50573]",{"v":1.453683,"d":"1.45"},{"v":1.31768,"d":"1.32"},{"v":1.10321398215045,"d":"1.10"},{"v":0.141712646818845,"d":"0.14"},1,1,"up","no"]
["ENSG00000282828","AC009971.1","ENST00000634253","NA","NA","NA","NA",null,{"v":0.519993,"d":"0.52"},{"v":0.380538,"d":"0.38"},{"v":1.36646800056762,"d":"1.37"},{"v":0.45045167576822,"d":"0.45"},1,1,"up","no"]
["ENSG00000166510","CCDC68","ENST00000337363;ENST00000591504","GO:0005515(protein binding);GO:0005515(protein binding)","NA","NA","NA","coiled-coil domain containing 68 [Source:HGNC Symbol;Acc:HGNC:24350]",{"v":0.00560771428571429,"d":"0.01"},{"v":0.0152836138996139,"d":"0.02"},{"v":0.366910229645094,"d":"0.37"},{"v":-1.44650096666364,"d":"-1.45"},1,1,"down","no"]
["MSTRG.8403","AC245052.4","ENST00000452097","NA","NA","NA","NA",null,{"v":0.283384,"d":"0.28"},{"v":0.025553,"d":"0.03"},{"v":11.0900481352483,"d":"11.09"},{"v":3.47119372227457,"d":"3.47"},1,1,"up","no"]
["ENSG00000175183","CSRP2","ENST00000548783","GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0005515(protein binding);GO:0007275(multicellular organism development);GO:0030154(cell differentiation);GO:0005925(focal adhesion);GO:0003674(molecular_function)","NA","NA","NA","cysteine and glycine rich protein 2 [Source:HGNC Symbol;Acc:HGNC:2470]",{"v":0.00875183313468415,"d":"0.01"},0,"inf","inf",1,1,"up","no"]
["ENSG00000270073","TSPY6P","ENST00000448518","NA","NA","NA","NA","testis specific protein, Y-linked 6, pseudogene [Source:HGNC Symbol;Acc:HGNC:34039]",0,{"v":2.562E-3,"d":"0.00"},"-inf","-inf",1,1,"down","no"]
["ENSG00000261369","AC007533.1","ENST00000564739","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000230442","AC006333.1","ENST00000422401","NA","NA","NA","NA",null,{"v":0.0138649797336422,"d":"0.01"},0,"inf","inf",1,1,"up","no"]
["ENSG00000147113","CXorf36","ENST00000398000","GO:0005576(extracellular region);GO:0009966(regulation of signal transduction)","NA","NA","NA","chromosome X open reading frame 36 [Source:HGNC Symbol;Acc:HGNC:25866]",{"v":0.0440590208333333,"d":"0.04"},{"v":0.0301328125,"d":"0.03"},{"v":1.46216091954023,"d":"1.46"},{"v":0.548102097232227,"d":"0.55"},1,1,"up","no"]
["ENSG00000225986","UBXN10-AS1","ENST00000442226","NA","NA","NA","NA","UBXN10 antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:41141]",0,0,1,0,1,1,"no","no"]
["ENSG00000112964","GHR","ENST00000615111;ENST00000511135","GO:0005615(extracellular space);GO:0042531(positive regulation of tyrosine phosphorylation of STAT protein);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0004896(cytokine receptor activity);GO:0019221(cytokine-mediated signaling pathway);GO:0000932(P-body);GO:0006897(endocytosis);GO:0042803(protein homodimerization activity);GO:0009986(cell surface);GO:0050731(positive regulation of peptidyl-tyrosine phosphorylation);GO:0000187(activation of MAPK activity);GO:0032870(cellular response to hormone stimulus);GO:0060396(growth hormone receptor signaling pathway);GO:0019901(protein kinase binding);GO:0043235(receptor complex);GO:0005887(integral component of plasma membrane);GO:0060397(JAK-STAT cascade involved in growth hormone signaling pathway);GO:0040014(regulation of multicellular organism growth);GO:0007259(JAK-STAT cascade);GO:0040018(positive regulation of multicellular organism growth);GO:0070195(growth hormone receptor complex);GO:0017046(peptide hormone binding);GO:0070064(proline-rich region binding);GO:0000255(allantoin metabolic process);GO:0006101(citrate metabolic process);GO:0006103(2-oxoglutarate metabolic process);GO:0006105(succinate metabolic process);GO:0006107(oxaloacetate metabolic process);GO:0006549(isoleucine metabolic process);GO:0006573(valine metabolic process);GO:0006600(creatine metabolic process);GO:0006631(fatty acid metabolic process);GO:0019530(taurine metabolic process);GO:0042976(activation of Janus kinase activity);GO:0044236(multicellular organism metabolic process);GO:0046449(creatinine metabolic process);GO:0048009(insulin-like growth factor receptor signaling pathway);GO:0004903(growth hormone receptor activity);GO:0019903(protein phosphatase binding);GO:0042169(SH2 domain binding);GO:0009725(response to hormone);GO:0009755(hormone-mediated signaling pathway);GO:0032094(response to food);GO:0032869(cellular response to insulin stimulus);GO:0034097(response to cytokine);GO:0043278(response to morphine);GO:0043434(response to peptide hormone);GO:0045597(positive regulation of cell differentiation);GO:0046427(positive regulation of JAK-STAT cascade);GO:0051384(response to glucocorticoid);GO:0060351(cartilage development involved in endochondral bone morphogenesis);GO:0060416(response to growth hormone);GO:0070555(response to interleukin-1);GO:1901215(negative regulation of neuron death);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005739(mitochondrion);GO:0043025(neuronal cell body);GO:0043025(neuronal cell body)","04630(Jak-STAT signaling pathway);04151(PI3K-Akt signaling pathway);04080(Neuroactive ligand-receptor interaction);04060(Cytokine-cytokine receptor interaction);04060(Cytokine-cytokine receptor interaction)","K05080","NA","growth hormone receptor [Source:HGNC Symbol;Acc:HGNC:4263]",{"v":4.94645007564297E-3,"d":"0.00"},{"v":0.00246744810892587,"d":"0.00"},{"v":2.00468251297745,"d":"2.00"},{"v":1.00337377123314,"d":"1.00"},1,1,"up","no"]
["MSTRG.5614","VASN","ENST00000304735","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005765(lysosomal membrane);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0005615(extracellular space);GO:0005886(plasma membrane);GO:0045296(cadherin binding);GO:0070062(extracellular exosome);GO:0009986(cell surface);GO:0010719(negative regulation of epithelial to mesenchymal transition);GO:0030512(negative regulation of transforming growth factor beta receptor signaling pathway);GO:0050431(transforming growth factor beta binding);GO:0071456(cellular response to hypoxia);GO:0071461(cellular response to redox state);GO:0005739(mitochondrion)","NA","NA","NA","vasorin [Source:HGNC Symbol;Acc:HGNC:18517]",{"v":0.073763,"d":"0.07"},{"v":0.202863,"d":"0.20"},{"v":0.363609923938816,"d":"0.36"},{"v":-1.45953651960745,"d":"-1.46"},1,1,"down","no"]
["MSTRG.7967","AC010319.3","ENST00000597028","NA","NA","NA","NA",null,0,{"v":0.291216,"d":"0.29"},"-inf","-inf",1,1,"down","no"]
["ENSG00000131044","TTLL9","ENST00000535842;ENST00000375921;ENST00000620043","GO:0005737(cytoplasm);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0006464(cellular protein modification process);GO:0005856(cytoskeleton);GO:0042995(cell projection);GO:0016874(ligase activity);GO:0005874(microtubule);GO:0005929(cilium);GO:0003824(catalytic activity);GO:0003824(catalytic activity)","NA","NA","NA","tubulin tyrosine ligase like 9 [Source:HGNC Symbol;Acc:HGNC:16118]",{"v":0.0454183399156118,"d":"0.05"},{"v":0.00565974683544304,"d":"0.01"},{"v":8.02480062026599,"d":"8.02"},{"v":3.00446554828145,"d":"3.00"},1,1,"up","no"]
["ENSG00000140986","RPL3L","ENST00000268661","GO:0016020(membrane);GO:0006412(translation);GO:0030529(intracellular ribonucleoprotein complex);GO:0005622(intracellular);GO:0003735(structural constituent of ribosome);GO:0005840(ribosome);GO:0000027(ribosomal large subunit assembly);GO:0003723(RNA binding);GO:0022625(cytosolic large ribosomal subunit)","03010(Ribosome)","K02925","NA","ribosomal protein L3 like [Source:HGNC Symbol;Acc:HGNC:10351]",{"v":0.0152597592458303,"d":"0.02"},{"v":0.032366860768673,"d":"0.03"},{"v":0.471462442863776,"d":"0.47"},{"v":-1.08478524583699,"d":"-1.08"},1,1,"down","no"]
["ENSG00000224743","TEX26-AS1","ENST00000586973;ENST00000585870","NA","NA","NA","NA","TEX26 antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:42784]",0,0,1,0,1,1,"no","no"]
["ENSG00000168631","DPCR1","ENST00000636043","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:1903955(positive regulation of protein targeting to mitochondrion)","NA","NA","NA","diffuse panbronchiolitis critical region 1 [Source:HGNC Symbol;Acc:HGNC:21666]",0,{"v":0.0401207956705385,"d":"0.04"},"-inf","-inf",1,1,"down","no"]
["MSTRG.52","FAM87B","ENST00000326734","NA","NA","NA","NA","family with sequence similarity 87 member B [Source:HGNC Symbol;Acc:HGNC:32236]",{"v":0.285479,"d":"0.29"},{"v":0.092482,"d":"0.09"},{"v":3.08686014575809,"d":"3.09"},{"v":1.62614012124528,"d":"1.63"},1,1,"up","no"]
["MSTRG.10929","RHOA-IT1","ENST00000428083","NA","NA","NA","NA","RHOA intronic transcript 1 [Source:HGNC Symbol;Acc:HGNC:41308]",0,{"v":0.088247,"d":"0.09"},"-inf","-inf",1,1,"down","no"]
["ENSG00000254432","AC113143.1","ENST00000534670","NA","NA","NA","NA",null,{"v":0.098016,"d":"0.10"},0,"inf","inf",1,1,"up","no"]
["ENSG00000112414","ADGRG6","ENST00000230173;ENST00000497898","GO:0005622(intracellular);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0004930(G-protein coupled receptor activity);GO:0007186(G-protein coupled receptor signaling pathway);GO:0005886(plasma membrane);GO:0004871(signal transducer activity);GO:0007165(signal transduction);GO:0004888(transmembrane signaling receptor activity);GO:0007166(cell surface receptor signaling pathway);GO:0043236(laminin binding);GO:0050840(extracellular matrix binding);GO:0019933(cAMP-mediated signaling);GO:0005518(collagen binding);GO:0042552(myelination);GO:0014037(Schwann cell differentiation);GO:0022011(myelination in peripheral nervous system);GO:0007005(mitochondrion organization);GO:0010579(positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway);GO:0060347(heart trabecula formation);GO:0060347(heart trabecula formation)","NA","NA","NA","adhesion G protein-coupled receptor G6 [Source:HGNC Symbol;Acc:HGNC:13841]",{"v":0.0588855585978992,"d":"0.06"},{"v":0.0315891369054644,"d":"0.03"},{"v":1.86410786638849,"d":"1.86"},{"v":0.898485343791148,"d":"0.90"},1,1,"up","no"]
["ENSG00000171224","C10orf35","ENST00000491890;ENST00000373279","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005515(protein binding);GO:0005515(protein binding)","NA","NA","NA","chromosome 10 open reading frame 35 [Source:HGNC Symbol;Acc:HGNC:23519]",{"v":0.315198157894737,"d":"0.32"},{"v":0.46922052631579,"d":"0.47"},{"v":0.671748442826232,"d":"0.67"},{"v":-0.574007022942894,"d":"-0.57"},1,1,"down","no"]
["ENSG00000121904","CSMD2","ENST00000619121;ENST00000373381;ENST00000338325","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005886(plasma membrane);GO:0005886(plasma membrane)","NA","NA","NA","CUB and Sushi multiple domains 2 [Source:HGNC Symbol;Acc:HGNC:19290]",{"v":0.0340699258688109,"d":"0.03"},{"v":0.0301796763782563,"d":"0.03"},{"v":1.12890295581027,"d":"1.13"},{"v":0.174921472657636,"d":"0.17"},1,1,"up","no"]
["ENSG00000123119","NECAB1","ENST00000417640","GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0005509(calcium ion binding)","NA","NA","NA","N-terminal EF-hand calcium binding protein 1 [Source:HGNC Symbol;Acc:HGNC:20983]",{"v":0.00195201076779026,"d":"0.00"},{"v":0.00662115449438202,"d":"0.01"},{"v":0.294814260782847,"d":"0.29"},{"v":-1.76212178258775,"d":"-1.76"},1,1,"down","no"]
["ENSG00000264424","MYH4","ENST00000255381","GO:0005737(cytoplasm);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0003774(motor activity);GO:0016459(myosin complex);GO:0003779(actin binding);GO:0005516(calmodulin binding);GO:0032982(myosin filament);GO:0030016(myofibril);GO:0003725(double-stranded RNA binding);GO:0000146(microfilament motor activity);GO:0030048(actin filament-based movement);GO:0016887(ATPase activity);GO:0046034(ATP metabolic process);GO:0006936(muscle contraction);GO:0030049(muscle filament sliding);GO:0005859(muscle myosin complex);GO:0030017(sarcomere);GO:0014823(response to activity)","04530(Tight junction)","K10352","NA","myosin heavy chain 4 [Source:HGNC Symbol;Acc:HGNC:7574]",{"v":0.008544,"d":"0.01"},{"v":0.016734,"d":"0.02"},{"v":0.510577267837935,"d":"0.51"},{"v":-0.969798788061914,"d":"-0.97"},1,1,"down","no"]
["ENSG00000225434","LINC01504","ENST00000451152;ENST00000451596;ENST00000436054","NA","NA","NA","NA","long intergenic non-protein coding RNA 1504 [Source:HGNC Symbol;Acc:HGNC:51185]",{"v":0.334950017900732,"d":"0.33"},{"v":0.147810219690806,"d":"0.15"},{"v":2.26608159166119,"d":"2.27"},{"v":1.18019980721571,"d":"1.18"},1,1,"up","no"]
["ENSG00000221649","MIR1233-1","ENST00000408722","NA","NA","NA","NA","microRNA 1233-1 [Source:HGNC Symbol;Acc:HGNC:33929]",0,{"v":0.10015,"d":"0.10"},"-inf","-inf",1,1,"down","no"]
["ENSG00000144460","NYAP2","ENST00000636099","GO:0005622(intracellular);GO:0005515(protein binding);GO:0048812(neuron projection morphogenesis);GO:0014065(phosphatidylinositol 3-kinase signaling)","NA","NA","NA","neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adaptor 2 [Source:HGNC Symbol;Acc:HGNC:29291]",{"v":0.030394,"d":"0.03"},{"v":0.034419,"d":"0.03"},{"v":0.883058775676225,"d":"0.88"},{"v":-0.179418629205471,"d":"-0.18"},1,1,"down","no"]
["MSTRG.5949","AC023825.2","ENST00000562970","NA","NA","NA","NA",null,{"v":0.097159,"d":"0.10"},{"v":0.192986,"d":"0.19"},{"v":0.503451027535676,"d":"0.50"},{"v":-0.990076645885908,"d":"-0.99"},1,1,"down","no"]
["ENSG00000081248","CACNA1S","ENST00000362061","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0055085(transmembrane transport);GO:0005216(ion channel activity);GO:0006811(ion transport);GO:0005244(voltage-gated ion channel activity);GO:0034765(regulation of ion transmembrane transport);GO:0006816(calcium ion transport);GO:0070588(calcium ion transmembrane transport);GO:0005245(voltage-gated calcium channel activity);GO:0005262(calcium channel activity);GO:0005891(voltage-gated calcium channel complex);GO:0006810(transport);GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0005516(calmodulin binding);GO:0042383(sarcolemma);GO:0031674(I band);GO:0030315(T-tubule);GO:0061337(cardiac conduction);GO:0008331(high voltage-gated calcium channel activity);GO:0086010(membrane depolarization during action potential);GO:0006936(muscle contraction);GO:0071313(cellular response to caffeine);GO:1990454(L-type voltage-gated calcium channel complex)","04010(MAPK signaling pathway);04020(Calcium signaling pathway);04024(cAMP signaling pathway);04022(cGMP - PKG signaling pathway);04911(Insulin secretion);04912(GnRH signaling pathway);04921(Oxytocin signaling pathway);04924(Renin secretion);04925(Aldosterone synthesis and secretion);04927(Cortisol synthesis and secretion);04260(Cardiac muscle contraction);04261(Adrenergic signaling in cardiomyocytes);04270(Vascular smooth muscle contraction);04727(GABAergic synapse);04725(Cholinergic synapse);04726(Serotonergic synapse);04723(Retrograde endocannabinoid signaling);05010(Alzheimer's disease);05410(Hypertrophic cardiomyopathy (HCM));05412(Arrhythmogenic right ventricular cardiomyopathy (ARVC));05414(Dilated cardiomyopathy (DCM))","K04857","NA","calcium voltage-gated channel subunit alpha1 S [Source:HGNC Symbol;Acc:HGNC:1397]",{"v":0.0302931741245136,"d":"0.03"},{"v":0.0471846952010376,"d":"0.05"},{"v":0.642012711864407,"d":"0.64"},{"v":-0.639326231866608,"d":"-0.64"},1,1,"down","no"]
["MSTRG.5257","PHBP20","ENST00000603694","NA","NA","NA","NA","prohibitin pseudogene 20 [Source:HGNC Symbol;Acc:HGNC:51553]",{"v":0.062839,"d":"0.06"},0,"inf","inf",1,1,"up","no"]
["ENSG00000280094","OR1B1","ENST00000623530","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0004930(G-protein coupled receptor activity);GO:0007186(G-protein coupled receptor signaling pathway);GO:0005886(plasma membrane);GO:0004871(signal transducer activity);GO:0007165(signal transduction);GO:0004984(olfactory receptor activity);GO:0007608(sensory perception of smell);GO:0050896(response to stimulus);GO:0050911(detection of chemical stimulus involved in sensory perception of smell);GO:0004888(transmembrane signaling receptor activity);GO:0050907(detection of chemical stimulus involved in sensory perception)","04740(Olfactory transduction)","K04257","NA","olfactory receptor family 1 subfamily B member 1 (gene/pseudogene) [Source:HGNC Symbol;Acc:HGNC:8181]",{"v":0.048044,"d":"0.05"},{"v":0.091706,"d":"0.09"},{"v":0.523891566527817,"d":"0.52"},{"v":-0.932659856828519,"d":"-0.93"},1,1,"down","no"]
["ENSG00000280385","AP000648.3","ENST00000623539","NA","NA","NA","NA",null,{"v":0.818532,"d":"0.82"},0,"inf","inf",1,1,"up","no"]
["ENSG00000205231","TTLL10-AS1","ENST00000379317","NA","NA","NA","NA","TTLL10 antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:41159]",{"v":0.009113,"d":"0.01"},{"v":0.021701,"d":"0.02"},{"v":0.419934565227409,"d":"0.42"},{"v":-1.25176355217809,"d":"-1.25"},1,1,"down","no"]
["MSTRG.6425","AC016876.1","ENST00000573187;ENST00000417897;ENST00000415124;ENST00000572046","NA","NA","NA","NA",null,{"v":0.180241287334594,"d":"0.18"},{"v":0.1575010463138,"d":"0.16"},{"v":1.14438152350739,"d":"1.14"},{"v":0.194568110079353,"d":"0.19"},1,1,"up","no"]
["ENSG00000070031","SCT","ENST00000176195","GO:0005576(extracellular region);GO:0005179(hormone activity);GO:0005575(cellular_component);GO:0005102(receptor binding);GO:0047485(protein N-terminus binding);GO:0007420(brain development);GO:0030157(pancreatic juice secretion);GO:0030819(positive regulation of cAMP biosynthetic process);GO:0048566(embryonic digestive tract development);GO:0090187(positive regulation of pancreatic juice secretion);GO:0090274(positive regulation of somatostatin secretion);GO:1903640(negative regulation of gastrin-induced gastric acid secretion);GO:0005615(extracellular space)","04080(Neuroactive ligand-receptor interaction);04972(Pancreatic secretion)","K05263","NA","secretin [Source:HGNC Symbol;Acc:HGNC:10607]",0,0,1,0,1,1,"no","no"]
["ENSG00000224072","AL139811.1","ENST00000424779","NA","NA","NA","NA",null,0,{"v":0.019845,"d":"0.02"},"-inf","-inf",1,1,"down","no"]
["MSTRG.13669","AC027644.2","ENST00000603786","NA","NA","NA","NA",null,{"v":0.214175,"d":"0.21"},0,"inf","inf",1,1,"up","no"]
["MSTRG.10248","MIF-AS1","ENST00000406213","NA","NA","NA","NA","MIF antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:27669]",{"v":0.372672,"d":"0.37"},{"v":0.51074,"d":"0.51"},{"v":0.72967067392411,"d":"0.73"},{"v":-0.45468262308503,"d":"-0.45"},1,1,"down","no"]
["ENSG00000221844","DPP3P2","ENST00000416030","NA","NA","NA","NA","dipeptidyl peptidase 3 pseudogene 2 [Source:HGNC Symbol;Acc:HGNC:51350]",{"v":0.030308,"d":"0.03"},0,"inf","inf",1,1,"up","no"]
["ENSG00000271717","AC022146.2","ENST00000605980","NA","NA","NA","NA",null,{"v":0.022648,"d":"0.02"},0,"inf","inf",1,1,"up","no"]
["MSTRG.697","FLJ27354","ENST00000415584;ENST00000526694;ENST00000528692;ENST00000443562","NA","NA","NA","NA","uncharacterized LOC400761 [Source:NCBI gene;Acc:400761]",{"v":0.447597327586207,"d":"0.45"},{"v":0.214019763409962,"d":"0.21"},{"v":2.09138315291387,"d":"2.09"},{"v":1.06445739582043,"d":"1.06"},1,1,"up","no"]
["ENSG00000144857","BOC","ENST00000466059","GO:0005887(integral component of plasma membrane);GO:0007411(axon guidance);GO:0007224(smoothened signaling pathway);GO:0045663(positive regulation of myoblast differentiation);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0007155(cell adhesion);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0051149(positive regulation of muscle cell differentiation);GO:0044295(axonal growth cone)","04340(Hedgehog signaling pathway);04360(Axon guidance)","NA","NA","BOC cell adhesion associated, oncogene regulated [Source:HGNC Symbol;Acc:HGNC:17173]",{"v":0.00950392061955469,"d":"0.01"},{"v":0.0281616408518877,"d":"0.03"},{"v":0.337477516652501,"d":"0.34"},{"v":-1.56713670441103,"d":"-1.57"},1,1,"down","no"]
["ENSG00000232818","RPS2P32","ENST00000439199","NA","NA","NA","NA","ribosomal protein S2 pseudogene 32 [Source:HGNC Symbol;Acc:HGNC:30518]",{"v":0.215135,"d":"0.22"},{"v":0.299385,"d":"0.30"},{"v":0.718589775706866,"d":"0.72"},{"v":-0.476759686463425,"d":"-0.48"},1,1,"down","no"]
["ENSG00000270558","AC025449.1","ENST00000603896","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000255222","SETP17","ENST00000534163","NA","NA","NA","NA","SET pseudogene 17 [Source:HGNC Symbol;Acc:HGNC:42936]",0,0,1,0,1,1,"no","no"]
["ENSG00000105711","SCN1B","ENST00000639260;ENST00000602150;ENST00000415950;ENST00000640135;ENST00000262631","GO:0060371(regulation of atrial cardiac muscle cell membrane depolarization);GO:0060307(regulation of ventricular cardiac muscle cell membrane repolarization);GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0007155(cell adhesion);GO:0005244(voltage-gated ion channel activity);GO:0006811(ion transport);GO:0034765(regulation of ion transmembrane transport);GO:0005886(plasma membrane);GO:0006814(sodium ion transport);GO:0005576(extracellular region);GO:0017080(sodium channel regulator activity);GO:0001518(voltage-gated sodium channel complex);GO:0005272(sodium channel activity);GO:0060078(regulation of postsynaptic membrane potential);GO:0005515(protein binding);GO:2000649(regulation of sodium ion transmembrane transporter activity);GO:0061337(cardiac conduction);GO:0007268(chemical synaptic transmission);GO:0007411(axon guidance);GO:0060048(cardiac muscle contraction);GO:0086002(cardiac muscle cell action potential involved in contraction);GO:0086091(regulation of heart rate by cardiac conduction);GO:0033268(node of Ranvier);GO:0086006(voltage-gated sodium channel activity involved in cardiac muscle cell action potential);GO:0035725(sodium ion transmembrane transport);GO:0086012(membrane depolarization during cardiac muscle cell action potential);GO:0030315(T-tubule);GO:0014704(intercalated disc);GO:0010976(positive regulation of neuron projection development);GO:0019871(sodium channel inhibitor activity);GO:0010765(positive regulation of sodium ion transport);GO:0019227(neuronal action potential propagation);GO:0051899(membrane depolarization);GO:0005248(voltage-gated sodium channel activity);GO:0086062(voltage-gated sodium channel activity involved in Purkinje myocyte action potential);GO:0021966(corticospinal neuron axon guidance);GO:0040011(locomotion);GO:0086047(membrane depolarization during Purkinje myocyte cell action potential);GO:0002028(regulation of sodium ion transport);GO:0046684(response to pyrethroid);GO:0034706(sodium channel complex);GO:0065009(regulation of molecular function);GO:0065009(regulation of molecular function)","04261(Adrenergic signaling in cardiomyocytes);04261(Adrenergic signaling in cardiomyocytes)","K04845","NA","sodium voltage-gated channel beta subunit 1 [Source:HGNC Symbol;Acc:HGNC:10586]",{"v":0.0677599109220568,"d":"0.07"},{"v":0.221058593144001,"d":"0.22"},{"v":0.3065246637027,"d":"0.31"},{"v":-1.70592493363029,"d":"-1.71"},1,1,"down","no"]
["ENSG00000205922","ONECUT3","ENST00000382349","GO:0005634(nucleus);GO:0006366(transcription from RNA polymerase II promoter);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0001077(transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0030154(cell differentiation);GO:0000977(RNA polymerase II regulatory region sequence-specific DNA binding);GO:0001228(transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0048731(system development);GO:0005667(transcription factor complex)","NA","NA","NA","one cut homeobox 3 [Source:HGNC Symbol;Acc:HGNC:13399]",{"v":0.003049,"d":"0.00"},{"v":3.62E-3,"d":"0.00"},{"v":0.842265193370166,"d":"0.84"},{"v":-0.247653546960819,"d":"-0.25"},1,1,"down","no"]
["ENSG00000215441","CTAGE12P","ENST00000400348","NA","NA","NA","NA","CTAGE family member 12, pseudogene [Source:HGNC Symbol;Acc:HGNC:37297]",{"v":0.062187,"d":"0.06"},0,"inf","inf",1,1,"up","no"]
["MSTRG.4695","LINC00677","ENST00000558224","NA","NA","NA","NA","long intergenic non-protein coding RNA 677 [Source:HGNC Symbol;Acc:HGNC:20121]",{"v":0.33349752739726,"d":"0.33"},{"v":0.0104165445205479,"d":"0.01"},{"v":32.0161380522491,"d":"32.02"},{"v":5.00072738809778,"d":"5.00"},1,1,"up","no"]
["ENSG00000137860","SLC28A2","ENST00000347644;ENST00000559924","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005887(integral component of plasma membrane);GO:0005886(plasma membrane);GO:0005337(nucleoside transmembrane transporter activity);GO:0005415(nucleoside:sodium symporter activity);GO:1901642(nucleoside transmembrane transport);GO:0006139(nucleobase-containing compound metabolic process);GO:0015211(purine nucleoside transmembrane transporter activity);GO:0015860(purine nucleoside transmembrane transport);GO:0015860(purine nucleoside transmembrane transport)","NA","NA","NA","solute carrier family 28 member 2 [Source:HGNC Symbol;Acc:HGNC:11002]",{"v":0.00653413020030817,"d":"0.01"},{"v":0.00615493913713405,"d":"0.01"},{"v":1.06160760565224,"d":"1.06"},{"v":0.0862506117264244,"d":"0.09"},1,1,"up","no"]
["MSTRG.9847","AL109806.1","ENST00000623967","NA","NA","NA","NA",null,{"v":0.407345,"d":"0.41"},{"v":0.145987,"d":"0.15"},{"v":2.79028269640447,"d":"2.79"},{"v":1.48041129554543,"d":"1.48"},1,1,"up","no"]
["ENSG00000170801","HTRA3","ENST00000382512;ENST00000307358","GO:0016787(hydrolase activity);GO:0005576(extracellular region);GO:0008233(peptidase activity);GO:0006508(proteolysis);GO:0004252(serine-type endopeptidase activity);GO:0005520(insulin-like growth factor binding);GO:0001558(regulation of cell growth);GO:0008236(serine-type peptidase activity);GO:0005515(protein binding);GO:0004175(endopeptidase activity);GO:0030512(negative regulation of transforming growth factor beta receptor signaling pathway);GO:0030514(negative regulation of BMP signaling pathway);GO:0030514(negative regulation of BMP signaling pathway)","NA","NA","NA","HtrA serine peptidase 3 [Source:HGNC Symbol;Acc:HGNC:30406]",{"v":0.0736805835591689,"d":"0.07"},{"v":0.105705937669377,"d":"0.11"},{"v":0.697033536466269,"d":"0.70"},{"v":-0.520700024547422,"d":"-0.52"},1,1,"down","no"]
["ENSG00000183908","LRRC55","ENST00000497933","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0006811(ion transport);GO:0071805(potassium ion transmembrane transport);GO:0005886(plasma membrane);GO:0005615(extracellular space);GO:0005887(integral component of plasma membrane);GO:0044325(ion channel binding);GO:0007409(axonogenesis);GO:0005578(proteinaceous extracellular matrix);GO:0005249(voltage-gated potassium channel activity);GO:0008076(voltage-gated potassium channel complex);GO:0099104(potassium channel activator activity);GO:1903818(positive regulation of voltage-gated potassium channel activity)","NA","NA","NA","leucine rich repeat containing 55 [Source:HGNC Symbol;Acc:HGNC:32324]",{"v":0.019003,"d":"0.02"},{"v":0.018722,"d":"0.02"},{"v":1.01500908022647,"d":"1.02"},{"v":0.0214926337543968,"d":"0.02"},1,1,"up","no"]
["ENSG00000203818","HIST2H3PS2","ENST00000392948","GO:0005634(nucleus);GO:0003677(DNA binding);GO:0046982(protein heterodimerization activity);GO:0000786(nucleosome);GO:0005694(chromosome);GO:0006334(nucleosome assembly);GO:0031492(nucleosomal DNA binding);GO:0003682(chromatin binding);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0000785(chromatin)","NA","NA","NA","histone cluster 2 H3 pseudogene 2 [Source:HGNC Symbol;Acc:HGNC:32060]",0,{"v":0.333021,"d":"0.33"},"-inf","-inf",1,1,"down","no"]
["ENSG00000204544","MUC21","ENST00000376296","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005886(plasma membrane);GO:0007162(negative regulation of cell adhesion);GO:0022408(negative regulation of cell-cell adhesion);GO:0070062(extracellular exosome);GO:0002223(stimulatory C-type lectin receptor signaling pathway);GO:0005796(Golgi lumen);GO:0016266(O-glycan processing)","NA","NA","NA","mucin 21, cell surface associated [Source:HGNC Symbol;Acc:HGNC:21661]",{"v":0.0331564318481413,"d":"0.03"},{"v":0.0360855098866333,"d":"0.04"},{"v":0.918829523326841,"d":"0.92"},{"v":-0.122130881540129,"d":"-0.12"},1,1,"down","no"]
["ENSG00000251555","AC096711.2","ENST00000510592","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000157680","DGKI","ENST00000453654;ENST00000424189","GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0005654(nucleoplasm);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0008152(metabolic process);GO:0003951(NAD+ kinase activity);GO:0004143(diacylglycerol kinase activity);GO:0007205(protein kinase C-activating G-protein coupled receptor signaling pathway);GO:0005737(cytoplasm);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0035556(intracellular signal transduction);GO:0005515(protein binding);GO:0005886(plasma membrane);GO:0043234(protein complex);GO:0030168(platelet activation);GO:0034260(negative regulation of GTPase activity);GO:0005095(GTPase inhibitor activity);GO:0017016(Ras GTPase binding);GO:0007269(neurotransmitter secretion);GO:0043087(regulation of GTPase activity);GO:0046579(positive regulation of Ras protein signal transduction);GO:0046834(lipid phosphorylation);GO:0046959(habituation);GO:0051966(regulation of synaptic transmission, glutamatergic);GO:0060079(excitatory postsynaptic potential);GO:1900452(regulation of long term synaptic depression);GO:0005829(cytosol);GO:0008021(synaptic vesicle);GO:0014069(postsynaptic density);GO:0032045(guanyl-nucleotide exchange factor complex);GO:0043025(neuronal cell body);GO:0043197(dendritic spine);GO:0043679(axon terminus);GO:0045202(synapse);GO:0048471(perinuclear region of cytoplasm);GO:0048786(presynaptic active zone);GO:0060076(excitatory synapse);GO:0097060(synaptic membrane);GO:0097060(synaptic membrane)","00561(Glycerolipid metabolism);00564(Glycerophospholipid metabolism);04070(Phosphatidylinositol signaling system);04072(Phospholipase D signaling pathway);05231(Choline metabolism in cancer);05231(Choline metabolism in cancer)","K00901","EC:2.7.1.107","diacylglycerol kinase iota [Source:HGNC Symbol;Acc:HGNC:2855]",{"v":0.00885895170107402,"d":"0.01"},{"v":0.0252008871310052,"d":"0.03"},{"v":0.351533327180957,"d":"0.35"},{"v":-1.50826662414017,"d":"-1.51"},1,1,"down","no"]
["ENSG00000131019","ULBP3","ENST00000367339;ENST00000438272","GO:0016020(membrane);GO:0005886(plasma membrane);GO:0031225(anchored component of membrane);GO:0050776(regulation of immune response);GO:0016032(viral process);GO:0030101(natural killer cell activation);GO:0046658(anchored component of plasma membrane);GO:0042267(natural killer cell mediated cytotoxicity);GO:0046703(natural killer cell lectin-like receptor binding);GO:0046703(natural killer cell lectin-like receptor binding)","04650(Natural killer cell mediated cytotoxicity);04650(Natural killer cell mediated cytotoxicity)","K07986","NA","UL16 binding protein 3 [Source:HGNC Symbol;Acc:HGNC:14895]",{"v":0.208715,"d":"0.21"},{"v":0.066484,"d":"0.07"},{"v":3.13932675530955,"d":"3.14"},{"v":1.6504551989521,"d":"1.65"},1,1,"up","no"]
["ENSG00000128917","DLL4","ENST00000557876;ENST00000249749;ENST00000559440","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005509(calcium ion binding);GO:0007275(multicellular organism development);GO:0005886(plasma membrane);GO:0007399(nervous system development);GO:0030154(cell differentiation);GO:0007219(Notch signaling pathway);GO:0007154(cell communication);GO:0050896(response to stimulus);GO:0005515(protein binding);GO:0010628(positive regulation of gene expression);GO:0008285(negative regulation of cell proliferation);GO:0007601(visual perception);GO:2000179(positive regulation of neural precursor cell proliferation);GO:0007165(signal transduction);GO:0010629(negative regulation of gene expression);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0030217(T cell differentiation);GO:0001525(angiogenesis);GO:0010596(negative regulation of endothelial cell migration);GO:0007220(Notch receptor processing);GO:0045747(positive regulation of Notch signaling pathway);GO:0035924(cellular response to vascular endothelial growth factor stimulus);GO:0044344(cellular response to fibroblast growth factor stimulus);GO:0090051(negative regulation of cell migration involved in sprouting angiogenesis);GO:0001569(branching involved in blood vessel morphogenesis);GO:0045746(negative regulation of Notch signaling pathway);GO:0061074(regulation of neural retina development);GO:0008015(blood circulation);GO:0061314(Notch signaling involved in heart development);GO:0001974(blood vessel remodeling);GO:0003208(cardiac ventricle morphogenesis);GO:0003209(cardiac atrium morphogenesis);GO:0003222(ventricular trabecula myocardium morphogenesis);GO:0035912(dorsal aorta morphogenesis);GO:0003344(pericardium morphogenesis);GO:0060579(ventral spinal cord interneuron fate commitment);GO:1903588(negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis);GO:0005112(Notch binding);GO:0043537(negative regulation of blood vessel endothelial cell migration);GO:0050767(regulation of neurogenesis);GO:0072554(blood vessel lumenization);GO:0072554(blood vessel lumenization)","04330(Notch signaling pathway);04658(Th1 and Th2 cell differentiation);05200(Pathways in cancer);05224(Breast cancer);01522(Endocrine resistance);01522(Endocrine resistance)","K06051","NA","delta like canonical Notch ligand 4 [Source:HGNC Symbol;Acc:HGNC:2910]",{"v":0.0481954971596886,"d":"0.05"},{"v":0.00838282179675994,"d":"0.01"},{"v":5.7493166773886,"d":"5.75"},{"v":2.52339049784404,"d":"2.52"},1,1,"up","no"]
["MSTRG.1599","STAM-AS1","ENST00000563601","NA","NA","NA","NA","STAM antisense RNA 1 (head to head) [Source:HGNC Symbol;Acc:HGNC:49568]",{"v":0.03955,"d":"0.04"},{"v":0.105489,"d":"0.11"},{"v":0.374920607835888,"d":"0.37"},{"v":-1.41534296809963,"d":"-1.42"},1,1,"down","no"]
["MSTRG.5584","AC006111.1","ENST00000573982","NA","NA","NA","NA",null,0,{"v":0.13775,"d":"0.14"},"-inf","-inf",1,1,"down","no"]
["ENSG00000184033","CTAG1B","ENST00000359887","GO:0005737(cytoplasm);GO:0005515(protein binding)","NA","NA","NA","cancer/testis antigen 1B [Source:HGNC Symbol;Acc:HGNC:2491]",{"v":0.064462,"d":"0.06"},0,"inf","inf",1,1,"up","no"]
["MSTRG.11225","AC133435.1","ENST00000498753","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["MSTRG.990","AL513523.2","ENST00000427283","NA","NA","NA","NA",null,{"v":0.0206081632653061,"d":"0.02"},0,"inf","inf",1,1,"up","no"]
["ENSG00000229212","AC044860.1","ENST00000560405;ENST00000558470;ENST00000559481;ENST00000560756;ENST00000560811","NA","NA","NA","NA",null,{"v":0.159118337788578,"d":"0.16"},{"v":0.121009352976914,"d":"0.12"},{"v":1.31492594476507,"d":"1.31"},{"v":0.39498155075053,"d":"0.39"},1,1,"up","no"]
["ENSG00000261377","PDCD6IPP2","ENST00000564604;ENST00000566178;ENST00000563202;ENST00000566321;ENST00000562423;ENST00000563144","NA","NA","NA","NA","PDCD6IP pseudogene 2 [Source:HGNC Symbol;Acc:HGNC:49873]",{"v":0.0360692383676583,"d":"0.04"},{"v":0.0252688541189931,"d":"0.03"},{"v":1.42741883734835,"d":"1.43"},{"v":0.513408716667692,"d":"0.51"},1,1,"up","no"]
["ENSG00000230295","GTF2IP23","ENST00000423746","NA","NA","NA","NA","general transcription factor IIi pseudogene 23 [Source:HGNC Symbol;Acc:HGNC:51735]",{"v":0.258719,"d":"0.26"},{"v":0.059352,"d":"0.06"},{"v":4.35906119423103,"d":"4.36"},{"v":2.12401745695962,"d":"2.12"},1,1,"up","no"]
["ENSG00000161958","FGF11","ENST00000575235;ENST00000293829","GO:0008083(growth factor activity);GO:0005576(extracellular region);GO:0007399(nervous system development);GO:0007165(signal transduction);GO:0007267(cell-cell signaling);GO:0007267(cell-cell signaling)","NA","NA","NA","fibroblast growth factor 11 [Source:HGNC Symbol;Acc:HGNC:3667]",{"v":0.0479965372866128,"d":"0.05"},0,"inf","inf",1,1,"up","no"]
["ENSG00000259410","AC009292.2","ENST00000560577","NA","NA","NA","NA",null,0,{"v":0.00303375561097257,"d":"0.00"},"-inf","-inf",1,1,"down","no"]
["ENSG00000274029","AC069209.1","ENST00000619282","NA","NA","NA","NA",null,0,{"v":0.279864,"d":"0.28"},"-inf","-inf",1,1,"down","no"]
["ENSG00000236403","AL353611.1","ENST00000417054","NA","NA","NA","NA",null,0,{"v":0.197506,"d":"0.20"},"-inf","-inf",1,1,"down","no"]
["MSTRG.999","AL358472.4","ENST00000633140","NA","NA","NA","NA",null,{"v":0.212848,"d":"0.21"},0,"inf","inf",1,1,"up","no"]
["ENSG00000268803","AC114797.1","ENST00000514003","NA","NA","NA","NA",null,0,{"v":0.056207,"d":"0.06"},"-inf","-inf",1,1,"down","no"]
["ENSG00000121853","GHSR","ENST00000427970","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0004930(G-protein coupled receptor activity);GO:0007186(G-protein coupled receptor signaling pathway);GO:0005886(plasma membrane);GO:0008154(actin polymerization or depolymerization);GO:0004871(signal transducer activity);GO:0007165(signal transduction);GO:0045121(membrane raft);GO:0009986(cell surface);GO:0050728(negative regulation of inflammatory response);GO:0043005(neuron projection);GO:0016520(growth hormone-releasing hormone receptor activity);GO:0008343(adult feeding behavior);GO:0032100(positive regulation of appetite);GO:0009725(response to hormone);GO:0046697(decidualization);GO:0042536(negative regulation of tumor necrosis factor biosynthetic process);GO:0001616(growth hormone secretagogue receptor activity);GO:0017046(peptide hormone binding);GO:0042562(hormone binding);GO:0007283(spermatogenesis);GO:0007565(female pregnancy);GO:0007611(learning or memory);GO:0009755(hormone-mediated signaling pathway);GO:0010700(negative regulation of norepinephrine secretion);GO:0030252(growth hormone secretion);GO:0032094(response to food);GO:0032099(negative regulation of appetite);GO:0032354(response to follicle-stimulating hormone);GO:0032355(response to estradiol);GO:0032691(negative regulation of interleukin-1 beta production);GO:0032869(cellular response to insulin stimulus);GO:0036321(ghrelin secretion);GO:0040018(positive regulation of multicellular organism growth);GO:0043134(regulation of hindgut contraction);GO:0043568(positive regulation of insulin-like growth factor receptor signaling pathway);GO:0045409(negative regulation of interleukin-6 biosynthetic process);GO:0045923(positive regulation of fatty acid metabolic process);GO:0045927(positive regulation of growth);GO:0046676(negative regulation of insulin secretion);GO:0051963(regulation of synapse assembly);GO:0051969(regulation of transmission of nerve impulse);GO:0060123(regulation of growth hormone secretion);GO:0060259(regulation of feeding behavior);GO:0060416(response to growth hormone);GO:0071222(cellular response to lipopolysaccharide);GO:0071548(response to dexamethasone);GO:0090327(negative regulation of locomotion involved in locomotory behavior);GO:0097067(cellular response to thyroid hormone stimulus);GO:0120058(-);GO:1903672(positive regulation of sprouting angiogenesis);GO:1904000(positive regulation of eating behavior);GO:1904008(response to monosodium glutamate);GO:1904349(positive regulation of small intestine smooth muscle contraction);GO:1904468(negative regulation of tumor necrosis factor secretion);GO:1905333(regulation of gastric motility);GO:1905564(positive regulation of vascular endothelial cell proliferation);GO:1990314(cellular response to insulin-like growth factor stimulus);GO:2000110(negative regulation of macrophage apoptotic process)","04024(cAMP signaling pathway);04080(Neuroactive ligand-receptor interaction)","K04284","NA","growth hormone secretagogue receptor [Source:HGNC Symbol;Acc:HGNC:4267]",0,{"v":0.071401695024077,"d":"0.07"},"-inf","-inf",1,1,"down","no"]
["ENSG00000253392","AC119403.1","ENST00000520090","NA","NA","NA","NA",null,{"v":0.045668,"d":"0.05"},{"v":0.034645,"d":"0.03"},{"v":1.31817001010247,"d":"1.32"},{"v":0.398536452981858,"d":"0.40"},1,1,"up","no"]
["MSTRG.2932","OAF","ENST00000534735","GO:0070062(extracellular exosome)","NA","NA","NA","out at first homolog [Source:HGNC Symbol;Acc:HGNC:28752]",{"v":0.05838,"d":"0.06"},{"v":0.168779,"d":"0.17"},{"v":0.345896112668045,"d":"0.35"},{"v":-1.53158929472393,"d":"-1.53"},1,1,"down","no"]
["ENSG00000198468","FLVCR1-AS1","ENST00000424044;ENST00000426161;ENST00000356684","NA","NA","NA","NA","FLVCR1 antisense RNA 1 (head to head) [Source:HGNC Symbol;Acc:HGNC:39077]",{"v":0.694940818681319,"d":"0.69"},{"v":0.0258100607627666,"d":"0.03"},{"v":26.9251911132203,"d":"26.93"},{"v":4.75088467984688,"d":"4.75"},1,1,"up","no"]
["ENSG00000184507","NUTM1","ENST00000614490","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005515(protein binding)","NA","NA","NA","NUT midline carcinoma family member 1 [Source:HGNC Symbol;Acc:HGNC:29919]",{"v":0.031373,"d":"0.03"},{"v":0.04692,"d":"0.05"},{"v":0.668648763853367,"d":"0.67"},{"v":-0.5806795218584,"d":"-0.58"},1,1,"down","no"]
["MSTRG.13355","LRP11;AL355312.2","ENST00000239367;ENST00000628047;ENST00000455607","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005886(plasma membrane);GO:0051219(phosphoprotein binding);GO:0009408(response to heat);GO:0009409(response to cold);GO:0009414(response to water deprivation);GO:0009612(response to mechanical stimulus);GO:0033555(multicellular organismal response to stress);GO:0035902(response to immobilization stress);GO:0042594(response to starvation)","NA","NA","NA","LDL receptor related protein 11 [Source:HGNC Symbol;Acc:HGNC:16936]",{"v":0.0423453989032372,"d":"0.04"},{"v":0.0409086860074297,"d":"0.04"},{"v":1.03511999616772,"d":"1.04"},{"v":0.0497980216776212,"d":"0.05"},1,1,"up","no"]
["MSTRG.8811","OR7E91P","ENST00000400027","NA","NA","NA","NA","olfactory receptor family 7 subfamily E member 91 pseudogene [Source:HGNC Symbol;Acc:HGNC:14747]",0,{"v":0.0380830367278798,"d":"0.04"},"-inf","-inf",1,1,"down","no"]
["ENSG00000250764","AC025178.1","ENST00000503441","NA","NA","NA","NA",null,{"v":0.061633,"d":"0.06"},0,"inf","inf",1,1,"up","no"]
["ENSG00000130294","KIF1A","ENST00000431776;ENST00000415042;ENST00000498729","GO:0005737(cytoplasm);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:1904115(axon cytoplasm);GO:0003777(microtubule motor activity);GO:0005856(cytoskeleton);GO:0008017(microtubule binding);GO:0005874(microtubule);GO:0007018(microtubule-based movement);GO:0016887(ATPase activity);GO:0003774(motor activity);GO:0005871(kinesin complex);GO:0008089(anterograde axonal transport);GO:0030424(axon);GO:0030424(axon)","NA","NA","NA","kinesin family member 1A [Source:HGNC Symbol;Acc:HGNC:888]",{"v":0.0202518701141054,"d":"0.02"},{"v":0.01861375600874,"d":"0.02"},{"v":1.08800556451886,"d":"1.09"},{"v":0.121685935157396,"d":"0.12"},1,1,"up","no"]
["MSTRG.6970","HOXB-AS1","ENST00000502764;ENST00000504972;ENST00000435312","NA","NA","NA","NA","HOXB cluster antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:43744]",{"v":0.220881125366139,"d":"0.22"},{"v":0.189917981839485,"d":"0.19"},{"v":1.16303429104898,"d":"1.16"},{"v":0.217893634039845,"d":"0.22"},1,1,"up","no"]
["ENSG00000268906","AC011473.3","ENST00000594910","NA","NA","NA","NA",null,0,{"v":0.09407,"d":"0.09"},"-inf","-inf",1,1,"down","no"]
["ENSG00000204960","BLACE","ENST00000378120","NA","NA","NA","NA","B-cell acute lymphoblastic leukemia expressed [Source:HGNC Symbol;Acc:HGNC:20484]",0,0,1,0,1,1,"no","no"]
["MSTRG.13435","GPR146","ENST00000481403;ENST00000427680;ENST00000474396;ENST00000444847;ENST00000397095","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0004930(G-protein coupled receptor activity);GO:0007186(G-protein coupled receptor signaling pathway);GO:0005886(plasma membrane);GO:0004871(signal transducer activity);GO:0007165(signal transduction);GO:0007165(signal transduction)","NA","NA","NA","G protein-coupled receptor 146 [Source:HGNC Symbol;Acc:HGNC:21718]",{"v":0.111001190506329,"d":"0.11"},{"v":1.05748444082278,"d":"1.06"},{"v":0.104967209181786,"d":"0.10"},{"v":-3.2519893816552,"d":"-3.25"},1,1,"down","no"]
["MSTRG.2190","OR52N1","ENST00000317078","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0007186(G-protein coupled receptor signaling pathway);GO:0005886(plasma membrane);GO:0004871(signal transducer activity);GO:0007165(signal transduction);GO:0004930(G-protein coupled receptor activity);GO:0004984(olfactory receptor activity);GO:0007608(sensory perception of smell);GO:0050896(response to stimulus);GO:0050911(detection of chemical stimulus involved in sensory perception of smell)","04740(Olfactory transduction)","K04257","NA","olfactory receptor family 52 subfamily N member 1 [Source:HGNC Symbol;Acc:HGNC:14853]",{"v":0.0201972695481336,"d":"0.02"},0,"inf","inf",1,1,"up","no"]
["MSTRG.1200","PIGC","ENST00000484368;ENST00000344529;ENST00000465374;ENST00000367728;ENST00000489002;ENST00000478184;ENST00000475059","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016740(transferase activity);GO:0016757(transferase activity, transferring glycosyl groups);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0006506(GPI anchor biosynthetic process);GO:0017176(phosphatidylinositol N-acetylglucosaminyltransferase activity);GO:0003824(catalytic activity);GO:0016254(preassembly of GPI anchor in ER membrane);GO:0000506(glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex);GO:0000506(glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex)","00563(Glycosylphosphatidylinositol(GPI)-anchor biosynthesis);00563(Glycosylphosphatidylinositol(GPI)-anchor biosynthesis)","K03859","NA","phosphatidylinositol glycan anchor biosynthesis class C [Source:HGNC Symbol;Acc:HGNC:8960]",{"v":2.20793450009569,"d":"2.21"},{"v":2.24664040382775,"d":"2.25"},{"v":0.982771651544184,"d":"0.98"},{"v":-0.0250718517237922,"d":"-0.03"},1,1,"down","no"]
["MSTRG.14106","TRBV25-1","ENST00000390398","NA","NA","NA","NA","T-cell receptor beta variable 25-1 [Source:HGNC Symbol;Acc:HGNC:12205]",{"v":1.154859,"d":"1.15"},{"v":0.544054,"d":"0.54"},{"v":2.12269186514574,"d":"2.12"},{"v":1.08589496149757,"d":"1.09"},1,1,"up","no"]
["ENSG00000267627","AC118757.1","ENST00000586982","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000165259","HDX","ENST00000297977;ENST00000373177;ENST00000472135;ENST00000449553;ENST00000506585","GO:0005634(nucleus);GO:0003677(DNA binding);GO:0003677(DNA binding)","NA","NA","NA","highly divergent homeobox [Source:HGNC Symbol;Acc:HGNC:26411]",{"v":0.0754244747864425,"d":"0.08"},{"v":0.178781758060072,"d":"0.18"},{"v":0.421880149322054,"d":"0.42"},{"v":-1.24509488869626,"d":"-1.25"},1,1,"down","no"]
["ENSG00000198553","KCNRG","ENST00000360473","GO:0005783(endoplasmic reticulum);GO:0051260(protein homooligomerization);GO:0042802(identical protein binding);GO:0005515(protein binding);GO:1902260(negative regulation of delayed rectifier potassium channel activity)","NA","NA","NA","potassium channel regulator [Source:HGNC Symbol;Acc:HGNC:18893]",{"v":0.0326637489230769,"d":"0.03"},{"v":0.0299081446153846,"d":"0.03"},{"v":1.09213558190015,"d":"1.09"},{"v":0.127151969071872,"d":"0.13"},1,1,"up","no"]
["ENSG00000232065","LINC01063","ENST00000441644","NA","NA","NA","NA","long intergenic non-protein coding RNA 1063 [Source:HGNC Symbol;Acc:HGNC:49092]",{"v":0.443121,"d":"0.44"},{"v":0.125575,"d":"0.13"},{"v":3.52873581524985,"d":"3.53"},{"v":1.81915142436648,"d":"1.82"},1,1,"up","no"]
["MSTRG.13546","AC007036.2","ENST00000415934","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000277058","HNRNPCL3","ENST00000617807","GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0005634(nucleus)","NA","NA","NA","heterogeneous nuclear ribonucleoprotein C-like 3 [Source:HGNC Symbol;Acc:HGNC:51235]",{"v":0.100744,"d":"0.10"},{"v":0.019871,"d":"0.02"},{"v":5.06990086055055,"d":"5.07"},{"v":2.34195753630347,"d":"2.34"},1,1,"up","no"]
["ENSG00000112232","KHDRBS2","ENST00000281156","GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0006397(mRNA processing);GO:0005634(nucleus);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0005515(protein binding);GO:0042802(identical protein binding);GO:0005654(nucleoplasm);GO:0017124(SH3 domain binding);GO:0008143(poly(A) binding);GO:0008266(poly(U) RNA binding);GO:0042169(SH2 domain binding);GO:0046982(protein heterodimerization activity);GO:0048024(regulation of mRNA splicing, via spliceosome)","NA","NA","NA","KH RNA binding domain containing, signal transduction associated 2 [Source:HGNC Symbol;Acc:HGNC:18114]",{"v":0.128285,"d":"0.13"},{"v":0.035635,"d":"0.04"},{"v":3.5999719377017,"d":"3.60"},{"v":1.84798566058373,"d":"1.85"},1,1,"up","no"]
["MSTRG.2459","AP001363.2","ENST00000538101","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000142789","CELA3A","ENST00000290122","GO:0016787(hydrolase activity);GO:0008233(peptidase activity);GO:0006508(proteolysis);GO:0004252(serine-type endopeptidase activity);GO:0008236(serine-type peptidase activity);GO:0005615(extracellular space);GO:0007586(digestion);GO:0008203(cholesterol metabolic process)","04972(Pancreatic secretion);04974(Protein digestion and absorption)","K01345","EC:3.4.21.70","chymotrypsin like elastase family member 3A [Source:HGNC Symbol;Acc:HGNC:15944]",{"v":0.0285876331699346,"d":"0.03"},{"v":0.0463443006535948,"d":"0.05"},{"v":0.61685326494871,"d":"0.62"},{"v":-0.697000748312274,"d":"-0.70"},1,1,"down","no"]
["ENSG00000121053","EPX","ENST00000225371","GO:0046872(metal ion binding);GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0020037(heme binding);GO:0098869(cellular oxidant detoxification);GO:0006952(defense response);GO:0005615(extracellular space);GO:0005576(extracellular region);GO:0004601(peroxidase activity);GO:0006979(response to oxidative stress);GO:0070062(extracellular exosome);GO:0042744(hydrogen peroxide catabolic process);GO:0043312(neutrophil degranulation);GO:0034774(secretory granule lumen);GO:0002215(defense response to nematode);GO:0032693(negative regulation of interleukin-10 production);GO:0032714(negative regulation of interleukin-5 production);GO:0032753(positive regulation of interleukin-4 production);GO:0072677(eosinophil migration)","05310(Asthma)","K10788","EC:1.11.1.7","eosinophil peroxidase [Source:HGNC Symbol;Acc:HGNC:3423]",{"v":0.093242,"d":"0.09"},{"v":0.059658,"d":"0.06"},{"v":1.56294210332227,"d":"1.56"},{"v":0.644264337008792,"d":"0.64"},1,1,"up","no"]
["ENSG00000231665","OGFOD1P1","ENST00000447552","NA","NA","NA","NA","2-oxoglutarate and iron dependent oxygenase domain containing 1 pseudogene 1 [Source:HGNC Symbol;Acc:HGNC:39202]",{"v":0.064575,"d":"0.06"},0,"inf","inf",1,1,"up","no"]
["ENSG00000169607","CKAP2L","ENST00000302450","GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005856(cytoskeleton);GO:0000922(spindle pole);GO:0005813(centrosome);GO:0072686(mitotic spindle)","NA","NA","NA","cytoskeleton associated protein 2 like [Source:HGNC Symbol;Acc:HGNC:26877]",{"v":0.0741626246407358,"d":"0.07"},{"v":0.0166198419237402,"d":"0.02"},{"v":4.4622942252417,"d":"4.46"},{"v":2.15778564206763,"d":"2.16"},1,1,"up","no"]
["ENSG00000003096","KLHL13","ENST00000371876;ENST00000540167","GO:0016567(protein ubiquitination);GO:0051301(cell division);GO:0007049(cell cycle);GO:0005829(cytosol);GO:0043687(post-translational protein modification);GO:0004842(ubiquitin-protein transferase activity);GO:0000910(cytokinesis);GO:0031463(Cul3-RING ubiquitin ligase complex);GO:0030496(midbody);GO:0030496(midbody)","04120(Ubiquitin mediated proteolysis);04120(Ubiquitin mediated proteolysis)","K10447","NA","kelch like family member 13 [Source:HGNC Symbol;Acc:HGNC:22931]",{"v":0.061807759272519,"d":"0.06"},{"v":0.0450818003723328,"d":"0.05"},{"v":1.37101355229928,"d":"1.37"},{"v":0.455242832049546,"d":"0.46"},1,1,"up","no"]
["ENSG00000248858","FLJ46284","ENST00000623616","NA","NA","NA","NA","uncharacterized LOC441369 [Source:NCBI gene;Acc:441369]",{"v":0.00564708313715773,"d":"0.01"},0,"inf","inf",1,1,"up","no"]
["MSTRG.10117","AC008132.1","ENST00000412938;ENST00000342005;ENST00000416498","NA","NA","NA","NA",null,{"v":0.0866433032904149,"d":"0.09"},{"v":0.0512892605020159,"d":"0.05"},{"v":1.68930693175055,"d":"1.69"},{"v":0.756431476561314,"d":"0.76"},1,1,"up","no"]
["MSTRG.1554","AL136320.1","ENST00000417273","NA","NA","NA","NA",null,{"v":0.072415,"d":"0.07"},{"v":0.043148,"d":"0.04"},{"v":1.67829331602855,"d":"1.68"},{"v":0.746994878232586,"d":"0.75"},1,1,"up","no"]
["ENSG00000232344","AC087163.2","ENST00000457299","NA","NA","NA","NA",null,{"v":0.571785,"d":"0.57"},{"v":0.316639,"d":"0.32"},{"v":1.80579461152922,"d":"1.81"},{"v":0.852633812099659,"d":"0.85"},1,1,"up","no"]
["ENSG00000219487","AL603766.1","ENST00000407763","NA","NA","NA","NA",null,{"v":0.173404,"d":"0.17"},{"v":0.034355,"d":"0.03"},{"v":5.04741667879494,"d":"5.05"},{"v":2.33554519018646,"d":"2.34"},1,1,"up","no"]
["ENSG00000267649","AC010327.4","ENST00000585911","NA","NA","NA","NA",null,{"v":0.0575994210526316,"d":"0.06"},{"v":0.0289309505389981,"d":"0.03"},{"v":1.9909273625486,"d":"1.99"},{"v":0.993440586401184,"d":"0.99"},1,1,"up","no"]
["ENSG00000228146","CASP16P","ENST00000576807;ENST00000428155;ENST00000575497","NA","NA","NA","NA","caspase 16, pseudogene [Source:HGNC Symbol;Acc:HGNC:27290]",{"v":0.0299860992433062,"d":"0.03"},{"v":0.0230653800931315,"d":"0.02"},{"v":1.30004791259588,"d":"1.30"},{"v":0.378564794015812,"d":"0.38"},1,1,"up","no"]
["MSTRG.5643","AC022167.1","ENST00000564919","NA","NA","NA","NA",null,0,{"v":0.070714,"d":"0.07"},"-inf","-inf",1,1,"down","no"]
["ENSG00000258645","HSPE1P2","ENST00000554777","NA","NA","NA","NA","heat shock protein family E (Hsp10) member 1 pseudogene 2 [Source:HGNC Symbol;Acc:HGNC:20052]",0,0,1,0,1,1,"no","no"]
["ENSG00000259838","ELOCP2","ENST00000566760","NA","NA","NA","NA","elongin C pseudogene 2 [Source:HGNC Symbol;Acc:HGNC:17762]",0,0,1,0,1,1,"no","no"]
["ENSG00000120235","IFNA6","ENST00000259555;ENST00000380210","GO:0005576(extracellular region);GO:0005125(cytokine activity);GO:0005615(extracellular space);GO:0006952(defense response);GO:0045087(innate immune response);GO:0005126(cytokine receptor binding);GO:0051607(defense response to virus);GO:0005575(cellular_component);GO:0019221(cytokine-mediated signaling pathway);GO:0060337(type I interferon signaling pathway);GO:0007596(blood coagulation);GO:0002250(adaptive immune response);GO:0005132(type I interferon receptor binding);GO:0002286(T cell activation involved in immune response);GO:0002323(natural killer cell activation involved in immune response);GO:0006959(humoral immune response);GO:0030183(B cell differentiation);GO:0033141(positive regulation of peptidyl-serine phosphorylation of STAT protein);GO:0042100(B cell proliferation);GO:0043330(response to exogenous dsRNA);GO:0060338(regulation of type I interferon-mediated signaling pathway);GO:0060338(regulation of type I interferon-mediated signaling pathway)","04630(Jak-STAT signaling pathway);04151(PI3K-Akt signaling pathway);04060(Cytokine-cytokine receptor interaction);04217(Necroptosis);04620(Toll-like receptor signaling pathway);04621(NOD-like receptor signaling pathway);04622(RIG-I-like receptor signaling pathway);04623(Cytosolic DNA-sensing pathway);04650(Natural killer cell mediated cytotoxicity);05200(Pathways in cancer);05320(Autoimmune thyroid disease);05152(Tuberculosis);05162(Measles);05164(Influenza A);05161(Hepatitis B);05160(Hepatitis C);05168(Herpes simplex infection);05167(Kaposi's sarcoma-associated herpesvirus infection);05165(Human papillomavirus infection);05165(Human papillomavirus infection)","K05414","NA","interferon alpha 6 [Source:HGNC Symbol;Acc:HGNC:5427]",0,{"v":0.0590983056994819,"d":"0.06"},"-inf","-inf",1,1,"down","no"]
["MSTRG.2348","ALKBH3-AS1","ENST00000499194;ENST00000527960","NA","NA","NA","NA","ALKBH3 antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:48670]",{"v":0.0215090548414739,"d":"0.02"},{"v":0.148483409597258,"d":"0.15"},{"v":0.14485830369746,"d":"0.14"},{"v":-2.78728570845106,"d":"-2.79"},1,1,"down","no"]
["ENSG00000196539","OR2T3","ENST00000359594","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0004930(G-protein coupled receptor activity);GO:0007186(G-protein coupled receptor signaling pathway);GO:0005886(plasma membrane);GO:0004871(signal transducer activity);GO:0007165(signal transduction);GO:0004984(olfactory receptor activity);GO:0007608(sensory perception of smell);GO:0050896(response to stimulus);GO:0050911(detection of chemical stimulus involved in sensory perception of smell)","04740(Olfactory transduction)","K04257","NA","olfactory receptor family 2 subfamily T member 3 [Source:HGNC Symbol;Acc:HGNC:14727]",0,{"v":0.020102,"d":"0.02"},"-inf","-inf",1,1,"down","no"]
["ENSG00000260625","AC026471.2","ENST00000569782","NA","NA","NA","NA",null,{"v":0.217409,"d":"0.22"},0,"inf","inf",1,1,"up","no"]
["ENSG00000272754","AL133245.1","ENST00000608925","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["MSTRG.6972","HOXB-AS2","ENST00000464382","NA","NA","NA","NA","HOXB cluster antisense RNA 2 [Source:HGNC Symbol;Acc:HGNC:40284]",0,{"v":0.120675,"d":"0.12"},"-inf","-inf",1,1,"down","no"]
["MSTRG.478","AC098484.1","ENST00000447572","NA","NA","NA","NA",null,{"v":0.15352,"d":"0.15"},{"v":0.260757,"d":"0.26"},{"v":0.588747377826866,"d":"0.59"},{"v":-0.764279365647465,"d":"-0.76"},1,1,"down","no"]
["ENSG00000204361","NXPE2","ENST00000389586","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005515(protein binding)","NA","NA","NA","neurexophilin and PC-esterase domain family member 2 [Source:HGNC Symbol;Acc:HGNC:26331]",0,{"v":0.022855,"d":"0.02"},"-inf","-inf",1,1,"down","no"]
["ENSG00000250061","AC091976.1","ENST00000509211;ENST00000458002","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000163554","SPTA1","ENST00000368147;ENST00000484520;ENST00000492934;ENST00000481212;ENST00000465741","GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0005509(calcium ion binding);GO:0003779(actin binding);GO:0051693(actin filament capping);GO:0043547(positive regulation of GTPase activity);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0005829(cytosol);GO:0005938(cell cortex);GO:0000165(MAPK cascade);GO:0008360(regulation of cell shape);GO:0015629(actin cytoskeleton);GO:0005200(structural constituent of cytoskeleton);GO:0007411(axon guidance);GO:0006888(ER to Golgi vesicle-mediated transport);GO:0005088(Ras guanyl-nucleotide exchange factor activity);GO:0008091(spectrin);GO:0046982(protein heterodimerization activity);GO:0051015(actin filament binding);GO:0002260(lymphocyte homeostasis);GO:0006779(porphyrin-containing compound biosynthetic process);GO:0007009(plasma membrane organization);GO:0007015(actin filament organization);GO:0030036(actin cytoskeleton organization);GO:0030097(hemopoiesis);GO:0032092(positive regulation of protein binding);GO:0042102(positive regulation of T cell proliferation);GO:0009898(cytoplasmic side of plasma membrane);GO:0014731(spectrin-associated cytoskeleton);GO:0016020(membrane);GO:0030424(axon);GO:0030863(cortical cytoskeleton);GO:0031235(intrinsic component of the cytoplasmic side of the plasma membrane);GO:0032437(cuticular plate);GO:0032437(cuticular plate)","04210(Apoptosis);04210(Apoptosis)","K06114","NA","spectrin alpha, erythrocytic 1 [Source:HGNC Symbol;Acc:HGNC:11272]",{"v":0.317872086184539,"d":"0.32"},{"v":0.323713213067332,"d":"0.32"},{"v":0.981955858930052,"d":"0.98"},{"v":-0.0262699211966982,"d":"-0.03"},1,1,"down","no"]
["ENSG00000267943","AC010328.1","ENST00000596769","NA","NA","NA","NA",null,{"v":0.011226,"d":"0.01"},{"v":0.021351,"d":"0.02"},{"v":0.525783335675144,"d":"0.53"},{"v":-0.927459677389021,"d":"-0.93"},1,1,"down","no"]
["ENSG00000239810","PRAMEF11","ENST00000619922","GO:0043066(negative regulation of apoptotic process);GO:0008284(positive regulation of cell proliferation);GO:0045596(negative regulation of cell differentiation);GO:0045892(negative regulation of transcription, DNA-templated)","NA","NA","NA","PRAME family member 11 [Source:HGNC Symbol;Acc:HGNC:14086]",{"v":0.006965,"d":"0.01"},{"v":0.013655,"d":"0.01"},{"v":0.5100695715855,"d":"0.51"},{"v":-0.971234056164033,"d":"-0.97"},1,1,"down","no"]
["MSTRG.7533","AC098848.1","ENST00000588466","NA","NA","NA","NA",null,0,{"v":0.03625,"d":"0.04"},"-inf","-inf",1,1,"down","no"]
["ENSG00000284584","MIR5006","ENST00000583027","NA","NA","NA","NA","microRNA 5006 [Source:HGNC Symbol;Acc:HGNC:43495]",0,0,1,0,1,1,"no","no"]
["ENSG00000175097","RAG2","ENST00000618712","GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0016569(covalent chromatin modification);GO:0003677(DNA binding);GO:0016567(protein ubiquitination);GO:0008270(zinc ion binding);GO:0006310(DNA recombination);GO:0035091(phosphatidylinositol binding);GO:0005654(nucleoplasm);GO:0080025(phosphatidylinositol-3,5-bisphosphate binding);GO:0003682(chromatin binding);GO:0005546(phosphatidylinositol-4,5-bisphosphate binding);GO:0005547(phosphatidylinositol-3,4,5-trisphosphate binding);GO:0043325(phosphatidylinositol-3,4-bisphosphate binding);GO:0035064(methylated histone binding);GO:0030183(B cell differentiation);GO:0033151(V(D)J recombination);GO:0002331(pre-B cell allelic exclusion);GO:0033077(T cell differentiation in thymus);GO:0061630(ubiquitin protein ligase activity);GO:0002326(B cell lineage commitment);GO:0002358(B cell homeostatic proliferation);GO:0002360(T cell lineage commitment);GO:0030217(T cell differentiation);GO:0042742(defense response to bacterium);GO:0046622(positive regulation of organ growth)","04068(FoxO signaling pathway);05340(Primary immunodeficiency)","K10988","NA","recombination activating 2 [Source:HGNC Symbol;Acc:HGNC:9832]",0,{"v":0.0260556367789834,"d":"0.03"},"-inf","-inf",1,1,"down","no"]
["MSTRG.10352","AC005529.1","ENST00000411969","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000248677","LINC02102","ENST00000503989","NA","NA","NA","NA","long intergenic non-protein coding RNA 2102 [Source:HGNC Symbol;Acc:HGNC:52957]",0,{"v":0.013562,"d":"0.01"},"-inf","-inf",1,1,"down","no"]
["ENSG00000254245","PCDHGA3","ENST00000619750","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005509(calcium ion binding);GO:0007155(cell adhesion);GO:0007156(homophilic cell adhesion via plasma membrane adhesion molecules);GO:0005886(plasma membrane);GO:0005887(integral component of plasma membrane);GO:0007399(nervous system development);GO:0007267(cell-cell signaling);GO:0008333(endosome to lysosome transport);GO:0060989(lipid tube assembly involved in organelle fusion)","NA","NA","NA","protocadherin gamma subfamily A, 3 [Source:HGNC Symbol;Acc:HGNC:8701]",0,{"v":0.00879522867104184,"d":"0.01"},"-inf","-inf",1,1,"down","no"]
["MSTRG.702","AC099568.2","ENST00000609194","NA","NA","NA","NA",null,{"v":0.294606,"d":"0.29"},{"v":0.380746,"d":"0.38"},{"v":0.773759934444485,"d":"0.77"},{"v":-0.370042067417604,"d":"-0.37"},1,1,"down","no"]
["ENSG00000283646","LINC02009","ENST00000635852","NA","NA","NA","NA","long intergenic non-protein coding RNA 2009 [Source:HGNC Symbol;Acc:HGNC:52845]",{"v":0.136851,"d":"0.14"},{"v":0.0405,"d":"0.04"},{"v":3.37903703703704,"d":"3.38"},{"v":1.7566121637177,"d":"1.76"},1,1,"up","no"]
["MSTRG.13555","NANOGP4","ENST00000427230","NA","NA","NA","NA","Nanog homeobox pseudogene 4 [Source:HGNC Symbol;Acc:HGNC:23102]",{"v":0.0563,"d":"0.06"},0,"inf","inf",1,1,"up","no"]
["ENSG00000272597","AC063944.3","ENST00000609969","NA","NA","NA","NA",null,0,{"v":0.081318,"d":"0.08"},"-inf","-inf",1,1,"down","no"]
["ENSG00000255420","CASC23","ENST00000534076","NA","NA","NA","NA","cancer susceptibility 23 (non-protein coding) [Source:HGNC Symbol;Acc:HGNC:50865]",0,0,1,0,1,1,"no","no"]
["ENSG00000226125","LINC01907","ENST00000415174","NA","NA","NA","NA","long intergenic non-protein coding RNA 1907 [Source:HGNC Symbol;Acc:HGNC:52726]",{"v":0.039404,"d":"0.04"},{"v":0.087261,"d":"0.09"},{"v":0.451564845692807,"d":"0.45"},{"v":-1.14699491816254,"d":"-1.15"},1,1,"down","no"]
["ENSG00000224715","Z82186.1","ENST00000434707","NA","NA","NA","NA",null,{"v":0.010797,"d":"0.01"},0,"inf","inf",1,1,"up","no"]
["MSTRG.3168","AC022075.2","ENST00000535911","NA","NA","NA","NA",null,{"v":0.038678,"d":"0.04"},{"v":0.041951,"d":"0.04"},{"v":0.921980405711425,"d":"0.92"},{"v":-0.117192004626829,"d":"-0.12"},1,1,"down","no"]
["MSTRG.12691","AL009031.1","ENST00000632370;ENST00000632346","NA","NA","NA","NA",null,{"v":0.753483637672466,"d":"0.75"},{"v":0.241904580683863,"d":"0.24"},{"v":3.11479689860511,"d":"3.11"},{"v":1.63913809489357,"d":"1.64"},1,1,"up","no"]
["MSTRG.2115","RPL26P30","ENST00000602923;ENST00000453533","NA","NA","NA","NA","ribosomal protein L26 pseudogene 30 [Source:HGNC Symbol;Acc:HGNC:36733]",{"v":0.019923,"d":"0.02"},{"v":0.101976069767442,"d":"0.10"},{"v":0.195369365042551,"d":"0.20"},{"v":-2.35572383211619,"d":"-2.36"},1,1,"down","no"]
["ENSG00000261485","PAN3-AS1","ENST00000563843","NA","NA","NA","NA","PAN3 antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:39932]",{"v":1.09113,"d":"1.09"},0,"inf","inf",1,1,"up","no"]
["ENSG00000256463","SALL3","ENST00000537592","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0007165(signal transduction);GO:0043565(sequence-specific DNA binding);GO:0044212(transcription regulatory region DNA binding);GO:0006366(transcription from RNA polymerase II promoter);GO:0022008(neurogenesis);GO:0021891(olfactory bulb interneuron development);GO:0035136(forelimb morphogenesis);GO:0035137(hindlimb morphogenesis);GO:0045879(negative regulation of smoothened signaling pathway)","NA","NA","NA","spalt like transcription factor 3 [Source:HGNC Symbol;Acc:HGNC:10527]",{"v":0.0374389130728674,"d":"0.04"},{"v":0.0260489691766933,"d":"0.03"},{"v":1.43725123320292,"d":"1.44"},{"v":0.523312268625815,"d":"0.52"},1,1,"up","no"]
["ENSG00000145826","LECT2","ENST00000274507","GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0005576(extracellular region);GO:0006935(chemotaxis);GO:0042802(identical protein binding);GO:0005515(protein binding);GO:0005615(extracellular space);GO:0001501(skeletal system development)","NA","NA","NA","leukocyte cell derived chemotaxin 2 [Source:HGNC Symbol;Acc:HGNC:6550]",{"v":0.0456905489655172,"d":"0.05"},0,"inf","inf",1,1,"up","no"]
["ENSG00000273084","AC092171.5","ENST00000608012","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000274966","AC019322.3","ENST00000616104","NA","NA","NA","NA",null,{"v":0.070177,"d":"0.07"},{"v":0.017263,"d":"0.02"},{"v":4.06516827897816,"d":"4.07"},{"v":2.02331507437222,"d":"2.02"},1,1,"up","no"]
["MSTRG.5802","SPN","MSTRG.5802.1","NA","NA","NA","NA",null,{"v":1.546622,"d":"1.55"},{"v":0.644369,"d":"0.64"},{"v":2.40021167995357,"d":"2.40"},{"v":1.26316164589729,"d":"1.26"},1,1,"up","no"]
["MSTRG.13127","EEF1A1","MSTRG.13127.1","NA","NA","NA","NA",null,{"v":0.063772,"d":"0.06"},0,"inf","inf",1,1,"up","no"]
["ENSG00000172403","SYNPO2","ENST00000610556","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0043231(intracellular membrane-bounded organelle);GO:0005829(cytosol);GO:0003779(actin binding);GO:0015629(actin cytoskeleton);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0030054(cell junction);GO:0005925(focal adhesion);GO:0001725(stress fiber);GO:0030018(Z disc);GO:0071889(14-3-3 protein binding);GO:0031005(filamin binding);GO:0032233(positive regulation of actin filament bundle assembly);GO:0051393(alpha-actinin binding);GO:0051371(muscle alpha-actinin binding);GO:0000045(autophagosome assembly);GO:0099023(tethering complex)","NA","NA","NA","synaptopodin 2 [Source:HGNC Symbol;Acc:HGNC:17732]",{"v":0.0253702914350862,"d":"0.03"},{"v":0.015626114863902,"d":"0.02"},{"v":1.62358280711825,"d":"1.62"},{"v":0.699180967852992,"d":"0.70"},1,1,"up","no"]
["ENSG00000232145","AC099548.1","ENST00000421443","NA","NA","NA","NA",null,{"v":0.060331,"d":"0.06"},0,"inf","inf",1,1,"up","no"]
["ENSG00000258471","AL355922.2","ENST00000557335","NA","NA","NA","NA",null,{"v":0.055923,"d":"0.06"},{"v":0.108603,"d":"0.11"},{"v":0.514930526781028,"d":"0.51"},{"v":-0.957550294493428,"d":"-0.96"},1,1,"down","no"]
["ENSG00000224596","ZMIZ1-AS1","ENST00000456353;ENST00000440151","NA","NA","NA","NA","ZMIZ1 antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:27433]",{"v":0.0933680786085385,"d":"0.09"},{"v":0.0103061084255704,"d":"0.01"},{"v":9.05948926142517,"d":"9.06"},{"v":3.17942971905972,"d":"3.18"},1,1,"up","no"]
["ENSG00000232273","FTH1P1","ENST00000437933","NA","NA","NA","NA","ferritin heavy chain 1 pseudogene 1 [Source:HGNC Symbol;Acc:HGNC:3979]",{"v":0.09662,"d":"0.10"},0,"inf","inf",1,1,"up","no"]
["ENSG00000237706","TRIM51EP","ENST00000524374","NA","NA","NA","NA","tripartite motif-containing 51E, pseudogene [Source:HGNC Symbol;Acc:HGNC:43970]",{"v":0.033906,"d":"0.03"},{"v":0.060792,"d":"0.06"},{"v":0.557737860244769,"d":"0.56"},{"v":-0.842340887861735,"d":"-0.84"},1,1,"down","no"]
["MSTRG.3564","LINC01481","ENST00000552998","NA","NA","NA","NA","long intergenic non-protein coding RNA 1481 [Source:HGNC Symbol;Acc:HGNC:51126]",{"v":0.08172,"d":"0.08"},{"v":0.145068,"d":"0.15"},{"v":0.563322028290181,"d":"0.56"},{"v":-0.827968206687095,"d":"-0.83"},1,1,"down","no"]
["ENSG00000267004","AC018761.1","ENST00000591596","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000280228","AC079753.1","ENST00000623243","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000236463","LINC00427","ENST00000412722","NA","NA","NA","NA","long intergenic non-protein coding RNA 427 [Source:HGNC Symbol;Acc:HGNC:42762]",0,0,1,0,1,1,"no","no"]
["ENSG00000147381","MAGEA4","ENST00000370340;ENST00000370335","GO:0005515(protein binding);GO:0003674(molecular_function);GO:0008150(biological_process);GO:0005575(cellular_component);GO:0005575(cellular_component)","NA","NA","NA","MAGE family member A4 [Source:HGNC Symbol;Acc:HGNC:6802]",{"v":0.0117895004868549,"d":"0.01"},{"v":0.0444245550146056,"d":"0.04"},{"v":0.265382522863287,"d":"0.27"},{"v":-1.91385473174785,"d":"-1.91"},1,1,"down","no"]
["ENSG00000114638","UPK1B","ENST00000264234","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005887(integral component of plasma membrane);GO:0070062(extracellular exosome);GO:0007166(cell surface receptor signaling pathway);GO:0030855(epithelial cell differentiation);GO:0005198(structural molecule activity);GO:0016324(apical plasma membrane)","NA","NA","NA","uroplakin 1B [Source:HGNC Symbol;Acc:HGNC:12578]",0,{"v":0.00845611032656664,"d":"0.01"},"-inf","-inf",1,1,"down","no"]
["ENSG00000243806","RPL7P18","ENST00000478965","NA","NA","NA","NA","ribosomal protein L7 pseudogene 18 [Source:HGNC Symbol;Acc:HGNC:36949]",0,0,1,0,1,1,"no","no"]
["ENSG00000213921","LEUTX","ENST00000396841","GO:0005634(nucleus);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0043565(sequence-specific DNA binding)","NA","NA","NA","leucine twenty homeobox [Source:HGNC Symbol;Acc:HGNC:31953]",0,{"v":0.0364026470588235,"d":"0.04"},"-inf","-inf",1,1,"down","no"]
["MSTRG.3273","AC009509.4","ENST00000619202","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000258367","CR383656.14","ENST00000551951","NA","NA","NA","NA",null,{"v":0.017952,"d":"0.02"},0,"inf","inf",1,1,"up","no"]
["MSTRG.13549","AC005162.3","ENST00000608972","NA","NA","NA","NA",null,0,{"v":0.00934244711147274,"d":"0.01"},"-inf","-inf",1,1,"down","no"]
["ENSG00000223989","AL357140.1","ENST00000454104","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["MSTRG.6798","AC080112.4","ENST00000623156","NA","NA","NA","NA",null,0,{"v":0.036455,"d":"0.04"},"-inf","-inf",1,1,"down","no"]
["ENSG00000104055","TGM5","ENST00000220420","GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0016740(transferase activity);GO:0016746(transferase activity, transferring acyl groups);GO:0005886(plasma membrane);GO:0003810(protein-glutamine gamma-glutamyltransferase activity);GO:0018149(peptide cross-linking);GO:0006464(cellular protein modification process);GO:0008544(epidermis development);GO:0070268(cornification)","NA","NA","NA","transglutaminase 5 [Source:HGNC Symbol;Acc:HGNC:11781]",{"v":0.0333777471770862,"d":"0.03"},{"v":0.0261352332690719,"d":"0.03"},{"v":1.27711686494052,"d":"1.28"},{"v":0.352890547558924,"d":"0.35"},1,1,"up","no"]
["ENSG00000180998","GPR137C","ENST00000321662","GO:0016020(membrane);GO:0016021(integral component of membrane)","NA","NA","NA","G protein-coupled receptor 137C [Source:HGNC Symbol;Acc:HGNC:25445]",{"v":0.0234058478927822,"d":"0.02"},{"v":0.0118994270951074,"d":"0.01"},{"v":1.96697267067637,"d":"1.97"},{"v":0.975976912800188,"d":"0.98"},1,1,"up","no"]
["ENSG00000175170","FAM182B","ENST00000453481;ENST00000376403;ENST00000582267","NA","NA","NA","NA","family with sequence similarity 182 member B [Source:HGNC Symbol;Acc:HGNC:34503]",{"v":0.00284529320186819,"d":"0.00"},{"v":0.000789255838090296,"d":"0.00"},{"v":3.60503282275711,"d":"3.61"},{"v":1.85001239483734,"d":"1.85"},1,1,"up","no"]
["ENSG00000099866","MADCAM1","ENST00000613880;ENST00000619333;ENST00000617201;ENST00000622449;ENST00000215637;ENST00000346144;ENST00000587541","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0007155(cell adhesion);GO:0007229(integrin-mediated signaling pathway);GO:0050776(regulation of immune response);GO:0005886(plasma membrane);GO:0006955(immune response);GO:0007165(signal transduction);GO:0030198(extracellular matrix organization);GO:0043113(receptor clustering);GO:0007160(cell-matrix adhesion);GO:0034113(heterotypic cell-cell adhesion);GO:0050901(leukocyte tethering or rolling);GO:0098640(integrin binding involved in cell-matrix adhesion);GO:0002687(positive regulation of leukocyte migration);GO:0007568(aging);GO:0007568(aging)","04514(Cell adhesion molecules (CAMs));04672(Intestinal immune network for IgA production);04672(Intestinal immune network for IgA production)","K06779","NA","mucosal vascular addressin cell adhesion molecule 1 [Source:HGNC Symbol;Acc:HGNC:6765]",{"v":0.122796101848359,"d":"0.12"},{"v":0.207390745001886,"d":"0.21"},{"v":0.592100201227602,"d":"0.59"},{"v":-0.75608675082111,"d":"-0.76"},1,1,"down","no"]
["ENSG00000205015","LINC02138","ENST00000378340","NA","NA","NA","NA","long intergenic non-protein coding RNA 2138 [Source:HGNC Symbol;Acc:HGNC:52998]",{"v":0.074945,"d":"0.07"},0,"inf","inf",1,1,"up","no"]
["ENSG00000188295","ZNF669","ENST00000448299;ENST00000343381","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0005622(intracellular);GO:0005622(intracellular)","NA","NA","NA","zinc finger protein 669 [Source:HGNC Symbol;Acc:HGNC:25736]",{"v":0.143476370707071,"d":"0.14"},{"v":0.320958842424242,"d":"0.32"},{"v":0.447024202927005,"d":"0.45"},{"v":-1.16157515050899,"d":"-1.16"},1,1,"down","no"]
["ENSG00000218227","AC136632.1","ENST00000477964","NA","NA","NA","NA",null,{"v":0.294264,"d":"0.29"},{"v":0.631477,"d":"0.63"},{"v":0.465993219072112,"d":"0.47"},{"v":-1.10161913331728,"d":"-1.10"},1,1,"down","no"]
["ENSG00000226423","AC093642.1","ENST00000412193","NA","NA","NA","NA",null,0,{"v":0.073214,"d":"0.07"},"-inf","-inf",1,1,"down","no"]
["MSTRG.11943","AC093909.6","ENST00000624757","NA","NA","NA","NA",null,{"v":2.826449,"d":"2.83"},0,"inf","inf",1,1,"up","no"]
["ENSG00000263731","AC145207.5","ENST00000582866","NA","NA","NA","NA",null,{"v":0.182279,"d":"0.18"},{"v":0.22449,"d":"0.22"},{"v":0.811969352755134,"d":"0.81"},{"v":-0.30050282001706,"d":"-0.30"},1,1,"down","no"]
["ENSG00000181693","OR8H1","ENST00000313022","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0004930(G-protein coupled receptor activity);GO:0007186(G-protein coupled receptor signaling pathway);GO:0005886(plasma membrane);GO:0004871(signal transducer activity);GO:0007165(signal transduction);GO:0004984(olfactory receptor activity);GO:0007608(sensory perception of smell);GO:0050896(response to stimulus);GO:0050911(detection of chemical stimulus involved in sensory perception of smell);GO:0005549(odorant binding)","04740(Olfactory transduction)","K04257","NA","olfactory receptor family 8 subfamily H member 1 [Source:HGNC Symbol;Acc:HGNC:14824]",{"v":0.0140786491646778,"d":"0.01"},{"v":0.0155554899420389,"d":"0.02"},{"v":0.905059835282338,"d":"0.91"},{"v":-0.143914920137364,"d":"-0.14"},1,1,"down","no"]
["ENSG00000147614","ATP6V0D2","ENST00000285393","GO:0015078(hydrogen ion transmembrane transporter activity);GO:0015991(ATP hydrolysis coupled proton transport);GO:0033179(proton-transporting V-type ATPase, V0 domain);GO:0006810(transport);GO:0016020(membrane);GO:0006811(ion transport);GO:0015992(proton transport);GO:0005768(endosome);GO:0005769(early endosome);GO:0016324(apical plasma membrane);GO:0005515(protein binding);GO:0070062(extracellular exosome);GO:0034220(ion transmembrane transport);GO:0010008(endosome membrane);GO:0005765(lysosomal membrane);GO:0030670(phagocytic vesicle membrane);GO:0008286(insulin receptor signaling pathway);GO:0016241(regulation of macroautophagy);GO:0033572(transferrin transport);GO:0090383(phagosome acidification);GO:0008553(hydrogen-exporting ATPase activity, phosphorylative mechanism);GO:0046961(proton-transporting ATPase activity, rotational mechanism);GO:0007034(vacuolar transport);GO:0007035(vacuolar acidification);GO:0016471(vacuolar proton-transporting V-type ATPase complex)","00190(Oxidative phosphorylation);04145(Phagosome);04142(Lysosome);04966(Collecting duct acid secretion);04721(Synaptic vesicle cycle);05203(Viral carcinogenesis);05323(Rheumatoid arthritis);05110(Vibrio cholerae infection);05120(Epithelial cell signaling in Helicobacter pylori infection);05152(Tuberculosis)","K02146","NA","ATPase H+ transporting V0 subunit d2 [Source:HGNC Symbol;Acc:HGNC:18266]",{"v":0.0137715488372093,"d":"0.01"},0,"inf","inf",1,1,"up","no"]
["ENSG00000170703","TTLL6","ENST00000416950;ENST00000490027","GO:0005737(cytoplasm);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0006464(cellular protein modification process);GO:0005856(cytoskeleton);GO:0042995(cell projection);GO:0016874(ligase activity);GO:0005874(microtubule);GO:0005515(protein binding);GO:0005929(cilium);GO:0005829(cytosol);GO:0036064(ciliary basal body);GO:0070740(tubulin-glutamic acid ligase activity);GO:0018095(protein polyglutamylation);GO:0015631(tubulin binding);GO:0070739(protein-glutamic acid ligase activity);GO:0001578(microtubule bundle formation);GO:0003353(positive regulation of cilium movement);GO:0051013(microtubule severing);GO:0051013(microtubule severing)","NA","NA","NA","tubulin tyrosine ligase like 6 [Source:HGNC Symbol;Acc:HGNC:26664]",{"v":0.0235423660977045,"d":"0.02"},{"v":0.0137702397488719,"d":"0.01"},{"v":1.70965549816467,"d":"1.71"},{"v":0.773705646069756,"d":"0.77"},1,1,"up","no"]
["ENSG00000214796","AC098934.1","ENST00000443294;ENST00000430114","NA","NA","NA","NA",null,{"v":0.00889372954699121,"d":"0.01"},{"v":0.0199251247464503,"d":"0.02"},{"v":0.446357534026262,"d":"0.45"},{"v":-1.16372831763959,"d":"-1.16"},1,1,"down","no"]
["MSTRG.15468","RAB28P5","ENST00000427490","NA","NA","NA","NA","RAB28, member RAS oncogene family pseudogene 5 [Source:HGNC Symbol;Acc:HGNC:51547]",0,{"v":0.116104,"d":"0.12"},"-inf","-inf",1,1,"down","no"]
["ENSG00000268696","ZNF723","ENST00000600766","NA","NA","NA","NA","zinc finger protein 723 [Source:HGNC Symbol;Acc:HGNC:32286]",0,{"v":0.037956,"d":"0.04"},"-inf","-inf",1,1,"down","no"]
["MSTRG.2561","AP001266.2","ENST00000534505","NA","NA","NA","NA",null,{"v":0.461223,"d":"0.46"},{"v":0.432555,"d":"0.43"},{"v":1.0662759649062,"d":"1.07"},{"v":0.0925808730655498,"d":"0.09"},1,1,"up","no"]
["ENSG00000270878","AL136038.4","ENST00000603606","NA","NA","NA","NA",null,{"v":0.242947,"d":"0.24"},0,"inf","inf",1,1,"up","no"]
["ENSG00000262412","AL160291.1","ENST00000574842","NA","NA","NA","NA",null,{"v":0.204343,"d":"0.20"},0,"inf","inf",1,1,"up","no"]
["ENSG00000160307","S100B","ENST00000397648;ENST00000367071;ENST00000291700","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0005509(calcium ion binding);GO:0042803(protein homodimerization activity);GO:0005515(protein binding);GO:0048471(perinuclear region of cytoplasm);GO:0005576(extracellular region);GO:0042802(identical protein binding);GO:0005102(receptor binding);GO:0050786(RAGE receptor binding);GO:0007611(learning or memory);GO:0007613(memory);GO:0008284(positive regulation of cell proliferation);GO:0008360(regulation of cell shape);GO:0031643(positive regulation of myelination);GO:0043065(positive regulation of apoptotic process);GO:0048168(regulation of neuronal synaptic plasticity);GO:0048708(astrocyte differentiation);GO:0050806(positive regulation of synaptic transmission);GO:0051384(response to glucocorticoid);GO:0051597(response to methylmercury);GO:0060291(long-term synaptic potentiation);GO:0071456(cellular response to hypoxia);GO:2001015(negative regulation of skeletal muscle cell differentiation);GO:0005615(extracellular space);GO:0043025(neuronal cell body);GO:0048306(calcium-dependent protein binding);GO:0045087(innate immune response);GO:0043123(positive regulation of I-kappaB kinase/NF-kappaB signaling);GO:0001726(ruffle);GO:0007417(central nervous system development);GO:0008283(cell proliferation);GO:0007409(axonogenesis);GO:0044548(S100 protein binding);GO:0048156(tau protein binding);GO:0048156(tau protein binding)","NA","NA","NA","S100 calcium binding protein B [Source:HGNC Symbol;Acc:HGNC:10500]",{"v":0.231687995856354,"d":"0.23"},{"v":0.301008321823204,"d":"0.30"},{"v":0.769706280720156,"d":"0.77"},{"v":-0.37762007529928,"d":"-0.38"},1,1,"down","no"]
["ENSG00000214244","SETP21","ENST00000514799","NA","NA","NA","NA","SET pseudogene 21 [Source:HGNC Symbol;Acc:HGNC:42940]",0,0,1,0,1,1,"no","no"]
["ENSG00000237886","NALT1","ENST00000450304;ENST00000429224","NA","NA","NA","NA","NOTCH1 associated lncRNA in T-cell acute lymphoblastic leukemia 1 [Source:HGNC Symbol;Acc:HGNC:51192]",{"v":0.122170880514706,"d":"0.12"},{"v":0.112242474264706,"d":"0.11"},{"v":1.08845498386453,"d":"1.09"},{"v":0.12228174202464,"d":"0.12"},1,1,"up","no"]
["ENSG00000220758","VN1R10P","ENST00000447106","NA","NA","NA","NA","vomeronasal 1 receptor 10 pseudogene [Source:HGNC Symbol;Acc:HGNC:13550]",{"v":0.057962,"d":"0.06"},{"v":0.052142,"d":"0.05"},{"v":1.11161827317709,"d":"1.11"},{"v":0.152661455380956,"d":"0.15"},1,1,"up","no"]
["ENSG00000271967","AL583856.2","ENST00000606298","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000111981","ULBP1","ENST00000229708","GO:0016020(membrane);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0005783(endoplasmic reticulum);GO:0015629(actin cytoskeleton);GO:0031225(anchored component of membrane);GO:0050776(regulation of immune response);GO:0030101(natural killer cell activation);GO:0046658(anchored component of plasma membrane);GO:0042267(natural killer cell mediated cytotoxicity);GO:0046703(natural killer cell lectin-like receptor binding)","04650(Natural killer cell mediated cytotoxicity)","K07986","NA","UL16 binding protein 1 [Source:HGNC Symbol;Acc:HGNC:14893]",{"v":0.014343,"d":"0.01"},0,"inf","inf",1,1,"up","no"]
["MSTRG.4811","IGHV4-31;IGHV4-34","ENST00000438142;ENST00000390616;MSTRG.4811.2","GO:0016020(membrane);GO:0005886(plasma membrane);GO:0005576(extracellular region);GO:0002376(immune system process);GO:0003823(antigen binding);GO:0002250(adaptive immune response);GO:0034987(immunoglobulin receptor binding);GO:0006910(phagocytosis, recognition);GO:0006911(phagocytosis, engulfment);GO:0006958(complement activation, classical pathway);GO:0042742(defense response to bacterium);GO:0045087(innate immune response);GO:0050853(B cell receptor signaling pathway);GO:0050871(positive regulation of B cell activation);GO:0009897(external side of plasma membrane);GO:0042571(immunoglobulin complex, circulating);GO:0072562(blood microparticle);GO:0006508(proteolysis);GO:0006955(immune response);GO:0004252(serine-type endopeptidase activity);GO:0006898(receptor-mediated endocytosis);GO:0006956(complement activation);GO:0030449(regulation of complement activation);GO:0038095(Fc-epsilon receptor signaling pathway);GO:0038096(Fc-gamma receptor signaling pathway involved in phagocytosis);GO:0050776(regulation of immune response);GO:0050900(leukocyte migration)","NA","NA","NA","immunoglobulin heavy variable 4-31 [Source:HGNC Symbol;Acc:HGNC:5649];immunoglobulin heavy variable 4-34 [Source:HGNC Symbol;Acc:HGNC:5650]",{"v":18.0941576376812,"d":"18.09"},{"v":0.622285173913043,"d":"0.62"},{"v":29.0769544193088,"d":"29.08"},{"v":4.8618042611785,"d":"4.86"},1,1,"up","no"]
["ENSG00000203877","RIPPLY2","ENST00000635617","GO:0005634(nucleus);GO:0005515(protein binding);GO:0007275(multicellular organism development);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0009880(embryonic pattern specification);GO:0001756(somitogenesis);GO:0032525(somite rostral/caudal axis specification);GO:0001503(ossification);GO:0007219(Notch signaling pathway);GO:0007368(determination of left/right symmetry);GO:0009798(axis specification);GO:0010468(regulation of gene expression);GO:0036342(post-anal tail morphogenesis);GO:0060349(bone morphogenesis)","NA","NA","NA","ripply transcriptional repressor 2 [Source:HGNC Symbol;Acc:HGNC:21390]",{"v":0.0122385158197507,"d":"0.01"},0,"inf","inf",1,1,"up","no"]
["ENSG00000110436","SLC1A2","ENST00000278379","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0046872(metal ion binding);GO:0015293(symporter activity);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0005887(integral component of plasma membrane);GO:0006865(amino acid transport);GO:0009986(cell surface);GO:0005314(high-affinity glutamate transmembrane transporter activity);GO:0015171(amino acid transmembrane transporter activity);GO:0006811(ion transport);GO:0014047(glutamate secretion);GO:0007268(chemical synaptic transmission);GO:0070207(protein homotrimerization);GO:0005313(L-glutamate transmembrane transporter activity);GO:0015501(glutamate:sodium symporter activity);GO:0070779(D-aspartate import);GO:0089711(L-glutamate transmembrane transport);GO:0098712(L-glutamate import across plasma membrane);GO:0008509(anion transmembrane transporter activity);GO:0007399(nervous system development);GO:0007632(visual behavior);GO:0009416(response to light stimulus);GO:0009611(response to wounding);GO:0010259(multicellular organism aging);GO:0015813(L-glutamate transport);GO:0021537(telencephalon development);GO:0030534(adult behavior);GO:0031668(cellular response to extracellular stimulus);GO:0035264(multicellular organism growth);GO:0042493(response to drug);GO:0043200(response to amino acid);GO:0046326(positive regulation of glucose import);GO:0098656(anion transmembrane transport);GO:0030424(axon);GO:0030673(axolemma);GO:0055085(transmembrane transport)","04724(Glutamatergic synapse);05014(Amyotrophic lateral sclerosis (ALS))","K05613","NA","solute carrier family 1 member 2 [Source:HGNC Symbol;Acc:HGNC:10940]",0,{"v":0.0101992610493877,"d":"0.01"},"-inf","-inf",1,1,"down","no"]
["ENSG00000218996","ARL4AP5","ENST00000404372","NA","NA","NA","NA","ADP ribosylation factor like GTPase 4A pseudogene 5 [Source:HGNC Symbol;Acc:HGNC:52374]",0,{"v":0.113742,"d":"0.11"},"-inf","-inf",1,1,"down","no"]
["ENSG00000248131","LINC01194","ENST00000505877","NA","NA","NA","NA","long intergenic non-protein coding RNA 1194 [Source:HGNC Symbol;Acc:HGNC:37171]",0,0,1,0,1,1,"no","no"]
["ENSG00000198125","MB","ENST00000397326","GO:0006810(transport);GO:0046872(metal ion binding);GO:0020037(heme binding);GO:0005344(oxygen transporter activity);GO:0019825(oxygen binding);GO:0015671(oxygen transport);GO:0001666(response to hypoxia);GO:0007507(heart development);GO:0009725(response to hormone);GO:0031444(slow-twitch skeletal muscle fiber contraction);GO:0042542(response to hydrogen peroxide);GO:0043353(enucleate erythrocyte differentiation);GO:0050873(brown fat cell differentiation);GO:0005829(cytosol);GO:0070062(extracellular exosome)","NA","NA","NA","myoglobin [Source:HGNC Symbol;Acc:HGNC:6915]",{"v":0.0411728247232472,"d":"0.04"},{"v":0.0244970908671587,"d":"0.02"},{"v":1.6807230273389,"d":"1.68"},{"v":0.749081997026463,"d":"0.75"},1,1,"up","no"]
["ENSG00000177694","NAALADL2","ENST00000414826;ENST00000454872","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005515(protein binding);GO:0005515(protein binding)","NA","NA","NA","N-acetylated alpha-linked acidic dipeptidase like 2 [Source:HGNC Symbol;Acc:HGNC:23219]",{"v":0.020282655606239,"d":"0.02"},0,"inf","inf",1,1,"up","no"]
["ENSG00000262529","AC130650.1","ENST00000570581","NA","NA","NA","NA",null,0,{"v":0.047398,"d":"0.05"},"-inf","-inf",1,1,"down","no"]
["ENSG00000166866","MYO1A","ENST00000300119;ENST00000476795;ENST00000442789","GO:0005737(cytoplasm);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0003774(motor activity);GO:0016459(myosin complex);GO:0003779(actin binding);GO:0005516(calmodulin binding);GO:0031941(filamentous actin);GO:0016323(basolateral plasma membrane);GO:0007605(sensory perception of sound);GO:0005902(microvillus);GO:0005903(brush border);GO:0016328(lateral plasma membrane);GO:0030864(cortical actin cytoskeleton);GO:0051648(vesicle localization);GO:0051015(actin filament binding);GO:0030030(cell projection organization);GO:0030033(microvillus assembly);GO:0009925(basal plasma membrane);GO:0016324(apical plasma membrane);GO:0044853(plasma membrane raft);GO:0044853(plasma membrane raft)","NA","NA","NA","myosin IA [Source:HGNC Symbol;Acc:HGNC:7595]",{"v":0.0779867796304642,"d":"0.08"},{"v":0.175648660657954,"d":"0.18"},{"v":0.443993021855887,"d":"0.44"},{"v":-1.17139109266563,"d":"-1.17"},1,1,"down","no"]
["ENSG00000108878","CACNG1","ENST00000226021","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005244(voltage-gated ion channel activity);GO:0006811(ion transport);GO:0034765(regulation of ion transmembrane transport);GO:0005515(protein binding);GO:0006816(calcium ion transport);GO:0070588(calcium ion transmembrane transport);GO:0005245(voltage-gated calcium channel activity);GO:0005262(calcium channel activity);GO:0005891(voltage-gated calcium channel complex);GO:0005886(plasma membrane);GO:0006936(muscle contraction);GO:0061337(cardiac conduction);GO:0070296(sarcoplasmic reticulum calcium ion transport)","04010(MAPK signaling pathway);04921(Oxytocin signaling pathway);04260(Cardiac muscle contraction);04261(Adrenergic signaling in cardiomyocytes);05410(Hypertrophic cardiomyopathy (HCM));05412(Arrhythmogenic right ventricular cardiomyopathy (ARVC));05414(Dilated cardiomyopathy (DCM))","K04866","NA","calcium voltage-gated channel auxiliary subunit gamma 1 [Source:HGNC Symbol;Acc:HGNC:1405]",{"v":0.038991,"d":"0.04"},{"v":0.060784,"d":"0.06"},{"v":0.64146814951303,"d":"0.64"},{"v":-0.640550461186375,"d":"-0.64"},1,1,"down","no"]
["ENSG00000232268","OR52I1","ENST00000530443","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0004930(G-protein coupled receptor activity);GO:0007186(G-protein coupled receptor signaling pathway);GO:0005886(plasma membrane);GO:0004871(signal transducer activity);GO:0007165(signal transduction);GO:0004984(olfactory receptor activity);GO:0007608(sensory perception of smell);GO:0050896(response to stimulus);GO:0050911(detection of chemical stimulus involved in sensory perception of smell)","04740(Olfactory transduction)","K04257","NA","olfactory receptor family 52 subfamily I member 1 [Source:HGNC Symbol;Acc:HGNC:15220]",{"v":0.01736,"d":"0.02"},0,"inf","inf",1,1,"up","no"]
["MSTRG.8149","HIPK4","ENST00000291823","GO:0005737(cytoplasm);GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0016572(histone phosphorylation);GO:0018105(peptidyl-serine phosphorylation);GO:0046777(protein autophosphorylation);GO:1901796(regulation of signal transduction by p53 class mediator);GO:0005634(nucleus)","04218(Cellular senescence)","K08826","EC:2.7.11.1","homeodomain interacting protein kinase 4 [Source:HGNC Symbol;Acc:HGNC:19007]",{"v":0.035841,"d":"0.04"},{"v":0.072179,"d":"0.07"},{"v":0.496557170368113,"d":"0.50"},{"v":-1.00996826503239,"d":"-1.01"},1,1,"down","no"]
["ENSG00000218153","KRT18P22","ENST00000402024","NA","NA","NA","NA","keratin 18 pseudogene 22 [Source:HGNC Symbol;Acc:HGNC:33390]",0,0,1,0,1,1,"no","no"]
["ENSG00000241416","KRT8P13","ENST00000463294","NA","NA","NA","NA","keratin 8 pseudogene 13 [Source:HGNC Symbol;Acc:HGNC:33365]",{"v":0.046482,"d":"0.05"},0,"inf","inf",1,1,"up","no"]
["ENSG00000183833","MAATS1","ENST00000273390","GO:0005737(cytoplasm);GO:0031514(motile cilium);GO:0005739(mitochondrion);GO:0005856(cytoskeleton);GO:0042995(cell projection);GO:0005515(protein binding);GO:0003341(cilium movement);GO:0005930(axoneme);GO:0001536(radial spoke stalk);GO:0016020(membrane);GO:0016021(integral component of membrane)","NA","NA","NA","MYCBP associated and testis expressed 1 [Source:HGNC Symbol;Acc:HGNC:24010]",{"v":0.00634257120743034,"d":"0.01"},{"v":0.00565385294117647,"d":"0.01"},{"v":1.12181396888448,"d":"1.12"},{"v":0.165833452756054,"d":"0.17"},1,1,"up","no"]
["MSTRG.5910","AC007608.3","ENST00000570167;ENST00000570241","NA","NA","NA","NA",null,{"v":0.282789762464455,"d":"0.28"},{"v":0.0754483097630332,"d":"0.08"},{"v":3.74812588052186,"d":"3.75"},{"v":1.90616940661369,"d":"1.91"},1,1,"up","no"]
["ENSG00000187980","PLA2G2C","ENST00000429261","GO:0046872(metal ion binding);GO:0005509(calcium ion binding);GO:0005576(extracellular region);GO:0006644(phospholipid metabolic process);GO:0016042(lipid catabolic process);GO:0050482(arachidonic acid secretion);GO:0016787(hydrolase activity);GO:0006629(lipid metabolic process);GO:0004623(phospholipase A2 activity)","00564(Glycerophospholipid metabolism);00565(Ether lipid metabolism);00590(Arachidonic acid metabolism);00591(Linoleic acid metabolism);00592(alpha-Linolenic acid metabolism);04014(Ras signaling pathway);04270(Vascular smooth muscle contraction);04972(Pancreatic secretion);04975(Fat digestion and absorption)","K01047","EC:3.1.1.4","phospholipase A2 group IIC [Source:HGNC Symbol;Acc:HGNC:9032]",{"v":0.0155859396604002,"d":"0.02"},0,"inf","inf",1,1,"up","no"]
["ENSG00000146352","CLVS2","ENST00000275162","GO:0016020(membrane);GO:0006810(transport);GO:0005215(transporter activity);GO:0005794(Golgi apparatus);GO:0005622(intracellular);GO:0005802(trans-Golgi network);GO:0031410(cytoplasmic vesicle);GO:0030136(clathrin-coated vesicle);GO:0080025(phosphatidylinositol-3,5-bisphosphate binding);GO:0008289(lipid binding);GO:0005768(endosome);GO:0007040(lysosome organization);GO:0031901(early endosome membrane);GO:0032588(trans-Golgi network membrane);GO:0030669(clathrin-coated endocytic vesicle membrane)","NA","NA","NA","clavesin 2 [Source:HGNC Symbol;Acc:HGNC:23046]",0,{"v":0.003972,"d":"0.00"},"-inf","-inf",1,1,"down","no"]
["MSTRG.7687","STAP2","ENST00000601179;ENST00000600324;ENST00000599736","GO:0005737(cytoplasm);GO:0005515(protein binding);GO:0005886(plasma membrane);GO:0005829(cytosol);GO:0042531(positive regulation of tyrosine phosphorylation of STAT protein);GO:0042531(positive regulation of tyrosine phosphorylation of STAT protein)","NA","NA","NA","signal transducing adaptor family member 2 [Source:HGNC Symbol;Acc:HGNC:30430]",{"v":0.152319207519884,"d":"0.15"},{"v":0.0409954967462039,"d":"0.04"},{"v":3.71551071725917,"d":"3.72"},{"v":1.89356053071422,"d":"1.89"},1,1,"up","no"]
["MSTRG.15365","TSIX","ENST00000604411","NA","NA","NA","NA","TSIX transcript, XIST antisense RNA [Source:HGNC Symbol;Acc:HGNC:12377]",{"v":0.001388,"d":"0.00"},0,"inf","inf",1,1,"up","no"]
["MSTRG.5510","AL133297.1","ENST00000568149","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000236751","LINC01186","ENST00000446884","NA","NA","NA","NA","long intergenic non-protein coding RNA 1186 [Source:HGNC Symbol;Acc:HGNC:49573]",0,{"v":0.092329,"d":"0.09"},"-inf","-inf",1,1,"down","no"]
["ENSG00000116885","OSCP1","ENST00000528112;ENST00000356637;ENST00000468441;ENST00000525869","GO:0006810(transport);GO:0016020(membrane);GO:0005886(plasma membrane);GO:0009925(basal plasma membrane);GO:1903955(positive regulation of protein targeting to mitochondrion);GO:1903955(positive regulation of protein targeting to mitochondrion)","NA","NA","NA","organic solute carrier partner 1 [Source:HGNC Symbol;Acc:HGNC:29971]",{"v":0.00191375932568149,"d":"0.00"},{"v":0.114100356527977,"d":"0.11"},{"v":0.0167725972461115,"d":"0.02"},{"v":-5.89775008143568,"d":"-5.90"},1,1,"down","no"]
["MSTRG.3102","AC124891.1","ENST00000536322","NA","NA","NA","NA",null,0,{"v":0.087907,"d":"0.09"},"-inf","-inf",1,1,"down","no"]
["ENSG00000102024","PLS3","ENST00000489283;ENST00000466150;ENST00000420625;ENST00000355899;ENST00000289290","GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0005509(calcium ion binding);GO:0003779(actin binding);GO:0060348(bone development);GO:0051015(actin filament binding);GO:0051017(actin filament bundle assembly);GO:0051639(actin filament network formation);GO:0005884(actin filament);GO:0051764(actin crosslink formation);GO:0032432(actin filament bundle);GO:0032432(actin filament bundle)","NA","NA","NA","plastin 3 [Source:HGNC Symbol;Acc:HGNC:9091]",{"v":0.0946989717004147,"d":"0.09"},{"v":0.115219302268846,"d":"0.12"},{"v":0.821901971593697,"d":"0.82"},{"v":-0.282961761234909,"d":"-0.28"},1,1,"down","no"]
["MSTRG.6819","C17orf113","ENST00000587304","NA","NA","NA","NA","chromosome 17 open reading frame 113 [Source:HGNC Symbol;Acc:HGNC:53437]",0,{"v":0.048712,"d":"0.05"},"-inf","-inf",1,1,"down","no"]
["MSTRG.15488","U52111.1","ENST00000434284","NA","NA","NA","NA",null,{"v":0.0135561251149954,"d":"0.01"},{"v":0.0205662612695492,"d":"0.02"},{"v":0.659143873420827,"d":"0.66"},{"v":-0.60133469366601,"d":"-0.60"},1,1,"down","no"]
["ENSG00000226306","NPY6R","ENST00000503807","NA","NA","NA","NA","neuropeptide Y receptor Y6 (pseudogene) [Source:HGNC Symbol;Acc:HGNC:7959]",{"v":0.0172601900937082,"d":"0.02"},{"v":0.0152691593038822,"d":"0.02"},{"v":1.13039557386239,"d":"1.13"},{"v":0.176827721829006,"d":"0.18"},1,1,"up","no"]
["MSTRG.14059","TRBV4-2","ENST00000390392","NA","NA","NA","NA","T-cell receptor beta variable 4-2 [Source:HGNC Symbol;Acc:HGNC:12216]",{"v":3.560485,"d":"3.56"},{"v":0.815213,"d":"0.82"},{"v":4.36755179321233,"d":"4.37"},{"v":2.12682481164061,"d":"2.13"},1,1,"up","no"]
["ENSG00000265185","SNORD3B-1","ENST00000577988","NA","03013(RNA transport);03008(Ribosome biogenesis in eukaryotes)","NA","NA","small nucleolar RNA, C/D box 3B-1 [Source:HGNC Symbol;Acc:HGNC:10168]",0,{"v":0.06019,"d":"0.06"},"-inf","-inf",1,1,"down","no"]
["ENSG00000251419","AC108120.3","ENST00000505953","NA","NA","NA","NA",null,0,{"v":0.030214,"d":"0.03"},"-inf","-inf",1,1,"down","no"]
["MSTRG.5306","TYRO3P","ENST00000558165","NA","NA","NA","NA","TYRO3P protein tyrosine kinase pseudogene [Source:HGNC Symbol;Acc:HGNC:12447]",{"v":0.018116,"d":"0.02"},0,"inf","inf",1,1,"up","no"]
["MSTRG.12134","HMGN2P4","ENST00000506772","NA","NA","NA","NA","high mobility group nucleosomal binding domain 2 pseudogene 4 [Source:HGNC Symbol;Acc:HGNC:33567]",0,{"v":0.119748,"d":"0.12"},"-inf","-inf",1,1,"down","no"]
["ENSG00000233039","MTND5P30","ENST00000452896","NA","NA","NA","NA","mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 5 pseudogene 30 [Source:HGNC Symbol;Acc:HGNC:42292]",{"v":0.012373,"d":"0.01"},0,"inf","inf",1,1,"up","no"]
["ENSG00000197696","NMB","ENST00000360476;ENST00000394588","GO:0005515(protein binding);GO:0005576(extracellular region);GO:0007218(neuropeptide signaling pathway);GO:0007165(signal transduction);GO:0007267(cell-cell signaling);GO:0005179(hormone activity);GO:0031710(neuromedin B receptor binding);GO:0007204(positive regulation of cytosolic calcium ion concentration);GO:0008284(positive regulation of cell proliferation);GO:0042593(glucose homeostasis);GO:0046887(positive regulation of hormone secretion);GO:0046888(negative regulation of hormone secretion);GO:0050482(arachidonic acid secretion);GO:0043005(neuron projection);GO:0043005(neuron projection)","04080(Neuroactive ligand-receptor interaction);04080(Neuroactive ligand-receptor interaction)","K05223","NA","neuromedin B [Source:HGNC Symbol;Acc:HGNC:7842]",{"v":0.930132004892368,"d":"0.93"},{"v":0.0892830636007828,"d":"0.09"},{"v":10.4177877346518,"d":"10.42"},{"v":3.38097704207181,"d":"3.38"},1,1,"up","no"]
["ENSG00000175697","GPR156","ENST00000464295","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0004930(G-protein coupled receptor activity);GO:0007186(G-protein coupled receptor signaling pathway);GO:0005886(plasma membrane);GO:0004871(signal transducer activity);GO:0007165(signal transduction);GO:0004965(G-protein coupled GABA receptor activity)","04080(Neuroactive ligand-receptor interaction)","K04617","NA","G protein-coupled receptor 156 [Source:HGNC Symbol;Acc:HGNC:20844]",0,0,1,0,1,1,"no","no"]
["ENSG00000178538","CA8","ENST00000317995;ENST00000528666;ENST00000529918","GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0006730(one-carbon metabolic process);GO:0005515(protein binding);GO:0004089(carbonate dehydratase activity);GO:0048015(phosphatidylinositol-mediated signaling);GO:0005737(cytoplasm);GO:0005737(cytoplasm)","00910(Nitrogen metabolism);00910(Nitrogen metabolism)","K01672","EC:4.2.1.1","carbonic anhydrase 8 [Source:HGNC Symbol;Acc:HGNC:1382]",{"v":0.0811152467577382,"d":"0.08"},{"v":0.0994334757046516,"d":"0.10"},{"v":0.815774025627705,"d":"0.82"},{"v":-0.293758522660909,"d":"-0.29"},1,1,"down","no"]
["MSTRG.11652","ENAM","ENST00000472597;ENST00000472903;ENST00000396073;ENST00000509221","GO:0005515(protein binding);GO:0005576(extracellular region);GO:0005578(proteinaceous extracellular matrix);GO:0031214(biomineral tissue development);GO:0044267(cellular protein metabolic process);GO:0043687(post-translational protein modification);GO:0005788(endoplasmic reticulum lumen);GO:0030345(structural constituent of tooth enamel);GO:0022604(regulation of cell morphogenesis);GO:0036305(ameloblast differentiation);GO:0042475(odontogenesis of dentin-containing tooth);GO:0070175(positive regulation of enamel mineralization);GO:0097186(amelogenesis);GO:0097186(amelogenesis)","NA","NA","NA","enamelin [Source:HGNC Symbol;Acc:HGNC:3344]",{"v":0.0626792486967188,"d":"0.06"},{"v":0.0153987606562404,"d":"0.02"},{"v":4.07040865794078,"d":"4.07"},{"v":2.02517364441488,"d":"2.03"},1,1,"up","no"]
["MSTRG.2942","CLMP","ENST00000448775;ENST00000529128","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005886(plasma membrane);GO:0030054(cell junction);GO:0005923(bicellular tight junction);GO:0070062(extracellular exosome);GO:0009986(cell surface);GO:0005881(cytoplasmic microtubule);GO:0048565(digestive tract development);GO:0048565(digestive tract development)","NA","NA","NA","CXADR like membrane protein [Source:HGNC Symbol;Acc:HGNC:24039]",{"v":0.0577025309005297,"d":"0.06"},{"v":0.0350512317049245,"d":"0.04"},{"v":1.64623404353642,"d":"1.65"},{"v":0.71916945692981,"d":"0.72"},1,1,"up","no"]
["ENSG00000118523","CTGF","ENST00000367976","GO:0070374(positive regulation of ERK1 and ERK2 cascade);GO:0005794(Golgi apparatus);GO:0043231(intracellular membrane-bounded organelle);GO:0007155(cell adhesion);GO:0005576(extracellular region);GO:0005515(protein binding);GO:0005520(insulin-like growth factor binding);GO:0001558(regulation of cell growth);GO:0005578(proteinaceous extracellular matrix);GO:0008201(heparin binding);GO:0007267(cell-cell signaling);GO:0008022(protein C-terminus binding);GO:0071897(DNA biosynthetic process);GO:0005886(plasma membrane);GO:0009611(response to wounding);GO:0006367(transcription initiation from RNA polymerase II promoter);GO:0046330(positive regulation of JNK cascade);GO:0005178(integrin binding);GO:0060548(negative regulation of cell death);GO:0051496(positive regulation of stress fiber assembly);GO:0008544(epidermis development);GO:0019216(regulation of lipid metabolic process);GO:0045597(positive regulation of cell differentiation);GO:0001968(fibronectin binding);GO:0008083(growth factor activity);GO:0001502(cartilage condensation);GO:0001503(ossification);GO:0001525(angiogenesis);GO:0001894(tissue homeostasis);GO:0001934(positive regulation of protein phosphorylation);GO:0007160(cell-matrix adhesion);GO:0007229(integrin-mediated signaling pathway);GO:0007568(aging);GO:0008284(positive regulation of cell proliferation);GO:0008543(fibroblast growth factor receptor signaling pathway);GO:0009749(response to glucose);GO:0010628(positive regulation of gene expression);GO:0010629(negative regulation of gene expression);GO:0010942(positive regulation of cell death);GO:0014070(response to organic cyclic compound);GO:0016477(cell migration);GO:0030154(cell differentiation);GO:0030324(lung development);GO:0032330(regulation of chondrocyte differentiation);GO:0032355(response to estradiol);GO:0032967(positive regulation of collagen biosynthetic process);GO:0034059(response to anoxia);GO:0035556(intracellular signal transduction);GO:0035988(chondrocyte proliferation);GO:0043200(response to amino acid);GO:0043280(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process);GO:0043434(response to peptide hormone);GO:0050867(positive regulation of cell activation);GO:0051385(response to mineralocorticoid);GO:0060401(cytosolic calcium ion transport);GO:0060452(positive regulation of cardiac muscle contraction);GO:0061448(connective tissue development);GO:0070278(extracellular matrix constituent secretion);GO:0070318(positive regulation of G0 to G1 transition);GO:0070542(response to fatty acid);GO:0072593(reactive oxygen species metabolic process);GO:0005615(extracellular space);GO:0005801(cis-Golgi network);GO:0005829(cytosol);GO:0005938(cell cortex);GO:0048471(perinuclear region of cytoplasm)","04390(Hippo signaling pathway);04371(Apelin signaling pathway)","K06827","NA","connective tissue growth factor [Source:HGNC Symbol;Acc:HGNC:2500]",{"v":0.035971,"d":"0.04"},{"v":0.067778,"d":"0.07"},{"v":0.530717932072354,"d":"0.53"},{"v":-0.913982799058897,"d":"-0.91"},1,1,"down","no"]
["ENSG00000242142","SERBP1P3","ENST00000459980","NA","NA","NA","NA","SERPINE1 mRNA binding protein 1 pseudogene 3 [Source:HGNC Symbol;Acc:HGNC:44630]",0,0,1,0,1,1,"no","no"]
["MSTRG.1285","AL358473.1","ENST00000458003;ENST00000446333","NA","NA","NA","NA",null,{"v":0.161083083238312,"d":"0.16"},{"v":0.00112678192702395,"d":"0.00"},{"v":142.958525846934,"d":"142.96"},{"v":7.15945285262797,"d":"7.16"},1,1,"up","no"]
["MSTRG.8271","NOP53-AS1","ENST00000602048","NA","NA","NA","NA","NOP53 antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:51587]",{"v":0.078634,"d":"0.08"},{"v":0.04608,"d":"0.05"},{"v":1.70646701388889,"d":"1.71"},{"v":0.771012527323468,"d":"0.77"},1,1,"up","no"]
["ENSG00000178997","EXD1","ENST00000314992","GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0005737(cytoplasm);GO:0006139(nucleobase-containing compound metabolic process);GO:0042803(protein homodimerization activity);GO:0005515(protein binding);GO:0051321(meiotic cell cycle);GO:0031047(gene silencing by RNA);GO:0034587(piRNA metabolic process);GO:1990923(PET complex);GO:0043186(P granule)","NA","NA","NA","exonuclease 3'-5' domain containing 1 [Source:HGNC Symbol;Acc:HGNC:28507]",{"v":0.0126559841573341,"d":"0.01"},0,"inf","inf",1,1,"up","no"]
["ENSG00000224844","AC107079.1","ENST00000416509","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000260812","RARRES2P7","ENST00000567349","NA","NA","NA","NA","retinoic acid receptor responder 2 pseudogene 7 [Source:HGNC Symbol;Acc:HGNC:48709]",0,{"v":0.097279,"d":"0.10"},"-inf","-inf",1,1,"down","no"]
["MSTRG.4162","TPPP2","ENST00000534434;ENST00000495665","GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0015631(tubulin binding);GO:0015631(tubulin binding)","NA","NA","NA","tubulin polymerization promoting protein family member 2 [Source:HGNC Symbol;Acc:HGNC:19293]",{"v":0.00867352331606218,"d":"0.01"},{"v":0.0417831129533679,"d":"0.04"},{"v":0.207584421145028,"d":"0.21"},{"v":-2.26822991891876,"d":"-2.27"},1,1,"down","no"]
["ENSG00000166482","MFAP4","ENST00000395592","GO:0005615(extracellular space);GO:0007155(cell adhesion);GO:0005576(extracellular region);GO:0005578(proteinaceous extracellular matrix);GO:0005515(protein binding);GO:0003674(molecular_function);GO:0070062(extracellular exosome);GO:0031012(extracellular matrix);GO:0097435(supramolecular fiber organization);GO:0009650(UV protection);GO:0071953(elastic fiber);GO:0001527(microfibril);GO:0010712(regulation of collagen metabolic process);GO:0048251(elastic fiber assembly);GO:0071493(cellular response to UV-B)","NA","NA","NA","microfibril associated protein 4 [Source:HGNC Symbol;Acc:HGNC:7035]",{"v":0.0538670687732342,"d":"0.05"},{"v":0.0504905576208178,"d":"0.05"},{"v":1.06687411095306,"d":"1.07"},{"v":0.0933899510276853,"d":"0.09"},1,1,"up","no"]
["MSTRG.2755","KCTD21-AS1","ENST00000600795;ENST00000527321;ENST00000500113;ENST00000532831","NA","NA","NA","NA","KCTD21 antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:48674]",{"v":0.0751887824175824,"d":"0.08"},{"v":0.0848597968253968,"d":"0.08"},{"v":0.886035381068458,"d":"0.89"},{"v":-0.174563785415366,"d":"-0.17"},1,1,"down","no"]
["MSTRG.11775","AC018797.2","ENST00000501133","NA","NA","NA","NA",null,{"v":0.434463,"d":"0.43"},{"v":0.60539,"d":"0.61"},{"v":0.717658038619733,"d":"0.72"},{"v":-0.478631525919237,"d":"-0.48"},1,1,"down","no"]
["ENSG00000102468","HTR2A","ENST00000542664;ENST00000612998;ENST00000378688","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0004930(G-protein coupled receptor activity);GO:0007186(G-protein coupled receptor signaling pathway);GO:0005887(integral component of plasma membrane);GO:0005886(plasma membrane);GO:0042995(cell projection);GO:0004871(signal transducer activity);GO:0007165(signal transduction);GO:0005901(caveola);GO:0031410(cytoplasmic vesicle);GO:0030425(dendrite);GO:0004993(G-protein coupled serotonin receptor activity);GO:0006939(smooth muscle contraction);GO:0046883(regulation of hormone secretion);GO:0050795(regulation of behavior);GO:0043198(dendritic shaft);GO:0046718(viral entry into host cell);GO:0030424(axon);GO:0016032(viral process);GO:0070374(positive regulation of ERK1 and ERK2 cascade);GO:0014065(phosphatidylinositol 3-kinase signaling);GO:0008144(drug binding);GO:0007268(chemical synaptic transmission);GO:0001618(virus receptor activity);GO:0007200(phospholipase C-activating G-protein coupled receptor signaling pathway);GO:0030594(neurotransmitter receptor activity);GO:0006874(cellular calcium ion homeostasis);GO:0042493(response to drug);GO:0051209(release of sequestered calcium ion into cytosol);GO:0007202(activation of phospholipase C activity);GO:0007210(serotonin receptor signaling pathway);GO:0007610(behavior);GO:0010513(positive regulation of phosphatidylinositol biosynthetic process);GO:0051378(serotonin binding);GO:0071886(1-(4-iodo-2,5-dimethoxyphenyl)propan-2-amine binding);GO:0098664(G-protein coupled serotonin receptor signaling pathway);GO:0001965(G-protein alpha-subunit binding);GO:0032403(protein complex binding);GO:0001659(temperature homeostasis);GO:0007204(positive regulation of cytosolic calcium ion concentration);GO:0007208(phospholipase C-activating serotonin receptor signaling pathway);GO:0007568(aging);GO:0007613(memory);GO:0008219(cell death);GO:0008284(positive regulation of cell proliferation);GO:0014059(regulation of dopamine secretion);GO:0014824(artery smooth muscle contraction);GO:0014832(urinary bladder smooth muscle contraction);GO:0019233(sensory perception of pain);GO:0030431(sleep);GO:0033674(positive regulation of kinase activity);GO:0043267(negative regulation of potassium ion transport);GO:0043406(positive regulation of MAP kinase activity);GO:0044380(protein localization to cytoskeleton);GO:0045600(positive regulation of fat cell differentiation);GO:0045821(positive regulation of glycolytic process);GO:0045907(positive regulation of vasoconstriction);GO:0048148(behavioral response to cocaine);GO:0050731(positive regulation of peptidyl-tyrosine phosphorylation);GO:0050965(detection of temperature stimulus involved in sensory perception of pain);GO:0050966(detection of mechanical stimulus involved in sensory perception of pain);GO:0051967(negative regulation of synaptic transmission, glutamatergic);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0043025(neuronal cell body);GO:0070852(cell body fiber);GO:0070852(cell body fiber)","04020(Calcium signaling pathway);04080(Neuroactive ligand-receptor interaction);04540(Gap junction);04726(Serotonergic synapse);04750(Inflammatory mediator regulation of TRP channels);04750(Inflammatory mediator regulation of TRP channels)","K04157","NA","5-hydroxytryptamine receptor 2A [Source:HGNC Symbol;Acc:HGNC:5293]",{"v":0.018218637802276,"d":"0.02"},{"v":0.00466349555476529,"d":"0.00"},{"v":3.90664847608993,"d":"3.91"},{"v":1.96593144630283,"d":"1.97"},1,1,"up","no"]
["MSTRG.6640","AC104984.2","ENST00000582938","NA","NA","NA","NA",null,0,{"v":0.11191,"d":"0.11"},"-inf","-inf",1,1,"down","no"]
["ENSG00000187950","OVCH1","ENST00000318184","GO:0046872(metal ion binding);GO:0016787(hydrolase activity);GO:0008233(peptidase activity);GO:0006508(proteolysis);GO:0005576(extracellular region);GO:0004252(serine-type endopeptidase activity);GO:0008236(serine-type peptidase activity)","NA","NA","NA","ovochymase 1 [Source:HGNC Symbol;Acc:HGNC:23080]",{"v":0.0254282440626579,"d":"0.03"},{"v":0.00931342344618494,"d":"0.01"},{"v":2.73027895806392,"d":"2.73"},{"v":1.44904836171476,"d":"1.45"},1,1,"up","no"]
["ENSG00000233471","KRT18P62","ENST00000446618","NA","NA","NA","NA","keratin 18 pseudogene 62 [Source:HGNC Symbol;Acc:HGNC:48889]",{"v":0.039939,"d":"0.04"},0,"inf","inf",1,1,"up","no"]
["ENSG00000188760","TMEM198","ENST00000373883;ENST00000344458","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005886(plasma membrane);GO:0007275(multicellular organism development);GO:0016055(Wnt signaling pathway);GO:0031410(cytoplasmic vesicle);GO:0090263(positive regulation of canonical Wnt signaling pathway);GO:0090263(positive regulation of canonical Wnt signaling pathway)","NA","NA","NA","transmembrane protein 198 [Source:HGNC Symbol;Acc:HGNC:33704]",{"v":0.0199385725368503,"d":"0.02"},{"v":0.0268044181536074,"d":"0.03"},{"v":0.743853958052319,"d":"0.74"},{"v":-0.426908692203598,"d":"-0.43"},1,1,"down","no"]
["ENSG00000157502","MUM1L1","ENST00000337685","GO:0070062(extracellular exosome)","NA","NA","NA","MUM1 like 1 [Source:HGNC Symbol;Acc:HGNC:26583]",{"v":0.0118358406631361,"d":"0.01"},{"v":0.00987477319825006,"d":"0.01"},{"v":1.19859367152185,"d":"1.20"},{"v":0.261342661727349,"d":"0.26"},1,1,"up","no"]
["ENSG00000160339","FCN2","ENST00000291744","GO:0046872(metal ion binding);GO:0030246(carbohydrate binding);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0005581(collagen trimer);GO:0006508(proteolysis);GO:0002376(immune system process);GO:0045087(innate immune response);GO:0003823(antigen binding);GO:0004252(serine-type endopeptidase activity);GO:0006956(complement activation);GO:0070062(extracellular exosome);GO:0050829(defense response to Gram-negative bacterium);GO:0072562(blood microparticle);GO:0048306(calcium-dependent protein binding);GO:0050830(defense response to Gram-positive bacterium);GO:0001867(complement activation, lectin pathway);GO:0043654(recognition of apoptotic cell);GO:0043394(proteoglycan binding);GO:2001065(mannan binding);GO:0008228(opsonization)","NA","NA","NA","ficolin 2 [Source:HGNC Symbol;Acc:HGNC:3624]",{"v":0.061645,"d":"0.06"},{"v":0.159122,"d":"0.16"},{"v":0.387407146717613,"d":"0.39"},{"v":-1.36807752649355,"d":"-1.37"},1,1,"down","no"]
["MSTRG.6533","AC069366.1","ENST00000583159","NA","NA","NA","NA",null,{"v":0.061134,"d":"0.06"},0,"inf","inf",1,1,"up","no"]
["ENSG00000177294","FBXO39","ENST00000321535","GO:0019005(SCF ubiquitin ligase complex);GO:0031146(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)","NA","NA","NA","F-box protein 39 [Source:HGNC Symbol;Acc:HGNC:28565]",{"v":0.0701977947224126,"d":"0.07"},{"v":0.0412250047978067,"d":"0.04"},{"v":1.70279652038142,"d":"1.70"},{"v":0.767906047127021,"d":"0.77"},1,1,"up","no"]
["MSTRG.9237","AC078883.2","ENST00000441212","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000169059","VCX3A","ENST00000381089","GO:0005634(nucleus);GO:0005730(nucleolus);GO:0007420(brain development)","NA","NA","NA","variable charge, X-linked 3A [Source:HGNC Symbol;Acc:HGNC:18159]",0,{"v":0.038211,"d":"0.04"},"-inf","-inf",1,1,"down","no"]
["MSTRG.10877","AC098613.1","ENST00000451485","NA","NA","NA","NA",null,{"v":0.324345,"d":"0.32"},{"v":1.180195,"d":"1.18"},{"v":0.274823228364804,"d":"0.27"},{"v":-1.86342414738907,"d":"-1.86"},1,1,"down","no"]
["MSTRG.3483","NDUFA4L2","ENST00000555173;ENST00000556732;ENST00000556234","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:1902600(hydrogen ion transmembrane transport);GO:0005751(mitochondrial respiratory chain complex IV);GO:0004129(cytochrome-c oxidase activity);GO:0004129(cytochrome-c oxidase activity)","00190(Oxidative phosphorylation);04723(Retrograde endocannabinoid signaling);05010(Alzheimer's disease);05012(Parkinson's disease);05016(Huntington's disease);04932(Non-alcoholic fatty liver disease (NAFLD));04932(Non-alcoholic fatty liver disease (NAFLD))","NA","NA","NDUFA4, mitochondrial complex associated like 2 [Source:HGNC Symbol;Acc:HGNC:29836]",{"v":0.0989481742694227,"d":"0.10"},{"v":0.0281725395580898,"d":"0.03"},{"v":3.51222061700893,"d":"3.51"},{"v":1.81238346932321,"d":"1.81"},1,1,"up","no"]
["ENSG00000283680","AC135068.12","ENST00000637370","NA","NA","NA","NA",null,{"v":0.027606,"d":"0.03"},{"v":0.024503,"d":"0.02"},{"v":1.12663755458515,"d":"1.13"},{"v":0.17202346732631,"d":"0.17"},1,1,"up","no"]
["ENSG00000204335","SP5","ENST00000375281","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0000981(RNA polymerase II transcription factor activity, sequence-specific DNA binding);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0000977(RNA polymerase II regulatory region sequence-specific DNA binding);GO:0043565(sequence-specific DNA binding);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0036342(post-anal tail morphogenesis);GO:0060349(bone morphogenesis);GO:0071407(cellular response to organic cyclic compound)","NA","NA","NA","Sp5 transcription factor [Source:HGNC Symbol;Acc:HGNC:14529]",{"v":0.0249526077669903,"d":"0.02"},{"v":0.0376657660194175,"d":"0.04"},{"v":0.662474453702248,"d":"0.66"},{"v":-0.594063272365946,"d":"-0.59"},1,1,"down","no"]
["ENSG00000223658","C1GALT1C1L","ENST00000475092","GO:0016020(membrane);GO:0016021(integral component of membrane)","NA","NA","NA","C1GALT1-specific chaperone 1 like [Source:HGNC Symbol;Acc:HGNC:51617]",0,{"v":0.038928,"d":"0.04"},"-inf","-inf",1,1,"down","no"]
["ENSG00000267026","AL136084.2","ENST00000589257;ENST00000630758","NA","NA","NA","NA",null,0,{"v":2.15012452909167E-3,"d":"0.00"},"-inf","-inf",1,1,"down","no"]
["ENSG00000197353","LYPD2","ENST00000359228","GO:0016020(membrane);GO:0005886(plasma membrane);GO:0031225(anchored component of membrane);GO:0005576(extracellular region);GO:0070062(extracellular exosome);GO:0006501(C-terminal protein lipidation);GO:0001775(cell activation)","NA","NA","NA","LY6/PLAUR domain containing 2 [Source:HGNC Symbol;Acc:HGNC:25215]",{"v":0.220286,"d":"0.22"},{"v":0.329973,"d":"0.33"},{"v":0.667587954165947,"d":"0.67"},{"v":-0.582970171675523,"d":"-0.58"},1,1,"down","no"]
["ENSG00000258278","CLUHP8","ENST00000547527","NA","NA","NA","NA","clustered mitochondria homolog pseudogene 8 [Source:HGNC Symbol;Acc:HGNC:51573]",{"v":0.024922,"d":"0.02"},0,"inf","inf",1,1,"up","no"]
["ENSG00000227256","MIS18A-AS1","ENST00000453549","NA","NA","NA","NA","MIS18A antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:40106]",{"v":0.045281,"d":"0.05"},0,"inf","inf",1,1,"up","no"]
["MSTRG.481","AL512353.1","ENST00000414798;ENST00000425076","NA","NA","NA","NA",null,0,{"v":0.0729724291898578,"d":"0.07"},"-inf","-inf",1,1,"down","no"]
["ENSG00000118004","COLEC11","ENST00000419002;ENST00000403096;ENST00000418971","GO:0030246(carbohydrate binding);GO:0005576(extracellular region);GO:0005581(collagen trimer);GO:0006508(proteolysis);GO:0007275(multicellular organism development);GO:0004252(serine-type endopeptidase activity);GO:0006898(receptor-mediated endocytosis);GO:0006956(complement activation);GO:0001867(complement activation, lectin pathway);GO:0005537(mannose binding);GO:0032502(developmental process);GO:0032502(developmental process)","04145(Phagosome);04145(Phagosome)","K10066","NA","collectin subfamily member 11 [Source:HGNC Symbol;Acc:HGNC:17213]",{"v":0.0185029665226782,"d":"0.02"},{"v":0.0330561663066955,"d":"0.03"},{"v":0.559743266990112,"d":"0.56"},{"v":-0.837162825518105,"d":"-0.84"},1,1,"down","no"]
["MSTRG.13175","AL022067.1","ENST00000602426","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000254858","MPV17L2","ENST00000599612;ENST00000533807;ENST00000534421","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005743(mitochondrial inner membrane);GO:0005739(mitochondrion);GO:0005762(mitochondrial large ribosomal subunit);GO:0070131(positive regulation of mitochondrial translation);GO:0061668(mitochondrial ribosome assembly);GO:0061668(mitochondrial ribosome assembly)","04146(Peroxisome);04146(Peroxisome)","K13348","NA","MPV17 mitochondrial inner membrane protein like 2 [Source:HGNC Symbol;Acc:HGNC:28177]",{"v":1.51958955784543,"d":"1.52"},{"v":1.55351987915691,"d":"1.55"},{"v":0.978159068469794,"d":"0.98"},{"v":-0.0318589992069065,"d":"-0.03"},1,1,"down","no"]
["ENSG00000272077","AC124045.1","ENST00000606008","NA","NA","NA","NA",null,0,{"v":0.038935,"d":"0.04"},"-inf","-inf",1,1,"down","no"]
["MSTRG.10945","U73169.1","ENST00000395152","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000188101","ALOX15P2","ENST00000340858","NA","NA","NA","NA","arachidonate 15-lipoxygenase pseudogene 2 [Source:HGNC Symbol;Acc:HGNC:39027]",0,{"v":0.014085,"d":"0.01"},"-inf","-inf",1,1,"down","no"]
["ENSG00000081800","SLC13A1","ENST00000439260;ENST00000194130","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005215(transporter activity);GO:0055085(transmembrane transport);GO:0015293(symporter activity);GO:0006811(ion transport);GO:0006814(sodium ion transport);GO:0035725(sodium ion transmembrane transport);GO:1902358(sulfate transmembrane transport);GO:0005886(plasma membrane);GO:0005887(integral component of plasma membrane);GO:0008271(secondary active sulfate transmembrane transporter activity);GO:0015382(sodium:sulfate symporter activity);GO:0008272(sulfate transport);GO:0008272(sulfate transport)","NA","NA","NA","solute carrier family 13 member 1 [Source:HGNC Symbol;Acc:HGNC:10916]",{"v":0.0106802258210646,"d":"0.01"},{"v":0.00396103284258211,"d":"0.00"},{"v":2.69632347054775,"d":"2.70"},{"v":1.43099358307818,"d":"1.43"},1,1,"up","no"]
["ENSG00000260977","AC016722.3","ENST00000568862","NA","NA","NA","NA",null,{"v":0.077566,"d":"0.08"},{"v":0.018524,"d":"0.02"},{"v":4.18732455193263,"d":"4.19"},{"v":2.06602874308835,"d":"2.07"},1,1,"up","no"]
["MSTRG.11409","AHSG","ENST00000411641","GO:0005615(extracellular space);GO:0005794(Golgi apparatus);GO:0010951(negative regulation of endopeptidase activity);GO:0005576(extracellular region);GO:0004869(cysteine-type endopeptidase inhibitor activity);GO:0070062(extracellular exosome);GO:0044267(cellular protein metabolic process);GO:0001501(skeletal system development);GO:0072562(blood microparticle);GO:0043687(post-translational protein modification);GO:0030500(regulation of bone mineralization);GO:0043312(neutrophil degranulation);GO:0006953(acute-phase response);GO:0002576(platelet degranulation);GO:0034774(secretory granule lumen);GO:0005788(endoplasmic reticulum lumen);GO:0031093(platelet alpha granule lumen);GO:0050766(positive regulation of phagocytosis);GO:0019210(kinase inhibitor activity);GO:0046627(negative regulation of insulin receptor signaling pathway);GO:0050727(regulation of inflammatory response);GO:0004866(endopeptidase inhibitor activity);GO:0001503(ossification);GO:0006907(pinocytosis);GO:0030502(negative regulation of bone mineralization);GO:0042326(negative regulation of phosphorylation);GO:0070168(negative regulation of biomineral tissue development);GO:0031012(extracellular matrix)","NA","NA","NA","alpha 2-HS glycoprotein [Source:HGNC Symbol;Acc:HGNC:349]",{"v":0.0192463867403315,"d":"0.02"},{"v":0.0223113527411815,"d":"0.02"},{"v":0.862627513606883,"d":"0.86"},{"v":-0.213190363151627,"d":"-0.21"},1,1,"down","no"]
["ENSG00000175741","RWDD4P2","ENST00000426392","NA","NA","NA","NA","RWD domain containing 4 pseudogene 2 [Source:HGNC Symbol;Acc:HGNC:23754]",0,{"v":0.319151,"d":"0.32"},"-inf","-inf",1,1,"down","no"]
["MSTRG.5788","AC109460.4","ENST00000561471","NA","NA","NA","NA",null,{"v":0.134773,"d":"0.13"},0,"inf","inf",1,1,"up","no"]
["ENSG00000267060","PTGES3L","ENST00000462157;ENST00000591916;ENST00000464183;ENST00000409446","NA","NA","NA","NA","prostaglandin E synthase 3 like [Source:HGNC Symbol;Acc:HGNC:43943]",{"v":0.134503919467787,"d":"0.13"},{"v":0.0454585283613445,"d":"0.05"},{"v":2.95882696418659,"d":"2.96"},{"v":1.56502532843135,"d":"1.57"},1,1,"up","no"]
["ENSG00000164588","HCN1","ENST00000303230","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0055085(transmembrane transport);GO:0000166(nucleotide binding);GO:0005216(ion channel activity);GO:0006811(ion transport);GO:0005887(integral component of plasma membrane);GO:0005244(voltage-gated ion channel activity);GO:0005249(voltage-gated potassium channel activity);GO:0005267(potassium channel activity);GO:0006813(potassium ion transport);GO:0034765(regulation of ion transmembrane transport);GO:0071805(potassium ion transmembrane transport);GO:0005886(plasma membrane);GO:0006814(sodium ion transport);GO:0030552(cAMP binding);GO:0005272(sodium channel activity);GO:0060078(regulation of postsynaptic membrane potential);GO:0035725(sodium ion transmembrane transport);GO:0051289(protein homotetramerization);GO:0071320(cellular response to cAMP);GO:0005222(intracellular cAMP activated cation channel activity);GO:0005248(voltage-gated sodium channel activity);GO:0022843(voltage-gated cation channel activity);GO:0042802(identical protein binding);GO:0042391(regulation of membrane potential);GO:0045176(apical protein localization);GO:0046549(retinal cone cell development);GO:0030424(axon);GO:0030425(dendrite);GO:0098855(HCN channel complex)","NA","NA","NA","hyperpolarization activated cyclic nucleotide gated potassium channel 1 [Source:HGNC Symbol;Acc:HGNC:4845]",{"v":0.00375087565674256,"d":"0.00"},{"v":0.0104822548161121,"d":"0.01"},{"v":0.357830993669144,"d":"0.36"},{"v":-1.48264974249967,"d":"-1.48"},1,1,"down","no"]
["ENSG00000260285","AL133367.1","ENST00000568177","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000228205","AC131235.1","ENST00000433853","NA","NA","NA","NA",null,{"v":0.140443,"d":"0.14"},{"v":0.022853,"d":"0.02"},{"v":6.14549512099068,"d":"6.15"},{"v":2.61952924816058,"d":"2.62"},1,1,"up","no"]
["ENSG00000272678","AC112503.1","ENST00000608436","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000136457","CHAD","ENST00000506187;ENST00000508540;ENST00000258969","GO:0005576(extracellular region);GO:0005578(proteinaceous extracellular matrix);GO:0005737(cytoplasm);GO:0004860(protein kinase inhibitor activity);GO:0006469(negative regulation of protein kinase activity);GO:0019221(cytokine-mediated signaling pathway);GO:0046426(negative regulation of JAK-STAT cascade);GO:0060348(bone development);GO:1900155(negative regulation of bone trabecula formation);GO:1900155(negative regulation of bone trabecula formation)","04151(PI3K-Akt signaling pathway);04512(ECM-receptor interaction);04510(Focal adhesion);05165(Human papillomavirus infection);05165(Human papillomavirus infection)","K06248","NA","chondroadherin [Source:HGNC Symbol;Acc:HGNC:1909]",{"v":0.805902427302997,"d":"0.81"},{"v":0.177904235849057,"d":"0.18"},{"v":4.52997885888881,"d":"4.53"},{"v":2.17950431732505,"d":"2.18"},1,1,"up","no"]
["ENSG00000255299","AP003557.1","ENST00000531715;ENST00000527054","NA","NA","NA","NA",null,0,{"v":0.101545624750499,"d":"0.10"},"-inf","-inf",1,1,"down","no"]
["ENSG00000268163","AC004076.1","ENST00000415705;ENST00000596831","GO:0003676(nucleic acid binding);GO:0006355(regulation of transcription, DNA-templated);GO:0005622(intracellular);GO:0005622(intracellular)","NA","NA","NA",null,0,{"v":0.0728552684824903,"d":"0.07"},"-inf","-inf",1,1,"down","no"]
["ENSG00000184350","MRGPRE","ENST00000389832","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0004930(G-protein coupled receptor activity);GO:0007186(G-protein coupled receptor signaling pathway);GO:0005886(plasma membrane);GO:0004871(signal transducer activity);GO:0007165(signal transduction);GO:0005887(integral component of plasma membrane);GO:1903955(positive regulation of protein targeting to mitochondrion)","NA","NA","NA","MAS related GPR family member E [Source:HGNC Symbol;Acc:HGNC:30694]",{"v":0.027239,"d":"0.03"},{"v":0.031085,"d":"0.03"},{"v":0.876274730577449,"d":"0.88"},{"v":-0.190544838870555,"d":"-0.19"},1,1,"down","no"]
["ENSG00000222033","LINC01124","ENST00000409786","NA","NA","NA","NA","long intergenic non-protein coding RNA 1124 [Source:HGNC Symbol;Acc:HGNC:49270]",{"v":0.048561,"d":"0.05"},0,"inf","inf",1,1,"up","no"]
["ENSG00000167653","PSCA","ENST00000301258;ENST00000505305","GO:0016020(membrane);GO:0005886(plasma membrane);GO:0031225(anchored component of membrane);GO:0005576(extracellular region);GO:0070062(extracellular exosome);GO:0006501(C-terminal protein lipidation);GO:0070373(negative regulation of ERK1 and ERK2 cascade);GO:0033130(acetylcholine receptor binding);GO:0099601(regulation of neurotransmitter receptor activity);GO:0099601(regulation of neurotransmitter receptor activity)","NA","NA","NA","prostate stem cell antigen [Source:HGNC Symbol;Acc:HGNC:9500]",{"v":0.144516585365854,"d":"0.14"},0,"inf","inf",1,1,"up","no"]
["ENSG00000250745","USP17L20","ENST00000613757;ENST00000506151","GO:0005634(nucleus);GO:0016579(protein deubiquitination);GO:0016787(hydrolase activity);GO:0005783(endoplasmic reticulum);GO:0008233(peptidase activity);GO:0008234(cysteine-type peptidase activity);GO:0006508(proteolysis);GO:0006511(ubiquitin-dependent protein catabolic process);GO:0036459(thiol-dependent ubiquitinyl hydrolase activity);GO:0036459(thiol-dependent ubiquitinyl hydrolase activity)","NA","NA","NA","ubiquitin specific peptidase 17-like family member 20 [Source:HGNC Symbol;Acc:HGNC:44448]",{"v":0.0430902357142857,"d":"0.04"},0,"inf","inf",1,1,"up","no"]
["ENSG00000255142","AP006621.2","ENST00000533938","NA","NA","NA","NA",null,{"v":0.319379,"d":"0.32"},{"v":0.149504,"d":"0.15"},{"v":2.13625722388699,"d":"2.14"},{"v":1.09508537047289,"d":"1.10"},1,1,"up","no"]
["ENSG00000181652","ATG9B","ENST00000617967;ENST00000404733;ENST00000469530","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0006914(autophagy);GO:0031410(cytoplasmic vesicle);GO:0000421(autophagosome membrane);GO:0000422(mitophagy);GO:0034497(protein localization to pre-autophagosomal structure);GO:0000407(pre-autophagosomal structure);GO:0005776(autophagosome);GO:0000045(autophagosome assembly);GO:0044805(late nucleophagy);GO:0005737(cytoplasm);GO:0005737(cytoplasm)","04140(Autophagy - animal);04136(Autophagy - other eukaryotes);04137(Mitophagy - animal);04137(Mitophagy - animal)","K17907","NA","autophagy related 9B [Source:HGNC Symbol;Acc:HGNC:21899]",{"v":0.217307527304021,"d":"0.22"},{"v":0.0885756754811454,"d":"0.09"},{"v":2.45335444661981,"d":"2.45"},{"v":1.29475568128231,"d":"1.29"},1,1,"up","no"]
["ENSG00000275445","AC092119.3","ENST00000612618","NA","NA","NA","NA",null,{"v":0.430261,"d":"0.43"},{"v":0.140863,"d":"0.14"},{"v":3.05446426669885,"d":"3.05"},{"v":1.6109193628415,"d":"1.61"},1,1,"up","no"]
["ENSG00000143512","HHIPL2","ENST00000343410","GO:0003824(catalytic activity);GO:0005515(protein binding);GO:0005576(extracellular region)","NA","NA","NA","HHIP like 2 [Source:HGNC Symbol;Acc:HGNC:25842]",{"v":0.0156653010033445,"d":"0.02"},{"v":0.0453306476132563,"d":"0.05"},{"v":0.345578583765113,"d":"0.35"},{"v":-1.53291428147518,"d":"-1.53"},1,1,"down","no"]
["ENSG00000132825","PPP1R3D","ENST00000370996","GO:0006470(protein dephosphorylation);GO:0005975(carbohydrate metabolic process);GO:0004722(protein serine/threonine phosphatase activity);GO:0005977(glycogen metabolic process);GO:0004721(phosphoprotein phosphatase activity);GO:0019899(enzyme binding);GO:0005979(regulation of glycogen biosynthetic process);GO:0005981(regulation of glycogen catabolic process);GO:0042587(glycogen granule);GO:0043231(intracellular membrane-bounded organelle)","04910(Insulin signaling pathway);04931(Insulin resistance)","K07189","NA","protein phosphatase 1 regulatory subunit 3D [Source:HGNC Symbol;Acc:HGNC:9294]",{"v":1.477109,"d":"1.48"},0,"inf","inf",1,1,"up","no"]
["ENSG00000229311","BX088651.2","ENST00000425493","NA","NA","NA","NA",null,{"v":0.006366,"d":"0.01"},0,"inf","inf",1,1,"up","no"]
["ENSG00000253227","AC090192.2","ENST00000517482","NA","NA","NA","NA",null,0,{"v":0.082502,"d":"0.08"},"-inf","-inf",1,1,"down","no"]
["MSTRG.12815","MCCD1P2","ENST00000423228","NA","NA","NA","NA","mitochondrial coiled-coil domain 1 pseudogene 2 [Source:HGNC Symbol;Acc:HGNC:33462]",0,{"v":0.257854,"d":"0.26"},"-inf","-inf",1,1,"down","no"]
["ENSG00000261202","Z83847.1","ENST00000569912","NA","NA","NA","NA",null,0,{"v":0.031185,"d":"0.03"},"-inf","-inf",1,1,"down","no"]
["ENSG00000236140","AC245014.1","ENST00000427732","NA","NA","NA","NA",null,{"v":0.848886,"d":"0.85"},{"v":0.051891,"d":"0.05"},{"v":16.3590217956871,"d":"16.36"},{"v":4.03201457833182,"d":"4.03"},1,1,"up","no"]
["ENSG00000224678","GAPDHP46","ENST00000424043","NA","NA","NA","NA","glyceraldehyde 3 phosphate dehydrogenase pseudogene 46 [Source:HGNC Symbol;Acc:HGNC:37804]",0,{"v":0.183597,"d":"0.18"},"-inf","-inf",1,1,"down","no"]
["ENSG00000183150","GPR19","ENST00000332427;ENST00000540796;ENST00000540510;ENST00000545876;ENST00000537507","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0004930(G-protein coupled receptor activity);GO:0007186(G-protein coupled receptor signaling pathway);GO:0005886(plasma membrane);GO:0004871(signal transducer activity);GO:0007165(signal transduction);GO:0005887(integral component of plasma membrane);GO:0007268(chemical synaptic transmission);GO:0007631(feeding behavior);GO:0007218(neuropeptide signaling pathway);GO:0007218(neuropeptide signaling pathway)","NA","NA","NA","G protein-coupled receptor 19 [Source:HGNC Symbol;Acc:HGNC:4473]",{"v":0.0572756256195196,"d":"0.06"},{"v":0.142302130385055,"d":"0.14"},{"v":0.402493100170304,"d":"0.40"},{"v":-1.31296404317665,"d":"-1.31"},1,1,"down","no"]
["ENSG00000277501","AC243571.2","ENST00000615265","NA","NA","NA","NA",null,0,{"v":0.036770403652968,"d":"0.04"},"-inf","-inf",1,1,"down","no"]
["MSTRG.8904","LINC01943","ENST00000625410;ENST00000628090","NA","NA","NA","NA","long intergenic non-protein coding RNA 1943 [Source:HGNC Symbol;Acc:HGNC:52767]",{"v":0.0435753627118644,"d":"0.04"},{"v":0.370042840677966,"d":"0.37"},{"v":0.117757615934492,"d":"0.12"},{"v":-3.08610772621185,"d":"-3.09"},1,1,"down","no"]
["ENSG00000230266","XXYLT1-AS2","ENST00000426468;ENST00000447975","NA","NA","NA","NA","XXYLT1 antisense RNA 2 [Source:HGNC Symbol;Acc:HGNC:41154]",0,{"v":0.137874,"d":"0.14"},"-inf","-inf",1,1,"down","no"]
["MSTRG.12661","AL139095.4","ENST00000379928","NA","NA","NA","NA",null,{"v":0.102247,"d":"0.10"},{"v":0.026657,"d":"0.03"},{"v":3.83565292418502,"d":"3.84"},{"v":1.93947218145853,"d":"1.94"},1,1,"up","no"]
["ENSG00000251637","AP003716.1","ENST00000529069;ENST00000533670;ENST00000511677","NA","NA","NA","NA",null,{"v":0.0634850148914689,"d":"0.06"},{"v":0.0566941711256941,"d":"0.06"},{"v":1.11978028130474,"d":"1.12"},{"v":0.16321568034631,"d":"0.16"},1,1,"up","no"]
["ENSG00000253552","HOXA-AS2","ENST00000517550;ENST00000523364;ENST00000517635","NA","NA","NA","NA","HOXA cluster antisense RNA 2 [Source:HGNC Symbol;Acc:HGNC:43745]",{"v":0.0179959532285552,"d":"0.02"},{"v":0.0192335311494035,"d":"0.02"},{"v":0.935655189302736,"d":"0.94"},{"v":-0.0959511338114912,"d":"-0.10"},1,1,"down","no"]
["ENSG00000147642","SYBU","ENST00000533065;ENST00000399066","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0043231(intracellular membrane-bounded organelle);GO:0005794(Golgi apparatus);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0000139(Golgi membrane);GO:0005874(microtubule);GO:0031410(cytoplasmic vesicle);GO:0019894(kinesin binding);GO:0017075(syntaxin-1 binding);GO:0031982(vesicle);GO:0008017(microtubule binding);GO:0061178(regulation of insulin secretion involved in cellular response to glucose stimulus);GO:0097433(dense body);GO:0097433(dense body)","NA","NA","NA","syntabulin [Source:HGNC Symbol;Acc:HGNC:26011]",{"v":0.0329802057232346,"d":"0.03"},{"v":0.0748056904897494,"d":"0.07"},{"v":0.44087830093292,"d":"0.44"},{"v":-1.18154762248539,"d":"-1.18"},1,1,"down","no"]
["ENSG00000274628","AL669942.1","ENST00000618309;ENST00000620585","NA","NA","NA","NA",null,{"v":0.0226901431276032,"d":"0.02"},{"v":0.0186572586141613,"d":"0.02"},{"v":1.21615632804601,"d":"1.22"},{"v":0.282328688650538,"d":"0.28"},1,1,"up","no"]
["MSTRG.8536","AC012065.2","ENST00000421295","NA","NA","NA","NA",null,{"v":0.133874,"d":"0.13"},0,"inf","inf",1,1,"up","no"]
["MSTRG.324","AL353622.1","ENST00000604716","NA","NA","NA","NA",null,{"v":0.282601,"d":"0.28"},{"v":0.207829,"d":"0.21"},{"v":1.35977654706514,"d":"1.36"},{"v":0.443369591970065,"d":"0.44"},1,1,"up","no"]
["ENSG00000251576","LINC01267","ENST00000502417","NA","NA","NA","NA","long intergenic non-protein coding RNA 1267 [Source:HGNC Symbol;Acc:HGNC:50320]",{"v":0.011253,"d":"0.01"},0,"inf","inf",1,1,"up","no"]
["ENSG00000255359","CCDC179","ENST00000532798","NA","NA","NA","NA","coiled-coil domain containing 179 [Source:HGNC Symbol;Acc:HGNC:44653]",0,{"v":0.0129561832061069,"d":"0.01"},"-inf","-inf",1,1,"down","no"]
["ENSG00000005108","THSD7A","ENST00000423059","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005886(plasma membrane);GO:0005576(extracellular region);GO:0030154(cell differentiation);GO:0070062(extracellular exosome);GO:0001525(angiogenesis)","NA","NA","NA","thrombospondin type 1 domain containing 7A [Source:HGNC Symbol;Acc:HGNC:22207]",{"v":0.0431886135968524,"d":"0.04"},{"v":0.0140729354927258,"d":"0.01"},{"v":3.06891292290626,"d":"3.07"},{"v":1.61772771146958,"d":"1.62"},1,1,"up","no"]
["ENSG00000258987","AL132642.1","ENST00000557646","NA","NA","NA","NA",null,{"v":0.105208,"d":"0.11"},0,"inf","inf",1,1,"up","no"]
["ENSG00000229646","AL109914.1","ENST00000414740","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000279742","AP000974.1","ENST00000623909","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000187498","COL4A1","ENST00000474391;ENST00000375820","GO:0005515(protein binding);GO:0005576(extracellular region);GO:0005581(collagen trimer);GO:0005578(proteinaceous extracellular matrix);GO:0005201(extracellular matrix structural constituent);GO:0005604(basement membrane);GO:0031012(extracellular matrix);GO:0030574(collagen catabolic process);GO:0005788(endoplasmic reticulum lumen);GO:0030198(extracellular matrix organization);GO:0001525(angiogenesis);GO:0001569(branching involved in blood vessel morphogenesis);GO:0061304(retinal blood vessel morphogenesis);GO:0048407(platelet-derived growth factor binding);GO:0030023(extracellular matrix constituent conferring elasticity);GO:0007420(brain development);GO:0007528(neuromuscular junction development);GO:0030855(epithelial cell differentiation);GO:0038063(collagen-activated tyrosine kinase receptor signaling pathway);GO:0048514(blood vessel morphogenesis);GO:0061333(renal tubule morphogenesis);GO:0071230(cellular response to amino acid stimulus);GO:0071711(basement membrane organization);GO:0005587(collagen type IV trimer);GO:0005615(extracellular space);GO:0005615(extracellular space)","04151(PI3K-Akt signaling pathway);04512(ECM-receptor interaction);04510(Focal adhesion);04926(Relaxin signaling pathway);04974(Protein digestion and absorption);05200(Pathways in cancer);05222(Small cell lung cancer);04933(AGE-RAGE signaling pathway in diabetic complications);05165(Human papillomavirus infection);05146(Amoebiasis);05146(Amoebiasis)","K06237","NA","collagen type IV alpha 1 chain [Source:HGNC Symbol;Acc:HGNC:2202]",{"v":0.0300946619443087,"d":"0.03"},{"v":0.0418620786516854,"d":"0.04"},{"v":0.718900324914875,"d":"0.72"},{"v":-0.476136339131679,"d":"-0.48"},1,1,"down","no"]
["ENSG00000221989","OR2A2","ENST00000408979","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0004930(G-protein coupled receptor activity);GO:0007186(G-protein coupled receptor signaling pathway);GO:0005886(plasma membrane);GO:0004871(signal transducer activity);GO:0007165(signal transduction);GO:0004984(olfactory receptor activity);GO:0007608(sensory perception of smell);GO:0050896(response to stimulus);GO:0050911(detection of chemical stimulus involved in sensory perception of smell)","04740(Olfactory transduction)","K04257","NA","olfactory receptor family 2 subfamily A member 2 [Source:HGNC Symbol;Acc:HGNC:8230]",0,{"v":0.13023,"d":"0.13"},"-inf","-inf",1,1,"down","no"]
["MSTRG.13117","B3GAT2","ENST00000230053","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0046872(metal ion binding);GO:0016740(transferase activity);GO:0005794(Golgi apparatus);GO:0000139(Golgi membrane);GO:0006486(protein glycosylation);GO:0015018(galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity);GO:0030203(glycosaminoglycan metabolic process);GO:0005975(carbohydrate metabolic process);GO:0030204(chondroitin sulfate metabolic process);GO:0050650(chondroitin sulfate proteoglycan biosynthetic process)","00515(Mannose type O-glycan biosyntheis)","K10157","EC:2.4.1.135","beta-1,3-glucuronyltransferase 2 [Source:HGNC Symbol;Acc:HGNC:922]",{"v":0.029375,"d":"0.03"},{"v":0.125387,"d":"0.13"},{"v":0.234274685573465,"d":"0.23"},{"v":-2.09372702190989,"d":"-2.09"},1,1,"down","no"]
["MSTRG.12504","AC009185.1","ENST00000517634","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000186230","ZNF749","ENST00000597296;ENST00000415248;ENST00000334181","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0005622(intracellular);GO:0005622(intracellular)","NA","NA","NA","zinc finger protein 749 [Source:HGNC Symbol;Acc:HGNC:32783]",{"v":0.113696806430229,"d":"0.11"},{"v":0.630951461054027,"d":"0.63"},{"v":0.180198974799574,"d":"0.18"},{"v":-2.47233729159261,"d":"-2.47"},1,1,"down","no"]
["ENSG00000232046","LINC01798","ENST00000433396","NA","NA","NA","NA","long intergenic non-protein coding RNA 1798 [Source:HGNC Symbol;Acc:HGNC:52588]",{"v":0.0106620323584319,"d":"0.01"},{"v":0.00132495581829496,"d":"0.00"},{"v":8.04708520179375,"d":"8.05"},{"v":3.00846630789578,"d":"3.01"},1,1,"up","no"]
["ENSG00000231513","E2F6P4","ENST00000468625","NA","NA","NA","NA","E2F transcription factor 6 pseudogene 4 [Source:HGNC Symbol;Acc:HGNC:51452]",{"v":0.50002,"d":"0.50"},{"v":0.177525,"d":"0.18"},{"v":2.81661737783411,"d":"2.82"},{"v":1.49396359474119,"d":"1.49"},1,1,"up","no"]
["MSTRG.6691","CCT6B","ENST00000436961;ENST00000314144;ENST00000421975;ENST00000577307;ENST00000585073","GO:0005737(cytoplasm);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0005829(cytosol);GO:0006457(protein folding);GO:0051082(unfolded protein binding);GO:0061077(chaperone-mediated protein folding);GO:0007283(spermatogenesis);GO:0051131(chaperone-mediated protein complex assembly);GO:0044183(protein binding involved in protein folding);GO:0006458('de novo' protein folding);GO:0005832(chaperonin-containing T-complex);GO:0015031(protein transport);GO:0008565(protein transporter activity);GO:1901998(toxin transport);GO:1901998(toxin transport)","NA","NA","NA","chaperonin containing TCP1 subunit 6B [Source:HGNC Symbol;Acc:HGNC:1621]",{"v":0.0801384533917859,"d":"0.08"},{"v":0.0316973987078911,"d":"0.03"},{"v":2.52823438700146,"d":"2.53"},{"v":1.338130218772,"d":"1.34"},1,1,"up","no"]
["ENSG00000205488","CALML3-AS1","ENST00000543008","NA","NA","NA","NA","CALML3 antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:44682]",{"v":0.0202423401303342,"d":"0.02"},0,"inf","inf",1,1,"up","no"]
["ENSG00000239388","ASB14","ENST00000487349","GO:0016567(protein ubiquitination);GO:0035556(intracellular signal transduction);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0004842(ubiquitin-protein transferase activity);GO:0031625(ubiquitin protein ligase binding);GO:0000151(ubiquitin ligase complex);GO:0005829(cytosol);GO:0043687(post-translational protein modification)","NA","NA","NA","ankyrin repeat and SOCS box containing 14 [Source:HGNC Symbol;Acc:HGNC:19766]",{"v":0.267185507425743,"d":"0.27"},{"v":0.176269254950495,"d":"0.18"},{"v":1.51578054551136,"d":"1.52"},{"v":0.600060895448036,"d":"0.60"},1,1,"up","no"]
["MSTRG.3291","AC093012.1","ENST00000548437;ENST00000549403","NA","NA","NA","NA",null,{"v":0.0190765384615385,"d":"0.02"},0,"inf","inf",1,1,"up","no"]
["ENSG00000253595","LINC01300","ENST00000521073","NA","NA","NA","NA","long intergenic non-protein coding RNA 1300 [Source:HGNC Symbol;Acc:HGNC:50460]",0,0,1,0,1,1,"no","no"]
["MSTRG.1921","AL133215.1","ENST00000447344","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000106689","LHX2","ENST00000373615","GO:0046872(metal ion binding);GO:0005634(nucleus);GO:0006355(regulation of transcription, DNA-templated);GO:0006366(transcription from RNA polymerase II promoter);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0043565(sequence-specific DNA binding);GO:0045893(positive regulation of transcription, DNA-templated);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:0001076(transcription factor activity, RNA polymerase II transcription factor binding);GO:0001077(transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0003682(chromatin binding);GO:0001843(neural tube closure);GO:0001942(hair follicle development);GO:0007399(nervous system development);GO:0007411(axon guidance);GO:0007420(brain development);GO:0007498(mesoderm development);GO:0009953(dorsal/ventral pattern formation);GO:0021537(telencephalon development);GO:0021772(olfactory bulb development);GO:0021978(telencephalon regionalization);GO:0021987(cerebral cortex development);GO:0022008(neurogenesis);GO:0030182(neuron differentiation);GO:0045199(maintenance of epithelial cell apical/basal polarity);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0048646(anatomical structure formation involved in morphogenesis);GO:0048675(axon extension);GO:0060041(retina development in camera-type eye);GO:2000678(negative regulation of transcription regulatory region DNA binding);GO:0005622(intracellular)","NA","NA","NA","LIM homeobox 2 [Source:HGNC Symbol;Acc:HGNC:6594]",{"v":0.0138877958568738,"d":"0.01"},{"v":0.0171844278719397,"d":"0.02"},{"v":0.808161665920287,"d":"0.81"},{"v":-0.307284174074136,"d":"-0.31"},1,1,"down","no"]
["ENSG00000265752","AC010754.1","ENST00000582300","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000182824","LINC01662","ENST00000342888","NA","NA","NA","NA","long intergenic non-protein coding RNA 1662 [Source:HGNC Symbol;Acc:HGNC:52450]",0,{"v":0.000668369565217391,"d":"0.00"},"-inf","-inf",1,1,"down","no"]
["MSTRG.6022","AC027682.7","ENST00000623147","NA","NA","NA","NA",null,0,{"v":0.083533,"d":"0.08"},"-inf","-inf",1,1,"down","no"]
["ENSG00000276529","AP001505.2","ENST00000616815","NA","NA","NA","NA",null,{"v":1.118159,"d":"1.12"},{"v":1.124633,"d":"1.12"},{"v":0.994243455420568,"d":"0.99"},{"v":-0.00832893432493313,"d":"-0.01"},1,1,"down","no"]
["ENSG00000182632","CCNYL2","ENST00000637719;ENST00000472090","NA","NA","NA","NA","cyclin Y-like 2 (pseudogene) [Source:HGNC Symbol;Acc:HGNC:23495]",0,{"v":0.0310671874184286,"d":"0.03"},"-inf","-inf",1,1,"down","no"]
["ENSG00000122543","OCM","ENST00000242104;ENST00000416608","GO:0046872(metal ion binding);GO:0005509(calcium ion binding);GO:0005509(calcium ion binding)","NA","NA","NA","oncomodulin [Source:HGNC Symbol;Acc:HGNC:8105]",{"v":0.517997199519231,"d":"0.52"},{"v":0.169060420673077,"d":"0.17"},{"v":3.06397675728558,"d":"3.06"},{"v":1.61540535330856,"d":"1.62"},1,1,"up","no"]
["ENSG00000276770","MIR6780B","ENST00000610307","NA","NA","NA","NA","microRNA 6780b [Source:HGNC Symbol;Acc:HGNC:50237]",0,0,1,0,1,1,"no","no"]
["ENSG00000284237","AL356275.1","ENST00000638446","NA","NA","NA","NA",null,{"v":0.0064,"d":"0.01"},0,"inf","inf",1,1,"up","no"]
["ENSG00000255434","AP001922.6","ENST00000532553","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000134042","MRO","ENST00000256425;ENST00000590988","GO:0005634(nucleus);GO:0005730(nucleolus);GO:0005730(nucleolus)","NA","NA","NA","maestro [Source:HGNC Symbol;Acc:HGNC:24121]",{"v":0.0223998734841629,"d":"0.02"},0,"inf","inf",1,1,"up","no"]
["ENSG00000152207","CYSLTR2","ENST00000614739;ENST00000617562;ENST00000282018;ENST00000622559","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0004930(G-protein coupled receptor activity);GO:0007186(G-protein coupled receptor signaling pathway);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0004871(signal transducer activity);GO:0007165(signal transduction);GO:0006955(immune response);GO:0005887(integral component of plasma membrane);GO:0005575(cellular_component);GO:0004974(leukotriene receptor activity);GO:0061737(leukotriene signaling pathway);GO:0007200(phospholipase C-activating G-protein coupled receptor signaling pathway);GO:0007218(neuropeptide signaling pathway);GO:0008528(G-protein coupled peptide receptor activity);GO:0001631(cysteinyl leukotriene receptor activity);GO:0010942(positive regulation of cell death);GO:0045766(positive regulation of angiogenesis);GO:0070374(positive regulation of ERK1 and ERK2 cascade);GO:0070374(positive regulation of ERK1 and ERK2 cascade)","04020(Calcium signaling pathway);04080(Neuroactive ligand-receptor interaction);04080(Neuroactive ligand-receptor interaction)","K04323","NA","cysteinyl leukotriene receptor 2 [Source:HGNC Symbol;Acc:HGNC:18274]",{"v":0.0799788857036485,"d":"0.08"},{"v":0.735662003909159,"d":"0.74"},{"v":0.108716890744196,"d":"0.11"},{"v":-3.20135199353028,"d":"-3.20"},1,1,"down","no"]
["ENSG00000253495","CYCSP23","ENST00000519781","NA","NA","NA","NA","cytochrome c, somatic pseudogene 23 [Source:HGNC Symbol;Acc:HGNC:24397]",{"v":0.082112,"d":"0.08"},0,"inf","inf",1,1,"up","no"]
["ENSG00000267130","AC008738.2","ENST00000593041","NA","NA","NA","NA",null,0,{"v":0.093589,"d":"0.09"},"-inf","-inf",1,1,"down","no"]
["ENSG00000134240","HMGCS2","ENST00000472375;ENST00000369406","GO:0016740(transferase activity);GO:0005739(mitochondrion);GO:0003824(catalytic activity);GO:0006629(lipid metabolic process);GO:0008152(metabolic process);GO:0004421(hydroxymethylglutaryl-CoA synthase activity);GO:0006694(steroid biosynthetic process);GO:0008202(steroid metabolic process);GO:0008299(isoprenoid biosynthetic process);GO:0016126(sterol biosynthetic process);GO:0008203(cholesterol metabolic process);GO:0005743(mitochondrial inner membrane);GO:0006695(cholesterol biosynthetic process);GO:0005759(mitochondrial matrix);GO:0019216(regulation of lipid metabolic process);GO:0046951(ketone body biosynthetic process);GO:0046951(ketone body biosynthetic process)","00650(Butanoate metabolism);00072(Synthesis and degradation of ketone bodies);00280(Valine, leucine and isoleucine degradation);00900(Terpenoid backbone biosynthesis);03320(PPAR signaling pathway);03320(PPAR signaling pathway)","K01641","EC:2.3.3.10","3-hydroxy-3-methylglutaryl-CoA synthase 2 [Source:HGNC Symbol;Acc:HGNC:5008]",{"v":5.57183975106962E-3,"d":"0.01"},{"v":0.0487004636328277,"d":"0.05"},{"v":0.114410404654008,"d":"0.11"},{"v":-3.1277098359514,"d":"-3.13"},1,1,"down","no"]
["ENSG00000254737","OR10G4","ENST00000320891","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0004930(G-protein coupled receptor activity);GO:0007186(G-protein coupled receptor signaling pathway);GO:0005886(plasma membrane);GO:0004871(signal transducer activity);GO:0007165(signal transduction);GO:0004984(olfactory receptor activity);GO:0007608(sensory perception of smell);GO:0050896(response to stimulus);GO:0050911(detection of chemical stimulus involved in sensory perception of smell)","04740(Olfactory transduction)","K04257","NA","olfactory receptor family 10 subfamily G member 4 [Source:HGNC Symbol;Acc:HGNC:14809]",{"v":0.0107354523875242,"d":"0.01"},{"v":0.025185711288987,"d":"0.03"},{"v":0.426251705355588,"d":"0.43"},{"v":-1.2302224887784,"d":"-1.23"},1,1,"down","no"]
["ENSG00000235268","KDM4E","ENST00000450979","GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0016569(covalent chromatin modification);GO:0051213(dioxygenase activity);GO:0032454(histone demethylase activity (H3-K9 specific));GO:0033169(histone H3-K9 demethylation)","NA","NA","NA","lysine demethylase 4E [Source:HGNC Symbol;Acc:HGNC:37098]",{"v":0.021976,"d":"0.02"},{"v":0.043888,"d":"0.04"},{"v":0.500729128691214,"d":"0.50"},{"v":-0.997897711772421,"d":"-1.00"},1,1,"down","no"]
["MSTRG.13700","PHBP5","ENST00000449310","NA","NA","NA","NA","prohibitin pseudogene 5 [Source:HGNC Symbol;Acc:HGNC:39284]",0,{"v":0.019802,"d":"0.02"},"-inf","-inf",1,1,"down","no"]
["ENSG00000267881","AC243967.1","ENST00000435837;ENST00000598976","NA","NA","NA","NA",null,{"v":0.00835605865921788,"d":"0.01"},{"v":0.0278076913407821,"d":"0.03"},{"v":0.300494512716454,"d":"0.30"},{"v":-1.73458944854005,"d":"-1.73"},1,1,"down","no"]
["MSTRG.11589","AC098869.2","ENST00000514187","NA","NA","NA","NA",null,{"v":0.065969,"d":"0.07"},{"v":0.068648,"d":"0.07"},{"v":0.960974828108612,"d":"0.96"},{"v":-0.0574294535225672,"d":"-0.06"},1,1,"down","no"]
["ENSG00000254818","AP004607.3","ENST00000530354","NA","NA","NA","NA",null,{"v":0.006565,"d":"0.01"},0,"inf","inf",1,1,"up","no"]
["MSTRG.4868","TJP1","ENST00000495972;ENST00000558447;ENST00000561307;ENST00000346128","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0030054(cell junction);GO:0005515(protein binding);GO:0005921(gap junction);GO:0005923(bicellular tight junction);GO:0005516(calmodulin binding);GO:0045296(cadherin binding);GO:2000810(regulation of bicellular tight junction assembly);GO:0035329(hippo signaling);GO:0016323(basolateral plasma membrane);GO:0007043(cell-cell junction assembly);GO:0090557(establishment of endothelial intestinal barrier);GO:1901350(cell-cell signaling involved in cell-cell junction organization);GO:0005913(cell-cell adherens junction);GO:0043296(apical junction complex);GO:0045177(apical part of cell);GO:0008022(protein C-terminus binding);GO:0019904(protein domain specific binding);GO:0071253(connexin binding);GO:0001825(blastocyst formation);GO:0007605(sensory perception of sound);GO:0032496(response to lipopolysaccharide);GO:0042493(response to drug);GO:0043116(negative regulation of vascular permeability);GO:0045471(response to ethanol);GO:0071000(response to magnetism);GO:0071333(cellular response to glucose stimulus);GO:0005634(nucleus);GO:0005911(cell-cell junction);GO:0005912(adherens junction);GO:0014704(intercalated disc);GO:0016324(apical plasma membrane);GO:0016327(apicolateral plasma membrane);GO:0043234(protein complex);GO:0046581(intercellular canaliculus);GO:0070160(occluding junction);GO:0070160(occluding junction)","04520(Adherens junction);04530(Tight junction);04540(Gap junction);05110(Vibrio cholerae infection);05120(Epithelial cell signaling in Helicobacter pylori infection);05132(Salmonella infection);05132(Salmonella infection)","K05701","NA","tight junction protein 1 [Source:HGNC Symbol;Acc:HGNC:11827]",{"v":0.0206497274744785,"d":"0.02"},{"v":0.0124694948956946,"d":"0.01"},{"v":1.65601956191572,"d":"1.66"},{"v":0.727719714933926,"d":"0.73"},1,1,"up","no"]
["ENSG00000176399","DMRTA1","ENST00000325870","GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0043565(sequence-specific DNA binding);GO:0042803(protein homodimerization activity);GO:0001541(ovarian follicle development);GO:0060179(male mating behavior)","NA","NA","NA","DMRT like family A1 [Source:HGNC Symbol;Acc:HGNC:13826]",0,{"v":0.016167,"d":"0.02"},"-inf","-inf",1,1,"down","no"]
["ENSG00000182898","TCHHL1","ENST00000368806","GO:0046914(transition metal ion binding)","NA","NA","NA","trichohyalin like 1 [Source:HGNC Symbol;Acc:HGNC:31796]",{"v":0.020405,"d":"0.02"},{"v":0.012663,"d":"0.01"},{"v":1.61138750690989,"d":"1.61"},{"v":0.688303475466618,"d":"0.69"},1,1,"up","no"]
["ENSG00000237400","AC006960.2","ENST00000435254","NA","NA","NA","NA",null,{"v":0.035633,"d":"0.04"},{"v":0.059155,"d":"0.06"},{"v":0.60236666384921,"d":"0.60"},{"v":-0.731286164237097,"d":"-0.73"},1,1,"down","no"]
["ENSG00000236849","LINC01474","ENST00000449235","NA","NA","NA","NA","long intergenic non-protein coding RNA 1474 [Source:HGNC Symbol;Acc:HGNC:51111]",0,0,1,0,1,1,"no","no"]
["ENSG00000107518","ATRNL1","ENST00000616894;ENST00000355044","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0030246(carbohydrate binding);GO:0007186(G-protein coupled receptor signaling pathway);GO:0007186(G-protein coupled receptor signaling pathway)","NA","NA","NA","attractin like 1 [Source:HGNC Symbol;Acc:HGNC:29063]",{"v":0.000365950325732899,"d":"0.00"},{"v":0.00640453929153094,"d":"0.01"},{"v":0.0571392115927549,"d":"0.06"},{"v":-4.12937505967947,"d":"-4.13"},1,1,"down","no"]
["ENSG00000224905","AP001347.1","ENST00000428809","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000262185","AC005736.1","ENST00000576810","NA","NA","NA","NA",null,{"v":0.109638,"d":"0.11"},{"v":0.089349,"d":"0.09"},{"v":1.22707584863848,"d":"1.23"},{"v":0.295224428359065,"d":"0.30"},1,1,"up","no"]
["MSTRG.5748","AC130448.1","ENST00000624179","NA","NA","NA","NA",null,{"v":0.029562,"d":"0.03"},0,"inf","inf",1,1,"up","no"]
["ENSG00000145692","BHMT","ENST00000274353","GO:0005737(cytoplasm);GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0005829(cytosol);GO:0008168(methyltransferase activity);GO:0016740(transferase activity);GO:0032259(methylation);GO:0047150(betaine-homocysteine S-methyltransferase activity);GO:0009086(methionine biosynthetic process);GO:0070062(extracellular exosome);GO:0000096(sulfur amino acid metabolic process);GO:0042426(choline catabolic process);GO:0006479(protein methylation);GO:0006577(amino-acid betaine metabolic process);GO:0006579(amino-acid betaine catabolic process);GO:0050666(regulation of homocysteine metabolic process);GO:0071267(L-methionine salvage)","00260(Glycine, serine and threonine metabolism);00270(Cysteine and methionine metabolism)","K00544","EC:2.1.1.5","betaine--homocysteine S-methyltransferase [Source:HGNC Symbol;Acc:HGNC:1047]",{"v":0.00243445524296675,"d":"0.00"},{"v":0.0194045421994885,"d":"0.02"},{"v":0.125458009673164,"d":"0.13"},{"v":-2.99472351455978,"d":"-2.99"},1,1,"down","no"]
["ENSG00000250771","AC106865.1","ENST00000507055;ENST00000602666","NA","NA","NA","NA",null,{"v":0.0799894610924626,"d":"0.08"},{"v":0.0309141721086359,"d":"0.03"},{"v":2.58746897090987,"d":"2.59"},{"v":1.37154156182631,"d":"1.37"},1,1,"up","no"]
["ENSG00000240859","AC093627.4","ENST00000492208;ENST00000484550;ENST00000471299","NA","NA","NA","NA",null,{"v":0.105019852398524,"d":"0.11"},{"v":0.107864637793746,"d":"0.11"},{"v":0.973626338961415,"d":"0.97"},{"v":-0.0385598978967039,"d":"-0.04"},1,1,"down","no"]
["ENSG00000255581","AC006511.2","ENST00000388966","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000229587","AL158825.2","ENST00000455336","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000267423","AC005616.1","ENST00000592931","NA","NA","NA","NA",null,{"v":0.024266,"d":"0.02"},0,"inf","inf",1,1,"up","no"]
["ENSG00000175664","TEX26","ENST00000380473","NA","NA","NA","NA","testis expressed 26 [Source:HGNC Symbol;Acc:HGNC:28622]",{"v":0.0738002795180723,"d":"0.07"},0,"inf","inf",1,1,"up","no"]
["ENSG00000226149","AL356124.1","ENST00000419061","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000144229","THSD7B","ENST00000409968","GO:0016020(membrane);GO:0016021(integral component of membrane)","NA","NA","NA","thrombospondin type 1 domain containing 7B [Source:HGNC Symbol;Acc:HGNC:29348]",{"v":0.0380875621118012,"d":"0.04"},{"v":0.00786784472049689,"d":"0.01"},{"v":4.84091431196875,"d":"4.84"},{"v":2.27527955757579,"d":"2.28"},1,1,"up","no"]
["ENSG00000257074","RPL29P33","ENST00000587474","NA","NA","NA","NA","ribosomal protein L29 pseudogene 33 [Source:HGNC Symbol;Acc:HGNC:36923]",0,{"v":0.060639,"d":"0.06"},"-inf","-inf",1,1,"down","no"]
["ENSG00000124334","IL9R","ENST00000489233;ENST00000244174;ENST00000494962;ENST00000369423","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005886(plasma membrane);GO:0005576(extracellular region);GO:0004896(cytokine receptor activity);GO:0019221(cytokine-mediated signaling pathway);GO:0005887(integral component of plasma membrane);GO:0007165(signal transduction);GO:0005615(extracellular space);GO:0008283(cell proliferation);GO:1903955(positive regulation of protein targeting to mitochondrion);GO:0004919(interleukin-9 receptor activity);GO:0019983(interleukin-9 binding);GO:0030307(positive regulation of cell growth);GO:0038113(interleukin-9-mediated signaling pathway);GO:0038113(interleukin-9-mediated signaling pathway)","04630(Jak-STAT signaling pathway);04060(Cytokine-cytokine receptor interaction);04640(Hematopoietic cell lineage);04640(Hematopoietic cell lineage)","K05073","NA","interleukin 9 receptor [Source:HGNC Symbol;Acc:HGNC:6030]",{"v":0.258452164536741,"d":"0.26"},{"v":0.178313654952077,"d":"0.18"},{"v":1.44942441231549,"d":"1.45"},{"v":0.535480098614189,"d":"0.54"},1,1,"up","no"]
["ENSG00000259341","AC015660.1","ENST00000560103","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000233121","VN1R20P","ENST00000425215","NA","NA","NA","NA","vomeronasal 1 receptor 20 pseudogene [Source:HGNC Symbol;Acc:HGNC:37335]",0,0,1,0,1,1,"no","no"]
["ENSG00000177689","MAGEB10","ENST00000614159","NA","NA","NA","NA","MAGE family member B10 [Source:HGNC Symbol;Acc:HGNC:25377]",0,{"v":0.0467217496159754,"d":"0.05"},"-inf","-inf",1,1,"down","no"]
["ENSG00000154537","FAM27C","ENST00000377542","NA","NA","NA","NA","family with sequence similarity 27 member C [Source:HGNC Symbol;Acc:HGNC:23668]",{"v":0.390244,"d":"0.39"},{"v":0.222194,"d":"0.22"},{"v":1.7563210527737,"d":"1.76"},{"v":0.812556591403736,"d":"0.81"},1,1,"up","no"]
["ENSG00000236111","AL603882.1","ENST00000463059","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["MSTRG.5702","AF001548.1","ENST00000577048","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000182315","MBD3L3","ENST00000333843","GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0005634(nucleus);GO:0008327(methyl-CpG binding);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0006346(methylation-dependent chromatin silencing)","NA","NA","NA","methyl-CpG binding domain protein 3 like 3 [Source:HGNC Symbol;Acc:HGNC:37205]",{"v":0.038782,"d":"0.04"},{"v":0.052328,"d":"0.05"},{"v":0.741132854303623,"d":"0.74"},{"v":-0.432195913942086,"d":"-0.43"},1,1,"down","no"]
["ENSG00000007001","UPP2","ENST00000605860","GO:0005737(cytoplasm);GO:0016740(transferase activity);GO:0009116(nucleoside metabolic process);GO:0003824(catalytic activity);GO:0016757(transferase activity, transferring glycosyl groups);GO:0005829(cytosol);GO:0005515(protein binding);GO:0044206(UMP salvage);GO:0004850(uridine phosphorylase activity);GO:0016763(transferase activity, transferring pentosyl groups);GO:0009166(nucleotide catabolic process);GO:0043097(pyrimidine nucleoside salvage);GO:0046108(uridine metabolic process);GO:0046135(pyrimidine nucleoside catabolic process);GO:0045098(type III intermediate filament)","00240(Pyrimidine metabolism);00983(Drug metabolism - other enzymes)","K00757","EC:2.4.2.3","uridine phosphorylase 2 [Source:HGNC Symbol;Acc:HGNC:23061]",{"v":0.0129400033818059,"d":"0.01"},0,"inf","inf",1,1,"up","no"]
["ENSG00000234322","ST13P18","ENST00000456632","NA","NA","NA","NA","ST13, Hsp70 interacting protein pseudogene 18 [Source:HGNC Symbol;Acc:HGNC:38861]",{"v":0.025025,"d":"0.03"},0,"inf","inf",1,1,"up","no"]
["MSTRG.13591","TRGV9","ENST00000444775","GO:0005887(integral component of plasma membrane);GO:0042605(peptide antigen binding);GO:0042287(MHC protein binding)","NA","NA","NA","T-cell receptor gamma variable 9 [Source:HGNC Symbol;Acc:HGNC:12295]",{"v":0.598456,"d":"0.60"},0,"inf","inf",1,1,"up","no"]
["ENSG00000272823","AL445423.1","ENST00000609941","NA","NA","NA","NA",null,0,{"v":0.085119,"d":"0.09"},"-inf","-inf",1,1,"down","no"]
["ENSG00000183647","ZNF530","ENST00000598297;ENST00000600619;ENST00000332854;ENST00000597700","GO:0003676(nucleic acid binding);GO:0006355(regulation of transcription, DNA-templated);GO:0005622(intracellular);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0003677(DNA binding)","NA","NA","NA","zinc finger protein 530 [Source:HGNC Symbol;Acc:HGNC:29297]",{"v":0.16561056027097,"d":"0.17"},{"v":0.0738090900577804,"d":"0.07"},{"v":2.24376916368057,"d":"2.24"},{"v":1.16592426082042,"d":"1.17"},1,1,"up","no"]
["MSTRG.15109","CCDC183-AS1","ENST00000414656","NA","NA","NA","NA","CCDC183 antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:44105]",{"v":0.434889,"d":"0.43"},{"v":0.262262,"d":"0.26"},{"v":1.65822345593338,"d":"1.66"},{"v":0.729638432071719,"d":"0.73"},1,1,"up","no"]
["ENSG00000173227","SYT12","ENST00000531392;ENST00000393946","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0030054(cell junction);GO:0045202(synapse);GO:0031410(cytoplasmic vesicle);GO:0005886(plasma membrane);GO:0005509(calcium ion binding);GO:0005544(calcium-dependent phospholipid binding);GO:0019905(syntaxin binding);GO:0030276(clathrin binding);GO:0006906(vesicle fusion);GO:0017158(regulation of calcium ion-dependent exocytosis);GO:0048791(calcium ion-regulated exocytosis of neurotransmitter);GO:0046928(regulation of neurotransmitter secretion);GO:0060291(long-term synaptic potentiation);GO:0030672(synaptic vesicle membrane);GO:0048792(spontaneous exocytosis of neurotransmitter);GO:0048792(spontaneous exocytosis of neurotransmitter)","NA","NA","NA","synaptotagmin 12 [Source:HGNC Symbol;Acc:HGNC:18381]",{"v":0.0102703682363804,"d":"0.01"},{"v":0.0116116891966759,"d":"0.01"},{"v":0.884485285682682,"d":"0.88"},{"v":-0.177089952479487,"d":"-0.18"},1,1,"down","no"]
["ENSG00000229405","AC092580.1","ENST00000433998","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000185960","SHOX","ENST00000381578","GO:0005634(nucleus);GO:0043231(intracellular membrane-bounded organelle);GO:0005654(nucleoplasm);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0043565(sequence-specific DNA binding);GO:0005515(protein binding);GO:0007275(multicellular organism development);GO:0001228(transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0006366(transcription from RNA polymerase II promoter);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0001501(skeletal system development)","NA","NA","NA","short stature homeobox [Source:HGNC Symbol;Acc:HGNC:10853]",{"v":0.0366513175182482,"d":"0.04"},{"v":0.00651818932481752,"d":"0.01"},{"v":5.62292926636866,"d":"5.62"},{"v":2.49132189861249,"d":"2.49"},1,1,"up","no"]
["ENSG00000239626","RPSAP41","ENST00000439695","NA","NA","NA","NA","ribosomal protein SA pseudogene 41 [Source:HGNC Symbol;Acc:HGNC:36663]",{"v":0.105354,"d":"0.11"},0,"inf","inf",1,1,"up","no"]
["ENSG00000276368","HIST1H2AJ","ENST00000333151","GO:0005634(nucleus);GO:0003677(DNA binding);GO:0046982(protein heterodimerization activity);GO:0000786(nucleosome);GO:0005694(chromosome);GO:0000790(nuclear chromatin);GO:0003674(molecular_function);GO:0008150(biological_process);GO:0070062(extracellular exosome);GO:0006342(chromatin silencing)","04217(Necroptosis);05322(Systemic lupus erythematosus);05034(Alcoholism)","K11251","NA","histone cluster 1 H2A family member j [Source:HGNC Symbol;Acc:HGNC:4727]",{"v":0.066411,"d":"0.07"},0,"inf","inf",1,1,"up","no"]
["ENSG00000196724","ZNF418","ENST00000600353;ENST00000396147;ENST00000425570","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0005622(intracellular);GO:0005515(protein binding);GO:0045892(negative regulation of transcription, DNA-templated);GO:0045892(negative regulation of transcription, DNA-templated)","NA","NA","NA","zinc finger protein 418 [Source:HGNC Symbol;Acc:HGNC:20647]",{"v":0.127620013774717,"d":"0.13"},{"v":0.0793661061986225,"d":"0.08"},{"v":1.60799136920405,"d":"1.61"},{"v":0.685259662959669,"d":"0.69"},1,1,"up","no"]
["ENSG00000237872","POU5F1P4","ENST00000413175","NA","NA","NA","NA","POU class 5 homeobox 1 pseudogene 4 [Source:HGNC Symbol;Acc:HGNC:33310]",0,{"v":0.04205,"d":"0.04"},"-inf","-inf",1,1,"down","no"]
["ENSG00000250274","AC034199.1","ENST00000511921","NA","NA","NA","NA",null,{"v":0.201808,"d":"0.20"},{"v":0.020491,"d":"0.02"},{"v":9.84861646576546,"d":"9.85"},{"v":3.29992106891695,"d":"3.30"},1,1,"up","no"]
["ENSG00000279324","AL645730.1","ENST00000622945","NA","NA","NA","NA",null,{"v":0.02704,"d":"0.03"},0,"inf","inf",1,1,"up","no"]
["ENSG00000233041","PHGR1","ENST00000448599;ENST00000560745","NA","NA","NA","NA","proline, histidine and glycine rich 1 [Source:HGNC Symbol;Acc:HGNC:37226]",{"v":0.0419134537725824,"d":"0.04"},0,"inf","inf",1,1,"up","no"]
["MSTRG.2514","AP003774.4","ENST00000447028","NA","NA","NA","NA",null,{"v":0.305964,"d":"0.31"},{"v":0.271571,"d":"0.27"},{"v":1.12664459754539,"d":"1.13"},{"v":0.172032486031582,"d":"0.17"},1,1,"up","no"]
["ENSG00000266486","FAM106CP","ENST00000582212","NA","NA","NA","NA","family with sequence similarity 106 member C, pseudogene [Source:HGNC Symbol;Acc:HGNC:38396]",0,{"v":0.044994,"d":"0.04"},"-inf","-inf",1,1,"down","no"]
["ENSG00000232060","SLC4A1APP1","ENST00000419995","NA","NA","NA","NA","solute carrier family 4 member 1 adaptor protein pseudogene 1 [Source:HGNC Symbol;Acc:HGNC:49811]",{"v":0.438027,"d":"0.44"},{"v":0.064672,"d":"0.06"},{"v":6.77305479960416,"d":"6.77"},{"v":2.75980666839849,"d":"2.76"},1,1,"up","no"]
["ENSG00000259490","IGHV3OR15-7","ENST00000558565","GO:0003823(antigen binding);GO:0034987(immunoglobulin receptor binding);GO:0006910(phagocytosis, recognition);GO:0006911(phagocytosis, engulfment);GO:0006958(complement activation, classical pathway);GO:0042742(defense response to bacterium);GO:0045087(innate immune response);GO:0050853(B cell receptor signaling pathway);GO:0050871(positive regulation of B cell activation);GO:0009897(external side of plasma membrane);GO:0042571(immunoglobulin complex, circulating);GO:0072562(blood microparticle)","NA","NA","NA","immunoglobulin heavy variable 3/OR15-7 (pseudogene) [Source:HGNC Symbol;Acc:HGNC:5633]",0,{"v":0.074166,"d":"0.07"},"-inf","-inf",1,1,"down","no"]
["ENSG00000224376","AC017104.1","ENST00000415129;ENST00000454416;ENST00000418050","NA","NA","NA","NA",null,{"v":0.188828148403256,"d":"0.19"},{"v":0.199979683782091,"d":"0.20"},{"v":0.94423665860485,"d":"0.94"},{"v":-0.0827796003369249,"d":"-0.08"},1,1,"down","no"]
["ENSG00000130224","LRCH2","ENST00000317135","GO:0005886(plasma membrane);GO:0007165(signal transduction)","NA","NA","NA","leucine rich repeats and calponin homology domain containing 2 [Source:HGNC Symbol;Acc:HGNC:29292]",{"v":0.009525,"d":"0.01"},0,"inf","inf",1,1,"up","no"]
["ENSG00000226933","NRBF2P2","ENST00000413087","NA","NA","NA","NA","nuclear receptor binding factor 2 pseudogene 2 [Source:HGNC Symbol;Acc:HGNC:44605]",0,0,1,0,1,1,"no","no"]
["ENSG00000137080","IFNA21","ENST00000380225","GO:0005576(extracellular region);GO:0005125(cytokine activity);GO:0005615(extracellular space);GO:0006952(defense response);GO:0045087(innate immune response);GO:0005126(cytokine receptor binding);GO:0051607(defense response to virus);GO:0019221(cytokine-mediated signaling pathway);GO:0060337(type I interferon signaling pathway);GO:0007596(blood coagulation);GO:0002250(adaptive immune response);GO:0005132(type I interferon receptor binding);GO:0002286(T cell activation involved in immune response);GO:0002323(natural killer cell activation involved in immune response);GO:0006959(humoral immune response);GO:0030183(B cell differentiation);GO:0033141(positive regulation of peptidyl-serine phosphorylation of STAT protein);GO:0042100(B cell proliferation);GO:0043330(response to exogenous dsRNA);GO:0060338(regulation of type I interferon-mediated signaling pathway)","04630(Jak-STAT signaling pathway);04151(PI3K-Akt signaling pathway);04060(Cytokine-cytokine receptor interaction);04217(Necroptosis);04620(Toll-like receptor signaling pathway);04621(NOD-like receptor signaling pathway);04622(RIG-I-like receptor signaling pathway);04623(Cytosolic DNA-sensing pathway);04650(Natural killer cell mediated cytotoxicity);05200(Pathways in cancer);05320(Autoimmune thyroid disease);05152(Tuberculosis);05162(Measles);05164(Influenza A);05161(Hepatitis B);05160(Hepatitis C);05168(Herpes simplex infection);05167(Kaposi's sarcoma-associated herpesvirus infection);05165(Human papillomavirus infection)","K05414","NA","interferon alpha 21 [Source:HGNC Symbol;Acc:HGNC:5424]",{"v":0.050197,"d":"0.05"},0,"inf","inf",1,1,"up","no"]
["MSTRG.9222","SPC25","ENST00000479309;ENST00000282074","GO:0005634(nucleus);GO:0051301(cell division);GO:0005694(chromosome);GO:0005515(protein binding);GO:0007049(cell cycle);GO:0007059(chromosome segregation);GO:0000775(chromosome, centromeric region);GO:0000776(kinetochore);GO:0000777(condensed chromosome kinetochore);GO:0005829(cytosol);GO:0007052(mitotic spindle organization);GO:0007062(sister chromatid cohesion);GO:0031262(Ndc80 complex);GO:0031262(Ndc80 complex)","NA","NA","NA","SPC25, NDC80 kinetochore complex component [Source:HGNC Symbol;Acc:HGNC:24031]",{"v":0.227926008690929,"d":"0.23"},{"v":0.0247820858229223,"d":"0.02"},{"v":9.19720843191124,"d":"9.20"},{"v":3.20119603588939,"d":"3.20"},1,1,"up","no"]
["ENSG00000168955","TM4SF20","ENST00000304568","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005886(plasma membrane);GO:0005925(focal adhesion);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0045861(negative regulation of proteolysis)","NA","NA","NA","transmembrane 4 L six family member 20 [Source:HGNC Symbol;Acc:HGNC:26230]",{"v":0.0138726035545883,"d":"0.01"},{"v":0.0167973594486761,"d":"0.02"},{"v":0.825880019831431,"d":"0.83"},{"v":-0.275995886325947,"d":"-0.28"},1,1,"down","no"]
["MSTRG.9545","TMEM74B","ENST00000381894","GO:0016020(membrane);GO:0016021(integral component of membrane)","NA","NA","NA","transmembrane protein 74B [Source:HGNC Symbol;Acc:HGNC:15893]",{"v":0.0204249592760181,"d":"0.02"},{"v":0.0845547285067873,"d":"0.08"},{"v":0.241559042725547,"d":"0.24"},{"v":-2.04955223403989,"d":"-2.05"},1,1,"down","no"]
["ENSG00000173867","AC013489.1","ENST00000561140","NA","NA","NA","NA",null,{"v":0.19552,"d":"0.20"},0,"inf","inf",1,1,"up","no"]
["ENSG00000267606","AC006116.9","ENST00000591036","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000159173","TNNI1","ENST00000367312;ENST00000622580","GO:0046872(metal ion binding);GO:0003779(actin binding);GO:0005515(protein binding);GO:0005861(troponin complex);GO:0005829(cytosol);GO:0030049(muscle filament sliding);GO:0003009(skeletal muscle contraction);GO:0006942(regulation of striated muscle contraction);GO:0014883(transition between fast and slow fiber);GO:0055010(ventricular cardiac muscle tissue morphogenesis);GO:0060048(cardiac muscle contraction);GO:0060048(cardiac muscle contraction)","NA","NA","NA","troponin I1, slow skeletal type [Source:HGNC Symbol;Acc:HGNC:11945]",{"v":0.00683172514619883,"d":"0.01"},{"v":2.42529000531632E-3,"d":"0.00"},{"v":2.81686937695016,"d":"2.82"},{"v":1.49409266502789,"d":"1.49"},1,1,"up","no"]
["ENSG00000279071","AC073592.3","ENST00000625118","NA","NA","NA","NA",null,{"v":0.056055,"d":"0.06"},0,"inf","inf",1,1,"up","no"]
["ENSG00000137975","CLCA2","ENST00000370565","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0046872(metal ion binding);GO:0005634(nucleus);GO:0016787(hydrolase activity);GO:0007155(cell adhesion);GO:0006811(ion transport);GO:0005886(plasma membrane);GO:0030054(cell junction);GO:0008233(peptidase activity);GO:0006508(proteolysis);GO:0005576(extracellular region);GO:0008237(metallopeptidase activity);GO:1902476(chloride transmembrane transport);GO:0006821(chloride transport);GO:0034220(ion transmembrane transport);GO:0004222(metalloendopeptidase activity);GO:0005229(intracellular calcium activated chloride channel activity);GO:0005254(chloride channel activity);GO:0005887(integral component of plasma membrane);GO:0009925(basal plasma membrane);GO:0015276(ligand-gated ion channel activity)","04924(Renin secretion);04972(Pancreatic secretion)","K05028","NA","chloride channel accessory 2 [Source:HGNC Symbol;Acc:HGNC:2016]",{"v":0.0367308107206406,"d":"0.04"},{"v":0.00549140346975089,"d":"0.01"},{"v":6.6887838278448,"d":"6.69"},{"v":2.74174392012872,"d":"2.74"},1,1,"up","no"]
["ENSG00000164045","CDC25A","ENST00000302506","GO:0016787(hydrolase activity);GO:0005622(intracellular);GO:0051301(cell division);GO:0004725(protein tyrosine phosphatase activity);GO:0006470(protein dephosphorylation);GO:0035335(peptidyl-tyrosine dephosphorylation);GO:0004721(phosphoprotein phosphatase activity);GO:0005515(protein binding);GO:0007049(cell cycle);GO:1902751(positive regulation of cell cycle G2/M phase transition);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0019901(protein kinase binding);GO:0016579(protein deubiquitination);GO:0008283(cell proliferation);GO:0000086(G2/M transition of mitotic cell cycle);GO:0000082(G1/S transition of mitotic cell cycle);GO:0006260(DNA replication);GO:0051087(chaperone binding);GO:0009314(response to radiation);GO:0000079(regulation of cyclin-dependent protein serine/threonine kinase activity);GO:0051726(regulation of cell cycle);GO:0034644(cellular response to UV)","04110(Cell cycle);04218(Cellular senescence);04914(Progesterone-mediated oocyte maturation);05206(MicroRNAs in cancer)","K06645","EC:3.1.3.48","cell division cycle 25A [Source:HGNC Symbol;Acc:HGNC:1725]",{"v":0.170008038377459,"d":"0.17"},{"v":0.0744351423366529,"d":"0.07"},{"v":2.28397545891095,"d":"2.28"},{"v":1.19154714916937,"d":"1.19"},1,1,"up","no"]
["ENSG00000237770","SPATA31D2P","ENST00000429999","NA","NA","NA","NA","SPATA31 subfamily D member 2, pseudogene [Source:HGNC Symbol;Acc:HGNC:38607]",{"v":0.009786,"d":"0.01"},0,"inf","inf",1,1,"up","no"]
["ENSG00000232727","YWHAEP1","ENST00000453697","NA","NA","NA","NA","tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon pseudogene 1 [Source:HGNC Symbol;Acc:HGNC:49442]",0,0,1,0,1,1,"no","no"]
["ENSG00000141756","FKBP10","ENST00000321562;ENST00000489591;ENST00000487489","GO:0016853(isomerase activity);GO:0003755(peptidyl-prolyl cis-trans isomerase activity);GO:0000413(protein peptidyl-prolyl isomerization);GO:0046872(metal ion binding);GO:0005509(calcium ion binding);GO:0005783(endoplasmic reticulum);GO:0005528(FK506 binding);GO:0000412(histone peptidyl-prolyl isomerization);GO:0018208(peptidyl-proline modification);GO:0005730(nucleolus);GO:0061077(chaperone-mediated protein folding);GO:0005737(cytoplasm);GO:0005788(endoplasmic reticulum lumen);GO:0005788(endoplasmic reticulum lumen)","NA","NA","NA","FK506 binding protein 10 [Source:HGNC Symbol;Acc:HGNC:18169]",{"v":0.0856122447928856,"d":"0.09"},{"v":0.0494734036976363,"d":"0.05"},{"v":1.73047007875417,"d":"1.73"},{"v":0.791163996339436,"d":"0.79"},1,1,"up","no"]
["MSTRG.12182","VCAN-AS1","ENST00000512090","NA","NA","NA","NA","VCAN antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:40163]",{"v":0.080701,"d":"0.08"},{"v":0.403538,"d":"0.40"},{"v":0.199983644662956,"d":"0.20"},{"v":-2.32204607852981,"d":"-2.32"},1,1,"down","no"]
["ENSG00000226141","AC244107.1","ENST00000442033","NA","NA","NA","NA",null,{"v":0.039222,"d":"0.04"},0,"inf","inf",1,1,"up","no"]
["ENSG00000214870","AC004540.1","ENST00000449537;ENST00000439120;ENST00000421862","NA","NA","NA","NA",null,{"v":0.0595962602820212,"d":"0.06"},0,"inf","inf",1,1,"up","no"]
["MSTRG.9388","AC007879.3;AC007879.4","ENST00000417096;ENST00000448786;ENST00000440545","NA","NA","NA","NA",null,{"v":0.148184594573643,"d":"0.15"},{"v":0.0855949046511628,"d":"0.09"},{"v":1.73123149301423,"d":"1.73"},{"v":0.791798648733345,"d":"0.79"},1,1,"up","no"]
["ENSG00000280132","AC026471.6","ENST00000622954","NA","NA","NA","NA",null,0,{"v":0.023949,"d":"0.02"},"-inf","-inf",1,1,"down","no"]
["ENSG00000212722","KRTAP4-9","ENST00000391415","GO:0005882(intermediate filament);GO:0045095(keratin filament);GO:0005829(cytosol);GO:0031424(keratinization);GO:0007568(aging);GO:0042633(hair cycle)","NA","NA","NA","keratin associated protein 4-9 [Source:HGNC Symbol;Acc:HGNC:18910]",{"v":0.044427,"d":"0.04"},0,"inf","inf",1,1,"up","no"]
["ENSG00000214203","RPS4XP1","ENST00000482189","NA","NA","NA","NA","ribosomal protein S4X pseudogene 1 [Source:HGNC Symbol;Acc:HGNC:32444]",0,{"v":0.201356,"d":"0.20"},"-inf","-inf",1,1,"down","no"]
["ENSG00000226915","AC068137.1","ENST00000429272","NA","NA","NA","NA",null,{"v":0.088017,"d":"0.09"},0,"inf","inf",1,1,"up","no"]
["ENSG00000107130","NCS1","ENST00000372398","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0043231(intracellular membrane-bounded organelle);GO:0046872(metal ion binding);GO:0005509(calcium ion binding);GO:0005794(Golgi apparatus);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0048471(perinuclear region of cytoplasm);GO:0030054(cell junction);GO:0045202(synapse);GO:0045211(postsynaptic membrane);GO:0070588(calcium ion transmembrane transport);GO:0000287(magnesium ion binding);GO:0005245(voltage-gated calcium channel activity);GO:0019901(protein kinase binding);GO:0010975(regulation of neuron projection development);GO:0045921(positive regulation of exocytosis);GO:0048015(phosphatidylinositol-mediated signaling);GO:0005829(cytosol);GO:0030424(axon);GO:0030425(dendrite);GO:0031045(dense core granule);GO:0031410(cytoplasmic vesicle);GO:0070062(extracellular exosome);GO:0014069(postsynaptic density)","NA","NA","NA","neuronal calcium sensor 1 [Source:HGNC Symbol;Acc:HGNC:3953]",{"v":0.0737967806768765,"d":"0.07"},{"v":0.0737826258271885,"d":"0.07"},{"v":1.00019184529595,"d":"1.00"},{"v":0.000276747711564444,"d":"0.00"},1,1,"up","no"]
["ENSG00000151033","LYZL2","ENST00000375318","GO:0016787(hydrolase activity);GO:0008152(metabolic process);GO:0005576(extracellular region);GO:0016798(hydrolase activity, acting on glycosyl bonds);GO:0005615(extracellular space);GO:0003796(lysozyme activity);GO:0050829(defense response to Gram-negative bacterium);GO:0016998(cell wall macromolecule catabolic process);GO:0050830(defense response to Gram-positive bacterium)","NA","NA","NA","lysozyme like 2 [Source:HGNC Symbol;Acc:HGNC:29613]",{"v":0.061357,"d":"0.06"},{"v":0.148767,"d":"0.15"},{"v":0.412436897967963,"d":"0.41"},{"v":-1.27775468814121,"d":"-1.28"},1,1,"down","no"]
["ENSG00000260613","Z98885.2","ENST00000565177","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000253966","AC008514.2","ENST00000522096","NA","NA","NA","NA",null,{"v":0.038446,"d":"0.04"},0,"inf","inf",1,1,"up","no"]
["ENSG00000124882","EREG","ENST00000503689;ENST00000244869","GO:0005622(intracellular);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0018108(peptidyl-tyrosine phosphorylation);GO:0008083(growth factor activity);GO:0005886(plasma membrane);GO:0043547(positive regulation of GTPase activity);GO:0005576(extracellular region);GO:0007275(multicellular organism development);GO:0005615(extracellular space);GO:0030154(cell differentiation);GO:0046854(phosphatidylinositol phosphorylation);GO:0005887(integral component of plasma membrane);GO:0005515(protein binding);GO:0008285(negative regulation of cell proliferation);GO:0000165(MAPK cascade);GO:0001819(positive regulation of cytokine production);GO:0008284(positive regulation of cell proliferation);GO:0001550(ovarian cumulus expansion);GO:0045892(negative regulation of transcription, DNA-templated);GO:0046934(phosphatidylinositol-4,5-bisphosphate 3-kinase activity);GO:0014066(regulation of phosphatidylinositol 3-kinase signaling);GO:0038111(interleukin-7-mediated signaling pathway);GO:0048015(phosphatidylinositol-mediated signaling);GO:0009653(anatomical structure morphogenesis);GO:0007173(epidermal growth factor receptor signaling pathway);GO:0005088(Ras guanyl-nucleotide exchange factor activity);GO:0001525(angiogenesis);GO:0004713(protein tyrosine kinase activity);GO:0038128(ERBB2 signaling pathway);GO:1901185(negative regulation of ERBB signaling pathway);GO:2000145(regulation of cell motility);GO:0007267(cell-cell signaling);GO:0051781(positive regulation of cell division);GO:0045089(positive regulation of innate immune response);GO:0005154(epidermal growth factor receptor binding);GO:0001556(oocyte maturation);GO:0007143(female meiotic nuclear division);GO:0009299(mRNA transcription);GO:0009887(animal organ morphogenesis);GO:0019221(cytokine-mediated signaling pathway);GO:0030216(keratinocyte differentiation);GO:0030728(ovulation);GO:0042060(wound healing);GO:0042108(positive regulation of cytokine biosynthetic process);GO:0042327(positive regulation of phosphorylation);GO:0042700(luteinizing hormone signaling pathway);GO:0043434(response to peptide hormone);GO:0043616(keratinocyte proliferation);GO:0045410(positive regulation of interleukin-6 biosynthetic process);GO:0045740(positive regulation of DNA replication);GO:0045741(positive regulation of epidermal growth factor-activated receptor activity);GO:0045840(positive regulation of mitotic nuclear division);GO:0045860(positive regulation of protein kinase activity);GO:0048146(positive regulation of fibroblast proliferation);GO:0048160(primary follicle stage);GO:0048661(positive regulation of smooth muscle cell proliferation);GO:0050680(negative regulation of epithelial cell proliferation);GO:0051151(negative regulation of smooth muscle cell differentiation);GO:0051151(negative regulation of smooth muscle cell differentiation)","04012(ErbB signaling pathway);04012(ErbB signaling pathway)","K09784","NA","epiregulin [Source:HGNC Symbol;Acc:HGNC:3443]",{"v":0.0255050886828756,"d":"0.03"},{"v":0.0134073022564282,"d":"0.01"},{"v":1.90232816379202,"d":"1.90"},{"v":0.927766141801658,"d":"0.93"},1,1,"up","no"]
["MSTRG.6352","AC004771.5","ENST00000575985","NA","NA","NA","NA",null,{"v":0.035826,"d":"0.04"},{"v":0.090857,"d":"0.09"},{"v":0.394311940742045,"d":"0.39"},{"v":-1.34259069540158,"d":"-1.34"},1,1,"down","no"]
["ENSG00000229921","KIF25-AS1","ENST00000456585","NA","NA","NA","NA","KIF25 antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:20953]",0,{"v":0.0147742179404145,"d":"0.01"},"-inf","-inf",1,1,"down","no"]
["ENSG00000250195","AC109927.1","ENST00000511951","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000213598","AL049873.1","ENST00000480540","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["MSTRG.6220","AC010531.3","ENST00000569147","NA","NA","NA","NA",null,{"v":0.041204,"d":"0.04"},{"v":0.090675,"d":"0.09"},{"v":0.4544141163496,"d":"0.45"},{"v":-1.13792044210632,"d":"-1.14"},1,1,"down","no"]
["ENSG00000223797","ENTPD3-AS1","ENST00000425156;ENST00000439293;ENST00000420850;ENST00000452768","NA","NA","NA","NA","ENTPD3 antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:26710]",{"v":0.144547793988517,"d":"0.14"},{"v":0.0272214478216819,"d":"0.03"},{"v":5.31007002035302,"d":"5.31"},{"v":2.40873088501249,"d":"2.41"},1,1,"up","no"]
["ENSG00000236417","CTSLP1","ENST00000457530","NA","NA","NA","NA","cathepsin L pseudogene 1 [Source:HGNC Symbol;Acc:HGNC:2539]",0,{"v":0.038567,"d":"0.04"},"-inf","-inf",1,1,"down","no"]
["ENSG00000147573","TRIM55","ENST00000315962;ENST00000517647","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0005622(intracellular);GO:0004871(signal transducer activity);GO:0007165(signal transduction);GO:0005874(microtubule);GO:0042802(identical protein binding);GO:0005515(protein binding);GO:0005515(protein binding)","NA","NA","NA","tripartite motif containing 55 [Source:HGNC Symbol;Acc:HGNC:14215]",0,{"v":0.0148083407984421,"d":"0.01"},"-inf","-inf",1,1,"down","no"]
["ENSG00000026559","KCNG1","ENST00000424171;ENST00000439216;ENST00000371571;ENST00000506387","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0055085(transmembrane transport);GO:0005216(ion channel activity);GO:0006811(ion transport);GO:0005244(voltage-gated ion channel activity);GO:0005249(voltage-gated potassium channel activity);GO:0005267(potassium channel activity);GO:0006813(potassium ion transport);GO:0034765(regulation of ion transmembrane transport);GO:0051260(protein homooligomerization);GO:0071805(potassium ion transmembrane transport);GO:0008076(voltage-gated potassium channel complex);GO:0005886(plasma membrane);GO:0005251(delayed rectifier potassium channel activity);GO:1902259(regulation of delayed rectifier potassium channel activity);GO:1902259(regulation of delayed rectifier potassium channel activity)","NA","NA","NA","potassium voltage-gated channel modifier subfamily G member 1 [Source:HGNC Symbol;Acc:HGNC:6248]",{"v":0.0769249275335663,"d":"0.08"},{"v":0.156526806878793,"d":"0.16"},{"v":0.491448903018467,"d":"0.49"},{"v":-1.02488667057787,"d":"-1.02"},1,1,"down","no"]
["ENSG00000230204","FTH1P5","ENST00000425761","NA","NA","NA","NA","ferritin heavy chain 1 pseudogene 5 [Source:HGNC Symbol;Acc:HGNC:3996]",{"v":0.455387,"d":"0.46"},{"v":1.422827,"d":"1.42"},{"v":0.32005788476041,"d":"0.32"},{"v":-1.64359524444774,"d":"-1.64"},1,1,"down","no"]
["ENSG00000247877","AC021086.1","ENST00000499025;ENST00000504833","NA","NA","NA","NA",null,0,{"v":0.0260126094570928,"d":"0.03"},"-inf","-inf",1,1,"down","no"]
["ENSG00000182329","KIAA2012","ENST00000469462;ENST00000498697","NA","NA","NA","NA","KIAA2012 [Source:HGNC Symbol;Acc:HGNC:51250]",{"v":0.00140221767594108,"d":"0.00"},{"v":0.0157523620798187,"d":"0.02"},{"v":0.0890163436337935,"d":"0.09"},{"v":-3.48978594678873,"d":"-3.49"},1,1,"down","no"]
["ENSG00000233421","LINC01783","ENST00000614408;ENST00000415386","NA","NA","NA","NA","long intergenic non-protein coding RNA 1783 [Source:HGNC Symbol;Acc:HGNC:52573]",{"v":0.0248200560115886,"d":"0.02"},{"v":0.0201576359246741,"d":"0.02"},{"v":1.23129796094826,"d":"1.23"},{"v":0.300179920852957,"d":"0.30"},1,1,"up","no"]
["ENSG00000151962","RBM46","ENST00000514866","GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0001829(trophectodermal cell differentiation);GO:0048255(mRNA stabilization);GO:0005634(nucleus)","NA","NA","NA","RNA binding motif protein 46 [Source:HGNC Symbol;Acc:HGNC:28401]",0,{"v":0.00427530543829153,"d":"0.00"},"-inf","-inf",1,1,"down","no"]
["MSTRG.464","AL031289.1","ENST00000440100","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000261097","LINC00563","ENST00000566370","NA","NA","NA","NA","long intergenic non-protein coding RNA 563 [Source:HGNC Symbol;Acc:HGNC:43707]",{"v":0.110147,"d":"0.11"},{"v":0.221276,"d":"0.22"},{"v":0.497781051718216,"d":"0.50"},{"v":-1.00641678042307,"d":"-1.01"},1,1,"down","no"]
["MSTRG.4544","AL049780.3","ENST00000624612","NA","NA","NA","NA",null,{"v":0.081611,"d":"0.08"},{"v":0.028821,"d":"0.03"},{"v":2.83165053259776,"d":"2.83"},{"v":1.50164322657974,"d":"1.50"},1,1,"up","no"]
["ENSG00000224533","TMLHE-AS1","ENST00000433624","NA","NA","NA","NA","TMLHE antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:44261]",{"v":0.320064559349593,"d":"0.32"},{"v":0.572821245528455,"d":"0.57"},{"v":0.558751201789518,"d":"0.56"},{"v":-0.839722065568743,"d":"-0.84"},1,1,"down","no"]
["MSTRG.6741","AC244093.3","ENST00000615419","NA","NA","NA","NA",null,{"v":0.236347,"d":"0.24"},0,"inf","inf",1,1,"up","no"]
["MSTRG.5994","TK2","ENST00000565729","GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0006139(nucleobase-containing compound metabolic process);GO:0005739(mitochondrion);GO:0019206(nucleoside kinase activity);GO:0009165(nucleotide biosynthetic process);GO:0005759(mitochondrial matrix);GO:0009157(deoxyribonucleoside monophosphate biosynthetic process);GO:0004797(thymidine kinase activity);GO:0071897(DNA biosynthetic process);GO:0043097(pyrimidine nucleoside salvage);GO:0004137(deoxycytidine kinase activity);GO:0046092(deoxycytidine metabolic process);GO:0046104(thymidine metabolic process)","00240(Pyrimidine metabolism);00983(Drug metabolism - other enzymes)","NA","NA","thymidine kinase 2, mitochondrial [Source:HGNC Symbol;Acc:HGNC:11831]",0,0,1,0,1,1,"no","no"]
["ENSG00000159307","SCUBE1","ENST00000360835","GO:0016020(membrane);GO:0005509(calcium ion binding);GO:0005886(plasma membrane);GO:0005576(extracellular region);GO:0006954(inflammatory response);GO:0007165(signal transduction);GO:0030154(cell differentiation);GO:0009986(cell surface);GO:0007596(blood coagulation);GO:0046982(protein heterodimerization activity);GO:0022617(extracellular matrix disassembly);GO:0045446(endothelial cell differentiation);GO:0042802(identical protein binding);GO:0005615(extracellular space);GO:0051260(protein homooligomerization);GO:0009897(external side of plasma membrane);GO:0009791(post-embryonic development);GO:0007512(adult heart development);GO:0045880(positive regulation of smoothened signaling pathway);GO:0019897(extrinsic component of plasma membrane)","NA","NA","NA","signal peptide, CUB domain and EGF like domain containing 1 [Source:HGNC Symbol;Acc:HGNC:13441]",{"v":0.0134466992995468,"d":"0.01"},{"v":0.00440733613514627,"d":"0.00"},{"v":3.05098111131488,"d":"3.05"},{"v":1.60927324819035,"d":"1.61"},1,1,"up","no"]
["ENSG00000140067","FAM181A","ENST00000267594","NA","NA","NA","NA","family with sequence similarity 181 member A [Source:HGNC Symbol;Acc:HGNC:20491]",0,{"v":0.0167134677565849,"d":"0.02"},"-inf","-inf",1,1,"down","no"]
["ENSG00000229487","ALG13-AS1","ENST00000430794","NA","NA","NA","NA","ALG13 antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:41277]",{"v":0.114603,"d":"0.11"},{"v":0.060606,"d":"0.06"},{"v":1.89095139095139,"d":"1.89"},{"v":0.919112277653236,"d":"0.92"},1,1,"up","no"]
["ENSG00000257302","FAHD2P1","ENST00000546381","NA","NA","NA","NA","fumarylacetoacetate hydrolase domain containing 2 pseudogene 1 [Source:HGNC Symbol;Acc:HGNC:32441]",0,{"v":0.040166,"d":"0.04"},"-inf","-inf",1,1,"down","no"]
["ENSG00000204065","TCEAL5","ENST00000372680","GO:0005634(nucleus);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0005515(protein binding);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0050699(WW domain binding)","NA","NA","NA","transcription elongation factor A like 5 [Source:HGNC Symbol;Acc:HGNC:22282]",{"v":0.093445,"d":"0.09"},{"v":0.038931,"d":"0.04"},{"v":2.40027227659192,"d":"2.40"},{"v":1.26319806825405,"d":"1.26"},1,1,"up","no"]
["ENSG00000258057","BCDIN3D-AS1","ENST00000548872","NA","NA","NA","NA","BCDIN3D antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:44113]",{"v":0.0848801846068043,"d":"0.08"},{"v":0.00359557780256553,"d":"0.00"},{"v":23.6068274051086,"d":"23.61"},{"v":4.56113226121177,"d":"4.56"},1,1,"up","no"]
["ENSG00000158246","FAM46B","ENST00000289166","GO:0005515(protein binding)","NA","NA","NA","family with sequence similarity 46 member B [Source:HGNC Symbol;Acc:HGNC:28273]",{"v":0.084585,"d":"0.08"},{"v":0.108922,"d":"0.11"},{"v":0.776564881291199,"d":"0.78"},{"v":-0.364821629377568,"d":"-0.36"},1,1,"down","no"]
["ENSG00000259940","AC109449.1","ENST00000567108","NA","NA","NA","NA",null,0,{"v":0.155507,"d":"0.16"},"-inf","-inf",1,1,"down","no"]
["ENSG00000111432","FZD10","ENST00000229030;ENST00000539839","GO:0005737(cytoplasm);GO:0043507(positive regulation of JUN kinase activity);GO:0034260(negative regulation of GTPase activity);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005654(nucleoplasm);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0004871(signal transducer activity);GO:0007165(signal transduction);GO:0004888(transmembrane signaling receptor activity);GO:0004930(G-protein coupled receptor activity);GO:0007166(cell surface receptor signaling pathway);GO:0007186(G-protein coupled receptor signaling pathway);GO:0007275(multicellular organism development);GO:0016055(Wnt signaling pathway);GO:0042813(Wnt-activated receptor activity);GO:0005887(integral component of plasma membrane);GO:0060070(canonical Wnt signaling pathway);GO:0009986(cell surface);GO:0043547(positive regulation of GTPase activity);GO:0030182(neuron differentiation);GO:0071300(cellular response to retinoic acid);GO:0017147(Wnt-protein binding);GO:0038031(non-canonical Wnt signaling pathway via JNK cascade);GO:0032956(regulation of actin cytoskeleton organization);GO:0032956(regulation of actin cytoskeleton organization)","04310(Wnt signaling pathway);04390(Hippo signaling pathway);04150(mTOR signaling pathway);04550(Signaling pathways regulating pluripotency of stem cells);04916(Melanogenesis);05200(Pathways in cancer);05205(Proteoglycans in cancer);05225(Hepatocellular carcinoma);05226(Gastric cancer);05217(Basal cell carcinoma);05224(Breast cancer);05166(HTLV-I infection);05165(Human papillomavirus infection);05165(Human papillomavirus infection)","K02842","NA","frizzled class receptor 10 [Source:HGNC Symbol;Acc:HGNC:4039]",{"v":0.0464639192565509,"d":"0.05"},{"v":0.0270148829981718,"d":"0.03"},{"v":1.71993783055419,"d":"1.72"},{"v":0.78235641773426,"d":"0.78"},1,1,"up","no"]
["ENSG00000223704","LINC01422","ENST00000434868","NA","NA","NA","NA","long intergenic non-protein coding RNA 1422 [Source:HGNC Symbol;Acc:HGNC:50728]",{"v":0.056168,"d":"0.06"},{"v":0.044494,"d":"0.04"},{"v":1.262372454713,"d":"1.26"},{"v":0.336137630835903,"d":"0.34"},1,1,"up","no"]
["MSTRG.10574","PRR34","ENST00000396008","NA","NA","NA","NA","proline rich 34 [Source:HGNC Symbol;Acc:HGNC:25606]",{"v":0.001581,"d":"0.00"},{"v":0.079684,"d":"0.08"},{"v":0.0198408714421967,"d":"0.02"},{"v":-5.65538079722909,"d":"-5.66"},1,1,"down","no"]
["MSTRG.5985","AC009118.3","ENST00000622896","NA","NA","NA","NA",null,{"v":0.229827,"d":"0.23"},{"v":0.051042,"d":"0.05"},{"v":4.50270365581286,"d":"4.50"},{"v":2.17079153023186,"d":"2.17"},1,1,"up","no"]
["ENSG00000258806","OR11H7","ENST00000553765","NA","NA","NA","NA","olfactory receptor family 11 subfamily H member 7 (gene/pseudogene) [Source:HGNC Symbol;Acc:HGNC:15350]",{"v":0.054394,"d":"0.05"},0,"inf","inf",1,1,"up","no"]
["ENSG00000243543","WFDC6","ENST00000372670","GO:0005576(extracellular region);GO:0004867(serine-type endopeptidase inhibitor activity);GO:0010951(negative regulation of endopeptidase activity);GO:0030414(peptidase inhibitor activity);GO:0010466(negative regulation of peptidase activity)","NA","NA","NA","WAP four-disulfide core domain 6 [Source:HGNC Symbol;Acc:HGNC:16164]",{"v":0.0915455050505051,"d":"0.09"},0,"inf","inf",1,1,"up","no"]
["ENSG00000277925","Telomerase-vert","ENST00000363312","NA","05200(Pathways in cancer);05225(Hepatocellular carcinoma);05226(Gastric cancer)","K22183","NA","Vertebrate telomerase RNA [Source:RFAM;Acc:RF00024]",{"v":0.102491,"d":"0.10"},0,"inf","inf",1,1,"up","no"]
["ENSG00000216966","AL353747.1","ENST00000404577","NA","NA","NA","NA",null,{"v":0.096259,"d":"0.10"},0,"inf","inf",1,1,"up","no"]
["ENSG00000198691","ABCA4","ENST00000370225","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005215(transporter activity);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0005887(integral component of plasma membrane);GO:0007601(visual perception);GO:0042626(ATPase activity, coupled to transmembrane movement of substances);GO:0016887(ATPase activity);GO:0050896(response to stimulus);GO:0055085(transmembrane transport);GO:0001523(retinoid metabolic process);GO:0043231(intracellular membrane-bounded organelle);GO:0097381(photoreceptor disc membrane);GO:0045332(phospholipid translocation);GO:0007603(phototransduction, visible light);GO:0090555(phosphatidylethanolamine-translocating ATPase activity);GO:0004012(phospholipid-translocating ATPase activity);GO:0005395(eye pigment precursor transporter activity);GO:0005548(phospholipid transporter activity);GO:0006649(phospholipid transfer to membrane);GO:0045494(photoreceptor cell maintenance);GO:0001750(photoreceptor outer segment)","02010(ABC transporters)","K05644","NA","ATP binding cassette subfamily A member 4 [Source:HGNC Symbol;Acc:HGNC:34]",{"v":0.0395404333617852,"d":"0.04"},{"v":0.0266469687842946,"d":"0.03"},{"v":1.483862336533,"d":"1.48"},{"v":0.569357253944159,"d":"0.57"},1,1,"up","no"]
["ENSG00000232883","AL451081.2","ENST00000448115","NA","NA","NA","NA",null,{"v":0.110187,"d":"0.11"},0,"inf","inf",1,1,"up","no"]
["ENSG00000170099","SERPINA6","ENST00000555056;ENST00000557225","GO:0005615(extracellular space);GO:0006810(transport);GO:0010951(negative regulation of endopeptidase activity);GO:0005576(extracellular region);GO:0008289(lipid binding);GO:0070062(extracellular exosome);GO:0005496(steroid binding);GO:0004867(serine-type endopeptidase inhibitor activity);GO:0008211(glucocorticoid metabolic process);GO:0008211(glucocorticoid metabolic process)","NA","NA","NA","serpin family A member 6 [Source:HGNC Symbol;Acc:HGNC:1540]",{"v":0.0456766603671706,"d":"0.05"},{"v":0.0372517316414687,"d":"0.04"},{"v":1.22616206963982,"d":"1.23"},{"v":0.294149681812078,"d":"0.29"},1,1,"up","no"]
["ENSG00000135577","NMBR","ENST00000258042","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0004930(G-protein coupled receptor activity);GO:0007186(G-protein coupled receptor signaling pathway);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0004871(signal transducer activity);GO:0007165(signal transduction);GO:0005887(integral component of plasma membrane);GO:0007200(phospholipase C-activating G-protein coupled receptor signaling pathway);GO:0004946(bombesin receptor activity);GO:0008528(G-protein coupled peptide receptor activity);GO:0031989(bombesin receptor signaling pathway)","04080(Neuroactive ligand-receptor interaction)","K04168","NA","neuromedin B receptor [Source:HGNC Symbol;Acc:HGNC:7843]",0,{"v":0.0537493324873096,"d":"0.05"},"-inf","-inf",1,1,"down","no"]
["ENSG00000163817","SLC6A20","ENST00000358525","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005887(integral component of plasma membrane);GO:0015293(symporter activity);GO:0055085(transmembrane transport);GO:0005886(plasma membrane);GO:0003333(amino acid transmembrane transport);GO:0005515(protein binding);GO:0005328(neurotransmitter:sodium symporter activity);GO:0006836(neurotransmitter transport);GO:0006865(amino acid transport);GO:0016324(apical plasma membrane);GO:0015171(amino acid transmembrane transporter activity);GO:0015824(proline transport);GO:0015816(glycine transport)","NA","NA","NA","solute carrier family 6 member 20 [Source:HGNC Symbol;Acc:HGNC:30927]",{"v":0.0434443370921666,"d":"0.04"},{"v":0.0249453107803338,"d":"0.02"},{"v":1.74158331699026,"d":"1.74"},{"v":0.80039949281176,"d":"0.80"},1,1,"up","no"]
["MSTRG.3679","AC007622.2","ENST00000546714","NA","NA","NA","NA",null,{"v":0.125196266044341,"d":"0.13"},{"v":0.145585624270712,"d":"0.15"},{"v":0.859949371179275,"d":"0.86"},{"v":-0.217676370071099,"d":"-0.22"},1,1,"down","no"]
["ENSG00000203963","C1orf141","ENST00000371004;ENST00000475209","NA","NA","NA","NA","chromosome 1 open reading frame 141 [Source:HGNC Symbol;Acc:HGNC:32044]",0,{"v":5.8350473914775E-3,"d":"0.01"},"-inf","-inf",1,1,"down","no"]
["MSTRG.805","WNT2B","ENST00000478360;ENST00000369686","GO:0005102(receptor binding);GO:0005576(extracellular region);GO:0007275(multicellular organism development);GO:0016055(Wnt signaling pathway);GO:0005578(proteinaceous extracellular matrix);GO:0043231(intracellular membrane-bounded organelle);GO:0005615(extracellular space);GO:0008584(male gonad development);GO:0030182(neuron differentiation);GO:0090263(positive regulation of canonical Wnt signaling pathway);GO:0002062(chondrocyte differentiation);GO:0005109(frizzled binding);GO:0045165(cell fate commitment);GO:0071425(hematopoietic stem cell proliferation);GO:0061072(iris morphogenesis);GO:0061303(cornea development in camera-type eye);GO:0002088(lens development in camera-type eye);GO:0021871(forebrain regionalization);GO:0009267(cellular response to starvation);GO:0060070(canonical Wnt signaling pathway);GO:0060492(lung induction);GO:0060638(mesenchymal-epithelial cell signaling);GO:0090190(positive regulation of branching involved in ureteric bud morphogenesis);GO:0090190(positive regulation of branching involved in ureteric bud morphogenesis)","04310(Wnt signaling pathway);04390(Hippo signaling pathway);04150(mTOR signaling pathway);04550(Signaling pathways regulating pluripotency of stem cells);04916(Melanogenesis);05200(Pathways in cancer);05205(Proteoglycans in cancer);05225(Hepatocellular carcinoma);05226(Gastric cancer);05217(Basal cell carcinoma);05224(Breast cancer);05166(HTLV-I infection);05165(Human papillomavirus infection);05165(Human papillomavirus infection)","K00182","NA","Wnt family member 2B [Source:HGNC Symbol;Acc:HGNC:12781]",{"v":0.183616144813311,"d":"0.18"},{"v":0.0299148682429743,"d":"0.03"},{"v":6.13795599305153,"d":"6.14"},{"v":2.61775830223419,"d":"2.62"},1,1,"up","no"]
["ENSG00000196263","ZNF471","ENST00000593197;ENST00000308031","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0005622(intracellular);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding)","NA","NA","NA","zinc finger protein 471 [Source:HGNC Symbol;Acc:HGNC:23226]",{"v":0.0302115236620964,"d":"0.03"},{"v":0.0060370701754386,"d":"0.01"},{"v":5.00433534548097,"d":"5.00"},{"v":2.3231784691704,"d":"2.32"},1,1,"up","no"]
["ENSG00000132631","SCP2D1","ENST00000377428","GO:0015248(sterol transporter activity);GO:0006694(steroid biosynthetic process);GO:0015914(phospholipid transport);GO:0032934(sterol binding);GO:0030301(cholesterol transport)","NA","NA","NA","SCP2 sterol binding domain containing 1 [Source:HGNC Symbol;Acc:HGNC:16211]",0,{"v":0.055633,"d":"0.06"},"-inf","-inf",1,1,"down","no"]
["ENSG00000235631","RNF148","ENST00000434824","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0046872(metal ion binding)","NA","NA","NA","ring finger protein 148 [Source:HGNC Symbol;Acc:HGNC:22411]",{"v":0.033374,"d":"0.03"},0,"inf","inf",1,1,"up","no"]
["ENSG00000120149","MSX2","ENST00000239243","GO:0005634(nucleus);GO:0016607(nuclear speck);GO:0005829(cytosol);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0043565(sequence-specific DNA binding);GO:0007275(multicellular organism development);GO:0005515(protein binding);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0001503(ossification);GO:0044212(transcription regulatory region DNA binding);GO:0045892(negative regulation of transcription, DNA-templated);GO:0001649(osteoblast differentiation);GO:0003712(transcription cofactor activity);GO:2000678(negative regulation of transcription regulatory region DNA binding);GO:0000977(RNA polymerase II regulatory region sequence-specific DNA binding);GO:0000989(transcription factor activity, transcription factor binding);GO:0001227(transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding);GO:0008134(transcription factor binding);GO:0002063(chondrocyte development);GO:0002076(osteoblast development);GO:0003148(outflow tract septum morphogenesis);GO:0003151(outflow tract morphogenesis);GO:0003198(epithelial to mesenchymal transition involved in endocardial cushion formation);GO:0003416(endochondral bone growth);GO:0008285(negative regulation of cell proliferation);GO:0009952(anterior/posterior pattern specification);GO:0023019(signal transduction involved in regulation of gene expression);GO:0030326(embryonic limb morphogenesis);GO:0030509(BMP signaling pathway);GO:0030513(positive regulation of BMP signaling pathway);GO:0032792(negative regulation of CREB transcription factor activity);GO:0035115(embryonic forelimb morphogenesis);GO:0035116(embryonic hindlimb morphogenesis);GO:0035313(wound healing, spreading of epidermal cells);GO:0035880(embryonic nail plate morphogenesis);GO:0042060(wound healing);GO:0042476(odontogenesis);GO:0042733(embryonic digit morphogenesis);GO:0042981(regulation of apoptotic process);GO:0043066(negative regulation of apoptotic process);GO:0045599(negative regulation of fat cell differentiation);GO:0045617(negative regulation of keratinocyte differentiation);GO:0045669(positive regulation of osteoblast differentiation);GO:0048863(stem cell differentiation);GO:0051216(cartilage development);GO:0051795(positive regulation of timing of catagen);GO:0060346(bone trabecula formation);GO:0060349(bone morphogenesis);GO:0060363(cranial suture morphogenesis);GO:0060364(frontal suture morphogenesis);GO:0060444(branching involved in mammary gland duct morphogenesis);GO:0061180(mammary gland epithelium development);GO:0061312(BMP signaling pathway involved in heart development);GO:0070166(enamel mineralization);GO:0071363(cellular response to growth factor stimulus);GO:0071392(cellular response to estradiol stimulus);GO:0090427(activation of meiosis);GO:2001055(positive regulation of mesenchymal cell apoptotic process)","05166(HTLV-I infection)","K09341","NA","msh homeobox 2 [Source:HGNC Symbol;Acc:HGNC:7392]",{"v":0.022643972246696,"d":"0.02"},0,"inf","inf",1,1,"up","no"]
["ENSG00000114993","RTKN","ENST00000305557;ENST00000640304;ENST00000472518;ENST00000272430;ENST00000492013;ENST00000484453","GO:0000166(nucleotide binding);GO:0007165(signal transduction);GO:0005525(GTP binding);GO:0005515(protein binding);GO:0006915(apoptotic process);GO:0007266(Rho protein signal transduction);GO:0017049(GTP-Rho binding);GO:0005575(cellular_component);GO:0005829(cytosol);GO:0042981(regulation of apoptotic process);GO:0034260(negative regulation of GTPase activity);GO:0005095(GTPase inhibitor activity);GO:0032185(septin cytoskeleton organization);GO:0017048(Rho GTPase binding);GO:0017048(Rho GTPase binding)","NA","NA","NA","rhotekin [Source:HGNC Symbol;Acc:HGNC:10466]",{"v":0.18591374238921,"d":"0.19"},{"v":0.11619763699422,"d":"0.12"},{"v":1.59997868457908,"d":"1.60"},{"v":0.678052685202081,"d":"0.68"},1,1,"up","no"]
["ENSG00000213714","FAM209B","ENST00000371325","GO:0005634(nucleus);GO:0016020(membrane);GO:0016021(integral component of membrane)","NA","NA","NA","family with sequence similarity 209 member B [Source:HGNC Symbol;Acc:HGNC:16101]",{"v":0.067154,"d":"0.07"},{"v":0.394443,"d":"0.39"},{"v":0.170250200916229,"d":"0.17"},{"v":-2.55427159409098,"d":"-2.55"},1,1,"down","no"]
["MSTRG.5084","AC090971.2","ENST00000558142","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["MSTRG.13083","AL035701.1","ENST00000437249;ENST00000444038","NA","NA","NA","NA",null,{"v":0.423288958051421,"d":"0.42"},{"v":0.130224608930988,"d":"0.13"},{"v":3.25045290230621,"d":"3.25"},{"v":1.70064075026056,"d":"1.70"},1,1,"up","no"]
["ENSG00000237603","HMGB3P12","ENST00000438745","NA","NA","NA","NA","high mobility group box 3 pseudogene 12 [Source:HGNC Symbol;Acc:HGNC:39304]",{"v":0.274576,"d":"0.27"},0,"inf","inf",1,1,"up","no"]
["ENSG00000135119","RNFT2","ENST00000319176;ENST00000551251;ENST00000257575;ENST00000392549","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0046872(metal ion binding);GO:0046872(metal ion binding)","NA","NA","NA","ring finger protein, transmembrane 2 [Source:HGNC Symbol;Acc:HGNC:25905]",{"v":0.207823194697086,"d":"0.21"},{"v":0.0632745040850933,"d":"0.06"},{"v":3.28446975131721,"d":"3.28"},{"v":1.71566047895187,"d":"1.72"},1,1,"up","no"]
["ENSG00000179044","EXOC3L1","ENST00000314586;ENST00000563536;ENST00000545725;ENST00000564324","GO:0006887(exocytosis);GO:0000145(exocyst);GO:0031410(cytoplasmic vesicle);GO:0030072(peptide hormone secretion);GO:0030141(secretory granule);GO:0003674(molecular_function);GO:0000149(SNARE binding);GO:0030133(transport vesicle);GO:0051601(exocyst localization);GO:0051601(exocyst localization)","NA","NA","NA","exocyst complex component 3 like 1 [Source:HGNC Symbol;Acc:HGNC:27540]",{"v":0.144076610334742,"d":"0.14"},{"v":0.0855881751706207,"d":"0.09"},{"v":1.68337051289532,"d":"1.68"},{"v":0.751352751407048,"d":"0.75"},1,1,"up","no"]
["ENSG00000093100","AC016026.1","ENST00000476405","NA","NA","NA","NA",null,{"v":0.525392,"d":"0.53"},0,"inf","inf",1,1,"up","no"]
["ENSG00000230054","AL160275.1","ENST00000423632","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["MSTRG.3576","PPP1R12A-AS1","ENST00000552885","NA","NA","NA","NA","PPP1R12A antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:51903]",{"v":0.095577,"d":"0.10"},{"v":0.038231,"d":"0.04"},{"v":2.49998692160812,"d":"2.50"},{"v":1.32192054761518,"d":"1.32"},1,1,"up","no"]
["ENSG00000282840","AC004554.2","ENST00000634846","NA","NA","NA","NA",null,{"v":0.027154,"d":"0.03"},{"v":0.017514,"d":"0.02"},{"v":1.55041680940962,"d":"1.55"},{"v":0.632656117455176,"d":"0.63"},1,1,"up","no"]
["ENSG00000163827","LRRC2","ENST00000395905","NA","NA","NA","NA","leucine rich repeat containing 2 [Source:HGNC Symbol;Acc:HGNC:14676]",{"v":0.0170063500533618,"d":"0.02"},{"v":0.0558332977588047,"d":"0.06"},{"v":0.304591538311562,"d":"0.30"},{"v":-1.71505223121551,"d":"-1.72"},1,1,"down","no"]
["ENSG00000197446","CYP2F1","ENST00000531409;ENST00000331105","GO:0055114(oxidation-reduction process);GO:0005506(iron ion binding);GO:0016705(oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen);GO:0020037(heme binding);GO:0016020(membrane);GO:0046872(metal ion binding);GO:0004497(monooxygenase activity);GO:0016491(oxidoreductase activity);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0008392(arachidonic acid epoxygenase activity);GO:0008395(steroid hydroxylase activity);GO:0019373(epoxygenase P450 pathway);GO:0070330(aromatase activity);GO:0019825(oxygen binding);GO:0043231(intracellular membrane-bounded organelle);GO:0006805(xenobiotic metabolic process);GO:0031090(organelle membrane);GO:0016712(oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen);GO:0018931(naphthalene metabolic process);GO:0009636(response to toxic substance);GO:0018979(trichloroethylene metabolic process);GO:0018979(trichloroethylene metabolic process)","00980(Metabolism of xenobiotics by cytochrome P450);00980(Metabolism of xenobiotics by cytochrome P450)","K07416","EC:1.14.14.1","cytochrome P450 family 2 subfamily F member 1 [Source:HGNC Symbol;Acc:HGNC:2632]",{"v":0.128486279225117,"d":"0.13"},{"v":0.0213336406145625,"d":"0.02"},{"v":6.02270758875592,"d":"6.02"},{"v":2.59041221567127,"d":"2.59"},1,1,"up","no"]
["ENSG00000180919","OR56B4","ENST00000316529","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0007186(G-protein coupled receptor signaling pathway);GO:0005886(plasma membrane);GO:0004871(signal transducer activity);GO:0007165(signal transduction);GO:0004930(G-protein coupled receptor activity);GO:0004984(olfactory receptor activity);GO:0007608(sensory perception of smell);GO:0050896(response to stimulus);GO:0050911(detection of chemical stimulus involved in sensory perception of smell)","04740(Olfactory transduction)","K04257","NA","olfactory receptor family 56 subfamily B member 4 [Source:HGNC Symbol;Acc:HGNC:15248]",0,{"v":0.223367,"d":"0.22"},"-inf","-inf",1,1,"down","no"]
["ENSG00000215784","FAM72D","ENST00000400889","GO:0043231(intracellular membrane-bounded organelle);GO:0005829(cytosol)","NA","NA","NA","family with sequence similarity 72 member D [Source:HGNC Symbol;Acc:HGNC:33593]",{"v":0.117211,"d":"0.12"},{"v":0.120913,"d":"0.12"},{"v":0.969382944761936,"d":"0.97"},{"v":-0.0448613948091151,"d":"-0.04"},1,1,"down","no"]
["ENSG00000268062","AL031274.2","ENST00000599419","NA","NA","NA","NA",null,0,{"v":0.449496,"d":"0.45"},"-inf","-inf",1,1,"down","no"]
["ENSG00000234801","MORF4","ENST00000447135","NA","NA","NA","NA","mortality factor 4 (pseudogene) [Source:HGNC Symbol;Acc:HGNC:15773]",0,{"v":0.0473,"d":"0.05"},"-inf","-inf",1,1,"down","no"]
["ENSG00000277297","ATP5A1P10","ENST00000622403","NA","NA","NA","NA","ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1 pseudogene 10 [Source:HGNC Symbol;Acc:HGNC:37668]",{"v":0.064132,"d":"0.06"},0,"inf","inf",1,1,"up","no"]
["ENSG00000255875","AC008813.1","ENST00000536597","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000253305","PCDHGB6","ENST00000520790;ENST00000616430","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005509(calcium ion binding);GO:0007155(cell adhesion);GO:0007156(homophilic cell adhesion via plasma membrane adhesion molecules);GO:0005886(plasma membrane);GO:0005887(integral component of plasma membrane);GO:0007399(nervous system development);GO:0007267(cell-cell signaling);GO:0007267(cell-cell signaling)","NA","NA","NA","protocadherin gamma subfamily B, 6 [Source:HGNC Symbol;Acc:HGNC:8713]",{"v":0.0284723339722796,"d":"0.03"},{"v":0.325980657180773,"d":"0.33"},{"v":0.0873436301973286,"d":"0.09"},{"v":-3.51715369576618,"d":"-3.52"},1,1,"down","no"]
["ENSG00000106304","SPAM1","ENST00000340011","GO:0016787(hydrolase activity);GO:0003824(catalytic activity);GO:0005975(carbohydrate metabolic process);GO:0008152(metabolic process);GO:0016798(hydrolase activity, acting on glycosyl bonds);GO:0004415(hyalurononglucosaminidase activity);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0007155(cell adhesion);GO:0005886(plasma membrane);GO:0031225(anchored component of membrane);GO:0035036(sperm-egg recognition);GO:0007339(binding of sperm to zona pellucida);GO:0007342(fusion of sperm to egg plasma membrane)","00531(Glycosaminoglycan degradation)","K01197","EC:3.2.1.35","sperm adhesion molecule 1 [Source:HGNC Symbol;Acc:HGNC:11217]",{"v":0.0339063275065963,"d":"0.03"},0,"inf","inf",1,1,"up","no"]
["ENSG00000232938","RPL23AP87","ENST00000425566","NA","NA","NA","NA","ribosomal protein L23a pseudogene 87 [Source:HGNC Symbol;Acc:HGNC:51578]",{"v":0.034177,"d":"0.03"},{"v":0.030335,"d":"0.03"},{"v":1.12665238173727,"d":"1.13"},{"v":0.172042453838859,"d":"0.17"},1,1,"up","no"]
["ENSG00000115665","SLC5A7","ENST00000264047","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005215(transporter activity);GO:0055085(transmembrane transport);GO:0015293(symporter activity);GO:0006811(ion transport);GO:0005886(plasma membrane);GO:0006814(sodium ion transport);GO:0030054(cell junction);GO:0045202(synapse);GO:0098793(presynapse);GO:0005887(integral component of plasma membrane);GO:0007269(neurotransmitter secretion);GO:0030425(dendrite);GO:0043204(perikaryon);GO:0031594(neuromuscular junction);GO:0030424(axon);GO:0007274(neuromuscular synaptic transmission);GO:0007271(synaptic transmission, cholinergic);GO:0042136(neurotransmitter biosynthetic process);GO:0015220(choline transmembrane transporter activity);GO:0008292(acetylcholine biosynthetic process);GO:0005307(choline:sodium symporter activity);GO:0033265(choline binding);GO:0015871(choline transport);GO:0043025(neuronal cell body)","04725(Cholinergic synapse);05231(Choline metabolism in cancer)","K14387","NA","solute carrier family 5 member 7 [Source:HGNC Symbol;Acc:HGNC:14025]",0,{"v":0.00407035913312693,"d":"0.00"},"-inf","-inf",1,1,"down","no"]
["ENSG00000181961","OR4A16","ENST00000314721","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0004930(G-protein coupled receptor activity);GO:0007186(G-protein coupled receptor signaling pathway);GO:0005886(plasma membrane);GO:0004871(signal transducer activity);GO:0007165(signal transduction);GO:0004984(olfactory receptor activity);GO:0007608(sensory perception of smell);GO:0050896(response to stimulus);GO:0050911(detection of chemical stimulus involved in sensory perception of smell);GO:0004888(transmembrane signaling receptor activity);GO:0050907(detection of chemical stimulus involved in sensory perception)","04740(Olfactory transduction)","K04257","NA","olfactory receptor family 4 subfamily A member 16 [Source:HGNC Symbol;Acc:HGNC:15153]",{"v":0.142651,"d":"0.14"},{"v":0.042205,"d":"0.04"},{"v":3.37995498163725,"d":"3.38"},{"v":1.75700403106331,"d":"1.76"},1,1,"up","no"]
["ENSG00000269586","CT45A10","ENST00000611668","NA","NA","NA","NA","cancer/testis antigen family 45 member A10 [Source:HGNC Symbol;Acc:HGNC:51263]",{"v":4.2326185770751E-3,"d":"0.00"},0,"inf","inf",1,1,"up","no"]
["ENSG00000257042","AC008011.2","ENST00000538113","NA","NA","NA","NA",null,{"v":0.129803,"d":"0.13"},0,"inf","inf",1,1,"up","no"]
["MSTRG.2252","AC116535.1","ENST00000499765","NA","NA","NA","NA",null,{"v":0.254618,"d":"0.25"},{"v":0.135774,"d":"0.14"},{"v":1.87530749628058,"d":"1.88"},{"v":0.907127175334594,"d":"0.91"},1,1,"up","no"]
["MSTRG.2761","AP003086.1","ENST00000513207","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000177181","RIMKLA","ENST00000431473","GO:0005524(ATP binding);GO:0003824(catalytic activity);GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0006464(cellular protein modification process);GO:0016874(ligase activity);GO:0005829(cytosol);GO:0008652(cellular amino acid biosynthetic process);GO:0072590(N-acetyl-L-aspartate-L-glutamate ligase activity)","00250(Alanine, aspartate and glutamate metabolism)","K18311","EC:6.3.2.41;EC:6.3.2.42","ribosomal modification protein rimK like family member A [Source:HGNC Symbol;Acc:HGNC:28725]",0,{"v":0.0176196033849237,"d":"0.02"},"-inf","-inf",1,1,"down","no"]
["MSTRG.10048","AP001434.1","ENST00000444977","NA","NA","NA","NA",null,{"v":0.267458,"d":"0.27"},{"v":0.32061,"d":"0.32"},{"v":0.834216025701007,"d":"0.83"},{"v":-0.261507067511227,"d":"-0.26"},1,1,"down","no"]
["ENSG00000063660","GPC1","ENST00000495100;ENST00000469694;ENST00000420138;ENST00000264039","GO:0016020(membrane);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0005886(plasma membrane);GO:0005576(extracellular region);GO:0043236(laminin binding);GO:0005578(proteinaceous extracellular matrix);GO:0005615(extracellular space);GO:0031225(anchored component of membrane);GO:0045121(membrane raft);GO:0050900(leukocyte migration);GO:0043395(heparan sulfate proteoglycan binding);GO:0005768(endosome);GO:0070062(extracellular exosome);GO:0005887(integral component of plasma membrane);GO:0005507(copper ion binding);GO:2001016(positive regulation of skeletal muscle cell differentiation);GO:0007411(axon guidance);GO:0043202(lysosomal lumen);GO:0001523(retinoid metabolic process);GO:0006024(glycosaminoglycan biosynthetic process);GO:0006027(glycosaminoglycan catabolic process);GO:0030203(glycosaminoglycan metabolic process);GO:0005796(Golgi lumen);GO:0017134(fibroblast growth factor binding);GO:0014037(Schwann cell differentiation);GO:0030200(heparan sulfate proteoglycan catabolic process);GO:0032288(myelin assembly);GO:0040037(negative regulation of fibroblast growth factor receptor signaling pathway);GO:0040037(negative regulation of fibroblast growth factor receptor signaling pathway)","05205(Proteoglycans in cancer);05418(Fluid shear stress and atherosclerosis);05418(Fluid shear stress and atherosclerosis)","K08107","NA","glypican 1 [Source:HGNC Symbol;Acc:HGNC:4449]",{"v":0.108096812615101,"d":"0.11"},{"v":0.0535171169429098,"d":"0.05"},{"v":2.0198549322157,"d":"2.02"},{"v":1.01425168105209,"d":"1.01"},1,1,"up","no"]
["ENSG00000236528","AL033528.2","ENST00000455431","NA","NA","NA","NA",null,{"v":0.059831,"d":"0.06"},{"v":0.004532,"d":"0.00"},{"v":13.2018976169462,"d":"13.20"},{"v":3.72267340975848,"d":"3.72"},1,1,"up","no"]
["ENSG00000136444","RSAD1","ENST00000258955;ENST00000506211;ENST00000515221;ENST00000443328;ENST00000513650;ENST00000504284;ENST00000510554;ENST00000509398","GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0003824(catalytic activity);GO:0005739(mitochondrion);GO:0051536(iron-sulfur cluster binding);GO:0051539(4 iron, 4 sulfur cluster binding);GO:0006779(porphyrin-containing compound biosynthetic process);GO:0004109(coproporphyrinogen oxidase activity);GO:0004109(coproporphyrinogen oxidase activity)","NA","NA","NA","radical S-adenosyl methionine domain containing 1 [Source:HGNC Symbol;Acc:HGNC:25634]",{"v":2.09517667508337,"d":"2.10"},{"v":2.14231383611243,"d":"2.14"},{"v":0.977997079496719,"d":"0.98"},{"v":-0.0320979378917459,"d":"-0.03"},1,1,"down","no"]
["ENSG00000196391","ZNF774","ENST00000379090;ENST00000560038;ENST00000354377","GO:0005634(nucleus);GO:0003676(nucleic acid binding);GO:0046872(metal ion binding);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0005515(protein binding);GO:0005515(protein binding)","NA","NA","NA","zinc finger protein 774 [Source:HGNC Symbol;Acc:HGNC:33108]",{"v":0.0321748828574786,"d":"0.03"},{"v":0.0347367863940783,"d":"0.03"},{"v":0.926248113238349,"d":"0.93"},{"v":-0.110529396226731,"d":"-0.11"},1,1,"down","no"]
["ENSG00000042304","C2orf83","ENST00000409066","GO:0006810(transport);GO:0016020(membrane);GO:0015403(thiamine uptake transmembrane transporter activity);GO:0071934(thiamine transmembrane transport)","NA","NA","NA","chromosome 2 open reading frame 83 [Source:HGNC Symbol;Acc:HGNC:25344]",{"v":0.00786408835341365,"d":"0.01"},0,"inf","inf",1,1,"up","no"]
["ENSG00000134569","LRP4","ENST00000378623","GO:0090090(negative regulation of canonical Wnt signaling pathway);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005509(calcium ion binding);GO:0005515(protein binding);GO:0007275(multicellular organism development);GO:0016055(Wnt signaling pathway);GO:0030154(cell differentiation);GO:0030509(BMP signaling pathway);GO:0030425(dendrite);GO:0005886(plasma membrane);GO:0006897(endocytosis);GO:0048513(animal organ development);GO:0014069(postsynaptic density);GO:0042813(Wnt-activated receptor activity);GO:0009986(cell surface);GO:0030971(receptor tyrosine kinase binding);GO:0050808(synapse organization);GO:0071340(skeletal muscle acetylcholine-gated channel clustering);GO:0031594(neuromuscular junction);GO:0043025(neuronal cell body);GO:0017147(Wnt-protein binding);GO:0097060(synaptic membrane);GO:0016600(flotillin complex);GO:0034185(apolipoprotein binding);GO:0042803(protein homodimerization activity);GO:0097110(scaffold protein binding);GO:0001822(kidney development);GO:0001932(regulation of protein phosphorylation);GO:0001942(hair follicle development);GO:0008104(protein localization);GO:0009953(dorsal/ventral pattern formation);GO:0009954(proximal/distal pattern formation);GO:0030178(negative regulation of Wnt signaling pathway);GO:0030279(negative regulation of ossification);GO:0030326(embryonic limb morphogenesis);GO:0042475(odontogenesis of dentin-containing tooth);GO:0042733(embryonic digit morphogenesis);GO:0043113(receptor clustering);GO:0044332(Wnt signaling pathway involved in dorsal/ventral axis specification);GO:0048813(dendrite morphogenesis);GO:0048856(anatomical structure development);GO:0050731(positive regulation of peptidyl-tyrosine phosphorylation);GO:0050771(negative regulation of axonogenesis);GO:0051124(synaptic growth at neuromuscular junction);GO:0051290(protein heterotetramerization);GO:0060173(limb development);GO:0060828(regulation of canonical Wnt signaling pathway);GO:0097104(postsynaptic membrane assembly);GO:0097105(presynaptic membrane assembly);GO:1901631(positive regulation of presynaptic membrane organization);GO:1904395(positive regulation of skeletal muscle acetylcholine-gated channel clustering);GO:0043235(receptor complex)","NA","NA","NA","LDL receptor related protein 4 [Source:HGNC Symbol;Acc:HGNC:6696]",{"v":0.0127495023845528,"d":"0.01"},{"v":0.0307699639409096,"d":"0.03"},{"v":0.414348954358115,"d":"0.41"},{"v":-1.27108181346149,"d":"-1.27"},1,1,"down","no"]
["ENSG00000112115","IL17A","ENST00000340057","GO:0005576(extracellular region);GO:0005515(protein binding);GO:0006954(inflammatory response);GO:0005125(cytokine activity);GO:0005615(extracellular space);GO:0006955(immune response);GO:0007267(cell-cell signaling);GO:0006915(apoptotic process);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0045672(positive regulation of osteoclast differentiation);GO:0032747(positive regulation of interleukin-23 production);GO:0008219(cell death);GO:0050832(defense response to fungus);GO:0071347(cellular response to interleukin-1);GO:0072537(fibroblast activation);GO:0097398(cellular response to interleukin-17);GO:1900017(positive regulation of cytokine production involved in inflammatory response);GO:2000778(positive regulation of interleukin-6 secretion);GO:0009897(external side of plasma membrane)","04060(Cytokine-cytokine receptor interaction);04659(Th17 cell differentiation);04657(IL-17 signaling pathway);05323(Rheumatoid arthritis);05321(Inflammatiory bowel disease (IBD))","K05489","NA","interleukin 17A [Source:HGNC Symbol;Acc:HGNC:5981]",{"v":0.011705,"d":"0.01"},0,"inf","inf",1,1,"up","no"]
["ENSG00000186204","CYP4F12","ENST00000324632;ENST00000548237;ENST00000550627;ENST00000551607;ENST00000547471;ENST00000550264;ENST00000546608;ENST00000517734","GO:0046872(metal ion binding);GO:0004497(monooxygenase activity);GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0005506(iron ion binding);GO:0016705(oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen);GO:0020037(heme binding);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005737(cytoplasm);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0070330(aromatase activity);GO:0043231(intracellular membrane-bounded organelle);GO:0016324(apical plasma membrane);GO:0031090(organelle membrane);GO:0001676(long-chain fatty acid metabolic process);GO:0019369(arachidonic acid metabolic process);GO:0003091(renal water homeostasis);GO:0019825(oxygen binding);GO:0000038(very long-chain fatty acid metabolic process);GO:0017144(drug metabolic process);GO:0055078(sodium ion homeostasis);GO:0008392(arachidonic acid epoxygenase activity);GO:0050051(leukotriene-B4 20-monooxygenase activity);GO:0003095(pressure natriuresis);GO:0019373(epoxygenase P450 pathway);GO:0036101(leukotriene B4 catabolic process);GO:0042360(vitamin E metabolic process);GO:0018685(alkane 1-monooxygenase activity);GO:0018685(alkane 1-monooxygenase activity)","NA","NA","NA","cytochrome P450 family 4 subfamily F member 12 [Source:HGNC Symbol;Acc:HGNC:18857]",{"v":0.0405429788824519,"d":"0.04"},{"v":0.118768535600822,"d":"0.12"},{"v":0.341361276177689,"d":"0.34"},{"v":-1.5506286857163,"d":"-1.55"},1,1,"down","no"]
["MSTRG.6721","AC243732.1","ENST00000612648","NA","NA","NA","NA",null,{"v":0.371832,"d":"0.37"},{"v":0.330386,"d":"0.33"},{"v":1.12544720417935,"d":"1.13"},{"v":0.170498380154875,"d":"0.17"},1,1,"up","no"]
["ENSG00000267296","CEBPA-AS1","ENST00000592982","NA","NA","NA","NA","CEBPA antisense RNA 1 (head to head) [Source:HGNC Symbol;Acc:HGNC:25710]",0,{"v":0.145299,"d":"0.15"},"-inf","-inf",1,1,"down","no"]
["ENSG00000125675","GRIA3","ENST00000620443;ENST00000611689;ENST00000622768;ENST00000477389","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005216(ion channel activity);GO:0006811(ion transport);GO:0034220(ion transmembrane transport);GO:0005886(plasma membrane);GO:0030054(cell junction);GO:0045202(synapse);GO:0045211(postsynaptic membrane);GO:0004872(receptor activity);GO:0004970(ionotropic glutamate receptor activity);GO:0005234(extracellular-glutamate-gated ion channel activity);GO:0035235(ionotropic glutamate receptor signaling pathway);GO:0060079(excitatory postsynaptic potential);GO:0032281(AMPA glutamate receptor complex);GO:0030666(endocytic vesicle membrane);GO:0007215(glutamate receptor signaling pathway);GO:0001540(amyloid-beta binding);GO:0004971(AMPA glutamate receptor activity);GO:0005231(excitatory extracellular ligand-gated ion channel activity);GO:0005231(excitatory extracellular ligand-gated ion channel activity)","04024(cAMP signaling pathway);04080(Neuroactive ligand-receptor interaction);04724(Glutamatergic synapse);04728(Dopaminergic synapse);04730(Long-term depression);04723(Retrograde endocannabinoid signaling);04713(Circadian entrainment);05202(Transcriptional misregulation in cancers);05031(Amphetamine addiction);05033(Nicotine addiction);05033(Nicotine addiction)","K05199","NA","glutamate ionotropic receptor AMPA type subunit 3 [Source:HGNC Symbol;Acc:HGNC:4573]",{"v":0.00660187769895126,"d":"0.01"},{"v":0.0118051583898828,"d":"0.01"},{"v":0.559236689666881,"d":"0.56"},{"v":-0.838469080625951,"d":"-0.84"},1,1,"down","no"]
["ENSG00000225361","PPP1R26-AS1","ENST00000603624","NA","NA","NA","NA","PPP1R26 antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:48717]",{"v":0.0130218536,"d":"0.01"},{"v":0.0244946912,"d":"0.02"},{"v":0.531619422905809,"d":"0.53"},{"v":-0.911534279930913,"d":"-0.91"},1,1,"down","no"]
["ENSG00000230773","AC092650.1","ENST00000587616;ENST00000447571","NA","NA","NA","NA",null,{"v":0.00642307532106907,"d":"0.01"},{"v":0.00791792294342242,"d":"0.01"},{"v":0.811207101529682,"d":"0.81"},{"v":-0.301857812742349,"d":"-0.30"},1,1,"down","no"]
["ENSG00000217874","OR4F7P","ENST00000402444","NA","NA","NA","NA","olfactory receptor family 4 subfamily F member 7 pseudogene [Source:HGNC Symbol;Acc:HGNC:15089]",{"v":0.023465,"d":"0.02"},0,"inf","inf",1,1,"up","no"]
["ENSG00000236980","C3orf84","ENST00000545770","NA","NA","NA","NA","chromosome 3 open reading frame 84 [Source:HGNC Symbol;Acc:HGNC:44666]",0,{"v":0.0259668878822197,"d":"0.03"},"-inf","-inf",1,1,"down","no"]
["MSTRG.7370","AC124287.1","ENST00000582249","NA","NA","NA","NA",null,{"v":0.0403,"d":"0.04"},{"v":0.024229,"d":"0.02"},{"v":1.66329605018779,"d":"1.66"},{"v":0.734044976878245,"d":"0.73"},1,1,"up","no"]
["ENSG00000279151","AL021920.1","ENST00000624517","NA","NA","NA","NA",null,{"v":0.056329,"d":"0.06"},0,"inf","inf",1,1,"up","no"]
["ENSG00000272842","AL391834.1","ENST00000609609","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000130957","FBP2","ENST00000375337","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0005654(nucleoplasm);GO:0016787(hydrolase activity);GO:0005975(carbohydrate metabolic process);GO:0005886(plasma membrane);GO:0016791(phosphatase activity);GO:0016311(dephosphorylation);GO:0005515(protein binding);GO:0003824(catalytic activity);GO:0008152(metabolic process);GO:0030054(cell junction);GO:0042802(identical protein binding);GO:0006094(gluconeogenesis);GO:0042578(phosphoric ester hydrolase activity);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0042132(fructose 1,6-bisphosphate 1-phosphatase activity);GO:0005986(sucrose biosynthetic process);GO:0006000(fructose metabolic process);GO:0006002(fructose 6-phosphate metabolic process);GO:0030388(fructose 1,6-bisphosphate metabolic process);GO:0030018(Z disc)","00010(Glycolysis / Gluconeogenesis);00030(Pentose phosphate pathway);00051(Fructose and mannose metabolism);04152(AMPK signaling pathway);04910(Insulin signaling pathway)","K03841","EC:3.1.3.11","fructose-bisphosphatase 2 [Source:HGNC Symbol;Acc:HGNC:3607]",{"v":0.045998,"d":"0.05"},{"v":0.023673,"d":"0.02"},{"v":1.94305749165716,"d":"1.94"},{"v":0.958328588366181,"d":"0.96"},1,1,"up","no"]
["MSTRG.7027","TOB1-AS1","ENST00000519432;ENST00000416263","NA","NA","NA","NA","TOB1 antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:44340]",{"v":0.437240557003257,"d":"0.44"},{"v":0.195673081433225,"d":"0.20"},{"v":2.23454628403994,"d":"2.23"},{"v":1.15998192750909,"d":"1.16"},1,1,"up","no"]
["ENSG00000153266","FEZF2","ENST00000283268","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006366(transcription from RNA polymerase II promoter);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0007275(multicellular organism development);GO:0007399(nervous system development);GO:0030154(cell differentiation);GO:0045944(positive regulation of transcription from RNA polymerase II promoter)","NA","NA","NA","FEZ family zinc finger 2 [Source:HGNC Symbol;Acc:HGNC:13506]",{"v":0.045706496124031,"d":"0.05"},0,"inf","inf",1,1,"up","no"]
["ENSG00000204414","CSHL1","ENST00000560999","GO:0005576(extracellular region);GO:0005179(hormone activity);GO:0046872(metal ion binding);GO:0008150(biological_process);GO:0005575(cellular_component)","NA","NA","NA","chorionic somatomammotropin hormone like 1 [Source:HGNC Symbol;Acc:HGNC:2442]",{"v":0.141447695101816,"d":"0.14"},0,"inf","inf",1,1,"up","no"]
["MSTRG.656","DLSTP1","ENST00000444241","NA","NA","NA","NA","dihydrolipoamide S-succinyltransferase pseudogene 1 [Source:HGNC Symbol;Acc:HGNC:2912]",{"v":0.189309,"d":"0.19"},{"v":0.13759,"d":"0.14"},{"v":1.37589214332437,"d":"1.38"},{"v":0.460367381093908,"d":"0.46"},1,1,"up","no"]
["MSTRG.12933","AL645931.1","ENST00000439737","NA","NA","NA","NA",null,{"v":0.062685,"d":"0.06"},0,"inf","inf",1,1,"up","no"]
["MSTRG.2782","AP000446.1","ENST00000530045","NA","NA","NA","NA",null,{"v":0.0180671578207381,"d":"0.02"},0,"inf","inf",1,1,"up","no"]
["ENSG00000267560","AC027514.2","ENST00000591014","NA","NA","NA","NA",null,{"v":0.270062,"d":"0.27"},{"v":0.214869,"d":"0.21"},{"v":1.25686813826099,"d":"1.26"},{"v":0.329833300310742,"d":"0.33"},1,1,"up","no"]
["ENSG00000206090","AP000350.1","ENST00000443377","NA","NA","NA","NA",null,0,{"v":0.060105,"d":"0.06"},"-inf","-inf",1,1,"down","no"]
["ENSG00000255760","LINC02422","ENST00000535163","NA","NA","NA","NA","long intergenic non-protein coding RNA 2422 [Source:HGNC Symbol;Acc:HGNC:53352]",{"v":0.78008,"d":"0.78"},{"v":0.684686,"d":"0.68"},{"v":1.13932517971742,"d":"1.14"},{"v":0.188179571638123,"d":"0.19"},1,1,"up","no"]
["ENSG00000267496","FAM215A","ENST00000632077;ENST00000588043","NA","NA","NA","NA","family with sequence similarity 215 member A (non-protein coding) [Source:HGNC Symbol;Acc:HGNC:17505]",0,{"v":0.0568382676767677,"d":"0.06"},"-inf","-inf",1,1,"down","no"]
["MSTRG.7438","STK25P1","ENST00000585406","NA","NA","NA","NA","serine/threonine kinase 25 pseudogene 1 [Source:HGNC Symbol;Acc:HGNC:50361]",{"v":0.120224,"d":"0.12"},{"v":0.147724,"d":"0.15"},{"v":0.81384202973112,"d":"0.81"},{"v":-0.297179306588178,"d":"-0.30"},1,1,"down","no"]
["ENSG00000165171","METTL27","ENST00000297873;ENST00000458679;ENST00000493174","GO:0005515(protein binding);GO:0005515(protein binding)","NA","NA","NA","methyltransferase like 27 [Source:HGNC Symbol;Acc:HGNC:19068]",{"v":0.287480944860449,"d":"0.29"},{"v":0.0686377835262083,"d":"0.07"},{"v":4.1883774517672,"d":"4.19"},{"v":2.06639146214813,"d":"2.07"},1,1,"up","no"]
["ENSG00000278943","AC079228.1","ENST00000624774","NA","NA","NA","NA",null,0,{"v":0.020007,"d":"0.02"},"-inf","-inf",1,1,"down","no"]
["ENSG00000168539","CHRM1","ENST00000306960","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0004930(G-protein coupled receptor activity);GO:0007186(G-protein coupled receptor signaling pathway);GO:0005887(integral component of plasma membrane);GO:0005886(plasma membrane);GO:0004871(signal transducer activity);GO:0007165(signal transduction);GO:0016907(G-protein coupled acetylcholine receptor activity);GO:0046541(saliva secretion);GO:0030054(cell junction);GO:0045202(synapse);GO:0045211(postsynaptic membrane);GO:0007399(nervous system development);GO:0004435(phosphatidylinositol phospholipase C activity);GO:0006464(cellular protein modification process);GO:0008283(cell proliferation);GO:0008284(positive regulation of cell proliferation);GO:0007205(protein kinase C-activating G-protein coupled receptor signaling pathway);GO:0007271(synaptic transmission, cholinergic);GO:0007197(adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway);GO:0007207(phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway);GO:0007213(G-protein coupled acetylcholine receptor signaling pathway);GO:0040012(regulation of locomotion);GO:0008144(drug binding);GO:0003056(regulation of vascular smooth muscle contraction);GO:0007274(neuromuscular synaptic transmission);GO:0043270(positive regulation of ion transport);GO:0050890(cognition);GO:0090316(positive regulation of intracellular protein transport);GO:0014069(postsynaptic density);GO:0030425(dendrite);GO:0032279(asymmetric synapse);GO:0043679(axon terminus)","04020(Calcium signaling pathway);04024(cAMP signaling pathway);04151(PI3K-Akt signaling pathway);04080(Neuroactive ligand-receptor interaction);04810(Regulation of actin cytoskeleton);04725(Cholinergic synapse)","K04129","NA","cholinergic receptor muscarinic 1 [Source:HGNC Symbol;Acc:HGNC:1950]",{"v":0.047342832,"d":"0.05"},{"v":0.037434864,"d":"0.04"},{"v":1.26467220503325,"d":"1.26"},{"v":0.338763496022314,"d":"0.34"},1,1,"up","no"]
["ENSG00000187569","DPPA3","ENST00000345088","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016569(covalent chromatin modification);GO:0007275(multicellular organism development);GO:0035064(methylated histone binding);GO:0040016(embryonic cleavage);GO:0044726(protection of DNA demethylation of female pronucleus);GO:1901536(negative regulation of DNA demethylation);GO:2000653(regulation of genetic imprinting);GO:0001939(female pronucleus)","NA","NA","NA","developmental pluripotency associated 3 [Source:HGNC Symbol;Acc:HGNC:19199]",{"v":0.081011,"d":"0.08"},{"v":0.003371,"d":"0.00"},{"v":24.0317413230495,"d":"24.03"},{"v":4.58686928380915,"d":"4.59"},1,1,"up","no"]
["ENSG00000266907","AC006116.1","ENST00000587908","NA","NA","NA","NA",null,0,{"v":0.168191,"d":"0.17"},"-inf","-inf",1,1,"down","no"]
["ENSG00000163254","CRYGC","ENST00000282141","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0007601(visual perception);GO:0005515(protein binding);GO:0005212(structural constituent of eye lens)","NA","NA","NA","crystallin gamma C [Source:HGNC Symbol;Acc:HGNC:2410]",{"v":0.16754,"d":"0.17"},{"v":0.072534,"d":"0.07"},{"v":2.30981332892161,"d":"2.31"},{"v":1.20777626275774,"d":"1.21"},1,1,"up","no"]
["ENSG00000268230","AC012313.3","ENST00000599109","NA","NA","NA","NA",null,{"v":0.140385111057576,"d":"0.14"},{"v":0.107145103830402,"d":"0.11"},{"v":1.31023356214008,"d":"1.31"},{"v":0.389824009401127,"d":"0.39"},1,1,"up","no"]
["ENSG00000087085","ACHE","ENST00000302913;ENST00000619863","GO:0005634(nucleus);GO:0016020(membrane);GO:0016787(hydrolase activity);GO:0007155(cell adhesion);GO:0042803(protein homodimerization activity);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0030054(cell junction);GO:0045202(synapse);GO:0007399(nervous system development);GO:0006260(DNA replication);GO:0031225(anchored component of membrane);GO:0052689(carboxylic ester hydrolase activity);GO:0001540(amyloid-beta binding);GO:0008283(cell proliferation);GO:0007517(muscle organ development);GO:0004104(cholinesterase activity);GO:0050714(positive regulation of protein secretion);GO:0048471(perinuclear region of cytoplasm);GO:0042136(neurotransmitter biosynthetic process);GO:0005794(Golgi apparatus);GO:0009611(response to wounding);GO:0007416(synapse assembly);GO:0042982(amyloid precursor protein metabolic process);GO:0005518(collagen binding);GO:0003990(acetylcholinesterase activity);GO:0043236(laminin binding);GO:0042166(acetylcholine binding);GO:0006656(phosphatidylcholine biosynthetic process);GO:0042135(neurotransmitter catabolic process);GO:0017171(serine hydrolase activity);GO:0001507(acetylcholine catabolic process in synaptic cleft);GO:0002076(osteoblast development);GO:0006581(acetylcholine catabolic process);GO:0032223(negative regulation of synaptic transmission, cholinergic);GO:0005605(basal lamina);GO:0043083(synaptic cleft);GO:0016021(integral component of membrane);GO:0043621(protein self-association);GO:0001919(regulation of receptor recycling);GO:0031623(receptor internalization);GO:0045212(neurotransmitter receptor biosynthetic process);GO:0051262(protein tetramerization);GO:0060041(retina development in camera-type eye);GO:0005615(extracellular space);GO:0009986(cell surface);GO:0031594(neuromuscular junction);GO:0031594(neuromuscular junction)","00564(Glycerophospholipid metabolism);04725(Cholinergic synapse);04725(Cholinergic synapse)","NA","NA","acetylcholinesterase (Cartwright blood group) [Source:HGNC Symbol;Acc:HGNC:108]",{"v":0.171110488340927,"d":"0.17"},{"v":0.0167933326186009,"d":"0.02"},{"v":10.189191879127,"d":"10.19"},{"v":3.34896772851,"d":"3.35"},1,1,"up","no"]
["ENSG00000122585","NPY","ENST00000407573;ENST00000405982","GO:0005794(Golgi apparatus);GO:0005576(extracellular region);GO:0065009(regulation of molecular function);GO:0005179(hormone activity);GO:0007218(neuropeptide signaling pathway);GO:0005615(extracellular space);GO:0001664(G-protein coupled receptor binding);GO:0004930(G-protein coupled receptor activity);GO:0005102(receptor binding);GO:0005184(neuropeptide hormone activity);GO:0007631(feeding behavior);GO:0006928(movement of cell or subcellular component);GO:0007268(chemical synaptic transmission);GO:0008283(cell proliferation);GO:0007586(digestion);GO:0006816(calcium ion transport);GO:0008015(blood circulation);GO:0031175(neuron projection development);GO:0032098(regulation of appetite);GO:0005246(calcium channel regulator activity);GO:0007187(G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger);GO:0007610(behavior);GO:0008343(adult feeding behavior);GO:0021954(central nervous system neuron development);GO:0021987(cerebral cortex development);GO:0032100(positive regulation of appetite);GO:0005623(cell);GO:0008217(regulation of blood pressure);GO:0005737(cytoplasm);GO:0005737(cytoplasm)","04024(cAMP signaling pathway);04923(Regulation of lipolysis in adipocyte);04920(Adipocytokine signaling pathway);05034(Alcoholism);05034(Alcoholism)","NA","NA","neuropeptide Y [Source:HGNC Symbol;Acc:HGNC:7955]",{"v":0.00409298045602606,"d":"0.00"},{"v":0.0495371878393051,"d":"0.05"},{"v":0.0826244006685115,"d":"0.08"},{"v":-3.59728828797379,"d":"-3.60"},1,1,"down","no"]
["ENSG00000169347","GP2","ENST00000302555","GO:0016020(membrane);GO:0005886(plasma membrane);GO:0005576(extracellular region);GO:0031225(anchored component of membrane);GO:0070062(extracellular exosome);GO:0006501(C-terminal protein lipidation)","NA","NA","NA","glycoprotein 2 [Source:HGNC Symbol;Acc:HGNC:4441]",{"v":0.00279345849802372,"d":"0.00"},0,"inf","inf",1,1,"up","no"]
["ENSG00000230323","LINC00159","ENST00000414877","NA","NA","NA","NA","long intergenic non-protein coding RNA 159 [Source:HGNC Symbol;Acc:HGNC:1285]",{"v":0.0284567622377622,"d":"0.03"},0,"inf","inf",1,1,"up","no"]
["ENSG00000257758","KRT18P20","ENST00000548986","NA","NA","NA","NA","keratin 18 pseudogene 20 [Source:HGNC Symbol;Acc:HGNC:33388]",{"v":0.040189,"d":"0.04"},{"v":0.071343,"d":"0.07"},{"v":0.563320858388349,"d":"0.56"},{"v":-0.827971202865549,"d":"-0.83"},1,1,"down","no"]
["ENSG00000180347","CCDC129","ENST00000319386","GO:0005102(receptor binding)","NA","NA","NA","coiled-coil domain containing 129 [Source:HGNC Symbol;Acc:HGNC:27363]",{"v":0.0141876146839636,"d":"0.01"},0,"inf","inf",1,1,"up","no"]
["ENSG00000279452","AC006277.1","ENST00000624348","NA","NA","NA","NA",null,{"v":0.12643,"d":"0.13"},0,"inf","inf",1,1,"up","no"]
["ENSG00000188937","NYX","ENST00000342595","GO:0005576(extracellular region);GO:0005578(proteinaceous extracellular matrix);GO:0050896(response to stimulus);GO:0005737(cytoplasm);GO:0003674(molecular_function);GO:0008150(biological_process);GO:0005622(intracellular);GO:0007601(visual perception);GO:0004860(protein kinase inhibitor activity);GO:0006469(negative regulation of protein kinase activity);GO:0019221(cytokine-mediated signaling pathway);GO:0046426(negative regulation of JAK-STAT cascade)","NA","NA","NA","nyctalopin [Source:HGNC Symbol;Acc:HGNC:8082]",0,{"v":0.088602875502008,"d":"0.09"},"-inf","-inf",1,1,"down","no"]
["ENSG00000275854","AC084824.4","ENST00000620106","NA","NA","NA","NA",null,0,{"v":0.436891,"d":"0.44"},"-inf","-inf",1,1,"down","no"]
["ENSG00000235812","ADAM21P1","ENST00000530196;ENST00000529267","NA","NA","NA","NA","ADAM metallopeptidase domain 21 pseudogene 1 [Source:HGNC Symbol;Acc:HGNC:19822]",{"v":0.0778477537862397,"d":"0.08"},0,"inf","inf",1,1,"up","no"]
["ENSG00000258415","AC060814.1","ENST00000554326","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000251688","LINC02507","ENST00000509370","NA","NA","NA","NA","long intergenic non-protein coding RNA 2507 [Source:HGNC Symbol;Acc:HGNC:53496]",0,{"v":0.013462,"d":"0.01"},"-inf","-inf",1,1,"down","no"]
["ENSG00000277701","AC159540.2","ENST00000613749;ENST00000621110;ENST00000618066","NA","NA","NA","NA",null,{"v":0.297397596348223,"d":"0.30"},{"v":0.126155410498859,"d":"0.13"},{"v":2.35739073871043,"d":"2.36"},{"v":1.23719090584267,"d":"1.24"},1,1,"up","no"]
["ENSG00000253140","AC026904.2","ENST00000521359","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000251694","USP17L9P","ENST00000508843","NA","NA","NA","NA","ubiquitin specific peptidase 17-like family member 9, pseudogene [Source:HGNC Symbol;Acc:HGNC:12615]",{"v":0.063976,"d":"0.06"},{"v":0.041687,"d":"0.04"},{"v":1.53467507856166,"d":"1.53"},{"v":0.617933240502637,"d":"0.62"},1,1,"up","no"]
["ENSG00000251193","AC112203.1","ENST00000506315","NA","NA","NA","NA",null,{"v":0.050394,"d":"0.05"},0,"inf","inf",1,1,"up","no"]
["ENSG00000243304","AC008494.1","ENST00000497612","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000262001","DLGAP1-AS2","ENST00000573177;ENST00000572856","NA","NA","NA","NA","DLGAP1 antisense RNA 2 [Source:HGNC Symbol;Acc:HGNC:28146]",{"v":0.032041885209713,"d":"0.03"},{"v":0.0809559640491958,"d":"0.08"},{"v":0.395794004629994,"d":"0.40"},{"v":-1.33717833585233,"d":"-1.34"},1,1,"down","no"]
["ENSG00000283258","AC007491.1","ENST00000637961","NA","NA","NA","NA",null,{"v":0.00529906681939672,"d":"0.01"},0,"inf","inf",1,1,"up","no"]
["MSTRG.3482","AC137834.2","ENST00000617433","NA","NA","NA","NA",null,0,{"v":0.130168,"d":"0.13"},"-inf","-inf",1,1,"down","no"]
["MSTRG.155","UBE2V2P3","ENST00000433562","NA","NA","NA","NA","ubiquitin conjugating enzyme E2 V2 pseudogene 3 [Source:HGNC Symbol;Acc:HGNC:44891]",0,0,1,0,1,1,"no","no"]
["ENSG00000271664","AC004890.3","ENST00000605566","NA","NA","NA","NA",null,0,{"v":0.077159,"d":"0.08"},"-inf","-inf",1,1,"down","no"]
["ENSG00000271208","Z99289.3","ENST00000605586","NA","NA","NA","NA",null,{"v":0.038364,"d":"0.04"},0,"inf","inf",1,1,"up","no"]
["MSTRG.13501","AC006042.2","ENST00000428660","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000274010","AC006011.2","ENST00000621313","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000006611","USH1C","ENST00000005226","GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0051015(actin filament binding);GO:0007605(sensory perception of sound);GO:0005856(cytoskeleton);GO:0042995(cell projection);GO:0005515(protein binding);GO:0030154(cell differentiation);GO:0005902(microvillus);GO:0005903(brush border);GO:0005886(plasma membrane);GO:0030507(spectrin binding);GO:0045202(synapse);GO:0045494(photoreceptor cell maintenance);GO:0050953(sensory perception of light stimulus);GO:0001917(photoreceptor inner segment);GO:0051017(actin filament bundle assembly);GO:0050957(equilibrioception);GO:0043623(cellular protein complex assembly);GO:0032420(stereocilium);GO:1904970(brush border assembly);GO:1904106(protein localization to microvillus);GO:0032532(regulation of microvillus length);GO:0045177(apical part of cell);GO:0042472(inner ear morphogenesis);GO:0001750(photoreceptor outer segment);GO:0000086(G2/M transition of mitotic cell cycle);GO:0030046(parallel actin filament bundle assembly);GO:0042491(auditory receptor cell differentiation);GO:0060122(inner ear receptor stereocilium organization)","NA","NA","NA","USH1 protein network component harmonin [Source:HGNC Symbol;Acc:HGNC:12597]",{"v":0.0473122145187602,"d":"0.05"},{"v":0.0172058931484502,"d":"0.02"},{"v":2.74976800742377,"d":"2.75"},{"v":1.45930990639816,"d":"1.46"},1,1,"up","no"]
["ENSG00000105675","ATP4A","ENST00000262623","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0000287(magnesium ion binding);GO:0016787(hydrolase activity);GO:0006811(ion transport);GO:0006813(potassium ion transport);GO:0005886(plasma membrane);GO:0006814(sodium ion transport);GO:0005615(extracellular space);GO:0015991(ATP hydrolysis coupled proton transport);GO:0015992(proton transport);GO:0005391(sodium:potassium-exchanging ATPase activity);GO:0010248(establishment or maintenance of transmembrane electrochemical gradient);GO:0034220(ion transmembrane transport);GO:0005887(integral component of plasma membrane);GO:0008900(hydrogen:potassium-exchanging ATPase activity)","00190(Oxidative phosphorylation);04971(Gastric acid secretion);04966(Collecting duct acid secretion)","K01542","EC:3.6.3.10","ATPase H+/K+ transporting alpha subunit [Source:HGNC Symbol;Acc:HGNC:819]",{"v":0.0368115150424274,"d":"0.04"},{"v":0.060628654924145,"d":"0.06"},{"v":0.607163643799847,"d":"0.61"},{"v":-0.719842688323678,"d":"-0.72"},1,1,"down","no"]
["ENSG00000140798","ABCC12","ENST00000528693;ENST00000311303","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0055085(transmembrane transport);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0042626(ATPase activity, coupled to transmembrane movement of substances);GO:0016887(ATPase activity);GO:0005739(mitochondrion);GO:0005739(mitochondrion)","02010(ABC transporters);02010(ABC transporters)","K05672","NA","ATP binding cassette subfamily C member 12 [Source:HGNC Symbol;Acc:HGNC:14640]",{"v":0.00689400724248927,"d":"0.01"},{"v":0.0218988454935622,"d":"0.02"},{"v":0.314811447229762,"d":"0.31"},{"v":-1.66744009355484,"d":"-1.67"},1,1,"down","no"]
["ENSG00000230960","AL109910.1","ENST00000452071","NA","NA","NA","NA",null,{"v":0.038648,"d":"0.04"},0,"inf","inf",1,1,"up","no"]
["ENSG00000279628","AC131280.1","ENST00000624067","NA","NA","NA","NA",null,0,{"v":0.00751473793444243,"d":"0.01"},"-inf","-inf",1,1,"down","no"]
["ENSG00000266777","AC090616.6","ENST00000582640","NA","NA","NA","NA",null,{"v":0.0180042917688266,"d":"0.02"},0,"inf","inf",1,1,"up","no"]
["ENSG00000248364","OR7E86P","ENST00000505858","NA","NA","NA","NA","olfactory receptor family 7 subfamily E member 86 pseudogene [Source:HGNC Symbol;Acc:HGNC:14694]",0,{"v":0.040094,"d":"0.04"},"-inf","-inf",1,1,"down","no"]
["MSTRG.8781","AC017083.2","ENST00000608069","NA","NA","NA","NA",null,0,{"v":0.092273,"d":"0.09"},"-inf","-inf",1,1,"down","no"]
["ENSG00000081479","LRP2","ENST00000263816","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0046872(metal ion binding);GO:0005509(calcium ion binding);GO:0005765(lysosomal membrane);GO:0005905(clathrin-coated pit);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0006897(endocytosis);GO:0070062(extracellular exosome);GO:0061024(membrane organization);GO:0017124(SH3 domain binding);GO:0005764(lysosome);GO:0016324(apical plasma membrane);GO:0001523(retinoid metabolic process);GO:0006629(lipid metabolic process);GO:0043235(receptor complex);GO:0042359(vitamin D metabolic process);GO:0030665(clathrin-coated vesicle membrane);GO:0006898(receptor-mediated endocytosis);GO:0005041(low-density lipoprotein receptor activity);GO:0042954(lipoprotein transporter activity);GO:0051087(chaperone binding);GO:0003281(ventricular septum development);GO:0006766(vitamin metabolic process);GO:0007507(heart development);GO:0008283(cell proliferation);GO:0030900(forebrain development);GO:0035904(aorta development);GO:0042953(lipoprotein transport);GO:0060976(coronary vasculature development);GO:0005768(endosome);GO:0005783(endoplasmic reticulum);GO:0005794(Golgi apparatus);GO:0005903(brush border);GO:0030139(endocytic vesicle);GO:0031526(brush border membrane);GO:0045177(apical part of cell)","04340(Hedgehog signaling pathway);04918(Thyroid hormone synthesis);04979(Cholesterol metabolism)","K06233","NA","LDL receptor related protein 2 [Source:HGNC Symbol;Acc:HGNC:6694]",{"v":0.0176979601476015,"d":"0.02"},{"v":0.00932535891758918,"d":"0.01"},{"v":1.89783152627189,"d":"1.90"},{"v":0.924351927553967,"d":"0.92"},1,1,"up","no"]
["ENSG00000265115","AC011824.1","ENST00000584863","NA","NA","NA","NA",null,{"v":0.045813,"d":"0.05"},0,"inf","inf",1,1,"up","no"]
["ENSG00000205549","C9orf92","ENST00000380685","NA","NA","NA","NA","chromosome 9 open reading frame 92 [Source:HGNC Symbol;Acc:HGNC:19054]",{"v":0.0561713061674009,"d":"0.06"},0,"inf","inf",1,1,"up","no"]
["ENSG00000242419","PCDHGC4","ENST00000617094","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005509(calcium ion binding);GO:0007155(cell adhesion);GO:0007156(homophilic cell adhesion via plasma membrane adhesion molecules);GO:0005886(plasma membrane);GO:0005887(integral component of plasma membrane);GO:0007399(nervous system development);GO:0007267(cell-cell signaling);GO:0050808(synapse organization)","NA","NA","NA","protocadherin gamma subfamily C, 4 [Source:HGNC Symbol;Acc:HGNC:8717]",{"v":0.0184638974668275,"d":"0.02"},{"v":0.0162661085645356,"d":"0.02"},{"v":1.13511460922397,"d":"1.14"},{"v":0.182837969596825,"d":"0.18"},1,1,"up","no"]
["ENSG00000125813","PAX1","ENST00000613128;ENST00000444366","GO:0005634(nucleus);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0007275(multicellular organism development);GO:0006366(transcription from RNA polymerase II promoter);GO:0001501(skeletal system development);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:0001077(transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0001756(somitogenesis);GO:0007389(pattern specification process);GO:0008283(cell proliferation);GO:0043367(CD4-positive, alpha-beta T cell differentiation);GO:0043374(CD8-positive, alpha-beta T cell differentiation);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0048538(thymus development);GO:0060017(parathyroid gland development);GO:0060349(bone morphogenesis);GO:0061056(sclerotome development);GO:0061056(sclerotome development)","NA","NA","NA","paired box 1 [Source:HGNC Symbol;Acc:HGNC:8615]",{"v":0.0263376174210077,"d":"0.03"},{"v":0.00746172092228864,"d":"0.01"},{"v":3.52969746460706,"d":"3.53"},{"v":1.81954453335039,"d":"1.82"},1,1,"up","no"]
["ENSG00000271129","AC009027.1","ENST00000604510","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000131096","PYY","ENST00000360085;ENST00000592796","GO:0005576(extracellular region);GO:0005515(protein binding);GO:0005179(hormone activity);GO:0005615(extracellular space);GO:0001664(G-protein coupled receptor binding);GO:0007186(G-protein coupled receptor signaling pathway);GO:0007267(cell-cell signaling);GO:0007631(feeding behavior);GO:0006928(movement of cell or subcellular component);GO:0008283(cell proliferation);GO:0007586(digestion);GO:0007010(cytoskeleton organization);GO:0005184(neuropeptide hormone activity);GO:0007218(neuropeptide signaling pathway);GO:0032098(regulation of appetite);GO:0032098(regulation of appetite)","04080(Neuroactive ligand-receptor interaction);04080(Neuroactive ligand-receptor interaction)","K05233","NA","peptide YY [Source:HGNC Symbol;Acc:HGNC:9748]",{"v":0.0435240643522439,"d":"0.04"},{"v":0.199787042337003,"d":"0.20"},{"v":0.217852288332228,"d":"0.22"},{"v":-2.19857782740789,"d":"-2.20"},1,1,"down","no"]
["ENSG00000163207","IVL","ENST00000368764","GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005813(centrosome);GO:0005515(protein binding);GO:0016604(nuclear body);GO:0031424(keratinization);GO:0070062(extracellular exosome);GO:0030674(protein binding, bridging);GO:0030216(keratinocyte differentiation);GO:0005198(structural molecule activity);GO:0070268(cornification);GO:0001533(cornified envelope);GO:0018149(peptide cross-linking);GO:0010224(response to UV-B);GO:0018153(isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine)","NA","NA","NA","involucrin [Source:HGNC Symbol;Acc:HGNC:6187]",{"v":0.047749,"d":"0.05"},{"v":0.021191,"d":"0.02"},{"v":2.25326789674862,"d":"2.25"},{"v":1.17201884945182,"d":"1.17"},1,1,"up","no"]
["MSTRG.13732","SPDYE5","ENST00000624640;ENST00000625065","NA","04114(Oocyte meiosis);04914(Progesterone-mediated oocyte maturation);04914(Progesterone-mediated oocyte maturation)","K08694","NA","speedy/RINGO cell cycle regulator family member E5 [Source:HGNC Symbol;Acc:HGNC:35464]",{"v":0.258104959699248,"d":"0.26"},{"v":0.090770727518797,"d":"0.09"},{"v":2.84348232909997,"d":"2.84"},{"v":1.50765883864954,"d":"1.51"},1,1,"up","no"]
["ENSG00000228212","OFD1P17","ENST00000437639","NA","NA","NA","NA","OFD1 pseudogene 17 [Source:HGNC Symbol;Acc:HGNC:1332]",{"v":0.017032,"d":"0.02"},0,"inf","inf",1,1,"up","no"]
["MSTRG.5430","AC103739.2","ENST00000559839","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000215840","AL592295.1","ENST00000400984","NA","NA","NA","NA",null,{"v":0.120621,"d":"0.12"},0,"inf","inf",1,1,"up","no"]
["MSTRG.10196","PRAMENP","ENST00000337471;ENST00000419303","NA","NA","NA","NA","PRAME N-terminal-like, pseudogene [Source:HGNC Symbol;Acc:HGNC:34302]",{"v":0.0857347792036854,"d":"0.09"},{"v":0.0450381750575847,"d":"0.05"},{"v":1.90360242381196,"d":"1.90"},{"v":0.928732196561695,"d":"0.93"},1,1,"up","no"]
["ENSG00000282917","AC107068.2","ENST00000634948;ENST00000634611","NA","NA","NA","NA",null,0,{"v":0.0476534509090909,"d":"0.05"},"-inf","-inf",1,1,"down","no"]
["ENSG00000265728","AP001099.1","ENST00000579385","NA","NA","NA","NA",null,{"v":0.048074,"d":"0.05"},{"v":0.099586,"d":"0.10"},{"v":0.482738537545438,"d":"0.48"},{"v":-1.05068609158442,"d":"-1.05"},1,1,"down","no"]
["ENSG00000231549","USMG5P1","ENST00000425964","NA","NA","NA","NA","USMG5 pseudogene 1 [Source:HGNC Symbol;Acc:HGNC:31716]",{"v":0.1665,"d":"0.17"},0,"inf","inf",1,1,"up","no"]
["ENSG00000189152","GRAPL","ENST00000583540;ENST00000344415;ENST00000577213","NA","NA","NA","NA","GRB2 related adaptor protein like [Source:HGNC Symbol;Acc:HGNC:37240]",{"v":0.752000679980276,"d":"0.75"},{"v":0.298285011341223,"d":"0.30"},{"v":2.52108101777875,"d":"2.52"},{"v":1.3340424815719,"d":"1.33"},1,1,"up","no"]
["ENSG00000184601","C14orf180","ENST00000557649","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005886(plasma membrane)","NA","NA","NA","chromosome 14 open reading frame 180 [Source:HGNC Symbol;Acc:HGNC:33795]",{"v":3.22488076416337E-3,"d":"0.00"},{"v":0.00286273287220026,"d":"0.00"},{"v":1.12650425594365,"d":"1.13"},{"v":0.171852764099034,"d":"0.17"},1,1,"up","no"]
["ENSG00000165379","LRFN5","ENST00000298119;ENST00000554171","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005615(extracellular space);GO:0005578(proteinaceous extracellular matrix);GO:0009986(cell surface);GO:0009986(cell surface)","NA","NA","NA","leucine rich repeat and fibronectin type III domain containing 5 [Source:HGNC Symbol;Acc:HGNC:20360]",{"v":0.0167432436482085,"d":"0.02"},{"v":0.0111463285016287,"d":"0.01"},{"v":1.50213082682445,"d":"1.50"},{"v":0.587010468638737,"d":"0.59"},1,1,"up","no"]
["MSTRG.14","FAM138A","ENST00000417324;ENST00000461467","NA","NA","NA","NA","family with sequence similarity 138 member A [Source:HGNC Symbol;Acc:HGNC:32334]",{"v":0.0666716185397867,"d":"0.07"},{"v":0.0834152370795734,"d":"0.08"},{"v":0.799273860196378,"d":"0.80"},{"v":-0.323238187413402,"d":"-0.32"},1,1,"down","no"]
["ENSG00000185372","OR2V1","ENST00000329365","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0004930(G-protein coupled receptor activity);GO:0007186(G-protein coupled receptor signaling pathway);GO:0005886(plasma membrane);GO:0004871(signal transducer activity);GO:0007165(signal transduction);GO:0004984(olfactory receptor activity);GO:0007608(sensory perception of smell);GO:0050896(response to stimulus);GO:0050911(detection of chemical stimulus involved in sensory perception of smell)","04740(Olfactory transduction)","K04257","NA","olfactory receptor family 2 subfamily V member 1 [Source:HGNC Symbol;Acc:HGNC:8280]",{"v":0.0727195992818671,"d":"0.07"},0,"inf","inf",1,1,"up","no"]
["ENSG00000175509","AL078621.2","ENST00000419351","NA","NA","NA","NA",null,{"v":0.118575,"d":"0.12"},{"v":0.055372,"d":"0.06"},{"v":2.14142526908907,"d":"2.14"},{"v":1.09857133130516,"d":"1.10"},1,1,"up","no"]
["ENSG00000213373","LINC00671","ENST00000417193;ENST00000301683","NA","NA","NA","NA","long intergenic non-protein coding RNA 671 [Source:HGNC Symbol;Acc:HGNC:44339]",{"v":0.195771989847716,"d":"0.20"},{"v":0.0354037840332257,"d":"0.04"},{"v":5.5296911105318,"d":"5.53"},{"v":2.46719889352503,"d":"2.47"},1,1,"up","no"]
["MSTRG.13770","GNAT3","ENST00000398291","GO:0005737(cytoplasm);GO:0005525(GTP binding);GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0007186(G-protein coupled receptor signaling pathway);GO:0007165(signal transduction);GO:0003924(GTPase activity);GO:0004871(signal transducer activity);GO:0019001(guanyl nucleotide binding);GO:0031683(G-protein beta/gamma-subunit complex binding);GO:0007188(adenylate cyclase-modulating G-protein coupled receptor signaling pathway);GO:0005886(plasma membrane);GO:0001664(G-protein coupled receptor binding);GO:0001580(detection of chemical stimulus involved in sensory perception of bitter taste);GO:0006457(protein folding);GO:0007193(adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway);GO:0035094(response to nicotine);GO:0050909(sensory perception of taste);GO:0050913(sensory perception of bitter taste);GO:0050916(sensory perception of sweet taste);GO:0050917(sensory perception of umami taste);GO:0001669(acrosomal vesicle);GO:0001750(photoreceptor outer segment);GO:0001917(photoreceptor inner segment);GO:0005834(heterotrimeric G-protein complex);GO:0005930(axoneme);GO:0016324(apical plasma membrane);GO:0043234(protein complex)","04973(Carbohydrate digestion and absorption);04742(Taste transduction)","K19729","NA","G protein subunit alpha transducin 3 [Source:HGNC Symbol;Acc:HGNC:22800]",{"v":0.026019,"d":"0.03"},0,"inf","inf",1,1,"up","no"]
["ENSG00000088002","SULT2B1","ENST00000323090;ENST00000597923","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0043231(intracellular membrane-bounded organelle);GO:0005829(cytosol);GO:0016740(transferase activity);GO:0006629(lipid metabolic process);GO:0005783(endoplasmic reticulum);GO:0008202(steroid metabolic process);GO:0005515(protein binding);GO:0008146(sulfotransferase activity);GO:0070062(extracellular exosome);GO:0003676(nucleic acid binding);GO:0004027(alcohol sulfotransferase activity);GO:0015485(cholesterol binding);GO:0050294(steroid sulfotransferase activity);GO:1990239(steroid hormone binding);GO:0000103(sulfate assimilation);GO:0050427(3'-phosphoadenosine 5'-phosphosulfate metabolic process);GO:0050427(3'-phosphoadenosine 5'-phosphosulfate metabolic process)","00140(Steroid hormone biosynthesis);00140(Steroid hormone biosynthesis)","K01015","EC:2.8.2.2","sulfotransferase family 2B member 1 [Source:HGNC Symbol;Acc:HGNC:11459]",{"v":0.0118093043940468,"d":"0.01"},{"v":2.69453756201276E-3,"d":"0.00"},{"v":4.38268315889629,"d":"4.38"},{"v":2.13181438463222,"d":"2.13"},1,1,"up","no"]
["ENSG00000280114","AL021920.2","ENST00000624828","NA","NA","NA","NA",null,{"v":0.027231,"d":"0.03"},{"v":0.054929,"d":"0.05"},{"v":0.495749057874711,"d":"0.50"},{"v":-1.01231806413929,"d":"-1.01"},1,1,"down","no"]
["ENSG00000258451","AL163636.1","ENST00000554286","NA","NA","NA","NA",null,0,{"v":0.045259,"d":"0.05"},"-inf","-inf",1,1,"down","no"]
["ENSG00000224157","HCG14","ENST00000444986","NA","NA","NA","NA","HLA complex group 14 (non-protein coding) [Source:HGNC Symbol;Acc:HGNC:18323]",0,{"v":0.516997,"d":"0.52"},"-inf","-inf",1,1,"down","no"]
["MSTRG.5171","USP3-AS1","ENST00000559737;ENST00000560350;ENST00000559357;ENST00000558831","NA","NA","NA","NA","USP3 antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:44140]",{"v":0.0791889241169978,"d":"0.08"},{"v":0.0329558609271523,"d":"0.03"},{"v":2.40287833147621,"d":"2.40"},{"v":1.26476360018656,"d":"1.26"},1,1,"up","no"]
["ENSG00000112494","UNC93A","ENST00000230256","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005886(plasma membrane);GO:0003674(molecular_function);GO:0008150(biological_process)","NA","NA","NA","unc-93 homolog A (C. elegans) [Source:HGNC Symbol;Acc:HGNC:12570]",{"v":0.0231544809188588,"d":"0.02"},{"v":0.0201376717302705,"d":"0.02"},{"v":1.1498092346025,"d":"1.15"},{"v":0.201394522802423,"d":"0.20"},1,1,"up","no"]
["MSTRG.8429","KIR2DP1","ENST00000415311","NA","NA","NA","NA","killer cell immunoglobulin like receptor, two Ig domains pseudogene 1 [Source:HGNC Symbol;Acc:HGNC:16344]",{"v":0.607897,"d":"0.61"},{"v":0.446459,"d":"0.45"},{"v":1.36159647358436,"d":"1.36"},{"v":0.445299205687525,"d":"0.45"},1,1,"up","no"]
["ENSG00000269535","AC010320.4","ENST00000594379","NA","NA","NA","NA",null,0,{"v":0.023949,"d":"0.02"},"-inf","-inf",1,1,"down","no"]
["ENSG00000231437","LINC01750","ENST00000442751;ENST00000438293","NA","NA","NA","NA","long intergenic non-protein coding RNA 1750 [Source:HGNC Symbol;Acc:HGNC:52538]",{"v":0.0116934384401114,"d":"0.01"},{"v":0.0381257590529248,"d":"0.04"},{"v":0.306707033003041,"d":"0.31"},{"v":-1.7050668459144,"d":"-1.71"},1,1,"down","no"]
["ENSG00000164176","EDIL3","ENST00000296591","GO:0046872(metal ion binding);GO:0005509(calcium ion binding);GO:0007155(cell adhesion);GO:0005576(extracellular region);GO:0007275(multicellular organism development);GO:0005178(integrin binding);GO:0070062(extracellular exosome);GO:0031012(extracellular matrix);GO:1903561(extracellular vesicle);GO:0010811(positive regulation of cell-substrate adhesion)","NA","NA","NA","EGF like repeats and discoidin domains 3 [Source:HGNC Symbol;Acc:HGNC:3173]",{"v":0.0087191648658069,"d":"0.01"},{"v":0.00568261519693273,"d":"0.01"},{"v":1.53435778486518,"d":"1.53"},{"v":0.617634932817823,"d":"0.62"},1,1,"up","no"]
["ENSG00000100053","CRYBB3","ENST00000215855","GO:0007601(visual perception);GO:0005515(protein binding);GO:0005212(structural constituent of eye lens)","NA","NA","NA","crystallin beta B3 [Source:HGNC Symbol;Acc:HGNC:2400]",{"v":0.15157,"d":"0.15"},{"v":0.029269,"d":"0.03"},{"v":5.17851651918412,"d":"5.18"},{"v":2.37253887070367,"d":"2.37"},1,1,"up","no"]
["ENSG00000010310","GIPR","ENST00000588816;ENST00000591322;ENST00000591224;ENST00000590918","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0004930(G-protein coupled receptor activity);GO:0007186(G-protein coupled receptor signaling pathway);GO:0005886(plasma membrane);GO:0004871(signal transducer activity);GO:0007165(signal transduction);GO:0004888(transmembrane signaling receptor activity);GO:0007166(cell surface receptor signaling pathway);GO:0016519(gastric inhibitory peptide receptor activity);GO:0038192(gastric inhibitory peptide signaling pathway);GO:0006091(generation of precursor metabolites and energy);GO:0007584(response to nutrient);GO:0007190(activation of adenylate cyclase activity);GO:0050796(regulation of insulin secretion);GO:0017046(peptide hormone binding);GO:0002029(desensitization of G-protein coupled receptor protein signaling pathway);GO:0007204(positive regulation of cytosolic calcium ion concentration);GO:0009749(response to glucose);GO:0030819(positive regulation of cAMP biosynthetic process);GO:0031018(endocrine pancreas development);GO:0032024(positive regulation of insulin secretion);GO:0048678(response to axon injury);GO:0051592(response to calcium ion);GO:0070542(response to fatty acid);GO:0070542(response to fatty acid)","04024(cAMP signaling pathway);04080(Neuroactive ligand-receptor interaction);04080(Neuroactive ligand-receptor interaction)","K04580","NA","gastric inhibitory polypeptide receptor [Source:HGNC Symbol;Acc:HGNC:4271]",{"v":0.707024465160473,"d":"0.71"},{"v":0.117137390202703,"d":"0.12"},{"v":6.03585638997921,"d":"6.04"},{"v":2.59355848049522,"d":"2.59"},1,1,"up","no"]
["ENSG00000215454","KRTAP10-4","ENST00000400374","GO:0005515(protein binding);GO:0005882(intermediate filament);GO:0045095(keratin filament);GO:0005829(cytosol);GO:0031424(keratinization)","NA","NA","NA","keratin associated protein 10-4 [Source:HGNC Symbol;Acc:HGNC:20521]",0,{"v":0.0631728548910524,"d":"0.06"},"-inf","-inf",1,1,"down","no"]
["ENSG00000165623","UCMA","ENST00000378681","GO:0005576(extracellular region);GO:0005578(proteinaceous extracellular matrix);GO:0045667(regulation of osteoblast differentiation);GO:0045668(negative regulation of osteoblast differentiation);GO:0005615(extracellular space);GO:0016235(aggresome);GO:0048471(perinuclear region of cytoplasm)","NA","NA","NA","upper zone of growth plate and cartilage matrix associated [Source:HGNC Symbol;Acc:HGNC:25205]",0,{"v":0.0550351145958987,"d":"0.06"},"-inf","-inf",1,1,"down","no"]
["ENSG00000234139","AL035420.1","ENST00000450129","NA","NA","NA","NA",null,0,{"v":0.029503275659824,"d":"0.03"},"-inf","-inf",1,1,"down","no"]
["MSTRG.14902","MIR4668","ENST00000582284","NA","NA","NA","NA","microRNA 4668 [Source:HGNC Symbol;Acc:HGNC:41545]",{"v":0.160325,"d":"0.16"},{"v":0.007604,"d":"0.01"},{"v":21.0842977380326,"d":"21.08"},{"v":4.39809706496397,"d":"4.40"},1,1,"up","no"]
["MSTRG.2173","UBQLNL","ENST00000380184","NA","NA","NA","NA","ubiquilin like [Source:HGNC Symbol;Acc:HGNC:28294]",{"v":0.066003,"d":"0.07"},{"v":0.129264,"d":"0.13"},{"v":0.510606201262533,"d":"0.51"},{"v":-0.969717035645317,"d":"-0.97"},1,1,"down","no"]
["ENSG00000249259","AC027613.1","ENST00000513136","NA","NA","NA","NA",null,{"v":0.0185963641259321,"d":"0.02"},0,"inf","inf",1,1,"up","no"]
["ENSG00000238063","LINC01685","ENST00000634732","NA","NA","NA","NA","long intergenic non-protein coding RNA 1685 [Source:HGNC Symbol;Acc:HGNC:52473]",0,{"v":0.0236535611222445,"d":"0.02"},"-inf","-inf",1,1,"down","no"]
["ENSG00000152782","PANK1","ENST00000461829;ENST00000307534","GO:0005737(cytoplasm);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0004594(pantothenate kinase activity);GO:0015937(coenzyme A biosynthetic process);GO:0005829(cytosol);GO:0009108(coenzyme biosynthetic process);GO:0005634(nucleus);GO:0030118(clathrin coat);GO:0055037(recycling endosome);GO:0071944(cell periphery);GO:0071944(cell periphery)","00770(Pantothenate and CoA biosynthesis);00770(Pantothenate and CoA biosynthesis)","K09680","EC:2.7.1.33","pantothenate kinase 1 [Source:HGNC Symbol;Acc:HGNC:8598]",{"v":0.0883005425504059,"d":"0.09"},{"v":0.0852235579994763,"d":"0.09"},{"v":1.036104859069,"d":"1.04"},{"v":0.0511700184718044,"d":"0.05"},1,1,"up","no"]
["ENSG00000182489","XKRX","ENST00000372956","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005886(plasma membrane)","NA","NA","NA","XK related, X-linked [Source:HGNC Symbol;Acc:HGNC:29845]",{"v":0.172350453143535,"d":"0.17"},{"v":0.0793461921708185,"d":"0.08"},{"v":2.17213263079461,"d":"2.17"},{"v":1.11911219704086,"d":"1.12"},1,1,"up","no"]
["ENSG00000160188","RSPH1","ENST00000493019;ENST00000291536","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0031514(motile cilium);GO:0005829(cytosol);GO:0042995(cell projection);GO:0005515(protein binding);GO:0051321(meiotic cell cycle);GO:0005929(cilium);GO:0035082(axoneme assembly);GO:0007286(spermatid development);GO:0000794(condensed nuclear chromosome);GO:0001520(outer dense fiber);GO:0036126(sperm flagellum);GO:0072687(meiotic spindle);GO:0072687(meiotic spindle)","NA","NA","NA","radial spoke head 1 homolog [Source:HGNC Symbol;Acc:HGNC:12371]",0,{"v":0.0983328480589023,"d":"0.10"},"-inf","-inf",1,1,"down","no"]
["ENSG00000134115","CNTN6","ENST00000446702","GO:0016020(membrane);GO:0007155(cell adhesion);GO:0005886(plasma membrane);GO:0007399(nervous system development);GO:0005112(Notch binding);GO:0022008(neurogenesis);GO:0030182(neuron differentiation);GO:0045747(positive regulation of Notch signaling pathway);GO:0007219(Notch signaling pathway);GO:0031225(anchored component of membrane);GO:0007417(central nervous system development);GO:0016021(integral component of membrane)","NA","NA","NA","contactin 6 [Source:HGNC Symbol;Acc:HGNC:2176]",{"v":0.00428932832349257,"d":"0.00"},{"v":0.00606174467704419,"d":"0.01"},{"v":0.70760623418143,"d":"0.71"},{"v":-0.498981336312053,"d":"-0.50"},1,1,"down","no"]
["ENSG00000275340","FGD5P1","ENST00000611158","NA","NA","NA","NA","FYVE, RhoGEF and PH domain containing 5 pseudogene 1 [Source:HGNC Symbol;Acc:HGNC:44498]",{"v":0.0132858335487206,"d":"0.01"},0,"inf","inf",1,1,"up","no"]
["MSTRG.380","AL033529.1;ZBTB8A;ZBTB8B","ENST00000480336;ENST00000373510;ENST00000609129","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0003674(molecular_function);GO:0008150(biological_process);GO:0005575(cellular_component);GO:0003677(DNA binding)","NA","NA","NA","zinc finger and BTB domain containing 8A [Source:HGNC Symbol;Acc:HGNC:24172];zinc finger and BTB domain containing 8B [Source:HGNC Symbol;Acc:HGNC:37057]",{"v":0.0147138887230019,"d":"0.01"},{"v":0.0138746615905245,"d":"0.01"},{"v":1.0604863136302,"d":"1.06"},{"v":0.0847260019290557,"d":"0.08"},1,1,"up","no"]
["ENSG00000129965","INS-IGF2","ENST00000356578","GO:0005576(extracellular region);GO:0005179(hormone activity)","04014(Ras signaling pathway);04010(MAPK signaling pathway);04151(PI3K-Akt signaling pathway);05200(Pathways in cancer);05205(Proteoglycans in cancer);05225(Hepatocellular carcinoma)","NA","NA","INS-IGF2 readthrough [Source:HGNC Symbol;Acc:HGNC:33527]",0,{"v":0.00595579181961196,"d":"0.01"},"-inf","-inf",1,1,"down","no"]
["ENSG00000282997","AL162456.1","ENST00000634535","NA","NA","NA","NA",null,0,{"v":0.022744,"d":"0.02"},"-inf","-inf",1,1,"down","no"]
["ENSG00000162849","KIF26B","ENST00000479506;ENST00000366518;ENST00000407071","GO:0005737(cytoplasm);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0003777(microtubule motor activity);GO:0005856(cytoskeleton);GO:0008017(microtubule binding);GO:0007275(multicellular organism development);GO:0005874(microtubule);GO:0005871(kinesin complex);GO:0022409(positive regulation of cell-cell adhesion);GO:0030010(establishment of cell polarity);GO:0072092(ureteric bud invasion);GO:0003774(motor activity);GO:0007018(microtubule-based movement);GO:0007018(microtubule-based movement)","NA","NA","NA","kinesin family member 26B [Source:HGNC Symbol;Acc:HGNC:25484]",{"v":0.0575426609039783,"d":"0.06"},{"v":0.0216189781989863,"d":"0.02"},{"v":2.66167347847533,"d":"2.66"},{"v":1.41233359909444,"d":"1.41"},1,1,"up","no"]
["ENSG00000145888","GLRA1","ENST00000274576","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0046872(metal ion binding);GO:0005216(ion channel activity);GO:0006811(ion transport);GO:0005887(integral component of plasma membrane);GO:0008270(zinc ion binding);GO:0005886(plasma membrane);GO:0042995(cell projection);GO:0030054(cell junction);GO:0045202(synapse);GO:0045211(postsynaptic membrane);GO:0005254(chloride channel activity);GO:0006821(chloride transport);GO:0034707(chloride channel complex);GO:0007218(neuropeptide signaling pathway);GO:0005230(extracellular ligand-gated ion channel activity);GO:0030425(dendrite);GO:0060079(excitatory postsynaptic potential);GO:0005515(protein binding);GO:0071230(cellular response to amino acid stimulus);GO:0043204(perikaryon);GO:0043231(intracellular membrane-bounded organelle);GO:0034220(ion transmembrane transport);GO:2000344(positive regulation of acrosome reaction);GO:0016594(glycine binding);GO:0022824(transmitter-gated ion channel activity);GO:0043005(neuron projection);GO:0043025(neuronal cell body);GO:0016934(extracellular-glycine-gated chloride channel activity);GO:0060012(synaptic transmission, glycinergic);GO:1902476(chloride transmembrane transport);GO:0042391(regulation of membrane potential);GO:0071294(cellular response to zinc ion);GO:0006936(muscle contraction);GO:0030977(taurine binding);GO:0001964(startle response);GO:0051970(negative regulation of transmission of nerve impulse);GO:0060080(inhibitory postsynaptic potential);GO:0071361(cellular response to ethanol);GO:0097305(response to alcohol);GO:0016933(extracellular-glycine-gated ion channel activity);GO:0001508(action potential);GO:0002087(regulation of respiratory gaseous exchange by neurological system process);GO:0006820(anion transport);GO:0007268(chemical synaptic transmission);GO:0007340(acrosome reaction);GO:0007601(visual perception);GO:0007628(adult walking behavior);GO:0043576(regulation of respiratory gaseous exchange);GO:0050884(neuromuscular process controlling posture);GO:0050905(neuromuscular process);GO:0051260(protein homooligomerization);GO:0051291(protein heterooligomerization);GO:0060013(righting reflex);GO:0005622(intracellular);GO:0005783(endoplasmic reticulum);GO:0009897(external side of plasma membrane);GO:0060077(inhibitory synapse)","04080(Neuroactive ligand-receptor interaction)","K05193","NA","glycine receptor alpha 1 [Source:HGNC Symbol;Acc:HGNC:4326]",{"v":0.0139988060805259,"d":"0.01"},{"v":0.0466268837304848,"d":"0.05"},{"v":0.300230359837954,"d":"0.30"},{"v":-1.73585822261558,"d":"-1.74"},1,1,"down","no"]
["MSTRG.11745","AP002026.1","ENST00000500358;ENST00000506454;ENST00000506160;ENST00000499178","NA","NA","NA","NA",null,{"v":0.0941300756302521,"d":"0.09"},{"v":0.0710349131177895,"d":"0.07"},{"v":1.32512410445504,"d":"1.33"},{"v":0.406127481560629,"d":"0.41"},1,1,"up","no"]
["ENSG00000282600","AC245369.7","ENST00000631386","NA","NA","NA","NA",null,{"v":0.105741,"d":"0.11"},{"v":0.094175,"d":"0.09"},{"v":1.12281391027343,"d":"1.12"},{"v":0.167118842278162,"d":"0.17"},1,1,"up","no"]
["ENSG00000268089","GABRQ","ENST00000598523","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005216(ion channel activity);GO:0006811(ion transport);GO:0005886(plasma membrane);GO:0030054(cell junction);GO:0045202(synapse);GO:0045211(postsynaptic membrane);GO:0005254(chloride channel activity);GO:0006821(chloride transport);GO:0034707(chloride channel complex);GO:1902476(chloride transmembrane transport);GO:0004890(GABA-A receptor activity);GO:0005230(extracellular ligand-gated ion channel activity);GO:0034220(ion transmembrane transport);GO:0005887(integral component of plasma membrane);GO:1902711(GABA-A receptor complex);GO:0007165(signal transduction);GO:0004888(transmembrane signaling receptor activity);GO:0043235(receptor complex);GO:0005326(neurotransmitter transporter activity);GO:0006836(neurotransmitter transport)","04080(Neuroactive ligand-receptor interaction);04727(GABAergic synapse);04723(Retrograde endocannabinoid signaling);05032(Morphine addiction);05033(Nicotine addiction)","K05192","NA","gamma-aminobutyric acid type A receptor theta subunit [Source:HGNC Symbol;Acc:HGNC:14454]",0,{"v":0.012667,"d":"0.01"},"-inf","-inf",1,1,"down","no"]
["ENSG00000180269","GPR139","ENST00000570682","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0004930(G-protein coupled receptor activity);GO:0007186(G-protein coupled receptor signaling pathway);GO:0005886(plasma membrane);GO:0004871(signal transducer activity);GO:0007165(signal transduction);GO:0007218(neuropeptide signaling pathway);GO:0008188(neuropeptide receptor activity);GO:0046983(protein dimerization activity);GO:0007200(phospholipase C-activating G-protein coupled receptor signaling pathway)","NA","NA","NA","G protein-coupled receptor 139 [Source:HGNC Symbol;Acc:HGNC:19995]",{"v":0.090073613317757,"d":"0.09"},{"v":0.0198091851635514,"d":"0.02"},{"v":4.54706302021403,"d":"4.55"},{"v":2.18493499931452,"d":"2.18"},1,1,"up","no"]
["ENSG00000231615","AL645568.2","ENST00000432815","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000147127","RAB41","ENST00000374473;ENST00000509895","GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005525(GTP binding);GO:0000166(nucleotide binding);GO:0003924(GTPase activity);GO:0005515(protein binding);GO:0006891(intra-Golgi vesicle-mediated transport);GO:0005794(Golgi apparatus);GO:0042147(retrograde transport, endosome to Golgi);GO:0000139(Golgi membrane);GO:0006890(retrograde vesicle-mediated transport, Golgi to ER);GO:0006890(retrograde vesicle-mediated transport, Golgi to ER)","NA","NA","NA","RAB41, member RAS oncogene family [Source:HGNC Symbol;Acc:HGNC:18293]",{"v":0.0665919263392857,"d":"0.07"},{"v":0.001578734375,"d":"0.00"},{"v":42.1805766655874,"d":"42.18"},{"v":5.39850691374813,"d":"5.40"},1,1,"up","no"]
["ENSG00000233966","UBE2SP1","ENST00000450587","NA","NA","NA","NA","ubiquitin conjugating enzyme E2 S pseudogene 1 [Source:HGNC Symbol;Acc:HGNC:30864]",0,0,1,0,1,1,"no","no"]
["ENSG00000228071","RPL7P47","ENST00000497299","NA","NA","NA","NA","ribosomal protein L7 pseudogene 47 [Source:HGNC Symbol;Acc:HGNC:35913]",0,{"v":0.054158,"d":"0.05"},"-inf","-inf",1,1,"down","no"]
["ENSG00000230116","AL445669.1","ENST00000426743","NA","NA","NA","NA",null,{"v":0.068082,"d":"0.07"},0,"inf","inf",1,1,"up","no"]
["ENSG00000269067","ZNF728","ENST00000594710","GO:0003676(nucleic acid binding);GO:0046872(metal ion binding);GO:0006355(regulation of transcription, DNA-templated);GO:0005622(intracellular);GO:0003700(transcription factor activity, sequence-specific DNA binding)","NA","NA","NA","zinc finger protein 728 [Source:HGNC Symbol;Acc:HGNC:32463]",{"v":0.0232157048357664,"d":"0.02"},{"v":0.0208136998175182,"d":"0.02"},{"v":1.11540499955834,"d":"1.12"},{"v":0.157567642669873,"d":"0.16"},1,1,"up","no"]
["MSTRG.5609","GLIS2","ENST00000262366","GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0043433(negative regulation of sequence-specific DNA binding transcription factor activity);GO:0005634(nucleus);GO:0003676(nucleic acid binding);GO:0005737(cytoplasm);GO:0016607(nuclear speck);GO:0046872(metal ion binding);GO:0006366(transcription from RNA polymerase II promoter);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0007275(multicellular organism development);GO:0007399(nervous system development);GO:0030154(cell differentiation);GO:0045893(positive regulation of transcription, DNA-templated);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0045892(negative regulation of transcription, DNA-templated);GO:0044212(transcription regulatory region DNA binding);GO:0001077(transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0045879(negative regulation of smoothened signaling pathway);GO:0000977(RNA polymerase II regulatory region sequence-specific DNA binding);GO:0001822(kidney development);GO:0060994(regulation of transcription from RNA polymerase II promoter involved in kidney development);GO:0061005(cell differentiation involved in kidney development);GO:1900182(positive regulation of protein localization to nucleus);GO:0097730(non-motile cilium)","NA","NA","NA","GLIS family zinc finger 2 [Source:HGNC Symbol;Acc:HGNC:29450]",{"v":0.097957,"d":"0.10"},{"v":0.306507,"d":"0.31"},{"v":0.319591395955068,"d":"0.32"},{"v":-1.64569952635879,"d":"-1.65"},1,1,"down","no"]
["MSTRG.8281","AC011466.2","ENST00000594589","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000229196","AC087071.1","ENST00000469264;ENST00000470348","NA","NA","NA","NA",null,{"v":0.102191204771372,"d":"0.10"},0,"inf","inf",1,1,"up","no"]
["ENSG00000188730","VWC2","ENST00000340652","GO:0005576(extracellular region);GO:0005578(proteinaceous extracellular matrix);GO:0030054(cell junction);GO:0045202(synapse);GO:0005604(basement membrane);GO:0005615(extracellular space);GO:0003674(molecular_function);GO:0010811(positive regulation of cell-substrate adhesion);GO:0030514(negative regulation of BMP signaling pathway);GO:0045666(positive regulation of neuron differentiation);GO:0005614(interstitial matrix);GO:0032281(AMPA glutamate receptor complex)","NA","NA","NA","von Willebrand factor C domain containing 2 [Source:HGNC Symbol;Acc:HGNC:30200]",{"v":0.013147,"d":"0.01"},{"v":0.000485,"d":"0.00"},{"v":27.1072164948454,"d":"27.11"},{"v":4.76060507249477,"d":"4.76"},1,1,"up","no"]
["ENSG00000021645","NRXN3","ENST00000281127;ENST00000556003;ENST00000335750;ENST00000554738;ENST00000635466","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0007269(neurotransmitter secretion);GO:0051965(positive regulation of synapse assembly);GO:0098793(presynapse);GO:0007268(chemical synaptic transmission);GO:0007416(synapse assembly);GO:0090129(positive regulation of synapse maturation);GO:0046872(metal ion binding);GO:0007155(cell adhesion);GO:0005886(plasma membrane);GO:0005887(integral component of plasma membrane);GO:0004872(receptor activity);GO:0007411(axon guidance);GO:0050839(cell adhesion molecule binding);GO:0007612(learning);GO:0035176(social behavior);GO:0097109(neuroligin family protein binding);GO:0007158(neuron cell-cell adhesion);GO:0030534(adult behavior);GO:0071625(vocalization behavior);GO:0065009(regulation of molecular function);GO:0005246(calcium channel regulator activity);GO:0043234(protein complex);GO:0001525(angiogenesis);GO:0007165(signal transduction);GO:0004888(transmembrane signaling receptor activity);GO:0004888(transmembrane signaling receptor activity)","04514(Cell adhesion molecules (CAMs));04514(Cell adhesion molecules (CAMs))","K07377","NA","neurexin 3 [Source:HGNC Symbol;Acc:HGNC:8010]",{"v":0.0149671510782105,"d":"0.01"},{"v":0.0190313441905375,"d":"0.02"},{"v":0.786447395851958,"d":"0.79"},{"v":-0.346577825472198,"d":"-0.35"},1,1,"down","no"]
["ENSG00000259425","AC011767.1","ENST00000560434","NA","NA","NA","NA",null,0,{"v":0.0266533086876155,"d":"0.03"},"-inf","-inf",1,1,"down","no"]
["ENSG00000119227","PIGZ","ENST00000238138;ENST00000412723","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016740(transferase activity);GO:0016757(transferase activity, transferring glycosyl groups);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0097502(mannosylation);GO:0006506(GPI anchor biosynthetic process);GO:0000026(alpha-1,2-mannosyltransferase activity);GO:0000030(mannosyltransferase activity);GO:0000030(mannosyltransferase activity)","00563(Glycosylphosphatidylinositol(GPI)-anchor biosynthesis);00563(Glycosylphosphatidylinositol(GPI)-anchor biosynthesis)","K08098","EC:2.4.1.-","phosphatidylinositol glycan anchor biosynthesis class Z [Source:HGNC Symbol;Acc:HGNC:30596]",{"v":0.23846756649019,"d":"0.24"},{"v":0.109900670196201,"d":"0.11"},{"v":2.16984633546332,"d":"2.17"},{"v":1.11759287727127,"d":"1.12"},1,1,"up","no"]
["ENSG00000107187","LHX3","ENST00000371748;ENST00000619587","GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006355(regulation of transcription, DNA-templated);GO:0006366(transcription from RNA polymerase II promoter);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0043565(sequence-specific DNA binding);GO:0045893(positive regulation of transcription, DNA-templated);GO:0001228(transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:0001076(transcription factor activity, RNA polymerase II transcription factor binding);GO:0001077(transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0001890(placenta development);GO:0008045(motor neuron axon guidance);GO:0009953(dorsal/ventral pattern formation);GO:0021520(spinal cord motor neuron cell fate specification);GO:0021521(ventral spinal cord interneuron specification);GO:0021526(medial motor column neuron differentiation);GO:0021527(spinal cord association neuron differentiation);GO:0021983(pituitary gland development);GO:0030154(cell differentiation);GO:0030324(lung development);GO:0043066(negative regulation of apoptotic process);GO:0005622(intracellular);GO:0005667(transcription factor complex);GO:0009887(animal organ morphogenesis);GO:0048839(inner ear development);GO:0001085(RNA polymerase II transcription factor binding);GO:0001085(RNA polymerase II transcription factor binding)","NA","NA","NA","LIM homeobox 3 [Source:HGNC Symbol;Acc:HGNC:6595]",{"v":0.0225204787957268,"d":"0.02"},{"v":0.0232449485270314,"d":"0.02"},{"v":0.968833240027952,"d":"0.97"},{"v":-0.04567973109292,"d":"-0.05"},1,1,"down","no"]
["ENSG00000144488","ESPNL","ENST00000343063","GO:0005737(cytoplasm);GO:0051015(actin filament binding);GO:0031941(filamentous actin);GO:0051017(actin filament bundle assembly)","NA","NA","NA","espin like [Source:HGNC Symbol;Acc:HGNC:27937]",{"v":0.0371935479298769,"d":"0.04"},{"v":0.0274827661320403,"d":"0.03"},{"v":1.35334077185613,"d":"1.35"},{"v":0.436525156362046,"d":"0.44"},1,1,"up","no"]
["ENSG00000184302","SIX6","ENST00000327720","GO:0005634(nucleus);GO:0006355(regulation of transcription, DNA-templated);GO:0006366(transcription from RNA polymerase II promoter);GO:0003677(DNA binding);GO:0000981(RNA polymerase II transcription factor activity, sequence-specific DNA binding);GO:0007275(multicellular organism development);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0001654(eye development);GO:0007601(visual perception);GO:0009887(animal organ morphogenesis);GO:0001205(transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding)","NA","NA","NA","SIX homeobox 6 [Source:HGNC Symbol;Acc:HGNC:10892]",0,{"v":0.028404,"d":"0.03"},"-inf","-inf",1,1,"down","no"]
["ENSG00000147378","FATE1","ENST00000370350","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005739(mitochondrion);GO:0005515(protein binding);GO:0006915(apoptotic process);GO:0005741(mitochondrial outer membrane);GO:0031625(ubiquitin protein ligase binding);GO:0043066(negative regulation of apoptotic process);GO:0051562(negative regulation of mitochondrial calcium ion concentration);GO:0044233(ER-mitochondrion membrane contact site)","NA","NA","NA","fetal and adult testis expressed 1 [Source:HGNC Symbol;Acc:HGNC:24683]",{"v":0.017102,"d":"0.02"},0,"inf","inf",1,1,"up","no"]
["ENSG00000112238","PRDM13","ENST00000369214","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0008168(methyltransferase activity);GO:0016740(transferase activity);GO:0032259(methylation);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0016571(histone methylation);GO:0003682(chromatin binding);GO:0042054(histone methyltransferase activity);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0022008(neurogenesis)","NA","NA","NA","PR/SET domain 13 [Source:HGNC Symbol;Acc:HGNC:13998]",{"v":0.048230398046398,"d":"0.05"},{"v":0.0373238778998779,"d":"0.04"},{"v":1.29221294142525,"d":"1.29"},{"v":0.36984382871958,"d":"0.37"},1,1,"up","no"]
["ENSG00000185155","MIXL1","ENST00000366810","GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0005634(nucleus);GO:0006355(regulation of transcription, DNA-templated);GO:0006366(transcription from RNA polymerase II promoter);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0043565(sequence-specific DNA binding);GO:0007275(multicellular organism development);GO:0030154(cell differentiation);GO:0048565(digestive tract development);GO:0042803(protein homodimerization activity);GO:0000790(nuclear chromatin);GO:0001085(RNA polymerase II transcription factor binding);GO:0000980(RNA polymerase II distal enhancer sequence-specific DNA binding);GO:0007507(heart development);GO:0001103(RNA polymerase II repressing transcription factor binding);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:0001190(transcriptional activator activity, RNA polymerase II transcription factor binding);GO:0000987(core promoter proximal region sequence-specific DNA binding);GO:0001077(transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0001205(transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding);GO:0007369(gastrulation);GO:0035987(endodermal cell differentiation);GO:0002244(hematopoietic progenitor cell differentiation);GO:0007492(endoderm development);GO:0042802(identical protein binding);GO:0001706(endoderm formation);GO:0030097(hemopoiesis);GO:0042074(cell migration involved in gastrulation);GO:1901533(negative regulation of hematopoietic progenitor cell differentiation);GO:2000382(positive regulation of mesoderm development)","NA","NA","NA","Mix paired-like homeobox [Source:HGNC Symbol;Acc:HGNC:13363]",{"v":0.149443154263184,"d":"0.15"},{"v":0.0899433711187777,"d":"0.09"},{"v":1.66152493957372,"d":"1.66"},{"v":0.732507948118297,"d":"0.73"},1,1,"up","no"]
["ENSG00000177558","FAM187B","ENST00000324675","GO:0016020(membrane);GO:0016021(integral component of membrane)","NA","NA","NA","family with sequence similarity 187 member B [Source:HGNC Symbol;Acc:HGNC:26366]",{"v":0.066752,"d":"0.07"},0,"inf","inf",1,1,"up","no"]
["ENSG00000215343","ZNF705D","ENST00000400085","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0005622(intracellular)","NA","NA","NA","zinc finger protein 705D [Source:HGNC Symbol;Acc:HGNC:33202]",{"v":1.459E-3,"d":"0.00"},0,"inf","inf",1,1,"up","no"]
["ENSG00000235979","AC004448.4","ENST00000582654","NA","NA","NA","NA",null,{"v":2.9671404722156E-3,"d":"0.00"},0,"inf","inf",1,1,"up","no"]
["ENSG00000278937","AL137141.1","ENST00000624622","NA","NA","NA","NA",null,0,{"v":0.009434,"d":"0.01"},"-inf","-inf",1,1,"down","no"]
["ENSG00000258834","DUX4L4","ENST00000566884","NA","NA","NA","NA","double homeobox 4 like 4 [Source:HGNC Symbol;Acc:HGNC:38686]",{"v":0.002893,"d":"0.00"},0,"inf","inf",1,1,"up","no"]
["ENSG00000229887","HNRNPA1P6","ENST00000631770;ENST00000394002","NA","NA","NA","NA","heterogeneous nuclear ribonucleoprotein A1 pseudogene 6 [Source:HGNC Symbol;Acc:HGNC:5032]",0,{"v":0.0765126710435383,"d":"0.08"},"-inf","-inf",1,1,"down","no"]
["ENSG00000140465","CYP1A1","ENST00000379727","GO:0016020(membrane);GO:0046872(metal ion binding);GO:0004497(monooxygenase activity);GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005506(iron ion binding);GO:0016705(oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen);GO:0005515(protein binding);GO:0020037(heme binding);GO:0016712(oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen);GO:0070330(aromatase activity);GO:0070988(demethylation);GO:0003824(catalytic activity);GO:0008395(steroid hydroxylase activity);GO:0016679(oxidoreductase activity, acting on diphenols and related substances as donors);GO:0016711(flavonoid 3'-monooxygenase activity);GO:0019899(enzyme binding);GO:0032451(demethylase activity);GO:0001666(response to hypoxia);GO:0001889(liver development);GO:0006778(porphyrin-containing compound metabolic process);GO:0007568(aging);GO:0008283(cell proliferation);GO:0009308(amine metabolic process);GO:0009404(toxin metabolic process);GO:0009611(response to wounding);GO:0009615(response to virus);GO:0009624(response to nematode);GO:0009635(response to herbicide);GO:0009636(response to toxic substance);GO:0009804(coumarin metabolic process);GO:0009812(flavonoid metabolic process);GO:0010033(response to organic substance);GO:0010041(response to iron(III) ion);GO:0014070(response to organic cyclic compound);GO:0017143(insecticide metabolic process);GO:0018894(dibenzo-p-dioxin metabolic process);GO:0019341(dibenzo-p-dioxin catabolic process);GO:0032094(response to food);GO:0032496(response to lipopolysaccharide);GO:0032502(developmental process);GO:0033189(response to vitamin A);GO:0035902(response to immobilization stress);GO:0042493(response to drug);GO:0042904(9-cis-retinoic acid biosynthetic process);GO:0043010(camera-type eye development);GO:0046483(heterocycle metabolic process);GO:0046677(response to antibiotic);GO:0046685(response to arsenic-containing substance);GO:0048565(digestive tract development);GO:0050665(hydrogen peroxide biosynthetic process);GO:0055093(response to hyperoxia);GO:0060137(maternal process involved in parturition);GO:0070365(hepatocyte differentiation);GO:0071280(cellular response to copper ion);GO:1900087(positive regulation of G1/S transition of mitotic cell cycle);GO:0005737(cytoplasm);GO:0005739(mitochondrion);GO:0043231(intracellular membrane-bounded organelle);GO:0031090(organelle membrane);GO:0019216(regulation of lipid metabolic process);GO:0042359(vitamin D metabolic process);GO:0019825(oxygen binding);GO:0070576(vitamin D 24-hydroxylase activity);GO:0101020(estrogen 16-alpha-hydroxylase activity);GO:0002933(lipid hydroxylation);GO:0008202(steroid metabolic process);GO:0009692(ethylene metabolic process);GO:0017144(drug metabolic process);GO:0019373(epoxygenase P450 pathway);GO:0071407(cellular response to organic cyclic compound);GO:0097267(omega-hydroxylase P450 pathway)","00140(Steroid hormone biosynthesis);00380(Tryptophan metabolism);00830(Retinol metabolism);00980(Metabolism of xenobiotics by cytochrome P450);04913(Ovarian Steroidogenesis);05204(Chemical carcinogenesis)","K07408","EC:1.14.14.1","cytochrome P450 family 1 subfamily A member 1 [Source:HGNC Symbol;Acc:HGNC:2595]",{"v":0.0149640873362445,"d":"0.01"},{"v":0.0265639126637555,"d":"0.03"},{"v":0.563323917137474,"d":"0.56"},{"v":-0.827963369265661,"d":"-0.83"},1,1,"down","no"]
["MSTRG.14005","AC083880.1","ENST00000608266","NA","NA","NA","NA",null,{"v":0.096079,"d":"0.10"},0,"inf","inf",1,1,"up","no"]
["MSTRG.7511","AC120349.1","ENST00000599498","NA","NA","NA","NA",null,0,{"v":0.174243,"d":"0.17"},"-inf","-inf",1,1,"down","no"]
["ENSG00000168334","XIRP1","ENST00000340369","GO:0003723(RNA binding);GO:0003779(actin binding);GO:0030036(actin cytoskeleton organization);GO:0005515(protein binding);GO:0030054(cell junction);GO:0005925(focal adhesion);GO:0007507(heart development);GO:0001725(stress fiber);GO:0031941(filamentous actin);GO:0032091(negative regulation of protein binding)","NA","NA","NA","xin actin binding repeat containing 1 [Source:HGNC Symbol;Acc:HGNC:14301]",{"v":0.0776288820163909,"d":"0.08"},{"v":0.0810152126179063,"d":"0.08"},{"v":0.958201299582013,"d":"0.96"},{"v":-0.0615993247282131,"d":"-0.06"},1,1,"down","no"]
["ENSG00000182013","PNMA8A","ENST00000313683","NA","NA","NA","NA","paraneoplastic Ma antigen family member 8A [Source:HGNC Symbol;Acc:HGNC:25578]",{"v":0.0415371818181818,"d":"0.04"},0,"inf","inf",1,1,"up","no"]
["ENSG00000253785","AC008429.2","ENST00000523057","NA","NA","NA","NA",null,{"v":0.127613,"d":"0.13"},0,"inf","inf",1,1,"up","no"]
["ENSG00000159212","CLIC6","ENST00000360731","GO:0006810(transport);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005244(voltage-gated ion channel activity);GO:0006811(ion transport);GO:0034765(regulation of ion transmembrane transport);GO:0005886(plasma membrane);GO:0005254(chloride channel activity);GO:0006821(chloride transport);GO:0034707(chloride channel complex);GO:0005634(nucleus);GO:0070062(extracellular exosome);GO:1902476(chloride transmembrane transport)","NA","NA","NA","chloride intracellular channel 6 [Source:HGNC Symbol;Acc:HGNC:2065]",{"v":0.015923,"d":"0.02"},{"v":0.028124,"d":"0.03"},{"v":0.566171241644147,"d":"0.57"},{"v":-0.820689624681276,"d":"-0.82"},1,1,"down","no"]
["ENSG00000254461","AP001107.4","ENST00000533576","NA","NA","NA","NA",null,{"v":0.353441,"d":"0.35"},{"v":0.289007,"d":"0.29"},{"v":1.2229496171373,"d":"1.22"},{"v":0.290364969193659,"d":"0.29"},1,1,"up","no"]
["ENSG00000178919","FOXE1","ENST00000375123","GO:0005634(nucleus);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0043565(sequence-specific DNA binding);GO:0045893(positive regulation of transcription, DNA-templated);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0009653(anatomical structure morphogenesis);GO:0030154(cell differentiation);GO:0045892(negative regulation of transcription, DNA-templated);GO:0000981(RNA polymerase II transcription factor activity, sequence-specific DNA binding);GO:0006590(thyroid hormone generation);GO:0016477(cell migration);GO:0030878(thyroid gland development);GO:0031069(hair follicle morphogenesis);GO:0048538(thymus development);GO:0048562(embryonic organ morphogenesis);GO:0060021(palate development);GO:0060022(hard palate development);GO:0060023(soft palate development);GO:0060465(pharynx development);GO:1904888(cranial skeletal system development)","NA","NA","NA","forkhead box E1 [Source:HGNC Symbol;Acc:HGNC:3806]",{"v":0.014847,"d":"0.01"},{"v":0.013178,"d":"0.01"},{"v":1.12665047806951,"d":"1.13"},{"v":0.172040016162076,"d":"0.17"},1,1,"up","no"]
["ENSG00000246145","RRS1-AS1","ENST00000499642","NA","NA","NA","NA","RRS1 antisense RNA 1 (head to head) [Source:HGNC Symbol;Acc:HGNC:50465]",{"v":5.633E-3,"d":"0.01"},{"v":0.003414,"d":"0.00"},{"v":1.64997070884593,"d":"1.65"},{"v":0.72244041321181,"d":"0.72"},1,1,"up","no"]
["ENSG00000182938","OTOP3","ENST00000580749","GO:0003676(nucleic acid binding);GO:0016020(membrane);GO:0016021(integral component of membrane)","NA","NA","NA","otopetrin 3 [Source:HGNC Symbol;Acc:HGNC:19658]",{"v":0.019902,"d":"0.02"},{"v":0.059264,"d":"0.06"},{"v":0.335819384449244,"d":"0.34"},{"v":-1.57424258575106,"d":"-1.57"},1,1,"down","no"]
["ENSG00000116544","DLGAP3","ENST00000373347","GO:0016020(membrane);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0030054(cell junction);GO:0045202(synapse);GO:0045211(postsynaptic membrane);GO:0023052(signaling);GO:0014069(postsynaptic density);GO:0019904(protein domain specific binding);GO:0006461(protein complex assembly);GO:0001540(amyloid-beta binding)","NA","NA","NA","DLG associated protein 3 [Source:HGNC Symbol;Acc:HGNC:30368]",{"v":0.0931577410108122,"d":"0.09"},{"v":0.142366583857179,"d":"0.14"},{"v":0.654351172071863,"d":"0.65"},{"v":-0.611862997032497,"d":"-0.61"},1,1,"down","no"]
["ENSG00000180481","GLIPR1L2","ENST00000320460;ENST00000550916","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016021(integral component of membrane)","NA","NA","NA","GLI pathogenesis related 1 like 2 [Source:HGNC Symbol;Acc:HGNC:28592]",{"v":0.0523341994722955,"d":"0.05"},{"v":0.0445808179419525,"d":"0.04"},{"v":1.17391743553109,"d":"1.17"},{"v":0.231330943764336,"d":"0.23"},1,1,"up","no"]
["ENSG00000135222","CSN2","ENST00000353151","GO:0006810(transport);GO:0005215(transporter activity);GO:0005576(extracellular region);GO:0005515(protein binding);GO:0005615(extracellular space);GO:0005509(calcium ion binding);GO:0004857(enzyme inhibitor activity);GO:0006816(calcium ion transport);GO:0004869(cysteine-type endopeptidase inhibitor activity);GO:0007595(lactation);GO:2000117(negative regulation of cysteine-type endopeptidase activity);GO:1903488(negative regulation of lactation)","04917(Prolactin signaling pathway)","K17107","NA","casein beta [Source:HGNC Symbol;Acc:HGNC:2447]",{"v":0.004018,"d":"0.00"},{"v":0.044833,"d":"0.04"},{"v":0.0896214841746035,"d":"0.09"},{"v":-3.48001157136721,"d":"-3.48"},1,1,"down","no"]
["ENSG00000104499","GML","ENST00000220940","GO:0005622(intracellular);GO:0016020(membrane);GO:0005886(plasma membrane);GO:0031225(anchored component of membrane);GO:0006915(apoptotic process);GO:0019898(extrinsic component of membrane);GO:0008285(negative regulation of cell proliferation);GO:0006977(DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest)","NA","NA","NA","glycosylphosphatidylinositol anchored molecule like [Source:HGNC Symbol;Acc:HGNC:4375]",0,{"v":0.0259041670212766,"d":"0.03"},"-inf","-inf",1,1,"down","no"]
["ENSG00000204866","IGFL2","ENST00000593592;ENST00000434646;ENST00000377693","GO:0005576(extracellular region);GO:0005576(extracellular region)","NA","NA","NA","IGF like family member 2 [Source:HGNC Symbol;Acc:HGNC:32929]",{"v":0.0591030247320692,"d":"0.06"},{"v":0.0421426545754328,"d":"0.04"},{"v":1.40245139580086,"d":"1.40"},{"v":0.487950772793333,"d":"0.49"},1,1,"up","no"]
["ENSG00000092345","DAZL","ENST00000250863;ENST00000399444;ENST00000454457","GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0007275(multicellular organism development);GO:0030154(cell differentiation);GO:0007283(spermatogenesis);GO:0045948(positive regulation of translational initiation);GO:0005515(protein binding);GO:0008494(translation activator activity);GO:0007281(germ cell development);GO:0006417(regulation of translation);GO:0003730(mRNA 3'-UTR binding);GO:0070935(3'-UTR-mediated mRNA stabilization);GO:0042802(identical protein binding);GO:0001556(oocyte maturation);GO:0007147(female meiosis II);GO:0045836(positive regulation of meiotic nuclear division);GO:0005844(polysome);GO:0045727(positive regulation of translation);GO:0045727(positive regulation of translation)","NA","NA","NA","deleted in azoospermia like [Source:HGNC Symbol;Acc:HGNC:2685]",{"v":0.0234525932250069,"d":"0.02"},{"v":3.35155604516662E-4,"d":"0.00"},{"v":69.9752380952382,"d":"69.98"},{"v":6.12877258555636,"d":"6.13"},1,1,"up","no"]
["ENSG00000242736","TRBV1","ENST00000476502","NA","NA","NA","NA","T-cell receptor beta variable 1 (pseudogene) [Source:HGNC Symbol;Acc:HGNC:12176]",0,0,1,0,1,1,"no","no"]
["MSTRG.15152","AL590627.1","ENST00000626603;ENST00000629344","NA","NA","NA","NA",null,{"v":0.0847605790371493,"d":"0.08"},{"v":0.0218649071266111,"d":"0.02"},{"v":3.87655792665087,"d":"3.88"},{"v":1.95477622299407,"d":"1.95"},1,1,"up","no"]
["ENSG00000213432","RPL17P34","ENST00000394133","NA","NA","NA","NA","ribosomal protein L17 pseudogene 34 [Source:HGNC Symbol;Acc:HGNC:36756]",{"v":0.061127,"d":"0.06"},0,"inf","inf",1,1,"up","no"]
["ENSG00000263503","MAPK8IP1P2","ENST00000580257","NA","NA","NA","NA","mitogen-activated protein kinase 8 interacting protein 1 pseudogene 2 [Source:HGNC Symbol;Acc:HGNC:52402]",{"v":0.05238,"d":"0.05"},{"v":0.030994,"d":"0.03"},{"v":1.69000451700329,"d":"1.69"},{"v":0.757027102513104,"d":"0.76"},1,1,"up","no"]
["MSTRG.12239","AC008906.1","ENST00000512856","NA","NA","NA","NA",null,{"v":0.413483811188811,"d":"0.41"},{"v":0.311335756243756,"d":"0.31"},{"v":1.32809612418909,"d":"1.33"},{"v":0.40935956902837,"d":"0.41"},1,1,"up","no"]
["ENSG00000259932","AC051619.7","ENST00000568314","NA","NA","NA","NA",null,0,{"v":0.053643,"d":"0.05"},"-inf","-inf",1,1,"down","no"]
["MSTRG.3919","LINC02340","ENST00000620494","NA","NA","NA","NA","long intergenic non-protein coding RNA 2340 [Source:HGNC Symbol;Acc:HGNC:53260]",{"v":0.660644994535519,"d":"0.66"},{"v":0.534015647540984,"d":"0.53"},{"v":1.23712666019738,"d":"1.24"},{"v":0.306993214691027,"d":"0.31"},1,1,"up","no"]
["ENSG00000229855","AC008568.1","ENST00000597452;ENST00000433406","NA","NA","NA","NA",null,{"v":0.00416252488020641,"d":"0.00"},{"v":0.00554969369701438,"d":"0.01"},{"v":0.750045877747408,"d":"0.75"},{"v":-0.414949251846314,"d":"-0.41"},1,1,"down","no"]
["ENSG00000227418","PCGEM1","ENST00000454040","NA","NA","NA","NA","PCGEM1, prostate-specific transcript (non-protein coding) [Source:HGNC Symbol;Acc:HGNC:30145]",0,{"v":0.0188320268691589,"d":"0.02"},"-inf","-inf",1,1,"down","no"]
["ENSG00000263812","LINC00908","ENST00000582452;ENST00000583578;ENST00000578613","NA","NA","NA","NA","long intergenic non-protein coding RNA 908 [Source:HGNC Symbol;Acc:HGNC:27599]",{"v":0.0475856376811594,"d":"0.05"},0,"inf","inf",1,1,"up","no"]
["ENSG00000228797","FAM207BP","ENST00000447172","NA","NA","NA","NA","family with sequence similarity 207 member B, pseudogene [Source:HGNC Symbol;Acc:HGNC:39715]",{"v":0.203572,"d":"0.20"},{"v":0.063542,"d":"0.06"},{"v":3.20373925907274,"d":"3.20"},{"v":1.67975673671359,"d":"1.68"},1,1,"up","no"]
["ENSG00000173557","C2orf70","ENST00000409392;ENST00000453368;ENST00000479453","GO:0005634(nucleus);GO:0005634(nucleus)","NA","NA","NA","chromosome 2 open reading frame 70 [Source:HGNC Symbol;Acc:HGNC:27938]",0,{"v":0.0319743250897487,"d":"0.03"},"-inf","-inf",1,1,"down","no"]
["ENSG00000112769","LAMA4","ENST00000368638;ENST00000230538;ENST00000431543","GO:0007155(cell adhesion);GO:0005102(receptor binding);GO:0030334(regulation of cell migration);GO:0030155(regulation of cell adhesion);GO:0045995(regulation of embryonic development);GO:0001568(blood vessel development);GO:0050873(brown fat cell differentiation);GO:0005604(basement membrane);GO:0005605(basal lamina);GO:0005615(extracellular space);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0005578(proteinaceous extracellular matrix);GO:0070062(extracellular exosome);GO:0031012(extracellular matrix);GO:0030198(extracellular matrix organization);GO:0005201(extracellular matrix structural constituent);GO:0005201(extracellular matrix structural constituent)","04151(PI3K-Akt signaling pathway);04512(ECM-receptor interaction);04510(Focal adhesion);05200(Pathways in cancer);05222(Small cell lung cancer);05165(Human papillomavirus infection);05146(Amoebiasis);05145(Toxoplasmosis);05143(African trypanosomiasis);05143(African trypanosomiasis)","K06241","NA","laminin subunit alpha 4 [Source:HGNC Symbol;Acc:HGNC:6484]",{"v":0.0192006254859611,"d":"0.02"},{"v":0.0225539145572354,"d":"0.02"},{"v":0.851321194697062,"d":"0.85"},{"v":-0.232224546324844,"d":"-0.23"},1,1,"down","no"]
["ENSG00000254027","AC009902.2","ENST00000518880","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000128322","IGLL1","ENST00000330377","GO:0016020(membrane);GO:0005576(extracellular region);GO:0006955(immune response);GO:0050900(leukocyte migration);GO:0003823(antigen binding);GO:0034987(immunoglobulin receptor binding);GO:0006910(phagocytosis, recognition);GO:0006911(phagocytosis, engulfment);GO:0006958(complement activation, classical pathway);GO:0042742(defense response to bacterium);GO:0045087(innate immune response);GO:0050853(B cell receptor signaling pathway);GO:0050871(positive regulation of B cell activation);GO:0009897(external side of plasma membrane);GO:0042571(immunoglobulin complex, circulating);GO:0072562(blood microparticle);GO:0070062(extracellular exosome)","05340(Primary immunodeficiency)","K06554","NA","immunoglobulin lambda like polypeptide 1 [Source:HGNC Symbol;Acc:HGNC:5870]",{"v":0.0849122732300885,"d":"0.08"},{"v":0.0504689568584071,"d":"0.05"},{"v":1.68246539091968,"d":"1.68"},{"v":0.750576828245943,"d":"0.75"},1,1,"up","no"]
["ENSG00000257322","AC138123.2","ENST00000550324;ENST00000552451;ENST00000547432","NA","NA","NA","NA",null,0,{"v":0.126555115464995,"d":"0.13"},"-inf","-inf",1,1,"down","no"]
["ENSG00000105290","APLP1","ENST00000537454;ENST00000221891","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0008201(heparin binding);GO:0046914(transition metal ion binding);GO:0048471(perinuclear region of cytoplasm);GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0007155(cell adhesion);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0006915(apoptotic process);GO:0042802(identical protein binding);GO:0006897(endocytosis);GO:0007399(nervous system development);GO:0009887(animal organ morphogenesis);GO:0005604(basement membrane);GO:0031694(alpha-2A adrenergic receptor binding);GO:0031696(alpha-2C adrenergic receptor binding);GO:0030818(negative regulation of cAMP biosynthetic process);GO:0031695(alpha-2B adrenergic receptor binding);GO:0007193(adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway);GO:0071874(cellular response to norepinephrine stimulus);GO:0071874(cellular response to norepinephrine stimulus)","NA","NA","NA","amyloid beta precursor like protein 1 [Source:HGNC Symbol;Acc:HGNC:597]",{"v":0.0385901783369803,"d":"0.04"},{"v":0.0211563170131291,"d":"0.02"},{"v":1.82404991913442,"d":"1.82"},{"v":0.86714521256307,"d":"0.87"},1,1,"up","no"]
["ENSG00000172339","ALG14","ENST00000370205;ENST00000495856","GO:0005634(nucleus);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0006488(dolichol-linked oligosaccharide biosynthetic process);GO:0031965(nuclear membrane);GO:0004577(N-acetylglucosaminyldiphosphodolichol N-acetylglucosaminyltransferase activity);GO:0004577(N-acetylglucosaminyldiphosphodolichol N-acetylglucosaminyltransferase activity)","00510(N-Glycan biosynthesis);00510(N-Glycan biosynthesis)","K07441","EC:2.4.1.141","ALG14, UDP-N-acetylglucosaminyltransferase subunit [Source:HGNC Symbol;Acc:HGNC:28287]",{"v":0.0934162071005917,"d":"0.09"},{"v":0.0549874891518738,"d":"0.05"},{"v":1.69886293303153,"d":"1.70"},{"v":0.764569458282762,"d":"0.76"},1,1,"up","no"]
["ENSG00000275185","AC130324.3","ENST00000614165","NA","NA","NA","NA",null,{"v":0.54753,"d":"0.55"},{"v":0.16667,"d":"0.17"},{"v":3.28511429771405,"d":"3.29"},{"v":1.71594356655266,"d":"1.72"},1,1,"up","no"]
["ENSG00000124092","CTCFL","ENST00000608263;ENST00000608903;ENST00000607923","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0006366(transcription from RNA polymerase II promoter);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0016569(covalent chromatin modification);GO:0003677(DNA binding);GO:0007049(cell cycle);GO:0045893(positive regulation of transcription, DNA-templated);GO:0005515(protein binding);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:0010628(positive regulation of gene expression);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0043565(sequence-specific DNA binding);GO:0042393(histone binding);GO:0044212(transcription regulatory region DNA binding);GO:0001077(transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0043046(DNA methylation involved in gamete generation);GO:0016571(histone methylation);GO:0006349(regulation of gene expression by genetic imprinting);GO:0051569(regulation of histone H3-K4 methylation);GO:0051569(regulation of histone H3-K4 methylation)","NA","NA","NA","CCCTC-binding factor like [Source:HGNC Symbol;Acc:HGNC:16234]",{"v":0.0116116325044803,"d":"0.01"},{"v":0.00795724865591398,"d":"0.01"},{"v":1.45925218710494,"d":"1.46"},{"v":0.545229230511112,"d":"0.55"},1,1,"up","no"]
["ENSG00000267082","AC011472.1","ENST00000588634","NA","NA","NA","NA",null,{"v":1.339121,"d":"1.34"},{"v":0.863307,"d":"0.86"},{"v":1.55115271855782,"d":"1.55"},{"v":0.633340733736718,"d":"0.63"},1,1,"up","no"]
["ENSG00000162377","COA7","ENST00000371538","GO:0005634(nucleus);GO:0005739(mitochondrion);GO:0005758(mitochondrial intermembrane space)","NA","NA","NA","cytochrome c oxidase assembly factor 7 (putative) [Source:HGNC Symbol;Acc:HGNC:25716]",{"v":0.939830704681873,"d":"0.94"},{"v":0.133566990396158,"d":"0.13"},{"v":7.03639950181064,"d":"7.04"},{"v":2.81483739624349,"d":"2.81"},1,1,"up","no"]
["ENSG00000198944","SOWAHA","ENST00000378693","NA","NA","NA","NA","sosondowah ankyrin repeat domain family member A [Source:HGNC Symbol;Acc:HGNC:27033]",{"v":0.016008,"d":"0.02"},{"v":0.01615,"d":"0.02"},{"v":0.991207430340557,"d":"0.99"},{"v":-0.0127410925629085,"d":"-0.01"},1,1,"down","no"]
["ENSG00000174233","ADCY6","ENST00000547260;ENST00000307885","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0035556(intracellular signal transduction);GO:0016829(lyase activity);GO:0005886(plasma membrane);GO:0042995(cell projection);GO:0004016(adenylate cyclase activity);GO:0016849(phosphorus-oxygen lyase activity);GO:0006171(cAMP biosynthetic process);GO:0009190(cyclic nucleotide biosynthetic process);GO:0005515(protein binding);GO:0005929(cilium);GO:0007193(adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway);GO:0031226(intrinsic component of plasma membrane);GO:0019901(protein kinase binding);GO:0010977(negative regulation of neuron projection development);GO:0004383(guanylate cyclase activity);GO:0003091(renal water homeostasis);GO:0006182(cGMP biosynthetic process);GO:0007189(adenylate cyclase-activating G-protein coupled receptor signaling pathway);GO:0007190(activation of adenylate cyclase activity);GO:0007212(dopamine receptor signaling pathway);GO:0034199(activation of protein kinase A activity);GO:0035811(negative regulation of urine volume);GO:0071377(cellular response to glucagon stimulus);GO:0071380(cellular response to prostaglandin E stimulus);GO:0071870(cellular response to catecholamine stimulus);GO:0097746(regulation of blood vessel diameter);GO:1904117(cellular response to vasopressin);GO:1904322(cellular response to forskolin);GO:0008074(guanylate cyclase complex, soluble);GO:0008074(guanylate cyclase complex, soluble)","00230(Purine metabolism);04015(Rap1 signaling pathway);04371(Apelin signaling pathway);04072(Phospholipase D signaling pathway);04024(cAMP signaling pathway);04022(cGMP - PKG signaling pathway);04114(Oocyte meiosis);04540(Gap junction);04611(Platelet activation);04062(Chemokine signaling pathway);04911(Insulin secretion);04923(Regulation of lipolysis in adipocyte);04912(GnRH signaling pathway);04913(Ovarian Steroidogenesis);04915(Estrogen signaling pathway);04914(Progesterone-mediated oocyte maturation);04921(Oxytocin signaling pathway);04926(Relaxin signaling pathway);04918(Thyroid hormone synthesis);04916(Melanogenesis);04924(Renin secretion);04925(Aldosterone synthesis and secretion);04927(Cortisol synthesis and secretion);04261(Adrenergic signaling in cardiomyocytes);04270(Vascular smooth muscle contraction);04970(Salivary secretion);04971(Gastric acid secretion);04972(Pancreatic secretion);04976(Bile secretion);04962(Vasopressin-regulated water reabsorption);04961(Endocrine and other factor-regulated calcium reabsorption);04724(Glutamatergic synapse);04727(GABAergic synapse);04725(Cholinergic synapse);04723(Retrograde endocannabinoid signaling);04742(Taste transduction);04750(Inflammatory mediator regulation of TRP channels);04211(Longevity regulating pathway - mammal);04213(Longevity regulating pathway - multiple species);04713(Circadian entrainment);05200(Pathways in cancer);05032(Morphine addiction);05414(Dilated cardiomyopathy (DCM));05166(HTLV-I infection);01522(Endocrine resistance);01522(Endocrine resistance)","K08046","EC:4.6.1.1","adenylate cyclase 6 [Source:HGNC Symbol;Acc:HGNC:237]",{"v":0.0778931215219976,"d":"0.08"},{"v":0.0574465902497027,"d":"0.06"},{"v":1.3559224522016,"d":"1.36"},{"v":0.439274670344927,"d":"0.44"},1,1,"up","no"]
["ENSG00000181392","SYNE4","ENST00000324444;ENST00000465425","GO:0005634(nucleus);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005515(protein binding);GO:0045198(establishment of epithelial cell apical/basal polarity);GO:0005640(nuclear outer membrane);GO:0031309(integral component of nuclear outer membrane);GO:0031309(integral component of nuclear outer membrane)","NA","NA","NA","spectrin repeat containing nuclear envelope family member 4 [Source:HGNC Symbol;Acc:HGNC:26703]",{"v":0.134265816851266,"d":"0.13"},{"v":0.052879164556962,"d":"0.05"},{"v":2.53910624300112,"d":"2.54"},{"v":1.34432076247028,"d":"1.34"},1,1,"up","no"]
["ENSG00000171385","KCND3","ENST00000369697;ENST00000315987","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0055085(transmembrane transport);GO:0046872(metal ion binding);GO:0005216(ion channel activity);GO:0006811(ion transport);GO:0005244(voltage-gated ion channel activity);GO:0005249(voltage-gated potassium channel activity);GO:0005267(potassium channel activity);GO:0006813(potassium ion transport);GO:0034765(regulation of ion transmembrane transport);GO:0051260(protein homooligomerization);GO:0071805(potassium ion transmembrane transport);GO:0008076(voltage-gated potassium channel complex);GO:0005886(plasma membrane);GO:0042995(cell projection);GO:0005515(protein binding);GO:0030425(dendrite);GO:0042383(sarcolemma);GO:0044325(ion channel binding);GO:0061337(cardiac conduction);GO:0086091(regulation of heart rate by cardiac conduction);GO:0086009(membrane repolarization);GO:0086013(membrane repolarization during cardiac muscle cell action potential);GO:0086008(voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization);GO:1902282(voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization);GO:0071435(potassium ion export);GO:0098915(membrane repolarization during ventricular cardiac muscle cell action potential);GO:0099625(ventricular cardiac muscle cell membrane repolarization);GO:0097623(potassium ion export across plasma membrane);GO:0005250(A-type (transient outward) potassium channel activity);GO:0005250(A-type (transient outward) potassium channel activity)","NA","NA","NA","potassium voltage-gated channel subfamily D member 3 [Source:HGNC Symbol;Acc:HGNC:6239]",{"v":0.160190016024418,"d":"0.16"},{"v":0.0512407417016406,"d":"0.05"},{"v":3.12622360068783,"d":"3.13"},{"v":1.64442096965773,"d":"1.64"},1,1,"up","no"]
["ENSG00000196834","POTEI","ENST00000451531","GO:0005615(extracellular space);GO:0003674(molecular_function);GO:0070062(extracellular exosome);GO:0001895(retina homeostasis)","NA","NA","NA","POTE ankyrin domain family member I [Source:HGNC Symbol;Acc:HGNC:37093]",{"v":0.0223404527979496,"d":"0.02"},{"v":0.00586849209739428,"d":"0.01"},{"v":3.80684721512519,"d":"3.81"},{"v":1.92859666961008,"d":"1.93"},1,1,"up","no"]
["MSTRG.8714","AC012358.2","ENST00000430010","NA","NA","NA","NA",null,{"v":0.138819,"d":"0.14"},{"v":0.140659,"d":"0.14"},{"v":0.986918718318771,"d":"0.99"},{"v":-0.0189968242960594,"d":"-0.02"},1,1,"down","no"]
["ENSG00000018607","ZNF806","ENST00000438300","NA","NA","NA","NA","zinc finger protein 806 [Source:HGNC Symbol;Acc:HGNC:33228]",{"v":0.075283,"d":"0.08"},0,"inf","inf",1,1,"up","no"]
["ENSG00000187486","KCNJ11","ENST00000339994","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005244(voltage-gated ion channel activity);GO:0006811(ion transport);GO:0006813(potassium ion transport);GO:0034765(regulation of ion transmembrane transport);GO:0005242(inward rectifier potassium channel activity);GO:0015272(ATP-activated inward rectifier potassium channel activity);GO:0005886(plasma membrane);GO:0055085(transmembrane transport);GO:0005887(integral component of plasma membrane);GO:0005524(ATP binding);GO:0008022(protein C-terminus binding);GO:0030506(ankyrin binding);GO:0031072(heat shock protein binding);GO:0002931(response to ischemia);GO:0010107(potassium ion import);GO:0032355(response to estradiol);GO:0033574(response to testosterone);GO:0042493(response to drug);GO:0071316(cellular response to nicotine);GO:0071333(cellular response to glucose stimulus);GO:0071356(cellular response to tumor necrosis factor);GO:1905965(positive regulation of protein targeting to plasma membrane);GO:2001259(positive regulation of cation channel activity);GO:0001669(acrosomal vesicle);GO:0005635(nuclear envelope);GO:0005739(mitochondrion);GO:0005768(endosome);GO:0005783(endoplasmic reticulum);GO:0005829(cytosol);GO:0008282(ATP-sensitive potassium channel complex);GO:0014704(intercalated disc);GO:0030315(T-tubule);GO:0030673(axolemma);GO:0042383(sarcolemma);GO:0043025(neuronal cell body);GO:0043209(myelin sheath);GO:0043231(intracellular membrane-bounded organelle);GO:0070852(cell body fiber);GO:0044325(ion channel binding);GO:1903779(regulation of cardiac conduction);GO:0046676(negative regulation of insulin secretion);GO:0042391(regulation of membrane potential);GO:0050796(regulation of insulin secretion);GO:0008076(voltage-gated potassium channel complex);GO:0050877(neurological system process);GO:0030955(potassium ion binding);GO:0006006(glucose metabolic process);GO:0005249(voltage-gated potassium channel activity);GO:0071805(potassium ion transmembrane transport);GO:0033198(response to ATP)","04911(Insulin secretion);04930(Type II diabetes mellitus)","K05004","NA","potassium voltage-gated channel subfamily J member 11 [Source:HGNC Symbol;Acc:HGNC:6257]",{"v":0.0160428061797753,"d":"0.02"},0,"inf","inf",1,1,"up","no"]
["ENSG00000169242","EFNA1","ENST00000497282;ENST00000368407","GO:0005622(intracellular);GO:0010719(negative regulation of epithelial to mesenchymal transition);GO:0016020(membrane);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0031225(anchored component of membrane);GO:0046875(ephrin receptor binding);GO:0048013(ephrin receptor signaling pathway);GO:0070062(extracellular exosome);GO:0005887(integral component of plasma membrane);GO:0007411(axon guidance);GO:0007267(cell-cell signaling);GO:0005102(receptor binding);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0016477(cell migration);GO:0001525(angiogenesis);GO:0033628(regulation of cell adhesion mediated by integrin);GO:0050731(positive regulation of peptidyl-tyrosine phosphorylation);GO:0003183(mitral valve morphogenesis);GO:0050730(regulation of peptidyl-tyrosine phosphorylation);GO:0034446(substrate adhesion-dependent cell spreading);GO:0061098(positive regulation of protein tyrosine kinase activity);GO:0001934(positive regulation of protein phosphorylation);GO:1902961(positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process);GO:0003180(aortic valve morphogenesis);GO:0000165(MAPK cascade);GO:0000187(activation of MAPK activity);GO:0003199(endocardial cushion to mesenchymal transition involved in heart valve formation);GO:0014028(notochord formation);GO:0030182(neuron differentiation);GO:0043535(regulation of blood vessel endothelial cell migration);GO:0045765(regulation of angiogenesis);GO:0050770(regulation of axonogenesis);GO:0050821(protein stabilization);GO:0061002(negative regulation of dendritic spine morphogenesis);GO:0070244(negative regulation of thymocyte apoptotic process);GO:1902004(positive regulation of amyloid-beta formation);GO:1903051(negative regulation of proteolysis involved in cellular protein catabolic process);GO:0046658(anchored component of plasma membrane);GO:0046658(anchored component of plasma membrane)","04014(Ras signaling pathway);04015(Rap1 signaling pathway);04010(MAPK signaling pathway);04151(PI3K-Akt signaling pathway);04360(Axon guidance);04360(Axon guidance)","K05462","NA","ephrin A1 [Source:HGNC Symbol;Acc:HGNC:3221]",{"v":0.239228315872391,"d":"0.24"},{"v":0.168763544702639,"d":"0.17"},{"v":1.41753550089216,"d":"1.42"},{"v":0.503384866609982,"d":"0.50"},1,1,"up","no"]
["MSTRG.2721","KLHL35","ENST00000460787;ENST00000527491;ENST00000376292;ENST00000539798;ENST00000624466","GO:0016567(protein ubiquitination);GO:0005515(protein binding);GO:0004842(ubiquitin-protein transferase activity);GO:0031463(Cul3-RING ubiquitin ligase complex);GO:0031463(Cul3-RING ubiquitin ligase complex)","NA","NA","NA","kelch like family member 35 [Source:HGNC Symbol;Acc:HGNC:26597]",{"v":0.0974983850426503,"d":"0.10"},{"v":0.00766296528466574,"d":"0.01"},{"v":12.7233233377363,"d":"12.72"},{"v":3.66940364732141,"d":"3.67"},1,1,"up","no"]
["ENSG00000275418","AC104971.4","ENST00000622763","NA","NA","NA","NA",null,0,0,1,0,1,1,"no","no"]
["ENSG00000274102","OR4M2","ENST00000614722","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0004930(G-protein coupled receptor activity);GO:0007186(G-protein coupled receptor signaling pathway);GO:0005886(plasma membrane);GO:0004871(signal transducer activity);GO:0007165(signal transduction);GO:0004984(olfactory receptor activity);GO:0007608(sensory perception of smell);GO:0050896(response to stimulus);GO:0050911(detection of chemical stimulus involved in sensory perception of smell);GO:0004888(transmembrane signaling receptor activity);GO:0050907(detection of chemical stimulus involved in sensory perception)","04740(Olfactory transduction)","K04257","NA","olfactory receptor family 4 subfamily M member 2 [Source:HGNC Symbol;Acc:HGNC:15373]",{"v":0.090434,"d":"0.09"},{"v":0.054496,"d":"0.05"},{"v":1.65946124486201,"d":"1.66"},{"v":0.730714937040034,"d":"0.73"},1,1,"up","no"]
["ENSG00000278959","AC006378.2","ENST00000623178","NA","NA","NA","NA",null,{"v":0.325795,"d":"0.33"},0,"inf","inf",1,1,"up","no"]
["ENSG00000163873","GRIK3","ENST00000373091","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005216(ion channel activity);GO:0006811(ion transport);GO:0034220(ion transmembrane transport);GO:0005886(plasma membrane);GO:0035725(sodium ion transmembrane transport);GO:0071805(potassium ion transmembrane transport);GO:0030054(cell junction);GO:0045202(synapse);GO:0045211(postsynaptic membrane);GO:0004872(receptor activity);GO:0030425(dendrite);GO:0004970(ionotropic glutamate receptor activity);GO:0005234(extracellular-glutamate-gated ion channel activity);GO:0035235(ionotropic glutamate receptor signaling pathway);GO:0060079(excitatory postsynaptic potential);GO:0005887(integral component of plasma membrane);GO:0030424(axon);GO:0043204(perikaryon);GO:0007196(adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway);GO:0008066(glutamate receptor activity);GO:0007216(G-protein coupled glutamate receptor signaling pathway);GO:0042391(regulation of membrane potential);GO:0032839(dendrite cytoplasm);GO:0015276(ligand-gated ion channel activity);GO:0015277(kainate selective glutamate receptor activity);GO:0043195(terminal bouton);GO:0007215(glutamate receptor signaling pathway);GO:0001640(adenylate cyclase inhibiting G-protein coupled glutamate receptor activity);GO:0001664(G-protein coupled receptor binding);GO:0051967(negative regulation of synaptic transmission, glutamatergic)","04080(Neuroactive ligand-receptor interaction);04724(Glutamatergic synapse)","K05203","NA","glutamate ionotropic receptor kainate type subunit 3 [Source:HGNC Symbol;Acc:HGNC:4581]",{"v":0.0243992490357037,"d":"0.02"},{"v":0.019326235881713,"d":"0.02"},{"v":1.26249359601323,"d":"1.26"},{"v":0.336276069826102,"d":"0.34"},1,1,"up","no"]
["ENSG00000250742","LINC02381","ENST00000508564","NA","NA","NA","NA","long intergenic non-protein coding RNA 2381 [Source:HGNC Symbol;Acc:HGNC:53304]",{"v":0.0178017411255411,"d":"0.02"},{"v":0.108658893073593,"d":"0.11"},{"v":0.163831423475704,"d":"0.16"},{"v":-2.60971599709876,"d":"-2.61"},1,1,"down","no"]
["ENSG00000103460","TOX3","ENST00000566696","GO:0005634(nucleus);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0042803(protein homodimerization activity);GO:0006915(apoptotic process);GO:0045893(positive regulation of transcription, DNA-templated);GO:0005515(protein binding);GO:0003682(chromatin binding);GO:0042981(regulation of apoptotic process);GO:0043524(negative regulation of neuron apoptotic process);GO:0034056(estrogen response element binding);GO:0051219(phosphoprotein binding)","NA","NA","NA","TOX high mobility group box family member 3 [Source:HGNC Symbol;Acc:HGNC:11972]",0,{"v":0.0181374263565891,"d":"0.02"},"-inf","-inf",1,1,"down","no"]
["ENSG00000253806","AC108002.2","ENST00000519782","NA","NA","NA","NA",null,0,{"v":0.156809,"d":"0.16"},"-inf","-inf",1,1,"down","no"]
["ENSG00000064835","POU1F1","ENST00000350375;ENST00000344265","GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0005634(nucleus);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0043565(sequence-specific DNA binding);GO:0045893(positive regulation of transcription, DNA-templated);GO:0006366(transcription from RNA polymerase II promoter);GO:0000981(RNA polymerase II transcription factor activity, sequence-specific DNA binding);GO:0001102(RNA polymerase II activating transcription factor binding);GO:0008285(negative regulation of cell proliferation);GO:0001085(RNA polymerase II transcription factor binding);GO:0001105(RNA polymerase II transcription coactivator activity);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:0001077(transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0003682(chromatin binding);GO:0003714(transcription corepressor activity);GO:0008134(transcription factor binding);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0001708(cell fate specification);GO:0008284(positive regulation of cell proliferation);GO:0008340(determination of adult lifespan);GO:0021983(pituitary gland development);GO:0021984(adenohypophysis development);GO:0030183(B cell differentiation);GO:0032962(positive regulation of inositol trisphosphate biosynthetic process);GO:0040018(positive regulation of multicellular organism growth);GO:0043567(regulation of insulin-like growth factor receptor signaling pathway);GO:0051169(nuclear transport);GO:0060126(somatotropin secreting cell differentiation);GO:0060133(somatotropin secreting cell development);GO:0005667(transcription factor complex);GO:0005667(transcription factor complex)","NA","NA","NA","POU class 1 homeobox 1 [Source:HGNC Symbol;Acc:HGNC:9210]",0,{"v":0.029078707456979,"d":"0.03"},"-inf","-inf",1,1,"down","no"]
["ENSG00000158560","DYNC1I1","ENST00000324972;ENST00000630942;ENST00000447467","GO:0006810(transport);GO:0005737(cytoplasm);GO:0005694(chromosome);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0005874(microtubule);GO:0003774(motor activity);GO:0007018(microtubule-based movement);GO:0005634(nucleus);GO:0005868(cytoplasmic dynein complex);GO:0000922(spindle pole);GO:0000775(chromosome, centromeric region);GO:0000776(kinetochore);GO:0000777(condensed chromosome kinetochore);GO:0030286(dynein complex);GO:0005829(cytosol);GO:0055037(recycling endosome);GO:0007062(sister chromatid cohesion);GO:0019886(antigen processing and presentation of exogenous peptide antigen via MHC class II);GO:0031982(vesicle);GO:0006888(ER to Golgi vesicle-mediated transport);GO:0008574(ATP-dependent microtubule motor activity, plus-end-directed);GO:0003777(microtubule motor activity);GO:0008017(microtubule binding);GO:0030507(spectrin binding);GO:0045503(dynein light chain binding);GO:0045504(dynein heavy chain binding);GO:0047496(vesicle transport along microtubule);GO:2000582(positive regulation of ATP-dependent microtubule motor activity, plus-end-directed);GO:0036464(cytoplasmic ribonucleoprotein granule);GO:0048471(perinuclear region of cytoplasm);GO:0048471(perinuclear region of cytoplasm)","04145(Phagosome);04962(Vasopressin-regulated water reabsorption);05132(Salmonella infection);05132(Salmonella infection)","K10415","NA","dynein cytoplasmic 1 intermediate chain 1 [Source:HGNC Symbol;Acc:HGNC:2963]",{"v":0.065455915061296,"d":"0.07"},{"v":0.0255689192206655,"d":"0.03"},{"v":2.55997973541223,"d":"2.56"},{"v":1.3561323900159,"d":"1.36"},1,1,"up","no"]
["ENSG00000230062","ANKRD66","ENST00000445060","GO:0005622(intracellular)","NA","NA","NA","ankyrin repeat domain 66 [Source:HGNC Symbol;Acc:HGNC:44669]",0,0,1,0,1,1,"no","no"]
["ENSG00000163687","DNASE1L3","ENST00000463694;ENST00000486455;ENST00000483681;ENST00000394549","GO:0005634(nucleus);GO:0016787(hydrolase activity);GO:0005783(endoplasmic reticulum);GO:0005576(extracellular region);GO:0006915(apoptotic process);GO:0004519(endonuclease activity);GO:0004518(nuclease activity);GO:0004536(deoxyribonuclease activity);GO:0006308(DNA catabolic process);GO:0003677(DNA binding);GO:0006259(DNA metabolic process);GO:0012501(programmed cell death);GO:0005509(calcium ion binding);GO:0006309(apoptotic DNA fragmentation);GO:0090305(nucleic acid phosphodiester bond hydrolysis);GO:0004520(endodeoxyribonuclease activity);GO:0010623(programmed cell death involved in cell development);GO:0010623(programmed cell death involved in cell development)","NA","NA","NA","deoxyribonuclease 1 like 3 [Source:HGNC Symbol;Acc:HGNC:2959]",{"v":0.228638742693774,"d":"0.23"},{"v":0.0835279313850063,"d":"0.08"},{"v":2.73727289665425,"d":"2.74"},{"v":1.45273927358614,"d":"1.45"},1,1,"up","no"]
["ENSG00000214491","SEC14L6","ENST00000402034","GO:0016021(integral component of membrane);GO:0006810(transport);GO:0005215(transporter activity);GO:0005622(intracellular)","NA","NA","NA","SEC14 like lipid binding 6 [Source:HGNC Symbol;Acc:HGNC:40047]",{"v":0.010309,"d":"0.01"},{"v":0.010255,"d":"0.01"},{"v":1.00526572403706,"d":"1.01"},{"v":0.00757690247785621,"d":"0.01"},1,1,"up","no"]
["ENSG00000275411","MIR6882","ENST00000619233","NA","NA","NA","NA","microRNA 6882 [Source:HGNC Symbol;Acc:HGNC:49928]",{"v":0.002596,"d":"0.00"},{"v":0.308768,"d":"0.31"},{"v":0.00840760700590735,"d":"0.01"},{"v":-6.89408904922013,"d":"-6.89"},1,1,"down","no"]
["ENSG00000151418","ATP6V1G3","ENST00000367382","GO:0006810(transport);GO:0005829(cytosol);GO:0015992(proton transport);GO:0006811(ion transport);GO:0005886(plasma membrane);GO:1902600(hydrogen ion transmembrane transport);GO:0016820(hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances);GO:0016471(vacuolar proton-transporting V-type ATPase complex);GO:0034220(ion transmembrane transport);GO:0008286(insulin receptor signaling pathway);GO:0033572(transferrin transport);GO:0090383(phagosome acidification);GO:0051117(ATPase binding);GO:0008553(hydrogen-exporting ATPase activity, phosphorylative mechanism)","00190(Oxidative phosphorylation);04150(mTOR signaling pathway);04145(Phagosome);04966(Collecting duct acid secretion);04721(Synaptic vesicle cycle);05323(Rheumatoid arthritis);05110(Vibrio cholerae infection);05120(Epithelial cell signaling in Helicobacter pylori infection)","K02152","NA","ATPase H+ transporting V1 subunit G3 [Source:HGNC Symbol;Acc:HGNC:18265]",{"v":0.0586173928571429,"d":"0.06"},0,"inf","inf",1,1,"up","no"]
["MSTRG.234","ELOA-AS1","ENST00000427796;ENST00000447961","NA","NA","NA","NA","ELOA antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:50582]",{"v":0.180326752783964,"d":"0.18"},{"v":0.144659971046771,"d":"0.14"},{"v":1.24655598559232,"d":"1.25"},{"v":0.31794767891653,"d":"0.32"},1,1,"up","no"]
["ENSG00000161652","IZUMO2","ENST00000600293;ENST00000594854","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005634(nucleus);GO:0005634(nucleus)","NA","NA","NA","IZUMO family member 2 [Source:HGNC Symbol;Acc:HGNC:28518]",{"v":0.0122467213765718,"d":"0.01"},{"v":0.00593836135009927,"d":"0.01"},{"v":2.06230652777084,"d":"2.06"},{"v":1.04425878141042,"d":"1.04"},1,1,"up","no"]
["ENSG00000284677","AL031985.4","ENST00000642138","NA","NA","NA","NA",null,0,{"v":0.106807,"d":"0.11"},"-inf","-inf",1,1,"down","no"]
["ENSG00000222047","C10orf55","ENST00000409178","NA","NA","NA","NA","chromosome 10 open reading frame 55 [Source:HGNC Symbol;Acc:HGNC:31008]",{"v":0.017725946300716,"d":"0.02"},{"v":0.0394113170246619,"d":"0.04"},{"v":0.449767925533264,"d":"0.45"},{"v":-1.15274731354937,"d":"-1.15"},1,1,"down","no"]
["ENSG00000283294","AP005212.5","ENST00000577614","NA","NA","NA","NA",null,{"v":0.028423,"d":"0.03"},0,"inf","inf",1,1,"up","no"]
["ENSG00000215102","TERF1P4","ENST00000399580","NA","NA","NA","NA","telomeric repeat binding factor 1 pseudogene 4 [Source:HGNC Symbol;Acc:HGNC:38500]",{"v":0.015982,"d":"0.02"},0,"inf","inf",1,1,"up","no"]
["ENSG00000233467","U40455.1","ENST00000411473","NA","NA","NA","NA",null,0,{"v":0.038679,"d":"0.04"},"-inf","-inf",1,1,"down","no"]
["MSTRG.6300","AC005696.2","ENST00000610120","NA","NA","NA","NA",null,{"v":0.159187,"d":"0.16"},{"v":0.417757,"d":"0.42"},{"v":0.38105166400563,"d":"0.38"},{"v":-1.39194147944795,"d":"-1.39"},1,1,"down","no"]
["MSTRG.1234","RN7SL230P","ENST00000580835","NA","NA","NA","NA","RNA, 7SL, cytoplasmic 230, pseudogene [Source:HGNC Symbol;Acc:HGNC:46246]",0,{"v":0.301148,"d":"0.30"},"-inf","-inf",1,1,"down","no"]
["ENSG00000167494","NOS2P2","ENST00000639528","NA","NA","NA","NA","nitric oxide synthase 2 pseudogene 2 [Source:HGNC Symbol;Acc:HGNC:7874]",0,{"v":0.00577792553191489,"d":"0.01"},"-inf","-inf",1,1,"down","no"]
["ENSG00000146250","PRSS35","ENST00000369700","GO:0005576(extracellular region);GO:0005739(mitochondrion)","NA","NA","NA","protease, serine 35 [Source:HGNC Symbol;Acc:HGNC:21387]",0,{"v":0.03721,"d":"0.04"},"-inf","-inf",1,1,"down","no"]
["ENSG00000271538","LINC02427","ENST00000605270","NA","NA","NA","NA","long intergenic non-protein coding RNA 2427 [Source:HGNC Symbol;Acc:HGNC:53358]",{"v":0.0852698003194888,"d":"0.09"},{"v":0.0347406134185303,"d":"0.03"},{"v":2.4544701986755,"d":"2.45"},{"v":1.29541165010829,"d":"1.30"},1,1,"up","no"]
["ENSG00000112562","SMOC2","ENST00000354536","GO:0046872(metal ion binding);GO:0005509(calcium ion binding);GO:0007165(signal transduction);GO:0005576(extracellular region);GO:0005578(proteinaceous extracellular matrix);GO:0005604(basement membrane);GO:0005539(glycosaminoglycan binding);GO:0008201(heparin binding);GO:0010811(positive regulation of cell-substrate adhesion);GO:0030198(extracellular matrix organization);GO:0005614(interstitial matrix);GO:0016020(membrane);GO:0016021(integral component of membrane)","NA","NA","NA","SPARC related modular calcium binding 2 [Source:HGNC Symbol;Acc:HGNC:20323]",{"v":0.02866953125,"d":"0.03"},0,"inf","inf",1,1,"up","no"]
["MSTRG.12842","LINC01149","ENST00000430364","NA","NA","NA","NA","long intergenic non-protein coding RNA 1149 [Source:HGNC Symbol;Acc:HGNC:39757]",{"v":0.045776,"d":"0.05"},0,"inf","inf",1,1,"up","no"]
["ENSG00000228157","AC007952.2","ENST00000574724;ENST00000399091","NA","NA","NA","NA",null,{"v":0.00475792056829189,"d":"0.00"},{"v":0.0405123083629319,"d":"0.04"},{"v":0.117443827828022,"d":"0.12"},{"v":-3.08995719929704,"d":"-3.09"},1,1,"down","no"]
["ENSG00000229503","AC092155.2","ENST00000454675","NA","NA","NA","NA",null,{"v":0.567798,"d":"0.57"},0,"inf","inf",1,1,"up","no"]
["ENSG00000219435","CATSPERZ","ENST00000535981;ENST00000539943","GO:0016020(membrane);GO:0005886(plasma membrane);GO:0042995(cell projection);GO:0030154(cell differentiation);GO:0007283(spermatogenesis);GO:0005737(cytoplasm);GO:0030317(flagellated sperm motility);GO:0048240(sperm capacitation);GO:0097228(sperm principal piece);GO:0036128(CatSper complex);GO:0007140(male meiotic nuclear division);GO:0007140(male meiotic nuclear division)","NA","NA","NA","catsper channel auxiliary subunit zeta [Source:HGNC Symbol;Acc:HGNC:19231]",0,{"v":0.0205958540892193,"d":"0.02"},"-inf","-inf",1,1,"down","no"]

{"sheet":"Table 4","index":3,"n_rows":129,"n_cols":6,"rows_kept":129}
["gene_name","FPKM.T3","FPKM.T4","qval","regulation","significant"]
["FP671120.3",1.28,79.97,0,"up","yes"]
["S1PR1",0.43,22.82,0,"up","yes"]
["FP236383.3;FP236383.2",1.57,65.29,0,"up","yes"]
["IFI27",0.53,16,0,"up","yes"]
["MSL2",0.27,7.89,0,"up","yes"]
["TRGV8",0.43,10.93,0,"up","yes"]
["TMEM250",0.31,6.71,0,"up","yes"]
["MALAT1",2.87,53.3,0,"up","yes"]
["ZNF574",0.21,3.29,0,"up","yes"]
["MLLT11",0.35,5.01,0,"up","yes"]
["MTPN",1.2,14.94,0,"up","yes"]
["TUBB2A",1.36,14.67,0,"up","yes"]
["CBX5",0.34,3.41,0,"up","yes"]
["MT-TN",11.43,108.6,0,"up","yes"]
["BLCAP",0.39,3.55,0,"up","yes"]
["ZNF224",0.24,2.11,0,"up","yes"]
["RHOG",5.66,46.62,0,"up","yes"]
["CCR6",0.2,1.7,0,"up","yes"]
["AC092070.2",0.18,1.53,0,"up","yes"]
["CEBPB",2.24,17.17,0.01,"up","yes"]
["FBXO34",0.35,2.68,0.01,"up","yes"]
["MZB1",0.85,6.41,0.01,"up","yes"]
["IGKV1D-39",2.67,20.27,0.01,"up","yes"]
["RABIF",0.32,2.38,0.01,"up","yes"]
["EXOC8",0.4,2.77,0.01,"up","yes"]
["NPIPB13",0.21,1.55,0.01,"up","yes"]
["MED28",0.55,3.68,0.01,"up","yes"]
["CD300E",2.25,14.44,0.02,"up","yes"]
["ZNF320",0.17,1.12,0.02,"up","yes"]
["TMEM109",3.29,20.98,0.02,"up","yes"]
["LINC01278",0.46,2.98,0.02,"up","yes"]
["ZNF180",0.15,1.02,0.02,"up","yes"]
["FCN1",0.24,1.58,0.02,"up","yes"]
["AHDC1",0.32,2.04,0.02,"up","yes"]
["TP53RK",0.58,3.63,0.02,"up","yes"]
["TRBV20-1",2.37,14.45,0.03,"up","yes"]
["GIMAP2",1.76,10.23,0.03,"up","yes"]
["HCP5;MICA",2.61,14.94,0.03,"up","yes"]
["MKI67",0.32,1.86,0.03,"up","yes"]
["ARPC5L",0.76,4.34,0.03,"up","yes"]
["SLC35B2",0.93,5.33,0.03,"up","yes"]
["SOCS7",0.23,1.27,0.03,"up","yes"]
["ZBTB14",0.65,3.62,0.03,"up","yes"]
["ORAI1",2.89,15.85,0.04,"up","yes"]
["CD93",3.13,16.8,0.04,"up","yes"]
["CHRM3-AS2",0.3,1.67,0.04,"up","yes"]
["ZNF707",0.19,1.06,0.04,"up","yes"]
["S1PR5",2.25,11.54,0.05,"up","yes"]
["TRAF1",1.4,7.12,0.05,"up","yes"]
["CD52",68.32,1.11,0,"down","yes"]
["KCNJ15;DSCR8",12.3,0.21,0,"down","yes"]
["CXCR4",80.33,1.64,0,"down","yes"]
["PLEKHF2",9.8,0.24,0,"down","yes"]
["LRG1;PLIN5;AC011498.4",8.95,0.41,0,"down","yes"]
["B3GNT8",9.21,0.41,0,"down","yes"]
["AC113404.3",18.68,0.92,0,"down","yes"]
["AL034397.3",25.87,1.55,0,"down","yes"]
["KIAA0040",32.92,2.11,0,"down","yes"]
["MRVI1",12.28,0.82,0,"down","yes"]
["RBAK",1.83,0.13,0,"down","yes"]
["GNA12",5.37,0.39,0,"down","yes"]
["ZBTB2",4.65,0.34,0,"down","yes"]
["AC068888.1",2.57,0.19,0,"down","yes"]
["ISCA1",9.09,0.71,0,"down","yes"]
["C2orf88",7.79,0.68,0,"down","yes"]
["BASP1",85.6,7.95,0,"down","yes"]
["TP53INP2",8.47,0.79,0,"down","yes"]
["SPATA2",2.49,0.22,0,"down","yes"]
["AC239868.2",2.35,0.21,0,"down","yes"]
["TLR5",2.53,0.23,0,"down","yes"]
["DUSP1",99.44,10.19,0,"down","yes"]
["LRRC4",12.89,1.34,0,"down","yes"]
["GABARAPL1",14.48,1.53,0,"down","yes"]
["CD14",53.11,5.77,0,"down","yes"]
["COTL1",110.98,12.3,0,"down","yes"]
["ADGRG3",32.11,3.62,0,"down","yes"]
["ZNF182",2.42,0.26,0,"down","yes"]
["PDK4",2.1,0.22,0,"down","yes"]
["MANSC1",3.63,0.41,0,"down","yes"]
["GNG7",3.07,0.35,0,"down","yes"]
["EME2",1.12,0.13,0,"down","yes"]
["TNFRSF10C",99.53,12.17,0,"down","yes"]
["NEK7",12.12,1.58,0.01,"down","yes"]
["CLEC4E;AC092746.1",10.33,1.38,0.01,"down","yes"]
["ZNF160",1.77,0.23,0.01,"down","yes"]
["TLR2",20.92,2.92,0.01,"down","yes"]
["MRPS14",2.53,0.34,0.01,"down","yes"]
["LINC01506",9.08,1.16,0.01,"down","yes"]
["VAMP5",11.31,1.58,0.01,"down","yes"]
["CTDSPL",2.71,0.39,0.02,"down","yes"]
["NOV",7.95,1.16,0.02,"down","yes"]
["TFEC",2.67,0.39,0.02,"down","yes"]
["ZNF148",3.05,0.46,0.02,"down","yes"]
["FOPNL",3.66,0.53,0.02,"down","yes"]
["GDE1",10.39,1.61,0.02,"down","yes"]
["PPCS",10.36,1.62,0.02,"down","yes"]
["RAB3D;TMEM205;AC011472.2",21.7,3.48,0.02,"down","yes"]
["IL1RAP",8.12,1.31,0.02,"down","yes"]
["GPR34",2.71,0.4,0.02,"down","yes"]
["ANGPT1",1.48,0.23,0.02,"down","yes"]
["ZBTB3",1.36,0.2,0.02,"down","yes"]
["AP003068.2",11.54,1.9,0.03,"down","yes"]
["CHST2",4.71,0.78,0.03,"down","yes"]
["KLHL21",5.96,0.99,0.03,"down","yes"]
["IFNAR1",11.96,2.01,0.03,"down","yes"]
["SLC45A4",8.32,1.4,0.03,"down","yes"]
["FUT7;NPDC1",5.38,0.91,0.03,"down","yes"]
["MPZL1",3.46,0.58,0.03,"down","yes"]
["MGAM",22.75,3.9,0.03,"down","yes"]
["EMC6",5.32,0.81,0.03,"down","yes"]
["TAGLN2",436.33,75.25,0.03,"down","yes"]
["ZNF45",1.36,0.22,0.03,"down","yes"]
["CCNJL",6.29,1.09,0.03,"down","yes"]
["CDKN1A",9.98,1.73,0.03,"down","yes"]
["PROK2",29.52,5.21,0.04,"down","yes"]
["TCN1",4.16,0.71,0.04,"down","yes"]
["PTENP1",1.15,0.19,0.04,"down","yes"]
["MARVELD1",4.09,0.71,0.04,"down","yes"]
["RAB9A",3.77,0.65,0.04,"down","yes"]
["MSRB1",92.18,16.72,0.04,"down","yes"]
["MAP1LC3B",11.08,2.01,0.04,"down","yes"]
["COPZ1",10.2,1.84,0.04,"down","yes"]
["CCDC97",13.93,2.54,0.04,"down","yes"]
["CCR3",7.64,1.4,0.04,"down","yes"]
["UBE2D1",8.42,1.54,0.04,"down","yes"]
["CMTM2",21.51,3.96,0.05,"down","yes"]
["CYP51A1",1.21,0.22,0.05,"down","yes"]
["LUCAT1;AC123595.2",2.71,0.51,0.05,"down","yes"]

{"sheet":"Table 5","index":4,"n_rows":5,"n_cols":8,"rows_kept":5}
[null,"gene_name","FPKM.T1","FPKM.T2","FPKM.T3","FPKM.T4","regulation","significant"]
[1,"S1PR1",1.06,18.52,0.43,22.82,"up","yes"]
[2,"AL034397.3",21.41,1.59,25.87,1.55,"down","yes"]
[3,"GNA12",4.55,0.88,5.37,0.39,"down","yes"]
[4,"MAP1LC3B",14.84,3.24,11.08,2.01,"down","yes"]

{"sheet":"Table 6","index":5,"n_rows":114144,"n_cols":24,"rows_kept":2250,"cut":true,"bounds":{"rows_first":1000,"rows_last":250,"rows_between":1000,"halvings":1}}
["t_id","class_code","chr","strand","start","end","t_name","num_exons","length","gene_id","gene_name","GO","KEGG","KO_ENTRY","EC","Description","FPKM.T2","FPKM.T1","fc","log2(fc)","pval","qval","regulation","significant"]
[10600,"j","chr1","-",150572483,150579662,"MSTRG.917.5",4,5843,"MSTRG.917","MCL1","NA","NA","NA","NA","NA",{"v":79.339363,"d":"79.34"},{"v":0.207301,"d":"0.21"},{"v":382.725423418121,"d":"382.73"},{"v":8.58016592830661,"d":"8.58"},{"v":1.83315422779816e-20,"d":"0.00"},{"v":3.627445585967e-16,"d":"0.00"},"up","yes"]
[83824,0,"chr17","+",42998477,43002932,"ENST00000589913",4,697,"MSTRG.6848","RPL27","GO:0003723(RNA binding);GO:0005634(nucleus);GO:0016020(membrane);GO:0006412(translation);GO:0030529(intracellular ribonucleoprotein complex);GO:0005622(intracellular);GO:0003735(structural constituent of ribosome);GO:0005840(ribosome);GO:0005925(focal adhesion);GO:0006364(rRNA processing);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0031012(extracellular matrix);GO:0006413(translational initiation);GO:0000184(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay);GO:0019083(viral transcription);GO:0006614(SRP-dependent cotranslational protein targeting to membrane);GO:0022625(cytosolic large ribosomal subunit)","03010(Ribosome)","NA","NA","ribosomal protein L27 [Source:HGNC Symbol;Acc:HGNC:10328]",{"v":1.829624,"d":"1.83"},{"v":350.630829,"d":"350.63"},{"v":0.00521809221744161,"d":"0.01"},{"v":-7.58226184405787,"d":"-7.58"},{"v":1.10550596455143e-18,"d":"0.00"},{"v":1.09378760132719e-14,"d":"0.00"},"down","yes"]
[50161,"j","chr13","-",46125920,46203222,"MSTRG.3990.3",20,4094,"MSTRG.3990","LCP1","NA","NA","NA","NA","NA",{"v":0.536439,"d":"0.54"},{"v":87.880333,"d":"87.88"},{"v":0.00610419853552444,"d":"0.01"},{"v":-7.35598239890534,"d":"-7.36"},{"v":4.2822154290809e-18,"d":"0.00"},{"v":2.82454929702176e-14,"d":"0.00"},"down","yes"]
[3370,0,"chr1","-",28147166,28177188,"ENST00000373857",2,4491,"MSTRG.321","PTAFR","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0004930(G-protein coupled receptor activity);GO:0007186(G-protein coupled receptor signaling pathway);GO:0005886(plasma membrane);GO:0004871(signal transducer activity);GO:0007165(signal transduction);GO:0006935(chemotaxis);GO:0035589(G-protein coupled purinergic nucleotide receptor signaling pathway);GO:0048015(phosphatidylinositol-mediated signaling);GO:0005887(integral component of plasma membrane);GO:0043312(neutrophil degranulation);GO:0070821(tertiary granule membrane);GO:0006954(inflammatory response);GO:0006955(immune response);GO:0030667(secretory granule membrane);GO:0005543(phospholipid binding);GO:0060333(interferon-gamma-mediated signaling pathway);GO:0045028(G-protein coupled purinergic nucleotide receptor activity);GO:0031663(lipopolysaccharide-mediated signaling pathway);GO:0004992(platelet activating factor receptor activity);GO:0001530(lipopolysaccharide binding);GO:0001875(lipopolysaccharide receptor activity);GO:0051019(mitogen-activated protein kinase binding);GO:0001816(cytokine production);GO:0002693(positive regulation of cellular extravasation);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0007567(parturition);GO:0009609(response to symbiotic bacterium);GO:0010863(positive regulation of phospholipase C activity);GO:0032496(response to lipopolysaccharide);GO:0032760(positive regulation of tumor necrosis factor production);GO:0032959(inositol trisphosphate biosynthetic process);GO:0043315(positive regulation of neutrophil degranulation);GO:0045056(transcytosis);GO:0045410(positive regulation of interleukin-6 biosynthetic process);GO:0045727(positive regulation of translation);GO:0045776(negative regulation of blood pressure);GO:0045907(positive regulation of vasoconstriction);GO:0045987(positive regulation of smooth muscle contraction);GO:0046683(response to organophosphorus);GO:0048661(positive regulation of smooth muscle cell proliferation);GO:0060732(positive regulation of inositol phosphate biosynthetic process);GO:0071258(cellular response to gravity);GO:0071320(cellular response to cAMP);GO:0071398(cellular response to fatty acid);GO:0071548(response to dexamethasone);GO:0097755(positive regulation of blood vessel diameter);GO:1902943(positive regulation of voltage-gated chloride channel activity);GO:1903039(positive regulation of leukocyte cell-cell adhesion);GO:1903238(positive regulation of leukocyte tethering or rolling);GO:1904058(positive regulation of sensory perception of pain);GO:1904300(positive regulation of transcytosis);GO:1904303(positive regulation of maternal process involved in parturition);GO:1904306(positive regulation of gastro-intestinal system smooth muscle contraction);GO:1904316(response to 2-O-acetyl-1-O-hexadecyl-sn-glycero-3-phosphocholine);GO:1904317(cellular response to 2-O-acetyl-1-O-hexadecyl-sn-glycero-3-phosphocholine)","04020(Calcium signaling pathway);04080(Neuroactive ligand-receptor interaction);05150(Staphylococcus aureus infection)","K04279","NA","platelet activating factor receptor [Source:HGNC Symbol;Acc:HGNC:9582]",{"v":0.265618,"d":"0.27"},{"v":39.891457,"d":"39.89"},{"v":6.65851838903753E-3,"d":"0.01"},{"v":-7.23058309093661,"d":"-7.23"},{"v":1.41898458672644E-17,"d":"0.00"},{"v":7.0197167505357e-14,"d":"0.00"},"down","yes"]
[112126,"j","chr2","-",88857160,89143159,"MSTRG.8934.23",5,960,"MSTRG.8934","AC244205.1","NA","NA","NA","NA","NA",{"v":0.810684,"d":"0.81"},{"v":96.02002,"d":"96.02"},{"v":0.00844286431100514,"d":"0.01"},{"v":-6.88805175655422,"d":"-6.89"},{"v":1.76663874212505E-16,"d":"0.00"},{"v":6.99164948583411e-13,"d":"0.00"},"down","yes"]
[135536,0,"chr3","-",46201709,46208396,"ENST00000296140",2,2731,"MSTRG.10876","CCR1","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0004930(G-protein coupled receptor activity);GO:0007186(G-protein coupled receptor signaling pathway);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0004871(signal transducer activity);GO:0007165(signal transduction);GO:0006955(immune response);GO:0006816(calcium ion transport);GO:0004950(chemokine receptor activity);GO:0016493(C-C chemokine receptor activity);GO:0006935(chemotaxis);GO:0006954(inflammatory response);GO:0070098(chemokine-mediated signaling pathway);GO:0090026(positive regulation of monocyte chemotaxis);GO:0004435(phosphatidylinositol phospholipase C activity);GO:0006887(exocytosis);GO:0005887(integral component of plasma membrane);GO:0010629(negative regulation of gene expression);GO:0070374(positive regulation of ERK1 and ERK2 cascade);GO:0007155(cell adhesion);GO:0007166(cell surface receptor signaling pathway);GO:0009611(response to wounding);GO:0030335(positive regulation of cell migration);GO:0007204(positive regulation of cytosolic calcium ion concentration);GO:0002407(dendritic cell chemotaxis);GO:0007267(cell-cell signaling);GO:0045672(positive regulation of osteoclast differentiation);GO:0051928(positive regulation of calcium ion transport);GO:0019221(cytokine-mediated signaling pathway);GO:0009897(external side of plasma membrane);GO:0006874(cellular calcium ion homeostasis);GO:0007187(G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger);GO:0030502(negative regulation of bone mineralization);GO:0019957(C-C chemokine binding);GO:0035717(chemokine (C-C motif) ligand 7 binding);GO:0071791(chemokine (C-C motif) ligand 5 binding)","04060(Cytokine-cytokine receptor interaction);04062(Chemokine signaling pathway);05167(Kaposi's sarcoma-associated herpesvirus infection)","K04176","NA","C-C motif chemokine receptor 1 [Source:HGNC Symbol;Acc:HGNC:1602]",{"v":45.869339,"d":"45.87"},{"v":0.311315,"d":"0.31"},{"v":147.340600356552,"d":"147.34"},{"v":7.20301121595406,"d":"7.20"},{"v":2.91485733726828e-16,"d":"0.00"},{"v":9.61319949831078E-13,"d":"0.00"},"up","yes"]
[38828,"j","chr12","-",10371395,10409769,"MSTRG.3171.1",13,3265,"MSTRG.3171","KLRC4-KLRK1","NA","NA","NA","NA","NA",{"v":0.324778,"d":"0.32"},{"v":23.605186,"d":"23.61"},{"v":0.0137587562326346,"d":"0.01"},{"v":-6.1835061309347,"d":"-6.18"},{"v":1.83355357860432e-14,"d":"0.00"},{"v":5.18319403048889e-11,"d":"0.00"},"down","yes"]
[9090,"j","chr1","+",110871180,110899960,"MSTRG.776.1",9,1615,"MSTRG.776","CD53","NA","NA","NA","NA","NA",{"v":1.248683,"d":"1.25"},{"v":84.018875,"d":"84.02"},{"v":0.0148619342975016,"d":"0.01"},{"v":-6.0722342932922,"d":"-6.07"},{"v":2.78934152914602e-14,"d":"0.00"},{"v":6.42471935856246e-11,"d":"0.00"},"down","yes"]
[186084,"j","chr8","-",100916694,100953382,"MSTRG.14503.3",8,5359,"MSTRG.14503","YWHAZ","NA","NA","NA","NA","NA",{"v":24.553171,"d":"24.55"},{"v":0.274247,"d":"0.27"},{"v":89.5294059734473,"d":"89.53"},{"v":6.48428970893169,"d":"6.48"},{"v":2.92209794961907e-14,"d":"0.00"},{"v":6.42471935856246e-11,"d":"0.00"},"up","yes"]
[4678,0,"chr1","-",40072710,40097247,"ENST00000641471",10,2368,"MSTRG.463","PPT1","GO:0005615(extracellular space);GO:0044257(cellular protein catabolic process);GO:0005764(lysosome);GO:0043025(neuronal cell body);GO:0030424(axon);GO:0007601(visual perception);GO:0030425(dendrite);GO:0008474(palmitoyl-(protein) hydrolase activity);GO:0002084(protein depalmitoylation);GO:0007040(lysosome organization);GO:0007269(neurotransmitter secretion);GO:0007625(grooming behavior);GO:0008306(associative learning);GO:0008344(adult locomotory behavior);GO:0032429(regulation of phospholipase A2 activity);GO:0044265(cellular macromolecule catabolic process);GO:0008021(synaptic vesicle);GO:0043005(neuron projection);GO:0045202(synapse);GO:0098599(palmitoyl hydrolase activity);GO:0005634(nucleus);GO:0016020(membrane);GO:0015031(protein transport);GO:0016787(hydrolase activity);GO:0005794(Golgi apparatus);GO:0016042(lipid catabolic process);GO:0005829(cytosol);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0007399(nervous system development);GO:0045121(membrane raft);GO:0050896(response to stimulus);GO:0048666(neuron development);GO:0070062(extracellular exosome);GO:0043524(negative regulation of neuron apoptotic process);GO:0016290(palmitoyl-CoA hydrolase activity);GO:0043066(negative regulation of apoptotic process);GO:0030308(negative regulation of cell growth);GO:0048260(positive regulation of receptor-mediated endocytosis);GO:0007268(chemical synaptic transmission);GO:0007420(brain development);GO:0043202(lysosomal lumen);GO:0046949(fatty-acyl-CoA biosynthetic process);GO:0030163(protein catabolic process);GO:0031579(membrane raft organization);GO:0007042(lysosomal lumen acidification);GO:0030149(sphingolipid catabolic process);GO:0050803(regulation of synapse structure or activity);GO:0006898(receptor-mediated endocytosis);GO:0006907(pinocytosis);GO:0048549(positive regulation of pinocytosis);GO:0051181(cofactor transport);GO:0051186(cofactor metabolic process)","00062(Fatty acid elongation);04142(Lysosome)","NA","NA","palmitoyl-protein thioesterase 1 [Source:HGNC Symbol;Acc:HGNC:9325]",{"v":0.35818,"d":"0.36"},{"v":23.11417,"d":"23.11"},{"v":0.0154961220757656,"d":"0.02"},{"v":-6.01194896537451,"d":"-6.01"},{"v":7.25704829814041e-14,"d":"0.00"},{"v":1.43602471723602E-10,"d":"0.00"},"down","yes"]
[67292,0,"chr16","+",172944,173463,"ENST00000484216",2,403,"MSTRG.5480","HBA2","GO:0010942(positive regulation of cell death);GO:0006810(transport);GO:0016020(membrane);GO:0046872(metal ion binding);GO:0005506(iron ion binding);GO:0005515(protein binding);GO:0022627(cytosolic small ribosomal subunit);GO:0005615(extracellular space);GO:0020037(heme binding);GO:0098869(cellular oxidant detoxification);GO:0006898(receptor-mediated endocytosis);GO:0005576(extracellular region);GO:0005344(oxygen transporter activity);GO:0019825(oxygen binding);GO:0015671(oxygen transport);GO:0005833(hemoglobin complex);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0072562(blood microparticle);GO:0015701(bicarbonate transport);GO:0042542(response to hydrogen peroxide);GO:0031838(haptoglobin-hemoglobin complex);GO:0071682(endocytic vesicle lumen);GO:0004601(peroxidase activity);GO:0042744(hydrogen peroxide catabolic process);GO:0031720(haptoglobin binding);GO:0051291(protein heterooligomerization)","05144(Malaria);05143(African trypanosomiasis)","NA","NA","hemoglobin subunit alpha 2 [Source:HGNC Symbol;Acc:HGNC:4824]",{"v":432.353973,"d":"432.35"},{"v":6.00913,"d":"6.01"},{"v":71.9495123254115,"d":"71.95"},{"v":6.16891300328317,"d":"6.17"},{"v":2.02268220479542E-13,"d":"0.00"},{"v":3.63862140622652e-10,"d":"0.00"},"up","yes"]
[87474,0,"chr17","+",70169535,70180048,"ENST00000243457",2,5392,"MSTRG.7156","KCNJ2","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005244(voltage-gated ion channel activity);GO:0006811(ion transport);GO:0006813(potassium ion transport);GO:0034765(regulation of ion transmembrane transport);GO:0005242(inward rectifier potassium channel activity);GO:0005886(plasma membrane);GO:0005887(integral component of plasma membrane);GO:0061337(cardiac conduction);GO:0051289(protein homotetramerization);GO:0060306(regulation of membrane repolarization);GO:0090076(relaxation of skeletal muscle);GO:0031224(intrinsic component of membrane);GO:0008076(voltage-gated potassium channel complex);GO:0086002(cardiac muscle cell action potential involved in contraction);GO:0086091(regulation of heart rate by cardiac conduction);GO:0010107(potassium ion import);GO:0086012(membrane depolarization during cardiac muscle cell action potential);GO:0030007(cellular potassium ion homeostasis);GO:0055119(relaxation of cardiac muscle);GO:0086013(membrane repolarization during cardiac muscle cell action potential);GO:0086008(voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization);GO:0071805(potassium ion transmembrane transport);GO:0086011(membrane repolarization during action potential);GO:0005546(phosphatidylinositol-4,5-bisphosphate binding);GO:0015467(G-protein activated inward rectifier potassium channel activity);GO:0014861(regulation of skeletal muscle contraction via regulation of action potential);GO:0060075(regulation of resting membrane potential);GO:0042802(identical protein binding);GO:0015693(magnesium ion transport);GO:0071260(cellular response to mechanical stimulus);GO:0086001(cardiac muscle cell action potential);GO:0086004(regulation of cardiac muscle cell contraction);GO:1901381(positive regulation of potassium ion transmembrane transport);GO:0005790(smooth endoplasmic reticulum);GO:0005791(rough endoplasmic reticulum);GO:0005794(Golgi apparatus);GO:0014704(intercalated disc);GO:0030315(T-tubule);GO:0030425(dendrite);GO:0043025(neuronal cell body);GO:0043197(dendritic spine)","04921(Oxytocin signaling pathway);04924(Renin secretion);04971(Gastric acid secretion);04725(Cholinergic synapse)","K04996","NA","potassium voltage-gated channel subfamily J member 2 [Source:HGNC Symbol;Acc:HGNC:6263]",{"v":0.160771,"d":"0.16"},{"v":8.494132,"d":"8.49"},{"v":0.0189273018125925,"d":"0.02"},{"v":-5.72338742791635,"d":"-5.72"},{"v":4.71717152822429e-13,"d":"0.00"},{"v":7.77861585004186e-10,"d":"0.00"},"down","yes"]
[116548,0,"chr2","-",174559572,174634579,"ENST00000392547",8,4587,"MSTRG.9248","WIPF1","GO:0005737(cytoplasm);GO:0003779(actin binding);GO:0015629(actin cytoskeleton);GO:0008154(actin polymerization or depolymerization);GO:0005856(cytoskeleton);GO:0042995(cell projection);GO:0005515(protein binding);GO:0031410(cytoplasmic vesicle);GO:0038096(Fc-gamma receptor signaling pathway involved in phagocytosis);GO:0030048(actin filament-based movement);GO:0051707(response to other organism);GO:0005884(actin filament);GO:0005829(cytosol);GO:0017124(SH3 domain binding);GO:0001726(ruffle);GO:0006461(protein complex assembly);GO:0005522(profilin binding)","04144(Endocytosis)","K19475","NA","WAS/WASL interacting protein family member 1 [Source:HGNC Symbol;Acc:HGNC:12736]",{"v":44.505737,"d":"44.51"},{"v":0.711874,"d":"0.71"},{"v":62.5191213613645,"d":"62.52"},{"v":5.96622559784891,"d":"5.97"},{"v":7.28499305672026E-13,"d":"0.00"},{"v":1.10888802004908e-09,"d":"0.00"},"up","yes"]
[62005,0,"chr15","+",44711927,44717704,"ENST00000559907",4,499,"MSTRG.5036","B2M","GO:0016020(membrane);GO:0005794(Golgi apparatus);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0006955(immune response);GO:0005615(extracellular space);GO:0002376(immune system process);GO:0005925(focal adhesion);GO:0050776(regulation of immune response);GO:0042802(identical protein binding);GO:0002474(antigen processing and presentation of peptide antigen via MHC class I);GO:0042612(MHC class I protein complex);GO:0070062(extracellular exosome);GO:0044267(cellular protein metabolic process);GO:0001895(retina homeostasis);GO:0002479(antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent);GO:0045087(innate immune response);GO:0043312(neutrophil degranulation);GO:0030670(phagocytic vesicle membrane);GO:0009986(cell surface);GO:1990712(HFE-transferrin receptor complex);GO:0005788(endoplasmic reticulum lumen);GO:0035580(specific granule lumen);GO:1904724(tertiary granule lumen);GO:0000139(Golgi membrane);GO:0048260(positive regulation of receptor-mediated endocytosis);GO:0060333(interferon-gamma-mediated signaling pathway);GO:0012507(ER to Golgi transport vesicle membrane);GO:0032092(positive regulation of protein binding);GO:0050690(regulation of defense response to virus by virus);GO:0031901(early endosome membrane);GO:0002480(antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent);GO:0055038(recycling endosome membrane);GO:0002726(positive regulation of T cell cytokine production);GO:0019885(antigen processing and presentation of endogenous peptide antigen via MHC class I);GO:0055072(iron ion homeostasis);GO:0071281(cellular response to iron ion);GO:0001916(positive regulation of T cell mediated cytotoxicity);GO:0002237(response to molecule of bacterial origin);GO:0002481(antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent);GO:0006826(iron ion transport);GO:0010977(negative regulation of neuron projection development);GO:0033077(T cell differentiation in thymus);GO:0033216(ferric iron import);GO:0042026(protein refolding);GO:0042493(response to drug);GO:0045646(regulation of erythrocyte differentiation);GO:0046686(response to cadmium ion);GO:0071283(cellular response to iron(III) ion);GO:1900121(negative regulation of receptor binding);GO:1900122(positive regulation of receptor binding);GO:1904434(positive regulation of ferrous iron binding);GO:1904437(positive regulation of transferrin receptor binding);GO:1904440(positive regulation of ferrous iron import across plasma membrane);GO:0009897(external side of plasma membrane);GO:0031905(early endosome lumen)","04612(Antigen processing and presentation)","NA","NA","beta-2-microglobulin [Source:HGNC Symbol;Acc:HGNC:914]",{"v":3.810944,"d":"3.81"},{"v":179.049911,"d":"179.05"},{"v":0.0212842552041257,"d":"0.02"},{"v":-5.55406958272366,"d":"-5.55"},{"v":9.51063616375221e-13,"d":"0.00"},{"v":1.34426048863092e-09,"d":"0.00"},"down","yes"]
[103561,0,"chr19","-",48615393,48619127,"ENST00000550973",7,1111,"MSTRG.8290","RPL18","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0006412(translation);GO:0005783(endoplasmic reticulum);GO:0005730(nucleolus);GO:0005829(cytosol);GO:0030529(intracellular ribonucleoprotein complex);GO:0005622(intracellular);GO:0003735(structural constituent of ribosome);GO:0005840(ribosome);GO:0005925(focal adhesion);GO:0006413(translational initiation);GO:0003723(RNA binding);GO:0006364(rRNA processing);GO:0000184(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay);GO:0019083(viral transcription);GO:0006614(SRP-dependent cotranslational protein targeting to membrane);GO:0022625(cytosolic large ribosomal subunit)","03010(Ribosome)","NA","NA","ribosomal protein L18 [Source:HGNC Symbol;Acc:HGNC:10310]",{"v":2.043635,"d":"2.04"},{"v":87.671089,"d":"87.67"},{"v":0.0233102499730555,"d":"0.02"},{"v":-5.42289171413875,"d":"-5.42"},{"v":2.18230298842665e-12,"d":"0.00"},{"v":2.87889410233244e-09,"d":"0.00"},"down","yes"]
[164364,"j","chr6","-",31353817,31357196,"MSTRG.12847.20",7,2185,"MSTRG.12847","HLA-B","NA","NA","NA","NA","NA",{"v":1.109548,"d":"1.11"},{"v":45.146935,"d":"45.15"},{"v":0.0245763748967676,"d":"0.02"},{"v":-5.34658406105166,"d":"-5.35"},{"v":3.3395212918795e-12,"d":"0.00"},{"v":4.13015295773197e-09,"d":"0.00"},"down","yes"]
[1337,"j","chr1","+",9651672,9729182,"MSTRG.139.2",25,5702,"MSTRG.139","PIK3CD","NA","NA","NA","NA","NA",{"v":42.873322,"d":"42.87"},{"v":0.815869,"d":"0.82"},{"v":52.549272003226,"d":"52.55"},{"v":5.71559887268832,"d":"5.72"},{"v":3.62677952638755E-12,"d":"0.00"},{"v":4.22157136871511e-09,"d":"0.00"},"up","yes"]
[198227,"j","chrX","-",72255679,72277018,"MSTRG.15362.2",8,1385,"MSTRG.15362","RPS4X","NA","NA","NA","NA","NA",{"v":1.20195,"d":"1.20"},{"v":45.187019,"d":"45.19"},{"v":0.0265994532633365,"d":"0.03"},{"v":-5.23245959752117,"d":"-5.23"},{"v":8.65205026300663e-12,"d":"0.00"},{"v":9.15798995835463e-09,"d":"0.00"},"down","yes"]
[56570,"j","chr14","-",73274834,73465941,"MSTRG.4515.5",12,4291,"MSTRG.4515","NUMB","NA","NA","NA","NA","NA",{"v":0.322001,"d":"0.32"},{"v":12.139792,"d":"12.14"},{"v":0.0265244248006885,"d":"0.03"},{"v":-5.23653472407076,"d":"-5.24"},{"v":8.79329943444198e-12,"d":"0.00"},{"v":9.15798995835463e-09,"d":"0.00"},"down","yes"]
[103466,0,"chr19","+",48255675,48258199,"ENST00000602172",2,1969,"MSTRG.8286","CARD8-AS1","NA","NA","NA","NA","CARD8 antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:51408]",{"v":0.410835,"d":"0.41"},{"v":15.56928,"d":"15.57"},{"v":0.0263875400789247,"d":"0.03"},{"v":-5.24399932495182,"d":"-5.24"},{"v":1.24805862720985e-11,"d":"0.00"},{"v":1.23482920576143e-08,"d":"0.00"},"down","yes"]
[165905,0,"chr6","-",41275204,41286719,"ENST00000244709",4,1690,"MSTRG.13025","TREM1","GO:0005622(intracellular);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005886(plasma membrane);GO:0005576(extracellular region);GO:0050776(regulation of immune response);GO:0050900(leukocyte migration);GO:0045087(innate immune response);GO:0004872(receptor activity);GO:0097110(scaffold protein binding);GO:0035556(intracellular signal transduction);GO:0006959(humoral immune response);GO:0002374(cytokine secretion involved in immune response);GO:0016477(cell migration);GO:0030593(neutrophil chemotaxis);GO:0042107(cytokine metabolic process);GO:0050755(chemokine metabolic process);GO:0070945(neutrophil mediated killing of gram-negative bacterium);GO:0072672(neutrophil extravasation)","NA","NA","NA","triggering receptor expressed on myeloid cells 1 [Source:HGNC Symbol;Acc:HGNC:17760]",{"v":21.55357,"d":"21.55"},{"v":0.455091,"d":"0.46"},{"v":47.3610113142207,"d":"47.36"},{"v":5.56562798249344,"d":"5.57"},{"v":1.84344023131474e-11,"d":"0.00"},{"v":1.73704739510743E-8,"d":"0.00"},"up","yes"]
[40207,"j","chr12","+",31959419,31996117,"MSTRG.3283.4",7,8516,"MSTRG.3283","KIAA1551","NA","NA","NA","NA","NA",{"v":10.156001,"d":"10.16"},{"v":0.228499,"d":"0.23"},{"v":44.4465883876953,"d":"44.45"},{"v":5.47400078042057,"d":"5.47"},{"v":2.16615803866707e-11,"d":"0.00"},{"v":1.84879330635215E-8,"d":"0.00"},"up","yes"]
[145229,"j","chr4","+",1721421,1745061,"MSTRG.11494.1",15,3612,"MSTRG.11494","TACC3","NA","NA","NA","NA","NA",{"v":17.591267,"d":"17.59"},{"v":0.390896,"d":"0.39"},{"v":45.0024226392698,"d":"45.00"},{"v":5.49193076378703,"d":"5.49"},{"v":2.23644766455818e-11,"d":"0.00"},{"v":1.84879330635215E-8,"d":"0.00"},"up","yes"]
[118979,0,"chr2","-",218162845,218166995,"ENST00000295683",2,2488,"MSTRG.9412","CXCR1","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0004930(G-protein coupled receptor activity);GO:0007186(G-protein coupled receptor signaling pathway);GO:0005886(plasma membrane);GO:0004871(signal transducer activity);GO:0007165(signal transduction);GO:0006935(chemotaxis);GO:0070098(chemokine-mediated signaling pathway);GO:0016494(C-X-C chemokine receptor activity);GO:0043312(neutrophil degranulation);GO:0019959(interleukin-8 binding);GO:0006954(inflammatory response);GO:0030667(secretory granule membrane);GO:0004950(chemokine receptor activity);GO:0002407(dendritic cell chemotaxis);GO:0031623(receptor internalization);GO:0007166(cell surface receptor signaling pathway);GO:0004918(interleukin-8 receptor activity);GO:0038112(interleukin-8-mediated signaling pathway)","04072(Phospholipase D signaling pathway);04060(Cytokine-cytokine receptor interaction);04144(Endocytosis);04062(Chemokine signaling pathway);05120(Epithelial cell signaling in Helicobacter pylori infection)","K04175","NA","C-X-C motif chemokine receptor 1 [Source:HGNC Symbol;Acc:HGNC:6026]",{"v":4.634412,"d":"4.63"},{"v":150.870682,"d":"150.87"},{"v":0.0307177772285804,"d":"0.03"},{"v":-5.0247823649046,"d":"-5.02"},{"v":2.29339693872988e-11,"d":"0.00"},{"v":1.84879330635215E-8,"d":"0.00"},"down","yes"]
[139636,0,"chr3","-",121663203,121749767,"ENST00000614479",21,11115,"ENSG00000173230","GOLGB1","GO:0003723(RNA binding);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005794(Golgi apparatus);GO:0006355(regulation of transcription, DNA-templated);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0043565(sequence-specific DNA binding);GO:0005515(protein binding);GO:0000139(Golgi membrane);GO:0006888(ER to Golgi vesicle-mediated transport);GO:0005793(endoplasmic reticulum-Golgi intermediate compartment);GO:0005795(Golgi stack);GO:0007030(Golgi organization);GO:1905793(protein localization to pericentriolar material);GO:0005801(cis-Golgi network)","NA","NA","NA","golgin B1 [Source:HGNC Symbol;Acc:HGNC:4429]",{"v":4.90446,"d":"4.90"},{"v":0.108931,"d":"0.11"},{"v":45.023547016001,"d":"45.02"},{"v":5.49260781362561,"d":"5.49"},{"v":2.33575058918555e-11,"d":"0.00"},{"v":1.84879330635215E-8,"d":"0.00"},"up","yes"]
[132564,"j","chr22","-",50523554,50530051,"MSTRG.10610.2",9,2188,"MSTRG.10610","TYMP","NA","NA","NA","NA","NA",{"v":1.187094,"d":"1.19"},{"v":37.066086,"d":"37.07"},{"v":0.0320264189750167,"d":"0.03"},{"v":-4.96459369718226,"d":"-4.96"},{"v":4.21882676727256e-11,"d":"0.00"},{"v":3.1538237169252E-8,"d":"0.00"},"down","yes"]
[11832,0,"chr1","+",155689083,155738526,"ENST00000343043",13,1649,"MSTRG.1064","DAP3","GO:0003723(RNA binding);GO:0000166(nucleotide binding);GO:0005654(nucleoplasm);GO:0005739(mitochondrion);GO:0030529(intracellular ribonucleoprotein complex);GO:0005840(ribosome);GO:0005525(GTP binding);GO:0015935(small ribosomal subunit);GO:0006915(apoptotic process);GO:0005515(protein binding);GO:0005761(mitochondrial ribosome);GO:0003735(structural constituent of ribosome);GO:0005763(mitochondrial small ribosomal subunit);GO:0005743(mitochondrial inner membrane);GO:0070125(mitochondrial translational elongation);GO:0070126(mitochondrial translational termination);GO:0097190(apoptotic signaling pathway)","NA","NA","NA","death associated protein 3 [Source:HGNC Symbol;Acc:HGNC:2673]",{"v":0.686315,"d":"0.69"},{"v":22.158461,"d":"22.16"},{"v":0.0309730445629775,"d":"0.03"},{"v":-5.01284298693576,"d":"-5.01"},{"v":4.30327675141401E-11,"d":"0.00"},{"v":3.1538237169252E-8,"d":"0.00"},"down","yes"]
[111645,0,"chr2","-",85318027,85328251,"ENST00000398263",5,6138,"MSTRG.8860","TGOLN2","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005794(Golgi apparatus);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0005802(trans-Golgi network);GO:0044267(cellular protein metabolic process);GO:0061024(membrane organization);GO:0005768(endosome);GO:0043687(post-translational protein modification);GO:0006895(Golgi to endosome transport);GO:0005788(endoplasmic reticulum lumen);GO:0030133(transport vesicle);GO:0030140(trans-Golgi network transport vesicle);GO:0030665(clathrin-coated vesicle membrane)","NA","NA","NA","trans-golgi network protein 2 [Source:HGNC Symbol;Acc:HGNC:15450]",{"v":27.335714,"d":"27.34"},{"v":0.691414,"d":"0.69"},{"v":39.5359567495017,"d":"39.54"},{"v":5.30509343242627,"d":"5.31"},{"v":5.54413698476647E-11,"d":"0.00"},{"v":3.91812080909139e-08,"d":"0.00"},"up","yes"]
[12971,"j","chr1","-",161541756,161550911,"MSTRG.1160.5",6,2461,"MSTRG.1160","FCGR3A","NA","NA","NA","NA","NA",{"v":0.415757,"d":"0.42"},{"v":12.464366,"d":"12.46"},{"v":0.0333556476117598,"d":"0.03"},{"v":-4.9059251377601,"d":"-4.91"},{"v":9.06717958052592e-11,"d":"0.00"},{"v":6.07516562693623e-08,"d":"0.00"},"down","yes"]
[124731,"j","chr20","-",53567073,53609847,"MSTRG.9839.2",8,5968,"MSTRG.9839","ZNF217","NA","NA","NA","NA","NA",{"v":7.01129,"d":"7.01"},{"v":0.1794,"d":"0.18"},{"v":39.081884057971,"d":"39.08"},{"v":5.28842811325745,"d":"5.29"},{"v":9.2103784519955e-11,"d":"0.00"},{"v":6.07516562693623e-08,"d":"0.00"},"up","yes"]
[104753,0,"chr19","-",51745172,51751909,"ENST00000304748",2,1930,"MSTRG.8382","FPR1","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0004930(G-protein coupled receptor activity);GO:0007186(G-protein coupled receptor signaling pathway);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0004871(signal transducer activity);GO:0007165(signal transduction);GO:0004982(N-formyl peptide receptor activity);GO:0006935(chemotaxis);GO:0060326(cell chemotaxis);GO:0005887(integral component of plasma membrane);GO:0006954(inflammatory response);GO:0043312(neutrophil degranulation);GO:0005622(intracellular);GO:0030667(secretory granule membrane);GO:0035577(azurophil granule membrane);GO:0101003(ficolin-1-rich granule membrane);GO:0007188(adenylate cyclase-modulating G-protein coupled receptor signaling pathway);GO:0004875(complement receptor activity);GO:0002430(complement receptor mediated signaling pathway);GO:0007204(positive regulation of cytosolic calcium ion concentration);GO:0050900(leukocyte migration);GO:0007263(nitric oxide mediated signal transduction);GO:0000187(activation of MAPK activity);GO:0005124(scavenger receptor binding);GO:0050786(RAGE receptor binding);GO:0007200(phospholipase C-activating G-protein coupled receptor signaling pathway)","04015(Rap1 signaling pathway);04080(Neuroactive ligand-receptor interaction);05150(Staphylococcus aureus infection)","K04172","NA","formyl peptide receptor 1 [Source:HGNC Symbol;Acc:HGNC:3826]",{"v":11.565171,"d":"11.57"},{"v":317.727081,"d":"317.73"},{"v":0.0363997017931248,"d":"0.04"},{"v":-4.77992955867335,"d":"-4.78"},{"v":1.07920543568511E-10,"d":"0.00"},{"v":6.78333682937528e-08,"d":"0.00"},"down","yes"]
[122527,0,"chr20","-",23626706,23637945,"ENST00000398411",4,3286,"MSTRG.9624","CST3","GO:0005615(extracellular space);GO:0010951(negative regulation of endopeptidase activity);GO:0005576(extracellular region);GO:0004869(cysteine-type endopeptidase inhibitor activity);GO:0030414(peptidase inhibitor activity);GO:0010466(negative regulation of peptidase activity);GO:0042802(identical protein binding);GO:0002020(protease binding);GO:0001654(eye development);GO:0001666(response to hypoxia);GO:0001775(cell activation);GO:0006915(apoptotic process);GO:0006979(response to oxidative stress);GO:0007420(brain development);GO:0007431(salivary gland development);GO:0007566(embryo implantation);GO:0008284(positive regulation of cell proliferation);GO:0008584(male gonad development);GO:0009636(response to toxic substance);GO:0009743(response to carbohydrate);GO:0010035(response to inorganic substance);GO:0014070(response to organic cyclic compound);GO:0031667(response to nutrient levels);GO:0032355(response to estradiol);GO:0034599(cellular response to oxidative stress);GO:0042493(response to drug);GO:0042747(circadian sleep/wake cycle, REM sleep);GO:0043067(regulation of programmed cell death);GO:0045740(positive regulation of DNA replication);GO:0048678(response to axon injury);GO:0060009(Sertoli cell development);GO:0060548(negative regulation of cell death);GO:0070301(cellular response to hydrogen peroxide);GO:0005604(basement membrane);GO:0005737(cytoplasm);GO:0005764(lysosome);GO:0005771(multivesicular body);GO:0005783(endoplasmic reticulum);GO:0030424(axon);GO:0031965(nuclear membrane);GO:0031982(vesicle);GO:0042995(cell projection);GO:0043025(neuronal cell body);GO:0043292(contractile fiber);GO:0048471(perinuclear region of cytoplasm);GO:0005515(protein binding);GO:0070062(extracellular exosome);GO:0044267(cellular protein metabolic process);GO:0043687(post-translational protein modification);GO:0043312(neutrophil degranulation);GO:1904813(ficolin-1-rich granule lumen);GO:0005788(endoplasmic reticulum lumen);GO:1904724(tertiary granule lumen);GO:0097435(supramolecular fiber organization);GO:2000117(negative regulation of cysteine-type endopeptidase activity);GO:0001540(amyloid-beta binding);GO:0004866(endopeptidase inhibitor activity);GO:0006952(defense response);GO:0010711(negative regulation of collagen catabolic process);GO:0010716(negative regulation of extracellular matrix disassembly);GO:0034103(regulation of tissue remodeling);GO:0045861(negative regulation of proteolysis);GO:0060311(negative regulation of elastin catabolic process);GO:0060313(negative regulation of blood vessel remodeling)","04970(Salivary secretion)","K13899","NA","cystatin C [Source:HGNC Symbol;Acc:HGNC:2475]",{"v":12.102365,"d":"12.10"},{"v":0.314236,"d":"0.31"},{"v":38.5136171539862,"d":"38.51"},{"v":5.26729672062042,"d":"5.27"},{"v":1.09696168657777E-10,"d":"0.00"},{"v":6.78333682937528e-08,"d":"0.00"},"up","yes"]
[187984,0,"chr8","-",143579728,143597413,"ENST00000526838",8,926,"MSTRG.14619","EEF1D","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0006412(translation);GO:0005829(cytosol);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0001650(fibrillar center);GO:0005783(endoplasmic reticulum);GO:0005515(protein binding);GO:0004871(signal transducer activity);GO:0003746(translation elongation factor activity);GO:0006414(translational elongation);GO:0005853(eukaryotic translation elongation factor 1 complex);GO:0007165(signal transduction);GO:0045296(cadherin binding);GO:0043123(positive regulation of I-kappaB kinase/NF-kappaB signaling);GO:0008135(translation factor activity, RNA binding);GO:0071479(cellular response to ionizing radiation)","05168(Herpes simplex infection)","K15410","NA","eukaryotic translation elongation factor 1 delta [Source:HGNC Symbol;Acc:HGNC:3211]",{"v":1.223871,"d":"1.22"},{"v":35.583294,"d":"35.58"},{"v":0.0343945391902166,"d":"0.03"},{"v":-4.86167666288738,"d":"-4.86"},{"v":1.14326990717099E-10,"d":"0.00"},{"v":6.85546209790895e-08,"d":"0.00"},"down","yes"]
[70200,0,"chr16","-",18782968,18790362,"ENST00000576008",6,589,"MSTRG.5711","RPS15A","GO:0003723(RNA binding);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0006412(translation);GO:0030529(intracellular ribonucleoprotein complex);GO:0003735(structural constituent of ribosome);GO:0005840(ribosome);GO:0022627(cytosolic small ribosomal subunit);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0009615(response to virus);GO:0031012(extracellular matrix);GO:0005739(mitochondrion);GO:0005515(protein binding);GO:0008284(positive regulation of cell proliferation);GO:0006413(translational initiation);GO:0006364(rRNA processing);GO:0045787(positive regulation of cell cycle);GO:0000184(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay);GO:0019083(viral transcription);GO:0006614(SRP-dependent cotranslational protein targeting to membrane)","03010(Ribosome)","NA","NA","ribosomal protein S15a [Source:HGNC Symbol;Acc:HGNC:10389]",{"v":8.419853,"d":"8.42"},{"v":222.04567,"d":"222.05"},{"v":0.0379194649461077,"d":"0.04"},{"v":-4.72091758221163,"d":"-4.72"},{"v":1.79048381186278E-10,"d":"0.00"},{"v":1.00730535527996E-7,"d":"0.00"},"down","yes"]
[85745,0,"chr17","+",51166564,51171744,"ENST00000393190",4,866,"MSTRG.7032","NME2","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0042995(cell projection);GO:0005515(protein binding);GO:0007229(integrin-mediated signaling pathway);GO:0004550(nucleoside diphosphate kinase activity);GO:0006165(nucleoside diphosphate phosphorylation);GO:0006183(GTP biosynthetic process);GO:0006228(UTP biosynthetic process);GO:0006241(CTP biosynthetic process);GO:0009117(nucleotide metabolic process);GO:0005576(extracellular region);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0005829(cytosol);GO:0030027(lamellipodium);GO:0070062(extracellular exosome);GO:0071944(cell periphery);GO:0043312(neutrophil degranulation);GO:0001726(ruffle);GO:0034774(secretory granule lumen);GO:1904813(ficolin-1-rich granule lumen);GO:0015949(nucleobase-containing small molecule interconversion);GO:0009142(nucleoside triphosphate biosynthetic process);GO:0050679(positive regulation of epithelial cell proliferation);GO:0043066(negative regulation of apoptotic process);GO:0007155(cell adhesion);GO:0004673(protein histidine kinase activity);GO:0018106(peptidyl-histidine phosphorylation);GO:0045618(positive regulation of keratinocyte differentiation);GO:0045682(regulation of epidermis development);GO:0004674(protein serine/threonine kinase activity);GO:0005504(fatty acid binding);GO:0008144(drug binding);GO:0019215(intermediate filament binding);GO:0019899(enzyme binding);GO:0002762(negative regulation of myeloid leukocyte differentiation);GO:0010976(positive regulation of neuron projection development);GO:0030819(positive regulation of cAMP biosynthetic process);GO:0034599(cellular response to oxidative stress);GO:0046777(protein autophosphorylation);GO:0051259(protein oligomerization);GO:0060416(response to growth hormone);GO:0071333(cellular response to glucose stimulus);GO:0071398(cellular response to fatty acid);GO:0005882(intermediate filament);GO:0031966(mitochondrial membrane);GO:0048471(perinuclear region of cytoplasm)","00230(Purine metabolism);00240(Pyrimidine metabolism);00983(Drug metabolism - other enzymes)","K00940","EC:2.7.4.6","NME/NM23 nucleoside diphosphate kinase 2 [Source:HGNC Symbol;Acc:HGNC:7850]",{"v":1.348344,"d":"1.35"},{"v":37.485886,"d":"37.49"},{"v":0.0359693779146637,"d":"0.04"},{"v":-4.79708698129366,"d":"-4.80"},{"v":1.81131766934257e-10,"d":"0.00"},{"v":1.00730535527996E-7,"d":"0.00"},"down","yes"]
[146944,0,"chr4","-",40424338,40629864,"ENST00000295971",7,4056,"MSTRG.11588","RBM47","GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0005634(nucleus);GO:0002244(hematopoietic progenitor cell differentiation);GO:0016554(cytidine to uridine editing)","NA","NA","NA","RNA binding motif protein 47 [Source:HGNC Symbol;Acc:HGNC:30358]",{"v":17.833012,"d":"17.83"},{"v":0.501901,"d":"0.50"},{"v":35.5309353836713,"d":"35.53"},{"v":5.15100376429448,"d":"5.15"},{"v":1.83257493380223e-10,"d":"0.00"},{"v":1.00730535527996E-7,"d":"0.00"},"up","yes"]
[168240,0,"chr6","+",108560866,108684768,"ENST00000406360",3,7341,"MSTRG.13199","FOXO3","GO:0043065(positive regulation of apoptotic process);GO:0005737(cytoplasm);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0006355(regulation of transcription, DNA-templated);GO:0006366(transcription from RNA polymerase II promoter);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0031490(chromatin DNA binding);GO:0005829(cytosol);GO:0043565(sequence-specific DNA binding);GO:0005515(protein binding);GO:0006915(apoptotic process);GO:0045893(positive regulation of transcription, DNA-templated);GO:0001047(core promoter binding);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0019901(protein kinase binding);GO:0006417(regulation of translation);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0009653(anatomical structure morphogenesis);GO:0034599(cellular response to oxidative stress);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0033209(tumor necrosis factor-mediated signaling pathway);GO:0001227(transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding);GO:0008013(beta-catenin binding);GO:0043525(positive regulation of neuron apoptotic process);GO:0045648(positive regulation of erythrocyte differentiation);GO:0001221(transcription cofactor binding);GO:0001228(transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding);GO:0001542(ovulation from ovarian follicle);GO:0001544(initiation of primordial ovarian follicle growth);GO:0001547(antral ovarian follicle growth);GO:0001556(oocyte maturation);GO:0007568(aging);GO:0030330(DNA damage response, signal transduction by p53 class mediator);GO:0031667(response to nutrient levels);GO:0042493(response to drug);GO:0042593(glucose homeostasis);GO:0045665(negative regulation of neuron differentiation);GO:0048854(brain morphogenesis);GO:0071333(cellular response to glucose stimulus);GO:0071386(cellular response to corticosterone stimulus);GO:0071456(cellular response to hypoxia);GO:0071548(response to dexamethasone);GO:0090090(negative regulation of canonical Wnt signaling pathway);GO:0097150(neuronal stem cell population maintenance);GO:0097192(extrinsic apoptotic signaling pathway in absence of ligand);GO:1901300(positive regulation of hydrogen peroxide-mediated programmed cell death);GO:1903428(positive regulation of reactive oxygen species biosynthetic process);GO:1904646(cellular response to amyloid-beta);GO:1990090(cellular response to nerve growth factor stimulus);GO:1990785(response to water-immersion restraint stress);GO:2000177(regulation of neural precursor cell proliferation);GO:2000353(positive regulation of endothelial cell apoptotic process);GO:2000377(regulation of reactive oxygen species metabolic process);GO:0005739(mitochondrion);GO:0016020(membrane)","04068(FoxO signaling pathway);04151(PI3K-Akt signaling pathway);04152(AMPK signaling pathway);04137(Mitophagy - animal);04218(Cellular senescence);04062(Chemokine signaling pathway);04917(Prolactin signaling pathway);04722(Neurotrophin signaling pathway);04211(Longevity regulating pathway - mammal);04213(Longevity regulating pathway - multiple species);05213(Endometrial cancer);05223(Non-small cell lung cancer);01521(EGFR tyrosine kinase inhibitor resistance)","K09408","NA","forkhead box O3 [Source:HGNC Symbol;Acc:HGNC:3821]",{"v":10.651316,"d":"10.65"},{"v":0.302224,"d":"0.30"},{"v":35.243117687543,"d":"35.24"},{"v":5.1392696489245,"d":"5.14"},{"v":1.90447509297844e-10,"d":"0.00"},{"v":1.01853386864479E-7,"d":"0.00"},"up","yes"]
[194125,"j","chr9","-",129807881,129824134,"MSTRG.15033.1",6,2499,"MSTRG.15033","TOR1A","NA","NA","NA","NA","NA",{"v":0.499042,"d":"0.50"},{"v":13.359907,"d":"13.36"},{"v":0.0373537031358078,"d":"0.04"},{"v":-4.74260491514476,"d":"-4.74"},{"v":2.30666687046534E-10,"d":"0.00"},{"v":1.20116642191495E-7,"d":"0.00"},"down","yes"]
[11394,"j","chr1","+",154325553,154350945,"MSTRG.1011.1",28,5587,"MSTRG.1011","ATP8B2","NA","NA","NA","NA","NA",{"v":14.239856,"d":"14.24"},{"v":0.4167,"d":"0.42"},{"v":34.1729205663547,"d":"34.17"},{"v":5.09478164691383,"d":"5.09"},{"v":2.49700375496298e-10,"d":"0.00"},{"v":1.25180607950029E-7,"d":"0.00"},"up","yes"]
[31077,0,"chr11","-",65120630,65122057,"ENST00000531743",4,697,"MSTRG.2528","FAU","GO:0003723(RNA binding);GO:0006412(translation);GO:0030529(intracellular ribonucleoprotein complex);GO:0005622(intracellular);GO:0003735(structural constituent of ribosome);GO:0005840(ribosome);GO:0022627(cytosolic small ribosomal subunit);GO:0005615(extracellular space);GO:0008150(biological_process);GO:0005575(cellular_component);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0002227(innate immune response in mucosa);GO:0019731(antibacterial humoral response);GO:0050830(defense response to Gram-positive bacterium);GO:0061844(antimicrobial humoral immune response mediated by antimicrobial peptide);GO:0006413(translational initiation);GO:0006364(rRNA processing);GO:0000184(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay);GO:0019083(viral transcription);GO:0006614(SRP-dependent cotranslational protein targeting to membrane);GO:0015935(small ribosomal subunit)","03010(Ribosome)","NA","NA","FAU, ubiquitin like and ribosomal protein S30 fusion [Source:HGNC Symbol;Acc:HGNC:3597]",{"v":2.491885,"d":"2.49"},{"v":65.351982,"d":"65.35"},{"v":0.038130213097439,"d":"0.04"},{"v":-4.7129215959318,"d":"-4.71"},{"v":2.53043476753646e-10,"d":"0.00"},{"v":1.25180607950029E-7,"d":"0.00"},"down","yes"]
[67257,"j","chr16","-",79789,138361,"MSTRG.5474.1",17,2517,"MSTRG.5474","NPRL3","NA","NA","NA","NA","NA",{"v":27.126963,"d":"27.13"},{"v":0.836928,"d":"0.84"},{"v":32.4125408637302,"d":"32.41"},{"v":5.01848021482791,"d":"5.02"},{"v":4.09046672279133e-10,"d":"0.00"},{"v":1.95586274861009e-07,"d":"0.00"},"up","yes"]
[134704,0,"chr3","+",37243252,37366745,"ENST00000356847",23,7673,"MSTRG.10802","GOLGA4","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005794(Golgi apparatus);GO:0043231(intracellular membrane-bounded organelle);GO:0005829(cytosol);GO:0005515(protein binding);GO:0000139(Golgi membrane);GO:0000042(protein targeting to Golgi);GO:0045773(positive regulation of axon extension);GO:0070062(extracellular exosome);GO:0016192(vesicle-mediated transport);GO:0005802(trans-Golgi network);GO:0051020(GTPase binding);GO:0043001(Golgi to plasma membrane protein transport)","NA","NA","NA","golgin A4 [Source:HGNC Symbol;Acc:HGNC:4427]",{"v":5.681129,"d":"5.68"},{"v":0.172445,"d":"0.17"},{"v":32.9445852300734,"d":"32.94"},{"v":5.04196945834029,"d":"5.04"},{"v":4.15131571869939e-10,"d":"0.00"},{"v":1.95586274861009e-07,"d":"0.00"},"up","yes"]
[183170,"j","chr8","+",38805480,38853121,"MSTRG.14302.23",12,7317,"MSTRG.14302","TACC1","NA","NA","NA","NA","NA",{"v":9.210458,"d":"9.21"},{"v":0.29332,"d":"0.29"},{"v":31.4007159416337,"d":"31.40"},{"v":4.97272554807017,"d":"4.97"},{"v":5.67234873599038e-10,"d":"0.00"},{"v":2.61033573925064E-7,"d":"0.00"},"up","yes"]
[62006,0,"chr15","+",44711959,44716559,"ENST00000560681",3,572,"MSTRG.5036","B2M","GO:0016020(membrane);GO:0005794(Golgi apparatus);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0006955(immune response);GO:0005615(extracellular space);GO:0002376(immune system process);GO:0005925(focal adhesion);GO:0050776(regulation of immune response);GO:0042802(identical protein binding);GO:0002474(antigen processing and presentation of peptide antigen via MHC class I);GO:0042612(MHC class I protein complex);GO:0070062(extracellular exosome);GO:0044267(cellular protein metabolic process);GO:0001895(retina homeostasis);GO:0002479(antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent);GO:0045087(innate immune response);GO:0043312(neutrophil degranulation);GO:0030670(phagocytic vesicle membrane);GO:0009986(cell surface);GO:1990712(HFE-transferrin receptor complex);GO:0005788(endoplasmic reticulum lumen);GO:0035580(specific granule lumen);GO:1904724(tertiary granule lumen);GO:0000139(Golgi membrane);GO:0048260(positive regulation of receptor-mediated endocytosis);GO:0060333(interferon-gamma-mediated signaling pathway);GO:0012507(ER to Golgi transport vesicle membrane);GO:0032092(positive regulation of protein binding);GO:0050690(regulation of defense response to virus by virus);GO:0031901(early endosome membrane);GO:0002480(antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent);GO:0055038(recycling endosome membrane);GO:0002726(positive regulation of T cell cytokine production);GO:0019885(antigen processing and presentation of endogenous peptide antigen via MHC class I);GO:0055072(iron ion homeostasis);GO:0071281(cellular response to iron ion);GO:0001916(positive regulation of T cell mediated cytotoxicity);GO:0002237(response to molecule of bacterial origin);GO:0002481(antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent);GO:0006826(iron ion transport);GO:0010977(negative regulation of neuron projection development);GO:0033077(T cell differentiation in thymus);GO:0033216(ferric iron import);GO:0042026(protein refolding);GO:0042493(response to drug);GO:0045646(regulation of erythrocyte differentiation);GO:0046686(response to cadmium ion);GO:0071283(cellular response to iron(III) ion);GO:1900121(negative regulation of receptor binding);GO:1900122(positive regulation of receptor binding);GO:1904434(positive regulation of ferrous iron binding);GO:1904437(positive regulation of transferrin receptor binding);GO:1904440(positive regulation of ferrous iron import across plasma membrane);GO:0009897(external side of plasma membrane);GO:0031905(early endosome lumen)","04612(Antigen processing and presentation)","NA","NA","beta-2-microglobulin [Source:HGNC Symbol;Acc:HGNC:914]",{"v":2.437607,"d":"2.44"},{"v":57.824165,"d":"57.82"},{"v":0.042155507130972,"d":"0.04"},{"v":-4.56813507482204,"d":"-4.57"},{"v":7.01950416481219e-10,"d":"0.00"},{"v":3.15686246393872e-07,"d":"0.00"},"down","yes"]
[138481,0,"chr3","-",98515473,98523043,"ENST00000341181",5,2161,"MSTRG.11081","CLDND1","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0009986(cell surface);GO:0016324(apical plasma membrane)","NA","NA","NA","claudin domain containing 1 [Source:HGNC Symbol;Acc:HGNC:1322]",{"v":0.852679,"d":"0.85"},{"v":19.760067,"d":"19.76"},{"v":0.0431516249413527,"d":"0.04"},{"v":-4.53444130242863,"d":"-4.53"},{"v":7.52752359942441e-10,"d":"0.00"},{"v":3.31010304412023e-07,"d":"0.00"},"down","yes"]
[94332,0,"chr19","+",1438419,1440494,"ENST00000593052",4,629,"MSTRG.7611","RPS15","GO:0003723(RNA binding);GO:0030529(intracellular ribonucleoprotein complex);GO:0003735(structural constituent of ribosome);GO:0006412(translation);GO:0005840(ribosome);GO:0015935(small ribosomal subunit);GO:0005634(nucleus);GO:0016020(membrane);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0022627(cytosolic small ribosomal subunit);GO:0005654(nucleoplasm);GO:0005925(focal adhesion);GO:0006364(rRNA processing);GO:0042274(ribosomal small subunit biogenesis);GO:0000028(ribosomal small subunit assembly);GO:0005829(cytosol);GO:0006413(translational initiation);GO:0000184(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay);GO:0019083(viral transcription);GO:0001649(osteoblast differentiation);GO:0006614(SRP-dependent cotranslational protein targeting to membrane);GO:0000056(ribosomal small subunit export from nucleus)","03010(Ribosome)","K02958","NA","ribosomal protein S15 [Source:HGNC Symbol;Acc:HGNC:10388]",{"v":7.381047,"d":"7.38"},{"v":166.631973,"d":"166.63"},{"v":0.0442955026404206,"d":"0.04"},{"v":-4.49669596159789,"d":"-4.50"},{"v":7.71123316462501e-10,"d":"0.00"},{"v":3.31717134481738e-07,"d":"0.00"},"down","yes"]
[10758,0,"chr1","+",151156629,151159749,"ENST00000368910",2,1178,"MSTRG.944","TNFAIP8L2","GO:0005515(protein binding);GO:0002376(immune system process);GO:0045087(innate immune response);GO:0005737(cytoplasm);GO:0050728(negative regulation of inflammatory response);GO:0050868(negative regulation of T cell activation)","NA","NA","NA","TNF alpha induced protein 8 like 2 [Source:HGNC Symbol;Acc:HGNC:26277]",{"v":20.966684,"d":"20.97"},{"v":0.661353,"d":"0.66"},{"v":31.7027124697401,"d":"31.70"},{"v":4.98653437686811,"d":"4.99"},{"v":8.18260875286034e-10,"d":"0.00"},{"v":3.44505238301277e-07,"d":"0.00"},"up","yes"]
[23198,"j","chr10","-",103088038,103187247,"MSTRG.1950.6",21,3802,"MSTRG.1950","NT5C2","NA","NA","NA","NA","NA",{"v":8.478184,"d":"8.48"},{"v":0.277216,"d":"0.28"},{"v":30.5833140944246,"d":"30.58"},{"v":4.93467284457262,"d":"4.93"},{"v":9.57372347931513e-10,"d":"0.00"},{"v":3.94676750434766e-07,"d":"0.00"},"up","yes"]
[198086,0,"chrX","+",71118723,71142447,"ENST00000374080",45,6795,"ENSG00000184634","MED12","GO:0005634(nucleus);GO:0016020(membrane);GO:0008013(beta-catenin binding);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0001104(RNA polymerase II transcription cofactor activity);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0016592(mediator complex);GO:0005515(protein binding);GO:0030374(ligand-dependent nuclear receptor transcription coactivator activity);GO:0045893(positive regulation of transcription, DNA-templated);GO:0006367(transcription initiation from RNA polymerase II promoter);GO:0005654(nucleoplasm);GO:0004872(receptor activity);GO:0030178(negative regulation of Wnt signaling pathway);GO:0008022(protein C-terminus binding);GO:0003713(transcription coactivator activity);GO:0019904(protein domain specific binding);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0003712(transcription cofactor activity);GO:0030518(intracellular steroid hormone receptor signaling pathway);GO:0030521(androgen receptor signaling pathway);GO:0042809(vitamin D receptor binding);GO:0046966(thyroid hormone receptor binding);GO:0001105(RNA polymerase II transcription coactivator activity);GO:0000980(RNA polymerase II distal enhancer sequence-specific DNA binding);GO:0001190(transcriptional activator activity, RNA polymerase II transcription factor binding);GO:0003682(chromatin binding);GO:0008134(transcription factor binding);GO:0061630(ubiquitin protein ligase activity);GO:0001756(somitogenesis);GO:0001843(neural tube closure);GO:0007492(endoderm development);GO:0007507(heart development);GO:0014003(oligodendrocyte development);GO:0014044(Schwann cell development);GO:0016567(protein ubiquitination);GO:0019827(stem cell population maintenance);GO:0021510(spinal cord development);GO:0021915(neural tube development);GO:0036342(post-anal tail morphogenesis);GO:0048568(embryonic organ development);GO:0048702(embryonic neurocranium morphogenesis);GO:0060070(canonical Wnt signaling pathway);GO:0060071(Wnt signaling pathway, planar cell polarity pathway);GO:0090245(axis elongation involved in somitogenesis);GO:1990403(embryonic brain development);GO:0000151(ubiquitin ligase complex)","04919(Thyroid hormone signaling pathway)","K15162","NA","mediator complex subunit 12 [Source:HGNC Symbol;Acc:HGNC:11957]",{"v":4.619474,"d":"4.62"},{"v":0.151828,"d":"0.15"},{"v":30.4257054034829,"d":"30.43"},{"v":4.9272188063164,"d":"4.93"},{"v":1.00138158663235E-9,"d":"0.00"},{"v":4.04394670128183e-07,"d":"0.00"},"up","yes"]
[45054,"j","chr12","-",89588051,89709348,"MSTRG.3587.2",21,6947,"MSTRG.3587","ATP2B1","NA","NA","NA","NA","NA",{"v":9.18294,"d":"9.18"},{"v":0.322619,"d":"0.32"},{"v":28.4637296625431,"d":"28.46"},{"v":4.83105280851259,"d":"4.83"},{"v":1.4025676771491e-09,"d":"0.00"},{"v":5.48837360416965e-07,"d":"0.00"},"up","yes"]
[75414,0,"chr16","+",71845991,71857333,"ENST00000427980",3,7886,"MSTRG.6105","ATXN1L","GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005730(nucleolus);GO:0005654(nucleoplasm);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0042995(cell projection);GO:0005515(protein binding);GO:0030425(dendrite);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0030198(extracellular matrix organization);GO:0048286(lung alveolus development);GO:1902035(positive regulation of hematopoietic stem cell proliferation)","NA","NA","NA","ataxin 1 like [Source:HGNC Symbol;Acc:HGNC:33279]",{"v":7.871546,"d":"7.87"},{"v":0.277066,"d":"0.28"},{"v":28.4103643175272,"d":"28.41"},{"v":4.82834542679214,"d":"4.83"},{"v":1.41452927942517E-9,"d":"0.00"},{"v":5.48837360416965e-07,"d":"0.00"},"up","yes"]
[3490,"j","chr1","+",28914579,29117966,"MSTRG.337.13",18,3742,"MSTRG.337","EPB41","NA","NA","NA","NA","NA",{"v":7.839264,"d":"7.84"},{"v":0.268037,"d":"0.27"},{"v":29.24694724982,"d":"29.25"},{"v":4.87021414121114,"d":"4.87"},{"v":1.52996188771868E-9,"d":"0.00"},{"v":5.82209342964948E-7,"d":"0.00"},"up","yes"]
[31200,"o","chr11","+",65416571,65445540,"MSTRG.2544.1",2,23741,"MSTRG.2544","NEAT1","NA","NA","NA","NA","NA",{"v":4.237058,"d":"4.24"},{"v":0.153352,"d":"0.15"},{"v":27.6296233502008,"d":"27.63"},{"v":4.78814399020819,"d":"4.79"},{"v":1.63681562202764E-9,"d":"0.00"},{"v":6.11119009975148e-07,"d":"0.00"},"up","yes"]
[185934,0,"chr8","+",99013266,99877580,"ENST00000357162",62,14019,"MSTRG.14483","VPS13B","GO:0006810(transport);GO:0015031(protein transport)","NA","NA","NA","vacuolar protein sorting 13 homolog B [Source:HGNC Symbol;Acc:HGNC:2183]",{"v":4.084013,"d":"4.08"},{"v":0.147772,"d":"0.15"},{"v":27.6372587499662,"d":"27.64"},{"v":4.78854262146902,"d":"4.79"},{"v":1.79715291879211e-09,"d":"0.00"},{"v":6.56955829849941e-07,"d":"0.00"},"up","yes"]
[30851,"j","chr11","-",64764390,64778534,"MSTRG.2520.1",12,3414,"MSTRG.2520","SF1","NA","NA","NA","NA","NA",{"v":25.814487,"d":"25.81"},{"v":0.943422,"d":"0.94"},{"v":27.362608673531,"d":"27.36"},{"v":4.77413387412284,"d":"4.77"},{"v":1.82598396208544E-9,"d":"0.00"},{"v":6.56955829849941e-07,"d":"0.00"},"up","yes"]
[89230,0,"chr17","-",81117295,81166017,"ENST00000326724",14,5257,"ENSG00000181409","AATK","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0048471(perinuclear region of cytoplasm)","NA","NA","NA","apoptosis associated tyrosine kinase [Source:HGNC Symbol;Acc:HGNC:21]",{"v":8.35521,"d":"8.36"},{"v":0.303345,"d":"0.30"},{"v":27.5435889828413,"d":"27.54"},{"v":4.78364465255898,"d":"4.78"},{"v":2.09732490378271E-9,"d":"0.00"},{"v":7.41104735643791E-7,"d":"0.00"},"up","yes"]
[9225,0,"chr1","-",111722064,111739424,"ENST00000357260",2,5980,"MSTRG.801","FAM212B","GO:0005634(nucleus);GO:0071901(negative regulation of protein serine/threonine kinase activity);GO:0019901(protein kinase binding);GO:0030291(protein serine/threonine kinase inhibitor activity)","NA","NA","NA","family with sequence similarity 212 member B [Source:HGNC Symbol;Acc:HGNC:28045]",{"v":0.725663,"d":"0.73"},{"v":14.685409,"d":"14.69"},{"v":0.0494138774071597,"d":"0.05"},{"v":-4.3389399241815,"d":"-4.34"},{"v":2.14095506072012e-09,"d":"0.00"},{"v":7.43249451605785E-7,"d":"0.00"},"down","yes"]
[162624,"j","chr6","-",6144072,6321686,"MSTRG.12650.2",16,3957,"MSTRG.12650","F13A1","NA","NA","NA","NA","NA",{"v":8.162477,"d":"8.16"},{"v":0.296372,"d":"0.30"},{"v":27.5413230669564,"d":"27.54"},{"v":4.7835259621412,"d":"4.78"},{"v":2.41836730356421e-09,"d":"0.00"},{"v":8.14066510339017e-07,"d":"0.00"},"up","yes"]
[31992,0,"chr11","-",67438076,67443512,"ENST00000341356",11,1881,"MSTRG.2613","CORO1B","GO:0005737(cytoplasm);GO:0003779(actin binding);GO:0005829(cytosol);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0048471(perinuclear region of cytoplasm);GO:0005925(focal adhesion);GO:0045296(cadherin binding);GO:0051015(actin filament binding);GO:0030027(lamellipodium);GO:0031252(cell leading edge);GO:0070062(extracellular exosome);GO:0071944(cell periphery);GO:0001725(stress fiber);GO:0042802(identical protein binding);GO:0051017(actin filament bundle assembly);GO:0016477(cell migration);GO:0005884(actin filament);GO:0042060(wound healing);GO:0035767(endothelial cell chemotaxis);GO:0005886(plasma membrane);GO:0031529(ruffle organization);GO:2000394(positive regulation of lamellipodium morphogenesis);GO:0071672(negative regulation of smooth muscle cell chemotaxis);GO:0034315(regulation of Arp2/3 complex-mediated actin nucleation);GO:0036120(cellular response to platelet-derived growth factor stimulus);GO:0071933(Arp2/3 complex binding);GO:0030036(actin cytoskeleton organization);GO:0034316(negative regulation of Arp2/3 complex-mediated actin nucleation);GO:0090135(actin filament branching);GO:1902463(protein localization to cell leading edge)","NA","NA","NA","coronin 1B [Source:HGNC Symbol;Acc:HGNC:2253]",{"v":0.473644,"d":"0.47"},{"v":10.161463,"d":"10.16"},{"v":0.0466117920224676,"d":"0.05"},{"v":-4.42316121042653,"d":"-4.42"},{"v":2.42722478825561e-09,"d":"0.00"},{"v":8.14066510339017e-07,"d":"0.00"},"down","yes"]
[66136,"j","chr15","+",88635627,88656415,"MSTRG.5390.2",7,1939,"MSTRG.5390","ISG20","NA","NA","NA","NA","NA",{"v":0.947529,"d":"0.95"},{"v":19.00452,"d":"19.00"},{"v":0.0498580863920794,"d":"0.05"},{"v":-4.32602867809728,"d":"-4.33"},{"v":2.94700454399784e-09,"d":"0.00"},{"v":9.71922098610489e-07,"d":"0.00"},"down","yes"]
[3758,"j","chr1","-",31906421,31938352,"MSTRG.357.2",8,3749,"MSTRG.357","PTP4A2","NA","NA","NA","NA","NA",{"v":16.215212,"d":"16.22"},{"v":0.623567,"d":"0.62"},{"v":26.0039610819687,"d":"26.00"},{"v":4.70065949498905,"d":"4.70"},{"v":3.04599532400813E-9,"d":"0.00"},{"v":9.88100909368407e-07,"d":"0.00"},"up","yes"]
[4524,0,"chr1","+",39204246,39487177,"ENST00000564288",101,24828,"MSTRG.449","MACF1","GO:0003779(actin binding);GO:0005509(calcium ion binding);GO:0005856(cytoskeleton);GO:0008017(microtubule binding);GO:0016055(Wnt signaling pathway);GO:0016887(ATPase activity);GO:0003723(RNA binding);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0046872(metal ion binding);GO:0005794(Golgi apparatus);GO:0005886(plasma membrane);GO:0042995(cell projection);GO:0005515(protein binding);GO:0005874(microtubule);GO:0045296(cadherin binding);GO:0051015(actin filament binding);GO:0045773(positive regulation of axon extension);GO:0032587(ruffle membrane);GO:0042060(wound healing);GO:0051893(regulation of focal adhesion assembly);GO:0032886(regulation of microtubule-based process);GO:0030177(positive regulation of Wnt signaling pathway);GO:0010632(regulation of epithelial cell migration);GO:0043001(Golgi to plasma membrane protein transport);GO:0016021(integral component of membrane);GO:0030054(cell junction);GO:0015629(actin cytoskeleton)","NA","NA","NA","microtubule-actin crosslinking factor 1 [Source:HGNC Symbol;Acc:HGNC:13664]",{"v":0.073859,"d":"0.07"},{"v":1.461481,"d":"1.46"},{"v":0.0505370921688342,"d":"0.05"},{"v":-4.30651353368932,"d":"-4.31"},{"v":3.39800227560209e-09,"d":"0.00"},{"v":1.08451079080023e-06,"d":"0.00"},"down","yes"]
[161043,0,"chr5","+",171387829,171410884,"ENST00000351986",10,1237,"MSTRG.12532","NPM1","GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0006334(nucleosome assembly);GO:0042803(protein homodimerization activity);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0007165(signal transduction);GO:0006281(DNA repair);GO:0004860(protein kinase inhibitor activity);GO:0003713(transcription coactivator activity);GO:0045893(positive regulation of transcription, DNA-templated);GO:0005654(nucleoplasm);GO:0006886(intracellular protein transport);GO:0045727(positive regulation of translation);GO:0005730(nucleolus);GO:0005925(focal adhesion);GO:0005813(centrosome);GO:0005815(microtubule organizing center);GO:0019843(rRNA binding);GO:0047485(protein N-terminus binding);GO:0000055(ribosomal large subunit export from nucleus);GO:0000056(ribosomal small subunit export from nucleus);GO:0006407(rRNA export from nucleus);GO:0006884(cell volume homeostasis);GO:0006913(nucleocytoplasmic transport);GO:0008104(protein localization);GO:0008284(positive regulation of cell proliferation);GO:0010608(posttranscriptional regulation of gene expression);GO:0010629(negative regulation of gene expression);GO:0010824(regulation of centrosome duplication);GO:0010825(positive regulation of centrosome duplication);GO:0016049(cell growth);GO:0031328(positive regulation of cellular biosynthetic process);GO:0031398(positive regulation of protein ubiquitination);GO:0031647(regulation of protein stability);GO:0042273(ribosomal large subunit biogenesis);GO:0042274(ribosomal small subunit biogenesis);GO:0043066(negative regulation of apoptotic process);GO:0043516(regulation of DNA damage response, signal transduction by p53 class mediator);GO:0045860(positive regulation of protein kinase activity);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0048025(negative regulation of mRNA splicing, via spliceosome);GO:0050821(protein stabilization);GO:0051260(protein homooligomerization);GO:0051726(regulation of cell cycle);GO:1904751(positive regulation of protein localization to nucleolus);GO:0001652(granular component);GO:0005829(cytosol);GO:0015934(large ribosomal subunit);GO:0015935(small ribosomal subunit);GO:0016607(nuclear speck);GO:0006977(DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest);GO:0019901(protein kinase binding);GO:0008285(negative regulation of cell proliferation);GO:0016032(viral process);GO:0034080(CENP-A containing nucleosome assembly);GO:0007098(centrosome cycle);GO:0051092(positive regulation of NF-kappaB transcription factor activity);GO:0008134(transcription factor binding);GO:0042393(histone binding);GO:0046982(protein heterodimerization activity);GO:0043234(protein complex);GO:0030957(Tat protein binding);GO:0051082(unfolded protein binding);GO:0030529(intracellular ribonucleoprotein complex);GO:0007569(cell aging);GO:0006950(response to stress);GO:0051059(NF-kappaB binding);GO:0032993(protein-DNA complex);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0033613(activating transcription factor binding);GO:0001047(core promoter binding);GO:0034644(cellular response to UV);GO:0001105(RNA polymerase II transcription coactivator activity);GO:0043023(ribosomal large subunit binding);GO:0043024(ribosomal small subunit binding);GO:0010826(negative regulation of centrosome duplication);GO:0032071(regulation of endodeoxyribonuclease activity);GO:0042255(ribosome assembly);GO:0044387(negative regulation of protein kinase activity by regulation of protein phosphorylation);GO:0046599(regulation of centriole replication);GO:0051259(protein oligomerization);GO:0060699(regulation of endoribonuclease activity);GO:0060735(regulation of eIF2 alpha phosphorylation by dsRNA);GO:1902751(positive regulation of cell cycle G2/M phase transition);GO:0031616(spindle pole centrosome)","NA","NA","NA","nucleophosmin [Source:HGNC Symbol;Acc:HGNC:7910]",{"v":0.921261,"d":"0.92"},{"v":18.505671,"d":"18.51"},{"v":0.0497826314971232,"d":"0.05"},{"v":-4.32821369695059,"d":"-4.33"},{"v":3.76507012566229e-09,"d":"0.00"},{"v":1.18259059756517E-6,"d":"0.00"},"down","yes"]
[78164,0,"chr17","-",4945667,4947469,"ENST00000574872",2,1173,"MSTRG.6340","PFN1","GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0003779(actin binding);GO:0030036(actin cytoskeleton organization);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0005925(focal adhesion);GO:0005829(cytosol);GO:0045296(cadherin binding);GO:0070062(extracellular exosome);GO:0050821(protein stabilization);GO:0005938(cell cortex);GO:0072562(blood microparticle);GO:0060071(Wnt signaling pathway, planar cell polarity pathway);GO:0005546(phosphatidylinositol-4,5-bisphosphate binding);GO:0070064(proline-rich region binding);GO:0030838(positive regulation of actin filament polymerization);GO:0010634(positive regulation of epithelial cell migration);GO:0032781(positive regulation of ATPase activity);GO:0003785(actin monomer binding);GO:0051497(negative regulation of stress fiber assembly);GO:0030837(negative regulation of actin filament polymerization);GO:0000774(adenyl-nucleotide exchange factor activity);GO:0005102(receptor binding);GO:0017048(Rho GTPase binding);GO:0001843(neural tube closure);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0010033(response to organic substance);GO:0032232(negative regulation of actin filament bundle assembly);GO:0032233(positive regulation of actin filament bundle assembly);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0050434(positive regulation of viral transcription);GO:0051054(positive regulation of DNA metabolic process);GO:0051496(positive regulation of stress fiber assembly);GO:0071363(cellular response to growth factor stimulus);GO:1900029(positive regulation of ruffle assembly);GO:0005615(extracellular space);GO:0043005(neuron projection);GO:0045202(synapse)","04015(Rap1 signaling pathway);04810(Regulation of actin cytoskeleton);05132(Salmonella infection);05131(Shigellosis)","NA","NA","profilin 1 [Source:HGNC Symbol;Acc:HGNC:8881]",{"v":10.098692,"d":"10.10"},{"v":189.069458,"d":"189.07"},{"v":0.0534126035311319,"d":"0.05"},{"v":-4.22667598144979,"d":"-4.23"},{"v":4.04440025558291e-09,"d":"0.00"},{"v":1.25047800402304e-06,"d":"0.00"},"down","yes"]
[105421,0,"chr19","+",54200874,54207647,"ENST00000391751",4,510,"MSTRG.8410","RPS9","GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0006412(translation);GO:0030529(intracellular ribonucleoprotein complex);GO:0005622(intracellular);GO:0003735(structural constituent of ribosome);GO:0005840(ribosome);GO:0015935(small ribosomal subunit);GO:0005515(protein binding);GO:0022627(cytosolic small ribosomal subunit);GO:0019843(rRNA binding);GO:0005730(nucleolus);GO:0005925(focal adhesion);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0008284(positive regulation of cell proliferation);GO:0006413(translational initiation);GO:0006364(rRNA processing);GO:0000184(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay);GO:0019083(viral transcription);GO:0006614(SRP-dependent cotranslational protein targeting to membrane);GO:0045182(translation regulator activity);GO:0045903(positive regulation of translational fidelity)","03010(Ribosome)","K02997","NA","ribosomal protein S9 [Source:HGNC Symbol;Acc:HGNC:10442]",{"v":3.161153,"d":"3.16"},{"v":61.096085,"d":"61.10"},{"v":0.051740680274358,"d":"0.05"},{"v":-4.27255716741054,"d":"-4.27"},{"v":4.43767712175946e-09,"d":"0.00"},{"v":1.34957806377954E-6,"d":"0.00"},"down","yes"]
[71995,0,"chr16","+",30658431,30670814,"ENST00000356166",18,5200,"MSTRG.5856","FBRS","NA","NA","NA","NA","fibrosin [Source:HGNC Symbol;Acc:HGNC:20442]",{"v":10.697307,"d":"10.70"},{"v":0.426751,"d":"0.43"},{"v":25.066858659968,"d":"25.07"},{"v":4.64770930607136,"d":"4.65"},{"v":4.50132161964067E-9,"d":"0.00"},{"v":1.34957806377954E-6,"d":"0.00"},"up","yes"]
[160065,"j","chr5","+",150486310,150554279,"MSTRG.12459.4",16,4203,"MSTRG.12459","NDST1","NA","NA","NA","NA","NA",{"v":6.253127,"d":"6.25"},{"v":0.255457,"d":"0.26"},{"v":24.4781978963191,"d":"24.48"},{"v":4.61342544451335,"d":"4.61"},{"v":6.90843019615424E-9,"d":"0.00"},{"v":2.04035845852985e-06,"d":"0.00"},"up","yes"]
[38831,0,"chr12","-",10372353,10390018,"ENST00000240618",8,1553,"MSTRG.3171","KLRK1","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0030246(carbohydrate binding);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0030154(cell differentiation);GO:0002376(immune system process);GO:0045087(innate immune response);GO:0032394(MHC class Ib receptor activity);GO:0042288(MHC class I protein binding);GO:0042803(protein homodimerization activity);GO:0002223(stimulatory C-type lectin receptor signaling pathway);GO:0030101(natural killer cell activation);GO:0032729(positive regulation of interferon-gamma production);GO:0045429(positive regulation of nitric oxide biosynthetic process);GO:0045954(positive regulation of natural killer cell mediated cytotoxicity);GO:0050830(defense response to Gram-positive bacterium);GO:0071222(cellular response to lipopolysaccharide);GO:0009897(external side of plasma membrane);GO:0009986(cell surface);GO:0002250(adaptive immune response);GO:0050776(regulation of immune response);GO:0004872(receptor activity);GO:0005887(integral component of plasma membrane);GO:0007165(signal transduction);GO:0031295(T cell costimulation);GO:0034260(negative regulation of GTPase activity);GO:0042267(natural killer cell mediated cytotoxicity);GO:2000502(negative regulation of natural killer cell chemotaxis)","04650(Natural killer cell mediated cytotoxicity);05144(Malaria)","K06728","NA","killer cell lectin like receptor K1 [Source:HGNC Symbol;Acc:HGNC:18788]",{"v":15.289059,"d":"15.29"},{"v":0.632493,"d":"0.63"},{"v":24.1726928203158,"d":"24.17"},{"v":4.59530629211659,"d":"4.60"},{"v":8.6457165346196e-09,"d":"0.00"},{"v":2.50247573537444e-06,"d":"0.00"},"up","yes"]
[81817,0,"chr17","-",31303766,31314112,"ENST00000330927",2,1999,"MSTRG.6660","EVI2B","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005887(integral component of plasma membrane)","NA","NA","NA","ecotropic viral integration site 2B [Source:HGNC Symbol;Acc:HGNC:3500]",{"v":127.695251,"d":"127.70"},{"v":5.638536,"d":"5.64"},{"v":22.6468805023148,"d":"22.65"},{"v":4.50124043461644,"d":"4.50"},{"v":8.72603728223348e-09,"d":"0.00"},{"v":2.50247573537444e-06,"d":"0.00"},"up","yes"]
[14915,0,"chr1","+",202348699,202592706,"ENST00000608999",24,15248,"MSTRG.1305","PPP1R12B","GO:0019901(protein kinase binding);GO:0005737(cytoplasm);GO:0043085(positive regulation of catalytic activity);GO:0005515(protein binding);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0000086(G2/M transition of mitotic cell cycle);GO:0007165(signal transduction);GO:0030018(Z disc);GO:0031672(A band);GO:0008047(enzyme activator activity);GO:0006937(regulation of muscle contraction)","04510(Focal adhesion);04810(Regulation of actin cytoskeleton);04921(Oxytocin signaling pathway);04270(Vascular smooth muscle contraction);05205(Proteoglycans in cancer)","K12329","NA","protein phosphatase 1 regulatory subunit 12B [Source:HGNC Symbol;Acc:HGNC:7619]",{"v":3.10686,"d":"3.11"},{"v":0.135025,"d":"0.14"},{"v":23.0095167561563,"d":"23.01"},{"v":4.52415877941339,"d":"4.52"},{"v":9.69957576852474E-9,"d":"0.00"},{"v":2.74193150439382e-06,"d":"0.00"},"up","yes"]
[182241,0,"chr8","+",23541470,23572203,"ENST00000523883",4,3651,"MSTRG.14243","SLC25A37","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005743(mitochondrial inner membrane);GO:0005739(mitochondrion);GO:0006811(ion transport);GO:0006839(mitochondrial transport);GO:0055072(iron ion homeostasis);GO:0034755(iron ion transmembrane transport);GO:0005381(iron ion transmembrane transporter activity);GO:0048250(mitochondrial iron ion transport)","NA","NA","NA","solute carrier family 25 member 37 [Source:HGNC Symbol;Acc:HGNC:29786]",{"v":0.248626,"d":"0.25"},{"v":4.555346,"d":"4.56"},{"v":0.0545789496560744,"d":"0.05"},{"v":-4.1955115588225,"d":"-4.20"},{"v":9.91668393461855e-09,"d":"0.00"},{"v":2.7638217140596e-06,"d":"0.00"},"down","yes"]
[86953,0,"chr17","-",64319415,64390878,"ENST00000563924",16,6831,"MSTRG.7102","PECAM1","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0001525(angiogenesis);GO:0001886(endothelial cell morphogenesis);GO:0007266(Rho protein signal transduction);GO:0030334(regulation of cell migration);GO:0042060(wound healing);GO:0042531(positive regulation of tyrosine phosphorylation of STAT protein);GO:0043542(endothelial cell migration);GO:0090673(endothelial cell-matrix adhesion);GO:0005886(plasma membrane);GO:0009897(external side of plasma membrane);GO:0030485(smooth muscle contractile fiber);GO:0045121(membrane raft);GO:0071944(cell periphery)","04514(Cell adhesion molecules (CAMs));04670(Leukocyte transendothelial migration);05418(Fluid shear stress and atherosclerosis);05144(Malaria)","K06471","NA","platelet and endothelial cell adhesion molecule 1 [Source:HGNC Symbol;Acc:HGNC:8823]",{"v":0.640016,"d":"0.64"},{"v":10.90834,"d":"10.91"},{"v":0.0586721719345015,"d":"0.06"},{"v":-4.09117979089419,"d":"-4.09"},{"v":1.05171531400499E-8,"d":"0.00"},{"v":2.89046425465705e-06,"d":"0.00"},"down","yes"]
[164342,"o","chr6","+",31268940,31354573,"MSTRG.12848.1",3,329,"MSTRG.12848","USP8P1","NA","NA","NA","NA","NA",{"v":2.419763,"d":"2.42"},{"v":44.296997,"d":"44.30"},{"v":0.0546258925859015,"d":"0.05"},{"v":-4.19427124136318,"d":"-4.19"},{"v":1.09905322248539e-08,"d":"0.00"},{"v":2.97918700911518E-6,"d":"0.00"},"down","yes"]
[164694,0,"chr6","+",31815543,31817946,"ENST00000608703",2,1909,"MSTRG.12884","HSPA1A","GO:0010628(positive regulation of gene expression);GO:0048471(perinuclear region of cytoplasm);GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016607(nuclear speck);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0030529(intracellular ribonucleoprotein complex);GO:0005829(cytosol);GO:0005783(endoplasmic reticulum);GO:0005739(mitochondrion);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0005925(focal adhesion);GO:0005813(centrosome);GO:0005815(microtubule organizing center);GO:0005576(extracellular region);GO:0046718(viral entry into host cell);GO:0006986(response to unfolded protein);GO:0005654(nucleoplasm);GO:0045296(cadherin binding);GO:0070062(extracellular exosome);GO:0050821(protein stabilization);GO:0005814(centriole);GO:0008285(negative regulation of cell proliferation);GO:0072562(blood microparticle);GO:0043488(regulation of mRNA stability);GO:0043234(protein complex);GO:0005102(receptor binding);GO:0043312(neutrophil degranulation);GO:0047485(protein N-terminus binding);GO:0043066(negative regulation of apoptotic process);GO:0051092(positive regulation of NF-kappaB transcription factor activity);GO:0030308(negative regulation of cell growth);GO:1904813(ficolin-1-rich granule lumen);GO:0031982(vesicle);GO:0051082(unfolded protein binding);GO:0019899(enzyme binding);GO:2001240(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand);GO:0031625(ubiquitin protein ligase binding);GO:0001618(virus receptor activity);GO:0030512(negative regulation of transforming growth factor beta receptor signaling pathway);GO:0016235(aggresome);GO:0000151(ubiquitin ligase complex);GO:0042826(histone deacetylase binding);GO:1900034(regulation of cellular response to heat);GO:0034599(cellular response to oxidative stress);GO:0034605(cellular response to heat);GO:0060548(negative regulation of cell death);GO:1901673(regulation of mitotic spindle assembly);GO:1902236(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway);GO:0042623(ATPase activity, coupled);GO:0001664(G-protein coupled receptor binding);GO:0042026(protein refolding);GO:0032436(positive regulation of proteasomal ubiquitin-dependent protein catabolic process);GO:0031072(heat shock protein binding);GO:0090084(negative regulation of inclusion body assembly);GO:0097718(disordered domain specific binding);GO:0006402(mRNA catabolic process);GO:0001106(RNA polymerase II transcription corepressor activity);GO:0016887(ATPase activity);GO:0097201(negative regulation of transcription from RNA polymerase II promoter in response to stress);GO:0032757(positive regulation of interleukin-8 production);GO:0046034(ATP metabolic process);GO:0031396(regulation of protein ubiquitination);GO:0051131(chaperone-mediated protein complex assembly);GO:0031249(denatured protein binding);GO:0044183(protein binding involved in protein folding);GO:0055131(C3HC4-type RING finger domain binding);GO:0031397(negative regulation of protein ubiquitination);GO:0070370(cellular heat acclimation);GO:0070434(positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway);GO:0090063(positive regulation of microtubule nucleation);GO:1901029(negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway);GO:1902380(positive regulation of endoribonuclease activity);GO:1903265(positive regulation of tumor necrosis factor-mediated signaling pathway);GO:1904722(positive regulation of mRNA endonucleolytic cleavage involved in unfolded protein response);GO:0016234(inclusion body)","03040(Spliceosome);04141(Protein processing in endoplasmic reticulum);04010(MAPK signaling pathway);04144(Endocytosis);04612(Antigen processing and presentation);04915(Estrogen signaling pathway);04213(Longevity regulating pathway - multiple species);05020(Prion diseases);05134(Legionellosis);05162(Measles);05164(Influenza A);05169(Epstein-Barr virus infection);05145(Toxoplasmosis)","NA","NA","heat shock protein family A (Hsp70) member 1A [Source:HGNC Symbol;Acc:HGNC:5232]",{"v":9.931345,"d":"9.93"},{"v":0.420781,"d":"0.42"},{"v":23.6021707253892,"d":"23.60"},{"v":4.5608476473023,"d":"4.56"},{"v":1.19438343464733e-08,"d":"0.00"},{"v":3.17381261361338e-06,"d":"0.00"},"up","yes"]
[61588,"j","chr15","+",42495614,42533054,"MSTRG.5013.8",9,2444,"MSTRG.5013","SNAP23","NA","NA","NA","NA","NA",{"v":2.726065,"d":"2.73"},{"v":45.566662,"d":"45.57"},{"v":0.059825865673461,"d":"0.06"},{"v":-4.06308682222702,"d":"-4.06"},{"v":1.20293079654843e-08,"d":"0.00"},{"v":3.17381261361338e-06,"d":"0.00"},"down","yes"]
[168221,0,"chr6","-",108212005,108261244,"ENST00000349379",4,890,"MSTRG.13196","SNX3","GO:0006810(transport);GO:0015031(protein transport);GO:0005829(cytosol);GO:0005515(protein binding);GO:0031410(cytoplasmic vesicle);GO:0035091(phosphatidylinositol binding);GO:0008289(lipid binding);GO:0005768(endosome);GO:0070062(extracellular exosome);GO:0010314(phosphatidylinositol-5-phosphate binding);GO:0032266(phosphatidylinositol-3-phosphate binding);GO:0080025(phosphatidylinositol-3,5-bisphosphate binding);GO:0010008(endosome membrane);GO:0016579(protein deubiquitination);GO:0005769(early endosome);GO:0019898(extrinsic component of membrane);GO:0031901(early endosome membrane);GO:0019903(protein phosphatase binding);GO:0030136(clathrin-coated vesicle);GO:0051224(negative regulation of protein transport);GO:0005737(cytoplasm);GO:0046597(negative regulation of viral entry into host cell);GO:0016055(Wnt signaling pathway);GO:0042177(negative regulation of protein catabolic process);GO:0010324(membrane invagination);GO:0010976(positive regulation of neuron projection development);GO:0032009(early phagosome);GO:0030904(retromer complex);GO:0070273(phosphatidylinositol-4-phosphate binding);GO:0009617(response to bacterium);GO:0022615(protein to membrane docking);GO:0030111(regulation of Wnt signaling pathway);GO:0050765(negative regulation of phagocytosis);GO:0070676(intralumenal vesicle formation);GO:2000642(negative regulation of early endosome to late endosome transport);GO:0045335(phagocytic vesicle)","04144(Endocytosis)","K17918","NA","sorting nexin 3 [Source:HGNC Symbol;Acc:HGNC:11174]",{"v":0.891375,"d":"0.89"},{"v":16.143311,"d":"16.14"},{"v":0.0552163679433544,"d":"0.06"},{"v":-4.17876019722081,"d":"-4.18"},{"v":1.25876882211597E-8,"d":"0.00"},{"v":3.27743650684616e-06,"d":"0.00"},"down","yes"]
[118461,"j","chr2","-",207074137,207167257,"MSTRG.9383.1",5,8241,"MSTRG.9383","KLF7","NA","NA","NA","NA","NA",{"v":4.68854,"d":"4.69"},{"v":0.211154,"d":"0.21"},{"v":22.2043626926319,"d":"22.20"},{"v":4.47277125869974,"d":"4.47"},{"v":1.45172866210028E-8,"d":"0.00"},{"v":3.73075412540784e-06,"d":"0.00"},"up","yes"]
[200535,"j","chrX","-",149478766,149505327,"MSTRG.15474.2",10,5926,"MSTRG.15474","IDS","NA","NA","NA","NA","NA",{"v":51.087563,"d":"51.09"},{"v":2.398923,"d":"2.40"},{"v":21.2960411818137,"d":"21.30"},{"v":4.41251336110428,"d":"4.41"},{"v":1.51913285452521e-08,"d":"0.00"},{"v":3.81670502864876e-06,"d":"0.00"},"up","yes"]
[6021,0,"chr1","-",51789196,51878040,"ENST00000539524",33,3417,"MSTRG.561","NRDC","GO:0046872(metal ion binding);GO:0003824(catalytic activity);GO:0016787(hydrolase activity);GO:0005829(cytosol);GO:0005515(protein binding);GO:0008233(peptidase activity);GO:0006508(proteolysis);GO:0004222(metalloendopeptidase activity);GO:0008237(metallopeptidase activity);GO:0008283(cell proliferation);GO:0009986(cell surface);GO:0016477(cell migration);GO:0048408(epidermal growth factor binding);GO:0007528(neuromuscular junction development);GO:0051044(positive regulation of membrane protein ectodomain proteolysis);GO:0052548(regulation of endopeptidase activity);GO:0005739(mitochondrion)","NA","NA","NA","nardilysin convertase [Source:HGNC Symbol;Acc:HGNC:7995]",{"v":24.277561,"d":"24.28"},{"v":1.123424,"d":"1.12"},{"v":21.6103278904492,"d":"21.61"},{"v":4.4336490570587,"d":"4.43"},{"v":1.52375023884805e-08,"d":"0.00"},{"v":3.81670502864876e-06,"d":"0.00"},"up","yes"]
[141628,0,"chr3","+",149812770,149962122,"ENST00000344229",11,2866,"MSTRG.11261","RNF13","GO:0005634(nucleus);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0043231(intracellular membrane-bounded organelle);GO:0046872(metal ion binding);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0016740(transferase activity);GO:0016567(protein ubiquitination);GO:0005794(Golgi apparatus);GO:0005765(lysosomal membrane);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005515(protein binding);GO:0000139(Golgi membrane);GO:0005764(lysosome);GO:0005768(endosome);GO:0031902(late endosome membrane);GO:0005637(nuclear inner membrane);GO:0004842(ubiquitin-protein transferase activity);GO:0051865(protein autoubiquitination);GO:0061630(ubiquitin protein ligase activity)","NA","NA","NA","ring finger protein 13 [Source:HGNC Symbol;Acc:HGNC:10057]",{"v":9.151557,"d":"9.15"},{"v":0.408865,"d":"0.41"},{"v":22.3828329644259,"d":"22.38"},{"v":4.48432074268817,"d":"4.48"},{"v":1.61336929380294e-08,"d":"0.00"},{"v":3.99066894822157e-06,"d":"0.00"},"up","yes"]
[74354,0,"chr16","+",67192185,67198917,"ENST00000567007",8,2615,"MSTRG.6004","E2F4","GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0046983(protein dimerization activity);GO:0006355(regulation of transcription, DNA-templated);GO:0006366(transcription from RNA polymerase II promoter);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0005515(protein binding);GO:0007049(cell cycle);GO:0005667(transcription factor complex);GO:0000278(mitotic cell cycle);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:0006977(DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0030030(cell projection organization);GO:0044458(motile cilium assembly);GO:0098534(centriole assembly);GO:1903251(multi-ciliated epithelial cell differentiation);GO:0019904(protein domain specific binding);GO:0008134(transcription factor binding);GO:0000790(nuclear chromatin);GO:0001077(transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:1990841(promoter-specific chromatin binding);GO:0001228(transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding);GO:0000083(regulation of transcription involved in G1/S transition of mitotic cell cycle);GO:0002064(epithelial cell development);GO:0006884(cell volume homeostasis);GO:0008015(blood circulation);GO:0008361(regulation of cell size);GO:0009887(animal organ morphogenesis);GO:0042127(regulation of cell proliferation);GO:0060271(cilium assembly)","04350(TGF-beta signaling pathway);04110(Cell cycle);04218(Cellular senescence)","NA","NA","E2F transcription factor 4 [Source:HGNC Symbol;Acc:HGNC:3118]",{"v":0.333717,"d":"0.33"},{"v":5.834458,"d":"5.83"},{"v":0.0571976008739801,"d":"0.06"},{"v":-4.12790155465567,"d":"-4.13"},{"v":1.66031068853379e-08,"d":"0.00"},{"v":4.05607751909958E-6,"d":"0.00"},"down","yes"]
[169643,"j","chr6","+",138404433,138422108,"MSTRG.13303.4",5,7668,"MSTRG.13303","HEBP2","NA","NA","NA","NA","NA",{"v":7.184891,"d":"7.18"},{"v":0.333482,"d":"0.33"},{"v":21.5450639014999,"d":"21.55"},{"v":4.42928547229785,"d":"4.43"},{"v":1.71891876410458E-8,"d":"0.00"},{"v":4.14804445171969e-06,"d":"0.00"},"up","yes"]
[5052,0,"chr1","+",43389895,43451152,"ENST00000634258",72,11045,"MSTRG.491","SZT2","GO:0016020(membrane);GO:0005765(lysosomal membrane);GO:0005764(lysosome);GO:0005777(peroxisome);GO:1904262(negative regulation of TORC1 signaling);GO:0003674(molecular_function);GO:0070062(extracellular exosome);GO:0061700(GATOR2 complex);GO:0042149(cellular response to glucose starvation);GO:0061462(protein localization to lysosome);GO:0034198(cellular response to amino acid starvation);GO:0007417(central nervous system development);GO:0009791(post-embryonic development);GO:1990130(GATOR1 complex);GO:0021540(corpus callosum morphogenesis);GO:1901668(regulation of superoxide dismutase activity);GO:0140007(KICSTOR complex);GO:0031667(response to nutrient levels);GO:0043473(pigmentation)","NA","NA","NA","SZT2, KICSTOR complex subunit [Source:HGNC Symbol;Acc:HGNC:29040]",{"v":3.61605,"d":"3.62"},{"v":0.168141,"d":"0.17"},{"v":21.5060574160972,"d":"21.51"},{"v":4.42667116276398,"d":"4.43"},{"v":1.82163154416453e-08,"d":"0.00"},{"v":4.34294518023226e-06,"d":"0.00"},"up","yes"]
[112112,"j","chr2","-",88846694,88947863,"MSTRG.8934.18",5,1014,"MSTRG.8934","IGKV1-5","NA","NA","NA","NA","NA",{"v":2.12058,"d":"2.12"},{"v":34.430725,"d":"34.43"},{"v":0.061589757404179,"d":"0.06"},{"v":-4.02116574422562,"d":"-4.02"},{"v":1.85096610391289e-08,"d":"0.00"},{"v":4.36034729336051e-06,"d":"0.00"},"down","yes"]
[101794,0,"chr19","+",41265122,41307019,"ENST00000263367",15,2952,"MSTRG.8172","HNRNPUL1","GO:0006396(RNA processing);GO:0005654(nucleoplasm);GO:0009615(response to virus);GO:0003723(RNA binding);GO:0005634(nucleus);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0019013(viral nucleocapsid);GO:0030529(intracellular ribonucleoprotein complex);GO:0005515(protein binding);GO:0019899(enzyme binding);GO:0000398(mRNA splicing, via spliceosome)","05164(Influenza A)","K15047","NA","heterogeneous nuclear ribonucleoprotein U like 1 [Source:HGNC Symbol;Acc:HGNC:17011]",{"v":7.886171,"d":"7.89"},{"v":0.355686,"d":"0.36"},{"v":22.171721687106,"d":"22.17"},{"v":4.47064889815565,"d":"4.47"},{"v":1.88472422610753e-08,"d":"0.00"},{"v":4.38763799837834e-06,"d":"0.00"},"up","yes"]
[185818,0,"chr8","+",97644546,97725243,"ENST00000519934",11,2184,"MSTRG.14475","MTDH","GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0043066(negative regulation of apoptotic process);GO:0005783(endoplasmic reticulum);GO:0001650(fibrillar center);GO:0005789(endoplasmic reticulum membrane);GO:0005515(protein binding);GO:0048471(perinuclear region of cytoplasm);GO:0030054(cell junction);GO:0045766(positive regulation of angiogenesis);GO:0043123(positive regulation of I-kappaB kinase/NF-kappaB signaling);GO:0070830(bicellular tight junction assembly);GO:0005730(nucleolus);GO:0005923(bicellular tight junction);GO:0016324(apical plasma membrane);GO:0046581(intercellular canaliculus);GO:0003713(transcription coactivator activity);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0010508(positive regulation of autophagy);GO:0031965(nuclear membrane);GO:0051092(positive regulation of NF-kappaB transcription factor activity);GO:0051897(positive regulation of protein kinase B signaling);GO:0051059(NF-kappaB binding);GO:0003725(double-stranded RNA binding);GO:0016604(nuclear body);GO:0031663(lipopolysaccharide-mediated signaling pathway);GO:0001085(RNA polymerase II transcription factor binding)","NA","NA","NA","metadherin [Source:HGNC Symbol;Acc:HGNC:29608]",{"v":9.404182,"d":"9.40"},{"v":0.433014,"d":"0.43"},{"v":21.717962929605,"d":"21.72"},{"v":4.44081688453146,"d":"4.44"},{"v":2.34455060450708E-8,"d":"0.00"},{"v":5.3946473676728e-06,"d":"0.00"},"up","yes"]
[55224,0,"chr14","+",55271303,55353609,"ENST00000313833",2,3464,"MSTRG.4412","FBXO34","GO:0005515(protein binding)","NA","NA","NA","F-box protein 34 [Source:HGNC Symbol;Acc:HGNC:20201]",{"v":0.35222,"d":"0.35"},{"v":5.652455,"d":"5.65"},{"v":0.0623127472929904,"d":"0.06"},{"v":-4.00432886480491,"d":"-4.00"},{"v":2.57074037394305E-8,"d":"0.00"},{"v":5.84710465742357e-06,"d":"0.00"},"down","yes"]
[170562,0,"chr6","-",159679064,159693234,"ENST00000367055",6,990,"MSTRG.13403","SOD2","GO:0046872(metal ion binding);GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0004784(superoxide dismutase activity);GO:0006801(superoxide metabolic process);GO:0003677(DNA binding);GO:0019825(oxygen binding);GO:0019899(enzyme binding);GO:0030145(manganese ion binding);GO:0042802(identical protein binding);GO:0000302(response to reactive oxygen species);GO:0000303(response to superoxide);GO:0001306(age-dependent response to oxidative stress);GO:0001666(response to hypoxia);GO:0001836(release of cytochrome c from mitochondria);GO:0001889(liver development);GO:0003032(detection of oxygen);GO:0003069(acetylcholine-mediated vasodilation involved in regulation of systemic arterial blood pressure);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0006749(glutathione metabolic process);GO:0006979(response to oxidative stress);GO:0007005(mitochondrion organization);GO:0007507(heart development);GO:0007568(aging);GO:0007626(locomotory behavior);GO:0008217(regulation of blood pressure);GO:0008630(intrinsic apoptotic signaling pathway in response to DNA damage);GO:0008631(intrinsic apoptotic signaling pathway in response to oxidative stress);GO:0008637(apoptotic mitochondrial changes);GO:0009314(response to radiation);GO:0009409(response to cold);GO:0009791(post-embryonic development);GO:0010042(response to manganese ion);GO:0010043(response to zinc ion);GO:0010269(response to selenium ion);GO:0010332(response to gamma radiation);GO:0014823(response to activity);GO:0019430(removal of superoxide radicals);GO:0022904(respiratory electron transport chain);GO:0030097(hemopoiesis);GO:0031667(response to nutrient levels);GO:0032496(response to lipopolysaccharide);GO:0033591(response to L-ascorbic acid);GO:0034021(response to silicon dioxide);GO:0035900(response to isolation stress);GO:0035902(response to immobilization stress);GO:0042311(vasodilation);GO:0042493(response to drug);GO:0042542(response to hydrogen peroxide);GO:0042554(superoxide anion generation);GO:0042743(hydrogen peroxide metabolic process);GO:0043066(negative regulation of apoptotic process);GO:0045429(positive regulation of nitric oxide biosynthetic process);GO:0045599(negative regulation of fat cell differentiation);GO:0046686(response to cadmium ion);GO:0048147(negative regulation of fibroblast proliferation);GO:0048666(neuron development);GO:0048678(response to axon injury);GO:0048773(erythrophore differentiation);GO:0050665(hydrogen peroxide biosynthetic process);GO:0050790(regulation of catalytic activity);GO:0051260(protein homooligomerization);GO:0051602(response to electrical stimulus);GO:0051881(regulation of mitochondrial membrane potential);GO:0055072(iron ion homeostasis);GO:0055093(response to hyperoxia);GO:0071000(response to magnetism);GO:0071361(cellular response to ethanol);GO:0005737(cytoplasm);GO:0005739(mitochondrion);GO:0005743(mitochondrial inner membrane);GO:0042645(mitochondrial nucleoid);GO:0043209(myelin sheath);GO:0008285(negative regulation of cell proliferation);GO:0030335(positive regulation of cell migration);GO:0005759(mitochondrial matrix);GO:0070062(extracellular exosome);GO:0035722(interleukin-12-mediated signaling pathway);GO:0051289(protein homotetramerization);GO:0034599(cellular response to oxidative stress);GO:0043524(negative regulation of neuron apoptotic process);GO:1902176(negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway);GO:0001315(age-dependent response to reactive oxygen species);GO:0032364(oxygen homeostasis)","04068(FoxO signaling pathway);04146(Peroxisome);04211(Longevity regulating pathway - mammal);04213(Longevity regulating pathway - multiple species);05016(Huntington's disease)","K04564","EC:1.15.1.1","superoxide dismutase 2 [Source:HGNC Symbol;Acc:HGNC:11180]",{"v":18.740679,"d":"18.74"},{"v":281.368317,"d":"281.37"},{"v":0.0666055055516432,"d":"0.07"},{"v":-3.90821475566482,"d":"-3.91"},{"v":2.90487227019034e-08,"d":"0.00"},{"v":6.53200141846892e-06,"d":"0.00"},"down","yes"]
[1791,0,"chr1","+",13749403,13788079,"ENST00000413440",4,6175,"MSTRG.174","PRDM2","GO:0005634(nucleus);GO:0003676(nucleic acid binding);GO:0005794(Golgi apparatus);GO:0046872(metal ion binding);GO:0008168(methyltransferase activity);GO:0016740(transferase activity);GO:0032259(methylation);GO:0006355(regulation of transcription, DNA-templated);GO:0006366(transcription from RNA polymerase II promoter);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0008270(zinc ion binding);GO:0018024(histone-lysine N-methyltransferase activity);GO:0034968(histone lysine methylation);GO:0001228(transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0000977(RNA polymerase II regulatory region sequence-specific DNA binding);GO:0008340(determination of adult lifespan)","00310(Lysine degradation)","K11432","EC:2.1.1.43","PR/SET domain 2 [Source:HGNC Symbol;Acc:HGNC:9347]",{"v":0.205751,"d":"0.21"},{"v":3.242221,"d":"3.24"},{"v":0.0634598936963273,"d":"0.06"},{"v":-3.97801108522119,"d":"-3.98"},{"v":3.06427503412133e-08,"d":"0.00"},{"v":6.8130195927183e-06,"d":"0.00"},"down","yes"]
[12946,"j","chr1","+",161505430,161608794,"MSTRG.1158.6",8,9988,"MSTRG.1158","FCGR2A","NA","NA","NA","NA","NA",{"v":0.276015,"d":"0.28"},{"v":4.201521,"d":"4.20"},{"v":0.0656940665059154,"d":"0.07"},{"v":-3.92809311769073,"d":"-3.93"},{"v":3.14629716406022E-8,"d":"0.00"},{"v":6.89244617968318e-06,"d":"0.00"},"down","yes"]
[52775,"j","chr14","+",22112342,22552137,"MSTRG.4204.2",7,1428,"MSTRG.4204","TRAC","NA","NA","NA","NA","NA",{"v":0.599663,"d":"0.60"},{"v":9.661183,"d":"9.66"},{"v":0.0620693138718105,"d":"0.06"},{"v":-4.00997599164375,"d":"-4.01"},{"v":3.16966142283793e-08,"d":"0.00"},{"v":6.89244617968318e-06,"d":"0.00"},"down","yes"]
[9675,0,"chr1","+",117605934,117628372,"ENST00000369448",2,5751,"MSTRG.837","FAM46C","GO:0005515(protein binding)","NA","NA","NA","family with sequence similarity 46 member C [Source:HGNC Symbol;Acc:HGNC:24712]",{"v":5.604013,"d":"5.60"},{"v":0.276823,"d":"0.28"},{"v":20.2440295784671,"d":"20.24"},{"v":4.33942458226388,"d":"4.34"},{"v":3.27919917366459E-8,"d":"0.00"},{"v":7.05312970092118e-06,"d":"0.00"},"up","yes"]
[35728,0,"chr11","+",118436513,118523917,"ENST00000389506",36,13655,"MSTRG.2908","KMT2A","GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0005634(nucleus);GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0008168(methyltransferase activity);GO:0016740(transferase activity);GO:0032259(methylation);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0016569(covalent chromatin modification);GO:0003677(DNA binding);GO:0042803(protein homodimerization activity);GO:0005515(protein binding);GO:0048511(rhythmic process);GO:0006915(apoptotic process);GO:0018024(histone-lysine N-methyltransferase activity);GO:0045893(positive regulation of transcription, DNA-templated);GO:0042802(identical protein binding);GO:1902036(regulation of hematopoietic stem cell differentiation);GO:0044212(transcription regulatory region DNA binding);GO:0006366(transcription from RNA polymerase II promoter);GO:0071339(MLL1 complex);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0032922(circadian regulation of gene expression);GO:0001046(core promoter sequence-specific DNA binding);GO:0042800(histone methyltransferase activity (H3-K4 specific));GO:0045652(regulation of megakaryocyte differentiation);GO:0051568(histone H3-K4 methylation);GO:2000615(regulation of histone H3-K9 acetylation);GO:0006461(protein complex assembly);GO:0035097(histone methyltransferase complex);GO:0070577(lysine-acetylated histone binding);GO:0043984(histone H4-K16 acetylation);GO:0051571(positive regulation of histone H3-K4 methylation);GO:0035162(embryonic hemopoiesis);GO:0003680(AT DNA binding);GO:0032411(positive regulation of transporter activity);GO:0003682(chromatin binding);GO:0045322(unmethylated CpG binding);GO:0006306(DNA methylation);GO:0008285(negative regulation of cell proliferation);GO:0008542(visual learning);GO:0009416(response to light stimulus);GO:0009791(post-embryonic development);GO:0009952(anterior/posterior pattern specification);GO:0010468(regulation of gene expression);GO:0018026(peptidyl-lysine monomethylation);GO:0035640(exploration behavior);GO:0035864(response to potassium ion);GO:0044648(histone H3-K4 dimethylation);GO:0048172(regulation of short-term neuronal synaptic plasticity);GO:0048536(spleen development);GO:0048873(homeostasis of number of cells within a tissue);GO:0050890(cognition);GO:0051569(regulation of histone H3-K4 methylation);GO:0051899(membrane depolarization);GO:0060216(definitive hemopoiesis);GO:0071440(regulation of histone H3-K14 acetylation);GO:0080182(histone H3-K4 trimethylation);GO:1901674(regulation of histone H3-K27 acetylation);GO:2001040(positive regulation of cellular response to drug)","00310(Lysine degradation);05202(Transcriptional misregulation in cancers)","K09186","EC:2.1.1.43","lysine methyltransferase 2A [Source:HGNC Symbol;Acc:HGNC:7132]",{"v":5.375746,"d":"5.38"},{"v":0.2705,"d":"0.27"},{"v":19.8733678373383,"d":"19.87"},{"v":4.3127644742947,"d":"4.31"},{"v":3.36451026891139e-08,"d":"0.00"},{"v":7.15880959152888e-06,"d":"0.00"},"up","yes"]
[99413,0,"chr19","+",23827162,23828049,"ENST00000484897",1,888,"MSTRG.8049","RPSAP58","NA","NA","NA","NA","ribosomal protein SA pseudogene 58 [Source:HGNC Symbol;Acc:HGNC:36809]",{"v":3.475975,"d":"3.48"},{"v":52.241642,"d":"52.24"},{"v":0.0665364806106209,"d":"0.07"},{"v":-3.90971063163757,"d":"-3.91"},{"v":3.47219754153023e-08,"d":"0.00"},{"v":7.28311005361942e-06,"d":"0.00"},"down","yes"]
[44043,0,"chr12","+",66302545,66347645,"ENST00000247815",13,12866,"ENSG00000127311","HELB","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0016787(hydrolase activity);GO:0004003(ATP-dependent DNA helicase activity);GO:0004386(helicase activity);GO:0032508(DNA duplex unwinding);GO:0005694(chromosome);GO:0006281(DNA repair);GO:0006974(cellular response to DNA damage stimulus);GO:0006260(DNA replication);GO:0006261(DNA-dependent DNA replication);GO:0006269(DNA replication, synthesis of RNA primer);GO:0003723(RNA binding);GO:0004004(ATP-dependent RNA helicase activity);GO:0035861(site of double-strand break);GO:0005662(DNA replication factor A complex);GO:2000042(negative regulation of double-strand break repair via homologous recombination);GO:0005658(alpha DNA polymerase:primase complex);GO:0043141(ATP-dependent 5'-3' DNA helicase activity);GO:0006396(RNA processing);GO:0017116(single-stranded DNA-dependent ATP-dependent DNA helicase activity);GO:1903775(regulation of DNA double-strand break processing)","NA","NA","NA","DNA helicase B [Source:HGNC Symbol;Acc:HGNC:17196]",{"v":1.997864,"d":"2.00"},{"v":0.097739,"d":"0.10"},{"v":20.4408066380871,"d":"20.44"},{"v":4.35338022412797,"d":"4.35"},{"v":3.49654060589168e-08,"d":"0.00"},{"v":7.28311005361942e-06,"d":"0.00"},"up","yes"]
[161618,0,"chr5","-",177502088,177508877,"ENST00000500323",4,2219,"MSTRG.12582","DOK3","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0005158(insulin receptor binding);GO:0043312(neutrophil degranulation);GO:0030667(secretory granule membrane);GO:0101003(ficolin-1-rich granule membrane)","NA","NA","NA","docking protein 3 [Source:HGNC Symbol;Acc:HGNC:24583]",{"v":0.454996,"d":"0.45"},{"v":7.050293,"d":"7.05"},{"v":0.0645357575919185,"d":"0.06"},{"v":-3.95375744774579,"d":"-3.95"},{"v":3.9858410950801e-08,"d":"0.00"},{"v":8.21581495723385e-06,"d":"0.00"},"down","yes"]
[34355,0,"chr11","+",95089810,95132645,"ENST00000278505",2,4687,"MSTRG.2800","ENDOD1","GO:0003676(nucleic acid binding);GO:0016020(membrane);GO:0016787(hydrolase activity);GO:0046872(metal ion binding);GO:0090305(nucleic acid phosphodiester bond hydrolysis);GO:0005576(extracellular region);GO:0004519(endonuclease activity);GO:0004518(nuclease activity);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0002576(platelet degranulation)","NA","NA","NA","endonuclease domain containing 1 [Source:HGNC Symbol;Acc:HGNC:29129]",{"v":0.399185,"d":"0.40"},{"v":5.952888,"d":"5.95"},{"v":0.0670573677851826,"d":"0.07"},{"v":-3.89846033589734,"d":"-3.90"},{"v":4.20182159150504e-08,"d":"0.00"},{"v":8.57171604667028e-06,"d":"0.00"},"down","yes"]
[105417,0,"chr19","+",54200871,54207522,"ENST00000436445",6,752,"MSTRG.8410","RPS9","GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0006412(translation);GO:0030529(intracellular ribonucleoprotein complex);GO:0005622(intracellular);GO:0003735(structural constituent of ribosome);GO:0005840(ribosome);GO:0015935(small ribosomal subunit);GO:0005515(protein binding);GO:0022627(cytosolic small ribosomal subunit);GO:0019843(rRNA binding);GO:0005730(nucleolus);GO:0005925(focal adhesion);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0008284(positive regulation of cell proliferation);GO:0006413(translational initiation);GO:0006364(rRNA processing);GO:0000184(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay);GO:0019083(viral transcription);GO:0006614(SRP-dependent cotranslational protein targeting to membrane);GO:0045182(translation regulator activity);GO:0045903(positive regulation of translational fidelity)","03010(Ribosome)","K02997","NA","ribosomal protein S9 [Source:HGNC Symbol;Acc:HGNC:10442]",{"v":1.985863,"d":"1.99"},{"v":29.91427,"d":"29.91"},{"v":0.0663851399348873,"d":"0.07"},{"v":-3.91299585394854,"d":"-3.91"},{"v":4.60787641446121e-08,"d":"0.00"},{"v":9.30414882544474e-06,"d":"0.00"},"down","yes"]
[170228,0,"chr6","-",152121684,152637399,"ENST00000367255",146,27748,"MSTRG.13391","SYNE1","GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005654(nucleoplasm);GO:0031965(nuclear membrane);GO:0051015(actin filament binding);GO:0005794(Golgi apparatus);GO:0003779(actin binding);GO:0042803(protein homodimerization activity);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0034993(LINC complex);GO:0045211(postsynaptic membrane);GO:0030154(cell differentiation);GO:0007283(spermatogenesis);GO:0090286(cytoskeletal anchoring at nuclear membrane);GO:0005635(nuclear envelope);GO:0019899(enzyme binding);GO:0005730(nucleolus);GO:0007030(Golgi organization);GO:0030017(sarcomere);GO:0006997(nucleus organization);GO:0005521(lamin binding);GO:0090292(nuclear matrix anchoring at nuclear membrane);GO:0042692(muscle cell differentiation);GO:0005640(nuclear outer membrane);GO:0000932(P-body);GO:0008092(cytoskeletal protein binding)","NA","NA","NA","spectrin repeat containing nuclear envelope protein 1 [Source:HGNC Symbol;Acc:HGNC:17089]",{"v":1.580774,"d":"1.58"},{"v":0.081657,"d":"0.08"},{"v":19.358707765409,"d":"19.36"},{"v":4.27491074777581,"d":"4.27"},{"v":4.69063686727166e-08,"d":"0.00"},{"v":9.37558811409815e-06,"d":"0.00"},"up","yes"]
[121706,0,"chr20","+",3786772,3806121,"ENST00000344256",16,3071,"MSTRG.9573","CDC25B","GO:0005737(cytoplasm);GO:0016787(hydrolase activity);GO:0005622(intracellular);GO:0051301(cell division);GO:0004725(protein tyrosine phosphatase activity);GO:0006470(protein dephosphorylation);GO:0035335(peptidyl-tyrosine dephosphorylation);GO:0004721(phosphoprotein phosphatase activity);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0007049(cell cycle);GO:1902751(positive regulation of cell cycle G2/M phase transition);GO:0000922(spindle pole);GO:0005813(centrosome);GO:0005815(microtubule organizing center);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0019901(protein kinase binding);GO:0000086(G2/M transition of mitotic cell cycle);GO:0006468(protein phosphorylation);GO:0000278(mitotic cell cycle);GO:0032467(positive regulation of cytokinesis);GO:0008284(positive regulation of cell proliferation);GO:0045931(positive regulation of mitotic cell cycle);GO:0001556(oocyte maturation);GO:0007144(female meiosis I);GO:0045860(positive regulation of protein kinase activity);GO:0005634(nucleus)","04010(MAPK signaling pathway);04110(Cell cycle);04914(Progesterone-mediated oocyte maturation);05206(MicroRNAs in cancer)","K05866","EC:3.1.3.48","cell division cycle 25B [Source:HGNC Symbol;Acc:HGNC:1726]",{"v":5.359452,"d":"5.36"},{"v":0.265041,"d":"0.27"},{"v":20.2212186039141,"d":"20.22"},{"v":4.33779803677956,"d":"4.34"},{"v":4.82881209545148e-08,"d":"0.00"},{"v":9.55525337447939e-06,"d":"0.00"},"up","yes"]
[182689,0,"chr8","-",30063126,30082948,"ENST00000521265",6,1741,"MSTRG.14272","SARAF","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0006811(ion transport);GO:0006816(calcium ion transport);GO:0030176(integral component of endoplasmic reticulum membrane);GO:0005515(protein binding);GO:2001256(regulation of store-operated calcium entry)","NA","NA","NA","store-operated calcium entry associated regulatory factor [Source:HGNC Symbol;Acc:HGNC:28789]",{"v":0.429531,"d":"0.43"},{"v":6.505371,"d":"6.51"},{"v":0.0660271335793147,"d":"0.07"},{"v":-3.92079717385091,"d":"-3.92"},{"v":5.87931962245575e-08,"d":"0.00"},{"v":1.15188095731836e-05,"d":"0.00"},"down","yes"]
[99732,0,"chr19","+",33373330,33382686,"ENST00000284000",2,4109,"ENSG00000153879","CEBPG","GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0006355(regulation of transcription, DNA-templated);GO:0006366(transcription from RNA polymerase II promoter);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0005515(protein binding);GO:0006955(immune response);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0043565(sequence-specific DNA binding);GO:0008134(transcription factor binding);GO:0043433(negative regulation of sequence-specific DNA binding transcription factor activity);GO:0046982(protein heterodimerization activity);GO:0051091(positive regulation of sequence-specific DNA binding transcription factor activity);GO:0001077(transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0045078(positive regulation of interferon-gamma biosynthetic process);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0045739(positive regulation of DNA repair);GO:0001889(liver development);GO:0043388(positive regulation of DNA binding);GO:0030183(B cell differentiation);GO:0042267(natural killer cell mediated cytotoxicity);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:0003690(double-stranded DNA binding);GO:0042803(protein homodimerization activity);GO:0044377(RNA polymerase II core promoter proximal region sequence-specific DNA binding, bending);GO:0016071(mRNA metabolic process);GO:0043353(enucleate erythrocyte differentiation)","05152(Tuberculosis)","K10049","NA","CCAAT/enhancer binding protein gamma [Source:HGNC Symbol;Acc:HGNC:1837]",{"v":5.146363,"d":"5.15"},{"v":0.266021,"d":"0.27"},{"v":19.3457020310427,"d":"19.35"},{"v":4.27394117819559,"d":"4.27"},{"v":5.95430240278044e-08,"d":"0.00"},{"v":1.15513466613941e-05,"d":"0.00"},"up","yes"]
[19870,0,"chr10","-",43385617,43397346,"ENST00000544000",4,2676,"MSTRG.1667","HNRNPF","GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0006397(mRNA processing);GO:0008380(RNA splicing);GO:0005634(nucleus);GO:0016020(membrane);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0019013(viral nucleocapsid);GO:0030529(intracellular ribonucleoprotein complex);GO:0005515(protein binding);GO:0005681(spliceosomal complex);GO:0005886(plasma membrane);GO:0043484(regulation of RNA splicing);GO:0000398(mRNA splicing, via spliceosome);GO:0035722(interleukin-12-mediated signaling pathway);GO:0008543(fibroblast growth factor receptor signaling pathway);GO:0016070(RNA metabolic process);GO:0006396(RNA processing);GO:0071013(catalytic step 2 spliceosome);GO:0003727(single-stranded RNA binding);GO:0008134(transcription factor binding);GO:0017025(TBP-class protein binding)","NA","NA","NA","heterogeneous nuclear ribonucleoprotein F [Source:HGNC Symbol;Acc:HGNC:5039]",{"v":0.398264,"d":"0.40"},{"v":5.862006,"d":"5.86"},{"v":0.0679398826954459,"d":"0.07"},{"v":-3.87959746250322,"d":"-3.88"},{"v":6.05396549920753e-08,"d":"0.00"},{"v":1.16306669221669E-5,"d":"0.00"},"down","yes"]
[172517,"j","chr7","-",26190225,26200755,"MSTRG.13527.6",12,2744,"MSTRG.13527","HNRNPA2B1","NA","NA","NA","NA","NA",{"v":20.15913,"d":"20.16"},{"v":1.087824,"d":"1.09"},{"v":18.5316098927768,"d":"18.53"},{"v":4.21191631264962,"d":"4.21"},{"v":6.51906809484568E-8,"d":"0.00"},{"v":1.24037807173852E-5,"d":"0.00"},"up","yes"]
[66139,0,"chr15","+",88638743,88656483,"ENST00000306072",4,1856,"MSTRG.5390","ISG20","GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0016787(hydrolase activity);GO:0004527(exonuclease activity);GO:0004518(nuclease activity);GO:0002376(immune system process);GO:0045087(innate immune response);GO:0005730(nucleolus);GO:0006364(rRNA processing);GO:0051607(defense response to virus);GO:0030619(U1 snRNA binding);GO:0005654(nucleoplasm);GO:0090503(RNA phosphodiester bond hydrolysis, exonucleolytic);GO:0009615(response to virus);GO:0045071(negative regulation of viral genome replication);GO:0016605(PML body);GO:0008283(cell proliferation);GO:0006401(RNA catabolic process);GO:0060337(type I interferon signaling pathway);GO:0015030(Cajal body);GO:0000175(3'-5'-exoribonuclease activity);GO:0008310(single-stranded DNA 3'-5' exodeoxyribonuclease activity);GO:0008859(exoribonuclease II activity);GO:0030620(U2 snRNA binding);GO:0034511(U3 snoRNA binding);GO:0000738(DNA catabolic process, exonucleolytic)","NA","NA","NA","interferon stimulated exonuclease gene 20 [Source:HGNC Symbol;Acc:HGNC:6130]",{"v":29.2439,"d":"29.24"},{"v":1.588046,"d":"1.59"},{"v":18.4150207235811,"d":"18.42"},{"v":4.2028111156814,"d":"4.20"},{"v":6.95808787612138e-08,"d":"0.00"},{"v":1.31130136088276e-05,"d":"0.00"},"up","yes"]
[10701,0,"chr1","-",150996086,151006404,"ENST00000622754",11,2637,"MSTRG.937","MINDY1","GO:0004843(thiol-dependent ubiquitin-specific protease activity);GO:0016787(hydrolase activity);GO:0005515(protein binding);GO:0008233(peptidase activity);GO:0008234(cysteine-type peptidase activity);GO:0006508(proteolysis);GO:0036459(thiol-dependent ubiquitinyl hydrolase activity);GO:0008150(biological_process);GO:0070062(extracellular exosome);GO:1990380(Lys48-specific deubiquitinase activity);GO:0071108(protein K48-linked deubiquitination);GO:0036435(K48-linked polyubiquitin binding);GO:0016807(cysteine-type carboxypeptidase activity)","NA","NA","NA","MINDY lysine 48 deubiquitinase 1 [Source:HGNC Symbol;Acc:HGNC:25648]",{"v":6.859066,"d":"6.86"},{"v":0.359277,"d":"0.36"},{"v":19.091302810923,"d":"19.09"},{"v":4.2548436520412,"d":"4.25"},{"v":7.24652170800544e-08,"d":"0.00"},{"v":1.35277520337747E-5,"d":"0.00"},"up","yes"]
[3161,"j","chr1","+",26696007,26782102,"MSTRG.286.2",20,8598,"MSTRG.286","ARID1A","NA","NA","NA","NA","NA",{"v":9.361109,"d":"9.36"},{"v":0.520202,"d":"0.52"},{"v":17.995142271656,"d":"18.00"},{"v":4.16953560330734,"d":"4.17"},{"v":7.77932879452968e-08,"d":"0.00"},{"v":1.43866689893601E-5,"d":"0.00"},"up","yes"]
[1681,0,"chr1","+",12167003,12209228,"ENST00000492361",9,3583,"MSTRG.168","TNFRSF1B","GO:0071222(cellular response to lipopolysaccharide);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0006915(apoptotic process);GO:0006954(inflammatory response);GO:0006955(immune response);GO:0005887(integral component of plasma membrane);GO:0097190(apoptotic signaling pathway);GO:0033209(tumor necrosis factor-mediated signaling pathway);GO:0031625(ubiquitin protein ligase binding);GO:0043312(neutrophil degranulation);GO:0035579(specific granule membrane);GO:0005031(tumor necrosis factor-activated receptor activity);GO:0007275(multicellular organism development);GO:0042127(regulation of cell proliferation);GO:0043154(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process);GO:0051044(positive regulation of membrane protein ectodomain proteolysis);GO:0045121(membrane raft);GO:0007166(cell surface receptor signaling pathway);GO:0007568(aging);GO:0008630(intrinsic apoptotic signaling pathway in response to DNA damage);GO:0032496(response to lipopolysaccharide);GO:0050728(negative regulation of inflammatory response);GO:0050779(RNA destabilization);GO:0071363(cellular response to growth factor stimulus);GO:0097191(extrinsic apoptotic signaling pathway);GO:0005634(nucleus);GO:0030424(axon);GO:0043025(neuronal cell body);GO:0043196(varicosity);GO:0048471(perinuclear region of cytoplasm)","04668(TNF signaling pathway);04060(Cytokine-cytokine receptor interaction);04920(Adipocytokine signaling pathway);05014(Amyotrophic lateral sclerosis (ALS))","NA","NA","TNF receptor superfamily member 1B [Source:HGNC Symbol;Acc:HGNC:11917]",{"v":18.680225,"d":"18.68"},{"v":1.038158,"d":"1.04"},{"v":17.9936242845501,"d":"17.99"},{"v":4.16941389908234,"d":"4.17"},{"v":8.12897009428644e-08,"d":"0.00"},{"v":1.48940796505315E-5,"d":"0.00"},"up","yes"]
[131744,0,"chr22","+",41621350,41664039,"ENST00000359308",12,2709,"MSTRG.10518","XRCC6","GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0005634(nucleus);GO:0003723(RNA binding);GO:0016020(membrane);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0005654(nucleoplasm);GO:0016787(hydrolase activity);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0004003(ATP-dependent DNA helicase activity);GO:0004386(helicase activity);GO:0032508(DNA duplex unwinding);GO:0016829(lyase activity);GO:0005694(chromosome);GO:0003684(damaged DNA binding);GO:0005515(protein binding);GO:0003824(catalytic activity);GO:0008152(metabolic process);GO:0042162(telomeric DNA binding);GO:0000723(telomere maintenance);GO:0006303(double-strand break repair via nonhomologous end joining);GO:0043564(Ku70:Ku80 complex);GO:0006281(DNA repair);GO:0006310(DNA recombination);GO:0006974(cellular response to DNA damage stimulus);GO:0045893(positive regulation of transcription, DNA-templated);GO:0005730(nucleolus);GO:0005576(extracellular region);GO:0005829(cytosol);GO:0000784(nuclear chromosome, telomeric region);GO:0008022(protein C-terminus binding);GO:0043312(neutrophil degranulation);GO:0034774(secretory granule lumen);GO:1904813(ficolin-1-rich granule lumen);GO:0045892(negative regulation of transcription, DNA-templated);GO:0043234(protein complex);GO:0044212(transcription regulatory region DNA binding);GO:0000783(nuclear telomere cap complex);GO:0032481(positive regulation of type I interferon production);GO:0005667(transcription factor complex);GO:0032993(protein-DNA complex);GO:0051575(5'-deoxyribose-5-phosphate lyase activity);GO:0075713(establishment of integrated proviral latency);GO:0003691(double-stranded telomeric DNA binding);GO:0003690(double-stranded DNA binding);GO:0044877(macromolecular complex binding);GO:0006266(DNA ligation);GO:0045860(positive regulation of protein kinase activity);GO:0048660(regulation of smooth muscle cell proliferation);GO:0051290(protein heterotetramerization);GO:0071480(cellular response to gamma radiation);GO:0097680(double-strand break repair via classical nonhomologous end joining);GO:0070419(nonhomologous end joining complex);GO:0007420(brain development);GO:0071475(cellular hyperosmotic salinity response);GO:0071481(cellular response to X-ray);GO:0005737(cytoplasm)","03450(Non-homologous end-joining)","NA","NA","X-ray repair cross complementing 6 [Source:HGNC Symbol;Acc:HGNC:4055]",{"v":20.914911,"d":"20.91"},{"v":1.163757,"d":"1.16"},{"v":17.9718884612509,"d":"17.97"},{"v":4.16767010810554,"d":"4.17"},{"v":8.22640842346628e-08,"d":"0.00"},{"v":1.49343275122524E-5,"d":"0.00"},"up","yes"]
[43169,"j","chr12","-",56639880,56646060,"MSTRG.3464.7",7,2055,"MSTRG.3464","ATP5B","NA","NA","NA","NA","NA",{"v":1.200757,"d":"1.20"},{"v":16.494816,"d":"16.49"},{"v":0.0727960227019204,"d":"0.07"},{"v":-3.7799965605728,"d":"-3.78"},{"v":8.43945699344488e-08,"d":"0.00"},{"v":1.51818159078443e-05,"d":"0.00"},"down","yes"]
[15078,0,"chr1","+",203799335,203854118,"ENST00000545588",17,7979,"MSTRG.1324","ZBED6","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0046983(protein dimerization activity);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0005730(nucleolus);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0000977(RNA polymerase II regulatory region sequence-specific DNA binding);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0045892(negative regulation of transcription, DNA-templated)","NA","NA","NA","zinc finger BED-type containing 6 [Source:HGNC Symbol;Acc:HGNC:33273]",{"v":0.266686,"d":"0.27"},{"v":3.653478,"d":"3.65"},{"v":0.0729951022012449,"d":"0.07"},{"v":-3.77605652396052,"d":"-3.78"},{"v":8.81728158976885e-08,"d":"0.00"},{"v":1.57185917205717e-05,"d":"0.00"},"down","yes"]
[23065,0,"chr10","+",102133030,102150325,"ENST00000278070",14,5330,"ENSG00000148840","PPRC1","GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0008134(transcription factor binding);GO:0003712(transcription cofactor activity);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0007005(mitochondrion organization);GO:0030374(ligand-dependent nuclear receptor transcription coactivator activity);GO:0001104(RNA polymerase II transcription cofactor activity);GO:0051091(positive regulation of sequence-specific DNA binding transcription factor activity);GO:1903506(regulation of nucleic acid-templated transcription)","NA","NA","NA","peroxisome proliferator-activated receptor gamma, coactivator-related 1 [Source:HGNC Symbol;Acc:HGNC:30025]",{"v":3.632014,"d":"3.63"},{"v":0.198936,"d":"0.20"},{"v":18.257198294929,"d":"18.26"},{"v":4.19039348473665,"d":"4.19"},{"v":9.82856669325623e-08,"d":"0.00"},{"v":1.73649712255495E-5,"d":"0.00"},"up","yes"]
[49013,0,"chr13","+",21176645,21179084,"ENST00000309594",2,2246,"MSTRG.3894","MRPL57","GO:0030529(intracellular ribonucleoprotein complex);GO:0005840(ribosome);GO:0005739(mitochondrion);GO:0003735(structural constituent of ribosome);GO:0032543(mitochondrial translation);GO:0006412(translation);GO:0005761(mitochondrial ribosome);GO:0005743(mitochondrial inner membrane);GO:0070125(mitochondrial translational elongation);GO:0070126(mitochondrial translational termination)","NA","NA","NA","mitochondrial ribosomal protein L57 [Source:HGNC Symbol;Acc:HGNC:14514]",{"v":0.554468,"d":"0.55"},{"v":7.602687,"d":"7.60"},{"v":0.0729305310083132,"d":"0.07"},{"v":-3.777333291364,"d":"-3.78"},{"v":1.0526661346851E-7,"d":"0.00"},{"v":1.84337676753529E-5,"d":"0.00"},"down","yes"]
[45128,0,"chr12","-",92140278,92145897,"ENST00000256015",2,4680,"MSTRG.3600","BTG1","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0006355(regulation of transcription, DNA-templated);GO:0005515(protein binding);GO:0008285(negative regulation of cell proliferation);GO:0019899(enzyme binding);GO:0030308(negative regulation of cell growth);GO:0016477(cell migration);GO:0003712(transcription cofactor activity);GO:0045766(positive regulation of angiogenesis);GO:0019900(kinase binding);GO:2000271(positive regulation of fibroblast apoptotic process);GO:0045663(positive regulation of myoblast differentiation);GO:0006479(protein methylation);GO:0045603(positive regulation of endothelial cell differentiation)","03018(RNA degradation)","K14443","NA","BTG anti-proliferation factor 1 [Source:HGNC Symbol;Acc:HGNC:1130]",{"v":1.517901,"d":"1.52"},{"v":19.807371,"d":"19.81"},{"v":0.0766331382392949,"d":"0.08"},{"v":-3.70588780238705,"d":"-3.71"},{"v":1.1050624431129E-7,"d":"0.00"},{"v":1.90658985592112E-5,"d":"0.00"},"down","yes"]
[110306,0,"chr2","-",64631621,64653913,"ENST00000313349",2,5549,"MSTRG.8762","SERTAD2","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0030308(negative regulation of cell growth);GO:0003713(transcription coactivator activity);GO:0045893(positive regulation of transcription, DNA-templated)","NA","NA","NA","SERTA domain containing 2 [Source:HGNC Symbol;Acc:HGNC:30784]",{"v":0.291381,"d":"0.29"},{"v":3.927752,"d":"3.93"},{"v":0.0741851827712137,"d":"0.07"},{"v":-3.75272512795787,"d":"-3.75"},{"v":1.10803433106392E-7,"d":"0.00"},{"v":1.90658985592112E-5,"d":"0.00"},"down","yes"]
[131364,0,"chr22","-",38734736,38755999,"ENST00000405018",18,4022,"MSTRG.10462","SUN2","GO:0005634(nucleus);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0031965(nuclear membrane);GO:0005515(protein binding);GO:0005639(integral component of nuclear inner membrane);GO:0034993(LINC complex);GO:0051321(meiotic cell cycle);GO:0008017(microtubule binding);GO:0042802(identical protein binding);GO:0005768(endosome);GO:0005637(nuclear inner membrane);GO:0030335(positive regulation of cell migration);GO:0010008(endosome membrane);GO:0007052(mitotic spindle organization);GO:0005635(nuclear envelope);GO:0005521(lamin binding);GO:0006998(nuclear envelope organization);GO:0043495(protein anchor);GO:0090286(cytoskeletal anchoring at nuclear membrane);GO:0090292(nuclear matrix anchoring at nuclear membrane);GO:0051642(centrosome localization);GO:0007097(nuclear migration);GO:0031022(nuclear migration along microfilament);GO:0021817(nucleokinesis involved in cell motility in cerebral cortex radial glia guided migration);GO:0000784(nuclear chromosome, telomeric region);GO:0000794(condensed nuclear chromosome)","NA","NA","NA","Sad1 and UNC84 domain containing 2 [Source:HGNC Symbol;Acc:HGNC:14210]",{"v":10.333386,"d":"10.33"},{"v":0.595965,"d":"0.60"},{"v":17.3389141979814,"d":"17.34"},{"v":4.11594165144971,"d":"4.12"},{"v":1.17907118290057E-7,"d":"0.00"},{"v":1.99832354572555e-05,"d":"0.00"},"up","yes"]
[141261,0,"chr3","-",142306607,142448062,"ENST00000264951",42,10143,"MSTRG.11245","XRN1","GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005829(cytosol);GO:0016787(hydrolase activity);GO:0003677(DNA binding);GO:0005886(plasma membrane);GO:0004527(exonuclease activity);GO:0004518(nuclease activity);GO:0005634(nucleus);GO:0005515(protein binding);GO:0000956(nuclear-transcribed mRNA catabolic process);GO:0043488(regulation of mRNA stability);GO:0070034(telomerase RNA binding);GO:0071044(histone mRNA catabolic process);GO:0071028(nuclear mRNA surveillance);GO:0090503(RNA phosphodiester bond hydrolysis, exonucleolytic);GO:0032211(negative regulation of telomere maintenance via telomerase);GO:0016075(rRNA catabolic process);GO:0051880(G-quadruplex DNA binding);GO:0004534(5'-3' exoribonuclease activity);GO:0002151(G-quadruplex RNA binding);GO:0008409(5'-3' exonuclease activity);GO:0017148(negative regulation of translation);GO:0033574(response to testosterone);GO:0071409(cellular response to cycloheximide);GO:1905795(cellular response to puromycin);GO:0000932(P-body);GO:0030425(dendrite);GO:0043025(neuronal cell body);GO:0045202(synapse);GO:0090305(nucleic acid phosphodiester bond hydrolysis)","03008(Ribosome biogenesis in eukaryotes);03018(RNA degradation)","K12618","EC:3.1.13.-","5'-3' exoribonuclease 1 [Source:HGNC Symbol;Acc:HGNC:30654]",{"v":1.949257,"d":"1.95"},{"v":0.108428,"d":"0.11"},{"v":17.9774320286273,"d":"17.98"},{"v":4.16811504988007,"d":"4.17"},{"v":1.18154363679952E-7,"d":"0.00"},{"v":1.99832354572555e-05,"d":"0.00"},"up","yes"]
[96867,0,"chr19","+",11597420,11619135,"ENST00000361113",4,2840,"MSTRG.7833","ZNF627","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0005622(intracellular);GO:0005515(protein binding)","NA","NA","NA","zinc finger protein 627 [Source:HGNC Symbol;Acc:HGNC:30570]",{"v":0.268451,"d":"0.27"},{"v":3.739393,"d":"3.74"},{"v":0.0717899937235803,"d":"0.07"},{"v":-3.80007341830837,"d":"-3.80"},{"v":1.20921881152673E-7,"d":"0.00"},{"v":2.02779846122804e-05,"d":"0.00"},"down","yes"]
[143989,0,"chr3","+",188225405,188890671,"ENST00000617246",11,18220,"ENSG00000145012","LPP","GO:0005829(cytosol);GO:0005925(focal adhesion);GO:0046872(metal ion binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0007155(cell adhesion);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0030054(cell junction);GO:0008150(biological_process)","NA","NA","NA","LIM domain containing preferred translocation partner in lipoma [Source:HGNC Symbol;Acc:HGNC:6679]",{"v":2.399279,"d":"2.40"},{"v":0.139175,"d":"0.14"},{"v":17.2392958505479,"d":"17.24"},{"v":4.10762894276743,"d":"4.11"},{"v":1.25212676282278E-7,"d":"0.00"},{"v":2.08210793132245e-05,"d":"0.00"},"up","yes"]
[121649,0,"chr20","-",3146519,3159897,"ENST00000380266",2,2874,"MSTRG.9567","FASTKD5","GO:0003723(RNA binding);GO:0006397(mRNA processing);GO:0004672(protein kinase activity);GO:0006468(protein phosphorylation);GO:0005739(mitochondrion);GO:0005515(protein binding);GO:0019843(rRNA binding);GO:0045333(cellular respiration);GO:0042645(mitochondrial nucleoid);GO:0035770(ribonucleoprotein granule);GO:0000963(mitochondrial RNA processing)","NA","NA","NA","FAST kinase domains 5 [Source:HGNC Symbol;Acc:HGNC:25790]",{"v":0.541268,"d":"0.54"},{"v":7.160325,"d":"7.16"},{"v":0.0755926581544832,"d":"0.08"},{"v":-3.72561006853567,"d":"-3.73"},{"v":1.2717141113331e-07,"d":"0.00"},{"v":2.09705656958828e-05,"d":"0.00"},"down","yes"]
[112123,"j","chr2","-",88846694,89268506,"MSTRG.8934.9",5,961,"MSTRG.8934","IGKV1-33","NA","NA","NA","NA","NA",{"v":6.952845,"d":"6.95"},{"v":89.099419,"d":"89.10"},{"v":0.0780346839298694,"d":"0.08"},{"v":-3.67974069129021,"d":"-3.68"},{"v":1.29320776226615e-07,"d":"0.00"},{"v":2.1148756363407E-5,"d":"0.00"},"down","yes"]
[37264,"j","chr12","+",752584,909436,"MSTRG.3007.4",27,8313,"MSTRG.3007","WNK1","NA","NA","NA","NA","NA",{"v":2.19902,"d":"2.20"},{"v":0.124374,"d":"0.12"},{"v":17.6807049704922,"d":"17.68"},{"v":4.14410389434276,"d":"4.14"},{"v":1.34610771940873E-7,"d":"0.00"},{"v":2.18334258620164e-05,"d":"0.00"},"up","yes"]
[162872,0,"chr6","-",11183298,11232682,"ENST00000379446",7,4536,"MSTRG.12678","NEDD9","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0007155(cell adhesion);GO:0005794(Golgi apparatus);GO:0051301(cell division);GO:0005886(plasma membrane);GO:0005856(cytoskeleton);GO:0042995(cell projection);GO:0005515(protein binding);GO:0007049(cell cycle);GO:0030054(cell junction);GO:0007229(integrin-mediated signaling pathway);GO:0005925(focal adhesion);GO:0005819(spindle);GO:0030027(lamellipodium);GO:0040008(regulation of growth);GO:0005938(cell cortex);GO:0007010(cytoskeleton organization);GO:0007165(signal transduction);GO:0051017(actin filament bundle assembly);GO:0000922(spindle pole)","NA","NA","NA","neural precursor cell expressed, developmentally down-regulated 9 [Source:HGNC Symbol;Acc:HGNC:7733]",{"v":3.010902,"d":"3.01"},{"v":0.169919,"d":"0.17"},{"v":17.7196311183564,"d":"17.72"},{"v":4.1472766655265,"d":"4.15"},{"v":1.52184224074559e-07,"d":"0.00"},{"v":2.44831010242877E-5,"d":"0.00"},"up","yes"]
[167603,0,"chr6","-",85607785,85642922,"ENST00000616122",11,6764,"MSTRG.13153","SYNCRIP","GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0006397(mRNA processing);GO:0008380(RNA splicing);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0030529(intracellular ribonucleoprotein complex);GO:0005783(endoplasmic reticulum);GO:0005515(protein binding);GO:0005681(spliceosomal complex);GO:0005654(nucleoplasm);GO:0043231(intracellular membrane-bounded organelle);GO:0006417(regulation of translation);GO:0071346(cellular response to interferon-gamma);GO:0016032(viral process);GO:0017148(negative regulation of translation);GO:0000398(mRNA splicing, via spliceosome);GO:0006396(RNA processing);GO:0071013(catalytic step 2 spliceosome);GO:0001649(osteoblast differentiation);GO:0070934(CRD-mediated mRNA stabilization);GO:0070937(CRD-mediated mRNA stability complex);GO:0071204(histone pre-mRNA 3'end processing complex);GO:0097452(GAIT complex);GO:0008143(poly(A) binding);GO:0019013(viral nucleocapsid)","NA","NA","NA","synaptotagmin binding cytoplasmic RNA interacting protein [Source:HGNC Symbol;Acc:HGNC:16918]",{"v":3.432886,"d":"3.43"},{"v":0.200845,"d":"0.20"},{"v":17.0922153899773,"d":"17.09"},{"v":4.09526749745983,"d":"4.10"},{"v":1.60171249815881E-7,"d":"0.00"},{"v":2.55602313819085e-05,"d":"0.00"},"up","yes"]
[194713,0,"chr9","-",135808487,135907224,"ENST00000389532",17,7696,"ENSG00000130559","CAMSAP1","GO:0005737(cytoplasm);GO:0005856(cytoskeleton);GO:0031175(neuron projection development);GO:0008017(microtubule binding);GO:0005874(microtubule);GO:0005516(calmodulin binding);GO:0007010(cytoskeleton organization);GO:0022604(regulation of cell morphogenesis);GO:0030507(spectrin binding)","NA","NA","NA","calmodulin regulated spectrin associated protein 1 [Source:HGNC Symbol;Acc:HGNC:19946]",{"v":2.544039,"d":"2.54"},{"v":0.147135,"d":"0.15"},{"v":17.2905087164849,"d":"17.29"},{"v":4.11190841105976,"d":"4.11"},{"v":1.67358602498103e-07,"d":"0.00"},{"v":2.64935362098598E-5,"d":"0.00"},"up","yes"]
[23161,0,"chr10","+",102743970,102816240,"ENST00000448841",4,4085,"MSTRG.1942","WBP1L","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005515(protein binding)","NA","NA","NA","WW domain binding protein 1 like [Source:HGNC Symbol;Acc:HGNC:23510]",{"v":21.57082,"d":"21.57"},{"v":1.328244,"d":"1.33"},{"v":16.2401034749639,"d":"16.24"},{"v":4.02148891967287,"d":"4.02"},{"v":1.87695616352357E-7,"d":"0.00"},{"v":2.94771496538131e-05,"d":"0.00"},"up","yes"]
[13834,0,"chr1","-",175156987,175192793,"ENST00000423313",4,4564,"MSTRG.1209","KIAA0040","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005515(protein binding)","NA","NA","NA","KIAA0040 [Source:HGNC Symbol;Acc:HGNC:28950]",{"v":29.666737,"d":"29.67"},{"v":1.863708,"d":"1.86"},{"v":15.9181250496322,"d":"15.92"},{"v":3.99259850985829,"d":"3.99"},{"v":2.15883369695636e-07,"d":"0.00"},{"v":3.36370088152539e-05,"d":"0.00"},"up","yes"]
[11830,"j","chr1","+",155688009,155739010,"MSTRG.1064.6",14,2305,"MSTRG.1064","DAP3","NA","NA","NA","NA","NA",{"v":7.449654,"d":"7.45"},{"v":0.448072,"d":"0.45"},{"v":16.6260199253691,"d":"16.63"},{"v":4.05537094053207,"d":"4.06"},{"v":2.32769891617402e-07,"d":"0.00"},{"v":3.59847704322277e-05,"d":"0.00"},"up","yes"]
[71306,0,"chr16","+",28711527,28735597,"ENST00000566866",20,2986,"MSTRG.5777","EIF3C","GO:0003723(RNA binding);GO:0005737(cytoplasm);GO:0003743(translation initiation factor activity);GO:0031369(translation initiation factor binding);GO:0001731(formation of translation preinitiation complex);GO:0006412(translation);GO:0006413(translational initiation);GO:0006446(regulation of translational initiation);GO:0005852(eukaryotic translation initiation factor 3 complex);GO:0016282(eukaryotic 43S preinitiation complex);GO:0033290(eukaryotic 48S preinitiation complex);GO:0005515(protein binding);GO:0005829(cytosol);GO:0045727(positive regulation of translation);GO:1902416(positive regulation of mRNA binding)","03013(RNA transport)","K03252","NA","eukaryotic translation initiation factor 3 subunit C [Source:HGNC Symbol;Acc:HGNC:3279]",{"v":4.77807,"d":"4.78"},{"v":0.28412,"d":"0.28"},{"v":16.8170843305646,"d":"16.82"},{"v":4.07185569426999,"d":"4.07"},{"v":2.41923337534224e-07,"d":"0.00"},{"v":3.70983304445703e-05,"d":"0.00"},"up","yes"]
[46296,0,"chr12","-",108645109,108731596,"ENST00000261401",11,3892,"MSTRG.3686","CORO1C","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0051015(actin filament binding);GO:0003779(actin binding);GO:0015629(actin cytoskeleton);GO:0005886(plasma membrane);GO:0030036(actin cytoskeleton organization);GO:0005856(cytoskeleton);GO:0042995(cell projection);GO:0005925(focal adhesion);GO:0005515(protein binding);GO:0030027(lamellipodium);GO:0090630(activation of GTPase activity);GO:0016328(lateral plasma membrane);GO:0007165(signal transduction);GO:0001933(negative regulation of protein phosphorylation);GO:0031982(vesicle);GO:0051895(negative regulation of focal adhesion assembly);GO:1900025(negative regulation of substrate adhesion-dependent cell spreading);GO:0001932(regulation of protein phosphorylation);GO:0051893(regulation of focal adhesion assembly);GO:0001755(neural crest cell migration);GO:0045184(establishment of protein localization);GO:0016600(flotillin complex);GO:0044387(negative regulation of protein kinase activity by regulation of protein phosphorylation);GO:0006909(phagocytosis);GO:2000394(positive regulation of lamellipodium morphogenesis);GO:0010633(negative regulation of epithelial cell migration);GO:0010632(regulation of epithelial cell migration);GO:0010762(regulation of fibroblast migration);GO:1900024(regulation of substrate adhesion-dependent cell spreading);GO:0048365(Rac GTPase binding);GO:1900027(regulation of ruffle assembly)","NA","NA","NA","coronin 1C [Source:HGNC Symbol;Acc:HGNC:2254]",{"v":1.585274,"d":"1.59"},{"v":18.903519,"d":"18.90"},{"v":0.0838613170383779,"d":"0.08"},{"v":-3.57585070194892,"d":"-3.58"},{"v":2.45249823496216e-07,"d":"0.00"},{"v":3.70983304445703e-05,"d":"0.00"},"down","yes"]
[197889,"j","chrX","+",65598663,65741931,"MSTRG.15335.7",14,4142,"MSTRG.15335","MSN","NA","NA","NA","NA","NA",{"v":2.174095,"d":"2.17"},{"v":25.830942,"d":"25.83"},{"v":0.0841663072140381,"d":"0.08"},{"v":-3.57061336911001,"d":"-3.57"},{"v":2.45597396818208E-7,"d":"0.00"},{"v":3.70983304445703e-05,"d":"0.00"},"down","yes"]
[119932,0,"chr2","-",230168918,230219950,"ENST00000258381",19,2426,"MSTRG.9473","SP110","GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0007165(signal transduction);GO:0016032(viral process);GO:0004871(signal transducer activity)","NA","NA","NA","SP110 nuclear body protein [Source:HGNC Symbol;Acc:HGNC:5401]",{"v":20.204004,"d":"20.20"},{"v":1.273715,"d":"1.27"},{"v":15.8622643212964,"d":"15.86"},{"v":3.98752682380652,"d":"3.99"},{"v":2.49595694170566e-07,"d":"0.00"},{"v":3.7416663607933e-05,"d":"0.00"},"up","yes"]
[98509,"j","chr19","+",18173160,18178175,"MSTRG.7986.10",8,1115,"MSTRG.7986","AC007192.1","NA","NA","NA","NA","NA",{"v":4.878796,"d":"4.88"},{"v":57.909737,"d":"57.91"},{"v":0.0842482845328757,"d":"0.08"},{"v":-3.56920887939845,"d":"-3.57"},{"v":2.57701880732458e-07,"d":"0.00"},{"v":3.83413895934877e-05,"d":"0.00"},"down","yes"]
[106380,0,"chr19","+",57769670,57780577,"ENST00000396154",3,2163,"MSTRG.8461","ZNF586","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0005622(intracellular);GO:0045892(negative regulation of transcription, DNA-templated)","NA","NA","NA","zinc finger protein 586 [Source:HGNC Symbol;Acc:HGNC:25949]",{"v":0.510957,"d":"0.51"},{"v":6.372252,"d":"6.37"},{"v":0.0801846819617303,"d":"0.08"},{"v":-3.64052953125629,"d":"-3.64"},{"v":2.61235237924818E-7,"d":"0.00"},{"v":3.85770364780321e-05,"d":"0.00"},"down","yes"]
[172824,"j","chr7","+",30135053,30162762,"MSTRG.13545.4",4,4304,"MSTRG.13545","MTURN","NA","NA","NA","NA","NA",{"v":6.623559,"d":"6.62"},{"v":0.417057,"d":"0.42"},{"v":15.8816636574857,"d":"15.88"},{"v":3.98929014242415,"d":"3.99"},{"v":2.90468309796141e-07,"d":"0.00"},{"v":4.25761993647855e-05,"d":"0.00"},"up","yes"]
[57935,0,"chr14","-",92939862,93115279,"ENST00000555495",9,3035,"MSTRG.4628","ITPK1","GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0016853(isomerase activity);GO:0016740(transferase activity);GO:0000287(magnesium ion binding);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0016787(hydrolase activity);GO:0005622(intracellular);GO:0016311(dephosphorylation);GO:0047325(inositol tetrakisphosphate 1-kinase activity);GO:0052725(inositol-1,3,4-trisphosphate 6-kinase activity);GO:0052726(inositol-1,3,4-trisphosphate 5-kinase activity);GO:0021915(neural tube development);GO:0032957(inositol trisphosphate metabolic process);GO:0016324(apical plasma membrane);GO:0005829(cytosol);GO:0007165(signal transduction);GO:0043647(inositol phosphate metabolic process);GO:0003824(catalytic activity);GO:0007596(blood coagulation);GO:0052659(inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity);GO:0052825(inositol-1,3,4,5,6-pentakisphosphate 1-phosphatase activity);GO:0052830(inositol-1,3,4,6-tetrakisphosphate 6-phosphatase activity);GO:0052831(inositol-1,3,4,6-tetrakisphosphate 1-phosphatase activity);GO:0052835(inositol-3,4,6-trisphosphate 1-kinase activity)","00562(Inositol phosphate metabolism);04070(Phosphatidylinositol signaling system)","K00913","EC:2.7.1.159;EC:2.7.1.134","inositol-tetrakisphosphate 1-kinase [Source:HGNC Symbol;Acc:HGNC:6177]",{"v":0.78934,"d":"0.79"},{"v":9.370007,"d":"9.37"},{"v":0.0842411323705521,"d":"0.08"},{"v":-3.56933136055259,"d":"-3.57"},{"v":2.95294941837058e-07,"d":"0.00"},{"v":4.2965414037292E-5,"d":"0.00"},"down","yes"]
[59522,"j","chr14","-",105851705,105865515,"MSTRG.4749.30",7,1794,"MSTRG.4749","IGHM","NA","NA","NA","NA","NA",{"v":1.778123,"d":"1.78"},{"v":20.960159,"d":"20.96"},{"v":0.0848334690590849,"d":"0.08"},{"v":-3.55922263112627,"d":"-3.56"},{"v":3.01802048370925e-07,"d":"0.00"},{"v":4.34084721170523e-05,"d":"0.00"},"down","yes"]
[170560,0,"chr6","-",159669057,159693328,"ENST00000538183",5,14266,"MSTRG.13403","SOD2","GO:0046872(metal ion binding);GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0004784(superoxide dismutase activity);GO:0006801(superoxide metabolic process);GO:0003677(DNA binding);GO:0019825(oxygen binding);GO:0019899(enzyme binding);GO:0030145(manganese ion binding);GO:0042802(identical protein binding);GO:0000302(response to reactive oxygen species);GO:0000303(response to superoxide);GO:0001306(age-dependent response to oxidative stress);GO:0001666(response to hypoxia);GO:0001836(release of cytochrome c from mitochondria);GO:0001889(liver development);GO:0003032(detection of oxygen);GO:0003069(acetylcholine-mediated vasodilation involved in regulation of systemic arterial blood pressure);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0006749(glutathione metabolic process);GO:0006979(response to oxidative stress);GO:0007005(mitochondrion organization);GO:0007507(heart development);GO:0007568(aging);GO:0007626(locomotory behavior);GO:0008217(regulation of blood pressure);GO:0008630(intrinsic apoptotic signaling pathway in response to DNA damage);GO:0008631(intrinsic apoptotic signaling pathway in response to oxidative stress);GO:0008637(apoptotic mitochondrial changes);GO:0009314(response to radiation);GO:0009409(response to cold);GO:0009791(post-embryonic development);GO:0010042(response to manganese ion);GO:0010043(response to zinc ion);GO:0010269(response to selenium ion);GO:0010332(response to gamma radiation);GO:0014823(response to activity);GO:0019430(removal of superoxide radicals);GO:0022904(respiratory electron transport chain);GO:0030097(hemopoiesis);GO:0031667(response to nutrient levels);GO:0032496(response to lipopolysaccharide);GO:0033591(response to L-ascorbic acid);GO:0034021(response to silicon dioxide);GO:0035900(response to isolation stress);GO:0035902(response to immobilization stress);GO:0042311(vasodilation);GO:0042493(response to drug);GO:0042542(response to hydrogen peroxide);GO:0042554(superoxide anion generation);GO:0042743(hydrogen peroxide metabolic process);GO:0043066(negative regulation of apoptotic process);GO:0045429(positive regulation of nitric oxide biosynthetic process);GO:0045599(negative regulation of fat cell differentiation);GO:0046686(response to cadmium ion);GO:0048147(negative regulation of fibroblast proliferation);GO:0048666(neuron development);GO:0048678(response to axon injury);GO:0048773(erythrophore differentiation);GO:0050665(hydrogen peroxide biosynthetic process);GO:0050790(regulation of catalytic activity);GO:0051260(protein homooligomerization);GO:0051602(response to electrical stimulus);GO:0051881(regulation of mitochondrial membrane potential);GO:0055072(iron ion homeostasis);GO:0055093(response to hyperoxia);GO:0071000(response to magnetism);GO:0071361(cellular response to ethanol);GO:0005737(cytoplasm);GO:0005739(mitochondrion);GO:0005743(mitochondrial inner membrane);GO:0042645(mitochondrial nucleoid);GO:0043209(myelin sheath);GO:0008285(negative regulation of cell proliferation);GO:0030335(positive regulation of cell migration);GO:0005759(mitochondrial matrix);GO:0070062(extracellular exosome);GO:0035722(interleukin-12-mediated signaling pathway);GO:0051289(protein homotetramerization);GO:0034599(cellular response to oxidative stress);GO:0043524(negative regulation of neuron apoptotic process);GO:1902176(negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway);GO:0001315(age-dependent response to reactive oxygen species);GO:0032364(oxygen homeostasis)","04068(FoxO signaling pathway);04146(Peroxisome);04211(Longevity regulating pathway - mammal);04213(Longevity regulating pathway - multiple species);05016(Huntington's disease)","K04564","EC:1.15.1.1","superoxide dismutase 2 [Source:HGNC Symbol;Acc:HGNC:11180]",{"v":9.721537,"d":"9.72"},{"v":0.635493,"d":"0.64"},{"v":15.2976303436859,"d":"15.30"},{"v":3.93523628661687,"d":"3.94"},{"v":3.02727367705337e-07,"d":"0.00"},{"v":4.34084721170523e-05,"d":"0.00"},"up","yes"]
[18205,0,"chr10","-",5765954,5813411,"ENST00000380181",10,1408,"MSTRG.1525","GDI2","GO:0003723(RNA binding);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0015031(protein transport);GO:0007264(small GTPase mediated signal transduction);GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0050790(regulation of catalytic activity);GO:0043547(positive regulation of GTPase activity);GO:0005515(protein binding);GO:0007165(signal transduction);GO:0005096(GTPase activator activity);GO:0005925(focal adhesion);GO:0005092(GDP-dissociation inhibitor activity);GO:0005576(extracellular region);GO:0005093(Rab GDP-dissociation inhibitor activity);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0051056(regulation of small GTPase mediated signal transduction);GO:0061024(membrane organization);GO:0043312(neutrophil degranulation);GO:0034774(secretory granule lumen);GO:0031982(vesicle);GO:0035578(azurophil granule lumen);GO:0031267(small GTPase binding);GO:0016192(vesicle-mediated transport)","NA","NA","NA","GDP dissociation inhibitor 2 [Source:HGNC Symbol;Acc:HGNC:4227]",{"v":2.597798,"d":"2.60"},{"v":30.294981,"d":"30.29"},{"v":0.0857501115448793,"d":"0.09"},{"v":-3.54371764181126,"d":"-3.54"},{"v":3.2525207755536e-07,"d":"0.00"},{"v":4.63027921630608E-5,"d":"0.00"},"down","yes"]
[153041,0,"chr5","+",446149,467285,"ENST00000315013",12,2682,"MSTRG.11953","EXOC3","GO:0006810(transport);GO:0005737(cytoplasm);GO:0015031(protein transport);GO:0006887(exocytosis);GO:0000145(exocyst);GO:0005794(Golgi apparatus);GO:0042995(cell projection);GO:0048471(perinuclear region of cytoplasm);GO:0030496(midbody);GO:0005515(protein binding);GO:0005829(cytosol);GO:0045296(cadherin binding);GO:0030426(growth cone);GO:0000149(SNARE binding);GO:0030667(secretory granule membrane);GO:0051601(exocyst localization)","NA","NA","NA","exocyst complex component 3 [Source:HGNC Symbol;Acc:HGNC:30378]",{"v":1.018471,"d":"1.02"},{"v":11.942405,"d":"11.94"},{"v":0.0852819009236414,"d":"0.09"},{"v":-3.55161659381476,"d":"-3.55"},{"v":3.29199655756016E-7,"d":"0.00"},{"v":4.65300199150003e-05,"d":"0.00"},"down","yes"]
[94328,0,"chr19","+",1438401,1440494,"ENST00000592623",3,873,"MSTRG.7611","RPS15","GO:0003723(RNA binding);GO:0030529(intracellular ribonucleoprotein complex);GO:0003735(structural constituent of ribosome);GO:0006412(translation);GO:0005840(ribosome);GO:0015935(small ribosomal subunit);GO:0005634(nucleus);GO:0016020(membrane);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0022627(cytosolic small ribosomal subunit);GO:0005654(nucleoplasm);GO:0005925(focal adhesion);GO:0006364(rRNA processing);GO:0042274(ribosomal small subunit biogenesis);GO:0000028(ribosomal small subunit assembly);GO:0005829(cytosol);GO:0006413(translational initiation);GO:0000184(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay);GO:0019083(viral transcription);GO:0001649(osteoblast differentiation);GO:0006614(SRP-dependent cotranslational protein targeting to membrane);GO:0000056(ribosomal small subunit export from nucleus)","03010(Ribosome)","NA","NA","ribosomal protein S15 [Source:HGNC Symbol;Acc:HGNC:10388]",{"v":5.956232,"d":"5.96"},{"v":67.85656,"d":"67.86"},{"v":0.087776804482868,"d":"0.09"},{"v":-3.51001643997629,"d":"-3.51"},{"v":3.73012727485712e-07,"d":"0.00"},{"v":5.21811452063753e-05,"d":"0.00"},"down","yes"]
[46244,0,"chr12","-",108288044,108339317,"ENST00000312143",3,5283,"MSTRG.3680","CMKLR1","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0004930(G-protein coupled receptor activity);GO:0007186(G-protein coupled receptor signaling pathway);GO:0005886(plasma membrane);GO:0004871(signal transducer activity);GO:0007165(signal transduction);GO:0070098(chemokine-mediated signaling pathway);GO:0006935(chemotaxis);GO:0005515(protein binding);GO:0032088(negative regulation of NF-kappaB transcription factor activity);GO:0005887(integral component of plasma membrane);GO:0006955(immune response);GO:0004872(receptor activity);GO:0001501(skeletal system development);GO:0004950(chemokine receptor activity);GO:0045600(positive regulation of fat cell differentiation);GO:0050848(regulation of calcium-mediated signaling);GO:0032695(negative regulation of interleukin-12 production);GO:0010759(positive regulation of macrophage chemotaxis)","NA","NA","NA","chemerin chemokine-like receptor 1 [Source:HGNC Symbol;Acc:HGNC:2121]",{"v":0.138284,"d":"0.14"},{"v":1.707129,"d":"1.71"},{"v":0.0810038374370068,"d":"0.08"},{"v":-3.62586593461448,"d":"-3.63"},{"v":3.74455357757494e-07,"d":"0.00"},{"v":5.21811452063753e-05,"d":"0.00"},"down","yes"]
[139917,0,"chr3","-",124965710,125055958,"ENST00000311127",17,9156,"ENSG00000173706","HEG1","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005509(calcium ion binding);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0007275(multicellular organism development);GO:0030054(cell junction);GO:0007507(heart development);GO:0007043(cell-cell junction assembly);GO:0001570(vasculogenesis);GO:0001701(in utero embryonic development);GO:0001885(endothelial cell development);GO:0001886(endothelial cell morphogenesis);GO:0001944(vasculature development);GO:0001945(lymph vessel development);GO:0003017(lymph circulation);GO:0003209(cardiac atrium morphogenesis);GO:0003222(ventricular trabecula myocardium morphogenesis);GO:0003281(ventricular septum development);GO:0009791(post-embryonic development);GO:0030324(lung development);GO:0035264(multicellular organism growth);GO:0045216(cell-cell junction organization);GO:0048845(venous blood vessel morphogenesis);GO:0050878(regulation of body fluid levels);GO:0055017(cardiac muscle tissue growth);GO:0060039(pericardium development);GO:0090271(positive regulation of fibroblast growth factor production);GO:0005911(cell-cell junction);GO:0009897(external side of plasma membrane);GO:0009986(cell surface)","NA","NA","NA","heart development protein with EGF like domains 1 [Source:HGNC Symbol;Acc:HGNC:29227]",{"v":2.663952,"d":"2.66"},{"v":0.174451,"d":"0.17"},{"v":15.2704885612579,"d":"15.27"},{"v":3.93267431508555,"d":"3.93"},{"v":4.09734287755115e-07,"d":"0.00"},{"v":5.64815581718817e-05,"d":"0.00"},"up","yes"]
[11407,0,"chr1","+",154405223,154466877,"ENST00000344086",9,3217,"MSTRG.1014","IL6R","GO:0008284(positive regulation of cell proliferation);GO:0042531(positive regulation of tyrosine phosphorylation of STAT protein);GO:0032755(positive regulation of interleukin-6 production);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0004896(cytokine receptor activity);GO:0004915(interleukin-6 receptor activity);GO:0019981(interleukin-6 binding);GO:0070102(interleukin-6-mediated signaling pathway);GO:0009986(cell surface);GO:0016323(basolateral plasma membrane);GO:0042803(protein homodimerization activity);GO:0050731(positive regulation of peptidyl-tyrosine phosphorylation);GO:0019899(enzyme binding);GO:0032722(positive regulation of chemokine production);GO:0050829(defense response to Gram-negative bacterium);GO:0045669(positive regulation of osteoblast differentiation);GO:0002548(monocyte chemotaxis);GO:0019221(cytokine-mediated signaling pathway);GO:0097191(extrinsic apoptotic signaling pathway);GO:0016324(apical plasma membrane);GO:0048661(positive regulation of smooth muscle cell proliferation);GO:0006953(acute-phase response);GO:0005138(interleukin-6 receptor binding);GO:0002384(hepatic immune response);GO:0002690(positive regulation of leukocyte chemotaxis);GO:0031018(endocrine pancreas development);GO:0005896(interleukin-6 receptor complex);GO:0004897(ciliary neurotrophic factor receptor activity);GO:0070119(ciliary neurotrophic factor binding);GO:0034097(response to cytokine);GO:0070120(ciliary neurotrophic factor-mediated signaling pathway);GO:0070110(ciliary neurotrophic factor receptor complex)","04630(Jak-STAT signaling pathway);04066(HIF-1 signaling pathway);04151(PI3K-Akt signaling pathway);04060(Cytokine-cytokine receptor interaction);04640(Hematopoietic cell lineage);04659(Th17 cell differentiation);05200(Pathways in cancer);04932(Non-alcoholic fatty liver disease (NAFLD));01521(EGFR tyrosine kinase inhibitor resistance)","K05055","NA","interleukin 6 receptor [Source:HGNC Symbol;Acc:HGNC:6019]",{"v":11.585262,"d":"11.59"},{"v":0.766364,"d":"0.77"},{"v":15.1171793038295,"d":"15.12"},{"v":3.91811706883748,"d":"3.92"},{"v":4.11024074022184E-7,"d":"0.00"},{"v":5.64815581718817e-05,"d":"0.00"},"up","yes"]
[21660,"j","chr10","+",78034251,78040714,"MSTRG.1826.13",6,680,"MSTRG.1826","RPS24","NA","NA","NA","NA","NA",{"v":137.856506,"d":"137.86"},{"v":9.394495,"d":"9.39"},{"v":14.6741795061895,"d":"14.67"},{"v":3.87520793345647,"d":"3.88"},{"v":4.47784270848094E-7,"d":"0.00"},{"v":6.11086562175316e-05,"d":"0.00"},"up","yes"]
[153556,0,"chr5","+",14143702,14510204,"ENST00000344204",57,11100,"ENSG00000038382","TRIO","GO:0005737(cytoplasm);GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0005089(Rho guanyl-nucleotide exchange factor activity);GO:0035023(regulation of Rho protein signal transduction);GO:0043547(positive regulation of GTPase activity);GO:0005515(protein binding);GO:0005085(guanyl-nucleotide exchange factor activity);GO:0005829(cytosol);GO:0051056(regulation of small GTPase mediated signal transduction);GO:0043065(positive regulation of apoptotic process);GO:0019899(enzyme binding);GO:0007185(transmembrane receptor protein tyrosine phosphatase signaling pathway)","NA","NA","NA","trio Rho guanine nucleotide exchange factor [Source:HGNC Symbol;Acc:HGNC:12303]",{"v":2.767757,"d":"2.77"},{"v":0.184859,"d":"0.18"},{"v":14.9722599386559,"d":"14.97"},{"v":3.9042200955899,"d":"3.90"},{"v":4.56988376522711e-07,"d":"0.00"},{"v":6.19375753056946e-05,"d":"0.00"},"up","yes"]
[81816,"j","chr17","-",31303494,31321884,"MSTRG.6660.2",4,3309,"MSTRG.6660","AC134669.2","NA","NA","NA","NA","NA",{"v":9.478382,"d":"9.48"},{"v":0.634319,"d":"0.63"},{"v":14.9426108945184,"d":"14.94"},{"v":3.90136034445216,"d":"3.90"},{"v":4.63003085702583e-07,"d":"0.00"},{"v":6.23258847611069e-05,"d":"0.00"},"up","yes"]
[38520,0,"chr12","-",8533305,8540963,"ENST00000299663",6,2159,"MSTRG.3113","CLEC4E","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0030246(carbohydrate binding);GO:0002376(immune system process);GO:0005886(plasma membrane);GO:0002223(stimulatory C-type lectin receptor signaling pathway);GO:0004872(receptor activity);GO:0002292(T cell differentiation involved in immune response);GO:0006955(immune response);GO:0038094(Fc-gamma receptor signaling pathway);GO:0042742(defense response to bacterium);GO:0045087(innate immune response);GO:0050715(positive regulation of cytokine secretion)","05152(Tuberculosis)","K10059","NA","C-type lectin domain family 4 member E [Source:HGNC Symbol;Acc:HGNC:14555]",{"v":0.534331,"d":"0.53"},{"v":6.226238,"d":"6.23"},{"v":0.0858192378768688,"d":"0.09"},{"v":-3.54255510057545,"d":"-3.54"},{"v":4.82413373089112e-07,"d":"0.00"},{"v":6.44999718019415e-05,"d":"0.00"},"down","yes"]
[24190,0,"chr10","-",124984317,125160513,"ENST00000337195",11,6939,"MSTRG.2035","CTBP2","GO:0005634(nucleus);GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0008152(metabolic process);GO:0016616(oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor);GO:0005515(protein binding);GO:0051287(NAD binding);GO:0030054(cell junction);GO:0045202(synapse);GO:0030154(cell differentiation);GO:0005829(cytosol);GO:0003714(transcription corepressor activity);GO:0016032(viral process);GO:0045892(negative regulation of transcription, DNA-templated);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0019079(viral genome replication);GO:0008285(negative regulation of cell proliferation);GO:0042803(protein homodimerization activity);GO:0050872(white fat cell differentiation);GO:0017053(transcriptional repressor complex);GO:0019901(protein kinase binding);GO:0032403(protein complex binding);GO:0016618(hydroxypyruvate reductase activity);GO:0030267(glyoxylate reductase (NADP) activity);GO:0048386(positive regulation of retinoic acid receptor signaling pathway);GO:0003682(chromatin binding);GO:0003713(transcription coactivator activity);GO:0042974(retinoic acid receptor binding);GO:0035563(positive regulation of chromatin binding);GO:1990830(cellular response to leukemia inhibitory factor);GO:0097470(ribbon synapse)","04310(Wnt signaling pathway);04330(Notch signaling pathway);05200(Pathways in cancer);05220(Chronic myeloid leukemia)","K04496","NA","C-terminal binding protein 2 [Source:HGNC Symbol;Acc:HGNC:2495]",{"v":0.24492,"d":"0.24"},{"v":2.765269,"d":"2.77"},{"v":0.0885700450842215,"d":"0.09"},{"v":-3.49703733654231,"d":"-3.50"},{"v":5.13988547848657e-07,"d":"0.00"},{"v":6.82604388243573e-05,"d":"0.00"},"down","yes"]
[165200,0,"chr6","+",33272132,33276510,"ENST00000490191",5,996,"MSTRG.12945","RPS18","GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0006412(translation);GO:0005829(cytosol);GO:0030529(intracellular ribonucleoprotein complex);GO:0005622(intracellular);GO:0003735(structural constituent of ribosome);GO:0005840(ribosome);GO:0022627(cytosolic small ribosomal subunit);GO:0005925(focal adhesion);GO:0005515(protein binding);GO:0005654(nucleoplasm);GO:0070062(extracellular exosome);GO:0031012(extracellular matrix);GO:0019843(rRNA binding);GO:0042254(ribosome biogenesis);GO:0006413(translational initiation);GO:0006364(rRNA processing);GO:0000184(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay);GO:0019083(viral transcription);GO:0006614(SRP-dependent cotranslational protein targeting to membrane);GO:0015935(small ribosomal subunit);GO:0005581(collagen trimer)","03010(Ribosome)","NA","NA","ribosomal protein S18 [Source:HGNC Symbol;Acc:HGNC:10401]",{"v":102.81781,"d":"102.82"},{"v":7.136319,"d":"7.14"},{"v":14.4076813270259,"d":"14.41"},{"v":3.84876627167979,"d":"3.85"},{"v":5.2252627939508E-7,"d":"0.00"},{"v":6.8931666777799e-05,"d":"0.00"},"up","yes"]
[3387,0,"chr1","+",28329038,28335967,"ENST00000373842",3,1833,"MSTRG.325","MED18","GO:0005634(nucleus);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0001104(RNA polymerase II transcription cofactor activity);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0016592(mediator complex);GO:0005515(protein binding);GO:0070847(core mediator complex);GO:0006369(termination of RNA polymerase II transcription);GO:0061630(ubiquitin protein ligase activity);GO:0016567(protein ubiquitination);GO:0000151(ubiquitin ligase complex)","NA","NA","NA","mediator complex subunit 18 [Source:HGNC Symbol;Acc:HGNC:25944]",{"v":0.52204,"d":"0.52"},{"v":6.002071,"d":"6.00"},{"v":0.0869766452279555,"d":"0.09"},{"v":-3.52322812602138,"d":"-3.52"},{"v":5.49721184429122e-07,"d":"0.00"},{"v":7.20389589237315e-05,"d":"0.00"},"down","yes"]
[56962,"j","chr14","+",75278817,75283215,"MSTRG.4548.2",3,3531,"MSTRG.4548","FOS","NA","NA","NA","NA","NA",{"v":13.661026,"d":"13.66"},{"v":0.945406,"d":"0.95"},{"v":14.4499040623817,"d":"14.45"},{"v":3.85298800912296,"d":"3.85"},{"v":5.5993440854816e-07,"d":"0.00"},{"v":7.28946189233618e-05,"d":"0.00"},"up","yes"]
[122763,0,"chr20","+",31514428,31569567,"ENST00000335574",13,1809,"MSTRG.9638","HM13","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005783(endoplasmic reticulum);GO:0016787(hydrolase activity);GO:0005789(endoplasmic reticulum membrane);GO:0042803(protein homodimerization activity);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0008233(peptidase activity);GO:0006508(proteolysis);GO:0004190(aspartic-type endopeptidase activity);GO:0031625(ubiquitin protein ligase binding);GO:0005765(lysosomal membrane);GO:0009986(cell surface);GO:0005791(rough endoplasmic reticulum);GO:0033619(membrane protein proteolysis);GO:0042500(aspartic endopeptidase activity, intramembrane cleaving);GO:0036513(Derlin-1 retrotranslocation complex);GO:0030660(Golgi-associated vesicle membrane);GO:0071458(integral component of cytoplasmic side of endoplasmic reticulum membrane);GO:0071556(integral component of lumenal side of endoplasmic reticulum membrane);GO:0051289(protein homotetramerization);GO:1904211(membrane protein proteolysis involved in retrograde protein transport, ER to cytosol)","NA","NA","NA","histocompatibility minor 13 [Source:HGNC Symbol;Acc:HGNC:16435]",{"v":0.627716,"d":"0.63"},{"v":7.202618,"d":"7.20"},{"v":0.0871510886735906,"d":"0.09"},{"v":-3.52033750345956,"d":"-3.52"},{"v":5.75940637996048e-07,"d":"0.00"},{"v":7.44883225141556e-05,"d":"0.00"},"down","yes"]
[61694,0,"chr15","+",43185439,43195195,"ENST00000565296",11,1831,"MSTRG.5021","CCNDBP1","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005654(nucleoplasm);GO:0005515(protein binding);GO:0007049(cell cycle);GO:0051726(regulation of cell cycle)","NA","NA","NA","cyclin D1 binding protein 1 [Source:HGNC Symbol;Acc:HGNC:1587]",{"v":11.175229,"d":"11.18"},{"v":0.752808,"d":"0.75"},{"v":14.8447266766559,"d":"14.84"},{"v":3.89187862533802,"d":"3.89"},{"v":6.00444741190704e-07,"d":"0.00"},{"v":7.71532502511795e-05,"d":"0.00"},"up","yes"]
[143959,"j","chr3","-",187722320,187743672,"MSTRG.11421.4",9,8216,"MSTRG.11421","BCL6","NA","NA","NA","NA","NA",{"v":8.404726,"d":"8.40"},{"v":0.591114,"d":"0.59"},{"v":14.2184519398965,"d":"14.22"},{"v":3.82969249231927,"d":"3.83"},{"v":6.07612949999103e-07,"d":"0.00"},{"v":7.75706132553693e-05,"d":"0.00"},"up","yes"]
[21410,0,"chr10","+",74826625,75032622,"ENST00000287239",18,8287,"ENSG00000156650","KAT6B","GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0016740(transferase activity);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0016569(covalent chromatin modification);GO:0003677(DNA binding);GO:0016746(transferase activity, transferring acyl groups);GO:0006334(nucleosome assembly);GO:0000786(nucleosome);GO:0016747(transferase activity, transferring acyl groups other than amino-acyl groups);GO:0004402(histone acetyltransferase activity);GO:0045893(positive regulation of transcription, DNA-templated);GO:0005515(protein binding);GO:0005654(nucleoplasm);GO:0008134(transcription factor binding);GO:0045892(negative regulation of transcription, DNA-templated);GO:0043966(histone H3 acetylation);GO:0070776(MOZ/MORF histone acetyltransferase complex);GO:0016407(acetyltransferase activity);GO:0016573(histone acetylation);GO:0032403(protein complex binding);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:1990830(cellular response to leukemia inhibitory factor)","NA","NA","NA","lysine acetyltransferase 6B [Source:HGNC Symbol;Acc:HGNC:17582]",{"v":2.678419,"d":"2.68"},{"v":0.184296,"d":"0.18"},{"v":14.5332454312628,"d":"14.53"},{"v":3.86128500327863,"d":"3.86"},{"v":6.31368017724922e-07,"d":"0.00"},{"v":7.9844792067007e-05,"d":"0.00"},"up","yes"]
[71730,0,"chr16","+",30064185,30070257,"ENST00000569545",11,1359,"MSTRG.5821","ALDOA","GO:0070062(extracellular exosome);GO:0008360(regulation of cell shape);GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005829(cytosol);GO:0003824(catalytic activity);GO:0004332(fructose-bisphosphate aldolase activity);GO:0016829(lyase activity);GO:0006096(glycolytic process);GO:0005515(protein binding);GO:0005615(extracellular space);GO:0005576(extracellular region);GO:0045296(cadherin binding);GO:0031430(M band);GO:0031674(I band);GO:0043312(neutrophil degranulation);GO:0015629(actin cytoskeleton);GO:0002576(platelet degranulation);GO:0034774(secretory granule lumen);GO:1904813(ficolin-1-rich granule lumen);GO:0031093(platelet alpha granule lumen);GO:1904724(tertiary granule lumen);GO:0051289(protein homotetramerization);GO:0006094(gluconeogenesis);GO:0061621(canonical glycolysis);GO:0042802(identical protein binding);GO:0003779(actin binding);GO:0006754(ATP biosynthetic process);GO:0046716(muscle cell cellular homeostasis);GO:0008092(cytoskeletal protein binding);GO:0015631(tubulin binding);GO:0070061(fructose binding);GO:0006000(fructose metabolic process);GO:0006941(striated muscle contraction);GO:0007015(actin filament organization);GO:0030388(fructose 1,6-bisphosphate metabolic process);GO:0016021(integral component of membrane)","00010(Glycolysis / Gluconeogenesis);00030(Pentose phosphate pathway);00051(Fructose and mannose metabolism);04066(HIF-1 signaling pathway)","NA","NA","aldolase, fructose-bisphosphate A [Source:HGNC Symbol;Acc:HGNC:414]",{"v":1.294845,"d":"1.29"},{"v":14.304435,"d":"14.30"},{"v":0.0905205273749016,"d":"0.09"},{"v":-3.46561119996732,"d":"-3.47"},{"v":6.38623785531752e-07,"d":"0.00"},{"v":7.9844792067007e-05,"d":"0.00"},"down","yes"]
[46116,0,"chr12","-",106237877,106247988,"ENST00000378026",2,3093,"MSTRG.3671","CKAP4","GO:0003723(RNA binding);GO:0005737(cytoplasm);GO:0016607(nuclear speck);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005829(cytosol);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005886(plasma membrane);GO:0005856(cytoskeleton);GO:0048471(perinuclear region of cytoplasm);GO:0000932(P-body);GO:0070062(extracellular exosome);GO:0044267(cellular protein metabolic process);GO:0043687(post-translational protein modification);GO:0031012(extracellular matrix);GO:0043312(neutrophil degranulation);GO:0035579(specific granule membrane);GO:0005788(endoplasmic reticulum lumen);GO:0035577(azurophil granule membrane);GO:0005811(lipid particle);GO:0005791(rough endoplasmic reticulum);GO:0042599(lamellar body)","04141(Protein processing in endoplasmic reticulum)","K13999","NA","cytoskeleton associated protein 4 [Source:HGNC Symbol;Acc:HGNC:16991]",{"v":1.176048,"d":"1.18"},{"v":12.66215,"d":"12.66"},{"v":0.0928790134376863,"d":"0.09"},{"v":-3.42850354181884,"d":"-3.43"},{"v":6.39167275084767e-07,"d":"0.00"},{"v":7.9844792067007e-05,"d":"0.00"},"down","yes"]
[158382,0,"chr5","+",134115625,134148229,"ENST00000395023",9,2815,"MSTRG.12319","TCF7","GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0008013(beta-catenin binding);GO:0060070(canonical Wnt signaling pathway);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0016604(nuclear body);GO:0016055(Wnt signaling pathway);GO:0005667(transcription factor complex);GO:0033153(T cell receptor V(D)J recombination);GO:0006955(immune response);GO:0044212(transcription regulatory region DNA binding);GO:1904837(beta-catenin-TCF complex assembly);GO:0043565(sequence-specific DNA binding);GO:0071353(cellular response to interleukin-4);GO:0001047(core promoter binding);GO:0001227(transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0021915(neural tube development);GO:0030538(embryonic genitalia morphogenesis);GO:0042127(regulation of cell proliferation);GO:0044336(canonical Wnt signaling pathway involved in negative regulation of apoptotic process);GO:0046632(alpha-beta T cell differentiation);GO:0048557(embryonic digestive tract morphogenesis);GO:0048619(embryonic hindgut morphogenesis);GO:0005719(nuclear euchromatin)","04310(Wnt signaling pathway);04390(Hippo signaling pathway);04520(Adherens junction);04916(Melanogenesis);05200(Pathways in cancer);05210(Colorectal cancer);05225(Hepatocellular carcinoma);05226(Gastric cancer);05216(Thyroid cancer);05221(Acute myeloid leukemia);05217(Basal cell carcinoma);05215(Prostate cancer);05213(Endometrial cancer);05224(Breast cancer);05412(Arrhythmogenic right ventricular cardiomyopathy (ARVC));05165(Human papillomavirus infection)","K02620","NA","transcription factor 7 [Source:HGNC Symbol;Acc:HGNC:11639]",{"v":5.007617,"d":"5.01"},{"v":0.332265,"d":"0.33"},{"v":15.0711540487262,"d":"15.07"},{"v":3.91371798804258,"d":"3.91"},{"v":6.41566703995053e-07,"d":"0.00"},{"v":7.9844792067007e-05,"d":"0.00"},"up","yes"]
[179301,0,"chr7","-",140453047,140479336,"ENST00000475010",7,3467,"MSTRG.14012","MKRN1","GO:0003723(RNA binding);GO:0046872(metal ion binding);GO:0016740(transferase activity);GO:0016567(protein ubiquitination);GO:0005515(protein binding);GO:0061630(ubiquitin protein ligase activity);GO:0005575(cellular_component);GO:0005829(cytosol);GO:0004842(ubiquitin-protein transferase activity);GO:0000209(protein polyubiquitination)","NA","NA","NA","makorin ring finger protein 1 [Source:HGNC Symbol;Acc:HGNC:7112]",{"v":14.361131,"d":"14.36"},{"v":1.010422,"d":"1.01"},{"v":14.2130030818806,"d":"14.21"},{"v":3.82913951038231,"d":"3.83"},{"v":6.46332862845084e-07,"d":"0.00"},{"v":7.99352168123657e-05,"d":"0.00"},"up","yes"]
[169641,0,"chr6","+",138404219,138422197,"ENST00000607197",4,10014,"MSTRG.13303","HEBP2","GO:0005737(cytoplasm);GO:0005739(mitochondrion);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0070062(extracellular exosome);GO:0043312(neutrophil degranulation);GO:0035578(azurophil granule lumen);GO:0010917(negative regulation of mitochondrial membrane potential);GO:0010940(positive regulation of necrotic cell death);GO:0035794(positive regulation of mitochondrial membrane permeability)","NA","NA","NA","heme binding protein 2 [Source:HGNC Symbol;Acc:HGNC:15716]",{"v":0.333995,"d":"0.33"},{"v":3.591386,"d":"3.59"},{"v":0.0929989146251614,"d":"0.09"},{"v":-3.42664231090927,"d":"-3.43"},{"v":6.58482732988126e-07,"d":"0.00"},{"v":8.09320268345903e-05,"d":"0.00"},"down","yes"]
[90317,0,"chr18","+",3449704,3458411,"ENST00000343820",3,2076,"ENSG00000177426","TGIF1","GO:0005634(nucleus);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0005654(nucleoplasm);GO:0006351(transcription, DNA-templated);GO:0005515(protein binding);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:0001078(transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0007275(multicellular organism development);GO:0003714(transcription corepressor activity);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0070410(co-SMAD binding);GO:0010629(negative regulation of gene expression);GO:0042493(response to drug);GO:0071363(cellular response to growth factor stimulus)","04350(TGF-beta signaling pathway)","K19383","NA","TGFB induced factor homeobox 1 [Source:HGNC Symbol;Acc:HGNC:11776]",{"v":0.456372,"d":"0.46"},{"v":5.115823,"d":"5.12"},{"v":0.0892079338945073,"d":"0.09"},{"v":-3.48668416481692,"d":"-3.49"},{"v":6.64228284589404e-07,"d":"0.00"},{"v":8.11342549102168e-05,"d":"0.00"},"down","yes"]
[170561,"j","chr6","-",159669057,159693587,"MSTRG.13403.1",6,14381,"MSTRG.13403","SOD2","NA","NA","NA","NA","NA",{"v":9.692585,"d":"9.69"},{"v":0.696087,"d":"0.70"},{"v":13.9243873251476,"d":"13.92"},{"v":3.79954194507982,"d":"3.80"},{"v":6.83418946215107e-07,"d":"0.00"},{"v":8.29662215196597e-05,"d":"0.00"},"up","yes"]
[30127,0,"chr11","-",61964747,61967586,"ENST00000534719",3,788,"MSTRG.2449","FTH1","GO:0005623(cell);GO:0008199(ferric iron binding);GO:0006826(iron ion transport);GO:0006879(cellular iron ion homeostasis);GO:0046872(metal ion binding);GO:0005634(nucleus);GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0005515(protein binding);GO:0006955(immune response);GO:0005576(extracellular region);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0008285(negative regulation of cell proliferation);GO:0043312(neutrophil degranulation);GO:1904813(ficolin-1-rich granule lumen);GO:1904724(tertiary granule lumen);GO:0004322(ferroxidase activity);GO:0048147(negative regulation of fibroblast proliferation);GO:0005506(iron ion binding);GO:0008043(intracellular ferritin complex);GO:0044754(autolysosome);GO:0006880(intracellular sequestering of iron ion);GO:0016020(membrane);GO:0016021(integral component of membrane)","04216(Ferroptosis);04217(Necroptosis);04978(Mineral absorption)","NA","NA","ferritin heavy chain 1 [Source:HGNC Symbol;Acc:HGNC:3976]",{"v":10.317324,"d":"10.32"},{"v":108.484482,"d":"108.48"},{"v":0.095104145863,"d":"0.10"},{"v":-3.39434795609562,"d":"-3.39"},{"v":7.17485449318635e-07,"d":"0.00"},{"v":8.65707443360802e-05,"d":"0.00"},"down","yes"]
[41371,0,"chr12","-",49791146,49828425,"ENST00000335999",13,4900,"ENSG00000167566","NCKAP5L","GO:0005737(cytoplasm);GO:0005856(cytoskeleton);GO:0005874(microtubule);GO:0005813(centrosome);GO:0005815(microtubule organizing center);GO:0005515(protein binding);GO:0001578(microtubule bundle formation);GO:0035371(microtubule plus-end);GO:0007019(microtubule depolymerization)","NA","NA","NA","NCK associated protein 5 like [Source:HGNC Symbol;Acc:HGNC:29321]",{"v":2.693573,"d":"2.69"},{"v":0.182334,"d":"0.18"},{"v":14.7727412331216,"d":"14.77"},{"v":3.88486565264101,"d":"3.88"},{"v":7.43046937124687e-07,"d":"0.00"},{"v":8.9111592677717e-05,"d":"0.00"},"up","yes"]
[163276,0,"chr6","-",24839359,25042018,"ENST00000510784",14,3381,"MSTRG.12716","RIPOR2","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0007155(cell adhesion);GO:0007605(sensory perception of sound);GO:0048741(skeletal muscle fiber development);GO:0005886(plasma membrane);GO:0005856(cytoskeleton);GO:0042995(cell projection);GO:0005515(protein binding);GO:0007275(multicellular organism development);GO:0030154(cell differentiation);GO:0006935(chemotaxis);GO:2000114(regulation of establishment of cell polarity);GO:0030175(filopodium);GO:0032420(stereocilium);GO:0007517(muscle organ development);GO:0060171(stereocilium membrane);GO:0016324(apical plasma membrane);GO:0051491(positive regulation of filopodium assembly);GO:0007162(negative regulation of cell adhesion);GO:0009968(negative regulation of signal transduction);GO:1901741(positive regulation of myoblast fusion);GO:0071889(14-3-3 protein binding);GO:2000405(negative regulation of T cell migration);GO:0090023(positive regulation of neutrophil chemotaxis);GO:0045663(positive regulation of myoblast differentiation);GO:1990869(cellular response to chemokine);GO:0035024(negative regulation of Rho protein signal transduction);GO:1903904(negative regulation of establishment of T cell polarity);GO:1905872(negative regulation of protein localization to cell leading edge);GO:2000391(positive regulation of neutrophil extravasation);GO:2001107(negative regulation of Rho guanyl-nucleotide exchange factor activity)","NA","NA","NA","RHO family interacting cell polarization regulator 2 [Source:HGNC Symbol;Acc:HGNC:13872]",{"v":22.65519,"d":"22.66"},{"v":1.636174,"d":"1.64"},{"v":13.8464429822256,"d":"13.85"},{"v":3.79144350430348,"d":"3.79"},{"v":7.51133041141365e-07,"d":"0.00"},{"v":8.95386784223213E-5,"d":"0.00"},"up","yes"]
[175313,0,"chr7","-",76326794,76359031,"ENST00000307630",2,3750,"MSTRG.13739","YWHAG","GO:0005739(mitochondrion);GO:0003723(RNA binding);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0019904(protein domain specific binding);GO:0005515(protein binding);GO:0071901(negative regulation of protein serine/threonine kinase activity);GO:0005925(focal adhesion);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0061024(membrane organization);GO:0000086(G2/M transition of mitotic cell cycle);GO:0010389(regulation of G2/M transition of mitotic cell cycle);GO:0097711(ciliary basal body docking);GO:0005159(insulin-like growth factor receptor binding);GO:0009966(regulation of signal transduction);GO:0048167(regulation of synaptic plasticity);GO:0006469(negative regulation of protein kinase activity);GO:1900740(positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway);GO:0030659(cytoplasmic vesicle membrane);GO:0005080(protein kinase C binding);GO:0008426(protein kinase C inhibitor activity);GO:0030971(receptor tyrosine kinase binding);GO:0006605(protein targeting);GO:0032869(cellular response to insulin stimulus);GO:0045664(regulation of neuron differentiation);GO:0031982(vesicle);GO:0043209(myelin sheath)","04390(Hippo signaling pathway);04151(PI3K-Akt signaling pathway);04110(Cell cycle);04114(Oocyte meiosis);05203(Viral carcinogenesis);05169(Epstein-Barr virus infection)","K16198","NA","tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein gamma [Source:HGNC Symbol;Acc:HGNC:12852]",{"v":1.052171,"d":"1.05"},{"v":11.063588,"d":"11.06"},{"v":0.0951021495015903,"d":"0.10"},{"v":-3.39437824048448,"d":"-3.39"},{"v":7.89932612690098e-07,"d":"0.00"},{"v":9.35999194006686e-05,"d":"0.00"},"down","yes"]
[11723,0,"chr1","+",155308794,155320609,"ENST00000447866",10,1256,"MSTRG.1045","FDPS","GO:0003723(RNA binding);GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0016740(transferase activity);GO:0006629(lipid metabolic process);GO:0006694(steroid biosynthetic process);GO:0008202(steroid metabolic process);GO:0008299(isoprenoid biosynthetic process);GO:0016126(sterol biosynthetic process);GO:0008203(cholesterol metabolic process);GO:0006695(cholesterol biosynthetic process);GO:0016032(viral process);GO:0045540(regulation of cholesterol biosynthetic process);GO:0004161(dimethylallyltranstransferase activity);GO:0004337(geranyltranstransferase activity);GO:0033384(geranyl diphosphate biosynthetic process);GO:0045337(farnesyl diphosphate biosynthetic process);GO:0005739(mitochondrion);GO:0016020(membrane);GO:0016021(integral component of membrane)","00900(Terpenoid backbone biosynthesis);05166(HTLV-I infection);05164(Influenza A)","K00787","EC:2.5.1.1;EC:2.5.1.10","farnesyl diphosphate synthase [Source:HGNC Symbol;Acc:HGNC:3631]",{"v":0.597468,"d":"0.60"},{"v":6.682819,"d":"6.68"},{"v":0.0894035885155651,"d":"0.09"},{"v":-3.48352344975643,"d":"-3.48"},{"v":8.0468111282104e-07,"d":"0.00"},{"v":9.4444654737993e-05,"d":"0.00"},"down","yes"]
[49263,0,"chr13","+",27251583,27256568,"ENST00000319826",6,806,"MSTRG.3921","RPL21","GO:0003723(RNA binding);GO:0016020(membrane);GO:0006412(translation);GO:0030529(intracellular ribonucleoprotein complex);GO:0005622(intracellular);GO:0003735(structural constituent of ribosome);GO:0005840(ribosome);GO:0005829(cytosol);GO:0005515(protein binding);GO:0006413(translational initiation);GO:0006364(rRNA processing);GO:0000184(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay);GO:0019083(viral transcription);GO:0006614(SRP-dependent cotranslational protein targeting to membrane);GO:0022625(cytosolic large ribosomal subunit)","03010(Ribosome)","NA","NA","ribosomal protein L21 [Source:HGNC Symbol;Acc:HGNC:10313]",{"v":12.007007,"d":"12.01"},{"v":124.201012,"d":"124.20"},{"v":0.096673986843199,"d":"0.10"},{"v":-3.3707284500317,"d":"-3.37"},{"v":8.06607370665091e-07,"d":"0.00"},{"v":9.4444654737993e-05,"d":"0.00"},"down","yes"]
[89493,0,"chr17","-",81867721,81871406,"ENST00000269321",6,1906,"MSTRG.7335","ARHGDIA","GO:0005737(cytoplasm);GO:0050790(regulation of catalytic activity);GO:0043547(positive regulation of GTPase activity);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0005096(GTPase activator activity);GO:0005094(Rho GDP-dissociation inhibitor activity);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0051056(regulation of small GTPase mediated signal transduction);GO:0043066(negative regulation of apoptotic process);GO:0071526(semaphorin-plexin signaling pathway);GO:2000249(regulation of actin cytoskeleton reorganization);GO:0006928(movement of cell or subcellular component);GO:0050772(positive regulation of axonogenesis);GO:0035023(regulation of Rho protein signal transduction);GO:0050771(negative regulation of axonogenesis);GO:0007162(negative regulation of cell adhesion);GO:0005504(fatty acid binding);GO:0017048(Rho GTPase binding);GO:0019901(protein kinase binding);GO:0051879(Hsp90 protein binding);GO:0007266(Rho protein signal transduction);GO:0008360(regulation of cell shape);GO:0030336(negative regulation of cell migration);GO:0032880(regulation of protein localization);GO:0071260(cellular response to mechanical stimulus);GO:0071407(cellular response to organic cyclic compound);GO:0071461(cellular response to redox state);GO:0001772(immunological synapse);GO:0005615(extracellular space);GO:0005634(nucleus);GO:0016020(membrane)","04962(Vasopressin-regulated water reabsorption);04722(Neurotrophin signaling pathway)","K12462","NA","Rho GDP dissociation inhibitor alpha [Source:HGNC Symbol;Acc:HGNC:678]",{"v":57.807644,"d":"57.81"},{"v":4.22961,"d":"4.23"},{"v":13.6673698047811,"d":"13.67"},{"v":3.77266372739275,"d":"3.77"},{"v":8.11608412803459e-07,"d":"0.00"},{"v":9.44712192503226e-05,"d":"0.00"},"up","yes"]
[155623,0,"chr5","-",70970050,71020710,"ENST00000508426",14,4153,"MSTRG.12100","NAIP","GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0016567(protein ubiquitination);GO:0006915(apoptotic process);GO:0002376(immune system process);GO:0045087(innate immune response);GO:0006954(inflammatory response);GO:0005634(nucleus);GO:0004869(cysteine-type endopeptidase inhibitor activity);GO:0030414(peptidase inhibitor activity);GO:0010466(negative regulation of peptidase activity);GO:0004842(ubiquitin-protein transferase activity);GO:0005515(protein binding);GO:0070062(extracellular exosome);GO:0016323(basolateral plasma membrane);GO:0007399(nervous system development);GO:0043524(negative regulation of neuron apoptotic process);GO:0043066(negative regulation of apoptotic process);GO:0043154(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process);GO:1990001(inhibition of cysteine-type endopeptidase activity involved in apoptotic process);GO:0043027(cysteine-type endopeptidase inhibitor activity involved in apoptotic process);GO:0043200(response to amino acid);GO:0048678(response to axon injury);GO:0090263(positive regulation of canonical Wnt signaling pathway);GO:0043005(neuron projection);GO:0043025(neuronal cell body);GO:0043204(perikaryon)","04621(NOD-like receptor signaling pathway);05134(Legionellosis)","NA","NA","NLR family apoptosis inhibitory protein [Source:HGNC Symbol;Acc:HGNC:7634]",{"v":3.052343,"d":"3.05"},{"v":0.207383,"d":"0.21"},{"v":14.7183857886133,"d":"14.72"},{"v":3.87954755008242,"d":"3.88"},{"v":8.47101481176255e-07,"d":"0.00"},{"v":9.80259889445365e-05,"d":"0.00"},"up","yes"]
[56571,0,"chr14","-",73275107,73458617,"ENST00000554546",11,3607,"MSTRG.4515","NUMB","GO:0016020(membrane);GO:0005515(protein binding);GO:0007275(multicellular organism development);GO:0007399(nervous system development);GO:0005925(focal adhesion);GO:0005886(plasma membrane);GO:0045296(cadherin binding);GO:0030335(positive regulation of cell migration);GO:0030136(clathrin-coated vesicle);GO:0050769(positive regulation of neurogenesis);GO:1903077(negative regulation of protein localization to plasma membrane);GO:0021670(lateral ventricle development);GO:0021849(neuroblast division in subventricular zone);GO:0008013(beta-catenin binding);GO:0045294(alpha-catenin binding);GO:0007405(neuroblast proliferation);GO:0007409(axonogenesis);GO:0030862(positive regulation of polarized epithelial cell differentiation);GO:0030900(forebrain development);GO:0034332(adherens junction organization);GO:0045746(negative regulation of Notch signaling pathway);GO:0060487(lung epithelial cell differentiation);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005769(early endosome);GO:0016323(basolateral plasma membrane);GO:0019897(extrinsic component of plasma membrane);GO:0031410(cytoplasmic vesicle);GO:0045177(apical part of cell)","04330(Notch signaling pathway)","K06057","NA","NUMB, endocytic adaptor protein [Source:HGNC Symbol;Acc:HGNC:8060]",{"v":1.002912,"d":"1.00"},{"v":10.435739,"d":"10.44"},{"v":0.0961035917053886,"d":"0.10"},{"v":-3.37926583953822,"d":"-3.38"},{"v":8.69167726600682e-07,"d":"0.00"},{"v":9.95609164971231e-05,"d":"0.00"},"down","yes"]
[46832,0,"chr12","+",112125545,112153603,"ENST00000257604",12,3178,"MSTRG.3733","TRAFD1","GO:0046872(metal ion binding);GO:0005515(protein binding);GO:0045824(negative regulation of innate immune response);GO:0034097(response to cytokine)","NA","NA","NA","TRAF-type zinc finger domain containing 1 [Source:HGNC Symbol;Acc:HGNC:24808]",{"v":5.196695,"d":"5.20"},{"v":0.362217,"d":"0.36"},{"v":14.346910829696,"d":"14.35"},{"v":3.84266822478803,"d":"3.84"},{"v":8.70428469476567e-07,"d":"0.00"},{"v":9.95609164971231e-05,"d":"0.00"},"up","yes"]
[178980,0,"chr7","+",135148072,135166215,"ENST00000275767",2,1997,"MSTRG.13990","TMEM140","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005515(protein binding)","NA","NA","NA","transmembrane protein 140 [Source:HGNC Symbol;Acc:HGNC:21870]",{"v":3.615404,"d":"3.62"},{"v":36.80558,"d":"36.81"},{"v":0.0982297792889013,"d":"0.10"},{"v":-3.34769573224569,"d":"-3.35"},{"v":9.5179721479032e-07,"d":"0.00"},{"v":1.08242317737189E-4,"d":"0.00"},"down","yes"]
[124508,0,"chr20","-",49245897,49278065,"ENST00000371752",14,7212,"MSTRG.9811","ZNFX1","GO:0005634(nucleus);GO:0003723(RNA binding);GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0006355(regulation of transcription, DNA-templated);GO:0003700(transcription factor activity, sequence-specific DNA binding)","NA","NA","NA","zinc finger NFX1-type containing 1 [Source:HGNC Symbol;Acc:HGNC:29271]",{"v":0.528524,"d":"0.53"},{"v":5.40872,"d":"5.41"},{"v":0.097717019923383,"d":"0.10"},{"v":-3.35524632337908,"d":"-3.36"},{"v":9.6066719527676e-07,"d":"0.00"},{"v":1.08626756915066E-4,"d":"0.00"},"down","yes"]
[55809,0,"chr14","+",64209120,64226430,"ENST00000554805",14,3481,"ENSG00000054654","SYNE2","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0031965(nuclear membrane);GO:0051015(actin filament binding);GO:0003779(actin binding);GO:0005739(mitochondrion);GO:0045111(intermediate filament cytoskeleton);GO:0005886(plasma membrane);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0016235(aggresome);GO:0034993(LINC complex);GO:0030054(cell junction);GO:0005654(nucleoplasm);GO:0005925(focal adhesion);GO:0090286(cytoskeletal anchoring at nuclear membrane);GO:0005635(nuclear envelope);GO:0070062(extracellular exosome);GO:0016529(sarcoplasmic reticulum);GO:0030335(positive regulation of cell migration);GO:0033017(sarcoplasmic reticulum membrane);GO:0030018(Z disc);GO:0031527(filopodium membrane);GO:0031258(lamellipodium membrane);GO:0051642(centrosome localization);GO:0005640(nuclear outer membrane);GO:0031981(nuclear lumen);GO:0007097(nuclear migration);GO:0031022(nuclear migration along microfilament);GO:0006998(nuclear envelope organization);GO:0007163(establishment or maintenance of cell polarity);GO:0010761(fibroblast migration);GO:0021817(nucleokinesis involved in cell motility in cerebral cortex radial glia guided migration);GO:0034504(protein localization to nucleus);GO:1902017(regulation of cilium assembly);GO:0030016(myofibril)","NA","NA","NA","spectrin repeat containing nuclear envelope protein 2 [Source:HGNC Symbol;Acc:HGNC:17084]",{"v":0.211724,"d":"0.21"},{"v":2.3089,"d":"2.31"},{"v":0.091699077482784,"d":"0.09"},{"v":-3.4469489697789,"d":"-3.45"},{"v":1.01168780127913e-06,"d":"0.00"},{"v":0.000113745898930179,"d":"0.00"},"down","yes"]
[2932,0,"chr1","+",25800176,25818224,"ENST00000361547",13,4334,"MSTRG.273","SELENON","GO:0016020(membrane);GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0005509(calcium ion binding);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005515(protein binding);GO:0003674(molecular_function);GO:0008150(biological_process);GO:0048741(skeletal muscle fiber development);GO:0055074(calcium ion homeostasis);GO:0060314(regulation of ryanodine-sensitive calcium-release channel activity);GO:1902884(positive regulation of response to oxidative stress)","NA","NA","NA","selenoprotein N [Source:HGNC Symbol;Acc:HGNC:15999]",{"v":2.740336,"d":"2.74"},{"v":0.193639,"d":"0.19"},{"v":14.1517772762718,"d":"14.15"},{"v":3.8229113427608,"d":"3.82"},{"v":1.04841052027202E-6,"d":"0.00"},{"v":1.17208742232445E-4,"d":"0.00"},"up","yes"]
[194474,"j","chr9","+",133348252,133351431,"MSTRG.15075.4",8,1429,"MSTRG.15075","RPL7A","NA","NA","NA","NA","NA",{"v":9.335002,"d":"9.34"},{"v":92.369438,"d":"92.37"},{"v":0.101061587058698,"d":"0.10"},{"v":-3.30669335373599,"d":"-3.31"},{"v":1.1465721894606E-6,"d":"0.00"},{"v":1.27462755533968E-4,"d":"0.00"},"down","yes"]
[80009,"j","chr17","+",17136338,17185616,"MSTRG.6479.8",18,3570,"MSTRG.6479","MPRIP","NA","NA","NA","NA","NA",{"v":0.288674,"d":"0.29"},{"v":3.053463,"d":"3.05"},{"v":0.0945398716146225,"d":"0.09"},{"v":-3.40293328426024,"d":"-3.40"},{"v":1.16473848974189e-06,"d":"0.00"},{"v":0.000128758911927445,"d":"0.00"},"down","yes"]
[160243,0,"chr5","+",151771910,151812785,"ENST00000394123",12,10240,"MSTRG.12477","G3BP1","GO:0003723(RNA binding);GO:0006810(transport);GO:0005622(intracellular);GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0005829(cytosol);GO:0016787(hydrolase activity);GO:0004386(helicase activity);GO:0032508(DNA duplex unwinding);GO:0003677(DNA binding);GO:0005886(plasma membrane);GO:0090305(nucleic acid phosphodiester bond hydrolysis);GO:0005515(protein binding);GO:0004519(endonuclease activity);GO:0004518(nuclease activity);GO:0005925(focal adhesion);GO:0003729(mRNA binding);GO:0004004(ATP-dependent RNA helicase activity);GO:0004003(ATP-dependent DNA helicase activity);GO:0007265(Ras protein signal transduction);GO:0090090(negative regulation of canonical Wnt signaling pathway);GO:0010494(cytoplasmic stress granule);GO:0030529(intracellular ribonucleoprotein complex)","NA","NA","NA","G3BP stress granule assembly factor 1 [Source:HGNC Symbol;Acc:HGNC:30292]",{"v":0.417271,"d":"0.42"},{"v":4.167576,"d":"4.17"},{"v":0.100123189115207,"d":"0.10"},{"v":-3.32015194541828,"d":"-3.32"},{"v":1.18776129301759e-06,"d":"0.00"},{"v":1.30574558145734E-4,"d":"0.00"},"down","yes"]
[27936,"j","chr11","-",33858576,33891923,"MSTRG.2316.2",4,1586,"MSTRG.2316","LMO2","NA","NA","NA","NA","NA",{"v":1.132327,"d":"1.13"},{"v":11.533227,"d":"11.53"},{"v":0.0981795467998679,"d":"0.10"},{"v":-3.34843368258484,"d":"-3.35"},{"v":1.2186816477821e-06,"d":"0.00"},{"v":1.33233549427139E-4,"d":"0.00"},"down","yes"]
[192236,0,"chr9","+",99105089,99154192,"ENST00000374994",9,6516,"MSTRG.14874","TGFBR1","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0043231(intracellular membrane-bounded organelle);GO:0005524(ATP binding);GO:0005886(plasma membrane);GO:0004702(signal transducer, downstream of receptor, with serine/threonine kinase activity);GO:0023014(signal transduction by protein phosphorylation);GO:0004675(transmembrane receptor protein serine/threonine kinase activity);GO:0007178(transmembrane receptor protein serine/threonine kinase signaling pathway);GO:0006468(protein phosphorylation);GO:0010628(positive regulation of gene expression);GO:0010718(positive regulation of epithelial to mesenchymal transition);GO:0051897(positive regulation of protein kinase B signaling);GO:0060412(ventricular septum morphogenesis);GO:0030335(positive regulation of cell migration);GO:0007179(transforming growth factor beta receptor signaling pathway);GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0005623(cell);GO:0005515(protein binding);GO:0006915(apoptotic process);GO:0030054(cell junction);GO:0030154(cell differentiation);GO:0045121(membrane raft);GO:0005923(bicellular tight junction);GO:0040008(regulation of growth);GO:0016579(protein deubiquitination);GO:0060037(pharyngeal system development);GO:0007050(cell cycle arrest);GO:0005025(transforming growth factor beta receptor activity, type I);GO:0005057(signal transducer activity, downstream of receptor);GO:0050431(transforming growth factor beta binding);GO:0001938(positive regulation of endothelial cell proliferation);GO:0007507(heart development);GO:0010468(regulation of gene expression);GO:0010717(regulation of epithelial to mesenchymal transition);GO:0032924(activin receptor signaling pathway);GO:0035556(intracellular signal transduction);GO:0042118(endothelial cell activation);GO:0045893(positive regulation of transcription, DNA-templated);GO:0048762(mesenchymal cell differentiation);GO:0060317(cardiac epithelial to mesenchymal transition);GO:0009986(cell surface);GO:0046332(SMAD binding);GO:0008284(positive regulation of cell proliferation);GO:0060021(palate development);GO:0030307(positive regulation of cell growth);GO:0048844(artery morphogenesis);GO:0060978(angiogenesis involved in coronary vascular morphogenesis);GO:0043235(receptor complex);GO:0032331(negative regulation of chondrocyte differentiation);GO:0042060(wound healing);GO:0051496(positive regulation of stress fiber assembly);GO:0030199(collagen fibril organization);GO:0070411(I-SMAD binding);GO:0030512(negative regulation of transforming growth factor beta receptor signaling pathway);GO:0060389(pathway-restricted SMAD protein phosphorylation);GO:0071560(cellular response to transforming growth factor beta stimulus);GO:0018107(peptidyl-threonine phosphorylation);GO:0001822(kidney development);GO:0010862(positive regulation of pathway-restricted SMAD protein phosphorylation);GO:0009952(anterior/posterior pattern specification);GO:0001837(epithelial to mesenchymal transition);GO:0018105(peptidyl-serine phosphorylation);GO:0005114(type II transforming growth factor beta receptor binding);GO:0060391(positive regulation of SMAD protein import into nucleus);GO:0070723(response to cholesterol);GO:2001235(positive regulation of apoptotic signaling pathway);GO:0001501(skeletal system development);GO:2001237(negative regulation of extrinsic apoptotic signaling pathway);GO:0006355(regulation of transcription, DNA-templated);GO:0001701(in utero embryonic development);GO:1905075(positive regulation of occluding junction disassembly);GO:0048870(cell motility);GO:0051272(positive regulation of cellular component movement);GO:0060982(coronary artery morphogenesis);GO:0003223(ventricular compact myocardium morphogenesis);GO:0003222(ventricular trabecula myocardium morphogenesis);GO:1905007(positive regulation of epithelial to mesenchymal transition involved in endocardial cushion formation);GO:0070022(transforming growth factor beta receptor complex);GO:0048701(embryonic cranial skeleton morphogenesis);GO:0031396(regulation of protein ubiquitination);GO:0060043(regulation of cardiac muscle cell proliferation);GO:0019838(growth factor binding);GO:0007165(signal transduction);GO:0005024(transforming growth factor beta-activated receptor activity);GO:0000186(activation of MAPKK activity);GO:0008354(germ cell migration);GO:0043062(extracellular structure organization);GO:0048538(thymus development);GO:0048663(neuron fate commitment);GO:0048705(skeletal system morphogenesis);GO:0060017(parathyroid gland development);GO:1905223(epicardium morphogenesis);GO:0005102(receptor binding);GO:0001525(angiogenesis);GO:0001824(blastocyst development);GO:0001937(negative regulation of endothelial cell proliferation);GO:0002088(lens development in camera-type eye);GO:0008584(male gonad development);GO:0009791(post-embryonic development);GO:0043065(positive regulation of apoptotic process);GO:0043066(negative regulation of apoptotic process);GO:0043393(regulation of protein binding);GO:0043542(endothelial cell migration);GO:0051491(positive regulation of filopodium assembly);GO:0005768(endosome)","04010(MAPK signaling pathway);04350(TGF-beta signaling pathway);04390(Hippo signaling pathway);04371(Apelin signaling pathway);04068(FoxO signaling pathway);04060(Cytokine-cytokine receptor interaction);04144(Endocytosis);04218(Cellular senescence);04520(Adherens junction);04659(Th17 cell differentiation);04926(Relaxin signaling pathway);04380(Osteoclast differentiation);05200(Pathways in cancer);05210(Colorectal cancer);05212(Pancreatic cancer);05225(Hepatocellular carcinoma);05226(Gastric cancer);05220(Chronic myeloid leukemia);04933(AGE-RAGE signaling pathway in diabetic complications);05166(HTLV-I infection);05161(Hepatitis B);05142(Chagas disease (American trypanosomiasis))","K04674","EC:2.7.11.30","transforming growth factor beta receptor 1 [Source:HGNC Symbol;Acc:HGNC:11772]",{"v":0.392129,"d":"0.39"},{"v":3.934019,"d":"3.93"},{"v":0.09967643775996,"d":"0.10"},{"v":-3.32660367957766,"d":"-3.33"},{"v":1.26150123473755e-06,"d":"0.00"},{"v":0.000137157068313114,"d":"0.00"},"down","yes"]
[166247,"j","chr6","-",43511827,43516979,"MSTRG.13067.1",8,2196,"MSTRG.13067","YIPF3","NA","NA","NA","NA","NA",{"v":0.923951,"d":"0.92"},{"v":9.326295,"d":"9.33"},{"v":0.0990694589866608,"d":"0.10"},{"v":-3.33541581611052,"d":"-3.34"},{"v":1.28243844088623e-06,"d":"0.00"},{"v":1.38671540263698E-4,"d":"0.00"},"down","yes"]
[70199,0,"chr16","-",18782968,18790334,"ENST00000569365",5,481,"MSTRG.5711","RPS15A","GO:0003723(RNA binding);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0006412(translation);GO:0030529(intracellular ribonucleoprotein complex);GO:0003735(structural constituent of ribosome);GO:0005840(ribosome);GO:0022627(cytosolic small ribosomal subunit);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0009615(response to virus);GO:0031012(extracellular matrix);GO:0005739(mitochondrion);GO:0005515(protein binding);GO:0008284(positive regulation of cell proliferation);GO:0006413(translational initiation);GO:0006364(rRNA processing);GO:0045787(positive regulation of cell cycle);GO:0000184(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay);GO:0019083(viral transcription);GO:0006614(SRP-dependent cotranslational protein targeting to membrane)","03010(Ribosome)","NA","NA","ribosomal protein S15a [Source:HGNC Symbol;Acc:HGNC:10389]",{"v":2.417841,"d":"2.42"},{"v":25.010029,"d":"25.01"},{"v":0.0966748579139992,"d":"0.10"},{"v":-3.37071545083819,"d":"-3.37"},{"v":1.36807149356903e-06,"d":"0.00"},{"v":0.000147127166927956,"d":"0.00"},"down","yes"]
[187973,"j","chr8","-",143577816,143597744,"MSTRG.14619.17",9,3074,"MSTRG.14619","NAPRT","NA","NA","NA","NA","NA",{"v":0.410274,"d":"0.41"},{"v":4.148687,"d":"4.15"},{"v":0.0988924929742832,"d":"0.10"},{"v":-3.33799518102324,"d":"-3.34"},{"v":1.44199891160716e-06,"d":"0.00"},{"v":0.000154239321420986,"d":"0.00"},"down","yes"]
[64108,0,"chr15","-",70049799,70097888,"ENST00000557997",20,3683,"MSTRG.5252","TLE3","GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0016055(Wnt signaling pathway);GO:0005515(protein binding);GO:0007165(signal transduction);GO:1904837(beta-catenin-TCF complex assembly);GO:0009887(animal organ morphogenesis)","NA","NA","NA","transducin like enhancer of split 3 [Source:HGNC Symbol;Acc:HGNC:11839]",{"v":12.349645,"d":"12.35"},{"v":0.961455,"d":"0.96"},{"v":12.8447457239288,"d":"12.84"},{"v":3.68310642565097,"d":"3.68"},{"v":1.52482587567422E-6,"d":"0.00"},{"v":0.000162221797999148,"d":"0.00"},"up","yes"]
[197899,0,"chrX","+",66015461,66020422,"ENST00000621933",3,1815,"MSTRG.15336","AL034397.3","NA","NA","NA","NA","NA",{"v":1.695281,"d":"1.70"},{"v":16.54575,"d":"16.55"},{"v":0.102460208814952,"d":"0.10"},{"v":-3.28686435775202,"d":"-3.29"},{"v":1.54703466973375E-6,"d":"0.00"},{"v":0.000163059669139486,"d":"0.00"},"down","yes"]
[182375,0,"chr8","+",26390362,26411048,"ENST00000518611",6,1352,"MSTRG.14248","BNIP3L","GO:0005634(nucleus);GO:0016607(nuclear speck);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005739(mitochondrion);GO:0005783(endoplasmic reticulum);GO:0042803(protein homodimerization activity);GO:0005515(protein binding);GO:0006915(apoptotic process);GO:0005741(mitochondrial outer membrane);GO:0042802(identical protein binding);GO:0051607(defense response to virus);GO:0043065(positive regulation of apoptotic process);GO:0005740(mitochondrial envelope);GO:0016032(viral process);GO:0043066(negative regulation of apoptotic process);GO:0042981(regulation of apoptotic process);GO:0046982(protein heterodimerization activity);GO:0005635(nuclear envelope);GO:0031224(intrinsic component of membrane);GO:0071456(cellular response to hypoxia);GO:0005521(lamin binding);GO:0010917(negative regulation of mitochondrial membrane potential);GO:0016239(positive regulation of macroautophagy);GO:0035694(mitochondrial protein catabolic process);GO:0035794(positive regulation of mitochondrial membrane permeability);GO:0060548(negative regulation of cell death);GO:0097345(mitochondrial outer membrane permeabilization);GO:1903146(regulation of mitophagy);GO:1903214(regulation of protein targeting to mitochondrion);GO:0005829(cytosol)","04137(Mitophagy - animal)","K15465","NA","BCL2 interacting protein 3 like [Source:HGNC Symbol;Acc:HGNC:1085]",{"v":4.236596,"d":"4.24"},{"v":40.817932,"d":"40.82"},{"v":0.103792519425041,"d":"0.10"},{"v":-3.26822562592468,"d":"-3.27"},{"v":1.54918222145863e-06,"d":"0.00"},{"v":0.000163059669139486,"d":"0.00"},"down","yes"]
[30861,0,"chr11","-",64765652,64777760,"ENST00000433274",13,2317,"MSTRG.2520","SF1","GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0006397(mRNA processing);GO:0008380(RNA splicing);GO:0005634(nucleus);GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0005654(nucleoplasm);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0005840(ribosome);GO:0005515(protein binding);GO:0005681(spliceosomal complex);GO:0045131(pre-mRNA branch point binding);GO:0000398(mRNA splicing, via spliceosome);GO:1903507(negative regulation of nucleic acid-templated transcription);GO:0042802(identical protein binding);GO:0003714(transcription corepressor activity);GO:0000245(spliceosomal complex assembly);GO:0000389(mRNA 3'-splice site recognition);GO:0030238(male sex determination);GO:0030575(nuclear body organization);GO:0033327(Leydig cell differentiation);GO:0048662(negative regulation of smooth muscle cell proliferation);GO:0050810(regulation of steroid biosynthetic process);GO:0016604(nuclear body)","NA","NA","NA","splicing factor 1 [Source:HGNC Symbol;Acc:HGNC:12950]",{"v":6.836946,"d":"6.84"},{"v":0.516337,"d":"0.52"},{"v":13.2412474798436,"d":"13.24"},{"v":3.72696714212338,"d":"3.73"},{"v":1.58972368442265e-06,"d":"0.00"},{"v":0.000166441546388124,"d":"0.00"},"up","yes"]
[147255,0,"chr4","-",48550502,48780248,"ENST00000507711",38,5277,"MSTRG.11602","FRYL","GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0005938(cell cortex);GO:0000902(cell morphogenesis);GO:0031175(neuron projection development);GO:0090527(actin filament reorganization);GO:0030427(site of polarized growth)","NA","NA","NA","FRY like transcription coactivator [Source:HGNC Symbol;Acc:HGNC:29127]",{"v":2.423236,"d":"2.42"},{"v":0.18044,"d":"0.18"},{"v":13.4295943249834,"d":"13.43"},{"v":3.74734382004182,"d":"3.75"},{"v":1.61721321260709e-06,"d":"0.00"},{"v":0.000168428500268784,"d":"0.00"},"up","yes"]
[42104,0,"chr12","+",53252096,53254404,"ENST00000329548",2,1760,"MSTRG.3386","MFSD5","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0015098(molybdate ion transmembrane transporter activity);GO:0015689(molybdate ion transport);GO:0006810(transport);GO:0006811(ion transport);GO:0005886(plasma membrane);GO:0005515(protein binding)","NA","NA","NA","major facilitator superfamily domain containing 5 [Source:HGNC Symbol;Acc:HGNC:28156]",{"v":0.649054,"d":"0.65"},{"v":6.542598,"d":"6.54"},{"v":0.0992043221973901,"d":"0.10"},{"v":-3.33345321153254,"d":"-3.33"},{"v":1.62657794879032e-06,"d":"0.00"},{"v":1.68516881940643E-4,"d":"0.00"},"down","yes"]
[154940,0,"chr5","-",55940966,55994792,"ENST00000503773",18,3031,"MSTRG.12062","IL6ST","GO:0008284(positive regulation of cell proliferation);GO:0042531(positive regulation of tyrosine phosphorylation of STAT protein);GO:0043066(negative regulation of apoptotic process);GO:0010613(positive regulation of cardiac muscle hypertrophy);GO:0002675(positive regulation of acute inflammatory response);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0004896(cytokine receptor activity);GO:0070062(extracellular exosome);GO:0016032(viral process);GO:0042803(protein homodimerization activity);GO:0035722(interleukin-12-mediated signaling pathway);GO:0045669(positive regulation of osteoblast differentiation);GO:0019838(growth factor binding);GO:0019221(cytokine-mediated signaling pathway);GO:0005127(ciliary neurotrophic factor receptor binding);GO:0010575(positive regulation of vascular endothelial growth factor production);GO:0042102(positive regulation of T cell proliferation);GO:0005138(interleukin-6 receptor binding);GO:0070102(interleukin-6-mediated signaling pathway);GO:0005896(interleukin-6 receptor complex);GO:0004897(ciliary neurotrophic factor receptor activity);GO:0004915(interleukin-6 receptor activity);GO:0019981(interleukin-6 binding);GO:0034097(response to cytokine);GO:0070120(ciliary neurotrophic factor-mediated signaling pathway);GO:0070110(ciliary neurotrophic factor receptor complex);GO:0038165(oncostatin-M-mediated signaling pathway);GO:0048861(leukemia inhibitory factor signaling pathway);GO:0004923(leukemia inhibitory factor receptor activity);GO:0004924(oncostatin-M receptor activity);GO:0004921(interleukin-11 receptor activity);GO:0019970(interleukin-11 binding);GO:0045509(interleukin-27 receptor activity);GO:0002821(positive regulation of adaptive immune response);GO:0005977(glycogen metabolic process);GO:0007165(signal transduction);GO:0008593(regulation of Notch signaling pathway);GO:0038154(interleukin-11-mediated signaling pathway);GO:0048711(positive regulation of astrocyte differentiation);GO:0070106(interleukin-27-mediated signaling pathway);GO:0005900(oncostatin-M receptor complex);GO:0009897(external side of plasma membrane);GO:0030425(dendrite);GO:0043025(neuronal cell body);GO:0044297(cell body)","04630(Jak-STAT signaling pathway);04060(Cytokine-cytokine receptor interaction);04550(Signaling pathways regulating pluripotency of stem cells);04659(Th17 cell differentiation);05200(Pathways in cancer);05203(Viral carcinogenesis);05167(Kaposi's sarcoma-associated herpesvirus infection)","NA","NA","interleukin 6 signal transducer [Source:HGNC Symbol;Acc:HGNC:6021]",{"v":4.211572,"d":"4.21"},{"v":0.316226,"d":"0.32"},{"v":13.3182344272767,"d":"13.32"},{"v":3.73533093466573,"d":"3.74"},{"v":1.64701525124289e-06,"d":"0.00"},{"v":0.000169745509331221,"d":"0.00"},"up","yes"]
[48237,0,"chr12","-",124911648,124915147,"ENST00000339647",2,2688,"MSTRG.3865","UBC","GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005515(protein binding);GO:0044322(endoplasmic reticulum quality control compartment);GO:0005615(extracellular space);GO:0038095(Fc-epsilon receptor signaling pathway);GO:0005886(plasma membrane);GO:0016567(protein ubiquitination);GO:0005789(endoplasmic reticulum membrane);GO:0006977(DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0034220(ion transmembrane transport);GO:0044267(cellular protein metabolic process);GO:0061024(membrane organization);GO:0016197(endosomal transport);GO:0019058(viral life cycle);GO:0075733(intracellular transport of virus);GO:0010008(endosome membrane);GO:0043657(host cell);GO:0000165(MAPK cascade);GO:0000209(protein polyubiquitination);GO:0002223(stimulatory C-type lectin receptor signaling pathway);GO:0010972(negative regulation of G2/M transition of mitotic cell cycle);GO:0016579(protein deubiquitination);GO:0031145(anaphase-promoting complex-dependent catabolic process);GO:0031146(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process);GO:0033209(tumor necrosis factor-mediated signaling pathway);GO:0038061(NIK/NF-kappaB signaling);GO:0043161(proteasome-mediated ubiquitin-dependent protein catabolic process);GO:0043488(regulation of mRNA stability);GO:0050852(T cell receptor signaling pathway);GO:0051437(positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition);GO:0055085(transmembrane transport);GO:0060071(Wnt signaling pathway, planar cell polarity pathway);GO:0061418(regulation of transcription from RNA polymerase II promoter in response to hypoxia);GO:0090090(negative regulation of canonical Wnt signaling pathway);GO:0090263(positive regulation of canonical Wnt signaling pathway);GO:1902036(regulation of hematopoietic stem cell differentiation);GO:0045087(innate immune response);GO:0000086(G2/M transition of mitotic cell cycle);GO:0036297(interstrand cross-link repair);GO:0006457(protein folding);GO:0002755(MyD88-dependent toll-like receptor signaling pathway);GO:0002756(MyD88-independent toll-like receptor signaling pathway);GO:0007249(I-kappaB kinase/NF-kappaB signaling);GO:0035666(TRIF-dependent toll-like receptor signaling pathway);GO:0002020(protease binding);GO:0051436(negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle);GO:1904380(endoplasmic reticulum mannose trimming);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:1901796(regulation of signal transduction by p53 class mediator);GO:0031982(vesicle);GO:0030666(endocytic vesicle membrane);GO:0005741(mitochondrial outer membrane);GO:0007219(Notch signaling pathway);GO:0016055(Wnt signaling pathway);GO:0042787(protein ubiquitination involved in ubiquitin-dependent protein catabolic process);GO:0038128(ERBB2 signaling pathway);GO:0007254(JNK cascade);GO:0043065(positive regulation of apoptotic process);GO:0010803(regulation of tumor necrosis factor-mediated signaling pathway);GO:0043066(negative regulation of apoptotic process);GO:0043123(positive regulation of I-kappaB kinase/NF-kappaB signaling);GO:0051092(positive regulation of NF-kappaB transcription factor activity);GO:0051403(stress-activated MAPK cascade);GO:0070423(nucleotide-binding oligomerization domain containing signaling pathway);GO:0019985(translesion synthesis);GO:0032480(negative regulation of type I interferon production);GO:0042059(negative regulation of epidermal growth factor receptor signaling pathway);GO:0030512(negative regulation of transforming growth factor beta receptor signaling pathway);GO:0005978(glycogen biosynthetic process);GO:0006283(transcription-coupled nucleotide-excision repair);GO:0008543(fibroblast growth factor receptor signaling pathway);GO:0000187(activation of MAPK activity);GO:0016236(macroautophagy);GO:0042276(error-prone translesion synthesis);GO:0035635(entry of bacterium into host cell);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0042769(DNA damage response, detection of DNA damage);GO:0007179(transforming growth factor beta receptor signaling pathway);GO:0006879(cellular iron ion homeostasis);GO:0006296(nucleotide-excision repair, DNA incision, 5'-to lesion);GO:0033683(nucleotide-excision repair, DNA incision);GO:0070911(global genome nucleotide-excision repair);GO:0000715(nucleotide-excision repair, DNA damage recognition);GO:0000717(nucleotide-excision repair, DNA duplex unwinding);GO:0006294(nucleotide-excision repair, preincision complex assembly);GO:0006297(nucleotide-excision repair, DNA gap filling);GO:0019068(virion assembly);GO:0032479(regulation of type I interferon production);GO:0045742(positive regulation of epidermal growth factor receptor signaling pathway);GO:0060544(regulation of necroptotic process);GO:0070987(error-free translesion synthesis)","03320(PPAR signaling pathway)","K08770","NA","ubiquitin C [Source:HGNC Symbol;Acc:HGNC:12468]",{"v":25.704542,"d":"25.70"},{"v":2.053574,"d":"2.05"},{"v":12.5169786917832,"d":"12.52"},{"v":3.64581446607173,"d":"3.65"},{"v":1.77540260862306E-6,"d":"0.00"},{"v":0.000182029361758721,"d":"0.00"},"up","yes"]
[79400,0,"chr17","-",9913850,10198551,"ENST00000432992",14,4970,"MSTRG.6445","GAS7","GO:0005737(cytoplasm);GO:0005515(protein binding);GO:0007275(multicellular organism development);GO:0007399(nervous system development);GO:0030154(cell differentiation);GO:0006355(regulation of transcription, DNA-templated);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0007050(cell cycle arrest)","NA","NA","NA","growth arrest specific 7 [Source:HGNC Symbol;Acc:HGNC:4169]",{"v":3.578589,"d":"3.58"},{"v":0.275257,"d":"0.28"},{"v":13.0009009761786,"d":"13.00"},{"v":3.70053970189678,"d":"3.70"},{"v":1.84112463037813e-06,"d":"0.00"},{"v":1.87794712298569E-4,"d":"0.00"},"up","yes"]
[3481,"j","chr1","+",28887099,29120040,"MSTRG.337.5",18,5721,"MSTRG.337","EPB41","NA","NA","NA","NA","NA",{"v":5.460836,"d":"5.46"},{"v":0.43159,"d":"0.43"},{"v":12.6528325494103,"d":"12.65"},{"v":3.66138848751736,"d":"3.66"},{"v":1.86229561994482E-6,"d":"0.00"},{"v":1.88052194800097E-4,"d":"0.00"},"up","yes"]
[71739,0,"chr16","+",30065772,30070352,"ENST00000569798",8,1499,"MSTRG.5821","ALDOA","GO:0070062(extracellular exosome);GO:0008360(regulation of cell shape);GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005829(cytosol);GO:0003824(catalytic activity);GO:0004332(fructose-bisphosphate aldolase activity);GO:0016829(lyase activity);GO:0006096(glycolytic process);GO:0005515(protein binding);GO:0005615(extracellular space);GO:0005576(extracellular region);GO:0045296(cadherin binding);GO:0031430(M band);GO:0031674(I band);GO:0043312(neutrophil degranulation);GO:0015629(actin cytoskeleton);GO:0002576(platelet degranulation);GO:0034774(secretory granule lumen);GO:1904813(ficolin-1-rich granule lumen);GO:0031093(platelet alpha granule lumen);GO:1904724(tertiary granule lumen);GO:0051289(protein homotetramerization);GO:0006094(gluconeogenesis);GO:0061621(canonical glycolysis);GO:0042802(identical protein binding);GO:0003779(actin binding);GO:0006754(ATP biosynthetic process);GO:0046716(muscle cell cellular homeostasis);GO:0008092(cytoskeletal protein binding);GO:0015631(tubulin binding);GO:0070061(fructose binding);GO:0006000(fructose metabolic process);GO:0006941(striated muscle contraction);GO:0007015(actin filament organization);GO:0030388(fructose 1,6-bisphosphate metabolic process);GO:0016021(integral component of membrane)","00010(Glycolysis / Gluconeogenesis);00030(Pentose phosphate pathway);00051(Fructose and mannose metabolism);04066(HIF-1 signaling pathway)","NA","NA","aldolase, fructose-bisphosphate A [Source:HGNC Symbol;Acc:HGNC:414]",{"v":3.168532,"d":"3.17"},{"v":30.004913,"d":"30.00"},{"v":0.105600439501358,"d":"0.11"},{"v":-3.24331225578655,"d":"-3.24"},{"v":1.86435469313221E-6,"d":"0.00"},{"v":1.88052194800097E-4,"d":"0.00"},"down","yes"]
[177205,0,"chr7","+",101816011,102258233,"ENST00000360264",24,13762,"ENSG00000257923","CUX1","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005794(Golgi apparatus);GO:0005654(nucleoplasm);GO:0000139(Golgi membrane);GO:0006891(intra-Golgi vesicle-mediated transport);GO:0030173(integral component of Golgi membrane);GO:0005634(nucleus);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0018108(peptidyl-tyrosine phosphorylation);GO:0043565(sequence-specific DNA binding);GO:0007275(multicellular organism development);GO:0005829(cytosol);GO:0000977(RNA polymerase II regulatory region sequence-specific DNA binding);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0004713(protein tyrosine kinase activity);GO:0048193(Golgi vesicle transport);GO:0050775(positive regulation of dendrite morphogenesis);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0030674(protein binding, bridging);GO:0000301(retrograde transport, vesicle recycling within Golgi)","NA","NA","NA","cut like homeobox 1 [Source:HGNC Symbol;Acc:HGNC:2557]",{"v":3.688191,"d":"3.69"},{"v":0.295011,"d":"0.30"},{"v":12.5018762012264,"d":"12.50"},{"v":3.64407271642163,"d":"3.64"},{"v":1.87215900422575e-06,"d":"0.00"},{"v":1.88052194800097E-4,"d":"0.00"},"up","yes"]
[192532,0,"chr9","-",109015152,109119945,"ENST00000374586",18,7980,"MSTRG.14893","TMEM245","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0003674(molecular_function);GO:0008150(biological_process)","NA","NA","NA","transmembrane protein 245 [Source:HGNC Symbol;Acc:HGNC:1363]",{"v":4.945804,"d":"4.95"},{"v":0.395111,"d":"0.40"},{"v":12.5175052073974,"d":"12.52"},{"v":3.64587515048358,"d":"3.65"},{"v":1.89096602579208e-06,"d":"0.00"},{"v":0.000188981998577645,"d":"0.00"},"up","yes"]
[127666,0,"chr21","+",43865186,43986536,"ENST00000291572",10,5546,"MSTRG.10072","AGPAT3","GO:0005634(nucleus);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016740(transferase activity);GO:0016746(transferase activity, transferring acyl groups);GO:0006629(lipid metabolic process);GO:0008152(metabolic process);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005886(plasma membrane);GO:0008654(phospholipid biosynthetic process);GO:0003841(1-acylglycerol-3-phosphate O-acyltransferase activity);GO:0016024(CDP-diacylglycerol biosynthetic process);GO:0000139(Golgi membrane);GO:0005635(nuclear envelope);GO:0006654(phosphatidic acid biosynthetic process);GO:0042171(lysophosphatidic acid acyltransferase activity)","00561(Glycerolipid metabolism);00564(Glycerophospholipid metabolism);04072(Phospholipase D signaling pathway)","K13523","EC:2.3.1.51;EC:2.3.1.-","1-acylglycerol-3-phosphate O-acyltransferase 3 [Source:HGNC Symbol;Acc:HGNC:326]",{"v":3.554196,"d":"3.55"},{"v":0.279821,"d":"0.28"},{"v":12.7016771436025,"d":"12.70"},{"v":3.66694709952318,"d":"3.67"},{"v":1.96465425021941e-06,"d":"0.00"},{"v":1.95359689966542E-4,"d":"0.00"},"up","yes"]
[70201,0,"chr16","-",18782969,18790260,"ENST00000565420",5,802,"MSTRG.5711","RPS15A","GO:0003723(RNA binding);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0006412(translation);GO:0030529(intracellular ribonucleoprotein complex);GO:0003735(structural constituent of ribosome);GO:0005840(ribosome);GO:0022627(cytosolic small ribosomal subunit);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0009615(response to virus);GO:0031012(extracellular matrix);GO:0005739(mitochondrion);GO:0005515(protein binding);GO:0008284(positive regulation of cell proliferation);GO:0006413(translational initiation);GO:0006364(rRNA processing);GO:0045787(positive regulation of cell cycle);GO:0000184(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay);GO:0019083(viral transcription);GO:0006614(SRP-dependent cotranslational protein targeting to membrane)","03010(Ribosome)","NA","NA","ribosomal protein S15a [Source:HGNC Symbol;Acc:HGNC:10389]",{"v":6.302811,"d":"6.30"},{"v":59.117317,"d":"59.12"},{"v":0.106615308675121,"d":"0.11"},{"v":-3.22951348827263,"d":"-3.23"},{"v":2.0019444968921e-06,"d":"0.00"},{"v":0.000197332050068672,"d":"0.00"},"down","yes"]
[6314,0,"chr1","+",54053601,54106082,"ENST00000234827",5,10436,"MSTRG.590","TCEANC2","GO:0005634(nucleus);GO:0006351(transcription, DNA-templated);GO:0005515(protein binding)","NA","NA","NA","transcription elongation factor A N-terminal and central domain containing 2 [Source:HGNC Symbol;Acc:HGNC:26494]",{"v":1.293637,"d":"1.29"},{"v":0.100369,"d":"0.10"},{"v":12.8888102900298,"d":"12.89"},{"v":3.6880471958338,"d":"3.69"},{"v":2.00443410469997e-06,"d":"0.00"},{"v":0.000197332050068672,"d":"0.00"},"up","yes"]
[136264,0,"chr3","-",49357178,49358283,"ENST00000419349",1,1106,"MSTRG.10926","GPX1","GO:0005737(cytoplasm);GO:0043154(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process);GO:0005829(cytosol);GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0098869(cellular oxidant detoxification);GO:0004601(peroxidase activity);GO:0004602(glutathione peroxidase activity);GO:0006979(response to oxidative stress);GO:0070062(extracellular exosome);GO:0005759(mitochondrial matrix);GO:0034599(cellular response to oxidative stress);GO:0019372(lipoxygenase pathway);GO:1902042(negative regulation of extrinsic apoptotic signaling pathway via death domain receptors);GO:0005739(mitochondrion);GO:0017124(SH3 domain binding);GO:0006195(purine nucleotide catabolic process);GO:0090201(negative regulation of release of cytochrome c from mitochondria);GO:0097413(Lewy body);GO:0042542(response to hydrogen peroxide);GO:0042744(hydrogen peroxide catabolic process);GO:0000302(response to reactive oxygen species);GO:0001659(temperature homeostasis);GO:0001885(endothelial cell development);GO:0002862(negative regulation of inflammatory response to antigenic stimulus);GO:0006629(lipid metabolic process);GO:0006641(triglyceride metabolic process);GO:0006749(glutathione metabolic process);GO:0006915(apoptotic process);GO:0007605(sensory perception of sound);GO:0008283(cell proliferation);GO:0008631(intrinsic apoptotic signaling pathway in response to oxidative stress);GO:0009410(response to xenobiotic stimulus);GO:0009609(response to symbiotic bacterium);GO:0009611(response to wounding);GO:0009636(response to toxic substance);GO:0009650(UV protection);GO:0010269(response to selenium ion);GO:0010332(response to gamma radiation);GO:0014902(myotube differentiation);GO:0018158(protein oxidation);GO:0033194(response to hydroperoxide);GO:0033599(regulation of mammary gland epithelial cell proliferation);GO:0040029(regulation of gene expression, epigenetic);GO:0042311(vasodilation);GO:0043066(negative regulation of apoptotic process);GO:0043403(skeletal muscle tissue regeneration);GO:0043523(regulation of neuron apoptotic process);GO:0043534(blood vessel endothelial cell migration);GO:0045444(fat cell differentiation);GO:0045454(cell redox homeostasis);GO:0048741(skeletal muscle fiber development);GO:0051450(myoblast proliferation);GO:0051702(interaction with symbiont);GO:0051897(positive regulation of protein kinase B signaling);GO:0060047(heart contraction);GO:0060055(angiogenesis involved in wound healing);GO:0061136(regulation of proteasomal protein catabolic process);GO:1902176(negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway);GO:1902905(positive regulation of supramolecular fiber organization)","00590(Arachidonic acid metabolism);00480(Glutathione metabolism);04918(Thyroid hormone synthesis);05014(Amyotrophic lateral sclerosis (ALS));05016(Huntington's disease)","K00432","EC:1.11.1.9","glutathione peroxidase 1 [Source:HGNC Symbol;Acc:HGNC:4553]",{"v":1.316206,"d":"1.32"},{"v":12.774863,"d":"12.77"},{"v":0.103030928785694,"d":"0.10"},{"v":-3.27885061080191,"d":"-3.28"},{"v":2.07152218256109e-06,"d":"0.00"},{"v":2.01223694075284E-4,"d":"0.00"},"down","yes"]
[167743,"j","chr6","+",89080713,89084839,"MSTRG.13160.1",3,1704,"MSTRG.13160","PNRC1","NA","NA","NA","NA","NA",{"v":92.365547,"d":"92.37"},{"v":7.5818,"d":"7.58"},{"v":12.182535413754,"d":"12.18"},{"v":3.60674251123438,"d":"3.61"},{"v":2.07186810144544E-6,"d":"0.00"},{"v":2.01223694075284E-4,"d":"0.00"},"up","yes"]
[197969,0,"chrX","-",69160891,69165793,"ENST00000374571",2,2672,"ENSG00000181191","PJA1","GO:0016567(protein ubiquitination);GO:0061630(ubiquitin protein ligase activity);GO:0046872(metal ion binding);GO:0016740(transferase activity);GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0030163(protein catabolic process)","NA","NA","NA","praja ring finger ubiquitin ligase 1 [Source:HGNC Symbol;Acc:HGNC:16648]",{"v":0.322324,"d":"0.32"},{"v":3.238842,"d":"3.24"},{"v":0.0995182846214789,"d":"0.10"},{"v":-3.32889457156318,"d":"-3.33"},{"v":2.08236663080453e-06,"d":"0.00"},{"v":2.01223694075284E-4,"d":"0.00"},"down","yes"]
[200501,0,"chrX","+",147911951,147951125,"ENST00000440235",16,4271,"MSTRG.15471","FMR1","GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0006397(mRNA processing);GO:0006810(transport);GO:0008380(RNA splicing);GO:0051028(mRNA transport);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005829(cytosol);GO:0030529(intracellular ribonucleoprotein complex);GO:0005694(chromosome);GO:0042803(protein homodimerization activity);GO:0005886(plasma membrane);GO:0042995(cell projection);GO:0005515(protein binding);GO:0006974(cellular response to DNA damage stimulus);GO:0048471(perinuclear region of cytoplasm);GO:0030054(cell junction);GO:0045202(synapse);GO:0045211(postsynaptic membrane);GO:0007399(nervous system development);GO:0005654(nucleoplasm);GO:0043022(ribosome binding);GO:0045727(positive regulation of translation);GO:0005730(nucleolus);GO:0031047(gene silencing by RNA);GO:0030425(dendrite);GO:0008017(microtubule binding);GO:0000775(chromosome, centromeric region);GO:0003729(mRNA binding);GO:0030424(axon);GO:0030426(growth cone);GO:0043204(perikaryon);GO:0098586(cellular response to virus);GO:0006417(regulation of translation);GO:0003682(chromatin binding);GO:0044325(ion channel binding);GO:0070840(dynein complex binding);GO:0042802(identical protein binding);GO:2000637(positive regulation of gene silencing by miRNA);GO:0005845(mRNA cap binding complex);GO:0014069(postsynaptic density);GO:0043197(dendritic spine);GO:0016032(viral process);GO:0043005(neuron projection);GO:0046982(protein heterodimerization activity);GO:0042734(presynaptic membrane);GO:0000381(regulation of alternative mRNA splicing, via spliceosome);GO:0003730(mRNA 3'-UTR binding);GO:0051491(positive regulation of filopodium assembly);GO:0031369(translation initiation factor binding);GO:0033592(RNA strand annealing activity);GO:0035613(RNA stem-loop binding);GO:0048027(mRNA 5'-UTR binding);GO:0036464(cytoplasmic ribonucleoprotein granule);GO:0035064(methylated histone binding);GO:1901386(negative regulation of voltage-gated calcium channel activity);GO:0032797(SMN complex);GO:0015030(Cajal body);GO:0030371(translation repressor activity);GO:0045947(negative regulation of translational initiation);GO:0060999(positive regulation of dendritic spine development);GO:0051489(regulation of filopodium assembly);GO:0005844(polysome);GO:0034644(cellular response to UV);GO:2001022(positive regulation of response to DNA damage stimulus);GO:0008266(poly(U) RNA binding);GO:0002092(positive regulation of receptor internalization);GO:0032433(filopodium tip);GO:0019897(extrinsic component of plasma membrane);GO:0043679(axon terminus);GO:0035198(miRNA binding);GO:0043488(regulation of mRNA stability);GO:0046928(regulation of neurotransmitter secretion);GO:0072711(cellular response to hydroxyurea);GO:0033129(positive regulation of histone phosphorylation);GO:0002151(G-quadruplex RNA binding);GO:0042788(polysomal ribosome);GO:0034046(poly(G) binding);GO:0098908(regulation of neuronal action potential);GO:0060998(regulation of dendritic spine development);GO:1990904(ribonucleoprotein complex);GO:0035197(siRNA binding);GO:1990825(sequence-specific mRNA binding);GO:0007215(glutamate receptor signaling pathway);GO:0044830(modulation by host of viral RNA genome replication);GO:0060964(regulation of gene silencing by miRNA);GO:1900453(negative regulation of long term synaptic depression);GO:1901254(positive regulation of intracellular transport of viral material);GO:1901800(positive regulation of proteasomal protein catabolic process);GO:1902373(negative regulation of mRNA catabolic process);GO:1902416(positive regulation of mRNA binding);GO:2000301(negative regulation of synaptic vesicle exocytosis);GO:2000766(negative regulation of cytoplasmic translation);GO:0010369(chromocenter);GO:0019034(viral replication complex);GO:0071598(neuronal ribonucleoprotein granule);GO:0097386(glial cell projection);GO:0098793(presynapse);GO:0098794(postsynapse);GO:1902737(dendritic filopodium);GO:1990124(messenger ribonucleoprotein complex);GO:1990812(growth cone filopodium)","03013(RNA transport)","K15516","NA","fragile X mental retardation 1 [Source:HGNC Symbol;Acc:HGNC:3775]",{"v":0.233517,"d":"0.23"},{"v":2.291146,"d":"2.29"},{"v":0.101921483833854,"d":"0.10"},{"v":-3.29446990841128,"d":"-3.29"},{"v":2.08464004878882e-06,"d":"0.00"},{"v":2.01223694075284E-4,"d":"0.00"},"down","yes"]
[150186,0,"chr4","-",112274542,112285903,"ENST00000361717",2,4157,"MSTRG.11799","TIFA","GO:0005622(intracellular);GO:0005515(protein binding);GO:0007249(I-kappaB kinase/NF-kappaB signaling)","NA","NA","NA","TRAF interacting protein with forkhead associated domain [Source:HGNC Symbol;Acc:HGNC:19075]",{"v":0.404301,"d":"0.40"},{"v":3.87465,"d":"3.87"},{"v":0.104345166660214,"d":"0.10"},{"v":-3.26056431946709,"d":"-3.26"},{"v":2.1387380526397E-6,"d":"0.00"},{"v":0.000204937462107727,"d":"0.00"},"down","yes"]
[133677,0,"chr3","+",15003915,15049273,"ENST00000617312",14,8113,"MSTRG.10686","NR2C2","GO:0005634(nucleus);GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0005654(nucleoplasm);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0043565(sequence-specific DNA binding);GO:0003707(steroid hormone receptor activity);GO:0043401(steroid hormone mediated signaling pathway);GO:0030154(cell differentiation);GO:0007283(spermatogenesis);GO:0005515(protein binding);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0001228(transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding);GO:0007399(nervous system development);GO:0003713(transcription coactivator activity);GO:0004872(receptor activity);GO:0046982(protein heterodimerization activity);GO:0006367(transcription initiation from RNA polymerase II promoter);GO:0001077(transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0000977(RNA polymerase II regulatory region sequence-specific DNA binding)","NA","NA","NA","nuclear receptor subfamily 2 group C member 2 [Source:HGNC Symbol;Acc:HGNC:7972]",{"v":4.109866,"d":"4.11"},{"v":0.331123,"d":"0.33"},{"v":12.4119013176373,"d":"12.41"},{"v":3.63365222658615,"d":"3.63"},{"v":2.14382730221849e-06,"d":"0.00"},{"v":0.000204937462107727,"d":"0.00"},"up","yes"]
[38299,0,"chr12","+",7132386,7158932,"ENST00000537408",17,4296,"MSTRG.3093","CLSTN3","GO:0016020(membrane);GO:0005509(calcium ion binding);GO:0016021(integral component of membrane);GO:0007155(cell adhesion);GO:0007156(homophilic cell adhesion via plasma membrane adhesion molecules);GO:0005794(Golgi apparatus);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005886(plasma membrane);GO:0000139(Golgi membrane);GO:0070062(extracellular exosome);GO:0001558(regulation of cell growth);GO:0007416(synapse assembly);GO:0035249(synaptic transmission, glutamatergic);GO:0050806(positive regulation of synaptic transmission);GO:0051932(synaptic transmission, GABAergic);GO:0051965(positive regulation of synapse assembly);GO:1902474(positive regulation of protein localization to synapse);GO:0009986(cell surface);GO:0014069(postsynaptic density);GO:0043234(protein complex);GO:0045211(postsynaptic membrane)","NA","NA","NA","calsyntenin 3 [Source:HGNC Symbol;Acc:HGNC:18371]",{"v":2.904571,"d":"2.90"},{"v":0.223662,"d":"0.22"},{"v":12.9864304173261,"d":"12.99"},{"v":3.69893302629497,"d":"3.70"},{"v":2.20543498425686e-06,"d":"0.00"},{"v":0.000209813208983052,"d":"0.00"},"up","yes"]
[129021,0,"chr22","+",21549447,21624034,"ENST00000458578",4,3007,"MSTRG.10166","UBE2L3","GO:0005737(cytoplasm);GO:0003723(RNA binding);GO:0005634(nucleus);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0005829(cytosol);GO:0016740(transferase activity);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0016567(protein ubiquitination);GO:0005515(protein binding);GO:0006511(ubiquitin-dependent protein catabolic process);GO:0003713(transcription coactivator activity);GO:0005654(nucleoplasm);GO:0070062(extracellular exosome);GO:0061631(ubiquitin conjugating enzyme activity);GO:0008283(cell proliferation);GO:0031625(ubiquitin protein ligase binding);GO:0019899(enzyme binding);GO:0004842(ubiquitin-protein transferase activity);GO:0006464(cellular protein modification process);GO:0070979(protein K11-linked ubiquitination);GO:0000151(ubiquitin ligase complex);GO:1903955(positive regulation of protein targeting to mitochondrion);GO:0000209(protein polyubiquitination);GO:0031398(positive regulation of protein ubiquitination);GO:0071383(cellular response to steroid hormone stimulus);GO:0044770(cell cycle phase transition);GO:0071385(cellular response to glucocorticoid stimulus);GO:0097027(ubiquitin-protein transferase activator activity);GO:0051443(positive regulation of ubiquitin-protein transferase activity)","04120(Ubiquitin mediated proteolysis);05012(Parkinson's disease)","K04552","EC:2.3.2.23","ubiquitin conjugating enzyme E2 L3 [Source:HGNC Symbol;Acc:HGNC:12488]",{"v":0.50014,"d":"0.50"},{"v":4.786715,"d":"4.79"},{"v":0.104485017386663,"d":"0.10"},{"v":-3.25863201278839,"d":"-3.26"},{"v":2.21717850288827e-06,"d":"0.00"},{"v":0.000209921187632311,"d":"0.00"},"down","yes"]
[110533,0,"chr2","-",69457997,69509280,"ENST00000606389",5,8964,"MSTRG.8788","AAK1","GO:0004672(protein kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0016020(membrane);GO:0000166(nucleotide binding);GO:0004674(protein serine/threonine kinase activity);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0005905(clathrin-coated pit);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0006897(endocytosis);GO:0031252(cell leading edge);GO:0050821(protein stabilization);GO:0061024(membrane organization);GO:0030136(clathrin-coated vesicle);GO:0046777(protein autophosphorylation);GO:0005112(Notch binding);GO:0045747(positive regulation of Notch signaling pathway);GO:0032880(regulation of protein localization);GO:0019897(extrinsic component of plasma membrane);GO:2000369(regulation of clathrin-dependent endocytosis);GO:0043195(terminal bouton);GO:0035612(AP-2 adaptor complex binding)","NA","NA","NA","AP2 associated kinase 1 [Source:HGNC Symbol;Acc:HGNC:19679]",{"v":5.601273,"d":"5.60"},{"v":0.459485,"d":"0.46"},{"v":12.1903283023385,"d":"12.19"},{"v":3.60766507513406,"d":"3.61"},{"v":2.25897426759756E-6,"d":"0.00"},{"v":2.12859918129622E-4,"d":"0.00"},"up","yes"]
[101376,0,"chr19","-",39825715,39834158,"ENST00000430012",11,2007,"MSTRG.8126","DYRK1B","GO:0005634(nucleus);GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0004713(protein tyrosine kinase activity);GO:0018108(peptidyl-tyrosine phosphorylation);GO:0007520(myoblast fusion);GO:0005515(protein binding);GO:0003713(transcription coactivator activity);GO:0045893(positive regulation of transcription, DNA-templated);GO:0060612(adipose tissue development);GO:0004712(protein serine/threonine/tyrosine kinase activity)","NA","NA","NA","dual specificity tyrosine phosphorylation regulated kinase 1B [Source:HGNC Symbol;Acc:HGNC:3092]",{"v":6.045052,"d":"6.05"},{"v":0.471612,"d":"0.47"},{"v":12.8178502667447,"d":"12.82"},{"v":3.68008241694019,"d":"3.68"},{"v":2.29147681921521e-06,"d":"0.00"},{"v":2.14899257339481E-4,"d":"0.00"},"up","yes"]
[119019,"j","chr2","-",218273735,218292579,"MSTRG.9420.2",13,3002,"MSTRG.9420","TMBIM1","NA","NA","NA","NA","NA",{"v":3.705318,"d":"3.71"},{"v":33.77179,"d":"33.77"},{"v":0.109716363864634,"d":"0.11"},{"v":-3.18814937948597,"d":"-3.19"},{"v":2.36029469747727e-06,"d":"0.00"},{"v":0.000220294590103871,"d":"0.00"},"down","yes"]
[21413,0,"chr10","+",74838700,75032622,"ENST00000372711",17,7560,"ENSG00000156650","KAT6B","GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0016740(transferase activity);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0016569(covalent chromatin modification);GO:0003677(DNA binding);GO:0016746(transferase activity, transferring acyl groups);GO:0006334(nucleosome assembly);GO:0000786(nucleosome);GO:0016747(transferase activity, transferring acyl groups other than amino-acyl groups);GO:0004402(histone acetyltransferase activity);GO:0045893(positive regulation of transcription, DNA-templated);GO:0005515(protein binding);GO:0005654(nucleoplasm);GO:0008134(transcription factor binding);GO:0045892(negative regulation of transcription, DNA-templated);GO:0043966(histone H3 acetylation);GO:0070776(MOZ/MORF histone acetyltransferase complex);GO:0016407(acetyltransferase activity);GO:0016573(histone acetylation);GO:0032403(protein complex binding);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:1990830(cellular response to leukemia inhibitory factor)","NA","NA","NA","lysine acetyltransferase 6B [Source:HGNC Symbol;Acc:HGNC:17582]",{"v":0.134008,"d":"0.13"},{"v":1.290682,"d":"1.29"},{"v":0.103827278911459,"d":"0.10"},{"v":-3.26774255697316,"d":"-3.27"},{"v":2.37127287710352E-6,"d":"0.00"},{"v":0.000220294590103871,"d":"0.00"},"down","yes"]
[147388,0,"chr4","+",52712781,52714137,"ENST00000425653",2,823,"MSTRG.11604","DANCR","NA","NA","NA","NA","differentiation antagonizing non-protein coding RNA [Source:HGNC Symbol;Acc:HGNC:28964]",{"v":1.236114,"d":"1.24"},{"v":11.986929,"d":"11.99"},{"v":0.10312182544837,"d":"0.10"},{"v":-3.27757838745995,"d":"-3.28"},{"v":2.43014995355524e-06,"d":"0.00"},{"v":2.23669471235448E-4,"d":"0.00"},"down","yes"]
[87304,0,"chr17","-",68268197,68291266,"ENST00000580666",6,2659,"MSTRG.7158","SLC16A6","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0055085(transmembrane transport);GO:0015293(symporter activity);GO:0005886(plasma membrane);GO:0005887(integral component of plasma membrane);GO:0008028(monocarboxylic acid transmembrane transporter activity);GO:0015718(monocarboxylic acid transport)","NA","NA","NA","solute carrier family 16 member 6 [Source:HGNC Symbol;Acc:HGNC:10927]",{"v":3.82887,"d":"3.83"},{"v":0.297714,"d":"0.30"},{"v":12.8609000584454,"d":"12.86"},{"v":3.6849197067925,"d":"3.68"},{"v":2.430207010088e-06,"d":"0.00"},{"v":2.23669471235448E-4,"d":"0.00"},"up","yes"]
[81825,0,"chr17","-",31317560,31321884,"ENST00000462804",2,1854,"MSTRG.6660","EVI2A","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0007165(signal transduction);GO:0004888(transmembrane signaling receptor activity)","NA","NA","NA","ecotropic viral integration site 2A [Source:HGNC Symbol;Acc:HGNC:3499]",{"v":10.311298,"d":"10.31"},{"v":93.08976,"d":"93.09"},{"v":0.110767263767787,"d":"0.11"},{"v":-3.17439652557734,"d":"-3.17"},{"v":2.4718860513604e-06,"d":"0.00"},{"v":0.000224689414690011,"d":"0.00"},"down","yes"]
[49288,0,"chr13","-",27435643,27450574,"ENST00000381120",5,1005,"MSTRG.3923","MTIF3","GO:0003743(translation initiation factor activity);GO:0006412(translation);GO:0006413(translational initiation);GO:0005739(mitochondrion);GO:0005515(protein binding);GO:0043022(ribosome binding);GO:0032790(ribosome disassembly);GO:0008135(translation factor activity, RNA binding);GO:0043024(ribosomal small subunit binding);GO:0070124(mitochondrial translational initiation)","NA","NA","NA","mitochondrial translational initiation factor 3 [Source:HGNC Symbol;Acc:HGNC:29788]",{"v":11.537728,"d":"11.54"},{"v":0.895022,"d":"0.90"},{"v":12.8909993273908,"d":"12.89"},{"v":3.68829220255802,"d":"3.69"},{"v":2.47286179739975e-06,"d":"0.00"},{"v":0.000224689414690011,"d":"0.00"},"up","yes"]
[18459,0,"chr10","+",11165140,11330639,"ENST00000608830",14,1892,"MSTRG.1548","CELF2","GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0006397(mRNA processing);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0006396(RNA processing);GO:0006376(mRNA splice site selection);GO:0008016(regulation of heart contraction);GO:0036002(pre-mRNA binding)","NA","NA","NA","CUGBP Elav-like family member 2 [Source:HGNC Symbol;Acc:HGNC:2550]",{"v":19.513187,"d":"19.51"},{"v":1.605675,"d":"1.61"},{"v":12.1526379871394,"d":"12.15"},{"v":3.60319761018904,"d":"3.60"},{"v":2.48395891688473E-6,"d":"0.00"},{"v":0.000224689414690011,"d":"0.00"},"up","yes"]
[110812,0,"chr2","-",70295975,70302090,"ENST00000037869",3,1810,"MSTRG.8798","FAM136A","GO:0005737(cytoplasm)","NA","NA","NA","family with sequence similarity 136 member A [Source:HGNC Symbol;Acc:HGNC:25911]",{"v":0.746979,"d":"0.75"},{"v":7.082905,"d":"7.08"},{"v":0.105462236186988,"d":"0.11"},{"v":-3.24520160229579,"d":"-3.25"},{"v":2.48670819775179e-06,"d":"0.00"},{"v":0.000224689414690011,"d":"0.00"},"down","yes"]
[191960,0,"chr9","-",95444162,95507417,"ENST00000429896",24,6563,"ENSG00000185920","PTCH1","GO:0048471(perinuclear region of cytoplasm);GO:0043433(negative regulation of sequence-specific DNA binding transcription factor activity);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005515(protein binding);GO:0007224(smoothened signaling pathway);GO:0060037(pharyngeal system development);GO:0005886(plasma membrane);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0030666(endocytic vesicle membrane);GO:0009887(animal organ morphogenesis);GO:0009953(dorsal/ventral pattern formation);GO:0005901(caveola);GO:0005794(Golgi apparatus);GO:0045668(negative regulation of osteoblast differentiation);GO:0071397(cellular response to cholesterol);GO:0015485(cholesterol binding);GO:0040015(negative regulation of multicellular organism growth);GO:0010875(positive regulation of cholesterol efflux);GO:0072001(renal system development);GO:0007420(brain development);GO:0043231(intracellular membrane-bounded organelle);GO:0060170(ciliary membrane);GO:0008589(regulation of smoothened signaling pathway);GO:0016485(protein processing);GO:0045879(negative regulation of smoothened signaling pathway);GO:0061053(somite development);GO:0072661(protein targeting to plasma membrane);GO:0030326(embryonic limb morphogenesis);GO:0030332(cyclin binding);GO:0005113(patched binding);GO:0005119(smoothened binding);GO:0008158(hedgehog receptor activity);GO:0008201(heparin binding);GO:0032403(protein complex binding);GO:0097108(hedgehog family protein binding);GO:0001658(branching involved in ureteric bud morphogenesis);GO:0001701(in utero embryonic development);GO:0001709(cell fate determination);GO:0001841(neural tube formation);GO:0001843(neural tube closure);GO:0003007(heart morphogenesis);GO:0007165(signal transduction);GO:0007346(regulation of mitotic cell cycle);GO:0007389(pattern specification process);GO:0008285(negative regulation of cell proliferation);GO:0008544(epidermis development);GO:0009612(response to mechanical stimulus);GO:0009957(epidermal cell fate specification);GO:0010157(response to chlorate);GO:0014070(response to organic cyclic compound);GO:0021522(spinal cord motor neuron differentiation);GO:0021532(neural tube patterning);GO:0021904(dorsal/ventral neural tube patterning);GO:0021997(neural plate axis specification);GO:0030850(prostate gland development);GO:0030879(mammary gland development);GO:0032355(response to estradiol);GO:0032526(response to retinoic acid);GO:0032880(regulation of protein localization);GO:0035108(limb morphogenesis);GO:0035137(hindlimb morphogenesis);GO:0040008(regulation of growth);GO:0042127(regulation of cell proliferation);GO:0042493(response to drug);GO:0042593(glucose homeostasis);GO:0043616(keratinocyte proliferation);GO:0045606(positive regulation of epidermal cell differentiation);GO:0045892(negative regulation of transcription, DNA-templated);GO:0045893(positive regulation of transcription, DNA-templated);GO:0048568(embryonic organ development);GO:0050680(negative regulation of epithelial cell proliferation);GO:0051782(negative regulation of cell division);GO:0060603(mammary gland duct morphogenesis);GO:0060644(mammary gland epithelial cell differentiation);GO:0060831(smoothened signaling pathway involved in dorsal/ventral neural tube patterning);GO:0061005(cell differentiation involved in kidney development);GO:0071679(commissural neuron axon guidance);GO:0072203(cell proliferation involved in metanephros development);GO:0005634(nucleus);GO:0005929(cilium);GO:0014069(postsynaptic density);GO:0030496(midbody);GO:0044294(dendritic growth cone);GO:0044295(axonal growth cone)","04340(Hedgehog signaling pathway);04024(cAMP signaling pathway);04360(Axon guidance);05200(Pathways in cancer);05205(Proteoglycans in cancer);05217(Basal cell carcinoma)","K06225","NA","patched 1 [Source:HGNC Symbol;Acc:HGNC:9585]",{"v":2.933237,"d":"2.93"},{"v":0.236941,"d":"0.24"},{"v":12.3796092698182,"d":"12.38"},{"v":3.62989387523991,"d":"3.63"},{"v":2.54602217227021e-06,"d":"0.00"},{"v":0.00022900312156765,"d":"0.00"},"up","yes"]
[4598,0,"chr1","-",39678648,39691689,"ENST00000372844",4,4856,"ENSG00000116983","HPCAL4","GO:0046872(metal ion binding);GO:0005509(calcium ion binding);GO:0007165(signal transduction);GO:0005515(protein binding);GO:0065009(regulation of molecular function);GO:0005246(calcium channel regulator activity);GO:0007417(central nervous system development);GO:0005622(intracellular);GO:0008022(protein C-terminus binding);GO:0019904(protein domain specific binding)","NA","NA","NA","hippocalcin like 4 [Source:HGNC Symbol;Acc:HGNC:18212]",{"v":0.154087,"d":"0.15"},{"v":1.505001,"d":"1.51"},{"v":0.102383320675534,"d":"0.10"},{"v":-3.28794739066916,"d":"-3.29"},{"v":2.58358123501845E-6,"d":"0.00"},{"v":0.000231308457016464,"d":"0.00"},"down","yes"]
[57932,0,"chr14","-",92936914,93115803,"ENST00000267615",11,6066,"MSTRG.4628","ITPK1","GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0016853(isomerase activity);GO:0016740(transferase activity);GO:0000287(magnesium ion binding);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0016787(hydrolase activity);GO:0005622(intracellular);GO:0016311(dephosphorylation);GO:0047325(inositol tetrakisphosphate 1-kinase activity);GO:0052725(inositol-1,3,4-trisphosphate 6-kinase activity);GO:0052726(inositol-1,3,4-trisphosphate 5-kinase activity);GO:0021915(neural tube development);GO:0032957(inositol trisphosphate metabolic process);GO:0016324(apical plasma membrane);GO:0005829(cytosol);GO:0007165(signal transduction);GO:0043647(inositol phosphate metabolic process);GO:0003824(catalytic activity);GO:0007596(blood coagulation);GO:0052659(inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity);GO:0052825(inositol-1,3,4,5,6-pentakisphosphate 1-phosphatase activity);GO:0052830(inositol-1,3,4,6-tetrakisphosphate 6-phosphatase activity);GO:0052831(inositol-1,3,4,6-tetrakisphosphate 1-phosphatase activity);GO:0052835(inositol-3,4,6-trisphosphate 1-kinase activity)","00562(Inositol phosphate metabolism);04070(Phosphatidylinositol signaling system)","K00913","EC:2.7.1.159;EC:2.7.1.134","inositol-tetrakisphosphate 1-kinase [Source:HGNC Symbol;Acc:HGNC:6177]",{"v":21.24004,"d":"21.24"},{"v":1.786471,"d":"1.79"},{"v":11.8893841545707,"d":"11.89"},{"v":3.57160208329666,"d":"3.57"},{"v":2.59503120364134e-06,"d":"0.00"},{"v":0.000231308457016464,"d":"0.00"},"up","yes"]
[50086,0,"chr13","-",45337198,45341122,"ENST00000379060",6,764,"MSTRG.3983","TPT1","GO:0003723(RNA binding);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005515(protein binding);GO:0006816(calcium ion transport);GO:0005509(calcium ion binding);GO:0070062(extracellular exosome);GO:0008017(microtubule binding);GO:0009615(response to virus);GO:0030154(cell differentiation);GO:0042981(regulation of apoptotic process);GO:0043066(negative regulation of apoptotic process);GO:0005615(extracellular space);GO:0005634(nucleus);GO:0006874(cellular calcium ion homeostasis);GO:0045298(tubulin complex);GO:1902230(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage);GO:0005771(multivesicular body)","NA","NA","NA","tumor protein, translationally-controlled 1 [Source:HGNC Symbol;Acc:HGNC:12022]",{"v":6.022614,"d":"6.02"},{"v":54.539665,"d":"54.54"},{"v":0.110426310832676,"d":"0.11"},{"v":-3.17884413667207,"d":"-3.18"},{"v":2.64404845519126e-06,"d":"0.00"},{"v":0.000233878750845238,"d":"0.00"},"down","yes"]
[184417,0,"chr8","-",66628487,66667217,"ENST00000310421",3,9942,"MSTRG.14381","VCPIP1","GO:0016787(hydrolase activity);GO:0016567(protein ubiquitination);GO:0005794(Golgi apparatus);GO:0005783(endoplasmic reticulum);GO:0008233(peptidase activity);GO:0008234(cysteine-type peptidase activity);GO:0006508(proteolysis);GO:0036459(thiol-dependent ubiquitinyl hydrolase activity);GO:0005737(cytoplasm);GO:0016579(protein deubiquitination);GO:0004843(thiol-dependent ubiquitin-specific protease activity);GO:0071108(protein K48-linked deubiquitination);GO:0005795(Golgi stack);GO:0005788(endoplasmic reticulum lumen);GO:0035871(protein K11-linked deubiquitination);GO:0000278(mitotic cell cycle);GO:0007030(Golgi organization);GO:0016320(endoplasmic reticulum membrane fusion);GO:0090168(Golgi reassembly)","NA","NA","NA","valosin containing protein interacting protein 1 [Source:HGNC Symbol;Acc:HGNC:30897]",{"v":0.406218,"d":"0.41"},{"v":3.691799,"d":"3.69"},{"v":0.110032534273941,"d":"0.11"},{"v":-3.18399793390244,"d":"-3.18"},{"v":2.64750556849269e-06,"d":"0.00"},{"v":0.000233878750845238,"d":"0.00"},"down","yes"]
[94562,"j","chr19","-",2101350,2137093,"MSTRG.7630.5",28,4164,"MSTRG.7630","AP3D1","NA","NA","NA","NA","NA",{"v":0.242812,"d":"0.24"},{"v":2.307732,"d":"2.31"},{"v":0.105216723605687,"d":"0.11"},{"v":-3.2485640637794,"d":"-3.25"},{"v":2.71411325150813e-06,"d":"0.00"},{"v":0.000238697213425968,"d":"0.00"},"down","yes"]
[159184,0,"chr5","-",140631728,140633701,"ENST00000302014",2,1886,"MSTRG.12388","CD14","GO:0016020(membrane);GO:0005794(Golgi apparatus);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0005615(extracellular space);GO:0031225(anchored component of membrane);GO:0045121(membrane raft);GO:0002376(immune system process);GO:0045087(innate immune response);GO:0006954(inflammatory response);GO:0070062(extracellular exosome);GO:0071222(cellular response to lipopolysaccharide);GO:0010008(endosome membrane);GO:0043312(neutrophil degranulation);GO:0006915(apoptotic process);GO:0002224(toll-like receptor signaling pathway);GO:0002755(MyD88-dependent toll-like receptor signaling pathway);GO:0002756(MyD88-independent toll-like receptor signaling pathway);GO:0007249(I-kappaB kinase/NF-kappaB signaling);GO:0034128(negative regulation of MyD88-independent toll-like receptor signaling pathway);GO:0034142(toll-like receptor 4 signaling pathway);GO:0035666(TRIF-dependent toll-like receptor signaling pathway);GO:0070266(necroptotic process);GO:0097190(apoptotic signaling pathway);GO:0046696(lipopolysaccharide receptor complex);GO:0007166(cell surface receptor signaling pathway);GO:0030667(secretory granule membrane);GO:0038123(toll-like receptor TLR1:TLR2 signaling pathway);GO:0038124(toll-like receptor TLR6:TLR2 signaling pathway);GO:0071223(cellular response to lipoteichoic acid);GO:0071726(cellular response to diacyl bacterial lipopeptide);GO:0071727(cellular response to triacyl bacterial lipopeptide);GO:0032760(positive regulation of tumor necrosis factor production);GO:0032729(positive regulation of interferon-gamma production);GO:0031362(anchored component of external side of plasma membrane);GO:0001530(lipopolysaccharide binding);GO:0001847(opsonin receptor activity);GO:0016019(peptidoglycan receptor activity);GO:0070891(lipoteichoic acid binding);GO:0071723(lipopeptide binding);GO:0002237(response to molecule of bacterial origin);GO:0006898(receptor-mediated endocytosis);GO:0006909(phagocytosis);GO:0009408(response to heat);GO:0009617(response to bacterium);GO:0031663(lipopolysaccharide-mediated signaling pathway);GO:0032026(response to magnesium ion);GO:0032481(positive regulation of type I interferon production);GO:0032496(response to lipopolysaccharide);GO:0034612(response to tumor necrosis factor);GO:0045471(response to ethanol);GO:0045807(positive regulation of endocytosis);GO:0050715(positive regulation of cytokine secretion);GO:0051602(response to electrical stimulus);GO:0071219(cellular response to molecule of bacterial origin);GO:1901224(positive regulation of NIK/NF-kappaB signaling);GO:2000484(positive regulation of interleukin-8 secretion);GO:0009897(external side of plasma membrane);GO:0009986(cell surface)","04010(MAPK signaling pathway);04064(NF-kappa B signaling pathway);04145(Phagosome);04810(Regulation of actin cytoskeleton);04640(Hematopoietic cell lineage);04620(Toll-like receptor signaling pathway);05202(Transcriptional misregulation in cancers);05221(Acute myeloid leukemia);05130(Pathogenic Escherichia coli infection);05132(Salmonella infection);05133(Pertussis);05134(Legionellosis);05152(Tuberculosis);05146(Amoebiasis)","K04391","NA","CD14 molecule [Source:HGNC Symbol;Acc:HGNC:1628]",{"v":3.032354,"d":"3.03"},{"v":27.293585,"d":"27.29"},{"v":0.111101344876461,"d":"0.11"},{"v":-3.17005181430026,"d":"-3.17"},{"v":2.79049114937614E-6,"d":"0.00"},{"v":2.44328490548031E-4,"d":"0.00"},"down","yes"]
[49264,0,"chr13","+",27251597,27256568,"ENST00000326092",6,641,"MSTRG.3921","RPL21","GO:0003723(RNA binding);GO:0016020(membrane);GO:0006412(translation);GO:0030529(intracellular ribonucleoprotein complex);GO:0005622(intracellular);GO:0003735(structural constituent of ribosome);GO:0005840(ribosome);GO:0005829(cytosol);GO:0005515(protein binding);GO:0006413(translational initiation);GO:0006364(rRNA processing);GO:0000184(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay);GO:0019083(viral transcription);GO:0006614(SRP-dependent cotranslational protein targeting to membrane);GO:0022625(cytosolic large ribosomal subunit)","03010(Ribosome)","NA","NA","ribosomal protein L21 [Source:HGNC Symbol;Acc:HGNC:10313]",{"v":17.751619,"d":"17.75"},{"v":157.735825,"d":"157.74"},{"v":0.11254018546516,"d":"0.11"},{"v":-3.15148784882953,"d":"-3.15"},{"v":2.90508092463661e-06,"d":"0.00"},{"v":0.000253241151263036,"d":"0.00"},"down","yes"]
[187278,0,"chr8","-",130052104,130180862,"ENST00000524124",24,5478,"MSTRG.14569","ASAP1","GO:0043547(positive regulation of GTPase activity);GO:0005096(GTPase activator activity);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0046872(metal ion binding);GO:0005515(protein binding);GO:0060271(cilium assembly);GO:0005829(cytosol);GO:0045296(cadherin binding);GO:0030030(cell projection organization);GO:0001786(phosphatidylserine binding);GO:0005546(phosphatidylinositol-4,5-bisphosphate binding);GO:0005547(phosphatidylinositol-3,4,5-trisphosphate binding);GO:0061000(negative regulation of dendritic spine development);GO:0071803(positive regulation of podosome assembly);GO:1903527(positive regulation of membrane tubulation);GO:0002102(podosome);GO:0031253(cell projection membrane);GO:0043197(dendritic spine)","04144(Endocytosis);04666(Fc gamma R-mediated phagocytosis)","K12488","NA","ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 [Source:HGNC Symbol;Acc:HGNC:2720]",{"v":0.362617,"d":"0.36"},{"v":3.302499,"d":"3.30"},{"v":0.10980079025005,"d":"0.11"},{"v":-3.18703965724985,"d":"-3.19"},{"v":3.07608391839219e-06,"d":"0.00"},{"v":0.000265763760898843,"d":"0.00"},"down","yes"]
[56577,0,"chr14","-",73275216,73458522,"ENST00000557597",12,3547,"MSTRG.4515","NUMB","GO:0016020(membrane);GO:0005515(protein binding);GO:0007275(multicellular organism development);GO:0007399(nervous system development);GO:0005925(focal adhesion);GO:0005886(plasma membrane);GO:0045296(cadherin binding);GO:0030335(positive regulation of cell migration);GO:0030136(clathrin-coated vesicle);GO:0050769(positive regulation of neurogenesis);GO:1903077(negative regulation of protein localization to plasma membrane);GO:0021670(lateral ventricle development);GO:0021849(neuroblast division in subventricular zone);GO:0008013(beta-catenin binding);GO:0045294(alpha-catenin binding);GO:0007405(neuroblast proliferation);GO:0007409(axonogenesis);GO:0030862(positive regulation of polarized epithelial cell differentiation);GO:0030900(forebrain development);GO:0034332(adherens junction organization);GO:0045746(negative regulation of Notch signaling pathway);GO:0060487(lung epithelial cell differentiation);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005769(early endosome);GO:0016323(basolateral plasma membrane);GO:0019897(extrinsic component of plasma membrane);GO:0031410(cytoplasmic vesicle);GO:0045177(apical part of cell)","04330(Notch signaling pathway)","K06057","NA","NUMB, endocytic adaptor protein [Source:HGNC Symbol;Acc:HGNC:8060]",{"v":6.880651,"d":"6.88"},{"v":0.574318,"d":"0.57"},{"v":11.9805595506322,"d":"11.98"},{"v":3.58262338549073,"d":"3.58"},{"v":3.07756876590104e-06,"d":"0.00"},{"v":0.000265763760898843,"d":"0.00"},"up","yes"]
[174142,0,"chr7","-",55470613,55572525,"ENST00000285279",5,2962,"MSTRG.13647","VOPP1","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0004871(signal transducer activity);GO:0030659(cytoplasmic vesicle membrane);GO:0031410(cytoplasmic vesicle);GO:0007165(signal transduction);GO:0031301(integral component of organelle membrane);GO:0005768(endosome)","NA","NA","NA","vesicular, overexpressed in cancer, prosurvival protein 1 [Source:HGNC Symbol;Acc:HGNC:34518]",{"v":3.170434,"d":"3.17"},{"v":27.98535,"d":"27.99"},{"v":0.113289060168981,"d":"0.11"},{"v":-3.14191954177813,"d":"-3.14"},{"v":3.08902693585678e-06,"d":"0.00"},{"v":0.000265763760898843,"d":"0.00"},"down","yes"]
[70192,0,"chr16","-",18781295,18790334,"ENST00000322989",5,2203,"MSTRG.5711","RPS15A","GO:0003723(RNA binding);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0006412(translation);GO:0030529(intracellular ribonucleoprotein complex);GO:0003735(structural constituent of ribosome);GO:0005840(ribosome);GO:0022627(cytosolic small ribosomal subunit);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0009615(response to virus);GO:0031012(extracellular matrix);GO:0005739(mitochondrion);GO:0005515(protein binding);GO:0008284(positive regulation of cell proliferation);GO:0006413(translational initiation);GO:0006364(rRNA processing);GO:0045787(positive regulation of cell cycle);GO:0000184(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay);GO:0019083(viral transcription);GO:0006614(SRP-dependent cotranslational protein targeting to membrane)","03010(Ribosome)","K02957","NA","ribosomal protein S15a [Source:HGNC Symbol;Acc:HGNC:10389]",{"v":13.749027,"d":"13.75"},{"v":119.784409,"d":"119.78"},{"v":0.114781440379273,"d":"0.11"},{"v":-3.12303871103955,"d":"-3.12"},{"v":3.30566385213665e-06,"d":"0.00"},{"v":0.000283170893099913,"d":"0.00"},"down","yes"]
[24397,0,"chr10","+",130136399,130179664,"ENST00000331244",11,1302,"MSTRG.2044","GLRX3","GO:0003723(RNA binding);GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0005829(cytosol);GO:0045454(cell redox homeostasis);GO:0055114(oxidation-reduction process);GO:0005515(protein binding);GO:0051536(iron-sulfur cluster binding);GO:0009055(electron carrier activity);GO:0015035(protein disulfide oxidoreductase activity);GO:0070062(extracellular exosome);GO:0005938(cell cortex);GO:0030018(Z disc);GO:0002026(regulation of the force of heart contraction);GO:0010614(negative regulation of cardiac muscle hypertrophy);GO:0044571([2Fe-2S] cluster assembly);GO:0097428(protein maturation by iron-sulfur cluster transfer);GO:0005080(protein kinase C binding);GO:0005634(nucleus);GO:0030425(dendrite)","NA","NA","NA","glutaredoxin 3 [Source:HGNC Symbol;Acc:HGNC:15987]",{"v":1.035936,"d":"1.04"},{"v":9.491426,"d":"9.49"},{"v":0.109144400430452,"d":"0.11"},{"v":-3.1956899790199,"d":"-3.20"},{"v":3.39482922950782e-06,"d":"0.00"},{"v":0.000289555520661641,"d":"0.00"},"down","yes"]
[87231,0,"chr17","+",67825664,67984378,"ENST00000321892",30,11292,"ENSG00000171634","BPTF","GO:0046872(metal ion binding);GO:0005654(nucleoplasm);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0016569(covalent chromatin modification);GO:0005515(protein binding);GO:0070062(extracellular exosome);GO:0000790(nuclear chromatin);GO:0045893(positive regulation of transcription, DNA-templated);GO:0048188(Set1C/COMPASS complex);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0016589(NURF complex);GO:0008134(transcription factor binding);GO:0043565(sequence-specific DNA binding);GO:0007420(brain development);GO:0008094(DNA-dependent ATPase activity);GO:0006338(chromatin remodeling);GO:0001892(embryonic placenta development);GO:0007492(endoderm development);GO:0009611(response to wounding);GO:0009952(anterior/posterior pattern specification);GO:1990090(cellular response to nerve growth factor stimulus);GO:0030425(dendrite);GO:0043005(neuron projection);GO:0044297(cell body);GO:0048471(perinuclear region of cytoplasm)","NA","NA","NA","bromodomain PHD finger transcription factor [Source:HGNC Symbol;Acc:HGNC:3581]",{"v":2.656539,"d":"2.66"},{"v":0.228323,"d":"0.23"},{"v":11.6350039198854,"d":"11.64"},{"v":3.54039979168119,"d":"3.54"},{"v":3.57778569819448e-06,"d":"0.00"},{"v":0.000303850744188293,"d":"0.00"},"up","yes"]
[163266,"j","chr6","-",24797373,24950536,"MSTRG.12716.2",25,5497,"MSTRG.12716","RIPOR2","NA","NA","NA","NA","NA",{"v":0.281958,"d":"0.28"},{"v":2.53054,"d":"2.53"},{"v":0.111422068017103,"d":"0.11"},{"v":-3.16589309680724,"d":"-3.17"},{"v":3.66027539733037e-06,"d":"0.00"},{"v":0.000309527904112706,"d":"0.00"},"down","yes"]
[103965,0,"chr19","-",49555711,49580572,"ENST00000596358",9,1005,"MSTRG.8321","NOSIP","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0050999(regulation of nitric-oxide synthase activity);GO:0003723(RNA binding);GO:0016740(transferase activity);GO:0007275(multicellular organism development);GO:0061630(ubiquitin protein ligase activity);GO:0005515(protein binding);GO:0005829(cytosol);GO:0016567(protein ubiquitination);GO:0000139(Golgi membrane);GO:0043086(negative regulation of catalytic activity);GO:0051001(negative regulation of nitric-oxide synthase activity);GO:0004842(ubiquitin-protein transferase activity)","NA","NA","NA","nitric oxide synthase interacting protein [Source:HGNC Symbol;Acc:HGNC:17946]",{"v":3.347943,"d":"3.35"},{"v":29.268984,"d":"29.27"},{"v":0.114385350718016,"d":"0.11"},{"v":-3.1280257962654,"d":"-3.13"},{"v":3.86778655555743e-06,"d":"0.00"},{"v":0.000325684086644129,"d":"0.00"},"down","yes"]
[124733,"j","chr20","-",53568920,53592754,"MSTRG.9839.5",6,4050,"MSTRG.9839","ZNF217","NA","NA","NA","NA","NA",{"v":13.970312,"d":"13.97"},{"v":1.22725,"d":"1.23"},{"v":11.3834279894072,"d":"11.38"},{"v":3.50886316910447,"d":"3.51"},{"v":4.03743282561554e-06,"d":"0.00"},{"v":0.000338528477768137,"d":"0.00"},"up","yes"]
[33214,0,"chr11","+",75399531,75422280,"ENST00000527446",7,1306,"MSTRG.2719","RPS3","GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0006412(translation);GO:0006413(translational initiation);GO:0005783(endoplasmic reticulum);GO:0005829(cytosol);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0005743(mitochondrial inner membrane);GO:0016829(lyase activity);GO:0003677(DNA binding);GO:0030529(intracellular ribonucleoprotein complex);GO:0003735(structural constituent of ribosome);GO:0005840(ribosome);GO:0051301(cell division);GO:0005739(mitochondrion);GO:0005886(plasma membrane);GO:0015935(small ribosomal subunit);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0006281(DNA repair);GO:0006974(cellular response to DNA damage stimulus);GO:0007049(cell cycle);GO:0006915(apoptotic process);GO:0022627(cytosolic small ribosomal subunit);GO:0005759(mitochondrial matrix);GO:0051536(iron-sulfur cluster binding);GO:0005730(nucleolus);GO:0005925(focal adhesion);GO:0008017(microtubule binding);GO:0005819(spindle);GO:0007059(chromosome segregation);GO:0003729(mRNA binding);GO:0003906(DNA-(apurinic or apyrimidinic site) lyase activity);GO:0005654(nucleoplasm);GO:0070062(extracellular exosome);GO:0019901(protein kinase binding);GO:0010628(positive regulation of gene expression);GO:0032587(ruffle membrane);GO:0006417(regulation of translation);GO:0031012(extracellular matrix);GO:0017148(negative regulation of translation);GO:0002181(cytoplasmic translation);GO:0042981(regulation of apoptotic process);GO:0019899(enzyme binding);GO:0008134(transcription factor binding);GO:0006979(response to oxidative stress);GO:0015631(tubulin binding);GO:0006364(rRNA processing);GO:0031397(negative regulation of protein ubiquitination);GO:0000184(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay);GO:0051225(spindle assembly);GO:0019083(viral transcription);GO:0045739(positive regulation of DNA repair);GO:0003684(damaged DNA binding);GO:0032357(oxidized purine DNA binding);GO:0019900(kinase binding);GO:0043507(positive regulation of JUN kinase activity);GO:0051018(protein kinase A binding);GO:1901224(positive regulation of NIK/NF-kappaB signaling);GO:0072686(mitotic spindle);GO:0051879(Hsp90 protein binding);GO:0097100(supercoiled DNA binding);GO:0006614(SRP-dependent cotranslational protein targeting to membrane);GO:0070301(cellular response to hydrogen peroxide);GO:0005844(polysome);GO:2001235(positive regulation of apoptotic signaling pathway);GO:0031334(positive regulation of protein complex assembly);GO:0031116(positive regulation of microtubule polymerization);GO:0000977(RNA polymerase II regulatory region sequence-specific DNA binding);GO:0004520(endodeoxyribonuclease activity);GO:0030544(Hsp70 protein binding);GO:0032358(oxidized pyrimidine DNA binding);GO:0032403(protein complex binding);GO:0044390(ubiquitin-like protein conjugating enzyme binding);GO:0070181(small ribosomal subunit rRNA binding);GO:0032079(positive regulation of endodeoxyribonuclease activity);GO:0032743(positive regulation of interleukin-2 production);GO:0042104(positive regulation of activated T cell proliferation);GO:0042769(DNA damage response, detection of DNA damage);GO:0045738(negative regulation of DNA repair);GO:0050862(positive regulation of T cell receptor signaling pathway);GO:0051092(positive regulation of NF-kappaB transcription factor activity);GO:0061481(response to TNF agonist);GO:0071356(cellular response to tumor necrosis factor);GO:1902231(positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage);GO:1902546(positive regulation of DNA N-glycosylase activity);GO:1905053(positive regulation of base-excision repair);GO:2001272(positive regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis);GO:0071159(NF-kappaB complex)","03010(Ribosome)","K02985","NA","ribosomal protein S3 [Source:HGNC Symbol;Acc:HGNC:10420]",{"v":3.52566,"d":"3.53"},{"v":30.17503,"d":"30.18"},{"v":0.116840314657517,"d":"0.12"},{"v":-3.09738994634379,"d":"-3.10"},{"v":4.30894817120307e-06,"d":"0.00"},{"v":0.000359769900471588,"d":"0.00"},"down","yes"]
[11810,0,"chr1","-",155659446,155688774,"ENST00000359205",10,2690,"MSTRG.1062","YY1AP1","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0001650(fibrillar center);GO:0005515(protein binding);GO:0030154(cell differentiation);GO:0005654(nucleoplasm);GO:0005730(nucleolus);GO:0008283(cell proliferation);GO:0051726(regulation of cell cycle);GO:0031011(Ino80 complex)","NA","NA","NA","YY1 associated protein 1 [Source:HGNC Symbol;Acc:HGNC:30935]",{"v":0.379847,"d":"0.38"},{"v":3.414655,"d":"3.41"},{"v":0.111240227782895,"d":"0.11"},{"v":-3.16824949092871,"d":"-3.17"},{"v":4.37824739289418e-06,"d":"0.00"},{"v":3.64019997523488E-4,"d":"0.00"},"down","yes"]
[145964,0,"chr4","-",10074339,10116860,"ENST00000499869",15,3054,"MSTRG.11535","WDR1","GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0003779(actin binding);GO:0005856(cytoskeleton);GO:0042995(cell projection);GO:0030054(cell junction);GO:0005576(extracellular region);GO:0051015(actin filament binding);GO:0070062(extracellular exosome);GO:0002102(podosome);GO:0045214(sarcomere organization);GO:0030864(cortical actin cytoskeleton);GO:0002576(platelet degranulation);GO:0005911(cell-cell junction);GO:0007605(sensory perception of sound);GO:0002446(neutrophil mediated immunity);GO:0008360(regulation of cell shape);GO:0030036(actin cytoskeleton organization);GO:0030043(actin filament fragmentation);GO:0030220(platelet formation);GO:0030834(regulation of actin filament depolymerization);GO:0030836(positive regulation of actin filament depolymerization);GO:0030865(cortical cytoskeleton organization);GO:0040011(locomotion);GO:0042247(establishment of planar polarity of follicular epithelium);GO:0043297(apical junction assembly);GO:0045199(maintenance of epithelial cell apical/basal polarity);GO:0048713(regulation of oligodendrocyte differentiation);GO:0060307(regulation of ventricular cardiac muscle cell membrane repolarization);GO:1990266(neutrophil migration);GO:0005884(actin filament);GO:0042643(actomyosin, actin portion);GO:0043209(myelin sheath)","NA","NA","NA","WD repeat domain 1 [Source:HGNC Symbol;Acc:HGNC:12754]",{"v":9.048819,"d":"9.05"},{"v":0.792844,"d":"0.79"},{"v":11.413114055224,"d":"11.41"},{"v":3.51262057793097,"d":"3.51"},{"v":4.43304609959244e-06,"d":"0.00"},{"v":0.000366869318110783,"d":"0.00"},"up","yes"]
[53294,0,"chr14","-",23559612,23567324,"ENST00000465445",18,2554,"MSTRG.4277","AP1G2","GO:0006810(transport);GO:0016020(membrane);GO:0008565(protein transporter activity);GO:0006886(intracellular protein transport);GO:0015031(protein transport);GO:0016192(vesicle-mediated transport);GO:0030117(membrane coat);GO:0005794(Golgi apparatus);GO:0030131(clathrin adaptor complex);GO:0005515(protein binding);GO:0000139(Golgi membrane);GO:0030659(cytoplasmic vesicle membrane);GO:0031410(cytoplasmic vesicle);GO:0005768(endosome);GO:0010008(endosome membrane);GO:0016032(viral process);GO:0030133(transport vesicle);GO:0005798(Golgi-associated vesicle);GO:0030121(AP-1 adaptor complex)","04142(Lysosome)","K12391","NA","adaptor related protein complex 1 gamma 2 subunit [Source:HGNC Symbol;Acc:HGNC:556]",{"v":0.342595,"d":"0.34"},{"v":3.133246,"d":"3.13"},{"v":0.109341877401264,"d":"0.11"},{"v":-3.1930820429345,"d":"-3.19"},{"v":4.44959755137396e-06,"d":"0.00"},{"v":0.000366869318110783,"d":"0.00"},"down","yes"]
[116290,0,"chr2","-",170992154,171160495,"ENST00000359766",23,4321,"MSTRG.9228","TLK1","GO:0005634(nucleus);GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0016569(covalent chromatin modification);GO:0005515(protein binding);GO:0006974(cellular response to DNA damage stimulus);GO:0007049(cell cycle);GO:0006886(intracellular protein transport);GO:0035556(intracellular signal transduction);GO:0001672(regulation of chromatin assembly or disassembly)","NA","NA","NA","tousled like kinase 1 [Source:HGNC Symbol;Acc:HGNC:11841]",{"v":4.696242,"d":"4.70"},{"v":0.410281,"d":"0.41"},{"v":11.4464038061719,"d":"11.45"},{"v":3.51682250317253,"d":"3.52"},{"v":4.66301108552719e-06,"d":"0.00"},{"v":0.000382869972449843,"d":"0.00"},"up","yes"]
[29692,0,"chr11","+",60378485,60395951,"ENST00000358246",6,2871,"ENSG00000166927","MS4A7","GO:0016020(membrane);GO:0016021(integral component of membrane)","NA","NA","NA","membrane spanning 4-domains A7 [Source:HGNC Symbol;Acc:HGNC:13378]",{"v":0.399078,"d":"0.40"},{"v":3.529426,"d":"3.53"},{"v":0.113071643944369,"d":"0.11"},{"v":-3.14469091861,"d":"-3.14"},{"v":4.7808317862152e-06,"d":"0.00"},{"v":0.000390921898287712,"d":"0.00"},"down","yes"]
[28783,0,"chr11","+",47269684,47329357,"ENST00000395344",33,4988,"ENSG00000110514","MADD","GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0043547(positive regulation of GTPase activity);GO:0005515(protein binding);GO:0006915(apoptotic process);GO:0005085(guanyl-nucleotide exchange factor activity);GO:0017112(Rab guanyl-nucleotide exchange factor activity);GO:0061024(membrane organization);GO:0042981(regulation of apoptotic process);GO:0007166(cell surface receptor signaling pathway);GO:0051726(regulation of cell cycle);GO:0010803(regulation of tumor necrosis factor-mediated signaling pathway);GO:0000187(activation of MAPK activity);GO:0097194(execution phase of apoptosis);GO:0032483(regulation of Rab protein signal transduction);GO:0030295(protein kinase activator activity);GO:1902041(regulation of extrinsic apoptotic signaling pathway via death domain receptors);GO:0005123(death receptor binding);GO:2001236(regulation of extrinsic apoptotic signaling pathway)","NA","NA","NA","MAP kinase activating death domain [Source:HGNC Symbol;Acc:HGNC:6766]",{"v":1.936514,"d":"1.94"},{"v":0.16642,"d":"0.17"},{"v":11.6363057324841,"d":"11.64"},{"v":3.54056120232891,"d":"3.54"},{"v":5.25456203533615e-06,"d":"0.00"},{"v":4.26977711252651E-4,"d":"0.00"},"up","yes"]
[192670,0,"chr9","-",112218435,112333667,"ENST00000374257",14,7240,"MSTRG.14903","PTBP3","GO:0005634(nucleus);GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0006397(mRNA processing);GO:0008380(RNA splicing);GO:0045595(regulation of cell differentiation);GO:0030154(cell differentiation);GO:0043249(erythrocyte maturation);GO:0009653(anatomical structure morphogenesis);GO:0033119(negative regulation of RNA splicing)","NA","NA","NA","polypyrimidine tract binding protein 3 [Source:HGNC Symbol;Acc:HGNC:10253]",{"v":14.685103,"d":"14.69"},{"v":1.344158,"d":"1.34"},{"v":10.9251315693542,"d":"10.93"},{"v":3.44957874882943,"d":"3.45"},{"v":5.26493640315579e-06,"d":"0.00"},{"v":4.26977711252651E-4,"d":"0.00"},"up","yes"]
[30123,0,"chr11","-",61964566,61967631,"ENST00000620041",5,825,"MSTRG.2449","FTH1","GO:0005623(cell);GO:0008199(ferric iron binding);GO:0006826(iron ion transport);GO:0006879(cellular iron ion homeostasis);GO:0046872(metal ion binding);GO:0005634(nucleus);GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0005515(protein binding);GO:0006955(immune response);GO:0005576(extracellular region);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0008285(negative regulation of cell proliferation);GO:0043312(neutrophil degranulation);GO:1904813(ficolin-1-rich granule lumen);GO:1904724(tertiary granule lumen);GO:0004322(ferroxidase activity);GO:0048147(negative regulation of fibroblast proliferation);GO:0005506(iron ion binding);GO:0008043(intracellular ferritin complex);GO:0044754(autolysosome);GO:0006880(intracellular sequestering of iron ion);GO:0016020(membrane);GO:0016021(integral component of membrane)","04216(Ferroptosis);04217(Necroptosis);04978(Mineral absorption)","NA","NA","ferritin heavy chain 1 [Source:HGNC Symbol;Acc:HGNC:3976]",{"v":29.46842,"d":"29.47"},{"v":242.442474,"d":"242.44"},{"v":0.121548091445396,"d":"0.12"},{"v":-3.04040085461722,"d":"-3.04"},{"v":5.32276856006135e-06,"d":"0.00"},{"v":0.000429905894965282,"d":"0.00"},"down","yes"]
[182688,0,"chr8","-",30063098,30083124,"ENST00000518174",6,1981,"MSTRG.14272","SARAF","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0006811(ion transport);GO:0006816(calcium ion transport);GO:0030176(integral component of endoplasmic reticulum membrane);GO:0005515(protein binding);GO:2001256(regulation of store-operated calcium entry)","NA","NA","NA","store-operated calcium entry associated regulatory factor [Source:HGNC Symbol;Acc:HGNC:28789]",{"v":2.504307,"d":"2.50"},{"v":20.818092,"d":"20.82"},{"v":0.120294741708318,"d":"0.12"},{"v":-3.05535451369617,"d":"-3.06"},{"v":5.46432082429621e-06,"d":"0.00"},{"v":0.000439544636061681,"d":"0.00"},"down","yes"]
[103550,0,"chr19","-",48615328,48619536,"ENST00000549920",7,1004,"MSTRG.8290","RPL18","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0006412(translation);GO:0005783(endoplasmic reticulum);GO:0005730(nucleolus);GO:0005829(cytosol);GO:0030529(intracellular ribonucleoprotein complex);GO:0005622(intracellular);GO:0003735(structural constituent of ribosome);GO:0005840(ribosome);GO:0005925(focal adhesion);GO:0006413(translational initiation);GO:0003723(RNA binding);GO:0006364(rRNA processing);GO:0000184(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay);GO:0019083(viral transcription);GO:0006614(SRP-dependent cotranslational protein targeting to membrane);GO:0022625(cytosolic large ribosomal subunit)","03010(Ribosome)","K02883","NA","ribosomal protein L18 [Source:HGNC Symbol;Acc:HGNC:10310]",{"v":32.997322,"d":"33.00"},{"v":269.865021,"d":"269.87"},{"v":0.122273430909002,"d":"0.12"},{"v":-3.03181714367987,"d":"-3.03"},{"v":5.58063320866139e-06,"d":"0.00"},{"v":0.000447083279080938,"d":"0.00"},"down","yes"]
[42901,0,"chr12","+",56116632,56117710,"ENST00000546485",4,335,"MSTRG.3447","RPL41","GO:0006412(translation);GO:0030529(intracellular ribonucleoprotein complex);GO:0003735(structural constituent of ribosome);GO:0005840(ribosome);GO:0005829(cytosol);GO:0006413(translational initiation);GO:0003723(RNA binding);GO:0006364(rRNA processing);GO:0000184(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay);GO:0019083(viral transcription);GO:0003730(mRNA 3'-UTR binding);GO:0048027(mRNA 5'-UTR binding);GO:0006614(SRP-dependent cotranslational protein targeting to membrane);GO:0022625(cytosolic large ribosomal subunit)","03010(Ribosome)","NA","NA","ribosomal protein L41 [Source:HGNC Symbol;Acc:HGNC:10354]",{"v":2.735838,"d":"2.74"},{"v":24.194572,"d":"24.19"},{"v":0.113076519807831,"d":"0.11"},{"v":-3.14462870820845,"d":"-3.14"},{"v":5.72609087616906e-06,"d":"0.00"},{"v":0.000454687429518278,"d":"0.00"},"down","yes"]
[30672,0,"chr11","+",64230278,64234281,"ENST00000321685",7,1288,"MSTRG.2511","DNAJC4","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005515(protein binding);GO:0006457(protein folding);GO:0051082(unfolded protein binding);GO:0006986(response to unfolded protein);GO:0005739(mitochondrion)","NA","NA","NA","DnaJ heat shock protein family (Hsp40) member C4 [Source:HGNC Symbol;Acc:HGNC:5271]",{"v":1.019898,"d":"1.02"},{"v":8.740685,"d":"8.74"},{"v":0.116683989870359,"d":"0.12"},{"v":-3.09932147145287,"d":"-3.10"},{"v":5.7291631487822e-06,"d":"0.00"},{"v":0.000454687429518278,"d":"0.00"},"down","yes"]
[16531,0,"chr1","+",226061851,226071523,"ENST00000366816",5,799,"MSTRG.1426","H3F3A","GO:0005634(nucleus);GO:0003677(DNA binding);GO:0046982(protein heterodimerization activity);GO:0006334(nucleosome assembly);GO:0000786(nucleosome);GO:0005694(chromosome);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0005654(nucleoplasm);GO:0070062(extracellular exosome);GO:0044267(cellular protein metabolic process);GO:1902036(regulation of hematopoietic stem cell differentiation);GO:0043234(protein complex);GO:0000784(nuclear chromosome, telomeric region);GO:0045815(positive regulation of gene expression, epigenetic);GO:0042393(histone binding);GO:0030307(positive regulation of cell growth);GO:0045652(regulation of megakaryocyte differentiation);GO:0006336(DNA replication-independent nucleosome assembly);GO:0007596(blood coagulation);GO:0000228(nuclear chromosome);GO:0060964(regulation of gene silencing by miRNA);GO:0000183(chromatin silencing at rDNA);GO:0045814(negative regulation of gene expression, epigenetic);GO:0000979(RNA polymerase II core promoter sequence-specific DNA binding);GO:0031492(nucleosomal DNA binding);GO:0000980(RNA polymerase II distal enhancer sequence-specific DNA binding);GO:0000788(nuclear nucleosome);GO:0032200(telomere organization);GO:0001649(osteoblast differentiation);GO:0006997(nucleus organization);GO:0007283(spermatogenesis);GO:0007286(spermatid development);GO:0007338(single fertilization);GO:0007420(brain development);GO:0007566(embryo implantation);GO:0008283(cell proliferation);GO:0008584(male gonad development);GO:0009725(response to hormone);GO:0031508(pericentric heterochromatin assembly);GO:0031509(telomeric heterochromatin assembly);GO:0035264(multicellular organism growth);GO:0042692(muscle cell differentiation);GO:0048477(oogenesis);GO:0090230(regulation of centromere complex assembly);GO:1902340(negative regulation of chromosome condensation);GO:0001740(Barr body)","05202(Transcriptional misregulation in cancers);05322(Systemic lupus erythematosus);05034(Alcoholism)","NA","NA","H3 histone family member 3A [Source:HGNC Symbol;Acc:HGNC:4764]",{"v":109.451317,"d":"109.45"},{"v":10.096448,"d":"10.10"},{"v":10.8405765076985,"d":"10.84"},{"v":3.43836957691877,"d":"3.44"},{"v":5.75534561710319e-06,"d":"0.00"},{"v":0.000454687429518278,"d":"0.00"},"up","yes"]
[164493,0,"chr6","+",31620725,31637771,"ENST00000376033",31,6893,"MSTRG.12866","PRRC2A","GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005515(protein binding);GO:0070062(extracellular exosome);GO:0030154(cell differentiation)","NA","NA","NA","proline rich coiled-coil 2A [Source:HGNC Symbol;Acc:HGNC:13918]",{"v":10.489512,"d":"10.49"},{"v":0.966629,"d":"0.97"},{"v":10.8516421501941,"d":"10.85"},{"v":3.43984147328762,"d":"3.44"},{"v":5.76746234127187e-06,"d":"0.00"},{"v":0.000454687429518278,"d":"0.00"},"up","yes"]
[164148,"j","chr6","-",30727866,30742706,"MSTRG.12830.3",12,2008,"MSTRG.12830","FLOT1","NA","NA","NA","NA","NA",{"v":3.734538,"d":"3.73"},{"v":30.618156,"d":"30.62"},{"v":0.121971355819077,"d":"0.12"},{"v":-3.03538571488462,"d":"-3.04"},{"v":5.84109662204527e-06,"d":"0.00"},{"v":0.00045866515855965,"d":"0.00"},"down","yes"]
[126727,0,"chr21","+",33543065,33559056,"ENST00000381679",5,7860,"MSTRG.10037","SON","GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0006397(mRNA processing);GO:0008380(RNA splicing);GO:0005634(nucleus);GO:0016607(nuclear speck);GO:0003677(DNA binding);GO:0007049(cell cycle);GO:0043484(regulation of RNA splicing);GO:0051726(regulation of cell cycle);GO:0005515(protein binding);GO:0043066(negative regulation of apoptotic process);GO:0000226(microtubule cytoskeleton organization);GO:0000281(mitotic cytokinesis);GO:0048024(regulation of mRNA splicing, via spliceosome);GO:0050733(RS domain binding)","NA","NA","NA","SON DNA binding protein [Source:HGNC Symbol;Acc:HGNC:11183]",{"v":6.084679,"d":"6.08"},{"v":0.564537,"d":"0.56"},{"v":10.7781757440168,"d":"10.78"},{"v":3.43004111084664,"d":"3.43"},{"v":6.32770289608816e-06,"d":"0.00"},{"v":0.000493643342311167,"d":"0.00"},"up","yes"]
[121834,0,"chr20","-",5544439,5586037,"ENST00000481038",15,6649,"MSTRG.9589","GPCPD1","GO:0005737(cytoplasm);GO:0030246(carbohydrate binding);GO:0016787(hydrolase activity);GO:0006629(lipid metabolic process);GO:0005829(cytosol);GO:0008081(phosphoric diester hydrolase activity);GO:0047389(glycerophosphocholine phosphodiesterase activity);GO:0046475(glycerophospholipid catabolic process);GO:2001070(starch binding);GO:0030643(cellular phosphate ion homeostasis);GO:0008889(glycerophosphodiester phosphodiesterase activity);GO:0007519(skeletal muscle tissue development)","00564(Glycerophospholipid metabolism);05231(Choline metabolism in cancer)","NA","NA","glycerophosphocholine phosphodiesterase 1 [Source:HGNC Symbol;Acc:HGNC:26957]",{"v":4.268749,"d":"4.27"},{"v":0.393099,"d":"0.39"},{"v":10.8592212139944,"d":"10.86"},{"v":3.44084873661198,"d":"3.44"},{"v":6.33643667611868E-6,"d":"0.00"},{"v":0.000493643342311167,"d":"0.00"},"up","yes"]
[184789,0,"chr8","+",73991352,74029087,"ENST00000284818",5,607,"MSTRG.14407","LY96","GO:0005515(protein binding);GO:0005576(extracellular region);GO:0005615(extracellular space);GO:0002376(immune system process);GO:0045087(innate immune response);GO:0006954(inflammatory response);GO:0005886(plasma membrane);GO:0010008(endosome membrane);GO:0001875(lipopolysaccharide receptor activity);GO:0002224(toll-like receptor signaling pathway);GO:0002755(MyD88-dependent toll-like receptor signaling pathway);GO:0002756(MyD88-independent toll-like receptor signaling pathway);GO:0007249(I-kappaB kinase/NF-kappaB signaling);GO:0032496(response to lipopolysaccharide);GO:0032497(detection of lipopolysaccharide);GO:0034128(negative regulation of MyD88-independent toll-like receptor signaling pathway);GO:0034142(toll-like receptor 4 signaling pathway);GO:0035666(TRIF-dependent toll-like receptor signaling pathway);GO:0070266(necroptotic process);GO:0097190(apoptotic signaling pathway);GO:0031226(intrinsic component of plasma membrane);GO:0046696(lipopolysaccharide receptor complex);GO:0007166(cell surface receptor signaling pathway);GO:0015026(coreceptor activity);GO:0006968(cellular defense response);GO:0032760(positive regulation of tumor necrosis factor production);GO:0031663(lipopolysaccharide-mediated signaling pathway);GO:0031666(positive regulation of lipopolysaccharide-mediated signaling pathway);GO:0071222(cellular response to lipopolysaccharide)","04064(NF-kappa B signaling pathway);04620(Toll-like receptor signaling pathway);05130(Pathogenic Escherichia coli infection);05133(Pertussis);05145(Toxoplasmosis)","K05400","NA","lymphocyte antigen 96 [Source:HGNC Symbol;Acc:HGNC:17156]",{"v":4.249609,"d":"4.25"},{"v":35.111015,"d":"35.11"},{"v":0.121033499031572,"d":"0.12"},{"v":-3.04652169037927,"d":"-3.05"},{"v":6.44896983585897e-06,"d":"0.00"},{"v":0.000500440059262656,"d":"0.00"},"down","yes"]
[21321,0,"chr10","+",73785624,73801797,"ENST00000398706",26,6062,"MSTRG.1812","ZSWIM8","GO:0008270(zinc ion binding);GO:0046872(metal ion binding)","NA","NA","NA","zinc finger SWIM-type containing 8 [Source:HGNC Symbol;Acc:HGNC:23528]",{"v":3.34431,"d":"3.34"},{"v":0.304772,"d":"0.30"},{"v":10.9731537017836,"d":"10.97"},{"v":3.45590631306665,"d":"3.46"},{"v":6.47482524206998e-06,"d":"0.00"},{"v":0.000500483757383128,"d":"0.00"},"up","yes"]
[199916,0,"chrX","-",130064874,130110716,"ENST00000335997",9,4145,"MSTRG.15437","ELF4","GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0006355(regulation of transcription, DNA-templated);GO:0006366(transcription from RNA polymerase II promoter);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0000981(RNA polymerase II transcription factor activity, sequence-specific DNA binding);GO:0043565(sequence-specific DNA binding);GO:0016604(nuclear body);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0045893(positive regulation of transcription, DNA-templated);GO:0045087(innate immune response);GO:0001787(natural killer cell proliferation);GO:0001866(NK T cell proliferation);GO:0005515(protein binding);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:0030154(cell differentiation);GO:0016605(PML body);GO:0001077(transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding)","NA","NA","NA","E74 like ETS transcription factor 4 [Source:HGNC Symbol;Acc:HGNC:3319]",{"v":3.947395,"d":"3.95"},{"v":0.359372,"d":"0.36"},{"v":10.9841473459257,"d":"10.98"},{"v":3.45735097852675,"d":"3.46"},{"v":6.72535026464353e-06,"d":"0.00"},{"v":0.00051782580169948,"d":"0.00"},"up","yes"]
[170566,0,"chr6","-",159682139,159693241,"ENST00000444946",4,917,"MSTRG.13403","SOD2","GO:0046872(metal ion binding);GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0004784(superoxide dismutase activity);GO:0006801(superoxide metabolic process);GO:0003677(DNA binding);GO:0019825(oxygen binding);GO:0019899(enzyme binding);GO:0030145(manganese ion binding);GO:0042802(identical protein binding);GO:0000302(response to reactive oxygen species);GO:0000303(response to superoxide);GO:0001306(age-dependent response to oxidative stress);GO:0001666(response to hypoxia);GO:0001836(release of cytochrome c from mitochondria);GO:0001889(liver development);GO:0003032(detection of oxygen);GO:0003069(acetylcholine-mediated vasodilation involved in regulation of systemic arterial blood pressure);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0006749(glutathione metabolic process);GO:0006979(response to oxidative stress);GO:0007005(mitochondrion organization);GO:0007507(heart development);GO:0007568(aging);GO:0007626(locomotory behavior);GO:0008217(regulation of blood pressure);GO:0008630(intrinsic apoptotic signaling pathway in response to DNA damage);GO:0008631(intrinsic apoptotic signaling pathway in response to oxidative stress);GO:0008637(apoptotic mitochondrial changes);GO:0009314(response to radiation);GO:0009409(response to cold);GO:0009791(post-embryonic development);GO:0010042(response to manganese ion);GO:0010043(response to zinc ion);GO:0010269(response to selenium ion);GO:0010332(response to gamma radiation);GO:0014823(response to activity);GO:0019430(removal of superoxide radicals);GO:0022904(respiratory electron transport chain);GO:0030097(hemopoiesis);GO:0031667(response to nutrient levels);GO:0032496(response to lipopolysaccharide);GO:0033591(response to L-ascorbic acid);GO:0034021(response to silicon dioxide);GO:0035900(response to isolation stress);GO:0035902(response to immobilization stress);GO:0042311(vasodilation);GO:0042493(response to drug);GO:0042542(response to hydrogen peroxide);GO:0042554(superoxide anion generation);GO:0042743(hydrogen peroxide metabolic process);GO:0043066(negative regulation of apoptotic process);GO:0045429(positive regulation of nitric oxide biosynthetic process);GO:0045599(negative regulation of fat cell differentiation);GO:0046686(response to cadmium ion);GO:0048147(negative regulation of fibroblast proliferation);GO:0048666(neuron development);GO:0048678(response to axon injury);GO:0048773(erythrophore differentiation);GO:0050665(hydrogen peroxide biosynthetic process);GO:0050790(regulation of catalytic activity);GO:0051260(protein homooligomerization);GO:0051602(response to electrical stimulus);GO:0051881(regulation of mitochondrial membrane potential);GO:0055072(iron ion homeostasis);GO:0055093(response to hyperoxia);GO:0071000(response to magnetism);GO:0071361(cellular response to ethanol);GO:0005737(cytoplasm);GO:0005739(mitochondrion);GO:0005743(mitochondrial inner membrane);GO:0042645(mitochondrial nucleoid);GO:0043209(myelin sheath);GO:0008285(negative regulation of cell proliferation);GO:0030335(positive regulation of cell migration);GO:0005759(mitochondrial matrix);GO:0070062(extracellular exosome);GO:0035722(interleukin-12-mediated signaling pathway);GO:0051289(protein homotetramerization);GO:0034599(cellular response to oxidative stress);GO:0043524(negative regulation of neuron apoptotic process);GO:1902176(negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway);GO:0001315(age-dependent response to reactive oxygen species);GO:0032364(oxygen homeostasis)","04068(FoxO signaling pathway);04146(Peroxisome);04211(Longevity regulating pathway - mammal);04213(Longevity regulating pathway - multiple species);05016(Huntington's disease)","K04564","EC:1.15.1.1","superoxide dismutase 2 [Source:HGNC Symbol;Acc:HGNC:11180]",{"v":24.476137,"d":"24.48"},{"v":2.247489,"d":"2.25"},{"v":10.890436838623,"d":"10.89"},{"v":3.44498991967451,"d":"3.44"},{"v":6.7720705449088e-06,"d":"0.00"},{"v":0.000519402061793238,"d":"0.00"},"up","yes"]
[40661,0,"chr12","-",46183063,46269012,"ENST00000398637",17,8066,"MSTRG.3311","SLC38A1","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0015293(symporter activity);GO:0006811(ion transport);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0006814(sodium ion transport);GO:0005887(integral component of plasma membrane);GO:0070062(extracellular exosome);GO:1902475(L-alpha-amino acid transmembrane transport);GO:0015171(amino acid transmembrane transporter activity);GO:0003333(amino acid transmembrane transport);GO:0006865(amino acid transport);GO:0015175(neutral amino acid transmembrane transporter activity);GO:0015804(neutral amino acid transport);GO:0015807(L-amino acid transport);GO:0001504(neurotransmitter uptake);GO:0005283(sodium:amino acid symporter activity);GO:0015179(L-amino acid transmembrane transporter activity);GO:0015186(L-glutamine transmembrane transporter activity);GO:0006868(glutamine transport);GO:0007565(female pregnancy);GO:0030424(axon)","04724(Glutamatergic synapse);04727(GABAergic synapse)","K14990","NA","solute carrier family 38 member 1 [Source:HGNC Symbol;Acc:HGNC:13447]",{"v":7.351644,"d":"7.35"},{"v":0.691115,"d":"0.69"},{"v":10.6373671530787,"d":"10.64"},{"v":3.41106920952092,"d":"3.41"},{"v":6.94615741733853e-06,"d":"0.00"},{"v":0.000530697154340907,"d":"0.00"},"up","yes"]
[173987,0,"chr7","+",50304782,50402525,"ENST00000359197",7,3487,"MSTRG.13644","IKZF1","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0043231(intracellular membrane-bounded organelle);GO:0046872(metal ion binding);GO:0005730(nucleolus);GO:0005654(nucleoplasm);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0016569(covalent chromatin modification);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0007049(cell cycle);GO:0030218(erythrocyte differentiation);GO:0007275(multicellular organism development);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0043234(protein complex);GO:0045892(negative regulation of transcription, DNA-templated);GO:0019904(protein domain specific binding);GO:0007498(mesoderm development);GO:0044212(transcription regulatory region DNA binding);GO:0031618(nuclear pericentric heterochromatin);GO:0030098(lymphocyte differentiation);GO:0051291(protein heterooligomerization)","NA","NA","NA","IKAROS family zinc finger 1 [Source:HGNC Symbol;Acc:HGNC:13176]",{"v":5.470034,"d":"5.47"},{"v":0.501533,"d":"0.50"},{"v":10.9066282777006,"d":"10.91"},{"v":3.44713326448115,"d":"3.45"},{"v":7.0040141444181e-06,"d":"0.00"},{"v":0.000533059353422098,"d":"0.00"},"up","yes"]
[124519,0,"chr20","+",49278642,49289260,"ENST00000428008",5,566,"MSTRG.9812","ZFAS1","NA","NA","NA","NA","ZNFX1 antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:33101]",{"v":2.692927,"d":"2.69"},{"v":22.264645,"d":"22.26"},{"v":0.120950816866831,"d":"0.12"},{"v":-3.04750758199163,"d":"-3.05"},{"v":7.13247026390163e-06,"d":"0.00"},{"v":0.000540756021387301,"d":"0.00"},"down","yes"]
[187965,0,"chr8","-",143574787,143578339,"ENST00000340490",12,1774,"MSTRG.14619","NAPRT","GO:0009435(NAD biosynthetic process);GO:0004514(nicotinate-nucleotide diphosphorylase (carboxylating) activity);GO:0016740(transferase activity);GO:0016757(transferase activity, transferring glycosyl groups);GO:0004516(nicotinate phosphoribosyltransferase activity);GO:0019358(nicotinate nucleotide salvage);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0016874(ligase activity);GO:0005515(protein binding);GO:0019363(pyridine nucleotide biosynthetic process);GO:0005576(extracellular region);GO:0070062(extracellular exosome);GO:0043312(neutrophil degranulation);GO:0006979(response to oxidative stress);GO:0035578(azurophil granule lumen);GO:0034356(NAD biosynthesis via nicotinamide riboside salvage pathway)","00760(Nicotinate and nicotinamide metabolism)","NA","NA","nicotinate phosphoribosyltransferase [Source:HGNC Symbol;Acc:HGNC:30450]",{"v":4.812756,"d":"4.81"},{"v":0.426679,"d":"0.43"},{"v":11.2795708249058,"d":"11.28"},{"v":3.49564027073052,"d":"3.50"},{"v":7.19938152542856e-06,"d":"0.00"},{"v":0.00054374565505794,"d":"0.00"},"up","yes"]
[128047,0,"chr21","-",46235133,46268062,"ENST00000486937",18,4593,"MSTRG.10092","MCM3AP","GO:0003676(nucleic acid binding);GO:0006810(transport);GO:0051028(mRNA transport);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0015031(protein transport);GO:0005829(cytosol);GO:0016740(transferase activity);GO:0031965(nuclear membrane);GO:0016746(transferase activity, transferring acyl groups);GO:0005643(nuclear pore);GO:0005654(nucleoplasm);GO:0002376(immune system process);GO:0003677(DNA binding);GO:0005635(nuclear envelope);GO:0006606(protein import into nucleus)","NA","NA","NA","minichromosome maintenance complex component 3 associated protein [Source:HGNC Symbol;Acc:HGNC:6946]",{"v":1.937516,"d":"1.94"},{"v":0.17277,"d":"0.17"},{"v":11.2144238004283,"d":"11.21"},{"v":3.48728359122595,"d":"3.49"},{"v":7.32030093339839E-6,"d":"0.00"},{"v":0.000550776102167632,"d":"0.00"},"up","yes"]
[104972,0,"chr19","-",52612378,52618040,"ENST00000541777",2,3743,"ENSG00000167766","ZNF83","GO:0003676(nucleic acid binding);GO:0006355(regulation of transcription, DNA-templated);GO:0005622(intracellular);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0005515(protein binding)","NA","NA","NA","zinc finger protein 83 [Source:HGNC Symbol;Acc:HGNC:13158]",{"v":0.237331,"d":"0.24"},{"v":2.031745,"d":"2.03"},{"v":0.116811410880795,"d":"0.12"},{"v":-3.09774688216745,"d":"-3.10"},{"v":7.69842603619789e-06,"d":"0.00"},{"v":0.000577032024258651,"d":"0.00"},"down","yes"]
[88537,"j","chr17","-",76734293,76737367,"MSTRG.7260.7",3,2463,"MSTRG.7260","SRSF2","NA","NA","NA","NA","NA",{"v":1.29448,"d":"1.29"},{"v":10.393373,"d":"10.39"},{"v":0.12454859457079,"d":"0.12"},{"v":-3.0052193528525,"d":"-3.01"},{"v":7.82412454475809e-06,"d":"0.00"},{"v":5.82135925876269E-4,"d":"0.00"},"down","yes"]
[120500,0,"chr2","-",234493041,234497053,"ENST00000390645",1,4013,"MSTRG.9507","ARL4C","GO:0006810(transport);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005525(GTP binding);GO:0007264(small GTPase mediated signal transduction);GO:0000166(nucleotide binding);GO:0005829(cytosol);GO:0005622(intracellular);GO:0005886(plasma membrane);GO:0042995(cell projection);GO:0005515(protein binding);GO:0030175(filopodium);GO:0043014(alpha-tubulin binding);GO:0005634(nucleus);GO:0003924(GTPase activity);GO:0032456(endocytic recycling)","NA","NA","NA","ADP ribosylation factor like GTPase 4C [Source:HGNC Symbol;Acc:HGNC:698]",{"v":2.174232,"d":"2.17"},{"v":17.190393,"d":"17.19"},{"v":0.1264794818827,"d":"0.13"},{"v":-2.9830247319993,"d":"-2.98"},{"v":7.82535659405132e-06,"d":"0.00"},{"v":5.82135925876269E-4,"d":"0.00"},"down","yes"]
[96972,0,"chr19","+",12163064,12189881,"ENST00000343979",4,3643,"ENSG00000196646","ZNF136","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0005622(intracellular);GO:0005515(protein binding);GO:0003714(transcription corepressor activity);GO:0006366(transcription from RNA polymerase II promoter);GO:0000122(negative regulation of transcription from RNA polymerase II promoter)","NA","NA","NA","zinc finger protein 136 [Source:HGNC Symbol;Acc:HGNC:12920]",{"v":0.252051,"d":"0.25"},{"v":2.137788,"d":"2.14"},{"v":0.117902710652319,"d":"0.12"},{"v":-3.08433120778509,"d":"-3.08"},{"v":7.90048063743895e-06,"d":"0.00"},{"v":0.000584527854190606,"d":"0.00"},"down","yes"]
[67223,"j","chr16","+",11549,14089,"MSTRG.5468.1",3,1475,"MSTRG.5468","DDX11L10","NA","NA","NA","NA","NA",{"v":1.518123,"d":"1.52"},{"v":12.254928,"d":"12.25"},{"v":0.123878573582807,"d":"0.12"},{"v":-3.0130014187807,"d":"-3.01"},{"v":7.93474549414492e-06,"d":"0.00"},{"v":0.000584527854190606,"d":"0.00"},"down","yes"]
[176933,"j","chr7","-",100572256,100586154,"MSTRG.13826.4",22,3643,"MSTRG.13826","LRCH4","NA","NA","NA","NA","NA",{"v":2.170217,"d":"2.17"},{"v":17.14636,"d":"17.15"},{"v":0.126570129170273,"d":"0.13"},{"v":-2.98199112916307,"d":"-2.98"},{"v":7.94612860204533e-06,"d":"0.00"},{"v":0.000584527854190606,"d":"0.00"},"down","yes"]
[117359,0,"chr2","+",190408355,190502315,"ENST00000392328",8,4797,"ENSG00000151690","MFSD6","GO:0016020(membrane);GO:0016021(integral component of membrane)","NA","NA","NA","major facilitator superfamily domain containing 6 [Source:HGNC Symbol;Acc:HGNC:24711]",{"v":2.975567,"d":"2.98"},{"v":0.276188,"d":"0.28"},{"v":10.7737012469767,"d":"10.77"},{"v":3.42944206002748,"d":"3.43"},{"v":8.02470574000843e-06,"d":"0.00"},{"v":0.00058603780832932,"d":"0.00"},"up","yes"]
[96565,0,"chr19","+",10808519,10831897,"ENST00000590806",7,5651,"MSTRG.7808","DNM2","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005794(Golgi apparatus);GO:0005525(GTP binding);GO:0000166(nucleotide binding);GO:0005829(cytosol);GO:0016787(hydrolase activity);GO:0006355(regulation of transcription, DNA-templated);GO:0003924(GTPase activity);GO:0006897(endocytosis);GO:0005886(plasma membrane);GO:0005856(cytoskeleton);GO:0042995(cell projection);GO:0005515(protein binding);GO:0007165(signal transduction);GO:0030054(cell junction);GO:0045202(synapse);GO:0045211(postsynaptic membrane);GO:0005874(microtubule);GO:0031410(cytoplasmic vesicle);GO:0005905(clathrin-coated pit);GO:0045893(positive regulation of transcription, DNA-templated);GO:0005925(focal adhesion);GO:0008017(microtubule binding);GO:0030496(midbody);GO:0048812(neuron projection morphogenesis);GO:0030426(growth cone);GO:0070062(extracellular exosome);GO:0001891(phagocytic cup);GO:0030670(phagocytic vesicle membrane);GO:0061024(membrane organization);GO:0043065(positive regulation of apoptotic process);GO:0014069(postsynaptic density);GO:0017124(SH3 domain binding);GO:0019886(antigen processing and presentation of exogenous peptide antigen via MHC class II);GO:0019899(enzyme binding);GO:0006909(phagocytosis);GO:0000139(Golgi membrane);GO:0050999(regulation of nitric-oxide synthase activity);GO:1903526(negative regulation of membrane tubulation);GO:0030666(endocytic vesicle membrane);GO:0048489(synaptic vesicle transport);GO:0000086(G2/M transition of mitotic cell cycle);GO:0003374(dynamin family protein polymerization involved in mitochondrial fission);GO:0006898(receptor-mediated endocytosis);GO:0061025(membrane fusion);GO:0031966(mitochondrial membrane);GO:0030516(regulation of axon extension);GO:0033572(transferrin transport);GO:0000266(mitochondrial fission);GO:0031623(receptor internalization);GO:0019901(protein kinase binding);GO:0031749(D2 dopamine receptor binding);GO:0032403(protein complex binding);GO:0036312(phosphatidylinositol 3-kinase regulatory subunit binding);GO:0050699(WW domain binding);GO:0050998(nitric-oxide synthase binding);GO:0002031(G-protein coupled receptor internalization);GO:0003281(ventricular septum development);GO:0006893(Golgi to plasma membrane transport);GO:0007283(spermatogenesis);GO:0009416(response to light stimulus);GO:0010592(positive regulation of lamellipodium assembly);GO:0030512(negative regulation of transforming growth factor beta receptor signaling pathway);GO:0035020(regulation of Rac protein signal transduction);GO:0035904(aorta development);GO:0042220(response to cocaine);GO:0044351(macropinocytosis);GO:0045429(positive regulation of nitric oxide biosynthetic process);GO:0045807(positive regulation of endocytosis);GO:0050766(positive regulation of phagocytosis);GO:0060976(coronary vasculature development);GO:0071245(cellular response to carbon monoxide);GO:0071481(cellular response to X-ray);GO:0071732(cellular response to nitric oxide);GO:1900026(positive regulation of substrate adhesion-dependent cell spreading);GO:1902856(negative regulation of non-motile cilium assembly);GO:1903351(cellular response to dopamine);GO:1903358(regulation of Golgi organization);GO:1903408(positive regulation of sodium:potassium-exchanging ATPase activity);GO:0001917(photoreceptor inner segment);GO:0005634(nucleus);GO:0005768(endosome);GO:0005802(trans-Golgi network);GO:0005813(centrosome);GO:0030027(lamellipodium);GO:0032587(ruffle membrane);GO:0043234(protein complex);GO:0045334(clathrin-coated endocytic vesicle);GO:0048471(perinuclear region of cytoplasm)","04072(Phospholipase D signaling pathway);04144(Endocytosis);04666(Fc gamma R-mediated phagocytosis);04961(Endocrine and other factor-regulated calcium reabsorption);04721(Synaptic vesicle cycle);05100(Bacterial invasion of epithelial cells)","NA","NA","dynamin 2 [Source:HGNC Symbol;Acc:HGNC:2974]",{"v":2.439234,"d":"2.44"},{"v":0.225114,"d":"0.23"},{"v":10.8355499880061,"d":"10.84"},{"v":3.43770047811418,"d":"3.44"},{"v":8.02982479502139e-06,"d":"0.00"},{"v":0.00058603780832932,"d":"0.00"},"up","yes"]
[83823,0,"chr17","+",42998436,43002959,"ENST00000588830",4,318,"MSTRG.6848","RPL27","GO:0003723(RNA binding);GO:0005634(nucleus);GO:0016020(membrane);GO:0006412(translation);GO:0030529(intracellular ribonucleoprotein complex);GO:0005622(intracellular);GO:0003735(structural constituent of ribosome);GO:0005840(ribosome);GO:0005925(focal adhesion);GO:0006364(rRNA processing);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0031012(extracellular matrix);GO:0006413(translational initiation);GO:0000184(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay);GO:0019083(viral transcription);GO:0006614(SRP-dependent cotranslational protein targeting to membrane);GO:0022625(cytosolic large ribosomal subunit)","03010(Ribosome)","NA","NA","ribosomal protein L27 [Source:HGNC Symbol;Acc:HGNC:10328]",{"v":3.883276,"d":"3.88"},{"v":31.921583,"d":"31.92"},{"v":0.121650483310931,"d":"0.12"},{"v":-3.0391860428486,"d":"-3.04"},{"v":8.05550251999066e-06,"d":"0.00"},{"v":0.00058603780832932,"d":"0.00"},"down","yes"]
[158369,"j","chr5","+",134113330,134148918,"MSTRG.12319.1",11,4713,"MSTRG.12319","TCF7","NA","NA","NA","NA","NA",{"v":7.713123,"d":"7.71"},{"v":0.737045,"d":"0.74"},{"v":10.4649281929869,"d":"10.46"},{"v":3.38749050719984,"d":"3.39"},{"v":8.33308051456676e-06,"d":"0.00"},{"v":0.000604010978836069,"d":"0.00"},"up","yes"]
[97972,0,"chr19","+",16197934,16235345,"ENST00000444449",13,2311,"MSTRG.7932","AP1M1","GO:0006810(transport);GO:0016020(membrane);GO:0006886(intracellular protein transport);GO:0015031(protein transport);GO:0016192(vesicle-mediated transport);GO:0005794(Golgi apparatus);GO:0030131(clathrin adaptor complex);GO:0005515(protein binding);GO:0031410(cytoplasmic vesicle);GO:0005886(plasma membrane);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0016032(viral process);GO:0043312(neutrophil degranulation);GO:0035579(specific granule membrane);GO:0019886(antigen processing and presentation of exogenous peptide antigen via MHC class II);GO:0032588(trans-Golgi network membrane);GO:0032438(melanosome organization);GO:0030665(clathrin-coated vesicle membrane);GO:0000139(Golgi membrane);GO:0005765(lysosomal membrane);GO:0050690(regulation of defense response to virus by virus);GO:0030659(cytoplasmic vesicle membrane);GO:0030669(clathrin-coated endocytic vesicle membrane);GO:0035646(endosome to melanosome transport)","04142(Lysosome)","K12393","NA","adaptor related protein complex 1 mu 1 subunit [Source:HGNC Symbol;Acc:HGNC:13667]",{"v":0.51849,"d":"0.52"},{"v":4.27364,"d":"4.27"},{"v":0.121322806787656,"d":"0.12"},{"v":-3.04307731486085,"d":"-3.04"},{"v":8.46791536038506E-6,"d":"0.00"},{"v":0.000611544193982845,"d":"0.00"},"down","yes"]
[170564,0,"chr6","-",159679116,159693228,"ENST00000367054",5,815,"MSTRG.13403","SOD2","GO:0046872(metal ion binding);GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0004784(superoxide dismutase activity);GO:0006801(superoxide metabolic process);GO:0003677(DNA binding);GO:0019825(oxygen binding);GO:0019899(enzyme binding);GO:0030145(manganese ion binding);GO:0042802(identical protein binding);GO:0000302(response to reactive oxygen species);GO:0000303(response to superoxide);GO:0001306(age-dependent response to oxidative stress);GO:0001666(response to hypoxia);GO:0001836(release of cytochrome c from mitochondria);GO:0001889(liver development);GO:0003032(detection of oxygen);GO:0003069(acetylcholine-mediated vasodilation involved in regulation of systemic arterial blood pressure);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0006749(glutathione metabolic process);GO:0006979(response to oxidative stress);GO:0007005(mitochondrion organization);GO:0007507(heart development);GO:0007568(aging);GO:0007626(locomotory behavior);GO:0008217(regulation of blood pressure);GO:0008630(intrinsic apoptotic signaling pathway in response to DNA damage);GO:0008631(intrinsic apoptotic signaling pathway in response to oxidative stress);GO:0008637(apoptotic mitochondrial changes);GO:0009314(response to radiation);GO:0009409(response to cold);GO:0009791(post-embryonic development);GO:0010042(response to manganese ion);GO:0010043(response to zinc ion);GO:0010269(response to selenium ion);GO:0010332(response to gamma radiation);GO:0014823(response to activity);GO:0019430(removal of superoxide radicals);GO:0022904(respiratory electron transport chain);GO:0030097(hemopoiesis);GO:0031667(response to nutrient levels);GO:0032496(response to lipopolysaccharide);GO:0033591(response to L-ascorbic acid);GO:0034021(response to silicon dioxide);GO:0035900(response to isolation stress);GO:0035902(response to immobilization stress);GO:0042311(vasodilation);GO:0042493(response to drug);GO:0042542(response to hydrogen peroxide);GO:0042554(superoxide anion generation);GO:0042743(hydrogen peroxide metabolic process);GO:0043066(negative regulation of apoptotic process);GO:0045429(positive regulation of nitric oxide biosynthetic process);GO:0045599(negative regulation of fat cell differentiation);GO:0046686(response to cadmium ion);GO:0048147(negative regulation of fibroblast proliferation);GO:0048666(neuron development);GO:0048678(response to axon injury);GO:0048773(erythrophore differentiation);GO:0050665(hydrogen peroxide biosynthetic process);GO:0050790(regulation of catalytic activity);GO:0051260(protein homooligomerization);GO:0051602(response to electrical stimulus);GO:0051881(regulation of mitochondrial membrane potential);GO:0055072(iron ion homeostasis);GO:0055093(response to hyperoxia);GO:0071000(response to magnetism);GO:0071361(cellular response to ethanol);GO:0005737(cytoplasm);GO:0005739(mitochondrion);GO:0005743(mitochondrial inner membrane);GO:0042645(mitochondrial nucleoid);GO:0043209(myelin sheath);GO:0008285(negative regulation of cell proliferation);GO:0030335(positive regulation of cell migration);GO:0005759(mitochondrial matrix);GO:0070062(extracellular exosome);GO:0035722(interleukin-12-mediated signaling pathway);GO:0051289(protein homotetramerization);GO:0034599(cellular response to oxidative stress);GO:0043524(negative regulation of neuron apoptotic process);GO:1902176(negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway);GO:0001315(age-dependent response to reactive oxygen species);GO:0032364(oxygen homeostasis)","04068(FoxO signaling pathway);04146(Peroxisome);04211(Longevity regulating pathway - mammal);04213(Longevity regulating pathway - multiple species);05016(Huntington's disease)","K04564","EC:1.15.1.1","superoxide dismutase 2 [Source:HGNC Symbol;Acc:HGNC:11180]",{"v":64.320877,"d":"64.32"},{"v":6.189134,"d":"6.19"},{"v":10.3925487798455,"d":"10.39"},{"v":3.37747761449035,"d":"3.38"},{"v":8.50829815846343e-06,"d":"0.00"},{"v":0.000612226196216998,"d":"0.00"},"up","yes"]
[95290,0,"chr19","+",5690306,5691653,"ENST00000579446",3,452,"MSTRG.7711","RPL36","GO:0003723(RNA binding);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0006412(translation);GO:0030529(intracellular ribonucleoprotein complex);GO:0005622(intracellular);GO:0003735(structural constituent of ribosome);GO:0005840(ribosome);GO:0005730(nucleolus);GO:0005829(cytosol);GO:0002181(cytoplasmic translation);GO:0006413(translational initiation);GO:0006364(rRNA processing);GO:0000184(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay);GO:0019083(viral transcription);GO:0006614(SRP-dependent cotranslational protein targeting to membrane);GO:0022625(cytosolic large ribosomal subunit)","03010(Ribosome)","NA","NA","ribosomal protein L36 [Source:HGNC Symbol;Acc:HGNC:13631]",{"v":4.884571,"d":"4.88"},{"v":39.095512,"d":"39.10"},{"v":0.124939430387815,"d":"0.12"},{"v":-3.00069923725682,"d":"-3.00"},{"v":8.6219950224484e-06,"d":"0.00"},{"v":0.00061815955617467,"d":"0.00"},"down","yes"]
[146812,"j","chr4","-",39454126,39458931,"MSTRG.11579.3",8,716,"MSTRG.11579","RPL9","NA","NA","NA","NA","NA",{"v":5.454901,"d":"5.45"},{"v":43.074238,"d":"43.07"},{"v":0.126639524070049,"d":"0.13"},{"v":-2.98120035614953,"d":"-2.98"},{"v":8.66783347652455e-06,"d":"0.00"},{"v":0.000619202486763422,"d":"0.00"},"down","yes"]
[170523,0,"chr6","-",158765741,158818227,"ENST00000337147",13,3068,"MSTRG.13387","EZR","GO:0045177(apical part of cell);GO:0003723(RNA binding);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0003779(actin binding);GO:0001650(fibrillar center);GO:0005886(plasma membrane);GO:0005829(cytosol);GO:0005856(cytoskeleton);GO:0042995(cell projection);GO:0005515(protein binding);GO:0008092(cytoskeletal protein binding);GO:0048471(perinuclear region of cytoplasm);GO:0005615(extracellular space);GO:0048015(phosphatidylinositol-mediated signaling);GO:0005925(focal adhesion);GO:0008017(microtubule binding);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0005768(endosome);GO:0045296(cadherin binding);GO:0051015(actin filament binding);GO:0030175(filopodium);GO:0070062(extracellular exosome);GO:0010628(positive regulation of gene expression);GO:0071944(cell periphery);GO:0005938(cell cortex);GO:0032587(ruffle membrane);GO:0016323(basolateral plasma membrane);GO:0071437(invadopodium);GO:0019898(extrinsic component of membrane);GO:0005903(brush border);GO:0008360(regulation of cell shape);GO:0001726(ruffle);GO:0016324(apical plasma membrane);GO:0019904(protein domain specific binding);GO:0051017(actin filament bundle assembly);GO:0031982(vesicle);GO:0007411(axon guidance);GO:0061028(establishment of endothelial barrier);GO:0050714(positive regulation of protein secretion);GO:0031528(microvillus membrane);GO:0098592(cytoplasmic side of apical plasma membrane);GO:0044548(S100 protein binding);GO:0070373(negative regulation of ERK1 and ERK2 cascade);GO:0030033(microvillus assembly);GO:0090002(establishment of protein localization to plasma membrane);GO:0015629(actin cytoskeleton);GO:0001772(immunological synapse);GO:0031532(actin cytoskeleton reorganization);GO:0034236(protein kinase A catalytic subunit binding);GO:0034237(protein kinase A regulatory subunit binding);GO:0071320(cellular response to cAMP);GO:0051117(ATPase binding);GO:0003376(sphingosine-1-phosphate signaling pathway);GO:0046847(filopodium assembly);GO:0005902(microvillus);GO:0044853(plasma membrane raft);GO:0050839(cell adhesion molecule binding);GO:0050860(negative regulation of T cell receptor signaling pathway);GO:0007159(leukocyte cell-cell adhesion);GO:0022614(membrane to membrane docking);GO:0010737(protein kinase A signaling);GO:1900041(negative regulation of interleukin-2 secretion);GO:0007016(cytoskeletal anchoring at plasma membrane);GO:0030953(astral microtubule organization);GO:0034629(cellular protein complex localization);GO:0043622(cortical microtubule organization);GO:0051660(establishment of centrosome localization);GO:0072697(protein localization to cell cortex);GO:1902115(regulation of organelle assembly);GO:1902966(positive regulation of protein localization to early endosome);GO:1903364(positive regulation of cellular protein catabolic process);GO:1903753(negative regulation of p38MAPK cascade);GO:2000643(positive regulation of early endosome to late endosome transport);GO:0005884(actin filament);GO:0030863(cortical cytoskeleton);GO:0008022(protein C-terminus binding);GO:0032403(protein complex binding);GO:0097718(disordered domain specific binding);GO:0001951(intestinal D-glucose absorption);GO:0030855(epithelial cell differentiation);GO:0031623(receptor internalization);GO:0032532(regulation of microvillus length);GO:0035088(establishment or maintenance of apical/basal cell polarity);GO:0040018(positive regulation of multicellular organism growth);GO:0090004(positive regulation of establishment of protein localization to plasma membrane);GO:1902896(terminal web assembly);GO:0001931(uropod);GO:0005622(intracellular);GO:0030315(T-tubule);GO:0036064(ciliary basal body);GO:0043209(myelin sheath);GO:0044297(cell body);GO:0044393(microspike);GO:0045121(membrane raft);GO:0051286(cell tip);GO:0097449(astrocyte projection);GO:0097454(Schwann cell microvillus)","04530(Tight junction);04810(Regulation of actin cytoskeleton);04670(Leukocyte transendothelial migration);04971(Gastric acid secretion);05206(MicroRNAs in cancer);05205(Proteoglycans in cancer);05130(Pathogenic Escherichia coli infection)","K08007","NA","ezrin [Source:HGNC Symbol;Acc:HGNC:12691]",{"v":26.693489,"d":"26.69"},{"v":2.591785,"d":"2.59"},{"v":10.2992682649217,"d":"10.30"},{"v":3.36446993636681,"d":"3.36"},{"v":8.7357778564893E-6,"d":"0.00"},{"v":0.000621811410878454,"d":"0.00"},"up","yes"]
[199344,0,"chrX","+",110003095,110177788,"ENST00000372073",7,5567,"MSTRG.15402","TMEM164","GO:0016020(membrane);GO:0016021(integral component of membrane)","NA","NA","NA","transmembrane protein 164 [Source:HGNC Symbol;Acc:HGNC:26217]",{"v":0.151165,"d":"0.15"},{"v":1.264852,"d":"1.26"},{"v":0.119512006147755,"d":"0.12"},{"v":-3.06477253659971,"d":"-3.06"},{"v":8.81955722335232e-06,"d":"0.00"},{"v":0.000625081520468691,"d":"0.00"},"down","yes"]
[70198,0,"chr16","-",18782968,18790334,"ENST00000562935",5,427,"MSTRG.5711","RPS15A","GO:0003723(RNA binding);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0006412(translation);GO:0030529(intracellular ribonucleoprotein complex);GO:0003735(structural constituent of ribosome);GO:0005840(ribosome);GO:0022627(cytosolic small ribosomal subunit);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0009615(response to virus);GO:0031012(extracellular matrix);GO:0005739(mitochondrion);GO:0005515(protein binding);GO:0008284(positive regulation of cell proliferation);GO:0006413(translational initiation);GO:0006364(rRNA processing);GO:0045787(positive regulation of cell cycle);GO:0000184(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay);GO:0019083(viral transcription);GO:0006614(SRP-dependent cotranslational protein targeting to membrane)","03010(Ribosome)","NA","NA","ribosomal protein S15a [Source:HGNC Symbol;Acc:HGNC:10389]",{"v":3.229664,"d":"3.23"},{"v":26.25705,"d":"26.26"},{"v":0.123001784282697,"d":"0.12"},{"v":-3.02324885121611,"d":"-3.02"},{"v":8.84489719684827e-06,"d":"0.00"},{"v":0.000625081520468691,"d":"0.00"},"down","yes"]
[99850,0,"chr19","+",34677689,34686391,"ENST00000423823",5,2590,"ENSG00000089335","ZNF302","GO:0003676(nucleic acid binding);GO:0006355(regulation of transcription, DNA-templated);GO:0005622(intracellular);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0003700(transcription factor activity, sequence-specific DNA binding)","NA","NA","NA","zinc finger protein 302 [Source:HGNC Symbol;Acc:HGNC:13848]",{"v":0.375176,"d":"0.38"},{"v":3.085784,"d":"3.09"},{"v":0.121582067960687,"d":"0.12"},{"v":-3.03999763232217,"d":"-3.04"},{"v":8.9217958700777e-06,"d":"0.00"},{"v":0.000628272230167607,"d":"0.00"},"down","yes"]
[4684,0,"chr1","-",40072729,40097252,"ENST00000439754",8,2195,"MSTRG.463","PPT1","GO:0005615(extracellular space);GO:0044257(cellular protein catabolic process);GO:0005764(lysosome);GO:0043025(neuronal cell body);GO:0030424(axon);GO:0007601(visual perception);GO:0030425(dendrite);GO:0008474(palmitoyl-(protein) hydrolase activity);GO:0002084(protein depalmitoylation);GO:0007040(lysosome organization);GO:0007269(neurotransmitter secretion);GO:0007625(grooming behavior);GO:0008306(associative learning);GO:0008344(adult locomotory behavior);GO:0032429(regulation of phospholipase A2 activity);GO:0044265(cellular macromolecule catabolic process);GO:0008021(synaptic vesicle);GO:0043005(neuron projection);GO:0045202(synapse);GO:0098599(palmitoyl hydrolase activity);GO:0005634(nucleus);GO:0016020(membrane);GO:0015031(protein transport);GO:0016787(hydrolase activity);GO:0005794(Golgi apparatus);GO:0016042(lipid catabolic process);GO:0005829(cytosol);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0007399(nervous system development);GO:0045121(membrane raft);GO:0050896(response to stimulus);GO:0048666(neuron development);GO:0070062(extracellular exosome);GO:0043524(negative regulation of neuron apoptotic process);GO:0016290(palmitoyl-CoA hydrolase activity);GO:0043066(negative regulation of apoptotic process);GO:0030308(negative regulation of cell growth);GO:0048260(positive regulation of receptor-mediated endocytosis);GO:0007268(chemical synaptic transmission);GO:0007420(brain development);GO:0043202(lysosomal lumen);GO:0046949(fatty-acyl-CoA biosynthetic process);GO:0030163(protein catabolic process);GO:0031579(membrane raft organization);GO:0007042(lysosomal lumen acidification);GO:0030149(sphingolipid catabolic process);GO:0050803(regulation of synapse structure or activity);GO:0006898(receptor-mediated endocytosis);GO:0006907(pinocytosis);GO:0048549(positive regulation of pinocytosis);GO:0051181(cofactor transport);GO:0051186(cofactor metabolic process)","00062(Fatty acid elongation);04142(Lysosome)","K01074","EC:3.1.2.22","palmitoyl-protein thioesterase 1 [Source:HGNC Symbol;Acc:HGNC:9325]",{"v":2.095378,"d":"2.10"},{"v":16.406454,"d":"16.41"},{"v":0.127716690029424,"d":"0.13"},{"v":-2.96898102599931,"d":"-2.97"},{"v":9.04566830500877e-06,"d":"0.00"},{"v":0.0006342066808533,"d":"0.00"},"down","yes"]
[188042,0,"chr8","-",143612618,143617482,"ENST00000529064",11,1324,"MSTRG.14613","TSTA3","GO:0005737(cytoplasm);GO:0016853(isomerase activity);GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0003824(catalytic activity);GO:0008152(metabolic process);GO:0050662(coenzyme binding);GO:0042802(identical protein binding);GO:0009226(nucleotide-sugar biosynthetic process);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0009055(electron carrier activity);GO:0019673(GDP-mannose metabolic process);GO:0042351('de novo' GDP-L-fucose biosynthetic process);GO:0007159(leukocyte cell-cell adhesion);GO:0042356(GDP-4-dehydro-D-rhamnose reductase activity);GO:0050577(GDP-L-fucose synthase activity);GO:0019835(cytolysis)","00051(Fructose and mannose metabolism);00520(Amino sugar and nucleotide sugar metabolism)","NA","NA","tissue specific transplantation antigen P35B [Source:HGNC Symbol;Acc:HGNC:12390]",{"v":0.622372,"d":"0.62"},{"v":5.21431,"d":"5.21"},{"v":0.119358457782525,"d":"0.12"},{"v":-3.06662729496472,"d":"-3.07"},{"v":9.08660269748386e-06,"d":"0.00"},{"v":0.0006342066808533,"d":"0.00"},"down","yes"]
[181088,0,"chr8","-",9136255,9150696,"ENST00000310455",2,5548,"MSTRG.14189","PPP1R3B","GO:0050790(regulation of catalytic activity);GO:0019888(protein phosphatase regulator activity);GO:0006470(protein dephosphorylation);GO:0005975(carbohydrate metabolic process);GO:0005977(glycogen metabolic process);GO:0004721(phosphoprotein phosphatase activity);GO:0019899(enzyme binding);GO:0005979(regulation of glycogen biosynthetic process);GO:0005981(regulation of glycogen catabolic process);GO:0000164(protein phosphatase type 1 complex);GO:0042587(glycogen granule);GO:0043231(intracellular membrane-bounded organelle)","04910(Insulin signaling pathway);04931(Insulin resistance)","K07189","NA","protein phosphatase 1 regulatory subunit 3B [Source:HGNC Symbol;Acc:HGNC:14942]",{"v":1.295109,"d":"1.30"},{"v":10.056842,"d":"10.06"},{"v":0.128778895005013,"d":"0.13"},{"v":-2.95703191887636,"d":"-2.96"},{"v":9.10221838297641e-06,"d":"0.00"},{"v":0.0006342066808533,"d":"0.00"},"down","yes"]
[54893,0,"chr14","-",50719763,50831121,"ENST00000245441",31,10293,"MSTRG.4381","NIN","GO:0005509(calcium ion binding);GO:0005813(centrosome);GO:0034454(microtubule anchoring at centrosome);GO:0005737(cytoplasm);GO:0000166(nucleotide binding);GO:0005634(nucleus);GO:0005730(nucleolus);GO:0005525(GTP binding);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0005874(microtubule);GO:0005815(microtubule organizing center);GO:0005814(centriole);GO:0097539(ciliary transition fiber);GO:0000922(spindle pole);GO:0000242(pericentriolar material);GO:0051642(centrosome localization);GO:0090222(centrosome-templated microtubule nucleation);GO:0036449(microtubule minus-end);GO:0097431(mitotic spindle pole)","NA","NA","NA","ninein [Source:HGNC Symbol;Acc:HGNC:14906]",{"v":7.184853,"d":"7.18"},{"v":0.70126,"d":"0.70"},{"v":10.2456335738528,"d":"10.25"},{"v":3.35693729598548,"d":"3.36"},{"v":9.1726632903124e-06,"d":"0.00"},{"v":6.36872495398953E-4,"d":"0.00"},"up","yes"]
[33236,0,"chr11","-",75434640,75525903,"ENST00000336898",17,3523,"ENSG00000158555","GDPD5","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016787(hydrolase activity);GO:0006629(lipid metabolic process);GO:0042995(cell projection);GO:0005515(protein binding);GO:0048471(perinuclear region of cytoplasm);GO:0007399(nervous system development);GO:0008081(phosphoric diester hydrolase activity);GO:0030426(growth cone);GO:0012505(endomembrane system);GO:0008889(glycerophosphodiester phosphodiesterase activity);GO:0047389(glycerophosphocholine phosphodiesterase activity);GO:0021522(spinal cord motor neuron differentiation);GO:0021895(cerebral cortex neuron differentiation);GO:0031175(neuron projection development);GO:0045666(positive regulation of neuron differentiation);GO:0045746(negative regulation of Notch signaling pathway);GO:0045787(positive regulation of cell cycle);GO:0048505(regulation of timing of cell differentiation);GO:0030424(axon);GO:0043025(neuronal cell body);GO:0097038(perinuclear endoplasmic reticulum)","NA","NA","NA","glycerophosphodiester phosphodiesterase domain containing 5 [Source:HGNC Symbol;Acc:HGNC:28804]",{"v":2.381381,"d":"2.38"},{"v":0.21544,"d":"0.22"},{"v":11.053569439287,"d":"11.05"},{"v":3.46644041751832,"d":"3.47"},{"v":9.50855195991954e-06,"d":"0.00"},{"v":0.000655690485764557,"d":"0.00"},"up","yes"]
[159912,0,"chr5","+",149345430,149354583,"ENST00000329271",4,4089,"ENSG00000164284","GRPEL2","GO:0005739(mitochondrion);GO:0006457(protein folding);GO:0050790(regulation of catalytic activity);GO:0042803(protein homodimerization activity);GO:0051087(chaperone binding);GO:0000774(adenyl-nucleotide exchange factor activity);GO:0005759(mitochondrial matrix);GO:0030150(protein import into mitochondrial matrix);GO:0051082(unfolded protein binding);GO:0001405(presequence translocase-associated import motor);GO:0005743(mitochondrial inner membrane)","NA","NA","NA","GrpE like 2, mitochondrial [Source:HGNC Symbol;Acc:HGNC:21060]",{"v":3.359513,"d":"3.36"},{"v":0.316591,"d":"0.32"},{"v":10.6115240167914,"d":"10.61"},{"v":3.40755996448336,"d":"3.41"},{"v":9.51773289832621e-06,"d":"0.00"},{"v":0.000655690485764557,"d":"0.00"},"up","yes"]
[21305,0,"chr10","+",73744384,73772159,"ENST00000465076",22,4668,"MSTRG.1807","SEC24C","GO:0006810(transport);GO:0006886(intracellular protein transport);GO:0015031(protein transport);GO:0008270(zinc ion binding);GO:0006888(ER to Golgi vesicle-mediated transport);GO:0030127(COPII vesicle coat);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005794(Golgi apparatus);GO:0005829(cytosol);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005515(protein binding);GO:0000139(Golgi membrane);GO:0048471(perinuclear region of cytoplasm);GO:0016192(vesicle-mediated transport);GO:0003674(molecular_function);GO:0000149(SNARE binding);GO:0019886(antigen processing and presentation of exogenous peptide antigen via MHC class II);GO:0048208(COPII vesicle coating);GO:0012507(ER to Golgi transport vesicle membrane);GO:0002474(antigen processing and presentation of peptide antigen via MHC class I);GO:0090110(cargo loading into COPII-coated vesicle);GO:0001701(in utero embryonic development)","04141(Protein processing in endoplasmic reticulum)","NA","NA","SEC24 homolog C, COPII coat complex component [Source:HGNC Symbol;Acc:HGNC:10705]",{"v":5.389975,"d":"5.39"},{"v":0.518171,"d":"0.52"},{"v":10.4019233033111,"d":"10.40"},{"v":3.37877840052393,"d":"3.38"},{"v":9.54309985345626e-06,"d":"0.00"},{"v":0.000655690485764557,"d":"0.00"},"up","yes"]
[17163,0,"chr1","-",235167884,235328134,"ENST00000421364",25,5151,"MSTRG.1477","ARID4B","GO:0006355(regulation of transcription, DNA-templated);GO:0005634(nucleus);GO:0003677(DNA binding);GO:0005737(cytoplasm);GO:0006351(transcription, DNA-templated);GO:0016575(histone deacetylation);GO:0005515(protein binding);GO:0003674(molecular_function);GO:0008150(biological_process);GO:0005575(cellular_component);GO:0005654(nucleoplasm);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0004407(histone deacetylase activity);GO:0044212(transcription regulatory region DNA binding);GO:0006349(regulation of gene expression by genetic imprinting);GO:0007283(spermatogenesis);GO:0034773(histone H4-K20 trimethylation);GO:0036124(histone H3-K9 trimethylation);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0097368(establishment of Sertoli cell barrier)","NA","NA","NA","AT-rich interaction domain 4B [Source:HGNC Symbol;Acc:HGNC:15550]",{"v":1.593244,"d":"1.59"},{"v":0.145864,"d":"0.15"},{"v":10.9228048044754,"d":"10.92"},{"v":3.4492714601128,"d":"3.45"},{"v":9.9308572037484e-06,"d":"0.00"},{"v":6.79351112477983E-4,"d":"0.00"},"up","yes"]
[149124,0,"chr4","+",87007396,87135701,"ENST00000544085",20,3648,"MSTRG.11708","AFF1","GO:0005634(nucleus);GO:0005515(protein binding);GO:0006355(regulation of transcription, DNA-templated);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0008023(transcription elongation factor complex)","05202(Transcriptional misregulation in cancers)","K15184","NA","AF4/FMR2 family member 1 [Source:HGNC Symbol;Acc:HGNC:7135]",{"v":9.914124,"d":"9.91"},{"v":0.969371,"d":"0.97"},{"v":10.2273783721609,"d":"10.23"},{"v":3.35436447514205,"d":"3.35"},{"v":9.95612606724354e-06,"d":"0.00"},{"v":6.79351112477983E-4,"d":"0.00"},"up","yes"]
[88299,0,"chr17","+",75979231,76005998,"ENST00000567351",9,3897,"MSTRG.7231","TEN1-CDK3","NA","NA","NA","NA","TEN1-CDK3 readthrough (NMD candidate) [Source:HGNC Symbol;Acc:HGNC:44420]",{"v":0.315969,"d":"0.32"},{"v":2.533608,"d":"2.53"},{"v":0.124711083956161,"d":"0.12"},{"v":-3.0033384015084,"d":"-3.00"},{"v":1.00855727694947E-5,"d":"0.00"},{"v":0.000685818948325642,"d":"0.00"},"down","yes"]
[52421,0,"chr14","+",20781051,20782467,"ENST00000304677",2,1061,"MSTRG.4134","RNASE6","GO:0003676(nucleic acid binding);GO:0016787(hydrolase activity);GO:0090305(nucleic acid phosphodiester bond hydrolysis);GO:0005576(extracellular region);GO:0004519(endonuclease activity);GO:0004518(nuclease activity);GO:0005615(extracellular space);GO:0031410(cytoplasmic vesicle);GO:0045087(innate immune response);GO:0051607(defense response to virus);GO:0070062(extracellular exosome);GO:0050829(defense response to Gram-negative bacterium);GO:0005622(intracellular);GO:0019731(antibacterial humoral response);GO:0050830(defense response to Gram-positive bacterium);GO:0061844(antimicrobial humoral immune response mediated by antimicrobial peptide);GO:0019730(antimicrobial humoral response);GO:0004540(ribonuclease activity);GO:0006401(RNA catabolic process);GO:0006952(defense response);GO:0090501(RNA phosphodiester bond hydrolysis)","NA","NA","NA","ribonuclease A family member k6 [Source:HGNC Symbol;Acc:HGNC:10048]",{"v":8.390823,"d":"8.39"},{"v":0.779531,"d":"0.78"},{"v":10.7639375470636,"d":"10.76"},{"v":3.42813402040948,"d":"3.43"},{"v":1.0250325403036E-5,"d":"0.00"},{"v":6.94635065326287E-4,"d":"0.00"},"up","yes"]
[100083,"j","chr19","+",35448269,35453515,"MSTRG.8072.2",3,4036,"MSTRG.8072","FFAR2","NA","NA","NA","NA","NA",{"v":21.019234,"d":"21.02"},{"v":2.085025,"d":"2.09"},{"v":10.0810465102337,"d":"10.08"},{"v":3.33357350721289,"d":"3.33"},{"v":1.0293447358166E-5,"d":"0.00"},{"v":0.000695176574482552,"d":"0.00"},"up","yes"]
[182999,0,"chr8","+",38105793,38139703,"ENST00000428278",16,2678,"MSTRG.14306","ASH2L","GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0016569(covalent chromatin modification);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0005654(nucleoplasm);GO:0008284(positive regulation of cell proliferation);GO:0044212(transcription regulatory region DNA binding);GO:1904837(beta-catenin-TCF complex assembly);GO:0035097(histone methyltransferase complex);GO:0006366(transcription from RNA polymerase II promoter);GO:0030097(hemopoiesis);GO:0018024(histone-lysine N-methyltransferase activity);GO:0043627(response to estrogen);GO:0045652(regulation of megakaryocyte differentiation);GO:0051568(histone H3-K4 methylation);GO:0044666(MLL3/4 complex);GO:0008013(beta-catenin binding);GO:0042800(histone methyltransferase activity (H3-K4 specific));GO:0048188(Set1C/COMPASS complex);GO:0006974(cellular response to DNA damage stimulus);GO:1990188(euchromatin binding);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0005719(nuclear euchromatin);GO:0071339(MLL1 complex)","NA","NA","NA","ASH2 like histone lysine methyltransferase complex subunit [Source:HGNC Symbol;Acc:HGNC:744]",{"v":0.780205,"d":"0.78"},{"v":6.096589,"d":"6.10"},{"v":0.127974019570616,"d":"0.13"},{"v":-2.96607714123265,"d":"-2.97"},{"v":1.04789990187764e-05,"d":"0.00"},{"v":0.000705300791100503,"d":"0.00"},"down","yes"]
[118898,0,"chr2","+",216498867,216501467,"ENST00000359681",3,742,"MSTRG.9408","RPL37A","GO:0003723(RNA binding);GO:0005634(nucleus);GO:0006412(translation);GO:0046872(metal ion binding);GO:0030529(intracellular ribonucleoprotein complex);GO:0005622(intracellular);GO:0003735(structural constituent of ribosome);GO:0005840(ribosome);GO:0005515(protein binding);GO:0005925(focal adhesion);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0006413(translational initiation);GO:0006364(rRNA processing);GO:0000184(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay);GO:0019083(viral transcription);GO:0006614(SRP-dependent cotranslational protein targeting to membrane);GO:0022625(cytosolic large ribosomal subunit)","03010(Ribosome)","NA","NA","ribosomal protein L37a [Source:HGNC Symbol;Acc:HGNC:10348]",{"v":41.424194,"d":"41.42"},{"v":4.068517,"d":"4.07"},{"v":10.1816445648378,"d":"10.18"},{"v":3.34789870285411,"d":"3.35"},{"v":1.05930268762713e-05,"d":"0.00"},{"v":0.00071055869772087,"d":"0.00"},"up","yes"]
[135741,0,"chr3","+",47802928,47850193,"ENST00000445061",22,4065,"MSTRG.10895","DHX30","GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0005737(cytoplasm);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0005829(cytosol);GO:0016787(hydrolase activity);GO:0005739(mitochondrion);GO:0004386(helicase activity);GO:0005515(protein binding);GO:0042254(ribosome biogenesis);GO:0004004(ATP-dependent RNA helicase activity);GO:0003682(chromatin binding);GO:0042645(mitochondrial nucleoid);GO:0003725(double-stranded RNA binding);GO:0035770(ribonucleoprotein granule);GO:0006396(RNA processing);GO:1902775(mitochondrial large ribosomal subunit assembly)","NA","NA","NA","DExH-box helicase 30 [Source:HGNC Symbol;Acc:HGNC:16716]",{"v":0.181587,"d":"0.18"},{"v":1.487121,"d":"1.49"},{"v":0.122106405598468,"d":"0.12"},{"v":-3.03378921001869,"d":"-3.03"},{"v":1.06613319666852E-5,"d":"0.00"},{"v":0.000712724449178263,"d":"0.00"},"down","yes"]
[52831,"j","chr14","+",22488593,22552158,"MSTRG.4204.7",6,1040,"MSTRG.4204","TRAC","NA","NA","NA","NA","NA",{"v":42.172531,"d":"42.17"},{"v":4.18957,"d":"4.19"},{"v":10.066076232167,"d":"10.07"},{"v":3.33142952365966,"d":"3.33"},{"v":1.10127729283933E-5,"d":"0.00"},{"v":0.000730052832337287,"d":"0.00"},"up","yes"]
[105526,"j","chr19","+",54449103,54462037,"MSTRG.8421.3",15,6015,"MSTRG.8421","LENG8","NA","NA","NA","NA","NA",{"v":3.61398,"d":"3.61"},{"v":0.354687,"d":"0.35"},{"v":10.1892090772991,"d":"10.19"},{"v":3.34897016360957,"d":"3.35"},{"v":1.10290408406248e-05,"d":"0.00"},{"v":0.000730052832337287,"d":"0.00"},"up","yes"]
[196822,0,"chrX","-",47624214,47630305,"ENST00000247153",10,1713,"MSTRG.15263","CFP","GO:0005576(extracellular region);GO:0002376(immune system process);GO:0045087(innate immune response);GO:0006956(complement activation);GO:0030449(regulation of complement activation);GO:0031012(extracellular matrix);GO:0043312(neutrophil degranulation);GO:0006955(immune response);GO:0005615(extracellular space);GO:0005788(endoplasmic reticulum lumen);GO:0035580(specific granule lumen);GO:1904724(tertiary granule lumen);GO:0042742(defense response to bacterium);GO:0006957(complement activation, alternative pathway);GO:0036066(protein O-linked fucosylation)","05168(Herpes simplex infection)","K15412","NA","complement factor properdin [Source:HGNC Symbol;Acc:HGNC:8864]",{"v":8.856219,"d":"8.86"},{"v":0.849685,"d":"0.85"},{"v":10.4229437968188,"d":"10.42"},{"v":3.38169089661761,"d":"3.38"},{"v":1.10312207837502e-05,"d":"0.00"},{"v":0.000730052832337287,"d":"0.00"},"up","yes"]
[144857,0,"chr3","+",197950194,197955851,"ENST00000448864",5,549,"MSTRG.11477","RPL35A","GO:0003723(RNA binding);GO:0016020(membrane);GO:0006412(translation);GO:0030529(intracellular ribonucleoprotein complex);GO:0005622(intracellular);GO:0003735(structural constituent of ribosome);GO:0005840(ribosome);GO:0000049(tRNA binding);GO:0006364(rRNA processing);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0031012(extracellular matrix);GO:0042273(ribosomal large subunit biogenesis);GO:0005515(protein binding);GO:0002181(cytoplasmic translation);GO:0006413(translational initiation);GO:0000184(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay);GO:0019083(viral transcription);GO:0006614(SRP-dependent cotranslational protein targeting to membrane);GO:0022625(cytosolic large ribosomal subunit)","03010(Ribosome)","K02917","NA","ribosomal protein L35a [Source:HGNC Symbol;Acc:HGNC:10345]",{"v":239.594986,"d":"239.59"},{"v":24.126762,"d":"24.13"},{"v":9.9306730841047,"d":"9.93"},{"v":3.31189150447983,"d":"3.31"},{"v":1.12828963097355e-05,"d":"0.00"},{"v":7.44219840590153E-4,"d":"0.00"},"up","yes"]
[181833,"j","chr8","+",20197367,20226844,"MSTRG.14206.1",15,7399,"MSTRG.14206","ATP6V1B2","NA","NA","NA","NA","NA",{"v":25.386515,"d":"25.39"},{"v":2.56735,"d":"2.57"},{"v":9.88821742263423,"d":"9.89"},{"v":3.30571046564395,"d":"3.31"},{"v":1.15155957035353E-5,"d":"0.00"},{"v":0.000757045208576602,"d":"0.00"},"up","yes"]
[31339,0,"chr11","-",65653601,65662895,"ENST00000525693",10,3183,"MSTRG.2557","RELA","GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0006355(regulation of transcription, DNA-templated);GO:0006366(transcription from RNA polymerase II promoter);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0031490(chromatin DNA binding);GO:0042803(protein homodimerization activity);GO:0005515(protein binding);GO:0051092(positive regulation of NF-kappaB transcription factor activity);GO:0045893(positive regulation of transcription, DNA-templated);GO:0006954(inflammatory response);GO:0038095(Fc-epsilon receptor signaling pathway);GO:0042802(identical protein binding);GO:0071159(NF-kappaB complex);GO:0051607(defense response to virus);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:0001078(transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0005654(nucleoplasm);GO:0019901(protein kinase binding);GO:0002223(stimulatory C-type lectin receptor signaling pathway);GO:0050852(T cell receptor signaling pathway);GO:0003682(chromatin binding);GO:0071347(cellular response to interleukin-1);GO:0071356(cellular response to tumor necrosis factor);GO:0016032(viral process);GO:0031625(ubiquitin protein ligase binding);GO:0043123(positive regulation of I-kappaB kinase/NF-kappaB signaling);GO:0008284(positive regulation of cell proliferation);GO:0047485(protein N-terminus binding);GO:0043066(negative regulation of apoptotic process);GO:0008134(transcription factor binding);GO:0044212(transcription regulatory region DNA binding);GO:0045892(negative regulation of transcription, DNA-templated);GO:0000790(nuclear chromatin);GO:0046982(protein heterodimerization activity);GO:0010033(response to organic substance);GO:0001077(transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0000977(RNA polymerase II regulatory region sequence-specific DNA binding);GO:1902895(positive regulation of pri-miRNA transcription from RNA polymerase II promoter);GO:0032481(positive regulation of type I interferon production);GO:0019221(cytokine-mediated signaling pathway);GO:0042826(histone deacetylase binding);GO:0051059(NF-kappaB binding);GO:0070555(response to interleukin-1);GO:0043620(regulation of DNA-templated transcription in response to stress);GO:1901223(negative regulation of NIK/NF-kappaB signaling);GO:0005667(transcription factor complex);GO:0071223(cellular response to lipoteichoic acid);GO:0000983(transcription factor activity, RNA polymerase II core promoter sequence-specific);GO:0006968(cellular defense response);GO:0050727(regulation of inflammatory response);GO:1901224(positive regulation of NIK/NF-kappaB signaling);GO:0070301(cellular response to hydrogen peroxide);GO:0042301(phosphate ion binding);GO:0003705(transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding);GO:2000630(positive regulation of miRNA metabolic process);GO:2001237(negative regulation of extrinsic apoptotic signaling pathway);GO:0010224(response to UV-B);GO:0031293(membrane protein intracellular domain proteolysis);GO:0000980(RNA polymerase II distal enhancer sequence-specific DNA binding);GO:0001205(transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding);GO:0071375(cellular response to peptide hormone stimulus);GO:0042805(actinin binding);GO:0071316(cellular response to nicotine);GO:0071354(cellular response to interleukin-6);GO:0070491(repressing transcription factor binding);GO:0050862(positive regulation of T cell receptor signaling pathway);GO:0033209(tumor necrosis factor-mediated signaling pathway);GO:0033613(activating transcription factor binding);GO:1901222(regulation of NIK/NF-kappaB signaling);GO:0033256(I-kappaB/NF-kappaB complex);GO:0001046(core promoter sequence-specific DNA binding);GO:0019899(enzyme binding);GO:0032403(protein complex binding);GO:0043565(sequence-specific DNA binding);GO:0071532(ankyrin repeat binding);GO:0001889(liver development);GO:0001942(hair follicle development);GO:0006117(acetaldehyde metabolic process);GO:0006952(defense response);GO:0007568(aging);GO:0009612(response to mechanical stimulus);GO:0009617(response to bacterium);GO:0009887(animal organ morphogenesis);GO:0010035(response to inorganic substance);GO:0014040(positive regulation of Schwann cell differentiation);GO:0014070(response to organic cyclic compound);GO:0032332(positive regulation of chondrocyte differentiation);GO:0032495(response to muramyl dipeptide);GO:0032496(response to lipopolysaccharide);GO:0032570(response to progesterone);GO:0032868(response to insulin);GO:0033234(negative regulation of protein sumoylation);GO:0033590(response to cobalamin);GO:0034097(response to cytokine);GO:0035729(cellular response to hepatocyte growth factor stimulus);GO:0035994(response to muscle stretch);GO:0042177(negative regulation of protein catabolic process);GO:0042493(response to drug);GO:0042542(response to hydrogen peroxide);GO:0043200(response to amino acid);GO:0043278(response to morphine);GO:0045084(positive regulation of interleukin-12 biosynthetic process);GO:0046627(negative regulation of insulin receptor signaling pathway);GO:0051591(response to cAMP);GO:0070431(nucleotide-binding oligomerization domain containing 2 signaling pathway);GO:0071222(cellular response to lipopolysaccharide);GO:0071224(cellular response to peptidoglycan);GO:1901522(positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus);GO:0035525(NF-kappaB p50/p65 complex);GO:0043234(protein complex)","04014(Ras signaling pathway);04010(MAPK signaling pathway);04064(NF-kappa B signaling pathway);04668(TNF signaling pathway);04066(HIF-1 signaling pathway);04071(Sphingolipid signaling pathway);04024(cAMP signaling pathway);04151(PI3K-Akt signaling pathway);04137(Mitophagy - animal);04210(Apoptosis);04218(Cellular senescence);04620(Toll-like receptor signaling pathway);04621(NOD-like receptor signaling pathway);04622(RIG-I-like receptor signaling pathway);04623(Cytosolic DNA-sensing pathway);04660(T cell receptor signaling pathway);04658(Th1 and Th2 cell differentiation);04659(Th17 cell differentiation);04657(IL-17 signaling pathway);04662(B cell receptor signaling pathway);04062(Chemokine signaling pathway);04920(Adipocytokine signaling pathway);04917(Prolactin signaling pathway);04926(Relaxin signaling pathway);04722(Neurotrophin signaling pathway);04380(Osteoclast differentiation);04211(Longevity regulating pathway - mammal);05200(Pathways in cancer);05202(Transcriptional misregulation in cancers);05203(Viral carcinogenesis);05212(Pancreatic cancer);05221(Acute myeloid leukemia);05220(Chronic myeloid leukemia);05215(Prostate cancer);05222(Small cell lung cancer);05321(Inflammatiory bowel disease (IBD));05030(Cocaine addiction);05418(Fluid shear stress and atherosclerosis);04932(Non-alcoholic fatty liver disease (NAFLD));04931(Insulin resistance);04933(AGE-RAGE signaling pathway in diabetic complications);05120(Epithelial cell signaling in Helicobacter pylori infection);05132(Salmonella infection);05131(Shigellosis);05133(Pertussis);05134(Legionellosis);05152(Tuberculosis);05166(HTLV-I infection);05162(Measles);05164(Influenza A);05161(Hepatitis B);05160(Hepatitis C);05168(Herpes simplex infection);05167(Kaposi's sarcoma-associated herpesvirus infection);05169(Epstein-Barr virus infection);05165(Human papillomavirus infection);05146(Amoebiasis);05145(Toxoplasmosis);05140(Leishmaniasis);05142(Chagas disease (American trypanosomiasis));01523(Antifolate resistance)","NA","NA","RELA proto-oncogene, NF-kB subunit [Source:HGNC Symbol;Acc:HGNC:9955]",{"v":0.39735,"d":"0.40"},{"v":3.107131,"d":"3.11"},{"v":0.127883246634918,"d":"0.13"},{"v":-2.96710081878235,"d":"-2.97"},{"v":1.18424948103031e-05,"d":"0.00"},{"v":0.000775957904987673,"d":"0.00"},"down","yes"]
[194426,0,"chr9","-",133097720,133149334,"ENST00000393160",18,3801,"MSTRG.15067","RALGDS","GO:0005622(intracellular);GO:0007264(small GTPase mediated signal transduction);GO:0043547(positive regulation of GTPase activity);GO:0005085(guanyl-nucleotide exchange factor activity);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0007165(signal transduction);GO:0005829(cytosol);GO:0050790(regulation of catalytic activity);GO:0005515(protein binding);GO:0005903(brush border);GO:0030695(GTPase regulator activity);GO:0007265(Ras protein signal transduction)","04014(Ras signaling pathway);04015(Rap1 signaling pathway);04072(Phospholipase D signaling pathway);05200(Pathways in cancer);05231(Choline metabolism in cancer);05210(Colorectal cancer);05212(Pancreatic cancer)","K08732","NA","ral guanine nucleotide dissociation stimulator [Source:HGNC Symbol;Acc:HGNC:9842]",{"v":3.883639,"d":"3.88"},{"v":0.377689,"d":"0.38"},{"v":10.2826373021189,"d":"10.28"},{"v":3.36213843088939,"d":"3.36"},{"v":1.20504994741127e-05,"d":"0.00"},{"v":0.000786244292645308,"d":"0.00"},"up","yes"]
[87232,0,"chr17","+",67825665,67983153,"ENST00000306378",28,9688,"ENSG00000171634","BPTF","GO:0046872(metal ion binding);GO:0005654(nucleoplasm);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0016569(covalent chromatin modification);GO:0005515(protein binding);GO:0070062(extracellular exosome);GO:0000790(nuclear chromatin);GO:0045893(positive regulation of transcription, DNA-templated);GO:0048188(Set1C/COMPASS complex);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0016589(NURF complex);GO:0008134(transcription factor binding);GO:0043565(sequence-specific DNA binding);GO:0007420(brain development);GO:0008094(DNA-dependent ATPase activity);GO:0006338(chromatin remodeling);GO:0001892(embryonic placenta development);GO:0007492(endoderm development);GO:0009611(response to wounding);GO:0009952(anterior/posterior pattern specification);GO:1990090(cellular response to nerve growth factor stimulus);GO:0030425(dendrite);GO:0043005(neuron projection);GO:0044297(cell body);GO:0048471(perinuclear region of cytoplasm)","NA","NA","NA","bromodomain PHD finger transcription factor [Source:HGNC Symbol;Acc:HGNC:3581]",{"v":2.389432,"d":"2.39"},{"v":0.236968,"d":"0.24"},{"v":10.083353026569,"d":"10.08"},{"v":3.33390355420359,"d":"3.33"},{"v":1.20789501194751e-05,"d":"0.00"},{"v":0.000786244292645308,"d":"0.00"},"up","yes"]
[17474,0,"chr1","-",243124428,243255321,"ENST00000366544",19,6805,"ENSG00000143702","CEP170","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005829(cytosol);GO:0005813(centrosome);GO:0005737(cytoplasm);GO:0031965(nuclear membrane);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0005874(microtubule);GO:0005819(spindle);GO:0005814(centriole)","NA","NA","NA","centrosomal protein 170 [Source:HGNC Symbol;Acc:HGNC:28920]",{"v":0.120123,"d":"0.12"},{"v":0.963689,"d":"0.96"},{"v":0.124649134731226,"d":"0.12"},{"v":-3.00405522668533,"d":"-3.00"},{"v":1.23614477185637e-05,"d":"0.00"},{"v":0.0008019945162457,"d":"0.00"},"down","yes"]
[185575,0,"chr8","-",93729356,93741017,"ENST00000399300",3,7269,"ENSG00000183808","RBM12B","GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0005515(protein binding)","NA","NA","NA","RNA binding motif protein 12B [Source:HGNC Symbol;Acc:HGNC:32310]",{"v":1.78011,"d":"1.78"},{"v":0.172144,"d":"0.17"},{"v":10.3408193140626,"d":"10.34"},{"v":3.3702785913243,"d":"3.37"},{"v":1.24566359536283e-05,"d":"0.00"},{"v":0.000805529125001294,"d":"0.00"},"up","yes"]
[76906,0,"chr16","-",89286663,89317075,"ENST00000562275",6,2762,"MSTRG.6242","ANKRD11","GO:0005634(nucleus);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0005886(plasma membrane);GO:0042475(odontogenesis of dentin-containing tooth);GO:0048705(skeletal system morphogenesis);GO:0060325(face morphogenesis);GO:0001701(in utero embryonic development);GO:0001894(tissue homeostasis);GO:0035264(multicellular organism growth);GO:0060323(head morphogenesis);GO:0060348(bone development)","NA","NA","NA","ankyrin repeat domain 11 [Source:HGNC Symbol;Acc:HGNC:21316]",{"v":0.365275,"d":"0.37"},{"v":2.884292,"d":"2.88"},{"v":0.126642864176027,"d":"0.13"},{"v":-2.98116230570027,"d":"-2.98"},{"v":1.25586922488316E-5,"d":"0.00"},{"v":0.000807435160928742,"d":"0.00"},"down","yes"]
[15547,0,"chr1","+",207496157,207640647,"ENST00000367053",39,7469,"MSTRG.1357","CR1","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0002376(immune system process);GO:0045087(innate immune response);GO:0030449(regulation of complement activation);GO:0005886(plasma membrane);GO:0005887(integral component of plasma membrane);GO:0046718(viral entry into host cell);GO:0070062(extracellular exosome);GO:0016032(viral process);GO:0002430(complement receptor mediated signaling pathway);GO:0043312(neutrophil degranulation);GO:0006958(complement activation, classical pathway);GO:0009986(cell surface);GO:0030667(secretory granule membrane);GO:0001618(virus receptor activity);GO:0101003(ficolin-1-rich granule membrane);GO:0045589(regulation of regulatory T cell differentiation);GO:1900005(positive regulation of serine-type endopeptidase activity);GO:1900004(negative regulation of serine-type endopeptidase activity);GO:0001851(complement component C3b binding);GO:0001855(complement component C4b binding);GO:0001861(complement component C4b receptor activity);GO:0004877(complement component C3b receptor activity);GO:0045957(negative regulation of complement activation, alternative pathway);GO:0045959(negative regulation of complement activation, classical pathway)","04640(Hematopoietic cell lineage);04610(Complement and coagulation cascades);05134(Legionellosis);05152(Tuberculosis);05144(Malaria);05140(Leishmaniasis)","NA","NA","complement C3b/C4b receptor 1 (Knops blood group) [Source:HGNC Symbol;Acc:HGNC:2334]",{"v":6.987785,"d":"6.99"},{"v":0.706646,"d":"0.71"},{"v":9.88866419678311,"d":"9.89"},{"v":3.30577564870582,"d":"3.31"},{"v":1.25677193029135E-5,"d":"0.00"},{"v":0.000807435160928742,"d":"0.00"},"up","yes"]
[92369,0,"chr18","-",49488561,49492432,"ENST00000578532",7,684,"MSTRG.7521","RPL17","GO:0003723(RNA binding);GO:0005634(nucleus);GO:0006412(translation);GO:0030529(intracellular ribonucleoprotein complex);GO:0005622(intracellular);GO:0003735(structural constituent of ribosome);GO:0005840(ribosome);GO:0015934(large ribosomal subunit);GO:0005829(cytosol);GO:0005515(protein binding);GO:0006413(translational initiation);GO:0006364(rRNA processing);GO:0000184(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay);GO:0019083(viral transcription);GO:0006614(SRP-dependent cotranslational protein targeting to membrane);GO:0022625(cytosolic large ribosomal subunit)","03010(Ribosome)","K02880","NA","ribosomal protein L17 [Source:HGNC Symbol;Acc:HGNC:10307]",{"v":7.627138,"d":"7.63"},{"v":56.967381,"d":"56.97"},{"v":0.13388605665407,"d":"0.13"},{"v":-2.90092237353406,"d":"-2.90"},{"v":1.28923376589036e-05,"d":"0.00"},{"v":0.000825610283476973,"d":"0.00"},"down","yes"]
[52662,0,"chr14","-",21385486,21456080,"ENST00000557364",38,8137,"MSTRG.4144","CHD8","GO:0005634(nucleus);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0005654(nucleoplasm);GO:0016787(hydrolase activity);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0016569(covalent chromatin modification);GO:0004386(helicase activity);GO:0032508(DNA duplex unwinding);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0043044(ATP-dependent chromatin remodeling);GO:0016055(Wnt signaling pathway);GO:0045893(positive regulation of transcription, DNA-templated);GO:0016817(hydrolase activity, acting on acid anhydrides);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0030178(negative regulation of Wnt signaling pathway);GO:0043234(protein complex);GO:0042393(histone binding);GO:0045892(negative regulation of transcription, DNA-templated);GO:0071339(MLL1 complex);GO:0008013(beta-catenin binding);GO:0007420(brain development);GO:0035064(methylated histone binding);GO:0002039(p53 binding);GO:0060070(canonical Wnt signaling pathway);GO:0008094(DNA-dependent ATPase activity);GO:0090090(negative regulation of canonical Wnt signaling pathway);GO:0003682(chromatin binding);GO:0003678(DNA helicase activity);GO:0045945(positive regulation of transcription from RNA polymerase III promoter);GO:0048565(digestive tract development);GO:0070016(armadillo repeat domain binding);GO:0001701(in utero embryonic development);GO:0043066(negative regulation of apoptotic process);GO:2000270(negative regulation of fibroblast apoptotic process)","04310(Wnt signaling pathway)","NA","NA","chromodomain helicase DNA binding protein 8 [Source:HGNC Symbol;Acc:HGNC:20153]",{"v":11.006539,"d":"11.01"},{"v":1.126524,"d":"1.13"},{"v":9.77035464845844,"d":"9.77"},{"v":3.28841093069787,"d":"3.29"},{"v":1.32979356494515E-5,"d":"0.00"},{"v":0.00084817603394916,"d":"0.00"},"up","yes"]
[47464,"j","chr12","+",120534365,120577594,"MSTRG.3797.4",18,3912,"MSTRG.3797","RNF10","NA","NA","NA","NA","NA",{"v":11.692044,"d":"11.69"},{"v":1.190862,"d":"1.19"},{"v":9.81813509877719,"d":"9.82"},{"v":3.29544901850625,"d":"3.30"},{"v":1.33304399918228E-5,"d":"0.00"},{"v":0.00084817603394916,"d":"0.00"},"up","yes"]
[76751,0,"chr16","-",88696536,88703617,"ENST00000541206",6,2419,"MSTRG.6232","RNF166","GO:0046872(metal ion binding);GO:0005622(intracellular);GO:0061630(ubiquitin protein ligase activity);GO:0000209(protein polyubiquitination);GO:0032436(positive regulation of proteasomal ubiquitin-dependent protein catabolic process);GO:0031624(ubiquitin conjugating enzyme binding)","NA","NA","NA","ring finger protein 166 [Source:HGNC Symbol;Acc:HGNC:28856]",{"v":3.491929,"d":"3.49"},{"v":0.339046,"d":"0.34"},{"v":10.2992779740802,"d":"10.30"},{"v":3.36447129640016,"d":"3.36"},{"v":1.40286337747944E-5,"d":"0.00"},{"v":8.89739119024458E-4,"d":"0.00"},"up","yes"]
[154439,0,"chr5","-",40825262,40835335,"ENST00000274242",4,7686,"MSTRG.12021","RPL37","GO:0003723(RNA binding);GO:0006412(translation);GO:0046872(metal ion binding);GO:0030529(intracellular ribonucleoprotein complex);GO:0005622(intracellular);GO:0003735(structural constituent of ribosome);GO:0005840(ribosome);GO:0005829(cytosol);GO:0019843(rRNA binding);GO:0006413(translational initiation);GO:0006364(rRNA processing);GO:0000184(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay);GO:0019083(viral transcription);GO:0006614(SRP-dependent cotranslational protein targeting to membrane);GO:0022625(cytosolic large ribosomal subunit)","03010(Ribosome)","K02922","NA","ribosomal protein L37 [Source:HGNC Symbol;Acc:HGNC:10347]",{"v":4.977444,"d":"4.98"},{"v":36.200474,"d":"36.20"},{"v":0.137496652668139,"d":"0.14"},{"v":-2.86253159797994,"d":"-2.86"},{"v":1.45057348396516e-05,"d":"0.00"},{"v":0.00091705904475088,"d":"0.00"},"down","yes"]
[199718,0,"chrX","-",120625793,120630150,"ENST00000304661",2,1613,"MSTRG.15434","C1GALT1C1","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005515(protein binding);GO:0070062(extracellular exosome);GO:0000139(Golgi membrane);GO:0016266(O-glycan processing);GO:0006493(protein O-linked glycosylation);GO:0016263(glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity);GO:0016267(O-glycan processing, core 1);GO:0030168(platelet activation);GO:0036344(platelet morphogenesis)","00512(Mucin type O-glycan biosynthesis)","K09653","EC:2.4.1.-","C1GALT1 specific chaperone 1 [Source:HGNC Symbol;Acc:HGNC:24338]",{"v":5.553618,"d":"5.55"},{"v":0.533703,"d":"0.53"},{"v":10.4058212151702,"d":"10.41"},{"v":3.37931892024916,"d":"3.38"},{"v":1.49096724882139e-05,"d":"0.00"},{"v":0.000939594264957887,"d":"0.00"},"up","yes"]
[80044,0,"chr17","-",17246837,17281191,"ENST00000578317",12,1625,"MSTRG.6490","COPS3","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0005515(protein binding);GO:0008180(COP9 signalosome);GO:0043687(post-translational protein modification);GO:0007165(signal transduction);GO:0000338(protein deneddylation);GO:0006283(transcription-coupled nucleotide-excision repair);GO:0006511(ubiquitin-dependent protein catabolic process);GO:0000715(nucleotide-excision repair, DNA damage recognition);GO:0009416(response to light stimulus);GO:0001701(in utero embryonic development)","NA","NA","NA","COP9 signalosome subunit 3 [Source:HGNC Symbol;Acc:HGNC:2239]",{"v":1.111573,"d":"1.11"},{"v":8.294377,"d":"8.29"},{"v":0.134015249126004,"d":"0.13"},{"v":-2.8995309256463,"d":"-2.90"},{"v":1.52741699883685e-05,"d":"0.00"},{"v":0.000957083948046015,"d":"0.00"},"down","yes"]
[50324,0,"chr13","+",49444374,49495003,"ENST00000354234",15,6139,"ENSG00000136169","SETDB2","GO:0005634(nucleus);GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0008168(methyltransferase activity);GO:0016740(transferase activity);GO:0032259(methylation);GO:0016569(covalent chromatin modification);GO:0003677(DNA binding);GO:0051301(cell division);GO:0005694(chromosome);GO:0005515(protein binding);GO:0007049(cell cycle);GO:0007275(multicellular organism development);GO:0018024(histone-lysine N-methyltransferase activity);GO:0034968(histone lysine methylation);GO:0007059(chromosome segregation);GO:0045892(negative regulation of transcription, DNA-templated);GO:0000278(mitotic cell cycle);GO:0046974(histone methyltransferase activity (H3-K9 specific));GO:0001947(heart looping);GO:0070986(left/right axis specification);GO:0051567(histone H3-K9 methylation)","00310(Lysine degradation)","K18494","EC:2.1.1.43","SET domain bifurcated 2 [Source:HGNC Symbol;Acc:HGNC:20263]",{"v":2.147145,"d":"2.15"},{"v":0.215603,"d":"0.22"},{"v":9.95878999828388,"d":"9.96"},{"v":3.31597046422902,"d":"3.32"},{"v":1.52839361018062e-05,"d":"0.00"},{"v":0.000957083948046015,"d":"0.00"},"up","yes"]
[200986,0,"chrX","+",153794639,153798505,"ENST00000370086",6,643,"MSTRG.15491","SSR4","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0070062(extracellular exosome);GO:0005784(Sec61 translocon complex)","04141(Protein processing in endoplasmic reticulum)","K04571","NA","signal sequence receptor subunit 4 [Source:HGNC Symbol;Acc:HGNC:11326]",{"v":4.791041,"d":"4.79"},{"v":35.391781,"d":"35.39"},{"v":0.135371571156591,"d":"0.14"},{"v":-2.88500329879359,"d":"-2.89"},{"v":1.53674139634573e-05,"d":"0.00"},{"v":0.000958637431965307,"d":"0.00"},"down","yes"]
[29725,0,"chr11","+",60455847,60470058,"ENST00000532073",7,2560,"MSTRG.2427","MS4A1","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005887(integral component of plasma membrane);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0005615(extracellular space);GO:0005154(epidermal growth factor receptor binding);GO:0009897(external side of plasma membrane);GO:0070062(extracellular exosome);GO:0042113(B cell activation);GO:0006959(humoral immune response);GO:0042100(B cell proliferation);GO:0023026(MHC class II protein complex binding)","04640(Hematopoietic cell lineage)","NA","NA","membrane spanning 4-domains A1 [Source:HGNC Symbol;Acc:HGNC:7315]",{"v":0.481633,"d":"0.48"},{"v":3.661593,"d":"3.66"},{"v":0.131536465139626,"d":"0.13"},{"v":-2.92646528941309,"d":"-2.93"},{"v":1.5405634898169e-05,"d":"0.00"},{"v":0.000958637431965307,"d":"0.00"},"down","yes"]
[169280,0,"chr6","-",132744196,132763447,"ENST00000525270",8,1608,"MSTRG.13286","VNN2","GO:0016810(hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds);GO:0006807(nitrogen compound metabolic process);GO:0016811(hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides);GO:0016020(membrane);GO:0016787(hydrolase activity);GO:0005886(plasma membrane);GO:0031225(anchored component of membrane);GO:0005576(extracellular region);GO:0006501(C-terminal protein lipidation);GO:0006928(movement of cell or subcellular component);GO:0017159(pantetheine hydrolase activity);GO:0015939(pantothenate metabolic process)","00770(Pantothenate and CoA biosynthesis)","K08069","EC:3.5.1.92","vanin 2 [Source:HGNC Symbol;Acc:HGNC:12706]",{"v":8.106831,"d":"8.11"},{"v":0.816349,"d":"0.82"},{"v":9.93059463538266,"d":"9.93"},{"v":3.31188010766631,"d":"3.31"},{"v":1.55068514262617e-05,"d":"0.00"},{"v":0.000961910896623405,"d":"0.00"},"up","yes"]
[132577,0,"chr22","-",50525755,50529996,"ENST00000487577",9,1751,"MSTRG.10610","TYMP","GO:0016740(transferase activity);GO:0016757(transferase activity, transferring glycosyl groups);GO:0008083(growth factor activity);GO:0008152(metabolic process);GO:0007275(multicellular organism development);GO:0030154(cell differentiation);GO:0006935(chemotaxis);GO:0016763(transferase activity, transferring pentosyl groups);GO:0004645(phosphorylase activity);GO:0006206(pyrimidine nucleobase metabolic process);GO:0006213(pyrimidine nucleoside metabolic process);GO:0005829(cytosol);GO:0009032(thymidine phosphorylase activity);GO:0016154(pyrimidine-nucleoside phosphorylase activity);GO:0043097(pyrimidine nucleoside salvage);GO:0001525(angiogenesis);GO:0042803(protein homodimerization activity);GO:0046135(pyrimidine nucleoside catabolic process);GO:0000002(mitochondrial genome maintenance);GO:0031641(regulation of myelination);GO:0051969(regulation of transmission of nerve impulse);GO:1905333(regulation of gastric motility)","00240(Pyrimidine metabolism);00983(Drug metabolism - other enzymes);05219(Bladder cancer)","NA","NA","thymidine phosphorylase [Source:HGNC Symbol;Acc:HGNC:3148]",{"v":0.487978,"d":"0.49"},{"v":3.795468,"d":"3.80"},{"v":0.128568598128083,"d":"0.13"},{"v":-2.95938977614786,"d":"-2.96"},{"v":1.58895584964302e-05,"d":"0.00"},{"v":0.000982570573523003,"d":"0.00"},"down","yes"]
[117417,0,"chr2","-",190975537,191014168,"ENST00000392322",23,2716,"MSTRG.9305","STAT1","GO:0005634(nucleus);GO:0006355(regulation of transcription, DNA-templated);GO:0007165(signal transduction);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0004871(signal transducer activity);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0005737(cytoplasm);GO:0005730(nucleolus);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0042803(protein homodimerization activity);GO:0005515(protein binding);GO:0006915(apoptotic process);GO:0048471(perinuclear region of cytoplasm);GO:0045893(positive regulation of transcription, DNA-templated);GO:0030425(dendrite);GO:0042802(identical protein binding);GO:0051607(defense response to virus);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0030424(axon);GO:0001047(core promoter binding);GO:0045296(cadherin binding);GO:0071346(cellular response to interferon-gamma);GO:0016032(viral process);GO:0003690(double-stranded DNA binding);GO:0042981(regulation of apoptotic process);GO:0035722(interleukin-12-mediated signaling pathway);GO:0019899(enzyme binding);GO:0000790(nuclear chromatin);GO:0070491(repressing transcription factor binding);GO:0001937(negative regulation of endothelial cell proliferation);GO:0016525(negative regulation of angiogenesis);GO:0060333(interferon-gamma-mediated signaling pathway);GO:0060334(regulation of interferon-gamma-mediated signaling pathway);GO:0043124(negative regulation of I-kappaB kinase/NF-kappaB signaling);GO:0005164(tumor necrosis factor receptor binding);GO:0033209(tumor necrosis factor-mediated signaling pathway);GO:0060337(type I interferon signaling pathway);GO:0048661(positive regulation of smooth muscle cell proliferation);GO:0035456(response to interferon-beta);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:0051591(response to cAMP);GO:0035257(nuclear hormone receptor binding);GO:0002053(positive regulation of mesenchymal cell proliferation);GO:0072162(metanephric mesenchymal cell differentiation);GO:0000983(transcription factor activity, RNA polymerase II core promoter sequence-specific);GO:0034097(response to cytokine);GO:0060338(regulation of type I interferon-mediated signaling pathway);GO:0035458(cellular response to interferon-beta);GO:0045648(positive regulation of erythrocyte differentiation);GO:0000979(RNA polymerase II core promoter sequence-specific DNA binding);GO:0010742(macrophage derived foam cell differentiation);GO:0007259(JAK-STAT cascade);GO:0003340(negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis);GO:0008015(blood circulation);GO:0043434(response to peptide hormone);GO:0046725(negative regulation by virus of viral protein levels in host cell);GO:0061326(renal tubule development);GO:0072136(metanephric mesenchymal cell proliferation involved in metanephros development);GO:0072308(negative regulation of metanephric nephron tubule epithelial cell differentiation)","04630(Jak-STAT signaling pathway);04217(Necroptosis);04620(Toll-like receptor signaling pathway);04621(NOD-like receptor signaling pathway);04658(Th1 and Th2 cell differentiation);04659(Th17 cell differentiation);04062(Chemokine signaling pathway);04917(Prolactin signaling pathway);04919(Thyroid hormone signaling pathway);04380(Osteoclast differentiation);05200(Pathways in cancer);05212(Pancreatic cancer);05321(Inflammatiory bowel disease (IBD));04933(AGE-RAGE signaling pathway in diabetic complications);05152(Tuberculosis);05162(Measles);05164(Influenza A);05161(Hepatitis B);05160(Hepatitis C);05168(Herpes simplex infection);05167(Kaposi's sarcoma-associated herpesvirus infection);05165(Human papillomavirus infection);05145(Toxoplasmosis);05140(Leishmaniasis)","K11220","NA","signal transducer and activator of transcription 1 [Source:HGNC Symbol;Acc:HGNC:11362]",{"v":4.921433,"d":"4.92"},{"v":0.500426,"d":"0.50"},{"v":9.83448701706146,"d":"9.83"},{"v":3.29784980113187,"d":"3.30"},{"v":1.67186421339836e-05,"d":"0.00"},{"v":0.00103061835061454,"d":"0.00"},"up","yes"]
[44091,0,"chr12","+",67648721,67665406,"ENST00000344096",3,8912,"ENSG00000127334","DYRK2","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0004713(protein tyrosine kinase activity);GO:0018108(peptidyl-tyrosine phosphorylation);GO:0005515(protein binding);GO:0006974(cellular response to DNA damage stimulus);GO:0006915(apoptotic process);GO:0000287(magnesium ion binding);GO:0007224(smoothened signaling pathway);GO:1901796(regulation of signal transduction by p53 class mediator);GO:0000151(ubiquitin ligase complex);GO:0004712(protein serine/threonine/tyrosine kinase activity);GO:0042771(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator);GO:0030145(manganese ion binding);GO:0045725(positive regulation of glycogen biosynthetic process);GO:0051534(negative regulation of NFAT protein import into nucleus);GO:0030529(intracellular ribonucleoprotein complex);GO:0016020(membrane);GO:0016021(integral component of membrane)","NA","NA","NA","dual specificity tyrosine phosphorylation regulated kinase 2 [Source:HGNC Symbol;Acc:HGNC:3093]",{"v":0.412433,"d":"0.41"},{"v":2.998217,"d":"3.00"},{"v":0.137559422816961,"d":"0.14"},{"v":-2.86187312727477,"d":"-2.86"},{"v":1.68981519198116E-5,"d":"0.00"},{"v":0.00103844916207836,"d":"0.00"},"down","yes"]
[24871,0,"chr11","-",612583,615650,"ENST00000469048",9,1634,"MSTRG.2089","IRF7","GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0006355(regulation of transcription, DNA-templated);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0000975(regulatory region DNA binding);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0006974(cellular response to DNA damage stimulus);GO:0045893(positive regulation of transcription, DNA-templated);GO:0002376(immune system process);GO:0045087(innate immune response);GO:0051607(defense response to virus);GO:0010008(endosome membrane);GO:0009615(response to virus);GO:0016032(viral process);GO:0032727(positive regulation of interferon-alpha production);GO:0035666(TRIF-dependent toll-like receptor signaling pathway);GO:0006366(transcription from RNA polymerase II promoter);GO:0032728(positive regulation of interferon-beta production);GO:0060333(interferon-gamma-mediated signaling pathway);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0032481(positive regulation of type I interferon production);GO:0060337(type I interferon signaling pathway);GO:0000979(RNA polymerase II core promoter sequence-specific DNA binding);GO:0050776(regulation of immune response);GO:0000982(transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0002819(regulation of adaptive immune response);GO:0034124(regulation of MyD88-dependent toll-like receptor signaling pathway);GO:0039530(MDA-5 signaling pathway);GO:0032608(interferon-beta production);GO:0019043(establishment of viral latency);GO:0032479(regulation of type I interferon production);GO:0032607(interferon-alpha production);GO:0034127(regulation of MyD88-independent toll-like receptor signaling pathway);GO:0045655(regulation of monocyte differentiation);GO:2000110(negative regulation of macrophage apoptotic process);GO:0016064(immunoglobulin mediated immune response);GO:0045351(type I interferon biosynthetic process);GO:0060340(positive regulation of type I interferon-mediated signaling pathway)","04620(Toll-like receptor signaling pathway);04621(NOD-like receptor signaling pathway);04622(RIG-I-like receptor signaling pathway);04623(Cytosolic DNA-sensing pathway);05203(Viral carcinogenesis);05162(Measles);05164(Influenza A);05161(Hepatitis B);05160(Hepatitis C);05168(Herpes simplex infection);05167(Kaposi's sarcoma-associated herpesvirus infection)","NA","NA","interferon regulatory factor 7 [Source:HGNC Symbol;Acc:HGNC:6122]",{"v":0.57499,"d":"0.57"},{"v":4.388436,"d":"4.39"},{"v":0.1310239000865,"d":"0.13"},{"v":-2.93209809693166,"d":"-2.93"},{"v":1.71137152231103e-05,"d":"0.00"},{"v":0.00104844023787897,"d":"0.00"},"down","yes"]
[176711,0,"chr7","+",100088981,100091905,"ENST00000418625",10,1107,"MSTRG.13801","COPS6","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005654(nucleoplasm);GO:0005515(protein binding);GO:0008180(COP9 signalosome);GO:0000338(protein deneddylation);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0043687(post-translational protein modification);GO:0016032(viral process);GO:0006283(transcription-coupled nucleotide-excision repair);GO:0000715(nucleotide-excision repair, DNA damage recognition)","NA","NA","NA","COP9 signalosome subunit 6 [Source:HGNC Symbol;Acc:HGNC:21749]",{"v":1.268156,"d":"1.27"},{"v":9.495591,"d":"9.50"},{"v":0.133552087489868,"d":"0.13"},{"v":-2.90452556865044,"d":"-2.90"},{"v":1.73022141863243e-05,"d":"0.00"},{"v":0.00105389472831949,"d":"0.00"},"down","yes"]
[197054,0,"chrX","-",48893447,48897762,"ENST00000465150",7,964,"MSTRG.15286","TIMM17B","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0006886(intracellular protein transport);GO:0015031(protein transport);GO:0015450(P-P-bond-hydrolysis-driven protein transmembrane transporter activity);GO:0005743(mitochondrial inner membrane);GO:0005739(mitochondrion);GO:0005744(mitochondrial inner membrane presequence translocase complex);GO:0005515(protein binding);GO:0015266(protein channel activity);GO:0006626(protein targeting to mitochondrion);GO:0030150(protein import into mitochondrial matrix);GO:0031305(integral component of mitochondrial inner membrane)","NA","NA","NA","translocase of inner mitochondrial membrane 17B [Source:HGNC Symbol;Acc:HGNC:17310]",{"v":1.80206,"d":"1.80"},{"v":13.354749,"d":"13.35"},{"v":0.13493776633316,"d":"0.13"},{"v":-2.88963390912018,"d":"-2.89"},{"v":1.73092675714491e-05,"d":"0.00"},{"v":0.00105389472831949,"d":"0.00"},"down","yes"]
[109419,0,"chr2","-",46901874,46915868,"ENST00000319466",4,4182,"MSTRG.8673","MCFD2","GO:0006810(transport);GO:0015031(protein transport);GO:0046872(metal ion binding);GO:0005509(calcium ion binding);GO:0005794(Golgi apparatus);GO:0005783(endoplasmic reticulum);GO:0016192(vesicle-mediated transport);GO:0000139(Golgi membrane);GO:0005789(endoplasmic reticulum membrane);GO:0006888(ER to Golgi vesicle-mediated transport);GO:0048208(COPII vesicle coating);GO:0012507(ER to Golgi transport vesicle membrane);GO:0033116(endoplasmic reticulum-Golgi intermediate compartment membrane);GO:0005793(endoplasmic reticulum-Golgi intermediate compartment);GO:0018279(protein N-linked glycosylation via asparagine)","NA","NA","NA","multiple coagulation factor deficiency 2 [Source:HGNC Symbol;Acc:HGNC:18451]",{"v":0.660925,"d":"0.66"},{"v":4.814506,"d":"4.81"},{"v":0.137277843251208,"d":"0.14"},{"v":-2.86482930269505,"d":"-2.86"},{"v":1.742346627112E-5,"d":"0.00"},{"v":1.05759371341387E-3,"d":"0.00"},"down","yes"]
[66135,"j","chr15","+",88635621,88656483,"MSTRG.5390.1",6,1845,"MSTRG.5390","ISG20","NA","NA","NA","NA","NA",{"v":0.495525,"d":"0.50"},{"v":3.825972,"d":"3.83"},{"v":0.129516107279405,"d":"0.13"},{"v":-2.94879656495183,"d":"-2.95"},{"v":1.75409342010177E-5,"d":"0.00"},{"v":0.00106146790816433,"d":"0.00"},"down","yes"]
[150035,0,"chr4","+",108620656,108630412,"ENST00000394668",6,853,"MSTRG.11786","RPL34","GO:0006412(translation);GO:0030529(intracellular ribonucleoprotein complex);GO:0005622(intracellular);GO:0003735(structural constituent of ribosome);GO:0005840(ribosome);GO:0005829(cytosol);GO:0045296(cadherin binding);GO:0070062(extracellular exosome);GO:0042254(ribosome biogenesis);GO:0006413(translational initiation);GO:0003723(RNA binding);GO:0006364(rRNA processing);GO:0000184(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay);GO:0019083(viral transcription);GO:0006614(SRP-dependent cotranslational protein targeting to membrane);GO:0022625(cytosolic large ribosomal subunit);GO:0005739(mitochondrion)","03010(Ribosome)","K02915","NA","ribosomal protein L34 [Source:HGNC Symbol;Acc:HGNC:10340]",{"v":28.062405,"d":"28.06"},{"v":198.730011,"d":"198.73"},{"v":0.141208692430455,"d":"0.14"},{"v":-2.82409919508618,"d":"-2.82"},{"v":1.81080122152988E-5,"d":"0.00"},{"v":0.00109014185027619,"d":"0.00"},"down","yes"]
[26899,0,"chr11","-",14504913,14520363,"ENST00000530457",10,1527,"MSTRG.2270","PSMA1","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005654(nucleoplasm);GO:0016787(hydrolase activity);GO:0005813(centrosome);GO:0005515(protein binding);GO:0008233(peptidase activity);GO:0006508(proteolysis);GO:0000502(proteasome complex);GO:0006511(ubiquitin-dependent protein catabolic process);GO:0002376(immune system process);GO:0004175(endopeptidase activity);GO:0004298(threonine-type endopeptidase activity);GO:0051603(proteolysis involved in cellular protein catabolic process);GO:0005839(proteasome core complex);GO:0019773(proteasome core complex, alpha-subunit complex);GO:0038095(Fc-epsilon receptor signaling pathway);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0000165(MAPK cascade);GO:0000209(protein polyubiquitination);GO:0002223(stimulatory C-type lectin receptor signaling pathway);GO:0002479(antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent);GO:0006521(regulation of cellular amino acid metabolic process);GO:0010972(negative regulation of G2/M transition of mitotic cell cycle);GO:0016579(protein deubiquitination);GO:0031145(anaphase-promoting complex-dependent catabolic process);GO:0031146(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process);GO:0033209(tumor necrosis factor-mediated signaling pathway);GO:0038061(NIK/NF-kappaB signaling);GO:0043161(proteasome-mediated ubiquitin-dependent protein catabolic process);GO:0043488(regulation of mRNA stability);GO:0043687(post-translational protein modification);GO:0050852(T cell receptor signaling pathway);GO:0051437(positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition);GO:0055085(transmembrane transport);GO:0060071(Wnt signaling pathway, planar cell polarity pathway);GO:0061418(regulation of transcription from RNA polymerase II promoter in response to hypoxia);GO:0090090(negative regulation of canonical Wnt signaling pathway);GO:0090263(positive regulation of canonical Wnt signaling pathway);GO:1902036(regulation of hematopoietic stem cell differentiation);GO:0051436(negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle);GO:0003723(RNA binding);GO:0005844(polysome)","03050(Proteasome)","NA","NA","proteasome subunit alpha 1 [Source:HGNC Symbol;Acc:HGNC:9530]",{"v":3.006428,"d":"3.01"},{"v":21.572323,"d":"21.57"},{"v":0.139365055863478,"d":"0.14"},{"v":-2.84305922702581,"d":"-2.84"},{"v":1.81550623381252E-5,"d":"0.00"},{"v":0.00109014185027619,"d":"0.00"},"down","yes"]
[11508,0,"chr1","+",155002657,155018522,"ENST00000368426",4,3594,"MSTRG.1027","ZBTB7B","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0005654(nucleoplasm);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0007275(multicellular organism development);GO:0030154(cell differentiation);GO:0006366(transcription from RNA polymerase II promoter);GO:0007398(ectoderm development);GO:0010628(positive regulation of gene expression);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:0001077(transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0042803(protein homodimerization activity);GO:0043370(regulation of CD4-positive, alpha-beta T cell differentiation);GO:0043376(regulation of CD8-positive, alpha-beta T cell differentiation);GO:0045944(positive regulation of transcription from RNA polymerase II promoter)","NA","NA","NA","zinc finger and BTB domain containing 7B [Source:HGNC Symbol;Acc:HGNC:18668]",{"v":7.433717,"d":"7.43"},{"v":0.778697,"d":"0.78"},{"v":9.54635371652902,"d":"9.55"},{"v":3.25494979287746,"d":"3.25"},{"v":1.81800490494816e-05,"d":"0.00"},{"v":0.00109014185027619,"d":"0.00"},"up","yes"]
[104752,0,"chr19","-",51745172,51751893,"ENST00000595042",3,1965,"MSTRG.8382","FPR1","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0004930(G-protein coupled receptor activity);GO:0007186(G-protein coupled receptor signaling pathway);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0004871(signal transducer activity);GO:0007165(signal transduction);GO:0004982(N-formyl peptide receptor activity);GO:0006935(chemotaxis);GO:0060326(cell chemotaxis);GO:0005887(integral component of plasma membrane);GO:0006954(inflammatory response);GO:0043312(neutrophil degranulation);GO:0005622(intracellular);GO:0030667(secretory granule membrane);GO:0035577(azurophil granule membrane);GO:0101003(ficolin-1-rich granule membrane);GO:0007188(adenylate cyclase-modulating G-protein coupled receptor signaling pathway);GO:0004875(complement receptor activity);GO:0002430(complement receptor mediated signaling pathway);GO:0007204(positive regulation of cytosolic calcium ion concentration);GO:0050900(leukocyte migration);GO:0007263(nitric oxide mediated signal transduction);GO:0000187(activation of MAPK activity);GO:0005124(scavenger receptor binding);GO:0050786(RAGE receptor binding);GO:0007200(phospholipase C-activating G-protein coupled receptor signaling pathway)","04015(Rap1 signaling pathway);04080(Neuroactive ligand-receptor interaction);05150(Staphylococcus aureus infection)","K04172","NA","formyl peptide receptor 1 [Source:HGNC Symbol;Acc:HGNC:3826]",{"v":10.892113,"d":"10.89"},{"v":76.983177,"d":"76.98"},{"v":0.141486925123914,"d":"0.14"},{"v":-2.82125935582621,"d":"-2.82"},{"v":1.84468125360358e-05,"d":"0.00"},{"v":0.00110279615245643,"d":"0.00"},"down","yes"]
[105413,0,"chr19","+",54200742,54207647,"ENST00000302907",5,829,"MSTRG.8410","RPS9","GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0006412(translation);GO:0030529(intracellular ribonucleoprotein complex);GO:0005622(intracellular);GO:0003735(structural constituent of ribosome);GO:0005840(ribosome);GO:0015935(small ribosomal subunit);GO:0005515(protein binding);GO:0022627(cytosolic small ribosomal subunit);GO:0019843(rRNA binding);GO:0005730(nucleolus);GO:0005925(focal adhesion);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0008284(positive regulation of cell proliferation);GO:0006413(translational initiation);GO:0006364(rRNA processing);GO:0000184(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay);GO:0019083(viral transcription);GO:0006614(SRP-dependent cotranslational protein targeting to membrane);GO:0045182(translation regulator activity);GO:0045903(positive regulation of translational fidelity)","03010(Ribosome)","K02997","NA","ribosomal protein S9 [Source:HGNC Symbol;Acc:HGNC:10442]",{"v":191.304977,"d":"191.30"},{"v":20.531233,"d":"20.53"},{"v":9.31775393129093,"d":"9.32"},{"v":3.21998223141291,"d":"3.22"},{"v":1.86786701925659e-05,"d":"0.00"},{"v":0.00111329375232077,"d":"0.00"},"up","yes"]
[10931,0,"chr1","+",151612082,151699074,"ENST00000458013",12,6403,"MSTRG.958","SNX27","GO:0006810(transport);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0006886(intracellular protein transport);GO:0015031(protein transport);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0007165(signal transduction);GO:0035091(phosphatidylinositol binding);GO:0032266(phosphatidylinositol-3-phosphate binding);GO:0016197(endosomal transport);GO:0008289(lipid binding);GO:0005515(protein binding);GO:0005768(endosome);GO:0005769(early endosome);GO:1990126(retrograde transport, endosome to plasma membrane);GO:0031901(early endosome membrane);GO:0071203(WASH complex);GO:0001772(immunological synapse);GO:0030904(retromer complex);GO:0001770(establishment of natural killer cell polarity);GO:0008333(endosome to lysosome transport)","NA","NA","NA","sorting nexin family member 27 [Source:HGNC Symbol;Acc:HGNC:20073]",{"v":9.537972,"d":"9.54"},{"v":1.017911,"d":"1.02"},{"v":9.37014336223894,"d":"9.37"},{"v":3.22807112114049,"d":"3.23"},{"v":1.90535741199403e-05,"d":"0.00"},{"v":0.0011322286026588,"d":"0.00"},"up","yes"]
[35626,0,"chr11","+",117986737,118003037,"ENST00000529924",6,6711,"MSTRG.2870","IL10RA","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005515(protein binding);GO:0019221(cytokine-mediated signaling pathway);GO:0007165(signal transduction);GO:0005886(plasma membrane);GO:0004920(interleukin-10 receptor activity);GO:0004871(signal transducer activity);GO:0004872(receptor activity);GO:0019969(interleukin-10 binding);GO:0032496(response to lipopolysaccharide);GO:0050807(regulation of synapse organization)","04630(Jak-STAT signaling pathway);04060(Cytokine-cytokine receptor interaction);05152(Tuberculosis);05169(Epstein-Barr virus infection);05145(Toxoplasmosis)","NA","NA","interleukin 10 receptor subunit alpha [Source:HGNC Symbol;Acc:HGNC:5964]",{"v":17.090038,"d":"17.09"},{"v":1.84047,"d":"1.84"},{"v":9.28569224165566,"d":"9.29"},{"v":3.21500946604404,"d":"3.22"},{"v":1.94240797298776E-5,"d":"0.00"},{"v":0.00114800270323803,"d":"0.00"},"up","yes"]
[56312,0,"chr14","+",69767124,69771991,"ENST00000557154",8,1500,"MSTRG.4509","SRSF5","GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0006397(mRNA processing);GO:0008380(RNA splicing);GO:0005634(nucleus);GO:0016607(nuclear speck);GO:0005730(nucleolus);GO:0005829(cytosol);GO:0043422(protein kinase B binding);GO:0001889(liver development);GO:0032868(response to insulin);GO:0032869(cellular response to insulin stimulus);GO:0033120(positive regulation of RNA splicing);GO:0051726(regulation of cell cycle);GO:0097421(liver regeneration);GO:0005654(nucleoplasm);GO:0005515(protein binding);GO:0006369(termination of RNA polymerase II transcription);GO:0006405(RNA export from nucleus);GO:0031124(mRNA 3'-end processing);GO:0000398(mRNA splicing, via spliceosome);GO:0006406(mRNA export from nucleus);GO:0006376(mRNA splice site selection)","03040(Spliceosome);05168(Herpes simplex infection)","K12893","NA","serine and arginine rich splicing factor 5 [Source:HGNC Symbol;Acc:HGNC:10787]",{"v":2.71887,"d":"2.72"},{"v":19.384058,"d":"19.38"},{"v":0.140263199790261,"d":"0.14"},{"v":-2.83379154953731,"d":"-2.83"},{"v":1.94350568821882e-05,"d":"0.00"},{"v":0.00114800270323803,"d":"0.00"},"down","yes"]
[143477,0,"chr3","+",184314495,184335353,"ENST00000346169",33,5516,"MSTRG.11394","EIF4G1","GO:0003723(RNA binding);GO:0016020(membrane);GO:0003743(translation initiation factor activity);GO:0006412(translation);GO:0006413(translational initiation);GO:0006446(regulation of translational initiation);GO:0005515(protein binding);GO:0008190(eukaryotic initiation factor 4E binding);GO:0005829(cytosol);GO:0045296(cadherin binding);GO:0043488(regulation of mRNA stability);GO:0000289(nuclear-transcribed mRNA poly(A) tail shortening);GO:0006417(regulation of translation);GO:0016032(viral process);GO:0010507(negative regulation of autophagy);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0008135(translation factor activity, RNA binding);GO:0007005(mitochondrion organization);GO:0005524(ATP binding);GO:0000184(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay);GO:0016281(eukaryotic translation initiation factor 4F complex);GO:1901215(negative regulation of neuron death);GO:0033138(positive regulation of peptidyl-serine phosphorylation);GO:0008284(positive regulation of cell proliferation);GO:1905606(regulation of presynapse assembly);GO:0010801(negative regulation of peptidyl-threonine phosphorylation);GO:0030307(positive regulation of cell growth);GO:0034645(cellular macromolecule biosynthetic process);GO:0022627(cytosolic small ribosomal subunit);GO:0003729(mRNA binding);GO:0031369(translation initiation factor binding);GO:0032947(protein complex scaffold);GO:0002191(cap-dependent translational initiation);GO:0032270(positive regulation of cellular protein metabolic process);GO:0032502(developmental process);GO:0060964(regulation of gene silencing by miRNA);GO:0080135(regulation of cellular response to stress);GO:1900087(positive regulation of G1/S transition of mitotic cell cycle);GO:1905537(positive regulation of eukaryotic translation initiation factor 4F complex assembly);GO:1905612(positive regulation of mRNA cap binding);GO:1905618(positive regulation of miRNA mediated inhibition of translation);GO:1905696(regulation of polysome binding);GO:2000507(positive regulation of energy homeostasis);GO:0005844(polysome);GO:0001662(behavioral fear response);GO:0045666(positive regulation of neuron differentiation)","03013(RNA transport);05416(Viral myocarditis)","K03260","NA","eukaryotic translation initiation factor 4 gamma 1 [Source:HGNC Symbol;Acc:HGNC:3296]",{"v":18.107367,"d":"18.11"},{"v":1.949312,"d":"1.95"},{"v":9.28910661812988,"d":"9.29"},{"v":3.21553985176716,"d":"3.22"},{"v":1.96558649365718e-05,"d":"0.00"},{"v":1.15573585072859E-3,"d":"0.00"},"up","yes"]
[12944,"j","chr1","+",161505430,161527118,"MSTRG.1158.4",8,9831,"MSTRG.1158","FCGR2A","NA","NA","NA","NA","NA",{"v":20.508038,"d":"20.51"},{"v":2.216722,"d":"2.22"},{"v":9.2515155260786,"d":"9.25"},{"v":3.20968971837094,"d":"3.21"},{"v":1.97179798555767E-5,"d":"0.00"},{"v":1.15573585072859E-3,"d":"0.00"},"up","yes"]
[98494,"j","chr19","+",18110137,18150640,"MSTRG.7984.5",28,5209,"MSTRG.7984","MAST3","NA","NA","NA","NA","NA",{"v":3.071435,"d":"3.07"},{"v":0.319318,"d":"0.32"},{"v":9.61873430248217,"d":"9.62"},{"v":3.26584706700294,"d":"3.27"},{"v":1.97411925180039e-05,"d":"0.00"},{"v":1.15573585072859E-3,"d":"0.00"},"up","yes"]
[66504,"j","chr15","+",90902860,90922733,"MSTRG.5438.6",24,6735,"MSTRG.5438","MAN2A2","NA","NA","NA","NA","NA",{"v":8.727767,"d":"8.73"},{"v":0.936025,"d":"0.94"},{"v":9.32428834699928,"d":"9.32"},{"v":3.22099361947682,"d":"3.22"},{"v":1.98116473281864e-05,"d":"0.00"},{"v":1.15643916616564E-3,"d":"0.00"},"up","yes"]
[89930,0,"chr17","+",82458712,82488259,"ENST00000577812",10,2598,"MSTRG.7368","NARF","GO:0005634(nucleus);GO:0005730(nucleolus);GO:0055114(oxidation-reduction process);GO:0003954(NADH dehydrogenase activity);GO:0005521(lamin binding);GO:0005638(lamin filament);GO:0005652(nuclear lamina);GO:0031981(nuclear lumen)","NA","NA","NA","nuclear prelamin A recognition factor [Source:HGNC Symbol;Acc:HGNC:29916]",{"v":1.664995,"d":"1.66"},{"v":11.777947,"d":"11.78"},{"v":0.141365468871612,"d":"0.14"},{"v":-2.82249833663295,"d":"-2.82"},{"v":2.0044332332592e-05,"d":"0.00"},{"v":0.00116389722225886,"d":"0.00"},"down","yes"]
[154540,"u","chr5","-",42985082,42993323,"MSTRG.12023.1",2,3066,"MSTRG.12023",".","NA","NA","NA","NA","NA",{"v":7.775853,"d":"7.78"},{"v":0.821722,"d":"0.82"},{"v":9.46287552237862,"d":"9.46"},{"v":3.2422786477825,"d":"3.24"},{"v":2.00570523948995E-5,"d":"0.00"},{"v":0.00116389722225886,"d":"0.00"},"up","yes"]
[10324,"j","chr1","-",148531490,148560644,"MSTRG.886.3",14,3284,"MSTRG.886","NBPF14","NA","NA","NA","NA","NA",{"v":13.691498,"d":"13.69"},{"v":1.477811,"d":"1.48"},{"v":9.26471517670392,"d":"9.26"},{"v":3.21174662444757,"d":"3.21"},{"v":2.11353891195079E-5,"d":"0.00"},{"v":1.22217578741287E-3,"d":"0.00"},"up","yes"]
[200995,0,"chrX","-",153802168,153830548,"ENST00000393758",8,3763,"ENSG00000067840","PDZD4","GO:0005737(cytoplasm);GO:0005938(cell cortex);GO:0005515(protein binding)","NA","NA","NA","PDZ domain containing 4 [Source:HGNC Symbol;Acc:HGNC:21167]",{"v":0.383329,"d":"0.38"},{"v":2.799342,"d":"2.80"},{"v":0.136935394103329,"d":"0.14"},{"v":-2.86843270236321,"d":"-2.87"},{"v":2.11848744230147e-05,"d":"0.00"},{"v":1.22217578741287E-3,"d":"0.00"},"down","yes"]
[144644,0,"chr3","-",196347662,196432474,"ENST00000296328",11,10568,"MSTRG.11451","UBXN7","GO:0005654(nucleoplasm);GO:0016604(nuclear body);GO:0005634(nucleus);GO:0005515(protein binding);GO:0005829(cytosol);GO:0043687(post-translational protein modification);GO:0031625(ubiquitin protein ligase binding);GO:0008134(transcription factor binding);GO:0043130(ubiquitin binding);GO:0034098(VCP-NPL4-UFD1 AAA ATPase complex)","NA","NA","NA","UBX domain protein 7 [Source:HGNC Symbol;Acc:HGNC:29119]",{"v":6.241701,"d":"6.24"},{"v":0.677436,"d":"0.68"},{"v":9.21371317733336,"d":"9.21"},{"v":3.20378268757969,"d":"3.20"},{"v":2.15370523990104e-05,"d":"0.00"},{"v":0.0012362856976383,"d":"0.00"},"up","yes"]
[27229,0,"chr11","+",18396278,18407847,"ENST00000379412",8,1922,"MSTRG.2293","LDHA","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0003824(catalytic activity);GO:0006096(glycolytic process);GO:0005975(carbohydrate metabolic process);GO:0016616(oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor);GO:0005515(protein binding);GO:0019752(carboxylic acid metabolic process);GO:0004459(L-lactate dehydrogenase activity);GO:0005829(cytosol);GO:0045296(cadherin binding);GO:0070062(extracellular exosome);GO:0006090(pyruvate metabolic process);GO:0016021(integral component of membrane);GO:0004457(lactate dehydrogenase activity);GO:0019900(kinase binding);GO:0042802(identical protein binding);GO:0051287(NAD binding);GO:0001666(response to hypoxia);GO:0006089(lactate metabolic process);GO:0007584(response to nutrient);GO:0009749(response to glucose);GO:0014070(response to organic cyclic compound);GO:0019674(NAD metabolic process);GO:0042493(response to drug);GO:0042542(response to hydrogen peroxide);GO:0043065(positive regulation of apoptotic process);GO:0043627(response to estrogen);GO:0048569(post-embryonic animal organ development);GO:0051591(response to cAMP)","00010(Glycolysis / Gluconeogenesis);00620(Pyruvate metabolism);00640(Propanoate metabolism);00270(Cysteine and methionine metabolism);04066(HIF-1 signaling pathway);04922(Glucagon signaling pathway);05230(Central carbon metabolism in cancer)","NA","NA","lactate dehydrogenase A [Source:HGNC Symbol;Acc:HGNC:6535]",{"v":0.477915,"d":"0.48"},{"v":3.577022,"d":"3.58"},{"v":0.13360695013897,"d":"0.13"},{"v":-2.90393303714857,"d":"-2.90"},{"v":2.1554404977017E-5,"d":"0.00"},{"v":0.0012362856976383,"d":"0.00"},"down","yes"]
[151018,0,"chr4","-",139716753,140154184,"ENST00000509479",5,6844,"MSTRG.11839","MAML3","GO:0005634(nucleus);GO:0016607(nuclear speck);GO:0003713(transcription coactivator activity);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0007219(Notch signaling pathway);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0005654(nucleoplasm);GO:0006367(transcription initiation from RNA polymerase II promoter);GO:0007221(positive regulation of transcription of Notch receptor target)","04330(Notch signaling pathway);04658(Th1 and Th2 cell differentiation);05165(Human papillomavirus infection)","K06061","NA","mastermind like transcriptional coactivator 3 [Source:HGNC Symbol;Acc:HGNC:16272]",{"v":3.559813,"d":"3.56"},{"v":0.381672,"d":"0.38"},{"v":9.32689062860257,"d":"9.33"},{"v":3.22139619979556,"d":"3.22"},{"v":2.17631148812803e-05,"d":"0.00"},{"v":0.00124201816210755,"d":"0.00"},"up","yes"]
[173237,0,"chr7","-",36855551,37449223,"ENST00000448602",22,2621,"MSTRG.13575","ELMO1","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005886(plasma membrane);GO:0043547(positive regulation of GTPase activity);GO:0030036(actin cytoskeleton organization);GO:0005515(protein binding);GO:0006915(apoptotic process);GO:0016477(cell migration);GO:0038096(Fc-gamma receptor signaling pathway involved in phagocytosis);GO:0006909(phagocytosis);GO:0005829(cytosol);GO:0017124(SH3 domain binding);GO:0048010(vascular endothelial growth factor receptor signaling pathway);GO:0050690(regulation of defense response to virus by virus);GO:0048870(cell motility);GO:0006911(phagocytosis, engulfment);GO:0016601(Rac protein signal transduction);GO:0005085(guanyl-nucleotide exchange factor activity);GO:0032045(guanyl-nucleotide exchange factor complex);GO:0030029(actin filament-based process)","04062(Chemokine signaling pathway);05131(Shigellosis);05100(Bacterial invasion of epithelial cells)","K12366","NA","engulfment and cell motility 1 [Source:HGNC Symbol;Acc:HGNC:16286]",{"v":0.459138,"d":"0.46"},{"v":3.385754,"d":"3.39"},{"v":0.135608789061462,"d":"0.14"},{"v":-2.88247740959548,"d":"-2.88"},{"v":2.17798818602851e-05,"d":"0.00"},{"v":0.00124201816210755,"d":"0.00"},"down","yes"]
[57082,0,"chr14","+",76762189,76783015,"ENST00000167106",7,5728,"ENSG00000071246","VASH1","GO:0005737(cytoplasm);GO:0005783(endoplasmic reticulum);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0007049(cell cycle);GO:0005615(extracellular space);GO:0045765(regulation of angiogenesis);GO:0016525(negative regulation of angiogenesis);GO:0007050(cell cycle arrest);GO:0001937(negative regulation of endothelial cell proliferation);GO:0009611(response to wounding);GO:0043537(negative regulation of blood vessel endothelial cell migration);GO:0001525(angiogenesis);GO:0010596(negative regulation of endothelial cell migration);GO:0045177(apical part of cell);GO:0060674(placenta blood vessel development);GO:0060716(labyrinthine layer blood vessel development);GO:1901491(negative regulation of lymphangiogenesis);GO:2000772(regulation of cellular senescence)","NA","NA","NA","vasohibin 1 [Source:HGNC Symbol;Acc:HGNC:19964]",{"v":2.984994,"d":"2.98"},{"v":0.31764,"d":"0.32"},{"v":9.39741216471477,"d":"9.40"},{"v":3.23226352581789,"d":"3.23"},{"v":2.19286773869057E-5,"d":"0.00"},{"v":0.00124690996589681,"d":"0.00"},"up","yes"]
[105422,0,"chr19","+",54200879,54207644,"ENST00000495002",5,956,"MSTRG.8410","RPS9","GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0006412(translation);GO:0030529(intracellular ribonucleoprotein complex);GO:0005622(intracellular);GO:0003735(structural constituent of ribosome);GO:0005840(ribosome);GO:0015935(small ribosomal subunit);GO:0005515(protein binding);GO:0022627(cytosolic small ribosomal subunit);GO:0019843(rRNA binding);GO:0005730(nucleolus);GO:0005925(focal adhesion);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0008284(positive regulation of cell proliferation);GO:0006413(translational initiation);GO:0006364(rRNA processing);GO:0000184(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay);GO:0019083(viral transcription);GO:0006614(SRP-dependent cotranslational protein targeting to membrane);GO:0045182(translation regulator activity);GO:0045903(positive regulation of translational fidelity)","03010(Ribosome)","NA","NA","ribosomal protein S9 [Source:HGNC Symbol;Acc:HGNC:10442]",{"v":1.99355,"d":"1.99"},{"v":14.253487,"d":"14.25"},{"v":0.139864020642808,"d":"0.14"},{"v":-2.83790321112714,"d":"-2.84"},{"v":2.20696817738681e-05,"d":"0.00"},{"v":0.00124728633716911,"d":"0.00"},"down","yes"]
[11129,0,"chr1","-",153543613,153545063,"ENST00000368715",3,573,"MSTRG.978","S100A4","GO:0003723(RNA binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0005509(calcium ion binding);GO:0005515(protein binding);GO:0048471(perinuclear region of cytoplasm);GO:0005615(extracellular space);GO:0046914(transition metal ion binding);GO:0070062(extracellular exosome);GO:0043123(positive regulation of I-kappaB kinase/NF-kappaB signaling);GO:0050786(RAGE receptor binding);GO:0001837(epithelial to mesenchymal transition);GO:0003779(actin binding);GO:0042802(identical protein binding);GO:0048306(calcium-dependent protein binding);GO:0043005(neuron projection)","NA","NA","NA","S100 calcium binding protein A4 [Source:HGNC Symbol;Acc:HGNC:10494]",{"v":1.691117,"d":"1.69"},{"v":12.456968,"d":"12.46"},{"v":0.135756710621718,"d":"0.14"},{"v":-2.88090458089906,"d":"-2.88"},{"v":2.20948341549501e-05,"d":"0.00"},{"v":0.00124728633716911,"d":"0.00"},"down","yes"]
[84980,0,"chr17","+",48048363,48061487,"ENST00000585291",6,4390,"MSTRG.6959","NFE2L1","GO:0005634(nucleus);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005829(cytosol);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005515(protein binding);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0005737(cytoplasm);GO:0034599(cellular response to oxidative stress);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0006954(inflammatory response);GO:0006366(transcription from RNA polymerase II promoter);GO:0045893(positive regulation of transcription, DNA-templated);GO:0009653(anatomical structure morphogenesis);GO:0000976(transcription regulatory region sequence-specific DNA binding);GO:0003712(transcription cofactor activity);GO:0006783(heme biosynthetic process);GO:0000980(RNA polymerase II distal enhancer sequence-specific DNA binding);GO:0001190(transcriptional activator activity, RNA polymerase II transcription factor binding);GO:0001205(transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding);GO:0019904(protein domain specific binding);GO:0032403(protein complex binding);GO:0030218(erythrocyte differentiation);GO:0043234(protein complex)","NA","NA","NA","nuclear factor, erythroid 2 like 1 [Source:HGNC Symbol;Acc:HGNC:7781]",{"v":2.815814,"d":"2.82"},{"v":0.294867,"d":"0.29"},{"v":9.54943754302787,"d":"9.55"},{"v":3.25541576165299,"d":"3.26"},{"v":2.21243937915078e-05,"d":"0.00"},{"v":0.00124728633716911,"d":"0.00"},"up","yes"]
[156640,0,"chr5","-",90515611,90529561,"ENST00000500869",4,3863,"MSTRG.12195","LYSMD3","GO:0016020(membrane);GO:0016021(integral component of membrane)","NA","NA","NA","LysM domain containing 3 [Source:HGNC Symbol;Acc:HGNC:26969]",{"v":0.25249,"d":"0.25"},{"v":1.842372,"d":"1.84"},{"v":0.137046155716652,"d":"0.14"},{"v":-2.86726623521188,"d":"-2.87"},{"v":2.23920878101679e-05,"d":"0.00"},{"v":1.25879157269205E-3,"d":"0.00"},"down","yes"]
[132809,0,"chr3","+",4493350,4847506,"ENST00000357086",59,9762,"ENSG00000150995","ITPR1","GO:0006810(transport);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0055085(transmembrane transport);GO:0005216(ion channel activity);GO:0006811(ion transport);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005515(protein binding);GO:0007165(signal transduction);GO:0006915(apoptotic process);GO:0006816(calcium ion transport);GO:0070588(calcium ion transmembrane transport);GO:0048471(perinuclear region of cytoplasm);GO:0065009(regulation of molecular function);GO:0031410(cytoplasmic vesicle);GO:0005262(calcium channel activity);GO:0035091(phosphatidylinositol binding);GO:0005886(plasma membrane);GO:0005509(calcium ion binding);GO:0005220(inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity);GO:0048016(inositol phosphate-mediated signaling);GO:1903779(regulation of cardiac conduction);GO:0030168(platelet activation);GO:0050796(regulation of insulin secretion);GO:0070059(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress);GO:0031095(platelet dense tubular network membrane);GO:0030658(transport vesicle membrane);GO:0015278(calcium-release channel activity);GO:0051209(release of sequestered calcium ion into cytosol);GO:0010506(regulation of autophagy);GO:0001666(response to hypoxia);GO:0031094(platelet dense tubular network);GO:0015085(calcium ion transmembrane transporter activity);GO:0019855(calcium channel inhibitor activity);GO:0050849(negative regulation of calcium-mediated signaling);GO:0031088(platelet dense granule membrane);GO:0009791(post-embryonic development);GO:0032469(endoplasmic reticulum calcium ion homeostasis);GO:0042045(epithelial fluid transport);GO:0050882(voluntary musculoskeletal movement);GO:0005635(nuclear envelope);GO:0005637(nuclear inner membrane);GO:0005730(nucleolus);GO:0005955(calcineurin complex);GO:0014069(postsynaptic density);GO:0016529(sarcoplasmic reticulum);GO:0043234(protein complex);GO:0034220(ion transmembrane transport)","04371(Apelin signaling pathway);04020(Calcium signaling pathway);04070(Phosphatidylinositol signaling system);04022(cGMP - PKG signaling pathway);04140(Autophagy - animal);04114(Oocyte meiosis);04210(Apoptosis);04218(Cellular senescence);04540(Gap junction);04611(Platelet activation);04621(NOD-like receptor signaling pathway);04922(Glucagon signaling pathway);04912(GnRH signaling pathway);04915(Estrogen signaling pathway);04921(Oxytocin signaling pathway);04918(Thyroid hormone synthesis);04924(Renin secretion);04925(Aldosterone synthesis and secretion);04927(Cortisol synthesis and secretion);04270(Vascular smooth muscle contraction);04970(Salivary secretion);04971(Gastric acid secretion);04972(Pancreatic secretion);04724(Glutamatergic synapse);04725(Cholinergic synapse);04728(Dopaminergic synapse);04726(Serotonergic synapse);04720(Long-term potentiation);04730(Long-term depression);04723(Retrograde endocannabinoid signaling);04750(Inflammatory mediator regulation of TRP channels);04713(Circadian entrainment);05205(Proteoglycans in cancer);05010(Alzheimer's disease);05016(Huntington's disease);05167(Kaposi's sarcoma-associated herpesvirus infection)","K04958","NA","inositol 1,4,5-trisphosphate receptor type 1 [Source:HGNC Symbol;Acc:HGNC:6180]",{"v":5.273848,"d":"5.27"},{"v":0.575089,"d":"0.58"},{"v":9.17049013283162,"d":"9.17"},{"v":3.19699884323241,"d":"3.20"},{"v":2.29556939837992e-05,"d":"0.00"},{"v":0.00128681946898419,"d":"0.00"},"up","yes"]
[175860,"j","chr7","-",88270933,88306895,"MSTRG.13775.2",6,10050,"MSTRG.13775","STEAP4","NA","NA","NA","NA","NA",{"v":9.693872,"d":"9.69"},{"v":1.064389,"d":"1.06"},{"v":9.10745225664677,"d":"9.11"},{"v":3.18704752704964,"d":"3.19"},{"v":2.31261436842355e-05,"d":"0.00"},{"v":0.00129271223509506,"d":"0.00"},"up","yes"]
[161262,"j","chr5","+",175658056,175710766,"MSTRG.12548.3",5,5068,"MSTRG.12548","HRH2","NA","NA","NA","NA","NA",{"v":2.418653,"d":"2.42"},{"v":0.254891,"d":"0.25"},{"v":9.48896979493195,"d":"9.49"},{"v":3.24625146423046,"d":"3.25"},{"v":2.35479318674193e-05,"d":"0.00"},{"v":0.00131258162195069,"d":"0.00"},"up","yes"]
[105527,"j","chr19","+",54449187,54462037,"MSTRG.8421.4",15,5935,"MSTRG.8421","LENG8","NA","NA","NA","NA","NA",{"v":3.512057,"d":"3.51"},{"v":0.378435,"d":"0.38"},{"v":9.28047617160146,"d":"9.28"},{"v":3.21419883043732,"d":"3.21"},{"v":2.36577404271007e-05,"d":"0.00"},{"v":1.31499822351536E-3,"d":"0.00"},"up","yes"]
[71820,0,"chr16","+",30184748,30187083,"ENST00000569970",5,714,"MSTRG.5828","CORO1A","GO:0051015(actin filament binding);GO:0001845(phagolysosome assembly);GO:0030595(leukocyte chemotaxis);GO:0003723(RNA binding);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005829(cytosol);GO:0003779(actin binding);GO:0042803(protein homodimerization activity);GO:0005886(plasma membrane);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0031410(cytoplasmic vesicle);GO:0008092(cytoskeletal protein binding);GO:0042802(identical protein binding);GO:0006816(calcium ion transport);GO:0007015(actin filament organization);GO:0008064(regulation of actin polymerization or depolymerization);GO:0008360(regulation of cell shape);GO:0016477(cell migration);GO:0030335(positive regulation of cell migration);GO:0030833(regulation of actin filament polymerization);GO:0031339(negative regulation of vesicle fusion);GO:0032796(uropod organization);GO:0034097(response to cytokine);GO:0038180(nerve growth factor signaling pathway);GO:0042102(positive regulation of T cell proliferation);GO:0043029(T cell homeostasis);GO:0043524(negative regulation of neuron apoptotic process);GO:0048873(homeostasis of number of cells within a tissue);GO:0050870(positive regulation of T cell activation);GO:0051279(regulation of release of sequestered calcium ion into cytosol);GO:0061502(early endosome to recycling endosome transport);GO:0071353(cellular response to interleukin-4);GO:0001772(immunological synapse);GO:0005769(early endosome);GO:0005911(cell-cell junction);GO:0015629(actin cytoskeleton);GO:0030424(axon);GO:0031252(cell leading edge);GO:0045087(innate immune response);GO:0030027(lamellipodium);GO:0070062(extracellular exosome);GO:0001891(phagocytic cup);GO:0030670(phagocytic vesicle membrane);GO:0032956(regulation of actin cytoskeleton organization);GO:0005938(cell cortex);GO:0043234(protein complex);GO:0008022(protein C-terminus binding);GO:0043320(natural killer cell degranulation);GO:0006909(phagocytosis);GO:0030864(cortical actin cytoskeleton);GO:0030036(actin cytoskeleton organization);GO:0005884(actin filament);GO:0006928(movement of cell or subcellular component);GO:0050918(positive chemotaxis);GO:0003785(actin monomer binding);GO:0031589(cell-substrate adhesion);GO:0045335(phagocytic vesicle);GO:0043548(phosphatidylinositol 3-kinase binding);GO:0032036(myosin heavy chain binding);GO:0051126(negative regulation of actin nucleation)","04145(Phagosome);05152(Tuberculosis)","NA","NA","coronin 1A [Source:HGNC Symbol;Acc:HGNC:2252]",{"v":20.503746,"d":"20.50"},{"v":2.186684,"d":"2.19"},{"v":9.37663878274136,"d":"9.38"},{"v":3.2290708565884,"d":"3.23"},{"v":2.38889967954327E-5,"d":"0.00"},{"v":0.00132089199686035,"d":"0.00"},"up","yes"]
[70652,0,"chr16","-",21879338,21916024,"ENST00000523028",28,4131,"ENSG00000185710","SMG1P4","NA","NA","NA","NA","SMG1P4, nonsense mediated mRNA decay associated PI3K related kinase pseudogene 4 [Source:HGNC Symbol;Acc:HGNC:49861]",{"v":1.989751,"d":"1.99"},{"v":0.207284,"d":"0.21"},{"v":9.59915381795025,"d":"9.60"},{"v":3.26290723537001,"d":"3.26"},{"v":2.38972778894282e-05,"d":"0.00"},{"v":0.00132089199686035,"d":"0.00"},"up","yes"]
[42436,"j","chr12","+",54301164,54351820,"MSTRG.3410.2",9,2030,"MSTRG.3410","COPZ1","NA","NA","NA","NA","NA",{"v":1.248927,"d":"1.25"},{"v":8.783907,"d":"8.78"},{"v":0.142183540877653,"d":"0.14"},{"v":-2.81417362619248,"d":"-2.81"},{"v":2.40975580302013e-05,"d":"0.00"},{"v":1.32825202869533E-3,"d":"0.00"},"down","yes"]
[141763,"j","chr3","-",151326235,151329552,"MSTRG.11282.1",3,2006,"MSTRG.11282","P2RY13","NA","NA","NA","NA","NA",{"v":9.276397,"d":"9.28"},{"v":1.000287,"d":"1.00"},{"v":9.27373543792931,"d":"9.27"},{"v":3.21315056994819,"d":"3.21"},{"v":2.43529355942414E-5,"d":"0.00"},{"v":1.33859969316347E-3,"d":"0.00"},"up","yes"]
[23999,0,"chr10","-",121740424,121928036,"ENST00000369043",12,4900,"ENSG00000107669","ATE1","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016740(transferase activity);GO:0016746(transferase activity, transferring acyl groups);GO:0005515(protein binding);GO:0004057(arginyltransferase activity);GO:0016598(protein arginylation);GO:0010498(proteasomal protein catabolic process)","NA","NA","NA","arginyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:782]",{"v":0.14909,"d":"0.15"},{"v":1.109227,"d":"1.11"},{"v":0.134408917200898,"d":"0.13"},{"v":-2.89529923969663,"d":"-2.90"},{"v":2.4603413903853e-05,"d":"0.00"},{"v":0.00134862148013696,"d":"0.00"},"down","yes"]
[155833,0,"chr5","+",74640023,74721288,"ENST00000511181",14,2021,"MSTRG.12122","HEXB","GO:0005975(carbohydrate metabolic process);GO:0004553(hydrolase activity, hydrolyzing O-glycosyl compounds);GO:0016020(membrane);GO:0016787(hydrolase activity);GO:0008152(metabolic process);GO:0016798(hydrolase activity, acting on glycosyl bonds);GO:0005764(lysosome);GO:0005576(extracellular region);GO:0004563(beta-N-acetylhexosaminidase activity);GO:0006687(glycosphingolipid metabolic process);GO:0070062(extracellular exosome);GO:0043312(neutrophil degranulation);GO:0102148(-);GO:0042582(azurophil granule);GO:0043202(lysosomal lumen);GO:0035578(azurophil granule lumen);GO:0030207(chondroitin sulfate catabolic process);GO:0042803(protein homodimerization activity);GO:0046982(protein heterodimerization activity);GO:0042340(keratan sulfate catabolic process);GO:0030214(hyaluronan catabolic process);GO:0008375(acetylglucosaminyltransferase activity);GO:0001501(skeletal system development);GO:0006689(ganglioside catabolic process);GO:0006874(cellular calcium ion homeostasis);GO:0007040(lysosome organization);GO:0007338(single fertilization);GO:0007341(penetration of zona pellucida);GO:0007605(sensory perception of sound);GO:0007626(locomotory behavior);GO:0008049(male courtship behavior);GO:0008360(regulation of cell shape);GO:0008654(phospholipid biosynthetic process);GO:0009313(oligosaccharide catabolic process);GO:0019915(lipid storage);GO:0019953(sexual reproduction);GO:0030203(glycosaminoglycan metabolic process);GO:0031323(regulation of cellular metabolic process);GO:0042552(myelination);GO:0043615(astrocyte cell migration);GO:0044267(cellular protein metabolic process);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0048477(oogenesis);GO:0050885(neuromuscular process controlling balance);GO:0050905(neuromuscular process);GO:0001669(acrosomal vesicle);GO:0005615(extracellular space)","00520(Amino sugar and nucleotide sugar metabolism);00531(Glycosaminoglycan degradation);00603(Glycosphingolipid biosynthesis - globo and isoglobo series);00604(Glycosphingolipid biosynthesis - ganglio series);00511(Other glycan degradation);04142(Lysosome)","K12373","EC:3.2.1.52","hexosaminidase subunit beta [Source:HGNC Symbol;Acc:HGNC:4879]",{"v":0.58989,"d":"0.59"},{"v":4.276877,"d":"4.28"},{"v":0.137925406786307,"d":"0.14"},{"v":-2.85803985943921,"d":"-2.86"},{"v":2.48556772960829e-05,"d":"0.00"},{"v":1.35868547606323E-3,"d":"0.00"},"down","yes"]
[156367,0,"chr5","-",83052846,83077496,"ENST00000502346",4,4630,"MSTRG.12176","TMEM167A","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005794(Golgi apparatus);GO:0000139(Golgi membrane);GO:0012505(endomembrane system);GO:0009306(protein secretion);GO:0046907(intracellular transport)","NA","NA","NA","transmembrane protein 167A [Source:HGNC Symbol;Acc:HGNC:28330]",{"v":13.343365,"d":"13.34"},{"v":1.479425,"d":"1.48"},{"v":9.01929127870625,"d":"9.02"},{"v":3.17301407329587,"d":"3.17"},{"v":2.54838358043967e-05,"d":"0.00"},{"v":0.00138727313358644,"d":"0.00"},"up","yes"]
[26161,"j","chr11","-",6733731,6746470,"MSTRG.2203.3",2,541,"MSTRG.2203","GVINP1","NA","NA","NA","NA","NA",{"v":1.579829,"d":"1.58"},{"v":11.578406,"d":"11.58"},{"v":0.136446156750765,"d":"0.14"},{"v":-2.87359633578061,"d":"-2.87"},{"v":2.55188710645576E-5,"d":"0.00"},{"v":0.00138727313358644,"d":"0.00"},"down","yes"]
[53140,0,"chr14","-",23058567,23069525,"ENST00000473758",12,3540,"MSTRG.4182","ACIN1","GO:0003676(nucleic acid binding);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0005886(plasma membrane);GO:0003723(RNA binding);GO:0006397(mRNA processing);GO:0008380(RNA splicing);GO:0005634(nucleus);GO:0016607(nuclear speck);GO:0005515(protein binding);GO:0006915(apoptotic process);GO:0030218(erythrocyte differentiation);GO:0016887(ATPase activity);GO:0019899(enzyme binding);GO:0061574(ASAP complex);GO:0097194(execution phase of apoptosis);GO:0030263(apoptotic chromosome condensation);GO:0045657(positive regulation of monocyte differentiation);GO:0005730(nucleolus)","03040(Spliceosome);03013(RNA transport);03015(mRNA surveillance pathway)","NA","NA","apoptotic chromatin condensation inducer 1 [Source:HGNC Symbol;Acc:HGNC:17066]",{"v":5.001411,"d":"5.00"},{"v":0.542379,"d":"0.54"},{"v":9.2212475040516,"d":"9.22"},{"v":3.20496194004308,"d":"3.20"},{"v":2.59368176283688e-05,"d":"0.00"},{"v":1.40613081432921E-3,"d":"0.00"},"up","yes"]
[37920,"j","chr12","-",6570172,6607322,"MSTRG.3060.5",40,6284,"MSTRG.3060","CHD4","NA","NA","NA","NA","NA",{"v":5.378982,"d":"5.38"},{"v":0.591771,"d":"0.59"},{"v":9.0896343349032,"d":"9.09"},{"v":3.1842222576941,"d":"3.18"},{"v":2.60642645099058E-5,"d":"0.00"},{"v":1.40917941563393E-3,"d":"0.00"},"up","yes"]
[72961,0,"chr16","+",51645756,51647132,"ENST00000562726",1,1377,"MSTRG.5916","HNRNPA1P48","NA","NA","NA","NA","heterogeneous nuclear ribonucleoprotein A1 pseudogene 48 [Source:HGNC Symbol;Acc:HGNC:48778]",{"v":3.378005,"d":"3.38"},{"v":23.117348,"d":"23.12"},{"v":0.146124244009304,"d":"0.15"},{"v":-2.77473253406096,"d":"-2.77"},{"v":2.61986246321775E-5,"d":"0.00"},{"v":1.41258415319218E-3,"d":"0.00"},"down","yes"]
[36792,0,"chr11","+",126355660,126414604,"ENST00000227495",11,1790,"MSTRG.2976","ST3GAL4","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016740(transferase activity);GO:0008373(sialyltransferase activity);GO:0016757(transferase activity, transferring glycosyl groups);GO:0006486(protein glycosylation);GO:0097503(sialylation);GO:0005794(Golgi apparatus);GO:0005576(extracellular region);GO:0032580(Golgi cisterna membrane);GO:0070062(extracellular exosome);GO:0000139(Golgi membrane);GO:0050890(cognition);GO:0016266(O-glycan processing);GO:0018146(keratan sulfate biosynthetic process);GO:0009311(oligosaccharide metabolic process);GO:0003836(beta-galactoside (CMP) alpha-2,3-sialyltransferase activity);GO:0018279(protein N-linked glycosylation via asparagine);GO:0047288(monosialoganglioside sialyltransferase activity)","00601(Glycosphingolipid biosynthesis - lacto and neolacto series)","K03494","EC:2.4.99.4","ST3 beta-galactoside alpha-2,3-sialyltransferase 4 [Source:HGNC Symbol;Acc:HGNC:10864]",{"v":0.645326,"d":"0.65"},{"v":4.620797,"d":"4.62"},{"v":0.139656860061154,"d":"0.14"},{"v":-2.84004165314827,"d":"-2.84"},{"v":2.67960110277761E-5,"d":"0.00"},{"v":1.44086811472183E-3,"d":"0.00"},"down","yes"]
[201077,0,"chrX","-",153947553,153971807,"ENST00000310441",26,8869,"MSTRG.15492","HCFC1","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0006355(regulation of transcription, DNA-templated);GO:0016569(covalent chromatin modification);GO:0005515(protein binding);GO:0007049(cell cycle);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0003713(transcription coactivator activity);GO:0042802(identical protein binding);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0005654(nucleoplasm);GO:0045296(cadherin binding);GO:0043254(regulation of protein complex assembly);GO:0050821(protein stabilization);GO:0010628(positive regulation of gene expression);GO:0016579(protein deubiquitination);GO:0003682(chromatin binding);GO:0016032(viral process);GO:0006366(transcription from RNA polymerase II promoter);GO:0071339(MLL1 complex);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0007005(mitochondrion organization);GO:0048188(Set1C/COMPASS complex);GO:0045787(positive regulation of cell cycle);GO:0043995(histone acetyltransferase activity (H4-K5 specific));GO:0043996(histone acetyltransferase activity (H4-K8 specific));GO:0046972(histone acetyltransferase activity (H4-K16 specific));GO:0043981(histone H4-K5 acetylation);GO:0043982(histone H4-K8 acetylation);GO:0043984(histone H4-K16 acetylation);GO:0000123(histone acetyltransferase complex);GO:0005671(Ada2/Gcn5/Ada3 transcription activator complex);GO:0043025(neuronal cell body);GO:0033613(activating transcription factor binding);GO:0070461(SAGA-type complex);GO:0001205(transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding);GO:0019046(release from viral latency);GO:0071407(cellular response to organic cyclic compound);GO:0030424(axon);GO:0030425(dendrite)","05168(Herpes simplex infection)","K14966","NA","host cell factor C1 [Source:HGNC Symbol;Acc:HGNC:4839]",{"v":7.78693,"d":"7.79"},{"v":0.874379,"d":"0.87"},{"v":8.9056690519786,"d":"8.91"},{"v":3.15472400006505,"d":"3.15"},{"v":2.79074531986597E-5,"d":"0.00"},{"v":1.49656553901105E-3,"d":"0.00"},"up","yes"]
[64845,0,"chr15","+",75206049,75212169,"ENST00000567617",2,4249,"MSTRG.5289","C15orf39","GO:0005829(cytosol)","NA","NA","NA","chromosome 15 open reading frame 39 [Source:HGNC Symbol;Acc:HGNC:24497]",{"v":0.476978,"d":"0.48"},{"v":3.2922,"d":"3.29"},{"v":0.144881234432902,"d":"0.14"},{"v":-2.78705735122657,"d":"-2.79"},{"v":2.9301630293105E-5,"d":"0.00"},{"v":0.00156708286551341,"d":"0.00"},"down","yes"]
[12943,"j","chr1","+",161505430,161526907,"MSTRG.1158.3",9,6256,"MSTRG.1158","FCGR2A","NA","NA","NA","NA","NA",{"v":2.864573,"d":"2.86"},{"v":19.075876,"d":"19.08"},{"v":0.150167310796107,"d":"0.15"},{"v":-2.73535730124325,"d":"-2.74"},{"v":2.97415327792572E-5,"d":"0.00"},{"v":1.58632196936912E-3,"d":"0.00"},"down","yes"]
[8852,0,"chr1","+",109620654,109632051,"ENST00000256578",18,3899,"MSTRG.768","AMPD2","GO:0003876(AMP deaminase activity);GO:0032264(IMP salvage);GO:0046872(metal ion binding);GO:0016787(hydrolase activity);GO:0019239(deaminase activity);GO:0009168(purine ribonucleoside monophosphate biosynthetic process);GO:0005515(protein binding);GO:0009117(nucleotide metabolic process);GO:0005575(cellular_component);GO:0005829(cytosol);GO:0043101(purine-containing compound salvage);GO:0006188(IMP biosynthetic process);GO:0052652(cyclic purine nucleotide metabolic process);GO:0097009(energy homeostasis)","00230(Purine metabolism)","K01490","EC:3.5.4.6","adenosine monophosphate deaminase 2 [Source:HGNC Symbol;Acc:HGNC:469]",{"v":2.810425,"d":"2.81"},{"v":0.303701,"d":"0.30"},{"v":9.25392079709978,"d":"9.25"},{"v":3.21006475114869,"d":"3.21"},{"v":2.98793209507334E-5,"d":"0.00"},{"v":1.58938710476643E-3,"d":"0.00"},"up","yes"]
[151446,0,"chr4","-",150314723,151015277,"ENST00000507224",51,8826,"MSTRG.11855","LRBA","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005794(Golgi apparatus);GO:0005783(endoplasmic reticulum);GO:0005886(plasma membrane);GO:0005764(lysosome);GO:0003674(molecular_function);GO:0008150(biological_process)","NA","NA","NA","LPS responsive beige-like anchor protein [Source:HGNC Symbol;Acc:HGNC:1742]",{"v":5.181731,"d":"5.18"},{"v":0.584412,"d":"0.58"},{"v":8.86657187052969,"d":"8.87"},{"v":3.1483764155339,"d":"3.15"},{"v":3.01401948929479E-5,"d":"0.00"},{"v":1.5989656207551E-3,"d":"0.00"},"up","yes"]
[21652,0,"chr10","+",78033863,78037602,"ENST00000478655",4,727,"MSTRG.1826","RPS24","GO:0003723(RNA binding);GO:0005634(nucleus);GO:0016020(membrane);GO:0006412(translation);GO:0030529(intracellular ribonucleoprotein complex);GO:0005622(intracellular);GO:0003735(structural constituent of ribosome);GO:0005840(ribosome);GO:0022627(cytosolic small ribosomal subunit);GO:0006364(rRNA processing);GO:0042274(ribosomal small subunit biogenesis);GO:0000462(maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA));GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0006413(translational initiation);GO:0031369(translation initiation factor binding);GO:0000184(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay);GO:0019083(viral transcription);GO:0006614(SRP-dependent cotranslational protein targeting to membrane);GO:0034101(erythrocyte homeostasis);GO:0015935(small ribosomal subunit)","03010(Ribosome)","NA","NA","ribosomal protein S24 [Source:HGNC Symbol;Acc:HGNC:10411]",{"v":11.47671,"d":"11.48"},{"v":76.518623,"d":"76.52"},{"v":0.149985840701812,"d":"0.15"},{"v":-2.73710178425602,"d":"-2.74"},{"v":3.07844993696932e-05,"d":"0.00"},{"v":1.62877987574195E-3,"d":"0.00"},"down","yes"]
[104672,0,"chr19","-",51410021,51417803,"ENST00000353836",10,3109,"MSTRG.8375","SIGLEC10","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0030246(carbohydrate binding);GO:0007155(cell adhesion);GO:0005886(plasma membrane);GO:0005576(extracellular region)","NA","NA","NA","sialic acid binding Ig like lectin 10 [Source:HGNC Symbol;Acc:HGNC:15620]",{"v":6.076096,"d":"6.08"},{"v":0.677837,"d":"0.68"},{"v":8.96394855990452,"d":"8.96"},{"v":3.16413436988985,"d":"3.16"},{"v":3.10506487913064e-05,"d":"0.00"},{"v":0.00163848063541966,"d":"0.00"},"up","yes"]
[93657,0,"chr18","+",79069394,79378283,"ENST00000426216",30,4361,"ENSG00000166377","ATP9B","GO:0016021(integral component of membrane);GO:0005524(ATP binding);GO:0000287(magnesium ion binding);GO:0005802(trans-Golgi network);GO:0004012(phospholipid-translocating ATPase activity);GO:0015914(phospholipid transport);GO:0045332(phospholipid translocation);GO:0016020(membrane);GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0016787(hydrolase activity);GO:0005794(Golgi apparatus);GO:0048471(perinuclear region of cytoplasm);GO:0005886(plasma membrane);GO:0005768(endosome);GO:0006890(retrograde vesicle-mediated transport, Golgi to ER);GO:0006897(endocytosis)","NA","NA","NA","ATPase phospholipid transporting 9B (putative) [Source:HGNC Symbol;Acc:HGNC:13541]",{"v":2.034955,"d":"2.03"},{"v":0.21911,"d":"0.22"},{"v":9.28736707589795,"d":"9.29"},{"v":3.21526965743426,"d":"3.22"},{"v":3.17707801112117e-05,"d":"0.00"},{"v":1.67202180010813E-3,"d":"0.00"},"up","yes"]
[27932,0,"chr11","-",33858576,33865151,"ENST00000464025",2,1550,"MSTRG.2316","LMO2","GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0005515(protein binding);GO:0005654(nucleoplasm);GO:1902036(regulation of hematopoietic stem cell differentiation);GO:0005667(transcription factor complex);GO:0007275(multicellular organism development);GO:0043425(bHLH transcription factor binding);GO:0000981(RNA polymerase II transcription factor activity, sequence-specific DNA binding);GO:0001102(RNA polymerase II activating transcription factor binding);GO:0070888(E-box binding);GO:0000977(RNA polymerase II regulatory region sequence-specific DNA binding);GO:0001190(transcriptional activator activity, RNA polymerase II transcription factor binding);GO:0001228(transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding);GO:0097067(cellular response to thyroid hormone stimulus);GO:0042789(mRNA transcription from RNA polymerase II promoter);GO:0048037(cofactor binding)","05202(Transcriptional misregulation in cancers)","NA","NA","LIM domain only 2 [Source:HGNC Symbol;Acc:HGNC:6642]",{"v":15.767287,"d":"15.77"},{"v":1.777264,"d":"1.78"},{"v":8.87166284806309,"d":"8.87"},{"v":3.14920453945478,"d":"3.15"},{"v":3.22934649267495e-05,"d":"0.00"},{"v":1.69502144289262E-3,"d":"0.00"},"up","yes"]
[50327,0,"chr13","+",49451552,49495002,"ENST00000317257",13,5619,"ENSG00000136169","SETDB2","GO:0005634(nucleus);GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0008168(methyltransferase activity);GO:0016740(transferase activity);GO:0032259(methylation);GO:0016569(covalent chromatin modification);GO:0003677(DNA binding);GO:0051301(cell division);GO:0005694(chromosome);GO:0005515(protein binding);GO:0007049(cell cycle);GO:0007275(multicellular organism development);GO:0018024(histone-lysine N-methyltransferase activity);GO:0034968(histone lysine methylation);GO:0007059(chromosome segregation);GO:0045892(negative regulation of transcription, DNA-templated);GO:0000278(mitotic cell cycle);GO:0046974(histone methyltransferase activity (H3-K9 specific));GO:0001947(heart looping);GO:0070986(left/right axis specification);GO:0051567(histone H3-K9 methylation)","00310(Lysine degradation)","K18494","EC:2.1.1.43","SET domain bifurcated 2 [Source:HGNC Symbol;Acc:HGNC:20263]",{"v":0.324023,"d":"0.32"},{"v":2.213004,"d":"2.21"},{"v":0.146417719986046,"d":"0.15"},{"v":-2.77183793068497,"d":"-2.77"},{"v":3.26557493926379e-05,"d":"0.00"},{"v":0.00170950256344317,"d":"0.00"},"down","yes"]
[115259,0,"chr2","-",151247940,151261879,"ENST00000331426",4,4192,"ENSG00000184898","RBM43","GO:0003676(nucleic acid binding);GO:0003723(RNA binding)","NA","NA","NA","RNA binding motif protein 43 [Source:HGNC Symbol;Acc:HGNC:24790]",{"v":2.055471,"d":"2.06"},{"v":0.222218,"d":"0.22"},{"v":9.24979524610968,"d":"9.25"},{"v":3.20942143041905,"d":"3.21"},{"v":3.29287331985186e-05,"d":"0.00"},{"v":0.00171924478240709,"d":"0.00"},"up","yes"]
[115153,0,"chr2","+",148021011,148516971,"ENST00000407073",15,9512,"ENSG00000204406","MBD5","GO:0005634(nucleus);GO:0005694(chromosome);GO:0030496(midbody);GO:0007399(nervous system development);GO:0005654(nucleoplasm);GO:0070062(extracellular exosome);GO:0016579(protein deubiquitination);GO:0003682(chromatin binding);GO:0042593(glucose homeostasis);GO:0040014(regulation of multicellular organism growth);GO:0010369(chromocenter);GO:0044708(single-organism behavior);GO:0060399(positive regulation of growth hormone receptor signaling pathway);GO:0003677(DNA binding)","NA","NA","NA","methyl-CpG binding domain protein 5 [Source:HGNC Symbol;Acc:HGNC:20444]",{"v":0.763045,"d":"0.76"},{"v":0.081891,"d":"0.08"},{"v":9.31781270225055,"d":"9.32"},{"v":3.21999133106345,"d":"3.22"},{"v":3.34232711843854e-05,"d":"0.00"},{"v":0.00174047286893847,"d":"0.00"},"up","yes"]
[116344,0,"chr2","+",171687409,171748411,"ENST00000340296",16,2589,"MSTRG.9231","DYNC1I2","GO:0007018(microtubule-based movement);GO:0005868(cytoplasmic dynein complex);GO:0006810(transport);GO:0005737(cytoplasm);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0005874(microtubule);GO:0003774(motor activity);GO:0005813(centrosome);GO:0030286(dynein complex);GO:0005829(cytosol);GO:0016032(viral process);GO:0000086(G2/M transition of mitotic cell cycle);GO:0010389(regulation of G2/M transition of mitotic cell cycle);GO:0097711(ciliary basal body docking);GO:0007062(sister chromatid cohesion);GO:0019886(antigen processing and presentation of exogenous peptide antigen via MHC class II);GO:0031982(vesicle);GO:0006888(ER to Golgi vesicle-mediated transport);GO:0008574(ATP-dependent microtubule motor activity, plus-end-directed);GO:0045503(dynein light chain binding);GO:0045504(dynein heavy chain binding);GO:2000582(positive regulation of ATP-dependent microtubule motor activity, plus-end-directed);GO:0003777(microtubule motor activity);GO:0010970(transport along microtubule)","04145(Phagosome);04962(Vasopressin-regulated water reabsorption);05132(Salmonella infection)","K10415","NA","dynein cytoplasmic 1 intermediate chain 2 [Source:HGNC Symbol;Acc:HGNC:2964]",{"v":1.048437,"d":"1.05"},{"v":7.008435,"d":"7.01"},{"v":0.149596450562786,"d":"0.15"},{"v":-2.74085214971673,"d":"-2.74"},{"v":3.41599586873423e-05,"d":"0.00"},{"v":1.77416604332055E-3,"d":"0.00"},"down","yes"]
[79069,0,"chr17","+",7888791,7912760,"ENST00000358181",39,7286,"MSTRG.6408","CHD3","GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0005730(nucleolus);GO:0016787(hydrolase activity);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0016569(covalent chromatin modification);GO:0016575(histone deacetylation);GO:0004386(helicase activity);GO:0032508(DNA duplex unwinding);GO:0003677(DNA binding);GO:0008270(zinc ion binding);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0005815(microtubule organizing center);GO:0006325(chromatin organization);GO:0007098(centrosome cycle);GO:0005813(centrosome);GO:0007051(spindle organization);GO:0016581(NuRD complex);GO:0005654(nucleoplasm);GO:1901796(regulation of signal transduction by p53 class mediator);GO:0004407(histone deacetylase activity);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0004003(ATP-dependent DNA helicase activity);GO:0006333(chromatin assembly or disassembly)","NA","NA","NA","chromodomain helicase DNA binding protein 3 [Source:HGNC Symbol;Acc:HGNC:1918]",{"v":4.50744,"d":"4.51"},{"v":0.514863,"d":"0.51"},{"v":8.75463958373393,"d":"8.75"},{"v":3.13004778614452,"d":"3.13"},{"v":3.44710493857608e-05,"d":"0.00"},{"v":0.00178563645352208,"d":"0.00"},"up","yes"]
[199341,0,"chrX","+",110002635,110177784,"ENST00000372072",6,4975,"MSTRG.15402","TMEM164","GO:0016020(membrane);GO:0016021(integral component of membrane)","NA","NA","NA","transmembrane protein 164 [Source:HGNC Symbol;Acc:HGNC:26217]",{"v":0.811805,"d":"0.81"},{"v":5.370859,"d":"5.37"},{"v":0.151149937095723,"d":"0.15"},{"v":-2.72594771632999,"d":"-2.73"},{"v":3.49899289132651e-05,"d":"0.00"},{"v":0.00180778254134645,"d":"0.00"},"down","yes"]
[98241,0,"chr19","+",17305668,17306843,"ENST00000252602",2,968,"MSTRG.7957","MRPL34","GO:0005622(intracellular);GO:0003735(structural constituent of ribosome);GO:0006412(translation);GO:0005840(ribosome);GO:0030529(intracellular ribonucleoprotein complex);GO:0005739(mitochondrion);GO:0005743(mitochondrial inner membrane);GO:0070125(mitochondrial translational elongation);GO:0070126(mitochondrial translational termination);GO:0005761(mitochondrial ribosome);GO:0005762(mitochondrial large ribosomal subunit)","03010(Ribosome)","K02914","NA","mitochondrial ribosomal protein L34 [Source:HGNC Symbol;Acc:HGNC:14488]",{"v":2.251989,"d":"2.25"},{"v":15.115171,"d":"15.12"},{"v":0.148988655173005,"d":"0.15"},{"v":-2.74672561486283,"d":"-2.75"},{"v":3.5521345301003e-05,"d":"0.00"},{"v":0.00183045932504231,"d":"0.00"},"down","yes"]
[133789,0,"chr3","-",15667236,15859771,"ENST00000399451",28,6564,"MSTRG.10693","ANKRD28","GO:0005634(nucleus);GO:0005515(protein binding);GO:0005654(nucleoplasm);GO:0000139(Golgi membrane);GO:0005829(cytosol);GO:0048208(COPII vesicle coating)","NA","NA","NA","ankyrin repeat domain 28 [Source:HGNC Symbol;Acc:HGNC:29024]",{"v":1.485325,"d":"1.49"},{"v":0.164516,"d":"0.16"},{"v":9.02845315957111,"d":"9.03"},{"v":3.17447883264788,"d":"3.17"},{"v":3.61393922161349e-05,"d":"0.00"},{"v":0.00185747089135813,"d":"0.00"},"up","yes"]
[73885,0,"chr16","-",58543327,58629838,"ENST00000441024",31,4999,"MSTRG.5984","CNOT1","GO:0035195(gene silencing by miRNA);GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005829(cytosol);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0005515(protein binding);GO:0007275(multicellular organism development);GO:0005615(extracellular space);GO:0031047(gene silencing by RNA);GO:0010606(positive regulation of cytoplasmic mRNA processing body assembly);GO:0000932(P-body);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0006977(DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest);GO:0004535(poly(A)-specific ribonuclease activity);GO:0019904(protein domain specific binding);GO:0030331(estrogen receptor binding);GO:0032947(protein complex scaffold);GO:0042974(retinoic acid receptor binding);GO:0070016(armadillo repeat domain binding);GO:0000289(nuclear-transcribed mRNA poly(A) tail shortening);GO:0006417(regulation of translation);GO:0017148(negative regulation of translation);GO:0033147(negative regulation of intracellular estrogen receptor signaling pathway);GO:0048387(negative regulation of retinoic acid receptor signaling pathway);GO:0060213(positive regulation of nuclear-transcribed mRNA poly(A) tail shortening);GO:0061014(positive regulation of mRNA catabolic process);GO:0090503(RNA phosphodiester bond hydrolysis, exonucleolytic);GO:1900153(positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay);GO:2000036(regulation of stem cell population maintenance);GO:0030014(CCR4-NOT complex);GO:0030015(CCR4-NOT core complex)","03018(RNA degradation)","K12604","NA","CCR4-NOT transcription complex subunit 1 [Source:HGNC Symbol;Acc:HGNC:7877]",{"v":1.453847,"d":"1.45"},{"v":0.158315,"d":"0.16"},{"v":9.18325490319932,"d":"9.18"},{"v":3.19900559159256,"d":"3.20"},{"v":3.73503722838297e-05,"d":"0.00"},{"v":0.00191473877397,"d":"0.00"},"up","yes"]
[30565,0,"chr11","+",63839295,63909573,"ENST00000502399",18,2885,"MSTRG.2492","MARK2","GO:0003723(RNA binding);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0005654(nucleoplasm);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0005886(plasma membrane);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0007275(multicellular organism development);GO:0016055(Wnt signaling pathway);GO:0000287(magnesium ion binding);GO:0030154(cell differentiation);GO:0000226(microtubule cytoskeleton organization);GO:0030010(establishment of cell polarity);GO:0008289(lipid binding);GO:0045296(cadherin binding);GO:0016328(lateral plasma membrane);GO:0046777(protein autophosphorylation);GO:0005739(mitochondrion);GO:0035556(intracellular signal transduction);GO:0005884(actin filament);GO:0051493(regulation of cytoskeleton organization);GO:0050770(regulation of axonogenesis);GO:0010976(positive regulation of neuron projection development);GO:0001764(neuron migration);GO:0097427(microtubule bundle);GO:0000422(mitophagy);GO:0018107(peptidyl-threonine phosphorylation);GO:0050321(tau-protein kinase activity);GO:0045197(establishment or maintenance of epithelial cell apical/basal polarity);GO:0032147(activation of protein kinase activity);GO:0051646(mitochondrion localization);GO:0030295(protein kinase activator activity)","NA","NA","NA","microtubule affinity regulating kinase 2 [Source:HGNC Symbol;Acc:HGNC:3332]",{"v":4.678036,"d":"4.68"},{"v":0.526034,"d":"0.53"},{"v":8.89302972811643,"d":"8.89"},{"v":3.15267500837789,"d":"3.15"},{"v":3.77711139065357e-05,"d":"0.00"},{"v":0.00193130439788767,"d":"0.00"},"up","yes"]
[11398,"j","chr1","+",154328831,154349459,"MSTRG.1011.6",27,4128,"MSTRG.1011","ATP8B2","NA","NA","NA","NA","NA",{"v":0.989894,"d":"0.99"},{"v":6.471021,"d":"6.47"},{"v":0.152973387043559,"d":"0.15"},{"v":-2.70864740745861,"d":"-2.71"},{"v":3.79976570164946e-05,"d":"0.00"},{"v":0.00193788050784123,"d":"0.00"},"down","yes"]
[192636,0,"chr9","+",111661335,111670246,"ENST00000374293",3,1491,"MSTRG.14898","GNG10","GO:0016020(membrane);GO:0007186(G-protein coupled receptor signaling pathway);GO:0004871(signal transducer activity);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0007165(signal transduction);GO:0005834(heterotrimeric G-protein complex);GO:0070062(extracellular exosome);GO:0003924(GTPase activity);GO:0071377(cellular response to glucagon stimulus)","04014(Ras signaling pathway);04371(Apelin signaling pathway);04151(PI3K-Akt signaling pathway);04062(Chemokine signaling pathway);04926(Relaxin signaling pathway);04724(Glutamatergic synapse);04727(GABAergic synapse);04725(Cholinergic synapse);04728(Dopaminergic synapse);04726(Serotonergic synapse);04723(Retrograde endocannabinoid signaling);04713(Circadian entrainment);05200(Pathways in cancer);05032(Morphine addiction);05034(Alcoholism);05167(Kaposi's sarcoma-associated herpesvirus infection)","K04545","NA","G protein subunit gamma 10 [Source:HGNC Symbol;Acc:HGNC:4402]",{"v":40.748863,"d":"40.75"},{"v":4.747254,"d":"4.75"},{"v":8.58367026495738,"d":"8.58"},{"v":3.10159465714667,"d":"3.10"},{"v":3.81746616565759e-05,"d":"0.00"},{"v":0.0019419028402579,"d":"0.00"},"up","yes"]
[99972,0,"chr19","+",35154730,35166761,"ENST00000543307",8,1003,"MSTRG.8070","FXYD5","GO:0016020(membrane);GO:0005216(ion channel activity);GO:0006811(ion transport);GO:0034220(ion transmembrane transport);GO:0006810(transport);GO:0016021(integral component of membrane);GO:0003779(actin binding);GO:0005887(integral component of plasma membrane);GO:0017080(sodium channel regulator activity);GO:2000649(regulation of sodium ion transmembrane transporter activity);GO:0005515(protein binding);GO:0045296(cadherin binding);GO:0030033(microvillus assembly);GO:0046588(negative regulation of calcium-dependent cell-cell adhesion)","NA","NA","NA","FXYD domain containing ion transport regulator 5 [Source:HGNC Symbol;Acc:HGNC:4029]",{"v":6.992379,"d":"6.99"},{"v":0.756344,"d":"0.76"},{"v":9.24497186465418,"d":"9.24"},{"v":3.20866892906315,"d":"3.21"},{"v":3.92015622122224e-05,"d":"0.00"},{"v":0.00198902695655245,"d":"0.00"},"up","yes"]
[195707,"j","chrX","+",12906632,12913805,"MSTRG.15171.2",2,3733,"MSTRG.15171","TLR8","NA","NA","NA","NA","NA",{"v":5.74806,"d":"5.75"},{"v":0.661531,"d":"0.66"},{"v":8.68902591110621,"d":"8.69"},{"v":3.11919445183999,"d":"3.12"},{"v":3.96924407812252e-05,"d":"0.00"},{"v":0.00200878265518896,"d":"0.00"},"up","yes"]
[67231,0,"chr16","-",46407,53628,"ENST00000293860",3,1392,"ENSG00000161980","POLR3K","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0006351(transcription, DNA-templated);GO:0006379(mRNA cleavage);GO:0002376(immune system process);GO:0045087(innate immune response);GO:0005730(nucleolus);GO:0051607(defense response to virus);GO:0003899(DNA-directed 5'-3' RNA polymerase activity);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0001056(RNA polymerase III activity);GO:0032481(positive regulation of type I interferon production);GO:0005666(DNA-directed RNA polymerase III complex);GO:0006383(transcription from RNA polymerase III promoter);GO:0006386(termination of RNA polymerase III transcription)","00230(Purine metabolism);00240(Pyrimidine metabolism);03020(RNA polymerase);04623(Cytosolic DNA-sensing pathway);05169(Epstein-Barr virus infection)","K03019","NA","RNA polymerase III subunit K [Source:HGNC Symbol;Acc:HGNC:14121]",{"v":0.757346,"d":"0.76"},{"v":5.105246,"d":"5.11"},{"v":0.148346622278339,"d":"0.15"},{"v":-2.752956016588,"d":"-2.75"},{"v":4.21254087690649e-05,"d":"0.00"},{"v":0.002126473440618,"d":"0.00"},"down","yes"]
[122893,0,"chr20","-",32443059,32483471,"ENST00000359676",8,5991,"ENSG00000197183","NOL4L","GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0005515(protein binding)","NA","NA","NA","nucleolar protein 4 like [Source:HGNC Symbol;Acc:HGNC:16106]",{"v":2.625685,"d":"2.63"},{"v":0.303257,"d":"0.30"},{"v":8.65828323830942,"d":"8.66"},{"v":3.11408099618674,"d":"3.11"},{"v":4.23256782438771e-05,"d":"0.00"},{"v":2.13114636409629E-3,"d":"0.00"},"up","yes"]
[41130,"j","chr12","-",49002281,49060107,"MSTRG.3345.4",66,21796,"MSTRG.3345","KMT2D","NA","NA","NA","NA","NA",{"v":8.284481,"d":"8.28"},{"v":0.98755,"d":"0.99"},{"v":8.38892309250164,"d":"8.39"},{"v":3.0684856201018,"d":"3.07"},{"v":4.2873841517213e-05,"d":"0.00"},{"v":0.00215326795924521,"d":"0.00"},"up","yes"]
[155958,"o","chr5","-",76170738,76174209,"MSTRG.12132.1",2,1149,"MSTRG.12132","AC113404.3","NA","NA","NA","NA","NA",{"v":13.209632,"d":"13.21"},{"v":1.524998,"d":"1.52"},{"v":8.66206513057722,"d":"8.66"},{"v":3.11471102015514,"d":"3.11"},{"v":4.33946067176169E-5,"d":"0.00"},{"v":2.17390500690684E-3,"d":"0.00"},"up","yes"]
[53466,0,"chr14","+",24136227,24138967,"ENST00000561435",11,945,"MSTRG.4279","PSME1","GO:0005737(cytoplasm);GO:0005515(protein binding);GO:0000502(proteasome complex);GO:0008537(proteasome activator complex);GO:0038095(Fc-epsilon receptor signaling pathway);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0000165(MAPK cascade);GO:0000209(protein polyubiquitination);GO:0002223(stimulatory C-type lectin receptor signaling pathway);GO:0002479(antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent);GO:0006521(regulation of cellular amino acid metabolic process);GO:0010972(negative regulation of G2/M transition of mitotic cell cycle);GO:0016579(protein deubiquitination);GO:0031145(anaphase-promoting complex-dependent catabolic process);GO:0031146(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process);GO:0033209(tumor necrosis factor-mediated signaling pathway);GO:0038061(NIK/NF-kappaB signaling);GO:0043161(proteasome-mediated ubiquitin-dependent protein catabolic process);GO:0043488(regulation of mRNA stability);GO:0043687(post-translational protein modification);GO:0050852(T cell receptor signaling pathway);GO:0051437(positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition);GO:0055085(transmembrane transport);GO:0060071(Wnt signaling pathway, planar cell polarity pathway);GO:0061418(regulation of transcription from RNA polymerase II promoter in response to hypoxia);GO:0090090(negative regulation of canonical Wnt signaling pathway);GO:0090263(positive regulation of canonical Wnt signaling pathway);GO:1902036(regulation of hematopoietic stem cell differentiation);GO:0051436(negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle);GO:2000045(regulation of G1/S transition of mitotic cell cycle);GO:0061133(endopeptidase activator activity);GO:0010950(positive regulation of endopeptidase activity);GO:0061136(regulation of proteasomal protein catabolic process);GO:0019884(antigen processing and presentation of exogenous antigen)","03050(Proteasome);04612(Antigen processing and presentation)","K06696","NA","proteasome activator subunit 1 [Source:HGNC Symbol;Acc:HGNC:9568]",{"v":24.024895,"d":"24.02"},{"v":2.814337,"d":"2.81"},{"v":8.53660915519357,"d":"8.54"},{"v":3.09366312764085,"d":"3.09"},{"v":4.52342944026984e-05,"d":"0.00"},{"v":0.0022603439839409,"d":"0.00"},"up","yes"]
[143494,0,"chr3","+",184315166,184335358,"ENST00000342981",32,5667,"MSTRG.11394","EIF4G1","GO:0003723(RNA binding);GO:0016020(membrane);GO:0003743(translation initiation factor activity);GO:0006412(translation);GO:0006413(translational initiation);GO:0006446(regulation of translational initiation);GO:0005515(protein binding);GO:0008190(eukaryotic initiation factor 4E binding);GO:0005829(cytosol);GO:0045296(cadherin binding);GO:0043488(regulation of mRNA stability);GO:0000289(nuclear-transcribed mRNA poly(A) tail shortening);GO:0006417(regulation of translation);GO:0016032(viral process);GO:0010507(negative regulation of autophagy);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0008135(translation factor activity, RNA binding);GO:0007005(mitochondrion organization);GO:0005524(ATP binding);GO:0000184(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay);GO:0016281(eukaryotic translation initiation factor 4F complex);GO:1901215(negative regulation of neuron death);GO:0033138(positive regulation of peptidyl-serine phosphorylation);GO:0008284(positive regulation of cell proliferation);GO:1905606(regulation of presynapse assembly);GO:0010801(negative regulation of peptidyl-threonine phosphorylation);GO:0030307(positive regulation of cell growth);GO:0034645(cellular macromolecule biosynthetic process);GO:0022627(cytosolic small ribosomal subunit);GO:0003729(mRNA binding);GO:0031369(translation initiation factor binding);GO:0032947(protein complex scaffold);GO:0002191(cap-dependent translational initiation);GO:0032270(positive regulation of cellular protein metabolic process);GO:0032502(developmental process);GO:0060964(regulation of gene silencing by miRNA);GO:0080135(regulation of cellular response to stress);GO:1900087(positive regulation of G1/S transition of mitotic cell cycle);GO:1905537(positive regulation of eukaryotic translation initiation factor 4F complex assembly);GO:1905612(positive regulation of mRNA cap binding);GO:1905618(positive regulation of miRNA mediated inhibition of translation);GO:1905696(regulation of polysome binding);GO:2000507(positive regulation of energy homeostasis);GO:0005844(polysome);GO:0001662(behavioral fear response);GO:0045666(positive regulation of neuron differentiation)","03013(RNA transport);05416(Viral myocarditis)","K03260","NA","eukaryotic translation initiation factor 4 gamma 1 [Source:HGNC Symbol;Acc:HGNC:3296]",{"v":1.195769,"d":"1.20"},{"v":0.133161,"d":"0.13"},{"v":8.97987398712836,"d":"8.98"},{"v":3.16669520004208,"d":"3.17"},{"v":4.55883329121086e-05,"d":"0.00"},{"v":2.27149499767128E-3,"d":"0.00"},"up","yes"]
[22606,0,"chr10","-",97356701,97373593,"ENST00000479481",17,3271,"MSTRG.1890","RRP12","GO:0003723(RNA binding);GO:0005634(nucleus);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005730(nucleolus);GO:0031965(nuclear membrane)","NA","NA","NA","ribosomal RNA processing 12 homolog [Source:HGNC Symbol;Acc:HGNC:29100]",{"v":0.386216,"d":"0.39"},{"v":2.547681,"d":"2.55"},{"v":0.151595117285092,"d":"0.15"},{"v":-2.72170480827827,"d":"-2.72"},{"v":4.583854261655e-05,"d":"0.00"},{"v":2.27149499767128E-3,"d":"0.00"},"down","yes"]
[30124,0,"chr11","-",61964566,61967633,"ENST00000534180",4,983,"MSTRG.2449","FTH1","GO:0005623(cell);GO:0008199(ferric iron binding);GO:0006826(iron ion transport);GO:0006879(cellular iron ion homeostasis);GO:0046872(metal ion binding);GO:0005634(nucleus);GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0005515(protein binding);GO:0006955(immune response);GO:0005576(extracellular region);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0008285(negative regulation of cell proliferation);GO:0043312(neutrophil degranulation);GO:1904813(ficolin-1-rich granule lumen);GO:1904724(tertiary granule lumen);GO:0004322(ferroxidase activity);GO:0048147(negative regulation of fibroblast proliferation);GO:0005506(iron ion binding);GO:0008043(intracellular ferritin complex);GO:0044754(autolysosome);GO:0006880(intracellular sequestering of iron ion);GO:0016020(membrane);GO:0016021(integral component of membrane)","04216(Ferroptosis);04217(Necroptosis);04978(Mineral absorption)","NA","NA","ferritin heavy chain 1 [Source:HGNC Symbol;Acc:HGNC:3976]",{"v":21.782665,"d":"21.78"},{"v":137.24588,"d":"137.25"},{"v":0.158712705984325,"d":"0.16"},{"v":-2.65551046497007,"d":"-2.66"},{"v":4.58820153141355e-05,"d":"0.00"},{"v":2.27149499767128E-3,"d":"0.00"},"down","yes"]
[96791,0,"chr19","+",11435745,11450867,"ENST00000587327",17,2189,"MSTRG.7840","PRKCSH","GO:0046872(metal ion binding);GO:0005783(endoplasmic reticulum);GO:0005509(calcium ion binding);GO:0044267(cellular protein metabolic process);GO:0005622(intracellular);GO:0043687(post-translational protein modification);GO:0044325(ion channel binding);GO:0006457(protein folding);GO:0006491(N-glycan processing);GO:0005788(endoplasmic reticulum lumen);GO:0035556(intracellular signal transduction);GO:0051219(phosphoprotein binding);GO:0005080(protein kinase C binding);GO:0003723(RNA binding);GO:0001701(in utero embryonic development);GO:0001889(liver development);GO:0006807(nitrogen compound metabolic process);GO:0010977(negative regulation of neuron projection development);GO:0051291(protein heterooligomerization);GO:0072001(renal system development)","04141(Protein processing in endoplasmic reticulum)","K08288","NA","protein kinase C substrate 80K-H [Source:HGNC Symbol;Acc:HGNC:9411]",{"v":0.403964,"d":"0.40"},{"v":2.776378,"d":"2.78"},{"v":0.145500360541684,"d":"0.15"},{"v":-2.78090536683246,"d":"-2.78"},{"v":4.5916616083915e-05,"d":"0.00"},{"v":2.27149499767128E-3,"d":"0.00"},"down","yes"]
[48043,0,"chr12","-",123295905,123364828,"ENST00000602398",32,4313,"MSTRG.3833","SBNO1","GO:0006355(regulation of transcription, DNA-templated);GO:0003674(molecular_function);GO:0008150(biological_process);GO:0005575(cellular_component)","NA","NA","NA","strawberry notch homolog 1 [Source:HGNC Symbol;Acc:HGNC:22973]",{"v":7.446255,"d":"7.45"},{"v":0.882771,"d":"0.88"},{"v":8.43509245319568,"d":"8.44"},{"v":3.0764038813209,"d":"3.08"},{"v":4.63462072429071E-5,"d":"0.00"},{"v":0.00228702929905897,"d":"0.00"},"up","yes"]
[31886,0,"chr11","+",67288547,67302481,"ENST00000447274",15,2881,"MSTRG.2599","ANKRD13D","GO:0016020(membrane);GO:0005886(plasma membrane);GO:0005737(cytoplasm);GO:0005768(endosome);GO:0005770(late endosome)","NA","NA","NA","ankyrin repeat domain 13D [Source:HGNC Symbol;Acc:HGNC:27880]",{"v":1.230575,"d":"1.23"},{"v":7.860023,"d":"7.86"},{"v":0.156561246703731,"d":"0.16"},{"v":-2.67520094552354,"d":"-2.68"},{"v":4.65563576579489e-05,"d":"0.00"},{"v":0.0022916845903868,"d":"0.00"},"down","yes"]
[11829,"j","chr1","+",155688009,155739010,"MSTRG.1064.5",14,2236,"MSTRG.1064","DAP3","NA","NA","NA","NA","NA",{"v":9.618155,"d":"9.62"},{"v":1.131516,"d":"1.13"},{"v":8.50023773415489,"d":"8.50"},{"v":3.08750319102564,"d":"3.09"},{"v":4.67096511649194e-05,"d":"0.00"},{"v":0.00229267431802294,"d":"0.00"},"up","yes"]
[112838,0,"chr2","-",99400475,99489973,"ENST00000393445",23,4686,"MSTRG.9003","REV1","GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0016740(transferase activity);GO:0003677(DNA binding);GO:0003684(damaged DNA binding);GO:0006281(DNA repair);GO:0005515(protein binding);GO:0006974(cellular response to DNA damage stimulus);GO:0016779(nucleotidyltransferase activity);GO:0005654(nucleoplasm);GO:0071897(DNA biosynthetic process);GO:0009411(response to UV);GO:0019985(translesion synthesis);GO:0042276(error-prone translesion synthesis);GO:0006260(DNA replication);GO:0017125(deoxycytidyl transferase activity)","03460(Fanconi anemia pathway)","K03515","EC:2.7.7.-","REV1, DNA directed polymerase [Source:HGNC Symbol;Acc:HGNC:14060]",{"v":0.208913,"d":"0.21"},{"v":1.405,"d":"1.41"},{"v":0.148692526690391,"d":"0.15"},{"v":-2.74959595575293,"d":"-2.75"},{"v":4.6808188017044e-05,"d":"0.00"},{"v":0.00229267431802294,"d":"0.00"},"down","yes"]
[112918,0,"chr2","+",101001715,101007267,"ENST00000264258",5,1865,"MSTRG.9009","RPL31","GO:0003723(RNA binding);GO:0016020(membrane);GO:0006412(translation);GO:0030529(intracellular ribonucleoprotein complex);GO:0005622(intracellular);GO:0003735(structural constituent of ribosome);GO:0005840(ribosome);GO:0005925(focal adhesion);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0005515(protein binding);GO:0002181(cytoplasmic translation);GO:0006413(translational initiation);GO:0006364(rRNA processing);GO:0000184(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay);GO:0019083(viral transcription);GO:0006614(SRP-dependent cotranslational protein targeting to membrane);GO:0022625(cytosolic large ribosomal subunit)","03010(Ribosome)","K02910","NA","ribosomal protein L31 [Source:HGNC Symbol;Acc:HGNC:10334]",{"v":0.778879,"d":"0.78"},{"v":5.143911,"d":"5.14"},{"v":0.151417666440963,"d":"0.15"},{"v":-2.72339455535062,"d":"-2.72"},{"v":4.73644175945729e-05,"d":"0.00"},{"v":2.31419035891706E-3,"d":"0.00"},"down","yes"]
[24633,0,"chr11","-",202926,207428,"ENST00000382762",4,2819,"MSTRG.2074","BET1L","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0015031(protein transport);GO:0005829(cytosol);GO:0005794(Golgi apparatus);GO:0000139(Golgi membrane);GO:0061025(membrane fusion);GO:0006888(ER to Golgi vesicle-mediated transport);GO:0005484(SNAP receptor activity);GO:0042147(retrograde transport, endosome to Golgi);GO:0031201(SNARE complex);GO:0005768(endosome);GO:2000156(regulation of retrograde vesicle-mediated transport, Golgi to ER)","04130(SNARE interactions in vesicular transport)","K08504","NA","Bet1 golgi vesicular membrane trafficking protein like [Source:HGNC Symbol;Acc:HGNC:19348]",{"v":1.358312,"d":"1.36"},{"v":8.641361,"d":"8.64"},{"v":0.157187276402409,"d":"0.16"},{"v":-2.66944365218941,"d":"-2.67"},{"v":4.80748783410734e-05,"d":"0.00"},{"v":0.00234311746949054,"d":"0.00"},"down","yes"]
[178352,0,"chr7","-",124822386,124929981,"ENST00000357628",19,4080,"ENSG00000128513","POT1","GO:0000723(telomere maintenance);GO:0043047(single-stranded telomeric DNA binding);GO:0005634(nucleus);GO:0003677(DNA binding);GO:0005694(chromosome);GO:0005515(protein binding);GO:0000784(nuclear chromosome, telomeric region);GO:0000781(chromosome, telomeric region);GO:0005654(nucleoplasm);GO:0032212(positive regulation of telomere maintenance via telomerase);GO:0051973(positive regulation of telomerase activity);GO:0070200(establishment of protein localization to telomere);GO:0000783(nuclear telomere cap complex);GO:0042162(telomeric DNA binding);GO:0032508(DNA duplex unwinding);GO:0032210(regulation of telomere maintenance via telomerase);GO:0051974(negative regulation of telomerase activity);GO:0032211(negative regulation of telomere maintenance via telomerase);GO:0098505(G-rich strand telomeric DNA binding);GO:0051096(positive regulation of helicase activity);GO:0061821(telomeric D-loop binding);GO:1905773(8-hydroxy-2'-deoxyguanosine DNA binding);GO:0061820(telomeric D-loop disassembly);GO:0007004(telomere maintenance via telomerase);GO:0016233(telomere capping);GO:0070187(shelterin complex);GO:0017151(DEAD/H-box RNA helicase binding);GO:0032202(telomere assembly);GO:0010521(telomerase inhibitor activity);GO:1990955(G-rich single-stranded DNA binding);GO:0060383(positive regulation of DNA strand elongation);GO:1905774(regulation of DNA helicase activity);GO:1905776(positive regulation of DNA helicase activity)","NA","NA","NA","protection of telomeres 1 [Source:HGNC Symbol;Acc:HGNC:17284]",{"v":0.694158,"d":"0.69"},{"v":4.444452,"d":"4.44"},{"v":0.156185284485016,"d":"0.16"},{"v":-2.67866956330624,"d":"-2.68"},{"v":4.83695442909813e-05,"d":"0.00"},{"v":0.00234878181765692,"d":"0.00"},"down","yes"]
[31336,0,"chr11","-",65653596,65663094,"ENST00000406246",11,2700,"MSTRG.2557","RELA","GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0006355(regulation of transcription, DNA-templated);GO:0006366(transcription from RNA polymerase II promoter);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0031490(chromatin DNA binding);GO:0042803(protein homodimerization activity);GO:0005515(protein binding);GO:0051092(positive regulation of NF-kappaB transcription factor activity);GO:0045893(positive regulation of transcription, DNA-templated);GO:0006954(inflammatory response);GO:0038095(Fc-epsilon receptor signaling pathway);GO:0042802(identical protein binding);GO:0071159(NF-kappaB complex);GO:0051607(defense response to virus);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:0001078(transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0005654(nucleoplasm);GO:0019901(protein kinase binding);GO:0002223(stimulatory C-type lectin receptor signaling pathway);GO:0050852(T cell receptor signaling pathway);GO:0003682(chromatin binding);GO:0071347(cellular response to interleukin-1);GO:0071356(cellular response to tumor necrosis factor);GO:0016032(viral process);GO:0031625(ubiquitin protein ligase binding);GO:0043123(positive regulation of I-kappaB kinase/NF-kappaB signaling);GO:0008284(positive regulation of cell proliferation);GO:0047485(protein N-terminus binding);GO:0043066(negative regulation of apoptotic process);GO:0008134(transcription factor binding);GO:0044212(transcription regulatory region DNA binding);GO:0045892(negative regulation of transcription, DNA-templated);GO:0000790(nuclear chromatin);GO:0046982(protein heterodimerization activity);GO:0010033(response to organic substance);GO:0001077(transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0000977(RNA polymerase II regulatory region sequence-specific DNA binding);GO:1902895(positive regulation of pri-miRNA transcription from RNA polymerase II promoter);GO:0032481(positive regulation of type I interferon production);GO:0019221(cytokine-mediated signaling pathway);GO:0042826(histone deacetylase binding);GO:0051059(NF-kappaB binding);GO:0070555(response to interleukin-1);GO:0043620(regulation of DNA-templated transcription in response to stress);GO:1901223(negative regulation of NIK/NF-kappaB signaling);GO:0005667(transcription factor complex);GO:0071223(cellular response to lipoteichoic acid);GO:0000983(transcription factor activity, RNA polymerase II core promoter sequence-specific);GO:0006968(cellular defense response);GO:0050727(regulation of inflammatory response);GO:1901224(positive regulation of NIK/NF-kappaB signaling);GO:0070301(cellular response to hydrogen peroxide);GO:0042301(phosphate ion binding);GO:0003705(transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding);GO:2000630(positive regulation of miRNA metabolic process);GO:2001237(negative regulation of extrinsic apoptotic signaling pathway);GO:0010224(response to UV-B);GO:0031293(membrane protein intracellular domain proteolysis);GO:0000980(RNA polymerase II distal enhancer sequence-specific DNA binding);GO:0001205(transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding);GO:0071375(cellular response to peptide hormone stimulus);GO:0042805(actinin binding);GO:0071316(cellular response to nicotine);GO:0071354(cellular response to interleukin-6);GO:0070491(repressing transcription factor binding);GO:0050862(positive regulation of T cell receptor signaling pathway);GO:0033209(tumor necrosis factor-mediated signaling pathway);GO:0033613(activating transcription factor binding);GO:1901222(regulation of NIK/NF-kappaB signaling);GO:0033256(I-kappaB/NF-kappaB complex);GO:0001046(core promoter sequence-specific DNA binding);GO:0019899(enzyme binding);GO:0032403(protein complex binding);GO:0043565(sequence-specific DNA binding);GO:0071532(ankyrin repeat binding);GO:0001889(liver development);GO:0001942(hair follicle development);GO:0006117(acetaldehyde metabolic process);GO:0006952(defense response);GO:0007568(aging);GO:0009612(response to mechanical stimulus);GO:0009617(response to bacterium);GO:0009887(animal organ morphogenesis);GO:0010035(response to inorganic substance);GO:0014040(positive regulation of Schwann cell differentiation);GO:0014070(response to organic cyclic compound);GO:0032332(positive regulation of chondrocyte differentiation);GO:0032495(response to muramyl dipeptide);GO:0032496(response to lipopolysaccharide);GO:0032570(response to progesterone);GO:0032868(response to insulin);GO:0033234(negative regulation of protein sumoylation);GO:0033590(response to cobalamin);GO:0034097(response to cytokine);GO:0035729(cellular response to hepatocyte growth factor stimulus);GO:0035994(response to muscle stretch);GO:0042177(negative regulation of protein catabolic process);GO:0042493(response to drug);GO:0042542(response to hydrogen peroxide);GO:0043200(response to amino acid);GO:0043278(response to morphine);GO:0045084(positive regulation of interleukin-12 biosynthetic process);GO:0046627(negative regulation of insulin receptor signaling pathway);GO:0051591(response to cAMP);GO:0070431(nucleotide-binding oligomerization domain containing 2 signaling pathway);GO:0071222(cellular response to lipopolysaccharide);GO:0071224(cellular response to peptidoglycan);GO:1901522(positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus);GO:0035525(NF-kappaB p50/p65 complex);GO:0043234(protein complex)","04014(Ras signaling pathway);04010(MAPK signaling pathway);04064(NF-kappa B signaling pathway);04668(TNF signaling pathway);04066(HIF-1 signaling pathway);04071(Sphingolipid signaling pathway);04024(cAMP signaling pathway);04151(PI3K-Akt signaling pathway);04137(Mitophagy - animal);04210(Apoptosis);04218(Cellular senescence);04620(Toll-like receptor signaling pathway);04621(NOD-like receptor signaling pathway);04622(RIG-I-like receptor signaling pathway);04623(Cytosolic DNA-sensing pathway);04660(T cell receptor signaling pathway);04658(Th1 and Th2 cell differentiation);04659(Th17 cell differentiation);04657(IL-17 signaling pathway);04662(B cell receptor signaling pathway);04062(Chemokine signaling pathway);04920(Adipocytokine signaling pathway);04917(Prolactin signaling pathway);04926(Relaxin signaling pathway);04722(Neurotrophin signaling pathway);04380(Osteoclast differentiation);04211(Longevity regulating pathway - mammal);05200(Pathways in cancer);05202(Transcriptional misregulation in cancers);05203(Viral carcinogenesis);05212(Pancreatic cancer);05221(Acute myeloid leukemia);05220(Chronic myeloid leukemia);05215(Prostate cancer);05222(Small cell lung cancer);05321(Inflammatiory bowel disease (IBD));05030(Cocaine addiction);05418(Fluid shear stress and atherosclerosis);04932(Non-alcoholic fatty liver disease (NAFLD));04931(Insulin resistance);04933(AGE-RAGE signaling pathway in diabetic complications);05120(Epithelial cell signaling in Helicobacter pylori infection);05132(Salmonella infection);05131(Shigellosis);05133(Pertussis);05134(Legionellosis);05152(Tuberculosis);05166(HTLV-I infection);05162(Measles);05164(Influenza A);05161(Hepatitis B);05160(Hepatitis C);05168(Herpes simplex infection);05167(Kaposi's sarcoma-associated herpesvirus infection);05169(Epstein-Barr virus infection);05165(Human papillomavirus infection);05146(Amoebiasis);05145(Toxoplasmosis);05140(Leishmaniasis);05142(Chagas disease (American trypanosomiasis));01523(Antifolate resistance)","K04735","NA","RELA proto-oncogene, NF-kB subunit [Source:HGNC Symbol;Acc:HGNC:9955]",{"v":14.946331,"d":"14.95"},{"v":1.788533,"d":"1.79"},{"v":8.35675439032995,"d":"8.36"},{"v":3.06294273487293,"d":"3.06"},{"v":4.84890871275789e-05,"d":"0.00"},{"v":0.00234878181765692,"d":"0.00"},"up","yes"]
[1929,0,"chr1","+",15847864,15940460,"ENST00000375759",15,12232,"MSTRG.183","SPEN","GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0007219(Notch signaling pathway);GO:0070062(extracellular exosome);GO:0000398(mRNA splicing, via spliceosome);GO:0016032(viral process);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0045892(negative regulation of transcription, DNA-templated);GO:0001085(RNA polymerase II transcription factor binding);GO:0001191(transcriptional repressor activity, RNA polymerase II transcription factor binding);GO:0017053(transcriptional repressor complex);GO:0050769(positive regulation of neurogenesis)","NA","NA","NA","spen family transcriptional repressor [Source:HGNC Symbol;Acc:HGNC:17575]",{"v":10.247795,"d":"10.25"},{"v":1.240065,"d":"1.24"},{"v":8.26391761722168,"d":"8.26"},{"v":3.04682587208558,"d":"3.05"},{"v":4.85471883677824e-05,"d":"0.00"},{"v":0.00234878181765692,"d":"0.00"},"up","yes"]
[2023,0,"chr1","+",16440736,16460077,"ENST00000443980",7,1929,"MSTRG.190","NECAP2","GO:0006810(transport);GO:0016020(membrane);GO:0015031(protein transport);GO:0006897(endocytosis);GO:0005886(plasma membrane);GO:0031410(cytoplasmic vesicle);GO:0005905(clathrin-coated pit);GO:0030665(clathrin-coated vesicle membrane);GO:0005622(intracellular);GO:0030125(clathrin vesicle coat)","NA","NA","NA","NECAP endocytosis associated 2 [Source:HGNC Symbol;Acc:HGNC:25528]",{"v":1.177019,"d":"1.18"},{"v":7.595551,"d":"7.60"},{"v":0.154961634778043,"d":"0.15"},{"v":-2.69001701594626,"d":"-2.69"},{"v":4.87068260376462E-5,"d":"0.00"},{"v":2.35075774056815E-3,"d":"0.00"},"down","yes"]
[100369,0,"chr19","-",35904403,35908275,"ENST00000544690",4,522,"MSTRG.8084","TYROBP","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005515(protein binding);GO:0050776(regulation of immune response);GO:0005886(plasma membrane);GO:0042802(identical protein binding);GO:0045087(innate immune response);GO:0005887(integral component of plasma membrane);GO:0005102(receptor binding);GO:0043312(neutrophil degranulation);GO:0007165(signal transduction);GO:0009986(cell surface);GO:0030667(secretory granule membrane);GO:0035556(intracellular signal transduction);GO:0005057(signal transducer activity, downstream of receptor);GO:0006968(cellular defense response);GO:0002281(macrophage activation involved in immune response);GO:0002283(neutrophil activation involved in immune response);GO:0007229(integrin-mediated signaling pathway);GO:2001204(regulation of osteoclast development)","04650(Natural killer cell mediated cytotoxicity);04380(Osteoclast differentiation)","K07992","NA","TYRO protein tyrosine kinase binding protein [Source:HGNC Symbol;Acc:HGNC:12449]",{"v":4.332754,"d":"4.33"},{"v":27.83535,"d":"27.84"},{"v":0.155656530275351,"d":"0.16"},{"v":-2.68356199126859,"d":"-2.68"},{"v":4.99217929279768e-05,"d":"0.00"},{"v":0.00240353391352507,"d":"0.00"},"down","yes"]
[122639,0,"chr20","-",25674215,25696841,"ENST00000252979",5,3205,"ENSG00000130684","ZNF337","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0005622(intracellular);GO:0005515(protein binding)","NA","NA","NA","zinc finger protein 337 [Source:HGNC Symbol;Acc:HGNC:15809]",{"v":0.433308,"d":"0.43"},{"v":2.83533,"d":"2.84"},{"v":0.152824538942557,"d":"0.15"},{"v":-2.71005188025501,"d":"-2.71"},{"v":5.03757162394534e-05,"d":"0.00"},{"v":0.00241950163336482,"d":"0.00"},"down","yes"]
[43271,0,"chr12","-",57096200,57111346,"ENST00000538913",20,2879,"MSTRG.3477","STAT6","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0006355(regulation of transcription, DNA-templated);GO:0006366(transcription from RNA polymerase II promoter);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0031965(nuclear membrane);GO:0007165(signal transduction);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0004871(signal transducer activity);GO:0005515(protein binding);GO:0042802(identical protein binding);GO:0001228(transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0019903(protein phosphatase binding);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0000977(RNA polymerase II regulatory region sequence-specific DNA binding);GO:0032481(positive regulation of type I interferon production);GO:0000979(RNA polymerase II core promoter sequence-specific DNA binding);GO:0043565(sequence-specific DNA binding);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0002296(T-helper 1 cell lineage commitment);GO:0002829(negative regulation of type 2 immune response);GO:0019221(cytokine-mediated signaling pathway);GO:0033598(mammary gland epithelial cell proliferation);GO:0034097(response to cytokine);GO:0035771(interleukin-4-mediated signaling pathway);GO:0042127(regulation of cell proliferation);GO:0048295(positive regulation of isotype switching to IgE isotypes);GO:0060443(mammary gland morphogenesis);GO:0070301(cellular response to hydrogen peroxide);GO:1902170(cellular response to reactive nitrogen species);GO:0000790(nuclear chromatin);GO:0045121(membrane raft)","04630(Jak-STAT signaling pathway);04217(Necroptosis);04658(Th1 and Th2 cell differentiation);04659(Th17 cell differentiation);05200(Pathways in cancer);05321(Inflammatiory bowel disease (IBD));05161(Hepatitis B)","K11225","NA","signal transducer and activator of transcription 6 [Source:HGNC Symbol;Acc:HGNC:11368]",{"v":4.965721,"d":"4.97"},{"v":0.583785,"d":"0.58"},{"v":8.50607843641066,"d":"8.51"},{"v":3.08849415843169,"d":"3.09"},{"v":5.05015374622695e-05,"d":"0.00"},{"v":2.41967172712685E-3,"d":"0.00"},"up","yes"]
[197148,0,"chrX","-",49074433,49080097,"ENST00000465806",9,2610,"MSTRG.15298","WDR45","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0032266(phosphatidylinositol-3-phosphate binding);GO:0080025(phosphatidylinositol-3,5-bisphosphate binding);GO:0000422(mitophagy);GO:0005829(cytosol);GO:0006497(protein lipidation);GO:0034497(protein localization to pre-autophagosomal structure);GO:0044804(nucleophagy);GO:0019898(extrinsic component of membrane);GO:0034045(pre-autophagosomal structure membrane);GO:0006914(autophagy)","NA","NA","NA","WD repeat domain 45 [Source:HGNC Symbol;Acc:HGNC:28912]",{"v":0.332278,"d":"0.33"},{"v":2.229462,"d":"2.23"},{"v":0.149039544069376,"d":"0.15"},{"v":-2.74623292887317,"d":"-2.75"},{"v":5.09488161242838e-05,"d":"0.00"},{"v":0.00243520573301287,"d":"0.00"},"down","yes"]
[79048,0,"chr17","+",7839962,7853680,"ENST00000448097",23,5422,"MSTRG.6404","KDM6B","GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0005634(nucleus);GO:0048333(mesodermal cell differentiation);GO:0046872(metal ion binding);GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0016569(covalent chromatin modification);GO:0005515(protein binding);GO:0051213(dioxygenase activity);GO:0006954(inflammatory response);GO:0071558(histone demethylase activity (H3-K27 specific));GO:0071557(histone H3-K27 demethylation);GO:0005654(nucleoplasm);GO:0032452(histone demethylase activity);GO:0003682(chromatin binding);GO:0008013(beta-catenin binding);GO:0043565(sequence-specific DNA binding);GO:0002437(inflammatory response to antigenic stimulus);GO:0010468(regulation of gene expression);GO:0014823(response to activity);GO:0016577(histone demethylation);GO:0021766(hippocampus development);GO:0045165(cell fate commitment);GO:0045446(endothelial cell differentiation);GO:0055007(cardiac muscle cell differentiation);GO:0060992(response to fungicide);GO:0070301(cellular response to hydrogen peroxide)","NA","NA","NA","lysine demethylase 6B [Source:HGNC Symbol;Acc:HGNC:29012]",{"v":27.569714,"d":"27.57"},{"v":3.363057,"d":"3.36"},{"v":8.19781347744032,"d":"8.20"},{"v":3.03523916510892,"d":"3.04"},{"v":5.13031499958707e-05,"d":"0.00"},{"v":0.00244623308944166,"d":"0.00"},"up","yes"]
[42205,"j","chr12","+",53452311,53475553,"MSTRG.3414.26",14,1797,"MSTRG.3414","PCBP2","NA","NA","NA","NA","NA",{"v":10.949471,"d":"10.95"},{"v":1.30239,"d":"1.30"},{"v":8.40721366103855,"d":"8.41"},{"v":3.0716277382378,"d":"3.07"},{"v":5.14284744526674e-05,"d":"0.00"},{"v":0.00244631406843602,"d":"0.00"},"up","yes"]
[144687,"j","chr3","+",196739619,196832488,"MSTRG.11460.1",16,6337,"MSTRG.11460","PAK2","NA","NA","NA","NA","NA",{"v":8.028349,"d":"8.03"},{"v":0.972174,"d":"0.97"},{"v":8.25814000374419,"d":"8.26"},{"v":3.04581687734132,"d":"3.05"},{"v":5.16180662167783e-05,"d":"0.00"},{"v":0.00244944435083359,"d":"0.00"},"up","yes"]
[87995,0,"chr17","+",75456641,75500090,"ENST00000581085",31,5432,"ENSG00000177728","TMEM94","GO:0016020(membrane);GO:0016021(integral component of membrane)","NA","NA","NA","transmembrane protein 94 [Source:HGNC Symbol;Acc:HGNC:28983]",{"v":1.920484,"d":"1.92"},{"v":0.224568,"d":"0.22"},{"v":8.55190410031705,"d":"8.55"},{"v":3.09624567499798,"d":"3.10"},{"v":5.47347721575976e-05,"d":"0.00"},{"v":0.00259112840060895,"d":"0.00"},"up","yes"]
[33319,0,"chr11","-",76349956,76380942,"ENST00000260045",5,3300,"MSTRG.2726","THAP12","GO:0003676(nucleic acid binding);GO:0046872(metal ion binding);GO:0046983(protein dimerization activity);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0005737(cytoplasm);GO:0005634(nucleus);GO:0000981(RNA polymerase II transcription factor activity, sequence-specific DNA binding);GO:0005654(nucleoplasm);GO:0006950(response to stress);GO:0007165(signal transduction);GO:0008285(negative regulation of cell proliferation)","NA","NA","NA","THAP domain containing 12 [Source:HGNC Symbol;Acc:HGNC:9440]",{"v":2.310138,"d":"2.31"},{"v":14.313457,"d":"14.31"},{"v":0.16139623013504,"d":"0.16"},{"v":-2.63132121409695,"d":"-2.63"},{"v":5.4913161342772e-05,"d":"0.00"},{"v":0.0025917268182582,"d":"0.00"},"down","yes"]
[180082,0,"chr7","-",150625378,150632648,"ENST00000618759",3,3910,"MSTRG.14126","GIMAP6","GO:0005737(cytoplasm);GO:0005525(GTP binding);GO:0000166(nucleotide binding);GO:0005829(cytosol)","NA","NA","NA","GTPase, IMAP family member 6 [Source:HGNC Symbol;Acc:HGNC:21918]",{"v":0.269288,"d":"0.27"},{"v":1.754544,"d":"1.75"},{"v":0.153480334491469,"d":"0.15"},{"v":-2.7038742806546,"d":"-2.70"},{"v":5.50093624251286e-05,"d":"0.00"},{"v":0.0025917268182582,"d":"0.00"},"down","yes"]
[130511,0,"chr22","-",31618491,31628221,"ENST00000382151",8,2669,"MSTRG.10401","PISD","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005743(mitochondrial inner membrane);GO:0016829(lyase activity);GO:0006629(lipid metabolic process);GO:0005739(mitochondrion);GO:0008654(phospholipid biosynthetic process);GO:0004609(phosphatidylserine decarboxylase activity);GO:0016831(carboxy-lyase activity);GO:0006646(phosphatidylethanolamine biosynthetic process);GO:0016540(protein autoprocessing);GO:0031305(integral component of mitochondrial inner membrane);GO:0005634(nucleus)","00564(Glycerophospholipid metabolism)","NA","NA","phosphatidylserine decarboxylase [Source:HGNC Symbol;Acc:HGNC:8999]",{"v":3.245803,"d":"3.25"},{"v":0.378064,"d":"0.38"},{"v":8.58532682297177,"d":"8.59"},{"v":3.1018730552415,"d":"3.10"},{"v":5.53294760799058e-05,"d":"0.00"},{"v":0.00260061679968926,"d":"0.00"},"up","yes"]
[122192,0,"chr20","-",17941597,17968720,"ENST00000377759",13,2270,"MSTRG.9600","SNX5","GO:0006810(transport);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0006886(intracellular protein transport);GO:0015031(protein transport);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0042995(cell projection);GO:0005515(protein binding);GO:0030659(cytoplasmic vesicle membrane);GO:0031410(cytoplasmic vesicle);GO:0035091(phosphatidylinositol binding);GO:0006907(pinocytosis);GO:0008289(lipid binding);GO:0005768(endosome);GO:0045296(cadherin binding);GO:0006897(endocytosis);GO:0031234(extrinsic component of cytoplasmic side of plasma membrane);GO:0001891(phagocytic cup);GO:0005769(early endosome);GO:0042147(retrograde transport, endosome to Golgi);GO:0031901(early endosome membrane);GO:0001726(ruffle);GO:0046982(protein heterodimerization activity);GO:0016241(regulation of macroautophagy);GO:0030904(retromer complex);GO:0016050(vesicle organization);GO:0030905(retromer, tubulation complex);GO:0097422(tubular endosome);GO:0031313(extrinsic component of endosome membrane);GO:0034452(dynactin binding);GO:0070685(macropinocytic cup);GO:0005622(intracellular)","04144(Endocytosis)","K17920","NA","sorting nexin 5 [Source:HGNC Symbol;Acc:HGNC:14969]",{"v":8.907774,"d":"8.91"},{"v":1.072001,"d":"1.07"},{"v":8.30948292025847,"d":"8.31"},{"v":3.05475870424124,"d":"3.05"},{"v":5.6525512141895e-05,"d":"0.00"},{"v":0.00265053752195218,"d":"0.00"},"up","yes"]
[186053,"j","chr8","-",100703035,100722092,"MSTRG.14502.5",16,2637,"MSTRG.14502","PABPC1","NA","NA","NA","NA","NA",{"v":76.242889,"d":"76.24"},{"v":9.428748,"d":"9.43"},{"v":8.08621558238697,"d":"8.09"},{"v":3.01546466706429,"d":"3.02"},{"v":5.69003706602478e-05,"d":"0.00"},{"v":0.00266035244368619,"d":"0.00"},"up","yes"]
[62444,0,"chr15","-",50277263,50355153,"ENST00000220429",9,2726,"ENSG00000104064","GABPB1","GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0005515(protein binding);GO:0000932(P-body);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0007005(mitochondrion organization);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0046982(protein heterodimerization activity);GO:0044212(transcription regulatory region DNA binding)","NA","NA","NA","GA binding protein transcription factor beta subunit 1 [Source:HGNC Symbol;Acc:HGNC:4074]",{"v":0.317246,"d":"0.32"},{"v":2.104653,"d":"2.10"},{"v":0.15073553692699,"d":"0.15"},{"v":-2.72990851269376,"d":"-2.73"},{"v":5.70085187762101e-05,"d":"0.00"},{"v":0.00266035244368619,"d":"0.00"},"down","yes"]
[106942,0,"chr2","+",3575205,3580919,"ENST00000304921",7,786,"MSTRG.8494","RPS7","GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0006412(translation);GO:0030529(intracellular ribonucleoprotein complex);GO:0005622(intracellular);GO:0003735(structural constituent of ribosome);GO:0005840(ribosome);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0022627(cytosolic small ribosomal subunit);GO:0005730(nucleolus);GO:0005925(focal adhesion);GO:0006364(rRNA processing);GO:0005813(centrosome);GO:0005815(microtubule organizing center);GO:0042274(ribosomal small subunit biogenesis);GO:0032040(small-subunit processome);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0019901(protein kinase binding);GO:0043234(protein complex);GO:0031012(extracellular matrix);GO:0002181(cytoplasmic translation);GO:0006413(translational initiation);GO:0030686(90S preribosome);GO:0000184(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay);GO:0019083(viral transcription);GO:0003730(mRNA 3'-UTR binding);GO:0048027(mRNA 5'-UTR binding);GO:0006614(SRP-dependent cotranslational protein targeting to membrane);GO:0010628(positive regulation of gene expression);GO:0050821(protein stabilization);GO:1990948(ubiquitin ligase inhibitor activity);GO:1904667(negative regulation of ubiquitin protein ligase activity);GO:2000059(negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process);GO:0008266(poly(U) RNA binding);GO:1902255(positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator)","03010(Ribosome)","K02993","NA","ribosomal protein S7 [Source:HGNC Symbol;Acc:HGNC:10440]",{"v":64.950188,"d":"64.95"},{"v":397.098633,"d":"397.10"},{"v":0.163561852402549,"d":"0.16"},{"v":-2.61209178772704,"d":"-2.61"},{"v":5.72397943501547e-05,"d":"0.00"},{"v":0.00266035244368619,"d":"0.00"},"down","yes"]
[119342,0,"chr2","-",219219380,219229626,"ENST00000409033",16,3701,"MSTRG.9447","ATG9A","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0015031(protein transport);GO:0043231(intracellular membrane-bounded organelle);GO:0005794(Golgi apparatus);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005515(protein binding);GO:0006914(autophagy);GO:0031410(cytoplasmic vesicle);GO:0005768(endosome);GO:0031902(late endosome membrane);GO:0000422(mitophagy);GO:0034497(protein localization to pre-autophagosomal structure);GO:0005802(trans-Golgi network);GO:0005776(autophagosome);GO:0000045(autophagosome assembly);GO:0044805(late nucleophagy);GO:0055037(recycling endosome);GO:0005770(late endosome);GO:0000407(pre-autophagosomal structure);GO:0030659(cytoplasmic vesicle membrane);GO:0031667(response to nutrient levels)","04140(Autophagy - animal);04136(Autophagy - other eukaryotes);04137(Mitophagy - animal)","K17907","NA","autophagy related 9A [Source:HGNC Symbol;Acc:HGNC:22408]",{"v":2.092169,"d":"2.09"},{"v":0.240142,"d":"0.24"},{"v":8.71221610547093,"d":"8.71"},{"v":3.12303974037535,"d":"3.12"},{"v":5.72725965742024e-05,"d":"0.00"},{"v":0.00266035244368619,"d":"0.00"},"up","yes"]
[12975,0,"chr1","-",161541765,161550623,"ENST00000436743",6,2167,"MSTRG.1160","FCGR3A","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005886(plasma membrane);GO:0005576(extracellular region);GO:0038096(Fc-gamma receptor signaling pathway involved in phagocytosis);GO:0050776(regulation of immune response);GO:0070062(extracellular exosome);GO:0006955(immune response);GO:0019864(IgG binding);GO:0009897(external side of plasma membrane)","04145(Phagosome);04650(Natural killer cell mediated cytotoxicity);04666(Fc gamma R-mediated phagocytosis);04380(Osteoclast differentiation);05322(Systemic lupus erythematosus);05150(Staphylococcus aureus infection);05152(Tuberculosis);05140(Leishmaniasis)","K06463","NA","Fc fragment of IgG receptor IIIa [Source:HGNC Symbol;Acc:HGNC:3619]",{"v":9.993711,"d":"9.99"},{"v":61.120861,"d":"61.12"},{"v":0.163507366167502,"d":"0.16"},{"v":-2.61257246287079,"d":"-2.61"},{"v":5.77008266903432e-05,"d":"0.00"},{"v":0.00267396711603867,"d":"0.00"},"down","yes"]
[28081,0,"chr11","+",35662805,35818007,"ENST00000299413",5,12964,"MSTRG.2324","TRIM44","GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0005622(intracellular);GO:0005515(protein binding);GO:0010468(regulation of gene expression)","NA","NA","NA","tripartite motif containing 44 [Source:HGNC Symbol;Acc:HGNC:19016]",{"v":0.498731,"d":"0.50"},{"v":3.073349,"d":"3.07"},{"v":0.162276070826971,"d":"0.16"},{"v":-2.62347781862732,"d":"-2.62"},{"v":5.86672262603402e-05,"d":"0.00"},{"v":0.00271239970383087,"d":"0.00"},"down","yes"]
[164448,0,"chr6","-",31580555,31582427,"ENST00000446745",3,853,"MSTRG.12863","LTB","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0006955(immune response);GO:0005125(cytokine activity);GO:0005615(extracellular space);GO:0005164(tumor necrosis factor receptor binding);GO:0005886(plasma membrane);GO:0005575(cellular_component);GO:0033209(tumor necrosis factor-mediated signaling pathway);GO:0007165(signal transduction);GO:0007267(cell-cell signaling);GO:0045084(positive regulation of interleukin-12 biosynthetic process);GO:0005102(receptor binding);GO:0010467(gene expression);GO:0043588(skin development);GO:0048535(lymph node development)","04064(NF-kappa B signaling pathway);04060(Cytokine-cytokine receptor interaction);05323(Rheumatoid arthritis)","K03157","NA","lymphotoxin beta [Source:HGNC Symbol;Acc:HGNC:6711]",{"v":7.109955,"d":"7.11"},{"v":43.734722,"d":"43.73"},{"v":0.162570028454737,"d":"0.16"},{"v":-2.62086678941376,"d":"-2.62"},{"v":5.88312078860808e-05,"d":"0.00"},{"v":0.0027136408896265,"d":"0.00"},"down","yes"]
[17050,0,"chr1","-",232983435,233295713,"ENST00000258229",34,7518,"ENSG00000135749","PCNX2","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0003674(molecular_function);GO:0008150(biological_process);GO:0005575(cellular_component)","NA","NA","NA","pecanex homolog 2 [Source:HGNC Symbol;Acc:HGNC:8736]",{"v":1.489282,"d":"1.49"},{"v":0.177303,"d":"0.18"},{"v":8.39964354805051,"d":"8.40"},{"v":3.07032810618054,"d":"3.07"},{"v":5.93605474292243e-05,"d":"0.00"},{"v":0.00273168956402207,"d":"0.00"},"up","yes"]
[130513,0,"chr22","-",31618491,31662215,"ENST00000460723",7,2534,"MSTRG.10401","PISD","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005743(mitochondrial inner membrane);GO:0016829(lyase activity);GO:0006629(lipid metabolic process);GO:0005739(mitochondrion);GO:0008654(phospholipid biosynthetic process);GO:0004609(phosphatidylserine decarboxylase activity);GO:0016831(carboxy-lyase activity);GO:0006646(phosphatidylethanolamine biosynthetic process);GO:0016540(protein autoprocessing);GO:0031305(integral component of mitochondrial inner membrane);GO:0005634(nucleus)","00564(Glycerophospholipid metabolism)","NA","NA","phosphatidylserine decarboxylase [Source:HGNC Symbol;Acc:HGNC:8999]",{"v":2.579238,"d":"2.58"},{"v":0.296312,"d":"0.30"},{"v":8.7044669132536,"d":"8.70"},{"v":3.12175594576204,"d":"3.12"},{"v":5.98439122228236e-05,"d":"0.00"},{"v":2.74591527085522E-3,"d":"0.00"},"up","yes"]
[132507,0,"chr22","-",50274979,50307627,"ENST00000449103",37,6383,"MSTRG.10594","PLXNB2","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0007165(signal transduction);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0007275(multicellular organism development);GO:0017154(semaphorin receptor activity);GO:0071526(semaphorin-plexin signaling pathway);GO:0005887(integral component of plasma membrane);GO:0070062(extracellular exosome);GO:0008360(regulation of cell shape);GO:0043087(regulation of GTPase activity);GO:0009986(cell surface);GO:0007405(neuroblast proliferation);GO:0007420(brain development);GO:0001843(neural tube closure);GO:0001932(regulation of protein phosphorylation);GO:0007156(homophilic cell adhesion via plasma membrane adhesion molecules);GO:0007162(negative regulation of cell adhesion);GO:0010976(positive regulation of neuron projection development);GO:0050772(positive regulation of axonogenesis);GO:2001222(regulation of neuron migration)","04360(Axon guidance)","K06821","NA","plexin B2 [Source:HGNC Symbol;Acc:HGNC:9104]",{"v":4.413375,"d":"4.41"},{"v":0.539402,"d":"0.54"},{"v":8.18197744910104,"d":"8.18"},{"v":3.0324495609225,"d":"3.03"},{"v":5.99472102794348e-05,"d":"0.00"},{"v":2.74591527085522E-3,"d":"0.00"},"up","yes"]
[66305,"j","chr15","-",89784889,89815397,"MSTRG.5406.1",21,3715,"MSTRG.5406","ANPEP","NA","NA","NA","NA","NA",{"v":21.421848,"d":"21.42"},{"v":2.658243,"d":"2.66"},{"v":8.05864926569919,"d":"8.06"},{"v":3.01053804458677,"d":"3.01"},{"v":6.0881513989586e-05,"d":"0.00"},{"v":2.77590600267305E-3,"d":"0.00"},"up","yes"]
[15651,0,"chr1","+",209756032,209779655,"ENST00000400959",14,1854,"MSTRG.1365","TRAF3IP3","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005515(protein binding)","NA","NA","NA","TRAF3 interacting protein 3 [Source:HGNC Symbol;Acc:HGNC:30766]",{"v":0.455076,"d":"0.46"},{"v":2.974978,"d":"2.97"},{"v":0.152967853879928,"d":"0.15"},{"v":-2.70869959177811,"d":"-2.71"},{"v":6.0882514916116e-05,"d":"0.00"},{"v":2.77590600267305E-3,"d":"0.00"},"down","yes"]
[67291,0,"chr16","+",172894,173675,"ENST00000482565",2,640,"MSTRG.5480","HBA2","GO:0010942(positive regulation of cell death);GO:0006810(transport);GO:0016020(membrane);GO:0046872(metal ion binding);GO:0005506(iron ion binding);GO:0005515(protein binding);GO:0022627(cytosolic small ribosomal subunit);GO:0005615(extracellular space);GO:0020037(heme binding);GO:0098869(cellular oxidant detoxification);GO:0006898(receptor-mediated endocytosis);GO:0005576(extracellular region);GO:0005344(oxygen transporter activity);GO:0019825(oxygen binding);GO:0015671(oxygen transport);GO:0005833(hemoglobin complex);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0072562(blood microparticle);GO:0015701(bicarbonate transport);GO:0042542(response to hydrogen peroxide);GO:0031838(haptoglobin-hemoglobin complex);GO:0071682(endocytic vesicle lumen);GO:0004601(peroxidase activity);GO:0042744(hydrogen peroxide catabolic process);GO:0031720(haptoglobin binding);GO:0051291(protein heterooligomerization)","05144(Malaria);05143(African trypanosomiasis)","NA","NA","hemoglobin subunit alpha 2 [Source:HGNC Symbol;Acc:HGNC:4824]",{"v":374.135895,"d":"374.14"},{"v":2266.390625,"d":"2266.39"},{"v":0.165080057635696,"d":"0.17"},{"v":-2.59876224773025,"d":"-2.60"},{"v":6.11456818977863e-05,"d":"0.00"},{"v":0.00277805750066624,"d":"0.00"},"down","yes"]
[7008,0,"chr1","-",66999332,67054099,"ENST00000235345",12,6162,"MSTRG.628","SLC35D1","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0008643(carbohydrate transport);GO:0006065(UDP-glucuronate biosynthetic process);GO:0015165(pyrimidine nucleotide-sugar transmembrane transporter activity);GO:0090481(pyrimidine nucleotide-sugar transmembrane transport);GO:0005461(UDP-glucuronic acid transmembrane transporter activity);GO:0015787(UDP-glucuronic acid transport)","NA","NA","NA","solute carrier family 35 member D1 [Source:HGNC Symbol;Acc:HGNC:20800]",{"v":2.496361,"d":"2.50"},{"v":0.303109,"d":"0.30"},{"v":8.23585244911896,"d":"8.24"},{"v":3.0419179833418,"d":"3.04"},{"v":6.12104846518334e-05,"d":"0.00"},{"v":0.00277805750066624,"d":"0.00"},"up","yes"]
[59407,0,"chr14","+",105419822,105470729,"ENST00000331320",21,2876,"ENSG00000182979","MTA1","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0043231(intracellular membrane-bounded organelle);GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0016575(histone deacetylation);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0043565(sequence-specific DNA binding);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0048511(rhythmic process);GO:0005874(microtubule);GO:0003682(chromatin binding);GO:0003713(transcription coactivator activity);GO:1903507(negative regulation of nucleic acid-templated transcription);GO:0001047(core promoter binding);GO:0003714(transcription corepressor activity);GO:0007165(signal transduction);GO:0043161(proteasome-mediated ubiquitin-dependent protein catabolic process);GO:0032922(circadian regulation of gene expression);GO:0004407(histone deacetylase activity);GO:0001046(core promoter sequence-specific DNA binding);GO:0005635(nuclear envelope);GO:0001103(RNA polymerase II repressing transcription factor binding);GO:0016925(protein sumoylation);GO:0043153(entrainment of circadian clock by photoperiod);GO:0006302(double-strand break repair);GO:0040029(regulation of gene expression, epigenetic);GO:0045475(locomotor rhythm);GO:0010212(response to ionizing radiation);GO:1902499(positive regulation of protein autoubiquitination)","NA","NA","NA","metastasis associated 1 [Source:HGNC Symbol;Acc:HGNC:7410]",{"v":4.84377,"d":"4.84"},{"v":0.581995,"d":"0.58"},{"v":8.32270036684164,"d":"8.32"},{"v":3.05705169829064,"d":"3.06"},{"v":6.14980706418909e-05,"d":"0.00"},{"v":0.0027847227044891,"d":"0.00"},"up","yes"]
[37919,"j","chr12","-",6570130,6607476,"MSTRG.3060.4",40,6501,"MSTRG.3060","CHD4","NA","NA","NA","NA","NA",{"v":4.79741,"d":"4.80"},{"v":0.591235,"d":"0.59"},{"v":8.11421854254231,"d":"8.11"},{"v":3.02045215958092,"d":"3.02"},{"v":6.25067884199735e-05,"d":"0.00"},{"v":0.00282393682478182,"d":"0.00"},"up","yes"]
[51103,0,"chr13","-",79318868,79406221,"ENST00000622611",22,5230,"MSTRG.4030","RBM26","GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0046872(metal ion binding);GO:0005515(protein binding);GO:0006397(mRNA processing);GO:0010923(negative regulation of phosphatase activity)","NA","NA","NA","RNA binding motif protein 26 [Source:HGNC Symbol;Acc:HGNC:20327]",{"v":1.478131,"d":"1.48"},{"v":0.172236,"d":"0.17"},{"v":8.5820095682668,"d":"8.58"},{"v":3.10131550957888,"d":"3.10"},{"v":6.30267446289459e-05,"d":"0.00"},{"v":0.00284094128181681,"d":"0.00"},"up","yes"]
[145723,0,"chr4","-",6687448,6690519,"ENST00000499502",3,1821,"MSTRG.11520","LINC002481","NA","NA","NA","NA","long intergenic non-protein coding RNA 2481 [Source:HGNC Symbol;Acc:HGNC:27958]",{"v":0.542813,"d":"0.54"},{"v":3.45952,"d":"3.46"},{"v":0.156904136990103,"d":"0.16"},{"v":-2.67204470347095,"d":"-2.67"},{"v":6.5196495106013e-05,"d":"0.00"},{"v":0.00293206419354042,"d":"0.00"},"down","yes"]
[9844,0,"chr1","+",120813906,120841481,"ENST00000609741",22,3671,"ENSG00000273136","NBPF26","GO:0005509(calcium ion binding);GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process)","NA","NA","NA","NBPF member 26 [Source:HGNC Symbol;Acc:HGNC:49571]",{"v":2.722405,"d":"2.72"},{"v":0.325031,"d":"0.33"},{"v":8.37583184373183,"d":"8.38"},{"v":3.06623247848536,"d":"3.07"},{"v":6.53723804693031E-5,"d":"0.00"},{"v":0.00293330762976546,"d":"0.00"},"up","yes"]
[121710,0,"chr20","+",3796291,3806115,"ENST00000439880",16,3096,"MSTRG.9573","CDC25B","GO:0005737(cytoplasm);GO:0016787(hydrolase activity);GO:0005622(intracellular);GO:0051301(cell division);GO:0004725(protein tyrosine phosphatase activity);GO:0006470(protein dephosphorylation);GO:0035335(peptidyl-tyrosine dephosphorylation);GO:0004721(phosphoprotein phosphatase activity);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0007049(cell cycle);GO:1902751(positive regulation of cell cycle G2/M phase transition);GO:0000922(spindle pole);GO:0005813(centrosome);GO:0005815(microtubule organizing center);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0019901(protein kinase binding);GO:0000086(G2/M transition of mitotic cell cycle);GO:0006468(protein phosphorylation);GO:0000278(mitotic cell cycle);GO:0032467(positive regulation of cytokinesis);GO:0008284(positive regulation of cell proliferation);GO:0045931(positive regulation of mitotic cell cycle);GO:0001556(oocyte maturation);GO:0007144(female meiosis I);GO:0045860(positive regulation of protein kinase activity);GO:0005634(nucleus)","04010(MAPK signaling pathway);04110(Cell cycle);04914(Progesterone-mediated oocyte maturation);05206(MicroRNAs in cancer)","K05866","EC:3.1.3.48","cell division cycle 25B [Source:HGNC Symbol;Acc:HGNC:1726]",{"v":4.490095,"d":"4.49"},{"v":0.546597,"d":"0.55"},{"v":8.21463527973992,"d":"8.21"},{"v":3.03819652261403,"d":"3.04"},{"v":6.58424947646489e-05,"d":"0.00"},{"v":0.00294771784254044,"d":"0.00"},"up","yes"]
[2363,0,"chr1","-",20499448,20508161,"ENST00000264198",4,2438,"MSTRG.211","MUL1","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0046872(metal ion binding);GO:0016740(transferase activity);GO:0016567(protein ubiquitination);GO:0004842(ubiquitin-protein transferase activity);GO:0005739(mitochondrion);GO:0005515(protein binding);GO:0004871(signal transducer activity);GO:0006915(apoptotic process);GO:0005741(mitochondrial outer membrane);GO:0006996(organelle organization);GO:0031647(regulation of protein stability);GO:0051881(regulation of mitochondrial membrane potential);GO:1903861(positive regulation of dendrite extension);GO:1904925(positive regulation of mitophagy in response to mitochondrial depolarization);GO:0005777(peroxisome);GO:0050821(protein stabilization);GO:0042802(identical protein binding);GO:0045824(negative regulation of innate immune response);GO:0031625(ubiquitin protein ligase binding);GO:0016925(protein sumoylation);GO:0043123(positive regulation of I-kappaB kinase/NF-kappaB signaling);GO:0030308(negative regulation of cell growth);GO:0000266(mitochondrial fission);GO:0006919(activation of cysteine-type endopeptidase activity involved in apoptotic process);GO:0051898(negative regulation of protein kinase B signaling);GO:0010821(regulation of mitochondrion organization);GO:0031648(protein destabilization);GO:0043025(neuronal cell body);GO:0033235(positive regulation of protein sumoylation);GO:0071360(cellular response to exogenous dsRNA);GO:0051646(mitochondrion localization);GO:0030424(axon);GO:0060339(negative regulation of type I interferon-mediated signaling pathway);GO:0007257(activation of JUN kinase activity);GO:0031307(integral component of mitochondrial outer membrane);GO:0050689(negative regulation of defense response to virus by host);GO:0019789(SUMO transferase activity);GO:1901028(regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway);GO:0010637(negative regulation of mitochondrial fusion);GO:0071650(negative regulation of chemokine (C-C motif) ligand 5 production);GO:0090141(positive regulation of mitochondrial fission)","NA","NA","NA","mitochondrial E3 ubiquitin protein ligase 1 [Source:HGNC Symbol;Acc:HGNC:25762]",{"v":1.089991,"d":"1.09"},{"v":6.686655,"d":"6.69"},{"v":0.163009905550683,"d":"0.16"},{"v":-2.61696846015714,"d":"-2.62"},{"v":6.71901427305748e-05,"d":"0.00"},{"v":0.00299828115089772,"d":"0.00"},"down","yes"]
[31284,0,"chr11","+",65572462,65574190,"ENST00000449319",2,1337,"MSTRG.2549","FAM89B","GO:0005737(cytoplasm);GO:0009986(cell surface);GO:0030512(negative regulation of transforming growth factor beta receptor signaling pathway);GO:0001222(transcription corepressor binding);GO:0060392(negative regulation of SMAD protein import into nucleus)","NA","NA","NA","family with sequence similarity 89 member B [Source:HGNC Symbol;Acc:HGNC:16708]",{"v":1.048975,"d":"1.05"},{"v":6.611891,"d":"6.61"},{"v":0.158649772054621,"d":"0.16"},{"v":-2.65608264647079,"d":"-2.66"},{"v":6.73123310460894e-05,"d":"0.00"},{"v":0.00299828115089772,"d":"0.00"},"down","yes"]
[163268,0,"chr6","-",24804282,24936052,"ENST00000613507",23,5539,"MSTRG.12716","RIPOR2","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0007155(cell adhesion);GO:0007605(sensory perception of sound);GO:0048741(skeletal muscle fiber development);GO:0005886(plasma membrane);GO:0005856(cytoskeleton);GO:0042995(cell projection);GO:0005515(protein binding);GO:0007275(multicellular organism development);GO:0030154(cell differentiation);GO:0006935(chemotaxis);GO:2000114(regulation of establishment of cell polarity);GO:0030175(filopodium);GO:0032420(stereocilium);GO:0007517(muscle organ development);GO:0060171(stereocilium membrane);GO:0016324(apical plasma membrane);GO:0051491(positive regulation of filopodium assembly);GO:0007162(negative regulation of cell adhesion);GO:0009968(negative regulation of signal transduction);GO:1901741(positive regulation of myoblast fusion);GO:0071889(14-3-3 protein binding);GO:2000405(negative regulation of T cell migration);GO:0090023(positive regulation of neutrophil chemotaxis);GO:0045663(positive regulation of myoblast differentiation);GO:1990869(cellular response to chemokine);GO:0035024(negative regulation of Rho protein signal transduction);GO:1903904(negative regulation of establishment of T cell polarity);GO:1905872(negative regulation of protein localization to cell leading edge);GO:2000391(positive regulation of neutrophil extravasation);GO:2001107(negative regulation of Rho guanyl-nucleotide exchange factor activity)","NA","NA","NA","RHO family interacting cell polarization regulator 2 [Source:HGNC Symbol;Acc:HGNC:13872]",{"v":4.099873,"d":"4.10"},{"v":0.507548,"d":"0.51"},{"v":8.07780347868576,"d":"8.08"},{"v":3.01396304777729,"d":"3.01"},{"v":6.74264762557857e-05,"d":"0.00"},{"v":0.00299828115089772,"d":"0.00"},"up","yes"]
[24352,"j","chr10","+",128047561,128085855,"MSTRG.2045.6",19,3522,"MSTRG.2045","PTPRE","NA","NA","NA","NA","NA",{"v":4.300932,"d":"4.30"},{"v":0.530407,"d":"0.53"},{"v":8.10873913805813,"d":"8.11"},{"v":3.01947760116407,"d":"3.02"},{"v":6.89117276428998e-05,"d":"0.00"},{"v":0.00305745575470337,"d":"0.00"},"up","yes"]
[179222,0,"chr7","-",139572629,139777778,"ENST00000428878",15,3969,"MSTRG.14010","HIPK2","GO:0051091(positive regulation of sequence-specific DNA binding transcription factor activity);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0005515(protein binding);GO:0006974(cellular response to DNA damage stimulus);GO:0006915(apoptotic process);GO:0030218(erythrocyte differentiation);GO:0003714(transcription corepressor activity);GO:0005654(nucleoplasm);GO:0001654(eye development);GO:0045893(positive regulation of transcription, DNA-templated);GO:0030511(positive regulation of transforming growth factor beta receptor signaling pathway);GO:1901796(regulation of signal transduction by p53 class mediator);GO:0051726(regulation of cell cycle);GO:0016605(PML body);GO:0060395(SMAD protein signal transduction);GO:0090575(RNA polymerase II transcription factor complex);GO:0097193(intrinsic apoptotic signaling pathway);GO:0001102(RNA polymerase II activating transcription factor binding);GO:0045766(positive regulation of angiogenesis);GO:0032092(positive regulation of protein binding);GO:0071456(cellular response to hypoxia);GO:0046330(positive regulation of JNK cascade);GO:0018105(peptidyl-serine phosphorylation);GO:0042771(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator);GO:0018107(peptidyl-threonine phosphorylation);GO:0016604(nuclear body);GO:0030514(negative regulation of BMP signaling pathway);GO:0019048(modulation by virus of host morphology or physiology);GO:0046332(SMAD binding);GO:0006978(DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator);GO:0046790(virion binding);GO:0001105(RNA polymerase II transcription coactivator activity);GO:0030578(PML body organization);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0001934(positive regulation of protein phosphorylation);GO:0007179(transforming growth factor beta receptor signaling pathway);GO:0007224(smoothened signaling pathway);GO:0007628(adult walking behavior);GO:0008284(positive regulation of cell proliferation);GO:0008344(adult locomotory behavior);GO:0009952(anterior/posterior pattern specification);GO:0010842(retina layer formation);GO:0030182(neuron differentiation);GO:0043388(positive regulation of DNA binding);GO:0043524(negative regulation of neuron apoptotic process);GO:0048596(embryonic camera-type eye morphogenesis);GO:0050882(voluntary musculoskeletal movement);GO:0060059(embryonic retina morphogenesis in camera-type eye);GO:0060235(lens induction in camera-type eye);GO:0061072(iris morphogenesis)","04218(Cellular senescence)","K08826","EC:2.7.11.1","homeodomain interacting protein kinase 2 [Source:HGNC Symbol;Acc:HGNC:14402]",{"v":3.259393,"d":"3.26"},{"v":0.400627,"d":"0.40"},{"v":8.13572974362686,"d":"8.14"},{"v":3.02427175589095,"d":"3.02"},{"v":7.02655403041154e-05,"d":"0.00"},{"v":0.00311054700567748,"d":"0.00"},"up","yes"]
[57887,0,"chr14","+",92513793,92688041,"ENST00000555589",9,2814,"MSTRG.4626","RIN3","GO:0005737(cytoplasm);GO:0007165(signal transduction);GO:0043547(positive regulation of GTPase activity);GO:0005515(protein binding);GO:0031410(cytoplasmic vesicle);GO:0005096(GTPase activator activity);GO:0005768(endosome);GO:0005829(cytosol);GO:0006897(endocytosis);GO:0017112(Rab guanyl-nucleotide exchange factor activity);GO:0061024(membrane organization);GO:0005769(early endosome);GO:0017137(Rab GTPase binding)","NA","NA","NA","Ras and Rab interactor 3 [Source:HGNC Symbol;Acc:HGNC:18751]",{"v":3.820063,"d":"3.82"},{"v":0.464423,"d":"0.46"},{"v":8.22539581373016,"d":"8.23"},{"v":3.04008510435134,"d":"3.04"},{"v":7.0792476104509e-05,"d":"0.00"},{"v":0.00312687838650898,"d":"0.00"},"up","yes"]
[166999,"j","chr6","+",63635788,63714266,"MSTRG.13104.1",15,6797,"MSTRG.13104","PHF3","NA","NA","NA","NA","NA",{"v":14.936426,"d":"14.94"},{"v":1.899497,"d":"1.90"},{"v":7.86335856281953,"d":"7.86"},{"v":2.97514564161974,"d":"2.98"},{"v":7.15353222348594E-5,"d":"0.00"},{"v":0.00314981679388527,"d":"0.00"},"up","yes"]
[56403,0,"chr14","+",70907739,71110118,"ENST00000439984",34,6988,"ENSG00000100731","PCNX1","GO:0016020(membrane);GO:0016021(integral component of membrane)","NA","NA","NA","pecanex homolog 1 [Source:HGNC Symbol;Acc:HGNC:19740]",{"v":4.830516,"d":"4.83"},{"v":0.607257,"d":"0.61"},{"v":7.9546485260771,"d":"7.95"},{"v":2.99179818688721,"d":"2.99"},{"v":7.17335410944571e-05,"d":"0.00"},{"v":0.00314981679388527,"d":"0.00"},"up","yes"]
[43149,0,"chr12","-",56598369,56630211,"ENST00000549884",29,6050,"MSTRG.3470","BAZ2A","GO:0005634(nucleus);GO:0016607(nuclear speck);GO:0046872(metal ion binding);GO:0005829(cytosol);GO:0003677(DNA binding);GO:0003723(RNA binding);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0016569(covalent chromatin modification);GO:0005515(protein binding);GO:0005730(nucleolus);GO:0042393(histone binding);GO:0006338(chromatin remodeling);GO:0016922(ligand-dependent nuclear receptor binding);GO:0070577(lysine-acetylated histone binding);GO:0000183(chromatin silencing at rDNA);GO:0005677(chromatin silencing complex);GO:0033553(rDNA heterochromatin);GO:0001164(RNA polymerase I CORE element sequence-specific DNA binding);GO:0016575(histone deacetylation);GO:0006306(DNA methylation)","NA","NA","NA","bromodomain adjacent to zinc finger domain 2A [Source:HGNC Symbol;Acc:HGNC:962]",{"v":20.697767,"d":"20.70"},{"v":2.635201,"d":"2.64"},{"v":7.85434090226893,"d":"7.85"},{"v":2.97349021671318,"d":"2.97"},{"v":7.178933566011e-05,"d":"0.00"},{"v":0.00314981679388527,"d":"0.00"},"up","yes"]
[118486,0,"chr2","+",207529892,207603431,"ENST00000432329",9,7650,"MSTRG.9394","CREB1","GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0005515(protein binding);GO:0007623(circadian rhythm);GO:0048511(rhythmic process);GO:0030154(cell differentiation);GO:0045893(positive regulation of transcription, DNA-templated);GO:0042802(identical protein binding);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:0050821(protein stabilization);GO:0016032(viral process);GO:0007165(signal transduction);GO:0019899(enzyme binding);GO:0007411(axon guidance);GO:0000980(RNA polymerase II distal enhancer sequence-specific DNA binding);GO:0003712(transcription cofactor activity);GO:0001077(transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0001102(RNA polymerase II activating transcription factor binding);GO:0003705(transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding);GO:0006468(protein phosphorylation);GO:0010944(negative regulation of transcription by competitive promoter binding);GO:0001190(transcriptional activator activity, RNA polymerase II transcription factor binding);GO:0045600(positive regulation of fat cell differentiation);GO:0046889(positive regulation of lipid biosynthetic process);GO:0035497(cAMP response element binding);GO:0005719(nuclear euchromatin);GO:0010033(response to organic substance);GO:0033762(response to glucagon);GO:1990589(ATF4-CREB1 transcription factor complex);GO:0000975(regulatory region DNA binding);GO:0001225(RNA polymerase II transcription coactivator binding);GO:0003690(double-stranded DNA binding);GO:0008134(transcription factor binding);GO:0030544(Hsp70 protein binding);GO:0035035(histone acetyltransferase binding);GO:0043565(sequence-specific DNA binding);GO:0044212(transcription regulatory region DNA binding);GO:1990763(arrestin family protein binding);GO:0001666(response to hypoxia);GO:0006366(transcription from RNA polymerase II promoter);GO:0007179(transforming growth factor beta receptor signaling pathway);GO:0007409(axonogenesis);GO:0007568(aging);GO:0007595(lactation);GO:0007613(memory);GO:0008361(regulation of cell size);GO:0008542(visual learning);GO:0010629(negative regulation of gene expression);GO:0014823(response to activity);GO:0021983(pituitary gland development);GO:0030879(mammary gland development);GO:0032916(positive regulation of transforming growth factor beta3 production);GO:0033363(secretory granule organization);GO:0034670(chemotaxis to arachidonic acid);GO:0035094(response to nicotine);GO:0035729(cellular response to hepatocyte growth factor stimulus);GO:0036120(cellular response to platelet-derived growth factor stimulus);GO:0040018(positive regulation of multicellular organism growth);GO:0042493(response to drug);GO:0042752(regulation of circadian rhythm);GO:0042981(regulation of apoptotic process);GO:0043065(positive regulation of apoptotic process);GO:0045672(positive regulation of osteoclast differentiation);GO:0045899(positive regulation of RNA polymerase II transcriptional preinitiation complex assembly);GO:0046887(positive regulation of hormone secretion);GO:0048145(regulation of fibroblast proliferation);GO:0055025(positive regulation of cardiac muscle tissue development);GO:0060251(regulation of glial cell proliferation);GO:0060428(lung epithelium development);GO:0060430(lung saccule development);GO:0060509(Type I pneumocyte differentiation);GO:0071294(cellular response to zinc ion);GO:0071363(cellular response to growth factor stimulus);GO:0071398(cellular response to fatty acid);GO:0071560(cellular response to transforming growth factor beta stimulus);GO:1900273(positive regulation of long-term synaptic potentiation);GO:1901215(negative regulation of neuron death);GO:1902065(response to L-glutamate);GO:1990090(cellular response to nerve growth factor stimulus);GO:1990314(cellular response to insulin-like growth factor stimulus);GO:1990830(cellular response to leukemia inhibitory factor);GO:0000785(chromatin);GO:0000790(nuclear chromatin);GO:0005667(transcription factor complex);GO:0005739(mitochondrion);GO:0005759(mitochondrial matrix);GO:0030424(axon)","04668(TNF signaling pathway);04024(cAMP signaling pathway);04022(cGMP - PKG signaling pathway);04151(PI3K-Akt signaling pathway);04152(AMPK signaling pathway);04612(Antigen processing and presentation);04911(Insulin secretion);04922(Glucagon signaling pathway);04915(Estrogen signaling pathway);04926(Relaxin signaling pathway);04918(Thyroid hormone synthesis);04916(Melanogenesis);04924(Renin secretion);04925(Aldosterone synthesis and secretion);04927(Cortisol synthesis and secretion);04261(Adrenergic signaling in cardiomyocytes);04962(Vasopressin-regulated water reabsorption);04725(Cholinergic synapse);04728(Dopaminergic synapse);04380(Osteoclast differentiation);04211(Longevity regulating pathway - mammal);04710(Circadian rhythm);04713(Circadian entrainment);05203(Viral carcinogenesis);05215(Prostate cancer);05016(Huntington's disease);05030(Cocaine addiction);05031(Amphetamine addiction);05034(Alcoholism);04931(Insulin resistance);05152(Tuberculosis);05166(HTLV-I infection);05161(Hepatitis B);05167(Kaposi's sarcoma-associated herpesvirus infection);05165(Human papillomavirus infection)","K05870","NA","cAMP responsive element binding protein 1 [Source:HGNC Symbol;Acc:HGNC:2345]",{"v":4.317458,"d":"4.32"},{"v":0.544832,"d":"0.54"},{"v":7.92438403030659,"d":"7.92"},{"v":2.98629879759158,"d":"2.99"},{"v":7.27287648786362e-05,"d":"0.00"},{"v":0.00318397521995233,"d":"0.00"},"up","yes"]
[178986,"j","chr7","-",135165798,135170790,"MSTRG.13988.7",3,2461,"MSTRG.13988","C7orf49","NA","NA","NA","NA","NA",{"v":5.412732,"d":"5.41"},{"v":0.665254,"d":"0.67"},{"v":8.13633890213362,"d":"8.14"},{"v":3.0243797728833,"d":"3.02"},{"v":7.37956514053503e-05,"d":"0.00"},{"v":0.00322355044152113,"d":"0.00"},"up","yes"]
[62327,0,"chr15","-",48988770,49046433,"ENST00000261847",17,6779,"MSTRG.5061","SECISBP2L","GO:0003723(RNA binding);GO:0005515(protein binding);GO:0003730(mRNA 3'-UTR binding);GO:0030529(intracellular ribonucleoprotein complex);GO:0043021(ribonucleoprotein complex binding);GO:0035368(selenocysteine insertion sequence binding);GO:0001514(selenocysteine incorporation)","NA","NA","NA","SECIS binding protein 2 like [Source:HGNC Symbol;Acc:HGNC:28997]",{"v":1.502546,"d":"1.50"},{"v":0.18454,"d":"0.18"},{"v":8.14211553050829,"d":"8.14"},{"v":3.02540369238297,"d":"3.03"},{"v":7.52028169607574e-05,"d":"0.00"},{"v":3.27778269167283E-3,"d":"0.00"},"up","yes"]
[55788,0,"chr14","+",63852983,64226432,"ENST00000358025",116,21842,"ENSG00000054654","SYNE2","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0031965(nuclear membrane);GO:0051015(actin filament binding);GO:0003779(actin binding);GO:0005739(mitochondrion);GO:0045111(intermediate filament cytoskeleton);GO:0005886(plasma membrane);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0016235(aggresome);GO:0034993(LINC complex);GO:0030054(cell junction);GO:0005654(nucleoplasm);GO:0005925(focal adhesion);GO:0090286(cytoskeletal anchoring at nuclear membrane);GO:0005635(nuclear envelope);GO:0070062(extracellular exosome);GO:0016529(sarcoplasmic reticulum);GO:0030335(positive regulation of cell migration);GO:0033017(sarcoplasmic reticulum membrane);GO:0030018(Z disc);GO:0031527(filopodium membrane);GO:0031258(lamellipodium membrane);GO:0051642(centrosome localization);GO:0005640(nuclear outer membrane);GO:0031981(nuclear lumen);GO:0007097(nuclear migration);GO:0031022(nuclear migration along microfilament);GO:0006998(nuclear envelope organization);GO:0007163(establishment or maintenance of cell polarity);GO:0010761(fibroblast migration);GO:0021817(nucleokinesis involved in cell motility in cerebral cortex radial glia guided migration);GO:0034504(protein localization to nucleus);GO:1902017(regulation of cilium assembly);GO:0030016(myofibril)","NA","NA","NA","spectrin repeat containing nuclear envelope protein 2 [Source:HGNC Symbol;Acc:HGNC:17084]",{"v":0.254333,"d":"0.25"},{"v":1.51887,"d":"1.52"},{"v":0.167448827088559,"d":"0.17"},{"v":-2.57820782430374,"d":"-2.58"},{"v":7.5623215910763E-5,"d":"0.00"},{"v":0.00328277472479991,"d":"0.00"},"down","yes"]
[53147,0,"chr14","-",23059059,23095383,"ENST00000555053",19,4173,"MSTRG.4182","ACIN1","GO:0003676(nucleic acid binding);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0005886(plasma membrane);GO:0003723(RNA binding);GO:0006397(mRNA processing);GO:0008380(RNA splicing);GO:0005634(nucleus);GO:0016607(nuclear speck);GO:0005515(protein binding);GO:0006915(apoptotic process);GO:0030218(erythrocyte differentiation);GO:0016887(ATPase activity);GO:0019899(enzyme binding);GO:0061574(ASAP complex);GO:0097194(execution phase of apoptosis);GO:0030263(apoptotic chromosome condensation);GO:0045657(positive regulation of monocyte differentiation);GO:0005730(nucleolus)","03040(Spliceosome);03013(RNA transport);03015(mRNA surveillance pathway)","K12875","NA","apoptotic chromatin condensation inducer 1 [Source:HGNC Symbol;Acc:HGNC:17066]",{"v":3.856361,"d":"3.86"},{"v":0.480827,"d":"0.48"},{"v":8.02026716469749,"d":"8.02"},{"v":3.003650295379,"d":"3.00"},{"v":7.56491446588215e-05,"d":"0.00"},{"v":0.00328277472479991,"d":"0.00"},"up","yes"]
[77501,"j","chr17","-",1568808,1629114,"MSTRG.6286.1",14,9553,"MSTRG.6286","SLC43A2","NA","NA","NA","NA","NA",{"v":10.114508,"d":"10.11"},{"v":1.296233,"d":"1.30"},{"v":7.80300146655733,"d":"7.80"},{"v":2.96402917115351,"d":"2.96"},{"v":7.58352565207495e-05,"d":"0.00"},{"v":0.00328365001320042,"d":"0.00"},"up","yes"]
[184870,0,"chr8","-",76980258,77000226,"ENST00000357039",4,4317,"MSTRG.14408","PEX2","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0046872(metal ion binding);GO:0005515(protein binding);GO:0005777(peroxisome);GO:0005778(peroxisomal membrane);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0061630(ubiquitin protein ligase activity);GO:0016567(protein ubiquitination);GO:0031648(protein destabilization);GO:0007031(peroxisome organization);GO:0016558(protein import into peroxisome matrix);GO:0005779(integral component of peroxisomal membrane);GO:0050680(negative regulation of epithelial cell proliferation);GO:0006635(fatty acid beta-oxidation);GO:0048147(negative regulation of fibroblast proliferation);GO:0000038(very long-chain fatty acid metabolic process);GO:0016593(Cdc73/Paf1 complex)","04146(Peroxisome)","K06664","NA","peroxisomal biogenesis factor 2 [Source:HGNC Symbol;Acc:HGNC:9717]",{"v":0.918512,"d":"0.92"},{"v":5.478689,"d":"5.48"},{"v":0.167651786768696,"d":"0.17"},{"v":-2.57646023598113,"d":"-2.58"},{"v":7.90744300809152e-05,"d":"0.00"},{"v":0.00341642974332129,"d":"0.00"},"down","yes"]
[96013,0,"chr19","-",8580242,8608265,"ENST00000270328",25,4194,"ENSG00000142303","ADAMTS10","GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0016787(hydrolase activity);GO:0008233(peptidase activity);GO:0006508(proteolysis);GO:0005576(extracellular region);GO:0005578(proteinaceous extracellular matrix);GO:0004222(metalloendopeptidase activity);GO:0008237(metallopeptidase activity);GO:0005515(protein binding);GO:0003674(molecular_function);GO:0008150(biological_process);GO:0031012(extracellular matrix);GO:0001527(microfibril)","NA","NA","NA","ADAM metallopeptidase with thrombospondin type 1 motif 10 [Source:HGNC Symbol;Acc:HGNC:13201]",{"v":0.20098,"d":"0.20"},{"v":1.268621,"d":"1.27"},{"v":0.158423989513022,"d":"0.16"},{"v":-2.65813728137044,"d":"-2.66"},{"v":7.98552423475626e-05,"d":"0.00"},{"v":0.00344138696570107,"d":"0.00"},"down","yes"]
[122479,0,"chr20","-",23079349,23086340,"ENST00000246006",2,6708,"MSTRG.9621","CD93","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0030246(carbohydrate binding);GO:0005509(calcium ion binding);GO:0007155(cell adhesion);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0004872(receptor activity);GO:0016032(viral process);GO:0031012(extracellular matrix);GO:0043312(neutrophil degranulation);GO:0035579(specific granule membrane);GO:0070821(tertiary granule membrane);GO:0042116(macrophage activation);GO:0030667(secretory granule membrane);GO:0006909(phagocytosis);GO:0016337(single organismal cell-cell adhesion);GO:0101003(ficolin-1-rich granule membrane);GO:0001849(complement component C1q binding);GO:0009986(cell surface);GO:0031410(cytoplasmic vesicle)","NA","NA","NA","CD93 molecule [Source:HGNC Symbol;Acc:HGNC:15855]",{"v":2.282617,"d":"2.28"},{"v":13.392887,"d":"13.39"},{"v":0.170435022710189,"d":"0.17"},{"v":-2.55270626930868,"d":"-2.55"},{"v":7.99998991420302e-05,"d":"0.00"},{"v":0.00344138696570107,"d":"0.00"},"down","yes"]
[45435,0,"chr12","-",95973847,95996344,"ENST00000538703",20,2637,"MSTRG.3623","HAL","GO:0005737(cytoplasm);GO:0003824(catalytic activity);GO:0016829(lyase activity);GO:0005829(cytosol);GO:0006548(histidine catabolic process);GO:0016841(ammonia-lyase activity);GO:0006547(histidine metabolic process);GO:0019556(histidine catabolic process to glutamate and formamide);GO:0019557(histidine catabolic process to glutamate and formate);GO:0004397(histidine ammonia-lyase activity)","00340(Histidine metabolism)","K01745","EC:4.3.1.3","histidine ammonia-lyase [Source:HGNC Symbol;Acc:HGNC:4806]",{"v":3.468549,"d":"3.47"},{"v":0.425577,"d":"0.43"},{"v":8.15022663348818,"d":"8.15"},{"v":3.0268401769466,"d":"3.03"},{"v":8.16912560263591e-05,"d":"0.00"},{"v":0.003506521853036,"d":"0.00"},"up","yes"]
[71731,0,"chr16","+",30064274,30070414,"ENST00000563060",9,1550,"MSTRG.5821","ALDOA","GO:0070062(extracellular exosome);GO:0008360(regulation of cell shape);GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005829(cytosol);GO:0003824(catalytic activity);GO:0004332(fructose-bisphosphate aldolase activity);GO:0016829(lyase activity);GO:0006096(glycolytic process);GO:0005515(protein binding);GO:0005615(extracellular space);GO:0005576(extracellular region);GO:0045296(cadherin binding);GO:0031430(M band);GO:0031674(I band);GO:0043312(neutrophil degranulation);GO:0015629(actin cytoskeleton);GO:0002576(platelet degranulation);GO:0034774(secretory granule lumen);GO:1904813(ficolin-1-rich granule lumen);GO:0031093(platelet alpha granule lumen);GO:1904724(tertiary granule lumen);GO:0051289(protein homotetramerization);GO:0006094(gluconeogenesis);GO:0061621(canonical glycolysis);GO:0042802(identical protein binding);GO:0003779(actin binding);GO:0006754(ATP biosynthetic process);GO:0046716(muscle cell cellular homeostasis);GO:0008092(cytoskeletal protein binding);GO:0015631(tubulin binding);GO:0070061(fructose binding);GO:0006000(fructose metabolic process);GO:0006941(striated muscle contraction);GO:0007015(actin filament organization);GO:0030388(fructose 1,6-bisphosphate metabolic process);GO:0016021(integral component of membrane)","00010(Glycolysis / Gluconeogenesis);00030(Pentose phosphate pathway);00051(Fructose and mannose metabolism);04066(HIF-1 signaling pathway)","K01623","EC:4.1.2.13","aldolase, fructose-bisphosphate A [Source:HGNC Symbol;Acc:HGNC:414]",{"v":3.079264,"d":"3.08"},{"v":18.164482,"d":"18.16"},{"v":0.169521156727728,"d":"0.17"},{"v":-2.56046275780046,"d":"-2.56"},{"v":8.36855284629661e-05,"d":"0.00"},{"v":0.00357872626003335,"d":"0.00"},"down","yes"]
[57059,0,"chr14","+",76151936,76214343,"ENST00000261530",10,14007,"ENSG00000089916","GPATCH2L","GO:0005515(protein binding)","NA","NA","NA","G-patch domain containing 2 like [Source:HGNC Symbol;Acc:HGNC:20210]",{"v":4.010535,"d":"4.01"},{"v":0.518824,"d":"0.52"},{"v":7.73004911106657,"d":"7.73"},{"v":2.95047758000615,"d":"2.95"},{"v":8.37904911189211e-05,"d":"0.00"},{"v":0.00357872626003335,"d":"0.00"},"up","yes"]
[111731,0,"chr2","+",85577491,85582031,"ENST00000263864",3,774,"MSTRG.8872","VAMP8","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016192(vesicle-mediated transport);GO:0006810(transport);GO:0005737(cytoplasm);GO:0015031(protein transport);GO:0005765(lysosomal membrane);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0048471(perinuclear region of cytoplasm);GO:0065009(regulation of molecular function);GO:0006914(autophagy);GO:0005764(lysosome);GO:0006906(vesicle fusion);GO:0005768(endosome);GO:0031902(late endosome membrane);GO:0070062(extracellular exosome);GO:0061024(membrane organization);GO:0002479(antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent);GO:0031901(early endosome membrane);GO:0055037(recycling endosome);GO:0043312(neutrophil degranulation);GO:0035579(specific granule membrane);GO:0070821(tertiary granule membrane);GO:0000149(SNARE binding);GO:0005484(SNAP receptor activity);GO:0006892(post-Golgi vesicle-mediated transport);GO:0030670(phagocytic vesicle membrane);GO:0031201(SNARE complex);GO:0030667(secretory granule membrane);GO:0031982(vesicle);GO:0035577(azurophil granule membrane);GO:0019869(chloride channel inhibitor activity);GO:1903076(regulation of protein localization to plasma membrane);GO:0030665(clathrin-coated vesicle membrane);GO:0008021(synaptic vesicle);GO:1903595(positive regulation of histamine secretion by mast cell);GO:0016240(autophagosome docking);GO:0097352(autophagosome maturation);GO:0070254(mucus secretion);GO:0055038(recycling endosome membrane);GO:0005769(early endosome);GO:1903531(negative regulation of secretion by cell);GO:0046718(viral entry into host cell);GO:0098594(mucin granule)","04130(SNARE interactions in vesicular transport);04140(Autophagy - animal);04611(Platelet activation)","K08512","NA","vesicle associated membrane protein 8 [Source:HGNC Symbol;Acc:HGNC:12647]",{"v":13.515248,"d":"13.52"},{"v":79.072853,"d":"79.07"},{"v":0.170921466561982,"d":"0.17"},{"v":-2.54859449390816,"d":"-2.55"},{"v":8.39159583917259e-05,"d":"0.00"},{"v":0.00357872626003335,"d":"0.00"},"down","yes"]
[108257,0,"chr2","+",27435582,27442255,"ENST00000460499",11,2561,"MSTRG.8575","NRBP1","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0004672(protein kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0042803(protein homodimerization activity);GO:0042995(cell projection);GO:0005515(protein binding);GO:0004674(protein serine/threonine kinase activity);GO:0035556(intracellular signal transduction);GO:0005654(nucleoplasm);GO:0030027(lamellipodium);GO:0005938(cell cortex);GO:0005829(cytosol);GO:0012505(endomembrane system);GO:0006888(ER to Golgi vesicle-mediated transport);GO:0006367(transcription initiation from RNA polymerase II promoter)","NA","NA","NA","nuclear receptor binding protein 1 [Source:HGNC Symbol;Acc:HGNC:7993]",{"v":0.41107,"d":"0.41"},{"v":2.535702,"d":"2.54"},{"v":0.162112898124464,"d":"0.16"},{"v":-2.62492921488984,"d":"-2.62"},{"v":8.43715487910441e-05,"d":"0.00"},{"v":3.59041765048856E-3,"d":"0.00"},"down","yes"]
[60649,0,"chr15","-",32765545,33194733,"ENST00000616417",21,13529,"ENSG00000248905","FMN1","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0003779(actin binding);GO:0005886(plasma membrane);GO:0008017(microtubule binding);GO:0030054(cell junction);GO:0045010(actin nucleation);GO:0005884(actin filament);GO:0005912(adherens junction);GO:0017124(SH3 domain binding);GO:0001822(kidney development);GO:0010467(gene expression);GO:0030838(positive regulation of actin filament polymerization);GO:0035136(forelimb morphogenesis);GO:0035137(hindlimb morphogenesis);GO:0048705(skeletal system morphogenesis);GO:0048813(dendrite morphogenesis);GO:0051127(positive regulation of actin nucleation);GO:0051894(positive regulation of focal adhesion assembly);GO:0060173(limb development);GO:0072092(ureteric bud invasion);GO:0015630(microtubule cytoskeleton)","NA","NA","NA","formin 1 [Source:HGNC Symbol;Acc:HGNC:3768]",{"v":0.067825,"d":"0.07"},{"v":0.425286,"d":"0.43"},{"v":0.159480914020212,"d":"0.16"},{"v":-2.64854431601304,"d":"-2.65"},{"v":8.55673542802305e-05,"d":"0.00"},{"v":0.00363349100106696,"d":"0.00"},"down","yes"]
[169119,0,"chr6","-",130144318,130222954,"ENST00000439090",12,2093,"MSTRG.13274","SAMD3","GO:0005515(protein binding)","NA","NA","NA","sterile alpha motif domain containing 3 [Source:HGNC Symbol;Acc:HGNC:21574]",{"v":9.790339,"d":"9.79"},{"v":1.25412,"d":"1.25"},{"v":7.80654084138679,"d":"7.81"},{"v":2.96468341693485,"d":"2.96"},{"v":8.69720968731002e-05,"d":"0.00"},{"v":3.68523308977496E-3,"d":"0.00"},"up","yes"]
[16788,0,"chr1","-",228393673,228405904,"ENST00000493030",5,5774,"MSTRG.1438","TRIM11","GO:0005634(nucleus);GO:0005829(cytosol);GO:0005737(cytoplasm);GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0016740(transferase activity);GO:0016567(protein ubiquitination);GO:0005622(intracellular);GO:0005515(protein binding);GO:0045087(innate immune response);GO:0051607(defense response to virus);GO:0046598(positive regulation of viral entry into host cell);GO:0046597(negative regulation of viral entry into host cell);GO:0032897(negative regulation of viral transcription);GO:1902187(negative regulation of viral release from host cell);GO:0004842(ubiquitin-protein transferase activity);GO:0008134(transcription factor binding);GO:0019904(protein domain specific binding);GO:0061630(ubiquitin protein ligase activity);GO:0045892(negative regulation of transcription, DNA-templated);GO:0050768(negative regulation of neurogenesis)","NA","NA","NA","tripartite motif containing 11 [Source:HGNC Symbol;Acc:HGNC:16281]",{"v":0.22043,"d":"0.22"},{"v":1.339802,"d":"1.34"},{"v":0.164524310308538,"d":"0.16"},{"v":-2.60362732083398,"d":"-2.60"},{"v":8.72479605772315e-05,"d":"0.00"},{"v":3.68902274338089E-3,"d":"0.00"},"down","yes"]
[84508,0,"chr17","-",45508109,45550335,"ENST00000581296",14,5372,"ENSG00000214425","LRRC37A4P","NA","NA","NA","NA","leucine rich repeat containing 37 member A4, pseudogene [Source:HGNC Symbol;Acc:HGNC:25479]",{"v":1.450289,"d":"1.45"},{"v":0.177754,"d":"0.18"},{"v":8.15896688682111,"d":"8.16"},{"v":3.02838648533162,"d":"3.03"},{"v":8.75072126944656e-05,"d":"0.00"},{"v":3.69209536204283E-3,"d":"0.00"},"up","yes"]
[147808,0,"chr4","-",67493405,67545503,"ENST00000510189",14,2917,"MSTRG.11639","CENPC","GO:0005634(nucleus);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0003677(DNA binding);GO:0051301(cell division);GO:0005694(chromosome);GO:0007049(cell cycle);GO:0016604(nuclear body);GO:0000776(kinetochore);GO:0051382(kinetochore assembly);GO:0007059(chromosome segregation);GO:0000775(chromosome, centromeric region);GO:0000777(condensed chromosome kinetochore);GO:0034080(CENP-A containing nucleosome assembly);GO:0019237(centromeric DNA binding);GO:0007062(sister chromatid cohesion);GO:0000278(mitotic cell cycle);GO:0000778(condensed nuclear chromosome kinetochore);GO:0000780(condensed nuclear chromosome, centromeric region);GO:0051315(attachment of mitotic spindle microtubules to kinetochore);GO:0051455(attachment of spindle microtubules to kinetochore involved in homologous chromosome segregation);GO:0005721(pericentric heterochromatin);GO:0031618(nuclear pericentric heterochromatin)","NA","NA","NA","centromere protein C [Source:HGNC Symbol;Acc:HGNC:1854]",{"v":3.41583,"d":"3.42"},{"v":0.427942,"d":"0.43"},{"v":7.98199288688654,"d":"7.98"},{"v":2.99674899319921,"d":"3.00"},{"v":8.88880261067535e-05,"d":"0.00"},{"v":0.0037384936375569,"d":"0.00"},"up","yes"]
[179723,0,"chr7","-",143811968,143836933,"ENST00000481651",2,2106,"ENSG00000253882","AC099548.2","NA","NA","NA","NA","NA",{"v":0.407358,"d":"0.41"},{"v":2.568403,"d":"2.57"},{"v":0.158603614775407,"d":"0.16"},{"v":-2.6565024426404,"d":"-2.66"},{"v":8.8984763659253e-05,"d":"0.00"},{"v":0.0037384936375569,"d":"0.00"},"down","yes"]
[188163,0,"chr8","-",143915153,143976734,"ENST00000436759",33,14787,"MSTRG.14615","PLEC","GO:0003723(RNA binding);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0003779(actin binding);GO:0005925(focal adhesion);GO:0045111(intermediate filament cytoskeleton);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0008092(cytoskeletal protein binding);GO:0030054(cell junction);GO:0045296(cadherin binding);GO:0070062(extracellular exosome);GO:0042383(sarcolemma);GO:0031012(extracellular matrix);GO:0005886(plasma membrane);GO:0008307(structural constituent of muscle);GO:0030506(ankyrin binding);GO:0031581(hemidesmosome assembly);GO:0030056(hemidesmosome);GO:0043034(costamere);GO:0016528(sarcoplasm);GO:0005903(brush border);GO:0043292(contractile fiber)","NA","NA","NA","plectin [Source:HGNC Symbol;Acc:HGNC:9069]",{"v":7.038825,"d":"7.04"},{"v":0.921835,"d":"0.92"},{"v":7.6356669035131,"d":"7.64"},{"v":2.9327541683349,"d":"2.93"},{"v":8.95092187867815e-05,"d":"0.00"},{"v":0.00375073187849051,"d":"0.00"},"up","yes"]
[31285,0,"chr11","+",65572528,65574192,"ENST00000530349",2,1263,"MSTRG.2549","FAM89B","GO:0005737(cytoplasm);GO:0009986(cell surface);GO:0030512(negative regulation of transforming growth factor beta receptor signaling pathway);GO:0001222(transcription corepressor binding);GO:0060392(negative regulation of SMAD protein import into nucleus)","NA","NA","NA","family with sequence similarity 89 member B [Source:HGNC Symbol;Acc:HGNC:16708]",{"v":2.336779,"d":"2.34"},{"v":13.756466,"d":"13.76"},{"v":0.169867682586502,"d":"0.17"},{"v":-2.55751668972864,"d":"-2.56"},{"v":8.96551535539728e-05,"d":"0.00"},{"v":0.00375073187849051,"d":"0.00"},"down","yes"]
[105161,0,"chr19","+",53333749,53354869,"ENST00000458035",4,4311,"ENSG00000213799","ZNF845","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0005622(intracellular)","NA","NA","NA","zinc finger protein 845 [Source:HGNC Symbol;Acc:HGNC:25112]",{"v":1.501132,"d":"1.50"},{"v":0.182101,"d":"0.18"},{"v":8.24340338603302,"d":"8.24"},{"v":3.04324009401371,"d":"3.04"},{"v":9.02904701067942e-05,"d":"0.00"},{"v":0.00376934139762288,"d":"0.00"},"up","yes"]
[118780,0,"chr2","+",215312072,215349763,"ENST00000443953",16,2187,"MSTRG.9403","ATIC","GO:0016020(membrane);GO:0016740(transferase activity);GO:0016787(hydrolase activity);GO:0003824(catalytic activity);GO:0042803(protein homodimerization activity);GO:0008152(metabolic process);GO:0006164(purine nucleotide biosynthetic process);GO:0006189('de novo' IMP biosynthetic process);GO:0005829(cytosol);GO:0045296(cadherin binding);GO:0070062(extracellular exosome);GO:0003937(IMP cyclohydrolase activity);GO:0004643(phosphoribosylaminoimidazolecarboxamide formyltransferase activity);GO:0006139(nucleobase-containing compound metabolic process);GO:0009168(purine ribonucleoside monophosphate biosynthetic process);GO:0003360(brainstem development);GO:0009116(nucleoside metabolic process);GO:0009259(ribonucleotide metabolic process);GO:0010035(response to inorganic substance);GO:0021549(cerebellum development);GO:0021987(cerebral cortex development);GO:0031100(animal organ regeneration);GO:0046452(dihydrofolate metabolic process);GO:0046654(tetrahydrofolate biosynthetic process);GO:0005739(mitochondrion)","00230(Purine metabolism);00670(One carbon pool by folate);01523(Antifolate resistance)","NA","NA","5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase [Source:HGNC Symbol;Acc:HGNC:794]",{"v":3.624649,"d":"3.62"},{"v":0.446135,"d":"0.45"},{"v":8.12455646833358,"d":"8.12"},{"v":3.02228905630214,"d":"3.02"},{"v":9.13919039495115e-05,"d":"0.00"},{"v":3.80729051653249E-3,"d":"0.00"},"up","yes"]
[125086,0,"chr20","+",59019254,59026654,"ENST00000217133",4,3496,"MSTRG.9855","TUBB1","GO:0005737(cytoplasm);GO:0005525(GTP binding);GO:0000166(nucleotide binding);GO:0003924(GTPase activity);GO:0015630(microtubule cytoskeleton);GO:0005856(cytoskeleton);GO:0005200(structural constituent of cytoskeleton);GO:0005874(microtubule);GO:0007017(microtubule-based process);GO:0070062(extracellular exosome);GO:0051225(spindle assembly)","04145(Phagosome);04540(Gap junction);05130(Pathogenic Escherichia coli infection)","K07375","NA","tubulin beta 1 class VI [Source:HGNC Symbol;Acc:HGNC:16257]",{"v":15.550496,"d":"15.55"},{"v":88.920532,"d":"88.92"},{"v":0.174880825049495,"d":"0.17"},{"v":-2.51555598242909,"d":"-2.52"},{"v":9.58633476125605e-05,"d":"0.00"},{"v":3.98517630789359E-3,"d":"0.00"},"down","yes"]
[134969,0,"chr3","+",39406735,39412434,"ENST00000443003",7,1032,"MSTRG.10823","RPSA","GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0006412(translation);GO:0007155(cell adhesion);GO:0030529(intracellular ribonucleoprotein complex);GO:0005622(intracellular);GO:0003735(structural constituent of ribosome);GO:0005840(ribosome);GO:0005886(plasma membrane);GO:0015935(small ribosomal subunit);GO:0005515(protein binding);GO:0005055(laminin receptor activity);GO:0043236(laminin binding);GO:0000028(ribosomal small subunit assembly);GO:0022627(cytosolic small ribosomal subunit);GO:0043022(ribosome binding);GO:0046718(viral entry into host cell);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0016032(viral process);GO:0006413(translational initiation);GO:0006364(rRNA processing);GO:0001618(virus receptor activity);GO:0030686(90S preribosome);GO:0000184(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay);GO:0019083(viral transcription);GO:0006614(SRP-dependent cotranslational protein targeting to membrane);GO:0000447(endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA));GO:0000461(endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA));GO:0006407(rRNA export from nucleus);GO:0016337(single organismal cell-cell adhesion);GO:0030855(epithelial cell differentiation);GO:0005604(basement membrane);GO:0031012(extracellular matrix);GO:0043025(neuronal cell body)","03010(Ribosome)","K02998","NA","ribosomal protein SA [Source:HGNC Symbol;Acc:HGNC:6502]",{"v":41.460064,"d":"41.46"},{"v":236.90062,"d":"236.90"},{"v":0.175010365105841,"d":"0.18"},{"v":-2.51448772572139,"d":"-2.51"},{"v":9.65525776824788e-05,"d":"0.00"},{"v":0.00400541385153227,"d":"0.00"},"down","yes"]
[165299,0,"chr6","+",33420255,33451842,"ENST00000449372",18,3930,"ENSG00000197283","SYNGAP1","GO:0007165(signal transduction);GO:0043547(positive regulation of GTPase activity);GO:0043087(regulation of GTPase activity);GO:0005096(GTPase activator activity);GO:0005737(cytoplasm);GO:0007265(Ras protein signal transduction);GO:0007389(pattern specification process);GO:0008542(visual learning);GO:0016358(dendrite development);GO:0043113(receptor clustering);GO:0043408(regulation of MAPK cascade);GO:0043524(negative regulation of neuron apoptotic process);GO:0048169(regulation of long-term neuronal synaptic plasticity);GO:0050771(negative regulation of axonogenesis);GO:0050803(regulation of synapse structure or activity);GO:0014069(postsynaptic density);GO:0016020(membrane);GO:0043198(dendritic shaft);GO:0005829(cytosol);GO:0000165(MAPK cascade);GO:0017124(SH3 domain binding);GO:0046580(negative regulation of Ras protein signal transduction);GO:0031235(intrinsic component of the cytoplasmic side of the plasma membrane);GO:0048167(regulation of synaptic plasticity)","04014(Ras signaling pathway)","NA","NA","synaptic Ras GTPase activating protein 1 [Source:HGNC Symbol;Acc:HGNC:11497]",{"v":1.977003,"d":"1.98"},{"v":0.247416,"d":"0.25"},{"v":7.99060287127752,"d":"7.99"},{"v":2.99830435504198,"d":"3.00"},{"v":9.69362737311087e-05,"d":"0.00"},{"v":0.00401273805984009,"d":"0.00"},"up","yes"]
[97666,0,"chr19","-",14736079,14776756,"ENST00000596991",20,2596,"MSTRG.7912","ADGRE2","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0004930(G-protein coupled receptor activity);GO:0007186(G-protein coupled receptor signaling pathway);GO:0005509(calcium ion binding);GO:0007155(cell adhesion);GO:0005886(plasma membrane);GO:0042995(cell projection);GO:0004871(signal transducer activity);GO:0007165(signal transduction);GO:0004888(transmembrane signaling receptor activity);GO:0007166(cell surface receptor signaling pathway);GO:0006954(inflammatory response);GO:0032587(ruffle membrane);GO:0016477(cell migration);GO:0035374(chondroitin sulfate binding);GO:0071621(granulocyte chemotaxis);GO:0043304(regulation of mast cell degranulation);GO:0031256(leading edge membrane)","NA","NA","NA","adhesion G protein-coupled receptor E2 [Source:HGNC Symbol;Acc:HGNC:3337]",{"v":0.940124,"d":"0.94"},{"v":5.521508,"d":"5.52"},{"v":0.170265804196969,"d":"0.17"},{"v":-2.55413937842168,"d":"-2.55"},{"v":9.71347043998082e-05,"d":"0.00"},{"v":0.00401273805984009,"d":"0.00"},"down","yes"]
[44652,0,"chr12","-",76355836,76559809,"ENST00000393250",23,3157,"MSTRG.3569","OSBPL8","GO:0051897(positive regulation of protein kinase B signaling);GO:0032148(activation of protein kinase B activity);GO:0006810(transport);GO:0005634(nucleus);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0006869(lipid transport);GO:0008289(lipid binding);GO:0005829(cytosol);GO:0031965(nuclear membrane);GO:0001786(phosphatidylserine binding);GO:0005548(phospholipid transporter activity);GO:0036150(phosphatidylserine acyl-chain remodeling);GO:0045444(fat cell differentiation);GO:0015914(phospholipid transport);GO:0070273(phosphatidylinositol-4-phosphate binding);GO:0015485(cholesterol binding);GO:2001275(positive regulation of glucose import in response to insulin stimulus);GO:0010891(negative regulation of sequestering of triglyceride);GO:0030336(negative regulation of cell migration);GO:0046628(positive regulation of insulin receptor signaling pathway);GO:0090204(protein localization to nuclear pore)","NA","NA","NA","oxysterol binding protein like 8 [Source:HGNC Symbol;Acc:HGNC:16396]",{"v":24.941769,"d":"24.94"},{"v":3.304692,"d":"3.30"},{"v":7.54738081491407,"d":"7.55"},{"v":2.91597606948119,"d":"2.92"},{"v":1.0013257495636E-4,"d":"0.00"},{"v":0.00412796540257595,"d":"0.00"},"up","yes"]
[121089,0,"chr2","+",241315100,241354024,"ENST00000391973",13,3701,"MSTRG.9533","SEPT2","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005525(GTP binding);GO:0000166(nucleotide binding);GO:0005730(nucleolus);GO:0005829(cytosol);GO:0051301(cell division);GO:0005694(chromosome);GO:0005886(plasma membrane);GO:0015629(actin cytoskeleton);GO:0005856(cytoskeleton);GO:0042995(cell projection);GO:0005515(protein binding);GO:0007049(cell cycle);GO:0030154(cell differentiation);GO:0007283(spermatogenesis);GO:0005819(spindle);GO:0030496(midbody);GO:0000775(chromosome, centromeric region);GO:0000776(kinetochore);GO:0000777(condensed chromosome kinetochore);GO:0007224(smoothened signaling pathway);GO:0060271(cilium assembly);GO:0045296(cadherin binding);GO:0070062(extracellular exosome);GO:0005938(cell cortex);GO:0032154(cleavage furrow);GO:0060170(ciliary membrane);GO:0031105(septin complex);GO:0097227(sperm annulus);GO:0005930(axoneme);GO:0032391(photoreceptor connecting cilium);GO:0097730(non-motile cilium);GO:0031175(neuron projection development);GO:0000145(exocyst);GO:0048471(perinuclear region of cytoplasm)","05100(Bacterial invasion of epithelial cells)","K16942","NA","septin 2 [Source:HGNC Symbol;Acc:HGNC:7729]",{"v":9.156289,"d":"9.16"},{"v":1.202092,"d":"1.20"},{"v":7.61696192970255,"d":"7.62"},{"v":2.92921568499808,"d":"2.93"},{"v":1.01156521874079E-4,"d":"0.00"},{"v":0.00416150780632905,"d":"0.00"},"up","yes"]
[84431,0,"chr17","+",45231427,45239054,"ENST00000592006",11,888,"MSTRG.6920","FMNL1","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005829(cytosol);GO:0003779(actin binding);GO:0005886(plasma membrane);GO:0030036(actin cytoskeleton organization);GO:0042995(cell projection);GO:0005515(protein binding);GO:0008360(regulation of cell shape);GO:0031410(cytoplasmic vesicle);GO:0007010(cytoskeleton organization);GO:0016043(cellular component organization);GO:0017048(Rho GTPase binding);GO:0003674(molecular_function);GO:0051015(actin filament binding);GO:0070062(extracellular exosome);GO:0005938(cell cortex);GO:0030866(cortical actin cytoskeleton organization);GO:0045335(phagocytic vesicle);GO:0005522(profilin binding);GO:0032794(GTPase activating protein binding);GO:0048365(Rac GTPase binding);GO:0006929(substrate-dependent cell migration);GO:0009987(cellular process);GO:0051014(actin filament severing);GO:0032059(bleb);GO:0016021(integral component of membrane)","NA","NA","NA","formin like 1 [Source:HGNC Symbol;Acc:HGNC:1212]",{"v":8.809152,"d":"8.81"},{"v":1.105914,"d":"1.11"},{"v":7.96549460446291,"d":"7.97"},{"v":2.99376394633961,"d":"2.99"},{"v":0.000101642575922939,"d":"0.00"},{"v":0.00417282840739236,"d":"0.00"},"up","yes"]
[89917,0,"chr17","+",82458185,82488255,"ENST00000390006",11,1766,"MSTRG.7368","NARF","GO:0005634(nucleus);GO:0005730(nucleolus);GO:0055114(oxidation-reduction process);GO:0003954(NADH dehydrogenase activity);GO:0005521(lamin binding);GO:0005638(lamin filament);GO:0005652(nuclear lamina);GO:0031981(nuclear lumen)","NA","NA","NA","nuclear prelamin A recognition factor [Source:HGNC Symbol;Acc:HGNC:29916]",{"v":0.550796,"d":"0.55"},{"v":3.307278,"d":"3.31"},{"v":0.166540581106275,"d":"0.17"},{"v":-2.58605433184189,"d":"-2.59"},{"v":1.02893475262759E-4,"d":"0.00"},{"v":0.00421543703623079,"d":"0.00"},"down","yes"]
[23199,"j","chr10","-",103088060,103181329,"MSTRG.1950.7",20,3552,"MSTRG.1950","NT5C2","NA","NA","NA","NA","NA",{"v":0.951403,"d":"0.95"},{"v":5.497447,"d":"5.50"},{"v":0.173062696193342,"d":"0.17"},{"v":-2.53063331077619,"d":"-2.53"},{"v":1.03950342230102E-4,"d":"0.00"},{"v":0.00424993671911004,"d":"0.00"},"down","yes"]
[199648,0,"chrX","-",119786506,119791595,"ENST00000468844",2,1915,"MSTRG.15420","RPL39","GO:0003723(RNA binding);GO:0006412(translation);GO:0030529(intracellular ribonucleoprotein complex);GO:0005622(intracellular);GO:0003735(structural constituent of ribosome);GO:0005840(ribosome);GO:0005615(extracellular space);GO:0005829(cytosol);GO:0002227(innate immune response in mucosa);GO:0019731(antibacterial humoral response);GO:0050830(defense response to Gram-positive bacterium);GO:0061844(antimicrobial humoral immune response mediated by antimicrobial peptide);GO:0006413(translational initiation);GO:0006364(rRNA processing);GO:0000184(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay);GO:0019083(viral transcription);GO:0006614(SRP-dependent cotranslational protein targeting to membrane);GO:0022625(cytosolic large ribosomal subunit)","03010(Ribosome)","NA","NA","ribosomal protein L39 [Source:HGNC Symbol;Acc:HGNC:10350]",{"v":0.5559,"d":"0.56"},{"v":3.32634,"d":"3.33"},{"v":0.167120619058785,"d":"0.17"},{"v":-2.58103835323743,"d":"-2.58"},{"v":1.05185233691896E-4,"d":"0.00"},{"v":0.00429155753462934,"d":"0.00"},"down","yes"]
[49034,"j","chr13","-",21373571,21459330,"MSTRG.3896.4",12,4304,"MSTRG.3896","ZDHHC20","NA","NA","NA","NA","NA",{"v":5.651381,"d":"5.65"},{"v":0.746923,"d":"0.75"},{"v":7.56621633019736,"d":"7.57"},{"v":2.91957202593014,"d":"2.92"},{"v":1.1008565553658E-4,"d":"0.00"},{"v":0.00448225298715608,"d":"0.00"},"up","yes"]
[124655,0,"chr20","-",50934945,50958521,"ENST00000371584",10,1073,"MSTRG.9831","DPM1","GO:0005634(nucleus);GO:0016020(membrane);GO:0016740(transferase activity);GO:0016757(transferase activity, transferring glycosyl groups);GO:0005783(endoplasmic reticulum);GO:0005515(protein binding);GO:0006486(protein glycosylation);GO:0006506(GPI anchor biosynthetic process);GO:0005789(endoplasmic reticulum membrane);GO:0004169(dolichyl-phosphate-mannose-protein mannosyltransferase activity);GO:0004582(dolichyl-phosphate beta-D-mannosyltransferase activity);GO:0018279(protein N-linked glycosylation via asparagine);GO:0019348(dolichol metabolic process);GO:0035268(protein mannosylation);GO:0035269(protein O-linked mannosylation);GO:0033185(dolichol-phosphate-mannose synthase complex);GO:0097502(mannosylation);GO:0005537(mannose binding);GO:0043178(alcohol binding);GO:0019673(GDP-mannose metabolic process);GO:0043231(intracellular membrane-bounded organelle)","00510(N-Glycan biosynthesis)","K00721","EC:2.4.1.83","dolichyl-phosphate mannosyltransferase subunit 1, catalytic [Source:HGNC Symbol;Acc:HGNC:3005]",{"v":0.766603,"d":"0.77"},{"v":4.679583,"d":"4.68"},{"v":0.163818656491401,"d":"0.16"},{"v":-2.60982842719462,"d":"-2.61"},{"v":1.10372977881889E-4,"d":"0.00"},{"v":0.0044847237912255,"d":"0.00"},"down","yes"]
[187172,0,"chr8","+",127736084,127741434,"ENST00000377970",3,2351,"MSTRG.14560","MYC","GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0006355(regulation of transcription, DNA-templated);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0045727(positive regulation of translation);GO:0003729(mRNA binding);GO:0005515(protein binding);GO:0008150(biological_process);GO:0005635(nuclear envelope);GO:0005791(rough endoplasmic reticulum);GO:0071074(eukaryotic initiation factor eIF2 binding);GO:0044195(nucleoplasmic reticulum);GO:0046983(protein dimerization activity);GO:0006366(transcription from RNA polymerase II promoter);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0006974(cellular response to DNA damage stimulus);GO:0006879(cellular iron ion homeostasis);GO:0045893(positive regulation of transcription, DNA-templated);GO:0005730(nucleolus);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0015671(oxygen transport);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0005829(cytosol);GO:0016579(protein deubiquitination);GO:0007050(cell cycle arrest);GO:0043234(protein complex);GO:0043066(negative regulation of apoptotic process);GO:0008134(transcription factor binding);GO:0000165(MAPK cascade);GO:0010332(response to gamma radiation);GO:1904837(beta-catenin-TCF complex assembly);GO:0006338(chromatin remodeling);GO:0000082(G1/S transition of mitotic cell cycle);GO:0070491(repressing transcription factor binding);GO:0070888(E-box binding);GO:0000981(RNA polymerase II transcription factor activity, sequence-specific DNA binding);GO:0035690(cellular response to drug);GO:0032403(protein complex binding);GO:0007219(Notch signaling pathway);GO:0043280(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process);GO:0001077(transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0051973(positive regulation of telomerase activity);GO:0048146(positive regulation of fibroblast proliferation);GO:0060070(canonical Wnt signaling pathway);GO:0010468(regulation of gene expression);GO:0050679(positive regulation of epithelial cell proliferation);GO:0002053(positive regulation of mesenchymal cell proliferation);GO:0042493(response to drug);GO:0008284(positive regulation of cell proliferation);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0071456(cellular response to hypoxia);GO:0033613(activating transcription factor binding);GO:0001658(branching involved in ureteric bud morphogenesis);GO:0006112(energy reserve metabolic process);GO:0010628(positive regulation of gene expression);GO:0032204(regulation of telomere maintenance);GO:0032873(negative regulation of stress-activated MAPK cascade);GO:0032986(protein-DNA complex disassembly);GO:0034644(cellular response to UV);GO:0044346(fibroblast apoptotic process);GO:0045656(negative regulation of monocyte differentiation);GO:0048147(negative regulation of fibroblast proliferation);GO:0051276(chromosome organization);GO:0051782(negative regulation of cell division);GO:0070371(ERK1 and ERK2 cascade);GO:0070848(response to growth factor);GO:0090096(positive regulation of metanephric cap mesenchymal cell proliferation);GO:2000573(positive regulation of DNA biosynthetic process);GO:2001022(positive regulation of response to DNA damage stimulus)","04010(MAPK signaling pathway);04012(ErbB signaling pathway);04310(Wnt signaling pathway);04350(TGF-beta signaling pathway);04390(Hippo signaling pathway);04630(Jak-STAT signaling pathway);04151(PI3K-Akt signaling pathway);04110(Cell cycle);04218(Cellular senescence);04550(Signaling pathways regulating pluripotency of stem cells);04919(Thyroid hormone signaling pathway);05200(Pathways in cancer);05230(Central carbon metabolism in cancer);05202(Transcriptional misregulation in cancers);05206(MicroRNAs in cancer);05205(Proteoglycans in cancer);05210(Colorectal cancer);05225(Hepatocellular carcinoma);05226(Gastric cancer);05216(Thyroid cancer);05221(Acute myeloid leukemia);05220(Chronic myeloid leukemia);05219(Bladder cancer);05213(Endometrial cancer);05224(Breast cancer);05222(Small cell lung cancer);05166(HTLV-I infection);05161(Hepatitis B);05167(Kaposi's sarcoma-associated herpesvirus infection);05169(Epstein-Barr virus infection)","NA","NA","MYC proto-oncogene, bHLH transcription factor [Source:HGNC Symbol;Acc:HGNC:7553]",{"v":0.498812,"d":"0.50"},{"v":2.957974,"d":"2.96"},{"v":0.168632990012759,"d":"0.17"},{"v":-2.56804129364891,"d":"-2.57"},{"v":1.10652152668683E-4,"d":"0.00"},{"v":0.0044868540922293,"d":"0.00"},"down","yes"]
[68036,0,"chr16","-",1809103,1826841,"ENST00000397353",10,1257,"MSTRG.5524","HAGH","GO:0004416(hydroxyacylglutathione hydrolase activity);GO:0019243(methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione);GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0016787(hydrolase activity);GO:0005739(mitochondrion);GO:0005515(protein binding);GO:0005759(mitochondrial matrix);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0006090(pyruvate metabolic process);GO:0006750(glutathione biosynthetic process)","00620(Pyruvate metabolism)","K01069","EC:3.1.2.6","hydroxyacylglutathione hydrolase [Source:HGNC Symbol;Acc:HGNC:4805]",{"v":21.867371,"d":"21.87"},{"v":2.909874,"d":"2.91"},{"v":7.51488586791043,"d":"7.51"},{"v":2.90975119342308,"d":"2.91"},{"v":0.0001113585008393,"d":"0.00"},{"v":0.00449891491878735,"d":"0.00"},"up","yes"]
[134953,0,"chr3","-",39263495,39281735,"ENST00000358309",2,3151,"MSTRG.10821","CX3CR1","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0004930(G-protein coupled receptor activity);GO:0007186(G-protein coupled receptor signaling pathway);GO:0007155(cell adhesion);GO:0005886(plasma membrane);GO:0004871(signal transducer activity);GO:0007165(signal transduction);GO:0006935(chemotaxis);GO:0070098(chemokine-mediated signaling pathway);GO:0005515(protein binding);GO:0016032(viral process);GO:0005887(integral component of plasma membrane);GO:0016495(C-X3-C chemokine receptor activity);GO:0009611(response to wounding);GO:0004950(chemokine receptor activity);GO:0006968(cellular defense response);GO:0019960(C-X3-C chemokine binding);GO:0004896(cytokine receptor activity);GO:0001774(microglial cell activation);GO:0002052(positive regulation of neuroblast proliferation);GO:0002282(microglial cell activation involved in immune response);GO:0002881(negative regulation of chronic inflammatory response to non-antigenic stimulus);GO:0007613(memory);GO:0016525(negative regulation of angiogenesis);GO:0019221(cytokine-mediated signaling pathway);GO:0021795(cerebral cortex cell migration);GO:0030336(negative regulation of cell migration);GO:0045766(positive regulation of angiogenesis);GO:0048246(macrophage chemotaxis);GO:0071222(cellular response to lipopolysaccharide);GO:0071560(cellular response to transforming growth factor beta stimulus);GO:1900272(negative regulation of long-term synaptic potentiation);GO:2001240(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand);GO:0032809(neuronal cell body membrane);GO:0043005(neuron projection);GO:0048471(perinuclear region of cytoplasm)","04060(Cytokine-cytokine receptor interaction);04062(Chemokine signaling pathway)","K04192","NA","C-X3-C motif chemokine receptor 1 [Source:HGNC Symbol;Acc:HGNC:2558]",{"v":0.918582,"d":"0.92"},{"v":5.279749,"d":"5.28"},{"v":0.173982134377979,"d":"0.17"},{"v":-2.52298892655819,"d":"-2.52"},{"v":1.11404301101971E-4,"d":"0.00"},{"v":0.00449891491878735,"d":"0.00"},"down","yes"]
[176911,"j","chr7","-",100466507,100479169,"MSTRG.13816.4",4,2668,"MSTRG.13816","TSC22D4","NA","NA","NA","NA","NA",{"v":3.122407,"d":"3.12"},{"v":0.402001,"d":"0.40"},{"v":7.76716227074062,"d":"7.77"},{"v":2.95738760690772,"d":"2.96"},{"v":1.11728259504865E-4,"d":"0.00"},{"v":0.00450280814477039,"d":"0.00"},"up","yes"]
[187171,0,"chr8","+",127736069,127741434,"ENST00000621592",3,2366,"MSTRG.14560","MYC","GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0006355(regulation of transcription, DNA-templated);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0045727(positive regulation of translation);GO:0003729(mRNA binding);GO:0005515(protein binding);GO:0008150(biological_process);GO:0005635(nuclear envelope);GO:0005791(rough endoplasmic reticulum);GO:0071074(eukaryotic initiation factor eIF2 binding);GO:0044195(nucleoplasmic reticulum);GO:0046983(protein dimerization activity);GO:0006366(transcription from RNA polymerase II promoter);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0006974(cellular response to DNA damage stimulus);GO:0006879(cellular iron ion homeostasis);GO:0045893(positive regulation of transcription, DNA-templated);GO:0005730(nucleolus);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0015671(oxygen transport);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0005829(cytosol);GO:0016579(protein deubiquitination);GO:0007050(cell cycle arrest);GO:0043234(protein complex);GO:0043066(negative regulation of apoptotic process);GO:0008134(transcription factor binding);GO:0000165(MAPK cascade);GO:0010332(response to gamma radiation);GO:1904837(beta-catenin-TCF complex assembly);GO:0006338(chromatin remodeling);GO:0000082(G1/S transition of mitotic cell cycle);GO:0070491(repressing transcription factor binding);GO:0070888(E-box binding);GO:0000981(RNA polymerase II transcription factor activity, sequence-specific DNA binding);GO:0035690(cellular response to drug);GO:0032403(protein complex binding);GO:0007219(Notch signaling pathway);GO:0043280(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process);GO:0001077(transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0051973(positive regulation of telomerase activity);GO:0048146(positive regulation of fibroblast proliferation);GO:0060070(canonical Wnt signaling pathway);GO:0010468(regulation of gene expression);GO:0050679(positive regulation of epithelial cell proliferation);GO:0002053(positive regulation of mesenchymal cell proliferation);GO:0042493(response to drug);GO:0008284(positive regulation of cell proliferation);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0071456(cellular response to hypoxia);GO:0033613(activating transcription factor binding);GO:0001658(branching involved in ureteric bud morphogenesis);GO:0006112(energy reserve metabolic process);GO:0010628(positive regulation of gene expression);GO:0032204(regulation of telomere maintenance);GO:0032873(negative regulation of stress-activated MAPK cascade);GO:0032986(protein-DNA complex disassembly);GO:0034644(cellular response to UV);GO:0044346(fibroblast apoptotic process);GO:0045656(negative regulation of monocyte differentiation);GO:0048147(negative regulation of fibroblast proliferation);GO:0051276(chromosome organization);GO:0051782(negative regulation of cell division);GO:0070371(ERK1 and ERK2 cascade);GO:0070848(response to growth factor);GO:0090096(positive regulation of metanephric cap mesenchymal cell proliferation);GO:2000573(positive regulation of DNA biosynthetic process);GO:2001022(positive regulation of response to DNA damage stimulus)","04010(MAPK signaling pathway);04012(ErbB signaling pathway);04310(Wnt signaling pathway);04350(TGF-beta signaling pathway);04390(Hippo signaling pathway);04630(Jak-STAT signaling pathway);04151(PI3K-Akt signaling pathway);04110(Cell cycle);04218(Cellular senescence);04550(Signaling pathways regulating pluripotency of stem cells);04919(Thyroid hormone signaling pathway);05200(Pathways in cancer);05230(Central carbon metabolism in cancer);05202(Transcriptional misregulation in cancers);05206(MicroRNAs in cancer);05205(Proteoglycans in cancer);05210(Colorectal cancer);05225(Hepatocellular carcinoma);05226(Gastric cancer);05216(Thyroid cancer);05221(Acute myeloid leukemia);05220(Chronic myeloid leukemia);05219(Bladder cancer);05213(Endometrial cancer);05224(Breast cancer);05222(Small cell lung cancer);05166(HTLV-I infection);05161(Hepatitis B);05167(Kaposi's sarcoma-associated herpesvirus infection);05169(Epstein-Barr virus infection)","K04377","NA","MYC proto-oncogene, bHLH transcription factor [Source:HGNC Symbol;Acc:HGNC:7553]",{"v":0.496019,"d":"0.50"},{"v":2.936713,"d":"2.94"},{"v":0.168902783486163,"d":"0.17"},{"v":-2.56573499120873,"d":"-2.57"},{"v":1.1210305109308E-4,"d":"0.00"},{"v":0.0045087300305485,"d":"0.00"},"down","yes"]
[105530,0,"chr19","+",54449224,54461400,"ENST00000376514",14,5146,"MSTRG.8421","LENG8","GO:0005515(protein binding)","NA","NA","NA","leukocyte receptor cluster member 8 [Source:HGNC Symbol;Acc:HGNC:15500]",{"v":0.179095,"d":"0.18"},{"v":1.080067,"d":"1.08"},{"v":0.165818416820438,"d":"0.17"},{"v":-2.59232384450754,"d":"-2.59"},{"v":1.12445427656796E-4,"d":"0.00"},{"v":0.00451332682043139,"d":"0.00"},"down","yes"]
[147246,0,"chr4","-",48497363,48780299,"ENST00000358350",64,11706,"MSTRG.11602","FRYL","GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0005938(cell cortex);GO:0000902(cell morphogenesis);GO:0031175(neuron projection development);GO:0090527(actin filament reorganization);GO:0030427(site of polarized growth)","NA","NA","NA","FRY like transcription coactivator [Source:HGNC Symbol;Acc:HGNC:29127]",{"v":5.493967,"d":"5.49"},{"v":0.738652,"d":"0.74"},{"v":7.43782863919681,"d":"7.44"},{"v":2.89488150995194,"d":"2.89"},{"v":1.13101311959432E-4,"d":"0.00"},{"v":0.00453046307905516,"d":"0.00"},"up","yes"]
[128560,0,"chr22","+",19717220,19724216,"ENST00000455843",12,4113,"MSTRG.10135","SEPT5","GO:0005737(cytoplasm);GO:0005525(GTP binding);GO:0000166(nucleotide binding);GO:0051301(cell division);GO:0005886(plasma membrane);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0008021(synaptic vesicle);GO:0007049(cell cycle);GO:0017157(regulation of exocytosis);GO:0003924(GTPase activity);GO:0005198(structural molecule activity);GO:0000910(cytokinesis);GO:2000300(regulation of synaptic vesicle exocytosis);GO:0016080(synaptic vesicle targeting);GO:0005938(cell cortex);GO:0043195(terminal bouton);GO:0043679(axon terminus);GO:0045202(synapse)","05012(Parkinson's disease)","NA","NA","septin 5 [Source:HGNC Symbol;Acc:HGNC:9164]",{"v":7.04593,"d":"7.05"},{"v":0.942986,"d":"0.94"},{"v":7.47193489617025,"d":"7.47"},{"v":2.9014818847342,"d":"2.90"},{"v":0.000114960296693524,"d":"0.00"},{"v":4.5956249514575E-3,"d":"0.00"},"up","yes"]
[62410,0,"chr15","-",49858239,50113316,"ENST00000559726",29,5783,"ENSG00000104043","ATP8B4","GO:0016021(integral component of membrane);GO:0005524(ATP binding);GO:0000287(magnesium ion binding);GO:0004012(phospholipid-translocating ATPase activity);GO:0015914(phospholipid transport);GO:0045332(phospholipid translocation);GO:0006810(transport);GO:0016020(membrane);GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0016787(hydrolase activity);GO:0005794(Golgi apparatus);GO:0005886(plasma membrane);GO:0006869(lipid transport);GO:0043312(neutrophil degranulation);GO:0035579(specific granule membrane);GO:0070821(tertiary granule membrane);GO:0007030(Golgi organization)","NA","NA","NA","ATPase phospholipid transporting 8B4 (putative) [Source:HGNC Symbol;Acc:HGNC:13536]",{"v":0.193216,"d":"0.19"},{"v":1.141919,"d":"1.14"},{"v":0.169202894425962,"d":"0.17"},{"v":-2.56317384712533,"d":"-2.56"},{"v":1.15628541809365E-4,"d":"0.00"},{"v":0.00461301932524943,"d":"0.00"},"down","yes"]
[124667,0,"chr20","-",51386957,51542719,"ENST00000371564",11,7525,"MSTRG.9832","NFATC2","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0006355(regulation of transcription, DNA-templated);GO:0006366(transcription from RNA polymerase II promoter);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0005515(protein binding);GO:0006974(cellular response to DNA damage stimulus);GO:0038095(Fc-epsilon receptor signaling pathway);GO:0030890(positive regulation of B cell proliferation);GO:0050853(B cell receptor signaling pathway);GO:0016477(cell migration);GO:0045893(positive regulation of transcription, DNA-templated);GO:0042493(response to drug);GO:0045589(regulation of regulatory T cell differentiation);GO:0000976(transcription regulatory region sequence-specific DNA binding);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:0000981(RNA polymerase II transcription factor activity, sequence-specific DNA binding);GO:0001077(transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0001078(transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0003682(chromatin binding);GO:0008134(transcription factor binding);GO:0043565(sequence-specific DNA binding);GO:0044212(transcription regulatory region DNA binding);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0001816(cytokine production);GO:0010628(positive regulation of gene expression);GO:0014904(myotube cell development);GO:0033173(calcineurin-NFAT signaling cascade);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:1901741(positive regulation of myoblast fusion);GO:0000790(nuclear chromatin);GO:0005667(transcription factor complex);GO:0030529(intracellular ribonucleoprotein complex);GO:0044798(nuclear transcription factor complex)","04310(Wnt signaling pathway);04370(VEGF signaling pathway);04022(cGMP - PKG signaling pathway);04218(Cellular senescence);04650(Natural killer cell mediated cytotoxicity);04660(T cell receptor signaling pathway);04658(Th1 and Th2 cell differentiation);04659(Th17 cell differentiation);04662(B cell receptor signaling pathway);04921(Oxytocin signaling pathway);04360(Axon guidance);04380(Osteoclast differentiation);05166(HTLV-I infection);05161(Hepatitis B);05167(Kaposi's sarcoma-associated herpesvirus infection)","K17332","NA","nuclear factor of activated T-cells 2 [Source:HGNC Symbol;Acc:HGNC:7776]",{"v":6.996237,"d":"7.00"},{"v":0.943182,"d":"0.94"},{"v":7.41769563032373,"d":"7.42"},{"v":2.89097107107206,"d":"2.89"},{"v":0.000116654703256689,"d":"0.00"},{"v":0.00464459410069089,"d":"0.00"},"up","yes"]
[161044,0,"chr5","+",171387851,171407125,"ENST00000393820",10,1598,"MSTRG.12532","NPM1","GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0006334(nucleosome assembly);GO:0042803(protein homodimerization activity);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0007165(signal transduction);GO:0006281(DNA repair);GO:0004860(protein kinase inhibitor activity);GO:0003713(transcription coactivator activity);GO:0045893(positive regulation of transcription, DNA-templated);GO:0005654(nucleoplasm);GO:0006886(intracellular protein transport);GO:0045727(positive regulation of translation);GO:0005730(nucleolus);GO:0005925(focal adhesion);GO:0005813(centrosome);GO:0005815(microtubule organizing center);GO:0019843(rRNA binding);GO:0047485(protein N-terminus binding);GO:0000055(ribosomal large subunit export from nucleus);GO:0000056(ribosomal small subunit export from nucleus);GO:0006407(rRNA export from nucleus);GO:0006884(cell volume homeostasis);GO:0006913(nucleocytoplasmic transport);GO:0008104(protein localization);GO:0008284(positive regulation of cell proliferation);GO:0010608(posttranscriptional regulation of gene expression);GO:0010629(negative regulation of gene expression);GO:0010824(regulation of centrosome duplication);GO:0010825(positive regulation of centrosome duplication);GO:0016049(cell growth);GO:0031328(positive regulation of cellular biosynthetic process);GO:0031398(positive regulation of protein ubiquitination);GO:0031647(regulation of protein stability);GO:0042273(ribosomal large subunit biogenesis);GO:0042274(ribosomal small subunit biogenesis);GO:0043066(negative regulation of apoptotic process);GO:0043516(regulation of DNA damage response, signal transduction by p53 class mediator);GO:0045860(positive regulation of protein kinase activity);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0048025(negative regulation of mRNA splicing, via spliceosome);GO:0050821(protein stabilization);GO:0051260(protein homooligomerization);GO:0051726(regulation of cell cycle);GO:1904751(positive regulation of protein localization to nucleolus);GO:0001652(granular component);GO:0005829(cytosol);GO:0015934(large ribosomal subunit);GO:0015935(small ribosomal subunit);GO:0016607(nuclear speck);GO:0006977(DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest);GO:0019901(protein kinase binding);GO:0008285(negative regulation of cell proliferation);GO:0016032(viral process);GO:0034080(CENP-A containing nucleosome assembly);GO:0007098(centrosome cycle);GO:0051092(positive regulation of NF-kappaB transcription factor activity);GO:0008134(transcription factor binding);GO:0042393(histone binding);GO:0046982(protein heterodimerization activity);GO:0043234(protein complex);GO:0030957(Tat protein binding);GO:0051082(unfolded protein binding);GO:0030529(intracellular ribonucleoprotein complex);GO:0007569(cell aging);GO:0006950(response to stress);GO:0051059(NF-kappaB binding);GO:0032993(protein-DNA complex);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0033613(activating transcription factor binding);GO:0001047(core promoter binding);GO:0034644(cellular response to UV);GO:0001105(RNA polymerase II transcription coactivator activity);GO:0043023(ribosomal large subunit binding);GO:0043024(ribosomal small subunit binding);GO:0010826(negative regulation of centrosome duplication);GO:0032071(regulation of endodeoxyribonuclease activity);GO:0042255(ribosome assembly);GO:0044387(negative regulation of protein kinase activity by regulation of protein phosphorylation);GO:0046599(regulation of centriole replication);GO:0051259(protein oligomerization);GO:0060699(regulation of endoribonuclease activity);GO:0060735(regulation of eIF2 alpha phosphorylation by dsRNA);GO:1902751(positive regulation of cell cycle G2/M phase transition);GO:0031616(spindle pole centrosome)","NA","NA","NA","nucleophosmin [Source:HGNC Symbol;Acc:HGNC:7910]",{"v":18.310764,"d":"18.31"},{"v":101.915886,"d":"101.92"},{"v":0.179665454706443,"d":"0.18"},{"v":-2.47661505451331,"d":"-2.48"},{"v":1.18518649924643E-4,"d":"0.00"},{"v":4.70933141507797E-3,"d":"0.00"},"down","yes"]
[81881,0,"chr17","+",31937067,32000649,"ENST00000580398",15,3977,"MSTRG.6649","SUZ12","GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0005730(nucleolus);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0016569(covalent chromatin modification);GO:0005515(protein binding);GO:0016604(nuclear body);GO:0005654(nucleoplasm);GO:0035098(ESC/E(Z) complex);GO:0045596(negative regulation of cell differentiation);GO:0035064(methylated histone binding);GO:0045814(negative regulation of gene expression, epigenetic);GO:0042054(histone methyltransferase activity);GO:0031490(chromatin DNA binding);GO:0046976(histone methyltransferase activity (H3-K27 specific));GO:0070734(histone H3-K27 methylation);GO:0000979(RNA polymerase II core promoter sequence-specific DNA binding);GO:0003682(chromatin binding);GO:0003723(RNA binding);GO:0043565(sequence-specific DNA binding);GO:1990841(promoter-specific chromatin binding);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0008284(positive regulation of cell proliferation);GO:0016571(histone methylation);GO:0016574(histone ubiquitination);GO:0001739(sex chromatin);GO:0016586(RSC complex);GO:0032993(protein-DNA complex)","NA","NA","NA","SUZ12 polycomb repressive complex 2 subunit [Source:HGNC Symbol;Acc:HGNC:17101]",{"v":2.077029,"d":"2.08"},{"v":0.267291,"d":"0.27"},{"v":7.77066567897909,"d":"7.77"},{"v":2.95803819330806,"d":"2.96"},{"v":1.18943839786467E-4,"d":"0.00"},{"v":0.00471675491321566,"d":"0.00"},"up","yes"]
[103560,0,"chr19","-",48615366,48619177,"ENST00000549273",6,1036,"MSTRG.8290","RPL18","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0006412(translation);GO:0005783(endoplasmic reticulum);GO:0005730(nucleolus);GO:0005829(cytosol);GO:0030529(intracellular ribonucleoprotein complex);GO:0005622(intracellular);GO:0003735(structural constituent of ribosome);GO:0005840(ribosome);GO:0005925(focal adhesion);GO:0006413(translational initiation);GO:0003723(RNA binding);GO:0006364(rRNA processing);GO:0000184(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay);GO:0019083(viral transcription);GO:0006614(SRP-dependent cotranslational protein targeting to membrane);GO:0022625(cytosolic large ribosomal subunit)","03010(Ribosome)","NA","NA","ribosomal protein L18 [Source:HGNC Symbol;Acc:HGNC:10310]",{"v":10.702188,"d":"10.70"},{"v":1.394469,"d":"1.39"},{"v":7.67474070775327,"d":"7.67"},{"v":2.94011800964144,"d":"2.94"},{"v":0.000119185285925058,"d":"0.00"},{"v":0.0047168768757701,"d":"0.00"},"up","yes"]
[28807,0,"chr11","-",47358181,47378487,"ENST00000533968",4,1290,"MSTRG.2367","SPI1","GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0006355(regulation of transcription, DNA-templated);GO:0006366(transcription from RNA polymerase II promoter);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0043565(sequence-specific DNA binding);GO:0005515(protein binding);GO:0001047(core promoter binding);GO:1902036(regulation of hematopoietic stem cell differentiation);GO:0000981(RNA polymerase II transcription factor activity, sequence-specific DNA binding);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0045893(positive regulation of transcription, DNA-templated);GO:0045892(negative regulation of transcription, DNA-templated);GO:0000790(nuclear chromatin);GO:0001085(RNA polymerase II transcription factor binding);GO:0000980(RNA polymerase II distal enhancer sequence-specific DNA binding);GO:0003705(transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding);GO:1902895(positive regulation of pri-miRNA transcription from RNA polymerase II promoter);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0043966(histone H3 acetylation);GO:0045814(negative regulation of gene expression, epigenetic);GO:0051525(NFAT protein binding);GO:0044027(hypermethylation of CpG island);GO:0045646(regulation of erythrocyte differentiation);GO:0090241(negative regulation of histone H4 acetylation);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:0000979(RNA polymerase II core promoter sequence-specific DNA binding);GO:0000982(transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0001077(transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0001078(transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0001205(transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding);GO:0001944(vasculature development);GO:0002320(lymphoid progenitor cell differentiation);GO:0002573(myeloid leukocyte differentiation);GO:0030098(lymphocyte differentiation);GO:0030218(erythrocyte differentiation);GO:0030225(macrophage differentiation);GO:0030851(granulocyte differentiation);GO:0035019(somatic stem cell population maintenance);GO:0043011(myeloid dendritic cell differentiation);GO:0045347(negative regulation of MHC class II biosynthetic process);GO:0060033(anatomical structure regression);GO:0071361(cellular response to ethanol);GO:1902262(apoptotic process involved in blood vessel morphogenesis);GO:0016020(membrane);GO:0016021(integral component of membrane)","04380(Osteoclast differentiation);05200(Pathways in cancer);05202(Transcriptional misregulation in cancers);05221(Acute myeloid leukemia);05166(HTLV-I infection);05169(Epstein-Barr virus infection)","NA","NA","Spi-1 proto-oncogene [Source:HGNC Symbol;Acc:HGNC:11241]",{"v":9.268776,"d":"9.27"},{"v":1.216012,"d":"1.22"},{"v":7.6222734644066,"d":"7.62"},{"v":2.93022136866779,"d":"2.93"},{"v":1.20009201302909E-4,"d":"0.00"},{"v":0.00474000414247899,"d":"0.00"},"up","yes"]
[26503,"j","chr11","+",9384628,9445661,"MSTRG.2220.2",24,3638,"MSTRG.2220","IPO7","NA","NA","NA","NA","NA",{"v":3.550627,"d":"3.55"},{"v":0.468803,"d":"0.47"},{"v":7.57381458736399,"d":"7.57"},{"v":2.92102010340286,"d":"2.92"},{"v":0.0001210815785969,"d":"0.00"},{"v":0.00477283322166424,"d":"0.00"},"up","yes"]
[21324,0,"chr10","+",73785662,73801792,"ENST00000605216",26,6004,"MSTRG.1812","ZSWIM8","GO:0008270(zinc ion binding);GO:0046872(metal ion binding)","NA","NA","NA","zinc finger SWIM-type containing 8 [Source:HGNC Symbol;Acc:HGNC:23528]",{"v":2.971551,"d":"2.97"},{"v":0.395929,"d":"0.40"},{"v":7.50526230713082,"d":"7.51"},{"v":2.90790249457531,"d":"2.91"},{"v":1.21399986415829E-4,"d":"0.00"},{"v":0.00477587063856146,"d":"0.00"},"up","yes"]
[139644,0,"chr3","-",121769994,121835034,"ENST00000349820",12,1919,"ENSG00000173226","IQCB1","GO:0005737(cytoplasm);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0060271(cilium assembly);GO:0005516(calmodulin binding);GO:0005813(centrosome);GO:0005815(microtubule organizing center);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0030030(cell projection organization);GO:0005814(centriole);GO:0097711(ciliary basal body docking);GO:0019899(enzyme binding);GO:0045494(photoreceptor cell maintenance);GO:0048496(maintenance of animal organ identity);GO:0001750(photoreceptor outer segment);GO:0032391(photoreceptor connecting cilium)","NA","NA","NA","IQ motif containing B1 [Source:HGNC Symbol;Acc:HGNC:28949]",{"v":0.379605,"d":"0.38"},{"v":2.301299,"d":"2.30"},{"v":0.16495248987637,"d":"0.16"},{"v":-2.59987754005102,"d":"-2.60"},{"v":1.21748983108941E-4,"d":"0.00"},{"v":0.00478009697968198,"d":"0.00"},"down","yes"]
[15548,0,"chr1","+",207496228,207640208,"ENST00000400960",39,6959,"MSTRG.1357","CR1","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0002376(immune system process);GO:0045087(innate immune response);GO:0030449(regulation of complement activation);GO:0005886(plasma membrane);GO:0005887(integral component of plasma membrane);GO:0046718(viral entry into host cell);GO:0070062(extracellular exosome);GO:0016032(viral process);GO:0002430(complement receptor mediated signaling pathway);GO:0043312(neutrophil degranulation);GO:0006958(complement activation, classical pathway);GO:0009986(cell surface);GO:0030667(secretory granule membrane);GO:0001618(virus receptor activity);GO:0101003(ficolin-1-rich granule membrane);GO:0045589(regulation of regulatory T cell differentiation);GO:1900005(positive regulation of serine-type endopeptidase activity);GO:1900004(negative regulation of serine-type endopeptidase activity);GO:0001851(complement component C3b binding);GO:0001855(complement component C4b binding);GO:0001861(complement component C4b receptor activity);GO:0004877(complement component C3b receptor activity);GO:0045957(negative regulation of complement activation, alternative pathway);GO:0045959(negative regulation of complement activation, classical pathway)","04640(Hematopoietic cell lineage);04610(Complement and coagulation cascades);05134(Legionellosis);05152(Tuberculosis);05144(Malaria);05140(Leishmaniasis)","K04011","NA","complement C3b/C4b receptor 1 (Knops blood group) [Source:HGNC Symbol;Acc:HGNC:2334]",{"v":6.619052,"d":"6.62"},{"v":0.897355,"d":"0.90"},{"v":7.37617999565389,"d":"7.38"},{"v":2.88287386125381,"d":"2.88"},{"v":1.22303650061264E-4,"d":"0.00"},{"v":0.00479236559883621,"d":"0.00"},"up","yes"]
[183161,0,"chr8","+",38787263,38853028,"ENST00000276520",11,6513,"MSTRG.14302","TACC1","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0051301(cell division);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0007049(cell cycle);GO:0005815(microtubule organizing center);GO:0030496(midbody);GO:0000226(microtubule cytoskeleton organization);GO:0008283(cell proliferation);GO:0021987(cerebral cortex development);GO:0015630(microtubule cytoskeleton)","NA","NA","NA","transforming acidic coiled-coil containing protein 1 [Source:HGNC Symbol;Acc:HGNC:11522]",{"v":0.217957,"d":"0.22"},{"v":1.264644,"d":"1.26"},{"v":0.172346525978853,"d":"0.17"},{"v":-2.53661587656277,"d":"-2.54"},{"v":0.000123389777302577,"d":"0.00"},{"v":0.00482536939380119,"d":"0.00"},"down","yes"]
[194126,0,"chr9","-",129812944,129824134,"ENST00000351698",5,2076,"MSTRG.15033","TOR1A","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0043231(intracellular membrane-bounded organelle);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0016787(hydrolase activity);GO:0031965(nuclear membrane);GO:0007155(cell adhesion);GO:0005783(endoplasmic reticulum);GO:0005856(cytoskeleton);GO:0042995(cell projection);GO:0005515(protein binding);GO:0031175(neuron projection development);GO:0008092(cytoskeletal protein binding);GO:0030054(cell junction);GO:0045202(synapse);GO:0030659(cytoplasmic vesicle membrane);GO:0031410(cytoplasmic vesicle);GO:0051082(unfolded protein binding);GO:0006998(nuclear envelope organization);GO:0045104(intermediate filament cytoskeleton organization);GO:0005635(nuclear envelope);GO:0005788(endoplasmic reticulum lumen);GO:0005829(cytosol);GO:0030426(growth cone);GO:0070062(extracellular exosome);GO:0016887(ATPase activity);GO:0061077(chaperone-mediated protein folding);GO:0019894(kinesin binding);GO:0051787(misfolded protein binding);GO:0000338(protein deneddylation);GO:0006979(response to oxidative stress);GO:0006996(organelle organization);GO:0034504(protein localization to nucleus);GO:0044319(wound healing, spreading of cells);GO:0048489(synaptic vesicle transport);GO:0051085(chaperone mediated protein folding requiring cofactor);GO:0051260(protein homooligomerization);GO:0051584(regulation of dopamine uptake involved in synaptic transmission);GO:0071712(ER-associated misfolded protein catabolic process);GO:0071763(nuclear membrane organization);GO:0072321(chaperone-mediated protein transport);GO:1900244(positive regulation of synaptic vesicle endocytosis);GO:2000008(regulation of protein localization to cell surface);GO:0008021(synaptic vesicle);GO:0030133(transport vesicle);GO:0030141(secretory granule);GO:0042406(extrinsic component of endoplasmic reticulum membrane);GO:0043005(neuron projection)","NA","NA","NA","torsin family 1 member A [Source:HGNC Symbol;Acc:HGNC:3098]",{"v":4.675434,"d":"4.68"},{"v":0.612684,"d":"0.61"},{"v":7.63106919717179,"d":"7.63"},{"v":2.93188520874919,"d":"2.93"},{"v":0.000124784765863941,"d":"0.00"},{"v":0.00485642639929063,"d":"0.00"},"up","yes"]
[196059,"j","chrX","-",20150562,20266721,"MSTRG.15199.2",23,3087,"MSTRG.15199","RPS6KA3","NA","NA","NA","NA","NA",{"v":3.227866,"d":"3.23"},{"v":0.425353,"d":"0.43"},{"v":7.58867575872276,"d":"7.59"},{"v":2.92384815401951,"d":"2.92"},{"v":0.000124815579227499,"d":"0.00"},{"v":0.00485642639929063,"d":"0.00"},"up","yes"]
[133790,0,"chr3","-",15667239,15859422,"ENST00000412318",29,4408,"MSTRG.10693","ANKRD28","GO:0005634(nucleus);GO:0005515(protein binding);GO:0005654(nucleoplasm);GO:0000139(Golgi membrane);GO:0005829(cytosol);GO:0048208(COPII vesicle coating)","NA","NA","NA","ankyrin repeat domain 28 [Source:HGNC Symbol;Acc:HGNC:29024]",{"v":2.500223,"d":"2.50"},{"v":0.327277,"d":"0.33"},{"v":7.63947054024572,"d":"7.64"},{"v":2.93347265456589,"d":"2.93"},{"v":0.000124920206046035,"d":"0.00"},{"v":0.00485642639929063,"d":"0.00"},"up","yes"]
[142658,0,"chr3","-",171063881,171460063,"ENST00000357327",32,3996,"MSTRG.11337","TNIK","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0016055(Wnt signaling pathway);GO:0007399(nervous system development);GO:0000185(activation of MAPKKK activity);GO:0005768(endosome);GO:0070062(extracellular exosome);GO:0001934(positive regulation of protein phosphorylation);GO:0007010(cytoskeleton organization);GO:0055037(recycling endosome);GO:0016324(apical plasma membrane);GO:0042981(regulation of apoptotic process);GO:0046777(protein autophosphorylation);GO:0008349(MAP kinase kinase kinase kinase activity);GO:0007346(regulation of mitotic cell cycle);GO:0035556(intracellular signal transduction);GO:0030033(microvillus assembly);GO:0031532(actin cytoskeleton reorganization);GO:0048814(regulation of dendrite morphogenesis);GO:0072659(protein localization to plasma membrane);GO:0007256(activation of JNKK activity)","NA","NA","NA","TRAF2 and NCK interacting kinase [Source:HGNC Symbol;Acc:HGNC:30765]",{"v":0.217887,"d":"0.22"},{"v":1.309745,"d":"1.31"},{"v":0.166358336928181,"d":"0.17"},{"v":-2.5876339272325,"d":"-2.59"},{"v":0.000126080166789952,"d":"0.00"},{"v":4.89191047145013E-3,"d":"0.00"},"down","yes"]
[36137,0,"chr11","-",119660992,119729084,"ENST00000264025",6,5840,"ENSG00000110400","NECTIN1","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0007155(cell adhesion);GO:0046982(protein heterodimerization activity);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0042803(protein homodimerization activity);GO:0005576(extracellular region);GO:0006955(immune response);GO:0030054(cell junction);GO:0045202(synapse);GO:0007165(signal transduction);GO:0005912(adherens junction);GO:0005887(integral component of plasma membrane);GO:0016032(viral process);GO:0050839(cell adhesion molecule binding);GO:0046718(viral entry into host cell);GO:0005913(cell-cell adherens junction);GO:0042734(presynaptic membrane);GO:0015026(coreceptor activity);GO:0005102(receptor binding);GO:0007156(homophilic cell adhesion via plasma membrane adhesion molecules);GO:0007157(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules);GO:0001618(virus receptor activity);GO:0016337(single organismal cell-cell adhesion);GO:0034332(adherens junction organization);GO:0008037(cell recognition);GO:0051963(regulation of synapse assembly);GO:0004872(receptor activity);GO:0030246(carbohydrate binding);GO:0046790(virion binding);GO:0002089(lens morphogenesis in camera-type eye);GO:0002934(desmosome organization);GO:0006826(iron ion transport);GO:0007411(axon guidance);GO:0048593(camera-type eye morphogenesis);GO:0060041(retina development in camera-type eye);GO:0070166(enamel mineralization);GO:1902414(protein localization to cell junction);GO:0016342(catenin complex);GO:0030424(axon);GO:0032584(growth cone membrane);GO:0043005(neuron projection);GO:0043231(intracellular membrane-bounded organelle);GO:0043296(apical junction complex);GO:0044291(cell-cell contact zone)","04514(Cell adhesion molecules (CAMs));04520(Adherens junction);05168(Herpes simplex infection)","K06081","NA","nectin cell adhesion molecule 1 [Source:HGNC Symbol;Acc:HGNC:9706]",{"v":2.195964,"d":"2.20"},{"v":0.291395,"d":"0.29"},{"v":7.53603871034163,"d":"7.54"},{"v":2.91380637565591,"d":"2.91"},{"v":0.00012709101009183,"d":"0.00"},{"v":0.00490290325913382,"d":"0.00"},"up","yes"]
[183654,0,"chr8","-",47773108,47960183,"ENST00000314191",86,13509,"ENSG00000253729","PRKDC","GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0005634(nucleus);GO:0003723(RNA binding);GO:0016020(membrane);GO:0000166(nucleotide binding);GO:0004674(protein serine/threonine kinase activity);GO:0005524(ATP binding);GO:0005654(nucleoplasm);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0006303(double-strand break repair via nonhomologous end joining);GO:0006281(DNA repair);GO:0006310(DNA recombination);GO:0006974(cellular response to DNA damage stimulus);GO:0048511(rhythmic process);GO:0005730(nucleolus);GO:0016567(protein ubiquitination);GO:0005829(cytosol);GO:0000784(nuclear chromosome, telomeric region);GO:0031012(extracellular matrix);GO:0005667(transcription factor complex);GO:0001933(negative regulation of protein phosphorylation);GO:0043234(protein complex);GO:0019904(protein domain specific binding);GO:0006464(cellular protein modification process);GO:0004672(protein kinase activity);GO:0032481(positive regulation of type I interferon production);GO:0042752(regulation of circadian rhythm);GO:0018105(peptidyl-serine phosphorylation);GO:0032869(cellular response to insulin stimulus);GO:0008134(transcription factor binding);GO:0032993(protein-DNA complex);GO:0043066(negative regulation of apoptotic process);GO:0008283(cell proliferation);GO:0006468(protein phosphorylation);GO:0003690(double-stranded DNA binding);GO:0048660(regulation of smooth muscle cell proliferation);GO:0070419(nonhomologous end joining complex);GO:0006302(double-strand break repair);GO:0005958(DNA-dependent protein kinase-DNA ligase 4 complex);GO:0004677(DNA-dependent protein kinase activity);GO:0019899(enzyme binding);GO:0000723(telomere maintenance);GO:0001756(somitogenesis);GO:0002326(B cell lineage commitment);GO:0002328(pro-B cell differentiation);GO:0002360(T cell lineage commitment);GO:0002377(immunoglobulin production);GO:0002638(negative regulation of immunoglobulin production);GO:0002684(positive regulation of immune system process);GO:0007420(brain development);GO:0007507(heart development);GO:0008630(intrinsic apoptotic signaling pathway in response to DNA damage);GO:0010212(response to ionizing radiation);GO:0010332(response to gamma radiation);GO:0014823(response to activity);GO:0016233(telomere capping);GO:0030098(lymphocyte differentiation);GO:0031648(protein destabilization);GO:0033077(T cell differentiation in thymus);GO:0033151(V(D)J recombination);GO:0033152(immunoglobulin V(D)J recombination);GO:0033153(T cell receptor V(D)J recombination);GO:0035234(ectopic germ cell programmed cell death);GO:0043065(positive regulation of apoptotic process);GO:0048146(positive regulation of fibroblast proliferation);GO:0048536(spleen development);GO:0048538(thymus development);GO:0048639(positive regulation of developmental growth);GO:0072431(signal transduction involved in mitotic G1 DNA damage checkpoint);GO:0097681(double-strand break repair via alternative nonhomologous end joining);GO:2000773(negative regulation of cellular senescence);GO:2001229(negative regulation of response to gamma radiation)","03450(Non-homologous end-joining);04110(Cell cycle)","K06642","EC:2.7.11.1","protein kinase, DNA-activated, catalytic polypeptide [Source:HGNC Symbol;Acc:HGNC:9413]",{"v":4.935185,"d":"4.94"},{"v":0.673762,"d":"0.67"},{"v":7.32481944662952,"d":"7.32"},{"v":2.87279319821576,"d":"2.87"},{"v":0.000127109510254757,"d":"0.00"},{"v":0.00490290325913382,"d":"0.00"},"up","yes"]
[105415,0,"chr19","+",54200858,54206565,"ENST00000626547",5,476,"MSTRG.8410","RPS9","GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0006412(translation);GO:0030529(intracellular ribonucleoprotein complex);GO:0005622(intracellular);GO:0003735(structural constituent of ribosome);GO:0005840(ribosome);GO:0015935(small ribosomal subunit);GO:0005515(protein binding);GO:0022627(cytosolic small ribosomal subunit);GO:0019843(rRNA binding);GO:0005730(nucleolus);GO:0005925(focal adhesion);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0008284(positive regulation of cell proliferation);GO:0006413(translational initiation);GO:0006364(rRNA processing);GO:0000184(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay);GO:0019083(viral transcription);GO:0006614(SRP-dependent cotranslational protein targeting to membrane);GO:0045182(translation regulator activity);GO:0045903(positive regulation of translational fidelity)","03010(Ribosome)","NA","NA","ribosomal protein S9 [Source:HGNC Symbol;Acc:HGNC:10442]",{"v":6.077865,"d":"6.08"},{"v":34.365509,"d":"34.37"},{"v":0.176859449397359,"d":"0.18"},{"v":-2.49932479224934,"d":"-2.50"},{"v":1.27133924257774E-4,"d":"0.00"},{"v":0.00490290325913382,"d":"0.00"},"down","yes"]
[182690,0,"chr8","-",30063130,30083153,"ENST00000520303",5,1803,"MSTRG.14272","SARAF","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0006811(ion transport);GO:0006816(calcium ion transport);GO:0030176(integral component of endoplasmic reticulum membrane);GO:0005515(protein binding);GO:2001256(regulation of store-operated calcium entry)","NA","NA","NA","store-operated calcium entry associated regulatory factor [Source:HGNC Symbol;Acc:HGNC:28789]",{"v":14.377675,"d":"14.38"},{"v":79.286491,"d":"79.29"},{"v":0.181338268583484,"d":"0.18"},{"v":-2.46324467962539,"d":"-2.46"},{"v":0.000127354572225328,"d":"0.00"},{"v":0.00490290325913382,"d":"0.00"},"down","yes"]
[178493,0,"chr7","-",128392278,128409982,"ENST00000354269",16,2580,"MSTRG.13947","IMPDH1","GO:0055114(oxidation-reduction process);GO:0003824(catalytic activity);GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0005829(cytosol);GO:0016491(oxidoreductase activity);GO:0003677(DNA binding);GO:0006164(purine nucleotide biosynthetic process);GO:0005576(extracellular region);GO:0003676(nucleic acid binding);GO:0006177(GMP biosynthetic process);GO:0043312(neutrophil degranulation);GO:0003938(IMP dehydrogenase activity);GO:0034774(secretory granule lumen);GO:1904813(ficolin-1-rich granule lumen);GO:0035578(azurophil granule lumen);GO:0009168(purine ribonucleoside monophosphate biosynthetic process);GO:0006183(GTP biosynthetic process);GO:0046651(lymphocyte proliferation);GO:0000166(nucleotide binding)","00230(Purine metabolism);00983(Drug metabolism - other enzymes)","K00088","EC:1.1.1.205","inosine monophosphate dehydrogenase 1 [Source:HGNC Symbol;Acc:HGNC:6052]",{"v":5.207597,"d":"5.21"},{"v":0.690755,"d":"0.69"},{"v":7.53899284116655,"d":"7.54"},{"v":2.91437180199432,"d":"2.91"},{"v":0.00012834826506716,"d":"0.00"},{"v":0.00493156401776497,"d":"0.00"},"up","yes"]
[61687,0,"chr15","+",43185257,43197176,"ENST00000300213",11,3660,"MSTRG.5021","CCNDBP1","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005654(nucleoplasm);GO:0005515(protein binding);GO:0007049(cell cycle);GO:0051726(regulation of cell cycle)","NA","NA","NA","cyclin D1 binding protein 1 [Source:HGNC Symbol;Acc:HGNC:1587]",{"v":5.031343,"d":"5.03"},{"v":27.675268,"d":"27.68"},{"v":0.181799251230377,"d":"0.18"},{"v":-2.459581837316,"d":"-2.46"},{"v":0.000130074029439344,"d":"0.00"},{"v":0.0049797142485002,"d":"0.00"},"down","yes"]
[166360,0,"chr6","+",44127639,44149261,"ENST00000534326",15,1934,"MSTRG.13078","TMEM63B","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005886(plasma membrane);GO:0006811(ion transport);GO:0015629(actin cytoskeleton)","NA","NA","NA","transmembrane protein 63B [Source:HGNC Symbol;Acc:HGNC:17735]",{"v":5.443092,"d":"5.44"},{"v":0.716946,"d":"0.72"},{"v":7.59205295796336,"d":"7.59"},{"v":2.92449005583698,"d":"2.92"},{"v":1.30313135840136E-4,"d":"0.00"},{"v":0.0049797142485002,"d":"0.00"},"up","yes"]
[51017,0,"chr13","-",77044902,77087514,"ENST00000429715",22,3660,"MSTRG.4036","MYCBP2","GO:0005634(nucleus);GO:0016020(membrane);GO:0046872(metal ion binding);GO:0016740(transferase activity);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0016567(protein ubiquitination);GO:0005515(protein binding);GO:0004842(ubiquitin-protein transferase activity)","NA","NA","NA","MYC binding protein 2, E3 ubiquitin protein ligase [Source:HGNC Symbol;Acc:HGNC:23386]",{"v":0.811792,"d":"0.81"},{"v":4.555025,"d":"4.56"},{"v":0.17821899989572,"d":"0.18"},{"v":-2.48827694436795,"d":"-2.49"},{"v":0.000130356376628416,"d":"0.00"},{"v":0.0049797142485002,"d":"0.00"},"down","yes"]
[108251,0,"chr2","+",27428640,27442255,"ENST00000379852",18,2163,"MSTRG.8575","NRBP1","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0004672(protein kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0042803(protein homodimerization activity);GO:0042995(cell projection);GO:0005515(protein binding);GO:0004674(protein serine/threonine kinase activity);GO:0035556(intracellular signal transduction);GO:0005654(nucleoplasm);GO:0030027(lamellipodium);GO:0005938(cell cortex);GO:0005829(cytosol);GO:0012505(endomembrane system);GO:0006888(ER to Golgi vesicle-mediated transport);GO:0006367(transcription initiation from RNA polymerase II promoter)","NA","NA","NA","nuclear receptor binding protein 1 [Source:HGNC Symbol;Acc:HGNC:7993]",{"v":3.201363,"d":"3.20"},{"v":17.695461,"d":"17.70"},{"v":0.180914359902802,"d":"0.18"},{"v":-2.4666211698561,"d":"-2.47"},{"v":1.31351234973572E-4,"d":"0.00"},{"v":0.0050080505542525,"d":"0.01"},"down","yes"]
[116485,0,"chr2","-",173908530,173964219,"ENST00000418194",5,3937,"MSTRG.9242","SP3","GO:0005634(nucleus);GO:0003676(nucleic acid binding);GO:0046872(metal ion binding);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0005515(protein binding);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0045893(positive regulation of transcription, DNA-templated);GO:0000987(core promoter proximal region sequence-specific DNA binding);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0005654(nucleoplasm);GO:0000981(RNA polymerase II transcription factor activity, sequence-specific DNA binding);GO:0045892(negative regulation of transcription, DNA-templated);GO:0016605(PML body);GO:0000977(RNA polymerase II regulatory region sequence-specific DNA binding);GO:0016925(protein sumoylation);GO:0000979(RNA polymerase II core promoter sequence-specific DNA binding);GO:0001078(transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0003682(chromatin binding);GO:0003690(double-stranded DNA binding);GO:0001503(ossification);GO:0001701(in utero embryonic development);GO:0001779(natural killer cell differentiation);GO:0001829(trophectodermal cell differentiation);GO:0001889(liver development);GO:0001892(embryonic placenta development);GO:0030183(B cell differentiation);GO:0030217(T cell differentiation);GO:0030218(erythrocyte differentiation);GO:0030219(megakaryocyte differentiation);GO:0030224(monocyte differentiation);GO:0030324(lung development);GO:0030851(granulocyte differentiation);GO:0043353(enucleate erythrocyte differentiation);GO:0048596(embryonic camera-type eye morphogenesis);GO:0048706(embryonic skeletal system development);GO:0060136(embryonic process involved in female pregnancy);GO:0060216(definitive hemopoiesis);GO:0017053(transcriptional repressor complex)","NA","NA","NA","Sp3 transcription factor [Source:HGNC Symbol;Acc:HGNC:11208]",{"v":8.668875,"d":"8.67"},{"v":1.187173,"d":"1.19"},{"v":7.30211603532088,"d":"7.30"},{"v":2.86831459430716,"d":"2.87"},{"v":1.33710055468873E-4,"d":"0.00"},{"v":0.00508818188003471,"d":"0.01"},"up","yes"]
[125323,0,"chr20","-",62877738,62937952,"ENST00000266070",16,8574,"MSTRG.9883","DIDO1","GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0006351(transcription, DNA-templated);GO:0005856(cytoskeleton);GO:0006915(apoptotic process);GO:0005819(spindle);GO:0097190(apoptotic signaling pathway)","NA","NA","NA","death inducer-obliterator 1 [Source:HGNC Symbol;Acc:HGNC:2680]",{"v":2.557241,"d":"2.56"},{"v":0.346925,"d":"0.35"},{"v":7.37116379620956,"d":"7.37"},{"v":2.88189241721294,"d":"2.88"},{"v":0.00013537559712755,"d":"0.00"},{"v":0.00514167431086365,"d":"0.01"},"up","yes"]
[75046,0,"chr16","+",69566062,69697840,"ENST00000567239",15,6376,"ENSG00000102908","NFAT5","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0006366(transcription from RNA polymerase II promoter);GO:0005515(protein binding);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0007165(signal transduction);GO:0001077(transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0007588(excretion);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0001816(cytokine production);GO:0006970(response to osmotic stress);GO:0010628(positive regulation of gene expression);GO:0070884(regulation of calcineurin-NFAT signaling cascade)","NA","NA","NA","nuclear factor of activated T-cells 5 [Source:HGNC Symbol;Acc:HGNC:7774]",{"v":1.00216,"d":"1.00"},{"v":0.130288,"d":"0.13"},{"v":7.6918825985509,"d":"7.69"},{"v":2.94333674294549,"d":"2.94"},{"v":1.35933476325983E-4,"d":"0.00"},{"v":0.00515297247038038,"d":"0.01"},"up","yes"]
[179042,0,"chr7","+",135662521,135676412,"ENST00000507606",3,2450,"MSTRG.13995","C7orf73","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005739(mitochondrion);GO:0031966(mitochondrial membrane)","NA","NA","NA","chromosome 7 open reading frame 73 [Source:HGNC Symbol;Acc:HGNC:41909]",{"v":15.163783,"d":"15.16"},{"v":2.081832,"d":"2.08"},{"v":7.28386488439029,"d":"7.28"},{"v":2.86470416058657,"d":"2.86"},{"v":1.36780514144647E-4,"d":"0.00"},{"v":0.00517516790419554,"d":"0.01"},"up","yes"]
[130519,0,"chr22","-",31619103,31662432,"ENST00000439502",8,1963,"MSTRG.10401","PISD","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005743(mitochondrial inner membrane);GO:0016829(lyase activity);GO:0006629(lipid metabolic process);GO:0005739(mitochondrion);GO:0008654(phospholipid biosynthetic process);GO:0004609(phosphatidylserine decarboxylase activity);GO:0016831(carboxy-lyase activity);GO:0006646(phosphatidylethanolamine biosynthetic process);GO:0016540(protein autoprocessing);GO:0031305(integral component of mitochondrial inner membrane);GO:0005634(nucleus)","00564(Glycerophospholipid metabolism)","NA","NA","phosphatidylserine decarboxylase [Source:HGNC Symbol;Acc:HGNC:8999]",{"v":6.820562,"d":"6.82"},{"v":0.916897,"d":"0.92"},{"v":7.43874393743245,"d":"7.44"},{"v":2.89505903689511,"d":"2.90"},{"v":0.000137905657460902,"d":"0.00"},{"v":0.00520778082029835,"d":"0.01"},"up","yes"]
[70589,0,"chr16","-",21447078,21501886,"ENST00000522480",29,4262,"ENSG00000180747","SMG1P3","NA","NA","NA","NA","SMG1P3, nonsense mediated mRNA decay associated PI3K related kinase pseudogene 3 [Source:HGNC Symbol;Acc:HGNC:49860]",{"v":2.001333,"d":"2.00"},{"v":0.26262,"d":"0.26"},{"v":7.62064199223212,"d":"7.62"},{"v":2.92991254102505,"d":"2.93"},{"v":0.000138898984398959,"d":"0.00"},{"v":0.00523530114911734,"d":"0.01"},"up","yes"]
[132534,0,"chr22","-",50446806,50474942,"ENST00000348911",40,6045,"MSTRG.10605","SBF1","GO:0005634(nucleus);GO:0016021(integral component of membrane);GO:0043547(positive regulation of GTPase activity);GO:0019208(phosphatase regulator activity);GO:0007283(spermatogenesis);GO:0043087(regulation of GTPase activity);GO:0005085(guanyl-nucleotide exchange factor activity);GO:0005789(endoplasmic reticulum membrane);GO:0005829(cytosol);GO:0017112(Rab guanyl-nucleotide exchange factor activity);GO:0061024(membrane organization);GO:0006661(phosphatidylinositol biosynthetic process);GO:0006470(protein dephosphorylation);GO:0008138(protein tyrosine/serine/threonine phosphatase activity)","NA","NA","NA","SET binding factor 1 [Source:HGNC Symbol;Acc:HGNC:10542]",{"v":5.835253,"d":"5.84"},{"v":0.804804,"d":"0.80"},{"v":7.25052683634773,"d":"7.25"},{"v":2.85808582775816,"d":"2.86"},{"v":0.000141173137816017,"d":"0.00"},{"v":0.00531090123783907,"d":"0.01"},"up","yes"]
[197071,0,"chrX","+",48898041,48903143,"ENST00000474671",7,917,"MSTRG.15287","PQBP1","GO:0006397(mRNA processing);GO:0008380(RNA splicing);GO:0005634(nucleus);GO:0016607(nuclear speck);GO:0005829(cytosol);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0005515(protein binding);GO:0005654(nucleoplasm);GO:0003677(DNA binding);GO:0003713(transcription coactivator activity);GO:0031175(neuron projection development);GO:0000398(mRNA splicing, via spliceosome);GO:0043021(ribonucleoprotein complex binding);GO:0000380(alternative mRNA splicing, via spliceosome);GO:0043484(regulation of RNA splicing);GO:0034063(stress granule assembly);GO:0048814(regulation of dendrite morphogenesis);GO:0005737(cytoplasm);GO:0010494(cytoplasmic stress granule);GO:0071598(neuronal ribonucleoprotein granule)","03040(Spliceosome)","NA","NA","polyglutamine binding protein 1 [Source:HGNC Symbol;Acc:HGNC:9330]",{"v":2.359903,"d":"2.36"},{"v":13.241248,"d":"13.24"},{"v":0.178223608529951,"d":"0.18"},{"v":-2.48823963763978,"d":"-2.49"},{"v":0.000141840500256598,"d":"0.00"},{"v":0.00532588200963482,"d":"0.01"},"down","yes"]
[166248,0,"chr6","-",43511827,43516990,"ENST00000372422",9,1576,"MSTRG.13067","YIPF3","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005794(Golgi apparatus);GO:0043231(intracellular membrane-bounded organelle);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0030154(cell differentiation);GO:0030133(transport vesicle)","NA","NA","NA","Yip1 domain family member 3 [Source:HGNC Symbol;Acc:HGNC:21023]",{"v":37.285679,"d":"37.29"},{"v":5.172498,"d":"5.17"},{"v":7.20844725314539,"d":"7.21"},{"v":2.84968852695014,"d":"2.85"},{"v":0.000142529806896734,"d":"0.00"},{"v":0.00533770527008518,"d":"0.01"},"up","yes"]
[6925,0,"chr1","+",65420587,65436007,"ENST00000371065",4,4622,"MSTRG.619","LEPROT","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005794(Golgi apparatus);GO:0000139(Golgi membrane);GO:0005768(endosome);GO:0010008(endosome membrane);GO:0005102(receptor binding);GO:1903955(positive regulation of protein targeting to mitochondrion);GO:2000009(negative regulation of protein localization to cell surface);GO:0032511(late endosome to vacuole transport via multivesicular body sorting pathway);GO:0046426(negative regulation of JAK-STAT cascade);GO:0060400(negative regulation of growth hormone receptor signaling pathway)","NA","NA","NA","leptin receptor overlapping transcript [Source:HGNC Symbol;Acc:HGNC:29477]",{"v":1.811065,"d":"1.81"},{"v":9.893847,"d":"9.89"},{"v":0.183049626702333,"d":"0.18"},{"v":-2.44969326336586,"d":"-2.45"},{"v":1.42694870015922E-4,"d":"0.00"},{"v":0.00533770527008518,"d":"0.01"},"down","yes"]
[63149,0,"chr15","-",59663366,59689280,"ENST00000607373",10,1851,"MSTRG.5146","BNIP2","GO:0001824(blastocyst development);GO:0007098(centrosome cycle);GO:0043410(positive regulation of MAPK cascade);GO:0045666(positive regulation of neuron differentiation);GO:0051057(positive regulation of small GTPase mediated signal transduction);GO:0051146(striated muscle cell differentiation);GO:0005814(centriole);GO:0031616(spindle pole centrosome);GO:0005737(cytoplasm);GO:0043547(positive regulation of GTPase activity);GO:0005515(protein binding);GO:0006915(apoptotic process);GO:0048471(perinuclear region of cytoplasm);GO:0005509(calcium ion binding);GO:0005829(cytosol);GO:0043231(intracellular membrane-bounded organelle);GO:0043066(negative regulation of apoptotic process);GO:0005635(nuclear envelope);GO:0005096(GTPase activator activity);GO:0051149(positive regulation of muscle cell differentiation);GO:0042802(identical protein binding);GO:0016020(membrane);GO:0016021(integral component of membrane)","NA","NA","NA","BCL2 interacting protein 2 [Source:HGNC Symbol;Acc:HGNC:1083]",{"v":20.877766,"d":"20.88"},{"v":2.893639,"d":"2.89"},{"v":7.21505550623281,"d":"7.22"},{"v":2.85101049357424,"d":"2.85"},{"v":1.45660058315139E-4,"d":"0.00"},{"v":0.00543580589356665,"d":"0.01"},"up","yes"]
[133626,0,"chr3","+",14402576,14489349,"ENST00000618278",14,6401,"MSTRG.10680","SLC6A6","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005887(integral component of plasma membrane);GO:0015293(symporter activity);GO:0055085(transmembrane transport);GO:0005328(neurotransmitter:sodium symporter activity);GO:0006836(neurotransmitter transport);GO:0098656(anion transmembrane transport);GO:0005368(taurine transmembrane transporter activity);GO:0005369(taurine:sodium symporter activity);GO:0015734(taurine transport);GO:1903825(organic acid transmembrane transport);GO:0015711(organic anion transport);GO:0042918(alkanesulfonate transport);GO:0005886(plasma membrane);GO:0003333(amino acid transmembrane transport);GO:0015171(amino acid transmembrane transporter activity);GO:0006520(cellular amino acid metabolic process);GO:0006865(amino acid transport)","NA","NA","NA","solute carrier family 6 member 6 [Source:HGNC Symbol;Acc:HGNC:11052]",{"v":0.141006,"d":"0.14"},{"v":0.82578,"d":"0.83"},{"v":0.170754922618615,"d":"0.17"},{"v":-2.55000092495123,"d":"-2.55"},{"v":1.45866834924393E-4,"d":"0.00"},{"v":0.00543580589356665,"d":"0.01"},"down","yes"]
[11265,0,"chr1","-",153959099,153963572,"ENST00000356205",4,2084,"MSTRG.997","SLC39A1","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0055085(transmembrane transport);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0006811(ion transport);GO:0005886(plasma membrane);GO:0046873(metal ion transmembrane transporter activity);GO:0030001(metal ion transport);GO:0005385(zinc ion transmembrane transporter activity);GO:0006829(zinc II ion transport);GO:0071577(zinc II ion transmembrane transport);GO:0022890(inorganic cation transmembrane transporter activity);GO:0006812(cation transport);GO:0005102(receptor binding);GO:0001701(in utero embryonic development);GO:0048701(embryonic cranial skeleton morphogenesis);GO:0060173(limb development)","NA","NA","NA","solute carrier family 39 member 1 [Source:HGNC Symbol;Acc:HGNC:12876]",{"v":16.5474,"d":"16.55"},{"v":2.292223,"d":"2.29"},{"v":7.21893114238885,"d":"7.22"},{"v":2.8517852429672,"d":"2.85"},{"v":1.46501006879141E-4,"d":"0.00"},{"v":0.00544917654910611,"d":"0.01"},"up","yes"]
[122530,0,"chr20","-",23633657,23638473,"ENST00000398409",4,832,"MSTRG.9624","CST3","GO:0005615(extracellular space);GO:0010951(negative regulation of endopeptidase activity);GO:0005576(extracellular region);GO:0004869(cysteine-type endopeptidase inhibitor activity);GO:0030414(peptidase inhibitor activity);GO:0010466(negative regulation of peptidase activity);GO:0042802(identical protein binding);GO:0002020(protease binding);GO:0001654(eye development);GO:0001666(response to hypoxia);GO:0001775(cell activation);GO:0006915(apoptotic process);GO:0006979(response to oxidative stress);GO:0007420(brain development);GO:0007431(salivary gland development);GO:0007566(embryo implantation);GO:0008284(positive regulation of cell proliferation);GO:0008584(male gonad development);GO:0009636(response to toxic substance);GO:0009743(response to carbohydrate);GO:0010035(response to inorganic substance);GO:0014070(response to organic cyclic compound);GO:0031667(response to nutrient levels);GO:0032355(response to estradiol);GO:0034599(cellular response to oxidative stress);GO:0042493(response to drug);GO:0042747(circadian sleep/wake cycle, REM sleep);GO:0043067(regulation of programmed cell death);GO:0045740(positive regulation of DNA replication);GO:0048678(response to axon injury);GO:0060009(Sertoli cell development);GO:0060548(negative regulation of cell death);GO:0070301(cellular response to hydrogen peroxide);GO:0005604(basement membrane);GO:0005737(cytoplasm);GO:0005764(lysosome);GO:0005771(multivesicular body);GO:0005783(endoplasmic reticulum);GO:0030424(axon);GO:0031965(nuclear membrane);GO:0031982(vesicle);GO:0042995(cell projection);GO:0043025(neuronal cell body);GO:0043292(contractile fiber);GO:0048471(perinuclear region of cytoplasm);GO:0005515(protein binding);GO:0070062(extracellular exosome);GO:0044267(cellular protein metabolic process);GO:0043687(post-translational protein modification);GO:0043312(neutrophil degranulation);GO:1904813(ficolin-1-rich granule lumen);GO:0005788(endoplasmic reticulum lumen);GO:1904724(tertiary granule lumen);GO:0097435(supramolecular fiber organization);GO:2000117(negative regulation of cysteine-type endopeptidase activity);GO:0001540(amyloid-beta binding);GO:0004866(endopeptidase inhibitor activity);GO:0006952(defense response);GO:0010711(negative regulation of collagen catabolic process);GO:0010716(negative regulation of extracellular matrix disassembly);GO:0034103(regulation of tissue remodeling);GO:0045861(negative regulation of proteolysis);GO:0060311(negative regulation of elastin catabolic process);GO:0060313(negative regulation of blood vessel remodeling)","04970(Salivary secretion)","NA","NA","cystatin C [Source:HGNC Symbol;Acc:HGNC:2475]",{"v":51.763477,"d":"51.76"},{"v":7.196196,"d":"7.20"},{"v":7.19317219820027,"d":"7.19"},{"v":2.84662814136547,"d":"2.85"},{"v":1.47041917497442E-4,"d":"0.00"},{"v":0.00545903464059922,"d":"0.01"},"up","yes"]
[25849,0,"chr11","-",5253389,5254741,"ENST00000444587",3,307,"MSTRG.2153","HBG2","GO:0006810(transport);GO:0046872(metal ion binding);GO:0005506(iron ion binding);GO:0020037(heme binding);GO:0005344(oxygen transporter activity);GO:0019825(oxygen binding);GO:0015671(oxygen transport);GO:0005833(hemoglobin complex);GO:0005515(protein binding);GO:0005829(cytosol);GO:0072562(blood microparticle);GO:0007596(blood coagulation)","NA","NA","NA","hemoglobin subunit gamma 2 [Source:HGNC Symbol;Acc:HGNC:4832]",{"v":3.746464,"d":"3.75"},{"v":21.56361,"d":"21.56"},{"v":0.173740111233694,"d":"0.17"},{"v":-2.52499722859139,"d":"-2.52"},{"v":0.000147539514468648,"d":"0.00"},{"v":0.00546725077210788,"d":"0.01"},"down","yes"]
[40361,0,"chr12","-",39294387,39443059,"ENST00000544797",34,5040,"ENSG00000139116","KIF21A","GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0003777(microtubule motor activity);GO:0008017(microtubule binding);GO:0003774(motor activity);GO:0007018(microtubule-based movement);GO:0005737(cytoplasm);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0005874(microtubule);GO:0016887(ATPase activity);GO:0005871(kinesin complex)","NA","NA","NA","kinesin family member 21A [Source:HGNC Symbol;Acc:HGNC:19349]",{"v":1.541648,"d":"1.54"},{"v":0.205604,"d":"0.21"},{"v":7.498142059493,"d":"7.50"},{"v":2.90653315912621,"d":"2.91"},{"v":1.48334844669426E-4,"d":"0.00"},{"v":0.00548644842302544,"d":"0.01"},"up","yes"]
[30170,0,"chr11","-",62515905,62546835,"ENST00000378024",5,18787,"MSTRG.2457","AHNAK","GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005765(lysosomal membrane);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0045121(membrane raft);GO:0005925(focal adhesion);GO:0045296(cadherin binding);GO:0070062(extracellular exosome);GO:0042383(sarcolemma);GO:0043484(regulation of RNA splicing);GO:0030315(T-tubule);GO:0031982(vesicle);GO:1901385(regulation of voltage-gated calcium channel activity);GO:0051259(protein oligomerization);GO:0044548(S100 protein binding);GO:0015629(actin cytoskeleton);GO:0043034(costamere);GO:0044291(cell-cell contact zone);GO:0097493(structural molecule activity conferring elasticity)","NA","NA","NA","AHNAK nucleoprotein [Source:HGNC Symbol;Acc:HGNC:347]",{"v":76.84198,"d":"76.84"},{"v":10.822113,"d":"10.82"},{"v":7.10045995638745,"d":"7.10"},{"v":2.82791248311112,"d":"2.83"},{"v":1.5130112561831E-4,"d":"0.00"},{"v":0.00557907906439997,"d":"0.01"},"up","yes"]
[5283,0,"chr1","+",44214833,44220681,"ENST00000488433",7,4552,"ENSG00000178028","DMAP1","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0016569(covalent chromatin modification);GO:0006281(DNA repair);GO:0045892(negative regulation of transcription, DNA-templated);GO:0006338(chromatin remodeling);GO:0005515(protein binding);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0040008(regulation of growth);GO:0003714(transcription corepressor activity);GO:0035267(NuA4 histone acetyltransferase complex);GO:0043967(histone H4 acetylation);GO:0042993(positive regulation of transcription factor import into nucleus);GO:0043968(histone H2A acetylation);GO:0006306(DNA methylation);GO:0001103(RNA polymerase II repressing transcription factor binding);GO:0045471(response to ethanol);GO:0005657(replication fork)","NA","NA","NA","DNA methyltransferase 1 associated protein 1 [Source:HGNC Symbol;Acc:HGNC:18291]",{"v":0.26996,"d":"0.27"},{"v":1.530418,"d":"1.53"},{"v":0.176396252527087,"d":"0.18"},{"v":-2.50310818318703,"d":"-2.50"},{"v":1.51403146229168E-4,"d":"0.00"},{"v":0.00557907906439997,"d":"0.01"},"down","yes"]
[94526,"j","chr19","-",2037604,2050915,"MSTRG.7627.8",11,3883,"MSTRG.7627","MKNK2","NA","NA","NA","NA","NA",{"v":8.351997,"d":"8.35"},{"v":1.159031,"d":"1.16"},{"v":7.20601692275703,"d":"7.21"},{"v":2.84920203982312,"d":"2.85"},{"v":0.000152443146131182,"d":"0.00"},{"v":0.00560696092127105,"d":"0.01"},"up","yes"]
[171421,0,"chr7","-",2728112,2844324,"ENST00000275364",4,4378,"MSTRG.13459","GNA12","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005525(GTP binding);GO:0007264(small GTPase mediated signal transduction);GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0007186(G-protein coupled receptor signaling pathway);GO:0007165(signal transduction);GO:0003924(GTPase activity);GO:0004871(signal transducer activity);GO:0005886(plasma membrane);GO:0001664(G-protein coupled receptor binding);GO:0019001(guanyl nucleotide binding);GO:0031683(G-protein beta/gamma-subunit complex binding);GO:0005925(focal adhesion);GO:0005515(protein binding);GO:0007266(Rho protein signal transduction);GO:0007188(adenylate cyclase-modulating G-protein coupled receptor signaling pathway);GO:0005834(heterotrimeric G-protein complex);GO:0016328(lateral plasma membrane);GO:0007596(blood coagulation);GO:0030168(platelet activation);GO:0032006(regulation of TOR signaling);GO:0032434(regulation of proteasomal ubiquitin-dependent protein catabolic process);GO:0031526(brush border membrane);GO:0031752(D5 dopamine receptor binding);GO:0001701(in utero embryonic development);GO:0008360(regulation of cell shape);GO:0010762(regulation of fibroblast migration);GO:0030154(cell differentiation);GO:0035556(intracellular signal transduction);GO:0042493(response to drug);GO:0042733(embryonic digit morphogenesis)","04010(MAPK signaling pathway);04072(Phospholipase D signaling pathway);04071(Sphingolipid signaling pathway);04022(cGMP - PKG signaling pathway);04810(Regulation of actin cytoskeleton);04270(Vascular smooth muscle contraction);04730(Long-term depression);05200(Pathways in cancer)","K04346","NA","G protein subunit alpha 12 [Source:HGNC Symbol;Acc:HGNC:4380]",{"v":1.168798,"d":"1.17"},{"v":6.360184,"d":"6.36"},{"v":0.183767953883095,"d":"0.18"},{"v":-2.44404288867838,"d":"-2.44"},{"v":1.53004887141498E-4,"d":"0.00"},{"v":0.00561718127412979,"d":"0.01"},"down","yes"]
[13799,"j","chr1","+",174799773,174958462,"MSTRG.1211.15",4,1522,"MSTRG.1211","RABGAP1L","NA","NA","NA","NA","NA",{"v":1.422725,"d":"1.42"},{"v":7.88394,"d":"7.88"},{"v":0.180458628553743,"d":"0.18"},{"v":-2.47025996814385,"d":"-2.47"},{"v":1.53956435323331E-4,"d":"0.00"},{"v":0.00563087192418465,"d":"0.01"},"down","yes"]
[58370,"j","chr14","+",99481407,99510311,"MSTRG.4660.2",11,1532,"MSTRG.4660","CCNK","NA","NA","NA","NA","NA",{"v":13.402427,"d":"13.40"},{"v":1.849194,"d":"1.85"},{"v":7.24771278730084,"d":"7.25"},{"v":2.85752578533078,"d":"2.86"},{"v":0.000153982852429945,"d":"0.00"},{"v":0.00563087192418465,"d":"0.01"},"up","yes"]
[193341,0,"chr9","+",125261843,125363105,"ENST00000394083",25,4747,"ENSG00000165219","GAPVD1","GO:0007165(signal transduction);GO:0043087(regulation of GTPase activity);GO:0016020(membrane);GO:0005829(cytosol);GO:0043547(positive regulation of GTPase activity);GO:0005096(GTPase activator activity);GO:0005085(guanyl-nucleotide exchange factor activity);GO:0032794(GTPase activating protein binding);GO:0051223(regulation of protein transport);GO:0005768(endosome);GO:0045296(cadherin binding);GO:0006897(endocytosis);GO:0017112(Rab guanyl-nucleotide exchange factor activity);GO:0061024(membrane organization)","NA","NA","NA","GTPase activating protein and VPS9 domains 1 [Source:HGNC Symbol;Acc:HGNC:23375]",{"v":3.481621,"d":"3.48"},{"v":0.478297,"d":"0.48"},{"v":7.27920308929389,"d":"7.28"},{"v":2.8637805160758,"d":"2.86"},{"v":1.5423148286376E-4,"d":"0.00"},{"v":0.00563087192418465,"d":"0.01"},"up","yes"]
[71749,0,"chr16","+",30075990,30085377,"ENST00000279387",9,1407,"MSTRG.5820","PPP4C","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0005829(cytosol);GO:0016787(hydrolase activity);GO:0005886(plasma membrane);GO:0004721(phosphoprotein phosphatase activity);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0004722(protein serine/threonine phosphatase activity);GO:0006470(protein dephosphorylation);GO:0030289(protein phosphatase 4 complex);GO:0005815(microtubule organizing center);GO:0005654(nucleoplasm);GO:0010569(regulation of double-strand break repair via homologous recombination);GO:0004704(NF-kappaB-inducing kinase activity);GO:0038061(NIK/NF-kappaB signaling)","04922(Glucagon signaling pathway)","K15423","EC:3.1.3.16","protein phosphatase 4 catalytic subunit [Source:HGNC Symbol;Acc:HGNC:9319]",{"v":6.729336,"d":"6.73"},{"v":36.317184,"d":"36.32"},{"v":0.185293441253595,"d":"0.19"},{"v":-2.4321162790288,"d":"-2.43"},{"v":0.000154687168898397,"d":"0.00"},{"v":0.00563710809974492,"d":"0.01"},"down","yes"]
[85708,0,"chr17","-",50965644,51120865,"ENST00000357122",29,4761,"MSTRG.7030","SPAG9","GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005515(protein binding);GO:0048471(perinuclear region of cytoplasm);GO:0005815(microtubule organizing center);GO:0031410(cytoplasmic vesicle);GO:0070062(extracellular exosome);GO:0030335(positive regulation of cell migration);GO:0001669(acrosomal vesicle);GO:0016021(integral component of membrane);GO:0007283(spermatogenesis);GO:0007257(activation of JUN kinase activity);GO:0005078(MAP-kinase scaffold activity);GO:0008432(JUN kinase binding);GO:0019894(kinesin binding);GO:0030159(receptor signaling complex scaffold activity);GO:0048273(mitogen-activated protein kinase p38 binding);GO:0000187(activation of MAPK activity);GO:0042147(retrograde transport, endosome to Golgi);GO:0043410(positive regulation of MAPK cascade);GO:0045666(positive regulation of neuron differentiation);GO:0051146(striated muscle cell differentiation);GO:0051149(positive regulation of muscle cell differentiation);GO:0051260(protein homooligomerization);GO:0090074(negative regulation of protein homodimerization activity);GO:0016020(membrane)","NA","NA","NA","sperm associated antigen 9 [Source:HGNC Symbol;Acc:HGNC:14524]",{"v":10.769804,"d":"10.77"},{"v":1.508431,"d":"1.51"},{"v":7.13973923898408,"d":"7.14"},{"v":2.83587138440924,"d":"2.84"},{"v":0.000155327195704532,"d":"0.00"},{"v":0.00564854748946956,"d":"0.01"},"up","yes"]
[159489,0,"chr5","-",141653401,141682203,"ENST00000508305",32,4927,"MSTRG.12405","ARAP3","GO:0007165(signal transduction);GO:0043547(positive regulation of GTPase activity);GO:0005096(GTPase activator activity);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0046872(metal ion binding);GO:0005886(plasma membrane);GO:0005856(cytoskeleton);GO:0042995(cell projection);GO:0005515(protein binding);GO:0016192(vesicle-mediated transport);GO:0005829(cytosol);GO:0030027(lamellipodium);GO:0051056(regulation of small GTPase mediated signal transduction);GO:0007010(cytoskeleton organization);GO:0005547(phosphatidylinositol-3,4,5-trisphosphate binding);GO:0043325(phosphatidylinositol-3,4-bisphosphate binding);GO:0008360(regulation of cell shape);GO:0001726(ruffle);GO:0030336(negative regulation of cell migration);GO:0035024(negative regulation of Rho protein signal transduction);GO:0035021(negative regulation of Rac protein signal transduction)","04015(Rap1 signaling pathway);04024(cAMP signaling pathway);04144(Endocytosis)","K12490","NA","ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3 [Source:HGNC Symbol;Acc:HGNC:24097]",{"v":1.739883,"d":"1.74"},{"v":0.233195,"d":"0.23"},{"v":7.46106477411608,"d":"7.46"},{"v":2.89938153325794,"d":"2.90"},{"v":0.000155571982098287,"d":"0.00"},{"v":0.00564854748946956,"d":"0.01"},"up","yes"]
[192671,"j","chr9","-",112218604,112333620,"MSTRG.14903.5",13,6845,"MSTRG.14903","PTBP3","NA","NA","NA","NA","NA",{"v":1.984966,"d":"1.98"},{"v":0.271451,"d":"0.27"},{"v":7.31242839407481,"d":"7.31"},{"v":2.87035059226457,"d":"2.87"},{"v":0.000157103715697353,"d":"0.00"},{"v":0.00569371488318539,"d":"0.01"},"up","yes"]
[134109,0,"chr3","+",23916545,23920977,"ENST00000307839",4,2730,"MSTRG.10731","RPL15","GO:0005634(nucleus);GO:0003723(RNA binding);GO:0016020(membrane);GO:0006412(translation);GO:0030529(intracellular ribonucleoprotein complex);GO:0005622(intracellular);GO:0003735(structural constituent of ribosome);GO:0005840(ribosome);GO:0005515(protein binding);GO:0045471(response to ethanol);GO:0022625(cytosolic large ribosomal subunit);GO:0031672(A band);GO:0005829(cytosol);GO:0045296(cadherin binding);GO:0070062(extracellular exosome);GO:0002181(cytoplasmic translation);GO:0006413(translational initiation);GO:0006364(rRNA processing);GO:0000184(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay);GO:0019083(viral transcription);GO:0006614(SRP-dependent cotranslational protein targeting to membrane)","03010(Ribosome)","K02877","NA","ribosomal protein L15 [Source:HGNC Symbol;Acc:HGNC:10306]",{"v":45.948177,"d":"45.95"},{"v":245.785034,"d":"245.79"},{"v":0.186944567991882,"d":"0.19"},{"v":-2.41931754316188,"d":"-2.42"},{"v":1.57879758505449E-4,"d":"0.00"},{"v":0.00570890412357153,"d":"0.01"},"down","yes"]
[191340,0,"chr9","-",83659971,83686053,"ENST00000533705",9,6055,"MSTRG.14814","UBQLN1","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0005783(endoplasmic reticulum);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0000502(proteasome complex);GO:0048471(perinuclear region of cytoplasm);GO:0006914(autophagy);GO:0031410(cytoplasmic vesicle);GO:0042802(identical protein binding);GO:0000045(autophagosome assembly);GO:0005776(autophagosome);GO:0031398(positive regulation of protein ubiquitination);GO:0030433(ubiquitin-dependent ERAD pathway);GO:0016236(macroautophagy);GO:0071456(cellular response to hypoxia);GO:0034976(response to endoplasmic reticulum stress);GO:0016235(aggresome);GO:0019900(kinase binding);GO:1902175(regulation of oxidative stress-induced intrinsic apoptotic signaling pathway);GO:0043234(protein complex);GO:0031593(polyubiquitin binding);GO:1903071(positive regulation of ER-associated ubiquitin-dependent protein catabolic process);GO:0097352(autophagosome maturation);GO:0035973(aggrephagy);GO:0031396(regulation of protein ubiquitination);GO:0034140(negative regulation of toll-like receptor 3 signaling pathway);GO:1901340(negative regulation of store-operated calcium channel activity)","04141(Protein processing in endoplasmic reticulum)","NA","NA","ubiquilin 1 [Source:HGNC Symbol;Acc:HGNC:12508]",{"v":0.163028,"d":"0.16"},{"v":0.924019,"d":"0.92"},{"v":0.176433601473563,"d":"0.18"},{"v":-2.50280274905524,"d":"-2.50"},{"v":1.58099831196543E-4,"d":"0.00"},{"v":0.00570890412357153,"d":"0.01"},"down","yes"]
[118704,0,"chr2","-",212999691,213151609,"ENST00000451136",8,9344,"ENSG00000030419","IKZF2","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0003674(molecular_function);GO:0008150(biological_process);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0044212(transcription regulatory region DNA binding);GO:0042803(protein homodimerization activity);GO:0046982(protein heterodimerization activity)","NA","NA","NA","IKAROS family zinc finger 2 [Source:HGNC Symbol;Acc:HGNC:13177]",{"v":1.478984,"d":"1.48"},{"v":0.202306,"d":"0.20"},{"v":7.31062845392623,"d":"7.31"},{"v":2.86999543194941,"d":"2.87"},{"v":0.000158806276950397,"d":"0.00"},{"v":0.00571441474013485,"d":"0.01"},"up","yes"]
[86713,0,"chr17","-",63698478,63699162,"ENST00000582055",3,509,"MSTRG.7133","LIMD2","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0005515(protein binding)","NA","NA","NA","LIM domain containing 2 [Source:HGNC Symbol;Acc:HGNC:28142]",{"v":2.176083,"d":"2.18"},{"v":12.303988,"d":"12.30"},{"v":0.176859974180729,"d":"0.18"},{"v":-2.49932051144193,"d":"-2.50"},{"v":0.000158830003389639,"d":"0.00"},{"v":0.00571441474013485,"d":"0.01"},"down","yes"]
[51880,0,"chr13","+",112690329,112887168,"ENST00000375645",30,8795,"ENSG00000068650","ATP11A","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0043231(intracellular membrane-bounded organelle);GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0000287(magnesium ion binding);GO:0016787(hydrolase activity);GO:0005765(lysosomal membrane);GO:0005783(endoplasmic reticulum);GO:0005886(plasma membrane);GO:0006869(lipid transport);GO:0004012(phospholipid-translocating ATPase activity);GO:0015914(phospholipid transport);GO:0005515(protein binding);GO:0005768(endosome);GO:0005769(early endosome);GO:0055037(recycling endosome);GO:0043312(neutrophil degranulation);GO:0035579(specific granule membrane);GO:0070821(tertiary granule membrane);GO:0045332(phospholipid translocation)","NA","NA","NA","ATPase phospholipid transporting 11A [Source:HGNC Symbol;Acc:HGNC:13552]",{"v":2.542304,"d":"2.54"},{"v":0.354688,"d":"0.35"},{"v":7.16771923493324,"d":"7.17"},{"v":2.84151412702964,"d":"2.84"},{"v":0.000161080438800288,"d":"0.00"},{"v":0.00577772694218582,"d":"0.01"},"up","yes"]
[133625,0,"chr3","+",14402576,14489349,"ENST00000613060",15,6526,"MSTRG.10680","SLC6A6","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005887(integral component of plasma membrane);GO:0015293(symporter activity);GO:0055085(transmembrane transport);GO:0005328(neurotransmitter:sodium symporter activity);GO:0006836(neurotransmitter transport);GO:0098656(anion transmembrane transport);GO:0005368(taurine transmembrane transporter activity);GO:0005369(taurine:sodium symporter activity);GO:0015734(taurine transport);GO:1903825(organic acid transmembrane transport);GO:0015711(organic anion transport);GO:0042918(alkanesulfonate transport);GO:0005886(plasma membrane);GO:0003333(amino acid transmembrane transport);GO:0015171(amino acid transmembrane transporter activity);GO:0006520(cellular amino acid metabolic process);GO:0006865(amino acid transport)","NA","NA","NA","solute carrier family 6 member 6 [Source:HGNC Symbol;Acc:HGNC:11052]",{"v":0.136963,"d":"0.14"},{"v":0.788072,"d":"0.79"},{"v":0.173795033956288,"d":"0.17"},{"v":-2.52454123591683,"d":"-2.52"},{"v":1.61173704876014E-4,"d":"0.00"},{"v":0.00577772694218582,"d":"0.01"},"down","yes"]
[13748,0,"chr1","-",173864034,173867729,"ENST00000451607",12,1007,"MSTRG.1204","GAS5","NA","NA","NA","NA","growth arrest specific 5 (non-protein coding) [Source:HGNC Symbol;Acc:HGNC:16355]",{"v":2.018807,"d":"2.02"},{"v":11.181599,"d":"11.18"},{"v":0.180547254466915,"d":"0.18"},{"v":-2.46955161310584,"d":"-2.47"},{"v":0.00016212416196022,"d":"0.00"},{"v":0.00578554883134965,"d":"0.01"},"down","yes"]
[31034,0,"chr11","+",65096227,65108399,"ENST00000529180",4,1027,"MSTRG.2537","VPS51","GO:0017119(Golgi transport complex);GO:0006810(transport);GO:0016021(integral component of membrane);GO:0015031(protein transport);GO:0005794(Golgi apparatus);GO:0005829(cytosol);GO:0043231(intracellular membrane-bounded organelle);GO:0005730(nucleolus);GO:0006869(lipid transport);GO:0006914(autophagy);GO:0005515(protein binding);GO:0005768(endosome);GO:0003674(molecular_function);GO:0042147(retrograde transport, endosome to Golgi);GO:0055037(recycling endosome);GO:0007030(Golgi organization);GO:0032588(trans-Golgi network membrane);GO:0048193(Golgi vesicle transport);GO:0016020(membrane);GO:0032456(endocytic recycling);GO:0007041(lysosomal transport);GO:0000938(GARP complex);GO:1990745(EARP complex);GO:0005802(trans-Golgi network)","NA","NA","NA","VPS51, GARP complex subunit [Source:HGNC Symbol;Acc:HGNC:1172]",{"v":1.11789,"d":"1.12"},{"v":6.372272,"d":"6.37"},{"v":0.175430364554432,"d":"0.18"},{"v":-2.51102961505964,"d":"-2.51"},{"v":0.000162269031807108,"d":"0.00"},{"v":0.00578554883134965,"d":"0.01"},"down","yes"]
[136443,0,"chr3","-",49724295,49786540,"ENST00000395238",5,4117,"MSTRG.10934","IP6K1","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0005829(cytosol);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0001650(fibrillar center);GO:0008440(inositol-1,4,5-trisphosphate 3-kinase activity);GO:0005515(protein binding);GO:0005654(nucleoplasm);GO:0043647(inositol phosphate metabolic process);GO:0000828(inositol hexakisphosphate kinase activity);GO:0000829(inositol heptakisphosphate kinase activity);GO:0000832(inositol hexakisphosphate 5-kinase activity);GO:0052723(inositol hexakisphosphate 1-kinase activity);GO:0052724(inositol hexakisphosphate 3-kinase activity);GO:0046854(phosphatidylinositol phosphorylation);GO:0000827(inositol-1,3,4,5,6-pentakisphosphate kinase activity);GO:0052836(inositol 5-diphosphate pentakisphosphate 5-kinase activity);GO:0052839(inositol diphosphate tetrakisphosphate kinase activity)","04070(Phosphatidylinositol signaling system)","K07756","EC:2.7.4.21","inositol hexakisphosphate kinase 1 [Source:HGNC Symbol;Acc:HGNC:18360]",{"v":0.28027,"d":"0.28"},{"v":1.588846,"d":"1.59"},{"v":0.176398467818782,"d":"0.18"},{"v":-2.50309006505681,"d":"-2.50"},{"v":0.000162269031807108,"d":"0.00"},{"v":0.00578554883134965,"d":"0.01"},"down","yes"]
[24353,"j","chr10","+",128047561,128085855,"MSTRG.2045.7",19,3456,"MSTRG.2045","PTPRE","NA","NA","NA","NA","NA",{"v":1.999234,"d":"2.00"},{"v":0.264328,"d":"0.26"},{"v":7.56345903574347,"d":"7.56"},{"v":2.91904618053257,"d":"2.92"},{"v":1.62567675458689E-4,"d":"0.00"},{"v":0.00578577187405851,"d":"0.01"},"up","yes"]
[186461,0,"chr8","-",108233394,108248698,"ENST00000521440",6,746,"MSTRG.14515","EIF3E","GO:0005737(cytoplasm);GO:0003743(translation initiation factor activity);GO:0005852(eukaryotic translation initiation factor 3 complex);GO:0005829(cytosol);GO:0016604(nuclear body);GO:0006413(translational initiation);GO:0006412(translation);GO:0005634(nucleus);GO:0001731(formation of translation preinitiation complex);GO:0006446(regulation of translational initiation);GO:0016282(eukaryotic 43S preinitiation complex);GO:0033290(eukaryotic 48S preinitiation complex);GO:0003723(RNA binding);GO:0016020(membrane);GO:0005515(protein binding);GO:0005654(nucleoplasm);GO:0045296(cadherin binding);GO:0070062(extracellular exosome);GO:0047485(protein N-terminus binding);GO:0000785(chromatin);GO:0016605(PML body);GO:0000184(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay);GO:0045727(positive regulation of translation);GO:1902416(positive regulation of mRNA binding);GO:0045947(negative regulation of translational initiation)","03013(RNA transport);05160(Hepatitis C)","NA","NA","eukaryotic translation initiation factor 3 subunit E [Source:HGNC Symbol;Acc:HGNC:3277]",{"v":3.741644,"d":"3.74"},{"v":20.40234,"d":"20.40"},{"v":0.183392885325899,"d":"0.18"},{"v":-2.44699042380685,"d":"-2.45"},{"v":1.63685873763846E-4,"d":"0.00"},{"v":0.00581510964100355,"d":"0.01"},"down","yes"]
[165097,0,"chr6","-",32948613,32953108,"ENST00000395303",5,1007,"MSTRG.12935","HLA-DMA","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0043231(intracellular membrane-bounded organelle);GO:0006955(immune response);GO:0002376(immune system process);GO:0002504(antigen processing and presentation of peptide or polysaccharide antigen via MHC class II);GO:0019882(antigen processing and presentation);GO:0042613(MHC class II protein complex);GO:0005765(lysosomal membrane);GO:0005764(lysosome);GO:0005768(endosome);GO:0031902(late endosome membrane);GO:0070062(extracellular exosome);GO:0019886(antigen processing and presentation of exogenous peptide antigen via MHC class II);GO:0009986(cell surface);GO:0023026(MHC class II protein complex binding);GO:0002503(peptide antigen assembly with MHC class II protein complex)","04514(Cell adhesion molecules (CAMs));04145(Phagosome);04640(Hematopoietic cell lineage);04612(Antigen processing and presentation);04658(Th1 and Th2 cell differentiation);04659(Th17 cell differentiation);04672(Intestinal immune network for IgA production);05310(Asthma);05322(Systemic lupus erythematosus);05323(Rheumatoid arthritis);05320(Autoimmune thyroid disease);05321(Inflammatiory bowel disease (IBD));05330(Allograft rejection);05332(Graft-versus-host disease);05416(Viral myocarditis);04940(Type I diabetes mellitus);05150(Staphylococcus aureus infection);05152(Tuberculosis);05166(HTLV-I infection);05164(Influenza A);05168(Herpes simplex infection);05145(Toxoplasmosis);05140(Leishmaniasis)","NA","NA","major histocompatibility complex, class II, DM alpha [Source:HGNC Symbol;Acc:HGNC:4934]",{"v":1.680187,"d":"1.68"},{"v":9.335331,"d":"9.34"},{"v":0.179981513242541,"d":"0.18"},{"v":-2.47407936679353,"d":"-2.47"},{"v":0.000165109101898248,"d":"0.00"},{"v":0.00585515933398302,"d":"0.01"},"down","yes"]
[173740,0,"chr7","+",44796680,44800011,"ENST00000451562",4,544,"MSTRG.13633","PPIA","GO:0016853(isomerase activity);GO:0003755(peptidyl-prolyl cis-trans isomerase activity);GO:0000413(protein peptidyl-prolyl isomerization);GO:0006457(protein folding);GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005829(cytosol);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0005615(extracellular space);GO:0005925(focal adhesion);GO:0050900(leukocyte migration);GO:0070062(extracellular exosome);GO:0019058(viral life cycle);GO:0016032(viral process);GO:0043312(neutrophil degranulation);GO:0035722(interleukin-12-mediated signaling pathway);GO:0034774(secretory granule lumen);GO:1904813(ficolin-1-rich granule lumen);GO:0031982(vesicle);GO:0050714(positive regulation of protein secretion);GO:0051082(unfolded protein binding);GO:0045070(positive regulation of viral genome replication);GO:0019076(viral release from host cell);GO:0075713(establishment of integrated proviral latency);GO:0019064(fusion of virus membrane with host plasma membrane);GO:0030260(entry into host cell);GO:0019068(virion assembly);GO:0046790(virion binding);GO:0016018(cyclosporin A binding);GO:0006278(RNA-dependent DNA biosynthetic process);GO:0019061(uncoating of virus);GO:0034389(lipid particle organization);GO:0045069(regulation of viral genome replication)","04217(Necroptosis)","NA","NA","peptidylprolyl isomerase A [Source:HGNC Symbol;Acc:HGNC:9253]",{"v":13.917689,"d":"13.92"},{"v":1.87958,"d":"1.88"},{"v":7.40468030091829,"d":"7.40"},{"v":2.8884374481088,"d":"2.89"},{"v":1.66999437266169E-4,"d":"0.00"},{"v":0.00590543440719193,"d":"0.01"},"up","yes"]
[8854,"j","chr1","+",109621101,109632055,"MSTRG.768.13",17,3718,"MSTRG.768","AMPD2","NA","NA","NA","NA","NA",{"v":1.805599,"d":"1.81"},{"v":9.671374,"d":"9.67"},{"v":0.186695189328838,"d":"0.19"},{"v":-2.42124334151096,"d":"-2.42"},{"v":0.000167123674349478,"d":"0.00"},{"v":0.00590543440719193,"d":"0.01"},"down","yes"]
[61586,0,"chr15","+",42495260,42533061,"ENST00000249647",8,2687,"MSTRG.5013","SNAP23","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0006810(transport);GO:0005737(cytoplasm);GO:0015031(protein transport);GO:0005654(nucleoplasm);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0030054(cell junction);GO:0045202(synapse);GO:0098793(presynapse);GO:0005925(focal adhesion);GO:0042629(mast cell granule);GO:0070062(extracellular exosome);GO:0002479(antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent);GO:0043312(neutrophil degranulation);GO:0035579(specific granule membrane);GO:0070821(tertiary granule membrane);GO:0005484(SNAP receptor activity);GO:0005913(cell-cell adherens junction);GO:0019905(syntaxin binding);GO:0002553(histamine secretion by mast cell);GO:0006892(post-Golgi vesicle-mediated transport);GO:0006903(vesicle targeting);GO:0016082(synaptic vesicle priming);GO:0031629(synaptic vesicle fusion to presynaptic active zone membrane);GO:0061025(membrane fusion);GO:0030670(phagocytic vesicle membrane);GO:0031201(SNARE complex);GO:0042581(specific granule);GO:0042582(azurophil granule);GO:0043005(neuron projection)","04130(SNARE interactions in vesicular transport);04611(Platelet activation)","K08508","NA","synaptosome associated protein 23 [Source:HGNC Symbol;Acc:HGNC:11131]",{"v":22.034306,"d":"22.03"},{"v":3.12342,"d":"3.12"},{"v":7.05454469779921,"d":"7.05"},{"v":2.81855297390351,"d":"2.82"},{"v":0.000168783187235189,"d":"0.00"},{"v":0.00595344333156849,"d":"0.01"},"up","yes"]
[67290,0,"chr16","+",172890,173710,"ENST00000397806",3,513,"MSTRG.5480","HBA2","GO:0010942(positive regulation of cell death);GO:0006810(transport);GO:0016020(membrane);GO:0046872(metal ion binding);GO:0005506(iron ion binding);GO:0005515(protein binding);GO:0022627(cytosolic small ribosomal subunit);GO:0005615(extracellular space);GO:0020037(heme binding);GO:0098869(cellular oxidant detoxification);GO:0006898(receptor-mediated endocytosis);GO:0005576(extracellular region);GO:0005344(oxygen transporter activity);GO:0019825(oxygen binding);GO:0015671(oxygen transport);GO:0005833(hemoglobin complex);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0072562(blood microparticle);GO:0015701(bicarbonate transport);GO:0042542(response to hydrogen peroxide);GO:0031838(haptoglobin-hemoglobin complex);GO:0071682(endocytic vesicle lumen);GO:0004601(peroxidase activity);GO:0042744(hydrogen peroxide catabolic process);GO:0031720(haptoglobin binding);GO:0051291(protein heterooligomerization)","05144(Malaria);05143(African trypanosomiasis)","NA","NA","hemoglobin subunit alpha 2 [Source:HGNC Symbol;Acc:HGNC:4824]",{"v":645.475037,"d":"645.48"},{"v":3417.821045,"d":"3417.82"},{"v":0.188855714942793,"d":"0.19"},{"v":-2.40464365320683,"d":"-2.40"},{"v":0.000170034375136481,"d":"0.00"},{"v":0.00597444450962564,"d":"0.01"},"down","yes"]
[108365,0,"chr2","+",28392802,28417312,"ENST00000379619",4,5829,"MSTRG.8590","FOSL2","GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0006355(regulation of transcription, DNA-templated);GO:0006366(transcription from RNA polymerase II promoter);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0005515(protein binding);GO:0001228(transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0000977(RNA polymerase II regulatory region sequence-specific DNA binding);GO:0008219(cell death);GO:0003682(chromatin binding);GO:0003334(keratinocyte development);GO:0045893(positive regulation of transcription, DNA-templated);GO:0048146(positive regulation of fibroblast proliferation)","04380(Osteoclast differentiation)","K09030","NA","FOS like 2, AP-1 transcription factor subunit [Source:HGNC Symbol;Acc:HGNC:3798]",{"v":1.049,"d":"1.05"},{"v":0.139883,"d":"0.14"},{"v":7.49912426813837,"d":"7.50"},{"v":2.90672213057112,"d":"2.91"},{"v":0.000170563453137853,"d":"0.00"},{"v":0.00597444450962564,"d":"0.01"},"up","yes"]
[64824,0,"chr15","+",75023555,75050726,"ENST00000342932",6,2250,"MSTRG.5285","PPCDC","GO:0003824(catalytic activity);GO:0016829(lyase activity);GO:0005515(protein binding);GO:0016831(carboxy-lyase activity);GO:0042802(identical protein binding);GO:0005829(cytosol);GO:0009108(coenzyme biosynthetic process);GO:0015937(coenzyme A biosynthetic process);GO:0004633(phosphopantothenoylcysteine decarboxylase activity)","00770(Pantothenate and CoA biosynthesis)","K01598","EC:4.1.1.36","phosphopantothenoylcysteine decarboxylase [Source:HGNC Symbol;Acc:HGNC:28107]",{"v":3.164615,"d":"3.16"},{"v":0.423365,"d":"0.42"},{"v":7.47490935717407,"d":"7.47"},{"v":2.90205608489625,"d":"2.90"},{"v":0.000170615421813101,"d":"0.00"},{"v":0.00597444450962564,"d":"0.01"},"up","yes"]
[163270,0,"chr6","-",24804285,24910967,"ENST00000259698",23,5471,"MSTRG.12716","RIPOR2","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0007155(cell adhesion);GO:0007605(sensory perception of sound);GO:0048741(skeletal muscle fiber development);GO:0005886(plasma membrane);GO:0005856(cytoskeleton);GO:0042995(cell projection);GO:0005515(protein binding);GO:0007275(multicellular organism development);GO:0030154(cell differentiation);GO:0006935(chemotaxis);GO:2000114(regulation of establishment of cell polarity);GO:0030175(filopodium);GO:0032420(stereocilium);GO:0007517(muscle organ development);GO:0060171(stereocilium membrane);GO:0016324(apical plasma membrane);GO:0051491(positive regulation of filopodium assembly);GO:0007162(negative regulation of cell adhesion);GO:0009968(negative regulation of signal transduction);GO:1901741(positive regulation of myoblast fusion);GO:0071889(14-3-3 protein binding);GO:2000405(negative regulation of T cell migration);GO:0090023(positive regulation of neutrophil chemotaxis);GO:0045663(positive regulation of myoblast differentiation);GO:1990869(cellular response to chemokine);GO:0035024(negative regulation of Rho protein signal transduction);GO:1903904(negative regulation of establishment of T cell polarity);GO:1905872(negative regulation of protein localization to cell leading edge);GO:2000391(positive regulation of neutrophil extravasation);GO:2001107(negative regulation of Rho guanyl-nucleotide exchange factor activity)","NA","NA","NA","RHO family interacting cell polarization regulator 2 [Source:HGNC Symbol;Acc:HGNC:13872]",{"v":4.331111,"d":"4.33"},{"v":0.609648,"d":"0.61"},{"v":7.10428148702202,"d":"7.10"},{"v":2.82868874552323,"d":"2.83"},{"v":0.000170632460970144,"d":"0.00"},{"v":0.00597444450962564,"d":"0.01"},"up","yes"]
[162271,0,"chr5","-",181236937,181243902,"ENST00000508682",9,1208,"MSTRG.12625","RACK1","GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0016567(protein ubiquitination);GO:0030529(intracellular ribonucleoprotein complex);GO:0005840(ribosome);GO:0005739(mitochondrion);GO:0005886(plasma membrane);GO:0042995(cell projection);GO:0005515(protein binding);GO:0007049(cell cycle);GO:0048511(rhythmic process);GO:0006915(apoptotic process);GO:0007275(multicellular organism development);GO:0048471(perinuclear region of cytoplasm);GO:0065009(regulation of molecular function);GO:0043022(ribosome binding);GO:0030425(dendrite);GO:0030496(midbody);GO:0045296(cadherin binding);GO:2000114(regulation of establishment of cell polarity);GO:0043204(perikaryon);GO:0070062(extracellular exosome);GO:0001934(positive regulation of protein phosphorylation);GO:0001891(phagocytic cup);GO:0043547(positive regulation of GTPase activity);GO:0042169(SH2 domain binding);GO:0040008(regulation of growth);GO:0032947(protein complex scaffold);GO:0006417(regulation of translation);GO:0030178(negative regulation of Wnt signaling pathway);GO:0030335(positive regulation of cell migration);GO:0043065(positive regulation of apoptotic process);GO:0016032(viral process);GO:0005102(receptor binding);GO:0017148(negative regulation of translation);GO:0008200(ion channel inhibitor activity);GO:0006412(translation);GO:0043473(pigmentation);GO:1903208(negative regulation of hydrogen peroxide-induced neuron death);GO:0043005(neuron projection);GO:0043025(neuronal cell body);GO:0044297(cell body);GO:0010629(negative regulation of gene expression);GO:0019903(protein phosphatase binding);GO:0030308(negative regulation of cell growth);GO:0042803(protein homodimerization activity);GO:0051726(regulation of cell cycle);GO:2001244(positive regulation of intrinsic apoptotic signaling pathway);GO:0030971(receptor tyrosine kinase binding);GO:0051302(regulation of cell division);GO:0019899(enzyme binding);GO:0008656(cysteine-type endopeptidase activator activity involved in apoptotic process);GO:0006919(activation of cysteine-type endopeptidase activity involved in apoptotic process);GO:0051898(negative regulation of protein kinase B signaling);GO:0071333(cellular response to glucose stimulus);GO:0010803(regulation of tumor necrosis factor-mediated signaling pathway);GO:0071363(cellular response to growth factor stimulus);GO:0032880(regulation of protein localization);GO:0033137(negative regulation of peptidyl-serine phosphorylation);GO:0050765(negative regulation of phagocytosis);GO:2000304(positive regulation of ceramide biosynthetic process);GO:0032436(positive regulation of proteasomal ubiquitin-dependent protein catabolic process);GO:1990630(IRE1-RACK1-PP2A complex);GO:0030822(positive regulation of cAMP catabolic process);GO:0042998(positive regulation of Golgi to plasma membrane protein transport);GO:0030292(protein tyrosine kinase inhibitor activity);GO:0061099(negative regulation of protein tyrosine kinase activity);GO:0007369(gastrulation);GO:0005080(protein kinase C binding);GO:0032464(positive regulation of protein homooligomerization);GO:2000543(positive regulation of gastrulation);GO:0015935(small ribosomal subunit);GO:0035591(signaling adaptor activity);GO:0051343(positive regulation of cyclic-nucleotide phosphodiesterase activity);GO:0051901(positive regulation of mitochondrial depolarization);GO:0072344(rescue of stalled ribosome);GO:1900102(negative regulation of endoplasmic reticulum unfolded protein response)","05162(Measles)","NA","NA","receptor for activated C kinase 1 [Source:HGNC Symbol;Acc:HGNC:4399]",{"v":1.9114,"d":"1.91"},{"v":10.471921,"d":"10.47"},{"v":0.182526205077368,"d":"0.18"},{"v":-2.45382448995685,"d":"-2.45"},{"v":0.000170888194483935,"d":"0.00"},{"v":0.00597444450962564,"d":"0.01"},"down","yes"]
[92362,"j","chr18","-",49488481,49492547,"MSTRG.7521.11",7,1145,"MSTRG.7521","RPL17-C18orf32","NA","NA","NA","NA","NA",{"v":49.952805,"d":"49.95"},{"v":264.44278,"d":"264.44"},{"v":0.188898350713149,"d":"0.19"},{"v":-2.40431798939374,"d":"-2.40"},{"v":1.71233968424122E-4,"d":"0.00"},{"v":0.00597597489801857,"d":"0.01"},"down","yes"]
[131656,0,"chr22","+",41091786,41180079,"ENST00000263253",31,9587,"MSTRG.10492","EP300","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0016740(transferase activity);GO:0003713(transcription coactivator activity);GO:0006355(regulation of transcription, DNA-templated);GO:0006366(transcription from RNA polymerase II promoter);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0016746(transferase activity, transferring acyl groups);GO:0005515(protein binding);GO:0000123(histone acetyltransferase complex);GO:0007049(cell cycle);GO:0007623(circadian rhythm);GO:0048511(rhythmic process);GO:0006915(apoptotic process);GO:0004402(histone acetyltransferase activity);GO:0003712(transcription cofactor activity);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0016573(histone acetylation);GO:0001047(core promoter binding);GO:0006977(DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0045444(fat cell differentiation);GO:0031648(protein destabilization);GO:0050821(protein stabilization);GO:0002223(stimulatory C-type lectin receptor signaling pathway);GO:0016579(protein deubiquitination);GO:0061418(regulation of transcription from RNA polymerase II promoter in response to hypoxia);GO:0003682(chromatin binding);GO:0001666(response to hypoxia);GO:0016032(viral process);GO:0007399(nervous system development);GO:0045815(positive regulation of gene expression, epigenetic);GO:0008134(transcription factor binding);GO:0043967(histone H4 acetylation);GO:1904837(beta-catenin-TCF complex assembly);GO:1901796(regulation of signal transduction by p53 class mediator);GO:0007219(Notch signaling pathway);GO:0051091(positive regulation of sequence-specific DNA binding transcription factor activity);GO:0001102(RNA polymerase II activating transcription factor binding);GO:0043627(response to estrogen);GO:0045652(regulation of megakaryocyte differentiation);GO:0032481(positive regulation of type I interferon production);GO:0008013(beta-catenin binding);GO:0042771(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator);GO:1900034(regulation of cellular response to heat);GO:0006283(transcription-coupled nucleotide-excision repair);GO:0003684(damaged DNA binding);GO:0035257(nuclear hormone receptor binding);GO:0050681(androgen receptor binding);GO:0008022(protein C-terminus binding);GO:0051726(regulation of cell cycle);GO:0034644(cellular response to UV);GO:0010506(regulation of autophagy);GO:0006990(positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response);GO:0060765(regulation of androgen receptor signaling pathway);GO:0006475(internal protein amino acid acetylation);GO:0010742(macrophage derived foam cell differentiation);GO:0016407(acetyltransferase activity);GO:0006473(protein acetylation);GO:0018393(internal peptidyl-lysine acetylation);GO:0043923(positive regulation by host of viral transcription);GO:0033613(activating transcription factor binding);GO:0000979(RNA polymerase II core promoter sequence-specific DNA binding);GO:0001085(RNA polymerase II transcription factor binding);GO:0001228(transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding);GO:0002039(p53 binding);GO:0004468(lysine N-acetyltransferase activity, acting on acetyl phosphate as donor);GO:0031490(chromatin DNA binding);GO:0034212(peptide N-acetyltransferase activity);GO:0061733(peptide-lysine-N-acetyltransferase activity);GO:0097157(pre-mRNA intronic binding);GO:0001756(somitogenesis);GO:0007507(heart development);GO:0007519(skeletal muscle tissue development);GO:0009887(animal organ morphogenesis);GO:0010628(positive regulation of gene expression);GO:0018076(N-terminal peptidyl-lysine acetylation);GO:0030183(B cell differentiation);GO:0030220(platelet formation);GO:0030324(lung development);GO:0032092(positive regulation of protein binding);GO:0035855(megakaryocyte development);GO:0043969(histone H2B acetylation);GO:0045893(positive regulation of transcription, DNA-templated);GO:0090043(regulation of tubulin deacetylation);GO:0005667(transcription factor complex);GO:0043234(protein complex)","04310(Wnt signaling pathway);04330(Notch signaling pathway);04350(TGF-beta signaling pathway);04630(Jak-STAT signaling pathway);04066(HIF-1 signaling pathway);04068(FoxO signaling pathway);04024(cAMP signaling pathway);04110(Cell cycle);04520(Adherens junction);04922(Glucagon signaling pathway);04919(Thyroid hormone signaling pathway);04916(Melanogenesis);04720(Long-term potentiation);05200(Pathways in cancer);05206(MicroRNAs in cancer);05203(Viral carcinogenesis);05211(Renal cell carcinoma);05215(Prostate cancer);05016(Huntington's disease);05152(Tuberculosis);05166(HTLV-I infection);05164(Influenza A);05161(Hepatitis B);05168(Herpes simplex infection);05167(Kaposi's sarcoma-associated herpesvirus infection);05169(Epstein-Barr virus infection);05165(Human papillomavirus infection)","K04498","EC:2.3.1.48","E1A binding protein p300 [Source:HGNC Symbol;Acc:HGNC:3373]",{"v":12.248425,"d":"12.25"},{"v":1.750521,"d":"1.75"},{"v":6.99701688811502,"d":"7.00"},{"v":2.80673997376935,"d":"2.81"},{"v":1.71902367518071E-4,"d":"0.00"},{"v":5.98873952191477E-3,"d":"0.01"},"up","yes"]
[130484,0,"chr22","+",31496538,31618548,"ENST00000400289",31,3739,"MSTRG.10394","SFI1","GO:0005737(cytoplasm);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0005813(centrosome);GO:0005829(cytosol);GO:0005814(centriole);GO:0019902(phosphatase binding);GO:0000086(G2/M transition of mitotic cell cycle);GO:0010389(regulation of G2/M transition of mitotic cell cycle);GO:0010923(negative regulation of phosphatase activity);GO:0097711(ciliary basal body docking)","NA","NA","NA","SFI1 centrin binding protein [Source:HGNC Symbol;Acc:HGNC:29064]",{"v":0.195055,"d":"0.20"},{"v":1.128961,"d":"1.13"},{"v":0.172773904501573,"d":"0.17"},{"v":-2.53304276331864,"d":"-2.53"},{"v":1.73057358886893E-4,"d":"0.00"},{"v":6.01838140185208E-3,"d":"0.01"},"down","yes"]
[162333,0,"chr6","+",292097,351355,"ENST00000344450",8,1485,"MSTRG.12620","DUSP22","GO:0008138(protein tyrosine/serine/threonine phosphatase activity);GO:0016791(phosphatase activity);GO:0006470(protein dephosphorylation);GO:0016311(dephosphorylation);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016787(hydrolase activity);GO:0035335(peptidyl-tyrosine dephosphorylation);GO:0004721(phosphoprotein phosphatase activity);GO:0004725(protein tyrosine phosphatase activity);GO:0007275(multicellular organism development);GO:0006915(apoptotic process);GO:0042127(regulation of cell proliferation);GO:0008283(cell proliferation);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0000188(inactivation of MAPK activity);GO:0007179(transforming growth factor beta receptor signaling pathway);GO:0046330(positive regulation of JNK cascade);GO:0002710(negative regulation of T cell mediated immunity);GO:0050860(negative regulation of T cell receptor signaling pathway);GO:0050868(negative regulation of T cell activation)","NA","NA","NA","dual specificity phosphatase 22 [Source:HGNC Symbol;Acc:HGNC:16077]",{"v":0.794637,"d":"0.79"},{"v":4.452485,"d":"4.45"},{"v":0.178470449647781,"d":"0.18"},{"v":-2.48624287595977,"d":"-2.49"},{"v":1.74096669087793E-4,"d":"0.00"},{"v":0.00604390331212148,"d":"0.01"},"down","yes"]
[177038,"j","chr7","+",100852721,100867010,"MSTRG.13834.4",14,3311,"MSTRG.13834","SLC12A9","NA","NA","NA","NA","NA",{"v":9.05414,"d":"9.05"},{"v":1.282435,"d":"1.28"},{"v":7.0601161072491,"d":"7.06"},{"v":2.81969190955525,"d":"2.82"},{"v":1.75439668383689E-4,"d":"0.00"},{"v":0.00607986017158745,"d":"0.01"},"up","yes"]
[78861,"j","chr17","+",7558441,7571822,"MSTRG.6423.11",16,4857,"MSTRG.6423","SENP3-EIF4A1","NA","NA","NA","NA","NA",{"v":10.160622,"d":"10.16"},{"v":1.449219,"d":"1.45"},{"v":7.01110184175063,"d":"7.01"},{"v":2.80964119127057,"d":"2.81"},{"v":0.000177779350291227,"d":"0.00"},{"v":0.0061469698384081,"d":"0.01"},"up","yes"]
[160796,0,"chr5","+",163505626,163519149,"ENST00000523606",6,3210,"MSTRG.12524","MAT2B","GO:0005634(nucleus);GO:0006730(one-carbon metabolic process);GO:0050790(regulation of catalytic activity);GO:0005515(protein binding);GO:0006556(S-adenosylmethionine biosynthetic process);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0005622(intracellular);GO:0019899(enzyme binding);GO:0032259(methylation);GO:0048269(methionine adenosyltransferase complex);GO:0048270(methionine adenosyltransferase regulator activity);GO:0005739(mitochondrion)","00270(Cysteine and methionine metabolism)","NA","NA","methionine adenosyltransferase 2B [Source:HGNC Symbol;Acc:HGNC:6905]",{"v":0.434638,"d":"0.43"},{"v":2.39733,"d":"2.40"},{"v":0.181300863877731,"d":"0.18"},{"v":-2.46354229551324,"d":"-2.46"},{"v":0.000178171763020431,"d":"0.00"},{"v":0.0061469698384081,"d":"0.01"},"down","yes"]
[37265,0,"chr12","+",752593,911300,"ENST00000535572",26,9886,"MSTRG.3007","WNK1","GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0005829(cytosol);GO:0005737(cytoplasm);GO:0000166(nucleotide binding);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0006811(ion transport);GO:0005515(protein binding);GO:0004860(protein kinase inhibitor activity);GO:0071901(negative regulation of protein serine/threonine kinase activity);GO:0032147(activation of protein kinase activity);GO:0048666(neuron development);GO:0019902(phosphatase binding);GO:0010923(negative regulation of phosphatase activity);GO:0006469(negative regulation of protein kinase activity);GO:0035556(intracellular signal transduction);GO:0016020(membrane);GO:0019869(chloride channel inhibitor activity);GO:0002028(regulation of sodium ion transport);GO:0019901(protein kinase binding);GO:0018107(peptidyl-threonine phosphorylation);GO:0030295(protein kinase activator activity);GO:0023016(signal transduction by trans-phosphorylation);GO:0050794(regulation of cellular process);GO:0000287(magnesium ion binding);GO:0019870(potassium channel inhibitor activity);GO:0030291(protein serine/threonine kinase inhibitor activity);GO:0003084(positive regulation of systemic arterial blood pressure);GO:0033673(negative regulation of kinase activity);GO:0046777(protein autophosphorylation);GO:0071277(cellular response to calcium ion);GO:0090188(negative regulation of pancreatic juice secretion)","NA","NA","NA","WNK lysine deficient protein kinase 1 [Source:HGNC Symbol;Acc:HGNC:14540]",{"v":3.736946,"d":"3.74"},{"v":0.53115,"d":"0.53"},{"v":7.03557563776711,"d":"7.04"},{"v":2.81466846692695,"d":"2.81"},{"v":0.000178314006788679,"d":"0.00"},{"v":0.0061469698384081,"d":"0.01"},"up","yes"]
[7331,0,"chr1","+",75724706,75762954,"ENST00000526196",11,1451,"MSTRG.655","ACADM","GO:0005634(nucleus);GO:0016607(nuclear speck);GO:0016491(oxidoreductase activity);GO:0050660(flavin adenine dinucleotide binding);GO:0055114(oxidation-reduction process);GO:0016627(oxidoreductase activity, acting on the CH-CH group of donors);GO:0005739(mitochondrion);GO:0006629(lipid metabolic process);GO:0008152(metabolic process);GO:0006631(fatty acid metabolic process);GO:0005759(mitochondrial matrix);GO:0003995(acyl-CoA dehydrogenase activity);GO:0006635(fatty acid beta-oxidation);GO:0070991(medium-chain-acyl-CoA dehydrogenase activity);GO:0030424(axon);GO:0070062(extracellular exosome);GO:0042802(identical protein binding);GO:0019216(regulation of lipid metabolic process);GO:0019254(carnitine metabolic process, CoA-linked);GO:0033539(fatty acid beta-oxidation using acyl-CoA dehydrogenase);GO:0045329(carnitine biosynthetic process);GO:0051791(medium-chain fatty acid metabolic process);GO:0051793(medium-chain fatty acid catabolic process);GO:0001889(liver development);GO:0005978(glycogen biosynthetic process);GO:0006082(organic acid metabolic process);GO:0006111(regulation of gluconeogenesis);GO:0007507(heart development);GO:0009409(response to cold);GO:0009437(carnitine metabolic process);GO:0009791(post-embryonic development);GO:0042594(response to starvation);GO:0055007(cardiac muscle cell differentiation)","00640(Propanoate metabolism);00071(Fatty acid degradation);00280(Valine, leucine and isoleucine degradation);00410(beta-Alanine metabolism);03320(PPAR signaling pathway)","NA","NA","acyl-CoA dehydrogenase, C-4 to C-12 straight chain [Source:HGNC Symbol;Acc:HGNC:89]",{"v":6.433796,"d":"6.43"},{"v":0.886669,"d":"0.89"},{"v":7.25614180714562,"d":"7.26"},{"v":2.85920265080395,"d":"2.86"},{"v":0.000178727371780988,"d":"0.00"},{"v":0.0061469698384081,"d":"0.01"},"up","yes"]
[61697,0,"chr15","+",43185940,43195192,"ENST00000444658",9,1479,"MSTRG.5021","CCNDBP1","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005654(nucleoplasm);GO:0005515(protein binding);GO:0007049(cell cycle);GO:0051726(regulation of cell cycle)","NA","NA","NA","cyclin D1 binding protein 1 [Source:HGNC Symbol;Acc:HGNC:1587]",{"v":3.932681,"d":"3.93"},{"v":0.524489,"d":"0.52"},{"v":7.49811912165937,"d":"7.50"},{"v":2.90652874571964,"d":"2.91"},{"v":1.78929382803874E-4,"d":"0.00"},{"v":0.0061469698384081,"d":"0.01"},"up","yes"]
[174788,0,"chr7","+",72925122,72946234,"ENST00000434423",13,3750,"MSTRG.13679","POM121","GO:0006810(transport);GO:0051028(mRNA transport);GO:0005634(nucleus);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0015031(protein transport);GO:0005654(nucleoplasm);GO:0031965(nuclear membrane);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005515(protein binding);GO:0005643(nuclear pore);GO:0075733(intracellular transport of virus);GO:0043657(host cell);GO:0008139(nuclear localization sequence binding);GO:0016032(viral process);GO:0006406(mRNA export from nucleus);GO:0016925(protein sumoylation);GO:0006606(protein import into nucleus);GO:0060964(regulation of gene silencing by miRNA);GO:0006110(regulation of glycolytic process);GO:0006409(tRNA export from nucleus);GO:0007077(mitotic nuclear envelope disassembly);GO:0019083(viral transcription);GO:1900034(regulation of cellular response to heat);GO:0017056(structural constituent of nuclear pore);GO:0006405(RNA export from nucleus);GO:0005635(nuclear envelope);GO:0005487(nucleocytoplasmic transporter activity)","03013(RNA transport)","K14316","NA","POM121 transmembrane nucleoporin [Source:HGNC Symbol;Acc:HGNC:19702]",{"v":4.850292,"d":"4.85"},{"v":0.6821,"d":"0.68"},{"v":7.11082246004985,"d":"7.11"},{"v":2.8300164361333,"d":"2.83"},{"v":0.000179349724133357,"d":"0.00"},{"v":0.00615073196040012,"d":"0.01"},"up","yes"]
[42680,0,"chr12","+",55743280,55757278,"ENST00000257868",3,8657,"MSTRG.3433","GDF11","GO:0043231(intracellular membrane-bounded organelle);GO:0005654(nucleoplasm);GO:0008083(growth factor activity);GO:0005576(extracellular region);GO:0005125(cytokine activity);GO:0005615(extracellular space);GO:0007399(nervous system development);GO:0001501(skeletal system development);GO:0001656(metanephros development);GO:0001657(ureteric bud development);GO:0008285(negative regulation of cell proliferation);GO:0009887(animal organ morphogenesis);GO:0009952(anterior/posterior pattern specification);GO:0021512(spinal cord anterior/posterior patterning);GO:0031016(pancreas development);GO:0045596(negative regulation of cell differentiation);GO:0048469(cell maturation);GO:0048593(camera-type eye morphogenesis);GO:0060021(palate development);GO:0060395(SMAD protein signal transduction);GO:0005515(protein binding);GO:0005575(cellular_component);GO:0043234(protein complex);GO:0005160(transforming growth factor beta receptor binding);GO:0010862(positive regulation of pathway-restricted SMAD protein phosphorylation);GO:0042981(regulation of apoptotic process);GO:0043408(regulation of MAPK cascade);GO:0048468(cell development);GO:0007498(mesoderm development)","NA","NA","NA","growth differentiation factor 11 [Source:HGNC Symbol;Acc:HGNC:4216]",{"v":1.24188,"d":"1.24"},{"v":0.17128,"d":"0.17"},{"v":7.25058383932742,"d":"7.25"},{"v":2.8580971700502,"d":"2.86"},{"v":0.00018001638002151,"d":"0.00"},{"v":0.00616291371603052,"d":"0.01"},"up","yes"]
[127061,0,"chr21","+",37085790,37203112,"ENST00000479930",44,8998,"MSTRG.10051","TTC3","GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0005730(nucleolus);GO:0005829(cytosol);GO:0016740(transferase activity);GO:0016567(protein ubiquitination);GO:0006511(ubiquitin-dependent protein catabolic process);GO:0005515(protein binding);GO:0004842(ubiquitin-protein transferase activity);GO:0070936(protein K48-linked ubiquitination)","NA","NA","NA","tetratricopeptide repeat domain 3 [Source:HGNC Symbol;Acc:HGNC:12393]",{"v":0.356815,"d":"0.36"},{"v":1.911139,"d":"1.91"},{"v":0.186702798697531,"d":"0.19"},{"v":-2.42118454098803,"d":"-2.42"},{"v":0.000180998847815928,"d":"0.00"},{"v":0.00618584663312881,"d":"0.01"},"down","yes"]
[103968,"j","chr19","-",49555718,49580579,"MSTRG.8321.6",9,1262,"MSTRG.8321","NOSIP","NA","NA","NA","NA","NA",{"v":1.079169,"d":"1.08"},{"v":5.964009,"d":"5.96"},{"v":0.180946910039874,"d":"0.18"},{"v":-2.46636162330961,"d":"-2.47"},{"v":0.000182226189858155,"d":"0.00"},{"v":6.20876677262898E-3,"d":"0.01"},"down","yes"]
[179460,0,"chr7","+",142111754,142222324,"ENST00000477922",48,7867,"ENSG00000257743","MGAM2","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0030246(carbohydrate binding);GO:0003824(catalytic activity);GO:0005975(carbohydrate metabolic process);GO:0004553(hydrolase activity, hydrolyzing O-glycosyl compounds);GO:0004339(glucan 1,4-alpha-glucosidase activity)","00052(Galactose metabolism);00500(Starch and sucrose metabolism);04973(Carbohydrate digestion and absorption)","K12047","EC:3.2.1.20;EC:3.2.1.3","maltase-glucoamylase 2 (putative) [Source:HGNC Symbol;Acc:HGNC:28101]",{"v":0.759491,"d":"0.76"},{"v":0.101982,"d":"0.10"},{"v":7.4473044262713,"d":"7.45"},{"v":2.89671833234479,"d":"2.90"},{"v":0.000182297023190693,"d":"0.00"},{"v":6.20876677262898E-3,"d":"0.01"},"up","yes"]
[2820,0,"chr1","+",24643308,24671595,"ENST00000479034",17,2671,"MSTRG.255","SRRM1","GO:0006397(mRNA processing);GO:0003723(RNA binding);GO:0008380(RNA splicing);GO:0005634(nucleus);GO:0016607(nuclear speck);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0005681(spliceosomal complex);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0000398(mRNA splicing, via spliceosome);GO:0006369(termination of RNA polymerase II transcription);GO:0006405(RNA export from nucleus);GO:0031124(mRNA 3'-end processing);GO:0016363(nuclear matrix);GO:0000375(RNA splicing, via transesterification reactions);GO:0006406(mRNA export from nucleus);GO:0071013(catalytic step 2 spliceosome)","03013(RNA transport);03015(mRNA surveillance pathway)","NA","NA","serine and arginine repetitive matrix 1 [Source:HGNC Symbol;Acc:HGNC:16638]",{"v":2.517314,"d":"2.52"},{"v":0.337888,"d":"0.34"},{"v":7.45014324273132,"d":"7.45"},{"v":2.8972681643119,"d":"2.90"},{"v":1.8307837992406E-4,"d":"0.00"},{"v":6.22466491741803E-3,"d":"0.01"},"up","yes"]
[35485,0,"chr11","+",117144267,117171048,"ENST00000527958",6,4198,"MSTRG.2864","PAFAH1B2","GO:0005737(cytoplasm);GO:0005730(nucleolus);GO:0005829(cytosol);GO:0016787(hydrolase activity);GO:0001650(fibrillar center);GO:0006629(lipid metabolic process);GO:0016042(lipid catabolic process);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0070062(extracellular exosome);GO:0043312(neutrophil degranulation);GO:0034774(secretory granule lumen);GO:1904813(ficolin-1-rich granule lumen);GO:0016239(positive regulation of macroautophagy);GO:0007420(brain development);GO:0004623(phospholipase A2 activity);GO:0003847(1-alkyl-2-acetylglycerophosphocholine esterase activity);GO:0042803(protein homodimerization activity);GO:0046982(protein heterodimerization activity);GO:0047179(platelet-activating factor acetyltransferase activity);GO:0007283(spermatogenesis)","00565(Ether lipid metabolism)","K16795","EC:3.1.1.47","platelet activating factor acetylhydrolase 1b catalytic subunit 2 [Source:HGNC Symbol;Acc:HGNC:8575]",{"v":11.081309,"d":"11.08"},{"v":1.586733,"d":"1.59"},{"v":6.98372631060172,"d":"6.98"},{"v":2.80399702144236,"d":"2.80"},{"v":0.000184391030745341,"d":"0.00"},{"v":0.00625854153754511,"d":"0.01"},"up","yes"]
[196831,"j","chrX","-",47651796,47659169,"MSTRG.15260.1",7,562,"MSTRG.15260","UXT","NA","NA","NA","NA","NA",{"v":1.552109,"d":"1.55"},{"v":8.834414,"d":"8.83"},{"v":0.175688959109229,"d":"0.18"},{"v":-2.50890456454766,"d":"-2.51"},{"v":0.00018858566370027,"d":"0.00"},{"v":0.00638995396113174,"d":"0.01"},"down","yes"]
[187979,0,"chr8","-",143579722,143597396,"ENST00000532400",4,419,"MSTRG.14619","EEF1D","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0006412(translation);GO:0005829(cytosol);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0001650(fibrillar center);GO:0005783(endoplasmic reticulum);GO:0005515(protein binding);GO:0004871(signal transducer activity);GO:0003746(translation elongation factor activity);GO:0006414(translational elongation);GO:0005853(eukaryotic translation elongation factor 1 complex);GO:0007165(signal transduction);GO:0045296(cadherin binding);GO:0043123(positive regulation of I-kappaB kinase/NF-kappaB signaling);GO:0008135(translation factor activity, RNA binding);GO:0071479(cellular response to ionizing radiation)","05168(Herpes simplex infection)","NA","NA","eukaryotic translation elongation factor 1 delta [Source:HGNC Symbol;Acc:HGNC:3211]",{"v":1.938961,"d":"1.94"},{"v":10.921258,"d":"10.92"},{"v":0.177540078258384,"d":"0.18"},{"v":-2.49378335659204,"d":"-2.49"},{"v":0.000192149665139136,"d":"0.00"},{"v":0.00649958559619356,"d":"0.01"},"down","yes"]
[64843,0,"chr15","+",75201877,75212169,"ENST00000394987",3,4430,"MSTRG.5289","C15orf39","GO:0005829(cytosol)","NA","NA","NA","chromosome 15 open reading frame 39 [Source:HGNC Symbol;Acc:HGNC:24497]",{"v":38.050781,"d":"38.05"},{"v":5.528073,"d":"5.53"},{"v":6.8831907610482,"d":"6.88"},{"v":2.7830774934198,"d":"2.78"},{"v":0.000193251154805079,"d":"0.00"},{"v":0.00652568916601177,"d":"0.01"},"up","yes"]
[170455,0,"chr6","-",157289386,157323601,"ENST00000400788",4,4043,"ENSG00000215712","TMEM242","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005515(protein binding)","NA","NA","NA","transmembrane protein 242 [Source:HGNC Symbol;Acc:HGNC:17206]",{"v":0.250495,"d":"0.25"},{"v":1.380392,"d":"1.38"},{"v":0.181466568916656,"d":"0.18"},{"v":-2.46222430589828,"d":"-2.46"},{"v":0.000194768111076799,"d":"0.00"},{"v":0.00656570933899097,"d":"0.01"},"down","yes"]
[65804,0,"chr15","-",83127753,83208018,"ENST00000299633",6,12733,"ENSG00000166503","HDGFL3","GO:0005654(nucleoplasm);GO:0005634(nucleus);GO:0008083(growth factor activity);GO:0005829(cytosol);GO:0008017(microtubule binding);GO:0015631(tubulin binding);GO:0007026(negative regulation of microtubule depolymerization);GO:0031175(neuron projection development);GO:0046785(microtubule polymerization);GO:0005737(cytoplasm);GO:0008283(cell proliferation)","NA","NA","NA","HDGF like 3 [Source:HGNC Symbol;Acc:HGNC:24937]",{"v":0.063408,"d":"0.06"},{"v":0.359213,"d":"0.36"},{"v":0.176519223970179,"d":"0.18"},{"v":-2.50210278495366,"d":"-2.50"},{"v":1.95891300687894E-4,"d":"0.00"},{"v":0.00659234193539465,"d":"0.01"},"down","yes"]
[98453,0,"chr19","+",17860125,17863243,"ENST00000597648",5,683,"MSTRG.7977","RPL18A","GO:0003723(RNA binding);GO:0016020(membrane);GO:0006412(translation);GO:0030529(intracellular ribonucleoprotein complex);GO:0003735(structural constituent of ribosome);GO:0005840(ribosome);GO:0005829(cytosol);GO:0005515(protein binding);GO:0006413(translational initiation);GO:0006364(rRNA processing);GO:0000184(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay);GO:0019083(viral transcription);GO:0006614(SRP-dependent cotranslational protein targeting to membrane);GO:0022625(cytosolic large ribosomal subunit);GO:0097327(response to antineoplastic agent)","03010(Ribosome)","NA","NA","ribosomal protein L18a [Source:HGNC Symbol;Acc:HGNC:10311]",{"v":31.13106,"d":"31.13"},{"v":4.452457,"d":"4.45"},{"v":6.99188335788532,"d":"6.99"},{"v":2.805681117275,"d":"2.81"},{"v":1.97015273483006E-4,"d":"0.00"},{"v":0.00661891041032551,"d":"0.01"},"up","yes"]
[179336,0,"chr7","+",140696672,140706646,"ENST00000247866",4,504,"MSTRG.14017","NDUFB2","GO:0005743(mitochondrial inner membrane);GO:0005747(mitochondrial respiratory chain complex I);GO:0016020(membrane);GO:0055114(oxidation-reduction process);GO:0005739(mitochondrion);GO:0070469(respiratory chain);GO:0032981(mitochondrial respiratory chain complex I assembly);GO:0008137(NADH dehydrogenase (ubiquinone) activity);GO:0006120(mitochondrial electron transport, NADH to ubiquinone)","00190(Oxidative phosphorylation);04723(Retrograde endocannabinoid signaling);05010(Alzheimer's disease);05012(Parkinson's disease);05016(Huntington's disease);04932(Non-alcoholic fatty liver disease (NAFLD))","K03958","NA","NADH:ubiquinone oxidoreductase subunit B2 [Source:HGNC Symbol;Acc:HGNC:7697]",{"v":6.733768,"d":"6.73"},{"v":35.693966,"d":"35.69"},{"v":0.188652838409719,"d":"0.19"},{"v":-2.40619428825209,"d":"-2.41"},{"v":0.000198238999467415,"d":"0.00"},{"v":0.00664873444315459,"d":"0.01"},"down","yes"]
[199841,0,"chrX","+",124346344,124373155,"ENST00000371139",4,2450,"MSTRG.15443","SH2D1A","GO:0005737(cytoplasm);GO:0009967(positive regulation of signal transduction);GO:0005515(protein binding);GO:0002376(immune system process);GO:0045087(innate immune response);GO:0002250(adaptive immune response);GO:0050776(regulation of immune response);GO:0005070(SH3/SH2 adaptor activity);GO:0005829(cytosol);GO:0007267(cell-cell signaling);GO:0006959(humoral immune response);GO:0006968(cellular defense response);GO:0045954(positive regulation of natural killer cell mediated cytotoxicity)","04650(Natural killer cell mediated cytotoxicity);05162(Measles)","K07990","NA","SH2 domain containing 1A [Source:HGNC Symbol;Acc:HGNC:10820]",{"v":2.916014,"d":"2.92"},{"v":15.248256,"d":"15.25"},{"v":0.191235902650113,"d":"0.19"},{"v":-2.3865746944096,"d":"-2.39"},{"v":1.99146524274616E-4,"d":"0.00"},{"v":0.00666787042698156,"d":"0.01"},"down","yes"]
[141712,0,"chr3","+",150603291,150627693,"ENST00000477889",7,944,"MSTRG.11274","SELENOT","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0045454(cell redox homeostasis);GO:0007204(positive regulation of cytosolic calcium ion concentration);GO:0042593(glucose homeostasis);GO:0009749(response to glucose);GO:0060124(positive regulation of growth hormone secretion);GO:0008430(selenium binding);GO:0098869(cellular oxidant detoxification);GO:0004791(thioredoxin-disulfide reductase activity);GO:0001514(selenocysteine incorporation);GO:0031016(pancreas development);GO:0035773(insulin secretion involved in cellular response to glucose stimulus)","NA","NA","NA","selenoprotein T [Source:HGNC Symbol;Acc:HGNC:18136]",{"v":0.860818,"d":"0.86"},{"v":4.832082,"d":"4.83"},{"v":0.178146397350045,"d":"0.18"},{"v":-2.48886478670539,"d":"-2.49"},{"v":0.00019971288674416,"d":"0.00"},{"v":0.00667553818056323,"d":"0.01"},"down","yes"]
[145003,0,"chr4","+",705765,770640,"ENST00000362003",11,5685,"ENSG00000185619","PCGF3","GO:0046872(metal ion binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0005515(protein binding);GO:0031519(PcG protein complex);GO:0016020(membrane);GO:0016021(integral component of membrane)","04550(Signaling pathways regulating pluripotency of stem cells)","K11488","NA","polycomb group ring finger 3 [Source:HGNC Symbol;Acc:HGNC:10066]",{"v":3.164481,"d":"3.16"},{"v":0.451872,"d":"0.45"},{"v":7.00304732313576,"d":"7.00"},{"v":2.80798283653135,"d":"2.81"},{"v":0.000201993390575992,"d":"0.00"},{"v":0.00674037978535873,"d":"0.01"},"up","yes"]
[156487,0,"chr5","-",88195206,88268848,"ENST00000296595",12,2594,"ENSG00000164180","TMEM161B","GO:0003676(nucleic acid binding);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0015074(DNA integration)","NA","NA","NA","transmembrane protein 161B [Source:HGNC Symbol;Acc:HGNC:28483]",{"v":2.202474,"d":"2.20"},{"v":0.299278,"d":"0.30"},{"v":7.35929136120931,"d":"7.36"},{"v":2.8795668533897,"d":"2.88"},{"v":2.02400755495803E-4,"d":"0.00"},{"v":0.00674260294570867,"d":"0.01"},"up","yes"]
[61771,0,"chr15","+",43517625,43531620,"ENST00000300231",6,10258,"ENSG00000166963","MAP1A","GO:0008017(microtubule binding);GO:0000226(microtubule cytoskeleton organization);GO:0005874(microtubule);GO:0005737(cytoplasm);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0005875(microtubule associated complex);GO:0005198(structural molecule activity)","NA","NA","NA","microtubule associated protein 1A [Source:HGNC Symbol;Acc:HGNC:6835]",{"v":0.66928,"d":"0.67"},{"v":0.091581,"d":"0.09"},{"v":7.30806608357629,"d":"7.31"},{"v":2.86948967967103,"d":"2.87"},{"v":0.000203171746033164,"d":"0.00"},{"v":0.00675691178236009,"d":"0.01"},"up","yes"]
[156246,0,"chr5","-",80626228,80654983,"ENST00000439211",6,3917,"MSTRG.12161","DHFR","GO:0003723(RNA binding);GO:0005737(cytoplasm);GO:0009165(nucleotide biosynthetic process);GO:0016491(oxidoreductase activity);GO:0050661(NADP binding);GO:0055114(oxidation-reduction process);GO:0005739(mitochondrion);GO:0006730(one-carbon metabolic process);GO:0005515(protein binding);GO:0006545(glycine biosynthetic process);GO:0003729(mRNA binding);GO:0005575(cellular_component);GO:0005829(cytosol);GO:0004146(dihydrofolate reductase activity);GO:0008144(drug binding);GO:0051000(positive regulation of nitric-oxide synthase activity);GO:0000083(regulation of transcription involved in G1/S transition of mitotic cell cycle);GO:0046655(folic acid metabolic process);GO:0000900(translation repressor activity, nucleic acid binding);GO:0005542(folic acid binding);GO:0033560(folate reductase activity);GO:0051870(methotrexate binding);GO:0070402(NADPH binding);GO:1990825(sequence-specific mRNA binding);GO:0006729(tetrahydrobiopterin biosynthetic process);GO:0017148(negative regulation of translation);GO:0031103(axon regeneration);GO:0031427(response to methotrexate);GO:0046452(dihydrofolate metabolic process);GO:0046653(tetrahydrofolate metabolic process);GO:0046654(tetrahydrofolate biosynthetic process);GO:2000121(regulation of removal of superoxide radicals)","00790(Folate biosynthesis);00670(One carbon pool by folate);01523(Antifolate resistance)","K00287","EC:1.5.1.3","dihydrofolate reductase [Source:HGNC Symbol;Acc:HGNC:2861]",{"v":0.318866,"d":"0.32"},{"v":1.726947,"d":"1.73"},{"v":0.184641451069431,"d":"0.18"},{"v":-2.43720162782315,"d":"-2.44"},{"v":0.000204153911936448,"d":"0.00"},{"v":0.00677818390838664,"d":"0.01"},"down","yes"]
[85424,"u","chr17",".",50150696,50151009,"MSTRG.7007.1",1,314,"MSTRG.7007",".","NA","NA","NA","NA","NA",{"v":26.527411,"d":"26.53"},{"v":3.700911,"d":"3.70"},{"v":7.16780571053992,"d":"7.17"},{"v":2.8415315324514,"d":"2.84"},{"v":2.05569402760505E-4,"d":"0.00"},{"v":0.00681374764124771,"d":"0.01"},"up","yes"]
[28349,0,"chr11","+",44727112,44931332,"ENST00000520358",10,3316,"ENSG00000157570","TSPAN18","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005887(integral component of plasma membrane);GO:0007166(cell surface receptor signaling pathway)","NA","NA","NA","tetraspanin 18 [Source:HGNC Symbol;Acc:HGNC:20660]",{"v":2.442523,"d":"2.44"},{"v":0.339053,"d":"0.34"},{"v":7.20395631361469,"d":"7.20"},{"v":2.84878943244872,"d":"2.85"},{"v":0.000206093413337997,"d":"0.00"},{"v":0.00681969308216102,"d":"0.01"},"up","yes"]
[37872,0,"chr12","+",6534534,6538359,"ENST00000396861",9,1348,"MSTRG.3056","GAPDH","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0043231(intracellular membrane-bounded organelle);GO:0005829(cytosol);GO:0016740(transferase activity);GO:0016491(oxidoreductase activity);GO:0050661(NADP binding);GO:0055114(oxidation-reduction process);GO:0031965(nuclear membrane);GO:0006096(glycolytic process);GO:0030529(intracellular ribonucleoprotein complex);GO:0005886(plasma membrane);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0051287(NAD binding);GO:0006915(apoptotic process);GO:0048471(perinuclear region of cytoplasm);GO:0008017(microtubule binding);GO:0042802(identical protein binding);GO:0004365(glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity);GO:0016620(oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor);GO:0006006(glucose metabolic process);GO:0015630(microtubule cytoskeleton);GO:0070062(extracellular exosome);GO:0050821(protein stabilization);GO:0006417(regulation of translation);GO:0071346(cellular response to interferon-gamma);GO:0031012(extracellular matrix);GO:0061844(antimicrobial humoral immune response mediated by antimicrobial peptide);GO:0017148(negative regulation of translation);GO:0031982(vesicle);GO:0000226(microtubule cytoskeleton organization);GO:0005811(lipid particle);GO:0006094(gluconeogenesis);GO:0061621(canonical glycolysis);GO:0051402(neuron apoptotic process);GO:0031640(killing of cells of other organism);GO:0016241(regulation of macroautophagy);GO:0097452(GAIT complex);GO:0097718(disordered domain specific binding);GO:0010951(negative regulation of endopeptidase activity);GO:0050715(positive regulation of cytokine secretion);GO:0051873(killing by host of symbiont cells);GO:0050832(defense response to fungus);GO:0019828(aspartic-type endopeptidase inhibitor activity);GO:0035605(peptidyl-cysteine S-nitrosylase activity);GO:0035606(peptidyl-cysteine S-trans-nitrosylation);GO:0052501(positive regulation by organism of apoptotic process in other organism involved in symbiotic interaction)","00010(Glycolysis / Gluconeogenesis);04066(HIF-1 signaling pathway);05010(Alzheimer's disease)","K00134","EC:1.2.1.12","glyceraldehyde-3-phosphate dehydrogenase [Source:HGNC Symbol;Acc:HGNC:4141]",{"v":16.378654,"d":"16.38"},{"v":84.654602,"d":"84.65"},{"v":0.193476238893663,"d":"0.19"},{"v":-2.36977169717495,"d":"-2.37"},{"v":0.000206877265226626,"d":"0.00"},{"v":0.00682737705808019,"d":"0.01"},"down","yes"]
[41416,0,"chr12","-",49989164,50025400,"ENST00000454520",17,3080,"ENSG00000161800","RACGAP1","GO:0007165(signal transduction);GO:0006810(transport);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0046872(metal ion binding);GO:0005654(nucleoplasm);GO:0035556(intracellular signal transduction);GO:0051301(cell division);GO:0006811(ion transport);GO:0005886(plasma membrane);GO:0043547(positive regulation of GTPase activity);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0007405(neuroblast proliferation);GO:0045995(regulation of embryonic development);GO:0007049(cell cycle);GO:0007275(multicellular organism development);GO:0030154(cell differentiation);GO:0005874(microtubule);GO:0031410(cytoplasmic vesicle);GO:0005096(GTPase activator activity);GO:0007283(spermatogenesis);GO:0008017(microtubule binding);GO:0005819(spindle);GO:0030496(midbody);GO:0008289(lipid binding);GO:0005829(cytosol);GO:0031234(extrinsic component of cytoplasmic side of plasma membrane);GO:0070062(extracellular exosome);GO:0051056(regulation of small GTPase mediated signal transduction);GO:0019901(protein kinase binding);GO:0006890(retrograde vesicle-mediated transport, Golgi to ER);GO:0032154(cleavage furrow);GO:0051233(spindle midzone);GO:0001669(acrosomal vesicle);GO:0043014(alpha-tubulin binding);GO:0005547(phosphatidylinositol-3,4,5-trisphosphate binding);GO:0007018(microtubule-based movement);GO:0019886(antigen processing and presentation of exogenous peptide antigen via MHC class II);GO:0000281(mitotic cytokinesis);GO:0032467(positive regulation of cytokinesis);GO:0048487(beta-tubulin binding);GO:0072686(mitotic spindle);GO:0043015(gamma-tubulin binding);GO:0051256(mitotic spindle midzone assembly);GO:0051988(regulation of attachment of spindle microtubules to kinetochore);GO:0097149(centralspindlin complex);GO:0008272(sulfate transport);GO:0000915(actomyosin contractile ring assembly)","NA","NA","NA","Rac GTPase activating protein 1 [Source:HGNC Symbol;Acc:HGNC:9804]",{"v":0.268144,"d":"0.27"},{"v":1.496611,"d":"1.50"},{"v":0.179167465694158,"d":"0.18"},{"v":-2.48061940695054,"d":"-2.48"},{"v":0.000207320407055075,"d":"0.00"},{"v":0.00682737705808019,"d":"0.01"},"down","yes"]
[36503,0,"chr11","-",124753123,124762280,"ENST00000417453",7,1833,"MSTRG.2948","ESAM","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0007155(cell adhesion);GO:0005886(plasma membrane);GO:0030054(cell junction);GO:0050900(leukocyte migration);GO:0005923(bicellular tight junction);GO:0070062(extracellular exosome);GO:0005912(adherens junction);GO:0007156(homophilic cell adhesion via plasma membrane adhesion molecules);GO:0016337(single organismal cell-cell adhesion)","04514(Cell adhesion molecules (CAMs));04670(Leukocyte transendothelial migration)","K06787","NA","endothelial cell adhesion molecule [Source:HGNC Symbol;Acc:HGNC:17474]",{"v":4.100123,"d":"4.10"},{"v":0.566561,"d":"0.57"},{"v":7.23686063813076,"d":"7.24"},{"v":2.85536398956914,"d":"2.86"},{"v":0.000207449139233568,"d":"0.00"},{"v":0.00682737705808019,"d":"0.01"},"up","yes"]
[126904,0,"chr21","-",34787801,35049298,"ENST00000437180",9,5967,"MSTRG.10010","RUNX1","GO:0005634(nucleus);GO:0043231(intracellular membrane-bounded organelle);GO:0005524(ATP binding);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0006355(regulation of transcription, DNA-templated);GO:0006366(transcription from RNA polymerase II promoter);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0005515(protein binding);GO:0045893(positive regulation of transcription, DNA-templated);GO:0001047(core promoter binding);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:1902036(regulation of hematopoietic stem cell differentiation);GO:0001228(transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding);GO:2000810(regulation of bicellular tight junction assembly);GO:0030097(hemopoiesis);GO:0000977(RNA polymerase II regulatory region sequence-specific DNA binding);GO:0045766(positive regulation of angiogenesis);GO:0045652(regulation of megakaryocyte differentiation);GO:0030111(regulation of Wnt signaling pathway);GO:0033146(regulation of intracellular estrogen receptor signaling pathway);GO:0032743(positive regulation of interleukin-2 production);GO:0045616(regulation of keratinocyte differentiation);GO:0071425(hematopoietic stem cell proliferation);GO:0045589(regulation of regulatory T cell differentiation);GO:0045637(regulation of myeloid cell differentiation);GO:0001959(regulation of cytokine-mediated signaling pathway);GO:0000975(regulatory region DNA binding);GO:0050855(regulation of B cell receptor signaling pathway);GO:0048935(peripheral nervous system neuron development);GO:0001503(ossification);GO:0002062(chondrocyte differentiation);GO:0030854(positive regulation of granulocyte differentiation)","04530(Tight junction);04659(Th17 cell differentiation);05200(Pathways in cancer);05202(Transcriptional misregulation in cancers);05221(Acute myeloid leukemia);05220(Chronic myeloid leukemia)","K08367","NA","runt related transcription factor 1 [Source:HGNC Symbol;Acc:HGNC:10471]",{"v":4.773296,"d":"4.77"},{"v":0.692331,"d":"0.69"},{"v":6.89452877308686,"d":"6.89"},{"v":2.78545194985921,"d":"2.79"},{"v":2.07705730188209E-4,"d":"0.00"},{"v":0.00682737705808019,"d":"0.01"},"up","yes"]
[126721,0,"chr21","+",33542618,33577481,"ENST00000356577",12,8813,"MSTRG.10037","SON","GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0006397(mRNA processing);GO:0008380(RNA splicing);GO:0005634(nucleus);GO:0016607(nuclear speck);GO:0003677(DNA binding);GO:0007049(cell cycle);GO:0043484(regulation of RNA splicing);GO:0051726(regulation of cell cycle);GO:0005515(protein binding);GO:0043066(negative regulation of apoptotic process);GO:0000226(microtubule cytoskeleton organization);GO:0000281(mitotic cytokinesis);GO:0048024(regulation of mRNA splicing, via spliceosome);GO:0050733(RS domain binding)","NA","NA","NA","SON DNA binding protein [Source:HGNC Symbol;Acc:HGNC:11183]",{"v":4.137267,"d":"4.14"},{"v":0.601658,"d":"0.60"},{"v":6.87644309557921,"d":"6.88"},{"v":2.78166251037716,"d":"2.78"},{"v":0.000210229102994041,"d":"0.00"},{"v":0.00689886150919749,"d":"0.01"},"up","yes"]
[9318,0,"chr1","-",112701131,112707434,"ENST00000369642",5,1355,"MSTRG.813","RHOC","GO:0016020(membrane);GO:0005525(GTP binding);GO:0007264(small GTPase mediated signal transduction);GO:0000166(nucleotide binding);GO:0003924(GTPase activity);GO:0005622(intracellular);GO:0005886(plasma membrane);GO:0044319(wound healing, spreading of cells);GO:1902766(skeletal muscle satellite cell migration);GO:0005515(protein binding);GO:0004871(signal transducer activity);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0051056(regulation of small GTPase mediated signal transduction);GO:0032154(cleavage furrow);GO:0032420(stereocilium);GO:0043123(positive regulation of I-kappaB kinase/NF-kappaB signaling);GO:0000910(cytokinesis);GO:0043297(apical junction assembly);GO:0032464(positive regulation of protein homooligomerization);GO:0060193(positive regulation of lipase activity);GO:0005634(nucleus)","NA","NA","NA","ras homolog family member C [Source:HGNC Symbol;Acc:HGNC:669]",{"v":0.989916,"d":"0.99"},{"v":5.343291,"d":"5.34"},{"v":0.185263351743336,"d":"0.19"},{"v":-2.43235057502958,"d":"-2.43"},{"v":0.000210650714173255,"d":"0.00"},{"v":0.00690125220539795,"d":"0.01"},"down","yes"]
[5505,0,"chr1","-",45511036,45521938,"ENST00000262746",6,1234,"MSTRG.520","PRDX1","GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0045454(cell redox homeostasis);GO:0005515(protein binding);GO:0042470(melanosome);GO:0005615(extracellular space);GO:0004601(peroxidase activity);GO:0051920(peroxiredoxin activity);GO:0016209(antioxidant activity);GO:0005829(cytosol);GO:0045296(cadherin binding);GO:0070062(extracellular exosome);GO:0001895(retina homeostasis);GO:0031012(extracellular matrix);GO:0001501(skeletal system development);GO:0030101(natural killer cell activation);GO:0008283(cell proliferation);GO:0034599(cellular response to oxidative stress);GO:0042744(hydrogen peroxide catabolic process);GO:0008379(thioredoxin peroxidase activity);GO:0098869(cellular oxidant detoxification);GO:0005623(cell);GO:0042802(identical protein binding);GO:0000302(response to reactive oxygen species);GO:0006979(response to oxidative stress);GO:0019430(removal of superoxide radicals);GO:0032872(regulation of stress-activated MAPK cascade);GO:0034101(erythrocyte homeostasis);GO:0042267(natural killer cell mediated cytotoxicity);GO:0042345(regulation of NF-kappaB import into nucleus);GO:0005739(mitochondrion);GO:0043209(myelin sheath)","04146(Peroxisome)","K13279","EC:1.11.1.15","peroxiredoxin 1 [Source:HGNC Symbol;Acc:HGNC:9352]",{"v":4.804808,"d":"4.80"},{"v":0.657658,"d":"0.66"},{"v":7.30593712841629,"d":"7.31"},{"v":2.86906933857369,"d":"2.87"},{"v":2.1243986496842E-4,"d":"0.00"},{"v":6.94836371569437E-3,"d":"0.01"},"up","yes"]
[101787,"j","chr19","+",41264417,41306991,"MSTRG.8172.10",15,2822,"MSTRG.8172","HNRNPUL1","NA","NA","NA","NA","NA",{"v":3.914534,"d":"3.91"},{"v":0.558213,"d":"0.56"},{"v":7.01261704761444,"d":"7.01"},{"v":2.80995294595011,"d":"2.81"},{"v":0.000216564843975537,"d":"0.00"},{"v":0.00707159262803287,"d":"0.01"},"up","yes"]
[53465,0,"chr14","+",24136200,24138964,"ENST00000382708",10,1136,"MSTRG.4279","PSME1","GO:0005737(cytoplasm);GO:0005515(protein binding);GO:0000502(proteasome complex);GO:0008537(proteasome activator complex);GO:0038095(Fc-epsilon receptor signaling pathway);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0000165(MAPK cascade);GO:0000209(protein polyubiquitination);GO:0002223(stimulatory C-type lectin receptor signaling pathway);GO:0002479(antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent);GO:0006521(regulation of cellular amino acid metabolic process);GO:0010972(negative regulation of G2/M transition of mitotic cell cycle);GO:0016579(protein deubiquitination);GO:0031145(anaphase-promoting complex-dependent catabolic process);GO:0031146(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process);GO:0033209(tumor necrosis factor-mediated signaling pathway);GO:0038061(NIK/NF-kappaB signaling);GO:0043161(proteasome-mediated ubiquitin-dependent protein catabolic process);GO:0043488(regulation of mRNA stability);GO:0043687(post-translational protein modification);GO:0050852(T cell receptor signaling pathway);GO:0051437(positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition);GO:0055085(transmembrane transport);GO:0060071(Wnt signaling pathway, planar cell polarity pathway);GO:0061418(regulation of transcription from RNA polymerase II promoter in response to hypoxia);GO:0090090(negative regulation of canonical Wnt signaling pathway);GO:0090263(positive regulation of canonical Wnt signaling pathway);GO:1902036(regulation of hematopoietic stem cell differentiation);GO:0051436(negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle);GO:2000045(regulation of G1/S transition of mitotic cell cycle);GO:0061133(endopeptidase activator activity);GO:0010950(positive regulation of endopeptidase activity);GO:0061136(regulation of proteasomal protein catabolic process);GO:0019884(antigen processing and presentation of exogenous antigen)","03050(Proteasome);04612(Antigen processing and presentation)","K06696","NA","proteasome activator subunit 1 [Source:HGNC Symbol;Acc:HGNC:9568]",{"v":22.881697,"d":"22.88"},{"v":3.335451,"d":"3.34"},{"v":6.86015084616743,"d":"6.86"},{"v":2.77824029981281,"d":"2.78"},{"v":0.000219568503887734,"d":"0.00"},{"v":0.00714667444464397,"d":"0.01"},"up","yes"]
[20983,0,"chr10","-",70147289,70170523,"ENST00000373242",8,5981,"MSTRG.1755","SAR1A","GO:0006810(transport);GO:0006886(intracellular protein transport);GO:0015031(protein transport);GO:0005525(GTP binding);GO:0000166(nucleotide binding);GO:0005794(Golgi apparatus);GO:0005622(intracellular);GO:0005783(endoplasmic reticulum);GO:0016192(vesicle-mediated transport);GO:0000139(Golgi membrane);GO:0005515(protein binding);GO:0070062(extracellular exosome);GO:0030127(COPII vesicle coat);GO:0090110(cargo loading into COPII-coated vesicle)","04141(Protein processing in endoplasmic reticulum);05134(Legionellosis)","K07953","EC:3.6.5.-","secretion associated Ras related GTPase 1A [Source:HGNC Symbol;Acc:HGNC:10534]",{"v":1.107828,"d":"1.11"},{"v":0.152907,"d":"0.15"},{"v":7.24510977260688,"d":"7.25"},{"v":2.85700754860841,"d":"2.86"},{"v":0.000219586520231632,"d":"0.00"},{"v":0.00714667444464397,"d":"0.01"},"up","yes"]
[164145,0,"chr6","-",30727709,30740853,"ENST00000487376",7,1583,"MSTRG.12830","FLOT1","GO:0016020(membrane);GO:0005765(lysosomal membrane);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0042470(melanosome);GO:0005901(caveola);GO:0031410(cytoplasmic vesicle);GO:0045121(membrane raft);GO:0005925(focal adhesion);GO:0005768(endosome);GO:0030027(lamellipodium);GO:0070062(extracellular exosome);GO:0001934(positive regulation of protein phosphorylation);GO:0050821(protein stabilization);GO:0022617(extracellular matrix disassembly);GO:0008180(COP9 signalosome);GO:0016323(basolateral plasma membrane);GO:0001819(positive regulation of cytokine production);GO:0005769(early endosome);GO:0016021(integral component of membrane);GO:0002020(protease binding);GO:0032092(positive regulation of protein binding);GO:0046982(protein heterodimerization activity);GO:0034976(response to endoplasmic reticulum stress);GO:0030864(cortical actin cytoskeleton);GO:0045807(positive regulation of endocytosis);GO:0032728(positive regulation of interferon-beta production);GO:1901741(positive regulation of myoblast fusion);GO:0090002(establishment of protein localization to plasma membrane);GO:0005911(cell-cell junction);GO:0001931(uropod);GO:0051260(protein homooligomerization);GO:0016600(flotillin complex);GO:0035255(ionotropic glutamate receptor binding);GO:0001765(membrane raft assembly);GO:0002090(regulation of receptor internalization);GO:0007409(axonogenesis);GO:0032226(positive regulation of synaptic transmission, dopaminergic);GO:0033227(dsRNA transport);GO:0034116(positive regulation of heterotypic cell-cell adhesion);GO:0034141(positive regulation of toll-like receptor 3 signaling pathway);GO:0035023(regulation of Rho protein signal transduction);GO:0044854(plasma membrane raft assembly);GO:0048643(positive regulation of skeletal muscle tissue development);GO:0060355(positive regulation of cell adhesion molecule production);GO:0070528(protein kinase C signaling);GO:0071360(cellular response to exogenous dsRNA);GO:0072659(protein localization to plasma membrane);GO:1901890(positive regulation of cell junction assembly);GO:1903044(protein localization to membrane raft);GO:2000049(positive regulation of cell-cell adhesion mediated by cadherin);GO:0005815(microtubule organizing center);GO:0005913(cell-cell adherens junction);GO:0034451(centriolar satellite);GO:0042383(sarcolemma);GO:0044291(cell-cell contact zone);GO:0044853(plasma membrane raft)","04910(Insulin signaling pathway)","NA","NA","flotillin 1 [Source:HGNC Symbol;Acc:HGNC:3757]",{"v":0.865353,"d":"0.87"},{"v":4.628767,"d":"4.63"},{"v":0.186951082221248,"d":"0.19"},{"v":-2.41926727220314,"d":"-2.42"},{"v":2.23232690732586E-4,"d":"0.00"},{"v":0.00725341294616815,"d":"0.01"},"down","yes"]
[54520,0,"chr14","+",39175213,39183218,"ENST00000216832",9,3576,"MSTRG.4338","PNN","GO:0003723(RNA binding);GO:0006397(mRNA processing);GO:0008380(RNA splicing);GO:0005634(nucleus);GO:0016607(nuclear speck);GO:0016020(membrane);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0005681(spliceosomal complex);GO:0030054(cell junction);GO:0005886(plasma membrane);GO:0000398(mRNA splicing, via spliceosome);GO:0007155(cell adhesion);GO:0035145(exon-exon junction complex);GO:0005198(structural molecule activity);GO:0005911(cell-cell junction);GO:0071013(catalytic step 2 spliceosome);GO:0030057(desmosome);GO:0005882(intermediate filament)","03013(RNA transport);03015(mRNA surveillance pathway)","K13114","NA","pinin, desmosome associated protein [Source:HGNC Symbol;Acc:HGNC:9162]",{"v":9.51352,"d":"9.51"},{"v":1.395488,"d":"1.40"},{"v":6.8173427503497,"d":"6.82"},{"v":2.76920951814647,"d":"2.77"},{"v":2.25379264374248E-4,"d":"0.00"},{"v":0.00731115554661904,"d":"0.01"},"up","yes"]
[22142,0,"chr10","+",89301955,89309276,"ENST00000371826",2,3489,"MSTRG.1850","IFIT2","GO:0003723(RNA binding);GO:0005737(cytoplasm);GO:0005783(endoplasmic reticulum);GO:0005515(protein binding);GO:0006915(apoptotic process);GO:0002376(immune system process);GO:0045087(innate immune response);GO:0051607(defense response to virus);GO:0035457(cellular response to interferon-alpha);GO:0005829(cytosol);GO:0009615(response to virus);GO:0043065(positive regulation of apoptotic process);GO:0032091(negative regulation of protein binding);GO:0060337(type I interferon signaling pathway);GO:0008637(apoptotic mitochondrial changes)","NA","NA","NA","interferon induced protein with tetratricopeptide repeats 2 [Source:HGNC Symbol;Acc:HGNC:5409]",{"v":2.960732,"d":"2.96"},{"v":15.183217,"d":"15.18"},{"v":0.195000308564384,"d":"0.20"},{"v":-2.3584516880204,"d":"-2.36"},{"v":0.000227015498865137,"d":"0.00"},{"v":0.00732803471064335,"d":"0.01"},"down","yes"]
[17891,0,"chr1","+",248838280,248849517,"ENST00000306562",4,2989,"MSTRG.1510","ZNF672","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0005654(nucleoplasm);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding)","NA","NA","NA","zinc finger protein 672 [Source:HGNC Symbol;Acc:HGNC:26179]",{"v":5.080348,"d":"5.08"},{"v":0.734053,"d":"0.73"},{"v":6.92095529886807,"d":"6.92"},{"v":2.79097118667969,"d":"2.79"},{"v":0.000227283074659299,"d":"0.00"},{"v":0.00732803471064335,"d":"0.01"},"up","yes"]
[87753,0,"chr17","+",74776483,74839779,"ENST00000335464",10,4745,"MSTRG.7187","TMEM104","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0003674(molecular_function);GO:0008150(biological_process);GO:0005575(cellular_component)","NA","NA","NA","transmembrane protein 104 [Source:HGNC Symbol;Acc:HGNC:25984]",{"v":3.303773,"d":"3.30"},{"v":0.478372,"d":"0.48"},{"v":6.9062842306824,"d":"6.91"},{"v":2.78790971006124,"d":"2.79"},{"v":0.000227434080202465,"d":"0.00"},{"v":0.00732803471064335,"d":"0.01"},"up","yes"]
[36067,0,"chr11","+",119206276,119308149,"ENST00000264033",16,11231,"MSTRG.2933","CBL","GO:0014068(positive regulation of phosphatidylinositol 3-kinase signaling);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0046872(metal ion binding);GO:0005829(cytosol);GO:0016740(transferase activity);GO:0016567(protein ubiquitination);GO:0005509(calcium ion binding);GO:0004871(signal transducer activity);GO:0004842(ubiquitin-protein transferase activity);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0023051(regulation of signaling);GO:0007166(cell surface receptor signaling pathway);GO:0006355(regulation of transcription, DNA-templated);GO:0042629(mast cell granule);GO:0061630(ubiquitin protein ligase activity);GO:0001784(phosphotyrosine residue binding);GO:0045296(cadherin binding);GO:0061024(membrane organization);GO:0042787(protein ubiquitination involved in ubiquitin-dependent protein catabolic process);GO:0043066(negative regulation of apoptotic process);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0048260(positive regulation of receptor-mediated endocytosis);GO:0042059(negative regulation of epidermal growth factor receptor signaling pathway);GO:0008543(fibroblast growth factor receptor signaling pathway);GO:0017124(SH3 domain binding);GO:0035635(entry of bacterium into host cell);GO:0007179(transforming growth factor beta receptor signaling pathway);GO:0045121(membrane raft);GO:0046875(ephrin receptor binding);GO:0045742(positive regulation of epidermal growth factor receptor signaling pathway);GO:0016600(flotillin complex);GO:0005154(epidermal growth factor receptor binding);GO:0019901(protein kinase binding);GO:0030971(receptor tyrosine kinase binding);GO:0036312(phosphatidylinositol 3-kinase regulatory subunit binding);GO:1990782(protein tyrosine kinase binding);GO:0000209(protein polyubiquitination);GO:0006513(protein monoubiquitination);GO:0006974(cellular response to DNA damage stimulus);GO:0007173(epidermal growth factor receptor signaling pathway);GO:0007175(negative regulation of epidermal growth factor-activated receptor activity);GO:0008584(male gonad development);GO:0010332(response to gamma radiation);GO:0014823(response to activity);GO:0033574(response to testosterone);GO:0036120(cellular response to platelet-derived growth factor stimulus);GO:0042594(response to starvation);GO:0043303(mast cell degranulation);GO:0045471(response to ethanol);GO:0046677(response to antibiotic);GO:0070997(neuron death);GO:0071364(cellular response to epidermal growth factor stimulus);GO:0090650(cellular response to oxygen-glucose deprivation);GO:1901215(negative regulation of neuron death);GO:1990090(cellular response to nerve growth factor stimulus);GO:0005925(focal adhesion);GO:0030424(axon);GO:0030426(growth cone);GO:0048471(perinuclear region of cytoplasm)","04120(Ubiquitin mediated proteolysis);04012(ErbB signaling pathway);04144(Endocytosis);04660(T cell receptor signaling pathway);04910(Insulin signaling pathway);05200(Pathways in cancer);05205(Proteoglycans in cancer);05220(Chronic myeloid leukemia);05100(Bacterial invasion of epithelial cells)","K04707","EC:2.3.2.27","Cbl proto-oncogene [Source:HGNC Symbol;Acc:HGNC:1541]",{"v":14.65682,"d":"14.66"},{"v":2.1767,"d":"2.18"},{"v":6.73350484678642,"d":"6.73"},{"v":2.75135763542894,"d":"2.75"},{"v":2.27663015147397E-4,"d":"0.00"},{"v":0.00732803471064335,"d":"0.01"},"up","yes"]
[198317,0,"chrX","-",73820656,73852753,"ENST00000429829",6,19275,"MSTRG.15366","XIST","NA","NA","NA","NA","X inactive specific transcript (non-protein coding) [Source:HGNC Symbol;Acc:HGNC:12810]",{"v":13.053886,"d":"13.05"},{"v":1.940722,"d":"1.94"},{"v":6.72630392194245,"d":"6.73"},{"v":2.74981396720425,"d":"2.75"},{"v":0.000227974758170105,"d":"0.00"},{"v":0.00732803471064335,"d":"0.01"},"up","yes"]
[29652,0,"chr11","-",60172014,60183104,"ENST00000528851",6,1806,"MSTRG.2426","MS4A6A","GO:0016020(membrane);GO:0016021(integral component of membrane)","NA","NA","NA","membrane spanning 4-domains A6A [Source:HGNC Symbol;Acc:HGNC:13375]",{"v":5.564956,"d":"5.56"},{"v":28.493536,"d":"28.49"},{"v":0.195305910786222,"d":"0.20"},{"v":-2.35619248292364,"d":"-2.36"},{"v":0.000228247193951028,"d":"0.00"},{"v":0.00732803471064335,"d":"0.01"},"down","yes"]
[34852,0,"chr11","+",108287392,108366034,"ENST00000524792",37,5912,"MSTRG.2836","ATM","GO:0004674(protein serine/threonine kinase activity);GO:0006468(protein phosphorylation);GO:0005634(nucleus);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0006974(cellular response to DNA damage stimulus);GO:0007049(cell cycle);GO:0031410(cytoplasmic vesicle);GO:0036092(phosphatidylinositol-3-phosphate biosynthetic process);GO:0005730(nucleolus);GO:0006977(DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest);GO:0005654(nucleoplasm);GO:0000784(nuclear chromosome, telomeric region);GO:0043065(positive regulation of apoptotic process);GO:0047485(protein N-terminus binding);GO:0007165(signal transduction);GO:0042981(regulation of apoptotic process);GO:1901796(regulation of signal transduction by p53 class mediator);GO:0006260(DNA replication);GO:0016303(1-phosphatidylinositol-3-kinase activity);GO:0046777(protein autophosphorylation);GO:0032212(positive regulation of telomere maintenance via telomerase);GO:0090399(replicative senescence);GO:0000781(chromosome, telomeric region);GO:0006975(DNA damage induced protein phosphorylation);GO:0071044(histone mRNA catabolic process);GO:0018105(peptidyl-serine phosphorylation);GO:0000731(DNA synthesis involved in DNA repair);GO:0000732(strand displacement);GO:0007131(reciprocal meiotic recombination);GO:1900034(regulation of cellular response to heat);GO:0007094(mitotic spindle assembly checkpoint);GO:1990391(DNA repair complex);GO:0006281(DNA repair);GO:0000729(DNA double-strand break processing);GO:0006303(double-strand break repair via nonhomologous end joining);GO:1904354(negative regulation of telomere capping);GO:0030889(negative regulation of B cell proliferation);GO:0010212(response to ionizing radiation);GO:0032210(regulation of telomere maintenance via telomerase);GO:0007050(cell cycle arrest);GO:0071480(cellular response to gamma radiation);GO:0010506(regulation of autophagy);GO:0002331(pre-B cell allelic exclusion);GO:1904358(positive regulation of telomere maintenance via telomere lengthening);GO:0043517(positive regulation of DNA damage response, signal transduction by p53 class mediator);GO:0032403(protein complex binding);GO:0004677(DNA-dependent protein kinase activity);GO:0046983(protein dimerization activity);GO:0036289(peptidyl-serine autophosphorylation);GO:0071481(cellular response to X-ray);GO:0071500(cellular response to nitrosative stress);GO:0072434(signal transduction involved in mitotic G2 DNA damage checkpoint);GO:0097694(establishment of RNA localization to telomere);GO:0097695(establishment of macromolecular complex localization to telomere);GO:1904262(negative regulation of TORC1 signaling);GO:1904884(positive regulation of telomerase catalytic core complex assembly);GO:0004672(protein kinase activity);GO:0000077(DNA damage checkpoint);GO:0000724(double-strand break repair via homologous recombination);GO:0001541(ovarian follicle development);GO:0001666(response to hypoxia);GO:0001756(somitogenesis);GO:0002376(immune system process);GO:0002377(immunoglobulin production);GO:0006915(apoptotic process);GO:0007140(male meiotic nuclear division);GO:0007143(female meiotic nuclear division);GO:0007292(female gamete generation);GO:0007420(brain development);GO:0007507(heart development);GO:0008340(determination of adult lifespan);GO:0008585(female gonad development);GO:0008630(intrinsic apoptotic signaling pathway in response to DNA damage);GO:0009791(post-embryonic development);GO:0033129(positive regulation of histone phosphorylation);GO:0033151(V(D)J recombination);GO:0035264(multicellular organism growth);GO:0042159(lipoprotein catabolic process);GO:0043525(positive regulation of neuron apoptotic process);GO:0045141(meiotic telomere clustering);GO:0048538(thymus development);GO:0048599(oocyte development);GO:0051402(neuron apoptotic process);GO:0051726(regulation of cell cycle);GO:0070192(chromosome organization involved in meiotic cell cycle);GO:1901216(positive regulation of neuron death);GO:1903626(positive regulation of DNA catabolic process);GO:1903978(regulation of microglial cell activation);GO:1905843(regulation of cellular response to gamma radiation);GO:2001022(positive regulation of response to DNA damage stimulus);GO:0005737(cytoplasm);GO:0005819(spindle)","03440(Homologous recombination);04064(NF-kappa B signaling pathway);04068(FoxO signaling pathway);04110(Cell cycle);04210(Apoptosis);04115(p53 signaling pathway);04218(Cellular senescence);05202(Transcriptional misregulation in cancers);05206(MicroRNAs in cancer);05166(HTLV-I infection);05165(Human papillomavirus infection);01524(Platinum drug resistance)","NA","NA","ATM serine/threonine kinase [Source:HGNC Symbol;Acc:HGNC:795]",{"v":5.919563,"d":"5.92"},{"v":0.87011,"d":"0.87"},{"v":6.80323522313271,"d":"6.80"},{"v":2.76622097142358,"d":"2.77"},{"v":2.28771097613545E-4,"d":"0.00"},{"v":0.00732803471064335,"d":"0.01"},"up","yes"]
[18820,0,"chr10","-",16590620,16817454,"ENST00000602389",8,3639,"MSTRG.1593","RSU1","GO:0005515(protein binding);GO:0005925(focal adhesion);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0043547(positive regulation of GTPase activity);GO:0007165(signal transduction);GO:0010811(positive regulation of cell-substrate adhesion)","NA","NA","NA","Ras suppressor protein 1 [Source:HGNC Symbol;Acc:HGNC:10464]",{"v":0.817404,"d":"0.82"},{"v":4.248633,"d":"4.25"},{"v":0.192392235337813,"d":"0.19"},{"v":-2.37787751961348,"d":"-2.38"},{"v":0.000228862212006145,"d":"0.00"},{"v":0.00732803471064335,"d":"0.01"},"down","yes"]
[35620,0,"chr11","+",117986348,118001479,"ENST00000227752",7,3695,"MSTRG.2870","IL10RA","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005515(protein binding);GO:0019221(cytokine-mediated signaling pathway);GO:0007165(signal transduction);GO:0005886(plasma membrane);GO:0004920(interleukin-10 receptor activity);GO:0004871(signal transducer activity);GO:0004872(receptor activity);GO:0019969(interleukin-10 binding);GO:0032496(response to lipopolysaccharide);GO:0050807(regulation of synapse organization)","04630(Jak-STAT signaling pathway);04060(Cytokine-cytokine receptor interaction);05152(Tuberculosis);05169(Epstein-Barr virus infection);05145(Toxoplasmosis)","K05134","NA","interleukin 10 receptor subunit alpha [Source:HGNC Symbol;Acc:HGNC:5964]",{"v":1.976192,"d":"1.98"},{"v":10.138362,"d":"10.14"},{"v":0.194922217218127,"d":"0.19"},{"v":-2.3590295566586,"d":"-2.36"},{"v":2.30105056702082E-4,"d":"0.00"},{"v":0.00735592707919354,"d":"0.01"},"down","yes"]
[9809,0,"chr1","-",119911553,120069626,"ENST00000256646",34,11389,"MSTRG.839","NOTCH2","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005654(nucleoplasm);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0005509(calcium ion binding);GO:0005886(plasma membrane);GO:0007275(multicellular organism development);GO:0030522(intracellular receptor signaling pathway);GO:0030154(cell differentiation);GO:0006915(apoptotic process);GO:0007399(nervous system development);GO:0007219(Notch signaling pathway);GO:0004872(receptor activity);GO:0005576(extracellular region);GO:0005887(integral component of plasma membrane);GO:0005515(protein binding);GO:0050793(regulation of developmental process);GO:0005789(endoplasmic reticulum membrane);GO:0008285(negative regulation of cell proliferation);GO:0007050(cell cycle arrest);GO:0043066(negative regulation of apoptotic process);GO:0009986(cell surface);GO:0006367(transcription initiation from RNA polymerase II promoter);GO:0000139(Golgi membrane);GO:0001709(cell fate determination);GO:0002315(marginal zone B cell differentiation);GO:0030097(hemopoiesis);GO:0009887(animal organ morphogenesis);GO:0043235(receptor complex);GO:0016049(cell growth);GO:0046579(positive regulation of Ras protein signal transduction);GO:0019827(stem cell population maintenance);GO:0003184(pulmonary valve morphogenesis);GO:0046849(bone remodeling);GO:0061314(Notch signaling involved in heart development);GO:0060413(atrial septum morphogenesis);GO:0038049(transcription factor activity, ligand-activated RNA polymerase II transcription factor binding)","04330(Notch signaling pathway);04658(Th1 and Th2 cell differentiation);04919(Thyroid hormone signaling pathway);05200(Pathways in cancer);05206(MicroRNAs in cancer);05224(Breast cancer);05165(Human papillomavirus infection);01522(Endocrine resistance)","K20994","NA","notch 2 [Source:HGNC Symbol;Acc:HGNC:7882]",{"v":31.948019,"d":"31.95"},{"v":4.758564,"d":"4.76"},{"v":6.71379411940241,"d":"6.71"},{"v":2.74712829701889,"d":"2.75"},{"v":0.000230793047531552,"d":"0.00"},{"v":0.00736602068476508,"d":"0.01"},"up","yes"]
[5719,0,"chr1","-",46607725,46616465,"ENST00000371940",3,5725,"MSTRG.540","MOB3C","GO:0046872(metal ion binding);GO:0005515(protein binding)","NA","NA","NA","MOB kinase activator 3C [Source:HGNC Symbol;Acc:HGNC:29800]",{"v":1.024247,"d":"1.02"},{"v":0.142172,"d":"0.14"},{"v":7.20428073038292,"d":"7.20"},{"v":2.84885440007264,"d":"2.85"},{"v":2.31444372735288E-4,"d":"0.00"},{"v":0.00737491344232831,"d":"0.01"},"up","yes"]
[64410,0,"chr15","+",73135985,73305198,"ENST00000560328",24,5895,"ENSG00000067141","NEO1","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005794(Golgi apparatus);GO:0005654(nucleoplasm);GO:0007155(cell adhesion);GO:0005887(integral component of plasma membrane);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0007399(nervous system development);GO:0007411(axon guidance);GO:0055072(iron ion homeostasis);GO:0004872(receptor activity);GO:0030513(positive regulation of BMP signaling pathway);GO:0039706(co-receptor binding);GO:0098797(plasma membrane protein complex)","04514(Cell adhesion molecules (CAMs))","NA","NA","neogenin 1 [Source:HGNC Symbol;Acc:HGNC:7754]",{"v":0.966512,"d":"0.97"},{"v":0.134001,"d":"0.13"},{"v":7.21272229311722,"d":"7.21"},{"v":2.85054387770763,"d":"2.85"},{"v":0.000232752571619556,"d":"0.00"},{"v":0.00740467505981959,"d":"0.01"},"up","yes"]
[88715,0,"chr17","-",78113076,78128772,"ENST00000593044",19,3070,"MSTRG.7280","TMC6","GO:0006810(transport);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005794(Golgi apparatus);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0006811(ion transport);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0008150(biological_process);GO:0070062(extracellular exosome);GO:0043312(neutrophil degranulation);GO:0035579(specific granule membrane);GO:0070821(tertiary granule membrane);GO:0031965(nuclear membrane)","NA","NA","NA","transmembrane channel like 6 [Source:HGNC Symbol;Acc:HGNC:18021]",{"v":2.955922,"d":"2.96"},{"v":0.423315,"d":"0.42"},{"v":6.98279531790747,"d":"6.98"},{"v":2.80380468456983,"d":"2.80"},{"v":2.35471069749597E-4,"d":"0.00"},{"v":0.0074791356793018,"d":"0.01"},"up","yes"]
[173983,"j","chr7","+",50304054,50405097,"MSTRG.13644.2",8,6350,"MSTRG.13644","IKZF1","NA","NA","NA","NA","NA",{"v":2.469472,"d":"2.47"},{"v":0.358487,"d":"0.36"},{"v":6.88859568129388,"d":"6.89"},{"v":2.78420990308471,"d":"2.78"},{"v":0.000236200142345078,"d":"0.00"},{"v":0.00749026989859681,"d":"0.01"},"up","yes"]
[191180,0,"chr9","+",77177445,77421541,"ENST00000360280",72,15320,"ENSG00000197969","VPS13A","GO:0006810(transport);GO:0015031(protein transport);GO:0005829(cytosol);GO:0005515(protein binding);GO:0005622(intracellular);GO:0006895(Golgi to endosome transport);GO:0008104(protein localization);GO:0006914(autophagy);GO:0007399(nervous system development);GO:0007626(locomotory behavior);GO:0035176(social behavior);GO:0031045(dense core granule)","NA","NA","NA","vacuolar protein sorting 13 homolog A [Source:HGNC Symbol;Acc:HGNC:1908]",{"v":1.823735,"d":"1.82"},{"v":0.269697,"d":"0.27"},{"v":6.7621627233525,"d":"6.76"},{"v":2.75748473337844,"d":"2.76"},{"v":2.40005619884747E-4,"d":"0.00"},{"v":0.007598769930047,"d":"0.01"},"up","yes"]
[198735,0,"chrX","+",96685017,97469765,"ENST00000373054",28,3376,"ENSG00000147202","DIAPH2","GO:0005737(cytoplasm);GO:0043231(intracellular membrane-bounded organelle);GO:0005783(endoplasmic reticulum);GO:0005730(nucleolus);GO:0003779(actin binding);GO:0007015(actin filament organization);GO:0005829(cytosol);GO:0030036(actin cytoskeleton organization);GO:0007275(multicellular organism development);GO:0030154(cell differentiation);GO:0016043(cellular component organization);GO:0017048(Rho GTPase binding);GO:0005768(endosome);GO:0005769(early endosome);GO:0007292(female gamete generation);GO:0048477(oogenesis);GO:0005102(receptor binding);GO:0000910(cytokinesis)","04810(Regulation of actin cytoskeleton)","NA","NA","diaphanous related formin 2 [Source:HGNC Symbol;Acc:HGNC:2877]",{"v":0.311592,"d":"0.31"},{"v":1.666921,"d":"1.67"},{"v":0.186926674989397,"d":"0.19"},{"v":-2.41945563426386,"d":"-2.42"},{"v":0.000241442127180895,"d":"0.00"},{"v":0.00762071759757285,"d":"0.01"},"down","yes"]
[29559,0,"chr11","+",59148245,59155036,"ENST00000531147",2,3996,"ENSG00000166801","FAM111A","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0001650(fibrillar center);GO:0006260(DNA replication);GO:0051607(defense response to virus);GO:0005515(protein binding);GO:0045071(negative regulation of viral genome replication);GO:0016032(viral process);GO:0000785(chromatin)","NA","NA","NA","family with sequence similarity 111 member A [Source:HGNC Symbol;Acc:HGNC:24725]",{"v":2.54369,"d":"2.54"},{"v":0.366753,"d":"0.37"},{"v":6.93570332076357,"d":"6.94"},{"v":2.79404218765759,"d":"2.79"},{"v":2.4146906881333E-4,"d":"0.00"},{"v":0.00762071759757285,"d":"0.01"},"up","yes"]
[18385,0,"chr10","+",8054806,8074890,"ENST00000346208",6,2654,"MSTRG.1545","GATA3","GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0005634(nucleus);GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0005654(nucleoplasm);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0043565(sequence-specific DNA binding);GO:0005515(protein binding);GO:0007165(signal transduction);GO:0003713(transcription coactivator activity);GO:0045893(positive regulation of transcription, DNA-templated);GO:0002376(immune system process);GO:0045087(innate immune response);GO:0003682(chromatin binding);GO:0045582(positive regulation of T cell differentiation);GO:0000976(transcription regulatory region sequence-specific DNA binding);GO:0008285(negative regulation of cell proliferation);GO:0016579(protein deubiquitination);GO:1902036(regulation of hematopoietic stem cell differentiation);GO:0008584(male gonad development);GO:0009615(response to virus);GO:0005667(transcription factor complex);GO:0050728(negative regulation of inflammatory response);GO:0071356(cellular response to tumor necrosis factor);GO:0000977(RNA polymerase II regulatory region sequence-specific DNA binding);GO:0001228(transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding);GO:0032753(positive regulation of interleukin-4 production);GO:2000667(positive regulation of interleukin-13 secretion);GO:0044212(transcription regulatory region DNA binding);GO:0045786(negative regulation of cell cycle);GO:0045892(negative regulation of transcription, DNA-templated);GO:0000790(nuclear chromatin);GO:0006366(transcription from RNA polymerase II promoter);GO:0045599(negative regulation of fat cell differentiation);GO:0014065(phosphatidylinositol 3-kinase signaling);GO:0050852(T cell receptor signaling pathway);GO:0009653(anatomical structure morphogenesis);GO:2000352(negative regulation of endothelial cell apoptotic process);GO:0001709(cell fate determination);GO:0001046(core promoter sequence-specific DNA binding);GO:0070888(E-box binding);GO:0006952(defense response);GO:0043627(response to estrogen);GO:0010595(positive regulation of endothelial cell migration);GO:0051897(positive regulation of protein kinase B signaling);GO:0001078(transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0007596(blood coagulation);GO:0000987(core promoter proximal region sequence-specific DNA binding);GO:0001823(mesonephros development);GO:0060037(pharyngeal system development);GO:0008134(transcription factor binding);GO:0001822(kidney development);GO:0048485(sympathetic nervous system development);GO:2000611(positive regulation of thyroid hormone generation);GO:0071837(HMG box domain binding);GO:0042421(norepinephrine biosynthetic process);GO:2000146(negative regulation of cell motility);GO:0001085(RNA polymerase II transcription factor binding);GO:0035457(cellular response to interferon-alpha);GO:0071353(cellular response to interleukin-4);GO:0060231(mesenchymal to epithelial transition);GO:0031929(TOR signaling);GO:0000979(RNA polymerase II core promoter sequence-specific DNA binding);GO:0001071(nucleic acid binding transcription factor activity);GO:0001077(transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0001158(enhancer sequence-specific DNA binding);GO:0005134(interleukin-2 receptor binding);GO:0046983(protein dimerization activity);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0000902(cell morphogenesis);GO:0001701(in utero embryonic development);GO:0001764(neuron migration);GO:0001775(cell activation);GO:0001806(type IV hypersensitivity);GO:0001819(positive regulation of cytokine production);GO:0002088(lens development in camera-type eye);GO:0002572(pro-T cell differentiation);GO:0003180(aortic valve morphogenesis);GO:0003215(cardiac right ventricle morphogenesis);GO:0003281(ventricular septum development);GO:0006338(chromatin remodeling);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0006959(humoral immune response);GO:0007399(nervous system development);GO:0007411(axon guidance);GO:0009791(post-embryonic development);GO:0009967(positive regulation of signal transduction);GO:0010332(response to gamma radiation);GO:0010628(positive regulation of gene expression);GO:0010629(negative regulation of gene expression);GO:0010975(regulation of neuron projection development);GO:0030182(neuron differentiation);GO:0030217(T cell differentiation);GO:0030218(erythrocyte differentiation);GO:0032689(negative regulation of interferon-gamma production);GO:0032703(negative regulation of interleukin-2 production);GO:0032736(positive regulation of interleukin-13 production);GO:0032754(positive regulation of interleukin-5 production);GO:0033077(T cell differentiation in thymus);GO:0033600(negative regulation of mammary gland epithelial cell proliferation);GO:0035162(embryonic hemopoiesis);GO:0035799(ureter maturation);GO:0035898(parathyroid hormone secretion);GO:0042035(regulation of cytokine biosynthetic process);GO:0042472(inner ear morphogenesis);GO:0042493(response to drug);GO:0043370(regulation of CD4-positive, alpha-beta T cell differentiation);GO:0043523(regulation of neuron apoptotic process);GO:0043583(ear development);GO:0045061(thymic T cell selection);GO:0045064(T-helper 2 cell differentiation);GO:0045471(response to ethanol);GO:0045597(positive regulation of cell differentiation);GO:0048469(cell maturation);GO:0048538(thymus development);GO:0048568(embryonic organ development);GO:0048589(developmental growth);GO:0048646(anatomical structure formation involved in morphogenesis);GO:0048872(homeostasis of number of cells);GO:0051569(regulation of histone H3-K4 methylation);GO:0060017(parathyroid gland development);GO:0060065(uterus development);GO:0060374(mast cell differentiation);GO:0060676(ureteric bud formation);GO:0061085(regulation of histone H3-K27 methylation);GO:0061290(canonical Wnt signaling pathway involved in metanephric kidney development);GO:0071345(cellular response to cytokine stimulus);GO:0071442(positive regulation of histone H3-K14 acetylation);GO:0071599(otic vesicle development);GO:0071773(cellular response to BMP stimulus);GO:0072001(renal system development);GO:0072107(positive regulation of ureteric bud formation);GO:0072178(nephric duct morphogenesis);GO:0072179(nephric duct formation);GO:0072182(regulation of nephron tubule epithelial cell differentiation);GO:0072602(interleukin-4 secretion);GO:0072643(interferon-gamma secretion);GO:0072676(lymphocyte migration);GO:0090102(cochlea development);GO:1901536(negative regulation of DNA demethylation);GO:2000114(regulation of establishment of cell polarity);GO:2000553(positive regulation of T-helper 2 cell cytokine production);GO:2000607(negative regulation of cell proliferation involved in mesonephros development);GO:2000617(positive regulation of histone H3-K9 acetylation);GO:2000664(positive regulation of interleukin-5 secretion);GO:2000679(positive regulation of transcription regulatory region DNA binding);GO:2000683(regulation of cellular response to X-ray);GO:2000703(negative regulation of fibroblast growth factor receptor signaling pathway involved in ureteric bud formation);GO:2000734(negative regulation of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation)","04658(Th1 and Th2 cell differentiation);04659(Th17 cell differentiation);05321(Inflammatiory bowel disease (IBD))","K17895","NA","GATA binding protein 3 [Source:HGNC Symbol;Acc:HGNC:4172]",{"v":2.252792,"d":"2.25"},{"v":0.315683,"d":"0.32"},{"v":7.13624743809454,"d":"7.14"},{"v":2.83516563929452,"d":"2.84"},{"v":0.000242097072897957,"d":"0.00"},{"v":0.00762837082564456,"d":"0.01"},"up","yes"]
[39167,0,"chr12","+",14365632,14502935,"ENST00000261168",15,8878,"MSTRG.3227","ATF7IP","GO:0005634(nucleus);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0005515(protein binding);GO:0016604(nuclear body);GO:0045893(positive regulation of transcription, DNA-templated);GO:0016032(viral process);GO:0045892(negative regulation of transcription, DNA-templated);GO:0006306(DNA methylation);GO:0045898(regulation of RNA polymerase II transcriptional preinitiation complex assembly);GO:0003714(transcription corepressor activity);GO:0016887(ATPase activity);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0005667(transcription factor complex)","NA","NA","NA","activating transcription factor 7 interacting protein [Source:HGNC Symbol;Acc:HGNC:20092]",{"v":10.274049,"d":"10.27"},{"v":1.536498,"d":"1.54"},{"v":6.68666604186924,"d":"6.69"},{"v":2.74128706531188,"d":"2.74"},{"v":0.000242596436495762,"d":"0.00"},{"v":0.00763195275894774,"d":"0.01"},"up","yes"]
[160790,0,"chr5","+",163503114,163519336,"ENST00000280969",7,2226,"MSTRG.12524","MAT2B","GO:0005634(nucleus);GO:0006730(one-carbon metabolic process);GO:0050790(regulation of catalytic activity);GO:0005515(protein binding);GO:0006556(S-adenosylmethionine biosynthetic process);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0005622(intracellular);GO:0019899(enzyme binding);GO:0032259(methylation);GO:0048269(methionine adenosyltransferase complex);GO:0048270(methionine adenosyltransferase regulator activity);GO:0005739(mitochondrion)","00270(Cysteine and methionine metabolism)","K00789","EC:2.5.1.6","methionine adenosyltransferase 2B [Source:HGNC Symbol;Acc:HGNC:6905]",{"v":2.852915,"d":"2.85"},{"v":14.536482,"d":"14.54"},{"v":0.196258971049529,"d":"0.20"},{"v":-2.34916949340355,"d":"-2.35"},{"v":2.43692068219902E-4,"d":"0.00"},{"v":7.65425181894512E-3,"d":"0.01"},"down","yes"]
[8077,0,"chr1","-",93151858,93180516,"ENST00000370290",5,3847,"MSTRG.714","TMED5","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0015031(protein transport);GO:0005794(Golgi apparatus);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005515(protein binding);GO:0090161(Golgi ribbon formation);GO:0005793(endoplasmic reticulum-Golgi intermediate compartment);GO:0033116(endoplasmic reticulum-Golgi intermediate compartment membrane);GO:0070971(endoplasmic reticulum exit site);GO:0005801(cis-Golgi network)","NA","NA","NA","transmembrane p24 trafficking protein 5 [Source:HGNC Symbol;Acc:HGNC:24251]",{"v":0.197012,"d":"0.20"},{"v":1.078472,"d":"1.08"},{"v":0.182676972605687,"d":"0.18"},{"v":-2.45263330876742,"d":"-2.45"},{"v":2.46774875955826E-4,"d":"0.00"},{"v":0.00772772539259423,"d":"0.01"},"down","yes"]
[67265,0,"chr16","-",85801,138512,"ENST00000399953",12,2784,"MSTRG.5474","NPRL3","GO:0016020(membrane);GO:0005765(lysosomal membrane);GO:0043547(positive regulation of GTPase activity);GO:0005096(GTPase activator activity);GO:0005764(lysosome);GO:0003674(molecular_function);GO:0008150(biological_process);GO:0005575(cellular_component);GO:2000785(regulation of autophagosome assembly);GO:0032007(negative regulation of TOR signaling);GO:0034198(cellular response to amino acid starvation);GO:1990130(GATOR1 complex);GO:0038202(TORC1 signaling);GO:0003281(ventricular septum development);GO:0035909(aorta morphogenesis);GO:0048738(cardiac muscle tissue development);GO:0060021(palate development)","04150(mTOR signaling pathway)","K20406","NA","NPR3 like, GATOR1 complex subunit [Source:HGNC Symbol;Acc:HGNC:14124]",{"v":12.576571,"d":"12.58"},{"v":1.871518,"d":"1.87"},{"v":6.71998399160468,"d":"6.72"},{"v":2.74845779620938,"d":"2.75"},{"v":0.000247491433257328,"d":"0.00"},{"v":0.00772772539259423,"d":"0.01"},"up","yes"]
[187961,"j","chr8","-",143574785,143597429,"MSTRG.14619.2",18,3759,"MSTRG.14619","NAPRT","NA","NA","NA","NA","NA",{"v":39.141335,"d":"39.14"},{"v":5.880077,"d":"5.88"},{"v":6.65660245605627,"d":"6.66"},{"v":2.73478601055711,"d":"2.73"},{"v":0.000247567001680716,"d":"0.00"},{"v":0.00772772539259423,"d":"0.01"},"up","yes"]
[158071,0,"chr5","+",131264009,131394687,"ENST00000395246",5,3485,"MSTRG.12279","CDC42SE2","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005886(plasma membrane);GO:0005856(cytoskeleton);GO:0042995(cell projection);GO:0005515(protein binding);GO:0070062(extracellular exosome);GO:0001891(phagocytic cup);GO:0008360(regulation of cell shape);GO:0006909(phagocytosis);GO:0009966(regulation of signal transduction);GO:0005198(structural molecule activity)","NA","NA","NA","CDC42 small effector 2 [Source:HGNC Symbol;Acc:HGNC:18547]",{"v":4.122604,"d":"4.12"},{"v":0.603547,"d":"0.60"},{"v":6.83062628096901,"d":"6.83"},{"v":2.77201786124241,"d":"2.77"},{"v":2.47593384824375E-4,"d":"0.00"},{"v":0.00772772539259423,"d":"0.01"},"up","yes"]
[111028,0,"chr2","-",73073382,73112783,"ENST00000486777",6,6120,"ENSG00000135631","RAB11FIP5","GO:0006810(transport);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0015031(protein transport);GO:0043231(intracellular membrane-bounded organelle);GO:0005794(Golgi apparatus);GO:0005739(mitochondrion);GO:0005515(protein binding);GO:0000139(Golgi membrane);GO:0005815(microtubule organizing center);GO:0005741(mitochondrial outer membrane);GO:0031410(cytoplasmic vesicle);GO:0017137(Rab GTPase binding);GO:0031966(mitochondrial membrane);GO:0005768(endosome);GO:0005769(early endosome);GO:0031901(early endosome membrane);GO:0055037(recycling endosome);GO:0055038(recycling endosome membrane);GO:2000008(regulation of protein localization to cell surface);GO:0030141(secretory granule);GO:0030658(transport vesicle membrane);GO:0070164(negative regulation of adiponectin secretion);GO:0043015(gamma-tubulin binding);GO:0071468(cellular response to acidic pH);GO:0045055(regulated exocytosis);GO:0035773(insulin secretion involved in cellular response to glucose stimulus)","04144(Endocytosis)","K12484","NA","RAB11 family interacting protein 5 [Source:HGNC Symbol;Acc:HGNC:24845]",{"v":0.173415,"d":"0.17"},{"v":0.929049,"d":"0.93"},{"v":0.186658615422868,"d":"0.19"},{"v":-2.42152599561688,"d":"-2.42"},{"v":0.000248255618260124,"d":"0.00"},{"v":0.00773619240020683,"d":"0.01"},"down","yes"]
[57012,0,"chr14","+",75661278,75955078,"ENST00000298832",32,4683,"MSTRG.4564","TTLL5","GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0006464(cellular protein modification process);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0006351(transcription, DNA-templated);GO:0005856(cytoskeleton);GO:0042995(cell projection);GO:0016874(ligase activity);GO:0005874(microtubule);GO:0005813(centrosome);GO:0005929(cilium);GO:0070740(tubulin-glutamic acid ligase activity);GO:0018095(protein polyglutamylation);GO:0060041(retina development in camera-type eye);GO:0007283(spermatogenesis);GO:0007288(sperm axoneme assembly);GO:0009566(fertilization);GO:0030317(flagellated sperm motility)","NA","NA","NA","tubulin tyrosine ligase like 5 [Source:HGNC Symbol;Acc:HGNC:19963]",{"v":1.221973,"d":"1.22"},{"v":0.170869,"d":"0.17"},{"v":7.15151958517929,"d":"7.15"},{"v":2.83824982441851,"d":"2.84"},{"v":0.000248923610577181,"d":"0.00"},{"v":0.00774124697429666,"d":"0.01"},"up","yes"]
[201451,0,"chrX","-",155258241,155264589,"ENST00000369454",2,3505,"ENSG00000155961","RAB39B","GO:0006810(transport);GO:0016020(membrane);GO:0015031(protein transport);GO:0005525(GTP binding);GO:0000166(nucleotide binding);GO:0003924(GTPase activity);GO:0005794(Golgi apparatus);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0006914(autophagy);GO:0030659(cytoplasmic vesicle membrane);GO:0031410(cytoplasmic vesicle);GO:0016192(vesicle-mediated transport);GO:0043005(neuron projection);GO:0031489(myosin V binding);GO:0031982(vesicle);GO:0010506(regulation of autophagy);GO:0050808(synapse organization);GO:0005622(intracellular)","NA","NA","NA","RAB39B, member RAS oncogene family [Source:HGNC Symbol;Acc:HGNC:16499]",{"v":0.332516,"d":"0.33"},{"v":1.779442,"d":"1.78"},{"v":0.186865320701658,"d":"0.19"},{"v":-2.41992924273313,"d":"-2.42"},{"v":0.000249200238661157,"d":"0.00"},{"v":0.00774124697429666,"d":"0.01"},"down","yes"]
[135684,0,"chr3","+",47381020,47413441,"ENST00000265562",25,5244,"MSTRG.10888","PTPN23","GO:0006810(transport);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0015031(protein transport);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0016787(hydrolase activity);GO:0004725(protein tyrosine phosphatase activity);GO:0016791(phosphatase activity);GO:0006470(protein dephosphorylation);GO:0016311(dephosphorylation);GO:0035335(peptidyl-tyrosine dephosphorylation);GO:0004721(phosphoprotein phosphatase activity);GO:0005856(cytoskeleton);GO:0042995(cell projection);GO:0005515(protein binding);GO:0016604(nuclear body);GO:0031410(cytoplasmic vesicle);GO:0060271(cilium assembly);GO:0030334(regulation of cell migration);GO:0005768(endosome);GO:0005929(cilium);GO:0070062(extracellular exosome);GO:0019901(protein kinase binding);GO:0030030(cell projection organization);GO:0036064(ciliary basal body);GO:0005769(early endosome);GO:0043162(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway);GO:0010633(negative regulation of epithelial cell migration);GO:2000643(positive regulation of early endosome to late endosome transport);GO:0032456(endocytic recycling);GO:0045022(early endosome to late endosome transport);GO:0061357(positive regulation of Wnt protein secretion);GO:1903387(positive regulation of homophilic cell adhesion);GO:1903393(positive regulation of adherens junction organization)","NA","NA","NA","protein tyrosine phosphatase, non-receptor type 23 [Source:HGNC Symbol;Acc:HGNC:14406]",{"v":3.01105,"d":"3.01"},{"v":0.442956,"d":"0.44"},{"v":6.79762775535268,"d":"6.80"},{"v":2.76503136067177,"d":"2.77"},{"v":2.50934912860175E-4,"d":"0.00"},{"v":0.00777507785162967,"d":"0.01"},"up","yes"]
[63669,0,"chr15","-",65446619,65517699,"ENST00000300141",20,3139,"ENSG00000074603","DPP8","GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0016787(hydrolase activity);GO:0008233(peptidase activity);GO:0006508(proteolysis);GO:0006955(immune response);GO:0008236(serine-type peptidase activity);GO:0004177(aminopeptidase activity);GO:0008239(dipeptidyl-peptidase activity)","NA","NA","NA","dipeptidyl peptidase 8 [Source:HGNC Symbol;Acc:HGNC:16490]",{"v":5.127683,"d":"5.13"},{"v":0.754048,"d":"0.75"},{"v":6.80020767908674,"d":"6.80"},{"v":2.76557880710023,"d":"2.77"},{"v":0.000251075133777611,"d":"0.00"},{"v":0.00777507785162967,"d":"0.01"},"up","yes"]
[146722,0,"chr4","-",38772239,38782958,"ENST00000308973",4,3958,"ENSG00000174123","TLR10","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0007165(signal transduction);GO:0006955(immune response);GO:0004888(transmembrane signaling receptor activity);GO:0002376(immune system process);GO:0002755(MyD88-dependent toll-like receptor signaling pathway);GO:0034166(toll-like receptor 10 signaling pathway);GO:0045087(innate immune response);GO:0050707(regulation of cytokine secretion);GO:0050729(positive regulation of inflammatory response);GO:0006954(inflammatory response);GO:0005886(plasma membrane);GO:0005887(integral component of plasma membrane);GO:0002224(toll-like receptor signaling pathway)","NA","NA","NA","toll like receptor 10 [Source:HGNC Symbol;Acc:HGNC:15634]",{"v":0.318614,"d":"0.32"},{"v":1.673455,"d":"1.67"},{"v":0.190392929597748,"d":"0.19"},{"v":-2.39294819094562,"d":"-2.39"},{"v":0.000254795335602841,"d":"0.00"},{"v":0.00787795328267033,"d":"0.01"},"down","yes"]
[173894,0,"chr7","-",47275154,47582144,"ENST00000311160",31,7618,"ENSG00000136205","TNS3","GO:0005829(cytosol);GO:0005925(focal adhesion);GO:0005515(protein binding);GO:0030054(cell junction);GO:0008284(positive regulation of cell proliferation);GO:0016477(cell migration);GO:0048286(lung alveolus development);GO:0035556(intracellular signal transduction);GO:0005622(intracellular)","NA","NA","NA","tensin 3 [Source:HGNC Symbol;Acc:HGNC:21616]",{"v":2.326831,"d":"2.33"},{"v":0.344127,"d":"0.34"},{"v":6.76154733572199,"d":"6.76"},{"v":2.75735343557932,"d":"2.76"},{"v":0.000257171292608324,"d":"0.00"},{"v":0.00793566479989299,"d":"0.01"},"up","yes"]
[72189,0,"chr16","+",31180110,31194871,"ENST00000254108",15,5119,"MSTRG.5887","FUS","GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0005654(nucleoplasm);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0042802(identical protein binding);GO:0000398(mRNA splicing, via spliceosome);GO:0003713(transcription coactivator activity);GO:0030331(estrogen receptor binding);GO:0031489(myosin V binding);GO:0035255(ionotropic glutamate receptor binding);GO:0046965(retinoid X receptor binding);GO:0046966(thyroid hormone receptor binding);GO:0071277(cellular response to calcium ion);GO:0005737(cytoplasm);GO:0005844(polysome);GO:0030425(dendrite);GO:0043025(neuronal cell body);GO:0043197(dendritic spine);GO:0043204(perikaryon);GO:0044327(dendritic spine head);GO:0048471(perinuclear region of cytoplasm)","05202(Transcriptional misregulation in cancers)","K13098","NA","FUS RNA binding protein [Source:HGNC Symbol;Acc:HGNC:4010]",{"v":10.521383,"d":"10.52"},{"v":1.578258,"d":"1.58"},{"v":6.66645314010764,"d":"6.67"},{"v":2.73691938537002,"d":"2.74"},{"v":0.000257463958031701,"d":"0.00"},{"v":0.00793566479989299,"d":"0.01"},"up","yes"]
[104227,0,"chr19","-",49907543,49929731,"ENST00000352066",3,2870,"ENSG00000213024","NUP62","GO:0006810(transport);GO:0051028(mRNA transport);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0015031(protein transport);GO:0043231(intracellular membrane-bounded organelle);GO:0006351(transcription, DNA-templated);GO:0031965(nuclear membrane);GO:0017056(structural constituent of nuclear pore);GO:0051169(nuclear transport);GO:0005643(nuclear pore);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0045893(positive regulation of transcription, DNA-templated);GO:0000922(spindle pole);GO:0005813(centrosome);GO:0005815(microtubule organizing center);GO:0042169(SH2 domain binding);GO:0008285(negative regulation of cell proliferation);GO:0075733(intracellular transport of virus);GO:0043657(host cell);GO:0003682(chromatin binding);GO:0016032(viral process);GO:0007098(centrosome cycle);GO:0043123(positive regulation of I-kappaB kinase/NF-kappaB signaling);GO:0009755(hormone-mediated signaling pathway);GO:0098534(centriole assembly);GO:0043130(ubiquitin binding);GO:0043066(negative regulation of apoptotic process);GO:0046601(positive regulation of centriole replication);GO:0008219(cell death);GO:0009966(regulation of signal transduction);GO:0005635(nuclear envelope);GO:0045840(positive regulation of mitotic nuclear division);GO:0030529(intracellular ribonucleoprotein complex);GO:0006406(mRNA export from nucleus);GO:0016925(protein sumoylation);GO:0006606(protein import into nucleus);GO:0060964(regulation of gene silencing by miRNA);GO:0006110(regulation of glycolytic process);GO:0006409(tRNA export from nucleus);GO:0007077(mitotic nuclear envelope disassembly);GO:0019083(viral transcription);GO:1900034(regulation of cellular response to heat);GO:0007080(mitotic metaphase plate congression);GO:0030159(receptor signaling complex scaffold activity);GO:0072686(mitotic spindle);GO:0090543(Flemming body);GO:0046966(thyroid hormone receptor binding);GO:0007166(cell surface receptor signaling pathway);GO:0045742(positive regulation of epidermal growth factor receptor signaling pathway);GO:0043069(negative regulation of programmed cell death);GO:0044613(nuclear pore central transport channel);GO:0005487(nucleocytoplasmic transporter activity);GO:0005543(phospholipid binding);GO:0007100(mitotic centrosome separation);GO:0046578(regulation of Ras protein signal transduction);GO:0060236(regulation of mitotic spindle organization);GO:0071426(ribonucleoprotein complex export from nucleus);GO:1903438(positive regulation of mitotic cytokinetic process);GO:1904781(positive regulation of protein localization to centrosome);GO:0019894(kinesin binding);GO:0030544(Hsp70 protein binding);GO:0051425(PTB domain binding);GO:0051879(Hsp90 protein binding);GO:0000278(mitotic cell cycle);GO:0007283(spermatogenesis);GO:0007569(cell aging);GO:0042059(negative regulation of epidermal growth factor receptor signaling pathway);GO:0042306(regulation of protein import into nucleus);GO:0043407(negative regulation of MAP kinase activity);GO:0046580(negative regulation of Ras protein signal transduction);GO:0070208(protein heterotrimerization);GO:0005642(annulate lamellae);GO:0043234(protein complex)","03013(RNA transport)","K14306","NA","nucleoporin 62 [Source:HGNC Symbol;Acc:HGNC:8066]",{"v":2.092149,"d":"2.09"},{"v":0.297034,"d":"0.30"},{"v":7.04346640451935,"d":"7.04"},{"v":2.81628561832405,"d":"2.82"},{"v":0.000257930585488861,"d":"0.00"},{"v":0.00793768339915019,"d":"0.01"},"up","yes"]
[82137,"j","chr17","-",35010042,35089264,"MSTRG.6694.6",6,2775,"MSTRG.6694","AC004223.3","NA","NA","NA","NA","NA",{"v":2.139234,"d":"2.14"},{"v":0.301921,"d":"0.30"},{"v":7.08540975950663,"d":"7.09"},{"v":2.82485128869927,"d":"2.82"},{"v":2.59003102342074E-4,"d":"0.00"},{"v":0.00795831271606361,"d":"0.01"},"up","yes"]
[118029,"j","chr2","+",201260521,201287586,"MSTRG.9357.18",9,2551,"MSTRG.9357","CASP8","NA","NA","NA","NA","NA",{"v":30.033045,"d":"30.03"},{"v":4.529905,"d":"4.53"},{"v":6.62995029697091,"d":"6.63"},{"v":2.72899805486541,"d":"2.73"},{"v":0.000259651568792834,"d":"0.00"},{"v":0.00796586859422107,"d":"0.01"},"up","yes"]
[54179,0,"chr14","-",34432789,34462356,"ENST00000298130",2,2777,"MSTRG.4310","SPTSSA","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0006629(lipid metabolic process);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0006665(sphingolipid metabolic process);GO:0005515(protein binding);GO:0030148(sphingolipid biosynthetic process);GO:0004758(serine C-palmitoyltransferase activity);GO:0046513(ceramide biosynthetic process);GO:0017059(serine C-palmitoyltransferase complex)","NA","NA","NA","serine palmitoyltransferase small subunit A [Source:HGNC Symbol;Acc:HGNC:20361]",{"v":0.789652,"d":"0.79"},{"v":4.069687,"d":"4.07"},{"v":0.194032612336035,"d":"0.19"},{"v":-2.36562893886014,"d":"-2.37"},{"v":0.00026236091909982,"d":"0.00"},{"v":0.00803652920611027,"d":"0.01"},"down","yes"]
[160138,0,"chr5","-",151029947,151081084,"ENST00000610535",17,2726,"MSTRG.12464","TNIP1","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0005515(protein binding);GO:0002755(MyD88-dependent toll-like receptor signaling pathway);GO:0006954(inflammatory response);GO:0042802(identical protein binding);GO:0050727(regulation of inflammatory response);GO:0043124(negative regulation of I-kappaB kinase/NF-kappaB signaling);GO:0070373(negative regulation of ERK1 and ERK2 cascade);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0005622(intracellular);GO:0016579(protein deubiquitination);GO:0045071(negative regulation of viral genome replication);GO:0050729(positive regulation of inflammatory response);GO:0006412(translation);GO:0006952(defense response);GO:0051019(mitogen-activated protein kinase binding);GO:0009101(glycoprotein biosynthetic process);GO:0007159(leukocyte cell-cell adhesion);GO:0031593(polyubiquitin binding);GO:0071222(cellular response to lipopolysaccharide);GO:0085032(modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade);GO:1903003(positive regulation of protein deubiquitination)","NA","NA","NA","TNFAIP3 interacting protein 1 [Source:HGNC Symbol;Acc:HGNC:16903]",{"v":0.842816,"d":"0.84"},{"v":4.344877,"d":"4.34"},{"v":0.193979254188323,"d":"0.19"},{"v":-2.36602572845459,"d":"-2.37"},{"v":0.000264119520941654,"d":"0.00"},{"v":0.00807789347819697,"d":"0.01"},"down","yes"]
[76586,0,"chr16","+",87391800,87404779,"ENST00000268607",4,2688,"MSTRG.6219","MAP1LC3B","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0005874(microtubule);GO:0006914(autophagy);GO:0031410(cytoplasmic vesicle);GO:0005829(cytosol);GO:0000421(autophagosome membrane);GO:0061024(membrane organization);GO:0005930(axoneme);GO:0000045(autophagosome assembly);GO:0006995(cellular response to nitrogen starvation);GO:0012505(endomembrane system);GO:0009267(cellular response to starvation);GO:0031625(ubiquitin protein ligase binding);GO:0005776(autophagosome);GO:0031090(organelle membrane);GO:0005739(mitochondrion);GO:0005622(intracellular);GO:0016236(macroautophagy);GO:0097352(autophagosome maturation);GO:0000422(mitophagy)","04216(Ferroptosis)","K10435","NA","microtubule associated protein 1 light chain 3 beta [Source:HGNC Symbol;Acc:HGNC:13352]",{"v":5.824402,"d":"5.82"},{"v":29.137154,"d":"29.14"},{"v":0.199896050245676,"d":"0.20"},{"v":-2.32267812879418,"d":"-2.32"},{"v":0.000264773973418035,"d":"0.00"},{"v":8.08541263270998E-3,"d":"0.01"},"down","yes"]
[77428,0,"chr17","-",1344272,1400378,"ENST00000264335",6,2211,"MSTRG.6275","YWHAE","GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0043547(positive regulation of GTPase activity);GO:0019904(protein domain specific binding);GO:0005515(protein binding);GO:0042470(melanosome);GO:0005925(focal adhesion);GO:0005829(cytosol);GO:0045296(cadherin binding);GO:0070062(extracellular exosome);GO:0017112(Rab guanyl-nucleotide exchange factor activity);GO:0061024(membrane organization);GO:0016032(viral process);GO:0000086(G2/M transition of mitotic cell cycle);GO:0010389(regulation of G2/M transition of mitotic cell cycle);GO:0097711(ciliary basal body docking);GO:0021762(substantia nigra development);GO:0046982(protein heterodimerization activity);GO:0044325(ion channel binding);GO:0019899(enzyme binding);GO:0000165(MAPK cascade);GO:1901016(regulation of potassium ion transmembrane transporter activity);GO:0035329(hippo signaling);GO:0035556(intracellular signal transduction);GO:0060306(regulation of membrane repolarization);GO:1900740(positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway);GO:0031625(ubiquitin protein ligase binding);GO:0042826(histone deacetylase binding);GO:1900034(regulation of cellular response to heat);GO:0034605(cellular response to heat);GO:0086091(regulation of heart rate by cardiac conduction);GO:0030659(cytoplasmic vesicle membrane);GO:0015459(potassium channel regulator activity);GO:0046827(positive regulation of protein export from nucleus);GO:0043154(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process);GO:0023026(MHC class II protein complex binding);GO:0086013(membrane repolarization during cardiac muscle cell action potential);GO:0051480(regulation of cytosolic calcium ion concentration);GO:0005886(plasma membrane);GO:0050815(phosphoserine residue binding);GO:0051219(phosphoprotein binding);GO:0005246(calcium channel regulator activity);GO:0032403(protein complex binding);GO:0001764(neuron migration);GO:0003064(regulation of heart rate by hormone);GO:0006605(protein targeting);GO:0021766(hippocampus development);GO:0021987(cerebral cortex development);GO:0035308(negative regulation of protein dephosphorylation);GO:1901020(negative regulation of calcium ion transmembrane transporter activity);GO:1902309(negative regulation of peptidyl-serine dephosphorylation);GO:1905913(negative regulation of calcium ion export from cell);GO:0005739(mitochondrion);GO:0005871(kinesin complex);GO:0030424(axon);GO:0090724(central region of growth cone)","04390(Hippo signaling pathway);04151(PI3K-Akt signaling pathway);04110(Cell cycle);04114(Oocyte meiosis);04722(Neurotrophin signaling pathway);05203(Viral carcinogenesis);05169(Epstein-Barr virus infection)","K06630","NA","tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon [Source:HGNC Symbol;Acc:HGNC:12851]",{"v":6.794494,"d":"6.79"},{"v":33.980694,"d":"33.98"},{"v":0.199951596044507,"d":"0.20"},{"v":-2.32227729787883,"d":"-2.32"},{"v":0.000265480765057825,"d":"0.00"},{"v":0.00809450443600038,"d":"0.01"},"down","yes"]
[187987,0,"chr8","-",143579728,143597428,"ENST00000533833",7,831,"MSTRG.14619","EEF1D","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0006412(translation);GO:0005829(cytosol);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0001650(fibrillar center);GO:0005783(endoplasmic reticulum);GO:0005515(protein binding);GO:0004871(signal transducer activity);GO:0003746(translation elongation factor activity);GO:0006414(translational elongation);GO:0005853(eukaryotic translation elongation factor 1 complex);GO:0007165(signal transduction);GO:0045296(cadherin binding);GO:0043123(positive regulation of I-kappaB kinase/NF-kappaB signaling);GO:0008135(translation factor activity, RNA binding);GO:0071479(cellular response to ionizing radiation)","05168(Herpes simplex infection)","NA","NA","eukaryotic translation elongation factor 1 delta [Source:HGNC Symbol;Acc:HGNC:3211]",{"v":1.274153,"d":"1.27"},{"v":6.754896,"d":"6.75"},{"v":0.188626590253943,"d":"0.19"},{"v":-2.40639503115697,"d":"-2.41"},{"v":2.68241285308517E-4,"d":"0.00"},{"v":0.00816609008259219,"d":"0.01"},"down","yes"]
[113036,"j","chr2","+",102418601,102452568,"MSTRG.9018.1",12,2819,"MSTRG.9018","IL18RAP","NA","NA","NA","NA","NA",{"v":1.682494,"d":"1.68"},{"v":8.477758,"d":"8.48"},{"v":0.198459781465807,"d":"0.20"},{"v":-2.33308142484265,"d":"-2.33"},{"v":0.000272812150106159,"d":"0.00"},{"v":0.0082924836041485,"d":"0.01"},"down","yes"]
[127434,0,"chr21","-",41988637,42010387,"ENST00000398511",2,5608,"ENSG00000173276","ZBTB21","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0008327(methyl-CpG binding)","NA","NA","NA","zinc finger and BTB domain containing 21 [Source:HGNC Symbol;Acc:HGNC:13083]",{"v":1.484006,"d":"1.48"},{"v":0.214305,"d":"0.21"},{"v":6.92473810690371,"d":"6.92"},{"v":2.79175950957107,"d":"2.79"},{"v":0.000275914208394197,"d":"0.00"},{"v":0.00836648893302296,"d":"0.01"},"up","yes"]
[41210,0,"chr12","-",49185010,49186864,"ENST00000550767",3,1384,"MSTRG.3349","TUBA1A","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005525(GTP binding);GO:0000166(nucleotide binding);GO:0003924(GTPase activity);GO:0015630(microtubule cytoskeleton);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0005200(structural constituent of cytoskeleton);GO:0007010(cytoskeleton organization);GO:0005874(microtubule);GO:0007017(microtubule-based process);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0055037(recycling endosome);GO:0000086(G2/M transition of mitotic cell cycle);GO:0010389(regulation of G2/M transition of mitotic cell cycle);GO:0097711(ciliary basal body docking);GO:0036464(cytoplasmic ribonucleoprotein granule);GO:0005198(structural molecule activity);GO:0030705(cytoskeleton-dependent intracellular transport);GO:0051301(cell division);GO:0019904(protein domain specific binding);GO:0005881(cytoplasmic microtubule);GO:0043209(myelin sheath);GO:0045121(membrane raft)","04145(Phagosome);04210(Apoptosis);04530(Tight junction);04540(Gap junction);05130(Pathogenic Escherichia coli infection)","K07374","NA","tubulin alpha 1a [Source:HGNC Symbol;Acc:HGNC:20766]",{"v":20.892414,"d":"20.89"},{"v":3.141845,"d":"3.14"},{"v":6.64972778733515,"d":"6.65"},{"v":2.7332952837868,"d":"2.73"},{"v":0.000276092443564989,"d":"0.00"},{"v":0.00836648893302296,"d":"0.01"},"up","yes"]
[191326,0,"chr9","-",83244622,83538438,"ENST00000304195",14,5297,"ENSG00000172159","FRMD3","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005856(cytoskeleton);GO:0008092(cytoskeletal protein binding);GO:0005200(structural constituent of cytoskeleton);GO:0031032(actomyosin structure organization)","NA","NA","NA","FERM domain containing 3 [Source:HGNC Symbol;Acc:HGNC:24125]",{"v":1.155145,"d":"1.16"},{"v":0.164187,"d":"0.16"},{"v":7.03554483607107,"d":"7.04"},{"v":2.81466215080533,"d":"2.81"},{"v":2.77643157270131E-4,"d":"0.00"},{"v":0.00840061589611828,"d":"0.01"},"up","yes"]
[161196,"j","chr5","+",173888318,173959809,"MSTRG.12547.2",9,7254,"MSTRG.12547","CPEB4","NA","NA","NA","NA","NA",{"v":4.520041,"d":"4.52"},{"v":0.684048,"d":"0.68"},{"v":6.60778337192712,"d":"6.61"},{"v":2.72416639054529,"d":"2.72"},{"v":0.000279384755028807,"d":"0.00"},{"v":0.00842789231974546,"d":"0.01"},"up","yes"]
[124515,0,"chr20","+",49278178,49289260,"ENST00000450535",6,1075,"MSTRG.9812","ZFAS1","NA","NA","NA","NA","ZNFX1 antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:33101]",{"v":0.967156,"d":"0.97"},{"v":5.075735,"d":"5.08"},{"v":0.190545014662901,"d":"0.19"},{"v":-2.39179623229067,"d":"-2.39"},{"v":0.000279396470676826,"d":"0.00"},{"v":0.00842789231974546,"d":"0.01"},"down","yes"]
[143862,0,"chr3","+",186783577,186789897,"ENST00000440191",11,1889,"MSTRG.11403","EIF4A2","GO:0003676(nucleic acid binding);GO:0005524(ATP binding);GO:0003723(RNA binding);GO:0003743(translation initiation factor activity);GO:0006412(translation);GO:0006413(translational initiation);GO:0000166(nucleotide binding);GO:0016787(hydrolase activity);GO:0004386(helicase activity);GO:0005515(protein binding);GO:0048471(perinuclear region of cytoplasm);GO:0005730(nucleolus);GO:0005829(cytosol);GO:0004004(ATP-dependent RNA helicase activity);GO:0010501(RNA secondary structure unwinding);GO:0000289(nuclear-transcribed mRNA poly(A) tail shortening);GO:0016032(viral process);GO:0016887(ATPase activity);GO:0006446(regulation of translational initiation);GO:0016281(eukaryotic translation initiation factor 4F complex);GO:1900260(negative regulation of RNA-directed 5'-3' RNA polymerase activity);GO:1990830(cellular response to leukemia inhibitory factor)","03013(RNA transport)","NA","NA","eukaryotic translation initiation factor 4A2 [Source:HGNC Symbol;Acc:HGNC:3284]",{"v":5.254881,"d":"5.25"},{"v":26.140459,"d":"26.14"},{"v":0.201024817506074,"d":"0.20"},{"v":-2.31455447466349,"d":"-2.31"},{"v":0.000285125946707069,"d":"0.00"},{"v":0.00858762897022751,"d":"0.01"},"down","yes"]
[19698,"j","chr10","+",35449711,35571080,"MSTRG.1660.9",10,2883,"MSTRG.1660","CCNY","NA","NA","NA","NA","NA",{"v":16.293024,"d":"16.29"},{"v":2.481668,"d":"2.48"},{"v":6.56535201324271,"d":"6.57"},{"v":2.7148723659003,"d":"2.71"},{"v":0.000289670548929511,"d":"0.00"},{"v":0.00871124745017805,"d":"0.01"},"up","yes"]
[10601,0,"chr1","-",150574551,150579738,"ENST00000620947",4,3626,"MSTRG.917","MCL1","GO:0043066(negative regulation of apoptotic process);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0071806(protein transmembrane transport);GO:0005739(mitochondrion);GO:0042981(regulation of apoptotic process);GO:0005829(cytosol);GO:0005515(protein binding);GO:0006915(apoptotic process);GO:0007275(multicellular organism development);GO:0005741(mitochondrial outer membrane);GO:0030154(cell differentiation);GO:0005654(nucleoplasm);GO:0046982(protein heterodimerization activity);GO:0001709(cell fate determination);GO:0042803(protein homodimerization activity);GO:2000811(negative regulation of anoikis);GO:0008630(intrinsic apoptotic signaling pathway in response to DNA damage);GO:0010507(negative regulation of autophagy);GO:0034097(response to cytokine);GO:0019725(cellular homeostasis);GO:2001240(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand);GO:2001020(regulation of response to DNA damage stimulus);GO:0097192(extrinsic apoptotic signaling pathway in absence of ligand);GO:0097136(Bcl-2 family protein complex);GO:0015266(protein channel activity);GO:0051434(BH3 domain binding);GO:0008637(apoptotic mitochondrial changes);GO:1903378(positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway);GO:2001243(negative regulation of intrinsic apoptotic signaling pathway);GO:0005759(mitochondrial matrix)","04630(Jak-STAT signaling pathway);04151(PI3K-Akt signaling pathway);04210(Apoptosis);05206(MicroRNAs in cancer)","K02539","NA","MCL1, BCL2 family apoptosis regulator [Source:HGNC Symbol;Acc:HGNC:6943]",{"v":0.380219,"d":"0.38"},{"v":1.963848,"d":"1.96"},{"v":0.193609179529169,"d":"0.19"},{"v":-2.36878073862167,"d":"-2.37"},{"v":0.000290793058270895,"d":"0.00"},{"v":0.00873173450237399,"d":"0.01"},"down","yes"]
[10248,0,"chr1","-",148102047,148127288,"ENST00000614015",21,4630,"MSTRG.882","NBPF11","GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0005737(cytoplasm)","NA","NA","NA","NBPF member 11 [Source:HGNC Symbol;Acc:HGNC:31993]",{"v":1.208248,"d":"1.21"},{"v":0.173724,"d":"0.17"},{"v":6.95498606985794,"d":"6.95"},{"v":2.79804762519641,"d":"2.80"},{"v":0.000291904778174865,"d":"0.00"},{"v":0.00874843356270883,"d":"0.01"},"up","yes"]
[69987,"j","chr16","-",15593901,15643060,"MSTRG.5695.1",27,8119,"MSTRG.5695","MARF1","NA","NA","NA","NA","NA",{"v":3.388548,"d":"3.39"},{"v":0.514094,"d":"0.51"},{"v":6.59130042365793,"d":"6.59"},{"v":2.72056312831028,"d":"2.72"},{"v":0.000292233403322748,"d":"0.00"},{"v":0.00874843356270883,"d":"0.01"},"up","yes"]
[71789,0,"chr16","-",30114105,30123294,"ENST00000263025",9,1861,"MSTRG.5825","MAPK3","GO:0070374(positive regulation of ERK1 and ERK2 cascade);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0001934(positive regulation of protein phosphorylation);GO:0030509(BMP signaling pathway);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0016740(transferase activity);GO:0004707(MAP kinase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0005794(Golgi apparatus);GO:0005829(cytosol);GO:0005739(mitochondrion);GO:0005886(plasma membrane);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0007049(cell cycle);GO:0006915(apoptotic process);GO:0005901(caveola);GO:0005925(focal adhesion);GO:0038095(Fc-epsilon receptor signaling pathway);GO:0038096(Fc-gamma receptor signaling pathway involved in phagocytosis);GO:0005654(nucleoplasm);GO:0070062(extracellular exosome);GO:0000165(MAPK cascade);GO:0005769(early endosome);GO:0016032(viral process);GO:0005770(late endosome);GO:0019902(phosphatase binding);GO:0001784(phosphotyrosine residue binding);GO:0004708(MAP kinase kinase activity);GO:0097110(scaffold protein binding);GO:0000187(activation of MAPK activity);GO:0000189(MAPK import into nucleus);GO:0002741(positive regulation of cytokine secretion involved in immune response);GO:0006351(transcription, DNA-templated);GO:0006461(protein complex assembly);GO:0006974(cellular response to DNA damage stimulus);GO:0009636(response to toxic substance);GO:0009887(animal organ morphogenesis);GO:0010759(positive regulation of macrophage chemotaxis);GO:0014032(neural crest cell development);GO:0018105(peptidyl-serine phosphorylation);GO:0019233(sensory perception of pain);GO:0019369(arachidonic acid metabolic process);GO:0030278(regulation of ossification);GO:0030641(regulation of cellular pH);GO:0030878(thyroid gland development);GO:0031663(lipopolysaccharide-mediated signaling pathway);GO:0032496(response to lipopolysaccharide);GO:0035556(intracellular signal transduction);GO:0042473(outer ear morphogenesis);GO:0043330(response to exogenous dsRNA);GO:0045727(positive regulation of translation);GO:0045893(positive regulation of transcription, DNA-templated);GO:0048538(thymus development);GO:0051090(regulation of sequence-specific DNA binding transcription factor activity);GO:0051216(cartilage development);GO:0060020(Bergmann glial cell differentiation);GO:0060324(face development);GO:0060425(lung morphogenesis);GO:0060440(trachea formation);GO:0061308(cardiac neural crest cell development involved in heart development);GO:0070371(ERK1 and ERK2 cascade);GO:1904417(positive regulation of xenophagy);GO:1905050(positive regulation of metallopeptidase activity);GO:2000657(negative regulation of apolipoprotein binding);GO:0031143(pseudopodium);GO:0043234(protein complex);GO:0071260(cellular response to mechanical stimulus);GO:0030168(platelet activation);GO:0007411(axon guidance);GO:0014066(regulation of phosphatidylinositol 3-kinase signaling);GO:0032212(positive regulation of telomere maintenance via telomerase);GO:0051973(positive regulation of telomerase activity);GO:1904355(positive regulation of telomere capping);GO:0006975(DNA damage induced protein phosphorylation);GO:0034614(cellular response to reactive oxygen species);GO:0071276(cellular response to cadmium ion);GO:0006361(transcription initiation from RNA polymerase I promoter);GO:0005635(nuclear envelope);GO:1900034(regulation of cellular response to heat);GO:0008543(fibroblast growth factor receptor signaling pathway);GO:0051493(regulation of cytoskeleton organization);GO:0070498(interleukin-1-mediated signaling pathway);GO:0060397(JAK-STAT cascade involved in growth hormone signaling pathway);GO:2000641(regulation of early endosome to late endosome transport);GO:0033129(positive regulation of histone phosphorylation);GO:0035066(positive regulation of histone acetylation);GO:0038083(peptidyl-tyrosine autophosphorylation);GO:0010628(positive regulation of gene expression);GO:1903351(cellular response to dopamine);GO:0070849(response to epidermal growth factor);GO:0034198(cellular response to amino acid starvation);GO:0031281(positive regulation of cyclase activity);GO:0032872(regulation of stress-activated MAPK cascade);GO:0051403(stress-activated MAPK cascade);GO:0072584(caveolin-mediated endocytosis);GO:0090170(regulation of Golgi inheritance);GO:0005622(intracellular)","04014(Ras signaling pathway);04015(Rap1 signaling pathway);04010(MAPK signaling pathway);04012(ErbB signaling pathway);04350(TGF-beta signaling pathway);04370(VEGF signaling pathway);04371(Apelin signaling pathway);04668(TNF signaling pathway);04066(HIF-1 signaling pathway);04068(FoxO signaling pathway);04072(Phospholipase D signaling pathway);04071(Sphingolipid signaling pathway);04024(cAMP signaling pathway);04022(cGMP - PKG signaling pathway);04151(PI3K-Akt signaling pathway);04150(mTOR signaling pathway);04140(Autophagy - animal);04114(Oocyte meiosis);04210(Apoptosis);04218(Cellular senescence);04510(Focal adhesion);04520(Adherens junction);04540(Gap junction);04550(Signaling pathways regulating pluripotency of stem cells);04810(Regulation of actin cytoskeleton);04611(Platelet activation);04620(Toll-like receptor signaling pathway);04621(NOD-like receptor signaling pathway);04650(Natural killer cell mediated cytotoxicity);04660(T cell receptor signaling pathway);04658(Th1 and Th2 cell differentiation);04659(Th17 cell differentiation);04657(IL-17 signaling pathway);04662(B cell receptor signaling pathway);04664(Fc epsilon RI signaling pathway);04666(Fc gamma R-mediated phagocytosis);04062(Chemokine signaling pathway);04910(Insulin signaling pathway);04912(GnRH signaling pathway);04915(Estrogen signaling pathway);04914(Progesterone-mediated oocyte maturation);04917(Prolactin signaling pathway);04921(Oxytocin signaling pathway);04926(Relaxin signaling pathway);04919(Thyroid hormone signaling pathway);04916(Melanogenesis);04261(Adrenergic signaling in cardiomyocytes);04270(Vascular smooth muscle contraction);04960(Aldosterone-regulated sodium reabsorption);04724(Glutamatergic synapse);04725(Cholinergic synapse);04726(Serotonergic synapse);04720(Long-term potentiation);04730(Long-term depression);04723(Retrograde endocannabinoid signaling);04722(Neurotrophin signaling pathway);04360(Axon guidance);04380(Osteoclast differentiation);04713(Circadian entrainment);05200(Pathways in cancer);05230(Central carbon metabolism in cancer);05231(Choline metabolism in cancer);05205(Proteoglycans in cancer);05203(Viral carcinogenesis);05210(Colorectal cancer);05212(Pancreatic cancer);05225(Hepatocellular carcinoma);05226(Gastric cancer);05214(Glioma);05216(Thyroid cancer);05221(Acute myeloid leukemia);05220(Chronic myeloid leukemia);05218(Melanoma);05211(Renal cell carcinoma);05219(Bladder cancer);05215(Prostate cancer);05213(Endometrial cancer);05224(Breast cancer);05223(Non-small cell lung cancer);05010(Alzheimer's disease);05020(Prion diseases);05034(Alcoholism);04930(Type II diabetes mellitus);04933(AGE-RAGE signaling pathway in diabetic complications);05132(Salmonella infection);05131(Shigellosis);05133(Pertussis);05152(Tuberculosis);05164(Influenza A);05161(Hepatitis B);05160(Hepatitis C);05167(Kaposi's sarcoma-associated herpesvirus infection);05165(Human papillomavirus infection);05145(Toxoplasmosis);05140(Leishmaniasis);05142(Chagas disease (American trypanosomiasis));01521(EGFR tyrosine kinase inhibitor resistance);01524(Platinum drug resistance);01522(Endocrine resistance)","K04371","EC:2.7.11.24","mitogen-activated protein kinase 3 [Source:HGNC Symbol;Acc:HGNC:6877]",{"v":3.969804,"d":"3.97"},{"v":19.725758,"d":"19.73"},{"v":0.201249756790081,"d":"0.20"},{"v":-2.31294105515306,"d":"-2.31"},{"v":0.000294151460127568,"d":"0.00"},{"v":0.00879255150000651,"d":"0.01"},"down","yes"]
[47349,0,"chr12","-",120196699,120201099,"ENST00000551150",7,1344,"MSTRG.3785","RPLP0","GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0006412(translation);GO:0005783(endoplasmic reticulum);GO:0005829(cytosol);GO:0030529(intracellular ribonucleoprotein complex);GO:0005622(intracellular);GO:0005840(ribosome);GO:0005515(protein binding);GO:0003735(structural constituent of ribosome);GO:0042254(ribosome biogenesis);GO:0005925(focal adhesion);GO:0070062(extracellular exosome);GO:0016032(viral process);GO:0022625(cytosolic large ribosomal subunit);GO:0035722(interleukin-12-mediated signaling pathway);GO:0006413(translational initiation);GO:0006364(rRNA processing);GO:0036464(cytoplasmic ribonucleoprotein granule);GO:0000184(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay);GO:0019083(viral transcription);GO:0006614(SRP-dependent cotranslational protein targeting to membrane)","03010(Ribosome)","NA","NA","ribosomal protein lateral stalk subunit P0 [Source:HGNC Symbol;Acc:HGNC:10371]",{"v":32.990108,"d":"32.99"},{"v":162.316132,"d":"162.32"},{"v":0.20324602116566,"d":"0.20"},{"v":-2.29870098514921,"d":"-2.30"},{"v":2.94993338373709E-4,"d":"0.00"},{"v":0.00880441656069224,"d":"0.01"},"down","yes"]
[18460,0,"chr10","+",11165484,11329289,"ENST00000609870",10,1549,"MSTRG.1548","CELF2","GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0006397(mRNA processing);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0006396(RNA processing);GO:0006376(mRNA splice site selection);GO:0008016(regulation of heart contraction);GO:0036002(pre-mRNA binding)","NA","NA","NA","CUGBP Elav-like family member 2 [Source:HGNC Symbol;Acc:HGNC:2550]",{"v":8.299574,"d":"8.30"},{"v":1.237643,"d":"1.24"},{"v":6.70595155468903,"d":"6.71"},{"v":2.74544206081402,"d":"2.75"},{"v":0.000296498523067831,"d":"0.00"},{"v":0.0088360132145576,"d":"0.01"},"up","yes"]
[89502,0,"chr17","-",81868870,81871337,"ENST00000582984",5,823,"MSTRG.7335","ARHGDIA","GO:0005737(cytoplasm);GO:0050790(regulation of catalytic activity);GO:0043547(positive regulation of GTPase activity);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0005096(GTPase activator activity);GO:0005094(Rho GDP-dissociation inhibitor activity);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0051056(regulation of small GTPase mediated signal transduction);GO:0043066(negative regulation of apoptotic process);GO:0071526(semaphorin-plexin signaling pathway);GO:2000249(regulation of actin cytoskeleton reorganization);GO:0006928(movement of cell or subcellular component);GO:0050772(positive regulation of axonogenesis);GO:0035023(regulation of Rho protein signal transduction);GO:0050771(negative regulation of axonogenesis);GO:0007162(negative regulation of cell adhesion);GO:0005504(fatty acid binding);GO:0017048(Rho GTPase binding);GO:0019901(protein kinase binding);GO:0051879(Hsp90 protein binding);GO:0007266(Rho protein signal transduction);GO:0008360(regulation of cell shape);GO:0030336(negative regulation of cell migration);GO:0032880(regulation of protein localization);GO:0071260(cellular response to mechanical stimulus);GO:0071407(cellular response to organic cyclic compound);GO:0071461(cellular response to redox state);GO:0001772(immunological synapse);GO:0005615(extracellular space);GO:0005634(nucleus);GO:0016020(membrane)","04962(Vasopressin-regulated water reabsorption);04722(Neurotrophin signaling pathway)","NA","NA","Rho GDP dissociation inhibitor alpha [Source:HGNC Symbol;Acc:HGNC:678]",{"v":1.390681,"d":"1.39"},{"v":7.218402,"d":"7.22"},{"v":0.192657737820642,"d":"0.19"},{"v":-2.37588796395719,"d":"-2.38"},{"v":0.000298493816408232,"d":"0.00"},{"v":0.00888209870539264,"d":"0.01"},"down","yes"]
[46503,0,"chr12","-",109947322,109996296,"ENST00000547815",15,2989,"MSTRG.3708","GIT2","GO:0046872(metal ion binding);GO:0043547(positive regulation of GTPase activity);GO:0005515(protein binding);GO:0005096(GTPase activator activity);GO:0005654(nucleoplasm);GO:0005925(focal adhesion);GO:0008277(regulation of G-protein coupled receptor protein signaling pathway);GO:0016301(kinase activity);GO:0016310(phosphorylation)","04144(Endocytosis)","K12487","NA","GIT ArfGAP 2 [Source:HGNC Symbol;Acc:HGNC:4273]",{"v":11.292036,"d":"11.29"},{"v":1.727331,"d":"1.73"},{"v":6.53727397933575,"d":"6.54"},{"v":2.70868916227303,"d":"2.71"},{"v":0.000303351958523688,"d":"0.00"},{"v":0.00901310593883895,"d":"0.01"},"up","yes"]
[78183,0,"chr17","-",4959226,4967790,"ENST00000575142",6,1094,"MSTRG.6346","SPAG7","GO:0003676(nucleic acid binding);GO:0005634(nucleus)","NA","NA","NA","sperm associated antigen 7 [Source:HGNC Symbol;Acc:HGNC:11216]",{"v":6.152441,"d":"6.15"},{"v":0.89147,"d":"0.89"},{"v":6.9014560220759,"d":"6.90"},{"v":2.78690076395284,"d":"2.79"},{"v":0.000304570057244411,"d":"0.00"},{"v":0.0090357305738417,"d":"0.01"},"up","yes"]
[5399,0,"chr1","-",44850778,44986610,"ENST00000360403",12,1659,"ENSG00000070785","EIF2B3","GO:0005737(cytoplasm);GO:0003743(translation initiation factor activity);GO:0006412(translation);GO:0006413(translational initiation);GO:0009058(biosynthetic process);GO:0043547(positive regulation of GTPase activity);GO:0016779(nucleotidyltransferase activity);GO:0005085(guanyl-nucleotide exchange factor activity);GO:0005515(protein binding);GO:0005829(cytosol);GO:0009408(response to heat);GO:0005851(eukaryotic translation initiation factor 2B complex);GO:0032057(negative regulation of translational initiation in response to stress);GO:0009749(response to glucose);GO:0008135(translation factor activity, RNA binding);GO:0043434(response to peptide hormone);GO:0014003(oligodendrocyte development);GO:0051716(cellular response to stimulus);GO:0021766(hippocampus development)","03013(RNA transport)","K03241","NA","eukaryotic translation initiation factor 2B subunit gamma [Source:HGNC Symbol;Acc:HGNC:3259]",{"v":0.655994,"d":"0.66"},{"v":3.411624,"d":"3.41"},{"v":0.192282033424551,"d":"0.19"},{"v":-2.3787041294027,"d":"-2.38"},{"v":3.05162196352469E-4,"d":"0.00"},{"v":0.00903974482248902,"d":"0.01"},"down","yes"]
[129512,0,"chr22","+",24270840,24417740,"ENST00000314328",17,6756,"MSTRG.10311","SPECC1L","GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0051301(cell division);GO:0015629(actin cytoskeleton);GO:0005856(cytoskeleton);GO:0007049(cell cycle);GO:0005921(gap junction);GO:0030054(cell junction);GO:0005819(spindle);GO:0007155(cell adhesion)","NA","NA","NA","sperm antigen with calponin homology and coiled-coil domains 1 like [Source:HGNC Symbol;Acc:HGNC:29022]",{"v":4.160239,"d":"4.16"},{"v":0.635912,"d":"0.64"},{"v":6.5421614940432,"d":"6.54"},{"v":2.70976737296083,"d":"2.71"},{"v":0.00030670274930405,"d":"0.00"},{"v":0.00907179970587227,"d":"0.01"},"up","yes"]
[188156,0,"chr8","-",143915147,143939590,"ENST00000345136",32,14803,"MSTRG.14615","PLEC","GO:0003723(RNA binding);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0003779(actin binding);GO:0005925(focal adhesion);GO:0045111(intermediate filament cytoskeleton);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0008092(cytoskeletal protein binding);GO:0030054(cell junction);GO:0045296(cadherin binding);GO:0070062(extracellular exosome);GO:0042383(sarcolemma);GO:0031012(extracellular matrix);GO:0005886(plasma membrane);GO:0008307(structural constituent of muscle);GO:0030506(ankyrin binding);GO:0031581(hemidesmosome assembly);GO:0030056(hemidesmosome);GO:0043034(costamere);GO:0016528(sarcoplasm);GO:0005903(brush border);GO:0043292(contractile fiber)","NA","NA","NA","plectin [Source:HGNC Symbol;Acc:HGNC:9069]",{"v":6.127512,"d":"6.13"},{"v":0.948149,"d":"0.95"},{"v":6.46260450625376,"d":"6.46"},{"v":2.6921157053208,"d":"2.69"},{"v":0.000310898610866042,"d":"0.00"},{"v":0.00917477276950815,"d":"0.01"},"up","yes"]
[99890,0,"chr19","-",34956354,34964049,"ENST00000404801",4,3888,"ENSG00000180884","ZNF792","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0005622(intracellular);GO:0005515(protein binding);GO:0042802(identical protein binding)","NA","NA","NA","zinc finger protein 792 [Source:HGNC Symbol;Acc:HGNC:24751]",{"v":0.302063,"d":"0.30"},{"v":1.570432,"d":"1.57"},{"v":0.192343890088842,"d":"0.19"},{"v":-2.37824009253918,"d":"-2.38"},{"v":0.000311111407334747,"d":"0.00"},{"v":0.00917477276950815,"d":"0.01"},"down","yes"]
[24360,0,"chr10","+",128047631,128085855,"ENST00000479896",18,5736,"MSTRG.2045","PTPRE","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016787(hydrolase activity);GO:0004725(protein tyrosine phosphatase activity);GO:0016791(phosphatase activity);GO:0006470(protein dephosphorylation);GO:0016311(dephosphorylation);GO:0035335(peptidyl-tyrosine dephosphorylation);GO:0005886(plasma membrane);GO:0004721(phosphoprotein phosphatase activity);GO:0005515(protein binding);GO:0046627(negative regulation of insulin receptor signaling pathway);GO:0005001(transmembrane receptor protein tyrosine phosphatase activity)","NA","NA","NA","protein tyrosine phosphatase, receptor type E [Source:HGNC Symbol;Acc:HGNC:9669]",{"v":0.1748,"d":"0.17"},{"v":0.909396,"d":"0.91"},{"v":0.192215492480723,"d":"0.19"},{"v":-2.37920347352934,"d":"-2.38"},{"v":3.22105443927563E-4,"d":"0.00"},{"v":0.00948485494708127,"d":"0.01"},"down","yes"]
[28523,0,"chr11","+",46347588,46380367,"ENST00000318201",30,3213,"MSTRG.2358","DGKZ","GO:0005737(cytoplasm);GO:0005634(nucleus);GO:0016607(nuclear speck);GO:0016020(membrane);GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0035556(intracellular signal transduction);GO:0008152(metabolic process);GO:0003951(NAD+ kinase activity);GO:0005886(plasma membrane);GO:0004143(diacylglycerol kinase activity);GO:0007205(protein kinase C-activating G-protein coupled receptor signaling pathway);GO:0005515(protein binding);GO:0030027(lamellipodium);GO:0030168(platelet activation);GO:0016477(cell migration);GO:0046339(diacylglycerol metabolic process);GO:0046834(lipid phosphorylation);GO:0046486(glycerolipid metabolic process);GO:0005622(intracellular)","00561(Glycerolipid metabolism);00564(Glycerophospholipid metabolism);04070(Phosphatidylinositol signaling system);04072(Phospholipase D signaling pathway);05231(Choline metabolism in cancer)","K00901","EC:2.7.1.107","diacylglycerol kinase zeta [Source:HGNC Symbol;Acc:HGNC:2857]",{"v":1.933448,"d":"1.93"},{"v":0.282741,"d":"0.28"},{"v":6.83823004092084,"d":"6.84"},{"v":2.7736229564527,"d":"2.77"},{"v":0.000325977724229928,"d":"0.00"},{"v":0.00958266888466945,"d":"0.01"},"up","yes"]
[68954,0,"chr16","-",3725054,3880726,"ENST00000262367",31,10803,"MSTRG.5589","CREBBP","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0005654(nucleoplasm);GO:0016740(transferase activity);GO:0003713(transcription coactivator activity);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0016746(transferase activity, transferring acyl groups);GO:0005515(protein binding);GO:0000123(histone acetyltransferase complex);GO:0007165(signal transduction);GO:0016604(nuclear body);GO:0048511(rhythmic process);GO:0004402(histone acetyltransferase activity);GO:0045893(positive regulation of transcription, DNA-templated);GO:0003712(transcription cofactor activity);GO:0016573(histone acetylation);GO:0031648(protein destabilization);GO:0002223(stimulatory C-type lectin receptor signaling pathway);GO:0061418(regulation of transcription from RNA polymerase II promoter in response to hypoxia);GO:0003682(chromatin binding);GO:0001666(response to hypoxia);GO:0016032(viral process);GO:0004871(signal transducer activity);GO:0008134(transcription factor binding);GO:0042981(regulation of apoptotic process);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:1904837(beta-catenin-TCF complex assembly);GO:0000790(nuclear chromatin);GO:0006367(transcription initiation from RNA polymerase II promoter);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0001085(RNA polymerase II transcription factor binding);GO:0006461(protein complex assembly);GO:0042592(homeostatic process);GO:0007219(Notch signaling pathway);GO:0042733(embryonic digit morphogenesis);GO:0001078(transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0001102(RNA polymerase II activating transcription factor binding);GO:0001191(transcriptional repressor activity, RNA polymerase II transcription factor binding);GO:0032481(positive regulation of type I interferon production);GO:0002039(p53 binding);GO:0019216(regulation of lipid metabolic process);GO:1900034(regulation of cellular response to heat);GO:0003684(damaged DNA binding);GO:0000987(core promoter proximal region sequence-specific DNA binding);GO:0034644(cellular response to UV);GO:0045637(regulation of myeloid cell differentiation);GO:0001105(RNA polymerase II transcription coactivator activity);GO:0016407(acetyltransferase activity);GO:0006473(protein acetylation);GO:0034212(peptide N-acetyltransferase activity);GO:0018076(N-terminal peptidyl-lysine acetylation);GO:0043426(MRF binding);GO:0008589(regulation of smoothened signaling pathway)","04310(Wnt signaling pathway);04330(Notch signaling pathway);04350(TGF-beta signaling pathway);04630(Jak-STAT signaling pathway);04066(HIF-1 signaling pathway);04068(FoxO signaling pathway);04024(cAMP signaling pathway);04110(Cell cycle);04520(Adherens junction);04922(Glucagon signaling pathway);04919(Thyroid hormone signaling pathway);04916(Melanogenesis);04720(Long-term potentiation);05200(Pathways in cancer);05206(MicroRNAs in cancer);05203(Viral carcinogenesis);05211(Renal cell carcinoma);05215(Prostate cancer);05016(Huntington's disease);05152(Tuberculosis);05166(HTLV-I infection);05164(Influenza A);05161(Hepatitis B);05168(Herpes simplex infection);05167(Kaposi's sarcoma-associated herpesvirus infection);05169(Epstein-Barr virus infection);05165(Human papillomavirus infection)","K04498","EC:2.3.1.48","CREB binding protein [Source:HGNC Symbol;Acc:HGNC:2348]",{"v":21.748709,"d":"21.75"},{"v":3.395297,"d":"3.40"},{"v":6.40553948594188,"d":"6.41"},{"v":2.67932008202931,"d":"2.68"},{"v":0.000326614630550326,"d":"0.00"},{"v":0.00958266888466945,"d":"0.01"},"up","yes"]
[52811,"j","chr14","+",22456013,22466583,"MSTRG.4230.4",5,2246,"MSTRG.4230","TRDC","NA","NA","NA","NA","NA",{"v":0.94828,"d":"0.95"},{"v":4.736962,"d":"4.74"},{"v":0.20018737747949,"d":"0.20"},{"v":-2.32057708485855,"d":"-2.32"},{"v":0.000327346998507461,"d":"0.00"},{"v":0.00958266888466945,"d":"0.01"},"down","yes"]
[184158,0,"chr8","+",60678778,60868028,"ENST00000423902",38,11568,"ENSG00000171316","CHD7","GO:0005634(nucleus);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0016787(hydrolase activity);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0016569(covalent chromatin modification);GO:0004386(helicase activity);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0005730(nucleolus);GO:0006364(rRNA processing);GO:0016817(hydrolase activity, acting on acid anhydrides);GO:0003682(chromatin binding);GO:0060021(palate development);GO:0003007(heart morphogenesis);GO:0001501(skeletal system development);GO:0001701(in utero embryonic development);GO:0060041(retina development in camera-type eye);GO:0021545(cranial nerve development);GO:0048806(genitalia development);GO:0060324(face development);GO:0030217(T cell differentiation);GO:0060173(limb development);GO:0050890(cognition);GO:0007417(central nervous system development);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:1990841(promoter-specific chromatin binding);GO:0001568(blood vessel development);GO:0001974(blood vessel remodeling);GO:0003222(ventricular trabecula myocardium morphogenesis);GO:0003226(right ventricular compact myocardium morphogenesis);GO:0006338(chromatin remodeling);GO:0007512(adult heart development);GO:0007605(sensory perception of sound);GO:0007626(locomotory behavior);GO:0007628(adult walking behavior);GO:0008015(blood circulation);GO:0010880(regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum);GO:0021553(olfactory nerve development);GO:0021772(olfactory bulb development);GO:0030540(female genitalia development);GO:0035116(embryonic hindlimb morphogenesis);GO:0035904(aorta development);GO:0035909(aorta morphogenesis);GO:0036302(atrioventricular canal development);GO:0040018(positive regulation of multicellular organism growth);GO:0042048(olfactory behavior);GO:0042471(ear morphogenesis);GO:0042472(inner ear morphogenesis);GO:0043010(camera-type eye development);GO:0043584(nose development);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0048752(semicircular canal morphogenesis);GO:0048771(tissue remodeling);GO:0048844(artery morphogenesis);GO:0050767(regulation of neurogenesis);GO:0060123(regulation of growth hormone secretion);GO:0060384(innervation);GO:0060411(cardiac septum morphogenesis);GO:0060429(epithelium development)","NA","NA","NA","chromodomain helicase DNA binding protein 7 [Source:HGNC Symbol;Acc:HGNC:20626]",{"v":3.034127,"d":"3.03"},{"v":0.468824,"d":"0.47"},{"v":6.47178258792212,"d":"6.47"},{"v":2.69416314290463,"d":"2.69"},{"v":0.000327364269559155,"d":"0.00"},{"v":0.00958266888466945,"d":"0.01"},"up","yes"]
[105414,0,"chr19","+",54200809,54206847,"ENST00000484121",4,897,"MSTRG.8410","RPS9","GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0006412(translation);GO:0030529(intracellular ribonucleoprotein complex);GO:0005622(intracellular);GO:0003735(structural constituent of ribosome);GO:0005840(ribosome);GO:0015935(small ribosomal subunit);GO:0005515(protein binding);GO:0022627(cytosolic small ribosomal subunit);GO:0019843(rRNA binding);GO:0005730(nucleolus);GO:0005925(focal adhesion);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0008284(positive regulation of cell proliferation);GO:0006413(translational initiation);GO:0006364(rRNA processing);GO:0000184(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay);GO:0019083(viral transcription);GO:0006614(SRP-dependent cotranslational protein targeting to membrane);GO:0045182(translation regulator activity);GO:0045903(positive regulation of translational fidelity)","03010(Ribosome)","NA","NA","ribosomal protein S9 [Source:HGNC Symbol;Acc:HGNC:10442]",{"v":6.245683,"d":"6.25"},{"v":30.599388,"d":"30.60"},{"v":0.204111369809095,"d":"0.20"},{"v":-2.29257154646906,"d":"-2.29"},{"v":3.28396372083367E-4,"d":"0.00"},{"v":0.00959868155212064,"d":"0.01"},"down","yes"]
[10622,0,"chr1","-",150646225,150697024,"ENST00000271732",5,2999,"MSTRG.923","GOLPH3L","GO:0016020(membrane);GO:0005794(Golgi apparatus);GO:0005515(protein binding);GO:0000139(Golgi membrane);GO:0008289(lipid binding);GO:0032580(Golgi cisterna membrane);GO:0005829(cytosol);GO:0070273(phosphatidylinositol-4-phosphate binding);GO:0005802(trans-Golgi network);GO:0043001(Golgi to plasma membrane protein transport);GO:0050714(positive regulation of protein secretion);GO:0006890(retrograde vesicle-mediated transport, Golgi to ER);GO:0007030(Golgi organization);GO:0032588(trans-Golgi network membrane);GO:0048194(Golgi vesicle budding);GO:0031985(Golgi cisterna)","NA","NA","NA","golgi phosphoprotein 3 like [Source:HGNC Symbol;Acc:HGNC:24882]",{"v":0.713217,"d":"0.71"},{"v":3.562009,"d":"3.56"},{"v":0.200228859612651,"d":"0.20"},{"v":-2.32027816557173,"d":"-2.32"},{"v":0.000331548664603948,"d":"0.00"},{"v":0.0096765265120692,"d":"0.01"},"down","yes"]
[98659,0,"chr19","+",18571858,18573790,"ENST00000598814",2,550,"MSTRG.8003","UBA52","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005783(endoplasmic reticulum);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0030529(intracellular ribonucleoprotein complex);GO:0005765(lysosomal membrane);GO:0003735(structural constituent of ribosome);GO:0006412(translation);GO:0005840(ribosome);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0044322(endoplasmic reticulum quality control compartment);GO:0005615(extracellular space);GO:0038095(Fc-epsilon receptor signaling pathway);GO:0016567(protein ubiquitination);GO:0005789(endoplasmic reticulum membrane);GO:0006977(DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest);GO:0070062(extracellular exosome);GO:0034220(ion transmembrane transport);GO:0044267(cellular protein metabolic process);GO:0061024(membrane organization);GO:0016197(endosomal transport);GO:0019058(viral life cycle);GO:0075733(intracellular transport of virus);GO:0010008(endosome membrane);GO:0043657(host cell);GO:0000165(MAPK cascade);GO:0000209(protein polyubiquitination);GO:0002223(stimulatory C-type lectin receptor signaling pathway);GO:0010972(negative regulation of G2/M transition of mitotic cell cycle);GO:0016579(protein deubiquitination);GO:0031145(anaphase-promoting complex-dependent catabolic process);GO:0031146(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process);GO:0033209(tumor necrosis factor-mediated signaling pathway);GO:0038061(NIK/NF-kappaB signaling);GO:0043161(proteasome-mediated ubiquitin-dependent protein catabolic process);GO:0043488(regulation of mRNA stability);GO:0050852(T cell receptor signaling pathway);GO:0051437(positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition);GO:0055085(transmembrane transport);GO:0060071(Wnt signaling pathway, planar cell polarity pathway);GO:0061418(regulation of transcription from RNA polymerase II promoter in response to hypoxia);GO:0090090(negative regulation of canonical Wnt signaling pathway);GO:0090263(positive regulation of canonical Wnt signaling pathway);GO:1902036(regulation of hematopoietic stem cell differentiation);GO:0045087(innate immune response);GO:0000086(G2/M transition of mitotic cell cycle);GO:0036297(interstrand cross-link repair);GO:0006457(protein folding);GO:0002755(MyD88-dependent toll-like receptor signaling pathway);GO:0002756(MyD88-independent toll-like receptor signaling pathway);GO:0007249(I-kappaB kinase/NF-kappaB signaling);GO:0035666(TRIF-dependent toll-like receptor signaling pathway);GO:0051436(negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle);GO:1904380(endoplasmic reticulum mannose trimming);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:1901796(regulation of signal transduction by p53 class mediator);GO:0031982(vesicle);GO:0006413(translational initiation);GO:0006464(cellular protein modification process);GO:0030666(endocytic vesicle membrane);GO:0005741(mitochondrial outer membrane);GO:0006364(rRNA processing);GO:0007219(Notch signaling pathway);GO:0016055(Wnt signaling pathway);GO:0042787(protein ubiquitination involved in ubiquitin-dependent protein catabolic process);GO:0038128(ERBB2 signaling pathway);GO:0007254(JNK cascade);GO:0043065(positive regulation of apoptotic process);GO:0010803(regulation of tumor necrosis factor-mediated signaling pathway);GO:0043066(negative regulation of apoptotic process);GO:0043123(positive regulation of I-kappaB kinase/NF-kappaB signaling);GO:0051092(positive regulation of NF-kappaB transcription factor activity);GO:0051403(stress-activated MAPK cascade);GO:0070423(nucleotide-binding oligomerization domain containing signaling pathway);GO:0019985(translesion synthesis);GO:0032480(negative regulation of type I interferon production);GO:0042059(negative regulation of epidermal growth factor receptor signaling pathway);GO:0030512(negative regulation of transforming growth factor beta receptor signaling pathway);GO:0000184(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay);GO:0005978(glycogen biosynthetic process);GO:0019083(viral transcription);GO:0006283(transcription-coupled nucleotide-excision repair);GO:0008543(fibroblast growth factor receptor signaling pathway);GO:0000187(activation of MAPK activity);GO:0016236(macroautophagy);GO:0042276(error-prone translesion synthesis);GO:0035635(entry of bacterium into host cell);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0006614(SRP-dependent cotranslational protein targeting to membrane);GO:0042769(DNA damage response, detection of DNA damage);GO:0007179(transforming growth factor beta receptor signaling pathway);GO:0006879(cellular iron ion homeostasis);GO:0006296(nucleotide-excision repair, DNA incision, 5'-to lesion);GO:0033683(nucleotide-excision repair, DNA incision);GO:0070911(global genome nucleotide-excision repair);GO:0000715(nucleotide-excision repair, DNA damage recognition);GO:0000717(nucleotide-excision repair, DNA duplex unwinding);GO:0006294(nucleotide-excision repair, preincision complex assembly);GO:0006297(nucleotide-excision repair, DNA gap filling);GO:0019068(virion assembly);GO:0032479(regulation of type I interferon production);GO:0045742(positive regulation of epidermal growth factor receptor signaling pathway);GO:0060544(regulation of necroptotic process);GO:0070987(error-free translesion synthesis)","03010(Ribosome)","NA","NA","ubiquitin A-52 residue ribosomal protein fusion product 1 [Source:HGNC Symbol;Acc:HGNC:12458]",{"v":1.595616,"d":"1.60"},{"v":8.335035,"d":"8.34"},{"v":0.191434829007917,"d":"0.19"},{"v":-2.38507476210741,"d":"-2.39"},{"v":0.000332914855260654,"d":"0.00"},{"v":0.00970209006759621,"d":"0.01"},"down","yes"]
[146123,0,"chr4","-",15605006,15655341,"ENST00000511441",12,2951,"MSTRG.11545","FBXL5","GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0016567(protein ubiquitination);GO:0005515(protein binding);GO:0048471(perinuclear region of cytoplasm);GO:0005506(iron ion binding);GO:0005829(cytosol);GO:0000209(protein polyubiquitination);GO:0043687(post-translational protein modification);GO:0004842(ubiquitin-protein transferase activity);GO:0000151(ubiquitin ligase complex);GO:0006879(cellular iron ion homeostasis);GO:0055072(iron ion homeostasis);GO:0019005(SCF ubiquitin ligase complex);GO:0031146(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process);GO:1903364(positive regulation of cellular protein catabolic process)","NA","NA","NA","F-box and leucine rich repeat protein 5 [Source:HGNC Symbol;Acc:HGNC:13602]",{"v":2.051705,"d":"2.05"},{"v":10.003073,"d":"10.00"},{"v":0.205107470474323,"d":"0.21"},{"v":-2.28554805592194,"d":"-2.29"},{"v":0.000334286601290912,"d":"0.00"},{"v":0.00972774009756554,"d":"0.01"},"down","yes"]
[93115,0,"chr18","+",62523667,62586729,"ENST00000585873",15,5652,"ENSG00000141664","ZCCHC2","GO:0003676(nucleic acid binding);GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0035091(phosphatidylinositol binding);GO:0005737(cytoplasm)","NA","NA","NA","zinc finger CCHC-type containing 2 [Source:HGNC Symbol;Acc:HGNC:22916]",{"v":1.786541,"d":"1.79"},{"v":0.268862,"d":"0.27"},{"v":6.64482522632429,"d":"6.64"},{"v":2.73223125391361,"d":"2.73"},{"v":0.000336190012412241,"d":"0.00"},{"v":0.009768763532472,"d":"0.01"},"up","yes"]
[79794,0,"chr17","-",16029157,16215549,"ENST00000268712",46,10720,"MSTRG.6470","NCOR1","GO:0005634(nucleus);GO:0016020(membrane);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0016569(covalent chromatin modification);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0003714(transcription corepressor activity);GO:0000118(histone deacetylase complex);GO:0005876(spindle microtubule);GO:0046329(negative regulation of JNK cascade);GO:0000790(nuclear chromatin);GO:0006366(transcription from RNA polymerase II promoter);GO:0007623(circadian rhythm);GO:0044212(transcription regulatory region DNA binding);GO:0001102(RNA polymerase II activating transcription factor binding);GO:0042826(histone deacetylase binding);GO:0019216(regulation of lipid metabolic process);GO:0051225(spindle assembly);GO:0017053(transcriptional repressor complex);GO:0035257(nuclear hormone receptor binding);GO:0016580(Sin3 complex);GO:0016922(ligand-dependent nuclear receptor binding);GO:0046966(thyroid hormone receptor binding);GO:0072362(regulation of glycolytic process by negative regulation of transcription from RNA polymerase II promoter);GO:0072368(regulation of lipid transport by negative regulation of transcription from RNA polymerase II promoter);GO:1903799(negative regulation of production of miRNAs involved in gene silencing by miRNA);GO:2000191(regulation of fatty acid transport)","04919(Thyroid hormone signaling pathway);05202(Transcriptional misregulation in cancers);01522(Endocrine resistance)","K04650","NA","nuclear receptor corepressor 1 [Source:HGNC Symbol;Acc:HGNC:7672]",{"v":2.179882,"d":"2.18"},{"v":0.336237,"d":"0.34"},{"v":6.48317109657771,"d":"6.48"},{"v":2.69669964740986,"d":"2.70"},{"v":0.000336758016571229,"d":"0.00"},{"v":0.00977092028139514,"d":"0.01"},"up","yes"]
[167007,0,"chr6","+",63646526,63714509,"ENST00000393387",15,6947,"MSTRG.13104","PHF3","GO:0046872(metal ion binding);GO:0006351(transcription, DNA-templated);GO:0007275(multicellular organism development);GO:0003674(molecular_function);GO:0005575(cellular_component)","NA","NA","NA","PHD finger protein 3 [Source:HGNC Symbol;Acc:HGNC:8921]",{"v":0.348634,"d":"0.35"},{"v":1.723703,"d":"1.72"},{"v":0.202258741790204,"d":"0.20"},{"v":-2.30572603641096,"d":"-2.31"},{"v":0.0003416334645744,"d":"0.00"},{"v":0.00989786675988027,"d":"0.01"},"down","yes"]
[149261,0,"chr4","+",88605794,88708541,"ENST00000264345",24,4764,"MSTRG.11726","HERC3","GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0016740(transferase activity);GO:0016567(protein ubiquitination);GO:0004842(ubiquitin-protein transferase activity);GO:0031410(cytoplasmic vesicle);GO:0061630(ubiquitin protein ligase activity)","04120(Ubiquitin mediated proteolysis)","NA","NA","HECT and RLD domain containing E3 ubiquitin protein ligase 3 [Source:HGNC Symbol;Acc:HGNC:4876]",{"v":0.180692,"d":"0.18"},{"v":0.94538,"d":"0.95"},{"v":0.191131608453743,"d":"0.19"},{"v":-2.38736171066625,"d":"-2.39"},{"v":0.000342228210251324,"d":"0.00"},{"v":0.00990060208253392,"d":"0.01"},"down","yes"]
[148112,0,"chr4","-",73075686,73258798,"ENST00000330838",33,7734,"ENSG00000132466","ANKRD17","GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0031965(nuclear membrane);GO:0002376(immune system process);GO:0045087(innate immune response);GO:0042742(defense response to bacterium);GO:0005515(protein binding);GO:0003682(chromatin binding);GO:0016032(viral process);GO:0043123(positive regulation of I-kappaB kinase/NF-kappaB signaling);GO:0000785(chromatin);GO:1900087(positive regulation of G1/S transition of mitotic cell cycle);GO:0045787(positive regulation of cell cycle);GO:0001955(blood vessel maturation);GO:0006275(regulation of DNA replication);GO:0051151(negative regulation of smooth muscle cell differentiation);GO:1900245(positive regulation of MDA-5 signaling pathway);GO:1900246(positive regulation of RIG-I signaling pathway)","NA","NA","NA","ankyrin repeat domain 17 [Source:HGNC Symbol;Acc:HGNC:23575]",{"v":4.920686,"d":"4.92"},{"v":0.767941,"d":"0.77"},{"v":6.40763548241336,"d":"6.41"},{"v":2.67979207804116,"d":"2.68"},{"v":3.44787766369915E-4,"d":"0.00"},{"v":0.00996008805974874,"d":"0.01"},"up","yes"]
[62795,0,"chr15","-",55359018,55408052,"ENST00000569205",8,2970,"MSTRG.5103","CCPG1","GO:2001106(regulation of Rho guanyl-nucleotide exchange factor activity);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0007049(cell cycle);GO:0003674(molecular_function);GO:0008284(positive regulation of cell proliferation);GO:0005515(protein binding);GO:0045787(positive regulation of cell cycle);GO:0045944(positive regulation of transcription from RNA polymerase II promoter)","NA","NA","NA","cell cycle progression 1 [Source:HGNC Symbol;Acc:HGNC:24227]",{"v":2.846451,"d":"2.85"},{"v":0.426652,"d":"0.43"},{"v":6.67159886746107,"d":"6.67"},{"v":2.73803254877629,"d":"2.74"},{"v":0.000346291390774713,"d":"0.00"},{"v":0.00996865219169282,"d":"0.01"},"up","yes"]
[36644,0,"chr11","+",125592867,125620888,"ENST00000531491",17,2160,"MSTRG.2953","STT3A","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0006486(protein glycosylation);GO:0004576(oligosaccharyl transferase activity);GO:0046872(metal ion binding);GO:0016740(transferase activity);GO:0016757(transferase activity, transferring glycosyl groups);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005515(protein binding);GO:0018279(protein N-linked glycosylation via asparagine);GO:0004579(dolichyl-diphosphooligosaccharide-protein glycotransferase activity);GO:0008250(oligosaccharyltransferase complex);GO:0043686(co-translational protein modification);GO:0043687(post-translational protein modification)","00510(N-Glycan biosynthesis);04141(Protein processing in endoplasmic reticulum)","K07151","EC:2.4.99.18","STT3A, catalytic subunit of the oligosaccharyltransferase complex [Source:HGNC Symbol;Acc:HGNC:6172]",{"v":0.549762,"d":"0.55"},{"v":2.819875,"d":"2.82"},{"v":0.194959705660712,"d":"0.19"},{"v":-2.35875211681232,"d":"-2.36"},{"v":0.000346412892491088,"d":"0.00"},{"v":0.00996865219169282,"d":"0.01"},"down","yes"]
[94397,0,"chr19","-",1573596,1592801,"ENST00000156825",7,5518,"MSTRG.7612","MBD3","GO:0005634(nucleus);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0016575(histone deacetylation);GO:0003677(DNA binding);GO:0000790(nuclear chromatin);GO:0005694(chromosome);GO:0005515(protein binding);GO:0005654(nucleoplasm);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0006346(methylation-dependent chromatin silencing);GO:0043234(protein complex);GO:1901796(regulation of signal transduction by p53 class mediator);GO:0004407(histone deacetylase activity);GO:0008327(methyl-CpG binding);GO:0031492(nucleosomal DNA binding);GO:0043044(ATP-dependent chromatin remodeling);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:0000980(RNA polymerase II distal enhancer sequence-specific DNA binding);GO:0016581(NuRD complex);GO:0003682(chromatin binding);GO:0001701(in utero embryonic development);GO:0007420(brain development);GO:0007507(heart development);GO:0007568(aging);GO:0009888(tissue development);GO:0014070(response to organic cyclic compound);GO:0016573(histone acetylation);GO:0031667(response to nutrient levels);GO:0032355(response to estradiol);GO:0044030(regulation of DNA methylation);GO:0048568(embryonic organ development);GO:0000785(chromatin);GO:0000792(heterochromatin);GO:0005737(cytoplasm)","NA","NA","NA","methyl-CpG binding domain protein 3 [Source:HGNC Symbol;Acc:HGNC:6918]",{"v":2.567828,"d":"2.57"},{"v":0.392024,"d":"0.39"},{"v":6.55018060118768,"d":"6.55"},{"v":2.71153468509984,"d":"2.71"},{"v":0.000346965226700826,"d":"0.00"},{"v":0.00996865219169282,"d":"0.01"},"up","yes"]
[58985,"j","chr14","+",103121459,103137439,"MSTRG.4696.4",13,4848,"MSTRG.4696","TNFAIP2","NA","NA","NA","NA","NA",{"v":46.042736,"d":"46.04"},{"v":7.24806,"d":"7.25"},{"v":6.35242202741147,"d":"6.35"},{"v":2.66730676207601,"d":"2.67"},{"v":0.000347099320804344,"d":"0.00"},{"v":0.00996865219169282,"d":"0.01"},"up","yes"]
[93697,0,"chr18","+",79400336,79529323,"ENST00000329101",10,4595,"MSTRG.7558","NFATC1","GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0005737(cytoplasm);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0005515(protein binding);GO:0016604(nuclear body);GO:0045893(positive regulation of transcription, DNA-templated);GO:0038095(Fc-epsilon receptor signaling pathway);GO:0005829(cytosol);GO:0000790(nuclear chromatin);GO:0006366(transcription from RNA polymerase II promoter);GO:0001085(RNA polymerase II transcription factor binding);GO:0000980(RNA polymerase II distal enhancer sequence-specific DNA binding);GO:0003705(transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding);GO:0035556(intracellular signal transduction);GO:0007223(Wnt signaling pathway, calcium modulating pathway);GO:0005528(FK506 binding);GO:0001205(transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding);GO:0048273(mitogen-activated protein kinase p38 binding);GO:0030178(negative regulation of Wnt signaling pathway);GO:0033173(calcineurin-NFAT signaling cascade);GO:0000977(RNA polymerase II regulatory region sequence-specific DNA binding);GO:0001225(RNA polymerase II transcription coactivator binding)","04010(MAPK signaling pathway);04310(Wnt signaling pathway);04024(cAMP signaling pathway);04022(cGMP - PKG signaling pathway);04218(Cellular senescence);04650(Natural killer cell mediated cytotoxicity);04660(T cell receptor signaling pathway);04658(Th1 and Th2 cell differentiation);04659(Th17 cell differentiation);04662(B cell receptor signaling pathway);04921(Oxytocin signaling pathway);04380(Osteoclast differentiation);05321(Inflammatiory bowel disease (IBD));04933(AGE-RAGE signaling pathway in diabetic complications);05166(HTLV-I infection);05161(Hepatitis B);05167(Kaposi's sarcoma-associated herpesvirus infection)","K04446","NA","nuclear factor of activated T-cells 1 [Source:HGNC Symbol;Acc:HGNC:7775]",{"v":5.059363,"d":"5.06"},{"v":0.784,"d":"0.78"},{"v":6.45326913265306,"d":"6.45"},{"v":2.6900301941242,"d":"2.69"},{"v":3.48524142689018E-4,"d":"0.00"},{"v":0.00997570225079475,"d":"0.01"},"up","yes"]
[128795,0,"chr22","+",20507610,20587619,"ENST00000263205",18,3351,"MSTRG.10158","MED15","GO:0005634(nucleus);GO:0001104(RNA polymerase II transcription cofactor activity);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0016592(mediator complex);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0005515(protein binding);GO:0005654(nucleoplasm);GO:0006367(transcription initiation from RNA polymerase II promoter)","NA","NA","NA","mediator complex subunit 15 [Source:HGNC Symbol;Acc:HGNC:14248]",{"v":18.172197,"d":"18.17"},{"v":2.850507,"d":"2.85"},{"v":6.3750753813269,"d":"6.38"},{"v":2.6724424010497,"d":"2.67"},{"v":0.000348622148324889,"d":"0.00"},{"v":0.00997570225079475,"d":"0.01"},"up","yes"]
[179585,0,"chr7","+",142855124,142871094,"ENST00000616380",18,4409,"ENSG00000106123","EPHB6","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0005003(ephrin receptor activity);GO:0007169(transmembrane receptor protein tyrosine kinase signaling pathway);GO:0005887(integral component of plasma membrane);GO:0048013(ephrin receptor signaling pathway);GO:0001806(type IV hypersensitivity);GO:0002456(T cell mediated immunity);GO:0032092(positive regulation of protein binding);GO:0050663(cytokine secretion);GO:0050798(activated T cell proliferation);GO:2000525(positive regulation of T cell costimulation);GO:0009986(cell surface)","04360(Axon guidance)","NA","NA","EPH receptor B6 [Source:HGNC Symbol;Acc:HGNC:3396]",{"v":0.43784,"d":"0.44"},{"v":2.180915,"d":"2.18"},{"v":0.200759772847635,"d":"0.20"},{"v":-2.31645787603323,"d":"-2.32"},{"v":0.000348857184028197,"d":"0.00"},{"v":0.00997570225079475,"d":"0.01"},"down","yes"]
[166082,"j","chr6","+",42928680,42941142,"MSTRG.13045.1",7,4141,"MSTRG.13045","CNPY3","NA","NA","NA","NA","NA",{"v":5.567214,"d":"5.57"},{"v":26.768085,"d":"26.77"},{"v":0.207979539813924,"d":"0.21"},{"v":-2.26548648604437,"d":"-2.27"},{"v":3.51073548369617E-4,"d":"0.00"},{"v":0.0100135750936365,"d":"0.01"},"down","yes"]
[50089,0,"chr13","-",45338185,45341086,"ENST00000309246",5,1008,"MSTRG.3983","TPT1","GO:0003723(RNA binding);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005515(protein binding);GO:0006816(calcium ion transport);GO:0005509(calcium ion binding);GO:0070062(extracellular exosome);GO:0008017(microtubule binding);GO:0009615(response to virus);GO:0030154(cell differentiation);GO:0042981(regulation of apoptotic process);GO:0043066(negative regulation of apoptotic process);GO:0005615(extracellular space);GO:0005634(nucleus);GO:0006874(cellular calcium ion homeostasis);GO:0045298(tubulin complex);GO:1902230(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage);GO:0005771(multivesicular body)","NA","NA","NA","tumor protein, translationally-controlled 1 [Source:HGNC Symbol;Acc:HGNC:12022]",{"v":1.243923,"d":"1.24"},{"v":6.290441,"d":"6.29"},{"v":0.197748138802987,"d":"0.20"},{"v":-2.33826397870933,"d":"-2.34"},{"v":0.000351645104901938,"d":"0.00"},{"v":0.0100135750936365,"d":"0.01"},"down","yes"]
[196646,0,"chrX","+",44873511,45112602,"ENST00000377967",29,5438,"MSTRG.15250","KDM6A","GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0016569(covalent chromatin modification);GO:0051213(dioxygenase activity);GO:0071558(histone demethylase activity (H3-K27 specific));GO:0010468(regulation of gene expression);GO:0071557(histone H3-K27 demethylation);GO:0005654(nucleoplasm);GO:0035097(histone methyltransferase complex);GO:0032452(histone demethylase activity);GO:0051568(histone H3-K4 methylation);GO:0044666(MLL3/4 complex);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:0031490(chromatin DNA binding);GO:0042802(identical protein binding);GO:0001701(in utero embryonic development);GO:0001843(neural tube closure);GO:0003007(heart morphogenesis);GO:0003016(respiratory system process);GO:0007507(heart development);GO:0010628(positive regulation of gene expression);GO:0021915(neural tube development);GO:0032525(somite rostral/caudal axis specification);GO:0035264(multicellular organism growth);GO:0048333(mesodermal cell differentiation);GO:0048568(embryonic organ development);GO:0048570(notochord morphogenesis);GO:0060070(canonical Wnt signaling pathway);GO:0072358(cardiovascular system development)","05202(Transcriptional misregulation in cancers)","K11447","EC:1.14.11.-","lysine demethylase 6A [Source:HGNC Symbol;Acc:HGNC:12637]",{"v":4.411554,"d":"4.41"},{"v":0.684828,"d":"0.68"},{"v":6.44184233121309,"d":"6.44"},{"v":2.68747335014006,"d":"2.69"},{"v":0.000351699751873732,"d":"0.00"},{"v":0.0100135750936365,"d":"0.01"},"up","yes"]
[87707,0,"chr17","+",74737217,74747300,"ENST00000392613",9,2617,"MSTRG.7180","RAB37","GO:0005525(GTP binding);GO:0003924(GTPase activity);GO:0006810(transport);GO:0015031(protein transport);GO:0000166(nucleotide binding);GO:0005515(protein binding);GO:0031410(cytoplasmic vesicle);GO:0005886(plasma membrane);GO:0005768(endosome);GO:0009306(protein secretion);GO:0043312(neutrophil degranulation);GO:0035579(specific granule membrane);GO:0035577(azurophil granule membrane);GO:0005793(endoplasmic reticulum-Golgi intermediate compartment);GO:0008021(synaptic vesicle);GO:0072659(protein localization to plasma membrane);GO:0030667(secretory granule membrane);GO:0006904(vesicle docking involved in exocytosis);GO:0017157(regulation of exocytosis)","NA","NA","NA","RAB37, member RAS oncogene family [Source:HGNC Symbol;Acc:HGNC:30268]",{"v":22.186321,"d":"22.19"},{"v":3.479932,"d":"3.48"},{"v":6.37550417651839,"d":"6.38"},{"v":2.6725394351796,"d":"2.67"},{"v":0.000352475133805415,"d":"0.00"},{"v":0.0100212326835367,"d":"0.01"},"up","yes"]
[9842,0,"chr1","+",120805418,120840619,"ENST00000617913",21,2931,"ENSG00000273136","NBPF26","GO:0005509(calcium ion binding);GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process)","NA","NA","NA","NBPF member 26 [Source:HGNC Symbol;Acc:HGNC:49571]",{"v":2.87239,"d":"2.87"},{"v":0.432928,"d":"0.43"},{"v":6.63479839603814,"d":"6.63"},{"v":2.73005262875223,"d":"2.73"},{"v":0.000354554609461967,"d":"0.00"},{"v":0.0100658918393593,"d":"0.01"},"up","yes"]
[14011,0,"chr1","-",179859030,179877799,"ENST00000482587",3,7067,"ENSG00000169905","TOR1AIP2","GO:0005634(nucleus);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0031965(nuclear membrane);GO:0007029(endoplasmic reticulum organization);GO:0032781(positive regulation of ATPase activity);GO:0001671(ATPase activator activity);GO:0051117(ATPase binding);GO:0090435(protein localization to nuclear envelope);GO:0005515(protein binding)","NA","NA","NA","torsin 1A interacting protein 2 [Source:HGNC Symbol;Acc:HGNC:24055]",{"v":0.153078,"d":"0.15"},{"v":0.784284,"d":"0.78"},{"v":0.195181847392016,"d":"0.20"},{"v":-2.35710921153216,"d":"-2.36"},{"v":0.000356230090135583,"d":"0.00"},{"v":0.0100989699478552,"d":"0.01"},"down","yes"]
[70035,0,"chr16","-",15865720,15888615,"ENST00000255759",5,2275,"ENSG00000133393","FOPNL","GO:0005737(cytoplasm);GO:0005634(nucleus);GO:0031514(motile cilium);GO:0005813(centrosome);GO:0005856(cytoskeleton);GO:0042995(cell projection);GO:0005815(microtubule organizing center);GO:0034453(microtubule anchoring);GO:0060271(cilium assembly);GO:0005929(cilium);GO:0030030(cell projection organization);GO:0005814(centriole);GO:0036064(ciliary basal body);GO:0034451(centriolar satellite)","NA","NA","NA","FGFR1OP N-terminal like [Source:HGNC Symbol;Acc:HGNC:26435]",{"v":6.368866,"d":"6.37"},{"v":0.982255,"d":"0.98"},{"v":6.48392321749444,"d":"6.48"},{"v":2.69686700658712,"d":"2.70"},{"v":0.000358121123168934,"d":"0.00"},{"v":0.0101380554867909,"d":"0.01"},"up","yes"]
[173564,0,"chr7","+",44044717,44061716,"ENST00000494774",13,2117,"MSTRG.13625","DBNL","GO:0005737(cytoplasm);GO:0006810(transport);GO:0016020(membrane);GO:0003779(actin binding);GO:0051015(actin filament binding);GO:0005794(Golgi apparatus);GO:0005622(intracellular);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0005856(cytoskeleton);GO:0042995(cell projection);GO:0005515(protein binding);GO:0000139(Golgi membrane);GO:0030054(cell junction);GO:0045202(synapse);GO:0031410(cytoplasmic vesicle);GO:0002376(immune system process);GO:0002250(adaptive immune response);GO:0005576(extracellular region);GO:0097178(ruffle assembly);GO:0006898(receptor-mediated endocytosis);GO:0007416(synapse assembly);GO:0005768(endosome);GO:0045296(cadherin binding);GO:0006897(endocytosis);GO:0048812(neuron projection morphogenesis);GO:0030027(lamellipodium);GO:0070062(extracellular exosome);GO:0071800(podosome assembly);GO:0002102(podosome);GO:0005938(cell cortex);GO:0005769(early endosome);GO:0043312(neutrophil degranulation);GO:0001726(ruffle);GO:0030665(clathrin-coated vesicle membrane);GO:0034774(secretory granule lumen);GO:1904813(ficolin-1-rich granule lumen);GO:1904724(tertiary granule lumen);GO:0008047(enzyme activator activity);GO:0007257(activation of JUN kinase activity);GO:0016601(Rac protein signal transduction);GO:0008022(protein C-terminus binding);GO:0019904(protein domain specific binding);GO:0014069(postsynaptic density);GO:0030425(dendrite)","NA","NA","NA","drebrin like [Source:HGNC Symbol;Acc:HGNC:2696]",{"v":20.452299,"d":"20.45"},{"v":3.209809,"d":"3.21"},{"v":6.37181184300997,"d":"6.37"},{"v":2.67170366529946,"d":"2.67"},{"v":0.000360102868179377,"d":"0.00"},{"v":0.0101795936507621,"d":"0.01"},"up","yes"]
[88114,0,"chr17","+",75633434,75641404,"ENST00000375215",3,1546,"MSTRG.7220","SMIM5","GO:0016020(membrane);GO:0016021(integral component of membrane)","NA","NA","NA","small integral membrane protein 5 [Source:HGNC Symbol;Acc:HGNC:40030]",{"v":1.745115,"d":"1.75"},{"v":8.542217,"d":"8.54"},{"v":0.204292983893994,"d":"0.20"},{"v":-2.29128843695011,"d":"-2.29"},{"v":3.61616018949424E-4,"d":"0.00"},{"v":0.0102077857103726,"d":"0.01"},"down","yes"]
[11441,"j","chr1","-",154582067,154608198,"MSTRG.1019.5",15,6534,"MSTRG.1019","ADAR","NA","NA","NA","NA","NA",{"v":25.925663,"d":"25.93"},{"v":4.111301,"d":"4.11"},{"v":6.30595108458369,"d":"6.31"},{"v":2.65671397904404,"d":"2.66"},{"v":0.000367082365376937,"d":"0.00"},{"v":0.0103473302650696,"d":"0.01"},"up","yes"]
[117944,0,"chr2","+",201116104,201176687,"ENST00000309955",10,14672,"MSTRG.9352","CFLAR","GO:0005737(cytoplasm);GO:0042981(regulation of apoptotic process);GO:0043085(positive regulation of catalytic activity);GO:0005515(protein binding);GO:0008234(cysteine-type peptidase activity);GO:0006508(proteolysis);GO:0006915(apoptotic process);GO:0004197(cysteine-type endopeptidase activity);GO:0002020(protease binding);GO:0005123(death receptor binding);GO:0032403(protein complex binding);GO:0001666(response to hypoxia);GO:0010667(negative regulation of cardiac muscle cell apoptotic process);GO:0010976(positive regulation of neuron projection development);GO:0032869(cellular response to insulin stimulus);GO:0033574(response to testosterone);GO:0043066(negative regulation of apoptotic process);GO:0070374(positive regulation of ERK1 and ERK2 cascade);GO:0071364(cellular response to epidermal growth factor stimulus);GO:0071392(cellular response to estradiol stimulus);GO:0071456(cellular response to hypoxia);GO:0071549(cellular response to dexamethasone stimulus);GO:0071732(cellular response to nitric oxide);GO:0072126(positive regulation of glomerular mesangial cell proliferation);GO:1903055(positive regulation of extracellular matrix organization);GO:1903427(negative regulation of reactive oxygen species biosynthetic process);GO:1903845(negative regulation of cellular response to transforming growth factor beta stimulus);GO:1903944(negative regulation of hepatocyte apoptotic process);GO:1904036(negative regulation of epithelial cell apoptotic process);GO:2000347(positive regulation of hepatocyte proliferation);GO:0031264(death-inducing signaling complex);GO:0031265(CD95 death-inducing signaling complex);GO:0045121(membrane raft);GO:0005829(cytosol);GO:0016032(viral process);GO:0043123(positive regulation of I-kappaB kinase/NF-kappaB signaling);GO:1902041(regulation of extrinsic apoptotic signaling pathway via death domain receptors);GO:1902042(negative regulation of extrinsic apoptotic signaling pathway via death domain receptors);GO:0051092(positive regulation of NF-kappaB transcription factor activity);GO:0008047(enzyme activator activity);GO:0097200(cysteine-type endopeptidase activity involved in execution phase of apoptosis);GO:0007519(skeletal muscle tissue development);GO:0014732(skeletal muscle atrophy);GO:0014842(regulation of skeletal muscle satellite cell proliferation);GO:0014866(skeletal myofibril assembly);GO:0043403(skeletal muscle tissue regeneration);GO:0060544(regulation of necroptotic process);GO:0097194(execution phase of apoptosis);GO:1901740(negative regulation of myoblast fusion);GO:2001237(negative regulation of extrinsic apoptotic signaling pathway);GO:0097342(ripoptosome)","04064(NF-kappa B signaling pathway);04668(TNF signaling pathway);04140(Autophagy - animal);04210(Apoptosis);04217(Necroptosis);05142(Chagas disease (American trypanosomiasis))","K04724","NA","CASP8 and FADD like apoptosis regulator [Source:HGNC Symbol;Acc:HGNC:1876]",{"v":12.455637,"d":"12.46"},{"v":1.978617,"d":"1.98"},{"v":6.29512280547473,"d":"6.30"},{"v":2.65423452236387,"d":"2.65"},{"v":3.70572823484934E-4,"d":"0.00"},{"v":0.010409179110154,"d":"0.01"},"up","yes"]
[587,"j","chr1","-",1751232,1780502,"MSTRG.65.1",13,3399,"MSTRG.65","NADK","NA","NA","NA","NA","NA",{"v":51.916004,"d":"51.92"},{"v":8.244135,"d":"8.24"},{"v":6.29732579585366,"d":"6.30"},{"v":2.65473930795845,"d":"2.65"},{"v":3.70822617886864E-4,"d":"0.00"},{"v":0.010409179110154,"d":"0.01"},"up","yes"]
[175960,0,"chr7","+",90709531,91210585,"ENST00000406263",14,5163,"ENSG00000058091","CDK14","GO:0004672(protein kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0005634(nucleus);GO:0005829(cytosol);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0000166(nucleotide binding);GO:0004674(protein serine/threonine kinase activity);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0051301(cell division);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0007049(cell cycle);GO:0016055(Wnt signaling pathway);GO:0051726(regulation of cell cycle);GO:0030332(cyclin binding);GO:0000086(G2/M transition of mitotic cell cycle);GO:0004693(cyclin-dependent protein serine/threonine kinase activity);GO:0060828(regulation of canonical Wnt signaling pathway);GO:0000308(cytoplasmic cyclin-dependent protein kinase holoenzyme complex)","05202(Transcriptional misregulation in cancers)","K08821","EC:2.7.11.22","cyclin dependent kinase 14 [Source:HGNC Symbol;Acc:HGNC:8883]",{"v":1.459056,"d":"1.46"},{"v":0.219367,"d":"0.22"},{"v":6.65121007261803,"d":"6.65"},{"v":2.73361683789948,"d":"2.73"},{"v":0.000370854622632835,"d":"0.00"},{"v":0.010409179110154,"d":"0.01"},"up","yes"]
[94221,0,"chr19","+",1269266,1273172,"ENST00000589710",6,1835,"MSTRG.7603","CIRBP","GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005730(nucleolus);GO:0005515(protein binding);GO:0005654(nucleoplasm);GO:0045727(positive regulation of translation);GO:0010494(cytoplasmic stress granule);GO:0009411(response to UV);GO:0003730(mRNA 3'-UTR binding);GO:0034063(stress granule assembly);GO:0030371(translation repressor activity);GO:0048255(mRNA stabilization);GO:0009409(response to cold);GO:0070181(small ribosomal subunit rRNA binding);GO:0017148(negative regulation of translation)","NA","NA","NA","cold inducible RNA binding protein [Source:HGNC Symbol;Acc:HGNC:1982]",{"v":0.476687,"d":"0.48"},{"v":2.46102,"d":"2.46"},{"v":0.193694890736361,"d":"0.19"},{"v":-2.36814219570371,"d":"-2.37"},{"v":0.000372974818291168,"d":"0.00"},{"v":0.0104538607710278,"d":"0.01"},"down","yes"]
[199805,0,"chrX","+",123860027,123913979,"ENST00000371199",7,8591,"ENSG00000101966","XIAP","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0016740(transferase activity);GO:0016567(protein ubiquitination);GO:0005515(protein binding);GO:0006974(cellular response to DNA damage stimulus);GO:0006915(apoptotic process);GO:0016055(Wnt signaling pathway);GO:0004869(cysteine-type endopeptidase inhibitor activity);GO:0030414(peptidase inhibitor activity);GO:0010466(negative regulation of peptidase activity);GO:0042802(identical protein binding);GO:0061630(ubiquitin protein ligase activity);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0031398(positive regulation of protein ubiquitination);GO:0042127(regulation of cell proliferation);GO:0090263(positive regulation of canonical Wnt signaling pathway);GO:0043066(negative regulation of apoptotic process);GO:0004842(ubiquitin-protein transferase activity);GO:0043154(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process);GO:1990001(inhibition of cysteine-type endopeptidase activity involved in apoptotic process);GO:0050727(regulation of inflammatory response);GO:0045088(regulation of innate immune response);GO:0030510(regulation of BMP signaling pathway);GO:0043027(cysteine-type endopeptidase inhibitor activity involved in apoptotic process);GO:0055070(copper ion homeostasis);GO:0070424(regulation of nucleotide-binding oligomerization domain containing signaling pathway);GO:1902530(positive regulation of protein linear polyubiquitination)","04120(Ubiquitin mediated proteolysis);04064(NF-kappa B signaling pathway);04210(Apoptosis);04215(Apoptosis - multiple species);04217(Necroptosis);04510(Focal adhesion);04621(NOD-like receptor signaling pathway);05200(Pathways in cancer);05222(Small cell lung cancer);05166(HTLV-I infection);05145(Toxoplasmosis);01524(Platinum drug resistance)","K04725","EC:2.3.2.27","X-linked inhibitor of apoptosis [Source:HGNC Symbol;Acc:HGNC:592]",{"v":3.04031,"d":"3.04"},{"v":0.477178,"d":"0.48"},{"v":6.37143791205797,"d":"6.37"},{"v":2.67161899799078,"d":"2.67"},{"v":0.000376405520214166,"d":"0.00"},{"v":0.010535095380478,"d":"0.01"},"up","yes"]
[161488,0,"chr5","+",177133079,177300210,"ENST00000354179",24,12195,"ENSG00000165671","NSD1","GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0008168(methyltransferase activity);GO:0016740(transferase activity);GO:0032259(methylation);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0016569(covalent chromatin modification);GO:0005694(chromosome);GO:0008270(zinc ion binding);GO:0018024(histone-lysine N-methyltransferase activity);GO:0046975(histone methyltransferase activity (H3-K36 specific));GO:0045893(positive regulation of transcription, DNA-templated);GO:0034968(histone lysine methylation);GO:0042799(histone methyltransferase activity (H4-K20 specific));GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0003714(transcription corepressor activity);GO:0005654(nucleoplasm);GO:0030331(estrogen receptor binding);GO:0042974(retinoic acid receptor binding);GO:0003682(chromatin binding);GO:0003712(transcription cofactor activity);GO:0050681(androgen receptor binding);GO:0046966(thyroid hormone receptor binding);GO:0046965(retinoid X receptor binding);GO:0016571(histone methylation);GO:0000979(RNA polymerase II core promoter sequence-specific DNA binding);GO:0000414(regulation of histone H3-K36 methylation);GO:0010452(histone H3-K36 methylation);GO:0033135(regulation of peptidyl-serine phosphorylation);GO:0034770(histone H4-K20 methylation);GO:1903025(regulation of RNA polymerase II regulatory region sequence-specific DNA binding)","00310(Lysine degradation)","K15588","EC:2.1.1.43","nuclear receptor binding SET domain protein 1 [Source:HGNC Symbol;Acc:HGNC:14234]",{"v":3.538383,"d":"3.54"},{"v":0.558896,"d":"0.56"},{"v":6.33102222953823,"d":"6.33"},{"v":2.66243846117314,"d":"2.66"},{"v":3.78838585694274E-4,"d":"0.00"},{"v":0.0105882174205061,"d":"0.01"},"up","yes"]
[41010,0,"chr12","-",48688464,48716898,"ENST00000261900",9,6973,"ENSG00000129315","CCNT1","GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0051301(cell division);GO:0005515(protein binding);GO:0007049(cell cycle);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0016032(viral process);GO:0004674(protein serine/threonine kinase activity);GO:0006366(transcription from RNA polymerase II promoter);GO:0006368(transcription elongation from RNA polymerase II promoter);GO:0050434(positive regulation of viral transcription);GO:1900364(negative regulation of mRNA polyadenylation);GO:0003677(DNA binding);GO:0042795(snRNA transcription from RNA polymerase II promoter);GO:0006468(protein phosphorylation);GO:0008134(transcription factor binding);GO:0003682(chromatin binding);GO:0016538(cyclin-dependent protein serine/threonine kinase regulator activity);GO:0017069(snRNA binding);GO:0019901(protein kinase binding);GO:0044212(transcription regulatory region DNA binding);GO:0070063(RNA polymerase binding);GO:0097322(7SK snRNA binding);GO:0000079(regulation of cyclin-dependent protein serine/threonine kinase activity);GO:0043923(positive regulation by host of viral transcription);GO:0045737(positive regulation of cyclin-dependent protein serine/threonine kinase activity);GO:1901409(positive regulation of phosphorylation of RNA polymerase II C-terminal domain);GO:0008024(cyclin/CDK positive transcription elongation factor complex)","05202(Transcriptional misregulation in cancers)","K15188","NA","cyclin T1 [Source:HGNC Symbol;Acc:HGNC:1599]",{"v":0.624777,"d":"0.62"},{"v":3.009567,"d":"3.01"},{"v":0.207596973252298,"d":"0.21"},{"v":-2.26814268541956,"d":"-2.27"},{"v":3.81189135645311E-4,"d":"0.00"},{"v":0.0106307784242814,"d":"0.01"},"down","yes"]
[187985,0,"chr8","-",143579728,143597415,"ENST00000442189",10,2207,"MSTRG.14619","EEF1D","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0006412(translation);GO:0005829(cytosol);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0001650(fibrillar center);GO:0005783(endoplasmic reticulum);GO:0005515(protein binding);GO:0004871(signal transducer activity);GO:0003746(translation elongation factor activity);GO:0006414(translational elongation);GO:0005853(eukaryotic translation elongation factor 1 complex);GO:0007165(signal transduction);GO:0045296(cadherin binding);GO:0043123(positive regulation of I-kappaB kinase/NF-kappaB signaling);GO:0008135(translation factor activity, RNA binding);GO:0071479(cellular response to ionizing radiation)","05168(Herpes simplex infection)","K15410","NA","eukaryotic translation elongation factor 1 delta [Source:HGNC Symbol;Acc:HGNC:3211]",{"v":1.19765,"d":"1.20"},{"v":5.814034,"d":"5.81"},{"v":0.205992947409664,"d":"0.21"},{"v":-2.27933315025206,"d":"-2.28"},{"v":3.81707661959501E-4,"d":"0.00"},{"v":0.0106307784242814,"d":"0.01"},"down","yes"]
[182370,0,"chr8","+",26382898,26413129,"ENST00000380629",6,3610,"MSTRG.14248","BNIP3L","GO:0005634(nucleus);GO:0016607(nuclear speck);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005739(mitochondrion);GO:0005783(endoplasmic reticulum);GO:0042803(protein homodimerization activity);GO:0005515(protein binding);GO:0006915(apoptotic process);GO:0005741(mitochondrial outer membrane);GO:0042802(identical protein binding);GO:0051607(defense response to virus);GO:0043065(positive regulation of apoptotic process);GO:0005740(mitochondrial envelope);GO:0016032(viral process);GO:0043066(negative regulation of apoptotic process);GO:0042981(regulation of apoptotic process);GO:0046982(protein heterodimerization activity);GO:0005635(nuclear envelope);GO:0031224(intrinsic component of membrane);GO:0071456(cellular response to hypoxia);GO:0005521(lamin binding);GO:0010917(negative regulation of mitochondrial membrane potential);GO:0016239(positive regulation of macroautophagy);GO:0035694(mitochondrial protein catabolic process);GO:0035794(positive regulation of mitochondrial membrane permeability);GO:0060548(negative regulation of cell death);GO:0097345(mitochondrial outer membrane permeabilization);GO:1903146(regulation of mitophagy);GO:1903214(regulation of protein targeting to mitochondrion);GO:0005829(cytosol)","04137(Mitophagy - animal)","K15465","NA","BCL2 interacting protein 3 like [Source:HGNC Symbol;Acc:HGNC:1085]",{"v":36.013851,"d":"36.01"},{"v":5.741488,"d":"5.74"},{"v":6.2725640112807,"d":"6.27"},{"v":2.6490552883584,"d":"2.65"},{"v":3.81973087712961E-4,"d":"0.00"},{"v":0.0106307784242814,"d":"0.01"},"up","yes"]
[40592,0,"chr12","-",44508282,44876355,"ENST00000452445",21,3196,"MSTRG.3304","NELL2","GO:0005623(cell);GO:0005509(calcium ion binding);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0070050(neuron cellular homeostasis)","NA","NA","NA","neural EGFL like 2 [Source:HGNC Symbol;Acc:HGNC:7751]",{"v":0.358974,"d":"0.36"},{"v":1.795911,"d":"1.80"},{"v":0.199884069978969,"d":"0.20"},{"v":-2.32276459568184,"d":"-2.32"},{"v":0.000383951311953335,"d":"0.00"},{"v":0.0106356395338075,"d":"0.01"},"down","yes"]
[32210,0,"chr11","-",68154863,68213415,"ENST00000304363",11,5837,"MSTRG.2627","KMT5B","GO:0005634(nucleus);GO:0008168(methyltransferase activity);GO:0016740(transferase activity);GO:0032259(methylation);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0016569(covalent chromatin modification);GO:0005694(chromosome);GO:0018024(histone-lysine N-methyltransferase activity);GO:0042799(histone methyltransferase activity (H4-K20 specific));GO:0034773(histone H4-K20 trimethylation);GO:0005654(nucleoplasm);GO:0007517(muscle organ development);GO:0016571(histone methylation);GO:0000780(condensed nuclear chromosome, centromeric region)","00310(Lysine degradation)","K11429","EC:2.1.1.43","lysine methyltransferase 5B [Source:HGNC Symbol;Acc:HGNC:24283]",{"v":2.755605,"d":"2.76"},{"v":0.430091,"d":"0.43"},{"v":6.40702781504379,"d":"6.41"},{"v":2.67965525373592,"d":"2.68"},{"v":0.000384275538247267,"d":"0.00"},{"v":0.0106356395338075,"d":"0.01"},"up","yes"]
[9401,0,"chr1","-",113761833,113812448,"ENST00000612242",7,6592,"MSTRG.817","RSBN1","GO:0005634(nucleus)","NA","NA","NA","round spermatid basic protein 1 [Source:HGNC Symbol;Acc:HGNC:25642]",{"v":2.132404,"d":"2.13"},{"v":0.331489,"d":"0.33"},{"v":6.43280470845187,"d":"6.43"},{"v":2.68544789101244,"d":"2.69"},{"v":0.000384297668621,"d":"0.00"},{"v":0.0106356395338075,"d":"0.01"},"up","yes"]
[9400,0,"chr1","-",113761832,113812476,"ENST00000261441",7,6621,"MSTRG.817","RSBN1","GO:0005634(nucleus)","NA","NA","NA","round spermatid basic protein 1 [Source:HGNC Symbol;Acc:HGNC:25642]",{"v":2.123065,"d":"2.12"},{"v":0.330037,"d":"0.33"},{"v":6.43280904868242,"d":"6.43"},{"v":2.68544886440232,"d":"2.69"},{"v":0.000384297668621,"d":"0.00"},{"v":0.0106356395338075,"d":"0.01"},"up","yes"]
[119414,0,"chr2","-",219249711,219254032,"ENST00000248437",4,2162,"MSTRG.9451","TUBA4A","GO:0005737(cytoplasm);GO:0005525(GTP binding);GO:0000166(nucleotide binding);GO:0003924(GTPase activity);GO:0015630(microtubule cytoskeleton);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0005200(structural constituent of cytoskeleton);GO:0007010(cytoskeleton organization);GO:0005874(microtubule);GO:0005576(extracellular region);GO:0007017(microtubule-based process);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0000086(G2/M transition of mitotic cell cycle);GO:0010389(regulation of G2/M transition of mitotic cell cycle);GO:0097711(ciliary basal body docking);GO:0002576(platelet degranulation);GO:0019899(enzyme binding)","04145(Phagosome);04210(Apoptosis);04530(Tight junction);04540(Gap junction);05130(Pathogenic Escherichia coli infection)","K07374","NA","tubulin alpha 4a [Source:HGNC Symbol;Acc:HGNC:12407]",{"v":9.568314,"d":"9.57"},{"v":45.435169,"d":"45.44"},{"v":0.21059267986876,"d":"0.21"},{"v":-2.24747280525013,"d":"-2.25"},{"v":0.00038567700819262,"d":"0.00"},{"v":0.0106589059191558,"d":"0.01"},"down","yes"]
[79284,0,"chr17","+",8435908,8467658,"ENST00000402554",10,1858,"MSTRG.6431","NDEL1","GO:0007399(nervous system development);GO:0007100(mitotic centrosome separation);GO:0060052(neurofilament cytoskeleton organization);GO:2000574(regulation of microtubule motor activity);GO:0006810(transport);GO:0005737(cytoplasm);GO:0005694(chromosome);GO:1904115(axon cytoplasm);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0006508(proteolysis);GO:0007275(multicellular organism development);GO:0030154(cell differentiation);GO:0005874(microtubule);GO:0005815(microtubule organizing center);GO:0005819(spindle);GO:0042802(identical protein binding);GO:0007059(chromosome segregation);GO:0000775(chromosome, centromeric region);GO:0000776(kinetochore);GO:0000777(condensed chromosome kinetochore);GO:0005813(centrosome);GO:0005829(cytosol);GO:0008017(microtubule binding);GO:0007062(sister chromatid cohesion);GO:0005871(kinesin complex);GO:0016477(cell migration);GO:0033157(regulation of intracellular protein transport);GO:0047496(vesicle transport along microtubule);GO:0032403(protein complex binding);GO:0043014(alpha-tubulin binding);GO:0048487(beta-tubulin binding);GO:0070012(oligopeptidase activity);GO:0000132(establishment of mitotic spindle orientation);GO:0000226(microtubule cytoskeleton organization);GO:0001764(neuron migration);GO:0001833(inner cell mass cell proliferation);GO:0007020(microtubule nucleation);GO:0008090(retrograde axonal transport);GO:0008286(insulin receptor signaling pathway);GO:0010975(regulation of neuron projection development);GO:0021799(cerebral cortex radially oriented cell migration);GO:0021955(central nervous system neuron axonogenesis);GO:0031175(neuron projection development);GO:0043547(positive regulation of GTPase activity);GO:0045773(positive regulation of axon extension);GO:0048680(positive regulation of axon regeneration);GO:0051081(nuclear envelope disassembly);GO:0051303(establishment of chromosome localization);GO:0051642(centrosome localization);GO:0090630(activation of GTPase activity);GO:1990138(neuron projection extension);GO:0005635(nuclear envelope);GO:0005875(microtubule associated complex);GO:0008021(synaptic vesicle);GO:0030424(axon);GO:0031252(cell leading edge);GO:0043203(axon hillock);GO:0044297(cell body);GO:0060053(neurofilament cytoskeleton);GO:0090724(central region of growth cone)","NA","NA","NA","nudE neurodevelopment protein 1 like 1 [Source:HGNC Symbol;Acc:HGNC:17620]",{"v":0.969394,"d":"0.97"},{"v":4.741834,"d":"4.74"},{"v":0.204434402385237,"d":"0.20"},{"v":-2.29029010030325,"d":"-2.29"},{"v":0.000387647706376795,"d":"0.00"},{"v":0.0106904311674995,"d":"0.01"},"down","yes"]
[132582,0,"chr22","-",50527792,50530012,"ENST00000487162",2,2049,"MSTRG.10610","TYMP","GO:0016740(transferase activity);GO:0016757(transferase activity, transferring glycosyl groups);GO:0008083(growth factor activity);GO:0008152(metabolic process);GO:0007275(multicellular organism development);GO:0030154(cell differentiation);GO:0006935(chemotaxis);GO:0016763(transferase activity, transferring pentosyl groups);GO:0004645(phosphorylase activity);GO:0006206(pyrimidine nucleobase metabolic process);GO:0006213(pyrimidine nucleoside metabolic process);GO:0005829(cytosol);GO:0009032(thymidine phosphorylase activity);GO:0016154(pyrimidine-nucleoside phosphorylase activity);GO:0043097(pyrimidine nucleoside salvage);GO:0001525(angiogenesis);GO:0042803(protein homodimerization activity);GO:0046135(pyrimidine nucleoside catabolic process);GO:0000002(mitochondrial genome maintenance);GO:0031641(regulation of myelination);GO:0051969(regulation of transmission of nerve impulse);GO:1905333(regulation of gastric motility)","00240(Pyrimidine metabolism);00983(Drug metabolism - other enzymes);05219(Bladder cancer)","NA","NA","thymidine phosphorylase [Source:HGNC Symbol;Acc:HGNC:3148]",{"v":1.032332,"d":"1.03"},{"v":5.038923,"d":"5.04"},{"v":0.204871556878325,"d":"0.20"},{"v":-2.28720839164588,"d":"-2.29"},{"v":3.87898199831444E-4,"d":"0.00"},{"v":0.0106904311674995,"d":"0.01"},"down","yes"]
[173547,0,"chr7","+",44039523,44042306,"ENST00000441052",2,2590,"MSTRG.13624","LINC00957","NA","NA","NA","NA","long intergenic non-protein coding RNA 957 [Source:HGNC Symbol;Acc:HGNC:22332]",{"v":0.370484,"d":"0.37"},{"v":1.858765,"d":"1.86"},{"v":0.199317288629816,"d":"0.20"},{"v":-2.32686124101379,"d":"-2.33"},{"v":0.000388945252312801,"d":"0.00"},{"v":0.0107043792110789,"d":"0.01"},"down","yes"]
[88542,0,"chr17","+",76736311,76778572,"ENST00000588460",13,3612,"MSTRG.7259","MFSD11","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0003674(molecular_function);GO:0008150(biological_process);GO:0005575(cellular_component)","NA","NA","NA","major facilitator superfamily domain containing 11 [Source:HGNC Symbol;Acc:HGNC:25458]",{"v":0.414304,"d":"0.41"},{"v":2.053523,"d":"2.05"},{"v":0.201752792639771,"d":"0.20"},{"v":-2.30933945162141,"d":"-2.31"},{"v":0.000395778559442252,"d":"0.00"},{"v":0.0108627849955972,"d":"0.01"},"down","yes"]
[188005,0,"chr8","-",143580620,143587564,"ENST00000530445",5,1217,"MSTRG.14619","EEF1D","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0006412(translation);GO:0005829(cytosol);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0001650(fibrillar center);GO:0005783(endoplasmic reticulum);GO:0005515(protein binding);GO:0004871(signal transducer activity);GO:0003746(translation elongation factor activity);GO:0006414(translational elongation);GO:0005853(eukaryotic translation elongation factor 1 complex);GO:0007165(signal transduction);GO:0045296(cadherin binding);GO:0043123(positive regulation of I-kappaB kinase/NF-kappaB signaling);GO:0008135(translation factor activity, RNA binding);GO:0071479(cellular response to ionizing radiation)","05168(Herpes simplex infection)","NA","NA","eukaryotic translation elongation factor 1 delta [Source:HGNC Symbol;Acc:HGNC:3211]",{"v":1.083822,"d":"1.08"},{"v":5.346181,"d":"5.35"},{"v":0.202728265279458,"d":"0.20"},{"v":-2.30238084507794,"d":"-2.30"},{"v":0.000396144327447101,"d":"0.00"},{"v":0.0108627849955972,"d":"0.01"},"down","yes"]
[9955,0,"chr1","-",144425517,144461674,"ENST00000584793",21,3084,"ENSG00000266338","NBPF15","GO:0005737(cytoplasm)","NA","NA","NA","NBPF member 15 [Source:HGNC Symbol;Acc:HGNC:28791]",{"v":2.25196,"d":"2.25"},{"v":0.341273,"d":"0.34"},{"v":6.59870543523806,"d":"6.60"},{"v":2.72218301759935,"d":"2.72"},{"v":3.96347825289122E-4,"d":"0.00"},{"v":0.0108627849955972,"d":"0.01"},"up","yes"]
[101381,"j","chr19","-",39834453,39846384,"MSTRG.8137.1",9,1024,"MSTRG.8137","FBL","NA","NA","NA","NA","NA",{"v":15.41102,"d":"15.41"},{"v":2.410973,"d":"2.41"},{"v":6.39203342385004,"d":"6.39"},{"v":2.67627495211705,"d":"2.68"},{"v":0.000398197794190861,"d":"0.00"},{"v":0.010898392740593,"d":"0.01"},"up","yes"]
[54926,0,"chr14","-",50905218,50944483,"ENST00000544180",19,2696,"MSTRG.4385","PYGL","GO:0016740(transferase activity);GO:0016757(transferase activity, transferring glycosyl groups);GO:0005975(carbohydrate metabolic process);GO:0030170(pyridoxal phosphate binding);GO:0004645(phosphorylase activity);GO:0008184(glycogen phosphorylase activity);GO:0102499(-);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0042803(protein homodimerization activity);GO:0005515(protein binding);GO:0003824(catalytic activity);GO:0008152(metabolic process);GO:0005576(extracellular region);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0043312(neutrophil degranulation);GO:0034774(secretory granule lumen);GO:1904813(ficolin-1-rich granule lumen);GO:0008144(drug binding);GO:0005980(glycogen catabolic process);GO:0042593(glucose homeostasis);GO:0005977(glycogen metabolic process);GO:0002060(purine nucleobase binding);GO:0005536(glucose binding);GO:0016208(AMP binding);GO:0019842(vitamin binding);GO:0032052(bile acid binding);GO:0030246(carbohydrate binding);GO:0006015(5-phosphoribose 1-diphosphate biosynthetic process);GO:0070266(necroptotic process)","00500(Starch and sucrose metabolism);04217(Necroptosis);04910(Insulin signaling pathway);04922(Glucagon signaling pathway);04931(Insulin resistance)","K00688","EC:2.4.1.1","glycogen phosphorylase L [Source:HGNC Symbol;Acc:HGNC:9725]",{"v":1.146803,"d":"1.15"},{"v":5.524572,"d":"5.52"},{"v":0.207582234424676,"d":"0.21"},{"v":-2.26824511652948,"d":"-2.27"},{"v":4.01699833416642E-4,"d":"0.00"},{"v":0.0109790556680228,"d":"0.01"},"down","yes"]
[80227,0,"chr17","+",18184239,18209954,"ENST00000399138",4,2748,"MSTRG.6495","ALKBH5","GO:0003723(RNA binding);GO:0006397(mRNA processing);GO:0005634(nucleus);GO:0016607(nuclear speck);GO:0005794(Golgi apparatus);GO:0046872(metal ion binding);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0030154(cell differentiation);GO:0051213(dioxygenase activity);GO:0006406(mRNA export from nucleus);GO:0007283(spermatogenesis);GO:0035515(oxidative RNA demethylase activity);GO:0035553(oxidative single-stranded RNA demethylation);GO:0016706(oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors);GO:0001666(response to hypoxia);GO:0006307(DNA dealkylation involved in DNA repair)","NA","NA","NA","alkB homolog 5, RNA demethylase [Source:HGNC Symbol;Acc:HGNC:25996]",{"v":2.18653,"d":"2.19"},{"v":10.389368,"d":"10.39"},{"v":0.210458422494997,"d":"0.21"},{"v":-2.24839284774763,"d":"-2.25"},{"v":0.00040558373104742,"d":"0.00"},{"v":0.0110669496364535,"d":"0.01"},"down","yes"]
[177772,0,"chr7","-",108470422,108526071,"ENST00000426128",10,4268,"MSTRG.13912","PNPLA8","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005524(ATP binding);GO:0016787(hydrolase activity);GO:0005794(Golgi apparatus);GO:0006629(lipid metabolic process);GO:0008152(metabolic process);GO:0016042(lipid catabolic process);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0006631(fatty acid metabolic process);GO:0000139(Golgi membrane);GO:0048471(perinuclear region of cytoplasm);GO:0005777(peroxisome);GO:0005778(peroxisomal membrane);GO:0005622(intracellular);GO:0008219(cell death);GO:0001516(prostaglandin biosynthetic process);GO:0019369(arachidonic acid metabolic process);GO:0004623(phospholipase A2 activity);GO:0036151(phosphatidylcholine acyl-chain remodeling);GO:0036152(phosphatidylethanolamine acyl-chain remodeling);GO:0043651(linoleic acid metabolic process);GO:0004622(lysophospholipase activity);GO:0034638(phosphatidylcholine catabolic process);GO:0047499(calcium-independent phospholipase A2 activity);GO:0046338(phosphatidylethanolamine catabolic process);GO:0050482(arachidonic acid secretion)","NA","NA","NA","patatin like phospholipase domain containing 8 [Source:HGNC Symbol;Acc:HGNC:28900]",{"v":0.228576,"d":"0.23"},{"v":1.134452,"d":"1.13"},{"v":0.201485827518485,"d":"0.20"},{"v":-2.31124973150825,"d":"-2.31"},{"v":0.000406034234690985,"d":"0.00"},{"v":0.0110669496364535,"d":"0.01"},"down","yes"]
[2840,0,"chr1","-",24899518,24929877,"ENST00000308873",5,3861,"MSTRG.249","RUNX3","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0043231(intracellular membrane-bounded organelle);GO:0005524(ATP binding);GO:0005730(nucleolus);GO:0005829(cytosol);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0005515(protein binding);GO:0045893(positive regulation of transcription, DNA-templated);GO:0005654(nucleoplasm);GO:0000981(RNA polymerase II transcription factor activity, sequence-specific DNA binding);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0045786(negative regulation of cell cycle);GO:0000790(nuclear chromatin);GO:0006366(transcription from RNA polymerase II promoter);GO:0006468(protein phosphorylation);GO:0000977(RNA polymerase II regulatory region sequence-specific DNA binding);GO:0050680(negative regulation of epithelial cell proliferation);GO:0030097(hemopoiesis);GO:0048935(peripheral nervous system neuron development);GO:0001503(ossification);GO:0002062(chondrocyte differentiation);GO:0071559(response to transforming growth factor beta);GO:0045595(regulation of cell differentiation)","04658(Th1 and Th2 cell differentiation)","K09279","NA","runt related transcription factor 3 [Source:HGNC Symbol;Acc:HGNC:10473]",{"v":26.692463,"d":"26.69"},{"v":4.291963,"d":"4.29"},{"v":6.21917360424589,"d":"6.22"},{"v":2.63672288963816,"d":"2.64"},{"v":4.09579742259363E-4,"d":"0.00"},{"v":0.0111482310038903,"d":"0.01"},"up","yes"]
[40834,0,"chr12","-",47841539,47905031,"ENST00000229022",11,4773,"ENSG00000111424","VDR","GO:0008285(negative regulation of cell proliferation);GO:0005634(nucleus);GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0005654(nucleoplasm);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0043565(sequence-specific DNA binding);GO:0005515(protein binding);GO:0003707(steroid hormone receptor activity);GO:0043401(steroid hormone mediated signaling pathway);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0010628(positive regulation of gene expression);GO:0008434(calcitriol receptor activity);GO:0070561(vitamin D receptor signaling pathway);GO:0007165(signal transduction);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0006367(transcription initiation from RNA polymerase II promoter);GO:0090575(RNA polymerase II transcription factor complex);GO:0043235(receptor complex);GO:0010980(positive regulation of vitamin D 24-hydroxylase activity);GO:0046697(decidualization);GO:0045618(positive regulation of keratinocyte differentiation);GO:0045892(negative regulation of transcription, DNA-templated);GO:0070644(vitamin D response element binding);GO:0038186(lithocholic acid receptor activity);GO:0046965(retinoid X receptor binding);GO:1902098(calcitriol binding);GO:1902121(lithocholic acid binding);GO:0000902(cell morphogenesis);GO:0010839(negative regulation of keratinocyte proliferation);GO:0038183(bile acid signaling pathway);GO:0060558(regulation of calcidiol 1-monooxygenase activity);GO:0004879(RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding);GO:0001501(skeletal system development);GO:0006816(calcium ion transport);GO:0006874(cellular calcium ion homeostasis);GO:0007275(multicellular organism development);GO:0007595(lactation);GO:0009887(animal organ morphogenesis);GO:0050892(intestinal absorption);GO:0060058(positive regulation of apoptotic process involved in mammary gland involution);GO:0060745(mammary gland branching involved in pregnancy)","04978(Mineral absorption);04961(Endocrine and other factor-regulated calcium reabsorption);05152(Tuberculosis)","K08539","NA","vitamin D receptor [Source:HGNC Symbol;Acc:HGNC:12679]",{"v":2.589664,"d":"2.59"},{"v":0.402791,"d":"0.40"},{"v":6.42929956230402,"d":"6.43"},{"v":2.68466157222916,"d":"2.68"},{"v":0.000411860479072742,"d":"0.00"},{"v":0.0111890029684338,"d":"0.01"},"up","yes"]
[146256,0,"chr4","+",17577304,17607967,"ENST00000618908",13,2100,"MSTRG.11541","LAP3","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0016787(hydrolase activity);GO:0005622(intracellular);GO:0008233(peptidase activity);GO:0006508(proteolysis);GO:0030145(manganese ion binding);GO:0030496(midbody);GO:0008235(metalloexopeptidase activity);GO:0005925(focal adhesion);GO:0004177(aminopeptidase activity);GO:0070062(extracellular exosome);GO:0019538(protein metabolic process);GO:0005739(mitochondrion);GO:0005802(trans-Golgi network)","00330(Arginine and proline metabolism);00480(Glutathione metabolism)","K11142","EC:3.4.11.1;EC:3.4.11.5","leucine aminopeptidase 3 [Source:HGNC Symbol;Acc:HGNC:18449]",{"v":0.807315,"d":"0.81"},{"v":3.943318,"d":"3.94"},{"v":0.204729874689284,"d":"0.20"},{"v":-2.28820645553878,"d":"-2.29"},{"v":0.000412208569031141,"d":"0.00"},{"v":0.0111890029684338,"d":"0.01"},"down","yes"]
[2433,0,"chr1","-",21218584,21279549,"ENST00000357071",17,3763,"MSTRG.217","ECE1","GO:0048471(perinuclear region of cytoplasm);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0046872(metal ion binding);GO:0016787(hydrolase activity);GO:0005765(lysosomal membrane);GO:0008270(zinc ion binding);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0008233(peptidase activity);GO:0006508(proteolysis);GO:0004222(metalloendopeptidase activity);GO:0008237(metallopeptidase activity);GO:0016485(protein processing);GO:0070062(extracellular exosome);GO:0042803(protein homodimerization activity);GO:0009897(external side of plasma membrane);GO:0042733(embryonic digit morphogenesis);GO:0007507(heart development);GO:0004175(endopeptidase activity);GO:0031982(vesicle);GO:0019229(regulation of vasoconstriction);GO:0003100(regulation of systemic arterial blood pressure by endothelin);GO:0001921(positive regulation of receptor recycling);GO:0016486(peptide hormone processing);GO:0017046(peptide hormone binding);GO:0042447(hormone catabolic process);GO:0005768(endosome);GO:0010814(substance P catabolic process);GO:0010815(bradykinin catabolic process);GO:0010816(calcitonin catabolic process);GO:0034959(endothelin maturation);GO:0043583(ear development);GO:0031302(intrinsic component of endosome membrane);GO:0033093(Weibel-Palade body);GO:0060037(pharyngeal system development)","NA","NA","NA","endothelin converting enzyme 1 [Source:HGNC Symbol;Acc:HGNC:3146]",{"v":2.189311,"d":"2.19"},{"v":0.336994,"d":"0.34"},{"v":6.49658747633489,"d":"6.50"},{"v":2.6996820990983,"d":"2.70"},{"v":0.000413821744918737,"d":"0.00"},{"v":0.011201574142696,"d":"0.01"},"up","yes"]
[142431,0,"chr3","-",167684339,167734510,"ENST00000475915",9,849,"MSTRG.11320","PDCD10","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005794(Golgi apparatus);GO:0005829(cytosol);GO:0042803(protein homodimerization activity);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0006915(apoptotic process);GO:0000139(Golgi membrane);GO:0070062(extracellular exosome);GO:0019901(protein kinase binding);GO:0033138(positive regulation of peptidyl-serine phosphorylation);GO:0050821(protein stabilization);GO:0071902(positive regulation of protein serine/threonine kinase activity);GO:0010628(positive regulation of gene expression);GO:0030335(positive regulation of cell migration);GO:0008284(positive regulation of cell proliferation);GO:0047485(protein N-terminus binding);GO:0043066(negative regulation of apoptotic process);GO:0010629(negative regulation of gene expression);GO:0032874(positive regulation of stress-activated MAPK cascade);GO:0036481(intrinsic apoptotic signaling pathway in response to hydrogen peroxide);GO:0042542(response to hydrogen peroxide);GO:0051683(establishment of Golgi localization);GO:0090168(Golgi reassembly);GO:0001525(angiogenesis);GO:0045747(positive regulation of Notch signaling pathway);GO:0044319(wound healing, spreading of cells);GO:0090051(negative regulation of cell migration involved in sprouting angiogenesis);GO:0090316(positive regulation of intracellular protein transport);GO:0043406(positive regulation of MAP kinase activity);GO:1903588(negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis);GO:1990830(cellular response to leukemia inhibitory factor)","NA","NA","NA","programmed cell death 10 [Source:HGNC Symbol;Acc:HGNC:8761]",{"v":8.82325,"d":"8.82"},{"v":1.350065,"d":"1.35"},{"v":6.53542607207801,"d":"6.54"},{"v":2.70828129448075,"d":"2.71"},{"v":0.000414358671474246,"d":"0.00"},{"v":0.011201574142696,"d":"0.01"},"up","yes"]
[198202,0,"chrX","+",71910818,72153286,"ENST00000633930",8,13660,"ENSG00000204131","NHSL2","GO:0030154(cell differentiation)","NA","NA","NA","NHS like 2 [Source:HGNC Symbol;Acc:HGNC:33737]",{"v":8.361188,"d":"8.36"},{"v":1.347606,"d":"1.35"},{"v":6.20447519527221,"d":"6.20"},{"v":2.63330918534382,"d":"2.63"},{"v":4.15121298602249E-4,"d":"0.00"},{"v":0.011201574142696,"d":"0.01"},"up","yes"]
[188404,0,"chr8","-",144451120,144457928,"ENST00000533173",2,6158,"MSTRG.14638","CYHR1","GO:0005737(cytoplasm);GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0005654(nucleoplasm);GO:0005515(protein binding);GO:0048471(perinuclear region of cytoplasm);GO:0016020(membrane);GO:0016021(integral component of membrane)","NA","NA","NA","cysteine and histidine rich 1 [Source:HGNC Symbol;Acc:HGNC:17806]",{"v":0.817403,"d":"0.82"},{"v":0.122133,"d":"0.12"},{"v":6.69272841901861,"d":"6.69"},{"v":2.74259447306842,"d":"2.74"},{"v":0.000415235473098893,"d":"0.00"},{"v":0.011201574142696,"d":"0.01"},"up","yes"]
[133860,"j","chr3","-",17158522,17742623,"MSTRG.10755.2",22,5072,"MSTRG.10755","TBC1D5","NA","NA","NA","NA","NA",{"v":2.739078,"d":"2.74"},{"v":0.428801,"d":"0.43"},{"v":6.38776028973813,"d":"6.39"},{"v":2.67531017447506,"d":"2.68"},{"v":0.00041550209322513,"d":"0.00"},{"v":0.011201574142696,"d":"0.01"},"up","yes"]
[106659,0,"chr19","-",58551566,58554973,"ENST00000601220",6,885,"MSTRG.8479","CHMP2A","GO:0005622(intracellular);GO:0007034(vacuolar transport);GO:0006810(transport);GO:0016020(membrane);GO:0015031(protein transport);GO:0005515(protein binding);GO:0005829(cytosol);GO:0005768(endosome);GO:0031902(late endosome membrane);GO:0031210(phosphatidylcholine binding);GO:0070062(extracellular exosome);GO:0051291(protein heterooligomerization);GO:0016197(endosomal transport);GO:0016236(macroautophagy);GO:0019058(viral life cycle);GO:0036258(multivesicular body assembly);GO:0039702(viral budding via host ESCRT complex);GO:0019904(protein domain specific binding);GO:1903543(positive regulation of exosomal secretion);GO:0010458(exit from mitosis);GO:0005635(nuclear envelope);GO:0051258(protein polymerization);GO:0010324(membrane invagination);GO:0051260(protein homooligomerization);GO:0007080(mitotic metaphase plate congression);GO:0010824(regulation of centrosome duplication);GO:0000785(chromatin);GO:0000920(cell separation after cytokinesis);GO:0006997(nucleus organization);GO:0031468(nuclear envelope reassembly);GO:0045184(establishment of protein localization);GO:0050792(regulation of viral process);GO:0060548(negative regulation of cell death);GO:1901673(regulation of mitotic spindle assembly);GO:1902188(positive regulation of viral release from host cell);GO:1903723(negative regulation of centriole elongation);GO:1904903(ESCRT III complex disassembly);GO:0000815(ESCRT III complex);GO:0030117(membrane coat)","04144(Endocytosis);04217(Necroptosis)","K12191","NA","charged multivesicular body protein 2A [Source:HGNC Symbol;Acc:HGNC:30216]",{"v":10.145734,"d":"10.15"},{"v":1.559669,"d":"1.56"},{"v":6.50505588044643,"d":"6.51"},{"v":2.7015614501939,"d":"2.70"},{"v":0.000417926262009833,"d":"0.00"},{"v":0.0112515984661913,"d":"0.01"},"up","yes"]
[36420,0,"chr11","+",124115404,124124841,"ENST00000361352",10,1863,"ENSG00000110002","VWA5A","NA","NA","NA","NA","von Willebrand factor A domain containing 5A [Source:HGNC Symbol;Acc:HGNC:6658]",{"v":0.519282,"d":"0.52"},{"v":2.58926,"d":"2.59"},{"v":0.200552281346794,"d":"0.20"},{"v":-2.31794971752085,"d":"-2.32"},{"v":0.000420660056193584,"d":"0.00"},{"v":0.0113098114021177,"d":"0.01"},"down","yes"]
[33068,0,"chr11","-",74454841,74467628,"ENST00000310128",3,3143,"MSTRG.2704","KCNE3","GO:1903817(negative regulation of voltage-gated potassium channel activity);GO:0006810(transport);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0006811(ion transport);GO:0005244(voltage-gated ion channel activity);GO:0005249(voltage-gated potassium channel activity);GO:0005267(potassium channel activity);GO:0006813(potassium ion transport);GO:0034765(regulation of ion transmembrane transport);GO:0071805(potassium ion transmembrane transport);GO:0005886(plasma membrane);GO:0042995(cell projection);GO:0045121(membrane raft);GO:0030425(dendrite);GO:0005515(protein binding);GO:0043204(perikaryon);GO:0015459(potassium channel regulator activity);GO:0031982(vesicle);GO:0086091(regulation of heart rate by cardiac conduction);GO:0008076(voltage-gated potassium channel complex);GO:0032809(neuronal cell body membrane);GO:1902260(negative regulation of delayed rectifier potassium channel activity);GO:0044325(ion channel binding);GO:0043266(regulation of potassium ion transport);GO:1901387(positive regulation of voltage-gated calcium channel activity);GO:1903765(negative regulation of potassium ion export across plasma membrane);GO:1905025(negative regulation of membrane repolarization during ventricular cardiac muscle cell action potential)","04974(Protein digestion and absorption)","K04897","NA","potassium voltage-gated channel subfamily E regulatory subunit 3 [Source:HGNC Symbol;Acc:HGNC:6243]",{"v":3.845832,"d":"3.85"},{"v":0.601325,"d":"0.60"},{"v":6.39559639130254,"d":"6.40"},{"v":2.67707889712983,"d":"2.68"},{"v":0.000421471811209684,"d":"0.00"},{"v":0.011316260787269,"d":"0.01"},"up","yes"]
[116488,0,"chr2","-",173909941,173963835,"ENST00000640958",5,2142,"MSTRG.9242","SP3","GO:0005634(nucleus);GO:0003676(nucleic acid binding);GO:0046872(metal ion binding);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0005515(protein binding);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0045893(positive regulation of transcription, DNA-templated);GO:0000987(core promoter proximal region sequence-specific DNA binding);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0005654(nucleoplasm);GO:0000981(RNA polymerase II transcription factor activity, sequence-specific DNA binding);GO:0045892(negative regulation of transcription, DNA-templated);GO:0016605(PML body);GO:0000977(RNA polymerase II regulatory region sequence-specific DNA binding);GO:0016925(protein sumoylation);GO:0000979(RNA polymerase II core promoter sequence-specific DNA binding);GO:0001078(transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0003682(chromatin binding);GO:0003690(double-stranded DNA binding);GO:0001503(ossification);GO:0001701(in utero embryonic development);GO:0001779(natural killer cell differentiation);GO:0001829(trophectodermal cell differentiation);GO:0001889(liver development);GO:0001892(embryonic placenta development);GO:0030183(B cell differentiation);GO:0030217(T cell differentiation);GO:0030218(erythrocyte differentiation);GO:0030219(megakaryocyte differentiation);GO:0030224(monocyte differentiation);GO:0030324(lung development);GO:0030851(granulocyte differentiation);GO:0043353(enucleate erythrocyte differentiation);GO:0048596(embryonic camera-type eye morphogenesis);GO:0048706(embryonic skeletal system development);GO:0060136(embryonic process involved in female pregnancy);GO:0060216(definitive hemopoiesis);GO:0017053(transcriptional repressor complex)","NA","NA","NA","Sp3 transcription factor [Source:HGNC Symbol;Acc:HGNC:11208]",{"v":12.964857,"d":"12.96"},{"v":2.07243,"d":"2.07"},{"v":6.25587209218164,"d":"6.26"},{"v":2.64521101554461,"d":"2.65"},{"v":0.000423014250886603,"d":"0.00"},{"v":0.0113422845481627,"d":"0.01"},"up","yes"]
[182686,0,"chr8","-",30063012,30083207,"ENST00000256255",6,2154,"MSTRG.14272","SARAF","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0006811(ion transport);GO:0006816(calcium ion transport);GO:0030176(integral component of endoplasmic reticulum membrane);GO:0005515(protein binding);GO:2001256(regulation of store-operated calcium entry)","NA","NA","NA","store-operated calcium entry associated regulatory factor [Source:HGNC Symbol;Acc:HGNC:28789]",{"v":116.318939,"d":"116.32"},{"v":18.832628,"d":"18.83"},{"v":6.17645816611468,"d":"6.18"},{"v":2.62677977486391,"d":"2.63"},{"v":0.000424157878507087,"d":"0.00"},{"v":0.0113575589985091,"d":"0.01"},"up","yes"]
[11834,0,"chr1","+",155689091,155738526,"ENST00000421487",12,1470,"MSTRG.1064","DAP3","GO:0003723(RNA binding);GO:0000166(nucleotide binding);GO:0005654(nucleoplasm);GO:0005739(mitochondrion);GO:0030529(intracellular ribonucleoprotein complex);GO:0005840(ribosome);GO:0005525(GTP binding);GO:0015935(small ribosomal subunit);GO:0006915(apoptotic process);GO:0005515(protein binding);GO:0005761(mitochondrial ribosome);GO:0003735(structural constituent of ribosome);GO:0005763(mitochondrial small ribosomal subunit);GO:0005743(mitochondrial inner membrane);GO:0070125(mitochondrial translational elongation);GO:0070126(mitochondrial translational termination);GO:0097190(apoptotic signaling pathway)","NA","NA","NA","death associated protein 3 [Source:HGNC Symbol;Acc:HGNC:2673]",{"v":0.713648,"d":"0.71"},{"v":3.534567,"d":"3.53"},{"v":0.201905353611913,"d":"0.20"},{"v":-2.30824892999826,"d":"-2.31"},{"v":4.29595608232745E-4,"d":"0.00"},{"v":0.0114876187779859,"d":"0.01"},"down","yes"]
[56573,0,"chr14","-",73275210,73355769,"ENST00000359560",9,3309,"MSTRG.4515","NUMB","GO:0016020(membrane);GO:0005515(protein binding);GO:0007275(multicellular organism development);GO:0007399(nervous system development);GO:0005925(focal adhesion);GO:0005886(plasma membrane);GO:0045296(cadherin binding);GO:0030335(positive regulation of cell migration);GO:0030136(clathrin-coated vesicle);GO:0050769(positive regulation of neurogenesis);GO:1903077(negative regulation of protein localization to plasma membrane);GO:0021670(lateral ventricle development);GO:0021849(neuroblast division in subventricular zone);GO:0008013(beta-catenin binding);GO:0045294(alpha-catenin binding);GO:0007405(neuroblast proliferation);GO:0007409(axonogenesis);GO:0030862(positive regulation of polarized epithelial cell differentiation);GO:0030900(forebrain development);GO:0034332(adherens junction organization);GO:0045746(negative regulation of Notch signaling pathway);GO:0060487(lung epithelial cell differentiation);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005769(early endosome);GO:0016323(basolateral plasma membrane);GO:0019897(extrinsic component of plasma membrane);GO:0031410(cytoplasmic vesicle);GO:0045177(apical part of cell)","04330(Notch signaling pathway)","NA","NA","NUMB, endocytic adaptor protein [Source:HGNC Symbol;Acc:HGNC:8060]",{"v":2.882009,"d":"2.88"},{"v":0.448509,"d":"0.45"},{"v":6.42575511305236,"d":"6.43"},{"v":2.68386600043009,"d":"2.68"},{"v":0.00043134165114181,"d":"0.00"},{"v":0.011518743040208,"d":"0.01"},"up","yes"]
[74192,0,"chr16","+",66880361,66891096,"ENST00000311765",2,7146,"ENSG00000172840","PDP2","GO:0003824(catalytic activity);GO:0006470(protein dephosphorylation);GO:0004722(protein serine/threonine phosphatase activity);GO:0043169(cation binding);GO:0046872(metal ion binding);GO:0016787(hydrolase activity);GO:0005739(mitochondrion);GO:0004721(phosphoprotein phosphatase activity);GO:0005759(mitochondrial matrix);GO:0010510(regulation of acetyl-CoA biosynthetic process from pyruvate);GO:0004741([pyruvate dehydrogenase (lipoamide)] phosphatase activity)","NA","NA","NA","pyruvate dehyrogenase phosphatase catalytic subunit 2 [Source:HGNC Symbol;Acc:HGNC:30263]",{"v":0.782552,"d":"0.78"},{"v":0.119734,"d":"0.12"},{"v":6.53575425526584,"d":"6.54"},{"v":2.70835373908726,"d":"2.71"},{"v":0.000438578224903581,"d":"0.00"},{"v":0.0116962074317952,"d":"0.01"},"up","yes"]
[68709,0,"chr16","+",3065663,3069440,"ENST00000552664",7,731,"MSTRG.5581","IL32","GO:0016020(membrane);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0006955(immune response);GO:0005125(cytokine activity);GO:0005615(extracellular space);GO:0005829(cytosol);GO:0007155(cell adhesion);GO:0006952(defense response)","NA","NA","NA","interleukin 32 [Source:HGNC Symbol;Acc:HGNC:16830]",{"v":1.144324,"d":"1.14"},{"v":5.766849,"d":"5.77"},{"v":0.198431413758189,"d":"0.20"},{"v":-2.33328765744073,"d":"-2.33"},{"v":4.43070066618314E-4,"d":"0.00"},{"v":0.0118000948563165,"d":"0.01"},"down","yes"]
[102067,0,"chr19","+",42268537,42295796,"ENST00000572681",21,8218,"MSTRG.8198","CIC","GO:0005634(nucleus);GO:0003677(DNA binding);GO:0043231(intracellular membrane-bounded organelle);GO:0005654(nucleoplasm);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0005515(protein binding);GO:0000122(negative regulation of transcription from RNA polymerase II promoter)","NA","NA","NA","capicua transcriptional repressor [Source:HGNC Symbol;Acc:HGNC:14214]",{"v":2.843375,"d":"2.84"},{"v":0.456221,"d":"0.46"},{"v":6.23245093934738,"d":"6.23"},{"v":2.63979962114416,"d":"2.64"},{"v":0.000444667746968532,"d":"0.00"},{"v":0.0118209876554744,"d":"0.01"},"up","yes"]
[87624,0,"chr17","+",74203704,74209896,"ENST00000533498",4,532,"MSTRG.7171","RPL38","GO:0006412(translation);GO:0030529(intracellular ribonucleoprotein complex);GO:0005622(intracellular);GO:0003735(structural constituent of ribosome);GO:0005840(ribosome);GO:0005925(focal adhesion);GO:0005829(cytosol);GO:0006413(translational initiation);GO:0003723(RNA binding);GO:0006364(rRNA processing);GO:0000184(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay);GO:0019083(viral transcription);GO:0006614(SRP-dependent cotranslational protein targeting to membrane);GO:0022625(cytosolic large ribosomal subunit);GO:0022618(ribonucleoprotein complex assembly);GO:0001501(skeletal system development);GO:0001503(ossification);GO:0006417(regulation of translation);GO:0007605(sensory perception of sound);GO:0034463(90S preribosome assembly);GO:0042474(middle ear morphogenesis);GO:0048318(axial mesoderm development);GO:0033291(eukaryotic 80S initiation complex)","03010(Ribosome)","NA","NA","ribosomal protein L38 [Source:HGNC Symbol;Acc:HGNC:10349]",{"v":45.110348,"d":"45.11"},{"v":209.901001,"d":"209.90"},{"v":0.214912495819875,"d":"0.21"},{"v":-2.21817872597342,"d":"-2.22"},{"v":0.000445049312882979,"d":"0.00"},{"v":0.0118209876554744,"d":"0.01"},"down","yes"]
[163128,0,"chr6","+",18387350,18468874,"ENST00000259939",8,5036,"MSTRG.12697","RNF144B","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0046872(metal ion binding);GO:0016740(transferase activity);GO:0016567(protein ubiquitination);GO:0004842(ubiquitin-protein transferase activity);GO:0005739(mitochondrion);GO:0005515(protein binding);GO:0006915(apoptotic process);GO:0031966(mitochondrial membrane);GO:0000151(ubiquitin ligase complex);GO:0061630(ubiquitin protein ligase activity);GO:0005829(cytosol);GO:0000209(protein polyubiquitination);GO:0042787(protein ubiquitination involved in ubiquitin-dependent protein catabolic process);GO:0043066(negative regulation of apoptotic process);GO:0032436(positive regulation of proteasomal ubiquitin-dependent protein catabolic process);GO:0031624(ubiquitin conjugating enzyme binding)","NA","NA","NA","ring finger protein 144B [Source:HGNC Symbol;Acc:HGNC:21578]",{"v":9.34176,"d":"9.34"},{"v":1.51211,"d":"1.51"},{"v":6.17796324341483,"d":"6.18"},{"v":2.62713128749179,"d":"2.63"},{"v":0.000445880941588004,"d":"0.00"},{"v":0.0118272011690931,"d":"0.01"},"up","yes"]
[57558,0,"chr14","-",89156172,89619130,"ENST00000345097",7,7832,"MSTRG.4593","FOXN3","GO:0005634(nucleus);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0043565(sequence-specific DNA binding);GO:0005515(protein binding);GO:0007049(cell cycle);GO:0097094(craniofacial suture morphogenesis);GO:0030154(cell differentiation);GO:0008022(protein C-terminus binding);GO:0045892(negative regulation of transcription, DNA-templated);GO:0045893(positive regulation of transcription, DNA-templated);GO:0007095(mitotic G2 DNA damage checkpoint)","NA","NA","NA","forkhead box N3 [Source:HGNC Symbol;Acc:HGNC:1928]",{"v":7.24648,"d":"7.25"},{"v":1.175861,"d":"1.18"},{"v":6.16270120362866,"d":"6.16"},{"v":2.62356284424733,"d":"2.62"},{"v":0.000448098978527235,"d":"0.00"},{"v":0.0118701239452436,"d":"0.01"},"up","yes"]
[198813,0,"chrX","-",101009542,101052083,"ENST00000372936",14,3327,"ENSG00000188917","TRMT2B","GO:0006396(RNA processing);GO:0008168(methyltransferase activity);GO:0016740(transferase activity);GO:0008033(tRNA processing);GO:0032259(methylation);GO:0005515(protein binding);GO:0008173(RNA methyltransferase activity);GO:0001510(RNA methylation);GO:0030697(S-adenosylmethionine-dependent tRNA (m5U54) methyltransferase activity);GO:0005739(mitochondrion)","NA","NA","NA","tRNA methyltransferase 2 homolog B [Source:HGNC Symbol;Acc:HGNC:25748]",{"v":3.73124,"d":"3.73"},{"v":0.591243,"d":"0.59"},{"v":6.31084004377219,"d":"6.31"},{"v":2.65783205692258,"d":"2.66"},{"v":0.000449912521925054,"d":"0.00"},{"v":0.0119022312618355,"d":"0.01"},"up","yes"]
[121708,0,"chr20","+",3795739,3805237,"ENST00000467519",16,1960,"MSTRG.9573","CDC25B","GO:0005737(cytoplasm);GO:0016787(hydrolase activity);GO:0005622(intracellular);GO:0051301(cell division);GO:0004725(protein tyrosine phosphatase activity);GO:0006470(protein dephosphorylation);GO:0035335(peptidyl-tyrosine dephosphorylation);GO:0004721(phosphoprotein phosphatase activity);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0007049(cell cycle);GO:1902751(positive regulation of cell cycle G2/M phase transition);GO:0000922(spindle pole);GO:0005813(centrosome);GO:0005815(microtubule organizing center);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0019901(protein kinase binding);GO:0000086(G2/M transition of mitotic cell cycle);GO:0006468(protein phosphorylation);GO:0000278(mitotic cell cycle);GO:0032467(positive regulation of cytokinesis);GO:0008284(positive regulation of cell proliferation);GO:0045931(positive regulation of mitotic cell cycle);GO:0001556(oocyte maturation);GO:0007144(female meiosis I);GO:0045860(positive regulation of protein kinase activity);GO:0005634(nucleus)","04010(MAPK signaling pathway);04110(Cell cycle);04914(Progesterone-mediated oocyte maturation);05206(MicroRNAs in cancer)","NA","NA","cell division cycle 25B [Source:HGNC Symbol;Acc:HGNC:1726]",{"v":5.132195,"d":"5.13"},{"v":0.809982,"d":"0.81"},{"v":6.33618401396574,"d":"6.34"},{"v":2.66361423443596,"d":"2.66"},{"v":0.000452346244686087,"d":"0.00"},{"v":0.0119506375031352,"d":"0.01"},"up","yes"]
[130125,0,"chr22","+",29883213,30026495,"ENST00000351488",19,4464,"MSTRG.10354","MTMR3","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0046872(metal ion binding);GO:0016787(hydrolase activity);GO:0006629(lipid metabolic process);GO:0004725(protein tyrosine phosphatase activity);GO:0016311(dephosphorylation);GO:0035335(peptidyl-tyrosine dephosphorylation);GO:0004721(phosphoprotein phosphatase activity);GO:0005515(protein binding);GO:0005829(cytosol);GO:0019898(extrinsic component of membrane);GO:0006661(phosphatidylinositol biosynthetic process);GO:0004722(protein serine/threonine phosphatase activity);GO:0006470(protein dephosphorylation);GO:0004438(phosphatidylinositol-3-phosphatase activity);GO:0052629(phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity);GO:0016236(macroautophagy);GO:0042149(cellular response to glucose starvation);GO:2000785(regulation of autophagosome assembly);GO:0046856(phosphatidylinositol dephosphorylation);GO:1904562(phosphatidylinositol 5-phosphate metabolic process)","00562(Inositol phosphate metabolism);04070(Phosphatidylinositol signaling system);04140(Autophagy - animal)","K18082","EC:3.1.3.48;EC:3.1.3.64","myotubularin related protein 3 [Source:HGNC Symbol;Acc:HGNC:7451]",{"v":1.10836,"d":"1.11"},{"v":0.168594,"d":"0.17"},{"v":6.57413668339324,"d":"6.57"},{"v":2.71680145191619,"d":"2.72"},{"v":4.57998541505146E-4,"d":"0.00"},{"v":0.0120838335190718,"d":"0.01"},"up","yes"]
[64698,0,"chr15","+",74798652,74802589,"ENST00000568329",10,1552,"MSTRG.5277","CSK","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0004713(protein tyrosine kinase activity);GO:0018108(peptidyl-tyrosine phosphorylation);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0004715(non-membrane spanning protein tyrosine kinase activity);GO:0002376(immune system process);GO:0002250(adaptive immune response);GO:0045087(innate immune response);GO:0042802(identical protein binding);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0050852(T cell receptor signaling pathway);GO:0030154(cell differentiation);GO:0019903(protein phosphatase binding);GO:0070064(proline-rich region binding);GO:0007420(brain development);GO:0008285(negative regulation of cell proliferation);GO:0010989(negative regulation of low-density lipoprotein particle clearance);GO:0032715(negative regulation of interleukin-6 production);GO:0033673(negative regulation of kinase activity);GO:0034332(adherens junction organization);GO:0043406(positive regulation of MAP kinase activity);GO:0045779(negative regulation of bone resorption);GO:0046777(protein autophosphorylation);GO:0048709(oligodendrocyte differentiation);GO:0050765(negative regulation of phagocytosis);GO:0060368(regulation of Fc receptor mediated stimulatory signaling pathway);GO:0070373(negative regulation of ERK1 and ERK2 cascade);GO:0071375(cellular response to peptide hormone stimulus);GO:0005911(cell-cell junction);GO:0045121(membrane raft);GO:0042127(regulation of cell proliferation);GO:0007417(central nervous system development);GO:0005102(receptor binding);GO:0031295(T cell costimulation);GO:0034236(protein kinase A catalytic subunit binding);GO:0038083(peptidyl-tyrosine autophosphorylation);GO:0031234(extrinsic component of cytoplasmic side of plasma membrane);GO:0008022(protein C-terminus binding);GO:0007169(transmembrane receptor protein tyrosine kinase signaling pathway);GO:0007173(epidermal growth factor receptor signaling pathway);GO:0001817(regulation of cytokine production);GO:0042997(negative regulation of Golgi to plasma membrane protein transport)","05120(Epithelial cell signaling in Helicobacter pylori infection)","NA","NA","C-terminal Src kinase [Source:HGNC Symbol;Acc:HGNC:2444]",{"v":4.131354,"d":"4.13"},{"v":0.639432,"d":"0.64"},{"v":6.46097474008182,"d":"6.46"},{"v":2.69175183467139,"d":"2.69"},{"v":0.000467386432212019,"d":"0.00"},{"v":0.0123151034894959,"d":"0.01"},"up","yes"]
[46086,0,"chr12","-",105174208,105236083,"ENST00000551662",21,2190,"MSTRG.3668","APPL2","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005515(protein binding);GO:0007165(signal transduction);GO:0007049(cell cycle);GO:0005768(endosome);GO:0070062(extracellular exosome);GO:0008283(cell proliferation);GO:0010008(endosome membrane);GO:0031901(early endosome membrane);GO:0016581(NuRD complex)","NA","NA","NA","adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2 [Source:HGNC Symbol;Acc:HGNC:18242]",{"v":2.528463,"d":"2.53"},{"v":0.38708,"d":"0.39"},{"v":6.53214580965175,"d":"6.53"},{"v":2.70755699489742,"d":"2.71"},{"v":0.000470601058719469,"d":"0.00"},{"v":0.0123833161568362,"d":"0.01"},"up","yes"]
[98454,0,"chr19","+",17860763,17863304,"ENST00000599870",4,1084,"MSTRG.7977","RPL18A","GO:0003723(RNA binding);GO:0016020(membrane);GO:0006412(translation);GO:0030529(intracellular ribonucleoprotein complex);GO:0003735(structural constituent of ribosome);GO:0005840(ribosome);GO:0005829(cytosol);GO:0005515(protein binding);GO:0006413(translational initiation);GO:0006364(rRNA processing);GO:0000184(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay);GO:0019083(viral transcription);GO:0006614(SRP-dependent cotranslational protein targeting to membrane);GO:0022625(cytosolic large ribosomal subunit);GO:0097327(response to antineoplastic agent)","03010(Ribosome)","NA","NA","ribosomal protein L18a [Source:HGNC Symbol;Acc:HGNC:10311]",{"v":21.024054,"d":"21.02"},{"v":97.039787,"d":"97.04"},{"v":0.216653958648941,"d":"0.22"},{"v":-2.20653549746051,"d":"-2.21"},{"v":0.000471448203249919,"d":"0.00"},{"v":0.0123891328630935,"d":"0.01"},"down","yes"]
[4910,0,"chr1","+",42682987,42702349,"ENST00000436427",7,1524,"MSTRG.472","YBX1","GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0006397(mRNA processing);GO:0008380(RNA splicing);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0043231(intracellular membrane-bounded organelle);GO:0005829(cytosol);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0031965(nuclear membrane);GO:0030529(intracellular ribonucleoprotein complex);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:0005654(nucleoplasm);GO:0070062(extracellular exosome);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0010494(cytoplasmic stress granule);GO:0006366(transcription from RNA polymerase II promoter);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:1903608(protein localization to cytoplasmic stress granule);GO:0001077(transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0051781(positive regulation of cell division);GO:0000398(mRNA splicing, via spliceosome);GO:0070934(CRD-mediated mRNA stabilization);GO:0070937(CRD-mediated mRNA stability complex);GO:0071204(histone pre-mRNA 3'end processing complex);GO:0051020(GTPase binding);GO:0005689(U12-type spliceosomal complex);GO:0003690(double-stranded DNA binding);GO:0003697(single-stranded DNA binding);GO:0003682(chromatin binding);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0001701(in utero embryonic development);GO:0051154(negative regulation of striated muscle cell differentiation)","NA","NA","NA","Y-box binding protein 1 [Source:HGNC Symbol;Acc:HGNC:8014]",{"v":65.082352,"d":"65.08"},{"v":10.699411,"d":"10.70"},{"v":6.0827976418515,"d":"6.08"},{"v":2.60473501046451,"d":"2.60"},{"v":0.000480493669896918,"d":"0.00"},{"v":0.0126100911670029,"d":"0.01"},"up","yes"]
[79856,"j","chr17","+",16381013,16382745,"MSTRG.6460.4",3,560,"MSTRG.6460","UBB","NA","NA","NA","NA","NA",{"v":6.788031,"d":"6.79"},{"v":31.7313,"d":"31.73"},{"v":0.213922247118775,"d":"0.21"},{"v":-2.22484156965906,"d":"-2.22"},{"v":0.000481688463218449,"d":"0.00"},{"v":0.0126247037220751,"d":"0.01"},"down","yes"]
[20666,0,"chr10","-",63167590,63269066,"ENST00000542921",25,8149,"MSTRG.1732","JMJD1C","GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0016569(covalent chromatin modification);GO:0005515(protein binding);GO:0051213(dioxygenase activity);GO:0005654(nucleoplasm);GO:0005622(intracellular);GO:0000976(transcription regulatory region sequence-specific DNA binding);GO:0007596(blood coagulation);GO:0000785(chromatin);GO:0031490(chromatin DNA binding);GO:0032454(histone demethylase activity (H3-K9 specific));GO:0033169(histone H3-K9 demethylation);GO:0046966(thyroid hormone receptor binding)","05202(Transcriptional misregulation in cancers)","K11449","EC:1.14.11.-","jumonji domain containing 1C [Source:HGNC Symbol;Acc:HGNC:12313]",{"v":10.566873,"d":"10.57"},{"v":1.737809,"d":"1.74"},{"v":6.08057214573063,"d":"6.08"},{"v":2.60420707909204,"d":"2.60"},{"v":0.000482375976419353,"d":"0.00"},{"v":0.0126259997637383,"d":"0.01"},"up","yes"]
[87622,0,"chr17","+",74203694,74209461,"ENST00000534490",4,429,"MSTRG.7171","RPL38","GO:0006412(translation);GO:0030529(intracellular ribonucleoprotein complex);GO:0005622(intracellular);GO:0003735(structural constituent of ribosome);GO:0005840(ribosome);GO:0005925(focal adhesion);GO:0005829(cytosol);GO:0006413(translational initiation);GO:0003723(RNA binding);GO:0006364(rRNA processing);GO:0000184(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay);GO:0019083(viral transcription);GO:0006614(SRP-dependent cotranslational protein targeting to membrane);GO:0022625(cytosolic large ribosomal subunit);GO:0022618(ribonucleoprotein complex assembly);GO:0001501(skeletal system development);GO:0001503(ossification);GO:0006417(regulation of translation);GO:0007605(sensory perception of sound);GO:0034463(90S preribosome assembly);GO:0042474(middle ear morphogenesis);GO:0048318(axial mesoderm development);GO:0033291(eukaryotic 80S initiation complex)","03010(Ribosome)","NA","NA","ribosomal protein L38 [Source:HGNC Symbol;Acc:HGNC:10349]",{"v":2.472336,"d":"2.47"},{"v":12.060614,"d":"12.06"},{"v":0.204992548472242,"d":"0.20"},{"v":-2.28635662651044,"d":"-2.29"},{"v":0.000484529709443636,"d":"0.00"},{"v":0.01266561940617,"d":"0.01"},"down","yes"]
[146255,0,"chr4","+",17577192,17607968,"ENST00000226299",13,2213,"MSTRG.11541","LAP3","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0016787(hydrolase activity);GO:0005622(intracellular);GO:0008233(peptidase activity);GO:0006508(proteolysis);GO:0030145(manganese ion binding);GO:0030496(midbody);GO:0008235(metalloexopeptidase activity);GO:0005925(focal adhesion);GO:0004177(aminopeptidase activity);GO:0070062(extracellular exosome);GO:0019538(protein metabolic process);GO:0005739(mitochondrion);GO:0005802(trans-Golgi network)","00330(Arginine and proline metabolism);00480(Glutathione metabolism)","NA","NA","leucine aminopeptidase 3 [Source:HGNC Symbol;Acc:HGNC:18449]",{"v":0.782957,"d":"0.78"},{"v":3.741964,"d":"3.74"},{"v":0.209236914091103,"d":"0.21"},{"v":-2.25679069703989,"d":"-2.26"},{"v":0.000486393199772319,"d":"0.00"},{"v":0.0126975575687265,"d":"0.01"},"down","yes"]
[187358,0,"chr8","+",132775358,132845923,"ENST00000622263",21,3375,"ENSG00000129292","PHF20L1","GO:0005634(nucleus);GO:0006355(regulation of transcription, DNA-templated);GO:0046872(metal ion binding);GO:0005515(protein binding)","NA","NA","NA","PHD finger protein 20 like 1 [Source:HGNC Symbol;Acc:HGNC:24280]",{"v":2.685609,"d":"2.69"},{"v":0.426712,"d":"0.43"},{"v":6.29372738521532,"d":"6.29"},{"v":2.65391468919945,"d":"2.65"},{"v":0.000488418240342584,"d":"0.00"},{"v":0.0127326351509357,"d":"0.01"},"up","yes"]
[101276,0,"chr19","-",39433207,39435936,"ENST00000339471",4,643,"MSTRG.8134","RPS16","GO:0030529(intracellular ribonucleoprotein complex);GO:0003735(structural constituent of ribosome);GO:0006412(translation);GO:0005840(ribosome);GO:0003723(RNA binding);GO:0016020(membrane);GO:0005515(protein binding);GO:0022627(cytosolic small ribosomal subunit);GO:0005925(focal adhesion);GO:0006364(rRNA processing);GO:0042274(ribosomal small subunit biogenesis);GO:0000462(maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA));GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0031012(extracellular matrix);GO:0006413(translational initiation);GO:0000184(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay);GO:0019083(viral transcription);GO:0006614(SRP-dependent cotranslational protein targeting to membrane);GO:0097421(liver regeneration);GO:1990830(cellular response to leukemia inhibitory factor);GO:0015935(small ribosomal subunit)","03010(Ribosome)","K02960","NA","ribosomal protein S16 [Source:HGNC Symbol;Acc:HGNC:10396]",{"v":8.208123,"d":"8.21"},{"v":1.26251,"d":"1.26"},{"v":6.50143206786481,"d":"6.50"},{"v":2.70075753500993,"d":"2.70"},{"v":0.000489263332235954,"d":"0.00"},{"v":0.0127326351509357,"d":"0.01"},"up","yes"]
[178353,0,"chr7","-",124822387,124929983,"ENST00000393329",18,3950,"ENSG00000128513","POT1","GO:0000723(telomere maintenance);GO:0043047(single-stranded telomeric DNA binding);GO:0005634(nucleus);GO:0003677(DNA binding);GO:0005694(chromosome);GO:0005515(protein binding);GO:0000784(nuclear chromosome, telomeric region);GO:0000781(chromosome, telomeric region);GO:0005654(nucleoplasm);GO:0032212(positive regulation of telomere maintenance via telomerase);GO:0051973(positive regulation of telomerase activity);GO:0070200(establishment of protein localization to telomere);GO:0000783(nuclear telomere cap complex);GO:0042162(telomeric DNA binding);GO:0032508(DNA duplex unwinding);GO:0032210(regulation of telomere maintenance via telomerase);GO:0051974(negative regulation of telomerase activity);GO:0032211(negative regulation of telomere maintenance via telomerase);GO:0098505(G-rich strand telomeric DNA binding);GO:0051096(positive regulation of helicase activity);GO:0061821(telomeric D-loop binding);GO:1905773(8-hydroxy-2'-deoxyguanosine DNA binding);GO:0061820(telomeric D-loop disassembly);GO:0007004(telomere maintenance via telomerase);GO:0016233(telomere capping);GO:0070187(shelterin complex);GO:0017151(DEAD/H-box RNA helicase binding);GO:0032202(telomere assembly);GO:0010521(telomerase inhibitor activity);GO:1990955(G-rich single-stranded DNA binding);GO:0060383(positive regulation of DNA strand elongation);GO:1905774(regulation of DNA helicase activity);GO:1905776(positive regulation of DNA helicase activity)","NA","NA","NA","protection of telomeres 1 [Source:HGNC Symbol;Acc:HGNC:17284]",{"v":1.963292,"d":"1.96"},{"v":0.309673,"d":"0.31"},{"v":6.33988755881204,"d":"6.34"},{"v":2.66445725364816,"d":"2.66"},{"v":0.000489667240239642,"d":"0.00"},{"v":0.0127326351509357,"d":"0.01"},"up","yes"]
[169360,0,"chr6","-",134169284,134174842,"ENST00000367855",11,2422,"MSTRG.13288","SGK1","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016607(nuclear speck);GO:0016020(membrane);GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0005829(cytosol);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005739(mitochondrion);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0006915(apoptotic process);GO:0035556(intracellular signal transduction);GO:0034220(ion transmembrane transport);GO:0004712(protein serine/threonine/tyrosine kinase activity);GO:0005246(calcium channel regulator activity);GO:0015459(potassium channel regulator activity);GO:0017080(sodium channel regulator activity);GO:0017081(chloride channel regulator activity);GO:0001558(regulation of cell growth);GO:0006814(sodium ion transport);GO:0006950(response to stress);GO:0006974(cellular response to DNA damage stimulus);GO:0007616(long-term memory);GO:0008217(regulation of blood pressure);GO:0018105(peptidyl-serine phosphorylation);GO:0030334(regulation of cell migration);GO:0032411(positive regulation of transporter activity);GO:0042127(regulation of cell proliferation);GO:0042981(regulation of apoptotic process);GO:0048812(neuron projection morphogenesis);GO:0050790(regulation of catalytic activity);GO:0051090(regulation of sequence-specific DNA binding transcription factor activity);GO:0060453(regulation of gastric acid secretion);GO:0070294(renal sodium ion absorption);GO:0035091(phosphatidylinositol binding)","04068(FoxO signaling pathway);04151(PI3K-Akt signaling pathway);04150(mTOR signaling pathway);04960(Aldosterone-regulated sodium reabsorption)","NA","NA","serum/glucocorticoid regulated kinase 1 [Source:HGNC Symbol;Acc:HGNC:10810]",{"v":5.45435,"d":"5.45"},{"v":0.881289,"d":"0.88"},{"v":6.18905943453283,"d":"6.19"},{"v":2.62972017644451,"d":"2.63"},{"v":0.000492601053657016,"d":"0.00"},{"v":0.0127921124012664,"d":"0.01"},"up","yes"]
[137954,0,"chr3","-",69169990,69386073,"ENST00000398540",23,5060,"ENSG00000114541","FRMD4B","GO:0005737(cytoplasm);GO:0005856(cytoskeleton);GO:0005615(extracellular space);GO:0090162(establishment of epithelial cell polarity);GO:0001726(ruffle)","NA","NA","NA","FERM domain containing 4B [Source:HGNC Symbol;Acc:HGNC:24886]",{"v":1.745459,"d":"1.75"},{"v":0.276716,"d":"0.28"},{"v":6.30776319403287,"d":"6.31"},{"v":2.65712849950584,"d":"2.66"},{"v":0.000494961030837937,"d":"0.00"},{"v":0.0128365516097262,"d":"0.01"},"up","yes"]
[78839,0,"chr17","+",7484366,7514616,"ENST00000617998",29,6751,"MSTRG.6400","POLR2A","GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0016740(transferase activity);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0006366(transcription from RNA polymerase II promoter);GO:0005665(DNA-directed RNA polymerase II, core complex);GO:0006351(transcription, DNA-templated);GO:0005515(protein binding);GO:0003899(DNA-directed 5'-3' RNA polymerase activity);GO:0016779(nucleotidyltransferase activity);GO:0005654(nucleoplasm);GO:0006368(transcription elongation from RNA polymerase II promoter);GO:0006370(7-methylguanosine mRNA capping);GO:0050434(positive regulation of viral transcription);GO:0006367(transcription initiation from RNA polymerase II promoter);GO:0042795(snRNA transcription from RNA polymerase II promoter);GO:0006353(DNA-templated transcription, termination);GO:0000398(mRNA splicing, via spliceosome);GO:0031625(ubiquitin protein ligase binding);GO:0060964(regulation of gene silencing by miRNA);GO:0006283(transcription-coupled nucleotide-excision repair);GO:0008543(fibroblast growth factor receptor signaling pathway);GO:0016070(RNA metabolic process);GO:0035019(somatic stem cell population maintenance);GO:0033120(positive regulation of RNA splicing);GO:0000974(Prp19 complex);GO:0001055(RNA polymerase II activity);GO:0003968(RNA-directed 5'-3' RNA polymerase activity);GO:0001172(transcription, RNA-templated)","NA","NA","NA","RNA polymerase II subunit A [Source:HGNC Symbol;Acc:HGNC:9187]",{"v":27.290363,"d":"27.29"},{"v":4.515451,"d":"4.52"},{"v":6.04377347910541,"d":"6.04"},{"v":2.59544958924274,"d":"2.60"},{"v":0.000496488004210677,"d":"0.00"},{"v":0.0128449759538567,"d":"0.01"},"up","yes"]
[20889,"j","chr10","+",69087280,69104818,"MSTRG.1749.4",4,1686,"MSTRG.1749","SRGN","NA","NA","NA","NA","NA",{"v":298.542236,"d":"298.54"},{"v":49.445023,"d":"49.45"},{"v":6.03786221314934,"d":"6.04"},{"v":2.59403783424897,"d":"2.59"},{"v":0.00049658412192745,"d":"0.00"},{"v":0.0128449759538567,"d":"0.01"},"up","yes"]
[136394,"j","chr3","+",49674489,49683511,"MSTRG.10939.13",20,2218,"MSTRG.10939","APEH","NA","NA","NA","NA","NA",{"v":1.962381,"d":"1.96"},{"v":9.084998,"d":"9.08"},{"v":0.216002359053904,"d":"0.22"},{"v":-2.21088102612462,"d":"-2.21"},{"v":0.000497757098541169,"d":"0.00"},{"v":0.0128585084411653,"d":"0.01"},"down","yes"]
[195934,0,"chrX","+",17686782,17735978,"ENST00000615422",9,8860,"ENSG00000188158","NHS","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005794(Golgi apparatus);GO:0005886(plasma membrane);GO:0030054(cell junction);GO:0042995(cell projection);GO:0016604(nuclear body);GO:0005925(focal adhesion);GO:0005923(bicellular tight junction);GO:0030027(lamellipodium);GO:0030154(cell differentiation);GO:0016324(apical plasma membrane);GO:0002088(lens development in camera-type eye)","NA","NA","NA","NHS actin remodeling regulator [Source:HGNC Symbol;Acc:HGNC:7820]",{"v":0.902755,"d":"0.90"},{"v":0.143462,"d":"0.14"},{"v":6.2926419539669,"d":"6.29"},{"v":2.65366585711118,"d":"2.65"},{"v":0.000508273662464502,"d":"0.00"},{"v":0.0131065162860203,"d":"0.01"},"up","yes"]
[80069,0,"chr17","+",17476986,17493226,"ENST00000268711",2,2228,"ENSG00000141026","MED9","GO:0005634(nucleus);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0001104(RNA polymerase II transcription cofactor activity);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0016592(mediator complex);GO:0005515(protein binding)","NA","NA","NA","mediator complex subunit 9 [Source:HGNC Symbol;Acc:HGNC:25487]",{"v":2.78083,"d":"2.78"},{"v":0.431406,"d":"0.43"},{"v":6.44596968980496,"d":"6.45"},{"v":2.68839740458255,"d":"2.69"},{"v":0.000508682257310671,"d":"0.00"},{"v":0.0131065162860203,"d":"0.01"},"up","yes"]
[142022,0,"chr3","-",157149287,157160178,"ENST00000477127",11,1464,"MSTRG.11297","CCNL1","GO:0005634(nucleus);GO:0006396(RNA processing);GO:0016607(nuclear speck);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0005515(protein binding);GO:0019901(protein kinase binding);GO:0005654(nucleoplasm);GO:0000079(regulation of cyclin-dependent protein serine/threonine kinase activity);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0016538(cyclin-dependent protein serine/threonine kinase regulator activity);GO:0045737(positive regulation of cyclin-dependent protein serine/threonine kinase activity);GO:1901409(positive regulation of phosphorylation of RNA polymerase II C-terminal domain);GO:0000307(cyclin-dependent protein kinase holoenzyme complex)","NA","NA","NA","cyclin L1 [Source:HGNC Symbol;Acc:HGNC:20569]",{"v":1.544665,"d":"1.54"},{"v":7.257234,"d":"7.26"},{"v":0.212844866239672,"d":"0.21"},{"v":-2.2321258017604,"d":"-2.23"},{"v":0.00051124286822835,"d":"0.00"},{"v":0.0131546327665094,"d":"0.01"},"down","yes"]
[42204,"j","chr12","+",53452311,53475553,"MSTRG.3414.24",13,1758,"MSTRG.3414","PCBP2","NA","NA","NA","NA","NA",{"v":8.756272,"d":"8.76"},{"v":1.418172,"d":"1.42"},{"v":6.17433710438508,"d":"6.17"},{"v":2.62628425288305,"d":"2.63"},{"v":0.000511879281898737,"d":"0.00"},{"v":0.0131546327665094,"d":"0.01"},"up","yes"]
[83041,0,"chr17","+",40062899,40092627,"ENST00000450525",9,4895,"MSTRG.6801","THRA","GO:0005634(nucleus);GO:0008270(zinc ion binding);GO:0006355(regulation of transcription, DNA-templated);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0043565(sequence-specific DNA binding);GO:0046872(metal ion binding);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0030522(intracellular receptor signaling pathway);GO:0007165(signal transduction);GO:0004887(thyroid hormone receptor activity);GO:0005829(cytosol);GO:0005515(protein binding);GO:0003707(steroid hormone receptor activity);GO:0043401(steroid hormone mediated signaling pathway);GO:0005654(nucleoplasm);GO:0006366(transcription from RNA polymerase II promoter);GO:0019904(protein domain specific binding);GO:0008134(transcription factor binding);GO:0045892(negative regulation of transcription, DNA-templated);GO:0006367(transcription initiation from RNA polymerase II promoter);GO:0044212(transcription regulatory region DNA binding);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0017055(negative regulation of RNA polymerase II transcriptional preinitiation complex assembly);GO:0070324(thyroid hormone binding);GO:0017025(TBP-class protein binding);GO:0009755(hormone-mediated signaling pathway);GO:2000143(negative regulation of DNA-templated transcription, initiation);GO:0000976(transcription regulatory region sequence-specific DNA binding);GO:0002153(steroid receptor RNA activator RNA binding);GO:0003727(single-stranded RNA binding);GO:0004879(RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding);GO:0031490(chromatin DNA binding);GO:0032403(protein complex binding);GO:0001502(cartilage condensation);GO:0001503(ossification);GO:0002155(regulation of thyroid hormone mediated signaling pathway);GO:0007611(learning or memory);GO:0008016(regulation of heart contraction);GO:0008050(female courtship behavior);GO:0009409(response to cold);GO:0009887(animal organ morphogenesis);GO:0010831(positive regulation of myotube differentiation);GO:0030218(erythrocyte differentiation);GO:0030878(thyroid gland development);GO:0033032(regulation of myeloid cell apoptotic process);GO:0042994(cytoplasmic sequestering of transcription factor);GO:0045925(positive regulation of female receptivity);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0050994(regulation of lipid catabolic process);GO:0060509(Type I pneumocyte differentiation);GO:0005737(cytoplasm)","04080(Neuroactive ligand-receptor interaction);04919(Thyroid hormone signaling pathway)","K05547","NA","thyroid hormone receptor, alpha [Source:HGNC Symbol;Acc:HGNC:11796]",{"v":1.426009,"d":"1.43"},{"v":0.22648,"d":"0.23"},{"v":6.2964014482515,"d":"6.30"},{"v":2.65452752765255,"d":"2.65"},{"v":0.00051307430661161,"d":"0.00"},{"v":0.0131682417370046,"d":"0.01"},"up","yes"]
[18822,0,"chr10","-",16593313,16817463,"ENST00000377911",8,955,"MSTRG.1593","RSU1","GO:0005515(protein binding);GO:0005925(focal adhesion);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0043547(positive regulation of GTPase activity);GO:0007165(signal transduction);GO:0010811(positive regulation of cell-substrate adhesion)","NA","NA","NA","Ras suppressor protein 1 [Source:HGNC Symbol;Acc:HGNC:10464]",{"v":3.108374,"d":"3.11"},{"v":14.450885,"d":"14.45"},{"v":0.215099213646777,"d":"0.22"},{"v":-2.2169258442778,"d":"-2.22"},{"v":0.000520218939774923,"d":"0.00"},{"v":0.0133218855432965,"d":"0.01"},"down","yes"]
[29555,0,"chr11","+",59144779,59155036,"ENST00000361723",4,3592,"ENSG00000166801","FAM111A","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0001650(fibrillar center);GO:0006260(DNA replication);GO:0051607(defense response to virus);GO:0005515(protein binding);GO:0045071(negative regulation of viral genome replication);GO:0016032(viral process);GO:0000785(chromatin)","NA","NA","NA","family with sequence similarity 111 member A [Source:HGNC Symbol;Acc:HGNC:24725]",{"v":2.764653,"d":"2.76"},{"v":0.444813,"d":"0.44"},{"v":6.21531519987051,"d":"6.22"},{"v":2.635827557128,"d":"2.64"},{"v":0.000520407192488793,"d":"0.00"},{"v":0.0133218855432965,"d":"0.01"},"up","yes"]
[63147,0,"chr15","-",59662865,59689443,"ENST00000612191",10,2515,"MSTRG.5146","BNIP2","GO:0001824(blastocyst development);GO:0007098(centrosome cycle);GO:0043410(positive regulation of MAPK cascade);GO:0045666(positive regulation of neuron differentiation);GO:0051057(positive regulation of small GTPase mediated signal transduction);GO:0051146(striated muscle cell differentiation);GO:0005814(centriole);GO:0031616(spindle pole centrosome);GO:0005737(cytoplasm);GO:0043547(positive regulation of GTPase activity);GO:0005515(protein binding);GO:0006915(apoptotic process);GO:0048471(perinuclear region of cytoplasm);GO:0005509(calcium ion binding);GO:0005829(cytosol);GO:0043231(intracellular membrane-bounded organelle);GO:0043066(negative regulation of apoptotic process);GO:0005635(nuclear envelope);GO:0005096(GTPase activator activity);GO:0051149(positive regulation of muscle cell differentiation);GO:0042802(identical protein binding);GO:0016020(membrane);GO:0016021(integral component of membrane)","NA","NA","NA","BCL2 interacting protein 2 [Source:HGNC Symbol;Acc:HGNC:1083]",{"v":0.445644,"d":"0.45"},{"v":2.134104,"d":"2.13"},{"v":0.20882018870683,"d":"0.21"},{"v":-2.2596668966806,"d":"-2.26"},{"v":0.000524979712645607,"d":"0.00"},{"v":0.0134215743589551,"d":"0.01"},"down","yes"]
[30855,0,"chr11","-",64764606,64778747,"ENST00000227503",13,2850,"MSTRG.2520","SF1","GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0006397(mRNA processing);GO:0008380(RNA splicing);GO:0005634(nucleus);GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0005654(nucleoplasm);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0005840(ribosome);GO:0005515(protein binding);GO:0005681(spliceosomal complex);GO:0045131(pre-mRNA branch point binding);GO:0000398(mRNA splicing, via spliceosome);GO:1903507(negative regulation of nucleic acid-templated transcription);GO:0042802(identical protein binding);GO:0003714(transcription corepressor activity);GO:0000245(spliceosomal complex assembly);GO:0000389(mRNA 3'-splice site recognition);GO:0030238(male sex determination);GO:0030575(nuclear body organization);GO:0033327(Leydig cell differentiation);GO:0048662(negative regulation of smooth muscle cell proliferation);GO:0050810(regulation of steroid biosynthetic process);GO:0016604(nuclear body)","NA","NA","NA","splicing factor 1 [Source:HGNC Symbol;Acc:HGNC:12950]",{"v":1.377717,"d":"1.38"},{"v":6.347439,"d":"6.35"},{"v":0.217050845230651,"d":"0.22"},{"v":-2.20389505420076,"d":"-2.20"},{"v":0.000530337673661939,"d":"0.00"},{"v":0.0135410604986096,"d":"0.01"},"down","yes"]
[9450,0,"chr1","+",113929710,113977804,"ENST00000369558",16,8157,"MSTRG.815","HIPK1","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0005813(centrosome);GO:0005515(protein binding);GO:0001654(eye development);GO:0097191(extrinsic apoptotic signaling pathway);GO:1901796(regulation of signal transduction by p53 class mediator);GO:0045766(positive regulation of angiogenesis);GO:0060216(definitive hemopoiesis);GO:0072577(endothelial cell apoptotic process);GO:0010803(regulation of tumor necrosis factor-mediated signaling pathway);GO:0007224(smoothened signaling pathway);GO:0008284(positive regulation of cell proliferation);GO:0009952(anterior/posterior pattern specification);GO:0010842(retina layer formation);GO:0030182(neuron differentiation);GO:0034333(adherens junction assembly);GO:0042771(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator);GO:0048596(embryonic camera-type eye morphogenesis);GO:0060059(embryonic retina morphogenesis in camera-type eye);GO:0060235(lens induction in camera-type eye);GO:0061072(iris morphogenesis);GO:0016605(PML body);GO:0016607(nuclear speck);GO:0003677(DNA binding)","04218(Cellular senescence)","K08826","EC:2.7.11.1","homeodomain interacting protein kinase 1 [Source:HGNC Symbol;Acc:HGNC:19006]",{"v":21.566103,"d":"21.57"},{"v":3.606148,"d":"3.61"},{"v":5.98037102193254,"d":"5.98"},{"v":2.58023499193136,"d":"2.58"},{"v":0.000536330138071826,"d":"0.00"},{"v":0.0136764185208316,"d":"0.01"},"up","yes"]
[118239,0,"chr2","+",203014879,203219874,"ENST00000449802",55,10938,"MSTRG.9373","NBEAL1","NA","NA","NA","NA","neurobeachin like 1 [Source:HGNC Symbol;Acc:HGNC:20681]",{"v":0.581167,"d":"0.58"},{"v":0.091423,"d":"0.09"},{"v":6.35690143618127,"d":"6.36"},{"v":2.66832371960398,"d":"2.67"},{"v":5.38339095220217E-4,"d":"0.00"},{"v":0.0137099794288515,"d":"0.01"},"up","yes"]
[186204,0,"chr8","-",102253736,102412689,"ENST00000220959",59,9418,"ENSG00000104517","UBR5","GO:0003723(RNA binding);GO:0008270(zinc ion binding);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0016740(transferase activity);GO:0016567(protein ubiquitination);GO:0004842(ubiquitin-protein transferase activity);GO:0043130(ubiquitin binding);GO:0005634(nucleus);GO:0090263(positive regulation of canonical Wnt signaling pathway);GO:0016020(membrane);GO:0046872(metal ion binding);GO:0005515(protein binding);GO:0006281(DNA repair);GO:0006974(cellular response to DNA damage stimulus);GO:0043234(protein complex);GO:0008283(cell proliferation);GO:0006511(ubiquitin-dependent protein catabolic process);GO:0000209(protein polyubiquitination);GO:0034450(ubiquitin-ubiquitin ligase activity);GO:0010628(positive regulation of gene expression);GO:0033160(positive regulation of protein import into nucleus, translocation);GO:0035413(positive regulation of catenin import into nucleus);GO:0050847(progesterone receptor signaling pathway);GO:1901315(negative regulation of histone H2A K63-linked ubiquitination);GO:2000780(negative regulation of double-strand break repair);GO:0048471(perinuclear region of cytoplasm)","04120(Ubiquitin mediated proteolysis)","K10593","EC:2.3.2.26","ubiquitin protein ligase E3 component n-recognin 5 [Source:HGNC Symbol;Acc:HGNC:16806]",{"v":1.15496,"d":"1.15"},{"v":0.18678,"d":"0.19"},{"v":6.18353142734768,"d":"6.18"},{"v":2.628430999558,"d":"2.63"},{"v":0.000544599257422654,"d":"0.00"},{"v":0.0138515811129556,"d":"0.01"},"up","yes"]
[139435,0,"chr3","+",119294373,119420714,"ENST00000264245",12,9317,"ENSG00000031081","ARHGAP31","GO:0007165(signal transduction);GO:0043547(positive regulation of GTPase activity);GO:0042995(cell projection);GO:0030054(cell junction);GO:0005096(GTPase activator activity);GO:0005925(focal adhesion);GO:0005829(cytosol);GO:0030027(lamellipodium);GO:0051056(regulation of small GTPase mediated signal transduction);GO:0007264(small GTPase mediated signal transduction);GO:0017124(SH3 domain binding)","NA","NA","NA","Rho GTPase activating protein 31 [Source:HGNC Symbol;Acc:HGNC:29216]",{"v":2.304747,"d":"2.30"},{"v":0.37997,"d":"0.38"},{"v":6.06560254756955,"d":"6.07"},{"v":2.60065096755716,"d":"2.60"},{"v":0.000548137254201516,"d":"0.00"},{"v":0.0139236713557633,"d":"0.01"},"up","yes"]
[86986,"j","chr17","-",64499342,64503823,"MSTRG.7113.2",9,2893,"MSTRG.7113","DDX5","NA","NA","NA","NA","NA",{"v":2.088793,"d":"2.09"},{"v":0.327958,"d":"0.33"},{"v":6.36908689527317,"d":"6.37"},{"v":2.67108655519957,"d":"2.67"},{"v":5.48916208355408E-4,"d":"0.00"},{"v":0.0139255819627395,"d":"0.01"},"up","yes"]
[79884,"j","chr17","+",16438993,16441570,"MSTRG.6464.7",4,751,"MSTRG.6464","LRRC75A-AS1","NA","NA","NA","NA","NA",{"v":8.736958,"d":"8.74"},{"v":39.814106,"d":"39.81"},{"v":0.219443782060559,"d":"0.22"},{"v":-2.18807670287384,"d":"-2.19"},{"v":0.000551949924753657,"d":"0.00"},{"v":0.0139846160192386,"d":"0.01"},"down","yes"]
[160794,"j","chr5","+",163505587,163519309,"MSTRG.12524.5",6,1936,"MSTRG.12524","MAT2B","NA","NA","NA","NA","NA",{"v":2.409266,"d":"2.41"},{"v":10.991713,"d":"10.99"},{"v":0.219189311074625,"d":"0.22"},{"v":-2.18975064894125,"d":"-2.19"},{"v":0.000553806310249674,"d":"0.00"},{"v":0.0140083372043431,"d":"0.01"},"down","yes"]
[50076,0,"chr13","-",45333471,45341284,"ENST00000616577",6,4814,"MSTRG.3983","TPT1","GO:0003723(RNA binding);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005515(protein binding);GO:0006816(calcium ion transport);GO:0005509(calcium ion binding);GO:0070062(extracellular exosome);GO:0008017(microtubule binding);GO:0009615(response to virus);GO:0030154(cell differentiation);GO:0042981(regulation of apoptotic process);GO:0043066(negative regulation of apoptotic process);GO:0005615(extracellular space);GO:0005634(nucleus);GO:0006874(cellular calcium ion homeostasis);GO:0045298(tubulin complex);GO:1902230(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage);GO:0005771(multivesicular body)","NA","NA","NA","tumor protein, translationally-controlled 1 [Source:HGNC Symbol;Acc:HGNC:12022]",{"v":6.487,"d":"6.49"},{"v":29.252649,"d":"29.25"},{"v":0.221757694491189,"d":"0.22"},{"v":-2.17294393123276,"d":"-2.17"},{"v":0.000554302002779494,"d":"0.00"},{"v":0.0140083372043431,"d":"0.01"},"down","yes"]
[49400,0,"chr13","-",30202630,30307484,"ENST00000380615",11,7551,"ENSG00000102781","KATNAL1","GO:0005737(cytoplasm);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0016787(hydrolase activity);GO:0051301(cell division);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0007049(cell cycle);GO:0008017(microtubule binding);GO:0005874(microtubule);GO:0008568(microtubule-severing ATPase activity);GO:0051013(microtubule severing);GO:0000922(spindle pole);GO:0005813(centrosome);GO:0005815(microtubule organizing center);GO:0005819(spindle);GO:0030496(midbody);GO:0005634(nucleus);GO:0042802(identical protein binding);GO:0016887(ATPase activity)","NA","NA","NA","katanin catalytic subunit A1 like 1 [Source:HGNC Symbol;Acc:HGNC:28361]",{"v":0.638532,"d":"0.64"},{"v":0.098975,"d":"0.10"},{"v":6.45144733518565,"d":"6.45"},{"v":2.68962285496325,"d":"2.69"},{"v":0.000558722729143256,"d":"0.00"},{"v":0.014102047658529,"d":"0.01"},"up","yes"]
[200813,0,"chrX","+",152917865,152973480,"ENST00000318529",15,3878,"MSTRG.15483","ZNF185","GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0051015(actin filament binding);GO:0015629(actin cytoskeleton);GO:0005856(cytoskeleton);GO:0030054(cell junction);GO:0005925(focal adhesion);GO:0008270(zinc ion binding)","NA","NA","NA","zinc finger protein 185 with LIM domain [Source:HGNC Symbol;Acc:HGNC:12976]",{"v":3.048674,"d":"3.05"},{"v":0.495898,"d":"0.50"},{"v":6.14778442340965,"d":"6.15"},{"v":2.62006657675109,"d":"2.62"},{"v":0.000560996304172031,"d":"0.00"},{"v":0.014141394734976,"d":"0.01"},"up","yes"]
[8496,0,"chr1","+",101236888,101241518,"ENST00000305352",2,2909,"MSTRG.734","S1PR1","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0043231(intracellular membrane-bounded organelle);GO:0004930(G-protein coupled receptor activity);GO:0007186(G-protein coupled receptor signaling pathway);GO:0005654(nucleoplasm);GO:0005886(plasma membrane);GO:0004871(signal transducer activity);GO:0007165(signal transduction);GO:0038036(sphingosine-1-phosphate receptor activity);GO:0045121(membrane raft);GO:0006935(chemotaxis);GO:0005768(endosome);GO:0030500(regulation of bone mineralization);GO:0072678(T cell migration);GO:0007155(cell adhesion);GO:0031226(intrinsic component of plasma membrane);GO:0030032(lamellipodium assembly);GO:0001664(G-protein coupled receptor binding);GO:0016477(cell migration);GO:0001525(angiogenesis);GO:0031532(actin cytoskeleton reorganization);GO:0003376(sphingosine-1-phosphate signaling pathway);GO:0045124(regulation of bone resorption);GO:0001955(blood vessel maturation);GO:0046625(sphingolipid binding);GO:0003245(cardiac muscle tissue growth involved in heart morphogenesis);GO:0007193(adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway);GO:0007420(brain development);GO:0008284(positive regulation of cell proliferation);GO:0019226(transmission of nerve impulse);GO:0030155(regulation of cell adhesion);GO:0030182(neuron differentiation);GO:0030335(positive regulation of cell migration);GO:0030595(leukocyte chemotaxis);GO:0043547(positive regulation of GTPase activity);GO:0045446(endothelial cell differentiation);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0048661(positive regulation of smooth muscle cell proliferation);GO:0050927(positive regulation of positive chemotaxis);GO:0051482(positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway);GO:0051497(negative regulation of stress fiber assembly);GO:0061384(heart trabecula morphogenesis);GO:0009897(external side of plasma membrane)","04068(FoxO signaling pathway);04071(Sphingolipid signaling pathway);04080(Neuroactive ligand-receptor interaction)","K04288","NA","sphingosine-1-phosphate receptor 1 [Source:HGNC Symbol;Acc:HGNC:3165]",{"v":0.434371,"d":"0.43"},{"v":2.040184,"d":"2.04"},{"v":0.212907757339534,"d":"0.21"},{"v":-2.2316995792381,"d":"-2.23"},{"v":0.000564785831332096,"d":"0.00"},{"v":0.0142188066544523,"d":"0.01"},"down","yes"]
[195971,0,"chrX","+",18507097,18638407,"ENST00000623535",17,12533,"ENSG00000008086","CDKL5","GO:0005634(nucleus);GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0043547(positive regulation of GTPase activity);GO:0001764(neuron migration);GO:0044294(dendritic growth cone);GO:0032587(ruffle membrane);GO:0048365(Rac GTPase binding);GO:0045773(positive regulation of axon extension);GO:0046777(protein autophosphorylation);GO:0050773(regulation of dendrite development);GO:0050775(positive regulation of dendrite morphogenesis);GO:0032839(dendrite cytoplasm);GO:0060999(positive regulation of dendritic spine development);GO:0045202(synapse);GO:0048471(perinuclear region of cytoplasm)","NA","NA","NA","cyclin dependent kinase like 5 [Source:HGNC Symbol;Acc:HGNC:11411]",{"v":1.124281,"d":"1.12"},{"v":0.184611,"d":"0.18"},{"v":6.09000005416795,"d":"6.09"},{"v":2.60644224096377,"d":"2.61"},{"v":0.000565846853346035,"d":"0.00"},{"v":0.0142274174510945,"d":"0.01"},"up","yes"]
[113723,0,"chr2","+",113236237,113267010,"ENST00000445745",5,2570,"ENSG00000189223","PAX8-AS1","NA","NA","NA","NA","PAX8 antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:49271]",{"v":2.871225,"d":"2.87"},{"v":0.461441,"d":"0.46"},{"v":6.22230144265464,"d":"6.22"},{"v":2.63744828868274,"d":"2.64"},{"v":0.000566913984968702,"d":"0.00"},{"v":0.0142361598154323,"d":"0.01"},"up","yes"]
[45327,0,"chr12","+",95217746,95302790,"ENST00000436874",12,4562,"ENSG00000028203","VEZT","GO:0005634(nucleus);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0005886(plasma membrane);GO:0016337(single organismal cell-cell adhesion);GO:0030054(cell junction);GO:0031410(cytoplasmic vesicle);GO:0017022(myosin binding);GO:0005912(adherens junction);GO:0001669(acrosomal vesicle)","NA","NA","NA","vezatin, adherens junctions transmembrane protein [Source:HGNC Symbol;Acc:HGNC:18258]",{"v":0.306096,"d":"0.31"},{"v":1.436428,"d":"1.44"},{"v":0.213095261300949,"d":"0.21"},{"v":-2.23042958329482,"d":"-2.23"},{"v":0.000569229186807822,"d":"0.00"},{"v":0.0142761814303589,"d":"0.01"},"down","yes"]
[125097,0,"chr20","+",59191020,59259110,"ENST00000371030",5,9401,"ENSG00000124203","ZNF831","GO:0003676(nucleic acid binding);GO:0046872(metal ion binding);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0005634(nucleus);GO:0007165(signal transduction);GO:0007275(multicellular organism development);GO:0043565(sequence-specific DNA binding);GO:0044212(transcription regulatory region DNA binding);GO:0001206(transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding);GO:0006366(transcription from RNA polymerase II promoter)","NA","NA","NA","zinc finger protein 831 [Source:HGNC Symbol;Acc:HGNC:16167]",{"v":0.14657,"d":"0.15"},{"v":0.688394,"d":"0.69"},{"v":0.212915859231777,"d":"0.21"},{"v":-2.23164468064015,"d":"-2.23"},{"v":5.75542672510587E-4,"d":"0.00"},{"v":0.0143860111190072,"d":"0.01"},"down","yes"]
[61971,0,"chr15","-",44573357,44663678,"ENST00000558319",32,6426,"MSTRG.5048","SPG11","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005730(nucleolus);GO:0005829(cytosol);GO:0005765(lysosomal membrane);GO:0005886(plasma membrane);GO:0042995(cell projection);GO:0005515(protein binding);GO:0045202(synapse);GO:0030425(dendrite);GO:0030424(axon);GO:0070062(extracellular exosome);GO:0007268(chemical synaptic transmission);GO:0031410(cytoplasmic vesicle);GO:0048489(synaptic vesicle transport);GO:0008088(axo-dendritic transport);GO:0007040(lysosome organization);GO:0048675(axon extension);GO:0090389(phagosome-lysosome fusion involved in apoptotic cell clearance);GO:0090659(walking behavior)","NA","NA","NA","SPG11, spatacsin vesicle trafficking associated [Source:HGNC Symbol;Acc:HGNC:11226]",{"v":2.076628,"d":"2.08"},{"v":0.340792,"d":"0.34"},{"v":6.09353505950844,"d":"6.09"},{"v":2.60727942570034,"d":"2.61"},{"v":0.000575952634021373,"d":"0.00"},{"v":0.0143860111190072,"d":"0.01"},"up","yes"]
[178045,0,"chr7","+",116862600,116918188,"ENST00000426421",10,1214,"MSTRG.13928","CAPZA2","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0003779(actin binding);GO:0051016(barbed-end actin filament capping);GO:0051693(actin filament capping);GO:0008290(F-actin capping protein complex);GO:0005576(extracellular region);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0005903(brush border);GO:0030863(cortical cytoskeleton);GO:0045087(innate immune response);GO:0019886(antigen processing and presentation of exogenous peptide antigen via MHC class II);GO:0006888(ER to Golgi vesicle-mediated transport);GO:0006461(protein complex assembly);GO:0006928(movement of cell or subcellular component);GO:0015629(actin cytoskeleton);GO:0007596(blood coagulation)","04144(Endocytosis)","NA","NA","capping actin protein of muscle Z-line alpha subunit 2 [Source:HGNC Symbol;Acc:HGNC:1490]",{"v":5.973244,"d":"5.97"},{"v":26.979174,"d":"26.98"},{"v":0.221402034028173,"d":"0.22"},{"v":-2.17525961861759,"d":"-2.18"},{"v":0.000576214935467877,"d":"0.00"},{"v":0.0143860111190072,"d":"0.01"},"down","yes"]
[1465,0,"chr1","+",11012400,11026420,"ENST00000240185",6,5367,"MSTRG.156","TARDBP","GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0005634(nucleus);GO:0003730(mRNA 3'-UTR binding);GO:0006397(mRNA processing);GO:0008380(RNA splicing);GO:0005654(nucleoplasm);GO:0006366(transcription from RNA polymerase II promoter);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0001205(transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding);GO:0032024(positive regulation of insulin secretion);GO:0034976(response to endoplasmic reticulum stress);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0005726(perichromatin fibrils);GO:0005737(cytoplasm);GO:0016607(nuclear speck);GO:0035061(interchromatin granule);GO:0042802(identical protein binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0003690(double-stranded DNA binding);GO:0070935(3'-UTR-mediated mRNA stabilization);GO:0010629(negative regulation of gene expression);GO:0051726(regulation of cell cycle);GO:0001933(negative regulation of protein phosphorylation);GO:0042981(regulation of apoptotic process);GO:0043922(negative regulation by host of viral transcription);GO:0071765(nuclear inner membrane organization)","NA","NA","NA","TAR DNA binding protein [Source:HGNC Symbol;Acc:HGNC:11571]",{"v":8.69597,"d":"8.70"},{"v":1.458623,"d":"1.46"},{"v":5.96176667994403,"d":"5.96"},{"v":2.57573991503482,"d":"2.58"},{"v":0.000576516414866219,"d":"0.00"},{"v":0.0143860111190072,"d":"0.01"},"up","yes"]
[175776,0,"chr7","+",87345695,87399795,"ENST00000331536",18,3175,"ENSG00000005469","CROT","GO:0006810(transport);GO:0043231(intracellular membrane-bounded organelle);GO:0016740(transferase activity);GO:0016746(transferase activity, transferring acyl groups);GO:0006629(lipid metabolic process);GO:0006631(fatty acid metabolic process);GO:0005777(peroxisome);GO:0005102(receptor binding);GO:0005782(peroxisomal matrix);GO:0033540(fatty acid beta-oxidation using acyl-CoA oxidase);GO:0006635(fatty acid beta-oxidation);GO:0006091(generation of precursor metabolites and energy);GO:0009437(carnitine metabolic process);GO:0008458(carnitine O-octanoyltransferase activity);GO:0015908(fatty acid transport);GO:0015936(coenzyme A metabolic process);GO:0051791(medium-chain fatty acid metabolic process);GO:0005739(mitochondrion)","04146(Peroxisome)","K05940","EC:2.3.1.137","carnitine O-octanoyltransferase [Source:HGNC Symbol;Acc:HGNC:2366]",{"v":0.419206,"d":"0.42"},{"v":1.960752,"d":"1.96"},{"v":0.213798583400654,"d":"0.21"},{"v":-2.22567580089173,"d":"-2.23"},{"v":0.000578775280879212,"d":"0.00"},{"v":0.0144195937331078,"d":"0.01"},"down","yes"]
[51014,0,"chr13","-",77044655,77326679,"ENST00000544440",83,14664,"MSTRG.4036","MYCBP2","GO:0005634(nucleus);GO:0016020(membrane);GO:0046872(metal ion binding);GO:0016740(transferase activity);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0016567(protein ubiquitination);GO:0005515(protein binding);GO:0004842(ubiquitin-protein transferase activity)","NA","NA","NA","MYC binding protein 2, E3 ubiquitin protein ligase [Source:HGNC Symbol;Acc:HGNC:23386]",{"v":8.980325,"d":"8.98"},{"v":1.517724,"d":"1.52"},{"v":5.91696843431349,"d":"5.92"},{"v":2.56485819865716,"d":"2.56"},{"v":0.000579319639065126,"d":"0.00"},{"v":0.0144195937331078,"d":"0.01"},"up","yes"]
[51956,0,"chr13","-",113177611,113208666,"ENST00000375477",15,1654,"MSTRG.4113","PCID2","GO:0005515(protein binding);GO:0045893(positive regulation of transcription, DNA-templated);GO:0003690(double-stranded DNA binding);GO:0003723(RNA binding);GO:0005575(cellular_component);GO:0006368(transcription elongation from RNA polymerase II promoter);GO:0005643(nuclear pore);GO:0043066(negative regulation of apoptotic process);GO:0090267(positive regulation of mitotic cell cycle spindle assembly checkpoint);GO:0048536(spleen development);GO:2000117(negative regulation of cysteine-type endopeptidase activity);GO:0043488(regulation of mRNA stability);GO:0000973(posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery);GO:0035327(transcriptionally active chromatin);GO:0016973(poly(A)+ mRNA export from nucleus);GO:0071033(nuclear retention of pre-mRNA at the site of transcription);GO:0070390(transcription export complex 2);GO:0045579(positive regulation of B cell differentiation)","NA","NA","NA","PCI domain containing 2 [Source:HGNC Symbol;Acc:HGNC:25653]",{"v":0.641971,"d":"0.64"},{"v":3.049447,"d":"3.05"},{"v":0.210520464858055,"d":"0.21"},{"v":-2.24796760927204,"d":"-2.25"},{"v":0.000581436232176819,"d":"0.00"},{"v":0.0144277718573041,"d":"0.01"},"down","yes"]
[51469,0,"chr13","-",99254714,99258428,"ENST00000397470",2,1468,"MSTRG.4055","GPR18","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0004930(G-protein coupled receptor activity);GO:0007186(G-protein coupled receptor signaling pathway);GO:0005886(plasma membrane);GO:0004871(signal transducer activity);GO:0007165(signal transduction);GO:0030659(cytoplasmic vesicle membrane);GO:0031410(cytoplasmic vesicle);GO:0005887(integral component of plasma membrane);GO:0002300(CD8-positive, alpha-beta intraepithelial T cell differentiation);GO:0002305(CD8-positive, gamma-delta intraepithelial T cell differentiation);GO:0002689(negative regulation of leukocyte chemotaxis);GO:0032720(negative regulation of tumor necrosis factor production);GO:0035025(positive regulation of Rho protein signal transduction);GO:0051482(positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway);GO:0030217(T cell differentiation)","NA","NA","NA","G protein-coupled receptor 18 [Source:HGNC Symbol;Acc:HGNC:4472]",{"v":2.09306,"d":"2.09"},{"v":9.554597,"d":"9.55"},{"v":0.219063137880122,"d":"0.22"},{"v":-2.19058135483903,"d":"-2.19"},{"v":0.000581692069462113,"d":"0.00"},{"v":0.0144277718573041,"d":"0.01"},"down","yes"]
[22801,0,"chr10","-",100150094,100188334,"ENST00000421367",11,5792,"MSTRG.1906","ERLIN1","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005783(endoplasmic reticulum);GO:0006629(lipid metabolic process);GO:0005789(endoplasmic reticulum membrane);GO:0008202(steroid metabolic process);GO:0005515(protein binding);GO:0031625(ubiquitin protein ligase binding);GO:0008203(cholesterol metabolic process);GO:0030433(ubiquitin-dependent ERAD pathway);GO:0008289(lipid binding);GO:0055085(transmembrane transport);GO:0043234(protein complex);GO:0015485(cholesterol binding);GO:0032933(SREBP signaling pathway);GO:0045541(negative regulation of cholesterol biosynthetic process);GO:0045717(negative regulation of fatty acid biosynthetic process)","NA","NA","NA","ER lipid raft associated 1 [Source:HGNC Symbol;Acc:HGNC:16947]",{"v":0.252353,"d":"0.25"},{"v":1.181181,"d":"1.18"},{"v":0.213644648872611,"d":"0.21"},{"v":-2.22671491239503,"d":"-2.23"},{"v":0.000581835553978609,"d":"0.00"},{"v":0.0144277718573041,"d":"0.01"},"down","yes"]
[173232,0,"chr7","-",36854361,37449249,"ENST00000310758",22,4022,"MSTRG.13575","ELMO1","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005886(plasma membrane);GO:0043547(positive regulation of GTPase activity);GO:0030036(actin cytoskeleton organization);GO:0005515(protein binding);GO:0006915(apoptotic process);GO:0016477(cell migration);GO:0038096(Fc-gamma receptor signaling pathway involved in phagocytosis);GO:0006909(phagocytosis);GO:0005829(cytosol);GO:0017124(SH3 domain binding);GO:0048010(vascular endothelial growth factor receptor signaling pathway);GO:0050690(regulation of defense response to virus by virus);GO:0048870(cell motility);GO:0006911(phagocytosis, engulfment);GO:0016601(Rac protein signal transduction);GO:0005085(guanyl-nucleotide exchange factor activity);GO:0032045(guanyl-nucleotide exchange factor complex);GO:0030029(actin filament-based process)","04062(Chemokine signaling pathway);05131(Shigellosis);05100(Bacterial invasion of epithelial cells)","K12366","NA","engulfment and cell motility 1 [Source:HGNC Symbol;Acc:HGNC:16286]",{"v":12.998122,"d":"13.00"},{"v":2.187905,"d":"2.19"},{"v":5.9408987136096,"d":"5.94"},{"v":2.57068119223699,"d":"2.57"},{"v":5.83530310612298E-4,"d":"0.00"},{"v":0.0144516868415471,"d":"0.01"},"up","yes"]
[146821,0,"chr4","-",39455811,39458931,"ENST00000511075",5,1028,"MSTRG.11579","RPL9","GO:0005634(nucleus);GO:0016020(membrane);GO:0006412(translation);GO:0030529(intracellular ribonucleoprotein complex);GO:0005622(intracellular);GO:0003735(structural constituent of ribosome);GO:0005840(ribosome);GO:0005515(protein binding);GO:0019843(rRNA binding);GO:0005925(focal adhesion);GO:0005829(cytosol);GO:0031012(extracellular matrix);GO:0002181(cytoplasmic translation);GO:0006413(translational initiation);GO:0003723(RNA binding);GO:0006364(rRNA processing);GO:0000184(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay);GO:0019083(viral transcription);GO:0006614(SRP-dependent cotranslational protein targeting to membrane);GO:0022625(cytosolic large ribosomal subunit)","03010(Ribosome)","NA","NA","ribosomal protein L9 [Source:HGNC Symbol;Acc:HGNC:10369]",{"v":6.402412,"d":"6.40"},{"v":28.850512,"d":"28.85"},{"v":0.22191675489156,"d":"0.22"},{"v":-2.17190949861683,"d":"-2.17"},{"v":5.84465720885227E-4,"d":"0.00"},{"v":0.0144567596060961,"d":"0.01"},"down","yes"]
[73658,0,"chr16","+",57668317,57689378,"ENST00000567991",11,2317,"MSTRG.5962","ADGRG3","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0004930(G-protein coupled receptor activity);GO:0007186(G-protein coupled receptor signaling pathway);GO:0005886(plasma membrane);GO:0004871(signal transducer activity);GO:0007165(signal transduction);GO:0004888(transmembrane signaling receptor activity);GO:0007166(cell surface receptor signaling pathway);GO:0043312(neutrophil degranulation);GO:0035579(specific granule membrane);GO:0030334(regulation of cell migration);GO:1901223(negative regulation of NIK/NF-kappaB signaling);GO:0030183(B cell differentiation);GO:0032792(negative regulation of CREB transcription factor activity)","NA","NA","NA","adhesion G protein-coupled receptor G3 [Source:HGNC Symbol;Acc:HGNC:13728]",{"v":15.827344,"d":"15.83"},{"v":2.658774,"d":"2.66"},{"v":5.95287301590884,"d":"5.95"},{"v":2.5735861197528,"d":"2.57"},{"v":0.000587489306663481,"d":"0.00"},{"v":0.0145013785337743,"d":"0.01"},"up","yes"]
[55884,"j","chr14","+",64703935,64750602,"MSTRG.4476.1",18,10625,"MSTRG.4476","PLEKHG3","NA","NA","NA","NA","NA",{"v":1.382908,"d":"1.38"},{"v":6.194318,"d":"6.19"},{"v":0.223254279163582,"d":"0.22"},{"v":-2.16324026682457,"d":"-2.16"},{"v":0.000587735273099203,"d":"0.00"},{"v":0.0145013785337743,"d":"0.01"},"down","yes"]
[119474,0,"chr2","-",219374196,219387932,"ENST00000373966",15,1875,"MSTRG.9440","DNPEP","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0005829(cytosol);GO:0016787(hydrolase activity);GO:0005515(protein binding);GO:0008233(peptidase activity);GO:0006508(proteolysis);GO:0008237(metallopeptidase activity);GO:0004177(aminopeptidase activity);GO:0042802(identical protein binding);GO:0072562(blood microparticle);GO:0070006(metalloaminopeptidase activity);GO:0006518(peptide metabolic process)","NA","NA","NA","aspartyl aminopeptidase [Source:HGNC Symbol;Acc:HGNC:2981]",{"v":1.416871,"d":"1.42"},{"v":6.471552,"d":"6.47"},{"v":0.2189383628533,"d":"0.22"},{"v":-2.19140332607424,"d":"-2.19"},{"v":0.000589380999922944,"d":"0.00"},{"v":0.0145238745037051,"d":"0.01"},"down","yes"]
[190063,"j","chr9","-",35696893,35728557,"MSTRG.14757.1",57,10284,"MSTRG.14757","TLN1","NA","NA","NA","NA","NA",{"v":10.252105,"d":"10.25"},{"v":1.735717,"d":"1.74"},{"v":5.9065533148549,"d":"5.91"},{"v":2.56231651177259,"d":"2.56"},{"v":0.000590257056555696,"d":"0.00"},{"v":0.0145273714367215,"d":"0.01"},"up","yes"]
[123110,0,"chr20","-",34714775,34825630,"ENST00000612493",14,4082,"MSTRG.9679","NCOA6","GO:0005634(nucleus);GO:0043231(intracellular membrane-bounded organelle);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0005515(protein binding);GO:0006281(DNA repair);GO:0006310(DNA recombination);GO:0006260(DNA replication);GO:0003713(transcription coactivator activity);GO:0030374(ligand-dependent nuclear receptor transcription coactivator activity);GO:0045893(positive regulation of transcription, DNA-templated);GO:0006367(transcription initiation from RNA polymerase II promoter);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0007507(heart development);GO:0030331(estrogen receptor binding);GO:0003682(chromatin binding);GO:0019899(enzyme binding);GO:0035097(histone methyltransferase complex);GO:0006352(DNA-templated transcription, initiation);GO:0007420(brain development);GO:0030520(intracellular estrogen receptor signaling pathway);GO:0042921(glucocorticoid receptor signaling pathway);GO:0019216(regulation of lipid metabolic process);GO:0006974(cellular response to DNA damage stimulus);GO:0005667(transcription factor complex);GO:0046966(thyroid hormone receptor binding);GO:0009725(response to hormone);GO:0046965(retinoid X receptor binding);GO:0030099(myeloid cell differentiation)","NA","NA","NA","nuclear receptor coactivator 6 [Source:HGNC Symbol;Acc:HGNC:15936]",{"v":0.18122,"d":"0.18"},{"v":0.883192,"d":"0.88"},{"v":0.20518754698865,"d":"0.21"},{"v":-2.28498491970697,"d":"-2.28"},{"v":0.000591340335160512,"d":"0.00"},{"v":0.0145322741726088,"d":"0.01"},"down","yes"]
[185724,0,"chr8","-",94925972,94949411,"ENST00000342697",4,5638,"MSTRG.14468","TP53INP1","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0010506(regulation of autophagy);GO:0006915(apoptotic process);GO:0006914(autophagy);GO:0031410(cytoplasmic vesicle);GO:0098869(cellular oxidant detoxification);GO:0008285(negative regulation of cell proliferation);GO:0045893(positive regulation of transcription, DNA-templated);GO:0005515(protein binding);GO:0005654(nucleoplasm);GO:0010508(positive regulation of autophagy);GO:0000045(autophagosome assembly);GO:0007050(cell cycle arrest);GO:0005776(autophagosome);GO:0042981(regulation of apoptotic process);GO:1901796(regulation of signal transduction by p53 class mediator);GO:0016605(PML body);GO:0030336(negative regulation of cell migration);GO:0006950(response to stress);GO:0016209(antioxidant activity);GO:0048102(autophagic cell death);GO:0009408(response to heat);GO:0010628(positive regulation of gene expression);GO:0010629(negative regulation of gene expression);GO:0034644(cellular response to UV);GO:0043065(positive regulation of apoptotic process);GO:0048147(negative regulation of fibroblast proliferation);GO:0071361(cellular response to ethanol);GO:0071447(cellular response to hydroperoxide);GO:0072703(cellular response to methyl methanesulfonate);GO:1904761(negative regulation of myofibroblast differentiation);GO:2001235(positive regulation of apoptotic signaling pathway)","05166(HTLV-I infection)","K15310","NA","tumor protein p53 inducible nuclear protein 1 [Source:HGNC Symbol;Acc:HGNC:18022]",{"v":0.660133,"d":"0.66"},{"v":3.004036,"d":"3.00"},{"v":0.219748698084843,"d":"0.22"},{"v":-2.18607347683201,"d":"-2.19"},{"v":0.000592224559231743,"d":"0.00"},{"v":0.0145322741726088,"d":"0.01"},"down","yes"]
[156561,"j","chr5","-",88722601,88883375,"MSTRG.12209.22",10,1868,"MSTRG.12209","MEF2C","NA","NA","NA","NA","NA",{"v":9.84588,"d":"9.85"},{"v":1.64371,"d":"1.64"},{"v":5.99003473848793,"d":"5.99"},{"v":2.58256436977515,"d":"2.58"},{"v":0.000592659453067276,"d":"0.00"},{"v":0.0145322741726088,"d":"0.01"},"up","yes"]
[67266,0,"chr16","-",85801,138670,"ENST00000621703",11,2812,"MSTRG.5474","NPRL3","GO:0016020(membrane);GO:0005765(lysosomal membrane);GO:0043547(positive regulation of GTPase activity);GO:0005096(GTPase activator activity);GO:0005764(lysosome);GO:0003674(molecular_function);GO:0008150(biological_process);GO:0005575(cellular_component);GO:2000785(regulation of autophagosome assembly);GO:0032007(negative regulation of TOR signaling);GO:0034198(cellular response to amino acid starvation);GO:1990130(GATOR1 complex);GO:0038202(TORC1 signaling);GO:0003281(ventricular septum development);GO:0035909(aorta morphogenesis);GO:0048738(cardiac muscle tissue development);GO:0060021(palate development)","04150(mTOR signaling pathway)","NA","NA","NPR3 like, GATOR1 complex subunit [Source:HGNC Symbol;Acc:HGNC:14124]",{"v":3.159947,"d":"3.16"},{"v":0.514804,"d":"0.51"},{"v":6.13815549218732,"d":"6.14"},{"v":2.61780519271971,"d":"2.62"},{"v":5.95162591687119E-4,"d":"0.00"},{"v":0.0145731381512712,"d":"0.01"},"up","yes"]
[187715,"j","chr8","-",141207173,141308153,"MSTRG.14598.2",9,7905,"MSTRG.14598","SLC45A4","NA","NA","NA","NA","NA",{"v":10.960151,"d":"10.96"},{"v":1.856827,"d":"1.86"},{"v":5.90262366930252,"d":"5.90"},{"v":2.5613563635137,"d":"2.56"},{"v":0.000595798906629191,"d":"0.00"},{"v":0.0145731381512712,"d":"0.01"},"up","yes"]
[3919,0,"chr1","+",32651142,32680053,"ENST00000414241",12,1788,"MSTRG.383","RBBP4","GO:0005634(nucleus);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0016569(covalent chromatin modification);GO:0016575(histone deacetylation);GO:0000790(nuclear chromatin);GO:0005515(protein binding);GO:0007049(cell cycle);GO:0006260(DNA replication);GO:0043234(protein complex);GO:0035098(ESC/E(Z) complex);GO:0034080(CENP-A containing nucleosome assembly);GO:1901796(regulation of signal transduction by p53 class mediator);GO:0004407(histone deacetylase activity);GO:0008285(negative regulation of cell proliferation);GO:0006335(DNA replication-dependent nucleosome assembly);GO:0006336(DNA replication-independent nucleosome assembly);GO:0042826(histone deacetylase binding);GO:0045814(negative regulation of gene expression, epigenetic);GO:0016589(NURF complex);GO:0031492(nucleosomal DNA binding);GO:0016580(Sin3 complex);GO:0043044(ATP-dependent chromatin remodeling);GO:0016581(NuRD complex);GO:0051726(regulation of cell cycle);GO:0042393(histone binding);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:0000980(RNA polymerase II distal enhancer sequence-specific DNA binding);GO:0031497(chromatin assembly);GO:0008094(DNA-dependent ATPase activity);GO:0006338(chromatin remodeling);GO:0033186(CAF-1 complex);GO:0060416(response to growth hormone)","04218(Cellular senescence)","K10752","NA","RB binding protein 4, chromatin remodeling factor [Source:HGNC Symbol;Acc:HGNC:9887]",{"v":1.625102,"d":"1.63"},{"v":7.425557,"d":"7.43"},{"v":0.218852538604175,"d":"0.22"},{"v":-2.191968976113,"d":"-2.19"},{"v":0.000598583470635823,"d":"0.00"},{"v":0.0146231724900514,"d":"0.01"},"down","yes"]
[76899,0,"chr16","-",89267630,89490561,"ENST00000301030",13,9301,"MSTRG.6242","ANKRD11","GO:0005634(nucleus);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0005886(plasma membrane);GO:0042475(odontogenesis of dentin-containing tooth);GO:0048705(skeletal system morphogenesis);GO:0060325(face morphogenesis);GO:0001701(in utero embryonic development);GO:0001894(tissue homeostasis);GO:0035264(multicellular organism growth);GO:0060323(head morphogenesis);GO:0060348(bone development)","NA","NA","NA","ankyrin repeat domain 11 [Source:HGNC Symbol;Acc:HGNC:21316]",{"v":7.557203,"d":"7.56"},{"v":1.280761,"d":"1.28"},{"v":5.90055677835287,"d":"5.90"},{"v":2.56085109404556,"d":"2.56"},{"v":0.000599666497516849,"d":"0.00"},{"v":0.0146315667729512,"d":"0.01"},"up","yes"]
[1447,0,"chr1","-",10636604,10796648,"ENST00000377022",21,7936,"ENSG00000130940","CASZ1","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0043231(intracellular membrane-bounded organelle);GO:0046872(metal ion binding);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0007275(multicellular organism development);GO:0045893(positive regulation of transcription, DNA-templated);GO:0045664(regulation of neuron differentiation)","NA","NA","NA","castor zinc finger 1 [Source:HGNC Symbol;Acc:HGNC:26002]",{"v":0.807477,"d":"0.81"},{"v":0.129661,"d":"0.13"},{"v":6.22760120622238,"d":"6.23"},{"v":2.63867656223548,"d":"2.64"},{"v":0.000601650616848812,"d":"0.00"},{"v":0.0146510591339282,"d":"0.01"},"up","yes"]
[124805,0,"chr20","+",56412261,56460387,"ENST00000434344",5,2888,"MSTRG.9843","CASS4","GO:0005737(cytoplasm);GO:0007155(cell adhesion);GO:0005856(cytoskeleton);GO:0030054(cell junction);GO:0005925(focal adhesion)","NA","NA","NA","Cas scaffolding protein family member 4 [Source:HGNC Symbol;Acc:HGNC:15878]",{"v":2.435614,"d":"2.44"},{"v":0.393648,"d":"0.39"},{"v":6.18728915172946,"d":"6.19"},{"v":2.62930745726147,"d":"2.63"},{"v":0.000601946183337558,"d":"0.00"},{"v":0.0146510591339282,"d":"0.01"},"up","yes"]
[166438,0,"chr6","+",45422485,45551079,"ENST00000359524",7,5390,"ENSG00000124813","RUNX2","GO:0030509(BMP signaling pathway);GO:0005634(nucleus);GO:0005524(ATP binding);GO:0005654(nucleoplasm);GO:0006355(regulation of transcription, DNA-templated);GO:0006366(transcription from RNA polymerase II promoter);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0005515(protein binding);GO:0045893(positive regulation of transcription, DNA-templated);GO:0000981(RNA polymerase II transcription factor activity, sequence-specific DNA binding);GO:0030182(neuron differentiation);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0001503(ossification);GO:0071773(cellular response to BMP stimulus);GO:0045892(negative regulation of transcription, DNA-templated);GO:0000790(nuclear chromatin);GO:1901522(positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus);GO:0001649(osteoblast differentiation);GO:0030097(hemopoiesis);GO:0002062(chondrocyte differentiation);GO:0045595(regulation of cell differentiation);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:0000979(RNA polymerase II core promoter sequence-specific DNA binding);GO:0001077(transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0003682(chromatin binding);GO:0019904(protein domain specific binding);GO:0043425(bHLH transcription factor binding);GO:0044212(transcription regulatory region DNA binding);GO:0070491(repressing transcription factor binding);GO:0001501(skeletal system development);GO:0001958(endochondral ossification);GO:0002051(osteoblast fate commitment);GO:0002063(chondrocyte development);GO:0002076(osteoblast development);GO:0008284(positive regulation of cell proliferation);GO:0010628(positive regulation of gene expression);GO:0030217(T cell differentiation);GO:0030278(regulation of ossification);GO:0032332(positive regulation of chondrocyte differentiation);GO:0035115(embryonic forelimb morphogenesis);GO:0040036(regulation of fibroblast growth factor receptor signaling pathway);GO:0042475(odontogenesis of dentin-containing tooth);GO:0042487(regulation of odontogenesis of dentin-containing tooth);GO:0045667(regulation of osteoblast differentiation);GO:0045669(positive regulation of osteoblast differentiation);GO:0045879(negative regulation of smoothened signaling pathway);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0048469(cell maturation);GO:0048701(embryonic cranial skeleton morphogenesis);GO:0048705(skeletal system morphogenesis);GO:0048863(stem cell differentiation);GO:0005667(transcription factor complex);GO:0005737(cytoplasm)","05202(Transcriptional misregulation in cancers)","NA","NA","runt related transcription factor 2 [Source:HGNC Symbol;Acc:HGNC:10472]",{"v":4.756265,"d":"4.76"},{"v":0.799187,"d":"0.80"},{"v":5.95137933925352,"d":"5.95"},{"v":2.57322407771096,"d":"2.57"},{"v":0.000603386792982789,"d":"0.00"},{"v":0.01466808090853,"d":"0.01"},"up","yes"]
[171332,0,"chr7","-",2234291,2242198,"ENST00000242257",3,1601,"MSTRG.13450","MRM2","GO:0008168(methyltransferase activity);GO:0016740(transferase activity);GO:0001510(RNA methylation);GO:0032259(methylation);GO:0005739(mitochondrion);GO:0005730(nucleolus);GO:0006364(rRNA processing);GO:0005759(mitochondrial matrix);GO:0008283(cell proliferation);GO:0000451(rRNA 2'-O-methylation);GO:0008650(rRNA (uridine-2'-O-)-methyltransferase activity);GO:0031167(rRNA methylation)","NA","NA","NA","mitochondrial rRNA methyltransferase 2 [Source:HGNC Symbol;Acc:HGNC:16352]",{"v":4.173335,"d":"4.17"},{"v":0.67142,"d":"0.67"},{"v":6.21568466831491,"d":"6.22"},{"v":2.63591331536118,"d":"2.64"},{"v":0.00060568184680969,"d":"0.00"},{"v":0.0147058066069572,"d":"0.01"},"up","yes"]
[65956,0,"chr15","+",84782654,84806430,"ENST00000299927",8,7863,"MSTRG.5388","ZNF592","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0005515(protein binding)","NA","NA","NA","zinc finger protein 592 [Source:HGNC Symbol;Acc:HGNC:28986]",{"v":0.097655,"d":"0.10"},{"v":0.473844,"d":"0.47"},{"v":0.206091034180026,"d":"0.21"},{"v":-2.27864635189943,"d":"-2.28"},{"v":0.000608396075097604,"d":"0.00"},{"v":0.014750352373935,"d":"0.01"},"down","yes"]
[30536,0,"chr11","+",63681446,63759882,"ENST00000341307",6,2524,"MSTRG.2489","RTN3","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005783(endoplasmic reticulum);GO:0005794(Golgi apparatus);GO:0005789(endoplasmic reticulum membrane);GO:0005515(protein binding);GO:0006915(apoptotic process);GO:0000139(Golgi membrane);GO:0005886(plasma membrane);GO:0016192(vesicle-mediated transport);GO:0070062(extracellular exosome);GO:0016032(viral process);GO:0005615(extracellular space);GO:0071786(endoplasmic reticulum tubular network organization);GO:0071787(endoplasmic reticulum tubular network formation)","05010(Alzheimer's disease)","K20723","NA","reticulon 3 [Source:HGNC Symbol;Acc:HGNC:10469]",{"v":3.009135,"d":"3.01"},{"v":0.489889,"d":"0.49"},{"v":6.14248329723672,"d":"6.14"},{"v":2.6188220295876,"d":"2.62"},{"v":0.000609007372625069,"d":"0.00"},{"v":0.014750352373935,"d":"0.01"},"up","yes"]
[149995,"j","chr4","-",108047765,108166988,"MSTRG.11788.5",12,2697,"MSTRG.11788","LEF1","NA","NA","NA","NA","NA",{"v":8.833488,"d":"8.83"},{"v":1.481928,"d":"1.48"},{"v":5.9608078125253,"d":"5.96"},{"v":2.57550785890068,"d":"2.58"},{"v":0.000611430031516862,"d":"0.00"},{"v":0.0147909259946891,"d":"0.01"},"up","yes"]
[161600,"j","chr5","-",177483422,177497646,"MSTRG.12580.5",13,2487,"MSTRG.12580","PDLIM7","NA","NA","NA","NA","NA",{"v":5.854314,"d":"5.85"},{"v":0.971942,"d":"0.97"},{"v":6.02331620611106,"d":"6.02"},{"v":2.59055799808973,"d":"2.59"},{"v":0.000618682670521042,"d":"0.00"},{"v":0.0149480985155926,"d":"0.01"},"up","yes"]
[71740,0,"chr16","+",30065777,30070380,"ENST00000395240",9,1447,"MSTRG.5821","ALDOA","GO:0070062(extracellular exosome);GO:0008360(regulation of cell shape);GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005829(cytosol);GO:0003824(catalytic activity);GO:0004332(fructose-bisphosphate aldolase activity);GO:0016829(lyase activity);GO:0006096(glycolytic process);GO:0005515(protein binding);GO:0005615(extracellular space);GO:0005576(extracellular region);GO:0045296(cadherin binding);GO:0031430(M band);GO:0031674(I band);GO:0043312(neutrophil degranulation);GO:0015629(actin cytoskeleton);GO:0002576(platelet degranulation);GO:0034774(secretory granule lumen);GO:1904813(ficolin-1-rich granule lumen);GO:0031093(platelet alpha granule lumen);GO:1904724(tertiary granule lumen);GO:0051289(protein homotetramerization);GO:0006094(gluconeogenesis);GO:0061621(canonical glycolysis);GO:0042802(identical protein binding);GO:0003779(actin binding);GO:0006754(ATP biosynthetic process);GO:0046716(muscle cell cellular homeostasis);GO:0008092(cytoskeletal protein binding);GO:0015631(tubulin binding);GO:0070061(fructose binding);GO:0006000(fructose metabolic process);GO:0006941(striated muscle contraction);GO:0007015(actin filament organization);GO:0030388(fructose 1,6-bisphosphate metabolic process);GO:0016021(integral component of membrane)","00010(Glycolysis / Gluconeogenesis);00030(Pentose phosphate pathway);00051(Fructose and mannose metabolism);04066(HIF-1 signaling pathway)","NA","NA","aldolase, fructose-bisphosphate A [Source:HGNC Symbol;Acc:HGNC:414]",{"v":7.305354,"d":"7.31"},{"v":32.573681,"d":"32.57"},{"v":0.224271675037279,"d":"0.22"},{"v":-2.15668067180456,"d":"-2.16"},{"v":0.000619662594059359,"d":"0.00"},{"v":0.0149535163551788,"d":"0.01"},"down","yes"]
[133515,0,"chr3","-",12839051,12841543,"ENST00000452606",3,631,"MSTRG.10672","RPL32","GO:0003723(RNA binding);GO:0016020(membrane);GO:0006412(translation);GO:0030529(intracellular ribonucleoprotein complex);GO:0005622(intracellular);GO:0003735(structural constituent of ribosome);GO:0005840(ribosome);GO:0071549(cellular response to dexamethasone stimulus);GO:0097421(liver regeneration);GO:0022625(cytosolic large ribosomal subunit);GO:0005829(cytosol);GO:0006413(translational initiation);GO:0006364(rRNA processing);GO:0000184(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay);GO:0019083(viral transcription);GO:0006614(SRP-dependent cotranslational protein targeting to membrane)","03010(Ribosome)","NA","NA","ribosomal protein L32 [Source:HGNC Symbol;Acc:HGNC:10336]",{"v":2.153501,"d":"2.15"},{"v":10.047902,"d":"10.05"},{"v":0.214323447820251,"d":"0.21"},{"v":-2.22213839977972,"d":"-2.22"},{"v":0.000621880119147175,"d":"0.00"},{"v":0.0149887500580807,"d":"0.01"},"down","yes"]
[98645,0,"chr19","+",18557888,18569297,"ENST00000595073",6,1095,"MSTRG.8000","KXD1","GO:0016020(membrane);GO:0005765(lysosomal membrane);GO:0005515(protein binding);GO:0005764(lysosome);GO:0016192(vesicle-mediated transport);GO:0032418(lysosome localization);GO:0031083(BLOC-1 complex);GO:0099078(BORC complex)","NA","NA","NA","KxDL motif containing 1 [Source:HGNC Symbol;Acc:HGNC:28420]",{"v":1.177196,"d":"1.18"},{"v":5.454179,"d":"5.45"},{"v":0.215833767098586,"d":"0.22"},{"v":-2.21200750339458,"d":"-2.21"},{"v":0.000625877135900848,"d":"0.00"},{"v":0.0150667357240949,"d":"0.02"},"down","yes"]
[198463,0,"chrX","-",77505713,77786216,"ENST00000395603",34,10218,"MSTRG.15376","ATRX","GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0005654(nucleoplasm);GO:0016787(hydrolase activity);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0016569(covalent chromatin modification);GO:0004386(helicase activity);GO:0032508(DNA duplex unwinding);GO:0003677(DNA binding);GO:0006334(nucleosome assembly);GO:0005694(chromosome);GO:0005515(protein binding);GO:0006281(DNA repair);GO:0006974(cellular response to DNA damage stimulus);GO:0016604(nuclear body);GO:0000781(chromosome, telomeric region);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0003682(chromatin binding);GO:0042393(histone binding);GO:0000212(meiotic spindle organization);GO:0007283(spermatogenesis);GO:0010571(positive regulation of nuclear cell cycle DNA replication);GO:0030330(DNA damage response, signal transduction by p53 class mediator);GO:0030900(forebrain development);GO:0031297(replication fork processing);GO:0032206(positive regulation of telomere maintenance);GO:0035128(post-embryonic forelimb morphogenesis);GO:0035264(multicellular organism growth);GO:0060009(Sertoli cell development);GO:0070192(chromosome organization involved in meiotic cell cycle);GO:0070198(protein localization to chromosome, telomeric region);GO:0072520(seminiferous tubule development);GO:0072711(cellular response to hydroxyurea);GO:1901581(negative regulation of telomeric RNA transcription from RNA pol II promoter);GO:0000228(nuclear chromosome);GO:0000780(condensed nuclear chromosome, centromeric region);GO:0000784(nuclear chromosome, telomeric region);GO:0000792(heterochromatin);GO:0005721(pericentric heterochromatin);GO:0016605(PML body);GO:0031618(nuclear pericentric heterochromatin);GO:0031933(telomeric heterochromatin);GO:0006338(chromatin remodeling);GO:0035064(methylated histone binding);GO:0006336(DNA replication-independent nucleosome assembly);GO:0006310(DNA recombination);GO:0003678(DNA helicase activity);GO:1904908(negative regulation of maintenance of mitotic sister chromatid cohesion, telomeric);GO:0006306(DNA methylation);GO:0070087(chromo shadow domain binding);GO:0005720(nuclear heterochromatin);GO:0015616(DNA translocase activity);GO:1900112(regulation of histone H3-K9 trimethylation);GO:1901582(positive regulation of telomeric RNA transcription from RNA pol II promoter);GO:0070603(SWI/SNF superfamily-type complex);GO:1990707(nuclear subtelomeric heterochromatin)","NA","NA","NA","ATRX, chromatin remodeler [Source:HGNC Symbol;Acc:HGNC:886]",{"v":2.685284,"d":"2.69"},{"v":0.454909,"d":"0.45"},{"v":5.90290365765461,"d":"5.90"},{"v":2.56142479549407,"d":"2.56"},{"v":0.000632010246449548,"d":"0.00"},{"v":0.0151958915634795,"d":"0.02"},"up","yes"]
[176841,0,"chr7","+",100205357,100221488,"ENST00000451963",9,3056,"MSTRG.13817","STAG3","GO:0005634(nucleus);GO:0005694(chromosome);GO:0007049(cell cycle);GO:0051321(meiotic cell cycle);GO:0005615(extracellular space);GO:0007059(chromosome segregation);GO:0000775(chromosome, centromeric region);GO:0000795(synaptonemal complex);GO:0030893(meiotic cohesin complex);GO:0007130(synaptonemal complex assembly);GO:0007129(synapsis);GO:0034502(protein localization to chromosome);GO:0000794(condensed nuclear chromosome);GO:0000800(lateral element);GO:0000802(transverse filament);GO:0001673(male germ cell nucleus);GO:0034991(nuclear meiotic cohesin complex)","04114(Oocyte meiosis)","NA","NA","stromal antigen 3 [Source:HGNC Symbol;Acc:HGNC:11356]",{"v":1.732658,"d":"1.73"},{"v":0.277744,"d":"0.28"},{"v":6.23832738060948,"d":"6.24"},{"v":2.64115926575926,"d":"2.64"},{"v":0.000638308066450597,"d":"0.00"},{"v":0.0153286893433549,"d":"0.02"},"up","yes"]
[94202,0,"chr19","+",1249888,1258699,"ENST00000591446",7,3243,"MSTRG.7602","MIDN","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005730(nucleolus);GO:0003674(molecular_function);GO:0008150(biological_process);GO:0019900(kinase binding);GO:0046676(negative regulation of insulin secretion);GO:0033132(negative regulation of glucokinase activity)","NA","NA","NA","midnolin [Source:HGNC Symbol;Acc:HGNC:16298]",{"v":0.261046,"d":"0.26"},{"v":1.250005,"d":"1.25"},{"v":0.208835964656141,"d":"0.21"},{"v":-2.25955790806082,"d":"-2.26"},{"v":0.000642655924630596,"d":"0.00"},{"v":0.0154102650885683,"d":"0.02"},"down","yes"]
[71870,0,"chr16","-",30350766,30355361,"ENST00000305596",7,3421,"MSTRG.5831","CD2BP2","GO:0005634(nucleus);GO:0006397(mRNA processing);GO:0008380(RNA splicing);GO:0005737(cytoplasm);GO:0016607(nuclear speck);GO:0005829(cytosol);GO:0001650(fibrillar center);GO:0005515(protein binding);GO:0005654(nucleoplasm);GO:0010923(negative regulation of phosphatase activity);GO:0000398(mRNA splicing, via spliceosome);GO:0043021(ribonucleoprotein complex binding);GO:0000244(spliceosomal tri-snRNP complex assembly);GO:0005682(U5 snRNP)","NA","NA","NA","CD2 cytoplasmic tail binding protein 2 [Source:HGNC Symbol;Acc:HGNC:1656]",{"v":3.799067,"d":"3.80"},{"v":16.818136,"d":"16.82"},{"v":0.22589108567085,"d":"0.23"},{"v":-2.14630075603868,"d":"-2.15"},{"v":6.43262530986326E-4,"d":"0.00"},{"v":0.0154102650885683,"d":"0.02"},"down","yes"]
[165732,0,"chr6","-",37482920,37499922,"ENST00000373408",4,619,"MSTRG.13004","CCDC167","GO:0016020(membrane);GO:0016021(integral component of membrane)","NA","NA","NA","coiled-coil domain containing 167 [Source:HGNC Symbol;Acc:HGNC:21239]",{"v":1.801415,"d":"1.80"},{"v":8.412321,"d":"8.41"},{"v":0.214140069072495,"d":"0.21"},{"v":-2.22337332231439,"d":"-2.22"},{"v":0.000645898405547931,"d":"0.00"},{"v":0.015454700905662,"d":"0.02"},"down","yes"]
[175026,0,"chr7","+",74209396,74229834,"ENST00000344995",13,2363,"MSTRG.13713","LAT2","GO:0042113(B cell activation);GO:0002764(immune response-regulating signaling pathway);GO:0005622(intracellular);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005886(plasma membrane);GO:0002376(immune system process);GO:0002250(adaptive immune response);GO:0038095(Fc-epsilon receptor signaling pathway);GO:0042629(mast cell granule);GO:0070062(extracellular exosome);GO:0005515(protein binding);GO:0043303(mast cell degranulation);GO:0019722(calcium-mediated signaling);GO:0035556(intracellular signal transduction);GO:0045121(membrane raft);GO:0042169(SH2 domain binding);GO:0050853(B cell receptor signaling pathway)","NA","NA","NA","linker for activation of T-cells family member 2 [Source:HGNC Symbol;Acc:HGNC:12749]",{"v":22.384096,"d":"22.38"},{"v":3.82567,"d":"3.83"},{"v":5.85102635616768,"d":"5.85"},{"v":2.54868971684574,"d":"2.55"},{"v":6.48558464361228E-4,"d":"0.00"},{"v":0.0154996073584299,"d":"0.02"},"up","yes"]
[7724,0,"chr1","-",86348738,86396340,"ENST00000370566",16,2155,"ENSG00000122417","ODF2L","GO:0005813(centrosome)","NA","NA","NA","outer dense fiber of sperm tails 2 like [Source:HGNC Symbol;Acc:HGNC:29225]",{"v":0.459408,"d":"0.46"},{"v":2.16151,"d":"2.16"},{"v":0.212540307470241,"d":"0.21"},{"v":-2.23419162599946,"d":"-2.23"},{"v":6.50745045469308E-4,"d":"0.00"},{"v":0.015505862589251,"d":"0.02"},"down","yes"]
[150577,0,"chr4","+",122324464,122362752,"ENST00000306802",24,4650,"MSTRG.11834","KIAA1109","GO:0005634(nucleus);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005515(protein binding);GO:0001558(regulation of cell growth);GO:0030856(regulation of epithelial cell differentiation)","NA","NA","NA","KIAA1109 [Source:HGNC Symbol;Acc:HGNC:26953]",{"v":0.633696,"d":"0.63"},{"v":2.850049,"d":"2.85"},{"v":0.222345650899335,"d":"0.22"},{"v":-2.169123909165,"d":"-2.17"},{"v":0.000651057356376488,"d":"0.00"},{"v":0.015505862589251,"d":"0.02"},"down","yes"]
[55944,"j","chr14","-",65075126,65102248,"MSTRG.4483.5",5,1940,"MSTRG.4483","MAX","NA","NA","NA","NA","NA",{"v":28.644863,"d":"28.64"},{"v":4.902578,"d":"4.90"},{"v":5.84281637130506,"d":"5.84"},{"v":2.54666394881222,"d":"2.55"},{"v":0.000652283921229092,"d":"0.00"},{"v":0.015505862589251,"d":"0.02"},"up","yes"]
[27228,0,"chr11","+",18396266,18408218,"ENST00000540430",8,2305,"MSTRG.2293","LDHA","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0003824(catalytic activity);GO:0006096(glycolytic process);GO:0005975(carbohydrate metabolic process);GO:0016616(oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor);GO:0005515(protein binding);GO:0019752(carboxylic acid metabolic process);GO:0004459(L-lactate dehydrogenase activity);GO:0005829(cytosol);GO:0045296(cadherin binding);GO:0070062(extracellular exosome);GO:0006090(pyruvate metabolic process);GO:0016021(integral component of membrane);GO:0004457(lactate dehydrogenase activity);GO:0019900(kinase binding);GO:0042802(identical protein binding);GO:0051287(NAD binding);GO:0001666(response to hypoxia);GO:0006089(lactate metabolic process);GO:0007584(response to nutrient);GO:0009749(response to glucose);GO:0014070(response to organic cyclic compound);GO:0019674(NAD metabolic process);GO:0042493(response to drug);GO:0042542(response to hydrogen peroxide);GO:0043065(positive regulation of apoptotic process);GO:0043627(response to estrogen);GO:0048569(post-embryonic animal organ development);GO:0051591(response to cAMP)","00010(Glycolysis / Gluconeogenesis);00620(Pyruvate metabolism);00640(Propanoate metabolism);00270(Cysteine and methionine metabolism);04066(HIF-1 signaling pathway);04922(Glucagon signaling pathway);05230(Central carbon metabolism in cancer)","K00016","EC:1.1.1.27","lactate dehydrogenase A [Source:HGNC Symbol;Acc:HGNC:6535]",{"v":0.65937,"d":"0.66"},{"v":3.024715,"d":"3.02"},{"v":0.217994092005362,"d":"0.22"},{"v":-2.19763905873866,"d":"-2.20"},{"v":0.000652526424655714,"d":"0.00"},{"v":0.015505862589251,"d":"0.02"},"down","yes"]
[120785,0,"chr2","-",239048169,239400949,"ENST00000543185",27,8990,"ENSG00000068024","HDAC4","GO:0008284(positive regulation of cell proliferation);GO:0051091(positive regulation of sequence-specific DNA binding transcription factor activity);GO:0010832(negative regulation of myotube differentiation);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0005737(cytoplasm);GO:0043433(negative regulation of sequence-specific DNA binding transcription factor activity);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0004407(histone deacetylase activity);GO:0016787(hydrolase activity);GO:0032041(NAD-dependent histone deacetylase activity (H3-K14 specific));GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0016569(covalent chromatin modification);GO:0006476(protein deacetylation);GO:0005515(protein binding);GO:0007399(nervous system development);GO:0006325(chromatin organization);GO:0006954(inflammatory response);GO:0001047(core promoter binding);GO:0016575(histone deacetylation);GO:0042113(B cell activation);GO:0000118(histone deacetylase complex);GO:0045893(positive regulation of transcription, DNA-templated);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0045892(negative regulation of transcription, DNA-templated);GO:0044212(transcription regulatory region DNA binding);GO:0006338(chromatin remodeling);GO:0014898(cardiac muscle hypertrophy in response to stress);GO:0042826(histone deacetylase binding);GO:0017053(transcriptional repressor complex);GO:0043565(sequence-specific DNA binding);GO:0070555(response to interleukin-1);GO:0008134(transcription factor binding);GO:0040029(regulation of gene expression, epigenetic);GO:0033235(positive regulation of protein sumoylation);GO:0008270(zinc ion binding);GO:0030955(potassium ion binding);GO:0030183(B cell differentiation);GO:0043393(regulation of protein binding);GO:0070491(repressing transcription factor binding);GO:0033613(activating transcription factor binding);GO:0001025(RNA polymerase III transcription factor binding);GO:0003677(DNA binding);GO:0003682(chromatin binding);GO:0003714(transcription corepressor activity);GO:0019901(protein kinase binding);GO:0033558(protein deacetylase activity);GO:0001501(skeletal system development);GO:0002076(osteoblast development);GO:0008285(negative regulation of cell proliferation);GO:0010592(positive regulation of lamellipodium assembly);GO:0010882(regulation of cardiac muscle contraction by calcium ion signaling);GO:0014894(response to denervation involved in regulation of muscle adaptation);GO:0014911(positive regulation of smooth muscle cell migration);GO:0034983(peptidyl-lysine deacetylation);GO:0042493(response to drug);GO:0043525(positive regulation of neuron apoptotic process);GO:0045668(negative regulation of osteoblast differentiation);GO:0045820(negative regulation of glycolytic process);GO:0048661(positive regulation of smooth muscle cell proliferation);GO:0048742(regulation of skeletal muscle fiber development);GO:0051153(regulation of striated muscle cell differentiation);GO:0070932(histone H3 deacetylation);GO:0070933(histone H4 deacetylation);GO:0071260(cellular response to mechanical stimulus);GO:0071356(cellular response to tumor necrosis factor);GO:0071374(cellular response to parathyroid hormone stimulus);GO:1902894(negative regulation of pri-miRNA transcription from RNA polymerase II promoter);GO:1903428(positive regulation of reactive oxygen species biosynthetic process);GO:0030017(sarcomere);GO:0030018(Z disc);GO:0031594(neuromuscular junction);GO:0031672(A band);GO:0042641(actomyosin);GO:0043234(protein complex)","04371(Apelin signaling pathway);05206(MicroRNAs in cancer);05203(Viral carcinogenesis);05034(Alcoholism);05169(Epstein-Barr virus infection);05165(Human papillomavirus infection)","K11406","EC:3.5.1.98","histone deacetylase 4 [Source:HGNC Symbol;Acc:HGNC:14063]",{"v":4.788303,"d":"4.79"},{"v":0.817701,"d":"0.82"},{"v":5.85581159861612,"d":"5.86"},{"v":2.5498691379603,"d":"2.55"},{"v":0.000652738201781185,"d":"0.00"},{"v":0.015505862589251,"d":"0.02"},"up","yes"]
[107546,0,"chr2","-",17663812,17753803,"ENST00000448223",28,5233,"MSTRG.8528","SMC6","GO:0005634(nucleus);GO:0016607(nuclear speck);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0005654(nucleoplasm);GO:0005694(chromosome);GO:0006281(DNA repair);GO:0005515(protein binding);GO:0006310(DNA recombination);GO:0006974(cellular response to DNA damage stimulus);GO:0000724(double-strand break repair via homologous recombination);GO:0030915(Smc5-Smc6 complex);GO:0000781(chromosome, telomeric region);GO:0031625(ubiquitin protein ligase binding);GO:0016605(PML body);GO:0090398(cellular senescence);GO:0005622(intracellular);GO:0035861(site of double-strand break);GO:0051984(positive regulation of chromosome segregation);GO:0000722(telomere maintenance via recombination);GO:0000803(sex chromosome);GO:0035061(interchromatin granule)","NA","NA","NA","structural maintenance of chromosomes 6 [Source:HGNC Symbol;Acc:HGNC:20466]",{"v":0.212184,"d":"0.21"},{"v":0.994449,"d":"0.99"},{"v":0.213368408032991,"d":"0.21"},{"v":-2.22858151267135,"d":"-2.23"},{"v":0.00065638950375208,"d":"0.00"},{"v":0.0155739034775134,"d":"0.02"},"down","yes"]
[89636,0,"chr17","-",82018703,82022918,"ENST00000392359",5,805,"ENSG00000169689","CENPX","GO:0006281(DNA repair);GO:0051382(kinetochore assembly);GO:0005634(nucleus);GO:0003677(DNA binding);GO:0051301(cell division);GO:0005694(chromosome);GO:0005515(protein binding);GO:0006974(cellular response to DNA damage stimulus);GO:0007049(cell cycle);GO:0043240(Fanconi anaemia nuclear complex);GO:0000775(chromosome, centromeric region);GO:0000776(kinetochore);GO:0000777(condensed chromosome kinetochore);GO:0005654(nucleoplasm);GO:0003690(double-stranded DNA binding);GO:0000712(resolution of meiotic recombination intermediates);GO:0031297(replication fork processing);GO:0031398(positive regulation of protein ubiquitination);GO:0034080(CENP-A containing nucleosome assembly);GO:0036297(interstrand cross-link repair);GO:0071821(FANCM-MHF complex)","03460(Fanconi anemia pathway)","K15360","NA","centromere protein X [Source:HGNC Symbol;Acc:HGNC:11422]",{"v":1.131907,"d":"1.13"},{"v":5.397191,"d":"5.40"},{"v":0.209721501425464,"d":"0.21"},{"v":-2.25345331542858,"d":"-2.25"},{"v":0.000659551693053636,"d":"0.00"},{"v":0.0156301903019705,"d":"0.02"},"down","yes"]
[119892,0,"chr2","-",229767441,229921999,"ENST00000389044",42,6405,"MSTRG.9465","TRIP12","GO:0005634(nucleus);GO:0016607(nuclear speck);GO:0016740(transferase activity);GO:0016567(protein ubiquitination);GO:0004842(ubiquitin-protein transferase activity);GO:0005515(protein binding);GO:0006281(DNA repair);GO:0006974(cellular response to DNA damage stimulus);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0061630(ubiquitin protein ligase activity);GO:0005829(cytosol);GO:0000209(protein polyubiquitination);GO:0042787(protein ubiquitination involved in ubiquitin-dependent protein catabolic process);GO:0009790(embryo development);GO:0046966(thyroid hormone receptor binding);GO:1901315(negative regulation of histone H2A K63-linked ubiquitination);GO:2000780(negative regulation of double-strand break repair)","04120(Ubiquitin mediated proteolysis)","K10590","EC:2.3.2.26","thyroid hormone receptor interactor 12 [Source:HGNC Symbol;Acc:HGNC:12306]",{"v":9.400473,"d":"9.40"},{"v":1.612266,"d":"1.61"},{"v":5.83059681218856,"d":"5.83"},{"v":2.54364356334291,"d":"2.54"},{"v":0.000661489221723032,"d":"0.00"},{"v":0.0156573549275782,"d":"0.02"},"up","yes"]
[41208,0,"chr12","-",49184796,49189324,"ENST00000301071",4,1915,"MSTRG.3349","TUBA1A","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005525(GTP binding);GO:0000166(nucleotide binding);GO:0003924(GTPase activity);GO:0015630(microtubule cytoskeleton);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0005200(structural constituent of cytoskeleton);GO:0007010(cytoskeleton organization);GO:0005874(microtubule);GO:0007017(microtubule-based process);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0055037(recycling endosome);GO:0000086(G2/M transition of mitotic cell cycle);GO:0010389(regulation of G2/M transition of mitotic cell cycle);GO:0097711(ciliary basal body docking);GO:0036464(cytoplasmic ribonucleoprotein granule);GO:0005198(structural molecule activity);GO:0030705(cytoskeleton-dependent intracellular transport);GO:0051301(cell division);GO:0019904(protein domain specific binding);GO:0005881(cytoplasmic microtubule);GO:0043209(myelin sheath);GO:0045121(membrane raft)","04145(Phagosome);04210(Apoptosis);04530(Tight junction);04540(Gap junction);05130(Pathogenic Escherichia coli infection)","K07374","NA","tubulin alpha 1a [Source:HGNC Symbol;Acc:HGNC:20766]",{"v":49.386692,"d":"49.39"},{"v":216.811905,"d":"216.81"},{"v":0.227785886572972,"d":"0.23"},{"v":-2.13424973327574,"d":"-2.13"},{"v":6.64324195293921E-4,"d":"0.00"},{"v":0.0157056716564828,"d":"0.02"},"down","yes"]
[88695,0,"chr17","+",78005056,78108835,"ENST00000301624",20,9632,"MSTRG.7276","TNRC6C","GO:0003676(nucleic acid binding);GO:0035278(miRNA mediated inhibition of translation);GO:0035195(gene silencing by miRNA);GO:0003723(RNA binding);GO:0005515(protein binding);GO:0031047(gene silencing by RNA);GO:0005829(cytosol);GO:0006417(regulation of translation);GO:0060213(positive regulation of nuclear-transcribed mRNA poly(A) tail shortening);GO:1900153(positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay);GO:0038111(interleukin-7-mediated signaling pathway);GO:0048015(phosphatidylinositol-mediated signaling);GO:0045652(regulation of megakaryocyte differentiation);GO:0007223(Wnt signaling pathway, calcium modulating pathway);GO:0035194(posttranscriptional gene silencing by RNA)","NA","NA","NA","trinucleotide repeat containing 6C [Source:HGNC Symbol;Acc:HGNC:29318]",{"v":0.611176,"d":"0.61"},{"v":0.099225,"d":"0.10"},{"v":6.15949609473419,"d":"6.16"},{"v":2.62281232959481,"d":"2.62"},{"v":0.000666616052997465,"d":"0.00"},{"v":0.0157346938112921,"d":"0.02"},"up","yes"]
[69491,0,"chr16","+",9092191,9113181,"ENST00000574285",3,10359,"MSTRG.5628","C16orf72","GO:0005515(protein binding)","NA","NA","NA","chromosome 16 open reading frame 72 [Source:HGNC Symbol;Acc:HGNC:30103]",{"v":13.709868,"d":"13.71"},{"v":2.364218,"d":"2.36"},{"v":5.79890179332024,"d":"5.80"},{"v":2.53577970586996,"d":"2.54"},{"v":0.000667546969093369,"d":"0.00"},{"v":0.0157346938112921,"d":"0.02"},"up","yes"]
[74266,0,"chr16","+",67109963,67147131,"ENST00000569600",17,1353,"MSTRG.6008","C16orf70","GO:0005515(protein binding)","NA","NA","NA","chromosome 16 open reading frame 70 [Source:HGNC Symbol;Acc:HGNC:29564]",{"v":4.51083,"d":"4.51"},{"v":0.731462,"d":"0.73"},{"v":6.16686854546101,"d":"6.17"},{"v":2.62453809378913,"d":"2.62"},{"v":0.000667937275191295,"d":"0.00"},{"v":0.0157346938112921,"d":"0.02"},"up","yes"]
[147247,0,"chr4","-",48497541,48557703,"ENST00000507873",30,7031,"MSTRG.11602","FRYL","GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0005938(cell cortex);GO:0000902(cell morphogenesis);GO:0031175(neuron projection development);GO:0090527(actin filament reorganization);GO:0030427(site of polarized growth)","NA","NA","NA","FRY like transcription coactivator [Source:HGNC Symbol;Acc:HGNC:29127]",{"v":0.30543,"d":"0.31"},{"v":1.375542,"d":"1.38"},{"v":0.222043383626236,"d":"0.22"},{"v":-2.17108651188151,"d":"-2.17"},{"v":0.000672587463171262,"d":"0.00"},{"v":0.0158253991929048,"d":"0.02"},"down","yes"]
[154587,0,"chr5","-",43289395,43313493,"ENST00000325110",11,3506,"ENSG00000112972","HMGCS1","GO:0005737(cytoplasm);GO:0016740(transferase activity);GO:0003824(catalytic activity);GO:0006629(lipid metabolic process);GO:0008152(metabolic process);GO:0004421(hydroxymethylglutaryl-CoA synthase activity);GO:0008144(drug binding);GO:0016853(isomerase activity);GO:0042803(protein homodimerization activity);GO:0043177(organic acid binding);GO:0001889(liver development);GO:0006694(steroid biosynthetic process);GO:0007420(brain development);GO:0008202(steroid metabolic process);GO:0008299(isoprenoid biosynthetic process);GO:0008584(male gonad development);GO:0009645(response to low light intensity stimulus);GO:0009725(response to hormone);GO:0010033(response to organic substance);GO:0010243(response to organonitrogen compound);GO:0014070(response to organic cyclic compound);GO:0014074(response to purine-containing compound);GO:0016126(sterol biosynthetic process);GO:0033197(response to vitamin E);GO:0034698(response to gonadotropin);GO:0042493(response to drug);GO:0046690(response to tellurium ion);GO:0055094(response to lipoprotein particle);GO:0070723(response to cholesterol);GO:0071372(cellular response to follicle-stimulating hormone stimulus);GO:0071397(cellular response to cholesterol);GO:0071407(cellular response to organic cyclic compound);GO:0005829(cytosol);GO:0008203(cholesterol metabolic process);GO:0006695(cholesterol biosynthetic process);GO:0045540(regulation of cholesterol biosynthetic process);GO:0019216(regulation of lipid metabolic process)","00650(Butanoate metabolism);00072(Synthesis and degradation of ketone bodies);00280(Valine, leucine and isoleucine degradation);00900(Terpenoid backbone biosynthesis)","K01641","EC:2.3.3.10","3-hydroxy-3-methylglutaryl-CoA synthase 1 [Source:HGNC Symbol;Acc:HGNC:5007]",{"v":3.544397,"d":"3.54"},{"v":0.598331,"d":"0.60"},{"v":5.92380638810291,"d":"5.92"},{"v":2.56652448878875,"d":"2.57"},{"v":0.000675877677878027,"d":"0.00"},{"v":0.0158740016401199,"d":"0.02"},"up","yes"]
[158925,0,"chr5","+",139274104,139329757,"ENST00000504203",17,2243,"MSTRG.12384","MATR3","GO:0005634(nucleus);GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0008270(zinc ion binding)","NA","NA","NA","matrin 3 [Source:NCBI gene;Acc:9782]",{"v":1.516582,"d":"1.52"},{"v":6.766018,"d":"6.77"},{"v":0.224146905905364,"d":"0.22"},{"v":-2.15748351013537,"d":"-2.16"},{"v":0.000676257498616388,"d":"0.00"},{"v":0.0158740016401199,"d":"0.02"},"down","yes"]
[104950,0,"chr19","+",52527653,52556336,"ENST00000359798",5,3600,"ENSG00000198482","ZNF808","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0005622(intracellular);GO:0003700(transcription factor activity, sequence-specific DNA binding)","NA","NA","NA","zinc finger protein 808 [Source:HGNC Symbol;Acc:HGNC:33230]",{"v":2.363751,"d":"2.36"},{"v":0.391077,"d":"0.39"},{"v":6.04420868524613,"d":"6.04"},{"v":2.59555347254315,"d":"2.60"},{"v":0.000678436456876366,"d":"0.00"},{"v":0.0158978247309089,"d":"0.02"},"up","yes"]
[120998,0,"chr2","-",241106295,241109780,"ENST00000472072",4,2024,"MSTRG.9521","PASK","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0005829(cytosol);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0005515(protein binding);GO:0045727(positive regulation of translation);GO:0008289(lipid binding);GO:0035091(phosphatidylinositol binding);GO:0046777(protein autophosphorylation);GO:2000505(regulation of energy homeostasis);GO:0070092(regulation of glucagon secretion);GO:0045719(negative regulation of glycogen biosynthetic process);GO:0043576(regulation of respiratory gaseous exchange)","NA","NA","NA","PAS domain containing serine/threonine kinase [Source:HGNC Symbol;Acc:HGNC:17270]",{"v":0.572717,"d":"0.57"},{"v":2.643417,"d":"2.64"},{"v":0.216657833402751,"d":"0.22"},{"v":-2.20650969577124,"d":"-2.21"},{"v":0.000678879214555188,"d":"0.00"},{"v":0.0158978247309089,"d":"0.02"},"down","yes"]
[172280,0,"chr7","-",22510616,22511999,"ENST00000434005",1,1384,"MSTRG.13517","EEF1A1P6","NA","NA","NA","NA","eukaryotic translation elongation factor 1 alpha 1 pseudogene 6 [Source:HGNC Symbol;Acc:HGNC:3201]",{"v":2.852019,"d":"2.85"},{"v":12.693496,"d":"12.69"},{"v":0.224683491451055,"d":"0.22"},{"v":-2.15403396804039,"d":"-2.15"},{"v":0.000683245099021914,"d":"0.00"},{"v":0.0159811513232218,"d":"0.02"},"down","yes"]
[193263,0,"chr9","-",124353466,124415439,"ENST00000259457",8,980,"MSTRG.14955","PSMB7","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0016787(hydrolase activity);GO:0005515(protein binding);GO:0008233(peptidase activity);GO:0006508(proteolysis);GO:0000502(proteasome complex);GO:0004175(endopeptidase activity);GO:0004298(threonine-type endopeptidase activity);GO:0051603(proteolysis involved in cellular protein catabolic process);GO:0005839(proteasome core complex);GO:0038095(Fc-epsilon receptor signaling pathway);GO:0005576(extracellular region);GO:0070062(extracellular exosome);GO:0000165(MAPK cascade);GO:0000209(protein polyubiquitination);GO:0002223(stimulatory C-type lectin receptor signaling pathway);GO:0002479(antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent);GO:0006521(regulation of cellular amino acid metabolic process);GO:0010972(negative regulation of G2/M transition of mitotic cell cycle);GO:0016579(protein deubiquitination);GO:0031145(anaphase-promoting complex-dependent catabolic process);GO:0031146(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process);GO:0033209(tumor necrosis factor-mediated signaling pathway);GO:0038061(NIK/NF-kappaB signaling);GO:0043161(proteasome-mediated ubiquitin-dependent protein catabolic process);GO:0043488(regulation of mRNA stability);GO:0043687(post-translational protein modification);GO:0050852(T cell receptor signaling pathway);GO:0051437(positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition);GO:0055085(transmembrane transport);GO:0060071(Wnt signaling pathway, planar cell polarity pathway);GO:0061418(regulation of transcription from RNA polymerase II promoter in response to hypoxia);GO:0090090(negative regulation of canonical Wnt signaling pathway);GO:0090263(positive regulation of canonical Wnt signaling pathway);GO:1902036(regulation of hematopoietic stem cell differentiation);GO:0019774(proteasome core complex, beta-subunit complex);GO:0016032(viral process);GO:0043312(neutrophil degranulation);GO:0051436(negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle);GO:0034774(secretory granule lumen);GO:1904813(ficolin-1-rich granule lumen);GO:1903955(positive regulation of protein targeting to mitochondrion)","03050(Proteasome)","K02739","EC:3.4.25.1","proteasome subunit beta 7 [Source:HGNC Symbol;Acc:HGNC:9544]",{"v":4.360828,"d":"4.36"},{"v":19.332653,"d":"19.33"},{"v":0.225568006625888,"d":"0.23"},{"v":-2.14836563688172,"d":"-2.15"},{"v":0.000684725325657014,"d":"0.00"},{"v":0.015996865105196,"d":"0.02"},"down","yes"]
[56208,0,"chr14","-",68787662,68793240,"ENST00000439696",2,3190,"MSTRG.4494","ZFP36L1","GO:0003723(RNA binding);GO:0006397(mRNA processing);GO:0006810(transport);GO:0051028(mRNA transport);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0003677(DNA binding);GO:0030529(intracellular ribonucleoprotein complex);GO:0005515(protein binding);GO:0007275(multicellular organism development);GO:0006355(regulation of transcription, DNA-templated);GO:0003729(mRNA binding);GO:0017091(AU-rich element binding);GO:0035925(mRNA 3'-UTR AU-rich region binding);GO:0000165(MAPK cascade);GO:0000288(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay);GO:0001570(vasculogenesis);GO:0003342(proepicardium development);GO:0006402(mRNA catabolic process);GO:0006417(regulation of translation);GO:0006915(apoptotic process);GO:0007507(heart development);GO:0008283(cell proliferation);GO:0021915(neural tube development);GO:0031086(nuclear-transcribed mRNA catabolic process, deadenylation-independent decay);GO:0033077(T cell differentiation in thymus);GO:0035264(multicellular organism growth);GO:0038066(p38MAPK cascade);GO:0043488(regulation of mRNA stability);GO:0043491(protein kinase B signaling);GO:0044344(cellular response to fibroblast growth factor stimulus);GO:0045577(regulation of B cell differentiation);GO:0045600(positive regulation of fat cell differentiation);GO:0045661(regulation of myoblast differentiation);GO:0048382(mesendoderm development);GO:0048568(embryonic organ development);GO:0060710(chorio-allantoic fusion);GO:0060712(spongiotrophoblast layer development);GO:0061158(3'-UTR-mediated mRNA destabilization);GO:0071320(cellular response to cAMP);GO:0071375(cellular response to peptide hormone stimulus);GO:0071472(cellular response to salt stress);GO:0072091(regulation of stem cell proliferation);GO:0097403(cellular response to raffinose);GO:1900153(positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay);GO:1901991(negative regulation of mitotic cell cycle phase transition);GO:0005829(cytosol);GO:0000932(P-body);GO:0071356(cellular response to tumor necrosis factor);GO:0070371(ERK1 and ERK2 cascade);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0014065(phosphatidylinositol 3-kinase signaling);GO:0071560(cellular response to transforming growth factor beta stimulus);GO:0032869(cellular response to insulin stimulus);GO:0071889(14-3-3 protein binding);GO:0071456(cellular response to hypoxia);GO:0031440(regulation of mRNA 3'-end processing);GO:0009611(response to wounding);GO:0071364(cellular response to epidermal growth factor stimulus);GO:0045616(regulation of keratinocyte differentiation);GO:0010468(regulation of gene expression);GO:0045647(negative regulation of erythrocyte differentiation);GO:0071385(cellular response to glucocorticoid stimulus);GO:1904628(cellular response to phorbol 13-acetate 12-myristate);GO:0010837(regulation of keratinocyte proliferation);GO:0045657(positive regulation of monocyte differentiation);GO:1902172(regulation of keratinocyte apoptotic process);GO:1904582(positive regulation of intracellular mRNA localization)","04218(Cellular senescence)","K18753","NA","ZFP36 ring finger protein like 1 [Source:HGNC Symbol;Acc:HGNC:1107]",{"v":110.002083,"d":"110.00"},{"v":19.07403,"d":"19.07"},{"v":5.7671128230374,"d":"5.77"},{"v":2.52784924636666,"d":"2.53"},{"v":0.000688872731035885,"d":"0.00"},{"v":0.0160747801907289,"d":"0.02"},"up","yes"]
[3478,0,"chr1","+",28887091,29120046,"ENST00000356093",19,5857,"MSTRG.337","EPB41","GO:0006810(transport);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0003779(actin binding);GO:0051301(cell division);GO:0005886(plasma membrane);GO:0005198(structural molecule activity);GO:0030054(cell junction);GO:0005856(cytoskeleton);GO:0008092(cytoskeletal protein binding);GO:0007049(cell cycle);GO:0005516(calmodulin binding);GO:0030866(cortical actin cytoskeleton organization);GO:0005515(protein binding);GO:0031032(actomyosin structure organization);GO:0005938(cell cortex);GO:0043234(protein complex);GO:0005200(structural constituent of cytoskeleton);GO:0030036(actin cytoskeleton organization);GO:0032092(positive regulation of protein binding);GO:0099738(cell cortex region);GO:1904778(positive regulation of protein localization to cell cortex);GO:0005545(1-phosphatidylinositol binding);GO:0047485(protein N-terminus binding);GO:0014731(spectrin-associated cytoskeleton);GO:0030863(cortical cytoskeleton);GO:0008022(protein C-terminus binding);GO:0030507(spectrin binding);GO:0051219(phosphoprotein binding);GO:0008360(regulation of cell shape);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0006461(protein complex assembly);GO:0009898(cytoplasmic side of plasma membrane);GO:0014069(postsynaptic density)","NA","NA","NA","erythrocyte membrane protein band 4.1 [Source:HGNC Symbol;Acc:HGNC:3377]",{"v":1.328956,"d":"1.33"},{"v":0.220959,"d":"0.22"},{"v":6.01449137622817,"d":"6.01"},{"v":2.58844273906064,"d":"2.59"},{"v":7.01624557736781E-4,"d":"0.00"},{"v":0.0163530585965788,"d":"0.02"},"up","yes"]
[134174,0,"chr3","-",25597905,25664372,"ENST00000264331",36,5358,"MSTRG.10746","TOP2B","GO:0005524(ATP binding);GO:0003677(DNA binding);GO:0006265(DNA topological change);GO:0003918(DNA topoisomerase type II (ATP-hydrolyzing) activity);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0016853(isomerase activity);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0006259(DNA metabolic process);GO:0003916(DNA topoisomerase activity);GO:0000712(resolution of meiotic recombination intermediates);GO:0003682(chromatin binding);GO:0008022(protein C-terminus binding);GO:0019899(enzyme binding);GO:0046982(protein heterodimerization activity);GO:0042826(histone deacetylase binding);GO:0016925(protein sumoylation);GO:0000792(heterochromatin);GO:0005080(protein kinase C binding);GO:0000819(sister chromatid segregation);GO:0044774(mitotic DNA integrity checkpoint);GO:0001764(neuron migration);GO:0007409(axonogenesis);GO:0030900(forebrain development)","01524(Platinum drug resistance)","K03164","EC:5.99.1.3","topoisomerase (DNA) II beta [Source:HGNC Symbol;Acc:HGNC:11990]",{"v":3.258271,"d":"3.26"},{"v":0.556109,"d":"0.56"},{"v":5.85905101338047,"d":"5.86"},{"v":2.55066701120728,"d":"2.55"},{"v":0.000707045601672409,"d":"0.00"},{"v":0.0164600216069337,"d":"0.02"},"up","yes"]
[89104,0,"chr17","+",80260868,80398786,"ENST00000582970",68,21055,"MSTRG.7310","RNF213","GO:0046872(metal ion binding);GO:0005730(nucleolus);GO:0005829(cytosol);GO:0016567(protein ubiquitination);GO:0004842(ubiquitin-protein transferase activity);GO:0016887(ATPase activity);GO:0001525(angiogenesis);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0016740(transferase activity);GO:0016787(hydrolase activity);GO:0006511(ubiquitin-dependent protein catabolic process);GO:0002040(sprouting angiogenesis);GO:0000209(protein polyubiquitination);GO:0051260(protein homooligomerization);GO:0051865(protein autoubiquitination);GO:2000051(negative regulation of non-canonical Wnt signaling pathway)","NA","NA","NA","ring finger protein 213 [Source:HGNC Symbol;Acc:HGNC:14539]",{"v":22.261826,"d":"22.26"},{"v":3.876651,"d":"3.88"},{"v":5.74254066203019,"d":"5.74"},{"v":2.52168916713679,"d":"2.52"},{"v":0.000708768595965081,"d":"0.00"},{"v":0.0164807438037098,"d":"0.02"},"up","yes"]
[100373,0,"chr19","-",35904461,35908223,"ENST00000588439",4,594,"MSTRG.8084","TYROBP","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005515(protein binding);GO:0050776(regulation of immune response);GO:0005886(plasma membrane);GO:0042802(identical protein binding);GO:0045087(innate immune response);GO:0005887(integral component of plasma membrane);GO:0005102(receptor binding);GO:0043312(neutrophil degranulation);GO:0007165(signal transduction);GO:0009986(cell surface);GO:0030667(secretory granule membrane);GO:0035556(intracellular signal transduction);GO:0005057(signal transducer activity, downstream of receptor);GO:0006968(cellular defense response);GO:0002281(macrophage activation involved in immune response);GO:0002283(neutrophil activation involved in immune response);GO:0007229(integrin-mediated signaling pathway);GO:2001204(regulation of osteoclast development)","04650(Natural killer cell mediated cytotoxicity);04380(Osteoclast differentiation)","NA","NA","TYRO protein tyrosine kinase binding protein [Source:HGNC Symbol;Acc:HGNC:12449]",{"v":5.089529,"d":"5.09"},{"v":22.620611,"d":"22.62"},{"v":0.224995204594606,"d":"0.22"},{"v":-2.15203384180641,"d":"-2.15"},{"v":0.000711884828735677,"d":"0.00"},{"v":0.0165272086170747,"d":"0.02"},"down","yes"]
[167098,0,"chr6","+",70566917,70589569,"ENST00000370474",3,1196,"ENSG00000154079","SDHAF4","GO:0008177(succinate dehydrogenase (ubiquinone) activity);GO:0005739(mitochondrion);GO:0005759(mitochondrial matrix);GO:0003674(molecular_function);GO:0005575(cellular_component);GO:0034553(mitochondrial respiratory chain complex II assembly);GO:0005749(mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone));GO:0045333(cellular respiration);GO:0003407(neural retina development);GO:0045087(innate immune response);GO:0097032(mitochondrial respiratory chain complex II biogenesis)","NA","NA","NA","succinate dehydrogenase complex assembly factor 4 [Source:HGNC Symbol;Acc:HGNC:20957]",{"v":0.647919,"d":"0.65"},{"v":3.03952,"d":"3.04"},{"v":0.213164907616992,"d":"0.21"},{"v":-2.22995814165898,"d":"-2.23"},{"v":0.000713174346422581,"d":"0.00"},{"v":0.0165272086170747,"d":"0.02"},"down","yes"]
[63139,0,"chr15","-",59639109,59657479,"ENST00000396061",5,758,"MSTRG.5144","GTF2A2","GO:0051091(positive regulation of sequence-specific DNA binding transcription factor activity);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0030054(cell junction);GO:0005515(protein binding);GO:0001103(RNA polymerase II repressing transcription factor binding);GO:0008134(transcription factor binding);GO:0006367(transcription initiation from RNA polymerase II promoter);GO:0005672(transcription factor TFIIA complex);GO:0016032(viral process);GO:0042803(protein homodimerization activity);GO:0046982(protein heterodimerization activity);GO:0003713(transcription coactivator activity);GO:0006366(transcription from RNA polymerase II promoter);GO:0006368(transcription elongation from RNA polymerase II promoter);GO:0042795(snRNA transcription from RNA polymerase II promoter);GO:0005669(transcription factor TFIID complex);GO:0017025(TBP-class protein binding);GO:0051123(RNA polymerase II transcriptional preinitiation complex assembly)","03022(Basal transcription factors);05203(Viral carcinogenesis)","K03123","NA","general transcription factor IIA subunit 2 [Source:HGNC Symbol;Acc:HGNC:4647]",{"v":0.975455,"d":"0.98"},{"v":4.62099,"d":"4.62"},{"v":0.211092211842051,"d":"0.21"},{"v":-2.24405474284427,"d":"-2.24"},{"v":0.000713272496411046,"d":"0.00"},{"v":0.0165272086170747,"d":"0.02"},"down","yes"]
[177238,0,"chr7","+",102363897,102426676,"ENST00000496391",10,3430,"ENSG00000128563","PRKRIP1","GO:0005634(nucleus);GO:0003725(double-stranded RNA binding);GO:0004860(protein kinase inhibitor activity);GO:0019901(protein kinase binding);GO:0006469(negative regulation of protein kinase activity);GO:0042326(negative regulation of phosphorylation);GO:0005730(nucleolus);GO:0005515(protein binding);GO:0070062(extracellular exosome);GO:0003014(renal system process)","NA","NA","NA","PRKR interacting protein 1 (IL11 inducible) [Source:HGNC Symbol;Acc:HGNC:21894]",{"v":0.430561,"d":"0.43"},{"v":1.949492,"d":"1.95"},{"v":0.220858049173836,"d":"0.22"},{"v":-2.17880868251579,"d":"-2.18"},{"v":0.000719331546018357,"d":"0.00"},{"v":0.0166481083422354,"d":"0.02"},"down","yes"]
[105078,0,"chr19","-",53066614,53103434,"ENST00000418871",6,4219,"ENSG00000170949","ZNF160","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0005622(intracellular);GO:0030097(hemopoiesis)","NA","NA","NA","zinc finger protein 160 [Source:HGNC Symbol;Acc:HGNC:12948]",{"v":0.284238,"d":"0.28"},{"v":1.30155,"d":"1.30"},{"v":0.218384234182321,"d":"0.22"},{"v":-2.19505938738411,"d":"-2.20"},{"v":0.00072227910441514,"d":"0.00"},{"v":0.0166967978015967,"d":"0.02"},"down","yes"]
[33853,0,"chr11","-",85957688,86069097,"ENST00000526033",20,3613,"MSTRG.2788","PICALM","GO:0048471(perinuclear region of cytoplasm);GO:0005634(nucleus);GO:0016020(membrane);GO:0043231(intracellular membrane-bounded organelle);GO:0006897(endocytosis);GO:0005794(Golgi apparatus);GO:0031410(cytoplasmic vesicle);GO:0005543(phospholipid binding);GO:0005545(1-phosphatidylinositol binding);GO:0030276(clathrin binding);GO:0048268(clathrin coat assembly);GO:0030136(clathrin-coated vesicle);GO:0005905(clathrin-coated pit);GO:0005515(protein binding);GO:0005829(cytosol);GO:0045296(cadherin binding);GO:0061024(membrane organization);GO:0016192(vesicle-mediated transport);GO:0045893(positive regulation of transcription, DNA-templated);GO:0006461(protein complex assembly);GO:0042734(presynaptic membrane);GO:0030132(clathrin coat of coated pit);GO:0006898(receptor-mediated endocytosis);GO:0030122(AP-2 adaptor complex);GO:0016197(endosomal transport);GO:0050750(low-density lipoprotein particle receptor binding);GO:0032050(clathrin heavy chain binding);GO:0032880(regulation of protein localization);GO:0048261(negative regulation of receptor-mediated endocytosis);GO:0045211(postsynaptic membrane);GO:1901216(positive regulation of neuron death);GO:1902004(positive regulation of amyloid-beta formation);GO:0097418(neurofibrillary tangle);GO:0045056(transcytosis);GO:0031623(receptor internalization);GO:0030100(regulation of endocytosis);GO:0072583(clathrin-dependent endocytosis);GO:0005769(early endosome);GO:0017137(Rab GTPase binding);GO:0035615(clathrin adaptor activity);GO:0008283(cell proliferation);GO:0010629(negative regulation of gene expression);GO:0016188(synaptic vesicle maturation);GO:0035459(cargo loading into vesicle);GO:0043547(positive regulation of GTPase activity);GO:0055072(iron ion homeostasis);GO:0098711(iron ion import across plasma membrane);GO:1902959(regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process);GO:1902961(positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process);GO:1902963(negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process);GO:0009986(cell surface);GO:0031982(vesicle);GO:0043025(neuronal cell body);GO:0070381(endosome to plasma membrane transport vesicle);GO:0007409(axonogenesis);GO:0007611(learning or memory);GO:0030097(hemopoiesis);GO:0048813(dendrite morphogenesis);GO:0090647(modulation of age-related behavioral decline);GO:1900223(positive regulation of amyloid-beta clearance);GO:0005622(intracellular)","NA","NA","NA","phosphatidylinositol binding clathrin assembly protein [Source:HGNC Symbol;Acc:HGNC:15514]",{"v":1.38211,"d":"1.38"},{"v":0.226945,"d":"0.23"},{"v":6.09006587499174,"d":"6.09"},{"v":2.60645783355195,"d":"2.61"},{"v":0.000726256256899677,"d":"0.00"},{"v":0.0167691468045867,"d":"0.02"},"up","yes"]
[143861,0,"chr3","+",186783577,186789881,"ENST00000425053",12,1977,"MSTRG.11403","EIF4A2","GO:0003676(nucleic acid binding);GO:0005524(ATP binding);GO:0003723(RNA binding);GO:0003743(translation initiation factor activity);GO:0006412(translation);GO:0006413(translational initiation);GO:0000166(nucleotide binding);GO:0016787(hydrolase activity);GO:0004386(helicase activity);GO:0005515(protein binding);GO:0048471(perinuclear region of cytoplasm);GO:0005730(nucleolus);GO:0005829(cytosol);GO:0004004(ATP-dependent RNA helicase activity);GO:0010501(RNA secondary structure unwinding);GO:0000289(nuclear-transcribed mRNA poly(A) tail shortening);GO:0016032(viral process);GO:0016887(ATPase activity);GO:0006446(regulation of translational initiation);GO:0016281(eukaryotic translation initiation factor 4F complex);GO:1900260(negative regulation of RNA-directed 5'-3' RNA polymerase activity);GO:1990830(cellular response to leukemia inhibitory factor)","03013(RNA transport)","NA","NA","eukaryotic translation initiation factor 4A2 [Source:HGNC Symbol;Acc:HGNC:3284]",{"v":1.024309,"d":"1.02"},{"v":4.594911,"d":"4.59"},{"v":0.222922489684784,"d":"0.22"},{"v":-2.16538592369123,"d":"-2.17"},{"v":0.000728849362855331,"d":"0.00"},{"v":0.0168091898187392,"d":"0.02"},"down","yes"]
[190151,0,"chr9","+",36136742,36162910,"ENST00000377959",4,812,"MSTRG.14756","GLIPR2","GO:0005576(extracellular region);GO:0016020(membrane);GO:0005794(Golgi apparatus);GO:0042803(protein homodimerization activity);GO:0000139(Golgi membrane);GO:0070062(extracellular exosome);GO:0070374(positive regulation of ERK1 and ERK2 cascade);GO:0010718(positive regulation of epithelial to mesenchymal transition);GO:0010634(positive regulation of epithelial cell migration)","NA","NA","NA","GLI pathogenesis related 2 [Source:HGNC Symbol;Acc:HGNC:18007]",{"v":0.956794,"d":"0.96"},{"v":4.452664,"d":"4.45"},{"v":0.214881248618804,"d":"0.21"},{"v":-2.21838850186099,"d":"-2.22"},{"v":0.000729689410465788,"d":"0.00"},{"v":0.0168091898187392,"d":"0.02"},"down","yes"]
[170567,0,"chr6","-",159682165,159693278,"ENST00000337404",4,991,"MSTRG.13403","SOD2","GO:0046872(metal ion binding);GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0004784(superoxide dismutase activity);GO:0006801(superoxide metabolic process);GO:0003677(DNA binding);GO:0019825(oxygen binding);GO:0019899(enzyme binding);GO:0030145(manganese ion binding);GO:0042802(identical protein binding);GO:0000302(response to reactive oxygen species);GO:0000303(response to superoxide);GO:0001306(age-dependent response to oxidative stress);GO:0001666(response to hypoxia);GO:0001836(release of cytochrome c from mitochondria);GO:0001889(liver development);GO:0003032(detection of oxygen);GO:0003069(acetylcholine-mediated vasodilation involved in regulation of systemic arterial blood pressure);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0006749(glutathione metabolic process);GO:0006979(response to oxidative stress);GO:0007005(mitochondrion organization);GO:0007507(heart development);GO:0007568(aging);GO:0007626(locomotory behavior);GO:0008217(regulation of blood pressure);GO:0008630(intrinsic apoptotic signaling pathway in response to DNA damage);GO:0008631(intrinsic apoptotic signaling pathway in response to oxidative stress);GO:0008637(apoptotic mitochondrial changes);GO:0009314(response to radiation);GO:0009409(response to cold);GO:0009791(post-embryonic development);GO:0010042(response to manganese ion);GO:0010043(response to zinc ion);GO:0010269(response to selenium ion);GO:0010332(response to gamma radiation);GO:0014823(response to activity);GO:0019430(removal of superoxide radicals);GO:0022904(respiratory electron transport chain);GO:0030097(hemopoiesis);GO:0031667(response to nutrient levels);GO:0032496(response to lipopolysaccharide);GO:0033591(response to L-ascorbic acid);GO:0034021(response to silicon dioxide);GO:0035900(response to isolation stress);GO:0035902(response to immobilization stress);GO:0042311(vasodilation);GO:0042493(response to drug);GO:0042542(response to hydrogen peroxide);GO:0042554(superoxide anion generation);GO:0042743(hydrogen peroxide metabolic process);GO:0043066(negative regulation of apoptotic process);GO:0045429(positive regulation of nitric oxide biosynthetic process);GO:0045599(negative regulation of fat cell differentiation);GO:0046686(response to cadmium ion);GO:0048147(negative regulation of fibroblast proliferation);GO:0048666(neuron development);GO:0048678(response to axon injury);GO:0048773(erythrophore differentiation);GO:0050665(hydrogen peroxide biosynthetic process);GO:0050790(regulation of catalytic activity);GO:0051260(protein homooligomerization);GO:0051602(response to electrical stimulus);GO:0051881(regulation of mitochondrial membrane potential);GO:0055072(iron ion homeostasis);GO:0055093(response to hyperoxia);GO:0071000(response to magnetism);GO:0071361(cellular response to ethanol);GO:0005737(cytoplasm);GO:0005739(mitochondrion);GO:0005743(mitochondrial inner membrane);GO:0042645(mitochondrial nucleoid);GO:0043209(myelin sheath);GO:0008285(negative regulation of cell proliferation);GO:0030335(positive regulation of cell migration);GO:0005759(mitochondrial matrix);GO:0070062(extracellular exosome);GO:0035722(interleukin-12-mediated signaling pathway);GO:0051289(protein homotetramerization);GO:0034599(cellular response to oxidative stress);GO:0043524(negative regulation of neuron apoptotic process);GO:1902176(negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway);GO:0001315(age-dependent response to reactive oxygen species);GO:0032364(oxygen homeostasis)","04068(FoxO signaling pathway);04146(Peroxisome);04211(Longevity regulating pathway - mammal);04213(Longevity regulating pathway - multiple species);05016(Huntington's disease)","K04564","EC:1.15.1.1","superoxide dismutase 2 [Source:HGNC Symbol;Acc:HGNC:11180]",{"v":101.154358,"d":"101.15"},{"v":17.661531,"d":"17.66"},{"v":5.72738331688232,"d":"5.73"},{"v":2.51787616202057,"d":"2.52"},{"v":0.000732065155774365,"d":"0.00"},{"v":0.0168159934724469,"d":"0.02"},"up","yes"]
[83521,0,"chr17","-",42313324,42388568,"ENST00000264657",24,5047,"MSTRG.6829","STAT3","GO:0035278(miRNA mediated inhibition of translation);GO:0010628(positive regulation of gene expression);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0005737(cytoplasm);GO:1904685(positive regulation of metalloendopeptidase activity);GO:0005634(nucleus);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0016310(phosphorylation);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0007165(signal transduction);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0004871(signal transducer activity);GO:0031490(chromatin DNA binding);GO:0042803(protein homodimerization activity);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0045893(positive regulation of transcription, DNA-templated);GO:0006954(inflammatory response);GO:0042802(identical protein binding);GO:0019901(protein kinase binding);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0016032(viral process);GO:0007399(nervous system development);GO:0035722(interleukin-12-mediated signaling pathway);GO:0019903(protein phosphatase binding);GO:0008134(transcription factor binding);GO:0060259(regulation of feeding behavior);GO:0000790(nuclear chromatin);GO:0051726(regulation of cell cycle);GO:0006928(movement of cell or subcellular component);GO:0044212(transcription regulatory region DNA binding);GO:0090575(RNA polymerase II transcription factor complex);GO:0045747(positive regulation of Notch signaling pathway);GO:0007259(JAK-STAT cascade);GO:0032355(response to estradiol);GO:0032870(cellular response to hormone stimulus);GO:0060396(growth hormone receptor signaling pathway);GO:0042531(positive regulation of tyrosine phosphorylation of STAT protein);GO:1902895(positive regulation of pri-miRNA transcription from RNA polymerase II promoter);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0001103(RNA polymerase II repressing transcription factor binding);GO:0019221(cytokine-mediated signaling pathway);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:0035019(somatic stem cell population maintenance);GO:0060019(radial glial cell differentiation);GO:0042593(glucose homeostasis);GO:0001077(transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0046983(protein dimerization activity);GO:0070102(interleukin-6-mediated signaling pathway);GO:0060397(JAK-STAT cascade involved in growth hormone signaling pathway);GO:0001659(temperature homeostasis);GO:0043066(negative regulation of apoptotic process);GO:0001228(transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding);GO:0072540(T-helper 17 cell lineage commitment);GO:0042755(eating behavior);GO:0019953(sexual reproduction);GO:0004879(RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding);GO:0030522(intracellular receptor signaling pathway);GO:0045648(positive regulation of erythrocyte differentiation);GO:0044321(response to leptin);GO:0033210(leptin-mediated signaling pathway);GO:0000981(RNA polymerase II transcription factor activity, sequence-specific DNA binding);GO:0031730(CCR5 chemokine receptor binding);GO:0035259(glucocorticoid receptor binding);GO:0043565(sequence-specific DNA binding);GO:0001754(eye photoreceptor cell differentiation);GO:0006366(transcription from RNA polymerase II promoter);GO:0006606(protein import into nucleus);GO:0006953(acute-phase response);GO:0007568(aging);GO:0008283(cell proliferation);GO:0008284(positive regulation of cell proliferation);GO:0008285(negative regulation of cell proliferation);GO:0010033(response to organic substance);GO:0010730(negative regulation of hydrogen peroxide biosynthetic process);GO:0014070(response to organic cyclic compound);GO:0019827(stem cell population maintenance);GO:0034097(response to cytokine);GO:0040014(regulation of multicellular organism growth);GO:0042493(response to drug);GO:0042789(mRNA transcription from RNA polymerase II promoter);GO:0043434(response to peptide hormone);GO:0044320(cellular response to leptin stimulus);GO:0045471(response to ethanol);GO:0045820(negative regulation of glycolytic process);GO:0046902(regulation of mitochondrial membrane permeability);GO:0048708(astrocyte differentiation);GO:0060548(negative regulation of cell death);GO:0071345(cellular response to cytokine stimulus);GO:0071407(cellular response to organic cyclic compound);GO:0097009(energy homeostasis);GO:1901215(negative regulation of neuron death);GO:1902728(positive regulation of growth factor dependent skeletal muscle satellite cell proliferation);GO:2000637(positive regulation of gene silencing by miRNA);GO:2000737(negative regulation of stem cell differentiation);GO:2001171(positive regulation of ATP biosynthetic process);GO:2001223(negative regulation of neuron migration);GO:0005739(mitochondrion);GO:0005743(mitochondrial inner membrane)","04630(Jak-STAT signaling pathway);04066(HIF-1 signaling pathway);04068(FoxO signaling pathway);04217(Necroptosis);04550(Signaling pathways regulating pluripotency of stem cells);04659(Th17 cell differentiation);04062(Chemokine signaling pathway);04920(Adipocytokine signaling pathway);04917(Prolactin signaling pathway);05200(Pathways in cancer);05206(MicroRNAs in cancer);05205(Proteoglycans in cancer);05203(Viral carcinogenesis);05212(Pancreatic cancer);05221(Acute myeloid leukemia);05223(Non-small cell lung cancer);05321(Inflammatiory bowel disease (IBD));04931(Insulin resistance);04933(AGE-RAGE signaling pathway in diabetic complications);05162(Measles);05161(Hepatitis B);05160(Hepatitis C);05167(Kaposi's sarcoma-associated herpesvirus infection);05169(Epstein-Barr virus infection);05145(Toxoplasmosis);01521(EGFR tyrosine kinase inhibitor resistance)","K04692","NA","signal transducer and activator of transcription 3 [Source:HGNC Symbol;Acc:HGNC:11364]",{"v":1.815558,"d":"1.82"},{"v":7.908646,"d":"7.91"},{"v":0.229566224104607,"d":"0.23"},{"v":-2.1230176998306,"d":"-2.12"},{"v":0.000732182579873137,"d":"0.00"},{"v":0.0168159934724469,"d":"0.02"},"down","yes"]
[63146,0,"chr15","-",59659146,59689534,"ENST00000267859",10,6325,"MSTRG.5146","BNIP2","GO:0001824(blastocyst development);GO:0007098(centrosome cycle);GO:0043410(positive regulation of MAPK cascade);GO:0045666(positive regulation of neuron differentiation);GO:0051057(positive regulation of small GTPase mediated signal transduction);GO:0051146(striated muscle cell differentiation);GO:0005814(centriole);GO:0031616(spindle pole centrosome);GO:0005737(cytoplasm);GO:0043547(positive regulation of GTPase activity);GO:0005515(protein binding);GO:0006915(apoptotic process);GO:0048471(perinuclear region of cytoplasm);GO:0005509(calcium ion binding);GO:0005829(cytosol);GO:0043231(intracellular membrane-bounded organelle);GO:0043066(negative regulation of apoptotic process);GO:0005635(nuclear envelope);GO:0005096(GTPase activator activity);GO:0051149(positive regulation of muscle cell differentiation);GO:0042802(identical protein binding);GO:0016020(membrane);GO:0016021(integral component of membrane)","NA","NA","NA","BCL2 interacting protein 2 [Source:HGNC Symbol;Acc:HGNC:1083]",{"v":0.434693,"d":"0.43"},{"v":1.926408,"d":"1.93"},{"v":0.225649498963875,"d":"0.23"},{"v":-2.14784451971891,"d":"-2.15"},{"v":0.000732534180980856,"d":"0.00"},{"v":0.0168159934724469,"d":"0.02"},"down","yes"]
[106536,0,"chr19","+",58278951,58302805,"ENST00000621650",4,9128,"MSTRG.8467","ZNF8","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0005622(intracellular);GO:0008270(zinc ion binding);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0030509(BMP signaling pathway)","NA","NA","NA","zinc finger protein 8 [Source:HGNC Symbol;Acc:HGNC:13154]",{"v":0.106783,"d":"0.11"},{"v":0.488329,"d":"0.49"},{"v":0.218670199803821,"d":"0.22"},{"v":-2.19317147040721,"d":"-2.19"},{"v":0.000739439063274504,"d":"0.00"},{"v":0.0169399043292477,"d":"0.02"},"down","yes"]
[199321,0,"chrX","+",109536876,109544690,"ENST00000372106",4,2562,"ENSG00000101888","NXT2","GO:0006810(transport);GO:0051028(mRNA transport);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0015031(protein transport);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0005622(intracellular);GO:0005515(protein binding);GO:0048471(perinuclear region of cytoplasm)","03013(RNA transport);03015(mRNA surveillance pathway);03008(Ribosome biogenesis in eukaryotes);05164(Influenza A)","K14285","NA","nuclear transport factor 2 like export factor 2 [Source:HGNC Symbol;Acc:HGNC:18151]",{"v":2.746165,"d":"2.75"},{"v":0.456323,"d":"0.46"},{"v":6.01802889619853,"d":"6.02"},{"v":2.58929103393982,"d":"2.59"},{"v":0.000740416808662197,"d":"0.00"},{"v":0.0169399043292477,"d":"0.02"},"up","yes"]
[49805,0,"chr13","-",39009866,39038076,"ENST00000625998",12,5102,"MSTRG.3950","PROSER1","NA","NA","NA","NA","proline and serine rich 1 [Source:HGNC Symbol;Acc:HGNC:20291]",{"v":0.419852,"d":"0.42"},{"v":1.868559,"d":"1.87"},{"v":0.224692931826076,"d":"0.22"},{"v":-2.15397335256738,"d":"-2.15"},{"v":0.00074050016397813,"d":"0.00"},{"v":0.0169399043292477,"d":"0.02"},"down","yes"]
[194812,0,"chr9","-",136494444,136545862,"ENST00000277541",34,9371,"MSTRG.15095","NOTCH1","GO:0008284(positive regulation of cell proliferation);GO:0010812(negative regulation of cell-substrate adhesion);GO:0060045(positive regulation of cardiac muscle cell proliferation);GO:0010718(positive regulation of epithelial to mesenchymal transition);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0060412(ventricular septum morphogenesis);GO:0030335(positive regulation of cell migration);GO:0005634(nucleus);GO:0030514(negative regulation of BMP signaling pathway);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0046872(metal ion binding);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0005509(calcium ion binding);GO:0007275(multicellular organism development);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0030154(cell differentiation);GO:0006955(immune response);GO:0007219(Notch signaling pathway);GO:0004872(receptor activity);GO:0045893(positive regulation of transcription, DNA-templated);GO:0005576(extracellular region);GO:0050793(regulation of developmental process);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0060271(cilium assembly);GO:0005789(endoplasmic reticulum membrane);GO:0001047(core promoter binding);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0008285(negative regulation of cell proliferation);GO:0005912(adherens junction);GO:0016324(apical plasma membrane);GO:0019899(enzyme binding);GO:0006367(transcription initiation from RNA polymerase II promoter);GO:0045892(negative regulation of transcription, DNA-templated);GO:0000139(Golgi membrane);GO:0001525(angiogenesis);GO:0001947(heart looping);GO:0007368(determination of left/right symmetry);GO:0045662(negative regulation of myoblast differentiation);GO:0097150(neuronal stem cell population maintenance);GO:0035148(tube formation);GO:0035924(cellular response to vascular endothelial growth factor stimulus);GO:0090051(negative regulation of cell migration involved in sprouting angiogenesis);GO:0004857(enzyme inhibitor activity);GO:0043086(negative regulation of catalytic activity);GO:0043235(receptor complex);GO:0055008(cardiac muscle tissue morphogenesis);GO:0001190(transcriptional activator activity, RNA polymerase II transcription factor binding);GO:0003184(pulmonary valve morphogenesis);GO:0030279(negative regulation of ossification);GO:0001837(epithelial to mesenchymal transition);GO:0003198(epithelial to mesenchymal transition involved in endocardial cushion formation);GO:0003273(cell migration involved in endocardial cushion formation);GO:2000811(negative regulation of anoikis);GO:0045668(negative regulation of osteoblast differentiation);GO:2000737(negative regulation of stem cell differentiation);GO:0061314(Notch signaling involved in heart development);GO:0060411(cardiac septum morphogenesis);GO:1901201(regulation of extracellular matrix assembly);GO:2001027(negative regulation of endothelial cell chemotaxis);GO:0010832(negative regulation of myotube differentiation);GO:0046427(positive regulation of JAK-STAT cascade);GO:0003203(endocardial cushion morphogenesis);GO:0048711(positive regulation of astrocyte differentiation);GO:0060317(cardiac epithelial to mesenchymal transition);GO:0003180(aortic valve morphogenesis);GO:0030513(positive regulation of BMP signaling pathway);GO:0003169(coronary vein morphogenesis);GO:0060948(cardiac vascular smooth muscle cell development);GO:0060982(coronary artery morphogenesis);GO:0003214(cardiac left ventricle morphogenesis);GO:0003208(cardiac ventricle morphogenesis);GO:0003209(cardiac atrium morphogenesis);GO:0003222(ventricular trabecula myocardium morphogenesis);GO:0003344(pericardium morphogenesis);GO:0061384(heart trabecula morphogenesis);GO:0050768(negative regulation of neurogenesis);GO:0060956(endocardial cell differentiation);GO:0060253(negative regulation of glial cell proliferation);GO:0003181(atrioventricular valve morphogenesis);GO:0003682(chromatin binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0005112(Notch binding);GO:0031490(chromatin DNA binding);GO:0043565(sequence-specific DNA binding);GO:0046982(protein heterodimerization activity);GO:0001701(in utero embryonic development);GO:0001708(cell fate specification);GO:0001889(liver development);GO:0002040(sprouting angiogenesis);GO:0002052(positive regulation of neuroblast proliferation);GO:0002437(inflammatory response to antigenic stimulus);GO:0003157(endocardium development);GO:0003160(endocardium morphogenesis);GO:0003162(atrioventricular node development);GO:0003192(mitral valve formation);GO:0003197(endocardial cushion development);GO:0003207(cardiac chamber formation);GO:0003213(cardiac right atrium morphogenesis);GO:0003219(cardiac right ventricle formation);GO:0003241(growth involved in heart morphogenesis);GO:0003256(regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation);GO:0003264(regulation of cardioblast proliferation);GO:0003270(Notch signaling pathway involved in regulation of secondary heart field cardioblast proliferation);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0006959(humoral immune response);GO:0007221(positive regulation of transcription of Notch receptor target);GO:0007283(spermatogenesis);GO:0007386(compartment pattern specification);GO:0007409(axonogenesis);GO:0007420(brain development);GO:0007440(foregut morphogenesis);GO:0007492(endoderm development);GO:0007507(heart development);GO:0008544(epidermis development);GO:0008593(regulation of Notch signaling pathway);GO:0009912(auditory receptor cell fate commitment);GO:0010001(glial cell differentiation);GO:0010468(regulation of gene expression);GO:0014031(mesenchymal cell development);GO:0014807(regulation of somitogenesis);GO:0021515(cell differentiation in spinal cord);GO:0021915(neural tube development);GO:0030182(neuron differentiation);GO:0030216(keratinocyte differentiation);GO:0030324(lung development);GO:0030326(embryonic limb morphogenesis);GO:0030334(regulation of cell migration);GO:0030900(forebrain development);GO:0031069(hair follicle morphogenesis);GO:0031100(animal organ regeneration);GO:0031960(response to corticosteroid);GO:0032495(response to muramyl dipeptide);GO:0032496(response to lipopolysaccharide);GO:0035116(embryonic hindlimb morphogenesis);GO:0035914(skeletal muscle cell differentiation);GO:0042127(regulation of cell proliferation);GO:0042246(tissue regeneration);GO:0043065(positive regulation of apoptotic process);GO:0045070(positive regulation of viral genome replication);GO:0045165(cell fate commitment);GO:0045596(negative regulation of cell differentiation);GO:0045603(positive regulation of endothelial cell differentiation);GO:0045607(regulation of auditory receptor cell differentiation);GO:0045608(negative regulation of auditory receptor cell differentiation);GO:0045618(positive regulation of keratinocyte differentiation);GO:0045665(negative regulation of neuron differentiation);GO:0045687(positive regulation of glial cell differentiation);GO:0045747(positive regulation of Notch signaling pathway);GO:0045955(negative regulation of calcium ion-dependent exocytosis);GO:0046533(negative regulation of photoreceptor cell differentiation);GO:0048103(somatic stem cell division);GO:0048663(neuron fate commitment);GO:0048708(astrocyte differentiation);GO:0048709(oligodendrocyte differentiation);GO:0048715(negative regulation of oligodendrocyte differentiation);GO:0048754(branching morphogenesis of an epithelial tube);GO:0048845(venous blood vessel morphogenesis);GO:0050678(regulation of epithelial cell proliferation);GO:0050679(positive regulation of epithelial cell proliferation);GO:0050767(regulation of neurogenesis);GO:0060038(cardiac muscle cell proliferation);GO:0060528(secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development);GO:0060548(negative regulation of cell death);GO:0060740(prostate gland epithelium morphogenesis);GO:0060768(regulation of epithelial cell proliferation involved in prostate gland development);GO:0060842(arterial endothelial cell differentiation);GO:0060843(venous endothelial cell differentiation);GO:0060979(vasculogenesis involved in coronary vascular morphogenesis);GO:0061419(positive regulation of transcription from RNA polymerase II promoter in response to hypoxia);GO:0070986(left/right axis specification);GO:0071372(cellular response to follicle-stimulating hormone stimulus);GO:0072017(distal tubule development);GO:0072044(collecting duct development);GO:0072144(glomerular mesangial cell development);GO:0072602(interleukin-4 secretion);GO:0090090(negative regulation of canonical Wnt signaling pathway);GO:1902263(apoptotic process involved in embryonic digit morphogenesis);GO:1903849(positive regulation of aorta morphogenesis);GO:2000974(negative regulation of pro-B cell differentiation);GO:0001669(acrosomal vesicle);GO:0002193(MAML1-RBP-Jkappa- ICN1 complex);GO:0005737(cytoplasm);GO:0005783(endoplasmic reticulum);GO:0005794(Golgi apparatus);GO:0009986(cell surface);GO:0031410(cytoplasmic vesicle);GO:0071944(cell periphery)","04330(Notch signaling pathway);04658(Th1 and Th2 cell differentiation);04919(Thyroid hormone signaling pathway);05200(Pathways in cancer);05206(MicroRNAs in cancer);05224(Breast cancer);05020(Prion diseases);05165(Human papillomavirus infection);01522(Endocrine resistance)","K02599","NA","notch 1 [Source:HGNC Symbol;Acc:HGNC:7881]",{"v":31.270353,"d":"31.27"},{"v":5.479231,"d":"5.48"},{"v":5.70706965995776,"d":"5.71"},{"v":2.51275017252238,"d":"2.51"},{"v":0.00074153747617486,"d":"0.00"},{"v":0.0169440457027115,"d":"0.02"},"up","yes"]
[197064,0,"chrX","+",48897931,48903136,"ENST00000447146",7,1020,"MSTRG.15287","PQBP1","GO:0006397(mRNA processing);GO:0008380(RNA splicing);GO:0005634(nucleus);GO:0016607(nuclear speck);GO:0005829(cytosol);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0005515(protein binding);GO:0005654(nucleoplasm);GO:0003677(DNA binding);GO:0003713(transcription coactivator activity);GO:0031175(neuron projection development);GO:0000398(mRNA splicing, via spliceosome);GO:0043021(ribonucleoprotein complex binding);GO:0000380(alternative mRNA splicing, via spliceosome);GO:0043484(regulation of RNA splicing);GO:0034063(stress granule assembly);GO:0048814(regulation of dendrite morphogenesis);GO:0005737(cytoplasm);GO:0010494(cytoplasmic stress granule);GO:0071598(neuronal ribonucleoprotein granule)","03040(Spliceosome)","K12865","NA","polyglutamine binding protein 1 [Source:HGNC Symbol;Acc:HGNC:9330]",{"v":2.694225,"d":"2.69"},{"v":11.912299,"d":"11.91"},{"v":0.226171707073504,"d":"0.23"},{"v":-2.14450962806054,"d":"-2.14"},{"v":0.000747840688909784,"d":"0.00"},{"v":0.0170683639586468,"d":"0.02"},"down","yes"]
[78721,0,"chr17","+",7307974,7312455,"ENST00000419711",6,1271,"MSTRG.6394","EIF5A","GO:0003723(RNA binding);GO:0006810(transport);GO:0051028(mRNA transport);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0015031(protein transport);GO:0006412(translation);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005515(protein binding);GO:0006915(apoptotic process);GO:0003746(translation elongation factor activity);GO:0006414(translational elongation);GO:0006406(mRNA export from nucleus);GO:0005643(nuclear pore);GO:0043022(ribosome binding);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0006452(translational frameshifting);GO:0045901(positive regulation of translational elongation);GO:0045905(positive regulation of translational termination);GO:0008284(positive regulation of cell proliferation);GO:0047485(protein N-terminus binding);GO:0005642(annulate lamellae);GO:0006913(nucleocytoplasmic transport);GO:0017070(U6 snRNA binding);GO:0006611(protein export from nucleus);GO:0008612(peptidyl-lysine modification to peptidyl-hypusine);GO:0007204(positive regulation of cytosolic calcium ion concentration);GO:0007568(aging);GO:0010666(positive regulation of cardiac muscle cell apoptotic process);GO:0043065(positive regulation of apoptotic process);GO:0043066(negative regulation of apoptotic process);GO:0051149(positive regulation of muscle cell differentiation);GO:0097067(cellular response to thyroid hormone stimulus);GO:2000379(positive regulation of reactive oxygen species metabolic process);GO:0030425(dendrite);GO:0043025(neuronal cell body)","NA","NA","NA","eukaryotic translation initiation factor 5A [Source:HGNC Symbol;Acc:HGNC:3300]",{"v":1.4679,"d":"1.47"},{"v":6.547712,"d":"6.55"},{"v":0.224185181022012,"d":"0.22"},{"v":-2.15723717790655,"d":"-2.16"},{"v":0.000753301920932751,"d":"0.00"},{"v":0.0171732009348125,"d":"0.02"},"down","yes"]
[75452,0,"chr16","+",71895543,71929010,"ENST00000329908",10,2356,"MSTRG.6105","IST1","GO:0015031(protein transport);GO:0043231(intracellular membrane-bounded organelle);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0051301(cell division);GO:0005829(cytosol);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0007049(cell cycle);GO:0031410(cytoplasmic vesicle);GO:0005813(centrosome);GO:0005815(microtubule organizing center);GO:0030496(midbody);GO:0005576(extracellular region);GO:0045296(cadherin binding);GO:0070062(extracellular exosome);GO:0036258(multivesicular body assembly);GO:0043312(neutrophil degranulation);GO:0019904(protein domain specific binding);GO:0032403(protein complex binding);GO:0035578(azurophil granule lumen);GO:0005635(nuclear envelope);GO:0000910(cytokinesis);GO:0005793(endoplasmic reticulum-Golgi intermediate compartment);GO:0045862(positive regulation of proteolysis);GO:0000785(chromatin);GO:0045184(establishment of protein localization);GO:1904903(ESCRT III complex disassembly);GO:0008104(protein localization);GO:0019076(viral release from host cell);GO:0090543(Flemming body);GO:0090541(MIT domain binding);GO:0009838(abscission);GO:0046745(viral capsid secondary envelopment);GO:0048672(positive regulation of collateral sprouting)","04144(Endocytosis)","K19476","NA","IST1, ESCRT-III associated factor [Source:HGNC Symbol;Acc:HGNC:28977]",{"v":1.235895,"d":"1.24"},{"v":5.454084,"d":"5.45"},{"v":0.226599920353262,"d":"0.23"},{"v":-2.1417807408162,"d":"-2.14"},{"v":0.000755119996262076,"d":"0.00"},{"v":0.0171867285150388,"d":"0.02"},"down","yes"]
[145232,0,"chr4","+",1721519,1738350,"ENST00000484651",10,2715,"MSTRG.11494","TACC3","GO:0005737(cytoplasm);GO:0051301(cell division);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0007049(cell cycle);GO:0000922(spindle pole);GO:0005815(microtubule organizing center);GO:0005819(spindle);GO:0008283(cell proliferation);GO:0021987(cerebral cortex development);GO:0015630(microtubule cytoskeleton);GO:0060236(regulation of mitotic spindle organization);GO:0007091(metaphase/anaphase transition of mitotic cell cycle);GO:1902850(microtubule cytoskeleton organization involved in mitosis)","03013(RNA transport)","NA","NA","transforming acidic coiled-coil containing protein 3 [Source:HGNC Symbol;Acc:HGNC:11524]",{"v":4.879916,"d":"4.88"},{"v":0.835871,"d":"0.84"},{"v":5.83812095407066,"d":"5.84"},{"v":2.5455041008762,"d":"2.55"},{"v":0.000755632393778236,"d":"0.00"},{"v":0.0171867285150388,"d":"0.02"},"up","yes"]
[15479,0,"chr1","-",206913632,206921941,"ENST00000533312",2,587,"MSTRG.1351","FCMR","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005576(extracellular region);GO:0002376(immune system process);GO:0043066(negative regulation of apoptotic process);GO:0006968(cellular defense response)","NA","NA","NA","Fc fragment of IgM receptor [Source:HGNC Symbol;Acc:HGNC:14315]",{"v":1.522801,"d":"1.52"},{"v":7.046474,"d":"7.05"},{"v":0.216108226610926,"d":"0.22"},{"v":-2.21017410244522,"d":"-2.21"},{"v":0.000756729240322301,"d":"0.00"},{"v":0.017191915278413,"d":"0.02"},"down","yes"]
[58082,"j","chr14","-",94376977,94390665,"MSTRG.4639.5",7,3238,"MSTRG.4639","SERPINA1","NA","NA","NA","NA","NA",{"v":5.201112,"d":"5.20"},{"v":22.437799,"d":"22.44"},{"v":0.231801345577612,"d":"0.23"},{"v":-2.10903915385569,"d":"-2.11"},{"v":0.000764106077172443,"d":"0.00"},{"v":0.017306593138317,"d":"0.02"},"down","yes"]
[105529,"j","chr19","+",54449190,54461964,"MSTRG.8421.5",16,3611,"MSTRG.8421","LENG8","NA","NA","NA","NA","NA",{"v":8.873557,"d":"8.87"},{"v":1.546379,"d":"1.55"},{"v":5.73828084835606,"d":"5.74"},{"v":2.52061857957661,"d":"2.52"},{"v":0.000765046274144918,"d":"0.00"},{"v":0.017306593138317,"d":"0.02"},"up","yes"]
[9612,0,"chr1","-",116514535,116571039,"ENST00000369489",6,1098,"MSTRG.834","CD58","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005886(plasma membrane);GO:0031225(anchored component of membrane);GO:0050900(leukocyte migration);GO:0005887(integral component of plasma membrane);GO:0005515(protein binding);GO:0070062(extracellular exosome);GO:0071346(cellular response to interferon-gamma);GO:0071356(cellular response to tumor necrosis factor);GO:0005102(receptor binding);GO:0043312(neutrophil degranulation);GO:2000484(positive regulation of interleukin-8 secretion);GO:0007155(cell adhesion);GO:0009986(cell surface);GO:0030667(secretory granule membrane);GO:0016337(single organismal cell-cell adhesion);GO:0101003(ficolin-1-rich granule membrane);GO:0034113(heterotypic cell-cell adhesion)","04514(Cell adhesion molecules (CAMs));05169(Epstein-Barr virus infection)","K06492","NA","CD58 molecule [Source:HGNC Symbol;Acc:HGNC:1688]",{"v":3.073499,"d":"3.07"},{"v":13.470282,"d":"13.47"},{"v":0.228168868328072,"d":"0.23"},{"v":-2.13182613311439,"d":"-2.13"},{"v":0.000765262274105386,"d":"0.00"},{"v":0.017306593138317,"d":"0.02"},"down","yes"]
[47466,0,"chr12","+",120534812,120576886,"ENST00000413266",17,2671,"MSTRG.3797","RNF10","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0045893(positive regulation of transcription, DNA-templated);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0044212(transcription regulatory region DNA binding);GO:0004842(ubiquitin-protein transferase activity);GO:0051865(protein autoubiquitination);GO:0031643(positive regulation of myelination);GO:0010626(negative regulation of Schwann cell proliferation)","NA","NA","NA","ring finger protein 10 [Source:HGNC Symbol;Acc:HGNC:10055]",{"v":51.148602,"d":"51.15"},{"v":8.993698,"d":"8.99"},{"v":5.6871602760066,"d":"5.69"},{"v":2.50770846301031,"d":"2.51"},{"v":0.000765275368709692,"d":"0.00"},{"v":0.017306593138317,"d":"0.02"},"up","yes"]
[112106,"o","chr2","-",88846693,88866183,"MSTRG.8934.6",4,1303,"MSTRG.8934","AC244205.1","NA","NA","NA","NA","NA",{"v":34.125343,"d":"34.13"},{"v":5.965621,"d":"5.97"},{"v":5.72033372552497,"d":"5.72"},{"v":2.51609931660423,"d":"2.52"},{"v":0.000767009388983496,"d":"0.00"},{"v":0.017326006608682,"d":"0.02"},"up","yes"]
[123688,0,"chr20","+",38472816,38578859,"ENST00000397042",30,8652,"ENSG00000170471","RALGAPB","GO:0005096(GTPase activator activity);GO:0051056(regulation of small GTPase mediated signal transduction);GO:0090630(activation of GTPase activity);GO:0046982(protein heterodimerization activity);GO:0043547(positive regulation of GTPase activity)","NA","NA","NA","Ral GTPase activating protein non-catalytic beta subunit [Source:HGNC Symbol;Acc:HGNC:29221]",{"v":4.92176,"d":"4.92"},{"v":0.861635,"d":"0.86"},{"v":5.71211707973794,"d":"5.71"},{"v":2.51402555020494,"d":"2.51"},{"v":0.000771635310841184,"d":"0.00"},{"v":0.0174106266031076,"d":"0.02"},"up","yes"]
[137765,0,"chr3","-",64010554,64017732,"ENST00000467853",3,4583,"MSTRG.11035","PSMD6","GO:0005515(protein binding);GO:0006508(proteolysis);GO:0000502(proteasome complex);GO:0038095(Fc-epsilon receptor signaling pathway);GO:0005576(extracellular region);GO:0030234(enzyme regulator activity);GO:0043161(proteasome-mediated ubiquitin-dependent protein catabolic process);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0000165(MAPK cascade);GO:0000209(protein polyubiquitination);GO:0002223(stimulatory C-type lectin receptor signaling pathway);GO:0002479(antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent);GO:0006521(regulation of cellular amino acid metabolic process);GO:0010972(negative regulation of G2/M transition of mitotic cell cycle);GO:0016579(protein deubiquitination);GO:0031145(anaphase-promoting complex-dependent catabolic process);GO:0031146(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process);GO:0033209(tumor necrosis factor-mediated signaling pathway);GO:0038061(NIK/NF-kappaB signaling);GO:0043488(regulation of mRNA stability);GO:0043687(post-translational protein modification);GO:0050852(T cell receptor signaling pathway);GO:0051437(positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition);GO:0055085(transmembrane transport);GO:0060071(Wnt signaling pathway, planar cell polarity pathway);GO:0061418(regulation of transcription from RNA polymerase II promoter in response to hypoxia);GO:0090090(negative regulation of canonical Wnt signaling pathway);GO:0090263(positive regulation of canonical Wnt signaling pathway);GO:1902036(regulation of hematopoietic stem cell differentiation);GO:0016887(ATPase activity);GO:0043312(neutrophil degranulation);GO:0051436(negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle);GO:0022624(proteasome accessory complex);GO:0034774(secretory granule lumen);GO:1904813(ficolin-1-rich granule lumen);GO:0005838(proteasome regulatory particle);GO:0050790(regulation of catalytic activity)","03050(Proteasome);05169(Epstein-Barr virus infection)","NA","NA","proteasome 26S subunit, non-ATPase 6 [Source:HGNC Symbol;Acc:HGNC:9564]",{"v":1.228689,"d":"1.23"},{"v":0.203815,"d":"0.20"},{"v":6.02845227289454,"d":"6.03"},{"v":2.59178765638257,"d":"2.59"},{"v":0.000774647664614805,"d":"0.00"},{"v":0.0174586879127537,"d":"0.02"},"up","yes"]
[164979,0,"chr6","-",32190766,32192906,"ENST00000375040",4,1476,"MSTRG.12917","GPSM3","GO:0030695(GTPase regulator activity);GO:0050790(regulation of catalytic activity);GO:0005092(GDP-dissociation inhibitor activity);GO:1900015(regulation of cytokine production involved in inflammatory response);GO:0005737(cytoplasm);GO:0005515(protein binding);GO:0002690(positive regulation of leukocyte chemotaxis);GO:0050729(positive regulation of inflammatory response);GO:1900017(positive regulation of cytokine production involved in inflammatory response);GO:0005886(plasma membrane);GO:0003674(molecular_function);GO:0008150(biological_process);GO:0005575(cellular_component);GO:0006955(immune response)","NA","NA","NA","G protein signaling modulator 3 [Source:HGNC Symbol;Acc:HGNC:13945]",{"v":17.419491,"d":"17.42"},{"v":74.888306,"d":"74.89"},{"v":0.232606289692279,"d":"0.23"},{"v":-2.10403798696198,"d":"-2.10"},{"v":0.000776159464274459,"d":"0.00"},{"v":0.0174728594756121,"d":"0.02"},"down","yes"]
[61113,0,"chr15","-",40287909,40307837,"ENST00000557821",32,4517,"MSTRG.4898","PLCB2","GO:0005622(intracellular);GO:0035556(intracellular signal transduction);GO:0005509(calcium ion binding);GO:0016042(lipid catabolic process);GO:0004435(phosphatidylinositol phospholipase C activity);GO:0004629(phospholipase C activity);GO:0046872(metal ion binding);GO:0016787(hydrolase activity);GO:0007165(signal transduction);GO:0006629(lipid metabolic process);GO:0004871(signal transducer activity);GO:0008081(phosphoric diester hydrolase activity);GO:0005829(cytosol);GO:0043647(inositol phosphate metabolic process);GO:0007223(Wnt signaling pathway, calcium modulating pathway);GO:0007202(activation of phospholipase C activity);GO:0006644(phospholipid metabolic process);GO:0050913(sensory perception of bitter taste);GO:0005737(cytoplasm)","00562(Inositol phosphate metabolism);04015(Rap1 signaling pathway);04310(Wnt signaling pathway);04371(Apelin signaling pathway);04020(Calcium signaling pathway);04070(Phosphatidylinositol signaling system);04072(Phospholipase D signaling pathway);04071(Sphingolipid signaling pathway);04022(cGMP - PKG signaling pathway);04540(Gap junction);04611(Platelet activation);04621(NOD-like receptor signaling pathway);04062(Chemokine signaling pathway);04911(Insulin secretion);04922(Glucagon signaling pathway);04912(GnRH signaling pathway);04915(Estrogen signaling pathway);04921(Oxytocin signaling pathway);04926(Relaxin signaling pathway);04918(Thyroid hormone synthesis);04919(Thyroid hormone signaling pathway);04916(Melanogenesis);04924(Renin secretion);04925(Aldosterone synthesis and secretion);04927(Cortisol synthesis and secretion);04261(Adrenergic signaling in cardiomyocytes);04270(Vascular smooth muscle contraction);04970(Salivary secretion);04971(Gastric acid secretion);04972(Pancreatic secretion);04973(Carbohydrate digestion and absorption);04961(Endocrine and other factor-regulated calcium reabsorption);04724(Glutamatergic synapse);04725(Cholinergic synapse);04728(Dopaminergic synapse);04726(Serotonergic synapse);04720(Long-term potentiation);04730(Long-term depression);04723(Retrograde endocannabinoid signaling);04742(Taste transduction);04750(Inflammatory mediator regulation of TRP channels);04713(Circadian entrainment);05200(Pathways in cancer);05010(Alzheimer's disease);05016(Huntington's disease);04933(AGE-RAGE signaling pathway in diabetic complications);05146(Amoebiasis);05142(Chagas disease (American trypanosomiasis));05143(African trypanosomiasis)","K05858","EC:3.1.4.11","phospholipase C beta 2 [Source:HGNC Symbol;Acc:HGNC:9055]",{"v":5.255591,"d":"5.26"},{"v":0.916111,"d":"0.92"},{"v":5.73684957390535,"d":"5.74"},{"v":2.52025868953843,"d":"2.52"},{"v":0.000784263343983977,"d":"0.00"},{"v":0.0176352307394943,"d":"0.02"},"up","yes"]
[195031,0,"chr9","+",137078141,137084539,"ENST00000360271",7,3201,"ENSG00000197355","UAP1L1","GO:0016740(transferase activity);GO:0008152(metabolic process);GO:0016779(nucleotidyltransferase activity);GO:0070569(uridylyltransferase activity);GO:0005829(cytosol);GO:0003977(UDP-N-acetylglucosamine diphosphorylase activity);GO:0006048(UDP-N-acetylglucosamine biosynthetic process)","00520(Amino sugar and nucleotide sugar metabolism)","NA","NA","UDP-N-acetylglucosamine pyrophosphorylase 1 like 1 [Source:HGNC Symbol;Acc:HGNC:28082]",{"v":2.607727,"d":"2.61"},{"v":0.442035,"d":"0.44"},{"v":5.89936769712806,"d":"5.90"},{"v":2.5605603325927,"d":"2.56"},{"v":0.000786842488747556,"d":"0.00"},{"v":0.0176731432092357,"d":"0.02"},"up","yes"]
[94326,0,"chr19","+",1438386,1440494,"ENST00000592588",4,510,"MSTRG.7611","RPS15","GO:0003723(RNA binding);GO:0030529(intracellular ribonucleoprotein complex);GO:0003735(structural constituent of ribosome);GO:0006412(translation);GO:0005840(ribosome);GO:0015935(small ribosomal subunit);GO:0005634(nucleus);GO:0016020(membrane);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0022627(cytosolic small ribosomal subunit);GO:0005654(nucleoplasm);GO:0005925(focal adhesion);GO:0006364(rRNA processing);GO:0042274(ribosomal small subunit biogenesis);GO:0000028(ribosomal small subunit assembly);GO:0005829(cytosol);GO:0006413(translational initiation);GO:0000184(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay);GO:0019083(viral transcription);GO:0001649(osteoblast differentiation);GO:0006614(SRP-dependent cotranslational protein targeting to membrane);GO:0000056(ribosomal small subunit export from nucleus)","03010(Ribosome)","K02958","NA","ribosomal protein S15 [Source:HGNC Symbol;Acc:HGNC:10388]",{"v":30.335764,"d":"30.34"},{"v":130.304825,"d":"130.30"},{"v":0.232806145129315,"d":"0.23"},{"v":-2.10279895489469,"d":"-2.10"},{"v":0.000787897413682582,"d":"0.00"},{"v":0.0176767732675181,"d":"0.02"},"down","yes"]
[152514,0,"chr4","-",182890255,182917594,"ENST00000438320",6,1972,"MSTRG.11927","DCTD","GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0016787(hydrolase activity);GO:0003824(catalytic activity);GO:0005515(protein binding);GO:0008152(metabolic process);GO:0042802(identical protein binding);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0004132(dCMP deaminase activity);GO:0006220(pyrimidine nucleotide metabolic process);GO:0015949(nucleobase-containing small molecule interconversion);GO:0009165(nucleotide biosynthetic process);GO:0006226(dUMP biosynthetic process);GO:0006231(dTMP biosynthetic process)","00240(Pyrimidine metabolism)","K01493","EC:3.5.4.12","dCMP deaminase [Source:HGNC Symbol;Acc:HGNC:2710]",{"v":0.489197,"d":"0.49"},{"v":2.234791,"d":"2.23"},{"v":0.218900559381168,"d":"0.22"},{"v":-2.19165245368323,"d":"-2.19"},{"v":0.000797023684727511,"d":"0.00"},{"v":0.0178612736957961,"d":"0.02"},"down","yes"]
[158950,0,"chr5","+",139293778,139330441,"ENST00000618441",15,4018,"MSTRG.12384","MATR3","GO:0005634(nucleus);GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0008270(zinc ion binding);GO:0016020(membrane);GO:0046872(metal ion binding);GO:0005515(protein binding);GO:0042802(identical protein binding);GO:0016363(nuclear matrix);GO:0005198(structural molecule activity);GO:0010608(posttranscriptional regulation of gene expression);GO:0005637(nuclear inner membrane)","NA","NA","NA","matrin 3 [Source:HGNC Symbol;Acc:HGNC:6912]",{"v":2.47417,"d":"2.47"},{"v":0.424311,"d":"0.42"},{"v":5.83102959857275,"d":"5.83"},{"v":2.54375064596562,"d":"2.54"},{"v":0.000803114063126,"d":"0.00"},{"v":0.0179773994130512,"d":"0.02"},"up","yes"]
[61172,"j","chr15","+",40441187,40468228,"MSTRG.4902.2",7,4528,"MSTRG.4902","BAHD1","NA","NA","NA","NA","NA",{"v":4.157131,"d":"4.16"},{"v":0.723308,"d":"0.72"},{"v":5.74738700525917,"d":"5.75"},{"v":2.52290619755856,"d":"2.52"},{"v":0.000810484404423394,"d":"0.00"},{"v":0.0181114152301627,"d":"0.02"},"up","yes"]
[17529,0,"chr1","+",244051283,244057476,"ENST00000358704",2,3851,"MSTRG.1487","ZBTB18","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0005654(nucleoplasm);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0045171(intercellular bridge);GO:0015630(microtubule cytoskeleton);GO:0005515(protein binding);GO:0007275(multicellular organism development);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0043565(sequence-specific DNA binding);GO:0045892(negative regulation of transcription, DNA-templated);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0007519(skeletal muscle tissue development);GO:0000228(nuclear chromosome)","NA","NA","NA","zinc finger and BTB domain containing 18 [Source:HGNC Symbol;Acc:HGNC:13030]",{"v":0.867724,"d":"0.87"},{"v":3.779763,"d":"3.78"},{"v":0.229571007494385,"d":"0.23"},{"v":-2.12298763922023,"d":"-2.12"},{"v":0.000810931569331119,"d":"0.00"},{"v":0.0181114152301627,"d":"0.02"},"down","yes"]
[14618,0,"chr1","+",198639095,198757283,"ENST00000348564",30,4626,"MSTRG.1281","PTPRC","GO:0004725(protein tyrosine phosphatase activity);GO:0035335(peptidyl-tyrosine dephosphorylation);GO:0050852(T cell receptor signaling pathway);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0006470(protein dephosphorylation);GO:0016787(hydrolase activity);GO:0016791(phosphatase activity);GO:0016311(dephosphorylation);GO:0004721(phosphoprotein phosphatase activity);GO:0010332(response to gamma radiation);GO:0005887(integral component of plasma membrane);GO:0009986(cell surface)","04514(Cell adhesion molecules (CAMs));04660(T cell receptor signaling pathway);04666(Fc gamma R-mediated phagocytosis);05340(Primary immunodeficiency)","K06478","EC:3.1.3.48","protein tyrosine phosphatase, receptor type C [Source:HGNC Symbol;Acc:HGNC:9666]",{"v":207.131027,"d":"207.13"},{"v":36.819588,"d":"36.82"},{"v":5.62556612529179,"d":"5.63"},{"v":2.49199828833914,"d":"2.49"},{"v":0.000816119055765653,"d":"0.00"},{"v":0.0182067236476784,"d":"0.02"},"up","yes"]
[43297,0,"chr12","+",57128499,57213351,"ENST00000243077",89,14897,"MSTRG.3478","LRP1","GO:0005730(nucleolus);GO:0005829(cytosol);GO:0005509(calcium ion binding);GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0046872(metal ion binding);GO:0005765(lysosomal membrane);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0007275(multicellular organism development);GO:0005905(clathrin-coated pit);GO:0005925(focal adhesion);GO:0006898(receptor-mediated endocytosis);GO:0005887(integral component of plasma membrane);GO:0006897(endocytosis);GO:0042953(lipoprotein transport);GO:0004872(receptor activity);GO:1904646(cellular response to amyloid-beta);GO:0030666(endocytic vesicle membrane);GO:0001523(retinoid metabolic process);GO:0043235(receptor complex);GO:0030178(negative regulation of Wnt signaling pathway);GO:0010942(positive regulation of cell death);GO:0014912(negative regulation of smooth muscle cell migration);GO:0034185(apolipoprotein binding);GO:0010875(positive regulation of cholesterol efflux);GO:0097242(amyloid-beta clearance);GO:0005041(low-density lipoprotein receptor activity);GO:0045807(positive regulation of endocytosis);GO:0051246(regulation of protein metabolic process);GO:1900223(positive regulation of amyloid-beta clearance);GO:1905167(positive regulation of lysosomal protein catabolic process);GO:0032374(regulation of cholesterol transport);GO:0032956(regulation of actin cytoskeleton organization);GO:0002265(astrocyte activation involved in immune response);GO:0035909(aorta morphogenesis);GO:0045732(positive regulation of protein catabolic process);GO:0005044(scavenger receptor activity);GO:0045056(transcytosis);GO:1903078(positive regulation of protein localization to plasma membrane);GO:0032403(protein complex binding);GO:0070325(lipoprotein particle receptor binding);GO:0006629(lipid metabolic process);GO:0098797(plasma membrane protein complex);GO:0002020(protease binding);GO:0016964(alpha-2 macroglobulin receptor activity);GO:0030226(apolipoprotein receptor activity);GO:0032050(clathrin heavy chain binding);GO:0042954(lipoprotein transporter activity);GO:0043395(heparan sulfate proteoglycan binding);GO:0006909(phagocytosis);GO:0007205(protein kinase C-activating G-protein coupled receptor signaling pathway);GO:0007568(aging);GO:0008283(cell proliferation);GO:0010715(regulation of extracellular matrix disassembly);GO:0010977(negative regulation of neuron projection development);GO:0021987(cerebral cortex development);GO:0031623(receptor internalization);GO:0032092(positive regulation of protein binding);GO:0032370(positive regulation of lipid transport);GO:0032429(regulation of phospholipase A2 activity);GO:0042157(lipoprotein metabolic process);GO:0043277(apoptotic cell clearance);GO:0043524(negative regulation of neuron apoptotic process);GO:0051222(positive regulation of protein transport);GO:2000587(negative regulation of platelet-derived growth factor receptor-beta signaling pathway);GO:0005768(endosome);GO:0005769(early endosome);GO:0016323(basolateral plasma membrane);GO:0030136(clathrin-coated vesicle);GO:0030425(dendrite);GO:0043025(neuronal cell body)","04979(Cholesterol metabolism);05010(Alzheimer's disease);05144(Malaria)","K04550","NA","LDL receptor related protein 1 [Source:HGNC Symbol;Acc:HGNC:6692]",{"v":10.331453,"d":"10.33"},{"v":1.834419,"d":"1.83"},{"v":5.63200283032393,"d":"5.63"},{"v":2.49364805899177,"d":"2.49"},{"v":0.000819348060224369,"d":"0.00"},{"v":0.0182581750177025,"d":"0.02"},"up","yes"]
[102947,0,"chr19","-",45818913,45863130,"ENST00000599460",22,5449,"MSTRG.8238","SYMPK","GO:0006397(mRNA processing);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0007155(cell adhesion);GO:0005886(plasma membrane);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0030054(cell junction);GO:0005923(bicellular tight junction);GO:0006369(termination of RNA polymerase II transcription);GO:0031124(mRNA 3'-end processing);GO:0000398(mRNA splicing, via spliceosome);GO:0006406(mRNA export from nucleus);GO:0006378(mRNA polyadenylation);GO:0097165(nuclear stress granule);GO:0035307(positive regulation of protein dephosphorylation)","03015(mRNA surveillance pathway);04530(Tight junction)","NA","NA","symplekin [Source:HGNC Symbol;Acc:HGNC:22935]",{"v":0.255761,"d":"0.26"},{"v":1.140477,"d":"1.14"},{"v":0.224257920150954,"d":"0.22"},{"v":-2.15676915696365,"d":"-2.16"},{"v":0.000822457273915284,"d":"0.00"},{"v":0.0183068442477341,"d":"0.02"},"down","yes"]
[56446,0,"chr14","+",71932439,72562476,"ENST00000553525",18,2005,"ENSG00000182732","RGS6","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0007186(G-protein coupled receptor signaling pathway);GO:0035556(intracellular signal transduction);GO:0004871(signal transducer activity);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0005834(heterotrimeric G-protein complex);GO:0005096(GTPase activator activity);GO:0043547(positive regulation of GTPase activity);GO:0019898(extrinsic component of membrane);GO:0009968(negative regulation of signal transduction);GO:0008277(regulation of G-protein coupled receptor protein signaling pathway)","NA","NA","NA","regulator of G protein signaling 6 [Source:HGNC Symbol;Acc:HGNC:10002]",{"v":0.365959,"d":"0.37"},{"v":1.687395,"d":"1.69"},{"v":0.216878087229131,"d":"0.22"},{"v":-2.20504380048888,"d":"-2.21"},{"v":0.000824826682203379,"d":"0.00"},{"v":0.0183389554915061,"d":"0.02"},"down","yes"]
[141611,0,"chr3","-",149738470,149752499,"ENST00000473414",5,3706,"ENSG00000114744","COMMD2","GO:0005737(cytoplasm);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0005515(protein binding)","NA","NA","NA","COMM domain containing 2 [Source:HGNC Symbol;Acc:HGNC:24993]",{"v":1.054884,"d":"1.05"},{"v":4.554378,"d":"4.55"},{"v":0.231619773325798,"d":"0.23"},{"v":-2.11016967376501,"d":"-2.11"},{"v":0.000838976131364622,"d":"0.00"},{"v":0.0186326146884884,"d":"0.02"},"down","yes"]
[178528,"o","chr7","+",128640482,128652334,"MSTRG.13953.1",6,1998,"MSTRG.13953","AC018638.4","NA","NA","NA","NA","NA",{"v":7.983383,"d":"7.98"},{"v":1.393252,"d":"1.39"},{"v":5.73003519822688,"d":"5.73"},{"v":2.51854400113775,"d":"2.52"},{"v":0.00084064590550628,"d":"0.00"},{"v":0.0186487681369487,"d":"0.02"},"up","yes"]
[167336,0,"chr6","+",75601509,75715904,"ENST00000370010",23,4644,"MSTRG.13141","SENP6","GO:0005634(nucleus);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0016787(hydrolase activity);GO:0008233(peptidase activity);GO:0008234(cysteine-type peptidase activity);GO:0006508(proteolysis);GO:0005515(protein binding);GO:0016925(protein sumoylation);GO:0090169(regulation of spindle assembly);GO:0090234(regulation of kinetochore assembly);GO:0016926(protein desumoylation);GO:0016929(SUMO-specific protease activity);GO:0070646(protein modification by small protein removal)","NA","NA","NA","SUMO1/sentrin specific peptidase 6 [Source:HGNC Symbol;Acc:HGNC:20944]",{"v":5.09918,"d":"5.10"},{"v":0.899203,"d":"0.90"},{"v":5.6707773439368,"d":"5.67"},{"v":2.50354651177671,"d":"2.50"},{"v":0.000845957899672104,"d":"0.00"},{"v":0.0187455934140107,"d":"0.02"},"up","yes"]
[201193,0,"chrX","+",154398372,154402339,"ENST00000344746",6,2278,"MSTRG.15511","RPL10","GO:0003723(RNA binding);GO:0016020(membrane);GO:0006412(translation);GO:0030529(intracellular ribonucleoprotein complex);GO:0005622(intracellular);GO:0003735(structural constituent of ribosome);GO:0005840(ribosome);GO:0005515(protein binding);GO:0000027(ribosomal large subunit assembly);GO:0005829(cytosol);GO:0005783(endoplasmic reticulum);GO:0043234(protein complex);GO:0006413(translational initiation);GO:0006364(rRNA processing);GO:0005634(nucleus);GO:0000184(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay);GO:0019083(viral transcription);GO:0006614(SRP-dependent cotranslational protein targeting to membrane);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0022625(cytosolic large ribosomal subunit);GO:0005790(smooth endoplasmic reticulum);GO:0043066(negative regulation of apoptotic process)","03010(Ribosome)","K02866","NA","ribosomal protein L10 [Source:HGNC Symbol;Acc:HGNC:10298]",{"v":76.553398,"d":"76.55"},{"v":324.395172,"d":"324.40"},{"v":0.235988092942394,"d":"0.24"},{"v":-2.083214026344,"d":"-2.08"},{"v":0.000849039596215538,"d":"0.00"},{"v":0.0187928361632137,"d":"0.02"},"down","yes"]
[149203,0,"chr4","+",88007668,88077777,"ENST00000237596",15,5056,"ENSG00000118762","PKD2","GO:0008285(negative regulation of cell proliferation);GO:0071158(positive regulation of cell cycle arrest);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0005737(cytoplasm);GO:2000134(negative regulation of G1/S transition of mitotic cell cycle);GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0046872(metal ion binding);GO:0005783(endoplasmic reticulum);GO:0005509(calcium ion binding);GO:0005789(endoplasmic reticulum membrane);GO:0005244(voltage-gated ion channel activity);GO:0005267(potassium channel activity);GO:0006811(ion transport);GO:0006813(potassium ion transport);GO:0034765(regulation of ion transmembrane transport);GO:0071805(potassium ion transmembrane transport);GO:0005886(plasma membrane);GO:0042995(cell projection);GO:0005515(protein binding);GO:0006816(calcium ion transport);GO:0030659(cytoplasmic vesicle membrane);GO:0031410(cytoplasmic vesicle);GO:0005262(calcium channel activity);GO:0070588(calcium ion transmembrane transport);GO:0042802(identical protein binding);GO:0005887(integral component of plasma membrane);GO:0060078(regulation of postsynaptic membrane potential);GO:0005929(cilium);GO:0070062(extracellular exosome);GO:0007507(heart development);GO:0016323(basolateral plasma membrane);GO:0060170(ciliary membrane);GO:0042803(protein homodimerization activity);GO:0030027(lamellipodium);GO:0044325(ion channel binding);GO:0035725(sodium ion transmembrane transport);GO:0051289(protein homotetramerization);GO:0001947(heart looping);GO:0007368(determination of left/right symmetry);GO:0021510(spinal cord development);GO:0051209(release of sequestered calcium ion into cytosol);GO:0051117(ATPase binding);GO:0005102(receptor binding);GO:0005911(cell-cell junction);GO:0060315(negative regulation of ryanodine-sensitive calcium-release channel activity);GO:0051298(centrosome duplication);GO:0050982(detection of mechanical stimulus);GO:0051219(phosphoprotein binding);GO:0001889(liver development);GO:0071320(cellular response to cAMP);GO:0071277(cellular response to calcium ion);GO:0045429(positive regulation of nitric oxide biosynthetic process);GO:0042805(actinin binding);GO:0005249(voltage-gated potassium channel activity);GO:0071910(determination of liver left/right asymmetry);GO:0072686(mitotic spindle);GO:0005248(voltage-gated sodium channel activity);GO:0036064(ciliary basal body);GO:0031514(motile cilium);GO:0021915(neural tube development);GO:0015271(outward rectifier potassium channel activity);GO:0072177(mesonephric duct development);GO:0031659(positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle);GO:0042127(regulation of cell proliferation);GO:0034614(cellular response to reactive oxygen species);GO:0001658(branching involved in ureteric bud morphogenesis);GO:0007050(cell cycle arrest);GO:0090279(regulation of calcium ion import);GO:0007259(JAK-STAT cascade);GO:0061333(renal tubule morphogenesis);GO:0008092(cytoskeletal protein binding);GO:0030814(regulation of cAMP metabolic process);GO:0072075(metanephric mesenchyme development);GO:0072284(metanephric S-shaped body morphogenesis);GO:0072218(metanephric ascending thin limb development);GO:0060674(placenta blood vessel development);GO:0097730(non-motile cilium);GO:0005245(voltage-gated calcium channel activity);GO:0001892(embryonic placenta development);GO:0042994(cytoplasmic sequestering of transcription factor);GO:0072164(mesonephric tubule development);GO:0002133(polycystin complex);GO:0009925(basal plasma membrane);GO:0031941(filamentous actin);GO:0015267(channel activity);GO:0022843(voltage-gated cation channel activity);GO:0043398(HLH domain binding);GO:0048763(calcium-induced calcium release activity);GO:0051371(muscle alpha-actinin binding);GO:0051393(alpha-actinin binding);GO:0001822(kidney development);GO:0003127(detection of nodal flow);GO:0006874(cellular calcium ion homeostasis);GO:0007204(positive regulation of cytosolic calcium ion concentration);GO:0010628(positive regulation of gene expression);GO:0031587(positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity);GO:0035502(metanephric part of ureteric bud development);GO:0035904(aorta development);GO:0061441(renal artery morphogenesis);GO:0071464(cellular response to hydrostatic pressure);GO:0071470(cellular response to osmotic stress);GO:0071498(cellular response to fluid shear stress);GO:0072001(renal system development);GO:0072208(metanephric smooth muscle tissue development);GO:0072214(metanephric cortex development);GO:0072219(metanephric cortical collecting duct development);GO:0072235(metanephric distal tubule development);GO:0045180(basal cortex);GO:0071458(integral component of cytoplasmic side of endoplasmic reticulum membrane);GO:0071556(integral component of lumenal side of endoplasmic reticulum membrane)","NA","NA","NA","polycystin 2, transient receptor potential cation channel [Source:HGNC Symbol;Acc:HGNC:9009]",{"v":0.974606,"d":"0.97"},{"v":0.162932,"d":"0.16"},{"v":5.98167333611568,"d":"5.98"},{"v":2.5805491258979,"d":"2.58"},{"v":0.000861810769488986,"d":"0.00"},{"v":0.0190542028007241,"d":"0.02"},"up","yes"]
[60758,0,"chr15","-",34233259,34336844,"ENST00000560611",25,4239,"MSTRG.4885","SLC12A6","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005215(transporter activity);GO:0055085(transmembrane transport);GO:0006811(ion transport);GO:0005887(integral component of plasma membrane);GO:0015293(symporter activity);GO:0006813(potassium ion transport);GO:0005886(plasma membrane);GO:0071805(potassium ion transmembrane transport);GO:0015377(cation:chloride symporter activity);GO:0015379(potassium:chloride symporter activity);GO:0071477(cellular hypotonic salinity response);GO:1902476(chloride transmembrane transport);GO:0022820(potassium ion symporter activity);GO:0016323(basolateral plasma membrane);GO:0007268(chemical synaptic transmission);GO:0001525(angiogenesis)","NA","NA","NA","solute carrier family 12 member 6 [Source:HGNC Symbol;Acc:HGNC:10914]",{"v":18.453615,"d":"18.45"},{"v":3.29619,"d":"3.30"},{"v":5.59846823150364,"d":"5.60"},{"v":2.4850321526877,"d":"2.49"},{"v":0.000863531647418727,"d":"0.00"},{"v":0.0190709422311627,"d":"0.02"},"up","yes"]
[13770,0,"chr1","-",173938411,173993072,"ENST00000367694",19,3775,"ENSG00000135870","RC3H1","GO:0003730(mRNA 3'-UTR binding);GO:0003723(RNA binding);GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0016567(protein ubiquitination);GO:0010608(posttranscriptional regulation of gene expression);GO:0050863(regulation of T cell activation);GO:0000288(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay);GO:0000932(P-body);GO:0061158(3'-UTR-mediated mRNA destabilization);GO:0071347(cellular response to interleukin-1);GO:0061014(positive regulation of mRNA catabolic process);GO:0035613(RNA stem-loop binding);GO:0061630(ubiquitin protein ligase activity);GO:0010494(cytoplasmic stress granule);GO:0046007(negative regulation of activated T cell proliferation);GO:0002634(regulation of germinal center formation);GO:0033962(cytoplasmic mRNA processing body assembly);GO:0003729(mRNA binding);GO:0000956(nuclear-transcribed mRNA catabolic process);GO:0001782(B cell homeostasis);GO:0002635(negative regulation of germinal center formation);GO:0010468(regulation of gene expression);GO:0030889(negative regulation of B cell proliferation);GO:0042098(T cell proliferation);GO:0042129(regulation of T cell proliferation);GO:0043029(T cell homeostasis);GO:0043488(regulation of mRNA stability);GO:0045623(negative regulation of T-helper cell differentiation);GO:0048535(lymph node development);GO:0048536(spleen development);GO:0050856(regulation of T cell receptor signaling pathway);GO:0061470(T follicular helper cell differentiation);GO:1901224(positive regulation of NIK/NF-kappaB signaling)","NA","NA","NA","ring finger and CCCH-type domains 1 [Source:HGNC Symbol;Acc:HGNC:29434]",{"v":4.722368,"d":"4.72"},{"v":0.831313,"d":"0.83"},{"v":5.68061367980532,"d":"5.68"},{"v":2.5060467932841,"d":"2.51"},{"v":0.000865146150366948,"d":"0.00"},{"v":0.019085297685018,"d":"0.02"},"up","yes"]
[41195,"j","chr12","+",49127782,49186065,"MSTRG.3346.1",2,1232,"MSTRG.3346","AC011603.2","NA","NA","NA","NA","NA",{"v":1.059481,"d":"1.06"},{"v":4.672835,"d":"4.67"},{"v":0.226731951802278,"d":"0.23"},{"v":-2.14094038021584,"d":"-2.14"},{"v":0.000868017003859273,"d":"0.00"},{"v":0.0191273056485159,"d":"0.02"},"down","yes"]
[150566,0,"chr4","+",122152333,122362752,"ENST00000264501",86,15896,"MSTRG.11834","KIAA1109","GO:0005634(nucleus);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005515(protein binding);GO:0001558(regulation of cell growth);GO:0030856(regulation of epithelial cell differentiation)","NA","NA","NA","KIAA1109 [Source:HGNC Symbol;Acc:HGNC:26953]",{"v":5.690542,"d":"5.69"},{"v":1.017831,"d":"1.02"},{"v":5.59085152643219,"d":"5.59"},{"v":2.48306803251427,"d":"2.48"},{"v":0.000870813465152568,"d":"0.00"},{"v":0.019167582701267,"d":"0.02"},"up","yes"]
[164140,0,"chr6","+",30720201,30725426,"ENST00000327892",4,2670,"MSTRG.12828","TUBB","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005525(GTP binding);GO:0000166(nucleotide binding);GO:0003924(GTPase activity);GO:0015630(microtubule cytoskeleton);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0005200(structural constituent of cytoskeleton);GO:0005874(microtubule);GO:0005576(extracellular region);GO:0007017(microtubule-based process);GO:0070062(extracellular exosome);GO:0000086(G2/M transition of mitotic cell cycle);GO:0010389(regulation of G2/M transition of mitotic cell cycle);GO:0097711(ciliary basal body docking);GO:0031012(extracellular matrix);GO:0043312(neutrophil degranulation);GO:0035578(azurophil granule lumen);GO:0036464(cytoplasmic ribonucleoprotein granule);GO:0006928(movement of cell or subcellular component);GO:0031625(ubiquitin protein ligase binding);GO:0042288(MHC class I protein binding);GO:0005198(structural molecule activity);GO:0019904(protein domain specific binding);GO:0032403(protein complex binding);GO:0032794(GTPase activating protein binding);GO:0009987(cellular process);GO:0030705(cytoskeleton-dependent intracellular transport);GO:0042267(natural killer cell mediated cytotoxicity);GO:0051225(spindle assembly);GO:0051301(cell division);GO:0005641(nuclear envelope lumen);GO:0043234(protein complex);GO:0044297(cell body);GO:0045121(membrane raft);GO:0007010(cytoskeleton organization)","04145(Phagosome);04540(Gap junction);05130(Pathogenic Escherichia coli infection)","K07375","NA","tubulin beta class I [Source:HGNC Symbol;Acc:HGNC:20778]",{"v":10.962707,"d":"10.96"},{"v":46.27372,"d":"46.27"},{"v":0.236909999887625,"d":"0.24"},{"v":-2.07758899937462,"d":"-2.08"},{"v":0.000880819617930404,"d":"0.00"},{"v":0.0193488538844232,"d":"0.02"},"down","yes"]
[37262,"j","chr12","+",752576,912051,"MSTRG.3007.1",26,10660,"MSTRG.3007","WNK1","NA","NA","NA","NA","NA",{"v":6.504741,"d":"6.50"},{"v":1.164729,"d":"1.16"},{"v":5.58476778718483,"d":"5.58"},{"v":2.48149729516846,"d":"2.48"},{"v":0.000881496022540901,"d":"0.00"},{"v":0.0193488538844232,"d":"0.02"},"up","yes"]
[17116,0,"chr1","-",234604269,234609525,"ENST00000366609",2,4663,"MSTRG.1473","IRF2BP2","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0005654(nucleoplasm);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated)","NA","NA","NA","interferon regulatory factor 2 binding protein 2 [Source:HGNC Symbol;Acc:HGNC:21729]",{"v":0.611784,"d":"0.61"},{"v":2.642787,"d":"2.64"},{"v":0.231491981760165,"d":"0.23"},{"v":-2.11096587148904,"d":"-2.11"},{"v":0.000881982322809263,"d":"0.00"},{"v":0.0193488538844232,"d":"0.02"},"down","yes"]
[41551,0,"chr12","+",50505107,50748667,"ENST00000301180",38,8593,"MSTRG.3370","DIP2B","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0003824(catalytic activity);GO:0008152(metabolic process);GO:0003674(molecular_function);GO:0008150(biological_process);GO:0070062(extracellular exosome)","NA","NA","NA","disco interacting protein 2 homolog B [Source:HGNC Symbol;Acc:HGNC:29284]",{"v":11.848239,"d":"11.85"},{"v":2.129021,"d":"2.13"},{"v":5.56511138217988,"d":"5.57"},{"v":2.47641056248377,"d":"2.48"},{"v":0.000894933470636077,"d":"0.00"},{"v":0.0196112331306165,"d":"0.02"},"up","yes"]
[193340,0,"chr9","+",125261832,125367207,"ENST00000470056",25,8923,"ENSG00000165219","GAPVD1","GO:0007165(signal transduction);GO:0043087(regulation of GTPase activity);GO:0016020(membrane);GO:0005829(cytosol);GO:0043547(positive regulation of GTPase activity);GO:0005096(GTPase activator activity);GO:0005085(guanyl-nucleotide exchange factor activity);GO:0032794(GTPase activating protein binding);GO:0051223(regulation of protein transport);GO:0005768(endosome);GO:0045296(cadherin binding);GO:0006897(endocytosis);GO:0017112(Rab guanyl-nucleotide exchange factor activity);GO:0061024(membrane organization)","NA","NA","NA","GTPase activating protein and VPS9 domains 1 [Source:HGNC Symbol;Acc:HGNC:23375]",{"v":3.047906,"d":"3.05"},{"v":0.543729,"d":"0.54"},{"v":5.60556085844235,"d":"5.61"},{"v":2.48685872757359,"d":"2.49"},{"v":0.000903288534328551,"d":"0.00"},{"v":0.019768102357288,"d":"0.02"},"up","yes"]
[195029,0,"chr9","+",137077501,137084538,"ENST00000409858",9,3365,"ENSG00000197355","UAP1L1","GO:0016740(transferase activity);GO:0008152(metabolic process);GO:0016779(nucleotidyltransferase activity);GO:0070569(uridylyltransferase activity);GO:0005829(cytosol);GO:0003977(UDP-N-acetylglucosamine diphosphorylase activity);GO:0006048(UDP-N-acetylglucosamine biosynthetic process)","00520(Amino sugar and nucleotide sugar metabolism)","K00972","EC:2.7.7.23;EC:2.7.7.83","UDP-N-acetylglucosamine pyrophosphorylase 1 like 1 [Source:HGNC Symbol;Acc:HGNC:28082]",{"v":0.388978,"d":"0.39"},{"v":1.718902,"d":"1.72"},{"v":0.226294460068113,"d":"0.23"},{"v":-2.14372682857726,"d":"-2.14"},{"v":0.000904092416365282,"d":"0.00"},{"v":0.019768102357288,"d":"0.02"},"down","yes"]
[179559,"j","chr7","+",142786321,142793369,"MSTRG.14056.10",6,2237,"MSTRG.14056","AC245427.1","NA","NA","NA","NA","NA",{"v":1.773693,"d":"1.77"},{"v":7.56719,"d":"7.57"},{"v":0.234392555228559,"d":"0.23"},{"v":-2.09300134724924,"d":"-2.09"},{"v":0.000905088979972861,"d":"0.00"},{"v":0.019768102357288,"d":"0.02"},"down","yes"]
[2059,0,"chr1","-",16625375,16644672,"ENST00000635081",10,1904,"ENSG00000215908","CROCCP2","NA","NA","NA","NA","ciliary rootlet coiled-coil, rootletin pseudogene 2 [Source:HGNC Symbol;Acc:HGNC:28170]",{"v":3.026611,"d":"3.03"},{"v":0.516213,"d":"0.52"},{"v":5.86310495861205,"d":"5.86"},{"v":2.55166488342955,"d":"2.55"},{"v":0.000907991134953217,"d":"0.00"},{"v":0.0198096235705119,"d":"0.02"},"up","yes"]
[150190,0,"chr4","+",112297343,112442606,"ENST00000504176",15,5203,"MSTRG.11800","ALPK1","GO:0004674(protein serine/threonine kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0005737(cytoplasm)","NA","NA","NA","alpha kinase 1 [Source:HGNC Symbol;Acc:HGNC:20917]",{"v":0.372435,"d":"0.37"},{"v":1.61285,"d":"1.61"},{"v":0.230917320271569,"d":"0.23"},{"v":-2.1145517063888,"d":"-2.11"},{"v":0.000914156832436734,"d":"0.00"},{"v":0.019922175550945,"d":"0.02"},"down","yes"]
[179996,0,"chr7","+",149872968,149880698,"ENST00000615196",4,2727,"MSTRG.14120","ATP6V0E2","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0015078(hydrogen ion transmembrane transporter activity);GO:0015991(ATP hydrolysis coupled proton transport);GO:0033179(proton-transporting V-type ATPase, V0 domain);GO:0006810(transport);GO:0016787(hydrolase activity);GO:0006811(ion transport);GO:0015992(proton transport);GO:0034220(ion transmembrane transport);GO:0010008(endosome membrane);GO:0030670(phagocytic vesicle membrane);GO:0042625(ATPase coupled ion transmembrane transporter activity);GO:0007035(vacuolar acidification);GO:0008286(insulin receptor signaling pathway);GO:0016049(cell growth);GO:0016241(regulation of macroautophagy);GO:0033572(transferrin transport);GO:0090383(phagosome acidification);GO:0046961(proton-transporting ATPase activity, rotational mechanism)","00190(Oxidative phosphorylation);04145(Phagosome);04966(Collecting duct acid secretion);04721(Synaptic vesicle cycle);05323(Rheumatoid arthritis);05110(Vibrio cholerae infection);05120(Epithelial cell signaling in Helicobacter pylori infection)","K02153","NA","ATPase H+ transporting V0 subunit e2 [Source:HGNC Symbol;Acc:HGNC:21723]",{"v":0.305259,"d":"0.31"},{"v":1.389938,"d":"1.39"},{"v":0.219620587393107,"d":"0.22"},{"v":-2.18691479492593,"d":"-2.19"},{"v":0.000921601583252869,"d":"0.00"},{"v":0.0200402770652833,"d":"0.02"},"down","yes"]
[179995,0,"chr7","+",149872968,149880693,"ENST00000456496",4,2722,"MSTRG.14120","ATP6V0E2","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0015078(hydrogen ion transmembrane transporter activity);GO:0015991(ATP hydrolysis coupled proton transport);GO:0033179(proton-transporting V-type ATPase, V0 domain);GO:0006810(transport);GO:0016787(hydrolase activity);GO:0006811(ion transport);GO:0015992(proton transport);GO:0034220(ion transmembrane transport);GO:0010008(endosome membrane);GO:0030670(phagocytic vesicle membrane);GO:0042625(ATPase coupled ion transmembrane transporter activity);GO:0007035(vacuolar acidification);GO:0008286(insulin receptor signaling pathway);GO:0016049(cell growth);GO:0016241(regulation of macroautophagy);GO:0033572(transferrin transport);GO:0090383(phagosome acidification);GO:0046961(proton-transporting ATPase activity, rotational mechanism)","00190(Oxidative phosphorylation);04145(Phagosome);04966(Collecting duct acid secretion);04721(Synaptic vesicle cycle);05323(Rheumatoid arthritis);05110(Vibrio cholerae infection);05120(Epithelial cell signaling in Helicobacter pylori infection)","NA","NA","ATPase H+ transporting V0 subunit e2 [Source:HGNC Symbol;Acc:HGNC:21723]",{"v":0.30582,"d":"0.31"},{"v":1.392491,"d":"1.39"},{"v":0.21962080903934,"d":"0.22"},{"v":-2.18691333892508,"d":"-2.19"},{"v":0.000921601583252869,"d":"0.00"},{"v":0.0200402770652833,"d":"0.02"},"down","yes"]
[19024,0,"chr10","+",22316386,22320306,"ENST00000602574",5,2290,"MSTRG.1613","COMMD3","GO:0006810(transport);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0006811(ion transport);GO:0005515(protein binding);GO:0006814(sodium ion transport);GO:0005576(extracellular region);GO:0043312(neutrophil degranulation);GO:1904813(ficolin-1-rich granule lumen)","NA","NA","NA","COMM domain containing 3 [Source:HGNC Symbol;Acc:HGNC:23332]",{"v":0.350544,"d":"0.35"},{"v":1.57416,"d":"1.57"},{"v":0.222686385119683,"d":"0.22"},{"v":-2.16691473936945,"d":"-2.17"},{"v":0.000933243480747401,"d":"0.00"},{"v":0.0202711547717119,"d":"0.02"},"down","yes"]
[74124,"j","chr16","+",66604243,66613880,"MSTRG.5989.5",6,2074,"MSTRG.5989","CMTM3","NA","NA","NA","NA","NA",{"v":15.287124,"d":"15.29"},{"v":2.745975,"d":"2.75"},{"v":5.56710239532407,"d":"5.57"},{"v":2.47692661883653,"d":"2.48"},{"v":0.000938384273044051,"d":"0.00"},{"v":0.0203604692927584,"d":"0.02"},"up","yes"]
[166237,0,"chr6","+",43477573,43506553,"ENST00000372452",10,2665,"ENSG00000137221","TJAP1","GO:0005923(bicellular tight junction);GO:0005794(Golgi apparatus);GO:0030054(cell junction);GO:0005515(protein binding);GO:0007030(Golgi organization);GO:0005737(cytoplasm);GO:0005768(endosome);GO:0005802(trans-Golgi network);GO:0005886(plasma membrane)","04530(Tight junction)","K06105","NA","tight junction associated protein 1 [Source:HGNC Symbol;Acc:HGNC:17949]",{"v":3.07286,"d":"3.07"},{"v":0.531399,"d":"0.53"},{"v":5.78258521374711,"d":"5.78"},{"v":2.53171462096428,"d":"2.53"},{"v":0.000944742593443824,"d":"0.00"},{"v":0.0204759763845196,"d":"0.02"},"up","yes"]
[65432,0,"chr15","-",78923059,78937233,"ENST00000534533",9,836,"MSTRG.5350","CTSH","GO:0043231(intracellular membrane-bounded organelle);GO:0005829(cytosol);GO:0016787(hydrolase activity);GO:0008233(peptidase activity);GO:0008234(cysteine-type peptidase activity);GO:0006508(proteolysis);GO:0005615(extracellular space);GO:0000932(P-body);GO:0005764(lysosome);GO:0004177(aminopeptidase activity);GO:0002250(adaptive immune response);GO:0005576(extracellular region);GO:0004252(serine-type endopeptidase activity);GO:0005515(protein binding);GO:0070062(extracellular exosome);GO:0031648(protein destabilization);GO:0010628(positive regulation of gene expression);GO:0044267(cellular protein metabolic process);GO:0030335(positive regulation of cell migration);GO:0043312(neutrophil degranulation);GO:0008284(positive regulation of cell proliferation);GO:0043066(negative regulation of apoptotic process);GO:0070371(ERK1 and ERK2 cascade);GO:0034774(secretory granule lumen);GO:1904813(ficolin-1-rich granule lumen);GO:1904724(tertiary granule lumen);GO:0045766(positive regulation of angiogenesis);GO:0004175(endopeptidase activity);GO:0008656(cysteine-type endopeptidase activator activity involved in apoptotic process);GO:0001656(metanephros development);GO:0010634(positive regulation of epithelial cell migration);GO:0051603(proteolysis involved in cellular protein catabolic process);GO:0004197(cysteine-type endopeptidase activity);GO:0032526(response to retinoic acid);GO:0033619(membrane protein proteolysis);GO:0043129(surfactant homeostasis);GO:0097208(alveolar lamellar body);GO:0097486(multivesicular body lumen);GO:0031638(zymogen activation);GO:0006915(apoptotic process);GO:0019882(antigen processing and presentation);GO:0097067(cellular response to thyroid hormone stimulus);GO:0016505(peptidase activator activity involved in apoptotic process);GO:0030108(HLA-A specific activating MHC class I receptor activity);GO:0070324(thyroid hormone binding);GO:0001913(T cell mediated cytotoxicity);GO:0002764(immune response-regulating signaling pathway);GO:0006919(activation of cysteine-type endopeptidase activity involved in apoptotic process);GO:0010813(neuropeptide catabolic process);GO:0010815(bradykinin catabolic process);GO:0010952(positive regulation of peptidase activity);GO:0060448(dichotomous subdivision of terminal units involved in lung branching);GO:2001235(positive regulation of apoptotic signaling pathway)","04142(Lysosome);04210(Apoptosis)","NA","NA","cathepsin H [Source:HGNC Symbol;Acc:HGNC:2535]",{"v":0.971662,"d":"0.97"},{"v":4.370784,"d":"4.37"},{"v":0.222308400506637,"d":"0.22"},{"v":-2.16936562947216,"d":"-2.17"},{"v":0.000950246070737548,"d":"0.00"},{"v":0.0205627946109405,"d":"0.02"},"down","yes"]
[164447,0,"chr6","-",31580555,31582425,"ENST00000429299",4,897,"MSTRG.12863","LTB","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0006955(immune response);GO:0005125(cytokine activity);GO:0005615(extracellular space);GO:0005164(tumor necrosis factor receptor binding);GO:0005886(plasma membrane);GO:0005575(cellular_component);GO:0033209(tumor necrosis factor-mediated signaling pathway);GO:0007165(signal transduction);GO:0007267(cell-cell signaling);GO:0045084(positive regulation of interleukin-12 biosynthetic process);GO:0005102(receptor binding);GO:0010467(gene expression);GO:0043588(skin development);GO:0048535(lymph node development)","04064(NF-kappa B signaling pathway);04060(Cytokine-cytokine receptor interaction);05323(Rheumatoid arthritis)","K03157","NA","lymphotoxin beta [Source:HGNC Symbol;Acc:HGNC:6711]",{"v":19.404116,"d":"19.40"},{"v":81.118347,"d":"81.12"},{"v":0.239207487795578,"d":"0.24"},{"v":-2.06366554466375,"d":"-2.06"},{"v":0.000950826615575631,"d":"0.00"},{"v":0.0205627946109405,"d":"0.02"},"down","yes"]
[37263,"j","chr12","+",752576,912051,"MSTRG.3007.3",25,10573,"MSTRG.3007","WNK1","NA","NA","NA","NA","NA",{"v":2.845043,"d":"2.85"},{"v":0.512599,"d":"0.51"},{"v":5.55023127239811,"d":"5.55"},{"v":2.47254788832585,"d":"2.47"},{"v":0.000958375562567347,"d":"0.00"},{"v":0.0207034231791295,"d":"0.02"},"up","yes"]
[74959,0,"chr16","-",69118010,69132570,"ENST00000448552",4,2903,"MSTRG.6073","CHTF8","GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0070062(extracellular exosome);GO:0007064(mitotic sister chromatid cohesion);GO:0031390(Ctf18 RFC-like complex);GO:0003677(DNA binding);GO:0007049(cell cycle);GO:0006260(DNA replication);GO:0043142(single-stranded DNA-dependent ATPase activity);GO:0003689(DNA clamp loader activity);GO:1900264(positive regulation of DNA-directed DNA polymerase activity)","NA","NA","NA","chromosome transmission fidelity factor 8 [Source:HGNC Symbol;Acc:HGNC:24353]",{"v":11.774014,"d":"11.77"},{"v":2.122209,"d":"2.12"},{"v":5.54799927811069,"d":"5.55"},{"v":2.4719675999423,"d":"2.47"},{"v":0.000959815273360336,"d":"0.00"},{"v":0.0207119134452065,"d":"0.02"},"up","yes"]
[47428,0,"chr12","+",120446438,120463749,"ENST00000551765",4,4244,"MSTRG.3778","GATC","GO:0006412(translation);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0005739(mitochondrion);GO:0016874(ligase activity);GO:0005515(protein binding);GO:0032543(mitochondrial translation);GO:0050567(glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity);GO:0070681(glutaminyl-tRNAGln biosynthesis via transamidation);GO:0030956(glutamyl-tRNA(Gln) amidotransferase complex);GO:0006450(regulation of translational fidelity)","00970(Aminoacyl-tRNA biosynthesis)","K02435","EC:6.3.5.6;EC:6.3.5.7","glutamyl-tRNA amidotransferase subunit C [Source:HGNC Symbol;Acc:HGNC:25068]",{"v":3.249333,"d":"3.25"},{"v":0.577475,"d":"0.58"},{"v":5.6267942335166,"d":"5.63"},{"v":2.49231320638232,"d":"2.49"},{"v":0.000960869350994448,"d":"0.00"},{"v":0.0207120726769914,"d":"0.02"},"up","yes"]
[136730,0,"chr3","+",50350695,50354079,"ENST00000425346",4,1319,"MSTRG.10960","CYB561D2","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0046872(metal ion binding);GO:0055114(oxidation-reduction process)","NA","NA","NA","cytochrome b561 family member D2 [Source:HGNC Symbol;Acc:HGNC:30253]",{"v":1.162646,"d":"1.16"},{"v":5.039591,"d":"5.04"},{"v":0.230702451845795,"d":"0.23"},{"v":-2.11589475819645,"d":"-2.12"},{"v":0.00096420043971007,"d":"0.00"},{"v":0.0207612603927996,"d":"0.02"},"down","yes"]
[164689,0,"chr6","-",31797396,31806984,"ENST00000375661",5,876,"MSTRG.12882","LSM2","GO:0003723(RNA binding);GO:0006397(mRNA processing);GO:0008380(RNA splicing);GO:0005634(nucleus);GO:0030529(intracellular ribonucleoprotein complex);GO:0005515(protein binding);GO:0005681(spliceosomal complex);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0000398(mRNA splicing, via spliceosome);GO:0000932(P-body);GO:0046540(U4/U6 x U5 tri-snRNP complex);GO:0017160(Ral GTPase binding);GO:0043928(exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay);GO:1990726(Lsm1-7-Pat1 complex);GO:0071013(catalytic step 2 spliceosome);GO:0071011(precatalytic spliceosome);GO:0017070(U6 snRNA binding);GO:0005688(U6 snRNP)","03040(Spliceosome);03018(RNA degradation)","K12621","NA","LSM2 homolog, U6 small nuclear RNA and mRNA degradation associated [Source:HGNC Symbol;Acc:HGNC:13940]",{"v":3.226088,"d":"3.23"},{"v":13.75933,"d":"13.76"},{"v":0.234465486328186,"d":"0.23"},{"v":-2.09255252339519,"d":"-2.09"},{"v":0.000966036241383876,"d":"0.00"},{"v":0.0207781795048958,"d":"0.02"},"down","yes"]
[179521,0,"chr7","+",142618849,142619532,"ENST00000390393",2,552,"MSTRG.14099","TRBV19","NA","NA","NA","NA","T-cell receptor beta variable 19 [Source:HGNC Symbol;Acc:HGNC:12194]",{"v":2.129381,"d":"2.13"},{"v":9.426707,"d":"9.43"},{"v":0.225888107055836,"d":"0.23"},{"v":-2.14631977963772,"d":"-2.15"},{"v":0.000971538597129253,"d":"0.00"},{"v":0.0208738390445099,"d":"0.02"},"down","yes"]
[12967,"j","chr1","-",161541734,161631962,"MSTRG.1160.1",7,2167,"MSTRG.1160","FCGR3B","NA","NA","NA","NA","NA",{"v":12.539867,"d":"12.54"},{"v":2.259526,"d":"2.26"},{"v":5.54977769673816,"d":"5.55"},{"v":2.47242998367235,"d":"2.47"},{"v":0.000973038407388732,"d":"0.00"},{"v":0.0208778368557112,"d":"0.02"},"up","yes"]
[76667,0,"chr16","+",87959871,88077315,"ENST00000538234",13,2372,"MSTRG.6224","BANP","GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0016569(covalent chromatin modification);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0007049(cell cycle);GO:0016604(nuclear body);GO:0007275(multicellular organism development);GO:1901796(regulation of signal transduction by p53 class mediator);GO:0002039(p53 binding);GO:0034504(protein localization to nucleus);GO:0042177(negative regulation of protein catabolic process);GO:0045893(positive regulation of transcription, DNA-templated)","NA","NA","NA","BTG3 associated nuclear protein [Source:HGNC Symbol;Acc:HGNC:13450]",{"v":0.421729,"d":"0.42"},{"v":1.853298,"d":"1.85"},{"v":0.227555957002058,"d":"0.23"},{"v":-2.13570674094849,"d":"-2.14"},{"v":0.000973834819982891,"d":"0.00"},{"v":0.0208778368557112,"d":"0.02"},"down","yes"]
[187962,"j","chr8","-",143574785,143597679,"MSTRG.14619.1",20,4328,"MSTRG.14619","NAPRT","NA","NA","NA","NA","NA",{"v":1.024337,"d":"1.02"},{"v":4.313728,"d":"4.31"},{"v":0.23745980275066,"d":"0.24"},{"v":-2.0742447805195,"d":"-2.07"},{"v":9.841824650624251E-4,"d":"0.00"},{"v":0.0210624180137037,"d":"0.02"},"down","yes"]
[193029,0,"chr9","+",121075012,121177608,"ENST00000373855",44,7660,"ENSG00000119397","CNTRL","GO:0051301(cell division);GO:0000278(mitotic cell cycle);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005829(cytosol);GO:0018108(peptidyl-tyrosine phosphorylation);GO:0005813(centrosome);GO:0005856(cytoskeleton);GO:0007049(cell cycle);GO:0005815(microtubule organizing center);GO:0030496(midbody);GO:0005515(protein binding);GO:0000086(G2/M transition of mitotic cell cycle);GO:0010389(regulation of G2/M transition of mitotic cell cycle);GO:0097711(ciliary basal body docking);GO:0004713(protein tyrosine kinase activity)","NA","NA","NA","centriolin [Source:HGNC Symbol;Acc:HGNC:1858]",{"v":5.427903,"d":"5.43"},{"v":0.983432,"d":"0.98"},{"v":5.51934755021191,"d":"5.52"},{"v":2.46449773408553,"d":"2.46"},{"v":0.000984573310222149,"d":"0.00"},{"v":0.0210624180137037,"d":"0.02"},"up","yes"]
[134247,0,"chr3","-",27376606,27484347,"ENST00000455077",25,3775,"ENSG00000033867","SLC4A7","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005215(transporter activity);GO:0006811(ion transport);GO:0008509(anion transmembrane transporter activity);GO:0006820(anion transport);GO:0098656(anion transmembrane transport);GO:0005452(inorganic anion exchanger activity);GO:0015698(inorganic anion transport);GO:0015293(symporter activity);GO:0055085(transmembrane transport);GO:0005886(plasma membrane);GO:0042995(cell projection);GO:0006814(sodium ion transport);GO:0035725(sodium ion transmembrane transport);GO:0005887(integral component of plasma membrane);GO:0016323(basolateral plasma membrane);GO:0032420(stereocilium);GO:0016324(apical plasma membrane);GO:0051453(regulation of intracellular pH);GO:0015701(bicarbonate transport);GO:0008510(sodium:bicarbonate symporter activity);GO:0060117(auditory receptor cell development);GO:0031410(cytoplasmic vesicle);GO:0045202(synapse)","NA","NA","NA","solute carrier family 4 member 7 [Source:HGNC Symbol;Acc:HGNC:11033]",{"v":0.45419,"d":"0.45"},{"v":1.951367,"d":"1.95"},{"v":0.232754781647942,"d":"0.23"},{"v":-2.10311728848283,"d":"-2.10"},{"v":0.000987546787829513,"d":"0.00"},{"v":0.0211032136474842,"d":"0.02"},"down","yes"]
[47775,0,"chr12","-",122207662,122226052,"ENST00000353548",5,1345,"MSTRG.3819","DIABLO","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005739(mitochondrion);GO:0006915(apoptotic process);GO:0005515(protein binding);GO:0006919(activation of cysteine-type endopeptidase activity involved in apoptotic process);GO:0005758(mitochondrial intermembrane space);GO:0005829(cytosol);GO:0043065(positive regulation of apoptotic process);GO:0008625(extrinsic apoptotic signaling pathway via death domain receptors);GO:0009898(cytoplasmic side of plasma membrane);GO:0035631(CD40 receptor complex);GO:0097193(intrinsic apoptotic signaling pathway);GO:0008635(activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c);GO:0008631(intrinsic apoptotic signaling pathway in response to oxidative stress);GO:0051402(neuron apoptotic process);GO:0005737(cytoplasm)","04210(Apoptosis);04215(Apoptosis - multiple species)","K10522","NA","diablo IAP-binding mitochondrial protein [Source:HGNC Symbol;Acc:HGNC:21528]",{"v":0.816384,"d":"0.82"},{"v":3.598505,"d":"3.60"},{"v":0.226867546383846,"d":"0.23"},{"v":-2.14007785000138,"d":"-2.14"},{"v":0.000993867520862005,"d":"0.00"},{"v":0.0211975156445782,"d":"0.02"},"down","yes"]
[102815,"j","chr19","+",45507486,45527019,"MSTRG.8230.6",13,2268,"MSTRG.8230","VASP","NA","NA","NA","NA","NA",{"v":8.89915,"d":"8.90"},{"v":36.93272,"d":"36.93"},{"v":0.240955716232111,"d":"0.24"},{"v":-2.05316006811161,"d":"-2.05"},{"v":0.000994723884393835,"d":"0.00"},{"v":0.0211975156445782,"d":"0.02"},"down","yes"]
[168941,0,"chr6","+",125781161,125931111,"ENST00000368357",17,5521,"ENSG00000111912","NCOA7","GO:0005634(nucleus);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0005515(protein binding);GO:0030374(ligand-dependent nuclear receptor transcription coactivator activity);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0005622(intracellular);GO:0035257(nuclear hormone receptor binding);GO:1900408(negative regulation of cellular response to oxidative stress);GO:1902083(negative regulation of peptidyl-cysteine S-nitrosylation);GO:1903204(negative regulation of oxidative stress-induced neuron death)","NA","NA","NA","nuclear receptor coactivator 7 [Source:HGNC Symbol;Acc:HGNC:21081]",{"v":1.099932,"d":"1.10"},{"v":0.192189,"d":"0.19"},{"v":5.72317874592198,"d":"5.72"},{"v":2.51681666574206,"d":"2.52"},{"v":0.000995173440156315,"d":"0.00"},{"v":0.0211975156445782,"d":"0.02"},"up","yes"]
[150030,"j","chr4","+",108620566,108630479,"MSTRG.11786.1",6,898,"MSTRG.11786","RPL34","NA","NA","NA","NA","NA",{"v":47.440479,"d":"47.44"},{"v":196.564926,"d":"196.56"},{"v":0.241347629841145,"d":"0.24"},{"v":-2.05081543604857,"d":"-2.05"},{"v":0.000998495698716154,"d":"0.00"},{"v":0.0212454117055863,"d":"0.02"},"down","yes"]
[193169,0,"chr9","-",122844556,122898110,"ENST00000373670",20,9248,"MSTRG.14950","RC3H2","GO:0003723(RNA binding);GO:0003729(mRNA binding);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0046872(metal ion binding);GO:0016740(transferase activity);GO:0016567(protein ubiquitination);GO:0003677(DNA binding);GO:0004842(ubiquitin-protein transferase activity);GO:0001782(B cell homeostasis);GO:0009791(post-embryonic development);GO:0010468(regulation of gene expression);GO:0010608(posttranscriptional regulation of gene expression);GO:0035264(multicellular organism growth);GO:0042098(T cell proliferation);GO:0043029(T cell homeostasis);GO:0048286(lung alveolus development);GO:0048535(lymph node development);GO:0048536(spleen development);GO:0060173(limb development);GO:0061470(T follicular helper cell differentiation);GO:1901224(positive regulation of NIK/NF-kappaB signaling);GO:0000932(P-body);GO:0009986(cell surface);GO:0000209(protein polyubiquitination)","NA","NA","NA","ring finger and CCCH-type domains 2 [Source:HGNC Symbol;Acc:HGNC:21461]",{"v":0.804686,"d":"0.80"},{"v":0.141044,"d":"0.14"},{"v":5.70521255778339,"d":"5.71"},{"v":2.51228063767038,"d":"2.51"},{"v":0.00100705903058967,"d":"0.00"},{"v":0.0214046016082796,"d":"0.02"},"up","yes"]
[139033,0,"chr3","+",111979035,111993363,"ENST00000273359",5,2590,"ENSG00000144827","ABHD10","GO:0016787(hydrolase activity);GO:0005739(mitochondrion);GO:0005759(mitochondrial matrix);GO:0005829(cytosol);GO:0052695(cellular glucuronidation);GO:0004553(hydrolase activity, hydrolyzing O-glycosyl compounds);GO:0102390(mycophenolic acid acyl-glucuronide esterase activity);GO:0019391(glucuronoside catabolic process)","NA","NA","NA","abhydrolase domain containing 10 [Source:HGNC Symbol;Acc:HGNC:25656]",{"v":1.020073,"d":"1.02"},{"v":4.314888,"d":"4.31"},{"v":0.23640775844008,"d":"0.24"},{"v":-2.08065071216651,"d":"-2.08"},{"v":1.01052420606398E-3,"d":"0.00"},{"v":0.0214386649871639,"d":"0.02"},"down","yes"]
[58219,0,"chr14","-",95709967,95714196,"ENST00000554012",4,1391,"MSTRG.4646","TCL1A","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005783(endoplasmic reticulum);GO:0005515(protein binding);GO:0042802(identical protein binding);GO:0043231(intracellular membrane-bounded organelle);GO:0019901(protein kinase binding);GO:0043539(protein serine/threonine kinase activator activity);GO:0033138(positive regulation of peptidyl-serine phosphorylation);GO:0071902(positive regulation of protein serine/threonine kinase activity);GO:0043234(protein complex);GO:0071356(cellular response to tumor necrosis factor);GO:0008284(positive regulation of cell proliferation);GO:0043066(negative regulation of apoptotic process);GO:0007275(multicellular organism development);GO:0032461(positive regulation of protein oligomerization);GO:0070207(protein homotrimerization);GO:0010918(positive regulation of mitochondrial membrane potential)","04151(PI3K-Akt signaling pathway)","K10167","NA","T-cell leukemia/lymphoma 1A [Source:HGNC Symbol;Acc:HGNC:11648]",{"v":1.778043,"d":"1.78"},{"v":7.539307,"d":"7.54"},{"v":0.235836397164885,"d":"0.24"},{"v":-2.08414170499598,"d":"-2.08"},{"v":1.01082850379138E-3,"d":"0.00"},{"v":0.0214386649871639,"d":"0.02"},"down","yes"]
[11763,0,"chr1","-",155336055,155562532,"ENST00000392403",28,10979,"ENSG00000116539","ASH1L","GO:0005634(nucleus);GO:0005794(Golgi apparatus);GO:0046872(metal ion binding);GO:0005654(nucleoplasm);GO:0008168(methyltransferase activity);GO:0016740(transferase activity);GO:0032259(methylation);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0016569(covalent chromatin modification);GO:0003677(DNA binding);GO:0005694(chromosome);GO:0030054(cell junction);GO:0003682(chromatin binding);GO:0018024(histone-lysine N-methyltransferase activity);GO:0005923(bicellular tight junction);GO:0070062(extracellular exosome);GO:0007267(cell-cell signaling);GO:0006366(transcription from RNA polymerase II promoter);GO:0006323(DNA packaging);GO:0046975(histone methyltransferase activity (H3-K36 specific));GO:0097676(histone H3-K36 dimethylation);GO:0042800(histone methyltransferase activity (H3-K4 specific));GO:0001501(skeletal system development);GO:0002674(negative regulation of acute inflammatory response);GO:0007338(single fertilization);GO:0009791(post-embryonic development);GO:0010468(regulation of gene expression);GO:0032635(interleukin-6 production);GO:0043124(negative regulation of I-kappaB kinase/NF-kappaB signaling);GO:0043409(negative regulation of MAPK cascade);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0046697(decidualization);GO:0048733(sebaceous gland development);GO:0050728(negative regulation of inflammatory response);GO:0051568(histone H3-K4 methylation);GO:0061038(uterus morphogenesis);GO:0097722(sperm motility);GO:1903699(tarsal gland development);GO:1903709(uterine gland development)","00310(Lysine degradation)","K06101","EC:2.1.1.43","ASH1 like histone lysine methyltransferase [Source:HGNC Symbol;Acc:HGNC:19088]",{"v":6.835885,"d":"6.84"},{"v":1.249233,"d":"1.25"},{"v":5.47206565948866,"d":"5.47"},{"v":2.45208554127103,"d":"2.45"},{"v":1.01327372064744E-3,"d":"0.00"},{"v":0.0214675164712757,"d":"0.02"},"up","yes"]
[114364,0,"chr2","+",130181928,130190727,"ENST00000281871",3,933,"MSTRG.9101","MZT2B","GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0005813(centrosome);GO:0005815(microtubule organizing center);GO:0005737(cytoplasm);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0005819(spindle);GO:0008274(gamma-tubulin ring complex)","NA","NA","NA","mitotic spindle organizing protein 2B [Source:HGNC Symbol;Acc:HGNC:25886]",{"v":14.302365,"d":"14.30"},{"v":2.569395,"d":"2.57"},{"v":5.56643295406117,"d":"5.57"},{"v":2.47675312505203,"d":"2.48"},{"v":0.00101753338312317,"d":"0.00"},{"v":0.0215347065082794,"d":"0.02"},"up","yes"]
[158952,"j","chr5","+",139293963,139330437,"MSTRG.12384.35",15,3973,"MSTRG.12384","MATR3","NA","NA","NA","NA","NA",{"v":2.632449,"d":"2.63"},{"v":0.469238,"d":"0.47"},{"v":5.61005076315218,"d":"5.61"},{"v":2.48801382527552,"d":"2.49"},{"v":1.02073285351668E-3,"d":"0.00"},{"v":0.0215793394288333,"d":"0.02"},"up","yes"]
[103964,0,"chr19","-",49555711,49580558,"ENST00000339093",9,1000,"MSTRG.8321","NOSIP","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0050999(regulation of nitric-oxide synthase activity);GO:0003723(RNA binding);GO:0016740(transferase activity);GO:0007275(multicellular organism development);GO:0061630(ubiquitin protein ligase activity);GO:0005515(protein binding);GO:0005829(cytosol);GO:0016567(protein ubiquitination);GO:0000139(Golgi membrane);GO:0043086(negative regulation of catalytic activity);GO:0051001(negative regulation of nitric-oxide synthase activity);GO:0004842(ubiquitin-protein transferase activity)","NA","NA","NA","nitric oxide synthase interacting protein [Source:HGNC Symbol;Acc:HGNC:17946]",{"v":4.03751,"d":"4.04"},{"v":16.911057,"d":"16.91"},{"v":0.238749712687977,"d":"0.24"},{"v":-2.06642909788088,"d":"-2.07"},{"v":0.00102244098108299,"d":"0.00"},{"v":0.0215923822130952,"d":"0.02"},"down","yes"]
[152550,0,"chr4","+",183444591,183448198,"ENST00000504169",3,2721,"ENSG00000168564","CDKN2AIP","GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0006974(cellular response to DNA damage stimulus);GO:0005515(protein binding);GO:0030307(positive regulation of cell growth);GO:0031647(regulation of protein stability);GO:0005730(nucleolus);GO:0030308(negative regulation of cell growth);GO:0002039(p53 binding);GO:0009967(positive regulation of signal transduction);GO:0001652(granular component)","NA","NA","NA","CDKN2A interacting protein [Source:HGNC Symbol;Acc:HGNC:24325]",{"v":3.13794,"d":"3.14"},{"v":0.553108,"d":"0.55"},{"v":5.67328622981407,"d":"5.67"},{"v":2.50418465299459,"d":"2.50"},{"v":0.00102672560177849,"d":"0.00"},{"v":0.0216597507547898,"d":"0.02"},"up","yes"]
[131925,"j","chr22","-",42618853,42646979,"MSTRG.10552.4",9,1899,"MSTRG.10552","CYB5R3","NA","NA","NA","NA","NA",{"v":1.010383,"d":"1.01"},{"v":4.304092,"d":"4.30"},{"v":0.234749396620704,"d":"0.23"},{"v":-2.09080664518057,"d":"-2.09"},{"v":1.0326684796331E-3,"d":"0.00"},{"v":0.0217579490339938,"d":"0.02"},"down","yes"]
[115650,0,"chr2","-",159768630,159798255,"ENST00000553424",5,3866,"MSTRG.9190","CD302","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0030246(carbohydrate binding);GO:0042995(cell projection);GO:0007165(signal transduction);GO:0004888(transmembrane signaling receptor activity);GO:0005887(integral component of plasma membrane);GO:0030175(filopodium);GO:0005938(cell cortex);GO:0005902(microvillus);GO:0006909(phagocytosis)","NA","NA","NA","CD302 molecule [Source:HGNC Symbol;Acc:HGNC:30843]",{"v":3.937121,"d":"3.94"},{"v":0.707403,"d":"0.71"},{"v":5.56559839299522,"d":"5.57"},{"v":2.47653680925559,"d":"2.48"},{"v":1.03357954780443E-3,"d":"0.00"},{"v":0.0217579490339938,"d":"0.02"},"up","yes"]
[134111,0,"chr3","+",23916804,23920856,"ENST00000611050",4,2363,"MSTRG.10731","RPL15","GO:0005634(nucleus);GO:0003723(RNA binding);GO:0016020(membrane);GO:0006412(translation);GO:0030529(intracellular ribonucleoprotein complex);GO:0005622(intracellular);GO:0003735(structural constituent of ribosome);GO:0005840(ribosome);GO:0005515(protein binding);GO:0045471(response to ethanol);GO:0022625(cytosolic large ribosomal subunit);GO:0031672(A band);GO:0005829(cytosol);GO:0045296(cadherin binding);GO:0070062(extracellular exosome);GO:0002181(cytoplasmic translation);GO:0006413(translational initiation);GO:0006364(rRNA processing);GO:0000184(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay);GO:0019083(viral transcription);GO:0006614(SRP-dependent cotranslational protein targeting to membrane)","03010(Ribosome)","K02877","NA","ribosomal protein L15 [Source:HGNC Symbol;Acc:HGNC:10306]",{"v":1.631174,"d":"1.63"},{"v":6.830531,"d":"6.83"},{"v":0.238806324134976,"d":"0.24"},{"v":-2.06608705193055,"d":"-2.07"},{"v":0.00103505903589125,"d":"0.00"},{"v":0.021760908078789,"d":"0.02"},"down","yes"]
[167710,0,"chr6","+",87590135,87667451,"ENST00000257789",20,2501,"ENSG00000135336","ORC3","GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0016604(nuclear body);GO:0006260(DNA replication);GO:0005664(nuclear origin of replication recognition complex);GO:0000784(nuclear chromosome, telomeric region);GO:0000082(G1/S transition of mitotic cell cycle);GO:0006270(DNA replication initiation);GO:0003688(DNA replication origin binding);GO:0000808(origin recognition complex);GO:0006267(pre-replicative complex assembly involved in nuclear cell cycle DNA replication);GO:0005656(nuclear pre-replicative complex);GO:0031261(DNA replication preinitiation complex);GO:0061351(neural precursor cell proliferation)","04110(Cell cycle)","K02605","NA","origin recognition complex subunit 3 [Source:HGNC Symbol;Acc:HGNC:8489]",{"v":0.536912,"d":"0.54"},{"v":2.311677,"d":"2.31"},{"v":0.232260821905482,"d":"0.23"},{"v":-2.10618227612383,"d":"-2.11"},{"v":1.03591951739535E-3,"d":"0.00"},{"v":0.021760908078789,"d":"0.02"},"down","yes"]
[32824,0,"chr11","-",72754730,72793681,"ENST00000334805",7,1963,"MSTRG.2689","STARD10","GO:0008289(lipid binding);GO:0006810(transport);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0042995(cell projection);GO:0005515(protein binding);GO:0006869(lipid transport);GO:0005829(cytosol);GO:0006656(phosphatidylcholine biosynthetic process);GO:0005902(microvillus);GO:0046581(intercellular canaliculus);GO:0032782(bile acid secretion);GO:0035360(positive regulation of peroxisome proliferator activated receptor signaling pathway)","NA","NA","NA","StAR related lipid transfer domain containing 10 [Source:HGNC Symbol;Acc:HGNC:10666]",{"v":0.984521,"d":"0.98"},{"v":4.184537,"d":"4.18"},{"v":0.235275969599504,"d":"0.24"},{"v":-2.08757411945918,"d":"-2.09"},{"v":1.05071493884658E-3,"d":"0.00"},{"v":0.022048300328628,"d":"0.02"},"down","yes"]
[1393,0,"chr1","+",10210805,10308597,"ENST00000377093",21,7565,"ENSG00000054523","KIF1B","GO:0005737(cytoplasm);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:1904115(axon cytoplasm);GO:0005739(mitochondrion);GO:0003777(microtubule motor activity);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0008017(microtubule binding);GO:0006915(apoptotic process);GO:0005874(microtubule);GO:0030659(cytoplasmic vesicle membrane);GO:0031410(cytoplasmic vesicle);GO:0007018(microtubule-based movement);GO:0005875(microtubule associated complex);GO:0030705(cytoskeleton-dependent intracellular transport);GO:0016887(ATPase activity);GO:0005871(kinesin complex);GO:0043005(neuron projection);GO:0008089(anterograde axonal transport);GO:0019894(kinesin binding);GO:0007270(neuron-neuron synaptic transmission);GO:0007274(neuromuscular synaptic transmission);GO:0019900(kinase binding);GO:0097110(scaffold protein binding);GO:1990939(ATP-dependent microtubule motor activity);GO:0010628(positive regulation of gene expression);GO:0010970(transport along microtubule);GO:0032418(lysosome localization);GO:0047497(mitochondrion transport along microtubule);GO:1904647(response to rotenone);GO:1990090(cellular response to nerve growth factor stimulus);GO:1990778(protein localization to cell periphery);GO:0016020(membrane);GO:0003774(motor activity)","NA","NA","NA","kinesin family member 1B [Source:HGNC Symbol;Acc:HGNC:16636]",{"v":1.634956,"d":"1.63"},{"v":0.292665,"d":"0.29"},{"v":5.58644183622914,"d":"5.59"},{"v":2.48192968205474,"d":"2.48"},{"v":0.00105399421458404,"d":"0.00"},{"v":0.022093683811641,"d":"0.02"},"up","yes"]
[4846,0,"chr1","-",41506365,41918707,"ENST00000372584",8,12319,"ENSG00000127124","HIVEP3","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0007165(signal transduction);GO:0007275(multicellular organism development);GO:0043565(sequence-specific DNA binding);GO:0045893(positive regulation of transcription, DNA-templated);GO:0044212(transcription regulatory region DNA binding);GO:0006366(transcription from RNA polymerase II promoter);GO:0003677(DNA binding);GO:0035914(skeletal muscle cell differentiation)","NA","NA","NA","human immunodeficiency virus type I enhancer binding protein 3 [Source:HGNC Symbol;Acc:HGNC:13561]",{"v":0.865877,"d":"0.87"},{"v":0.154546,"d":"0.15"},{"v":5.60271375512792,"d":"5.60"},{"v":2.486125786588,"d":"2.49"},{"v":0.0010571144791239,"d":"0.00"},{"v":0.0221232578939405,"d":"0.02"},"up","yes"]
[101161,0,"chr19","+",38930999,38933020,"ENST00000402029",3,929,"ENSG00000128626","MRPS12","GO:0003723(RNA binding);GO:0030529(intracellular ribonucleoprotein complex);GO:0005622(intracellular);GO:0003735(structural constituent of ribosome);GO:0006412(translation);GO:0005840(ribosome);GO:0005739(mitochondrion);GO:0015935(small ribosomal subunit);GO:0005515(protein binding);GO:0032543(mitochondrial translation);GO:0005743(mitochondrial inner membrane);GO:0070125(mitochondrial translational elongation);GO:0070126(mitochondrial translational termination);GO:0005761(mitochondrial ribosome);GO:0005763(mitochondrial small ribosomal subunit)","03010(Ribosome)","K02950","NA","mitochondrial ribosomal protein S12 [Source:HGNC Symbol;Acc:HGNC:10380]",{"v":5.007694,"d":"5.01"},{"v":0.869976,"d":"0.87"},{"v":5.75612890470542,"d":"5.76"},{"v":2.52509890064265,"d":"2.53"},{"v":1.05764109397957E-3,"d":"0.00"},{"v":0.0221232578939405,"d":"0.02"},"up","yes"]
[94571,0,"chr19","+",2164149,2232578,"ENST00000398665",28,7436,"MSTRG.7631","DOT1L","GO:0005634(nucleus);GO:0043231(intracellular membrane-bounded organelle);GO:0005654(nucleoplasm);GO:0008168(methyltransferase activity);GO:0016740(transferase activity);GO:0032259(methylation);GO:0016569(covalent chromatin modification);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0018024(histone-lysine N-methyltransferase activity);GO:0051726(regulation of cell cycle);GO:0031151(histone methyltransferase activity (H3-K79 specific));GO:0034729(histone H3-K79 methylation);GO:0043234(protein complex);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0006281(DNA repair);GO:0042054(histone methyltransferase activity);GO:0008284(positive regulation of cell proliferation);GO:0032200(telomere organization);GO:0000077(DNA damage checkpoint);GO:0000781(chromosome, telomeric region);GO:0006342(chromatin silencing);GO:0006348(chromatin silencing at telomere);GO:0046425(regulation of JAK-STAT cascade);GO:2000677(regulation of transcription regulatory region DNA binding)","00310(Lysine degradation);05202(Transcriptional misregulation in cancers)","K11427","EC:2.1.1.43","DOT1 like histone lysine methyltransferase [Source:HGNC Symbol;Acc:HGNC:24948]",{"v":2.511101,"d":"2.51"},{"v":0.455882,"d":"0.46"},{"v":5.50822581281998,"d":"5.51"},{"v":2.46158770478111,"d":"2.46"},{"v":1.06261937751888E-3,"d":"0.00"},{"v":0.0222024020132217,"d":"0.02"},"up","yes"]
[192789,0,"chr9","+",113536504,113597737,"ENST00000462143",7,2759,"MSTRG.14923","RGS3","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0005886(plasma membrane);GO:0043547(positive regulation of GTPase activity);GO:0005515(protein binding);GO:0009968(negative regulation of signal transduction);GO:0005096(GTPase activator activity);GO:0008277(regulation of G-protein coupled receptor protein signaling pathway);GO:0000188(inactivation of MAPK activity)","04360(Axon guidance)","K07524","NA","regulator of G protein signaling 3 [Source:HGNC Symbol;Acc:HGNC:9999]",{"v":0.469574,"d":"0.47"},{"v":2.023548,"d":"2.02"},{"v":0.232054786938585,"d":"0.23"},{"v":-2.10746263645995,"d":"-2.11"},{"v":0.00106366874411432,"d":"0.00"},{"v":0.0222024020132217,"d":"0.02"},"down","yes"]
[187794,0,"chr8","+",142727203,142736927,"ENST00000336138",2,2259,"ENSG00000130193","THEM6","GO:0005576(extracellular region)","NA","NA","NA","thioesterase superfamily member 6 [Source:HGNC Symbol;Acc:HGNC:29656]",{"v":2.517502,"d":"2.52"},{"v":0.437962,"d":"0.44"},{"v":5.74822016521981,"d":"5.75"},{"v":2.52311532017866,"d":"2.52"},{"v":1.06631323010787E-3,"d":"0.00"},{"v":0.0222341477316907,"d":"0.02"},"up","yes"]
[53003,0,"chr14","-",22900777,22919178,"ENST00000346528",12,2361,"MSTRG.4266","RBM23","GO:0005634(nucleus);GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0016020(membrane);GO:0005515(protein binding);GO:0006397(mRNA processing)","NA","NA","NA","RNA binding motif protein 23 [Source:HGNC Symbol;Acc:HGNC:20155]",{"v":1.995327,"d":"2.00"},{"v":0.345938,"d":"0.35"},{"v":5.76787459024449,"d":"5.77"},{"v":2.52803979668704,"d":"2.53"},{"v":0.00107284973243099,"d":"0.00"},{"v":0.0223334866834946,"d":"0.02"},"up","yes"]
[163275,0,"chr6","-",24839359,24877355,"ENST00000378023",14,2442,"MSTRG.12716","RIPOR2","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0007155(cell adhesion);GO:0007605(sensory perception of sound);GO:0048741(skeletal muscle fiber development);GO:0005886(plasma membrane);GO:0005856(cytoskeleton);GO:0042995(cell projection);GO:0005515(protein binding);GO:0007275(multicellular organism development);GO:0030154(cell differentiation);GO:0006935(chemotaxis);GO:2000114(regulation of establishment of cell polarity);GO:0030175(filopodium);GO:0032420(stereocilium);GO:0007517(muscle organ development);GO:0060171(stereocilium membrane);GO:0016324(apical plasma membrane);GO:0051491(positive regulation of filopodium assembly);GO:0007162(negative regulation of cell adhesion);GO:0009968(negative regulation of signal transduction);GO:1901741(positive regulation of myoblast fusion);GO:0071889(14-3-3 protein binding);GO:2000405(negative regulation of T cell migration);GO:0090023(positive regulation of neutrophil chemotaxis);GO:0045663(positive regulation of myoblast differentiation);GO:1990869(cellular response to chemokine);GO:0035024(negative regulation of Rho protein signal transduction);GO:1903904(negative regulation of establishment of T cell polarity);GO:1905872(negative regulation of protein localization to cell leading edge);GO:2000391(positive regulation of neutrophil extravasation);GO:2001107(negative regulation of Rho guanyl-nucleotide exchange factor activity)","NA","NA","NA","RHO family interacting cell polarization regulator 2 [Source:HGNC Symbol;Acc:HGNC:13872]",{"v":6.464918,"d":"6.46"},{"v":1.173733,"d":"1.17"},{"v":5.5079971339308,"d":"5.51"},{"v":2.46152780877119,"d":"2.46"},{"v":0.00107333463897328,"d":"0.00"},{"v":0.0223334866834946,"d":"0.02"},"up","yes"]
[123323,0,"chr20","-",35650326,35664900,"ENST00000374104",3,5213,"MSTRG.9710","RBM12","GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005515(protein binding)","NA","NA","NA","RNA binding motif protein 12 [Source:HGNC Symbol;Acc:HGNC:9898]",{"v":0.458454,"d":"0.46"},{"v":1.929245,"d":"1.93"},{"v":0.237633893051427,"d":"0.24"},{"v":-2.0731874765517,"d":"-2.07"},{"v":0.00107473097189664,"d":"0.00"},{"v":0.0223390509158516,"d":"0.02"},"down","yes"]
[90946,0,"chr18","+",12991362,13125036,"ENST00000506447",45,7960,"MSTRG.7442","CEP192","GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005813(centrosome);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0005814(centriole);GO:0019902(phosphatase binding);GO:0000086(G2/M transition of mitotic cell cycle);GO:0010389(regulation of G2/M transition of mitotic cell cycle);GO:0010923(negative regulation of phosphatase activity);GO:0097711(ciliary basal body docking);GO:0051225(spindle assembly);GO:0051298(centrosome duplication);GO:0000242(pericentriolar material)","NA","NA","NA","centrosomal protein 192 [Source:HGNC Symbol;Acc:HGNC:25515]",{"v":1.629366,"d":"1.63"},{"v":0.294816,"d":"0.29"},{"v":5.52672175187235,"d":"5.53"},{"v":2.46642398050958,"d":"2.47"},{"v":1.07863631159809E-3,"d":"0.00"},{"v":0.0223967002454385,"d":"0.02"},"up","yes"]
[138927,0,"chr3","+",108822698,108855005,"ENST00000295756",6,1919,"MSTRG.11100","TRAT1","GO:0005622(intracellular);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005886(plasma membrane);GO:0002376(immune system process);GO:0002250(adaptive immune response);GO:0046854(phosphatidylinositol phosphorylation);GO:0050852(T cell receptor signaling pathway);GO:0005887(integral component of plasma membrane);GO:0007165(signal transduction);GO:0046934(phosphatidylinositol-4,5-bisphosphate 3-kinase activity);GO:0014066(regulation of phosphatidylinositol 3-kinase signaling);GO:0038111(interleukin-7-mediated signaling pathway);GO:0048015(phosphatidylinositol-mediated signaling);GO:0006968(cellular defense response);GO:0042101(T cell receptor complex);GO:0005068(transmembrane receptor protein tyrosine kinase adaptor activity);GO:0001920(negative regulation of receptor recycling);GO:0007169(transmembrane receptor protein tyrosine kinase signaling pathway);GO:0050850(positive regulation of calcium-mediated signaling);GO:0050862(positive regulation of T cell receptor signaling pathway);GO:0051051(negative regulation of transport)","NA","NA","NA","T-cell receptor associated transmembrane adaptor 1 [Source:HGNC Symbol;Acc:HGNC:30698]",{"v":6.319034,"d":"6.32"},{"v":26.007366,"d":"26.01"},{"v":0.242970933696246,"d":"0.24"},{"v":-2.04114435850662,"d":"-2.04"},{"v":1.08113171206156E-3,"d":"0.00"},{"v":0.0224113680826132,"d":"0.02"},"down","yes"]
[30357,0,"chr11","-",62789971,62792021,"ENST00000307366",2,1288,"MSTRG.2476","TMEM223","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005739(mitochondrion);GO:0007399(nervous system development)","NA","NA","NA","transmembrane protein 223 [Source:HGNC Symbol;Acc:HGNC:28464]",{"v":1.359624,"d":"1.36"},{"v":5.771306,"d":"5.77"},{"v":0.235583419073603,"d":"0.24"},{"v":-2.08569009248504,"d":"-2.09"},{"v":0.00108160786936,"d":"0.00"},{"v":0.0224113680826132,"d":"0.02"},"down","yes"]
[154805,0,"chr5","+",54517763,54546585,"ENST00000381410",2,5218,"MSTRG.12049","SNX18","GO:0006810(transport);GO:0016020(membrane);GO:0015031(protein transport);GO:0051301(cell division);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0007049(cell cycle);GO:0030659(cytoplasmic vesicle membrane);GO:0031410(cytoplasmic vesicle);GO:0035091(phosphatidylinositol binding);GO:0008289(lipid binding);GO:0000278(mitotic cell cycle);GO:0005768(endosome);GO:0006897(endocytosis);GO:0031234(extrinsic component of cytoplasmic side of plasma membrane);GO:0070062(extracellular exosome);GO:0043547(positive regulation of GTPase activity);GO:0012505(endomembrane system);GO:0010008(endosome membrane);GO:0016197(endosomal transport);GO:0030136(clathrin-coated vesicle);GO:0000281(mitotic cytokinesis);GO:0036089(cleavage furrow formation);GO:0005546(phosphatidylinositol-4,5-bisphosphate binding)","NA","NA","NA","sorting nexin 18 [Source:HGNC Symbol;Acc:HGNC:19245]",{"v":1.413646,"d":"1.41"},{"v":5.841423,"d":"5.84"},{"v":0.242003703549632,"d":"0.24"},{"v":-2.04689896866104,"d":"-2.05"},{"v":1.08397342745022E-3,"d":"0.00"},{"v":0.0224368893121182,"d":"0.02"},"down","yes"]
[116379,0,"chr2","+",171922448,171983682,"ENST00000412731",10,1567,"MSTRG.9234","HAT1","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0043231(intracellular membrane-bounded organelle);GO:0005654(nucleoplasm);GO:0016740(transferase activity);GO:0016746(transferase activity, transferring acyl groups);GO:0000790(nuclear chromatin);GO:0005515(protein binding);GO:0004402(histone acetyltransferase activity);GO:0006325(chromatin organization);GO:0016573(histone acetylation);GO:0043234(protein complex);GO:0000784(nuclear chromosome, telomeric region);GO:0043967(histone H4 acetylation);GO:0016363(nuclear matrix);GO:0010485(H4 histone acetyltransferase activity);GO:0042393(histone binding);GO:0006323(DNA packaging);GO:0006335(DNA replication-dependent nucleosome assembly);GO:0006336(DNA replication-independent nucleosome assembly);GO:0006348(chromatin silencing at telomere);GO:0006475(internal protein amino acid acetylation);GO:0007584(response to nutrient)","05034(Alcoholism)","K11303","EC:2.3.1.48","histone acetyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:4821]",{"v":0.750648,"d":"0.75"},{"v":3.263318,"d":"3.26"},{"v":0.230026004207987,"d":"0.23"},{"v":-2.12013112927752,"d":"-2.12"},{"v":0.00108582261581936,"d":"0.00"},{"v":0.022451680169105,"d":"0.02"},"down","yes"]
[171534,"j","chr7","-",5313035,5397326,"MSTRG.13468.3",26,7874,"MSTRG.13468","TNRC18","NA","NA","NA","NA","NA",{"v":9.963111,"d":"9.96"},{"v":1.841681,"d":"1.84"},{"v":5.40979192379136,"d":"5.41"},{"v":2.43557310490471,"d":"2.44"},{"v":0.00109409831255404,"d":"0.00"},{"v":0.0225991830989763,"d":"0.02"},"up","yes"]
[176418,0,"chr7","+",98281675,98291524,"ENST00000297290",3,780,"MSTRG.13783","BRI3","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005886(plasma membrane);GO:0043312(neutrophil degranulation);GO:0035577(azurophil granule membrane);GO:0042802(identical protein binding)","NA","NA","NA","brain protein I3 [Source:HGNC Symbol;Acc:HGNC:1109]",{"v":1.030838,"d":"1.03"},{"v":4.517004,"d":"4.52"},{"v":0.228212771119972,"d":"0.23"},{"v":-2.13154856568013,"d":"-2.13"},{"v":1.09529776710954E-3,"d":"0.00"},{"v":0.0226003672737889,"d":"0.02"},"down","yes"]
[11194,0,"chr1","+",153728067,153774808,"ENST00000318967",30,5235,"MSTRG.986","INTS3","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005730(nucleolus);GO:0005515(protein binding);GO:0006281(DNA repair);GO:0006974(cellular response to DNA damage stimulus);GO:0005654(nucleoplasm);GO:0042795(snRNA transcription from RNA polymerase II promoter);GO:0007093(mitotic cell cycle checkpoint);GO:0010212(response to ionizing radiation);GO:0032039(integrator complex);GO:0016180(snRNA processing);GO:0070876(SOSS complex)","NA","NA","NA","integrator complex subunit 3 [Source:HGNC Symbol;Acc:HGNC:26153]",{"v":3.773373,"d":"3.77"},{"v":0.688413,"d":"0.69"},{"v":5.48126342762266,"d":"5.48"},{"v":2.45450847177692,"d":"2.45"},{"v":0.00109778181434018,"d":"0.00"},{"v":0.02260951605934,"d":"0.02"},"up","yes"]
[2677,0,"chr1","+",23692306,23696418,"ENST00000482370",5,879,"MSTRG.232","RPL11","GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0006412(translation);GO:0030529(intracellular ribonucleoprotein complex);GO:0005622(intracellular);GO:0003735(structural constituent of ribosome);GO:0005840(ribosome);GO:0005515(protein binding);GO:0005654(nucleoplasm);GO:0005730(nucleolus);GO:0006364(rRNA processing);GO:0000027(ribosomal large subunit assembly);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0031012(extracellular matrix);GO:0019843(rRNA binding);GO:0042273(ribosomal large subunit biogenesis);GO:0032435(negative regulation of proteasomal ubiquitin-dependent protein catabolic process);GO:0006605(protein targeting);GO:0043234(protein complex);GO:0006413(translational initiation);GO:0034504(protein localization to nucleus);GO:0000184(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay);GO:0019083(viral transcription);GO:0006614(SRP-dependent cotranslational protein targeting to membrane);GO:0010628(positive regulation of gene expression);GO:0050821(protein stabilization);GO:0022625(cytosolic large ribosomal subunit);GO:0031625(ubiquitin protein ligase binding);GO:1901796(regulation of signal transduction by p53 class mediator);GO:0008097(5S rRNA binding);GO:1990948(ubiquitin ligase inhibitor activity);GO:1904667(negative regulation of ubiquitin protein ligase activity);GO:2000059(negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process);GO:2000435(negative regulation of protein neddylation);GO:0032092(positive regulation of protein binding);GO:1901798(positive regulation of signal transduction by p53 class mediator);GO:1902255(positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator)","03010(Ribosome)","NA","NA","ribosomal protein L11 [Source:HGNC Symbol;Acc:HGNC:10301]",{"v":34.823532,"d":"34.82"},{"v":142.384628,"d":"142.38"},{"v":0.244573676871916,"d":"0.24"},{"v":-2.03165895794741,"d":"-2.03"},{"v":1.09802632570375E-3,"d":"0.00"},{"v":0.02260951605934,"d":"0.02"},"down","yes"]
[158216,0,"chr5","-",132488671,132490754,"ENST00000493208",2,1023,"MSTRG.12289","IRF1","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0006915(apoptotic process);GO:0005515(protein binding);GO:0008285(negative regulation of cell proliferation);GO:0045893(positive regulation of transcription, DNA-templated);GO:0002376(immune system process);GO:0045087(innate immune response);GO:0000975(regulatory region DNA binding);GO:0051607(defense response to virus);GO:0050776(regulation of immune response);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0007050(cell cycle arrest);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0071260(cellular response to mechanical stimulus);GO:0045892(negative regulation of transcription, DNA-templated);GO:0000790(nuclear chromatin);GO:0006366(transcription from RNA polymerase II promoter);GO:0051726(regulation of cell cycle);GO:0032728(positive regulation of interferon-beta production);GO:0060333(interferon-gamma-mediated signaling pathway);GO:0001077(transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0060337(type I interferon signaling pathway);GO:0007596(blood coagulation);GO:0035458(cellular response to interferon-beta);GO:0045088(regulation of innate immune response);GO:0043565(sequence-specific DNA binding);GO:0002819(regulation of adaptive immune response);GO:0010468(regulation of gene expression);GO:0032481(positive regulation of type I interferon production);GO:0034124(regulation of MyD88-dependent toll-like receptor signaling pathway);GO:0043374(CD8-positive, alpha-beta T cell differentiation);GO:0045084(positive regulation of interleukin-12 biosynthetic process);GO:0045590(negative regulation of regulatory T cell differentiation);GO:2000564(regulation of CD8-positive, alpha-beta T cell proliferation)","04917(Prolactin signaling pathway);05133(Pertussis);05160(Hepatitis C);05165(Human papillomavirus infection)","NA","NA","interferon regulatory factor 1 [Source:HGNC Symbol;Acc:HGNC:6116]",{"v":4.713175,"d":"4.71"},{"v":0.817119,"d":"0.82"},{"v":5.76803990606019,"d":"5.77"},{"v":2.52808114586791,"d":"2.53"},{"v":1.102722847977E-3,"d":"0.00"},{"v":0.022682619247161,"d":"0.02"},"up","yes"]
[171533,0,"chr7","-",5306800,5423546,"ENST00000430969",30,10562,"MSTRG.13468","TNRC18","GO:0005634(nucleus);GO:0005829(cytosol);GO:0005739(mitochondrion);GO:0031965(nuclear membrane);GO:0003682(chromatin binding);GO:0000976(transcription regulatory region sequence-specific DNA binding);GO:0000785(chromatin);GO:0006342(chromatin silencing);GO:0031507(heterochromatin assembly);GO:0005677(chromatin silencing complex)","NA","NA","NA","trinucleotide repeat containing 18 [Source:HGNC Symbol;Acc:HGNC:11962]",{"v":2.54352,"d":"2.54"},{"v":0.467863,"d":"0.47"},{"v":5.43646323817015,"d":"5.44"},{"v":2.44266839262789,"d":"2.44"},{"v":1.10491943350041E-3,"d":"0.00"},{"v":0.0226970176654217,"d":"0.02"},"up","yes"]
[99896,0,"chr19","+",35000323,35026469,"ENST00000600231",18,2534,"MSTRG.8067","GRAMD1A","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005515(protein binding)","NA","NA","NA","GRAM domain containing 1A [Source:HGNC Symbol;Acc:HGNC:29305]",{"v":3.846195,"d":"3.85"},{"v":0.692303,"d":"0.69"},{"v":5.55565265497911,"d":"5.56"},{"v":2.47395640338629,"d":"2.47"},{"v":0.00110600020550735,"d":"0.00"},{"v":0.0226970176654217,"d":"0.02"},"up","yes"]
[25824,"s","chr11","+",5225461,5234466,"MSTRG.2146.6",4,529,"MSTRG.2146","HBB","NA","NA","NA","NA","NA",{"v":29.058519,"d":"29.06"},{"v":118.898392,"d":"118.90"},{"v":0.244397914145046,"d":"0.24"},{"v":-2.03269612260077,"d":"-2.03"},{"v":0.00110686385926481,"d":"0.00"},{"v":0.0226970176654217,"d":"0.02"},"down","yes"]
[95478,0,"chr19","-",6413348,6424794,"ENST00000398148",20,2993,"MSTRG.7727","KHSRP","GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0006397(mRNA processing);GO:0006810(transport);GO:0008380(RNA splicing);GO:0051028(mRNA transport);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005654(nucleoplasm);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0005829(cytosol);GO:0061158(3'-UTR-mediated mRNA destabilization);GO:0043488(regulation of mRNA stability);GO:0061014(positive regulation of mRNA catabolic process);GO:0000375(RNA splicing, via transesterification reactions);GO:0071345(cellular response to cytokine stimulus);GO:0045019(negative regulation of nitric oxide biosynthetic process);GO:0000178(exosome (RNase complex));GO:0035925(mRNA 3'-UTR AU-rich region binding);GO:0010586(miRNA metabolic process);GO:0003729(mRNA binding);GO:0006402(mRNA catabolic process);GO:2000628(regulation of miRNA metabolic process);GO:0010494(cytoplasmic stress granule)","NA","NA","NA","KH-type splicing regulatory protein [Source:HGNC Symbol;Acc:HGNC:6316]",{"v":0.564578,"d":"0.56"},{"v":2.398757,"d":"2.40"},{"v":0.235362731614749,"d":"0.24"},{"v":-2.08704219919752,"d":"-2.09"},{"v":1.10897950892567E-3,"d":"0.00"},{"v":0.0227168597542662,"d":"0.02"},"down","yes"]
[94322,0,"chr19","+",1426349,1435684,"ENST00000585485",5,3943,"MSTRG.7609","DAZAP1","GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0007275(multicellular organism development);GO:0030154(cell differentiation);GO:0007283(spermatogenesis);GO:0035613(RNA stem-loop binding);GO:0001893(maternal placenta development);GO:0008283(cell proliferation);GO:0048026(positive regulation of mRNA splicing, via spliceosome)","03015(mRNA surveillance pathway)","NA","NA","DAZ associated protein 1 [Source:HGNC Symbol;Acc:HGNC:2683]",{"v":2.238596,"d":"2.24"},{"v":0.402167,"d":"0.40"},{"v":5.56633438347751,"d":"5.57"},{"v":2.47672757753308,"d":"2.48"},{"v":0.00111078688953137,"d":"0.00"},{"v":0.0227303526060463,"d":"0.02"},"up","yes"]
[54040,0,"chr14","+",31025466,31096450,"ENST00000542754",6,4243,"MSTRG.4306","AP4S1","GO:0006810(transport);GO:0008565(protein transporter activity);GO:0015031(protein transport);GO:0016020(membrane);GO:0005794(Golgi apparatus);GO:0005905(clathrin-coated pit);GO:0005215(transporter activity);GO:0031904(endosome lumen);GO:0032588(trans-Golgi network membrane)","04142(Lysosome)","K12403","NA","adaptor related protein complex 4 sigma 1 subunit [Source:HGNC Symbol;Acc:HGNC:575]",{"v":0.282468,"d":"0.28"},{"v":1.214848,"d":"1.21"},{"v":0.232513038668212,"d":"0.23"},{"v":-2.10461647417409,"d":"-2.10"},{"v":0.00111540483832754,"d":"0.00"},{"v":0.022801271633084,"d":"0.02"},"down","yes"]
[84984,0,"chr17","+",48048773,48061480,"ENST00000361665",6,4729,"MSTRG.6959","NFE2L1","GO:0005634(nucleus);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005829(cytosol);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005515(protein binding);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0005737(cytoplasm);GO:0034599(cellular response to oxidative stress);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0006954(inflammatory response);GO:0006366(transcription from RNA polymerase II promoter);GO:0045893(positive regulation of transcription, DNA-templated);GO:0009653(anatomical structure morphogenesis);GO:0000976(transcription regulatory region sequence-specific DNA binding);GO:0003712(transcription cofactor activity);GO:0006783(heme biosynthetic process);GO:0000980(RNA polymerase II distal enhancer sequence-specific DNA binding);GO:0001190(transcriptional activator activity, RNA polymerase II transcription factor binding);GO:0001205(transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding);GO:0019904(protein domain specific binding);GO:0032403(protein complex binding);GO:0030218(erythrocyte differentiation);GO:0043234(protein complex)","NA","NA","NA","nuclear factor, erythroid 2 like 1 [Source:HGNC Symbol;Acc:HGNC:7781]",{"v":3.54998,"d":"3.55"},{"v":0.64842,"d":"0.65"},{"v":5.47481570586965,"d":"5.47"},{"v":2.45281040129775,"d":"2.45"},{"v":0.00112253354037743,"d":"0.00"},{"v":0.0229233165087601,"d":"0.02"},"up","yes"]
[47974,0,"chr12","+",122980721,122982873,"ENST00000536502",5,1273,"MSTRG.3844","ARL6IP4","GO:0003723(RNA binding);GO:0006397(mRNA processing);GO:0008380(RNA splicing);GO:0005634(nucleus);GO:0016607(nuclear speck);GO:0005515(protein binding);GO:0005730(nucleolus)","NA","NA","NA","ADP ribosylation factor like GTPase 6 interacting protein 4 [Source:HGNC Symbol;Acc:HGNC:18076]",{"v":0.652472,"d":"0.65"},{"v":2.848688,"d":"2.85"},{"v":0.229042983998248,"d":"0.23"},{"v":-2.12630972371867,"d":"-2.13"},{"v":1.12996421887233E-3,"d":"0.00"},{"v":0.0230512700649955,"d":"0.02"},"down","yes"]
[66346,"j","chr15","+",90002416,90082417,"MSTRG.5407.3",6,4830,"MSTRG.5407","ZNF710","NA","NA","NA","NA","NA",{"v":0.965288,"d":"0.97"},{"v":0.168936,"d":"0.17"},{"v":5.7139271676848,"d":"5.71"},{"v":2.51448264714415,"d":"2.51"},{"v":1.13891321961974E-3,"d":"0.00"},{"v":0.0231924265123554,"d":"0.02"},"up","yes"]
[199034,0,"chrX","-",103252995,103255203,"ENST00000372685",3,1222,"MSTRG.15393","TCEAL8","GO:0005634(nucleus);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0050699(WW domain binding)","NA","NA","NA","transcription elongation factor A like 8 [Source:HGNC Symbol;Acc:HGNC:28683]",{"v":0.999462,"d":"1.00"},{"v":4.301602,"d":"4.30"},{"v":0.232346460690692,"d":"0.23"},{"v":-2.10565042629385,"d":"-2.11"},{"v":0.00113922774257173,"d":"0.00"},{"v":0.0231924265123554,"d":"0.02"},"down","yes"]
[42900,"j","chr12","+",56116599,56117844,"MSTRG.3447.3",3,718,"MSTRG.3447","RPL41","NA","NA","NA","NA","NA",{"v":15.596804,"d":"15.60"},{"v":63.622639,"d":"63.62"},{"v":0.245145505517305,"d":"0.25"},{"v":-2.02828978330388,"d":"-2.03"},{"v":0.00114185674558937,"d":"0.00"},{"v":0.0232220568157477,"d":"0.02"},"down","yes"]
[129218,"j","chr22","+",22712280,22906799,"MSTRG.10249.14",5,979,"MSTRG.10249","IGLV3-21","NA","NA","NA","NA","NA",{"v":2.421344,"d":"2.42"},{"v":10.067934,"d":"10.07"},{"v":0.240500583337157,"d":"0.24"},{"v":-2.05588770161303,"d":"-2.06"},{"v":1.14454605774548E-3,"d":"0.00"},{"v":0.0232387459443155,"d":"0.02"},"down","yes"]
[60757,0,"chr15","-",34233259,34336844,"ENST00000397707",24,4194,"MSTRG.4885","SLC12A6","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005215(transporter activity);GO:0055085(transmembrane transport);GO:0006811(ion transport);GO:0005887(integral component of plasma membrane);GO:0015293(symporter activity);GO:0006813(potassium ion transport);GO:0005886(plasma membrane);GO:0071805(potassium ion transmembrane transport);GO:0015377(cation:chloride symporter activity);GO:0015379(potassium:chloride symporter activity);GO:0071477(cellular hypotonic salinity response);GO:1902476(chloride transmembrane transport);GO:0022820(potassium ion symporter activity);GO:0016323(basolateral plasma membrane);GO:0007268(chemical synaptic transmission);GO:0001525(angiogenesis)","NA","NA","NA","solute carrier family 12 member 6 [Source:HGNC Symbol;Acc:HGNC:10914]",{"v":1.373318,"d":"1.37"},{"v":0.243248,"d":"0.24"},{"v":5.64575248306255,"d":"5.65"},{"v":2.49716588059672,"d":"2.50"},{"v":0.00114540219101439,"d":"0.00"},{"v":0.0232387459443155,"d":"0.02"},"up","yes"]
[101400,0,"chr19","+",39971170,39981408,"ENST00000593455",10,1532,"MSTRG.8139","PSMC4","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0005829(cytosol);GO:0016787(hydrolase activity);GO:0005515(protein binding);GO:0000502(proteasome complex);GO:0038095(Fc-epsilon receptor signaling pathway);GO:0030163(protein catabolic process);GO:0036402(proteasome-activating ATPase activity);GO:1901800(positive regulation of proteasomal protein catabolic process);GO:0005654(nucleoplasm);GO:0000165(MAPK cascade);GO:0000209(protein polyubiquitination);GO:0002223(stimulatory C-type lectin receptor signaling pathway);GO:0002479(antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent);GO:0006521(regulation of cellular amino acid metabolic process);GO:0010972(negative regulation of G2/M transition of mitotic cell cycle);GO:0016579(protein deubiquitination);GO:0031145(anaphase-promoting complex-dependent catabolic process);GO:0031146(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process);GO:0033209(tumor necrosis factor-mediated signaling pathway);GO:0038061(NIK/NF-kappaB signaling);GO:0043161(proteasome-mediated ubiquitin-dependent protein catabolic process);GO:0043488(regulation of mRNA stability);GO:0043687(post-translational protein modification);GO:0050852(T cell receptor signaling pathway);GO:0051437(positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition);GO:0055085(transmembrane transport);GO:0060071(Wnt signaling pathway, planar cell polarity pathway);GO:0061418(regulation of transcription from RNA polymerase II promoter in response to hypoxia);GO:0090090(negative regulation of canonical Wnt signaling pathway);GO:0090263(positive regulation of canonical Wnt signaling pathway);GO:1902036(regulation of hematopoietic stem cell differentiation);GO:0001824(blastocyst development);GO:0016234(inclusion body);GO:0022624(proteasome accessory complex);GO:0031597(cytosolic proteasome complex);GO:0045202(synapse);GO:0051436(negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle);GO:0031595(nuclear proteasome complex);GO:0006508(proteolysis);GO:0030433(ubiquitin-dependent ERAD pathway);GO:0017025(TBP-class protein binding);GO:0045899(positive regulation of RNA polymerase II transcriptional preinitiation complex assembly);GO:0008540(proteasome regulatory particle, base subcomplex);GO:0016887(ATPase activity)","03050(Proteasome);05169(Epstein-Barr virus infection)","NA","NA","proteasome 26S subunit, ATPase 4 [Source:HGNC Symbol;Acc:HGNC:9551]",{"v":0.656434,"d":"0.66"},{"v":2.831904,"d":"2.83"},{"v":0.231799524277659,"d":"0.23"},{"v":-2.10905048938407,"d":"-2.11"},{"v":1.14620052767596E-3,"d":"0.00"},{"v":0.0232387459443155,"d":"0.02"},"down","yes"]
[111140,0,"chr2","+",73986404,74108176,"ENST00000409262",11,11388,"ENSG00000187605","TET3","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0016569(covalent chromatin modification);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0007275(multicellular organism development);GO:0051213(dioxygenase activity);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0006493(protein O-linked glycosylation);GO:0080182(histone H3-K4 trimethylation);GO:0070579(methylcytosine dioxygenase activity);GO:0044727(DNA demethylation of male pronucleus);GO:0080111(DNA demethylation);GO:0001940(male pronucleus)","NA","NA","NA","tet methylcytosine dioxygenase 3 [Source:HGNC Symbol;Acc:HGNC:28313]",{"v":7.269394,"d":"7.27"},{"v":1.354616,"d":"1.35"},{"v":5.36638722708133,"d":"5.37"},{"v":2.42395116015824,"d":"2.42"},{"v":0.00115269540492367,"d":"0.00"},{"v":0.0233465063179423,"d":"0.02"},"up","yes"]
[173918,0,"chr7","-",47964320,47979553,"ENST00000458191",9,1304,"MSTRG.13637","HUS1","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0000077(DNA damage checkpoint);GO:0005515(protein binding);GO:0006974(cellular response to DNA damage stimulus);GO:0005730(nucleolus);GO:0030896(checkpoint clamp complex);GO:0005654(nucleoplasm);GO:0031573(intra-S DNA damage checkpoint);GO:1901796(regulation of signal transduction by p53 class mediator);GO:0006260(DNA replication);GO:0006281(DNA repair);GO:0071479(cellular response to ionizing radiation);GO:0000724(double-strand break repair via homologous recombination);GO:0006289(nucleotide-excision repair);GO:0033314(mitotic DNA replication checkpoint);GO:0044778(meiotic DNA integrity checkpoint);GO:0035861(site of double-strand break);GO:0001932(regulation of protein phosphorylation);GO:0006468(protein phosphorylation);GO:0007093(mitotic cell cycle checkpoint);GO:0008156(negative regulation of DNA replication);GO:0009411(response to UV);GO:0009790(embryo development)","04218(Cellular senescence)","NA","NA","HUS1 checkpoint clamp component [Source:HGNC Symbol;Acc:HGNC:5309]",{"v":0.631617,"d":"0.63"},{"v":2.764927,"d":"2.76"},{"v":0.22843894251096,"d":"0.23"},{"v":-2.13011948368565,"d":"-2.13"},{"v":0.00115558988528857,"d":"0.00"},{"v":0.023381199028722,"d":"0.02"},"down","yes"]
[86779,0,"chr17","+",63773863,63819317,"ENST00000578681",19,4337,"MSTRG.7135","DDX42","GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016607(nuclear speck);GO:0016020(membrane);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0005829(cytosol);GO:0016787(hydrolase activity);GO:0004386(helicase activity);GO:0005730(nucleolus);GO:0005515(protein binding);GO:0005654(nucleoplasm);GO:0004004(ATP-dependent RNA helicase activity);GO:0010501(RNA secondary structure unwinding);GO:0042981(regulation of apoptotic process);GO:0015030(Cajal body);GO:0000398(mRNA splicing, via spliceosome);GO:0008104(protein localization)","03040(Spliceosome)","K12835","EC:3.6.4.13","DEAD-box helicase 42 [Source:HGNC Symbol;Acc:HGNC:18676]",{"v":0.790773,"d":"0.79"},{"v":3.26174,"d":"3.26"},{"v":0.242439004948279,"d":"0.24"},{"v":-2.04430626852488,"d":"-2.04"},{"v":0.00115735603733961,"d":"0.00"},{"v":0.0233930145729073,"d":"0.02"},"down","yes"]
[100365,0,"chr19","-",35904401,35908295,"ENST00000587837",5,570,"MSTRG.8084","TYROBP","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005515(protein binding);GO:0050776(regulation of immune response);GO:0005886(plasma membrane);GO:0042802(identical protein binding);GO:0045087(innate immune response);GO:0005887(integral component of plasma membrane);GO:0005102(receptor binding);GO:0043312(neutrophil degranulation);GO:0007165(signal transduction);GO:0009986(cell surface);GO:0030667(secretory granule membrane);GO:0035556(intracellular signal transduction);GO:0005057(signal transducer activity, downstream of receptor);GO:0006968(cellular defense response);GO:0002281(macrophage activation involved in immune response);GO:0002283(neutrophil activation involved in immune response);GO:0007229(integrin-mediated signaling pathway);GO:2001204(regulation of osteoclast development)","04650(Natural killer cell mediated cytotoxicity);04380(Osteoclast differentiation)","K07992","NA","TYRO protein tyrosine kinase binding protein [Source:HGNC Symbol;Acc:HGNC:12449]",{"v":13.282806,"d":"13.28"},{"v":54.194843,"d":"54.19"},{"v":0.245093541464822,"d":"0.25"},{"v":-2.02859562708179,"d":"-2.03"},{"v":1.16155626003237E-3,"d":"0.00"},{"v":0.0234539543607352,"d":"0.02"},"down","yes"]
[67587,0,"chr16","-",681671,684528,"ENST00000567120",8,2205,"MSTRG.5487","JMJD8","GO:0070062(extracellular exosome)","NA","NA","NA","jumonji domain containing 8 [Source:HGNC Symbol;Acc:HGNC:14148]",{"v":0.368673,"d":"0.37"},{"v":1.608461,"d":"1.61"},{"v":0.229208541581052,"d":"0.23"},{"v":-2.12526728697487,"d":"-2.13"},{"v":0.00116459110175069,"d":"0.00"},{"v":0.0234805731369255,"d":"0.02"},"down","yes"]
[116552,0,"chr2","-",174560770,174682899,"ENST00000272746",9,3028,"MSTRG.9248","WIPF1","GO:0005737(cytoplasm);GO:0003779(actin binding);GO:0015629(actin cytoskeleton);GO:0008154(actin polymerization or depolymerization);GO:0005856(cytoskeleton);GO:0042995(cell projection);GO:0005515(protein binding);GO:0031410(cytoplasmic vesicle);GO:0038096(Fc-gamma receptor signaling pathway involved in phagocytosis);GO:0030048(actin filament-based movement);GO:0051707(response to other organism);GO:0005884(actin filament);GO:0005829(cytosol);GO:0017124(SH3 domain binding);GO:0001726(ruffle);GO:0006461(protein complex assembly);GO:0005522(profilin binding)","04144(Endocytosis)","NA","NA","WAS/WASL interacting protein family member 1 [Source:HGNC Symbol;Acc:HGNC:12736]",{"v":3.109785,"d":"3.11"},{"v":0.559934,"d":"0.56"},{"v":5.55384205995707,"d":"5.55"},{"v":2.47348615040908,"d":"2.47"},{"v":1.16537506429623E-3,"d":"0.00"},{"v":0.0234805731369255,"d":"0.02"},"up","yes"]
[23194,"j","chr10","-",103088017,103181329,"MSTRG.1950.1",18,3510,"MSTRG.1950","NT5C2","NA","NA","NA","NA","NA",{"v":1.611697,"d":"1.61"},{"v":6.595234,"d":"6.60"},{"v":0.244372982065534,"d":"0.24"},{"v":-2.03284330561752,"d":"-2.03"},{"v":0.00116643437404476,"d":"0.00"},{"v":0.0234805731369255,"d":"0.02"},"down","yes"]
[128584,0,"chr22","-",19846138,19854896,"ENST00000407472",3,6523,"ENSG00000215012","RTL10","GO:0005739(mitochondrion);GO:0006915(apoptotic process);GO:0005515(protein binding);GO:0051881(regulation of mitochondrial membrane potential);GO:0097345(mitochondrial outer membrane permeabilization)","NA","NA","NA","retrotransposon Gag like 10 [Source:HGNC Symbol;Acc:HGNC:26112]",{"v":2.026116,"d":"2.03"},{"v":0.368274,"d":"0.37"},{"v":5.5016536600466,"d":"5.50"},{"v":2.45986532201321,"d":"2.46"},{"v":1.16792978309686E-3,"d":"0.00"},{"v":0.0234867830771551,"d":"0.02"},"up","yes"]
[191341,0,"chr9","-",83661429,83707934,"ENST00000257468",10,2299,"MSTRG.14814","UBQLN1","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0005783(endoplasmic reticulum);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0000502(proteasome complex);GO:0048471(perinuclear region of cytoplasm);GO:0006914(autophagy);GO:0031410(cytoplasmic vesicle);GO:0042802(identical protein binding);GO:0000045(autophagosome assembly);GO:0005776(autophagosome);GO:0031398(positive regulation of protein ubiquitination);GO:0030433(ubiquitin-dependent ERAD pathway);GO:0016236(macroautophagy);GO:0071456(cellular response to hypoxia);GO:0034976(response to endoplasmic reticulum stress);GO:0016235(aggresome);GO:0019900(kinase binding);GO:1902175(regulation of oxidative stress-induced intrinsic apoptotic signaling pathway);GO:0043234(protein complex);GO:0031593(polyubiquitin binding);GO:1903071(positive regulation of ER-associated ubiquitin-dependent protein catabolic process);GO:0097352(autophagosome maturation);GO:0035973(aggrephagy);GO:0031396(regulation of protein ubiquitination);GO:0034140(negative regulation of toll-like receptor 3 signaling pathway);GO:1901340(negative regulation of store-operated calcium channel activity)","04141(Protein processing in endoplasmic reticulum)","K04523","NA","ubiquilin 1 [Source:HGNC Symbol;Acc:HGNC:12508]",{"v":1.215863,"d":"1.22"},{"v":5.024359,"d":"5.02"},{"v":0.24199365531006,"d":"0.24"},{"v":-2.04695887206809,"d":"-2.05"},{"v":0.00117330234111766,"d":"0.00"},{"v":0.0235708697726256,"d":"0.02"},"down","yes"]
[98440,0,"chr19","-",17824786,17848032,"ENST00000458235",24,5432,"MSTRG.7976","JAK3","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0035556(intracellular signal transduction);GO:0004713(protein tyrosine kinase activity);GO:0018108(peptidyl-tyrosine phosphorylation);GO:0043547(positive regulation of GTPase activity);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0004715(non-membrane spanning protein tyrosine kinase activity);GO:0002376(immune system process);GO:0045087(innate immune response);GO:0002250(adaptive immune response);GO:0006954(inflammatory response);GO:0005829(cytosol);GO:0000165(MAPK cascade);GO:0012505(endomembrane system);GO:0019903(protein phosphatase binding);GO:0042981(regulation of apoptotic process);GO:0038111(interleukin-7-mediated signaling pathway);GO:0016477(cell migration);GO:0005088(Ras guanyl-nucleotide exchange factor activity);GO:0005102(receptor binding);GO:0032695(negative regulation of interleukin-12 production);GO:0043029(T cell homeostasis);GO:0007167(enzyme linked receptor protein signaling pathway);GO:0030218(erythrocyte differentiation);GO:0038083(peptidyl-tyrosine autophosphorylation);GO:0060397(JAK-STAT cascade involved in growth hormone signaling pathway);GO:0031234(extrinsic component of cytoplasmic side of plasma membrane);GO:0007262(STAT protein import into nucleus);GO:0030183(B cell differentiation);GO:0070244(negative regulation of thymocyte apoptotic process);GO:0007260(tyrosine phosphorylation of STAT protein);GO:0070232(regulation of T cell apoptotic process);GO:0042102(positive regulation of T cell proliferation);GO:0045626(negative regulation of T-helper 1 cell differentiation);GO:0032693(negative regulation of interleukin-10 production);GO:0002731(negative regulation of dendritic cell cytokine production);GO:0035771(interleukin-4-mediated signaling pathway);GO:0045221(negative regulation of FasL biosynthetic process);GO:0050868(negative regulation of T cell activation);GO:0070669(response to interleukin-2);GO:0070670(response to interleukin-4);GO:0070672(response to interleukin-15);GO:0071104(response to interleukin-9)","04630(Jak-STAT signaling pathway);04151(PI3K-Akt signaling pathway);04217(Necroptosis);04550(Signaling pathways regulating pluripotency of stem cells);04658(Th1 and Th2 cell differentiation);04659(Th17 cell differentiation);04062(Chemokine signaling pathway);05200(Pathways in cancer);05203(Viral carcinogenesis);05223(Non-small cell lung cancer);05340(Primary immunodeficiency);05166(HTLV-I infection);05162(Measles);05169(Epstein-Barr virus infection)","K11218","EC:2.7.10.2","Janus kinase 3 [Source:HGNC Symbol;Acc:HGNC:6193]",{"v":12.942746,"d":"12.94"},{"v":2.419272,"d":"2.42"},{"v":5.3498515255829,"d":"5.35"},{"v":2.41949885295722,"d":"2.42"},{"v":1.18008886124992E-3,"d":"0.00"},{"v":0.0236682812802933,"d":"0.02"},"up","yes"]
[114280,0,"chr2","+",128091311,128195677,"ENST00000259253",41,10650,"MSTRG.9097","UGGT1","GO:0006486(protein glycosylation);GO:0003980(UDP-glucose:glycoprotein glucosyltransferase activity);GO:0097359(UDP-glucosylation);GO:0016740(transferase activity);GO:0016757(transferase activity, transferring glycosyl groups);GO:0005783(endoplasmic reticulum);GO:0044322(endoplasmic reticulum quality control compartment);GO:0005788(endoplasmic reticulum lumen);GO:0005515(protein binding);GO:0070062(extracellular exosome);GO:0043234(protein complex);GO:1904380(endoplasmic reticulum mannose trimming);GO:0051082(unfolded protein binding);GO:0005793(endoplasmic reticulum-Golgi intermediate compartment);GO:0051084('de novo' posttranslational protein folding);GO:0018279(protein N-linked glycosylation via asparagine);GO:0030968(endoplasmic reticulum unfolded protein response);GO:0071712(ER-associated misfolded protein catabolic process)","04141(Protein processing in endoplasmic reticulum)","K11718","EC:2.4.1.-","UDP-glucose glycoprotein glucosyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:15663]",{"v":4.126933,"d":"4.13"},{"v":0.768828,"d":"0.77"},{"v":5.36782349238061,"d":"5.37"},{"v":2.42433723285445,"d":"2.42"},{"v":1.18054344166412E-3,"d":"0.00"},{"v":0.0236682812802933,"d":"0.02"},"up","yes"]
[183064,0,"chr8","-",38269697,38382272,"ENST00000317025",24,10776,"MSTRG.14317","NSD3","GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0008168(methyltransferase activity);GO:0016740(transferase activity);GO:0032259(methylation);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0016569(covalent chromatin modification);GO:0005694(chromosome);GO:0005515(protein binding);GO:0018024(histone-lysine N-methyltransferase activity);GO:0034968(histone lysine methylation);GO:0005654(nucleoplasm);GO:0016571(histone methylation)","00310(Lysine degradation)","K11425","EC:2.1.1.43","nuclear receptor binding SET domain protein 3 [Source:HGNC Symbol;Acc:HGNC:12767]",{"v":4.059112,"d":"4.06"},{"v":0.755491,"d":"0.76"},{"v":5.37281317712587,"d":"5.37"},{"v":2.42567767368248,"d":"2.43"},{"v":0.0011832977609048,"d":"0.00"},{"v":0.0236994899724536,"d":"0.02"},"up","yes"]
[89933,0,"chr17","+",82458726,82488065,"ENST00000582907",12,1454,"MSTRG.7368","NARF","GO:0005634(nucleus);GO:0005730(nucleolus);GO:0055114(oxidation-reduction process);GO:0003954(NADH dehydrogenase activity);GO:0005521(lamin binding);GO:0005638(lamin filament);GO:0005652(nuclear lamina);GO:0031981(nuclear lumen)","NA","NA","NA","nuclear prelamin A recognition factor [Source:HGNC Symbol;Acc:HGNC:29916]",{"v":1.013961,"d":"1.01"},{"v":4.284734,"d":"4.28"},{"v":0.23664502860621,"d":"0.24"},{"v":-2.079203480356,"d":"-2.08"},{"v":0.00118463086498391,"d":"0.00"},{"v":0.0237021997535911,"d":"0.02"},"down","yes"]
[145811,0,"chr4","+",8199371,8241091,"ENST00000515682",18,4293,"ENSG00000125089","SH3TC1","GO:0008150(biological_process);GO:0005575(cellular_component)","NA","NA","NA","SH3 domain and tetratricopeptide repeats 1 [Source:HGNC Symbol;Acc:HGNC:26009]",{"v":1.40819,"d":"1.41"},{"v":0.250699,"d":"0.25"},{"v":5.61705471501681,"d":"5.62"},{"v":2.48981385609419,"d":"2.49"},{"v":0.00118697132526316,"d":"0.00"},{"v":0.023725038974048,"d":"0.02"},"up","yes"]
[101248,0,"chr19","+",39391323,39400561,"ENST00000615911",4,3565,"MSTRG.8133","MED29","GO:0005654(nucleoplasm);GO:0016592(mediator complex);GO:0005634(nucleus);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0005515(protein binding)","NA","NA","NA","mediator complex subunit 29 [Source:HGNC Symbol;Acc:HGNC:23074]",{"v":3.815499,"d":"3.82"},{"v":0.699838,"d":"0.70"},{"v":5.45197459983596,"d":"5.45"},{"v":2.44677884079755,"d":"2.45"},{"v":0.00119672615628437,"d":"0.00"},{"v":0.0238681521538768,"d":"0.02"},"up","yes"]
[101247,0,"chr19","+",39391311,39400637,"ENST00000315588",4,3653,"MSTRG.8133","MED29","GO:0005654(nucleoplasm);GO:0016592(mediator complex);GO:0005634(nucleus);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0005515(protein binding)","NA","NA","NA","mediator complex subunit 29 [Source:HGNC Symbol;Acc:HGNC:23074]",{"v":3.723584,"d":"3.72"},{"v":0.682979,"d":"0.68"},{"v":5.45197436524403,"d":"5.45"},{"v":2.44677877872011,"d":"2.45"},{"v":0.00119672615628437,"d":"0.00"},{"v":0.0238681521538768,"d":"0.02"},"up","yes"]
[111348,"j","chr2","-",74526648,74529723,"MSTRG.8842.2",11,1740,"MSTRG.8842","AUP1","NA","NA","NA","NA","NA",{"v":0.80668,"d":"0.81"},{"v":3.411474,"d":"3.41"},{"v":0.236460837749313,"d":"0.24"},{"v":-2.08032682829203,"d":"-2.08"},{"v":1.1977499034162E-3,"d":"0.00"},{"v":0.0238681521538768,"d":"0.02"},"down","yes"]
[187362,0,"chr8","+",132775384,132848807,"ENST00000395386",21,6237,"ENSG00000129292","PHF20L1","GO:0005634(nucleus);GO:0006355(regulation of transcription, DNA-templated);GO:0046872(metal ion binding);GO:0005515(protein binding)","NA","NA","NA","PHD finger protein 20 like 1 [Source:HGNC Symbol;Acc:HGNC:24280]",{"v":1.613914,"d":"1.61"},{"v":0.295289,"d":"0.30"},{"v":5.46554053825236,"d":"5.47"},{"v":2.45036418451427,"d":"2.45"},{"v":0.00121112927250364,"d":"0.00"},{"v":0.0241013515974903,"d":"0.02"},"up","yes"]
[175032,0,"chr7","+",74210006,74229831,"ENST00000275635",14,1869,"MSTRG.13713","LAT2","GO:0042113(B cell activation);GO:0002764(immune response-regulating signaling pathway);GO:0005622(intracellular);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005886(plasma membrane);GO:0002376(immune system process);GO:0002250(adaptive immune response);GO:0038095(Fc-epsilon receptor signaling pathway);GO:0042629(mast cell granule);GO:0070062(extracellular exosome);GO:0005515(protein binding);GO:0043303(mast cell degranulation);GO:0019722(calcium-mediated signaling);GO:0035556(intracellular signal transduction);GO:0045121(membrane raft);GO:0042169(SH2 domain binding);GO:0050853(B cell receptor signaling pathway)","NA","NA","NA","linker for activation of T-cells family member 2 [Source:HGNC Symbol;Acc:HGNC:12749]",{"v":11.012576,"d":"11.01"},{"v":44.42421,"d":"44.42"},{"v":0.247895820769801,"d":"0.25"},{"v":-2.01219414538893,"d":"-2.01"},{"v":1.21188825750469E-3,"d":"0.00"},{"v":0.0241013515974903,"d":"0.02"},"down","yes"]
[131360,"j","chr22","-",38734688,38755956,"MSTRG.10462.2",19,4029,"MSTRG.10462","SUN2","NA","NA","NA","NA","NA",{"v":37.756351,"d":"37.76"},{"v":7.101867,"d":"7.10"},{"v":5.31639792747456,"d":"5.32"},{"v":2.41044909304687,"d":"2.41"},{"v":0.00121518497220904,"d":"0.00"},{"v":0.024142650833406,"d":"0.02"},"up","yes"]
[119145,0,"chr2","-",218638145,218659655,"ENST00000450765",11,6028,"ENSG00000115568","ZNF142","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0003674(molecular_function);GO:0008150(biological_process);GO:0005575(cellular_component)","NA","NA","NA","zinc finger protein 142 [Source:HGNC Symbol;Acc:HGNC:12927]",{"v":0.193169,"d":"0.19"},{"v":0.825542,"d":"0.83"},{"v":0.233990517744706,"d":"0.23"},{"v":-2.09547802781317,"d":"-2.10"},{"v":0.00122244162763363,"d":"0.00"},{"v":0.0242591013454829,"d":"0.02"},"down","yes"]
[101277,0,"chr19","-",39433207,39435948,"ENST00000251453",5,560,"MSTRG.8134","RPS16","GO:0030529(intracellular ribonucleoprotein complex);GO:0003735(structural constituent of ribosome);GO:0006412(translation);GO:0005840(ribosome);GO:0003723(RNA binding);GO:0016020(membrane);GO:0005515(protein binding);GO:0022627(cytosolic small ribosomal subunit);GO:0005925(focal adhesion);GO:0006364(rRNA processing);GO:0042274(ribosomal small subunit biogenesis);GO:0000462(maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA));GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0031012(extracellular matrix);GO:0006413(translational initiation);GO:0000184(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay);GO:0019083(viral transcription);GO:0006614(SRP-dependent cotranslational protein targeting to membrane);GO:0097421(liver regeneration);GO:1990830(cellular response to leukemia inhibitory factor);GO:0015935(small ribosomal subunit)","03010(Ribosome)","K02960","NA","ribosomal protein S16 [Source:HGNC Symbol;Acc:HGNC:10396]",{"v":229.418091,"d":"229.42"},{"v":921.957825,"d":"921.96"},{"v":0.24883794548845,"d":"0.25"},{"v":-2.00672159497416,"d":"-2.01"},{"v":1.22349823846735E-3,"d":"0.00"},{"v":0.0242591013454829,"d":"0.02"},"down","yes"]
[100360,0,"chr19","+",35902480,35904377,"ENST00000246551",4,613,"MSTRG.8083","HCST","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005102(receptor binding);GO:0050776(regulation of immune response);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0043548(phosphatidylinositol 3-kinase binding);GO:0009986(cell surface);GO:0014068(positive regulation of phosphatidylinositol 3-kinase signaling);GO:0006468(protein phosphorylation)","04650(Natural killer cell mediated cytotoxicity)","K07988","NA","hematopoietic cell signal transducer [Source:HGNC Symbol;Acc:HGNC:16977]",{"v":6.547374,"d":"6.55"},{"v":26.771152,"d":"26.77"},{"v":0.244568257652865,"d":"0.24"},{"v":-2.03169092527591,"d":"-2.03"},{"v":0.00122907372677051,"d":"0.00"},{"v":0.0243452561614963,"d":"0.02"},"down","yes"]
[100469,0,"chr19","+",36141303,36146228,"ENST00000592354",8,690,"MSTRG.8090","CAPNS1","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0046872(metal ion binding);GO:0005509(calcium ion binding);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0006508(proteolysis);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0022617(extracellular matrix disassembly);GO:0004198(calcium-dependent cysteine-type endopeptidase activity);GO:0016241(regulation of macroautophagy);GO:0070268(cornification);GO:0008284(positive regulation of cell proliferation);GO:0004175(endopeptidase activity)","NA","NA","NA","calpain small subunit 1 [Source:HGNC Symbol;Acc:HGNC:1481]",{"v":1.796544,"d":"1.80"},{"v":7.425492,"d":"7.43"},{"v":0.241942756116362,"d":"0.24"},{"v":-2.04726235001631,"d":"-2.05"},{"v":0.00133211126390198,"d":"0.00"},{"v":0.0257122692030241,"d":"0.03"},"down","yes"]
[113153,0,"chr2","+",105851782,105894272,"ENST00000393349",4,2371,"MSTRG.9025","NCK2","GO:0005737(cytoplasm);GO:0005783(endoplasmic reticulum);GO:0005515(protein binding);GO:0005070(SH3/SH2 adaptor activity);GO:0032403(protein complex binding);GO:0097110(scaffold protein binding);GO:0001771(immunological synapse formation);GO:0007015(actin filament organization);GO:0016477(cell migration);GO:0030032(lamellipodium assembly);GO:0036493(positive regulation of translation in response to endoplasmic reticulum stress);GO:0048013(ephrin receptor signaling pathway);GO:0060996(dendritic spine development);GO:1902237(positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway);GO:1903898(negative regulation of PERK-mediated unfolded protein response);GO:1903912(negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation);GO:1990441(negative regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress);GO:0012506(vesicle membrane);GO:0014069(postsynaptic density);GO:0045202(synapse);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0005829(cytosol);GO:0006417(regulation of translation);GO:0042102(positive regulation of T cell proliferation);GO:0007165(signal transduction);GO:0042110(T cell activation);GO:0001784(phosphotyrosine residue binding);GO:0048010(vascular endothelial growth factor receptor signaling pathway);GO:0008093(cytoskeletal adaptor activity);GO:0008285(negative regulation of cell proliferation);GO:0030838(positive regulation of actin filament polymerization);GO:0030159(receptor signaling complex scaffold activity);GO:0007172(signal complex assembly);GO:0007173(epidermal growth factor receptor signaling pathway);GO:0007176(regulation of epidermal growth factor-activated receptor activity);GO:0033137(negative regulation of peptidyl-serine phosphorylation)","04012(ErbB signaling pathway);04660(T cell receptor signaling pathway);04360(Axon guidance);05130(Pathogenic Escherichia coli infection)","K19862","NA","NCK adaptor protein 2 [Source:HGNC Symbol;Acc:HGNC:7665]",{"v":2.132338,"d":"2.13"},{"v":0.405079,"d":"0.41"},{"v":5.26400529279474,"d":"5.26"},{"v":2.39616093965919,"d":"2.40"},{"v":1.86238131114265E-3,"d":"0.00"},{"v":0.0324694285329434,"d":"0.03"},"up","yes"]
[103963,0,"chr19","-",49555711,49580535,"ENST00000598820",8,2615,"MSTRG.8321","NOSIP","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0050999(regulation of nitric-oxide synthase activity);GO:0003723(RNA binding);GO:0016740(transferase activity);GO:0007275(multicellular organism development);GO:0061630(ubiquitin protein ligase activity);GO:0005515(protein binding);GO:0005829(cytosol);GO:0016567(protein ubiquitination);GO:0000139(Golgi membrane);GO:0043086(negative regulation of catalytic activity);GO:0051001(negative regulation of nitric-oxide synthase activity);GO:0004842(ubiquitin-protein transferase activity)","NA","NA","NA","nitric oxide synthase interacting protein [Source:HGNC Symbol;Acc:HGNC:17946]",{"v":0.592358,"d":"0.59"},{"v":2.237423,"d":"2.24"},{"v":0.264750116540323,"d":"0.26"},{"v":-1.91729677560985,"d":"-1.92"},{"v":2.3881758557011E-3,"d":"0.00"},{"v":0.0385144448513557,"d":"0.04"},"down","yes"]
[98765,0,"chr19","-",18990888,19033499,"ENST00000452918",11,6176,"MSTRG.8011","SUGP2","GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0006396(RNA processing);GO:0006397(mRNA processing);GO:0008380(RNA splicing);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0016604(nuclear body)","NA","NA","NA","SURP and G-patch domain containing 2 [Source:HGNC Symbol;Acc:HGNC:18641]",{"v":4.915615,"d":"4.92"},{"v":1.103381,"d":"1.10"},{"v":4.45504771244022,"d":"4.46"},{"v":2.15544088273088,"d":"2.16"},{"v":4.09542381440224E-3,"d":"0.00"},{"v":0.055937491984421,"d":"0.06"},"up","yes"]
[158293,0,"chr5","+",132866560,132868031,"ENST00000378670",3,839,"MSTRG.12283","UQCRQ","GO:0016020(membrane);GO:0055114(oxidation-reduction process);GO:0005739(mitochondrion);GO:0005743(mitochondrial inner membrane);GO:1902600(hydrogen ion transmembrane transport);GO:0070469(respiratory chain);GO:0008121(ubiquinol-cytochrome-c reductase activity);GO:0006122(mitochondrial electron transport, ubiquinol to cytochrome c);GO:0005750(mitochondrial respiratory chain complex III);GO:0021539(subthalamus development);GO:0021548(pons development);GO:0021680(cerebellar Purkinje cell layer development);GO:0021766(hippocampus development);GO:0021794(thalamus development);GO:0021854(hypothalamus development);GO:0021860(pyramidal neuron development);GO:0030901(midbrain development)","00190(Oxidative phosphorylation);04260(Cardiac muscle contraction);05010(Alzheimer's disease);05012(Parkinson's disease);05016(Huntington's disease);04932(Non-alcoholic fatty liver disease (NAFLD))","K00418","NA","ubiquinol-cytochrome c reductase complex III subunit VII [Source:HGNC Symbol;Acc:HGNC:29594]",{"v":3.992676,"d":"3.99"},{"v":13.121824,"d":"13.12"},{"v":0.304277515077172,"d":"0.30"},{"v":-1.71654036663848,"d":"-1.72"},{"v":0.00503792699583114,"d":"0.01"},{"v":0.0647301041887486,"d":"0.06"},"down","yes"]
[177588,0,"chr7","-",106271865,106284887,"ENST00000486949",4,1115,"MSTRG.13893","NAMPT","GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016607(nuclear speck);GO:0016740(transferase activity);GO:0016757(transferase activity, transferring glycosyl groups);GO:0030054(cell junction);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0048511(rhythmic process);GO:0005125(cytokine activity);GO:0005615(extracellular space);GO:0009435(NAD biosynthetic process);GO:0019363(pyridine nucleotide biosynthetic process);GO:0004514(nicotinate-nucleotide diphosphorylase (carboxylating) activity);GO:0008144(drug binding);GO:0042803(protein homodimerization activity);GO:0047280(nicotinamide phosphoribosyltransferase activity);GO:0007565(female pregnancy);GO:0007623(circadian rhythm);GO:0014070(response to organic cyclic compound);GO:0032922(circadian regulation of gene expression);GO:0048661(positive regulation of smooth muscle cell proliferation);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0007165(signal transduction);GO:0007267(cell-cell signaling);GO:0051770(positive regulation of nitric-oxide synthase biosynthetic process);GO:0008284(positive regulation of cell proliferation);GO:0034356(NAD biosynthesis via nicotinamide riboside salvage pathway)","00760(Nicotinate and nicotinamide metabolism);04621(NOD-like receptor signaling pathway)","NA","NA","nicotinamide phosphoribosyltransferase [Source:HGNC Symbol;Acc:HGNC:30092]",{"v":3.754513,"d":"3.75"},{"v":0.86101,"d":"0.86"},{"v":4.36059163075922,"d":"4.36"},{"v":2.12452388840973,"d":"2.12"},{"v":0.00613359367904926,"d":"0.01"},{"v":0.0743375196899217,"d":"0.07"},"up","yes"]
[113279,0,"chr2","+",108621266,108684448,"ENST00000409441",10,1627,"MSTRG.9034","LIMS1","GO:0046872(metal ion binding);GO:0016020(membrane);GO:0008270(zinc ion binding);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0048471(perinuclear region of cytoplasm);GO:0030054(cell junction);GO:0005925(focal adhesion);GO:0005829(cytosol);GO:0019901(protein kinase binding);GO:0010628(positive regulation of gene expression);GO:0043547(positive regulation of GTPase activity);GO:0045892(negative regulation of transcription, DNA-templated);GO:0071560(cellular response to transforming growth factor beta stimulus);GO:0005911(cell-cell junction);GO:0045184(establishment of protein localization);GO:1901224(positive regulation of NIK/NF-kappaB signaling);GO:0010811(positive regulation of cell-substrate adhesion);GO:1900026(positive regulation of substrate adhesion-dependent cell spreading);GO:0051894(positive regulation of focal adhesion assembly);GO:0034329(cell junction assembly);GO:0033209(tumor necrosis factor-mediated signaling pathway);GO:0007569(cell aging);GO:0051291(protein heterooligomerization);GO:0043234(protein complex)","NA","NA","NA","LIM zinc finger domain containing 1 [Source:HGNC Symbol;Acc:HGNC:6616]",{"v":0.570257,"d":"0.57"},{"v":1.862391,"d":"1.86"},{"v":0.306196174702305,"d":"0.31"},{"v":-1.70747183547385,"d":"-1.71"},{"v":0.00735663497495158,"d":"0.01"},{"v":0.0836626970599666,"d":"0.08"},"down","yes"]
[20026,0,"chr10","+",45727236,45792961,"ENST00000336378",31,4669,"MSTRG.1697","WASHC2C","GO:0006810(transport);GO:0016020(membrane);GO:0015031(protein transport);GO:0043231(intracellular membrane-bounded organelle);GO:0005730(nucleolus);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0008289(lipid binding);GO:0071203(WASH complex);GO:0005515(protein binding);GO:0005768(endosome);GO:0010314(phosphatidylinositol-5-phosphate binding);GO:0032266(phosphatidylinositol-3-phosphate binding);GO:0080025(phosphatidylinositol-3,5-bisphosphate binding);GO:0005769(early endosome);GO:0042147(retrograde transport, endosome to Golgi);GO:1990126(retrograde transport, endosome to plasma membrane);GO:0031901(early endosome membrane);GO:0005546(phosphatidylinositol-4,5-bisphosphate binding);GO:0005547(phosphatidylinositol-3,4,5-trisphosphate binding);GO:0043325(phosphatidylinositol-3,4-bisphosphate binding);GO:0030904(retromer complex);GO:0070273(phosphatidylinositol-4-phosphate binding);GO:1905394(retromer complex binding);GO:1900024(regulation of substrate adhesion-dependent cell spreading);GO:2000813(negative regulation of barbed-end actin filament capping)","04144(Endocytosis)","NA","NA","WASH complex subunit 2C [Source:HGNC Symbol;Acc:HGNC:23414]",{"v":3.207428,"d":"3.21"},{"v":0.804041,"d":"0.80"},{"v":3.98913488242515,"d":"3.99"},{"v":1.99607590530424,"d":"2.00"},{"v":0.00843169155659722,"d":"0.01"},{"v":0.0910733146953853,"d":"0.09"},"up","yes"]
[33804,0,"chr11","-",85660153,85664653,"ENST00000260058",4,1431,"MSTRG.2785","CREBZF","GO:0005634(nucleus);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0005739(mitochondrion);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0005515(protein binding);GO:0042802(identical protein binding);GO:0009615(response to virus);GO:0051090(regulation of sequence-specific DNA binding transcription factor activity);GO:0045892(negative regulation of transcription, DNA-templated);GO:0045814(negative regulation of gene expression, epigenetic)","NA","NA","NA","CREB/ATF bZIP transcription factor [Source:HGNC Symbol;Acc:HGNC:24905]",{"v":0.523977,"d":"0.52"},{"v":1.62151,"d":"1.62"},{"v":0.323141392899211,"d":"0.32"},{"v":-1.62976252996808,"d":"-1.63"},{"v":0.00989046679929205,"d":"0.01"},{"v":0.100882761352779,"d":"0.10"},"down","yes"]
[153482,0,"chr5","+",10401857,10433684,"ENST00000510792",15,1963,"MSTRG.11972","MARCH6","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0005783(endoplasmic reticulum);GO:0016740(transferase activity);GO:0016567(protein ubiquitination);GO:0005789(endoplasmic reticulum membrane);GO:0044322(endoplasmic reticulum quality control compartment);GO:1904264(ubiquitin protein ligase activity involved in ERAD pathway);GO:0030176(integral component of endoplasmic reticulum membrane);GO:0019899(enzyme binding);GO:0004842(ubiquitin-protein transferase activity);GO:1904380(endoplasmic reticulum mannose trimming);GO:0070936(protein K48-linked ubiquitination);GO:1990381(ubiquitin-specific protease binding);GO:0030433(ubiquitin-dependent ERAD pathway);GO:0036503(ERAD pathway);GO:0031624(ubiquitin conjugating enzyme binding);GO:0010498(proteasomal protein catabolic process);GO:0000835(ER ubiquitin ligase complex)","04141(Protein processing in endoplasmic reticulum)","K10661","EC:2.3.2.27","membrane associated ring-CH-type finger 6 [Source:HGNC Symbol;Acc:HGNC:30550]",{"v":2.254209,"d":"2.25"},{"v":0.577133,"d":"0.58"},{"v":3.90587438250802,"d":"3.91"},{"v":1.96564555120961,"d":"1.97"},{"v":0.0116877486551089,"d":"0.01"},{"v":0.111848524433715,"d":"0.11"},"up","yes"]
[158258,0,"chr5","-",132750817,132777375,"ENST00000378719",10,2889,"ENSG00000164402","SEPT8","GO:0005737(cytoplasm);GO:0005525(GTP binding);GO:0000166(nucleotide binding);GO:0005856(cytoskeleton);GO:0005515(protein binding)","05100(Bacterial invasion of epithelial cells)","K16939","NA","septin 8 [Source:HGNC Symbol;Acc:HGNC:16511]",{"v":0.400627,"d":"0.40"},{"v":1.137475,"d":"1.14"},{"v":0.352207301259368,"d":"0.35"},{"v":-1.50550327833181,"d":"-1.51"},{"v":0.0144424828940808,"d":"0.01"},{"v":0.127812098169978,"d":"0.13"},"down","yes"]
[134970,0,"chr3","+",39406763,39410849,"ENST00000444512",4,701,"MSTRG.10823","RPSA","GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0006412(translation);GO:0007155(cell adhesion);GO:0030529(intracellular ribonucleoprotein complex);GO:0005622(intracellular);GO:0003735(structural constituent of ribosome);GO:0005840(ribosome);GO:0005886(plasma membrane);GO:0015935(small ribosomal subunit);GO:0005515(protein binding);GO:0005055(laminin receptor activity);GO:0043236(laminin binding);GO:0000028(ribosomal small subunit assembly);GO:0022627(cytosolic small ribosomal subunit);GO:0043022(ribosome binding);GO:0046718(viral entry into host cell);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0016032(viral process);GO:0006413(translational initiation);GO:0006364(rRNA processing);GO:0001618(virus receptor activity);GO:0030686(90S preribosome);GO:0000184(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay);GO:0019083(viral transcription);GO:0006614(SRP-dependent cotranslational protein targeting to membrane);GO:0000447(endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA));GO:0000461(endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA));GO:0006407(rRNA export from nucleus);GO:0016337(single organismal cell-cell adhesion);GO:0030855(epithelial cell differentiation);GO:0005604(basement membrane);GO:0031012(extracellular matrix);GO:0043025(neuronal cell body)","03010(Ribosome)","NA","NA","ribosomal protein SA [Source:HGNC Symbol;Acc:HGNC:6502]",{"v":2.285006,"d":"2.29"},{"v":6.252306,"d":"6.25"},{"v":0.365466117621242,"d":"0.37"},{"v":-1.45219043482637,"d":"-1.45"},{"v":0.0167214033417342,"d":"0.02"},{"v":0.141115490638016,"d":"0.14"},"down","yes"]
[43369,0,"chr12","-",57253765,57431005,"ENST00000402412",24,4372,"MSTRG.3484","R3HDM2","GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0005634(nucleus)","NA","NA","NA","R3H domain containing 2 [Source:HGNC Symbol;Acc:HGNC:29167]",{"v":10.517756,"d":"10.52"},{"v":3.068725,"d":"3.07"},{"v":3.42740258576445,"d":"3.43"},{"v":1.77711566205651,"d":"1.78"},{"v":0.0187518400990861,"d":"0.02"},{"v":0.152324060706369,"d":"0.15"},"up","yes"]
[52268,0,"chr14","-",20286228,20305994,"ENST00000258821",10,4779,"ENSG00000136319","TTC5","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005654(nucleoplasm);GO:0005515(protein binding);GO:0006281(DNA repair);GO:0006974(cellular response to DNA damage stimulus);GO:1901796(regulation of signal transduction by p53 class mediator);GO:0003677(DNA binding);GO:0003682(chromatin binding);GO:0045944(positive regulation of transcription from RNA polymerase II promoter)","NA","NA","NA","tetratricopeptide repeat domain 5 [Source:HGNC Symbol;Acc:HGNC:19274]",{"v":0.98249,"d":"0.98"},{"v":2.524087,"d":"2.52"},{"v":0.3892456955723,"d":"0.39"},{"v":-1.36124700936811,"d":"-1.36"},{"v":0.0206090141789764,"d":"0.02"},{"v":0.161217928082742,"d":"0.16"},"down","yes"]
[37558,0,"chr12","-",3615328,3753102,"ENST00000440314",20,2697,"ENSG00000130038","CRACR2A","GO:0006810(transport);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0046872(metal ion binding);GO:0005509(calcium ion binding);GO:0006811(ion transport);GO:0005515(protein binding);GO:0006816(calcium ion transport);GO:0002376(immune system process);GO:0002250(adaptive immune response);GO:0005576(extracellular region);GO:0043312(neutrophil degranulation);GO:0035580(specific granule lumen);GO:0051928(positive regulation of calcium ion transport);GO:0002115(store-operated calcium entry);GO:0032237(activation of store-operated calcium channel activity)","NA","NA","NA","calcium release activated channel regulator 2A [Source:HGNC Symbol;Acc:HGNC:28657]",{"v":2.551937,"d":"2.55"},{"v":0.754903,"d":"0.75"},{"v":3.38048332037361,"d":"3.38"},{"v":1.75722952877289,"d":"1.76"},{"v":0.0229930445543977,"d":"0.02"},{"v":0.172604842808202,"d":"0.17"},"up","yes"]
[61243,0,"chr15","+",40764020,40767710,"ENST00000260447",3,777,"MSTRG.4993","GCHFR","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0042470(melanosome);GO:0030425(dendrite);GO:0005515(protein binding);GO:0009890(negative regulation of biosynthetic process);GO:0031965(nuclear membrane);GO:0050999(regulation of nitric-oxide synthase activity);GO:0006809(nitric oxide biosynthetic process);GO:0004857(enzyme inhibitor activity);GO:0016597(amino acid binding);GO:0019899(enzyme binding);GO:0030742(GTP-dependent protein binding);GO:0044549(GTP cyclohydrolase binding);GO:0006461(protein complex assembly);GO:0042133(neurotransmitter metabolic process);GO:0043105(negative regulation of GTP cyclohydrolase I activity);GO:0051291(protein heterooligomerization);GO:0043234(protein complex);GO:0016787(hydrolase activity)","NA","NA","NA","GTP cyclohydrolase I feedback regulator [Source:HGNC Symbol;Acc:HGNC:4194]",{"v":2.352846,"d":"2.35"},{"v":5.927019,"d":"5.93"},{"v":0.396969538987474,"d":"0.40"},{"v":-1.33289978685852,"d":"-1.33"},{"v":0.0250350564967524,"d":"0.03"},{"v":0.181595930336414,"d":"0.18"},"down","yes"]
[81194,0,"chr17","-",28546708,28552631,"ENST00000301032",4,1653,"MSTRG.6564","UNC119","GO:0006810(transport);GO:0005737(cytoplasm);GO:0015031(protein transport);GO:0007601(visual perception);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0050896(response to stimulus);GO:0000922(spindle pole);GO:0005813(centrosome);GO:0005815(microtubule organizing center);GO:0005819(spindle);GO:0008289(lipid binding);GO:0006897(endocytosis);GO:0051233(spindle midzone);GO:0030182(neuron differentiation);GO:0042953(lipoprotein transport);GO:0007268(chemical synaptic transmission);GO:0007602(phototransduction);GO:0000281(mitotic cytokinesis);GO:0005829(cytosol);GO:0061098(positive regulation of protein tyrosine kinase activity);GO:0045171(intercellular bridge);GO:1900186(negative regulation of clathrin-dependent endocytosis);GO:2001287(negative regulation of caveolin-mediated endocytosis)","NA","NA","NA","unc-119 lipid binding chaperone [Source:HGNC Symbol;Acc:HGNC:12565]",{"v":2.982694,"d":"2.98"},{"v":7.261399,"d":"7.26"},{"v":0.410760240554196,"d":"0.41"},{"v":-1.2836315518177,"d":"-1.28"},{"v":0.0274624186757139,"d":"0.03"},{"v":0.191599419367619,"d":"0.19"},"down","yes"]
[114350,0,"chr2","-",130151409,130182750,"ENST00000409031",20,4896,"MSTRG.9100","SMPD4","GO:0050290(sphingomyelin phosphodiesterase D activity);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0071356(cellular response to tumor necrosis factor);GO:0046872(metal ion binding);GO:0016787(hydrolase activity);GO:0005794(Golgi apparatus);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0000139(Golgi membrane);GO:0006687(glycosphingolipid metabolic process);GO:0004767(sphingomyelin phosphodiesterase activity);GO:0046513(ceramide biosynthetic process);GO:0046475(glycerophospholipid catabolic process);GO:0006685(sphingomyelin catabolic process);GO:0005802(trans-Golgi network)","00600(Sphingolipid metabolism)","K12353","EC:3.1.4.12","sphingomyelin phosphodiesterase 4 [Source:HGNC Symbol;Acc:HGNC:32949]",{"v":1.051294,"d":"1.05"},{"v":0.327394,"d":"0.33"},{"v":3.21109733226632,"d":"3.21"},{"v":1.68306639556812,"d":"1.68"},{"v":0.0298991512987307,"d":"0.03"},{"v":0.202064346277078,"d":"0.20"},"up","yes"]
[19516,0,"chr10","-",32268931,32347185,"ENST00000263062",15,2913,"MSTRG.1647","EPC1","GO:0005634(nucleus);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0016569(covalent chromatin modification);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0005515(protein binding);GO:0004402(histone acetyltransferase activity);GO:0045893(positive regulation of transcription, DNA-templated);GO:0005654(nucleoplasm);GO:0040008(regulation of growth);GO:0032777(Piccolo NuA4 histone acetyltransferase complex);GO:0035267(NuA4 histone acetyltransferase complex);GO:0043967(histone H4 acetylation);GO:0045892(negative regulation of transcription, DNA-templated);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0043968(histone H2A acetylation);GO:0045814(negative regulation of gene expression, epigenetic);GO:0031965(nuclear membrane);GO:0035886(vascular smooth muscle cell differentiation)","NA","NA","NA","enhancer of polycomb homolog 1 [Source:HGNC Symbol;Acc:HGNC:19876]",{"v":1.284344,"d":"1.28"},{"v":0.402284,"d":"0.40"},{"v":3.19263008223046,"d":"3.19"},{"v":1.6747454030652,"d":"1.67"},{"v":0.0338009071061467,"d":"0.03"},{"v":0.217478748248657,"d":"0.22"},"up","yes"]
[191862,"j","chr9","+",93576719,93679587,"MSTRG.14851.3",22,5260,"MSTRG.14851","PHF2","NA","NA","NA","NA","NA",{"v":8.341413,"d":"8.34"},{"v":2.789263,"d":"2.79"},{"v":2.99054373861482,"d":"2.99"},{"v":1.58040781809724,"d":"1.58"},{"v":0.0386149635531202,"d":"0.04"},{"v":0.235771185615006,"d":"0.24"},"up","yes"]
[7179,0,"chr1","-",71063337,71081011,"ENST00000254821",11,2821,"MSTRG.650","ZRANB2","GO:0003723(RNA binding);GO:0006397(mRNA processing);GO:0008380(RNA splicing);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0005654(nucleoplasm);GO:0005515(protein binding);GO:0006355(regulation of transcription, DNA-templated);GO:0003700(transcription factor activity, sequence-specific DNA binding)","NA","NA","NA","zinc finger RANBP2-type containing 2 [Source:HGNC Symbol;Acc:HGNC:13058]",{"v":1.20029,"d":"1.20"},{"v":2.711319,"d":"2.71"},{"v":0.442695971960511,"d":"0.44"},{"v":-1.17561184830732,"d":"-1.18"},{"v":0.0416030938395204,"d":"0.04"},{"v":0.246951595663401,"d":"0.25"},"down","yes"]
[84507,0,"chr17","-",45506741,45515156,"ENST00000579913",4,3243,"ENSG00000214425","LRRC37A4P","NA","NA","NA","NA","leucine rich repeat containing 37 member A4, pseudogene [Source:HGNC Symbol;Acc:HGNC:25479]",{"v":1.609311,"d":"1.61"},{"v":0.540105,"d":"0.54"},{"v":2.9796261837976,"d":"2.98"},{"v":1.57513134524792,"d":"1.58"},{"v":0.0443041214374505,"d":"0.04"},{"v":0.254851731105893,"d":"0.25"},"up","yes"]
[113614,0,"chr2","+",112584441,112589040,"ENST00000324913",4,691,"MSTRG.9057","CHCHD5","GO:0005739(mitochondrion);GO:0009060(aerobic respiration);GO:0005758(mitochondrial intermembrane space)","NA","NA","NA","coiled-coil-helix-coiled-coil-helix domain containing 5 [Source:HGNC Symbol;Acc:HGNC:17840]",{"v":4.517893,"d":"4.52"},{"v":9.977927,"d":"9.98"},{"v":0.452788740587098,"d":"0.45"},{"v":-1.1430900114992,"d":"-1.14"},{"v":0.0470660594462239,"d":"0.05"},{"v":0.263687198279128,"d":"0.26"},"down","yes"]
[90772,0,"chr18","-",11884068,11908330,"ENST00000344987",10,1831,"MSTRG.7429","MPPE1","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005794(Golgi apparatus);GO:0046872(metal ion binding);GO:0005654(nucleoplasm);GO:0016787(hydrolase activity);GO:0006888(ER to Golgi vesicle-mediated transport);GO:0005515(protein binding);GO:0016192(vesicle-mediated transport);GO:0005783(endoplasmic reticulum);GO:0006506(GPI anchor biosynthetic process);GO:0005793(endoplasmic reticulum-Golgi intermediate compartment);GO:0033116(endoplasmic reticulum-Golgi intermediate compartment membrane);GO:0070971(endoplasmic reticulum exit site);GO:0034235(GPI anchor binding);GO:0005801(cis-Golgi network);GO:0030145(manganese ion binding);GO:0008081(phosphoric diester hydrolase activity);GO:0005737(cytoplasm)","NA","NA","NA","metallophosphoesterase 1 [Source:HGNC Symbol;Acc:HGNC:15988]",{"v":1.558393,"d":"1.56"},{"v":3.412387,"d":"3.41"},{"v":0.456687063923289,"d":"0.46"},{"v":-1.13072217024234,"d":"-1.13"},{"v":0.0500696165544662,"d":"0.05"},{"v":0.273382175882709,"d":"0.27"},"down","no"]
[132655,0,"chr22","-",50767504,50783621,"ENST00000354869",9,2140,"ENSG00000079974","RABL2B","GO:0005525(GTP binding);GO:0000166(nucleotide binding);GO:0003924(GTPase activity);GO:0005622(intracellular);GO:0007264(small GTPase mediated signal transduction)","NA","NA","NA","RAB, member of RAS oncogene family like 2B [Source:HGNC Symbol;Acc:HGNC:9800]",{"v":0.424735,"d":"0.42"},{"v":0.94755,"d":"0.95"},{"v":0.448245475172814,"d":"0.45"},{"v":-1.1576390750479,"d":"-1.16"},{"v":0.0537000439433454,"d":"0.05"},{"v":0.284471874697039,"d":"0.28"},"down","no"]
[174828,"j","chr7","+",73220608,73236032,"MSTRG.13701.3",11,1413,"MSTRG.13701","NCF1B","NA","NA","NA","NA","NA",{"v":15.03501,"d":"15.04"},{"v":5.409598,"d":"5.41"},{"v":2.7793211251557,"d":"2.78"},{"v":1.47473253439612,"d":"1.47"},{"v":0.0563109731037356,"d":"0.06"},{"v":0.291388084664636,"d":"0.29"},"up","no"]
[119066,"j","chr2","+",218382229,218395343,"MSTRG.9417.7",15,2891,"MSTRG.9417","SLC11A1","NA","NA","NA","NA","NA",{"v":6.24943,"d":"6.25"},{"v":2.295554,"d":"2.30"},{"v":2.72240600743873,"d":"2.72"},{"v":1.44488223996408,"d":"1.44"},{"v":0.0628541713357825,"d":"0.06"},{"v":0.308701499725109,"d":"0.31"},"up","no"]
[84459,0,"chr17","-",45263121,45317040,"ENST00000344686",16,4460,"MSTRG.6925","MAP3K14","GO:0005737(cytoplasm);GO:0043231(intracellular membrane-bounded organelle);GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0005634(nucleus);GO:0005829(cytosol);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0000165(MAPK cascade);GO:0016310(phosphorylation);GO:0001650(fibrillar center);GO:0005515(protein binding);GO:0006955(immune response);GO:0000186(activation of MAPKK activity);GO:0004709(MAP kinase kinase kinase activity);GO:0051607(defense response to virus);GO:0033209(tumor necrosis factor-mediated signaling pathway);GO:0038061(NIK/NF-kappaB signaling);GO:0043123(positive regulation of I-kappaB kinase/NF-kappaB signaling);GO:0071260(cellular response to mechanical stimulus);GO:0042981(regulation of apoptotic process);GO:0007346(regulation of mitotic cell cycle);GO:0007249(I-kappaB kinase/NF-kappaB signaling);GO:0031295(T cell costimulation);GO:0031098(stress-activated protein kinase signaling cascade);GO:0023014(signal transduction by protein phosphorylation);GO:0032147(activation of protein kinase activity);GO:0004704(NF-kappaB-inducing kinase activity)","04010(MAPK signaling pathway);04064(NF-kappa B signaling pathway);04668(TNF signaling pathway);04210(Apoptosis);04660(T cell receptor signaling pathway);04672(Intestinal immune network for IgA production);04380(Osteoclast differentiation);05120(Epithelial cell signaling in Helicobacter pylori infection);05166(HTLV-I infection);05169(Epstein-Barr virus infection)","K04466","EC:2.7.11.25","mitogen-activated protein kinase kinase kinase 14 [Source:HGNC Symbol;Acc:HGNC:6853]",{"v":6.028035,"d":"6.03"},{"v":2.250726,"d":"2.25"},{"v":2.67826248063958,"d":"2.68"},{"v":1.42129735758544,"d":"1.42"},{"v":0.0669136855883157,"d":"0.07"},{"v":0.320059949340486,"d":"0.32"},"up","no"]
[158302,0,"chr5","-",132875379,132963634,"ENST00000265343",21,9552,"MSTRG.12295","AFF4","GO:0005634(nucleus);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0001650(fibrillar center);GO:0005515(protein binding);GO:0005654(nucleoplasm);GO:0006366(transcription from RNA polymerase II promoter);GO:0006368(transcription elongation from RNA polymerase II promoter);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0008023(transcription elongation factor complex);GO:0035327(transcriptionally active chromatin);GO:0007286(spermatid development)","NA","NA","NA","AF4/FMR2 family member 4 [Source:HGNC Symbol;Acc:HGNC:17869]",{"v":8.443771,"d":"8.44"},{"v":3.198725,"d":"3.20"},{"v":2.63973020500356,"d":"2.64"},{"v":1.40039048572253,"d":"1.40"},{"v":0.0705300491651003,"d":"0.07"},{"v":0.329940570420568,"d":"0.33"},"up","no"]
[42209,0,"chr12","+",53452368,53479614,"ENST00000552296",15,1342,"MSTRG.3414","PCBP2","GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0003677(DNA binding);GO:0030529(intracellular ribonucleoprotein complex);GO:0005515(protein binding);GO:0002376(immune system process);GO:0045087(innate immune response);GO:0005925(focal adhesion);GO:0051607(defense response to virus);GO:0070062(extracellular exosome);GO:0031625(ubiquitin protein ligase binding);GO:0019899(enzyme binding);GO:0075522(IRES-dependent viral translational initiation);GO:0043161(proteasome-mediated ubiquitin-dependent protein catabolic process);GO:0032480(negative regulation of type I interferon production);GO:0000398(mRNA splicing, via spliceosome);GO:0016070(RNA metabolic process);GO:0050687(negative regulation of defense response to virus);GO:0016071(mRNA metabolic process);GO:0039694(viral RNA genome replication)","04216(Ferroptosis)","K13162","NA","poly(rC) binding protein 2 [Source:HGNC Symbol;Acc:HGNC:8648]",{"v":97.36216,"d":"97.36"},{"v":37.302704,"d":"37.30"},{"v":2.61005636481473,"d":"2.61"},{"v":1.3840809624889,"d":"1.38"},{"v":0.0740874551483002,"d":"0.07"},{"v":0.337888870033214,"d":"0.34"},"up","no"]
[103179,0,"chr19","-",46838167,46850992,"ENST00000263270",5,935,"MSTRG.8255","AP2S1","GO:0006810(transport);GO:0008565(protein transporter activity);GO:0006886(intracellular protein transport);GO:0015031(protein transport);GO:0016192(vesicle-mediated transport);GO:0030117(membrane coat);GO:0030122(AP-2 adaptor complex);GO:0016020(membrane);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0005905(clathrin-coated pit);GO:0005829(cytosol);GO:0006897(endocytosis);GO:0061024(membrane organization);GO:0060071(Wnt signaling pathway, planar cell polarity pathway);GO:0007018(microtubule-based movement);GO:0019886(antigen processing and presentation of exogenous peptide antigen via MHC class II);GO:0005215(transporter activity);GO:0048268(clathrin coat assembly);GO:0048013(ephrin receptor signaling pathway);GO:0030666(endocytic vesicle membrane);GO:0034383(low-density lipoprotein particle clearance);GO:0036020(endolysosome membrane);GO:0050690(regulation of defense response to virus by virus);GO:0030669(clathrin-coated endocytic vesicle membrane);GO:0035615(clathrin adaptor activity);GO:0032802(low-density lipoprotein particle receptor catabolic process);GO:0072583(clathrin-dependent endocytosis);GO:0030100(regulation of endocytosis)","04144(Endocytosis);04961(Endocrine and other factor-regulated calcium reabsorption);04721(Synaptic vesicle cycle);05016(Huntington's disease)","K11827","NA","adaptor related protein complex 2 sigma 1 subunit [Source:HGNC Symbol;Acc:HGNC:565]",{"v":11.504879,"d":"11.50"},{"v":22.65365,"d":"22.65"},{"v":0.507859837156485,"d":"0.51"},{"v":-0.977497708403091,"d":"-0.98"},{"v":0.0772317220991732,"d":"0.08"},{"v":0.345135798757552,"d":"0.35"},"down","no"]
[92366,0,"chr18","-",49488484,49492523,"ENST00000580261",7,669,"MSTRG.7521","RPL17","GO:0003723(RNA binding);GO:0005634(nucleus);GO:0006412(translation);GO:0030529(intracellular ribonucleoprotein complex);GO:0005622(intracellular);GO:0003735(structural constituent of ribosome);GO:0005840(ribosome);GO:0015934(large ribosomal subunit);GO:0005829(cytosol);GO:0005515(protein binding);GO:0006413(translational initiation);GO:0006364(rRNA processing);GO:0000184(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay);GO:0019083(viral transcription);GO:0006614(SRP-dependent cotranslational protein targeting to membrane);GO:0022625(cytosolic large ribosomal subunit)","03010(Ribosome)","K02880","NA","ribosomal protein L17 [Source:HGNC Symbol;Acc:HGNC:10307]",{"v":84.899895,"d":"84.90"},{"v":164.81041,"d":"164.81"},{"v":0.51513672589007,"d":"0.52"},{"v":-0.95697269640893,"d":"-0.96"},{"v":0.0806556406452712,"d":"0.08"},{"v":0.353016973501187,"d":"0.35"},"down","no"]
[22860,0,"chr10","-",100523740,100529864,"ENST00000299166",5,671,"MSTRG.1916","NDUFB8","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0055114(oxidation-reduction process);GO:0005739(mitochondrion);GO:0005743(mitochondrial inner membrane);GO:0005747(mitochondrial respiratory chain complex I);GO:0006120(mitochondrial electron transport, NADH to ubiquinone);GO:0070469(respiratory chain);GO:0008137(NADH dehydrogenase (ubiquinone) activity);GO:0003954(NADH dehydrogenase activity);GO:0032981(mitochondrial respiratory chain complex I assembly);GO:0005783(endoplasmic reticulum)","00190(Oxidative phosphorylation);04723(Retrograde endocannabinoid signaling);05010(Alzheimer's disease);05012(Parkinson's disease);05016(Huntington's disease);04932(Non-alcoholic fatty liver disease (NAFLD))","K03964","NA","NADH:ubiquinone oxidoreductase subunit B8 [Source:HGNC Symbol;Acc:HGNC:7703]",{"v":23.193125,"d":"23.19"},{"v":44.656113,"d":"44.66"},{"v":0.519371782313432,"d":"0.52"},{"v":-0.945160460967962,"d":"-0.95"},{"v":0.084558197688178,"d":"0.08"},{"v":0.361300975802436,"d":"0.36"},"down","no"]
[1380,0,"chr1","+",10032832,10180367,"ENST00000253251",27,4772,"MSTRG.145","UBE4B","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016740(transferase activity);GO:0016567(protein ubiquitination);GO:0004842(ubiquitin-protein transferase activity);GO:0006511(ubiquitin-dependent protein catabolic process);GO:0042787(protein ubiquitination involved in ubiquitin-dependent protein catabolic process);GO:0000151(ubiquitin ligase complex);GO:0034450(ubiquitin-ubiquitin ligase activity);GO:0000209(protein polyubiquitination);GO:0019899(enzyme binding);GO:0009411(response to UV);GO:0008626(granzyme-mediated apoptotic signaling pathway);GO:0030433(ubiquitin-dependent ERAD pathway);GO:0043161(proteasome-mediated ubiquitin-dependent protein catabolic process);GO:0005515(protein binding);GO:0005524(ATP binding);GO:0051117(ATPase binding);GO:0061630(ubiquitin protein ligase activity);GO:0003222(ventricular trabecula myocardium morphogenesis);GO:0006513(protein monoubiquitination);GO:0031175(neuron projection development);GO:0034976(response to endoplasmic reticulum stress);GO:0044257(cellular protein catabolic process);GO:0051865(protein autoubiquitination)","04141(Protein processing in endoplasmic reticulum);04120(Ubiquitin mediated proteolysis)","K10597","EC:2.3.2.27","ubiquitination factor E4B [Source:HGNC Symbol;Acc:HGNC:12500]",{"v":10.588651,"d":"10.59"},{"v":4.256076,"d":"4.26"},{"v":2.48789048879766,"d":"2.49"},{"v":1.31492298275723,"d":"1.31"},{"v":0.0925731566777335,"d":"0.09"},{"v":0.37902702758928,"d":"0.38"},"up","no"]
[105565,0,"chr19","+",54593582,54599720,"ENST00000495417",7,1912,"MSTRG.8424","LILRA1","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0002376(immune system process);GO:0002250(adaptive immune response);GO:0050776(regulation of immune response);GO:0005886(plasma membrane);GO:0007166(cell surface receptor signaling pathway);GO:0004888(transmembrane signaling receptor activity);GO:0006952(defense response);GO:0003823(antigen binding)","04380(Osteoclast differentiation)","K06512","NA","leukocyte immunoglobulin like receptor A1 [Source:HGNC Symbol;Acc:HGNC:6602]",{"v":2.453453,"d":"2.45"},{"v":4.618924,"d":"4.62"},{"v":0.53117414358842,"d":"0.53"},{"v":-0.912743173776055,"d":"-0.91"},{"v":0.0965977940935685,"d":"0.10"},{"v":0.388117187720515,"d":"0.39"},"down","no"]
[36865,0,"chr11","+",128693916,128813266,"ENST00000281428",10,4151,"MSTRG.2969","FLI1","GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0006355(regulation of transcription, DNA-templated);GO:0005634(nucleus);GO:0043565(sequence-specific DNA binding);GO:0005829(cytosol);GO:0006366(transcription from RNA polymerase II promoter);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0016604(nuclear body);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:0000980(RNA polymerase II distal enhancer sequence-specific DNA binding);GO:0001077(transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0003682(chromatin binding);GO:0008015(blood circulation);GO:0009887(animal organ morphogenesis);GO:0035855(megakaryocyte development);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0045893(positive regulation of transcription, DNA-templated);GO:0000981(RNA polymerase II transcription factor activity, sequence-specific DNA binding);GO:0030154(cell differentiation);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0007599(hemostasis)","05202(Transcriptional misregulation in cancers)","K09436","NA","Fli-1 proto-oncogene, ETS transcription factor [Source:HGNC Symbol;Acc:HGNC:3749]",{"v":6.705153,"d":"6.71"},{"v":2.740884,"d":"2.74"},{"v":2.44634687203107,"d":"2.45"},{"v":1.29062898075773,"d":"1.29"},{"v":0.10085111722459,"d":"0.10"},{"v":0.396511406246808,"d":"0.40"},"up","no"]
[38030,0,"chr12","+",6766375,6770952,"ENST00000619580",5,1150,"MSTRG.3067","PTMS","GO:0002376(immune system process);GO:0005634(nucleus);GO:0006260(DNA replication)","NA","NA","NA","parathymosin [Source:HGNC Symbol;Acc:HGNC:9629]",{"v":2.632988,"d":"2.63"},{"v":1.050652,"d":"1.05"},{"v":2.50605148041407,"d":"2.51"},{"v":1.32541605144159,"d":"1.33"},{"v":0.105268382635787,"d":"0.11"},{"v":0.406205981084569,"d":"0.41"},"up","no"]
[75265,0,"chr16","-",70687439,70801161,"ENST00000261776",19,3099,"ENSG00000103043","VAC14","GO:0043550(regulation of lipid kinase activity);GO:0070772(PAS complex);GO:0016020(membrane);GO:0005783(endoplasmic reticulum);GO:0005515(protein binding);GO:0007165(signal transduction);GO:0005768(endosome);GO:0043231(intracellular membrane-bounded organelle);GO:0004872(receptor activity);GO:0010008(endosome membrane);GO:0016032(viral process);GO:0031090(organelle membrane);GO:0006661(phosphatidylinositol biosynthetic process);GO:0000139(Golgi membrane);GO:0031901(early endosome membrane);GO:0031902(late endosome membrane)","05203(Viral carcinogenesis);05166(HTLV-I infection)","K15305","NA","Vac14, PIKFYVE complex component [Source:HGNC Symbol;Acc:HGNC:25507]",{"v":4.585186,"d":"4.59"},{"v":1.909307,"d":"1.91"},{"v":2.40149226918458,"d":"2.40"},{"v":1.26393116430007,"d":"1.26"},{"v":0.110657129956958,"d":"0.11"},{"v":0.415420847578883,"d":"0.42"},"up","no"]
[92518,0,"chr18","+",50915899,50935733,"ENST00000589330",8,5770,"ENSG00000082212","ME2","GO:0046872(metal ion binding);GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0005739(mitochondrion);GO:0003824(catalytic activity);GO:0008152(metabolic process);GO:0051287(NAD binding);GO:0005759(mitochondrial matrix);GO:0004470(malic enzyme activity);GO:0004471(malate dehydrogenase (decarboxylating) (NAD+) activity);GO:0009055(electron carrier activity);GO:0006108(malate metabolic process);GO:0004473(malate dehydrogenase (decarboxylating) (NADP+) activity);GO:0008948(oxaloacetate decarboxylase activity);GO:0006090(pyruvate metabolic process);GO:1902031(regulation of NADP metabolic process)","00620(Pyruvate metabolism)","NA","NA","malic enzyme 2 [Source:HGNC Symbol;Acc:HGNC:6984]",{"v":0.347423,"d":"0.35"},{"v":0.138177,"d":"0.14"},{"v":2.51433306556084,"d":"2.51"},{"v":1.33017577155857,"d":"1.33"},{"v":0.113365540453656,"d":"0.11"},{"v":0.421313329705848,"d":"0.42"},"up","no"]
[165342,0,"chr6","+",33621379,33696569,"ENST00000605930",58,9029,"ENSG00000096433","ITPR3","GO:0005737(cytoplasm);GO:0045177(apical part of cell);GO:0007204(positive regulation of cytosolic calcium ion concentration);GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0055085(transmembrane transport);GO:0005216(ion channel activity);GO:0006811(ion transport);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0006816(calcium ion transport);GO:0070588(calcium ion transmembrane transport);GO:0005262(calcium channel activity);GO:0051209(release of sequestered calcium ion into cytosol);GO:0005509(calcium ion binding);GO:0005220(inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity);GO:0048016(inositol phosphate-mediated signaling);GO:1903779(regulation of cardiac conduction);GO:0030168(platelet activation);GO:0050796(regulation of insulin secretion);GO:0031095(platelet dense tubular network membrane);GO:0043235(receptor complex);GO:0051260(protein homooligomerization);GO:0005887(integral component of plasma membrane);GO:0043025(neuronal cell body);GO:0015278(calcium-release channel activity);GO:0005903(brush border);GO:0007186(G-protein coupled receptor signaling pathway);GO:0051592(response to calcium ion);GO:0070679(inositol 1,4,5 trisphosphate binding);GO:0051291(protein heterooligomerization);GO:0043209(myelin sheath);GO:0005640(nuclear outer membrane);GO:0000822(inositol hexakisphosphate binding);GO:0035091(phosphatidylinositol binding);GO:0043533(inositol 1,3,4,5 tetrakisphosphate binding);GO:0007613(memory);GO:0050913(sensory perception of bitter taste);GO:0050916(sensory perception of sweet taste);GO:0050917(sensory perception of umami taste);GO:0060291(long-term synaptic potentiation);GO:0060402(calcium ion transport into cytosol);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005730(nucleolus)","04371(Apelin signaling pathway);04020(Calcium signaling pathway);04070(Phosphatidylinositol signaling system);04022(cGMP - PKG signaling pathway);04114(Oocyte meiosis);04210(Apoptosis);04218(Cellular senescence);04540(Gap junction);04611(Platelet activation);04621(NOD-like receptor signaling pathway);04911(Insulin secretion);04922(Glucagon signaling pathway);04912(GnRH signaling pathway);04915(Estrogen signaling pathway);04921(Oxytocin signaling pathway);04918(Thyroid hormone synthesis);04924(Renin secretion);04925(Aldosterone synthesis and secretion);04927(Cortisol synthesis and secretion);04270(Vascular smooth muscle contraction);04970(Salivary secretion);04971(Gastric acid secretion);04972(Pancreatic secretion);04724(Glutamatergic synapse);04725(Cholinergic synapse);04728(Dopaminergic synapse);04726(Serotonergic synapse);04720(Long-term potentiation);04730(Long-term depression);04723(Retrograde endocannabinoid signaling);04742(Taste transduction);04750(Inflammatory mediator regulation of TRP channels);04713(Circadian entrainment);05205(Proteoglycans in cancer);05010(Alzheimer's disease);05167(Kaposi's sarcoma-associated herpesvirus infection)","K04960","NA","inositol 1,4,5-trisphosphate receptor type 3 [Source:HGNC Symbol;Acc:HGNC:6182]",{"v":3.903523,"d":"3.90"},{"v":1.653601,"d":"1.65"},{"v":2.3606196416185,"d":"2.36"},{"v":1.23916560388899,"d":"1.24"},{"v":0.11709506604121,"d":"0.12"},{"v":0.427820747197832,"d":"0.43"},"up","no"]
[171235,0,"chr7","-",1152907,1160178,"ENST00000316495",5,860,"MSTRG.13430","ZFAND2A","GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0032436(positive regulation of proteasomal ubiquitin-dependent protein catabolic process);GO:0071243(cellular response to arsenic-containing substance);GO:0000502(proteasome complex)","NA","NA","NA","zinc finger AN1-type containing 2A [Source:HGNC Symbol;Acc:HGNC:28073]",{"v":5.182345,"d":"5.18"},{"v":9.219773,"d":"9.22"},{"v":0.562090303090976,"d":"0.56"},{"v":-0.831126168434291,"d":"-0.83"},{"v":0.12266421765577,"d":"0.12"},{"v":0.439403985728133,"d":"0.44"},"down","no"]
[95513,0,"chr19","-",6467207,6481808,"ENST00000381480",23,2816,"MSTRG.7738","DENND1C","GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0043547(positive regulation of GTPase activity);GO:0031410(cytoplasmic vesicle);GO:0005085(guanyl-nucleotide exchange factor activity);GO:0017112(Rab guanyl-nucleotide exchange factor activity);GO:0061024(membrane organization);GO:0030136(clathrin-coated vesicle)","NA","NA","NA","DENN domain containing 1C [Source:HGNC Symbol;Acc:HGNC:26225]",{"v":18.498152,"d":"18.50"},{"v":8.058634,"d":"8.06"},{"v":2.29544510893534,"d":"2.30"},{"v":1.19877393324234,"d":"1.20"},{"v":0.131139168829445,"d":"0.13"},{"v":0.452786603282783,"d":"0.45"},"up","no"]
[43399,"j","chr12","-",57472259,57478150,"MSTRG.3490.6",16,2279,"MSTRG.3490","ARHGAP9","NA","NA","NA","NA","NA",{"v":1.026253,"d":"1.03"},{"v":1.804565,"d":"1.80"},{"v":0.568698273545148,"d":"0.57"},{"v":-0.814264670325781,"d":"-0.81"},{"v":0.136606221805604,"d":"0.14"},{"v":0.463108431915245,"d":"0.46"},"down","no"]
[180576,0,"chr7","+",156949723,156973182,"ENST00000275820",11,6077,"ENSG00000146909","NOM1","GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005730(nucleolus);GO:0005515(protein binding);GO:0042274(ribosomal small subunit biogenesis);GO:0008150(biological_process);GO:0022008(neurogenesis);GO:0048820(hair follicle maturation)","NA","NA","NA","nucleolar protein with MIF4G domain 1 [Source:HGNC Symbol;Acc:HGNC:13244]",{"v":1.602806,"d":"1.60"},{"v":0.703564,"d":"0.70"},{"v":2.27812395176558,"d":"2.28"},{"v":1.18784624561167,"d":"1.19"},{"v":0.140881897579425,"d":"0.14"},{"v":0.470192442115309,"d":"0.47"},"up","no"]
[135359,0,"chr3","-",44431720,44477670,"ENST00000396077",8,18299,"MSTRG.10860","ZNF445","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0005622(intracellular);GO:0070062(extracellular exosome)","NA","NA","NA","zinc finger protein 445 [Source:HGNC Symbol;Acc:HGNC:21018]",{"v":0.350954,"d":"0.35"},{"v":0.15435,"d":"0.15"},{"v":2.27375445416262,"d":"2.27"},{"v":1.18507646404148,"d":"1.19"},{"v":0.144413594046822,"d":"0.14"},{"v":0.47461488108263,"d":"0.47"},"up","no"]
[205,0,"chr1","+",1013423,1014540,"ENST00000379389",2,711,"MSTRG.1","ISG15","GO:0005737(cytoplasm);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0002376(immune system process);GO:0045087(innate immune response);GO:0042742(defense response to bacterium);GO:0051607(defense response to virus);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0045071(negative regulation of viral genome replication);GO:0016032(viral process);GO:0030501(positive regulation of bone mineralization);GO:0031397(negative regulation of protein ubiquitination);GO:0060337(type I interferon signaling pathway);GO:0019985(translesion synthesis);GO:0032480(negative regulation of type I interferon production);GO:0031386(protein tag);GO:0019941(modification-dependent protein catabolic process);GO:0032020(ISG15-protein conjugation);GO:0032649(regulation of interferon-gamma production);GO:0034340(response to type I interferon);GO:0045648(positive regulation of erythrocyte differentiation)","04622(RIG-I-like receptor signaling pathway);05165(Human papillomavirus infection)","K12159","NA","ISG15 ubiquitin-like modifier [Source:HGNC Symbol;Acc:HGNC:4053]",{"v":20.210918,"d":"20.21"},{"v":34.054207,"d":"34.05"},{"v":0.59349254557594,"d":"0.59"},{"v":-0.75269818553941,"d":"-0.75"},{"v":0.150278795047524,"d":"0.15"},{"v":0.485187925664939,"d":"0.49"},"down","no"]
[1654,"j","chr1","+",11980227,12011754,"MSTRG.164.2",19,2866,"MSTRG.164","MFN2","NA","NA","NA","NA","NA",{"v":1.225559,"d":"1.23"},{"v":2.069905,"d":"2.07"},{"v":0.592084660890234,"d":"0.59"},{"v":-0.756124616475997,"d":"-0.76"},{"v":0.15411305019031,"d":"0.15"},{"v":0.490208814847429,"d":"0.49"},"down","no"]
[41415,0,"chr12","-",49989162,50025461,"ENST00000312377",17,3073,"ENSG00000161800","RACGAP1","GO:0007165(signal transduction);GO:0006810(transport);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0046872(metal ion binding);GO:0005654(nucleoplasm);GO:0035556(intracellular signal transduction);GO:0051301(cell division);GO:0006811(ion transport);GO:0005886(plasma membrane);GO:0043547(positive regulation of GTPase activity);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0007405(neuroblast proliferation);GO:0045995(regulation of embryonic development);GO:0007049(cell cycle);GO:0007275(multicellular organism development);GO:0030154(cell differentiation);GO:0005874(microtubule);GO:0031410(cytoplasmic vesicle);GO:0005096(GTPase activator activity);GO:0007283(spermatogenesis);GO:0008017(microtubule binding);GO:0005819(spindle);GO:0030496(midbody);GO:0008289(lipid binding);GO:0005829(cytosol);GO:0031234(extrinsic component of cytoplasmic side of plasma membrane);GO:0070062(extracellular exosome);GO:0051056(regulation of small GTPase mediated signal transduction);GO:0019901(protein kinase binding);GO:0006890(retrograde vesicle-mediated transport, Golgi to ER);GO:0032154(cleavage furrow);GO:0051233(spindle midzone);GO:0001669(acrosomal vesicle);GO:0043014(alpha-tubulin binding);GO:0005547(phosphatidylinositol-3,4,5-trisphosphate binding);GO:0007018(microtubule-based movement);GO:0019886(antigen processing and presentation of exogenous peptide antigen via MHC class II);GO:0000281(mitotic cytokinesis);GO:0032467(positive regulation of cytokinesis);GO:0048487(beta-tubulin binding);GO:0072686(mitotic spindle);GO:0043015(gamma-tubulin binding);GO:0051256(mitotic spindle midzone assembly);GO:0051988(regulation of attachment of spindle microtubules to kinetochore);GO:0097149(centralspindlin complex);GO:0008272(sulfate transport);GO:0000915(actomyosin contractile ring assembly)","NA","NA","NA","Rac GTPase activating protein 1 [Source:HGNC Symbol;Acc:HGNC:9804]",{"v":1.372581,"d":"1.37"},{"v":0.619492,"d":"0.62"},{"v":2.21565573082461,"d":"2.22"},{"v":1.14773373246253,"d":"1.15"},{"v":0.162108329762747,"d":"0.16"},{"v":0.50165896338557,"d":"0.50"},"up","no"]
[56314,0,"chr14","+",69767172,69771642,"ENST00000556184",7,2443,"MSTRG.4509","SRSF5","GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0006397(mRNA processing);GO:0008380(RNA splicing);GO:0005634(nucleus);GO:0016607(nuclear speck);GO:0005730(nucleolus);GO:0005829(cytosol);GO:0043422(protein kinase B binding);GO:0001889(liver development);GO:0032868(response to insulin);GO:0032869(cellular response to insulin stimulus);GO:0033120(positive regulation of RNA splicing);GO:0051726(regulation of cell cycle);GO:0097421(liver regeneration);GO:0005654(nucleoplasm);GO:0005515(protein binding);GO:0006369(termination of RNA polymerase II transcription);GO:0006405(RNA export from nucleus);GO:0031124(mRNA 3'-end processing);GO:0000398(mRNA splicing, via spliceosome);GO:0006406(mRNA export from nucleus);GO:0006376(mRNA splice site selection)","03040(Spliceosome);05168(Herpes simplex infection)","NA","NA","serine and arginine rich splicing factor 5 [Source:HGNC Symbol;Acc:HGNC:10787]",{"v":10.501951,"d":"10.50"},{"v":4.818564,"d":"4.82"},{"v":2.17947732976048,"d":"2.18"},{"v":1.12398219730869,"d":"1.12"},{"v":0.163262611929404,"d":"0.16"},{"v":0.503215041255303,"d":"0.50"},"up","no"]
[178471,0,"chr7","-",128297685,128343908,"ENST00000223073",19,15507,"ENSG00000106344","RBM28","GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0006397(mRNA processing);GO:0008380(RNA splicing);GO:0005634(nucleus);GO:0005730(nucleolus);GO:0005681(spliceosomal complex)","03008(Ribosome biogenesis in eukaryotes)","K14573","NA","RNA binding motif protein 28 [Source:HGNC Symbol;Acc:HGNC:21863]",{"v":0.973234,"d":"0.97"},{"v":0.452607,"d":"0.45"},{"v":2.15028490500589,"d":"2.15"},{"v":1.10452782437653,"d":"1.10"},{"v":0.173332273942406,"d":"0.17"},{"v":0.517720609324125,"d":"0.52"},"up","no"]
[162825,0,"chr6","+",10747759,10756981,"ENST00000379542",6,975,"MSTRG.12672","TMEM14B","GO:0016020(membrane);GO:0016021(integral component of membrane)","NA","NA","NA","transmembrane protein 14B [Source:HGNC Symbol;Acc:HGNC:21384]",{"v":13.537403,"d":"13.54"},{"v":21.848076,"d":"21.85"},{"v":0.619615338211017,"d":"0.62"},{"v":-0.690555237255877,"d":"-0.69"},{"v":0.178259518365453,"d":"0.18"},{"v":0.52382995029651,"d":"0.52"},"down","no"]
[50887,"j","chr13","-",73685955,74134161,"MSTRG.4019.1",8,10965,"MSTRG.4019","KLF12","NA","NA","NA","NA","NA",{"v":8.791716,"d":"8.79"},{"v":4.16233,"d":"4.16"},{"v":2.11221022840572,"d":"2.11"},{"v":1.07875343336321,"d":"1.08"},{"v":0.182717014997502,"d":"0.18"},{"v":0.529744186480469,"d":"0.53"},"up","no"]
[101949,0,"chr19","+",41860446,41871416,"ENST00000593863",6,526,"MSTRG.8185","RPS19","GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0006412(translation);GO:0030529(intracellular ribonucleoprotein complex);GO:0005622(intracellular);GO:0003735(structural constituent of ribosome);GO:0005840(ribosome);GO:0005829(cytosol);GO:0042803(protein homodimerization activity);GO:0005515(protein binding);GO:0000028(ribosomal small subunit assembly);GO:0022627(cytosolic small ribosomal subunit);GO:0005730(nucleolus);GO:0005925(focal adhesion);GO:0006364(rRNA processing);GO:0042274(ribosomal small subunit biogenesis);GO:0005654(nucleoplasm);GO:0070062(extracellular exosome);GO:0019901(protein kinase binding);GO:0050829(defense response to Gram-negative bacterium);GO:0031012(extracellular matrix);GO:0007219(Notch signaling pathway);GO:0061844(antimicrobial humoral immune response mediated by antimicrobial peptide);GO:0006413(translational initiation);GO:0030490(maturation of SSU-rRNA);GO:0000184(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay);GO:0031640(killing of cells of other organism);GO:0019083(viral transcription);GO:0051262(protein tetramerization);GO:0017134(fibroblast growth factor binding);GO:0006614(SRP-dependent cotranslational protein targeting to membrane);GO:0002548(monocyte chemotaxis);GO:0000462(maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA));GO:0007000(nucleolus organization);GO:0009991(response to extracellular stimulus);GO:0030218(erythrocyte differentiation);GO:0051272(positive regulation of cellular component movement);GO:0060265(positive regulation of respiratory burst involved in inflammatory response);GO:0060266(negative regulation of respiratory burst involved in inflammatory response)","03010(Ribosome)","K02966","NA","ribosomal protein S19 [Source:HGNC Symbol;Acc:HGNC:10402]",{"v":76.994911,"d":"76.99"},{"v":122.440887,"d":"122.44"},{"v":0.628833332447191,"d":"0.63"},{"v":-0.669250402606157,"d":"-0.67"},{"v":0.18710350593995,"d":"0.19"},{"v":0.535261554942857,"d":"0.54"},"down","no"]
[33206,0,"chr11","+",75399515,75404855,"ENST00000529173",5,1373,"MSTRG.2719","RPS3","GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0006412(translation);GO:0006413(translational initiation);GO:0005783(endoplasmic reticulum);GO:0005829(cytosol);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0005743(mitochondrial inner membrane);GO:0016829(lyase activity);GO:0003677(DNA binding);GO:0030529(intracellular ribonucleoprotein complex);GO:0003735(structural constituent of ribosome);GO:0005840(ribosome);GO:0051301(cell division);GO:0005739(mitochondrion);GO:0005886(plasma membrane);GO:0015935(small ribosomal subunit);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0006281(DNA repair);GO:0006974(cellular response to DNA damage stimulus);GO:0007049(cell cycle);GO:0006915(apoptotic process);GO:0022627(cytosolic small ribosomal subunit);GO:0005759(mitochondrial matrix);GO:0051536(iron-sulfur cluster binding);GO:0005730(nucleolus);GO:0005925(focal adhesion);GO:0008017(microtubule binding);GO:0005819(spindle);GO:0007059(chromosome segregation);GO:0003729(mRNA binding);GO:0003906(DNA-(apurinic or apyrimidinic site) lyase activity);GO:0005654(nucleoplasm);GO:0070062(extracellular exosome);GO:0019901(protein kinase binding);GO:0010628(positive regulation of gene expression);GO:0032587(ruffle membrane);GO:0006417(regulation of translation);GO:0031012(extracellular matrix);GO:0017148(negative regulation of translation);GO:0002181(cytoplasmic translation);GO:0042981(regulation of apoptotic process);GO:0019899(enzyme binding);GO:0008134(transcription factor binding);GO:0006979(response to oxidative stress);GO:0015631(tubulin binding);GO:0006364(rRNA processing);GO:0031397(negative regulation of protein ubiquitination);GO:0000184(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay);GO:0051225(spindle assembly);GO:0019083(viral transcription);GO:0045739(positive regulation of DNA repair);GO:0003684(damaged DNA binding);GO:0032357(oxidized purine DNA binding);GO:0019900(kinase binding);GO:0043507(positive regulation of JUN kinase activity);GO:0051018(protein kinase A binding);GO:1901224(positive regulation of NIK/NF-kappaB signaling);GO:0072686(mitotic spindle);GO:0051879(Hsp90 protein binding);GO:0097100(supercoiled DNA binding);GO:0006614(SRP-dependent cotranslational protein targeting to membrane);GO:0070301(cellular response to hydrogen peroxide);GO:0005844(polysome);GO:2001235(positive regulation of apoptotic signaling pathway);GO:0031334(positive regulation of protein complex assembly);GO:0031116(positive regulation of microtubule polymerization);GO:0000977(RNA polymerase II regulatory region sequence-specific DNA binding);GO:0004520(endodeoxyribonuclease activity);GO:0030544(Hsp70 protein binding);GO:0032358(oxidized pyrimidine DNA binding);GO:0032403(protein complex binding);GO:0044390(ubiquitin-like protein conjugating enzyme binding);GO:0070181(small ribosomal subunit rRNA binding);GO:0032079(positive regulation of endodeoxyribonuclease activity);GO:0032743(positive regulation of interleukin-2 production);GO:0042104(positive regulation of activated T cell proliferation);GO:0042769(DNA damage response, detection of DNA damage);GO:0045738(negative regulation of DNA repair);GO:0050862(positive regulation of T cell receptor signaling pathway);GO:0051092(positive regulation of NF-kappaB transcription factor activity);GO:0061481(response to TNF agonist);GO:0071356(cellular response to tumor necrosis factor);GO:1902231(positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage);GO:1902546(positive regulation of DNA N-glycosylase activity);GO:1905053(positive regulation of base-excision repair);GO:2001272(positive regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis);GO:0071159(NF-kappaB complex)","03010(Ribosome)","NA","NA","ribosomal protein S3 [Source:HGNC Symbol;Acc:HGNC:10420]",{"v":0.598733,"d":"0.60"},{"v":0.999458,"d":"1.00"},{"v":0.599057689267583,"d":"0.60"},{"v":-0.739233153621722,"d":"-0.74"},{"v":0.192920092304502,"d":"0.19"},{"v":0.54341005931237,"d":"0.54"},"down","no"]
[98725,0,"chr19","-",18899517,18919363,"ENST00000349893",9,948,"MSTRG.8008","COPE","GO:0006810(transport);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0015031(protein transport);GO:0005794(Golgi apparatus);GO:0005654(nucleoplasm);GO:0005198(structural molecule activity);GO:0005515(protein binding);GO:0000139(Golgi membrane);GO:0006890(retrograde vesicle-mediated transport, Golgi to ER);GO:0031410(cytoplasmic vesicle);GO:0016192(vesicle-mediated transport);GO:0006891(intra-Golgi vesicle-mediated transport);GO:0030663(COPI-coated vesicle membrane);GO:0005789(endoplasmic reticulum membrane);GO:0005829(cytosol);GO:0006888(ER to Golgi vesicle-mediated transport);GO:0030133(transport vesicle);GO:0030126(COPI vesicle coat);GO:0030137(COPI-coated vesicle)","NA","NA","NA","coatomer protein complex subunit epsilon [Source:HGNC Symbol;Acc:HGNC:2234]",{"v":1.034763,"d":"1.03"},{"v":1.687706,"d":"1.69"},{"v":0.613118043071483,"d":"0.61"},{"v":-0.705763233436364,"d":"-0.71"},{"v":0.197984936894596,"d":"0.20"},{"v":0.550358915672377,"d":"0.55"},"down","no"]
[184413,0,"chr8","-",66564697,66612907,"ENST00000524176",15,2148,"MSTRG.14383","MYBL1","GO:0005634(nucleus);GO:0006355(regulation of transcription, DNA-templated);GO:0006366(transcription from RNA polymerase II promoter);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0045893(positive regulation of transcription, DNA-templated);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0030154(cell differentiation);GO:0001077(transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0001135(transcription factor activity, RNA polymerase II transcription factor recruiting);GO:0000278(mitotic cell cycle)","NA","NA","NA","MYB proto-oncogene like 1 [Source:HGNC Symbol;Acc:HGNC:7547]",{"v":4.23841,"d":"4.24"},{"v":2.051802,"d":"2.05"},{"v":2.06570127137024,"d":"2.07"},{"v":1.04663163587112,"d":"1.05"},{"v":0.203324337713072,"d":"0.20"},{"v":0.556869480230625,"d":"0.56"},"up","no"]
[132533,0,"chr22","-",50445000,50475024,"ENST00000380817",41,8008,"MSTRG.10605","SBF1","GO:0005634(nucleus);GO:0016021(integral component of membrane);GO:0043547(positive regulation of GTPase activity);GO:0019208(phosphatase regulator activity);GO:0007283(spermatogenesis);GO:0043087(regulation of GTPase activity);GO:0005085(guanyl-nucleotide exchange factor activity);GO:0005789(endoplasmic reticulum membrane);GO:0005829(cytosol);GO:0017112(Rab guanyl-nucleotide exchange factor activity);GO:0061024(membrane organization);GO:0006661(phosphatidylinositol biosynthetic process);GO:0006470(protein dephosphorylation);GO:0008138(protein tyrosine/serine/threonine phosphatase activity)","NA","NA","NA","SET binding factor 1 [Source:HGNC Symbol;Acc:HGNC:10542]",{"v":9.39721,"d":"9.40"},{"v":4.607232,"d":"4.61"},{"v":2.03966503097738,"d":"2.04"},{"v":1.0283322414969,"d":"1.03"},{"v":0.208930900939654,"d":"0.21"},{"v":0.564503082407673,"d":"0.56"},"up","no"]
[163363,0,"chr6","+",26087319,26098343,"ENST00000357618",6,5286,"MSTRG.12723","HFE","GO:0005615(extracellular space);GO:0010628(positive regulation of gene expression);GO:0048471(perinuclear region of cytoplasm);GO:0030509(BMP signaling pathway);GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0006811(ion transport);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0031410(cytoplasmic vesicle);GO:1990712(HFE-transferrin receptor complex);GO:0006879(cellular iron ion homeostasis);GO:0005769(early endosome);GO:0055037(recycling endosome);GO:0005887(integral component of plasma membrane);GO:0005102(receptor binding);GO:1990459(transferrin receptor binding);GO:0002626(negative regulation of T cell antigen processing and presentation);GO:0098711(iron ion import across plasma membrane);GO:0009897(external side of plasma membrane);GO:0006461(protein complex assembly);GO:0048260(positive regulation of receptor-mediated endocytosis);GO:0032092(positive regulation of protein binding);GO:0032435(negative regulation of proteasomal ubiquitin-dependent protein catabolic process);GO:0002725(negative regulation of T cell cytokine production);GO:0033572(transferrin transport);GO:0045177(apical part of cell);GO:2000273(positive regulation of receptor activity);GO:0010862(positive regulation of pathway-restricted SMAD protein phosphorylation);GO:2000008(regulation of protein localization to cell surface);GO:0090277(positive regulation of peptide hormone secretion);GO:0055072(iron ion homeostasis);GO:0071281(cellular response to iron ion);GO:0045178(basal part of cell);GO:0039706(co-receptor binding);GO:1900121(negative regulation of receptor binding);GO:1900122(positive regulation of receptor binding);GO:1904434(positive regulation of ferrous iron binding);GO:1904437(positive regulation of transferrin receptor binding);GO:1904440(positive regulation of ferrous iron import across plasma membrane);GO:0010039(response to iron ion);GO:0030881(beta-2-microglobulin binding);GO:1904283(negative regulation of antigen processing and presentation of endogenous peptide antigen via MHC class I);GO:2000059(negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process);GO:2000272(negative regulation of receptor activity);GO:2001186(negative regulation of CD8-positive, alpha-beta T cell activation);GO:0006953(acute-phase response);GO:0007565(female pregnancy);GO:0010106(cellular response to iron ion starvation);GO:0042446(hormone biosynthetic process);GO:0060586(multicellular organismal iron ion homeostasis);GO:0097421(liver regeneration);GO:1990641(response to iron ion starvation);GO:1990357(terminal web)","NA","NA","NA","hemochromatosis [Source:HGNC Symbol;Acc:HGNC:4886]",{"v":0.37383,"d":"0.37"},{"v":0.582558,"d":"0.58"},{"v":0.641704345318406,"d":"0.64"},{"v":-0.640019342381513,"d":"-0.64"},{"v":0.217362516217674,"d":"0.22"},{"v":0.571887976454639,"d":"0.57"},"down","no"]
[78930,0,"chr17","+",7583647,7588192,"ENST00000250124",7,1601,"MSTRG.6426","MPDU1","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005789(endoplasmic reticulum membrane);GO:0070062(extracellular exosome);GO:0006457(protein folding);GO:0005515(protein binding);GO:0006488(dolichol-linked oligosaccharide biosynthetic process);GO:0009312(oligosaccharide biosynthetic process)","NA","NA","NA","mannose-P-dolichol utilization defect 1 [Source:HGNC Symbol;Acc:HGNC:7207]",{"v":6.350683,"d":"6.35"},{"v":9.670473,"d":"9.67"},{"v":0.656708622215273,"d":"0.66"},{"v":-0.606674697747612,"d":"-0.61"},{"v":0.22284934942547,"d":"0.22"},{"v":0.577903338074567,"d":"0.58"},"down","no"]
[25725,0,"chr11","-",4384902,4393696,"ENST00000254436",7,1924,"MSTRG.2139","TRIM21","GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0005654(nucleoplasm);GO:0016740(transferase activity);GO:0016567(protein ubiquitination);GO:0003677(DNA binding);GO:0030529(intracellular ribonucleoprotein complex);GO:0005622(intracellular);GO:0004842(ubiquitin-protein transferase activity);GO:0005515(protein binding);GO:0007049(cell cycle);GO:0031410(cytoplasmic vesicle);GO:0045087(innate immune response);GO:0042802(identical protein binding);GO:0000932(P-body);GO:0005829(cytosol);GO:0010508(positive regulation of autophagy);GO:0031648(protein destabilization);GO:0000209(protein polyubiquitination);GO:0032088(negative regulation of NF-kappaB transcription factor activity);GO:0005776(autophagosome);GO:0051091(positive regulation of sequence-specific DNA binding transcription factor activity);GO:0060333(interferon-gamma-mediated signaling pathway);GO:0045787(positive regulation of cell cycle);GO:0034341(response to interferon-gamma);GO:0051865(protein autoubiquitination);GO:0006513(protein monoubiquitination);GO:0032897(negative regulation of viral transcription);GO:1902187(negative regulation of viral release from host cell);GO:0032479(regulation of type I interferon production);GO:0070206(protein trimerization);GO:0019005(SCF ubiquitin ligase complex);GO:0046598(positive regulation of viral entry into host cell);GO:0090086(negative regulation of protein deubiquitination)","05322(Systemic lupus erythematosus)","K10651","EC:2.3.2.27","tripartite motif containing 21 [Source:HGNC Symbol;Acc:HGNC:11312]",{"v":24.621229,"d":"24.62"},{"v":37.171047,"d":"37.17"},{"v":0.662376526547665,"d":"0.66"},{"v":-0.594276547704302,"d":"-0.59"},{"v":0.227388454961748,"d":"0.23"},{"v":0.582754559571329,"d":"0.58"},"down","no"]
[17795,"j","chr1","+",247857139,247897326,"MSTRG.1507.1",6,2749,"MSTRG.1507","TRIM58","NA","NA","NA","NA","NA",{"v":12.42335,"d":"12.42"},{"v":6.26345,"d":"6.26"},{"v":1.98346757777263,"d":"1.98"},{"v":0.988024815043599,"d":"0.99"},{"v":0.232802708696835,"d":"0.23"},{"v":0.589619864289387,"d":"0.59"},"up","no"]
[2400,0,"chr1","-",20742682,20775005,"ENST00000375003",9,4822,"MSTRG.216","HP1BP3","GO:0005634(nucleus);GO:0016607(nuclear speck);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0006334(nucleosome assembly);GO:0000786(nucleosome);GO:0005694(chromosome);GO:0005515(protein binding);GO:0003682(chromatin binding);GO:0070828(heterochromatin organization);GO:0042127(regulation of cell proliferation);GO:0071456(cellular response to hypoxia);GO:0031491(nucleosome binding);GO:0097298(regulation of nucleus size)","NA","NA","NA","heterochromatin protein 1 binding protein 3 [Source:HGNC Symbol;Acc:HGNC:24973]",{"v":2.489057,"d":"2.49"},{"v":1.257718,"d":"1.26"},{"v":1.9790263000132,"d":"1.98"},{"v":0.984790785021351,"d":"0.98"},{"v":0.238595330036768,"d":"0.24"},{"v":0.59603409248909,"d":"0.60"},"up","no"]
[174519,0,"chr7","-",64990809,65006653,"ENST00000394323",2,2719,"MSTRG.13650","ERV3-1","GO:0003674(molecular_function);GO:0008150(biological_process);GO:0070062(extracellular exosome);GO:0019031(viral envelope);GO:0019012(virion)","NA","NA","NA","endogenous retrovirus group 3 member 1, envelope [Source:HGNC Symbol;Acc:HGNC:3454]",{"v":2.272421,"d":"2.27"},{"v":1.148856,"d":"1.15"},{"v":1.97798592686986,"d":"1.98"},{"v":0.984032161533177,"d":"0.98"},{"v":0.243635867690025,"d":"0.24"},{"v":0.601655628335231,"d":"0.60"},"up","no"]
[160073,0,"chr5","+",150601080,150654232,"ENST00000394243",3,7063,"ENSG00000171992","SYNPO","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0003779(actin binding);GO:0005886(plasma membrane);GO:0005856(cytoskeleton);GO:0042995(cell projection);GO:0030054(cell junction);GO:0045202(synapse);GO:0045211(postsynaptic membrane);GO:0005634(nucleus);GO:0005923(bicellular tight junction);GO:0005515(protein binding);GO:0043204(perikaryon);GO:0030018(Z disc);GO:0014069(postsynaptic density);GO:0015629(actin cytoskeleton);GO:0043197(dendritic spine);GO:0032233(positive regulation of actin filament bundle assembly);GO:0008542(visual learning);GO:0048169(regulation of long-term neuronal synaptic plasticity);GO:0098886(modification of dendritic spine);GO:1905355(spine apparatus assembly);GO:0097444(spine apparatus)","04530(Tight junction)","K21112","NA","synaptopodin [Source:HGNC Symbol;Acc:HGNC:30672]",{"v":0.412751,"d":"0.41"},{"v":0.206452,"d":"0.21"},{"v":1.99925890763955,"d":"2.00"},{"v":0.999465315794654,"d":"1.00"},{"v":0.248885901123803,"d":"0.25"},{"v":0.606446769047877,"d":"0.61"},"up","no"]
[120725,0,"chr2","-",238170401,238203729,"ENST00000254654",12,1490,"ENSG00000132323","ILKAP","GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0016787(hydrolase activity);GO:0003824(catalytic activity);GO:0006470(protein dephosphorylation);GO:0004721(phosphoprotein phosphatase activity);GO:0005515(protein binding);GO:0004722(protein serine/threonine phosphatase activity);GO:0043169(cation binding);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0007229(integrin-mediated signaling pathway)","NA","NA","NA","ILK associated serine/threonine phosphatase [Source:HGNC Symbol;Acc:HGNC:15566]",{"v":4.691275,"d":"4.69"},{"v":6.840326,"d":"6.84"},{"v":0.685826231088986,"d":"0.69"},{"v":-0.544085010184709,"d":"-0.54"},{"v":0.26108746574144,"d":"0.26"},{"v":0.620248958327339,"d":"0.62"},"down","no"]
[184708,0,"chr8","-",73291042,73294438,"ENST00000396465",6,1308,"MSTRG.14403","RPL7","GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0006412(translation);GO:0030529(intracellular ribonucleoprotein complex);GO:0005840(ribosome);GO:0005515(protein binding);GO:0003735(structural constituent of ribosome);GO:0005730(nucleolus);GO:0005925(focal adhesion);GO:0006364(rRNA processing);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0042273(ribosomal large subunit biogenesis);GO:0002181(cytoplasmic translation);GO:0006413(translational initiation);GO:0003677(DNA binding);GO:0042803(protein homodimerization activity);GO:0000184(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay);GO:0019083(viral transcription);GO:0006614(SRP-dependent cotranslational protein targeting to membrane);GO:0022625(cytosolic large ribosomal subunit);GO:0003729(mRNA binding);GO:0000463(maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA));GO:0005844(polysome)","03010(Ribosome)","K02937","NA","ribosomal protein L7 [Source:HGNC Symbol;Acc:HGNC:10363]",{"v":3.970989,"d":"3.97"},{"v":5.768596,"d":"5.77"},{"v":0.688380500211837,"d":"0.69"},{"v":-0.538721864223554,"d":"-0.54"},{"v":0.265714181464108,"d":"0.27"},{"v":0.624608246948417,"d":"0.62"},"down","no"]
[69162,0,"chr16","+",4693707,4695859,"ENST00000586536",3,1406,"MSTRG.5608","NUDT16L1","GO:0003723(RNA binding);GO:0005634(nucleus);GO:0016787(hydrolase activity);GO:0005515(protein binding);GO:0030515(snoRNA binding);GO:2001033(negative regulation of double-strand break repair via nonhomologous end joining)","05205(Proteoglycans in cancer)","K16867","NA","nudix hydrolase 16 like 1 [Source:HGNC Symbol;Acc:HGNC:28154]",{"v":3.359667,"d":"3.36"},{"v":1.737213,"d":"1.74"},{"v":1.9339407430177,"d":"1.93"},{"v":0.95154359054163,"d":"0.95"},{"v":0.268896250148206,"d":"0.27"},{"v":0.627593359190212,"d":"0.63"},"up","no"]
[22743,0,"chr10","-",98429151,98446913,"ENST00000338546",10,1580,"MSTRG.1901","HPS1","GO:0043547(positive regulation of GTPase activity);GO:0005515(protein binding);GO:0050896(response to stimulus);GO:0005085(guanyl-nucleotide exchange factor activity);GO:0005829(cytosol);GO:0061024(membrane organization);GO:0007601(visual perception);GO:0005887(integral component of plasma membrane);GO:0005764(lysosome);GO:0005737(cytoplasm);GO:0031410(cytoplasmic vesicle);GO:0046983(protein dimerization activity);GO:0007040(lysosome organization);GO:1903232(melanosome assembly);GO:0031085(BLOC-3 complex)","NA","NA","NA","HPS1, biogenesis of lysosomal organelles complex 3 subunit 1 [Source:HGNC Symbol;Acc:HGNC:5163]",{"v":5.883995,"d":"5.88"},{"v":8.433485,"d":"8.43"},{"v":0.697694369528137,"d":"0.70"},{"v":-0.519332903909114,"d":"-0.52"},{"v":0.276676552049425,"d":"0.28"},{"v":0.635278148282927,"d":"0.64"},"down","no"]
[190094,0,"chr9","+",35792154,35809732,"ENST00000342694",22,3686,"ENSG00000159899","NPR2","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0035556(intracellular signal transduction);GO:0016829(lyase activity);GO:0005525(GTP binding);GO:0005886(plasma membrane);GO:0005887(integral component of plasma membrane);GO:0016849(phosphorus-oxygen lyase activity);GO:0009190(cyclic nucleotide biosynthetic process);GO:0004383(guanylate cyclase activity);GO:0006182(cGMP biosynthetic process);GO:0001503(ossification);GO:1903779(regulation of cardiac conduction);GO:0005515(protein binding);GO:0008074(guanylate cyclase complex, soluble);GO:0017046(peptide hormone binding);GO:0008217(regulation of blood pressure);GO:0007168(receptor guanylyl cyclase signaling pathway);GO:0042562(hormone binding);GO:0016941(natriuretic peptide receptor activity);GO:0042802(identical protein binding);GO:0044702(single organism reproductive process);GO:0051447(negative regulation of meiotic cell cycle);GO:0060348(bone development);GO:0097011(cellular response to granulocyte macrophage colony-stimulating factor stimulus);GO:1900194(negative regulation of oocyte maturation);GO:0005622(intracellular)","00230(Purine metabolism);04022(cGMP - PKG signaling pathway);04921(Oxytocin signaling pathway);04270(Vascular smooth muscle contraction)","K12324","EC:4.6.1.2","natriuretic peptide receptor 2 [Source:HGNC Symbol;Acc:HGNC:7944]",{"v":0.227245,"d":"0.23"},{"v":0.338415,"d":"0.34"},{"v":0.671498012794941,"d":"0.67"},{"v":-0.574544964683827,"d":"-0.57"},{"v":0.281199886813725,"d":"0.28"},{"v":0.63891319724624,"d":"0.64"},"down","no"]
[127592,0,"chr21","-",43092956,43107524,"ENST00000475639",7,4694,"MSTRG.10068","U2AF1","GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0006397(mRNA processing);GO:0008380(RNA splicing);GO:0005634(nucleus);GO:0016607(nuclear speck);GO:0046872(metal ion binding);GO:0005654(nucleoplasm);GO:0005515(protein binding);GO:0005681(spliceosomal complex);GO:0000398(mRNA splicing, via spliceosome);GO:0089701(U2AF);GO:0030628(pre-mRNA 3'-splice site binding);GO:0006369(termination of RNA polymerase II transcription);GO:0006405(RNA export from nucleus);GO:0031124(mRNA 3'-end processing);GO:1903146(regulation of mitophagy);GO:1903955(positive regulation of protein targeting to mitochondrion);GO:0006406(mRNA export from nucleus);GO:0071013(catalytic step 2 spliceosome);GO:0015030(Cajal body)","03040(Spliceosome);05131(Shigellosis)","NA","NA","U2 small nuclear RNA auxiliary factor 1 [Source:HGNC Symbol;Acc:HGNC:12453]",{"v":0.628641,"d":"0.63"},{"v":0.329659,"d":"0.33"},{"v":1.90694323528252,"d":"1.91"},{"v":0.931261899028077,"d":"0.93"},{"v":0.286045738098012,"d":"0.29"},{"v":0.641972673866786,"d":"0.64"},"up","no"]
[71060,0,"chr16","-",27224991,27268794,"ENST00000361439",8,1067,"MSTRG.5763","NSMCE1","GO:0005634(nucleus);GO:0043231(intracellular membrane-bounded organelle);GO:0046872(metal ion binding);GO:0005654(nucleoplasm);GO:0035556(intracellular signal transduction);GO:0016567(protein ubiquitination);GO:0005694(chromosome);GO:0006281(DNA repair);GO:0016874(ligase activity);GO:0005515(protein binding);GO:0006310(DNA recombination);GO:0006974(cellular response to DNA damage stimulus);GO:0030915(Smc5-Smc6 complex);GO:0000781(chromosome, telomeric region);GO:0006301(postreplication repair);GO:0004842(ubiquitin-protein transferase activity);GO:0046983(protein dimerization activity);GO:0000724(double-strand break repair via homologous recombination);GO:2001022(positive regulation of response to DNA damage stimulus)","NA","NA","NA","NSE1 homolog, SMC5-SMC6 complex component [Source:HGNC Symbol;Acc:HGNC:29897]",{"v":10.612561,"d":"10.61"},{"v":15.007683,"d":"15.01"},{"v":0.707141868601569,"d":"0.71"},{"v":-0.499928413663797,"d":"-0.50"},{"v":0.290626673187038,"d":"0.29"},{"v":0.645518083850612,"d":"0.65"},"down","no"]
[123743,0,"chr20","+",41028818,41124487,"ENST00000361337",21,3738,"MSTRG.9747","TOP1","GO:0003723(RNA binding);GO:0005634(nucleus);GO:0016853(isomerase activity);GO:0016310(phosphorylation);GO:0003677(DNA binding);GO:0001650(fibrillar center);GO:0005515(protein binding);GO:0005694(chromosome);GO:0003916(DNA topoisomerase activity);GO:0003917(DNA topoisomerase type I activity);GO:0006265(DNA topological change);GO:0007623(circadian rhythm);GO:0048511(rhythmic process);GO:0005654(nucleoplasm);GO:0005730(nucleolus);GO:0000932(P-body);GO:0003682(chromatin binding);GO:0016032(viral process);GO:0006338(chromatin remodeling);GO:0019904(protein domain specific binding);GO:0032922(circadian regulation of gene expression);GO:0012501(programmed cell death);GO:0001046(core promoter sequence-specific DNA binding);GO:0016925(protein sumoylation);GO:0000228(nuclear chromosome);GO:0007059(chromosome segregation);GO:0032993(protein-DNA complex);GO:0031298(replication fork protection complex);GO:0042493(response to drug);GO:0005524(ATP binding);GO:0003690(double-stranded DNA binding);GO:0003697(single-stranded DNA binding);GO:0004674(protein serine/threonine kinase activity);GO:0097100(supercoiled DNA binding);GO:0006260(DNA replication);GO:0018105(peptidyl-serine phosphorylation);GO:0040016(embryonic cleavage);GO:0005737(cytoplasm);GO:0009330(DNA topoisomerase complex (ATP-hydrolyzing));GO:0043204(perikaryon)","NA","NA","NA","topoisomerase (DNA) I [Source:HGNC Symbol;Acc:HGNC:11986]",{"v":22.13793,"d":"22.14"},{"v":11.971897,"d":"11.97"},{"v":1.84915807411307,"d":"1.85"},{"v":0.88686855789044,"d":"0.89"},{"v":0.296312645573324,"d":"0.30"},{"v":0.650264459421642,"d":"0.65"},"up","no"]
[112971,"j","chr2","+",101697931,101891869,"MSTRG.9017.8",30,4430,"MSTRG.9017","MAP4K4","NA","NA","NA","NA","NA",{"v":10.322211,"d":"10.32"},{"v":5.642615,"d":"5.64"},{"v":1.82933108142235,"d":"1.83"},{"v":0.871316204829583,"d":"0.87"},{"v":0.307748205720009,"d":"0.31"},{"v":0.660273211205323,"d":"0.66"},"up","no"]
[168391,0,"chr6","-",110424687,110476641,"ENST00000368919",8,1987,"ENSG00000004809","SLC22A16","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0055085(transmembrane transport);GO:0022857(transmembrane transporter activity);GO:0006810(transport);GO:0006811(ion transport);GO:0005886(plasma membrane);GO:0007275(multicellular organism development);GO:0030154(cell differentiation);GO:0007283(spermatogenesis);GO:0015711(organic anion transport);GO:0008514(organic anion transmembrane transporter activity);GO:0007338(single fertilization);GO:0030317(flagellated sperm motility);GO:0015101(organic cation transmembrane transporter activity);GO:0015695(organic cation transport);GO:1902603(carnitine transmembrane transport);GO:0015226(carnitine transmembrane transporter activity);GO:0005275(amine transmembrane transporter activity);GO:0015837(amine transport);GO:0015879(carnitine transport);GO:0046717(acid secretion)","NA","NA","NA","solute carrier family 22 member 16 [Source:HGNC Symbol;Acc:HGNC:20302]",{"v":0.611688,"d":"0.61"},{"v":0.875429,"d":"0.88"},{"v":0.698729422945779,"d":"0.70"},{"v":-0.517194202586201,"d":"-0.52"},{"v":0.312746747117009,"d":"0.31"},{"v":0.664444130550932,"d":"0.66"},"down","no"]
[125299,0,"chr20","+",62796453,62801738,"ENST00000370487",5,2781,"MSTRG.9876","MRGBP","GO:0005634(nucleus);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0016569(covalent chromatin modification);GO:0005515(protein binding);GO:0005654(nucleoplasm);GO:0040008(regulation of growth);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0035267(NuA4 histone acetyltransferase complex);GO:0016573(histone acetylation);GO:0043189(H4/H2A histone acetyltransferase complex)","NA","NA","NA","MRG domain binding protein [Source:HGNC Symbol;Acc:HGNC:15866]",{"v":2.584735,"d":"2.58"},{"v":1.422122,"d":"1.42"},{"v":1.81751987522871,"d":"1.82"},{"v":0.861971140616459,"d":"0.86"},{"v":0.319334951309245,"d":"0.32"},{"v":0.670664404214322,"d":"0.67"},"up","no"]
[44151,0,"chr12","+",68610908,68659401,"ENST00000537460",9,1072,"MSTRG.3540","RAP1B","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005525(GTP binding);GO:0000166(nucleotide binding);GO:0007165(signal transduction);GO:0003924(GTPase activity);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0030054(cell junction);GO:0007264(small GTPase mediated signal transduction);GO:0008283(cell proliferation);GO:0009743(response to carbohydrate);GO:0035690(cellular response to drug);GO:0045955(negative regulation of calcium ion-dependent exocytosis);GO:0070374(positive regulation of ERK1 and ERK2 cascade);GO:0071407(cellular response to organic cyclic compound);GO:0097211(cellular response to gonadotropin-releasing hormone);GO:2000301(negative regulation of synaptic vesicle exocytosis);GO:2000114(regulation of establishment of cell polarity);GO:0070062(extracellular exosome);GO:0043312(neutrophil degranulation);GO:0035722(interleukin-12-mediated signaling pathway);GO:0019003(GDP binding);GO:0032403(protein complex binding);GO:0061028(establishment of endothelial barrier);GO:0035577(azurophil granule membrane);GO:0005911(cell-cell junction);GO:0005811(lipid particle);GO:0005622(intracellular);GO:0071320(cellular response to cAMP);GO:0032486(Rap protein signal transduction);GO:1901888(regulation of cell junction assembly)","04014(Ras signaling pathway);04015(Rap1 signaling pathway);04010(MAPK signaling pathway);04024(cAMP signaling pathway);04510(Focal adhesion);04611(Platelet activation);04670(Leukocyte transendothelial migration);04062(Chemokine signaling pathway);04972(Pancreatic secretion);04720(Long-term potentiation);04722(Neurotrophin signaling pathway);05211(Renal cell carcinoma)","NA","NA","RAP1B, member of RAS oncogene family [Source:HGNC Symbol;Acc:HGNC:9857]",{"v":17.993853,"d":"17.99"},{"v":9.955117,"d":"9.96"},{"v":1.80749789279222,"d":"1.81"},{"v":0.853993965262154,"d":"0.85"},{"v":0.323273331951948,"d":"0.32"},{"v":0.674137618248243,"d":"0.67"},"up","no"]
[4862,0,"chr1","-",42176545,42335232,"ENST00000361346",13,5225,"MSTRG.469","FOXJ3","GO:0005634(nucleus);GO:0006355(regulation of transcription, DNA-templated);GO:0006366(transcription from RNA polymerase II promoter);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0043565(sequence-specific DNA binding);GO:0000981(RNA polymerase II transcription factor activity, sequence-specific DNA binding);GO:0001228(transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0009653(anatomical structure morphogenesis);GO:0030154(cell differentiation)","NA","NA","NA","forkhead box J3 [Source:HGNC Symbol;Acc:HGNC:29178]",{"v":6.656291,"d":"6.66"},{"v":3.720919,"d":"3.72"},{"v":1.78888360644239,"d":"1.79"},{"v":0.839059521615028,"d":"0.84"},{"v":0.332174492993939,"d":"0.33"},{"v":0.683200173304654,"d":"0.68"},"up","no"]
[98660,0,"chr19","+",18571860,18577550,"ENST00000442744",5,2845,"MSTRG.8003","UBA52","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005783(endoplasmic reticulum);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0030529(intracellular ribonucleoprotein complex);GO:0005765(lysosomal membrane);GO:0003735(structural constituent of ribosome);GO:0006412(translation);GO:0005840(ribosome);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0044322(endoplasmic reticulum quality control compartment);GO:0005615(extracellular space);GO:0038095(Fc-epsilon receptor signaling pathway);GO:0016567(protein ubiquitination);GO:0005789(endoplasmic reticulum membrane);GO:0006977(DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest);GO:0070062(extracellular exosome);GO:0034220(ion transmembrane transport);GO:0044267(cellular protein metabolic process);GO:0061024(membrane organization);GO:0016197(endosomal transport);GO:0019058(viral life cycle);GO:0075733(intracellular transport of virus);GO:0010008(endosome membrane);GO:0043657(host cell);GO:0000165(MAPK cascade);GO:0000209(protein polyubiquitination);GO:0002223(stimulatory C-type lectin receptor signaling pathway);GO:0010972(negative regulation of G2/M transition of mitotic cell cycle);GO:0016579(protein deubiquitination);GO:0031145(anaphase-promoting complex-dependent catabolic process);GO:0031146(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process);GO:0033209(tumor necrosis factor-mediated signaling pathway);GO:0038061(NIK/NF-kappaB signaling);GO:0043161(proteasome-mediated ubiquitin-dependent protein catabolic process);GO:0043488(regulation of mRNA stability);GO:0050852(T cell receptor signaling pathway);GO:0051437(positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition);GO:0055085(transmembrane transport);GO:0060071(Wnt signaling pathway, planar cell polarity pathway);GO:0061418(regulation of transcription from RNA polymerase II promoter in response to hypoxia);GO:0090090(negative regulation of canonical Wnt signaling pathway);GO:0090263(positive regulation of canonical Wnt signaling pathway);GO:1902036(regulation of hematopoietic stem cell differentiation);GO:0045087(innate immune response);GO:0000086(G2/M transition of mitotic cell cycle);GO:0036297(interstrand cross-link repair);GO:0006457(protein folding);GO:0002755(MyD88-dependent toll-like receptor signaling pathway);GO:0002756(MyD88-independent toll-like receptor signaling pathway);GO:0007249(I-kappaB kinase/NF-kappaB signaling);GO:0035666(TRIF-dependent toll-like receptor signaling pathway);GO:0051436(negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle);GO:1904380(endoplasmic reticulum mannose trimming);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:1901796(regulation of signal transduction by p53 class mediator);GO:0031982(vesicle);GO:0006413(translational initiation);GO:0006464(cellular protein modification process);GO:0030666(endocytic vesicle membrane);GO:0005741(mitochondrial outer membrane);GO:0006364(rRNA processing);GO:0007219(Notch signaling pathway);GO:0016055(Wnt signaling pathway);GO:0042787(protein ubiquitination involved in ubiquitin-dependent protein catabolic process);GO:0038128(ERBB2 signaling pathway);GO:0007254(JNK cascade);GO:0043065(positive regulation of apoptotic process);GO:0010803(regulation of tumor necrosis factor-mediated signaling pathway);GO:0043066(negative regulation of apoptotic process);GO:0043123(positive regulation of I-kappaB kinase/NF-kappaB signaling);GO:0051092(positive regulation of NF-kappaB transcription factor activity);GO:0051403(stress-activated MAPK cascade);GO:0070423(nucleotide-binding oligomerization domain containing signaling pathway);GO:0019985(translesion synthesis);GO:0032480(negative regulation of type I interferon production);GO:0042059(negative regulation of epidermal growth factor receptor signaling pathway);GO:0030512(negative regulation of transforming growth factor beta receptor signaling pathway);GO:0000184(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay);GO:0005978(glycogen biosynthetic process);GO:0019083(viral transcription);GO:0006283(transcription-coupled nucleotide-excision repair);GO:0008543(fibroblast growth factor receptor signaling pathway);GO:0000187(activation of MAPK activity);GO:0016236(macroautophagy);GO:0042276(error-prone translesion synthesis);GO:0035635(entry of bacterium into host cell);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0006614(SRP-dependent cotranslational protein targeting to membrane);GO:0042769(DNA damage response, detection of DNA damage);GO:0007179(transforming growth factor beta receptor signaling pathway);GO:0006879(cellular iron ion homeostasis);GO:0006296(nucleotide-excision repair, DNA incision, 5'-to lesion);GO:0033683(nucleotide-excision repair, DNA incision);GO:0070911(global genome nucleotide-excision repair);GO:0000715(nucleotide-excision repair, DNA damage recognition);GO:0000717(nucleotide-excision repair, DNA duplex unwinding);GO:0006294(nucleotide-excision repair, preincision complex assembly);GO:0006297(nucleotide-excision repair, DNA gap filling);GO:0019068(virion assembly);GO:0032479(regulation of type I interferon production);GO:0045742(positive regulation of epidermal growth factor receptor signaling pathway);GO:0060544(regulation of necroptotic process);GO:0070987(error-free translesion synthesis)","03010(Ribosome)","K02927","NA","ubiquitin A-52 residue ribosomal protein fusion product 1 [Source:HGNC Symbol;Acc:HGNC:12458]",{"v":112.763687,"d":"112.76"},{"v":151.830872,"d":"151.83"},{"v":0.742692744331996,"d":"0.74"},{"v":-0.429162610783866,"d":"-0.43"},{"v":0.337270664466576,"d":"0.34"},{"v":0.687075408900568,"d":"0.69"},"down","no"]
[137406,0,"chr3","-",56728987,56916471,"ENST00000496106",11,1994,"MSTRG.11009","ARHGEF3","GO:0005737(cytoplasm);GO:0035556(intracellular signal transduction);GO:0005089(Rho guanyl-nucleotide exchange factor activity);GO:0035023(regulation of Rho protein signal transduction);GO:0043547(positive regulation of GTPase activity);GO:0005515(protein binding);GO:0005085(guanyl-nucleotide exchange factor activity);GO:0005829(cytosol);GO:0051056(regulation of small GTPase mediated signal transduction);GO:0007266(Rho protein signal transduction);GO:0043065(positive regulation of apoptotic process);GO:0005622(intracellular)","NA","NA","NA","Rho guanine nucleotide exchange factor 3 [Source:HGNC Symbol;Acc:HGNC:683]",{"v":4.117724,"d":"4.12"},{"v":5.542308,"d":"5.54"},{"v":0.742961957365054,"d":"0.74"},{"v":-0.428639754010292,"d":"-0.43"},{"v":0.343037014911564,"d":"0.34"},{"v":0.692290333673327,"d":"0.69"},"down","no"]
[193661,0,"chr9","-",127935341,127937818,"ENST00000470181",3,928,"MSTRG.14988","DPM2","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0050790(regulation of catalytic activity);GO:0006486(protein glycosylation);GO:0030234(enzyme regulator activity);GO:0030176(integral component of endoplasmic reticulum membrane);GO:0006506(GPI anchor biosynthetic process);GO:0005515(protein binding);GO:0031647(regulation of protein stability);GO:0004582(dolichyl-phosphate beta-D-mannosyltransferase activity);GO:0018279(protein N-linked glycosylation via asparagine);GO:0035269(protein O-linked mannosylation);GO:0033185(dolichol-phosphate-mannose synthase complex);GO:0016254(preassembly of GPI anchor in ER membrane);GO:0019348(dolichol metabolic process);GO:0000506(glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex)","00510(N-Glycan biosynthesis);00563(Glycosylphosphatidylinositol(GPI)-anchor biosynthesis)","NA","NA","dolichyl-phosphate mannosyltransferase subunit 2, regulatory [Source:HGNC Symbol;Acc:HGNC:3006]",{"v":3.455882,"d":"3.46"},{"v":4.636153,"d":"4.64"},{"v":0.745420179187356,"d":"0.75"},{"v":-0.423874220253823,"d":"-0.42"},{"v":0.356869807842512,"d":"0.36"},{"v":0.704342684778339,"d":"0.70"},"down","no"]
[137946,0,"chr3","+",69084944,69106066,"ENST00000273258",3,2101,"MSTRG.11046","ARL6IP5","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005886(plasma membrane);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0002037(negative regulation of L-glutamate transport);GO:0015813(L-glutamate transport);GO:0003674(molecular_function);GO:0070062(extracellular exosome);GO:0043065(positive regulation of apoptotic process);GO:0032874(positive regulation of stress-activated MAPK cascade);GO:0043280(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process);GO:0008631(intrinsic apoptotic signaling pathway in response to oxidative stress);GO:0010917(negative regulation of mitochondrial membrane potential)","NA","NA","NA","ADP ribosylation factor like GTPase 6 interacting protein 5 [Source:HGNC Symbol;Acc:HGNC:16937]",{"v":61.118835,"d":"61.12"},{"v":80.451668,"d":"80.45"},{"v":0.759696306110148,"d":"0.76"},{"v":-0.396505288477801,"d":"-0.40"},{"v":0.362937235770134,"d":"0.36"},{"v":0.70980450893649,"d":"0.71"},"down","no"]
[122764,0,"chr20","+",31514428,31569567,"ENST00000340852",12,1606,"MSTRG.9638","HM13","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005783(endoplasmic reticulum);GO:0016787(hydrolase activity);GO:0005789(endoplasmic reticulum membrane);GO:0042803(protein homodimerization activity);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0008233(peptidase activity);GO:0006508(proteolysis);GO:0004190(aspartic-type endopeptidase activity);GO:0031625(ubiquitin protein ligase binding);GO:0005765(lysosomal membrane);GO:0009986(cell surface);GO:0005791(rough endoplasmic reticulum);GO:0033619(membrane protein proteolysis);GO:0042500(aspartic endopeptidase activity, intramembrane cleaving);GO:0036513(Derlin-1 retrotranslocation complex);GO:0030660(Golgi-associated vesicle membrane);GO:0071458(integral component of cytoplasmic side of endoplasmic reticulum membrane);GO:0071556(integral component of lumenal side of endoplasmic reticulum membrane);GO:0051289(protein homotetramerization);GO:1904211(membrane protein proteolysis involved in retrograde protein transport, ER to cytosol)","NA","NA","NA","histocompatibility minor 13 [Source:HGNC Symbol;Acc:HGNC:16435]",{"v":25.326982,"d":"25.33"},{"v":14.640945,"d":"14.64"},{"v":1.72987344737652,"d":"1.73"},{"v":0.790666498254747,"d":"0.79"},{"v":0.369441742866057,"d":"0.37"},{"v":0.715901163679102,"d":"0.72"},"up","no"]
[179814,0,"chr7","-",144451941,144836053,"ENST00000360057",9,2439,"ENSG00000196511","TPK1","GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0004788(thiamine diphosphokinase activity);GO:0030975(thiamine binding);GO:0006772(thiamine metabolic process);GO:0009229(thiamine diphosphate biosynthetic process);GO:0005829(cytosol);GO:0042723(thiamine-containing compound metabolic process)","00730(Thiamine metabolism)","K00949","EC:2.7.6.2","thiamin pyrophosphokinase 1 [Source:HGNC Symbol;Acc:HGNC:17358]",{"v":2.184009,"d":"2.18"},{"v":2.857745,"d":"2.86"},{"v":0.76424208598038,"d":"0.76"},{"v":-0.387898387357683,"d":"-0.39"},{"v":0.376684393706376,"d":"0.38"},{"v":0.722410426697206,"d":"0.72"},"down","no"]
[63493,0,"chr15","-",64165517,64356259,"ENST00000303052",12,8179,"MSTRG.5192","CSNK1G1","GO:0005737(cytoplasm);GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0005829(cytosol);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0005515(protein binding);GO:0016055(Wnt signaling pathway);GO:0005634(nucleus);GO:0008360(regulation of cell shape);GO:0006897(endocytosis);GO:0018105(peptidyl-serine phosphorylation);GO:0016020(membrane);GO:0016021(integral component of membrane)","04340(Hedgehog signaling pathway)","K08958","EC:2.7.11.1","casein kinase 1 gamma 1 [Source:HGNC Symbol;Acc:HGNC:2454]",{"v":2.722213,"d":"2.72"},{"v":1.588755,"d":"1.59"},{"v":1.71342529213126,"d":"1.71"},{"v":0.776883289597729,"d":"0.78"},{"v":0.382614007237806,"d":"0.38"},{"v":0.727196579976147,"d":"0.73"},"up","no"]
[10739,0,"chr1","+",151057758,151068497,"ENST00000368921",2,4075,"MSTRG.943","MLLT11","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0005856(cytoskeleton);GO:0045893(positive regulation of transcription, DNA-templated);GO:0005815(microtubule organizing center);GO:0003674(molecular_function);GO:0005622(intracellular);GO:0043065(positive regulation of apoptotic process);GO:0097190(apoptotic signaling pathway);GO:0097191(extrinsic apoptotic signaling pathway);GO:0090200(positive regulation of release of cytochrome c from mitochondria);GO:0097193(intrinsic apoptotic signaling pathway);GO:0051901(positive regulation of mitochondrial depolarization)","NA","NA","NA","MLLT11, transcription factor 7 cofactor [Source:HGNC Symbol;Acc:HGNC:16997]",{"v":0.484257,"d":"0.48"},{"v":0.635729,"d":"0.64"},{"v":0.761734953101086,"d":"0.76"},{"v":-0.392638997909107,"d":"-0.39"},{"v":0.389477913037974,"d":"0.39"},{"v":0.732046822112028,"d":"0.73"},"down","no"]
[97617,0,"chr19","+",14529592,14565977,"ENST00000596073",13,1170,"MSTRG.7906","TECR","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005783(endoplasmic reticulum);GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0016627(oxidoreductase activity, acting on the CH-CH group of donors);GO:0006629(lipid metabolic process);GO:0005789(endoplasmic reticulum membrane);GO:0006631(fatty acid metabolic process);GO:0006633(fatty acid biosynthetic process);GO:0042761(very long-chain fatty acid biosynthetic process);GO:0005515(protein binding);GO:0035338(long-chain fatty-acyl-CoA biosynthetic process);GO:0030176(integral component of endoplasmic reticulum membrane);GO:0030497(fatty acid elongation);GO:0017099(very-long-chain-acyl-CoA dehydrogenase activity)","00062(Fatty acid elongation);01040(Biosynthesis of unsaturated fatty acids)","K10258","EC:1.3.1.93","trans-2,3-enoyl-CoA reductase [Source:HGNC Symbol;Acc:HGNC:4551]",{"v":2.340289,"d":"2.34"},{"v":1.352412,"d":"1.35"},{"v":1.73045565996161,"d":"1.73"},{"v":0.791151975324196,"d":"0.79"},{"v":0.393866419362983,"d":"0.39"},{"v":0.734593383561713,"d":"0.73"},"up","no"]
[4221,0,"chr1","+",35808172,35857890,"ENST00000373210",18,7116,"MSTRG.407","AGO4","GO:0005737(cytoplasm);GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0016020(membrane);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0030529(intracellular ribonucleoprotein complex);GO:0005515(protein binding);GO:0016604(nuclear body);GO:0031047(gene silencing by RNA);GO:0000932(P-body);GO:0006417(regulation of translation);GO:0038111(interleukin-7-mediated signaling pathway);GO:0048015(phosphatidylinositol-mediated signaling);GO:0045652(regulation of megakaryocyte differentiation);GO:0007223(Wnt signaling pathway, calcium modulating pathway);GO:0003725(double-stranded RNA binding);GO:0031054(pre-miRNA processing);GO:0035196(production of miRNAs involved in gene silencing by miRNA);GO:0070578(RISC-loading complex);GO:0006402(mRNA catabolic process);GO:0035278(miRNA mediated inhibition of translation);GO:0010501(RNA secondary structure unwinding);GO:0035280(miRNA loading onto RISC involved in gene silencing by miRNA);GO:0035194(posttranscriptional gene silencing by RNA);GO:0003727(single-stranded RNA binding);GO:0035198(miRNA binding);GO:0016442(RISC complex);GO:0007130(synaptonemal complex assembly);GO:0007140(male meiotic nuclear division);GO:0008584(male gonad development);GO:0010586(miRNA metabolic process);GO:0022604(regulation of cell morphogenesis);GO:0043066(negative regulation of apoptotic process);GO:0005634(nucleus);GO:0035068(micro-ribonucleoprotein complex)","NA","NA","NA","argonaute 4, RISC catalytic component [Source:HGNC Symbol;Acc:HGNC:18424]",{"v":11.9654,"d":"11.97"},{"v":7.140443,"d":"7.14"},{"v":1.67572236064345,"d":"1.68"},{"v":0.744783138235851,"d":"0.74"},{"v":0.406794696066613,"d":"0.41"},{"v":0.744373353594057,"d":"0.74"},"up","no"]
[123951,0,"chr20","-",44497431,44522109,"ENST00000342374",10,4445,"MSTRG.9756","SERINC3","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0006665(sphingolipid metabolic process);GO:0006658(phosphatidylserine metabolic process);GO:0005737(cytoplasm);GO:0005794(Golgi apparatus);GO:0005886(plasma membrane);GO:0000139(Golgi membrane);GO:0048471(perinuclear region of cytoplasm);GO:0002376(immune system process);GO:0045087(innate immune response);GO:0051607(defense response to virus);GO:0015194(L-serine transmembrane transporter activity);GO:0015825(L-serine transport);GO:0009597(detection of virus);GO:0006564(L-serine biosynthetic process);GO:0006810(transport);GO:1905361(L-serine transporter activity);GO:1902237(positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)","NA","NA","NA","serine incorporator 3 [Source:HGNC Symbol;Acc:HGNC:11699]",{"v":32.890636,"d":"32.89"},{"v":19.750961,"d":"19.75"},{"v":1.66526762925612,"d":"1.67"},{"v":0.735754054997917,"d":"0.74"},{"v":0.414235061957558,"d":"0.41"},{"v":0.750492895624991,"d":"0.75"},"up","no"]
[120139,0,"chr2","+",231781671,231807724,"ENST00000410024",7,1103,"MSTRG.9496","COPS7B","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005654(nucleoplasm);GO:0005515(protein binding);GO:0008180(COP9 signalosome);GO:0005829(cytosol);GO:0043687(post-translational protein modification);GO:0000338(protein deneddylation);GO:0006283(transcription-coupled nucleotide-excision repair);GO:0000715(nucleotide-excision repair, DNA damage recognition)","NA","NA","NA","COP9 signalosome subunit 7B [Source:HGNC Symbol;Acc:HGNC:16760]",{"v":3.86274,"d":"3.86"},{"v":2.293982,"d":"2.29"},{"v":1.68385802504117,"d":"1.68"},{"v":0.751770502297544,"d":"0.75"},{"v":0.4188639943212,"d":"0.42"},{"v":0.752523853166088,"d":"0.75"},"up","no"]
[25662,0,"chr11","-",3826978,3840983,"ENST00000351018",2,1319,"MSTRG.2130","RHOG","GO:0016020(membrane);GO:0005525(GTP binding);GO:0007264(small GTPase mediated signal transduction);GO:0000166(nucleotide binding);GO:0003924(GTPase activity);GO:0005622(intracellular);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0005925(focal adhesion);GO:0005789(endoplasmic reticulum membrane);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0051056(regulation of small GTPase mediated signal transduction);GO:0090630(activation of GTPase activity);GO:0043312(neutrophil degranulation);GO:0007266(Rho protein signal transduction);GO:0030667(secretory granule membrane);GO:0030168(platelet activation);GO:0060326(cell chemotaxis);GO:0045893(positive regulation of transcription, DNA-templated);GO:0008284(positive regulation of cell proliferation);GO:0090004(positive regulation of establishment of protein localization to plasma membrane);GO:0016601(Rac protein signal transduction);GO:0030036(actin cytoskeleton organization);GO:1900027(regulation of ruffle assembly)","05132(Salmonella infection);05131(Shigellosis);05100(Bacterial invasion of epithelial cells)","K07863","NA","ras homolog family member G [Source:HGNC Symbol;Acc:HGNC:672]",{"v":122.287933,"d":"122.29"},{"v":74.040466,"d":"74.04"},{"v":1.65163645782564,"d":"1.65"},{"v":0.723896169681306,"d":"0.72"},{"v":0.424666172311014,"d":"0.42"},{"v":0.756586735452831,"d":"0.76"},"up","no"]
[74396,0,"chr16","-",67229389,67247658,"ENST00000258201",22,3990,"MSTRG.6016","FHOD1","GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005829(cytosol);GO:0003779(actin binding);GO:0005856(cytoskeleton);GO:0042995(cell projection);GO:0042802(identical protein binding);GO:0005515(protein binding);GO:0019904(protein domain specific binding);GO:0051496(positive regulation of stress fiber assembly);GO:0032059(bleb);GO:0001725(stress fiber);GO:0043621(protein self-association);GO:0051492(regulation of stress fiber assembly);GO:0007097(nuclear migration);GO:0051660(establishment of centrosome localization);GO:0014704(intercalated disc)","NA","NA","NA","formin homology 2 domain containing 1 [Source:HGNC Symbol;Acc:HGNC:17905]",{"v":5.873215,"d":"5.87"},{"v":3.571832,"d":"3.57"},{"v":1.6443144582388,"d":"1.64"},{"v":0.717486226002142,"d":"0.72"},{"v":0.43236865178272,"d":"0.43"},{"v":0.762949070936014,"d":"0.76"},"up","no"]
[97126,0,"chr19","-",12730640,12734657,"ENST00000591254",3,988,"MSTRG.7842","TRIR","GO:0005515(protein binding)","NA","NA","NA","telomerase RNA component interacting RNase [Source:HGNC Symbol;Acc:HGNC:28424]",{"v":2.103322,"d":"2.10"},{"v":2.650789,"d":"2.65"},{"v":0.793470170579401,"d":"0.79"},{"v":-0.333752106944834,"d":"-0.33"},{"v":0.438137800977793,"d":"0.44"},{"v":0.766748178915236,"d":"0.77"},"down","no"]
[100230,0,"chr19","-",35738801,35742450,"ENST00000246532",5,1645,"MSTRG.8079","IGFLR1","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005886(plasma membrane);GO:0005515(protein binding)","NA","NA","NA","IGF like family receptor 1 [Source:HGNC Symbol;Acc:HGNC:23620]",{"v":4.707673,"d":"4.71"},{"v":5.823292,"d":"5.82"},{"v":0.808421250385521,"d":"0.81"},{"v":-0.306820849588734,"d":"-0.31"},{"v":0.445564855965768,"d":"0.45"},{"v":0.772378249881795,"d":"0.77"},"down","no"]
[104425,0,"chr19","+",50723329,50725717,"ENST00000250340",4,1419,"ENSG00000105472","CLEC11A","GO:0005737(cytoplasm);GO:0030246(carbohydrate binding);GO:0008083(growth factor activity);GO:0005576(extracellular region);GO:0005615(extracellular space);GO:0008284(positive regulation of cell proliferation);GO:0001503(ossification)","NA","NA","NA","C-type lectin domain containing 11A [Source:HGNC Symbol;Acc:HGNC:10576]",{"v":0.710763,"d":"0.71"},{"v":0.895783,"d":"0.90"},{"v":0.793454441533273,"d":"0.79"},{"v":-0.33378070593016,"d":"-0.33"},{"v":0.450667598875033,"d":"0.45"},{"v":0.774750244444341,"d":"0.77"},"down","no"]
[19208,0,"chr10","+",26697659,26746798,"ENST00000376215",12,1626,"MSTRG.1619","PDSS1","GO:0046872(metal ion binding);GO:0016740(transferase activity);GO:0005739(mitochondrion);GO:0008299(isoprenoid biosynthetic process);GO:0005759(mitochondrial matrix);GO:0006744(ubiquinone biosynthetic process);GO:1990234(transferase complex);GO:0046982(protein heterodimerization activity);GO:0000010(trans-hexaprenyltranstransferase activity);GO:0050347(trans-octaprenyltranstransferase activity);GO:0051290(protein heterotetramerization)","00900(Terpenoid backbone biosynthesis)","K12504","EC:2.5.1.91","decaprenyl diphosphate synthase subunit 1 [Source:HGNC Symbol;Acc:HGNC:17759]",{"v":1.398887,"d":"1.40"},{"v":1.732879,"d":"1.73"},{"v":0.80726178804175,"d":"0.81"},{"v":-0.308891491937292,"d":"-0.31"},{"v":0.459485360166598,"d":"0.46"},{"v":0.780387632561723,"d":"0.78"},"down","no"]
[97423,0,"chr19","+",13805061,13831274,"ENST00000590508",12,2921,"ENSG00000132003","ZSWIM4","GO:0008270(zinc ion binding);GO:0046872(metal ion binding)","NA","NA","NA","zinc finger SWIM-type containing 4 [Source:HGNC Symbol;Acc:HGNC:25704]",{"v":0.726789,"d":"0.73"},{"v":0.443017,"d":"0.44"},{"v":1.64054426805292,"d":"1.64"},{"v":0.714174523718415,"d":"0.71"},{"v":0.470054794274579,"d":"0.47"},{"v":0.78705739288419,"d":"0.79"},"up","no"]
[71967,0,"chr16","-",30580656,30585771,"ENST00000395216",3,3282,"MSTRG.5848","ZNF785","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0005622(intracellular);GO:0005515(protein binding)","NA","NA","NA","zinc finger protein 785 [Source:HGNC Symbol;Acc:HGNC:26496]",{"v":0.952783,"d":"0.95"},{"v":0.590816,"d":"0.59"},{"v":1.61265605535395,"d":"1.61"},{"v":0.689438775662454,"d":"0.69"},{"v":0.47566575158306,"d":"0.48"},{"v":0.790300074922383,"d":"0.79"},"up","no"]
[29617,0,"chr11","-",59806135,59810872,"ENST00000300151",4,1182,"MSTRG.2425","MRPL16","GO:0030529(intracellular ribonucleoprotein complex);GO:0003735(structural constituent of ribosome);GO:0006412(translation);GO:0005840(ribosome);GO:0005739(mitochondrion);GO:0019843(rRNA binding);GO:0032543(mitochondrial translation);GO:0005743(mitochondrial inner membrane);GO:0070125(mitochondrial translational elongation);GO:0070126(mitochondrial translational termination);GO:0005762(mitochondrial large ribosomal subunit)","03010(Ribosome)","K02878","NA","mitochondrial ribosomal protein L16 [Source:HGNC Symbol;Acc:HGNC:14476]",{"v":8.942645,"d":"8.94"},{"v":10.729506,"d":"10.73"},{"v":0.833462882634112,"d":"0.83"},{"v":-0.262810143104649,"d":"-0.26"},{"v":0.483535791343282,"d":"0.48"},{"v":0.796156285496827,"d":"0.80"},"down","no"]
[3246,0,"chr1","+",27342041,27353893,"ENST00000616558",15,1878,"MSTRG.295","SYTL1","GO:0005622(intracellular);GO:0006886(intracellular protein transport);GO:0006887(exocytosis);GO:0017137(Rab GTPase binding);GO:0016020(membrane);GO:0005886(plasma membrane);GO:0042470(melanosome);GO:0098793(presynapse);GO:0005509(calcium ion binding);GO:0005544(calcium-dependent phospholipid binding);GO:0019905(syntaxin binding);GO:0030276(clathrin binding);GO:0006906(vesicle fusion);GO:0017158(regulation of calcium ion-dependent exocytosis);GO:0048791(calcium ion-regulated exocytosis of neurotransmitter);GO:0070382(exocytic vesicle);GO:0005515(protein binding);GO:0070062(extracellular exosome);GO:0061024(membrane organization);GO:0019897(extrinsic component of plasma membrane);GO:0042043(neurexin family protein binding);GO:0031528(microvillus membrane)","NA","NA","NA","synaptotagmin like 1 [Source:HGNC Symbol;Acc:HGNC:15584]",{"v":15.403082,"d":"15.40"},{"v":18.356339,"d":"18.36"},{"v":0.839115141641261,"d":"0.84"},{"v":-0.253059307014401,"d":"-0.25"},{"v":0.48997217763156,"d":"0.49"},{"v":0.800504503678238,"d":"0.80"},"down","no"]
[1125,0,"chr1","+",6585302,6589280,"ENST00000482360",7,2484,"ENSG00000204859","ZBTB48","GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0005694(chromosome);GO:0005515(protein binding);GO:0045893(positive regulation of transcription, DNA-templated);GO:0042802(identical protein binding);GO:0000781(chromosome, telomeric region);GO:0044212(transcription regulatory region DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0003691(double-stranded telomeric DNA binding);GO:0010833(telomere maintenance via telomere lengthening)","NA","NA","NA","zinc finger and BTB domain containing 48 [Source:HGNC Symbol;Acc:HGNC:4930]",{"v":1.248101,"d":"1.25"},{"v":0.78626,"d":"0.79"},{"v":1.58738966754,"d":"1.59"},{"v":0.666656319995306,"d":"0.67"},{"v":0.495761902684475,"d":"0.50"},{"v":0.803977752034125,"d":"0.80"},"up","no"]
[124912,0,"chr20","-",57648392,57709902,"ENST00000341744",4,4845,"ENSG00000124225","PMEPA1","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0043231(intracellular membrane-bounded organelle);GO:0005794(Golgi apparatus);GO:0000139(Golgi membrane);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0005768(endosome);GO:0010008(endosome membrane);GO:0031901(early endosome membrane);GO:0030521(androgen receptor signaling pathway);GO:0009968(negative regulation of signal transduction);GO:0030512(negative regulation of transforming growth factor beta receptor signaling pathway);GO:0070412(R-SMAD binding);GO:0010991(negative regulation of SMAD protein complex assembly);GO:0060394(negative regulation of pathway-restricted SMAD protein phosphorylation);GO:0050699(WW domain binding)","NA","NA","NA","prostate transmembrane protein, androgen induced 1 [Source:HGNC Symbol;Acc:HGNC:14107]",{"v":0.596225,"d":"0.60"},{"v":0.376963,"d":"0.38"},{"v":1.58165390237238,"d":"1.58"},{"v":0.661433943706447,"d":"0.66"},{"v":0.50237394124234,"d":"0.50"},{"v":0.807552847222048,"d":"0.81"},"up","no"]
[158543,"j","chr5","-",135334033,135399256,"MSTRG.12342.2",9,2287,"MSTRG.12342","H2AFY","NA","NA","NA","NA","NA",{"v":18.298954,"d":"18.30"},{"v":21.517336,"d":"21.52"},{"v":0.850428417346831,"d":"0.85"},{"v":-0.233738289080942,"d":"-0.23"},{"v":0.508372139988017,"d":"0.51"},{"v":0.811115220908452,"d":"0.81"},"down","no"]
[121460,0,"chr20","-",1442162,1467692,"ENST00000216879",9,3568,"MSTRG.9549","NSFL1C","GO:0005634(nucleus);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0005794(Golgi apparatus);GO:0005886(plasma membrane);GO:0005694(chromosome);GO:0045111(intermediate filament cytoskeleton);GO:0050790(regulation of catalytic activity);GO:0005515(protein binding);GO:0008289(lipid binding);GO:0043161(proteasome-mediated ubiquitin-dependent protein catabolic process);GO:0000045(autophagosome assembly);GO:0007030(Golgi organization);GO:0043130(ubiquitin binding);GO:0005795(Golgi stack);GO:0061025(membrane fusion);GO:1990730(VCP-NSFL1C complex);GO:0019888(protein phosphatase regulator activity);GO:0031468(nuclear envelope reassembly);GO:0005543(phospholipid binding);GO:0051117(ATPase binding)","04141(Protein processing in endoplasmic reticulum)","K14012","NA","NSFL1 cofactor [Source:HGNC Symbol;Acc:HGNC:15912]",{"v":10.861538,"d":"10.86"},{"v":12.655333,"d":"12.66"},{"v":0.858257779546378,"d":"0.86"},{"v":-0.220517065557015,"d":"-0.22"},{"v":0.521313885549622,"d":"0.52"},{"v":0.818256458099145,"d":"0.82"},"down","no"]
[152568,0,"chr4","+",183659267,183713592,"ENST00000334690",30,4552,"MSTRG.11930","TRAPPC11","GO:0006810(transport);GO:0005794(Golgi apparatus);GO:0043547(positive regulation of GTPase activity);GO:0016192(vesicle-mediated transport);GO:0005515(protein binding);GO:0005829(cytosol);GO:0061635(regulation of protein complex stability);GO:0017112(Rab guanyl-nucleotide exchange factor activity);GO:0061024(membrane organization);GO:0006888(ER to Golgi vesicle-mediated transport);GO:0051259(protein oligomerization);GO:0007030(Golgi organization);GO:0030008(TRAPP complex)","NA","NA","NA","trafficking protein particle complex 11 [Source:HGNC Symbol;Acc:HGNC:25751]",{"v":6.608305,"d":"6.61"},{"v":4.31058,"d":"4.31"},{"v":1.53304311716753,"d":"1.53"},{"v":0.616398273675749,"d":"0.62"},{"v":0.526778868861922,"d":"0.53"},{"v":0.820847959032442,"d":"0.82"},"up","no"]
[137241,0,"chr3","+",53161199,53192554,"ENST00000330452",19,2680,"MSTRG.10988","PRKCD","GO:0050728(negative regulation of inflammatory response);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0005829(cytosol);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0035556(intracellular signal transduction);GO:0018108(peptidyl-tyrosine phosphorylation);GO:0005783(endoplasmic reticulum);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0007049(cell cycle);GO:0004715(non-membrane spanning protein tyrosine kinase activity);GO:0006915(apoptotic process);GO:0004697(protein kinase C activity);GO:0043560(insulin receptor substrate binding);GO:0016064(immunoglobulin mediated immune response);GO:0030837(negative regulation of actin filament polymerization);GO:0032613(interleukin-10 production);GO:0032615(interleukin-12 production);GO:0042100(B cell proliferation);GO:0042742(defense response to bacterium);GO:0046627(negative regulation of insulin receptor signaling pathway);GO:0050732(negative regulation of peptidyl-tyrosine phosphorylation);GO:0051490(negative regulation of filopodium assembly);GO:0090331(negative regulation of platelet aggregation);GO:2001235(positive regulation of apoptotic signaling pathway);GO:0005911(cell-cell junction);GO:0016363(nuclear matrix);GO:0048471(perinuclear region of cytoplasm);GO:0038096(Fc-gamma receptor signaling pathway involved in phagocytosis);GO:0005576(extracellular region);GO:0005654(nucleoplasm);GO:0070062(extracellular exosome);GO:0019901(protein kinase binding);GO:0050821(protein stabilization);GO:0002223(stimulatory C-type lectin receptor signaling pathway);GO:0043488(regulation of mRNA stability);GO:0042307(positive regulation of protein import into nucleus);GO:0043312(neutrophil degranulation);GO:0007165(signal transduction);GO:0019899(enzyme binding);GO:0030168(platelet activation);GO:0097194(execution phase of apoptosis);GO:0034351(negative regulation of glial cell apoptotic process);GO:0035578(azurophil granule lumen);GO:0060326(cell chemotaxis);GO:0060333(interferon-gamma-mediated signaling pathway);GO:0032091(negative regulation of protein binding);GO:0018107(peptidyl-threonine phosphorylation);GO:0008047(enzyme activator activity);GO:0019900(kinase binding);GO:0016572(histone phosphorylation);GO:0032930(positive regulation of superoxide anion generation);GO:0070301(cellular response to hydrogen peroxide);GO:0010469(regulation of receptor activity);GO:2001022(positive regulation of response to DNA damage stimulus);GO:0090398(cellular senescence);GO:0018105(peptidyl-serine phosphorylation);GO:0035307(positive regulation of protein dephosphorylation);GO:0043407(negative regulation of MAP kinase activity);GO:0023021(termination of signal transduction);GO:0042119(neutrophil activation);GO:0032079(positive regulation of endodeoxyribonuclease activity);GO:0007202(activation of phospholipase C activity);GO:0004699(calcium-independent protein kinase C activity);GO:0008631(intrinsic apoptotic signaling pathway in response to oxidative stress);GO:0032147(activation of protein kinase activity);GO:0032956(regulation of actin cytoskeleton organization);GO:0071447(cellular response to hydroperoxide);GO:1900163(positive regulation of phospholipid scramblase activity);GO:1904385(cellular response to angiotensin);GO:2000304(positive regulation of ceramide biosynthetic process);GO:2000753(positive regulation of glucosylceramide catabolic process);GO:2000755(positive regulation of sphingomyelin catabolic process)","04140(Autophagy - animal);04621(NOD-like receptor signaling pathway);04666(Fc gamma R-mediated phagocytosis);04062(Chemokine signaling pathway);04912(GnRH signaling pathway);04915(Estrogen signaling pathway);04270(Vascular smooth muscle contraction);04722(Neurotrophin signaling pathway);04750(Inflammatory mediator regulation of TRP channels);04930(Type II diabetes mellitus);04931(Insulin resistance);04933(AGE-RAGE signaling pathway in diabetic complications)","K06068","EC:2.7.11.13","protein kinase C delta [Source:HGNC Symbol;Acc:HGNC:9399]",{"v":36.185421,"d":"36.19"},{"v":23.727699,"d":"23.73"},{"v":1.52502865954259,"d":"1.53"},{"v":0.608836355194508,"d":"0.61"},{"v":0.533046146332559,"d":"0.53"},{"v":0.823669931565569,"d":"0.82"},"up","no"]
[108955,0,"chr2","-",38744918,38751352,"ENST00000443213",7,1903,"MSTRG.8650","SRSF7","GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0006397(mRNA processing);GO:0006810(transport);GO:0008380(RNA splicing);GO:0051028(mRNA transport);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0005654(nucleoplasm);GO:0005515(protein binding);GO:0070062(extracellular exosome);GO:0006369(termination of RNA polymerase II transcription);GO:0006405(RNA export from nucleus);GO:0031124(mRNA 3'-end processing);GO:0019904(protein domain specific binding);GO:0048025(negative regulation of mRNA splicing, via spliceosome);GO:0000398(mRNA splicing, via spliceosome);GO:0006406(mRNA export from nucleus);GO:1990830(cellular response to leukemia inhibitory factor)","03040(Spliceosome);05168(Herpes simplex infection)","K12896","NA","serine and arginine rich splicing factor 7 [Source:HGNC Symbol;Acc:HGNC:10789]",{"v":8.818804,"d":"8.82"},{"v":10.153982,"d":"10.15"},{"v":0.868506956187238,"d":"0.87"},{"v":-0.203390690837542,"d":"-0.20"},{"v":0.540618985255014,"d":"0.54"},{"v":0.828342677769149,"d":"0.83"},"down","no"]
[92620,0,"chr18","+",54357917,54382035,"ENST00000620105",9,5693,"ENSG00000166845","C18orf54","GO:0005515(protein binding);GO:0005576(extracellular region);GO:0008285(negative regulation of cell proliferation)","NA","NA","NA","chromosome 18 open reading frame 54 [Source:HGNC Symbol;Acc:HGNC:13796]",{"v":0.362884,"d":"0.36"},{"v":0.236065,"d":"0.24"},{"v":1.53722068074471,"d":"1.54"},{"v":0.620324290703529,"d":"0.62"},{"v":0.545837983525447,"d":"0.55"},{"v":0.830405900567238,"d":"0.83"},"up","no"]
[96133,0,"chr19","-",9433774,9435578,"ENST00000588013",5,617,"MSTRG.7778","ZNF266","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0005622(intracellular);GO:0005515(protein binding)","NA","NA","NA","zinc finger protein 266 [Source:HGNC Symbol;Acc:HGNC:13059]",{"v":2.477051,"d":"2.48"},{"v":2.878708,"d":"2.88"},{"v":0.860473170602923,"d":"0.86"},{"v":-0.216797884889797,"d":"-0.22"},{"v":0.552407336029975,"d":"0.55"},{"v":0.834539389819692,"d":"0.83"},"down","no"]
[4764,0,"chr1","+",40691709,40771603,"ENST00000447388",10,1950,"MSTRG.466","NFYC","GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0006355(regulation of transcription, DNA-templated);GO:0006366(transcription from RNA polymerase II promoter);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0046982(protein heterodimerization activity);GO:0005515(protein binding);GO:0016602(CCAAT-binding factor complex);GO:0003713(transcription coactivator activity);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0090575(RNA polymerase II transcription factor complex);GO:0045540(regulation of cholesterol biosynthetic process);GO:0006457(protein folding);GO:0044212(transcription regulatory region DNA binding);GO:0000980(RNA polymerase II distal enhancer sequence-specific DNA binding);GO:0032993(protein-DNA complex);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:0001077(transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0008134(transcription factor binding);GO:0045893(positive regulation of transcription, DNA-templated);GO:0045944(positive regulation of transcription from RNA polymerase II promoter)","04612(Antigen processing and presentation);05152(Tuberculosis)","K08066","NA","nuclear transcription factor Y subunit gamma [Source:HGNC Symbol;Acc:HGNC:7806]",{"v":14.983745,"d":"14.98"},{"v":9.987924,"d":"9.99"},{"v":1.50018612476427,"d":"1.50"},{"v":0.585141503798679,"d":"0.59"},{"v":0.559152453681992,"d":"0.56"},{"v":0.837790061801186,"d":"0.84"},"up","no"]
[164414,0,"chr6","-",31532413,31542001,"ENST00000481456",5,5158,"MSTRG.12858","DDX39B","GO:0003676(nucleic acid binding);GO:0016607(nuclear speck);GO:0005524(ATP binding);GO:0003723(RNA binding);GO:0006397(mRNA processing);GO:0006810(transport);GO:0008380(RNA splicing);GO:0051028(mRNA transport);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0000166(nucleotide binding);GO:0016787(hydrolase activity);GO:0004386(helicase activity);GO:0005515(protein binding);GO:0005681(spliceosomal complex);GO:0006406(mRNA export from nucleus);GO:0042802(identical protein binding);GO:0005730(nucleolus);GO:0005654(nucleoplasm);GO:0016887(ATPase activity);GO:0000398(mRNA splicing, via spliceosome);GO:0006369(termination of RNA polymerase II transcription);GO:0006405(RNA export from nucleus);GO:0031124(mRNA 3'-end processing);GO:0032786(positive regulation of DNA-templated transcription, elongation);GO:0004004(ATP-dependent RNA helicase activity);GO:0000346(transcription export complex);GO:0008186(RNA-dependent ATPase activity);GO:0046784(viral mRNA export from host cell nucleus);GO:2000002(negative regulation of DNA damage checkpoint);GO:0005687(U4 snRNP);GO:0005688(U6 snRNP);GO:0017070(U6 snRNA binding);GO:0030621(U4 snRNA binding);GO:0043008(ATP-dependent protein binding);GO:0000245(spliceosomal complex assembly);GO:0010501(RNA secondary structure unwinding);GO:0032403(protein complex binding);GO:0001889(liver development);GO:0045727(positive regulation of translation);GO:0061051(positive regulation of cell growth involved in cardiac muscle cell development);GO:1904707(positive regulation of vascular smooth muscle cell proliferation);GO:2000573(positive regulation of DNA biosynthetic process);GO:0016363(nuclear matrix);GO:0043234(protein complex)","03040(Spliceosome);03013(RNA transport);03015(mRNA surveillance pathway);05164(Influenza A)","NA","NA","DExD-box helicase 39B [Source:HGNC Symbol;Acc:HGNC:13917]",{"v":2.918304,"d":"2.92"},{"v":1.964805,"d":"1.96"},{"v":1.48528937986212,"d":"1.49"},{"v":0.570744039591537,"d":"0.57"},{"v":0.572320963885626,"d":"0.57"},{"v":0.844401992861212,"d":"0.84"},"up","no"]
[56625,0,"chr14","+",73591706,73596496,"ENST00000326303",3,2362,"ENSG00000177465","ACOT4","GO:0016787(hydrolase activity);GO:0016790(thiolester hydrolase activity);GO:0005777(peroxisome);GO:0006637(acyl-CoA metabolic process);GO:0052689(carboxylic ester hydrolase activity);GO:0005102(receptor binding);GO:0047617(acyl-CoA hydrolase activity);GO:0005782(peroxisomal matrix);GO:0016290(palmitoyl-CoA hydrolase activity);GO:0102991(myristoyl-CoA hydrolase activity);GO:0043649(dicarboxylic acid catabolic process);GO:0000038(very long-chain fatty acid metabolic process);GO:0001676(long-chain fatty acid metabolic process);GO:0004778(succinyl-CoA hydrolase activity);GO:0006104(succinyl-CoA metabolic process);GO:0032788(saturated monocarboxylic acid metabolic process);GO:0032789(unsaturated monocarboxylic acid metabolic process);GO:0043648(dicarboxylic acid metabolic process);GO:0046459(short-chain fatty acid metabolic process)","00062(Fatty acid elongation);01040(Biosynthesis of unsaturated fatty acids)","K01068","EC:3.1.2.2","acyl-CoA thioesterase 4 [Source:HGNC Symbol;Acc:HGNC:19748]",{"v":0.51651,"d":"0.52"},{"v":0.595906,"d":"0.60"},{"v":0.866764221202673,"d":"0.87"},{"v":-0.206288492631151,"d":"-0.21"},{"v":0.57900281128826,"d":"0.58"},{"v":0.847424302540804,"d":"0.85"},"down","no"]
[170490,0,"chr6","-",158109515,158168270,"ENST00000367104",17,3948,"ENSG00000122335","SERAC1","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0006629(lipid metabolic process);GO:0005783(endoplasmic reticulum);GO:0005739(mitochondrion);GO:0008654(phospholipid biosynthetic process);GO:0030198(extracellular matrix organization);GO:0005578(proteinaceous extracellular matrix)","NA","NA","NA","serine active site containing 1 [Source:HGNC Symbol;Acc:HGNC:21061]",{"v":0.889398,"d":"0.89"},{"v":0.601588,"d":"0.60"},{"v":1.47841712268197,"d":"1.48"},{"v":0.564053370920525,"d":"0.56"},{"v":0.584288744588618,"d":"0.58"},{"v":0.84941516274492,"d":"0.85"},"up","no"]
[108522,0,"chr2","+",31234337,31269447,"ENST00000322054",6,4636,"ENSG00000013016","EHD3","GO:0006810(transport);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0015031(protein transport);GO:0005829(cytosol);GO:0005525(GTP binding);GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0005509(calcium ion binding);GO:0005886(plasma membrane);GO:0042995(cell projection);GO:0005515(protein binding);GO:0005925(focal adhesion);GO:0005768(endosome);GO:0060271(cilium assembly);GO:0005929(cilium);GO:0030030(cell projection organization);GO:0010008(endosome membrane);GO:0055038(recycling endosome membrane);GO:0060170(ciliary membrane);GO:0005634(nucleus);GO:0007596(blood coagulation);GO:0051260(protein homooligomerization);GO:0090160(Golgi to lysosome transport);GO:0003676(nucleic acid binding);GO:0032456(endocytic recycling);GO:0020018(ciliary pocket membrane);GO:0034498(early endosome to Golgi transport);GO:1903358(regulation of Golgi organization);GO:0001881(receptor recycling);GO:0055117(regulation of cardiac muscle contraction);GO:0072661(protein targeting to plasma membrane);GO:0086036(regulation of cardiac muscle cell membrane potential);GO:1901387(positive regulation of voltage-gated calcium channel activity);GO:1903779(regulation of cardiac conduction);GO:0030139(endocytic vesicle);GO:0043209(myelin sheath);GO:0048471(perinuclear region of cytoplasm)","04144(Endocytosis)","K12476","NA","EH domain containing 3 [Source:HGNC Symbol;Acc:HGNC:3244]",{"v":4.515672,"d":"4.52"},{"v":3.074598,"d":"3.07"},{"v":1.46870322559242,"d":"1.47"},{"v":0.554542906295239,"d":"0.55"},{"v":0.590912805047885,"d":"0.59"},{"v":0.853315521147745,"d":"0.85"},"up","no"]
[170339,0,"chr6","-",154154609,154356766,"ENST00000265198",12,6689,"ENSG00000074706","IPCEF1","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005886(plasma membrane);GO:0098869(cellular oxidant detoxification);GO:0004601(peroxidase activity);GO:0005344(oxygen transporter activity);GO:0015671(oxygen transport);GO:0006979(response to oxidative stress);GO:0019904(protein domain specific binding);GO:0005829(cytosol)","NA","NA","NA","interaction protein for cytohesin exchange factors 1 [Source:HGNC Symbol;Acc:HGNC:21204]",{"v":0.304396,"d":"0.30"},{"v":0.341877,"d":"0.34"},{"v":0.890367003337458,"d":"0.89"},{"v":-0.167527966946371,"d":"-0.17"},{"v":0.601402365963846,"d":"0.60"},{"v":0.859431647121584,"d":"0.86"},"down","no"]
[165068,0,"chr6","-",32841021,32844651,"ENST00000484003",5,1153,"MSTRG.12918","PSMB8","GO:0004298(threonine-type endopeptidase activity);GO:0051603(proteolysis involved in cellular protein catabolic process);GO:0005839(proteasome core complex);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016787(hydrolase activity);GO:0005515(protein binding);GO:0008233(peptidase activity);GO:0006508(proteolysis);GO:0000502(proteasome complex);GO:0030154(cell differentiation);GO:0002376(immune system process);GO:0004175(endopeptidase activity);GO:0038095(Fc-epsilon receptor signaling pathway);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0045444(fat cell differentiation);GO:0000165(MAPK cascade);GO:0000209(protein polyubiquitination);GO:0002223(stimulatory C-type lectin receptor signaling pathway);GO:0002479(antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent);GO:0006521(regulation of cellular amino acid metabolic process);GO:0010972(negative regulation of G2/M transition of mitotic cell cycle);GO:0016579(protein deubiquitination);GO:0031145(anaphase-promoting complex-dependent catabolic process);GO:0031146(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process);GO:0033209(tumor necrosis factor-mediated signaling pathway);GO:0038061(NIK/NF-kappaB signaling);GO:0043161(proteasome-mediated ubiquitin-dependent protein catabolic process);GO:0043488(regulation of mRNA stability);GO:0043687(post-translational protein modification);GO:0050852(T cell receptor signaling pathway);GO:0051437(positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition);GO:0055085(transmembrane transport);GO:0060071(Wnt signaling pathway, planar cell polarity pathway);GO:0061418(regulation of transcription from RNA polymerase II promoter in response to hypoxia);GO:0090090(negative regulation of canonical Wnt signaling pathway);GO:0090263(positive regulation of canonical Wnt signaling pathway);GO:1902036(regulation of hematopoietic stem cell differentiation);GO:0019774(proteasome core complex, beta-subunit complex);GO:0016032(viral process);GO:0052548(regulation of endopeptidase activity);GO:0051436(negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle);GO:0060337(type I interferon signaling pathway);GO:0019882(antigen processing and presentation);GO:1990111(spermatoproteasome complex)","03050(Proteasome)","NA","NA","proteasome subunit beta 8 [Source:HGNC Symbol;Acc:HGNC:9545]",{"v":7.237221,"d":"7.24"},{"v":7.973099,"d":"7.97"},{"v":0.907704896176506,"d":"0.91"},{"v":-0.13970475554532,"d":"-0.14"},{"v":0.606586957262196,"d":"0.61"},{"v":0.863411214954995,"d":"0.86"},"down","no"]
[37288,0,"chr12","-",912155,933076,"ENST00000228345",11,2826,"MSTRG.3009","RAD52","GO:0005634(nucleus);GO:0003677(DNA binding);GO:0006281(DNA repair);GO:0005515(protein binding);GO:0006310(DNA recombination);GO:0006974(cellular response to DNA damage stimulus);GO:0000724(double-strand break repair via homologous recombination);GO:0042802(identical protein binding);GO:0005654(nucleoplasm);GO:0043234(protein complex);GO:0000730(DNA recombinase assembly);GO:0045002(double-strand break repair via single-strand annealing);GO:0051260(protein homooligomerization);GO:0006302(double-strand break repair);GO:0032993(protein-DNA complex);GO:0034599(cellular response to oxidative stress);GO:0003697(single-stranded DNA binding);GO:0010792(DNA double-strand break processing involved in repair via single-strand annealing);GO:2000819(regulation of nucleotide-excision repair)","03440(Homologous recombination)","K10873","NA","RAD52 homolog, DNA repair protein [Source:HGNC Symbol;Acc:HGNC:9824]",{"v":0.388823,"d":"0.39"},{"v":0.436981,"d":"0.44"},{"v":0.889793835429916,"d":"0.89"},{"v":-0.168456991457387,"d":"-0.17"},{"v":0.613022554428781,"d":"0.61"},{"v":0.866773155200908,"d":"0.87"},"down","no"]
[33041,0,"chr11","+",74171099,74254703,"ENST00000328257",14,2677,"ENSG00000214517","PPME1","GO:0016787(hydrolase activity);GO:0050790(regulation of catalytic activity);GO:0043086(negative regulation of catalytic activity);GO:0052689(carboxylic ester hydrolase activity);GO:0051723(protein methylesterase activity);GO:0006482(protein demethylation);GO:0005654(nucleoplasm);GO:0045296(cadherin binding);GO:0000086(G2/M transition of mitotic cell cycle);GO:0004864(protein phosphatase inhibitor activity);GO:0019888(protein phosphatase regulator activity);GO:0051721(protein phosphatase 2A binding);GO:0019903(protein phosphatase binding);GO:0051722(protein C-terminal methylesterase activity);GO:0019901(protein kinase binding)","NA","NA","NA","protein phosphatase methylesterase 1 [Source:HGNC Symbol;Acc:HGNC:30178]",{"v":3.118427,"d":"3.12"},{"v":2.156175,"d":"2.16"},{"v":1.44627731979083,"d":"1.45"},{"v":0.532344211712706,"d":"0.53"},{"v":0.620916728399491,"d":"0.62"},{"v":0.871193479122733,"d":"0.87"},"up","no"]
[186096,0,"chr8","-",100920587,100951594,"ENST00000395953",6,994,"MSTRG.14503","YWHAZ","GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0004497(monooxygenase activity);GO:0055114(oxidation-reduction process);GO:0019904(protein domain specific binding);GO:0005515(protein binding);GO:0042470(melanosome);GO:0005615(extracellular space);GO:0005925(focal adhesion);GO:0042802(identical protein binding);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0045296(cadherin binding);GO:0070062(extracellular exosome);GO:0019901(protein kinase binding);GO:0061024(membrane organization);GO:0072562(blood microparticle);GO:0043488(regulation of mRNA stability);GO:0006605(protein targeting);GO:0010941(regulation of cell death);GO:0005739(mitochondrion);GO:0007165(signal transduction);GO:0008134(transcription factor binding);GO:0030168(platelet activation);GO:0043066(negative regulation of apoptotic process);GO:0031982(vesicle);GO:0051683(establishment of Golgi localization);GO:0090168(Golgi reassembly);GO:1900740(positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway);GO:0031625(ubiquitin protein ligase binding);GO:0030659(cytoplasmic vesicle membrane);GO:0044325(ion channel binding);GO:0016301(kinase activity);GO:0016310(phosphorylation)","04390(Hippo signaling pathway);04151(PI3K-Akt signaling pathway);04110(Cell cycle);04114(Oocyte meiosis);05203(Viral carcinogenesis);05130(Pathogenic Escherichia coli infection);05161(Hepatitis B);05169(Epstein-Barr virus infection)","K16197","NA","tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta [Source:HGNC Symbol;Acc:HGNC:12855]",{"v":12.358729,"d":"12.36"},{"v":13.37243,"d":"13.37"},{"v":0.924194705076041,"d":"0.92"},{"v":-0.113731270890836,"d":"-0.11"},{"v":0.634289125544671,"d":"0.63"},{"v":0.876992149679142,"d":"0.88"},"down","no"]
[146162,0,"chr4","+",15711806,15738308,"ENST00000514445",7,1002,"MSTRG.11546","BST1","GO:0016020(membrane);GO:0016740(transferase activity);GO:0016787(hydrolase activity);GO:0005886(plasma membrane);GO:0031225(anchored component of membrane);GO:0005576(extracellular region);GO:0070062(extracellular exosome);GO:0003953(NAD+ nucleosidase activity);GO:0006501(C-terminal protein lipidation);GO:0043312(neutrophil degranulation);GO:0035579(specific granule membrane);GO:0032956(regulation of actin cytoskeleton organization);GO:0019674(NAD metabolic process);GO:0050848(regulation of calcium-mediated signaling);GO:0008284(positive regulation of cell proliferation);GO:0016849(phosphorus-oxygen lyase activity);GO:0050135(NAD(P)+ nucleosidase activity);GO:0061809(NAD+ nucleotidase, cyclic ADP-ribose generating);GO:0008305(integrin complex);GO:0061811(ADP-ribosyl cyclase activity);GO:0061812(cyclic ADP-ribose hydrolase);GO:0001952(regulation of cell-matrix adhesion);GO:0002691(regulation of cellular extravasation);GO:0006959(humoral immune response);GO:0007165(signal transduction);GO:0030890(positive regulation of B cell proliferation);GO:0050727(regulation of inflammatory response);GO:0050730(regulation of peptidyl-tyrosine phosphorylation);GO:0090022(regulation of neutrophil chemotaxis);GO:0090322(regulation of superoxide metabolic process);GO:2001044(regulation of integrin-mediated signaling pathway);GO:0001931(uropod);GO:0019898(extrinsic component of membrane)","00760(Nicotinate and nicotinamide metabolism);04970(Salivary secretion);04972(Pancreatic secretion)","NA","NA","bone marrow stromal cell antigen 1 [Source:HGNC Symbol;Acc:HGNC:1118]",{"v":1.229541,"d":"1.23"},{"v":0.855152,"d":"0.86"},{"v":1.43780403951578,"d":"1.44"},{"v":0.523867062089112,"d":"0.52"},{"v":0.640511031296981,"d":"0.64"},{"v":0.878965411605822,"d":"0.88"},"up","no"]
[145333,0,"chr4","-",2249464,2255234,"ENST00000513372",3,4228,"MSTRG.11495","MXD4","GO:0005634(nucleus);GO:0046983(protein dimerization activity);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0003714(transcription corepressor activity);GO:0008285(negative regulation of cell proliferation);GO:0000122(negative regulation of transcription from RNA polymerase II promoter)","NA","NA","NA","MAX dimerization protein 4 [Source:HGNC Symbol;Acc:HGNC:13906]",{"v":0.940514,"d":"0.94"},{"v":0.65815,"d":"0.66"},{"v":1.42902681759477,"d":"1.43"},{"v":0.515032990784992,"d":"0.52"},{"v":0.64576530827169,"d":"0.65"},{"v":0.880844000832715,"d":"0.88"},"up","no"]
[155662,0,"chr5","+",71522793,71567820,"ENST00000514903",16,5511,"ENSG00000145734","BDP1","GO:0005634(nucleus);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0001026(TFIIIB-type transcription factor activity);GO:0006359(regulation of transcription from RNA polymerase III promoter);GO:0006383(transcription from RNA polymerase III promoter);GO:0000126(transcription factor TFIIIB complex);GO:0005654(nucleoplasm);GO:0001156(TFIIIC-class transcription factor binding);GO:0070898(RNA polymerase III transcriptional preinitiation complex assembly)","NA","NA","NA","B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB [Source:HGNC Symbol;Acc:HGNC:13652]",{"v":1.212048,"d":"1.21"},{"v":0.856344,"d":"0.86"},{"v":1.41537512962081,"d":"1.42"},{"v":0.501184474200654,"d":"0.50"},{"v":0.652460236860495,"d":"0.65"},{"v":0.884252576412221,"d":"0.88"},"up","no"]
[193299,0,"chr9","-",124857883,124861936,"ENST00000487431",3,785,"MSTRG.14957","RPL35","GO:0005622(intracellular);GO:0003735(structural constituent of ribosome);GO:0006412(translation);GO:0005840(ribosome);GO:0003723(RNA binding);GO:0016020(membrane);GO:0030529(intracellular ribonucleoprotein complex);GO:0005829(cytosol);GO:0006413(translational initiation);GO:0006364(rRNA processing);GO:0005730(nucleolus);GO:0000184(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay);GO:0019083(viral transcription);GO:0006614(SRP-dependent cotranslational protein targeting to membrane);GO:0022625(cytosolic large ribosomal subunit);GO:0003729(mRNA binding);GO:0000463(maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA))","03010(Ribosome)","NA","NA","ribosomal protein L35 [Source:HGNC Symbol;Acc:HGNC:10344]",{"v":2.055829,"d":"2.06"},{"v":1.439781,"d":"1.44"},{"v":1.42787618394742,"d":"1.43"},{"v":0.513870883744061,"d":"0.51"},{"v":0.659067604473885,"d":"0.66"},{"v":0.886763429477748,"d":"0.89"},"up","no"]
[109215,0,"chr2","-",43556093,43596023,"ENST00000404790",17,3043,"ENSG00000115970","THADA","GO:0005515(protein binding);GO:0032471(negative regulation of endoplasmic reticulum calcium ion concentration);GO:0055088(lipid homeostasis);GO:1901895(negative regulation of calcium-transporting ATPase activity);GO:1990845(adaptive thermogenesis);GO:0098554(cytoplasmic side of endoplasmic reticulum membrane);GO:0016020(membrane);GO:0016021(integral component of membrane)","NA","NA","NA","THADA, armadillo repeat containing [Source:HGNC Symbol;Acc:HGNC:19217]",{"v":0.395791,"d":"0.40"},{"v":0.429903,"d":"0.43"},{"v":0.920651867979521,"d":"0.92"},{"v":-0.11927237102108,"d":"-0.12"},{"v":0.668494077574125,"d":"0.67"},{"v":0.890425471663758,"d":"0.89"},"down","no"]
[158501,0,"chr5","+",134873803,134901525,"ENST00000358387",5,3548,"MSTRG.12315","TXNDC15","GO:0005623(cell);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0045454(cell redox homeostasis)","NA","NA","NA","thioredoxin domain containing 15 [Source:HGNC Symbol;Acc:HGNC:20652]",{"v":5.094045,"d":"5.09"},{"v":5.385797,"d":"5.39"},{"v":0.945829373071432,"d":"0.95"},{"v":-0.0803481489824494,"d":"-0.08"},{"v":0.670959651585565,"d":"0.67"},{"v":0.891660723730124,"d":"0.89"},"down","no"]
[53297,0,"chr14","+",23561097,23568073,"ENST00000555968",4,3243,"MSTRG.4278","AL135999.1","NA","NA","NA","NA","NA",{"v":1.172224,"d":"1.17"},{"v":1.236347,"d":"1.24"},{"v":0.948135110935684,"d":"0.95"},{"v":-0.0768354345109567,"d":"-0.08"},{"v":0.678286236005716,"d":"0.68"},{"v":0.894800890585949,"d":"0.89"},"down","no"]
[107451,0,"chr2","+",12716889,12742734,"ENST00000155926",3,4391,"MSTRG.8519","TRIB2","GO:0045599(negative regulation of fat cell differentiation);GO:0005737(cytoplasm);GO:0005856(cytoskeleton);GO:0004860(protein kinase inhibitor activity);GO:0005634(nucleus);GO:0006469(negative regulation of protein kinase activity);GO:0032436(positive regulation of proteasomal ubiquitin-dependent protein catabolic process);GO:0043405(regulation of MAP kinase activity);GO:0031625(ubiquitin protein ligase binding);GO:0008134(transcription factor binding);GO:0031434(mitogen-activated protein kinase kinase binding);GO:0055106(ubiquitin-protein transferase regulator activity);GO:0045081(negative regulation of interleukin-10 biosynthetic process);GO:0004672(protein kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation)","NA","NA","NA","tribbles pseudokinase 2 [Source:HGNC Symbol;Acc:HGNC:30809]",{"v":9.174905,"d":"9.17"},{"v":6.67242,"d":"6.67"},{"v":1.37504908264168,"d":"1.38"},{"v":0.459483116833603,"d":"0.46"},{"v":0.693496372314209,"d":"0.69"},{"v":0.902617253773663,"d":"0.90"},"up","no"]
[31676,0,"chr11","+",66480013,66509657,"ENST00000532677",18,3078,"MSTRG.2592","DPP3","GO:0016607(nuclear speck);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0016787(hydrolase activity);GO:0008270(zinc ion binding);GO:0005515(protein binding);GO:0008233(peptidase activity);GO:0006508(proteolysis);GO:0008237(metallopeptidase activity);GO:0008239(dipeptidyl-peptidase activity);GO:0004177(aminopeptidase activity);GO:0070062(extracellular exosome)","NA","NA","NA","dipeptidyl peptidase 3 [Source:HGNC Symbol;Acc:HGNC:3008]",{"v":1.657672,"d":"1.66"},{"v":1.720566,"d":"1.72"},{"v":0.963445749828835,"d":"0.96"},{"v":-0.0537246620523006,"d":"-0.05"},{"v":0.70159838216078,"d":"0.70"},{"v":0.906748663457483,"d":"0.91"},"down","no"]
[191432,0,"chr9","+",85941146,86022298,"ENST00000361671",23,2649,"ENSG00000135040","NAA35","GO:0005737(cytoplasm);GO:0005515(protein binding);GO:0043066(negative regulation of apoptotic process);GO:0005844(polysome);GO:0048659(smooth muscle cell proliferation);GO:0004596(peptide alpha-N-acetyltransferase activity);GO:0031417(NatC complex);GO:0006474(N-terminal protein amino acid acetylation)","NA","NA","NA","N(alpha)-acetyltransferase 35, NatC auxiliary subunit [Source:HGNC Symbol;Acc:HGNC:24340]",{"v":2.860288,"d":"2.86"},{"v":2.09168,"d":"2.09"},{"v":1.3674596496596,"d":"1.37"},{"v":0.451498263295826,"d":"0.45"},{"v":0.708826615108114,"d":"0.71"},{"v":0.910540940418869,"d":"0.91"},"up","no"]
[7065,0,"chr1","-",68125358,68232553,"ENST00000262348",12,2748,"MSTRG.637","WLS","GO:0090263(positive regulation of canonical Wnt signaling pathway);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005783(endoplasmic reticulum);GO:0005794(Golgi apparatus);GO:0005789(endoplasmic reticulum membrane);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0004871(signal transducer activity);GO:0000139(Golgi membrane);GO:0007275(multicellular organism development);GO:0016055(Wnt signaling pathway);GO:0030659(cytoplasmic vesicle membrane);GO:0031410(cytoplasmic vesicle);GO:0005768(endosome);GO:0017147(Wnt-protein binding);GO:0031901(early endosome membrane);GO:0043123(positive regulation of I-kappaB kinase/NF-kappaB signaling);GO:0030666(endocytic vesicle membrane);GO:0070062(extracellular exosome);GO:0005769(early endosome);GO:0005802(trans-Golgi network);GO:0006886(intracellular protein transport);GO:0009948(anterior/posterior axis specification);GO:0030177(positive regulation of Wnt signaling pathway);GO:0031852(mu-type opioid receptor binding);GO:0001707(mesoderm formation);GO:0030901(midbrain development);GO:0030902(hindbrain development);GO:0031017(exocrine pancreas development);GO:0061355(Wnt protein secretion);GO:0061357(positive regulation of Wnt protein secretion);GO:0032590(dendrite membrane);GO:0032839(dendrite cytoplasm)","NA","NA","NA","wntless Wnt ligand secretion mediator [Source:HGNC Symbol;Acc:HGNC:30238]",{"v":25.907579,"d":"25.91"},{"v":19.108709,"d":"19.11"},{"v":1.35579954668837,"d":"1.36"},{"v":0.439143893536219,"d":"0.44"},{"v":0.715514822962666,"d":"0.72"},{"v":0.913696690686599,"d":"0.91"},"up","no"]
[10643,0,"chr1","-",150796208,150808323,"ENST00000271651",8,1692,"MSTRG.928","CTSK","GO:0005615(extracellular space);GO:0043231(intracellular membrane-bounded organelle);GO:0005654(nucleoplasm);GO:0016787(hydrolase activity);GO:0008233(peptidase activity);GO:0008234(cysteine-type peptidase activity);GO:0006508(proteolysis);GO:0005764(lysosome);GO:0004252(serine-type endopeptidase activity);GO:0005576(extracellular region);GO:0005515(protein binding);GO:0030574(collagen catabolic process);GO:1903146(regulation of mitophagy);GO:0002224(toll-like receptor signaling pathway);GO:0043202(lysosomal lumen);GO:0022617(extracellular matrix disassembly);GO:1903955(positive regulation of protein targeting to mitochondrion);GO:0004197(cysteine-type endopeptidase activity);GO:0045616(regulation of keratinocyte differentiation);GO:0001968(fibronectin binding);GO:0005518(collagen binding);GO:0043394(proteoglycan binding);GO:0051603(proteolysis involved in cellular protein catabolic process);GO:0036021(endolysosome lumen);GO:0001957(intramembranous ossification);GO:0045453(bone resorption);GO:0005737(cytoplasm)","04142(Lysosome);04210(Apoptosis);04620(Toll-like receptor signaling pathway);04380(Osteoclast differentiation);05323(Rheumatoid arthritis)","K01371","EC:3.4.22.38","cathepsin K [Source:HGNC Symbol;Acc:HGNC:2536]",{"v":1.611732,"d":"1.61"},{"v":1.174674,"d":"1.17"},{"v":1.37206748425521,"d":"1.37"},{"v":0.456351441281869,"d":"0.46"},{"v":0.721896242831264,"d":"0.72"},{"v":0.91541700835671,"d":"0.92"},"up","no"]
[53217,0,"chr14","+",23321457,23326163,"ENST00000397276",6,2768,"MSTRG.4191","PABPN1","GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0006397(mRNA processing);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016607(nuclear speck);GO:0030529(intracellular ribonucleoprotein complex);GO:0005515(protein binding);GO:0005654(nucleoplasm);GO:0071222(cellular response to lipopolysaccharide);GO:1904247(positive regulation of polynucleotide adenylyltransferase activity);GO:0006369(termination of RNA polymerase II transcription);GO:0031124(mRNA 3'-end processing);GO:0006936(muscle contraction);GO:0000165(MAPK cascade);GO:0000398(mRNA splicing, via spliceosome);GO:0006396(RNA processing);GO:0070063(RNA polymerase binding);GO:0042405(nuclear inclusion body);GO:0016973(poly(A)+ mRNA export from nucleus);GO:0046778(modification by virus of host mRNA processing)","03015(mRNA surveillance pathway);05164(Influenza A)","NA","NA","poly(A) binding protein nuclear 1 [Source:HGNC Symbol;Acc:HGNC:8565]",{"v":4.380666,"d":"4.38"},{"v":4.474236,"d":"4.47"},{"v":0.97908693238354,"d":"0.98"},{"v":-0.0304911335766512,"d":"-0.03"},{"v":0.728976428280394,"d":"0.73"},{"v":0.919081590494581,"d":"0.92"},"down","no"]
[46514,0,"chr12","+",109999523,110039763,"ENST00000261739",15,4148,"MSTRG.3704","ANKRD13A","GO:0016020(membrane);GO:0005886(plasma membrane);GO:0005737(cytoplasm);GO:0005768(endosome);GO:0005770(late endosome)","NA","NA","NA","ankyrin repeat domain 13A [Source:HGNC Symbol;Acc:HGNC:21268]",{"v":13.477558,"d":"13.48"},{"v":13.671667,"d":"13.67"},{"v":0.98580209714002,"d":"0.99"},{"v":-0.0206300447665448,"d":"-0.02"},{"v":0.735726583355175,"d":"0.74"},{"v":0.921250725402833,"d":"0.92"},"down","no"]
[160533,0,"chr5","-",157786289,157859175,"ENST00000411809",12,3440,"MSTRG.12497","CLINT1","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0016192(vesicle-mediated transport);GO:0043231(intracellular membrane-bounded organelle);GO:0005654(nucleoplasm);GO:0005794(Golgi apparatus);GO:0005515(protein binding);GO:0048471(perinuclear region of cytoplasm);GO:0031410(cytoplasmic vesicle);GO:0008289(lipid binding);GO:0005829(cytosol);GO:0045296(cadherin binding);GO:0006897(endocytosis);GO:0030136(clathrin-coated vesicle);GO:0030276(clathrin binding);GO:0048268(clathrin coat assembly)","NA","NA","NA","clathrin interactor 1 [Source:HGNC Symbol;Acc:HGNC:23186]",{"v":9.393158,"d":"9.39"},{"v":7.065193,"d":"7.07"},{"v":1.32949772214291,"d":"1.33"},{"v":0.410881305397198,"d":"0.41"},{"v":0.749138180791563,"d":"0.75"},{"v":0.925860116264034,"d":"0.93"},"up","no"]
[131070,0,"chr22","+",37658727,37666934,"ENST00000215904",2,2010,"MSTRG.10437","PDXP","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0046872(metal ion binding);GO:0016787(hydrolase activity);GO:0008152(metabolic process);GO:0016791(phosphatase activity);GO:0005829(cytosol);GO:0016311(dephosphorylation);GO:0005886(plasma membrane);GO:0004721(phosphoprotein phosphatase activity);GO:0005856(cytoskeleton);GO:0042995(cell projection);GO:0005515(protein binding);GO:0000287(magnesium ion binding);GO:0030496(midbody);GO:0030027(lamellipodium);GO:0070062(extracellular exosome);GO:0032154(cleavage furrow);GO:0032587(ruffle membrane);GO:0098519(nucleotide phosphatase activity, acting on free nucleotides);GO:0006470(protein dephosphorylation);GO:0015629(actin cytoskeleton);GO:0007088(regulation of mitotic nuclear division);GO:0032465(regulation of cytokinesis);GO:0070938(contractile ring);GO:0031258(lamellipodium membrane);GO:0030836(positive regulation of actin filament depolymerization);GO:0031247(actin rod assembly);GO:0071318(cellular response to ATP);GO:0004647(phosphoserine phosphatase activity);GO:0033883(pyridoxal phosphatase activity);GO:0031072(heat shock protein binding);GO:0032361(pyridoxal phosphate catabolic process)","00750(Vitamin B6 metabolism)","K07758","EC:3.1.3.74","pyridoxal phosphatase [Source:HGNC Symbol;Acc:HGNC:30259]",{"v":1.899736,"d":"1.90"},{"v":1.421822,"d":"1.42"},{"v":1.33612786973334,"d":"1.34"},{"v":0.418058082813841,"d":"0.42"},{"v":0.754808064642868,"d":"0.75"},{"v":0.927722582764061,"d":"0.93"},"up","no"]
[1163,0,"chr1","+",6785324,7769706,"ENST00000303635",23,8444,"MSTRG.106","CAMTA1","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005730(nucleolus);GO:0005829(cytosol);GO:0006366(transcription from RNA polymerase II promoter);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0001077(transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0043565(sequence-specific DNA binding);GO:0050885(neuromuscular process controlling balance)","NA","NA","NA","calmodulin binding transcription activator 1 [Source:HGNC Symbol;Acc:HGNC:18806]",{"v":0.281715,"d":"0.28"},{"v":0.284236,"d":"0.28"},{"v":0.991130609774976,"d":"0.99"},{"v":-0.0128529086576567,"d":"-0.01"},{"v":0.762766952803542,"d":"0.76"},{"v":0.931078232408277,"d":"0.93"},"down","no"]
[107095,0,"chr2","+",6877665,6898239,"ENST00000382040",6,3519,"ENSG00000134321","RSAD2","GO:0003824(catalytic activity);GO:0051536(iron-sulfur cluster binding);GO:0016020(membrane);GO:0046872(metal ion binding);GO:0005783(endoplasmic reticulum);GO:0005743(mitochondrial inner membrane);GO:0005794(Golgi apparatus);GO:0001650(fibrillar center);GO:0005789(endoplasmic reticulum membrane);GO:0005739(mitochondrion);GO:0005515(protein binding);GO:0005741(mitochondrial outer membrane);GO:0051539(4 iron, 4 sulfur cluster binding);GO:0051607(defense response to virus);GO:0002376(immune system process);GO:0045087(innate immune response);GO:0009615(response to virus);GO:0045071(negative regulation of viral genome replication);GO:0016032(viral process);GO:0005811(lipid particle);GO:0043621(protein self-association);GO:0060337(type I interferon signaling pathway);GO:0034165(positive regulation of toll-like receptor 9 signaling pathway);GO:2000553(positive regulation of T-helper 2 cell cytokine production);GO:0050709(negative regulation of protein secretion);GO:0034157(positive regulation of toll-like receptor 7 signaling pathway);GO:0035710(CD4-positive, alpha-beta T cell activation);GO:0043367(CD4-positive, alpha-beta T cell differentiation)","05164(Influenza A)","K15045","NA","radical S-adenosyl methionine domain containing 2 [Source:HGNC Symbol;Acc:HGNC:30908]",{"v":3.033042,"d":"3.03"},{"v":2.305574,"d":"2.31"},{"v":1.31552576495051,"d":"1.32"},{"v":0.395639504377858,"d":"0.40"},{"v":0.768319716864316,"d":"0.77"},{"v":0.93267107404885,"d":"0.93"},"up","no"]
[123618,0,"chr20","+",38033546,38092366,"ENST00000373433",7,3874,"MSTRG.9735","RPRD1B","GO:0005634(nucleus);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0005813(centrosome);GO:0005515(protein binding);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0008284(positive regulation of cell proliferation);GO:0042795(snRNA transcription from RNA polymerase II promoter);GO:0000993(RNA polymerase II core binding);GO:0016591(DNA-directed RNA polymerase II, holoenzyme);GO:0010564(regulation of cell cycle process);GO:0070940(dephosphorylation of RNA polymerase II C-terminal domain)","NA","NA","NA","regulation of nuclear pre-mRNA domain containing 1B [Source:HGNC Symbol;Acc:HGNC:16209]",{"v":6.145085,"d":"6.15"},{"v":4.694283,"d":"4.69"},{"v":1.30905720852364,"d":"1.31"},{"v":0.388528147435842,"d":"0.39"},{"v":0.774857909722107,"d":"0.77"},{"v":0.935412621221125,"d":"0.94"},"up","no"]
[80738,0,"chr17","-",19906227,19977679,"ENST00000395536",14,1815,"ENSG00000108599","AKAP10","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005829(cytosol);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0005886(plasma membrane);GO:0005739(mitochondrion);GO:0008104(protein localization);GO:0007165(signal transduction);GO:0007596(blood coagulation)","NA","NA","NA","A-kinase anchoring protein 10 [Source:HGNC Symbol;Acc:HGNC:368]",{"v":0.526921,"d":"0.53"},{"v":0.530233,"d":"0.53"},{"v":0.993753689415785,"d":"0.99"},{"v":-0.0090397834349804,"d":"-0.01"},{"v":0.783238027646127,"d":"0.78"},{"v":0.939317042148721,"d":"0.94"},"down","no"]
[30858,0,"chr11","-",64764606,64778786,"ENST00000334944",14,3094,"MSTRG.2520","SF1","GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0006397(mRNA processing);GO:0008380(RNA splicing);GO:0005634(nucleus);GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0005654(nucleoplasm);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0005840(ribosome);GO:0005515(protein binding);GO:0005681(spliceosomal complex);GO:0045131(pre-mRNA branch point binding);GO:0000398(mRNA splicing, via spliceosome);GO:1903507(negative regulation of nucleic acid-templated transcription);GO:0042802(identical protein binding);GO:0003714(transcription corepressor activity);GO:0000245(spliceosomal complex assembly);GO:0000389(mRNA 3'-splice site recognition);GO:0030238(male sex determination);GO:0030575(nuclear body organization);GO:0033327(Leydig cell differentiation);GO:0048662(negative regulation of smooth muscle cell proliferation);GO:0050810(regulation of steroid biosynthetic process);GO:0016604(nuclear body)","NA","NA","NA","splicing factor 1 [Source:HGNC Symbol;Acc:HGNC:12950]",{"v":1.434074,"d":"1.43"},{"v":1.417306,"d":"1.42"},{"v":1.01183089608031,"d":"1.01"},{"v":0.0169681973723851,"d":"0.02"},{"v":0.789334708575813,"d":"0.79"},{"v":0.941435429648495,"d":"0.94"},"up","no"]
[91570,0,"chr18","-",31829173,31943100,"ENST00000283351",29,6226,"MSTRG.7459","TRAPPC8","GO:0006810(transport);GO:0005794(Golgi apparatus);GO:0043547(positive regulation of GTPase activity);GO:0005515(protein binding);GO:0016192(vesicle-mediated transport);GO:0005829(cytosol);GO:0017112(Rab guanyl-nucleotide exchange factor activity);GO:0061024(membrane organization);GO:0034497(protein localization to pre-autophagosomal structure);GO:0044804(nucleophagy);GO:0000407(pre-autophagosomal structure);GO:0031410(cytoplasmic vesicle);GO:0006888(ER to Golgi vesicle-mediated transport);GO:0007030(Golgi organization);GO:0030008(TRAPP complex);GO:0030242(pexophagy);GO:1990072(TRAPPIII protein complex)","NA","NA","NA","trafficking protein particle complex 8 [Source:HGNC Symbol;Acc:HGNC:29169]",{"v":8.994031,"d":"8.99"},{"v":6.961927,"d":"6.96"},{"v":1.29188815108231,"d":"1.29"},{"v":0.36948116998234,"d":"0.37"},{"v":0.796594052490282,"d":"0.80"},{"v":0.94390113667181,"d":"0.94"},"up","no"]
[186200,0,"chr8","+",102239394,102252174,"ENST00000520820",3,800,"ENSG00000246263","UBR5-AS1","NA","NA","NA","NA","UBR5 antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:51661]",{"v":1.413813,"d":"1.41"},{"v":1.395025,"d":"1.40"},{"v":1.01346785899894,"d":"1.01"},{"v":0.0193003360686424,"d":"0.02"},{"v":0.810913469270636,"d":"0.81"},{"v":0.949263826900576,"d":"0.95"},"up","no"]
[52736,0,"chr14","+",21723713,21724321,"ENST00000390425",2,519,"ENSG00000211777","TRAV3","NA","NA","NA","NA","T-cell receptor alpha variable 3 (gene/pseudogene) [Source:HGNC Symbol;Acc:HGNC:12128]",{"v":2.309321,"d":"2.31"},{"v":1.77445,"d":"1.77"},{"v":1.3014291752374,"d":"1.30"},{"v":0.38009680132017,"d":"0.38"},{"v":0.818897516218117,"d":"0.82"},{"v":0.951859037547005,"d":"0.95"},"up","no"]
[44108,0,"chr12","-",68154768,68159747,"ENST00000229135",4,1218,"ENSG00000111537","IFNG","GO:0008284(positive regulation of cell proliferation);GO:0042531(positive regulation of tyrosine phosphorylation of STAT protein);GO:0030857(negative regulation of epithelial cell differentiation);GO:0048662(negative regulation of smooth muscle cell proliferation);GO:0005576(extracellular region);GO:0006955(immune response);GO:0005125(cytokine activity);GO:0005615(extracellular space);GO:0051607(defense response to virus);GO:0010508(positive regulation of autophagy);GO:0010628(positive regulation of gene expression);GO:0040008(regulation of growth);GO:0035722(interleukin-12-mediated signaling pathway);GO:0010629(negative regulation of gene expression);GO:0032834(positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation involved in immune response);GO:0032700(negative regulation of interleukin-17 production);GO:0007166(cell surface receptor signaling pathway);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0006915(apoptotic process);GO:0006928(movement of cell or subcellular component);GO:1903543(positive regulation of exosomal secretion);GO:0060333(interferon-gamma-mediated signaling pathway);GO:0060334(regulation of interferon-gamma-mediated signaling pathway);GO:0045672(positive regulation of osteoclast differentiation);GO:0097191(extrinsic apoptotic signaling pathway);GO:0002250(adaptive immune response);GO:0045429(positive regulation of nitric oxide biosynthetic process);GO:0051044(positive regulation of membrane protein ectodomain proteolysis);GO:0090004(positive regulation of establishment of protein localization to plasma membrane);GO:0000060(protein import into nucleus, translocation);GO:0007050(cell cycle arrest);GO:0050796(regulation of insulin secretion);GO:0060557(positive regulation of vitamin D biosynthetic process);GO:0060559(positive regulation of calcidiol 1-monooxygenase activity);GO:0006959(humoral immune response);GO:0033141(positive regulation of peptidyl-serine phosphorylation of STAT protein);GO:0005133(interferon-gamma receptor binding);GO:0001781(neutrophil apoptotic process);GO:0001934(positive regulation of protein phosphorylation);GO:0002026(regulation of the force of heart contraction);GO:0002302(CD8-positive, alpha-beta T cell differentiation involved in immune response);GO:0006355(regulation of transcription, DNA-templated);GO:0006925(inflammatory cell apoptotic process);GO:0008285(negative regulation of cell proliferation);GO:0009615(response to virus);GO:0010634(positive regulation of epithelial cell migration);GO:0010835(regulation of protein ADP-ribosylation);GO:0019882(antigen processing and presentation);GO:0030593(neutrophil chemotaxis);GO:0030968(endoplasmic reticulum unfolded protein response);GO:0031334(positive regulation of protein complex assembly);GO:0031642(negative regulation of myelination);GO:0032224(positive regulation of synaptic transmission, cholinergic);GO:0032735(positive regulation of interleukin-12 production);GO:0032747(positive regulation of interleukin-23 production);GO:0032760(positive regulation of tumor necrosis factor production);GO:0033160(positive regulation of protein import into nucleus, translocation);GO:0034393(positive regulation of smooth muscle cell apoptotic process);GO:0042102(positive regulation of T cell proliferation);GO:0042493(response to drug);GO:0042742(defense response to bacterium);GO:0042832(defense response to protozoan);GO:0043065(positive regulation of apoptotic process);GO:0044130(negative regulation of growth of symbiont in host);GO:0044146(negative regulation of growth of symbiont involved in interaction with host);GO:0045080(positive regulation of chemokine biosynthetic process);GO:0045084(positive regulation of interleukin-12 biosynthetic process);GO:0045348(positive regulation of MHC class II biosynthetic process);GO:0045410(positive regulation of interleukin-6 biosynthetic process);GO:0045589(regulation of regulatory T cell differentiation);GO:0045666(positive regulation of neuron differentiation);GO:0045785(positive regulation of cell adhesion);GO:0045892(negative regulation of transcription, DNA-templated);GO:0045893(positive regulation of transcription, DNA-templated);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0048147(negative regulation of fibroblast proliferation);GO:0048304(positive regulation of isotype switching to IgG isotypes);GO:0050691(regulation of defense response to virus by host);GO:0050718(positive regulation of interleukin-1 beta secretion);GO:0050776(regulation of immune response);GO:0050852(T cell receptor signaling pathway);GO:0050954(sensory perception of mechanical stimulus);GO:0051712(positive regulation of killing of cells of other organism);GO:0060251(regulation of glial cell proliferation);GO:0060550(positive regulation of fructose 1,6-bisphosphate 1-phosphatase activity);GO:0060552(positive regulation of fructose 1,6-bisphosphate metabolic process);GO:0071222(cellular response to lipopolysaccharide);GO:0071351(cellular response to interleukin-18);GO:0071902(positive regulation of protein serine/threonine kinase activity);GO:0072125(negative regulation of glomerular mesangial cell proliferation);GO:0090312(positive regulation of protein deacetylation);GO:0098908(regulation of neuronal action potential);GO:1904798(positive regulation of core promoter binding);GO:2000309(positive regulation of tumor necrosis factor (ligand) superfamily member 11 production);GO:2000345(regulation of hepatocyte proliferation);GO:0005737(cytoplasm);GO:0009897(external side of plasma membrane);GO:0043005(neuron projection);GO:0043204(perikaryon)","03050(Proteasome);04350(TGF-beta signaling pathway);04630(Jak-STAT signaling pathway);04066(HIF-1 signaling pathway);04060(Cytokine-cytokine receptor interaction);04217(Necroptosis);04650(Natural killer cell mediated cytotoxicity);04612(Antigen processing and presentation);04660(T cell receptor signaling pathway);04658(Th1 and Th2 cell differentiation);04659(Th17 cell differentiation);04657(IL-17 signaling pathway);04380(Osteoclast differentiation);05200(Pathways in cancer);05322(Systemic lupus erythematosus);05323(Rheumatoid arthritis);05321(Inflammatiory bowel disease (IBD));05330(Allograft rejection);05332(Graft-versus-host disease);05418(Fluid shear stress and atherosclerosis);04940(Type I diabetes mellitus);05132(Salmonella infection);05152(Tuberculosis);05162(Measles);05164(Influenza A);05168(Herpes simplex infection);05169(Epstein-Barr virus infection);05146(Amoebiasis);05144(Malaria);05145(Toxoplasmosis);05140(Leishmaniasis);05142(Chagas disease (American trypanosomiasis));05143(African trypanosomiasis)","K04687","NA","interferon gamma [Source:HGNC Symbol;Acc:HGNC:5438]",{"v":1.870997,"d":"1.87"},{"v":1.809955,"d":"1.81"},{"v":1.03372570036272,"d":"1.03"},{"v":0.0478534165760026,"d":"0.05"},{"v":0.824572216145934,"d":"0.82"},{"v":0.954021809805049,"d":"0.95"},"up","no"]
[115418,0,"chr2","+",152717914,152761253,"ENST00000326446",4,2805,"MSTRG.9174","ARL6IP6","GO:0016020(membrane);GO:0016021(integral component of membrane)","NA","NA","NA","ADP ribosylation factor like GTPase 6 interacting protein 6 [Source:HGNC Symbol;Acc:HGNC:24048]",{"v":5.371675,"d":"5.37"},{"v":4.235546,"d":"4.24"},{"v":1.26823672792126,"d":"1.27"},{"v":0.342824062765632,"d":"0.34"},{"v":0.830400581327353,"d":"0.83"},{"v":0.955620481714057,"d":"0.96"},"up","no"]
[12298,0,"chr1","-",157676482,157700857,"ENST00000368184",15,4725,"MSTRG.1097","FCRL3","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005886(plasma membrane)","NA","NA","NA","Fc receptor like 3 [Source:HGNC Symbol;Acc:HGNC:18506]",{"v":6.834526,"d":"6.83"},{"v":5.41739,"d":"5.42"},{"v":1.26159017534274,"d":"1.26"},{"v":0.335243330269993,"d":"0.34"},{"v":0.838109235145218,"d":"0.84"},{"v":0.958349115296786,"d":"0.96"},"up","no"]
[108322,0,"chr2","-",27650812,27663809,"ENST00000337768",6,4488,"MSTRG.8604","SUPT7L","GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0004402(histone acetyltransferase activity);GO:0003713(transcription coactivator activity);GO:0005515(protein binding);GO:0043966(histone H3 acetylation);GO:0030914(STAGA complex);GO:0051457(maintenance of protein location in nucleus)","NA","NA","NA","SPT7 like, STAGA complex gamma subunit [Source:HGNC Symbol;Acc:HGNC:30632]",{"v":3.223374,"d":"3.22"},{"v":3.07157,"d":"3.07"},{"v":1.04942228241583,"d":"1.05"},{"v":0.0695953282070745,"d":"0.07"},{"v":0.843873766115465,"d":"0.84"},{"v":0.959953168518154,"d":"0.96"},"up","no"]
[92092,0,"chr18","-",45907865,45967274,"ENST00000587974",24,4457,"ENSG00000152223","EPG5","GO:0006914(autophagy);GO:0005737(cytoplasm);GO:0097352(autophagosome maturation);GO:0032456(endocytic recycling)","NA","NA","NA","ectopic P-granules autophagy protein 5 homolog [Source:HGNC Symbol;Acc:HGNC:29331]",{"v":0.93043,"d":"0.93"},{"v":0.738437,"d":"0.74"},{"v":1.25999916038877,"d":"1.26"},{"v":0.333422772373314,"d":"0.33"},{"v":0.849951146709882,"d":"0.85"},{"v":0.961661409421172,"d":"0.96"},"up","no"]
[187877,0,"chr8","+",143269358,143276931,"ENST00000523522",3,1297,"ENSG00000250571","GLI4","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0006355(regulation of transcription, DNA-templated);GO:0003674(molecular_function);GO:0008150(biological_process)","NA","NA","NA","GLI family zinc finger 4 [Source:HGNC Symbol;Acc:HGNC:4320]",{"v":0.697447,"d":"0.70"},{"v":0.675375,"d":"0.68"},{"v":1.03268110309088,"d":"1.03"},{"v":0.0463948117846678,"d":"0.05"},{"v":0.85848030777147,"d":"0.86"},{"v":0.965030471843601,"d":"0.97"},"up","no"]
[137769,0,"chr3","-",64010555,64023472,"ENST00000492933",9,1495,"MSTRG.11035","PSMD6","GO:0005515(protein binding);GO:0006508(proteolysis);GO:0000502(proteasome complex);GO:0038095(Fc-epsilon receptor signaling pathway);GO:0005576(extracellular region);GO:0030234(enzyme regulator activity);GO:0043161(proteasome-mediated ubiquitin-dependent protein catabolic process);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0000165(MAPK cascade);GO:0000209(protein polyubiquitination);GO:0002223(stimulatory C-type lectin receptor signaling pathway);GO:0002479(antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent);GO:0006521(regulation of cellular amino acid metabolic process);GO:0010972(negative regulation of G2/M transition of mitotic cell cycle);GO:0016579(protein deubiquitination);GO:0031145(anaphase-promoting complex-dependent catabolic process);GO:0031146(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process);GO:0033209(tumor necrosis factor-mediated signaling pathway);GO:0038061(NIK/NF-kappaB signaling);GO:0043488(regulation of mRNA stability);GO:0043687(post-translational protein modification);GO:0050852(T cell receptor signaling pathway);GO:0051437(positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition);GO:0055085(transmembrane transport);GO:0060071(Wnt signaling pathway, planar cell polarity pathway);GO:0061418(regulation of transcription from RNA polymerase II promoter in response to hypoxia);GO:0090090(negative regulation of canonical Wnt signaling pathway);GO:0090263(positive regulation of canonical Wnt signaling pathway);GO:1902036(regulation of hematopoietic stem cell differentiation);GO:0016887(ATPase activity);GO:0043312(neutrophil degranulation);GO:0051436(negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle);GO:0022624(proteasome accessory complex);GO:0034774(secretory granule lumen);GO:1904813(ficolin-1-rich granule lumen);GO:0005838(proteasome regulatory particle);GO:0050790(regulation of catalytic activity)","03050(Proteasome);05169(Epstein-Barr virus infection)","K03037","NA","proteasome 26S subunit, non-ATPase 6 [Source:HGNC Symbol;Acc:HGNC:9564]",{"v":1.13686,"d":"1.14"},{"v":0.907971,"d":"0.91"},{"v":1.25208844775879,"d":"1.25"},{"v":0.324336478113925,"d":"0.32"},{"v":0.871490115099003,"d":"0.87"},{"v":0.968736957134886,"d":"0.97"},"up","no"]
[110116,0,"chr2","-",61868125,61888671,"ENST00000544079",13,2261,"MSTRG.8728","CCT4","GO:0003723(RNA binding);GO:0005737(cytoplasm);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0006457(protein folding);GO:0005856(cytoskeleton);GO:0042995(cell projection);GO:0005515(protein binding);GO:0042470(melanosome);GO:0005874(microtubule);GO:0051082(unfolded protein binding);GO:0005815(microtubule organizing center);GO:0061077(chaperone-mediated protein folding);GO:0070062(extracellular exosome);GO:0050821(protein stabilization);GO:0032212(positive regulation of telomere maintenance via telomerase);GO:0051973(positive regulation of telomerase activity);GO:0005813(centrosome);GO:1904851(positive regulation of establishment of protein localization to telomere);GO:1904874(positive regulation of telomerase RNA localization to Cajal body);GO:0044183(protein binding involved in protein folding);GO:0006458('de novo' protein folding);GO:0090666(scaRNA localization to Cajal body);GO:1904871(positive regulation of protein localization to Cajal body);GO:0005832(chaperonin-containing T-complex);GO:0007339(binding of sperm to zona pellucida);GO:1901998(toxin transport);GO:0002199(zona pellucida receptor complex);GO:0044297(cell body)","NA","NA","NA","chaperonin containing TCP1 subunit 4 [Source:HGNC Symbol;Acc:HGNC:1617]",{"v":1.325203,"d":"1.33"},{"v":1.072133,"d":"1.07"},{"v":1.23604347594935,"d":"1.24"},{"v":0.305729488738583,"d":"0.31"},{"v":0.876919094495284,"d":"0.88"},{"v":0.969845463999144,"d":"0.97"},"up","no"]
[189148,0,"chr9","-",14611071,14693471,"ENST00000380916",10,9160,"ENSG00000175893","ZDHHC21","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016740(transferase activity);GO:0005794(Golgi apparatus);GO:0016746(transferase activity, transferring acyl groups);GO:0019706(protein-cysteine S-palmitoyltransferase activity);GO:0005886(plasma membrane);GO:0000139(Golgi membrane);GO:0050999(regulation of nitric-oxide synthase activity);GO:0016409(palmitoyltransferase activity);GO:0018345(protein palmitoylation);GO:0018230(peptidyl-L-cysteine S-palmitoylation);GO:0001942(hair follicle development);GO:0048733(sebaceous gland development)","NA","NA","NA","zinc finger DHHC-type containing 21 [Source:HGNC Symbol;Acc:HGNC:20750]",{"v":0.895693,"d":"0.90"},{"v":0.836058,"d":"0.84"},{"v":1.07132878340976,"d":"1.07"},{"v":0.0994013011921837,"d":"0.10"},{"v":0.880951335887928,"d":"0.88"},{"v":0.971207211106178,"d":"0.97"},"up","no"]
[31509,0,"chr11","-",65996545,66002156,"ENST00000526451",6,2761,"MSTRG.2573","EIF1AD","GO:0003723(RNA binding);GO:0005634(nucleus);GO:0003743(translation initiation factor activity);GO:0006412(translation);GO:0006413(translational initiation);GO:0005515(protein binding)","NA","NA","NA","eukaryotic translation initiation factor 1A domain containing [Source:HGNC Symbol;Acc:HGNC:28147]",{"v":1.208302,"d":"1.21"},{"v":0.975721,"d":"0.98"},{"v":1.23836834504946,"d":"1.24"},{"v":0.308440499153222,"d":"0.31"},{"v":0.889258139704056,"d":"0.89"},{"v":0.972586813759452,"d":"0.97"},"up","no"]
[166721,0,"chr6","-",53267398,53349179,"ENST00000370918",9,3081,"MSTRG.13091","ELOVL5","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005783(endoplasmic reticulum);GO:0016740(transferase activity);GO:0006629(lipid metabolic process);GO:0005789(endoplasmic reticulum membrane);GO:0009922(fatty acid elongase activity);GO:0102336(3-oxo-arachidoyl-CoA synthase activity);GO:0102337(3-oxo-cerotoyl-CoA synthase activity);GO:0102338(3-oxo-lignoceronyl-CoA synthase activity);GO:0006631(fatty acid metabolic process);GO:0006633(fatty acid biosynthetic process);GO:0006636(unsaturated fatty acid biosynthetic process);GO:0019367(fatty acid elongation, saturated fatty acid);GO:0034626(fatty acid elongation, polyunsaturated fatty acid);GO:0042761(very long-chain fatty acid biosynthetic process);GO:0042995(cell projection);GO:0034625(fatty acid elongation, monounsaturated fatty acid);GO:0035338(long-chain fatty-acyl-CoA biosynthetic process);GO:0030425(dendrite);GO:0005515(protein binding);GO:0030148(sphingolipid biosynthetic process);GO:0030176(integral component of endoplasmic reticulum membrane);GO:0036109(alpha-linolenic acid metabolic process);GO:0043025(neuronal cell body);GO:0043651(linoleic acid metabolic process);GO:0045723(positive regulation of fatty acid biosynthetic process);GO:0097447(dendritic tree)","00062(Fatty acid elongation);01040(Biosynthesis of unsaturated fatty acids)","K10244","EC:2.3.1.199","ELOVL fatty acid elongase 5 [Source:HGNC Symbol;Acc:HGNC:21308]",{"v":2.398437,"d":"2.40"},{"v":1.961982,"d":"1.96"},{"v":1.22245616932265,"d":"1.22"},{"v":0.289782738850759,"d":"0.29"},{"v":0.896029811453032,"d":"0.90"},{"v":0.974264405133941,"d":"0.97"},"up","no"]
[181496,0,"chr8","-",16139319,16192659,"ENST00000381998",9,2826,"ENSG00000038945","MSR1","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005515(protein binding);GO:0005581(collagen trimer);GO:0005044(scavenger receptor activity);GO:0006898(receptor-mediated endocytosis);GO:0005886(plasma membrane);GO:0006897(endocytosis);GO:0005887(integral component of plasma membrane);GO:0030666(endocytic vesicle membrane);GO:0010744(positive regulation of macrophage derived foam cell differentiation);GO:0006911(phagocytosis, engulfment);GO:0097242(amyloid-beta clearance);GO:0030169(low-density lipoprotein particle binding);GO:0034362(low-density lipoprotein particle);GO:0010886(positive regulation of cholesterol storage);GO:0030301(cholesterol transport);GO:0010629(negative regulation of gene expression);GO:0034381(plasma lipoprotein particle clearance);GO:0001540(amyloid-beta binding);GO:0042953(lipoprotein transport);GO:0071407(cellular response to organic cyclic compound);GO:0005829(cytosol);GO:0031410(cytoplasmic vesicle)","04145(Phagosome)","K06558","NA","macrophage scavenger receptor 1 [Source:HGNC Symbol;Acc:HGNC:7376]",{"v":0.431509,"d":"0.43"},{"v":0.35021,"d":"0.35"},{"v":1.23214357100026,"d":"1.23"},{"v":0.301170370563768,"d":"0.30"},{"v":0.903267528651553,"d":"0.90"},{"v":0.977054444261814,"d":"0.98"},"up","no"]
[182423,0,"chr8","-",27284887,27311319,"ENST00000305364",6,4229,"MSTRG.14255","TRIM35","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0005622(intracellular);GO:0006915(apoptotic process);GO:0045087(innate immune response);GO:0003674(molecular_function);GO:0043065(positive regulation of apoptotic process);GO:0045930(negative regulation of mitotic cell cycle);GO:1902187(negative regulation of viral release from host cell)","NA","NA","NA","tripartite motif containing 35 [Source:HGNC Symbol;Acc:HGNC:16285]",{"v":4.143468,"d":"4.14"},{"v":3.786477,"d":"3.79"},{"v":1.09428051457859,"d":"1.09"},{"v":0.129982614835902,"d":"0.13"},{"v":0.916850285499191,"d":"0.92"},{"v":0.980848021224597,"d":"0.98"},"up","no"]
[61145,0,"chr15","+",40382721,40394245,"ENST00000249776",9,1714,"ENSG00000128944","KNSTRN","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0051301(cell division);GO:0005694(chromosome);GO:0015630(microtubule cytoskeleton);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0007049(cell cycle);GO:0007059(chromosome segregation);GO:0005874(microtubule);GO:0000776(kinetochore);GO:0000922(spindle pole);GO:0007051(spindle organization);GO:0000775(chromosome, centromeric region);GO:0000777(condensed chromosome kinetochore);GO:0051988(regulation of attachment of spindle microtubules to kinetochore);GO:0000070(mitotic sister chromatid segregation);GO:0072686(mitotic spindle);GO:0035371(microtubule plus-end)","NA","NA","NA","kinetochore localized astrin/SPAG5 binding protein [Source:HGNC Symbol;Acc:HGNC:30767]",{"v":0.685878,"d":"0.69"},{"v":0.636505,"d":"0.64"},{"v":1.07756891147752,"d":"1.08"},{"v":0.107780133878523,"d":"0.11"},{"v":0.924621652120871,"d":"0.92"},{"v":0.98341377329577,"d":"0.98"},"up","no"]
[91014,0,"chr18","+",13730438,13760067,"ENST00000589866",11,1879,"ENSG00000101654","RNMT","GO:0005634(nucleus);GO:0003723(RNA binding);GO:0006397(mRNA processing);GO:0005654(nucleoplasm);GO:0008168(methyltransferase activity);GO:0016740(transferase activity);GO:0032259(methylation);GO:0001650(fibrillar center);GO:0005515(protein binding);GO:0005845(mRNA cap binding complex);GO:0006370(7-methylguanosine mRNA capping);GO:0004482(mRNA (guanine-N7-)-methyltransferase activity);GO:0106005(RNA 5'-cap (guanine-N7)-methylation);GO:0006366(transcription from RNA polymerase II promoter);GO:0043235(receptor complex);GO:0031533(mRNA cap methyltransferase complex);GO:1990830(cellular response to leukemia inhibitory factor)","03015(mRNA surveillance pathway)","NA","NA","RNA guanine-7 methyltransferase [Source:HGNC Symbol;Acc:HGNC:10075]",{"v":1.4929,"d":"1.49"},{"v":1.239142,"d":"1.24"},{"v":1.20478524656577,"d":"1.20"},{"v":0.268776008425331,"d":"0.27"},{"v":0.930793541117554,"d":"0.93"},{"v":0.98515953100311,"d":"0.99"},"up","no"]
[30634,0,"chr11","+",64206734,64223886,"ENST00000345728",15,2481,"MSTRG.2509","FERMT3","GO:0016020(membrane);GO:0007155(cell adhesion);GO:0042995(cell projection);GO:0030054(cell junction);GO:0007229(integrin-mediated signaling pathway);GO:0005576(extracellular region);GO:0070062(extracellular exosome);GO:0002102(podosome);GO:0030335(positive regulation of cell migration);GO:0070527(platelet aggregation);GO:0002576(platelet degranulation);GO:0005178(integrin binding);GO:0031093(platelet alpha granule lumen);GO:0033622(integrin activation);GO:0033632(regulation of cell-cell adhesion mediated by integrin);GO:0034446(substrate adhesion-dependent cell spreading);GO:0007159(leukocyte cell-cell adhesion)","04611(Platelet activation)","K17084","NA","fermitin family member 3 [Source:HGNC Symbol;Acc:HGNC:23151]",{"v":71.490562,"d":"71.49"},{"v":64.525612,"d":"64.53"},{"v":1.10794085920487,"d":"1.11"},{"v":0.147880873797738,"d":"0.15"},{"v":0.936227567719726,"d":"0.94"},{"v":0.986058713542577,"d":"0.99"},"up","no"]
[13356,0,"chr1","+",167630093,167706249,"ENST00000367854",7,3135,"MSTRG.1174","RCSD1","GO:0003009(skeletal muscle contraction);GO:0005884(actin filament);GO:0071474(cellular hyperosmotic response);GO:0051015(actin filament binding)","NA","NA","NA","RCSD domain containing 1 [Source:HGNC Symbol;Acc:HGNC:28310]",{"v":25.627022,"d":"25.63"},{"v":21.602325,"d":"21.60"},{"v":1.18630851077372,"d":"1.19"},{"v":0.246479245199055,"d":"0.25"},{"v":0.943973122092134,"d":"0.94"},{"v":0.988442030203413,"d":"0.99"},"up","no"]
[128651,0,"chr22","+",20021139,20065364,"ENST00000401833",9,1920,"MSTRG.10140","TANGO2","GO:0005794(Golgi apparatus)","NA","NA","NA","transport and golgi organization 2 homolog [Source:HGNC Symbol;Acc:HGNC:25439]",{"v":0.713441,"d":"0.71"},{"v":0.639648,"d":"0.64"},{"v":1.11536501325729,"d":"1.12"},{"v":0.15751592237786,"d":"0.16"},{"v":0.950109599665289,"d":"0.95"},{"v":0.990005101515161,"d":"0.99"},"up","no"]
[53073,0,"chr14","-",22946236,22957129,"ENST00000342454",9,1474,"MSTRG.4270","HAUS4","GO:0005737(cytoplasm);GO:0051301(cell division);GO:0005856(cytoskeleton);GO:0007049(cell cycle);GO:0005874(microtubule);GO:0007098(centrosome cycle);GO:0051225(spindle assembly);GO:0070652(HAUS complex);GO:0005813(centrosome);GO:0005815(microtubule organizing center);GO:0005819(spindle);GO:0003674(molecular_function);GO:0005829(cytosol);GO:0000086(G2/M transition of mitotic cell cycle);GO:0010389(regulation of G2/M transition of mitotic cell cycle);GO:0097711(ciliary basal body docking)","NA","NA","NA","HAUS augmin like complex subunit 4 [Source:HGNC Symbol;Acc:HGNC:20163]",{"v":1.518405,"d":"1.52"},{"v":1.283425,"d":"1.28"},{"v":1.18308822097123,"d":"1.18"},{"v":0.242557657119963,"d":"0.24"},{"v":0.957155736186464,"d":"0.96"},{"v":0.991133949173224,"d":"0.99"},"up","no"]
[160971,0,"chr5","-",170270500,170297727,"ENST00000519594",7,858,"MSTRG.12527","LCP2","GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005515(protein binding);GO:0038095(Fc-epsilon receptor signaling pathway);GO:0035556(intracellular signal transduction);GO:0050852(T cell receptor signaling pathway);GO:0006955(immune response);GO:0030168(platelet activation);GO:0007169(transmembrane receptor protein tyrosine kinase signaling pathway);GO:0045860(positive regulation of protein kinase activity);GO:0044853(plasma membrane raft);GO:0045576(mast cell activation);GO:0050663(cytokine secretion);GO:0005911(cell-cell junction);GO:0036398(TCR signalosome)","04015(Rap1 signaling pathway);04611(Platelet activation);04650(Natural killer cell mediated cytotoxicity);04660(T cell receptor signaling pathway);04664(Fc epsilon RI signaling pathway);04380(Osteoclast differentiation)","NA","NA","lymphocyte cytosolic protein 2 [Source:HGNC Symbol;Acc:HGNC:6529]",{"v":3.077942,"d":"3.08"},{"v":2.617751,"d":"2.62"},{"v":1.1757963228741,"d":"1.18"},{"v":0.233638171204426,"d":"0.23"},{"v":0.9637641042117,"d":"0.96"},{"v":0.993857454309592,"d":"0.99"},"up","no"]
[110969,0,"chr2","+",71466702,71686648,"ENST00000410020",56,6657,"MSTRG.8818","DYSF","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0046872(metal ion binding);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0005815(microtubule organizing center);GO:0030659(cytoplasmic vesicle membrane);GO:0031410(cytoplasmic vesicle);GO:0005544(calcium-dependent phospholipid binding);GO:0005509(calcium ion binding);GO:0008289(lipid binding);GO:0005768(endosome);GO:0070062(extracellular exosome);GO:0042383(sarcolemma);GO:0005769(early endosome);GO:0005770(late endosome);GO:0030315(T-tubule);GO:0005543(phospholipid binding);GO:0006936(muscle contraction);GO:0030139(endocytic vesicle);GO:0001778(plasma membrane repair);GO:0006906(vesicle fusion);GO:0030027(lamellipodium)","NA","NA","NA","dysferlin [Source:HGNC Symbol;Acc:HGNC:3097]",{"v":0.161194,"d":"0.16"},{"v":0.136167,"d":"0.14"},{"v":1.18379636769555,"d":"1.18"},{"v":0.243420935205237,"d":"0.24"},{"v":0.9784765139443,"d":"0.98"},{"v":0.998038450697032,"d":"1.00"},"up","no"]
[126894,0,"chr21","-",34516484,34615142,"ENST00000313806",4,2490,"MSTRG.10009","RCAN1","GO:0003676(nucleic acid binding);GO:0050790(regulation of catalytic activity);GO:0006355(regulation of transcription, DNA-templated);GO:0019722(calcium-mediated signaling);GO:0005737(cytoplasm);GO:0033173(calcineurin-NFAT signaling cascade);GO:0003677(DNA binding);GO:0005634(nucleus);GO:0007165(signal transduction);GO:0007417(central nervous system development);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0008015(blood circulation);GO:0008597(calcium-dependent protein serine/threonine phosphatase regulator activity);GO:0070884(regulation of calcineurin-NFAT signaling cascade);GO:0005622(intracellular);GO:0007519(skeletal muscle tissue development);GO:0009612(response to mechanical stimulus);GO:0043627(response to estrogen);GO:0051151(negative regulation of smooth muscle cell differentiation)","04921(Oxytocin signaling pathway);04919(Thyroid hormone signaling pathway);05167(Kaposi's sarcoma-associated herpesvirus infection)","K17901","NA","regulator of calcineurin 1 [Source:HGNC Symbol;Acc:HGNC:3040]",{"v":2.613602,"d":"2.61"},{"v":2.302136,"d":"2.30"},{"v":1.13529435272286,"d":"1.14"},{"v":0.183066399857075,"d":"0.18"},{"v":0.985270883865102,"d":"0.99"},{"v":0.99982257691911,"d":"1.00"},"up","no"]
[93482,0,"chr18","-",74591774,74597824,"ENST00000580048",2,3463,"ENSG00000264247","LINC00909","NA","NA","NA","NA","long intergenic non-protein coding RNA 909 [Source:HGNC Symbol;Acc:HGNC:44331]",{"v":2.077779,"d":"2.08"},{"v":1.798736,"d":"1.80"},{"v":1.15513282660713,"d":"1.16"},{"v":0.208058754039157,"d":"0.21"},{"v":0.993268277414504,"d":"0.99"},1,"up","no"]
[128721,0,"chr22","+",20122607,20127353,"ENST00000448394",4,688,"MSTRG.10150","RANBP1","GO:0005829(cytosol);GO:0046907(intracellular transport);GO:0005737(cytoplasm);GO:0005634(nucleus);GO:0050790(regulation of catalytic activity);GO:0043547(positive regulation of GTPase activity);GO:0007165(signal transduction);GO:0005096(GTPase activator activity);GO:0005813(centrosome);GO:0045296(cadherin binding);GO:0007051(spindle organization);GO:0005515(protein binding);GO:0008536(Ran GTPase binding);GO:0016032(viral process);GO:0006606(protein import into nucleus);GO:0006511(ubiquitin-dependent protein catabolic process);GO:0006405(RNA export from nucleus);GO:0005635(nuclear envelope);GO:0000082(G1/S transition of mitotic cell cycle);GO:0005092(GDP-dissociation inhibitor activity);GO:0046604(positive regulation of mitotic centrosome separation);GO:0005622(intracellular);GO:0010976(positive regulation of neuron projection development);GO:0035690(cellular response to drug);GO:0051592(response to calcium ion);GO:0072750(cellular response to leptomycin B);GO:0032838(cell projection cytoplasm);GO:1904115(axon cytoplasm)","05203(Viral carcinogenesis);05166(HTLV-I infection)","NA","NA","RAN binding protein 1 [Source:HGNC Symbol;Acc:HGNC:9847]",{"v":0.052961,"d":"0.05"},{"v":0.053657,"d":"0.05"},{"v":0.987028719458784,"d":"0.99"},{"v":-0.0188360316667149,"d":"-0.02"},1,1,"down","no"]
[166020,0,"chr6","-",41937006,42048690,"ENST00000511161",2,579,"MSTRG.13035","CCND3","GO:0001934(positive regulation of protein phosphorylation);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005829(cytosol);GO:0051301(cell division);GO:0005886(plasma membrane);GO:0005925(focal adhesion);GO:0005515(protein binding);GO:0007049(cell cycle);GO:0005654(nucleoplasm);GO:0019901(protein kinase binding);GO:0000307(cyclin-dependent protein kinase holoenzyme complex);GO:0045737(positive regulation of cyclin-dependent protein serine/threonine kinase activity);GO:0004693(cyclin-dependent protein serine/threonine kinase activity);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0007165(signal transduction);GO:0042098(T cell proliferation);GO:0042127(regulation of cell proliferation);GO:0046626(regulation of insulin receptor signaling pathway);GO:0051726(regulation of cell cycle)","04310(Wnt signaling pathway);04390(Hippo signaling pathway);04630(Jak-STAT signaling pathway);04151(PI3K-Akt signaling pathway);04110(Cell cycle);04115(p53 signaling pathway);04218(Cellular senescence);04510(Focal adhesion);05200(Pathways in cancer);05203(Viral carcinogenesis);05166(HTLV-I infection);05162(Measles);05165(Human papillomavirus infection)","NA","NA","cyclin D3 [Source:HGNC Symbol;Acc:HGNC:1585]",{"v":0.12483,"d":"0.12"},{"v":0.021663,"d":"0.02"},{"v":5.76235978396344,"d":"5.76"},{"v":2.52665974073647,"d":"2.53"},1,1,"up","no"]
[28773,0,"chr11","+",47268141,47268844,"ENST00000494018",2,510,"ENSG00000025434","NR1H3","GO:0050728(negative regulation of inflammatory response);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0042632(cholesterol homeostasis);GO:0071222(cellular response to lipopolysaccharide);GO:0005634(nucleus);GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0043565(sequence-specific DNA binding);GO:0005515(protein binding);GO:0003707(steroid hormone receptor activity);GO:0030522(intracellular receptor signaling pathway);GO:0043401(steroid hormone mediated signaling pathway);GO:0045893(positive regulation of transcription, DNA-templated);GO:0005654(nucleoplasm);GO:0003713(transcription coactivator activity);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0000790(nuclear chromatin);GO:0006367(transcription initiation from RNA polymerase II promoter);GO:0044212(transcription regulatory region DNA binding);GO:0090575(RNA polymerase II transcription factor complex);GO:0043277(apoptotic cell clearance);GO:0043235(receptor complex);GO:0032270(positive regulation of cellular protein metabolic process);GO:0015485(cholesterol binding);GO:0010745(negative regulation of macrophage derived foam cell differentiation);GO:0010875(positive regulation of cholesterol efflux);GO:0010887(negative regulation of cholesterol storage);GO:0004879(RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding);GO:0010867(positive regulation of triglyceride biosynthetic process);GO:0032570(response to progesterone);GO:0070328(triglyceride homeostasis);GO:0045723(positive regulation of fatty acid biosynthetic process);GO:0051006(positive regulation of lipoprotein lipase activity);GO:0032369(negative regulation of lipid transport);GO:0010870(positive regulation of receptor biosynthetic process);GO:0055088(lipid homeostasis);GO:0043031(negative regulation of macrophage activation);GO:0034145(positive regulation of toll-like receptor 4 signaling pathway);GO:2000188(regulation of cholesterol homeostasis);GO:0060336(negative regulation of interferon-gamma-mediated signaling pathway);GO:2000189(positive regulation of cholesterol homeostasis);GO:0032376(positive regulation of cholesterol transport);GO:0048550(negative regulation of pinocytosis);GO:0032810(sterol response element binding);GO:0042752(regulation of circadian rhythm);GO:0055092(sterol homeostasis);GO:0090188(negative regulation of pancreatic juice secretion);GO:0090341(negative regulation of secretion of lysosomal enzymes);GO:0006366(transcription from RNA polymerase II promoter);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:0001077(transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0044255(cellular lipid metabolic process);GO:0045861(negative regulation of proteolysis);GO:0045892(negative regulation of transcription, DNA-templated)","03320(PPAR signaling pathway);04932(Non-alcoholic fatty liver disease (NAFLD));04931(Insulin resistance);05160(Hepatitis C)","NA","NA","nuclear receptor subfamily 1 group H member 3 [Source:HGNC Symbol;Acc:HGNC:7966]",0,{"v":0.024697,"d":"0.02"},"-inf","-inf",1,1,"down","no"]
[6909,0,"chr1","+",65148203,65232136,"ENST00000327299",5,6836,"ENSG00000162433","AK4","GO:0005524(ATP binding);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0005739(mitochondrion);GO:0006139(nucleobase-containing compound metabolic process);GO:0019205(nucleobase-containing compound kinase activity);GO:0004017(adenylate kinase activity);GO:0046939(nucleotide phosphorylation);GO:0000166(nucleotide binding);GO:0005525(GTP binding);GO:0005759(mitochondrial matrix);GO:0004550(nucleoside diphosphate kinase activity);GO:0016776(phosphotransferase activity, phosphate group as acceptor);GO:0070062(extracellular exosome);GO:0015949(nucleobase-containing small molecule interconversion);GO:0006165(nucleoside diphosphate phosphorylation);GO:0009142(nucleoside triphosphate biosynthetic process);GO:0046034(ATP metabolic process);GO:0046039(GTP metabolic process);GO:0050145(nucleoside phosphate kinase activity);GO:0046940(nucleoside monophosphate phosphorylation);GO:0046899(nucleoside triphosphate adenylate kinase activity);GO:0046033(AMP metabolic process);GO:0001889(liver development);GO:0007420(brain development);GO:0042493(response to drug)","00230(Purine metabolism);00730(Thiamine metabolism)","K00939","EC:2.7.4.3","adenylate kinase 4 [Source:HGNC Symbol;Acc:HGNC:363]",0,{"v":0.103843,"d":"0.10"},"-inf","-inf",1,1,"down","no"]
[33643,0,"chr11","+",82901727,82934659,"ENST00000533655",6,3533,"MSTRG.2766","DDIAS","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0007049(cell cycle);GO:0006915(apoptotic process);GO:0007050(cell cycle arrest)","NA","NA","NA","DNA damage induced apoptosis suppressor [Source:HGNC Symbol;Acc:HGNC:26351]",{"v":0.669317,"d":"0.67"},0,"inf","inf",1,1,"up","no"]
[183166,0,"chr8","+",38788361,38819622,"ENST00000521154",2,560,"MSTRG.14302","TACC1","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0051301(cell division);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0007049(cell cycle);GO:0005815(microtubule organizing center);GO:0030496(midbody);GO:0000226(microtubule cytoskeleton organization);GO:0008283(cell proliferation);GO:0021987(cerebral cortex development);GO:0015630(microtubule cytoskeleton)","NA","NA","NA","transforming acidic coiled-coil containing protein 1 [Source:HGNC Symbol;Acc:HGNC:11522]",{"v":0.368677,"d":"0.37"},{"v":0.049894,"d":"0.05"},{"v":7.38920511484347,"d":"7.39"},{"v":2.88541917647524,"d":"2.89"},1,1,"up","no"]
[71396,0,"chr16","-",28917823,28925177,"ENST00000564473",4,553,"ENSG00000177548","RABEP2","GO:0006810(transport);GO:0005737(cytoplasm);GO:0015031(protein transport);GO:0043231(intracellular membrane-bounded organelle);GO:0005829(cytosol);GO:0006897(endocytosis);GO:0008083(growth factor activity);GO:0043547(positive regulation of GTPase activity);GO:0005096(GTPase activator activity);GO:0005768(endosome);GO:0005769(early endosome)","NA","NA","NA","rabaptin, RAB GTPase binding effector protein 2 [Source:HGNC Symbol;Acc:HGNC:24817]",{"v":0.006361,"d":"0.01"},0,"inf","inf",1,1,"up","no"]
[102427,0,"chr19","+",44025354,44087318,"ENST00000591793",11,3766,"ENSG00000267022","AC067968.1","GO:0003676(nucleic acid binding);GO:0046872(metal ion binding);GO:0006355(regulation of transcription, DNA-templated);GO:0005622(intracellular)","NA","NA","NA","NA",{"v":0.24019,"d":"0.24"},{"v":0.045278,"d":"0.05"},{"v":5.30478378020231,"d":"5.30"},{"v":2.40729394895587,"d":"2.41"},1,1,"up","no"]
[104014,0,"chr19","-",49661595,49662329,"ENST00000602190",2,413,"MSTRG.8327","IRF3","GO:0005737(cytoplasm);GO:0005634(nucleus);GO:0005829(cytosol);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0005515(protein binding);GO:0006974(cellular response to DNA damage stimulus);GO:0006915(apoptotic process);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0002376(immune system process);GO:0045087(innate immune response);GO:0000975(regulatory region DNA binding);GO:0042802(identical protein binding);GO:0051607(defense response to virus);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:0005654(nucleoplasm);GO:0001228(transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding);GO:0043565(sequence-specific DNA binding);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0016032(viral process);GO:0042803(protein homodimerization activity);GO:0035666(TRIF-dependent toll-like receptor signaling pathway);GO:0006366(transcription from RNA polymerase II promoter);GO:0019904(protein domain specific binding);GO:0032728(positive regulation of interferon-beta production);GO:0003712(transcription cofactor activity);GO:0060333(interferon-gamma-mediated signaling pathway);GO:0001077(transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0032481(positive regulation of type I interferon production);GO:0060337(type I interferon signaling pathway);GO:0032480(negative regulation of type I interferon production);GO:0032727(positive regulation of interferon-alpha production);GO:0032479(regulation of type I interferon production);GO:0039530(MDA-5 signaling pathway);GO:0071888(macrophage apoptotic process);GO:0001078(transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0009617(response to bacterium);GO:0031663(lipopolysaccharide-mediated signaling pathway);GO:0032496(response to lipopolysaccharide);GO:0043123(positive regulation of I-kappaB kinase/NF-kappaB signaling);GO:0043330(response to exogenous dsRNA);GO:0045351(type I interferon biosynthetic process);GO:0050715(positive regulation of cytokine secretion);GO:0060340(positive regulation of type I interferon-mediated signaling pathway);GO:0071222(cellular response to lipopolysaccharide);GO:0071359(cellular response to dsRNA);GO:0097300(programmed necrotic cell death)","04620(Toll-like receptor signaling pathway);04621(NOD-like receptor signaling pathway);04622(RIG-I-like receptor signaling pathway);04623(Cytosolic DNA-sensing pathway);05203(Viral carcinogenesis);05133(Pertussis);05162(Measles);05164(Influenza A);05161(Hepatitis B);05160(Hepatitis C);05168(Herpes simplex infection);05167(Kaposi's sarcoma-associated herpesvirus infection);05169(Epstein-Barr virus infection);05165(Human papillomavirus infection)","NA","NA","interferon regulatory factor 3 [Source:HGNC Symbol;Acc:HGNC:6118]",0,{"v":0.093907,"d":"0.09"},"-inf","-inf",1,1,"down","no"]
[60428,0,"chr15","+",30223017,30225564,"ENST00000569415",1,2548,"ENSG00000259993","AC135731.1","NA","NA","NA","NA","NA",0,0,1,0,1,1,"no","no"]
[136689,0,"chr3","-",50326008,50328251,"ENST00000421918",4,790,"MSTRG.10946","TUSC2","GO:0005515(protein binding);GO:0007049(cell cycle);GO:0007267(cell-cell signaling);GO:0008283(cell proliferation);GO:0001779(natural killer cell differentiation);GO:0006909(phagocytosis);GO:0006954(inflammatory response);GO:0032618(interleukin-15 production);GO:0032700(negative regulation of interleukin-17 production);GO:0032733(positive regulation of interleukin-10 production);GO:0048469(cell maturation);GO:0050829(defense response to Gram-negative bacterium);GO:0051881(regulation of mitochondrial membrane potential);GO:0052567(response to defense-related host reactive oxygen species production);GO:0070945(neutrophil mediated killing of gram-negative bacterium);GO:0071609(chemokine (C-C motif) ligand 5 production);GO:2000377(regulation of reactive oxygen species metabolic process);GO:0005739(mitochondrion)","NA","NA","NA","tumor suppressor candidate 2 [Source:HGNC Symbol;Acc:HGNC:17034]",{"v":0.295898,"d":"0.30"},0,"inf","inf",1,1,"up","no"]
[182879,0,"chr8","-",33593532,33597807,"ENST00000522982",2,729,"ENSG00000133878","DUSP26","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016787(hydrolase activity);GO:0005794(Golgi apparatus);GO:0004725(protein tyrosine phosphatase activity);GO:0008138(protein tyrosine/serine/threonine phosphatase activity);GO:0016791(phosphatase activity);GO:0006470(protein dephosphorylation);GO:0016311(dephosphorylation);GO:0035335(peptidyl-tyrosine dephosphorylation);GO:0004721(phosphoprotein phosphatase activity);GO:0005515(protein binding);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0070062(extracellular exosome);GO:0045785(positive regulation of cell adhesion);GO:0070373(negative regulation of ERK1 and ERK2 cascade);GO:0002039(p53 binding);GO:0044387(negative regulation of protein kinase activity by regulation of protein phosphorylation);GO:0004647(phosphoserine phosphatase activity);GO:0001102(RNA polymerase II activating transcription factor binding);GO:1902310(positive regulation of peptidyl-serine dephosphorylation);GO:0005739(mitochondrion)","NA","NA","NA","dual specificity phosphatase 26 [Source:HGNC Symbol;Acc:HGNC:28161]",0,0,1,0,1,1,"no","no"]
[7603,0,"chr1","+",84164382,84238494,"ENST00000610703",10,4240,"MSTRG.669","PRKACB","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0005829(cytosol);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0045171(intercellular bridge);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0000287(magnesium ion binding);GO:0005813(centrosome);GO:0005654(nucleoplasm);GO:0070062(extracellular exosome);GO:0002223(stimulatory C-type lectin receptor signaling pathway);GO:0031625(ubiquitin protein ligase binding);GO:0007165(signal transduction);GO:0007596(blood coagulation);GO:0003091(renal water homeostasis);GO:0034199(activation of protein kinase A activity);GO:0071377(cellular response to glucagon stimulus);GO:0034380(high-density lipoprotein particle assembly);GO:0097546(ciliary base);GO:0004691(cAMP-dependent protein kinase activity);GO:0005952(cAMP-dependent protein kinase complex);GO:0007188(adenylate cyclase-modulating G-protein coupled receptor signaling pathway);GO:0001843(neural tube closure);GO:0051447(negative regulation of meiotic cell cycle);GO:0070613(regulation of protein processing);GO:0097338(response to clozapine);GO:1901621(negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning);GO:0048471(perinuclear region of cytoplasm)","04014(Ras signaling pathway);04010(MAPK signaling pathway);04310(Wnt signaling pathway);04340(Hedgehog signaling pathway);04371(Apelin signaling pathway);04020(Calcium signaling pathway);04024(cAMP signaling pathway);04140(Autophagy - animal);04114(Oocyte meiosis);04530(Tight junction);04540(Gap junction);04611(Platelet activation);04062(Chemokine signaling pathway);04911(Insulin secretion);04910(Insulin signaling pathway);04922(Glucagon signaling pathway);04923(Regulation of lipolysis in adipocyte);04912(GnRH signaling pathway);04913(Ovarian Steroidogenesis);04915(Estrogen signaling pathway);04914(Progesterone-mediated oocyte maturation);04921(Oxytocin signaling pathway);04926(Relaxin signaling pathway);04918(Thyroid hormone synthesis);04919(Thyroid hormone signaling pathway);04916(Melanogenesis);04924(Renin secretion);04925(Aldosterone synthesis and secretion);04927(Cortisol synthesis and secretion);04261(Adrenergic signaling in cardiomyocytes);04270(Vascular smooth muscle contraction);04970(Salivary secretion);04971(Gastric acid secretion);04976(Bile secretion);04962(Vasopressin-regulated water reabsorption);04961(Endocrine and other factor-regulated calcium reabsorption);04724(Glutamatergic synapse);04727(GABAergic synapse);04725(Cholinergic synapse);04728(Dopaminergic synapse);04726(Serotonergic synapse);04720(Long-term potentiation);04723(Retrograde endocannabinoid signaling);04740(Olfactory transduction);04742(Taste transduction);04750(Inflammatory mediator regulation of TRP channels);04211(Longevity regulating pathway - mammal);04213(Longevity regulating pathway - multiple species);04713(Circadian entrainment);05200(Pathways in cancer);05205(Proteoglycans in cancer);05203(Viral carcinogenesis);05012(Parkinson's disease);05020(Prion diseases);05030(Cocaine addiction);05031(Amphetamine addiction);05032(Morphine addiction);05414(Dilated cardiomyopathy (DCM));05110(Vibrio cholerae infection);05166(HTLV-I infection);05169(Epstein-Barr virus infection);05165(Human papillomavirus infection);05146(Amoebiasis);01522(Endocrine resistance)","K04345","EC:2.7.11.11","protein kinase cAMP-activated catalytic subunit beta [Source:HGNC Symbol;Acc:HGNC:9381]",{"v":0.189671,"d":"0.19"},0,"inf","inf",1,1,"up","no"]
[20289,0,"chr10","-",49458788,49502122,"ENST00000623115",15,2932,"ENSG00000225830","ERCC6","GO:0005634(nucleus);GO:0005794(Golgi apparatus);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0005829(cytosol);GO:0016787(hydrolase activity);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0004386(helicase activity);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0006281(DNA repair);GO:0006974(cellular response to DNA damage stimulus);GO:0005654(nucleoplasm);GO:0005730(nucleolus);GO:0061098(positive regulation of protein tyrosine kinase activity);GO:0006366(transcription from RNA polymerase II promoter);GO:0003682(chromatin binding);GO:0008022(protein C-terminus binding);GO:0006284(base-excision repair);GO:0045815(positive regulation of gene expression, epigenetic);GO:0047485(protein N-terminus binding);GO:0006979(response to oxidative stress);GO:0009411(response to UV);GO:0032786(positive regulation of DNA-templated transcription, elongation);GO:0008023(transcription elongation factor complex);GO:0032403(protein complex binding);GO:0008094(DNA-dependent ATPase activity);GO:0006283(transcription-coupled nucleotide-excision repair);GO:0030296(protein tyrosine kinase activator activity);GO:0000303(response to superoxide);GO:0006290(pyrimidine dimer repair);GO:0006362(transcription elongation from RNA polymerase I promoter);GO:0007256(activation of JNKK activity);GO:0007257(activation of JUN kinase activity);GO:0008630(intrinsic apoptotic signaling pathway in response to DNA damage);GO:0009636(response to toxic substance);GO:0010165(response to X-ray);GO:0010224(response to UV-B);GO:0010332(response to gamma radiation);GO:0032784(regulation of DNA-templated transcription, elongation);GO:0035264(multicellular organism growth);GO:0045494(photoreceptor cell maintenance)","03420(Nucleotide excision repair)","NA","NA","ERCC excision repair 6, chromatin remodeling factor [Source:HGNC Symbol;Acc:HGNC:3438]",{"v":0.061659,"d":"0.06"},0,"inf","inf",1,1,"up","no"]
[116107,0,"chr2","+",169694465,169701708,"ENST00000359744",4,1125,"ENSG00000144362","PHOSPHO2","GO:0046872(metal ion binding);GO:0016787(hydrolase activity);GO:0016791(phosphatase activity);GO:0016311(dephosphorylation);GO:0005515(protein binding);GO:0033883(pyridoxal phosphatase activity)","00750(Vitamin B6 metabolism)","K13248","EC:3.1.3.74","phosphatase, orphan 2 [Source:HGNC Symbol;Acc:HGNC:28316]",0,{"v":0.351112,"d":"0.35"},"-inf","-inf",1,1,"down","no"]
[52513,0,"chr14","-",21020533,21023740,"ENST00000553784",7,943,"MSTRG.4161","NDRG2","GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0042995(cell projection);GO:0005515(protein binding);GO:0007275(multicellular organism development);GO:0016055(Wnt signaling pathway);GO:0048471(perinuclear region of cytoplasm);GO:0007399(nervous system development);GO:0030154(cell differentiation);GO:0003674(molecular_function);GO:0030426(growth cone);GO:0070062(extracellular exosome);GO:0007165(signal transduction);GO:0021762(substantia nigra development);GO:0005794(Golgi apparatus);GO:0001818(negative regulation of cytokine production);GO:0010574(regulation of vascular endothelial growth factor production);GO:0048662(negative regulation of smooth muscle cell proliferation);GO:0070373(negative regulation of ERK1 and ERK2 cascade);GO:0090361(regulation of platelet-derived growth factor production);GO:0005634(nucleus);GO:0016020(membrane);GO:0016021(integral component of membrane)","NA","NA","NA","NDRG family member 2 [Source:HGNC Symbol;Acc:HGNC:14460]",0,0,1,0,1,1,"no","no"]
[6112,0,"chr1","+",52573114,52573816,"ENST00000422983",1,703,"ENSG00000236290","EEF1GP7","NA","NA","NA","NA","eukaryotic translation elongation factor 1 gamma pseudogene 7 [Source:HGNC Symbol;Acc:HGNC:44562]",0,0,1,0,1,1,"no","no"]
[106399,0,"chr19","+",57849860,57854108,"ENST00000484707",2,545,"MSTRG.8461","ZNF587","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0005622(intracellular);GO:0005515(protein binding)","NA","NA","NA","zinc finger protein 587 [Source:HGNC Symbol;Acc:HGNC:30955]",{"v":0.190826,"d":"0.19"},{"v":0.31754,"d":"0.32"},{"v":0.600951061283618,"d":"0.60"},{"v":-0.734680585678312,"d":"-0.73"},1,1,"down","no"]
[78065,0,"chr17","+",4710693,4721061,"ENST00000381488",14,1236,"MSTRG.6331","ARRB2","GO:0005737(cytoplasm);GO:0051898(negative regulation of protein kinase B signaling);GO:0007179(transforming growth factor beta receptor signaling pathway);GO:0006810(transport);GO:0005634(nucleus);GO:0016020(membrane);GO:0015031(protein transport);GO:0043231(intracellular membrane-bounded organelle);GO:0016567(protein ubiquitination);GO:0007165(signal transduction);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0031410(cytoplasmic vesicle);GO:0005905(clathrin-coated pit);GO:0005829(cytosol);GO:0006366(transcription from RNA polymerase II promoter);GO:0061024(membrane organization);GO:0016579(protein deubiquitination);GO:0060071(Wnt signaling pathway, planar cell polarity pathway);GO:0032947(protein complex scaffold);GO:0032088(negative regulation of NF-kappaB transcription factor activity);GO:0031625(ubiquitin protein ligase binding);GO:0005102(receptor binding);GO:0019899(enzyme binding);GO:0045953(negative regulation of natural killer cell mediated cytotoxicity);GO:0070374(positive regulation of ERK1 and ERK2 cascade);GO:0001664(G-protein coupled receptor binding);GO:0030168(platelet activation);GO:0043161(proteasome-mediated ubiquitin-dependent protein catabolic process);GO:0060326(cell chemotaxis);GO:0009968(negative regulation of signal transduction);GO:0031397(negative regulation of protein ubiquitination);GO:0031398(positive regulation of protein ubiquitination);GO:0030139(endocytic vesicle);GO:0002031(G-protein coupled receptor internalization);GO:0002092(positive regulation of receptor internalization);GO:0099565(chemical synaptic transmission, postsynaptic);GO:0031701(angiotensin receptor binding);GO:0002032(desensitization of G-protein coupled receptor protein signaling pathway by arrestin);GO:0007212(dopamine receptor signaling pathway);GO:0031623(receptor internalization);GO:0060765(regulation of androgen receptor signaling pathway);GO:0019904(protein domain specific binding);GO:0031691(alpha-1A adrenergic receptor binding);GO:0031692(alpha-1B adrenergic receptor binding);GO:0031702(type 1 angiotensin receptor binding);GO:0031748(D1 dopamine receptor binding);GO:0031762(follicle-stimulating hormone receptor binding);GO:0031826(type 2A serotonin receptor binding);GO:0031859(platelet activating factor receptor binding);GO:0032403(protein complex binding);GO:0043422(protein kinase B binding);GO:0051019(mitogen-activated protein kinase binding);GO:0071889(14-3-3 protein binding);GO:0001932(regulation of protein phosphorylation);GO:0001933(negative regulation of protein phosphorylation);GO:0001934(positive regulation of protein phosphorylation);GO:0006897(endocytosis);GO:0007186(G-protein coupled receptor signaling pathway);GO:0007420(brain development);GO:0007628(adult walking behavior);GO:0008277(regulation of G-protein coupled receptor protein signaling pathway);GO:0010628(positive regulation of gene expression);GO:0032226(positive regulation of synaptic transmission, dopaminergic);GO:0032691(negative regulation of interleukin-1 beta production);GO:0032695(negative regulation of interleukin-12 production);GO:0032715(negative regulation of interleukin-6 production);GO:0032720(negative regulation of tumor necrosis factor production);GO:0033138(positive regulation of peptidyl-serine phosphorylation);GO:0034122(negative regulation of toll-like receptor signaling pathway);GO:0034260(negative regulation of GTPase activity);GO:0034392(negative regulation of smooth muscle cell apoptotic process);GO:0042699(follicle-stimulating hormone signaling pathway);GO:0043154(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process);GO:0050731(positive regulation of peptidyl-tyrosine phosphorylation);GO:0050965(detection of temperature stimulus involved in sensory perception of pain);GO:0051897(positive regulation of protein kinase B signaling);GO:0051928(positive regulation of calcium ion transport);GO:0090201(negative regulation of release of cytochrome c from mitochondria);GO:2000573(positive regulation of DNA biosynthetic process);GO:2000727(positive regulation of cardiac muscle cell differentiation);GO:0005622(intracellular);GO:0014069(postsynaptic density);GO:0016323(basolateral plasma membrane);GO:0043197(dendritic spine);GO:0045211(postsynaptic membrane)","04010(MAPK signaling pathway);04340(Hedgehog signaling pathway);04144(Endocytosis);04062(Chemokine signaling pathway);04926(Relaxin signaling pathway);04728(Dopaminergic synapse);04740(Olfactory transduction);05032(Morphine addiction)","K04439","NA","arrestin beta 2 [Source:HGNC Symbol;Acc:HGNC:712]",{"v":0.207012,"d":"0.21"},{"v":0.252803,"d":"0.25"},{"v":0.81886686471284,"d":"0.82"},{"v":-0.288299184207685,"d":"-0.29"},1,1,"down","no"]
[120276,0,"chr2","+",232697344,232736268,"ENST00000488734",5,796,"ENSG00000204120","GIGYF2","GO:0003723(RNA binding);GO:0016020(membrane);GO:0005829(cytosol);GO:0005515(protein binding);GO:0005783(endoplasmic reticulum);GO:0045296(cadherin binding);GO:0043234(protein complex);GO:0005794(Golgi apparatus);GO:0017148(negative regulation of translation);GO:0005768(endosome);GO:0070064(proline-rich region binding);GO:0016441(posttranscriptional gene silencing);GO:0048009(insulin-like growth factor receptor signaling pathway);GO:0061157(mRNA destabilization);GO:0010494(cytoplasmic stress granule);GO:0043204(perikaryon);GO:1990635(proximal dendrite);GO:0007631(feeding behavior);GO:0008344(adult locomotory behavior);GO:0009791(post-embryonic development);GO:0021522(spinal cord motor neuron differentiation);GO:0031571(mitotic G1 DNA damage checkpoint);GO:0035264(multicellular organism growth);GO:0044267(cellular protein metabolic process);GO:0048873(homeostasis of number of cells within a tissue);GO:0050881(musculoskeletal movement);GO:0050885(neuromuscular process controlling balance);GO:0005737(cytoplasm);GO:0016021(integral component of membrane);GO:0031982(vesicle)","NA","NA","NA","GRB10 interacting GYF protein 2 [Source:HGNC Symbol;Acc:HGNC:11960]",{"v":0.102308,"d":"0.10"},0,"inf","inf",1,1,"up","no"]
[23872,0,"chr10","-",119499828,119536533,"ENST00000392865",5,852,"MSTRG.2009","RGS10","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005096(GTPase activator activity);GO:0005886(plasma membrane);GO:0043547(positive regulation of GTPase activity);GO:0007213(G-protein coupled acetylcholine receptor signaling pathway);GO:0009968(negative regulation of signal transduction);GO:0001965(G-protein alpha-subunit binding);GO:0043025(neuronal cell body);GO:0043197(dendritic spine);GO:0043679(axon terminus)","NA","NA","NA","regulator of G protein signaling 10 [Source:HGNC Symbol;Acc:HGNC:9992]",{"v":0.231341,"d":"0.23"},{"v":4.691007,"d":"4.69"},{"v":0.0493158505199417,"d":"0.05"},{"v":-4.34180477458684,"d":"-4.34"},1,1,"down","no"]
[86268,0,"chr17","-",59618553,59619714,"ENST00000611877",1,1162,"MSTRG.7069","AC091271.1","NA","NA","NA","NA","NA",{"v":0.364805,"d":"0.36"},{"v":0.175042,"d":"0.18"},{"v":2.08409981604415,"d":"2.08"},{"v":1.05942437582341,"d":"1.06"},1,1,"up","no"]
[105202,0,"chr19","+",53536323,53580269,"ENST00000449416",4,3817,"ENSG00000130844","ZNF331","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0005622(intracellular);GO:0008270(zinc ion binding)","NA","NA","NA","zinc finger protein 331 [Source:HGNC Symbol;Acc:HGNC:15489]",0,{"v":0.000992,"d":"0.00"},"-inf","-inf",1,1,"down","no"]
[142957,0,"chr3","+",179586488,179588241,"ENST00000461125",2,457,"MSTRG.11355","ACTL6A","GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0016569(covalent chromatin modification);GO:0000790(nuclear chromatin);GO:0005515(protein binding);GO:0043044(ATP-dependent chromatin remodeling);GO:0006281(DNA repair);GO:0006310(DNA recombination);GO:0006974(cellular response to DNA damage stimulus);GO:0007399(nervous system development);GO:0040008(regulation of growth);GO:0016579(protein deubiquitination);GO:0043234(protein complex);GO:0071564(npBAF complex);GO:1903146(regulation of mitophagy);GO:0007165(signal transduction);GO:0043967(histone H4 acetylation);GO:0003713(transcription coactivator activity);GO:0006338(chromatin remodeling);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0016514(SWI/SNF complex);GO:1903955(positive regulation of protein targeting to mitochondrion);GO:0003682(chromatin binding);GO:0005886(plasma membrane);GO:0031492(nucleosomal DNA binding);GO:0043968(histone H2A acetylation);GO:0035267(NuA4 histone acetyltransferase complex);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:0000980(RNA polymerase II distal enhancer sequence-specific DNA binding);GO:0003407(neural retina development);GO:0021510(spinal cord development);GO:0031011(Ino80 complex);GO:0090544(BAF-type complex)","05225(Hepatocellular carcinoma)","NA","NA","actin like 6A [Source:HGNC Symbol;Acc:HGNC:24124]",{"v":0.050781,"d":"0.05"},{"v":0.034138,"d":"0.03"},{"v":1.48752123733083,"d":"1.49"},{"v":0.572910265915141,"d":"0.57"},1,1,"up","no"]
[4467,0,"chr1","+",38016583,38023801,"ENST00000488453",6,1895,"ENSG00000183520","UTP11","GO:0005615(extracellular space);GO:0043065(positive regulation of apoptotic process);GO:0005737(cytoplasm);GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005515(protein binding);GO:0005730(nucleolus);GO:0006364(rRNA processing);GO:0032040(small-subunit processome);GO:0042274(ribosomal small subunit biogenesis);GO:0005654(nucleoplasm);GO:0007399(nervous system development)","NA","NA","NA","UTP11, small subunit processome component [Source:HGNC Symbol;Acc:HGNC:24329]",{"v":0.081074,"d":"0.08"},{"v":0.117042,"d":"0.12"},{"v":0.692691512448523,"d":"0.69"},{"v":-0.529715098293162,"d":"-0.53"},1,1,"down","no"]
[151263,0,"chr4","-",145137134,145180161,"ENST00000447906",21,3829,"MSTRG.11887","OTUD4","GO:0003723(RNA binding);GO:0016787(hydrolase activity);GO:0005515(protein binding);GO:0008233(peptidase activity);GO:0008234(cysteine-type peptidase activity);GO:0006508(proteolysis);GO:0036459(thiol-dependent ubiquitinyl hydrolase activity);GO:0005575(cellular_component);GO:0004843(thiol-dependent ubiquitin-specific protease activity);GO:0071108(protein K48-linked deubiquitination)","NA","NA","NA","OTU deubiquitinase 4 [Source:HGNC Symbol;Acc:HGNC:24949]",{"v":3.188371,"d":"3.19"},{"v":0.071779,"d":"0.07"},{"v":44.4192730464342,"d":"44.42"},{"v":5.47311387721651,"d":"5.47"},1,1,"up","no"]
[82165,0,"chr17","-",35101362,35119801,"ENST00000592577",9,762,"MSTRG.6694","RAD51D","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0003677(DNA binding);GO:0008094(DNA-dependent ATPase activity);GO:0005694(chromosome);GO:0006281(DNA repair);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0006310(DNA recombination);GO:0006974(cellular response to DNA damage stimulus);GO:0005813(centrosome);GO:0005815(microtubule organizing center);GO:0003690(double-stranded DNA binding);GO:0006312(mitotic recombination);GO:0000781(chromosome, telomeric region);GO:0005654(nucleoplasm);GO:0000784(nuclear chromosome, telomeric region);GO:0000723(telomere maintenance);GO:0000400(four-way junction DNA binding);GO:0000724(double-strand break repair via homologous recombination);GO:0004520(endodeoxyribonuclease activity);GO:0000150(recombinase activity);GO:0003697(single-stranded DNA binding);GO:0000707(meiotic DNA recombinase assembly);GO:0000731(DNA synthesis involved in DNA repair);GO:0000732(strand displacement);GO:0007131(reciprocal meiotic recombination);GO:0010212(response to ionizing radiation);GO:0005657(replication fork);GO:0033063(Rad51B-Rad51C-Rad51D-XRCC2 complex);GO:0042148(strand invasion);GO:0043015(gamma-tubulin binding);GO:0006289(nucleotide-excision repair);GO:0036297(interstrand cross-link repair);GO:0051276(chromosome organization);GO:0051726(regulation of cell cycle)","03440(Homologous recombination)","NA","NA","RAD51 paralog D [Source:HGNC Symbol;Acc:HGNC:9823]",{"v":0.112645,"d":"0.11"},0,"inf","inf",1,1,"up","no"]
[56903,0,"chr14","-",75011269,75012851,"ENST00000624612",1,1583,"MSTRG.4544","AL049780.3","NA","NA","NA","NA","NA",{"v":0.135448,"d":"0.14"},0,"inf","inf",1,1,"up","no"]
[141460,0,"chr3","-",147386046,147406860,"ENST00000383075",5,4331,"ENSG00000174963","ZIC4","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0003677(DNA binding)","NA","NA","NA","Zic family member 4 [Source:HGNC Symbol;Acc:HGNC:20393]",0,0,1,0,1,1,"no","no"]
[115260,0,"chr2","-",151260985,151261778,"ENST00000409092",2,579,"ENSG00000184898","RBM43","GO:0003676(nucleic acid binding);GO:0003723(RNA binding)","NA","NA","NA","RNA binding motif protein 43 [Source:HGNC Symbol;Acc:HGNC:24790]",{"v":0.503985,"d":"0.50"},{"v":0.248263,"d":"0.25"},{"v":2.03004475092946,"d":"2.03"},{"v":1.0215115309732,"d":"1.02"},1,1,"up","no"]
[20330,0,"chr10","-",49857295,49941970,"ENST00000611974",11,1242,"ENSG00000227345","PARG","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0043231(intracellular membrane-bounded organelle);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0016787(hydrolase activity);GO:0005975(carbohydrate metabolic process);GO:0005739(mitochondrion);GO:0005759(mitochondrial matrix);GO:0005515(protein binding);GO:1990966(ATP generation from poly-ADP-D-ribose);GO:0004649(poly(ADP-ribose) glycohydrolase activity)","NA","NA","NA","poly(ADP-ribose) glycohydrolase [Source:HGNC Symbol;Acc:HGNC:8605]",{"v":0.148397,"d":"0.15"},{"v":0.345271,"d":"0.35"},{"v":0.429798621952032,"d":"0.43"},{"v":-1.21826723777582,"d":"-1.22"},1,1,"down","no"]
[85149,0,"chr17","+",48851101,48852858,"ENST00000514006",3,500,"MSTRG.6982","CALCOCO2","GO:0048471(perinuclear region of cytoplasm);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0043231(intracellular membrane-bounded organelle);GO:0005829(cytosol);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0006914(autophagy);GO:0031410(cytoplasmic vesicle);GO:0000421(autophagosome membrane);GO:0042803(protein homodimerization activity);GO:0005634(nucleus);GO:0098792(xenophagy);GO:0034341(response to interferon-gamma);GO:0005776(autophagosome);GO:1901098(positive regulation of autophagosome maturation);GO:0016032(viral process)","04137(Mitophagy - animal)","NA","NA","calcium binding and coiled-coil domain 2 [Source:HGNC Symbol;Acc:HGNC:29912]",{"v":0.180372,"d":"0.18"},0,"inf","inf",1,1,"up","no"]
[179895,0,"chr7","-",148818037,148884321,"ENST00000483012",12,1491,"ENSG00000106462","EZH2","GO:0018024(histone-lysine N-methyltransferase activity);GO:0034968(histone lysine methylation);GO:0005634(nucleus);GO:0008168(methyltransferase activity);GO:0016740(transferase activity);GO:0032259(methylation);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0016569(covalent chromatin modification);GO:0031490(chromatin DNA binding);GO:0000790(nuclear chromatin);GO:0005515(protein binding);GO:0048511(rhythmic process);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0001047(core promoter binding);GO:0005654(nucleoplasm);GO:0071902(positive regulation of protein serine/threonine kinase activity);GO:0043547(positive regulation of GTPase activity);GO:0048387(negative regulation of retinoic acid receptor signaling pathway);GO:0003682(chromatin binding);GO:0035098(ESC/E(Z) complex);GO:0003677(DNA binding);GO:0045892(negative regulation of transcription, DNA-templated);GO:0010718(positive regulation of epithelial to mesenchymal transition);GO:0042752(regulation of circadian rhythm);GO:0045814(negative regulation of gene expression, epigenetic);GO:0042054(histone methyltransferase activity);GO:0006325(chromatin organization);GO:1990841(promoter-specific chromatin binding);GO:0046976(histone methyltransferase activity (H3-K27 specific));GO:0043406(positive regulation of MAP kinase activity);GO:0016571(histone methylation);GO:0016279(protein-lysine N-methyltransferase activity);GO:0070734(histone H3-K27 methylation);GO:0000975(regulatory region DNA binding);GO:0000979(RNA polymerase II core promoter sequence-specific DNA binding);GO:0003723(RNA binding);GO:0043021(ribonucleoprotein complex binding);GO:0043565(sequence-specific DNA binding);GO:0070878(primary miRNA binding);GO:0001932(regulation of protein phosphorylation);GO:0006306(DNA methylation);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0010468(regulation of gene expression);GO:0010629(negative regulation of gene expression);GO:0014013(regulation of gliogenesis);GO:0014834(skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration);GO:0014898(cardiac muscle hypertrophy in response to stress);GO:0021695(cerebellar cortex development);GO:0021766(hippocampus development);GO:0032355(response to estradiol);GO:0034244(negative regulation of transcription elongation from RNA polymerase II promoter);GO:0035984(cellular response to trichostatin A);GO:0036333(hepatocyte homeostasis);GO:0042127(regulation of cell proliferation);GO:0043433(negative regulation of sequence-specific DNA binding transcription factor activity);GO:0045605(negative regulation of epidermal cell differentiation);GO:0050767(regulation of neurogenesis);GO:0051154(negative regulation of striated muscle cell differentiation);GO:0070301(cellular response to hydrogen peroxide);GO:0070314(G1 to G0 transition);GO:0071168(protein localization to chromatin);GO:0097421(liver regeneration);GO:0098532(histone H3-K27 trimethylation);GO:1900006(positive regulation of dendrite development);GO:1904772(response to tetrachloromethane);GO:2000134(negative regulation of G1/S transition of mitotic cell cycle);GO:0005737(cytoplasm);GO:0045120(pronucleus)","00310(Lysine degradation);05206(MicroRNAs in cancer)","NA","NA","enhancer of zeste 2 polycomb repressive complex 2 subunit [Source:HGNC Symbol;Acc:HGNC:3527]",0,{"v":0.087279,"d":"0.09"},"-inf","-inf",1,1,"down","no"]
[78326,0,"chr17","-",5482810,5486811,"ENST00000571968",3,567,"MSTRG.6357","DERL2","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005515(protein binding);GO:0004252(serine-type endopeptidase activity);GO:0044322(endoplasmic reticulum quality control compartment);GO:0006986(response to unfolded protein);GO:0008284(positive regulation of cell proliferation);GO:0030433(ubiquitin-dependent ERAD pathway);GO:0030176(integral component of endoplasmic reticulum membrane);GO:1904380(endoplasmic reticulum mannose trimming);GO:0030307(positive regulation of cell growth);GO:0030968(endoplasmic reticulum unfolded protein response);GO:0030970(retrograde protein transport, ER to cytosol);GO:1904153(negative regulation of retrograde protein transport, ER to cytosol);GO:0005785(signal recognition particle receptor complex);GO:0048500(signal recognition particle);GO:0001967(suckling behavior);GO:0005769(early endosome);GO:0005770(late endosome);GO:0006508(proteolysis)","04141(Protein processing in endoplasmic reticulum)","NA","NA","derlin 2 [Source:HGNC Symbol;Acc:HGNC:17943]",{"v":0.775416,"d":"0.78"},{"v":0.117163,"d":"0.12"},{"v":6.61826685899132,"d":"6.62"},{"v":2.72645346456998,"d":"2.73"},1,1,"up","no"]
[19652,0,"chr10","+",35127457,35212955,"ENST00000374728",6,1933,"ENSG00000095794","CREM","GO:0005634(nucleus);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0005737(cytoplasm);GO:0006351(transcription, DNA-templated);GO:0005515(protein binding);GO:0048511(rhythmic process);GO:0007275(multicellular organism development);GO:0030154(cell differentiation);GO:0007283(spermatogenesis);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0007165(signal transduction);GO:0000977(RNA polymerase II regulatory region sequence-specific DNA binding);GO:0001227(transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding);GO:0008140(cAMP response element binding protein binding);GO:0006006(glucose metabolic process);GO:0006631(fatty acid metabolic process);GO:0006687(glycosphingolipid metabolic process);GO:0042752(regulation of circadian rhythm);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0048384(retinoic acid receptor signaling pathway);GO:0005667(transcription factor complex)","04261(Adrenergic signaling in cardiomyocytes);05166(HTLV-I infection)","K09052","NA","cAMP responsive element modulator [Source:HGNC Symbol;Acc:HGNC:2352]",{"v":0.103681,"d":"0.10"},{"v":0.193641,"d":"0.19"},{"v":0.535428963907437,"d":"0.54"},{"v":-0.90123291153923,"d":"-0.90"},1,1,"down","no"]
[110487,0,"chr2","+",68734952,68775417,"ENST00000485573",3,599,"MSTRG.8782","ARHGAP25","GO:0007165(signal transduction);GO:0043547(positive regulation of GTPase activity);GO:0005096(GTPase activator activity);GO:0005829(cytosol);GO:0051056(regulation of small GTPase mediated signal transduction)","NA","NA","NA","Rho GTPase activating protein 25 [Source:HGNC Symbol;Acc:HGNC:28951]",{"v":0.582896,"d":"0.58"},0,"inf","inf",1,1,"up","no"]
[34360,0,"chr11","+",95151339,95158057,"ENST00000545216",2,594,"MSTRG.2801","AP000787.1","NA","NA","NA","NA","NA",{"v":0.600525,"d":"0.60"},0,"inf","inf",1,1,"up","no"]
[99726,0,"chr19","-",33299934,33302564,"ENST00000498907",1,2631,"MSTRG.8058","CEBPA","GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0005634(nucleus);GO:0043231(intracellular membrane-bounded organelle);GO:0005654(nucleoplasm);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0042803(protein homodimerization activity);GO:0005515(protein binding);GO:0007275(multicellular organism development);GO:0003713(transcription coactivator activity);GO:0005730(nucleolus);GO:0045444(fat cell differentiation);GO:0008285(negative regulation of cell proliferation);GO:0016032(viral process);GO:0008134(transcription factor binding);GO:0044212(transcription regulatory region DNA binding);GO:0045892(negative regulation of transcription, DNA-templated);GO:0006366(transcription from RNA polymerase II promoter);GO:0090575(RNA polymerase II transcription factor complex);GO:0006091(generation of precursor metabolites and energy);GO:0019221(cytokine-mediated signaling pathway);GO:0001889(liver development);GO:0019900(kinase binding);GO:0042593(glucose homeostasis);GO:0032436(positive regulation of proteasomal ubiquitin-dependent protein catabolic process);GO:0003705(transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding);GO:0045945(positive regulation of transcription from RNA polymerase III promoter);GO:0001228(transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding);GO:0030851(granulocyte differentiation);GO:0030324(lung development);GO:0055088(lipid homeostasis);GO:0030099(myeloid cell differentiation);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:0001077(transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0043565(sequence-specific DNA binding);GO:0000050(urea cycle);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0001892(embryonic placenta development);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0007005(mitochondrion organization);GO:0007219(Notch signaling pathway);GO:0008203(cholesterol metabolic process);GO:0030225(macrophage differentiation);GO:0042127(regulation of cell proliferation);GO:0045600(positive regulation of fat cell differentiation);GO:0045669(positive regulation of osteoblast differentiation);GO:0045736(negative regulation of cyclin-dependent protein serine/threonine kinase activity);GO:0045786(negative regulation of cell cycle);GO:0045893(positive regulation of transcription, DNA-templated);GO:0048469(cell maturation);GO:0048839(inner ear development);GO:0050872(white fat cell differentiation);GO:0050873(brown fat cell differentiation);GO:0071285(cellular response to lithium ion);GO:0071356(cellular response to tumor necrosis factor);GO:0071407(cellular response to organic cyclic compound);GO:0005667(transcription factor complex)","05200(Pathways in cancer);05202(Transcriptional misregulation in cancers);05221(Acute myeloid leukemia);04932(Non-alcoholic fatty liver disease (NAFLD))","K09055","NA","CCAAT/enhancer binding protein alpha [Source:HGNC Symbol;Acc:HGNC:1833]",0,{"v":4.649071,"d":"4.65"},"-inf","-inf",1,1,"down","no"]
[132097,0,"chr22","+",44734108,44737681,"ENST00000475850",2,1965,"ENSG00000186654","PRR5","GO:0007049(cell cycle);GO:0005829(cytosol);GO:0038111(interleukin-7-mediated signaling pathway);GO:0048015(phosphatidylinositol-mediated signaling);GO:0031295(T cell costimulation);GO:0031932(TORC2 complex);GO:0038203(TORC2 signaling);GO:0001934(positive regulation of protein phosphorylation);GO:0014068(positive regulation of phosphatidylinositol 3-kinase signaling)","04150(mTOR signaling pathway)","NA","NA","proline rich 5 [Source:HGNC Symbol;Acc:HGNC:31682]",{"v":0.31577,"d":"0.32"},{"v":0.164965,"d":"0.16"},{"v":1.91416361046283,"d":"1.91"},{"v":0.936714147439128,"d":"0.94"},1,1,"up","no"]
[113054,0,"chr2","-",102719004,102732340,"ENST00000428085",5,576,"ENSG00000135953","MFSD9","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005215(transporter activity);GO:0055085(transmembrane transport)","NA","NA","NA","major facilitator superfamily domain containing 9 [Source:HGNC Symbol;Acc:HGNC:28158]",0,{"v":0.067142,"d":"0.07"},"-inf","-inf",1,1,"down","no"]
[7457,0,"chr1","-",77944055,77948333,"ENST00000489495",3,2156,"MSTRG.660","FUBP1","GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0005634(nucleus);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0010628(positive regulation of gene expression);GO:0006366(transcription from RNA polymerase II promoter);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0003697(single-stranded DNA binding)","NA","NA","NA","far upstream element binding protein 1 [Source:HGNC Symbol;Acc:HGNC:4004]",{"v":0.242221,"d":"0.24"},{"v":0.780519,"d":"0.78"},{"v":0.310333252617809,"d":"0.31"},{"v":-1.68810980305936,"d":"-1.69"},1,1,"down","no"]
[20260,0,"chr10","+",48978345,48982956,"ENST00000490507",3,428,"MSTRG.1706","WDFY4","GO:0016020(membrane);GO:0016021(integral component of membrane)","NA","NA","NA","WDFY family member 4 [Source:HGNC Symbol;Acc:HGNC:29323]",{"v":0.504663,"d":"0.50"},{"v":0.173239,"d":"0.17"},{"v":2.91310270781983,"d":"2.91"},{"v":1.5425565677502,"d":"1.54"},1,1,"up","no"]
[165419,0,"chr6","-",34284887,34426071,"ENST00000639725",9,4782,"MSTRG.12971","RPS10-NUDT3","GO:0016787(hydrolase activity);GO:0005829(cytosol);GO:0000028(ribosomal small subunit assembly);GO:0003723(RNA binding);GO:0003735(structural constituent of ribosome);GO:0022627(cytosolic small ribosomal subunit)","03010(Ribosome)","K02947","NA","RPS10-NUDT3 readthrough [Source:HGNC Symbol;Acc:HGNC:49181]",0,0,1,0,1,1,"no","no"]
[82888,0,"chr17","+",39688101,39695181,"ENST00000584014",4,849,"MSTRG.6790","ERBB2","GO:0001934(positive regulation of protein phosphorylation);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0005829(cytosol);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0004713(protein tyrosine kinase activity);GO:0007169(transmembrane receptor protein tyrosine kinase signaling pathway);GO:0018108(peptidyl-tyrosine phosphorylation);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0007165(signal transduction);GO:0004714(transmembrane receptor protein tyrosine kinase activity);GO:0048471(perinuclear region of cytoplasm);GO:0045727(positive regulation of translation);GO:0004716(signal transducer, downstream of receptor, with protein tyrosine kinase activity);GO:0046854(phosphatidylinositol phosphorylation);GO:0042802(identical protein binding);GO:0000165(MAPK cascade);GO:0090314(positive regulation of protein targeting to membrane);GO:0010008(endosome membrane);GO:0008022(protein C-terminus binding);GO:0046982(protein heterodimerization activity);GO:0043547(positive regulation of GTPase activity);GO:0019903(protein phosphatase binding);GO:0046934(phosphatidylinositol-4,5-bisphosphate 3-kinase activity);GO:0014066(regulation of phosphatidylinositol 3-kinase signaling);GO:0038111(interleukin-7-mediated signaling pathway);GO:0048015(phosphatidylinositol-mediated signaling);GO:0005088(Ras guanyl-nucleotide exchange factor activity);GO:0008283(cell proliferation);GO:0030307(positive regulation of cell growth);GO:0038128(ERBB2 signaling pathway);GO:1901185(negative regulation of ERBB signaling pathway);GO:2000145(regulation of cell motility);GO:0019838(growth factor binding);GO:0043235(receptor complex);GO:0050679(positive regulation of epithelial cell proliferation);GO:0071363(cellular response to growth factor stimulus);GO:0046983(protein dimerization activity);GO:0032886(regulation of microtubule-based process);GO:0071364(cellular response to epidermal growth factor stimulus);GO:0043406(positive regulation of MAP kinase activity);GO:0070372(regulation of ERK1 and ERK2 cascade);GO:0045765(regulation of angiogenesis);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0007166(cell surface receptor signaling pathway);GO:0016323(basolateral plasma membrane);GO:0042060(wound healing);GO:0007167(enzyme linked receptor protein signaling pathway);GO:0001042(RNA polymerase I core binding);GO:0004888(transmembrane signaling receptor activity);GO:0043125(ErbB-3 class receptor binding);GO:0014065(phosphatidylinositol 3-kinase signaling);GO:0045785(positive regulation of cell adhesion);GO:0045943(positive regulation of transcription from RNA polymerase I promoter);GO:0045945(positive regulation of transcription from RNA polymerase III promoter);GO:0046777(protein autophosphorylation);GO:0005622(intracellular);GO:0023014(signal transduction by protein phosphorylation);GO:0035556(intracellular signal transduction);GO:0007399(nervous system development);GO:0007422(peripheral nervous system development);GO:0007507(heart development);GO:0007528(neuromuscular junction development);GO:0008045(motor neuron axon guidance);GO:0010628(positive regulation of gene expression);GO:0033088(negative regulation of immature T cell proliferation in thymus);GO:0042552(myelination);GO:0048709(oligodendrocyte differentiation);GO:0016324(apical plasma membrane);GO:0031410(cytoplasmic vesicle);GO:0043209(myelin sheath)","04012(ErbB signaling pathway);04066(HIF-1 signaling pathway);04020(Calcium signaling pathway);04510(Focal adhesion);04520(Adherens junction);04530(Tight junction);05200(Pathways in cancer);05230(Central carbon metabolism in cancer);05206(MicroRNAs in cancer);05205(Proteoglycans in cancer);05212(Pancreatic cancer);05226(Gastric cancer);05219(Bladder cancer);05215(Prostate cancer);05213(Endometrial cancer);05224(Breast cancer);05223(Non-small cell lung cancer);01521(EGFR tyrosine kinase inhibitor resistance);01524(Platinum drug resistance);01522(Endocrine resistance)","NA","NA","erb-b2 receptor tyrosine kinase 2 [Source:HGNC Symbol;Acc:HGNC:3430]",0,0,1,0,1,1,"no","no"]
[1191,0,"chr1","+",7776383,7776775,"ENST00000602406",1,393,"MSTRG.105","Z98884.2","NA","NA","NA","NA","NA",{"v":0.323824,"d":"0.32"},0,"inf","inf",1,1,"up","no"]
[150430,0,"chr4","-",119391831,119395335,"ENST00000505994",1,3505,"ENSG00000249244","AC110373.1","NA","NA","NA","NA","NA",{"v":0.030311,"d":"0.03"},{"v":0.01452,"d":"0.01"},{"v":2.08753443526171,"d":"2.09"},{"v":1.06179999599222,"d":"1.06"},1,1,"up","no"]
[160320,0,"chr5","+",154190735,154419012,"ENST00000520647",14,4359,"MSTRG.12482","GALNT10","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0046872(metal ion binding);GO:0016740(transferase activity);GO:0030246(carbohydrate binding);GO:0016757(transferase activity, transferring glycosyl groups);GO:0005794(Golgi apparatus);GO:0000139(Golgi membrane);GO:0006486(protein glycosylation);GO:0016266(O-glycan processing);GO:0004653(polypeptide N-acetylgalactosaminyltransferase activity);GO:0006493(protein O-linked glycosylation)","00512(Mucin type O-glycan biosynthesis)","NA","NA","polypeptide N-acetylgalactosaminyltransferase 10 [Source:HGNC Symbol;Acc:HGNC:19873]",0,{"v":2.7e-05,"d":"0.00"},"-inf","-inf",1,1,"down","no"]
[63945,0,"chr15","+",68181211,68190758,"ENST00000563996",4,1168,"MSTRG.5242","PIAS1","GO:0005634(nucleus);GO:0016607(nuclear speck);GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0016874(ligase activity);GO:0005515(protein binding);GO:0003713(transcription coactivator activity);GO:0045893(positive regulation of transcription, DNA-templated);GO:0019789(SUMO transferase activity);GO:0005654(nucleoplasm);GO:0016925(protein sumoylation);GO:0042127(regulation of cell proliferation);GO:0019899(enzyme binding);GO:0003714(transcription corepressor activity);GO:0016605(PML body);GO:0030521(androgen receptor signaling pathway);GO:0007259(JAK-STAT cascade);GO:0060334(regulation of interferon-gamma-mediated signaling pathway);GO:0050681(androgen receptor binding);GO:0032436(positive regulation of proteasomal ubiquitin-dependent protein catabolic process);GO:0061665(SUMO ligase activity);GO:0033235(positive regulation of protein sumoylation);GO:0008022(protein C-terminus binding);GO:0008134(transcription factor binding);GO:0019904(protein domain specific binding);GO:0031625(ubiquitin protein ligase binding);GO:0000082(G1/S transition of mitotic cell cycle);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0007283(spermatogenesis);GO:0008542(visual learning);GO:0043066(negative regulation of apoptotic process);GO:0045444(fat cell differentiation);GO:0051152(positive regulation of smooth muscle cell differentiation);GO:0065004(protein-DNA complex assembly)","04120(Ubiquitin mediated proteolysis);04630(Jak-STAT signaling pathway);05160(Hepatitis C)","NA","NA","protein inhibitor of activated STAT 1 [Source:HGNC Symbol;Acc:HGNC:2752]",{"v":0.44547,"d":"0.45"},{"v":0.475843,"d":"0.48"},{"v":0.936170123339,"d":"0.94"},{"v":-0.0951573708527078,"d":"-0.10"},1,1,"down","no"]
[123408,0,"chr20","+",35855301,35863248,"ENST00000496305",3,588,"MSTRG.9704","PHF20","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0006366(transcription from RNA polymerase II promoter);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0016569(covalent chromatin modification);GO:0031965(nuclear membrane);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0001228(transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:1901796(regulation of signal transduction by p53 class mediator);GO:0071339(MLL1 complex);GO:0000977(RNA polymerase II regulatory region sequence-specific DNA binding);GO:0043995(histone acetyltransferase activity (H4-K5 specific));GO:0043996(histone acetyltransferase activity (H4-K8 specific));GO:0046972(histone acetyltransferase activity (H4-K16 specific));GO:0043981(histone H4-K5 acetylation);GO:0043982(histone H4-K8 acetylation);GO:0043984(histone H4-K16 acetylation);GO:0000123(histone acetyltransferase complex)","NA","NA","NA","PHD finger protein 20 [Source:HGNC Symbol;Acc:HGNC:16098]",{"v":1.83E-4,"d":"0.00"},{"v":0.000172,"d":"0.00"},{"v":1.06395348837209,"d":"1.06"},{"v":0.0894350835819444,"d":"0.09"},1,1,"up","no"]
[65423,0,"chr15","+",78891552,78894753,"ENST00000560710",4,908,"MSTRG.5338","MORF4L1","GO:0005634(nucleus);GO:0016607(nuclear speck);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0016569(covalent chromatin modification);GO:0006325(chromatin organization);GO:0005515(protein binding);GO:0006281(DNA repair);GO:0006310(DNA recombination);GO:0006974(cellular response to DNA damage stimulus);GO:0005654(nucleoplasm);GO:0040008(regulation of growth);GO:0006338(chromatin remodeling);GO:0047485(protein N-terminus binding);GO:0043967(histone H4 acetylation);GO:0000724(double-strand break repair via homologous recombination);GO:0006342(chromatin silencing);GO:0043968(histone H2A acetylation);GO:0035267(NuA4 histone acetyltransferase complex);GO:0016575(histone deacetylation);GO:0016580(Sin3 complex);GO:0003682(chromatin binding);GO:0008283(cell proliferation)","NA","NA","NA","mortality factor 4 like 1 [Source:HGNC Symbol;Acc:HGNC:16989]",{"v":0.068546,"d":"0.07"},{"v":0.226467,"d":"0.23"},{"v":0.30267544498757,"d":"0.30"},{"v":-1.72415645583556,"d":"-1.72"},1,1,"down","no"]
[68558,0,"chr16","-",2839568,2842638,"ENST00000476276",2,2855,"ENSG00000172460","PRSS30P","NA","NA","NA","NA","protease, serine, 30 pseudogene [Source:HGNC Symbol;Acc:HGNC:28753]",{"v":0.233201,"d":"0.23"},{"v":0.302688,"d":"0.30"},{"v":0.770433581773972,"d":"0.77"},{"v":-0.376257505928637,"d":"-0.38"},1,1,"down","no"]
[49312,0,"chr13","+",27621875,27667410,"ENST00000630983",3,1931,"MSTRG.3928","POLR1D","GO:0005634(nucleus);GO:0046983(protein dimerization activity);GO:0003677(DNA binding);GO:0006351(transcription, DNA-templated);GO:0005515(protein binding);GO:0003899(DNA-directed 5'-3' RNA polymerase activity);GO:0005666(DNA-directed RNA polymerase III complex);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0045815(positive regulation of gene expression, epigenetic);GO:0001056(RNA polymerase III activity);GO:0006383(transcription from RNA polymerase III promoter);GO:0032481(positive regulation of type I interferon production);GO:0001054(RNA polymerase I activity);GO:0006361(transcription initiation from RNA polymerase I promoter);GO:0006362(transcription elongation from RNA polymerase I promoter);GO:0006363(termination of RNA polymerase I transcription);GO:0005736(DNA-directed RNA polymerase I complex)","00230(Purine metabolism);00240(Pyrimidine metabolism);03020(RNA polymerase);04623(Cytosolic DNA-sensing pathway);05169(Epstein-Barr virus infection)","NA","NA","RNA polymerase I subunit D [Source:HGNC Symbol;Acc:HGNC:20422]",{"v":0.034538,"d":"0.03"},{"v":0.078606,"d":"0.08"},{"v":0.439381217718749,"d":"0.44"},{"v":-1.18645489486484,"d":"-1.19"},1,1,"down","no"]
[123011,0,"chr20","-",33660251,33674420,"ENST00000606699",6,1022,"ENSG00000125967","NECAB3","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005794(Golgi apparatus);GO:0046872(metal ion binding);GO:0005509(calcium ion binding);GO:0005789(endoplasmic reticulum membrane);GO:0005515(protein binding);GO:0009306(protein secretion);GO:0000137(Golgi cis cisterna);GO:0019538(protein metabolic process);GO:0042984(regulation of amyloid precursor protein biosynthetic process);GO:0005783(endoplasmic reticulum)","NA","NA","NA","N-terminal EF-hand calcium binding protein 3 [Source:HGNC Symbol;Acc:HGNC:15851]",{"v":0.074912,"d":"0.07"},0,"inf","inf",1,1,"up","no"]
[199274,0,"chrX","-",108084775,108091542,"ENST00000372295",6,779,"MSTRG.15398","PSMD10","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0045111(intermediate filament cytoskeleton);GO:0005515(protein binding);GO:0000502(proteasome complex);GO:0006915(apoptotic process);GO:0038095(Fc-epsilon receptor signaling pathway);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0005654(nucleoplasm);GO:0000165(MAPK cascade);GO:0000209(protein polyubiquitination);GO:0002223(stimulatory C-type lectin receptor signaling pathway);GO:0002479(antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent);GO:0006521(regulation of cellular amino acid metabolic process);GO:0010972(negative regulation of G2/M transition of mitotic cell cycle);GO:0016579(protein deubiquitination);GO:0031145(anaphase-promoting complex-dependent catabolic process);GO:0031146(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process);GO:0033209(tumor necrosis factor-mediated signaling pathway);GO:0038061(NIK/NF-kappaB signaling);GO:0043161(proteasome-mediated ubiquitin-dependent protein catabolic process);GO:0043488(regulation of mRNA stability);GO:0043687(post-translational protein modification);GO:0050852(T cell receptor signaling pathway);GO:0051437(positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition);GO:0055085(transmembrane transport);GO:0060071(Wnt signaling pathway, planar cell polarity pathway);GO:0061418(regulation of transcription from RNA polymerase II promoter in response to hypoxia);GO:0090090(negative regulation of canonical Wnt signaling pathway);GO:0090263(positive regulation of canonical Wnt signaling pathway);GO:1902036(regulation of hematopoietic stem cell differentiation);GO:0032088(negative regulation of NF-kappaB transcription factor activity);GO:0031398(positive regulation of protein ubiquitination);GO:0043066(negative regulation of apoptotic process);GO:0008134(transcription factor binding);GO:0051436(negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle);GO:0005838(proteasome regulatory particle);GO:0008540(proteasome regulatory particle, base subcomplex);GO:0070682(proteasome regulatory particle assembly);GO:0030307(positive regulation of cell growth);GO:0090201(negative regulation of release of cytochrome c from mitochondria);GO:0007253(cytoplasmic sequestering of NF-kappaB);GO:0032436(positive regulation of proteasomal ubiquitin-dependent protein catabolic process);GO:0043409(negative regulation of MAPK cascade);GO:0043518(negative regulation of DNA damage response, signal transduction by p53 class mediator);GO:0045737(positive regulation of cyclin-dependent protein serine/threonine kinase activity)","NA","NA","NA","proteasome 26S subunit, non-ATPase 10 [Source:HGNC Symbol;Acc:HGNC:9555]",0,{"v":0.068442,"d":"0.07"},"-inf","-inf",1,1,"down","no"]
[58444,0,"chr14","+",100128621,100141767,"ENST00000554031",9,819,"MSTRG.4664","EVL","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0003779(actin binding);GO:0017124(SH3 domain binding);GO:0008154(actin polymerization or depolymerization);GO:0051289(protein homotetramerization);GO:0005856(cytoskeleton);GO:0042995(cell projection);GO:0005515(protein binding);GO:0007399(nervous system development);GO:0045010(actin nucleation);GO:0005925(focal adhesion);GO:0005829(cytosol);GO:0030027(lamellipodium);GO:0007411(axon guidance);GO:0051496(positive regulation of stress fiber assembly);GO:0009887(animal organ morphogenesis);GO:0007166(cell surface receptor signaling pathway);GO:0007015(actin filament organization);GO:0010633(negative regulation of epithelial cell migration);GO:1900028(negative regulation of ruffle assembly);GO:0005522(profilin binding);GO:0030838(positive regulation of actin filament polymerization)","NA","NA","NA","Enah/Vasp-like [Source:HGNC Symbol;Acc:HGNC:20234]",{"v":0.649679,"d":"0.65"},{"v":0.305217,"d":"0.31"},{"v":2.12858064917747,"d":"2.13"},{"v":1.08989175301093,"d":"1.09"},1,1,"up","no"]
[186206,0,"chr8","-",102254198,102272931,"ENST00000518205",12,1931,"ENSG00000104517","UBR5","GO:0003723(RNA binding);GO:0008270(zinc ion binding);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0016740(transferase activity);GO:0016567(protein ubiquitination);GO:0004842(ubiquitin-protein transferase activity);GO:0043130(ubiquitin binding);GO:0005634(nucleus);GO:0090263(positive regulation of canonical Wnt signaling pathway);GO:0016020(membrane);GO:0046872(metal ion binding);GO:0005515(protein binding);GO:0006281(DNA repair);GO:0006974(cellular response to DNA damage stimulus);GO:0043234(protein complex);GO:0008283(cell proliferation);GO:0006511(ubiquitin-dependent protein catabolic process);GO:0000209(protein polyubiquitination);GO:0034450(ubiquitin-ubiquitin ligase activity);GO:0010628(positive regulation of gene expression);GO:0033160(positive regulation of protein import into nucleus, translocation);GO:0035413(positive regulation of catenin import into nucleus);GO:0050847(progesterone receptor signaling pathway);GO:1901315(negative regulation of histone H2A K63-linked ubiquitination);GO:2000780(negative regulation of double-strand break repair);GO:0048471(perinuclear region of cytoplasm)","04120(Ubiquitin mediated proteolysis)","NA","NA","ubiquitin protein ligase E3 component n-recognin 5 [Source:HGNC Symbol;Acc:HGNC:16806]",{"v":6e-05,"d":"0.00"},0,"inf","inf",1,1,"up","no"]
[137956,0,"chr3","-",69195249,69200898,"ENST00000462512",5,561,"ENSG00000114541","FRMD4B","GO:0005737(cytoplasm);GO:0005856(cytoskeleton);GO:0005615(extracellular space);GO:0090162(establishment of epithelial cell polarity);GO:0001726(ruffle)","NA","NA","NA","FERM domain containing 4B [Source:HGNC Symbol;Acc:HGNC:24886]",{"v":6.7e-05,"d":"0.00"},0,"inf","inf",1,1,"up","no"]
[156920,0,"chr5","+",96702803,96736187,"ENST00000508117",8,571,"MSTRG.12236","CAST","GO:0003723(RNA binding);GO:0005783(endoplasmic reticulum);GO:0005829(cytosol);GO:0005515(protein binding);GO:0004869(cysteine-type endopeptidase inhibitor activity);GO:0030414(peptidase inhibitor activity);GO:0010466(negative regulation of peptidase activity);GO:0045296(cadherin binding);GO:0004866(endopeptidase inhibitor activity);GO:0016020(membrane);GO:2000675(negative regulation of type B pancreatic cell apoptotic process);GO:0010859(calcium-dependent cysteine-type endopeptidase inhibitor activity);GO:0097340(inhibition of cysteine-type endopeptidase activity)","NA","NA","NA","calpastatin [Source:HGNC Symbol;Acc:HGNC:1515]",{"v":0.182494,"d":"0.18"},{"v":4.15E-4,"d":"0.00"},{"v":439.744578313253,"d":"439.74"},{"v":8.78052198034564,"d":"8.78"},1,1,"up","no"]
[29375,0,"chr11","-",57704749,57712221,"ENST00000534677",2,740,"ENSG00000156603","MED19","GO:0005634(nucleus);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0001104(RNA polymerase II transcription cofactor activity);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0016592(mediator complex);GO:0005515(protein binding);GO:0016604(nuclear body);GO:0008134(transcription factor binding);GO:0045944(positive regulation of transcription from RNA polymerase II promoter)","NA","NA","NA","mediator complex subunit 19 [Source:HGNC Symbol;Acc:HGNC:29600]",{"v":0.071156,"d":"0.07"},{"v":0.083693,"d":"0.08"},{"v":0.850202525898223,"d":"0.85"},{"v":-0.234121549747693,"d":"-0.23"},1,1,"down","no"]
[63051,0,"chr15","+",58889967,58894082,"ENST00000452467",2,383,"MSTRG.5140","AC025918.1","NA","NA","NA","NA","NA",{"v":0.20882,"d":"0.21"},{"v":0.01232,"d":"0.01"},{"v":16.9496753246753,"d":"16.95"},{"v":4.08318573332467,"d":"4.08"},1,1,"up","no"]
[113992,0,"chr2","+",120212935,120213275,"ENST00000450967",1,341,"ENSG00000233286","MTND3P10","NA","NA","NA","NA","mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 3 pseudogene 10 [Source:HGNC Symbol;Acc:HGNC:42150]",0,0,1,0,1,1,"no","no"]
[65260,0,"chr15","+",78149378,78169674,"ENST00000559889",11,2461,"ENSG00000166411","IDH3A","GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0000287(magnesium ion binding);GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0006099(tricarboxylic acid cycle);GO:0005739(mitochondrion);GO:0016616(oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor);GO:0051287(NAD binding);GO:0004449(isocitrate dehydrogenase (NAD+) activity);GO:0005759(mitochondrial matrix);GO:0005975(carbohydrate metabolic process);GO:0043209(myelin sheath)","00020(Citrate cycle (TCA cycle))","NA","NA","isocitrate dehydrogenase 3 (NAD(+)) alpha [Source:HGNC Symbol;Acc:HGNC:5384]",0,0,1,0,1,1,"no","no"]
[55923,0,"chr14","-",64939508,64942746,"ENST00000557323",3,778,"MSTRG.4480","GPX2","GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0098869(cellular oxidant detoxification);GO:0004601(peroxidase activity);GO:0004602(glutathione peroxidase activity);GO:0006979(response to oxidative stress);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0009055(electron carrier activity);GO:0034599(cellular response to oxidative stress)","00590(Arachidonic acid metabolism);00480(Glutathione metabolism);04918(Thyroid hormone synthesis)","NA","NA","glutathione peroxidase 2 [Source:HGNC Symbol;Acc:HGNC:4554]",{"v":0.083574,"d":"0.08"},0,"inf","inf",1,1,"up","no"]
[166996,0,"chr6","+",63576881,63580174,"ENST00000627002",4,447,"MSTRG.13098","PTP4A1","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0016787(hydrolase activity);GO:0008138(protein tyrosine/serine/threonine phosphatase activity);GO:0016791(phosphatase activity);GO:0016311(dephosphorylation);GO:0035335(peptidyl-tyrosine dephosphorylation);GO:0005783(endoplasmic reticulum);GO:0005886(plasma membrane);GO:0004721(phosphoprotein phosphatase activity);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0007049(cell cycle);GO:0007275(multicellular organism development);GO:0006470(protein dephosphorylation);GO:0004725(protein tyrosine phosphatase activity);GO:0030335(positive regulation of cell migration);GO:0005634(nucleus);GO:0005819(spindle);GO:0005768(endosome);GO:0070062(extracellular exosome);GO:0005769(early endosome);GO:0009898(cytoplasmic side of plasma membrane)","NA","NA","NA","protein tyrosine phosphatase type IVA, member 1 [Source:HGNC Symbol;Acc:HGNC:9634]",0,0,1,0,1,1,"no","no"]
[90911,0,"chr18","+",12703026,12725658,"ENST00000586587",5,711,"MSTRG.7434","PSMG2","GO:0005634(nucleus);GO:0005515(protein binding);GO:0005829(cytosol);GO:0043248(proteasome assembly);GO:0000502(proteasome complex);GO:0007094(mitotic spindle assembly checkpoint);GO:0043066(negative regulation of apoptotic process);GO:0051726(regulation of cell cycle)","NA","NA","NA","proteasome assembly chaperone 2 [Source:HGNC Symbol;Acc:HGNC:24929]",0,0,1,0,1,1,"no","no"]
[110212,0,"chr2","+",63588982,63599288,"ENST00000436321",6,680,"MSTRG.8737","MDH1","GO:0005737(cytoplasm);GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0006099(tricarboxylic acid cycle);GO:0003824(catalytic activity);GO:0005975(carbohydrate metabolic process);GO:0016616(oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor);GO:0005515(protein binding);GO:0005615(extracellular space);GO:0016615(malate dehydrogenase activity);GO:0030060(L-malate dehydrogenase activity);GO:0006108(malate metabolic process);GO:0019752(carboxylic acid metabolic process);GO:0005739(mitochondrion);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0006094(gluconeogenesis);GO:0004470(malic enzyme activity);GO:0047860(diiodophenylpyruvate reductase activity);GO:0006107(oxaloacetate metabolic process);GO:0006734(NADH metabolic process);GO:0051287(NAD binding);GO:0019674(NAD metabolic process);GO:0043209(myelin sheath)","00020(Citrate cycle (TCA cycle));00620(Pyruvate metabolism);00630(Glyoxylate and dicarboxylate metabolism);00270(Cysteine and methionine metabolism);04964(Proximal tubule bicarbonate reclamation)","NA","NA","malate dehydrogenase 1 [Source:HGNC Symbol;Acc:HGNC:6970]",0,0,1,0,1,1,"no","no"]
[168005,0,"chr6","-",99919910,99994223,"ENST00000281806",6,2368,"ENSG00000152034","MCHR2","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0004930(G-protein coupled receptor activity);GO:0007186(G-protein coupled receptor signaling pathway);GO:0005886(plasma membrane);GO:0004871(signal transducer activity);GO:0007165(signal transduction);GO:0005887(integral component of plasma membrane);GO:0007200(phospholipase C-activating G-protein coupled receptor signaling pathway);GO:0007218(neuropeptide signaling pathway);GO:0008528(G-protein coupled peptide receptor activity)","04080(Neuroactive ligand-receptor interaction)","K05054","NA","melanin concentrating hormone receptor 2 [Source:HGNC Symbol;Acc:HGNC:20867]",0,0,1,0,1,1,"no","no"]
[152406,0,"chr4","-",175633447,176002664,"ENST00000506894",7,2614,"ENSG00000150625","GPM6A","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005886(plasma membrane);GO:0042995(cell projection);GO:0005515(protein binding);GO:0007399(nervous system development);GO:0070588(calcium ion transmembrane transport);GO:0030424(axon);GO:0048812(neuron projection morphogenesis);GO:0030175(filopodium);GO:0044295(axonal growth cone);GO:0070062(extracellular exosome);GO:0048863(stem cell differentiation);GO:0043197(dendritic spine);GO:0043005(neuron projection);GO:0051491(positive regulation of filopodium assembly);GO:1903561(extracellular vesicle);GO:0001764(neuron migration);GO:0043025(neuronal cell body);GO:0007416(synapse assembly);GO:0005262(calcium channel activity);GO:0003407(neural retina development)","NA","NA","NA","glycoprotein M6A [Source:HGNC Symbol;Acc:HGNC:4460]",0,0,1,0,1,1,"no","no"]
[67405,0,"chr16","+",401883,410306,"ENST00000633923",5,509,"MSTRG.5484","DECR2","GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0006629(lipid metabolic process);GO:0006631(fatty acid metabolic process);GO:0006636(unsaturated fatty acid biosynthetic process);GO:0005777(peroxisome);GO:0005102(receptor binding);GO:0005778(peroxisomal membrane);GO:0033540(fatty acid beta-oxidation using acyl-CoA oxidase);GO:0008670(2,4-dienoyl-CoA reductase (NADPH) activity);GO:0019166(trans-2-enoyl-CoA reductase (NADPH) activity)","04146(Peroxisome)","NA","NA","2,4-dienoyl-CoA reductase 2 [Source:HGNC Symbol;Acc:HGNC:2754]",{"v":0.199972,"d":"0.20"},{"v":8.6e-05,"d":"0.00"},{"v":2325.25581395349,"d":"2325.26"},{"v":11.1831737282893,"d":"11.18"},1,1,"up","no"]
[170814,0,"chr6","+",166388136,166389920,"ENST00000623222",1,1785,"ENSG00000280057","AL022069.2","NA","NA","NA","NA","NA",0,0,1,0,1,1,"no","no"]
[36539,0,"chr11","+",124876875,124879944,"ENST00000531075",6,662,"ENSG00000154134","ROBO3","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0007411(axon guidance);GO:0007275(multicellular organism development);GO:0007399(nervous system development);GO:0030154(cell differentiation);GO:0006935(chemotaxis);GO:0035385(Roundabout signaling pathway);GO:0030424(axon);GO:0016199(axon midline choice point recognition)","04360(Axon guidance)","NA","NA","roundabout guidance receptor 3 [Source:HGNC Symbol;Acc:HGNC:13433]",0,{"v":0.017498,"d":"0.02"},"-inf","-inf",1,1,"down","no"]
[187726,0,"chr8","+",141340549,141344621,"ENST00000521073",4,796,"ENSG00000253595","LINC01300","NA","NA","NA","NA","long intergenic non-protein coding RNA 1300 [Source:HGNC Symbol;Acc:HGNC:50460]",{"v":0.064745,"d":"0.06"},0,"inf","inf",1,1,"up","no"]
[197524,0,"chrX","-",53411995,53422669,"ENST00000463684",4,880,"MSTRG.15309","SMC1A","GO:0003723(RNA binding);GO:0005634(nucleus);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0051301(cell division);GO:0005694(chromosome);GO:0006281(DNA repair);GO:0005515(protein binding);GO:0051276(chromosome organization);GO:0006974(cellular response to DNA damage stimulus);GO:0007049(cell cycle);GO:0051321(meiotic cell cycle);GO:0003682(chromatin binding);GO:0000775(chromosome, centromeric region);GO:0000776(kinetochore);GO:0000777(condensed chromosome kinetochore);GO:0007064(mitotic sister chromatid cohesion);GO:0008278(cohesin complex);GO:0007052(mitotic spindle organization);GO:0007062(sister chromatid cohesion);GO:0016363(nuclear matrix);GO:0046982(protein heterodimerization activity);GO:0097431(mitotic spindle pole);GO:0000794(condensed nuclear chromosome);GO:0009314(response to radiation);GO:0000070(mitotic sister chromatid segregation);GO:0032876(negative regulation of DNA endoreduplication);GO:0032403(protein complex binding);GO:0036033(mediator complex binding);GO:0019827(stem cell population maintenance);GO:0072423(response to DNA damage checkpoint signaling);GO:0030893(meiotic cohesin complex)","04110(Cell cycle);04114(Oocyte meiosis)","NA","NA","structural maintenance of chromosomes 1A [Source:HGNC Symbol;Acc:HGNC:11111]",0,0,1,0,1,1,"no","no"]
[16140,0,"chr1","+",220137642,220140218,"ENST00000488777",3,570,"MSTRG.1394","IARS2","GO:0005737(cytoplasm);GO:0006412(translation);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0005829(cytosol);GO:0005739(mitochondrion);GO:0016874(ligase activity);GO:0005759(mitochondrial matrix);GO:0004812(aminoacyl-tRNA ligase activity);GO:0006418(tRNA aminoacylation for protein translation);GO:0002161(aminoacyl-tRNA editing activity);GO:0006450(regulation of translational fidelity);GO:0000049(tRNA binding);GO:0004822(isoleucine-tRNA ligase activity);GO:0006428(isoleucyl-tRNA aminoacylation)","00970(Aminoacyl-tRNA biosynthesis)","NA","NA","isoleucyl-tRNA synthetase 2, mitochondrial [Source:HGNC Symbol;Acc:HGNC:29685]",{"v":0.213076,"d":"0.21"},{"v":0.005913,"d":"0.01"},{"v":36.0351767292407,"d":"36.04"},{"v":5.17133401573695,"d":"5.17"},1,1,"up","no"]
[6008,0,"chr1","+",51729904,51788469,"ENST00000462759",20,2755,"MSTRG.557","OSBPL9","GO:0006810(transport);GO:0016020(membrane);GO:0005794(Golgi apparatus);GO:0043231(intracellular membrane-bounded organelle);GO:0005829(cytosol);GO:0006869(lipid transport);GO:0008289(lipid binding);GO:0005768(endosome);GO:0031902(late endosome membrane);GO:0006699(bile acid biosynthetic process);GO:0015248(sterol transporter activity);GO:0015918(sterol transport)","NA","NA","NA","oxysterol binding protein like 9 [Source:HGNC Symbol;Acc:HGNC:16386]",{"v":0.251549,"d":"0.25"},{"v":1.953924,"d":"1.95"},{"v":0.128740421838311,"d":"0.13"},{"v":-2.95746299370136,"d":"-2.96"},1,1,"down","no"]
[84104,0,"chr17","-",44191805,44196053,"ENST00000591295",7,3017,"MSTRG.6892","ATXN7L3","GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0016569(covalent chromatin modification);GO:0003713(transcription coactivator activity);GO:0030374(ligand-dependent nuclear receptor transcription coactivator activity);GO:0016578(histone deubiquitination);GO:0045893(positive regulation of transcription, DNA-templated);GO:0000124(SAGA complex);GO:0005515(protein binding)","NA","NA","NA","ataxin 7 like 3 [Source:HGNC Symbol;Acc:HGNC:25416]",{"v":0.000153,"d":"0.00"},{"v":0.100786,"d":"0.10"},{"v":1.51806798563293E-3,"d":"0.00"},{"v":-9.36354788235458,"d":"-9.36"},1,1,"down","no"]
[88515,0,"chr17","+",76726830,76733516,"ENST00000589977",4,617,"MSTRG.7259","METTL23","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0008168(methyltransferase activity);GO:0016740(transferase activity);GO:0032259(methylation);GO:0005515(protein binding);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0043234(protein complex);GO:0008134(transcription factor binding);GO:0050890(cognition);GO:0031072(heat shock protein binding)","NA","NA","NA","methyltransferase like 23 [Source:HGNC Symbol;Acc:HGNC:26988]",{"v":0.223883,"d":"0.22"},{"v":0.152261,"d":"0.15"},{"v":1.47038965986037,"d":"1.47"},{"v":0.556198526390961,"d":"0.56"},1,1,"up","no"]
[101610,0,"chr19","+",40613414,40619376,"ENST00000612845",5,527,"ENSG00000090006","LTBP4","GO:0005509(calcium ion binding);GO:0005615(extracellular space);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0007275(multicellular organism development);GO:0005578(proteinaceous extracellular matrix);GO:0070062(extracellular exosome);GO:0031012(extracellular matrix);GO:0030162(regulation of proteolysis);GO:0006457(protein folding);GO:0001558(regulation of cell growth);GO:0005178(integrin binding);GO:0019838(growth factor binding);GO:0045595(regulation of cell differentiation);GO:0005539(glycosaminoglycan binding);GO:0017015(regulation of transforming growth factor beta receptor signaling pathway);GO:0050431(transforming growth factor beta binding);GO:0030252(growth hormone secretion);GO:0005024(transforming growth factor beta-activated receptor activity);GO:0007179(transforming growth factor beta receptor signaling pathway);GO:0046879(hormone secretion)","NA","NA","NA","latent transforming growth factor beta binding protein 4 [Source:HGNC Symbol;Acc:HGNC:6717]",{"v":0.051538,"d":"0.05"},0,"inf","inf",1,1,"up","no"]
[32604,0,"chr11","+",71998929,72005715,"ENST00000343898",7,1720,"MSTRG.2663","IL18BP","GO:0005576(extracellular region);GO:0005615(extracellular space);GO:0070062(extracellular exosome);GO:0042088(T-helper 1 type immune response);GO:1900116(extracellular negative regulation of signal transduction);GO:0042007(interleukin-18 binding);GO:0048019(receptor antagonist activity);GO:0032496(response to lipopolysaccharide);GO:0070301(cellular response to hydrogen peroxide);GO:0071356(cellular response to tumor necrosis factor)","NA","NA","NA","interleukin 18 binding protein [Source:HGNC Symbol;Acc:HGNC:5987]",{"v":0.661972,"d":"0.66"},{"v":0.025495,"d":"0.03"},{"v":25.9647774073348,"d":"25.96"},{"v":4.69848395232883,"d":"4.70"},1,1,"up","no"]
[175031,0,"chr7","+",74210006,74219972,"ENST00000361082",6,581,"MSTRG.13713","LAT2","GO:0042113(B cell activation);GO:0002764(immune response-regulating signaling pathway);GO:0005622(intracellular);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005886(plasma membrane);GO:0002376(immune system process);GO:0002250(adaptive immune response);GO:0038095(Fc-epsilon receptor signaling pathway);GO:0042629(mast cell granule);GO:0070062(extracellular exosome);GO:0005515(protein binding);GO:0043303(mast cell degranulation);GO:0019722(calcium-mediated signaling);GO:0035556(intracellular signal transduction);GO:0045121(membrane raft);GO:0042169(SH2 domain binding);GO:0050853(B cell receptor signaling pathway)","NA","NA","NA","linker for activation of T-cells family member 2 [Source:HGNC Symbol;Acc:HGNC:12749]",{"v":0.159101,"d":"0.16"},{"v":0.642193,"d":"0.64"},{"v":0.24774639399682,"d":"0.25"},{"v":-2.01306403606597,"d":"-2.01"},1,1,"down","no"]
[85176,0,"chr17","+",48910690,48927054,"ENST00000504684",5,598,"MSTRG.6991","UBE2Z","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0016740(transferase activity);GO:0016567(protein ubiquitination);GO:0005515(protein binding);GO:0006915(apoptotic process);GO:0031625(ubiquitin protein ligase binding);GO:0061630(ubiquitin protein ligase activity);GO:0043065(positive regulation of apoptotic process);GO:0061631(ubiquitin conjugating enzyme activity);GO:0042787(protein ubiquitination involved in ubiquitin-dependent protein catabolic process)","04120(Ubiquitin mediated proteolysis)","NA","NA","ubiquitin conjugating enzyme E2 Z [Source:HGNC Symbol;Acc:HGNC:25847]",{"v":0.073508,"d":"0.07"},{"v":0.523067,"d":"0.52"},{"v":0.14053266598734,"d":"0.14"},{"v":-2.8310225795279,"d":"-2.83"},1,1,"down","no"]
[28571,0,"chr11","+",46617536,46645419,"ENST00000581416",6,741,"MSTRG.2362","ATG13","GO:0005737(cytoplasm);GO:0006914(autophagy);GO:0005829(cytosol);GO:0005515(protein binding);GO:0005789(endoplasmic reticulum membrane);GO:0019901(protein kinase binding);GO:0000045(autophagosome assembly);GO:0000407(pre-autophagosomal structure);GO:1990316(ATG1/ULK1 kinase complex);GO:0005739(mitochondrion);GO:1903955(positive regulation of protein targeting to mitochondrion);GO:0016241(regulation of macroautophagy);GO:0016236(macroautophagy);GO:0000423(macromitophagy);GO:0098780(response to mitochondrial depolarisation)","04140(Autophagy - animal);04136(Autophagy - other eukaryotes);04211(Longevity regulating pathway - mammal)","NA","NA","autophagy related 13 [Source:HGNC Symbol;Acc:HGNC:29091]",{"v":0.188576,"d":"0.19"},{"v":0.069335,"d":"0.07"},{"v":2.71978077450061,"d":"2.72"},{"v":1.44349036901715,"d":"1.44"},1,1,"up","no"]
[177234,0,"chr7","-",102347206,102356444,"ENST00000563237",8,1691,"ENSG00000260097","SPDYE6","NA","04114(Oocyte meiosis);04914(Progesterone-mediated oocyte maturation)","K08694","NA","speedy/RINGO cell cycle regulator family member E6 [Source:HGNC Symbol;Acc:HGNC:35465]",{"v":0.998033,"d":"1.00"},{"v":0.350666,"d":"0.35"},{"v":2.84610712187666,"d":"2.85"},{"v":1.50898996309132,"d":"1.51"},1,1,"up","no"]
[29945,0,"chr11","+",61366979,61369211,"ENST00000539776",2,1635,"MSTRG.2443","TMEM138","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0042995(cell projection);GO:0060271(cilium assembly);GO:0005929(cilium);GO:0030030(cell projection organization);GO:0005773(vacuole);GO:0005774(vacuolar membrane)","NA","NA","NA","transmembrane protein 138 [Source:HGNC Symbol;Acc:HGNC:26944]",{"v":0.002328,"d":"0.00"},{"v":0.054223,"d":"0.05"},{"v":0.0429338103756708,"d":"0.04"},{"v":-4.54174197212203,"d":"-4.54"},1,1,"down","no"]
[44207,0,"chr12","+",68808464,68839867,"ENST00000258148",9,1361,"ENSG00000135679","MDM2","GO:0008284(positive regulation of cell proliferation);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0043066(negative regulation of apoptotic process);GO:0016740(transferase activity);GO:0016567(protein ubiquitination);GO:0008270(zinc ion binding);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0016874(ligase activity);GO:0005515(protein binding);GO:0071157(negative regulation of cell cycle arrest);GO:0005654(nucleoplasm);GO:0016925(protein sumoylation);GO:0005730(nucleolus);GO:0005886(plasma membrane);GO:0042802(identical protein binding);GO:0061630(ubiquitin protein ligase activity);GO:0006977(DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest);GO:0005829(cytosol);GO:0016579(protein deubiquitination);GO:0016032(viral process);GO:0042787(protein ubiquitination involved in ubiquitin-dependent protein catabolic process);GO:0031625(ubiquitin protein ligase binding);GO:0043021(ribonucleoprotein complex binding);GO:0019899(enzyme binding);GO:0004842(ubiquitin-protein transferase activity);GO:0045892(negative regulation of transcription, DNA-templated);GO:0019789(SUMO transferase activity);GO:1901796(regulation of signal transduction by p53 class mediator);GO:0043234(protein complex);GO:0030666(endocytic vesicle membrane);GO:0032436(positive regulation of proteasomal ubiquitin-dependent protein catabolic process);GO:0034504(protein localization to nucleus);GO:0006461(protein complex assembly);GO:0071456(cellular response to hypoxia);GO:0002039(p53 binding);GO:0043518(negative regulation of DNA damage response, signal transduction by p53 class mediator);GO:0046677(response to antibiotic);GO:0051865(protein autoubiquitination);GO:0045931(positive regulation of mitotic cell cycle);GO:0097718(disordered domain specific binding);GO:0042176(regulation of protein catabolic process);GO:0071480(cellular response to gamma radiation);GO:0047485(protein N-terminus binding);GO:0031648(protein destabilization);GO:0016604(nuclear body);GO:0072717(cellular response to actinomycin D);GO:1990000(amyloid fibril formation);GO:0045184(establishment of protein localization);GO:0036369(transcription factor catabolic process);GO:0008097(5S rRNA binding);GO:0042975(peroxisome proliferator activated receptor binding);GO:0061663(NEDD8 ligase activity);GO:0097110(scaffold protein binding);GO:0001568(blood vessel development);GO:0001974(blood vessel remodeling);GO:0002027(regulation of heart rate);GO:0003170(heart valve development);GO:0003181(atrioventricular valve morphogenesis);GO:0003203(endocardial cushion morphogenesis);GO:0003281(ventricular septum development);GO:0003283(atrial septum development);GO:0007089(traversing start control point of mitotic cell cycle);GO:0007507(heart development);GO:0009636(response to toxic substance);GO:0010039(response to iron ion);GO:0010468(regulation of gene expression);GO:0010628(positive regulation of gene expression);GO:0010629(negative regulation of gene expression);GO:0010955(negative regulation of protein processing);GO:0010977(negative regulation of neuron projection development);GO:0018205(peptidyl-lysine modification);GO:0032026(response to magnesium ion);GO:0042220(response to cocaine);GO:0042493(response to drug);GO:0043154(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process);GO:0043278(response to morphine);GO:0045472(response to ether);GO:0045787(positive regulation of cell cycle);GO:0046827(positive regulation of protein export from nucleus);GO:0048545(response to steroid hormone);GO:0051603(proteolysis involved in cellular protein catabolic process);GO:0060411(cardiac septum morphogenesis);GO:0070301(cellular response to hydrogen peroxide);GO:0071236(cellular response to antibiotic);GO:0071301(cellular response to vitamin B1);GO:0071310(cellular response to organic substance);GO:0071312(cellular response to alkaloid);GO:0071363(cellular response to growth factor stimulus);GO:0071375(cellular response to peptide hormone stimulus);GO:0071391(cellular response to estrogen stimulus);GO:0071407(cellular response to organic cyclic compound);GO:0071494(cellular response to UV-C);GO:1901797(negative regulation of signal transduction by p53 class mediator);GO:1902254(negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator);GO:1904404(response to formaldehyde);GO:1904707(positive regulation of vascular smooth muscle cell proliferation);GO:1904754(positive regulation of vascular associated smooth muscle cell migration);GO:1990785(response to water-immersion restraint stress);GO:0045202(synapse)","04120(Ubiquitin mediated proteolysis);04068(FoxO signaling pathway);04151(PI3K-Akt signaling pathway);04144(Endocytosis);04110(Cell cycle);04115(p53 signaling pathway);04218(Cellular senescence);04919(Thyroid hormone signaling pathway);05200(Pathways in cancer);05202(Transcriptional misregulation in cancers);05206(MicroRNAs in cancer);05205(Proteoglycans in cancer);05203(Viral carcinogenesis);05214(Glioma);05220(Chronic myeloid leukemia);05218(Melanoma);05219(Bladder cancer);05215(Prostate cancer);05169(Epstein-Barr virus infection);05165(Human papillomavirus infection);01524(Platinum drug resistance);01522(Endocrine resistance)","K06643","EC:2.3.2.27","MDM2 proto-oncogene [Source:HGNC Symbol;Acc:HGNC:6973]",0,0,1,0,1,1,"no","no"]
[24240,0,"chr10","-",125725634,125749525,"ENST00000630227",2,384,"ENSG00000236991","EDRF1-AS1","NA","NA","NA","NA","EDRF1 antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:49501]",{"v":0.058631,"d":"0.06"},0,"inf","inf",1,1,"up","no"]
[14752,0,"chr1","-",201363329,201373315,"ENST00000466570",9,793,"ENSG00000118194","TNNT2","GO:0003779(actin binding);GO:0005515(protein binding);GO:0005861(troponin complex);GO:0006937(regulation of muscle contraction);GO:0005829(cytosol);GO:0055010(ventricular cardiac muscle tissue morphogenesis);GO:0030049(muscle filament sliding);GO:0032781(positive regulation of ATPase activity);GO:0051592(response to calcium ion);GO:0005523(tropomyosin binding);GO:0030017(sarcomere);GO:0097512(cardiac myofibril);GO:0030172(troponin C binding);GO:0032780(negative regulation of ATPase activity);GO:1990584(cardiac Troponin complex);GO:0008016(regulation of heart contraction);GO:0005865(striated muscle thin filament);GO:0031013(troponin I binding);GO:0060048(cardiac muscle contraction);GO:0030674(protein binding, bridging);GO:0006936(muscle contraction);GO:0032972(regulation of muscle filament sliding speed);GO:0051291(protein heterooligomerization);GO:0051764(actin crosslink formation);GO:0030016(myofibril)","04260(Cardiac muscle contraction);04261(Adrenergic signaling in cardiomyocytes);05410(Hypertrophic cardiomyopathy (HCM));05414(Dilated cardiomyopathy (DCM))","NA","NA","troponin T2, cardiac type [Source:HGNC Symbol;Acc:HGNC:11949]",0,0,1,0,1,1,"no","no"]
[130194,0,"chr22","+",30356635,30376829,"ENST00000405659",12,3052,"MSTRG.10367","CCDC157","NA","NA","NA","NA","coiled-coil domain containing 157 [Source:HGNC Symbol;Acc:HGNC:33854]",{"v":0.02232,"d":"0.02"},{"v":0.094932,"d":"0.09"},{"v":0.235115661736822,"d":"0.24"},{"v":-2.08855745059032,"d":"-2.09"},1,1,"down","no"]
[51421,0,"chr13","-",98455982,98519267,"ENST00000444574",10,1590,"MSTRG.4066","STK24","GO:0005737(cytoplasm);GO:0005634(nucleus);GO:0016020(membrane);GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0005730(nucleolus);GO:0005829(cytosol);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0000165(MAPK cascade);GO:0016310(phosphorylation);GO:0005794(Golgi apparatus);GO:0005515(protein binding);GO:0006915(apoptotic process);GO:0000185(activation of MAPKKK activity);GO:0005654(nucleoplasm);GO:0045296(cadherin binding);GO:0070062(extracellular exosome);GO:0009267(cellular response to starvation);GO:0048812(neuron projection morphogenesis);GO:0007165(signal transduction);GO:0042981(regulation of apoptotic process);GO:0046777(protein autophosphorylation);GO:0097194(execution phase of apoptosis);GO:0008349(MAP kinase kinase kinase kinase activity);GO:0007346(regulation of mitotic cell cycle);GO:0042542(response to hydrogen peroxide);GO:0030336(negative regulation of cell migration);GO:0008631(intrinsic apoptotic signaling pathway in response to oxidative stress);GO:0031098(stress-activated protein kinase signaling cascade);GO:0048679(regulation of axon regeneration)","NA","NA","NA","serine/threonine kinase 24 [Source:HGNC Symbol;Acc:HGNC:11403]",{"v":0.017468,"d":"0.02"},0,"inf","inf",1,1,"up","no"]
[90579,0,"chr18","+",9117387,9119525,"ENST00000474350",3,632,"MSTRG.7401","NDUFV2","GO:0016020(membrane);GO:0046872(metal ion binding);GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0005739(mitochondrion);GO:0005743(mitochondrial inner membrane);GO:0005515(protein binding);GO:0007399(nervous system development);GO:0070469(respiratory chain);GO:0051536(iron-sulfur cluster binding);GO:0051537(2 iron, 2 sulfur cluster binding);GO:0003954(NADH dehydrogenase activity);GO:0008137(NADH dehydrogenase (ubiquinone) activity);GO:0006120(mitochondrial electron transport, NADH to ubiquinone);GO:0032981(mitochondrial respiratory chain complex I assembly);GO:0005747(mitochondrial respiratory chain complex I);GO:0009055(electron carrier activity);GO:0048738(cardiac muscle tissue development);GO:0043209(myelin sheath)","00190(Oxidative phosphorylation);04723(Retrograde endocannabinoid signaling);05010(Alzheimer's disease);05012(Parkinson's disease);05016(Huntington's disease);04932(Non-alcoholic fatty liver disease (NAFLD))","NA","NA","NADH:ubiquinone oxidoreductase core subunit V2 [Source:HGNC Symbol;Acc:HGNC:7717]",{"v":0.20065,"d":"0.20"},{"v":0.077079,"d":"0.08"},{"v":2.60317336758391,"d":"2.60"},{"v":1.3802713963462,"d":"1.38"},1,1,"up","no"]
[137913,0,"chr3","+",69013941,69048888,"ENST00000482368",2,962,"MSTRG.11042","AC109587.1","NA","NA","NA","NA","NA",{"v":0.025585,"d":"0.03"},{"v":0.004905,"d":"0.00"},{"v":5.21610601427115,"d":"5.22"},{"v":2.3829731917908,"d":"2.38"},1,1,"up","no"]
[87403,0,"chr17","-",69103912,69115442,"ENST00000590311",5,8186,"ENSG00000154262","ABCA6","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005215(transporter activity);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0005654(nucleoplasm);GO:0055085(transmembrane transport);GO:0016887(ATPase activity);GO:0042626(ATPase activity, coupled to transmembrane movement of substances);GO:0043231(intracellular membrane-bounded organelle);GO:0006869(lipid transport)","02010(ABC transporters)","NA","NA","ATP binding cassette subfamily A member 6 [Source:HGNC Symbol;Acc:HGNC:36]",{"v":0.004426,"d":"0.00"},{"v":0.006217,"d":"0.01"},{"v":0.711918931960753,"d":"0.71"},{"v":-0.490215127736434,"d":"-0.49"},1,1,"down","no"]
[8670,0,"chr1","+",108450282,108470638,"ENST00000370040",16,2222,"ENSG00000186086","NBPF6","GO:0005737(cytoplasm)","NA","NA","NA","NBPF member 6 [Source:HGNC Symbol;Acc:HGNC:31988]",{"v":0.015484,"d":"0.02"},0,"inf","inf",1,1,"up","no"]
[71256,0,"chr16","-",28492105,28495575,"ENST00000566040",3,544,"MSTRG.5804","CLN3","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0006810(transport);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005794(Golgi apparatus);GO:0005765(lysosomal membrane);GO:0005783(endoplasmic reticulum);GO:0005886(plasma membrane);GO:0000139(Golgi membrane);GO:0005901(caveola);GO:0045121(membrane raft);GO:0005764(lysosome);GO:0005515(protein binding);GO:0005768(endosome);GO:0005802(trans-Golgi network);GO:0005769(early endosome);GO:0005770(late endosome);GO:0005776(autophagosome);GO:0030176(integral component of endoplasmic reticulum membrane);GO:0043524(negative regulation of neuron apoptotic process);GO:0051480(regulation of cytosolic calcium ion concentration);GO:0043005(neuron projection);GO:0043066(negative regulation of apoptotic process);GO:0005795(Golgi stack);GO:0005739(mitochondrion);GO:0047496(vesicle transport along microtubule);GO:0051082(unfolded protein binding);GO:0008021(synaptic vesicle);GO:0007040(lysosome organization);GO:0030163(protein catabolic process);GO:0050885(neuromuscular process controlling balance);GO:0043086(negative regulation of catalytic activity);GO:0035235(ionotropic glutamate receptor signaling pathway);GO:0006898(receptor-mediated endocytosis);GO:0006520(cellular amino acid metabolic process);GO:0007042(lysosomal lumen acidification);GO:0006672(ceramide metabolic process);GO:0097352(autophagosome maturation);GO:0045861(negative regulation of proteolysis);GO:0016485(protein processing);GO:0008306(associative learning);GO:0061024(membrane organization);GO:0001508(action potential);GO:0006681(galactosylceramide metabolic process);GO:0016236(macroautophagy);GO:0007034(vacuolar transport);GO:0001575(globoside metabolic process);GO:0006678(glucosylceramide metabolic process);GO:0006684(sphingomyelin metabolic process);GO:0015809(arginine transport);GO:0035752(lysosomal lumen pH elevation);GO:0042133(neurotransmitter metabolic process);GO:0042987(amyloid precursor protein catabolic process)","04142(Lysosome)","NA","NA","CLN3, battenin [Source:HGNC Symbol;Acc:HGNC:2074]",{"v":0.266617,"d":"0.27"},0,"inf","inf",1,1,"up","no"]
[150753,0,"chr4","+",127965306,128031290,"ENST00000398965",11,2177,"ENSG00000164074","ABHD18","GO:0005576(extracellular region)","NA","NA","NA","abhydrolase domain containing 18 [Source:HGNC Symbol;Acc:HGNC:26111]",0,{"v":0.198058,"d":"0.20"},"-inf","-inf",1,1,"down","no"]
[3029,0,"chr1","+",26186915,26188301,"ENST00000480617",3,467,"ENSG00000142675","CNKSR1","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0005515(protein binding);GO:0005886(plasma membrane);GO:0007169(transmembrane receptor protein tyrosine kinase signaling pathway);GO:0005911(cell-cell junction);GO:0005938(cell cortex);GO:0007266(Rho protein signal transduction);GO:0007265(Ras protein signal transduction);GO:0030674(protein binding, bridging)","NA","NA","NA","connector enhancer of kinase suppressor of Ras 1 [Source:HGNC Symbol;Acc:HGNC:19700]",{"v":0.11224,"d":"0.11"},{"v":0.0341,"d":"0.03"},{"v":3.29149560117302,"d":"3.29"},{"v":1.71874326970836,"d":"1.72"},1,1,"up","no"]
[161643,0,"chr5","-",177514938,177516324,"ENST00000504781",6,618,"MSTRG.12583","DDX41","GO:0003676(nucleic acid binding);GO:0005524(ATP binding);GO:0003723(RNA binding);GO:0006397(mRNA processing);GO:0008380(RNA splicing);GO:0005634(nucleus);GO:0016020(membrane);GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0016787(hydrolase activity);GO:0004386(helicase activity);GO:0005515(protein binding);GO:0005681(spliceosomal complex);GO:0030154(cell differentiation);GO:0005737(cytoplasm);GO:0005730(nucleolus);GO:0005829(cytosol);GO:0004004(ATP-dependent RNA helicase activity);GO:0010501(RNA secondary structure unwinding);GO:0008283(cell proliferation);GO:0000398(mRNA splicing, via spliceosome);GO:0006915(apoptotic process);GO:0032481(positive regulation of type I interferon production);GO:0071013(catalytic step 2 spliceosome);GO:0032479(regulation of type I interferon production);GO:0003677(DNA binding);GO:0035458(cellular response to interferon-beta);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0051607(defense response to virus);GO:0005783(endoplasmic reticulum)","NA","NA","NA","DEAD-box helicase 41 [Source:HGNC Symbol;Acc:HGNC:18674]",{"v":0.170006,"d":"0.17"},0,"inf","inf",1,1,"up","no"]
[15923,0,"chr1","+",213242060,213262816,"ENST00000491616",3,778,"ENSG00000136643","RPS6KC1","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0035091(phosphatidylinositol binding);GO:0005515(protein binding);GO:0005769(early endosome);GO:0007165(signal transduction)","NA","NA","NA","ribosomal protein S6 kinase C1 [Source:HGNC Symbol;Acc:HGNC:10439]",{"v":0.08469,"d":"0.08"},{"v":0.815352,"d":"0.82"},{"v":0.103869249109587,"d":"0.10"},{"v":-3.26715949284489,"d":"-3.27"},1,1,"down","no"]
[68291,0,"chr16","+",2206029,2209370,"ENST00000563067",7,1646,"ENSG00000167965","MLST8","GO:0005737(cytoplasm);GO:0005515(protein binding);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0032956(regulation of actin cytoskeleton organization);GO:0071902(positive regulation of protein serine/threonine kinase activity);GO:0038111(interleukin-7-mediated signaling pathway);GO:0048015(phosphatidylinositol-mediated signaling);GO:0032008(positive regulation of TOR signaling);GO:1900034(regulation of cellular response to heat);GO:0031295(T cell costimulation);GO:0031931(TORC1 complex);GO:0031932(TORC2 complex);GO:0007050(cell cycle arrest);GO:0016241(regulation of macroautophagy);GO:0038202(TORC1 signaling);GO:0043539(protein serine/threonine kinase activator activity);GO:0030838(positive regulation of actin filament polymerization);GO:0043087(regulation of GTPase activity);GO:0050731(positive regulation of peptidyl-tyrosine phosphorylation)","04151(PI3K-Akt signaling pathway);04150(mTOR signaling pathway);04140(Autophagy - animal);04136(Autophagy - other eukaryotes)","NA","NA","MTOR associated protein, LST8 homolog [Source:HGNC Symbol;Acc:HGNC:24825]",0,{"v":0.251221,"d":"0.25"},"-inf","-inf",1,1,"down","no"]
[200127,0,"chrX","-",134889123,134899534,"ENST00000370777",5,784,"ENSG00000101928","MOSPD1","GO:0048471(perinuclear region of cytoplasm);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0005737(cytoplasm);GO:0005634(nucleus);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0000122(negative regulation of transcription from RNA polymerase II promoter)","NA","NA","NA","motile sperm domain containing 1 [Source:HGNC Symbol;Acc:HGNC:25235]",0,0,1,0,1,1,"no","no"]
[151549,0,"chr4","-",152346812,152352696,"ENST00000604822",3,570,"ENSG00000109670","FBXW7","GO:0070374(positive regulation of ERK1 and ERK2 cascade);GO:0010868(negative regulation of triglyceride biosynthetic process);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016567(protein ubiquitination);GO:0005515(protein binding);GO:0005654(nucleoplasm);GO:0005730(nucleolus);GO:0042802(identical protein binding);GO:0005829(cytosol);GO:0000209(protein polyubiquitination);GO:0043687(post-translational protein modification);GO:0016032(viral process);GO:1903146(regulation of mitophagy);GO:0050821(protein stabilization);GO:1903955(positive regulation of protein targeting to mitochondrion);GO:0030332(cyclin binding);GO:2000060(positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process);GO:0031625(ubiquitin protein ligase binding);GO:0004842(ubiquitin-protein transferase activity);GO:0001944(vasculature development);GO:1901800(positive regulation of proteasomal protein catabolic process);GO:1990452(Parkin-FBXW7-Cul1 ubiquitin ligase complex);GO:0031398(positive regulation of protein ubiquitination);GO:0032880(regulation of protein localization);GO:0055088(lipid homeostasis);GO:0045741(positive regulation of epidermal growth factor-activated receptor activity);GO:0030674(protein binding, bridging);GO:0019005(SCF ubiquitin ligase complex);GO:1902806(regulation of cell cycle G1/S phase transition);GO:0031146(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process);GO:0007062(sister chromatid cohesion);GO:0032876(negative regulation of DNA endoreduplication);GO:0097027(ubiquitin-protein transferase activator activity);GO:0051443(positive regulation of ubiquitin-protein transferase activity);GO:1903378(positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway);GO:0050816(phosphothreonine residue binding);GO:0010883(regulation of lipid storage);GO:0045746(negative regulation of Notch signaling pathway);GO:2000346(negative regulation of hepatocyte proliferation);GO:2000639(negative regulation of SREBP signaling pathway)","04120(Ubiquitin mediated proteolysis)","NA","NA","F-box and WD repeat domain containing 7 [Source:HGNC Symbol;Acc:HGNC:16712]",0,{"v":0.055397,"d":"0.06"},"-inf","-inf",1,1,"down","no"]
[155915,0,"chr5","+",75547010,75582965,"ENST00000508867",6,2464,"MSTRG.12139","POLK","GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0005654(nucleoplasm);GO:0016740(transferase activity);GO:0003677(DNA binding);GO:0003684(damaged DNA binding);GO:0006281(DNA repair);GO:0006974(cellular response to DNA damage stimulus);GO:0016604(nuclear body);GO:0016779(nucleotidyltransferase activity);GO:0003887(DNA-directed DNA polymerase activity);GO:0006260(DNA replication);GO:0071897(DNA biosynthetic process);GO:0019985(translesion synthesis);GO:0006283(transcription-coupled nucleotide-excision repair);GO:0042276(error-prone translesion synthesis);GO:0006296(nucleotide-excision repair, DNA incision, 5'-to lesion);GO:0033683(nucleotide-excision repair, DNA incision);GO:0006297(nucleotide-excision repair, DNA gap filling)","03460(Fanconi anemia pathway);05200(Pathways in cancer);05202(Transcriptional misregulation in cancers);05210(Colorectal cancer);05212(Pancreatic cancer);05225(Hepatocellular carcinoma);05226(Gastric cancer);05214(Glioma);05216(Thyroid cancer);05220(Chronic myeloid leukemia);05217(Basal cell carcinoma);05218(Melanoma);05213(Endometrial cancer);05224(Breast cancer);05222(Small cell lung cancer);05223(Non-small cell lung cancer)","NA","NA","DNA polymerase kappa [Source:HGNC Symbol;Acc:HGNC:9183]",{"v":0.288629,"d":"0.29"},{"v":0.000882,"d":"0.00"},{"v":327.243764172336,"d":"327.24"},{"v":8.35422189078141,"d":"8.35"},1,1,"up","no"]
[150306,0,"chr4","-",113759115,113761451,"ENST00000505132",2,748,"ENSG00000145349","CAMK2D","GO:0005737(cytoplasm);GO:0010880(regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum);GO:0010881(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion);GO:0010666(positive regulation of cardiac muscle cell apoptotic process);GO:0005634(nucleus);GO:1902514(regulation of calcium ion transmembrane transport via high voltage-gated calcium channel);GO:0016020(membrane);GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0005886(plasma membrane);GO:0043547(positive regulation of GTPase activity);GO:0005515(protein binding);GO:0004683(calmodulin-dependent protein kinase activity);GO:0005516(calmodulin binding);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0007399(nervous system development);GO:0016529(sarcoplasmic reticulum);GO:0042383(sarcolemma);GO:0000165(MAPK cascade);GO:0030154(cell differentiation);GO:0043005(neuron projection);GO:0001558(regulation of cell growth);GO:0042803(protein homodimerization activity);GO:0044325(ion channel binding);GO:0030666(endocytic vesicle membrane);GO:0005088(Ras guanyl-nucleotide exchange factor activity);GO:0033017(sarcoplasmic reticulum membrane);GO:0060333(interferon-gamma-mediated signaling pathway);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0010649(regulation of cell communication by electrical coupling);GO:0034704(calcium channel complex);GO:0018105(peptidyl-serine phosphorylation);GO:0031432(titin binding);GO:1900034(regulation of cellular response to heat);GO:0018107(peptidyl-threonine phosphorylation);GO:0086091(regulation of heart rate by cardiac conduction);GO:0098901(regulation of cardiac muscle cell action potential);GO:0032469(endoplasmic reticulum calcium ion homeostasis);GO:0010613(positive regulation of cardiac muscle hypertrophy);GO:0046777(protein autophosphorylation);GO:0055119(relaxation of cardiac muscle);GO:0051259(protein oligomerization);GO:0002026(regulation of the force of heart contraction);GO:0060314(regulation of ryanodine-sensitive calcium-release channel activity);GO:0071277(cellular response to calcium ion);GO:0098909(regulation of cardiac muscle cell action potential involved in regulation of contraction);GO:0008016(regulation of heart contraction);GO:1901844(regulation of cell communication by electrical coupling involved in cardiac conduction);GO:1901897(regulation of relaxation of cardiac muscle);GO:0019871(sodium channel inhibitor activity);GO:2000650(negative regulation of sodium ion transmembrane transporter activity);GO:0003254(regulation of membrane depolarization);GO:0060341(regulation of cellular localization);GO:0086003(cardiac muscle cell contraction);GO:1901725(regulation of histone deacetylase activity);GO:1902306(negative regulation of sodium ion transmembrane transport);GO:0050998(nitric-oxide synthase binding);GO:0001666(response to hypoxia);GO:0010389(regulation of G2/M transition of mitotic cell cycle);GO:0014911(positive regulation of smooth muscle cell migration);GO:0030007(cellular potassium ion homeostasis);GO:0035022(positive regulation of Rac protein signal transduction);GO:0048661(positive regulation of smooth muscle cell proliferation);GO:0061049(cell growth involved in cardiac muscle cell development);GO:0070374(positive regulation of ERK1 and ERK2 cascade);GO:1903076(regulation of protein localization to plasma membrane);GO:0043234(protein complex);GO:0048471(perinuclear region of cytoplasm)","04012(ErbB signaling pathway);04310(Wnt signaling pathway);04066(HIF-1 signaling pathway);04020(Calcium signaling pathway);04024(cAMP signaling pathway);04114(Oocyte meiosis);04217(Necroptosis);04911(Insulin secretion);04922(Glucagon signaling pathway);04912(GnRH signaling pathway);04921(Oxytocin signaling pathway);04916(Melanogenesis);04925(Aldosterone synthesis and secretion);04261(Adrenergic signaling in cardiomyocytes);04971(Gastric acid secretion);04725(Cholinergic synapse);04728(Dopaminergic synapse);04720(Long-term potentiation);04722(Neurotrophin signaling pathway);04740(Olfactory transduction);04750(Inflammatory mediator regulation of TRP channels);04360(Axon guidance);04713(Circadian entrainment);05200(Pathways in cancer);05205(Proteoglycans in cancer);05214(Glioma);05031(Amphetamine addiction);05152(Tuberculosis)","NA","NA","calcium/calmodulin dependent protein kinase II delta [Source:HGNC Symbol;Acc:HGNC:1462]",{"v":0.010472,"d":"0.01"},{"v":0.017545,"d":"0.02"},{"v":0.596865203761755,"d":"0.60"},{"v":-0.744522945344288,"d":"-0.74"},1,1,"down","no"]
[97216,0,"chr19","+",12891168,12896015,"ENST00000588905",6,562,"ENSG00000105607","GCDH","GO:0016491(oxidoreductase activity);GO:0050660(flavin adenine dinucleotide binding);GO:0055114(oxidation-reduction process);GO:0016627(oxidoreductase activity, acting on the CH-CH group of donors);GO:0005739(mitochondrion);GO:0008152(metabolic process);GO:0005759(mitochondrial matrix);GO:0000062(fatty-acyl-CoA binding);GO:0003995(acyl-CoA dehydrogenase activity);GO:0004361(glutaryl-CoA dehydrogenase activity);GO:0006637(acyl-CoA metabolic process);GO:0019395(fatty acid oxidation);GO:0046949(fatty-acyl-CoA biosynthetic process);GO:0006554(lysine catabolic process);GO:0033539(fatty acid beta-oxidation using acyl-CoA dehydrogenase);GO:0006568(tryptophan metabolic process)","00071(Fatty acid degradation);00310(Lysine degradation);00380(Tryptophan metabolism)","NA","NA","glutaryl-CoA dehydrogenase [Source:HGNC Symbol;Acc:HGNC:4189]",{"v":0.107377,"d":"0.11"},0,"inf","inf",1,1,"up","no"]
[157945,0,"chr5","-",126914661,126918228,"ENST00000515241",2,719,"ENSG00000173926","MARCH3","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0016740(transferase activity);GO:0016567(protein ubiquitination);GO:0030659(cytoplasmic vesicle membrane);GO:0031410(cytoplasmic vesicle);GO:0005764(lysosome);GO:0005768(endosome);GO:0006897(endocytosis);GO:0031901(early endosome membrane)","NA","NA","NA","membrane associated ring-CH-type finger 3 [Source:HGNC Symbol;Acc:HGNC:28728]",{"v":0.129846,"d":"0.13"},0,"inf","inf",1,1,"up","no"]
[134348,0,"chr3","-",30626423,30626797,"ENST00000411661",1,375,"MSTRG.10754","AC096921.1","NA","NA","NA","NA","NA",0,0,1,0,1,1,"no","no"]
[52085,0,"chr13","+",114244562,114262979,"ENST00000484907",8,1038,"ENSG00000130177","CDC16","GO:0005737(cytoplasm);GO:0016567(protein ubiquitination);GO:0051301(cell division);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0007049(cell cycle);GO:0005815(microtubule organizing center);GO:0005819(spindle);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0031145(anaphase-promoting complex-dependent catabolic process);GO:0043161(proteasome-mediated ubiquitin-dependent protein catabolic process);GO:0051437(positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition);GO:0051436(negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle);GO:0008283(cell proliferation);GO:0042787(protein ubiquitination involved in ubiquitin-dependent protein catabolic process);GO:0051439(regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle);GO:0070979(protein K11-linked ubiquitination);GO:0005680(anaphase-promoting complex);GO:0007088(regulation of mitotic nuclear division);GO:0000278(mitotic cell cycle);GO:0005813(centrosome);GO:0005876(spindle microtubule);GO:0005634(nucleus)","04120(Ubiquitin mediated proteolysis);04110(Cell cycle);04114(Oocyte meiosis);04914(Progesterone-mediated oocyte maturation);05166(HTLV-I infection)","NA","NA","cell division cycle 16 [Source:HGNC Symbol;Acc:HGNC:1720]",{"v":0.188028,"d":"0.19"},{"v":0.061627,"d":"0.06"},{"v":3.05106527982865,"d":"3.05"},{"v":1.60931304778859,"d":"1.61"},1,1,"up","no"]
[161451,0,"chr5","-",176905658,176907307,"ENST00000505229",2,584,"MSTRG.12568","UIMC1","GO:0005634(nucleus);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0016569(covalent chromatin modification);GO:0005515(protein binding);GO:0006281(DNA repair);GO:0006974(cellular response to DNA damage stimulus);GO:0016604(nuclear body);GO:0005654(nucleoplasm);GO:0016579(protein deubiquitination);GO:0042393(histone binding);GO:0031572(G2 DNA damage checkpoint);GO:0045739(positive regulation of DNA repair);GO:0006302(double-strand break repair);GO:0006303(double-strand break repair via nonhomologous end joining);GO:0010212(response to ionizing radiation);GO:0045892(negative regulation of transcription, DNA-templated);GO:0070531(BRCA1-A complex);GO:0070537(histone H2A K63-linked deubiquitination);GO:0070530(K63-linked polyubiquitin binding)","03440(Homologous recombination)","NA","NA","ubiquitin interaction motif containing 1 [Source:HGNC Symbol;Acc:HGNC:30298]",{"v":0.139857,"d":"0.14"},{"v":0.54767,"d":"0.55"},{"v":0.255367283217996,"d":"0.26"},{"v":-1.96935439115681,"d":"-1.97"},1,1,"down","no"]
[47289,0,"chr12","+",119669424,119680841,"ENST00000540121",7,1673,"ENSG00000111725","PRKAB1","GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0007165(signal transduction);GO:0006468(protein phosphorylation);GO:0006629(lipid metabolic process);GO:0006631(fatty acid metabolic process);GO:0006633(fatty acid biosynthetic process);GO:0005515(protein binding);GO:0004679(AMP-activated protein kinase activity);GO:0019901(protein kinase binding);GO:0035878(nail development);GO:0045859(regulation of protein kinase activity);GO:0050790(regulation of catalytic activity);GO:0051291(protein heterooligomerization);GO:0005634(nucleus);GO:0031588(nucleotide-activated protein kinase complex);GO:0043234(protein complex);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0010628(positive regulation of gene expression);GO:1901796(regulation of signal transduction by p53 class mediator);GO:0004672(protein kinase activity);GO:0007050(cell cycle arrest);GO:0016241(regulation of macroautophagy);GO:0016236(macroautophagy)","04371(Apelin signaling pathway);04068(FoxO signaling pathway);04152(AMPK signaling pathway);04530(Tight junction);04910(Insulin signaling pathway);04922(Glucagon signaling pathway);04920(Adipocytokine signaling pathway);04921(Oxytocin signaling pathway);04211(Longevity regulating pathway - mammal);04213(Longevity regulating pathway - multiple species);04710(Circadian rhythm);05410(Hypertrophic cardiomyopathy (HCM));04932(Non-alcoholic fatty liver disease (NAFLD));04931(Insulin resistance)","NA","NA","protein kinase AMP-activated non-catalytic subunit beta 1 [Source:HGNC Symbol;Acc:HGNC:9378]",{"v":0.046221,"d":"0.05"},{"v":0.002115,"d":"0.00"},{"v":21.8539007092199,"d":"21.85"},{"v":4.44981890466301,"d":"4.45"},1,1,"up","no"]
[84291,0,"chr17","-",44875633,44879590,"ENST00000587957",2,503,"MSTRG.6910","EFTUD2","GO:0003723(RNA binding);GO:0006397(mRNA processing);GO:0008380(RNA splicing);GO:0005634(nucleus);GO:0016607(nuclear speck);GO:0016020(membrane);GO:0005525(GTP binding);GO:0000166(nucleotide binding);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0003924(GTPase activity);GO:0005515(protein binding);GO:0005681(spliceosomal complex);GO:0031012(extracellular matrix);GO:0000398(mRNA splicing, via spliceosome);GO:0015030(Cajal body);GO:0046540(U4/U6 x U5 tri-snRNP complex);GO:0071013(catalytic step 2 spliceosome);GO:0035690(cellular response to drug);GO:0042220(response to cocaine)","03040(Spliceosome)","NA","NA","elongation factor Tu GTP binding domain containing 2 [Source:HGNC Symbol;Acc:HGNC:30858]",{"v":0.067104,"d":"0.07"},0,"inf","inf",1,1,"up","no"]
[12533,0,"chr1","+",159961218,159979061,"ENST00000443364",4,1266,"ENSG00000224259","LINC01133","NA","NA","NA","NA","long intergenic non-protein coding RNA 1133 [Source:HGNC Symbol;Acc:HGNC:49447]",{"v":0.041959,"d":"0.04"},{"v":0.139898,"d":"0.14"},{"v":0.299925660123805,"d":"0.30"},{"v":-1.73732313770336,"d":"-1.74"},1,1,"down","no"]
[61235,0,"chr15","-",40736338,40737820,"ENST00000557831",2,954,"ENSG00000137824","RMDN3","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005739(mitochondrion);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0006915(apoptotic process);GO:0005741(mitochondrial outer membrane);GO:0030154(cell differentiation);GO:0005874(microtubule);GO:0000922(spindle pole);GO:0005819(spindle);GO:0031966(mitochondrial membrane);GO:0006874(cellular calcium ion homeostasis)","NA","NA","NA","regulator of microtubule dynamics 3 [Source:HGNC Symbol;Acc:HGNC:25550]",0,{"v":2.72E-4,"d":"0.00"},"-inf","-inf",1,1,"down","no"]
[59961,0,"chr15","-",23005799,23008797,"ENST00000613552",3,558,"ENSG00000275835","TUBGCP5","GO:0005737(cytoplasm);GO:0005856(cytoskeleton);GO:0005874(microtubule);GO:0000226(microtubule cytoskeleton organization);GO:0005815(microtubule organizing center);GO:0043015(gamma-tubulin binding);GO:0007020(microtubule nucleation);GO:0000922(spindle pole);GO:0005829(cytosol);GO:0005813(centrosome);GO:0008017(microtubule binding);GO:0005200(structural constituent of cytoskeleton);GO:0031122(cytoplasmic microtubule organization);GO:0090307(mitotic spindle assembly);GO:0008274(gamma-tubulin ring complex);GO:0051415(interphase microtubule nucleation by interphase microtubule organizing center);GO:0000923(equatorial microtubule organizing center);GO:0051298(centrosome duplication);GO:0051321(meiotic cell cycle);GO:0051011(microtubule minus-end binding)","NA","NA","NA","tubulin gamma complex associated protein 5 [Source:HGNC Symbol;Acc:HGNC:18600]",{"v":0.239036,"d":"0.24"},{"v":0.230092,"d":"0.23"},{"v":1.03887140795856,"d":"1.04"},{"v":0.0550170877533461,"d":"0.06"},1,1,"up","no"]
[22191,0,"chr10","+",90871952,90903262,"ENST00000413330",13,1004,"MSTRG.1862","RPP30","GO:0003723(RNA binding);GO:0005634(nucleus);GO:0008033(tRNA processing);GO:0016787(hydrolase activity);GO:0003824(catalytic activity);GO:0005515(protein binding);GO:0005730(nucleolus);GO:0004540(ribonuclease activity);GO:0005654(nucleoplasm);GO:0006364(rRNA processing);GO:0004526(ribonuclease P activity);GO:0001682(tRNA 5'-leader removal);GO:0090502(RNA phosphodiester bond hydrolysis, endonucleolytic);GO:0000172(ribonuclease MRP complex);GO:0005655(nucleolar ribonuclease P complex);GO:0030681(multimeric ribonuclease P complex);GO:0090501(RNA phosphodiester bond hydrolysis)","03013(RNA transport);03008(Ribosome biogenesis in eukaryotes)","K03539","EC:3.1.26.5","ribonuclease P/MRP subunit p30 [Source:HGNC Symbol;Acc:HGNC:17688]",0,0,1,0,1,1,"no","no"]
[25292,0,"chr11","+",1919748,1938706,"ENST00000381558",16,1258,"ENSG00000130595","TNNT3","GO:0003779(actin binding);GO:0005861(troponin complex);GO:0006937(regulation of muscle contraction);GO:0005829(cytosol);GO:0003009(skeletal muscle contraction);GO:0048306(calcium-dependent protein binding);GO:0006942(regulation of striated muscle contraction);GO:0030049(muscle filament sliding);GO:0005523(tropomyosin binding);GO:0043462(regulation of ATPase activity);GO:0030172(troponin C binding);GO:0030899(calcium-dependent ATPase activity);GO:0031013(troponin I binding)","NA","NA","NA","troponin T3, fast skeletal type [Source:HGNC Symbol;Acc:HGNC:11950]",{"v":0.07679,"d":"0.08"},{"v":0.060682,"d":"0.06"},{"v":1.26544939191193,"d":"1.27"},{"v":0.339649812073159,"d":"0.34"},1,1,"up","no"]
[37345,0,"chr12","+",1617056,1647211,"ENST00000310594",5,2184,"MSTRG.3002","WNT5B","GO:0005102(receptor binding);GO:0005576(extracellular region);GO:0007275(multicellular organism development);GO:0016055(Wnt signaling pathway);GO:0005578(proteinaceous extracellular matrix);GO:0005615(extracellular space);GO:0005886(plasma membrane);GO:0070062(extracellular exosome);GO:0045444(fat cell differentiation);GO:0030335(positive regulation of cell migration);GO:0030182(neuron differentiation);GO:0005788(endoplasmic reticulum lumen);GO:0030666(endocytic vesicle membrane);GO:0005796(Golgi lumen);GO:0002062(chondrocyte differentiation);GO:0005109(frizzled binding);GO:0045165(cell fate commitment);GO:0071300(cellular response to retinoic acid);GO:0070307(lens fiber cell development);GO:0042060(wound healing);GO:0045600(positive regulation of fat cell differentiation);GO:0090090(negative regulation of canonical Wnt signaling pathway);GO:0009986(cell surface)","04310(Wnt signaling pathway);04390(Hippo signaling pathway);04150(mTOR signaling pathway);04550(Signaling pathways regulating pluripotency of stem cells);04916(Melanogenesis);04360(Axon guidance);05200(Pathways in cancer);05205(Proteoglycans in cancer);05225(Hepatocellular carcinoma);05226(Gastric cancer);05217(Basal cell carcinoma);05224(Breast cancer);05166(HTLV-I infection);05165(Human papillomavirus infection)","K00444","NA","Wnt family member 5B [Source:HGNC Symbol;Acc:HGNC:16265]",{"v":0.266417,"d":"0.27"},0,"inf","inf",1,1,"up","no"]
[17580,0,"chr1","-",244853467,244860536,"ENST00000638716",11,2640,"MSTRG.1497","HNRNPU","GO:0005634(nucleus);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0003723(RNA binding);GO:0006397(mRNA processing);GO:0008380(RNA splicing);GO:0005737(cytoplasm);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0005654(nucleoplasm);GO:0003677(DNA binding);GO:0030529(intracellular ribonucleoprotein complex);GO:0005515(protein binding);GO:0005681(spliceosomal complex);GO:0048511(rhythmic process);GO:0001047(core promoter binding);GO:0031012(extracellular matrix);GO:0000398(mRNA splicing, via spliceosome);GO:0009986(cell surface);GO:0032922(circadian regulation of gene expression);GO:0036464(cytoplasmic ribonucleoprotein granule);GO:0070034(telomerase RNA binding);GO:0005697(telomerase holoenzyme complex);GO:0016070(RNA metabolic process);GO:0006396(RNA processing);GO:0071013(catalytic step 2 spliceosome);GO:0001649(osteoblast differentiation);GO:0070934(CRD-mediated mRNA stabilization);GO:0070937(CRD-mediated mRNA stability complex);GO:0032211(negative regulation of telomere maintenance via telomerase);GO:0034046(poly(G) binding);GO:0035326(enhancer binding);GO:0043021(ribonucleoprotein complex binding);GO:0010628(positive regulation of gene expression);GO:0055013(cardiac muscle cell development);GO:0071549(cellular response to dexamethasone stimulus);GO:2000373(positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity)","03040(Spliceosome)","NA","NA","heterogeneous nuclear ribonucleoprotein U [Source:HGNC Symbol;Acc:HGNC:5048]",{"v":0.191185,"d":"0.19"},{"v":0.071532,"d":"0.07"},{"v":2.67271990158251,"d":"2.67"},{"v":1.41830865248125,"d":"1.42"},1,1,"up","no"]
[177142,0,"chr7","-",101210356,101211103,"ENST00000466881",2,661,"MSTRG.13840","PLOD3","GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0005783(endoplasmic reticulum);GO:0005506(iron ion binding);GO:0016705(oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen);GO:0031418(L-ascorbic acid binding);GO:0008475(procollagen-lysine 5-dioxygenase activity);GO:0016020(membrane);GO:0046872(metal ion binding);GO:0005515(protein binding);GO:0051213(dioxygenase activity);GO:0005789(endoplasmic reticulum membrane);GO:0070062(extracellular exosome);GO:0005794(Golgi apparatus);GO:0017185(peptidyl-lysine hydroxylation);GO:0046947(hydroxylysine biosynthetic process);GO:0030867(rough endoplasmic reticulum membrane);GO:0033823(procollagen glucosyltransferase activity);GO:0050211(procollagen galactosyltransferase activity);GO:0001701(in utero embryonic development);GO:0001886(endothelial cell morphogenesis);GO:0006493(protein O-linked glycosylation);GO:0008104(protein localization);GO:0021915(neural tube development);GO:0030199(collagen fibril organization);GO:0032870(cellular response to hormone stimulus);GO:0032963(collagen metabolic process);GO:0042311(vasodilation);GO:0048730(epidermis morphogenesis);GO:0060425(lung morphogenesis);GO:0070831(basement membrane assembly);GO:0005802(trans-Golgi network);GO:0031012(extracellular matrix)","00310(Lysine degradation);00514(Other types of O-glycan biosynthesis)","NA","NA","procollagen-lysine,2-oxoglutarate 5-dioxygenase 3 [Source:HGNC Symbol;Acc:HGNC:9083]",{"v":0.408148,"d":"0.41"},{"v":0.086439,"d":"0.09"},{"v":4.7218038154074,"d":"4.72"},{"v":2.23933810077481,"d":"2.24"},1,1,"up","no"]
[67703,0,"chr16","-",785983,788381,"ENST00000565377",6,940,"ENSG00000007376","RPUSD1","GO:0003723(RNA binding);GO:0009982(pseudouridine synthase activity);GO:0001522(pseudouridine synthesis);GO:0009451(RNA modification);GO:0003674(molecular_function);GO:0008150(biological_process);GO:0005575(cellular_component);GO:0031119(tRNA pseudouridine synthesis);GO:0019239(deaminase activity);GO:0000455(enzyme-directed rRNA pseudouridine synthesis)","NA","NA","NA","RNA pseudouridylate synthase domain containing 1 [Source:HGNC Symbol;Acc:HGNC:14173]",{"v":0.178394,"d":"0.18"},{"v":0.100613,"d":"0.10"},{"v":1.77307107431445,"d":"1.77"},{"v":0.826250368445184,"d":"0.83"},1,1,"up","no"]
[83248,0,"chr17","-",41346092,41350812,"ENST00000007735",7,1287,"ENSG00000006059","KRT33A","GO:0005198(structural molecule activity);GO:0005882(intermediate filament);GO:0005615(extracellular space);GO:0005829(cytosol);GO:0031424(keratinization);GO:0070268(cornification)","NA","NA","NA","keratin 33A [Source:HGNC Symbol;Acc:HGNC:6450]",0,0,1,0,1,1,"no","no"]
[95422,0,"chr19","+",6067953,6077119,"ENST00000587759",2,567,"MSTRG.7730","AC011444.2","NA","NA","NA","NA","NA",{"v":0.045912,"d":"0.05"},{"v":0.02764,"d":"0.03"},{"v":1.66107091172214,"d":"1.66"},{"v":0.732113663791648,"d":"0.73"},1,1,"up","no"]
[13540,0,"chr1","-",170462209,170532647,"ENST00000456083",3,521,"ENSG00000231407","AL354732.1","NA","NA","NA","NA","NA",{"v":0.112964,"d":"0.11"},{"v":0.063915,"d":"0.06"},{"v":1.76740984119534,"d":"1.77"},{"v":0.821636622402188,"d":"0.82"},1,1,"up","no"]
[21251,0,"chr10","+",73496290,73504717,"ENST00000610317",5,691,"ENSG00000221817","PPP3CB-AS1","NA","NA","NA","NA","PPP3CB antisense RNA 1 (head to head) [Source:HGNC Symbol;Acc:HGNC:50750]",0,{"v":0.026671,"d":"0.03"},"-inf","-inf",1,1,"down","no"]
[111912,0,"chr2","-",86143932,86195002,"ENST00000254636",15,2613,"MSTRG.8881","IMMT","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005739(mitochondrion);GO:0005743(mitochondrial inner membrane);GO:0003723(RNA binding);GO:0005515(protein binding);GO:0061617(MICOS complex);GO:0008150(biological_process);GO:0042407(cristae formation);GO:0051560(mitochondrial calcium ion homeostasis);GO:0043209(myelin sheath)","NA","NA","NA","inner membrane mitochondrial protein [Source:HGNC Symbol;Acc:HGNC:6047]",{"v":0.106206,"d":"0.11"},{"v":0.596919,"d":"0.60"},{"v":0.177923637880516,"d":"0.18"},{"v":-2.49066990363256,"d":"-2.49"},1,1,"down","no"]
[58476,0,"chr14","-",100292781,100306517,"ENST00000556868",5,1067,"MSTRG.4674","SLC25A29","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0055085(transmembrane transport);GO:0005743(mitochondrial inner membrane);GO:0005739(mitochondrion);GO:1990822(basic amino acid transmembrane transport);GO:1903826(arginine transmembrane transport);GO:0015171(amino acid transmembrane transporter activity);GO:0006839(mitochondrial transport);GO:1902616(acyl carnitine transmembrane transport);GO:0006865(amino acid transport);GO:0015174(basic amino acid transmembrane transporter activity);GO:0005289(high-affinity arginine transmembrane transporter activity);GO:0005292(high-affinity lysine transmembrane transporter activity);GO:0015227(acyl carnitine transmembrane transporter activity);GO:0006844(acyl carnitine transport);GO:0015822(ornithine transport);GO:0089709(L-histidine transmembrane transport);GO:1903400(L-arginine transmembrane transport);GO:1903401(L-lysine transmembrane transport);GO:1990575(mitochondrial L-ornithine transmembrane transport)","NA","NA","NA","solute carrier family 25 member 29 [Source:HGNC Symbol;Acc:HGNC:20116]",{"v":0.038538,"d":"0.04"},0,"inf","inf",1,1,"up","no"]
[186929,0,"chr8","+",124271683,124277584,"ENST00000517482",3,553,"ENSG00000253227","AC090192.2","NA","NA","NA","NA","NA",{"v":0.082062,"d":"0.08"},0,"inf","inf",1,1,"up","no"]
[141148,0,"chr3","+",141231829,141317922,"ENST00000637751",9,4654,"ENSG00000155893","PXYLP1","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016787(hydrolase activity);GO:0005794(Golgi apparatus);GO:0016311(dephosphorylation);GO:0000139(Golgi membrane);GO:0003993(acid phosphatase activity);GO:0005515(protein binding);GO:0016791(phosphatase activity);GO:0006024(glycosaminoglycan biosynthetic process);GO:0050650(chondroitin sulfate proteoglycan biosynthetic process);GO:0010909(positive regulation of heparan sulfate proteoglycan biosynthetic process)","NA","NA","NA","2-phosphoxylose phosphatase 1 [Source:HGNC Symbol;Acc:HGNC:26303]",{"v":0.014875,"d":"0.01"},{"v":0.010935,"d":"0.01"},{"v":1.36031092821216,"d":"1.36"},{"v":0.443936448034575,"d":"0.44"},1,1,"up","no"]
[81920,0,"chr17","-",32141226,32143135,"ENST00000398832",2,1599,"MSTRG.6662","AC116407.1","NA","NA","NA","NA","NA",{"v":0.100426,"d":"0.10"},{"v":0.031827,"d":"0.03"},{"v":3.15537122568888,"d":"3.16"},{"v":1.65780974655643,"d":"1.66"},1,1,"up","no"]
[164655,0,"chr6","+",31760720,31763144,"ENST00000491552",7,706,"MSTRG.12888","MSH5-SAPCD1","GO:0005634(nucleus);GO:0005524(ATP binding);GO:0003677(DNA binding);GO:0006281(DNA repair);GO:0006974(cellular response to DNA damage stimulus);GO:0030983(mismatched DNA binding);GO:0006298(mismatch repair);GO:0032301(MutSalpha complex)","NA","NA","NA","MSH5-SAPCD1 readthrough (NMD candidate) [Source:HGNC Symbol;Acc:HGNC:41994]",0,{"v":0.267569,"d":"0.27"},"-inf","-inf",1,1,"down","no"]
[99841,0,"chr19","+",34677639,34683049,"ENST00000512455",3,568,"ENSG00000089335","ZNF302","GO:0003676(nucleic acid binding);GO:0006355(regulation of transcription, DNA-templated);GO:0005622(intracellular);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0003700(transcription factor activity, sequence-specific DNA binding)","NA","NA","NA","zinc finger protein 302 [Source:HGNC Symbol;Acc:HGNC:13848]",{"v":0.007863,"d":"0.01"},{"v":0.314351,"d":"0.31"},{"v":0.0250134403898826,"d":"0.03"},{"v":-5.32115268795087,"d":"-5.32"},1,1,"down","no"]
[174679,0,"chr7","+",66921844,66945032,"ENST00000413593",3,637,"MSTRG.13661","TMEM248","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005515(protein binding)","NA","NA","NA","transmembrane protein 248 [Source:HGNC Symbol;Acc:HGNC:25476]",{"v":0.250172,"d":"0.25"},{"v":0.193802,"d":"0.19"},{"v":1.29086387137388,"d":"1.29"},{"v":0.368336868616618,"d":"0.37"},1,1,"up","no"]
[92217,0,"chr18","-",47115131,47150459,"ENST00000590815",6,809,"ENSG00000167220","HDHD2","GO:0046872(metal ion binding);GO:0005515(protein binding);GO:0008150(biological_process);GO:0070062(extracellular exosome);GO:0019899(enzyme binding);GO:0016791(phosphatase activity);GO:0016311(dephosphorylation)","NA","NA","NA","haloacid dehalogenase like hydrolase domain containing 2 [Source:HGNC Symbol;Acc:HGNC:25364]",{"v":0.124182,"d":"0.12"},{"v":0.004166,"d":"0.00"},{"v":29.8084493518963,"d":"29.81"},{"v":4.89764942256411,"d":"4.90"},1,1,"up","no"]
[133131,0,"chr3","+",9810602,9818921,"ENST00000422738",5,545,"MSTRG.10649","TTLL3","GO:0070735(protein-glycine ligase activity);GO:0018094(protein polyglycylation);GO:0005524(ATP binding);GO:0003824(catalytic activity);GO:0006464(cellular protein modification process);GO:0005737(cytoplasm);GO:0000166(nucleotide binding);GO:0005856(cytoskeleton);GO:0042995(cell projection);GO:0016874(ligase activity);GO:0005874(microtubule);GO:0060271(cilium assembly);GO:0005929(cilium);GO:0005829(cytosol);GO:0015630(microtubule cytoskeleton);GO:0005930(axoneme);GO:0070736(protein-glycine ligase activity, initiating);GO:0035082(axoneme assembly)","NA","NA","NA","tubulin tyrosine ligase like 3 [Source:HGNC Symbol;Acc:HGNC:24483]",0,0,1,0,1,1,"no","no"]
[25197,0,"chr11","-",1554044,1571920,"ENST00000397374",7,4480,"ENSG00000184545","DUSP8","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016787(hydrolase activity);GO:0004725(protein tyrosine phosphatase activity);GO:0008138(protein tyrosine/serine/threonine phosphatase activity);GO:0016791(phosphatase activity);GO:0006470(protein dephosphorylation);GO:0016311(dephosphorylation);GO:0035335(peptidyl-tyrosine dephosphorylation);GO:0004721(phosphoprotein phosphatase activity);GO:0017017(MAP kinase tyrosine/serine/threonine phosphatase activity);GO:0000188(inactivation of MAPK activity)","04010(MAPK signaling pathway)","K04459","EC:3.1.3.16;EC:3.1.3.48","dual specificity phosphatase 8 [Source:HGNC Symbol;Acc:HGNC:3074]",{"v":0.602278,"d":"0.60"},{"v":0.101849,"d":"0.10"},{"v":5.9134404854245,"d":"5.91"},{"v":2.56399774581025,"d":"2.56"},1,1,"up","no"]
[25262,0,"chr11","+",1840218,1840735,"ENST00000468473",2,435,"ENSG00000130598","TNNI2","GO:0005634(nucleus);GO:0003779(actin binding);GO:0045893(positive regulation of transcription, DNA-templated);GO:0005861(troponin complex);GO:0005515(protein binding);GO:0005829(cytosol);GO:0003009(skeletal muscle contraction);GO:0030049(muscle filament sliding);GO:0060048(cardiac muscle contraction);GO:0031014(troponin T binding);GO:0006937(regulation of muscle contraction)","NA","NA","NA","troponin I2, fast skeletal type [Source:HGNC Symbol;Acc:HGNC:11946]",{"v":0.963526,"d":"0.96"},{"v":1.716601,"d":"1.72"},{"v":0.56129875259306,"d":"0.56"},{"v":-0.83315924176924,"d":"-0.83"},1,1,"down","no"]
[94127,0,"chr19","+",1067327,1086626,"ENST00000590214",23,4191,"MSTRG.7595","ARHGAP45","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0046872(metal ion binding);GO:0035556(intracellular signal transduction);GO:0007165(signal transduction);GO:0005886(plasma membrane);GO:0043547(positive regulation of GTPase activity);GO:0042995(cell projection);GO:0005515(protein binding);GO:0005096(GTPase activator activity);GO:0005576(extracellular region);GO:0005829(cytosol);GO:0051056(regulation of small GTPase mediated signal transduction);GO:0032587(ruffle membrane);GO:0043312(neutrophil degranulation);GO:0034774(secretory granule lumen);GO:0035578(azurophil granule lumen);GO:0005622(intracellular)","NA","NA","NA","Rho GTPase activating protein 45 [Source:HGNC Symbol;Acc:HGNC:17102]",{"v":0.101966,"d":"0.10"},{"v":0.010334,"d":"0.01"},{"v":9.86704083607509,"d":"9.87"},{"v":3.30261747969422,"d":"3.30"},1,1,"up","no"]
[115701,0,"chr2","+",161160349,161235381,"ENST00000402568",8,878,"MSTRG.9193","TANK","GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0005829(cytosol);GO:0005515(protein binding);GO:0006508(proteolysis);GO:0006974(cellular response to DNA damage stimulus);GO:0043234(protein complex);GO:0071347(cellular response to interleukin-1);GO:0071356(cellular response to tumor necrosis factor);GO:0004843(thiol-dependent ubiquitin-specific protease activity);GO:0016032(viral process);GO:0031625(ubiquitin protein ligase binding);GO:0007165(signal transduction);GO:0035666(TRIF-dependent toll-like receptor signaling pathway);GO:0043124(negative regulation of I-kappaB kinase/NF-kappaB signaling);GO:0071479(cellular response to ionizing radiation);GO:1903003(positive regulation of protein deubiquitination);GO:0035800(deubiquitinase activator activity);GO:2000158(positive regulation of ubiquitin-specific protease activity);GO:0007249(I-kappaB kinase/NF-kappaB signaling)","04621(NOD-like receptor signaling pathway);04622(RIG-I-like receptor signaling pathway)","NA","NA","TRAF family member associated NFKB activator [Source:HGNC Symbol;Acc:HGNC:11562]",{"v":0.098621,"d":"0.10"},{"v":0.078724,"d":"0.08"},{"v":1.25274376302017,"d":"1.25"},{"v":0.325091355103537,"d":"0.33"},1,1,"up","no"]
[26392,0,"chr11","-",8717832,8726319,"ENST00000527870",2,308,"MSTRG.2230","ST5","GO:0043547(positive regulation of GTPase activity);GO:0005085(guanyl-nucleotide exchange factor activity);GO:0017112(Rab guanyl-nucleotide exchange factor activity)","NA","NA","NA","suppression of tumorigenicity 5 [Source:HGNC Symbol;Acc:HGNC:11350]",0,0,1,0,1,1,"no","no"]
[89085,0,"chr17","-",80216723,80220333,"ENST00000571075",2,578,"MSTRG.7305","SGSH","GO:0003824(catalytic activity);GO:0008152(metabolic process);GO:0008484(sulfuric ester hydrolase activity);GO:0046872(metal ion binding);GO:0016787(hydrolase activity);GO:0005764(lysosome);GO:0070062(extracellular exosome);GO:0043202(lysosomal lumen);GO:0006027(glycosaminoglycan catabolic process);GO:0030200(heparan sulfate proteoglycan catabolic process);GO:0016250(N-sulfoglucosamine sulfohydrolase activity)","00531(Glycosaminoglycan degradation);04142(Lysosome)","NA","NA","N-sulfoglucosamine sulfohydrolase [Source:HGNC Symbol;Acc:HGNC:10818]",{"v":0.046269,"d":"0.05"},{"v":0.050791,"d":"0.05"},{"v":0.91096847866748,"d":"0.91"},{"v":-0.134526960132126,"d":"-0.13"},1,1,"down","no"]
[52295,0,"chr14","+",20343615,20357904,"ENST00000250416",16,1886,"MSTRG.4130","PARP2","GO:0005634(nucleus);GO:0005730(nucleolus);GO:0016740(transferase activity);GO:0003677(DNA binding);GO:0016757(transferase activity, transferring glycosyl groups);GO:0005515(protein binding);GO:0003950(NAD+ ADP-ribosyltransferase activity);GO:0006471(protein ADP-ribosylation);GO:0005737(cytoplasm);GO:0006281(DNA repair);GO:0005654(nucleoplasm);GO:0003910(DNA ligase (ATP) activity);GO:1990404(protein ADP-ribosylase activity);GO:0006273(lagging strand elongation);GO:0018312(peptidyl-serine ADP-ribosylation);GO:0051103(DNA ligation involved in DNA repair);GO:0006284(base-excision repair);GO:0097191(extrinsic apoptotic signaling pathway)","03410(Base excision repair);04210(Apoptosis);04217(Necroptosis)","K10798","EC:2.4.2.30","poly(ADP-ribose) polymerase 2 [Source:HGNC Symbol;Acc:HGNC:272]",0,{"v":0.14217,"d":"0.14"},"-inf","-inf",1,1,"down","no"]
[140163,0,"chr3","+",127672947,127677073,"ENST00000475265",6,1108,"MSTRG.11156","ABTB1","GO:0005737(cytoplasm);GO:0006412(translation);GO:0005730(nucleolus);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0003746(translation elongation factor activity);GO:0006414(translational elongation);GO:0031625(ubiquitin protein ligase binding);GO:0043161(proteasome-mediated ubiquitin-dependent protein catabolic process);GO:0030162(regulation of proteolysis);GO:0042787(protein ubiquitination involved in ubiquitin-dependent protein catabolic process);GO:0019005(SCF ubiquitin ligase complex)","NA","NA","NA","ankyrin repeat and BTB domain containing 1 [Source:HGNC Symbol;Acc:HGNC:18275]",{"v":0.077019,"d":"0.08"},0,"inf","inf",1,1,"up","no"]
[4533,0,"chr1","+",39284091,39285330,"ENST00000472385",3,500,"MSTRG.449","MACF1","GO:0003779(actin binding);GO:0005509(calcium ion binding);GO:0005856(cytoskeleton);GO:0008017(microtubule binding);GO:0016055(Wnt signaling pathway);GO:0016887(ATPase activity);GO:0003723(RNA binding);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0046872(metal ion binding);GO:0005794(Golgi apparatus);GO:0005886(plasma membrane);GO:0042995(cell projection);GO:0005515(protein binding);GO:0005874(microtubule);GO:0045296(cadherin binding);GO:0051015(actin filament binding);GO:0045773(positive regulation of axon extension);GO:0032587(ruffle membrane);GO:0042060(wound healing);GO:0051893(regulation of focal adhesion assembly);GO:0032886(regulation of microtubule-based process);GO:0030177(positive regulation of Wnt signaling pathway);GO:0010632(regulation of epithelial cell migration);GO:0043001(Golgi to plasma membrane protein transport);GO:0016021(integral component of membrane);GO:0030054(cell junction);GO:0015629(actin cytoskeleton)","NA","NA","NA","microtubule-actin crosslinking factor 1 [Source:HGNC Symbol;Acc:HGNC:13664]",{"v":0.000679,"d":"0.00"},0,"inf","inf",1,1,"up","no"]
[78372,0,"chr17","-",6423737,6435132,"ENST00000381128",6,2964,"ENSG00000129221","AIPL1","GO:0007601(visual perception);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005515(protein binding);GO:0050896(response to stimulus);GO:0001895(retina homeostasis);GO:0007603(phototransduction, visible light);GO:0030823(regulation of cGMP metabolic process);GO:0043066(negative regulation of apoptotic process);GO:0001917(photoreceptor inner segment);GO:0051082(unfolded protein binding);GO:0001918(farnesylated protein binding);GO:0018343(protein farnesylation)","NA","NA","NA","aryl hydrocarbon receptor interacting protein like 1 [Source:HGNC Symbol;Acc:HGNC:359]",0,0,1,0,1,1,"no","no"]
[52423,0,"chr14","-",20801228,20803278,"ENST00000397967",2,1348,"ENSG00000129538","RNASE1","GO:0003676(nucleic acid binding);GO:0016787(hydrolase activity);GO:0090305(nucleic acid phosphodiester bond hydrolysis);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0004519(endonuclease activity);GO:0090502(RNA phosphodiester bond hydrolysis, endonucleolytic);GO:0004518(nuclease activity);GO:0070062(extracellular exosome);GO:0004540(ribonuclease activity);GO:0004522(ribonuclease A activity);GO:0090501(RNA phosphodiester bond hydrolysis)","NA","NA","NA","ribonuclease A family member 1, pancreatic [Source:HGNC Symbol;Acc:HGNC:10044]",{"v":0.392041,"d":"0.39"},{"v":0.854769,"d":"0.85"},{"v":0.458651401723741,"d":"0.46"},{"v":-1.12453004599496,"d":"-1.12"},1,1,"down","no"]
[53646,0,"chr14","+",24232686,24238387,"ENST00000558865",7,735,"MSTRG.4356","GMPR2","GO:0046872(metal ion binding);GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0003824(catalytic activity);GO:0003920(GMP reductase activity);GO:0006144(purine nucleobase metabolic process);GO:0009117(nucleotide metabolic process);GO:1902560(GMP reductase complex);GO:0005829(cytosol);GO:0043101(purine-containing compound salvage);GO:0046037(GMP metabolic process);GO:0006163(purine nucleotide metabolic process);GO:0006164(purine nucleotide biosynthetic process);GO:0003938(IMP dehydrogenase activity)","00230(Purine metabolism)","NA","NA","guanosine monophosphate reductase 2 [Source:HGNC Symbol;Acc:HGNC:4377]",0,{"v":0.895243,"d":"0.90"},"-inf","-inf",1,1,"down","no"]
[41180,0,"chr12","-",49103081,49107011,"ENST00000551169",7,771,"ENSG00000139636","LMBR1L","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005886(plasma membrane);GO:0006897(endocytosis)","NA","NA","NA","limb development membrane protein 1 like [Source:HGNC Symbol;Acc:HGNC:18268]",{"v":0.014436,"d":"0.01"},0,"inf","inf",1,1,"up","no"]
[118255,0,"chr2","+",203238982,203297014,"ENST00000461371",11,1359,"ENSG00000119004","CYP20A1","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0046872(metal ion binding);GO:0004497(monooxygenase activity);GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0005506(iron ion binding);GO:0016705(oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen);GO:0020037(heme binding)","NA","NA","NA","cytochrome P450 family 20 subfamily A member 1 [Source:HGNC Symbol;Acc:HGNC:20576]",{"v":0.052103,"d":"0.05"},{"v":0.449567,"d":"0.45"},{"v":0.115895962114657,"d":"0.12"},{"v":-3.10909779203426,"d":"-3.11"},1,1,"down","no"]
[29940,0,"chr11","+",61362387,61368583,"ENST00000507563",4,1134,"MSTRG.2443","TMEM138","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0042995(cell projection);GO:0060271(cilium assembly);GO:0005929(cilium);GO:0030030(cell projection organization);GO:0005773(vacuole);GO:0005774(vacuolar membrane)","NA","NA","NA","transmembrane protein 138 [Source:HGNC Symbol;Acc:HGNC:26944]",{"v":0.305721,"d":"0.31"},{"v":0.303635,"d":"0.30"},{"v":1.00687009073394,"d":"1.01"},{"v":0.00987755470111546,"d":"0.01"},1,1,"up","no"]
[178696,0,"chr7","+",130116445,130117666,"ENST00000495724",2,370,"ENSG00000128607","KLHDC10","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005654(nucleoplasm);GO:0005515(protein binding)","NA","NA","NA","kelch domain containing 10 [Source:HGNC Symbol;Acc:HGNC:22194]",{"v":0.004992,"d":"0.00"},{"v":0.208513,"d":"0.21"},{"v":0.0239409533218552,"d":"0.02"},{"v":-5.38437558864914,"d":"-5.38"},1,1,"down","no"]
[145076,0,"chr4","-",968291,986895,"ENST00000510286",5,473,"MSTRG.11488","DGKQ","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016607(nuclear speck);GO:0016020(membrane);GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0035556(intracellular signal transduction);GO:0007165(signal transduction);GO:0008152(metabolic process);GO:0003951(NAD+ kinase activity);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0005856(cytoskeleton);GO:0007186(G-protein coupled receptor signaling pathway);GO:0004143(diacylglycerol kinase activity);GO:0007205(protein kinase C-activating G-protein coupled receptor signaling pathway);GO:0005515(protein binding);GO:0016363(nuclear matrix);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0007171(activation of transmembrane receptor protein tyrosine kinase activity);GO:0030168(platelet activation);GO:0019933(cAMP-mediated signaling);GO:0019900(kinase binding);GO:0012506(vesicle membrane);GO:0010628(positive regulation of gene expression);GO:0010629(negative regulation of gene expression);GO:0018105(peptidyl-serine phosphorylation);GO:0046339(diacylglycerol metabolic process);GO:0046834(lipid phosphorylation);GO:0070528(protein kinase C signaling);GO:0005768(endosome);GO:0070493(thrombin-activated receptor signaling pathway);GO:0046486(glycerolipid metabolic process);GO:0030297(transmembrane receptor protein tyrosine kinase activator activity);GO:0033613(activating transcription factor binding);GO:0043274(phospholipase binding);GO:0006111(regulation of gluconeogenesis);GO:0006654(phosphatidic acid biosynthetic process);GO:0008277(regulation of G-protein coupled receptor protein signaling pathway);GO:0010801(negative regulation of peptidyl-threonine phosphorylation);GO:0033198(response to ATP);GO:0050731(positive regulation of peptidyl-tyrosine phosphorylation);GO:0051591(response to cAMP);GO:0090181(regulation of cholesterol metabolic process);GO:1903432(regulation of TORC1 signaling);GO:2000064(regulation of cortisol biosynthetic process);GO:2000182(regulation of progesterone biosynthetic process);GO:0005622(intracellular)","00561(Glycerolipid metabolism);00564(Glycerophospholipid metabolism);04070(Phosphatidylinositol signaling system);04072(Phospholipase D signaling pathway);05231(Choline metabolism in cancer)","NA","NA","diacylglycerol kinase theta [Source:HGNC Symbol;Acc:HGNC:2856]",{"v":0.109466,"d":"0.11"},{"v":0.074203,"d":"0.07"},{"v":1.47522337371804,"d":"1.48"},{"v":0.560933419393965,"d":"0.56"},1,1,"up","no"]
[88868,0,"chr17","-",78787466,78798455,"ENST00000591052",3,427,"MSTRG.7296","USP36","GO:0003723(RNA binding);GO:0005634(nucleus);GO:0016607(nuclear speck);GO:0005730(nucleolus);GO:0016579(protein deubiquitination);GO:0016787(hydrolase activity);GO:0008233(peptidase activity);GO:0008234(cysteine-type peptidase activity);GO:0006508(proteolysis);GO:0006511(ubiquitin-dependent protein catabolic process);GO:0036459(thiol-dependent ubiquitinyl hydrolase activity);GO:1903146(regulation of mitophagy);GO:0004843(thiol-dependent ubiquitin-specific protease activity);GO:1903955(positive regulation of protein targeting to mitochondrion)","NA","NA","NA","ubiquitin specific peptidase 36 [Source:HGNC Symbol;Acc:HGNC:20062]",0,0,1,0,1,1,"no","no"]
[157821,0,"chr5","+",123552965,123557564,"ENST00000514131",2,253,"ENSG00000151292","CSNK1G3","GO:0005737(cytoplasm);GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0016055(Wnt signaling pathway);GO:0005634(nucleus);GO:0008360(regulation of cell shape);GO:0007165(signal transduction);GO:0006464(cellular protein modification process);GO:0006897(endocytosis);GO:0018105(peptidyl-serine phosphorylation)","04340(Hedgehog signaling pathway)","NA","NA","casein kinase 1 gamma 3 [Source:HGNC Symbol;Acc:HGNC:2456]",0,{"v":0.129552,"d":"0.13"},"-inf","-inf",1,1,"down","no"]
[123956,0,"chr20","+",44531909,44619037,"ENST00000372889",6,1489,"MSTRG.9757","PKIG","GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0005515(protein binding);GO:0004860(protein kinase inhibitor activity);GO:0004862(cAMP-dependent protein kinase inhibitor activity);GO:0006469(negative regulation of protein kinase activity);GO:0071901(negative regulation of protein serine/threonine kinase activity);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:2000480(negative regulation of cAMP-dependent protein kinase activity);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0007165(signal transduction);GO:0042308(negative regulation of protein import into nucleus)","NA","NA","NA","cAMP-dependent protein kinase inhibitor gamma [Source:HGNC Symbol;Acc:HGNC:9019]",{"v":0.307448,"d":"0.31"},{"v":1.180699,"d":"1.18"},{"v":0.260394901664184,"d":"0.26"},{"v":-1.94122689298829,"d":"-1.94"},1,1,"down","no"]
[97182,0,"chr19","-",12825479,12835428,"ENST00000589272",7,2076,"MSTRG.7855","RTBDN","GO:0016020(membrane);GO:0005886(plasma membrane);GO:0005576(extracellular region);GO:0005578(proteinaceous extracellular matrix);GO:0033165(interphotoreceptor matrix);GO:1902444(riboflavin binding);GO:0019897(extrinsic component of plasma membrane)","NA","NA","NA","retbindin [Source:HGNC Symbol;Acc:HGNC:30310]",0,0,1,0,1,1,"no","no"]
[41908,0,"chr12","-",52565782,52573816,"ENST00000549343",10,2858,"ENSG00000170484","KRT74","GO:0005198(structural molecule activity);GO:0005882(intermediate filament);GO:0045095(keratin filament);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0031424(keratinization);GO:0045104(intermediate filament cytoskeleton organization);GO:0070268(cornification);GO:1990254(keratin filament binding)","NA","NA","NA","keratin 74 [Source:HGNC Symbol;Acc:HGNC:28929]",0,{"v":0.015507,"d":"0.02"},"-inf","-inf",1,1,"down","no"]
[123572,0,"chr20","+",37400251,37402292,"ENST00000477475",3,584,"ENSG00000197122","SRC","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0005829(cytosol);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0005743(mitochondrial inner membrane);GO:0007155(cell adhesion);GO:0004713(protein tyrosine kinase activity);GO:0005886(plasma membrane);GO:0005739(mitochondrion);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0007049(cell cycle);GO:0004715(non-membrane spanning protein tyrosine kinase activity);GO:0007229(integrin-mediated signaling pathway);GO:0002376(immune system process);GO:0005764(lysosome);GO:0038096(Fc-gamma receptor signaling pathway involved in phagocytosis);GO:0050900(leukocyte migration);GO:0045087(innate immune response);GO:0020037(heme binding);GO:0045453(bone resorption);GO:0005654(nucleoplasm);GO:0045296(cadherin binding);GO:0070062(extracellular exosome);GO:0071902(positive regulation of protein serine/threonine kinase activity);GO:0042169(SH2 domain binding);GO:0002223(stimulatory C-type lectin receptor signaling pathway);GO:0016032(viral process);GO:0005770(late endosome);GO:0005102(receptor binding);GO:0051902(negative regulation of mitochondrial depolarization);GO:0043066(negative regulation of apoptotic process);GO:0044325(ion channel binding);GO:0007165(signal transduction);GO:0019899(enzyme binding);GO:0042127(regulation of cell proliferation);GO:0030168(platelet activation);GO:0007411(axon guidance);GO:0048013(ephrin receptor signaling pathway);GO:0046777(protein autophosphorylation);GO:0048010(vascular endothelial growth factor receptor signaling pathway);GO:0007179(transforming growth factor beta receptor signaling pathway);GO:0043154(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process);GO:2001243(negative regulation of intrinsic apoptotic signaling pathway);GO:0005070(SH3/SH2 adaptor activity);GO:0038128(ERBB2 signaling pathway);GO:0097110(scaffold protein binding);GO:0007417(central nervous system development);GO:0035556(intracellular signal transduction);GO:0051897(positive regulation of protein kinase B signaling);GO:0032463(negative regulation of protein homooligomerization);GO:0070851(growth factor receptor binding);GO:0007173(epidermal growth factor receptor signaling pathway);GO:0051219(phosphoprotein binding);GO:2001237(negative regulation of extrinsic apoptotic signaling pathway);GO:0010634(positive regulation of epithelial cell migration);GO:0050731(positive regulation of peptidyl-tyrosine phosphorylation);GO:0031295(T cell costimulation);GO:0019900(kinase binding);GO:0051895(negative regulation of focal adhesion assembly);GO:0070555(response to interleukin-1);GO:0016236(macroautophagy);GO:0033625(positive regulation of integrin activation);GO:0038083(peptidyl-tyrosine autophosphorylation);GO:0005901(caveola);GO:0031234(extrinsic component of cytoplasmic side of plasma membrane);GO:0035635(entry of bacterium into host cell);GO:2000641(regulation of early endosome to late endosome transport);GO:0051726(regulation of cell cycle);GO:0008022(protein C-terminus binding);GO:0005178(integrin binding);GO:0051974(negative regulation of telomerase activity);GO:0045124(regulation of bone resorption);GO:2000811(negative regulation of anoikis);GO:0018108(peptidyl-tyrosine phosphorylation);GO:0046875(ephrin receptor binding);GO:0007172(signal complex assembly);GO:0032211(negative regulation of telomere maintenance via telomerase);GO:0043114(regulation of vascular permeability);GO:2000394(positive regulation of lamellipodium morphogenesis);GO:0005080(protein kinase C binding);GO:0005158(insulin receptor binding);GO:0019901(protein kinase binding);GO:0019904(protein domain specific binding);GO:0030331(estrogen receptor binding);GO:0031625(ubiquitin protein ligase binding);GO:0032403(protein complex binding);GO:0050839(cell adhesion molecule binding);GO:0051427(hormone receptor binding);GO:0071253(connexin binding);GO:0008283(cell proliferation);GO:0009612(response to mechanical stimulus);GO:0009615(response to virus);GO:0010447(response to acidic pH);GO:0010628(positive regulation of gene expression);GO:0010632(regulation of epithelial cell migration);GO:0010641(positive regulation of platelet-derived growth factor receptor signaling pathway);GO:0010907(positive regulation of glucose metabolic process);GO:0010954(positive regulation of protein processing);GO:0014911(positive regulation of smooth muscle cell migration);GO:0016337(single organismal cell-cell adhesion);GO:0016477(cell migration);GO:0018105(peptidyl-serine phosphorylation);GO:0022407(regulation of cell-cell adhesion);GO:0030520(intracellular estrogen receptor signaling pathway);GO:0030900(forebrain development);GO:0031648(protein destabilization);GO:0031667(response to nutrient levels);GO:0031954(positive regulation of protein autophosphorylation);GO:0032148(activation of protein kinase B activity);GO:0032869(cellular response to insulin stimulus);GO:0033146(regulation of intracellular estrogen receptor signaling pathway);GO:0034332(adherens junction organization);GO:0034446(substrate adhesion-dependent cell spreading);GO:0034614(cellular response to reactive oxygen species);GO:0036035(osteoclast development);GO:0036120(cellular response to platelet-derived growth factor stimulus);GO:0042493(response to drug);GO:0042542(response to hydrogen peroxide);GO:0043065(positive regulation of apoptotic process);GO:0043149(stress fiber assembly);GO:0043393(regulation of protein binding);GO:0043406(positive regulation of MAP kinase activity);GO:0043552(positive regulation of phosphatidylinositol 3-kinase activity);GO:0045056(transcytosis);GO:0045737(positive regulation of cyclin-dependent protein serine/threonine kinase activity);GO:0045785(positive regulation of cell adhesion);GO:0045892(negative regulation of transcription, DNA-templated);GO:0045893(positive regulation of transcription, DNA-templated);GO:0046628(positive regulation of insulin receptor signaling pathway);GO:0048008(platelet-derived growth factor receptor signaling pathway);GO:0048011(neurotrophin TRK receptor signaling pathway);GO:0048477(oogenesis);GO:0050715(positive regulation of cytokine secretion);GO:0050847(progesterone receptor signaling pathway);GO:0051057(positive regulation of small GTPase mediated signal transduction);GO:0051222(positive regulation of protein transport);GO:0051385(response to mineralocorticoid);GO:0051602(response to electrical stimulus);GO:0060065(uterus development);GO:0060444(branching involved in mammary gland duct morphogenesis);GO:0060491(regulation of cell projection assembly);GO:0070374(positive regulation of ERK1 and ERK2 cascade);GO:0070542(response to fatty acid);GO:0071222(cellular response to lipopolysaccharide);GO:0071375(cellular response to peptide hormone stimulus);GO:0071393(cellular response to progesterone stimulus);GO:0071398(cellular response to fatty acid);GO:0071456(cellular response to hypoxia);GO:0071498(cellular response to fluid shear stress);GO:0071560(cellular response to transforming growth factor beta stimulus);GO:0071801(regulation of podosome assembly);GO:0071803(positive regulation of podosome assembly);GO:0086098(angiotensin-activated signaling pathway involved in heart process);GO:0090263(positive regulation of canonical Wnt signaling pathway);GO:1900182(positive regulation of protein localization to nucleus);GO:1902533(positive regulation of intracellular signal transduction);GO:2000573(positive regulation of DNA biosynthetic process);GO:2001286(regulation of caveolin-mediated endocytosis);GO:0002102(podosome);GO:0005884(actin filament);GO:0014069(postsynaptic density);GO:0032587(ruffle membrane);GO:0043005(neuron projection);GO:0048471(perinuclear region of cytoplasm)","04015(Rap1 signaling pathway);04012(ErbB signaling pathway);04370(VEGF signaling pathway);04144(Endocytosis);04137(Mitophagy - animal);04510(Focal adhesion);04520(Adherens junction);04530(Tight junction);04540(Gap junction);04810(Regulation of actin cytoskeleton);04611(Platelet activation);04062(Chemokine signaling pathway);04912(GnRH signaling pathway);04915(Estrogen signaling pathway);04917(Prolactin signaling pathway);04921(Oxytocin signaling pathway);04926(Relaxin signaling pathway);04919(Thyroid hormone signaling pathway);04727(GABAergic synapse);04750(Inflammatory mediator regulation of TRP channels);04360(Axon guidance);05205(Proteoglycans in cancer);05203(Viral carcinogenesis);05219(Bladder cancer);05418(Fluid shear stress and atherosclerosis);05120(Epithelial cell signaling in Helicobacter pylori infection);05131(Shigellosis);05152(Tuberculosis);05100(Bacterial invasion of epithelial cells);05161(Hepatitis B);05167(Kaposi's sarcoma-associated herpesvirus infection);01521(EGFR tyrosine kinase inhibitor resistance);01522(Endocrine resistance)","NA","NA","SRC proto-oncogene, non-receptor tyrosine kinase [Source:HGNC Symbol;Acc:HGNC:11283]",0,0,1,0,1,1,"no","no"]
[8845,0,"chr1","+",109616104,109626198,"ENST00000531734",5,572,"MSTRG.768","AMPD2","GO:0003876(AMP deaminase activity);GO:0032264(IMP salvage);GO:0046872(metal ion binding);GO:0016787(hydrolase activity);GO:0019239(deaminase activity);GO:0009168(purine ribonucleoside monophosphate biosynthetic process);GO:0005515(protein binding);GO:0009117(nucleotide metabolic process);GO:0005575(cellular_component);GO:0005829(cytosol);GO:0043101(purine-containing compound salvage);GO:0006188(IMP biosynthetic process);GO:0052652(cyclic purine nucleotide metabolic process);GO:0097009(energy homeostasis)","00230(Purine metabolism)","NA","NA","adenosine monophosphate deaminase 2 [Source:HGNC Symbol;Acc:HGNC:469]",{"v":0.18338,"d":"0.18"},{"v":0.172614,"d":"0.17"},{"v":1.06237037551995,"d":"1.06"},{"v":0.0872868224240263,"d":"0.09"},1,1,"up","no"]
[158122,0,"chr5","-",131954234,131994251,"ENST00000431707",21,2060,"ENSG00000164398","ACSL6","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0003824(catalytic activity);GO:0006629(lipid metabolic process);GO:0008152(metabolic process);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0006631(fatty acid metabolic process);GO:0005739(mitochondrion);GO:0042803(protein homodimerization activity);GO:0005886(plasma membrane);GO:0016874(ligase activity);GO:0005741(mitochondrial outer membrane);GO:0001676(long-chain fatty acid metabolic process);GO:0005777(peroxisome);GO:0005778(peroxisomal membrane);GO:0043231(intracellular membrane-bounded organelle);GO:0035338(long-chain fatty-acyl-CoA biosynthetic process);GO:0031090(organelle membrane);GO:0006637(acyl-CoA metabolic process);GO:0004467(long-chain fatty acid-CoA ligase activity);GO:0102391(decanoate--CoA ligase activity)","00061(Fatty acid biosynthesis);00071(Fatty acid degradation);04146(Peroxisome);04216(Ferroptosis);04920(Adipocytokine signaling pathway);03320(PPAR signaling pathway)","NA","NA","acyl-CoA synthetase long chain family member 6 [Source:HGNC Symbol;Acc:HGNC:16496]",0,{"v":1.29724,"d":"1.30"},"-inf","-inf",1,1,"down","no"]
[60736,0,"chr15","-",34148543,34154831,"ENST00000558473",4,575,"MSTRG.4882","KATNBL1","GO:0005515(protein binding);GO:0005730(nucleolus)","NA","NA","NA","katanin regulatory subunit B1 like 1 [Source:HGNC Symbol;Acc:HGNC:26199]",{"v":0.765648,"d":"0.77"},{"v":1.868006,"d":"1.87"},{"v":0.409874486484519,"d":"0.41"},{"v":-1.28674590576327,"d":"-1.29"},1,1,"down","no"]
[92488,0,"chr18","-",50795120,50825384,"ENST00000256425",8,5166,"ENSG00000134042","MRO","GO:0005634(nucleus);GO:0005730(nucleolus)","NA","NA","NA","maestro [Source:HGNC Symbol;Acc:HGNC:24121]",0,0,1,0,1,1,"no","no"]
[186185,0,"chr8","-",101871830,101872549,"ENST00000635554",1,720,"ENSG00000282989","AP001206.1","NA","NA","NA","NA","NA",0,0,1,0,1,1,"no","no"]
[80125,0,"chr17","-",17817526,17818345,"ENST00000487401",2,477,"ENSG00000072310","SREBF1","GO:0046983(protein dimerization activity);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0005794(Golgi apparatus);GO:0006629(lipid metabolic process);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0008202(steroid metabolic process);GO:0030522(intracellular receptor signaling pathway);GO:0000139(Golgi membrane);GO:0031410(cytoplasmic vesicle);GO:0008203(cholesterol metabolic process);GO:0005515(protein binding);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:1903146(regulation of mitophagy);GO:1903214(regulation of protein targeting to mitochondrion);GO:0005635(nuclear envelope);GO:0007623(circadian rhythm);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0045540(regulation of cholesterol biosynthetic process);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0000977(RNA polymerase II regulatory region sequence-specific DNA binding);GO:0031647(regulation of protein stability);GO:0012507(ER to Golgi transport vesicle membrane);GO:0010867(positive regulation of triglyceride biosynthetic process);GO:0008610(lipid biosynthetic process);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:0000982(transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0001077(transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0003682(chromatin binding);GO:0004879(RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding);GO:0019901(protein kinase binding);GO:0032403(protein complex binding);GO:0032810(sterol response element binding);GO:0043565(sequence-specific DNA binding);GO:0044212(transcription regulatory region DNA binding);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0003062(regulation of heart rate by chemical signal);GO:0007568(aging);GO:0008286(insulin receptor signaling pathway);GO:0009267(cellular response to starvation);GO:0009749(response to glucose);GO:0014070(response to organic cyclic compound);GO:0019217(regulation of fatty acid metabolic process);GO:0030324(lung development);GO:0031065(positive regulation of histone deacetylation);GO:0032094(response to food);GO:0032526(response to retinoic acid);GO:0032570(response to progesterone);GO:0032869(cellular response to insulin stimulus);GO:0033762(response to glucagon);GO:0033993(response to lipid);GO:0042493(response to drug);GO:0042789(mRNA transcription from RNA polymerase II promoter);GO:0043434(response to peptide hormone);GO:0045444(fat cell differentiation);GO:0045542(positive regulation of cholesterol biosynthetic process);GO:0045893(positive regulation of transcription, DNA-templated);GO:0046676(negative regulation of insulin secretion);GO:0050796(regulation of insulin secretion);GO:0051591(response to cAMP);GO:0070542(response to fatty acid);GO:0071398(cellular response to fatty acid);GO:0043231(intracellular membrane-bounded organelle);GO:0043234(protein complex)","04152(AMPK signaling pathway);04910(Insulin signaling pathway);04932(Non-alcoholic fatty liver disease (NAFLD));04931(Insulin resistance)","NA","NA","sterol regulatory element binding transcription factor 1 [Source:HGNC Symbol;Acc:HGNC:11289]",{"v":0.002661,"d":"0.00"},{"v":0.023277,"d":"0.02"},{"v":0.114318855522619,"d":"0.11"},{"v":-3.12886471648399,"d":"-3.13"},1,1,"down","no"]
[65322,0,"chr15","+",78347821,78348221,"ENST00000560753",1,401,"ENSG00000166426","CRABP1","GO:0006810(transport);GO:0005737(cytoplasm);GO:0005215(transporter activity);GO:0005515(protein binding);GO:0008289(lipid binding);GO:0005829(cytosol);GO:0001972(retinoic acid binding);GO:0034653(retinoic acid catabolic process);GO:0007165(signal transduction);GO:0007275(multicellular organism development);GO:0016918(retinal binding);GO:0019841(retinol binding);GO:0005501(retinoid binding)","NA","NA","NA","cellular retinoic acid binding protein 1 [Source:HGNC Symbol;Acc:HGNC:2338]",0,0,1,0,1,1,"no","no"]
[131329,0,"chr22","-",38667862,38670303,"ENST00000422408",2,1080,"MSTRG.10456","AL021707.2","NA","NA","NA","NA","NA",{"v":0.022933,"d":"0.02"},{"v":0.135772,"d":"0.14"},{"v":0.168908169578411,"d":"0.17"},{"v":-2.56568898625533,"d":"-2.57"},1,1,"down","no"]
[83126,0,"chr17","-",40475828,40501597,"ENST00000254051",13,4067,"ENSG00000131746","TNS4","GO:0005737(cytoplasm);GO:0003779(actin binding);GO:0005856(cytoskeleton);GO:0006915(apoptotic process);GO:0030054(cell junction);GO:0005925(focal adhesion);GO:0005515(protein binding);GO:0005829(cytosol);GO:0008104(protein localization)","NA","NA","NA","tensin 4 [Source:HGNC Symbol;Acc:HGNC:24352]",{"v":0.015016,"d":"0.02"},{"v":0.001202,"d":"0.00"},{"v":12.4925124792013,"d":"12.49"},{"v":3.64299175411969,"d":"3.64"},1,1,"up","no"]
[83569,0,"chr17","+",42533532,42534009,"ENST00000590314",1,478,"ENSG00000267185","AC067852.4","NA","NA","NA","NA","NA",0,0,1,0,1,1,"no","no"]
[74463,0,"chr16","-",67389846,67393491,"ENST00000562206",4,1410,"MSTRG.6006","TPPP3","GO:0005737(cytoplasm);GO:0005856(cytoskeleton);GO:0048471(perinuclear region of cytoplasm);GO:0015631(tubulin binding);GO:0001578(microtubule bundle formation);GO:0005874(microtubule);GO:0046785(microtubule polymerization);GO:0070062(extracellular exosome);GO:0097427(microtubule bundle)","NA","NA","NA","tubulin polymerization promoting protein family member 3 [Source:HGNC Symbol;Acc:HGNC:24162]",{"v":0.026821,"d":"0.03"},{"v":0.035545,"d":"0.04"},{"v":0.754564636376424,"d":"0.75"},{"v":-0.406283606878056,"d":"-0.41"},1,1,"down","no"]
[96700,0,"chr19","+",11322156,11324195,"ENST00000586051",2,906,"MSTRG.7822","AC011472.3","NA","NA","NA","NA","NA",0,0,1,0,1,1,"no","no"]
[5598,0,"chr1","+",46033868,46034420,"ENST00000492813",2,419,"ENSG00000086015","MAST2","GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0016740(transferase activity);GO:0000287(magnesium ion binding);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0045075(regulation of interleukin-12 biosynthetic process);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0046872(metal ion binding);GO:0005886(plasma membrane);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0035556(intracellular signal transduction);GO:0008017(microtubule binding);GO:0019902(phosphatase binding);GO:0018105(peptidyl-serine phosphorylation);GO:0048515(spermatid differentiation);GO:0007010(cytoskeleton organization);GO:0015630(microtubule cytoskeleton)","NA","NA","NA","microtubule associated serine/threonine kinase 2 [Source:HGNC Symbol;Acc:HGNC:19035]",0,0,1,0,1,1,"no","no"]
[191024,0,"chr9","-",71704800,71712443,"ENST00000537329",3,581,"MSTRG.14805","TMEM2","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016787(hydrolase activity);GO:0005886(plasma membrane);GO:0008152(metabolic process);GO:0016798(hydrolase activity, acting on glycosyl bonds);GO:0004415(hyalurononglucosaminidase activity);GO:0007275(multicellular organism development);GO:0005509(calcium ion binding);GO:0005887(integral component of plasma membrane);GO:0045296(cadherin binding);GO:0070062(extracellular exosome);GO:0001525(angiogenesis);GO:0030214(hyaluronan catabolic process);GO:1903670(regulation of sprouting angiogenesis)","NA","NA","NA","transmembrane protein 2 [Source:HGNC Symbol;Acc:HGNC:11869]",0,{"v":0.042564,"d":"0.04"},"-inf","-inf",1,1,"down","no"]
[177263,0,"chr7","+",102464956,102468377,"ENST00000463739",7,1062,"MSTRG.13848","LRWD1","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005730(nucleolus);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0016569(covalent chromatin modification);GO:0005694(chromosome);GO:0005856(cytoskeleton);GO:0006260(DNA replication);GO:0005815(microtubule organizing center);GO:0000775(chromosome, centromeric region);GO:0000776(kinetochore);GO:0000777(condensed chromosome kinetochore);GO:0006325(chromatin organization);GO:0000781(chromosome, telomeric region);GO:0005515(protein binding);GO:0003682(chromatin binding);GO:0035064(methylated histone binding);GO:0008327(methyl-CpG binding);GO:0005664(nuclear origin of replication recognition complex);GO:0006270(DNA replication initiation);GO:0071169(establishment of protein localization to chromatin);GO:0031933(telomeric heterochromatin);GO:0005721(pericentric heterochromatin)","NA","NA","NA","leucine rich repeats and WD repeat domain containing 1 [Source:HGNC Symbol;Acc:HGNC:21769]",{"v":0.284515,"d":"0.28"},0,"inf","inf",1,1,"up","no"]
[87269,0,"chr17","+",68126666,68129586,"ENST00000620266",1,2921,"MSTRG.7144","AC005332.9","NA","NA","NA","NA","NA",0,0,1,0,1,1,"no","no"]
[34329,0,"chr11","+",94706431,94799539,"ENST00000299004",5,653,"ENSG00000166025","AMOTL1","GO:0016055(Wnt signaling pathway);GO:0030054(cell junction);GO:0005923(bicellular tight junction);GO:0005515(protein binding);GO:0005829(cytosol);GO:0008180(COP9 signalosome);GO:0035329(hippo signaling);GO:0042802(identical protein binding);GO:0003365(establishment of cell polarity involved in ameboidal cell migration);GO:0043536(positive regulation of blood vessel endothelial cell migration);GO:0016324(apical plasma membrane);GO:0030027(lamellipodium);GO:0031410(cytoplasmic vesicle)","04530(Tight junction)","NA","NA","angiomotin like 1 [Source:HGNC Symbol;Acc:HGNC:17811]",0,0,1,0,1,1,"no","no"]
[33854,0,"chr11","-",85958755,85990258,"ENST00000530692",10,963,"MSTRG.2788","PICALM","GO:0048471(perinuclear region of cytoplasm);GO:0005634(nucleus);GO:0016020(membrane);GO:0043231(intracellular membrane-bounded organelle);GO:0006897(endocytosis);GO:0005794(Golgi apparatus);GO:0031410(cytoplasmic vesicle);GO:0005543(phospholipid binding);GO:0005545(1-phosphatidylinositol binding);GO:0030276(clathrin binding);GO:0048268(clathrin coat assembly);GO:0030136(clathrin-coated vesicle);GO:0005905(clathrin-coated pit);GO:0005515(protein binding);GO:0005829(cytosol);GO:0045296(cadherin binding);GO:0061024(membrane organization);GO:0016192(vesicle-mediated transport);GO:0045893(positive regulation of transcription, DNA-templated);GO:0006461(protein complex assembly);GO:0042734(presynaptic membrane);GO:0030132(clathrin coat of coated pit);GO:0006898(receptor-mediated endocytosis);GO:0030122(AP-2 adaptor complex);GO:0016197(endosomal transport);GO:0050750(low-density lipoprotein particle receptor binding);GO:0032050(clathrin heavy chain binding);GO:0032880(regulation of protein localization);GO:0048261(negative regulation of receptor-mediated endocytosis);GO:0045211(postsynaptic membrane);GO:1901216(positive regulation of neuron death);GO:1902004(positive regulation of amyloid-beta formation);GO:0097418(neurofibrillary tangle);GO:0045056(transcytosis);GO:0031623(receptor internalization);GO:0030100(regulation of endocytosis);GO:0072583(clathrin-dependent endocytosis);GO:0005769(early endosome);GO:0017137(Rab GTPase binding);GO:0035615(clathrin adaptor activity);GO:0008283(cell proliferation);GO:0010629(negative regulation of gene expression);GO:0016188(synaptic vesicle maturation);GO:0035459(cargo loading into vesicle);GO:0043547(positive regulation of GTPase activity);GO:0055072(iron ion homeostasis);GO:0098711(iron ion import across plasma membrane);GO:1902959(regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process);GO:1902961(positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process);GO:1902963(negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process);GO:0009986(cell surface);GO:0031982(vesicle);GO:0043025(neuronal cell body);GO:0070381(endosome to plasma membrane transport vesicle);GO:0007409(axonogenesis);GO:0007611(learning or memory);GO:0030097(hemopoiesis);GO:0048813(dendrite morphogenesis);GO:0090647(modulation of age-related behavioral decline);GO:1900223(positive regulation of amyloid-beta clearance);GO:0005622(intracellular)","NA","NA","NA","phosphatidylinositol binding clathrin assembly protein [Source:HGNC Symbol;Acc:HGNC:15514]",{"v":1.436365,"d":"1.44"},{"v":0.521302,"d":"0.52"},{"v":2.75534143356442,"d":"2.76"},{"v":1.46223110427343,"d":"1.46"},1,1,"up","no"]
[114243,0,"chr2","+",127645864,127652638,"ENST00000544369",4,2598,"ENSG00000144230","GPR17","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0004930(G-protein coupled receptor activity);GO:0007186(G-protein coupled receptor signaling pathway);GO:0005886(plasma membrane);GO:0004871(signal transducer activity);GO:0007165(signal transduction);GO:0070098(chemokine-mediated signaling pathway);GO:0005887(integral component of plasma membrane);GO:0035025(positive regulation of Rho protein signal transduction);GO:0051482(positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway);GO:0004950(chemokine receptor activity);GO:0002376(immune system process);GO:0002862(negative regulation of inflammatory response to antigenic stimulus)","NA","NA","NA","G protein-coupled receptor 17 [Source:HGNC Symbol;Acc:HGNC:4471]",0,0,1,0,1,1,"no","no"]
[42303,0,"chr12","-",53722155,53727452,"ENST00000546619",5,549,"MSTRG.3403","CALCOCO1","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0043231(intracellular membrane-bounded organelle);GO:0005829(cytosol);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0005515(protein binding);GO:0016055(Wnt signaling pathway);GO:0003713(transcription coactivator activity);GO:0045893(positive regulation of transcription, DNA-templated);GO:0001047(core promoter binding);GO:0008022(protein C-terminus binding);GO:0010628(positive regulation of gene expression);GO:0044212(transcription regulatory region DNA binding);GO:0003712(transcription cofactor activity);GO:0070016(armadillo repeat domain binding);GO:0008013(beta-catenin binding);GO:0043565(sequence-specific DNA binding);GO:0007165(signal transduction);GO:0030374(ligand-dependent nuclear receptor transcription coactivator activity);GO:0030518(intracellular steroid hormone receptor signaling pathway);GO:0003682(chromatin binding);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0000790(nuclear chromatin)","NA","NA","NA","calcium binding and coiled-coil domain 1 [Source:HGNC Symbol;Acc:HGNC:29306]",0,{"v":0.145498,"d":"0.15"},"-inf","-inf",1,1,"down","no"]
[169366,0,"chr6","-",134171365,134172739,"ENST00000525877",3,570,"MSTRG.13288","SGK1","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016607(nuclear speck);GO:0016020(membrane);GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0005829(cytosol);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005739(mitochondrion);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0006915(apoptotic process);GO:0035556(intracellular signal transduction);GO:0034220(ion transmembrane transport);GO:0004712(protein serine/threonine/tyrosine kinase activity);GO:0005246(calcium channel regulator activity);GO:0015459(potassium channel regulator activity);GO:0017080(sodium channel regulator activity);GO:0017081(chloride channel regulator activity);GO:0001558(regulation of cell growth);GO:0006814(sodium ion transport);GO:0006950(response to stress);GO:0006974(cellular response to DNA damage stimulus);GO:0007616(long-term memory);GO:0008217(regulation of blood pressure);GO:0018105(peptidyl-serine phosphorylation);GO:0030334(regulation of cell migration);GO:0032411(positive regulation of transporter activity);GO:0042127(regulation of cell proliferation);GO:0042981(regulation of apoptotic process);GO:0048812(neuron projection morphogenesis);GO:0050790(regulation of catalytic activity);GO:0051090(regulation of sequence-specific DNA binding transcription factor activity);GO:0060453(regulation of gastric acid secretion);GO:0070294(renal sodium ion absorption);GO:0035091(phosphatidylinositol binding)","04068(FoxO signaling pathway);04151(PI3K-Akt signaling pathway);04150(mTOR signaling pathway);04960(Aldosterone-regulated sodium reabsorption)","NA","NA","serum/glucocorticoid regulated kinase 1 [Source:HGNC Symbol;Acc:HGNC:10810]",{"v":0.196506,"d":"0.20"},{"v":0.018726,"d":"0.02"},{"v":10.4937520025633,"d":"10.49"},{"v":3.39145869536477,"d":"3.39"},1,1,"up","no"]
[197496,0,"chrX","-",53221705,53225198,"ENST00000349663",2,548,"MSTRG.15305","KDM5C","GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0016569(covalent chromatin modification);GO:0003677(DNA binding);GO:0008270(zinc ion binding);GO:0048511(rhythmic process);GO:0051213(dioxygenase activity);GO:0016706(oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors);GO:0045892(negative regulation of transcription, DNA-templated);GO:0032452(histone demethylase activity);GO:0032453(histone demethylase activity (H3-K4 specific));GO:0034720(histone H3-K4 demethylation);GO:0009636(response to toxic substance)","NA","NA","NA","lysine demethylase 5C [Source:HGNC Symbol;Acc:HGNC:11114]",{"v":0.578767,"d":"0.58"},{"v":0.265535,"d":"0.27"},{"v":2.17962603799876,"d":"2.18"},{"v":1.12408063068816,"d":"1.12"},1,1,"up","no"]
[48667,0,"chr12","-",132623753,132625951,"ENST00000541627",2,2105,"ENSG00000177084","POLE","GO:0005634(nucleus);GO:0003676(nucleic acid binding);GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0005654(nucleoplasm);GO:0016740(transferase activity);GO:0003677(DNA binding);GO:0005886(plasma membrane);GO:0006281(DNA repair);GO:0090305(nucleic acid phosphodiester bond hydrolysis);GO:0005515(protein binding);GO:0006974(cellular response to DNA damage stimulus);GO:0000166(nucleotide binding);GO:0008408(3'-5' exonuclease activity);GO:0006260(DNA replication);GO:0016779(nucleotidyltransferase activity);GO:0003887(DNA-directed DNA polymerase activity);GO:0051536(iron-sulfur cluster binding);GO:0051539(4 iron, 4 sulfur cluster binding);GO:0008622(epsilon DNA polymerase complex);GO:0003682(chromatin binding);GO:0008310(single-stranded DNA 3'-5' exodeoxyribonuclease activity);GO:0000082(G1/S transition of mitotic cell cycle);GO:0006270(DNA replication initiation);GO:0032201(telomere maintenance via semi-conservative replication);GO:0006272(leading strand elongation);GO:0000731(DNA synthesis involved in DNA repair);GO:0006287(base-excision repair, gap-filling);GO:0006297(nucleotide-excision repair, DNA gap filling);GO:0045004(DNA replication proofreading);GO:0048568(embryonic organ development);GO:0071897(DNA biosynthetic process)","00230(Purine metabolism);00240(Pyrimidine metabolism);03030(DNA replication);03410(Base excision repair);03420(Nucleotide excision repair);05166(HTLV-I infection)","NA","NA","DNA polymerase epsilon, catalytic subunit [Source:HGNC Symbol;Acc:HGNC:9177]",{"v":0.028148,"d":"0.03"},0,"inf","inf",1,1,"up","no"]
[27157,0,"chr11","-",18112626,18116078,"ENST00000533267",3,365,"ENSG00000166787","SAA3P","NA","NA","NA","NA","serum amyloid A3 pseudogene [Source:HGNC Symbol;Acc:HGNC:10515]",0,0,1,0,1,1,"no","no"]
[25141,0,"chr11","+",1006544,1008282,"ENST00000529427",2,345,"ENSG00000183020","AP2A2","GO:0006810(transport);GO:0016020(membrane);GO:0006886(intracellular protein transport);GO:0015031(protein transport);GO:0016192(vesicle-mediated transport);GO:0030117(membrane coat);GO:0008565(protein transporter activity);GO:0030131(clathrin adaptor complex);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0005905(clathrin-coated pit);GO:0008289(lipid binding);GO:0003674(molecular_function);GO:0005829(cytosol);GO:0006897(endocytosis);GO:0061024(membrane organization);GO:0060071(Wnt signaling pathway, planar cell polarity pathway);GO:0043312(neutrophil degranulation);GO:0007018(microtubule-based movement);GO:0019886(antigen processing and presentation of exogenous peptide antigen via MHC class II);GO:0030667(secretory granule membrane);GO:0048013(ephrin receptor signaling pathway);GO:0030666(endocytic vesicle membrane);GO:0031410(cytoplasmic vesicle);GO:0034383(low-density lipoprotein particle clearance);GO:0101003(ficolin-1-rich granule membrane);GO:0036020(endolysosome membrane);GO:0050690(regulation of defense response to virus by virus);GO:0030669(clathrin-coated endocytic vesicle membrane);GO:0019901(protein kinase binding);GO:0035615(clathrin adaptor activity);GO:0032802(low-density lipoprotein particle receptor catabolic process);GO:0072583(clathrin-dependent endocytosis);GO:0030122(AP-2 adaptor complex);GO:0019904(protein domain specific binding);GO:0097718(disordered domain specific binding)","04144(Endocytosis);04961(Endocrine and other factor-regulated calcium reabsorption);04721(Synaptic vesicle cycle);05016(Huntington's disease)","NA","NA","adaptor related protein complex 2 alpha 2 subunit [Source:HGNC Symbol;Acc:HGNC:562]",{"v":0.23932,"d":"0.24"},{"v":0.241242,"d":"0.24"},{"v":0.992032896427654,"d":"0.99"},{"v":-0.0115401328174128,"d":"-0.01"},1,1,"down","no"]
[69644,0,"chr16","-",11396404,11402264,"ENST00000612858",6,1046,"ENSG00000188897","AC099489.1","GO:0006869(lipid transport);GO:0005319(lipid transporter activity)","NA","NA","NA","NA",{"v":0.022726,"d":"0.02"},0,"inf","inf",1,1,"up","no"]
[9780,0,"chr1","+",119711936,119744213,"ENST00000641375",14,2196,"ENSG00000092621","PHGDH","GO:0010468(regulation of gene expression);GO:0043209(myelin sheath);GO:0031175(neuron projection development);GO:0004617(phosphoglycerate dehydrogenase activity);GO:0006541(glutamine metabolic process);GO:0006544(glycine metabolic process);GO:0006563(L-serine metabolic process);GO:0006566(threonine metabolic process);GO:0009448(gamma-aminobutyric acid metabolic process);GO:0019530(taurine metabolic process);GO:0021510(spinal cord development);GO:0021782(glial cell development);GO:0021915(neural tube development);GO:0022008(neurogenesis);GO:0070314(G1 to G0 transition);GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0008152(metabolic process);GO:0016616(oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor);GO:0051287(NAD binding);GO:0006564(L-serine biosynthetic process);GO:0008652(cellular amino acid biosynthetic process);GO:0030060(L-malate dehydrogenase activity);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0007420(brain development);GO:0009055(electron carrier activity)","00260(Glycine, serine and threonine metabolism)","NA","NA","phosphoglycerate dehydrogenase [Source:HGNC Symbol;Acc:HGNC:8923]",{"v":4.1E-5,"d":"0.00"},{"v":0.067376,"d":"0.07"},{"v":0.000608525290904773,"d":"0.00"},{"v":-10.682395155551,"d":"-10.68"},1,1,"down","no"]
[87873,0,"chr17","-",75135992,75153826,"ENST00000481647",5,576,"MSTRG.7192","JPT1","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005730(nucleolus);GO:0031965(nuclear membrane)","NA","NA","NA","Jupiter microtubule associated homolog 1 [Source:HGNC Symbol;Acc:HGNC:14569]",0,0,1,0,1,1,"no","no"]
[31011,0,"chr11","+",65084241,65085864,"ENST00000526289",3,980,"MSTRG.2535","ZFPL1","GO:0006810(transport);GO:0005634(nucleus);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005794(Golgi apparatus);GO:0046872(metal ion binding);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0008270(zinc ion binding);GO:0016192(vesicle-mediated transport)","NA","NA","NA","zinc finger protein like 1 [Source:HGNC Symbol;Acc:HGNC:12868]",0,0,1,0,1,1,"no","no"]
[136757,0,"chr3","-",50559222,50567680,"ENST00000430746",6,1520,"ENSG00000088543","C3orf18","GO:0016020(membrane);GO:0016021(integral component of membrane)","NA","NA","NA","chromosome 3 open reading frame 18 [Source:HGNC Symbol;Acc:HGNC:24837]",{"v":7.522E-3,"d":"0.01"},{"v":0.033038,"d":"0.03"},{"v":0.227677220170713,"d":"0.23"},{"v":-2.13493814241494,"d":"-2.13"},1,1,"down","no"]
[167132,0,"chr6","-",71302842,71328084,"ENST00000450998",5,525,"MSTRG.13118","AL589935.1","NA","NA","NA","NA","NA",{"v":0.002304,"d":"0.00"},0,"inf","inf",1,1,"up","no"]
[159818,0,"chr5","+",148307298,148308258,"ENST00000440731",2,581,"MSTRG.12439","PGBD4P3","NA","NA","NA","NA","piggyBac transposable element derived 4 pseudogene 3 [Source:HGNC Symbol;Acc:HGNC:44068]",{"v":0.080156,"d":"0.08"},0,"inf","inf",1,1,"up","no"]
[88455,0,"chr17","+",76547290,76553578,"ENST00000587063",2,553,"MSTRG.7251","PRCD","GO:0005737(cytoplasm);GO:0005794(Golgi apparatus);GO:0005783(endoplasmic reticulum);GO:0005576(extracellular region);GO:0050896(response to stimulus);GO:0007601(visual perception);GO:0001750(photoreceptor outer segment)","NA","NA","NA","photoreceptor disc component [Source:HGNC Symbol;Acc:HGNC:32528]",0,0,1,0,1,1,"no","no"]
[188570,0,"chr8","-",144978315,145002895,"ENST00000528392",4,599,"ENSG00000196922","ZNF252P","NA","NA","NA","NA","zinc finger protein 252, pseudogene [Source:HGNC Symbol;Acc:HGNC:13046]",{"v":0.137608,"d":"0.14"},{"v":0.506084,"d":"0.51"},{"v":0.27190743038705,"d":"0.27"},{"v":-1.87881251860347,"d":"-1.88"},1,1,"down","no"]
[93414,0,"chr18","-",74073371,74100068,"ENST00000580806",4,3187,"ENSG00000141665","FBXO15","GO:0000151(ubiquitin ligase complex);GO:0043161(proteasome-mediated ubiquitin-dependent protein catabolic process);GO:0005829(cytosol);GO:0000209(protein polyubiquitination);GO:0043687(post-translational protein modification);GO:0004842(ubiquitin-protein transferase activity)","NA","NA","NA","F-box protein 15 [Source:HGNC Symbol;Acc:HGNC:13617]",0,{"v":0.031937,"d":"0.03"},"-inf","-inf",1,1,"down","no"]
[140200,0,"chr3","+",128052426,128060211,"ENST00000481210",5,521,"MSTRG.11157","SEC61A1","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0015031(protein transport);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005515(protein binding);GO:0043022(ribosome binding);GO:0005829(cytosol);GO:0034341(response to interferon-gamma);GO:0039019(pronephric nephron development);GO:0005791(rough endoplasmic reticulum);GO:0045047(protein targeting to ER);GO:0030176(integral component of endoplasmic reticulum membrane);GO:0036498(IRE1-mediated unfolded protein response);GO:0006614(SRP-dependent cotranslational protein targeting to membrane);GO:0006620(posttranslational protein targeting to endoplasmic reticulum membrane);GO:0007029(endoplasmic reticulum organization);GO:0016049(cell growth)","03060(Protein export);04141(Protein processing in endoplasmic reticulum);04145(Phagosome);05110(Vibrio cholerae infection)","NA","NA","Sec61 translocon alpha 1 subunit [Source:HGNC Symbol;Acc:HGNC:18276]",{"v":0.558388,"d":"0.56"},{"v":0.181864,"d":"0.18"},{"v":3.07036026921216,"d":"3.07"},{"v":1.61840794813973,"d":"1.62"},1,1,"up","no"]
[71330,0,"chr16","+",28823095,28836919,"ENST00000564304",23,3514,"MSTRG.5784","ATXN2L","GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016607(nuclear speck);GO:0016020(membrane);GO:0005829(cytosol);GO:0005515(protein binding);GO:0045296(cadherin binding);GO:0010494(cytoplasmic stress granule);GO:0034063(stress granule assembly);GO:0010603(regulation of cytoplasmic mRNA processing body assembly);GO:0016021(integral component of membrane)","NA","NA","NA","ataxin 2 like [Source:HGNC Symbol;Acc:HGNC:31326]",{"v":0.492841,"d":"0.49"},0,"inf","inf",1,1,"up","no"]
[171104,0,"chr7","+",290170,291488,"ENST00000506382",3,702,"ENSG00000248767","AC187653.1","GO:0005634(nucleus);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0043565(sequence-specific DNA binding)","NA","NA","NA","NA",0,0,1,0,1,1,"no","no"]
[48938,0,"chr13","+",20026519,20086747,"ENST00000382870",19,3456,"ENSG00000121741","ZMYM2","GO:0005634(nucleus);GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0018108(peptidyl-tyrosine phosphorylation);GO:0005515(protein binding);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0005737(cytoplasm);GO:0008150(biological_process);GO:0005829(cytosol);GO:0000981(RNA polymerase II transcription factor activity, sequence-specific DNA binding);GO:0007275(multicellular organism development);GO:0003677(DNA binding);GO:0016605(PML body);GO:0004713(protein tyrosine kinase activity);GO:0007010(cytoskeleton organization);GO:0031624(ubiquitin conjugating enzyme binding);GO:0022604(regulation of cell morphogenesis)","NA","NA","NA","zinc finger MYM-type containing 2 [Source:HGNC Symbol;Acc:HGNC:12989]",0,0,1,0,1,1,"no","no"]
[50627,0,"chr13","-",52415525,52416161,"ENST00000462289",2,544,"MSTRG.4008","VPS36","GO:0006810(transport);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0015031(protein transport);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0005829(cytosol);GO:0043130(ubiquitin binding);GO:0032266(phosphatidylinositol-3-phosphate binding);GO:0008289(lipid binding);GO:0005515(protein binding);GO:0005768(endosome);GO:0031902(late endosome membrane);GO:0070062(extracellular exosome);GO:0016197(endosomal transport);GO:0016236(macroautophagy);GO:0036258(multivesicular body assembly);GO:0005770(late endosome);GO:0008022(protein C-terminus binding);GO:0043328(protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway);GO:0000814(ESCRT II complex);GO:0005764(lysosome)","04144(Endocytosis)","NA","NA","vacuolar protein sorting 36 homolog [Source:HGNC Symbol;Acc:HGNC:20312]",0,0,1,0,1,1,"no","no"]
[53561,0,"chr14","-",24180305,24188869,"ENST00000559588",29,3537,"MSTRG.4351","IPO4","GO:0006810(transport);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0006886(intracellular protein transport);GO:0015031(protein transport);GO:0000790(nuclear chromatin);GO:0008536(Ran GTPase binding);GO:0005643(nuclear pore);GO:0005515(protein binding);GO:0043234(protein complex);GO:0008139(nuclear localization sequence binding);GO:0008565(protein transporter activity);GO:0006607(NLS-bearing protein import into nucleus);GO:0000060(protein import into nucleus, translocation);GO:0031965(nuclear membrane);GO:0034399(nuclear periphery);GO:0006610(ribosomal protein import into nucleus);GO:0006335(DNA replication-dependent nucleosome assembly);GO:0006336(DNA replication-independent nucleosome assembly);GO:0005622(intracellular)","NA","NA","NA","importin 4 [Source:HGNC Symbol;Acc:HGNC:19426]",{"v":0.312132,"d":"0.31"},{"v":0.27375,"d":"0.27"},{"v":1.14020821917808,"d":"1.14"},{"v":0.189297306272019,"d":"0.19"},1,1,"up","no"]
[50321,0,"chr13","-",49376963,49413751,"ENST00000409082",4,468,"ENSG00000102547","CAB39L","GO:0005515(protein binding);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0007050(cell cycle arrest)","04152(AMPK signaling pathway);04150(mTOR signaling pathway)","NA","NA","calcium binding protein 39 like [Source:HGNC Symbol;Acc:HGNC:20290]",0,0,1,0,1,1,"no","no"]
[186879,0,"chr8","-",123348034,123348130,"ENST00000636914",1,97,"ENSG00000283172","hsa-mir-548d-1","NA","NA","NA","NA","hsa-mir-548d-1 [Source:miRBase;Acc:MI0003668]",{"v":0.0544,"d":"0.05"},0,"inf","inf",1,1,"up","no"]
[11782,0,"chr1","+",155610218,155614951,"ENST00000490743",13,2346,"MSTRG.1061","MSTO1","GO:0016020(membrane);GO:0003924(GTPase activity);GO:0005739(mitochondrion);GO:0005741(mitochondrial outer membrane);GO:0003674(molecular_function);GO:0005737(cytoplasm);GO:0007005(mitochondrion organization);GO:0048311(mitochondrion distribution)","NA","NA","NA","misato 1, mitochondrial distribution and morphology regulator [Source:HGNC Symbol;Acc:HGNC:29678]",0,{"v":0.574991,"d":"0.57"},"-inf","-inf",1,1,"down","no"]
[157692,0,"chr5","+",120531464,120686930,"ENST00000505123",4,1298,"ENSG00000184838","PRR16","GO:0005515(protein binding);GO:0045727(positive regulation of translation);GO:0045793(positive regulation of cell size)","NA","NA","NA","proline rich 16 [Source:HGNC Symbol;Acc:HGNC:29654]",0,0,1,0,1,1,"no","no"]
[70572,0,"chr16","+",21376648,21386064,"ENST00000548357",4,1007,"ENSG00000158482","SNX29P1","NA","NA","NA","NA","sorting nexin 29 pseudogene 1 [Source:HGNC Symbol;Acc:HGNC:31913]",{"v":0.670168,"d":"0.67"},{"v":0.25269,"d":"0.25"},{"v":2.65213502710831,"d":"2.65"},{"v":1.40715422868598,"d":"1.41"},1,1,"up","no"]
[164166,0,"chr6","-",30798654,30830659,"ENST00000419357",2,264,"ENSG00000214894","LINC00243","NA","NA","NA","NA","long intergenic non-protein coding RNA 243 [Source:HGNC Symbol;Acc:HGNC:30956]",{"v":0.013991,"d":"0.01"},{"v":0.2792,"d":"0.28"},{"v":0.0501110315186246,"d":"0.05"},{"v":-4.31872795431241,"d":"-4.32"},1,1,"down","no"]
[126186,0,"chr21","+",19244543,19246392,"ENST00000413933",1,1850,"ENSG00000226818","SLC6A6P1","NA","NA","NA","NA","solute carrier family 6 member 6 pseudogene 1 [Source:HGNC Symbol;Acc:HGNC:11053]",0,0,1,0,1,1,"no","no"]
[57281,0,"chr14","+",78614932,78988299,"ENST00000335750",12,2764,"ENSG00000021645","NRXN3","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0007269(neurotransmitter secretion);GO:0051965(positive regulation of synapse assembly);GO:0098793(presynapse);GO:0007268(chemical synaptic transmission);GO:0007416(synapse assembly);GO:0090129(positive regulation of synapse maturation);GO:0046872(metal ion binding);GO:0007155(cell adhesion);GO:0005886(plasma membrane);GO:0005887(integral component of plasma membrane);GO:0004872(receptor activity);GO:0007411(axon guidance);GO:0050839(cell adhesion molecule binding);GO:0007612(learning);GO:0035176(social behavior);GO:0097109(neuroligin family protein binding);GO:0007158(neuron cell-cell adhesion);GO:0030534(adult behavior);GO:0071625(vocalization behavior);GO:0065009(regulation of molecular function);GO:0005246(calcium channel regulator activity);GO:0043234(protein complex);GO:0001525(angiogenesis);GO:0007165(signal transduction);GO:0004888(transmembrane signaling receptor activity)","04514(Cell adhesion molecules (CAMs))","NA","NA","neurexin 3 [Source:HGNC Symbol;Acc:HGNC:8010]",0,0,1,0,1,1,"no","no"]
[25170,0,"chr11","-",1290915,1309597,"ENST00000527638",3,561,"MSTRG.2100","TOLLIP","GO:0005737(cytoplasm);GO:0016310(phosphorylation);GO:0005515(protein binding);GO:0004871(signal transducer activity);GO:0007165(signal transduction);GO:0006914(autophagy);GO:0002376(immune system process);GO:0045087(innate immune response);GO:0006954(inflammatory response);GO:0005576(extracellular region);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0043312(neutrophil degranulation);GO:0043130(ubiquitin binding);GO:0007267(cell-cell signaling);GO:0030855(epithelial cell differentiation);GO:0035580(specific granule lumen);GO:0035556(intracellular signal transduction);GO:0035578(azurophil granule lumen);GO:0019900(kinase binding);GO:0006511(ubiquitin-dependent protein catabolic process);GO:0035325(Toll-like receptor binding);GO:0045321(leukocyte activation);GO:0031624(ubiquitin conjugating enzyme binding);GO:0045323(interleukin-1 receptor complex);GO:0036010(protein localization to endosome);GO:0005150(interleukin-1, Type I receptor binding);GO:0031625(ubiquitin protein ligase binding);GO:0032183(SUMO binding);GO:0033235(positive regulation of protein sumoylation);GO:0016604(nuclear body);GO:0048471(perinuclear region of cytoplasm);GO:0045092(interleukin-18 receptor complex)","04620(Toll-like receptor signaling pathway)","NA","NA","toll interacting protein [Source:HGNC Symbol;Acc:HGNC:16476]",{"v":0.000235,"d":"0.00"},0,"inf","inf",1,1,"up","no"]
[76361,0,"chr16","+",84699995,84733061,"ENST00000569511",4,571,"MSTRG.6197","USP10","GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0016579(protein deubiquitination);GO:0016787(hydrolase activity);GO:0005515(protein binding);GO:0008233(peptidase activity);GO:0008234(cysteine-type peptidase activity);GO:0006508(proteolysis);GO:0006281(DNA repair);GO:0006974(cellular response to DNA damage stimulus);GO:0006511(ubiquitin-dependent protein catabolic process);GO:0036459(thiol-dependent ubiquitinyl hydrolase activity);GO:0006914(autophagy);GO:0005768(endosome);GO:0044325(ion channel binding);GO:0043234(protein complex);GO:0005769(early endosome);GO:0071347(cellular response to interleukin-1);GO:0004843(thiol-dependent ubiquitin-specific protease activity);GO:0010506(regulation of autophagy);GO:0043124(negative regulation of I-kappaB kinase/NF-kappaB signaling);GO:0019985(translesion synthesis);GO:0030330(DNA damage response, signal transduction by p53 class mediator);GO:0002039(p53 binding);GO:0004197(cysteine-type endopeptidase activity)","NA","NA","NA","ubiquitin specific peptidase 10 [Source:HGNC Symbol;Acc:HGNC:12608]",0,{"v":0.017176,"d":"0.02"},"-inf","-inf",1,1,"down","no"]
[33557,0,"chr11","+",78196797,78214419,"ENST00000530546",9,2986,"MSTRG.2757","USP35","GO:0016579(protein deubiquitination);GO:0006511(ubiquitin-dependent protein catabolic process);GO:0036459(thiol-dependent ubiquitinyl hydrolase activity);GO:0016787(hydrolase activity);GO:0008233(peptidase activity);GO:0008234(cysteine-type peptidase activity);GO:0006508(proteolysis);GO:0004843(thiol-dependent ubiquitin-specific protease activity)","NA","NA","NA","ubiquitin specific peptidase 35 [Source:HGNC Symbol;Acc:HGNC:20061]",0,0,1,0,1,1,"no","no"]
[10092,0,"chr1","+",145927236,145942081,"ENST00000595494",2,736,"MSTRG.864","LIX1L-AS1","NA","NA","NA","NA","LIX1L antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:41210]",{"v":0.150679,"d":"0.15"},{"v":0.060904,"d":"0.06"},{"v":2.47404111388415,"d":"2.47"},{"v":1.3068694753765,"d":"1.31"},1,1,"up","no"]
[201065,0,"chrX","-",153933660,153935015,"ENST00000478177",3,573,"MSTRG.15500","NAA10","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005730(nucleolus);GO:0005829(cytosol);GO:0016740(transferase activity);GO:0016746(transferase activity, transferring acyl groups);GO:0005515(protein binding);GO:0008080(N-acetyltransferase activity);GO:0043022(ribosome binding);GO:0006323(DNA packaging);GO:0006475(internal protein amino acid acetylation);GO:0005622(intracellular);GO:0004596(peptide alpha-N-acetyltransferase activity);GO:0016407(acetyltransferase activity);GO:1990189(peptide-serine-N-acetyltransferase activity);GO:1990190(peptide-glutamate-N-acetyltransferase activity);GO:0006473(protein acetylation);GO:0006474(N-terminal protein amino acid acetylation);GO:0017198(N-terminal peptidyl-serine acetylation);GO:0018002(N-terminal peptidyl-glutamic acid acetylation);GO:0022626(cytosolic ribosome);GO:0031415(NatA complex)","NA","NA","NA","N(alpha)-acetyltransferase 10, NatA catalytic subunit [Source:HGNC Symbol;Acc:HGNC:18704]",{"v":1.54E-4,"d":"0.00"},{"v":0.171764,"d":"0.17"},{"v":0.000896579027037097,"d":"0.00"},{"v":-10.1232816275883,"d":"-10.12"},1,1,"down","no"]
[193255,0,"chr9","+",124286440,124326405,"ENST00000423785",7,726,"MSTRG.14952","NEK6","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016607(nuclear speck);GO:0043231(intracellular membrane-bounded organelle);GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0051301(cell division);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0004871(signal transducer activity);GO:0007049(cell cycle);GO:0006915(apoptotic process);GO:0000287(magnesium ion binding);GO:0005815(microtubule organizing center);GO:0005874(microtubule);GO:0007165(signal transduction);GO:0000922(spindle pole);GO:0005813(centrosome);GO:0007059(chromosome segregation);GO:0019901(protein kinase binding);GO:0043234(protein complex);GO:0031625(ubiquitin protein ligase binding);GO:0043123(positive regulation of I-kappaB kinase/NF-kappaB signaling);GO:0007346(regulation of mitotic cell cycle);GO:2000772(regulation of cellular senescence);GO:0046777(protein autophosphorylation);GO:0000910(cytokinesis);GO:0019894(kinesin binding);GO:0031572(G2 DNA damage checkpoint);GO:0051225(spindle assembly);GO:0007077(mitotic nuclear envelope disassembly);GO:0001222(transcription corepressor binding);GO:0018105(peptidyl-serine phosphorylation);GO:0033613(activating transcription factor binding);GO:0030071(regulation of mitotic metaphase/anaphase transition)","NA","NA","NA","NIMA related kinase 6 [Source:HGNC Symbol;Acc:HGNC:7749]",{"v":0.022,"d":"0.02"},0,"inf","inf",1,1,"up","no"]
[93930,0,"chr19","+",572610,581543,"ENST00000613627",5,689,"MSTRG.7574","BSG","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0043231(intracellular membrane-bounded organelle);GO:0030246(carbohydrate binding);GO:0005739(mitochondrion);GO:0005886(plasma membrane);GO:0042470(melanosome);GO:0005925(focal adhesion);GO:0050900(leukocyte migration);GO:0005887(integral component of plasma membrane);GO:0005515(protein binding);GO:0045296(cadherin binding);GO:0070062(extracellular exosome);GO:0007166(cell surface receptor signaling pathway);GO:0006090(pyruvate metabolic process);GO:0000139(Golgi membrane);GO:0030198(extracellular matrix organization);GO:0022617(extracellular matrix disassembly);GO:0008028(monocarboxylic acid transmembrane transporter activity);GO:0005537(mannose binding);GO:0015718(monocarboxylic acid transport);GO:0072661(protein targeting to plasma membrane);GO:0007566(embryo implantation);GO:0042475(odontogenesis of dentin-containing tooth);GO:0043434(response to peptide hormone);GO:0046689(response to mercury ion);GO:0046697(decidualization);GO:0051591(response to cAMP);GO:0002080(acrosomal membrane);GO:0042383(sarcolemma);GO:0045121(membrane raft)","NA","NA","NA","basigin (Ok blood group) [Source:HGNC Symbol;Acc:HGNC:1116]",{"v":0.329462,"d":"0.33"},{"v":0.391287,"d":"0.39"},{"v":0.841995772923711,"d":"0.84"},{"v":-0.248115104347838,"d":"-0.25"},1,1,"down","no"]
[30898,0,"chr11","-",64804375,64806368,"ENST00000478548",3,1341,"MSTRG.2522","MEN1","GO:0005634(nucleus);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0016569(covalent chromatin modification);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0006281(DNA repair);GO:0006974(cellular response to DNA damage stimulus);GO:0018024(histone-lysine N-methyltransferase activity);GO:0003682(chromatin binding);GO:0034968(histone lysine methylation);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0044267(cellular protein metabolic process);GO:0008285(negative regulation of cell proliferation);GO:0043687(post-translational protein modification);GO:0032154(cleavage furrow);GO:0043234(protein complex);GO:0000784(nuclear chromosome, telomeric region);GO:0003690(double-stranded DNA binding);GO:0047485(protein N-terminus binding);GO:0000400(four-way junction DNA binding);GO:0000403(Y-form DNA binding);GO:0030674(protein binding, bridging);GO:0044212(transcription regulatory region DNA binding);GO:0070412(R-SMAD binding);GO:0000165(MAPK cascade);GO:0001933(negative regulation of protein phosphorylation);GO:0002076(osteoblast development);GO:0009411(response to UV);GO:0010332(response to gamma radiation);GO:0030511(positive regulation of transforming growth factor beta receptor signaling pathway);GO:0032092(positive regulation of protein binding);GO:0043433(negative regulation of sequence-specific DNA binding transcription factor activity);GO:0045668(negative regulation of osteoblast differentiation);GO:0045736(negative regulation of cyclin-dependent protein serine/threonine kinase activity);GO:0045786(negative regulation of cell cycle);GO:0045892(negative regulation of transcription, DNA-templated);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0046329(negative regulation of JNK cascade);GO:0051974(negative regulation of telomerase activity);GO:1904837(beta-catenin-TCF complex assembly);GO:0000785(chromatin);GO:0000790(nuclear chromatin);GO:0005788(endoplasmic reticulum lumen);GO:0016363(nuclear matrix);GO:0035097(histone methyltransferase complex);GO:0000278(mitotic cell cycle);GO:0003309(type B pancreatic cell differentiation);GO:0007420(brain development);GO:0010812(negative regulation of cell-substrate adhesion);GO:0032925(regulation of activin receptor signaling pathway);GO:0046697(decidualization);GO:0050680(negative regulation of epithelial cell proliferation);GO:0061469(regulation of type B pancreatic cell proliferation);GO:0071333(cellular response to glucose stimulus);GO:0071375(cellular response to peptide hormone stimulus);GO:0071559(response to transforming growth factor beta);GO:1902807(negative regulation of cell cycle G1/S phase transition)","05202(Transcriptional misregulation in cancers)","NA","NA","menin 1 [Source:HGNC Symbol;Acc:HGNC:7010]",{"v":0.045019,"d":"0.05"},{"v":0.137488,"d":"0.14"},{"v":0.327439485627837,"d":"0.33"},{"v":-1.61069978931046,"d":"-1.61"},1,1,"down","no"]
[38267,0,"chr12","-",7091156,7092493,"ENST00000536092",2,632,"MSTRG.3087","C1R","GO:0016787(hydrolase activity);GO:0005509(calcium ion binding);GO:0005515(protein binding);GO:0008233(peptidase activity);GO:0006508(proteolysis);GO:0005576(extracellular region);GO:0004252(serine-type endopeptidase activity);GO:0008236(serine-type peptidase activity);GO:0002376(immune system process);GO:0045087(innate immune response);GO:0006956(complement activation);GO:0006958(complement activation, classical pathway);GO:0030449(regulation of complement activation);GO:0070062(extracellular exosome);GO:0072562(blood microparticle);GO:0006955(immune response);GO:0005615(extracellular space);GO:0031638(zymogen activation)","04145(Phagosome);04610(Complement and coagulation cascades);05322(Systemic lupus erythematosus);05133(Pertussis);05150(Staphylococcus aureus infection)","NA","NA","complement C1r [Source:HGNC Symbol;Acc:HGNC:1246]",{"v":0.030614,"d":"0.03"},{"v":0.066883,"d":"0.07"},{"v":0.457724683402359,"d":"0.46"},{"v":-1.12744800163355,"d":"-1.13"},1,1,"down","no"]
[53679,0,"chr14","-",24241696,24242558,"ENST00000557921",2,499,"MSTRG.4357","TINF2","GO:0050680(negative regulation of epithelial cell proliferation);GO:0005634(nucleus);GO:0005694(chromosome);GO:0005515(protein binding);GO:0016604(nuclear body);GO:0000781(chromosome, telomeric region);GO:0005654(nucleoplasm);GO:0000784(nuclear chromosome, telomeric region);GO:0016363(nuclear matrix);GO:0000783(nuclear telomere cap complex);GO:0042162(telomeric DNA binding);GO:0070198(protein localization to chromosome, telomeric region);GO:0032211(negative regulation of telomere maintenance via telomerase);GO:0016233(telomere capping);GO:0070187(shelterin complex);GO:0032202(telomere assembly);GO:0010836(negative regulation of protein ADP-ribosylation);GO:1904356(regulation of telomere maintenance via telomere lengthening);GO:0010370(perinucleolar chromocenter)","NA","NA","NA","TERF1 interacting nuclear factor 2 [Source:HGNC Symbol;Acc:HGNC:11824]",{"v":0.16669,"d":"0.17"},{"v":0.313934,"d":"0.31"},{"v":0.53097147808138,"d":"0.53"},{"v":-0.913293728275455,"d":"-0.91"},1,1,"down","no"]
[104228,0,"chr19","-",49908105,49929443,"ENST00000597029",3,2053,"ENSG00000213024","NUP62","GO:0006810(transport);GO:0051028(mRNA transport);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0015031(protein transport);GO:0043231(intracellular membrane-bounded organelle);GO:0006351(transcription, DNA-templated);GO:0031965(nuclear membrane);GO:0017056(structural constituent of nuclear pore);GO:0051169(nuclear transport);GO:0005643(nuclear pore);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0045893(positive regulation of transcription, DNA-templated);GO:0000922(spindle pole);GO:0005813(centrosome);GO:0005815(microtubule organizing center);GO:0042169(SH2 domain binding);GO:0008285(negative regulation of cell proliferation);GO:0075733(intracellular transport of virus);GO:0043657(host cell);GO:0003682(chromatin binding);GO:0016032(viral process);GO:0007098(centrosome cycle);GO:0043123(positive regulation of I-kappaB kinase/NF-kappaB signaling);GO:0009755(hormone-mediated signaling pathway);GO:0098534(centriole assembly);GO:0043130(ubiquitin binding);GO:0043066(negative regulation of apoptotic process);GO:0046601(positive regulation of centriole replication);GO:0008219(cell death);GO:0009966(regulation of signal transduction);GO:0005635(nuclear envelope);GO:0045840(positive regulation of mitotic nuclear division);GO:0030529(intracellular ribonucleoprotein complex);GO:0006406(mRNA export from nucleus);GO:0016925(protein sumoylation);GO:0006606(protein import into nucleus);GO:0060964(regulation of gene silencing by miRNA);GO:0006110(regulation of glycolytic process);GO:0006409(tRNA export from nucleus);GO:0007077(mitotic nuclear envelope disassembly);GO:0019083(viral transcription);GO:1900034(regulation of cellular response to heat);GO:0007080(mitotic metaphase plate congression);GO:0030159(receptor signaling complex scaffold activity);GO:0072686(mitotic spindle);GO:0090543(Flemming body);GO:0046966(thyroid hormone receptor binding);GO:0007166(cell surface receptor signaling pathway);GO:0045742(positive regulation of epidermal growth factor receptor signaling pathway);GO:0043069(negative regulation of programmed cell death);GO:0044613(nuclear pore central transport channel);GO:0005487(nucleocytoplasmic transporter activity);GO:0005543(phospholipid binding);GO:0007100(mitotic centrosome separation);GO:0046578(regulation of Ras protein signal transduction);GO:0060236(regulation of mitotic spindle organization);GO:0071426(ribonucleoprotein complex export from nucleus);GO:1903438(positive regulation of mitotic cytokinetic process);GO:1904781(positive regulation of protein localization to centrosome);GO:0019894(kinesin binding);GO:0030544(Hsp70 protein binding);GO:0051425(PTB domain binding);GO:0051879(Hsp90 protein binding);GO:0000278(mitotic cell cycle);GO:0007283(spermatogenesis);GO:0007569(cell aging);GO:0042059(negative regulation of epidermal growth factor receptor signaling pathway);GO:0042306(regulation of protein import into nucleus);GO:0043407(negative regulation of MAP kinase activity);GO:0046580(negative regulation of Ras protein signal transduction);GO:0070208(protein heterotrimerization);GO:0005642(annulate lamellae);GO:0043234(protein complex)","03013(RNA transport)","K14306","NA","nucleoporin 62 [Source:HGNC Symbol;Acc:HGNC:8066]",{"v":1.70172,"d":"1.70"},{"v":0.111275,"d":"0.11"},{"v":15.2929229386655,"d":"15.29"},{"v":3.93479227046133,"d":"3.93"},1,1,"up","no"]
[158239,0,"chr5","+",132673986,132682676,"ENST00000231449",4,616,"ENSG00000113520","IL4","GO:0008083(growth factor activity);GO:0005576(extracellular region);GO:0005515(protein binding);GO:0006955(immune response);GO:0005125(cytokine activity);GO:0005615(extracellular space);GO:0045893(positive regulation of transcription, DNA-templated);GO:0008203(cholesterol metabolic process);GO:0005126(cytokine receptor binding);GO:0030890(positive regulation of B cell proliferation);GO:0045582(positive regulation of T cell differentiation);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0042102(positive regulation of T cell proliferation);GO:0005136(interleukin-4 receptor binding);GO:0001774(microglial cell activation);GO:0001934(positive regulation of protein phosphorylation);GO:0002227(innate immune response in mucosa);GO:0002230(positive regulation of defense response to virus by host);GO:0002296(T-helper 1 cell lineage commitment);GO:0002639(positive regulation of immunoglobulin production);GO:0002674(negative regulation of acute inflammatory response);GO:0002677(negative regulation of chronic inflammatory response);GO:0007565(female pregnancy);GO:0007584(response to nutrient);GO:0008284(positive regulation of cell proliferation);GO:0010155(regulation of proton transport);GO:0014070(response to organic cyclic compound);GO:0031296(B cell costimulation);GO:0032733(positive regulation of interleukin-10 production);GO:0034097(response to cytokine);GO:0042104(positive regulation of activated T cell proliferation);GO:0042113(B cell activation);GO:0042493(response to drug);GO:0042531(positive regulation of tyrosine phosphorylation of STAT protein);GO:0042832(defense response to protozoan);GO:0043031(negative regulation of macrophage activation);GO:0043306(positive regulation of mast cell degranulation);GO:0045019(negative regulation of nitric oxide biosynthetic process);GO:0045064(T-helper 2 cell differentiation);GO:0045080(positive regulation of chemokine biosynthetic process);GO:0045348(positive regulation of MHC class II biosynthetic process);GO:0045471(response to ethanol);GO:0045671(negative regulation of osteoclast differentiation);GO:0048295(positive regulation of isotype switching to IgE isotypes);GO:0048304(positive regulation of isotype switching to IgG isotypes);GO:0050727(regulation of inflammatory response);GO:0050731(positive regulation of peptidyl-tyrosine phosphorylation);GO:0050776(regulation of immune response);GO:0050868(negative regulation of T cell activation);GO:0050871(positive regulation of B cell activation);GO:0051091(positive regulation of sequence-specific DNA binding transcription factor activity);GO:0060041(retina development in camera-type eye);GO:0070351(negative regulation of white fat cell proliferation);GO:0071288(cellular response to mercury ion);GO:0071677(positive regulation of mononuclear cell migration);GO:0097192(extrinsic apoptotic signaling pathway in absence of ligand);GO:1901741(positive regulation of myoblast fusion);GO:1903428(positive regulation of reactive oxygen species biosynthetic process);GO:2000320(negative regulation of T-helper 17 cell differentiation);GO:2000424(positive regulation of eosinophil chemotaxis);GO:2001237(negative regulation of extrinsic apoptotic signaling pathway);GO:0009897(external side of plasma membrane);GO:0043066(negative regulation of apoptotic process);GO:0006935(chemotaxis);GO:0045892(negative regulation of transcription, DNA-templated);GO:0043011(myeloid dendritic cell differentiation);GO:0006968(cellular defense response);GO:0042325(regulation of phosphorylation);GO:0097028(dendritic cell differentiation);GO:0010633(negative regulation of epithelial cell migration);GO:0030183(B cell differentiation);GO:0032736(positive regulation of interleukin-13 production);GO:0035745(T-helper 2 cell cytokine production);GO:0042092(type 2 immune response);GO:0045189(connective tissue growth factor biosynthetic process);GO:0045191(regulation of isotype switching);GO:1903660(negative regulation of complement-dependent cytotoxicity);GO:2000352(negative regulation of endothelial cell apoptotic process)","04630(Jak-STAT signaling pathway);04151(PI3K-Akt signaling pathway);04060(Cytokine-cytokine receptor interaction);04640(Hematopoietic cell lineage);04660(T cell receptor signaling pathway);04658(Th1 and Th2 cell differentiation);04659(Th17 cell differentiation);04657(IL-17 signaling pathway);04664(Fc epsilon RI signaling pathway);04672(Intestinal immune network for IgA production);05200(Pathways in cancer);05310(Asthma);05320(Autoimmune thyroid disease);05321(Inflammatiory bowel disease (IBD));05330(Allograft rejection);05162(Measles);05140(Leishmaniasis)","K05430","NA","interleukin 4 [Source:HGNC Symbol;Acc:HGNC:6014]",0,{"v":0.389197,"d":"0.39"},"-inf","-inf",1,1,"down","no"]
[148801,0,"chr4","-",83266697,83284765,"ENST00000311461",7,1464,"ENSG00000173085","COQ2","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016765(transferase activity, transferring alkyl or aryl (other than methyl) groups);GO:0004659(prenyltransferase activity);GO:0016740(transferase activity);GO:0005743(mitochondrial inner membrane);GO:0005739(mitochondrion);GO:0006744(ubiquinone biosynthetic process);GO:0031305(integral component of mitochondrial inner membrane);GO:0002083(4-hydroxybenzoate decaprenyltransferase activity);GO:0047293(4-hydroxybenzoate nonaprenyltransferase activity);GO:0008299(isoprenoid biosynthetic process);GO:0006071(glycerol metabolic process)","00130(Ubiquinone and other terpenoid-quinone biosynthesis)","NA","NA","coenzyme Q2, polyprenyltransferase [Source:HGNC Symbol;Acc:HGNC:25223]",0,{"v":0.268772,"d":"0.27"},"-inf","-inf",1,1,"down","no"]
[160384,0,"chr5","-",154824484,154859252,"ENST00000520968",6,558,"MSTRG.12493","FAXDC2","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0005506(iron ion binding);GO:0008610(lipid biosynthetic process);GO:0005789(endoplasmic reticulum membrane);GO:0006629(lipid metabolic process)","NA","NA","NA","fatty acid hydroxylase domain containing 2 [Source:HGNC Symbol;Acc:HGNC:1334]",{"v":0.138873,"d":"0.14"},{"v":0.00151,"d":"0.00"},{"v":91.9688741721854,"d":"91.97"},{"v":6.52307377480285,"d":"6.52"},1,1,"up","no"]
[26403,0,"chr11","-",8730871,8835708,"ENST00000530959",5,751,"MSTRG.2230","ST5","GO:0043547(positive regulation of GTPase activity);GO:0005085(guanyl-nucleotide exchange factor activity);GO:0017112(Rab guanyl-nucleotide exchange factor activity)","NA","NA","NA","suppression of tumorigenicity 5 [Source:HGNC Symbol;Acc:HGNC:11350]",0,0,1,0,1,1,"no","no"]
[129072,0,"chr22","-",21923125,21926062,"ENST00000496143",3,544,"MSTRG.10224","PPM1F","GO:0046872(metal ion binding);GO:0016787(hydrolase activity);GO:0003824(catalytic activity);GO:0006470(protein dephosphorylation);GO:0005829(cytosol);GO:0004721(phosphoprotein phosphatase activity);GO:0005515(protein binding);GO:0006915(apoptotic process);GO:0004722(protein serine/threonine phosphatase activity);GO:0043169(cation binding);GO:0010628(positive regulation of gene expression);GO:0043234(protein complex);GO:0045892(negative regulation of transcription, DNA-templated);GO:0035690(cellular response to drug);GO:0043280(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process);GO:0097193(intrinsic apoptotic signaling pathway);GO:0006469(negative regulation of protein kinase activity);GO:0051496(positive regulation of stress fiber assembly);GO:0035970(peptidyl-threonine dephosphorylation);GO:0010634(positive regulation of epithelial cell migration);GO:0045927(positive regulation of growth);GO:0016791(phosphatase activity);GO:0010811(positive regulation of cell-substrate adhesion);GO:0050921(positive regulation of chemotaxis);GO:0051894(positive regulation of focal adhesion assembly);GO:0044387(negative regulation of protein kinase activity by regulation of protein phosphorylation);GO:0033137(negative regulation of peptidyl-serine phosphorylation);GO:0033192(calmodulin-dependent protein phosphatase activity);GO:0016576(histone dephosphorylation);GO:0048471(perinuclear region of cytoplasm)","NA","NA","NA","protein phosphatase, Mg2+/Mn2+ dependent 1F [Source:HGNC Symbol;Acc:HGNC:19388]",{"v":0.481113,"d":"0.48"},{"v":0.009913,"d":"0.01"},{"v":48.5335418137799,"d":"48.53"},{"v":5.6009102418373,"d":"5.60"},1,1,"up","no"]
[172538,0,"chr7","+",26364325,26372944,"ENST00000409838",4,944,"MSTRG.13529","SNX10","GO:0035091(phosphatidylinositol binding);GO:0006810(transport);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0015031(protein transport);GO:0005783(endoplasmic reticulum);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0005813(centrosome);GO:0005815(microtubule organizing center);GO:0008289(lipid binding);GO:0005768(endosome);GO:0060271(cilium assembly);GO:0030030(cell projection organization);GO:0010008(endosome membrane);GO:0030316(osteoclast differentiation);GO:0006897(endocytosis);GO:0007032(endosome organization);GO:0051117(ATPase binding);GO:0005545(1-phosphatidylinositol binding);GO:0031313(extrinsic component of endosome membrane);GO:0071539(protein localization to centrosome);GO:0061512(protein localization to cilium);GO:1990830(cellular response to leukemia inhibitory factor)","NA","NA","NA","sorting nexin 10 [Source:HGNC Symbol;Acc:HGNC:14974]",{"v":0.074388,"d":"0.07"},0,"inf","inf",1,1,"up","no"]
[84927,0,"chr17","+",47970534,47981772,"ENST00000536708",14,1975,"MSTRG.6978","CDK5RAP3","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005730(nucleolus);GO:0005829(cytosol);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0005874(microtubule);GO:0005813(centrosome);GO:0005815(microtubule organizing center);GO:0012505(endomembrane system);GO:0019901(protein kinase binding);GO:0008283(cell proliferation);GO:0032088(negative regulation of NF-kappaB transcription factor activity);GO:0031398(positive regulation of protein ubiquitination);GO:0043234(protein complex);GO:0001933(negative regulation of protein phosphorylation);GO:0007095(mitotic G2 DNA damage checkpoint);GO:0007420(brain development);GO:0051019(mitogen-activated protein kinase binding);GO:0030332(cyclin binding);GO:0051059(NF-kappaB binding);GO:0043407(negative regulation of MAP kinase activity);GO:0071901(negative regulation of protein serine/threonine kinase activity);GO:0071569(protein ufmylation);GO:0030968(endoplasmic reticulum unfolded protein response);GO:0010921(regulation of phosphatase activity);GO:1900182(positive regulation of protein localization to nucleus);GO:0044387(negative regulation of protein kinase activity by regulation of protein phosphorylation);GO:0000079(regulation of cyclin-dependent protein serine/threonine kinase activity);GO:0097371(MDM2/MDM4 family protein binding);GO:0045664(regulation of neuron differentiation);GO:0030262(apoptotic nuclear changes);GO:1903363(negative regulation of cellular protein catabolic process);GO:1901798(positive regulation of signal transduction by p53 class mediator);GO:0044389(ubiquitin-like protein ligase binding);GO:0044818(mitotic G2/M transition checkpoint);GO:0045944(positive regulation of transcription from RNA polymerase II promoter)","NA","NA","NA","CDK5 regulatory subunit associated protein 3 [Source:HGNC Symbol;Acc:HGNC:18673]",{"v":1.73E-4,"d":"0.00"},{"v":0.234461,"d":"0.23"},{"v":0.00073786258695476,"d":"0.00"},{"v":-10.4043602130978,"d":"-10.40"},1,1,"down","no"]
[124534,0,"chr20","+",49318535,49371908,"ENST00000637091",4,1629,"MSTRG.9816","AL035685.1","NA","NA","NA","NA","NA",{"v":0.273809,"d":"0.27"},0,"inf","inf",1,1,"up","no"]
[99852,0,"chr19","+",34677707,34683147,"ENST00000510002",3,538,"ENSG00000089335","ZNF302","GO:0003676(nucleic acid binding);GO:0006355(regulation of transcription, DNA-templated);GO:0005622(intracellular);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0003700(transcription factor activity, sequence-specific DNA binding)","NA","NA","NA","zinc finger protein 302 [Source:HGNC Symbol;Acc:HGNC:13848]",{"v":0.372975,"d":"0.37"},{"v":0.279351,"d":"0.28"},{"v":1.33514825434668,"d":"1.34"},{"v":0.416999947107893,"d":"0.42"},1,1,"up","no"]
[146777,0,"chr4","+",39182548,39219133,"ENST00000506503",14,2513,"ENSG00000157796","WDR19","GO:0005737(cytoplasm);GO:0005654(nucleoplasm);GO:0031514(motile cilium);GO:0005856(cytoskeleton);GO:0042995(cell projection);GO:0035735(intraciliary transport involved in cilium assembly);GO:0005929(cilium);GO:0097542(ciliary tip);GO:0030030(cell projection organization);GO:0060271(cilium assembly);GO:0001750(photoreceptor outer segment);GO:0032391(photoreceptor connecting cilium);GO:0030991(intraciliary transport particle A);GO:0097730(non-motile cilium);GO:0000902(cell morphogenesis);GO:0001701(in utero embryonic development);GO:0007224(smoothened signaling pathway);GO:0008406(gonad development);GO:0030326(embryonic limb morphogenesis);GO:0031076(embryonic camera-type eye development);GO:0035721(intraciliary retrograde transport);GO:0042471(ear morphogenesis);GO:0048701(embryonic cranial skeleton morphogenesis);GO:0050877(neurological system process);GO:0055123(digestive system development);GO:0060830(ciliary receptor clustering involved in smoothened signaling pathway);GO:0060831(smoothened signaling pathway involved in dorsal/ventral neural tube patterning);GO:0061055(myotome development)","NA","NA","NA","WD repeat domain 19 [Source:HGNC Symbol;Acc:HGNC:18340]",{"v":0.010289,"d":"0.01"},{"v":0.020251,"d":"0.02"},{"v":0.508073675374056,"d":"0.51"},{"v":-0.976890378618626,"d":"-0.98"},1,1,"down","no"]
[87002,0,"chr17","-",64502585,64503823,"ENST00000577787",4,838,"MSTRG.7113","DDX5","GO:0030509(BMP signaling pathway);GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0006397(mRNA processing);GO:0008380(RNA splicing);GO:0005634(nucleus);GO:0016020(membrane);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0016787(hydrolase activity);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0004386(helicase activity);GO:0005515(protein binding);GO:0005681(spliceosomal complex);GO:0048511(rhythmic process);GO:0003713(transcription coactivator activity);GO:0005730(nucleolus);GO:0005737(cytoplasm);GO:0003724(RNA helicase activity);GO:0000956(nuclear-transcribed mRNA catabolic process);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0005654(nucleoplasm);GO:0070062(extracellular exosome);GO:0004004(ATP-dependent RNA helicase activity);GO:0010501(RNA secondary structure unwinding);GO:0030331(estrogen receptor binding);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0031012(extracellular matrix);GO:0043021(ribonucleoprotein complex binding);GO:0000398(mRNA splicing, via spliceosome);GO:0070412(R-SMAD binding);GO:0000381(regulation of alternative mRNA splicing, via spliceosome);GO:0003730(mRNA 3'-UTR binding);GO:0030521(androgen receptor signaling pathway);GO:0030520(intracellular estrogen receptor signaling pathway);GO:0033148(positive regulation of intracellular estrogen receptor signaling pathway);GO:0030529(intracellular ribonucleoprotein complex);GO:0046332(SMAD binding);GO:0071141(SMAD protein complex);GO:0016049(cell growth);GO:0072332(intrinsic apoptotic signaling pathway by p53 class mediator);GO:0071013(catalytic step 2 spliceosome);GO:0050681(androgen receptor binding);GO:0043517(positive regulation of DNA damage response, signal transduction by p53 class mediator);GO:1990841(promoter-specific chromatin binding);GO:0000380(alternative mRNA splicing, via spliceosome);GO:0036002(pre-mRNA binding);GO:0001837(epithelial to mesenchymal transition);GO:1903800(positive regulation of production of miRNAs involved in gene silencing by miRNA);GO:0045445(myoblast differentiation);GO:0070878(primary miRNA binding);GO:0045667(regulation of osteoblast differentiation);GO:0005516(calmodulin binding);GO:0019899(enzyme binding);GO:0035500(MH2 domain binding);GO:0048306(calcium-dependent protein binding);GO:0009299(mRNA transcription);GO:0045069(regulation of viral genome replication);GO:0060765(regulation of androgen receptor signaling pathway);GO:0061614(pri-miRNA transcription from RNA polymerase II promoter);GO:2001014(regulation of skeletal muscle cell differentiation)","03040(Spliceosome);05202(Transcriptional misregulation in cancers);05205(Proteoglycans in cancer)","NA","NA","DEAD-box helicase 5 [Source:HGNC Symbol;Acc:HGNC:2746]",0,0,1,0,1,1,"no","no"]
[38650,0,"chr12","-",9229376,9275817,"ENST00000566278",32,4130,"MSTRG.3153","A2MP1","NA","NA","NA","NA","alpha-2-macroglobulin pseudogene 1 [Source:HGNC Symbol;Acc:HGNC:8]",{"v":0.01871,"d":"0.02"},{"v":0.009578,"d":"0.01"},{"v":1.95343495510545,"d":"1.95"},{"v":0.966013217892146,"d":"0.97"},1,1,"up","no"]
[74101,0,"chr16","+",66566393,66579135,"ENST00000529386",5,924,"MSTRG.5996","CMTM1","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005125(cytokine activity);GO:0005615(extracellular space);GO:0006935(chemotaxis)","NA","NA","NA","CKLF like MARVEL transmembrane domain containing 1 [Source:HGNC Symbol;Acc:HGNC:19172]",0,{"v":0.000874,"d":"0.00"},"-inf","-inf",1,1,"down","no"]
[131789,0,"chr22","+",41898676,41904973,"ENST00000435061",5,770,"MSTRG.10529","SREBF2","GO:0090370(negative regulation of cholesterol efflux);GO:0005737(cytoplasm);GO:0005634(nucleus);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0043231(intracellular membrane-bounded organelle);GO:0005654(nucleoplasm);GO:0046983(protein dimerization activity);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0005739(mitochondrion);GO:0003677(DNA binding);GO:0005794(Golgi apparatus);GO:0006629(lipid metabolic process);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0008202(steroid metabolic process);GO:0005515(protein binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0044212(transcription regulatory region DNA binding);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:2000188(regulation of cholesterol homeostasis);GO:0000139(Golgi membrane);GO:0031410(cytoplasmic vesicle);GO:0008203(cholesterol metabolic process);GO:0001078(transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0005829(cytosol);GO:0008022(protein C-terminus binding);GO:1903146(regulation of mitophagy);GO:0045540(regulation of cholesterol biosynthetic process);GO:0070888(E-box binding);GO:1903955(positive regulation of protein targeting to mitochondrion);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:0032937(SREBP-SCAP-Insig complex);GO:0071499(cellular response to laminar fluid shear stress);GO:0012507(ER to Golgi transport vesicle membrane);GO:0072368(regulation of lipid transport by negative regulation of transcription from RNA polymerase II promoter);GO:0055098(response to low-density lipoprotein particle);GO:0010886(positive regulation of cholesterol storage);GO:0009267(cellular response to starvation)","NA","NA","NA","sterol regulatory element binding transcription factor 2 [Source:HGNC Symbol;Acc:HGNC:11290]",{"v":0.155781,"d":"0.16"},0,"inf","inf",1,1,"up","no"]
[175592,0,"chr7","+",80638643,80656683,"ENST00000441109",4,499,"MSTRG.13768","CD36","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0007155(cell adhesion);GO:0005794(Golgi apparatus);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0005581(collagen trimer);GO:0006955(immune response);GO:0007166(cell surface receptor signaling pathway);GO:0005615(extracellular space);GO:0045121(membrane raft);GO:0006898(receptor-mediated endocytosis);GO:0050909(sensory perception of taste);GO:0005041(low-density lipoprotein receptor activity);GO:0008035(high-density lipoprotein particle binding);GO:0030169(low-density lipoprotein particle binding);GO:0070892(lipoteichoic acid receptor activity);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0002221(pattern recognition receptor signaling pathway);GO:0006910(phagocytosis, recognition);GO:0007204(positive regulation of cytosolic calcium ion concentration);GO:0010628(positive regulation of gene expression);GO:0010629(negative regulation of gene expression);GO:0010744(positive regulation of macrophage derived foam cell differentiation);GO:0010886(positive regulation of cholesterol storage);GO:0019915(lipid storage);GO:0030194(positive regulation of blood coagulation);GO:0030299(intestinal cholesterol absorption);GO:0030301(cholesterol transport);GO:0031623(receptor internalization);GO:0032735(positive regulation of interleukin-12 production);GO:0032755(positive regulation of interleukin-6 production);GO:0032760(positive regulation of tumor necrosis factor production);GO:0033993(response to lipid);GO:0034197(triglyceride transport);GO:0034381(plasma lipoprotein particle clearance);GO:0034383(low-density lipoprotein particle clearance);GO:0035634(response to stilbenoid);GO:0042953(lipoprotein transport);GO:0042992(negative regulation of transcription factor import into nucleus);GO:0043123(positive regulation of I-kappaB kinase/NF-kappaB signaling);GO:0043277(apoptotic cell clearance);GO:0043410(positive regulation of MAPK cascade);GO:0044130(negative regulation of growth of symbiont in host);GO:0044539(long-chain fatty acid import);GO:0045429(positive regulation of nitric oxide biosynthetic process);GO:0050702(interleukin-1 beta secretion);GO:0050731(positive regulation of peptidyl-tyrosine phosphorylation);GO:0050830(defense response to Gram-positive bacterium);GO:0050892(intestinal absorption);GO:0055096(low-density lipoprotein particle mediated signaling);GO:0060100(positive regulation of phagocytosis, engulfment);GO:0060907(positive regulation of macrophage cytokine production);GO:0070374(positive regulation of ERK1 and ERK2 cascade);GO:0070508(cholesterol import);GO:0070542(response to fatty acid);GO:0070543(response to linoleic acid);GO:0071221(cellular response to bacterial lipopeptide);GO:0071222(cellular response to lipopolysaccharide);GO:0071223(cellular response to lipoteichoic acid);GO:0071404(cellular response to low-density lipoprotein particle stimulus);GO:0071447(cellular response to hydroperoxide);GO:1900227(positive regulation of NLRP3 inflammasome complex assembly);GO:1903428(positive regulation of reactive oxygen species biosynthetic process);GO:1990000(amyloid fibril formation);GO:2000121(regulation of removal of superoxide radicals);GO:2000334(positive regulation of blood microparticle formation);GO:2000379(positive regulation of reactive oxygen species metabolic process);GO:2000505(regulation of energy homeostasis);GO:0009897(external side of plasma membrane);GO:0031526(brush border membrane);GO:0045177(apical part of cell);GO:0002479(antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent);GO:0005887(integral component of plasma membrane);GO:0043312(neutrophil degranulation);GO:0035579(specific granule membrane);GO:0009986(cell surface);GO:0016324(apical plasma membrane);GO:0002576(platelet degranulation);GO:0002224(toll-like receptor signaling pathway);GO:0002755(MyD88-dependent toll-like receptor signaling pathway);GO:0051092(positive regulation of NF-kappaB transcription factor activity);GO:0140052(-);GO:1904646(cellular response to amyloid-beta);GO:0005622(intracellular);GO:0043235(receptor complex);GO:0007596(blood coagulation);GO:0030666(endocytic vesicle membrane);GO:0006629(lipid metabolic process);GO:0001954(positive regulation of cell-matrix adhesion);GO:0008289(lipid binding);GO:0019216(regulation of lipid metabolic process);GO:0031092(platelet alpha granule membrane);GO:0038124(toll-like receptor TLR6:TLR2 signaling pathway);GO:0071726(cellular response to diacyl bacterial lipopeptide);GO:0010942(positive regulation of cell death);GO:0070053(thrombospondin receptor activity);GO:0007263(nitric oxide mediated signal transduction);GO:0001540(amyloid-beta binding);GO:0019934(cGMP-mediated signaling);GO:0050431(transforming growth factor beta binding);GO:0045335(phagocytic vesicle);GO:0071813(lipoprotein particle binding);GO:0005044(scavenger receptor activity);GO:0035325(Toll-like receptor binding);GO:0034121(regulation of toll-like receptor signaling pathway);GO:0043497(regulation of protein heterodimerization activity)","04152(AMPK signaling pathway);04512(ECM-receptor interaction);04145(Phagosome);04640(Hematopoietic cell lineage);04920(Adipocytokine signaling pathway);03320(PPAR signaling pathway);04975(Fat digestion and absorption);04979(Cholesterol metabolism);04931(Insulin resistance);05144(Malaria)","NA","NA","CD36 molecule [Source:HGNC Symbol;Acc:HGNC:1663]",0,{"v":0.085661,"d":"0.09"},"-inf","-inf",1,1,"down","no"]
[189837,0,"chr9","-",34614042,34616452,"ENST00000472074",3,542,"MSTRG.14741","DCTN3","GO:0005737(cytoplasm);GO:0005730(nucleolus);GO:0005829(cytosol);GO:0051301(cell division);GO:0005694(chromosome);GO:0005856(cytoskeleton);GO:0007049(cell cycle);GO:0048471(perinuclear region of cytoplasm);GO:0005813(centrosome);GO:0005815(microtubule organizing center);GO:0005819(spindle);GO:0030496(midbody);GO:0000775(chromosome, centromeric region);GO:0000776(kinetochore);GO:0000777(condensed chromosome kinetochore);GO:0005515(protein binding);GO:0032154(cleavage furrow);GO:0000086(G2/M transition of mitotic cell cycle);GO:0010389(regulation of G2/M transition of mitotic cell cycle);GO:0097711(ciliary basal body docking);GO:0019886(antigen processing and presentation of exogenous peptide antigen via MHC class II);GO:0006888(ER to Golgi vesicle-mediated transport);GO:0005198(structural molecule activity);GO:0000910(cytokinesis);GO:0000278(mitotic cell cycle);GO:0005869(dynactin complex);GO:0007017(microtubule-based process);GO:0005875(microtubule associated complex)","NA","NA","NA","dynactin subunit 3 [Source:HGNC Symbol;Acc:HGNC:2713]",0,{"v":0.165782,"d":"0.17"},"-inf","-inf",1,1,"down","no"]
[158971,0,"chr5","+",139341862,139368798,"ENST00000511381",3,365,"MSTRG.12364","PAIP2","GO:0005737(cytoplasm);GO:0005515(protein binding);GO:0006417(regulation of translation);GO:0030371(translation repressor activity);GO:0045947(negative regulation of translational initiation);GO:0003729(mRNA binding);GO:0007283(spermatogenesis);GO:0007613(memory);GO:0017148(negative regulation of translation);GO:1900271(regulation of long-term synaptic potentiation)","NA","NA","NA","poly(A) binding protein interacting protein 2 [Source:HGNC Symbol;Acc:HGNC:17970]",0,0,1,0,1,1,"no","no"]
[29960,0,"chr11","-",61416178,61429950,"ENST00000544669",5,1800,"MSTRG.2444","CPSF7","GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0006397(mRNA processing);GO:0005634(nucleus);GO:0016020(membrane);GO:0005515(protein binding);GO:0005849(mRNA cleavage factor complex);GO:0005654(nucleoplasm);GO:0006369(termination of RNA polymerase II transcription);GO:0031124(mRNA 3'-end processing);GO:0000398(mRNA splicing, via spliceosome);GO:0051262(protein tetramerization)","03015(mRNA surveillance pathway)","NA","NA","cleavage and polyadenylation specific factor 7 [Source:HGNC Symbol;Acc:HGNC:30098]",{"v":0.263372,"d":"0.26"},{"v":0.717415,"d":"0.72"},{"v":0.367112480224138,"d":"0.37"},{"v":-1.44570593427333,"d":"-1.45"},1,1,"down","no"]
[154494,0,"chr5","+",41925301,41941568,"ENST00000509134",6,1284,"ENSG00000151876","FBXO4","GO:0005737(cytoplasm);GO:0016567(protein ubiquitination);GO:0042803(protein homodimerization activity);GO:0005515(protein binding);GO:0005829(cytosol);GO:0000209(protein polyubiquitination);GO:0043687(post-translational protein modification);GO:0004842(ubiquitin-protein transferase activity);GO:0000151(ubiquitin ligase complex);GO:0032212(positive regulation of telomere maintenance via telomerase);GO:0031647(regulation of protein stability);GO:0031398(positive regulation of protein ubiquitination);GO:0019005(SCF ubiquitin ligase complex);GO:0031146(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process);GO:0061630(ubiquitin protein ligase activity);GO:0007568(aging);GO:0010608(posttranscriptional regulation of gene expression);GO:0019725(cellular homeostasis);GO:0031648(protein destabilization);GO:0035726(common myeloid progenitor cell proliferation);GO:0048147(negative regulation of fibroblast proliferation);GO:0071479(cellular response to ionizing radiation);GO:1900181(negative regulation of protein localization to nucleus);GO:1902916(positive regulation of protein polyubiquitination);GO:2000001(regulation of DNA damage checkpoint)","04120(Ubiquitin mediated proteolysis)","K10291","NA","F-box protein 4 [Source:HGNC Symbol;Acc:HGNC:13583]",{"v":0.356012,"d":"0.36"},{"v":0.50261,"d":"0.50"},{"v":0.70832653548477,"d":"0.71"},{"v":-0.497513505027718,"d":"-0.50"},1,1,"down","no"]
[80603,0,"chr17","+",19378892,19383544,"ENST00000490660",5,2867,"ENSG00000166484","MAPK7","GO:0050728(negative regulation of inflammatory response);GO:0034115(negative regulation of heterotypic cell-cell adhesion);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0005634(nucleus);GO:2000352(negative regulation of endothelial cell apoptotic process);GO:0005737(cytoplasm);GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0005654(nucleoplasm);GO:0016740(transferase activity);GO:0004707(MAP kinase activity);GO:0016301(kinase activity);GO:0000165(MAPK cascade);GO:0016310(phosphorylation);GO:0005515(protein binding);GO:0007049(cell cycle);GO:0030154(cell differentiation);GO:0005829(cytosol);GO:0007165(signal transduction);GO:0016605(PML body);GO:0007411(axon guidance);GO:0071560(cellular response to transforming growth factor beta stimulus);GO:2001240(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand);GO:0051247(positive regulation of protein metabolic process);GO:0060761(negative regulation of response to cytokine stimulus);GO:0071363(cellular response to growth factor stimulus);GO:0071499(cellular response to laminar fluid shear stress);GO:0019933(cAMP-mediated signaling);GO:1902176(negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway);GO:0051019(mitogen-activated protein kinase binding);GO:0070301(cellular response to hydrogen peroxide);GO:0036003(positive regulation of transcription from RNA polymerase II promoter in response to stress);GO:0030821(negative regulation of cAMP catabolic process);GO:0051344(negative regulation of cyclic-nucleotide phosphodiesterase activity);GO:0005622(intracellular);GO:0018105(peptidyl-serine phosphorylation);GO:0043066(negative regulation of apoptotic process);GO:0043407(negative regulation of MAP kinase activity);GO:0045765(regulation of angiogenesis);GO:0051534(negative regulation of NFAT protein import into nucleus);GO:0070377(negative regulation of ERK5 cascade)","04010(MAPK signaling pathway);04540(Gap junction);04657(IL-17 signaling pathway);04912(GnRH signaling pathway);04921(Oxytocin signaling pathway);04722(Neurotrophin signaling pathway);05206(MicroRNAs in cancer);05418(Fluid shear stress and atherosclerosis)","NA","NA","mitogen-activated protein kinase 7 [Source:HGNC Symbol;Acc:HGNC:6880]",{"v":0.20523,"d":"0.21"},0,"inf","inf",1,1,"up","no"]
[163283,0,"chr6","-",25014952,25042170,"ENST00000606385",3,1030,"MSTRG.12716","AL160400.1","NA","NA","NA","NA","NA",{"v":0.270698,"d":"0.27"},{"v":0.427188,"d":"0.43"},{"v":0.633674166877347,"d":"0.63"},{"v":-0.658186892796684,"d":"-0.66"},1,1,"down","no"]
[143589,0,"chr3","+",184577612,184578173,"ENST00000482987",2,482,"ENSG00000182580","EPHB3","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0004713(protein tyrosine kinase activity);GO:0005003(ephrin receptor activity);GO:0007169(transmembrane receptor protein tyrosine kinase signaling pathway);GO:0018108(peptidyl-tyrosine phosphorylation);GO:0005887(integral component of plasma membrane);GO:0005886(plasma membrane);GO:0042995(cell projection);GO:0004714(transmembrane receptor protein tyrosine kinase activity);GO:0007275(multicellular organism development);GO:0007399(nervous system development);GO:0030425(dendrite);GO:0005576(extracellular region);GO:0005829(cytosol);GO:0016477(cell migration);GO:0048538(thymus development);GO:0048013(ephrin receptor signaling pathway);GO:0060997(dendritic spine morphogenesis);GO:0046777(protein autophosphorylation);GO:0060021(palate development);GO:0001525(angiogenesis);GO:0007411(axon guidance);GO:0051965(positive regulation of synapse assembly);GO:0043087(regulation of GTPase activity);GO:0050770(regulation of axonogenesis);GO:0048546(digestive tract morphogenesis);GO:0034446(substrate adhesion-dependent cell spreading);GO:0022407(regulation of cell-cell adhesion);GO:0001655(urogenital system development);GO:0007413(axonal fasciculation);GO:0022038(corpus callosum development);GO:0060996(dendritic spine development);GO:0008046(axon guidance receptor activity);GO:0021952(central nervous system projection neuron axonogenesis);GO:0031290(retinal ganglion cell axon guidance)","04360(Axon guidance)","NA","NA","EPH receptor B3 [Source:HGNC Symbol;Acc:HGNC:3394]",{"v":0.006934,"d":"0.01"},0,"inf","inf",1,1,"up","no"]
[103090,0,"chr19","+",46661478,46671341,"ENST00000500689",3,1304,"MSTRG.8251","DACT3-AS1","NA","NA","NA","NA","DACT3 antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:44120]",{"v":0.026468,"d":"0.03"},0,"inf","inf",1,1,"up","no"]
[158452,0,"chr5","+",134525657,134579474,"ENST00000282605",12,2748,"MSTRG.12313","JADE2","GO:0005654(nucleoplasm);GO:0046872(metal ion binding);GO:0061630(ubiquitin protein ligase activity);GO:0000209(protein polyubiquitination);GO:0050767(regulation of neurogenesis);GO:0050769(positive regulation of neurogenesis);GO:0051865(protein autoubiquitination);GO:0060395(SMAD protein signal transduction);GO:1990138(neuron projection extension);GO:0016740(transferase activity);GO:0016567(protein ubiquitination);GO:0005515(protein binding);GO:0070062(extracellular exosome);GO:0043981(histone H4-K5 acetylation);GO:0043982(histone H4-K8 acetylation);GO:0000123(histone acetyltransferase complex);GO:0043966(histone H3 acetylation);GO:0043983(histone H4-K12 acetylation)","NA","NA","NA","jade family PHD finger 2 [Source:HGNC Symbol;Acc:HGNC:22984]",{"v":0.16495,"d":"0.16"},{"v":0.119293,"d":"0.12"},{"v":1.38272991709488,"d":"1.38"},{"v":0.467519388361541,"d":"0.47"},1,1,"up","no"]
[51533,0,"chr13","+",100489968,100491817,"ENST00000621936",1,1850,"MSTRG.4081","PCCA","GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0046872(metal ion binding);GO:0003824(catalytic activity);GO:0005739(mitochondrion);GO:0004075(biotin carboxylase activity);GO:0016874(ligase activity);GO:0005759(mitochondrial matrix);GO:0005829(cytosol);GO:0019899(enzyme binding);GO:0006768(biotin metabolic process);GO:0004658(propionyl-CoA carboxylase activity);GO:0009374(biotin binding);GO:0019626(short-chain fatty acid catabolic process)","00630(Glyoxylate and dicarboxylate metabolism);00640(Propanoate metabolism);00280(Valine, leucine and isoleucine degradation)","NA","NA","propionyl-CoA carboxylase alpha subunit [Source:HGNC Symbol;Acc:HGNC:8653]",{"v":0.056666,"d":"0.06"},{"v":0.027509,"d":"0.03"},{"v":2.05990766658185,"d":"2.06"},{"v":1.04257967141339,"d":"1.04"},1,1,"up","no"]
[174223,0,"chr7","+",56062619,56063620,"ENST00000466479",2,745,"MSTRG.13653","CCT6A","GO:0003723(RNA binding);GO:0005737(cytoplasm);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0005829(cytosol);GO:0006457(protein folding);GO:0005874(microtubule);GO:0051082(unfolded protein binding);GO:0061077(chaperone-mediated protein folding);GO:0070062(extracellular exosome);GO:0031012(extracellular matrix);GO:0005515(protein binding);GO:0050821(protein stabilization);GO:0032212(positive regulation of telomere maintenance via telomerase);GO:1904851(positive regulation of establishment of protein localization to telomere);GO:1904874(positive regulation of telomerase RNA localization to Cajal body);GO:0044183(protein binding involved in protein folding);GO:0006458('de novo' protein folding);GO:1904871(positive regulation of protein localization to Cajal body);GO:0005832(chaperonin-containing T-complex);GO:0071987(WD40-repeat domain binding)","NA","NA","NA","chaperonin containing TCP1 subunit 6A [Source:HGNC Symbol;Acc:HGNC:1620]",{"v":0.056705,"d":"0.06"},{"v":0.124283,"d":"0.12"},{"v":0.456257090672095,"d":"0.46"},{"v":-1.13208111497068,"d":"-1.13"},1,1,"down","no"]
[68703,0,"chr16","+",3065640,3069551,"ENST00000548652",6,812,"MSTRG.5581","IL32","GO:0016020(membrane);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0006955(immune response);GO:0005125(cytokine activity);GO:0005615(extracellular space);GO:0005829(cytosol);GO:0007155(cell adhesion);GO:0006952(defense response)","NA","NA","NA","interleukin 32 [Source:HGNC Symbol;Acc:HGNC:16830]",{"v":0.861054,"d":"0.86"},{"v":0.482534,"d":"0.48"},{"v":1.78444213257511,"d":"1.78"},{"v":0.835473117189368,"d":"0.84"},1,1,"up","no"]
[42073,0,"chr12","-",53193677,53194458,"ENST00000548269",2,486,"MSTRG.3396","ITGB7","GO:0007155(cell adhesion);GO:0004872(receptor activity);GO:0007160(cell-matrix adhesion);GO:0007229(integrin-mediated signaling pathway);GO:0008305(integrin complex);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0046872(metal ion binding);GO:0005515(protein binding);GO:0050776(regulation of immune response);GO:0005886(plasma membrane);GO:0046718(viral entry into host cell);GO:0070062(extracellular exosome);GO:0009986(cell surface);GO:0030198(extracellular matrix organization);GO:0043113(receptor clustering);GO:0001618(virus receptor activity);GO:0043235(receptor complex);GO:0050839(cell adhesion molecule binding);GO:0034446(substrate adhesion-dependent cell spreading);GO:0034113(heterotypic cell-cell adhesion);GO:0050901(leukocyte tethering or rolling);GO:0003366(cell-matrix adhesion involved in ameboidal cell migration);GO:0034669(integrin alpha4-beta7 complex);GO:0050900(leukocyte migration);GO:0072678(T cell migration)","04151(PI3K-Akt signaling pathway);04512(ECM-receptor interaction);04514(Cell adhesion molecules (CAMs));04510(Focal adhesion);04810(Regulation of actin cytoskeleton);04672(Intestinal immune network for IgA production);05202(Transcriptional misregulation in cancers);05410(Hypertrophic cardiomyopathy (HCM));05412(Arrhythmogenic right ventricular cardiomyopathy (ARVC));05414(Dilated cardiomyopathy (DCM));05165(Human papillomavirus infection)","NA","NA","integrin subunit beta 7 [Source:HGNC Symbol;Acc:HGNC:6162]",{"v":0.077019,"d":"0.08"},{"v":0.105535,"d":"0.11"},{"v":0.729795802340456,"d":"0.73"},{"v":-0.454435242074072,"d":"-0.45"},1,1,"down","no"]
[87920,0,"chr17","-",75237526,75239081,"ENST00000583282",3,550,"MSTRG.7208","GGA3","GO:0006810(transport);GO:0016020(membrane);GO:0006886(intracellular protein transport);GO:0015031(protein transport);GO:0016192(vesicle-mediated transport);GO:0005794(Golgi apparatus);GO:0005622(intracellular);GO:0030131(clathrin adaptor complex);GO:0005515(protein binding);GO:0005802(trans-Golgi network);GO:0030306(ADP-ribosylation factor binding);GO:0005768(endosome);GO:0044267(cellular protein metabolic process);GO:0061024(membrane organization);GO:0010008(endosome membrane);GO:0031901(early endosome membrane);GO:0055038(recycling endosome membrane);GO:0045732(positive regulation of protein catabolic process)","04142(Lysosome)","NA","NA","golgi associated, gamma adaptin ear containing, ARF binding protein 3 [Source:HGNC Symbol;Acc:HGNC:17079]",0,{"v":0.137598,"d":"0.14"},"-inf","-inf",1,1,"down","no"]
[101654,0,"chr19","-",40705334,40714635,"ENST00000594490",4,406,"MSTRG.8155","COQ8B","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0005739(mitochondrion);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0006744(ubiquinone biosynthetic process);GO:0031966(mitochondrial membrane);GO:0021692(cerebellar Purkinje cell layer morphogenesis)","NA","NA","NA","coenzyme Q8B [Source:HGNC Symbol;Acc:HGNC:19041]",{"v":0.087754,"d":"0.09"},{"v":0.092094,"d":"0.09"},{"v":0.952874237192434,"d":"0.95"},{"v":-0.0696422788125488,"d":"-0.07"},1,1,"down","no"]
[57061,0,"chr14","+",76154354,76212803,"ENST00000621494",9,12396,"ENSG00000089916","GPATCH2L","GO:0005515(protein binding)","NA","NA","NA","G-patch domain containing 2 like [Source:HGNC Symbol;Acc:HGNC:20210]",0,{"v":0.023844,"d":"0.02"},"-inf","-inf",1,1,"down","no"]
[54869,0,"chr14","-",50475092,50561126,"ENST00000555216",9,592,"ENSG00000012983","MAP4K5","GO:0005622(intracellular);GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0000165(MAPK cascade);GO:0016310(phosphorylation);GO:0008349(MAP kinase kinase kinase kinase activity);GO:0000185(activation of MAPKKK activity)","NA","NA","NA","mitogen-activated protein kinase kinase kinase kinase 5 [Source:HGNC Symbol;Acc:HGNC:6867]",{"v":0.08765,"d":"0.09"},{"v":0.000149,"d":"0.00"},{"v":588.255033557047,"d":"588.26"},{"v":9.2002979500721,"d":"9.20"},1,1,"up","no"]
[28782,0,"chr11","+",47269677,47274997,"ENST00000534808",2,509,"ENSG00000110514","MADD","GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0043547(positive regulation of GTPase activity);GO:0005515(protein binding);GO:0006915(apoptotic process);GO:0005085(guanyl-nucleotide exchange factor activity);GO:0017112(Rab guanyl-nucleotide exchange factor activity);GO:0061024(membrane organization);GO:0042981(regulation of apoptotic process);GO:0007166(cell surface receptor signaling pathway);GO:0051726(regulation of cell cycle);GO:0010803(regulation of tumor necrosis factor-mediated signaling pathway);GO:0000187(activation of MAPK activity);GO:0097194(execution phase of apoptosis);GO:0032483(regulation of Rab protein signal transduction);GO:0030295(protein kinase activator activity);GO:1902041(regulation of extrinsic apoptotic signaling pathway via death domain receptors);GO:0005123(death receptor binding);GO:2001236(regulation of extrinsic apoptotic signaling pathway)","NA","NA","NA","MAP kinase activating death domain [Source:HGNC Symbol;Acc:HGNC:6766]",0,0,1,0,1,1,"no","no"]
[14908,0,"chr1","+",202225423,202236334,"ENST00000503519",3,557,"ENSG00000133067","LGR6","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0007186(G-protein coupled receptor signaling pathway);GO:0005886(plasma membrane);GO:0004871(signal transducer activity);GO:0007165(signal transduction);GO:0016055(Wnt signaling pathway);GO:0005887(integral component of plasma membrane);GO:0005515(protein binding);GO:0030335(positive regulation of cell migration);GO:0090263(positive regulation of canonical Wnt signaling pathway);GO:0004888(transmembrane signaling receptor activity);GO:0031982(vesicle);GO:0032588(trans-Golgi network membrane);GO:0030177(positive regulation of Wnt signaling pathway);GO:0042246(tissue regeneration);GO:1990523(bone regeneration)","NA","NA","NA","leucine rich repeat containing G protein-coupled receptor 6 [Source:HGNC Symbol;Acc:HGNC:19719]",0,0,1,0,1,1,"no","no"]
[37293,0,"chr12","-",913234,916582,"ENST00000535376",4,808,"MSTRG.3009","RAD52","GO:0005634(nucleus);GO:0003677(DNA binding);GO:0006281(DNA repair);GO:0005515(protein binding);GO:0006310(DNA recombination);GO:0006974(cellular response to DNA damage stimulus);GO:0000724(double-strand break repair via homologous recombination);GO:0042802(identical protein binding);GO:0005654(nucleoplasm);GO:0043234(protein complex);GO:0000730(DNA recombinase assembly);GO:0045002(double-strand break repair via single-strand annealing);GO:0051260(protein homooligomerization);GO:0006302(double-strand break repair);GO:0032993(protein-DNA complex);GO:0034599(cellular response to oxidative stress);GO:0003697(single-stranded DNA binding);GO:0010792(DNA double-strand break processing involved in repair via single-strand annealing);GO:2000819(regulation of nucleotide-excision repair)","03440(Homologous recombination)","NA","NA","RAD52 homolog, DNA repair protein [Source:HGNC Symbol;Acc:HGNC:9824]",{"v":0.3289,"d":"0.33"},{"v":0.172311,"d":"0.17"},{"v":1.90875800152051,"d":"1.91"},{"v":0.932634204817678,"d":"0.93"},1,1,"up","no"]
[52200,0,"chr14","+",19677837,19680104,"ENST00000547785",1,2268,"ENSG00000257884","AL512310.7","NA","NA","NA","NA","NA",0,0,1,0,1,1,"no","no"]
[156924,0,"chr5","+",96702806,96772892,"ENST00000504465",27,2336,"MSTRG.12236","CAST","GO:0003723(RNA binding);GO:0005783(endoplasmic reticulum);GO:0005829(cytosol);GO:0005515(protein binding);GO:0004869(cysteine-type endopeptidase inhibitor activity);GO:0030414(peptidase inhibitor activity);GO:0010466(negative regulation of peptidase activity);GO:0045296(cadherin binding);GO:0004866(endopeptidase inhibitor activity);GO:0016020(membrane);GO:2000675(negative regulation of type B pancreatic cell apoptotic process);GO:0010859(calcium-dependent cysteine-type endopeptidase inhibitor activity);GO:0097340(inhibition of cysteine-type endopeptidase activity)","NA","NA","NA","calpastatin [Source:HGNC Symbol;Acc:HGNC:1515]",{"v":0.356691,"d":"0.36"},{"v":0.232713,"d":"0.23"},{"v":1.53275064134793,"d":"1.53"},{"v":0.616123008312823,"d":"0.62"},1,1,"up","no"]
[175325,0,"chr7","+",76461697,76480584,"ENST00000456590",3,569,"MSTRG.13744","DTX2","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0005654(nucleoplasm);GO:0016740(transferase activity);GO:0016567(protein ubiquitination);GO:0031965(nuclear membrane);GO:0005515(protein binding);GO:0007219(Notch signaling pathway)","04330(Notch signaling pathway)","NA","NA","deltex E3 ubiquitin ligase 2 [Source:HGNC Symbol;Acc:HGNC:15973]",{"v":0.161948,"d":"0.16"},0,"inf","inf",1,1,"up","no"]
[133601,0,"chr3","+",14145373,14148531,"ENST00000629708",2,661,"MSTRG.10677","AC093495.1","NA","NA","NA","NA","NA",0,0,1,0,1,1,"no","no"]
[90051,0,"chr17","+",83094249,83094847,"ENST00000574053",2,545,"MSTRG.7378","METRNL","GO:0005576(extracellular region);GO:0005615(extracellular space);GO:0005179(hormone activity);GO:0003674(molecular_function);GO:0070062(extracellular exosome);GO:0045444(fat cell differentiation);GO:0050728(negative regulation of inflammatory response);GO:0014850(response to muscle activity);GO:0050873(brown fat cell differentiation);GO:0009409(response to cold);GO:0090336(positive regulation of brown fat cell differentiation);GO:2000507(positive regulation of energy homeostasis)","NA","NA","NA","meteorin like, glial cell differentiation regulator [Source:HGNC Symbol;Acc:HGNC:27584]",{"v":0.000161,"d":"0.00"},0,"inf","inf",1,1,"up","no"]
[168259,0,"chr6","-",108922976,108924103,"ENST00000426737",2,112,"ENSG00000230290","ARMC2-AS1","NA","NA","NA","NA","ARMC2 antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:41008]",{"v":0.246137,"d":"0.25"},0,"inf","inf",1,1,"up","no"]
[96212,0,"chr19","-",9810861,9827816,"ENST00000585379",3,956,"MSTRG.7779","FBXL12","GO:0016567(protein ubiquitination);GO:0005515(protein binding);GO:0005829(cytosol);GO:0000209(protein polyubiquitination);GO:0043687(post-translational protein modification);GO:0004842(ubiquitin-protein transferase activity);GO:0006511(ubiquitin-dependent protein catabolic process);GO:0000151(ubiquitin ligase complex);GO:0005737(cytoplasm)","NA","NA","NA","F-box and leucine rich repeat protein 12 [Source:HGNC Symbol;Acc:HGNC:13611]",{"v":0.002806,"d":"0.00"},{"v":0.041737,"d":"0.04"},{"v":0.0672305148908642,"d":"0.07"},{"v":-3.89473999115496,"d":"-3.89"},1,1,"down","no"]
[129293,0,"chr22","+",23179704,23261428,"ENST00000479188",5,658,"MSTRG.10230","BCR","GO:0016020(membrane);GO:0000166(nucleotide binding);GO:0004674(protein serine/threonine kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0035556(intracellular signal transduction);GO:0007165(signal transduction);GO:0018108(peptidyl-tyrosine phosphorylation);GO:0005886(plasma membrane);GO:0005089(Rho guanyl-nucleotide exchange factor activity);GO:0035023(regulation of Rho protein signal transduction);GO:0005515(protein binding);GO:0005096(GTPase activator activity);GO:0030054(cell junction);GO:0045202(synapse);GO:0045211(postsynaptic membrane);GO:0005085(guanyl-nucleotide exchange factor activity);GO:0043547(positive regulation of GTPase activity);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0051056(regulation of small GTPase mediated signal transduction);GO:0014069(postsynaptic density);GO:0043234(protein complex);GO:0004713(protein tyrosine kinase activity);GO:0019899(enzyme binding);GO:0002692(negative regulation of cellular extravasation);GO:0003014(renal system process);GO:0007420(brain development);GO:0030036(actin cytoskeleton organization);GO:0030336(negative regulation of cell migration);GO:0032496(response to lipopolysaccharide);GO:0042472(inner ear morphogenesis);GO:0043114(regulation of vascular permeability);GO:0043314(negative regulation of neutrophil degranulation);GO:0046777(protein autophosphorylation);GO:0048008(platelet-derived growth factor receptor signaling pathway);GO:0048872(homeostasis of number of cells);GO:0050728(negative regulation of inflammatory response);GO:0050766(positive regulation of phagocytosis);GO:0050885(neuromuscular process controlling balance);GO:0051171(regulation of nitrogen compound metabolic process);GO:0051726(regulation of cell cycle);GO:0060216(definitive hemopoiesis);GO:0060268(negative regulation of respiratory burst);GO:0060313(negative regulation of blood vessel remodeling);GO:0065002(intracellular protein transmembrane transport);GO:0071222(cellular response to lipopolysaccharide);GO:2000378(negative regulation of reactive oxygen species metabolic process);GO:0005737(cytoplasm);GO:0005622(intracellular)","05200(Pathways in cancer);05220(Chronic myeloid leukemia)","NA","NA","BCR, RhoGEF and GTPase activating protein [Source:HGNC Symbol;Acc:HGNC:1014]",{"v":0.118262,"d":"0.12"},0,"inf","inf",1,1,"up","no"]
[132613,0,"chr22","-",50576626,50578465,"ENST00000460853",4,757,"MSTRG.10612","CPT1B","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016740(transferase activity);GO:0016746(transferase activity, transferring acyl groups);GO:0006629(lipid metabolic process);GO:0006631(fatty acid metabolic process);GO:0005739(mitochondrion);GO:0005515(protein binding);GO:0005741(mitochondrial outer membrane);GO:0006853(carnitine shuttle);GO:0006635(fatty acid beta-oxidation);GO:0004095(carnitine O-palmitoyltransferase activity);GO:0015909(long-chain fatty acid transport);GO:0043231(intracellular membrane-bounded organelle)","00071(Fatty acid degradation);04152(AMPK signaling pathway);04922(Glucagon signaling pathway);04920(Adipocytokine signaling pathway);03320(PPAR signaling pathway);04931(Insulin resistance)","NA","NA","carnitine palmitoyltransferase 1B [Source:HGNC Symbol;Acc:HGNC:2329]",0,{"v":0.226336,"d":"0.23"},"-inf","-inf",1,1,"down","no"]
[188372,0,"chr8","-",144412414,144413586,"ENST00000532718",4,668,"ENSG00000147804","SLC39A4","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0055085(transmembrane transport);GO:0006811(ion transport);GO:0005886(plasma membrane);GO:0046873(metal ion transmembrane transporter activity);GO:0030001(metal ion transport);GO:0031410(cytoplasmic vesicle);GO:0005887(integral component of plasma membrane);GO:0005768(endosome);GO:0070062(extracellular exosome);GO:0007165(signal transduction);GO:0055038(recycling endosome membrane);GO:0006829(zinc II ion transport);GO:0005385(zinc ion transmembrane transporter activity);GO:0006882(cellular zinc ion homeostasis);GO:0071578(zinc II ion transmembrane import);GO:0034224(cellular response to zinc ion starvation);GO:0016324(apical plasma membrane)","04978(Mineral absorption)","NA","NA","solute carrier family 39 member 4 [Source:HGNC Symbol;Acc:HGNC:17129]",{"v":0.703089,"d":"0.70"},{"v":1.717104,"d":"1.72"},{"v":0.409462094316943,"d":"0.41"},{"v":-1.28819819338046,"d":"-1.29"},1,1,"down","no"]
[95778,0,"chr19","-",7728957,7732171,"ENST00000328853",9,1360,"ENSG00000182566","CLEC4G","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0030246(carbohydrate binding);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0050776(regulation of immune response);GO:0046718(viral entry into host cell);GO:0016032(viral process);GO:0001618(virus receptor activity);GO:0030247(polysaccharide binding);GO:0002710(negative regulation of T cell mediated immunity);GO:0042130(negative regulation of T cell proliferation)","NA","NA","NA","C-type lectin domain family 4 member G [Source:HGNC Symbol;Acc:HGNC:24591]",{"v":0.09192,"d":"0.09"},{"v":0.14931,"d":"0.15"},{"v":0.615631906771147,"d":"0.62"},{"v":-0.699860089752062,"d":"-0.70"},1,1,"down","no"]
[179210,0,"chr7","+",139374673,139412825,"ENST00000463912",7,2382,"MSTRG.14004","LUC7L2","GO:0003723(RNA binding);GO:0003729(mRNA binding);GO:0005634(nucleus);GO:0016607(nuclear speck);GO:0005515(protein binding);GO:0005654(nucleoplasm);GO:0005685(U1 snRNP);GO:0006376(mRNA splice site selection);GO:0019899(enzyme binding);GO:0071004(U2-type prespliceosome)","NA","NA","NA","LUC7 like 2, pre-mRNA splicing factor [Source:HGNC Symbol;Acc:HGNC:21608]",{"v":0.501847,"d":"0.50"},0,"inf","inf",1,1,"up","no"]
[116620,0,"chr2","-",175126793,175168144,"ENST00000413123",6,681,"ENSG00000115966","ATF2","GO:0005634(nucleus);GO:0003676(nucleic acid binding);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0046872(metal ion binding);GO:0005654(nucleoplasm);GO:0016740(transferase activity);GO:0006355(regulation of transcription, DNA-templated);GO:0006366(transcription from RNA polymerase II promoter);GO:0006351(transcription, DNA-templated);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0005739(mitochondrion);GO:0005515(protein binding);GO:0006974(cellular response to DNA damage stimulus);GO:0005741(mitochondrial outer membrane);GO:0004402(histone acetyltransferase activity);GO:0016573(histone acetylation);GO:0019901(protein kinase binding);GO:0001228(transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0003713(transcription coactivator activity);GO:0000980(RNA polymerase II distal enhancer sequence-specific DNA binding);GO:0051091(positive regulation of sequence-specific DNA binding transcription factor activity);GO:0000977(RNA polymerase II regulatory region sequence-specific DNA binding);GO:0001102(RNA polymerase II activating transcription factor binding);GO:0003705(transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding);GO:0006970(response to osmotic stress);GO:0110024(-);GO:0035861(site of double-strand break);GO:0001158(enhancer sequence-specific DNA binding);GO:0051090(regulation of sequence-specific DNA binding transcription factor activity);GO:0035497(cAMP response element binding);GO:0001076(transcription factor activity, RNA polymerase II transcription factor binding);GO:0001077(transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0003682(chromatin binding);GO:0008134(transcription factor binding);GO:0008140(cAMP response element binding protein binding);GO:0043565(sequence-specific DNA binding);GO:0046982(protein heterodimerization activity);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0003151(outflow tract morphogenesis);GO:0009414(response to water deprivation);GO:0031573(intra-S DNA damage checkpoint);GO:0032915(positive regulation of transforming growth factor beta2 production);GO:0043525(positive regulation of neuron apoptotic process);GO:0045444(fat cell differentiation);GO:0050680(negative regulation of epithelial cell proliferation);GO:0060612(adipose tissue development);GO:0097186(amelogenesis);GO:1902110(positive regulation of mitochondrial membrane permeability involved in apoptotic process)","04010(MAPK signaling pathway);04668(TNF signaling pathway);04022(cGMP - PKG signaling pathway);04151(PI3K-Akt signaling pathway);04911(Insulin secretion);04922(Glucagon signaling pathway);04915(Estrogen signaling pathway);04926(Relaxin signaling pathway);04918(Thyroid hormone synthesis);04925(Aldosterone synthesis and secretion);04927(Cortisol synthesis and secretion);04261(Adrenergic signaling in cardiomyocytes);04728(Dopaminergic synapse);04211(Longevity regulating pathway - mammal);05203(Viral carcinogenesis);05030(Cocaine addiction);05031(Amphetamine addiction);05034(Alcoholism);05166(HTLV-I infection);05164(Influenza A);05161(Hepatitis B);05169(Epstein-Barr virus infection)","NA","NA","activating transcription factor 2 [Source:HGNC Symbol;Acc:HGNC:784]",{"v":0.206262,"d":"0.21"},{"v":0.239897,"d":"0.24"},{"v":0.859793994922821,"d":"0.86"},{"v":-0.217937060776104,"d":"-0.22"},1,1,"down","no"]
[135388,0,"chr3","+",44625095,44647778,"ENST00000334075",7,2320,"ENSG00000186448","ZNF197","GO:0005634(nucleus);GO:0006355(regulation of transcription, DNA-templated);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0003676(nucleic acid binding);GO:0046872(metal ion binding);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0005622(intracellular)","NA","NA","NA","zinc finger protein 197 [Source:HGNC Symbol;Acc:HGNC:12988]",{"v":0.4718,"d":"0.47"},{"v":0.042976,"d":"0.04"},{"v":10.9782204020849,"d":"10.98"},{"v":3.45657230358675,"d":"3.46"},1,1,"up","no"]
[177882,0,"chr7","+",112486123,112489967,"ENST00000486022",3,604,"MSTRG.13917","LSMEM1","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005829(cytosol);GO:0005515(protein binding)","NA","NA","NA","leucine rich single-pass membrane protein 1 [Source:HGNC Symbol;Acc:HGNC:22036]",{"v":0.099376,"d":"0.10"},{"v":0.431504,"d":"0.43"},{"v":0.23030145722867,"d":"0.23"},{"v":-2.11840455509866,"d":"-2.12"},1,1,"down","no"]
[174217,0,"chr7","+",56056312,56059010,"ENST00000482776",4,765,"MSTRG.13653","CCT6A","GO:0003723(RNA binding);GO:0005737(cytoplasm);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0005829(cytosol);GO:0006457(protein folding);GO:0005874(microtubule);GO:0051082(unfolded protein binding);GO:0061077(chaperone-mediated protein folding);GO:0070062(extracellular exosome);GO:0031012(extracellular matrix);GO:0005515(protein binding);GO:0050821(protein stabilization);GO:0032212(positive regulation of telomere maintenance via telomerase);GO:1904851(positive regulation of establishment of protein localization to telomere);GO:1904874(positive regulation of telomerase RNA localization to Cajal body);GO:0044183(protein binding involved in protein folding);GO:0006458('de novo' protein folding);GO:1904871(positive regulation of protein localization to Cajal body);GO:0005832(chaperonin-containing T-complex);GO:0071987(WD40-repeat domain binding)","NA","NA","NA","chaperonin containing TCP1 subunit 6A [Source:HGNC Symbol;Acc:HGNC:1620]",{"v":0.409466,"d":"0.41"},{"v":0.347138,"d":"0.35"},{"v":1.17954819120926,"d":"1.18"},{"v":0.238234362026587,"d":"0.24"},1,1,"up","no"]
[162948,0,"chr6","-",13306398,13328531,"ENST00000450347",6,958,"ENSG00000145979","TBC1D7","GO:0032007(negative regulation of TOR signaling);GO:0090630(activation of GTPase activity);GO:0005515(protein binding);GO:0031410(cytoplasmic vesicle);GO:0005096(GTPase activator activity);GO:0005829(cytosol);GO:0043547(positive regulation of GTPase activity);GO:0061024(membrane organization);GO:0036064(ciliary basal body);GO:0031398(positive regulation of protein ubiquitination);GO:0017137(Rab GTPase binding);GO:1902018(negative regulation of cilium assembly);GO:0070848(response to growth factor)","04150(mTOR signaling pathway)","NA","NA","TBC1 domain family member 7 [Source:HGNC Symbol;Acc:HGNC:21066]",{"v":0.257547,"d":"0.26"},0,"inf","inf",1,1,"up","no"]
[71989,0,"chr16","+",30650985,30656413,"ENST00000287463",11,2124,"MSTRG.5855","PRR14","GO:0005515(protein binding)","NA","NA","NA","proline rich 14 [Source:HGNC Symbol;Acc:HGNC:28458]",0,{"v":0.295774,"d":"0.30"},"-inf","-inf",1,1,"down","no"]
[119996,0,"chr2","-",230520594,230580006,"ENST00000455357",7,571,"MSTRG.9480","AC010149.1","NA","NA","NA","NA","NA",{"v":0.157677,"d":"0.16"},{"v":0.056718,"d":"0.06"},{"v":2.78001692584365,"d":"2.78"},{"v":1.47509366667409,"d":"1.48"},1,1,"up","no"]
[139227,0,"chr3","-",113653239,113670233,"ENST00000496826",3,8397,"ENSG00000176542","USF3","GO:0046983(protein dimerization activity);GO:0005634(nucleus);GO:0003677(DNA binding);GO:0005783(endoplasmic reticulum);GO:0000139(Golgi membrane);GO:0004571(mannosyl-oligosaccharide 1,2-alpha-mannosidase activity);GO:0006491(N-glycan processing)","NA","NA","NA","upstream transcription factor family member 3 [Source:HGNC Symbol;Acc:HGNC:30494]",{"v":0.029099,"d":"0.03"},0,"inf","inf",1,1,"up","no"]
[141722,0,"chr3","+",150703564,150719988,"ENST00000471093",3,302,"ENSG00000240137","ERICH6-AS1","NA","NA","NA","NA","ERICH6 antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:41205]",0,{"v":0.419157,"d":"0.42"},"-inf","-inf",1,1,"down","no"]
[81768,0,"chr17","+",30954240,30956728,"ENST00000480980",2,804,"ENSG00000184060","ADAP2","GO:0046872(metal ion binding);GO:0043547(positive regulation of GTPase activity);GO:0005096(GTPase activator activity);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0007507(heart development);GO:0005546(phosphatidylinositol-4,5-bisphosphate binding);GO:0005547(phosphatidylinositol-3,4,5-trisphosphate binding);GO:0043325(phosphatidylinositol-3,4-bisphosphate binding);GO:0030674(protein binding, bridging);GO:0043533(inositol 1,3,4,5 tetrakisphosphate binding);GO:0005740(mitochondrial envelope)","NA","NA","NA","ArfGAP with dual PH domains 2 [Source:HGNC Symbol;Acc:HGNC:16487]",{"v":0.13813,"d":"0.14"},{"v":0.063583,"d":"0.06"},{"v":2.17243602849818,"d":"2.17"},{"v":1.11931369477166,"d":"1.12"},1,1,"up","no"]
[102279,0,"chr19","-",43506792,43527205,"ENST00000594342",6,702,"MSTRG.8209","ETHE1","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0005654(nucleoplasm);GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0005739(mitochondrion);GO:0005759(mitochondrial matrix);GO:0051213(dioxygenase activity);GO:0005506(iron ion binding);GO:0006749(glutathione metabolic process);GO:0050313(sulfur dioxygenase activity);GO:0070221(sulfide oxidation, using sulfide:quinone oxidoreductase);GO:0070813(hydrogen sulfide metabolic process)","00920(Sulfur metabolism)","NA","NA","ETHE1, persulfide dioxygenase [Source:HGNC Symbol;Acc:HGNC:23287]",{"v":0.897293,"d":"0.90"},{"v":0.565235,"d":"0.57"},{"v":1.5874689288526,"d":"1.59"},{"v":0.66672835463822,"d":"0.67"},1,1,"up","no"]
[115326,0,"chr2","-",151836234,151973954,"ENST00000636507",13,4688,"ENSG00000182389","CACNB4","GO:0006810(transport);GO:0005244(voltage-gated ion channel activity);GO:0006811(ion transport);GO:0034765(regulation of ion transmembrane transport);GO:0005515(protein binding);GO:0006816(calcium ion transport);GO:0070588(calcium ion transmembrane transport);GO:0005245(voltage-gated calcium channel activity);GO:0005262(calcium channel activity);GO:0005891(voltage-gated calcium channel complex);GO:0005886(plasma membrane);GO:0005829(cytosol);GO:0061337(cardiac conduction);GO:0008331(high voltage-gated calcium channel activity);GO:0007268(chemical synaptic transmission);GO:0007528(neuromuscular junction development);GO:0051899(membrane depolarization);GO:1901385(regulation of voltage-gated calcium channel activity);GO:0009898(cytoplasmic side of plasma membrane)","04010(MAPK signaling pathway);04921(Oxytocin signaling pathway);04260(Cardiac muscle contraction);04261(Adrenergic signaling in cardiomyocytes);05410(Hypertrophic cardiomyopathy (HCM));05412(Arrhythmogenic right ventricular cardiomyopathy (ARVC));05414(Dilated cardiomyopathy (DCM))","NA","NA","calcium voltage-gated channel auxiliary subunit beta 4 [Source:HGNC Symbol;Acc:HGNC:1404]",0,0,1,0,1,1,"no","no"]
[182966,0,"chr8","+",37762655,37766716,"ENST00000523994",5,559,"MSTRG.14296","PLPBP","GO:0005737(cytoplasm);GO:0005622(intracellular);GO:0008150(biological_process);GO:0070062(extracellular exosome);GO:0030170(pyridoxal phosphate binding);GO:0005739(mitochondrion)","NA","NA","NA","pyridoxal phosphate binding protein [Source:HGNC Symbol;Acc:HGNC:9457]",{"v":0.251865,"d":"0.25"},{"v":0.332031,"d":"0.33"},{"v":0.75855868879713,"d":"0.76"},{"v":-0.398667290471638,"d":"-0.40"},1,1,"down","no"]
[7896,0,"chr1","+",89821014,89933160,"ENST00000525774",4,588,"MSTRG.699","LRRC8D","GO:0006810(transport);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0006811(ion transport);GO:0005886(plasma membrane);GO:0005887(integral component of plasma membrane);GO:0005515(protein binding);GO:0007165(signal transduction);GO:0055085(transmembrane transport);GO:0044070(regulation of anion transport);GO:0034702(ion channel complex);GO:0005225(volume-sensitive anion channel activity);GO:0098656(anion transmembrane transport)","NA","NA","NA","leucine rich repeat containing 8 family member D [Source:HGNC Symbol;Acc:HGNC:16992]",{"v":0.05347,"d":"0.05"},{"v":0.144661,"d":"0.14"},{"v":0.36962277324227,"d":"0.37"},{"v":-1.43587444789655,"d":"-1.44"},1,1,"down","no"]
[91186,0,"chr18","-",22200619,22205229,"ENST00000583442",2,770,"ENSG00000266283","AC091588.3","NA","NA","NA","NA","NA",0,0,1,0,1,1,"no","no"]
[52092,0,"chr13","+",114281637,114283729,"ENST00000618700",3,1210,"MSTRG.4125","UPF3A","GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0006810(transport);GO:0051028(mRNA transport);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0043231(intracellular membrane-bounded organelle);GO:0005829(cytosol);GO:0006913(nucleocytoplasmic transport);GO:0005515(protein binding);GO:0045727(positive regulation of translation);GO:0035145(exon-exon junction complex);GO:0000184(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay);GO:0042162(telomeric DNA binding);GO:0005487(nucleocytoplasmic transporter activity);GO:0005622(intracellular)","03013(RNA transport);03015(mRNA surveillance pathway)","NA","NA","UPF3A, regulator of nonsense mediated mRNA decay [Source:HGNC Symbol;Acc:HGNC:20332]",{"v":0.641717,"d":"0.64"},{"v":0.406962,"d":"0.41"},{"v":1.57684746978833,"d":"1.58"},{"v":0.657043113379739,"d":"0.66"},1,1,"up","no"]
[166085,"j","chr6","+",42929200,42941142,"MSTRG.13045.3",7,3393,"MSTRG.13045","CNPY3","NA","NA","NA","NA","NA",0,{"v":8.471363,"d":"8.47"},"-inf","-inf",1,1,"down","no"]
[99826,0,"chr19","+",34481638,34512304,"ENST00000590071",8,13665,"ENSG00000142279","WTIP","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0030054(cell junction);GO:0031047(gene silencing by RNA);GO:1903507(negative regulation of nucleic acid-templated transcription);GO:0000932(P-body);GO:0005515(protein binding);GO:0003714(transcription corepressor activity);GO:0001666(response to hypoxia);GO:0007010(cytoskeleton organization);GO:0022604(regulation of cell morphogenesis);GO:0035195(gene silencing by miRNA);GO:0035331(negative regulation of hippo signaling);GO:2000637(positive regulation of gene silencing by miRNA);GO:0005667(transcription factor complex);GO:0005911(cell-cell junction);GO:0005912(adherens junction)","04390(Hippo signaling pathway);04392(Hippo signaling pathway - multiple species)","K16682","NA","WT1 interacting protein [Source:HGNC Symbol;Acc:HGNC:20964]",{"v":7.234E-3,"d":"0.01"},0,"inf","inf",1,1,"up","no"]
[85749,0,"chr17","-",51177427,51225224,"ENST00000415868",15,5099,"MSTRG.7033","MBTD1","GO:0005634(nucleus);GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0016569(covalent chromatin modification);GO:0035064(methylated histone binding);GO:0048706(embryonic skeletal system development)","NA","NA","NA","mbt domain containing 1 [Source:HGNC Symbol;Acc:HGNC:19866]",0,0,1,0,1,1,"no","no"]
[38725,0,"chr12","+",9867027,9869808,"ENST00000545258",2,719,"MSTRG.3131","AC091814.1","NA","NA","NA","NA","NA",{"v":0.03525,"d":"0.04"},0,"inf","inf",1,1,"up","no"]
[95990,0,"chr19","-",8522810,8527387,"ENST00000600885",4,637,"MSTRG.7774","MYO1F","GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0003774(motor activity);GO:0016459(myosin complex);GO:0003779(actin binding);GO:0005516(calmodulin binding);GO:0008150(biological_process);GO:0016461(unconventional myosin complex)","NA","NA","NA","myosin IF [Source:HGNC Symbol;Acc:HGNC:7600]",{"v":0.313752,"d":"0.31"},{"v":0.433697,"d":"0.43"},{"v":0.723435947216605,"d":"0.72"},{"v":-0.467062808225391,"d":"-0.47"},1,1,"down","no"]
[48021,0,"chr12","+",123233458,123253783,"ENST00000536130",2,604,"MSTRG.3840","C12orf65","GO:0006412(translation);GO:0005739(mitochondrion);GO:0003747(translation release factor activity);GO:0006415(translational termination);GO:0072344(rescue of stalled ribosome);GO:0004045(aminoacyl-tRNA hydrolase activity);GO:0016150(translation release factor activity, codon nonspecific);GO:0070126(mitochondrial translational termination);GO:0005762(mitochondrial large ribosomal subunit)","NA","NA","NA","chromosome 12 open reading frame 65 [Source:HGNC Symbol;Acc:HGNC:26784]",0,{"v":0.000551,"d":"0.00"},"-inf","-inf",1,1,"down","no"]
[8104,0,"chr1","-",93264677,93315268,"ENST00000427669",5,383,"MSTRG.718","CCDC18-AS1","NA","NA","NA","NA","CCDC18 antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:52262]",0,0,1,0,1,1,"no","no"]
[156987,0,"chr5","-",97178830,97183160,"ENST00000511920",2,399,"ENSG00000058729","RIOK2","GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0042254(ribosome biogenesis);GO:0042274(ribosomal small subunit biogenesis);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0006364(rRNA processing);GO:0030490(maturation of SSU-rRNA);GO:0030688(preribosome, small subunit precursor);GO:2000234(positive regulation of rRNA processing);GO:2000208(positive regulation of ribosomal small subunit export from nucleus)","03008(Ribosome biogenesis in eukaryotes)","NA","NA","RIO kinase 2 [Source:HGNC Symbol;Acc:HGNC:18999]",{"v":0.095408,"d":"0.10"},{"v":0.024709,"d":"0.02"},{"v":3.86126512606743,"d":"3.86"},{"v":1.94907361745789,"d":"1.95"},1,1,"up","no"]
[71445,0,"chr16","+",28986212,28990513,"ENST00000570232",8,707,"MSTRG.5787","LAT","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0007165(signal transduction);GO:0009967(positive regulation of signal transduction);GO:0005886(plasma membrane);GO:0043547(positive regulation of GTPase activity);GO:0005515(protein binding);GO:0002376(immune system process);GO:0002250(adaptive immune response);GO:0038095(Fc-epsilon receptor signaling pathway);GO:0042629(mast cell granule);GO:0019901(protein kinase binding);GO:0008180(COP9 signalosome);GO:0000165(MAPK cascade);GO:0050852(T cell receptor signaling pathway);GO:0030168(platelet activation);GO:0042110(T cell activation);GO:0043303(mast cell degranulation);GO:0005088(Ras guanyl-nucleotide exchange factor activity);GO:0005070(SH3/SH2 adaptor activity);GO:0002260(lymphocyte homeostasis);GO:0006954(inflammatory response);GO:0006955(immune response);GO:0007229(integrin-mediated signaling pathway);GO:0007265(Ras protein signal transduction);GO:0010467(gene expression);GO:0019722(calcium-mediated signaling);GO:0035556(intracellular signal transduction);GO:0045860(positive regulation of protein kinase activity);GO:0048872(homeostasis of number of cells);GO:0050863(regulation of T cell activation);GO:0001772(immunological synapse);GO:0005911(cell-cell junction);GO:0045121(membrane raft)","04014(Ras signaling pathway);04015(Rap1 signaling pathway);04064(NF-kappa B signaling pathway);04650(Natural killer cell mediated cytotoxicity);04660(T cell receptor signaling pathway);04658(Th1 and Th2 cell differentiation);04659(Th17 cell differentiation);04664(Fc epsilon RI signaling pathway);04666(Fc gamma R-mediated phagocytosis)","NA","NA","linker for activation of T-cells [Source:HGNC Symbol;Acc:HGNC:18874]",{"v":0.177857,"d":"0.18"},{"v":0.156677,"d":"0.16"},{"v":1.13518257306433,"d":"1.14"},{"v":0.182924346918914,"d":"0.18"},1,1,"up","no"]
[136077,0,"chr3","+",49007608,49015347,"ENST00000448293",6,3377,"MSTRG.10915","WDR6","GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0043560(insulin receptor substrate binding);GO:0043234(protein complex);GO:0010507(negative regulation of autophagy);GO:0003723(RNA binding);GO:0005737(cytoplasm);GO:0005515(protein binding);GO:0007049(cell cycle);GO:0008285(negative regulation of cell proliferation);GO:0008180(COP9 signalosome);GO:0007050(cell cycle arrest)","NA","NA","NA","WD repeat domain 6 [Source:HGNC Symbol;Acc:HGNC:12758]",0,{"v":0.002384,"d":"0.00"},"-inf","-inf",1,1,"down","no"]
[96457,0,"chr19","+",10544309,10552019,"ENST00000586863",5,529,"ENSG00000130734","ATG4D","GO:0006810(transport);GO:0005737(cytoplasm);GO:0015031(protein transport);GO:0016787(hydrolase activity);GO:0008233(peptidase activity);GO:0008234(cysteine-type peptidase activity);GO:0006508(proteolysis);GO:0006914(autophagy);GO:0005739(mitochondrion);GO:0006915(apoptotic process);GO:0005759(mitochondrial matrix);GO:0000045(autophagosome assembly);GO:0000422(mitophagy);GO:0005829(cytosol);GO:0044804(nucleophagy);GO:0004197(cysteine-type endopeptidase activity);GO:0006501(C-terminal protein lipidation);GO:0006612(protein targeting to membrane);GO:0051697(protein delipidation)","04140(Autophagy - animal);04136(Autophagy - other eukaryotes)","NA","NA","autophagy related 4D cysteine peptidase [Source:HGNC Symbol;Acc:HGNC:20789]",{"v":0.564684,"d":"0.56"},{"v":0.141722,"d":"0.14"},{"v":3.98444842720255,"d":"3.98"},{"v":1.99438002373507,"d":"1.99"},1,1,"up","no"]
[18673,0,"chr10","-",13684036,13707126,"ENST00000632314",5,1236,"MSTRG.1582","FRMD4A","GO:0005737(cytoplasm);GO:0005856(cytoskeleton);GO:0030674(protein binding, bridging);GO:0090162(establishment of epithelial cell polarity);GO:0005923(bicellular tight junction)","NA","NA","NA","FERM domain containing 4A [Source:HGNC Symbol;Acc:HGNC:25491]",{"v":0.042977,"d":"0.04"},0,"inf","inf",1,1,"up","no"]
[76647,0,"chr16","+",87892955,87893735,"ENST00000604757",2,467,"ENSG00000270385","AC133539.2","NA","NA","NA","NA","NA",{"v":0.019586,"d":"0.02"},0,"inf","inf",1,1,"up","no"]
[170909,0,"chr6","+",167827133,167952262,"ENST00000366809",28,4839,"ENSG00000130396","AFDN","GO:0007165(signal transduction);GO:0005886(plasma membrane);GO:0005911(cell-cell junction);GO:0030054(cell junction);GO:0016607(nuclear speck);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0007155(cell adhesion);GO:0005515(protein binding);GO:0045296(cadherin binding);GO:0043547(positive regulation of GTPase activity);GO:0005912(adherens junction);GO:0032880(regulation of protein localization);GO:0007267(cell-cell signaling);GO:0005913(cell-cell adherens junction);GO:0034332(adherens junction organization);GO:0008022(protein C-terminus binding);GO:0017016(Ras GTPase binding);GO:0090557(establishment of endothelial intestinal barrier);GO:0050839(cell adhesion molecule binding);GO:0021537(telencephalon development);GO:0021987(cerebral cortex development);GO:0034334(adherens junction maintenance);GO:0048854(brain morphogenesis);GO:0048872(homeostasis of number of cells);GO:0060019(radial glial cell differentiation);GO:0060563(neuroepithelial cell differentiation);GO:0070445(regulation of oligodendrocyte progenitor proliferation);GO:1902414(protein localization to cell junction);GO:0005737(cytoplasm);GO:0043296(apical junction complex);GO:0045177(apical part of cell)","04014(Ras signaling pathway);04015(Rap1 signaling pathway);04024(cAMP signaling pathway);04520(Adherens junction);04530(Tight junction);04670(Leukocyte transendothelial migration)","NA","NA","afadin, adherens junction formation factor [Source:HGNC Symbol;Acc:HGNC:7137]",0,0,1,0,1,1,"no","no"]
[97154,0,"chr19","-",12771395,12773253,"ENST00000588052",5,607,"MSTRG.7855","HOOK2","GO:0006810(transport);GO:0005737(cytoplasm);GO:0015031(protein transport);GO:0043231(intracellular membrane-bounded organelle);GO:0005829(cytosol);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0005874(microtubule);GO:0005813(centrosome);GO:0005815(microtubule organizing center);GO:0008333(endosome to lysosome transport);GO:0008017(microtubule binding);GO:0051959(dynein light intermediate chain binding);GO:0030705(cytoskeleton-dependent intracellular transport);GO:0031122(cytoplasmic microtubule organization);GO:0042802(identical protein binding);GO:0007040(lysosome organization);GO:0007032(endosome organization);GO:0006897(endocytosis);GO:0045022(early endosome to late endosome transport);GO:0030897(HOPS complex);GO:0070695(FHF complex)","NA","NA","NA","hook microtubule tethering protein 2 [Source:HGNC Symbol;Acc:HGNC:19885]",{"v":0.753909,"d":"0.75"},{"v":0.118306,"d":"0.12"},{"v":6.37253393741653,"d":"6.37"},{"v":2.67186715145064,"d":"2.67"},1,1,"up","no"]
[176579,0,"chr7","+",99558422,99571777,"ENST00000626122",4,705,"MSTRG.13792","ZNF655","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0005730(nucleolus);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0003674(molecular_function);GO:2000134(negative regulation of G1/S transition of mitotic cell cycle);GO:0005622(intracellular)","NA","NA","NA","zinc finger protein 655 [Source:HGNC Symbol;Acc:HGNC:30899]",{"v":0.047199,"d":"0.05"},0,"inf","inf",1,1,"up","no"]
[81124,0,"chr17","-",28328337,28335439,"ENST00000585313",6,852,"MSTRG.6546","IFT20","GO:0005737(cytoplasm);GO:0005794(Golgi apparatus);GO:0005856(cytoskeleton);GO:0042995(cell projection);GO:0005515(protein binding);GO:0035735(intraciliary transport involved in cilium assembly);GO:0060271(cilium assembly);GO:0005929(cilium);GO:0030992(intraciliary transport particle B);GO:0097542(ciliary tip);GO:0070062(extracellular exosome);GO:0030030(cell projection organization);GO:0005814(centriole);GO:1902017(regulation of cilium assembly);GO:0000139(Golgi membrane);GO:0017137(Rab GTPase binding);GO:0005813(centrosome);GO:0005801(cis-Golgi network);GO:2000785(regulation of autophagosome assembly);GO:0034067(protein localization to Golgi apparatus);GO:0031514(motile cilium);GO:0002046(opsin binding);GO:0001736(establishment of planar polarity);GO:0001822(kidney development);GO:0007224(smoothened signaling pathway);GO:0008542(visual learning);GO:0022008(neurogenesis);GO:0035845(photoreceptor cell outer segment organization);GO:0036372(opsin transport);GO:0042073(intraciliary transport);GO:0051642(centrosome localization);GO:0055007(cardiac muscle cell differentiation);GO:0060122(inner ear receptor stereocilium organization);GO:0060828(regulation of canonical Wnt signaling pathway);GO:0061351(neural precursor cell proliferation);GO:0061512(protein localization to cilium);GO:0090002(establishment of protein localization to plasma membrane);GO:0090102(cochlea development);GO:0001750(photoreceptor outer segment);GO:0005902(microvillus);GO:0032391(photoreceptor connecting cilium);GO:0032420(stereocilium);GO:0036064(ciliary basal body);GO:0044292(dendrite terminus);GO:0097546(ciliary base);GO:1902636(kinociliary basal body)","NA","NA","NA","intraflagellar transport 20 [Source:HGNC Symbol;Acc:HGNC:30989]",{"v":0.062507,"d":"0.06"},{"v":0.23828,"d":"0.24"},{"v":0.262325835151922,"d":"0.26"},{"v":-1.93056819651008,"d":"-1.93"},1,1,"down","no"]
[30319,0,"chr11","-",62722864,62723985,"ENST00000540127",2,439,"MSTRG.2472","HNRNPUL2","GO:0003723(RNA binding);GO:0005634(nucleus);GO:0016020(membrane);GO:0005654(nucleoplasm);GO:0008150(biological_process)","NA","NA","NA","heterogeneous nuclear ribonucleoprotein U like 2 [Source:HGNC Symbol;Acc:HGNC:25451]",{"v":0.366412,"d":"0.37"},{"v":0.291425,"d":"0.29"},{"v":1.25731148666038,"d":"1.26"},{"v":0.330342107666807,"d":"0.33"},1,1,"up","no"]
[71852,0,"chr16","-",30204722,30206162,"ENST00000549390",3,502,"MSTRG.5834","AC106782.1","NA","NA","NA","NA","NA",0,0,1,0,1,1,"no","no"]
[74149,0,"chr16","-",66725849,66732637,"ENST00000564833",6,727,"ENSG00000135720","DYNC1LI2","GO:0003777(microtubule motor activity);GO:0007018(microtubule-based movement);GO:0005868(cytoplasmic dynein complex);GO:0006810(transport);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0005856(cytoskeleton);GO:0005874(microtubule);GO:0003774(motor activity);GO:0005813(centrosome);GO:0030286(dynein complex);GO:0005829(cytosol);GO:0007062(sister chromatid cohesion);GO:0019886(antigen processing and presentation of exogenous peptide antigen via MHC class II);GO:0006888(ER to Golgi vesicle-mediated transport);GO:0045504(dynein heavy chain binding);GO:0000226(microtubule cytoskeleton organization);GO:0051642(centrosome localization)","04145(Phagosome);04962(Vasopressin-regulated water reabsorption);05132(Salmonella infection)","NA","NA","dynein cytoplasmic 1 light intermediate chain 2 [Source:HGNC Symbol;Acc:HGNC:2966]",{"v":0.119761,"d":"0.12"},{"v":0.054848,"d":"0.05"},{"v":2.1835071470245,"d":"2.18"},{"v":1.12664725333476,"d":"1.13"},1,1,"up","no"]
[76365,0,"chr16","+",84700002,84709322,"ENST00000564566",2,561,"MSTRG.6197","USP10","GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0016579(protein deubiquitination);GO:0016787(hydrolase activity);GO:0005515(protein binding);GO:0008233(peptidase activity);GO:0008234(cysteine-type peptidase activity);GO:0006508(proteolysis);GO:0006281(DNA repair);GO:0006974(cellular response to DNA damage stimulus);GO:0006511(ubiquitin-dependent protein catabolic process);GO:0036459(thiol-dependent ubiquitinyl hydrolase activity);GO:0006914(autophagy);GO:0005768(endosome);GO:0044325(ion channel binding);GO:0043234(protein complex);GO:0005769(early endosome);GO:0071347(cellular response to interleukin-1);GO:0004843(thiol-dependent ubiquitin-specific protease activity);GO:0010506(regulation of autophagy);GO:0043124(negative regulation of I-kappaB kinase/NF-kappaB signaling);GO:0019985(translesion synthesis);GO:0030330(DNA damage response, signal transduction by p53 class mediator);GO:0002039(p53 binding);GO:0004197(cysteine-type endopeptidase activity)","NA","NA","NA","ubiquitin specific peptidase 10 [Source:HGNC Symbol;Acc:HGNC:12608]",0,0,1,0,1,1,"no","no"]
[117471,0,"chr2","+",191846539,192036759,"ENST00000424116",3,500,"MSTRG.9312","AC098617.1","NA","NA","NA","NA","NA",0,{"v":0.113505,"d":"0.11"},"-inf","-inf",1,1,"down","no"]
[113469,0,"chr2","+",111120914,111146281,"ENST00000357757",6,947,"MSTRG.9041","BCL2L11","GO:0016020(membrane);GO:0005739(mitochondrion);GO:0005515(protein binding);GO:0006915(apoptotic process);GO:0005829(cytosol);GO:0008017(microtubule binding);GO:0012505(endomembrane system);GO:0043065(positive regulation of apoptotic process);GO:0032464(positive regulation of protein homooligomerization);GO:0090200(positive regulation of release of cytochrome c from mitochondria);GO:0005741(mitochondrial outer membrane);GO:0034976(response to endoplasmic reticulum stress);GO:1900740(positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway);GO:0001844(protein insertion into mitochondrial membrane involved in apoptotic signaling pathway);GO:0008630(intrinsic apoptotic signaling pathway in response to DNA damage);GO:1902237(positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway);GO:1903896(positive regulation of IRE1-mediated unfolded protein response);GO:2000271(positive regulation of fibroblast apoptotic process);GO:2001244(positive regulation of intrinsic apoptotic signaling pathway);GO:0046982(protein heterodimerization activity);GO:0070840(dynein complex binding);GO:0001701(in utero embryonic development);GO:0001776(leukocyte homeostasis);GO:0001782(B cell homeostasis);GO:0001783(B cell apoptotic process);GO:0001822(kidney development);GO:0002260(lymphocyte homeostasis);GO:0002262(myeloid cell homeostasis);GO:0007160(cell-matrix adhesion);GO:0007283(spermatogenesis);GO:0007420(brain development);GO:0008584(male gonad development);GO:0009791(post-embryonic development);GO:0010942(positive regulation of cell death);GO:0030879(mammary gland development);GO:0035148(tube formation);GO:0042475(odontogenesis of dentin-containing tooth);GO:0042981(regulation of apoptotic process);GO:0043029(T cell homeostasis);GO:0043280(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process);GO:0043525(positive regulation of neuron apoptotic process);GO:0043583(ear development);GO:0045787(positive regulation of cell cycle);GO:0046620(regulation of organ growth);GO:0048066(developmental pigmentation);GO:0048070(regulation of developmental pigmentation);GO:0048536(spleen development);GO:0048538(thymus development);GO:0048563(post-embryonic animal organ morphogenesis);GO:0060139(positive regulation of apoptotic process by virus);GO:0060154(cellular process regulating host cell cycle in response to virus);GO:0070242(thymocyte apoptotic process);GO:0097192(extrinsic apoptotic signaling pathway in absence of ligand);GO:1902110(positive regulation of mitochondrial membrane permeability involved in apoptotic process);GO:1902263(apoptotic process involved in embryonic digit morphogenesis);GO:0005737(cytoplasm);GO:0005868(cytoplasmic dynein complex);GO:0019898(extrinsic component of membrane);GO:0043231(intracellular membrane-bounded organelle);GO:0097136(Bcl-2 family protein complex)","04068(FoxO signaling pathway);04151(PI3K-Akt signaling pathway);04210(Apoptosis);04215(Apoptosis - multiple species);05200(Pathways in cancer);05206(MicroRNAs in cancer);05210(Colorectal cancer);04932(Non-alcoholic fatty liver disease (NAFLD));01521(EGFR tyrosine kinase inhibitor resistance)","K16341","NA","BCL2 like 11 [Source:HGNC Symbol;Acc:HGNC:994]",0,{"v":0.028979,"d":"0.03"},"-inf","-inf",1,1,"down","no"]
[11793,0,"chr1","+",155610620,155614931,"ENST00000483734",13,2490,"MSTRG.1061","MSTO1","GO:0016020(membrane);GO:0003924(GTPase activity);GO:0005739(mitochondrion);GO:0005741(mitochondrial outer membrane);GO:0003674(molecular_function);GO:0005737(cytoplasm);GO:0007005(mitochondrion organization);GO:0048311(mitochondrion distribution)","NA","NA","NA","misato 1, mitochondrial distribution and morphology regulator [Source:HGNC Symbol;Acc:HGNC:29678]",0,0,1,0,1,1,"no","no"]
[21944,0,"chr10","-",86467053,86472287,"ENST00000489996",3,646,"MSTRG.1839","WAPL","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0051301(cell division);GO:0005694(chromosome);GO:0005515(protein binding);GO:0007049(cell cycle);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0016032(viral process);GO:0007062(sister chromatid cohesion);GO:0000785(chromatin);GO:0071168(protein localization to chromatin);GO:0000775(chromosome, centromeric region);GO:0008278(cohesin complex);GO:0008156(negative regulation of DNA replication);GO:0007064(mitotic sister chromatid cohesion);GO:0045875(negative regulation of sister chromatid cohesion);GO:0000278(mitotic cell cycle);GO:0009636(response to toxic substance);GO:0035562(negative regulation of chromatin binding);GO:0045132(meiotic chromosome segregation);GO:0048146(positive regulation of fibroblast proliferation);GO:0051983(regulation of chromosome segregation);GO:0060623(regulation of chromosome condensation);GO:0071922(regulation of cohesin loading);GO:0000795(synaptonemal complex)","NA","NA","NA","WAPL cohesin release factor [Source:HGNC Symbol;Acc:HGNC:23293]",0,{"v":0.205115,"d":"0.21"},"-inf","-inf",1,1,"down","no"]
[68086,0,"chr16","-",1962061,1964813,"ENST00000533161",5,1186,"MSTRG.5529","RPS2","GO:0003723(RNA binding);GO:0005634(nucleus);GO:0016020(membrane);GO:0006412(translation);GO:0030529(intracellular ribonucleoprotein complex);GO:0003735(structural constituent of ribosome);GO:0005840(ribosome);GO:0015935(small ribosomal subunit);GO:0005515(protein binding);GO:0022627(cytosolic small ribosomal subunit);GO:0005654(nucleoplasm);GO:0005925(focal adhesion);GO:0003729(mRNA binding);GO:0005829(cytosol);GO:0045296(cadherin binding);GO:0070062(extracellular exosome);GO:0019899(enzyme binding);GO:0006413(translational initiation);GO:0006364(rRNA processing);GO:0000184(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay);GO:0019083(viral transcription);GO:0006479(protein methylation);GO:0006614(SRP-dependent cotranslational protein targeting to membrane);GO:0017134(fibroblast growth factor binding);GO:0051347(positive regulation of transferase activity)","03010(Ribosome)","NA","NA","ribosomal protein S2 [Source:HGNC Symbol;Acc:HGNC:10404]",{"v":4.033742,"d":"4.03"},{"v":3.506286,"d":"3.51"},{"v":1.15043153924124,"d":"1.15"},{"v":0.202175133117948,"d":"0.20"},1,1,"up","no"]
[200190,0,"chrX","-",135777130,135785298,"ENST00000487941",5,1161,"ENSG00000228836","CT45A5","NA","NA","NA","NA","cancer/testis antigen family 45 member A5 [Source:HGNC Symbol;Acc:HGNC:33270]",{"v":0.011438,"d":"0.01"},{"v":0.037943,"d":"0.04"},{"v":0.301452178267401,"d":"0.30"},{"v":-1.72999894068427,"d":"-1.73"},1,1,"down","no"]
[114988,0,"chr2","+",144518406,144520085,"ENST00000595109",3,855,"MSTRG.9165","ZEB2-AS1","NA","NA","NA","NA","ZEB2 antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:37149]",0,0,1,0,1,1,"no","no"]
[22315,0,"chr10","-",93685253,93687941,"ENST00000482719",2,645,"MSTRG.1871","FRA10AC1","GO:0005634(nucleus);GO:0005515(protein binding)","NA","NA","NA","FRA10A associated CGG repeat 1 [Source:HGNC Symbol;Acc:HGNC:1162]",{"v":0.01001,"d":"0.01"},{"v":0.340183,"d":"0.34"},{"v":0.0294253387147506,"d":"0.03"},{"v":-5.08679716756866,"d":"-5.09"},1,1,"down","no"]
[27951,0,"chr11","+",34053451,34076415,"ENST00000526494",4,399,"MSTRG.2318","CAPRIN1","GO:0003723(RNA binding);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005829(cytosol);GO:0042995(cell projection);GO:0030154(cell differentiation);GO:0030425(dendrite);GO:0000932(P-body);GO:0005887(integral component of plasma membrane);GO:0017148(negative regulation of translation);GO:0010494(cytoplasmic stress granule);GO:0005515(protein binding);GO:0050775(positive regulation of dendrite morphogenesis);GO:0061003(positive regulation of dendritic spine morphogenesis)","NA","NA","NA","cell cycle associated protein 1 [Source:HGNC Symbol;Acc:HGNC:6743]",0,0,1,0,1,1,"no","no"]
[1900,0,"chr1","-",15720312,15732452,"ENST00000623689",4,684,"MSTRG.178","AL450998.3","NA","NA","NA","NA","NA",0,0,1,0,1,1,"no","no"]
[83102,0,"chr17","+",40318285,40357643,"ENST00000425707",7,3041,"MSTRG.6796","RARA","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0005829(cytosol);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0031490(chromatin DNA binding);GO:0043565(sequence-specific DNA binding);GO:0015629(actin cytoskeleton);GO:0005515(protein binding);GO:0003707(steroid hormone receptor activity);GO:0043401(steroid hormone mediated signaling pathway);GO:0003713(transcription coactivator activity);GO:0045893(positive regulation of transcription, DNA-templated);GO:0003714(transcription corepressor activity);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0005654(nucleoplasm);GO:0003708(retinoic acid receptor activity);GO:0048384(retinoic acid receptor signaling pathway);GO:0005102(receptor binding);GO:0008284(positive regulation of cell proliferation);GO:0009986(cell surface);GO:0019899(enzyme binding);GO:0019904(protein domain specific binding);GO:0032689(negative regulation of interferon-gamma production);GO:0032720(negative regulation of tumor necrosis factor production);GO:0008134(transcription factor binding);GO:0045892(negative regulation of transcription, DNA-templated);GO:0000790(nuclear chromatin);GO:0046982(protein heterodimerization activity);GO:0006367(transcription initiation from RNA polymerase II promoter);GO:0006468(protein phosphorylation);GO:0071300(cellular response to retinoic acid);GO:0043277(apoptotic cell clearance);GO:0032526(response to retinoic acid);GO:0045787(positive regulation of cell cycle);GO:0071391(cellular response to estrogen stimulus);GO:0001972(retinoic acid binding);GO:0051018(protein kinase A binding);GO:0007165(signal transduction);GO:0043422(protein kinase B binding);GO:0000900(translation repressor activity, nucleic acid binding);GO:0000975(regulatory region DNA binding);GO:0000977(RNA polymerase II regulatory region sequence-specific DNA binding);GO:0001012(RNA polymerase II regulatory region DNA binding);GO:0004879(RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding);GO:0008144(drug binding);GO:0042826(histone deacetylase binding);GO:0044212(transcription regulatory region DNA binding);GO:0044323(retinoic acid-responsive element binding);GO:0048027(mRNA 5'-UTR binding);GO:0051393(alpha-actinin binding);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0001657(ureteric bud development);GO:0001843(neural tube closure);GO:0001889(liver development);GO:0002068(glandular epithelial cell development);GO:0003148(outflow tract septum morphogenesis);GO:0003417(growth plate cartilage development);GO:0007281(germ cell development);GO:0007283(spermatogenesis);GO:0007565(female pregnancy);GO:0008285(negative regulation of cell proliferation);GO:0008584(male gonad development);GO:0010628(positive regulation of gene expression);GO:0010629(negative regulation of gene expression);GO:0017148(negative regulation of translation);GO:0021766(hippocampus development);GO:0030850(prostate gland development);GO:0030852(regulation of granulocyte differentiation);GO:0030853(negative regulation of granulocyte differentiation);GO:0031076(embryonic camera-type eye development);GO:0031641(regulation of myelination);GO:0032355(response to estradiol);GO:0032736(positive regulation of interleukin-13 production);GO:0032753(positive regulation of interleukin-4 production);GO:0032754(positive regulation of interleukin-5 production);GO:0033189(response to vitamin A);GO:0034097(response to cytokine);GO:0035264(multicellular organism growth);GO:0042981(regulation of apoptotic process);GO:0043066(negative regulation of apoptotic process);GO:0045471(response to ethanol);GO:0045596(negative regulation of cell differentiation);GO:0045630(positive regulation of T-helper 2 cell differentiation);GO:0045666(positive regulation of neuron differentiation);GO:0045947(negative regulation of translational initiation);GO:0048167(regulation of synaptic plasticity);GO:0051099(positive regulation of binding);GO:0055012(ventricular cardiac muscle cell differentiation);GO:0060010(Sertoli cell fate commitment);GO:0060173(limb development);GO:0060324(face development);GO:0060348(bone development);GO:0060534(trachea cartilage development);GO:0060591(chondroblast differentiation);GO:0061037(negative regulation of cartilage development);GO:0071222(cellular response to lipopolysaccharide);GO:0030425(dendrite);GO:0043005(neuron projection);GO:0043025(neuronal cell body);GO:0048471(perinuclear region of cytoplasm)","04659(Th17 cell differentiation);05200(Pathways in cancer);05202(Transcriptional misregulation in cancers);05221(Acute myeloid leukemia)","K08527","NA","retinoic acid receptor alpha [Source:HGNC Symbol;Acc:HGNC:9864]",{"v":0.344003,"d":"0.34"},0,"inf","inf",1,1,"up","no"]
[159888,0,"chr5","+",149064273,149089452,"ENST00000512007",2,245,"ENSG00000250072","AC091940.1","NA","NA","NA","NA","NA",{"v":0.130622,"d":"0.13"},0,"inf","inf",1,1,"up","no"]
[61037,0,"chr15","+",40002391,40035591,"ENST00000558557",17,2449,"MSTRG.4893","EIF2AK4","GO:0003723(RNA binding);GO:0005737(cytoplasm);GO:0006446(regulation of translational initiation);GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0000077(DNA damage checkpoint);GO:0007049(cell cycle);GO:0007399(nervous system development);GO:0000049(tRNA binding);GO:0002376(immune system process);GO:0002250(adaptive immune response);GO:0051607(defense response to virus);GO:0006417(regulation of translation);GO:0007050(cell cycle arrest);GO:0016032(viral process);GO:0010998(regulation of translational initiation by eIF2 alpha phosphorylation);GO:0004694(eukaryotic translation initiation factor 2alpha kinase activity);GO:0007616(long-term memory);GO:0060259(regulation of feeding behavior);GO:0046777(protein autophosphorylation);GO:0007612(learning);GO:0045665(negative regulation of neuron differentiation);GO:0002230(positive regulation of defense response to virus by host);GO:0045947(negative regulation of translational initiation);GO:0034198(cellular response to amino acid starvation);GO:0005844(polysome);GO:0034644(cellular response to UV);GO:0022626(cytosolic ribosome);GO:0032057(negative regulation of translational initiation in response to stress);GO:0002286(T cell activation involved in immune response);GO:1990138(neuron projection extension);GO:0032792(negative regulation of CREB transcription factor activity);GO:1990253(cellular response to leucine starvation);GO:0070417(cellular response to cold);GO:0002821(positive regulation of adaptive immune response);GO:0044828(negative regulation by host of viral genome replication);GO:0036492(eiF2alpha phosphorylation in response to endoplasmic reticulum stress);GO:0019081(viral translation);GO:0039520(induction by virus of host autophagy);GO:0060733(regulation of eIF2 alpha phosphorylation by amino acid starvation);GO:0071264(positive regulation of translational initiation in response to starvation);GO:1900273(positive regulation of long-term synaptic potentiation)","04141(Protein processing in endoplasmic reticulum);04140(Autophagy - animal);05162(Measles);05164(Influenza A);05160(Hepatitis C);05168(Herpes simplex infection);05169(Epstein-Barr virus infection)","NA","NA","eukaryotic translation initiation factor 2 alpha kinase 4 [Source:HGNC Symbol;Acc:HGNC:19687]",0,0,1,0,1,1,"no","no"]
[133235,0,"chr3","+",9947404,9954787,"ENST00000431558",4,614,"ENSG00000230082","PRRT3-AS1","NA","NA","NA","NA","PRRT3 antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:41151]",{"v":0.160208,"d":"0.16"},{"v":0.139816,"d":"0.14"},{"v":1.14584882989071,"d":"1.15"},{"v":0.196416724066315,"d":"0.20"},1,1,"up","no"]
[77946,0,"chr17","-",4064799,4072827,"ENST00000570365",5,539,"MSTRG.6319","ZZEF1","GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0005509(calcium ion binding)","NA","NA","NA","zinc finger ZZ-type and EF-hand domain containing 1 [Source:HGNC Symbol;Acc:HGNC:29027]",{"v":0.488973,"d":"0.49"},0,"inf","inf",1,1,"up","no"]
[141683,0,"chr3","+",150423039,150423451,"ENST00000492828",2,312,"ENSG00000196428","TSC22D2","GO:0006355(regulation of transcription, DNA-templated);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0006970(response to osmotic stress)","NA","NA","NA","TSC22 domain family member 2 [Source:HGNC Symbol;Acc:HGNC:29095]",{"v":0.249284,"d":"0.25"},0,"inf","inf",1,1,"up","no"]
[119534,0,"chr2","+",219498915,219506987,"ENST00000341142",13,1524,"ENSG00000144591","GMPPA","GO:0005737(cytoplasm);GO:0009058(biosynthetic process);GO:0005515(protein binding);GO:0016740(transferase activity);GO:0016779(nucleotidyltransferase activity);GO:0070062(extracellular exosome)","00051(Fructose and mannose metabolism);00520(Amino sugar and nucleotide sugar metabolism)","NA","NA","GDP-mannose pyrophosphorylase A [Source:HGNC Symbol;Acc:HGNC:22923]",{"v":0.316726,"d":"0.32"},0,"inf","inf",1,1,"up","no"]
[179660,0,"chr7","+",143321474,143330895,"ENST00000455478",7,569,"ENSG00000188037","CLCN1","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0055085(transmembrane transport);GO:0005216(ion channel activity);GO:1903959(regulation of anion transmembrane transport);GO:0042803(protein homodimerization activity);GO:0005244(voltage-gated ion channel activity);GO:0006811(ion transport);GO:0034765(regulation of ion transmembrane transport);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0005254(chloride channel activity);GO:0006821(chloride transport);GO:0034707(chloride channel complex);GO:0005247(voltage-gated chloride channel activity);GO:0005887(integral component of plasma membrane);GO:0034220(ion transmembrane transport);GO:1902476(chloride transmembrane transport);GO:0006936(muscle contraction);GO:0019227(neuronal action potential propagation);GO:0042383(sarcolemma)","NA","NA","NA","chloride voltage-gated channel 1 [Source:HGNC Symbol;Acc:HGNC:2019]",0,0,1,0,1,1,"no","no"]
[10987,0,"chr1","-",151778633,151783049,"ENST00000484421",5,862,"MSTRG.971","TDRKH","GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005737(cytoplasm);GO:0005739(mitochondrion);GO:0030154(cell differentiation);GO:0031047(gene silencing by RNA);GO:0007283(spermatogenesis);GO:0034587(piRNA metabolic process);GO:0043046(DNA methylation involved in gamete generation);GO:0009566(fertilization);GO:0007140(male meiotic nuclear division);GO:0071547(piP-body);GO:0071546(pi-body)","NA","NA","NA","tudor and KH domain containing [Source:HGNC Symbol;Acc:HGNC:11713]",{"v":0.037985,"d":"0.04"},0,"inf","inf",1,1,"up","no"]
[95554,0,"chr19","-",6677835,6678330,"ENST00000601475",2,368,"MSTRG.7741","C3","GO:0005615(extracellular space);GO:0005576(extracellular region);GO:0006629(lipid metabolic process);GO:0010951(negative regulation of endopeptidase activity);GO:0006631(fatty acid metabolic process);GO:0005515(protein binding);GO:0006508(proteolysis);GO:0006954(inflammatory response);GO:0002376(immune system process);GO:0045087(innate immune response);GO:0004252(serine-type endopeptidase activity);GO:0006956(complement activation);GO:0030449(regulation of complement activation);GO:0050776(regulation of immune response);GO:0005886(plasma membrane);GO:0004866(endopeptidase inhibitor activity);GO:0070062(extracellular exosome);GO:0001934(positive regulation of protein phosphorylation);GO:0044267(cellular protein metabolic process);GO:0072562(blood microparticle);GO:0043687(post-translational protein modification);GO:0043312(neutrophil degranulation);GO:0007186(G-protein coupled receptor signaling pathway);GO:0006955(immune response);GO:0007165(signal transduction);GO:0006958(complement activation, classical pathway);GO:0034774(secretory granule lumen);GO:0005102(receptor binding);GO:0005788(endoplasmic reticulum lumen);GO:0035578(azurophil granule lumen);GO:0006957(complement activation, alternative pathway);GO:0031715(C5L2 anaphylatoxin chemotactic receptor binding);GO:0001798(positive regulation of type IIa hypersensitivity);GO:0001970(positive regulation of activation of membrane attack complex);GO:0006911(phagocytosis, engulfment);GO:0010575(positive regulation of vascular endothelial growth factor production);GO:0010828(positive regulation of glucose transport);GO:0010866(regulation of triglyceride biosynthetic process);GO:0010884(positive regulation of lipid storage);GO:0045745(positive regulation of G-protein coupled receptor protein signaling pathway);GO:0045766(positive regulation of angiogenesis);GO:0050766(positive regulation of phagocytosis);GO:0097242(amyloid-beta clearance);GO:2000427(positive regulation of apoptotic cell clearance);GO:0043234(protein complex)","04145(Phagosome);04610(Complement and coagulation cascades);05203(Viral carcinogenesis);05322(Systemic lupus erythematosus);05133(Pertussis);05134(Legionellosis);05150(Staphylococcus aureus infection);05152(Tuberculosis);05168(Herpes simplex infection);05167(Kaposi's sarcoma-associated herpesvirus infection);05140(Leishmaniasis);05142(Chagas disease (American trypanosomiasis))","NA","NA","complement C3 [Source:HGNC Symbol;Acc:HGNC:1318]",0,0,1,0,1,1,"no","no"]
[157136,0,"chr5","-",103106564,103120138,"ENST00000513603",3,567,"ENSG00000145723","GIN1","GO:0003676(nucleic acid binding);GO:0015074(DNA integration)","NA","NA","NA","gypsy retrotransposon integrase 1 [Source:HGNC Symbol;Acc:HGNC:25959]",{"v":0.000726,"d":"0.00"},{"v":0.059989,"d":"0.06"},{"v":0.0121022187401024,"d":"0.01"},{"v":-6.36858462393577,"d":"-6.37"},1,1,"down","no"]
[162044,0,"chr5","-",179840590,179844325,"ENST00000520900",3,702,"MSTRG.12610","MRNIP","GO:0005634(nucleus);GO:0006281(DNA repair);GO:0006974(cellular response to DNA damage stimulus);GO:0005654(nucleoplasm);GO:0005515(protein binding);GO:0003674(molecular_function);GO:0008150(biological_process);GO:0005575(cellular_component);GO:0003682(chromatin binding);GO:0007095(mitotic G2 DNA damage checkpoint);GO:0045860(positive regulation of protein kinase activity);GO:0071168(protein localization to chromatin);GO:0030870(Mre11 complex);GO:0010212(response to ionizing radiation);GO:1905168(positive regulation of double-strand break repair via homologous recombination);GO:2001032(regulation of double-strand break repair via nonhomologous end joining)","NA","NA","NA","MRN complex interacting protein [Source:HGNC Symbol;Acc:HGNC:30817]",{"v":0.105917,"d":"0.11"},{"v":0.06316,"d":"0.06"},{"v":1.67696326789107,"d":"1.68"},{"v":0.745851088537459,"d":"0.75"},1,1,"up","no"]
[154906,0,"chr5","-",55697846,55712291,"ENST00000506624",3,370,"ENSG00000177058","SLC38A9","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0006810(transport);GO:0043231(intracellular membrane-bounded organelle);GO:0005654(nucleoplasm);GO:0005765(lysosomal membrane);GO:0005515(protein binding);GO:0005764(lysosome);GO:0071230(cellular response to amino acid stimulus);GO:0005768(endosome);GO:0031902(late endosome membrane);GO:0006865(amino acid transport);GO:0005770(late endosome);GO:0015171(amino acid transmembrane transporter activity);GO:0032008(positive regulation of TOR signaling);GO:0007050(cell cycle arrest);GO:0016241(regulation of macroautophagy);GO:0071986(Ragulator complex);GO:0003333(amino acid transmembrane transport)","04150(mTOR signaling pathway)","NA","NA","solute carrier family 38 member 9 [Source:HGNC Symbol;Acc:HGNC:26907]",{"v":0.271561,"d":"0.27"},0,"inf","inf",1,1,"up","no"]
[180498,0,"chr7","-",155501298,155644186,"ENST00000637398",8,2744,"MSTRG.14153","AC009403.2","NA","NA","NA","NA","NA",{"v":0.059295,"d":"0.06"},{"v":0.009733,"d":"0.01"},{"v":6.0921606904346,"d":"6.09"},{"v":2.606953995705,"d":"2.61"},1,1,"up","no"]
[96884,0,"chr19","-",11796084,11798598,"ENST00000589227",1,2515,"ENSG00000267646","AC008543.5","NA","NA","NA","NA","NA",0,0,1,0,1,1,"no","no"]
[82808,0,"chr17","-",39261460,39402523,"ENST00000577399",15,1620,"MSTRG.6773","FBXL20","GO:0005737(cytoplasm);GO:0005515(protein binding);GO:0005829(cytosol);GO:0000209(protein polyubiquitination);GO:0043687(post-translational protein modification);GO:0004842(ubiquitin-protein transferase activity);GO:0001662(behavioral fear response)","NA","NA","NA","F-box and leucine rich repeat protein 20 [Source:HGNC Symbol;Acc:HGNC:24679]",{"v":0.314906,"d":"0.31"},{"v":0.127005,"d":"0.13"},{"v":2.47947718593756,"d":"2.48"},{"v":1.3100359509468,"d":"1.31"},1,1,"up","no"]
[31345,0,"chr11","-",65655857,65662960,"ENST00000529389",8,992,"MSTRG.2557","RELA","GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0006355(regulation of transcription, DNA-templated);GO:0006366(transcription from RNA polymerase II promoter);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0031490(chromatin DNA binding);GO:0042803(protein homodimerization activity);GO:0005515(protein binding);GO:0051092(positive regulation of NF-kappaB transcription factor activity);GO:0045893(positive regulation of transcription, DNA-templated);GO:0006954(inflammatory response);GO:0038095(Fc-epsilon receptor signaling pathway);GO:0042802(identical protein binding);GO:0071159(NF-kappaB complex);GO:0051607(defense response to virus);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:0001078(transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0005654(nucleoplasm);GO:0019901(protein kinase binding);GO:0002223(stimulatory C-type lectin receptor signaling pathway);GO:0050852(T cell receptor signaling pathway);GO:0003682(chromatin binding);GO:0071347(cellular response to interleukin-1);GO:0071356(cellular response to tumor necrosis factor);GO:0016032(viral process);GO:0031625(ubiquitin protein ligase binding);GO:0043123(positive regulation of I-kappaB kinase/NF-kappaB signaling);GO:0008284(positive regulation of cell proliferation);GO:0047485(protein N-terminus binding);GO:0043066(negative regulation of apoptotic process);GO:0008134(transcription factor binding);GO:0044212(transcription regulatory region DNA binding);GO:0045892(negative regulation of transcription, DNA-templated);GO:0000790(nuclear chromatin);GO:0046982(protein heterodimerization activity);GO:0010033(response to organic substance);GO:0001077(transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0000977(RNA polymerase II regulatory region sequence-specific DNA binding);GO:1902895(positive regulation of pri-miRNA transcription from RNA polymerase II promoter);GO:0032481(positive regulation of type I interferon production);GO:0019221(cytokine-mediated signaling pathway);GO:0042826(histone deacetylase binding);GO:0051059(NF-kappaB binding);GO:0070555(response to interleukin-1);GO:0043620(regulation of DNA-templated transcription in response to stress);GO:1901223(negative regulation of NIK/NF-kappaB signaling);GO:0005667(transcription factor complex);GO:0071223(cellular response to lipoteichoic acid);GO:0000983(transcription factor activity, RNA polymerase II core promoter sequence-specific);GO:0006968(cellular defense response);GO:0050727(regulation of inflammatory response);GO:1901224(positive regulation of NIK/NF-kappaB signaling);GO:0070301(cellular response to hydrogen peroxide);GO:0042301(phosphate ion binding);GO:0003705(transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding);GO:2000630(positive regulation of miRNA metabolic process);GO:2001237(negative regulation of extrinsic apoptotic signaling pathway);GO:0010224(response to UV-B);GO:0031293(membrane protein intracellular domain proteolysis);GO:0000980(RNA polymerase II distal enhancer sequence-specific DNA binding);GO:0001205(transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding);GO:0071375(cellular response to peptide hormone stimulus);GO:0042805(actinin binding);GO:0071316(cellular response to nicotine);GO:0071354(cellular response to interleukin-6);GO:0070491(repressing transcription factor binding);GO:0050862(positive regulation of T cell receptor signaling pathway);GO:0033209(tumor necrosis factor-mediated signaling pathway);GO:0033613(activating transcription factor binding);GO:1901222(regulation of NIK/NF-kappaB signaling);GO:0033256(I-kappaB/NF-kappaB complex);GO:0001046(core promoter sequence-specific DNA binding);GO:0019899(enzyme binding);GO:0032403(protein complex binding);GO:0043565(sequence-specific DNA binding);GO:0071532(ankyrin repeat binding);GO:0001889(liver development);GO:0001942(hair follicle development);GO:0006117(acetaldehyde metabolic process);GO:0006952(defense response);GO:0007568(aging);GO:0009612(response to mechanical stimulus);GO:0009617(response to bacterium);GO:0009887(animal organ morphogenesis);GO:0010035(response to inorganic substance);GO:0014040(positive regulation of Schwann cell differentiation);GO:0014070(response to organic cyclic compound);GO:0032332(positive regulation of chondrocyte differentiation);GO:0032495(response to muramyl dipeptide);GO:0032496(response to lipopolysaccharide);GO:0032570(response to progesterone);GO:0032868(response to insulin);GO:0033234(negative regulation of protein sumoylation);GO:0033590(response to cobalamin);GO:0034097(response to cytokine);GO:0035729(cellular response to hepatocyte growth factor stimulus);GO:0035994(response to muscle stretch);GO:0042177(negative regulation of protein catabolic process);GO:0042493(response to drug);GO:0042542(response to hydrogen peroxide);GO:0043200(response to amino acid);GO:0043278(response to morphine);GO:0045084(positive regulation of interleukin-12 biosynthetic process);GO:0046627(negative regulation of insulin receptor signaling pathway);GO:0051591(response to cAMP);GO:0070431(nucleotide-binding oligomerization domain containing 2 signaling pathway);GO:0071222(cellular response to lipopolysaccharide);GO:0071224(cellular response to peptidoglycan);GO:1901522(positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus);GO:0035525(NF-kappaB p50/p65 complex);GO:0043234(protein complex)","04014(Ras signaling pathway);04010(MAPK signaling pathway);04064(NF-kappa B signaling pathway);04668(TNF signaling pathway);04066(HIF-1 signaling pathway);04071(Sphingolipid signaling pathway);04024(cAMP signaling pathway);04151(PI3K-Akt signaling pathway);04137(Mitophagy - animal);04210(Apoptosis);04218(Cellular senescence);04620(Toll-like receptor signaling pathway);04621(NOD-like receptor signaling pathway);04622(RIG-I-like receptor signaling pathway);04623(Cytosolic DNA-sensing pathway);04660(T cell receptor signaling pathway);04658(Th1 and Th2 cell differentiation);04659(Th17 cell differentiation);04657(IL-17 signaling pathway);04662(B cell receptor signaling pathway);04062(Chemokine signaling pathway);04920(Adipocytokine signaling pathway);04917(Prolactin signaling pathway);04926(Relaxin signaling pathway);04722(Neurotrophin signaling pathway);04380(Osteoclast differentiation);04211(Longevity regulating pathway - mammal);05200(Pathways in cancer);05202(Transcriptional misregulation in cancers);05203(Viral carcinogenesis);05212(Pancreatic cancer);05221(Acute myeloid leukemia);05220(Chronic myeloid leukemia);05215(Prostate cancer);05222(Small cell lung cancer);05321(Inflammatiory bowel disease (IBD));05030(Cocaine addiction);05418(Fluid shear stress and atherosclerosis);04932(Non-alcoholic fatty liver disease (NAFLD));04931(Insulin resistance);04933(AGE-RAGE signaling pathway in diabetic complications);05120(Epithelial cell signaling in Helicobacter pylori infection);05132(Salmonella infection);05131(Shigellosis);05133(Pertussis);05134(Legionellosis);05152(Tuberculosis);05166(HTLV-I infection);05162(Measles);05164(Influenza A);05161(Hepatitis B);05160(Hepatitis C);05168(Herpes simplex infection);05167(Kaposi's sarcoma-associated herpesvirus infection);05169(Epstein-Barr virus infection);05165(Human papillomavirus infection);05146(Amoebiasis);05145(Toxoplasmosis);05140(Leishmaniasis);05142(Chagas disease (American trypanosomiasis));01523(Antifolate resistance)","NA","NA","RELA proto-oncogene, NF-kB subunit [Source:HGNC Symbol;Acc:HGNC:9955]",0,0,1,0,1,1,"no","no"]
[2536,0,"chr1","-",22023990,22026048,"ENST00000455966",3,702,"MSTRG.223","LINC01635","NA","NA","NA","NA","long intergenic non-protein coding RNA 1635 [Source:HGNC Symbol;Acc:HGNC:52422]",0,{"v":0.053145,"d":"0.05"},"-inf","-inf",1,1,"down","no"]
[115387,0,"chr2","+",152098328,152109202,"ENST00000420365",2,507,"ENSG00000225214","AC079790.1","NA","NA","NA","NA","NA",0,0,1,0,1,1,"no","no"]
[164104,0,"chr6","+",30649906,30652749,"ENST00000487873",4,464,"MSTRG.12825","C6orf136","GO:0016020(membrane);GO:0016021(integral component of membrane)","NA","NA","NA","chromosome 6 open reading frame 136 [Source:HGNC Symbol;Acc:HGNC:21301]",{"v":0.028518,"d":"0.03"},{"v":0.051889,"d":"0.05"},{"v":0.549596253541213,"d":"0.55"},{"v":-0.86355592518538,"d":"-0.86"},1,1,"down","no"]
[46409,0,"chr12","-",109456222,109477289,"ENST00000541077",5,538,"MSTRG.3701","KCTD10","GO:0005634(nucleus);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0016567(protein ubiquitination);GO:0051260(protein homooligomerization);GO:0005515(protein binding);GO:0004842(ubiquitin-protein transferase activity);GO:0043161(proteasome-mediated ubiquitin-dependent protein catabolic process);GO:0031463(Cul3-RING ubiquitin ligase complex);GO:0005112(Notch binding);GO:0006511(ubiquitin-dependent protein catabolic process)","NA","NA","NA","potassium channel tetramerization domain containing 10 [Source:HGNC Symbol;Acc:HGNC:23236]",{"v":0.157901,"d":"0.16"},0,"inf","inf",1,1,"up","no"]
[14086,0,"chr1","+",181033972,181049697,"ENST00000486453",2,749,"ENSG00000153029","MR1","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005886(plasma membrane);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0002376(immune system process);GO:0045087(innate immune response);GO:0007165(signal transduction);GO:0002474(antigen processing and presentation of peptide antigen via MHC class I);GO:0042612(MHC class I protein complex);GO:0006955(immune response);GO:0032393(MHC class I receptor activity);GO:0002367(cytokine production involved in immune response);GO:0032611(interleukin-1 beta production);GO:0032620(interleukin-17 production);GO:0050829(defense response to Gram-negative bacterium)","NA","NA","NA","major histocompatibility complex, class I-related [Source:HGNC Symbol;Acc:HGNC:4975]",{"v":0.153275,"d":"0.15"},{"v":0.260713,"d":"0.26"},{"v":0.587907008856482,"d":"0.59"},{"v":-0.766340117497714,"d":"-0.77"},1,1,"down","no"]
[86869,0,"chr17","-",63894931,63896609,"ENST00000558284",2,1586,"ENSG00000136488","CSH1","GO:0046872(metal ion binding);GO:0005576(extracellular region);GO:0005179(hormone activity);GO:0005783(endoplasmic reticulum);GO:0031904(endosome lumen);GO:0060397(JAK-STAT cascade involved in growth hormone signaling pathway);GO:0031982(vesicle)","04630(Jak-STAT signaling pathway);04151(PI3K-Akt signaling pathway);04080(Neuroactive ligand-receptor interaction);04060(Cytokine-cytokine receptor interaction)","NA","NA","chorionic somatomammotropin hormone 1 [Source:HGNC Symbol;Acc:HGNC:2440]",0,0,1,0,1,1,"no","no"]
[121836,0,"chr20","-",5547341,5548381,"ENST00000462080",2,633,"MSTRG.9589","GPCPD1","GO:0005737(cytoplasm);GO:0030246(carbohydrate binding);GO:0016787(hydrolase activity);GO:0006629(lipid metabolic process);GO:0005829(cytosol);GO:0008081(phosphoric diester hydrolase activity);GO:0047389(glycerophosphocholine phosphodiesterase activity);GO:0046475(glycerophospholipid catabolic process);GO:2001070(starch binding);GO:0030643(cellular phosphate ion homeostasis);GO:0008889(glycerophosphodiester phosphodiesterase activity);GO:0007519(skeletal muscle tissue development)","00564(Glycerophospholipid metabolism);05231(Choline metabolism in cancer)","NA","NA","glycerophosphocholine phosphodiesterase 1 [Source:HGNC Symbol;Acc:HGNC:26957]",{"v":0.098658,"d":"0.10"},{"v":0.087491,"d":"0.09"},{"v":1.12763598541564,"d":"1.13"},{"v":0.173301423418547,"d":"0.17"},1,1,"up","no"]
[117288,0,"chr2","-",189771311,189774017,"ENST00000496543",2,723,"ENSG00000128699","ORMDL1","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0006672(ceramide metabolic process);GO:0090155(negative regulation of sphingolipid biosynthetic process);GO:0090156(cellular sphingolipid homeostasis);GO:1900060(negative regulation of ceramide biosynthetic process);GO:0035339(SPOTS complex)","NA","NA","NA","ORMDL sphingolipid biosynthesis regulator 1 [Source:HGNC Symbol;Acc:HGNC:16036]",{"v":0.015327,"d":"0.02"},{"v":0.125819,"d":"0.13"},{"v":0.121817849450401,"d":"0.12"},{"v":-3.03720255419756,"d":"-3.04"},1,1,"down","no"]
[22526,0,"chr10","+",96130679,96132909,"ENST00000484770",2,468,"ENSG00000177853","ZNF518A","GO:0005634(nucleus);GO:0003676(nucleic acid binding);GO:0046872(metal ion binding);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0000981(RNA polymerase II transcription factor activity, sequence-specific DNA binding)","NA","NA","NA","zinc finger protein 518A [Source:HGNC Symbol;Acc:HGNC:29009]",{"v":0.266557,"d":"0.27"},{"v":0.269479,"d":"0.27"},{"v":0.989156854522987,"d":"0.99"},{"v":-0.015728781891452,"d":"-0.02"},1,1,"down","no"]
[55097,0,"chr14","-",53036745,53153204,"ENST00000395606",13,12769,"ENSG00000100523","DDHD1","GO:0005737(cytoplasm);GO:0016787(hydrolase activity);GO:0046872(metal ion binding);GO:0006629(lipid metabolic process);GO:0016042(lipid catabolic process);GO:0005829(cytosol);GO:0006654(phosphatidic acid biosynthetic process);GO:0004620(phospholipase activity);GO:0090141(positive regulation of mitochondrial fission)","NA","NA","NA","DDHD domain containing 1 [Source:HGNC Symbol;Acc:HGNC:19714]",{"v":0.134175,"d":"0.13"},{"v":4e-06,"d":"0.00"},33543.75,{"v":15.0337563625478,"d":"15.03"},1,1,"up","no"]
[153150,0,"chr5","-",1318355,1326255,"ENST00000506641",9,792,"MSTRG.11959","CLPTM1L","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0006915(apoptotic process)","NA","NA","NA","CLPTM1 like [Source:HGNC Symbol;Acc:HGNC:24308]",{"v":0.058777,"d":"0.06"},0,"inf","inf",1,1,"up","no"]
[1510,0,"chr1","-",11056011,11060020,"ENST00000459997",5,731,"MSTRG.150","SRM","GO:0016740(transferase activity);GO:0003824(catalytic activity);GO:0042803(protein homodimerization activity);GO:0005515(protein binding);GO:0042802(identical protein binding);GO:0006595(polyamine metabolic process);GO:0005829(cytosol);GO:0006596(polyamine biosynthetic process);GO:0008295(spermidine biosynthetic process);GO:0004766(spermidine synthase activity);GO:1990830(cellular response to leukemia inhibitory factor)","00270(Cysteine and methionine metabolism);00330(Arginine and proline metabolism);00410(beta-Alanine metabolism);00480(Glutathione metabolism)","NA","NA","spermidine synthase [Source:HGNC Symbol;Acc:HGNC:11296]",0,0,1,0,1,1,"no","no"]
[149751,0,"chr4","-",102885049,103019650,"ENST00000503584",11,1399,"MSTRG.11778","SLC9B1","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0055085(transmembrane transport);GO:0005739(mitochondrion);GO:0006811(ion transport);GO:0005886(plasma membrane);GO:0042995(cell projection);GO:0015297(antiporter activity);GO:0015299(solute:proton antiporter activity);GO:0006812(cation transport);GO:0006814(sodium ion transport);GO:0035725(sodium ion transmembrane transport);GO:1902600(hydrogen ion transmembrane transport);GO:0034220(ion transmembrane transport);GO:0007338(single fertilization);GO:0030317(flagellated sperm motility);GO:0051453(regulation of intracellular pH);GO:0015385(sodium:proton antiporter activity);GO:0097228(sperm principal piece)","NA","NA","NA","solute carrier family 9 member B1 [Source:HGNC Symbol;Acc:HGNC:24244]",{"v":0.049605,"d":"0.05"},0,"inf","inf",1,1,"up","no"]
[22392,0,"chr10","+",94545816,94557196,"ENST00000630929",4,400,"ENSG00000119969","HELLS","GO:0005634(nucleus);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0016787(hydrolase activity);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0004386(helicase activity);GO:0051301(cell division);GO:0005515(protein binding);GO:0007049(cell cycle);GO:0007275(multicellular organism development);GO:0000775(chromosome, centromeric region);GO:0010216(maintenance of DNA methylation);GO:0046651(lymphocyte proliferation);GO:0005721(pericentric heterochromatin);GO:0031508(pericentric heterochromatin assembly);GO:0006346(methylation-dependent chromatin silencing);GO:0003682(chromatin binding);GO:0001655(urogenital system development);GO:0006306(DNA methylation);GO:0006342(chromatin silencing);GO:0043066(negative regulation of apoptotic process);GO:1990830(cellular response to leukemia inhibitory factor);GO:2001243(negative regulation of intrinsic apoptotic signaling pathway)","NA","NA","NA","helicase, lymphoid specific [Source:HGNC Symbol;Acc:HGNC:4861]",0,0,1,0,1,1,"no","no"]
[154360,0,"chr5","-",38940015,39074389,"ENST00000511516",38,7312,"MSTRG.12010","RICTOR","GO:0043085(positive regulation of catalytic activity);GO:0005515(protein binding);GO:0007275(multicellular organism development);GO:0031932(TORC2 complex);GO:0005829(cytosol);GO:0032956(regulation of actin cytoskeleton organization);GO:0031929(TOR signaling);GO:0038111(interleukin-7-mediated signaling pathway);GO:0048015(phosphatidylinositol-mediated signaling);GO:0009790(embryo development);GO:0032008(positive regulation of TOR signaling);GO:0031532(actin cytoskeleton reorganization);GO:0031295(T cell costimulation);GO:0019901(protein kinase binding);GO:0018105(peptidyl-serine phosphorylation);GO:0008047(enzyme activator activity);GO:0051896(regulation of protein kinase B signaling);GO:0030010(establishment of cell polarity);GO:0030950(establishment or maintenance of actin cytoskeleton polarity);GO:0042325(regulation of phosphorylation);GO:0051897(positive regulation of protein kinase B signaling);GO:0043022(ribosome binding);GO:0001932(regulation of protein phosphorylation);GO:0001938(positive regulation of endothelial cell proliferation);GO:0010468(regulation of gene expression);GO:0030838(positive regulation of actin filament polymerization);GO:0033135(regulation of peptidyl-serine phosphorylation);GO:0043087(regulation of GTPase activity);GO:0050727(regulation of inflammatory response);GO:0050731(positive regulation of peptidyl-tyrosine phosphorylation);GO:2000114(regulation of establishment of cell polarity)","04150(mTOR signaling pathway)","NA","NA","RPTOR independent companion of MTOR complex 2 [Source:HGNC Symbol;Acc:HGNC:28611]",{"v":0.156773,"d":"0.16"},{"v":0.015927,"d":"0.02"},{"v":9.8432222012934,"d":"9.84"},{"v":3.29913066240089,"d":"3.30"},1,1,"up","no"]
[107329,0,"chr2","+",10721649,10783435,"ENST00000272238",14,1565,"MSTRG.8513","ATP6V1C2","GO:0006810(transport);GO:0005765(lysosomal membrane);GO:0006811(ion transport);GO:0015078(hydrogen ion transmembrane transporter activity);GO:0015991(ATP hydrolysis coupled proton transport);GO:0015992(proton transport);GO:0033180(proton-transporting V-type ATPase, V1 domain);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0034220(ion transmembrane transport);GO:0008286(insulin receptor signaling pathway);GO:0016241(regulation of macroautophagy);GO:0033572(transferrin transport);GO:0090383(phagosome acidification);GO:0046983(protein dimerization activity);GO:0030177(positive regulation of Wnt signaling pathway);GO:0008553(hydrogen-exporting ATPase activity, phosphorylative mechanism);GO:0000221(vacuolar proton-transporting V-type ATPase, V1 domain);GO:0046961(proton-transporting ATPase activity, rotational mechanism)","00190(Oxidative phosphorylation);04150(mTOR signaling pathway);04145(Phagosome);04966(Collecting duct acid secretion);04721(Synaptic vesicle cycle);05323(Rheumatoid arthritis);05110(Vibrio cholerae infection);05120(Epithelial cell signaling in Helicobacter pylori infection)","K02148","NA","ATPase H+ transporting V1 subunit C2 [Source:HGNC Symbol;Acc:HGNC:18264]",{"v":2E-3,"d":"0.00"},{"v":0.015796,"d":"0.02"},{"v":0.126614332742466,"d":"0.13"},{"v":-2.98148736779826,"d":"-2.98"},1,1,"down","no"]
[177957,0,"chr7","+",114933869,115015765,"ENST00000498196",4,584,"MSTRG.13916","MDFIC","GO:0042308(negative regulation of protein import into nucleus);GO:0045892(negative regulation of transcription, DNA-templated);GO:0005634(nucleus);GO:0005730(nucleolus);GO:0005737(cytoplasm);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0045893(positive regulation of transcription, DNA-templated);GO:0005515(protein binding);GO:0016032(viral process);GO:0008134(transcription factor binding);GO:0030957(Tat protein binding);GO:0030332(cyclin binding);GO:0030111(regulation of Wnt signaling pathway);GO:0007257(activation of JUN kinase activity);GO:0050434(positive regulation of viral transcription)","NA","NA","NA","MyoD family inhibitor domain containing [Source:HGNC Symbol;Acc:HGNC:28870]",0,{"v":0.040541,"d":"0.04"},"-inf","-inf",1,1,"down","no"]
[198565,0,"chrX","-",81113701,81201942,"ENST00000358130",7,2126,"MSTRG.15381","HMGN5","GO:0005634(nucleus);GO:0003723(RNA binding);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0016569(covalent chromatin modification);GO:0003677(DNA binding);GO:0031492(nucleosomal DNA binding);GO:0000785(chromatin);GO:0045893(positive regulation of transcription, DNA-templated);GO:0003682(chromatin binding);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0010628(positive regulation of gene expression);GO:0043066(negative regulation of apoptotic process);GO:0008284(positive regulation of cell proliferation);GO:0006325(chromatin organization);GO:0006749(glutathione metabolic process);GO:0071157(negative regulation of cell cycle arrest);GO:0005654(nucleoplasm)","NA","NA","NA","high mobility group nucleosome binding domain 5 [Source:HGNC Symbol;Acc:HGNC:8013]",{"v":0.358353,"d":"0.36"},{"v":0.02689,"d":"0.03"},{"v":13.3266269988843,"d":"13.33"},{"v":3.73623977195675,"d":"3.74"},1,1,"up","no"]
[73736,0,"chr16","+",57985181,57988116,"ENST00000562915",3,2360,"ENSG00000159648","TEPP","GO:0005576(extracellular region)","NA","NA","NA","testis, prostate and placenta expressed [Source:HGNC Symbol;Acc:HGNC:33745]",{"v":0.090033,"d":"0.09"},{"v":0.021422,"d":"0.02"},{"v":4.20282886751937,"d":"4.20"},{"v":2.0713607134474,"d":"2.07"},1,1,"up","no"]
[154590,0,"chr5","-",43294413,43295857,"ENST00000514610",2,555,"ENSG00000112972","HMGCS1","GO:0005737(cytoplasm);GO:0016740(transferase activity);GO:0003824(catalytic activity);GO:0006629(lipid metabolic process);GO:0008152(metabolic process);GO:0004421(hydroxymethylglutaryl-CoA synthase activity);GO:0008144(drug binding);GO:0016853(isomerase activity);GO:0042803(protein homodimerization activity);GO:0043177(organic acid binding);GO:0001889(liver development);GO:0006694(steroid biosynthetic process);GO:0007420(brain development);GO:0008202(steroid metabolic process);GO:0008299(isoprenoid biosynthetic process);GO:0008584(male gonad development);GO:0009645(response to low light intensity stimulus);GO:0009725(response to hormone);GO:0010033(response to organic substance);GO:0010243(response to organonitrogen compound);GO:0014070(response to organic cyclic compound);GO:0014074(response to purine-containing compound);GO:0016126(sterol biosynthetic process);GO:0033197(response to vitamin E);GO:0034698(response to gonadotropin);GO:0042493(response to drug);GO:0046690(response to tellurium ion);GO:0055094(response to lipoprotein particle);GO:0070723(response to cholesterol);GO:0071372(cellular response to follicle-stimulating hormone stimulus);GO:0071397(cellular response to cholesterol);GO:0071407(cellular response to organic cyclic compound);GO:0005829(cytosol);GO:0008203(cholesterol metabolic process);GO:0006695(cholesterol biosynthetic process);GO:0045540(regulation of cholesterol biosynthetic process);GO:0019216(regulation of lipid metabolic process)","00650(Butanoate metabolism);00072(Synthesis and degradation of ketone bodies);00280(Valine, leucine and isoleucine degradation);00900(Terpenoid backbone biosynthesis)","NA","NA","3-hydroxy-3-methylglutaryl-CoA synthase 1 [Source:HGNC Symbol;Acc:HGNC:5007]",0,{"v":0.022464,"d":"0.02"},"-inf","-inf",1,1,"down","no"]
[83250,0,"chr17","-",41377650,41382403,"ENST00000394001",7,1751,"ENSG00000131737","KRT34","GO:0005198(structural molecule activity);GO:0005882(intermediate filament);GO:0005615(extracellular space);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0031424(keratinization);GO:0008544(epidermis development);GO:0070268(cornification)","NA","NA","NA","keratin 34 [Source:HGNC Symbol;Acc:HGNC:6452]",0,0,1,0,1,1,"no","no"]
[86471,0,"chr17","+",61069871,61070341,"ENST00000437246",1,471,"ENSG00000227694","RPL23AP74","NA","NA","NA","NA","ribosomal protein L23a pseudogene 74 [Source:HGNC Symbol;Acc:HGNC:36148]",{"v":0.481466,"d":"0.48"},{"v":0.036017,"d":"0.04"},{"v":13.3677430102452,"d":"13.37"},{"v":3.74068399840444,"d":"3.74"},1,1,"up","no"]
[174141,0,"chr7","-",55436056,55572413,"ENST00000462326",5,536,"MSTRG.13647","VOPP1","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0004871(signal transducer activity);GO:0030659(cytoplasmic vesicle membrane);GO:0031410(cytoplasmic vesicle);GO:0007165(signal transduction);GO:0031301(integral component of organelle membrane);GO:0005768(endosome)","NA","NA","NA","vesicular, overexpressed in cancer, prosurvival protein 1 [Source:HGNC Symbol;Acc:HGNC:34518]",{"v":0.097985,"d":"0.10"},{"v":0.56072,"d":"0.56"},{"v":0.174748537594521,"d":"0.17"},{"v":-2.51664771261403,"d":"-2.52"},1,1,"down","no"]
[8821,0,"chr1","+",109494079,109498855,"ENST00000496961",3,3424,"MSTRG.762","CYB561D1","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0046872(metal ion binding);GO:0055114(oxidation-reduction process)","NA","NA","NA","cytochrome b561 family member D1 [Source:HGNC Symbol;Acc:HGNC:26804]",{"v":0.026189,"d":"0.03"},{"v":0.066101,"d":"0.07"},{"v":0.396196729247667,"d":"0.40"},{"v":-1.3357111245985,"d":"-1.34"},1,1,"down","no"]
[88480,0,"chr17","-",76570910,76586956,"ENST00000588005",6,582,"MSTRG.7256","ST6GALNAC2","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016740(transferase activity);GO:0008373(sialyltransferase activity);GO:0016757(transferase activity, transferring glycosyl groups);GO:0006486(protein glycosylation);GO:0097503(sialylation);GO:0005794(Golgi apparatus);GO:0000139(Golgi membrane);GO:0016266(O-glycan processing);GO:0009311(oligosaccharide metabolic process);GO:0018279(protein N-linked glycosylation via asparagine);GO:0001665(alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity)","NA","NA","NA","ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 [Source:HGNC Symbol;Acc:HGNC:10867]",{"v":0.011182,"d":"0.01"},{"v":0.19673,"d":"0.20"},{"v":0.0568393229299039,"d":"0.06"},{"v":-4.13696682047707,"d":"-4.14"},1,1,"down","no"]
[155454,0,"chr5","+",69207731,69209801,"ENST00000510742",2,724,"ENSG00000153044","CENPH","GO:0005634(nucleus);GO:0005730(nucleolus);GO:0000776(kinetochore);GO:0051382(kinetochore assembly);GO:0005694(chromosome);GO:0005515(protein binding);GO:0000775(chromosome, centromeric region);GO:0000777(condensed chromosome kinetochore);GO:0043515(kinetochore binding);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0034080(CENP-A containing nucleosome assembly);GO:0007062(sister chromatid cohesion);GO:0051383(kinetochore organization)","NA","NA","NA","centromere protein H [Source:HGNC Symbol;Acc:HGNC:17268]",{"v":0.019484,"d":"0.02"},{"v":0.022638,"d":"0.02"},{"v":0.860676738227759,"d":"0.86"},{"v":-0.216456617690817,"d":"-0.22"},1,1,"down","no"]
[202162,0,"chrY","-",24763069,24813479,"ENST00000382365",19,3503,"ENSG00000187191","DAZ3","GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0007275(multicellular organism development);GO:0030154(cell differentiation);GO:0007283(spermatogenesis);GO:0003730(mRNA 3'-UTR binding);GO:0045948(positive regulation of translational initiation);GO:0008494(translation activator activity);GO:0070935(3'-UTR-mediated mRNA stabilization)","NA","NA","NA","deleted in azoospermia 3 [Source:HGNC Symbol;Acc:HGNC:15965]",0,0,1,0,1,1,"no","no"]
[103960,0,"chr19","+",49528626,49546962,"ENST00000598833",4,607,"MSTRG.8314","RCN3","GO:0046872(metal ion binding);GO:0005509(calcium ion binding);GO:0005783(endoplasmic reticulum);GO:0005515(protein binding);GO:0005788(endoplasmic reticulum lumen)","NA","NA","NA","reticulocalbin 3 [Source:HGNC Symbol;Acc:HGNC:21145]",0,0,1,0,1,1,"no","no"]
[27396,0,"chr11","+",20669571,21575681,"ENST00000298925",21,3329,"ENSG00000165973","NELL1","GO:0005509(calcium ion binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0048471(perinuclear region of cytoplasm);GO:0030154(cell differentiation);GO:0007399(nervous system development);GO:0030501(positive regulation of bone mineralization);GO:0005635(nuclear envelope);GO:0010468(regulation of gene expression);GO:0045669(positive regulation of osteoblast differentiation);GO:0033689(negative regulation of osteoblast proliferation);GO:1903363(negative regulation of cellular protein catabolic process)","NA","NA","NA","neural EGFL like 1 [Source:HGNC Symbol;Acc:HGNC:7750]",0,0,1,0,1,1,"no","no"]
[174547,0,"chr7","-",65508773,65508944,"ENST00000445949",1,172,"ENSG00000226767","AC114501.1","NA","NA","NA","NA","NA",0,{"v":0.147941,"d":"0.15"},"-inf","-inf",1,1,"down","no"]
[124009,0,"chr20","+",44935431,44939184,"ENST00000489068",5,442,"MSTRG.9764","PABPC1L","GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0070062(extracellular exosome);GO:0001556(oocyte maturation);GO:0006338(chromatin remodeling);GO:0006378(mRNA polyadenylation);GO:0048096(chromatin-mediated maintenance of transcription);GO:0051647(nucleus localization)","03013(RNA transport);03015(mRNA surveillance pathway);03018(RNA degradation)","NA","NA","poly(A) binding protein cytoplasmic 1 like [Source:HGNC Symbol;Acc:HGNC:15797]",0,{"v":0.100605,"d":"0.10"},"-inf","-inf",1,1,"down","no"]
[66508,0,"chr15","+",90903846,90911402,"ENST00000560192",12,2469,"MSTRG.5438","MAN2A2","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0046872(metal ion binding);GO:0030246(carbohydrate binding);GO:0016787(hydrolase activity);GO:0003824(catalytic activity);GO:0005975(carbohydrate metabolic process);GO:0008152(metabolic process);GO:0016798(hydrolase activity, acting on glycosyl bonds);GO:0004559(alpha-mannosidase activity);GO:0006013(mannose metabolic process);GO:0005794(Golgi apparatus);GO:0000139(Golgi membrane);GO:0006486(protein glycosylation);GO:0006517(protein deglycosylation);GO:0006491(N-glycan processing);GO:0004572(mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity);GO:0015923(mannosidase activity);GO:0016799(hydrolase activity, hydrolyzing N-glycosyl compounds)","00510(N-Glycan biosynthesis)","NA","NA","mannosidase alpha class 2A member 2 [Source:HGNC Symbol;Acc:HGNC:6825]",0,0,1,0,1,1,"no","no"]
[187035,0,"chr8","+",125363026,125367116,"ENST00000521460",2,645,"MSTRG.14557","NSMCE2","GO:0019789(SUMO transferase activity);GO:0000724(double-strand break repair via homologous recombination);GO:0016925(protein sumoylation);GO:0030915(Smc5-Smc6 complex);GO:0008270(zinc ion binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0051301(cell division);GO:0005694(chromosome);GO:0016874(ligase activity);GO:0005515(protein binding);GO:0006281(DNA repair);GO:0006310(DNA recombination);GO:0006974(cellular response to DNA damage stimulus);GO:0007049(cell cycle);GO:0016604(nuclear body);GO:0000781(chromosome, telomeric region);GO:0005654(nucleoplasm);GO:0016605(PML body);GO:0090398(cellular senescence);GO:0045842(positive regulation of mitotic metaphase/anaphase transition);GO:0034184(positive regulation of maintenance of mitotic sister chromatid cohesion);GO:0000722(telomere maintenance via recombination)","NA","NA","NA","NSE2/MMS21 homolog, SMC5-SMC6 complex SUMO ligase [Source:HGNC Symbol;Acc:HGNC:26513]",{"v":0.072732,"d":"0.07"},{"v":0.068761,"d":"0.07"},{"v":1.05775075987842,"d":"1.06"},{"v":0.0809997221134869,"d":"0.08"},1,1,"up","no"]
[57269,0,"chr14","+",77923232,77935012,"ENST00000555217",4,3560,"ENSG00000063761","ADCK1","GO:0000166(nucleotide binding);GO:0004674(protein serine/threonine kinase activity);GO:0005524(ATP binding);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0006468(protein phosphorylation);GO:0005576(extracellular region)","NA","NA","NA","aarF domain containing kinase 1 [Source:HGNC Symbol;Acc:HGNC:19038]",{"v":0.292756,"d":"0.29"},{"v":0.141066,"d":"0.14"},{"v":2.07531226518084,"d":"2.08"},{"v":1.05332843021054,"d":"1.05"},1,1,"up","no"]
[64722,0,"chr15","-",74836633,74838512,"ENST00000567472",5,841,"ENSG00000140474","ULK3","GO:0005737(cytoplasm);GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0006914(autophagy);GO:0005515(protein binding);GO:0097542(ciliary tip);GO:0046777(protein autophosphorylation);GO:0090398(cellular senescence);GO:0000407(pre-autophagosomal structure);GO:0045879(negative regulation of smoothened signaling pathway);GO:0045880(positive regulation of smoothened signaling pathway)","NA","NA","NA","unc-51 like kinase 3 [Source:HGNC Symbol;Acc:HGNC:19703]",0,0,1,0,1,1,"no","no"]
[134654,0,"chr3","+",36993534,37011840,"ENST00000454028",7,570,"MSTRG.10799","MLH1","GO:0005634(nucleus);GO:0016020(membrane);GO:0005524(ATP binding);GO:0005654(nucleoplasm);GO:0005515(protein binding);GO:0006281(DNA repair);GO:0006974(cellular response to DNA damage stimulus);GO:0007049(cell cycle);GO:0030983(mismatched DNA binding);GO:0006298(mismatch repair);GO:0016887(ATPase activity);GO:0000795(synaptonemal complex);GO:0003697(single-stranded DNA binding);GO:0032407(MutSalpha complex binding);GO:0003682(chromatin binding);GO:0032137(guanine/thymine mispair binding);GO:0000289(nuclear-transcribed mRNA poly(A) tail shortening);GO:0000712(resolution of meiotic recombination intermediates);GO:0002204(somatic recombination of immunoglobulin genes involved in immune response);GO:0006303(double-strand break repair via nonhomologous end joining);GO:0007060(male meiosis chromosome segregation);GO:0007129(synapsis);GO:0007131(reciprocal meiotic recombination);GO:0007140(male meiotic nuclear division);GO:0007283(spermatogenesis);GO:0008630(intrinsic apoptotic signaling pathway in response to DNA damage);GO:0016321(female meiosis chromosome segregation);GO:0016446(somatic hypermutation of immunoglobulin genes);GO:0016447(somatic recombination of immunoglobulin gene segments);GO:0043060(meiotic metaphase I plate congression);GO:0045132(meiotic chromosome segregation);GO:0045141(meiotic telomere clustering);GO:0045143(homologous chromosome segregation);GO:0045190(isotype switching);GO:0045950(negative regulation of mitotic recombination);GO:0048298(positive regulation of isotype switching to IgA isotypes);GO:0048304(positive regulation of isotype switching to IgG isotypes);GO:0048477(oogenesis);GO:0051257(meiotic spindle midzone assembly);GO:0051321(meiotic cell cycle);GO:0000793(condensed chromosome);GO:0000794(condensed nuclear chromosome);GO:0001673(male germ cell nucleus);GO:0005694(chromosome);GO:0005712(chiasma);GO:0005715(late recombination nodule);GO:0032389(MutLalpha complex)","03430(Mismatch repair);03460(Fanconi anemia pathway);05200(Pathways in cancer);05210(Colorectal cancer);05226(Gastric cancer);05213(Endometrial cancer);01524(Platinum drug resistance)","NA","NA","mutL homolog 1 [Source:HGNC Symbol;Acc:HGNC:7127]",0,{"v":0.055927,"d":"0.06"},"-inf","-inf",1,1,"down","no"]
[30972,0,"chr11","+",65040953,65044828,"ENST00000528109",2,1518,"ENSG00000168061","SAC3D1","NA","NA","NA","NA","SAC3 domain containing 1 [Source:HGNC Symbol;Acc:HGNC:30179]",{"v":0.104748,"d":"0.10"},{"v":0.290079,"d":"0.29"},{"v":0.361101630935021,"d":"0.36"},{"v":-1.46952315857601,"d":"-1.47"},1,1,"down","no"]
[104115,0,"chr19","-",49811036,49813309,"ENST00000531017",5,1022,"MSTRG.8331","FUZ","GO:0006810(transport);GO:0005737(cytoplasm);GO:0015031(protein transport);GO:0005856(cytoskeleton);GO:0042995(cell projection);GO:0005515(protein binding);GO:0007275(multicellular organism development);GO:0060271(cilium assembly);GO:0070062(extracellular exosome);GO:0030030(cell projection organization);GO:0008285(negative regulation of cell proliferation);GO:0090090(negative regulation of canonical Wnt signaling pathway);GO:0001843(neural tube closure);GO:0030336(negative regulation of cell migration);GO:0045724(positive regulation of cilium assembly);GO:0001942(hair follicle development);GO:0008589(regulation of smoothened signaling pathway);GO:0048704(embryonic skeletal system morphogenesis);GO:1905515(non-motile cilium assembly);GO:0001736(establishment of planar polarity);GO:0010172(embryonic body morphogenesis);GO:0090301(negative regulation of neural crest formation);GO:2000314(negative regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation)","NA","NA","NA","fuzzy planar cell polarity protein [Source:HGNC Symbol;Acc:HGNC:26219]",{"v":0.41565,"d":"0.42"},{"v":0.032433,"d":"0.03"},{"v":12.8156507261123,"d":"12.82"},{"v":3.67983482950597,"d":"3.68"},1,1,"up","no"]
[144430,0,"chr3","+",195708154,195709563,"ENST00000626220",2,932,"ENSG00000242086","LINC00969","NA","NA","NA","NA","long intergenic non-protein coding RNA 969 [Source:HGNC Symbol;Acc:HGNC:48729]",{"v":6.548E-3,"d":"0.01"},0,"inf","inf",1,1,"up","no"]
[89265,0,"chr17","-",81233994,81237598,"ENST00000571094",4,453,"MSTRG.7316","TEPSIN","GO:0005737(cytoplasm);GO:0016607(nuclear speck);GO:0005794(Golgi apparatus);GO:0031965(nuclear membrane);GO:0005829(cytosol);GO:0031410(cytoplasmic vesicle)","NA","NA","NA","TEPSIN, adaptor related protein complex 4 accessory protein [Source:HGNC Symbol;Acc:HGNC:26458]",{"v":0.052655,"d":"0.05"},{"v":0.40134,"d":"0.40"},{"v":0.131197986744406,"d":"0.13"},{"v":-2.93018251316419,"d":"-2.93"},1,1,"down","no"]
[29924,0,"chr11","-",61351097,61357347,"ENST00000542361",5,650,"MSTRG.2442","CYB561A3","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0046872(metal ion binding);GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0005765(lysosomal membrane);GO:0005515(protein binding);GO:0005764(lysosome);GO:0005768(endosome);GO:0031902(late endosome membrane)","NA","NA","NA","cytochrome b561 family member A3 [Source:HGNC Symbol;Acc:HGNC:23014]",{"v":5.7e-05,"d":"0.00"},0,"inf","inf",1,1,"up","no"]
[85030,0,"chr17","-",48180092,48185179,"ENST00000579336",3,678,"MSTRG.6962","SKAP1","GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0009967(positive regulation of signal transduction);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0045893(positive regulation of transcription, DNA-templated);GO:0002376(immune system process);GO:0002250(adaptive immune response);GO:0019901(protein kinase binding);GO:0042169(SH2 domain binding);GO:0019903(protein phosphatase binding);GO:0050852(T cell receptor signaling pathway);GO:0017124(SH3 domain binding);GO:0005070(SH3/SH2 adaptor activity);GO:0032403(protein complex binding);GO:0045785(positive regulation of cell adhesion);GO:0072659(protein localization to plasma membrane);GO:0005829(cytosol);GO:0005911(cell-cell junction);GO:0042101(T cell receptor complex)","04015(Rap1 signaling pathway)","NA","NA","src kinase associated phosphoprotein 1 [Source:HGNC Symbol;Acc:HGNC:15605]",0,{"v":0.046009,"d":"0.05"},"-inf","-inf",1,1,"down","no"]
[142566,0,"chr3","+",169985129,169992721,"ENST00000470355",4,370,"MSTRG.11331","SEC62","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0008565(protein transporter activity);GO:0015031(protein transport);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005829(cytosol);GO:0004872(receptor activity);GO:0036498(IRE1-mediated unfolded protein response);GO:0005791(rough endoplasmic reticulum);GO:0006613(cotranslational protein targeting to membrane);GO:0006620(posttranslational protein targeting to endoplasmic reticulum membrane)","03060(Protein export);04141(Protein processing in endoplasmic reticulum)","NA","NA","SEC62 homolog, preprotein translocation factor [Source:HGNC Symbol;Acc:HGNC:11846]",{"v":0.523954,"d":"0.52"},{"v":0.761933,"d":"0.76"},{"v":0.687664138447869,"d":"0.69"},{"v":-0.540223983600627,"d":"-0.54"},1,1,"down","no"]
[127803,0,"chr21","+",44627123,44628293,"ENST00000397911",1,1171,"ENSG00000221837","KRTAP10-9","GO:0005515(protein binding);GO:0005882(intermediate filament);GO:0045095(keratin filament);GO:0005829(cytosol);GO:0031424(keratinization)","NA","NA","NA","keratin associated protein 10-9 [Source:HGNC Symbol;Acc:HGNC:22971]",0,0,1,0,1,1,"no","no"]
[929,0,"chr1","+",3857473,3885429,"ENST00000477548",8,2923,"ENSG00000169598","DFFB","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005730(nucleolus);GO:0016787(hydrolase activity);GO:0005622(intracellular);GO:0000790(nuclear chromatin);GO:0005829(cytosol);GO:0006915(apoptotic process);GO:0005515(protein binding);GO:0004518(nuclease activity);GO:0005654(nucleoplasm);GO:0006309(apoptotic DNA fragmentation);GO:0019899(enzyme binding);GO:0019904(protein domain specific binding);GO:0051260(protein homooligomerization);GO:0042802(identical protein binding);GO:0004536(deoxyribonuclease activity);GO:0097718(disordered domain specific binding);GO:0006308(DNA catabolic process);GO:0030263(apoptotic chromosome condensation);GO:0003677(DNA binding)","04210(Apoptosis)","K02311","EC:3.-.-.-","DNA fragmentation factor subunit beta [Source:HGNC Symbol;Acc:HGNC:2773]",{"v":0.011731,"d":"0.01"},{"v":0.012498,"d":"0.01"},{"v":0.938630180828933,"d":"0.94"},{"v":-0.0913712451836619,"d":"-0.09"},1,1,"down","no"]
[80077,0,"chr17","-",17505563,17518157,"ENST00000484838",5,803,"ENSG00000133027","PEMT","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0008168(methyltransferase activity);GO:0016740(transferase activity);GO:0032259(methylation);GO:0006629(lipid metabolic process);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005739(mitochondrion);GO:0008654(phospholipid biosynthetic process);GO:0006644(phospholipid metabolic process);GO:0031966(mitochondrial membrane);GO:0008170(N-methyltransferase activity);GO:0000773(phosphatidyl-N-methylethanolamine N-methyltransferase activity);GO:0004608(phosphatidylethanolamine N-methyltransferase activity);GO:0080101(phosphatidyl-N-dimethylethanolamine N-methyltransferase activity);GO:0006656(phosphatidylcholine biosynthetic process);GO:0008283(cell proliferation);GO:1903955(positive regulation of protein targeting to mitochondrion);GO:0008429(phosphatidylethanolamine binding);GO:0008757(S-adenosylmethionine-dependent methyltransferase activity);GO:0006650(glycerophospholipid metabolic process);GO:0006686(sphingomyelin biosynthetic process);GO:0007584(response to nutrient);GO:0008285(negative regulation of cell proliferation);GO:0033273(response to vitamin);GO:0042493(response to drug);GO:0043200(response to amino acid);GO:0045471(response to ethanol);GO:0046498(S-adenosylhomocysteine metabolic process);GO:0046500(S-adenosylmethionine metabolic process);GO:0050747(positive regulation of lipoprotein metabolic process);GO:0031526(brush border membrane);GO:0042383(sarcolemma)","00564(Glycerophospholipid metabolism)","NA","NA","phosphatidylethanolamine N-methyltransferase [Source:HGNC Symbol;Acc:HGNC:8830]",{"v":4.6E-5,"d":"0.00"},{"v":0.032312,"d":"0.03"},{"v":1.42361970784848E-3,"d":"0.00"},{"v":-9.45622047464607,"d":"-9.46"},1,1,"down","no"]
[175233,0,"chr7","+",75882044,75888921,"ENST00000428119",3,1274,"MSTRG.13725","RHBDD2","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005794(Golgi apparatus);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0004252(serine-type endopeptidase activity);GO:0006508(proteolysis);GO:0000139(Golgi membrane);GO:0048471(perinuclear region of cytoplasm)","NA","NA","NA","rhomboid domain containing 2 [Source:HGNC Symbol;Acc:HGNC:23082]",{"v":0.304634,"d":"0.30"},{"v":0.104199,"d":"0.10"},{"v":2.92357892110289,"d":"2.92"},{"v":1.54773553694615,"d":"1.55"},1,1,"up","no"]
[84703,0,"chr17","+",46923163,46941728,"ENST00000640495",4,3395,"ENSG00000108433","GOSR2","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0006810(transport);GO:0005794(Golgi apparatus);GO:0005484(SNAP receptor activity);GO:0061025(membrane fusion);GO:0015031(protein transport);GO:0016192(vesicle-mediated transport);GO:0005829(cytosol);GO:0005515(protein binding);GO:0000139(Golgi membrane);GO:0031902(late endosome membrane);GO:0006891(intra-Golgi vesicle-mediated transport);GO:0005789(endoplasmic reticulum membrane);GO:0000149(SNARE binding);GO:0006623(protein targeting to vacuole);GO:0006888(ER to Golgi vesicle-mediated transport);GO:0006896(Golgi to vacuole transport);GO:0042147(retrograde transport, endosome to Golgi);GO:0048280(vesicle fusion with Golgi apparatus);GO:0012507(ER to Golgi transport vesicle membrane);GO:0031201(SNARE complex);GO:0048208(COPII vesicle coating);GO:0036498(IRE1-mediated unfolded protein response);GO:0033116(endoplasmic reticulum-Golgi intermediate compartment membrane)","04130(SNARE interactions in vesicular transport)","NA","NA","golgi SNAP receptor complex member 2 [Source:HGNC Symbol;Acc:HGNC:4431]",{"v":0.130961,"d":"0.13"},{"v":0.342179,"d":"0.34"},{"v":0.382726584623837,"d":"0.38"},{"v":-1.3856139791621,"d":"-1.39"},1,1,"down","no"]
[54911,0,"chr14","-",50792844,50830708,"ENST00000496749",4,569,"MSTRG.4381","NIN","GO:0005509(calcium ion binding);GO:0005813(centrosome);GO:0034454(microtubule anchoring at centrosome);GO:0005737(cytoplasm);GO:0000166(nucleotide binding);GO:0005634(nucleus);GO:0005730(nucleolus);GO:0005525(GTP binding);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0005874(microtubule);GO:0005815(microtubule organizing center);GO:0005814(centriole);GO:0097539(ciliary transition fiber);GO:0000922(spindle pole);GO:0000242(pericentriolar material);GO:0051642(centrosome localization);GO:0090222(centrosome-templated microtubule nucleation);GO:0036449(microtubule minus-end);GO:0097431(mitotic spindle pole)","NA","NA","NA","ninein [Source:HGNC Symbol;Acc:HGNC:14906]",{"v":0.070835,"d":"0.07"},{"v":0.110311,"d":"0.11"},{"v":0.642139043250446,"d":"0.64"},{"v":-0.639042374971953,"d":"-0.64"},1,1,"down","no"]
[76112,0,"chr16","+",81630193,81632038,"ENST00000624151",1,1846,"MSTRG.6170","AC092135.3","NA","NA","NA","NA","NA",{"v":0.350259,"d":"0.35"},0,"inf","inf",1,1,"up","no"]
[123344,0,"chr20","+",35699442,35700978,"ENST00000374072",3,350,"MSTRG.9713","ROMO1","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005743(mitochondrial inner membrane);GO:0005739(mitochondrion);GO:0042742(defense response to bacterium);GO:0003674(molecular_function);GO:0050829(defense response to Gram-negative bacterium);GO:2000379(positive regulation of reactive oxygen species metabolic process);GO:0050830(defense response to Gram-positive bacterium);GO:0061844(antimicrobial humoral immune response mediated by antimicrobial peptide);GO:0008284(positive regulation of cell proliferation);GO:0031640(killing of cells of other organism);GO:0051715(cytolysis in other organism);GO:0034614(cellular response to reactive oxygen species);GO:0001302(replicative cell aging)","NA","NA","NA","reactive oxygen species modulator 1 [Source:HGNC Symbol;Acc:HGNC:16185]",{"v":0.000503,"d":"0.00"},{"v":0.03659,"d":"0.04"},{"v":0.0137469253894507,"d":"0.01"},{"v":-6.18474720542092,"d":"-6.18"},1,1,"down","no"]
[184580,0,"chr8","+",69834153,69850417,"ENST00000533300",3,431,"ENSG00000246528","AC079089.1","NA","NA","NA","NA","NA",{"v":0.042724,"d":"0.04"},0,"inf","inf",1,1,"up","no"]
[12910,0,"chr1","-",161230345,161238203,"ENST00000506209",7,1441,"ENSG00000143257","NR1I3","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0005654(nucleoplasm);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0043565(sequence-specific DNA binding);GO:0005856(cytoskeleton);GO:0003707(steroid hormone receptor activity);GO:0030522(intracellular receptor signaling pathway);GO:0043401(steroid hormone mediated signaling pathway);GO:0001228(transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0004887(thyroid hormone receptor activity);GO:0003713(transcription coactivator activity);GO:0007165(signal transduction);GO:0006367(transcription initiation from RNA polymerase II promoter);GO:0000977(RNA polymerase II regulatory region sequence-specific DNA binding);GO:0004879(RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding);GO:0004882(androgen receptor activity);GO:0030521(androgen receptor signaling pathway);GO:0045892(negative regulation of transcription, DNA-templated);GO:0005829(cytosol)","NA","NA","NA","nuclear receptor subfamily 1 group I member 3 [Source:HGNC Symbol;Acc:HGNC:7969]",{"v":0.036863,"d":"0.04"},0,"inf","inf",1,1,"up","no"]
[106482,0,"chr19","-",58087637,58098210,"ENST00000600318",3,2004,"ENSG00000121413","ZSCAN18","GO:0005634(nucleus);GO:0003676(nucleic acid binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0046872(metal ion binding);GO:0003677(DNA binding);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0000981(RNA polymerase II transcription factor activity, sequence-specific DNA binding)","NA","NA","NA","zinc finger and SCAN domain containing 18 [Source:HGNC Symbol;Acc:HGNC:21037]",{"v":0.025709,"d":"0.03"},{"v":0.050123,"d":"0.05"},{"v":0.512918221175907,"d":"0.51"},{"v":-0.96319927160647,"d":"-0.96"},1,1,"down","no"]
[72233,0,"chr16","+",31402565,31404699,"ENST00000567545",2,1767,"ENSG00000260757","AC093520.1","NA","NA","NA","NA","NA",0,{"v":0.016913,"d":"0.02"},"-inf","-inf",1,1,"down","no"]
[93981,0,"chr19","+",751126,764318,"ENST00000215582",5,2871,"ENSG00000099812","MISP","GO:0005737(cytoplasm);GO:0043231(intracellular membrane-bounded organelle);GO:0003779(actin binding);GO:0051301(cell division);GO:0005886(plasma membrane);GO:0005925(focal adhesion);GO:0005856(cytoskeleton);GO:0007049(cell cycle);GO:0030054(cell junction);GO:0005938(cell cortex)","NA","NA","NA","mitotic spindle positioning [Source:HGNC Symbol;Acc:HGNC:27000]",0,0,1,0,1,1,"no","no"]
[145784,0,"chr4","-",7965310,8020825,"ENST00000512594",7,2756,"ENSG00000163995","ABLIM2","GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0003779(actin binding);GO:0006351(transcription, DNA-templated);GO:0030036(actin cytoskeleton organization);GO:0007010(cytoskeleton organization);GO:0015629(actin cytoskeleton)","04360(Axon guidance)","NA","NA","actin binding LIM protein family member 2 [Source:HGNC Symbol;Acc:HGNC:19195]",0,0,1,0,1,1,"no","no"]
[120450,0,"chr2","+",233760248,233773299,"ENST00000305208",5,2382,"ENSG00000241635","UGT1A1","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016740(transferase activity);GO:0016757(transferase activity, transferring glycosyl groups);GO:0008152(metabolic process);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0042803(protein homodimerization activity);GO:0016758(transferase activity, transferring hexosyl groups);GO:0043086(negative regulation of catalytic activity);GO:0015020(glucuronosyltransferase activity);GO:0043231(intracellular membrane-bounded organelle);GO:0046982(protein heterodimerization activity);GO:0004857(enzyme inhibitor activity);GO:0007586(digestion);GO:0001972(retinoic acid binding);GO:0042573(retinoic acid metabolic process);GO:0051552(flavone metabolic process);GO:0052695(cellular glucuronidation);GO:0052696(flavonoid glucuronidation);GO:0052697(xenobiotic glucuronidation);GO:0008210(estrogen metabolic process);GO:0008202(steroid metabolic process);GO:0017144(drug metabolic process);GO:0046483(heterocycle metabolic process);GO:0005496(steroid binding);GO:0042167(heme catabolic process);GO:0019899(enzyme binding);GO:0001889(liver development);GO:0006789(bilirubin conjugation);GO:0006953(acute-phase response);GO:0007584(response to nutrient);GO:0010033(response to organic substance);GO:0014070(response to organic cyclic compound);GO:0031100(animal organ regeneration);GO:0032496(response to lipopolysaccharide);GO:0032870(cellular response to hormone stimulus);GO:0042493(response to drug);GO:0042594(response to starvation);GO:0045471(response to ethanol);GO:0045939(negative regulation of steroid metabolic process);GO:0048545(response to steroid hormone);GO:0051384(response to glucocorticoid);GO:0070980(biphenyl catabolic process);GO:0071361(cellular response to ethanol);GO:0071385(cellular response to glucocorticoid stimulus);GO:0071392(cellular response to estradiol stimulus);GO:0071466(cellular response to xenobiotic stimulus);GO:0005887(integral component of plasma membrane);GO:0034663(endoplasmic reticulum chaperone complex);GO:0070069(cytochrome complex)","00040(Pentose and glucuronate interconversions);00053(Ascorbate and aldarate metabolism);00140(Steroid hormone biosynthesis);00830(Retinol metabolism);00860(Porphyrin and chlorophyll metabolism);00980(Metabolism of xenobiotics by cytochrome P450);00982(Drug metabolism - cytochrome P450);00983(Drug metabolism - other enzymes);05204(Chemical carcinogenesis)","K00699","EC:2.4.1.17","UDP glucuronosyltransferase family 1 member A1 [Source:HGNC Symbol;Acc:HGNC:12530]",{"v":0.05556,"d":"0.06"},{"v":0.088717,"d":"0.09"},{"v":0.626261032271154,"d":"0.63"},{"v":-0.675163981708949,"d":"-0.68"},1,1,"down","no"]
[31795,0,"chr11","+",66744618,66804194,"ENST00000524551",6,548,"ENSG00000173715","C11orf80","GO:0042138(meiotic DNA double-strand break formation);GO:0005694(chromosome);GO:0051321(meiotic cell cycle);GO:0007131(reciprocal meiotic recombination)","NA","NA","NA","chromosome 11 open reading frame 80 [Source:HGNC Symbol;Acc:HGNC:26197]",{"v":0.068843,"d":"0.07"},0,"inf","inf",1,1,"up","no"]
[172596,0,"chr7","+",27121917,27128760,"ENST00000517550",4,2022,"ENSG00000253552","HOXA-AS2","NA","NA","NA","NA","HOXA cluster antisense RNA 2 [Source:HGNC Symbol;Acc:HGNC:43745]",0,0,1,0,1,1,"no","no"]
[119629,0,"chr2","+",221944223,221944612,"ENST00000417147",1,390,"ENSG00000233868","AC009302.1","NA","NA","NA","NA","NA",{"v":0.442214,"d":"0.44"},{"v":0.466228,"d":"0.47"},{"v":0.948493012002711,"d":"0.95"},{"v":-0.0762909502291796,"d":"-0.08"},1,1,"down","no"]
[111355,0,"chr2","-",74528822,74529760,"ENST00000472800",3,663,"MSTRG.8842","AUP1","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0050790(regulation of catalytic activity);GO:0005515(protein binding);GO:0030970(retrograde protein transport, ER to cytosol);GO:0070062(extracellular exosome);GO:0030176(integral component of endoplasmic reticulum membrane);GO:0043130(ubiquitin binding);GO:0030433(ubiquitin-dependent ERAD pathway);GO:0097027(ubiquitin-protein transferase activator activity);GO:0000839(Hrd1p ubiquitin ligase ERAD-L complex)","NA","NA","NA","ancient ubiquitous protein 1 [Source:HGNC Symbol;Acc:HGNC:891]",{"v":0.863557,"d":"0.86"},{"v":0.829648,"d":"0.83"},{"v":1.04087155034424,"d":"1.04"},{"v":0.0577920425899785,"d":"0.06"},1,1,"up","no"]
[118306,0,"chr2","+",203706524,203734912,"ENST00000458610",4,705,"MSTRG.9378","CD28","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005515(protein binding);GO:0006955(immune response);GO:0045727(positive regulation of translation);GO:0005886(plasma membrane);GO:0046854(phosphatidylinositol phosphorylation);GO:0005887(integral component of plasma membrane);GO:0005829(cytosol);GO:0010628(positive regulation of gene expression);GO:0042102(positive regulation of T cell proliferation);GO:0042802(identical protein binding);GO:0010629(negative regulation of gene expression);GO:0032753(positive regulation of interleukin-4 production);GO:0009986(cell surface);GO:0046934(phosphatidylinositol-4,5-bisphosphate 3-kinase activity);GO:0014066(regulation of phosphatidylinositol 3-kinase signaling);GO:0038111(interleukin-7-mediated signaling pathway);GO:0048015(phosphatidylinositol-mediated signaling);GO:0045840(positive regulation of mitotic nuclear division);GO:0031295(T cell costimulation);GO:0045070(positive regulation of viral genome replication);GO:0050690(regulation of defense response to virus by virus);GO:0005070(SH3/SH2 adaptor activity);GO:0015026(coreceptor activity);GO:0002020(protease binding);GO:0009897(external side of plasma membrane);GO:0006959(humoral immune response);GO:0007166(cell surface receptor signaling pathway);GO:0045086(positive regulation of interleukin-2 biosynthetic process);GO:0032733(positive regulation of interleukin-10 production);GO:0042089(cytokine biosynthetic process);GO:0045066(regulatory T cell differentiation);GO:0098636(protein complex involved in cell adhesion);GO:0019901(protein kinase binding);GO:0002863(positive regulation of inflammatory response to antigenic stimulus);GO:0014068(positive regulation of phosphatidylinositol 3-kinase signaling);GO:0045060(negative thymic T cell selection);GO:0045589(regulation of regulatory T cell differentiation);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0046641(positive regulation of alpha-beta T cell proliferation);GO:0048304(positive regulation of isotype switching to IgG isotypes);GO:0050852(T cell receptor signaling pathway);GO:0051897(positive regulation of protein kinase B signaling);GO:0097190(apoptotic signaling pathway);GO:0001772(immunological synapse)","04514(Cell adhesion molecules (CAMs));04660(T cell receptor signaling pathway);04672(Intestinal immune network for IgA production);05322(Systemic lupus erythematosus);05323(Rheumatoid arthritis);05320(Autoimmune thyroid disease);05330(Allograft rejection);05332(Graft-versus-host disease);05416(Viral myocarditis);04940(Type I diabetes mellitus);05162(Measles)","K06470","NA","CD28 molecule [Source:HGNC Symbol;Acc:HGNC:1653]",0,{"v":0.571524,"d":"0.57"},"-inf","-inf",1,1,"down","no"]
[116980,0,"chr2","+",180967248,181060812,"ENST00000602303",5,654,"MSTRG.9282","UBE2E3","GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016740(transferase activity);GO:0016567(protein ubiquitination);GO:0005515(protein binding);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0040008(regulation of growth);GO:0004842(ubiquitin-protein transferase activity);GO:0070534(protein K63-linked ubiquitination);GO:0070936(protein K48-linked ubiquitination);GO:0070979(protein K11-linked ubiquitination);GO:0061631(ubiquitin conjugating enzyme activity)","04120(Ubiquitin mediated proteolysis)","NA","NA","ubiquitin conjugating enzyme E2 E3 [Source:HGNC Symbol;Acc:HGNC:12479]",{"v":0.000133,"d":"0.00"},{"v":0.000441,"d":"0.00"},{"v":0.301587301587302,"d":"0.30"},{"v":-1.72935241005633,"d":"-1.73"},1,1,"down","no"]
[47292,0,"chr12","+",119677355,119681619,"ENST00000542698",2,4019,"ENSG00000111725","PRKAB1","GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0007165(signal transduction);GO:0006468(protein phosphorylation);GO:0006629(lipid metabolic process);GO:0006631(fatty acid metabolic process);GO:0006633(fatty acid biosynthetic process);GO:0005515(protein binding);GO:0004679(AMP-activated protein kinase activity);GO:0019901(protein kinase binding);GO:0035878(nail development);GO:0045859(regulation of protein kinase activity);GO:0050790(regulation of catalytic activity);GO:0051291(protein heterooligomerization);GO:0005634(nucleus);GO:0031588(nucleotide-activated protein kinase complex);GO:0043234(protein complex);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0010628(positive regulation of gene expression);GO:1901796(regulation of signal transduction by p53 class mediator);GO:0004672(protein kinase activity);GO:0007050(cell cycle arrest);GO:0016241(regulation of macroautophagy);GO:0016236(macroautophagy)","04371(Apelin signaling pathway);04068(FoxO signaling pathway);04152(AMPK signaling pathway);04530(Tight junction);04910(Insulin signaling pathway);04922(Glucagon signaling pathway);04920(Adipocytokine signaling pathway);04921(Oxytocin signaling pathway);04211(Longevity regulating pathway - mammal);04213(Longevity regulating pathway - multiple species);04710(Circadian rhythm);05410(Hypertrophic cardiomyopathy (HCM));04932(Non-alcoholic fatty liver disease (NAFLD));04931(Insulin resistance)","NA","NA","protein kinase AMP-activated non-catalytic subunit beta 1 [Source:HGNC Symbol;Acc:HGNC:9378]",{"v":0.126,"d":"0.13"},{"v":0.162202,"d":"0.16"},{"v":0.776809163882073,"d":"0.78"},{"v":-0.364367874808372,"d":"-0.36"},1,1,"down","no"]
[162656,0,"chr6","+",7107821,7210871,"ENST00000471433",7,1021,"MSTRG.12653","RREB1","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016607(nuclear speck);GO:0046872(metal ion binding);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0001650(fibrillar center);GO:0045893(positive regulation of transcription, DNA-templated);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0070062(extracellular exosome);GO:0001228(transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0007275(multicellular organism development);GO:0006366(transcription from RNA polymerase II promoter);GO:0000977(RNA polymerase II regulatory region sequence-specific DNA binding);GO:0007265(Ras protein signal transduction);GO:0010634(positive regulation of epithelial cell migration);GO:0016604(nuclear body);GO:0000979(RNA polymerase II core promoter sequence-specific DNA binding);GO:1900026(positive regulation of substrate adhesion-dependent cell spreading);GO:2000394(positive regulation of lamellipodium morphogenesis);GO:0033601(positive regulation of mammary gland epithelial cell proliferation);GO:1903691(positive regulation of wound healing, spreading of epidermal cells);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0045892(negative regulation of transcription, DNA-templated)","NA","NA","NA","ras responsive element binding protein 1 [Source:HGNC Symbol;Acc:HGNC:10449]",{"v":2.134E-3,"d":"0.00"},0,"inf","inf",1,1,"up","no"]
[46629,0,"chr12","+",110614106,110649125,"ENST00000397656",16,2098,"MSTRG.3721","TCTN1","GO:0005737(cytoplasm);GO:0005856(cytoskeleton);GO:0042995(cell projection);GO:0005576(extracellular region);GO:0007275(multicellular organism development);GO:0060271(cilium assembly);GO:0005829(cytosol);GO:0030030(cell projection organization);GO:0097711(ciliary basal body docking);GO:0036038(MKS complex);GO:0001701(in utero embryonic development);GO:0001841(neural tube formation);GO:0008589(regulation of smoothened signaling pathway);GO:0021523(somatic motor neuron differentiation);GO:0021537(telencephalon development);GO:0021904(dorsal/ventral neural tube patterning);GO:0021956(central nervous system interneuron axonogenesis);GO:1904491(protein localization to ciliary transition zone);GO:0005615(extracellular space);GO:0016020(membrane);GO:0035869(ciliary transition zone)","NA","NA","NA","tectonic family member 1 [Source:HGNC Symbol;Acc:HGNC:26113]",{"v":0.188254,"d":"0.19"},0,"inf","inf",1,1,"up","no"]
[188658,0,"chr9","-",456211,460227,"ENST00000590240",4,1224,"MSTRG.14652","AL161725.1","NA","NA","NA","NA","NA",{"v":0.331159,"d":"0.33"},{"v":0.132715,"d":"0.13"},{"v":2.49526428813623,"d":"2.50"},{"v":1.31919262798362,"d":"1.32"},1,1,"up","no"]
[176858,0,"chr7","+",100336125,100338990,"ENST00000414292",3,517,"MSTRG.13823","STAG3L5P","NA","NA","NA","NA","stromal antigen 3-like 5 pseudogene [Source:HGNC Symbol;Acc:HGNC:48896]",{"v":0.811315,"d":"0.81"},0,"inf","inf",1,1,"up","no"]
[70098,0,"chr16","+",16333648,16347455,"ENST00000538085",5,664,"ENSG00000183889","AC138969.1","GO:0005654(nucleoplasm)","NA","NA","NA","nuclear pore complex-interacting protein family member A5 isoform 2  [Source:RefSeq peptide;Acc:NP_001338129]",{"v":0.959925,"d":"0.96"},{"v":0.378284,"d":"0.38"},{"v":2.53757758720961,"d":"2.54"},{"v":1.3434519338136,"d":"1.34"},1,1,"up","no"]
[12578,0,"chr1","+",160211287,160213717,"ENST00000488858",4,654,"MSTRG.1110","PEA15","GO:0006810(transport);GO:0005737(cytoplasm);GO:0005634(nucleus);GO:0005829(cytosol);GO:0042981(regulation of apoptotic process);GO:0000077(DNA damage checkpoint);GO:0005515(protein binding);GO:0006915(apoptotic process);GO:0008643(carbohydrate transport);GO:0005875(microtubule associated complex);GO:0000165(MAPK cascade);GO:0000187(activation of MAPK activity);GO:0046325(negative regulation of glucose import);GO:1902042(negative regulation of extrinsic apoptotic signaling pathway via death domain receptors);GO:0043278(response to morphine);GO:1902043(positive regulation of extrinsic apoptotic signaling pathway via death domain receptors)","NA","NA","NA","phosphoprotein enriched in astrocytes 15 [Source:HGNC Symbol;Acc:HGNC:8822]",{"v":0.0079,"d":"0.01"},{"v":0.00013,"d":"0.00"},{"v":60.7692307692308,"d":"60.77"},{"v":5.92526912492337,"d":"5.93"},1,1,"up","no"]
[13170,0,"chr1","+",164559823,164684965,"ENST00000498497",3,3101,"ENSG00000185630","PBX1","GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0006355(regulation of transcription, DNA-templated);GO:0005737(cytoplasm);GO:0006366(transcription from RNA polymerase II promoter);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0006694(steroid biosynthetic process);GO:0043565(sequence-specific DNA binding);GO:0005515(protein binding);GO:0007275(multicellular organism development);GO:0030154(cell differentiation);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:0001077(transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0046982(protein heterodimerization activity);GO:0001655(urogenital system development);GO:0001658(branching involved in ureteric bud morphogenesis);GO:0008284(positive regulation of cell proliferation);GO:0009887(animal organ morphogenesis);GO:0009952(anterior/posterior pattern specification);GO:0009954(proximal/distal pattern formation);GO:0010971(positive regulation of G2/M transition of mitotic cell cycle);GO:0030278(regulation of ossification);GO:0030325(adrenal gland development);GO:0030326(embryonic limb morphogenesis);GO:0035162(embryonic hemopoiesis);GO:0042127(regulation of cell proliferation);GO:0045665(negative regulation of neuron differentiation);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0048536(spleen development);GO:0048538(thymus development);GO:0048568(embryonic organ development);GO:0048706(embryonic skeletal system development);GO:0005667(transcription factor complex);GO:0007548(sex differentiation);GO:0000977(RNA polymerase II regulatory region sequence-specific DNA binding);GO:0090575(RNA polymerase II transcription factor complex);GO:0035019(somatic stem cell population maintenance)","04927(Cortisol synthesis and secretion);05202(Transcriptional misregulation in cancers)","NA","NA","PBX homeobox 1 [Source:HGNC Symbol;Acc:HGNC:8632]",{"v":0.112798,"d":"0.11"},0,"inf","inf",1,1,"up","no"]
[164800,0,"chr6","-",31969810,31971685,"ENST00000491327",5,1395,"MSTRG.12928","DXO","GO:0003723(RNA binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0005829(cytosol);GO:0016787(hydrolase activity);GO:0005886(plasma membrane);GO:0008152(metabolic process);GO:0004527(exonuclease activity);GO:0000287(magnesium ion binding);GO:0004518(nuclease activity);GO:0003729(mRNA binding);GO:0008409(5'-3' exonuclease activity);GO:0034353(RNA pyrophosphohydrolase activity);GO:0006402(mRNA catabolic process);GO:0050779(RNA destabilization);GO:0071028(nuclear mRNA surveillance);GO:0090305(nucleic acid phosphodiester bond hydrolysis)","NA","NA","NA","decapping exoribonuclease [Source:HGNC Symbol;Acc:HGNC:2992]",{"v":0.352204,"d":"0.35"},{"v":0.366783,"d":"0.37"},{"v":0.960251701960015,"d":"0.96"},{"v":-0.0585154790811946,"d":"-0.06"},1,1,"down","no"]
[98461,0,"chr19","+",17933023,17936992,"ENST00000602080",2,609,"MSTRG.7979","CCDC124","GO:0003723(RNA binding);GO:0005737(cytoplasm);GO:0051301(cell division);GO:0005856(cytoskeleton);GO:0007049(cell cycle);GO:0005815(microtubule organizing center);GO:0030496(midbody)","NA","NA","NA","coiled-coil domain containing 124 [Source:HGNC Symbol;Acc:HGNC:25171]",{"v":0.049007,"d":"0.05"},{"v":0.070424,"d":"0.07"},{"v":0.695884925593548,"d":"0.70"},{"v":-0.523079339102751,"d":"-0.52"},1,1,"down","no"]
[130033,0,"chr22","-",29328738,29367275,"ENST00000402502",20,2935,"MSTRG.10345","AP1B1","GO:0006810(transport);GO:0016020(membrane);GO:0008565(protein transporter activity);GO:0006886(intracellular protein transport);GO:0015031(protein transport);GO:0016192(vesicle-mediated transport);GO:0005794(Golgi apparatus);GO:0030117(membrane coat);GO:0043231(intracellular membrane-bounded organelle);GO:0005829(cytosol);GO:0030131(clathrin adaptor complex);GO:0005515(protein binding);GO:0031410(cytoplasmic vesicle);GO:0019886(antigen processing and presentation of exogenous peptide antigen via MHC class II);GO:0005215(transporter activity);GO:0032588(trans-Golgi network membrane);GO:0030665(clathrin-coated vesicle membrane);GO:0000139(Golgi membrane);GO:0005765(lysosomal membrane);GO:0050690(regulation of defense response to virus by virus);GO:0030659(cytoplasmic vesicle membrane);GO:0030669(clathrin-coated endocytic vesicle membrane);GO:0019901(protein kinase binding);GO:0007368(determination of left/right symmetry);GO:0007507(heart development)","04142(Lysosome)","NA","NA","adaptor related protein complex 1 beta 1 subunit [Source:HGNC Symbol;Acc:HGNC:554]",0,0,1,0,1,1,"no","no"]
[113709,0,"chr2","-",113218528,113241683,"ENST00000468980",5,525,"ENSG00000125618","PAX8","GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0006355(regulation of transcription, DNA-templated);GO:0006366(transcription from RNA polymerase II promoter);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0005515(protein binding);GO:0007275(multicellular organism development);GO:0030154(cell differentiation);GO:0045893(positive regulation of transcription, DNA-templated);GO:0038194(thyroid-stimulating hormone signaling pathway);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0042981(regulation of apoptotic process);GO:0044212(transcription regulatory region DNA binding);GO:0030878(thyroid gland development);GO:0009653(anatomical structure morphogenesis);GO:0001823(mesonephros development);GO:0042472(inner ear morphogenesis);GO:0001822(kidney development);GO:0000979(RNA polymerase II core promoter sequence-specific DNA binding);GO:0007417(central nervous system development);GO:0090190(positive regulation of branching involved in ureteric bud morphogenesis);GO:0001658(branching involved in ureteric bud morphogenesis);GO:2000611(positive regulation of thyroid hormone generation);GO:0003337(mesenchymal to epithelial transition involved in metanephros morphogenesis);GO:0004996(thyroid-stimulating hormone receptor activity);GO:0071371(cellular response to gonadotropin stimulus);GO:0072207(metanephric epithelium development);GO:0072284(metanephric S-shaped body morphogenesis);GO:0001655(urogenital system development);GO:0048793(pronephros development);GO:0072289(metanephric nephron tubule formation);GO:0039003(pronephric field specification);GO:0072108(positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis);GO:0072221(metanephric distal convoluted tubule development);GO:0072305(negative regulation of mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis);GO:0072307(regulation of metanephric nephron tubule epithelial cell differentiation);GO:1900212(negative regulation of mesenchymal cell apoptotic process involved in metanephros development);GO:1900215(negative regulation of apoptotic process involved in metanephric collecting duct development);GO:1900218(negative regulation of apoptotic process involved in metanephric nephron tubule development);GO:2000594(positive regulation of metanephric DCT cell differentiation);GO:0071599(otic vesicle development);GO:0072278(metanephric comma-shaped body morphogenesis);GO:2000612(regulation of thyroid-stimulating hormone secretion);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:0001077(transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0043565(sequence-specific DNA binding);GO:0001656(metanephros development);GO:0006790(sulfur compound metabolic process);GO:0010667(negative regulation of cardiac muscle cell apoptotic process);GO:0072050(S-shaped body morphogenesis);GO:0072073(kidney epithelium development);GO:0072164(mesonephric tubule development)","04918(Thyroid hormone synthesis);05200(Pathways in cancer);05202(Transcriptional misregulation in cancers);05216(Thyroid cancer)","NA","NA","paired box 8 [Source:HGNC Symbol;Acc:HGNC:8622]",0,{"v":0.022702,"d":"0.02"},"-inf","-inf",1,1,"down","no"]
[69076,0,"chr16","-",4461691,4476306,"ENST00000574733",6,1719,"MSTRG.5604","NMRAL1","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0048471(perinuclear region of cytoplasm);GO:0005829(cytosol);GO:0000050(urea cycle)","NA","NA","NA","NmrA like redox sensor 1 [Source:HGNC Symbol;Acc:HGNC:24987]",{"v":0.983068,"d":"0.98"},{"v":0.385583,"d":"0.39"},{"v":2.54956261038479,"d":"2.55"},{"v":1.35024976710259,"d":"1.35"},1,1,"up","no"]
[163115,0,"chr6","-",18225025,18264535,"ENST00000505224",12,1372,"MSTRG.12699","DEK","GO:0003723(RNA binding);GO:0005634(nucleus);GO:0016569(covalent chromatin modification);GO:0003677(DNA binding);GO:0003682(chromatin binding);GO:0005654(nucleoplasm);GO:0006338(chromatin remodeling);GO:0045815(positive regulation of gene expression, epigenetic);GO:0007165(signal transduction);GO:0042393(histone binding);GO:0006366(transcription from RNA polymerase II promoter);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0019079(viral genome replication);GO:2000779(regulation of double-strand break repair);GO:2001032(regulation of double-strand break repair via nonhomologous end joining);GO:0043292(contractile fiber)","NA","NA","NA","DEK proto-oncogene [Source:HGNC Symbol;Acc:HGNC:2768]",{"v":0.131313,"d":"0.13"},{"v":0.027768,"d":"0.03"},{"v":4.72893258426966,"d":"4.73"},{"v":2.24151457486125,"d":"2.24"},1,1,"up","no"]
[2515,0,"chr1","-",21851311,21854656,"ENST00000493940",4,584,"ENSG00000142798","HSPG2","GO:0005615(extracellular space);GO:0046872(metal ion binding);GO:0005509(calcium ion binding);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0005578(proteinaceous extracellular matrix);GO:0005925(focal adhesion);GO:0005604(basement membrane);GO:0005886(plasma membrane);GO:0070062(extracellular exosome);GO:0044267(cellular protein metabolic process);GO:0031012(extracellular matrix);GO:0008022(protein C-terminus binding);GO:0043202(lysosomal lumen);GO:0001523(retinoid metabolic process);GO:0006024(glycosaminoglycan biosynthetic process);GO:0006027(glycosaminoglycan catabolic process);GO:0030198(extracellular matrix organization);GO:0030203(glycosaminoglycan metabolic process);GO:0005796(Golgi lumen);GO:0001525(angiogenesis);GO:0022617(extracellular matrix disassembly);GO:0050750(low-density lipoprotein particle receptor binding);GO:0006898(receptor-mediated endocytosis);GO:0006629(lipid metabolic process);GO:0098797(plasma membrane protein complex)","04512(ECM-receptor interaction);05205(Proteoglycans in cancer);05161(Hepatitis B)","NA","NA","heparan sulfate proteoglycan 2 [Source:HGNC Symbol;Acc:HGNC:5273]",{"v":0.064376,"d":"0.06"},0,"inf","inf",1,1,"up","no"]
[177631,0,"chr7","+",107179626,107182536,"ENST00000479011",2,601,"MSTRG.13902","HBP1","GO:0003723(RNA binding);GO:0005634(nucleus);GO:0016607(nuclear speck);GO:0005654(nucleoplasm);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0016055(Wnt signaling pathway);GO:0007050(cell cycle arrest)","NA","NA","NA","HMG-box transcription factor 1 [Source:HGNC Symbol;Acc:HGNC:23200]",0,{"v":0.024779,"d":"0.02"},"-inf","-inf",1,1,"down","no"]
[55902,0,"chr14","-",64766399,64823127,"ENST00000389721",31,6705,"MSTRG.4477","SPTB","GO:0005737(cytoplasm);GO:0005794(Golgi apparatus);GO:0005829(cytosol);GO:0003779(actin binding);GO:0051693(actin filament capping);GO:0043547(positive regulation of GTPase activity);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0005200(structural constituent of cytoskeleton);GO:0007010(cytoskeleton organization);GO:0008091(spectrin);GO:0051015(actin filament binding);GO:0005938(cell cortex);GO:0000165(MAPK cascade);GO:0043234(protein complex);GO:0015629(actin cytoskeleton);GO:0007411(axon guidance);GO:0006888(ER to Golgi vesicle-mediated transport);GO:0005088(Ras guanyl-nucleotide exchange factor activity);GO:0030506(ankyrin binding);GO:0014731(spectrin-associated cytoskeleton);GO:0031235(intrinsic component of the cytoplasmic side of the plasma membrane)","NA","NA","NA","spectrin beta, erythrocytic [Source:HGNC Symbol;Acc:HGNC:11274]",0,{"v":1.317762,"d":"1.32"},"-inf","-inf",1,1,"down","no"]
[196980,0,"chrX","+",48597521,48598293,"ENST00000472440",2,430,"MSTRG.15274","WDR13","GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005886(plasma membrane);GO:0005815(microtubule organizing center);GO:1990841(promoter-specific chromatin binding);GO:1904691(negative regulation of type B pancreatic cell proliferation)","NA","NA","NA","WD repeat domain 13 [Source:HGNC Symbol;Acc:HGNC:14352]",{"v":0.109455,"d":"0.11"},0,"inf","inf",1,1,"up","no"]
[5174,0,"chr1","+",43967160,43967663,"ENST00000486876",2,415,"ENSG00000117408","IPO13","GO:0006810(transport);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0006886(intracellular protein transport);GO:0015031(protein transport);GO:0005515(protein binding);GO:0008536(Ran GTPase binding);GO:0008139(nuclear localization sequence binding);GO:0008565(protein transporter activity);GO:0031965(nuclear membrane);GO:0006606(protein import into nucleus)","NA","NA","NA","importin 13 [Source:HGNC Symbol;Acc:HGNC:16853]",{"v":0.111218,"d":"0.11"},{"v":0.113894,"d":"0.11"},{"v":0.97650446906773,"d":"0.98"},{"v":-0.0343014481259383,"d":"-0.03"},1,1,"down","no"]
[64012,0,"chr15","-",68787413,68817615,"ENST00000495764",3,504,"MSTRG.5235","ANP32A","GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0005783(endoplasmic reticulum);GO:0005515(protein binding);GO:0048471(perinuclear region of cytoplasm);GO:0005654(nucleoplasm);GO:0043488(regulation of mRNA stability);GO:0042981(regulation of apoptotic process);GO:0035556(intracellular signal transduction);GO:0042393(histone binding);GO:0006913(nucleocytoplasmic transport)","NA","NA","NA","acidic nuclear phosphoprotein 32 family member A [Source:HGNC Symbol;Acc:HGNC:13233]",{"v":0.287968,"d":"0.29"},{"v":0.98159,"d":"0.98"},{"v":0.293368921851282,"d":"0.29"},{"v":-1.7692120482313,"d":"-1.77"},1,1,"down","no"]
[128731,0,"chr22","-",20148427,20151065,"ENST00000439765",9,1475,"ENSG00000234409","CCDC188","GO:0016020(membrane);GO:0016021(integral component of membrane)","NA","NA","NA","coiled-coil domain containing 188 [Source:HGNC Symbol;Acc:HGNC:51899]",{"v":0.043843,"d":"0.04"},{"v":0.062784,"d":"0.06"},{"v":0.698314857288481,"d":"0.70"},{"v":-0.518050427179685,"d":"-0.52"},1,1,"down","no"]
[161824,0,"chr5","-",178694605,178729335,"ENST00000638723",8,1653,"ENSG00000169131","ZNF354A","GO:0003676(nucleic acid binding);GO:0006355(regulation of transcription, DNA-templated);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0005622(intracellular);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0005730(nucleolus);GO:0005829(cytosol);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0007605(sensory perception of sound);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0001666(response to hypoxia);GO:0001822(kidney development);GO:0007576(nucleolar fragmentation);GO:0051593(response to folic acid)","NA","NA","NA","zinc finger protein 354A [Source:HGNC Symbol;Acc:HGNC:11628]",{"v":0.047895,"d":"0.05"},0,"inf","inf",1,1,"up","no"]
[131556,0,"chr22","+",40346528,40366614,"ENST00000216194",13,1620,"MSTRG.10502","ADSL","GO:0003824(catalytic activity);GO:0016829(lyase activity);GO:0006164(purine nucleotide biosynthetic process);GO:0044208('de novo' AMP biosynthetic process);GO:0004018(N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity);GO:0070626((S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido)succinate AMP-lyase (fumarate-forming) activity);GO:0006189('de novo' IMP biosynthetic process);GO:0009152(purine ribonucleotide biosynthetic process);GO:0005829(cytosol);GO:0009168(purine ribonucleoside monophosphate biosynthetic process);GO:0051262(protein tetramerization);GO:0006167(AMP biosynthetic process);GO:0001666(response to hypoxia);GO:0006163(purine nucleotide metabolic process);GO:0007584(response to nutrient);GO:0009060(aerobic respiration);GO:0009156(ribonucleoside monophosphate biosynthetic process);GO:0014850(response to muscle activity);GO:0042594(response to starvation);GO:0005739(mitochondrion)","00230(Purine metabolism);00250(Alanine, aspartate and glutamate metabolism)","K01756","EC:4.3.2.2","adenylosuccinate lyase [Source:HGNC Symbol;Acc:HGNC:291]",{"v":0.051818,"d":"0.05"},{"v":0.084703,"d":"0.08"},{"v":0.61176109464836,"d":"0.61"},{"v":-0.70895973421976,"d":"-0.71"},1,1,"down","no"]
[192672,0,"chr9","-",112222245,112333625,"ENST00000374255",15,3413,"MSTRG.14903","PTBP3","GO:0005634(nucleus);GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0006397(mRNA processing);GO:0008380(RNA splicing);GO:0045595(regulation of cell differentiation);GO:0030154(cell differentiation);GO:0043249(erythrocyte maturation);GO:0009653(anatomical structure morphogenesis);GO:0033119(negative regulation of RNA splicing)","NA","NA","NA","polypyrimidine tract binding protein 3 [Source:HGNC Symbol;Acc:HGNC:10253]",{"v":0.245092,"d":"0.25"},{"v":0.132433,"d":"0.13"},{"v":1.85068676236286,"d":"1.85"},{"v":0.88806073279507,"d":"0.89"},1,1,"up","no"]
[185698,0,"chr8","+",94823376,94880450,"ENST00000343161",29,3434,"MSTRG.14463","INTS8","GO:0005634(nucleus);GO:0005515(protein binding);GO:0005654(nucleoplasm);GO:0042795(snRNA transcription from RNA polymerase II promoter);GO:0032039(integrator complex);GO:0016180(snRNA processing)","NA","NA","NA","integrator complex subunit 8 [Source:HGNC Symbol;Acc:HGNC:26048]",{"v":0.014055,"d":"0.01"},{"v":0.039264,"d":"0.04"},{"v":0.357961491442543,"d":"0.36"},{"v":-1.4821237003952,"d":"-1.48"},1,1,"down","no"]
[94260,0,"chr19","+",1286154,1300237,"ENST00000215368",4,949,"ENSG00000099617","EFNA2","GO:0016020(membrane);GO:0005886(plasma membrane);GO:0031225(anchored component of membrane);GO:0046875(ephrin receptor binding);GO:0048013(ephrin receptor signaling pathway);GO:0007411(axon guidance);GO:0007267(cell-cell signaling);GO:0030316(osteoclast differentiation);GO:0021772(olfactory bulb development);GO:0046849(bone remodeling);GO:0031594(neuromuscular junction);GO:0043204(perikaryon)","04014(Ras signaling pathway);04015(Rap1 signaling pathway);04010(MAPK signaling pathway);04151(PI3K-Akt signaling pathway);04360(Axon guidance)","K05462","NA","ephrin A2 [Source:HGNC Symbol;Acc:HGNC:3222]",0,0,1,0,1,1,"no","no"]
[100444,0,"chr19","+",36115484,36121885,"ENST00000392178",4,791,"MSTRG.8087","TBCB","GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0007275(multicellular organism development);GO:0007399(nervous system development);GO:0030154(cell differentiation);GO:0005874(microtubule);GO:0015630(microtubule cytoskeleton)","NA","NA","NA","tubulin folding cofactor B [Source:HGNC Symbol;Acc:HGNC:1989]",{"v":0.138409,"d":"0.14"},{"v":0.544967,"d":"0.54"},{"v":0.253976846304455,"d":"0.25"},{"v":-1.97723111459981,"d":"-1.98"},1,1,"down","no"]
[126739,0,"chr21","+",33571869,33576764,"ENST00000470533",6,798,"MSTRG.10037","SON","GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0006397(mRNA processing);GO:0008380(RNA splicing);GO:0005634(nucleus);GO:0016607(nuclear speck);GO:0003677(DNA binding);GO:0007049(cell cycle);GO:0043484(regulation of RNA splicing);GO:0051726(regulation of cell cycle);GO:0005515(protein binding);GO:0043066(negative regulation of apoptotic process);GO:0000226(microtubule cytoskeleton organization);GO:0000281(mitotic cytokinesis);GO:0048024(regulation of mRNA splicing, via spliceosome);GO:0050733(RS domain binding)","NA","NA","NA","SON DNA binding protein [Source:HGNC Symbol;Acc:HGNC:11183]",{"v":0.055998,"d":"0.06"},0,"inf","inf",1,1,"up","no"]
[97596,0,"chr19","-",14480306,14480896,"ENST00000587969",2,484,"MSTRG.7903","GIPC1","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005829(cytosol);GO:0005515(protein binding);GO:0007186(G-protein coupled receptor signaling pathway);GO:0031410(cytoplasmic vesicle);GO:0003779(actin binding);GO:0017022(myosin binding);GO:0030165(PDZ domain binding);GO:0042803(protein homodimerization activity);GO:0006605(protein targeting);GO:0007268(chemical synaptic transmission);GO:0014047(glutamate secretion);GO:0030511(positive regulation of transforming growth factor beta receptor signaling pathway);GO:0031647(regulation of protein stability);GO:0032435(negative regulation of proteasomal ubiquitin-dependent protein catabolic process);GO:0043542(endothelial cell migration);GO:0048167(regulation of synaptic plasticity);GO:0005903(brush border);GO:0008021(synaptic vesicle);GO:0012506(vesicle membrane);GO:0030139(endocytic vesicle);GO:0043197(dendritic spine);GO:0043198(dendritic shaft);GO:0045296(cadherin binding);GO:0070062(extracellular exosome);GO:0005938(cell cortex);GO:0005102(receptor binding);GO:0032467(positive regulation of cytokinesis)","NA","NA","NA","GIPC PDZ domain containing family member 1 [Source:HGNC Symbol;Acc:HGNC:1226]",{"v":0.000371,"d":"0.00"},{"v":0.150521,"d":"0.15"},{"v":0.00246477235734549,"d":"0.00"},{"v":-8.66432987704244,"d":"-8.66"},1,1,"down","no"]
[61010,0,"chr15","+",39588848,39589843,"ENST00000490247",3,431,"ENSG00000137801","THBS1","GO:0005615(extracellular space);GO:0006954(inflammatory response);GO:0008201(heparin binding);GO:0050840(extracellular matrix binding);GO:0016525(negative regulation of angiogenesis);GO:0045766(positive regulation of angiogenesis);GO:0008284(positive regulation of cell proliferation);GO:0010595(positive regulation of endothelial cell migration);GO:0001937(negative regulation of endothelial cell proliferation);GO:0040037(negative regulation of fibroblast growth factor receptor signaling pathway);GO:0010596(negative regulation of endothelial cell migration);GO:0030335(positive regulation of cell migration);GO:0001953(negative regulation of cell-matrix adhesion);GO:0043032(positive regulation of macrophage activation);GO:0043537(negative regulation of blood vessel endothelial cell migration);GO:0045727(positive regulation of translation);GO:0010763(positive regulation of fibroblast migration);GO:0043536(positive regulation of blood vessel endothelial cell migration);GO:0005509(calcium ion binding);GO:0007155(cell adhesion);GO:0005576(extracellular region);GO:0005783(endoplasmic reticulum);GO:0005515(protein binding);GO:0006986(response to unfolded protein);GO:0070062(extracellular exosome);GO:0031012(extracellular matrix);GO:0016529(sarcoplasmic reticulum);GO:0009986(cell surface);GO:0043066(negative regulation of apoptotic process);GO:0002576(platelet degranulation);GO:0000187(activation of MAPK activity);GO:0042535(positive regulation of tumor necrosis factor biosynthetic process);GO:0009897(external side of plasma membrane);GO:0005788(endoplasmic reticulum lumen);GO:0031093(platelet alpha granule lumen);GO:0034976(response to endoplasmic reticulum stress);GO:0030198(extracellular matrix organization);GO:0042327(positive regulation of phosphorylation);GO:0043154(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process);GO:0050921(positive regulation of chemotaxis);GO:0001786(phosphatidylserine binding);GO:0042802(identical protein binding);GO:0045652(regulation of megakaryocyte differentiation);GO:0051897(positive regulation of protein kinase B signaling);GO:0002040(sprouting angiogenesis);GO:0030511(positive regulation of transforming growth factor beta receptor signaling pathway);GO:0016477(cell migration);GO:0032695(negative regulation of interleukin-12 production);GO:0051895(negative regulation of focal adhesion assembly);GO:0006955(immune response);GO:0017134(fibroblast growth factor binding);GO:0002544(chronic inflammatory response);GO:0042493(response to drug);GO:0030194(positive regulation of blood coagulation);GO:0051918(negative regulation of fibrinolysis);GO:2000379(positive regulation of reactive oxygen species metabolic process);GO:0007050(cell cycle arrest);GO:0048661(positive regulation of smooth muscle cell proliferation);GO:0030169(low-density lipoprotein particle binding);GO:0032570(response to progesterone);GO:0009749(response to glucose);GO:0051592(response to calcium ion);GO:0005577(fibrinogen complex);GO:0031091(platelet alpha granule);GO:0018149(peptide cross-linking);GO:0005178(integrin binding);GO:2001237(negative regulation of extrinsic apoptotic signaling pathway);GO:0010757(negative regulation of plasminogen activation);GO:0050431(transforming growth factor beta binding);GO:0001666(response to hypoxia);GO:0001968(fibronectin binding);GO:0043394(proteoglycan binding);GO:0043236(laminin binding);GO:0070051(fibrinogen binding);GO:0070052(collagen V binding);GO:0002581(negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II);GO:0002605(negative regulation of dendritic cell antigen processing and presentation);GO:0009612(response to mechanical stimulus);GO:0010748(negative regulation of plasma membrane long-chain fatty acid transport);GO:0010751(negative regulation of nitric oxide mediated signal transduction);GO:0010754(negative regulation of cGMP-mediated signaling);GO:0010759(positive regulation of macrophage chemotaxis);GO:0030823(regulation of cGMP metabolic process);GO:0032026(response to magnesium ion);GO:0032914(positive regulation of transforming growth factor beta1 production);GO:0033574(response to testosterone);GO:0034605(cellular response to heat);GO:0036066(protein O-linked fucosylation);GO:0043652(engulfment of apoptotic cell);GO:0048266(behavioral response to pain);GO:0071356(cellular response to tumor necrosis factor);GO:0071363(cellular response to growth factor stimulus);GO:0071636(positive regulation of transforming growth factor beta production);GO:1902043(positive regulation of extrinsic apoptotic signaling pathway via death domain receptors);GO:2000353(positive regulation of endothelial cell apoptotic process);GO:2001027(negative regulation of endothelial cell chemotaxis);GO:0005737(cytoplasm);GO:0030141(secretory granule)","04015(Rap1 signaling pathway);04350(TGF-beta signaling pathway);04151(PI3K-Akt signaling pathway);04512(ECM-receptor interaction);04145(Phagosome);04115(p53 signaling pathway);04510(Focal adhesion);05206(MicroRNAs in cancer);05205(Proteoglycans in cancer);05219(Bladder cancer);05165(Human papillomavirus infection);05144(Malaria)","NA","NA","thrombospondin 1 [Source:HGNC Symbol;Acc:HGNC:11785]",0,0,1,0,1,1,"no","no"]
[1266,0,"chr1","-",8656193,8703219,"ENST00000468247",2,414,"MSTRG.122","RERE","GO:0005634(nucleus);GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0043565(sequence-specific DNA binding);GO:0005515(protein binding);GO:0007275(multicellular organism development);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0001105(RNA polymerase II transcription coactivator activity);GO:0001106(RNA polymerase II transcription corepressor activity);GO:0003682(chromatin binding);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0006338(chromatin remodeling);GO:0021549(cerebellum development);GO:0021691(cerebellar Purkinje cell layer maturation);GO:0021930(cerebellar granule cell precursor proliferation);GO:0021942(radial glia guided migration of Purkinje cell);GO:0048755(branching morphogenesis of a nerve);GO:0048813(dendrite morphogenesis);GO:0000118(histone deacetylase complex);GO:0006607(NLS-bearing protein import into nucleus);GO:0008267(poly-glutamine tract binding)","NA","NA","NA","arginine-glutamic acid dipeptide repeats [Source:HGNC Symbol;Acc:HGNC:9965]",{"v":0.208892,"d":"0.21"},0,"inf","inf",1,1,"up","no"]
[143514,0,"chr3","+",184328669,184331853,"ENST00000464548",4,637,"MSTRG.11394","EIF4G1","GO:0003723(RNA binding);GO:0016020(membrane);GO:0003743(translation initiation factor activity);GO:0006412(translation);GO:0006413(translational initiation);GO:0006446(regulation of translational initiation);GO:0005515(protein binding);GO:0008190(eukaryotic initiation factor 4E binding);GO:0005829(cytosol);GO:0045296(cadherin binding);GO:0043488(regulation of mRNA stability);GO:0000289(nuclear-transcribed mRNA poly(A) tail shortening);GO:0006417(regulation of translation);GO:0016032(viral process);GO:0010507(negative regulation of autophagy);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0008135(translation factor activity, RNA binding);GO:0007005(mitochondrion organization);GO:0005524(ATP binding);GO:0000184(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay);GO:0016281(eukaryotic translation initiation factor 4F complex);GO:1901215(negative regulation of neuron death);GO:0033138(positive regulation of peptidyl-serine phosphorylation);GO:0008284(positive regulation of cell proliferation);GO:1905606(regulation of presynapse assembly);GO:0010801(negative regulation of peptidyl-threonine phosphorylation);GO:0030307(positive regulation of cell growth);GO:0034645(cellular macromolecule biosynthetic process);GO:0022627(cytosolic small ribosomal subunit);GO:0003729(mRNA binding);GO:0031369(translation initiation factor binding);GO:0032947(protein complex scaffold);GO:0002191(cap-dependent translational initiation);GO:0032270(positive regulation of cellular protein metabolic process);GO:0032502(developmental process);GO:0060964(regulation of gene silencing by miRNA);GO:0080135(regulation of cellular response to stress);GO:1900087(positive regulation of G1/S transition of mitotic cell cycle);GO:1905537(positive regulation of eukaryotic translation initiation factor 4F complex assembly);GO:1905612(positive regulation of mRNA cap binding);GO:1905618(positive regulation of miRNA mediated inhibition of translation);GO:1905696(regulation of polysome binding);GO:2000507(positive regulation of energy homeostasis);GO:0005844(polysome);GO:0001662(behavioral fear response);GO:0045666(positive regulation of neuron differentiation)","03013(RNA transport);05416(Viral myocarditis)","NA","NA","eukaryotic translation initiation factor 4 gamma 1 [Source:HGNC Symbol;Acc:HGNC:3296]",{"v":0.16987,"d":"0.17"},{"v":0.296721,"d":"0.30"},{"v":0.572490656205661,"d":"0.57"},{"v":-0.804675948150729,"d":"-0.80"},1,1,"down","no"]
[175098,0,"chr7","+",74774011,74783540,"ENST00000449343",6,1074,"MSTRG.13717","NCF1","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005829(cytosol);GO:0055114(oxidation-reduction process);GO:0005515(protein binding);GO:0035091(phosphatidylinositol binding);GO:0008289(lipid binding);GO:0016175(superoxide-generating NADPH oxidase activity);GO:0016176(superoxide-generating NADPH oxidase activator activity);GO:0071800(podosome assembly);GO:0002102(podosome);GO:0002479(antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent);GO:0019898(extrinsic component of membrane);GO:0043325(phosphatidylinositol-3,4-bisphosphate binding);GO:0006612(protein targeting to membrane);GO:0045087(innate immune response);GO:0048010(vascular endothelial growth factor receptor signaling pathway);GO:0005886(plasma membrane);GO:0009055(electron carrier activity);GO:0034599(cellular response to oxidative stress);GO:0034614(cellular response to reactive oxygen species);GO:0045893(positive regulation of transcription, DNA-templated);GO:0071276(cellular response to cadmium ion);GO:0017124(SH3 domain binding);GO:0006968(cellular defense response);GO:0006801(superoxide metabolic process);GO:0042554(superoxide anion generation);GO:0045454(cell redox homeostasis);GO:0045730(respiratory burst);GO:0043020(NADPH oxidase complex);GO:0006915(apoptotic process);GO:0014068(positive regulation of phosphatidylinositol 3-kinase signaling);GO:0045741(positive regulation of epidermal growth factor-activated receptor activity);GO:0046330(positive regulation of JNK cascade);GO:1900745(positive regulation of p38MAPK cascade);GO:0005791(rough endoplasmic reticulum);GO:0005794(Golgi apparatus);GO:0030425(dendrite);GO:0032010(phagolysosome);GO:0043025(neuronal cell body)","04145(Phagosome);04666(Fc gamma R-mediated phagocytosis);04670(Leukocyte transendothelial migration);04062(Chemokine signaling pathway);04380(Osteoclast differentiation);05418(Fluid shear stress and atherosclerosis);05140(Leishmaniasis)","NA","NA","neutrophil cytosolic factor 1 [Source:HGNC Symbol;Acc:HGNC:7660]",{"v":0.391306,"d":"0.39"},0,"inf","inf",1,1,"up","no"]
[178619,0,"chr7","+",129055223,129057239,"ENST00000635637",1,2017,"MSTRG.13962","TPI1P2","NA","NA","NA","NA","triosephosphate isomerase 1 pseudogene 2 [Source:HGNC Symbol;Acc:HGNC:38069]",{"v":0.063878,"d":"0.06"},{"v":0.012574,"d":"0.01"},{"v":5.0801654207094,"d":"5.08"},{"v":2.34487547490129,"d":"2.34"},1,1,"up","no"]
[194825,0,"chr9","+",136662927,136672677,"ENST00000308874",11,1747,"ENSG00000172889","EGFL7","GO:0005509(calcium ion binding);GO:0007155(cell adhesion);GO:0005576(extracellular region);GO:0007275(multicellular organism development);GO:0005615(extracellular space);GO:0030154(cell differentiation);GO:0031012(extracellular matrix);GO:0001525(angiogenesis);GO:0001568(blood vessel development);GO:0001570(vasculogenesis);GO:0001938(positive regulation of endothelial cell proliferation);GO:0045746(negative regulation of Notch signaling pathway)","NA","NA","NA","EGF like domain multiple 7 [Source:HGNC Symbol;Acc:HGNC:20594]",{"v":0.248791,"d":"0.25"},{"v":1.03E-4,"d":"0.00"},{"v":2415.44660194175,"d":"2415.45"},{"v":11.2380742442566,"d":"11.24"},1,1,"up","no"]
[46807,0,"chr12","-",111991814,112005985,"ENST00000550233",4,571,"MSTRG.3728","TMEM116","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0003674(molecular_function);GO:0008150(biological_process);GO:0005575(cellular_component)","NA","NA","NA","transmembrane protein 116 [Source:HGNC Symbol;Acc:HGNC:25084]",0,0,1,0,1,1,"no","no"]
[97543,0,"chr19","+",14397480,14401503,"ENST00000586849",4,568,"MSTRG.7900","ADGRE5","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0004930(G-protein coupled receptor activity);GO:0007186(G-protein coupled receptor signaling pathway);GO:0005509(calcium ion binding);GO:0007155(cell adhesion);GO:0005886(plasma membrane);GO:0004871(signal transducer activity);GO:0007165(signal transduction);GO:0005576(extracellular region);GO:0004888(transmembrane signaling receptor activity);GO:0007166(cell surface receptor signaling pathway);GO:0005615(extracellular space);GO:0005925(focal adhesion);GO:0005515(protein binding);GO:0070062(extracellular exosome);GO:0005887(integral component of plasma membrane);GO:0043312(neutrophil degranulation);GO:0006954(inflammatory response);GO:0006955(immune response);GO:0007267(cell-cell signaling);GO:0030667(secretory granule membrane);GO:0006928(movement of cell or subcellular component)","NA","NA","NA","adhesion G protein-coupled receptor E5 [Source:HGNC Symbol;Acc:HGNC:1711]",{"v":0.606999,"d":"0.61"},{"v":0.238935,"d":"0.24"},{"v":2.54043568334484,"d":"2.54"},{"v":1.34507593963493,"d":"1.35"},1,1,"up","no"]
[53823,0,"chr14","-",24440101,24440926,"ENST00000555561",2,452,"MSTRG.4293","SDR39U1","GO:0005634(nucleus);GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process)","NA","NA","NA","short chain dehydrogenase/reductase family 39U member 1 [Source:HGNC Symbol;Acc:HGNC:20275]",0,{"v":0.059974,"d":"0.06"},"-inf","-inf",1,1,"down","no"]
[116660,0,"chr2","+",176129740,176132029,"ENST00000313173",2,1917,"ENSG00000175879","HOXD8","GO:0005634(nucleus);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0043565(sequence-specific DNA binding);GO:0007275(multicellular organism development);GO:0006366(transcription from RNA polymerase II promoter);GO:0006351(transcription, DNA-templated);GO:0001228(transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0000977(RNA polymerase II regulatory region sequence-specific DNA binding);GO:0008595(anterior/posterior axis specification, embryo);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0009952(anterior/posterior pattern specification);GO:0048705(skeletal system morphogenesis)","NA","NA","NA","homeobox D8 [Source:HGNC Symbol;Acc:HGNC:5139]",0,0,1,0,1,1,"no","no"]
[188161,0,"chr8","-",143915153,143953920,"ENST00000354958",32,14751,"MSTRG.14615","PLEC","GO:0003723(RNA binding);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0003779(actin binding);GO:0005925(focal adhesion);GO:0045111(intermediate filament cytoskeleton);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0008092(cytoskeletal protein binding);GO:0030054(cell junction);GO:0045296(cadherin binding);GO:0070062(extracellular exosome);GO:0042383(sarcolemma);GO:0031012(extracellular matrix);GO:0005886(plasma membrane);GO:0008307(structural constituent of muscle);GO:0030506(ankyrin binding);GO:0031581(hemidesmosome assembly);GO:0030056(hemidesmosome);GO:0043034(costamere);GO:0016528(sarcoplasm);GO:0005903(brush border);GO:0043292(contractile fiber)","NA","NA","NA","plectin [Source:HGNC Symbol;Acc:HGNC:9069]",{"v":1.207489,"d":"1.21"},0,"inf","inf",1,1,"up","no"]
[117275,0,"chr2","-",189746660,189763227,"ENST00000519810",9,2216,"ENSG00000128694","OSGEPL1","GO:0046872(metal ion binding);GO:0016740(transferase activity);GO:0008033(tRNA processing);GO:0005739(mitochondrion);GO:0016746(transferase activity, transferring acyl groups);GO:0006508(proteolysis);GO:0004222(metalloendopeptidase activity);GO:0002949(tRNA threonylcarbamoyladenosine modification);GO:0061711(N(6)-L-threonylcarbamoyladenine synthase);GO:0000408(EKC/KEOPS complex)","NA","NA","NA","O-sialoglycoprotein endopeptidase like 1 [Source:HGNC Symbol;Acc:HGNC:23075]",{"v":0.176074,"d":"0.18"},{"v":0.117165,"d":"0.12"},{"v":1.50278666837366,"d":"1.50"},{"v":0.587640222611806,"d":"0.59"},1,1,"up","no"]
[184687,0,"chr8","+",73008908,73012505,"ENST00000518695",1,3598,"MSTRG.14393","TERF1","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0003677(DNA binding);GO:0001650(fibrillar center);GO:0051301(cell division);GO:0005694(chromosome);GO:0042803(protein homodimerization activity);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0042162(telomeric DNA binding);GO:0007049(cell cycle);GO:0016604(nuclear body);GO:0005819(spindle);GO:0000781(chromosome, telomeric region);GO:0005654(nucleoplasm);GO:0000784(nuclear chromosome, telomeric region);GO:0003720(telomerase activity);GO:0007004(telomere maintenance via telomerase);GO:0000783(nuclear telomere cap complex);GO:0005730(nucleolus);GO:0090656(t-circle formation);GO:0043130(ubiquitin binding);GO:1904357(negative regulation of telomere maintenance via telomere lengthening);GO:0008156(negative regulation of DNA replication);GO:0051974(negative regulation of telomerase activity);GO:0032211(negative regulation of telomere maintenance via telomerase);GO:0098505(G-rich strand telomeric DNA binding);GO:0000723(telomere maintenance);GO:0003691(double-stranded telomeric DNA binding);GO:0061820(telomeric D-loop disassembly);GO:0008301(DNA binding, bending);GO:0071532(ankyrin repeat binding);GO:0016233(telomere capping);GO:0031627(telomeric loop formation);GO:0032214(negative regulation of telomere maintenance via semi-conservative replication);GO:0042493(response to drug);GO:0045141(meiotic telomere clustering);GO:1904792(positive regulation of shelterin complex assembly);GO:1904850(negative regulation of establishment of protein localization to telomere);GO:1904911(negative regulation of establishment of RNA localization to telomere);GO:1904914(negative regulation of establishment of macromolecular complex localization to telomere);GO:1905778(negative regulation of exonuclease activity);GO:1905839(negative regulation of telomeric D-loop disassembly);GO:0070187(shelterin complex)","NA","NA","NA","telomeric repeat binding factor 1 [Source:HGNC Symbol;Acc:HGNC:11728]",0,{"v":0.056578,"d":"0.06"},"-inf","-inf",1,1,"down","no"]
[11287,0,"chr1","+",153968261,153973019,"ENST00000492729",5,835,"MSTRG.1001","CREB3L4","GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0035497(cAMP response element binding);GO:0030968(endoplasmic reticulum unfolded protein response);GO:0005634(nucleus);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005654(nucleoplasm);GO:0006366(transcription from RNA polymerase II promoter);GO:0006351(transcription, DNA-templated);GO:0005739(mitochondrion);GO:0031965(nuclear membrane);GO:0005794(Golgi apparatus);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0000139(Golgi membrane);GO:0006986(response to unfolded protein);GO:0000977(RNA polymerase II regulatory region sequence-specific DNA binding);GO:0001228(transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding);GO:0007283(spermatogenesis)","04668(TNF signaling pathway);04024(cAMP signaling pathway);04022(cGMP - PKG signaling pathway);04151(PI3K-Akt signaling pathway);04152(AMPK signaling pathway);04911(Insulin secretion);04922(Glucagon signaling pathway);04915(Estrogen signaling pathway);04926(Relaxin signaling pathway);04918(Thyroid hormone synthesis);04916(Melanogenesis);04925(Aldosterone synthesis and secretion);04927(Cortisol synthesis and secretion);04261(Adrenergic signaling in cardiomyocytes);04962(Vasopressin-regulated water reabsorption);04725(Cholinergic synapse);04728(Dopaminergic synapse);04211(Longevity regulating pathway - mammal);05203(Viral carcinogenesis);05215(Prostate cancer);05016(Huntington's disease);05030(Cocaine addiction);05031(Amphetamine addiction);05034(Alcoholism);04931(Insulin resistance);05161(Hepatitis B);05165(Human papillomavirus infection)","NA","NA","cAMP responsive element binding protein 3 like 4 [Source:HGNC Symbol;Acc:HGNC:18854]",0,0,1,0,1,1,"no","no"]
[46346,0,"chr12","-",109052350,109053952,"ENST00000478808",2,656,"ENSG00000256262","USP30-AS1","NA","NA","NA","NA","USP30 antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:40909]",{"v":0.201224,"d":"0.20"},{"v":0.091582,"d":"0.09"},{"v":2.19720032320762,"d":"2.20"},{"v":1.13566640918914,"d":"1.14"},1,1,"up","no"]
[171247,0,"chr7","-",1428619,1459365,"ENST00000472100",16,5248,"ENSG00000164877","MICALL2","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0046872(metal ion binding);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0005856(cytoskeleton);GO:0042995(cell projection);GO:0005515(protein binding);GO:0030054(cell junction);GO:0005923(bicellular tight junction);GO:0005768(endosome);GO:0051015(actin filament binding);GO:0001725(stress fiber);GO:0055037(recycling endosome);GO:0030041(actin filament polymerization);GO:0043005(neuron projection);GO:0005911(cell-cell junction);GO:0031175(neuron projection development);GO:1903955(positive regulation of protein targeting to mitochondrion);GO:0031532(actin cytoskeleton reorganization);GO:0070830(bicellular tight junction assembly);GO:0032456(endocytic recycling);GO:0031005(filamin binding);GO:0034446(substrate adhesion-dependent cell spreading);GO:0032432(actin filament bundle);GO:0017137(Rab GTPase binding);GO:0042805(actinin binding)","04530(Tight junction)","NA","NA","MICAL like 2 [Source:HGNC Symbol;Acc:HGNC:29672]",{"v":0.025232,"d":"0.03"},{"v":0.137884,"d":"0.14"},{"v":0.182994401090772,"d":"0.18"},{"v":-2.45012858649906,"d":"-2.45"},1,1,"down","no"]
[62415,0,"chr15","-",49859639,50119226,"ENST00000558906",28,4179,"ENSG00000104043","ATP8B4","GO:0016021(integral component of membrane);GO:0005524(ATP binding);GO:0000287(magnesium ion binding);GO:0004012(phospholipid-translocating ATPase activity);GO:0015914(phospholipid transport);GO:0045332(phospholipid translocation);GO:0006810(transport);GO:0016020(membrane);GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0016787(hydrolase activity);GO:0005794(Golgi apparatus);GO:0005886(plasma membrane);GO:0006869(lipid transport);GO:0043312(neutrophil degranulation);GO:0035579(specific granule membrane);GO:0070821(tertiary granule membrane);GO:0007030(Golgi organization)","NA","NA","NA","ATPase phospholipid transporting 8B4 (putative) [Source:HGNC Symbol;Acc:HGNC:13536]",0,0,1,0,1,1,"no","no"]
[79924,0,"chr17","-",16616848,16617881,"ENST00000414124",1,1034,"ENSG00000235554","AC005822.1","NA","NA","NA","NA","NA",{"v":0.231264,"d":"0.23"},{"v":0.073828,"d":"0.07"},{"v":3.13247006555778,"d":"3.13"},{"v":1.64730072296208,"d":"1.65"},1,1,"up","no"]
[12619,0,"chr1","+",160317403,160317706,"ENST00000439961",1,304,"MSTRG.1118","SUMO1P3","NA","NA","NA","NA","SUMO1 pseudogene 3 [Source:HGNC Symbol;Acc:HGNC:33150]",0,0,1,0,1,1,"no","no"]
[176449,0,"chr7","+",98900680,99013243,"ENST00000456197",63,11654,"ENSG00000196367","TRRAP","GO:0005634(nucleus);GO:0005794(Golgi apparatus);GO:0005654(nucleoplasm);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0016569(covalent chromatin modification);GO:0016301(kinase activity);GO:0005515(protein binding);GO:0000123(histone acetyltransferase complex);GO:0016310(phosphorylation);GO:0016578(histone deubiquitination);GO:0016573(histone acetylation);GO:0016579(protein deubiquitination);GO:0043967(histone H4 acetylation);GO:1904837(beta-catenin-TCF complex assembly);GO:0033276(transcription factor TFTC complex);GO:0003712(transcription cofactor activity);GO:0036459(thiol-dependent ubiquitinyl hydrolase activity);GO:0006281(DNA repair);GO:0000125(PCAF complex);GO:0030914(STAGA complex);GO:0043968(histone H2A acetylation);GO:0035267(NuA4 histone acetyltransferase complex);GO:0000812(Swr1 complex);GO:0016740(transferase activity)","05166(HTLV-I infection)","NA","NA","transformation/transcription domain associated protein [Source:HGNC Symbol;Acc:HGNC:12347]",0,0,1,0,1,1,"no","no"]
[174958,0,"chr7","-",73736663,73738510,"ENST00000486114",4,568,"ENSG00000106077","ABHD11","GO:0016787(hydrolase activity);GO:0003674(molecular_function);GO:0008150(biological_process);GO:0005575(cellular_component);GO:0005739(mitochondrion)","NA","NA","NA","abhydrolase domain containing 11 [Source:HGNC Symbol;Acc:HGNC:16407]",0,0,1,0,1,1,"no","no"]
[173536,0,"chr7","-",43961590,43973323,"ENST00000418645",7,1148,"MSTRG.13619","AC004951.3","NA","NA","NA","NA","NA",{"v":0.006197,"d":"0.01"},{"v":0.035161,"d":"0.04"},{"v":0.176246409374022,"d":"0.18"},{"v":-2.50433422875782,"d":"-2.50"},1,1,"down","no"]
[113619,0,"chr2","+",112590796,112591939,"ENST00000436885",2,529,"MSTRG.9058","AC012442.1","NA","NA","NA","NA","NA",{"v":0.077977,"d":"0.08"},{"v":0.013698,"d":"0.01"},{"v":5.69258285881151,"d":"5.69"},{"v":2.50908338576927,"d":"2.51"},1,1,"up","no"]
[2957,0,"chr1","+",25820232,25829658,"ENST00000464008",7,1201,"MSTRG.273","MTFR1L","GO:0005515(protein binding);GO:0009060(aerobic respiration);GO:0005739(mitochondrion);GO:0000266(mitochondrial fission)","NA","NA","NA","mitochondrial fission regulator 1 like [Source:HGNC Symbol;Acc:HGNC:28836]",{"v":0.198236,"d":"0.20"},0,"inf","inf",1,1,"up","no"]
[14163,0,"chr1","-",182598623,182604408,"ENST00000367558",5,2427,"ENSG00000143333","RGS16","GO:0016020(membrane);GO:0007186(G-protein coupled receptor signaling pathway);GO:0005096(GTPase activator activity);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0043547(positive regulation of GTPase activity);GO:0007601(visual perception);GO:0009968(negative regulation of signal transduction);GO:0005737(cytoplasm);GO:0008277(regulation of G-protein coupled receptor protein signaling pathway);GO:0005516(calmodulin binding);GO:0031224(intrinsic component of membrane)","NA","NA","NA","regulator of G protein signaling 16 [Source:HGNC Symbol;Acc:HGNC:9997]",{"v":0.327436,"d":"0.33"},{"v":0.228299,"d":"0.23"},{"v":1.43424193710879,"d":"1.43"},{"v":0.520288407600578,"d":"0.52"},1,1,"up","no"]
[77782,0,"chr17","-",2962248,2965895,"ENST00000574885",3,2546,"MSTRG.6302","AC015921.1","NA","NA","NA","NA","NA",0,{"v":0.019989,"d":"0.02"},"-inf","-inf",1,1,"down","no"]
[35132,0,"chr11","+",112088867,112119442,"ENST00000534010",3,460,"MSTRG.2846","SDHD","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0046872(metal ion binding);GO:0055114(oxidation-reduction process);GO:0006099(tricarboxylic acid cycle);GO:0005743(mitochondrial inner membrane);GO:0005739(mitochondrion);GO:0020037(heme binding);GO:0005740(mitochondrial envelope);GO:0006121(mitochondrial electron transport, succinate to ubiquinone);GO:0008177(succinate dehydrogenase (ubiquinone) activity);GO:0048039(ubiquinone binding);GO:0005749(mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone));GO:0000104(succinate dehydrogenase activity);GO:0009055(electron carrier activity)","00020(Citrate cycle (TCA cycle));00190(Oxidative phosphorylation);05010(Alzheimer's disease);05012(Parkinson's disease);05016(Huntington's disease);04932(Non-alcoholic fatty liver disease (NAFLD))","NA","NA","succinate dehydrogenase complex subunit D [Source:HGNC Symbol;Acc:HGNC:10683]",{"v":0.042504,"d":"0.04"},{"v":0.000733,"d":"0.00"},{"v":57.9863574351978,"d":"57.99"},{"v":5.85764160933926,"d":"5.86"},1,1,"up","no"]
[91324,0,"chr18","+",24114273,24123937,"ENST00000579214",4,389,"ENSG00000168234","TTC39C","NA","NA","NA","NA","tetratricopeptide repeat domain 39C [Source:HGNC Symbol;Acc:HGNC:26595]",0,{"v":0.000657,"d":"0.00"},"-inf","-inf",1,1,"down","no"]
[201666,0,"chrY","-",9374969,9377092,"ENST00000432892",8,766,"ENSG00000228383","FAM197Y7","NA","NA","NA","NA","family with sequence similarity 197 Y-linked member 7 [Source:HGNC Symbol;Acc:HGNC:37469]",0,0,1,0,1,1,"no","no"]
[35514,0,"chr11","+",117199382,117204541,"ENST00000525531",6,1048,"MSTRG.2884","TAGLN","GO:0005737(cytoplasm);GO:0051015(actin filament binding);GO:0003779(actin binding);GO:0005515(protein binding);GO:0030855(epithelial cell differentiation);GO:0007517(muscle organ development)","NA","NA","NA","transgelin [Source:HGNC Symbol;Acc:HGNC:11553]",0,0,1,0,1,1,"no","no"]
[3935,0,"chr1","+",32669093,32679908,"ENST00000463378",8,882,"MSTRG.383","RBBP4","GO:0005634(nucleus);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0016569(covalent chromatin modification);GO:0016575(histone deacetylation);GO:0000790(nuclear chromatin);GO:0005515(protein binding);GO:0007049(cell cycle);GO:0006260(DNA replication);GO:0043234(protein complex);GO:0035098(ESC/E(Z) complex);GO:0034080(CENP-A containing nucleosome assembly);GO:1901796(regulation of signal transduction by p53 class mediator);GO:0004407(histone deacetylase activity);GO:0008285(negative regulation of cell proliferation);GO:0006335(DNA replication-dependent nucleosome assembly);GO:0006336(DNA replication-independent nucleosome assembly);GO:0042826(histone deacetylase binding);GO:0045814(negative regulation of gene expression, epigenetic);GO:0016589(NURF complex);GO:0031492(nucleosomal DNA binding);GO:0016580(Sin3 complex);GO:0043044(ATP-dependent chromatin remodeling);GO:0016581(NuRD complex);GO:0051726(regulation of cell cycle);GO:0042393(histone binding);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:0000980(RNA polymerase II distal enhancer sequence-specific DNA binding);GO:0031497(chromatin assembly);GO:0008094(DNA-dependent ATPase activity);GO:0006338(chromatin remodeling);GO:0033186(CAF-1 complex);GO:0060416(response to growth hormone)","04218(Cellular senescence)","NA","NA","RB binding protein 4, chromatin remodeling factor [Source:HGNC Symbol;Acc:HGNC:9887]",{"v":0.149161,"d":"0.15"},{"v":0.440925,"d":"0.44"},{"v":0.338291092589443,"d":"0.34"},{"v":-1.56366290429469,"d":"-1.56"},1,1,"down","no"]
[75272,0,"chr16","+",70713987,70716890,"ENST00000625095",1,2904,"ENSG00000279412","AC020763.3","NA","NA","NA","NA","NA",0,0,1,0,1,1,"no","no"]
[70339,0,"chr16","+",19706351,19715383,"ENST00000565916",2,1379,"ENSG00000261312","AC002550.1","NA","NA","NA","NA","NA",{"v":0.000797,"d":"0.00"},{"v":0.077816,"d":"0.08"},{"v":0.0102421095918577,"d":"0.01"},{"v":-6.60934328847474,"d":"-6.61"},1,1,"down","no"]
[58893,0,"chr14","-",102251961,102305135,"ENST00000524207",6,574,"MSTRG.4699","MOK","GO:0004672(protein kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0004674(protein serine/threonine kinase activity);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0042995(cell projection);GO:0051726(regulation of cell cycle);GO:0035556(intracellular signal transduction);GO:0005929(cilium);GO:0097546(ciliary base);GO:0010468(regulation of gene expression);GO:0007165(signal transduction);GO:0004693(cyclin-dependent protein serine/threonine kinase activity)","NA","NA","NA","MOK protein kinase [Source:HGNC Symbol;Acc:HGNC:9833]",{"v":0.000954,"d":"0.00"},0,"inf","inf",1,1,"up","no"]
[139649,0,"chr3","-",121833936,121834992,"ENST00000471726",2,571,"ENSG00000173226","IQCB1","GO:0005737(cytoplasm);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0060271(cilium assembly);GO:0005516(calmodulin binding);GO:0005813(centrosome);GO:0005815(microtubule organizing center);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0030030(cell projection organization);GO:0005814(centriole);GO:0097711(ciliary basal body docking);GO:0019899(enzyme binding);GO:0045494(photoreceptor cell maintenance);GO:0048496(maintenance of animal organ identity);GO:0001750(photoreceptor outer segment);GO:0032391(photoreceptor connecting cilium)","NA","NA","NA","IQ motif containing B1 [Source:HGNC Symbol;Acc:HGNC:28949]",{"v":0.947516,"d":"0.95"},{"v":0.571421,"d":"0.57"},{"v":1.65817497081836,"d":"1.66"},{"v":0.729596248216829,"d":"0.73"},1,1,"up","no"]
[173907,0,"chr7","-",47695730,47979581,"ENST00000436444",9,2121,"MSTRG.13637","HUS1","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0000077(DNA damage checkpoint);GO:0005515(protein binding);GO:0006974(cellular response to DNA damage stimulus);GO:0005730(nucleolus);GO:0030896(checkpoint clamp complex);GO:0005654(nucleoplasm);GO:0031573(intra-S DNA damage checkpoint);GO:1901796(regulation of signal transduction by p53 class mediator);GO:0006260(DNA replication);GO:0006281(DNA repair);GO:0071479(cellular response to ionizing radiation);GO:0000724(double-strand break repair via homologous recombination);GO:0006289(nucleotide-excision repair);GO:0033314(mitotic DNA replication checkpoint);GO:0044778(meiotic DNA integrity checkpoint);GO:0035861(site of double-strand break);GO:0001932(regulation of protein phosphorylation);GO:0006468(protein phosphorylation);GO:0007093(mitotic cell cycle checkpoint);GO:0008156(negative regulation of DNA replication);GO:0009411(response to UV);GO:0009790(embryo development)","04218(Cellular senescence)","NA","NA","HUS1 checkpoint clamp component [Source:HGNC Symbol;Acc:HGNC:5309]",{"v":1.328606,"d":"1.33"},{"v":0.251453,"d":"0.25"},{"v":5.28371504814021,"d":"5.28"},{"v":2.4015526638368,"d":"2.40"},1,1,"up","no"]
[105650,"o","chr19","+",54909054,54916286,"MSTRG.8434.9",2,751,"MSTRG.8434","NCR1","NA","NA","NA","NA","NA",{"v":1.580698,"d":"1.58"},{"v":0.612845,"d":"0.61"},{"v":2.57927861041536,"d":"2.58"},{"v":1.36696761963924,"d":"1.37"},1,1,"up","no"]
[121658,0,"chr20","+",3208898,3218596,"ENST00000460676",6,488,"ENSG00000125877","ITPA","GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0005829(cytosol);GO:0016787(hydrolase activity);GO:0009117(nucleotide metabolic process);GO:0042802(identical protein binding);GO:0004551(nucleotide diphosphatase activity);GO:0035529(NADH pyrophosphatase activity);GO:0035870(dITP diphosphatase activity);GO:0047429(nucleoside-triphosphate diphosphatase activity);GO:0006193(ITP catabolic process);GO:0009143(nucleoside triphosphate catabolic process);GO:0051276(chromosome organization);GO:0006195(purine nucleotide catabolic process);GO:0036220(ITP diphosphatase activity);GO:0036222(XTP diphosphatase activity)","00230(Purine metabolism);00983(Drug metabolism - other enzymes)","NA","NA","inosine triphosphatase [Source:HGNC Symbol;Acc:HGNC:6176]",{"v":0.295918,"d":"0.30"},{"v":0.032464,"d":"0.03"},{"v":9.11526614095614,"d":"9.12"},{"v":3.18828477964699,"d":"3.19"},1,1,"up","no"]
[161299,0,"chr5","+",176061122,176090439,"ENST00000511680",6,557,"ENSG00000182230","FAM153B","NA","NA","NA","NA","family with sequence similarity 153 member B [Source:HGNC Symbol;Acc:HGNC:27323]",{"v":0.356938,"d":"0.36"},{"v":0.093062,"d":"0.09"},{"v":3.83548602007264,"d":"3.84"},{"v":1.93940940284455,"d":"1.94"},1,1,"up","no"]
[116531,0,"chr2","+",174410082,174427895,"ENST00000549848",4,943,"MSTRG.9247","SCRN3","GO:0006508(proteolysis);GO:0016805(dipeptidase activity);GO:0006887(exocytosis)","NA","NA","NA","secernin 3 [Source:HGNC Symbol;Acc:HGNC:30382]",{"v":0.168992,"d":"0.17"},0,"inf","inf",1,1,"up","no"]
[35534,0,"chr11","-",117229506,117231868,"ENST00000524507",3,553,"MSTRG.2885","PCSK7","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016787(hydrolase activity);GO:0005794(Golgi apparatus);GO:0008233(peptidase activity);GO:0006508(proteolysis);GO:0004252(serine-type endopeptidase activity);GO:0008236(serine-type peptidase activity);GO:0030173(integral component of Golgi membrane);GO:0016486(peptide hormone processing);GO:0016485(protein processing)","NA","NA","NA","proprotein convertase subtilisin/kexin type 7 [Source:HGNC Symbol;Acc:HGNC:8748]",{"v":0.197062,"d":"0.20"},{"v":0.119473,"d":"0.12"},{"v":1.64942706720347,"d":"1.65"},{"v":0.721964987596634,"d":"0.72"},1,1,"up","no"]
[169217,0,"chr6","-",131825981,131828413,"ENST00000455305",1,2433,"ENSG00000237115","AL139805.2","NA","NA","NA","NA","NA",0,0,1,0,1,1,"no","no"]
[33265,0,"chr11","+",75583196,75594665,"ENST00000527803",2,651,"ENSG00000255326","AP001922.5","NA","NA","NA","NA","NA",0,0,1,0,1,1,"no","no"]
[128592,0,"chr22","-",19875519,19941807,"ENST00000474308",17,1854,"MSTRG.10136","TXNRD2","GO:0005623(cell);GO:0016491(oxidoreductase activity);GO:0050660(flavin adenine dinucleotide binding);GO:0055114(oxidation-reduction process);GO:0045454(cell redox homeostasis);GO:0016668(oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor);GO:0098869(cellular oxidant detoxification);GO:0004791(thioredoxin-disulfide reductase activity);GO:0005829(cytosol);GO:0005739(mitochondrion);GO:0005515(protein binding);GO:0005759(mitochondrial matrix);GO:0034599(cellular response to oxidative stress);GO:0000305(response to oxygen radical)","00450(Selenocompound metabolism);05200(Pathways in cancer);05225(Hepatocellular carcinoma)","NA","NA","thioredoxin reductase 2 [Source:HGNC Symbol;Acc:HGNC:18155]",{"v":0.006472,"d":"0.01"},{"v":0.072673,"d":"0.07"},{"v":0.0890564583820676,"d":"0.09"},{"v":-3.48913595028477,"d":"-3.49"},1,1,"down","no"]
[59648,0,"chr14","-",106463256,106463691,"ENST00000520410",2,361,"MSTRG.4828","IGHV3-42","NA","NA","NA","NA","immunoglobulin heavy variable 3-42 (pseudogene) [Source:HGNC Symbol;Acc:HGNC:5603]",0,0,1,0,1,1,"no","no"]
[80076,0,"chr17","-",17505563,17506323,"ENST00000582268",2,383,"ENSG00000133027","PEMT","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0008168(methyltransferase activity);GO:0016740(transferase activity);GO:0032259(methylation);GO:0006629(lipid metabolic process);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005739(mitochondrion);GO:0008654(phospholipid biosynthetic process);GO:0006644(phospholipid metabolic process);GO:0031966(mitochondrial membrane);GO:0008170(N-methyltransferase activity);GO:0000773(phosphatidyl-N-methylethanolamine N-methyltransferase activity);GO:0004608(phosphatidylethanolamine N-methyltransferase activity);GO:0080101(phosphatidyl-N-dimethylethanolamine N-methyltransferase activity);GO:0006656(phosphatidylcholine biosynthetic process);GO:0008283(cell proliferation);GO:1903955(positive regulation of protein targeting to mitochondrion);GO:0008429(phosphatidylethanolamine binding);GO:0008757(S-adenosylmethionine-dependent methyltransferase activity);GO:0006650(glycerophospholipid metabolic process);GO:0006686(sphingomyelin biosynthetic process);GO:0007584(response to nutrient);GO:0008285(negative regulation of cell proliferation);GO:0033273(response to vitamin);GO:0042493(response to drug);GO:0043200(response to amino acid);GO:0045471(response to ethanol);GO:0046498(S-adenosylhomocysteine metabolic process);GO:0046500(S-adenosylmethionine metabolic process);GO:0050747(positive regulation of lipoprotein metabolic process);GO:0031526(brush border membrane);GO:0042383(sarcolemma)","00564(Glycerophospholipid metabolism)","NA","NA","phosphatidylethanolamine N-methyltransferase [Source:HGNC Symbol;Acc:HGNC:8830]",{"v":0.022228,"d":"0.02"},0,"inf","inf",1,1,"up","no"]
[97069,0,"chr19","+",12669755,12673268,"ENST00000547481",8,770,"MSTRG.7845","WDR83","GO:0006397(mRNA processing);GO:0008380(RNA splicing);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005515(protein binding);GO:0005681(spliceosomal complex);GO:0010008(endosome membrane);GO:0000165(MAPK cascade);GO:0000398(mRNA splicing, via spliceosome);GO:0000375(RNA splicing, via transesterification reactions);GO:0071013(catalytic step 2 spliceosome);GO:0016301(kinase activity);GO:0016310(phosphorylation)","NA","NA","NA","WD repeat domain 83 [Source:HGNC Symbol;Acc:HGNC:32672]",0,0,1,0,1,1,"no","no"]
[55096,0,"chr14","-",53036745,53153098,"ENST00000612692",14,12339,"ENSG00000100523","DDHD1","GO:0005737(cytoplasm);GO:0016787(hydrolase activity);GO:0046872(metal ion binding);GO:0006629(lipid metabolic process);GO:0016042(lipid catabolic process);GO:0005829(cytosol);GO:0006654(phosphatidic acid biosynthetic process);GO:0004620(phospholipase activity);GO:0090141(positive regulation of mitochondrial fission)","NA","NA","NA","DDHD domain containing 1 [Source:HGNC Symbol;Acc:HGNC:19714]",0,0,1,0,1,1,"no","no"]
[88600,0,"chr17","+",77127873,77190952,"ENST00000586429",4,575,"MSTRG.7262","SEC14L1","GO:0005737(cytoplasm);GO:0016021(integral component of membrane);GO:0006810(transport);GO:0005794(Golgi apparatus);GO:0065009(regulation of molecular function);GO:0002376(immune system process);GO:0045087(innate immune response);GO:0005515(protein binding);GO:0009968(negative regulation of signal transduction);GO:0039536(negative regulation of RIG-I signaling pathway);GO:0015871(choline transport);GO:0039552(RIG-I binding);GO:0098772(molecular function regulator)","NA","NA","NA","SEC14 like lipid binding 1 [Source:HGNC Symbol;Acc:HGNC:10698]",0,{"v":0.026505,"d":"0.03"},"-inf","-inf",1,1,"down","no"]
[182709,"i","chr8",".",30108686,30109043,"MSTRG.14285.1",1,358,"MSTRG.14285","LEPROTL1","NA","NA","NA","NA","NA",0,0,1,0,1,1,"no","no"]
[145336,0,"chr4","-",2255009,2262022,"ENST00000515378",4,522,"MSTRG.11495","MXD4","GO:0005634(nucleus);GO:0046983(protein dimerization activity);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0003714(transcription corepressor activity);GO:0008285(negative regulation of cell proliferation);GO:0000122(negative regulation of transcription from RNA polymerase II promoter)","NA","NA","NA","MAX dimerization protein 4 [Source:HGNC Symbol;Acc:HGNC:13906]",{"v":1.413396,"d":"1.41"},{"v":1.188191,"d":"1.19"},{"v":1.18953602577363,"d":"1.19"},{"v":0.250398965262773,"d":"0.25"},1,1,"up","no"]
[16655,0,"chr1","-",227918656,227947898,"ENST00000272164",4,3971,"ENSG00000143816","WNT9A","GO:0008285(negative regulation of cell proliferation);GO:0005102(receptor binding);GO:0005576(extracellular region);GO:0007275(multicellular organism development);GO:0016055(Wnt signaling pathway);GO:0005578(proteinaceous extracellular matrix);GO:0005615(extracellular space);GO:0070062(extracellular exosome);GO:0030182(neuron differentiation);GO:0032331(negative regulation of chondrocyte differentiation);GO:0035115(embryonic forelimb morphogenesis);GO:0043154(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process);GO:0045597(positive regulation of cell differentiation);GO:0045880(positive regulation of smoothened signaling pathway);GO:0048704(embryonic skeletal system morphogenesis);GO:0048856(anatomical structure development);GO:0060070(canonical Wnt signaling pathway);GO:0060548(negative regulation of cell death);GO:0061037(negative regulation of cartilage development);GO:0005109(frizzled binding);GO:0045165(cell fate commitment);GO:0071300(cellular response to retinoic acid);GO:0007267(cell-cell signaling);GO:0007093(mitotic cell cycle checkpoint);GO:0061072(iris morphogenesis);GO:0061303(cornea development in camera-type eye);GO:0072498(embryonic skeletal joint development)","04310(Wnt signaling pathway);04390(Hippo signaling pathway);04150(mTOR signaling pathway);04550(Signaling pathways regulating pluripotency of stem cells);04916(Melanogenesis);05200(Pathways in cancer);05205(Proteoglycans in cancer);05225(Hepatocellular carcinoma);05226(Gastric cancer);05217(Basal cell carcinoma);05224(Breast cancer);05166(HTLV-I infection);05165(Human papillomavirus infection)","K01064","NA","Wnt family member 9A [Source:HGNC Symbol;Acc:HGNC:12778]",{"v":0.026372,"d":"0.03"},{"v":0.025547,"d":"0.03"},{"v":1.03229341997103,"d":"1.03"},{"v":0.0458531019332803,"d":"0.05"},1,1,"up","no"]
[3100,0,"chr1","+",26432340,26469226,"ENST00000526219",8,1072,"ENSG00000117682","DHDDS","GO:0016765(transferase activity, transferring alkyl or aryl (other than methyl) groups);GO:0016740(transferase activity);GO:0006486(protein glycosylation);GO:0016020(membrane);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005515(protein binding);GO:0006489(dolichyl diphosphate biosynthetic process);GO:0002094(polyprenyltransferase activity);GO:0016094(polyprenol biosynthetic process)","00900(Terpenoid backbone biosynthesis)","K11778","EC:2.5.1.87","dehydrodolichyl diphosphate synthase subunit [Source:HGNC Symbol;Acc:HGNC:20603]",0,0,1,0,1,1,"no","no"]
[97790,0,"chr19","-",15401445,15418988,"ENST00000596195",4,553,"MSTRG.7919","AKAP8L","GO:0005634(nucleus);GO:0003723(RNA binding);GO:0006397(mRNA processing);GO:0008380(RNA splicing);GO:0005737(cytoplasm);GO:0016607(nuclear speck);GO:0046872(metal ion binding);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0008150(biological_process);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0000785(chromatin);GO:0016363(nuclear matrix);GO:0016605(PML body);GO:0042826(histone deacetylase binding);GO:0031065(positive regulation of histone deacetylation);GO:0033127(regulation of histone phosphorylation);GO:0044839(cell cycle G2/M phase transition);GO:0005521(lamin binding);GO:0007076(mitotic chromosome condensation);GO:0034237(protein kinase A regulatory subunit binding);GO:0051081(nuclear envelope disassembly);GO:0010793(regulation of mRNA export from nucleus);GO:0017151(DEAD/H-box RNA helicase binding);GO:0016301(kinase activity);GO:0016310(phosphorylation)","05169(Epstein-Barr virus infection)","NA","NA","A-kinase anchoring protein 8 like [Source:HGNC Symbol;Acc:HGNC:29857]",0,{"v":0.065051,"d":"0.07"},"-inf","-inf",1,1,"down","no"]
[61186,0,"chr15","-",40531341,40564992,"ENST00000561011",4,1577,"MSTRG.4906","CCDC32","GO:0005515(protein binding)","NA","NA","NA","coiled-coil domain containing 32 [Source:HGNC Symbol;Acc:HGNC:28295]",{"v":0.589697,"d":"0.59"},{"v":0.081009,"d":"0.08"},{"v":7.27940105420385,"d":"7.28"},{"v":2.86381975101771,"d":"2.86"},1,1,"up","no"]
[162318,"j","chr5","+",181316325,181324688,"MSTRG.12618.2",7,1403,"MSTRG.12618","AC138035.1","NA","NA","NA","NA","NA",{"v":2.064534,"d":"2.06"},{"v":0.117494,"d":"0.12"},{"v":17.5713993906072,"d":"17.57"},{"v":4.1351571874001,"d":"4.14"},1,1,"up","no"]
[193674,0,"chr9","-",127940881,127950722,"ENST00000373084",8,3352,"MSTRG.14989","FAM102A","GO:0005515(protein binding)","NA","NA","NA","family with sequence similarity 102 member A [Source:HGNC Symbol;Acc:HGNC:31419]",{"v":0.148296,"d":"0.15"},{"v":0.109996,"d":"0.11"},{"v":1.34819447979927,"d":"1.35"},{"v":0.431028623229133,"d":"0.43"},1,1,"up","no"]
[82437,0,"chr17","+",36486728,36495748,"ENST00000616269",3,616,"MSTRG.6743","ZNHIT3","GO:0046872(metal ion binding);GO:0006355(regulation of transcription, DNA-templated);GO:0005515(protein binding);GO:0005622(intracellular);GO:0046966(thyroid hormone receptor binding)","NA","NA","NA","zinc finger HIT-type containing 3 [Source:HGNC Symbol;Acc:HGNC:12309]",0,{"v":0.155124,"d":"0.16"},"-inf","-inf",1,1,"down","no"]
[88667,0,"chr17","+",77454027,77488810,"ENST00000586433",5,569,"MSTRG.7267","SEPT9","GO:0005737(cytoplasm);GO:0005525(GTP binding);GO:0000166(nucleotide binding);GO:0051301(cell division);GO:0015629(actin cytoskeleton);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0007049(cell cycle);GO:0048471(perinuclear region of cytoplasm);GO:0005874(microtubule);GO:0045296(cadherin binding);GO:0051291(protein heterooligomerization);GO:0001725(stress fiber);GO:0003924(GTPase activity);GO:0005930(axoneme);GO:0031105(septin complex);GO:0097730(non-motile cilium);GO:1902857(positive regulation of non-motile cilium assembly)","05100(Bacterial invasion of epithelial cells)","NA","NA","septin 9 [Source:HGNC Symbol;Acc:HGNC:7323]",{"v":0.320668,"d":"0.32"},{"v":0.216455,"d":"0.22"},{"v":1.48145341987942,"d":"1.48"},{"v":0.567013265539544,"d":"0.57"},1,1,"up","no"]
[71835,0,"chr16","+",30194447,30204118,"ENST00000569959",10,2424,"MSTRG.5833","SLX1A-SULT1A3","NA","NA","NA","NA","SLX1A-SULT1A3 readthrough (NMD candidate) [Source:HGNC Symbol;Acc:HGNC:44437]",{"v":0.050095,"d":"0.05"},{"v":0.201581,"d":"0.20"},{"v":0.248510524305366,"d":"0.25"},{"v":-2.00862114434064,"d":"-2.01"},1,1,"down","no"]
[98401,0,"chr19","+",17747756,17770463,"ENST00000597474",8,556,"MSTRG.7982","FCHO1","GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0072583(clathrin-dependent endocytosis);GO:0016020(membrane);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0005905(clathrin-coated pit);GO:0006897(endocytosis);GO:0061024(membrane organization);GO:0048268(clathrin coat assembly);GO:0035612(AP-2 adaptor complex binding)","NA","NA","NA","FCH domain only 1 [Source:HGNC Symbol;Acc:HGNC:29002]",0,0,1,0,1,1,"no","no"]
[54002,0,"chr14","-",30683045,30683598,"ENST00000557130",1,554,"MSTRG.4295","UBE2CP1","NA","NA","NA","NA","ubiquitin conjugating enzyme E2 C pseudogene 1 [Source:HGNC Symbol;Acc:HGNC:19670]",{"v":0.095884,"d":"0.10"},0,"inf","inf",1,1,"up","no"]
[124692,0,"chr20","-",52085241,52104923,"ENST00000395989",5,762,"ENSG00000020256","ZFP64","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0005515(protein binding)","NA","NA","NA","ZFP64 zinc finger protein [Source:HGNC Symbol;Acc:HGNC:15940]",0,0,1,0,1,1,"no","no"]
[150955,0,"chr4","-",139060601,139084224,"ENST00000512627",5,611,"ENSG00000109381","ELF2","GO:0005634(nucleus);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0043565(sequence-specific DNA binding);GO:0005515(protein binding);GO:0016604(nuclear body);GO:0045893(positive regulation of transcription, DNA-templated);GO:0000981(RNA polymerase II transcription factor activity, sequence-specific DNA binding);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0030154(cell differentiation);GO:0050855(regulation of B cell receptor signaling pathway)","NA","NA","NA","E74 like ETS transcription factor 2 [Source:HGNC Symbol;Acc:HGNC:3317]",{"v":0.708737,"d":"0.71"},{"v":0.238154,"d":"0.24"},{"v":2.97596093284177,"d":"2.98"},{"v":1.57335558747908,"d":"1.57"},1,1,"up","no"]
[132774,0,"chr3","-",3154550,3172923,"ENST00000482844",4,653,"MSTRG.10618","CRBN","GO:0046872(metal ion binding);GO:0005730(nucleolus);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0016567(protein ubiquitination);GO:0005515(protein binding);GO:0032463(negative regulation of protein homooligomerization);GO:0034766(negative regulation of ion transmembrane transport);GO:0090073(positive regulation of protein homodimerization activity);GO:0043161(proteasome-mediated ubiquitin-dependent protein catabolic process);GO:0031464(Cul4A-RING E3 ubiquitin ligase complex)","NA","NA","NA","cereblon [Source:HGNC Symbol;Acc:HGNC:30185]",{"v":0.879229,"d":"0.88"},{"v":0.780619,"d":"0.78"},{"v":1.12632282842206,"d":"1.13"},{"v":0.171620394213165,"d":"0.17"},1,1,"up","no"]
[52941,0,"chr14","+",22766702,22771771,"ENST00000412791",9,1440,"MSTRG.4177","OXA1L","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005739(mitochondrion);GO:0051205(protein insertion into membrane);GO:0005743(mitochondrial inner membrane);GO:0055114(oxidation-reduction process);GO:0042803(protein homodimerization activity);GO:0031966(mitochondrial membrane);GO:0005515(protein binding);GO:0032981(mitochondrial respiratory chain complex I assembly);GO:0043234(protein complex);GO:0006461(protein complex assembly);GO:0051262(protein tetramerization);GO:0051354(negative regulation of oxidoreductase activity);GO:0032780(negative regulation of ATPase activity);GO:0009060(aerobic respiration);GO:0097177(mitochondrial ribosome binding);GO:0005746(mitochondrial respiratory chain);GO:0033615(mitochondrial proton-transporting ATP synthase complex assembly);GO:0097031(mitochondrial respiratory chain complex I biogenesis);GO:0032592(integral component of mitochondrial membrane)","03060(Protein export)","NA","NA","OXA1L, mitochondrial inner membrane protein [Source:HGNC Symbol;Acc:HGNC:8526]",0,0,1,0,1,1,"no","no"]
[74105,0,"chr16","+",66566393,66579135,"ENST00000533915",5,899,"MSTRG.5996","CMTM1","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005125(cytokine activity);GO:0005615(extracellular space);GO:0006935(chemotaxis)","NA","NA","NA","CKLF like MARVEL transmembrane domain containing 1 [Source:HGNC Symbol;Acc:HGNC:19172]",{"v":0.169217,"d":"0.17"},0,"inf","inf",1,1,"up","no"]
[155690,0,"chr5","-",72222449,72223730,"ENST00000522585",2,127,"MSTRG.12110","MRPS27","GO:0030529(intracellular ribonucleoprotein complex);GO:0005840(ribosome);GO:0005739(mitochondrion);GO:0005515(protein binding);GO:0005743(mitochondrial inner membrane);GO:0070125(mitochondrial translational elongation);GO:0070126(mitochondrial translational termination)","NA","NA","NA","mitochondrial ribosomal protein S27 [Source:HGNC Symbol;Acc:HGNC:14512]",0,0,1,0,1,1,"no","no"]
[198136,0,"chrX","+",71366264,71466005,"ENST00000373790",38,7629,"MSTRG.15350","TAF1","GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0005634(nucleus);GO:0000166(nucleotide binding);GO:0004674(protein serine/threonine kinase activity);GO:0005524(ATP binding);GO:0005654(nucleoplasm);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0016746(transferase activity, transferring acyl groups);GO:0005515(protein binding);GO:0007049(cell cycle);GO:0004402(histone acetyltransferase activity);GO:0016573(histone acetylation);GO:0006352(DNA-templated transcription, initiation);GO:0005669(transcription factor TFIID complex);GO:0000209(protein polyubiquitination);GO:0016032(viral process);GO:0003713(transcription coactivator activity);GO:0006366(transcription from RNA polymerase II promoter);GO:0006368(transcription elongation from RNA polymerase II promoter);GO:0001075(transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly);GO:0006367(transcription initiation from RNA polymerase II promoter);GO:1901796(regulation of signal transduction by p53 class mediator);GO:0000790(nuclear chromatin);GO:0071339(MLL1 complex);GO:0046982(protein heterodimerization activity);GO:0050821(protein stabilization);GO:0046777(protein autophosphorylation);GO:0044212(transcription regulatory region DNA binding);GO:0032436(positive regulation of proteasomal ubiquitin-dependent protein catabolic process);GO:0005730(nucleolus);GO:0018105(peptidyl-serine phosphorylation);GO:0043565(sequence-specific DNA binding);GO:0018107(peptidyl-threonine phosphorylation);GO:0002039(p53 binding);GO:0010629(negative regulation of gene expression);GO:0032092(positive regulation of protein binding);GO:0042787(protein ubiquitination involved in ubiquitin-dependent protein catabolic process);GO:0008134(transcription factor binding);GO:0006974(cellular response to DNA damage stimulus);GO:0060261(positive regulation of transcription initiation from RNA polymerase II promoter);GO:0045943(positive regulation of transcription from RNA polymerase I promoter);GO:0061628(H3K27me3 modified histone binding);GO:0000979(RNA polymerase II core promoter sequence-specific DNA binding);GO:0001129(RNA polymerase II transcription factor activity, TBP-class protein binding, involved in preinitiation complex assembly);GO:0017025(TBP-class protein binding);GO:0061631(ubiquitin conjugating enzyme activity);GO:0070577(lysine-acetylated histone binding);GO:0006468(protein phosphorylation);GO:0008284(positive regulation of cell proliferation);GO:0010767(regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage);GO:0030901(midbrain development);GO:0034644(cellular response to UV);GO:0036369(transcription factor catabolic process);GO:0051123(RNA polymerase II transcriptional preinitiation complex assembly);GO:0060260(regulation of transcription initiation from RNA polymerase II promoter);GO:0071318(cellular response to ATP);GO:1902806(regulation of cell cycle G1/S phase transition);GO:1903026(negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding);GO:1905524(negative regulation of protein autoubiquitination);GO:2000059(negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process);GO:2000825(positive regulation of androgen receptor activity);GO:0005667(transcription factor complex)","03022(Basal transcription factors)","K03125","NA","TATA-box binding protein associated factor 1 [Source:HGNC Symbol;Acc:HGNC:11535]",{"v":2.674875,"d":"2.67"},0,"inf","inf",1,1,"up","no"]
[92076,0,"chr18","+",45736553,45739860,"ENST00000586854",3,577,"ENSG00000141469","SLC14A1","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0043231(intracellular membrane-bounded organelle);GO:0005730(nucleolus);GO:0005886(plasma membrane);GO:0005887(integral component of plasma membrane);GO:0055085(transmembrane transport);GO:0016323(basolateral plasma membrane);GO:0015204(urea transmembrane transporter activity);GO:0071918(urea transmembrane transport);GO:0015265(urea channel activity);GO:0015840(urea transport);GO:0005372(water transmembrane transporter activity);GO:0006833(water transport)","NA","NA","NA","solute carrier family 14 member 1 (Kidd blood group) [Source:HGNC Symbol;Acc:HGNC:10918]",{"v":0.082732,"d":"0.08"},{"v":0.047465,"d":"0.05"},{"v":1.74301063941852,"d":"1.74"},{"v":0.801581375768525,"d":"0.80"},1,1,"up","no"]
[166349,0,"chr6","-",43995723,44074652,"ENST00000422059",5,2232,"ENSG00000237686","AL109615.3","NA","NA","NA","NA","NA",{"v":0.023799,"d":"0.02"},{"v":0.045602,"d":"0.05"},{"v":0.521885005043638,"d":"0.52"},{"v":-0.938196144279694,"d":"-0.94"},1,1,"down","no"]
[111749,0,"chr2","-",85599618,85602665,"ENST00000417791",5,915,"MSTRG.8878","TMEM150A","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0005887(integral component of plasma membrane);GO:0005764(lysosome);GO:0090002(establishment of protein localization to plasma membrane);GO:0046854(phosphatidylinositol phosphorylation);GO:0009056(catabolic process)","NA","NA","NA","transmembrane protein 150A [Source:HGNC Symbol;Acc:HGNC:24677]",0,{"v":0.025634,"d":"0.03"},"-inf","-inf",1,1,"down","no"]
[46363,0,"chr12","-",109090125,109093472,"ENST00000536358",2,1049,"ENSG00000189046","ALKBH2","GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0005654(nucleoplasm);GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0015630(microtubule cytoskeleton);GO:0006281(DNA repair);GO:0006974(cellular response to DNA damage stimulus);GO:0051213(dioxygenase activity);GO:0070989(oxidative demethylation);GO:0008198(ferrous iron binding);GO:0006307(DNA dealkylation involved in DNA repair);GO:0103053(1-ethyladenine demethylase activity);GO:0043734(DNA-N1-methyladenine dioxygenase activity);GO:0051747(cytosine C-5 DNA demethylase activity);GO:0035511(oxidative DNA demethylation);GO:0080111(DNA demethylation);GO:0016706(oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors)","NA","NA","NA","alkB homolog 2, alpha-ketoglutarate dependent dioxygenase [Source:HGNC Symbol;Acc:HGNC:32487]",{"v":0.288696,"d":"0.29"},{"v":0.257205,"d":"0.26"},{"v":1.12243541144223,"d":"1.12"},{"v":0.166632430023955,"d":"0.17"},1,1,"up","no"]
[146140,0,"chr4","+",15681752,15686606,"ENST00000509022",2,521,"MSTRG.11546","FAM200B","GO:0003676(nucleic acid binding);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0005737(cytoplasm);GO:0000981(RNA polymerase II transcription factor activity, sequence-specific DNA binding);GO:0005654(nucleoplasm);GO:0003677(DNA binding)","NA","NA","NA","family with sequence similarity 200 member B [Source:HGNC Symbol;Acc:HGNC:27740]",{"v":0.846554,"d":"0.85"},{"v":1.742211,"d":"1.74"},{"v":0.485907849278876,"d":"0.49"},{"v":-1.04124535717543,"d":"-1.04"},1,1,"down","no"]
[185243,0,"chr8","+",86442272,86452596,"ENST00000524036",4,820,"MSTRG.14433","WWP1","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0016740(transferase activity);GO:0016567(protein ubiquitination);GO:0004842(ubiquitin-protein transferase activity);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0007165(signal transduction);GO:0061630(ubiquitin protein ligase activity);GO:0006511(ubiquitin-dependent protein catabolic process);GO:0043161(proteasome-mediated ubiquitin-dependent protein catabolic process);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0034220(ion transmembrane transport);GO:0042787(protein ubiquitination involved in ubiquitin-dependent protein catabolic process);GO:0016032(viral process);GO:0045892(negative regulation of transcription, DNA-templated);GO:0046718(viral entry into host cell);GO:0000151(ubiquitin ligase complex);GO:0007417(central nervous system development)","04120(Ubiquitin mediated proteolysis);04144(Endocytosis)","NA","NA","WW domain containing E3 ubiquitin protein ligase 1 [Source:HGNC Symbol;Acc:HGNC:17004]",0,{"v":0.047589,"d":"0.05"},"-inf","-inf",1,1,"down","no"]
[21441,0,"chr10","+",75210645,75220970,"ENST00000344036",7,681,"MSTRG.1825","VDAC2","GO:0055085(transmembrane transport);GO:0005739(mitochondrion);GO:0008308(voltage-gated anion channel activity);GO:0098656(anion transmembrane transport);GO:1903959(regulation of anion transmembrane transport);GO:0005741(mitochondrial outer membrane);GO:0006810(transport);GO:0005634(nucleus);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0000166(nucleotide binding);GO:0006811(ion transport);GO:0005515(protein binding);GO:0070062(extracellular exosome);GO:0042645(mitochondrial nucleoid);GO:0015288(porin activity);GO:0046930(pore complex);GO:0006820(anion transport);GO:0032272(negative regulation of protein polymerization);GO:2001243(negative regulation of intrinsic apoptotic signaling pathway);GO:0005743(mitochondrial inner membrane);GO:0008021(synaptic vesicle);GO:0043209(myelin sheath)","04020(Calcium signaling pathway);04022(cGMP - PKG signaling pathway);04216(Ferroptosis);04217(Necroptosis);04218(Cellular senescence);04621(NOD-like receptor signaling pathway);04979(Cholesterol metabolism);05012(Parkinson's disease);05016(Huntington's disease);05166(HTLV-I infection)","NA","NA","voltage dependent anion channel 2 [Source:HGNC Symbol;Acc:HGNC:12672]",{"v":0.027173,"d":"0.03"},0,"inf","inf",1,1,"up","no"]
[187459,0,"chr8","-",133262060,133264992,"ENST00000523931",2,554,"MSTRG.14586","NDRG1","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0015630(microtubule cytoskeleton);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0048471(perinuclear region of cytoplasm);GO:0005874(microtubule);GO:0008017(microtubule binding);GO:0005813(centrosome);GO:0005815(microtubule organizing center);GO:0045296(cadherin binding);GO:0070062(extracellular exosome);GO:0042127(regulation of cell proliferation);GO:0055038(recycling endosome membrane);GO:0032287(peripheral nervous system myelin maintenance);GO:0045576(mast cell activation);GO:0042981(regulation of apoptotic process);GO:0030330(DNA damage response, signal transduction by p53 class mediator);GO:0071456(cellular response to hypoxia);GO:0017137(Rab GTPase binding);GO:0043015(gamma-tubulin binding);GO:0005913(cell-cell adherens junction);GO:0010038(response to metal ion);GO:0090232(positive regulation of spindle checkpoint);GO:0008285(negative regulation of cell proliferation);GO:0043209(myelin sheath)","NA","NA","NA","N-myc downstream regulated 1 [Source:HGNC Symbol;Acc:HGNC:7679]",{"v":0.059462,"d":"0.06"},{"v":0.042562,"d":"0.04"},{"v":1.39706780696396,"d":"1.40"},{"v":0.482402043937519,"d":"0.48"},1,1,"up","no"]
[90902,0,"chr18","+",12686653,12724520,"ENST00000586445",6,646,"MSTRG.7434","PSMG2","GO:0005634(nucleus);GO:0005515(protein binding);GO:0005829(cytosol);GO:0043248(proteasome assembly);GO:0000502(proteasome complex);GO:0007094(mitotic spindle assembly checkpoint);GO:0043066(negative regulation of apoptotic process);GO:0051726(regulation of cell cycle)","NA","NA","NA","proteasome assembly chaperone 2 [Source:HGNC Symbol;Acc:HGNC:24929]",{"v":0.000139,"d":"0.00"},0,"inf","inf",1,1,"up","no"]
[22935,0,"chr10","-",101022615,101030130,"ENST00000476306",2,1591,"ENSG00000186862","PDZD7","GO:0005634(nucleus);GO:0042995(cell projection);GO:0005615(extracellular space);GO:0005515(protein binding);GO:0005929(cilium);GO:0042803(protein homodimerization activity);GO:0046982(protein heterodimerization activity);GO:0045184(establishment of protein localization);GO:0050910(detection of mechanical stimulus involved in sensory perception of sound);GO:0060088(auditory receptor cell stereocilium organization);GO:0060117(auditory receptor cell development);GO:0002141(stereocilia ankle link);GO:1990696(USH2 complex)","NA","NA","NA","PDZ domain containing 7 [Source:HGNC Symbol;Acc:HGNC:26257]",{"v":0.0124,"d":"0.01"},0,"inf","inf",1,1,"up","no"]
[63487,0,"chr15","+",64151741,64154762,"ENST00000560607",6,1182,"MSTRG.5174","SNX22","GO:0006810(transport);GO:0016020(membrane);GO:0015031(protein transport);GO:0030659(cytoplasmic vesicle membrane);GO:0031410(cytoplasmic vesicle);GO:0035091(phosphatidylinositol binding);GO:0008289(lipid binding)","NA","NA","NA","sorting nexin 22 [Source:HGNC Symbol;Acc:HGNC:16315]",{"v":0.780719,"d":"0.78"},{"v":0.666596,"d":"0.67"},{"v":1.17120264748063,"d":"1.17"},{"v":0.227990719922147,"d":"0.23"},1,1,"up","no"]
[100549,0,"chr19","+",36605328,36607811,"ENST00000463910",2,663,"ENSG00000161298","ZNF382","GO:0003676(nucleic acid binding);GO:0006355(regulation of transcription, DNA-templated);GO:0005622(intracellular);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0044212(transcription regulatory region DNA binding)","NA","NA","NA","zinc finger protein 382 [Source:HGNC Symbol;Acc:HGNC:17409]",0,0,1,0,1,1,"no","no"]
[129514,0,"chr22","+",24270883,24414773,"ENST00000541492",15,3525,"MSTRG.10311","SPECC1L","GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0051301(cell division);GO:0015629(actin cytoskeleton);GO:0005856(cytoskeleton);GO:0007049(cell cycle);GO:0005921(gap junction);GO:0030054(cell junction);GO:0005819(spindle);GO:0007155(cell adhesion)","NA","NA","NA","sperm antigen with calponin homology and coiled-coil domains 1 like [Source:HGNC Symbol;Acc:HGNC:29022]",0,{"v":0.144979,"d":"0.14"},"-inf","-inf",1,1,"down","no"]
[193526,0,"chr9","+",127612361,127613751,"ENST00000476182",2,566,"MSTRG.14973","STXBP1","GO:0016192(vesicle-mediated transport);GO:0006904(vesicle docking involved in exocytosis);GO:0003723(RNA binding);GO:0006810(transport);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0015031(protein transport);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0005739(mitochondrion);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0070062(extracellular exosome);GO:0000149(SNARE binding);GO:0043234(protein complex);GO:0042802(identical protein binding);GO:0019905(syntaxin binding);GO:0070527(platelet aggregation);GO:0031091(platelet alpha granule);GO:0014047(glutamate secretion);GO:0007269(neurotransmitter secretion);GO:0017075(syntaxin-1 binding);GO:0072659(protein localization to plasma membrane);GO:0002576(platelet degranulation);GO:0016188(synaptic vesicle maturation);GO:0031630(regulation of synaptic vesicle fusion to presynaptic active zone membrane);GO:0019901(protein kinase binding);GO:0019904(protein domain specific binding);GO:0043274(phospholipase binding);GO:0047485(protein N-terminus binding);GO:0003006(developmental process involved in reproduction);GO:0006887(exocytosis);GO:0007274(neuromuscular synaptic transmission);GO:0007412(axon target recognition);GO:0010807(regulation of synaptic vesicle priming);GO:0031333(negative regulation of protein complex assembly);GO:0031338(regulation of vesicle fusion);GO:0032229(negative regulation of synaptic transmission, GABAergic);GO:0032355(response to estradiol);GO:0035542(regulation of SNARE complex assembly);GO:0043306(positive regulation of mast cell degranulation);GO:0043524(negative regulation of neuron apoptotic process);GO:0045921(positive regulation of exocytosis);GO:0045956(positive regulation of calcium ion-dependent exocytosis);GO:0050821(protein stabilization);GO:0060292(long term synaptic depression);GO:0099525(presynaptic dense core vesicle exocytosis);GO:0106022(positive regulation of vesicle docking);GO:1903296(positive regulation of glutamate secretion, neurotransmission);GO:0005634(nucleus);GO:0005856(cytoskeleton);GO:0030424(axon);GO:0043195(terminal bouton);GO:0043209(myelin sheath);GO:0048471(perinuclear region of cytoplasm);GO:0048787(presynaptic active zone membrane);GO:0098793(presynapse);GO:0098794(postsynapse)","04721(Synaptic vesicle cycle)","NA","NA","syntaxin binding protein 1 [Source:HGNC Symbol;Acc:HGNC:11444]",0,{"v":0.092197,"d":"0.09"},"-inf","-inf",1,1,"down","no"]
[127244,0,"chr21","+",39380394,39392046,"ENST00000487869",3,537,"ENSG00000182093","WRB","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0071816(tail-anchored membrane protein insertion into ER membrane);GO:0005634(nucleus)","NA","NA","NA","tryptophan rich basic protein [Source:HGNC Symbol;Acc:HGNC:12790]",{"v":0.086095,"d":"0.09"},0,"inf","inf",1,1,"up","no"]
[78897,0,"chr17","+",7572828,7577110,"ENST00000585024",6,577,"MSTRG.6423","EIF4A1","GO:0003676(nucleic acid binding);GO:0005524(ATP binding);GO:0000166(nucleotide binding);GO:0016787(hydrolase activity);GO:0004386(helicase activity);GO:0003723(RNA binding);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0003743(translation initiation factor activity);GO:0006412(translation);GO:0006413(translational initiation);GO:0005515(protein binding);GO:0003729(mRNA binding);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0004004(ATP-dependent RNA helicase activity);GO:0010501(RNA secondary structure unwinding);GO:0000289(nuclear-transcribed mRNA poly(A) tail shortening);GO:0016032(viral process);GO:0031012(extracellular matrix);GO:0010468(regulation of gene expression);GO:0003725(double-stranded RNA binding);GO:0016281(eukaryotic translation initiation factor 4F complex);GO:0008135(translation factor activity, RNA binding);GO:0000339(RNA cap binding)","03013(RNA transport)","NA","NA","eukaryotic translation initiation factor 4A1 [Source:HGNC Symbol;Acc:HGNC:3282]",{"v":0.313267,"d":"0.31"},{"v":0.627299,"d":"0.63"},{"v":0.499390242930405,"d":"0.50"},{"v":-1.00176046067256,"d":"-1.00"},1,1,"down","no"]
[128032,0,"chr21","+",46220269,46222341,"ENST00000418029",2,788,"ENSG00000223901","AP001469.1","NA","NA","NA","NA","NA",{"v":0.067411,"d":"0.07"},0,"inf","inf",1,1,"up","no"]
[3415,0,"chr1","+",28518266,28536875,"ENST00000411533",10,1169,"MSTRG.326","RCC1","GO:0005654(nucleoplasm);GO:0031965(nuclear membrane);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0003677(DNA binding);GO:0051301(cell division);GO:0000790(nuclear chromatin);GO:0043547(positive regulation of GTPase activity);GO:0005515(protein binding);GO:0007049(cell cycle);GO:0005085(guanyl-nucleotide exchange factor activity);GO:0007059(chromosome segregation);GO:0003682(chromatin binding);GO:0007052(mitotic spindle organization);GO:0042393(histone binding);GO:0043234(protein complex);GO:0000794(condensed nuclear chromosome);GO:0046982(protein heterodimerization activity);GO:0016032(viral process);GO:0051225(spindle assembly);GO:0007088(regulation of mitotic nuclear division);GO:0031492(nucleosomal DNA binding);GO:0051290(protein heterotetramerization);GO:0000082(G1/S transition of mitotic cell cycle);GO:0043199(sulfate binding);GO:0005087(Ran guanyl-nucleotide exchange factor activity);GO:0008536(Ran GTPase binding);GO:0031491(nucleosome binding)","NA","NA","NA","regulator of chromosome condensation 1 [Source:HGNC Symbol;Acc:HGNC:1913]",{"v":0.503615,"d":"0.50"},{"v":0.346475,"d":"0.35"},{"v":1.45353921639368,"d":"1.45"},{"v":0.539569995817769,"d":"0.54"},1,1,"up","no"]
[169671,0,"chr6","+",138822747,138823799,"ENST00000449542",1,1053,"ENSG00000225415","CCRL1P1","NA","NA","NA","NA","C-C motif chemokine receptor like 1 pseudogene 1 [Source:HGNC Symbol;Acc:HGNC:21142]",0,0,1,0,1,1,"no","no"]
[56657,0,"chr14","+",73788965,73803270,"ENST00000553470",2,538,"MSTRG.4519","AC005520.2","NA","NA","NA","NA","NA",{"v":0.148103,"d":"0.15"},{"v":0.193887,"d":"0.19"},{"v":0.76386245596662,"d":"0.76"},{"v":-0.388615210499631,"d":"-0.39"},1,1,"down","no"]
[61948,0,"chr15","+",44519637,44525947,"ENST00000559175",2,3609,"MSTRG.5042","CTDSPL2","GO:0005654(nucleoplasm);GO:0016787(hydrolase activity);GO:0016791(phosphatase activity);GO:0004721(phosphoprotein phosphatase activity);GO:0006470(protein dephosphorylation);GO:0030514(negative regulation of BMP signaling pathway);GO:0046827(positive regulation of protein export from nucleus);GO:0005634(nucleus)","NA","NA","NA","CTD small phosphatase like 2 [Source:HGNC Symbol;Acc:HGNC:26936]",{"v":0.064039,"d":"0.06"},{"v":0.014126,"d":"0.01"},{"v":4.53341356364151,"d":"4.53"},{"v":2.18059777803377,"d":"2.18"},1,1,"up","no"]
[144355,0,"chr3","+",195658093,195664288,"ENST00000425425",4,525,"ENSG00000242086","LINC00969","NA","NA","NA","NA","long intergenic non-protein coding RNA 969 [Source:HGNC Symbol;Acc:HGNC:48729]",{"v":0.106213,"d":"0.11"},0,"inf","inf",1,1,"up","no"]
[159020,0,"chr5","-",139476345,139481461,"ENST00000503287",5,948,"MSTRG.12367","TMEM173","GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0000166(nucleotide binding);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005739(mitochondrion);GO:0042803(protein homodimerization activity);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0006915(apoptotic process);GO:0048471(perinuclear region of cytoplasm);GO:0005741(mitochondrial outer membrane);GO:0002376(immune system process);GO:0045087(innate immune response);GO:0042802(identical protein binding);GO:0051607(defense response to virus);GO:0019901(protein kinase binding);GO:0043312(neutrophil degranulation);GO:0002218(activation of innate immune response);GO:0032481(positive regulation of type I interferon production);GO:0030667(secretory granule membrane);GO:0032092(positive regulation of protein binding);GO:0030659(cytoplasmic vesicle membrane);GO:0008134(transcription factor binding);GO:0033160(positive regulation of protein import into nucleus, translocation);GO:0042993(positive regulation of transcription factor import into nucleus);GO:0071407(cellular response to organic cyclic compound);GO:0071360(cellular response to exogenous dsRNA);GO:0032479(regulation of type I interferon production);GO:0002230(positive regulation of defense response to virus by host);GO:0031625(ubiquitin protein ligase binding);GO:0035438(cyclic-di-GMP binding);GO:0061507(cyclic-GMP-AMP binding);GO:0032608(interferon-beta production);GO:0035458(cellular response to interferon-beta);GO:0005777(peroxisome);GO:0005794(Golgi apparatus)","04621(NOD-like receptor signaling pathway);04622(RIG-I-like receptor signaling pathway);04623(Cytosolic DNA-sensing pathway)","NA","NA","transmembrane protein 173 [Source:HGNC Symbol;Acc:HGNC:27962]",{"v":0.065603,"d":"0.07"},{"v":0.063432,"d":"0.06"},{"v":1.03422562744356,"d":"1.03"},{"v":0.0485509594288677,"d":"0.05"},1,1,"up","no"]
[2232,0,"chr1","-",19232928,19238804,"ENST00000641089",6,570,"MSTRG.208","EMC1","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0072546(ER membrane protein complex);GO:0034975(protein folding in endoplasmic reticulum);GO:0005783(endoplasmic reticulum)","NA","NA","NA","ER membrane protein complex subunit 1 [Source:HGNC Symbol;Acc:HGNC:28957]",{"v":0.037605,"d":"0.04"},0,"inf","inf",1,1,"up","no"]
[31572,0,"chr11","+",66257620,66261948,"ENST00000526758",3,594,"ENSG00000174996","KLC2","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0003777(microtubule motor activity);GO:0005871(kinesin complex);GO:0005856(cytoskeleton);GO:0005874(microtubule);GO:0005829(cytosol);GO:0045296(cadherin binding);GO:0006890(retrograde vesicle-mediated transport, Golgi to ER);GO:0005515(protein binding);GO:0007018(microtubule-based movement);GO:0019886(antigen processing and presentation of exogenous peptide antigen via MHC class II);GO:0019894(kinesin binding);GO:0043234(protein complex);GO:0016938(kinesin I complex)","05132(Salmonella infection)","NA","NA","kinesin light chain 2 [Source:HGNC Symbol;Acc:HGNC:20716]",0,0,1,0,1,1,"no","no"]
[96911,0,"chr19","+",11946754,11950773,"ENST00000482090",3,3113,"ENSG00000196757","ZNF700","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0005622(intracellular)","NA","NA","NA","zinc finger protein 700 [Source:HGNC Symbol;Acc:HGNC:25292]",{"v":0.03524,"d":"0.04"},{"v":0.017268,"d":"0.02"},{"v":2.04076905258281,"d":"2.04"},{"v":1.02911292634632,"d":"1.03"},1,1,"up","no"]
[62767,0,"chr15","-",55289888,55319110,"ENST00000561545",3,830,"MSTRG.5100","RAB27A","GO:0016020(membrane);GO:0005525(GTP binding);GO:0000166(nucleotide binding);GO:0003924(GTPase activity);GO:0005515(protein binding);GO:0042470(melanosome);GO:0045202(synapse);GO:0005764(lysosome);GO:0030425(dendrite);GO:0005576(extracellular region);GO:0006887(exocytosis);GO:0005768(endosome);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0010628(positive regulation of gene expression);GO:0019904(protein domain specific binding);GO:0031489(myosin V binding);GO:0006605(protein targeting);GO:0007596(blood coagulation);GO:0016192(vesicle-mediated transport);GO:0030318(melanocyte differentiation);GO:0032400(melanosome localization);GO:0032402(melanosome transport);GO:0043316(cytotoxic T cell degranulation);GO:0043320(natural killer cell degranulation);GO:0043473(pigmentation);GO:0051875(pigment granule localization);GO:0051904(pigment granule transport);GO:0001750(photoreceptor outer segment);GO:0005794(Golgi apparatus);GO:0016324(apical plasma membrane);GO:0030141(secretory granule);GO:0030667(secretory granule membrane);GO:0033093(Weibel-Palade body);GO:0061024(membrane organization);GO:0005770(late endosome);GO:0043312(neutrophil degranulation);GO:0019003(GDP binding);GO:0045921(positive regulation of exocytosis);GO:0071985(multivesicular body sorting pathway);GO:0032585(multivesicular body membrane);GO:0050766(positive regulation of phagocytosis);GO:0035580(specific granule lumen);GO:0048489(synaptic vesicle transport);GO:1903307(positive regulation of regulated secretory pathway);GO:0019882(antigen processing and presentation);GO:0070382(exocytic vesicle);GO:1903428(positive regulation of reactive oxygen species biosynthetic process);GO:0033162(melanosome membrane);GO:0036257(multivesicular body organization);GO:0097278(complement-dependent cytotoxicity);GO:1903435(positive regulation of constitutive secretory pathway);GO:1990182(exosomal secretion)","NA","NA","NA","RAB27A, member RAS oncogene family [Source:HGNC Symbol;Acc:HGNC:9766]",{"v":0.165576,"d":"0.17"},{"v":0.119266,"d":"0.12"},{"v":1.3882917176731,"d":"1.39"},{"v":0.473310749054663,"d":"0.47"},1,1,"up","no"]
[89550,0,"chr17","-",81904898,81911418,"ENST00000576343",12,1006,"MSTRG.7341","PCYT2","GO:0016740(transferase activity);GO:0003824(catalytic activity);GO:0006629(lipid metabolic process);GO:0009058(biosynthetic process);GO:0006646(phosphatidylethanolamine biosynthetic process);GO:0008654(phospholipid biosynthetic process);GO:0016779(nucleotidyltransferase activity);GO:0005575(cellular_component);GO:0005789(endoplasmic reticulum membrane);GO:0004306(ethanolamine-phosphate cytidylyltransferase activity)","00564(Glycerophospholipid metabolism);00440(Phosphonate and phosphinate metabolism)","K00967","EC:2.7.7.14","phosphate cytidylyltransferase 2, ethanolamine [Source:HGNC Symbol;Acc:HGNC:8756]",{"v":0.401693,"d":"0.40"},0,"inf","inf",1,1,"up","no"]
[185542,0,"chr8","-",93134095,93166850,"ENST00000521906",3,588,"ENSG00000279847","C8orf87","NA","NA","NA","NA","chromosome 8 open reading frame 87 [Source:HGNC Symbol;Acc:HGNC:42974]",0,0,1,0,1,1,"no","no"]
[100806,0,"chr19","-",37699820,37719723,"ENST00000591664",4,741,"ENSG00000198182","ZNF607","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0005622(intracellular);GO:0005515(protein binding);GO:0003700(transcription factor activity, sequence-specific DNA binding)","NA","NA","NA","zinc finger protein 607 [Source:HGNC Symbol;Acc:HGNC:28192]",{"v":0.550173,"d":"0.55"},0,"inf","inf",1,1,"up","no"]
[83411,0,"chr17","-",41976452,41982321,"ENST00000587727",3,449,"MSTRG.6815","DNAJC7","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0032781(positive regulation of ATPase activity);GO:0070062(extracellular exosome);GO:1900034(regulation of cellular response to heat);GO:0006457(protein folding);GO:0001671(ATPase activator activity);GO:0031072(heat shock protein binding);GO:0070389(chaperone cofactor-dependent protein refolding)","NA","NA","NA","DnaJ heat shock protein family (Hsp40) member C7 [Source:HGNC Symbol;Acc:HGNC:12392]",0,{"v":0.132241,"d":"0.13"},"-inf","-inf",1,1,"down","no"]
[170625,0,"chr6","+",160010338,160024693,"ENST00000464636",2,570,"MSTRG.13400","IGF2R","GO:0006810(transport);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005794(Golgi apparatus);GO:0005215(transporter activity);GO:0005765(lysosomal membrane);GO:0005515(protein binding);GO:0005925(focal adhesion);GO:0005764(lysosome);GO:0005886(plasma membrane);GO:0042802(identical protein binding);GO:0070062(extracellular exosome);GO:0061024(membrane organization);GO:0005802(trans-Golgi network);GO:0005769(early endosome);GO:0005887(integral component of plasma membrane);GO:0043312(neutrophil degranulation);GO:0007165(signal transduction);GO:0032588(trans-Golgi network membrane);GO:0004872(receptor activity);GO:0009986(cell surface);GO:0030667(secretory granule membrane);GO:0030133(transport vesicle);GO:0051219(phosphoprotein binding);GO:0030139(endocytic vesicle);GO:0030665(clathrin-coated vesicle membrane);GO:0006898(receptor-mediated endocytosis);GO:0005768(endosome);GO:0005010(insulin-like growth factor-activated receptor activity);GO:0030140(trans-Golgi network transport vesicle);GO:0005770(late endosome);GO:0001965(G-protein alpha-subunit binding);GO:0001972(retinoic acid binding);GO:0004930(G-protein coupled receptor activity);GO:0005520(insulin-like growth factor binding);GO:0005537(mannose binding);GO:0019899(enzyme binding);GO:0031995(insulin-like growth factor II binding);GO:0001889(liver development);GO:0007186(G-protein coupled receptor signaling pathway);GO:0007283(spermatogenesis);GO:0009791(post-embryonic development);GO:0031100(animal organ regeneration);GO:0032526(response to retinoic acid);GO:0042981(regulation of apoptotic process);GO:0043065(positive regulation of apoptotic process);GO:0048009(insulin-like growth factor receptor signaling pathway);GO:0005615(extracellular space);GO:0005634(nucleus);GO:0005641(nuclear envelope lumen);GO:0030118(clathrin coat);GO:0048471(perinuclear region of cytoplasm)","04144(Endocytosis);04142(Lysosome)","NA","NA","insulin like growth factor 2 receptor [Source:HGNC Symbol;Acc:HGNC:5467]",{"v":0.190463,"d":"0.19"},0,"inf","inf",1,1,"up","no"]
[162471,0,"chr6","+",3150014,3153046,"ENST00000464040",2,691,"MSTRG.12633","BPHL","GO:0016787(hydrolase activity);GO:0005739(mitochondrion);GO:0070062(extracellular exosome);GO:0006805(xenobiotic metabolic process);GO:0005741(mitochondrial outer membrane);GO:0006520(cellular amino acid metabolic process);GO:0009636(response to toxic substance);GO:0047658(alpha-amino-acid esterase activity)","NA","NA","NA","biphenyl hydrolase like [Source:HGNC Symbol;Acc:HGNC:1094]",{"v":0.088448,"d":"0.09"},0,"inf","inf",1,1,"up","no"]
[181041,0,"chr8","+",8228600,8240030,"ENST00000588728",6,1030,"ENSG00000173295","FAM86B3P","NA","NA","NA","NA","family with sequence similarity 86 member B3, pseudogene [Source:HGNC Symbol;Acc:HGNC:44371]",{"v":0.230123,"d":"0.23"},0,"inf","inf",1,1,"up","no"]
[97091,0,"chr19","-",12677291,12681332,"ENST00000597152",6,605,"MSTRG.7846","DHPS","GO:0008612(peptidyl-lysine modification to peptidyl-hypusine);GO:0016740(transferase activity);GO:0005515(protein binding);GO:0034038(deoxyhypusine synthase activity);GO:0042102(positive regulation of T cell proliferation);GO:0042593(glucose homeostasis);GO:0046203(spermidine catabolic process);GO:0051289(protein homotetramerization);GO:0042802(identical protein binding);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0006412(translation);GO:0008284(positive regulation of cell proliferation);GO:0008216(spermidine metabolic process)","NA","NA","NA","deoxyhypusine synthase [Source:HGNC Symbol;Acc:HGNC:2869]",0,{"v":5.8E-5,"d":"0.00"},"-inf","-inf",1,1,"down","no"]
[61124,0,"chr15","+",40312615,40316634,"ENST00000559030",1,4020,"ENSG00000259198","AC020658.2","NA","NA","NA","NA","NA",0,0,1,0,1,1,"no","no"]
[101127,0,"chr19","-",38889087,38894277,"ENST00000381766",6,848,"MSTRG.8122","SIRT2","GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0005730(nucleolus);GO:0005829(cytosol);GO:0004407(histone deacetylase activity);GO:0016787(hydrolase activity);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0051301(cell division);GO:0005886(plasma membrane);GO:0005694(chromosome);GO:0070403(NAD+ binding);GO:0034979(NAD-dependent protein deacetylase activity);GO:0006476(protein deacetylation);GO:0017136(NAD-dependent histone deacetylase activity);GO:0005856(cytoskeleton);GO:0042995(cell projection);GO:0005515(protein binding);GO:0007049(cell cycle);GO:0048471(perinuclear region of cytoplasm);GO:0051321(meiotic cell cycle);GO:0007399(nervous system development);GO:0030154(cell differentiation);GO:0005874(microtubule);GO:0006914(autophagy);GO:0002376(immune system process);GO:0045087(innate immune response);GO:0005813(centrosome);GO:0005815(microtubule organizing center);GO:0005819(spindle);GO:0030496(midbody);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0030426(growth cone);GO:0043204(perikaryon);GO:0005814(centriole);GO:0008285(negative regulation of cell proliferation);GO:0003682(chromatin binding);GO:0071219(cellular response to molecule of bacterial origin);GO:0021762(substantia nigra development);GO:0043130(ubiquitin binding);GO:0034599(cellular response to oxidative stress);GO:0008134(transcription factor binding);GO:0045892(negative regulation of transcription, DNA-templated);GO:0043161(proteasome-mediated ubiquitin-dependent protein catabolic process);GO:0045599(negative regulation of fat cell differentiation);GO:0051726(regulation of cell cycle);GO:0051775(response to redox state);GO:0014065(phosphatidylinositol 3-kinase signaling);GO:0042177(negative regulation of protein catabolic process);GO:0006342(chromatin silencing);GO:0051781(positive regulation of cell division);GO:0070932(histone H3 deacetylation);GO:0071456(cellular response to hypoxia);GO:0033558(protein deacetylase activity);GO:0042826(histone deacetylase binding);GO:0000183(chromatin silencing at rDNA);GO:0005677(chromatin silencing complex);GO:1900425(negative regulation of defense response to bacterium);GO:0042325(regulation of phosphorylation);GO:0043388(positive regulation of DNA binding);GO:0032436(positive regulation of proteasomal ubiquitin-dependent protein catabolic process);GO:0072686(mitotic spindle);GO:0031641(regulation of myelination);GO:0043209(myelin sheath);GO:0035035(histone acetyltransferase binding);GO:0043491(protein kinase B signaling);GO:2000378(negative regulation of reactive oxygen species metabolic process);GO:0006471(protein ADP-ribosylation);GO:0005720(nuclear heterochromatin);GO:0010507(negative regulation of autophagy);GO:0035729(cellular response to hepatocyte growth factor stimulus);GO:0033010(paranodal junction);GO:0044242(cellular lipid catabolic process);GO:0016575(histone deacetylation);GO:0071872(cellular response to epinephrine stimulus);GO:0061428(negative regulation of transcription from RNA polymerase II promoter in response to hypoxia);GO:0007096(regulation of exit from mitosis);GO:0072687(meiotic spindle);GO:0022011(myelination in peripheral nervous system);GO:0097386(glial cell projection);GO:0010801(negative regulation of peptidyl-threonine phosphorylation);GO:0033270(paranode region of axon);GO:0044224(juxtaparanode region of axon);GO:1900119(positive regulation of execution phase of apoptosis);GO:0070933(histone H4 deacetylation);GO:0043220(Schmidt-Lanterman incisure);GO:0045836(positive regulation of meiotic nuclear division);GO:0042903(tubulin deacetylase activity);GO:0046970(NAD-dependent histone deacetylase activity (H4-K16 specific));GO:0048487(beta-tubulin binding);GO:0006348(chromatin silencing at telomere);GO:0016458(gene silencing);GO:0034983(peptidyl-lysine deacetylation);GO:0045598(regulation of fat cell differentiation);GO:0045843(negative regulation of striated muscle tissue development);GO:0048012(hepatocyte growth factor receptor signaling pathway);GO:0051987(positive regulation of attachment of spindle microtubules to kinetochore);GO:0061433(cellular response to caloric restriction);GO:0070446(negative regulation of oligodendrocyte progenitor proliferation);GO:0090042(tubulin deacetylation);GO:1900195(positive regulation of oocyte maturation);GO:1900226(negative regulation of NLRP3 inflammasome complex assembly);GO:1901026(ripoptosome assembly involved in necroptotic process);GO:2000777(positive regulation of proteasomal ubiquitin-dependent protein catabolic process involved in cellular response to hypoxia);GO:0000781(chromosome, telomeric region);GO:0005739(mitochondrion);GO:0043219(lateral loop)","NA","NA","NA","sirtuin 2 [Source:HGNC Symbol;Acc:HGNC:10886]",{"v":0.530688,"d":"0.53"},0,"inf","inf",1,1,"up","no"]
[100686,0,"chr19","+",37312878,37317142,"ENST00000587570",2,583,"ENSG00000181666","HKR1","GO:0003676(nucleic acid binding);GO:0006355(regulation of transcription, DNA-templated);GO:0005622(intracellular);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0007275(multicellular organism development)","NA","NA","NA","HKR1, GLI-Kruppel zinc finger family member [Source:HGNC Symbol;Acc:HGNC:4928]",0,{"v":0.05204,"d":"0.05"},"-inf","-inf",1,1,"down","no"]
[98734,0,"chr19","-",18910555,18919365,"ENST00000597646",3,868,"MSTRG.8008","COPE","GO:0006810(transport);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0015031(protein transport);GO:0005794(Golgi apparatus);GO:0005654(nucleoplasm);GO:0005198(structural molecule activity);GO:0005515(protein binding);GO:0000139(Golgi membrane);GO:0006890(retrograde vesicle-mediated transport, Golgi to ER);GO:0031410(cytoplasmic vesicle);GO:0016192(vesicle-mediated transport);GO:0006891(intra-Golgi vesicle-mediated transport);GO:0030663(COPI-coated vesicle membrane);GO:0005789(endoplasmic reticulum membrane);GO:0005829(cytosol);GO:0006888(ER to Golgi vesicle-mediated transport);GO:0030133(transport vesicle);GO:0030126(COPI vesicle coat);GO:0030137(COPI-coated vesicle)","NA","NA","NA","coatomer protein complex subunit epsilon [Source:HGNC Symbol;Acc:HGNC:2234]",{"v":8.1e-05,"d":"0.00"},{"v":0.199529,"d":"0.20"},{"v":4.05956026442272E-4,"d":"0.00"},{"v":-11.2663889178274,"d":"-11.27"},1,1,"down","no"]
[600,0,"chr1","-",1756588,1778419,"ENST00000492768",5,859,"MSTRG.65","NADK","GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0008152(metabolic process);GO:0003951(NAD+ kinase activity);GO:0005829(cytosol);GO:0019674(NAD metabolic process);GO:0006741(NADP biosynthetic process);GO:0005515(protein binding);GO:0046034(ATP metabolic process)","00760(Nicotinate and nicotinamide metabolism)","NA","NA","NAD kinase [Source:HGNC Symbol;Acc:HGNC:29831]",{"v":0.861618,"d":"0.86"},{"v":0.764686,"d":"0.76"},{"v":1.12676052654292,"d":"1.13"},{"v":0.172180928216423,"d":"0.17"},1,1,"up","no"]
[112821,0,"chr2","-",99284238,99301176,"ENST00000308528",7,990,"MSTRG.9000","LYG1","GO:0016787(hydrolase activity);GO:0008152(metabolic process);GO:0005576(extracellular region);GO:0016798(hydrolase activity, acting on glycosyl bonds);GO:0003796(lysozyme activity);GO:0009253(peptidoglycan catabolic process);GO:0016998(cell wall macromolecule catabolic process)","NA","NA","NA","lysozyme g1 [Source:HGNC Symbol;Acc:HGNC:27014]",{"v":0.033757,"d":"0.03"},0,"inf","inf",1,1,"up","no"]
[27622,0,"chr11","-",30536059,30586872,"ENST00000528686",3,497,"ENSG00000066382","MPPED2","GO:0046872(metal ion binding);GO:0016787(hydrolase activity);GO:0005515(protein binding);GO:0007399(nervous system development)","NA","NA","NA","metallophosphoesterase domain containing 2 [Source:HGNC Symbol;Acc:HGNC:1180]",{"v":0.00019,"d":"0.00"},0,"inf","inf",1,1,"up","no"]
[109528,0,"chr2","-",47945256,48164934,"ENST00000587616",11,1353,"ENSG00000230773","AC092650.1","NA","NA","NA","NA","NA",{"v":0.00598,"d":"0.01"},0,"inf","inf",1,1,"up","no"]
[75522,0,"chr16","+",72108630,72109756,"ENST00000569952",2,638,"MSTRG.6118","DHX38","GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0006397(mRNA processing);GO:0008380(RNA splicing);GO:0005634(nucleus);GO:0016020(membrane);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0016787(hydrolase activity);GO:0004386(helicase activity);GO:0005515(protein binding);GO:0005681(spliceosomal complex);GO:0005737(cytoplasm);GO:0005654(nucleoplasm);GO:0004004(ATP-dependent RNA helicase activity);GO:0000398(mRNA splicing, via spliceosome);GO:0006369(termination of RNA polymerase II transcription);GO:0006405(RNA export from nucleus);GO:0031124(mRNA 3'-end processing);GO:0006406(mRNA export from nucleus);GO:0071013(catalytic step 2 spliceosome)","03040(Spliceosome)","NA","NA","DEAH-box helicase 38 [Source:HGNC Symbol;Acc:HGNC:17211]",{"v":0.162887,"d":"0.16"},{"v":0.047917,"d":"0.05"},{"v":3.3993572218628,"d":"3.40"},{"v":1.76526197562791,"d":"1.77"},1,1,"up","no"]
[191987,0,"chr9","-",95759231,95875480,"ENST00000433656",4,1040,"ENSG00000175611","LINC00476","NA","NA","NA","NA","long intergenic non-protein coding RNA 476 [Source:HGNC Symbol;Acc:HGNC:27858]",{"v":0.887346,"d":"0.89"},{"v":0.444649,"d":"0.44"},{"v":1.99561002048807,"d":"2.00"},{"v":0.996829818632233,"d":"1.00"},1,1,"up","no"]
[8955,0,"chr1","+",110034626,110038244,"ENST00000489059",2,546,"MSTRG.772","STRIP1","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005515(protein binding);GO:0003674(molecular_function);GO:0070062(extracellular exosome);GO:0022604(regulation of cell morphogenesis);GO:0030866(cortical actin cytoskeleton organization)","NA","NA","NA","striatin interacting protein 1 [Source:HGNC Symbol;Acc:HGNC:25916]",{"v":0.089375,"d":"0.09"},0,"inf","inf",1,1,"up","no"]
[87290,0,"chr17","+",68248075,68254437,"ENST00000579724",6,722,"MSTRG.7154","AMZ2","GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0016787(hydrolase activity);GO:0008233(peptidase activity);GO:0006508(proteolysis);GO:0008237(metallopeptidase activity);GO:0005575(cellular_component)","NA","NA","NA","archaelysin family metallopeptidase 2 [Source:HGNC Symbol;Acc:HGNC:28041]",{"v":0.152485,"d":"0.15"},{"v":0.141269,"d":"0.14"},{"v":1.07939463010285,"d":"1.08"},{"v":0.110222415155027,"d":"0.11"},1,1,"up","no"]
[153044,0,"chr5","+",461630,464728,"ENST00000511015",3,1031,"MSTRG.11953","EXOC3","GO:0006810(transport);GO:0005737(cytoplasm);GO:0015031(protein transport);GO:0006887(exocytosis);GO:0000145(exocyst);GO:0005794(Golgi apparatus);GO:0042995(cell projection);GO:0048471(perinuclear region of cytoplasm);GO:0030496(midbody);GO:0005515(protein binding);GO:0005829(cytosol);GO:0045296(cadherin binding);GO:0030426(growth cone);GO:0000149(SNARE binding);GO:0030667(secretory granule membrane);GO:0051601(exocyst localization)","NA","NA","NA","exocyst complex component 3 [Source:HGNC Symbol;Acc:HGNC:30378]",{"v":0.635763,"d":"0.64"},{"v":1.059223,"d":"1.06"},{"v":0.600216385029404,"d":"0.60"},{"v":-0.73644539194914,"d":"-0.74"},1,1,"down","no"]
[179959,0,"chr7","+",149714781,149720124,"ENST00000486744",4,596,"ENSG00000133619","KRBA1","GO:0003676(nucleic acid binding);GO:0006355(regulation of transcription, DNA-templated);GO:0005622(intracellular);GO:0003674(molecular_function);GO:0008150(biological_process);GO:0005575(cellular_component)","NA","NA","NA","KRAB-A domain containing 1 [Source:HGNC Symbol;Acc:HGNC:22228]",{"v":0.172942,"d":"0.17"},{"v":0.065548,"d":"0.07"},{"v":2.63840239214011,"d":"2.64"},{"v":1.39966461192589,"d":"1.40"},1,1,"up","no"]
[99420,0,"chr19","+",23914919,23944713,"ENST00000575986",4,1522,"ENSG00000213967","ZNF726","GO:0003676(nucleic acid binding);GO:0006355(regulation of transcription, DNA-templated);GO:0005622(intracellular);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding)","NA","NA","NA","zinc finger protein 726 [Source:HGNC Symbol;Acc:HGNC:32462]",0,0,1,0,1,1,"no","no"]
[196564,0,"chrX","+",41334162,41348259,"ENST00000441189",6,1051,"MSTRG.15248","DDX3X","GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016607(nuclear speck);GO:0016020(membrane);GO:0005852(eukaryotic translation initiation factor 3 complex);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0005829(cytosol);GO:0016787(hydrolase activity);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0004386(helicase activity);GO:0032508(DNA duplex unwinding);GO:0003677(DNA binding);GO:0005739(mitochondrion);GO:0005515(protein binding);GO:0006915(apoptotic process);GO:0022627(cytosolic small ribosomal subunit);GO:0016055(Wnt signaling pathway);GO:0005741(mitochondrial outer membrane);GO:0045727(positive regulation of translation);GO:0002376(immune system process);GO:0045087(innate immune response);GO:0042254(ribosome biogenesis);GO:0005576(extracellular region);GO:0005730(nucleolus);GO:0007059(chromosome segregation);GO:0045948(positive regulation of translational initiation);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0045296(cadherin binding);GO:0070062(extracellular exosome);GO:0006417(regulation of translation);GO:0009615(response to virus);GO:0016887(ATPase activity);GO:0043065(positive regulation of apoptotic process);GO:0016032(viral process);GO:0010628(positive regulation of gene expression);GO:0043312(neutrophil degranulation);GO:0017148(negative regulation of translation);GO:0010494(cytoplasmic stress granule);GO:0004003(ATP-dependent DNA helicase activity);GO:0043066(negative regulation of apoptotic process);GO:0008134(transcription factor binding);GO:0030308(negative regulation of cell growth);GO:0008625(extrinsic apoptotic signaling pathway via death domain receptors);GO:0034774(secretory granule lumen);GO:1904813(ficolin-1-rich granule lumen);GO:0030307(positive regulation of cell growth);GO:0035556(intracellular signal transduction);GO:0003924(GTPase activity);GO:0004004(ATP-dependent RNA helicase activity);GO:0008143(poly(A) binding);GO:0008190(eukaryotic initiation factor 4E binding);GO:0017111(nucleoside-triphosphatase activity);GO:0031369(translation initiation factor binding);GO:0033592(RNA strand annealing activity);GO:0035613(RNA stem-loop binding);GO:0043024(ribosomal small subunit binding);GO:0043273(CTPase activity);GO:0048027(mRNA 5'-UTR binding);GO:0010501(RNA secondary structure unwinding);GO:0031333(negative regulation of protein complex assembly);GO:0032728(positive regulation of interferon-beta production);GO:0034063(stress granule assembly);GO:0042256(mature ribosome assembly);GO:0043154(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process);GO:0043280(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process);GO:0045070(positive regulation of viral genome replication);GO:0071243(cellular response to arsenic-containing substance);GO:0071470(cellular response to osmotic stress);GO:0071651(positive regulation of chemokine (C-C motif) ligand 5 production);GO:0097193(intrinsic apoptotic signaling pathway);GO:1900087(positive regulation of G1/S transition of mitotic cell cycle);GO:1903608(protein localization to cytoplasmic stress granule);GO:2001243(negative regulation of intrinsic apoptotic signaling pathway)","04622(RIG-I-like receptor signaling pathway);05203(Viral carcinogenesis);05161(Hepatitis B)","NA","NA","DEAD-box helicase 3, X-linked [Source:HGNC Symbol;Acc:HGNC:2745]",{"v":0.194524,"d":"0.19"},{"v":0.322657,"d":"0.32"},{"v":0.602881697902107,"d":"0.60"},{"v":-0.730053161740994,"d":"-0.73"},1,1,"down","no"]
[11241,0,"chr1","-",153929501,153933265,"ENST00000480340",3,2530,"MSTRG.994","DENND4B","GO:0005794(Golgi apparatus);GO:0005634(nucleus);GO:0043547(positive regulation of GTPase activity);GO:0005085(guanyl-nucleotide exchange factor activity);GO:0005829(cytosol);GO:0017112(Rab guanyl-nucleotide exchange factor activity);GO:0061024(membrane organization);GO:0032483(regulation of Rab protein signal transduction)","NA","NA","NA","DENN domain containing 4B [Source:HGNC Symbol;Acc:HGNC:29044]",{"v":0.176273,"d":"0.18"},{"v":0.634571,"d":"0.63"},{"v":0.277782943122204,"d":"0.28"},{"v":-1.84797007954394,"d":"-1.85"},1,1,"down","no"]
[3066,0,"chr1","-",26296947,26306576,"ENST00000421827",7,728,"MSTRG.279","UBXN11","GO:0005737(cytoplasm);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0043161(proteasome-mediated ubiquitin-dependent protein catabolic process);GO:0043130(ubiquitin binding)","NA","NA","NA","UBX domain protein 11 [Source:HGNC Symbol;Acc:HGNC:30600]",{"v":0.424328,"d":"0.42"},{"v":0.034953,"d":"0.03"},{"v":12.1399593740165,"d":"12.14"},{"v":3.6016916885565,"d":"3.60"},1,1,"up","no"]
[7061,0,"chr1","-",68045962,68051631,"ENST00000370981",4,1973,"MSTRG.635","DIRAS3","GO:0005622(intracellular);GO:0016020(membrane);GO:0005525(GTP binding);GO:0000166(nucleotide binding);GO:0007165(signal transduction);GO:0003924(GTPase activity);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0007264(small GTPase mediated signal transduction);GO:0000079(regulation of cyclin-dependent protein serine/threonine kinase activity);GO:0006349(regulation of gene expression by genetic imprinting)","NA","NA","NA","DIRAS family GTPase 3 [Source:HGNC Symbol;Acc:HGNC:687]",0,{"v":0.051588,"d":"0.05"},"-inf","-inf",1,1,"down","no"]
[54778,0,"chr14","-",49828613,49829264,"ENST00000556882",2,386,"MSTRG.4377","NEMF","GO:0005634(nucleus);GO:0051168(nuclear export)","NA","NA","NA","nuclear export mediator factor [Source:HGNC Symbol;Acc:HGNC:10663]",{"v":0.001246,"d":"0.00"},{"v":0.135744,"d":"0.14"},{"v":0.00917904290429043,"d":"0.01"},{"v":-6.76744055250655,"d":"-6.77"},1,1,"down","no"]
[170818,0,"chr6","-",166412296,166423984,"ENST00000509742",6,1204,"MSTRG.13416","RPS6KA2","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0005654(nucleoplasm);GO:0016740(transferase activity);GO:0000287(magnesium ion binding);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0035556(intracellular signal transduction);GO:0005515(protein binding);GO:0005829(cytosol);GO:0008285(negative regulation of cell proliferation);GO:0043065(positive regulation of apoptotic process);GO:0004712(protein serine/threonine/tyrosine kinase activity);GO:0007165(signal transduction);GO:0045786(negative regulation of cell cycle);GO:0004711(ribosomal protein S6 kinase activity);GO:0001556(oocyte maturation);GO:0002035(brain renin-angiotensin system);GO:0007507(heart development);GO:0010628(positive regulation of gene expression);GO:0010659(cardiac muscle cell apoptotic process);GO:0018105(peptidyl-serine phosphorylation);GO:0045835(negative regulation of meiotic nuclear division);GO:0060047(heart contraction);GO:0070613(regulation of protein processing);GO:0071322(cellular response to carbohydrate stimulus);GO:0005819(spindle);GO:0005840(ribosome)","04010(MAPK signaling pathway);04150(mTOR signaling pathway);04114(Oocyte meiosis);04914(Progesterone-mediated oocyte maturation);04720(Long-term potentiation);04722(Neurotrophin signaling pathway);04931(Insulin resistance)","NA","NA","ribosomal protein S6 kinase A2 [Source:HGNC Symbol;Acc:HGNC:10431]",{"v":0.049095,"d":"0.05"},0,"inf","inf",1,1,"up","no"]
[45392,0,"chr12","-",95517276,95548844,"ENST00000393091",6,3161,"ENSG00000136014","USP44","GO:0005634(nucleus);GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0016579(protein deubiquitination);GO:0016787(hydrolase activity);GO:0051301(cell division);GO:0008233(peptidase activity);GO:0008234(cysteine-type peptidase activity);GO:0006508(proteolysis);GO:0007049(cell cycle);GO:0006511(ubiquitin-dependent protein catabolic process);GO:0036459(thiol-dependent ubiquitinyl hydrolase activity);GO:0005515(protein binding);GO:0005654(nucleoplasm);GO:0004843(thiol-dependent ubiquitin-specific protease activity);GO:0043161(proteasome-mediated ubiquitin-dependent protein catabolic process);GO:0090266(regulation of mitotic cell cycle spindle assembly checkpoint);GO:1904667(negative regulation of ubiquitin protein ligase activity)","NA","NA","NA","ubiquitin specific peptidase 44 [Source:HGNC Symbol;Acc:HGNC:20064]",0,{"v":0.071661,"d":"0.07"},"-inf","-inf",1,1,"down","no"]
[142595,0,"chr3","-",170170732,170181747,"ENST00000481639",4,1075,"MSTRG.11333","PHC3","GO:0005634(nucleus);GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0007275(multicellular organism development);GO:0005654(nucleoplasm);GO:0031519(PcG protein complex);GO:0035102(PRC1 complex)","NA","NA","NA","polyhomeotic homolog 3 [Source:HGNC Symbol;Acc:HGNC:15682]",{"v":0.211244,"d":"0.21"},{"v":0.006928,"d":"0.01"},{"v":30.4913394919169,"d":"30.49"},{"v":4.93032762456917,"d":"4.93"},1,1,"up","no"]
[64788,0,"chr15","-",74902469,74906883,"ENST00000563877",4,742,"ENSG00000178761","FAM219B","NA","NA","NA","NA","family with sequence similarity 219 member B [Source:HGNC Symbol;Acc:HGNC:24695]",{"v":0.394492,"d":"0.39"},{"v":0.659806,"d":"0.66"},{"v":0.597890895202529,"d":"0.60"},{"v":-0.742045853459336,"d":"-0.74"},1,1,"down","no"]
[146958,0,"chr4","-",40542523,40629529,"ENST00000513044",2,2118,"MSTRG.11588","RBM47","GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0005634(nucleus);GO:0002244(hematopoietic progenitor cell differentiation);GO:0016554(cytidine to uridine editing)","NA","NA","NA","RNA binding motif protein 47 [Source:HGNC Symbol;Acc:HGNC:30358]",{"v":0.097497,"d":"0.10"},0,"inf","inf",1,1,"up","no"]
[178508,0,"chr7","+",128455849,128457924,"ENST00000435296",2,785,"ENSG00000135245","HILPDA","GO:0005615(extracellular space);GO:0008284(positive regulation of cell proliferation);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005654(nucleoplasm);GO:0005515(protein binding);GO:0005811(lipid particle);GO:0005576(extracellular region);GO:0005829(cytosol);GO:0034389(lipid particle organization);GO:0001819(positive regulation of cytokine production);GO:0009986(cell surface);GO:0005102(receptor binding);GO:0006950(response to stress);GO:0010884(positive regulation of lipid storage);GO:0030141(secretory granule);GO:0035425(autocrine signaling)","NA","NA","NA","hypoxia inducible lipid droplet associated [Source:HGNC Symbol;Acc:HGNC:28859]",{"v":0.003025,"d":"0.00"},{"v":0.010464,"d":"0.01"},{"v":0.289086391437309,"d":"0.29"},{"v":-1.79042739844876,"d":"-1.79"},1,1,"down","no"]
[11058,0,"chr1","+",152719522,152720470,"ENST00000368775",1,949,"ENSG00000198854","C1orf68","GO:0005737(cytoplasm);GO:0003674(molecular_function);GO:0070062(extracellular exosome);GO:0005198(structural molecule activity);GO:0008544(epidermis development);GO:0018149(peptide cross-linking);GO:0030216(keratinocyte differentiation);GO:0001533(cornified envelope)","NA","NA","NA","chromosome 1 open reading frame 68 [Source:HGNC Symbol;Acc:HGNC:29468]",0,0,1,0,1,1,"no","no"]
[24893,0,"chr11","-",644233,687936,"ENST00000527170",10,1623,"ENSG00000177030","DEAF1","GO:0003677(DNA binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0001650(fibrillar center);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0007275(multicellular organism development);GO:0007399(nervous system development);GO:0045893(positive regulation of transcription, DNA-templated);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0045892(negative regulation of transcription, DNA-templated);GO:0006366(transcription from RNA polymerase II promoter);GO:0009653(anatomical structure morphogenesis);GO:0000977(RNA polymerase II regulatory region sequence-specific DNA binding);GO:0001227(transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding);GO:0001843(neural tube closure);GO:0001662(behavioral fear response);GO:0007281(germ cell development);GO:0008542(visual learning);GO:0033599(regulation of mammary gland epithelial cell proliferation);GO:0048706(embryonic skeletal system development);GO:0005667(transcription factor complex)","NA","NA","NA","DEAF1, transcription factor [Source:HGNC Symbol;Acc:HGNC:14677]",0,{"v":0.03343,"d":"0.03"},"-inf","-inf",1,1,"down","no"]
[60601,0,"chr15","-",32451165,32454902,"ENST00000562377",7,555,"ENSG00000206127","GOLGA8O","GO:0005515(protein binding);GO:0005794(Golgi apparatus)","NA","NA","NA","golgin A8 family member O [Source:HGNC Symbol;Acc:HGNC:44406]",{"v":0.01743,"d":"0.02"},{"v":0.397502,"d":"0.40"},{"v":0.0438488359806995,"d":"0.04"},{"v":-4.51131764464547,"d":"-4.51"},1,1,"down","no"]
[34199,0,"chr11","-",93730194,93741493,"ENST00000526015",14,1735,"MSTRG.2810","TAF1D","GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0005668(RNA polymerase transcription factor SL1 complex);GO:0005815(microtubule organizing center);GO:0045815(positive regulation of gene expression, epigenetic);GO:0006361(transcription initiation from RNA polymerase I promoter);GO:0006362(transcription elongation from RNA polymerase I promoter);GO:0006363(termination of RNA polymerase I transcription)","NA","NA","NA","TATA-box binding protein associated factor, RNA polymerase I subunit D [Source:HGNC Symbol;Acc:HGNC:28759]",{"v":1.524826,"d":"1.52"},{"v":0.023409,"d":"0.02"},{"v":65.1384510231108,"d":"65.14"},{"v":6.02543750808377,"d":"6.03"},1,1,"up","no"]
[105812,0,"chr19","-",55226748,55229264,"ENST00000327042",3,1637,"MSTRG.8436","TMEM86B","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016787(hydrolase activity);GO:0005515(protein binding);GO:0005789(endoplasmic reticulum membrane);GO:0036151(phosphatidylcholine acyl-chain remodeling);GO:0046485(ether lipid metabolic process);GO:0016803(ether hydrolase activity);GO:0047408(alkenylglycerophosphocholine hydrolase activity);GO:0047409(alkenylglycerophosphoethanolamine hydrolase activity)","00565(Ether lipid metabolism)","K18575","EC:3.3.2.2","transmembrane protein 86B [Source:HGNC Symbol;Acc:HGNC:28448]",0,{"v":0.034652,"d":"0.03"},"-inf","-inf",1,1,"down","no"]
[33452,0,"chr11","-",77616250,77622531,"ENST00000526009",4,747,"MSTRG.2732","CLNS1A","GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0005886(plasma membrane);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0006821(chloride transport);GO:0000387(spliceosomal snRNP assembly);GO:0006884(cell volume homeostasis);GO:0034709(methylosome);GO:0034715(pICln-Sm protein complex);GO:0046982(protein heterodimerization activity)","03013(RNA transport)","NA","NA","chloride nucleotide-sensitive channel 1A [Source:HGNC Symbol;Acc:HGNC:2080]",{"v":0.037463,"d":"0.04"},0,"inf","inf",1,1,"up","no"]
[118890,0,"chr2","-",216487804,216498750,"ENST00000431856",2,584,"MSTRG.9407","AC098820.1","NA","NA","NA","NA","NA",{"v":0.158594,"d":"0.16"},{"v":0.086855,"d":"0.09"},{"v":1.82596281158252,"d":"1.83"},{"v":0.868657383015555,"d":"0.87"},1,1,"up","no"]
[131466,0,"chr22","-",39315369,39319595,"ENST00000427905",5,782,"MSTRG.10475","RPL3","GO:0005730(nucleolus);GO:0005829(cytosol);GO:0030529(intracellular ribonucleoprotein complex);GO:0005622(intracellular);GO:0003735(structural constituent of ribosome);GO:0006412(translation);GO:0005840(ribosome);GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005925(focal adhesion);GO:0000027(ribosomal large subunit assembly);GO:0005515(protein binding);GO:0070062(extracellular exosome);GO:0043234(protein complex);GO:0006413(translational initiation);GO:0006364(rRNA processing);GO:0000184(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay);GO:0019083(viral transcription);GO:0006614(SRP-dependent cotranslational protein targeting to membrane);GO:0022625(cytosolic large ribosomal subunit);GO:0008097(5S rRNA binding);GO:0071353(cellular response to interleukin-4)","03010(Ribosome)","NA","NA","ribosomal protein L3 [Source:HGNC Symbol;Acc:HGNC:10332]",{"v":3.396883,"d":"3.40"},{"v":2.945132,"d":"2.95"},{"v":1.15338905013426,"d":"1.15"},{"v":0.205879231138679,"d":"0.21"},1,1,"up","no"]
[94253,0,"chr19","+",1273504,1274810,"ENST00000586555",2,716,"MSTRG.7603","CIRBP","GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005730(nucleolus);GO:0005515(protein binding);GO:0005654(nucleoplasm);GO:0045727(positive regulation of translation);GO:0010494(cytoplasmic stress granule);GO:0009411(response to UV);GO:0003730(mRNA 3'-UTR binding);GO:0034063(stress granule assembly);GO:0030371(translation repressor activity);GO:0048255(mRNA stabilization);GO:0009409(response to cold);GO:0070181(small ribosomal subunit rRNA binding);GO:0017148(negative regulation of translation)","NA","NA","NA","cold inducible RNA binding protein [Source:HGNC Symbol;Acc:HGNC:1982]",{"v":0.274403,"d":"0.27"},{"v":0.014233,"d":"0.01"},{"v":19.2793508044685,"d":"19.28"},{"v":4.26898456725697,"d":"4.27"},1,1,"up","no"]
[120390,0,"chr2","+",233386054,233388985,"ENST00000489613",2,890,"MSTRG.9505","DGKD","GO:0005634(nucleus);GO:0006810(transport);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0015031(protein transport);GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0005829(cytosol);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0035556(intracellular signal transduction);GO:0008152(metabolic process);GO:0003951(NAD+ kinase activity);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0007165(signal transduction);GO:0007275(multicellular organism development);GO:0004143(diacylglycerol kinase activity);GO:0007205(protein kinase C-activating G-protein coupled receptor signaling pathway);GO:0006897(endocytosis);GO:0030168(platelet activation);GO:0010033(response to organic substance);GO:0007173(epidermal growth factor receptor signaling pathway);GO:0042803(protein homodimerization activity);GO:0046982(protein heterodimerization activity);GO:0016049(cell growth);GO:0051260(protein homooligomerization);GO:0046834(lipid phosphorylation);GO:0019992(diacylglycerol binding);GO:0019932(second-messenger-mediated signaling);GO:0046339(diacylglycerol metabolic process);GO:0005622(intracellular)","00561(Glycerolipid metabolism);00564(Glycerophospholipid metabolism);04070(Phosphatidylinositol signaling system);04072(Phospholipase D signaling pathway);05231(Choline metabolism in cancer)","NA","NA","diacylglycerol kinase delta [Source:HGNC Symbol;Acc:HGNC:2851]",{"v":0.043958,"d":"0.04"},{"v":0.019899,"d":"0.02"},{"v":2.20905573144379,"d":"2.21"},{"v":1.14342981636785,"d":"1.14"},1,1,"up","no"]
[170290,0,"chr6","-",152987362,153002685,"ENST00000367230",6,3431,"ENSG00000112031","MTRF1L","GO:0003747(translation release factor activity);GO:0006415(translational termination);GO:0006412(translation);GO:0005739(mitochondrion);GO:0005759(mitochondrial matrix);GO:0070126(mitochondrial translational termination)","NA","NA","NA","mitochondrial translational release factor 1 like [Source:HGNC Symbol;Acc:HGNC:21051]",{"v":0.091714,"d":"0.09"},0,"inf","inf",1,1,"up","no"]
[105327,0,"chr19","-",54048366,54063953,"ENST00000425006",5,608,"MSTRG.8398","VSTM1","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005576(extracellular region);GO:0005125(cytokine activity);GO:0005615(extracellular space);GO:0002376(immune system process)","NA","NA","NA","V-set and transmembrane domain containing 1 [Source:HGNC Symbol;Acc:HGNC:29455]",{"v":0.501393,"d":"0.50"},0,"inf","inf",1,1,"up","no"]
[146687,0,"chr4","+",37977310,38090065,"ENST00000446803",12,1987,"MSTRG.11569","TBC1D1","GO:0005634(nucleus);GO:0005096(GTPase activator activity);GO:0017137(Rab GTPase binding);GO:0006886(intracellular protein transport);GO:0031338(regulation of vesicle fusion);GO:0090630(activation of GTPase activity);GO:0005622(intracellular);GO:0012505(endomembrane system);GO:0005515(protein binding);GO:0005829(cytosol);GO:0061024(membrane organization);GO:0032880(regulation of protein localization)","04152(AMPK signaling pathway)","NA","NA","TBC1 domain family member 1 [Source:HGNC Symbol;Acc:HGNC:11578]",{"v":1.346704,"d":"1.35"},{"v":0.295271,"d":"0.30"},{"v":4.56090845359009,"d":"4.56"},{"v":2.18932121275715,"d":"2.19"},1,1,"up","no"]
[6612,0,"chr1","+",59297094,59791606,"ENST00000634364",20,5360,"ENSG00000172456","FGGY","GO:0016773(phosphotransferase activity, alcohol group as acceptor);GO:0005975(carbohydrate metabolic process);GO:0005623(cell);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0046835(carbohydrate phosphorylation);GO:0003674(molecular_function);GO:0005575(cellular_component);GO:0070050(neuron cellular homeostasis);GO:0019150(D-ribulokinase activity);GO:0019321(pentose metabolic process)","NA","NA","NA","FGGY carbohydrate kinase domain containing [Source:HGNC Symbol;Acc:HGNC:25610]",{"v":0.007944,"d":"0.01"},{"v":9.495E-3,"d":"0.01"},{"v":0.836650868878357,"d":"0.84"},{"v":-0.257302377508486,"d":"-0.26"},1,1,"down","no"]
[64369,0,"chr15","+",72686179,72738475,"ENST00000395205",15,2450,"ENSG00000140463","BBS4","GO:0006810(transport);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0015031(protein transport);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0005856(cytoskeleton);GO:0042995(cell projection);GO:0005515(protein binding);GO:0050896(response to stimulus);GO:0005813(centrosome);GO:0005815(microtubule organizing center);GO:0034464(BBSome);GO:0005634(nucleus);GO:1905515(non-motile cilium assembly);GO:0000226(microtubule cytoskeleton organization);GO:0001764(neuron migration);GO:0001843(neural tube closure);GO:0001895(retina homeostasis);GO:0003085(negative regulation of systemic arterial blood pressure);GO:0007286(spermatid development);GO:0007608(sensory perception of smell);GO:0008104(protein localization);GO:0010629(negative regulation of gene expression);GO:0016358(dendrite development);GO:0019216(regulation of lipid metabolic process);GO:0021591(ventricular system development);GO:0021756(striatum development);GO:0021766(hippocampus development);GO:0021987(cerebral cortex development);GO:0030534(adult behavior);GO:0030837(negative regulation of actin filament polymerization);GO:0033210(leptin-mediated signaling pathway);GO:0033365(protein localization to organelle);GO:0034260(negative regulation of GTPase activity);GO:0035176(social behavior);GO:0035845(photoreceptor cell outer segment organization);GO:0038108(negative regulation of appetite by leptin-mediated signaling pathway);GO:0040018(positive regulation of multicellular organism growth);GO:0044321(response to leptin);GO:0045444(fat cell differentiation);GO:0045494(photoreceptor cell maintenance);GO:0045724(positive regulation of cilium assembly);GO:0046548(retinal rod cell development);GO:0048854(brain morphogenesis);GO:0051492(regulation of stress fiber assembly);GO:0060271(cilium assembly);GO:0060296(regulation of cilium beat frequency involved in ciliary motility);GO:0060324(face development);GO:0060613(fat pad development);GO:0071539(protein localization to centrosome);GO:1902855(regulation of non-motile cilium assembly);GO:1903546(protein localization to photoreceptor outer segment);GO:0001750(photoreceptor outer segment);GO:0001917(photoreceptor inner segment);GO:0031514(motile cilium);GO:0032391(photoreceptor connecting cilium);GO:0034451(centriolar satellite);GO:0005929(cilium);GO:0030030(cell projection organization);GO:0007601(visual perception);GO:0060170(ciliary membrane);GO:0007098(centrosome cycle);GO:0035869(ciliary transition zone);GO:0001947(heart looping);GO:0003777(microtubule motor activity);GO:0000242(pericentriolar material);GO:0097730(non-motile cilium);GO:0034452(dynactin binding);GO:0043014(alpha-tubulin binding);GO:0000281(mitotic cytokinesis);GO:0061512(protein localization to cilium);GO:0034454(microtubule anchoring at centrosome);GO:0005814(centriole);GO:0036064(ciliary basal body);GO:0001103(RNA polymerase II repressing transcription factor binding);GO:0032402(melanosome transport);GO:0050893(sensory processing);GO:0048487(beta-tubulin binding);GO:0032465(regulation of cytokinesis);GO:0046907(intracellular transport);GO:0051457(maintenance of protein location in nucleus);GO:0016021(integral component of membrane)","NA","NA","NA","Bardet-Biedl syndrome 4 [Source:HGNC Symbol;Acc:HGNC:969]",{"v":0.011856,"d":"0.01"},0,"inf","inf",1,1,"up","no"]
[94866,0,"chr19","+",3572977,3575614,"ENST00000453933",4,759,"MSTRG.7668","HMG20B","GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0003677(DNA binding);GO:0016604(nuclear body);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0016569(covalent chromatin modification);GO:0016575(histone deacetylation);GO:0005694(chromosome);GO:0005515(protein binding);GO:0007049(cell cycle);GO:0004407(histone deacetylase activity);GO:0007596(blood coagulation);GO:0046982(protein heterodimerization activity);GO:0033234(negative regulation of protein sumoylation);GO:0035914(skeletal muscle cell differentiation);GO:0045666(positive regulation of neuron differentiation)","NA","NA","NA","high mobility group 20B [Source:HGNC Symbol;Acc:HGNC:5002]",{"v":0.533331,"d":"0.53"},0,"inf","inf",1,1,"up","no"]
[149158,0,"chr4","+",87441871,87454456,"ENST00000515371",5,576,"ENSG00000170502","NUDT9","GO:0016787(hydrolase activity);GO:0005739(mitochondrion);GO:0031965(nuclear membrane);GO:0030054(cell junction);GO:0043262(adenosine-diphosphatase activity);GO:0046032(ADP catabolic process);GO:0046709(IDP catabolic process);GO:0070062(extracellular exosome);GO:0005622(intracellular);GO:0005759(mitochondrial matrix);GO:0034656(nucleobase-containing small molecule catabolic process);GO:0047631(ADP-ribose diphosphatase activity);GO:0019144(ADP-sugar diphosphatase activity)","00230(Purine metabolism)","NA","NA","nudix hydrolase 9 [Source:HGNC Symbol;Acc:HGNC:8056]",{"v":0.398009,"d":"0.40"},{"v":0.115648,"d":"0.12"},{"v":3.44155540951854,"d":"3.44"},{"v":1.78306073772949,"d":"1.78"},1,1,"up","no"]
[84493,0,"chr17","-",45439514,45440373,"ENST00000585506",2,332,"MSTRG.6928","PLEKHM1","GO:0006810(transport);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0015031(protein transport);GO:0043231(intracellular membrane-bounded organelle);GO:0046872(metal ion binding);GO:0005730(nucleolus);GO:0035556(intracellular signal transduction);GO:0005765(lysosomal membrane);GO:0006914(autophagy);GO:0005764(lysosome);GO:0005768(endosome);GO:0010008(endosome membrane);GO:0005622(intracellular)","NA","NA","NA","pleckstrin homology and RUN domain containing M1 [Source:HGNC Symbol;Acc:HGNC:29017]",{"v":0.647341,"d":"0.65"},{"v":0.166785,"d":"0.17"},{"v":3.88129028389843,"d":"3.88"},{"v":1.95653633713767,"d":"1.96"},1,1,"up","no"]
[155170,0,"chr5","+",62311813,62385719,"ENST00000506857",20,2219,"MSTRG.12079","KIF2A","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0005634(nucleus);GO:0005730(nucleolus);GO:0051301(cell division);GO:0005813(centrosome);GO:0003777(microtubule motor activity);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0007049(cell cycle);GO:0016604(nuclear body);GO:0008017(microtubule binding);GO:0007275(multicellular organism development);GO:0007399(nervous system development);GO:0030154(cell differentiation);GO:0005874(microtubule);GO:0007018(microtubule-based movement);GO:0000922(spindle pole);GO:0005815(microtubule organizing center);GO:0005819(spindle);GO:0005829(cytosol);GO:0006890(retrograde vesicle-mediated transport, Golgi to ER);GO:0016887(ATPase activity);GO:0005876(spindle microtubule);GO:0003774(motor activity);GO:0007052(mitotic spindle organization);GO:0007062(sister chromatid cohesion);GO:0019886(antigen processing and presentation of exogenous peptide antigen via MHC class II);GO:0090307(mitotic spindle assembly);GO:0005871(kinesin complex);GO:0097228(sperm principal piece)","NA","NA","NA","kinesin family member 2A [Source:HGNC Symbol;Acc:HGNC:6318]",{"v":2.4e-05,"d":"0.00"},{"v":0.000623,"d":"0.00"},{"v":0.0385232744783307,"d":"0.04"},{"v":-4.69812585230285,"d":"-4.70"},1,1,"down","no"]
[96206,0,"chr19","-",9787408,9793180,"ENST00000589038",2,650,"ENSG00000196605","ZNF846","GO:0003676(nucleic acid binding);GO:0006355(regulation of transcription, DNA-templated);GO:0005622(intracellular);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0005515(protein binding)","NA","NA","NA","zinc finger protein 846 [Source:HGNC Symbol;Acc:HGNC:27260]",{"v":0.076108,"d":"0.08"},{"v":0.449549,"d":"0.45"},{"v":0.169298563671591,"d":"0.17"},{"v":-2.56235836142146,"d":"-2.56"},1,1,"down","no"]
[193318,0,"chr9","-",124971258,124976186,"ENST00000494102",4,562,"ENSG00000173611","SCAI","GO:0006351(transcription, DNA-templated);GO:0003714(transcription corepressor activity);GO:1903507(negative regulation of nucleic acid-templated transcription);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0006355(regulation of transcription, DNA-templated);GO:0031965(nuclear membrane);GO:0005515(protein binding);GO:0005654(nucleoplasm);GO:0009968(negative regulation of signal transduction);GO:0030336(negative regulation of cell migration);GO:0035024(negative regulation of Rho protein signal transduction)","NA","NA","NA","suppressor of cancer cell invasion [Source:HGNC Symbol;Acc:HGNC:26709]",0,0,1,0,1,1,"no","no"]
[143859,0,"chr3","+",186783577,186786216,"ENST00000495049",4,576,"MSTRG.11403","EIF4A2","GO:0003676(nucleic acid binding);GO:0005524(ATP binding);GO:0003723(RNA binding);GO:0003743(translation initiation factor activity);GO:0006412(translation);GO:0006413(translational initiation);GO:0000166(nucleotide binding);GO:0016787(hydrolase activity);GO:0004386(helicase activity);GO:0005515(protein binding);GO:0048471(perinuclear region of cytoplasm);GO:0005730(nucleolus);GO:0005829(cytosol);GO:0004004(ATP-dependent RNA helicase activity);GO:0010501(RNA secondary structure unwinding);GO:0000289(nuclear-transcribed mRNA poly(A) tail shortening);GO:0016032(viral process);GO:0016887(ATPase activity);GO:0006446(regulation of translational initiation);GO:0016281(eukaryotic translation initiation factor 4F complex);GO:1900260(negative regulation of RNA-directed 5'-3' RNA polymerase activity);GO:1990830(cellular response to leukemia inhibitory factor)","03013(RNA transport)","NA","NA","eukaryotic translation initiation factor 4A2 [Source:HGNC Symbol;Acc:HGNC:3284]",{"v":0.189431,"d":"0.19"},{"v":0.075622,"d":"0.08"},{"v":2.5049720980667,"d":"2.50"},{"v":1.32479453387757,"d":"1.32"},1,1,"up","no"]
[92768,0,"chr18","-",56597208,56638645,"ENST00000217515",8,6894,"ENSG00000091164","TXNL1","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0055114(oxidation-reduction process);GO:0045454(cell redox homeostasis);GO:0000502(proteasome complex);GO:0098869(cellular oxidant detoxification);GO:0070062(extracellular exosome);GO:0004791(thioredoxin-disulfide reductase activity);GO:0015035(protein disulfide oxidoreductase activity);GO:0015036(disulfide oxidoreductase activity);GO:0016671(oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor);GO:0047134(protein-disulfide reductase activity);GO:0034599(cellular response to oxidative stress);GO:0005623(cell);GO:0006662(glycerol ether metabolic process)","NA","NA","NA","thioredoxin like 1 [Source:HGNC Symbol;Acc:HGNC:12436]",0,{"v":5.576161,"d":"5.58"},"-inf","-inf",1,1,"down","no"]
[30002,0,"chr11","+",61488842,61490931,"ENST00000366212",4,488,"MSTRG.2446","PPP1R32","GO:0005515(protein binding);GO:0019902(phosphatase binding)","NA","NA","NA","protein phosphatase 1 regulatory subunit 32 [Source:HGNC Symbol;Acc:HGNC:28869]",0,{"v":0.041784,"d":"0.04"},"-inf","-inf",1,1,"down","no"]
[35940,0,"chr11","-",119055155,119057112,"ENST00000622474",5,549,"MSTRG.2928","HYOU1","GO:0016020(membrane);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0005783(endoplasmic reticulum);GO:0005925(focal adhesion);GO:0006898(receptor-mediated endocytosis);GO:0005576(extracellular region);GO:0005788(endoplasmic reticulum lumen);GO:0070062(extracellular exosome);GO:0036498(IRE1-mediated unfolded protein response);GO:0034976(response to endoplasmic reticulum stress);GO:0051087(chaperone binding);GO:0071682(endocytic vesicle lumen);GO:0005790(smooth endoplasmic reticulum);GO:0071456(cellular response to hypoxia);GO:1903298(negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway);GO:0006888(ER to Golgi vesicle-mediated transport);GO:0002931(response to ischemia);GO:0043066(negative regulation of apoptotic process);GO:1903382(negative regulation of endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway);GO:0034663(endoplasmic reticulum chaperone complex)","04141(Protein processing in endoplasmic reticulum)","NA","NA","hypoxia up-regulated 1 [Source:HGNC Symbol;Acc:HGNC:16931]",0,0,1,0,1,1,"no","no"]
[24474,0,"chr10","-",132808392,132942585,"ENST00000368586",58,8278,"ENSG00000171811","CFAP46","GO:0005737(cytoplasm);GO:0005856(cytoskeleton);GO:0042995(cell projection);GO:0005929(cilium);GO:0030030(cell projection organization);GO:0005930(axoneme);GO:0060294(cilium movement involved in cell motility);GO:0035082(axoneme assembly)","NA","NA","NA","cilia and flagella associated protein 46 [Source:HGNC Symbol;Acc:HGNC:25247]",0,0,1,0,1,1,"no","no"]
[199032,0,"chrX","+",103215124,103217099,"ENST00000372691",2,1066,"MSTRG.15392","BEX4","GO:0005634(nucleus);GO:0005737(cytoplasm)","NA","NA","NA","brain expressed X-linked 4 [Source:HGNC Symbol;Acc:HGNC:25475]",0,0,1,0,1,1,"no","no"]
[75107,0,"chr16","-",69976352,70065853,"ENST00000530079",25,2764,"ENSG00000196696","PDXDC2P-NPIPB14P","NA","NA","NA","NA","nuclear pore complex-interacting protein [Source:NCBI gene;Acc:283970]",{"v":0.207127,"d":"0.21"},{"v":0.318137,"d":"0.32"},{"v":0.651062278200901,"d":"0.65"},{"v":-0.619132542043036,"d":"-0.62"},1,1,"down","no"]
[131513,0,"chr22","-",39529156,39532761,"ENST00000420879",5,861,"MSTRG.10479","RPS19BP1","GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005730(nucleolus);GO:0005829(cytosol);GO:0005840(ribosome);GO:0005515(protein binding);GO:0005654(nucleoplasm);GO:0019899(enzyme binding)","NA","NA","NA","ribosomal protein S19 binding protein 1 [Source:HGNC Symbol;Acc:HGNC:28749]",{"v":0.228853,"d":"0.23"},{"v":0.513064,"d":"0.51"},{"v":0.446051564717072,"d":"0.45"},{"v":-1.16471759581471,"d":"-1.16"},1,1,"down","no"]
[30629,0,"chr11","+",64200252,64204143,"ENST00000540887",4,877,"MSTRG.2500","STIP1","GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005515(protein binding);GO:0005829(cytosol);GO:0043234(protein complex);GO:0006950(response to stress);GO:0005794(Golgi apparatus);GO:0008022(protein C-terminus binding);GO:0030544(Hsp70 protein binding);GO:0051087(chaperone binding);GO:0043209(myelin sheath)","05020(Prion diseases)","NA","NA","stress induced phosphoprotein 1 [Source:HGNC Symbol;Acc:HGNC:11387]",{"v":0.606706,"d":"0.61"},{"v":0.496259,"d":"0.50"},{"v":1.22255918784344,"d":"1.22"},{"v":0.289904312164167,"d":"0.29"},1,1,"up","no"]
[48192,0,"chr12","-",124334344,124335181,"ENST00000474079",2,321,"ENSG00000196498","NCOR2","GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0003677(DNA binding);GO:0001012(RNA polymerase II regulatory region DNA binding);GO:0003682(chromatin binding);GO:0016922(ligand-dependent nuclear receptor binding);GO:0032403(protein complex binding);GO:0035259(glucocorticoid receptor binding);GO:0042974(retinoic acid receptor binding);GO:0046965(retinoid X receptor binding);GO:0007595(lactation);GO:0010243(response to organonitrogen compound);GO:0032355(response to estradiol);GO:0044849(estrous cycle);GO:0000785(chromatin);GO:0016020(membrane);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0005515(protein binding);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0003714(transcription corepressor activity);GO:0008134(transcription factor binding);GO:0047485(protein N-terminus binding);GO:0000790(nuclear chromatin);GO:0016363(nuclear matrix);GO:0005112(Notch binding);GO:0042826(histone deacetylase binding);GO:0019216(regulation of lipid metabolic process);GO:0017053(transcriptional repressor complex);GO:1903799(negative regulation of production of miRNAs involved in gene silencing by miRNA);GO:0000118(histone deacetylase complex);GO:0072365(regulation of cellular ketone metabolic process by negative regulation of transcription from RNA polymerase II promoter);GO:0016604(nuclear body)","04330(Notch signaling pathway);05169(Epstein-Barr virus infection)","NA","NA","nuclear receptor corepressor 2 [Source:HGNC Symbol;Acc:HGNC:7673]",{"v":0.012055,"d":"0.01"},{"v":0.035581,"d":"0.04"},{"v":0.338804418088306,"d":"0.34"},{"v":-1.56147540701616,"d":"-1.56"},1,1,"down","no"]
[128722,0,"chr22","+",20124139,20127181,"ENST00000486575",2,2177,"MSTRG.10150","RANBP1","GO:0005829(cytosol);GO:0046907(intracellular transport);GO:0005737(cytoplasm);GO:0005634(nucleus);GO:0050790(regulation of catalytic activity);GO:0043547(positive regulation of GTPase activity);GO:0007165(signal transduction);GO:0005096(GTPase activator activity);GO:0005813(centrosome);GO:0045296(cadherin binding);GO:0007051(spindle organization);GO:0005515(protein binding);GO:0008536(Ran GTPase binding);GO:0016032(viral process);GO:0006606(protein import into nucleus);GO:0006511(ubiquitin-dependent protein catabolic process);GO:0006405(RNA export from nucleus);GO:0005635(nuclear envelope);GO:0000082(G1/S transition of mitotic cell cycle);GO:0005092(GDP-dissociation inhibitor activity);GO:0046604(positive regulation of mitotic centrosome separation);GO:0005622(intracellular);GO:0010976(positive regulation of neuron projection development);GO:0035690(cellular response to drug);GO:0051592(response to calcium ion);GO:0072750(cellular response to leptomycin B);GO:0032838(cell projection cytoplasm);GO:1904115(axon cytoplasm)","05203(Viral carcinogenesis);05166(HTLV-I infection)","NA","NA","RAN binding protein 1 [Source:HGNC Symbol;Acc:HGNC:9847]",{"v":0.128416,"d":"0.13"},{"v":0.050375,"d":"0.05"},{"v":2.54920099255583,"d":"2.55"},{"v":1.35004512758994,"d":"1.35"},1,1,"up","no"]
[106903,0,"chr2","+",3379720,3389000,"ENST00000482645",2,1538,"MSTRG.8492","TRAPPC12","GO:0006810(transport);GO:0005634(nucleus);GO:0043547(positive regulation of GTPase activity);GO:0006508(proteolysis);GO:0048471(perinuclear region of cytoplasm);GO:0016192(vesicle-mediated transport);GO:0000776(kinetochore);GO:0004175(endopeptidase activity);GO:0005515(protein binding);GO:0005829(cytosol);GO:0017112(Rab guanyl-nucleotide exchange factor activity);GO:0061024(membrane organization);GO:0006888(ER to Golgi vesicle-mediated transport);GO:0051259(protein oligomerization);GO:0051310(metaphase plate congression);GO:0007030(Golgi organization);GO:0005793(endoplasmic reticulum-Golgi intermediate compartment);GO:0030008(TRAPP complex);GO:0090234(regulation of kinetochore assembly);GO:1905342(positive regulation of protein localization to kinetochore)","NA","NA","NA","trafficking protein particle complex 12 [Source:HGNC Symbol;Acc:HGNC:24284]",{"v":0.220029,"d":"0.22"},{"v":0.333358,"d":"0.33"},{"v":0.660038157176369,"d":"0.66"},{"v":-0.599378664995242,"d":"-0.60"},1,1,"down","no"]
[32251,0,"chr11","+",68460755,68614575,"ENST00000524904",24,4292,"MSTRG.2632","PPP6R3","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0000139(Golgi membrane);GO:0048208(COPII vesicle coating);GO:0019903(protein phosphatase binding);GO:0043666(regulation of phosphoprotein phosphatase activity);GO:0006516(glycoprotein catabolic process)","NA","NA","NA","protein phosphatase 6 regulatory subunit 3 [Source:HGNC Symbol;Acc:HGNC:1173]",{"v":2.28421,"d":"2.28"},0,"inf","inf",1,1,"up","no"]
[86372,0,"chr17","-",60083566,60088256,"ENST00000588180",4,605,"ENSG00000261040","WFDC21P","NA","NA","NA","NA","WAP four-disulfide core domain 21, pseudogene [Source:HGNC Symbol;Acc:HGNC:50357]",{"v":0.04172,"d":"0.04"},{"v":0.10863,"d":"0.11"},{"v":0.384055969805763,"d":"0.38"},{"v":-1.38061151967757,"d":"-1.38"},1,1,"down","no"]
[176373,0,"chr7","-",97864259,97871879,"ENST00000437657",4,745,"ENSG00000070669","ASNS","GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0005829(cytosol);GO:0016874(ligase activity);GO:0005515(protein binding);GO:0008652(cellular amino acid biosynthetic process);GO:0006541(glutamine metabolic process);GO:0004066(asparagine synthase (glutamine-hydrolyzing) activity);GO:0006529(asparagine biosynthetic process);GO:0043066(negative regulation of apoptotic process);GO:0042803(protein homodimerization activity);GO:0042149(cellular response to glucose starvation);GO:0045931(positive regulation of mitotic cell cycle);GO:0036499(PERK-mediated unfolded protein response);GO:0070981(L-asparagine biosynthetic process);GO:0048037(cofactor binding);GO:0001889(liver development);GO:0006520(cellular amino acid metabolic process);GO:0009416(response to light stimulus);GO:0009612(response to mechanical stimulus);GO:0009636(response to toxic substance);GO:0031427(response to methotrexate);GO:0031667(response to nutrient levels);GO:0032354(response to follicle-stimulating hormone);GO:0032870(cellular response to hormone stimulus);GO:0043200(response to amino acid)","00250(Alanine, aspartate and glutamate metabolism)","NA","NA","asparagine synthetase (glutamine-hydrolyzing) [Source:HGNC Symbol;Acc:HGNC:753]",{"v":0.015053,"d":"0.02"},0,"inf","inf",1,1,"up","no"]
[183178,0,"chr8","+",38846469,38848282,"ENST00000522548",2,679,"MSTRG.14302","TACC1","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0051301(cell division);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0007049(cell cycle);GO:0005815(microtubule organizing center);GO:0030496(midbody);GO:0000226(microtubule cytoskeleton organization);GO:0008283(cell proliferation);GO:0021987(cerebral cortex development);GO:0015630(microtubule cytoskeleton)","NA","NA","NA","transforming acidic coiled-coil containing protein 1 [Source:HGNC Symbol;Acc:HGNC:11522]",{"v":0.211426,"d":"0.21"},{"v":0.034003,"d":"0.03"},{"v":6.21786312972385,"d":"6.22"},{"v":2.63641885980507,"d":"2.64"},1,1,"up","no"]
[173720,"j","chr7","+",44618835,44708813,"MSTRG.13632.9",23,4125,"MSTRG.13632","OGDH","NA","NA","NA","NA","NA",{"v":0.005885,"d":"0.01"},{"v":0.011076,"d":"0.01"},{"v":0.531328999638859,"d":"0.53"},{"v":-0.912322638441124,"d":"-0.91"},1,1,"down","no"]
[176315,0,"chr7","-",96645391,96709780,"ENST00000623693",3,729,"MSTRG.13780","SEM1","GO:0006406(mRNA export from nucleus);GO:0043248(proteasome assembly);GO:0008541(proteasome regulatory particle, lid subcomplex);GO:0005515(protein binding);GO:0000502(proteasome complex);GO:0038095(Fc-epsilon receptor signaling pathway);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0000165(MAPK cascade);GO:0000209(protein polyubiquitination);GO:0002223(stimulatory C-type lectin receptor signaling pathway);GO:0002479(antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent);GO:0006521(regulation of cellular amino acid metabolic process);GO:0010972(negative regulation of G2/M transition of mitotic cell cycle);GO:0016579(protein deubiquitination);GO:0031145(anaphase-promoting complex-dependent catabolic process);GO:0031146(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process);GO:0033209(tumor necrosis factor-mediated signaling pathway);GO:0038061(NIK/NF-kappaB signaling);GO:0043161(proteasome-mediated ubiquitin-dependent protein catabolic process);GO:0043488(regulation of mRNA stability);GO:0043687(post-translational protein modification);GO:0050852(T cell receptor signaling pathway);GO:0051437(positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition);GO:0055085(transmembrane transport);GO:0060071(Wnt signaling pathway, planar cell polarity pathway);GO:0061418(regulation of transcription from RNA polymerase II promoter in response to hypoxia);GO:0090090(negative regulation of canonical Wnt signaling pathway);GO:0090263(positive regulation of canonical Wnt signaling pathway);GO:1902036(regulation of hematopoietic stem cell differentiation);GO:0051436(negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle);GO:0032039(integrator complex)","03050(Proteasome);03440(Homologous recombination);05169(Epstein-Barr virus infection)","NA","NA","SEM1, 26S proteasome complex subunit [Source:HGNC Symbol;Acc:HGNC:10845]",0,0,1,0,1,1,"no","no"]
[34877,0,"chr11","-",108473075,108491217,"ENST00000530529",8,3241,"ENSG00000178202","KDELC2","GO:0005783(endoplasmic reticulum);GO:0005788(endoplasmic reticulum lumen);GO:0003674(molecular_function);GO:0008150(biological_process);GO:0005575(cellular_component);GO:0046527(glucosyltransferase activity);GO:0006664(glycolipid metabolic process)","NA","NA","NA","KDEL motif containing 2 [Source:HGNC Symbol;Acc:HGNC:28496]",0,0,1,0,1,1,"no","no"]
[131323,0,"chr22","+",38656676,38671136,"ENST00000492576",4,584,"MSTRG.10454","CBY1","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016607(nuclear speck);GO:0005794(Golgi apparatus);GO:0005856(cytoskeleton);GO:0042995(cell projection);GO:0005515(protein binding);GO:0030154(cell differentiation);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0045444(fat cell differentiation);GO:0030030(cell projection organization);GO:0005814(centriole);GO:0005802(trans-Golgi network);GO:0030178(negative regulation of Wnt signaling pathway);GO:0042802(identical protein binding);GO:0045892(negative regulation of transcription, DNA-templated);GO:0008013(beta-catenin binding);GO:0042803(protein homodimerization activity);GO:0008104(protein localization);GO:0051289(protein homotetramerization);GO:0055007(cardiac muscle cell differentiation);GO:0060271(cilium assembly);GO:0090090(negative regulation of canonical Wnt signaling pathway);GO:0036064(ciliary basal body)","NA","NA","NA","chibby family member 1, beta catenin antagonist [Source:HGNC Symbol;Acc:HGNC:1307]",{"v":0.066307,"d":"0.07"},{"v":0.293766,"d":"0.29"},{"v":0.225713663255789,"d":"0.23"},{"v":-2.14743434222053,"d":"-2.15"},1,1,"down","no"]
[477,0,"chr1","+",1517070,1517775,"ENST00000439513",2,403,"ENSG00000197785","ATAD3A","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0005739(mitochondrion);GO:0005743(mitochondrial inner membrane);GO:0043066(negative regulation of apoptotic process);GO:0016049(cell growth);GO:0042645(mitochondrial nucleoid)","NA","NA","NA","ATPase family, AAA domain containing 3A [Source:HGNC Symbol;Acc:HGNC:25567]",0,0,1,0,1,1,"no","no"]
[79154,0,"chr17","-",8146640,8147549,"ENST00000585095",3,691,"MSTRG.6416","PER1","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0031490(chromatin DNA binding);GO:0007623(circadian rhythm);GO:0048511(rhythmic process);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0031625(ubiquitin protein ligase binding);GO:0043967(histone H4 acetylation);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0045892(negative regulation of transcription, DNA-templated);GO:0046329(negative regulation of JNK cascade);GO:0032922(circadian regulation of gene expression);GO:0042634(regulation of hair cycle);GO:2000323(negative regulation of glucocorticoid receptor signaling pathway);GO:0070888(E-box binding);GO:0043124(negative regulation of I-kappaB kinase/NF-kappaB signaling);GO:0000989(transcription factor activity, transcription factor binding);GO:0042752(regulation of circadian rhythm);GO:0070932(histone H3 deacetylation);GO:0097167(circadian regulation of translation);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:0000976(transcription regulatory region sequence-specific DNA binding);GO:0008134(transcription factor binding);GO:0019900(kinase binding);GO:0002028(regulation of sodium ion transport);GO:0009416(response to light stimulus);GO:0009649(entrainment of circadian clock);GO:0010608(posttranscriptional regulation of gene expression);GO:0043153(entrainment of circadian clock by photoperiod);GO:0043966(histone H3 acetylation);GO:0051591(response to cAMP);GO:1900015(regulation of cytokine production involved in inflammatory response);GO:1900744(regulation of p38MAPK cascade);GO:0005515(protein binding)","04710(Circadian rhythm);04713(Circadian entrainment);05168(Herpes simplex infection)","NA","NA","period circadian clock 1 [Source:HGNC Symbol;Acc:HGNC:8845]",{"v":0.00673,"d":"0.01"},0,"inf","inf",1,1,"up","no"]
[162065,0,"chr5","-",179862743,179867302,"ENST00000520794",3,2958,"MSTRG.12610","TBC1D9B","GO:0005509(calcium ion binding);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005096(GTPase activator activity);GO:0017137(Rab GTPase binding);GO:0006886(intracellular protein transport);GO:0031338(regulation of vesicle fusion);GO:0090630(activation of GTPase activity);GO:0005622(intracellular);GO:0012505(endomembrane system);GO:0005515(protein binding)","NA","NA","NA","TBC1 domain family member 9B [Source:HGNC Symbol;Acc:HGNC:29097]",{"v":0.156702,"d":"0.16"},{"v":0.042299,"d":"0.04"},{"v":3.70462658691695,"d":"3.70"},{"v":1.88932813136976,"d":"1.89"},1,1,"up","no"]
[23652,0,"chr10","-",114431113,114526931,"ENST00000392952",18,6841,"MSTRG.1996","ABLIM1","GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0003779(actin binding);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0007010(cytoskeleton organization);GO:0007601(visual perception);GO:0015629(actin cytoskeleton);GO:0009887(animal organ morphogenesis);GO:0030032(lamellipodium assembly);GO:0060271(cilium assembly);GO:0001725(stress fiber);GO:0030027(lamellipodium)","04360(Axon guidance)","K07520","NA","actin binding LIM protein 1 [Source:HGNC Symbol;Acc:HGNC:78]",{"v":0.155208,"d":"0.16"},{"v":0.013384,"d":"0.01"},{"v":11.596533173939,"d":"11.60"},{"v":3.53562166573068,"d":"3.54"},1,1,"up","no"]
[87722,0,"chr17","+",74763030,74768559,"ENST00000578958",4,714,"MSTRG.7184","SLC9A3R1","GO:0032947(protein complex scaffold);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005886(plasma membrane);GO:0042995(cell projection);GO:0005515(protein binding);GO:0016055(Wnt signaling pathway);GO:0048471(perinuclear region of cytoplasm);GO:0030175(filopodium);GO:0070062(extracellular exosome);GO:0071944(cell periphery);GO:0008285(negative regulation of cell proliferation);GO:0012505(endomembrane system);GO:0019902(phosphatase binding);GO:0005902(microvillus);GO:0005102(receptor binding);GO:0008360(regulation of cell shape);GO:0017081(chloride channel regulator activity);GO:0001726(ruffle);GO:0016324(apical plasma membrane);GO:0031982(vesicle);GO:0006461(protein complex assembly);GO:0015629(actin cytoskeleton);GO:2001244(positive regulation of intrinsic apoptotic signaling pathway);GO:0051683(establishment of Golgi localization);GO:0031528(microvillus membrane);GO:0008013(beta-catenin binding);GO:0030165(PDZ domain binding);GO:0070373(negative regulation of ERK1 and ERK2 cascade);GO:0019904(protein domain specific binding);GO:0031698(beta-2 adrenergic receptor binding);GO:0032403(protein complex binding);GO:0043621(protein self-association);GO:0045159(myosin II binding);GO:0050780(dopamine receptor binding);GO:0070851(growth factor receptor binding);GO:0003096(renal sodium ion transport);GO:0007191(adenylate cyclase-activating dopamine receptor signaling pathway);GO:0007605(sensory perception of sound);GO:0008361(regulation of cell size);GO:0010642(negative regulation of platelet-derived growth factor receptor signaling pathway);GO:0010766(negative regulation of sodium ion transport);GO:0014067(negative regulation of phosphatidylinositol 3-kinase signaling);GO:0019933(cAMP-mediated signaling);GO:0022612(gland morphogenesis);GO:0030033(microvillus assembly);GO:0030036(actin cytoskeleton organization);GO:0030336(negative regulation of cell migration);GO:0030643(cellular phosphate ion homeostasis);GO:0032415(regulation of sodium:proton antiporter activity);GO:0032416(negative regulation of sodium:proton antiporter activity);GO:0032782(bile acid secretion);GO:0034613(cellular protein localization);GO:0034635(glutathione transport);GO:0035414(negative regulation of catenin import into nucleus);GO:0040023(establishment of nucleus localization);GO:0044062(regulation of excretion);GO:0045198(establishment of epithelial cell apical/basal polarity);GO:0045859(regulation of protein kinase activity);GO:0045930(negative regulation of mitotic cell cycle);GO:0051898(negative regulation of protein kinase B signaling);GO:0060088(auditory receptor cell stereocilium organization);GO:0060158(phospholipase C-activating dopamine receptor signaling pathway);GO:0070293(renal absorption);GO:0090002(establishment of protein localization to plasma membrane);GO:0097291(renal phosphate ion absorption);GO:2000146(negative regulation of cell motility);GO:0031526(brush border membrane);GO:0032420(stereocilium);GO:0032426(stereocilium tip);GO:0045121(membrane raft);GO:0045177(apical part of cell);GO:0097225(sperm midpiece)","04530(Tight junction);05165(Human papillomavirus infection)","NA","NA","SLC9A3 regulator 1 [Source:HGNC Symbol;Acc:HGNC:11075]",{"v":0.086573,"d":"0.09"},{"v":0.056198,"d":"0.06"},{"v":1.54049966190968,"d":"1.54"},{"v":0.623398365751956,"d":"0.62"},1,1,"up","no"]
[47942,0,"chr12","+",122974752,122979438,"ENST00000545612",7,1465,"MSTRG.3844","OGFOD2","GO:0046872(metal ion binding);GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0005506(iron ion binding);GO:0016705(oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen);GO:0031418(L-ascorbic acid binding);GO:0051213(dioxygenase activity)","NA","NA","NA","2-oxoglutarate and iron dependent oxygenase domain containing 2 [Source:HGNC Symbol;Acc:HGNC:25823]",{"v":0.368058,"d":"0.37"},{"v":0.375175,"d":"0.38"},{"v":0.981030185913241,"d":"0.98"},{"v":-0.0276305666005077,"d":"-0.03"},1,1,"down","no"]
[183623,0,"chr8","+",47260936,47388484,"ENST00000522900",6,692,"MSTRG.14343","SPIDR","GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0006281(DNA repair);GO:0006310(DNA recombination);GO:0006974(cellular response to DNA damage stimulus);GO:0005515(protein binding);GO:0010569(regulation of double-strand break repair via homologous recombination);GO:0000724(double-strand break repair via homologous recombination);GO:0031334(positive regulation of protein complex assembly);GO:0000228(nuclear chromosome);GO:0071479(cellular response to ionizing radiation);GO:0072711(cellular response to hydroxyurea);GO:0072757(cellular response to camptothecin);GO:2000781(positive regulation of double-strand break repair);GO:0070202(regulation of establishment of protein localization to chromosome)","NA","NA","NA","scaffolding protein involved in DNA repair [Source:HGNC Symbol;Acc:HGNC:28971]",0,0,1,0,1,1,"no","no"]
[163608,0,"chr6","+",27957241,27958182,"ENST00000244623",1,942,"ENSG00000124657","OR2B6","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0004930(G-protein coupled receptor activity);GO:0007186(G-protein coupled receptor signaling pathway);GO:0005886(plasma membrane);GO:0004871(signal transducer activity);GO:0007165(signal transduction);GO:0004984(olfactory receptor activity);GO:0007608(sensory perception of smell);GO:0050896(response to stimulus);GO:0050911(detection of chemical stimulus involved in sensory perception of smell)","04740(Olfactory transduction)","K04257","NA","olfactory receptor family 2 subfamily B member 6 [Source:HGNC Symbol;Acc:HGNC:8241]",{"v":0.056017,"d":"0.06"},0,"inf","inf",1,1,"up","no"]
[105326,0,"chr19","-",54040834,54063953,"ENST00000366170",6,654,"MSTRG.8398","VSTM1","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005576(extracellular region);GO:0005125(cytokine activity);GO:0005615(extracellular space);GO:0002376(immune system process)","NA","NA","NA","V-set and transmembrane domain containing 1 [Source:HGNC Symbol;Acc:HGNC:29455]",0,{"v":0.13868,"d":"0.14"},"-inf","-inf",1,1,"down","no"]
[166709,0,"chr6","+",53078865,53092691,"ENST00000484812",4,543,"MSTRG.13095","FBXO9","GO:0005737(cytoplasm);GO:0016567(protein ubiquitination);GO:0005515(protein binding);GO:0005829(cytosol);GO:0000209(protein polyubiquitination);GO:0043687(post-translational protein modification);GO:0004842(ubiquitin-protein transferase activity);GO:0000151(ubiquitin ligase complex);GO:0032006(regulation of TOR signaling);GO:0019005(SCF ubiquitin ligase complex);GO:0031146(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process);GO:0045087(innate immune response);GO:0045444(fat cell differentiation)","NA","NA","NA","F-box protein 9 [Source:HGNC Symbol;Acc:HGNC:13588]",0,{"v":0.000258,"d":"0.00"},"-inf","-inf",1,1,"down","no"]
[27268,0,"chr11","-",18511043,18511475,"ENST00000538408",1,433,"MSTRG.2298","AC027544.1","NA","NA","NA","NA","NA",{"v":0.121866,"d":"0.12"},0,"inf","inf",1,1,"up","no"]
[94541,0,"chr19","-",2078374,2096479,"ENST00000591236",3,556,"MSTRG.7628","MOB3A","GO:0046872(metal ion binding);GO:0005622(intracellular)","NA","NA","NA","MOB kinase activator 3A [Source:HGNC Symbol;Acc:HGNC:29802]",0,{"v":0.206908,"d":"0.21"},"-inf","-inf",1,1,"down","no"]
[110213,0,"chr2","+",63588985,63590974,"ENST00000462944",2,634,"MSTRG.8737","MDH1","GO:0005737(cytoplasm);GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0006099(tricarboxylic acid cycle);GO:0003824(catalytic activity);GO:0005975(carbohydrate metabolic process);GO:0016616(oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor);GO:0005515(protein binding);GO:0005615(extracellular space);GO:0016615(malate dehydrogenase activity);GO:0030060(L-malate dehydrogenase activity);GO:0006108(malate metabolic process);GO:0019752(carboxylic acid metabolic process);GO:0005739(mitochondrion);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0006094(gluconeogenesis);GO:0004470(malic enzyme activity);GO:0047860(diiodophenylpyruvate reductase activity);GO:0006107(oxaloacetate metabolic process);GO:0006734(NADH metabolic process);GO:0051287(NAD binding);GO:0019674(NAD metabolic process);GO:0043209(myelin sheath)","00020(Citrate cycle (TCA cycle));00620(Pyruvate metabolism);00630(Glyoxylate and dicarboxylate metabolism);00270(Cysteine and methionine metabolism);04964(Proximal tubule bicarbonate reclamation)","NA","NA","malate dehydrogenase 1 [Source:HGNC Symbol;Acc:HGNC:6970]",{"v":0.562568,"d":"0.56"},{"v":0.080005,"d":"0.08"},{"v":7.03166052121742,"d":"7.03"},{"v":2.81386542085411,"d":"2.81"},1,1,"up","no"]
[133424,0,"chr3","-",11833026,11846885,"ENST00000417723",5,992,"ENSG00000144559","TAMM41","GO:0016020(membrane);GO:0016740(transferase activity);GO:0005743(mitochondrial inner membrane);GO:0006629(lipid metabolic process);GO:0005739(mitochondrion);GO:0008654(phospholipid biosynthetic process);GO:0016779(nucleotidyltransferase activity);GO:0032049(cardiolipin biosynthetic process);GO:0004605(phosphatidate cytidylyltransferase activity);GO:0016024(CDP-diacylglycerol biosynthetic process);GO:0031314(extrinsic component of mitochondrial inner membrane)","NA","NA","NA","TAM41 mitochondrial translocator assembly and maintenance homolog [Source:HGNC Symbol;Acc:HGNC:25187]",{"v":0.377431,"d":"0.38"},{"v":0.040636,"d":"0.04"},{"v":9.28809430062014,"d":"9.29"},{"v":3.21538261974293,"d":"3.22"},1,1,"up","no"]
[201140,0,"chrX","-",154271265,154295211,"ENST00000619903",5,1549,"ENSG00000278057","TEX28","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0003674(molecular_function);GO:0008150(biological_process)","NA","NA","NA","testis expressed 28 [Source:HGNC Symbol;Acc:HGNC:2563]",0,{"v":0.016427,"d":"0.02"},"-inf","-inf",1,1,"down","no"]
[188114,0,"chr8","-",143790925,143804151,"ENST00000526832",14,2189,"ENSG00000180900","SCRIB","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005654(nucleoplasm);GO:0005886(plasma membrane);GO:0030054(cell junction);GO:0042995(cell projection);GO:0005515(protein binding);GO:0007275(multicellular organism development);GO:0045211(postsynaptic membrane);GO:0030154(cell differentiation);GO:0098793(presynapse);GO:0045296(cadherin binding);GO:0030027(lamellipodium);GO:0031252(cell leading edge);GO:0070062(extracellular exosome);GO:0016323(basolateral plasma membrane);GO:0008283(cell proliferation);GO:0090630(activation of GTPase activity);GO:0005912(adherens junction);GO:0043065(positive regulation of apoptotic process);GO:0016032(viral process);GO:0046037(GMP metabolic process);GO:0046710(GDP metabolic process);GO:0007268(chemical synaptic transmission);GO:0016477(cell migration);GO:0042734(presynaptic membrane);GO:0005911(cell-cell junction);GO:0045930(negative regulation of mitotic cell cycle);GO:0001843(neural tube closure);GO:0016337(single organismal cell-cell adhesion);GO:0050918(positive chemotaxis);GO:0001921(positive regulation of receptor recycling);GO:0005913(cell-cell adherens junction);GO:0060603(mammary gland duct morphogenesis);GO:0071896(protein localization to adherens junction);GO:0014069(postsynaptic density);GO:0060561(apoptotic process involved in morphogenesis);GO:0008328(ionotropic glutamate receptor complex);GO:0004385(guanylate kinase activity);GO:0035255(ionotropic glutamate receptor binding);GO:0045197(establishment or maintenance of epithelial cell apical/basal polarity);GO:0097120(receptor localization to synapse);GO:0043113(receptor clustering);GO:0002093(auditory receptor cell morphogenesis);GO:0008105(asymmetric protein localization);GO:0016080(synaptic vesicle targeting);GO:0016331(morphogenesis of embryonic epithelium);GO:0021747(cochlear nucleus development);GO:0035089(establishment of apical/basal cell polarity);GO:0042060(wound healing);GO:0043615(astrocyte cell migration);GO:0048488(synaptic vesicle endocytosis);GO:0060088(auditory receptor cell stereocilium organization);GO:0098887(neurotransmitter receptor transport, endosome to postsynaptic membrane);GO:0098968(neurotransmitter receptor transport postsynaptic membrane to endosome);GO:0034750(Scrib-APC-beta-catenin complex);GO:0035748(myelin sheath abaxonal region);GO:0044291(cell-cell contact zone)","04390(Hippo signaling pathway);04530(Tight junction);05203(Viral carcinogenesis);05165(Human papillomavirus infection)","NA","NA","scribbled planar cell polarity protein [Source:HGNC Symbol;Acc:HGNC:30377]",{"v":0.033414,"d":"0.03"},0,"inf","inf",1,1,"up","no"]
[191337,0,"chr9","+",83623168,83643767,"ENST00000376417",4,511,"ENSG00000148057","IDNK","GO:0016301(kinase activity);GO:0005975(carbohydrate metabolic process);GO:0016310(phosphorylation);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0016740(transferase activity);GO:0003674(molecular_function);GO:0008150(biological_process);GO:0046316(gluconokinase activity);GO:0046177(D-gluconate catabolic process)","00030(Pentose phosphate pathway)","NA","NA","IDNK, gluconokinase [Source:HGNC Symbol;Acc:HGNC:31367]",0,{"v":0.031174,"d":"0.03"},"-inf","-inf",1,1,"down","no"]
[48806,0,"chr12","+",133130611,133151866,"ENST00000536877",5,472,"ENSG00000256223","ZNF10","GO:0003676(nucleic acid binding);GO:0006355(regulation of transcription, DNA-templated);GO:0005622(intracellular);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0005515(protein binding)","NA","NA","NA","zinc finger protein 10 [Source:HGNC Symbol;Acc:HGNC:12879]",0,{"v":0.017851,"d":"0.02"},"-inf","-inf",1,1,"down","no"]
[40396,0,"chr12","+",40312714,40320062,"ENST00000481256",4,561,"MSTRG.3288","LRRK2","GO:0001934(positive regulation of protein phosphorylation);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0043231(intracellular membrane-bounded organelle);GO:0005525(GTP binding);GO:0007264(small GTPase mediated signal transduction);GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0005634(nucleus);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0005743(mitochondrial inner membrane);GO:0005794(Golgi apparatus);GO:0005783(endoplasmic reticulum);GO:0005739(mitochondrion);GO:0042803(protein homodimerization activity);GO:0043547(positive regulation of GTPase activity);GO:0042995(cell projection);GO:0005515(protein binding);GO:0005615(extracellular space);GO:0030054(cell junction);GO:0045202(synapse);GO:0005741(mitochondrial outer membrane);GO:0030154(cell differentiation);GO:0006914(autophagy);GO:0031410(cytoplasmic vesicle);GO:0005759(mitochondrial matrix);GO:0005096(GTPase activator activity);GO:0005764(lysosome);GO:0030425(dendrite);GO:0042802(identical protein binding);GO:0098794(postsynapse);GO:0005768(endosome);GO:0030424(axon);GO:0005829(cytosol);GO:0048812(neuron projection morphogenesis);GO:0043204(perikaryon);GO:0070062(extracellular exosome);GO:0010508(positive regulation of autophagy);GO:0044325(ion channel binding);GO:0031398(positive regulation of protein ubiquitination);GO:0000165(MAPK cascade);GO:0030276(clathrin binding);GO:0042391(regulation of membrane potential);GO:0046777(protein autophosphorylation);GO:0007005(mitochondrion organization);GO:0030672(synaptic vesicle membrane);GO:0007528(neuromuscular junction development);GO:0032436(positive regulation of proteasomal ubiquitin-dependent protein catabolic process);GO:0060070(canonical Wnt signaling pathway);GO:0030426(growth cone);GO:0043005(neuron projection);GO:0005886(plasma membrane);GO:0043195(terminal bouton);GO:0007030(Golgi organization);GO:1901214(regulation of neuron death);GO:0017048(Rho GTPase binding);GO:0018105(peptidyl-serine phosphorylation);GO:1903206(negative regulation of hydrogen peroxide-induced cell death);GO:0018107(peptidyl-threonine phosphorylation);GO:0034599(cellular response to oxidative stress);GO:1901215(negative regulation of neuron death);GO:1902236(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway);GO:0003779(actin binding);GO:0032092(positive regulation of protein binding);GO:0060828(regulation of canonical Wnt signaling pathway);GO:0071287(cellular response to manganese ion);GO:1902803(regulation of synaptic vesicle transport);GO:1903351(cellular response to dopamine);GO:0043025(neuronal cell body);GO:1990909(Wnt signalosome);GO:0032839(dendrite cytoplasm);GO:0039706(co-receptor binding);GO:0032091(negative regulation of protein binding);GO:0005622(intracellular);GO:1903215(negative regulation of protein targeting to mitochondrion);GO:0006979(response to oxidative stress);GO:0043068(positive regulation of programmed cell death);GO:0015631(tubulin binding);GO:0008340(determination of adult lifespan);GO:0010506(regulation of autophagy);GO:0008017(microtubule binding);GO:0090140(regulation of mitochondrial fission);GO:0009267(cellular response to starvation);GO:0003924(GTPase activity);GO:0046039(GTP metabolic process);GO:2000300(regulation of synaptic vesicle exocytosis);GO:0000149(SNARE binding);GO:0017075(syntaxin-1 binding);GO:0051966(regulation of synaptic transmission, glutamatergic);GO:0061001(regulation of dendritic spine morphogenesis);GO:0000187(activation of MAPK activity);GO:0016242(negative regulation of macroautophagy);GO:0060161(positive regulation of dopamine receptor signaling pathway);GO:0000186(activation of MAPKK activity);GO:0016234(inclusion body);GO:0010955(negative regulation of protein processing);GO:0035556(intracellular signal transduction);GO:0031966(mitochondrial membrane);GO:0006897(endocytosis);GO:0044753(amphisome);GO:0044754(autolysosome);GO:0090263(positive regulation of canonical Wnt signaling pathway);GO:0060079(excitatory postsynaptic potential);GO:1904713(beta-catenin destruction complex binding);GO:0004708(MAP kinase kinase activity);GO:0030159(receptor signaling complex scaffold activity);GO:0034211(GTP-dependent protein kinase activity);GO:0036479(peroxidase inhibitor activity);GO:0051018(protein kinase A binding);GO:0001933(negative regulation of protein phosphorylation);GO:0007040(lysosome organization);GO:0010738(regulation of protein kinase A signaling);GO:0014041(regulation of neuron maturation);GO:0019722(calcium-mediated signaling);GO:0021772(olfactory bulb development);GO:0022028(tangential migration from the subventricular zone to the olfactory bulb);GO:0034260(negative regulation of GTPase activity);GO:0034613(cellular protein localization);GO:0035564(regulation of kidney size);GO:0035640(exploration behavior);GO:0035641(locomotory exploration behavior);GO:0035751(regulation of lysosomal lumen pH);GO:0040012(regulation of locomotion);GO:0043406(positive regulation of MAP kinase activity);GO:0048312(intracellular distribution of mitochondria);GO:0051646(mitochondrion localization);GO:0051900(regulation of mitochondrial depolarization);GO:0060159(regulation of dopamine receptor signaling pathway);GO:0070585(protein localization to mitochondrion);GO:0070997(neuron death);GO:0071407(cellular response to organic cyclic compound);GO:0072593(reactive oxygen species metabolic process);GO:0090394(negative regulation of excitatory postsynaptic potential);GO:1902499(positive regulation of protein autoubiquitination);GO:1902692(regulation of neuroblast proliferation);GO:1902823(negative regulation of late endosome to lysosome transport);GO:1902902(negative regulation of autophagosome assembly);GO:1903125(negative regulation of thioredoxin peroxidase activity by peptidyl-threonine phosphorylation);GO:1903217(negative regulation of protein processing involved in protein targeting to mitochondrion);GO:1904887(Wnt signalosome assembly);GO:1905279(regulation of retrograde transport, endosome to Golgi);GO:1905289(regulation of CAMKK-AMPK signaling cascade);GO:2000172(regulation of branching morphogenesis of a nerve);GO:0005798(Golgi-associated vesicle);GO:0005802(trans-Golgi network);GO:0005902(microvillus);GO:0008021(synaptic vesicle);GO:0030529(intracellular ribonucleoprotein complex);GO:0032473(cytoplasmic side of mitochondrial outer membrane);GO:0045121(membrane raft);GO:0097487(multivesicular body, internal vesicle);GO:0099400(caveola neck)","05012(Parkinson's disease)","NA","NA","leucine rich repeat kinase 2 [Source:HGNC Symbol;Acc:HGNC:18618]",{"v":0.747625,"d":"0.75"},{"v":0.094365,"d":"0.09"},{"v":7.92269379536905,"d":"7.92"},{"v":2.98599104450317,"d":"2.99"},1,1,"up","no"]
[35517,0,"chr11","+",117201166,117204760,"ENST00000533863",2,3298,"MSTRG.2884","TAGLN","GO:0005737(cytoplasm);GO:0051015(actin filament binding);GO:0003779(actin binding);GO:0005515(protein binding);GO:0030855(epithelial cell differentiation);GO:0007517(muscle organ development)","NA","NA","NA","transgelin [Source:HGNC Symbol;Acc:HGNC:11553]",{"v":0.147627,"d":"0.15"},{"v":0.077148,"d":"0.08"},{"v":1.91355576294914,"d":"1.91"},{"v":0.936255943210742,"d":"0.94"},1,1,"up","no"]
[25498,0,"chr11","-",3019190,3029057,"ENST00000465240",4,658,"ENSG00000110619","CARS","GO:0005737(cytoplasm);GO:0006412(translation);GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0005829(cytosol);GO:0042803(protein homodimerization activity);GO:0016874(ligase activity);GO:0004812(aminoacyl-tRNA ligase activity);GO:0006418(tRNA aminoacylation for protein translation);GO:0000049(tRNA binding);GO:0004817(cysteine-tRNA ligase activity);GO:0006423(cysteinyl-tRNA aminoacylation);GO:0005515(protein binding)","00970(Aminoacyl-tRNA biosynthesis)","NA","NA","cysteinyl-tRNA synthetase [Source:HGNC Symbol;Acc:HGNC:1493]",0,{"v":0.106189,"d":"0.11"},"-inf","-inf",1,1,"down","no"]
[17403,0,"chr1","-",241590102,241601178,"ENST00000462265",4,795,"ENSG00000054277","OPN3","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0004930(G-protein coupled receptor activity);GO:0007186(G-protein coupled receptor signaling pathway);GO:0004871(signal transducer activity);GO:0007165(signal transduction);GO:0050896(response to stimulus);GO:0009881(photoreceptor activity);GO:0018298(protein-chromophore linkage);GO:0005887(integral component of plasma membrane);GO:0001750(photoreceptor outer segment);GO:0007602(phototransduction);GO:0008020(G-protein coupled photoreceptor activity);GO:0009584(detection of visible light);GO:0042752(regulation of circadian rhythm);GO:0009583(detection of light stimulus)","NA","NA","NA","opsin 3 [Source:HGNC Symbol;Acc:HGNC:14007]",{"v":0.005925,"d":"0.01"},0,"inf","inf",1,1,"up","no"]
[109026,0,"chr2","+",39436637,39604076,"ENST00000426083",9,1438,"ENSG00000231312","AC007388.1","NA","NA","NA","NA","NA",0,{"v":0.075093,"d":"0.08"},"-inf","-inf",1,1,"down","no"]
[89531,0,"chr17","+",81891772,81900254,"ENST00000579133",3,563,"MSTRG.7340","ANAPC11","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0005730(nucleolus);GO:0005654(nucleoplasm);GO:0016567(protein ubiquitination);GO:0051301(cell division);GO:0004842(ubiquitin-protein transferase activity);GO:0007049(cell cycle);GO:0005680(anaphase-promoting complex);GO:0005829(cytosol);GO:0031145(anaphase-promoting complex-dependent catabolic process);GO:0043161(proteasome-mediated ubiquitin-dependent protein catabolic process);GO:0051437(positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition);GO:0042787(protein ubiquitination involved in ubiquitin-dependent protein catabolic process);GO:0051436(negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle);GO:0051439(regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle);GO:0070979(protein K11-linked ubiquitination);GO:0000278(mitotic cell cycle);GO:0061630(ubiquitin protein ligase activity);GO:0034450(ubiquitin-ubiquitin ligase activity);GO:0097602(cullin family protein binding);GO:0045842(positive regulation of mitotic metaphase/anaphase transition)","04120(Ubiquitin mediated proteolysis);04110(Cell cycle);04114(Oocyte meiosis);04914(Progesterone-mediated oocyte maturation);05166(HTLV-I infection)","NA","NA","anaphase promoting complex subunit 11 [Source:HGNC Symbol;Acc:HGNC:14452]",{"v":0.210258,"d":"0.21"},{"v":0.118151,"d":"0.12"},{"v":1.77957021100118,"d":"1.78"},{"v":0.831528853929453,"d":"0.83"},1,1,"up","no"]
[49175,0,"chr13","+",25095868,25099254,"ENST00000281589",1,3387,"ENSG00000151846","PABPC3","GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0008143(poly(A) binding);GO:0016071(mRNA metabolic process)","03013(RNA transport);03015(mRNA surveillance pathway);03018(RNA degradation)","K13126","NA","poly(A) binding protein cytoplasmic 3 [Source:HGNC Symbol;Acc:HGNC:8556]",{"v":0.095814,"d":"0.10"},{"v":0.079009,"d":"0.08"},{"v":1.21269728765077,"d":"1.21"},{"v":0.278219471227157,"d":"0.28"},1,1,"up","no"]
[58867,0,"chr14","-",102228836,102305189,"ENST00000519569",11,2355,"MSTRG.4699","MOK","GO:0004672(protein kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0004674(protein serine/threonine kinase activity);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0042995(cell projection);GO:0051726(regulation of cell cycle);GO:0035556(intracellular signal transduction);GO:0005929(cilium);GO:0097546(ciliary base);GO:0010468(regulation of gene expression);GO:0007165(signal transduction);GO:0004693(cyclin-dependent protein serine/threonine kinase activity)","NA","NA","NA","MOK protein kinase [Source:HGNC Symbol;Acc:HGNC:9833]",{"v":0.009822,"d":"0.01"},0,"inf","inf",1,1,"up","no"]
[30585,0,"chr11","+",63939002,63954586,"ENST00000539656",5,577,"ENSG00000110583","NAA40","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016740(transferase activity);GO:0016746(transferase activity, transferring acyl groups);GO:0008080(N-acetyltransferase activity);GO:0006629(lipid metabolic process);GO:0043967(histone H4 acetylation);GO:0010485(H4 histone acetyltransferase activity);GO:0043968(histone H2A acetylation);GO:0006474(N-terminal protein amino acid acetylation);GO:0043998(H2A histone acetyltransferase activity);GO:1990189(peptide-serine-N-acetyltransferase activity)","NA","NA","NA","N(alpha)-acetyltransferase 40, NatD catalytic subunit [Source:HGNC Symbol;Acc:HGNC:25845]",0,0,1,0,1,1,"no","no"]
[48045,0,"chr12","+",123363868,123365787,"ENST00000602918",1,1920,"MSTRG.3835","AC137767.1","NA","NA","NA","NA","NA",{"v":0.010984,"d":"0.01"},{"v":0.020801,"d":"0.02"},{"v":0.528051535983847,"d":"0.53"},{"v":-0.921249356439958,"d":"-0.92"},1,1,"down","no"]
[130730,0,"chr22","+",35323868,35338788,"ENST00000491987",7,852,"MSTRG.10406","TOM1","GO:0005622(intracellular);GO:0006886(intracellular protein transport);GO:0006810(transport);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0015031(protein transport);GO:0005829(cytosol);GO:0005515(protein binding);GO:0005886(plasma membrane);GO:0005768(endosome);GO:0006897(endocytosis);GO:0070062(extracellular exosome);GO:0005769(early endosome);GO:0016197(endosomal transport);GO:0043312(neutrophil degranulation);GO:0035579(specific granule membrane);GO:0035577(azurophil granule membrane);GO:0030276(clathrin binding)","NA","NA","NA","target of myb1 membrane trafficking protein [Source:HGNC Symbol;Acc:HGNC:11982]",{"v":0.258853,"d":"0.26"},{"v":0.174998,"d":"0.17"},{"v":1.47917690487891,"d":"1.48"},{"v":0.564794604518907,"d":"0.56"},1,1,"up","no"]
[55604,0,"chr14","+",60249441,60288555,"ENST00000325658",4,4125,"MSTRG.4435","PPM1A","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0046872(metal ion binding);GO:0005829(cytosol);GO:0000287(magnesium ion binding);GO:0016787(hydrolase activity);GO:0003824(catalytic activity);GO:0005886(plasma membrane);GO:0006470(protein dephosphorylation);GO:0004721(phosphoprotein phosphatase activity);GO:0005515(protein binding);GO:0004871(signal transducer activity);GO:0030145(manganese ion binding);GO:0004722(protein serine/threonine phosphatase activity);GO:0043169(cation binding);GO:0005654(nucleoplasm);GO:0043123(positive regulation of I-kappaB kinase/NF-kappaB signaling);GO:0045893(positive regulation of transcription, DNA-templated);GO:0030177(positive regulation of Wnt signaling pathway);GO:0043124(negative regulation of I-kappaB kinase/NF-kappaB signaling);GO:0070412(R-SMAD binding);GO:0010991(negative regulation of SMAD protein complex assembly);GO:0030512(negative regulation of transforming growth factor beta receptor signaling pathway);GO:0035970(peptidyl-threonine dephosphorylation);GO:0007050(cell cycle arrest);GO:0016055(Wnt signaling pathway);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0006499(N-terminal protein myristoylation);GO:0042347(negative regulation of NF-kappaB import into nucleus);GO:0033192(calmodulin-dependent protein phosphatase activity);GO:0016311(dephosphorylation);GO:0030514(negative regulation of BMP signaling pathway);GO:0046827(positive regulation of protein export from nucleus);GO:0071560(cellular response to transforming growth factor beta stimulus)","04010(MAPK signaling pathway)","K04457","EC:3.1.3.16","protein phosphatase, Mg2+/Mn2+ dependent 1A [Source:HGNC Symbol;Acc:HGNC:9275]",{"v":2.179811,"d":"2.18"},{"v":0.100724,"d":"0.10"},{"v":21.6414260752154,"d":"21.64"},{"v":4.43572366447045,"d":"4.44"},1,1,"up","no"]
[73626,0,"chr16","+",57639413,57651605,"ENST00000566888",3,720,"MSTRG.5971","ADGRG1","GO:0005622(intracellular);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0004930(G-protein coupled receptor activity);GO:0007186(G-protein coupled receptor signaling pathway);GO:0007155(cell adhesion);GO:0005886(plasma membrane);GO:0004871(signal transducer activity);GO:0007165(signal transduction);GO:0005576(extracellular region);GO:0004888(transmembrane signaling receptor activity);GO:0007166(cell surface receptor signaling pathway);GO:0007275(multicellular organism development);GO:0007399(nervous system development);GO:0030154(cell differentiation);GO:0045121(membrane raft);GO:0008201(heparin binding);GO:0070062(extracellular exosome);GO:0050840(extracellular matrix binding);GO:0008285(negative regulation of cell proliferation);GO:0005887(integral component of plasma membrane);GO:0007267(cell-cell signaling);GO:0045785(positive regulation of cell adhesion);GO:0016477(cell migration);GO:0001525(angiogenesis);GO:0007266(Rho protein signal transduction);GO:0005518(collagen binding);GO:0070528(protein kinase C signaling);GO:0035025(positive regulation of Rho protein signal transduction);GO:2001223(negative regulation of neuron migration);GO:0021819(layer formation in cerebral cortex);GO:0021801(cerebral cortex radial glia guided migration);GO:0007420(brain development);GO:0010573(vascular endothelial growth factor production);GO:0097451(glial limiting end-foot);GO:0021796(cerebral cortex regionalization);GO:0072520(seminiferous tubule development);GO:2000179(positive regulation of neural precursor cell proliferation)","NA","NA","NA","adhesion G protein-coupled receptor G1 [Source:HGNC Symbol;Acc:HGNC:4512]",0,{"v":3.163E-3,"d":"0.00"},"-inf","-inf",1,1,"down","no"]
[82720,0,"chr17","-",38850422,38853424,"ENST00000470646",4,333,"MSTRG.6767","RPL23","GO:0003723(RNA binding);GO:0016020(membrane);GO:0006412(translation);GO:0030529(intracellular ribonucleoprotein complex);GO:0003735(structural constituent of ribosome);GO:0005840(ribosome);GO:0005515(protein binding);GO:0005925(focal adhesion);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0031012(extracellular matrix);GO:0043234(protein complex);GO:0006413(translational initiation);GO:0006610(ribosomal protein import into nucleus);GO:0006364(rRNA processing);GO:0005737(cytoplasm);GO:0000184(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay);GO:0019083(viral transcription);GO:0006614(SRP-dependent cotranslational protein targeting to membrane);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0008284(positive regulation of cell proliferation);GO:0010628(positive regulation of gene expression);GO:0032986(protein-DNA complex disassembly);GO:0050821(protein stabilization);GO:0005654(nucleoplasm);GO:0071158(positive regulation of cell cycle arrest);GO:0072717(cellular response to actinomycin D);GO:0022625(cytosolic large ribosomal subunit);GO:0005730(nucleolus);GO:0031625(ubiquitin protein ligase binding);GO:0001223(transcription coactivator binding);GO:1990948(ubiquitin ligase inhibitor activity);GO:1904667(negative regulation of ubiquitin protein ligase activity);GO:2000059(negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process);GO:0070180(large ribosomal subunit rRNA binding);GO:0071157(negative regulation of cell cycle arrest);GO:1901798(positive regulation of signal transduction by p53 class mediator)","03010(Ribosome)","NA","NA","ribosomal protein L23 [Source:HGNC Symbol;Acc:HGNC:10316]",{"v":0.517812,"d":"0.52"},{"v":0.532108,"d":"0.53"},{"v":0.973133273696317,"d":"0.97"},{"v":-0.0392906946765183,"d":"-0.04"},1,1,"down","no"]
[198707,0,"chrX","+",93674013,93712274,"ENST00000322139",3,3292,"ENSG00000179083","FAM133A","GO:0005515(protein binding)","NA","NA","NA","family with sequence similarity 133 member A [Source:HGNC Symbol;Acc:HGNC:26748]",0,{"v":0.014231,"d":"0.01"},"-inf","-inf",1,1,"down","no"]
[191546,0,"chr9","-",88484852,88485325,"ENST00000440753",1,474,"ENSG00000231804","AL353748.1","NA","NA","NA","NA","NA",{"v":0.112067,"d":"0.11"},0,"inf","inf",1,1,"up","no"]
[44131,0,"chr12","-",68380435,68383605,"ENST00000536094",2,437,"ENSG00000251301","LINC02384","NA","NA","NA","NA","long intergenic non-protein coding RNA 2384 [Source:HGNC Symbol;Acc:HGNC:53308]",{"v":0.634957,"d":"0.63"},{"v":0.673194,"d":"0.67"},{"v":0.943200622703114,"d":"0.94"},{"v":-0.0843634240989512,"d":"-0.08"},1,1,"down","no"]
[156337,0,"chr5","+",82111392,82276297,"ENST00000508814",4,413,"MSTRG.12169","ATG10","GO:0006810(transport);GO:0005737(cytoplasm);GO:0015031(protein transport);GO:0016874(ligase activity);GO:0006914(autophagy);GO:0005829(cytosol);GO:0006497(protein lipidation);GO:0032446(protein modification by small protein conjugation);GO:0005622(intracellular);GO:0016236(macroautophagy);GO:0006983(ER overload response);GO:0031401(positive regulation of protein modification process);GO:0019777(Atg12 transferase activity)","04140(Autophagy - animal);04136(Autophagy - other eukaryotes)","NA","NA","autophagy related 10 [Source:HGNC Symbol;Acc:HGNC:20315]",0,{"v":0.005279,"d":"0.01"},"-inf","-inf",1,1,"down","no"]
[200951,0,"chrX","-",153735626,153766453,"ENST00000434284",3,914,"MSTRG.15488","U52111.1","NA","NA","NA","NA","NA",0,0,1,0,1,1,"no","no"]
[163866,0,"chr6","+",29724417,29726528,"ENST00000606273",5,579,"MSTRG.12784","HLA-F","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005783(endoplasmic reticulum);GO:0002376(immune system process);GO:0050776(regulation of immune response);GO:0005886(plasma membrane);GO:0002474(antigen processing and presentation of peptide antigen via MHC class I);GO:0042612(MHC class I protein complex);GO:0002479(antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent);GO:0030670(phagocytic vesicle membrane);GO:0009986(cell surface);GO:0000139(Golgi membrane);GO:0060333(interferon-gamma-mediated signaling pathway);GO:0012507(ER to Golgi transport vesicle membrane);GO:0060337(type I interferon signaling pathway);GO:0005102(receptor binding);GO:0046978(TAP1 binding);GO:0046979(TAP2 binding);GO:0071556(integral component of lumenal side of endoplasmic reticulum membrane);GO:0031901(early endosome membrane);GO:0002480(antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent);GO:0055038(recycling endosome membrane);GO:0042605(peptide antigen binding)","04514(Cell adhesion molecules (CAMs));04144(Endocytosis);04145(Phagosome);04218(Cellular senescence);04650(Natural killer cell mediated cytotoxicity);04612(Antigen processing and presentation);05203(Viral carcinogenesis);05320(Autoimmune thyroid disease);05330(Allograft rejection);05332(Graft-versus-host disease);05416(Viral myocarditis);04940(Type I diabetes mellitus);05166(HTLV-I infection);05168(Herpes simplex infection);05167(Kaposi's sarcoma-associated herpesvirus infection);05169(Epstein-Barr virus infection);05165(Human papillomavirus infection)","NA","NA","major histocompatibility complex, class I, F [Source:HGNC Symbol;Acc:HGNC:4963]",0,0,1,0,1,1,"no","no"]
[132503,0,"chr22","-",50274979,50278840,"ENST00000479818",8,1916,"MSTRG.10594","PLXNB2","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0007165(signal transduction);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0007275(multicellular organism development);GO:0017154(semaphorin receptor activity);GO:0071526(semaphorin-plexin signaling pathway);GO:0005887(integral component of plasma membrane);GO:0070062(extracellular exosome);GO:0008360(regulation of cell shape);GO:0043087(regulation of GTPase activity);GO:0009986(cell surface);GO:0007405(neuroblast proliferation);GO:0007420(brain development);GO:0001843(neural tube closure);GO:0001932(regulation of protein phosphorylation);GO:0007156(homophilic cell adhesion via plasma membrane adhesion molecules);GO:0007162(negative regulation of cell adhesion);GO:0010976(positive regulation of neuron projection development);GO:0050772(positive regulation of axonogenesis);GO:2001222(regulation of neuron migration)","04360(Axon guidance)","NA","NA","plexin B2 [Source:HGNC Symbol;Acc:HGNC:9104]",{"v":2.22E-4,"d":"0.00"},0,"inf","inf",1,1,"up","no"]
[131885,0,"chr22","-",42410277,42432362,"ENST00000355469",3,671,"MSTRG.10534","NFAM1","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005886(plasma membrane);GO:0004888(transmembrane signaling receptor activity);GO:0007166(cell surface receptor signaling pathway);GO:0043312(neutrophil degranulation);GO:0001819(positive regulation of cytokine production);GO:0045577(regulation of B cell differentiation);GO:0050861(positive regulation of B cell receptor signaling pathway);GO:0035577(azurophil granule membrane);GO:0035556(intracellular signal transduction);GO:0006954(inflammatory response);GO:0007165(signal transduction);GO:0051091(positive regulation of sequence-specific DNA binding transcription factor activity);GO:0030183(B cell differentiation);GO:0050853(B cell receptor signaling pathway);GO:0009986(cell surface);GO:0045121(membrane raft)","NA","NA","NA","NFAT activating protein with ITAM motif 1 [Source:HGNC Symbol;Acc:HGNC:29872]",{"v":1.304991,"d":"1.30"},{"v":0.410764,"d":"0.41"},{"v":3.17698483800917,"d":"3.18"},{"v":1.66765820488264,"d":"1.67"},1,1,"up","no"]
[154355,0,"chr5","+",38845999,38935641,"ENST00000274276",18,5539,"MSTRG.12009","OSMR","GO:0008284(positive regulation of cell proliferation);GO:0002675(positive regulation of acute inflammatory response);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0004896(cytokine receptor activity);GO:0005886(plasma membrane);GO:0019838(growth factor binding);GO:0034097(response to cytokine);GO:0038165(oncostatin-M-mediated signaling pathway);GO:0016324(apical plasma membrane);GO:0004924(oncostatin-M receptor activity);GO:0005900(oncostatin-M receptor complex)","04630(Jak-STAT signaling pathway);04151(PI3K-Akt signaling pathway);04060(Cytokine-cytokine receptor interaction)","K05057","NA","oncostatin M receptor [Source:HGNC Symbol;Acc:HGNC:8507]",0,0,1,0,1,1,"no","no"]
[74830,0,"chr16","+",68291286,68294747,"ENST00000562863",2,419,"MSTRG.6064","SLC7A6","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0043231(intracellular membrane-bounded organelle);GO:0005886(plasma membrane);GO:0015297(antiporter activity);GO:0015171(amino acid transmembrane transporter activity);GO:0003333(amino acid transmembrane transport);GO:0050900(leukocyte migration);GO:1902475(L-alpha-amino acid transmembrane transport);GO:0016323(basolateral plasma membrane);GO:0006865(amino acid transport);GO:0005887(integral component of plasma membrane);GO:0006461(protein complex assembly);GO:0006520(cellular amino acid metabolic process);GO:0015179(L-amino acid transmembrane transporter activity);GO:0015807(L-amino acid transport)","NA","NA","NA","solute carrier family 7 member 6 [Source:HGNC Symbol;Acc:HGNC:11064]",{"v":0.320037,"d":"0.32"},{"v":0.23179,"d":"0.23"},{"v":1.3807196168946,"d":"1.38"},{"v":0.46542038086705,"d":"0.47"},1,1,"up","no"]
[55675,0,"chr14","+",61281149,61449252,"ENST00000555906",5,459,"MSTRG.4455","PRKCH","GO:0004672(protein kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0005622(intracellular);GO:0046872(metal ion binding);GO:0035556(intracellular signal transduction);GO:0005737(cytoplasm);GO:0000166(nucleotide binding);GO:0004674(protein serine/threonine kinase activity);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0004697(protein kinase C activity);GO:0030154(cell differentiation);GO:0070062(extracellular exosome);GO:0018105(peptidyl-serine phosphorylation);GO:2000810(regulation of bicellular tight junction assembly);GO:0007165(signal transduction);GO:0019899(enzyme binding);GO:0051092(positive regulation of NF-kappaB transcription factor activity);GO:0030168(platelet activation);GO:0034351(negative regulation of glial cell apoptotic process);GO:0010744(positive regulation of macrophage derived foam cell differentiation);GO:0045618(positive regulation of keratinocyte differentiation);GO:1903078(positive regulation of protein localization to plasma membrane);GO:0050861(positive regulation of B cell receptor signaling pathway);GO:0004699(calcium-independent protein kinase C activity);GO:0017160(Ral GTPase binding);GO:0060252(positive regulation of glial cell proliferation);GO:0070528(protein kinase C signaling);GO:0005911(cell-cell junction);GO:0016020(membrane)","04270(Vascular smooth muscle contraction);04750(Inflammatory mediator regulation of TRP channels)","NA","NA","protein kinase C eta [Source:HGNC Symbol;Acc:HGNC:9403]",{"v":8e-05,"d":"0.00"},0,"inf","inf",1,1,"up","no"]
[66242,0,"chr15","-",89327013,89328712,"ENST00000532363",3,445,"MSTRG.5414","POLG","GO:0003677(DNA binding);GO:0006260(DNA replication);GO:0005760(gamma DNA polymerase complex);GO:0003676(nucleic acid binding);GO:0016740(transferase activity);GO:0005739(mitochondrion);GO:0090305(nucleic acid phosphodiester bond hydrolysis);GO:0005515(protein binding);GO:0016779(nucleotidyltransferase activity);GO:0003887(DNA-directed DNA polymerase activity);GO:0071897(DNA biosynthetic process);GO:0070062(extracellular exosome);GO:0003682(chromatin binding);GO:0043234(protein complex);GO:0007568(aging);GO:0009416(response to light stimulus);GO:0010332(response to gamma radiation);GO:0055093(response to hyperoxia);GO:0071333(cellular response to glucose stimulus);GO:0043195(terminal bouton);GO:0006259(DNA metabolic process);GO:0002020(protease binding);GO:0042645(mitochondrial nucleoid);GO:0006261(DNA-dependent DNA replication);GO:0008408(3'-5' exonuclease activity);GO:0006264(mitochondrial DNA replication);GO:0006287(base-excision repair, gap-filling)","NA","NA","NA","DNA polymerase gamma, catalytic subunit [Source:HGNC Symbol;Acc:HGNC:9179]",{"v":0.620552,"d":"0.62"},0,"inf","inf",1,1,"up","no"]
[84515,0,"chr17","+",45545900,45563230,"ENST00000586348",2,630,"ENSG00000267198","AC091132.5","NA","NA","NA","NA","NA",{"v":0.186443,"d":"0.19"},0,"inf","inf",1,1,"up","no"]
[10612,0,"chr1","-",150622731,150629576,"ENST00000339643",5,633,"MSTRG.921","ENSA","GO:0005737(cytoplasm);GO:0051301(cell division);GO:0050790(regulation of catalytic activity);GO:0005515(protein binding);GO:0043086(negative regulation of catalytic activity);GO:0007049(cell cycle);GO:0065009(regulation of molecular function);GO:0004864(protein phosphatase inhibitor activity);GO:0005654(nucleoplasm);GO:0006810(transport);GO:0005102(receptor binding);GO:0000278(mitotic cell cycle);GO:0007584(response to nutrient);GO:0008200(ion channel inhibitor activity);GO:0019212(phosphatase inhibitor activity);GO:0019870(potassium channel inhibitor activity);GO:0019888(protein phosphatase regulator activity);GO:0051721(protein phosphatase 2A binding);GO:0000086(G2/M transition of mitotic cell cycle);GO:0035308(negative regulation of protein dephosphorylation);GO:0050796(regulation of insulin secretion);GO:0009749(response to glucose)","NA","NA","NA","endosulfine alpha [Source:HGNC Symbol;Acc:HGNC:3360]",{"v":0.224649,"d":"0.22"},{"v":0.641195,"d":"0.64"},{"v":0.350359874921046,"d":"0.35"},{"v":-1.5130905356079,"d":"-1.51"},1,1,"down","no"]
[16894,0,"chr1","+",230261951,230264972,"ENST00000492568",2,2766,"MSTRG.1456","GALNT2","GO:0048471(perinuclear region of cytoplasm);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005794(Golgi apparatus);GO:0046872(metal ion binding);GO:0016740(transferase activity);GO:0030246(carbohydrate binding);GO:0016757(transferase activity, transferring glycosyl groups);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0000139(Golgi membrane);GO:0006486(protein glycosylation);GO:0032580(Golgi cisterna membrane);GO:0005789(endoplasmic reticulum membrane);GO:0070062(extracellular exosome);GO:0006493(protein O-linked glycosylation);GO:0016266(O-glycan processing);GO:0030145(manganese ion binding);GO:0004653(polypeptide N-acetylgalactosaminyltransferase activity);GO:0002378(immunoglobulin biosynthetic process);GO:0018242(protein O-linked glycosylation via serine);GO:0018243(protein O-linked glycosylation via threonine);GO:0005795(Golgi stack);GO:0030173(integral component of Golgi membrane)","00512(Mucin type O-glycan biosynthesis)","NA","NA","polypeptide N-acetylgalactosaminyltransferase 2 [Source:HGNC Symbol;Acc:HGNC:4124]",{"v":0.038001,"d":"0.04"},{"v":0.063774,"d":"0.06"},{"v":0.595869790196632,"d":"0.60"},{"v":-0.746930988295522,"d":"-0.75"},1,1,"down","no"]
[110142,0,"chr2","-",62500635,62506469,"ENST00000494919",3,2460,"ENSG00000186889","TMEM17","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005886(plasma membrane);GO:0042995(cell projection);GO:0007224(smoothened signaling pathway);GO:0060271(cilium assembly);GO:0005929(cilium);GO:0030030(cell projection organization);GO:0035869(ciliary transition zone);GO:0060170(ciliary membrane);GO:0036038(MKS complex);GO:1905515(non-motile cilium assembly)","NA","NA","NA","transmembrane protein 17 [Source:HGNC Symbol;Acc:HGNC:26623]",{"v":0.107824,"d":"0.11"},{"v":0.027538,"d":"0.03"},{"v":3.91546227031738,"d":"3.92"},{"v":1.96918264614313,"d":"1.97"},1,1,"up","no"]
[126563,0,"chr21","+",32298850,32312290,"ENST00000303645",3,935,"ENSG00000170262","MRAP","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0030819(positive regulation of cAMP biosynthetic process);GO:0031781(type 3 melanocortin receptor binding);GO:0031782(type 4 melanocortin receptor binding);GO:0070996(type 1 melanocortin receptor binding);GO:0034394(protein localization to cell surface);GO:0031780(corticotropin hormone receptor binding);GO:0031783(type 5 melanocortin receptor binding);GO:0050873(brown fat cell differentiation)","04927(Cortisol synthesis and secretion)","K22398","NA","melanocortin 2 receptor accessory protein [Source:HGNC Symbol;Acc:HGNC:1304]",0,0,1,0,1,1,"no","no"]
[97569,0,"chr19","-",14412610,14419073,"ENST00000590696",4,563,"MSTRG.7902","DDX39A","GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0006397(mRNA processing);GO:0008380(RNA splicing);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016607(nuclear speck);GO:0016020(membrane);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0016787(hydrolase activity);GO:0004386(helicase activity);GO:0005515(protein binding);GO:0006406(mRNA export from nucleus);GO:0042802(identical protein binding);GO:0005730(nucleolus);GO:0005654(nucleoplasm);GO:0006974(cellular response to DNA damage stimulus);GO:0004004(ATP-dependent RNA helicase activity);GO:0010501(RNA secondary structure unwinding);GO:0005681(spliceosomal complex);GO:0016887(ATPase activity);GO:0000398(mRNA splicing, via spliceosome);GO:0006369(termination of RNA polymerase II transcription);GO:0006405(RNA export from nucleus);GO:0010468(regulation of gene expression);GO:0031124(mRNA 3'-end processing)","NA","NA","NA","DExD-box helicase 39A [Source:HGNC Symbol;Acc:HGNC:17821]",0,{"v":0.05535,"d":"0.06"},"-inf","-inf",1,1,"down","no"]
[95111,0,"chr19","+",4475349,4502201,"ENST00000615225",15,3100,"ENSG00000167674","HDGFL2","GO:0005634(nucleus);GO:0005515(protein binding);GO:0030307(positive regulation of cell growth)","NA","NA","NA","HDGF like 2 [Source:HGNC Symbol;Acc:HGNC:14680]",{"v":0.138999,"d":"0.14"},{"v":0.165264,"d":"0.17"},{"v":0.841072465872786,"d":"0.84"},{"v":-0.249697988043826,"d":"-0.25"},1,1,"down","no"]
[146539,0,"chr4","+",26362476,26420838,"ENST00000511451",5,742,"MSTRG.11557","RBPJ","GO:0005634(nucleus);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:0000982(transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0060045(positive regulation of cardiac muscle cell proliferation);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0003151(outflow tract morphogenesis);GO:0030513(positive regulation of BMP signaling pathway);GO:0005737(cytoplasm);GO:0005654(nucleoplasm);GO:0006351(transcription, DNA-templated);GO:0005515(protein binding);GO:0006310(DNA recombination);GO:0007219(Notch signaling pathway);GO:0005730(nucleolus);GO:0043565(sequence-specific DNA binding);GO:0008134(transcription factor binding);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0045892(negative regulation of transcription, DNA-templated);GO:0006367(transcription initiation from RNA polymerase II promoter);GO:0001103(RNA polymerase II repressing transcription factor binding);GO:0001525(angiogenesis);GO:0030279(negative regulation of ossification);GO:0001837(epithelial to mesenchymal transition);GO:0003198(epithelial to mesenchymal transition involved in endocardial cushion formation);GO:2000138(positive regulation of cell proliferation involved in heart morphogenesis);GO:0061314(Notch signaling involved in heart development);GO:0070491(repressing transcription factor binding);GO:0017053(transcriptional repressor complex);GO:0003214(cardiac left ventricle morphogenesis);GO:0003222(ventricular trabecula myocardium morphogenesis);GO:0035912(dorsal aorta morphogenesis);GO:0003160(endocardium morphogenesis);GO:0003256(regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation);GO:0061419(positive regulation of transcription from RNA polymerase II promoter in response to hypoxia);GO:0002193(MAML1-RBP-Jkappa- ICN1 complex);GO:0036302(atrioventricular canal development);GO:0000150(recombinase activity);GO:0001077(transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0007221(positive regulation of transcription of Notch receptor target);GO:0060716(labyrinthine layer blood vessel development);GO:0072554(blood vessel lumenization);GO:0097101(blood vessel endothelial cell fate specification);GO:1901186(positive regulation of ERBB signaling pathway);GO:1901189(positive regulation of ephrin receptor signaling pathway);GO:0000979(RNA polymerase II core promoter sequence-specific DNA binding);GO:0001228(transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding);GO:0003682(chromatin binding);GO:0047485(protein N-terminus binding);GO:0001756(somitogenesis);GO:0001974(blood vessel remodeling);GO:0002437(inflammatory response to antigenic stimulus);GO:0003139(secondary heart field specification);GO:0003157(endocardium development);GO:0006959(humoral immune response);GO:0007507(heart development);GO:0008284(positive regulation of cell proliferation);GO:0008285(negative regulation of cell proliferation);GO:0009912(auditory receptor cell fate commitment);GO:0009957(epidermal cell fate specification);GO:0010468(regulation of gene expression);GO:0010628(positive regulation of gene expression);GO:0021983(pituitary gland development);GO:0030097(hemopoiesis);GO:0030182(neuron differentiation);GO:0030183(B cell differentiation);GO:0030216(keratinocyte differentiation);GO:0035019(somatic stem cell population maintenance);GO:0042127(regulation of cell proliferation);GO:0042742(defense response to bacterium);GO:0043011(myeloid dendritic cell differentiation);GO:0045165(cell fate commitment);GO:0045596(negative regulation of cell differentiation);GO:0048505(regulation of timing of cell differentiation);GO:0048733(sebaceous gland development);GO:0048820(hair follicle maturation);GO:0048844(artery morphogenesis);GO:0060486(Clara cell differentiation);GO:0060844(arterial endothelial cell fate commitment);GO:0072602(interleukin-4 secretion);GO:1901297(positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment);GO:0005667(transcription factor complex)","04330(Notch signaling pathway);04658(Th1 and Th2 cell differentiation);05203(Viral carcinogenesis);05169(Epstein-Barr virus infection);05165(Human papillomavirus infection)","NA","NA","recombination signal binding protein for immunoglobulin kappa J region [Source:HGNC Symbol;Acc:HGNC:5724]",0,{"v":0.008403,"d":"0.01"},"-inf","-inf",1,1,"down","no"]
[148118,0,"chr4","-",73113084,73153935,"ENST00000514252",19,3259,"ENSG00000132466","ANKRD17","GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0031965(nuclear membrane);GO:0002376(immune system process);GO:0045087(innate immune response);GO:0042742(defense response to bacterium);GO:0005515(protein binding);GO:0003682(chromatin binding);GO:0016032(viral process);GO:0043123(positive regulation of I-kappaB kinase/NF-kappaB signaling);GO:0000785(chromatin);GO:1900087(positive regulation of G1/S transition of mitotic cell cycle);GO:0045787(positive regulation of cell cycle);GO:0001955(blood vessel maturation);GO:0006275(regulation of DNA replication);GO:0051151(negative regulation of smooth muscle cell differentiation);GO:1900245(positive regulation of MDA-5 signaling pathway);GO:1900246(positive regulation of RIG-I signaling pathway)","NA","NA","NA","ankyrin repeat domain 17 [Source:HGNC Symbol;Acc:HGNC:23575]",{"v":0.384317,"d":"0.38"},{"v":0.003946,"d":"0.00"},{"v":97.3940699442473,"d":"97.39"},{"v":6.6057620281552,"d":"6.61"},1,1,"up","no"]
[73330,0,"chr16","+",56651899,56653204,"ENST00000334346",3,380,"ENSG00000169688","MT1B","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0008270(zinc ion binding);GO:0048471(perinuclear region of cytoplasm);GO:0045926(negative regulation of growth);GO:0071294(cellular response to zinc ion)","04978(Mineral absorption)","K14739","NA","metallothionein 1B [Source:HGNC Symbol;Acc:HGNC:7394]",0,0,1,0,1,1,"no","no"]
[90218,0,"chr18","-",2537530,2567613,"ENST00000573134",7,5190,"ENSG00000101574","METTL4","GO:0003676(nucleic acid binding);GO:0008168(methyltransferase activity);GO:0032259(methylation);GO:0006139(nucleobase-containing compound metabolic process);GO:0016740(transferase activity);GO:0005634(nucleus);GO:0009007(site-specific DNA-methyltransferase (adenine-specific) activity);GO:0032775(DNA methylation on adenine)","NA","NA","NA","methyltransferase like 4 [Source:HGNC Symbol;Acc:HGNC:24726]",{"v":0.02047,"d":"0.02"},{"v":0.019662,"d":"0.02"},{"v":1.04109449699929,"d":"1.04"},{"v":0.0581010236468569,"d":"0.06"},1,1,"up","no"]
[3725,0,"chr1","-",31727117,31764035,"ENST00000373655",33,5400,"ENSG00000121753","ADGRB2","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0004930(G-protein coupled receptor activity);GO:0007186(G-protein coupled receptor signaling pathway);GO:0004888(transmembrane signaling receptor activity);GO:0007166(cell surface receptor signaling pathway);GO:0016525(negative regulation of angiogenesis);GO:0005886(plasma membrane);GO:0004871(signal transducer activity);GO:0007165(signal transduction);GO:0007422(peripheral nervous system development);GO:0051965(positive regulation of synapse assembly)","NA","NA","NA","adhesion G protein-coupled receptor B2 [Source:HGNC Symbol;Acc:HGNC:944]",{"v":0.172223,"d":"0.17"},0,"inf","inf",1,1,"up","no"]
[10795,0,"chr1","+",151227267,151232641,"ENST00000481713",4,474,"MSTRG.947","PIP5K1A","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016607(nuclear speck);GO:0016020(membrane);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0005886(plasma membrane);GO:0042995(cell projection);GO:0008654(phospholipid biosynthetic process);GO:0005925(focal adhesion);GO:0016307(phosphatidylinositol phosphate kinase activity);GO:0046488(phosphatidylinositol metabolic process);GO:0046854(phosphatidylinositol phosphorylation);GO:0005515(protein binding);GO:0030027(lamellipodium);GO:0032587(ruffle membrane);GO:0090630(activation of GTPase activity);GO:0001726(ruffle);GO:0007165(signal transduction);GO:0048041(focal adhesion assembly);GO:0006909(phagocytosis);GO:0006661(phosphatidylinositol biosynthetic process);GO:0014066(regulation of phosphatidylinositol 3-kinase signaling);GO:0016477(cell migration);GO:0060326(cell chemotaxis);GO:0030216(keratinocyte differentiation);GO:0000285(1-phosphatidylinositol-3-phosphate 5-kinase activity);GO:0016308(1-phosphatidylinositol-4-phosphate 5-kinase activity);GO:0052810(1-phosphatidylinositol-5-kinase activity);GO:0052811(1-phosphatidylinositol-3-phosphate 4-kinase activity);GO:0052812(phosphatidylinositol-3,4-bisphosphate 5-kinase activity);GO:0031532(actin cytoskeleton reorganization);GO:0019900(kinase binding);GO:0005847(mRNA cleavage and polyadenylation specificity factor complex);GO:0072661(protein targeting to plasma membrane);GO:0097178(ruffle assembly);GO:0006650(glycerophospholipid metabolic process);GO:0010761(fibroblast migration)","00562(Inositol phosphate metabolism);04070(Phosphatidylinositol signaling system);04072(Phospholipase D signaling pathway);04144(Endocytosis);04810(Regulation of actin cytoskeleton);04666(Fc gamma R-mediated phagocytosis);05231(Choline metabolism in cancer)","NA","NA","phosphatidylinositol-4-phosphate 5-kinase type 1 alpha [Source:HGNC Symbol;Acc:HGNC:8994]",{"v":0.18203,"d":"0.18"},0,"inf","inf",1,1,"up","no"]
[90919,0,"chr18","-",12785481,12802153,"ENST00000591901",4,743,"MSTRG.7437","PTPN2","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0016787(hydrolase activity);GO:0004725(protein tyrosine phosphatase activity);GO:0016791(phosphatase activity);GO:0006470(protein dephosphorylation);GO:0016311(dephosphorylation);GO:0035335(peptidyl-tyrosine dephosphorylation);GO:0005783(endoplasmic reticulum);GO:0005886(plasma membrane);GO:0004721(phosphoprotein phosphatase activity);GO:0005515(protein binding);GO:0030218(erythrocyte differentiation);GO:0019901(protein kinase binding);GO:0008285(negative regulation of cell proliferation);GO:0050728(negative regulation of inflammatory response);GO:0019905(syntaxin binding);GO:0005178(integrin binding);GO:0030217(T cell differentiation);GO:0008286(insulin receptor signaling pathway);GO:0030971(receptor tyrosine kinase binding);GO:0060334(regulation of interferon-gamma-mediated signaling pathway);GO:0070373(negative regulation of ERK1 and ERK2 cascade);GO:0005793(endoplasmic reticulum-Golgi intermediate compartment);GO:0042532(negative regulation of tyrosine phosphorylation of STAT protein);GO:0046627(negative regulation of insulin receptor signaling pathway);GO:0042593(glucose homeostasis);GO:0050860(negative regulation of T cell receptor signaling pathway);GO:0045650(negative regulation of macrophage differentiation);GO:0030183(B cell differentiation);GO:0010804(negative regulation of tumor necrosis factor-mediated signaling pathway);GO:0050922(negative regulation of chemotaxis);GO:0010888(negative regulation of lipid storage);GO:0042059(negative regulation of epidermal growth factor receptor signaling pathway);GO:0045722(positive regulation of gluconeogenesis);GO:0060336(negative regulation of interferon-gamma-mediated signaling pathway);GO:0060339(negative regulation of type I interferon-mediated signaling pathway);GO:1902202(regulation of hepatocyte growth factor receptor signaling pathway);GO:1902206(negative regulation of interleukin-2-mediated signaling pathway);GO:1902227(negative regulation of macrophage colony-stimulating factor signaling pathway);GO:1902233(negative regulation of positive thymic T cell selection);GO:2000587(negative regulation of platelet-derived growth factor receptor-beta signaling pathway);GO:0004726(non-membrane spanning protein tyrosine phosphatase activity);GO:0097677(STAT family protein binding);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0061099(negative regulation of protein tyrosine kinase activity);GO:0070104(negative regulation of interleukin-6-mediated signaling pathway);GO:1902215(negative regulation of interleukin-4-mediated signaling pathway);GO:1902237(positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway);GO:1903899(positive regulation of PERK-mediated unfolded protein response);GO:0016021(integral component of membrane)","04630(Jak-STAT signaling pathway)","NA","NA","protein tyrosine phosphatase, non-receptor type 2 [Source:HGNC Symbol;Acc:HGNC:9650]",{"v":0.450161,"d":"0.45"},{"v":0.240394,"d":"0.24"},{"v":1.87259665382663,"d":"1.87"},{"v":0.905040185118027,"d":"0.91"},1,1,"up","no"]
[93695,0,"chr18","+",79400331,79527741,"ENST00000590313",9,1919,"MSTRG.7558","NFATC1","GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0005737(cytoplasm);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0005515(protein binding);GO:0016604(nuclear body);GO:0045893(positive regulation of transcription, DNA-templated);GO:0038095(Fc-epsilon receptor signaling pathway);GO:0005829(cytosol);GO:0000790(nuclear chromatin);GO:0006366(transcription from RNA polymerase II promoter);GO:0001085(RNA polymerase II transcription factor binding);GO:0000980(RNA polymerase II distal enhancer sequence-specific DNA binding);GO:0003705(transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding);GO:0035556(intracellular signal transduction);GO:0007223(Wnt signaling pathway, calcium modulating pathway);GO:0005528(FK506 binding);GO:0001205(transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding);GO:0048273(mitogen-activated protein kinase p38 binding);GO:0030178(negative regulation of Wnt signaling pathway);GO:0033173(calcineurin-NFAT signaling cascade);GO:0000977(RNA polymerase II regulatory region sequence-specific DNA binding);GO:0001225(RNA polymerase II transcription coactivator binding)","04010(MAPK signaling pathway);04310(Wnt signaling pathway);04024(cAMP signaling pathway);04022(cGMP - PKG signaling pathway);04218(Cellular senescence);04650(Natural killer cell mediated cytotoxicity);04660(T cell receptor signaling pathway);04658(Th1 and Th2 cell differentiation);04659(Th17 cell differentiation);04662(B cell receptor signaling pathway);04921(Oxytocin signaling pathway);04380(Osteoclast differentiation);05321(Inflammatiory bowel disease (IBD));04933(AGE-RAGE signaling pathway in diabetic complications);05166(HTLV-I infection);05161(Hepatitis B);05167(Kaposi's sarcoma-associated herpesvirus infection)","NA","NA","nuclear factor of activated T-cells 1 [Source:HGNC Symbol;Acc:HGNC:7775]",0,0,1,0,1,1,"no","no"]
[23619,0,"chr10","-",113834729,113854383,"ENST00000369305",10,4241,"MSTRG.1991","DCLRE1A","GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0001650(fibrillar center);GO:0051301(cell division);GO:0090305(nucleic acid phosphodiester bond hydrolysis);GO:0006281(DNA repair);GO:0006974(cellular response to DNA damage stimulus);GO:0007049(cell cycle);GO:0036297(interstrand cross-link repair);GO:0003684(damaged DNA binding);GO:0035312(5'-3' exodeoxyribonuclease activity);GO:0006303(double-strand break repair via nonhomologous end joining);GO:0031848(protection from non-homologous end joining at telomere);GO:0000784(nuclear chromosome, telomeric region)","NA","NA","NA","DNA cross-link repair 1A [Source:HGNC Symbol;Acc:HGNC:17660]",0,0,1,0,1,1,"no","no"]
[118236,0,"chr2","+",202924609,202925904,"ENST00000449849",1,1296,"MSTRG.9371","AC010900.1","NA","NA","NA","NA","NA",{"v":0.039902,"d":"0.04"},0,"inf","inf",1,1,"up","no"]
[56222,0,"chr14","-",68874859,68979076,"ENST00000538545",21,2813,"MSTRG.4498","ACTN1","GO:0051015(actin filament binding);GO:0003779(actin binding);GO:0051017(actin filament bundle assembly);GO:0051764(actin crosslink formation);GO:0005509(calcium ion binding);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0046872(metal ion binding);GO:0042803(protein homodimerization activity);GO:0005886(plasma membrane);GO:0005856(cytoskeleton);GO:0042995(cell projection);GO:0005515(protein binding);GO:1903506(regulation of nucleic acid-templated transcription);GO:0005615(extracellular space);GO:0030054(cell junction);GO:0030374(ligand-dependent nuclear receptor transcription coactivator activity);GO:0005925(focal adhesion);GO:0005576(extracellular region);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0005622(intracellular);GO:0001725(stress fiber);GO:0044325(ion channel binding);GO:0042981(regulation of apoptotic process);GO:0001726(ruffle);GO:0002576(platelet degranulation);GO:0048041(focal adhesion assembly);GO:0005178(integrin binding);GO:0031093(platelet alpha granule lumen);GO:0005911(cell-cell junction);GO:0005884(actin filament);GO:0030018(Z disc);GO:0007015(actin filament organization);GO:0017166(vinculin binding);GO:0003725(double-stranded RNA binding);GO:0031143(pseudopodium);GO:0030220(platelet formation);GO:0051271(negative regulation of cellular component movement);GO:0036344(platelet morphogenesis);GO:0051639(actin filament network formation);GO:0005903(brush border);GO:0005916(fascia adherens);GO:0030017(sarcomere)","04510(Focal adhesion);04520(Adherens junction);04530(Tight junction);04810(Regulation of actin cytoskeleton);04670(Leukocyte transendothelial migration);05203(Viral carcinogenesis);05322(Systemic lupus erythematosus);05146(Amoebiasis)","NA","NA","actinin alpha 1 [Source:HGNC Symbol;Acc:HGNC:163]",{"v":0.379677,"d":"0.38"},{"v":0.185925,"d":"0.19"},{"v":2.04209762000807,"d":"2.04"},{"v":1.03005183415657,"d":"1.03"},1,1,"up","no"]
[183084,0,"chr8","+",38386501,38408488,"ENST00000518883",11,2250,"ENSG00000165046","LETM2","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005743(mitochondrial inner membrane);GO:0005739(mitochondrion);GO:0043022(ribosome binding);GO:0006875(cellular metal ion homeostasis);GO:0003824(catalytic activity)","NA","NA","NA","leucine zipper and EF-hand containing transmembrane protein 2 [Source:HGNC Symbol;Acc:HGNC:14648]",{"v":0.120814,"d":"0.12"},{"v":0.072818,"d":"0.07"},{"v":1.65912274437639,"d":"1.66"},{"v":0.730420622974025,"d":"0.73"},1,1,"up","no"]
[124872,0,"chr20","+",57392230,57407860,"ENST00000371219",4,760,"MSTRG.9852","RBM38","GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0006397(mRNA processing);GO:0008380(RNA splicing);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0007049(cell cycle);GO:0030154(cell differentiation);GO:0043484(regulation of RNA splicing);GO:0003729(mRNA binding);GO:0010830(regulation of myotube differentiation)","NA","NA","NA","RNA binding motif protein 38 [Source:HGNC Symbol;Acc:HGNC:15818]",{"v":1.773823,"d":"1.77"},{"v":1.519945,"d":"1.52"},{"v":1.16703104388646,"d":"1.17"},{"v":0.222842938307775,"d":"0.22"},1,1,"up","no"]
[171414,0,"chr7","+",2652825,2658456,"ENST00000498454",4,587,"MSTRG.13457","TTYH3","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0006811(ion transport);GO:0005886(plasma membrane);GO:0005254(chloride channel activity);GO:0006821(chloride transport);GO:0034707(chloride channel complex);GO:1902476(chloride transmembrane transport);GO:0070062(extracellular exosome);GO:0005229(intracellular calcium activated chloride channel activity);GO:0034220(ion transmembrane transport)","NA","NA","NA","tweety family member 3 [Source:HGNC Symbol;Acc:HGNC:22222]",{"v":0.131785,"d":"0.13"},{"v":0.000433,"d":"0.00"},{"v":304.353348729792,"d":"304.35"},{"v":8.24960342931901,"d":"8.25"},1,1,"up","no"]
[58333,0,"chr14","-",97933062,97978056,"ENST00000556462",3,2098,"ENSG00000246223","LINC01550","NA","NA","NA","NA","long intergenic non-protein coding RNA 1550 [Source:HGNC Symbol;Acc:HGNC:20111]",{"v":0.323278,"d":"0.32"},{"v":0.112589,"d":"0.11"},{"v":2.87131069642683,"d":"2.87"},{"v":1.5217094489505,"d":"1.52"},1,1,"up","no"]
[186821,0,"chr8","+",123041968,123084269,"ENST00000520368",3,653,"MSTRG.14540","TBC1D31","GO:0005813(centrosome)","NA","NA","NA","TBC1 domain family member 31 [Source:HGNC Symbol;Acc:HGNC:30888]",{"v":0.058849,"d":"0.06"},0,"inf","inf",1,1,"up","no"]
[190403,0,"chr9","+",40121962,40122540,"ENST00000434123",1,579,"ENSG00000230804","C2orf27AP3","NA","NA","NA","NA","chromosome 2 open reading frame 27A pseudogene 3 [Source:HGNC Symbol;Acc:HGNC:50418]",0,0,1,0,1,1,"no","no"]
[202092,0,"chrY","+",23219475,23291352,"ENST00000382440",28,4119,"ENSG00000205944","DAZ2","GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0007275(multicellular organism development);GO:0030154(cell differentiation);GO:0007283(spermatogenesis);GO:0003730(mRNA 3'-UTR binding);GO:0007338(single fertilization);GO:0045948(positive regulation of translational initiation);GO:0008494(translation activator activity);GO:0070935(3'-UTR-mediated mRNA stabilization)","NA","NA","NA","deleted in azoospermia 2 [Source:HGNC Symbol;Acc:HGNC:15964]",0,0,1,0,1,1,"no","no"]
[128192,0,"chr22","+",16616170,16617114,"ENST00000438850",2,546,"MSTRG.10102","AP000365.1","NA","NA","NA","NA","NA",{"v":0.24741,"d":"0.25"},0,"inf","inf",1,1,"up","no"]
[2869,0,"chr1","-",25244072,25247446,"ENST00000431849",3,1954,"MSTRG.260","RSRP1","GO:0005515(protein binding)","NA","NA","NA","arginine and serine rich protein 1 [Source:HGNC Symbol;Acc:HGNC:25234]",{"v":1.456853,"d":"1.46"},{"v":0.343434,"d":"0.34"},{"v":4.24201738907621,"d":"4.24"},{"v":2.08475053484362,"d":"2.08"},1,1,"up","no"]
[90025,0,"chr17","+",82930458,82941433,"ENST00000575132",6,707,"ENSG00000141556","TBCD","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005886(plasma membrane);GO:0043547(positive regulation of GTPase activity);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0005096(GTPase activator activity);GO:0030054(cell junction);GO:0005813(centrosome);GO:0005815(microtubule organizing center);GO:0005923(bicellular tight junction);GO:0005912(adherens junction);GO:0006457(protein folding);GO:0048487(beta-tubulin binding);GO:0007021(tubulin complex assembly);GO:0007023(post-chaperonin tubulin folding pathway);GO:0016328(lateral plasma membrane);GO:0000278(mitotic cell cycle);GO:0070830(bicellular tight junction assembly);GO:0034333(adherens junction assembly);GO:0051087(chaperone binding);GO:0031115(negative regulation of microtubule polymerization);GO:0010812(negative regulation of cell-substrate adhesion);GO:0005874(microtubule);GO:0048667(cell morphogenesis involved in neuron differentiation)","NA","NA","NA","tubulin folding cofactor D [Source:HGNC Symbol;Acc:HGNC:11581]",{"v":0.229037,"d":"0.23"},{"v":0.230519,"d":"0.23"},{"v":0.993571028852285,"d":"0.99"},{"v":-0.00930498769420053,"d":"-0.01"},1,1,"down","no"]
[47966,0,"chr12","+",122980191,122982711,"ENST00000392435",5,1339,"MSTRG.3844","ARL6IP4","GO:0003723(RNA binding);GO:0006397(mRNA processing);GO:0008380(RNA splicing);GO:0005634(nucleus);GO:0016607(nuclear speck);GO:0005515(protein binding);GO:0005730(nucleolus)","NA","NA","NA","ADP ribosylation factor like GTPase 6 interacting protein 4 [Source:HGNC Symbol;Acc:HGNC:18076]",{"v":0.630235,"d":"0.63"},{"v":0.523471,"d":"0.52"},{"v":1.20395399172065,"d":"1.20"},{"v":0.26778026154554,"d":"0.27"},1,1,"up","no"]
[11493,0,"chr1","+",154983352,154991206,"ENST00000368433",4,2656,"MSTRG.1020","FLAD1","GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0003919(FMN adenylyltransferase activity);GO:0006747(FAD biosynthetic process);GO:0005737(cytoplasm);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0016740(transferase activity);GO:0003824(catalytic activity);GO:0008152(metabolic process);GO:0005739(mitochondrion);GO:0005515(protein binding);GO:0005759(mitochondrial matrix);GO:0016779(nucleotidyltransferase activity);GO:0055114(oxidation-reduction process);GO:0006771(riboflavin metabolic process)","00740(Riboflavin metabolism)","NA","NA","flavin adenine dinucleotide synthetase 1 [Source:HGNC Symbol;Acc:HGNC:24671]",{"v":0.222521,"d":"0.22"},{"v":0.038322,"d":"0.04"},{"v":5.80661238975001,"d":"5.81"},{"v":2.53769673267168,"d":"2.54"},1,1,"up","no"]
[168362,0,"chr6","+",109766729,109785744,"ENST00000415980",4,439,"ENSG00000112367","FIG4","GO:0016020(membrane);GO:0043231(intracellular membrane-bounded organelle);GO:0016787(hydrolase activity);GO:0016311(dephosphorylation);GO:0005515(protein binding);GO:0005811(lipid particle);GO:0036092(phosphatidylinositol-3-phosphate biosynthetic process);GO:0042578(phosphoric ester hydrolase activity);GO:0005768(endosome);GO:0010008(endosome membrane);GO:0006661(phosphatidylinositol biosynthetic process);GO:0000139(Golgi membrane);GO:0043813(phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity);GO:0031901(early endosome membrane);GO:0031902(late endosome membrane);GO:0004438(phosphatidylinositol-3-phosphatase activity);GO:0034593(phosphatidylinositol bisphosphate phosphatase activity);GO:0043812(phosphatidylinositol-4-phosphate phosphatase activity);GO:0007033(vacuole organization);GO:0007626(locomotory behavior);GO:0010976(positive regulation of neuron projection development);GO:0031642(negative regulation of myelination);GO:0032288(myelin assembly);GO:0043473(pigmentation);GO:0046488(phosphatidylinositol metabolic process);GO:0048666(neuron development);GO:0005783(endoplasmic reticulum);GO:0005794(Golgi apparatus);GO:0055037(recycling endosome);GO:0016021(integral component of membrane)","NA","NA","NA","FIG4 phosphoinositide 5-phosphatase [Source:HGNC Symbol;Acc:HGNC:16873]",0,{"v":0.203687,"d":"0.20"},"-inf","-inf",1,1,"down","no"]
[83915,0,"chr17","-",43221531,43224463,"ENST00000594857",3,689,"MSTRG.6870","LINC00854","NA","NA","NA","NA","long intergenic non-protein coding RNA 854 [Source:HGNC Symbol;Acc:HGNC:43658]",0,{"v":0.150349,"d":"0.15"},"-inf","-inf",1,1,"down","no"]
[86086,0,"chr17","+",58337203,58352491,"ENST00000583826",4,1004,"MSTRG.7060","TSPOAP1-AS1","NA","NA","NA","NA","TSPOAP1 antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:44148]",0,0,1,0,1,1,"no","no"]
[84623,0,"chr17","-",46259551,46260606,"ENST00000571422",1,1056,"ENSG00000262539","AC005829.2","NA","NA","NA","NA","NA",{"v":0.075204,"d":"0.08"},{"v":0.070773,"d":"0.07"},{"v":1.06260862193209,"d":"1.06"},{"v":0.0876103238978437,"d":"0.09"},1,1,"up","no"]
[201678,0,"chrY","-",9463852,9465974,"ENST00000423213",8,766,"ENSG00000225516","FAM197Y5","NA","NA","NA","NA","family with sequence similarity 197 Y-linked member 5 [Source:HGNC Symbol;Acc:HGNC:37467]",0,0,1,0,1,1,"no","no"]
[195246,0,"chr9","+",137800443,137815951,"ENST00000488242",7,789,"MSTRG.15148","EHMT1","GO:0005634(nucleus);GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0005654(nucleoplasm);GO:0008168(methyltransferase activity);GO:0016740(transferase activity);GO:0032259(methylation);GO:0016569(covalent chromatin modification);GO:0005694(chromosome);GO:0005515(protein binding);GO:0016604(nuclear body);GO:0018024(histone-lysine N-methyltransferase activity);GO:0018026(peptidyl-lysine monomethylation);GO:0018027(peptidyl-lysine dimethylation);GO:0034968(histone lysine methylation);GO:0016279(protein-lysine N-methyltransferase activity);GO:0006325(chromatin organization);GO:0045892(negative regulation of transcription, DNA-templated);GO:1901796(regulation of signal transduction by p53 class mediator);GO:0009790(embryo development);GO:0002039(p53 binding);GO:0046974(histone methyltransferase activity (H3-K9 specific));GO:0046976(histone methyltransferase activity (H3-K27 specific));GO:0070734(histone H3-K27 methylation);GO:0016571(histone methylation);GO:0006306(DNA methylation);GO:0051567(histone H3-K9 methylation);GO:0070742(C2H2 zinc finger domain binding);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0060992(response to fungicide);GO:0016020(membrane);GO:0016021(integral component of membrane)","00310(Lysine degradation);04211(Longevity regulating pathway - mammal)","NA","NA","euchromatic histone lysine methyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:24650]",0,{"v":0.058872,"d":"0.06"},"-inf","-inf",1,1,"down","no"]
[28531,0,"chr11","+",46375024,46377350,"ENST00000529698",7,792,"MSTRG.2358","DGKZ","GO:0005737(cytoplasm);GO:0005634(nucleus);GO:0016607(nuclear speck);GO:0016020(membrane);GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0035556(intracellular signal transduction);GO:0008152(metabolic process);GO:0003951(NAD+ kinase activity);GO:0005886(plasma membrane);GO:0004143(diacylglycerol kinase activity);GO:0007205(protein kinase C-activating G-protein coupled receptor signaling pathway);GO:0005515(protein binding);GO:0030027(lamellipodium);GO:0030168(platelet activation);GO:0016477(cell migration);GO:0046339(diacylglycerol metabolic process);GO:0046834(lipid phosphorylation);GO:0046486(glycerolipid metabolic process);GO:0005622(intracellular)","00561(Glycerolipid metabolism);00564(Glycerophospholipid metabolism);04070(Phosphatidylinositol signaling system);04072(Phospholipase D signaling pathway);05231(Choline metabolism in cancer)","NA","NA","diacylglycerol kinase zeta [Source:HGNC Symbol;Acc:HGNC:2857]",0,0,1,0,1,1,"no","no"]
[3818,0,"chr1","+",32209096,32216192,"ENST00000487056",7,1863,"MSTRG.366","DCDC2B","GO:0005622(intracellular);GO:0035556(intracellular signal transduction);GO:0005515(protein binding)","NA","NA","NA","doublecortin domain containing 2B [Source:HGNC Symbol;Acc:HGNC:32576]",{"v":0.012777,"d":"0.01"},{"v":0.040252,"d":"0.04"},{"v":0.317425221107026,"d":"0.32"},{"v":-1.65551133243434,"d":"-1.66"},1,1,"down","no"]
[106231,0,"chr19","-",57350848,57352012,"ENST00000597973",2,1045,"ENSG00000268678","AC005261.3","NA","NA","NA","NA","NA",{"v":0.197794,"d":"0.20"},{"v":0.079743,"d":"0.08"},{"v":2.48039326335854,"d":"2.48"},{"v":1.31056887630477,"d":"1.31"},1,1,"up","no"]
[67860,0,"chr16","-",1358900,1361405,"ENST00000569831",2,435,"MSTRG.5497","AL031709.1","NA","NA","NA","NA","NA",{"v":0.13633,"d":"0.14"},{"v":0.035821,"d":"0.04"},{"v":3.80586806621814,"d":"3.81"},{"v":1.92822555017948,"d":"1.93"},1,1,"up","no"]
[115263,0,"chr2","-",151277255,151289863,"ENST00000491771",3,2094,"MSTRG.9166","NMI","GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0006366(transcription from RNA polymerase II promoter);GO:0005515(protein binding);GO:1903506(regulation of nucleic acid-templated transcription);GO:0003712(transcription cofactor activity);GO:0042802(identical protein binding);GO:0006954(inflammatory response);GO:0007259(JAK-STAT cascade);GO:0032480(negative regulation of type I interferon production);GO:0045355(negative regulation of interferon-alpha biosynthetic process);GO:0045358(negative regulation of interferon-beta biosynthetic process);GO:0045824(negative regulation of innate immune response);GO:0060333(interferon-gamma-mediated signaling pathway);GO:1902524(positive regulation of protein K48-linked ubiquitination)","NA","NA","NA","N-myc and STAT interactor [Source:HGNC Symbol;Acc:HGNC:7854]",{"v":0.109747,"d":"0.11"},{"v":0.288362,"d":"0.29"},{"v":0.380587594759365,"d":"0.38"},{"v":-1.39369955710837,"d":"-1.39"},1,1,"down","no"]
[103821,0,"chr19","+",49340595,49343335,"ENST00000600121",2,319,"MSTRG.8307","CD37","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005515(protein binding);GO:0005887(integral component of plasma membrane);GO:0070062(extracellular exosome);GO:0007166(cell surface receptor signaling pathway);GO:0001772(immunological synapse)","04640(Hematopoietic cell lineage)","NA","NA","CD37 molecule [Source:HGNC Symbol;Acc:HGNC:1666]",0,0,1,0,1,1,"no","no"]
[4139,0,"chr1","-",35018513,35031690,"ENST00000373333",5,1473,"MSTRG.404","ZMYM6","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0005737(cytoplasm);GO:0000981(RNA polymerase II transcription factor activity, sequence-specific DNA binding);GO:0007010(cytoskeleton organization);GO:0022604(regulation of cell morphogenesis);GO:0005654(nucleoplasm);GO:0003677(DNA binding);GO:0007275(multicellular organism development)","NA","NA","NA","zinc finger MYM-type containing 6 [Source:HGNC Symbol;Acc:HGNC:13050]",{"v":0.120058,"d":"0.12"},{"v":0.08219,"d":"0.08"},{"v":1.46073731597518,"d":"1.46"},{"v":0.546696761979063,"d":"0.55"},1,1,"up","no"]
[23209,0,"chr10","-",103099926,103140192,"ENST00000487810",8,669,"MSTRG.1950","NT5C2","GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0016787(hydrolase activity);GO:0016311(dephosphorylation);GO:0005515(protein binding);GO:0003824(catalytic activity);GO:0008152(metabolic process);GO:0016310(phosphorylation);GO:0008253(5'-nucleotidase activity);GO:0009117(nucleotide metabolic process);GO:0005829(cytosol);GO:0006195(purine nucleotide catabolic process);GO:0017144(drug metabolic process);GO:0046040(IMP metabolic process);GO:0050146(nucleoside phosphotransferase activity);GO:0046085(adenosine metabolic process)","00230(Purine metabolism);00240(Pyrimidine metabolism);00760(Nicotinate and nicotinamide metabolism)","NA","NA","5'-nucleotidase, cytosolic II [Source:HGNC Symbol;Acc:HGNC:8022]",{"v":0.000335,"d":"0.00"},{"v":1.94E-4,"d":"0.00"},{"v":1.72680412371134,"d":"1.73"},{"v":0.788104443158007,"d":"0.79"},1,1,"up","no"]
[78864,0,"chr17","+",7558759,7560838,"ENST00000625791",5,955,"MSTRG.6423","TNFSF13","GO:0016020(membrane);GO:0006955(immune response);GO:0005125(cytokine activity);GO:0005615(extracellular space);GO:0005164(tumor necrosis factor receptor binding);GO:0005737(cytoplasm);GO:0005576(extracellular region);GO:0002376(immune system process);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0033209(tumor necrosis factor-mediated signaling pathway);GO:0043488(regulation of mRNA stability);GO:0007165(signal transduction);GO:0005102(receptor binding);GO:0008284(positive regulation of cell proliferation);GO:0048298(positive regulation of isotype switching to IgA isotypes);GO:0016021(integral component of membrane)","04060(Cytokine-cytokine receptor interaction);04672(Intestinal immune network for IgA production);05323(Rheumatoid arthritis)","K05475","NA","TNF superfamily member 13 [Source:HGNC Symbol;Acc:HGNC:11928]",{"v":0.119333,"d":"0.12"},{"v":0.344002,"d":"0.34"},{"v":0.346896238975355,"d":"0.35"},{"v":-1.52742389577652,"d":"-1.53"},1,1,"down","no"]
[61923,0,"chr15","+",44288731,44348918,"ENST00000557945",6,1386,"MSTRG.5037","CASC4","GO:0005794(Golgi apparatus);GO:0016020(membrane);GO:0016021(integral component of membrane)","NA","NA","NA","cancer susceptibility 4 [Source:HGNC Symbol;Acc:HGNC:24892]",{"v":0.085358,"d":"0.09"},{"v":0.029038,"d":"0.03"},{"v":2.93952751566912,"d":"2.94"},{"v":1.55558428241517,"d":"1.56"},1,1,"up","no"]
[25583,0,"chr11","-",3549745,3550519,"ENST00000426436",1,775,"ENSG00000237226","AC127526.2","NA","NA","NA","NA","NA",0,0,1,0,1,1,"no","no"]
[81753,0,"chr17","-",30897336,30899115,"ENST00000579183",2,633,"ENSG00000172171","TEFM","GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0005739(mitochondrion);GO:0030529(intracellular ribonucleoprotein complex);GO:0006259(DNA metabolic process);GO:0005759(mitochondrial matrix);GO:0005515(protein binding);GO:0006390(transcription from mitochondrial promoter);GO:0042645(mitochondrial nucleoid);GO:0006119(oxidative phosphorylation);GO:0030337(DNA polymerase processivity factor activity)","NA","NA","NA","transcription elongation factor, mitochondrial [Source:HGNC Symbol;Acc:HGNC:26223]",{"v":0.096992,"d":"0.10"},{"v":0.160796,"d":"0.16"},{"v":0.603199084554342,"d":"0.60"},{"v":-0.729293855786609,"d":"-0.73"},1,1,"down","no"]
[144370,0,"chr3","+",195683460,195686340,"ENST00000627767",2,929,"ENSG00000242086","LINC00969","NA","NA","NA","NA","long intergenic non-protein coding RNA 969 [Source:HGNC Symbol;Acc:HGNC:48729]",{"v":0.052637,"d":"0.05"},0,"inf","inf",1,1,"up","no"]
[124947,0,"chr20","+",58438977,58445552,"ENST00000476395",2,3583,"MSTRG.9854","VAPB","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005794(Golgi apparatus);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0042803(protein homodimerization activity);GO:0005515(protein binding);GO:0008017(microtubule binding);GO:0030968(endoplasmic reticulum unfolded protein response);GO:0006874(cellular calcium ion homeostasis);GO:0000139(Golgi membrane);GO:0006986(response to unfolded protein);GO:0045296(cadherin binding);GO:0016032(viral process);GO:0006888(ER to Golgi vesicle-mediated transport);GO:0019899(enzyme binding);GO:0046982(protein heterodimerization activity);GO:0030148(sphingolipid biosynthetic process);GO:0007029(endoplasmic reticulum organization);GO:0048487(beta-tubulin binding);GO:0045070(positive regulation of viral genome replication);GO:0006987(activation of signaling protein activity involved in unfolded protein response);GO:0033149(FFAT motif binding);GO:0019048(modulation by virus of host morphology or physiology);GO:0090114(COPII-coated vesicle budding)","04979(Cholesterol metabolism)","NA","NA","VAMP associated protein B and C [Source:HGNC Symbol;Acc:HGNC:12649]",{"v":0.133519,"d":"0.13"},{"v":0.093642,"d":"0.09"},{"v":1.42584524038359,"d":"1.43"},{"v":0.51181740180461,"d":"0.51"},1,1,"up","no"]
[54663,0,"chr14","-",45246821,45253177,"ENST00000451174",3,808,"MSTRG.4363","MIS18BP1","GO:0005634(nucleus);GO:0003677(DNA binding);GO:0051301(cell division);GO:0005694(chromosome);GO:0005515(protein binding);GO:0007049(cell cycle);GO:0000775(chromosome, centromeric region);GO:0005654(nucleoplasm);GO:0034080(CENP-A containing nucleosome assembly);GO:0000778(condensed nuclear chromosome kinetochore)","NA","NA","NA","MIS18 binding protein 1 [Source:HGNC Symbol;Acc:HGNC:20190]",{"v":0.477654,"d":"0.48"},{"v":0.315831,"d":"0.32"},{"v":1.51237212306582,"d":"1.51"},{"v":0.596813162077722,"d":"0.60"},1,1,"up","no"]
[55696,0,"chr14","+",61525090,61529205,"ENST00000555110",2,268,"MSTRG.4455","PRKCH","GO:0004672(protein kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0005622(intracellular);GO:0046872(metal ion binding);GO:0035556(intracellular signal transduction);GO:0005737(cytoplasm);GO:0000166(nucleotide binding);GO:0004674(protein serine/threonine kinase activity);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0004697(protein kinase C activity);GO:0030154(cell differentiation);GO:0070062(extracellular exosome);GO:0018105(peptidyl-serine phosphorylation);GO:2000810(regulation of bicellular tight junction assembly);GO:0007165(signal transduction);GO:0019899(enzyme binding);GO:0051092(positive regulation of NF-kappaB transcription factor activity);GO:0030168(platelet activation);GO:0034351(negative regulation of glial cell apoptotic process);GO:0010744(positive regulation of macrophage derived foam cell differentiation);GO:0045618(positive regulation of keratinocyte differentiation);GO:1903078(positive regulation of protein localization to plasma membrane);GO:0050861(positive regulation of B cell receptor signaling pathway);GO:0004699(calcium-independent protein kinase C activity);GO:0017160(Ral GTPase binding);GO:0060252(positive regulation of glial cell proliferation);GO:0070528(protein kinase C signaling);GO:0005911(cell-cell junction);GO:0016020(membrane)","04270(Vascular smooth muscle contraction);04750(Inflammatory mediator regulation of TRP channels)","NA","NA","protein kinase C eta [Source:HGNC Symbol;Acc:HGNC:9403]",{"v":6.02E-4,"d":"0.00"},0,"inf","inf",1,1,"up","no"]
[19288,0,"chr10","+",27504377,27538489,"ENST00000465772",6,985,"MSTRG.1627","RAB18","GO:0006810(transport);GO:0016020(membrane);GO:0015031(protein transport);GO:0005525(GTP binding);GO:0000166(nucleotide binding);GO:0003924(GTPase activity);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0007275(multicellular organism development);GO:0005789(endoplasmic reticulum membrane);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0001654(eye development);GO:0061024(membrane organization);GO:0005794(Golgi apparatus);GO:0043312(neutrophil degranulation);GO:0019003(GDP binding);GO:0030667(secretory granule membrane);GO:0007420(brain development);GO:0005622(intracellular);GO:0071786(endoplasmic reticulum tubular network organization);GO:0007264(small GTPase mediated signal transduction);GO:0071782(endoplasmic reticulum tubular network);GO:0034389(lipid particle organization);GO:1902593(single-organism nuclear import)","NA","NA","NA","RAB18, member RAS oncogene family [Source:HGNC Symbol;Acc:HGNC:14244]",{"v":0.503104,"d":"0.50"},{"v":0.566917,"d":"0.57"},{"v":0.887438549205616,"d":"0.89"},{"v":-0.172280871524315,"d":"-0.17"},1,1,"down","no"]
[126799,0,"chr21","+",33811204,33814507,"ENST00000465143",2,614,"MSTRG.10040","ITSN1","GO:0016020(membrane);GO:0046872(metal ion binding);GO:0035556(intracellular signal transduction);GO:0005509(calcium ion binding);GO:0005886(plasma membrane);GO:0005089(Rho guanyl-nucleotide exchange factor activity);GO:0035023(regulation of Rho protein signal transduction);GO:0043547(positive regulation of GTPase activity);GO:0042995(cell projection);GO:0005515(protein binding);GO:0030054(cell junction);GO:0045202(synapse);GO:0005905(clathrin-coated pit);GO:0005085(guanyl-nucleotide exchange factor activity);GO:0005829(cytosol);GO:0006897(endocytosis);GO:0030027(lamellipodium);GO:0051056(regulation of small GTPase mediated signal transduction);GO:0061024(membrane organization);GO:0012505(endomembrane system);GO:0016032(viral process);GO:0043005(neuron projection);GO:0070064(proline-rich region binding);GO:0048013(ephrin receptor signaling pathway);GO:0043065(positive regulation of apoptotic process);GO:0032947(protein complex scaffold);GO:0042327(positive regulation of phosphorylation);GO:0048488(synaptic vesicle endocytosis);GO:0019209(kinase activator activity);GO:0007264(small GTPase mediated signal transduction);GO:0043524(negative regulation of neuron apoptotic process);GO:0051897(positive regulation of protein kinase B signaling);GO:0030139(endocytic vesicle);GO:0005524(ATP binding);GO:0006750(glutathione biosynthetic process);GO:0004363(glutathione synthase activity);GO:0016021(integral component of membrane)","NA","NA","NA","intersectin 1 [Source:HGNC Symbol;Acc:HGNC:6183]",{"v":0.022943,"d":"0.02"},0,"inf","inf",1,1,"up","no"]
[104805,0,"chr19","+",51949162,51981367,"ENST00000595010",3,698,"ENSG00000269235","ZNF350-AS1","NA","NA","NA","NA","ZNF350 antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:48598]",0,{"v":0.072428,"d":"0.07"},"-inf","-inf",1,1,"down","no"]
[75660,0,"chr16","-",74664335,74666832,"ENST00000572840",2,458,"ENSG00000168411","RFWD3","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0005654(nucleoplasm);GO:0016740(transferase activity);GO:0016567(protein ubiquitination);GO:0005515(protein binding);GO:0006281(DNA repair);GO:0006974(cellular response to DNA damage stimulus);GO:0031297(replication fork processing);GO:0004842(ubiquitin-protein transferase activity);GO:0016605(PML body);GO:0000724(double-strand break repair via homologous recombination);GO:0002039(p53 binding);GO:0035861(site of double-strand break);GO:0010212(response to ionizing radiation);GO:0036297(interstrand cross-link repair);GO:0031571(mitotic G1 DNA damage checkpoint);GO:2000001(regulation of DNA damage checkpoint);GO:0097371(MDM2/MDM4 family protein binding);GO:0090734(site of DNA damage)","NA","NA","NA","ring finger and WD repeat domain 3 [Source:HGNC Symbol;Acc:HGNC:25539]",{"v":0.091502,"d":"0.09"},{"v":0.075937,"d":"0.08"},{"v":1.20497254302909,"d":"1.20"},{"v":0.26900027302198,"d":"0.27"},1,1,"up","no"]
[99338,0,"chr19","+",23116975,23147219,"ENST00000597761",4,2374,"ENSG00000183850","ZNF730","GO:0003676(nucleic acid binding);GO:0006355(regulation of transcription, DNA-templated);GO:0005622(intracellular);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding)","NA","NA","NA","zinc finger protein 730 [Source:HGNC Symbol;Acc:HGNC:32470]",0,0,1,0,1,1,"no","no"]
[71057,0,"chr16","+",27214638,27216134,"ENST00000568792",2,561,"ENSG00000155666","KDM8","GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0016569(covalent chromatin modification);GO:0007049(cell cycle);GO:0051213(dioxygenase activity);GO:0045893(positive regulation of transcription, DNA-templated);GO:0003682(chromatin binding);GO:0032452(histone demethylase activity);GO:0000086(G2/M transition of mitotic cell cycle);GO:0051864(histone demethylase activity (H3-K36 specific));GO:0070544(histone H3-K36 demethylation)","NA","NA","NA","lysine demethylase 8 [Source:HGNC Symbol;Acc:HGNC:25840]",{"v":0.090017,"d":"0.09"},0,"inf","inf",1,1,"up","no"]
[173932,0,"chr7","-",47987156,48029048,"ENST00000449896",11,1456,"ENSG00000164744","SUN3","GO:0005634(nucleus);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005637(nuclear inner membrane);GO:0005635(nuclear envelope);GO:0043495(protein anchor);GO:0006998(nuclear envelope organization);GO:0090286(cytoskeletal anchoring at nuclear membrane);GO:0034993(LINC complex)","NA","NA","NA","Sad1 and UNC84 domain containing 3 [Source:HGNC Symbol;Acc:HGNC:22429]",0,0,1,0,1,1,"no","no"]
[125725,0,"chr21","+",5582228,5592004,"ENST00000624444",2,7628,"ENSG00000274333","CU633967.1","NA","NA","NA","NA","NA",{"v":0.011827,"d":"0.01"},{"v":0.126734,"d":"0.13"},{"v":0.0933214449161235,"d":"0.09"},{"v":-3.42164754472021,"d":"-3.42"},1,1,"down","no"]
[25971,0,"chr11","-",6026671,6027741,"ENST00000641938",1,1071,"ENSG00000180934","OR56A1","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0004930(G-protein coupled receptor activity);GO:0007186(G-protein coupled receptor signaling pathway);GO:0005886(plasma membrane);GO:0004871(signal transducer activity);GO:0007165(signal transduction);GO:0004984(olfactory receptor activity);GO:0007608(sensory perception of smell);GO:0050896(response to stimulus);GO:0050911(detection of chemical stimulus involved in sensory perception of smell);GO:0005887(integral component of plasma membrane);GO:0030672(synaptic vesicle membrane);GO:0042493(response to drug);GO:0060158(phospholipase C-activating dopamine receptor signaling pathway);GO:0001591(dopamine neurotransmitter receptor activity, coupled via Gi/Go);GO:0035240(dopamine binding);GO:0001963(synaptic transmission, dopaminergic);GO:0007194(negative regulation of adenylate cyclase activity);GO:0007195(adenylate cyclase-inhibiting dopamine receptor signaling pathway);GO:0009636(response to toxic substance);GO:0014059(regulation of dopamine secretion);GO:0043266(regulation of potassium ion transport);GO:0048148(behavioral response to cocaine);GO:0048149(behavioral response to ethanol);GO:0051481(negative regulation of cytosolic calcium ion concentration);GO:0051967(negative regulation of synaptic transmission, glutamatergic);GO:1901386(negative regulation of voltage-gated calcium channel activity)","04740(Olfactory transduction)","NA","NA","olfactory receptor family 56 subfamily A member 1 [Source:HGNC Symbol;Acc:HGNC:14781]",0,0,1,0,1,1,"no","no"]
[32965,0,"chr11","+",73787906,73844981,"ENST00000535277",6,598,"MSTRG.2682","MRPL48","GO:0030529(intracellular ribonucleoprotein complex);GO:0005840(ribosome);GO:0005739(mitochondrion);GO:0005761(mitochondrial ribosome);GO:0005515(protein binding);GO:0005743(mitochondrial inner membrane);GO:0070125(mitochondrial translational elongation);GO:0070126(mitochondrial translational termination);GO:0005762(mitochondrial large ribosomal subunit)","NA","NA","NA","mitochondrial ribosomal protein L48 [Source:HGNC Symbol;Acc:HGNC:16653]",{"v":0.200808,"d":"0.20"},{"v":0.360035,"d":"0.36"},{"v":0.557745774716347,"d":"0.56"},{"v":-0.842320415721151,"d":"-0.84"},1,1,"down","no"]
[50661,0,"chr13","-",52842889,52848640,"ENST00000377942",3,5088,"ENSG00000136099","PCDH8","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005509(calcium ion binding);GO:0007155(cell adhesion);GO:0007156(homophilic cell adhesion via plasma membrane adhesion molecules);GO:0005886(plasma membrane);GO:0042995(cell projection);GO:0030054(cell junction);GO:0045202(synapse);GO:0045211(postsynaptic membrane);GO:0030425(dendrite);GO:0007399(nervous system development);GO:0005887(integral component of plasma membrane);GO:0007267(cell-cell signaling);GO:0042734(presynaptic membrane);GO:0001756(somitogenesis);GO:0007268(chemical synaptic transmission);GO:0016331(morphogenesis of embryonic epithelium)","NA","NA","NA","protocadherin 8 [Source:HGNC Symbol;Acc:HGNC:8660]",0,0,1,0,1,1,"no","no"]
[77497,0,"chr17","-",1535507,1562780,"ENST00000576010",8,573,"MSTRG.6285","PITPNA","GO:0006810(transport);GO:0005737(cytoplasm);GO:0005622(intracellular);GO:0008289(lipid binding);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0007601(visual perception);GO:0035722(interleukin-12-mediated signaling pathway);GO:0008526(phosphatidylinositol transporter activity);GO:0031210(phosphatidylcholine binding);GO:0035091(phosphatidylinositol binding);GO:0006629(lipid metabolic process);GO:0015914(phospholipid transport);GO:0008525(phosphatidylcholine transporter activity);GO:1901611(phosphatidylglycerol binding);GO:0007409(axonogenesis);GO:0043209(myelin sheath)","NA","NA","NA","phosphatidylinositol transfer protein alpha [Source:HGNC Symbol;Acc:HGNC:9001]",0,{"v":0.450014,"d":"0.45"},"-inf","-inf",1,1,"down","no"]
[24012,0,"chr10","-",121957141,121975216,"ENST00000489266",11,2399,"MSTRG.2022","NSMCE4A","GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005694(chromosome);GO:0006281(DNA repair);GO:0005515(protein binding);GO:0006310(DNA recombination);GO:0006974(cellular response to DNA damage stimulus);GO:0016604(nuclear body);GO:0030915(Smc5-Smc6 complex);GO:0000781(chromosome, telomeric region);GO:2001022(positive regulation of response to DNA damage stimulus)","NA","NA","NA","NSE4 homolog A, SMC5-SMC6 complex component [Source:HGNC Symbol;Acc:HGNC:25935]",{"v":0.193725,"d":"0.19"},{"v":0.358718,"d":"0.36"},{"v":0.540048171544221,"d":"0.54"},{"v":-0.888839995484669,"d":"-0.89"},1,1,"down","no"]
[32085,0,"chr11","+",67608226,67609586,"ENST00000528314",3,559,"MSTRG.2621","NDUFV1","GO:0016020(membrane);GO:0046872(metal ion binding);GO:0005829(cytosol);GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0005739(mitochondrion);GO:0005743(mitochondrial inner membrane);GO:0051287(NAD binding);GO:0070469(respiratory chain);GO:0051536(iron-sulfur cluster binding);GO:0051539(4 iron, 4 sulfur cluster binding);GO:0008137(NADH dehydrogenase (ubiquinone) activity);GO:0016651(oxidoreductase activity, acting on NAD(P)H);GO:0010181(FMN binding);GO:0003954(NADH dehydrogenase activity);GO:0006120(mitochondrial electron transport, NADH to ubiquinone);GO:0032981(mitochondrial respiratory chain complex I assembly);GO:0005747(mitochondrial respiratory chain complex I);GO:0042775(mitochondrial ATP synthesis coupled electron transport)","00190(Oxidative phosphorylation);04723(Retrograde endocannabinoid signaling);05010(Alzheimer's disease);05012(Parkinson's disease);05016(Huntington's disease);04932(Non-alcoholic fatty liver disease (NAFLD))","NA","NA","NADH:ubiquinone oxidoreductase core subunit V1 [Source:HGNC Symbol;Acc:HGNC:7716]",{"v":1.255545,"d":"1.26"},{"v":0.796266,"d":"0.80"},{"v":1.57679092162669,"d":"1.58"},{"v":0.656991375201638,"d":"0.66"},1,1,"up","no"]
[163096,0,"chr6","-",17763693,17987569,"ENST00000259711",39,5941,"ENSG00000137177","KIF13A","GO:0006810(transport);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0015031(protein transport);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0005794(Golgi apparatus);GO:0051301(cell division);GO:0003777(microtubule motor activity);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0007049(cell cycle);GO:0008017(microtubule binding);GO:0000139(Golgi membrane);GO:0005874(microtubule);GO:0007018(microtubule-based movement);GO:0006886(intracellular protein transport);GO:0005813(centrosome);GO:0005815(microtubule organizing center);GO:0030496(midbody);GO:0072383(plus-end-directed vesicle transport along microtubule);GO:0005768(endosome);GO:0008333(endosome to lysosome transport);GO:0030705(cytoskeleton-dependent intracellular transport);GO:0016887(ATPase activity);GO:0010008(endosome membrane);GO:0005871(kinesin complex);GO:0032438(melanosome organization);GO:0000910(cytokinesis);GO:0032588(trans-Golgi network membrane);GO:0035459(cargo loading into vesicle);GO:0043001(Golgi to plasma membrane protein transport);GO:0005622(intracellular);GO:0005623(cell);GO:0003774(motor activity)","NA","NA","NA","kinesin family member 13A [Source:HGNC Symbol;Acc:HGNC:14566]",0,0,1,0,1,1,"no","no"]
[110901,0,"chr2","+",71068647,71078613,"ENST00000450272",10,1833,"MSTRG.8814","NAGK","GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0005515(protein binding);GO:0046835(carbohydrate phosphorylation);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0006048(UDP-N-acetylglucosamine biosynthetic process);GO:0006044(N-acetylglucosamine metabolic process);GO:0019262(N-acetylneuraminate catabolic process);GO:0045127(N-acetylglucosamine kinase activity);GO:0006051(N-acetylmannosamine metabolic process)","00520(Amino sugar and nucleotide sugar metabolism)","NA","NA","N-acetylglucosamine kinase [Source:HGNC Symbol;Acc:HGNC:17174]",{"v":0.198809,"d":"0.20"},{"v":0.656468,"d":"0.66"},{"v":0.302846444914299,"d":"0.30"},{"v":-1.72334161905771,"d":"-1.72"},1,1,"down","no"]
[142960,0,"chr3","-",179588831,179604649,"ENST00000392659",6,673,"MSTRG.11358","MRPL47","GO:0005739(mitochondrion);GO:0030529(intracellular ribonucleoprotein complex);GO:0003735(structural constituent of ribosome);GO:0006412(translation);GO:0005840(ribosome);GO:0005761(mitochondrial ribosome);GO:0003674(molecular_function);GO:0008150(biological_process);GO:0005575(cellular_component);GO:0032543(mitochondrial translation);GO:0005743(mitochondrial inner membrane);GO:0070125(mitochondrial translational elongation);GO:0070126(mitochondrial translational termination);GO:0005762(mitochondrial large ribosomal subunit)","NA","NA","NA","mitochondrial ribosomal protein L47 [Source:HGNC Symbol;Acc:HGNC:16652]",{"v":0.624256,"d":"0.62"},0,"inf","inf",1,1,"up","no"]
[13976,0,"chr1","+",179294320,179341310,"ENST00000426956",7,870,"MSTRG.1231","SOAT1","GO:0042632(cholesterol homeostasis);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005783(endoplasmic reticulum);GO:0016740(transferase activity);GO:0016746(transferase activity, transferring acyl groups);GO:0006629(lipid metabolic process);GO:0005789(endoplasmic reticulum membrane);GO:0008202(steroid metabolic process);GO:0005515(protein binding);GO:0008203(cholesterol metabolic process);GO:0008374(O-acyltransferase activity);GO:0000062(fatty-acyl-CoA binding);GO:0033344(cholesterol efflux);GO:0034383(low-density lipoprotein particle clearance);GO:0034379(very-low-density lipoprotein particle assembly);GO:0015485(cholesterol binding);GO:0034736(cholesterol O-acyltransferase activity);GO:0010742(macrophage derived foam cell differentiation);GO:0034435(cholesterol esterification);GO:0004772(sterol O-acyltransferase activity);GO:0010878(cholesterol storage);GO:0042986(positive regulation of amyloid precursor protein biosynthetic process)","00100(Steroid biosynthesis);04979(Cholesterol metabolism)","NA","NA","sterol O-acyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:11177]",{"v":0.086195,"d":"0.09"},{"v":0.104988,"d":"0.10"},{"v":0.820998590315084,"d":"0.82"},{"v":-0.28454835004285,"d":"-0.28"},1,1,"down","no"]
[52024,0,"chr13","+",113548303,113554590,"ENST00000620021",4,3542,"MSTRG.4120","TMCO3","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0055085(transmembrane transport);GO:0098655(cation transmembrane transport);GO:0006811(ion transport);GO:0015297(antiporter activity);GO:0015299(solute:proton antiporter activity);GO:0006812(cation transport);GO:1902600(hydrogen ion transmembrane transport);GO:0022890(inorganic cation transmembrane transporter activity)","NA","NA","NA","transmembrane and coiled-coil domains 3 [Source:HGNC Symbol;Acc:HGNC:20329]",{"v":0.014997,"d":"0.01"},0,"inf","inf",1,1,"up","no"]
[30250,0,"chr11","-",62662817,62671769,"ENST00000354588",7,1320,"MSTRG.2467","LBHD1","NA","NA","NA","NA","LBH domain containing 1 [Source:HGNC Symbol;Acc:HGNC:28351]",{"v":0.073395,"d":"0.07"},0,"inf","inf",1,1,"up","no"]
[149512,0,"chr4","-",99072152,99088751,"ENST00000626055",8,1299,"MSTRG.11744","ADH5","GO:0005737(cytoplasm);GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0006069(ethanol oxidation);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0051775(response to redox state);GO:0009055(electron carrier activity);GO:0005504(fatty acid binding);GO:0004022(alcohol dehydrogenase (NAD) activity);GO:0018467(formaldehyde dehydrogenase activity);GO:0042803(protein homodimerization activity);GO:0051903(S-(hydroxymethyl)glutathione dehydrogenase activity);GO:0001523(retinoid metabolic process);GO:0003016(respiratory system process);GO:0018119(peptidyl-cysteine S-nitrosylation);GO:0032496(response to lipopolysaccharide);GO:0045777(positive regulation of blood pressure);GO:0046294(formaldehyde catabolic process);GO:0051409(response to nitrosative stress);GO:0005739(mitochondrion)","00010(Glycolysis / Gluconeogenesis);00071(Fatty acid degradation);00350(Tyrosine metabolism);00830(Retinol metabolism);00980(Metabolism of xenobiotics by cytochrome P450);00982(Drug metabolism - cytochrome P450);05204(Chemical carcinogenesis)","NA","NA","alcohol dehydrogenase 5 (class III), chi polypeptide [Source:HGNC Symbol;Acc:HGNC:253]",0,{"v":0.081398,"d":"0.08"},"-inf","-inf",1,1,"down","no"]
[120416,0,"chr2","-",233556586,233566782,"ENST00000484528",5,933,"ENSG00000085982","USP40","GO:0016579(protein deubiquitination);GO:0016787(hydrolase activity);GO:0008233(peptidase activity);GO:0008234(cysteine-type peptidase activity);GO:0006508(proteolysis);GO:0006511(ubiquitin-dependent protein catabolic process);GO:0036459(thiol-dependent ubiquitinyl hydrolase activity)","NA","NA","NA","ubiquitin specific peptidase 40 [Source:HGNC Symbol;Acc:HGNC:20069]",{"v":0.096136,"d":"0.10"},{"v":0.013885,"d":"0.01"},{"v":6.92373064458048,"d":"6.92"},{"v":2.79154960031305,"d":"2.79"},1,1,"up","no"]
[200204,0,"chrX","+",135889205,135913060,"ENST00000324447",20,2952,"ENSG00000181433","SAGE1","NA","NA","NA","NA","sarcoma antigen 1 [Source:HGNC Symbol;Acc:HGNC:30369]",{"v":0.018412,"d":"0.02"},0,"inf","inf",1,1,"up","no"]
[81059,0,"chr17","+",27640387,27643581,"ENST00000583671",3,555,"MSTRG.6531","LGALS9","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0030246(carbohydrate binding);GO:0004871(signal transducer activity);GO:0005576(extracellular region);GO:0005615(extracellular space);GO:0002376(immune system process);GO:0006935(chemotaxis);GO:0006954(inflammatory response);GO:0070062(extracellular exosome);GO:0098586(cellular response to virus);GO:0010628(positive regulation of gene expression);GO:0005622(intracellular);GO:0032496(response to lipopolysaccharide);GO:0071346(cellular response to interferon-gamma);GO:0043123(positive regulation of I-kappaB kinase/NF-kappaB signaling);GO:0005534(galactose binding);GO:0019899(enzyme binding);GO:0048030(disaccharide binding);GO:0002519(natural killer cell tolerance induction);GO:0007565(female pregnancy);GO:0010629(negative regulation of gene expression);GO:0032682(negative regulation of chemokine production);GO:0032689(negative regulation of interferon-gamma production);GO:0032720(negative regulation of tumor necrosis factor production);GO:0032753(positive regulation of interleukin-4 production);GO:0032834(positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation involved in immune response);GO:0038066(p38MAPK cascade);GO:0042346(positive regulation of NF-kappaB import into nucleus);GO:0043305(negative regulation of mast cell degranulation);GO:0045953(negative regulation of natural killer cell mediated cytotoxicity);GO:0046007(negative regulation of activated T cell proliferation);GO:0046598(positive regulation of viral entry into host cell);GO:0050718(positive regulation of interleukin-1 beta secretion);GO:0051092(positive regulation of NF-kappaB transcription factor activity);GO:0060135(maternal process involved in female pregnancy);GO:0070241(positive regulation of activated T cell autonomous cell death);GO:0070371(ERK1 and ERK2 cascade);GO:0070374(positive regulation of ERK1 and ERK2 cascade);GO:0070555(response to interleukin-1);GO:0071636(positive regulation of transforming growth factor beta production);GO:0071639(positive regulation of monocyte chemotactic protein-1 production);GO:1902715(positive regulation of interferon-gamma secretion);GO:1904469(positive regulation of tumor necrosis factor secretion);GO:2000484(positive regulation of interleukin-8 secretion);GO:2000510(positive regulation of dendritic cell chemotaxis);GO:2000562(negative regulation of CD4-positive, alpha-beta T cell proliferation);GO:2000563(positive regulation of CD4-positive, alpha-beta T cell proliferation);GO:2000667(positive regulation of interleukin-13 secretion);GO:2000670(positive regulation of dendritic cell apoptotic process);GO:2000778(positive regulation of interleukin-6 secretion);GO:2001181(positive regulation of interleukin-10 secretion);GO:2001184(positive regulation of interleukin-12 secretion);GO:2001190(positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell);GO:2001200(positive regulation of dendritic cell differentiation);GO:2001269(positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway)","NA","NA","NA","galectin 9 [Source:HGNC Symbol;Acc:HGNC:6570]",{"v":0.063158,"d":"0.06"},{"v":0.149654,"d":"0.15"},{"v":0.422026808504951,"d":"0.42"},{"v":-1.24459344839876,"d":"-1.24"},1,1,"down","no"]
[74673,0,"chr16","+",67884805,67886372,"ENST00000339176",3,710,"MSTRG.6038","NRN1L","GO:0016020(membrane);GO:0005886(plasma membrane);GO:0007399(nervous system development);GO:0031225(anchored component of membrane);GO:0005576(extracellular region);GO:0006501(C-terminal protein lipidation);GO:0042803(protein homodimerization activity);GO:0046982(protein heterodimerization activity);GO:1990138(neuron projection extension);GO:0005615(extracellular space);GO:0030424(axon);GO:0046658(anchored component of plasma membrane)","NA","NA","NA","neuritin 1 like [Source:HGNC Symbol;Acc:HGNC:29811]",{"v":0.16012,"d":"0.16"},{"v":0.234294,"d":"0.23"},{"v":0.6834148548405,"d":"0.68"},{"v":-0.549166488074519,"d":"-0.55"},1,1,"down","no"]
[87575,0,"chr17","-",73209605,73232320,"ENST00000583024",3,417,"MSTRG.7167","FAM104A","GO:0005515(protein binding)","NA","NA","NA","family with sequence similarity 104 member A [Source:HGNC Symbol;Acc:HGNC:25918]",{"v":0.037546,"d":"0.04"},{"v":0.018824,"d":"0.02"},{"v":1.99458138546536,"d":"1.99"},{"v":0.996085991317682,"d":"1.00"},1,1,"up","no"]
[47646,0,"chr12","+",121400129,121418740,"ENST00000553407",4,1612,"MSTRG.3806","RNF34","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016607(nuclear speck);GO:0016020(membrane);GO:0046872(metal ion binding);GO:0005654(nucleoplasm);GO:0016740(transferase activity);GO:0016567(protein ubiquitination);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0016604(nuclear body);GO:0006915(apoptotic process);GO:0061630(ubiquitin protein ligase activity);GO:0012505(endomembrane system);GO:0042787(protein ubiquitination involved in ubiquitin-dependent protein catabolic process);GO:0031625(ubiquitin protein ligase binding);GO:0043161(proteasome-mediated ubiquitin-dependent protein catabolic process);GO:0070936(protein K48-linked ubiquitination);GO:0002039(p53 binding);GO:1901797(negative regulation of signal transduction by p53 class mediator);GO:2001271(negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis);GO:1902042(negative regulation of extrinsic apoptotic signaling pathway via death domain receptors);GO:1901981(phosphatidylinositol phosphate binding);GO:0035872(nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway);GO:2000374(regulation of oxygen metabolic process);GO:0004842(ubiquitin-protein transferase activity);GO:0070417(cellular response to cold)","NA","NA","NA","ring finger protein 34 [Source:HGNC Symbol;Acc:HGNC:17297]",{"v":0.402833,"d":"0.40"},{"v":0.171439,"d":"0.17"},{"v":2.34971622559628,"d":"2.35"},{"v":1.23248653353686,"d":"1.23"},1,1,"up","no"]
[32898,0,"chr11","-",73307235,73309361,"ENST00000546324",3,1695,"ENSG00000257038","AP002761.3","NA","NA","NA","NA","NA",{"v":0.034074,"d":"0.03"},{"v":0.026342,"d":"0.03"},{"v":1.29352365044416,"d":"1.29"},{"v":0.371306432118189,"d":"0.37"},1,1,"up","no"]
[43183,0,"chr12","-",56670450,56670746,"ENST00000482040",1,297,"MSTRG.3467","RN7SL809P","NA","NA","NA","NA","RNA, 7SL, cytoplasmic 809, pseudogene [Source:HGNC Symbol;Acc:HGNC:46825]",{"v":0.212399,"d":"0.21"},0,"inf","inf",1,1,"up","no"]
[65988,0,"chr15","-",85205440,85234785,"ENST00000560756",6,1160,"ENSG00000229212","AC044860.1","NA","NA","NA","NA","NA",{"v":0.132829,"d":"0.13"},{"v":0.072054,"d":"0.07"},{"v":1.84346462375441,"d":"1.84"},{"v":0.882419731254739,"d":"0.88"},1,1,"up","no"]
[55303,0,"chr14","+",56585855,56618663,"ENST00000556929",6,547,"ENSG00000070269","TMEM260","GO:0016020(membrane);GO:0016021(integral component of membrane)","NA","NA","NA","transmembrane protein 260 [Source:HGNC Symbol;Acc:HGNC:20185]",{"v":0.147037,"d":"0.15"},0,"inf","inf",1,1,"up","no"]
[134861,0,"chr3","+",38501162,38524246,"ENST00000483749",4,871,"ENSG00000157036","EXOG","GO:0003676(nucleic acid binding);GO:0016020(membrane);GO:0046872(metal ion binding);GO:0016787(hydrolase activity);GO:0005743(mitochondrial inner membrane);GO:0005739(mitochondrion);GO:0090305(nucleic acid phosphodiester bond hydrolysis);GO:0004519(endonuclease activity);GO:0004518(nuclease activity);GO:0008150(biological_process);GO:0005575(cellular_component);GO:0043234(protein complex);GO:0008409(5'-3' exonuclease activity);GO:0016021(integral component of membrane)","NA","NA","NA","exo/endonuclease G [Source:HGNC Symbol;Acc:HGNC:3347]",{"v":0.159965,"d":"0.16"},{"v":0.034063,"d":"0.03"},{"v":4.69615124915598,"d":"4.70"},{"v":2.23147887414075,"d":"2.23"},1,1,"up","no"]
[68498,0,"chr16","+",2752638,2761707,"ENST00000575009",10,1146,"MSTRG.5569","SRRM2","GO:0016607(nuclear speck);GO:0003723(RNA binding);GO:0006397(mRNA processing);GO:0008380(RNA splicing);GO:0005634(nucleus);GO:0005681(spliceosomal complex);GO:0005654(nucleoplasm);GO:0000398(mRNA splicing, via spliceosome);GO:0047485(protein N-terminus binding);GO:0015030(Cajal body);GO:0071013(catalytic step 2 spliceosome);GO:0070742(C2H2 zinc finger domain binding)","NA","NA","NA","serine/arginine repetitive matrix 2 [Source:HGNC Symbol;Acc:HGNC:16639]",{"v":0.043829,"d":"0.04"},0,"inf","inf",1,1,"up","no"]
[15285,0,"chr1","+",205504599,205532793,"ENST00000360066",16,3141,"ENSG00000117266","CDK18","GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0005515(protein binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005575(cellular_component)","NA","NA","NA","cyclin dependent kinase 18 [Source:HGNC Symbol;Acc:HGNC:8751]",0,0,1,0,1,1,"no","no"]
[30761,0,"chr11","+",64318182,64321742,"ENST00000347941",4,463,"MSTRG.2508","PRDX5","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0005739(mitochondrion);GO:0045454(cell redox homeostasis);GO:0048471(perinuclear region of cytoplasm);GO:0005615(extracellular space);GO:0031410(cytoplasmic vesicle);GO:0098869(cellular oxidant detoxification);GO:0006954(inflammatory response);GO:0005777(peroxisome);GO:0004601(peroxidase activity);GO:0043231(intracellular membrane-bounded organelle);GO:0070062(extracellular exosome);GO:0005759(mitochondrial matrix);GO:0005102(receptor binding);GO:0016480(negative regulation of transcription from RNA polymerase III promoter);GO:0043066(negative regulation of apoptotic process);GO:0006979(response to oxidative stress);GO:0034599(cellular response to oxidative stress);GO:0043027(cysteine-type endopeptidase inhibitor activity involved in apoptotic process);GO:0043154(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process);GO:0046983(protein dimerization activity);GO:0016209(antioxidant activity);GO:0006915(apoptotic process);GO:0034614(cellular response to reactive oxygen species);GO:0051920(peroxiredoxin activity);GO:0001016(RNA polymerase III regulatory region DNA binding);GO:0008379(thioredoxin peroxidase activity)","04146(Peroxisome)","K11187","EC:1.11.1.15","peroxiredoxin 5 [Source:HGNC Symbol;Acc:HGNC:9355]",{"v":0.320715,"d":"0.32"},{"v":1.546379,"d":"1.55"},{"v":0.207397410337311,"d":"0.21"},{"v":-2.26953021480008,"d":"-2.27"},1,1,"down","no"]
[201074,0,"chrX","-",153943058,153944232,"ENST00000464227",4,424,"MSTRG.15503","RENBP","GO:0016853(isomerase activity);GO:0003824(catalytic activity);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0004866(endopeptidase inhibitor activity);GO:0006048(UDP-N-acetylglucosamine biosynthetic process);GO:0008217(regulation of blood pressure);GO:0004857(enzyme inhibitor activity);GO:0005524(ATP binding);GO:0017076(purine nucleotide binding);GO:0042803(protein homodimerization activity);GO:0050121(N-acylglucosamine 2-epimerase activity);GO:0006044(N-acetylglucosamine metabolic process);GO:0006051(N-acetylmannosamine metabolic process);GO:0010951(negative regulation of endopeptidase activity);GO:0019262(N-acetylneuraminate catabolic process);GO:0043086(negative regulation of catalytic activity)","00520(Amino sugar and nucleotide sugar metabolism)","NA","NA","renin binding protein [Source:HGNC Symbol;Acc:HGNC:9959]",{"v":0.002204,"d":"0.00"},0,"inf","inf",1,1,"up","no"]
[19765,0,"chr10","+",38010693,38017707,"ENST00000476504",4,706,"ENSG00000189180","ZNF33A","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0005622(intracellular);GO:0003700(transcription factor activity, sequence-specific DNA binding)","NA","NA","NA","zinc finger protein 33A [Source:HGNC Symbol;Acc:HGNC:13096]",{"v":0.075668,"d":"0.08"},0,"inf","inf",1,1,"up","no"]
[200306,0,"chrX","-",136873449,136880725,"ENST00000464781",8,1852,"MSTRG.15469","RBMX","GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0006397(mRNA processing);GO:0008380(RNA splicing);GO:0005634(nucleus);GO:0016020(membrane);GO:0006351(transcription, DNA-templated);GO:0030529(intracellular ribonucleoprotein complex);GO:0005515(protein binding);GO:0005681(spliceosomal complex);GO:0005615(extracellular space);GO:0042802(identical protein binding);GO:0003729(mRNA binding);GO:0001047(core promoter binding);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0005654(nucleoplasm);GO:0070062(extracellular exosome);GO:0006366(transcription from RNA polymerase II promoter);GO:0003682(chromatin binding);GO:0071347(cellular response to interleukin-1);GO:0000398(mRNA splicing, via spliceosome);GO:0019904(protein domain specific binding);GO:0051259(protein oligomerization);GO:0000381(regulation of alternative mRNA splicing, via spliceosome);GO:0048025(negative regulation of mRNA splicing, via spliceosome);GO:0006509(membrane protein ectodomain proteolysis);GO:0016070(RNA metabolic process);GO:0051260(protein homooligomerization);GO:0071013(catalytic step 2 spliceosome);GO:0001649(osteoblast differentiation);GO:0005719(nuclear euchromatin);GO:0048026(positive regulation of mRNA splicing, via spliceosome);GO:0044530(supraspliceosomal complex);GO:0003727(single-stranded RNA binding);GO:0006376(mRNA splice site selection);GO:0045893(positive regulation of transcription, DNA-templated)","03040(Spliceosome)","K12885","NA","RNA binding motif protein, X-linked [Source:HGNC Symbol;Acc:HGNC:9910]",{"v":0.12646,"d":"0.13"},{"v":0.1527,"d":"0.15"},{"v":0.828159790438769,"d":"0.83"},{"v":-0.272018937510218,"d":"-0.27"},1,1,"down","no"]
[29823,0,"chr11","+",61004411,61007713,"ENST00000538288",3,423,"MSTRG.2438","CD6","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0007155(cell adhesion);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0005044(scavenger receptor activity);GO:0006898(receptor-mediated endocytosis);GO:0002376(immune system process);GO:0045087(innate immune response);GO:0002250(adaptive immune response);GO:0042102(positive regulation of T cell proliferation);GO:0032496(response to lipopolysaccharide);GO:0005887(integral component of plasma membrane);GO:0001530(lipopolysaccharide binding);GO:0031226(intrinsic component of plasma membrane);GO:0001772(immunological synapse);GO:0007157(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules);GO:0042101(T cell receptor complex);GO:0031663(lipopolysaccharide-mediated signaling pathway);GO:0001771(immunological synapse formation);GO:0070891(lipoteichoic acid binding);GO:0002438(acute inflammatory response to antigenic stimulus);GO:1900017(positive regulation of cytokine production involved in inflammatory response)","04514(Cell adhesion molecules (CAMs))","NA","NA","CD6 molecule [Source:HGNC Symbol;Acc:HGNC:1691]",{"v":0.027012,"d":"0.03"},{"v":0.098659,"d":"0.10"},{"v":0.273791544613264,"d":"0.27"},{"v":-1.8688502017352,"d":"-1.87"},1,1,"down","no"]
[10720,0,"chr1","+",151036570,151047600,"ENST00000368931",10,2143,"MSTRG.940","BNIPL","GO:0005634(nucleus);GO:0005829(cytosol);GO:0006915(apoptotic process);GO:0005515(protein binding);GO:0008285(negative regulation of cell proliferation);GO:0042802(identical protein binding);GO:0040009(regulation of growth rate)","NA","NA","NA","BCL2 interacting protein like [Source:HGNC Symbol;Acc:HGNC:16976]",{"v":0.146492,"d":"0.15"},0,"inf","inf",1,1,"up","no"]
[30957,0,"chr11","+",65014192,65022160,"ENST00000533729",4,795,"MSTRG.2525","ARL2","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005794(Golgi apparatus);GO:0005525(GTP binding);GO:0007264(small GTPase mediated signal transduction);GO:0000166(nucleotide binding);GO:0005730(nucleolus);GO:0005829(cytosol);GO:0005622(intracellular);GO:0005925(focal adhesion);GO:0005739(mitochondrion);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0007049(cell cycle);GO:0003924(GTPase activity);GO:0005813(centrosome);GO:0005815(microtubule organizing center);GO:0005758(mitochondrial intermembrane space);GO:0070062(extracellular exosome);GO:0005759(mitochondrial matrix);GO:0007098(centrosome cycle);GO:0016328(lateral plasma membrane);GO:0005095(GTPase inhibitor activity);GO:0050796(regulation of insulin secretion);GO:0070830(bicellular tight junction assembly);GO:0010811(positive regulation of cell-substrate adhesion);GO:0031113(regulation of microtubule polymerization);GO:0031116(positive regulation of microtubule polymerization);GO:0051457(maintenance of protein location in nucleus);GO:0034260(negative regulation of GTPase activity);GO:0007021(tubulin complex assembly)","NA","NA","NA","ADP ribosylation factor like GTPase 2 [Source:HGNC Symbol;Acc:HGNC:693]",{"v":0.382208,"d":"0.38"},{"v":0.577606,"d":"0.58"},{"v":0.661710577798707,"d":"0.66"},{"v":-0.595727752893847,"d":"-0.60"},1,1,"down","no"]
[193050,0,"chr9","+",121268168,121332843,"ENST00000449733",19,2702,"MSTRG.14938","GSN","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0005509(calcium ion binding);GO:0051015(actin filament binding);GO:0003779(actin binding);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0051016(barbed-end actin filament capping);GO:0051693(actin filament capping);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0005615(extracellular space);GO:0045010(actin nucleation);GO:0005925(focal adhesion);GO:0051014(actin filament severing);GO:0060271(cilium assembly);GO:0070062(extracellular exosome);GO:0031648(protein destabilization);GO:0010628(positive regulation of gene expression);GO:0044267(cellular protein metabolic process);GO:0002102(podosome);GO:0030030(cell projection organization);GO:0072562(blood microparticle);GO:0043312(neutrophil degranulation);GO:0030041(actin filament polymerization);GO:2001269(positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway);GO:0019904(protein domain specific binding);GO:0034774(secretory granule lumen);GO:1904813(ficolin-1-rich granule lumen);GO:0015629(actin cytoskeleton);GO:0030864(cortical actin cytoskeleton);GO:0046597(negative regulation of viral entry into host cell);GO:0045159(myosin II binding);GO:0006911(phagocytosis, engulfment);GO:0014891(striated muscle atrophy);GO:0042989(sequestering of actin monomers);GO:0051127(positive regulation of actin nucleation);GO:0071801(regulation of podosome assembly);GO:0090527(actin filament reorganization);GO:0097017(renal protein absorption);GO:0097284(hepatocyte apoptotic process);GO:1902174(positive regulation of keratinocyte apoptotic process);GO:1903689(regulation of wound healing, spreading of epidermal cells);GO:1903903(regulation of establishment of T cell polarity);GO:1903906(regulation of plasma membrane raft polarization);GO:1903909(regulation of receptor clustering);GO:1903923(positive regulation of protein processing in phagocytic vesicle);GO:1990000(amyloid fibril formation);GO:0016528(sarcoplasm);GO:0030478(actin cap);GO:0006915(apoptotic process);GO:0007568(aging);GO:0008154(actin polymerization or depolymerization);GO:0014003(oligodendrocyte development);GO:0016192(vesicle-mediated transport);GO:0030155(regulation of cell adhesion);GO:0042060(wound healing);GO:0042246(tissue regeneration);GO:0045471(response to ethanol);GO:0048015(phosphatidylinositol-mediated signaling);GO:0051593(response to folic acid);GO:0071276(cellular response to cadmium ion);GO:0001726(ruffle);GO:0030027(lamellipodium);GO:0043209(myelin sheath);GO:0043234(protein complex);GO:0048471(perinuclear region of cytoplasm)","04810(Regulation of actin cytoskeleton);04666(Fc gamma R-mediated phagocytosis);05203(Viral carcinogenesis)","K05768","NA","gelsolin [Source:HGNC Symbol;Acc:HGNC:4620]",{"v":0.155806,"d":"0.16"},{"v":0.005397,"d":"0.01"},{"v":28.8690012970169,"d":"28.87"},{"v":4.85144929429489,"d":"4.85"},1,1,"up","no"]
[141172,0,"chr3","+",141386446,141404006,"ENST00000513249",2,572,"ENSG00000177311","ZBTB38","GO:0003676(nucleic acid binding);GO:0005654(nucleoplasm);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0005694(chromosome);GO:0042803(protein homodimerization activity);GO:0006974(cellular response to DNA damage stimulus);GO:0005515(protein binding);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0072562(blood microparticle);GO:0045892(negative regulation of transcription, DNA-templated);GO:0008327(methyl-CpG binding);GO:0006275(regulation of DNA replication)","NA","NA","NA","zinc finger and BTB domain containing 38 [Source:HGNC Symbol;Acc:HGNC:26636]",0,{"v":0.177943,"d":"0.18"},"-inf","-inf",1,1,"down","no"]
[5877,0,"chr1","-",48634208,50023913,"ENST00000371838",9,1353,"ENSG00000186094","AGBL4","GO:0005737(cytoplasm);GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0016787(hydrolase activity);GO:0005794(Golgi apparatus);GO:0005829(cytosol);GO:0005856(cytoskeleton);GO:0042995(cell projection);GO:0008233(peptidase activity);GO:0006508(proteolysis);GO:0004181(metallocarboxypeptidase activity);GO:0004180(carboxypeptidase activity);GO:0008237(metallopeptidase activity);GO:0051607(defense response to virus);GO:0005814(centriole);GO:0036064(ciliary basal body);GO:0015631(tubulin binding);GO:0035610(protein side chain deglutamylation);GO:0035608(protein deglutamylation);GO:0035609(C-terminal protein deglutamylation)","NA","NA","NA","ATP/GTP binding protein like 4 [Source:HGNC Symbol;Acc:HGNC:25892]",0,0,1,0,1,1,"no","no"]
[190942,0,"chr9","-",69718021,69723571,"ENST00000415701",3,826,"ENSG00000188647","PTAR1","GO:0008318(protein prenyltransferase activity);GO:0018342(protein prenylation);GO:0016740(transferase activity);GO:0005737(cytoplasm);GO:0004659(prenyltransferase activity);GO:1990234(transferase complex)","NA","NA","NA","protein prenyltransferase alpha subunit repeat containing 1 [Source:HGNC Symbol;Acc:HGNC:30449]",{"v":0.045556,"d":"0.05"},0,"inf","inf",1,1,"up","no"]
[177508,0,"chr7","-",105160301,105203732,"ENST00000476117",5,703,"MSTRG.13865","SRPK2","GO:0008284(positive regulation of cell proliferation);GO:0010628(positive regulation of gene expression);GO:0045787(positive regulation of cell cycle);GO:0003723(RNA binding);GO:0006397(mRNA processing);GO:0008380(RNA splicing);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0005730(nucleolus);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0005515(protein binding);GO:0000287(magnesium ion binding);GO:0030154(cell differentiation);GO:0045087(innate immune response);GO:0045070(positive regulation of viral genome replication);GO:0035556(intracellular signal transduction);GO:0001525(angiogenesis);GO:0048024(regulation of mRNA splicing, via spliceosome);GO:0000245(spliceosomal complex assembly);GO:0045071(negative regulation of viral genome replication);GO:0071889(14-3-3 protein binding);GO:0035063(nuclear speck organization);GO:0043525(positive regulation of neuron apoptotic process)","NA","NA","NA","SRSF protein kinase 2 [Source:HGNC Symbol;Acc:HGNC:11306]",0,0,1,0,1,1,"no","no"]
[161566,0,"chr5","+",177404406,177434030,"ENST00000506296",9,955,"MSTRG.12577","GRK6","GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0007165(signal transduction);GO:0004703(G-protein coupled receptor kinase activity);GO:0016020(membrane);GO:0005515(protein binding);GO:0016055(Wnt signaling pathway);GO:0005886(plasma membrane);GO:0008277(regulation of G-protein coupled receptor protein signaling pathway);GO:0047696(beta-adrenergic receptor kinase activity)","04144(Endocytosis);04062(Chemokine signaling pathway);05032(Morphine addiction)","NA","NA","G protein-coupled receptor kinase 6 [Source:HGNC Symbol;Acc:HGNC:4545]",0,{"v":0.000218,"d":"0.00"},"-inf","-inf",1,1,"down","no"]
[20383,0,"chr10","+",50676743,50686326,"ENST00000442076",8,2498,"ENSG00000232706","NUTM2HP","NA","NA","NA","NA","NUT family member 2H, pseudogene [Source:HGNC Symbol;Acc:HGNC:45017]",{"v":0.03421,"d":"0.03"},0,"inf","inf",1,1,"up","no"]
[104888,0,"chr19","+",52269593,52291761,"ENST00000599581",5,2065,"ENSG00000196214","ZNF766","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0005622(intracellular)","NA","NA","NA","zinc finger protein 766 [Source:HGNC Symbol;Acc:HGNC:28063]",{"v":0.777709,"d":"0.78"},0,"inf","inf",1,1,"up","no"]
[174485,0,"chr7","+",64666083,64711582,"ENST00000613690",3,5589,"ENSG00000196247","ZNF107","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0003674(molecular_function);GO:0008150(biological_process);GO:0005575(cellular_component);GO:0005622(intracellular)","NA","NA","NA","zinc finger protein 107 [Source:HGNC Symbol;Acc:HGNC:12887]",0,{"v":0.011187,"d":"0.01"},"-inf","-inf",1,1,"down","no"]
[172696,0,"chr7","+",27828700,27833151,"ENST00000460059",2,527,"MSTRG.13536","TAX1BP1","GO:0046872(metal ion binding);GO:0005515(protein binding);GO:0006915(apoptotic process);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0043066(negative regulation of apoptotic process);GO:0010803(regulation of tumor necrosis factor-mediated signaling pathway);GO:0032480(negative regulation of type I interferon production);GO:0032088(negative regulation of NF-kappaB transcription factor activity);GO:0019900(kinase binding)","04137(Mitophagy - animal)","NA","NA","Tax1 binding protein 1 [Source:HGNC Symbol;Acc:HGNC:11575]",{"v":1.548403,"d":"1.55"},{"v":1.06783,"d":"1.07"},{"v":1.45004635569332,"d":"1.45"},{"v":0.536099021660819,"d":"0.54"},1,1,"up","no"]
[117030,0,"chr2","-",181676467,181680876,"ENST00000295108",2,2852,"MSTRG.9288","NEUROD1","GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0046983(protein dimerization activity);GO:0006355(regulation of transcription, DNA-templated);GO:0006366(transcription from RNA polymerase II promoter);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0007399(nervous system development);GO:0007275(multicellular organism development);GO:0030154(cell differentiation);GO:0003713(transcription coactivator activity);GO:0045893(positive regulation of transcription, DNA-templated);GO:0048666(neuron development);GO:0005515(protein binding);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:0001077(transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0003682(chromatin binding);GO:0003690(double-stranded DNA binding);GO:0043565(sequence-specific DNA binding);GO:0046982(protein heterodimerization activity);GO:0070888(E-box binding);GO:0003326(pancreatic A cell fate commitment);GO:0003329(pancreatic PP cell fate commitment);GO:0006913(nucleocytoplasmic transport);GO:0009952(anterior/posterior pattern specification);GO:0021542(dentate gyrus development);GO:0021549(cerebellum development);GO:0023019(signal transduction involved in regulation of gene expression);GO:0030902(hindbrain development);GO:0031018(endocrine pancreas development);GO:0035881(amacrine cell differentiation);GO:0035883(enteroendocrine cell differentiation);GO:0042493(response to drug);GO:0042593(glucose homeostasis);GO:0043010(camera-type eye development);GO:0043065(positive regulation of apoptotic process);GO:0045165(cell fate commitment);GO:0045597(positive regulation of cell differentiation);GO:0045664(regulation of neuron differentiation);GO:0045666(positive regulation of neuron differentiation);GO:0046426(negative regulation of JAK-STAT cascade);GO:0048562(embryonic organ morphogenesis);GO:0048839(inner ear development);GO:0051091(positive regulation of sequence-specific DNA binding transcription factor activity);GO:0060730(regulation of intestinal epithelial structure maintenance);GO:0071156(regulation of cell cycle arrest);GO:0071333(cellular response to glucose stimulus);GO:2000675(negative regulation of type B pancreatic cell apoptotic process);GO:0005622(intracellular);GO:0005654(nucleoplasm);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0090575(RNA polymerase II transcription factor complex);GO:0001102(RNA polymerase II activating transcription factor binding);GO:0008134(transcription factor binding);GO:0007263(nitric oxide mediated signal transduction);GO:2000679(positive regulation of transcription regulatory region DNA binding);GO:0050796(regulation of insulin secretion);GO:0009749(response to glucose);GO:0001105(RNA polymerase II transcription coactivator activity);GO:0030073(insulin secretion);GO:0022008(neurogenesis)","04950(Maturity onset diabetes of the young)","K08033","NA","neuronal differentiation 1 [Source:HGNC Symbol;Acc:HGNC:7762]",0,0,1,0,1,1,"no","no"]
[51331,0,"chr13","+",97434471,97464710,"ENST00000476869",3,903,"MSTRG.4046","RAP2A","GO:0016020(membrane);GO:0005525(GTP binding);GO:0000166(nucleotide binding);GO:0007165(signal transduction);GO:0003924(GTPase activity);GO:0005886(plasma membrane);GO:0030496(midbody);GO:0005515(protein binding);GO:0005768(endosome);GO:0070062(extracellular exosome);GO:0001934(positive regulation of protein phosphorylation);GO:0055037(recycling endosome);GO:0055038(recycling endosome membrane);GO:0035690(cellular response to drug);GO:0030033(microvillus assembly);GO:0031532(actin cytoskeleton reorganization);GO:0000287(magnesium ion binding);GO:0048814(regulation of dendrite morphogenesis);GO:0046328(regulation of JNK cascade);GO:0072659(protein localization to plasma membrane);GO:0031954(positive regulation of protein autophosphorylation);GO:0032486(Rap protein signal transduction);GO:0019003(GDP binding);GO:0030336(negative regulation of cell migration);GO:0034613(cellular protein localization);GO:0045184(establishment of protein localization);GO:0005829(cytosol)","NA","NA","NA","RAP2A, member of RAS oncogene family [Source:HGNC Symbol;Acc:HGNC:9861]",0,0,1,0,1,1,"no","no"]
[56857,0,"chr14","+",74881903,74892943,"ENST00000555492",7,569,"MSTRG.4545","DLST","GO:0005634(nucleus);GO:0016020(membrane);GO:0016740(transferase activity);GO:0006099(tricarboxylic acid cycle);GO:0016746(transferase activity, transferring acyl groups);GO:0008152(metabolic process);GO:0005739(mitochondrion);GO:0004149(dihydrolipoyllysine-residue succinyltransferase activity);GO:0043209(myelin sheath);GO:0045252(oxoglutarate dehydrogenase complex);GO:0070062(extracellular exosome);GO:0006554(lysine catabolic process);GO:0005759(mitochondrial matrix);GO:0034641(cellular nitrogen compound metabolic process);GO:0006091(generation of precursor metabolites and energy);GO:0033512(L-lysine catabolic process to acetyl-CoA via saccharopine)","00020(Citrate cycle (TCA cycle));00310(Lysine degradation)","NA","NA","dihydrolipoamide S-succinyltransferase [Source:HGNC Symbol;Acc:HGNC:2911]",0,0,1,0,1,1,"no","no"]
[69638,0,"chr16","-",11348143,11349321,"ENST00000574681",2,1095,"ENSG00000262703","AC009121.1","NA","NA","NA","NA","NA",0,0,1,0,1,1,"no","no"]
[134881,0,"chr3","-",38845769,38950561,"ENST00000302328",26,6500,"ENSG00000168356","SCN11A","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0055085(transmembrane transport);GO:0005216(ion channel activity);GO:0006811(ion transport);GO:0034220(ion transmembrane transport);GO:0005244(voltage-gated ion channel activity);GO:0034765(regulation of ion transmembrane transport);GO:0005886(plasma membrane);GO:0006814(sodium ion transport);GO:0035725(sodium ion transmembrane transport);GO:0001518(voltage-gated sodium channel complex);GO:0005272(sodium channel activity);GO:0005248(voltage-gated sodium channel activity);GO:0060078(regulation of postsynaptic membrane potential);GO:0070062(extracellular exosome);GO:0086010(membrane depolarization during action potential);GO:0019228(neuronal action potential);GO:0042493(response to drug);GO:0051930(regulation of sensory perception of pain);GO:0030424(axon);GO:0044299(C-fiber)","NA","NA","NA","sodium voltage-gated channel alpha subunit 11 [Source:HGNC Symbol;Acc:HGNC:10583]",{"v":0.007956,"d":"0.01"},0,"inf","inf",1,1,"up","no"]
[59291,0,"chr14","-",104770155,104777678,"ENST00000544168",12,1564,"MSTRG.4729","AKT1","GO:0046326(positive regulation of glucose import);GO:0051091(positive regulation of sequence-specific DNA binding transcription factor activity);GO:0001934(positive regulation of protein phosphorylation);GO:0045600(positive regulation of fat cell differentiation);GO:0010507(negative regulation of autophagy);GO:0006810(transport);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0005829(cytosol);GO:0042803(protein homodimerization activity);GO:0005886(plasma membrane);GO:0015630(microtubule cytoskeleton);GO:0005515(protein binding);GO:0007165(signal transduction);GO:0006915(apoptotic process);GO:0007275(multicellular organism development);GO:0007399(nervous system development);GO:0030154(cell differentiation);GO:0060416(response to growth hormone);GO:0005975(carbohydrate metabolic process);GO:0008643(carbohydrate transport);GO:0042802(identical protein binding);GO:0098794(postsynapse);GO:0005654(nucleoplasm);GO:0033138(positive regulation of peptidyl-serine phosphorylation);GO:0061024(membrane organization);GO:0043488(regulation of mRNA stability);GO:0006417(regulation of translation);GO:0008283(cell proliferation);GO:0043234(protein complex);GO:0071356(cellular response to tumor necrosis factor);GO:0006006(glucose metabolic process);GO:0005547(phosphatidylinositol-3,4,5-trisphosphate binding);GO:0043325(phosphatidylinositol-3,4-bisphosphate binding);GO:0005080(protein kinase C binding);GO:0019899(enzyme binding);GO:0019901(protein kinase binding);GO:0032794(GTPase activating protein binding);GO:0051721(protein phosphatase 2A binding);GO:0001649(osteoblast differentiation);GO:0001893(maternal placenta development);GO:0005977(glycogen metabolic process);GO:0005978(glycogen biosynthetic process);GO:0006412(translation);GO:0006469(negative regulation of protein kinase activity);GO:0006954(inflammatory response);GO:0006974(cellular response to DNA damage stimulus);GO:0007281(germ cell development);GO:0007568(aging);GO:0008286(insulin receptor signaling pathway);GO:0008637(apoptotic mitochondrial changes);GO:0009725(response to hormone);GO:0010033(response to organic substance);GO:0010629(negative regulation of gene expression);GO:0010763(positive regulation of fibroblast migration);GO:0010765(positive regulation of sodium ion transport);GO:0010975(regulation of neuron projection development);GO:0015758(glucose transport);GO:0016567(protein ubiquitination);GO:0018105(peptidyl-serine phosphorylation);GO:0021510(spinal cord development);GO:0030030(cell projection organization);GO:0030163(protein catabolic process);GO:0030212(hyaluronan metabolic process);GO:0030307(positive regulation of cell growth);GO:0030334(regulation of cell migration);GO:0031641(regulation of myelination);GO:0031663(lipopolysaccharide-mediated signaling pathway);GO:0032094(response to food);GO:0032270(positive regulation of cellular protein metabolic process);GO:0032287(peripheral nervous system myelin maintenance);GO:0032436(positive regulation of proteasomal ubiquitin-dependent protein catabolic process);GO:0032869(cellular response to insulin stimulus);GO:0032880(regulation of protein localization);GO:0035924(cellular response to vascular endothelial growth factor stimulus);GO:0036294(cellular response to decreased oxygen levels);GO:0042593(glucose homeostasis);GO:0042981(regulation of apoptotic process);GO:0043065(positive regulation of apoptotic process);GO:0043066(negative regulation of apoptotic process);GO:0043154(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process);GO:0043491(protein kinase B signaling);GO:0045792(negative regulation of cell size);GO:0045907(positive regulation of vasoconstriction);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0046329(negative regulation of JNK cascade);GO:0046622(positive regulation of organ growth);GO:0051146(striated muscle cell differentiation);GO:0060709(glycogen cell differentiation involved in embryonic placenta development);GO:0060716(labyrinthine layer blood vessel development);GO:0071260(cellular response to mechanical stimulus);GO:0071363(cellular response to growth factor stimulus);GO:0071364(cellular response to epidermal growth factor stimulus);GO:0071380(cellular response to prostaglandin E stimulus);GO:0071407(cellular response to organic cyclic compound);GO:0071456(cellular response to hypoxia);GO:0090201(negative regulation of release of cytochrome c from mitochondria);GO:0097011(cellular response to granulocyte macrophage colony-stimulating factor stimulus);GO:0097194(execution phase of apoptosis);GO:1901653(cellular response to peptide);GO:1990090(cellular response to nerve growth factor stimulus);GO:1990418(response to insulin-like growth factor stimulus);GO:0005739(mitochondrion);GO:0005819(spindle);GO:0005911(cell-cell junction);GO:0036064(ciliary basal body);GO:0008284(positive regulation of cell proliferation);GO:0004712(protein serine/threonine/tyrosine kinase activity);GO:0007186(G-protein coupled receptor signaling pathway);GO:0030168(platelet activation);GO:1901796(regulation of signal transduction by p53 class mediator);GO:0031982(vesicle);GO:0006464(cellular protein modification process);GO:0000082(G1/S transition of mitotic cell cycle);GO:0014065(phosphatidylinositol 3-kinase signaling);GO:0014066(regulation of phosphatidylinositol 3-kinase signaling);GO:0038111(interleukin-7-mediated signaling pathway);GO:0048015(phosphatidylinositol-mediated signaling);GO:0050999(regulation of nitric-oxide synthase activity);GO:0046777(protein autophosphorylation);GO:0007173(epidermal growth factor receptor signaling pathway);GO:0051000(positive regulation of nitric-oxide synthase activity);GO:2001240(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand);GO:0018107(peptidyl-threonine phosphorylation);GO:0060644(mammary gland epithelial cell differentiation);GO:0071889(14-3-3 protein binding);GO:0007249(I-kappaB kinase/NF-kappaB signaling);GO:0034614(cellular response to reactive oxygen species);GO:0038061(NIK/NF-kappaB signaling);GO:0045893(positive regulation of transcription, DNA-templated);GO:0071276(cellular response to cadmium ion);GO:0031295(T cell costimulation);GO:0035556(intracellular signal transduction);GO:0090004(positive regulation of establishment of protein localization to plasma membrane);GO:0031018(endocrine pancreas development);GO:1901215(negative regulation of neuron death);GO:0045429(positive regulation of nitric oxide biosynthetic process);GO:0001938(positive regulation of endothelial cell proliferation);GO:0006979(response to oxidative stress);GO:0000060(protein import into nucleus, translocation);GO:1902176(negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway);GO:0006809(nitric oxide biosynthetic process);GO:0031659(positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle);GO:0070141(response to UV-A);GO:0045861(negative regulation of proteolysis);GO:0035655(interleukin-18-mediated signaling pathway);GO:0048661(positive regulation of smooth muscle cell proliferation);GO:0045725(positive regulation of glycogen biosynthetic process);GO:0046889(positive regulation of lipid biosynthetic process);GO:0010951(negative regulation of endopeptidase activity);GO:0048009(insulin-like growth factor receptor signaling pathway);GO:1900182(positive regulation of protein localization to nucleus);GO:0010748(negative regulation of plasma membrane long-chain fatty acid transport);GO:0043536(positive regulation of blood vessel endothelial cell migration);GO:0045742(positive regulation of epidermal growth factor receptor signaling pathway);GO:0099565(chemical synaptic transmission, postsynaptic);GO:0072655(establishment of protein localization to mitochondrion);GO:0072656(maintenance of protein location in mitochondrion);GO:0032079(positive regulation of endodeoxyribonuclease activity);GO:0034405(response to fluid shear stress);GO:0030235(nitric-oxide synthase regulator activity);GO:0005979(regulation of glycogen biosynthetic process);GO:0006924(activation-induced cell death of T cells);GO:0009408(response to heat);GO:0010907(positive regulation of glucose metabolic process);GO:0010918(positive regulation of mitochondrial membrane potential);GO:0016242(negative regulation of macroautophagy);GO:0031929(TOR signaling);GO:0031999(negative regulation of fatty acid beta-oxidation);GO:0043276(anoikis);GO:0100002(negative regulation of protein kinase activity by protein phosphorylation);GO:1901976(regulation of cell cycle checkpoint);GO:1903721(positive regulation of I-kappaB phosphorylation)","04014(Ras signaling pathway);04015(Rap1 signaling pathway);04010(MAPK signaling pathway);04012(ErbB signaling pathway);04370(VEGF signaling pathway);04371(Apelin signaling pathway);04630(Jak-STAT signaling pathway);04668(TNF signaling pathway);04066(HIF-1 signaling pathway);04068(FoxO signaling pathway);04072(Phospholipase D signaling pathway);04071(Sphingolipid signaling pathway);04024(cAMP signaling pathway);04022(cGMP - PKG signaling pathway);04151(PI3K-Akt signaling pathway);04152(AMPK signaling pathway);04150(mTOR signaling pathway);04140(Autophagy - animal);04210(Apoptosis);04218(Cellular senescence);04510(Focal adhesion);04550(Signaling pathways regulating pluripotency of stem cells);04611(Platelet activation);04620(Toll-like receptor signaling pathway);04660(T cell receptor signaling pathway);04662(B cell receptor signaling pathway);04664(Fc epsilon RI signaling pathway);04666(Fc gamma R-mediated phagocytosis);04062(Chemokine signaling pathway);04910(Insulin signaling pathway);04922(Glucagon signaling pathway);04923(Regulation of lipolysis in adipocyte);04920(Adipocytokine signaling pathway);04915(Estrogen signaling pathway);04914(Progesterone-mediated oocyte maturation);04917(Prolactin signaling pathway);04926(Relaxin signaling pathway);04919(Thyroid hormone signaling pathway);04261(Adrenergic signaling in cardiomyocytes);04973(Carbohydrate digestion and absorption);04725(Cholinergic synapse);04728(Dopaminergic synapse);04722(Neurotrophin signaling pathway);04380(Osteoclast differentiation);04211(Longevity regulating pathway - mammal);04213(Longevity regulating pathway - multiple species);05200(Pathways in cancer);05230(Central carbon metabolism in cancer);05231(Choline metabolism in cancer);05205(Proteoglycans in cancer);05210(Colorectal cancer);05212(Pancreatic cancer);05225(Hepatocellular carcinoma);05226(Gastric cancer);05214(Glioma);05221(Acute myeloid leukemia);05220(Chronic myeloid leukemia);05218(Melanoma);05211(Renal cell carcinoma);05215(Prostate cancer);05213(Endometrial cancer);05224(Breast cancer);05222(Small cell lung cancer);05223(Non-small cell lung cancer);05418(Fluid shear stress and atherosclerosis);04932(Non-alcoholic fatty liver disease (NAFLD));04931(Insulin resistance);04933(AGE-RAGE signaling pathway in diabetic complications);05152(Tuberculosis);05166(HTLV-I infection);05162(Measles);05164(Influenza A);05161(Hepatitis B);05160(Hepatitis C);05167(Kaposi's sarcoma-associated herpesvirus infection);05169(Epstein-Barr virus infection);05165(Human papillomavirus infection);05145(Toxoplasmosis);05142(Chagas disease (American trypanosomiasis));01521(EGFR tyrosine kinase inhibitor resistance);01524(Platinum drug resistance);01522(Endocrine resistance)","NA","NA","AKT serine/threonine kinase 1 [Source:HGNC Symbol;Acc:HGNC:391]",0,{"v":0.138646,"d":"0.14"},"-inf","-inf",1,1,"down","no"]
[38206,0,"chr12","-",6967747,6970680,"ENST00000544888",5,872,"MSTRG.3082","PHB2","GO:0016020(membrane);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0005739(mitochondrion);GO:0005743(mitochondrial inner membrane);GO:0005515(protein binding);GO:0005741(mitochondrial outer membrane);GO:0070062(extracellular exosome);GO:0050821(protein stabilization);GO:0071944(cell periphery);GO:0030331(estrogen receptor binding);GO:0043234(protein complex);GO:0008022(protein C-terminus binding);GO:0047485(protein N-terminus binding);GO:0043066(negative regulation of apoptotic process);GO:0070374(positive regulation of ERK1 and ERK2 cascade);GO:0009986(cell surface);GO:0043433(negative regulation of sequence-specific DNA binding transcription factor activity);GO:0045892(negative regulation of transcription, DNA-templated);GO:0016363(nuclear matrix);GO:0051091(positive regulation of sequence-specific DNA binding transcription factor activity);GO:0031536(positive regulation of exit from mitosis);GO:0007005(mitochondrion organization);GO:0007062(sister chromatid cohesion);GO:0006851(mitochondrial calcium ion transmembrane transport);GO:0000060(protein import into nucleus, translocation);GO:1902808(positive regulation of cell cycle G1/S phase transition);GO:0033218(amide binding);GO:0009611(response to wounding);GO:0033147(negative regulation of intracellular estrogen receptor signaling pathway);GO:0033600(negative regulation of mammary gland epithelial cell proliferation);GO:0060744(mammary gland branching involved in thelarche);GO:0060749(mammary gland alveolus development);GO:0060762(regulation of branching involved in mammary gland duct morphogenesis);GO:0071300(cellular response to retinoic acid);GO:0071456(cellular response to hypoxia);GO:0030424(axon)","NA","NA","NA","prohibitin 2 [Source:HGNC Symbol;Acc:HGNC:30306]",{"v":0.545408,"d":"0.55"},{"v":0.294686,"d":"0.29"},{"v":1.85081069341604,"d":"1.85"},{"v":0.888157339489008,"d":"0.89"},1,1,"up","no"]
[2418,0,"chr1","-",20825104,20847945,"ENST00000435383",5,616,"ENSG00000075151","EIF4G3","GO:0003723(RNA binding);GO:0003743(translation initiation factor activity);GO:0006412(translation);GO:0006413(translational initiation);GO:0005829(cytosol);GO:0006417(regulation of translation);GO:0016032(viral process);GO:0008135(translation factor activity, RNA binding);GO:0000339(RNA cap binding);GO:0006446(regulation of translational initiation);GO:0016281(eukaryotic translation initiation factor 4F complex)","03013(RNA transport);05416(Viral myocarditis)","NA","NA","eukaryotic translation initiation factor 4 gamma 3 [Source:HGNC Symbol;Acc:HGNC:3298]",{"v":0.122709,"d":"0.12"},0,"inf","inf",1,1,"up","no"]
[127924,0,"chr21","-",45285483,45287892,"ENST00000476653",2,598,"ENSG00000186866","POFUT2","GO:0016740(transferase activity);GO:0016757(transferase activity, transferring glycosyl groups);GO:0005794(Golgi apparatus);GO:0005783(endoplasmic reticulum);GO:0006486(protein glycosylation);GO:0005975(carbohydrate metabolic process);GO:0005789(endoplasmic reticulum membrane);GO:0006004(fucose metabolic process);GO:0036066(protein O-linked fucosylation);GO:0046922(peptide-O-fucosyltransferase activity);GO:0051046(regulation of secretion);GO:0008417(fucosyltransferase activity);GO:0001707(mesoderm formation);GO:0010468(regulation of gene expression);GO:0010717(regulation of epithelial to mesenchymal transition);GO:0036065(fucosylation)","00514(Other types of O-glycan biosynthesis)","NA","NA","protein O-fucosyltransferase 2 [Source:HGNC Symbol;Acc:HGNC:14683]",{"v":0.137087,"d":"0.14"},{"v":0.228815,"d":"0.23"},{"v":0.599117190743614,"d":"0.60"},{"v":-0.73908986488166,"d":"-0.74"},1,1,"down","no"]
[183560,"j","chr8","+",43182217,43200014,"MSTRG.14341.9",7,1915,"MSTRG.14341","HGSNAT","NA","NA","NA","NA","NA",0,0,1,0,1,1,"no","no"]
[43280,0,"chr12","-",57097105,57099794,"ENST00000555318",6,465,"MSTRG.3477","STAT6","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0006355(regulation of transcription, DNA-templated);GO:0006366(transcription from RNA polymerase II promoter);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0031965(nuclear membrane);GO:0007165(signal transduction);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0004871(signal transducer activity);GO:0005515(protein binding);GO:0042802(identical protein binding);GO:0001228(transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0019903(protein phosphatase binding);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0000977(RNA polymerase II regulatory region sequence-specific DNA binding);GO:0032481(positive regulation of type I interferon production);GO:0000979(RNA polymerase II core promoter sequence-specific DNA binding);GO:0043565(sequence-specific DNA binding);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0002296(T-helper 1 cell lineage commitment);GO:0002829(negative regulation of type 2 immune response);GO:0019221(cytokine-mediated signaling pathway);GO:0033598(mammary gland epithelial cell proliferation);GO:0034097(response to cytokine);GO:0035771(interleukin-4-mediated signaling pathway);GO:0042127(regulation of cell proliferation);GO:0048295(positive regulation of isotype switching to IgE isotypes);GO:0060443(mammary gland morphogenesis);GO:0070301(cellular response to hydrogen peroxide);GO:1902170(cellular response to reactive nitrogen species);GO:0000790(nuclear chromatin);GO:0045121(membrane raft)","04630(Jak-STAT signaling pathway);04217(Necroptosis);04658(Th1 and Th2 cell differentiation);04659(Th17 cell differentiation);05200(Pathways in cancer);05321(Inflammatiory bowel disease (IBD));05161(Hepatitis B)","NA","NA","signal transducer and activator of transcription 6 [Source:HGNC Symbol;Acc:HGNC:11368]",{"v":0.100584,"d":"0.10"},{"v":0.379096,"d":"0.38"},{"v":0.265325933272839,"d":"0.27"},{"v":-1.91416240169684,"d":"-1.91"},1,1,"down","no"]
[154101,0,"chr5","-",34913970,34916769,"ENST00000628399",3,1678,"ENSG00000113456","RAD1","GO:0005634(nucleus);GO:0043231(intracellular membrane-bounded organelle);GO:0005654(nucleoplasm);GO:0016787(hydrolase activity);GO:0005694(chromosome);GO:0000077(DNA damage checkpoint);GO:0090305(nucleic acid phosphodiester bond hydrolysis);GO:0005515(protein binding);GO:0006281(DNA repair);GO:0006974(cellular response to DNA damage stimulus);GO:0004527(exonuclease activity);GO:0004518(nuclease activity);GO:0021762(substantia nigra development);GO:1901796(regulation of signal transduction by p53 class mediator);GO:0006260(DNA replication);GO:0003684(damaged DNA binding);GO:0071479(cellular response to ionizing radiation);GO:0008408(3'-5' exonuclease activity);GO:0008853(exodeoxyribonuclease III activity);GO:0051598(meiotic recombination checkpoint);GO:0030896(checkpoint clamp complex)","04218(Cellular senescence)","NA","NA","RAD1 checkpoint DNA exonuclease [Source:HGNC Symbol;Acc:HGNC:9806]",0,0,1,0,1,1,"no","no"]
[1735,0,"chr1","+",13068677,13077884,"ENST00000614839",4,1863,"ENSG00000229571","PRAMEF25","GO:0043066(negative regulation of apoptotic process);GO:0008284(positive regulation of cell proliferation);GO:0045596(negative regulation of cell differentiation);GO:0045892(negative regulation of transcription, DNA-templated)","NA","NA","NA","PRAME family member 25 [Source:HGNC Symbol;Acc:HGNC:49179]",0,0,1,0,1,1,"no","no"]
[89185,0,"chr17","-",80966239,80971213,"ENST00000576234",2,3133,"ENSG00000261924","AC127496.1","NA","NA","NA","NA","NA",0,0,1,0,1,1,"no","no"]
[108433,0,"chr2","+",29097705,29174713,"ENST00000401605",15,2322,"ENSG00000115295","CLIP4","GO:0043231(intracellular membrane-bounded organelle);GO:0005515(protein binding);GO:0016020(membrane);GO:0016021(integral component of membrane)","NA","NA","NA","CAP-Gly domain containing linker protein family member 4 [Source:HGNC Symbol;Acc:HGNC:26108]",{"v":0.000354,"d":"0.00"},0,"inf","inf",1,1,"up","no"]
[59208,0,"chr14","+",103970597,104052665,"ENST00000557332",26,3338,"MSTRG.4705","TDRD9","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0016787(hydrolase activity);GO:0004386(helicase activity);GO:0007275(multicellular organism development);GO:0051321(meiotic cell cycle);GO:0030154(cell differentiation);GO:0031047(gene silencing by RNA);GO:0007283(spermatogenesis);GO:0005739(mitochondrion);GO:0003723(RNA binding);GO:0004004(ATP-dependent RNA helicase activity);GO:0034587(piRNA metabolic process);GO:0043046(DNA methylation involved in gamete generation);GO:0009566(fertilization);GO:0043186(P granule);GO:0006396(RNA processing);GO:0007140(male meiotic nuclear division);GO:0071547(piP-body)","NA","NA","NA","tudor domain containing 9 [Source:HGNC Symbol;Acc:HGNC:20122]",0,0,1,0,1,1,"no","no"]
[155022,0,"chr5","-",57480016,57482809,"ENST00000423391",1,2794,"ENSG00000169067","ACTBL2","GO:0005737(cytoplasm);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0005615(extracellular space);GO:0003674(molecular_function);GO:0008150(biological_process);GO:0070062(extracellular exosome)","NA","NA","NA","actin, beta like 2 [Source:HGNC Symbol;Acc:HGNC:17780]",0,0,1,0,1,1,"no","no"]
[5870,0,"chr1","-",48411487,48472155,"ENST00000471975",5,545,"ENSG00000132122","SPATA6","GO:0042995(cell projection);GO:0005576(extracellular region);GO:0007275(multicellular organism development);GO:0030154(cell differentiation);GO:0007283(spermatogenesis);GO:0032027(myosin light chain binding);GO:0044458(motile cilium assembly);GO:0097224(sperm connecting piece)","NA","NA","NA","spermatogenesis associated 6 [Source:HGNC Symbol;Acc:HGNC:18309]",0,{"v":4.947E-3,"d":"0.00"},"-inf","-inf",1,1,"down","no"]
[27213,0,"chr11","+",18394560,18402891,"ENST00000543445",5,576,"MSTRG.2293","LDHA","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0003824(catalytic activity);GO:0006096(glycolytic process);GO:0005975(carbohydrate metabolic process);GO:0016616(oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor);GO:0005515(protein binding);GO:0019752(carboxylic acid metabolic process);GO:0004459(L-lactate dehydrogenase activity);GO:0005829(cytosol);GO:0045296(cadherin binding);GO:0070062(extracellular exosome);GO:0006090(pyruvate metabolic process);GO:0016021(integral component of membrane);GO:0004457(lactate dehydrogenase activity);GO:0019900(kinase binding);GO:0042802(identical protein binding);GO:0051287(NAD binding);GO:0001666(response to hypoxia);GO:0006089(lactate metabolic process);GO:0007584(response to nutrient);GO:0009749(response to glucose);GO:0014070(response to organic cyclic compound);GO:0019674(NAD metabolic process);GO:0042493(response to drug);GO:0042542(response to hydrogen peroxide);GO:0043065(positive regulation of apoptotic process);GO:0043627(response to estrogen);GO:0048569(post-embryonic animal organ development);GO:0051591(response to cAMP)","00010(Glycolysis / Gluconeogenesis);00620(Pyruvate metabolism);00640(Propanoate metabolism);00270(Cysteine and methionine metabolism);04066(HIF-1 signaling pathway);04922(Glucagon signaling pathway);05230(Central carbon metabolism in cancer)","NA","NA","lactate dehydrogenase A [Source:HGNC Symbol;Acc:HGNC:6535]",{"v":0.198667,"d":"0.20"},{"v":0.313913,"d":"0.31"},{"v":0.632872802336953,"d":"0.63"},{"v":-0.660012525530011,"d":"-0.66"},1,1,"down","no"]
[105643,0,"chr19","+",54906155,54906778,"ENST00000601903",2,547,"MSTRG.8434","NCR1","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005886(plasma membrane);GO:0050776(regulation of immune response);GO:0005887(integral component of plasma membrane);GO:0007165(signal transduction);GO:0030101(natural killer cell activation);GO:0016514(SWI/SNF complex);GO:0005057(signal transducer activity, downstream of receptor);GO:0006968(cellular defense response);GO:0042269(regulation of natural killer cell mediated cytotoxicity)","04650(Natural killer cell mediated cytotoxicity)","NA","NA","natural cytotoxicity triggering receptor 1 [Source:HGNC Symbol;Acc:HGNC:6731]",{"v":0.323115,"d":"0.32"},{"v":0.105269,"d":"0.11"},{"v":3.06942214707084,"d":"3.07"},{"v":1.61796707773755,"d":"1.62"},1,1,"up","no"]
[14372,0,"chr1","+",186451081,186451749,"ENST00000429768",2,314,"ENSG00000229739","AL596220.1","NA","NA","NA","NA","NA",0,{"v":0.028444,"d":"0.03"},"-inf","-inf",1,1,"down","no"]
[53569,0,"chr14","-",24187491,24188069,"ENST00000559635",2,492,"MSTRG.4351","IPO4","GO:0006810(transport);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0006886(intracellular protein transport);GO:0015031(protein transport);GO:0000790(nuclear chromatin);GO:0008536(Ran GTPase binding);GO:0005643(nuclear pore);GO:0005515(protein binding);GO:0043234(protein complex);GO:0008139(nuclear localization sequence binding);GO:0008565(protein transporter activity);GO:0006607(NLS-bearing protein import into nucleus);GO:0000060(protein import into nucleus, translocation);GO:0031965(nuclear membrane);GO:0034399(nuclear periphery);GO:0006610(ribosomal protein import into nucleus);GO:0006335(DNA replication-dependent nucleosome assembly);GO:0006336(DNA replication-independent nucleosome assembly);GO:0005622(intracellular)","NA","NA","NA","importin 4 [Source:HGNC Symbol;Acc:HGNC:19426]",0,0,1,0,1,1,"no","no"]
[95742,0,"chr19","+",7637115,7639485,"ENST00000599905",3,589,"MSTRG.7753","STXBP2","GO:0016192(vesicle-mediated transport);GO:0006904(vesicle docking involved in exocytosis);GO:0005829(cytosol);GO:0006810(transport);GO:0015031(protein transport);GO:0005886(plasma membrane);GO:0005576(extracellular region);GO:0005515(protein binding);GO:0006887(exocytosis);GO:0070062(extracellular exosome);GO:0031201(SNARE complex);GO:0042581(specific granule);GO:0042582(azurophil granule);GO:0043312(neutrophil degranulation);GO:0070820(tertiary granule);GO:0002576(platelet degranulation);GO:0043304(regulation of mast cell degranulation);GO:0044194(cytolytic granule);GO:0017075(syntaxin-1 binding);GO:0030348(syntaxin-3 binding);GO:0001909(leukocyte mediated cytotoxicity);GO:0016324(apical plasma membrane);GO:0042589(zymogen granule membrane);GO:0016020(membrane);GO:0016021(integral component of membrane)","NA","NA","NA","syntaxin binding protein 2 [Source:HGNC Symbol;Acc:HGNC:11445]",{"v":0.10559,"d":"0.11"},{"v":0.053177,"d":"0.05"},{"v":1.98563288639825,"d":"1.99"},{"v":0.989598914945722,"d":"0.99"},1,1,"up","no"]
[190811,0,"chr9","+",66900738,66921426,"ENST00000612867",5,4160,"ENSG00000274349","ZNF658","GO:0003676(nucleic acid binding);GO:0046872(metal ion binding);GO:0006355(regulation of transcription, DNA-templated);GO:0005622(intracellular);GO:0005634(nucleus);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0042254(ribosome biogenesis);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0045892(negative regulation of transcription, DNA-templated);GO:0000976(transcription regulatory region sequence-specific DNA binding);GO:0071294(cellular response to zinc ion)","NA","NA","NA","zinc finger protein 658 [Source:HGNC Symbol;Acc:HGNC:25226]",{"v":0.012736,"d":"0.01"},{"v":0.003247,"d":"0.00"},{"v":3.92238989836772,"d":"3.92"},{"v":1.97173295125756,"d":"1.97"},1,1,"up","no"]
[176542,0,"chr7","-",99458195,99460465,"ENST00000491560",3,658,"MSTRG.13796","ATP5J2","GO:0006810(transport);GO:0005634(nucleus);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005654(nucleoplasm);GO:0005739(mitochondrion);GO:0005743(mitochondrial inner membrane);GO:0006811(ion transport);GO:0015992(proton transport);GO:0070062(extracellular exosome);GO:0016887(ATPase activity);GO:0006754(ATP biosynthetic process);GO:0022857(transmembrane transporter activity);GO:0042407(cristae formation);GO:0042776(mitochondrial ATP synthesis coupled proton transport);GO:0005753(mitochondrial proton-transporting ATP synthase complex);GO:0045263(proton-transporting ATP synthase complex, coupling factor F(o));GO:0046034(ATP metabolic process);GO:0000276(mitochondrial proton-transporting ATP synthase complex, coupling factor F(o))","00190(Oxidative phosphorylation)","NA","NA","ATP synthase, H+ transporting, mitochondrial Fo complex subunit F2 [Source:HGNC Symbol;Acc:HGNC:848]",{"v":0.607926,"d":"0.61"},{"v":1.64259,"d":"1.64"},{"v":0.370102094862382,"d":"0.37"},{"v":-1.4340047932427,"d":"-1.43"},1,1,"down","no"]
[155263,0,"chr5","+",65563239,65587541,"ENST00000535264",12,2195,"MSTRG.12086","PPWD1","GO:0006397(mRNA processing);GO:0008380(RNA splicing);GO:0005634(nucleus);GO:0016853(isomerase activity);GO:0003755(peptidyl-prolyl cis-trans isomerase activity);GO:0000413(protein peptidyl-prolyl isomerization);GO:0006457(protein folding);GO:0005681(spliceosomal complex);GO:0016604(nuclear body);GO:0005654(nucleoplasm);GO:0000398(mRNA splicing, via spliceosome);GO:0071013(catalytic step 2 spliceosome)","NA","NA","NA","peptidylprolyl isomerase domain and WD repeat containing 1 [Source:HGNC Symbol;Acc:HGNC:28954]",0,{"v":4.8e-05,"d":"0.00"},"-inf","-inf",1,1,"down","no"]
[188855,0,"chr9","-",4646299,4666307,"ENST00000471669",4,513,"ENSG00000106686","SPATA6L","NA","NA","NA","NA","spermatogenesis associated 6 like [Source:HGNC Symbol;Acc:HGNC:25472]",0,0,1,0,1,1,"no","no"]
[162029,0,"chr5","+",179823565,179824314,"ENST00000485412",2,656,"MSTRG.12609","SQSTM1","GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0043231(intracellular membrane-bounded organelle);GO:0004674(protein serine/threonine kinase activity);GO:0005829(cytosol);GO:0006468(protein phosphorylation);GO:0005783(endoplasmic reticulum);GO:0005515(protein binding);GO:0006915(apoptotic process);GO:0030154(cell differentiation);GO:0006914(autophagy);GO:0031410(cytoplasmic vesicle);GO:0002376(immune system process);GO:0005764(lysosome);GO:0042802(identical protein binding);GO:0000932(P-body);GO:0005768(endosome);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0005654(nucleoplasm);GO:0070062(extracellular exosome);GO:0019901(protein kinase binding);GO:0061635(regulation of protein complex stability);GO:0042169(SH2 domain binding);GO:0031625(ubiquitin protein ligase binding);GO:0016197(endosomal transport);GO:0005770(late endosome);GO:0005776(autophagosome);GO:0043130(ubiquitin binding);GO:0019899(enzyme binding);GO:0016605(PML body);GO:0035556(intracellular signal transduction);GO:0016236(macroautophagy);GO:0043065(positive regulation of apoptotic process);GO:0043066(negative regulation of apoptotic process);GO:0006950(response to stress);GO:0043122(regulation of I-kappaB kinase/NF-kappaB signaling);GO:0006511(ubiquitin-dependent protein catabolic process);GO:0008104(protein localization);GO:0010821(regulation of mitochondrion organization);GO:0007032(endosome organization);GO:0000422(mitophagy);GO:0005080(protein kinase C binding);GO:0016234(inclusion body);GO:0046578(regulation of Ras protein signal transduction);GO:0030971(receptor tyrosine kinase binding);GO:0042803(protein homodimerization activity);GO:0070530(K63-linked polyubiquitin binding);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0000423(macromitophagy);GO:0001934(positive regulation of protein phosphorylation);GO:0044130(negative regulation of growth of symbiont in host);GO:0051291(protein heterooligomerization);GO:0098780(response to mitochondrial depolarisation);GO:1905719(protein localization to perinuclear region of cytoplasm);GO:0000407(pre-autophagosomal structure);GO:0016235(aggresome);GO:0044753(amphisome);GO:0044754(autolysosome);GO:0097225(sperm midpiece)","04137(Mitophagy - animal);04217(Necroptosis);04218(Cellular senescence);04380(Osteoclast differentiation);05418(Fluid shear stress and atherosclerosis)","NA","NA","sequestosome 1 [Source:HGNC Symbol;Acc:HGNC:11280]",{"v":0.087148,"d":"0.09"},{"v":0.157187,"d":"0.16"},{"v":0.554422439514718,"d":"0.55"},{"v":-0.85094244505751,"d":"-0.85"},1,1,"down","no"]
[55176,0,"chr14","+",54754833,54789127,"ENST00000555192",9,1337,"ENSG00000020577","SAMD4A","GO:0003723(RNA binding);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0006355(regulation of transcription, DNA-templated);GO:0001650(fibrillar center);GO:0030054(cell junction);GO:0042995(cell projection);GO:0005515(protein binding);GO:0045202(synapse);GO:0030425(dendrite);GO:0006417(regulation of translation);GO:0003729(mRNA binding);GO:0000932(P-body);GO:0043005(neuron projection);GO:0017148(negative regulation of translation);GO:0045727(positive regulation of translation);GO:0000289(nuclear-transcribed mRNA poly(A) tail shortening);GO:0043488(regulation of mRNA stability);GO:0030371(translation repressor activity)","NA","NA","NA","sterile alpha motif domain containing 4A [Source:HGNC Symbol;Acc:HGNC:23023]",0,0,1,0,1,1,"no","no"]
[29686,0,"chr11","+",60280685,60302644,"ENST00000529950",6,658,"ENSG00000110079","MS4A4A","GO:0016020(membrane);GO:0016021(integral component of membrane)","NA","NA","NA","membrane spanning 4-domains A4A [Source:HGNC Symbol;Acc:HGNC:13371]",0,0,1,0,1,1,"no","no"]
[93338,0,"chr18","-",70060035,70139607,"ENST00000640931",17,2065,"ENSG00000176225","RTTN","GO:0005813(centrosome);GO:0036064(ciliary basal body);GO:0044782(cilium organization);GO:0005737(cytoplasm);GO:0005856(cytoskeleton);GO:0042995(cell projection);GO:0007275(multicellular organism development);GO:0005929(cilium);GO:0007368(determination of left/right symmetry);GO:0016020(membrane);GO:0016021(integral component of membrane)","NA","NA","NA","rotatin [Source:HGNC Symbol;Acc:HGNC:18654]",0,0,1,0,1,1,"no","no"]
[121051,0,"chr2","-",241230204,241231343,"ENST00000488013",2,651,"MSTRG.9532","HDLBP","GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0005829(cytosol);GO:0006810(transport);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0006629(lipid metabolic process);GO:0008202(steroid metabolic process);GO:0005515(protein binding);GO:0006869(lipid transport);GO:0008203(cholesterol metabolic process);GO:0005886(plasma membrane);GO:0045296(cadherin binding);GO:0034364(high-density lipoprotein particle);GO:0008289(lipid binding);GO:0034384(high-density lipoprotein particle clearance)","NA","NA","NA","high density lipoprotein binding protein [Source:HGNC Symbol;Acc:HGNC:4857]",{"v":0.071717,"d":"0.07"},{"v":0.007733,"d":"0.01"},{"v":9.27414974783396,"d":"9.27"},{"v":3.21321502180768,"d":"3.21"},1,1,"up","no"]
[98559,0,"chr19","-",18309751,18316259,"ENST00000597776",3,446,"MSTRG.7988","LSM4","GO:0003723(RNA binding);GO:0006396(RNA processing);GO:0006397(mRNA processing);GO:0008380(RNA splicing);GO:0005634(nucleus);GO:0030529(intracellular ribonucleoprotein complex);GO:0005515(protein binding);GO:0005681(spliceosomal complex);GO:0000398(mRNA splicing, via spliceosome);GO:0000956(nuclear-transcribed mRNA catabolic process);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0033962(cytoplasmic mRNA processing body assembly);GO:0000932(P-body);GO:0043234(protein complex);GO:0043928(exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay);GO:0017070(U6 snRNA binding);GO:0000245(spliceosomal complex assembly);GO:0016020(membrane);GO:0097526(spliceosomal tri-snRNP complex);GO:0000387(spliceosomal snRNP assembly);GO:0042731(PH domain binding);GO:0005688(U6 snRNP);GO:0043005(neuron projection)","03040(Spliceosome);03018(RNA degradation)","NA","NA","LSM4 homolog, U6 small nuclear RNA and mRNA degradation associated [Source:HGNC Symbol;Acc:HGNC:17259]",{"v":0.643111,"d":"0.64"},{"v":0.432576,"d":"0.43"},{"v":1.48670060289984,"d":"1.49"},{"v":0.572114141538667,"d":"0.57"},1,1,"up","no"]
[32293,0,"chr11","-",68891276,68903786,"ENST00000450904",7,662,"MSTRG.2635","MRPL21","GO:0005840(ribosome);GO:0003723(RNA binding);GO:0030529(intracellular ribonucleoprotein complex);GO:0005622(intracellular);GO:0003735(structural constituent of ribosome);GO:0006412(translation);GO:0005739(mitochondrion);GO:0005743(mitochondrial inner membrane);GO:0070125(mitochondrial translational elongation);GO:0070126(mitochondrial translational termination);GO:0005762(mitochondrial large ribosomal subunit)","03010(Ribosome)","K02888","NA","mitochondrial ribosomal protein L21 [Source:HGNC Symbol;Acc:HGNC:14479]",{"v":0.213434,"d":"0.21"},{"v":0.254159,"d":"0.25"},{"v":0.839765658505109,"d":"0.84"},{"v":-0.251941303281946,"d":"-0.25"},1,1,"down","no"]
[159875,0,"chr5","-",149025778,149063047,"ENST00000513604",12,4051,"ENSG00000169247","SH3TC2","GO:0022011(myelination in peripheral nervous system);GO:0032287(peripheral nervous system myelin maintenance);GO:0033157(regulation of intracellular protein transport);GO:1901184(regulation of ERBB signaling pathway);GO:0005886(plasma membrane);GO:0031410(cytoplasmic vesicle);GO:0055037(recycling endosome)","NA","NA","NA","SH3 domain and tetratricopeptide repeats 2 [Source:HGNC Symbol;Acc:HGNC:29427]",{"v":0.083492,"d":"0.08"},{"v":0.031007,"d":"0.03"},{"v":2.69268229754572,"d":"2.69"},{"v":1.42904402011295,"d":"1.43"},1,1,"up","no"]
[114559,0,"chr2","-",131442644,131444587,"ENST00000407594",1,1944,"ENSG00000217950","NOC2LP2","NA","NA","NA","NA","NOC2 like nucleolar associated transcriptional repressor pseudogene 2 [Source:HGNC Symbol;Acc:HGNC:52286]",0,0,1,0,1,1,"no","no"]
[17053,0,"chr1","-",232984136,233200191,"ENST00000462233",20,3392,"ENSG00000135749","PCNX2","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0003674(molecular_function);GO:0008150(biological_process);GO:0005575(cellular_component)","NA","NA","NA","pecanex homolog 2 [Source:HGNC Symbol;Acc:HGNC:8736]",0,{"v":0.540977,"d":"0.54"},"-inf","-inf",1,1,"down","no"]
[154406,0,"chr5","-",39718984,39721513,"ENST00000504674",1,2530,"ENSG00000250492","INTS6P1","NA","NA","NA","NA","integrator complex subunit 6 pseudogene 1 [Source:HGNC Symbol;Acc:HGNC:43921]",0,0,1,0,1,1,"no","no"]
[172595,0,"chr7","+",27120937,27122650,"ENST00000523364",2,989,"ENSG00000253552","HOXA-AS2","NA","NA","NA","NA","HOXA cluster antisense RNA 2 [Source:HGNC Symbol;Acc:HGNC:43745]",0,0,1,0,1,1,"no","no"]
[40543,0,"chr12","-",43729258,43758773,"ENST00000551923",9,3313,"MSTRG.3290","PUS7L","GO:0003723(RNA binding);GO:0009982(pseudouridine synthase activity);GO:0001522(pseudouridine synthesis);GO:0009451(RNA modification);GO:0016853(isomerase activity);GO:0008033(tRNA processing);GO:0005515(protein binding)","NA","NA","NA","pseudouridylate synthase 7 like [Source:HGNC Symbol;Acc:HGNC:25276]",{"v":0.221087,"d":"0.22"},{"v":0.138778,"d":"0.14"},{"v":1.59309832970644,"d":"1.59"},{"v":0.671835316079672,"d":"0.67"},1,1,"up","no"]
[88134,0,"chr17","+",75667366,75691890,"ENST00000578288",5,870,"MSTRG.7222","SAP30BP","GO:0006355(regulation of transcription, DNA-templated);GO:0005654(nucleoplasm);GO:0045111(intermediate filament cytoskeleton);GO:0005634(nucleus);GO:0006351(transcription, DNA-templated);GO:0005515(protein binding);GO:0006915(apoptotic process);GO:0010942(positive regulation of cell death)","NA","NA","NA","SAP30 binding protein [Source:HGNC Symbol;Acc:HGNC:30785]",{"v":0.343636,"d":"0.34"},0,"inf","inf",1,1,"up","no"]
[102795,0,"chr19","-",45485649,45488569,"ENST00000593187",3,299,"ENSG00000125744","RTN2","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005515(protein binding);GO:0030176(integral component of endoplasmic reticulum membrane);GO:0046324(regulation of glucose import);GO:0065002(intracellular protein transmembrane transport);GO:0014802(terminal cisterna);GO:0030315(T-tubule)","NA","NA","NA","reticulon 2 [Source:HGNC Symbol;Acc:HGNC:10468]",0,{"v":0.417964,"d":"0.42"},"-inf","-inf",1,1,"down","no"]
[169790,0,"chr6","+",143060899,143190597,"ENST00000629020",4,3636,"ENSG00000146416","AIG1","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005515(protein binding);GO:0012505(endomembrane system)","NA","NA","NA","androgen induced 1 [Source:HGNC Symbol;Acc:HGNC:21607]",{"v":0.012135,"d":"0.01"},{"v":0.696264,"d":"0.70"},{"v":0.0174287339285099,"d":"0.02"},{"v":-5.84238841786716,"d":"-5.84"},1,1,"down","no"]
[186632,0,"chr8","-",116655905,116755822,"ENST00000518995",6,731,"MSTRG.14526","EIF3H","GO:0003723(RNA binding);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0003743(translation initiation factor activity);GO:0001731(formation of translation preinitiation complex);GO:0006412(translation);GO:0006413(translational initiation);GO:0006446(regulation of translational initiation);GO:0005852(eukaryotic translation initiation factor 3 complex);GO:0016282(eukaryotic 43S preinitiation complex);GO:0033290(eukaryotic 48S preinitiation complex);GO:0005515(protein binding);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0071541(eukaryotic translation initiation factor 3 complex, eIF3m)","03013(RNA transport);05162(Measles)","NA","NA","eukaryotic translation initiation factor 3 subunit H [Source:HGNC Symbol;Acc:HGNC:3273]",{"v":0.000719,"d":"0.00"},{"v":0.303574,"d":"0.30"},{"v":0.00236845052606613,"d":"0.00"},{"v":-8.7218407485015,"d":"-8.72"},1,1,"down","no"]
[146948,0,"chr4","-",40438242,40630316,"ENST00000515053",4,1100,"MSTRG.11588","RBM47","GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0005634(nucleus);GO:0002244(hematopoietic progenitor cell differentiation);GO:0016554(cytidine to uridine editing)","NA","NA","NA","RNA binding motif protein 47 [Source:HGNC Symbol;Acc:HGNC:30358]",{"v":0.007745,"d":"0.01"},{"v":8e-05,"d":"0.00"},{"v":96.8125,"d":"96.81"},{"v":6.59712142878957,"d":"6.60"},1,1,"up","no"]
[131481,0,"chr22","+",39379610,39380015,"ENST00000623458",1,406,"ENSG00000280216","AL022326.2","NA","NA","NA","NA","NA",0,0,1,0,1,1,"no","no"]
[34729,0,"chr11","+",105610073,105982092,"ENST00000393127",17,5621,"ENSG00000152578","GRIA4","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005216(ion channel activity);GO:0006811(ion transport);GO:0034220(ion transmembrane transport);GO:0005886(plasma membrane);GO:0042995(cell projection);GO:0030054(cell junction);GO:0045202(synapse);GO:0045211(postsynaptic membrane);GO:0004872(receptor activity);GO:0030425(dendrite);GO:0004970(ionotropic glutamate receptor activity);GO:0005234(extracellular-glutamate-gated ion channel activity);GO:0035235(ionotropic glutamate receptor signaling pathway);GO:0060079(excitatory postsynaptic potential);GO:0032281(AMPA glutamate receptor complex);GO:0030666(endocytic vesicle membrane);GO:1903561(extracellular vesicle);GO:0007215(glutamate receptor signaling pathway);GO:0004971(AMPA glutamate receptor activity);GO:0005231(excitatory extracellular ligand-gated ion channel activity)","04024(cAMP signaling pathway);04080(Neuroactive ligand-receptor interaction);04724(Glutamatergic synapse);04728(Dopaminergic synapse);04723(Retrograde endocannabinoid signaling);04713(Circadian entrainment);05031(Amphetamine addiction);05033(Nicotine addiction)","K05200","NA","glutamate ionotropic receptor AMPA type subunit 4 [Source:HGNC Symbol;Acc:HGNC:4574]",0,{"v":0.007529,"d":"0.01"},"-inf","-inf",1,1,"down","no"]
[200958,0,"chrX","+",153776412,153785728,"ENST00000489426",21,4479,"MSTRG.15489","SRPK3","GO:0004672(protein kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0000166(nucleotide binding);GO:0004674(protein serine/threonine kinase activity);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0005515(protein binding);GO:0007275(multicellular organism development);GO:0030154(cell differentiation);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0035556(intracellular signal transduction);GO:0005575(cellular_component);GO:0007517(muscle organ development);GO:0000245(spliceosomal complex assembly);GO:0050684(regulation of mRNA processing);GO:0060537(muscle tissue development);GO:0007519(skeletal muscle tissue development)","NA","NA","NA","SRSF protein kinase 3 [Source:HGNC Symbol;Acc:HGNC:11402]",{"v":0.010467,"d":"0.01"},{"v":0.044564,"d":"0.04"},{"v":0.23487568440894,"d":"0.23"},{"v":-2.09003072933806,"d":"-2.09"},1,1,"down","no"]
[178821,0,"chr7","+",131110140,131399384,"ENST00000416992",8,864,"MSTRG.13970","MKLN1","GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0042995(cell projection);GO:0005938(cell cortex);GO:0008360(regulation of cell shape);GO:0001726(ruffle);GO:0007165(signal transduction);GO:0007160(cell-matrix adhesion);GO:0031532(actin cytoskeleton reorganization)","NA","NA","NA","muskelin 1 [Source:HGNC Symbol;Acc:HGNC:7109]",0,0,1,0,1,1,"no","no"]
[201253,0,"chrX","+",154436913,154439765,"ENST00000630693",5,786,"MSTRG.15509","GDI1","GO:0005737(cytoplasm);GO:0015031(protein transport);GO:0007264(small GTPase mediated signal transduction);GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0005794(Golgi apparatus);GO:0050790(regulation of catalytic activity);GO:0043547(positive regulation of GTPase activity);GO:0005515(protein binding);GO:0005096(GTPase activator activity);GO:0005092(GDP-dissociation inhibitor activity);GO:0030496(midbody);GO:0005093(Rab GDP-dissociation inhibitor activity);GO:0017137(Rab GTPase binding);GO:0050771(negative regulation of axonogenesis);GO:0051592(response to calcium ion);GO:0043005(neuron projection);GO:0043209(myelin sheath);GO:0043234(protein complex);GO:0005829(cytosol);GO:0051056(regulation of small GTPase mediated signal transduction);GO:0061024(membrane organization);GO:0007165(signal transduction);GO:0090315(negative regulation of protein targeting to membrane);GO:0032482(Rab protein signal transduction);GO:0005622(intracellular)","NA","NA","NA","GDP dissociation inhibitor 1 [Source:HGNC Symbol;Acc:HGNC:4226]",{"v":0.020631,"d":"0.02"},0,"inf","inf",1,1,"up","no"]
[197583,0,"chrX","-",54173789,54183281,"ENST00000477084",2,1140,"ENSG00000184083","FAM120C","GO:0005634(nucleus);GO:0003723(RNA binding)","NA","NA","NA","family with sequence similarity 120C [Source:HGNC Symbol;Acc:HGNC:16949]",{"v":0.840788,"d":"0.84"},{"v":0.019512,"d":"0.02"},{"v":43.0908159081591,"d":"43.09"},{"v":5.42930851047446,"d":"5.43"},1,1,"up","no"]
[48390,0,"chr12","-",128808806,128823522,"ENST00000376740",5,761,"MSTRG.3868","SLC15A4","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0015031(protein transport);GO:0005215(transporter activity);GO:0015293(symporter activity);GO:0055085(transmembrane transport);GO:0005886(plasma membrane);GO:0015992(proton transport);GO:0015833(peptide transport);GO:0006857(oligopeptide transport);GO:0043312(neutrophil degranulation);GO:0035579(specific granule membrane);GO:0006811(ion transport);GO:0005765(lysosomal membrane);GO:0015333(peptide:proton symporter activity)","NA","NA","NA","solute carrier family 15 member 4 [Source:HGNC Symbol;Acc:HGNC:23090]",{"v":0.92253,"d":"0.92"},{"v":0.443727,"d":"0.44"},{"v":2.07904860420935,"d":"2.08"},{"v":1.05592348606167,"d":"1.06"},1,1,"up","no"]
[57657,0,"chr14","+",90398262,90405107,"ENST00000544280",6,1064,"MSTRG.4607","CALM1","GO:0005509(calcium ion binding);GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0000922(spindle pole);GO:0005819(spindle);GO:0044325(ion channel binding);GO:0090150(establishment of protein localization to membrane);GO:0090151(establishment of protein localization to mitochondrial membrane);GO:1900242(regulation of synaptic vesicle endocytosis);GO:2000300(regulation of synaptic vesicle exocytosis);GO:0014069(postsynaptic density);GO:0030672(synaptic vesicle membrane);GO:0031966(mitochondrial membrane);GO:0043209(myelin sheath);GO:0019855(calcium channel inhibitor activity);GO:0060315(negative regulation of ryanodine-sensitive calcium-release channel activity)","04014(Ras signaling pathway);04015(Rap1 signaling pathway);04371(Apelin signaling pathway);04020(Calcium signaling pathway);04070(Phosphatidylinositol signaling system);04024(cAMP signaling pathway);04022(cGMP - PKG signaling pathway);04114(Oocyte meiosis);04218(Cellular senescence);04910(Insulin signaling pathway);04922(Glucagon signaling pathway);04912(GnRH signaling pathway);04915(Estrogen signaling pathway);04921(Oxytocin signaling pathway);04916(Melanogenesis);04924(Renin secretion);04925(Aldosterone synthesis and secretion);04261(Adrenergic signaling in cardiomyocytes);04270(Vascular smooth muscle contraction);04970(Salivary secretion);04971(Gastric acid secretion);04728(Dopaminergic synapse);04720(Long-term potentiation);04722(Neurotrophin signaling pathway);04744(Phototransduction);04740(Olfactory transduction);04750(Inflammatory mediator regulation of TRP channels);04713(Circadian entrainment);05200(Pathways in cancer);05214(Glioma);05010(Alzheimer's disease);05031(Amphetamine addiction);05034(Alcoholism);05418(Fluid shear stress and atherosclerosis);05133(Pertussis);05152(Tuberculosis);05167(Kaposi's sarcoma-associated herpesvirus infection)","NA","NA","calmodulin 1 [Source:HGNC Symbol;Acc:HGNC:1442]",{"v":0.442123,"d":"0.44"},{"v":0.393576,"d":"0.39"},{"v":1.12334847653312,"d":"1.12"},{"v":0.167805538939969,"d":"0.17"},1,1,"up","no"]
[163685,0,"chr6","-",28431930,28443480,"ENST00000481983",4,1316,"ENSG00000187987","ZSCAN23","GO:0005634(nucleus);GO:0006355(regulation of transcription, DNA-templated);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0003676(nucleic acid binding);GO:0046872(metal ion binding);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0070062(extracellular exosome)","NA","NA","NA","zinc finger and SCAN domain containing 23 [Source:HGNC Symbol;Acc:HGNC:21193]",{"v":0.164235,"d":"0.16"},0,"inf","inf",1,1,"up","no"]
[28640,0,"chr11","+",46936697,47161911,"ENST00000528488",10,1623,"MSTRG.2363","C11orf49","GO:0005515(protein binding)","NA","NA","NA","chromosome 11 open reading frame 49 [Source:HGNC Symbol;Acc:HGNC:28720]",0,0,1,0,1,1,"no","no"]
[72640,0,"chr16","-",46673443,46673927,"ENST00000623850",1,485,"MSTRG.5904","AC012186.3","NA","NA","NA","NA","NA",0,0,1,0,1,1,"no","no"]
[144676,0,"chr3","-",196708859,196708964,"ENST00000364571",1,106,"MSTRG.11459","RNU6-646P","NA","NA","NA","NA","RNA, U6 small nuclear 646, pseudogene [Source:HGNC Symbol;Acc:HGNC:47609]",{"v":0.322953,"d":"0.32"},{"v":0.323676,"d":"0.32"},{"v":0.997766284803322,"d":"1.00"},{"v":-0.0032261743572628,"d":"-0.00"},1,1,"down","no"]
[126415,0,"chr21","+",29077496,29102640,"ENST00000492930",6,769,"MSTRG.9975","MAP3K7CL","GO:0005634(nucleus);GO:0000165(MAPK cascade);GO:0005829(cytosol);GO:0005515(protein binding);GO:0004709(MAP kinase kinase kinase activity);GO:0000186(activation of MAPKK activity)","NA","NA","NA","MAP3K7 C-terminal like [Source:HGNC Symbol;Acc:HGNC:16457]",{"v":0.211889,"d":"0.21"},{"v":0.295355,"d":"0.30"},{"v":0.717404479355352,"d":"0.72"},{"v":-0.479141341613701,"d":"-0.48"},1,1,"down","no"]
[65261,0,"chr15","+",78149380,78168966,"ENST00000559803",10,1008,"ENSG00000166411","IDH3A","GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0000287(magnesium ion binding);GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0006099(tricarboxylic acid cycle);GO:0005739(mitochondrion);GO:0016616(oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor);GO:0051287(NAD binding);GO:0004449(isocitrate dehydrogenase (NAD+) activity);GO:0005759(mitochondrial matrix);GO:0005975(carbohydrate metabolic process);GO:0043209(myelin sheath)","00020(Citrate cycle (TCA cycle))","NA","NA","isocitrate dehydrogenase 3 (NAD(+)) alpha [Source:HGNC Symbol;Acc:HGNC:5384]",0,{"v":0.284037,"d":"0.28"},"-inf","-inf",1,1,"down","no"]
[199899,0,"chrX","-",129805329,129843460,"ENST00000371064",10,2473,"ENSG00000188706","ZDHHC9","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005794(Golgi apparatus);GO:0005829(cytosol);GO:0016740(transferase activity);GO:0016746(transferase activity, transferring acyl groups);GO:0019706(protein-cysteine S-palmitoyltransferase activity);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005515(protein binding);GO:0000139(Golgi membrane);GO:0016409(palmitoyltransferase activity);GO:0018345(protein palmitoylation);GO:0018230(peptidyl-L-cysteine S-palmitoylation);GO:0002178(palmitoyltransferase complex);GO:0031228(intrinsic component of Golgi membrane);GO:0043849(Ras palmitoyltransferase activity)","NA","NA","NA","zinc finger DHHC-type containing 9 [Source:HGNC Symbol;Acc:HGNC:18475]",{"v":0.094882,"d":"0.09"},0,"inf","inf",1,1,"up","no"]
[153558,0,"chr5","+",14183798,14399400,"ENST00000509967",30,4949,"ENSG00000038382","TRIO","GO:0005737(cytoplasm);GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0005089(Rho guanyl-nucleotide exchange factor activity);GO:0035023(regulation of Rho protein signal transduction);GO:0043547(positive regulation of GTPase activity);GO:0005515(protein binding);GO:0005085(guanyl-nucleotide exchange factor activity);GO:0005829(cytosol);GO:0051056(regulation of small GTPase mediated signal transduction);GO:0043065(positive regulation of apoptotic process);GO:0019899(enzyme binding);GO:0007185(transmembrane receptor protein tyrosine phosphatase signaling pathway)","NA","NA","NA","trio Rho guanine nucleotide exchange factor [Source:HGNC Symbol;Acc:HGNC:12303]",{"v":0.012152,"d":"0.01"},{"v":0.466023,"d":"0.47"},{"v":0.0260759662076764,"d":"0.03"},{"v":-5.26113547903553,"d":"-5.26"},1,1,"down","no"]
[68496,"j","chr16","+",2752421,2771412,"MSTRG.5569.2",14,9550,"MSTRG.5569","SRRM2","NA","NA","NA","NA","NA",{"v":6.083386,"d":"6.08"},0,"inf","inf",1,1,"up","no"]
[106886,0,"chr2","-",3188925,3320544,"ENST00000478754",11,2932,"ENSG00000032389","EIPR1","NA","NA","NA","NA","EARP complex and GARP complex interacting protein 1 [Source:HGNC Symbol;Acc:HGNC:12383]",0,{"v":0.016887,"d":"0.02"},"-inf","-inf",1,1,"down","no"]
[143479,0,"chr3","+",184314502,184335353,"ENST00000414031",33,5569,"MSTRG.11394","EIF4G1","GO:0003723(RNA binding);GO:0016020(membrane);GO:0003743(translation initiation factor activity);GO:0006412(translation);GO:0006413(translational initiation);GO:0006446(regulation of translational initiation);GO:0005515(protein binding);GO:0008190(eukaryotic initiation factor 4E binding);GO:0005829(cytosol);GO:0045296(cadherin binding);GO:0043488(regulation of mRNA stability);GO:0000289(nuclear-transcribed mRNA poly(A) tail shortening);GO:0006417(regulation of translation);GO:0016032(viral process);GO:0010507(negative regulation of autophagy);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0008135(translation factor activity, RNA binding);GO:0007005(mitochondrion organization);GO:0005524(ATP binding);GO:0000184(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay);GO:0016281(eukaryotic translation initiation factor 4F complex);GO:1901215(negative regulation of neuron death);GO:0033138(positive regulation of peptidyl-serine phosphorylation);GO:0008284(positive regulation of cell proliferation);GO:1905606(regulation of presynapse assembly);GO:0010801(negative regulation of peptidyl-threonine phosphorylation);GO:0030307(positive regulation of cell growth);GO:0034645(cellular macromolecule biosynthetic process);GO:0022627(cytosolic small ribosomal subunit);GO:0003729(mRNA binding);GO:0031369(translation initiation factor binding);GO:0032947(protein complex scaffold);GO:0002191(cap-dependent translational initiation);GO:0032270(positive regulation of cellular protein metabolic process);GO:0032502(developmental process);GO:0060964(regulation of gene silencing by miRNA);GO:0080135(regulation of cellular response to stress);GO:1900087(positive regulation of G1/S transition of mitotic cell cycle);GO:1905537(positive regulation of eukaryotic translation initiation factor 4F complex assembly);GO:1905612(positive regulation of mRNA cap binding);GO:1905618(positive regulation of miRNA mediated inhibition of translation);GO:1905696(regulation of polysome binding);GO:2000507(positive regulation of energy homeostasis);GO:0005844(polysome);GO:0001662(behavioral fear response);GO:0045666(positive regulation of neuron differentiation)","03013(RNA transport);05416(Viral myocarditis)","K03260","NA","eukaryotic translation initiation factor 4 gamma 1 [Source:HGNC Symbol;Acc:HGNC:3296]",0,0,1,0,1,1,"no","no"]
[108233,0,"chr2","+",27370615,27371644,"ENST00000484886",2,568,"MSTRG.8587","SNX17","GO:0006810(transport);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0015031(protein transport);GO:0043231(intracellular membrane-bounded organelle);GO:0005829(cytosol);GO:0007165(signal transduction);GO:0005794(Golgi apparatus);GO:0005515(protein binding);GO:0030659(cytoplasmic vesicle membrane);GO:0031410(cytoplasmic vesicle);GO:0035091(phosphatidylinositol binding);GO:0006886(intracellular protein transport);GO:0008289(lipid binding);GO:0005768(endosome);GO:0005769(early endosome);GO:0016197(endosomal transport);GO:0043234(protein complex);GO:0005102(receptor binding);GO:0008022(protein C-terminus binding);GO:0030100(regulation of endocytosis);GO:0010008(endosome membrane);GO:0006707(cholesterol catabolic process);GO:0050750(low-density lipoprotein particle receptor binding);GO:0003279(cardiac septum development);GO:0006898(receptor-mediated endocytosis);GO:0035904(aorta development);GO:0060976(coronary vasculature development);GO:1990126(retrograde transport, endosome to plasma membrane)","NA","NA","NA","sorting nexin 17 [Source:HGNC Symbol;Acc:HGNC:14979]",{"v":0.352211,"d":"0.35"},{"v":0.512402,"d":"0.51"},{"v":0.687372414627577,"d":"0.69"},{"v":-0.54083613971272,"d":"-0.54"},1,1,"down","no"]
[22565,0,"chr10","-",96620877,96621707,"ENST00000456516",1,831,"MSTRG.1879","RPS2P36","NA","NA","NA","NA","ribosomal protein S2 pseudogene 36 [Source:HGNC Symbol;Acc:HGNC:36784]",{"v":0.383537,"d":"0.38"},0,"inf","inf",1,1,"up","no"]
[123625,0,"chr20","+",38083896,38090259,"ENST00000471511",2,571,"MSTRG.9735","RPRD1B","GO:0005634(nucleus);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0005813(centrosome);GO:0005515(protein binding);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0008284(positive regulation of cell proliferation);GO:0042795(snRNA transcription from RNA polymerase II promoter);GO:0000993(RNA polymerase II core binding);GO:0016591(DNA-directed RNA polymerase II, holoenzyme);GO:0010564(regulation of cell cycle process);GO:0070940(dephosphorylation of RNA polymerase II C-terminal domain)","NA","NA","NA","regulation of nuclear pre-mRNA domain containing 1B [Source:HGNC Symbol;Acc:HGNC:16209]",0,{"v":0.000148,"d":"0.00"},"-inf","-inf",1,1,"down","no"]
[132575,0,"chr22","-",50525752,50530056,"ENST00000252029",10,1630,"MSTRG.10610","TYMP","GO:0016740(transferase activity);GO:0016757(transferase activity, transferring glycosyl groups);GO:0008083(growth factor activity);GO:0008152(metabolic process);GO:0007275(multicellular organism development);GO:0030154(cell differentiation);GO:0006935(chemotaxis);GO:0016763(transferase activity, transferring pentosyl groups);GO:0004645(phosphorylase activity);GO:0006206(pyrimidine nucleobase metabolic process);GO:0006213(pyrimidine nucleoside metabolic process);GO:0005829(cytosol);GO:0009032(thymidine phosphorylase activity);GO:0016154(pyrimidine-nucleoside phosphorylase activity);GO:0043097(pyrimidine nucleoside salvage);GO:0001525(angiogenesis);GO:0042803(protein homodimerization activity);GO:0046135(pyrimidine nucleoside catabolic process);GO:0000002(mitochondrial genome maintenance);GO:0031641(regulation of myelination);GO:0051969(regulation of transmission of nerve impulse);GO:1905333(regulation of gastric motility)","00240(Pyrimidine metabolism);00983(Drug metabolism - other enzymes);05219(Bladder cancer)","K00758","EC:2.4.2.4","thymidine phosphorylase [Source:HGNC Symbol;Acc:HGNC:3148]",0,0,1,0,1,1,"no","no"]
[163243,0,"chr6","-",24649979,24666591,"ENST00000341060",6,2120,"MSTRG.12708","TDP2","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0005654(nucleoplasm);GO:0016787(hydrolase activity);GO:0090305(nucleic acid phosphodiester bond hydrolysis);GO:0016235(aggresome);GO:0006281(DNA repair);GO:0006974(cellular response to DNA damage stimulus);GO:0016604(nuclear body);GO:0000287(magnesium ion binding);GO:0004518(nuclease activity);GO:0005730(nucleolus);GO:1903507(negative regulation of nucleic acid-templated transcription);GO:0005515(protein binding);GO:0048666(neuron development);GO:0007166(cell surface receptor signaling pathway);GO:0003714(transcription corepressor activity);GO:0016605(PML body);GO:0003697(single-stranded DNA binding);GO:0006302(double-strand break repair);GO:0030145(manganese ion binding);GO:0036317(tyrosyl-RNA phosphodiesterase activity);GO:0070260(5'-tyrosyl-DNA phosphodiesterase activity)","NA","NA","NA","tyrosyl-DNA phosphodiesterase 2 [Source:HGNC Symbol;Acc:HGNC:17768]",{"v":0.17276,"d":"0.17"},{"v":0.045598,"d":"0.05"},{"v":3.78876266502917,"d":"3.79"},{"v":1.92172676964088,"d":"1.92"},1,1,"up","no"]
[74488,0,"chr16","-",67438845,67443407,"ENST00000567170",4,590,"MSTRG.6018","ATP6V0D1","GO:0006810(transport);GO:0016020(membrane);GO:0005765(lysosomal membrane);GO:0006811(ion transport);GO:0006879(cellular iron ion homeostasis);GO:0015078(hydrogen ion transmembrane transporter activity);GO:0015991(ATP hydrolysis coupled proton transport);GO:0015992(proton transport);GO:0033179(proton-transporting V-type ATPase, V0 domain);GO:0005813(centrosome);GO:0005515(protein binding);GO:0060271(cilium assembly);GO:0070062(extracellular exosome);GO:0034220(ion transmembrane transport);GO:0030030(cell projection organization);GO:0010008(endosome membrane);GO:0005769(early endosome);GO:0030670(phagocytic vesicle membrane);GO:0036498(IRE1-mediated unfolded protein response);GO:0008286(insulin receptor signaling pathway);GO:0016241(regulation of macroautophagy);GO:0033572(transferrin transport);GO:0090383(phagosome acidification);GO:0036295(cellular response to increased oxygen levels);GO:0008553(hydrogen-exporting ATPase activity, phosphorylative mechanism);GO:0046961(proton-transporting ATPase activity, rotational mechanism);GO:0032403(protein complex binding);GO:0007034(vacuolar transport);GO:0007035(vacuolar acidification);GO:0007420(brain development);GO:0008021(synaptic vesicle);GO:0016324(apical plasma membrane);GO:0016471(vacuolar proton-transporting V-type ATPase complex);GO:0043005(neuron projection);GO:0043234(protein complex);GO:0043679(axon terminus)","00190(Oxidative phosphorylation);04145(Phagosome);04142(Lysosome);04966(Collecting duct acid secretion);04721(Synaptic vesicle cycle);05203(Viral carcinogenesis);05323(Rheumatoid arthritis);05110(Vibrio cholerae infection);05120(Epithelial cell signaling in Helicobacter pylori infection);05152(Tuberculosis)","NA","NA","ATPase H+ transporting V0 subunit d1 [Source:HGNC Symbol;Acc:HGNC:13724]",{"v":0.823706,"d":"0.82"},{"v":0.557545,"d":"0.56"},{"v":1.47738030114161,"d":"1.48"},{"v":0.563041246514534,"d":"0.56"},1,1,"up","no"]
[43822,0,"chr12","-",62689750,62788484,"ENST00000551519",5,584,"ENSG00000111110","PPM1H","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005654(nucleoplasm);GO:0016787(hydrolase activity);GO:0003824(catalytic activity);GO:0006470(protein dephosphorylation);GO:0004721(phosphoprotein phosphatase activity);GO:0004722(protein serine/threonine phosphatase activity)","NA","NA","NA","protein phosphatase, Mg2+/Mn2+ dependent 1H [Source:HGNC Symbol;Acc:HGNC:18583]",{"v":0.128318,"d":"0.13"},0,"inf","inf",1,1,"up","no"]
[159488,0,"chr5","-",141647884,141651387,"ENST00000519800",8,802,"MSTRG.12412","FCHSD1","GO:0031594(neuromuscular junction);GO:0055037(recycling endosome);GO:0007274(neuromuscular synaptic transmission);GO:0030833(regulation of actin filament polymerization)","NA","NA","NA","FCH and double SH3 domains 1 [Source:HGNC Symbol;Acc:HGNC:25463]",{"v":0.219492,"d":"0.22"},{"v":0.932948,"d":"0.93"},{"v":0.235267131715808,"d":"0.24"},{"v":-2.08762831373361,"d":"-2.09"},1,1,"down","no"]
[143043,0,"chr3","+",180912482,180977155,"ENST00000305586",18,3277,"MSTRG.11368","FXR1","GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005829(cytosol);GO:0042803(protein homodimerization activity);GO:0007275(multicellular organism development);GO:0030154(cell differentiation);GO:0005515(protein binding);GO:0003729(mRNA binding);GO:0007517(muscle organ development);GO:2000637(positive regulation of gene silencing by miRNA);GO:0006915(apoptotic process);GO:0046982(protein heterodimerization activity);GO:0005730(nucleolus);GO:0033592(RNA strand annealing activity);GO:0005844(polysome);GO:0002151(G-quadruplex RNA binding);GO:0003730(mRNA 3'-UTR binding);GO:0017148(negative regulation of translation);GO:0005634(nucleus);GO:0030424(axon);GO:0030425(dendrite);GO:0035770(ribonucleoprotein granule);GO:0043034(costamere);GO:0043197(dendritic spine);GO:0048471(perinuclear region of cytoplasm)","03013(RNA transport)","K15516","NA","FMR1 autosomal homolog 1 [Source:HGNC Symbol;Acc:HGNC:4023]",{"v":0.175034,"d":"0.18"},{"v":0.226648,"d":"0.23"},{"v":0.772272422434789,"d":"0.77"},{"v":-0.372818240700545,"d":"-0.37"},1,1,"down","no"]
[108711,0,"chr2","-",36513255,36513732,"ENST00000609765",1,478,"MSTRG.8620","AC007378.1","NA","NA","NA","NA","NA",{"v":0.111129,"d":"0.11"},0,"inf","inf",1,1,"up","no"]
[110011,0,"chr2","+",61065933,61124280,"ENST00000402291",22,4516,"ENSG00000162929","KIAA1841","GO:0003677(DNA binding)","NA","NA","NA","KIAA1841 [Source:HGNC Symbol;Acc:HGNC:29387]",{"v":0.160557,"d":"0.16"},0,"inf","inf",1,1,"up","no"]
[200663,0,"chrX","-",150766339,150898816,"ENST00000613030",12,3742,"MSTRG.15481","CD99L2","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0007155(cell adhesion);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0030054(cell junction);GO:0005925(focal adhesion)","NA","NA","NA","CD99 molecule like 2 [Source:HGNC Symbol;Acc:HGNC:18237]",0,0,1,0,1,1,"no","no"]
[104100,0,"chr19","+",49800692,49801733,"ENST00000593788",3,611,"MSTRG.8329","AP2A1","GO:0006810(transport);GO:0016020(membrane);GO:0008565(protein transporter activity);GO:0006886(intracellular protein transport);GO:0015031(protein transport);GO:0016192(vesicle-mediated transport);GO:0030117(membrane coat);GO:0030131(clathrin adaptor complex);GO:0005886(plasma membrane);GO:0005905(clathrin-coated pit);GO:0005515(protein binding);GO:0005829(cytosol);GO:0006897(endocytosis);GO:0061024(membrane organization);GO:0060071(Wnt signaling pathway, planar cell polarity pathway);GO:0007018(microtubule-based movement);GO:0019886(antigen processing and presentation of exogenous peptide antigen via MHC class II);GO:0006895(Golgi to endosome transport);GO:0048013(ephrin receptor signaling pathway);GO:0030666(endocytic vesicle membrane);GO:0034383(low-density lipoprotein particle clearance);GO:0036020(endolysosome membrane);GO:0050690(regulation of defense response to virus by virus);GO:0030669(clathrin-coated endocytic vesicle membrane);GO:0019901(protein kinase binding);GO:0035615(clathrin adaptor activity);GO:0032802(low-density lipoprotein particle receptor catabolic process);GO:0072583(clathrin-dependent endocytosis);GO:0030122(AP-2 adaptor complex);GO:0050750(low-density lipoprotein particle receptor binding);GO:1900126(negative regulation of hyaluronan biosynthetic process);GO:0030130(clathrin coat of trans-Golgi network vesicle);GO:0008022(protein C-terminus binding);GO:0032403(protein complex binding);GO:0016323(basolateral plasma membrane);GO:0016324(apical plasma membrane);GO:0032433(filopodium tip);GO:0043234(protein complex)","04144(Endocytosis);04961(Endocrine and other factor-regulated calcium reabsorption);04721(Synaptic vesicle cycle);05016(Huntington's disease)","NA","NA","adaptor related protein complex 2 alpha 1 subunit [Source:HGNC Symbol;Acc:HGNC:561]",{"v":0.6718,"d":"0.67"},{"v":0.224985,"d":"0.22"},{"v":2.98597684290064,"d":"2.99"},{"v":1.57820297700562,"d":"1.58"},1,1,"up","no"]
[96272,0,"chr19","-",10094521,10096131,"ENST00000586910",2,568,"MSTRG.7786","ANGPTL6","GO:0005576(extracellular region);GO:0007275(multicellular organism development);GO:0030154(cell differentiation);GO:0070062(extracellular exosome);GO:0001525(angiogenesis);GO:0030141(secretory granule)","NA","NA","NA","angiopoietin like 6 [Source:HGNC Symbol;Acc:HGNC:23140]",{"v":0.172694,"d":"0.17"},{"v":0.065385,"d":"0.07"},{"v":2.64118681654814,"d":"2.64"},{"v":1.40118634988649,"d":"1.40"},1,1,"up","no"]
[176064,0,"chr7","-",92501768,92503064,"ENST00000496092",2,336,"ENSG00000127980","PEX1","GO:0006810(transport);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0015031(protein transport);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0005829(cytosol);GO:0007031(peroxisome organization);GO:0005515(protein binding);GO:0005777(peroxisome);GO:0006625(protein targeting to peroxisome);GO:0005778(peroxisomal membrane);GO:0042623(ATPase activity, coupled);GO:0070062(extracellular exosome);GO:0008022(protein C-terminus binding);GO:0032403(protein complex binding);GO:0016558(protein import into peroxisome matrix);GO:0060152(microtubule-based peroxisome localization)","04146(Peroxisome)","NA","NA","peroxisomal biogenesis factor 1 [Source:HGNC Symbol;Acc:HGNC:8850]",0,0,1,0,1,1,"no","no"]
[98586,0,"chr19","+",18419624,18431705,"ENST00000601614",7,628,"MSTRG.7995","SSBP4","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0003697(single-stranded DNA binding);GO:0005634(nucleus);GO:0006366(transcription from RNA polymerase II promoter);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:0001077(transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding)","NA","NA","NA","single stranded DNA binding protein 4 [Source:HGNC Symbol;Acc:HGNC:15676]",{"v":0.006349,"d":"0.01"},{"v":0.089411,"d":"0.09"},{"v":0.0710091599467627,"d":"0.07"},{"v":-3.81585105026464,"d":"-3.82"},1,1,"down","no"]
[8786,0,"chr1","-",109279567,109282419,"ENST00000492431",5,1870,"ENSG00000134222","PSRC1","GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0051301(cell division);GO:0005856(cytoskeleton);GO:0007049(cell cycle);GO:0000922(spindle pole);GO:0005819(spindle);GO:0005515(protein binding);GO:0005876(spindle microtubule);GO:0045893(positive regulation of transcription, DNA-templated);GO:0015630(microtubule cytoskeleton);GO:0030308(negative regulation of cell growth);GO:0007080(mitotic metaphase plate congression);GO:0008017(microtubule binding);GO:0045737(positive regulation of cyclin-dependent protein serine/threonine kinase activity);GO:0060236(regulation of mitotic spindle organization);GO:0031116(positive regulation of microtubule polymerization);GO:0001578(microtubule bundle formation);GO:0030496(midbody);GO:0009987(cellular process)","NA","NA","NA","proline and serine rich coiled-coil 1 [Source:HGNC Symbol;Acc:HGNC:24472]",{"v":0.028406,"d":"0.03"},{"v":1.298079,"d":"1.30"},{"v":0.0218831057277716,"d":"0.02"},{"v":-5.51403868472987,"d":"-5.51"},1,1,"down","no"]
[13029,0,"chr1","+",161710289,161714352,"ENST00000470841",3,2903,"MSTRG.1145","FCRLA","GO:0005737(cytoplasm);GO:0030154(cell differentiation)","NA","NA","NA","Fc receptor like A [Source:HGNC Symbol;Acc:HGNC:18504]",{"v":0.036394,"d":"0.04"},{"v":0.01676,"d":"0.02"},{"v":2.17147971360382,"d":"2.17"},{"v":1.11867847491021,"d":"1.12"},1,1,"up","no"]
[175015,0,"chr7","+",74093956,74097189,"ENST00000486361",3,569,"MSTRG.13710","LIMK1","GO:0016607(nuclear speck);GO:0046872(metal ion binding);GO:0004672(protein kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0005829(cytosol);GO:0005737(cytoplasm);GO:0005634(nucleus);GO:0000166(nucleotide binding);GO:0004674(protein serine/threonine kinase activity);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0005515(protein binding);GO:0038096(Fc-gamma receptor signaling pathway involved in phagocytosis);GO:0045773(positive regulation of axon extension);GO:0005794(Golgi apparatus);GO:0004871(signal transducer activity);GO:0043005(neuron projection);GO:0007399(nervous system development);GO:0007165(signal transduction);GO:0007266(Rho protein signal transduction);GO:0030036(actin cytoskeleton organization);GO:0051444(negative regulation of ubiquitin-protein transferase activity);GO:0032233(positive regulation of actin filament bundle assembly);GO:0031072(heat shock protein binding);GO:0046982(protein heterodimerization activity);GO:0051496(positive regulation of stress fiber assembly);GO:0005925(focal adhesion);GO:0016020(membrane)","04810(Regulation of actin cytoskeleton);04666(Fc gamma R-mediated phagocytosis);04360(Axon guidance)","NA","NA","LIM domain kinase 1 [Source:HGNC Symbol;Acc:HGNC:6613]",{"v":0.046678,"d":"0.05"},0,"inf","inf",1,1,"up","no"]
[164811,0,"chr6","-",31969948,31972098,"ENST00000474587",7,1115,"MSTRG.12928","DXO","GO:0003723(RNA binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0005829(cytosol);GO:0016787(hydrolase activity);GO:0005886(plasma membrane);GO:0008152(metabolic process);GO:0004527(exonuclease activity);GO:0000287(magnesium ion binding);GO:0004518(nuclease activity);GO:0003729(mRNA binding);GO:0008409(5'-3' exonuclease activity);GO:0034353(RNA pyrophosphohydrolase activity);GO:0006402(mRNA catabolic process);GO:0050779(RNA destabilization);GO:0071028(nuclear mRNA surveillance);GO:0090305(nucleic acid phosphodiester bond hydrolysis)","NA","NA","NA","decapping exoribonuclease [Source:HGNC Symbol;Acc:HGNC:2992]",{"v":0.162593,"d":"0.16"},{"v":0.031124,"d":"0.03"},{"v":5.22403932656471,"d":"5.22"},{"v":2.38516575753257,"d":"2.39"},1,1,"up","no"]
[129547,0,"chr22","-",24540532,24548032,"ENST00000490922",2,567,"MSTRG.10319","GUCD1","GO:0005515(protein binding)","NA","NA","NA","guanylyl cyclase domain containing 1 [Source:HGNC Symbol;Acc:HGNC:14237]",{"v":0.166028,"d":"0.17"},0,"inf","inf",1,1,"up","no"]
[103476,0,"chr19","-",48296462,48320385,"ENST00000474199",13,2726,"MSTRG.8276","CCDC114","GO:0042995(cell projection);GO:0005515(protein binding);GO:0005929(cilium);GO:0036158(outer dynein arm assembly);GO:0003341(cilium movement);GO:0005930(axoneme);GO:0036157(outer dynein arm)","NA","NA","NA","coiled-coil domain containing 114 [Source:HGNC Symbol;Acc:HGNC:26560]",0,{"v":0.017618,"d":"0.02"},"-inf","-inf",1,1,"down","no"]
[58874,0,"chr14","-",102229073,102246247,"ENST00000520266",3,878,"MSTRG.4699","MOK","GO:0004672(protein kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0004674(protein serine/threonine kinase activity);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0042995(cell projection);GO:0051726(regulation of cell cycle);GO:0035556(intracellular signal transduction);GO:0005929(cilium);GO:0097546(ciliary base);GO:0010468(regulation of gene expression);GO:0007165(signal transduction);GO:0004693(cyclin-dependent protein serine/threonine kinase activity)","NA","NA","NA","MOK protein kinase [Source:HGNC Symbol;Acc:HGNC:9833]",{"v":0.013045,"d":"0.01"},0,"inf","inf",1,1,"up","no"]
[79912,0,"chr17","-",16440479,16440952,"ENST00000585048",2,304,"MSTRG.6465","AC093484.5","NA","NA","NA","NA","NA",{"v":0.540462,"d":"0.54"},{"v":0.258013,"d":"0.26"},{"v":2.09470840616558,"d":"2.09"},{"v":1.06674942757238,"d":"1.07"},1,1,"up","no"]
[78038,0,"chr17","-",4672858,4673535,"ENST00000573242",2,574,"ENSG00000141456","PELP1","GO:0005634(nucleus);GO:0005730(nucleolus);GO:0071391(cellular response to estrogen stimulus);GO:0003723(RNA binding);GO:0005737(cytoplasm);GO:0006351(transcription, DNA-templated);GO:0005515(protein binding);GO:0005654(nucleoplasm);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0003682(chromatin binding);GO:0008134(transcription factor binding);GO:0071339(MLL1 complex);GO:0006364(rRNA processing);GO:0035327(transcriptionally active chromatin)","NA","NA","NA","proline, glutamate and leucine rich protein 1 [Source:HGNC Symbol;Acc:HGNC:30134]",0,0,1,0,1,1,"no","no"]
[182429,0,"chr8","+",27311567,27322817,"ENST00000519650",5,559,"MSTRG.14256","PTK2B","GO:0010595(positive regulation of endothelial cell migration);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0007165(signal transduction);GO:0004871(signal transducer activity);GO:0004713(protein tyrosine kinase activity);GO:0005886(plasma membrane);GO:0005856(cytoskeleton);GO:0042995(cell projection);GO:0005515(protein binding);GO:0004715(non-membrane spanning protein tyrosine kinase activity);GO:0048471(perinuclear region of cytoplasm);GO:0030054(cell junction);GO:0007229(integrin-mediated signaling pathway);GO:0002376(immune system process);GO:0005925(focal adhesion);GO:0030500(regulation of bone mineralization);GO:0002250(adaptive immune response);GO:0045087(innate immune response);GO:0030334(regulation of cell migration);GO:0030155(regulation of cell adhesion);GO:0045453(bone resorption);GO:0045765(regulation of angiogenesis);GO:0002040(sprouting angiogenesis);GO:0005829(cytosol);GO:2000114(regulation of establishment of cell polarity);GO:0030027(lamellipodium);GO:0008285(negative regulation of cell proliferation);GO:0042127(regulation of cell proliferation);GO:0005938(cell cortex);GO:0030335(positive regulation of cell migration);GO:0007172(signal complex assembly);GO:0002688(regulation of leukocyte chemotaxis);GO:2000249(regulation of actin cytoskeleton reorganization);GO:0031234(extrinsic component of cytoplasmic side of plasma membrane);GO:0008360(regulation of cell shape);GO:0008284(positive regulation of cell proliferation);GO:0006950(response to stress);GO:0043066(negative regulation of apoptotic process);GO:0050731(positive regulation of peptidyl-tyrosine phosphorylation);GO:0070374(positive regulation of ERK1 and ERK2 cascade);GO:0006915(apoptotic process);GO:0006461(protein complex assembly);GO:0046777(protein autophosphorylation);GO:0048010(vascular endothelial growth factor receptor signaling pathway);GO:0045638(negative regulation of myeloid cell differentiation);GO:0001525(angiogenesis);GO:0002315(marginal zone B cell differentiation);GO:0001954(positive regulation of cell-matrix adhesion);GO:0030838(positive regulation of actin filament polymerization);GO:0070098(chemokine-mediated signaling pathway);GO:0033209(tumor necrosis factor-mediated signaling pathway);GO:0005102(receptor binding);GO:0007173(epidermal growth factor receptor signaling pathway);GO:0045860(positive regulation of protein kinase activity);GO:0046330(positive regulation of JNK cascade);GO:0042976(activation of Janus kinase activity);GO:2000058(regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process);GO:0007166(cell surface receptor signaling pathway);GO:0018108(peptidyl-tyrosine phosphorylation);GO:0038083(peptidyl-tyrosine autophosphorylation);GO:0043552(positive regulation of phosphatidylinositol 3-kinase activity);GO:0030502(negative regulation of bone mineralization);GO:0010976(positive regulation of neuron projection development);GO:0071300(cellular response to retinoic acid);GO:0097440(apical dendrite);GO:0043524(negative regulation of neuron apoptotic process);GO:2000310(regulation of NMDA receptor activity);GO:0043025(neuronal cell body);GO:0004972(NMDA glutamate receptor activity);GO:0004683(calmodulin-dependent protein kinase activity);GO:0019899(enzyme binding);GO:0031625(ubiquitin protein ligase binding);GO:0032403(protein complex binding);GO:0043423(3-phosphoinositide-dependent protein kinase binding);GO:0000165(MAPK cascade);GO:0000302(response to reactive oxygen species);GO:0001556(oocyte maturation);GO:0001666(response to hypoxia);GO:0006968(cellular defense response);GO:0006970(response to osmotic stress);GO:0007015(actin filament organization);GO:0007155(cell adhesion);GO:0007204(positive regulation of cytosolic calcium ion concentration);GO:0009612(response to mechanical stimulus);GO:0009725(response to hormone);GO:0009749(response to glucose);GO:0010226(response to lithium ion);GO:0010243(response to organonitrogen compound);GO:0010656(negative regulation of muscle cell apoptotic process);GO:0010752(regulation of cGMP-mediated signaling);GO:0010758(regulation of macrophage chemotaxis);GO:0014009(glial cell proliferation);GO:0030154(cell differentiation);GO:0030279(negative regulation of ossification);GO:0030307(positive regulation of cell growth);GO:0030826(regulation of cGMP biosynthetic process);GO:0031175(neuron projection development);GO:0032270(positive regulation of cellular protein metabolic process);GO:0032960(regulation of inositol trisphosphate biosynthetic process);GO:0035235(ionotropic glutamate receptor signaling pathway);GO:0035902(response to immobilization stress);GO:0042220(response to cocaine);GO:0042493(response to drug);GO:0042542(response to hydrogen peroxide);GO:0043149(stress fiber assembly);GO:0043267(negative regulation of potassium ion transport);GO:0043507(positive regulation of JUN kinase activity);GO:0043534(blood vessel endothelial cell migration);GO:0045428(regulation of nitric oxide biosynthetic process);GO:0045429(positive regulation of nitric oxide biosynthetic process);GO:0045471(response to ethanol);GO:0045727(positive regulation of translation);GO:0045766(positive regulation of angiogenesis);GO:0048041(focal adhesion assembly);GO:0050848(regulation of calcium-mediated signaling);GO:0051000(positive regulation of nitric-oxide synthase activity);GO:0051279(regulation of release of sequestered calcium ion into cytosol);GO:0051591(response to cAMP);GO:0051592(response to calcium ion);GO:0051968(positive regulation of synaptic transmission, glutamatergic);GO:0060291(long-term synaptic potentiation);GO:0060292(long term synaptic depression);GO:0071498(cellular response to fluid shear stress);GO:0090630(activation of GTPase activity);GO:2000060(positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process);GO:2000379(positive regulation of reactive oxygen species metabolic process);GO:2000463(positive regulation of excitatory postsynaptic potential);GO:2000538(positive regulation of B cell chemotaxis);GO:2000573(positive regulation of DNA biosynthetic process);GO:0014069(postsynaptic density);GO:0017146(NMDA selective glutamate receptor complex);GO:0030424(axon);GO:0030425(dendrite);GO:0030426(growth cone);GO:0043197(dendritic spine);GO:0044297(cell body);GO:0045121(membrane raft)","04020(Calcium signaling pathway);04072(Phospholipase D signaling pathway);04650(Natural killer cell mediated cytotoxicity);04670(Leukocyte transendothelial migration);04062(Chemokine signaling pathway);04912(GnRH signaling pathway);05161(Hepatitis B)","NA","NA","protein tyrosine kinase 2 beta [Source:HGNC Symbol;Acc:HGNC:9612]",{"v":0.094696,"d":"0.09"},0,"inf","inf",1,1,"up","no"]
[26107,0,"chr11","-",6599943,6603604,"ENST00000533907",5,1989,"MSTRG.2210","RRP8","GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005730(nucleolus);GO:0005829(cytosol);GO:0008168(methyltransferase activity);GO:0016740(transferase activity);GO:0032259(methylation);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0016569(covalent chromatin modification);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0006364(rRNA processing);GO:0005654(nucleoplasm);GO:0035064(methylated histone binding);GO:0008757(S-adenosylmethionine-dependent methyltransferase activity);GO:0000183(chromatin silencing at rDNA);GO:0042149(cellular response to glucose starvation);GO:0046015(regulation of transcription by glucose);GO:0071158(positive regulation of cell cycle arrest);GO:0072332(intrinsic apoptotic signaling pathway by p53 class mediator);GO:0005677(chromatin silencing complex);GO:0033553(rDNA heterochromatin)","NA","NA","NA","ribosomal RNA processing 8 [Source:HGNC Symbol;Acc:HGNC:29030]",{"v":0.019544,"d":"0.02"},{"v":0.0118,"d":"0.01"},{"v":1.65627118644068,"d":"1.66"},{"v":0.72793890913069,"d":"0.73"},1,1,"up","no"]
[154642,0,"chr5","+",43651784,43653580,"ENST00000513390",2,664,"MSTRG.12034","NNT","GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0006099(tricarboxylic acid cycle);GO:0005743(mitochondrial inner membrane);GO:0005739(mitochondrion);GO:0008746(NAD(P)+ transhydrogenase activity);GO:0015992(proton transport);GO:0051287(NAD binding);GO:1902600(hydrogen ion transmembrane transport);GO:0072593(reactive oxygen species metabolic process);GO:0050661(NADP binding);GO:0003957(NAD(P)+ transhydrogenase (B-specific) activity);GO:0008750(NAD(P)+ transhydrogenase (AB-specific) activity);GO:0006740(NADPH regeneration);GO:0005746(mitochondrial respiratory chain)","00760(Nicotinate and nicotinamide metabolism)","NA","NA","nicotinamide nucleotide transhydrogenase [Source:HGNC Symbol;Acc:HGNC:7863]",0,0,1,0,1,1,"no","no"]
[56147,0,"chr14","-",67678087,67692483,"ENST00000554035",5,849,"MSTRG.4491","RDH11","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005622(intracellular);GO:0001523(retinoid metabolic process);GO:0004745(retinol dehydrogenase activity);GO:0052650(NADP-retinol dehydrogenase activity);GO:0042572(retinol metabolic process);GO:0016616(oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor);GO:0042574(retinal metabolic process)","00830(Retinol metabolism)","NA","NA","retinol dehydrogenase 11 (all-trans/9-cis/11-cis) [Source:HGNC Symbol;Acc:HGNC:17964]",{"v":0.110754,"d":"0.11"},{"v":0.154804,"d":"0.15"},{"v":0.715446629286065,"d":"0.72"},{"v":-0.483083945735808,"d":"-0.48"},1,1,"down","no"]
[36019,0,"chr11","+",119121609,119131600,"ENST00000531360",3,748,"ENSG00000172273","HINFP","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0005829(cytosol);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0030054(cell junction);GO:0006281(DNA repair);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:0001078(transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0003682(chromatin binding);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0001701(in utero embryonic development);GO:0010628(positive regulation of gene expression);GO:0045893(positive regulation of transcription, DNA-templated);GO:0003713(transcription coactivator activity);GO:0005654(nucleoplasm);GO:0005515(protein binding);GO:0019899(enzyme binding);GO:0010629(negative regulation of gene expression);GO:0042393(histone binding);GO:0044212(transcription regulatory region DNA binding);GO:0045892(negative regulation of transcription, DNA-templated);GO:0000077(DNA damage checkpoint);GO:0000083(regulation of transcription involved in G1/S transition of mitotic cell cycle);GO:0015030(Cajal body);GO:0045184(establishment of protein localization);GO:0010468(regulation of gene expression);GO:0045445(myoblast differentiation);GO:0000082(G1/S transition of mitotic cell cycle)","NA","NA","NA","histone H4 transcription factor [Source:HGNC Symbol;Acc:HGNC:17850]",0,0,1,0,1,1,"no","no"]
[27840,0,"chr11","-",32602246,32794641,"ENST00000335185",18,3849,"MSTRG.2311","CCDC73","NA","NA","NA","NA","coiled-coil domain containing 73 [Source:HGNC Symbol;Acc:HGNC:23261]",{"v":0.060856,"d":"0.06"},{"v":0.035259,"d":"0.04"},{"v":1.72597067415412,"d":"1.73"},{"v":0.787407951995517,"d":"0.79"},1,1,"up","no"]
[44162,0,"chr12","+",68610929,68656398,"ENST00000540781",6,571,"MSTRG.3540","RAP1B","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005525(GTP binding);GO:0000166(nucleotide binding);GO:0007165(signal transduction);GO:0003924(GTPase activity);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0030054(cell junction);GO:0007264(small GTPase mediated signal transduction);GO:0008283(cell proliferation);GO:0009743(response to carbohydrate);GO:0035690(cellular response to drug);GO:0045955(negative regulation of calcium ion-dependent exocytosis);GO:0070374(positive regulation of ERK1 and ERK2 cascade);GO:0071407(cellular response to organic cyclic compound);GO:0097211(cellular response to gonadotropin-releasing hormone);GO:2000301(negative regulation of synaptic vesicle exocytosis);GO:2000114(regulation of establishment of cell polarity);GO:0070062(extracellular exosome);GO:0043312(neutrophil degranulation);GO:0035722(interleukin-12-mediated signaling pathway);GO:0019003(GDP binding);GO:0032403(protein complex binding);GO:0061028(establishment of endothelial barrier);GO:0035577(azurophil granule membrane);GO:0005911(cell-cell junction);GO:0005811(lipid particle);GO:0005622(intracellular);GO:0071320(cellular response to cAMP);GO:0032486(Rap protein signal transduction);GO:1901888(regulation of cell junction assembly)","04014(Ras signaling pathway);04015(Rap1 signaling pathway);04010(MAPK signaling pathway);04024(cAMP signaling pathway);04510(Focal adhesion);04611(Platelet activation);04670(Leukocyte transendothelial migration);04062(Chemokine signaling pathway);04972(Pancreatic secretion);04720(Long-term potentiation);04722(Neurotrophin signaling pathway);05211(Renal cell carcinoma)","NA","NA","RAP1B, member of RAS oncogene family [Source:HGNC Symbol;Acc:HGNC:9857]",{"v":0.405447,"d":"0.41"},{"v":0.660075,"d":"0.66"},{"v":0.614243835927736,"d":"0.61"},{"v":-0.703116619989964,"d":"-0.70"},1,1,"down","no"]
[134908,0,"chr3","-",39100457,39107614,"ENST00000488479",3,539,"MSTRG.10831","GORASP1","GO:0006810(transport);GO:0016020(membrane);GO:0015031(protein transport);GO:0005794(Golgi apparatus);GO:0005515(protein binding);GO:0006487(protein N-linked glycosylation);GO:0007030(Golgi organization);GO:0006888(ER to Golgi vesicle-mediated transport);GO:0000139(Golgi membrane);GO:0048208(COPII vesicle coating);GO:0033116(endoplasmic reticulum-Golgi intermediate compartment membrane);GO:1904668(positive regulation of ubiquitin protein ligase activity);GO:0050774(negative regulation of dendrite morphogenesis)","NA","NA","NA","golgi reassembly stacking protein 1 [Source:HGNC Symbol;Acc:HGNC:16769]",{"v":0.038864,"d":"0.04"},{"v":0.00742,"d":"0.01"},{"v":5.2377358490566,"d":"5.24"},{"v":2.3889433031277,"d":"2.39"},1,1,"up","no"]
[96374,"j","chr19","-",10315471,10333711,"MSTRG.7797.13",18,3599,"MSTRG.7797","RAVER1","NA","NA","NA","NA","NA",{"v":1.840228,"d":"1.84"},{"v":0.041426,"d":"0.04"},{"v":44.4220537826486,"d":"44.42"},{"v":5.47320419001329,"d":"5.47"},1,1,"up","no"]
[191343,0,"chr9","-",83661911,83665393,"ENST00000527373",3,562,"MSTRG.14814","UBQLN1","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0005783(endoplasmic reticulum);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0000502(proteasome complex);GO:0048471(perinuclear region of cytoplasm);GO:0006914(autophagy);GO:0031410(cytoplasmic vesicle);GO:0042802(identical protein binding);GO:0000045(autophagosome assembly);GO:0005776(autophagosome);GO:0031398(positive regulation of protein ubiquitination);GO:0030433(ubiquitin-dependent ERAD pathway);GO:0016236(macroautophagy);GO:0071456(cellular response to hypoxia);GO:0034976(response to endoplasmic reticulum stress);GO:0016235(aggresome);GO:0019900(kinase binding);GO:1902175(regulation of oxidative stress-induced intrinsic apoptotic signaling pathway);GO:0043234(protein complex);GO:0031593(polyubiquitin binding);GO:1903071(positive regulation of ER-associated ubiquitin-dependent protein catabolic process);GO:0097352(autophagosome maturation);GO:0035973(aggrephagy);GO:0031396(regulation of protein ubiquitination);GO:0034140(negative regulation of toll-like receptor 3 signaling pathway);GO:1901340(negative regulation of store-operated calcium channel activity)","04141(Protein processing in endoplasmic reticulum)","NA","NA","ubiquilin 1 [Source:HGNC Symbol;Acc:HGNC:12508]",{"v":0.106832,"d":"0.11"},{"v":0.37255,"d":"0.37"},{"v":0.286758824318883,"d":"0.29"},{"v":-1.80209021246419,"d":"-1.80"},1,1,"down","no"]
[65089,0,"chr15","+",76337438,76338514,"ENST00000558437",2,793,"ENSG00000159556","ISL2","GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0043565(sequence-specific DNA binding);GO:0007275(multicellular organism development);GO:0048666(neuron development);GO:0048935(peripheral nervous system neuron development);GO:0021520(spinal cord motor neuron cell fate specification);GO:0021524(visceral motor neuron differentiation);GO:0031290(retinal ganglion cell axon guidance);GO:0045665(negative regulation of neuron differentiation);GO:0048663(neuron fate commitment)","NA","NA","NA","ISL LIM homeobox 2 [Source:HGNC Symbol;Acc:HGNC:18524]",0,0,1,0,1,1,"no","no"]
[161609,0,"chr5","-",177491072,177492572,"ENST00000504318",4,597,"MSTRG.12580","PDLIM7","GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0005634(nucleus);GO:0005925(focal adhesion);GO:0015629(actin cytoskeleton);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0007275(multicellular organism development);GO:0030154(cell differentiation);GO:0005829(cytosol);GO:0001503(ossification);GO:0005913(cell-cell adherens junction);GO:0007411(axon guidance);GO:0006898(receptor-mediated endocytosis);GO:0030036(actin cytoskeleton organization);GO:0045669(positive regulation of osteoblast differentiation);GO:0001725(stress fiber);GO:0001726(ruffle)","NA","NA","NA","PDZ and LIM domain 7 [Source:HGNC Symbol;Acc:HGNC:22958]",{"v":0.149961,"d":"0.15"},{"v":0.163083,"d":"0.16"},{"v":0.919537904012067,"d":"0.92"},{"v":-0.121019050099884,"d":"-0.12"},1,1,"down","no"]
[144565,0,"chr3","-",195971253,195975902,"ENST00000457601",3,560,"ENSG00000185485","SDHAP1","NA","NA","NA","NA","succinate dehydrogenase complex flavoprotein subunit A pseudogene 1 [Source:HGNC Symbol;Acc:HGNC:32455]",{"v":0.405682,"d":"0.41"},{"v":0.037764,"d":"0.04"},{"v":10.742559050948,"d":"10.74"},{"v":3.4252658023949,"d":"3.43"},1,1,"up","no"]
[104682,0,"chr19","+",51415906,51417425,"ENST00000532688",3,729,"MSTRG.8377","AC008750.2","NA","NA","NA","NA","NA",{"v":0.160462,"d":"0.16"},{"v":0.250191,"d":"0.25"},{"v":0.641358002486101,"d":"0.64"},{"v":-0.640798208817123,"d":"-0.64"},1,1,"down","no"]
[98902,0,"chr19","+",19344252,19357755,"ENST00000262816",9,3838,"MSTRG.8017","MAU2","GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0051301(cell division);GO:0007049(cell cycle);GO:0016604(nuclear body);GO:0003690(double-stranded DNA binding);GO:0007059(chromosome segregation);GO:0005515(protein binding);GO:0007064(mitotic sister chromatid cohesion);GO:0047485(protein N-terminus binding);GO:0000785(chromatin);GO:0034088(maintenance of mitotic sister chromatid cohesion);GO:0032116(SMC loading complex)","NA","NA","NA","MAU2 sister chromatid cohesion factor [Source:HGNC Symbol;Acc:HGNC:29140]",{"v":0.155912,"d":"0.16"},{"v":0.067605,"d":"0.07"},{"v":2.3062199541454,"d":"2.31"},{"v":1.20553011560109,"d":"1.21"},1,1,"up","no"]
[97590,0,"chr19","-",14477764,14480596,"ENST00000585606",3,2071,"MSTRG.7903","GIPC1","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005829(cytosol);GO:0005515(protein binding);GO:0007186(G-protein coupled receptor signaling pathway);GO:0031410(cytoplasmic vesicle);GO:0003779(actin binding);GO:0017022(myosin binding);GO:0030165(PDZ domain binding);GO:0042803(protein homodimerization activity);GO:0006605(protein targeting);GO:0007268(chemical synaptic transmission);GO:0014047(glutamate secretion);GO:0030511(positive regulation of transforming growth factor beta receptor signaling pathway);GO:0031647(regulation of protein stability);GO:0032435(negative regulation of proteasomal ubiquitin-dependent protein catabolic process);GO:0043542(endothelial cell migration);GO:0048167(regulation of synaptic plasticity);GO:0005903(brush border);GO:0008021(synaptic vesicle);GO:0012506(vesicle membrane);GO:0030139(endocytic vesicle);GO:0043197(dendritic spine);GO:0043198(dendritic shaft);GO:0045296(cadherin binding);GO:0070062(extracellular exosome);GO:0005938(cell cortex);GO:0005102(receptor binding);GO:0032467(positive regulation of cytokinesis)","NA","NA","NA","GIPC PDZ domain containing family member 1 [Source:HGNC Symbol;Acc:HGNC:1226]",{"v":0.069763,"d":"0.07"},{"v":0.00021,"d":"0.00"},{"v":332.204761904762,"d":"332.20"},{"v":8.37592894316877,"d":"8.38"},1,1,"up","no"]
[158911,0,"chr5","-",139108007,139196528,"ENST00000504666",4,547,"MSTRG.12379","SIL1","GO:0006810(transport);GO:0015031(protein transport);GO:0005783(endoplasmic reticulum);GO:0005515(protein binding);GO:0005615(extracellular space);GO:0006886(intracellular protein transport);GO:0005788(endoplasmic reticulum lumen);GO:0006457(protein folding);GO:0051082(unfolded protein binding)","04141(Protein processing in endoplasmic reticulum)","NA","NA","SIL1 nucleotide exchange factor [Source:HGNC Symbol;Acc:HGNC:24624]",{"v":1.12E-4,"d":"0.00"},0,"inf","inf",1,1,"up","no"]
[102275,0,"chr19","-",43501530,43504644,"ENST00000596902",4,808,"ENSG00000176531","PHLDB3","GO:0019899(enzyme binding)","NA","NA","NA","pleckstrin homology like domain family B member 3 [Source:HGNC Symbol;Acc:HGNC:30499]",{"v":0.302202,"d":"0.30"},0,"inf","inf",1,1,"up","no"]
[174886,0,"chr7","-",73570886,73578619,"ENST00000426966",8,1196,"ENSG00000106638","TBL2","GO:0003723(RNA binding);GO:0005783(endoplasmic reticulum);GO:0019901(protein kinase binding);GO:0042149(cellular response to glucose starvation);GO:0030176(integral component of endoplasmic reticulum membrane);GO:0071456(cellular response to hypoxia);GO:0031369(translation initiation factor binding);GO:0030968(endoplasmic reticulum unfolded protein response);GO:0051219(phosphoprotein binding)","NA","NA","NA","transducin beta like 2 [Source:HGNC Symbol;Acc:HGNC:11586]",{"v":0.503701,"d":"0.50"},{"v":1.005543,"d":"1.01"},{"v":0.500924376182819,"d":"0.50"},{"v":-0.997335276578852,"d":"-1.00"},1,1,"down","no"]
[196091,0,"chrX","+",21855987,21858727,"ENST00000429584",1,2741,"ENSG00000230797","YY2","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006366(transcription from RNA polymerase II promoter);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0001228(transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding);GO:0043565(sequence-specific DNA binding);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0000987(core promoter proximal region sequence-specific DNA binding)","NA","NA","NA","YY2 transcription factor [Source:HGNC Symbol;Acc:HGNC:31684]",0,{"v":0.046479,"d":"0.05"},"-inf","-inf",1,1,"down","no"]
[51893,0,"chr13","+",112873432,112876094,"ENST00000495930",2,564,"ENSG00000068650","ATP11A","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0043231(intracellular membrane-bounded organelle);GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0000287(magnesium ion binding);GO:0016787(hydrolase activity);GO:0005765(lysosomal membrane);GO:0005783(endoplasmic reticulum);GO:0005886(plasma membrane);GO:0006869(lipid transport);GO:0004012(phospholipid-translocating ATPase activity);GO:0015914(phospholipid transport);GO:0005515(protein binding);GO:0005768(endosome);GO:0005769(early endosome);GO:0055037(recycling endosome);GO:0043312(neutrophil degranulation);GO:0035579(specific granule membrane);GO:0070821(tertiary granule membrane);GO:0045332(phospholipid translocation)","NA","NA","NA","ATPase phospholipid transporting 11A [Source:HGNC Symbol;Acc:HGNC:13552]",{"v":0.611506,"d":"0.61"},{"v":0.057625,"d":"0.06"},{"v":10.6118177874187,"d":"10.61"},{"v":3.40759990366269,"d":"3.41"},1,1,"up","no"]
[123305,0,"chr20","-",35630983,35664916,"ENST00000414664",11,1070,"MSTRG.9710","CPNE1","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005654(nucleoplasm);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0031965(nuclear membrane);GO:0005829(cytosol);GO:0042803(protein homodimerization activity);GO:0005886(plasma membrane);GO:0006508(proteolysis);GO:0030154(cell differentiation);GO:0005509(calcium ion binding);GO:0005515(protein binding);GO:0070062(extracellular exosome);GO:0043312(neutrophil degranulation);GO:0010629(negative regulation of gene expression);GO:0005215(transporter activity);GO:0016192(vesicle-mediated transport);GO:0035577(azurophil granule membrane);GO:0006629(lipid metabolic process);GO:0004175(endopeptidase activity);GO:0051897(positive regulation of protein kinase B signaling);GO:0051059(NF-kappaB binding);GO:0043122(regulation of I-kappaB kinase/NF-kappaB signaling);GO:0071277(cellular response to calcium ion);GO:1901223(negative regulation of NIK/NF-kappaB signaling);GO:0005544(calcium-dependent phospholipid binding);GO:0046474(glycerophospholipid biosynthetic process);GO:0043392(negative regulation of DNA binding);GO:1903265(positive regulation of tumor necrosis factor-mediated signaling pathway);GO:0045666(positive regulation of neuron differentiation);GO:1990138(neuron projection extension);GO:0001786(phosphatidylserine binding)","NA","NA","NA","copine 1 [Source:HGNC Symbol;Acc:HGNC:2314]",{"v":0.051075,"d":"0.05"},{"v":3.393516,"d":"3.39"},{"v":0.0150507615110699,"d":"0.02"},{"v":-6.05401970608207,"d":"-6.05"},1,1,"down","no"]
[189432,0,"chr9","+",21994791,22121095,"ENST00000428597",19,3835,"ENSG00000240498","CDKN2B-AS1","NA","NA","NA","NA","CDKN2B antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:34341]",{"v":0.02255,"d":"0.02"},{"v":0.039284,"d":"0.04"},{"v":0.574025048365747,"d":"0.57"},{"v":-0.800814402647398,"d":"-0.80"},1,1,"down","no"]
[92752,0,"chr18","-",56040332,56068370,"ENST00000589754",3,555,"ENSG00000206129","AC006305.1","NA","NA","NA","NA","NA",{"v":0.068582,"d":"0.07"},0,"inf","inf",1,1,"up","no"]
[83554,0,"chr17","+",42480263,42487353,"ENST00000587882",3,780,"MSTRG.6830","ATP6V0A1","GO:0006810(transport);GO:0016607(nuclear speck);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005794(Golgi apparatus);GO:0043231(intracellular membrane-bounded organelle);GO:0005829(cytosol);GO:0006811(ion transport);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0042470(melanosome);GO:0030659(cytoplasmic vesicle membrane);GO:0031410(cytoplasmic vesicle);GO:0015078(hydrogen ion transmembrane transporter activity);GO:0015991(ATP hydrolysis coupled proton transport);GO:0015992(proton transport);GO:0000220(vacuolar proton-transporting V-type ATPase, V0 domain);GO:0033179(proton-transporting V-type ATPase, V0 domain);GO:0070062(extracellular exosome);GO:0034220(ion transmembrane transport);GO:0010008(endosome membrane);GO:0043312(neutrophil degranulation);GO:0030670(phagocytic vesicle membrane);GO:0030667(secretory granule membrane);GO:0008286(insulin receptor signaling pathway);GO:0016241(regulation of macroautophagy);GO:0033572(transferrin transport);GO:0090383(phagosome acidification);GO:0101003(ficolin-1-rich granule membrane);GO:0051117(ATPase binding);GO:0015986(ATP synthesis coupled proton transport);GO:0005765(lysosomal membrane);GO:0046961(proton-transporting ATPase activity, rotational mechanism);GO:0070072(vacuolar proton-transporting V-type ATPase complex assembly);GO:0016471(vacuolar proton-transporting V-type ATPase complex);GO:0007035(vacuolar acidification);GO:1901998(toxin transport);GO:0005737(cytoplasm)","00190(Oxidative phosphorylation);04145(Phagosome);04142(Lysosome);04966(Collecting duct acid secretion);04721(Synaptic vesicle cycle);05323(Rheumatoid arthritis);05110(Vibrio cholerae infection);05120(Epithelial cell signaling in Helicobacter pylori infection);05152(Tuberculosis);05165(Human papillomavirus infection)","NA","NA","ATPase H+ transporting V0 subunit a1 [Source:HGNC Symbol;Acc:HGNC:865]",0,{"v":0.079701,"d":"0.08"},"-inf","-inf",1,1,"down","no"]
[143850,0,"chr3","+",186783305,186785047,"ENST00000445596",4,600,"MSTRG.11403","EIF4A2","GO:0003676(nucleic acid binding);GO:0005524(ATP binding);GO:0003723(RNA binding);GO:0003743(translation initiation factor activity);GO:0006412(translation);GO:0006413(translational initiation);GO:0000166(nucleotide binding);GO:0016787(hydrolase activity);GO:0004386(helicase activity);GO:0005515(protein binding);GO:0048471(perinuclear region of cytoplasm);GO:0005730(nucleolus);GO:0005829(cytosol);GO:0004004(ATP-dependent RNA helicase activity);GO:0010501(RNA secondary structure unwinding);GO:0000289(nuclear-transcribed mRNA poly(A) tail shortening);GO:0016032(viral process);GO:0016887(ATPase activity);GO:0006446(regulation of translational initiation);GO:0016281(eukaryotic translation initiation factor 4F complex);GO:1900260(negative regulation of RNA-directed 5'-3' RNA polymerase activity);GO:1990830(cellular response to leukemia inhibitory factor)","03013(RNA transport)","NA","NA","eukaryotic translation initiation factor 4A2 [Source:HGNC Symbol;Acc:HGNC:3284]",0,{"v":0.044334,"d":"0.04"},"-inf","-inf",1,1,"down","no"]
[137335,0,"chr3","+",54987678,55074216,"ENST00000478261",7,760,"ENSG00000157445","CACNA2D3","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0046872(metal ion binding);GO:0005244(voltage-gated ion channel activity);GO:0006811(ion transport);GO:0034765(regulation of ion transmembrane transport);GO:0006816(calcium ion transport);GO:0005262(calcium channel activity);GO:0070588(calcium ion transmembrane transport);GO:0005886(plasma membrane);GO:0061337(cardiac conduction)","04010(MAPK signaling pathway);04921(Oxytocin signaling pathway);04260(Cardiac muscle contraction);04261(Adrenergic signaling in cardiomyocytes);05410(Hypertrophic cardiomyopathy (HCM));05412(Arrhythmogenic right ventricular cardiomyopathy (ARVC));05414(Dilated cardiomyopathy (DCM))","NA","NA","calcium voltage-gated channel auxiliary subunit alpha2delta 3 [Source:HGNC Symbol;Acc:HGNC:15460]",0,{"v":0.124956,"d":"0.12"},"-inf","-inf",1,1,"down","no"]
[152669,0,"chr4","+",185018841,185020802,"ENST00000513599",3,1099,"ENSG00000187821","HELT","GO:0005634(nucleus);GO:0046983(protein dimerization activity);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:0001078(transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0042803(protein homodimerization activity);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0001967(suckling behavior);GO:0007417(central nervous system development);GO:0009791(post-embryonic development);GO:0010259(multicellular organism aging);GO:0010467(gene expression);GO:0021858(GABAergic neuron differentiation in basal ganglia);GO:0030182(neuron differentiation);GO:0035264(multicellular organism growth);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0005667(transcription factor complex)","NA","NA","NA","helt bHLH transcription factor [Source:HGNC Symbol;Acc:HGNC:33783]",0,0,1,0,1,1,"no","no"]
[167043,0,"chr6","-",67887646,67889339,"ENST00000412872",2,1605,"ENSG00000227706","AL713998.1","NA","NA","NA","NA","NA",0,0,1,0,1,1,"no","no"]
[54988,0,"chr14","+",51847126,51979342,"ENST00000553560",4,479,"MSTRG.4391","GNG2","GO:0016020(membrane);GO:0007186(G-protein coupled receptor signaling pathway);GO:0004871(signal transducer activity);GO:0005886(plasma membrane);GO:0007165(signal transduction);GO:0005834(heterotrimeric G-protein complex);GO:0070062(extracellular exosome);GO:0006457(protein folding);GO:0030168(platelet activation);GO:0071377(cellular response to glucagon stimulus);GO:0071380(cellular response to prostaglandin E stimulus);GO:0071870(cellular response to catecholamine stimulus);GO:0007223(Wnt signaling pathway, calcium modulating pathway);GO:0031681(G-protein beta-subunit binding);GO:0007191(adenylate cyclase-activating dopamine receptor signaling pathway);GO:0008283(cell proliferation)","04014(Ras signaling pathway);04371(Apelin signaling pathway);04151(PI3K-Akt signaling pathway);04062(Chemokine signaling pathway);04926(Relaxin signaling pathway);04724(Glutamatergic synapse);04727(GABAergic synapse);04725(Cholinergic synapse);04728(Dopaminergic synapse);04726(Serotonergic synapse);04723(Retrograde endocannabinoid signaling);04713(Circadian entrainment);05200(Pathways in cancer);05032(Morphine addiction);05034(Alcoholism);05167(Kaposi's sarcoma-associated herpesvirus infection)","NA","NA","G protein subunit gamma 2 [Source:HGNC Symbol;Acc:HGNC:4404]",{"v":0.067736,"d":"0.07"},0,"inf","inf",1,1,"up","no"]
[11655,0,"chr1","-",155200899,155203305,"ENST00000460050",8,879,"MSTRG.1034","THBS3","GO:0005509(calcium ion binding);GO:0007155(cell adhesion);GO:0005576(extracellular region);GO:0048471(perinuclear region of cytoplasm);GO:0008201(heparin binding);GO:0007160(cell-matrix adhesion);GO:0003417(growth plate cartilage development);GO:0043931(ossification involved in bone maturation);GO:0060346(bone trabecula formation)","04151(PI3K-Akt signaling pathway);04512(ECM-receptor interaction);04145(Phagosome);04510(Focal adhesion);05165(Human papillomavirus infection);05144(Malaria)","NA","NA","thrombospondin 3 [Source:HGNC Symbol;Acc:HGNC:11787]",{"v":0.08007,"d":"0.08"},0,"inf","inf",1,1,"up","no"]
[56927,0,"chr14","+",75069280,75079987,"ENST00000524913",3,4283,"MSTRG.4550","ZC2HC1C","GO:0046872(metal ion binding);GO:0005515(protein binding)","NA","NA","NA","zinc finger C2HC-type containing 1C [Source:HGNC Symbol;Acc:HGNC:20354]",{"v":0.029815,"d":"0.03"},0,"inf","inf",1,1,"up","no"]
[71410,0,"chr16","+",28951007,28952562,"ENST00000565752",2,823,"MSTRG.5781","NFATC2IP","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016925(protein sumoylation);GO:0031386(protein tag);GO:0001816(cytokine production);GO:0045944(positive regulation of transcription from RNA polymerase II promoter)","NA","NA","NA","nuclear factor of activated T-cells 2 interacting protein [Source:HGNC Symbol;Acc:HGNC:25906]",{"v":0.19367,"d":"0.19"},{"v":0.059329,"d":"0.06"},{"v":3.26433953041514,"d":"3.26"},{"v":1.70679112268034,"d":"1.71"},1,1,"up","no"]
[90230,0,"chr18","+",2578123,2579196,"ENST00000574567",2,289,"ENSG00000080986","NDC80","GO:0005634(nucleus);GO:0016020(membrane);GO:0005654(nucleoplasm);GO:0051301(cell division);GO:0005694(chromosome);GO:0005813(centrosome);GO:0005515(protein binding);GO:0007049(cell cycle);GO:0042802(identical protein binding);GO:0007059(chromosome segregation);GO:0000775(chromosome, centromeric region);GO:0000776(kinetochore);GO:0000777(condensed chromosome kinetochore);GO:0005829(cytosol);GO:0005200(structural constituent of cytoskeleton);GO:0007052(mitotic spindle organization);GO:0007062(sister chromatid cohesion);GO:0000070(mitotic sister chromatid segregation);GO:0000132(establishment of mitotic spindle orientation);GO:0000278(mitotic cell cycle);GO:0008608(attachment of spindle microtubules to kinetochore);GO:0051310(metaphase plate congression);GO:0051315(attachment of mitotic spindle microtubules to kinetochore);GO:0051383(kinetochore organization);GO:0090267(positive regulation of mitotic cell cycle spindle assembly checkpoint);GO:1905342(positive regulation of protein localization to kinetochore);GO:0000942(condensed nuclear chromosome outer kinetochore);GO:0031262(Ndc80 complex)","NA","NA","NA","NDC80, kinetochore complex component [Source:HGNC Symbol;Acc:HGNC:16909]",{"v":0.172913,"d":"0.17"},0,"inf","inf",1,1,"up","no"]
[2222,0,"chr1","+",19210501,19240704,"ENST00000437898",2,507,"MSTRG.207","AL035413.1","NA","NA","NA","NA","NA",{"v":0.517081,"d":"0.52"},{"v":0.044919,"d":"0.04"},{"v":11.5114094258554,"d":"11.51"},{"v":3.52499257885332,"d":"3.52"},1,1,"up","no"]
[67542,0,"chr16","+",668105,671162,"ENST00000563776",9,923,"MSTRG.5485","RHOT2","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005525(GTP binding);GO:0007264(small GTPase mediated signal transduction);GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0016787(hydrolase activity);GO:0005509(calcium ion binding);GO:0003924(GTPase activity);GO:0005739(mitochondrion);GO:0005515(protein binding);GO:0005741(mitochondrial outer membrane);GO:0007005(mitochondrion organization);GO:0005886(plasma membrane);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0051056(regulation of small GTPase mediated signal transduction);GO:0047497(mitochondrion transport along microtubule);GO:0031307(integral component of mitochondrial outer membrane);GO:0019725(cellular homeostasis);GO:0097345(mitochondrial outer membrane permeabilization)","04137(Mitophagy - animal)","NA","NA","ras homolog family member T2 [Source:HGNC Symbol;Acc:HGNC:21169]",0,{"v":0.066598,"d":"0.07"},"-inf","-inf",1,1,"down","no"]
[183872,0,"chr8","-",53993704,54021929,"ENST00000521836",4,625,"MSTRG.14356","TCEA1","GO:0005634(nucleus);GO:0003676(nucleic acid binding);GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0005730(nucleolus);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0005654(nucleoplasm);GO:0006366(transcription from RNA polymerase II promoter);GO:0006368(transcription elongation from RNA polymerase II promoter);GO:0006283(transcription-coupled nucleotide-excision repair);GO:0005669(transcription factor TFIID complex);GO:0003746(translation elongation factor activity);GO:0006414(translational elongation)","NA","NA","NA","transcription elongation factor A1 [Source:HGNC Symbol;Acc:HGNC:11612]",{"v":0.254229,"d":"0.25"},{"v":0.045281,"d":"0.05"},{"v":5.6144740619686,"d":"5.61"},{"v":2.48915088393887,"d":"2.49"},1,1,"up","no"]
[85938,0,"chr17","-",57078298,57085022,"ENST00000576871",3,713,"ENSG00000263004","AC007114.1","NA","NA","NA","NA","NA",0,0,1,0,1,1,"no","no"]
[89779,0,"chr17","+",82229062,82236895,"ENST00000578574",2,958,"MSTRG.7355","SLC16A3","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0055085(transmembrane transport);GO:0005887(integral component of plasma membrane);GO:0008028(monocarboxylic acid transmembrane transporter activity);GO:0015129(lactate transmembrane transporter activity);GO:0015718(monocarboxylic acid transport);GO:0035873(lactate transmembrane transport);GO:0003723(RNA binding);GO:0006810(transport);GO:0031965(nuclear membrane);GO:0005886(plasma membrane);GO:0015293(symporter activity);GO:0005515(protein binding);GO:0050900(leukocyte migration);GO:0006090(pyruvate metabolic process);GO:0035879(plasma membrane lactate transport)","05230(Central carbon metabolism in cancer)","NA","NA","solute carrier family 16 member 3 [Source:HGNC Symbol;Acc:HGNC:10924]",{"v":0.666181,"d":"0.67"},{"v":0.102537,"d":"0.10"},{"v":6.49698157738182,"d":"6.50"},{"v":2.69976961433354,"d":"2.70"},1,1,"up","no"]
[14680,0,"chr1","-",200666259,200669708,"ENST00000436897",2,635,"MSTRG.1279","DDX59","GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0016787(hydrolase activity);GO:0004386(helicase activity);GO:0005730(nucleolus);GO:0004004(ATP-dependent RNA helicase activity);GO:0010501(RNA secondary structure unwinding);GO:0005622(intracellular);GO:0016020(membrane);GO:0016021(integral component of membrane)","NA","NA","NA","DEAD-box helicase 59 [Source:HGNC Symbol;Acc:HGNC:25360]",{"v":0.045257,"d":"0.05"},{"v":0.044179,"d":"0.04"},{"v":1.02440073338011,"d":"1.02"},{"v":0.034780190890144,"d":"0.03"},1,1,"up","no"]
[126384,0,"chr21","-",28966895,28986761,"ENST00000483326",10,1753,"ENSG00000198862","LTN1","GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0016740(transferase activity);GO:0016567(protein ubiquitination);GO:0005515(protein binding);GO:0004842(ubiquitin-protein transferase activity);GO:0061630(ubiquitin protein ligase activity);GO:0051865(protein autoubiquitination)","NA","NA","NA","listerin E3 ubiquitin protein ligase 1 [Source:HGNC Symbol;Acc:HGNC:13082]",{"v":0.011375,"d":"0.01"},0,"inf","inf",1,1,"up","no"]
[89468,0,"chr17","-",81843166,81847327,"ENST00000415593",7,1669,"MSTRG.7333","P4HB","GO:0003723(RNA binding);GO:0016020(membrane);GO:0016853(isomerase activity);GO:0005783(endoplasmic reticulum);GO:0045454(cell redox homeostasis);GO:0005886(plasma membrane);GO:0055114(oxidation-reduction process);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0042470(melanosome);GO:0051213(dioxygenase activity);GO:0003756(protein disulfide isomerase activity);GO:0005178(integrin binding);GO:0019899(enzyme binding);GO:0046982(protein heterodimerization activity);GO:0009897(external side of plasma membrane);GO:0034663(endoplasmic reticulum chaperone complex);GO:0005925(focal adhesion);GO:0005788(endoplasmic reticulum lumen);GO:0070062(extracellular exosome);GO:0044267(cellular protein metabolic process);GO:0043687(post-translational protein modification);GO:0031012(extracellular matrix);GO:0035722(interleukin-12-mediated signaling pathway);GO:0046598(positive regulation of viral entry into host cell);GO:0034599(cellular response to oxidative stress);GO:0071456(cellular response to hypoxia);GO:0034976(response to endoplasmic reticulum stress);GO:0006457(protein folding);GO:0005793(endoplasmic reticulum-Golgi intermediate compartment);GO:0004656(procollagen-proline 4-dioxygenase activity);GO:0034378(chylomicron assembly);GO:0034379(very-low-density lipoprotein particle assembly);GO:0015037(peptide disulfide oxidoreductase activity);GO:0018401(peptidyl-proline hydroxylation to 4-hydroxy-L-proline);GO:1902175(regulation of oxidative stress-induced intrinsic apoptotic signaling pathway);GO:0016222(procollagen-proline 4-dioxygenase complex);GO:0005623(cell)","04141(Protein processing in endoplasmic reticulum)","NA","NA","prolyl 4-hydroxylase subunit beta [Source:HGNC Symbol;Acc:HGNC:8548]",{"v":0.077737,"d":"0.08"},{"v":0.112039,"d":"0.11"},{"v":0.693838752577228,"d":"0.69"},{"v":-0.527327673995474,"d":"-0.53"},1,1,"down","no"]
[76373,0,"chr16","+",84733209,84744911,"ENST00000563023",2,574,"MSTRG.6197","USP10","GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0016579(protein deubiquitination);GO:0016787(hydrolase activity);GO:0005515(protein binding);GO:0008233(peptidase activity);GO:0008234(cysteine-type peptidase activity);GO:0006508(proteolysis);GO:0006281(DNA repair);GO:0006974(cellular response to DNA damage stimulus);GO:0006511(ubiquitin-dependent protein catabolic process);GO:0036459(thiol-dependent ubiquitinyl hydrolase activity);GO:0006914(autophagy);GO:0005768(endosome);GO:0044325(ion channel binding);GO:0043234(protein complex);GO:0005769(early endosome);GO:0071347(cellular response to interleukin-1);GO:0004843(thiol-dependent ubiquitin-specific protease activity);GO:0010506(regulation of autophagy);GO:0043124(negative regulation of I-kappaB kinase/NF-kappaB signaling);GO:0019985(translesion synthesis);GO:0030330(DNA damage response, signal transduction by p53 class mediator);GO:0002039(p53 binding);GO:0004197(cysteine-type endopeptidase activity)","NA","NA","NA","ubiquitin specific peptidase 10 [Source:HGNC Symbol;Acc:HGNC:12608]",{"v":0.000123,"d":"0.00"},{"v":0.01827,"d":"0.02"},{"v":0.00673234811165846,"d":"0.01"},{"v":-7.21467450817561,"d":"-7.21"},1,1,"down","no"]
[197950,0,"chrX","+",68499034,68515340,"ENST00000470730",3,2267,"ENSG00000181704","YIPF6","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005515(protein binding);GO:0005783(endoplasmic reticulum);GO:0042802(identical protein binding);GO:0060576(intestinal epithelial cell development);GO:0005801(cis-Golgi network);GO:0005802(trans-Golgi network);GO:0030134(ER to Golgi transport vesicle)","NA","NA","NA","Yip1 domain family member 6 [Source:HGNC Symbol;Acc:HGNC:28304]",{"v":0.005949,"d":"0.01"},0,"inf","inf",1,1,"up","no"]
[12139,0,"chr1","+",156582427,156585841,"ENST00000478081",4,919,"ENSG00000187862","TTC24","NA","NA","NA","NA","tetratricopeptide repeat domain 24 [Source:HGNC Symbol;Acc:HGNC:32348]",{"v":0.432462,"d":"0.43"},{"v":0.457944,"d":"0.46"},{"v":0.944355641737854,"d":"0.94"},{"v":-0.082597817983866,"d":"-0.08"},1,1,"down","no"]
[84277,0,"chr17","-",44850810,44863595,"ENST00000586276",11,3678,"MSTRG.6910","EFTUD2","GO:0003723(RNA binding);GO:0006397(mRNA processing);GO:0008380(RNA splicing);GO:0005634(nucleus);GO:0016607(nuclear speck);GO:0016020(membrane);GO:0005525(GTP binding);GO:0000166(nucleotide binding);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0003924(GTPase activity);GO:0005515(protein binding);GO:0005681(spliceosomal complex);GO:0031012(extracellular matrix);GO:0000398(mRNA splicing, via spliceosome);GO:0015030(Cajal body);GO:0046540(U4/U6 x U5 tri-snRNP complex);GO:0071013(catalytic step 2 spliceosome);GO:0035690(cellular response to drug);GO:0042220(response to cocaine)","03040(Spliceosome)","NA","NA","elongation factor Tu GTP binding domain containing 2 [Source:HGNC Symbol;Acc:HGNC:30858]",{"v":0.019366,"d":"0.02"},{"v":0.013865,"d":"0.01"},{"v":1.39675441759827,"d":"1.40"},{"v":0.482078383196568,"d":"0.48"},1,1,"up","no"]
[18911,0,"chr10","-",18513115,18545651,"ENST00000425669",5,1028,"ENSG00000240291","AL450384.2","NA","NA","NA","NA","NA",{"v":0.387547,"d":"0.39"},{"v":0.420634,"d":"0.42"},{"v":0.921340167461498,"d":"0.92"},{"v":-0.118194183627859,"d":"-0.12"},1,1,"down","no"]
[25623,0,"chr11","-",3775894,3797552,"ENST00000532475",5,553,"MSTRG.2149","NUP98","GO:0006810(transport);GO:0051028(mRNA transport);GO:0005634(nucleus);GO:0016020(membrane);GO:0015031(protein transport);GO:0043231(intracellular membrane-bounded organelle);GO:0005654(nucleoplasm);GO:0016787(hydrolase activity);GO:0030529(intracellular ribonucleoprotein complex);GO:0005643(nuclear pore);GO:0008233(peptidase activity);GO:0006508(proteolysis);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0006260(DNA replication);GO:0008236(serine-type peptidase activity);GO:0000776(kinetochore);GO:0003729(mRNA binding);GO:0003723(RNA binding);GO:0005515(protein binding);GO:0005829(cytosol);GO:0075733(intracellular transport of virus);GO:0043657(host cell);GO:0016032(viral process);GO:0008139(nuclear localization sequence binding);GO:0007062(sister chromatid cohesion);GO:0031965(nuclear membrane);GO:0005215(transporter activity);GO:0005635(nuclear envelope);GO:0006406(mRNA export from nucleus);GO:0001105(RNA polymerase II transcription coactivator activity);GO:0016925(protein sumoylation);GO:0006606(protein import into nucleus);GO:0060964(regulation of gene silencing by miRNA);GO:0006110(regulation of glycolytic process);GO:0006409(tRNA export from nucleus);GO:0007077(mitotic nuclear envelope disassembly);GO:0019083(viral transcription);GO:1900034(regulation of cellular response to heat);GO:1990841(promoter-specific chromatin binding);GO:0006913(nucleocytoplasmic transport);GO:0016604(nuclear body);GO:0042405(nuclear inclusion body);GO:0006405(RNA export from nucleus);GO:0034399(nuclear periphery);GO:0006999(nuclear pore organization);GO:0044615(nuclear pore nuclear basket);GO:0048026(positive regulation of mRNA splicing, via spliceosome);GO:0005487(nucleocytoplasmic transporter activity);GO:0017056(structural constituent of nuclear pore);GO:0051292(nuclear pore complex assembly);GO:0044614(nuclear pore cytoplasmic filaments);GO:0042277(peptide binding);GO:0000973(posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery);GO:0034398(telomere tethering at nuclear periphery);GO:0031080(nuclear pore outer ring)","03013(RNA transport);05164(Influenza A)","NA","NA","nucleoporin 98 [Source:HGNC Symbol;Acc:HGNC:8068]",0,0,1,0,1,1,"no","no"]
[126435,0,"chr21","+",29193494,29288205,"ENST00000420364",2,989,"MSTRG.9981","LINC00189","NA","NA","NA","NA","long intergenic non-protein coding RNA 189 [Source:HGNC Symbol;Acc:HGNC:18461]",0,{"v":0.174941,"d":"0.17"},"-inf","-inf",1,1,"down","no"]
[76583,0,"chr16","-",87386011,87392142,"ENST00000567622",4,438,"MSTRG.6210","FBXO31","GO:0016567(protein ubiquitination);GO:0006974(cellular response to DNA damage stimulus);GO:0007049(cell cycle);GO:0030332(cyclin binding);GO:0031146(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process);GO:0031571(mitotic G1 DNA damage checkpoint);GO:0019005(SCF ubiquitin ligase complex);GO:0005829(cytosol);GO:0000209(protein polyubiquitination);GO:0043687(post-translational protein modification);GO:0031145(anaphase-promoting complex-dependent catabolic process);GO:0004842(ubiquitin-protein transferase activity);GO:0043025(neuronal cell body);GO:0050775(positive regulation of dendrite morphogenesis);GO:2001224(positive regulation of neuron migration);GO:0005813(centrosome);GO:0016020(membrane);GO:0016021(integral component of membrane)","NA","NA","NA","F-box protein 31 [Source:HGNC Symbol;Acc:HGNC:16510]",{"v":0.078703,"d":"0.08"},0,"inf","inf",1,1,"up","no"]
[45433,0,"chr12","-",95972662,95996365,"ENST00000541929",20,3846,"MSTRG.3623","HAL","GO:0005737(cytoplasm);GO:0003824(catalytic activity);GO:0016829(lyase activity);GO:0005829(cytosol);GO:0006548(histidine catabolic process);GO:0016841(ammonia-lyase activity);GO:0006547(histidine metabolic process);GO:0019556(histidine catabolic process to glutamate and formamide);GO:0019557(histidine catabolic process to glutamate and formate);GO:0004397(histidine ammonia-lyase activity)","00340(Histidine metabolism)","K01745","EC:4.3.1.3","histidine ammonia-lyase [Source:HGNC Symbol;Acc:HGNC:4806]",0,{"v":0.507422,"d":"0.51"},"-inf","-inf",1,1,"down","no"]
[172147,0,"chr7","+",18495739,18590354,"ENST00000476135",5,1115,"ENSG00000048052","HDAC9","GO:0005737(cytoplasm);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0004407(histone deacetylase activity);GO:0016787(hydrolase activity);GO:0032041(NAD-dependent histone deacetylase activity (H3-K14 specific));GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0016569(covalent chromatin modification);GO:0005515(protein binding);GO:0006325(chromatin organization);GO:0006954(inflammatory response);GO:0005654(nucleoplasm);GO:0016575(histone deacetylation);GO:0042113(B cell activation);GO:0000118(histone deacetylase complex);GO:0005667(transcription factor complex);GO:0008134(transcription factor binding);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0045892(negative regulation of transcription, DNA-templated);GO:0007507(heart development);GO:0035097(histone methyltransferase complex);GO:0042826(histone deacetylase binding);GO:0032869(cellular response to insulin stimulus);GO:0003714(transcription corepressor activity);GO:0030183(B cell differentiation);GO:0005080(protein kinase C binding);GO:0090050(positive regulation of cell migration involved in sprouting angiogenesis);GO:0070491(repressing transcription factor binding);GO:0033558(protein deacetylase activity);GO:0034983(peptidyl-lysine deacetylation);GO:0070932(histone H3 deacetylation);GO:0070933(histone H4 deacetylation);GO:0048742(regulation of skeletal muscle fiber development);GO:0051153(regulation of striated muscle cell differentiation);GO:0001975(response to amphetamine);GO:0030182(neuron differentiation)","05203(Viral carcinogenesis);05034(Alcoholism);05165(Human papillomavirus infection)","NA","NA","histone deacetylase 9 [Source:HGNC Symbol;Acc:HGNC:14065]",0,0,1,0,1,1,"no","no"]
[84070,0,"chr17","-",44091293,44093505,"ENST00000587776",6,917,"MSTRG.6884","HDAC5","GO:0051091(positive regulation of sequence-specific DNA binding transcription factor activity);GO:0010832(negative regulation of myotube differentiation);GO:0090051(negative regulation of cell migration involved in sprouting angiogenesis);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0005737(cytoplasm);GO:0005634(nucleus);GO:0016607(nuclear speck);GO:0005794(Golgi apparatus);GO:0046872(metal ion binding);GO:0005829(cytosol);GO:0004407(histone deacetylase activity);GO:0016787(hydrolase activity);GO:0032041(NAD-dependent histone deacetylase activity (H3-K14 specific));GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0016569(covalent chromatin modification);GO:0070932(histone H3 deacetylation);GO:0006476(protein deacetylation);GO:0005515(protein binding);GO:0006325(chromatin organization);GO:0006954(inflammatory response);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0001047(core promoter binding);GO:0005654(nucleoplasm);GO:0016575(histone deacetylation);GO:0042113(B cell activation);GO:0000118(histone deacetylase complex);GO:0040029(regulation of gene expression, epigenetic);GO:0045892(negative regulation of transcription, DNA-templated);GO:0044212(transcription regulatory region DNA binding);GO:0008134(transcription factor binding);GO:0033558(protein deacetylase activity);GO:0042826(histone deacetylase binding);GO:0032869(cellular response to insulin stimulus);GO:0006338(chromatin remodeling);GO:0030183(B cell differentiation);GO:0005080(protein kinase C binding);GO:0043393(regulation of protein binding);GO:0070491(repressing transcription factor binding);GO:0001025(RNA polymerase III transcription factor binding);GO:0010830(regulation of myotube differentiation);GO:0006342(chromatin silencing);GO:0003682(chromatin binding);GO:0014823(response to activity);GO:0030182(neuron differentiation);GO:0042220(response to cocaine);GO:0042493(response to drug);GO:0071222(cellular response to lipopolysaccharide);GO:0043234(protein complex)","04371(Apelin signaling pathway);05203(Viral carcinogenesis);05034(Alcoholism);05169(Epstein-Barr virus infection);05165(Human papillomavirus infection)","NA","NA","histone deacetylase 5 [Source:HGNC Symbol;Acc:HGNC:14068]",{"v":0.043222,"d":"0.04"},{"v":0.031492,"d":"0.03"},{"v":1.37247554934587,"d":"1.37"},{"v":0.456780447844918,"d":"0.46"},1,1,"up","no"]
[169200,0,"chr6","+",131628442,131676797,"ENST00000427707",12,1536,"ENSG00000154269","ENPP3","GO:0048471(perinuclear region of cytoplasm);GO:0003676(nucleic acid binding);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0046872(metal ion binding);GO:0016787(hydrolase activity);GO:0003824(catalytic activity);GO:0008152(metabolic process);GO:0090305(nucleic acid phosphodiester bond hydrolysis);GO:0005576(extracellular region);GO:0006955(immune response);GO:0005044(scavenger receptor activity);GO:0006898(receptor-mediated endocytosis);GO:0004551(nucleotide diphosphatase activity);GO:0035529(NADH pyrophosphatase activity);GO:0030247(polysaccharide binding);GO:0070062(extracellular exosome);GO:0005887(integral component of plasma membrane);GO:0004528(phosphodiesterase I activity);GO:0047429(nucleoside-triphosphate diphosphatase activity);GO:0006796(phosphate-containing compound metabolic process);GO:0009143(nucleoside triphosphate catabolic process)","00500(Starch and sucrose metabolism);00230(Purine metabolism);00240(Pyrimidine metabolism);00740(Riboflavin metabolism);00760(Nicotinate and nicotinamide metabolism);00770(Pantothenate and CoA biosynthesis)","NA","NA","ectonucleotide pyrophosphatase/phosphodiesterase 3 [Source:HGNC Symbol;Acc:HGNC:3358]",0,{"v":0.134312,"d":"0.13"},"-inf","-inf",1,1,"down","no"]
[118974,0,"chr2","+",218125705,218134846,"ENST00000449014",4,262,"MSTRG.9411","CXCR2","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0004930(G-protein coupled receptor activity);GO:0007186(G-protein coupled receptor signaling pathway);GO:0004871(signal transducer activity);GO:0007165(signal transduction);GO:0006935(chemotaxis);GO:0070098(chemokine-mediated signaling pathway);GO:0016494(C-X-C chemokine receptor activity);GO:0019959(interleukin-8 binding);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0005887(integral component of plasma membrane);GO:0030593(neutrophil chemotaxis);GO:0005622(intracellular);GO:0043312(neutrophil degranulation);GO:0008284(positive regulation of cell proliferation);GO:0006954(inflammatory response);GO:0009986(cell surface);GO:0030667(secretory granule membrane);GO:0002407(dendritic cell chemotaxis);GO:0006968(cellular defense response);GO:0031623(receptor internalization);GO:0007166(cell surface receptor signaling pathway);GO:0007200(phospholipase C-activating G-protein coupled receptor signaling pathway);GO:0042629(mast cell granule);GO:0042119(neutrophil activation);GO:0004918(interleukin-8 receptor activity);GO:0038112(interleukin-8-mediated signaling pathway)","04072(Phospholipase D signaling pathway);04060(Cytokine-cytokine receptor interaction);04144(Endocytosis);04062(Chemokine signaling pathway);05120(Epithelial cell signaling in Helicobacter pylori infection)","NA","NA","C-X-C motif chemokine receptor 2 [Source:HGNC Symbol;Acc:HGNC:6027]",{"v":2.413985,"d":"2.41"},{"v":1.222457,"d":"1.22"},{"v":1.97469931457712,"d":"1.97"},{"v":0.981632992330894,"d":"0.98"},1,1,"up","no"]
[97810,0,"chr19","-",15468645,15479501,"ENST00000292609",4,2758,"ENSG00000161031","PGLYRP2","GO:0016020(membrane);GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0016787(hydrolase activity);GO:0005576(extracellular region);GO:0002376(immune system process);GO:0045087(innate immune response);GO:0070062(extracellular exosome);GO:0005622(intracellular);GO:0002221(pattern recognition receptor signaling pathway);GO:0050830(defense response to Gram-positive bacterium);GO:0009253(peptidoglycan catabolic process);GO:0019730(antimicrobial humoral response);GO:0042834(peptidoglycan binding);GO:0008745(N-acetylmuramoyl-L-alanine amidase activity);GO:0016019(peptidoglycan receptor activity);GO:0016045(detection of bacterium);GO:0001519(peptide amidation);GO:0032689(negative regulation of interferon-gamma production);GO:0032827(negative regulation of natural killer cell differentiation involved in immune response);GO:0044117(growth of symbiont in host);GO:0050727(regulation of inflammatory response)","NA","NA","NA","peptidoglycan recognition protein 2 [Source:HGNC Symbol;Acc:HGNC:30013]",{"v":0.03852,"d":"0.04"},{"v":0.055113,"d":"0.06"},{"v":0.698927657721409,"d":"0.70"},{"v":-0.516784957237529,"d":"-0.52"},1,1,"down","no"]
[176621,0,"chr7","-",99658833,99663582,"ENST00000473347",2,2594,"ENSG00000106258","CYP3A5","GO:0016020(membrane);GO:0046872(metal ion binding);GO:0004497(monooxygenase activity);GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005506(iron ion binding);GO:0016705(oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen);GO:0020037(heme binding);GO:0016712(oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen);GO:0070330(aromatase activity);GO:0043231(intracellular membrane-bounded organelle);GO:0006805(xenobiotic metabolic process);GO:0031090(organelle membrane);GO:0019825(oxygen binding);GO:0008202(steroid metabolic process);GO:0101020(estrogen 16-alpha-hydroxylase activity);GO:0002933(lipid hydroxylation);GO:0042737(drug catabolic process);GO:0070989(oxidative demethylation);GO:0009822(alkaloid catabolic process);GO:0016021(integral component of membrane)","00140(Steroid hormone biosynthesis);00830(Retinol metabolism);00980(Metabolism of xenobiotics by cytochrome P450);00982(Drug metabolism - cytochrome P450);05204(Chemical carcinogenesis)","NA","NA","cytochrome P450 family 3 subfamily A member 5 [Source:HGNC Symbol;Acc:HGNC:2638]",0,0,1,0,1,1,"no","no"]
[157967,0,"chr5","+",127290859,127461222,"ENST00000274473",26,7594,"ENSG00000145794","MEGF10","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0007155(cell adhesion);GO:0005886(plasma membrane);GO:0042995(cell projection);GO:0006898(receptor-mediated endocytosis);GO:0001891(phagocytic cup);GO:0034109(homotypic cell-cell adhesion);GO:0016323(basolateral plasma membrane);GO:0007517(muscle organ development);GO:0006909(phagocytosis);GO:0005112(Notch binding);GO:0043652(engulfment of apoptotic cell);GO:0051451(myoblast migration);GO:1902742(apoptotic process involved in development);GO:0051147(regulation of muscle cell differentiation);GO:0014719(skeletal muscle satellite cell activation);GO:0001849(complement component C1q binding);GO:0005044(scavenger receptor activity);GO:0014816(skeletal muscle satellite cell differentiation);GO:0014841(skeletal muscle satellite cell proliferation);GO:0033002(muscle cell proliferation);GO:0048641(regulation of skeletal muscle tissue development);GO:0055001(muscle cell development);GO:0043654(recognition of apoptotic cell)","NA","NA","NA","multiple EGF like domains 10 [Source:HGNC Symbol;Acc:HGNC:29634]",0,0,1,0,1,1,"no","no"]
[139646,0,"chr3","-",121795461,121835033,"ENST00000460108",9,988,"ENSG00000173226","IQCB1","GO:0005737(cytoplasm);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0060271(cilium assembly);GO:0005516(calmodulin binding);GO:0005813(centrosome);GO:0005815(microtubule organizing center);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0030030(cell projection organization);GO:0005814(centriole);GO:0097711(ciliary basal body docking);GO:0019899(enzyme binding);GO:0045494(photoreceptor cell maintenance);GO:0048496(maintenance of animal organ identity);GO:0001750(photoreceptor outer segment);GO:0032391(photoreceptor connecting cilium)","NA","NA","NA","IQ motif containing B1 [Source:HGNC Symbol;Acc:HGNC:28949]",{"v":0.057883,"d":"0.06"},{"v":0.064592,"d":"0.06"},{"v":0.896132648005945,"d":"0.90"},{"v":-0.158215795131201,"d":"-0.16"},1,1,"down","no"]
[83051,0,"chr17","+",40123097,40126860,"ENST00000578826",2,962,"MSTRG.6793","MSL1","GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0016569(covalent chromatin modification);GO:0043984(histone H4-K16 acetylation);GO:0072487(MSL complex)","NA","NA","NA","male specific lethal 1 homolog [Source:HGNC Symbol;Acc:HGNC:27905]",{"v":0.262404,"d":"0.26"},{"v":0.095791,"d":"0.10"},{"v":2.73933876877786,"d":"2.74"},{"v":1.45382769240832,"d":"1.45"},1,1,"up","no"]
[5351,0,"chr1","+",44739820,44767767,"ENST00000372224",21,2879,"MSTRG.512","KIF2C","GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0003777(microtubule motor activity);GO:0008017(microtubule binding);GO:0003774(motor activity);GO:0007018(microtubule-based movement);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0051301(cell division);GO:0005694(chromosome);GO:0005813(centrosome);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0007049(cell cycle);GO:0005874(microtubule);GO:0007059(chromosome segregation);GO:0000775(chromosome, centromeric region);GO:0000776(kinetochore);GO:0000777(condensed chromosome kinetochore);GO:0006890(retrograde vesicle-mediated transport, Golgi to ER);GO:0016887(ATPase activity);GO:0007062(sister chromatid cohesion);GO:0019886(antigen processing and presentation of exogenous peptide antigen via MHC class II);GO:0008283(cell proliferation);GO:0000278(mitotic cell cycle);GO:0051310(metaphase plate congression);GO:0051315(attachment of mitotic spindle microtubules to kinetochore);GO:0005871(kinesin complex);GO:0005881(cytoplasmic microtubule);GO:0019237(centromeric DNA binding);GO:0007080(mitotic metaphase plate congression);GO:0051983(regulation of chromosome segregation);GO:0051010(microtubule plus-end binding);GO:0015630(microtubule cytoskeleton);GO:0035371(microtubule plus-end);GO:0030951(establishment or maintenance of microtubule cytoskeleton polarity);GO:0007019(microtubule depolymerization)","NA","NA","NA","kinesin family member 2C [Source:HGNC Symbol;Acc:HGNC:6393]",0,{"v":0.283842,"d":"0.28"},"-inf","-inf",1,1,"down","no"]
[61603,0,"chr15","+",42515237,42545356,"ENST00000563830",4,570,"MSTRG.5013","SNAP23","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0006810(transport);GO:0005737(cytoplasm);GO:0015031(protein transport);GO:0005654(nucleoplasm);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0030054(cell junction);GO:0045202(synapse);GO:0098793(presynapse);GO:0005925(focal adhesion);GO:0042629(mast cell granule);GO:0070062(extracellular exosome);GO:0002479(antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent);GO:0043312(neutrophil degranulation);GO:0035579(specific granule membrane);GO:0070821(tertiary granule membrane);GO:0005484(SNAP receptor activity);GO:0005913(cell-cell adherens junction);GO:0019905(syntaxin binding);GO:0002553(histamine secretion by mast cell);GO:0006892(post-Golgi vesicle-mediated transport);GO:0006903(vesicle targeting);GO:0016082(synaptic vesicle priming);GO:0031629(synaptic vesicle fusion to presynaptic active zone membrane);GO:0061025(membrane fusion);GO:0030670(phagocytic vesicle membrane);GO:0031201(SNARE complex);GO:0042581(specific granule);GO:0042582(azurophil granule);GO:0043005(neuron projection)","04130(SNARE interactions in vesicular transport);04611(Platelet activation)","NA","NA","synaptosome associated protein 23 [Source:HGNC Symbol;Acc:HGNC:11131]",{"v":9.019423,"d":"9.02"},{"v":1.083576,"d":"1.08"},{"v":8.32375670926635,"d":"8.32"},{"v":3.0572347979103,"d":"3.06"},1,1,"up","no"]
[197336,0,"chrX","+",51893649,51902354,"ENST00000494718",6,5418,"ENSG00000179222","MAGED1","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0006355(regulation of transcription, DNA-templated);GO:0042981(regulation of apoptotic process);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0048511(rhythmic process);GO:0042802(identical protein binding);GO:0032922(circadian regulation of gene expression);GO:0043234(protein complex);GO:0000785(chromatin);GO:0050680(negative regulation of epithelial cell proliferation);GO:0003713(transcription coactivator activity);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0042752(regulation of circadian rhythm);GO:0043406(positive regulation of MAP kinase activity);GO:0045892(negative regulation of transcription, DNA-templated);GO:0045893(positive regulation of transcription, DNA-templated);GO:0090190(positive regulation of branching involved in ureteric bud morphogenesis);GO:2001235(positive regulation of apoptotic signaling pathway)","04722(Neurotrophin signaling pathway)","NA","NA","MAGE family member D1 [Source:HGNC Symbol;Acc:HGNC:6813]",{"v":0.000865,"d":"0.00"},{"v":0.038078,"d":"0.04"},{"v":0.0227165292294763,"d":"0.02"},{"v":-5.46011376188298,"d":"-5.46"},1,1,"down","no"]
[62615,0,"chr15","-",51919073,51930627,"ENST00000557871",9,1041,"MSTRG.5087","AC090971.3","NA","NA","NA","NA","NA",{"v":0.101943,"d":"0.10"},{"v":0.048172,"d":"0.05"},{"v":2.11622934484763,"d":"2.12"},{"v":1.08149598697204,"d":"1.08"},1,1,"up","no"]
[17799,0,"chr1","+",247920252,247921956,"ENST00000641945",2,1226,"ENSG00000177462","OR2T8","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0004930(G-protein coupled receptor activity);GO:0007186(G-protein coupled receptor signaling pathway);GO:0005886(plasma membrane);GO:0004871(signal transducer activity);GO:0007165(signal transduction);GO:0004984(olfactory receptor activity);GO:0007608(sensory perception of smell);GO:0050896(response to stimulus);GO:0050911(detection of chemical stimulus involved in sensory perception of smell)","04740(Olfactory transduction)","K04257","NA","olfactory receptor family 2 subfamily T member 8 [Source:HGNC Symbol;Acc:HGNC:15020]",0,{"v":4.6E-5,"d":"0.00"},"-inf","-inf",1,1,"down","no"]
[78424,0,"chr17","+",6651718,6653473,"ENST00000542475",1,1756,"MSTRG.6371","C17orf100","NA","NA","NA","NA","chromosome 17 open reading frame 100 [Source:HGNC Symbol;Acc:HGNC:34494]",0,0,1,0,1,1,"no","no"]
[161772,0,"chr5","-",178153222,178153884,"ENST00000510363",2,566,"MSTRG.12587","NHP2","GO:0003723(RNA binding);GO:0005634(nucleus);GO:0030529(intracellular ribonucleoprotein complex);GO:0005515(protein binding);GO:0005730(nucleolus);GO:0042254(ribosome biogenesis);GO:0006364(rRNA processing);GO:0005654(nucleoplasm);GO:0000784(nuclear chromosome, telomeric region);GO:0005732(small nucleolar ribonucleoprotein complex);GO:0070034(telomerase RNA binding);GO:0007004(telomere maintenance via telomerase);GO:0005697(telomerase holoenzyme complex);GO:0015030(Cajal body);GO:0006412(translation);GO:0034513(box H/ACA snoRNA binding);GO:0031118(rRNA pseudouridine synthesis);GO:0031120(snRNA pseudouridine synthesis);GO:1904874(positive regulation of telomerase RNA localization to Cajal body);GO:0031429(box H/ACA snoRNP complex);GO:0072589(box H/ACA scaRNP complex);GO:0090661(box H/ACA telomerase RNP complex);GO:0000470(maturation of LSU-rRNA);GO:0030515(snoRNA binding);GO:0000469(cleavage involved in rRNA processing)","03008(Ribosome biogenesis in eukaryotes)","NA","NA","NHP2 ribonucleoprotein [Source:HGNC Symbol;Acc:HGNC:14377]",{"v":0.044134,"d":"0.04"},{"v":0.049964,"d":"0.05"},{"v":0.883315987511008,"d":"0.88"},{"v":-0.178998471208589,"d":"-0.18"},1,1,"down","no"]
[132593,"p","chr22",".",50541776,50541980,"MSTRG.10607.1",1,205,"MSTRG.10607","U62317.2","NA","NA","NA","NA","NA",{"v":0.481347,"d":"0.48"},{"v":1.498559,"d":"1.50"},{"v":0.321206572447264,"d":"0.32"},{"v":-1.63842668167079,"d":"-1.64"},1,1,"down","no"]
[109180,0,"chr2","-",42767120,42792574,"ENST00000402698",9,1522,"ENSG00000162882","HAAO","GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0005829(cytosol);GO:0005506(iron ion binding);GO:0005515(protein binding);GO:0009435(NAD biosynthetic process);GO:0019363(pyridine nucleotide biosynthetic process);GO:0051213(dioxygenase activity);GO:0070062(extracellular exosome);GO:0000334(3-hydroxyanthranilate 3,4-dioxygenase activity);GO:0009055(electron carrier activity);GO:0006569(tryptophan catabolic process);GO:0008198(ferrous iron binding);GO:0010043(response to zinc ion);GO:0019805(quinolinate biosynthetic process);GO:0046686(response to cadmium ion);GO:0070050(neuron cellular homeostasis)","00380(Tryptophan metabolism)","NA","NA","3-hydroxyanthranilate 3,4-dioxygenase [Source:HGNC Symbol;Acc:HGNC:4796]",0,{"v":0.445326,"d":"0.45"},"-inf","-inf",1,1,"down","no"]
[121134,0,"chr2","+",241350087,241352626,"ENST00000451310",2,801,"MSTRG.9533","SEPT2","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005525(GTP binding);GO:0000166(nucleotide binding);GO:0005730(nucleolus);GO:0005829(cytosol);GO:0051301(cell division);GO:0005694(chromosome);GO:0005886(plasma membrane);GO:0015629(actin cytoskeleton);GO:0005856(cytoskeleton);GO:0042995(cell projection);GO:0005515(protein binding);GO:0007049(cell cycle);GO:0030154(cell differentiation);GO:0007283(spermatogenesis);GO:0005819(spindle);GO:0030496(midbody);GO:0000775(chromosome, centromeric region);GO:0000776(kinetochore);GO:0000777(condensed chromosome kinetochore);GO:0007224(smoothened signaling pathway);GO:0060271(cilium assembly);GO:0045296(cadherin binding);GO:0070062(extracellular exosome);GO:0005938(cell cortex);GO:0032154(cleavage furrow);GO:0060170(ciliary membrane);GO:0031105(septin complex);GO:0097227(sperm annulus);GO:0005930(axoneme);GO:0032391(photoreceptor connecting cilium);GO:0097730(non-motile cilium);GO:0031175(neuron projection development);GO:0000145(exocyst);GO:0048471(perinuclear region of cytoplasm)","05100(Bacterial invasion of epithelial cells)","NA","NA","septin 2 [Source:HGNC Symbol;Acc:HGNC:7729]",{"v":1.698025,"d":"1.70"},{"v":0.797333,"d":"0.80"},{"v":2.12963090703633,"d":"2.13"},{"v":1.09060341414629,"d":"1.09"},1,1,"up","no"]
[63877,0,"chr15","+",67166019,67190762,"ENST00000537194",7,1147,"MSTRG.5211","SMAD3","GO:0006355(regulation of transcription, DNA-templated);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0005622(intracellular);GO:0007179(transforming growth factor beta receptor signaling pathway);GO:0005667(transcription factor complex);GO:0010628(positive regulation of gene expression);GO:0045599(negative regulation of fat cell differentiation);GO:0010718(positive regulation of epithelial to mesenchymal transition);GO:0006919(activation of cysteine-type endopeptidase activity involved in apoptotic process);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0005737(cytoplasm);GO:0005634(nucleus);GO:0045930(negative regulation of mitotic cell cycle);GO:0046872(metal ion binding);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0008270(zinc ion binding);GO:0005515(protein binding);GO:0000977(RNA polymerase II regulatory region sequence-specific DNA binding);GO:0003682(chromatin binding);GO:0003690(double-stranded DNA binding);GO:0005518(collagen binding);GO:0008013(beta-catenin binding);GO:0008134(transcription factor binding);GO:0019899(enzyme binding);GO:0031490(chromatin DNA binding);GO:0042803(protein homodimerization activity);GO:0043565(sequence-specific DNA binding);GO:0046332(SMAD binding);GO:0046982(protein heterodimerization activity);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0001501(skeletal system development);GO:0001649(osteoblast differentiation);GO:0001657(ureteric bud development);GO:0001701(in utero embryonic development);GO:0001707(mesoderm formation);GO:0001756(somitogenesis);GO:0001889(liver development);GO:0001947(heart looping);GO:0002076(osteoblast development);GO:0002520(immune system development);GO:0007183(SMAD protein complex assembly);GO:0007369(gastrulation);GO:0007492(endoderm development);GO:0008285(negative regulation of cell proliferation);GO:0009880(embryonic pattern specification);GO:0010694(positive regulation of alkaline phosphatase activity);GO:0016202(regulation of striated muscle tissue development);GO:0017015(regulation of transforming growth factor beta receptor signaling pathway);GO:0023019(signal transduction involved in regulation of gene expression);GO:0030335(positive regulation of cell migration);GO:0030501(positive regulation of bone mineralization);GO:0030878(thyroid gland development);GO:0032332(positive regulation of chondrocyte differentiation);GO:0032731(positive regulation of interleukin-1 beta production);GO:0032916(positive regulation of transforming growth factor beta3 production);GO:0033689(negative regulation of osteoblast proliferation);GO:0035413(positive regulation of catenin import into nucleus);GO:0042110(T cell activation);GO:0042177(negative regulation of protein catabolic process);GO:0043066(negative regulation of apoptotic process);GO:0045429(positive regulation of nitric oxide biosynthetic process);GO:0045668(negative regulation of osteoblast differentiation);GO:0045893(positive regulation of transcription, DNA-templated);GO:0048340(paraxial mesoderm morphogenesis);GO:0048589(developmental growth);GO:0048617(embryonic foregut morphogenesis);GO:0048701(embryonic cranial skeleton morphogenesis);GO:0050678(regulation of epithelial cell proliferation);GO:0050728(negative regulation of inflammatory response);GO:0050776(regulation of immune response);GO:0050821(protein stabilization);GO:0050927(positive regulation of positive chemotaxis);GO:0051098(regulation of binding);GO:0051496(positive regulation of stress fiber assembly);GO:0051894(positive regulation of focal adhesion assembly);GO:0060039(pericardium development);GO:0060070(canonical Wnt signaling pathway);GO:0060290(transdifferentiation);GO:0060395(SMAD protein signal transduction);GO:0061045(negative regulation of wound healing);GO:0061767(negative regulation of lung blood pressure);GO:0070306(lens fiber cell differentiation);GO:0097296(activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway);GO:1903243(negative regulation of cardiac muscle hypertrophy in response to stress);GO:0005886(plasma membrane);GO:0043234(protein complex);GO:0042802(identical protein binding);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:0005637(nuclear inner membrane);GO:0019901(protein kinase binding);GO:0016579(protein deubiquitination);GO:0019902(phosphatase binding);GO:0043130(ubiquitin binding);GO:0043425(bHLH transcription factor binding);GO:0070412(R-SMAD binding);GO:0000790(nuclear chromatin);GO:0044212(transcription regulatory region DNA binding);GO:0070410(co-SMAD binding);GO:0001102(RNA polymerase II activating transcription factor binding);GO:1902895(positive regulation of pri-miRNA transcription from RNA polymerase II promoter);GO:0043235(receptor complex);GO:0031625(ubiquitin protein ligase binding);GO:0030512(negative regulation of transforming growth factor beta receptor signaling pathway);GO:0030618(transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity);GO:0097191(extrinsic apoptotic signaling pathway);GO:0000987(core promoter proximal region sequence-specific DNA binding);GO:0030308(negative regulation of cell growth);GO:0006955(immune response);GO:0000983(transcription factor activity, RNA polymerase II core promoter sequence-specific);GO:0035326(enhancer binding);GO:0032924(activin receptor signaling pathway);GO:0042993(positive regulation of transcription factor import into nucleus);GO:0007050(cell cycle arrest);GO:0019049(evasion or tolerance of host defenses by virus);GO:0045216(cell-cell junction organization);GO:1901203(positive regulation of extracellular matrix assembly);GO:0042060(wound healing);GO:0071560(cellular response to transforming growth factor beta stimulus);GO:0001666(response to hypoxia);GO:0070878(primary miRNA binding);GO:0051481(negative regulation of cytosolic calcium ion concentration);GO:0071141(SMAD protein complex);GO:0005160(transforming growth factor beta receptor binding);GO:0032909(regulation of transforming growth factor beta2 production);GO:0035259(glucocorticoid receptor binding);GO:0000988(transcription factor activity, protein binding);GO:0017151(DEAD/H-box RNA helicase binding);GO:0031962(mineralocorticoid receptor binding);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0006810(transport);GO:0031053(primary miRNA processing);GO:0038092(nodal signaling pathway);GO:0071144(SMAD2-SMAD3 protein complex)","04310(Wnt signaling pathway);04350(TGF-beta signaling pathway);04390(Hippo signaling pathway);04371(Apelin signaling pathway);04068(FoxO signaling pathway);04144(Endocytosis);04110(Cell cycle);04218(Cellular senescence);04520(Adherens junction);04550(Signaling pathways regulating pluripotency of stem cells);04659(Th17 cell differentiation);04926(Relaxin signaling pathway);05200(Pathways in cancer);05210(Colorectal cancer);05212(Pancreatic cancer);05225(Hepatocellular carcinoma);05226(Gastric cancer);05220(Chronic myeloid leukemia);05321(Inflammatiory bowel disease (IBD));04933(AGE-RAGE signaling pathway in diabetic complications);05166(HTLV-I infection);05161(Hepatitis B);05142(Chagas disease (American trypanosomiasis))","K04500","NA","SMAD family member 3 [Source:HGNC Symbol;Acc:HGNC:6769]",{"v":0.005981,"d":"0.01"},0,"inf","inf",1,1,"up","no"]
[132295,0,"chr22","+",46335745,46357184,"ENST00000381019",10,1381,"ENSG00000100416","TRMU","GO:0008168(methyltransferase activity);GO:0016740(transferase activity);GO:0008033(tRNA processing);GO:0032259(methylation);GO:0003723(RNA binding);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0005654(nucleoplasm);GO:0005739(mitochondrion);GO:0000049(tRNA binding);GO:0016783(sulfurtransferase activity);GO:0002143(tRNA wobble position uridine thiolation);GO:0070903(mitochondrial tRNA thio-modification)","NA","NA","NA","tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase [Source:HGNC Symbol;Acc:HGNC:25481]",0,{"v":0.06283,"d":"0.06"},"-inf","-inf",1,1,"down","no"]
[88777,0,"chr17","+",78202509,78207202,"ENST00000587750",4,541,"ENSG00000183077","AFMID","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016787(hydrolase activity);GO:0008152(metabolic process);GO:0005829(cytosol);GO:0019441(tryptophan catabolic process to kynurenine);GO:0006569(tryptophan catabolic process);GO:0004061(arylformamidase activity)","00630(Glyoxylate and dicarboxylate metabolism);00380(Tryptophan metabolism)","NA","NA","arylformamidase [Source:HGNC Symbol;Acc:HGNC:20910]",{"v":0.262878,"d":"0.26"},{"v":0.579007,"d":"0.58"},{"v":0.454015236430648,"d":"0.45"},{"v":-1.13918738073221,"d":"-1.14"},1,1,"down","no"]
[140227,0,"chr3","-",128486148,128490648,"ENST00000492608",3,844,"ENSG00000179348","GATA2","GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0005634(nucleus);GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0005654(nucleoplasm);GO:0006355(regulation of transcription, DNA-templated);GO:0006366(transcription from RNA polymerase II promoter);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0043565(sequence-specific DNA binding);GO:0005515(protein binding);GO:0030097(hemopoiesis);GO:1902036(regulation of hematopoietic stem cell differentiation);GO:0005667(transcription factor complex);GO:0000977(RNA polymerase II regulatory region sequence-specific DNA binding);GO:0001228(transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding);GO:0006909(phagocytosis);GO:0050766(positive regulation of phagocytosis);GO:0045599(negative regulation of fat cell differentiation);GO:0070345(negative regulation of fat cell proliferation);GO:0007596(blood coagulation);GO:0003682(chromatin binding);GO:0008134(transcription factor binding);GO:0045766(positive regulation of angiogenesis);GO:0001085(RNA polymerase II transcription factor binding);GO:0070742(C2H2 zinc finger domain binding);GO:0035854(eosinophil fate commitment);GO:0000979(RNA polymerase II core promoter sequence-specific DNA binding);GO:0000980(RNA polymerase II distal enhancer sequence-specific DNA binding);GO:0001077(transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0001158(enhancer sequence-specific DNA binding);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0001655(urogenital system development);GO:0001709(cell fate determination);GO:0001764(neuron migration);GO:0001892(embryonic placenta development);GO:0007204(positive regulation of cytosolic calcium ion concentration);GO:0010725(regulation of primitive erythrocyte differentiation);GO:0021514(ventral spinal cord interneuron differentiation);GO:0021533(cell differentiation in hindbrain);GO:0021902(commitment of neuronal cell to specific neuron type in forebrain);GO:0021954(central nervous system neuron development);GO:0021983(pituitary gland development);GO:0030154(cell differentiation);GO:0030182(neuron differentiation);GO:0033993(response to lipid);GO:0035019(somatic stem cell population maintenance);GO:0035065(regulation of histone acetylation);GO:0042472(inner ear morphogenesis);GO:0043306(positive regulation of mast cell degranulation);GO:0045638(negative regulation of myeloid cell differentiation);GO:0045648(positive regulation of erythrocyte differentiation);GO:0045650(negative regulation of macrophage differentiation);GO:0045654(positive regulation of megakaryocyte differentiation);GO:0045666(positive regulation of neuron differentiation);GO:0045746(negative regulation of Notch signaling pathway);GO:0048469(cell maturation);GO:0048663(neuron fate commitment);GO:0048873(homeostasis of number of cells within a tissue);GO:0060100(positive regulation of phagocytosis, engulfment);GO:0060216(definitive hemopoiesis);GO:0060872(semicircular canal development);GO:0090102(cochlea development);GO:0097154(GABAergic neuron differentiation);GO:2000178(negative regulation of neural precursor cell proliferation);GO:2000977(regulation of forebrain neuron differentiation);GO:0043234(protein complex)","NA","NA","NA","GATA binding protein 2 [Source:HGNC Symbol;Acc:HGNC:4171]",0,0,1,0,1,1,"no","no"]
[158803,0,"chr5","+",138424135,138425857,"ENST00000505756",2,654,"MSTRG.12353","KDM3B","GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0016569(covalent chromatin modification);GO:0051213(dioxygenase activity);GO:0098869(cellular oxidant detoxification);GO:0005654(nucleoplasm);GO:0000976(transcription regulatory region sequence-specific DNA binding);GO:0032452(histone demethylase activity);GO:0000785(chromatin);GO:0031490(chromatin DNA binding);GO:0032454(histone demethylase activity (H3-K9 specific));GO:0033169(histone H3-K9 demethylation);GO:0016209(antioxidant activity);GO:0072718(response to cisplatin)","NA","NA","NA","lysine demethylase 3B [Source:HGNC Symbol;Acc:HGNC:1337]",{"v":0.428273,"d":"0.43"},{"v":0.818656,"d":"0.82"},{"v":0.523141588164015,"d":"0.52"},{"v":-0.934726630447728,"d":"-0.93"},1,1,"down","no"]
[48047,0,"chr12","+",123364953,123366113,"ENST00000543072",2,752,"MSTRG.3835","AC137767.1","NA","NA","NA","NA","NA",{"v":0.252402,"d":"0.25"},{"v":0.082017,"d":"0.08"},{"v":3.07743516588024,"d":"3.08"},{"v":1.62172846293286,"d":"1.62"},1,1,"up","no"]
[33753,0,"chr11","-",83486155,83724956,"ENST00000530800",5,566,"ENSG00000150672","DLG2","GO:0016020(membrane);GO:0005886(plasma membrane);GO:0042995(cell projection);GO:0005515(protein binding);GO:0030054(cell junction);GO:0045202(synapse);GO:0045211(postsynaptic membrane);GO:0030424(axon);GO:0005829(cytosol);GO:0007399(nervous system development);GO:0014069(postsynaptic density);GO:0010923(negative regulation of phosphatase activity);GO:0046037(GMP metabolic process);GO:0046710(GDP metabolic process);GO:0007268(chemical synaptic transmission);GO:0004385(guanylate kinase activity);GO:0008076(voltage-gated potassium channel complex);GO:0019900(kinase binding);GO:0008328(ionotropic glutamate receptor complex);GO:0035255(ionotropic glutamate receptor binding);GO:0097120(receptor localization to synapse);GO:0044224(juxtaparanode region of axon);GO:0043113(receptor clustering);GO:0019233(sensory perception of pain)","04390(Hippo signaling pathway);04530(Tight junction);05165(Human papillomavirus infection)","NA","NA","discs large MAGUK scaffold protein 2 [Source:HGNC Symbol;Acc:HGNC:2901]",0,0,1,0,1,1,"no","no"]
[21078,0,"chr10","-",72059035,72089032,"ENST00000317376",12,5328,"MSTRG.1761","SPOCK2","GO:0005509(calcium ion binding);GO:0007165(signal transduction);GO:0005576(extracellular region);GO:0005578(proteinaceous extracellular matrix);GO:0045595(regulation of cell differentiation);GO:0007416(synapse assembly);GO:0030198(extracellular matrix organization);GO:0005539(glycosaminoglycan binding);GO:0008191(metalloendopeptidase inhibitor activity);GO:0050840(extracellular matrix binding);GO:0010811(positive regulation of cell-substrate adhesion);GO:0010951(negative regulation of endopeptidase activity);GO:0019800(peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan);GO:1990830(cellular response to leukemia inhibitory factor);GO:2000147(positive regulation of cell motility)","NA","NA","NA","SPARC/osteonectin, cwcv and kazal like domains proteoglycan 2 [Source:HGNC Symbol;Acc:HGNC:13564]",{"v":44.395668,"d":"44.40"},0,"inf","inf",1,1,"up","no"]
[113401,0,"chr2","+",110279606,110285681,"ENST00000633535",3,357,"MSTRG.9037","AC140479.6","NA","NA","NA","NA","NA",{"v":0.13968,"d":"0.14"},0,"inf","inf",1,1,"up","no"]
[10478,0,"chr1","-",149928651,149936869,"ENST00000482025",15,2834,"MSTRG.905","MTMR11","GO:0070062(extracellular exosome)","NA","NA","NA","myotubularin related protein 11 [Source:HGNC Symbol;Acc:HGNC:24307]",{"v":0.378775,"d":"0.38"},0,"inf","inf",1,1,"up","no"]
[65522,0,"chr15","+",80075161,80138392,"ENST00000616533",7,1653,"MSTRG.5351","ZFAND6","GO:0006810(transport);GO:0005737(cytoplasm);GO:0015031(protein transport);GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0006915(apoptotic process);GO:0003674(molecular_function);GO:0005575(cellular_component);GO:0071356(cellular response to tumor necrosis factor);GO:0043066(negative regulation of apoptotic process);GO:0006625(protein targeting to peroxisome);GO:0043122(regulation of I-kappaB kinase/NF-kappaB signaling);GO:0031593(polyubiquitin binding)","NA","NA","NA","zinc finger AN1-type containing 6 [Source:HGNC Symbol;Acc:HGNC:30164]",0,0,1,0,1,1,"no","no"]
[74356,0,"chr16","+",67192207,67196008,"ENST00000568839",6,944,"MSTRG.6004","E2F4","GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0046983(protein dimerization activity);GO:0006355(regulation of transcription, DNA-templated);GO:0006366(transcription from RNA polymerase II promoter);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0005515(protein binding);GO:0007049(cell cycle);GO:0005667(transcription factor complex);GO:0000278(mitotic cell cycle);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:0006977(DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0030030(cell projection organization);GO:0044458(motile cilium assembly);GO:0098534(centriole assembly);GO:1903251(multi-ciliated epithelial cell differentiation);GO:0019904(protein domain specific binding);GO:0008134(transcription factor binding);GO:0000790(nuclear chromatin);GO:0001077(transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:1990841(promoter-specific chromatin binding);GO:0001228(transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding);GO:0000083(regulation of transcription involved in G1/S transition of mitotic cell cycle);GO:0002064(epithelial cell development);GO:0006884(cell volume homeostasis);GO:0008015(blood circulation);GO:0008361(regulation of cell size);GO:0009887(animal organ morphogenesis);GO:0042127(regulation of cell proliferation);GO:0060271(cilium assembly)","04350(TGF-beta signaling pathway);04110(Cell cycle);04218(Cellular senescence)","NA","NA","E2F transcription factor 4 [Source:HGNC Symbol;Acc:HGNC:3118]",{"v":0.095458,"d":"0.10"},0,"inf","inf",1,1,"up","no"]
[15159,0,"chr1","-",204528845,204529692,"ENST00000432698",1,848,"ENSG00000236779","AL512306.1","NA","NA","NA","NA","NA",{"v":0.062227,"d":"0.06"},0,"inf","inf",1,1,"up","no"]
[171574,0,"chr7","+",5602872,5606654,"ENST00000473330",4,2215,"ENSG00000075618","FSCN1","GO:0003723(RNA binding);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0007015(actin filament organization);GO:0051015(actin filament binding);GO:0003779(actin binding);GO:0030036(actin cytoskeleton organization);GO:0005856(cytoskeleton);GO:0042995(cell projection);GO:0005515(protein binding);GO:0030054(cell junction);GO:0016477(cell migration);GO:0030674(protein binding, bridging);GO:0045296(cadherin binding);GO:0030027(lamellipodium);GO:0030175(filopodium);GO:0030426(growth cone);GO:0070062(extracellular exosome);GO:0032956(regulation of actin cytoskeleton organization);GO:0002102(podosome);GO:0001725(stress fiber);GO:0071437(invadopodium);GO:0009653(anatomical structure morphogenesis);GO:0005902(microvillus);GO:0031941(filamentous actin);GO:0001726(ruffle);GO:0051017(actin filament bundle assembly);GO:0015629(actin cytoskeleton);GO:0008144(drug binding);GO:0051491(positive regulation of filopodium assembly);GO:0008283(cell proliferation);GO:0007043(cell-cell junction assembly);GO:0005911(cell-cell junction);GO:0032534(regulation of microvillus assembly);GO:0010592(positive regulation of lamellipodium assembly);GO:0030035(microspike assembly);GO:0048870(cell motility);GO:0090091(positive regulation of extracellular matrix disassembly);GO:0071803(positive regulation of podosome assembly);GO:0031253(cell projection membrane);GO:0035089(establishment of apical/basal cell polarity);GO:0043209(myelin sheath);GO:0044393(microspike)","05206(MicroRNAs in cancer)","NA","NA","fascin actin-bundling protein 1 [Source:HGNC Symbol;Acc:HGNC:11148]",{"v":0.066871,"d":"0.07"},{"v":0.03259,"d":"0.03"},{"v":2.05188708192697,"d":"2.05"},{"v":1.03695133970404,"d":"1.04"},1,1,"up","no"]
[121750,0,"chr20","+",4148831,4181976,"ENST00000484515",5,900,"MSTRG.9581","SMOX","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0043231(intracellular membrane-bounded organelle);GO:0005654(nucleoplasm);GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0031965(nuclear membrane);GO:0005829(cytosol);GO:0006596(polyamine biosynthetic process);GO:0046592(polyamine oxidase activity);GO:0052901(spermine:oxygen oxidoreductase (spermidine-forming) activity);GO:0046208(spermine catabolic process);GO:0052894(norspermine:oxygen oxidoreductase activity);GO:0052895(N1-acetylspermine:oxygen oxidoreductase (N1-acetylspermidine-forming) activity);GO:0006598(polyamine catabolic process)","00330(Arginine and proline metabolism);00410(beta-Alanine metabolism)","NA","NA","spermine oxidase [Source:HGNC Symbol;Acc:HGNC:15862]",0,{"v":0.042501,"d":"0.04"},"-inf","-inf",1,1,"down","no"]
[136762,0,"chr3","-",50559599,50567625,"ENST00000484982",5,565,"ENSG00000088543","C3orf18","GO:0016020(membrane);GO:0016021(integral component of membrane)","NA","NA","NA","chromosome 3 open reading frame 18 [Source:HGNC Symbol;Acc:HGNC:24837]",0,{"v":0.106826,"d":"0.11"},"-inf","-inf",1,1,"down","no"]
[16708,0,"chr1","-",228107785,228108573,"ENST00000497758",4,470,"ENSG00000162910","MRPL55","GO:0006412(translation);GO:0030529(intracellular ribonucleoprotein complex);GO:0003735(structural constituent of ribosome);GO:0005840(ribosome);GO:0005739(mitochondrion);GO:0005762(mitochondrial large ribosomal subunit);GO:0005743(mitochondrial inner membrane);GO:0070125(mitochondrial translational elongation);GO:0070126(mitochondrial translational termination)","NA","NA","NA","mitochondrial ribosomal protein L55 [Source:HGNC Symbol;Acc:HGNC:16686]",0,{"v":0.006191,"d":"0.01"},"-inf","-inf",1,1,"down","no"]
[172549,0,"chr7","+",26538378,26541048,"ENST00000623092",1,2671,"ENSG00000280255","AC004947.2","NA","NA","NA","NA","NA",0,0,1,0,1,1,"no","no"]
[137023,0,"chr3","+",52388883,52392556,"ENST00000480649",5,579,"MSTRG.10980","DNAH1","GO:0005737(cytoplasm);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0003777(microtubule motor activity);GO:0005856(cytoskeleton);GO:0042995(cell projection);GO:0005874(microtubule);GO:0003774(motor activity);GO:0007018(microtubule-based movement);GO:0016887(ATPase activity);GO:0030286(dynein complex);GO:0003341(cilium movement);GO:0003351(epithelial cilium movement);GO:0030317(flagellated sperm motility);GO:0060294(cilium movement involved in cell motility);GO:0005858(axonemal dynein complex);GO:0036126(sperm flagellum);GO:0005929(cilium);GO:0051959(dynein light intermediate chain binding);GO:0045503(dynein light chain binding);GO:0045505(dynein intermediate chain binding);GO:0060285(cilium-dependent cell motility);GO:0008569(ATP-dependent microtubule motor activity, minus-end-directed);GO:0036159(inner dynein arm assembly);GO:0036156(inner dynein arm)","05016(Huntington's disease)","NA","NA","dynein axonemal heavy chain 1 [Source:HGNC Symbol;Acc:HGNC:2940]",{"v":0.162042,"d":"0.16"},0,"inf","inf",1,1,"up","no"]
[188238,0,"chr8","+",144084793,144086183,"ENST00000530796",4,936,"MSTRG.14626","GPAA1","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0042765(GPI-anchor transamidase complex);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0006506(GPI anchor biosynthetic process);GO:0005515(protein binding);GO:0015631(tubulin binding);GO:0006461(protein complex assembly);GO:0003923(GPI-anchor transamidase activity);GO:0034235(GPI anchor binding);GO:0006621(protein retention in ER lumen);GO:0016255(attachment of GPI anchor to protein)","00563(Glycosylphosphatidylinositol(GPI)-anchor biosynthesis)","NA","NA","glycosylphosphatidylinositol anchor attachment 1 [Source:HGNC Symbol;Acc:HGNC:4446]",{"v":0.466095,"d":"0.47"},{"v":0.519285,"d":"0.52"},{"v":0.897570698171524,"d":"0.90"},{"v":-0.155902515969009,"d":"-0.16"},1,1,"down","no"]
[194982,0,"chr9","+",136993381,136993977,"ENST00000463765",2,496,"MSTRG.15113","PAXX","GO:0005634(nucleus);GO:0042803(protein homodimerization activity);GO:0006303(double-strand break repair via nonhomologous end joining);GO:0006281(DNA repair);GO:0006974(cellular response to DNA damage stimulus);GO:0005515(protein binding);GO:0070062(extracellular exosome);GO:0035861(site of double-strand break);GO:0032947(protein complex scaffold);GO:0051103(DNA ligation involved in DNA repair);GO:0043564(Ku70:Ku80 complex);GO:0070419(nonhomologous end joining complex)","NA","NA","NA","PAXX, non-homologous end joining factor [Source:HGNC Symbol;Acc:HGNC:27849]",{"v":0.295601,"d":"0.30"},{"v":0.140566,"d":"0.14"},{"v":2.10293385313661,"d":"2.10"},{"v":1.07240347144267,"d":"1.07"},1,1,"up","no"]
[106383,0,"chr19","-",57803841,57813404,"ENST00000594473",2,335,"MSTRG.8462","ZNF552","GO:0003676(nucleic acid binding);GO:0006355(regulation of transcription, DNA-templated);GO:0005622(intracellular);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0045892(negative regulation of transcription, DNA-templated)","NA","NA","NA","zinc finger protein 552 [Source:HGNC Symbol;Acc:HGNC:26135]",{"v":0.698238,"d":"0.70"},{"v":0.814383,"d":"0.81"},{"v":0.857382828472598,"d":"0.86"},{"v":-0.221988571510763,"d":"-0.22"},1,1,"down","no"]
[74326,0,"chr16","+",67171634,67173003,"ENST00000568199",2,613,"MSTRG.6012","NOL3","GO:0042981(regulation of apoptotic process);GO:0006397(mRNA processing);GO:0008380(RNA splicing);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0046872(metal ion binding);GO:0005739(mitochondrion);GO:0005515(protein binding);GO:0006915(apoptotic process);GO:0005730(nucleolus);GO:0005509(calcium ion binding);GO:0042802(identical protein binding);GO:0016529(sarcoplasmic reticulum);GO:0043066(negative regulation of apoptotic process);GO:0051259(protein oligomerization);GO:0003723(RNA binding);GO:0005829(cytosol);GO:0089720(caspase binding);GO:2001237(negative regulation of extrinsic apoptotic signaling pathway);GO:0043027(cysteine-type endopeptidase inhibitor activity involved in apoptotic process);GO:0090201(negative regulation of release of cytochrome c from mitochondria);GO:0005102(receptor binding);GO:0005123(death receptor binding);GO:0035877(death effector domain binding);GO:0001666(response to hypoxia);GO:0001974(blood vessel remodeling);GO:0002931(response to ischemia);GO:0006376(mRNA splice site selection);GO:0010468(regulation of gene expression);GO:0010659(cardiac muscle cell apoptotic process);GO:0010664(negative regulation of striated muscle cell apoptotic process);GO:0010667(negative regulation of cardiac muscle cell apoptotic process);GO:0010804(negative regulation of tumor necrosis factor-mediated signaling pathway);GO:0014736(negative regulation of muscle atrophy);GO:0014808(release of sequestered calcium ion into cytosol by sarcoplasmic reticulum);GO:0014876(response to injury involved in regulation of muscle adaptation);GO:0042345(regulation of NF-kappaB import into nucleus);GO:0060547(negative regulation of necrotic cell death);GO:0097193(intrinsic apoptotic signaling pathway);GO:1902109(negative regulation of mitochondrial membrane permeability involved in apoptotic process);GO:1902176(negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway);GO:1990001(inhibition of cysteine-type endopeptidase activity involved in apoptotic process);GO:0016528(sarcoplasm)","NA","NA","NA","nucleolar protein 3 [Source:HGNC Symbol;Acc:HGNC:7869]",0,0,1,0,1,1,"no","no"]
[164009,0,"chr6","-",30291006,30326376,"ENST00000454129",3,4433,"MSTRG.12766","HCG18","NA","NA","NA","NA","HLA complex group 18 (non-protein coding) [Source:HGNC Symbol;Acc:HGNC:31337]",{"v":0.01279,"d":"0.01"},{"v":0.194445,"d":"0.19"},{"v":0.0657769549229859,"d":"0.07"},{"v":-3.92627396815041,"d":"-3.93"},1,1,"down","no"]
[50663,0,"chr13","-",52844459,52845693,"ENST00000613548",2,744,"ENSG00000136099","PCDH8","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005509(calcium ion binding);GO:0007155(cell adhesion);GO:0007156(homophilic cell adhesion via plasma membrane adhesion molecules);GO:0005886(plasma membrane);GO:0042995(cell projection);GO:0030054(cell junction);GO:0045202(synapse);GO:0045211(postsynaptic membrane);GO:0030425(dendrite);GO:0007399(nervous system development);GO:0005887(integral component of plasma membrane);GO:0007267(cell-cell signaling);GO:0042734(presynaptic membrane);GO:0001756(somitogenesis);GO:0007268(chemical synaptic transmission);GO:0016331(morphogenesis of embryonic epithelium)","NA","NA","NA","protocadherin 8 [Source:HGNC Symbol;Acc:HGNC:8660]",{"v":0.060927,"d":"0.06"},0,"inf","inf",1,1,"up","no"]
[73612,0,"chr16","+",57628624,57651367,"ENST00000563374",4,568,"MSTRG.5971","ADGRG1","GO:0005622(intracellular);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0004930(G-protein coupled receptor activity);GO:0007186(G-protein coupled receptor signaling pathway);GO:0007155(cell adhesion);GO:0005886(plasma membrane);GO:0004871(signal transducer activity);GO:0007165(signal transduction);GO:0005576(extracellular region);GO:0004888(transmembrane signaling receptor activity);GO:0007166(cell surface receptor signaling pathway);GO:0007275(multicellular organism development);GO:0007399(nervous system development);GO:0030154(cell differentiation);GO:0045121(membrane raft);GO:0008201(heparin binding);GO:0070062(extracellular exosome);GO:0050840(extracellular matrix binding);GO:0008285(negative regulation of cell proliferation);GO:0005887(integral component of plasma membrane);GO:0007267(cell-cell signaling);GO:0045785(positive regulation of cell adhesion);GO:0016477(cell migration);GO:0001525(angiogenesis);GO:0007266(Rho protein signal transduction);GO:0005518(collagen binding);GO:0070528(protein kinase C signaling);GO:0035025(positive regulation of Rho protein signal transduction);GO:2001223(negative regulation of neuron migration);GO:0021819(layer formation in cerebral cortex);GO:0021801(cerebral cortex radial glia guided migration);GO:0007420(brain development);GO:0010573(vascular endothelial growth factor production);GO:0097451(glial limiting end-foot);GO:0021796(cerebral cortex regionalization);GO:0072520(seminiferous tubule development);GO:2000179(positive regulation of neural precursor cell proliferation)","NA","NA","NA","adhesion G protein-coupled receptor G1 [Source:HGNC Symbol;Acc:HGNC:4512]",{"v":0.017314,"d":"0.02"},{"v":8.6e-05,"d":"0.00"},{"v":201.325581395349,"d":"201.33"},{"v":7.65338668944269,"d":"7.65"},1,1,"up","no"]
[162577,0,"chr6","+",4776442,4954510,"ENST00000472453",6,1764,"MSTRG.12642","CDYL","GO:0005634(nucleus);GO:0016607(nuclear speck);GO:0005654(nucleoplasm);GO:0016740(transferase activity);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003824(catalytic activity);GO:0016746(transferase activity, transferring acyl groups);GO:0008152(metabolic process);GO:0005515(protein binding);GO:0016604(nuclear body);GO:0004402(histone acetyltransferase activity);GO:0016573(histone acetylation);GO:1903507(negative regulation of nucleic acid-templated transcription);GO:0003714(transcription corepressor activity);GO:0030674(protein binding, bridging);GO:0007283(spermatogenesis);GO:0035064(methylated histone binding);GO:0016020(membrane);GO:0016021(integral component of membrane)","NA","NA","NA","chromodomain Y like [Source:HGNC Symbol;Acc:HGNC:1811]",0,0,1,0,1,1,"no","no"]
[47005,0,"chr12","-",113298781,113308843,"ENST00000550047",4,2493,"MSTRG.3761","SLC8B1","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0055085(transmembrane transport);GO:0005743(mitochondrial inner membrane);GO:0005739(mitochondrion);GO:0006811(ion transport);GO:0015297(antiporter activity);GO:0006814(sodium ion transport);GO:0006816(calcium ion transport);GO:0050896(response to stimulus);GO:0005886(plasma membrane);GO:0042803(protein homodimerization activity);GO:0086036(regulation of cardiac muscle cell membrane potential);GO:0050796(regulation of insulin secretion);GO:0042593(glucose homeostasis);GO:0006851(mitochondrial calcium ion transmembrane transport);GO:0051560(mitochondrial calcium ion homeostasis);GO:0099093(mitochondrial calcium release);GO:0051480(regulation of cytosolic calcium ion concentration);GO:0005432(calcium:sodium antiporter activity);GO:2001256(regulation of store-operated calcium entry);GO:0032592(integral component of mitochondrial membrane);GO:0015368(calcium:cation antiporter activity);GO:0042802(identical protein binding);GO:0086038(calcium:sodium antiporter activity involved in regulation of cardiac muscle cell membrane potential);GO:0035725(sodium ion transmembrane transport);GO:0070588(calcium ion transmembrane transport);GO:1901623(regulation of lymphocyte chemotaxis);GO:0030061(mitochondrial crista);GO:0042383(sarcolemma)","NA","NA","NA","solute carrier family 8 member B1 [Source:HGNC Symbol;Acc:HGNC:26175]",{"v":0.043759,"d":"0.04"},{"v":0.02839,"d":"0.03"},{"v":1.54135258893977,"d":"1.54"},{"v":0.624196920340438,"d":"0.62"},1,1,"up","no"]
[128840,0,"chr22","+",20703716,20704558,"ENST00000428752",3,614,"ENSG00000226287","TMEM191A","NA","NA","NA","NA","transmembrane protein 191A (pseudogene) [Source:HGNC Symbol;Acc:HGNC:25317]",{"v":0.018971,"d":"0.02"},0,"inf","inf",1,1,"up","no"]
[134847,0,"chr3","+",38496272,38525951,"ENST00000287675",6,2792,"ENSG00000157036","EXOG","GO:0003676(nucleic acid binding);GO:0016020(membrane);GO:0046872(metal ion binding);GO:0016787(hydrolase activity);GO:0005743(mitochondrial inner membrane);GO:0005739(mitochondrion);GO:0090305(nucleic acid phosphodiester bond hydrolysis);GO:0004519(endonuclease activity);GO:0004518(nuclease activity);GO:0008150(biological_process);GO:0005575(cellular_component);GO:0043234(protein complex);GO:0008409(5'-3' exonuclease activity);GO:0016021(integral component of membrane)","NA","NA","NA","exo/endonuclease G [Source:HGNC Symbol;Acc:HGNC:3347]",0,{"v":0.027452,"d":"0.03"},"-inf","-inf",1,1,"down","no"]
[127379,0,"chr21","+",41450928,41452820,"ENST00000491110",2,516,"MSTRG.10064","MX1","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005525(GTP binding);GO:0000166(nucleotide binding);GO:0005829(cytosol);GO:0031965(nuclear membrane);GO:0003924(GTPase activity);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005515(protein binding);GO:0048471(perinuclear region of cytoplasm);GO:0002376(immune system process);GO:0045087(innate immune response);GO:0042802(identical protein binding);GO:0051607(defense response to virus);GO:0008017(microtubule binding);GO:0009615(response to virus);GO:0045071(negative regulation of viral genome replication);GO:0007165(signal transduction);GO:0006915(apoptotic process);GO:0006952(defense response);GO:0060337(type I interferon signaling pathway);GO:0003374(dynamin family protein polymerization involved in mitochondrial fission);GO:0061025(membrane fusion);GO:0031966(mitochondrial membrane);GO:0034340(response to type I interferon);GO:0000266(mitochondrial fission)","05162(Measles);05164(Influenza A);05165(Human papillomavirus infection)","NA","NA","MX dynamin like GTPase 1 [Source:HGNC Symbol;Acc:HGNC:7532]",{"v":0.150122,"d":"0.15"},{"v":0.114971,"d":"0.11"},{"v":1.30573796870515,"d":"1.31"},{"v":0.38486541053048,"d":"0.38"},1,1,"up","no"]
[156478,0,"chr5","-",87404842,87412889,"ENST00000513499",5,606,"ENSG00000134480","CCNH","GO:0006351(transcription, DNA-templated);GO:0045859(regulation of protein kinase activity);GO:0016538(cyclin-dependent protein serine/threonine kinase regulator activity);GO:0070985(TFIIK complex);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0006355(regulation of transcription, DNA-templated);GO:0006468(protein phosphorylation);GO:0005515(protein binding);GO:0007049(cell cycle);GO:0016310(phosphorylation);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0006366(transcription from RNA polymerase II promoter);GO:0000086(G2/M transition of mitotic cell cycle);GO:0006368(transcription elongation from RNA polymerase II promoter);GO:0006370(7-methylguanosine mRNA capping);GO:0006367(transcription initiation from RNA polymerase II promoter);GO:0000082(G1/S transition of mitotic cell cycle);GO:0006361(transcription initiation from RNA polymerase I promoter);GO:0006362(transcription elongation from RNA polymerase I promoter);GO:0006363(termination of RNA polymerase I transcription);GO:0008094(DNA-dependent ATPase activity);GO:0006283(transcription-coupled nucleotide-excision repair);GO:0045737(positive regulation of cyclin-dependent protein serine/threonine kinase activity);GO:1901409(positive regulation of phosphorylation of RNA polymerase II C-terminal domain);GO:0050821(protein stabilization);GO:0008353(RNA polymerase II carboxy-terminal domain kinase activity);GO:0006294(nucleotide-excision repair, preincision complex assembly);GO:0019907(cyclin-dependent protein kinase activating kinase holoenzyme complex);GO:0005675(holo TFIIH complex);GO:0016301(kinase activity)","03022(Basal transcription factors);03420(Nucleotide excision repair);04110(Cell cycle)","NA","NA","cyclin H [Source:HGNC Symbol;Acc:HGNC:1594]",{"v":0.02872,"d":"0.03"},0,"inf","inf",1,1,"up","no"]
[119613,0,"chr2","-",221420445,221425540,"ENST00000472696",3,531,"ENSG00000116106","EPHA4","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0004713(protein tyrosine kinase activity);GO:0005003(ephrin receptor activity);GO:0007169(transmembrane receptor protein tyrosine kinase signaling pathway);GO:0018108(peptidyl-tyrosine phosphorylation);GO:0005887(integral component of plasma membrane);GO:0048013(ephrin receptor signaling pathway);GO:0005737(cytoplasm);GO:0007155(cell adhesion);GO:0005886(plasma membrane);GO:0042995(cell projection);GO:0004714(transmembrane receptor protein tyrosine kinase activity);GO:0007275(multicellular organism development);GO:0030054(cell junction);GO:0045202(synapse);GO:0045211(postsynaptic membrane);GO:0007399(nervous system development);GO:0030425(dendrite);GO:0005515(protein binding);GO:0005768(endosome);GO:0030424(axon);GO:0005769(early endosome);GO:0014069(postsynaptic density);GO:0031901(early endosome membrane);GO:1904646(cellular response to amyloid-beta);GO:0046777(protein autophosphorylation);GO:0043087(regulation of GTPase activity);GO:0050770(regulation of axonogenesis);GO:0061001(regulation of dendritic spine morphogenesis);GO:0048681(negative regulation of axon regeneration);GO:0008045(motor neuron axon guidance);GO:1900272(negative regulation of long-term synaptic potentiation);GO:1905244(regulation of modification of synaptic structure);GO:0010977(negative regulation of neuron projection development);GO:0061098(positive regulation of protein tyrosine kinase activity);GO:1902961(positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process);GO:0050821(protein stabilization);GO:1902004(positive regulation of amyloid-beta formation);GO:1903051(negative regulation of proteolysis involved in cellular protein catabolic process);GO:0005005(transmembrane-ephrin receptor activity);GO:0005004(GPI-linked ephrin receptor activity);GO:0097155(fasciculation of sensory neuron axon);GO:0097156(fasciculation of motor neuron axon);GO:1990782(protein tyrosine kinase binding);GO:0043197(dendritic spine);GO:0042731(PH domain binding);GO:0097161(DH domain binding);GO:0021957(corticospinal tract morphogenesis);GO:0048710(regulation of astrocyte differentiation);GO:0097485(neuron projection guidance);GO:2001108(positive regulation of Rho guanyl-nucleotide exchange factor activity);GO:0043198(dendritic shaft);GO:0042802(identical protein binding);GO:0046875(ephrin receptor binding);GO:0007411(axon guidance);GO:0007628(adult walking behavior);GO:0008347(glial cell migration);GO:0043507(positive regulation of JUN kinase activity);GO:0050775(positive regulation of dendrite morphogenesis);GO:0072178(nephric duct morphogenesis);GO:0106030(-);GO:0005741(mitochondrial outer membrane);GO:0005783(endoplasmic reticulum);GO:0005794(Golgi apparatus);GO:0009986(cell surface);GO:0030175(filopodium);GO:0031594(neuromuscular junction);GO:0043204(perikaryon);GO:0043679(axon terminus);GO:0044295(axonal growth cone);GO:0044297(cell body)","04360(Axon guidance)","NA","NA","EPH receptor A4 [Source:HGNC Symbol;Acc:HGNC:3388]",{"v":0.000221,"d":"0.00"},{"v":0.048577,"d":"0.05"},{"v":0.00454947814809478,"d":"0.00"},{"v":-7.78008321546803,"d":"-7.78"},1,1,"down","no"]
[32350,0,"chr11","+",69371463,69372512,"ENST00000561588",2,372,"ENSG00000260877","AP005233.2","NA","NA","NA","NA","NA",{"v":3.31E-3,"d":"0.00"},{"v":0.273612,"d":"0.27"},{"v":0.0120974226276625,"d":"0.01"},{"v":-6.36915647767673,"d":"-6.37"},1,1,"down","no"]
[174812,0,"chr7","-",73048481,73057911,"ENST00000340073",8,2281,"MSTRG.13692","SPDYE11","NA","NA","NA","NA","speedy/RINGO cell cycle regulator family member E11 [Source:HGNC Symbol;Acc:HGNC:51507]",{"v":0.000401,"d":"0.00"},0,"inf","inf",1,1,"up","no"]
[39600,0,"chr12","-",22470836,22472445,"ENST00000540245",4,425,"MSTRG.3254","C2CD5","GO:0006810(transport);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0015031(protein transport);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0042995(cell projection);GO:0005815(microtubule organizing center);GO:0030659(cytoplasmic vesicle membrane);GO:0031410(cytoplasmic vesicle);GO:0005544(calcium-dependent phospholipid binding);GO:0005509(calcium ion binding);GO:0008289(lipid binding);GO:0005938(cell cortex);GO:0032587(ruffle membrane);GO:0090314(positive regulation of protein targeting to membrane);GO:0001726(ruffle);GO:0032869(cellular response to insulin stimulus);GO:0010828(positive regulation of glucose transport);GO:0031340(positive regulation of vesicle fusion);GO:0038028(insulin receptor signaling pathway via phosphatidylinositol 3-kinase);GO:0065002(intracellular protein transmembrane transport);GO:0006906(vesicle fusion);GO:0072659(protein localization to plasma membrane);GO:2001275(positive regulation of glucose import in response to insulin stimulus)","NA","NA","NA","C2 calcium dependent domain containing 5 [Source:HGNC Symbol;Acc:HGNC:29062]",{"v":0.034692,"d":"0.03"},{"v":0.13785,"d":"0.14"},{"v":0.251664853101197,"d":"0.25"},{"v":-1.99042434758671,"d":"-1.99"},1,1,"down","no"]
[77462,0,"chr17","-",1480527,1491669,"ENST00000570984",7,901,"ENSG00000197879","MYO1C","GO:0006810(transport);GO:0051028(mRNA transport);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0015031(protein transport);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0003774(motor activity);GO:0016459(myosin complex);GO:0003779(actin binding);GO:0005886(plasma membrane);GO:0042995(cell projection);GO:0016604(nuclear body);GO:0031410(cytoplasmic vesicle);GO:0045121(membrane raft);GO:0005643(nuclear pore);GO:0005654(nucleoplasm);GO:0005730(nucleolus);GO:0038096(Fc-gamma receptor signaling pathway involved in phagocytosis);GO:0005516(calmodulin binding);GO:0005515(protein binding);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0031941(filamentous actin);GO:0030335(positive regulation of cell migration);GO:0090314(positive regulation of protein targeting to membrane);GO:0005902(microvillus);GO:0005102(receptor binding);GO:0016461(unconventional myosin complex);GO:0000146(microfilament motor activity);GO:0008022(protein C-terminus binding);GO:0017160(Ral GTPase binding);GO:0030898(actin-dependent ATPase activity);GO:0051015(actin filament binding);GO:0006605(protein targeting);GO:0006612(protein targeting to membrane);GO:0030838(positive regulation of actin filament polymerization);GO:0038089(positive regulation of cell migration by vascular endothelial growth factor signaling pathway);GO:0045815(positive regulation of gene expression, epigenetic);GO:1900078(positive regulation of cellular response to insulin stimulus);GO:1900748(positive regulation of vascular endothelial growth factor signaling pathway);GO:2000810(regulation of bicellular tight junction assembly);GO:0001726(ruffle);GO:0005903(brush border);GO:0009925(basal plasma membrane);GO:0016328(lateral plasma membrane);GO:0032420(stereocilium);GO:0032421(stereocilium bundle);GO:0032587(ruffle membrane);GO:0045160(myosin I complex);GO:0060171(stereocilium membrane)","NA","NA","NA","myosin IC [Source:HGNC Symbol;Acc:HGNC:7597]",{"v":0.111373,"d":"0.11"},{"v":0.606657,"d":"0.61"},{"v":0.18358479338407,"d":"0.18"},{"v":-2.4454815318762,"d":"-2.45"},1,1,"down","no"]
[131229,0,"chr22","+",38200767,38204050,"ENST00000624676",1,3284,"MSTRG.10449","MAFF","GO:0005634(nucleus);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0005739(mitochondrion);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0005654(nucleoplasm);GO:0001228(transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding);GO:0043565(sequence-specific DNA binding);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0006366(transcription from RNA polymerase II promoter);GO:0007596(blood coagulation);GO:0007567(parturition);GO:0001701(in utero embryonic development);GO:0035914(skeletal muscle cell differentiation);GO:0045604(regulation of epidermal cell differentiation)","NA","NA","NA","MAF bZIP transcription factor F [Source:HGNC Symbol;Acc:HGNC:6780]",{"v":0.08338,"d":"0.08"},0,"inf","inf",1,1,"up","no"]
[110154,0,"chr2","+",62705652,62864904,"ENST00000405482",9,1311,"ENSG00000115504","EHBP1","GO:0006810(transport);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0015031(protein transport);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0005768(endosome);GO:0006897(endocytosis)","NA","NA","NA","EH domain binding protein 1 [Source:HGNC Symbol;Acc:HGNC:29144]",{"v":0.028603,"d":"0.03"},0,"inf","inf",1,1,"up","no"]
[74734,0,"chr16","-",67992557,67994328,"ENST00000574865",3,559,"MSTRG.6048","DPEP2","GO:0016020(membrane);GO:0046872(metal ion binding);GO:0016787(hydrolase activity);GO:0008233(peptidase activity);GO:0006508(proteolysis);GO:0008237(metallopeptidase activity);GO:0008235(metalloexopeptidase activity);GO:0008239(dipeptidyl-peptidase activity);GO:0016805(dipeptidase activity);GO:0031225(anchored component of membrane);GO:0008238(exopeptidase activity)","NA","NA","NA","dipeptidase 2 [Source:HGNC Symbol;Acc:HGNC:23028]",{"v":0.801097,"d":"0.80"},{"v":0.791087,"d":"0.79"},{"v":1.0126534755343,"d":"1.01"},{"v":0.0181405762565583,"d":"0.02"},1,1,"up","no"]
[96604,0,"chr19","-",10927598,10928547,"ENST00000592505",2,530,"MSTRG.7815","YIPF2","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005515(protein binding);GO:0017137(Rab GTPase binding);GO:0005794(Golgi apparatus);GO:0030133(transport vesicle)","NA","NA","NA","Yip1 domain family member 2 [Source:HGNC Symbol;Acc:HGNC:28476]",{"v":0.124099,"d":"0.12"},{"v":0.133237,"d":"0.13"},{"v":0.931415447660935,"d":"0.93"},{"v":-0.102503285223202,"d":"-0.10"},1,1,"down","no"]
[99832,0,"chr19","-",34593329,34632976,"ENST00000595326",4,643,"ENSG00000205209","SCGB2B2","GO:0005576(extracellular region)","NA","NA","NA","secretoglobin family 2B member 2 [Source:HGNC Symbol;Acc:HGNC:27616]",{"v":0.018328,"d":"0.02"},0,"inf","inf",1,1,"up","no"]
[180515,0,"chr7","+",155746586,155781485,"ENST00000341148",5,7058,"MSTRG.14155","RBM33","GO:0003676(nucleic acid binding);GO:0003723(RNA binding)","NA","NA","NA","RNA binding motif protein 33 [Source:HGNC Symbol;Acc:HGNC:27223]",{"v":3e-05,"d":"0.00"},0,"inf","inf",1,1,"up","no"]
[57646,0,"chr14","+",90396502,90404496,"ENST00000557020",5,557,"MSTRG.4607","CALM1","GO:0005509(calcium ion binding);GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0000922(spindle pole);GO:0005819(spindle);GO:0044325(ion channel binding);GO:0090150(establishment of protein localization to membrane);GO:0090151(establishment of protein localization to mitochondrial membrane);GO:1900242(regulation of synaptic vesicle endocytosis);GO:2000300(regulation of synaptic vesicle exocytosis);GO:0014069(postsynaptic density);GO:0030672(synaptic vesicle membrane);GO:0031966(mitochondrial membrane);GO:0043209(myelin sheath);GO:0019855(calcium channel inhibitor activity);GO:0060315(negative regulation of ryanodine-sensitive calcium-release channel activity)","04014(Ras signaling pathway);04015(Rap1 signaling pathway);04371(Apelin signaling pathway);04020(Calcium signaling pathway);04070(Phosphatidylinositol signaling system);04024(cAMP signaling pathway);04022(cGMP - PKG signaling pathway);04114(Oocyte meiosis);04218(Cellular senescence);04910(Insulin signaling pathway);04922(Glucagon signaling pathway);04912(GnRH signaling pathway);04915(Estrogen signaling pathway);04921(Oxytocin signaling pathway);04916(Melanogenesis);04924(Renin secretion);04925(Aldosterone synthesis and secretion);04261(Adrenergic signaling in cardiomyocytes);04270(Vascular smooth muscle contraction);04970(Salivary secretion);04971(Gastric acid secretion);04728(Dopaminergic synapse);04720(Long-term potentiation);04722(Neurotrophin signaling pathway);04744(Phototransduction);04740(Olfactory transduction);04750(Inflammatory mediator regulation of TRP channels);04713(Circadian entrainment);05200(Pathways in cancer);05214(Glioma);05010(Alzheimer's disease);05031(Amphetamine addiction);05034(Alcoholism);05418(Fluid shear stress and atherosclerosis);05133(Pertussis);05152(Tuberculosis);05167(Kaposi's sarcoma-associated herpesvirus infection)","NA","NA","calmodulin 1 [Source:HGNC Symbol;Acc:HGNC:1442]",{"v":0.571414,"d":"0.57"},{"v":0.686417,"d":"0.69"},{"v":0.83245898630133,"d":"0.83"},{"v":-0.264548899841312,"d":"-0.26"},1,1,"down","no"]
[51962,0,"chr13","-",113177613,113178478,"ENST00000462653",2,669,"MSTRG.4113","PCID2","GO:0005515(protein binding);GO:0045893(positive regulation of transcription, DNA-templated);GO:0003690(double-stranded DNA binding);GO:0003723(RNA binding);GO:0005575(cellular_component);GO:0006368(transcription elongation from RNA polymerase II promoter);GO:0005643(nuclear pore);GO:0043066(negative regulation of apoptotic process);GO:0090267(positive regulation of mitotic cell cycle spindle assembly checkpoint);GO:0048536(spleen development);GO:2000117(negative regulation of cysteine-type endopeptidase activity);GO:0043488(regulation of mRNA stability);GO:0000973(posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery);GO:0035327(transcriptionally active chromatin);GO:0016973(poly(A)+ mRNA export from nucleus);GO:0071033(nuclear retention of pre-mRNA at the site of transcription);GO:0070390(transcription export complex 2);GO:0045579(positive regulation of B cell differentiation)","NA","NA","NA","PCI domain containing 2 [Source:HGNC Symbol;Acc:HGNC:25653]",{"v":0.086405,"d":"0.09"},{"v":0.232346,"d":"0.23"},{"v":0.371880729601543,"d":"0.37"},{"v":-1.42708810366936,"d":"-1.43"},1,1,"down","no"]
[117431,0,"chr2","-",191032862,191151013,"ENST00000495849",21,2208,"MSTRG.9309","STAT4","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0007165(signal transduction);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0004871(signal transducer activity);GO:0005515(protein binding);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0019221(cytokine-mediated signaling pathway);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0035722(interleukin-12-mediated signaling pathway);GO:0007259(JAK-STAT cascade)","04630(Jak-STAT signaling pathway);04217(Necroptosis);04658(Th1 and Th2 cell differentiation);05200(Pathways in cancer);05321(Inflammatiory bowel disease (IBD));05161(Hepatitis B)","NA","NA","signal transducer and activator of transcription 4 [Source:HGNC Symbol;Acc:HGNC:11365]",{"v":1.268043,"d":"1.27"},{"v":0.076692,"d":"0.08"},{"v":16.5342278203724,"d":"16.53"},{"v":4.04738376540989,"d":"4.05"},1,1,"up","no"]
[184070,0,"chr8","+",58411359,58434941,"ENST00000522978",7,717,"MSTRG.14367","UBXN2B","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005794(Golgi apparatus);GO:0005829(cytosol);GO:0005783(endoplasmic reticulum);GO:0050790(regulation of catalytic activity);GO:0005515(protein binding);GO:0043161(proteasome-mediated ubiquitin-dependent protein catabolic process);GO:0000045(autophagosome assembly);GO:0007030(Golgi organization);GO:0043130(ubiquitin binding);GO:0061025(membrane fusion);GO:0019888(protein phosphatase regulator activity);GO:0031468(nuclear envelope reassembly)","NA","NA","NA","UBX domain protein 2B [Source:HGNC Symbol;Acc:HGNC:27035]",{"v":0.077417,"d":"0.08"},{"v":0.369052,"d":"0.37"},{"v":0.209772606570348,"d":"0.21"},{"v":-2.25310180088738,"d":"-2.25"},1,1,"down","no"]
[102646,0,"chr19","+",44955558,44974490,"ENST00000585961",4,572,"MSTRG.8218","CLPTM1","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005515(protein binding);GO:0007275(multicellular organism development);GO:0030154(cell differentiation);GO:0005887(integral component of plasma membrane);GO:0009897(external side of plasma membrane);GO:0033081(regulation of T cell differentiation in thymus)","NA","NA","NA","CLPTM1, transmembrane protein [Source:HGNC Symbol;Acc:HGNC:2087]",{"v":1.03E-4,"d":"0.00"},0,"inf","inf",1,1,"up","no"]
[161561,0,"chr5","-",177402163,177403750,"ENST00000504406",3,943,"MSTRG.12576","F12","GO:0005615(extracellular space);GO:0016787(hydrolase activity);GO:0005509(calcium ion binding);GO:0005576(extracellular region);GO:0005515(protein binding);GO:0008233(peptidase activity);GO:0006508(proteolysis);GO:0004252(serine-type endopeptidase activity);GO:0008236(serine-type peptidase activity);GO:0005886(plasma membrane);GO:0070062(extracellular exosome);GO:0045087(innate immune response);GO:0007596(blood coagulation);GO:0007599(hemostasis);GO:0016485(protein processing);GO:0007597(blood coagulation, intrinsic pathway);GO:0030194(positive regulation of blood coagulation);GO:0042730(fibrinolysis);GO:0051919(positive regulation of fibrinolysis);GO:0051787(misfolded protein binding);GO:0002353(plasma kallikrein-kinin cascade);GO:0002542(Factor XII activation);GO:0010756(positive regulation of plasminogen activation);GO:0016540(protein autoprocessing);GO:0030193(regulation of blood coagulation);GO:0031638(zymogen activation);GO:0051788(response to misfolded protein)","04610(Complement and coagulation cascades)","NA","NA","coagulation factor XII [Source:HGNC Symbol;Acc:HGNC:3530]",{"v":0.069206,"d":"0.07"},0,"inf","inf",1,1,"up","no"]
[154240,0,"chr5","+",36667717,36669958,"ENST00000624112",1,2242,"ENSG00000279400","AC008957.3","NA","NA","NA","NA","NA",0,{"v":0.022699,"d":"0.02"},"-inf","-inf",1,1,"down","no"]
[86041,0,"chr17","-",58205740,58219605,"ENST00000537529",18,2083,"ENSG00000011143","MKS1","GO:0005737(cytoplasm);GO:0005856(cytoskeleton);GO:0042995(cell projection);GO:0005813(centrosome);GO:0005815(microtubule organizing center);GO:0005515(protein binding);GO:0060271(cilium assembly);GO:0005929(cilium);GO:0005829(cytosol);GO:0030030(cell projection organization);GO:0036064(ciliary basal body);GO:0097711(ciliary basal body docking);GO:0036038(MKS complex);GO:0001843(neural tube closure);GO:0007368(determination of left/right symmetry);GO:0008589(regulation of smoothened signaling pathway);GO:0010669(epithelial structure maintenance);GO:0042733(embryonic digit morphogenesis);GO:0044458(motile cilium assembly);GO:0048706(embryonic skeletal system development);GO:0048754(branching morphogenesis of an epithelial tube);GO:0060122(inner ear receptor stereocilium organization);GO:0060322(head development);GO:0060828(regulation of canonical Wnt signaling pathway);GO:0061009(common bile duct development);GO:1901620(regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning);GO:1905515(non-motile cilium assembly);GO:1990403(embryonic brain development);GO:2000095(regulation of Wnt signaling pathway, planar cell polarity pathway);GO:0005814(centriole);GO:0016020(membrane);GO:0035869(ciliary transition zone)","NA","NA","NA","Meckel syndrome, type 1 [Source:HGNC Symbol;Acc:HGNC:7121]",0,0,1,0,1,1,"no","no"]
[119782,0,"chr2","+",227164565,227314792,"ENST00000396578",52,8097,"MSTRG.9462","COL4A3","GO:0043231(intracellular membrane-bounded organelle);GO:0005783(endoplasmic reticulum);GO:0007155(cell adhesion);GO:0010951(negative regulation of endopeptidase activity);GO:0005576(extracellular region);GO:0005581(collagen trimer);GO:0005578(proteinaceous extracellular matrix);GO:0005201(extracellular matrix structural constituent);GO:0005604(basement membrane);GO:0005515(protein binding);GO:0008283(cell proliferation);GO:0030574(collagen catabolic process);GO:0005178(integrin binding);GO:0005788(endoplasmic reticulum lumen);GO:0030198(extracellular matrix organization);GO:0005198(structural molecule activity);GO:0016525(negative regulation of angiogenesis);GO:0008285(negative regulation of cell proliferation);GO:0006919(activation of cysteine-type endopeptidase activity involved in apoptotic process);GO:0007605(sensory perception of sound);GO:0032836(glomerular basement membrane development);GO:0008015(blood circulation);GO:0007166(cell surface receptor signaling pathway);GO:0008191(metalloendopeptidase inhibitor activity);GO:0005587(collagen type IV trimer);GO:0038063(collagen-activated tyrosine kinase receptor signaling pathway);GO:0072577(endothelial cell apoptotic process)","04151(PI3K-Akt signaling pathway);04512(ECM-receptor interaction);04510(Focal adhesion);04926(Relaxin signaling pathway);04974(Protein digestion and absorption);05200(Pathways in cancer);05222(Small cell lung cancer);04933(AGE-RAGE signaling pathway in diabetic complications);05165(Human papillomavirus infection);05146(Amoebiasis)","K06237","NA","collagen type IV alpha 3 chain [Source:HGNC Symbol;Acc:HGNC:2204]",{"v":0.074145,"d":"0.07"},{"v":0.084987,"d":"0.08"},{"v":0.872427547742596,"d":"0.87"},{"v":-0.196892769699893,"d":"-0.20"},1,1,"down","no"]
[69853,0,"chr16","-",14608107,14610699,"ENST00000563155",3,335,"MSTRG.5680","PARN","GO:0005634(nucleus);GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0016787(hydrolase activity);GO:0005515(protein binding);GO:0004527(exonuclease activity);GO:0004518(nuclease activity);GO:0005730(nucleolus);GO:0005829(cytosol);GO:0019901(protein kinase binding);GO:0043488(regulation of mRNA stability);GO:0004535(poly(A)-specific ribonuclease activity);GO:0000289(nuclear-transcribed mRNA poly(A) tail shortening);GO:0006402(mRNA catabolic process);GO:0032212(positive regulation of telomere maintenance via telomerase);GO:0051973(positive regulation of telomerase activity);GO:0070034(telomerase RNA binding);GO:0000184(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay);GO:0007292(female gamete generation);GO:0090669(telomerase RNA stabilization);GO:1904872(regulation of telomerase RNA localization to Cajal body);GO:0003730(mRNA 3'-UTR binding);GO:0043169(cation binding);GO:0009451(RNA modification);GO:0090503(RNA phosphodiester bond hydrolysis, exonucleolytic);GO:0110008(ncRNA deadenylation)","03018(RNA degradation)","NA","NA","poly(A)-specific ribonuclease [Source:HGNC Symbol;Acc:HGNC:8609]",0,0,1,0,1,1,"no","no"]
[157772,0,"chr5","+",122816923,122829773,"ENST00000506847",6,798,"MSTRG.12271","SNX2","GO:0006810(transport);GO:0016020(membrane);GO:0006886(intracellular protein transport);GO:0015031(protein transport);GO:0005829(cytosol);GO:0006897(endocytosis);GO:0042995(cell projection);GO:0005515(protein binding);GO:0035091(phosphatidylinositol binding);GO:0005764(lysosome);GO:0005768(endosome);GO:0008289(lipid binding);GO:0034498(early endosome to Golgi transport);GO:0045296(cadherin binding);GO:0030027(lamellipodium);GO:0070062(extracellular exosome);GO:0043234(protein complex);GO:0019898(extrinsic component of membrane);GO:0010008(endosome membrane);GO:0042147(retrograde transport, endosome to Golgi);GO:0031901(early endosome membrane);GO:0030904(retromer complex);GO:0042803(protein homodimerization activity);GO:0046982(protein heterodimerization activity);GO:0005737(cytoplasm);GO:0051259(protein oligomerization);GO:0005154(epidermal growth factor receptor binding);GO:0005158(insulin receptor binding);GO:1990459(transferrin receptor binding);GO:1990460(leptin receptor binding);GO:0016050(vesicle organization);GO:0072673(lamellipodium morphogenesis);GO:0030905(retromer, tubulation complex);GO:0005622(intracellular)","04144(Endocytosis)","NA","NA","sorting nexin 2 [Source:HGNC Symbol;Acc:HGNC:11173]",{"v":1.001316,"d":"1.00"},{"v":0.17291,"d":"0.17"},{"v":5.79096639870453,"d":"5.79"},{"v":2.53380412581006,"d":"2.53"},1,1,"up","no"]
[98899,0,"chr19","+",19339667,19344852,"ENST00000585823",7,568,"MSTRG.8017","MAU2","GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0051301(cell division);GO:0007049(cell cycle);GO:0016604(nuclear body);GO:0003690(double-stranded DNA binding);GO:0007059(chromosome segregation);GO:0005515(protein binding);GO:0007064(mitotic sister chromatid cohesion);GO:0047485(protein N-terminus binding);GO:0000785(chromatin);GO:0034088(maintenance of mitotic sister chromatid cohesion);GO:0032116(SMC loading complex)","NA","NA","NA","MAU2 sister chromatid cohesion factor [Source:HGNC Symbol;Acc:HGNC:29140]",{"v":0.019314,"d":"0.02"},0,"inf","inf",1,1,"up","no"]
[132342,0,"chr22","-",47463467,47487088,"ENST00000481625",2,465,"ENSG00000218357","LINC01644","NA","NA","NA","NA","long intergenic non-protein coding RNA 1644 [Source:HGNC Symbol;Acc:HGNC:52431]",{"v":0.101655,"d":"0.10"},0,"inf","inf",1,1,"up","no"]
[151274,0,"chr4","+",145375543,145376253,"ENST00000536295",1,711,"ENSG00000251333","RTN3P1","NA","NA","NA","NA","reticulon 3 pseudogene 1 [Source:HGNC Symbol;Acc:HGNC:19212]",{"v":0.17812,"d":"0.18"},{"v":0.035789,"d":"0.04"},{"v":4.97694822431473,"d":"4.98"},{"v":2.31526137859361,"d":"2.32"},1,1,"up","no"]
[113294,0,"chr2","+",108730817,108731898,"ENST00000495924",2,646,"MSTRG.9031","RANBP2","GO:0003723(RNA binding);GO:0006810(transport);GO:0051028(mRNA transport);GO:0005634(nucleus);GO:0016020(membrane);GO:0015031(protein transport);GO:0043231(intracellular membrane-bounded organelle);GO:0046872(metal ion binding);GO:0031965(nuclear membrane);GO:0003755(peptidyl-prolyl cis-trans isomerase activity);GO:0000413(protein peptidyl-prolyl isomerization);GO:0006457(protein folding);GO:0043547(positive regulation of GTPase activity);GO:0016874(ligase activity);GO:0005515(protein binding);GO:0046907(intracellular transport);GO:0005643(nuclear pore);GO:0005737(cytoplasm);GO:0005096(GTPase activator activity);GO:0005813(centrosome);GO:0005829(cytosol);GO:0075733(intracellular transport of virus);GO:0043657(host cell);GO:0006607(NLS-bearing protein import into nucleus);GO:0016925(protein sumoylation);GO:0007051(spindle organization);GO:0007062(sister chromatid cohesion);GO:0019789(SUMO transferase activity);GO:0005635(nuclear envelope);GO:0016032(viral process);GO:0005642(annulate lamellae);GO:0006406(mRNA export from nucleus);GO:0060964(regulation of gene silencing by miRNA);GO:0006110(regulation of glycolytic process);GO:0006409(tRNA export from nucleus);GO:0007077(mitotic nuclear envelope disassembly);GO:0019083(viral transcription);GO:1900034(regulation of cellular response to heat);GO:0006511(ubiquitin-dependent protein catabolic process);GO:0008536(Ran GTPase binding);GO:0042405(nuclear inclusion body);GO:0006405(RNA export from nucleus);GO:0000082(G1/S transition of mitotic cell cycle);GO:0044615(nuclear pore nuclear basket);GO:0051642(centrosome localization);GO:0046604(positive regulation of mitotic centrosome separation);GO:0032403(protein complex binding);GO:0001975(response to amphetamine);GO:0033133(positive regulation of glucokinase activity);GO:0090526(regulation of gluconeogenesis involved in cellular glucose homeostasis);GO:0005739(mitochondrion);GO:0044614(nuclear pore cytoplasmic filaments);GO:1990723(cytoplasmic periphery of the nuclear pore complex)","03013(RNA transport)","NA","NA","RAN binding protein 2 [Source:HGNC Symbol;Acc:HGNC:9848]",0,0,1,0,1,1,"no","no"]
[57880,0,"chr14","+",92323605,92501483,"ENST00000532405",17,9950,"ENSG00000140090","SLC24A4","GO:0006810(transport);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0055085(transmembrane transport);GO:0006811(ion transport);GO:0005887(integral component of plasma membrane);GO:0015293(symporter activity);GO:0006813(potassium ion transport);GO:0005886(plasma membrane);GO:0015297(antiporter activity);GO:0006814(sodium ion transport);GO:0035725(sodium ion transmembrane transport);GO:0006816(calcium ion transport);GO:0007608(sensory perception of smell);GO:0050896(response to stimulus);GO:0005509(calcium ion binding);GO:0008273(calcium, potassium:sodium antiporter activity);GO:0005262(calcium channel activity);GO:0030955(potassium ion binding);GO:0031402(sodium ion binding);GO:0006874(cellular calcium ion homeostasis);GO:0097186(amelogenesis);GO:0070588(calcium ion transmembrane transport)","04740(Olfactory transduction)","K13752","NA","solute carrier family 24 member 4 [Source:HGNC Symbol;Acc:HGNC:10978]",0,{"v":0.946777,"d":"0.95"},"-inf","-inf",1,1,"down","no"]
[48528,0,"chr12","+",131711081,131725609,"ENST00000540469",4,3536,"MSTRG.3873","SFSWAP","GO:0003723(RNA binding);GO:0006396(RNA processing);GO:0006397(mRNA processing);GO:0008380(RNA splicing);GO:0005634(nucleus);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0005515(protein binding);GO:0048025(negative regulation of mRNA splicing, via spliceosome);GO:0000395(mRNA 5'-splice site recognition);GO:0000380(alternative mRNA splicing, via spliceosome)","NA","NA","NA","splicing factor SWAP homolog [Source:HGNC Symbol;Acc:HGNC:10790]",0,{"v":0.877978,"d":"0.88"},"-inf","-inf",1,1,"down","no"]
[62657,0,"chr15","+",52180093,52205334,"ENST00000559779",3,908,"ENSG00000259577","CERNA1","NA","NA","NA","NA","competing endogenous lncRNA 1 for miR-4707-5p and miR-4767 [Source:HGNC Symbol;Acc:HGNC:52664]",{"v":0.086513,"d":"0.09"},{"v":0.208418,"d":"0.21"},{"v":0.415093705917915,"d":"0.42"},{"v":-1.26849103842128,"d":"-1.27"},1,1,"down","no"]
[95919,0,"chr19","-",8332745,8334430,"ENST00000610351",2,1193,"MSTRG.7762","KANK3","NA","NA","NA","NA","KN motif and ankyrin repeat domains 3 [Source:HGNC Symbol;Acc:HGNC:24796]",{"v":0.000491,"d":"0.00"},0,"inf","inf",1,1,"up","no"]
[114233,0,"chr2","-",127638428,127664452,"ENST00000466410",9,2592,"ENSG00000072163","LIMS2","GO:0046872(metal ion binding);GO:0005925(focal adhesion);GO:0005634(nucleus);GO:0016020(membrane);GO:0005886(plasma membrane);GO:0030054(cell junction);GO:0005829(cytosol);GO:0034329(cell junction assembly);GO:0016337(single organismal cell-cell adhesion);GO:0043066(negative regulation of apoptotic process);GO:0045216(cell-cell junction organization);GO:0050680(negative regulation of epithelial cell proliferation);GO:2000178(negative regulation of neural precursor cell proliferation);GO:2000346(negative regulation of hepatocyte proliferation);GO:2001046(positive regulation of integrin-mediated signaling pathway)","NA","NA","NA","LIM zinc finger domain containing 2 [Source:HGNC Symbol;Acc:HGNC:16084]",{"v":0.043267,"d":"0.04"},{"v":0.052958,"d":"0.05"},{"v":0.817005929226935,"d":"0.82"},{"v":-0.291581546461012,"d":"-0.29"},1,1,"down","no"]
[187037,0,"chr8","+",125432209,125436928,"ENST00000520847",3,1332,"MSTRG.14546","TRIB1","GO:0005737(cytoplasm);GO:0043433(negative regulation of sequence-specific DNA binding transcription factor activity);GO:0005634(nucleus);GO:0048662(negative regulation of smooth muscle cell proliferation);GO:0005515(protein binding);GO:0004860(protein kinase inhibitor activity);GO:0032496(response to lipopolysaccharide);GO:0006469(negative regulation of protein kinase activity);GO:0032436(positive regulation of proteasomal ubiquitin-dependent protein catabolic process);GO:0043405(regulation of MAP kinase activity);GO:0031625(ubiquitin protein ligase binding);GO:0008134(transcription factor binding);GO:0014912(negative regulation of smooth muscle cell migration);GO:0031434(mitogen-activated protein kinase kinase binding);GO:0055106(ubiquitin-protein transferase regulator activity);GO:0007254(JNK cascade);GO:0031665(negative regulation of lipopolysaccharide-mediated signaling pathway);GO:0045645(positive regulation of eosinophil differentiation);GO:0045651(positive regulation of macrophage differentiation);GO:0045659(negative regulation of neutrophil differentiation);GO:0004672(protein kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation)","NA","NA","NA","tribbles pseudokinase 1 [Source:HGNC Symbol;Acc:HGNC:16891]",{"v":0.001056,"d":"0.00"},0,"inf","inf",1,1,"up","no"]
[128499,0,"chr22","-",19180733,19291661,"ENST00000615606",30,4994,"ENSG00000070371","CLTCL1","GO:0016020(membrane);GO:0006886(intracellular protein transport);GO:0016192(vesicle-mediated transport);GO:0005198(structural molecule activity);GO:0030659(cytoplasmic vesicle membrane);GO:0031410(cytoplasmic vesicle);GO:0048268(clathrin coat assembly);GO:0005905(clathrin-coated pit);GO:0030130(clathrin coat of trans-Golgi network vesicle);GO:0007165(signal transduction);GO:0005819(spindle);GO:0032051(clathrin light chain binding);GO:0071439(clathrin complex);GO:0005515(protein binding);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0061024(membrane organization);GO:0005802(trans-Golgi network);GO:0042147(retrograde transport, endosome to Golgi);GO:0005770(late endosome);GO:0004871(signal transducer activity);GO:0030136(clathrin-coated vesicle);GO:0009653(anatomical structure morphogenesis);GO:0000278(mitotic cell cycle);GO:0006898(receptor-mediated endocytosis);GO:0046326(positive regulation of glucose import);GO:0030135(coated vesicle);GO:0097443(sorting endosome);GO:0005622(intracellular);GO:0030132(clathrin coat of coated pit)","04144(Endocytosis);04142(Lysosome);04961(Endocrine and other factor-regulated calcium reabsorption);04721(Synaptic vesicle cycle);05016(Huntington's disease);05100(Bacterial invasion of epithelial cells)","NA","NA","clathrin heavy chain like 1 [Source:HGNC Symbol;Acc:HGNC:2093]",{"v":0.350794,"d":"0.35"},0,"inf","inf",1,1,"up","no"]
[89738,0,"chr17","-",82079222,82079378,"ENST00000636628",2,100,"MSTRG.7349","FASN","GO:0003723(RNA binding);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005794(Golgi apparatus);GO:0005829(cytosol);GO:0016740(transferase activity);GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0016787(hydrolase activity);GO:0003824(catalytic activity);GO:0016829(lyase activity);GO:0006629(lipid metabolic process);GO:0008152(metabolic process);GO:0009058(biosynthetic process);GO:0005886(plasma membrane);GO:0006631(fatty acid metabolic process);GO:0006633(fatty acid biosynthetic process);GO:0005515(protein binding);GO:0042470(melanosome);GO:0016788(hydrolase activity, acting on ester bonds);GO:0004315(3-oxoacyl-[acyl-carrier-protein] synthase activity);GO:0004312(fatty acid synthase activity);GO:0004313([acyl-carrier-protein] S-acetyltransferase activity);GO:0004314([acyl-carrier-protein] S-malonyltransferase activity);GO:0004316(3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity);GO:0004317(3-hydroxypalmitoyl-[acyl-carrier-protein] dehydratase activity);GO:0004319(enoyl-[acyl-carrier-protein] reductase (NADPH, B-specific) activity);GO:0004320(oleoyl-[acyl-carrier-protein] hydrolase activity);GO:0016295(myristoyl-[acyl-carrier-protein] hydrolase activity);GO:0016296(palmitoyl-[acyl-carrier-protein] hydrolase activity);GO:0016297(acyl-[acyl-carrier-protein] hydrolase activity);GO:0031177(phosphopantetheine binding);GO:0045296(cadherin binding);GO:0070062(extracellular exosome);GO:0031325(positive regulation of cellular metabolic process);GO:0045540(regulation of cholesterol biosynthetic process);GO:0046949(fatty-acyl-CoA biosynthetic process);GO:0001649(osteoblast differentiation);GO:0015939(pantothenate metabolic process);GO:0008144(drug binding);GO:0019171(3-hydroxyacyl-[acyl-carrier-protein] dehydratase activity);GO:0042802(identical protein binding);GO:0042803(protein homodimerization activity);GO:0047117(enoyl-[acyl-carrier-protein] reductase (NADPH, A-specific) activity);GO:0047451(3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity);GO:0070402(NADPH binding);GO:0102131(3-oxo-glutaryl-[acp] methyl ester reductase activity);GO:0102132(3-oxo-pimeloyl-[acp] methyl ester reductase activity);GO:0006084(acetyl-CoA metabolic process);GO:0030879(mammary gland development);GO:0071353(cellular response to interleukin-4);GO:0005739(mitochondrion);GO:0042587(glycogen granule)","00061(Fatty acid biosynthesis);04152(AMPK signaling pathway);04910(Insulin signaling pathway)","NA","NA","fatty acid synthase [Source:HGNC Symbol;Acc:HGNC:3594]",0,0,1,0,1,1,"no","no"]
[73448,0,"chr16","+",57129052,57147966,"ENST00000566910",5,938,"MSTRG.5943","CPNE2","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0070062(extracellular exosome);GO:0071277(cellular response to calcium ion)","NA","NA","NA","copine 2 [Source:HGNC Symbol;Acc:HGNC:2315]",{"v":0.960855,"d":"0.96"},{"v":0.573045,"d":"0.57"},{"v":1.67675313457058,"d":"1.68"},{"v":0.745670299070844,"d":"0.75"},1,1,"up","no"]
[89357,0,"chr17","-",81559125,81566635,"ENST00000573876",3,560,"MSTRG.7324","NPLOC4","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0005829(cytosol);GO:0005783(endoplasmic reticulum);GO:0005515(protein binding);GO:0006511(ubiquitin-dependent protein catabolic process);GO:0031625(ubiquitin protein ligase binding);GO:0030970(retrograde protein transport, ER to cytosol);GO:0005654(nucleoplasm);GO:0032480(negative regulation of type I interferon production);GO:0043130(ubiquitin binding);GO:0043161(proteasome-mediated ubiquitin-dependent protein catabolic process);GO:0070987(error-free translesion synthesis);GO:0034098(VCP-NPL4-UFD1 AAA ATPase complex);GO:0039536(negative regulation of RIG-I signaling pathway);GO:0007030(Golgi organization);GO:0030433(ubiquitin-dependent ERAD pathway);GO:0036501(UFD1-NPL4 complex);GO:0042175(nuclear outer membrane-endoplasmic reticulum membrane network)","04141(Protein processing in endoplasmic reticulum)","NA","NA","NPL4 homolog, ubiquitin recognition factor [Source:HGNC Symbol;Acc:HGNC:18261]",{"v":0.052788,"d":"0.05"},{"v":6.2e-05,"d":"0.00"},{"v":851.41935483871,"d":"851.42"},{"v":9.73372607624441,"d":"9.73"},1,1,"up","no"]
[54072,0,"chr14","+",31248628,31302739,"ENST00000551799",6,975,"ENSG00000257831","AL136418.1","NA","NA","NA","NA","NA",{"v":0.044117,"d":"0.04"},0,"inf","inf",1,1,"up","no"]
[183525,0,"chr8","+",42896946,42998156,"ENST00000527306",16,2325,"MSTRG.14338","HOOK3","GO:0006810(transport);GO:0005737(cytoplasm);GO:0015031(protein transport);GO:0005829(cytosol);GO:0005794(Golgi apparatus);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0005874(microtubule);GO:0008017(microtubule binding);GO:0005813(centrosome);GO:0008333(endosome to lysosome transport);GO:0051959(dynein light intermediate chain binding);GO:0030705(cytoskeleton-dependent intracellular transport);GO:0042802(identical protein binding);GO:0051645(Golgi localization);GO:0050768(negative regulation of neurogenesis);GO:0007040(lysosome organization);GO:0005801(cis-Golgi network);GO:0007032(endosome organization);GO:0000242(pericentriolar material);GO:0045022(early endosome to late endosome transport);GO:0030897(HOPS complex);GO:0022027(interkinetic nuclear migration);GO:0031122(cytoplasmic microtubule organization);GO:0071539(protein localization to centrosome);GO:0034454(microtubule anchoring at centrosome);GO:0097150(neuronal stem cell population maintenance);GO:0034451(centriolar satellite);GO:0070695(FHF complex)","NA","NA","NA","hook microtubule tethering protein 3 [Source:HGNC Symbol;Acc:HGNC:23576]",0,{"v":0.022076,"d":"0.02"},"-inf","-inf",1,1,"down","no"]
[190164,0,"chr9","+",36190963,36212059,"ENST00000396603",6,1090,"MSTRG.14764","CLTA","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0006886(intracellular protein transport);GO:0016192(vesicle-mediated transport);GO:0051301(cell division);GO:0005198(structural molecule activity);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0007049(cell cycle);GO:0030659(cytoplasmic vesicle membrane);GO:0031410(cytoplasmic vesicle);GO:0005905(clathrin-coated pit);GO:0030130(clathrin coat of trans-Golgi network vesicle);GO:0030132(clathrin coat of coated pit);GO:0005819(spindle);GO:0005886(plasma membrane);GO:0003674(molecular_function);GO:0005829(cytosol);GO:0061024(membrane organization);GO:0007018(microtubule-based movement);GO:0019886(antigen processing and presentation of exogenous peptide antigen via MHC class II);GO:0032588(trans-Golgi network membrane);GO:0034383(low-density lipoprotein particle clearance);GO:0036020(endolysosome membrane);GO:0032802(low-density lipoprotein particle receptor catabolic process);GO:0032050(clathrin heavy chain binding);GO:0048268(clathrin coat assembly);GO:0072583(clathrin-dependent endocytosis);GO:0030118(clathrin coat);GO:0030125(clathrin vesicle coat);GO:0071439(clathrin complex);GO:0032403(protein complex binding);GO:0042277(peptide binding);GO:0051020(GTPase binding);GO:0006897(endocytosis);GO:0030136(clathrin-coated vesicle);GO:0030672(synaptic vesicle membrane)","04144(Endocytosis);04142(Lysosome);04961(Endocrine and other factor-regulated calcium reabsorption);04721(Synaptic vesicle cycle);05016(Huntington's disease);05100(Bacterial invasion of epithelial cells)","K04644","NA","clathrin light chain A [Source:HGNC Symbol;Acc:HGNC:2090]",{"v":0.282211,"d":"0.28"},0,"inf","inf",1,1,"up","no"]
[108715,0,"chr2","-",36552258,36559255,"ENST00000475815",2,4495,"MSTRG.8621","FEZ2","GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0007399(nervous system development);GO:0007165(signal transduction);GO:0007411(axon guidance);GO:0030424(axon);GO:1902902(negative regulation of autophagosome assembly)","NA","NA","NA","fasciculation and elongation protein zeta 2 [Source:HGNC Symbol;Acc:HGNC:3660]",{"v":0.059931,"d":"0.06"},{"v":0.067931,"d":"0.07"},{"v":0.882233442758093,"d":"0.88"},{"v":-0.18076764528609,"d":"-0.18"},1,1,"down","no"]
[128805,0,"chr22","+",20550987,20564597,"ENST00000457322",5,623,"MSTRG.10158","MED15","GO:0005634(nucleus);GO:0001104(RNA polymerase II transcription cofactor activity);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0016592(mediator complex);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0005515(protein binding);GO:0005654(nucleoplasm);GO:0006367(transcription initiation from RNA polymerase II promoter)","NA","NA","NA","mediator complex subunit 15 [Source:HGNC Symbol;Acc:HGNC:14248]",{"v":0.074596,"d":"0.07"},{"v":0.147747,"d":"0.15"},{"v":0.504890116212174,"d":"0.50"},{"v":-0.985958659588367,"d":"-0.99"},1,1,"down","no"]
[120882,0,"chr2","+",240560792,240564014,"ENST00000438823",3,817,"MSTRG.9515","DUSP28","GO:0016787(hydrolase activity);GO:0008138(protein tyrosine/serine/threonine phosphatase activity);GO:0016791(phosphatase activity);GO:0006470(protein dephosphorylation);GO:0016311(dephosphorylation);GO:0004721(phosphoprotein phosphatase activity);GO:0004725(protein tyrosine phosphatase activity);GO:0035335(peptidyl-tyrosine dephosphorylation)","NA","NA","NA","dual specificity phosphatase 28 [Source:HGNC Symbol;Acc:HGNC:33237]",{"v":0.370229,"d":"0.37"},{"v":0.56337,"d":"0.56"},{"v":0.657168468324547,"d":"0.66"},{"v":-0.60566483505454,"d":"-0.61"},1,1,"down","no"]
[29611,0,"chr11","+",59755398,59805882,"ENST00000633708",11,3111,"MSTRG.2420","STX3","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0006886(intracellular protein transport);GO:0016192(vesicle-mediated transport);GO:0006887(exocytosis);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0016081(synaptic vesicle docking);GO:0005484(SNAP receptor activity);GO:0030027(lamellipodium);GO:0070062(extracellular exosome);GO:0000149(SNARE binding);GO:0031201(SNARE complex);GO:0008284(positive regulation of cell proliferation);GO:0048278(vesicle docking);GO:0031629(synaptic vesicle fusion to presynaptic active zone membrane);GO:0042581(specific granule);GO:0042582(azurophil granule);GO:0045785(positive regulation of cell adhesion);GO:0005911(cell-cell junction);GO:0006836(neurotransmitter transport);GO:0008021(synaptic vesicle);GO:0050921(positive regulation of chemotaxis);GO:2000010(positive regulation of protein localization to cell surface);GO:0030426(growth cone);GO:0043005(neuron projection);GO:1903078(positive regulation of protein localization to plasma membrane);GO:0005773(vacuole);GO:0050544(arachidonic acid binding);GO:0006906(vesicle fusion);GO:0031175(neuron projection development);GO:0060291(long-term synaptic potentiation);GO:0061025(membrane fusion);GO:0098967(exocytic insertion of neurotransmitter receptor to postsynaptic membrane);GO:0016324(apical plasma membrane);GO:0030141(secretory granule);GO:0030425(dendrite);GO:0042470(melanosome);GO:0042589(zymogen granule membrane);GO:0042734(presynaptic membrane);GO:0097470(ribbon synapse);GO:0098794(postsynapse);GO:1990796(photoreceptor cell terminal bouton);GO:0005622(intracellular);GO:0098793(presynapse)","04130(SNARE interactions in vesicular transport);04721(Synaptic vesicle cycle)","K08486","NA","syntaxin 3 [Source:HGNC Symbol;Acc:HGNC:11438]",{"v":0.27358,"d":"0.27"},{"v":0.071081,"d":"0.07"},{"v":3.84884849678536,"d":"3.85"},{"v":1.94442688308997,"d":"1.94"},1,1,"up","no"]
[158637,0,"chr5","+",136160986,136172829,"ENST00000507637",3,638,"ENSG00000113658","SMAD5","GO:0005737(cytoplasm);GO:0005634(nucleus);GO:0030509(BMP signaling pathway);GO:0016021(integral component of membrane);GO:0046872(metal ion binding);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0005622(intracellular);GO:0007165(signal transduction);GO:0007179(transforming growth factor beta receptor signaling pathway);GO:0005667(transcription factor complex);GO:0045893(positive regulation of transcription, DNA-templated);GO:0005515(protein binding);GO:0043234(protein complex);GO:0031625(ubiquitin protein ligase binding);GO:0030618(transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity);GO:0060395(SMAD protein signal transduction);GO:1901522(positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus);GO:0071141(SMAD protein complex);GO:0005057(signal transducer activity, downstream of receptor);GO:0009880(embryonic pattern specification);GO:0017151(DEAD/H-box RNA helicase binding);GO:0000977(RNA polymerase II regulatory region sequence-specific DNA binding);GO:0000979(RNA polymerase II core promoter sequence-specific DNA binding);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0001503(ossification);GO:0001657(ureteric bud development);GO:0001880(Mullerian duct regression);GO:0002051(osteoblast fate commitment);GO:0006468(protein phosphorylation);GO:0007281(germ cell development);GO:0030218(erythrocyte differentiation);GO:0045669(positive regulation of osteoblast differentiation);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0051216(cartilage development);GO:0060048(cardiac muscle contraction);GO:0060348(bone development);GO:0071407(cellular response to organic cyclic compound);GO:0071773(cellular response to BMP stimulus)","04350(TGF-beta signaling pathway);04550(Signaling pathways regulating pluripotency of stem cells)","NA","NA","SMAD family member 5 [Source:HGNC Symbol;Acc:HGNC:6771]",0,{"v":0.15844,"d":"0.16"},"-inf","-inf",1,1,"down","no"]
[41994,0,"chr12","-",53014629,53046959,"ENST00000552905",3,523,"MSTRG.3389","AC068888.1","NA","NA","NA","NA","NA",0,{"v":0.056709,"d":"0.06"},"-inf","-inf",1,1,"down","no"]
[75173,0,"chr16","+",70299178,70319709,"ENST00000562912",5,569,"MSTRG.6093","DDX19B","GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0006810(transport);GO:0051028(mRNA transport);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0015031(protein transport);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0016787(hydrolase activity);GO:0004386(helicase activity);GO:0005515(protein binding);GO:0005643(nuclear pore);GO:0005730(nucleolus);GO:0070062(extracellular exosome);GO:0004004(ATP-dependent RNA helicase activity);GO:0010501(RNA secondary structure unwinding);GO:0010468(regulation of gene expression);GO:0031965(nuclear membrane);GO:0008380(RNA splicing);GO:0071013(catalytic step 2 spliceosome);GO:0006406(mRNA export from nucleus)","NA","NA","NA","DEAD-box helicase 19B [Source:HGNC Symbol;Acc:HGNC:2742]",{"v":0.578287,"d":"0.58"},{"v":0.041737,"d":"0.04"},{"v":13.8554999161416,"d":"13.86"},{"v":3.79238686009334,"d":"3.79"},1,1,"up","no"]
[50168,0,"chr13","-",46152781,46168519,"ENST00000416500",7,819,"MSTRG.3990","LCP1","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0046872(metal ion binding);GO:0005829(cytosol);GO:0005509(calcium ion binding);GO:0003779(actin binding);GO:0005886(plasma membrane);GO:0015629(actin cytoskeleton);GO:0005856(cytoskeleton);GO:0042995(cell projection);GO:0005615(extracellular space);GO:0030054(cell junction);GO:0005925(focal adhesion);GO:0042802(identical protein binding);GO:0051015(actin filament binding);GO:0031100(animal organ regeneration);GO:0051017(actin filament bundle assembly);GO:0001726(ruffle);GO:0001891(phagocytic cup);GO:0005884(actin filament);GO:0030175(filopodium);GO:0070062(extracellular exosome);GO:0022617(extracellular matrix disassembly);GO:0002102(podosome);GO:0001725(stress fiber);GO:0032587(ruffle membrane);GO:0035722(interleukin-12-mediated signaling pathway);GO:0016477(cell migration);GO:0051639(actin filament network formation);GO:0051020(GTPase binding);GO:0032432(actin filament bundle);GO:0002286(T cell activation involved in immune response);GO:0010737(protein kinase A signaling);GO:0033157(regulation of intracellular protein transport);GO:0051764(actin crosslink formation);GO:0071803(positive regulation of podosome assembly)","NA","NA","NA","lymphocyte cytosolic protein 1 [Source:HGNC Symbol;Acc:HGNC:6528]",0,0,1,0,1,1,"no","no"]
[42519,0,"chr12","+",54574757,54577236,"ENST00000552774",5,796,"ENSG00000123360","PDE1B","GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0005634(nucleus);GO:0005829(cytosol);GO:0016787(hydrolase activity);GO:0007165(signal transduction);GO:0005515(protein binding);GO:0008081(phosphoric diester hydrolase activity);GO:0004112(cyclic-nucleotide phosphodiesterase activity);GO:0004114(3',5'-cyclic-nucleotide phosphodiesterase activity);GO:0004115(3',5'-cyclic-AMP phosphodiesterase activity);GO:0048101(calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity);GO:0001505(regulation of neurotransmitter levels);GO:0001975(response to amphetamine);GO:0006198(cAMP catabolic process);GO:0007626(locomotory behavior);GO:0008542(visual learning);GO:0042053(regulation of dopamine metabolic process);GO:0042428(serotonin metabolic process);GO:0046069(cGMP catabolic process);GO:0043025(neuronal cell body);GO:0005516(calmodulin binding);GO:0006915(apoptotic process);GO:0047555(3',5'-cyclic-GMP phosphodiesterase activity);GO:0036006(cellular response to macrophage colony-stimulating factor stimulus);GO:0030224(monocyte differentiation);GO:0097011(cellular response to granulocyte macrophage colony-stimulating factor stimulus);GO:0004117(calmodulin-dependent cyclic-nucleotide phosphodiesterase activity)","00230(Purine metabolism);04020(Calcium signaling pathway);04924(Renin secretion);04740(Olfactory transduction);04742(Taste transduction);05032(Morphine addiction)","NA","NA","phosphodiesterase 1B [Source:HGNC Symbol;Acc:HGNC:8775]",{"v":0.43904,"d":"0.44"},{"v":0.348963,"d":"0.35"},{"v":1.25812765250184,"d":"1.26"},{"v":0.331278308773813,"d":"0.33"},1,1,"up","no"]
[33128,0,"chr11","-",74909919,74949075,"ENST00000533598",8,872,"MSTRG.2710","XRRA1","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005654(nucleoplasm);GO:0016604(nuclear body);GO:0003674(molecular_function);GO:0010165(response to X-ray)","NA","NA","NA","X-ray radiation resistance associated 1 [Source:HGNC Symbol;Acc:HGNC:18868]",{"v":0.176662,"d":"0.18"},{"v":0.370549,"d":"0.37"},{"v":0.476757459877101,"d":"0.48"},{"v":-1.06867258216265,"d":"-1.07"},1,1,"down","no"]
[88803,0,"chr17","+",78342737,78344357,"ENST00000586583",2,643,"ENSG00000267737","AC087645.2","NA","NA","NA","NA","NA",{"v":0.247837,"d":"0.25"},{"v":0.103862,"d":"0.10"},{"v":2.38621439987676,"d":"2.39"},{"v":1.25472367410721,"d":"1.25"},1,1,"up","no"]
[70815,0,"chr16","-",23474953,23480423,"ENST00000569182",5,587,"MSTRG.5751","GGA2","GO:0006810(transport);GO:0016020(membrane);GO:0006886(intracellular protein transport);GO:0015031(protein transport);GO:0016192(vesicle-mediated transport);GO:0005794(Golgi apparatus);GO:0005622(intracellular);GO:0030131(clathrin adaptor complex);GO:0005515(protein binding);GO:0005768(endosome);GO:0044267(cellular protein metabolic process);GO:0061024(membrane organization);GO:0005802(trans-Golgi network);GO:0010008(endosome membrane);GO:0030136(clathrin-coated vesicle);GO:0030306(ADP-ribosylation factor binding);GO:0031901(early endosome membrane)","04142(Lysosome)","NA","NA","golgi associated, gamma adaptin ear containing, ARF binding protein 2 [Source:HGNC Symbol;Acc:HGNC:16064]",0,{"v":0.313023,"d":"0.31"},"-inf","-inf",1,1,"down","no"]
[68094,0,"chr16","-",1963212,1964841,"ENST00000563194",3,170,"MSTRG.5529","RPS2","GO:0003723(RNA binding);GO:0005634(nucleus);GO:0016020(membrane);GO:0006412(translation);GO:0030529(intracellular ribonucleoprotein complex);GO:0003735(structural constituent of ribosome);GO:0005840(ribosome);GO:0015935(small ribosomal subunit);GO:0005515(protein binding);GO:0022627(cytosolic small ribosomal subunit);GO:0005654(nucleoplasm);GO:0005925(focal adhesion);GO:0003729(mRNA binding);GO:0005829(cytosol);GO:0045296(cadherin binding);GO:0070062(extracellular exosome);GO:0019899(enzyme binding);GO:0006413(translational initiation);GO:0006364(rRNA processing);GO:0000184(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay);GO:0019083(viral transcription);GO:0006479(protein methylation);GO:0006614(SRP-dependent cotranslational protein targeting to membrane);GO:0017134(fibroblast growth factor binding);GO:0051347(positive regulation of transferase activity)","03010(Ribosome)","NA","NA","ribosomal protein S2 [Source:HGNC Symbol;Acc:HGNC:10404]",{"v":0.390473,"d":"0.39"},{"v":0.391715,"d":"0.39"},{"v":0.996829327444698,"d":"1.00"},{"v":-0.0045815807623872,"d":"-0.00"},1,1,"down","no"]
[25870,0,"chr11","+",5402597,5403547,"ENST00000332043",1,951,"MSTRG.2165","OR51J1","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0004930(G-protein coupled receptor activity);GO:0007186(G-protein coupled receptor signaling pathway);GO:0005886(plasma membrane);GO:0004871(signal transducer activity);GO:0007165(signal transduction);GO:0004984(olfactory receptor activity);GO:0007608(sensory perception of smell);GO:0050896(response to stimulus);GO:0050911(detection of chemical stimulus involved in sensory perception of smell)","NA","NA","NA","olfactory receptor family 51 subfamily J member 1 (gene/pseudogene) [Source:HGNC Symbol;Acc:HGNC:14856]",0,0,1,0,1,1,"no","no"]
[88713,0,"chr17","-",78112922,78113959,"ENST00000590494",2,702,"MSTRG.7280","TMC6","GO:0006810(transport);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005794(Golgi apparatus);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0006811(ion transport);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0008150(biological_process);GO:0070062(extracellular exosome);GO:0043312(neutrophil degranulation);GO:0035579(specific granule membrane);GO:0070821(tertiary granule membrane);GO:0031965(nuclear membrane)","NA","NA","NA","transmembrane channel like 6 [Source:HGNC Symbol;Acc:HGNC:18021]",{"v":0.271374,"d":"0.27"},0,"inf","inf",1,1,"up","no"]
[107591,0,"chr2","-",19352012,19356912,"ENST00000487581",2,4171,"ENSG00000143867","OSR1","GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0010628(positive regulation of gene expression);GO:0007507(heart development);GO:0030154(cell differentiation);GO:0048863(stem cell differentiation);GO:0043066(negative regulation of apoptotic process);GO:0030501(positive regulation of bone mineralization);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0005515(protein binding);GO:0005829(cytosol);GO:0060021(palate development);GO:0030857(negative regulation of epithelial cell differentiation);GO:0035115(embryonic forelimb morphogenesis);GO:0035116(embryonic hindlimb morphogenesis);GO:0042733(embryonic digit morphogenesis);GO:0072498(embryonic skeletal joint development);GO:0001823(mesonephros development);GO:0050679(positive regulation of epithelial cell proliferation);GO:0042474(middle ear morphogenesis);GO:0072162(metanephric mesenchymal cell differentiation);GO:0019901(protein kinase binding);GO:0004674(protein serine/threonine kinase activity);GO:0001657(ureteric bud development);GO:0018107(peptidyl-threonine phosphorylation);GO:0060272(embryonic skeletal joint morphogenesis);GO:0042476(odontogenesis);GO:0072075(metanephric mesenchyme development);GO:0072166(posterior mesonephric tubule development);GO:0072207(metanephric epithelium development);GO:0001655(urogenital system development);GO:2000543(positive regulation of gastrulation);GO:0036023(embryonic skeletal limb joint morphogenesis);GO:0048793(pronephros development);GO:0019898(extrinsic component of membrane);GO:0072208(metanephric smooth muscle tissue development);GO:0002062(chondrocyte differentiation);GO:0001656(metanephros development);GO:0007231(osmosensory signaling pathway);GO:0008406(gonad development);GO:0023016(signal transduction by trans-phosphorylation);GO:0048389(intermediate mesoderm development);GO:0071300(cellular response to retinoic acid);GO:0072111(cell proliferation involved in kidney development);GO:0072133(metanephric mesenchyme morphogenesis);GO:0072143(mesangial cell development);GO:0072168(specification of anterior mesonephric tubule identity);GO:0072169(specification of posterior mesonephric tubule identity);GO:0072180(mesonephric duct morphogenesis);GO:0072183(negative regulation of nephron tubule epithelial cell differentiation);GO:0072184(renal vesicle progenitor cell differentiation);GO:0072190(ureter urothelium development);GO:0072234(metanephric nephron tubule development);GO:0072239(metanephric glomerulus vasculature development);GO:0072259(metanephric interstitial fibroblast development);GO:0072268(pattern specification involved in metanephros development);GO:0090094(metanephric cap mesenchymal cell proliferation involved in metanephros development);GO:1905408(negative regulation of creatine transmembrane transporter activity);GO:2000650(negative regulation of sodium ion transmembrane transporter activity)","NA","NA","NA","odd-skipped related transciption factor 1 [Source:HGNC Symbol;Acc:HGNC:8111]",0,0,1,0,1,1,"no","no"]
[188733,0,"chr9","+",2068953,2193624,"ENST00000635739",26,4272,"MSTRG.14677","SMARCA2","GO:0016514(SWI/SNF complex);GO:0016887(ATPase activity);GO:0006338(chromatin remodeling);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0005634(nucleus);GO:0043231(intracellular membrane-bounded organelle);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0005654(nucleoplasm);GO:0006355(regulation of transcription, DNA-templated);GO:0016787(hydrolase activity);GO:0006351(transcription, DNA-templated);GO:0004386(helicase activity);GO:0003677(DNA binding);GO:0045111(intermediate filament cytoskeleton);GO:0005515(protein binding);GO:0007399(nervous system development);GO:0045893(positive regulation of transcription, DNA-templated);GO:0042393(histone binding);GO:0016817(hydrolase activity, acting on acid anhydrides);GO:0008285(negative regulation of cell proliferation);GO:0003713(transcription coactivator activity);GO:0044212(transcription regulatory region DNA binding);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0000790(nuclear chromatin);GO:0045892(negative regulation of transcription, DNA-templated);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0071564(npBAF complex);GO:0071565(nBAF complex);GO:0001105(RNA polymerase II transcription coactivator activity);GO:0030308(negative regulation of cell growth);GO:0008094(DNA-dependent ATPase activity);GO:0003682(chromatin binding);GO:0007286(spermatid development)","05225(Hepatocellular carcinoma)","NA","NA","SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 [Source:HGNC Symbol;Acc:HGNC:11098]",{"v":0.036812,"d":"0.04"},{"v":0.059626,"d":"0.06"},{"v":0.617381679133264,"d":"0.62"},{"v":-0.695765423427293,"d":"-0.70"},1,1,"down","no"]
[103753,0,"chr19","+",49086480,49098459,"ENST00000601411",5,377,"MSTRG.8303","SNRNP70","GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0006397(mRNA processing);GO:0005634(nucleus);GO:0016607(nuclear speck);GO:0005654(nucleoplasm);GO:0030529(intracellular ribonucleoprotein complex);GO:0030619(U1 snRNA binding);GO:0005515(protein binding);GO:0005681(spliceosomal complex);GO:0005685(U1 snRNP);GO:0003729(mRNA binding);GO:0043484(regulation of RNA splicing);GO:0000398(mRNA splicing, via spliceosome);GO:0008380(RNA splicing);GO:0071011(precatalytic spliceosome);GO:0071004(U2-type prespliceosome);GO:0043462(regulation of ATPase activity);GO:0061084(negative regulation of protein refolding);GO:1904715(negative regulation of chaperone-mediated autophagy);GO:0000243(commitment complex);GO:0019013(viral nucleocapsid);GO:1990446(U1 snRNP binding);GO:0048026(positive regulation of mRNA splicing, via spliceosome);GO:0071300(cellular response to retinoic acid);GO:0071356(cellular response to tumor necrosis factor);GO:0071560(cellular response to transforming growth factor beta stimulus);GO:0005737(cytoplasm)","03040(Spliceosome)","NA","NA","small nuclear ribonucleoprotein U1 subunit 70 [Source:HGNC Symbol;Acc:HGNC:11150]",{"v":0.09126,"d":"0.09"},{"v":0.000564,"d":"0.00"},{"v":161.808510638298,"d":"161.81"},{"v":7.33814368093422,"d":"7.34"},1,1,"up","no"]
[1631,0,"chr1","+",11843861,11848079,"ENST00000400892",3,936,"ENSG00000242349","NPPA-AS1","NA","NA","NA","NA","NPPA antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:37635]",{"v":0.336503,"d":"0.34"},0,"inf","inf",1,1,"up","no"]
[53744,0,"chr14","-",24318364,24332484,"ENST00000554577",19,5276,"ENSG00000129467","ADCY4","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0035556(intracellular signal transduction);GO:0016829(lyase activity);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0016849(phosphorus-oxygen lyase activity);GO:0006171(cAMP biosynthetic process);GO:0009190(cyclic nucleotide biosynthetic process);GO:0007165(signal transduction);GO:0007193(adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway);GO:0004016(adenylate cyclase activity);GO:0004383(guanylate cyclase activity);GO:0003091(renal water homeostasis);GO:0006182(cGMP biosynthetic process);GO:0007189(adenylate cyclase-activating G-protein coupled receptor signaling pathway);GO:0007190(activation of adenylate cyclase activity);GO:0034199(activation of protein kinase A activity);GO:0071377(cellular response to glucagon stimulus);GO:0008074(guanylate cyclase complex, soluble);GO:0007188(adenylate cyclase-modulating G-protein coupled receptor signaling pathway);GO:0005622(intracellular);GO:0030425(dendrite)","00230(Purine metabolism);04015(Rap1 signaling pathway);04371(Apelin signaling pathway);04020(Calcium signaling pathway);04072(Phospholipase D signaling pathway);04024(cAMP signaling pathway);04022(cGMP - PKG signaling pathway);04114(Oocyte meiosis);04540(Gap junction);04611(Platelet activation);04062(Chemokine signaling pathway);04911(Insulin secretion);04923(Regulation of lipolysis in adipocyte);04912(GnRH signaling pathway);04913(Ovarian Steroidogenesis);04915(Estrogen signaling pathway);04914(Progesterone-mediated oocyte maturation);04921(Oxytocin signaling pathway);04926(Relaxin signaling pathway);04918(Thyroid hormone synthesis);04916(Melanogenesis);04925(Aldosterone synthesis and secretion);04927(Cortisol synthesis and secretion);04261(Adrenergic signaling in cardiomyocytes);04270(Vascular smooth muscle contraction);04970(Salivary secretion);04971(Gastric acid secretion);04972(Pancreatic secretion);04976(Bile secretion);04724(Glutamatergic synapse);04727(GABAergic synapse);04725(Cholinergic synapse);04723(Retrograde endocannabinoid signaling);04742(Taste transduction);04750(Inflammatory mediator regulation of TRP channels);04211(Longevity regulating pathway - mammal);04213(Longevity regulating pathway - multiple species);04713(Circadian entrainment);05200(Pathways in cancer);05032(Morphine addiction);05414(Dilated cardiomyopathy (DCM));05166(HTLV-I infection);01522(Endocrine resistance)","NA","NA","adenylate cyclase 4 [Source:HGNC Symbol;Acc:HGNC:235]",{"v":0.402013,"d":"0.40"},{"v":0.124126,"d":"0.12"},{"v":3.23874933535279,"d":"3.24"},{"v":1.6954368143395,"d":"1.70"},1,1,"up","no"]
[168419,0,"chr6","+",110874784,110895708,"ENST00000368882",5,3059,"MSTRG.13218","AMD1","GO:0016829(lyase activity);GO:0016831(carboxy-lyase activity);GO:0005829(cytosol);GO:0004014(adenosylmethionine decarboxylase activity);GO:0006597(spermine biosynthetic process);GO:0008295(spermidine biosynthetic process);GO:0006596(polyamine biosynthetic process);GO:0006595(polyamine metabolic process);GO:0019810(putrescine binding);GO:0006557(S-adenosylmethioninamine biosynthetic process);GO:0046500(S-adenosylmethionine metabolic process)","00270(Cysteine and methionine metabolism);00330(Arginine and proline metabolism)","K01611","EC:4.1.1.50","adenosylmethionine decarboxylase 1 [Source:HGNC Symbol;Acc:HGNC:457]",0,{"v":0.145609,"d":"0.15"},"-inf","-inf",1,1,"down","no"]
[164105,0,"chr6","+",30651054,30653109,"ENST00000465699",3,692,"MSTRG.12825","C6orf136","GO:0016020(membrane);GO:0016021(integral component of membrane)","NA","NA","NA","chromosome 6 open reading frame 136 [Source:HGNC Symbol;Acc:HGNC:21301]",{"v":0.275672,"d":"0.28"},{"v":0.086341,"d":"0.09"},{"v":3.19282843608483,"d":"3.19"},{"v":1.67483503300212,"d":"1.67"},1,1,"up","no"]
[28218,0,"chr11","+",43335279,43339373,"ENST00000529334",3,346,"MSTRG.2329","API5","GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016607(nuclear speck);GO:0016020(membrane);GO:0005515(protein binding);GO:0005681(spliceosomal complex);GO:0006915(apoptotic process);GO:0043066(negative regulation of apoptotic process);GO:0017134(fibroblast growth factor binding);GO:2000270(negative regulation of fibroblast apoptotic process)","NA","NA","NA","apoptosis inhibitor 5 [Source:HGNC Symbol;Acc:HGNC:594]",{"v":0.461659,"d":"0.46"},{"v":0.330601,"d":"0.33"},{"v":1.39642348329255,"d":"1.40"},{"v":0.481736523636671,"d":"0.48"},1,1,"up","no"]
[104434,0,"chr19","-",50792685,50793584,"ENST00000594114",2,260,"ENSG00000268375","AC010325.2","NA","NA","NA","NA","NA",0,0,1,0,1,1,"no","no"]
[135927,0,"chr3","-",48603563,48609636,"ENST00000412343",6,778,"MSTRG.10907","UQCRC1","GO:0016020(membrane);GO:0005829(cytosol);GO:0055114(oxidation-reduction process);GO:0005739(mitochondrion);GO:0005743(mitochondrial inner membrane);GO:0046872(metal ion binding);GO:0003824(catalytic activity);GO:1902600(hydrogen ion transmembrane transport);GO:0070469(respiratory chain);GO:0006122(mitochondrial electron transport, ubiquinol to cytochrome c);GO:0005750(mitochondrial respiratory chain complex III);GO:0008270(zinc ion binding);GO:0031625(ubiquitin protein ligase binding);GO:0004222(metalloendopeptidase activity);GO:0016485(protein processing);GO:0009060(aerobic respiration);GO:0008121(ubiquinol-cytochrome-c reductase activity);GO:0006119(oxidative phosphorylation);GO:0005746(mitochondrial respiratory chain);GO:0032403(protein complex binding);GO:0014823(response to activity);GO:0043279(response to alkaloid);GO:0043209(myelin sheath)","00190(Oxidative phosphorylation);04260(Cardiac muscle contraction);05010(Alzheimer's disease);05012(Parkinson's disease);05016(Huntington's disease);04932(Non-alcoholic fatty liver disease (NAFLD))","NA","NA","ubiquinol-cytochrome c reductase core protein I [Source:HGNC Symbol;Acc:HGNC:12585]",{"v":0.104126,"d":"0.10"},{"v":0.24712,"d":"0.25"},{"v":0.421358044674652,"d":"0.42"},{"v":-1.24688142513934,"d":"-1.25"},1,1,"down","no"]
[199188,0,"chrX","+",106639294,106640582,"ENST00000478395",2,425,"ENSG00000147231","CXorf57","GO:0003723(RNA binding);GO:0005515(protein binding)","NA","NA","NA","chromosome X open reading frame 57 [Source:HGNC Symbol;Acc:HGNC:25486]",{"v":0.055147,"d":"0.06"},0,"inf","inf",1,1,"up","no"]
[86090,0,"chr17","+",58337336,58351743,"ENST00000582348",3,558,"MSTRG.7060","TSPOAP1-AS1","NA","NA","NA","NA","TSPOAP1 antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:44148]",{"v":0.598466,"d":"0.60"},{"v":0.761878,"d":"0.76"},{"v":0.785514216186844,"d":"0.79"},{"v":-0.348290709327576,"d":"-0.35"},1,1,"down","no"]
[153445,0,"chr5","+",10249929,10265078,"ENST00000503026",11,1933,"MSTRG.11967","CCT5","GO:0005737(cytoplasm);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0005730(nucleolus);GO:0005829(cytosol);GO:0006457(protein folding);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0005874(microtubule);GO:0051082(unfolded protein binding);GO:0005815(microtubule organizing center);GO:0061077(chaperone-mediated protein folding);GO:0070062(extracellular exosome);GO:0009615(response to virus);GO:0050821(protein stabilization);GO:0032212(positive regulation of telomere maintenance via telomerase);GO:0048487(beta-tubulin binding);GO:0005813(centrosome);GO:1904851(positive regulation of establishment of protein localization to telomere);GO:1904874(positive regulation of telomerase RNA localization to Cajal body);GO:0003730(mRNA 3'-UTR binding);GO:0048027(mRNA 5'-UTR binding);GO:0031681(G-protein beta-subunit binding);GO:0044183(protein binding involved in protein folding);GO:0006458('de novo' protein folding);GO:1904871(positive regulation of protein localization to Cajal body);GO:0005832(chaperonin-containing T-complex);GO:0007339(binding of sperm to zona pellucida);GO:1901998(toxin transport);GO:0002199(zona pellucida receptor complex);GO:0043209(myelin sheath);GO:0044297(cell body)","NA","NA","NA","chaperonin containing TCP1 subunit 5 [Source:HGNC Symbol;Acc:HGNC:1618]",0,0,1,0,1,1,"no","no"]
[31182,0,"chr11","-",65375195,65383701,"ENST00000526898",10,3088,"ENSG00000162241","SLC25A45","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0055085(transmembrane transport);GO:0005743(mitochondrial inner membrane);GO:0005739(mitochondrion);GO:0006839(mitochondrial transport);GO:0022857(transmembrane transporter activity)","NA","NA","NA","solute carrier family 25 member 45 [Source:HGNC Symbol;Acc:HGNC:27442]",{"v":0.034404,"d":"0.03"},{"v":0.126275,"d":"0.13"},{"v":0.272452979607998,"d":"0.27"},{"v":-1.87592082624425,"d":"-1.88"},1,1,"down","no"]
[122808,0,"chr20","-",31721655,31723989,"ENST00000420488",2,820,"MSTRG.9635","BCL2L1","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005743(mitochondrial inner membrane);GO:0042981(regulation of apoptotic process);GO:0005829(cytosol);GO:0005739(mitochondrion);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0006915(apoptotic process);GO:0030054(cell junction);GO:0045202(synapse);GO:0005741(mitochondrial outer membrane);GO:0031410(cytoplasmic vesicle);GO:0005759(mitochondrial matrix);GO:0005813(centrosome);GO:0005815(microtubule organizing center);GO:0042802(identical protein binding);GO:0006897(endocytosis);GO:0019901(protein kinase binding);GO:0051434(BH3 domain binding);GO:0043066(negative regulation of apoptotic process);GO:0031965(nuclear membrane);GO:0030672(synaptic vesicle membrane);GO:0000910(cytokinesis);GO:2001240(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand);GO:0042803(protein homodimerization activity);GO:1902042(negative regulation of extrinsic apoptotic signaling pathway via death domain receptors);GO:0007093(mitotic cell cycle checkpoint);GO:2001244(positive regulation of intrinsic apoptotic signaling pathway);GO:1902230(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage);GO:0090201(negative regulation of release of cytochrome c from mitochondria);GO:0001836(release of cytochrome c from mitochondria);GO:1900118(negative regulation of execution phase of apoptosis);GO:0034097(response to cytokine);GO:0046902(regulation of mitochondrial membrane permeability);GO:0051881(regulation of mitochondrial membrane potential);GO:0046982(protein heterodimerization activity);GO:0090005(negative regulation of establishment of protein localization to plasma membrane);GO:0008637(apoptotic mitochondrial changes);GO:0097136(Bcl-2 family protein complex);GO:0019050(suppression by virus of host apoptotic process);GO:2001243(negative regulation of intrinsic apoptotic signaling pathway);GO:0001541(ovarian follicle development);GO:0001701(in utero embryonic development);GO:0007281(germ cell development);GO:0007283(spermatogenesis);GO:0008283(cell proliferation);GO:0008284(positive regulation of cell proliferation);GO:0008584(male gonad development);GO:0008630(intrinsic apoptotic signaling pathway in response to DNA damage);GO:0009314(response to radiation);GO:0009566(fertilization);GO:0009615(response to virus);GO:0040007(growth);GO:0043065(positive regulation of apoptotic process);GO:0043524(negative regulation of neuron apoptotic process);GO:0046898(response to cycloheximide);GO:0051402(neuron apoptotic process);GO:0060154(cellular process regulating host cell cycle in response to virus);GO:0070584(mitochondrion morphogenesis);GO:0071230(cellular response to amino acid stimulus);GO:0071312(cellular response to alkaloid);GO:0071480(cellular response to gamma radiation);GO:0071839(apoptotic process in bone marrow);GO:0097192(extrinsic apoptotic signaling pathway in absence of ligand);GO:0097284(hepatocyte apoptotic process);GO:0005622(intracellular);GO:0005783(endoplasmic reticulum);GO:0031966(mitochondrial membrane)","04014(Ras signaling pathway);04630(Jak-STAT signaling pathway);04064(NF-kappa B signaling pathway);04151(PI3K-Akt signaling pathway);04140(Autophagy - animal);04137(Mitophagy - animal);04210(Apoptosis);04215(Apoptosis - multiple species);04621(NOD-like receptor signaling pathway);05200(Pathways in cancer);05202(Transcriptional misregulation in cancers);05212(Pancreatic cancer);05225(Hepatocellular carcinoma);05220(Chronic myeloid leukemia);05222(Small cell lung cancer);05014(Amyotrophic lateral sclerosis (ALS));05166(HTLV-I infection);05145(Toxoplasmosis);01521(EGFR tyrosine kinase inhibitor resistance);01524(Platinum drug resistance)","K04570","NA","BCL2 like 1 [Source:HGNC Symbol;Acc:HGNC:992]",{"v":0.306742,"d":"0.31"},{"v":0.213198,"d":"0.21"},{"v":1.43876584208107,"d":"1.44"},{"v":0.524831813789977,"d":"0.52"},1,1,"up","no"]
[171522,0,"chr7","+",5216172,5225854,"ENST00000480238",6,470,"MSTRG.13466","WIPI2","GO:0016020(membrane);GO:0006914(autophagy);GO:0005829(cytosol);GO:0005515(protein binding);GO:0032266(phosphatidylinositol-3-phosphate binding);GO:0080025(phosphatidylinositol-3,5-bisphosphate binding);GO:0000045(autophagosome assembly);GO:0034497(protein localization to pre-autophagosomal structure);GO:0061739(protein lipidation involved in autophagosome assembly);GO:0098792(xenophagy);GO:0000407(pre-autophagosomal structure);GO:0005776(autophagosome);GO:0034045(pre-autophagosomal structure membrane);GO:0000422(mitophagy);GO:0006497(protein lipidation);GO:0044804(nucleophagy);GO:0019898(extrinsic component of membrane);GO:0016236(macroautophagy);GO:0043234(protein complex)","04140(Autophagy - animal);04136(Autophagy - other eukaryotes)","NA","NA","WD repeat domain, phosphoinositide interacting 2 [Source:HGNC Symbol;Acc:HGNC:32225]",0,0,1,0,1,1,"no","no"]
[54233,0,"chr14","-",34963708,34982532,"ENST00000556705",3,580,"MSTRG.4318","SRP54-AS1","NA","NA","NA","NA","SRP54 antisense RNA 1 (head to head) [Source:HGNC Symbol;Acc:HGNC:50643]",0,{"v":0.101763,"d":"0.10"},"-inf","-inf",1,1,"down","no"]
[128044,0,"chr21","-",46235126,46285394,"ENST00000291688",28,6193,"MSTRG.10092","MCM3AP","GO:0003676(nucleic acid binding);GO:0006810(transport);GO:0051028(mRNA transport);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0015031(protein transport);GO:0005829(cytosol);GO:0016740(transferase activity);GO:0031965(nuclear membrane);GO:0016746(transferase activity, transferring acyl groups);GO:0005643(nuclear pore);GO:0005654(nucleoplasm);GO:0002376(immune system process);GO:0003677(DNA binding);GO:0005635(nuclear envelope);GO:0006606(protein import into nucleus)","NA","NA","NA","minichromosome maintenance complex component 3 associated protein [Source:HGNC Symbol;Acc:HGNC:6946]",{"v":1.91485,"d":"1.91"},0,"inf","inf",1,1,"up","no"]
[181735,0,"chr8","-",18527301,19013686,"ENST00000327040",16,11689,"ENSG00000156011","PSD3","GO:0016020(membrane);GO:0005886(plasma membrane);GO:0043547(positive regulation of GTPase activity);GO:0042995(cell projection);GO:0030054(cell junction);GO:0045202(synapse);GO:0045211(postsynaptic membrane);GO:0005086(ARF guanyl-nucleotide exchange factor activity);GO:0032012(regulation of ARF protein signal transduction);GO:0005085(guanyl-nucleotide exchange factor activity);GO:0032587(ruffle membrane);GO:0014069(postsynaptic density);GO:0005543(phospholipid binding)","04144(Endocytosis)","K12494","NA","pleckstrin and Sec7 domain containing 3 [Source:HGNC Symbol;Acc:HGNC:19093]",0,0,1,0,1,1,"no","no"]
[12228,0,"chr1","-",156806244,156816848,"ENST00000392306",9,1673,"MSTRG.1089","SH2D2A","GO:0005737(cytoplasm);GO:0009967(positive regulation of signal transduction);GO:0005515(protein binding);GO:0007275(multicellular organism development);GO:0030154(cell differentiation);GO:0005829(cytosol);GO:0017124(SH3 domain binding);GO:0007165(signal transduction);GO:0048010(vascular endothelial growth factor receptor signaling pathway);GO:0001525(angiogenesis);GO:0005070(SH3/SH2 adaptor activity);GO:0008283(cell proliferation)","04370(VEGF signaling pathway)","K08273","NA","SH2 domain containing 2A [Source:HGNC Symbol;Acc:HGNC:10821]",{"v":0.236976,"d":"0.24"},{"v":0.155157,"d":"0.16"},{"v":1.52733038148456,"d":"1.53"},{"v":0.611012169648821,"d":"0.61"},1,1,"up","no"]
[31171,0,"chr11","+",65343505,65344095,"ENST00000532492",2,438,"MSTRG.2541","DPF2","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0043231(intracellular membrane-bounded organelle);GO:0046872(metal ion binding);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0000790(nuclear chromatin);GO:0005813(centrosome);GO:0005515(protein binding);GO:0006915(apoptotic process);GO:0097190(apoptotic signaling pathway);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding)","NA","NA","NA","double PHD fingers 2 [Source:HGNC Symbol;Acc:HGNC:9964]",{"v":1.012419,"d":"1.01"},{"v":0.241074,"d":"0.24"},{"v":4.19961920406182,"d":"4.20"},{"v":2.07025851900623,"d":"2.07"},1,1,"up","no"]
[38339,0,"chr12","-",7368837,7369493,"ENST00000545597",2,266,"MSTRG.3094","CD163L1","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005886(plasma membrane);GO:0005576(extracellular region);GO:0005044(scavenger receptor activity);GO:0006898(receptor-mediated endocytosis)","NA","NA","NA","CD163 molecule like 1 [Source:HGNC Symbol;Acc:HGNC:30375]",0,0,1,0,1,1,"no","no"]
[105915,0,"chr19","+",55481197,55484373,"ENST00000391718",1,3177,"ENSG00000197483","ZNF628","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding)","NA","NA","NA","zinc finger protein 628 [Source:HGNC Symbol;Acc:HGNC:28054]",{"v":1.8E-5,"d":"0.00"},0,"inf","inf",1,1,"up","no"]
[106,"j","chr1","-",726126,740555,"MSTRG.36.16",8,4610,"MSTRG.36","AL669831.1","NA","NA","NA","NA","NA",{"v":6.242223,"d":"6.24"},{"v":0.129128,"d":"0.13"},{"v":48.3413589616505,"d":"48.34"},{"v":5.5951861252866,"d":"5.60"},1,1,"up","no"]
[174198,0,"chr7","+",55978907,56000178,"ENST00000497279",7,4255,"MSTRG.13648","NIPSNAP2","GO:0005737(cytoplasm);GO:0005739(mitochondrion);GO:0005515(protein binding);GO:0005887(integral component of plasma membrane);GO:0016020(membrane);GO:0006119(oxidative phosphorylation);GO:0006754(ATP biosynthetic process);GO:1901843(positive regulation of high voltage-gated calcium channel activity);GO:2000984(negative regulation of ATP citrate synthase activity)","NA","NA","NA","nipsnap homolog 2 [Source:HGNC Symbol;Acc:HGNC:4179]",{"v":0.077345,"d":"0.08"},{"v":0.249579,"d":"0.25"},{"v":0.309901874757091,"d":"0.31"},{"v":-1.69011661232665,"d":"-1.69"},1,1,"down","no"]
[124133,0,"chr20","+",45419906,45426018,"ENST00000639872",7,1498,"MSTRG.9792","PIGT","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0006506(GPI anchor biosynthetic process);GO:0005515(protein binding);GO:0016255(attachment of GPI anchor to protein);GO:0042765(GPI-anchor transamidase complex);GO:0030176(integral component of endoplasmic reticulum membrane);GO:0003923(GPI-anchor transamidase activity);GO:0030182(neuron differentiation);GO:0051402(neuron apoptotic process);GO:0005737(cytoplasm);GO:0031410(cytoplasmic vesicle)","00563(Glycosylphosphatidylinositol(GPI)-anchor biosynthesis)","NA","NA","phosphatidylinositol glycan anchor biosynthesis class T [Source:HGNC Symbol;Acc:HGNC:14938]",{"v":0.179455,"d":"0.18"},{"v":0.193136,"d":"0.19"},{"v":0.929163905227405,"d":"0.93"},{"v":-0.105994983315818,"d":"-0.11"},1,1,"down","no"]
[27421,0,"chr11","+",22342977,22360965,"ENST00000534115",3,573,"ENSG00000091664","SLC17A6","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0055085(transmembrane transport);GO:0015293(symporter activity);GO:0006811(ion transport);GO:0006814(sodium ion transport);GO:0030054(cell junction);GO:0045202(synapse);GO:0031410(cytoplasmic vesicle);GO:0043005(neuron projection);GO:0030672(synaptic vesicle membrane);GO:0006836(neurotransmitter transport);GO:0005313(L-glutamate transmembrane transporter activity);GO:0089711(L-glutamate transmembrane transport);GO:0098700(neurotransmitter loading into synaptic vesicle)","04724(Glutamatergic synapse);04723(Retrograde endocannabinoid signaling);04721(Synaptic vesicle cycle);05033(Nicotine addiction)","NA","NA","solute carrier family 17 member 6 [Source:HGNC Symbol;Acc:HGNC:16703]",0,0,1,0,1,1,"no","no"]
[141539,0,"chr3","-",149034989,149040259,"ENST00000472830",4,533,"ENSG00000071794","HLTF","GO:0003676(nucleic acid binding);GO:0008270(zinc ion binding);GO:0005524(ATP binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0016818(hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0061630(ubiquitin protein ligase activity);GO:0016887(ATPase activity);GO:0000209(protein polyubiquitination);GO:0006301(postreplication repair);GO:0003723(RNA binding);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0016740(transferase activity);GO:0006366(transcription from RNA polymerase II promoter);GO:0016787(hydrolase activity);GO:0006351(transcription, DNA-templated);GO:0016569(covalent chromatin modification);GO:0016567(protein ubiquitination);GO:0004386(helicase activity);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0003824(catalytic activity);GO:0008152(metabolic process);GO:0005730(nucleolus);GO:0006355(regulation of transcription, DNA-templated);GO:0031625(ubiquitin protein ligase binding);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:0001077(transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0045944(positive regulation of transcription from RNA polymerase II promoter)","NA","NA","NA","helicase like transcription factor [Source:HGNC Symbol;Acc:HGNC:11099]",0,{"v":0.011383,"d":"0.01"},"-inf","-inf",1,1,"down","no"]
[107432,0,"chr2","+",11783869,11784849,"ENST00000475286",2,192,"MSTRG.8521","LPIN1","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0016787(hydrolase activity);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0006629(lipid metabolic process);GO:0005829(cytosol);GO:0008195(phosphatidate phosphatase activity);GO:0016311(dephosphorylation);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0006631(fatty acid metabolic process);GO:0019432(triglyceride biosynthetic process);GO:0009062(fatty acid catabolic process);GO:0003674(molecular_function);GO:0005654(nucleoplasm);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0031965(nuclear membrane);GO:0007077(mitotic nuclear envelope disassembly);GO:0003713(transcription coactivator activity);GO:0005635(nuclear envelope);GO:0006656(phosphatidylcholine biosynthetic process);GO:0006646(phosphatidylethanolamine biosynthetic process);GO:0005741(mitochondrial outer membrane);GO:0006642(triglyceride mobilization);GO:0031100(animal organ regeneration);GO:0032869(cellular response to insulin stimulus)","00561(Glycerolipid metabolism);00564(Glycerophospholipid metabolism);04150(mTOR signaling pathway)","NA","NA","lipin 1 [Source:HGNC Symbol;Acc:HGNC:13345]",{"v":0.661543,"d":"0.66"},{"v":0.487397,"d":"0.49"},{"v":1.35729805476849,"d":"1.36"},{"v":0.440737562996987,"d":"0.44"},1,1,"up","no"]
[14223,0,"chr1","-",183460874,183471746,"ENST00000421703",5,2220,"MSTRG.1251","SMG7-AS1","NA","NA","NA","NA","SMG7 antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:24518]",0,0,1,0,1,1,"no","no"]
[436,0,"chr1","+",1399562,1400544,"ENST00000570344",2,515,"MSTRG.58","AL391244.1","NA","NA","NA","NA","NA",{"v":0.350003,"d":"0.35"},{"v":0.115338,"d":"0.12"},{"v":3.03458530579688,"d":"3.03"},{"v":1.60149937705837,"d":"1.60"},1,1,"up","no"]
[28672,0,"chr11","-",47167909,47176846,"ENST00000532478",9,940,"MSTRG.2366","ARFGAP2","GO:0006810(transport);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0015031(protein transport);GO:0005794(Golgi apparatus);GO:0046872(metal ion binding);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0043547(positive regulation of GTPase activity);GO:0005096(GTPase activator activity);GO:0000139(Golgi membrane);GO:0016192(vesicle-mediated transport);GO:0006890(retrograde vesicle-mediated transport, Golgi to ER);GO:0006888(ER to Golgi vesicle-mediated transport)","04144(Endocytosis)","NA","NA","ADP ribosylation factor GTPase activating protein 2 [Source:HGNC Symbol;Acc:HGNC:13504]",{"v":0.146121,"d":"0.15"},0,"inf","inf",1,1,"up","no"]
[2537,0,"chr1","-",22023997,22025483,"ENST00000635097",3,1023,"MSTRG.223","LINC01635","NA","NA","NA","NA","long intergenic non-protein coding RNA 1635 [Source:HGNC Symbol;Acc:HGNC:52422]",0,0,1,0,1,1,"no","no"]
[8449,0,"chr1","+",100538137,100542018,"ENST00000315033",2,3491,"ENSG00000181656","GPR88","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0004930(G-protein coupled receptor activity);GO:0007186(G-protein coupled receptor signaling pathway);GO:0005886(plasma membrane);GO:0004871(signal transducer activity);GO:0007165(signal transduction);GO:0003774(motor activity);GO:0005575(cellular_component);GO:0007268(chemical synaptic transmission);GO:0007631(feeding behavior);GO:0007218(neuropeptide signaling pathway);GO:0007626(locomotory behavior);GO:0019228(neuronal action potential);GO:0050885(neuromuscular process controlling balance);GO:0061743(motor learning)","NA","NA","NA","G protein-coupled receptor 88 [Source:HGNC Symbol;Acc:HGNC:4539]",{"v":0.088041,"d":"0.09"},{"v":0.081231,"d":"0.08"},{"v":1.08383498910514,"d":"1.08"},{"v":0.116145127060049,"d":"0.12"},1,1,"up","no"]
[135019,0,"chr3","-",40391850,40453180,"ENST00000452768",5,724,"ENSG00000223797","ENTPD3-AS1","NA","NA","NA","NA","ENTPD3 antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:26710]",{"v":0.050872,"d":"0.05"},0,"inf","inf",1,1,"up","no"]
[190956,0,"chr9","+",69820960,69858158,"ENST00000480564",4,550,"ENSG00000204711","C9orf135","GO:0016020(membrane);GO:0016021(integral component of membrane)","NA","NA","NA","chromosome 9 open reading frame 135 [Source:HGNC Symbol;Acc:HGNC:31422]",0,0,1,0,1,1,"no","no"]
[152988,0,"chr5","+",218311,224843,"ENST00000502379",3,679,"MSTRG.11946","SDHA","GO:0016020(membrane);GO:0005730(nucleolus);GO:0016491(oxidoreductase activity);GO:0050660(flavin adenine dinucleotide binding);GO:0055114(oxidation-reduction process);GO:0008177(succinate dehydrogenase (ubiquinone) activity);GO:0016627(oxidoreductase activity, acting on the CH-CH group of donors);GO:0006099(tricarboxylic acid cycle);GO:0006105(succinate metabolic process);GO:0022900(electron transport chain);GO:0022904(respiratory electron transport chain);GO:0005739(mitochondrion);GO:0005743(mitochondrial inner membrane);GO:0043209(myelin sheath);GO:0005515(protein binding);GO:0007399(nervous system development);GO:0006121(mitochondrial electron transport, succinate to ubiquinone);GO:0000104(succinate dehydrogenase activity);GO:0005749(mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone));GO:0009055(electron carrier activity);GO:0009061(anaerobic respiration)","00020(Citrate cycle (TCA cycle));00190(Oxidative phosphorylation);05010(Alzheimer's disease);05012(Parkinson's disease);05016(Huntington's disease);04932(Non-alcoholic fatty liver disease (NAFLD))","NA","NA","succinate dehydrogenase complex flavoprotein subunit A [Source:HGNC Symbol;Acc:HGNC:10680]",{"v":0.000131,"d":"0.00"},0,"inf","inf",1,1,"up","no"]
[119144,0,"chr2","-",218638145,218659502,"ENST00000433921",11,5800,"ENSG00000115568","ZNF142","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0003674(molecular_function);GO:0008150(biological_process);GO:0005575(cellular_component)","NA","NA","NA","zinc finger protein 142 [Source:HGNC Symbol;Acc:HGNC:12927]",{"v":0.123208,"d":"0.12"},0,"inf","inf",1,1,"up","no"]
[38766,0,"chr12","-",10118068,10130185,"ENST00000396484",4,1000,"MSTRG.3163","CLEC7A","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0043231(intracellular membrane-bounded organelle);GO:0046872(metal ion binding);GO:0005654(nucleoplasm);GO:0030246(carbohydrate binding);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0002376(immune system process);GO:0045087(innate immune response);GO:0006954(inflammatory response);GO:0002221(pattern recognition receptor signaling pathway);GO:0002223(stimulatory C-type lectin receptor signaling pathway);GO:0042110(T cell activation);GO:0008329(signaling pattern recognition receptor activity);GO:0006910(phagocytosis, recognition);GO:0008037(cell recognition);GO:0042832(defense response to protozoan);GO:0042287(MHC protein binding);GO:0009756(carbohydrate mediated signaling)","04145(Phagosome);05152(Tuberculosis)","K10074","NA","C-type lectin domain containing 7A [Source:HGNC Symbol;Acc:HGNC:14558]",{"v":0.612059,"d":"0.61"},0,"inf","inf",1,1,"up","no"]
[91536,0,"chr18","-",31129236,31162856,"ENST00000257198",16,4225,"MSTRG.7457","DSC1","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0046872(metal ion binding);GO:0005509(calcium ion binding);GO:0007155(cell adhesion);GO:0007156(homophilic cell adhesion via plasma membrane adhesion molecules);GO:0005886(plasma membrane);GO:0030054(cell junction);GO:0070062(extracellular exosome);GO:0031424(keratinization);GO:0043312(neutrophil degranulation);GO:0101003(ficolin-1-rich granule membrane);GO:0070268(cornification);GO:0001533(cornified envelope);GO:0030057(desmosome);GO:0005921(gap junction)","NA","NA","NA","desmocollin 1 [Source:HGNC Symbol;Acc:HGNC:3035]",0,0,1,0,1,1,"no","no"]
[169233,0,"chr6","+",132160765,132164491,"ENST00000447481",2,745,"ENSG00000228495","LINC01013","NA","NA","NA","NA","long intergenic non-protein coding RNA 1013 [Source:HGNC Symbol;Acc:HGNC:48987]",{"v":0.142603,"d":"0.14"},{"v":0.040506,"d":"0.04"},{"v":3.52054016688886,"d":"3.52"},{"v":1.81579680281254,"d":"1.82"},1,1,"up","no"]
[59055,0,"chr14","+",103466363,103467685,"ENST00000558611",2,687,"MSTRG.4702","MARK3","GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0000226(microtubule cytoskeleton organization);GO:0030010(establishment of cell polarity);GO:0016020(membrane);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0000165(MAPK cascade);GO:0035331(negative regulation of hippo signaling)","NA","NA","NA","microtubule affinity regulating kinase 3 [Source:HGNC Symbol;Acc:HGNC:6897]",{"v":0.246902,"d":"0.25"},{"v":1.372663,"d":"1.37"},{"v":0.179870805871507,"d":"0.18"},{"v":-2.47496704749884,"d":"-2.47"},1,1,"down","no"]
[138985,0,"chr3","+",111071743,111135954,"ENST00000485303",6,3664,"ENSG00000177707","NECTIN3","GO:0007155(cell adhesion);GO:0046982(protein heterodimerization activity);GO:0005911(cell-cell junction);GO:0042803(protein homodimerization activity);GO:0007286(spermatid development);GO:0050839(cell adhesion molecule binding);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0030054(cell junction);GO:0045202(synapse);GO:0045211(postsynaptic membrane);GO:0005887(integral component of plasma membrane);GO:0004872(receptor activity);GO:0005102(receptor binding);GO:0007156(homophilic cell adhesion via plasma membrane adhesion molecules);GO:0007157(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules);GO:0005913(cell-cell adherens junction);GO:0034332(adherens junction organization);GO:0008037(cell recognition);GO:0002089(lens morphogenesis in camera-type eye);GO:0009566(fertilization);GO:0016337(single organismal cell-cell adhesion);GO:0060042(retina morphogenesis in camera-type eye);GO:1902414(protein localization to cell junction);GO:0043296(apical junction complex);GO:0044291(cell-cell contact zone)","04514(Cell adhesion molecules (CAMs));04520(Adherens junction)","K06592","NA","nectin cell adhesion molecule 3 [Source:HGNC Symbol;Acc:HGNC:17664]",{"v":0.214988,"d":"0.21"},{"v":0.199699,"d":"0.20"},{"v":1.07656022313582,"d":"1.08"},{"v":0.106429026601477,"d":"0.11"},1,1,"up","no"]
[38522,0,"chr12","-",8534509,8540873,"ENST00000545274",5,730,"MSTRG.3113","CLEC4E","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0030246(carbohydrate binding);GO:0002376(immune system process);GO:0005886(plasma membrane);GO:0002223(stimulatory C-type lectin receptor signaling pathway);GO:0004872(receptor activity);GO:0002292(T cell differentiation involved in immune response);GO:0006955(immune response);GO:0038094(Fc-gamma receptor signaling pathway);GO:0042742(defense response to bacterium);GO:0045087(innate immune response);GO:0050715(positive regulation of cytokine secretion)","05152(Tuberculosis)","K10059","NA","C-type lectin domain family 4 member E [Source:HGNC Symbol;Acc:HGNC:14555]",{"v":0.76314,"d":"0.76"},{"v":0.569654,"d":"0.57"},{"v":1.3396552995327,"d":"1.34"},{"v":0.421861835289053,"d":"0.42"},1,1,"up","no"]
[193817,0,"chr9","+",128378067,128389869,"ENST00000483206",3,731,"MSTRG.14994","URM1","GO:0005737(cytoplasm);GO:0008033(tRNA processing);GO:0005829(cytosol);GO:0002098(tRNA wobble uridine modification);GO:0032447(protein urmylation);GO:0034227(tRNA thio-modification);GO:0016783(sulfurtransferase activity);GO:0005515(protein binding);GO:0070062(extracellular exosome);GO:0006400(tRNA modification)","04122(Sulfur relay system)","NA","NA","ubiquitin related modifier 1 [Source:HGNC Symbol;Acc:HGNC:28378]",{"v":0.220117,"d":"0.22"},{"v":0.199998,"d":"0.20"},{"v":1.10059600596006,"d":"1.10"},{"v":0.138284998279212,"d":"0.14"},1,1,"up","no"]
[119412,0,"chr2","+",219245896,219247534,"ENST00000486813",3,444,"MSTRG.9450","STK16","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0005829(cytosol);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0006366(transcription from RNA polymerase II promoter);GO:0018108(peptidyl-tyrosine phosphorylation);GO:0005515(protein binding);GO:0004715(non-membrane spanning protein tyrosine kinase activity);GO:0048471(perinuclear region of cytoplasm);GO:0001077(transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0046777(protein autophosphorylation);GO:0071560(cellular response to transforming growth factor beta stimulus);GO:0005798(Golgi-associated vesicle)","NA","NA","NA","serine/threonine kinase 16 [Source:HGNC Symbol;Acc:HGNC:11394]",{"v":0.399137,"d":"0.40"},{"v":0.2899,"d":"0.29"},{"v":1.37680924456709,"d":"1.38"},{"v":0.461328689479658,"d":"0.46"},1,1,"up","no"]
[26145,0,"chr11","-",6617370,6619396,"ENST00000530040",4,551,"MSTRG.2214","TPP1","GO:0046872(metal ion binding);GO:0016787(hydrolase activity);GO:0005515(protein binding);GO:0008233(peptidase activity);GO:0006508(proteolysis);GO:0004252(serine-type endopeptidase activity);GO:0042470(melanosome);GO:0008236(serine-type peptidase activity);GO:0007399(nervous system development);GO:0005764(lysosome);GO:0045453(bone resorption);GO:0070062(extracellular exosome);GO:0030855(epithelial cell differentiation);GO:0043202(lysosomal lumen);GO:0006629(lipid metabolic process);GO:0007417(central nervous system development);GO:0036498(IRE1-mediated unfolded protein response);GO:0004175(endopeptidase activity);GO:0008240(tripeptidyl-peptidase activity);GO:0042277(peptide binding);GO:0007040(lysosome organization);GO:0030163(protein catabolic process);GO:0043171(peptide catabolic process);GO:0050885(neuromuscular process controlling balance);GO:0005739(mitochondrion)","04142(Lysosome)","NA","NA","tripeptidyl peptidase 1 [Source:HGNC Symbol;Acc:HGNC:2073]",{"v":0.036445,"d":"0.04"},{"v":4.3E-3,"d":"0.00"},{"v":8.47558139534884,"d":"8.48"},{"v":3.08331233549587,"d":"3.08"},1,1,"up","no"]
[148753,0,"chr4","-",82897856,82900569,"ENST00000505028",3,552,"MSTRG.11700","THAP9-AS1","NA","NA","NA","NA","THAP9 antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:44172]",{"v":0.207029,"d":"0.21"},{"v":0.072916,"d":"0.07"},{"v":2.83928081628175,"d":"2.84"},{"v":1.50552554445569,"d":"1.51"},1,1,"up","no"]
[90031,0,"chr17","+",82939401,82942702,"ENST00000572794",2,1380,"ENSG00000141556","TBCD","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005886(plasma membrane);GO:0043547(positive regulation of GTPase activity);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0005096(GTPase activator activity);GO:0030054(cell junction);GO:0005813(centrosome);GO:0005815(microtubule organizing center);GO:0005923(bicellular tight junction);GO:0005912(adherens junction);GO:0006457(protein folding);GO:0048487(beta-tubulin binding);GO:0007021(tubulin complex assembly);GO:0007023(post-chaperonin tubulin folding pathway);GO:0016328(lateral plasma membrane);GO:0000278(mitotic cell cycle);GO:0070830(bicellular tight junction assembly);GO:0034333(adherens junction assembly);GO:0051087(chaperone binding);GO:0031115(negative regulation of microtubule polymerization);GO:0010812(negative regulation of cell-substrate adhesion);GO:0005874(microtubule);GO:0048667(cell morphogenesis involved in neuron differentiation)","NA","NA","NA","tubulin folding cofactor D [Source:HGNC Symbol;Acc:HGNC:11581]",{"v":0.118869,"d":"0.12"},{"v":0.231172,"d":"0.23"},{"v":0.514201546900144,"d":"0.51"},{"v":-0.959594144572252,"d":"-0.96"},1,1,"down","no"]
[105837,0,"chr19","+",55284166,55312533,"ENST00000309383",19,3079,"ENSG00000160469","BRSK1","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0005654(nucleoplasm);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0030054(cell junction);GO:0005856(cytoskeleton);GO:0006974(cellular response to DNA damage stimulus);GO:0007049(cell cycle);GO:0000287(magnesium ion binding);GO:0045202(synapse);GO:0007399(nervous system development);GO:0005813(centrosome);GO:0005815(microtubule organizing center);GO:0035556(intracellular signal transduction);GO:0007409(axonogenesis);GO:0009411(response to UV);GO:0030182(neuron differentiation);GO:0008021(synaptic vesicle);GO:0031572(G2 DNA damage checkpoint);GO:0007269(neurotransmitter secretion);GO:0030010(establishment of cell polarity);GO:0051298(centrosome duplication);GO:0043015(gamma-tubulin binding);GO:0050321(tau-protein kinase activity);GO:0019901(protein kinase binding);GO:0048812(neuron projection morphogenesis)","NA","NA","NA","BR serine/threonine kinase 1 [Source:HGNC Symbol;Acc:HGNC:18994]",{"v":0.175444,"d":"0.18"},{"v":0.222629,"d":"0.22"},{"v":0.788055464472283,"d":"0.79"},{"v":-0.343630922689035,"d":"-0.34"},1,1,"down","no"]
[135324,0,"chr3","+",43690113,43702584,"ENST00000456453",4,876,"MSTRG.10859","ABHD5","GO:0006508(proteolysis);GO:0008233(peptidase activity);GO:0005737(cytoplasm);GO:0016740(transferase activity);GO:0016787(hydrolase activity);GO:0016746(transferase activity, transferring acyl groups);GO:0006629(lipid metabolic process);GO:0005829(cytosol);GO:0006631(fatty acid metabolic process);GO:0008654(phospholipid biosynthetic process);GO:0030154(cell differentiation);GO:0003841(1-acylglycerol-3-phosphate O-acyltransferase activity);GO:0010891(negative regulation of sequestering of triglyceride);GO:0010898(positive regulation of triglyceride catabolic process);GO:0050996(positive regulation of lipid catabolic process);GO:0051006(positive regulation of lipoprotein lipase activity);GO:0005811(lipid particle);GO:0006654(phosphatidic acid biosynthetic process);GO:0042171(lysophosphatidic acid acyltransferase activity)","04923(Regulation of lipolysis in adipocyte)","NA","NA","abhydrolase domain containing 5 [Source:HGNC Symbol;Acc:HGNC:21396]",0,0,1,0,1,1,"no","no"]
[174093,0,"chr7","+",53862233,53863339,"ENST00000456660",1,1107,"ENSG00000235454","HAUS6P3","NA","NA","NA","NA","HAUS augmin like complex subunit 6 pseudogene 3 [Source:HGNC Symbol;Acc:HGNC:50772]",{"v":0.047985,"d":"0.05"},{"v":0.045059,"d":"0.05"},{"v":1.06493708249184,"d":"1.06"},{"v":0.0907681971568776,"d":"0.09"},1,1,"up","no"]
[108557,0,"chr2","+",32165841,32224112,"ENST00000435660",13,4776,"ENSG00000152683","SLC30A6","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0055085(transmembrane transport);GO:0098655(cation transmembrane transport);GO:0006812(cation transport);GO:0008324(cation transmembrane transporter activity);GO:0006810(transport);GO:0005794(Golgi apparatus);GO:0006811(ion transport);GO:0071577(zinc II ion transmembrane transport);GO:0005385(zinc ion transmembrane transporter activity);GO:0000139(Golgi membrane);GO:0006829(zinc II ion transport);GO:0010043(response to zinc ion);GO:0061088(regulation of sequestering of zinc ion)","NA","NA","NA","solute carrier family 30 member 6 [Source:HGNC Symbol;Acc:HGNC:19305]",{"v":0.082695,"d":"0.08"},0,"inf","inf",1,1,"up","no"]
[165697,0,"chr6","+",37005658,37012033,"ENST00000459781",4,866,"MSTRG.13002","FGD2","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0046872(metal ion binding);GO:0005794(Golgi apparatus);GO:0005886(plasma membrane);GO:0005089(Rho guanyl-nucleotide exchange factor activity);GO:0035023(regulation of Rho protein signal transduction);GO:0043547(positive regulation of GTPase activity);GO:0005856(cytoskeleton);GO:0042995(cell projection);GO:0005515(protein binding);GO:0005085(guanyl-nucleotide exchange factor activity);GO:0005768(endosome);GO:0005829(cytosol);GO:0030027(lamellipodium);GO:0051056(regulation of small GTPase mediated signal transduction);GO:0032587(ruffle membrane);GO:0005769(early endosome);GO:0007010(cytoskeleton organization);GO:0031901(early endosome membrane);GO:0008360(regulation of cell shape);GO:0001726(ruffle);GO:0030036(actin cytoskeleton organization);GO:0043087(regulation of GTPase activity);GO:0043065(positive regulation of apoptotic process);GO:0046847(filopodium assembly);GO:0031267(small GTPase binding);GO:1901981(phosphatidylinositol phosphate binding);GO:0043507(positive regulation of JUN kinase activity)","NA","NA","NA","FYVE, RhoGEF and PH domain containing 2 [Source:HGNC Symbol;Acc:HGNC:3664]",{"v":0.464922,"d":"0.46"},{"v":0.804898,"d":"0.80"},{"v":0.577616045759835,"d":"0.58"},{"v":-0.791817275071202,"d":"-0.79"},1,1,"down","no"]
[111213,0,"chr2","-",74377432,74391843,"ENST00000417090",5,556,"MSTRG.8832","DCTN1","GO:0006810(transport);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005829(cytosol);GO:0051301(cell division);GO:0005813(centrosome);GO:0015629(actin cytoskeleton);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0007049(cell cycle);GO:0007399(nervous system development);GO:0005874(microtubule);GO:0003774(motor activity);GO:0008017(microtubule binding);GO:0000922(spindle pole);GO:0005815(microtubule organizing center);GO:0005819(spindle);GO:0000776(kinetochore);GO:0005869(dynactin complex);GO:0030286(dynein complex);GO:0005814(centriole);GO:0005938(cell cortex);GO:0042147(retrograde transport, endosome to Golgi);GO:0000086(G2/M transition of mitotic cell cycle);GO:0010389(regulation of G2/M transition of mitotic cell cycle);GO:0097711(ciliary basal body docking);GO:0070840(dynein complex binding);GO:0010970(transport along microtubule);GO:0019886(antigen processing and presentation of exogenous peptide antigen via MHC class II);GO:0006888(ER to Golgi vesicle-mediated transport);GO:0015631(tubulin binding);GO:0005635(nuclear envelope);GO:0036498(IRE1-mediated unfolded protein response);GO:0000132(establishment of mitotic spindle orientation);GO:0000278(mitotic cell cycle);GO:0099738(cell cortex region);GO:0030904(retromer complex);GO:0031116(positive regulation of microtubule polymerization);GO:0090063(positive regulation of microtubule nucleation);GO:0035371(microtubule plus-end);GO:0060236(regulation of mitotic spindle organization);GO:0051081(nuclear envelope disassembly);GO:0010457(centriole-centriole cohesion);GO:0032402(melanosome transport);GO:0034454(microtubule anchoring at centrosome);GO:1905515(non-motile cilium assembly);GO:0031252(cell leading edge);GO:0043234(protein complex)","04962(Vasopressin-regulated water reabsorption);05016(Huntington's disease)","NA","NA","dynactin subunit 1 [Source:HGNC Symbol;Acc:HGNC:2711]",0,{"v":0.128189,"d":"0.13"},"-inf","-inf",1,1,"down","no"]
[134745,0,"chr3","-",37808496,37861732,"ENST00000630010",4,575,"MSTRG.10807","ITGA9-AS1","NA","NA","NA","NA","ITGA9 antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:49668]",0,{"v":0.317608,"d":"0.32"},"-inf","-inf",1,1,"down","no"]
[101969,0,"chr19","+",41895379,41930150,"ENST00000599589",21,2636,"MSTRG.8188","ARHGEF1","GO:0003723(RNA binding);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0005089(Rho guanyl-nucleotide exchange factor activity);GO:0035023(regulation of Rho protein signal transduction);GO:0043547(positive regulation of GTPase activity);GO:0005515(protein binding);GO:0005096(GTPase activator activity);GO:0005085(guanyl-nucleotide exchange factor activity);GO:0051056(regulation of small GTPase mediated signal transduction);GO:0007266(Rho protein signal transduction);GO:0008283(cell proliferation);GO:0043065(positive regulation of apoptotic process);GO:0050771(negative regulation of axonogenesis)","04810(Regulation of actin cytoskeleton);04611(Platelet activation);04270(Vascular smooth muscle contraction);05200(Pathways in cancer);05205(Proteoglycans in cancer)","NA","NA","Rho guanine nucleotide exchange factor 1 [Source:HGNC Symbol;Acc:HGNC:681]",{"v":0.049981,"d":"0.05"},{"v":0.008502,"d":"0.01"},{"v":5.87873441543166,"d":"5.88"},{"v":2.55550560249312,"d":"2.56"},1,1,"up","no"]
[67302,0,"chr16","-",188969,229463,"ENST00000337351",9,2097,"ENSG00000007392","LUC7L","GO:0003729(mRNA binding);GO:0005515(protein binding);GO:0042802(identical protein binding);GO:0005685(U1 snRNP);GO:0006376(mRNA splice site selection);GO:0071004(U2-type prespliceosome);GO:0050733(RS domain binding);GO:0045843(negative regulation of striated muscle tissue development);GO:0005634(nucleus)","NA","NA","NA","LUC7 like [Source:HGNC Symbol;Acc:HGNC:6723]",{"v":0.347309,"d":"0.35"},{"v":0.065171,"d":"0.07"},{"v":5.32919550106642,"d":"5.33"},{"v":2.41391775920894,"d":"2.41"},1,1,"up","no"]
[39764,0,"chr12","+",25803298,25804526,"ENST00000543961",1,1229,"ENSG00000255725","TDGP1","NA","NA","NA","NA","thymine-DNA glycosylase pseudogene 1 [Source:HGNC Symbol;Acc:HGNC:49891]",{"v":0.106409,"d":"0.11"},{"v":0.031057,"d":"0.03"},{"v":3.42624851080272,"d":"3.43"},{"v":1.7766297959929,"d":"1.78"},1,1,"up","no"]
[185889,0,"chr8","-",98401403,98526926,"ENST00000517832",4,594,"ENSG00000104375","STK3","GO:0090090(negative regulation of canonical Wnt signaling pathway);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0007165(signal transduction);GO:0005515(protein binding);GO:0006915(apoptotic process);GO:0000287(magnesium ion binding);GO:0005829(cytosol);GO:0043065(positive regulation of apoptotic process);GO:0043234(protein complex);GO:0071902(positive regulation of protein serine/threonine kinase activity);GO:0042981(regulation of apoptotic process);GO:0007346(regulation of mitotic cell cycle);GO:0035556(intracellular signal transduction);GO:0035329(hippo signaling);GO:0046983(protein dimerization activity);GO:0031098(stress-activated protein kinase signaling cascade);GO:0023014(signal transduction by protein phosphorylation);GO:0043539(protein serine/threonine kinase activator activity);GO:0032092(positive regulation of protein binding);GO:0050821(protein stabilization);GO:0051091(positive regulation of sequence-specific DNA binding transcription factor activity);GO:0001841(neural tube formation);GO:0003157(endocardium development);GO:0007417(central nervous system development);GO:0008285(negative regulation of cell proliferation);GO:0045600(positive regulation of fat cell differentiation);GO:0046330(positive regulation of JNK cascade);GO:0046621(negative regulation of organ growth);GO:0051897(positive regulation of protein kinase B signaling);GO:0060215(primitive hemopoiesis);GO:0060706(cell differentiation involved in embryonic placenta development);GO:0060800(regulation of cell differentiation involved in embryonic placenta development);GO:0097284(hepatocyte apoptotic process);GO:1902043(positive regulation of extrinsic apoptotic signaling pathway via death domain receptors)","04010(MAPK signaling pathway);04390(Hippo signaling pathway);04392(Hippo signaling pathway - multiple species)","NA","NA","serine/threonine kinase 3 [Source:HGNC Symbol;Acc:HGNC:11406]",{"v":0.045931,"d":"0.05"},0,"inf","inf",1,1,"up","no"]
[21019,0,"chr10","+",70672803,70762441,"ENST00000373208",22,5269,"ENSG00000138316","ADAMTS14","GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0016787(hydrolase activity);GO:0008233(peptidase activity);GO:0006508(proteolysis);GO:0005576(extracellular region);GO:0005578(proteinaceous extracellular matrix);GO:0004222(metalloendopeptidase activity);GO:0008237(metallopeptidase activity);GO:0030574(collagen catabolic process);GO:0030199(collagen fibril organization)","NA","NA","NA","ADAM metallopeptidase with thrombospondin type 1 motif 14 [Source:HGNC Symbol;Acc:HGNC:14899]",{"v":0.020163,"d":"0.02"},{"v":0.019317,"d":"0.02"},{"v":1.04379562043796,"d":"1.04"},{"v":0.0618392538178626,"d":"0.06"},1,1,"up","no"]
[88878,0,"chr17","-",78812860,78828964,"ENST00000586066",10,960,"MSTRG.7296","USP36","GO:0003723(RNA binding);GO:0005634(nucleus);GO:0016607(nuclear speck);GO:0005730(nucleolus);GO:0016579(protein deubiquitination);GO:0016787(hydrolase activity);GO:0008233(peptidase activity);GO:0008234(cysteine-type peptidase activity);GO:0006508(proteolysis);GO:0006511(ubiquitin-dependent protein catabolic process);GO:0036459(thiol-dependent ubiquitinyl hydrolase activity);GO:1903146(regulation of mitophagy);GO:0004843(thiol-dependent ubiquitin-specific protease activity);GO:1903955(positive regulation of protein targeting to mitochondrion)","NA","NA","NA","ubiquitin specific peptidase 36 [Source:HGNC Symbol;Acc:HGNC:20062]",0,{"v":0.318145,"d":"0.32"},"-inf","-inf",1,1,"down","no"]
[85296,0,"chr17","-",49621946,49646622,"ENST00000510476",3,773,"MSTRG.7004","SPOP","GO:0005634(nucleus);GO:0016607(nuclear speck);GO:0016567(protein ubiquitination);GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0005654(nucleoplasm);GO:0030162(regulation of proteolysis);GO:0042787(protein ubiquitination involved in ubiquitin-dependent protein catabolic process);GO:0019005(SCF ubiquitin ligase complex);GO:0031625(ubiquitin protein ligase binding);GO:0043161(proteasome-mediated ubiquitin-dependent protein catabolic process);GO:0031463(Cul3-RING ubiquitin ligase complex);GO:0001085(RNA polymerase II transcription factor binding);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0042593(glucose homeostasis);GO:0043433(negative regulation of sequence-specific DNA binding transcription factor activity);GO:1902237(positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway);GO:2000676(positive regulation of type B pancreatic cell apoptotic process)","04340(Hedgehog signaling pathway)","NA","NA","speckle type BTB/POZ protein [Source:HGNC Symbol;Acc:HGNC:11254]",0,{"v":0.000558,"d":"0.00"},"-inf","-inf",1,1,"down","no"]
[64868,0,"chr15","+",75336060,75339400,"ENST00000567023",4,926,"ENSG00000140365","COMMD4","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0005515(protein binding)","NA","NA","NA","COMM domain containing 4 [Source:HGNC Symbol;Acc:HGNC:26027]",0,0,1,0,1,1,"no","no"]
[200945,0,"chrX","-",153703001,153724044,"ENST00000423827",6,669,"MSTRG.15486","BCAP31","GO:0005739(mitochondrion);GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0006886(intracellular protein transport);GO:0015031(protein transport);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005515(protein binding);GO:0006915(apoptotic process);GO:0016192(vesicle-mediated transport);GO:0005887(integral component of plasma membrane);GO:0005829(cytosol);GO:0006888(ER to Golgi vesicle-mediated transport);GO:0097194(execution phase of apoptosis);GO:2001244(positive regulation of intrinsic apoptotic signaling pathway);GO:0007204(positive regulation of cytosolic calcium ion concentration);GO:0005811(lipid particle);GO:0043280(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process);GO:0033116(endoplasmic reticulum-Golgi intermediate compartment membrane);GO:0002474(antigen processing and presentation of peptide antigen via MHC class I);GO:0071556(integral component of lumenal side of endoplasmic reticulum membrane);GO:1903071(positive regulation of ER-associated ubiquitin-dependent protein catabolic process);GO:0035584(calcium-mediated signaling using intracellular calcium source);GO:0032471(negative regulation of endoplasmic reticulum calcium ion concentration);GO:0051561(positive regulation of mitochondrial calcium ion concentration);GO:0005784(Sec61 translocon complex);GO:0070973(protein localization to endoplasmic reticulum exit site);GO:1904154(positive regulation of retrograde protein transport, ER to cytosol);GO:0097038(perinuclear endoplasmic reticulum);GO:0032403(protein complex binding);GO:0042288(MHC class I protein binding);GO:0007283(spermatogenesis);GO:0000139(Golgi membrane);GO:0030136(clathrin-coated vesicle);GO:0032580(Golgi cisterna membrane)","04141(Protein processing in endoplasmic reticulum);05165(Human papillomavirus infection)","NA","NA","B-cell receptor associated protein 31 [Source:HGNC Symbol;Acc:HGNC:16695]",{"v":0.104998,"d":"0.10"},{"v":0.111164,"d":"0.11"},{"v":0.944532402576374,"d":"0.94"},{"v":-0.0823278051721834,"d":"-0.08"},1,1,"down","no"]
[178587,0,"chr7","+",128866308,128872044,"ENST00000609480",2,3902,"MSTRG.13958","AC025594.2","NA","NA","NA","NA","NA",{"v":0.14342,"d":"0.14"},{"v":0.070956,"d":"0.07"},{"v":2.02125260724956,"d":"2.02"},{"v":1.01524963465804,"d":"1.02"},1,1,"up","no"]
[123257,0,"chr20","+",35542443,35556262,"ENST00000496172",8,781,"MSTRG.9699","ERGIC3","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005794(Golgi apparatus);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0016192(vesicle-mediated transport);GO:0033116(endoplasmic reticulum-Golgi intermediate compartment membrane)","NA","NA","NA","ERGIC and golgi 3 [Source:HGNC Symbol;Acc:HGNC:15927]",{"v":0.106087,"d":"0.11"},{"v":0.094263,"d":"0.09"},{"v":1.12543627934608,"d":"1.13"},{"v":0.17048437569583,"d":"0.17"},1,1,"up","no"]
[38774,0,"chr12","-",10127446,10130257,"ENST00000525605",3,573,"MSTRG.3163","CLEC7A","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0043231(intracellular membrane-bounded organelle);GO:0046872(metal ion binding);GO:0005654(nucleoplasm);GO:0030246(carbohydrate binding);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0002376(immune system process);GO:0045087(innate immune response);GO:0006954(inflammatory response);GO:0002221(pattern recognition receptor signaling pathway);GO:0002223(stimulatory C-type lectin receptor signaling pathway);GO:0042110(T cell activation);GO:0008329(signaling pattern recognition receptor activity);GO:0006910(phagocytosis, recognition);GO:0008037(cell recognition);GO:0042832(defense response to protozoan);GO:0042287(MHC protein binding);GO:0009756(carbohydrate mediated signaling)","04145(Phagosome);05152(Tuberculosis)","NA","NA","C-type lectin domain containing 7A [Source:HGNC Symbol;Acc:HGNC:14558]",{"v":0.538674,"d":"0.54"},{"v":0.505897,"d":"0.51"},{"v":1.06478986829335,"d":"1.06"},{"v":0.0905687488713793,"d":"0.09"},1,1,"up","no"]
[9301,0,"chr1","+",112674698,112700734,"ENST00000369644",22,4100,"MSTRG.811","MOV10","GO:0003723(RNA binding);GO:0005737(cytoplasm);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0005829(cytosol);GO:0016787(hydrolase activity);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0004386(helicase activity);GO:0005515(protein binding);GO:0005615(extracellular space);GO:0031047(gene silencing by RNA);GO:0000932(P-body);GO:0038111(interleukin-7-mediated signaling pathway);GO:0048015(phosphatidylinositol-mediated signaling);GO:0045652(regulation of megakaryocyte differentiation);GO:0007223(Wnt signaling pathway, calcium modulating pathway);GO:0035195(gene silencing by miRNA);GO:0035279(mRNA cleavage involved in gene silencing by miRNA)","NA","NA","NA","Mov10 RISC complex RNA helicase [Source:HGNC Symbol;Acc:HGNC:7200]",0,{"v":0.024643,"d":"0.02"},"-inf","-inf",1,1,"down","no"]
[169716,0,"chr6","-",139239083,139270561,"ENST00000621913",7,959,"MSTRG.13313","AL158850.2","NA","NA","NA","NA","NA",{"v":0.058029,"d":"0.06"},0,"inf","inf",1,1,"up","no"]
[138741,0,"chr3","+",101827993,101861022,"ENST00000394054",13,3787,"MSTRG.11097","NFKBIZ","GO:0016607(nuclear speck);GO:0000932(P-body);GO:0005634(nucleus);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0005515(protein binding);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0003712(transcription cofactor activity);GO:0006954(inflammatory response)","05202(Transcriptional misregulation in cancers)","K14242","NA","NFKB inhibitor zeta [Source:HGNC Symbol;Acc:HGNC:29805]",{"v":0.011278,"d":"0.01"},0,"inf","inf",1,1,"up","no"]
[103478,0,"chr19","-",48306300,48321894,"ENST00000504608",5,462,"MSTRG.8276","CCDC114","GO:0042995(cell projection);GO:0005515(protein binding);GO:0005929(cilium);GO:0036158(outer dynein arm assembly);GO:0003341(cilium movement);GO:0005930(axoneme);GO:0036157(outer dynein arm)","NA","NA","NA","coiled-coil domain containing 114 [Source:HGNC Symbol;Acc:HGNC:26560]",{"v":0.050636,"d":"0.05"},0,"inf","inf",1,1,"up","no"]
[178707,0,"chr7","+",130207860,130216843,"ENST00000297819",3,1159,"ENSG00000165120","SSMEM1","GO:0016020(membrane);GO:0016021(integral component of membrane)","NA","NA","NA","serine rich single-pass membrane protein 1 [Source:HGNC Symbol;Acc:HGNC:29580]",0,0,1,0,1,1,"no","no"]
[129917,0,"chr22","-",28687897,28734721,"ENST00000402731",13,1545,"ENSG00000183765","CHEK2","GO:0004672(protein kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0005794(Golgi apparatus);GO:0005654(nucleoplasm);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0004674(protein serine/threonine kinase activity);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0051301(cell division);GO:0042803(protein homodimerization activity);GO:0005515(protein binding);GO:0006281(DNA repair);GO:0006974(cellular response to DNA damage stimulus);GO:0007049(cell cycle);GO:0006915(apoptotic process);GO:0045893(positive regulation of transcription, DNA-templated);GO:0042802(identical protein binding);GO:0006977(DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest);GO:0019901(protein kinase binding);GO:0050821(protein stabilization);GO:0044257(cellular protein catabolic process);GO:0031625(ubiquitin protein ligase binding);GO:0090307(mitotic spindle assembly);GO:0018105(peptidyl-serine phosphorylation);GO:1901796(regulation of signal transduction by p53 class mediator);GO:0042981(regulation of apoptotic process);GO:0016605(PML body);GO:0046777(protein autophosphorylation);GO:0090399(replicative senescence);GO:0000781(chromosome, telomeric region);GO:0000077(DNA damage checkpoint);GO:0006975(DNA damage induced protein phosphorylation);GO:0018107(peptidyl-threonine phosphorylation);GO:0000086(G2/M transition of mitotic cell cycle);GO:0006302(double-strand break repair);GO:0001302(replicative cell aging);GO:0008630(intrinsic apoptotic signaling pathway in response to DNA damage);GO:0042176(regulation of protein catabolic process);GO:0042770(signal transduction in response to DNA damage);GO:0072428(signal transduction involved in intra-S DNA damage checkpoint);GO:0001934(positive regulation of protein phosphorylation);GO:0006978(DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator);GO:0010332(response to gamma radiation);GO:0035690(cellular response to drug);GO:0042771(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator);GO:0071157(negative regulation of cell cycle arrest);GO:0071480(cellular response to gamma radiation);GO:1903416(response to glycoside);GO:1903926(cellular response to bisphenol A);GO:2000002(negative regulation of DNA damage checkpoint);GO:2000210(positive regulation of anoikis)","04110(Cell cycle);04115(p53 signaling pathway);04218(Cellular senescence);05166(HTLV-I infection)","NA","NA","checkpoint kinase 2 [Source:HGNC Symbol;Acc:HGNC:16627]",0,{"v":0.051253,"d":"0.05"},"-inf","-inf",1,1,"down","no"]
[48778,0,"chr12","+",133038875,133048844,"ENST00000543310",4,562,"ENSG00000198040","ZNF84","GO:0003676(nucleic acid binding);GO:0046872(metal ion binding);GO:0006355(regulation of transcription, DNA-templated);GO:0005622(intracellular);GO:0005634(nucleus);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0008270(zinc ion binding);GO:0001570(vasculogenesis);GO:0001822(kidney development);GO:0006807(nitrogen compound metabolic process);GO:0009791(post-embryonic development);GO:0014909(smooth muscle cell migration);GO:0030097(hemopoiesis);GO:0035264(multicellular organism growth);GO:0048008(platelet-derived growth factor receptor signaling pathway);GO:0048705(skeletal system morphogenesis);GO:0048745(smooth muscle tissue development);GO:0060021(palate development);GO:0060325(face morphogenesis)","NA","NA","NA","zinc finger protein 84 [Source:HGNC Symbol;Acc:HGNC:13159]",0,0,1,0,1,1,"no","no"]
[76732,0,"chr16","-",88656170,88658783,"ENST00000566636",3,863,"MSTRG.6227","MVD","GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0016829(lyase activity);GO:0006629(lipid metabolic process);GO:0005829(cytosol);GO:0042803(protein homodimerization activity);GO:0006694(steroid biosynthetic process);GO:0008202(steroid metabolic process);GO:0008299(isoprenoid biosynthetic process);GO:0016126(sterol biosynthetic process);GO:0008203(cholesterol metabolic process);GO:0016831(carboxy-lyase activity);GO:0006695(cholesterol biosynthetic process);GO:0008284(positive regulation of cell proliferation);GO:0045540(regulation of cholesterol biosynthetic process);GO:0030544(Hsp70 protein binding);GO:0004163(diphosphomevalonate decarboxylase activity);GO:0006489(dolichyl diphosphate biosynthetic process);GO:0019287(isopentenyl diphosphate biosynthetic process, mevalonate pathway)","00900(Terpenoid backbone biosynthesis)","NA","NA","mevalonate diphosphate decarboxylase [Source:HGNC Symbol;Acc:HGNC:7529]",{"v":0.000689,"d":"0.00"},0,"inf","inf",1,1,"up","no"]
[121025,0,"chr2","+",241150496,241167174,"ENST00000401987",8,820,"MSTRG.9523","PPP1R7","GO:0005634(nucleus);GO:0050790(regulation of catalytic activity);GO:0005515(protein binding);GO:0008150(biological_process);GO:0070062(extracellular exosome);GO:0005737(cytoplasm);GO:0019888(protein phosphatase regulator activity);GO:0030234(enzyme regulator activity);GO:0035307(positive regulation of protein dephosphorylation);GO:0005694(chromosome);GO:0007059(chromosome segregation);GO:0061588(calcium activated phospholipid scrambling)","NA","NA","NA","protein phosphatase 1 regulatory subunit 7 [Source:HGNC Symbol;Acc:HGNC:9295]",{"v":0.128321,"d":"0.13"},{"v":0.34761,"d":"0.35"},{"v":0.369152210810966,"d":"0.37"},{"v":-1.43771229620633,"d":"-1.44"},1,1,"down","no"]
[69645,0,"chr16","-",11402131,11414555,"ENST00000596416",4,518,"ENSG00000188897","AC099489.1","GO:0006869(lipid transport);GO:0005319(lipid transporter activity)","NA","NA","NA","NA",{"v":0.240349,"d":"0.24"},{"v":0.340779,"d":"0.34"},{"v":0.705292873093706,"d":"0.71"},{"v":-0.503705633375068,"d":"-0.50"},1,1,"down","no"]
[96992,0,"chr19","-",12319179,12333492,"ENST00000594577",5,749,"ENSG00000188868","ZNF563","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0005622(intracellular)","NA","NA","NA","zinc finger protein 563 [Source:HGNC Symbol;Acc:HGNC:30498]",0,0,1,0,1,1,"no","no"]
[53115,0,"chr14","-",22998773,23010143,"ENST00000553958",3,588,"ENSG00000100802","C14orf93","GO:0003723(RNA binding);GO:0005515(protein binding);GO:0005576(extracellular region)","NA","NA","NA","chromosome 14 open reading frame 93 [Source:HGNC Symbol;Acc:HGNC:20162]",0,{"v":0.084545,"d":"0.08"},"-inf","-inf",1,1,"down","no"]
[131561,0,"chr22","+",40346530,40361577,"ENST00000623287",7,856,"MSTRG.10502","ADSL","GO:0003824(catalytic activity);GO:0016829(lyase activity);GO:0006164(purine nucleotide biosynthetic process);GO:0044208('de novo' AMP biosynthetic process);GO:0004018(N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity);GO:0070626((S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido)succinate AMP-lyase (fumarate-forming) activity);GO:0006189('de novo' IMP biosynthetic process);GO:0009152(purine ribonucleotide biosynthetic process);GO:0005829(cytosol);GO:0009168(purine ribonucleoside monophosphate biosynthetic process);GO:0051262(protein tetramerization);GO:0006167(AMP biosynthetic process);GO:0001666(response to hypoxia);GO:0006163(purine nucleotide metabolic process);GO:0007584(response to nutrient);GO:0009060(aerobic respiration);GO:0009156(ribonucleoside monophosphate biosynthetic process);GO:0014850(response to muscle activity);GO:0042594(response to starvation);GO:0005739(mitochondrion)","00230(Purine metabolism);00250(Alanine, aspartate and glutamate metabolism)","NA","NA","adenylosuccinate lyase [Source:HGNC Symbol;Acc:HGNC:291]",{"v":0.346365,"d":"0.35"},0,"inf","inf",1,1,"up","no"]
[23132,0,"chr10","-",102480795,102484374,"ENST00000494549",4,520,"MSTRG.1934","ACTR1A","GO:0005869(dynactin complex);GO:0005737(cytoplasm);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0015630(microtubule cytoskeleton);GO:0005856(cytoskeleton);GO:0005813(centrosome);GO:0005815(microtubule organizing center);GO:0005515(protein binding);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0005938(cell cortex);GO:0000086(G2/M transition of mitotic cell cycle);GO:0010389(regulation of G2/M transition of mitotic cell cycle);GO:0097711(ciliary basal body docking);GO:0019886(antigen processing and presentation of exogenous peptide antigen via MHC class II);GO:0016192(vesicle-mediated transport);GO:0006888(ER to Golgi vesicle-mediated transport);GO:0005875(microtubule associated complex);GO:0099738(cell cortex region);GO:0007283(spermatogenesis);GO:0002177(manchette);GO:0005814(centriole);GO:0030137(COPI-coated vesicle);GO:0043209(myelin sheath)","NA","NA","NA","ARP1 actin related protein 1 homolog A [Source:HGNC Symbol;Acc:HGNC:167]",0,{"v":0.246555,"d":"0.25"},"-inf","-inf",1,1,"down","no"]
[183501,0,"chr8","+",42697419,42737407,"ENST00000289957",6,2294,"ENSG00000147432","CHRNB3","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005216(ion channel activity);GO:0006811(ion transport);GO:0005886(plasma membrane);GO:0030054(cell junction);GO:0045202(synapse);GO:0045211(postsynaptic membrane);GO:0005230(extracellular ligand-gated ion channel activity);GO:0060079(excitatory postsynaptic potential);GO:0060078(regulation of postsynaptic membrane potential);GO:0022848(acetylcholine-gated cation-selective channel activity);GO:0007165(signal transduction);GO:0015267(channel activity);GO:0007274(neuromuscular synaptic transmission);GO:0042166(acetylcholine binding);GO:0015276(ligand-gated ion channel activity);GO:0035094(response to nicotine);GO:0005892(acetylcholine-gated channel complex);GO:0098655(cation transmembrane transport);GO:0007271(synaptic transmission, cholinergic);GO:0008144(drug binding);GO:0051291(protein heterooligomerization);GO:0043005(neuron projection)","04080(Neuroactive ligand-receptor interaction)","K04814","NA","cholinergic receptor nicotinic beta 3 subunit [Source:HGNC Symbol;Acc:HGNC:1963]",0,{"v":1.469E-3,"d":"0.00"},"-inf","-inf",1,1,"down","no"]
[140487,0,"chr3","+",130560334,130678155,"ENST00000358511",36,9581,"ENSG00000206384","COL6A6","GO:0007155(cell adhesion);GO:0005576(extracellular region);GO:0005581(collagen trimer);GO:0005578(proteinaceous extracellular matrix);GO:0030574(collagen catabolic process)","04151(PI3K-Akt signaling pathway);04512(ECM-receptor interaction);04510(Focal adhesion);04974(Protein digestion and absorption);05165(Human papillomavirus infection)","K06238","NA","collagen type VI alpha 6 chain [Source:HGNC Symbol;Acc:HGNC:27023]",{"v":0.004055,"d":"0.00"},0,"inf","inf",1,1,"up","no"]
[84074,0,"chr17","+",44115912,44120595,"ENST00000585899",3,359,"MSTRG.6885","AC023855.1","NA","NA","NA","NA","NA",0,{"v":0.050696,"d":"0.05"},"-inf","-inf",1,1,"down","no"]
[92089,0,"chr18","-",45857822,45916454,"ENST00000590884",23,3767,"ENSG00000152223","EPG5","GO:0006914(autophagy);GO:0005737(cytoplasm);GO:0097352(autophagosome maturation);GO:0032456(endocytic recycling)","NA","NA","NA","ectopic P-granules autophagy protein 5 homolog [Source:HGNC Symbol;Acc:HGNC:29331]",{"v":0.040679,"d":"0.04"},0,"inf","inf",1,1,"up","no"]
[129015,0,"chr22","-",21491976,21514223,"ENST00000491562",2,209,"ENSG00000183506","PI4KAP2","NA","NA","NA","NA","phosphatidylinositol 4-kinase alpha pseudogene 2 [Source:HGNC Symbol;Acc:HGNC:33577]",0,{"v":0.103609,"d":"0.10"},"-inf","-inf",1,1,"down","no"]
[10929,0,"chr1","-",151612038,151613363,"ENST00000504583",2,535,"MSTRG.957","AL391335.1","NA","NA","NA","NA","NA",{"v":0.257769,"d":"0.26"},0,"inf","inf",1,1,"up","no"]
[66585,0,"chr15","-",90981963,90994500,"ENST00000559811",4,414,"ENSG00000198901","PRC1","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005654(nucleoplasm);GO:0051301(cell division);GO:0005886(plasma membrane);GO:0015630(microtubule cytoskeleton);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0007049(cell cycle);GO:0008017(microtubule binding);GO:0001578(microtubule bundle formation);GO:0005874(microtubule);GO:0000226(microtubule cytoskeleton organization);GO:0000922(spindle pole);GO:0005819(spindle);GO:0030496(midbody);GO:0000910(cytokinesis);GO:0005829(cytosol);GO:0019901(protein kinase binding);GO:0008284(positive regulation of cell proliferation);GO:0019894(kinesin binding);GO:0000022(mitotic spindle elongation);GO:0005876(spindle microtubule);GO:0070938(contractile ring)","NA","NA","NA","protein regulator of cytokinesis 1 [Source:HGNC Symbol;Acc:HGNC:9341]",0,0,1,0,1,1,"no","no"]
[160141,0,"chr5","-",151029949,151087158,"ENST00000315050",18,2785,"MSTRG.12464","TNIP1","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0005515(protein binding);GO:0002755(MyD88-dependent toll-like receptor signaling pathway);GO:0006954(inflammatory response);GO:0042802(identical protein binding);GO:0050727(regulation of inflammatory response);GO:0043124(negative regulation of I-kappaB kinase/NF-kappaB signaling);GO:0070373(negative regulation of ERK1 and ERK2 cascade);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0005622(intracellular);GO:0016579(protein deubiquitination);GO:0045071(negative regulation of viral genome replication);GO:0050729(positive regulation of inflammatory response);GO:0006412(translation);GO:0006952(defense response);GO:0051019(mitogen-activated protein kinase binding);GO:0009101(glycoprotein biosynthetic process);GO:0007159(leukocyte cell-cell adhesion);GO:0031593(polyubiquitin binding);GO:0071222(cellular response to lipopolysaccharide);GO:0085032(modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade);GO:1903003(positive regulation of protein deubiquitination)","NA","NA","NA","TNFAIP3 interacting protein 1 [Source:HGNC Symbol;Acc:HGNC:16903]",{"v":0.035069,"d":"0.04"},{"v":0.257584,"d":"0.26"},{"v":0.136145878626002,"d":"0.14"},{"v":-2.87677478474821,"d":"-2.88"},1,1,"down","no"]
[42251,0,"chr12","+",53501332,53503472,"ENST00000547388",2,576,"MSTRG.3417","TARBP2","GO:0003723(RNA binding);GO:0003725(double-stranded RNA binding);GO:0016442(RISC complex);GO:0030422(production of siRNA involved in RNA interference);GO:0035197(siRNA binding);GO:0031054(pre-miRNA processing);GO:0035280(miRNA loading onto RISC involved in gene silencing by miRNA);GO:0046782(regulation of viral transcription);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005654(nucleoplasm);GO:0042803(protein homodimerization activity);GO:0005515(protein binding);GO:0016604(nuclear body);GO:0048471(perinuclear region of cytoplasm);GO:0031047(gene silencing by RNA);GO:0042802(identical protein binding);GO:0005829(cytosol);GO:0006417(regulation of translation);GO:0035087(siRNA loading onto RISC involved in RNA interference);GO:0019899(enzyme binding);GO:0006469(negative regulation of protein kinase activity);GO:0047485(protein N-terminus binding);GO:0045070(positive regulation of viral genome replication);GO:0070883(pre-miRNA binding);GO:0010586(miRNA metabolic process);GO:0035196(production of miRNAs involved in gene silencing by miRNA);GO:0070578(RISC-loading complex);GO:0036002(pre-mRNA binding);GO:0007286(spermatid development);GO:0007338(single fertilization);GO:0030423(targeting of mRNA for destruction involved in RNA interference);GO:0035264(multicellular organism growth);GO:0045727(positive regulation of translation);GO:0050689(negative regulation of defense response to virus by host);GO:0035068(micro-ribonucleoprotein complex)","NA","NA","NA","TARBP2, RISC loading complex RNA binding subunit [Source:HGNC Symbol;Acc:HGNC:11569]",0,0,1,0,1,1,"no","no"]
[20673,0,"chr10","-",63219877,63521850,"ENST00000633035",4,499,"MSTRG.1732","JMJD1C","GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0016569(covalent chromatin modification);GO:0005515(protein binding);GO:0051213(dioxygenase activity);GO:0005654(nucleoplasm);GO:0005622(intracellular);GO:0000976(transcription regulatory region sequence-specific DNA binding);GO:0007596(blood coagulation);GO:0000785(chromatin);GO:0031490(chromatin DNA binding);GO:0032454(histone demethylase activity (H3-K9 specific));GO:0033169(histone H3-K9 demethylation);GO:0046966(thyroid hormone receptor binding)","05202(Transcriptional misregulation in cancers)","NA","NA","jumonji domain containing 1C [Source:HGNC Symbol;Acc:HGNC:12313]",{"v":0.476368,"d":"0.48"},{"v":0.131604,"d":"0.13"},{"v":3.6197076076715,"d":"3.62"},{"v":1.85587316415952,"d":"1.86"},1,1,"up","no"]
[117003,0,"chr2","+",181457202,181459391,"ENST00000476089",2,1846,"MSTRG.9287","ITGA4","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0046872(metal ion binding);GO:0007155(cell adhesion);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0007229(integrin-mediated signaling pathway);GO:0008305(integrin complex);GO:0005925(focal adhesion);GO:0050776(regulation of immune response);GO:0050900(leukocyte migration);GO:0070062(extracellular exosome);GO:0009986(cell surface);GO:0030198(extracellular matrix organization);GO:0043113(receptor clustering);GO:0007160(cell-matrix adhesion);GO:0015026(coreceptor activity);GO:0050839(cell adhesion molecule binding);GO:0034446(substrate adhesion-dependent cell spreading);GO:0035987(endodermal cell differentiation);GO:0019960(C-X3-C chemokine binding);GO:0034113(heterotypic cell-cell adhesion);GO:0007159(leukocyte cell-cell adhesion);GO:0030183(B cell differentiation);GO:0050901(leukocyte tethering or rolling);GO:0003366(cell-matrix adhesion involved in ameboidal cell migration);GO:0090074(negative regulation of protein homodimerization activity);GO:0034669(integrin alpha4-beta7 complex);GO:0001968(fibronectin binding);GO:0003823(antigen binding);GO:1990405(protein antigen binding);GO:0002687(positive regulation of leukocyte migration);GO:0050904(diapedesis);GO:0071345(cellular response to cytokine stimulus);GO:0098657(import into cell);GO:1903039(positive regulation of leukocyte cell-cell adhesion);GO:1903238(positive regulation of leukocyte tethering or rolling);GO:1990771(clathrin-dependent extracellular exosome endocytosis);GO:2000406(positive regulation of T cell migration)","04151(PI3K-Akt signaling pathway);04512(ECM-receptor interaction);04514(Cell adhesion molecules (CAMs));04510(Focal adhesion);04810(Regulation of actin cytoskeleton);04640(Hematopoietic cell lineage);04670(Leukocyte transendothelial migration);04672(Intestinal immune network for IgA production);05410(Hypertrophic cardiomyopathy (HCM));05412(Arrhythmogenic right ventricular cardiomyopathy (ARVC));05414(Dilated cardiomyopathy (DCM));05165(Human papillomavirus infection);05140(Leishmaniasis)","NA","NA","integrin subunit alpha 4 [Source:HGNC Symbol;Acc:HGNC:6140]",{"v":0.112366,"d":"0.11"},{"v":0.23846,"d":"0.24"},{"v":0.471215298163214,"d":"0.47"},{"v":-1.08554171737872,"d":"-1.09"},1,1,"down","no"]
[30985,0,"chr11","-",65045313,65047886,"ENST00000532802",4,566,"ENSG00000168060","NAALADL1","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0046872(metal ion binding);GO:0016787(hydrolase activity);GO:0005886(plasma membrane);GO:0003824(catalytic activity);GO:0008152(metabolic process);GO:0008233(peptidase activity);GO:0006508(proteolysis);GO:0004180(carboxypeptidase activity);GO:0008237(metallopeptidase activity);GO:0016805(dipeptidase activity);GO:0016324(apical plasma membrane)","NA","NA","NA","N-acetylated alpha-linked acidic dipeptidase like 1 [Source:HGNC Symbol;Acc:HGNC:23536]",{"v":0.15196,"d":"0.15"},{"v":0.425187,"d":"0.43"},{"v":0.357395687074158,"d":"0.36"},{"v":-1.48440587034083,"d":"-1.48"},1,1,"down","no"]
[12710,0,"chr1","-",160950553,160951474,"ENST00000490489",2,591,"ENSG00000158764","ITLN2","GO:0046872(metal ion binding);GO:0030246(carbohydrate binding);GO:0005576(extracellular region)","NA","NA","NA","intelectin 2 [Source:HGNC Symbol;Acc:HGNC:20599]",0,{"v":0.086111,"d":"0.09"},"-inf","-inf",1,1,"down","no"]
[4590,0,"chr1","-",39569495,39569990,"ENST00000492519",2,323,"MSTRG.440","PABPC4","GO:0003723(RNA binding);GO:0003676(nucleic acid binding);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0030529(intracellular ribonucleoprotein complex);GO:0005515(protein binding);GO:0007596(blood coagulation);GO:0005634(nucleus);GO:0006412(translation);GO:0006401(RNA catabolic process);GO:0006396(RNA processing);GO:0008143(poly(A) binding);GO:0008266(poly(U) RNA binding);GO:0010494(cytoplasmic stress granule)","03013(RNA transport);03015(mRNA surveillance pathway);03018(RNA degradation)","NA","NA","poly(A) binding protein cytoplasmic 4 [Source:HGNC Symbol;Acc:HGNC:8557]",{"v":0.266885,"d":"0.27"},{"v":0.029216,"d":"0.03"},{"v":9.13489184008762,"d":"9.13"},{"v":3.1913876470035,"d":"3.19"},1,1,"up","no"]
[141866,0,"chr3","-",154276029,154277835,"ENST00000495598",3,719,"ENSG00000174953","DHX36","GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0005829(cytosol);GO:0016787(hydrolase activity);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0004386(helicase activity);GO:0003677(DNA binding);GO:0005694(chromosome);GO:0000781(chromosome, telomeric region);GO:0005515(protein binding);GO:0001047(core promoter binding);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0070062(extracellular exosome);GO:0004004(ATP-dependent RNA helicase activity);GO:0001503(ossification);GO:0044212(transcription regulatory region DNA binding);GO:0010501(RNA secondary structure unwinding);GO:0070034(telomerase RNA binding);GO:0032481(positive regulation of type I interferon production);GO:0003697(single-stranded DNA binding);GO:0008094(DNA-dependent ATPase activity);GO:0042826(histone deacetylase binding);GO:0003725(double-stranded RNA binding);GO:0090669(telomerase RNA stabilization);GO:1902741(positive regulation of interferon-alpha secretion);GO:0051880(G-quadruplex DNA binding);GO:0032206(positive regulation of telomere maintenance);GO:0002151(G-quadruplex RNA binding);GO:0006396(RNA processing);GO:0009615(response to virus);GO:0043330(response to exogenous dsRNA);GO:0016020(membrane);GO:0016021(integral component of membrane)","03018(RNA degradation)","NA","NA","DEAH-box helicase 36 [Source:HGNC Symbol;Acc:HGNC:14410]",{"v":0.076354,"d":"0.08"},0,"inf","inf",1,1,"up","no"]
[188607,0,"chr9","-",121089,179012,"ENST00000612045",16,1813,"MSTRG.14648","CBWD1","GO:0000166(nucleotide binding);GO:0005524(ATP binding)","NA","NA","NA","COBW domain containing 1 [Source:HGNC Symbol;Acc:HGNC:17134]",0,{"v":0.140111,"d":"0.14"},"-inf","-inf",1,1,"down","no"]
[46759,0,"chr12","+",111744571,111747208,"ENST00000546647",3,774,"MSTRG.3726","ACAD10","GO:0008152(metabolic process);GO:0016787(hydrolase activity);GO:0016491(oxidoreductase activity);GO:0050660(flavin adenine dinucleotide binding);GO:0055114(oxidation-reduction process);GO:0016627(oxidoreductase activity, acting on the CH-CH group of donors);GO:0005739(mitochondrion);GO:0005759(mitochondrial matrix);GO:0006635(fatty acid beta-oxidation);GO:0003995(acyl-CoA dehydrogenase activity);GO:0033539(fatty acid beta-oxidation using acyl-CoA dehydrogenase)","NA","NA","NA","acyl-CoA dehydrogenase family member 10 [Source:HGNC Symbol;Acc:HGNC:21597]",0,0,1,0,1,1,"no","no"]
[138775,0,"chr3","+",105550220,105553171,"ENST00000489178",3,783,"ENSG00000170017","ALCAM","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0007155(cell adhesion);GO:0005886(plasma membrane);GO:0042995(cell projection);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0002376(immune system process);GO:0005925(focal adhesion);GO:0030425(dendrite);GO:0002250(adaptive immune response);GO:0005887(integral component of plasma membrane);GO:0030424(axon);GO:0070062(extracellular exosome);GO:0007165(signal transduction);GO:0031226(intrinsic component of plasma membrane);GO:0005102(receptor binding);GO:0001772(immunological synapse);GO:0048846(axon extension involved in axon guidance);GO:0031290(retinal ganglion cell axon guidance);GO:0007157(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules);GO:0042101(T cell receptor complex);GO:1990138(neuron projection extension);GO:0007411(axon guidance);GO:0008045(motor neuron axon guidance);GO:0009897(external side of plasma membrane);GO:0043025(neuronal cell body)","04514(Cell adhesion molecules (CAMs))","NA","NA","activated leukocyte cell adhesion molecule [Source:HGNC Symbol;Acc:HGNC:400]",{"v":0.091294,"d":"0.09"},0,"inf","inf",1,1,"up","no"]
[57514,0,"chr14","+",88572048,88611888,"ENST00000556000",13,2092,"ENSG00000100722","ZC3H14","GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016607(nuclear speck);GO:0046872(metal ion binding);GO:0005730(nucleolus);GO:0005515(protein binding);GO:0043488(regulation of mRNA stability);GO:0008143(poly(A) binding);GO:1900364(negative regulation of mRNA polyadenylation)","NA","NA","NA","zinc finger CCCH-type containing 14 [Source:HGNC Symbol;Acc:HGNC:20509]",{"v":0.311437,"d":"0.31"},{"v":0.034279,"d":"0.03"},{"v":9.08535838268328,"d":"9.09"},{"v":3.18354342439029,"d":"3.18"},1,1,"up","no"]
[30370,0,"chr11","-",62798845,62805440,"ENST00000526163",3,569,"MSTRG.2479","NXF1","GO:0005634(nucleus);GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0006810(transport);GO:0051028(mRNA transport);GO:0005737(cytoplasm);GO:0016607(nuclear speck);GO:0005654(nucleoplasm);GO:0005622(intracellular);GO:0005515(protein binding);GO:0006406(mRNA export from nucleus);GO:0005829(cytosol);GO:0016032(viral process);GO:0006405(RNA export from nucleus);GO:0000346(transcription export complex);GO:0003727(single-stranded RNA binding);GO:0016973(poly(A)+ mRNA export from nucleus);GO:0003729(mRNA binding);GO:0005487(nucleocytoplasmic transporter activity);GO:0005643(nuclear pore);GO:0042405(nuclear inclusion body)","03013(RNA transport);03015(mRNA surveillance pathway);03008(Ribosome biogenesis in eukaryotes);05164(Influenza A);05168(Herpes simplex infection)","NA","NA","nuclear RNA export factor 1 [Source:HGNC Symbol;Acc:HGNC:8071]",0,0,1,0,1,1,"no","no"]

{"sheet":"Table 7","index":6,"n_rows":1363,"n_cols":11,"rows_kept":1363}
["chr","start","end","gene_name","FPKM.T1","FPKM.T2","foldChange","foldChange2","qval","regulation","significant"]
["chr1",150572483,150579662,"MCL1",0.21,79.34,382.73,8.58,0,"up","yes"]
["chr3",46201709,46208396,"CCR1",0.31,45.87,147.34,7.2,0,"up","yes"]
["chr8",100916694,100953382,"YWHAZ",0.27,24.55,89.53,6.48,0,"up","yes"]
["chr16",172944,173463,"HBA2",6.01,432.35,71.95,6.17,0,"up","yes"]
["chr2",174559572,174634579,"WIPF1",0.71,44.51,62.52,5.97,0,"up","yes"]
["chr1",9651672,9729182,"PIK3CD",0.82,42.87,52.55,5.72,0,"up","yes"]
["chr6",41275204,41286719,"TREM1",0.46,21.55,47.36,5.57,0,"up","yes"]
["chr12",31959419,31996117,"KIAA1551",0.23,10.16,44.45,5.47,0,"up","yes"]
["chr4",1721421,1745061,"TACC3",0.39,17.59,45,5.49,0,"up","yes"]
["chr3",121663203,121749767,"GOLGB1",0.11,4.9,45.02,5.49,0,"up","yes"]
["chr2",85318027,85328251,"TGOLN2",0.69,27.34,39.54,5.31,0,"up","yes"]
["chr20",53567073,53609847,"ZNF217",0.18,7.01,39.08,5.29,0,"up","yes"]
["chr20",23626706,23637945,"CST3",0.31,12.1,38.51,5.27,0,"up","yes"]
["chr4",40424338,40629864,"RBM47",0.5,17.83,35.53,5.15,0,"up","yes"]
["chr6",108560866,108684768,"FOXO3",0.3,10.65,35.24,5.14,0,"up","yes"]
["chr1",154325553,154350945,"ATP8B2",0.42,14.24,34.17,5.09,0,"up","yes"]
["chr16",79789,138361,"NPRL3",0.84,27.13,32.41,5.02,0,"up","yes"]
["chr3",37243252,37366745,"GOLGA4",0.17,5.68,32.94,5.04,0,"up","yes"]
["chr8",38805480,38853121,"TACC1",0.29,9.21,31.4,4.97,0,"up","yes"]
["chr1",151156629,151159749,"TNFAIP8L2",0.66,20.97,31.7,4.99,0,"up","yes"]
["chr10",103088038,103187247,"NT5C2",0.28,8.48,30.58,4.93,0,"up","yes"]
["chrX",71118723,71142447,"MED12",0.15,4.62,30.43,4.93,0,"up","yes"]
["chr12",89588051,89709348,"ATP2B1",0.32,9.18,28.46,4.83,0,"up","yes"]
["chr16",71845991,71857333,"ATXN1L",0.28,7.87,28.41,4.83,0,"up","yes"]
["chr1",28914579,29117966,"EPB41",0.27,7.84,29.25,4.87,0,"up","yes"]
["chr11",65416571,65445540,"NEAT1",0.15,4.24,27.63,4.79,0,"up","yes"]
["chr8",99013266,99877580,"VPS13B",0.15,4.08,27.64,4.79,0,"up","yes"]
["chr11",64764390,64778534,"SF1",0.94,25.81,27.36,4.77,0,"up","yes"]
["chr17",81117295,81166017,"AATK",0.3,8.36,27.54,4.78,0,"up","yes"]
["chr6",6144072,6321686,"F13A1",0.3,8.16,27.54,4.78,0,"up","yes"]
["chr1",31906421,31938352,"PTP4A2",0.62,16.22,26,4.7,0,"up","yes"]
["chr16",30658431,30670814,"FBRS",0.43,10.7,25.07,4.65,0,"up","yes"]
["chr5",150486310,150554279,"NDST1",0.26,6.25,24.48,4.61,0,"up","yes"]
["chr12",10372353,10390018,"KLRK1",0.63,15.29,24.17,4.6,0,"up","yes"]
["chr17",31303766,31314112,"EVI2B",5.64,127.7,22.65,4.5,0,"up","yes"]
["chr1",202348699,202592706,"PPP1R12B",0.14,3.11,23.01,4.52,0,"up","yes"]
["chr6",31815543,31817946,"HSPA1A",0.42,9.93,23.6,4.56,0,"up","yes"]
["chr2",207074137,207167257,"KLF7",0.21,4.69,22.2,4.47,0,"up","yes"]
["chrX",149478766,149505327,"IDS",2.4,51.09,21.3,4.41,0,"up","yes"]
["chr1",51789196,51878040,"NRDC",1.12,24.28,21.61,4.43,0,"up","yes"]
["chr3",149812770,149962122,"RNF13",0.41,9.15,22.38,4.48,0,"up","yes"]
["chr6",138404433,138422108,"HEBP2",0.33,7.18,21.55,4.43,0,"up","yes"]
["chr1",43389895,43451152,"SZT2",0.17,3.62,21.51,4.43,0,"up","yes"]
["chr19",41265122,41307019,"HNRNPUL1",0.36,7.89,22.17,4.47,0,"up","yes"]
["chr8",97644546,97725243,"MTDH",0.43,9.4,21.72,4.44,0,"up","yes"]
["chr1",117605934,117628372,"FAM46C",0.28,5.6,20.24,4.34,0,"up","yes"]
["chr11",118436513,118523917,"KMT2A",0.27,5.38,19.87,4.31,0,"up","yes"]
["chr12",66302545,66347645,"HELB",0.1,2,20.44,4.35,0,"up","yes"]
["chr6",152121684,152637399,"SYNE1",0.08,1.58,19.36,4.27,0,"up","yes"]
["chr20",3786772,3806121,"CDC25B",0.27,5.36,20.22,4.34,0,"up","yes"]
["chr19",33373330,33382686,"CEBPG",0.27,5.15,19.35,4.27,0,"up","yes"]
["chr7",26190225,26200755,"HNRNPA2B1",1.09,20.16,18.53,4.21,0,"up","yes"]
["chr15",88638743,88656483,"ISG20",1.59,29.24,18.42,4.2,0,"up","yes"]
["chr1",150996086,151006404,"MINDY1",0.36,6.86,19.09,4.25,0,"up","yes"]
["chr1",26696007,26782102,"ARID1A",0.52,9.36,18,4.17,0,"up","yes"]
["chr1",12167003,12209228,"TNFRSF1B",1.04,18.68,17.99,4.17,0,"up","yes"]
["chr22",41621350,41664039,"XRCC6",1.16,20.91,17.97,4.17,0,"up","yes"]
["chr10",102133030,102150325,"PPRC1",0.2,3.63,18.26,4.19,0,"up","yes"]
["chr22",38734736,38755999,"SUN2",0.6,10.33,17.34,4.12,0,"up","yes"]
["chr3",142306607,142448062,"XRN1",0.11,1.95,17.98,4.17,0,"up","yes"]
["chr3",188225405,188890671,"LPP",0.14,2.4,17.24,4.11,0,"up","yes"]
["chr12",752584,909436,"WNK1",0.12,2.2,17.68,4.14,0,"up","yes"]
["chr6",11183298,11232682,"NEDD9",0.17,3.01,17.72,4.15,0,"up","yes"]
["chr6",85607785,85642922,"SYNCRIP",0.2,3.43,17.09,4.1,0,"up","yes"]
["chr9",135808487,135907224,"CAMSAP1",0.15,2.54,17.29,4.11,0,"up","yes"]
["chr10",102743970,102816240,"WBP1L",1.33,21.57,16.24,4.02,0,"up","yes"]
["chr1",175156987,175192793,"KIAA0040",1.86,29.67,15.92,3.99,0,"up","yes"]
["chr1",155688009,155739010,"DAP3",0.45,7.45,16.63,4.06,0,"up","yes"]
["chr16",28711527,28735597,"EIF3C",0.28,4.78,16.82,4.07,0,"up","yes"]
["chr2",230168918,230219950,"SP110",1.27,20.2,15.86,3.99,0,"up","yes"]
["chr7",30135053,30162762,"MTURN",0.42,6.62,15.88,3.99,0,"up","yes"]
["chr6",159669057,159693328,"SOD2",0.64,9.72,15.3,3.94,0,"up","yes"]
["chr3",124965710,125055958,"HEG1",0.17,2.66,15.27,3.93,0,"up","yes"]
["chr1",154405223,154466877,"IL6R",0.77,11.59,15.12,3.92,0,"up","yes"]
["chr10",78034251,78040714,"RPS24",9.39,137.86,14.67,3.88,0,"up","yes"]
["chr5",14143702,14510204,"TRIO",0.18,2.77,14.97,3.9,0,"up","yes"]
["chr17",31303494,31321884,"AC134669.2",0.63,9.48,14.94,3.9,0,"up","yes"]
["chr6",33272132,33276510,"RPS18",7.14,102.82,14.41,3.85,0,"up","yes"]
["chr14",75278817,75283215,"FOS",0.95,13.66,14.45,3.85,0,"up","yes"]
["chr15",43185439,43195195,"CCNDBP1",0.75,11.18,14.84,3.89,0,"up","yes"]
["chr3",187722320,187743672,"BCL6",0.59,8.4,14.22,3.83,0,"up","yes"]
["chr10",74826625,75032622,"KAT6B",0.18,2.68,14.53,3.86,0,"up","yes"]
["chr5",134115625,134148229,"TCF7",0.33,5.01,15.07,3.91,0,"up","yes"]
["chr7",140453047,140479336,"MKRN1",1.01,14.36,14.21,3.83,0,"up","yes"]
["chr6",159669057,159693587,"SOD2",0.7,9.69,13.92,3.8,0,"up","yes"]
["chr12",49791146,49828425,"NCKAP5L",0.18,2.69,14.77,3.88,0,"up","yes"]
["chr6",24839359,25042018,"RIPOR2",1.64,22.66,13.85,3.79,0,"up","yes"]
["chr17",81867721,81871406,"ARHGDIA",4.23,57.81,13.67,3.77,0,"up","yes"]
["chr5",70970050,71020710,"NAIP",0.21,3.05,14.72,3.88,0,"up","yes"]
["chr12",112125545,112153603,"TRAFD1",0.36,5.2,14.35,3.84,0,"up","yes"]
["chr1",25800176,25818224,"SELENON",0.19,2.74,14.15,3.82,0,"up","yes"]
["chr15",70049799,70097888,"TLE3",0.96,12.35,12.84,3.68,0,"up","yes"]
["chr11",64765652,64777760,"SF1",0.52,6.84,13.24,3.73,0,"up","yes"]
["chr4",48550502,48780248,"FRYL",0.18,2.42,13.43,3.75,0,"up","yes"]
["chr5",55940966,55994792,"IL6ST",0.32,4.21,13.32,3.74,0,"up","yes"]
["chr12",124911648,124915147,"UBC",2.05,25.7,12.52,3.65,0,"up","yes"]
["chr17",9913850,10198551,"GAS7",0.28,3.58,13,3.7,0,"up","yes"]
["chr1",28887099,29120040,"EPB41",0.43,5.46,12.65,3.66,0,"up","yes"]
["chr7",101816011,102258233,"CUX1",0.3,3.69,12.5,3.64,0,"up","yes"]
["chr9",109015152,109119945,"TMEM245",0.4,4.95,12.52,3.65,0,"up","yes"]
["chr21",43865186,43986536,"AGPAT3",0.28,3.55,12.7,3.67,0,"up","yes"]
["chr1",54053601,54106082,"TCEANC2",0.1,1.29,12.89,3.69,0,"up","yes"]
["chr6",89080713,89084839,"PNRC1",7.58,92.37,12.18,3.61,0,"up","yes"]
["chr3",15003915,15049273,"NR2C2",0.33,4.11,12.41,3.63,0,"up","yes"]
["chr12",7132386,7158932,"CLSTN3",0.22,2.9,12.99,3.7,0,"up","yes"]
["chr2",69457997,69509280,"AAK1",0.46,5.6,12.19,3.61,0,"up","yes"]
["chr19",39825715,39834158,"DYRK1B",0.47,6.05,12.82,3.68,0,"up","yes"]
["chr17",68268197,68291266,"SLC16A6",0.3,3.83,12.86,3.68,0,"up","yes"]
["chr13",27435643,27450574,"MTIF3",0.9,11.54,12.89,3.69,0,"up","yes"]
["chr10",11165140,11330639,"CELF2",1.61,19.51,12.15,3.6,0,"up","yes"]
["chr9",95444162,95507417,"PTCH1",0.24,2.93,12.38,3.63,0,"up","yes"]
["chr14",92936914,93115803,"ITPK1",1.79,21.24,11.89,3.57,0,"up","yes"]
["chr14",73275216,73458522,"NUMB",0.57,6.88,11.98,3.58,0,"up","yes"]
["chr17",67825664,67984378,"BPTF",0.23,2.66,11.64,3.54,0,"up","yes"]
["chr20",53568920,53592754,"ZNF217",1.23,13.97,11.38,3.51,0,"up","yes"]
["chr4",10074339,10116860,"WDR1",0.79,9.05,11.41,3.51,0,"up","yes"]
["chr2",170992154,171160495,"TLK1",0.41,4.7,11.45,3.52,0,"up","yes"]
["chr11",47269684,47329357,"MADD",0.17,1.94,11.64,3.54,0,"up","yes"]
["chr9",112218435,112333667,"PTBP3",1.34,14.69,10.93,3.45,0,"up","yes"]
["chr1",226061851,226071523,"H3F3A",10.1,109.45,10.84,3.44,0,"up","yes"]
["chr6",31620725,31637771,"PRRC2A",0.97,10.49,10.85,3.44,0,"up","yes"]
["chr21",33543065,33559056,"SON",0.56,6.08,10.78,3.43,0,"up","yes"]
["chr20",5544439,5586037,"GPCPD1",0.39,4.27,10.86,3.44,0,"up","yes"]
["chr10",73785624,73801797,"ZSWIM8",0.3,3.34,10.97,3.46,0,"up","yes"]
["chrX",130064874,130110716,"ELF4",0.36,3.95,10.98,3.46,0,"up","yes"]
["chr6",159682139,159693241,"SOD2",2.25,24.48,10.89,3.44,0,"up","yes"]
["chr12",46183063,46269012,"SLC38A1",0.69,7.35,10.64,3.41,0,"up","yes"]
["chr7",50304782,50402525,"IKZF1",0.5,5.47,10.91,3.45,0,"up","yes"]
["chr8",143574787,143578339,"NAPRT",0.43,4.81,11.28,3.5,0,"up","yes"]
["chr21",46235133,46268062,"MCM3AP",0.17,1.94,11.21,3.49,0,"up","yes"]
["chr2",190408355,190502315,"MFSD6",0.28,2.98,10.77,3.43,0,"up","yes"]
["chr19",10808519,10831897,"DNM2",0.23,2.44,10.84,3.44,0,"up","yes"]
["chr5",134113330,134148918,"TCF7",0.74,7.71,10.46,3.39,0,"up","yes"]
["chr6",159679116,159693228,"SOD2",6.19,64.32,10.39,3.38,0,"up","yes"]
["chr6",158765741,158818227,"EZR",2.59,26.69,10.3,3.36,0,"up","yes"]
["chr14",50719763,50831121,"NIN",0.7,7.18,10.25,3.36,0,"up","yes"]
["chr11",75434640,75525903,"GDPD5",0.22,2.38,11.05,3.47,0,"up","yes"]
["chr5",149345430,149354583,"GRPEL2",0.32,3.36,10.61,3.41,0,"up","yes"]
["chr10",73744384,73772159,"SEC24C",0.52,5.39,10.4,3.38,0,"up","yes"]
["chr1",235167884,235328134,"ARID4B",0.15,1.59,10.92,3.45,0,"up","yes"]
["chr4",87007396,87135701,"AFF1",0.97,9.91,10.23,3.35,0,"up","yes"]
["chr14",20781051,20782467,"RNASE6",0.78,8.39,10.76,3.43,0,"up","yes"]
["chr19",35448269,35453515,"FFAR2",2.09,21.02,10.08,3.33,0,"up","yes"]
["chr2",216498867,216501467,"RPL37A",4.07,41.42,10.18,3.35,0,"up","yes"]
["chr14",22488593,22552158,"TRAC",4.19,42.17,10.07,3.33,0,"up","yes"]
["chr19",54449103,54462037,"LENG8",0.35,3.61,10.19,3.35,0,"up","yes"]
["chrX",47624214,47630305,"CFP",0.85,8.86,10.42,3.38,0,"up","yes"]
["chr3",197950194,197955851,"RPL35A",24.13,239.59,9.93,3.31,0,"up","yes"]
["chr8",20197367,20226844,"ATP6V1B2",2.57,25.39,9.89,3.31,0,"up","yes"]
["chr9",133097720,133149334,"RALGDS",0.38,3.88,10.28,3.36,0,"up","yes"]
["chr17",67825665,67983153,"BPTF",0.24,2.39,10.08,3.33,0,"up","yes"]
["chr8",93729356,93741017,"RBM12B",0.17,1.78,10.34,3.37,0,"up","yes"]
["chr1",207496157,207640647,"CR1",0.71,6.99,9.89,3.31,0,"up","yes"]
["chr14",21385486,21456080,"CHD8",1.13,11.01,9.77,3.29,0,"up","yes"]
["chr12",120534365,120577594,"RNF10",1.19,11.69,9.82,3.3,0,"up","yes"]
["chr16",88696536,88703617,"RNF166",0.34,3.49,10.3,3.36,0,"up","yes"]
["chrX",120625793,120630150,"C1GALT1C1",0.53,5.55,10.41,3.38,0,"up","yes"]
["chr13",49444374,49495003,"SETDB2",0.22,2.15,9.96,3.32,0,"up","yes"]
["chr6",132744196,132763447,"VNN2",0.82,8.11,9.93,3.31,0,"up","yes"]
["chr2",190975537,191014168,"STAT1",0.5,4.92,9.83,3.3,0,"up","yes"]
["chr1",155002657,155018522,"ZBTB7B",0.78,7.43,9.55,3.25,0,"up","yes"]
["chr19",54200742,54207647,"RPS9",20.53,191.3,9.32,3.22,0,"up","yes"]
["chr1",151612082,151699074,"SNX27",1.02,9.54,9.37,3.23,0,"up","yes"]
["chr11",117986737,118003037,"IL10RA",1.84,17.09,9.29,3.22,0,"up","yes"]
["chr3",184314495,184335353,"EIF4G1",1.95,18.11,9.29,3.22,0,"up","yes"]
["chr1",161505430,161527118,"FCGR2A",2.22,20.51,9.25,3.21,0,"up","yes"]
["chr19",18110137,18150640,"MAST3",0.32,3.07,9.62,3.27,0,"up","yes"]
["chr15",90902860,90922733,"MAN2A2",0.94,8.73,9.32,3.22,0,"up","yes"]
["chr5",42985082,42993323,".",0.82,7.78,9.46,3.24,0,"up","yes"]
["chr1",148531490,148560644,"NBPF14",1.48,13.69,9.26,3.21,0,"up","yes"]
["chr3",196347662,196432474,"UBXN7",0.68,6.24,9.21,3.2,0,"up","yes"]
["chr4",139716753,140154184,"MAML3",0.38,3.56,9.33,3.22,0,"up","yes"]
["chr14",76762189,76783015,"VASH1",0.32,2.98,9.4,3.23,0,"up","yes"]
["chr17",48048363,48061487,"NFE2L1",0.29,2.82,9.55,3.26,0,"up","yes"]
["chr3",4493350,4847506,"ITPR1",0.58,5.27,9.17,3.2,0,"up","yes"]
["chr7",88270933,88306895,"STEAP4",1.06,9.69,9.11,3.19,0,"up","yes"]
["chr5",175658056,175710766,"HRH2",0.25,2.42,9.49,3.25,0,"up","yes"]
["chr19",54449187,54462037,"LENG8",0.38,3.51,9.28,3.21,0,"up","yes"]
["chr16",30184748,30187083,"CORO1A",2.19,20.5,9.38,3.23,0,"up","yes"]
["chr16",21879338,21916024,"SMG1P4",0.21,1.99,9.6,3.26,0,"up","yes"]
["chr3",151326235,151329552,"P2RY13",1,9.28,9.27,3.21,0,"up","yes"]
["chr5",83052846,83077496,"TMEM167A",1.48,13.34,9.02,3.17,0,"up","yes"]
["chr14",23058567,23069525,"ACIN1",0.54,5,9.22,3.2,0,"up","yes"]
["chr12",6570172,6607322,"CHD4",0.59,5.38,9.09,3.18,0,"up","yes"]
["chrX",153947553,153971807,"HCFC1",0.87,7.79,8.91,3.15,0,"up","yes"]
["chr1",109620654,109632051,"AMPD2",0.3,2.81,9.25,3.21,0,"up","yes"]
["chr4",150314723,151015277,"LRBA",0.58,5.18,8.87,3.15,0,"up","yes"]
["chr19",51410021,51417803,"SIGLEC10",0.68,6.08,8.96,3.16,0,"up","yes"]
["chr18",79069394,79378283,"ATP9B",0.22,2.03,9.29,3.22,0,"up","yes"]
["chr11",33858576,33865151,"LMO2",1.78,15.77,8.87,3.15,0,"up","yes"]
["chr2",151247940,151261879,"RBM43",0.22,2.06,9.25,3.21,0,"up","yes"]
["chr17",7888791,7912760,"CHD3",0.51,4.51,8.75,3.13,0,"up","yes"]
["chr3",15667236,15859771,"ANKRD28",0.16,1.49,9.03,3.17,0,"up","yes"]
["chr16",58543327,58629838,"CNOT1",0.16,1.45,9.18,3.2,0,"up","yes"]
["chr11",63839295,63909573,"MARK2",0.53,4.68,8.89,3.15,0,"up","yes"]
["chr9",111661335,111670246,"GNG10",4.75,40.75,8.58,3.1,0,"up","yes"]
["chr19",35154730,35166761,"FXYD5",0.76,6.99,9.24,3.21,0,"up","yes"]
["chrX",12906632,12913805,"TLR8",0.66,5.75,8.69,3.12,0,"up","yes"]
["chr20",32443059,32483471,"NOL4L",0.3,2.63,8.66,3.11,0,"up","yes"]
["chr12",49002281,49060107,"KMT2D",0.99,8.28,8.39,3.07,0,"up","yes"]
["chr5",76170738,76174209,"AC113404.3",1.52,13.21,8.66,3.11,0,"up","yes"]
["chr14",24136227,24138967,"PSME1",2.81,24.02,8.54,3.09,0,"up","yes"]
["chr3",184315166,184335358,"EIF4G1",0.13,1.2,8.98,3.17,0,"up","yes"]
["chr12",123295905,123364828,"SBNO1",0.88,7.45,8.44,3.08,0,"up","yes"]
["chr1",155688009,155739010,"DAP3",1.13,9.62,8.5,3.09,0,"up","yes"]
["chr11",65653596,65663094,"RELA",1.79,14.95,8.36,3.06,0,"up","yes"]
["chr1",15847864,15940460,"SPEN",1.24,10.25,8.26,3.05,0,"up","yes"]
["chr12",57096200,57111346,"STAT6",0.58,4.97,8.51,3.09,0,"up","yes"]
["chr17",7839962,7853680,"KDM6B",3.36,27.57,8.2,3.04,0,"up","yes"]
["chr12",53452311,53475553,"PCBP2",1.3,10.95,8.41,3.07,0,"up","yes"]
["chr3",196739619,196832488,"PAK2",0.97,8.03,8.26,3.05,0,"up","yes"]
["chr17",75456641,75500090,"TMEM94",0.22,1.92,8.55,3.1,0,"up","yes"]
["chr22",31618491,31628221,"PISD",0.38,3.25,8.59,3.1,0,"up","yes"]
["chr20",17941597,17968720,"SNX5",1.07,8.91,8.31,3.05,0,"up","yes"]
["chr8",100703035,100722092,"PABPC1",9.43,76.24,8.09,3.02,0,"up","yes"]
["chr2",219219380,219229626,"ATG9A",0.24,2.09,8.71,3.12,0,"up","yes"]
["chr1",232983435,233295713,"PCNX2",0.18,1.49,8.4,3.07,0,"up","yes"]
["chr22",31618491,31662215,"PISD",0.3,2.58,8.7,3.12,0,"up","yes"]
["chr22",50274979,50307627,"PLXNB2",0.54,4.41,8.18,3.03,0,"up","yes"]
["chr15",89784889,89815397,"ANPEP",2.66,21.42,8.06,3.01,0,"up","yes"]
["chr1",66999332,67054099,"SLC35D1",0.3,2.5,8.24,3.04,0,"up","yes"]
["chr14",105419822,105470729,"MTA1",0.58,4.84,8.32,3.06,0,"up","yes"]
["chr12",6570130,6607476,"CHD4",0.59,4.8,8.11,3.02,0,"up","yes"]
["chr13",79318868,79406221,"RBM26",0.17,1.48,8.58,3.1,0,"up","yes"]
["chr1",120813906,120841481,"NBPF26",0.33,2.72,8.38,3.07,0,"up","yes"]
["chr20",3796291,3806115,"CDC25B",0.55,4.49,8.21,3.04,0,"up","yes"]
["chr6",24804282,24936052,"RIPOR2",0.51,4.1,8.08,3.01,0,"up","yes"]
["chr10",128047561,128085855,"PTPRE",0.53,4.3,8.11,3.02,0,"up","yes"]
["chr7",139572629,139777778,"HIPK2",0.4,3.26,8.14,3.02,0,"up","yes"]
["chr14",92513793,92688041,"RIN3",0.46,3.82,8.23,3.04,0,"up","yes"]
["chr6",63635788,63714266,"PHF3",1.9,14.94,7.86,2.98,0,"up","yes"]
["chr14",70907739,71110118,"PCNX1",0.61,4.83,7.95,2.99,0,"up","yes"]
["chr12",56598369,56630211,"BAZ2A",2.64,20.7,7.85,2.97,0,"up","yes"]
["chr2",207529892,207603431,"CREB1",0.54,4.32,7.92,2.99,0,"up","yes"]
["chr7",135165798,135170790,"C7orf49",0.67,5.41,8.14,3.02,0,"up","yes"]
["chr15",48988770,49046433,"SECISBP2L",0.18,1.5,8.14,3.03,0,"up","yes"]
["chr14",23059059,23095383,"ACIN1",0.48,3.86,8.02,3,0,"up","yes"]
["chr17",1568808,1629114,"SLC43A2",1.3,10.11,7.8,2.96,0,"up","yes"]
["chr12",95973847,95996344,"HAL",0.43,3.47,8.15,3.03,0,"up","yes"]
["chr14",76151936,76214343,"GPATCH2L",0.52,4.01,7.73,2.95,0,"up","yes"]
["chr6",130144318,130222954,"SAMD3",1.25,9.79,7.81,2.96,0,"up","yes"]
["chr17",45508109,45550335,"LRRC37A4P",0.18,1.45,8.16,3.03,0,"up","yes"]
["chr4",67493405,67545503,"CENPC",0.43,3.42,7.98,3,0,"up","yes"]
["chr8",143915153,143976734,"PLEC",0.92,7.04,7.64,2.93,0,"up","yes"]
["chr19",53333749,53354869,"ZNF845",0.18,1.5,8.24,3.04,0,"up","yes"]
["chr2",215312072,215349763,"ATIC",0.45,3.62,8.12,3.02,0,"up","yes"]
["chr6",33420255,33451842,"SYNGAP1",0.25,1.98,7.99,3,0,"up","yes"]
["chr12",76355836,76559809,"OSBPL8",3.3,24.94,7.55,2.92,0,"up","yes"]
["chr2",241315100,241354024,"2-Sep",1.2,9.16,7.62,2.93,0,"up","yes"]
["chr17",45231427,45239054,"FMNL1",1.11,8.81,7.97,2.99,0,"up","yes"]
["chr13",21373571,21459330,"ZDHHC20",0.75,5.65,7.57,2.92,0,"up","yes"]
["chr16",1809103,1826841,"HAGH",2.91,21.87,7.51,2.91,0,"up","yes"]
["chr7",100466507,100479169,"TSC22D4",0.4,3.12,7.77,2.96,0,"up","yes"]
["chr4",48497363,48780299,"FRYL",0.74,5.49,7.44,2.89,0,"up","yes"]
["chr22",19717220,19724216,"5-Sep",0.94,7.05,7.47,2.9,0,"up","yes"]
["chr20",51386957,51542719,"NFATC2",0.94,7,7.42,2.89,0,"up","yes"]
["chr17",31937067,32000649,"SUZ12",0.27,2.08,7.77,2.96,0,"up","yes"]
["chr19",48615366,48619177,"RPL18",1.39,10.7,7.67,2.94,0,"up","yes"]
["chr11",47358181,47378487,"SPI1",1.22,9.27,7.62,2.93,0,"up","yes"]
["chr11",9384628,9445661,"IPO7",0.47,3.55,7.57,2.92,0,"up","yes"]
["chr10",73785662,73801792,"ZSWIM8",0.4,2.97,7.51,2.91,0,"up","yes"]
["chr1",207496228,207640208,"CR1",0.9,6.62,7.38,2.88,0,"up","yes"]
["chr9",129812944,129824134,"TOR1A",0.61,4.68,7.63,2.93,0,"up","yes"]
["chrX",20150562,20266721,"RPS6KA3",0.43,3.23,7.59,2.92,0,"up","yes"]
["chr3",15667239,15859422,"ANKRD28",0.33,2.5,7.64,2.93,0,"up","yes"]
["chr11",119660992,119729084,"NECTIN1",0.29,2.2,7.54,2.91,0,"up","yes"]
["chr8",47773108,47960183,"PRKDC",0.67,4.94,7.32,2.87,0,"up","yes"]
["chr7",128392278,128409982,"IMPDH1",0.69,5.21,7.54,2.91,0,"up","yes"]
["chr6",44127639,44149261,"TMEM63B",0.72,5.44,7.59,2.92,0,"up","yes"]
["chr2",173908530,173964219,"SP3",1.19,8.67,7.3,2.87,0.01,"up","yes"]
["chr20",62877738,62937952,"DIDO1",0.35,2.56,7.37,2.88,0.01,"up","yes"]
["chr16",69566062,69697840,"NFAT5",0.13,1,7.69,2.94,0.01,"up","yes"]
["chr7",135662521,135676412,"C7orf73",2.08,15.16,7.28,2.86,0.01,"up","yes"]
["chr22",31619103,31662432,"PISD",0.92,6.82,7.44,2.9,0.01,"up","yes"]
["chr16",21447078,21501886,"SMG1P3",0.26,2,7.62,2.93,0.01,"up","yes"]
["chr22",50446806,50474942,"SBF1",0.8,5.84,7.25,2.86,0.01,"up","yes"]
["chr6",43511827,43516990,"YIPF3",5.17,37.29,7.21,2.85,0.01,"up","yes"]
["chr15",59663366,59689280,"BNIP2",2.89,20.88,7.22,2.85,0.01,"up","yes"]
["chr1",153959099,153963572,"SLC39A1",2.29,16.55,7.22,2.85,0.01,"up","yes"]
["chr20",23633657,23638473,"CST3",7.2,51.76,7.19,2.85,0.01,"up","yes"]
["chr12",39294387,39443059,"KIF21A",0.21,1.54,7.5,2.91,0.01,"up","yes"]
["chr11",62515905,62546835,"AHNAK",10.82,76.84,7.1,2.83,0.01,"up","yes"]
["chr19",2037604,2050915,"MKNK2",1.16,8.35,7.21,2.85,0.01,"up","yes"]
["chr14",99481407,99510311,"CCNK",1.85,13.4,7.25,2.86,0.01,"up","yes"]
["chr9",125261843,125363105,"GAPVD1",0.48,3.48,7.28,2.86,0.01,"up","yes"]
["chr17",50965644,51120865,"SPAG9",1.51,10.77,7.14,2.84,0.01,"up","yes"]
["chr5",141653401,141682203,"ARAP3",0.23,1.74,7.46,2.9,0.01,"up","yes"]
["chr9",112218604,112333620,"PTBP3",0.27,1.98,7.31,2.87,0.01,"up","yes"]
["chr2",212999691,213151609,"IKZF2",0.2,1.48,7.31,2.87,0.01,"up","yes"]
["chr13",112690329,112887168,"ATP11A",0.35,2.54,7.17,2.84,0.01,"up","yes"]
["chr10",128047561,128085855,"PTPRE",0.26,2,7.56,2.92,0.01,"up","yes"]
["chr7",44796680,44800011,"PPIA",1.88,13.92,7.4,2.89,0.01,"up","yes"]
["chr15",42495260,42533061,"SNAP23",3.12,22.03,7.05,2.82,0.01,"up","yes"]
["chr2",28392802,28417312,"FOSL2",0.14,1.05,7.5,2.91,0.01,"up","yes"]
["chr15",75023555,75050726,"PPCDC",0.42,3.16,7.47,2.9,0.01,"up","yes"]
["chr6",24804285,24910967,"RIPOR2",0.61,4.33,7.1,2.83,0.01,"up","yes"]
["chr22",41091786,41180079,"EP300",1.75,12.25,7,2.81,0.01,"up","yes"]
["chr7",100852721,100867010,"SLC12A9",1.28,9.05,7.06,2.82,0.01,"up","yes"]
["chr17",7558441,7571822,"SENP3-EIF4A1",1.45,10.16,7.01,2.81,0.01,"up","yes"]
["chr12",752593,911300,"WNK1",0.53,3.74,7.04,2.81,0.01,"up","yes"]
["chr1",75724706,75762954,"ACADM",0.89,6.43,7.26,2.86,0.01,"up","yes"]
["chr15",43185940,43195192,"CCNDBP1",0.52,3.93,7.5,2.91,0.01,"up","yes"]
["chr7",72925122,72946234,"POM121",0.68,4.85,7.11,2.83,0.01,"up","yes"]
["chr12",55743280,55757278,"GDF11",0.17,1.24,7.25,2.86,0.01,"up","yes"]
["chr1",24643308,24671595,"SRRM1",0.34,2.52,7.45,2.9,0.01,"up","yes"]
["chr11",117144267,117171048,"PAFAH1B2",1.59,11.08,6.98,2.8,0.01,"up","yes"]
["chr15",75201877,75212169,"C15orf39",5.53,38.05,6.88,2.78,0.01,"up","yes"]
["chr19",17860125,17863243,"RPL18A",4.45,31.13,6.99,2.81,0.01,"up","yes"]
["chr4",705765,770640,"PCGF3",0.45,3.16,7,2.81,0.01,"up","yes"]
["chr5",88195206,88268848,"TMEM161B",0.3,2.2,7.36,2.88,0.01,"up","yes"]
["chr17",50150696,50151009,".",3.7,26.53,7.17,2.84,0.01,"up","yes"]
["chr11",44727112,44931332,"TSPAN18",0.34,2.44,7.2,2.85,0.01,"up","yes"]
["chr11",124753123,124762280,"ESAM",0.57,4.1,7.24,2.86,0.01,"up","yes"]
["chr21",34787801,35049298,"RUNX1",0.69,4.77,6.89,2.79,0.01,"up","yes"]
["chr21",33542618,33577481,"SON",0.6,4.14,6.88,2.78,0.01,"up","yes"]
["chr1",45511036,45521938,"PRDX1",0.66,4.8,7.31,2.87,0.01,"up","yes"]
["chr19",41264417,41306991,"HNRNPUL1",0.56,3.91,7.01,2.81,0.01,"up","yes"]
["chr14",24136200,24138964,"PSME1",3.34,22.88,6.86,2.78,0.01,"up","yes"]
["chr10",70147289,70170523,"SAR1A",0.15,1.11,7.25,2.86,0.01,"up","yes"]
["chr14",39175213,39183218,"PNN",1.4,9.51,6.82,2.77,0.01,"up","yes"]
["chr1",248838280,248849517,"ZNF672",0.73,5.08,6.92,2.79,0.01,"up","yes"]
["chr17",74776483,74839779,"TMEM104",0.48,3.3,6.91,2.79,0.01,"up","yes"]
["chr11",119206276,119308149,"CBL",2.18,14.66,6.73,2.75,0.01,"up","yes"]
["chrX",73820656,73852753,"XIST",1.94,13.05,6.73,2.75,0.01,"up","yes"]
["chr11",108287392,108366034,"ATM",0.87,5.92,6.8,2.77,0.01,"up","yes"]
["chr1",119911553,120069626,"NOTCH2",4.76,31.95,6.71,2.75,0.01,"up","yes"]
["chr1",46607725,46616465,"MOB3C",0.14,1.02,7.2,2.85,0.01,"up","yes"]
["chr17",78113076,78128772,"TMC6",0.42,2.96,6.98,2.8,0.01,"up","yes"]
["chr7",50304054,50405097,"IKZF1",0.36,2.47,6.89,2.78,0.01,"up","yes"]
["chr9",77177445,77421541,"VPS13A",0.27,1.82,6.76,2.76,0.01,"up","yes"]
["chr11",59148245,59155036,"FAM111A",0.37,2.54,6.94,2.79,0.01,"up","yes"]
["chr10",8054806,8074890,"GATA3",0.32,2.25,7.14,2.84,0.01,"up","yes"]
["chr12",14365632,14502935,"ATF7IP",1.54,10.27,6.69,2.74,0.01,"up","yes"]
["chr16",85801,138512,"NPRL3",1.87,12.58,6.72,2.75,0.01,"up","yes"]
["chr8",143574785,143597429,"NAPRT",5.88,39.14,6.66,2.73,0.01,"up","yes"]
["chr5",131264009,131394687,"CDC42SE2",0.6,4.12,6.83,2.77,0.01,"up","yes"]
["chr14",75661278,75955078,"TTLL5",0.17,1.22,7.15,2.84,0.01,"up","yes"]
["chr3",47381020,47413441,"PTPN23",0.44,3.01,6.8,2.77,0.01,"up","yes"]
["chr15",65446619,65517699,"DPP8",0.75,5.13,6.8,2.77,0.01,"up","yes"]
["chr7",47275154,47582144,"TNS3",0.34,2.33,6.76,2.76,0.01,"up","yes"]
["chr16",31180110,31194871,"FUS",1.58,10.52,6.67,2.74,0.01,"up","yes"]
["chr19",49907543,49929731,"NUP62",0.3,2.09,7.04,2.82,0.01,"up","yes"]
["chr17",35010042,35089264,"AC004223.3",0.3,2.14,7.09,2.82,0.01,"up","yes"]
["chr2",201260521,201287586,"CASP8",4.53,30.03,6.63,2.73,0.01,"up","yes"]
["chr21",41988637,42010387,"ZBTB21",0.21,1.48,6.92,2.79,0.01,"up","yes"]
["chr12",49185010,49186864,"TUBA1A",3.14,20.89,6.65,2.73,0.01,"up","yes"]
["chr9",83244622,83538438,"FRMD3",0.16,1.16,7.04,2.81,0.01,"up","yes"]
["chr5",173888318,173959809,"CPEB4",0.68,4.52,6.61,2.72,0.01,"up","yes"]
["chr10",35449711,35571080,"CCNY",2.48,16.29,6.57,2.71,0.01,"up","yes"]
["chr1",148102047,148127288,"NBPF11",0.17,1.21,6.95,2.8,0.01,"up","yes"]
["chr16",15593901,15643060,"MARF1",0.51,3.39,6.59,2.72,0.01,"up","yes"]
["chr10",11165484,11329289,"CELF2",1.24,8.3,6.71,2.75,0.01,"up","yes"]
["chr12",109947322,109996296,"GIT2",1.73,11.29,6.54,2.71,0.01,"up","yes"]
["chr17",4959226,4967790,"SPAG7",0.89,6.15,6.9,2.79,0.01,"up","yes"]
["chr22",24270840,24417740,"SPECC1L",0.64,4.16,6.54,2.71,0.01,"up","yes"]
["chr8",143915147,143939590,"PLEC",0.95,6.13,6.46,2.69,0.01,"up","yes"]
["chr11",46347588,46380367,"DGKZ",0.28,1.93,6.84,2.77,0.01,"up","yes"]
["chr16",3725054,3880726,"CREBBP",3.4,21.75,6.41,2.68,0.01,"up","yes"]
["chr8",60678778,60868028,"CHD7",0.47,3.03,6.47,2.69,0.01,"up","yes"]
["chr18",62523667,62586729,"ZCCHC2",0.27,1.79,6.64,2.73,0.01,"up","yes"]
["chr17",16029157,16215549,"NCOR1",0.34,2.18,6.48,2.7,0.01,"up","yes"]
["chr4",73075686,73258798,"ANKRD17",0.77,4.92,6.41,2.68,0.01,"up","yes"]
["chr15",55359018,55408052,"CCPG1",0.43,2.85,6.67,2.74,0.01,"up","yes"]
["chr19",1573596,1592801,"MBD3",0.39,2.57,6.55,2.71,0.01,"up","yes"]
["chr14",103121459,103137439,"TNFAIP2",7.25,46.04,6.35,2.67,0.01,"up","yes"]
["chr18",79400336,79529323,"NFATC1",0.78,5.06,6.45,2.69,0.01,"up","yes"]
["chr22",20507610,20587619,"MED15",2.85,18.17,6.38,2.67,0.01,"up","yes"]
["chrX",44873511,45112602,"KDM6A",0.68,4.41,6.44,2.69,0.01,"up","yes"]
["chr17",74737217,74747300,"RAB37",3.48,22.19,6.38,2.67,0.01,"up","yes"]
["chr1",120805418,120840619,"NBPF26",0.43,2.87,6.63,2.73,0.01,"up","yes"]
["chr16",15865720,15888615,"FOPNL",0.98,6.37,6.48,2.7,0.01,"up","yes"]
["chr7",44044717,44061716,"DBNL",3.21,20.45,6.37,2.67,0.01,"up","yes"]
["chr1",154582067,154608198,"ADAR",4.11,25.93,6.31,2.66,0.01,"up","yes"]
["chr2",201116104,201176687,"CFLAR",1.98,12.46,6.3,2.65,0.01,"up","yes"]
["chr1",1751232,1780502,"NADK",8.24,51.92,6.3,2.65,0.01,"up","yes"]
["chr7",90709531,91210585,"CDK14",0.22,1.46,6.65,2.73,0.01,"up","yes"]
["chrX",123860027,123913979,"XIAP",0.48,3.04,6.37,2.67,0.01,"up","yes"]
["chr5",177133079,177300210,"NSD1",0.56,3.54,6.33,2.66,0.01,"up","yes"]
["chr8",26382898,26413129,"BNIP3L",5.74,36.01,6.27,2.65,0.01,"up","yes"]
["chr11",68154863,68213415,"KMT5B",0.43,2.76,6.41,2.68,0.01,"up","yes"]
["chr1",113761833,113812448,"RSBN1",0.33,2.13,6.43,2.69,0.01,"up","yes"]
["chr1",113761832,113812476,"RSBN1",0.33,2.12,6.43,2.69,0.01,"up","yes"]
["chr1",144425517,144461674,"NBPF15",0.34,2.25,6.6,2.72,0.01,"up","yes"]
["chr19",39834453,39846384,"FBL",2.41,15.41,6.39,2.68,0.01,"up","yes"]
["chr1",24899518,24929877,"RUNX3",4.29,26.69,6.22,2.64,0.01,"up","yes"]
["chr12",47841539,47905031,"VDR",0.4,2.59,6.43,2.68,0.01,"up","yes"]
["chr1",21218584,21279549,"ECE1",0.34,2.19,6.5,2.7,0.01,"up","yes"]
["chr3",167684339,167734510,"PDCD10",1.35,8.82,6.54,2.71,0.01,"up","yes"]
["chrX",71910818,72153286,"NHSL2",1.35,8.36,6.2,2.63,0.01,"up","yes"]
["chr3",17158522,17742623,"TBC1D5",0.43,2.74,6.39,2.68,0.01,"up","yes"]
["chr19",58551566,58554973,"CHMP2A",1.56,10.15,6.51,2.7,0.01,"up","yes"]
["chr11",74454841,74467628,"KCNE3",0.6,3.85,6.4,2.68,0.01,"up","yes"]
["chr2",173909941,173963835,"SP3",2.07,12.96,6.26,2.65,0.01,"up","yes"]
["chr8",30063012,30083207,"SARAF",18.83,116.32,6.18,2.63,0.01,"up","yes"]
["chr14",73275210,73355769,"NUMB",0.45,2.88,6.43,2.68,0.01,"up","yes"]
["chr19",42268537,42295796,"CIC",0.46,2.84,6.23,2.64,0.01,"up","yes"]
["chr6",18387350,18468874,"RNF144B",1.51,9.34,6.18,2.63,0.01,"up","yes"]
["chr14",89156172,89619130,"FOXN3",1.18,7.25,6.16,2.62,0.01,"up","yes"]
["chrX",101009542,101052083,"TRMT2B",0.59,3.73,6.31,2.66,0.01,"up","yes"]
["chr20",3795739,3805237,"CDC25B",0.81,5.13,6.34,2.66,0.01,"up","yes"]
["chr22",29883213,30026495,"MTMR3",0.17,1.11,6.57,2.72,0.01,"up","yes"]
["chr15",74798652,74802589,"CSK",0.64,4.13,6.46,2.69,0.01,"up","yes"]
["chr12",105174208,105236083,"APPL2",0.39,2.53,6.53,2.71,0.01,"up","yes"]
["chr1",42682987,42702349,"YBX1",10.7,65.08,6.08,2.6,0.01,"up","yes"]
["chr10",63167590,63269066,"JMJD1C",1.74,10.57,6.08,2.6,0.01,"up","yes"]
["chr8",132775358,132845923,"PHF20L1",0.43,2.69,6.29,2.65,0.01,"up","yes"]
["chr19",39433207,39435936,"RPS16",1.26,8.21,6.5,2.7,0.01,"up","yes"]
["chr7",124822387,124929983,"POT1",0.31,1.96,6.34,2.66,0.01,"up","yes"]
["chr6",134169284,134174842,"SGK1",0.88,5.45,6.19,2.63,0.01,"up","yes"]
["chr3",69169990,69386073,"FRMD4B",0.28,1.75,6.31,2.66,0.01,"up","yes"]
["chr17",7484366,7514616,"POLR2A",4.52,27.29,6.04,2.6,0.01,"up","yes"]
["chr10",69087280,69104818,"SRGN",49.45,298.54,6.04,2.59,0.01,"up","yes"]
["chr17",17476986,17493226,"MED9",0.43,2.78,6.45,2.69,0.01,"up","yes"]
["chr12",53452311,53475553,"PCBP2",1.42,8.76,6.17,2.63,0.01,"up","yes"]
["chr17",40062899,40092627,"THRA",0.23,1.43,6.3,2.65,0.01,"up","yes"]
["chr11",59144779,59155036,"FAM111A",0.44,2.76,6.22,2.64,0.01,"up","yes"]
["chr1",113929710,113977804,"HIPK1",3.61,21.57,5.98,2.58,0.01,"up","yes"]
["chr8",102253736,102412689,"UBR5",0.19,1.15,6.18,2.63,0.01,"up","yes"]
["chr3",119294373,119420714,"ARHGAP31",0.38,2.3,6.07,2.6,0.01,"up","yes"]
["chr17",64499342,64503823,"DDX5",0.33,2.09,6.37,2.67,0.01,"up","yes"]
["chrX",152917865,152973480,"ZNF185",0.5,3.05,6.15,2.62,0.01,"up","yes"]
["chrX",18507097,18638407,"CDKL5",0.18,1.12,6.09,2.61,0.01,"up","yes"]
["chr2",113236237,113267010,"PAX8-AS1",0.46,2.87,6.22,2.64,0.01,"up","yes"]
["chr15",44573357,44663678,"SPG11",0.34,2.08,6.09,2.61,0.01,"up","yes"]
["chr1",11012400,11026420,"TARDBP",1.46,8.7,5.96,2.58,0.01,"up","yes"]
["chr13",77044655,77326679,"MYCBP2",1.52,8.98,5.92,2.56,0.01,"up","yes"]
["chr7",36854361,37449249,"ELMO1",2.19,13,5.94,2.57,0.01,"up","yes"]
["chr16",57668317,57689378,"ADGRG3",2.66,15.83,5.95,2.57,0.01,"up","yes"]
["chr9",35696893,35728557,"TLN1",1.74,10.25,5.91,2.56,0.01,"up","yes"]
["chr5",88722601,88883375,"MEF2C",1.64,9.85,5.99,2.58,0.01,"up","yes"]
["chr16",85801,138670,"NPRL3",0.51,3.16,6.14,2.62,0.01,"up","yes"]
["chr8",141207173,141308153,"SLC45A4",1.86,10.96,5.9,2.56,0.01,"up","yes"]
["chr16",89267630,89490561,"ANKRD11",1.28,7.56,5.9,2.56,0.01,"up","yes"]
["chr20",56412261,56460387,"CASS4",0.39,2.44,6.19,2.63,0.01,"up","yes"]
["chr6",45422485,45551079,"RUNX2",0.8,4.76,5.95,2.57,0.01,"up","yes"]
["chr7",2234291,2242198,"MRM2",0.67,4.17,6.22,2.64,0.01,"up","yes"]
["chr11",63681446,63759882,"RTN3",0.49,3.01,6.14,2.62,0.01,"up","yes"]
["chr4",108047765,108166988,"LEF1",1.48,8.83,5.96,2.58,0.01,"up","yes"]
["chr5",177483422,177497646,"PDLIM7",0.97,5.85,6.02,2.59,0.01,"up","yes"]
["chrX",77505713,77786216,"ATRX",0.45,2.69,5.9,2.56,0.02,"up","yes"]
["chr7",100205357,100221488,"STAG3",0.28,1.73,6.24,2.64,0.02,"up","yes"]
["chr7",74209396,74229834,"LAT2",3.83,22.38,5.85,2.55,0.02,"up","yes"]
["chr14",65075126,65102248,"MAX",4.9,28.64,5.84,2.55,0.02,"up","yes"]
["chr2",239048169,239400949,"HDAC4",0.82,4.79,5.86,2.55,0.02,"up","yes"]
["chr2",229767441,229921999,"TRIP12",1.61,9.4,5.83,2.54,0.02,"up","yes"]
["chr16",9092191,9113181,"C16orf72",2.36,13.71,5.8,2.54,0.02,"up","yes"]
["chr16",67109963,67147131,"C16orf70",0.73,4.51,6.17,2.62,0.02,"up","yes"]
["chr5",43289395,43313493,"HMGCS1",0.6,3.54,5.92,2.57,0.02,"up","yes"]
["chr19",52527653,52556336,"ZNF808",0.39,2.36,6.04,2.6,0.02,"up","yes"]
["chr14",68787662,68793240,"ZFP36L1",19.07,110,5.77,2.53,0.02,"up","yes"]
["chr1",28887091,29120046,"EPB41",0.22,1.33,6.01,2.59,0.02,"up","yes"]
["chr3",25597905,25664372,"TOP2B",0.56,3.26,5.86,2.55,0.02,"up","yes"]
["chr17",80260868,80398786,"RNF213",3.88,22.26,5.74,2.52,0.02,"up","yes"]
["chr11",85957688,86069097,"PICALM",0.23,1.38,6.09,2.61,0.02,"up","yes"]
["chr6",159682165,159693278,"SOD2",17.66,101.15,5.73,2.52,0.02,"up","yes"]
["chrX",109536876,109544690,"NXT2",0.46,2.75,6.02,2.59,0.02,"up","yes"]
["chr9",136494444,136545862,"NOTCH1",5.48,31.27,5.71,2.51,0.02,"up","yes"]
["chr4",1721519,1738350,"TACC3",0.84,4.88,5.84,2.55,0.02,"up","yes"]
["chr19",54449190,54461964,"LENG8",1.55,8.87,5.74,2.52,0.02,"up","yes"]
["chr12",120534812,120576886,"RNF10",8.99,51.15,5.69,2.51,0.02,"up","yes"]
["chr2",88846693,88866183,"AC244205.1",5.97,34.13,5.72,2.52,0.02,"up","yes"]
["chr20",38472816,38578859,"RALGAPB",0.86,4.92,5.71,2.51,0.02,"up","yes"]
["chr3",64010554,64017732,"PSMD6",0.2,1.23,6.03,2.59,0.02,"up","yes"]
["chr15",40287909,40307837,"PLCB2",0.92,5.26,5.74,2.52,0.02,"up","yes"]
["chr9",137078141,137084539,"UAP1L1",0.44,2.61,5.9,2.56,0.02,"up","yes"]
["chr5",139293778,139330441,"MATR3",0.42,2.47,5.83,2.54,0.02,"up","yes"]
["chr15",40441187,40468228,"BAHD1",0.72,4.16,5.75,2.52,0.02,"up","yes"]
["chr1",198639095,198757283,"PTPRC",36.82,207.13,5.63,2.49,0.02,"up","yes"]
["chr12",57128499,57213351,"LRP1",1.83,10.33,5.63,2.49,0.02,"up","yes"]
["chr7",128640482,128652334,"AC018638.4",1.39,7.98,5.73,2.52,0.02,"up","yes"]
["chr6",75601509,75715904,"SENP6",0.9,5.1,5.67,2.5,0.02,"up","yes"]
["chr15",34233259,34336844,"SLC12A6",3.3,18.45,5.6,2.49,0.02,"up","yes"]
["chr1",173938411,173993072,"RC3H1",0.83,4.72,5.68,2.51,0.02,"up","yes"]
["chr4",122152333,122362752,"KIAA1109",1.02,5.69,5.59,2.48,0.02,"up","yes"]
["chr12",752576,912051,"WNK1",1.16,6.5,5.58,2.48,0.02,"up","yes"]
["chr12",50505107,50748667,"DIP2B",2.13,11.85,5.57,2.48,0.02,"up","yes"]
["chr9",125261832,125367207,"GAPVD1",0.54,3.05,5.61,2.49,0.02,"up","yes"]
["chr1",16625375,16644672,"CROCCP2",0.52,3.03,5.86,2.55,0.02,"up","yes"]
["chr16",66604243,66613880,"CMTM3",2.75,15.29,5.57,2.48,0.02,"up","yes"]
["chr6",43477573,43506553,"TJAP1",0.53,3.07,5.78,2.53,0.02,"up","yes"]
["chr12",752576,912051,"WNK1",0.51,2.85,5.55,2.47,0.02,"up","yes"]
["chr16",69118010,69132570,"CHTF8",2.12,11.77,5.55,2.47,0.02,"up","yes"]
["chr12",120446438,120463749,"GATC",0.58,3.25,5.63,2.49,0.02,"up","yes"]
["chr1",161541734,161631962,"FCGR3B",2.26,12.54,5.55,2.47,0.02,"up","yes"]
["chr9",121075012,121177608,"CNTRL",0.98,5.43,5.52,2.46,0.02,"up","yes"]
["chr6",125781161,125931111,"NCOA7",0.19,1.1,5.72,2.52,0.02,"up","yes"]
["chr1",155336055,155562532,"ASH1L",1.25,6.84,5.47,2.45,0.02,"up","yes"]
["chr2",130181928,130190727,"MZT2B",2.57,14.3,5.57,2.48,0.02,"up","yes"]
["chr5",139293963,139330437,"MATR3",0.47,2.63,5.61,2.49,0.02,"up","yes"]
["chr4",183444591,183448198,"CDKN2AIP",0.55,3.14,5.67,2.5,0.02,"up","yes"]
["chr2",159768630,159798255,"CD302",0.71,3.94,5.57,2.48,0.02,"up","yes"]
["chr1",10210805,10308597,"KIF1B",0.29,1.63,5.59,2.48,0.02,"up","yes"]
["chr19",38930999,38933020,"MRPS12",0.87,5.01,5.76,2.53,0.02,"up","yes"]
["chr19",2164149,2232578,"DOT1L",0.46,2.51,5.51,2.46,0.02,"up","yes"]
["chr8",142727203,142736927,"THEM6",0.44,2.52,5.75,2.52,0.02,"up","yes"]
["chr14",22900777,22919178,"RBM23",0.35,2,5.77,2.53,0.02,"up","yes"]
["chr6",24839359,24877355,"RIPOR2",1.17,6.46,5.51,2.46,0.02,"up","yes"]
["chr18",12991362,13125036,"CEP192",0.29,1.63,5.53,2.47,0.02,"up","yes"]
["chr7",5313035,5397326,"TNRC18",1.84,9.96,5.41,2.44,0.02,"up","yes"]
["chr1",153728067,153774808,"INTS3",0.69,3.77,5.48,2.45,0.02,"up","yes"]
["chr5",132488671,132490754,"IRF1",0.82,4.71,5.77,2.53,0.02,"up","yes"]
["chr7",5306800,5423546,"TNRC18",0.47,2.54,5.44,2.44,0.02,"up","yes"]
["chr19",35000323,35026469,"GRAMD1A",0.69,3.85,5.56,2.47,0.02,"up","yes"]
["chr19",1426349,1435684,"DAZAP1",0.4,2.24,5.57,2.48,0.02,"up","yes"]
["chr17",48048773,48061480,"NFE2L1",0.65,3.55,5.47,2.45,0.02,"up","yes"]
["chr15",34233259,34336844,"SLC12A6",0.24,1.37,5.65,2.5,0.02,"up","yes"]
["chr2",73986404,74108176,"TET3",1.35,7.27,5.37,2.42,0.02,"up","yes"]
["chr2",174560770,174682899,"WIPF1",0.56,3.11,5.55,2.47,0.02,"up","yes"]
["chr22",19846138,19854896,"RTL10",0.37,2.03,5.5,2.46,0.02,"up","yes"]
["chr19",17824786,17848032,"JAK3",2.42,12.94,5.35,2.42,0.02,"up","yes"]
["chr2",128091311,128195677,"UGGT1",0.77,4.13,5.37,2.42,0.02,"up","yes"]
["chr8",38269697,38382272,"NSD3",0.76,4.06,5.37,2.43,0.02,"up","yes"]
["chr4",8199371,8241091,"SH3TC1",0.25,1.41,5.62,2.49,0.02,"up","yes"]
["chr19",39391323,39400561,"MED29",0.7,3.82,5.45,2.45,0.02,"up","yes"]
["chr19",39391311,39400637,"MED29",0.68,3.72,5.45,2.45,0.02,"up","yes"]
["chr8",132775384,132848807,"PHF20L1",0.3,1.61,5.47,2.45,0.02,"up","yes"]
["chr22",38734688,38755956,"SUN2",7.1,37.76,5.32,2.41,0.02,"up","yes"]
["chr9",134326580,134437019,"RXRA",5.83,31.07,5.33,2.41,0.02,"up","yes"]
["chr17",19648723,19676117,"ALDH3A2",0.4,2.23,5.58,2.48,0.02,"up","yes"]
["chr14",75278774,75282230,"FOS",8.39,44.39,5.29,2.4,0.02,"up","yes"]
["chr16",68264548,68301819,"SLC7A6",0.55,2.96,5.37,2.43,0.02,"up","yes"]
["chr7",93131033,93148345,"SAMD9L",0.23,1.25,5.48,2.45,0.03,"up","yes"]
["chr5",150357666,150400292,"TCOF1",0.23,1.3,5.59,2.48,0.03,"up","yes"]
["chr3",114056735,114088349,"QTRT2",0.47,2.54,5.43,2.44,0.03,"up","yes"]
["chr7",150514830,150521073,"GIMAP7",1.11,6.1,5.51,2.46,0.03,"up","yes"]
["chr6",152122605,152185411,"SYNE1",0.53,2.86,5.44,2.44,0.03,"up","yes"]
["chr14",95086228,95157422,"DICER1",2,10.49,5.25,2.39,0.03,"up","yes"]
["chr14",58244847,58271275,"PSMA3",1.19,6.42,5.39,2.43,0.03,"up","yes"]
["chr13",37009386,37059695,"SUPT20H",1.18,6.31,5.33,2.41,0.03,"up","yes"]
["chr3",101325867,101513223,"SENP7",0.5,2.67,5.38,2.43,0.03,"up","yes"]
["chr11",121608200,121621240,"SORL1",0.99,5.2,5.28,2.4,0.03,"up","yes"]
["chr8",58411371,58451986,"UBXN2B",1.36,7.11,5.24,2.39,0.03,"up","yes"]
["chr17",2384060,2401118,"MNT",0.91,4.8,5.27,2.4,0.03,"up","yes"]
["chr15",78264574,78282192,"DNAJA4",0.29,1.59,5.55,2.47,0.03,"up","yes"]
["chr18",79679846,79754503,"CTDP1",1.03,5.42,5.28,2.4,0.03,"up","yes"]
["chr19",42230190,42241893,"GSK3A",1.4,7.35,5.25,2.39,0.03,"up","yes"]
["chr12",132507030,132511952,"FBRSL1",0.7,3.72,5.34,2.42,0.03,"up","yes"]
["chr3",51671175,51704322,"TEX264",0.5,2.82,5.58,2.48,0.03,"up","yes"]
["chr14",91780955,91836447,"TC2N",0.69,3.67,5.28,2.4,0.03,"up","yes"]
["chr19",42284640,42295534,"CIC",0.57,3,5.29,2.4,0.03,"up","yes"]
["chr12",752576,909436,"WNK1",1.74,9.04,5.19,2.38,0.03,"up","yes"]
["chr6",81745730,81752708,"FAM46A",0.87,4.57,5.23,2.39,0.03,"up","yes"]
["chr1",207752057,207795513,"CD46",1.21,6.35,5.24,2.39,0.03,"up","yes"]
["chr3",12900849,13073117,"IQSEC1",1.05,5.52,5.23,2.39,0.03,"up","yes"]
["chr11",18468986,18527232,"TSG101",0.87,4.65,5.36,2.42,0.03,"up","yes"]
["chrX",149502660,149505280,"IDS",0.72,3.99,5.52,2.46,0.03,"up","yes"]
["chr2",168455862,168775137,"CERS6",0.74,3.86,5.19,2.38,0.03,"up","yes"]
["chr22",29268009,29300524,"EWSR1",0.44,2.42,5.43,2.44,0.03,"up","yes"]
["chr19",41860257,41871416,"RPS19",15.65,81.08,5.18,2.37,0.03,"up","yes"]
["chr19",34172658,34219877,"LSM14A",1.12,6.05,5.42,2.44,0.03,"up","yes"]
["chr4",39045060,39122208,"KLHL5",0.43,2.29,5.37,2.42,0.03,"up","yes"]
["chr11",64769278,64770639,"SF1",1.39,7.57,5.43,2.44,0.03,"up","yes"]
["chr20",32192503,32207791,"PLAGL2",1.41,7.28,5.14,2.36,0.03,"up","yes"]
["chr12",111405948,111451623,"SH2B3",3.59,18.34,5.11,2.35,0.03,"up","yes"]
["chr7",98106885,98209633,"LMTK2",1.04,5.32,5.13,2.36,0.03,"up","yes"]
["chr11",47270156,47330030,"MADD",1.07,5.54,5.15,2.37,0.03,"up","yes"]
["chr2",237692216,237765915,"LRRFIP1",1.78,9.15,5.13,2.36,0.03,"up","yes"]
["chr17",80260866,80395312,"RNF213",0.83,4.23,5.11,2.35,0.03,"up","yes"]
["chr1",156463727,156500828,"MEF2D",0.29,1.54,5.26,2.4,0.03,"up","yes"]
["chr14",99169287,99271228,"BCL11B",0.86,4.39,5.12,2.36,0.03,"up","yes"]
["chr7",101085439,101097967,"TRIM56",1.13,5.77,5.09,2.35,0.03,"up","yes"]
["chr5",179911651,180071721,"RNF130",0.29,1.51,5.17,2.37,0.03,"up","yes"]
["chr6",7107808,7251980,"RREB1",0.27,1.42,5.19,2.38,0.03,"up","yes"]
["chr3",43286540,43351138,"SNRK",2.67,13.56,5.08,2.34,0.03,"up","yes"]
["chr12",112160190,112382439,"HECTD4",0.6,3.07,5.09,2.35,0.03,"up","yes"]
["chr7",91940867,92110673,"AKAP9",0.72,3.67,5.09,2.35,0.03,"up","yes"]
["chr17",67070438,67245183,"HELZ",1.21,6.15,5.07,2.34,0.03,"up","yes"]
["chr1",2228695,2310119,"SKI",1.55,7.89,5.08,2.35,0.03,"up","yes"]
["chr1",235166895,235328219,"ARID4B",0.21,1.1,5.31,2.41,0.03,"up","yes"]
["chr2",85324385,85327985,"TGOLN2",0.77,4.03,5.25,2.39,0.03,"up","yes"]
["chr12",47773208,47782753,"SLC48A1",0.54,2.85,5.25,2.39,0.03,"up","yes"]
["chr17",44187272,44191711,"TMUB2",0.38,2.07,5.4,2.43,0.03,"up","yes"]
["chr7",50304054,50405097,"IKZF1",0.47,2.41,5.15,2.36,0.03,"up","yes"]
["chr6",149317658,149411611,"TAB2",3.27,16.53,5.05,2.34,0.03,"up","yes"]
["chr11",118747763,118790967,"DDX6",2.15,10.87,5.05,2.34,0.03,"up","yes"]
["chr1",154220914,154271478,"UBAP2L",2.11,10.67,5.05,2.34,0.03,"up","yes"]
["chr3",113648385,113696646,"USF3",0.74,3.71,5.04,2.33,0.03,"up","yes"]
["chr8",23541687,23566378,"SLC25A37",2.31,12.16,5.27,2.4,0.03,"up","yes"]
["chr9",129094810,129110804,"CRAT",0.8,4.13,5.16,2.37,0.03,"up","yes"]
["chr1",244842916,244864537,"HNRNPU",0.77,3.89,5.02,2.33,0.03,"up","yes"]
["chr2",85318020,85328296,"TGOLN2",0.43,2.2,5.1,2.35,0.03,"up","yes"]
["chr1",25543580,25568886,"LDLRAP1",5.02,25.14,5.01,2.32,0.03,"up","yes"]
["chr19",5993164,6110534,"RFX2",1.33,6.7,5.05,2.34,0.03,"up","yes"]
["chr14",74670642,74713067,"AREL1",0.5,2.6,5.21,2.38,0.03,"up","yes"]
["chr2",105851782,105894272,"NCK2",0.41,2.13,5.26,2.4,0.03,"up","yes"]
["chr13",102799049,102841533,"BIVM",0.29,1.5,5.2,2.38,0.03,"up","yes"]
["chr1",174964281,174991823,"RABGAP1L",0.8,4.07,5.1,2.35,0.03,"up","yes"]
["chr14",103629227,103686917,"KLC1",0.41,2.13,5.2,2.38,0.03,"up","yes"]
["chr5",138338032,138349729,"FAM53C",4.4,21.96,4.99,2.32,0.03,"up","yes"]
["chr19",49335400,49340606,"CD37",35.18,175.07,4.98,2.31,0.03,"up","yes"]
["chr1",154582067,154627964,"ADAR",0.31,1.59,5.12,2.36,0.03,"up","yes"]
["chr7",26291923,26374325,"SNX10",6.47,32.17,4.97,2.31,0.03,"up","yes"]
["chr9",114336127,114387963,"AKNA",6.6,32.77,4.97,2.31,0.03,"up","yes"]
["chr17",17158497,17185560,"MPRIP",0.66,3.33,5.03,2.33,0.03,"up","yes"]
["chr11",126283087,126294933,"TIRAP",0.77,3.95,5.12,2.36,0.03,"up","yes"]
["chr17",63622442,63696303,"MAP3K3",1.35,6.76,4.99,2.32,0.03,"up","yes"]
["chr14",91458008,91509763,"PPP4R3A",1.37,6.82,5,2.32,0.03,"up","yes"]
["chr19",4047742,4065732,"ZBTB7A",1.24,6.25,5.05,2.34,0.03,"up","yes"]
["chr22",26657520,26676475,"MIAT",0.31,1.54,5.02,2.33,0.03,"up","yes"]
["chr17",45221463,45247280,"FMNL1",4.63,22.87,4.94,2.3,0.03,"up","yes"]
["chr5",141515016,141619055,"DIAPH1",5.75,28.35,4.93,2.3,0.03,"up","yes"]
["chr15",70050097,70096798,"TLE3",3.57,17.68,4.95,2.31,0.03,"up","yes"]
["chr11",63681500,63759885,"RTN3",14.23,69.99,4.92,2.3,0.03,"up","yes"]
["chr12",122078722,122147347,"MLXIP",1.66,8.2,4.93,2.3,0.03,"up","yes"]
["chr2",196987488,197310666,"ANKRD44",0.85,4.22,4.97,2.31,0.03,"up","yes"]
["chr2",121337776,121649476,"CLASP1",1.15,5.66,4.93,2.3,0.03,"up","yes"]
["chr4",105146886,105242762,"TET2",0.27,1.39,5.09,2.35,0.03,"up","yes"]
["chrX",96684712,97604997,"DIAPH2",0.3,1.48,5.02,2.33,0.04,"up","yes"]
["chr8",18055992,18084370,"ASAH1",4.45,21.85,4.91,2.3,0.04,"up","yes"]
["chr2",219219382,219229368,"ATG9A",0.7,3.49,5,2.32,0.04,"up","yes"]
["chr13",112690329,112887168,"ATP11A",0.47,2.3,4.95,2.31,0.04,"up","yes"]
["chr14",75278977,75280789,"FOS",2.84,14.3,5.03,2.33,0.04,"up","yes"]
["chr11",118893874,118925618,"BCL9L",2.08,10.14,4.88,2.29,0.04,"up","yes"]
["chr9",131125586,131234663,"NUP214",0.26,1.29,5.03,2.33,0.04,"up","yes"]
["chr6",158312488,158511828,"TULP4",0.3,1.48,4.94,2.3,0.04,"up","yes"]
["chr2",96274731,96284723,"SNRNP200",0.46,2.33,5.1,2.35,0.04,"up","yes"]
["chrX",118727572,118794539,"IL13RA1",7.58,36.79,4.85,2.28,0.04,"up","yes"]
["chr12",14385064,14498763,"ATF7IP",0.2,1.03,5.12,2.36,0.04,"up","yes"]
["chr3",71675416,71725375,"EIF4E3",1.19,5.81,4.87,2.28,0.04,"up","yes"]
["chr12",54497758,54542773,"NCKAP1L",0.26,1.33,5.14,2.36,0.04,"up","yes"]
["chr17",4715589,4721138,"ARRB2",1.33,6.62,4.97,2.31,0.04,"up","yes"]
["chr17",16126107,16215529,"NCOR1",0.55,2.84,5.13,2.36,0.04,"up","yes"]
["chr16",57999546,58020542,"USB1",0.68,3.55,5.21,2.38,0.04,"up","yes"]
["chr3",198153287,198170059,"FAM157A",1.04,5.27,5.08,2.34,0.04,"up","yes"]
["chr8",140511298,140517137,"CHRAC1",1.67,8.17,4.9,2.29,0.04,"up","yes"]
["chr2",60457198,60553498,"BCL11A",0.22,1.11,5.03,2.33,0.04,"up","yes"]
["chr11",2902193,2925246,"SLC22A18",0.84,4.23,5.02,2.33,0.04,"up","yes"]
["chr11",60971866,61019321,"CD6",0.48,2.45,5.15,2.37,0.04,"up","yes"]
["chr4",39062232,39121205,"KLHL5",0.78,3.86,4.94,2.31,0.04,"up","yes"]
["chr1",52423275,52553100,"ZCCHC11",0.7,3.41,4.89,2.29,0.04,"up","yes"]
["chr3",126461083,126475865,"ZXDC",0.8,3.95,4.96,2.31,0.04,"up","yes"]
["chr8",133047105,133074959,"SLA",0.67,3.46,5.16,2.37,0.04,"up","yes"]
["chr3",14402576,14489349,"SLC6A6",4.7,22.73,4.83,2.27,0.04,"up","yes"]
["chr6",78935867,79078236,"PHIP",1.5,7.27,4.84,2.27,0.04,"up","yes"]
["chr17",42702385,42745031,"EZH1",0.49,2.5,5.06,2.34,0.04,"up","yes"]
["chr19",57527393,57540876,"ZNF549",0.35,1.76,5.02,2.33,0.04,"up","yes"]
["chr7",137874979,138002057,"CREB3L2",1.03,4.99,4.84,2.28,0.04,"up","yes"]
["chr15",64499292,64686068,"ZNF609",0.6,2.93,4.86,2.28,0.04,"up","yes"]
["chr20",50282558,50284859,".",0.56,2.81,5.01,2.32,0.04,"up","yes"]
["chr12",115953872,116277338,"MED13L",2.93,14.07,4.8,2.26,0.04,"up","yes"]
["chr15",98648971,98964530,"IGF1R",0.97,4.66,4.81,2.27,0.04,"up","yes"]
["chr5",83471465,83582303,"VCAN",0.57,2.76,4.83,2.27,0.04,"up","yes"]
["chr12",113221460,113298585,"TPCN1",0.39,1.94,4.9,2.29,0.04,"up","yes"]
["chr19",2070988,2096508,"MOB3A",7.68,36.86,4.8,2.26,0.04,"up","yes"]
["chr7",142626649,142627399,"TRBV20-1",3.22,16.12,5.01,2.32,0.04,"up","yes"]
["chr16",88453317,88537016,"ZFPM1",0.24,1.18,4.98,2.31,0.04,"up","yes"]
["chr4",82352498,82373956,"HNRNPD",1.27,6.18,4.86,2.28,0.04,"up","yes"]
["chr5",176526697,176537420,"RNF44",0.23,1.15,5.1,2.35,0.04,"up","yes"]
["chr15",92900320,93028005,"CHD2",3.08,14.74,4.79,2.26,0.04,"up","yes"]
["chr19",1415970,1435687,"DAZAP1",0.25,1.3,5.17,2.37,0.04,"up","yes"]
["chr11",85957684,86069059,"PICALM",7.95,38.05,4.79,2.26,0.04,"up","yes"]
["chr1",212992182,213015826,"ANGEL2",0.24,1.23,5.01,2.33,0.04,"up","yes"]
["chr11",65497762,65506469,"MALAT1",4.29,20.47,4.77,2.25,0.04,"up","yes"]
["chr17",40122584,40134810,"MSL1",0.79,3.87,4.92,2.3,0.04,"up","yes"]
["chr6",34279679,34392674,"NUDT3",2.05,9.77,4.77,2.25,0.04,"up","yes"]
["chr5",96662352,96774694,"CAST",5.75,27.39,4.76,2.25,0.04,"up","yes"]
["chr8",30095398,30108524,"LEPROTL1",4.23,20.19,4.77,2.25,0.04,"up","yes"]
["chr4",38794694,38846083,"TLR1",0.8,3.84,4.79,2.26,0.04,"up","yes"]
["chr19",1248553,1259140,"MIDN",6.31,29.96,4.75,2.25,0.04,"up","yes"]
["chr16",17101769,17470881,"XYLT1",0.76,3.64,4.77,2.25,0.04,"up","yes"]
["chr17",67947754,67981762,"BPTF",0.5,2.53,5.07,2.34,0.04,"up","yes"]
["chr6",33291654,33314387,"RGL2",6.61,31.36,4.74,2.24,0.04,"up","yes"]
["chr12",71839759,71923362,"TBC1D15",0.48,2.4,5.01,2.33,0.04,"up","yes"]
["chr18",75210755,75289950,"TSHZ1",0.31,1.51,4.89,2.29,0.04,"up","yes"]
["chr1",222712553,222735196,"BROX",0.61,2.95,4.82,2.27,0.04,"up","yes"]
["chr15",75206444,75209595,"C15orf39",0.65,3.16,4.85,2.28,0.04,"up","yes"]
["chr16",23641392,23677455,"DCTN5",0.52,2.46,4.76,2.25,0.04,"up","yes"]
["chr7",139829247,140020291,"TBXAS1",0.54,2.65,4.93,2.3,0.04,"up","yes"]
["chr12",54369136,54384723,"ZNF385A",2.98,14.08,4.73,2.24,0.04,"up","yes"]
["chr2",63893056,64019072,"VPS54",0.64,3.1,4.81,2.27,0.04,"up","yes"]
["chr17",44397416,44503401,"GPATCH8",0.41,2,4.84,2.27,0.04,"up","yes"]
["chr1",27612300,27624062,"FGR",0.4,1.97,4.97,2.31,0.04,"up","yes"]
["chr19",54593582,54605457,"LILRA1",2.64,12.37,4.69,2.23,0.04,"up","yes"]
["chr14",89161385,89417112,"FOXN3",0.37,1.84,4.95,2.31,0.04,"up","yes"]
["chr7",73293497,73301161,"POM121B",0.7,3.34,4.81,2.26,0.04,"up","yes"]
["chr6",15248855,15522040,"JARID2",0.5,2.4,4.76,2.25,0.04,"up","yes"]
["chr4",10074340,10116949,"WDR1",1.27,6.01,4.73,2.24,0.04,"up","yes"]
["chrX",53532096,53684169,"HUWE1",2.12,9.9,4.66,2.22,0.04,"up","yes"]
["chr17",29625938,29761464,"SSH2",9.59,44.6,4.65,2.22,0.04,"up","yes"]
["chr12",53665183,53676398,"ATP5G2",3.7,17.58,4.75,2.25,0.04,"up","yes"]
["chr7",152134925,152436005,"KMT2C",0.59,2.76,4.67,2.22,0.04,"up","yes"]
["chr16",28494649,28498970,"APOBR",9.91,45.99,4.64,2.22,0.05,"up","yes"]
["chr14",95417494,95475836,"SYNE3",0.27,1.35,4.97,2.31,0.05,"up","yes"]
["chr19",49512279,49526333,"FCGRT",7.86,36.55,4.65,2.22,0.05,"up","yes"]
["chr16",22437401,22491826,"SMG1P1",0.49,2.34,4.76,2.25,0.05,"up","yes"]
["chr10",84328663,84518517,"CCSER2",0.29,1.36,4.75,2.25,0.05,"up","yes"]
["chr5",138337511,138346972,"FAM53C",0.63,3.08,4.85,2.28,0.05,"up","yes"]
["chr15",52307283,52529050,"MYO5A",0.43,2.03,4.67,2.22,0.05,"up","yes"]
["chr7",105014208,105112810,"KMT2E",2.8,12.97,4.64,2.21,0.05,"up","yes"]
["chr7",4682309,4771443,"FOXK1",0.67,3.13,4.65,2.22,0.05,"up","yes"]
["chr9",97600083,97633575,"TSTD2",0.43,2.06,4.74,2.25,0.05,"up","yes"]
["chr17",77450737,77500594,"9-Sep",0.55,2.63,4.78,2.26,0.05,"up","yes"]
["chr17",7312659,7329328,"NEURL4",0.68,3.18,4.67,2.22,0.05,"up","yes"]
["chr7",139231485,139308236,"UBN2",0.4,1.88,4.65,2.22,0.05,"up","yes"]
["chr11",45804406,45813015,"SLC35C1",0.59,2.77,4.73,2.24,0.05,"up","yes"]
["chr12",56316936,56334053,"PAN2",0.32,1.55,4.78,2.26,0.05,"up","yes"]
["chrX",23785260,23786210,"SAT1",2.51,11.89,4.74,2.24,0.05,"up","yes"]
["chr4",13568810,13627712,"BOD1L1",2.41,11.1,4.61,2.2,0.05,"up","yes"]
["chr19",12701153,12722572,"TNPO2",0.47,2.24,4.79,2.26,0.05,"up","yes"]
["chr17",49289208,49361993,"ZNF652",0.3,1.43,4.8,2.26,0.05,"up","yes"]
["chr8",141128621,141195796,"DENND3",0.23,1.12,4.8,2.26,0.05,"up","yes"]
["chr6",89329659,89352848,"UBE2J1",0.91,4.44,4.86,2.28,0.05,"up","yes"]
["chr2",230416207,230545606,"SP100",2.74,12.62,4.61,2.2,0.05,"up","yes"]
["chr1",147541412,147626216,"BCL9",0.42,1.95,4.67,2.22,0.05,"up","yes"]
["chr18",13620868,13652754,"LDLRAD4",0.28,1.31,4.72,2.24,0.05,"up","yes"]
["chr2",215312091,215349763,"ATIC",0.92,4.33,4.69,2.23,0.05,"up","yes"]
["chr8",94510733,94553529,"VIRMA",0.85,3.94,4.67,2.22,0.05,"up","yes"]
["chr10",45454593,45594906,"8-Mar",2.58,11.82,4.59,2.2,0.05,"up","yes"]
["chr17",39406601,39451286,"MED1",0.62,2.89,4.64,2.21,0.05,"up","yes"]
["chr7",92447453,92458836,"GATAD1",0.54,2.53,4.72,2.24,0.05,"up","yes"]
["chr11",65772853,65780656,"AP5B1",0.86,3.97,4.63,2.21,0.05,"up","yes"]
["chr12",121804738,121830239,"SETD1B",1.44,6.61,4.59,2.2,0.05,"up","yes"]
["chr14",75016989,75049691,"MLH3",0.33,1.55,4.74,2.25,0.05,"up","yes"]
["chr1",51789191,51878805,"NRDC",0.97,4.49,4.62,2.21,0.05,"up","yes"]
["chr17",42700431,42745054,"EZH1",0.75,3.46,4.62,2.21,0.05,"up","yes"]
["chr17",36194869,36196747,"CCL3L3",0.93,4.36,4.71,2.24,0.05,"up","yes"]
["chr2",218382248,218395323,"SLC11A1",2.23,10.28,4.6,2.2,0.05,"up","yes"]
["chr6",3076824,3115187,"RIPK1",0.3,1.43,4.76,2.25,0.05,"up","yes"]
["chr19",1107636,1174283,"SBNO2",4.42,20.09,4.54,2.18,0.05,"up","yes"]
["chr1",209768060,209782320,"TRAF3IP3",0.99,4.59,4.63,2.21,0.05,"up","yes"]
["chr6",42929200,42939287,"CNPY3",7.43,33.82,4.55,2.19,0.05,"up","yes"]
["chr12",57096365,57111374,"STAT6",2.01,9.17,4.57,2.19,0.05,"up","yes"]
["chr6",31723373,31726714,"MPIG6B",2.82,12.86,4.56,2.19,0.05,"up","yes"]
["chr19",32406125,32485889,"DPY19L3",0.39,1.79,4.62,2.21,0.05,"up","yes"]
["chr5",134115352,134147983,"TCF7",0.54,2.48,4.6,2.2,0.05,"up","yes"]
["chr3",97822040,97944963,"CRYBG3",0.28,1.29,4.61,2.2,0.05,"up","yes"]
["chr9",92210207,92293700,"IARS",0.77,3.53,4.59,2.2,0.05,"up","yes"]
["chrMT",2024,15531,"MT-ND6",11.64,53.04,4.56,2.19,0.05,"up","yes"]
["chr11",72685588,72722028,"ARAP1",1.53,6.98,4.56,2.19,0.05,"up","yes"]
["chr10",110871791,110898127,"PDCD4",5.28,23.96,4.54,2.18,0.05,"up","yes"]
["chr3",171063881,171460063,"TNIK",0.74,3.44,4.61,2.21,0.05,"up","yes"]
["chr3",134486254,134561895,"CEP63",0.45,2.11,4.71,2.24,0.05,"up","yes"]
["chr7",133034607,133035920,"AC008038.1",13.5,60.79,4.5,2.17,0.05,"up","yes"]
["chr9",121339077,121370205,"STOM",5.69,25.63,4.5,2.17,0.05,"up","yes"]
["chr7",66114605,66154561,"CRCP",0.72,3.33,4.61,2.2,0.05,"up","yes"]
["chr12",122272043,122422632,"CLIP1",1.15,5.21,4.54,2.18,0.05,"up","yes"]
["chr22",31496563,31618586,"SFI1",1.06,4.81,4.55,2.18,0.05,"up","yes"]
["chr7",5480558,5513798,"FBXL18",0.25,1.19,4.78,2.26,0.05,"up","yes"]
["chr13",32031300,32299122,"FRY",1.25,5.6,4.48,2.16,0.05,"up","yes"]
["chr4",94451902,94668223,"PDLIM5",1.25,5.65,4.51,2.17,0.05,"up","yes"]
["chr11",46677080,46700599,"ARHGAP1",4.93,21.99,4.46,2.16,0.05,"up","yes"]
["chr11",64894546,64917248,"ATG2A",1.79,8.02,4.47,2.16,0.05,"up","yes"]
["chr19",13099028,13102836,"LYL1",3.07,13.82,4.5,2.17,0.05,"up","yes"]
["chrX",80670854,80809688,"BRWD3",1.43,6.35,4.46,2.16,0.05,"up","yes"]
["chr11",46617541,46673041,"ATG13",0.84,3.84,4.57,2.19,0.05,"up","yes"]
["chr1",29147743,29181987,"SRSF4",6.09,27.09,4.45,2.15,0.05,"up","yes"]
["chr17",42998477,43002932,"RPL27",350.63,1.83,0.01,-7.58,0,"down","yes"]
["chr13",46125920,46203222,"LCP1",87.88,0.54,0.01,-7.36,0,"down","yes"]
["chr1",28147166,28177188,"PTAFR",39.89,0.27,0.01,-7.23,0,"down","yes"]
["chr2",88857160,89143159,"AC244205.1",96.02,0.81,0.01,-6.89,0,"down","yes"]
["chr12",10371395,10409769,"KLRC4-KLRK1",23.61,0.32,0.01,-6.18,0,"down","yes"]
["chr1",110871180,110899960,"CD53",84.02,1.25,0.01,-6.07,0,"down","yes"]
["chr1",40072710,40097247,"PPT1",23.11,0.36,0.02,-6.01,0,"down","yes"]
["chr17",70169535,70180048,"KCNJ2",8.49,0.16,0.02,-5.72,0,"down","yes"]
["chr15",44711927,44717704,"B2M",179.05,3.81,0.02,-5.55,0,"down","yes"]
["chr19",48615393,48619127,"RPL18",87.67,2.04,0.02,-5.42,0,"down","yes"]
["chr6",31353817,31357196,"HLA-B",45.15,1.11,0.02,-5.35,0,"down","yes"]
["chrX",72255679,72277018,"RPS4X",45.19,1.2,0.03,-5.23,0,"down","yes"]
["chr14",73274834,73465941,"NUMB",12.14,0.32,0.03,-5.24,0,"down","yes"]
["chr19",48255675,48258199,"CARD8-AS1",15.57,0.41,0.03,-5.24,0,"down","yes"]
["chr2",218162845,218166995,"CXCR1",150.87,4.63,0.03,-5.02,0,"down","yes"]
["chr22",50523554,50530051,"TYMP",37.07,1.19,0.03,-4.96,0,"down","yes"]
["chr1",155689083,155738526,"DAP3",22.16,0.69,0.03,-5.01,0,"down","yes"]
["chr1",161541756,161550911,"FCGR3A",12.46,0.42,0.03,-4.91,0,"down","yes"]
["chr19",51745172,51751909,"FPR1",317.73,11.57,0.04,-4.78,0,"down","yes"]
["chr8",143579728,143597413,"EEF1D",35.58,1.22,0.03,-4.86,0,"down","yes"]
["chr16",18782968,18790362,"RPS15A",222.05,8.42,0.04,-4.72,0,"down","yes"]
["chr17",51166564,51171744,"NME2",37.49,1.35,0.04,-4.8,0,"down","yes"]
["chr9",129807881,129824134,"TOR1A",13.36,0.5,0.04,-4.74,0,"down","yes"]
["chr11",65120630,65122057,"FAU",65.35,2.49,0.04,-4.71,0,"down","yes"]
["chr15",44711959,44716559,"B2M",57.82,2.44,0.04,-4.57,0,"down","yes"]
["chr3",98515473,98523043,"CLDND1",19.76,0.85,0.04,-4.53,0,"down","yes"]
["chr19",1438419,1440494,"RPS15",166.63,7.38,0.04,-4.5,0,"down","yes"]
["chr1",111722064,111739424,"FAM212B",14.69,0.73,0.05,-4.34,0,"down","yes"]
["chr11",67438076,67443512,"CORO1B",10.16,0.47,0.05,-4.42,0,"down","yes"]
["chr15",88635627,88656415,"ISG20",19,0.95,0.05,-4.33,0,"down","yes"]
["chr1",39204246,39487177,"MACF1",1.46,0.07,0.05,-4.31,0,"down","yes"]
["chr5",171387829,171410884,"NPM1",18.51,0.92,0.05,-4.33,0,"down","yes"]
["chr17",4945667,4947469,"PFN1",189.07,10.1,0.05,-4.23,0,"down","yes"]
["chr19",54200874,54207647,"RPS9",61.1,3.16,0.05,-4.27,0,"down","yes"]
["chr8",23541470,23572203,"SLC25A37",4.56,0.25,0.05,-4.2,0,"down","yes"]
["chr17",64319415,64390878,"PECAM1",10.91,0.64,0.06,-4.09,0,"down","yes"]
["chr6",31268940,31354573,"USP8P1",44.3,2.42,0.05,-4.19,0,"down","yes"]
["chr15",42495614,42533054,"SNAP23",45.57,2.73,0.06,-4.06,0,"down","yes"]
["chr6",108212005,108261244,"SNX3",16.14,0.89,0.06,-4.18,0,"down","yes"]
["chr16",67192185,67198917,"E2F4",5.83,0.33,0.06,-4.13,0,"down","yes"]
["chr2",88846694,88947863,"IGKV1-5",34.43,2.12,0.06,-4.02,0,"down","yes"]
["chr14",55271303,55353609,"FBXO34",5.65,0.35,0.06,-4,0,"down","yes"]
["chr6",159679064,159693234,"SOD2",281.37,18.74,0.07,-3.91,0,"down","yes"]
["chr1",13749403,13788079,"PRDM2",3.24,0.21,0.06,-3.98,0,"down","yes"]
["chr1",161505430,161608794,"FCGR2A",4.2,0.28,0.07,-3.93,0,"down","yes"]
["chr14",22112342,22552137,"TRAC",9.66,0.6,0.06,-4.01,0,"down","yes"]
["chr19",23827162,23828049,"RPSAP58",52.24,3.48,0.07,-3.91,0,"down","yes"]
["chr5",177502088,177508877,"DOK3",7.05,0.45,0.06,-3.95,0,"down","yes"]
["chr11",95089810,95132645,"ENDOD1",5.95,0.4,0.07,-3.9,0,"down","yes"]
["chr19",54200871,54207522,"RPS9",29.91,1.99,0.07,-3.91,0,"down","yes"]
["chr8",30063126,30082948,"SARAF",6.51,0.43,0.07,-3.92,0,"down","yes"]
["chr10",43385617,43397346,"HNRNPF",5.86,0.4,0.07,-3.88,0,"down","yes"]
["chr12",56639880,56646060,"ATP5B",16.49,1.2,0.07,-3.78,0,"down","yes"]
["chr1",203799335,203854118,"ZBED6",3.65,0.27,0.07,-3.78,0,"down","yes"]
["chr13",21176645,21179084,"MRPL57",7.6,0.55,0.07,-3.78,0,"down","yes"]
["chr12",92140278,92145897,"BTG1",19.81,1.52,0.08,-3.71,0,"down","yes"]
["chr2",64631621,64653913,"SERTAD2",3.93,0.29,0.07,-3.75,0,"down","yes"]
["chr19",11597420,11619135,"ZNF627",3.74,0.27,0.07,-3.8,0,"down","yes"]
["chr20",3146519,3159897,"FASTKD5",7.16,0.54,0.08,-3.73,0,"down","yes"]
["chr2",88846694,89268506,"IGKV1-33",89.1,6.95,0.08,-3.68,0,"down","yes"]
["chr12",108645109,108731596,"CORO1C",18.9,1.59,0.08,-3.58,0,"down","yes"]
["chrX",65598663,65741931,"MSN",25.83,2.17,0.08,-3.57,0,"down","yes"]
["chr19",18173160,18178175,"AC007192.1",57.91,4.88,0.08,-3.57,0,"down","yes"]
["chr19",57769670,57780577,"ZNF586",6.37,0.51,0.08,-3.64,0,"down","yes"]
["chr14",92939862,93115279,"ITPK1",9.37,0.79,0.08,-3.57,0,"down","yes"]
["chr14",105851705,105865515,"IGHM",20.96,1.78,0.08,-3.56,0,"down","yes"]
["chr10",5765954,5813411,"GDI2",30.29,2.6,0.09,-3.54,0,"down","yes"]
["chr5",446149,467285,"EXOC3",11.94,1.02,0.09,-3.55,0,"down","yes"]
["chr19",1438401,1440494,"RPS15",67.86,5.96,0.09,-3.51,0,"down","yes"]
["chr12",108288044,108339317,"CMKLR1",1.71,0.14,0.08,-3.63,0,"down","yes"]
["chr12",8533305,8540963,"CLEC4E",6.23,0.53,0.09,-3.54,0,"down","yes"]
["chr10",124984317,125160513,"CTBP2",2.77,0.24,0.09,-3.5,0,"down","yes"]
["chr1",28329038,28335967,"MED18",6,0.52,0.09,-3.52,0,"down","yes"]
["chr20",31514428,31569567,"HM13",7.2,0.63,0.09,-3.52,0,"down","yes"]
["chr16",30064185,30070257,"ALDOA",14.3,1.29,0.09,-3.47,0,"down","yes"]
["chr12",106237877,106247988,"CKAP4",12.66,1.18,0.09,-3.43,0,"down","yes"]
["chr6",138404219,138422197,"HEBP2",3.59,0.33,0.09,-3.43,0,"down","yes"]
["chr18",3449704,3458411,"TGIF1",5.12,0.46,0.09,-3.49,0,"down","yes"]
["chr11",61964747,61967586,"FTH1",108.48,10.32,0.1,-3.39,0,"down","yes"]
["chr7",76326794,76359031,"YWHAG",11.06,1.05,0.1,-3.39,0,"down","yes"]
["chr1",155308794,155320609,"FDPS",6.68,0.6,0.09,-3.48,0,"down","yes"]
["chr13",27251583,27256568,"RPL21",124.2,12.01,0.1,-3.37,0,"down","yes"]
["chr14",73275107,73458617,"NUMB",10.44,1,0.1,-3.38,0,"down","yes"]
["chr7",135148072,135166215,"TMEM140",36.81,3.62,0.1,-3.35,0,"down","yes"]
["chr20",49245897,49278065,"ZNFX1",5.41,0.53,0.1,-3.36,0,"down","yes"]
["chr14",64209120,64226430,"SYNE2",2.31,0.21,0.09,-3.45,0,"down","yes"]
["chr9",133348252,133351431,"RPL7A",92.37,9.34,0.1,-3.31,0,"down","yes"]
["chr17",17136338,17185616,"MPRIP",3.05,0.29,0.09,-3.4,0,"down","yes"]
["chr5",151771910,151812785,"G3BP1",4.17,0.42,0.1,-3.32,0,"down","yes"]
["chr11",33858576,33891923,"LMO2",11.53,1.13,0.1,-3.35,0,"down","yes"]
["chr9",99105089,99154192,"TGFBR1",3.93,0.39,0.1,-3.33,0,"down","yes"]
["chr6",43511827,43516979,"YIPF3",9.33,0.92,0.1,-3.34,0,"down","yes"]
["chr16",18782968,18790334,"RPS15A",25.01,2.42,0.1,-3.37,0,"down","yes"]
["chr8",143577816,143597744,"NAPRT",4.15,0.41,0.1,-3.34,0,"down","yes"]
["chrX",66015461,66020422,"AL034397.3",16.55,1.7,0.1,-3.29,0,"down","yes"]
["chr8",26390362,26411048,"BNIP3L",40.82,4.24,0.1,-3.27,0,"down","yes"]
["chr12",53252096,53254404,"MFSD5",6.54,0.65,0.1,-3.33,0,"down","yes"]
["chr16",30065772,30070352,"ALDOA",30,3.17,0.11,-3.24,0,"down","yes"]
["chr16",18782969,18790260,"RPS15A",59.12,6.3,0.11,-3.23,0,"down","yes"]
["chr3",49357178,49358283,"GPX1",12.77,1.32,0.1,-3.28,0,"down","yes"]
["chrX",69160891,69165793,"PJA1",3.24,0.32,0.1,-3.33,0,"down","yes"]
["chrX",147911951,147951125,"FMR1",2.29,0.23,0.1,-3.29,0,"down","yes"]
["chr4",112274542,112285903,"TIFA",3.87,0.4,0.1,-3.26,0,"down","yes"]
["chr22",21549447,21624034,"UBE2L3",4.79,0.5,0.1,-3.26,0,"down","yes"]
["chr2",218273735,218292579,"TMBIM1",33.77,3.71,0.11,-3.19,0,"down","yes"]
["chr10",74838700,75032622,"KAT6B",1.29,0.13,0.1,-3.27,0,"down","yes"]
["chr4",52712781,52714137,"DANCR",11.99,1.24,0.1,-3.28,0,"down","yes"]
["chr17",31317560,31321884,"EVI2A",93.09,10.31,0.11,-3.17,0,"down","yes"]
["chr2",70295975,70302090,"FAM136A",7.08,0.75,0.11,-3.25,0,"down","yes"]
["chr1",39678648,39691689,"HPCAL4",1.51,0.15,0.1,-3.29,0,"down","yes"]
["chr13",45337198,45341122,"TPT1",54.54,6.02,0.11,-3.18,0,"down","yes"]
["chr8",66628487,66667217,"VCPIP1",3.69,0.41,0.11,-3.18,0,"down","yes"]
["chr19",2101350,2137093,"AP3D1",2.31,0.24,0.11,-3.25,0,"down","yes"]
["chr5",140631728,140633701,"CD14",27.29,3.03,0.11,-3.17,0,"down","yes"]
["chr13",27251597,27256568,"RPL21",157.74,17.75,0.11,-3.15,0,"down","yes"]
["chr8",130052104,130180862,"ASAP1",3.3,0.36,0.11,-3.19,0,"down","yes"]
["chr7",55470613,55572525,"VOPP1",27.99,3.17,0.11,-3.14,0,"down","yes"]
["chr16",18781295,18790334,"RPS15A",119.78,13.75,0.11,-3.12,0,"down","yes"]
["chr10",130136399,130179664,"GLRX3",9.49,1.04,0.11,-3.2,0,"down","yes"]
["chr6",24797373,24950536,"RIPOR2",2.53,0.28,0.11,-3.17,0,"down","yes"]
["chr19",49555711,49580572,"NOSIP",29.27,3.35,0.11,-3.13,0,"down","yes"]
["chr11",75399531,75422280,"RPS3",30.18,3.53,0.12,-3.1,0,"down","yes"]
["chr1",155659446,155688774,"YY1AP1",3.41,0.38,0.11,-3.17,0,"down","yes"]
["chr14",23559612,23567324,"AP1G2",3.13,0.34,0.11,-3.19,0,"down","yes"]
["chr11",60378485,60395951,"MS4A7",3.53,0.4,0.11,-3.14,0,"down","yes"]
["chr11",61964566,61967631,"FTH1",242.44,29.47,0.12,-3.04,0,"down","yes"]
["chr8",30063098,30083124,"SARAF",20.82,2.5,0.12,-3.06,0,"down","yes"]
["chr19",48615328,48619536,"RPL18",269.87,33,0.12,-3.03,0,"down","yes"]
["chr12",56116632,56117710,"RPL41",24.19,2.74,0.11,-3.14,0,"down","yes"]
["chr11",64230278,64234281,"DNAJC4",8.74,1.02,0.12,-3.1,0,"down","yes"]
["chr6",30727866,30742706,"FLOT1",30.62,3.73,0.12,-3.04,0,"down","yes"]
["chr8",73991352,74029087,"LY96",35.11,4.25,0.12,-3.05,0,"down","yes"]
["chr20",49278642,49289260,"ZFAS1",22.26,2.69,0.12,-3.05,0,"down","yes"]
["chr19",52612378,52618040,"ZNF83",2.03,0.24,0.12,-3.1,0,"down","yes"]
["chr17",76734293,76737367,"SRSF2",10.39,1.29,0.12,-3.01,0,"down","yes"]
["chr2",234493041,234497053,"ARL4C",17.19,2.17,0.13,-2.98,0,"down","yes"]
["chr19",12163064,12189881,"ZNF136",2.14,0.25,0.12,-3.08,0,"down","yes"]
["chr16",11549,14089,"DDX11L10",12.25,1.52,0.12,-3.01,0,"down","yes"]
["chr7",100572256,100586154,"LRCH4",17.15,2.17,0.13,-2.98,0,"down","yes"]
["chr17",42998436,43002959,"RPL27",31.92,3.88,0.12,-3.04,0,"down","yes"]
["chr19",16197934,16235345,"AP1M1",4.27,0.52,0.12,-3.04,0,"down","yes"]
["chr19",5690306,5691653,"RPL36",39.1,4.88,0.12,-3,0,"down","yes"]
["chr4",39454126,39458931,"RPL9",43.07,5.45,0.13,-2.98,0,"down","yes"]
["chrX",110003095,110177788,"TMEM164",1.26,0.15,0.12,-3.06,0,"down","yes"]
["chr16",18782968,18790334,"RPS15A",26.26,3.23,0.12,-3.02,0,"down","yes"]
["chr19",34677689,34686391,"ZNF302",3.09,0.38,0.12,-3.04,0,"down","yes"]
["chr1",40072729,40097252,"PPT1",16.41,2.1,0.13,-2.97,0,"down","yes"]
["chr8",143612618,143617482,"TSTA3",5.21,0.62,0.12,-3.07,0,"down","yes"]
["chr8",9136255,9150696,"PPP1R3B",10.06,1.3,0.13,-2.96,0,"down","yes"]
["chr17",75979231,76005998,"TEN1-CDK3",2.53,0.32,0.12,-3,0,"down","yes"]
["chr8",38105793,38139703,"ASH2L",6.1,0.78,0.13,-2.97,0,"down","yes"]
["chr3",47802928,47850193,"DHX30",1.49,0.18,0.12,-3.03,0,"down","yes"]
["chr11",65653601,65662895,"RELA",3.11,0.4,0.13,-2.97,0,"down","yes"]
["chr16",89286663,89317075,"ANKRD11",2.88,0.37,0.13,-2.98,0,"down","yes"]
["chr18",49488561,49492432,"RPL17",56.97,7.63,0.13,-2.9,0,"down","yes"]
["chr5",40825262,40835335,"RPL37",36.2,4.98,0.14,-2.86,0,"down","yes"]
["chr17",17246837,17281191,"COPS3",8.29,1.11,0.13,-2.9,0,"down","yes"]
["chrX",153794639,153798505,"SSR4",35.39,4.79,0.14,-2.89,0,"down","yes"]
["chr11",60455847,60470058,"MS4A1",3.66,0.48,0.13,-2.93,0,"down","yes"]
["chr22",50525755,50529996,"TYMP",3.8,0.49,0.13,-2.96,0,"down","yes"]
["chr12",67648721,67665406,"DYRK2",3,0.41,0.14,-2.86,0,"down","yes"]
["chr11",612583,615650,"IRF7",4.39,0.57,0.13,-2.93,0,"down","yes"]
["chr7",100088981,100091905,"COPS6",9.5,1.27,0.13,-2.9,0,"down","yes"]
["chrX",48893447,48897762,"TIMM17B",13.35,1.8,0.13,-2.89,0,"down","yes"]
["chr2",46901874,46915868,"MCFD2",4.81,0.66,0.14,-2.86,0,"down","yes"]
["chr15",88635621,88656483,"ISG20",3.83,0.5,0.13,-2.95,0,"down","yes"]
["chr4",108620656,108630412,"RPL34",198.73,28.06,0.14,-2.82,0,"down","yes"]
["chr11",14504913,14520363,"PSMA1",21.57,3.01,0.14,-2.84,0,"down","yes"]
["chr19",51745172,51751893,"FPR1",76.98,10.89,0.14,-2.82,0,"down","yes"]
["chr14",69767124,69771991,"SRSF5",19.38,2.72,0.14,-2.83,0,"down","yes"]
["chr17",82458712,82488259,"NARF",11.78,1.66,0.14,-2.82,0,"down","yes"]
["chrX",153802168,153830548,"PDZD4",2.8,0.38,0.14,-2.87,0,"down","yes"]
["chr11",18396278,18407847,"LDHA",3.58,0.48,0.13,-2.9,0,"down","yes"]
["chr7",36855551,37449223,"ELMO1",3.39,0.46,0.14,-2.88,0,"down","yes"]
["chr19",54200879,54207644,"RPS9",14.25,1.99,0.14,-2.84,0,"down","yes"]
["chr1",153543613,153545063,"S100A4",12.46,1.69,0.14,-2.88,0,"down","yes"]
["chr5",90515611,90529561,"LYSMD3",1.84,0.25,0.14,-2.87,0,"down","yes"]
["chr12",54301164,54351820,"COPZ1",8.78,1.25,0.14,-2.81,0,"down","yes"]
["chr10",121740424,121928036,"ATE1",1.11,0.15,0.13,-2.9,0,"down","yes"]
["chr5",74640023,74721288,"HEXB",4.28,0.59,0.14,-2.86,0,"down","yes"]
["chr11",6733731,6746470,"GVINP1",11.58,1.58,0.14,-2.87,0,"down","yes"]
["chr16",51645756,51647132,"HNRNPA1P48",23.12,3.38,0.15,-2.77,0,"down","yes"]
["chr11",126355660,126414604,"ST3GAL4",4.62,0.65,0.14,-2.84,0,"down","yes"]
["chr15",75206049,75212169,"C15orf39",3.29,0.48,0.14,-2.79,0,"down","yes"]
["chr1",161505430,161526907,"FCGR2A",19.08,2.86,0.15,-2.74,0,"down","yes"]
["chr10",78033863,78037602,"RPS24",76.52,11.48,0.15,-2.74,0,"down","yes"]
["chr13",49451552,49495002,"SETDB2",2.21,0.32,0.15,-2.77,0,"down","yes"]
["chr2",171687409,171748411,"DYNC1I2",7.01,1.05,0.15,-2.74,0,"down","yes"]
["chrX",110002635,110177784,"TMEM164",5.37,0.81,0.15,-2.73,0,"down","yes"]
["chr19",17305668,17306843,"MRPL34",15.12,2.25,0.15,-2.75,0,"down","yes"]
["chr1",154328831,154349459,"ATP8B2",6.47,0.99,0.15,-2.71,0,"down","yes"]
["chr16",46407,53628,"POLR3K",5.11,0.76,0.15,-2.75,0,"down","yes"]
["chr10",97356701,97373593,"RRP12",2.55,0.39,0.15,-2.72,0,"down","yes"]
["chr11",61964566,61967633,"FTH1",137.25,21.78,0.16,-2.66,0,"down","yes"]
["chr19",11435745,11450867,"PRKCSH",2.78,0.4,0.15,-2.78,0,"down","yes"]
["chr11",67288547,67302481,"ANKRD13D",7.86,1.23,0.16,-2.68,0,"down","yes"]
["chr2",99400475,99489973,"REV1",1.41,0.21,0.15,-2.75,0,"down","yes"]
["chr2",101001715,101007267,"RPL31",5.14,0.78,0.15,-2.72,0,"down","yes"]
["chr11",202926,207428,"BET1L",8.64,1.36,0.16,-2.67,0,"down","yes"]
["chr7",124822386,124929981,"POT1",4.44,0.69,0.16,-2.68,0,"down","yes"]
["chr1",16440736,16460077,"NECAP2",7.6,1.18,0.15,-2.69,0,"down","yes"]
["chr19",35904403,35908275,"TYROBP",27.84,4.33,0.16,-2.68,0,"down","yes"]
["chr20",25674215,25696841,"ZNF337",2.84,0.43,0.15,-2.71,0,"down","yes"]
["chrX",49074433,49080097,"WDR45",2.23,0.33,0.15,-2.75,0,"down","yes"]
["chr11",76349956,76380942,"THAP12",14.31,2.31,0.16,-2.63,0,"down","yes"]
["chr7",150625378,150632648,"GIMAP6",1.75,0.27,0.15,-2.7,0,"down","yes"]
["chr15",50277263,50355153,"GABPB1",2.1,0.32,0.15,-2.73,0,"down","yes"]
["chr2",3575205,3580919,"RPS7",397.1,64.95,0.16,-2.61,0,"down","yes"]
["chr1",161541765,161550623,"FCGR3A",61.12,9.99,0.16,-2.61,0,"down","yes"]
["chr11",35662805,35818007,"TRIM44",3.07,0.5,0.16,-2.62,0,"down","yes"]
["chr6",31580555,31582427,"LTB",43.73,7.11,0.16,-2.62,0,"down","yes"]
["chr1",209756032,209779655,"TRAF3IP3",2.97,0.46,0.15,-2.71,0,"down","yes"]
["chr16",172894,173675,"HBA2",2266.39,374.14,0.17,-2.6,0,"down","yes"]
["chr4",6687448,6690519,"LINC002481",3.46,0.54,0.16,-2.67,0,"down","yes"]
["chr1",20499448,20508161,"MUL1",6.69,1.09,0.16,-2.62,0,"down","yes"]
["chr11",65572462,65574190,"FAM89B",6.61,1.05,0.16,-2.66,0,"down","yes"]
["chr14",63852983,64226432,"SYNE2",1.52,0.25,0.17,-2.58,0,"down","yes"]
["chr8",76980258,77000226,"PEX2",5.48,0.92,0.17,-2.58,0,"down","yes"]
["chr19",8580242,8608265,"ADAMTS10",1.27,0.2,0.16,-2.66,0,"down","yes"]
["chr20",23079349,23086340,"CD93",13.39,2.28,0.17,-2.55,0,"down","yes"]
["chr16",30064274,30070414,"ALDOA",18.16,3.08,0.17,-2.56,0,"down","yes"]
["chr2",85577491,85582031,"VAMP8",79.07,13.52,0.17,-2.55,0,"down","yes"]
["chr2",27435582,27442255,"NRBP1",2.54,0.41,0.16,-2.62,0,"down","yes"]
["chr1",228393673,228405904,"TRIM11",1.34,0.22,0.16,-2.6,0,"down","yes"]
["chr7",143811968,143836933,"AC099548.2",2.57,0.41,0.16,-2.66,0,"down","yes"]
["chr11",65572528,65574192,"FAM89B",13.76,2.34,0.17,-2.56,0,"down","yes"]
["chr20",59019254,59026654,"TUBB1",88.92,15.55,0.17,-2.52,0,"down","yes"]
["chr3",39406735,39412434,"RPSA",236.9,41.46,0.18,-2.51,0,"down","yes"]
["chr19",14736079,14776756,"ADGRE2",5.52,0.94,0.17,-2.55,0,"down","yes"]
["chr17",82458185,82488255,"NARF",3.31,0.55,0.17,-2.59,0,"down","yes"]
["chr10",103088060,103181329,"NT5C2",5.5,0.95,0.17,-2.53,0,"down","yes"]
["chrX",119786506,119791595,"RPL39",3.33,0.56,0.17,-2.58,0,"down","yes"]
["chr20",50934945,50958521,"DPM1",4.68,0.77,0.16,-2.61,0,"down","yes"]
["chr8",127736084,127741434,"MYC",2.96,0.5,0.17,-2.57,0,"down","yes"]
["chr3",39263495,39281735,"CX3CR1",5.28,0.92,0.17,-2.52,0,"down","yes"]
["chr8",127736069,127741434,"MYC",2.94,0.5,0.17,-2.57,0,"down","yes"]
["chr19",54449224,54461400,"LENG8",1.08,0.18,0.17,-2.59,0,"down","yes"]
["chr15",49858239,50113316,"ATP8B4",1.14,0.19,0.17,-2.56,0,"down","yes"]
["chr5",171387851,171407125,"NPM1",101.92,18.31,0.18,-2.48,0,"down","yes"]
["chr3",121769994,121835034,"IQCB1",2.3,0.38,0.16,-2.6,0,"down","yes"]
["chr8",38787263,38853028,"TACC1",1.26,0.22,0.17,-2.54,0,"down","yes"]
["chr3",171063881,171460063,"TNIK",1.31,0.22,0.17,-2.59,0,"down","yes"]
["chr19",54200858,54206565,"RPS9",34.37,6.08,0.18,-2.5,0,"down","yes"]
["chr8",30063130,30083153,"SARAF",79.29,14.38,0.18,-2.46,0,"down","yes"]
["chr15",43185257,43197176,"CCNDBP1",27.68,5.03,0.18,-2.46,0,"down","yes"]
["chr13",77044902,77087514,"MYCBP2",4.56,0.81,0.18,-2.49,0,"down","yes"]
["chr2",27428640,27442255,"NRBP1",17.7,3.2,0.18,-2.47,0.01,"down","yes"]
["chrX",48898041,48903143,"PQBP1",13.24,2.36,0.18,-2.49,0.01,"down","yes"]
["chr1",65420587,65436007,"LEPROT",9.89,1.81,0.18,-2.45,0.01,"down","yes"]
["chr11",5253389,5254741,"HBG2",21.56,3.75,0.17,-2.52,0.01,"down","yes"]
["chr1",44214833,44220681,"DMAP1",1.53,0.27,0.18,-2.5,0.01,"down","yes"]
["chr7",2728112,2844324,"GNA12",6.36,1.17,0.18,-2.44,0.01,"down","yes"]
["chr1",174799773,174958462,"RABGAP1L",7.88,1.42,0.18,-2.47,0.01,"down","yes"]
["chr16",30075990,30085377,"PPP4C",36.32,6.73,0.19,-2.43,0.01,"down","yes"]
["chr3",23916545,23920977,"RPL15",245.79,45.95,0.19,-2.42,0.01,"down","yes"]
["chr17",63698478,63699162,"LIMD2",12.3,2.18,0.18,-2.5,0.01,"down","yes"]
["chr1",173864034,173867729,"GAS5",11.18,2.02,0.18,-2.47,0.01,"down","yes"]
["chr11",65096227,65108399,"VPS51",6.37,1.12,0.18,-2.51,0.01,"down","yes"]
["chr3",49724295,49786540,"IP6K1",1.59,0.28,0.18,-2.5,0.01,"down","yes"]
["chr8",108233394,108248698,"EIF3E",20.4,3.74,0.18,-2.45,0.01,"down","yes"]
["chr6",32948613,32953108,"HLA-DMA",9.34,1.68,0.18,-2.47,0.01,"down","yes"]
["chr1",109621101,109632055,"AMPD2",9.67,1.81,0.19,-2.42,0.01,"down","yes"]
["chr16",172890,173710,"HBA2",3417.82,645.48,0.19,-2.4,0.01,"down","yes"]
["chr5",181236937,181243902,"RACK1",10.47,1.91,0.18,-2.45,0.01,"down","yes"]
["chr18",49488481,49492547,"RPL17-C18orf32",264.44,49.95,0.19,-2.4,0.01,"down","yes"]
["chr22",31496538,31618548,"SFI1",1.13,0.2,0.17,-2.53,0.01,"down","yes"]
["chr6",292097,351355,"DUSP22",4.45,0.79,0.18,-2.49,0.01,"down","yes"]
["chr5",163505626,163519149,"MAT2B",2.4,0.43,0.18,-2.46,0.01,"down","yes"]
["chr21",37085790,37203112,"TTC3",1.91,0.36,0.19,-2.42,0.01,"down","yes"]
["chr19",49555718,49580579,"NOSIP",5.96,1.08,0.18,-2.47,0.01,"down","yes"]
["chrX",47651796,47659169,"UXT",8.83,1.55,0.18,-2.51,0.01,"down","yes"]
["chr8",143579722,143597396,"EEF1D",10.92,1.94,0.18,-2.49,0.01,"down","yes"]
["chr6",157289386,157323601,"TMEM242",1.38,0.25,0.18,-2.46,0.01,"down","yes"]
["chr7",140696672,140706646,"NDUFB2",35.69,6.73,0.19,-2.41,0.01,"down","yes"]
["chrX",124346344,124373155,"SH2D1A",15.25,2.92,0.19,-2.39,0.01,"down","yes"]
["chr3",150603291,150627693,"SELENOT",4.83,0.86,0.18,-2.49,0.01,"down","yes"]
["chr5",80626228,80654983,"DHFR",1.73,0.32,0.18,-2.44,0.01,"down","yes"]
["chr12",6534534,6538359,"GAPDH",84.65,16.38,0.19,-2.37,0.01,"down","yes"]
["chr12",49989164,50025400,"RACGAP1",1.5,0.27,0.18,-2.48,0.01,"down","yes"]
["chr1",112701131,112707434,"RHOC",5.34,0.99,0.19,-2.43,0.01,"down","yes"]
["chr6",30727709,30740853,"FLOT1",4.63,0.87,0.19,-2.42,0.01,"down","yes"]
["chr10",89301955,89309276,"IFIT2",15.18,2.96,0.2,-2.36,0.01,"down","yes"]
["chr11",60172014,60183104,"MS4A6A",28.49,5.56,0.2,-2.36,0.01,"down","yes"]
["chr10",16590620,16817454,"RSU1",4.25,0.82,0.19,-2.38,0.01,"down","yes"]
["chr11",117986348,118001479,"IL10RA",10.14,1.98,0.19,-2.36,0.01,"down","yes"]
["chrX",96685017,97469765,"DIAPH2",1.67,0.31,0.19,-2.42,0.01,"down","yes"]
["chr5",163503114,163519336,"MAT2B",14.54,2.85,0.2,-2.35,0.01,"down","yes"]
["chr1",93151858,93180516,"TMED5",1.08,0.2,0.18,-2.45,0.01,"down","yes"]
["chrX",155258241,155264589,"RAB39B",1.78,0.33,0.19,-2.42,0.01,"down","yes"]
["chr4",38772239,38782958,"TLR10",1.67,0.32,0.19,-2.39,0.01,"down","yes"]
["chr14",34432789,34462356,"SPTSSA",4.07,0.79,0.19,-2.37,0.01,"down","yes"]
["chr5",151029947,151081084,"TNIP1",4.34,0.84,0.19,-2.37,0.01,"down","yes"]
["chr16",87391800,87404779,"MAP1LC3B",29.14,5.82,0.2,-2.32,0.01,"down","yes"]
["chr17",1344272,1400378,"YWHAE",33.98,6.79,0.2,-2.32,0.01,"down","yes"]
["chr8",143579728,143597428,"EEF1D",6.75,1.27,0.19,-2.41,0.01,"down","yes"]
["chr2",102418601,102452568,"IL18RAP",8.48,1.68,0.2,-2.33,0.01,"down","yes"]
["chr20",49278178,49289260,"ZFAS1",5.08,0.97,0.19,-2.39,0.01,"down","yes"]
["chr3",186783577,186789897,"EIF4A2",26.14,5.25,0.2,-2.31,0.01,"down","yes"]
["chr1",150574551,150579738,"MCL1",1.96,0.38,0.19,-2.37,0.01,"down","yes"]
["chr16",30114105,30123294,"MAPK3",19.73,3.97,0.2,-2.31,0.01,"down","yes"]
["chr12",120196699,120201099,"RPLP0",162.32,32.99,0.2,-2.3,0.01,"down","yes"]
["chr17",81868870,81871337,"ARHGDIA",7.22,1.39,0.19,-2.38,0.01,"down","yes"]
["chr1",44850778,44986610,"EIF2B3",3.41,0.66,0.19,-2.38,0.01,"down","yes"]
["chr19",34956354,34964049,"ZNF792",1.57,0.3,0.19,-2.38,0.01,"down","yes"]
["chr14",22456013,22466583,"TRDC",4.74,0.95,0.2,-2.32,0.01,"down","yes"]
["chr19",54200809,54206847,"RPS9",30.6,6.25,0.2,-2.29,0.01,"down","yes"]
["chr1",150646225,150697024,"GOLPH3L",3.56,0.71,0.2,-2.32,0.01,"down","yes"]
["chr19",18571858,18573790,"UBA52",8.34,1.6,0.19,-2.39,0.01,"down","yes"]
["chr4",15605006,15655341,"FBXL5",10,2.05,0.21,-2.29,0.01,"down","yes"]
["chr6",63646526,63714509,"PHF3",1.72,0.35,0.2,-2.31,0.01,"down","yes"]
["chr11",125592867,125620888,"STT3A",2.82,0.55,0.19,-2.36,0.01,"down","yes"]
["chr7",142855124,142871094,"EPHB6",2.18,0.44,0.2,-2.32,0.01,"down","yes"]
["chr6",42928680,42941142,"CNPY3",26.77,5.57,0.21,-2.27,0.01,"down","yes"]
["chr13",45338185,45341086,"TPT1",6.29,1.24,0.2,-2.34,0.01,"down","yes"]
["chr17",75633434,75641404,"SMIM5",8.54,1.75,0.2,-2.29,0.01,"down","yes"]
["chr19",1269266,1273172,"CIRBP",2.46,0.48,0.19,-2.37,0.01,"down","yes"]
["chr12",48688464,48716898,"CCNT1",3.01,0.62,0.21,-2.27,0.01,"down","yes"]
["chr8",143579728,143597415,"EEF1D",5.81,1.2,0.21,-2.28,0.01,"down","yes"]
["chr12",44508282,44876355,"NELL2",1.8,0.36,0.2,-2.32,0.01,"down","yes"]
["chr2",219249711,219254032,"TUBA4A",45.44,9.57,0.21,-2.25,0.01,"down","yes"]
["chr17",8435908,8467658,"NDEL1",4.74,0.97,0.2,-2.29,0.01,"down","yes"]
["chr22",50527792,50530012,"TYMP",5.04,1.03,0.2,-2.29,0.01,"down","yes"]
["chr7",44039523,44042306,"LINC00957",1.86,0.37,0.2,-2.33,0.01,"down","yes"]
["chr17",76736311,76778572,"MFSD11",2.05,0.41,0.2,-2.31,0.01,"down","yes"]
["chr8",143580620,143587564,"EEF1D",5.35,1.08,0.2,-2.3,0.01,"down","yes"]
["chr14",50905218,50944483,"PYGL",5.52,1.15,0.21,-2.27,0.01,"down","yes"]
["chr17",18184239,18209954,"ALKBH5",10.39,2.19,0.21,-2.25,0.01,"down","yes"]
["chr7",108470422,108526071,"PNPLA8",1.13,0.23,0.2,-2.31,0.01,"down","yes"]
["chr4",17577304,17607967,"LAP3",3.94,0.81,0.2,-2.29,0.01,"down","yes"]
["chr11",124115404,124124841,"VWA5A",2.59,0.52,0.2,-2.32,0.01,"down","yes"]
["chr1",155689091,155738526,"DAP3",3.53,0.71,0.2,-2.31,0.01,"down","yes"]
["chr16",3065663,3069440,"IL32",5.77,1.14,0.2,-2.33,0.01,"down","yes"]
["chr17",74203704,74209896,"RPL38",209.9,45.11,0.21,-2.22,0.01,"down","yes"]
["chr19",17860763,17863304,"RPL18A",97.04,21.02,0.22,-2.21,0.01,"down","yes"]
["chr17",16381013,16382745,"UBB",31.73,6.79,0.21,-2.22,0.01,"down","yes"]
["chr17",74203694,74209461,"RPL38",12.06,2.47,0.2,-2.29,0.01,"down","yes"]
["chr4",17577192,17607968,"LAP3",3.74,0.78,0.21,-2.26,0.01,"down","yes"]
["chr3",49674489,49683511,"APEH",9.08,1.96,0.22,-2.21,0.01,"down","yes"]
["chr3",157149287,157160178,"CCNL1",7.26,1.54,0.21,-2.23,0.01,"down","yes"]
["chr10",16593313,16817463,"RSU1",14.45,3.11,0.22,-2.22,0.01,"down","yes"]
["chr15",59662865,59689443,"BNIP2",2.13,0.45,0.21,-2.26,0.01,"down","yes"]
["chr11",64764606,64778747,"SF1",6.35,1.38,0.22,-2.2,0.01,"down","yes"]
["chr17",16438993,16441570,"LRRC75A-AS1",39.81,8.74,0.22,-2.19,0.01,"down","yes"]
["chr5",163505587,163519309,"MAT2B",10.99,2.41,0.22,-2.19,0.01,"down","yes"]
["chr13",45333471,45341284,"TPT1",29.25,6.49,0.22,-2.17,0.01,"down","yes"]
["chr1",101236888,101241518,"S1PR1",2.04,0.43,0.21,-2.23,0.01,"down","yes"]
["chr12",95217746,95302790,"VEZT",1.44,0.31,0.21,-2.23,0.01,"down","yes"]
["chr7",116862600,116918188,"CAPZA2",26.98,5.97,0.22,-2.18,0.01,"down","yes"]
["chr7",87345695,87399795,"CROT",1.96,0.42,0.21,-2.23,0.01,"down","yes"]
["chr13",113177611,113208666,"PCID2",3.05,0.64,0.21,-2.25,0.01,"down","yes"]
["chr13",99254714,99258428,"GPR18",9.55,2.09,0.22,-2.19,0.01,"down","yes"]
["chr10",100150094,100188334,"ERLIN1",1.18,0.25,0.21,-2.23,0.01,"down","yes"]
["chr4",39455811,39458931,"RPL9",28.85,6.4,0.22,-2.17,0.01,"down","yes"]
["chr14",64703935,64750602,"PLEKHG3",6.19,1.38,0.22,-2.16,0.01,"down","yes"]
["chr2",219374196,219387932,"DNPEP",6.47,1.42,0.22,-2.19,0.01,"down","yes"]
["chr8",94925972,94949411,"TP53INP1",3,0.66,0.22,-2.19,0.01,"down","yes"]
["chr1",32651142,32680053,"RBBP4",7.43,1.63,0.22,-2.19,0.01,"down","yes"]
["chr16",30065777,30070380,"ALDOA",32.57,7.31,0.22,-2.16,0.01,"down","yes"]
["chr3",12839051,12841543,"RPL32",10.05,2.15,0.21,-2.22,0.01,"down","yes"]
["chr19",18557888,18569297,"KXD1",5.45,1.18,0.22,-2.21,0.02,"down","yes"]
["chr19",1249888,1258699,"MIDN",1.25,0.26,0.21,-2.26,0.02,"down","yes"]
["chr16",30350766,30355361,"CD2BP2",16.82,3.8,0.23,-2.15,0.02,"down","yes"]
["chr6",37482920,37499922,"CCDC167",8.41,1.8,0.21,-2.22,0.02,"down","yes"]
["chr1",86348738,86396340,"ODF2L",2.16,0.46,0.21,-2.23,0.02,"down","yes"]
["chr4",122324464,122362752,"KIAA1109",2.85,0.63,0.22,-2.17,0.02,"down","yes"]
["chr11",18396266,18408218,"LDHA",3.02,0.66,0.22,-2.2,0.02,"down","yes"]
["chr17",82018703,82022918,"CENPX",5.4,1.13,0.21,-2.25,0.02,"down","yes"]
["chr12",49184796,49189324,"TUBA1A",216.81,49.39,0.23,-2.13,0.02,"down","yes"]
["chr4",48497541,48557703,"FRYL",1.38,0.31,0.22,-2.17,0.02,"down","yes"]
["chr5",139274104,139329757,"MATR3",6.77,1.52,0.22,-2.16,0.02,"down","yes"]
["chr2",241106295,241109780,"PASK",2.64,0.57,0.22,-2.21,0.02,"down","yes"]
["chr7",22510616,22511999,"EEF1A1P6",12.69,2.85,0.22,-2.15,0.02,"down","yes"]
["chr9",124353466,124415439,"PSMB7",19.33,4.36,0.23,-2.15,0.02,"down","yes"]
["chr19",35904461,35908223,"TYROBP",22.62,5.09,0.22,-2.15,0.02,"down","yes"]
["chr6",70566917,70589569,"SDHAF4",3.04,0.65,0.21,-2.23,0.02,"down","yes"]
["chr15",59639109,59657479,"GTF2A2",4.62,0.98,0.21,-2.24,0.02,"down","yes"]
["chr7",102363897,102426676,"PRKRIP1",1.95,0.43,0.22,-2.18,0.02,"down","yes"]
["chr19",53066614,53103434,"ZNF160",1.3,0.28,0.22,-2.2,0.02,"down","yes"]
["chr3",186783577,186789881,"EIF4A2",4.59,1.02,0.22,-2.17,0.02,"down","yes"]
["chr9",36136742,36162910,"GLIPR2",4.45,0.96,0.21,-2.22,0.02,"down","yes"]
["chr17",42313324,42388568,"STAT3",7.91,1.82,0.23,-2.12,0.02,"down","yes"]
["chr15",59659146,59689534,"BNIP2",1.93,0.43,0.23,-2.15,0.02,"down","yes"]
["chr13",39009866,39038076,"PROSER1",1.87,0.42,0.22,-2.15,0.02,"down","yes"]
["chrX",48897931,48903136,"PQBP1",11.91,2.69,0.23,-2.14,0.02,"down","yes"]
["chr17",7307974,7312455,"EIF5A",6.55,1.47,0.22,-2.16,0.02,"down","yes"]
["chr16",71895543,71929010,"IST1",5.45,1.24,0.23,-2.14,0.02,"down","yes"]
["chr1",206913632,206921941,"FCMR",7.05,1.52,0.22,-2.21,0.02,"down","yes"]
["chr14",94376977,94390665,"SERPINA1",22.44,5.2,0.23,-2.11,0.02,"down","yes"]
["chr1",116514535,116571039,"CD58",13.47,3.07,0.23,-2.13,0.02,"down","yes"]
["chr6",32190766,32192906,"GPSM3",74.89,17.42,0.23,-2.1,0.02,"down","yes"]
["chr19",1438386,1440494,"RPS15",130.3,30.34,0.23,-2.1,0.02,"down","yes"]
["chr4",182890255,182917594,"DCTD",2.23,0.49,0.22,-2.19,0.02,"down","yes"]
["chr1",244051283,244057476,"ZBTB18",3.78,0.87,0.23,-2.12,0.02,"down","yes"]
["chr19",45818913,45863130,"SYMPK",1.14,0.26,0.22,-2.16,0.02,"down","yes"]
["chr14",71932439,72562476,"RGS6",1.69,0.37,0.22,-2.21,0.02,"down","yes"]
["chr3",149738470,149752499,"COMMD2",4.55,1.05,0.23,-2.11,0.02,"down","yes"]
["chrX",154398372,154402339,"RPL10",324.4,76.55,0.24,-2.08,0.02,"down","yes"]
["chr12",49127782,49186065,"AC011603.2",4.67,1.06,0.23,-2.14,0.02,"down","yes"]
["chr6",30720201,30725426,"TUBB",46.27,10.96,0.24,-2.08,0.02,"down","yes"]
["chr1",234604269,234609525,"IRF2BP2",2.64,0.61,0.23,-2.11,0.02,"down","yes"]
["chr9",137077501,137084538,"UAP1L1",1.72,0.39,0.23,-2.14,0.02,"down","yes"]
["chr7",142786321,142793369,"AC245427.1",7.57,1.77,0.23,-2.09,0.02,"down","yes"]
["chr4",112297343,112442606,"ALPK1",1.61,0.37,0.23,-2.11,0.02,"down","yes"]
["chr7",149872968,149880698,"ATP6V0E2",1.39,0.31,0.22,-2.19,0.02,"down","yes"]
["chr7",149872968,149880693,"ATP6V0E2",1.39,0.31,0.22,-2.19,0.02,"down","yes"]
["chr10",22316386,22320306,"COMMD3",1.57,0.35,0.22,-2.17,0.02,"down","yes"]
["chr15",78923059,78937233,"CTSH",4.37,0.97,0.22,-2.17,0.02,"down","yes"]
["chr6",31580555,31582425,"LTB",81.12,19.4,0.24,-2.06,0.02,"down","yes"]
["chr3",50350695,50354079,"CYB561D2",5.04,1.16,0.23,-2.12,0.02,"down","yes"]
["chr6",31797396,31806984,"LSM2",13.76,3.23,0.23,-2.09,0.02,"down","yes"]
["chr7",142618849,142619532,"TRBV19",9.43,2.13,0.23,-2.15,0.02,"down","yes"]
["chr16",87959871,88077315,"BANP",1.85,0.42,0.23,-2.14,0.02,"down","yes"]
["chr8",143574785,143597679,"NAPRT",4.31,1.02,0.24,-2.07,0.02,"down","yes"]
["chr3",27376606,27484347,"SLC4A7",1.95,0.45,0.23,-2.1,0.02,"down","yes"]
["chr12",122207662,122226052,"DIABLO",3.6,0.82,0.23,-2.14,0.02,"down","yes"]
["chr19",45507486,45527019,"VASP",36.93,8.9,0.24,-2.05,0.02,"down","yes"]
["chr4",108620566,108630479,"RPL34",196.56,47.44,0.24,-2.05,0.02,"down","yes"]
["chr3",111979035,111993363,"ABHD10",4.31,1.02,0.24,-2.08,0.02,"down","yes"]
["chr14",95709967,95714196,"TCL1A",7.54,1.78,0.24,-2.08,0.02,"down","yes"]
["chr19",49555711,49580558,"NOSIP",16.91,4.04,0.24,-2.07,0.02,"down","yes"]
["chr22",42618853,42646979,"CYB5R3",4.3,1.01,0.23,-2.09,0.02,"down","yes"]
["chr3",23916804,23920856,"RPL15",6.83,1.63,0.24,-2.07,0.02,"down","yes"]
["chr6",87590135,87667451,"ORC3",2.31,0.54,0.23,-2.11,0.02,"down","yes"]
["chr11",72754730,72793681,"STARD10",4.18,0.98,0.24,-2.09,0.02,"down","yes"]
["chr9",113536504,113597737,"RGS3",2.02,0.47,0.23,-2.11,0.02,"down","yes"]
["chr20",35650326,35664900,"RBM12",1.93,0.46,0.24,-2.07,0.02,"down","yes"]
["chr3",108822698,108855005,"TRAT1",26.01,6.32,0.24,-2.04,0.02,"down","yes"]
["chr11",62789971,62792021,"TMEM223",5.77,1.36,0.24,-2.09,0.02,"down","yes"]
["chr5",54517763,54546585,"SNX18",5.84,1.41,0.24,-2.05,0.02,"down","yes"]
["chr2",171922448,171983682,"HAT1",3.26,0.75,0.23,-2.12,0.02,"down","yes"]
["chr7",98281675,98291524,"BRI3",4.52,1.03,0.23,-2.13,0.02,"down","yes"]
["chr1",23692306,23696418,"RPL11",142.38,34.82,0.24,-2.03,0.02,"down","yes"]
["chr11",5225461,5234466,"HBB",118.9,29.06,0.24,-2.03,0.02,"down","yes"]
["chr19",6413348,6424794,"KHSRP",2.4,0.56,0.24,-2.09,0.02,"down","yes"]
["chr14",31025466,31096450,"AP4S1",1.21,0.28,0.23,-2.1,0.02,"down","yes"]
["chr12",122980721,122982873,"ARL6IP4",2.85,0.65,0.23,-2.13,0.02,"down","yes"]
["chrX",103252995,103255203,"TCEAL8",4.3,1,0.23,-2.11,0.02,"down","yes"]
["chr12",56116599,56117844,"RPL41",63.62,15.6,0.25,-2.03,0.02,"down","yes"]
["chr22",22712280,22906799,"IGLV3-21",10.07,2.42,0.24,-2.06,0.02,"down","yes"]
["chr19",39971170,39981408,"PSMC4",2.83,0.66,0.23,-2.11,0.02,"down","yes"]
["chr7",47964320,47979553,"HUS1",2.76,0.63,0.23,-2.13,0.02,"down","yes"]
["chr17",63773863,63819317,"DDX42",3.26,0.79,0.24,-2.04,0.02,"down","yes"]
["chr19",35904401,35908295,"TYROBP",54.19,13.28,0.25,-2.03,0.02,"down","yes"]
["chr16",681671,684528,"JMJD8",1.61,0.37,0.23,-2.13,0.02,"down","yes"]
["chr10",103088017,103181329,"NT5C2",6.6,1.61,0.24,-2.03,0.02,"down","yes"]
["chr9",83661429,83707934,"UBQLN1",5.02,1.22,0.24,-2.05,0.02,"down","yes"]
["chr17",82458726,82488065,"NARF",4.28,1.01,0.24,-2.08,0.02,"down","yes"]
["chr2",74526648,74529723,"AUP1",3.41,0.81,0.24,-2.08,0.02,"down","yes"]
["chr7",74210006,74229831,"LAT2",44.42,11.01,0.25,-2.01,0.02,"down","yes"]
["chr19",39433207,39435948,"RPS16",921.96,229.42,0.25,-2.01,0.02,"down","yes"]
["chr19",35902480,35904377,"HCST",26.77,6.55,0.24,-2.03,0.02,"down","yes"]
["chr2",64302927,64341703,"AC114752.2",6.13,1.45,0.24,-2.07,0.02,"down","yes"]
["chr16",30069262,30070414,"ALDOA",9.86,2.38,0.24,-2.05,0.02,"down","yes"]
["chrX",55009052,55031062,"ALAS2",18.09,4.48,0.25,-2.01,0.02,"down","yes"]
["chr12",53441741,53475553,"PCBP2",1.71,0.39,0.23,-2.12,0.02,"down","yes"]
["chr2",69789555,69799000,"ANXA4",7.49,1.79,0.24,-2.07,0.02,"down","yes"]
["chr17",79833156,79839429,"CBX4",5.25,1.28,0.24,-2.03,0.02,"down","yes"]
["chr3",157147795,157154666,"CCNL1",1.34,0.32,0.24,-2.08,0.02,"down","yes"]
["chr11",60172020,60178353,"MS4A6A",8.14,1.94,0.24,-2.07,0.03,"down","yes"]
["chr2",127298807,127388004,"MAP3K2",6.49,1.62,0.25,-2,0.03,"down","yes"]
["chr12",48918144,48920963,"CCDC65",6.58,1.52,0.23,-2.11,0.03,"down","yes"]
["chr16",71895553,71929008,"IST1",1.79,0.42,0.24,-2.08,0.03,"down","yes"]
["chr1",32651356,32680040,"RBBP4",8.73,2.15,0.25,-2.02,0.03,"down","yes"]
["chrX",44873177,45112598,"KDM6A",1.12,0.27,0.24,-2.04,0.03,"down","yes"]
["chr19",39834458,39846370,"FBL",53.13,13.31,0.25,-2,0.03,"down","yes"]
["chr20",23374519,23421519,"NAPB",1.23,0.29,0.24,-2.08,0.03,"down","yes"]
["chr6",32844086,32846495,"PSMB8-AS1",3.1,0.72,0.23,-2.1,0.03,"down","yes"]
["chr6",31586217,31588909,"LST1",66.43,16.61,0.25,-2,0.03,"down","yes"]
["chr19",36141303,36146228,"CAPNS1",7.43,1.8,0.24,-2.05,0.03,"down","yes"]
["chr5",131264040,131394556,"CDC42SE2",27.76,6.99,0.25,-1.99,0.03,"down","yes"]
["chr13",27437145,27450164,"MTIF3",5.85,1.39,0.24,-2.07,0.03,"down","yes"]
["chr14",95709968,95714196,"TCL1A",8.04,1.99,0.25,-2.02,0.03,"down","yes"]
["chr1",51789191,51878805,"NRDC",24,6.07,0.25,-1.98,0.03,"down","yes"]
["chr3",197044331,197297204,"DLG1",2.9,0.71,0.25,-2.03,0.03,"down","yes"]
["chr2",215311817,215349763,"ATIC",10.09,2.54,0.25,-1.99,0.03,"down","yes"]
["chr2",230416240,230470489,"SP100",2,0.47,0.24,-2.08,0.03,"down","yes"]
["chr20",64073181,64077530,"RGS19",4,0.98,0.25,-2.03,0.03,"down","yes"]
["chr6",31730583,31736545,"CLIC1",17.26,4.35,0.25,-1.99,0.03,"down","yes"]
["chr1",159009019,159055155,"IFI16",4.22,1.05,0.25,-2,0.03,"down","yes"]
["chr20",54207847,54219953,"PFDN4",5.35,1.33,0.25,-2.01,0.03,"down","yes"]
["chr19",9607332,9621399,"ZNF561",3.44,0.87,0.25,-1.99,0.03,"down","yes"]
["chr8",42836674,42843325,"THAP1",4.35,1.08,0.25,-2.01,0.03,"down","yes"]
["chr2",191678136,191687572,"NABP1",2.47,0.61,0.25,-2.01,0.03,"down","yes"]
["chr7",520391,525232,"HRAT92",1.47,0.36,0.25,-2.02,0.03,"down","yes"]
["chr12",121429777,121580984,"KDM2B",2.03,0.51,0.25,-2,0.03,"down","yes"]
["chrX",68498323,68537285,"YIPF6",1.67,0.42,0.25,-1.99,0.03,"down","yes"]
["chr14",55129044,55145403,"LGALS3",52.79,13.58,0.26,-1.96,0.03,"down","yes"]
["chr3",10300950,10321061,"SEC13",2.49,0.61,0.24,-2.04,0.03,"down","yes"]
["chr14",75016786,75025274,"MLH3",26.14,6.67,0.26,-1.97,0.03,"down","yes"]
["chr3",88149743,88157968,"C3orf38",8.04,2.05,0.26,-1.97,0.03,"down","yes"]
["chr20",4780023,4823645,"RASSF2",31.51,8.14,0.26,-1.95,0.03,"down","yes"]
["chr2",101002293,101006418,"RPL31",42.8,10.99,0.26,-1.96,0.03,"down","yes"]
["chr12",31959438,31992941,"KIAA1551",3.23,0.77,0.24,-2.07,0.03,"down","yes"]
["chr4",112297380,112441371,"ALPK1",1.7,0.42,0.25,-2.01,0.03,"down","yes"]
["chr2",74526645,74529760,"AUP1",9.36,2.39,0.26,-1.97,0.03,"down","yes"]
["chr12",57103273,57105317,"STAT6",2.05,0.5,0.24,-2.05,0.03,"down","yes"]
["chr20",50124044,50153734,"TMEM189",2.05,0.5,0.24,-2.03,0.03,"down","yes"]
["chr1",235109336,235128936,"TOMM20",18.26,4.74,0.26,-1.95,0.03,"down","yes"]
["chr11",119093854,119095467,"H2AFX",4.12,1.03,0.25,-2,0.03,"down","yes"]
["chrX",101009346,101052116,"TRMT2B",1.83,0.46,0.25,-2,0.03,"down","yes"]
["chr14",24136158,24138967,"PSME1",166.3,43.38,0.26,-1.94,0.03,"down","yes"]
["chr8",143816377,143829352,"PUF60",24.25,6.3,0.26,-1.94,0.03,"down","yes"]
["chr16",3065677,3069409,"IL32",7.6,1.87,0.25,-2.03,0.03,"down","yes"]
["chr17",49405073,49414884,"PHB",8.66,2.19,0.25,-1.99,0.03,"down","yes"]
["chr22",23696397,23699168,"RGL4",6.33,1.57,0.25,-2.01,0.03,"down","yes"]
["chr2",70447280,70554015,"TGFA",2.24,0.57,0.25,-1.97,0.03,"down","yes"]
["chr14",75131470,75176631,"TMED10",24.95,6.53,0.26,-1.93,0.03,"down","yes"]
["chr19",4343559,4360072,"MPND",1.91,0.46,0.24,-2.05,0.03,"down","yes"]
["chr22",20917426,20953749,"CRKL",8.73,2.28,0.26,-1.94,0.03,"down","yes"]
["chr8",98041721,98045544,"RPL30",58.43,15.26,0.26,-1.94,0.03,"down","yes"]
["chr11",118339094,118342631,"CD3D",28.8,7.48,0.26,-1.94,0.03,"down","yes"]
["chr16",4461680,4474895,"NMRAL1",5.33,1.37,0.26,-1.96,0.03,"down","yes"]
["chr9",133348218,133350695,"RPL7A",3.39,0.83,0.25,-2.02,0.03,"down","yes"]
["chr15",88636153,88655621,"ISG20",8.73,2.24,0.26,-1.97,0.03,"down","yes"]
["chr9",62801465,62813486,"LINC01410",1.38,0.35,0.25,-2,0.03,"down","yes"]
["chr12",26938497,26960846,"FGFR1OP2",6.8,1.75,0.26,-1.96,0.03,"down","yes"]
["chr22",31104777,31107568,"SELENOM",4.28,1.06,0.25,-2.01,0.03,"down","yes"]
["chr19",38836635,38852338,"HNRNPL",4.7,1.21,0.26,-1.95,0.03,"down","yes"]
["chr9",89358380,89360969,"SECISBP2",8.33,2.09,0.25,-1.99,0.03,"down","yes"]
["chr12",71839759,71923645,"TBC1D15",10.6,2.81,0.27,-1.91,0.03,"down","yes"]
["chr1",153390032,153390976,"S100A8",31.99,8.44,0.26,-1.92,0.03,"down","yes"]
["chrX",149540974,149547034,"CXorf40A",4.06,1.03,0.25,-1.98,0.03,"down","yes"]
["chr19",1576678,1592708,"MBD3",5.06,1.33,0.26,-1.92,0.03,"down","yes"]
["chr14",100291111,100306533,"SLC25A29",2.34,0.6,0.26,-1.96,0.03,"down","yes"]
["chr4",83090688,83109843,"PLAC8",12.81,3.37,0.26,-1.93,0.03,"down","yes"]
["chr12",57694023,57721631,"OS9",7.28,1.94,0.27,-1.91,0.04,"down","yes"]
["chr17",64002632,64020607,"ICAM2",4.5,1.16,0.26,-1.96,0.04,"down","yes"]
["chr2",47818417,47905568,"FBXO11",1.56,0.39,0.25,-1.99,0.04,"down","yes"]
["chr11",72814415,72829633,"ATG16L2",1.65,0.42,0.25,-1.99,0.04,"down","yes"]
["chr10",78033865,78040697,"RPS24",270.44,73.09,0.27,-1.89,0.04,"down","yes"]
["chr9",20820294,20995948,"FOCAD",1.65,0.43,0.26,-1.93,0.04,"down","yes"]
["chr6",31661229,31666283,"GPANK1",3.17,0.83,0.26,-1.93,0.04,"down","yes"]
["chr1",75724351,75763679,"ACADM",2.66,0.7,0.26,-1.93,0.04,"down","yes"]
["chr3",169773427,169787544,"MYNN",3.45,0.91,0.26,-1.92,0.04,"down","yes"]
["chr15",64151717,64157481,"SNX22",1.23,0.31,0.25,-1.97,0.04,"down","yes"]
["chr13",32443697,32538833,"N4BP2L2",2.42,0.63,0.26,-1.95,0.04,"down","yes"]
["chr12",10430609,10435993,"KLRC2",3.57,0.92,0.26,-1.95,0.04,"down","yes"]
["chr5",181236961,181243947,"RACK1",8.61,2.31,0.27,-1.9,0.04,"down","yes"]
["chr9",15470636,15510991,"PSIP1",1.81,0.46,0.25,-1.98,0.04,"down","yes"]
["chr1",12125899,12144207,"TNFRSF8",2.13,0.55,0.26,-1.94,0.04,"down","yes"]
["chr1",26282282,26306636,"UBXN11",4.97,1.33,0.27,-1.9,0.04,"down","yes"]
["chr9",127447674,127451405,"RPL12",845.32,231.93,0.27,-1.87,0.04,"down","yes"]
["chr17",68267026,68291116,"SLC16A6",1.7,0.45,0.26,-1.92,0.04,"down","yes"]
["chr1",154155308,154183172,"TPM3",94.67,26.03,0.27,-1.86,0.04,"down","yes"]
["chr11",64206734,64223882,"FERMT3",3.02,0.8,0.27,-1.91,0.04,"down","yes"]
["chr19",49555711,49580535,"NOSIP",2.24,0.59,0.26,-1.92,0.04,"down","yes"]
["chr6",29888643,29945902,"HLA-A",708.98,195.35,0.28,-1.86,0.04,"down","yes"]
["chr13",45338687,45341158,"TPT1",42.24,11.54,0.27,-1.87,0.04,"down","yes"]
["chr5",139293750,139330002,"MATR3",7.99,2.18,0.27,-1.87,0.04,"down","yes"]
["chr7",75417503,75485976,"POM121C",1.95,0.53,0.27,-1.89,0.04,"down","yes"]
["chr11",8682792,8685848,"RPL27A",12.01,3.17,0.26,-1.92,0.04,"down","yes"]
["chr3",146515955,146544620,"PLSCR1",6.85,1.83,0.27,-1.9,0.04,"down","yes"]
["chr16",30569346,30572734,"ZNF688",2.85,0.77,0.27,-1.9,0.04,"down","yes"]
["chr10",110871795,110900005,"PDCD4",4.92,1.35,0.27,-1.87,0.04,"down","yes"]
["chr19",54200872,54207647,"RPS9",750.9,208.46,0.28,-1.85,0.04,"down","yes"]
["chr2",128145652,128194112,"UGGT1",1.27,0.34,0.27,-1.89,0.04,"down","yes"]
["chr14",24115275,24124029,"DCAF11",1.18,0.31,0.26,-1.95,0.04,"down","yes"]
["chr1",211368929,211374785,"TRAF5",1.62,0.44,0.27,-1.88,0.04,"down","yes"]
["chr2",175178186,175181710,"ATP5G3",3.06,0.81,0.27,-1.91,0.04,"down","yes"]
["chr14",23988822,24006408,"DHRS4L2",2.64,0.7,0.27,-1.91,0.04,"down","yes"]
["chr1",26473206,26475565,"HMGN2",6.08,1.65,0.27,-1.89,0.04,"down","yes"]
["chr2",159712457,159768583,"7-Mar",5.3,1.47,0.28,-1.85,0.04,"down","yes"]
["chrX",49071156,49074071,"PRAF2",3.58,0.96,0.27,-1.9,0.04,"down","yes"]
["chr14",50725827,50830479,"NIN",5.63,1.57,0.28,-1.84,0.04,"down","yes"]
["chrX",154440524,154443465,"GDI1",1.81,0.48,0.27,-1.91,0.04,"down","yes"]
["chr12",53500926,53506431,"TARBP2",2.11,0.56,0.27,-1.92,0.04,"down","yes"]
["chr12",40225011,40304976,"LRRK2",1.18,0.32,0.27,-1.87,0.04,"down","yes"]
["chr12",6200316,6238271,"CD9",2.31,0.6,0.26,-1.94,0.04,"down","yes"]
["chr7",7640776,7879185,"UMAD1",4.47,1.24,0.28,-1.85,0.04,"down","yes"]
["chr6",26445538,26452161,"BTN3A3",2.65,0.7,0.27,-1.92,0.04,"down","yes"]
["chr7",22812632,22822851,"TOMM7",104.36,29.59,0.28,-1.82,0.04,"down","yes"]
["chr6",138773520,138793319,"CCDC28A",4.37,1.2,0.27,-1.87,0.04,"down","yes"]
["chr1",154155304,154183249,"TPM3",5.15,1.44,0.28,-1.83,0.04,"down","yes"]
["chr17",4710634,4721499,"ARRB2",5.39,1.5,0.28,-1.84,0.05,"down","yes"]
["chr14",105736343,105743071,"IGHG1",2.77,0.76,0.28,-1.86,0.05,"down","yes"]
["chr3",39406733,39412059,"RPSA",108.74,31.05,0.29,-1.81,0.05,"down","yes"]
["chr2",113890598,113957591,"ACTR3",5.66,1.58,0.28,-1.84,0.05,"down","yes"]
["chr2",86143932,86195770,"IMMT",4.13,1.16,0.28,-1.83,0.05,"down","yes"]
["chr17",82051958,82057470,"GPS1",3.46,0.96,0.28,-1.85,0.05,"down","yes"]
["chr19",13104939,13116725,"TRMT1",1.96,0.53,0.27,-1.89,0.05,"down","yes"]
["chr19",51964343,51986826,"ZNF350",3.72,1.04,0.28,-1.84,0.05,"down","yes"]
["chr1",31296995,31364936,"ZCCHC17",9.32,2.63,0.28,-1.83,0.05,"down","yes"]
["chr1",1785286,1848029,"GNB1",8.81,2.51,0.28,-1.81,0.05,"down","yes"]
["chr15",74899992,74906837,"FAM219B",1.05,0.28,0.27,-1.92,0.05,"down","yes"]
["chr22",31496139,31618551,"SFI1",1.05,0.28,0.27,-1.88,0.05,"down","yes"]
["chr5",86617928,86620766,"COX7C",31.25,8.86,0.28,-1.82,0.05,"down","yes"]
["chr1",21219859,21290489,"ECE1",10.79,3.08,0.29,-1.81,0.05,"down","yes"]
["chr6",73515752,73521032,"EEF1A1",251.01,72.47,0.29,-1.79,0.05,"down","yes"]
["chr6",158765748,158819412,"EZR",25.08,7.23,0.29,-1.79,0.05,"down","yes"]
["chr11",18396554,18407281,"LDHA",3.05,0.83,0.27,-1.87,0.05,"down","yes"]
["chr11",64764606,64778730,"SF1",4.89,1.4,0.29,-1.81,0.05,"down","yes"]
["chr14",105741338,105743071,"IGHG1",4.91,1.37,0.28,-1.84,0.05,"down","yes"]
["chr11",560956,564012,"RASSF7",6.5,1.87,0.29,-1.8,0.05,"down","yes"]
["chr15",69453019,69455546,"RPLP1",4.14,1.14,0.28,-1.86,0.05,"down","yes"]
["chr14",103385985,103503245,"MARK3",5.31,1.52,0.29,-1.8,0.05,"down","yes"]
["chr19",39406813,39409412,"ZFP36",38.15,11.12,0.29,-1.78,0.05,"down","yes"]
["chr16",784974,787981,"RPUSD1",3.36,0.95,0.28,-1.82,0.05,"down","yes"]
["chr5",151029947,151081084,"TNIP1",3.79,1.09,0.29,-1.8,0.05,"down","yes"]
["chr1",151156629,151159757,"SCNM1",14.28,4.13,0.29,-1.79,0.05,"down","yes"]
["chr11",61964566,61967631,"FTH1",29.52,8.58,0.29,-1.78,0.05,"down","yes"]
["chr19",47130859,47210191,"SAE1",2.41,0.68,0.28,-1.83,0.05,"down","yes"]
["chr1",150621251,150629596,"ENSA",31.29,9.15,0.29,-1.77,0.05,"down","yes"]
["chr1",248850006,248859072,"ZNF692",3.13,0.89,0.28,-1.82,0.05,"down","yes"]
["chr1",154272629,154275875,"HAX1",4.25,1.21,0.28,-1.82,0.05,"down","yes"]
["chr3",42784298,42804531,"HIGD1A",26.55,7.77,0.29,-1.77,0.05,"down","yes"]
["chr19",55655065,55674298,"U2AF2",15.89,4.64,0.29,-1.78,0.05,"down","yes"]
["chr14",101809895,101912625,"PPP2R5C",12.18,3.55,0.29,-1.78,0.05,"down","yes"]
["chr8",94925972,94949366,"TP53INP1",6.26,1.84,0.29,-1.77,0.05,"down","yes"]
["chr12",57472270,57478198,"ARHGAP9",10.03,2.93,0.29,-1.77,0.05,"down","yes"]
["chrX",103675496,103688064,"MORF4L2",4.19,1.2,0.29,-1.8,0.05,"down","yes"]
["chr7",127588413,127591112,"ARF5",12.58,3.6,0.29,-1.8,0.05,"down","yes"]
["chr1",26787995,26798398,"PIGV",2.12,0.6,0.28,-1.83,0.05,"down","yes"]
["chr14",20469379,20477094,"PNP",42,12.38,0.29,-1.76,0.05,"down","yes"]
["chr2",190435895,190502315,"MFSD6",2.55,0.74,0.29,-1.78,0.05,"down","yes"]
["chr1",173863901,173867043,"GAS5",25.43,7.44,0.29,-1.77,0.05,"down","yes"]
["chr9",113221562,113264492,"SLC31A1",4.08,1.2,0.29,-1.77,0.05,"down","yes"]

{"sheet":"Table 8","index":7,"n_rows":114144,"n_cols":24,"rows_kept":2250,"cut":true,"bounds":{"rows_first":1000,"rows_last":250,"rows_between":1000,"halvings":1}}
["t_id","class_code","chr","strand","start","end","t_name","num_exons","length","gene_id","gene_name","GO","KEGG","KO_ENTRY","EC","Description","FPKM.T4","FPKM.T3","fc","log2(fc)","pval","qval","regulation","significant"]
[124473,"j","chr20","-",48624249,48827769,"MSTRG.9804.1",41,7149,"MSTRG.9804","PREX1","NA","NA","NA","NA","NA",{"v":0.199711,"d":"0.20"},{"v":32.880245,"d":"32.88"},{"v":0.00607389026450381,"d":"0.01"},{"v":-7.36316344074122,"d":"-7.36"},{"v":2.74158294642257e-17,"d":"0.00"},{"v":5.47439282741658E-13,"d":"0.00"},"down","yes"]
[2839,0,"chr1","-",24899511,24965010,"ENST00000399916",6,4340,"MSTRG.249","RUNX3","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0043231(intracellular membrane-bounded organelle);GO:0005524(ATP binding);GO:0005730(nucleolus);GO:0005829(cytosol);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0005515(protein binding);GO:0045893(positive regulation of transcription, DNA-templated);GO:0005654(nucleoplasm);GO:0000981(RNA polymerase II transcription factor activity, sequence-specific DNA binding);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0045786(negative regulation of cell cycle);GO:0000790(nuclear chromatin);GO:0006366(transcription from RNA polymerase II promoter);GO:0006468(protein phosphorylation);GO:0000977(RNA polymerase II regulatory region sequence-specific DNA binding);GO:0050680(negative regulation of epithelial cell proliferation);GO:0030097(hemopoiesis);GO:0048935(peripheral nervous system neuron development);GO:0001503(ossification);GO:0002062(chondrocyte differentiation);GO:0071559(response to transforming growth factor beta);GO:0045595(regulation of cell differentiation)","04658(Th1 and Th2 cell differentiation)","K09279","NA","runt related transcription factor 3 [Source:HGNC Symbol;Acc:HGNC:10473]",{"v":27.753008,"d":"27.75"},{"v":0.199047,"d":"0.20"},{"v":139.42942119198,"d":"139.43"},{"v":7.12339120814876,"d":"7.12"},{"v":8.27673632929501e-17,"d":"0.00"},{"v":8.26349355116814E-13,"d":"0.00"},"up","yes"]
[95091,0,"chr19","-",4445007,4449604,"ENST00000588238",1,4598,"MSTRG.7681","UBXN6","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005765(lysosomal membrane);GO:0005829(cytosol);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0005815(microtubule organizing center);GO:0031902(late endosome membrane);GO:0003674(molecular_function);GO:0008150(biological_process);GO:0070062(extracellular exosome);GO:0043234(protein complex);GO:0031901(early endosome membrane);GO:0019898(extrinsic component of membrane);GO:0032510(endosome to lysosome transport via multivesicular body sorting pathway);GO:0016236(macroautophagy);GO:0036503(ERAD pathway)","04141(Protein processing in endoplasmic reticulum)","NA","NA","UBX domain protein 6 [Source:HGNC Symbol;Acc:HGNC:14928]",{"v":0.501979,"d":"0.50"},{"v":49.103035,"d":"49.10"},{"v":0.0102229729791651,"d":"0.01"},{"v":-6.61204137720044,"d":"-6.61"},{"v":3.80320451080915e-15,"d":"0.00"},{"v":1.97633407180554e-11,"d":"0.00"},"down","yes"]
[36323,0,"chr11","-",123057497,123061332,"ENST00000227378",8,2186,"MSTRG.2940","HSPA8","GO:0003723(RNA binding);GO:0006397(mRNA processing);GO:0008380(RNA splicing);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0030529(intracellular ribonucleoprotein complex);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0005681(spliceosomal complex);GO:0042470(melanosome);GO:0005615(extracellular space);GO:0098793(presynapse);GO:0005730(nucleolus);GO:0005925(focal adhesion);GO:0005576(extracellular region);GO:0006986(response to unfolded protein);GO:0005654(nucleoplasm);GO:0045296(cadherin binding);GO:0070062(extracellular exosome);GO:0005622(intracellular);GO:0061024(membrane organization);GO:0072562(blood microparticle);GO:0043488(regulation of mRNA stability);GO:0016032(viral process);GO:0031012(extracellular matrix);GO:0006457(protein folding);GO:0043312(neutrophil degranulation);GO:0016887(ATPase activity);GO:0034774(secretory granule lumen);GO:1904813(ficolin-1-rich granule lumen);GO:0045892(negative regulation of transcription, DNA-templated);GO:0051082(unfolded protein binding);GO:0019899(enzyme binding);GO:0007269(neurotransmitter secretion);GO:0000398(mRNA splicing, via spliceosome);GO:0031625(ubiquitin protein ligase binding);GO:0000151(ubiquitin ligase complex);GO:1900034(regulation of cellular response to heat);GO:0042623(ATPase activity, coupled);GO:0001664(G-protein coupled receptor binding);GO:0031647(regulation of protein stability);GO:0006479(protein methylation);GO:0042026(protein refolding);GO:0031072(heat shock protein binding);GO:0023026(MHC class II protein complex binding);GO:0046034(ATP metabolic process);GO:0043254(regulation of protein complex assembly);GO:0061684(chaperone-mediated autophagy);GO:0043202(lysosomal lumen);GO:0055131(C3HC4-type RING finger domain binding);GO:0098575(lumenal side of lysosomal membrane);GO:0009267(cellular response to starvation);GO:0061635(regulation of protein complex stability);GO:0061740(protein targeting to lysosome involved in chaperone-mediated autophagy);GO:0061741(chaperone-mediated protein transport involved in chaperone-mediated autophagy);GO:1902904(negative regulation of supramolecular fiber organization);GO:1904589(regulation of protein import);GO:1904764(chaperone-mediated autophagy translocation complex disassembly);GO:0000974(Prp19 complex);GO:0005765(lysosomal membrane);GO:0061202(clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane);GO:0001786(phosphatidylserine binding);GO:0044788(modulation by host of viral process);GO:0044829(positive regulation by host of viral genome replication);GO:0048026(positive regulation of mRNA splicing, via spliceosome);GO:0051085(chaperone mediated protein folding requiring cofactor);GO:0051726(regulation of cell cycle);GO:0061738(late endosomal microautophagy);GO:0072318(clathrin coat disassembly);GO:0005770(late endosome);GO:0043209(myelin sheath)","03040(Spliceosome);04141(Protein processing in endoplasmic reticulum);04010(MAPK signaling pathway);04144(Endocytosis);04612(Antigen processing and presentation);04915(Estrogen signaling pathway);04213(Longevity regulating pathway - multiple species);05134(Legionellosis);05162(Measles);05164(Influenza A);05169(Epstein-Barr virus infection);05145(Toxoplasmosis)","K03283","NA","heat shock protein family A (Hsp70) member 8 [Source:HGNC Symbol;Acc:HGNC:5241]",{"v":39.360733,"d":"39.36"},{"v":0.430532,"d":"0.43"},{"v":91.4234783941728,"d":"91.42"},{"v":6.51449280517209,"d":"6.51"},{"v":4.79976883876512E-15,"d":"0.00"},{"v":1.97633407180554e-11,"d":"0.00"},"up","yes"]
[100455,"j","chr19","+",36139631,36150356,"MSTRG.8090.2",12,1515,"MSTRG.8090","CAPNS1","NA","NA","NA","NA","NA",{"v":53.833305,"d":"53.83"},{"v":0.583487,"d":"0.58"},{"v":92.2613614356447,"d":"92.26"},{"v":6.52765467627816,"d":"6.53"},{"v":4.94875318460923e-15,"d":"0.00"},{"v":1.97633407180554e-11,"d":"0.00"},"up","yes"]
[4155,"j","chr1","-",35176372,35193148,"MSTRG.405.2",12,8871,"MSTRG.405","SFPQ","NA","NA","NA","NA","NA",{"v":6.937781,"d":"6.94"},{"v":0.08414,"d":"0.08"},{"v":82.4552056096981,"d":"82.46"},{"v":6.36553867248249,"d":"6.37"},{"v":1.73057265293197e-14,"d":"0.00"},{"v":5.75934578895761e-11,"d":"0.00"},"up","yes"]
[59501,"j","chr14","-",105703995,105863312,"MSTRG.4749.13",6,1424,"MSTRG.4749","IGHA1","NA","NA","NA","NA","NA",{"v":230.96579,"d":"230.97"},{"v":3.099991,"d":"3.10"},{"v":74.5053098541254,"d":"74.51"},{"v":6.21927134230422,"d":"6.22"},{"v":2.19346490691442e-14,"d":"0.00"},{"v":6.25701532303815e-11,"d":"0.00"},"up","yes"]
[110493,0,"chr2","+",68774801,68826833,"ENST00000409220",10,2939,"MSTRG.8782","ARHGAP25","GO:0007165(signal transduction);GO:0043547(positive regulation of GTPase activity);GO:0005096(GTPase activator activity);GO:0005829(cytosol);GO:0051056(regulation of small GTPase mediated signal transduction)","NA","NA","NA","Rho GTPase activating protein 25 [Source:HGNC Symbol;Acc:HGNC:28951]",{"v":0.330696,"d":"0.33"},{"v":27.279926,"d":"27.28"},{"v":0.0121223202731562,"d":"0.01"},{"v":-6.36619032543611,"d":"-6.37"},{"v":3.15867496231983e-14,"d":"0.00"},{"v":7.8840527059503e-11,"d":"0.00"},"down","yes"]
[75631,"j","chr16","-",74447589,74607097,"MSTRG.6132.2",28,7404,"MSTRG.6132","GLG1","NA","NA","NA","NA","NA",{"v":10.208087,"d":"10.21"},{"v":0.138568,"d":"0.14"},{"v":73.6684299405346,"d":"73.67"},{"v":6.20297459038096,"d":"6.20"},{"v":3.81176276363908e-14,"d":"0.00"},{"v":8.45703098492723e-11,"d":"0.00"},"up","yes"]
[125863,0,"chr21","-",8210384,8211306,"ENST00000631211",1,923,"MSTRG.9928","FP671120.3","NA","NA","NA","NA","NA",{"v":79.968109,"d":"79.97"},{"v":1.278632,"d":"1.28"},{"v":62.5419268405608,"d":"62.54"},{"v":5.96675176251136,"d":"5.97"},{"v":1.82601038503292E-13,"d":"0.00"},{"v":3.64617753683374e-10,"d":"0.00"},"up","yes"]
[8496,0,"chr1","+",101236888,101241518,"ENST00000305352",2,2909,"MSTRG.734","S1PR1","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0043231(intracellular membrane-bounded organelle);GO:0004930(G-protein coupled receptor activity);GO:0007186(G-protein coupled receptor signaling pathway);GO:0005654(nucleoplasm);GO:0005886(plasma membrane);GO:0004871(signal transducer activity);GO:0007165(signal transduction);GO:0038036(sphingosine-1-phosphate receptor activity);GO:0045121(membrane raft);GO:0006935(chemotaxis);GO:0005768(endosome);GO:0030500(regulation of bone mineralization);GO:0072678(T cell migration);GO:0007155(cell adhesion);GO:0031226(intrinsic component of plasma membrane);GO:0030032(lamellipodium assembly);GO:0001664(G-protein coupled receptor binding);GO:0016477(cell migration);GO:0001525(angiogenesis);GO:0031532(actin cytoskeleton reorganization);GO:0003376(sphingosine-1-phosphate signaling pathway);GO:0045124(regulation of bone resorption);GO:0001955(blood vessel maturation);GO:0046625(sphingolipid binding);GO:0003245(cardiac muscle tissue growth involved in heart morphogenesis);GO:0007193(adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway);GO:0007420(brain development);GO:0008284(positive regulation of cell proliferation);GO:0019226(transmission of nerve impulse);GO:0030155(regulation of cell adhesion);GO:0030182(neuron differentiation);GO:0030335(positive regulation of cell migration);GO:0030595(leukocyte chemotaxis);GO:0043547(positive regulation of GTPase activity);GO:0045446(endothelial cell differentiation);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0048661(positive regulation of smooth muscle cell proliferation);GO:0050927(positive regulation of positive chemotaxis);GO:0051482(positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway);GO:0051497(negative regulation of stress fiber assembly);GO:0061384(heart trabecula morphogenesis);GO:0009897(external side of plasma membrane)","04068(FoxO signaling pathway);04071(Sphingolipid signaling pathway);04080(Neuroactive ligand-receptor interaction)","K04288","NA","sphingosine-1-phosphate receptor 1 [Source:HGNC Symbol;Acc:HGNC:3165]",{"v":43.757202,"d":"43.76"},{"v":0.757731,"d":"0.76"},{"v":57.7476729868515,"d":"57.75"},{"v":5.85169090742525,"d":"5.85"},{"v":3.0570463509817e-13,"d":"0.00"},{"v":5.54937286694569e-10,"d":"0.00"},"up","yes"]
[25827,"s","chr11","+",5225461,5234569,"MSTRG.2146.1",4,518,"MSTRG.2146","HBB","NA","NA","NA","NA","NA",{"v":32.600719,"d":"32.60"},{"v":1941.313354,"d":"1941.31"},{"v":0.0167931256089222,"d":"0.02"},{"v":-5.89598541388808,"d":"-5.90"},{"v":3.64957175864929e-13,"d":"0.00"},{"v":5.55805085160724e-10,"d":"0.00"},"down","yes"]
[156913,"j","chr5","+",96663053,96776973,"MSTRG.12236.17",32,3185,"MSTRG.12236","CAST","NA","NA","NA","NA","NA",{"v":15.74956,"d":"15.75"},{"v":0.266232,"d":"0.27"},{"v":59.1572763604676,"d":"59.16"},{"v":5.88648372623407,"d":"5.89"},{"v":3.82174857807624e-13,"d":"0.00"},{"v":5.55805085160724e-10,"d":"0.00"},"up","yes"]
[58491,0,"chr14","-",100333788,100375644,"ENST00000392882",11,2938,"MSTRG.4676","WARS","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0006412(translation);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0005829(cytosol);GO:0016874(ligase activity);GO:0005515(protein binding);GO:0004812(aminoacyl-tRNA ligase activity);GO:0004830(tryptophan-tRNA ligase activity);GO:0006418(tRNA aminoacylation for protein translation);GO:0006436(tryptophanyl-tRNA aminoacylation);GO:0070062(extracellular exosome);GO:0043234(protein complex);GO:0019904(protein domain specific binding);GO:0001525(angiogenesis);GO:0008285(negative regulation of cell proliferation);GO:0042803(protein homodimerization activity);GO:0045765(regulation of angiogenesis);GO:0010628(positive regulation of gene expression);GO:0010835(regulation of protein ADP-ribosylation);GO:0031334(positive regulation of protein complex assembly);GO:0019901(protein kinase binding);GO:0019210(kinase inhibitor activity);GO:0001933(negative regulation of protein phosphorylation);GO:0006469(negative regulation of protein kinase activity)","00970(Aminoacyl-tRNA biosynthesis)","K01867","EC:6.1.1.2","tryptophanyl-tRNA synthetase [Source:HGNC Symbol;Acc:HGNC:12729]",{"v":0.449233,"d":"0.45"},{"v":27.987507,"d":"27.99"},{"v":0.0160511974146179,"d":"0.02"},{"v":-5.96117526378578,"d":"-5.96"},{"v":3.89687058906758e-13,"d":"0.00"},{"v":5.55805085160724e-10,"d":"0.00"},"down","yes"]
[125886,0,"chr21","-",8437629,8438551,"ENST00000627981",1,923,"MSTRG.9941","FP236383.3","NA","NA","NA","NA","NA",{"v":100.740288,"d":"100.74"},{"v":1.784012,"d":"1.78"},{"v":56.4683914682188,"d":"56.47"},{"v":5.81937163086611,"d":"5.82"},{"v":4.25939419462402E-13,"d":"0.00"},{"v":5.6701055518835e-10,"d":"0.00"},"up","yes"]
[111985,0,"chr2","-",86784610,86791680,"ENST00000283635",6,2873,"MSTRG.8886","CD8A","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005886(plasma membrane);GO:0005576(extracellular region);GO:0006955(immune response);GO:0002376(immune system process);GO:0002250(adaptive immune response);GO:0050776(regulation of immune response);GO:0005887(integral component of plasma membrane);GO:0005515(protein binding);GO:0007166(cell surface receptor signaling pathway);GO:0042110(T cell activation);GO:0007169(transmembrane receptor protein tyrosine kinase signaling pathway);GO:0042288(MHC class I protein binding);GO:0015026(coreceptor activity);GO:0009897(external side of plasma membrane);GO:0042101(T cell receptor complex);GO:0002456(T cell mediated immunity);GO:0019882(antigen processing and presentation);GO:0045065(cytotoxic T cell differentiation);GO:0044853(plasma membrane raft);GO:0019901(protein kinase binding);GO:0042803(protein homodimerization activity);GO:0050850(positive regulation of calcium-mediated signaling);GO:0051607(defense response to virus);GO:0009986(cell surface)","04514(Cell adhesion molecules (CAMs));04640(Hematopoietic cell lineage);04612(Antigen processing and presentation);04660(T cell receptor signaling pathway);05340(Primary immunodeficiency)","K06458","NA","CD8a molecule [Source:HGNC Symbol;Acc:HGNC:1706]",{"v":0.225562,"d":"0.23"},{"v":14.082996,"d":"14.08"},{"v":0.0160166203270952,"d":"0.02"},{"v":-5.96428643352183,"d":"-5.96"},{"v":5.94797608353953e-13,"d":"0.00"},{"v":7.42307415225733E-10,"d":"0.00"},"down","yes"]
[160512,0,"chr5","-",157477304,157575775,"ENST00000257527",23,6481,"MSTRG.12509","ADAM19","GO:0016021(integral component of membrane);GO:0017124(SH3 domain binding);GO:0006508(proteolysis);GO:0005794(Golgi apparatus);GO:0004222(metalloendopeptidase activity);GO:0008237(metallopeptidase activity);GO:0006509(membrane protein ectodomain proteolysis);GO:0016020(membrane);GO:0046872(metal ion binding);GO:0016787(hydrolase activity);GO:0008233(peptidase activity);GO:0005886(plasma membrane);GO:0030198(extracellular matrix organization);GO:0007507(heart development)","NA","NA","NA","ADAM metallopeptidase domain 19 [Source:HGNC Symbol;Acc:HGNC:197]",{"v":0.304086,"d":"0.30"},{"v":17.420336,"d":"17.42"},{"v":0.0174558056744715,"d":"0.02"},{"v":-5.84014924361221,"d":"-5.84"},{"v":7.47997576052685e-13,"d":"0.00"},{"v":8.23312061774214e-10,"d":"0.00"},"down","yes"]
[130980,"j","chr22","-",37225261,37244432,"MSTRG.10429.1",8,1557,"MSTRG.10429","RAC2","NA","NA","NA","NA","NA",{"v":2.096978,"d":"2.10"},{"v":118.102676,"d":"118.10"},{"v":0.0177555502637383,"d":"0.02"},{"v":-5.81558611804074,"d":"-5.82"},{"v":7.64594917776157e-13,"d":"0.00"},{"v":8.23312061774214e-10,"d":"0.00"},"down","yes"]
[148177,"j","chr4","-",73980183,73988283,"MSTRG.11659.2",6,2066,"MSTRG.11659","PPBP","NA","NA","NA","NA","NA",{"v":32.554668,"d":"32.55"},{"v":0.612568,"d":"0.61"},{"v":53.1445782345797,"d":"53.14"},{"v":5.73185061160958,"d":"5.73"},{"v":7.8339989852314e-13,"d":"0.00"},{"v":8.23312061774214e-10,"d":"0.00"},"up","yes"]
[33684,0,"chr11","+",83156988,83187451,"ENST00000298281",16,7677,"MSTRG.2775","PCF11","GO:0006397(mRNA processing);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005739(mitochondrion);GO:0005737(cytoplasm);GO:0003729(mRNA binding);GO:0006378(mRNA polyadenylation);GO:0005849(mRNA cleavage factor complex);GO:0006369(termination of RNA polymerase II transcription);GO:0031124(mRNA 3'-end processing);GO:0000398(mRNA splicing, via spliceosome);GO:0000993(RNA polymerase II core binding);GO:0006379(mRNA cleavage)","03015(mRNA surveillance pathway)","K14400","NA","PCF11 cleavage and polyadenylation factor subunit [Source:HGNC Symbol;Acc:HGNC:30097]",{"v":5.504624,"d":"5.50"},{"v":0.104798,"d":"0.10"},{"v":52.5260405732934,"d":"52.53"},{"v":5.71496093274827,"d":"5.71"},{"v":1.17268198347655E-12,"d":"0.00"},{"v":1.17080569230298e-09,"d":"0.00"},"up","yes"]
[162525,0,"chr6","+",4021267,4064982,"ENST00000480058",16,6775,"MSTRG.12644","PRPF4B","GO:0003723(RNA binding);GO:0006397(mRNA processing);GO:0008380(RNA splicing);GO:0005634(nucleus);GO:0016607(nuclear speck);GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0005515(protein binding);GO:0005681(spliceosomal complex);GO:0000398(mRNA splicing, via spliceosome);GO:0071013(catalytic step 2 spliceosome);GO:0005694(chromosome)","NA","NA","NA","pre-mRNA processing factor 4B [Source:HGNC Symbol;Acc:HGNC:17346]",{"v":5.170003,"d":"5.17"},{"v":0.101005,"d":"0.10"},{"v":51.185614573536,"d":"51.19"},{"v":5.67766650082525,"d":"5.68"},{"v":1.63325999180122e-12,"d":"0.00"},{"v":1.49789563831395e-09,"d":"0.00"},"up","yes"]
[137944,"j","chr3","+",69079202,69106128,"MSTRG.11046.1",5,2387,"MSTRG.11046","ARL6IP5","NA","NA","NA","NA","NA",{"v":0.36628,"d":"0.37"},{"v":20.222786,"d":"20.22"},{"v":0.0181122422993548,"d":"0.02"},{"v":-5.7868910264846,"d":"-5.79"},{"v":1.71557722319342E-12,"d":"0.00"},{"v":1.49789563831395e-09,"d":"0.00"},"down","yes"]
[61878,0,"chr15","+",43792337,43796089,"ENST00000445816",4,2099,"MSTRG.5031","SERF2","GO:0005634(nucleus);GO:0005829(cytosol);GO:0003674(molecular_function);GO:0008150(biological_process)","NA","NA","NA","small EDRK-rich factor 2 [Source:HGNC Symbol;Acc:HGNC:10757]",{"v":23.466475,"d":"23.47"},{"v":0.470654,"d":"0.47"},{"v":49.8592915390074,"d":"49.86"},{"v":5.63979047830999,"d":"5.64"},{"v":1.72534052890729e-12,"d":"0.00"},{"v":1.49789563831395e-09,"d":"0.00"},"up","yes"]
[59492,"j","chr14","-",105643142,105864265,"MSTRG.4749.10",5,2109,"MSTRG.4749","IGHG2","NA","NA","NA","NA","NA",{"v":0.437934,"d":"0.44"},{"v":23.198038,"d":"23.20"},{"v":0.018878062015417,"d":"0.02"},{"v":-5.7271455216986,"d":"-5.73"},{"v":2.15000891426201E-12,"d":"0.00"},{"v":1.78880741666599e-09,"d":"0.00"},"down","yes"]
[90255,"j","chr18","+",2847195,2916531,"MSTRG.7383.2",11,4953,"MSTRG.7383","EMILIN2","NA","NA","NA","NA","NA",{"v":0.210494,"d":"0.21"},{"v":10.625346,"d":"10.63"},{"v":0.0198105548751071,"d":"0.02"},{"v":-5.65758690044311,"d":"-5.66"},{"v":3.51026608936109E-12,"d":"0.00"},{"v":2.80371973089449e-09,"d":"0.00"},"down","yes"]
[196822,0,"chrX","-",47624214,47630305,"ENST00000247153",10,1713,"MSTRG.15263","CFP","GO:0005576(extracellular region);GO:0002376(immune system process);GO:0045087(innate immune response);GO:0006956(complement activation);GO:0030449(regulation of complement activation);GO:0031012(extracellular matrix);GO:0043312(neutrophil degranulation);GO:0006955(immune response);GO:0005615(extracellular space);GO:0005788(endoplasmic reticulum lumen);GO:0035580(specific granule lumen);GO:1904724(tertiary granule lumen);GO:0042742(defense response to bacterium);GO:0006957(complement activation, alternative pathway);GO:0036066(protein O-linked fucosylation)","05168(Herpes simplex infection)","K15412","NA","complement factor properdin [Source:HGNC Symbol;Acc:HGNC:8864]",{"v":0.415628,"d":"0.42"},{"v":21.134474,"d":"21.13"},{"v":0.0196658786019468,"d":"0.02"},{"v":-5.66816154753885,"d":"-5.67"},{"v":4.30886103997441e-12,"d":"0.00"},{"v":3.30920527870035E-9,"d":"0.00"},"down","yes"]
[11440,0,"chr1","-",154582062,154608206,"ENST00000368474",15,6625,"MSTRG.1019","ADAR","GO:0003723(RNA binding);GO:0006396(RNA processing);GO:0006397(mRNA processing);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0046872(metal ion binding);GO:0005730(nucleolus);GO:0005654(nucleoplasm);GO:0016787(hydrolase activity);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0002376(immune system process);GO:0045087(innate immune response);GO:0031047(gene silencing by RNA);GO:0051607(defense response to virus);GO:0004000(adenosine deaminase activity);GO:0009615(response to virus);GO:0003726(double-stranded RNA adenosine deaminase activity);GO:0060337(type I interferon signaling pathway);GO:0045070(positive regulation of viral genome replication);GO:0044387(negative regulation of protein kinase activity by regulation of protein phosphorylation);GO:0035455(response to interferon-alpha);GO:0044530(supraspliceosomal complex);GO:0001649(osteoblast differentiation);GO:0001701(in utero embryonic development);GO:0002244(hematopoietic progenitor cell differentiation);GO:0002566(somatic diversification of immune receptors via somatic mutation);GO:0006382(adenosine to inosine editing);GO:0016553(base conversion or substitution editing);GO:0030218(erythrocyte differentiation);GO:0031054(pre-miRNA processing);GO:0035196(production of miRNAs involved in gene silencing by miRNA);GO:0035280(miRNA loading onto RISC involved in gene silencing by miRNA);GO:0043066(negative regulation of apoptotic process);GO:0045071(negative regulation of viral genome replication);GO:0060216(definitive hemopoiesis);GO:0060339(negative regulation of type I interferon-mediated signaling pathway);GO:0061484(hematopoietic stem cell homeostasis);GO:0098586(cellular response to virus);GO:1900369(negative regulation of RNA interference)","04623(Cytosolic DNA-sensing pathway);05162(Measles);05164(Influenza A)","K12968","EC:3.5.4.37","adenosine deaminase, RNA specific [Source:HGNC Symbol;Acc:HGNC:225]",{"v":0.43152,"d":"0.43"},{"v":19.422792,"d":"19.42"},{"v":0.0222171971980136,"d":"0.02"},{"v":-5.49217936420768,"d":"-5.49"},{"v":6.86078366500001e-12,"d":"0.00"},{"v":5.04762772771563e-09,"d":"0.00"},"down","yes"]
[83661,"j","chr17","-",42700431,42745054,"MSTRG.6845.4",20,5269,"MSTRG.6845","EZH1","NA","NA","NA","NA","NA",{"v":0.155526,"d":"0.16"},{"v":7.41044,"d":"7.41"},{"v":0.0209874177511727,"d":"0.02"},{"v":-5.57433151846389,"d":"-5.57"},{"v":7.07800362460124E-12,"d":"0.00"},{"v":5.04762772771563e-09,"d":"0.00"},"down","yes"]
[78653,"j","chr17","-",7240014,7251965,"MSTRG.6385.1",11,4452,"MSTRG.6385","CTDNEP1","NA","NA","NA","NA","NA",{"v":2.074058,"d":"2.07"},{"v":89.588692,"d":"89.59"},{"v":0.0231508905164058,"d":"0.02"},{"v":-5.43278850087268,"d":"-5.43"},{"v":8.53500083159377e-12,"d":"0.00"},{"v":5.87678953811256e-09,"d":"0.00"},"down","yes"]
[115404,"j","chr2","-",152655683,152717831,"MSTRG.9173.3",27,3615,"MSTRG.9173","PRPF40A","NA","NA","NA","NA","NA",{"v":8.465219,"d":"8.47"},{"v":0.195698,"d":"0.20"},{"v":43.2565432452043,"d":"43.26"},{"v":5.43484647488304,"d":"5.43"},{"v":9.46761561094127e-12,"d":"0.00"},{"v":6.30164495064251e-09,"d":"0.00"},"up","yes"]
[67289,"s","chr16","-",172889,177137,"MSTRG.5479.2",3,327,"MSTRG.5479","HBA2","NA","NA","NA","NA","NA",{"v":42.61425,"d":"42.61"},{"v":1776.256104,"d":"1776.26"},{"v":0.0239910505608036,"d":"0.02"},{"v":-5.3813598555833,"d":"-5.38"},{"v":1.13517099572907E-11,"d":"0.00"},{"v":7.31196594926389e-09,"d":"0.00"},"down","yes"]
[156912,0,"chr5","+",96663053,96772692,"ENST00000508608",31,2425,"MSTRG.12236","CAST","GO:0003723(RNA binding);GO:0005783(endoplasmic reticulum);GO:0005829(cytosol);GO:0005515(protein binding);GO:0004869(cysteine-type endopeptidase inhibitor activity);GO:0030414(peptidase inhibitor activity);GO:0010466(negative regulation of peptidase activity);GO:0045296(cadherin binding);GO:0004866(endopeptidase inhibitor activity);GO:0016020(membrane);GO:2000675(negative regulation of type B pancreatic cell apoptotic process);GO:0010859(calcium-dependent cysteine-type endopeptidase inhibitor activity);GO:0097340(inhibition of cysteine-type endopeptidase activity)","NA","NA","NA","calpastatin [Source:HGNC Symbol;Acc:HGNC:1515]",{"v":0.36514,"d":"0.37"},{"v":16.091021,"d":"16.09"},{"v":0.0226921585647051,"d":"0.02"},{"v":-5.46166233957999,"d":"-5.46"},{"v":1.315995969817e-11,"d":"0.00"},{"v":8.21181485165808e-09,"d":"0.00"},"down","yes"]
[89772,"j","chr17","+",82228445,82240086,"MSTRG.7355.4",5,2619,"MSTRG.7355","SLC16A3","NA","NA","NA","NA","NA",{"v":0.471109,"d":"0.47"},{"v":19.87607,"d":"19.88"},{"v":0.0237023214347706,"d":"0.02"},{"v":-5.39882782438886,"d":"-5.40"},{"v":1.74665148685215E-11,"d":"0.00"},{"v":1.05688293604435e-08,"d":"0.00"},"down","yes"]
[36847,0,"chr11","-",128460244,128522201,"ENST00000526145",7,3389,"MSTRG.2965","ETS1","GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0005634(nucleus);GO:0050729(positive regulation of inflammatory response);GO:1904996(positive regulation of leukocyte adhesion to vascular endothelial cell);GO:0005737(cytoplasm);GO:0005654(nucleoplasm);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0043565(sequence-specific DNA binding);GO:0005515(protein binding);GO:0002376(immune system process);GO:0042802(identical protein binding);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:0006955(immune response);GO:0008134(transcription factor binding);GO:0045893(positive regulation of transcription, DNA-templated);GO:0000982(transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0001077(transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0008285(negative regulation of cell proliferation);GO:0010595(positive regulation of endothelial cell migration);GO:0045765(regulation of angiogenesis);GO:0048870(cell motility);GO:0035035(histone acetyltransferase binding);GO:1990837(sequence-specific double-stranded DNA binding);GO:0001666(response to hypoxia);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0007565(female pregnancy);GO:0008284(positive regulation of cell proliferation);GO:0009611(response to wounding);GO:0009612(response to mechanical stimulus);GO:0010715(regulation of extracellular matrix disassembly);GO:0021854(hypothalamus development);GO:0021983(pituitary gland development);GO:0030335(positive regulation of cell migration);GO:0030578(PML body organization);GO:0032355(response to estradiol);GO:0034616(response to laminar fluid shear stress);GO:0044849(estrous cycle);GO:0045648(positive regulation of erythrocyte differentiation);GO:0045766(positive regulation of angiogenesis);GO:0050728(negative regulation of inflammatory response);GO:0051272(positive regulation of cellular component movement);GO:0060055(angiogenesis involved in wound healing);GO:0061614(pri-miRNA transcription from RNA polymerase II promoter);GO:0070301(cellular response to hydrogen peroxide);GO:0070555(response to interleukin-1);GO:0005667(transcription factor complex)","04014(Ras signaling pathway);04218(Cellular senescence);05200(Pathways in cancer);05211(Renal cell carcinoma);05166(HTLV-I infection)","K02678","NA","ETS proto-oncogene 1, transcription factor [Source:HGNC Symbol;Acc:HGNC:3488]",{"v":9.194866,"d":"9.19"},{"v":0.23056,"d":"0.23"},{"v":39.8805777238029,"d":"39.88"},{"v":5.31761440415277,"d":"5.32"},{"v":1.89760771894072e-11,"d":"0.00"},{"v":1.08684127673998e-08,"d":"0.00"},"up","yes"]
[192608,0,"chr9","-",111360693,111484745,"ENST00000259335",51,7391,"MSTRG.14899","KIAA0368","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005783(endoplasmic reticulum);GO:0032947(protein complex scaffold);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0000502(proteasome complex);GO:0031410(cytoplasmic vesicle);GO:0005813(centrosome);GO:0005815(microtubule organizing center);GO:0043248(proteasome assembly);GO:0005768(endosome);GO:0003674(molecular_function);GO:0005769(early endosome);GO:0005770(late endosome);GO:0030433(ubiquitin-dependent ERAD pathway);GO:0005793(endoplasmic reticulum-Golgi intermediate compartment);GO:0030139(endocytic vesicle);GO:0030134(ER to Golgi transport vesicle);GO:0005771(multivesicular body)","NA","NA","NA","KIAA0368 [Source:HGNC Symbol;Acc:HGNC:29020]",{"v":3.604605,"d":"3.60"},{"v":0.090035,"d":"0.09"},{"v":40.0355972677292,"d":"40.04"},{"v":5.32321142397496,"d":"5.32"},{"v":1.90502026672171e-11,"d":"0.00"},{"v":1.08684127673998e-08,"d":"0.00"},"up","yes"]
[28472,"j","chr11","-",45932712,46121174,"MSTRG.2354.3",18,3666,"MSTRG.2354","PHF21A","NA","NA","NA","NA","NA",{"v":9.339764,"d":"9.34"},{"v":0.239693,"d":"0.24"},{"v":38.9655267362835,"d":"38.97"},{"v":5.28412641372297,"d":"5.28"},{"v":2.18579195808197e-11,"d":"0.00"},{"v":1.21238593941613e-08,"d":"0.00"},"up","yes"]
[85239,0,"chr17","-",49289208,49361993,"ENST00000508237",8,4543,"MSTRG.6994","ZNF652","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0005515(protein binding)","NA","NA","NA","zinc finger protein 652 [Source:HGNC Symbol;Acc:HGNC:29147]",{"v":6.37277,"d":"6.37"},{"v":0.16412,"d":"0.16"},{"v":38.829941506215,"d":"38.83"},{"v":5.27909762884616,"d":"5.28"},{"v":2.50508800768687E-11,"d":"0.00"},{"v":1.25574100924818E-8,"d":"0.00"},"up","yes"]
[26624,"j","chr11","-",10573178,10606229,"MSTRG.2251.4",10,4554,"MSTRG.2251","MRVI1","NA","NA","NA","NA","NA",{"v":0.138581,"d":"0.14"},{"v":5.906592,"d":"5.91"},{"v":0.0234620911686468,"d":"0.02"},{"v":-5.41352458373209,"d":"-5.41"},{"v":2.52983471624194e-11,"d":"0.00"},{"v":1.25574100924818E-8,"d":"0.00"},"down","yes"]
[45123,"j","chr12","-",91987977,92145897,"MSTRG.3600.6",5,4030,"MSTRG.3600","LINC01619","NA","NA","NA","NA","NA",{"v":31.726065,"d":"31.73"},{"v":0.880334,"d":"0.88"},{"v":36.0386682781762,"d":"36.04"},{"v":5.17147379571782,"d":"5.17"},{"v":2.54065573501347e-11,"d":"0.00"},{"v":1.25574100924818E-8,"d":"0.00"},"up","yes"]
[46290,0,"chr12","-",108622277,108633959,"ENST00000550948",2,2256,"MSTRG.3684","SELPLG","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0007155(cell adhesion);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0050900(leukocyte migration);GO:0046718(viral entry into host cell);GO:0016032(viral process);GO:0005887(integral component of plasma membrane);GO:0005102(receptor binding);GO:0001931(uropod);GO:0001618(virus receptor activity);GO:0050901(leukocyte tethering or rolling);GO:0044853(plasma membrane raft);GO:0050902(leukocyte adhesive activation);GO:0071354(cellular response to interleukin-6)","04514(Cell adhesion molecules (CAMs));05150(Staphylococcus aureus infection)","K06544","NA","selectin P ligand [Source:HGNC Symbol;Acc:HGNC:10722]",{"v":130.500595,"d":"130.50"},{"v":3.672791,"d":"3.67"},{"v":35.5317236945963,"d":"35.53"},{"v":5.15103577244833,"d":"5.15"},{"v":2.57232230599954e-11,"d":"0.00"},{"v":1.25574100924818E-8,"d":"0.00"},"up","yes"]
[19386,0,"chr10","-",29458059,29634972,"ENST00000355867",38,7586,"MSTRG.1639","SVIL","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005829(cytosol);GO:0003779(actin binding);GO:0051015(actin filament binding);GO:0005886(plasma membrane);GO:0015629(actin cytoskeleton);GO:0005856(cytoskeleton);GO:0042995(cell projection);GO:0005515(protein binding);GO:0030054(cell junction);GO:0005925(focal adhesion);GO:0030496(midbody);GO:0007010(cytoskeleton organization);GO:0002102(podosome);GO:0032154(cleavage furrow);GO:0071437(invadopodium);GO:0032467(positive regulation of cytokinesis);GO:0043034(costamere);GO:0007519(skeletal muscle tissue development);GO:0036449(microtubule minus-end)","NA","NA","NA","supervillin [Source:HGNC Symbol;Acc:HGNC:11480]",{"v":4.493176,"d":"4.49"},{"v":0.118576,"d":"0.12"},{"v":37.8927944946701,"d":"37.89"},{"v":5.24385163365028,"d":"5.24"},{"v":2.57839450015902E-11,"d":"0.00"},{"v":1.25574100924818E-8,"d":"0.00"},"up","yes"]
[73878,0,"chr16","-",58520706,58629832,"ENST00000567188",50,7830,"MSTRG.5984","CNOT1","GO:0035195(gene silencing by miRNA);GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005829(cytosol);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0005515(protein binding);GO:0007275(multicellular organism development);GO:0005615(extracellular space);GO:0031047(gene silencing by RNA);GO:0010606(positive regulation of cytoplasmic mRNA processing body assembly);GO:0000932(P-body);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0006977(DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest);GO:0004535(poly(A)-specific ribonuclease activity);GO:0019904(protein domain specific binding);GO:0030331(estrogen receptor binding);GO:0032947(protein complex scaffold);GO:0042974(retinoic acid receptor binding);GO:0070016(armadillo repeat domain binding);GO:0000289(nuclear-transcribed mRNA poly(A) tail shortening);GO:0006417(regulation of translation);GO:0017148(negative regulation of translation);GO:0033147(negative regulation of intracellular estrogen receptor signaling pathway);GO:0048387(negative regulation of retinoic acid receptor signaling pathway);GO:0060213(positive regulation of nuclear-transcribed mRNA poly(A) tail shortening);GO:0061014(positive regulation of mRNA catabolic process);GO:0090503(RNA phosphodiester bond hydrolysis, exonucleolytic);GO:1900153(positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay);GO:2000036(regulation of stem cell population maintenance);GO:0030014(CCR4-NOT complex);GO:0030015(CCR4-NOT core complex)","03018(RNA degradation)","K12604","NA","CCR4-NOT transcription complex subunit 1 [Source:HGNC Symbol;Acc:HGNC:7877]",{"v":0.118142,"d":"0.12"},{"v":4.798171,"d":"4.80"},{"v":0.0246222987884342,"d":"0.02"},{"v":-5.3438907286894,"d":"-5.34"},{"v":2.68892339650892e-11,"d":"0.00"},{"v":1.26287786613856E-8,"d":"0.00"},"down","yes"]
[185749,0,"chr8","+",95133804,95156684,"ENST00000315367",2,2881,"MSTRG.14454","PLEKHF2","GO:0006810(transport);GO:0016020(membrane);GO:0015031(protein transport);GO:0046872(metal ion binding);GO:0005783(endoplasmic reticulum);GO:0005515(protein binding);GO:0005768(endosome);GO:0031901(early endosome membrane);GO:0030133(transport vesicle)","NA","NA","NA","pleckstrin homology and FYVE domain containing 2 [Source:HGNC Symbol;Acc:HGNC:20757]",{"v":0.256445,"d":"0.26"},{"v":10.675544,"d":"10.68"},{"v":0.0240217266679806,"d":"0.02"},{"v":-5.37951633490924,"d":"-5.38"},{"v":2.71953867407643e-11,"d":"0.00"},{"v":1.26287786613856E-8,"d":"0.00"},"down","yes"]
[193133,0,"chr9","+",122371080,122395703,"ENST00000362012",11,4964,"MSTRG.14948","PTGS1","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005794(Golgi apparatus);GO:0043231(intracellular membrane-bounded organelle);GO:0046872(metal ion binding);GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0006629(lipid metabolic process);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0006631(fatty acid metabolic process);GO:0006633(fatty acid biosynthetic process);GO:0006954(inflammatory response);GO:0051213(dioxygenase activity);GO:0020037(heme binding);GO:0008217(regulation of blood pressure);GO:0098869(cellular oxidant detoxification);GO:0004601(peroxidase activity);GO:0006979(response to oxidative stress);GO:0004666(prostaglandin-endoperoxide synthase activity);GO:0001516(prostaglandin biosynthetic process);GO:0019371(cyclooxygenase pathway);GO:0070062(extracellular exosome);GO:0006805(xenobiotic metabolic process);GO:0031090(organelle membrane);GO:0006693(prostaglandin metabolic process);GO:0042127(regulation of cell proliferation);GO:0001750(photoreceptor outer segment)","00590(Arachidonic acid metabolism);04611(Platelet activation);04923(Regulation of lipolysis in adipocyte);04726(Serotonergic synapse)","K00509","EC:1.14.99.1","prostaglandin-endoperoxide synthase 1 [Source:HGNC Symbol;Acc:HGNC:9604]",{"v":0.148836,"d":"0.15"},{"v":6.033409,"d":"6.03"},{"v":0.0246686408960506,"d":"0.02"},{"v":-5.34117795636371,"d":"-5.34"},{"v":3.49531794873391e-11,"d":"0.00"},{"v":1.55544820785125e-08,"d":"0.00"},"down","yes"]
[34836,0,"chr11","+",108222832,108369099,"ENST00000278616",63,13147,"MSTRG.2836","ATM","GO:0004674(protein serine/threonine kinase activity);GO:0006468(protein phosphorylation);GO:0005634(nucleus);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0006974(cellular response to DNA damage stimulus);GO:0007049(cell cycle);GO:0031410(cytoplasmic vesicle);GO:0036092(phosphatidylinositol-3-phosphate biosynthetic process);GO:0005730(nucleolus);GO:0006977(DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest);GO:0005654(nucleoplasm);GO:0000784(nuclear chromosome, telomeric region);GO:0043065(positive regulation of apoptotic process);GO:0047485(protein N-terminus binding);GO:0007165(signal transduction);GO:0042981(regulation of apoptotic process);GO:1901796(regulation of signal transduction by p53 class mediator);GO:0006260(DNA replication);GO:0016303(1-phosphatidylinositol-3-kinase activity);GO:0046777(protein autophosphorylation);GO:0032212(positive regulation of telomere maintenance via telomerase);GO:0090399(replicative senescence);GO:0000781(chromosome, telomeric region);GO:0006975(DNA damage induced protein phosphorylation);GO:0071044(histone mRNA catabolic process);GO:0018105(peptidyl-serine phosphorylation);GO:0000731(DNA synthesis involved in DNA repair);GO:0000732(strand displacement);GO:0007131(reciprocal meiotic recombination);GO:1900034(regulation of cellular response to heat);GO:0007094(mitotic spindle assembly checkpoint);GO:1990391(DNA repair complex);GO:0006281(DNA repair);GO:0000729(DNA double-strand break processing);GO:0006303(double-strand break repair via nonhomologous end joining);GO:1904354(negative regulation of telomere capping);GO:0030889(negative regulation of B cell proliferation);GO:0010212(response to ionizing radiation);GO:0032210(regulation of telomere maintenance via telomerase);GO:0007050(cell cycle arrest);GO:0071480(cellular response to gamma radiation);GO:0010506(regulation of autophagy);GO:0002331(pre-B cell allelic exclusion);GO:1904358(positive regulation of telomere maintenance via telomere lengthening);GO:0043517(positive regulation of DNA damage response, signal transduction by p53 class mediator);GO:0032403(protein complex binding);GO:0004677(DNA-dependent protein kinase activity);GO:0046983(protein dimerization activity);GO:0036289(peptidyl-serine autophosphorylation);GO:0071481(cellular response to X-ray);GO:0071500(cellular response to nitrosative stress);GO:0072434(signal transduction involved in mitotic G2 DNA damage checkpoint);GO:0097694(establishment of RNA localization to telomere);GO:0097695(establishment of macromolecular complex localization to telomere);GO:1904262(negative regulation of TORC1 signaling);GO:1904884(positive regulation of telomerase catalytic core complex assembly);GO:0004672(protein kinase activity);GO:0000077(DNA damage checkpoint);GO:0000724(double-strand break repair via homologous recombination);GO:0001541(ovarian follicle development);GO:0001666(response to hypoxia);GO:0001756(somitogenesis);GO:0002376(immune system process);GO:0002377(immunoglobulin production);GO:0006915(apoptotic process);GO:0007140(male meiotic nuclear division);GO:0007143(female meiotic nuclear division);GO:0007292(female gamete generation);GO:0007420(brain development);GO:0007507(heart development);GO:0008340(determination of adult lifespan);GO:0008585(female gonad development);GO:0008630(intrinsic apoptotic signaling pathway in response to DNA damage);GO:0009791(post-embryonic development);GO:0033129(positive regulation of histone phosphorylation);GO:0033151(V(D)J recombination);GO:0035264(multicellular organism growth);GO:0042159(lipoprotein catabolic process);GO:0043525(positive regulation of neuron apoptotic process);GO:0045141(meiotic telomere clustering);GO:0048538(thymus development);GO:0048599(oocyte development);GO:0051402(neuron apoptotic process);GO:0051726(regulation of cell cycle);GO:0070192(chromosome organization involved in meiotic cell cycle);GO:1901216(positive regulation of neuron death);GO:1903626(positive regulation of DNA catabolic process);GO:1903978(regulation of microglial cell activation);GO:1905843(regulation of cellular response to gamma radiation);GO:2001022(positive regulation of response to DNA damage stimulus);GO:0005737(cytoplasm);GO:0005819(spindle)","03440(Homologous recombination);04064(NF-kappa B signaling pathway);04068(FoxO signaling pathway);04110(Cell cycle);04210(Apoptosis);04115(p53 signaling pathway);04218(Cellular senescence);05202(Transcriptional misregulation in cancers);05206(MicroRNAs in cancer);05166(HTLV-I infection);05165(Human papillomavirus infection);01524(Platinum drug resistance)","K04728","EC:2.7.11.1","ATM serine/threonine kinase [Source:HGNC Symbol;Acc:HGNC:795]",{"v":0.107753,"d":"0.11"},{"v":4.179821,"d":"4.18"},{"v":0.0257793336126116,"d":"0.03"},{"v":-5.27764121879069,"d":"-5.28"},{"v":3.50536705495323e-11,"d":"0.00"},{"v":1.55544820785125e-08,"d":"0.00"},"down","yes"]
[41687,0,"chr12","+",51238908,51243784,"ENST00000552459",2,3664,"MSTRG.3374","DAZAP2","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016607(nuclear speck);GO:0005515(protein binding);GO:0042802(identical protein binding);GO:0050699(WW domain binding)","NA","NA","NA","DAZ associated protein 2 [Source:HGNC Symbol;Acc:HGNC:2684]",{"v":0.38561,"d":"0.39"},{"v":14.687038,"d":"14.69"},{"v":0.0262551237356368,"d":"0.03"},{"v":-5.25125719493245,"d":"-5.25"},{"v":3.96104916461578e-11,"d":"0.00"},{"v":1.71143288152186E-8,"d":"0.00"},"down","yes"]
[132565,"j","chr22","-",50523554,50532497,"MSTRG.10610.1",17,3950,"MSTRG.10610","TYMP","NA","NA","NA","NA","NA",{"v":0.836634,"d":"0.84"},{"v":31.212643,"d":"31.21"},{"v":0.0268043305400315,"d":"0.03"},{"v":-5.22139008670691,"d":"-5.22"},{"v":4.02831257169108e-11,"d":"0.00"},{"v":1.71143288152186E-8,"d":"0.00"},"down","yes"]
[57059,0,"chr14","+",76151936,76214343,"ENST00000261530",10,14007,"ENSG00000089916","GPATCH2L","GO:0005515(protein binding)","NA","NA","NA","G-patch domain containing 2 like [Source:HGNC Symbol;Acc:HGNC:20210]",{"v":0.049853,"d":"0.05"},{"v":1.997129,"d":"2.00"},{"v":0.0249623334296382,"d":"0.02"},{"v":-5.32410338898727,"d":"-5.32"},{"v":4.35797852634643E-11,"d":"0.00"},{"v":1.81291906696012e-08,"d":"0.00"},"down","yes"]
[165228,"j","chr6","-",33291654,33314387,"MSTRG.12950.1",24,7209,"MSTRG.12950","RGL2","NA","NA","NA","NA","NA",{"v":0.448626,"d":"0.45"},{"v":16.300724,"d":"16.30"},{"v":0.0275218450419748,"d":"0.03"},{"v":-5.18327899939744,"d":"-5.18"},{"v":5.02355075410432e-11,"d":"0.00"},{"v":2.04714819301949E-8,"d":"0.00"},"down","yes"]
[144797,0,"chr3","-",197671393,197749699,"ENST00000273582",21,6955,"MSTRG.11473","RUBCN","GO:0043231(intracellular membrane-bounded organelle);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0005515(protein binding);GO:0006914(autophagy);GO:0002376(immune system process);GO:0005764(lysosome);GO:0005768(endosome);GO:0006897(endocytosis);GO:0005769(early endosome);GO:0005770(late endosome);GO:0006909(phagocytosis);GO:0010507(negative regulation of autophagy);GO:1901097(negative regulation of autophagosome maturation);GO:0043553(negative regulation of phosphatidylinositol 3-kinase activity);GO:0045806(negative regulation of endocytosis);GO:0071985(multivesicular body sorting pathway)","04140(Autophagy - animal)","K19330","NA","RUN and cysteine rich domain containing beclin 1 interacting protein [Source:HGNC Symbol;Acc:HGNC:28991]",{"v":4.125762,"d":"4.13"},{"v":0.117719,"d":"0.12"},{"v":35.047545425972,"d":"35.05"},{"v":5.13124150272441,"d":"5.13"},{"v":5.42095770333773e-11,"d":"0.00"},{"v":2.16491366840496e-08,"d":"0.00"},"up","yes"]
[169274,0,"chr6","-",132743870,132758008,"ENST00000326499",7,2118,"MSTRG.13286","VNN2","GO:0016810(hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds);GO:0006807(nitrogen compound metabolic process);GO:0016811(hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides);GO:0016020(membrane);GO:0016787(hydrolase activity);GO:0005886(plasma membrane);GO:0031225(anchored component of membrane);GO:0005576(extracellular region);GO:0006501(C-terminal protein lipidation);GO:0006928(movement of cell or subcellular component);GO:0017159(pantetheine hydrolase activity);GO:0015939(pantothenate metabolic process)","00770(Pantothenate and CoA biosynthesis)","K08069","EC:3.5.1.92","vanin 2 [Source:HGNC Symbol;Acc:HGNC:12706]",{"v":2.930537,"d":"2.93"},{"v":103.098045,"d":"103.10"},{"v":0.0284247581998281,"d":"0.03"},{"v":-5.13670811314243,"d":"-5.14"},{"v":6.2562963429393e-11,"d":"0.00"},{"v":2.4495240269767e-08,"d":"0.00"},"down","yes"]
[65691,0,"chr15","-",82536755,82540457,"ENST00000560229",4,776,"MSTRG.5381","RPS17","GO:0003723(RNA binding);GO:0016020(membrane);GO:0006412(translation);GO:0006413(translational initiation);GO:0030529(intracellular ribonucleoprotein complex);GO:0005622(intracellular);GO:0003735(structural constituent of ribosome);GO:0005840(ribosome);GO:0022627(cytosolic small ribosomal subunit);GO:0005925(focal adhesion);GO:0006364(rRNA processing);GO:0042274(ribosomal small subunit biogenesis);GO:0000028(ribosomal small subunit assembly);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0031012(extracellular matrix);GO:0000184(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay);GO:0019083(viral transcription);GO:0006614(SRP-dependent cotranslational protein targeting to membrane);GO:0034101(erythrocyte homeostasis)","03010(Ribosome)","K02962","NA","ribosomal protein S17 [Source:HGNC Symbol;Acc:HGNC:10397]",{"v":161.5224,"d":"161.52"},{"v":4.983591,"d":"4.98"},{"v":32.410845914121,"d":"32.41"},{"v":5.01840476997635,"d":"5.02"},{"v":6.87435703951592e-11,"d":"0.00"},{"v":2.63975310317411e-08,"d":"0.00"},"up","yes"]
[163917,0,"chr6","+",29942245,29945884,"ENST00000376806",8,1854,"MSTRG.12803","HLA-A","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005794(Golgi apparatus);GO:0005783(endoplasmic reticulum);GO:0006955(immune response);GO:0002376(immune system process);GO:0050776(regulation of immune response);GO:0005886(plasma membrane);GO:0005887(integral component of plasma membrane);GO:0019882(antigen processing and presentation);GO:0002474(antigen processing and presentation of peptide antigen via MHC class I);GO:0042612(MHC class I protein complex);GO:0016567(protein ubiquitination);GO:0005789(endoplasmic reticulum membrane);GO:0070062(extracellular exosome);GO:0002479(antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent);GO:0016032(viral process);GO:0030670(phagocytic vesicle membrane);GO:0009986(cell surface);GO:0000139(Golgi membrane);GO:0060333(interferon-gamma-mediated signaling pathway);GO:0012507(ER to Golgi transport vesicle membrane);GO:0060337(type I interferon signaling pathway);GO:0042605(peptide antigen binding);GO:0071556(integral component of lumenal side of endoplasmic reticulum membrane);GO:0031901(early endosome membrane);GO:0002480(antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent);GO:0042270(protection from natural killer cell mediated cytotoxicity);GO:0055038(recycling endosome membrane);GO:0030881(beta-2-microglobulin binding);GO:0046977(TAP binding)","04514(Cell adhesion molecules (CAMs));04144(Endocytosis);04145(Phagosome);04218(Cellular senescence);04650(Natural killer cell mediated cytotoxicity);04612(Antigen processing and presentation);05203(Viral carcinogenesis);05320(Autoimmune thyroid disease);05330(Allograft rejection);05332(Graft-versus-host disease);05416(Viral myocarditis);04940(Type I diabetes mellitus);05166(HTLV-I infection);05168(Herpes simplex infection);05167(Kaposi's sarcoma-associated herpesvirus infection);05169(Epstein-Barr virus infection);05165(Human papillomavirus infection)","NA","NA","major histocompatibility complex, class I, A [Source:HGNC Symbol;Acc:HGNC:4931]",{"v":1.736811,"d":"1.74"},{"v":60.84761,"d":"60.85"},{"v":0.0285436190509372,"d":"0.03"},{"v":-5.13068792378276,"d":"-5.13"},{"v":7.14222682100685e-11,"d":"0.00"},{"v":2.69086764456348e-08,"d":"0.00"},"down","yes"]
[85657,"j","chr17","+",50719570,50750996,"MSTRG.7029.3",13,2179,"MSTRG.7029","LUC7L3","NA","NA","NA","NA","NA",{"v":10.5878,"d":"10.59"},{"v":0.308321,"d":"0.31"},{"v":34.3401844181875,"d":"34.34"},{"v":5.1018258819994,"d":"5.10"},{"v":7.45509729677028e-11,"d":"0.00"},{"v":2.75672931151683e-08,"d":"0.00"},"up","yes"]
[125876,0,"chr21","-",8393419,8394341,"ENST00000625598",1,923,"MSTRG.9941","FP236383.2","NA","NA","NA","NA","NA",{"v":31.023783,"d":"31.02"},{"v":0.929504,"d":"0.93"},{"v":33.3767073622061,"d":"33.38"},{"v":5.06076973363467,"d":"5.06"},{"v":9.26190501024291e-11,"d":"0.00"},{"v":3.34612587221003E-8,"d":"0.00"},"up","yes"]
[54321,0,"chr14","-",35401545,35404140,"ENST00000557389",5,1537,"MSTRG.4322","NFKBIA","GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0038095(Fc-epsilon receptor signaling pathway);GO:0042802(identical protein binding);GO:0002223(stimulatory C-type lectin receptor signaling pathway);GO:0016579(protein deubiquitination);GO:0050852(T cell receptor signaling pathway);GO:0016032(viral process);GO:0031625(ubiquitin protein ligase binding);GO:0008134(transcription factor binding);GO:0019899(enzyme binding);GO:0006915(apoptotic process);GO:0042994(cytoplasmic sequestering of transcription factor);GO:0043066(negative regulation of apoptotic process);GO:0051092(positive regulation of NF-kappaB transcription factor activity);GO:0007249(I-kappaB kinase/NF-kappaB signaling);GO:0051059(NF-kappaB binding);GO:0032270(positive regulation of cellular protein metabolic process);GO:0010745(negative regulation of macrophage derived foam cell differentiation);GO:0010875(positive regulation of cholesterol efflux);GO:0010888(negative regulation of lipid storage);GO:0005622(intracellular);GO:0043392(negative regulation of DNA binding);GO:0033256(I-kappaB/NF-kappaB complex);GO:0042345(regulation of NF-kappaB import into nucleus);GO:0008139(nuclear localization sequence binding);GO:0031072(heat shock protein binding);GO:0032403(protein complex binding);GO:0000060(protein import into nucleus, translocation);GO:0007253(cytoplasmic sequestering of NF-kappaB);GO:0010468(regulation of gene expression);GO:0031663(lipopolysaccharide-mediated signaling pathway);GO:0032088(negative regulation of NF-kappaB transcription factor activity);GO:0032495(response to muramyl dipeptide);GO:0032496(response to lipopolysaccharide);GO:0033209(tumor necrosis factor-mediated signaling pathway);GO:0034142(toll-like receptor 4 signaling pathway);GO:0035994(response to muscle stretch);GO:0042127(regulation of cell proliferation);GO:0043330(response to exogenous dsRNA);GO:0045638(negative regulation of myeloid cell differentiation);GO:0045746(negative regulation of Notch signaling pathway);GO:0045893(positive regulation of transcription, DNA-templated);GO:0050729(positive regulation of inflammatory response);GO:0070417(cellular response to cold);GO:0070427(nucleotide-binding oligomerization domain containing 1 signaling pathway);GO:0070431(nucleotide-binding oligomerization domain containing 2 signaling pathway);GO:0071345(cellular response to cytokine stimulus);GO:0071407(cellular response to organic cyclic compound);GO:0097421(liver regeneration);GO:0043234(protein complex)","04064(NF-kappa B signaling pathway);04668(TNF signaling pathway);04024(cAMP signaling pathway);04210(Apoptosis);04620(Toll-like receptor signaling pathway);04621(NOD-like receptor signaling pathway);04622(RIG-I-like receptor signaling pathway);04623(Cytosolic DNA-sensing pathway);04660(T cell receptor signaling pathway);04658(Th1 and Th2 cell differentiation);04659(Th17 cell differentiation);04657(IL-17 signaling pathway);04662(B cell receptor signaling pathway);04062(Chemokine signaling pathway);04920(Adipocytokine signaling pathway);04926(Relaxin signaling pathway);04722(Neurotrophin signaling pathway);04380(Osteoclast differentiation);05200(Pathways in cancer);05203(Viral carcinogenesis);05220(Chronic myeloid leukemia);05215(Prostate cancer);05222(Small cell lung cancer);04931(Insulin resistance);05120(Epithelial cell signaling in Helicobacter pylori infection);05131(Shigellosis);05134(Legionellosis);05166(HTLV-I infection);05162(Measles);05164(Influenza A);05161(Hepatitis B);05160(Hepatitis C);05168(Herpes simplex infection);05167(Kaposi's sarcoma-associated herpesvirus infection);05169(Epstein-Barr virus infection);05145(Toxoplasmosis);05140(Leishmaniasis);05142(Chagas disease (American trypanosomiasis))","NA","NA","NFKB inhibitor alpha [Source:HGNC Symbol;Acc:HGNC:7797]",{"v":0.669067,"d":"0.67"},{"v":23.990564,"d":"23.99"},{"v":0.027888756596135,"d":"0.03"},{"v":-5.16417257568739,"d":"-5.16"},{"v":9.38416710956339e-11,"d":"0.00"},{"v":3.34612587221003E-8,"d":"0.00"},"down","yes"]
[189351,"j","chr9","-",21003870,21031680,"MSTRG.14703.2",9,4109,"MSTRG.14703","HACD4","NA","NA","NA","NA","NA",{"v":0.325977,"d":"0.33"},{"v":11.31849,"d":"11.32"},{"v":0.0288003965193237,"d":"0.03"},{"v":-5.11776751517228,"d":"-5.12"},{"v":1.06888651090873E-10,"d":"0.00"},{"v":3.74447821926762e-08,"d":"0.00"},"down","yes"]
[43178,0,"chr12","-",56663343,56688408,"ENST00000614328",9,2077,"MSTRG.3466","PTGES3","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016853(isomerase activity);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0006629(lipid metabolic process);GO:0006631(fatty acid metabolic process);GO:0006633(fatty acid biosynthetic process);GO:0005515(protein binding);GO:0000781(chromosome, telomeric region);GO:0070062(extracellular exosome);GO:0006805(xenobiotic metabolic process);GO:0000723(telomere maintenance);GO:0007165(signal transduction);GO:0043234(protein complex);GO:0051879(Hsp90 protein binding);GO:0042327(positive regulation of phosphorylation);GO:0051082(unfolded protein binding);GO:0050220(prostaglandin-E synthase activity);GO:0001516(prostaglandin biosynthetic process);GO:0006693(prostaglandin metabolic process);GO:0019371(cyclooxygenase pathway);GO:0051973(positive regulation of telomerase activity);GO:0003720(telomerase activity);GO:0007004(telomere maintenance via telomerase);GO:0005697(telomerase holoenzyme complex);GO:1900034(regulation of cellular response to heat);GO:0050821(protein stabilization);GO:0070182(DNA polymerase binding);GO:1905323(telomerase holoenzyme complex assembly);GO:0051131(chaperone-mediated protein complex assembly);GO:0070389(chaperone cofactor-dependent protein refolding);GO:0005978(glycogen biosynthetic process);GO:0008283(cell proliferation);GO:0042921(glucocorticoid receptor signaling pathway);GO:0043588(skin development);GO:0060430(lung saccule development)","00590(Arachidonic acid metabolism)","K15730","EC:5.3.99.3","prostaglandin E synthase 3 [Source:HGNC Symbol;Acc:HGNC:16049]",{"v":0.425725,"d":"0.43"},{"v":14.688112,"d":"14.69"},{"v":0.0289843241936064,"d":"0.03"},{"v":-5.10858334204048,"d":"-5.11"},{"v":1.35758931341181E-10,"d":"0.00"},{"v":4.67385231210466e-08,"d":"0.00"},"down","yes"]
[113258,0,"chr2","+",108448561,108509398,"ENST00000309863",23,7537,"MSTRG.9032","GCC2","GO:0006810(transport);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0015031(protein transport);GO:0005794(Golgi apparatus);GO:0005654(nucleoplasm);GO:0005515(protein binding);GO:0042802(identical protein binding);GO:0000042(protein targeting to Golgi);GO:0005829(cytosol);GO:0005802(trans-Golgi network);GO:0042147(retrograde transport, endosome to Golgi);GO:0090161(Golgi ribbon formation);GO:0006622(protein targeting to lysosome);GO:0034499(late endosome to Golgi transport);GO:0031023(microtubule organizing center organization);GO:0034453(microtubule anchoring);GO:0034067(protein localization to Golgi apparatus);GO:0070861(regulation of protein exit from endoplasmic reticulum);GO:0071955(recycling endosome to Golgi transport)","NA","NA","NA","GRIP and coiled-coil domain containing 2 [Source:HGNC Symbol;Acc:HGNC:23218]",{"v":0.129478,"d":"0.13"},{"v":4.352032,"d":"4.35"},{"v":0.0297511599179418,"d":"0.03"},{"v":-5.07091027344688,"d":"-5.07"},{"v":1.68277821321309e-10,"d":"0.00"},{"v":5.69520599346423e-08,"d":"0.00"},"down","yes"]
[107805,"j","chr2","+",24554453,24770702,"MSTRG.8537.5",25,7251,"MSTRG.8537","NCOA1","NA","NA","NA","NA","NA",{"v":9.118008,"d":"9.12"},{"v":0.310108,"d":"0.31"},{"v":29.4026855160138,"d":"29.40"},{"v":4.87787602558489,"d":"4.88"},{"v":1.96846783001306E-10,"d":"0.00"},{"v":6.55106093828347e-08,"d":"0.00"},"up","yes"]
[90238,"j","chr18","+",2655750,2803588,"MSTRG.7380.2",47,7235,"MSTRG.7380","SMCHD1","NA","NA","NA","NA","NA",{"v":1.271396,"d":"1.27"},{"v":39.105007,"d":"39.11"},{"v":0.0325123583279246,"d":"0.03"},{"v":-4.94286798211306,"d":"-4.94"},{"v":2.1409616466651e-10,"d":"0.00"},{"v":7.00831510829652e-08,"d":"0.00"},"down","yes"]
[79793,"j","chr17","-",16029010,16215539,"MSTRG.6470.1",47,11027,"MSTRG.6470","NCOR1","NA","NA","NA","NA","NA",{"v":7.480408,"d":"7.48"},{"v":0.260734,"d":"0.26"},{"v":28.6898064694286,"d":"28.69"},{"v":4.84246633115228,"d":"4.84"},{"v":2.25198529184682e-10,"d":"0.00"},{"v":7.20274076434431e-08,"d":"0.00"},"up","yes"]
[170566,0,"chr6","-",159682139,159693241,"ENST00000444946",4,917,"MSTRG.13403","SOD2","GO:0046872(metal ion binding);GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0004784(superoxide dismutase activity);GO:0006801(superoxide metabolic process);GO:0003677(DNA binding);GO:0019825(oxygen binding);GO:0019899(enzyme binding);GO:0030145(manganese ion binding);GO:0042802(identical protein binding);GO:0000302(response to reactive oxygen species);GO:0000303(response to superoxide);GO:0001306(age-dependent response to oxidative stress);GO:0001666(response to hypoxia);GO:0001836(release of cytochrome c from mitochondria);GO:0001889(liver development);GO:0003032(detection of oxygen);GO:0003069(acetylcholine-mediated vasodilation involved in regulation of systemic arterial blood pressure);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0006749(glutathione metabolic process);GO:0006979(response to oxidative stress);GO:0007005(mitochondrion organization);GO:0007507(heart development);GO:0007568(aging);GO:0007626(locomotory behavior);GO:0008217(regulation of blood pressure);GO:0008630(intrinsic apoptotic signaling pathway in response to DNA damage);GO:0008631(intrinsic apoptotic signaling pathway in response to oxidative stress);GO:0008637(apoptotic mitochondrial changes);GO:0009314(response to radiation);GO:0009409(response to cold);GO:0009791(post-embryonic development);GO:0010042(response to manganese ion);GO:0010043(response to zinc ion);GO:0010269(response to selenium ion);GO:0010332(response to gamma radiation);GO:0014823(response to activity);GO:0019430(removal of superoxide radicals);GO:0022904(respiratory electron transport chain);GO:0030097(hemopoiesis);GO:0031667(response to nutrient levels);GO:0032496(response to lipopolysaccharide);GO:0033591(response to L-ascorbic acid);GO:0034021(response to silicon dioxide);GO:0035900(response to isolation stress);GO:0035902(response to immobilization stress);GO:0042311(vasodilation);GO:0042493(response to drug);GO:0042542(response to hydrogen peroxide);GO:0042554(superoxide anion generation);GO:0042743(hydrogen peroxide metabolic process);GO:0043066(negative regulation of apoptotic process);GO:0045429(positive regulation of nitric oxide biosynthetic process);GO:0045599(negative regulation of fat cell differentiation);GO:0046686(response to cadmium ion);GO:0048147(negative regulation of fibroblast proliferation);GO:0048666(neuron development);GO:0048678(response to axon injury);GO:0048773(erythrophore differentiation);GO:0050665(hydrogen peroxide biosynthetic process);GO:0050790(regulation of catalytic activity);GO:0051260(protein homooligomerization);GO:0051602(response to electrical stimulus);GO:0051881(regulation of mitochondrial membrane potential);GO:0055072(iron ion homeostasis);GO:0055093(response to hyperoxia);GO:0071000(response to magnetism);GO:0071361(cellular response to ethanol);GO:0005737(cytoplasm);GO:0005739(mitochondrion);GO:0005743(mitochondrial inner membrane);GO:0042645(mitochondrial nucleoid);GO:0043209(myelin sheath);GO:0008285(negative regulation of cell proliferation);GO:0030335(positive regulation of cell migration);GO:0005759(mitochondrial matrix);GO:0070062(extracellular exosome);GO:0035722(interleukin-12-mediated signaling pathway);GO:0051289(protein homotetramerization);GO:0034599(cellular response to oxidative stress);GO:0043524(negative regulation of neuron apoptotic process);GO:1902176(negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway);GO:0001315(age-dependent response to reactive oxygen species);GO:0032364(oxygen homeostasis)","04068(FoxO signaling pathway);04146(Peroxisome);04211(Longevity regulating pathway - mammal);04213(Longevity regulating pathway - multiple species);05016(Huntington's disease)","K04564","EC:1.15.1.1","superoxide dismutase 2 [Source:HGNC Symbol;Acc:HGNC:11180]",{"v":1.21344,"d":"1.21"},{"v":38.953186,"d":"38.95"},{"v":0.0311512388229297,"d":"0.03"},{"v":-5.00456665226673,"d":"-5.00"},{"v":2.272499339712e-10,"d":"0.00"},{"v":7.20274076434431e-08,"d":"0.00"},"down","yes"]
[164118,"j","chr6","-",30676389,30691484,"MSTRG.12827.1",7,5596,"MSTRG.12827","NRM","NA","NA","NA","NA","NA",{"v":11.746035,"d":"11.75"},{"v":0.409748,"d":"0.41"},{"v":28.6664852543515,"d":"28.67"},{"v":4.84129312409226,"d":"4.84"},{"v":2.41049973001093e-10,"d":"0.00"},{"v":7.52075915763409e-08,"d":"0.00"},"up","yes"]
[169279,0,"chr6","-",132744026,132757970,"ENST00000392389",7,1920,"MSTRG.13286","VNN2","GO:0016810(hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds);GO:0006807(nitrogen compound metabolic process);GO:0016811(hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides);GO:0016020(membrane);GO:0016787(hydrolase activity);GO:0005886(plasma membrane);GO:0031225(anchored component of membrane);GO:0005576(extracellular region);GO:0006501(C-terminal protein lipidation);GO:0006928(movement of cell or subcellular component);GO:0017159(pantetheine hydrolase activity);GO:0015939(pantothenate metabolic process)","00770(Pantothenate and CoA biosynthesis)","K08069","EC:3.5.1.92","vanin 2 [Source:HGNC Symbol;Acc:HGNC:12706]",{"v":0.530122,"d":"0.53"},{"v":17.036612,"d":"17.04"},{"v":0.031116632814083,"d":"0.03"},{"v":-5.00617023758852,"d":"-5.01"},{"v":2.6151382122587E-10,"d":"0.00"},{"v":8.03370458805873e-08,"d":"0.00"},"down","yes"]
[5796,"j","chr1","-",47183556,47211926,"MSTRG.535.1",6,1291,"MSTRG.535","PDZK1IP1","NA","NA","NA","NA","NA",{"v":17.837004,"d":"17.84"},{"v":0.6037,"d":"0.60"},{"v":29.5461388106675,"d":"29.55"},{"v":4.88489770134184,"d":"4.88"},{"v":2.87460415729996e-10,"d":"0.00"},{"v":8.69698421408571e-08,"d":"0.00"},"up","yes"]
[38829,"j","chr12","-",10372346,10409769,"MSTRG.3171.2",14,2851,"MSTRG.3171","KLRC4-KLRK1","NA","NA","NA","NA","NA",{"v":22.395685,"d":"22.40"},{"v":0.801111,"d":"0.80"},{"v":27.9557826568353,"d":"27.96"},{"v":4.80507483045833,"d":"4.81"},{"v":3.01578535900928E-10,"d":"0.00"},{"v":8.98794060428317e-08,"d":"0.00"},"up","yes"]
[101845,"j","chr19","-",41423896,41428730,"MSTRG.8181.1",4,2224,"MSTRG.8181","B3GNT8","NA","NA","NA","NA","NA",{"v":0.287282,"d":"0.29"},{"v":9.206927,"d":"9.21"},{"v":0.0312028106663602,"d":"0.03"},{"v":-5.00218020069409,"d":"-5.00"},{"v":3.30632401915065e-10,"d":"0.00"},{"v":9.70892323741179e-08,"d":"0.00"},"down","yes"]
[191958,0,"chr9","-",95443412,95506599,"ENST00000375290",21,10631,"ENSG00000185920","PTCH1","GO:0048471(perinuclear region of cytoplasm);GO:0043433(negative regulation of sequence-specific DNA binding transcription factor activity);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005515(protein binding);GO:0007224(smoothened signaling pathway);GO:0060037(pharyngeal system development);GO:0005886(plasma membrane);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0030666(endocytic vesicle membrane);GO:0009887(animal organ morphogenesis);GO:0009953(dorsal/ventral pattern formation);GO:0005901(caveola);GO:0005794(Golgi apparatus);GO:0045668(negative regulation of osteoblast differentiation);GO:0071397(cellular response to cholesterol);GO:0015485(cholesterol binding);GO:0040015(negative regulation of multicellular organism growth);GO:0010875(positive regulation of cholesterol efflux);GO:0072001(renal system development);GO:0007420(brain development);GO:0043231(intracellular membrane-bounded organelle);GO:0060170(ciliary membrane);GO:0008589(regulation of smoothened signaling pathway);GO:0016485(protein processing);GO:0045879(negative regulation of smoothened signaling pathway);GO:0061053(somite development);GO:0072661(protein targeting to plasma membrane);GO:0030326(embryonic limb morphogenesis);GO:0030332(cyclin binding);GO:0005113(patched binding);GO:0005119(smoothened binding);GO:0008158(hedgehog receptor activity);GO:0008201(heparin binding);GO:0032403(protein complex binding);GO:0097108(hedgehog family protein binding);GO:0001658(branching involved in ureteric bud morphogenesis);GO:0001701(in utero embryonic development);GO:0001709(cell fate determination);GO:0001841(neural tube formation);GO:0001843(neural tube closure);GO:0003007(heart morphogenesis);GO:0007165(signal transduction);GO:0007346(regulation of mitotic cell cycle);GO:0007389(pattern specification process);GO:0008285(negative regulation of cell proliferation);GO:0008544(epidermis development);GO:0009612(response to mechanical stimulus);GO:0009957(epidermal cell fate specification);GO:0010157(response to chlorate);GO:0014070(response to organic cyclic compound);GO:0021522(spinal cord motor neuron differentiation);GO:0021532(neural tube patterning);GO:0021904(dorsal/ventral neural tube patterning);GO:0021997(neural plate axis specification);GO:0030850(prostate gland development);GO:0030879(mammary gland development);GO:0032355(response to estradiol);GO:0032526(response to retinoic acid);GO:0032880(regulation of protein localization);GO:0035108(limb morphogenesis);GO:0035137(hindlimb morphogenesis);GO:0040008(regulation of growth);GO:0042127(regulation of cell proliferation);GO:0042493(response to drug);GO:0042593(glucose homeostasis);GO:0043616(keratinocyte proliferation);GO:0045606(positive regulation of epidermal cell differentiation);GO:0045892(negative regulation of transcription, DNA-templated);GO:0045893(positive regulation of transcription, DNA-templated);GO:0048568(embryonic organ development);GO:0050680(negative regulation of epithelial cell proliferation);GO:0051782(negative regulation of cell division);GO:0060603(mammary gland duct morphogenesis);GO:0060644(mammary gland epithelial cell differentiation);GO:0060831(smoothened signaling pathway involved in dorsal/ventral neural tube patterning);GO:0061005(cell differentiation involved in kidney development);GO:0071679(commissural neuron axon guidance);GO:0072203(cell proliferation involved in metanephros development);GO:0005634(nucleus);GO:0005929(cilium);GO:0014069(postsynaptic density);GO:0030496(midbody);GO:0044294(dendritic growth cone);GO:0044295(axonal growth cone)","04340(Hedgehog signaling pathway);04024(cAMP signaling pathway);04360(Axon guidance);05200(Pathways in cancer);05205(Proteoglycans in cancer);05217(Basal cell carcinoma)","NA","NA","patched 1 [Source:HGNC Symbol;Acc:HGNC:9585]",{"v":2.127087,"d":"2.13"},{"v":0.07364,"d":"0.07"},{"v":28.8849402498642,"d":"28.88"},{"v":4.85224560527204,"d":"4.85"},{"v":3.40839841526899e-10,"d":"0.00"},{"v":9.86360863131756e-08,"d":"0.00"},"up","yes"]
[199330,0,"chrX","-",109641337,109733403,"ENST00000348502",16,5032,"MSTRG.15400","ACSL4","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0003824(catalytic activity);GO:0006629(lipid metabolic process);GO:0008152(metabolic process);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0006631(fatty acid metabolic process);GO:0005739(mitochondrion);GO:0016874(ligase activity);GO:0005741(mitochondrial outer membrane);GO:0001676(long-chain fatty acid metabolic process);GO:0005777(peroxisome);GO:0005778(peroxisomal membrane);GO:0043231(intracellular membrane-bounded organelle);GO:0070062(extracellular exosome);GO:0035338(long-chain fatty-acyl-CoA biosynthetic process);GO:0031090(organelle membrane);GO:0005811(lipid particle);GO:0004467(long-chain fatty acid-CoA ligase activity);GO:0031957(very long-chain fatty acid-CoA ligase activity);GO:0102391(decanoate--CoA ligase activity);GO:0047676(arachidonate-CoA ligase activity);GO:0044233(ER-mitochondrion membrane contact site);GO:0006641(triglyceride metabolic process);GO:0007584(response to nutrient);GO:0015908(fatty acid transport);GO:0030182(neuron differentiation);GO:0060136(embryonic process involved in female pregnancy);GO:0060996(dendritic spine development);GO:0070672(response to interleukin-15);GO:0031966(mitochondrial membrane);GO:0043025(neuronal cell body)","00061(Fatty acid biosynthesis);00071(Fatty acid degradation);04146(Peroxisome);04216(Ferroptosis);04920(Adipocytokine signaling pathway);03320(PPAR signaling pathway)","K01897","EC:6.2.1.3","acyl-CoA synthetase long chain family member 4 [Source:HGNC Symbol;Acc:HGNC:3571]",{"v":0.342837,"d":"0.34"},{"v":10.267907,"d":"10.27"},{"v":0.0333891804824489,"d":"0.03"},{"v":-4.90447550602977,"d":"-4.90"},{"v":3.70804030770066e-10,"d":"0.00"},{"v":1.05774498377381E-7,"d":"0.00"},"down","yes"]
[1337,"j","chr1","+",9651672,9729182,"MSTRG.139.2",25,5702,"MSTRG.139","PIK3CD","NA","NA","NA","NA","NA",{"v":0.135584,"d":"0.14"},{"v":4.258825,"d":"4.26"},{"v":0.0318360111063498,"d":"0.03"},{"v":-4.97319660507388,"d":"-4.97"},{"v":3.77793927338094e-10,"d":"0.00"},{"v":1.06250551282916e-07,"d":"0.00"},"down","yes"]
[129159,"j","chr22","+",22409770,22901438,"MSTRG.10249.3",5,901,"MSTRG.10249","IGLL5","NA","NA","NA","NA","NA",{"v":24.906639,"d":"24.91"},{"v":0.88262,"d":"0.88"},{"v":28.2189832544017,"d":"28.22"},{"v":4.81859410265748,"d":"4.82"},{"v":4.18347731126814E-10,"d":"0.00"},{"v":1.16021770765836E-7,"d":"0.00"},"up","yes"]
[131131,0,"chr22","+",37849481,37888630,"ENST00000406934",11,2282,"MSTRG.10442","EIF3L","GO:0005737(cytoplasm);GO:0003743(translation initiation factor activity);GO:0001731(formation of translation preinitiation complex);GO:0006412(translation);GO:0006413(translational initiation);GO:0006446(regulation of translational initiation);GO:0005852(eukaryotic translation initiation factor 3 complex);GO:0016282(eukaryotic 43S preinitiation complex);GO:0033290(eukaryotic 48S preinitiation complex);GO:0003723(RNA binding);GO:0016020(membrane);GO:0005515(protein binding);GO:0005829(cytosol);GO:0075525(viral translational termination-reinitiation);GO:0001650(fibrillar center);GO:0005654(nucleoplasm);GO:0005730(nucleolus)","NA","NA","NA","eukaryotic translation initiation factor 3 subunit L [Source:HGNC Symbol;Acc:HGNC:18138]",{"v":23.413244,"d":"23.41"},{"v":0.87504,"d":"0.88"},{"v":26.7567699762297,"d":"26.76"},{"v":4.74183206211736,"d":"4.74"},{"v":4.78537560178688e-10,"d":"0.00"},{"v":1.3089641098148e-07,"d":"0.00"},"up","yes"]
[131589,0,"chr22","-",40410281,40636685,"ENST00000355630",15,4496,"MSTRG.10504","MKL1","GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0005737(cytoplasm);GO:0005634(nucleus);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0003713(transcription coactivator activity);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003779(actin binding);GO:0005515(protein binding);GO:0003785(actin monomer binding);GO:0010735(positive regulation of transcription via serum response element binding);GO:0001105(RNA polymerase II transcription coactivator activity);GO:0051145(smooth muscle cell differentiation);GO:0043522(leucine zipper domain binding);GO:0043086(negative regulation of catalytic activity);GO:0004864(protein phosphatase inhibitor activity);GO:0000976(transcription regulatory region sequence-specific DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0001764(neuron migration);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0030036(actin cytoskeleton organization);GO:0030900(forebrain development);GO:0031175(neuron projection development);GO:0043154(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process);GO:0045893(positive regulation of transcription, DNA-templated);GO:2001234(negative regulation of apoptotic signaling pathway)","NA","NA","NA","megakaryoblastic leukemia (translocation) 1 [Source:HGNC Symbol;Acc:HGNC:14334]",{"v":7.060628,"d":"7.06"},{"v":0.258774,"d":"0.26"},{"v":27.2849204325009,"d":"27.28"},{"v":4.77003193145833,"d":"4.77"},{"v":5.19502389329086e-10,"d":"0.00"},{"v":1.40181401488151e-07,"d":"0.00"},"up","yes"]
[124781,0,"chr20","+",56359109,56360712,"ENST00000437418",2,614,"MSTRG.9842","FAM210B","GO:0016020(membrane);GO:0016021(integral component of membrane)","NA","NA","NA","family with sequence similarity 210 member B [Source:HGNC Symbol;Acc:HGNC:16102]",{"v":71.902931,"d":"71.90"},{"v":2.756867,"d":"2.76"},{"v":26.0813927548917,"d":"26.08"},{"v":4.70494900689981,"d":"4.70"},{"v":6.26764015262633e-10,"d":"0.00"},{"v":1.66869651423523E-7,"d":"0.00"},"up","yes"]
[95125,0,"chr19","-",4536409,4540474,"ENST00000306390",2,3036,"MSTRG.7695","LRG1","GO:0016020(membrane);GO:0043231(intracellular membrane-bounded organelle);GO:0005576(extracellular region);GO:0005615(extracellular space);GO:0003674(molecular_function);GO:0008150(biological_process);GO:0070062(extracellular exosome);GO:0043312(neutrophil degranulation);GO:1904813(ficolin-1-rich granule lumen);GO:0035580(specific granule lumen);GO:1904724(tertiary granule lumen);GO:0005160(transforming growth factor beta receptor binding);GO:0001938(positive regulation of endothelial cell proliferation);GO:0030511(positive regulation of transforming growth factor beta receptor signaling pathway);GO:0045766(positive regulation of angiogenesis);GO:0050873(brown fat cell differentiation)","NA","NA","NA","leucine rich alpha-2-glycoprotein 1 [Source:HGNC Symbol;Acc:HGNC:29480]",{"v":0.8929,"d":"0.89"},{"v":24.7987,"d":"24.80"},{"v":0.0360059196651437,"d":"0.04"},{"v":-4.79562207295691,"d":"-4.80"},{"v":6.5454217746068E-10,"d":"0.00"},{"v":1.71972344730722e-07,"d":"0.00"},"down","yes"]
[133677,0,"chr3","+",15003915,15049273,"ENST00000617312",14,8113,"MSTRG.10686","NR2C2","GO:0005634(nucleus);GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0005654(nucleoplasm);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0043565(sequence-specific DNA binding);GO:0003707(steroid hormone receptor activity);GO:0043401(steroid hormone mediated signaling pathway);GO:0030154(cell differentiation);GO:0007283(spermatogenesis);GO:0005515(protein binding);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0001228(transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding);GO:0007399(nervous system development);GO:0003713(transcription coactivator activity);GO:0004872(receptor activity);GO:0046982(protein heterodimerization activity);GO:0006367(transcription initiation from RNA polymerase II promoter);GO:0001077(transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0000977(RNA polymerase II regulatory region sequence-specific DNA binding)","NA","NA","NA","nuclear receptor subfamily 2 group C member 2 [Source:HGNC Symbol;Acc:HGNC:7972]",{"v":0.145955,"d":"0.15"},{"v":4.18848,"d":"4.19"},{"v":0.0348467701887081,"d":"0.03"},{"v":-4.84283124526406,"d":"-4.84"},{"v":6.85503095870518e-10,"d":"0.00"},{"v":1.77767867770682e-07,"d":"0.00"},"down","yes"]
[40390,0,"chr12","+",40225074,40369281,"ENST00000298910",51,9158,"MSTRG.3288","LRRK2","GO:0001934(positive regulation of protein phosphorylation);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0043231(intracellular membrane-bounded organelle);GO:0005525(GTP binding);GO:0007264(small GTPase mediated signal transduction);GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0005634(nucleus);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0005743(mitochondrial inner membrane);GO:0005794(Golgi apparatus);GO:0005783(endoplasmic reticulum);GO:0005739(mitochondrion);GO:0042803(protein homodimerization activity);GO:0043547(positive regulation of GTPase activity);GO:0042995(cell projection);GO:0005515(protein binding);GO:0005615(extracellular space);GO:0030054(cell junction);GO:0045202(synapse);GO:0005741(mitochondrial outer membrane);GO:0030154(cell differentiation);GO:0006914(autophagy);GO:0031410(cytoplasmic vesicle);GO:0005759(mitochondrial matrix);GO:0005096(GTPase activator activity);GO:0005764(lysosome);GO:0030425(dendrite);GO:0042802(identical protein binding);GO:0098794(postsynapse);GO:0005768(endosome);GO:0030424(axon);GO:0005829(cytosol);GO:0048812(neuron projection morphogenesis);GO:0043204(perikaryon);GO:0070062(extracellular exosome);GO:0010508(positive regulation of autophagy);GO:0044325(ion channel binding);GO:0031398(positive regulation of protein ubiquitination);GO:0000165(MAPK cascade);GO:0030276(clathrin binding);GO:0042391(regulation of membrane potential);GO:0046777(protein autophosphorylation);GO:0007005(mitochondrion organization);GO:0030672(synaptic vesicle membrane);GO:0007528(neuromuscular junction development);GO:0032436(positive regulation of proteasomal ubiquitin-dependent protein catabolic process);GO:0060070(canonical Wnt signaling pathway);GO:0030426(growth cone);GO:0043005(neuron projection);GO:0005886(plasma membrane);GO:0043195(terminal bouton);GO:0007030(Golgi organization);GO:1901214(regulation of neuron death);GO:0017048(Rho GTPase binding);GO:0018105(peptidyl-serine phosphorylation);GO:1903206(negative regulation of hydrogen peroxide-induced cell death);GO:0018107(peptidyl-threonine phosphorylation);GO:0034599(cellular response to oxidative stress);GO:1901215(negative regulation of neuron death);GO:1902236(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway);GO:0003779(actin binding);GO:0032092(positive regulation of protein binding);GO:0060828(regulation of canonical Wnt signaling pathway);GO:0071287(cellular response to manganese ion);GO:1902803(regulation of synaptic vesicle transport);GO:1903351(cellular response to dopamine);GO:0043025(neuronal cell body);GO:1990909(Wnt signalosome);GO:0032839(dendrite cytoplasm);GO:0039706(co-receptor binding);GO:0032091(negative regulation of protein binding);GO:0005622(intracellular);GO:1903215(negative regulation of protein targeting to mitochondrion);GO:0006979(response to oxidative stress);GO:0043068(positive regulation of programmed cell death);GO:0015631(tubulin binding);GO:0008340(determination of adult lifespan);GO:0010506(regulation of autophagy);GO:0008017(microtubule binding);GO:0090140(regulation of mitochondrial fission);GO:0009267(cellular response to starvation);GO:0003924(GTPase activity);GO:0046039(GTP metabolic process);GO:2000300(regulation of synaptic vesicle exocytosis);GO:0000149(SNARE binding);GO:0017075(syntaxin-1 binding);GO:0051966(regulation of synaptic transmission, glutamatergic);GO:0061001(regulation of dendritic spine morphogenesis);GO:0000187(activation of MAPK activity);GO:0016242(negative regulation of macroautophagy);GO:0060161(positive regulation of dopamine receptor signaling pathway);GO:0000186(activation of MAPKK activity);GO:0016234(inclusion body);GO:0010955(negative regulation of protein processing);GO:0035556(intracellular signal transduction);GO:0031966(mitochondrial membrane);GO:0006897(endocytosis);GO:0044753(amphisome);GO:0044754(autolysosome);GO:0090263(positive regulation of canonical Wnt signaling pathway);GO:0060079(excitatory postsynaptic potential);GO:1904713(beta-catenin destruction complex binding);GO:0004708(MAP kinase kinase activity);GO:0030159(receptor signaling complex scaffold activity);GO:0034211(GTP-dependent protein kinase activity);GO:0036479(peroxidase inhibitor activity);GO:0051018(protein kinase A binding);GO:0001933(negative regulation of protein phosphorylation);GO:0007040(lysosome organization);GO:0010738(regulation of protein kinase A signaling);GO:0014041(regulation of neuron maturation);GO:0019722(calcium-mediated signaling);GO:0021772(olfactory bulb development);GO:0022028(tangential migration from the subventricular zone to the olfactory bulb);GO:0034260(negative regulation of GTPase activity);GO:0034613(cellular protein localization);GO:0035564(regulation of kidney size);GO:0035640(exploration behavior);GO:0035641(locomotory exploration behavior);GO:0035751(regulation of lysosomal lumen pH);GO:0040012(regulation of locomotion);GO:0043406(positive regulation of MAP kinase activity);GO:0048312(intracellular distribution of mitochondria);GO:0051646(mitochondrion localization);GO:0051900(regulation of mitochondrial depolarization);GO:0060159(regulation of dopamine receptor signaling pathway);GO:0070585(protein localization to mitochondrion);GO:0070997(neuron death);GO:0071407(cellular response to organic cyclic compound);GO:0072593(reactive oxygen species metabolic process);GO:0090394(negative regulation of excitatory postsynaptic potential);GO:1902499(positive regulation of protein autoubiquitination);GO:1902692(regulation of neuroblast proliferation);GO:1902823(negative regulation of late endosome to lysosome transport);GO:1902902(negative regulation of autophagosome assembly);GO:1903125(negative regulation of thioredoxin peroxidase activity by peptidyl-threonine phosphorylation);GO:1903217(negative regulation of protein processing involved in protein targeting to mitochondrion);GO:1904887(Wnt signalosome assembly);GO:1905279(regulation of retrograde transport, endosome to Golgi);GO:1905289(regulation of CAMKK-AMPK signaling cascade);GO:2000172(regulation of branching morphogenesis of a nerve);GO:0005798(Golgi-associated vesicle);GO:0005802(trans-Golgi network);GO:0005902(microvillus);GO:0008021(synaptic vesicle);GO:0030529(intracellular ribonucleoprotein complex);GO:0032473(cytoplasmic side of mitochondrial outer membrane);GO:0045121(membrane raft);GO:0097487(multivesicular body, internal vesicle);GO:0099400(caveola neck)","05012(Parkinson's disease)","K08844","EC:2.7.11.1","leucine rich repeat kinase 2 [Source:HGNC Symbol;Acc:HGNC:18618]",{"v":0.916344,"d":"0.92"},{"v":24.789917,"d":"24.79"},{"v":0.0369643835435189,"d":"0.04"},{"v":-4.75772033611874,"d":"-4.76"},{"v":7.1625605100404e-10,"d":"0.00"},{"v":1.83361549057034e-07,"d":"0.00"},"down","yes"]
[39025,0,"chr12","-",12326056,12350541,"ENST00000535902",4,5831,"ENSG00000111261","MANSC1","GO:0016020(membrane);GO:0016021(integral component of membrane)","NA","NA","NA","MANSC domain containing 1 [Source:HGNC Symbol;Acc:HGNC:25505]",{"v":0.118888,"d":"0.12"},{"v":3.500857,"d":"3.50"},{"v":0.033959684728625,"d":"0.03"},{"v":-4.88003312436318,"d":"-4.88"},{"v":7.28344047852778e-10,"d":"0.00"},{"v":1.84095872753472e-07,"d":"0.00"},"down","yes"]
[94562,"j","chr19","-",2101350,2137093,"MSTRG.7630.5",28,4164,"MSTRG.7630","AP3D1","NA","NA","NA","NA","NA",{"v":8.58051,"d":"8.58"},{"v":0.332322,"d":"0.33"},{"v":25.819867477928,"d":"25.82"},{"v":4.69040969082965,"d":"4.69"},{"v":7.42440447492868E-10,"d":"0.00"},{"v":1.8531313569422E-7,"d":"0.00"},"up","yes"]
[55250,0,"chr14","+",55580317,55684579,"ENST00000395314",44,4618,"MSTRG.4430","KTN1","GO:0003723(RNA binding);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005515(protein binding);GO:0007018(microtubule-based movement);GO:0019894(kinesin binding);GO:0045296(cadherin binding);GO:0044267(cellular protein metabolic process);GO:0043687(post-translational protein modification);GO:0005887(integral component of plasma membrane);GO:0005788(endoplasmic reticulum lumen);GO:0015031(protein transport);GO:0030176(integral component of endoplasmic reticulum membrane)","NA","NA","NA","kinectin 1 [Source:HGNC Symbol;Acc:HGNC:6467]",{"v":0.153162,"d":"0.15"},{"v":4.510561,"d":"4.51"},{"v":0.0339563083173024,"d":"0.03"},{"v":-4.88017657016016,"d":"-4.88"},{"v":7.9726400711902e-10,"d":"0.00"},{"v":1.96540341903118e-07,"d":"0.00"},"down","yes"]
[153595,"j","chr5","-",14708397,14871834,"MSTRG.11977.2",13,4754,"MSTRG.11977","ANKH","NA","NA","NA","NA","NA",{"v":3.824361,"d":"3.82"},{"v":0.143416,"d":"0.14"},{"v":26.6662087912088,"d":"26.67"},{"v":4.73694082240407,"d":"4.74"},{"v":8.11752033062158e-10,"d":"0.00"},{"v":1.97671519465673e-07,"d":"0.00"},"up","yes"]
[76380,0,"chr16","+",84819991,84907112,"ENST00000567845",15,2178,"MSTRG.6199","CRISPLD2","GO:0005576(extracellular region);GO:0005539(glycosaminoglycan binding);GO:0008201(heparin binding);GO:0030198(extracellular matrix organization);GO:0030324(lung development);GO:0005578(proteinaceous extracellular matrix);GO:0070062(extracellular exosome);GO:0043312(neutrophil degranulation);GO:0034774(secretory granule lumen);GO:1904813(ficolin-1-rich granule lumen);GO:0060325(face morphogenesis);GO:0030133(transport vesicle)","NA","NA","NA","cysteine rich secretory protein LCCL domain containing 2 [Source:HGNC Symbol;Acc:HGNC:25248]",{"v":0.370214,"d":"0.37"},{"v":10.507187,"d":"10.51"},{"v":0.0352343591105783,"d":"0.04"},{"v":-4.82687321712249,"d":"-4.83"},{"v":8.48602182385534e-10,"d":"0.00"},{"v":2.04155281661137e-07,"d":"0.00"},"down","yes"]
[76696,0,"chr16","+",88570381,88631966,"ENST00000301011",18,3729,"MSTRG.6225","ZC3H18","GO:0003723(RNA binding);GO:0005634(nucleus);GO:0016607(nuclear speck);GO:0046872(metal ion binding);GO:0005515(protein binding);GO:0043234(protein complex)","NA","NA","NA","zinc finger CCCH-type containing 18 [Source:HGNC Symbol;Acc:HGNC:25091]",{"v":5.688813,"d":"5.69"},{"v":0.218454,"d":"0.22"},{"v":26.0412398033453,"d":"26.04"},{"v":4.70272623062436,"d":"4.70"},{"v":9.23454502320904e-10,"d":"0.00"},{"v":2.19518327408855e-07,"d":"0.00"},"up","yes"]
[159184,0,"chr5","-",140631728,140633701,"ENST00000302014",2,1886,"MSTRG.12388","CD14","GO:0016020(membrane);GO:0005794(Golgi apparatus);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0005615(extracellular space);GO:0031225(anchored component of membrane);GO:0045121(membrane raft);GO:0002376(immune system process);GO:0045087(innate immune response);GO:0006954(inflammatory response);GO:0070062(extracellular exosome);GO:0071222(cellular response to lipopolysaccharide);GO:0010008(endosome membrane);GO:0043312(neutrophil degranulation);GO:0006915(apoptotic process);GO:0002224(toll-like receptor signaling pathway);GO:0002755(MyD88-dependent toll-like receptor signaling pathway);GO:0002756(MyD88-independent toll-like receptor signaling pathway);GO:0007249(I-kappaB kinase/NF-kappaB signaling);GO:0034128(negative regulation of MyD88-independent toll-like receptor signaling pathway);GO:0034142(toll-like receptor 4 signaling pathway);GO:0035666(TRIF-dependent toll-like receptor signaling pathway);GO:0070266(necroptotic process);GO:0097190(apoptotic signaling pathway);GO:0046696(lipopolysaccharide receptor complex);GO:0007166(cell surface receptor signaling pathway);GO:0030667(secretory granule membrane);GO:0038123(toll-like receptor TLR1:TLR2 signaling pathway);GO:0038124(toll-like receptor TLR6:TLR2 signaling pathway);GO:0071223(cellular response to lipoteichoic acid);GO:0071726(cellular response to diacyl bacterial lipopeptide);GO:0071727(cellular response to triacyl bacterial lipopeptide);GO:0032760(positive regulation of tumor necrosis factor production);GO:0032729(positive regulation of interferon-gamma production);GO:0031362(anchored component of external side of plasma membrane);GO:0001530(lipopolysaccharide binding);GO:0001847(opsonin receptor activity);GO:0016019(peptidoglycan receptor activity);GO:0070891(lipoteichoic acid binding);GO:0071723(lipopeptide binding);GO:0002237(response to molecule of bacterial origin);GO:0006898(receptor-mediated endocytosis);GO:0006909(phagocytosis);GO:0009408(response to heat);GO:0009617(response to bacterium);GO:0031663(lipopolysaccharide-mediated signaling pathway);GO:0032026(response to magnesium ion);GO:0032481(positive regulation of type I interferon production);GO:0032496(response to lipopolysaccharide);GO:0034612(response to tumor necrosis factor);GO:0045471(response to ethanol);GO:0045807(positive regulation of endocytosis);GO:0050715(positive regulation of cytokine secretion);GO:0051602(response to electrical stimulus);GO:0071219(cellular response to molecule of bacterial origin);GO:1901224(positive regulation of NIK/NF-kappaB signaling);GO:2000484(positive regulation of interleukin-8 secretion);GO:0009897(external side of plasma membrane);GO:0009986(cell surface)","04010(MAPK signaling pathway);04064(NF-kappa B signaling pathway);04145(Phagosome);04810(Regulation of actin cytoskeleton);04640(Hematopoietic cell lineage);04620(Toll-like receptor signaling pathway);05202(Transcriptional misregulation in cancers);05221(Acute myeloid leukemia);05130(Pathogenic Escherichia coli infection);05132(Salmonella infection);05133(Pertussis);05134(Legionellosis);05152(Tuberculosis);05146(Amoebiasis)","K04391","NA","CD14 molecule [Source:HGNC Symbol;Acc:HGNC:1628]",{"v":1.815346,"d":"1.82"},{"v":47.728111,"d":"47.73"},{"v":0.0380351529102,"d":"0.04"},{"v":-4.71652278474276,"d":"-4.72"},{"v":1.03692987043639E-9,"d":"0.00"},{"v":2.43593125327928e-07,"d":"0.00"},"down","yes"]
[88709,0,"chr17","-",78110458,78128697,"ENST00000590602",20,5268,"MSTRG.7280","TMC6","GO:0006810(transport);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005794(Golgi apparatus);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0006811(ion transport);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0008150(biological_process);GO:0070062(extracellular exosome);GO:0043312(neutrophil degranulation);GO:0035579(specific granule membrane);GO:0070821(tertiary granule membrane);GO:0031965(nuclear membrane)","NA","NA","NA","transmembrane channel like 6 [Source:HGNC Symbol;Acc:HGNC:18021]",{"v":0.149797,"d":"0.15"},{"v":4.173358,"d":"4.17"},{"v":0.0358936376893619,"d":"0.04"},{"v":-4.80012804732686,"d":"-4.80"},{"v":1.08429273040422e-09,"d":"0.00"},{"v":2.51757642333855e-07,"d":"0.00"},"down","yes"]
[116288,0,"chr2","-",170990823,171160833,"ENST00000360843",22,5726,"MSTRG.9228","TLK1","GO:0005634(nucleus);GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0016569(covalent chromatin modification);GO:0005515(protein binding);GO:0006974(cellular response to DNA damage stimulus);GO:0007049(cell cycle);GO:0006886(intracellular protein transport);GO:0035556(intracellular signal transduction);GO:0001672(regulation of chromatin assembly or disassembly)","NA","NA","NA","tousled like kinase 1 [Source:HGNC Symbol;Acc:HGNC:11841]",{"v":3.12331,"d":"3.12"},{"v":0.120094,"d":"0.12"},{"v":26.0072110180359,"d":"26.01"},{"v":4.70083978958592,"d":"4.70"},{"v":1.10175420640721e-09,"d":"0.00"},{"v":2.52871586132635e-07,"d":"0.00"},"up","yes"]
[56438,0,"chr14","+",71529325,71741229,"ENST00000555818",22,7831,"ENSG00000197555","SIPA1L1","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005886(plasma membrane);GO:0005856(cytoskeleton);GO:0005096(GTPase activator activity);GO:0030054(cell junction);GO:0045202(synapse);GO:0045211(postsynaptic membrane);GO:0031532(actin cytoskeleton reorganization);GO:0043087(regulation of GTPase activity);GO:0051056(regulation of small GTPase mediated signal transduction);GO:0003674(molecular_function);GO:0008150(biological_process);GO:0005575(cellular_component);GO:0090630(activation of GTPase activity);GO:0014069(postsynaptic density);GO:0043197(dendritic spine);GO:0048814(regulation of dendrite morphogenesis);GO:0043005(neuron projection);GO:0048167(regulation of synaptic plasticity);GO:0048013(ephrin receptor signaling pathway);GO:0050770(regulation of axonogenesis);GO:0061001(regulation of dendritic spine morphogenesis);GO:0046875(ephrin receptor binding);GO:0043547(positive regulation of GTPase activity)","04015(Rap1 signaling pathway)","K17701","NA","signal induced proliferation associated 1 like 1 [Source:HGNC Symbol;Acc:HGNC:20284]",{"v":0.241241,"d":"0.24"},{"v":6.369204,"d":"6.37"},{"v":0.0378761616051237,"d":"0.04"},{"v":-4.72256605521545,"d":"-4.72"},{"v":1.2426401759708e-09,"d":"0.00"},{"v":2.79612607067186E-7,"d":"0.00"},"down","yes"]
[141795,"j","chr3","+",152243580,152463136,"MSTRG.11286.2",11,3181,"MSTRG.11286","MBNL1","NA","NA","NA","NA","NA",{"v":1.128516,"d":"1.13"},{"v":29.064339,"d":"29.06"},{"v":0.0388282011161513,"d":"0.04"},{"v":-4.68675132004893,"d":"-4.69"},{"v":1.24627013366284E-9,"d":"0.00"},{"v":2.79612607067186E-7,"d":"0.00"},"down","yes"]
[31216,0,"chr11","+",65497762,65506469,"ENST00000534336",1,8708,"MSTRG.2546","MALAT1","NA","NA","NA","NA","metastasis associated lung adenocarcinoma transcript 1 (non-protein coding) [Source:HGNC Symbol;Acc:HGNC:29665]",{"v":52.667068,"d":"52.67"},{"v":2.279201,"d":"2.28"},{"v":23.1076890541905,"d":"23.11"},{"v":4.53030108135817,"d":"4.53"},{"v":1.3852151055635e-09,"d":"0.00"},{"v":3.0733305808769E-7,"d":"0.00"},"up","yes"]
[11832,0,"chr1","+",155689083,155738526,"ENST00000343043",13,1649,"MSTRG.1064","DAP3","GO:0003723(RNA binding);GO:0000166(nucleotide binding);GO:0005654(nucleoplasm);GO:0005739(mitochondrion);GO:0030529(intracellular ribonucleoprotein complex);GO:0005840(ribosome);GO:0005525(GTP binding);GO:0015935(small ribosomal subunit);GO:0006915(apoptotic process);GO:0005515(protein binding);GO:0005761(mitochondrial ribosome);GO:0003735(structural constituent of ribosome);GO:0005763(mitochondrial small ribosomal subunit);GO:0005743(mitochondrial inner membrane);GO:0070125(mitochondrial translational elongation);GO:0070126(mitochondrial translational termination);GO:0097190(apoptotic signaling pathway)","NA","NA","NA","death associated protein 3 [Source:HGNC Symbol;Acc:HGNC:2673]",{"v":11.90317,"d":"11.90"},{"v":0.481616,"d":"0.48"},{"v":24.7150634530414,"d":"24.72"},{"v":4.62731870532097,"d":"4.63"},{"v":1.45187057366762e-09,"d":"0.00"},{"v":3.15517740636332e-07,"d":"0.00"},"up","yes"]
[112971,"j","chr2","+",101697931,101891869,"MSTRG.9017.8",30,4430,"MSTRG.9017","MAP4K4","NA","NA","NA","NA","NA",{"v":15.180919,"d":"15.18"},{"v":0.644037,"d":"0.64"},{"v":23.5715013267871,"d":"23.57"},{"v":4.55897174519082,"d":"4.56"},{"v":1.45370753898951e-09,"d":"0.00"},{"v":3.15517740636332e-07,"d":"0.00"},"up","yes"]
[176478,"j","chr7","+",99374658,99394795,"MSTRG.13793.13",11,1644,"MSTRG.13793","AC004922.1","NA","NA","NA","NA","NA",{"v":0.494723,"d":"0.49"},{"v":13.418343,"d":"13.42"},{"v":0.0368691573914901,"d":"0.04"},{"v":-4.76144174434949,"d":"-4.76"},{"v":1.53214334396494E-9,"d":"0.00"},{"v":3.28966003142924e-07,"d":"0.00"},"down","yes"]
[36867,0,"chr11","+",128694092,128813267,"ENST00000534087",10,3859,"MSTRG.2969","FLI1","GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0006355(regulation of transcription, DNA-templated);GO:0005634(nucleus);GO:0043565(sequence-specific DNA binding);GO:0005829(cytosol);GO:0006366(transcription from RNA polymerase II promoter);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0016604(nuclear body);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:0000980(RNA polymerase II distal enhancer sequence-specific DNA binding);GO:0001077(transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0003682(chromatin binding);GO:0008015(blood circulation);GO:0009887(animal organ morphogenesis);GO:0035855(megakaryocyte development);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0045893(positive regulation of transcription, DNA-templated);GO:0000981(RNA polymerase II transcription factor activity, sequence-specific DNA binding);GO:0030154(cell differentiation);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0007599(hemostasis)","05202(Transcriptional misregulation in cancers)","K09436","NA","Fli-1 proto-oncogene, ETS transcription factor [Source:HGNC Symbol;Acc:HGNC:3749]",{"v":0.536303,"d":"0.54"},{"v":13.664317,"d":"13.66"},{"v":0.0392484307850879,"d":"0.04"},{"v":-4.671221215868,"d":"-4.67"},{"v":1.64872632288489e-09,"d":"0.00"},{"v":3.5023156612091e-07,"d":"0.00"},"down","yes"]
[81486,0,"chr17","-",29071124,29180412,"ENST00000527372",42,9992,"MSTRG.6598","MYO18A","GO:0003723(RNA binding);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0003677(DNA binding);GO:0051015(actin filament binding);GO:0006259(DNA metabolic process);GO:0016459(myosin complex);GO:0005794(Golgi apparatus);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0000139(Golgi membrane);GO:0005802(trans-Golgi network);GO:0009986(cell surface);GO:0043066(negative regulation of apoptotic process);GO:0016477(cell migration);GO:0050714(positive regulation of protein secretion);GO:0007030(Golgi organization);GO:0005793(endoplasmic reticulum-Golgi intermediate compartment);GO:0043030(regulation of macrophage activation);GO:0043531(ADP binding);GO:0031032(actomyosin structure organization);GO:0042641(actomyosin);GO:0048194(Golgi vesicle budding);GO:0090161(Golgi ribbon formation);GO:0090164(asymmetric Golgi ribbon formation);GO:1903028(positive regulation of opsonization);GO:0003774(motor activity);GO:0008094(DNA-dependent ATPase activity)","NA","NA","NA","myosin XVIIIA [Source:HGNC Symbol;Acc:HGNC:31104]",{"v":3.963186,"d":"3.96"},{"v":0.169318,"d":"0.17"},{"v":23.4067612421597,"d":"23.41"},{"v":4.5488534196352,"d":"4.55"},{"v":1.7186306987258e-09,"d":"0.00"},{"v":3.61238082022703e-07,"d":"0.00"},"up","yes"]
[181910,0,"chr8","+",22053570,22082524,"ENST00000381470",15,2601,"MSTRG.14210","DMTN","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0003779(actin binding);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0051693(actin filament capping);GO:0005856(cytoskeleton);GO:0042995(cell projection);GO:0005515(protein binding);GO:0048471(perinuclear region of cytoplasm);GO:0031410(cytoplasmic vesicle);GO:0007010(cytoskeleton organization);GO:0032956(regulation of actin cytoskeleton organization);GO:0055085(transmembrane transport);GO:0012505(endomembrane system);GO:0005102(receptor binding);GO:0008360(regulation of cell shape);GO:0051017(actin filament bundle assembly);GO:0030036(actin cytoskeleton organization);GO:0005884(actin filament);GO:0051895(negative regulation of focal adhesion assembly);GO:0090315(negative regulation of protein targeting to membrane);GO:1900025(negative regulation of substrate adhesion-dependent cell spreading);GO:0006461(protein complex assembly);GO:0015629(actin cytoskeleton);GO:0071320(cellular response to cAMP);GO:0071277(cellular response to calcium ion);GO:0035584(calcium-mediated signaling using intracellular calcium source);GO:0051489(regulation of filopodium assembly);GO:1900026(positive regulation of substrate adhesion-dependent cell spreading);GO:0090303(positive regulation of wound healing);GO:0090527(actin filament reorganization);GO:2001046(positive regulation of integrin-mediated signaling pathway);GO:0033137(negative regulation of peptidyl-serine phosphorylation);GO:0030507(spectrin binding);GO:0010591(regulation of lamellipodium assembly);GO:0048821(erythrocyte development);GO:0010763(positive regulation of fibroblast migration);GO:0010801(negative regulation of peptidyl-threonine phosphorylation);GO:0010812(negative regulation of cell-substrate adhesion);GO:0030194(positive regulation of blood coagulation);GO:0035585(calcium-mediated signaling using extracellular calcium source);GO:0050732(negative regulation of peptidyl-tyrosine phosphorylation);GO:0070560(protein secretion by platelet);GO:1901731(positive regulation of platelet aggregation);GO:0014731(spectrin-associated cytoskeleton);GO:0031095(platelet dense tubular network membrane);GO:0031253(cell projection membrane);GO:0043621(protein self-association);GO:0014069(postsynaptic density);GO:0030863(cortical cytoskeleton)","NA","NA","NA","dematin actin binding protein [Source:HGNC Symbol;Acc:HGNC:3382]",{"v":12.840851,"d":"12.84"},{"v":0.546032,"d":"0.55"},{"v":23.5166638585284,"d":"23.52"},{"v":4.55561150471572,"d":"4.56"},{"v":1.75206775502344E-9,"d":"0.00"},{"v":3.64430093044876e-07,"d":"0.00"},"up","yes"]
[182240,"j","chr8","+",23541445,23572237,"MSTRG.14243.10",4,4727,"MSTRG.14243","SLC25A37","NA","NA","NA","NA","NA",{"v":25.833742,"d":"25.83"},{"v":1.138456,"d":"1.14"},{"v":22.691910798485,"d":"22.69"},{"v":4.50410619281033,"d":"4.50"},{"v":1.81410688569583e-09,"d":"0.00"},{"v":3.7144353265178e-07,"d":"0.00"},"up","yes"]
[192851,"j","chr9","-",114337207,114377532,"MSTRG.14926.9",18,4559,"MSTRG.14926","AKNA","NA","NA","NA","NA","NA",{"v":0.290066,"d":"0.29"},{"v":7.400884,"d":"7.40"},{"v":0.0391934260826139,"d":"0.04"},{"v":-4.67324449853008,"d":"-4.67"},{"v":1.82299009414435e-09,"d":"0.00"},{"v":3.7144353265178e-07,"d":"0.00"},"down","yes"]
[148285,0,"chr4","-",75642782,75673969,"ENST00000359707",12,4883,"MSTRG.11660","G3BP2","GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0006810(transport);GO:0051028(mRNA transport);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005622(intracellular);GO:0005515(protein binding);GO:0034063(stress granule assembly);GO:0007265(Ras protein signal transduction);GO:0003729(mRNA binding);GO:0030159(receptor signaling complex scaffold activity);GO:0007253(cytoplasmic sequestering of NF-kappaB);GO:0030529(intracellular ribonucleoprotein complex)","NA","NA","NA","G3BP stress granule assembly factor 2 [Source:HGNC Symbol;Acc:HGNC:30291]",{"v":0.240093,"d":"0.24"},{"v":6.16063,"d":"6.16"},{"v":0.0389721505755093,"d":"0.04"},{"v":-4.68141264474415,"d":"-4.68"},{"v":1.93827650933372e-09,"d":"0.00"},{"v":3.8750046120137e-07,"d":"0.00"},"down","yes"]
[41210,0,"chr12","-",49185010,49186864,"ENST00000550767",3,1384,"MSTRG.3349","TUBA1A","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005525(GTP binding);GO:0000166(nucleotide binding);GO:0003924(GTPase activity);GO:0015630(microtubule cytoskeleton);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0005200(structural constituent of cytoskeleton);GO:0007010(cytoskeleton organization);GO:0005874(microtubule);GO:0007017(microtubule-based process);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0055037(recycling endosome);GO:0000086(G2/M transition of mitotic cell cycle);GO:0010389(regulation of G2/M transition of mitotic cell cycle);GO:0097711(ciliary basal body docking);GO:0036464(cytoplasmic ribonucleoprotein granule);GO:0005198(structural molecule activity);GO:0030705(cytoskeleton-dependent intracellular transport);GO:0051301(cell division);GO:0019904(protein domain specific binding);GO:0005881(cytoplasmic microtubule);GO:0043209(myelin sheath);GO:0045121(membrane raft)","04145(Phagosome);04210(Apoptosis);04530(Tight junction);04540(Gap junction);05130(Pathogenic Escherichia coli infection)","K07374","NA","tubulin alpha 1a [Source:HGNC Symbol;Acc:HGNC:20766]",{"v":16.328503,"d":"16.33"},{"v":0.685768,"d":"0.69"},{"v":23.8105350497544,"d":"23.81"},{"v":4.57352813485531,"d":"4.57"},{"v":1.94060727765109e-09,"d":"0.00"},{"v":3.8750046120137e-07,"d":"0.00"},"up","yes"]
[160042,0,"chr5","-",150401637,150412769,"ENST00000377795",6,1138,"MSTRG.12456","CD74","GO:0070374(positive regulation of ERK1 and ERK2 cascade);GO:0048146(positive regulation of fibroblast proliferation);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0006886(intracellular protein transport);GO:0005794(Golgi apparatus);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0007165(signal transduction);GO:0006955(immune response);GO:0002376(immune system process);GO:0005764(lysosome);GO:0002250(adaptive immune response);GO:0050900(leukocyte migration);GO:0019882(antigen processing and presentation);GO:0005768(endosome);GO:0070062(extracellular exosome);GO:0005622(intracellular);GO:0008283(cell proliferation);GO:0042802(identical protein binding);GO:0042289(MHC class II protein binding);GO:0019886(antigen processing and presentation of exogenous peptide antigen via MHC class II);GO:0009986(cell surface);GO:0043066(negative regulation of apoptotic process);GO:0050731(positive regulation of peptidyl-tyrosine phosphorylation);GO:0032588(trans-Golgi network membrane);GO:0000139(Golgi membrane);GO:0030666(endocytic vesicle membrane);GO:0043202(lysosomal lumen);GO:0090023(positive regulation of neutrophil chemotaxis);GO:0012507(ER to Golgi transport vesicle membrane);GO:0005765(lysosomal membrane);GO:0001516(prostaglandin biosynthetic process);GO:0019955(cytokine binding);GO:0006461(protein complex assembly);GO:0045893(positive regulation of transcription, DNA-templated);GO:0001961(positive regulation of cytokine-mediated signaling pathway);GO:0071556(integral component of lumenal side of endoplasmic reticulum membrane);GO:0043518(negative regulation of DNA damage response, signal transduction by p53 class mediator);GO:1902166(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator);GO:0030669(clathrin-coated endocytic vesicle membrane);GO:0030658(transport vesicle membrane);GO:0001540(amyloid-beta binding);GO:2000343(positive regulation of chemokine (C-X-C motif) ligand 2 production);GO:0001934(positive regulation of protein phosphorylation);GO:0033674(positive regulation of kinase activity);GO:0043123(positive regulation of I-kappaB kinase/NF-kappaB signaling);GO:0043410(positive regulation of MAPK cascade);GO:0045058(T cell selection);GO:0045657(positive regulation of monocyte differentiation);GO:0046598(positive regulation of viral entry into host cell);GO:0051290(protein heterotetramerization);GO:0023026(MHC class II protein complex binding);GO:0042613(MHC class II protein complex);GO:0004896(cytokine receptor activity);GO:0035718(macrophage migration inhibitory factor binding);GO:0042609(CD4 receptor binding);GO:0042658(MHC class II protein binding, via antigen binding groove);GO:0044183(protein binding involved in protein folding);GO:0002792(negative regulation of peptide secretion);GO:0016064(immunoglobulin mediated immune response);GO:0019883(antigen processing and presentation of endogenous antigen);GO:0030890(positive regulation of B cell proliferation);GO:0043030(regulation of macrophage activation);GO:0060907(positive regulation of macrophage cytokine production);GO:0005773(vacuole);GO:0035692(macrophage migration inhibitory factor receptor complex);GO:0050998(nitric-oxide synthase binding);GO:0000187(activation of MAPK activity);GO:0002606(positive regulation of dendritic cell antigen processing and presentation);GO:0002830(positive regulation of type 2 immune response);GO:0002906(negative regulation of mature B cell apoptotic process);GO:0006952(defense response);GO:0035691(macrophage migration inhibitory factor signaling pathway);GO:0045059(positive thymic T cell selection);GO:0045060(negative thymic T cell selection);GO:0045581(negative regulation of T cell differentiation);GO:0045582(positive regulation of T cell differentiation);GO:0051085(chaperone mediated protein folding requiring cofactor);GO:0005770(late endosome);GO:0005771(multivesicular body);GO:0009897(external side of plasma membrane);GO:0035693(NOS2-CD74 complex)","04612(Antigen processing and presentation);05152(Tuberculosis);05168(Herpes simplex infection)","K06505","NA","CD74 molecule [Source:HGNC Symbol;Acc:HGNC:1697]",{"v":8.848909,"d":"8.85"},{"v":212.439621,"d":"212.44"},{"v":0.041653760058252,"d":"0.04"},{"v":-4.58540945714794,"d":"-4.59"},{"v":2.13244537325867E-9,"d":"0.00"},{"v":4.21590784289398e-07,"d":"0.00"},"down","yes"]
[149255,"j","chr4","+",88592423,88720331,"MSTRG.11726.5",30,4930,"MSTRG.11726","HERC3","NA","NA","NA","NA","NA",{"v":0.375988,"d":"0.38"},{"v":9.231418,"d":"9.23"},{"v":0.040729170751449,"d":"0.04"},{"v":-4.61779374849873,"d":"-4.62"},{"v":2.31137793539389e-09,"d":"0.00"},{"v":4.48754738430572e-07,"d":"0.00"},"down","yes"]
[52662,0,"chr14","-",21385486,21456080,"ENST00000557364",38,8137,"MSTRG.4144","CHD8","GO:0005634(nucleus);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0005654(nucleoplasm);GO:0016787(hydrolase activity);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0016569(covalent chromatin modification);GO:0004386(helicase activity);GO:0032508(DNA duplex unwinding);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0043044(ATP-dependent chromatin remodeling);GO:0016055(Wnt signaling pathway);GO:0045893(positive regulation of transcription, DNA-templated);GO:0016817(hydrolase activity, acting on acid anhydrides);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0030178(negative regulation of Wnt signaling pathway);GO:0043234(protein complex);GO:0042393(histone binding);GO:0045892(negative regulation of transcription, DNA-templated);GO:0071339(MLL1 complex);GO:0008013(beta-catenin binding);GO:0007420(brain development);GO:0035064(methylated histone binding);GO:0002039(p53 binding);GO:0060070(canonical Wnt signaling pathway);GO:0008094(DNA-dependent ATPase activity);GO:0090090(negative regulation of canonical Wnt signaling pathway);GO:0003682(chromatin binding);GO:0003678(DNA helicase activity);GO:0045945(positive regulation of transcription from RNA polymerase III promoter);GO:0048565(digestive tract development);GO:0070016(armadillo repeat domain binding);GO:0001701(in utero embryonic development);GO:0043066(negative regulation of apoptotic process);GO:2000270(negative regulation of fibroblast apoptotic process)","04310(Wnt signaling pathway)","NA","NA","chromodomain helicase DNA binding protein 8 [Source:HGNC Symbol;Acc:HGNC:20153]",{"v":0.089615,"d":"0.09"},{"v":2.316355,"d":"2.32"},{"v":0.0386879385931776,"d":"0.04"},{"v":-4.69197232996826,"d":"-4.69"},{"v":2.31479056782597e-09,"d":"0.00"},{"v":4.48754738430572e-07,"d":"0.00"},"down","yes"]
[153661,0,"chr5","+",17217560,17276834,"ENST00000322611",2,1878,"MSTRG.11980","BASP1","GO:0005886(plasma membrane);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016607(nuclear speck);GO:0016020(membrane);GO:0030054(cell junction);GO:0042995(cell projection);GO:0005515(protein binding);GO:0003714(transcription corepressor activity);GO:0030426(growth cone);GO:0070062(extracellular exosome);GO:0008180(COP9 signalosome);GO:0021762(substantia nigra development);GO:0019904(protein domain specific binding);GO:0044212(transcription regulatory region DNA binding);GO:0045892(negative regulation of transcription, DNA-templated);GO:0005856(cytoskeleton);GO:0031982(vesicle);GO:0072112(glomerular visceral epithelial cell differentiation);GO:0060539(diaphragm development);GO:0007356(thorax and anterior abdomen determination);GO:0008406(gonad development);GO:0060231(mesenchymal to epithelial transition);GO:0060421(positive regulation of heart growth);GO:0072075(metanephric mesenchyme development);GO:2001076(positive regulation of metanephric ureteric bud development)","NA","NA","NA","brain abundant membrane attached signal protein 1 [Source:HGNC Symbol;Acc:HGNC:957]",{"v":4.187995,"d":"4.19"},{"v":99.764618,"d":"99.76"},{"v":0.0419787604459128,"d":"0.04"},{"v":-4.57419662259527,"d":"-4.57"},{"v":2.35643109527237e-09,"d":"0.00"},{"v":4.52434770292295E-7,"d":"0.00"},"down","yes"]
[166721,0,"chr6","-",53267398,53349179,"ENST00000370918",9,3081,"MSTRG.13091","ELOVL5","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005783(endoplasmic reticulum);GO:0016740(transferase activity);GO:0006629(lipid metabolic process);GO:0005789(endoplasmic reticulum membrane);GO:0009922(fatty acid elongase activity);GO:0102336(3-oxo-arachidoyl-CoA synthase activity);GO:0102337(3-oxo-cerotoyl-CoA synthase activity);GO:0102338(3-oxo-lignoceronyl-CoA synthase activity);GO:0006631(fatty acid metabolic process);GO:0006633(fatty acid biosynthetic process);GO:0006636(unsaturated fatty acid biosynthetic process);GO:0019367(fatty acid elongation, saturated fatty acid);GO:0034626(fatty acid elongation, polyunsaturated fatty acid);GO:0042761(very long-chain fatty acid biosynthetic process);GO:0042995(cell projection);GO:0034625(fatty acid elongation, monounsaturated fatty acid);GO:0035338(long-chain fatty-acyl-CoA biosynthetic process);GO:0030425(dendrite);GO:0005515(protein binding);GO:0030148(sphingolipid biosynthetic process);GO:0030176(integral component of endoplasmic reticulum membrane);GO:0036109(alpha-linolenic acid metabolic process);GO:0043025(neuronal cell body);GO:0043651(linoleic acid metabolic process);GO:0045723(positive regulation of fatty acid biosynthetic process);GO:0097447(dendritic tree)","00062(Fatty acid elongation);01040(Biosynthesis of unsaturated fatty acids)","K10244","EC:2.3.1.199","ELOVL fatty acid elongase 5 [Source:HGNC Symbol;Acc:HGNC:21308]",{"v":5.413077,"d":"5.41"},{"v":0.229399,"d":"0.23"},{"v":23.5967767950165,"d":"23.60"},{"v":4.56051790280407,"d":"4.56"},{"v":2.44414767107272e-09,"d":"0.00"},{"v":4.64807054247429e-07,"d":"0.00"},"up","yes"]
[42173,0,"chr12","+",53380639,53416446,"ENST00000426431",6,7603,"MSTRG.3397","SP1","GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0005654(nucleoplasm);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0042803(protein homodimerization activity);GO:0005515(protein binding);GO:0048511(rhythmic process);GO:0045893(positive regulation of transcription, DNA-templated);GO:0016032(viral process);GO:0008022(protein C-terminus binding);GO:0008134(transcription factor binding);GO:0043425(bHLH transcription factor binding);GO:0000790(nuclear chromatin);GO:0000982(transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0042795(snRNA transcription from RNA polymerase II promoter);GO:0044212(transcription regulatory region DNA binding);GO:0001046(core promoter sequence-specific DNA binding);GO:0045540(regulation of cholesterol biosynthetic process);GO:0000977(RNA polymerase II regulatory region sequence-specific DNA binding);GO:0001103(RNA polymerase II repressing transcription factor binding);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:0042826(histone deacetylase binding);GO:0043923(positive regulation by host of viral transcription);GO:0001077(transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0003690(double-stranded DNA binding);GO:0035035(histone acetyltransferase binding);GO:0043565(sequence-specific DNA binding);GO:0070491(repressing transcription factor binding);GO:0071837(HMG box domain binding);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0032869(cellular response to insulin stimulus);GO:0100057(regulation of phenotypic switching by transcription from RNA polymerase II promoter);GO:1904828(positive regulation of hydrogen sulfide biosynthetic process);GO:0017053(transcriptional repressor complex);GO:0032993(protein-DNA complex)","04350(TGF-beta signaling pathway);04137(Mitophagy - animal);04915(Estrogen signaling pathway);04927(Cortisol synthesis and secretion);05200(Pathways in cancer);05231(Choline metabolism in cancer);05202(Transcriptional misregulation in cancers);05224(Breast cancer);05016(Huntington's disease);01522(Endocrine resistance)","K04684","NA","Sp1 transcription factor [Source:HGNC Symbol;Acc:HGNC:11205]",{"v":0.576275,"d":"0.58"},{"v":13.66888,"d":"13.67"},{"v":0.0421596356102329,"d":"0.04"},{"v":-4.56799379209708,"d":"-4.57"},{"v":2.54104143441246e-09,"d":"0.00"},{"v":4.78674673229697e-07,"d":"0.00"},"down","yes"]
[146735,"j","chr4","-",38795974,38845886,"MSTRG.11573.6",8,6273,"MSTRG.11573","TLR1","NA","NA","NA","NA","NA",{"v":4.91326,"d":"4.91"},{"v":0.220835,"d":"0.22"},{"v":22.2485566146671,"d":"22.25"},{"v":4.47563983849864,"d":"4.48"},{"v":2.91856741236892E-9,"d":"0.00"},{"v":5.44653776543762e-07,"d":"0.00"},"up","yes"]
[194738,0,"chr9","-",136114581,136118863,"ENST00000418388",2,2823,"MSTRG.15092","TMEM250","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005654(nucleoplasm);GO:0005515(protein binding);GO:0007049(cell cycle);GO:0016032(viral process);GO:0008284(positive regulation of cell proliferation);GO:0048524(positive regulation of viral process)","NA","NA","NA","transmembrane protein 250 [Source:HGNC Symbol;Acc:HGNC:31009]",{"v":8.543703,"d":"8.54"},{"v":0.377317,"d":"0.38"},{"v":22.6433025811188,"d":"22.64"},{"v":4.50101248900768,"d":"4.50"},{"v":3.06828342869702E-9,"d":"0.00"},{"v":5.67291513927981E-7,"d":"0.00"},"up","yes"]
[85658,"j","chr17","+",50719580,50750996,"MSTRG.7029.5",13,1966,"MSTRG.7029","LUC7L3","NA","NA","NA","NA","NA",{"v":11.516099,"d":"11.52"},{"v":0.513972,"d":"0.51"},{"v":22.4060824325061,"d":"22.41"},{"v":4.48581851931517,"d":"4.49"},{"v":3.27835803705202e-09,"d":"0.00"},{"v":5.9614352954595e-07,"d":"0.00"},"up","yes"]
[1020,0,"chr1","-",6186723,6199553,"ENST00000465387",4,508,"MSTRG.98","RPL22","GO:0005622(intracellular);GO:0003735(structural constituent of ribosome);GO:0006412(translation);GO:0005840(ribosome);GO:0003723(RNA binding);GO:0005634(nucleus);GO:0030529(intracellular ribonucleoprotein complex);GO:0005515(protein binding);GO:0005925(focal adhesion);GO:0008201(heparin binding);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0031012(extracellular matrix);GO:0002181(cytoplasmic translation);GO:0005737(cytoplasm);GO:0006413(translational initiation);GO:0006364(rRNA processing);GO:0000184(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay);GO:0019083(viral transcription);GO:0006614(SRP-dependent cotranslational protein targeting to membrane);GO:0022625(cytosolic large ribosomal subunit)","03010(Ribosome)","NA","NA","ribosomal protein L22 [Source:HGNC Symbol;Acc:HGNC:10315]",{"v":63.481682,"d":"63.48"},{"v":2.878353,"d":"2.88"},{"v":22.0548633194052,"d":"22.05"},{"v":4.46302491453185,"d":"4.46"},{"v":3.28404388271507e-09,"d":"0.00"},{"v":5.9614352954595e-07,"d":"0.00"},"up","yes"]
[170564,0,"chr6","-",159679116,159693228,"ENST00000367054",5,815,"MSTRG.13403","SOD2","GO:0046872(metal ion binding);GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0004784(superoxide dismutase activity);GO:0006801(superoxide metabolic process);GO:0003677(DNA binding);GO:0019825(oxygen binding);GO:0019899(enzyme binding);GO:0030145(manganese ion binding);GO:0042802(identical protein binding);GO:0000302(response to reactive oxygen species);GO:0000303(response to superoxide);GO:0001306(age-dependent response to oxidative stress);GO:0001666(response to hypoxia);GO:0001836(release of cytochrome c from mitochondria);GO:0001889(liver development);GO:0003032(detection of oxygen);GO:0003069(acetylcholine-mediated vasodilation involved in regulation of systemic arterial blood pressure);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0006749(glutathione metabolic process);GO:0006979(response to oxidative stress);GO:0007005(mitochondrion organization);GO:0007507(heart development);GO:0007568(aging);GO:0007626(locomotory behavior);GO:0008217(regulation of blood pressure);GO:0008630(intrinsic apoptotic signaling pathway in response to DNA damage);GO:0008631(intrinsic apoptotic signaling pathway in response to oxidative stress);GO:0008637(apoptotic mitochondrial changes);GO:0009314(response to radiation);GO:0009409(response to cold);GO:0009791(post-embryonic development);GO:0010042(response to manganese ion);GO:0010043(response to zinc ion);GO:0010269(response to selenium ion);GO:0010332(response to gamma radiation);GO:0014823(response to activity);GO:0019430(removal of superoxide radicals);GO:0022904(respiratory electron transport chain);GO:0030097(hemopoiesis);GO:0031667(response to nutrient levels);GO:0032496(response to lipopolysaccharide);GO:0033591(response to L-ascorbic acid);GO:0034021(response to silicon dioxide);GO:0035900(response to isolation stress);GO:0035902(response to immobilization stress);GO:0042311(vasodilation);GO:0042493(response to drug);GO:0042542(response to hydrogen peroxide);GO:0042554(superoxide anion generation);GO:0042743(hydrogen peroxide metabolic process);GO:0043066(negative regulation of apoptotic process);GO:0045429(positive regulation of nitric oxide biosynthetic process);GO:0045599(negative regulation of fat cell differentiation);GO:0046686(response to cadmium ion);GO:0048147(negative regulation of fibroblast proliferation);GO:0048666(neuron development);GO:0048678(response to axon injury);GO:0048773(erythrophore differentiation);GO:0050665(hydrogen peroxide biosynthetic process);GO:0050790(regulation of catalytic activity);GO:0051260(protein homooligomerization);GO:0051602(response to electrical stimulus);GO:0051881(regulation of mitochondrial membrane potential);GO:0055072(iron ion homeostasis);GO:0055093(response to hyperoxia);GO:0071000(response to magnetism);GO:0071361(cellular response to ethanol);GO:0005737(cytoplasm);GO:0005739(mitochondrion);GO:0005743(mitochondrial inner membrane);GO:0042645(mitochondrial nucleoid);GO:0043209(myelin sheath);GO:0008285(negative regulation of cell proliferation);GO:0030335(positive regulation of cell migration);GO:0005759(mitochondrial matrix);GO:0070062(extracellular exosome);GO:0035722(interleukin-12-mediated signaling pathway);GO:0051289(protein homotetramerization);GO:0034599(cellular response to oxidative stress);GO:0043524(negative regulation of neuron apoptotic process);GO:1902176(negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway);GO:0001315(age-dependent response to reactive oxygen species);GO:0032364(oxygen homeostasis)","04068(FoxO signaling pathway);04146(Peroxisome);04211(Longevity regulating pathway - mammal);04213(Longevity regulating pathway - multiple species);05016(Huntington's disease)","K04564","EC:1.15.1.1","superoxide dismutase 2 [Source:HGNC Symbol;Acc:HGNC:11180]",{"v":2.196367,"d":"2.20"},{"v":51.834435,"d":"51.83"},{"v":0.0423727392803645,"d":"0.04"},{"v":-4.56071979181511,"d":"-4.56"},{"v":3.44388638213344E-9,"d":"0.00"},{"v":6.19527236742707e-07,"d":"0.00"},"down","yes"]
[123183,0,"chr20","-",35277342,35278129,"ENST00000456790",2,712,"MSTRG.9692","MMP24-AS1","NA","NA","NA","NA","MMP24 antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:44421]",{"v":30.11322,"d":"30.11"},{"v":1.36551,"d":"1.37"},{"v":22.0527275523431,"d":"22.05"},{"v":4.46288519887337,"d":"4.46"},{"v":3.9162979178483e-09,"d":"0.00"},{"v":6.9821997163924e-07,"d":"0.00"},"up","yes"]
[48181,0,"chr12","-",124324415,124495252,"ENST00000405201",47,8533,"ENSG00000196498","NCOR2","GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0003677(DNA binding);GO:0001012(RNA polymerase II regulatory region DNA binding);GO:0003682(chromatin binding);GO:0016922(ligand-dependent nuclear receptor binding);GO:0032403(protein complex binding);GO:0035259(glucocorticoid receptor binding);GO:0042974(retinoic acid receptor binding);GO:0046965(retinoid X receptor binding);GO:0007595(lactation);GO:0010243(response to organonitrogen compound);GO:0032355(response to estradiol);GO:0044849(estrous cycle);GO:0000785(chromatin);GO:0016020(membrane);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0005515(protein binding);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0003714(transcription corepressor activity);GO:0008134(transcription factor binding);GO:0047485(protein N-terminus binding);GO:0000790(nuclear chromatin);GO:0016363(nuclear matrix);GO:0005112(Notch binding);GO:0042826(histone deacetylase binding);GO:0019216(regulation of lipid metabolic process);GO:0017053(transcriptional repressor complex);GO:1903799(negative regulation of production of miRNAs involved in gene silencing by miRNA);GO:0000118(histone deacetylase complex);GO:0072365(regulation of cellular ketone metabolic process by negative regulation of transcription from RNA polymerase II promoter);GO:0016604(nuclear body)","04330(Notch signaling pathway);05169(Epstein-Barr virus infection)","K06065","NA","nuclear receptor corepressor 2 [Source:HGNC Symbol;Acc:HGNC:7673]",{"v":6.092183,"d":"6.09"},{"v":0.292824,"d":"0.29"},{"v":20.8049306067809,"d":"20.80"},{"v":4.37885357128157,"d":"4.38"},{"v":4.68702236723852e-09,"d":"0.00"},{"v":8.28234182557689e-07,"d":"0.00"},"up","yes"]
[48931,0,"chr13","+",19958670,20091829,"ENST00000610343",25,10200,"ENSG00000121741","ZMYM2","GO:0005634(nucleus);GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0018108(peptidyl-tyrosine phosphorylation);GO:0005515(protein binding);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0005737(cytoplasm);GO:0008150(biological_process);GO:0005829(cytosol);GO:0000981(RNA polymerase II transcription factor activity, sequence-specific DNA binding);GO:0007275(multicellular organism development);GO:0003677(DNA binding);GO:0016605(PML body);GO:0004713(protein tyrosine kinase activity);GO:0007010(cytoskeleton organization);GO:0031624(ubiquitin conjugating enzyme binding);GO:0022604(regulation of cell morphogenesis)","NA","NA","NA","zinc finger MYM-type containing 2 [Source:HGNC Symbol;Acc:HGNC:12989]",{"v":0.098836,"d":"0.10"},{"v":2.319617,"d":"2.32"},{"v":0.0426087582562121,"d":"0.04"},{"v":-4.55270618199736,"d":"-4.55"},{"v":4.73756603387704e-09,"d":"0.00"},{"v":8.28407123270896e-07,"d":"0.00"},"down","yes"]
[4910,0,"chr1","+",42682987,42702349,"ENST00000436427",7,1524,"MSTRG.472","YBX1","GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0006397(mRNA processing);GO:0008380(RNA splicing);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0043231(intracellular membrane-bounded organelle);GO:0005829(cytosol);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0031965(nuclear membrane);GO:0030529(intracellular ribonucleoprotein complex);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:0005654(nucleoplasm);GO:0070062(extracellular exosome);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0010494(cytoplasmic stress granule);GO:0006366(transcription from RNA polymerase II promoter);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:1903608(protein localization to cytoplasmic stress granule);GO:0001077(transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0051781(positive regulation of cell division);GO:0000398(mRNA splicing, via spliceosome);GO:0070934(CRD-mediated mRNA stabilization);GO:0070937(CRD-mediated mRNA stability complex);GO:0071204(histone pre-mRNA 3'end processing complex);GO:0051020(GTPase binding);GO:0005689(U12-type spliceosomal complex);GO:0003690(double-stranded DNA binding);GO:0003697(single-stranded DNA binding);GO:0003682(chromatin binding);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0001701(in utero embryonic development);GO:0051154(negative regulation of striated muscle cell differentiation)","NA","NA","NA","Y-box binding protein 1 [Source:HGNC Symbol;Acc:HGNC:8014]",{"v":162.493744,"d":"162.49"},{"v":8.032802,"d":"8.03"},{"v":20.2287749654479,"d":"20.23"},{"v":4.33833704924789,"d":"4.34"},{"v":4.77315893235335E-9,"d":"0.00"},{"v":8.28407123270896e-07,"d":"0.00"},"up","yes"]
[163270,0,"chr6","-",24804285,24910967,"ENST00000259698",23,5471,"MSTRG.12716","RIPOR2","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0007155(cell adhesion);GO:0007605(sensory perception of sound);GO:0048741(skeletal muscle fiber development);GO:0005886(plasma membrane);GO:0005856(cytoskeleton);GO:0042995(cell projection);GO:0005515(protein binding);GO:0007275(multicellular organism development);GO:0030154(cell differentiation);GO:0006935(chemotaxis);GO:2000114(regulation of establishment of cell polarity);GO:0030175(filopodium);GO:0032420(stereocilium);GO:0007517(muscle organ development);GO:0060171(stereocilium membrane);GO:0016324(apical plasma membrane);GO:0051491(positive regulation of filopodium assembly);GO:0007162(negative regulation of cell adhesion);GO:0009968(negative regulation of signal transduction);GO:1901741(positive regulation of myoblast fusion);GO:0071889(14-3-3 protein binding);GO:2000405(negative regulation of T cell migration);GO:0090023(positive regulation of neutrophil chemotaxis);GO:0045663(positive regulation of myoblast differentiation);GO:1990869(cellular response to chemokine);GO:0035024(negative regulation of Rho protein signal transduction);GO:1903904(negative regulation of establishment of T cell polarity);GO:1905872(negative regulation of protein localization to cell leading edge);GO:2000391(positive regulation of neutrophil extravasation);GO:2001107(negative regulation of Rho guanyl-nucleotide exchange factor activity)","NA","NA","NA","RHO family interacting cell polarization regulator 2 [Source:HGNC Symbol;Acc:HGNC:13872]",{"v":0.275192,"d":"0.28"},{"v":6.307693,"d":"6.31"},{"v":0.0436279952115615,"d":"0.04"},{"v":-4.51860200908783,"d":"-4.52"},{"v":4.81246125297596e-09,"d":"0.00"},{"v":8.28407123270896e-07,"d":"0.00"},"down","yes"]
[165226,0,"chr6","-",33291654,33299324,"ENST00000497454",18,3278,"MSTRG.12950","RGL2","GO:0005622(intracellular);GO:0007264(small GTPase mediated signal transduction);GO:0007165(signal transduction);GO:0043547(positive regulation of GTPase activity);GO:0005515(protein binding);GO:0005085(guanyl-nucleotide exchange factor activity);GO:0005089(Rho guanyl-nucleotide exchange factor activity);GO:0010667(negative regulation of cardiac muscle cell apoptotic process);GO:0014068(positive regulation of phosphatidylinositol 3-kinase signaling);GO:0032485(regulation of Ral protein signal transduction);GO:0005575(cellular_component);GO:0007265(Ras protein signal transduction);GO:0005088(Ras guanyl-nucleotide exchange factor activity)","04014(Ras signaling pathway)","K17636","NA","ral guanine nucleotide dissociation stimulator like 2 [Source:HGNC Symbol;Acc:HGNC:9769]",{"v":0.603315,"d":"0.60"},{"v":13.526538,"d":"13.53"},{"v":0.0446023217470723,"d":"0.04"},{"v":-4.48673737905054,"d":"-4.49"},{"v":5.09191535500352e-09,"d":"0.00"},{"v":8.69020220587268e-07,"d":"0.00"},"down","yes"]
[199648,0,"chrX","-",119786506,119791595,"ENST00000468844",2,1915,"MSTRG.15420","RPL39","GO:0003723(RNA binding);GO:0006412(translation);GO:0030529(intracellular ribonucleoprotein complex);GO:0005622(intracellular);GO:0003735(structural constituent of ribosome);GO:0005840(ribosome);GO:0005615(extracellular space);GO:0005829(cytosol);GO:0002227(innate immune response in mucosa);GO:0019731(antibacterial humoral response);GO:0050830(defense response to Gram-positive bacterium);GO:0061844(antimicrobial humoral immune response mediated by antimicrobial peptide);GO:0006413(translational initiation);GO:0006364(rRNA processing);GO:0000184(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay);GO:0019083(viral transcription);GO:0006614(SRP-dependent cotranslational protein targeting to membrane);GO:0022625(cytosolic large ribosomal subunit)","03010(Ribosome)","NA","NA","ribosomal protein L39 [Source:HGNC Symbol;Acc:HGNC:10350]",{"v":0.329829,"d":"0.33"},{"v":7.899072,"d":"7.90"},{"v":0.0417554112685642,"d":"0.04"},{"v":-4.58189301483615,"d":"-4.58"},{"v":5.41612229558044e-09,"d":"0.00"},{"v":9.16518050831782e-07,"d":"0.00"},"down","yes"]
[183956,0,"chr8","-",56067295,56074509,"ENST00000519807",6,1826,"MSTRG.14365","RPS20","GO:0003723(RNA binding);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0006412(translation);GO:0030529(intracellular ribonucleoprotein complex);GO:0005622(intracellular);GO:0003735(structural constituent of ribosome);GO:0005840(ribosome);GO:0015935(small ribosomal subunit);GO:0005515(protein binding);GO:0022627(cytosolic small ribosomal subunit);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0031012(extracellular matrix);GO:0002181(cytoplasmic translation);GO:0006413(translational initiation);GO:0006364(rRNA processing);GO:0000184(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay);GO:0019083(viral transcription);GO:0006614(SRP-dependent cotranslational protein targeting to membrane)","03010(Ribosome)","K02969","NA","ribosomal protein S20 [Source:HGNC Symbol;Acc:HGNC:10405]",{"v":42.983387,"d":"42.98"},{"v":2.13083,"d":"2.13"},{"v":20.1721333940296,"d":"20.17"},{"v":4.33429176556237,"d":"4.33"},{"v":5.7190326174788e-09,"d":"0.00"},{"v":9.596440613934171E-7,"d":"0.00"},"up","yes"]
[124256,0,"chr20","+",45891341,45898820,"ENST00000191018",15,1898,"MSTRG.9785","CTSA","GO:0016787(hydrolase activity);GO:0008233(peptidase activity);GO:0006508(proteolysis);GO:0004180(carboxypeptidase activity);GO:0004185(serine-type carboxypeptidase activity);GO:0043231(intracellular membrane-bounded organelle);GO:0005654(nucleoplasm);GO:0005765(lysosomal membrane);GO:0016020(membrane);GO:0043085(positive regulation of catalytic activity);GO:0005764(lysosome);GO:0005576(extracellular region);GO:0006687(glycosphingolipid metabolic process);GO:0070062(extracellular exosome);GO:0043312(neutrophil degranulation);GO:0005783(endoplasmic reticulum);GO:0006886(intracellular protein transport);GO:0043202(lysosomal lumen);GO:0035578(azurophil granule lumen);GO:0008047(enzyme activator activity);GO:0031647(regulation of protein stability);GO:0051603(proteolysis involved in cellular protein catabolic process);GO:1904715(negative regulation of chaperone-mediated autophagy);GO:0098575(lumenal side of lysosomal membrane);GO:0004308(exo-alpha-sialidase activity);GO:1904714(regulation of chaperone-mediated autophagy)","04142(Lysosome);04614(Renin-angiotensin system)","K13289","EC:3.4.16.5","cathepsin A [Source:HGNC Symbol;Acc:HGNC:9251]",{"v":2.056009,"d":"2.06"},{"v":44.673141,"d":"44.67"},{"v":0.0460233812527308,"d":"0.05"},{"v":-4.44148921018167,"d":"-4.44"},{"v":5.83135297449319e-09,"d":"0.00"},{"v":9.70337134955666e-07,"d":"0.00"},"down","yes"]
[66012,"j","chr15","+",85544053,85749358,"MSTRG.5391.9",34,12618,"MSTRG.5391","AKAP13","NA","NA","NA","NA","NA",{"v":0.131559,"d":"0.13"},{"v":2.933315,"d":"2.93"},{"v":0.0448499394030304,"d":"0.04"},{"v":-4.47875015386111,"d":"-4.48"},{"v":5.9398306217106e-09,"d":"0.00"},{"v":9.72502577328138e-07,"d":"0.00"},"down","yes"]
[56844,0,"chr14","+",74781385,74836190,"ENST00000549293",17,5500,"MSTRG.4525","YLPM1","GO:0005634(nucleus);GO:0003723(RNA binding);GO:0016607(nuclear speck);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0005515(protein binding);GO:0008150(biological_process)","NA","NA","NA","YLP motif containing 1 [Source:HGNC Symbol;Acc:HGNC:17798]",{"v":3.593152,"d":"3.59"},{"v":0.171793,"d":"0.17"},{"v":20.9155902743418,"d":"20.92"},{"v":4.38650680880758,"d":"4.39"},{"v":5.94177255779411E-9,"d":"0.00"},{"v":9.72502577328138e-07,"d":"0.00"},"up","yes"]
[24356,0,"chr10","+",128047570,128085855,"ENST00000306042",18,4957,"MSTRG.2045","PTPRE","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016787(hydrolase activity);GO:0004725(protein tyrosine phosphatase activity);GO:0016791(phosphatase activity);GO:0006470(protein dephosphorylation);GO:0016311(dephosphorylation);GO:0035335(peptidyl-tyrosine dephosphorylation);GO:0005886(plasma membrane);GO:0004721(phosphoprotein phosphatase activity);GO:0005515(protein binding);GO:0046627(negative regulation of insulin receptor signaling pathway);GO:0005001(transmembrane receptor protein tyrosine phosphatase activity)","NA","NA","NA","protein tyrosine phosphatase, receptor type E [Source:HGNC Symbol;Acc:HGNC:9669]",{"v":0.529891,"d":"0.53"},{"v":11.56029,"d":"11.56"},{"v":0.0458371719048571,"d":"0.05"},{"v":-4.44733815538111,"d":"-4.45"},{"v":6.14969480637797e-09,"d":"0.00"},{"v":9.98350454420775e-07,"d":"0.00"},"down","yes"]
[46292,0,"chr12","-",108622829,108632078,"ENST00000228463",2,1704,"MSTRG.3684","SELPLG","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0007155(cell adhesion);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0050900(leukocyte migration);GO:0046718(viral entry into host cell);GO:0016032(viral process);GO:0005887(integral component of plasma membrane);GO:0005102(receptor binding);GO:0001931(uropod);GO:0001618(virus receptor activity);GO:0050901(leukocyte tethering or rolling);GO:0044853(plasma membrane raft);GO:0050902(leukocyte adhesive activation);GO:0071354(cellular response to interleukin-6)","04514(Cell adhesion molecules (CAMs));05150(Staphylococcus aureus infection)","K06544","NA","selectin P ligand [Source:HGNC Symbol;Acc:HGNC:10722]",{"v":22.972256,"d":"22.97"},{"v":1.140857,"d":"1.14"},{"v":20.1359644547914,"d":"20.14"},{"v":4.33170266976958,"d":"4.33"},{"v":6.76974924172481e-09,"d":"0.00"},{"v":1.09014800692549E-6,"d":"0.00"},"up","yes"]
[192487,0,"chr9","+",107283279,107332194,"ENST00000358015",10,4119,"MSTRG.14892","RAD23B","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0003684(damaged DNA binding);GO:0005515(protein binding);GO:0006281(DNA repair);GO:0006974(cellular response to DNA damage stimulus);GO:0000502(proteasome complex);GO:0006289(nucleotide-excision repair);GO:0043161(proteasome-mediated ubiquitin-dependent protein catabolic process);GO:0016579(protein deubiquitination);GO:0006457(protein folding);GO:0070911(global genome nucleotide-excision repair);GO:0000715(nucleotide-excision repair, DNA damage recognition);GO:0000717(nucleotide-excision repair, DNA duplex unwinding);GO:0006294(nucleotide-excision repair, preincision complex assembly);GO:0032434(regulation of proteasomal ubiquitin-dependent protein catabolic process);GO:0003697(single-stranded DNA binding);GO:0071942(XPC complex);GO:0031593(polyubiquitin binding);GO:0007283(spermatogenesis);GO:0048568(embryonic organ development)","04141(Protein processing in endoplasmic reticulum);03420(Nucleotide excision repair)","K10839","NA","RAD23 homolog B, nucleotide excision repair protein [Source:HGNC Symbol;Acc:HGNC:9813]",{"v":5.634344,"d":"5.63"},{"v":0.274265,"d":"0.27"},{"v":20.5434306236669,"d":"20.54"},{"v":4.36060521765709,"d":"4.36"},{"v":7.08840103605964e-09,"d":"0.00"},{"v":1.12532995511449E-6,"d":"0.00"},"up","yes"]
[53072,0,"chr14","-",22946229,22957142,"ENST00000541587",10,1637,"MSTRG.4270","HAUS4","GO:0005737(cytoplasm);GO:0051301(cell division);GO:0005856(cytoskeleton);GO:0007049(cell cycle);GO:0005874(microtubule);GO:0007098(centrosome cycle);GO:0051225(spindle assembly);GO:0070652(HAUS complex);GO:0005813(centrosome);GO:0005815(microtubule organizing center);GO:0005819(spindle);GO:0003674(molecular_function);GO:0005829(cytosol);GO:0000086(G2/M transition of mitotic cell cycle);GO:0010389(regulation of G2/M transition of mitotic cell cycle);GO:0097711(ciliary basal body docking)","NA","NA","NA","HAUS augmin like complex subunit 4 [Source:HGNC Symbol;Acc:HGNC:20163]",{"v":0.434386,"d":"0.43"},{"v":10.036304,"d":"10.04"},{"v":0.0432814709478709,"d":"0.04"},{"v":-4.53010665888316,"d":"-4.53"},{"v":7.10094022157583e-09,"d":"0.00"},{"v":1.12532995511449E-6,"d":"0.00"},"down","yes"]
[170562,0,"chr6","-",159679064,159693234,"ENST00000367055",6,990,"MSTRG.13403","SOD2","GO:0046872(metal ion binding);GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0004784(superoxide dismutase activity);GO:0006801(superoxide metabolic process);GO:0003677(DNA binding);GO:0019825(oxygen binding);GO:0019899(enzyme binding);GO:0030145(manganese ion binding);GO:0042802(identical protein binding);GO:0000302(response to reactive oxygen species);GO:0000303(response to superoxide);GO:0001306(age-dependent response to oxidative stress);GO:0001666(response to hypoxia);GO:0001836(release of cytochrome c from mitochondria);GO:0001889(liver development);GO:0003032(detection of oxygen);GO:0003069(acetylcholine-mediated vasodilation involved in regulation of systemic arterial blood pressure);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0006749(glutathione metabolic process);GO:0006979(response to oxidative stress);GO:0007005(mitochondrion organization);GO:0007507(heart development);GO:0007568(aging);GO:0007626(locomotory behavior);GO:0008217(regulation of blood pressure);GO:0008630(intrinsic apoptotic signaling pathway in response to DNA damage);GO:0008631(intrinsic apoptotic signaling pathway in response to oxidative stress);GO:0008637(apoptotic mitochondrial changes);GO:0009314(response to radiation);GO:0009409(response to cold);GO:0009791(post-embryonic development);GO:0010042(response to manganese ion);GO:0010043(response to zinc ion);GO:0010269(response to selenium ion);GO:0010332(response to gamma radiation);GO:0014823(response to activity);GO:0019430(removal of superoxide radicals);GO:0022904(respiratory electron transport chain);GO:0030097(hemopoiesis);GO:0031667(response to nutrient levels);GO:0032496(response to lipopolysaccharide);GO:0033591(response to L-ascorbic acid);GO:0034021(response to silicon dioxide);GO:0035900(response to isolation stress);GO:0035902(response to immobilization stress);GO:0042311(vasodilation);GO:0042493(response to drug);GO:0042542(response to hydrogen peroxide);GO:0042554(superoxide anion generation);GO:0042743(hydrogen peroxide metabolic process);GO:0043066(negative regulation of apoptotic process);GO:0045429(positive regulation of nitric oxide biosynthetic process);GO:0045599(negative regulation of fat cell differentiation);GO:0046686(response to cadmium ion);GO:0048147(negative regulation of fibroblast proliferation);GO:0048666(neuron development);GO:0048678(response to axon injury);GO:0048773(erythrophore differentiation);GO:0050665(hydrogen peroxide biosynthetic process);GO:0050790(regulation of catalytic activity);GO:0051260(protein homooligomerization);GO:0051602(response to electrical stimulus);GO:0051881(regulation of mitochondrial membrane potential);GO:0055072(iron ion homeostasis);GO:0055093(response to hyperoxia);GO:0071000(response to magnetism);GO:0071361(cellular response to ethanol);GO:0005737(cytoplasm);GO:0005739(mitochondrion);GO:0005743(mitochondrial inner membrane);GO:0042645(mitochondrial nucleoid);GO:0043209(myelin sheath);GO:0008285(negative regulation of cell proliferation);GO:0030335(positive regulation of cell migration);GO:0005759(mitochondrial matrix);GO:0070062(extracellular exosome);GO:0035722(interleukin-12-mediated signaling pathway);GO:0051289(protein homotetramerization);GO:0034599(cellular response to oxidative stress);GO:0043524(negative regulation of neuron apoptotic process);GO:1902176(negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway);GO:0001315(age-dependent response to reactive oxygen species);GO:0032364(oxygen homeostasis)","04068(FoxO signaling pathway);04146(Peroxisome);04211(Longevity regulating pathway - mammal);04213(Longevity regulating pathway - multiple species);05016(Huntington's disease)","K04564","EC:1.15.1.1","superoxide dismutase 2 [Source:HGNC Symbol;Acc:HGNC:11180]",{"v":52.249504,"d":"52.25"},{"v":2.644541,"d":"2.64"},{"v":19.7574944007297,"d":"19.76"},{"v":4.30432809419642,"d":"4.30"},{"v":7.228153161994e-09,"d":"0.00"},{"v":1.13647056959603e-06,"d":"0.00"},"up","yes"]
[36321,"j","chr11","-",123057492,123063198,"MSTRG.2940.6",9,3040,"MSTRG.2940","HSPA8","NA","NA","NA","NA","NA",{"v":27.123129,"d":"27.12"},{"v":1.394942,"d":"1.39"},{"v":19.4439116465057,"d":"19.44"},{"v":4.28124657850843,"d":"4.28"},{"v":7.61251388169946e-09,"d":"0.00"},{"v":1.18755216554512E-6,"d":"0.00"},"up","yes"]
[88534,0,"chr17","-",76734147,76736555,"ENST00000582449",3,1518,"MSTRG.7260","SRSF2","GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0006397(mRNA processing);GO:0008380(RNA splicing);GO:0005634(nucleus);GO:0016607(nuclear speck);GO:0005829(cytosol);GO:0005515(protein binding);GO:0005080(protein kinase C binding);GO:0036002(pre-mRNA binding);GO:0000278(mitotic cell cycle);GO:0000381(regulation of alternative mRNA splicing, via spliceosome);GO:0033197(response to vitamin E);GO:0043484(regulation of RNA splicing);GO:0005681(spliceosomal complex);GO:0035061(interchromatin granule);GO:0005654(nucleoplasm);GO:1903507(negative regulation of nucleic acid-templated transcription);GO:0003714(transcription corepressor activity);GO:0070062(extracellular exosome);GO:0006369(termination of RNA polymerase II transcription);GO:0006405(RNA export from nucleus);GO:0031124(mRNA 3'-end processing);GO:0000398(mRNA splicing, via spliceosome);GO:0006406(mRNA export from nucleus)","03040(Spliceosome);05168(Herpes simplex infection)","NA","NA","serine and arginine rich splicing factor 2 [Source:HGNC Symbol;Acc:HGNC:10783]",{"v":9.217183,"d":"9.22"},{"v":0.439679,"d":"0.44"},{"v":20.9634369619654,"d":"20.96"},{"v":4.38980336145205,"d":"4.39"},{"v":7.73438933559438e-09,"d":"0.00"},{"v":1.19721152134224E-6,"d":"0.00"},"up","yes"]
[24717,"j","chr11","-",309055,311138,"MSTRG.2063.2",3,1382,"MSTRG.2063","AC136475.2","NA","NA","NA","NA","NA",{"v":0.518529,"d":"0.52"},{"v":11.743381,"d":"11.74"},{"v":0.0441550010171687,"d":"0.04"},{"v":-4.50127934229579,"d":"-4.50"},{"v":7.92752542281202e-09,"d":"0.00"},{"v":1.21252646423914E-6,"d":"0.00"},"down","yes"]
[143326,0,"chr3","-",183919934,184018015,"ENST00000334444",30,5921,"ENSG00000114770","ABCC5","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0055085(transmembrane transport);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0042626(ATPase activity, coupled to transmembrane movement of substances);GO:0016887(ATPase activity);GO:0005886(plasma membrane);GO:0008514(organic anion transmembrane transporter activity);GO:0015711(organic anion transport);GO:0005887(integral component of plasma membrane);GO:0030213(hyaluronan biosynthetic process);GO:0043225(ATPase-coupled anion transmembrane transporter activity);GO:0099133(ATP hydrolysis coupled anion transmembrane transport)","02010(ABC transporters);01523(Antifolate resistance)","K05668","NA","ATP binding cassette subfamily C member 5 [Source:HGNC Symbol;Acc:HGNC:56]",{"v":2.475752,"d":"2.48"},{"v":0.118235,"d":"0.12"},{"v":20.9392481075824,"d":"20.94"},{"v":4.38813773338637,"d":"4.39"},{"v":7.95477598233809e-09,"d":"0.00"},{"v":1.21252646423914E-6,"d":"0.00"},"up","yes"]
[119415,0,"chr2","-",219249711,219254608,"ENST00000392088",4,2499,"MSTRG.9451","TUBA4A","GO:0005737(cytoplasm);GO:0005525(GTP binding);GO:0000166(nucleotide binding);GO:0003924(GTPase activity);GO:0015630(microtubule cytoskeleton);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0005200(structural constituent of cytoskeleton);GO:0007010(cytoskeleton organization);GO:0005874(microtubule);GO:0005576(extracellular region);GO:0007017(microtubule-based process);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0000086(G2/M transition of mitotic cell cycle);GO:0010389(regulation of G2/M transition of mitotic cell cycle);GO:0097711(ciliary basal body docking);GO:0002576(platelet degranulation);GO:0019899(enzyme binding)","04145(Phagosome);04210(Apoptosis);04530(Tight junction);04540(Gap junction);05130(Pathogenic Escherichia coli infection)","K07374","NA","tubulin alpha 4a [Source:HGNC Symbol;Acc:HGNC:12407]",{"v":0.357868,"d":"0.36"},{"v":7.910264,"d":"7.91"},{"v":0.0452409679373533,"d":"0.05"},{"v":-4.46622639343813,"d":"-4.47"},{"v":8.44550511182482e-09,"d":"0.00"},{"v":1.2775745914615e-06,"d":"0.00"},"down","yes"]
[157384,"j","chr5","+",112707521,112844904,"MSTRG.12254.2",16,9690,"MSTRG.12254","APC","NA","NA","NA","NA","NA",{"v":2.345597,"d":"2.35"},{"v":0.116662,"d":"0.12"},{"v":20.1059213797123,"d":"20.11"},{"v":4.32954854589674,"d":"4.33"},{"v":8.55760960916797e-09,"d":"0.00"},{"v":1.28479961410426e-06,"d":"0.00"},"up","yes"]
[82719,0,"chr17","-",38850114,38853737,"ENST00000577407",4,615,"MSTRG.6767","RPL23","GO:0003723(RNA binding);GO:0016020(membrane);GO:0006412(translation);GO:0030529(intracellular ribonucleoprotein complex);GO:0003735(structural constituent of ribosome);GO:0005840(ribosome);GO:0005515(protein binding);GO:0005925(focal adhesion);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0031012(extracellular matrix);GO:0043234(protein complex);GO:0006413(translational initiation);GO:0006610(ribosomal protein import into nucleus);GO:0006364(rRNA processing);GO:0005737(cytoplasm);GO:0000184(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay);GO:0019083(viral transcription);GO:0006614(SRP-dependent cotranslational protein targeting to membrane);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0008284(positive regulation of cell proliferation);GO:0010628(positive regulation of gene expression);GO:0032986(protein-DNA complex disassembly);GO:0050821(protein stabilization);GO:0005654(nucleoplasm);GO:0071158(positive regulation of cell cycle arrest);GO:0072717(cellular response to actinomycin D);GO:0022625(cytosolic large ribosomal subunit);GO:0005730(nucleolus);GO:0031625(ubiquitin protein ligase binding);GO:0001223(transcription coactivator binding);GO:1990948(ubiquitin ligase inhibitor activity);GO:1904667(negative regulation of ubiquitin protein ligase activity);GO:2000059(negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process);GO:0070180(large ribosomal subunit rRNA binding);GO:0071157(negative regulation of cell cycle arrest);GO:1901798(positive regulation of signal transduction by p53 class mediator)","03010(Ribosome)","NA","NA","ribosomal protein L23 [Source:HGNC Symbol;Acc:HGNC:10316]",{"v":35.669884,"d":"35.67"},{"v":1.792879,"d":"1.79"},{"v":19.895310280281,"d":"19.90"},{"v":4.31435649386031,"d":"4.31"},{"v":8.85189221735824e-09,"d":"0.00"},{"v":1.31906405818067e-06,"d":"0.00"},"up","yes"]
[167262,0,"chr6","-",73517521,73521721,"ENST00000331523",8,1923,"MSTRG.13126","EEF1A1","GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0006412(translation);GO:0005525(GTP binding);GO:0000166(nucleotide binding);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003924(GTPase activity);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0005615(extracellular space);GO:0003746(translation elongation factor activity);GO:0006414(translational elongation);GO:0000049(tRNA binding);GO:0005730(nucleolus);GO:0005576(extracellular region);GO:0070062(extracellular exosome);GO:0019901(protein kinase binding);GO:0032587(ruffle membrane);GO:0043312(neutrophil degranulation);GO:0034774(secretory granule lumen);GO:1904813(ficolin-1-rich granule lumen);GO:0030864(cortical actin cytoskeleton);GO:0071364(cellular response to epidermal growth factor stimulus);GO:0006479(protein methylation);GO:1904714(regulation of chaperone-mediated autophagy);GO:0005853(eukaryotic translation elongation factor 1 complex);GO:0043209(myelin sheath);GO:0098574(cytoplasmic side of lysosomal membrane)","03013(RNA transport);05134(Legionellosis)","K03231","NA","eukaryotic translation elongation factor 1 alpha 1 [Source:HGNC Symbol;Acc:HGNC:3189]",{"v":45.042168,"d":"45.04"},{"v":919.505432,"d":"919.51"},{"v":0.0489852114326607,"d":"0.05"},{"v":-4.35150992244486,"d":"-4.35"},{"v":8.92026434104998e-09,"d":"0.00"},{"v":1.31940621008953E-6,"d":"0.00"},"down","yes"]
[1681,0,"chr1","+",12167003,12209228,"ENST00000492361",9,3583,"MSTRG.168","TNFRSF1B","GO:0071222(cellular response to lipopolysaccharide);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0006915(apoptotic process);GO:0006954(inflammatory response);GO:0006955(immune response);GO:0005887(integral component of plasma membrane);GO:0097190(apoptotic signaling pathway);GO:0033209(tumor necrosis factor-mediated signaling pathway);GO:0031625(ubiquitin protein ligase binding);GO:0043312(neutrophil degranulation);GO:0035579(specific granule membrane);GO:0005031(tumor necrosis factor-activated receptor activity);GO:0007275(multicellular organism development);GO:0042127(regulation of cell proliferation);GO:0043154(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process);GO:0051044(positive regulation of membrane protein ectodomain proteolysis);GO:0045121(membrane raft);GO:0007166(cell surface receptor signaling pathway);GO:0007568(aging);GO:0008630(intrinsic apoptotic signaling pathway in response to DNA damage);GO:0032496(response to lipopolysaccharide);GO:0050728(negative regulation of inflammatory response);GO:0050779(RNA destabilization);GO:0071363(cellular response to growth factor stimulus);GO:0097191(extrinsic apoptotic signaling pathway);GO:0005634(nucleus);GO:0030424(axon);GO:0043025(neuronal cell body);GO:0043196(varicosity);GO:0048471(perinuclear region of cytoplasm)","04668(TNF signaling pathway);04060(Cytokine-cytokine receptor interaction);04920(Adipocytokine signaling pathway);05014(Amyotrophic lateral sclerosis (ALS))","NA","NA","TNF receptor superfamily member 1B [Source:HGNC Symbol;Acc:HGNC:11917]",{"v":0.79022,"d":"0.79"},{"v":16.453791,"d":"16.45"},{"v":0.0480266219499202,"d":"0.05"},{"v":-4.38002185251915,"d":"-4.38"},{"v":9.52797463223818e-09,"d":"0.00"},{"v":1.39893086365097e-06,"d":"0.00"},"down","yes"]
[84119,"j","chr17","-",44205121,44220899,"MSTRG.6894.3",21,4643,"MSTRG.6894","UBTF","NA","NA","NA","NA","NA",{"v":3.21537,"d":"3.22"},{"v":0.159346,"d":"0.16"},{"v":20.178542291617,"d":"20.18"},{"v":4.33475005205634,"d":"4.33"},{"v":1.03250224624889E-8,"d":"0.00"},{"v":1.49882318330898e-06,"d":"0.00"},"up","yes"]
[125095,0,"chr20","+",59123381,59259113,"ENST00000637017",8,10953,"ENSG00000124203","ZNF831","GO:0003676(nucleic acid binding);GO:0046872(metal ion binding);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0005634(nucleus);GO:0007165(signal transduction);GO:0007275(multicellular organism development);GO:0043565(sequence-specific DNA binding);GO:0044212(transcription regulatory region DNA binding);GO:0001206(transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding);GO:0006366(transcription from RNA polymerase II promoter)","NA","NA","NA","zinc finger protein 831 [Source:HGNC Symbol;Acc:HGNC:16167]",{"v":1.529307,"d":"1.53"},{"v":0.076147,"d":"0.08"},{"v":20.083614587574,"d":"20.08"},{"v":4.32794703938883,"d":"4.33"},{"v":1.03584534904166E-8,"d":"0.00"},{"v":1.49882318330898e-06,"d":"0.00"},"up","yes"]
[43371,"j","chr12","-",57253777,57430807,"MSTRG.3484.15",23,4066,"MSTRG.3484","R3HDM2","NA","NA","NA","NA","NA",{"v":0.301204,"d":"0.30"},{"v":6.386139,"d":"6.39"},{"v":0.047165274667526,"d":"0.05"},{"v":-4.40613112049959,"d":"-4.41"},{"v":1.05277921333738E-8,"d":"0.00"},{"v":1.51236657064178e-06,"d":"0.00"},"down","yes"]
[114950,0,"chr2","-",144389213,144520119,"ENST00000539609",9,4061,"MSTRG.9162","ZEB2","GO:0003676(nucleic acid binding);GO:0003677(DNA binding);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0005730(nucleolus);GO:0005829(cytosol);GO:0006366(transcription from RNA polymerase II promoter);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0005515(protein binding);GO:0007399(nervous system development);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0019208(phosphatase regulator activity);GO:0001227(transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding);GO:0001205(transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding);GO:0070412(R-SMAD binding);GO:0001755(neural crest cell migration);GO:0001756(somitogenesis);GO:0001843(neural tube closure);GO:0007417(central nervous system development);GO:0021540(corpus callosum morphogenesis);GO:0021766(hippocampus development);GO:0021846(cell proliferation in forebrain);GO:0021957(corticospinal tract morphogenesis);GO:0030177(positive regulation of Wnt signaling pathway);GO:0043507(positive regulation of JUN kinase activity);GO:0045636(positive regulation of melanocyte differentiation);GO:0048023(positive regulation of melanin biosynthetic process);GO:0048066(developmental pigmentation);GO:0048598(embryonic morphogenesis);GO:0048668(collateral sprouting);GO:0050772(positive regulation of axonogenesis);GO:0061373(mammillary axonal complex development);GO:0097324(melanocyte migration);GO:1902748(positive regulation of lens fiber cell differentiation);GO:1903056(regulation of melanosome organization)","05206(MicroRNAs in cancer)","K09299","NA","zinc finger E-box binding homeobox 2 [Source:HGNC Symbol;Acc:HGNC:14881]",{"v":3.968284,"d":"3.97"},{"v":0.200838,"d":"0.20"},{"v":19.7586313347076,"d":"19.76"},{"v":4.30441111088805,"d":"4.30"},{"v":1.13971918914216E-8,"d":"0.00"},{"v":1.62556519777076E-6,"d":"0.00"},"up","yes"]
[53288,0,"chr14","-",23559565,23568070,"ENST00000308724",21,3298,"MSTRG.4277","AP1G2","GO:0006810(transport);GO:0016020(membrane);GO:0008565(protein transporter activity);GO:0006886(intracellular protein transport);GO:0015031(protein transport);GO:0016192(vesicle-mediated transport);GO:0030117(membrane coat);GO:0005794(Golgi apparatus);GO:0030131(clathrin adaptor complex);GO:0005515(protein binding);GO:0000139(Golgi membrane);GO:0030659(cytoplasmic vesicle membrane);GO:0031410(cytoplasmic vesicle);GO:0005768(endosome);GO:0010008(endosome membrane);GO:0016032(viral process);GO:0030133(transport vesicle);GO:0005798(Golgi-associated vesicle);GO:0030121(AP-1 adaptor complex)","04142(Lysosome)","NA","NA","adaptor related protein complex 1 gamma 2 subunit [Source:HGNC Symbol;Acc:HGNC:556]",{"v":4.335668,"d":"4.34"},{"v":0.216179,"d":"0.22"},{"v":20.055916624649,"d":"20.06"},{"v":4.32595599869202,"d":"4.33"},{"v":1.14966891841027e-08,"d":"0.00"},{"v":1.62812687679547E-6,"d":"0.00"},"up","yes"]
[11441,"j","chr1","-",154582067,154608198,"MSTRG.1019.5",15,6534,"MSTRG.1019","ADAR","NA","NA","NA","NA","NA",{"v":0.444682,"d":"0.44"},{"v":9.041569,"d":"9.04"},{"v":0.0491819506105633,"d":"0.05"},{"v":-4.34572723482488,"d":"-4.35"},{"v":1.16474682340221e-08,"d":"0.00"},{"v":1.63786370209122E-6,"d":"0.00"},"down","yes"]
[13001,0,"chr1","-",161623990,161631206,"ENST00000531221",5,1339,"MSTRG.1160","FCGR3B","GO:0016020(membrane);GO:0005886(plasma membrane);GO:0005576(extracellular region);GO:0031225(anchored component of membrane);GO:0070062(extracellular exosome);GO:0006501(C-terminal protein lipidation);GO:0043312(neutrophil degranulation);GO:0006955(immune response);GO:0030667(secretory granule membrane);GO:0019864(IgG binding);GO:0016021(integral component of membrane)","04145(Phagosome);04650(Natural killer cell mediated cytotoxicity);04380(Osteoclast differentiation);05322(Systemic lupus erythematosus);05150(Staphylococcus aureus infection);05152(Tuberculosis);05140(Leishmaniasis)","NA","NA","Fc fragment of IgG receptor IIIb [Source:HGNC Symbol;Acc:HGNC:3620]",{"v":19.464022,"d":"19.46"},{"v":384.997711,"d":"385.00"},{"v":0.0505562018783016,"d":"0.05"},{"v":-4.30596810713715,"d":"-4.31"},{"v":1.20183085558664E-8,"d":"0.00"},{"v":1.67819290380097e-06,"d":"0.00"},"down","yes"]
[167256,0,"chr6","-",73515750,73521018,"ENST00000316292",7,4441,"MSTRG.13126","EEF1A1","GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0006412(translation);GO:0005525(GTP binding);GO:0000166(nucleotide binding);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003924(GTPase activity);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0005615(extracellular space);GO:0003746(translation elongation factor activity);GO:0006414(translational elongation);GO:0000049(tRNA binding);GO:0005730(nucleolus);GO:0005576(extracellular region);GO:0070062(extracellular exosome);GO:0019901(protein kinase binding);GO:0032587(ruffle membrane);GO:0043312(neutrophil degranulation);GO:0034774(secretory granule lumen);GO:1904813(ficolin-1-rich granule lumen);GO:0030864(cortical actin cytoskeleton);GO:0071364(cellular response to epidermal growth factor stimulus);GO:0006479(protein methylation);GO:1904714(regulation of chaperone-mediated autophagy);GO:0005853(eukaryotic translation elongation factor 1 complex);GO:0043209(myelin sheath);GO:0098574(cytoplasmic side of lysosomal membrane)","03013(RNA transport);05134(Legionellosis)","NA","NA","eukaryotic translation elongation factor 1 alpha 1 [Source:HGNC Symbol;Acc:HGNC:3189]",{"v":6.334732,"d":"6.33"},{"v":123.352112,"d":"123.35"},{"v":0.0513548726267451,"d":"0.05"},{"v":-4.28335502168431,"d":"-4.28"},{"v":1.38362817451206e-08,"d":"0.00"},{"v":1.91863106865672e-06,"d":"0.00"},"down","yes"]
[115650,0,"chr2","-",159768630,159798255,"ENST00000553424",5,3866,"MSTRG.9190","CD302","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0030246(carbohydrate binding);GO:0042995(cell projection);GO:0007165(signal transduction);GO:0004888(transmembrane signaling receptor activity);GO:0005887(integral component of plasma membrane);GO:0030175(filopodium);GO:0005938(cell cortex);GO:0005902(microvillus);GO:0006909(phagocytosis)","NA","NA","NA","CD302 molecule [Source:HGNC Symbol;Acc:HGNC:30843]",{"v":0.206931,"d":"0.21"},{"v":4.339597,"d":"4.34"},{"v":0.0476843817524991,"d":"0.05"},{"v":-4.39033937758734,"d":"-4.39"},{"v":1.46501635606042E-8,"d":"0.00"},{"v":2.01747907571135e-06,"d":"0.00"},"down","yes"]
[41219,"j","chr12","+",49208453,49273334,"MSTRG.3350.2",5,2027,"MSTRG.3350","TUBA1C","NA","NA","NA","NA","NA",{"v":0.459054,"d":"0.46"},{"v":9.477782,"d":"9.48"},{"v":0.0484347498180481,"d":"0.05"},{"v":-4.36781370009287,"d":"-4.37"},{"v":1.52906651241946e-08,"d":"0.00"},{"v":2.09126028219122e-06,"d":"0.00"},"down","yes"]
[119943,"j","chr2","-",230176789,230218065,"MSTRG.9473.11",14,2428,"MSTRG.9473","SP110","NA","NA","NA","NA","NA",{"v":10.475586,"d":"10.48"},{"v":0.559492,"d":"0.56"},{"v":18.7233883594403,"d":"18.72"},{"v":4.22676963702087,"d":"4.23"},{"v":1.55245378840331E-8,"d":"0.00"},{"v":2.09569350147866e-06,"d":"0.00"},"up","yes"]
[2118,0,"chr1","-",16985958,17011772,"ENST00000326735",29,3840,"ENSG00000159363","ATP13A2","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0016787(hydrolase activity);GO:0005765(lysosomal membrane);GO:0005515(protein binding);GO:0006812(cation transport);GO:0099132(ATP hydrolysis coupled cation transmembrane transport);GO:0070588(calcium ion transmembrane transport);GO:0016887(ATPase activity);GO:0005764(lysosome);GO:0005887(integral component of plasma membrane);GO:0034220(ion transmembrane transport);GO:0005776(autophagosome);GO:1903146(regulation of mitophagy);GO:0080025(phosphatidylinositol-3,5-bisphosphate binding);GO:0043202(lysosomal lumen);GO:0043005(neuron projection);GO:0050714(positive regulation of protein secretion);GO:0031982(vesicle);GO:0016241(regulation of macroautophagy);GO:0034599(cellular response to oxidative stress);GO:1901215(negative regulation of neuron death);GO:0008270(zinc ion binding);GO:0010821(regulation of mitochondrion organization);GO:0055069(zinc ion homeostasis);GO:0071287(cellular response to manganese ion);GO:0043025(neuronal cell body);GO:0046777(protein autophosphorylation);GO:1905165(regulation of lysosomal protein catabolic process);GO:1904714(regulation of chaperone-mediated autophagy);GO:0005388(calcium-transporting ATPase activity);GO:0030133(transport vesicle);GO:0019829(cation-transporting ATPase activity);GO:1903135(cupric ion binding);GO:0030145(manganese ion binding);GO:0070300(phosphatidic acid binding);GO:0006874(cellular calcium ion homeostasis);GO:0006879(cellular iron ion homeostasis);GO:0006882(cellular zinc ion homeostasis);GO:0016243(regulation of autophagosome size);GO:0030003(cellular cation homeostasis);GO:0033157(regulation of intracellular protein transport);GO:0052548(regulation of endopeptidase activity);GO:0071294(cellular response to zinc ion);GO:1903543(positive regulation of exosomal secretion);GO:1905037(autophagosome organization);GO:1905122(polyamine import);GO:1905123(regulation of glucosylceramidase activity);GO:1905166(negative regulation of lysosomal protein catabolic process);GO:1990938(peptidyl-aspartic acid autophosphorylation);GO:0005770(late endosome);GO:0005771(multivesicular body);GO:0012506(vesicle membrane);GO:0032585(multivesicular body membrane);GO:1905103(integral component of lysosomal membrane)","NA","NA","NA","ATPase 13A2 [Source:HGNC Symbol;Acc:HGNC:30213]",{"v":4.514927,"d":"4.51"},{"v":0.235598,"d":"0.24"},{"v":19.1636898445657,"d":"19.16"},{"v":4.26030346430897,"d":"4.26"},{"v":1.55329846864404E-8,"d":"0.00"},{"v":2.09569350147866e-06,"d":"0.00"},"up","yes"]
[96495,0,"chr19","+",10625258,10644559,"ENST00000335757",22,3671,"MSTRG.7804","SLC44A2","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005765(lysosomal membrane);GO:0004871(signal transducer activity);GO:0007165(signal transduction);GO:0005886(plasma membrane);GO:0070062(extracellular exosome);GO:0055085(transmembrane transport);GO:0043312(neutrophil degranulation);GO:0035579(specific granule membrane);GO:0043123(positive regulation of I-kappaB kinase/NF-kappaB signaling);GO:0006656(phosphatidylcholine biosynthetic process);GO:0015220(choline transmembrane transporter activity);GO:0015871(choline transport)","05231(Choline metabolism in cancer)","K15377","NA","solute carrier family 44 member 2 [Source:HGNC Symbol;Acc:HGNC:17292]",{"v":1.654546,"d":"1.65"},{"v":32.025135,"d":"32.03"},{"v":0.051663982056594,"d":"0.05"},{"v":-4.2746973447722,"d":"-4.27"},{"v":1.58566151443624E-8,"d":"0.00"},{"v":2.1249992698163e-06,"d":"0.00"},"down","yes"]
[133902,"j","chr3","-",18347517,18445547,"MSTRG.10755.35",11,3999,"MSTRG.10755","SATB1","NA","NA","NA","NA","NA",{"v":7.421014,"d":"7.42"},{"v":0.404402,"d":"0.40"},{"v":18.3505867923502,"d":"18.35"},{"v":4.19775429140971,"d":"4.20"},{"v":1.62157417177739e-08,"d":"0.00"},{"v":2.15863953747006e-06,"d":"0.00"},"up","yes"]
[73049,"j","chr16","+",53450090,53491520,"MSTRG.5924.8",19,4199,"MSTRG.5924","RBL2","NA","NA","NA","NA","NA",{"v":0.938352,"d":"0.94"},{"v":18.210707,"d":"18.21"},{"v":0.0515274887460437,"d":"0.05"},{"v":-4.27851390704339,"d":"-4.28"},{"v":1.66239533290146e-08,"d":"0.00"},{"v":2.19832516605142e-06,"d":"0.00"},"down","yes"]
[158382,0,"chr5","+",134115625,134148229,"ENST00000395023",9,2815,"MSTRG.12319","TCF7","GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0008013(beta-catenin binding);GO:0060070(canonical Wnt signaling pathway);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0016604(nuclear body);GO:0016055(Wnt signaling pathway);GO:0005667(transcription factor complex);GO:0033153(T cell receptor V(D)J recombination);GO:0006955(immune response);GO:0044212(transcription regulatory region DNA binding);GO:1904837(beta-catenin-TCF complex assembly);GO:0043565(sequence-specific DNA binding);GO:0071353(cellular response to interleukin-4);GO:0001047(core promoter binding);GO:0001227(transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0021915(neural tube development);GO:0030538(embryonic genitalia morphogenesis);GO:0042127(regulation of cell proliferation);GO:0044336(canonical Wnt signaling pathway involved in negative regulation of apoptotic process);GO:0046632(alpha-beta T cell differentiation);GO:0048557(embryonic digestive tract morphogenesis);GO:0048619(embryonic hindgut morphogenesis);GO:0005719(nuclear euchromatin)","04310(Wnt signaling pathway);04390(Hippo signaling pathway);04520(Adherens junction);04916(Melanogenesis);05200(Pathways in cancer);05210(Colorectal cancer);05225(Hepatocellular carcinoma);05226(Gastric cancer);05216(Thyroid cancer);05221(Acute myeloid leukemia);05217(Basal cell carcinoma);05215(Prostate cancer);05213(Endometrial cancer);05224(Breast cancer);05412(Arrhythmogenic right ventricular cardiomyopathy (ARVC));05165(Human papillomavirus infection)","K02620","NA","transcription factor 7 [Source:HGNC Symbol;Acc:HGNC:11639]",{"v":0.457105,"d":"0.46"},{"v":9.190812,"d":"9.19"},{"v":0.0497349962114338,"d":"0.05"},{"v":-4.3295948230338,"d":"-4.33"},{"v":1.76194584567153e-08,"d":"0.00"},{"v":2.31464043726112e-06,"d":"0.00"},"down","yes"]
[59508,"j","chr14","-",105736375,105864264,"MSTRG.4749.20",7,2636,"MSTRG.4749","IGHG1","NA","NA","NA","NA","NA",{"v":0.558286,"d":"0.56"},{"v":11.076013,"d":"11.08"},{"v":0.0504049607020143,"d":"0.05"},{"v":-4.31029046343029,"d":"-4.31"},{"v":1.78882593076402E-8,"d":"0.00"},{"v":2.3345932147383E-6,"d":"0.00"},"down","yes"]
[30825,0,"chr11","-",64726911,64744834,"ENST00000377497",17,2221,"MSTRG.2519","RASGRP2","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0007264(small GTPase mediated signal transduction);GO:0046872(metal ion binding);GO:0035556(intracellular signal transduction);GO:0005509(calcium ion binding);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0042995(cell projection);GO:0007165(signal transduction);GO:0030054(cell junction);GO:0045202(synapse);GO:0005085(guanyl-nucleotide exchange factor activity);GO:0008289(lipid binding);GO:0007265(Ras protein signal transduction);GO:0043547(positive regulation of GTPase activity);GO:0032587(ruffle membrane);GO:0001558(regulation of cell growth);GO:0043005(neuron projection);GO:0071277(cellular response to calcium ion);GO:0019992(diacylglycerol binding);GO:0005622(intracellular)","04014(Ras signaling pathway);04015(Rap1 signaling pathway);04010(MAPK signaling pathway);04611(Platelet activation);04062(Chemokine signaling pathway);05200(Pathways in cancer)","K12361","NA","RAS guanyl releasing protein 2 [Source:HGNC Symbol;Acc:HGNC:9879]",{"v":1.286355,"d":"1.29"},{"v":24.877203,"d":"24.88"},{"v":0.0517081843967748,"d":"0.05"},{"v":-4.27346354068258,"d":"-4.27"},{"v":1.84466071830218E-8,"d":"0.00"},{"v":2.39183020928947E-6,"d":"0.00"},"down","yes"]
[37872,0,"chr12","+",6534534,6538359,"ENST00000396861",9,1348,"MSTRG.3056","GAPDH","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0043231(intracellular membrane-bounded organelle);GO:0005829(cytosol);GO:0016740(transferase activity);GO:0016491(oxidoreductase activity);GO:0050661(NADP binding);GO:0055114(oxidation-reduction process);GO:0031965(nuclear membrane);GO:0006096(glycolytic process);GO:0030529(intracellular ribonucleoprotein complex);GO:0005886(plasma membrane);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0051287(NAD binding);GO:0006915(apoptotic process);GO:0048471(perinuclear region of cytoplasm);GO:0008017(microtubule binding);GO:0042802(identical protein binding);GO:0004365(glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity);GO:0016620(oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor);GO:0006006(glucose metabolic process);GO:0015630(microtubule cytoskeleton);GO:0070062(extracellular exosome);GO:0050821(protein stabilization);GO:0006417(regulation of translation);GO:0071346(cellular response to interferon-gamma);GO:0031012(extracellular matrix);GO:0061844(antimicrobial humoral immune response mediated by antimicrobial peptide);GO:0017148(negative regulation of translation);GO:0031982(vesicle);GO:0000226(microtubule cytoskeleton organization);GO:0005811(lipid particle);GO:0006094(gluconeogenesis);GO:0061621(canonical glycolysis);GO:0051402(neuron apoptotic process);GO:0031640(killing of cells of other organism);GO:0016241(regulation of macroautophagy);GO:0097452(GAIT complex);GO:0097718(disordered domain specific binding);GO:0010951(negative regulation of endopeptidase activity);GO:0050715(positive regulation of cytokine secretion);GO:0051873(killing by host of symbiont cells);GO:0050832(defense response to fungus);GO:0019828(aspartic-type endopeptidase inhibitor activity);GO:0035605(peptidyl-cysteine S-nitrosylase activity);GO:0035606(peptidyl-cysteine S-trans-nitrosylation);GO:0052501(positive regulation by organism of apoptotic process in other organism involved in symbiotic interaction)","00010(Glycolysis / Gluconeogenesis);04066(HIF-1 signaling pathway);05010(Alzheimer's disease)","K00134","EC:1.2.1.12","glyceraldehyde-3-phosphate dehydrogenase [Source:HGNC Symbol;Acc:HGNC:4141]",{"v":9.152331,"d":"9.15"},{"v":172.20105,"d":"172.20"},{"v":0.0531491010072238,"d":"0.05"},{"v":-4.23381090033986,"d":"-4.23"},{"v":1.92452456637146e-08,"d":"0.00"},{"v":2.47928429298743e-06,"d":"0.00"},"down","yes"]
[95916,0,"chr19","+",8321634,8322396,"ENST00000417088",3,334,"MSTRG.7761","RPS28","GO:0003723(RNA binding);GO:0006412(translation);GO:0030529(intracellular ribonucleoprotein complex);GO:0005622(intracellular);GO:0003735(structural constituent of ribosome);GO:0005840(ribosome);GO:0005515(protein binding);GO:0022627(cytosolic small ribosomal subunit);GO:0042254(ribosome biogenesis);GO:0006364(rRNA processing);GO:0042274(ribosomal small subunit biogenesis);GO:0000028(ribosomal small subunit assembly);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0006413(translational initiation);GO:0030490(maturation of SSU-rRNA);GO:0000184(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay);GO:0019083(viral transcription);GO:0006614(SRP-dependent cotranslational protein targeting to membrane);GO:0015935(small ribosomal subunit)","03010(Ribosome)","NA","NA","ribosomal protein S28 [Source:HGNC Symbol;Acc:HGNC:10418]",{"v":228.549622,"d":"228.55"},{"v":13.033228,"d":"13.03"},{"v":17.5359183465524,"d":"17.54"},{"v":4.13224108061492,"d":"4.13"},{"v":1.98183926973053e-08,"d":"0.00"},{"v":2.53675426525507E-6,"d":"0.00"},"up","yes"]
[14700,0,"chr1","-",200969390,201023700,"ENST00000332129",34,9897,"MSTRG.1284","KIF21B","GO:0005737(cytoplasm);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0003777(microtubule motor activity);GO:0005856(cytoskeleton);GO:0042995(cell projection);GO:0008017(microtubule binding);GO:0005874(microtubule);GO:0031410(cytoplasmic vesicle);GO:0007018(microtubule-based movement);GO:0030425(dendrite);GO:0030424(axon);GO:0030426(growth cone);GO:0016887(ATPase activity);GO:0005871(kinesin complex)","NA","NA","NA","kinesin family member 21B [Source:HGNC Symbol;Acc:HGNC:29442]",{"v":4.603865,"d":"4.60"},{"v":0.261445,"d":"0.26"},{"v":17.6093059725755,"d":"17.61"},{"v":4.13826614490517,"d":"4.14"},{"v":2.01938671238702E-8,"d":"0.00"},{"v":2.55502563060814e-06,"d":"0.00"},"up","yes"]
[132575,0,"chr22","-",50525752,50530056,"ENST00000252029",10,1630,"MSTRG.10610","TYMP","GO:0016740(transferase activity);GO:0016757(transferase activity, transferring glycosyl groups);GO:0008083(growth factor activity);GO:0008152(metabolic process);GO:0007275(multicellular organism development);GO:0030154(cell differentiation);GO:0006935(chemotaxis);GO:0016763(transferase activity, transferring pentosyl groups);GO:0004645(phosphorylase activity);GO:0006206(pyrimidine nucleobase metabolic process);GO:0006213(pyrimidine nucleoside metabolic process);GO:0005829(cytosol);GO:0009032(thymidine phosphorylase activity);GO:0016154(pyrimidine-nucleoside phosphorylase activity);GO:0043097(pyrimidine nucleoside salvage);GO:0001525(angiogenesis);GO:0042803(protein homodimerization activity);GO:0046135(pyrimidine nucleoside catabolic process);GO:0000002(mitochondrial genome maintenance);GO:0031641(regulation of myelination);GO:0051969(regulation of transmission of nerve impulse);GO:1905333(regulation of gastric motility)","00240(Pyrimidine metabolism);00983(Drug metabolism - other enzymes);05219(Bladder cancer)","K00758","EC:2.4.2.4","thymidine phosphorylase [Source:HGNC Symbol;Acc:HGNC:3148]",{"v":13.858473,"d":"13.86"},{"v":0.76744,"d":"0.77"},{"v":18.058054049828,"d":"18.06"},{"v":4.17457053012463,"d":"4.17"},{"v":2.02170497614226E-8,"d":"0.00"},{"v":2.55502563060814e-06,"d":"0.00"},"up","yes"]
[189978,"j","chr9","-",35104123,35115913,"MSTRG.14745.6",9,3177,"MSTRG.14745","FAM214B","NA","NA","NA","NA","NA",{"v":0.51486,"d":"0.51"},{"v":10.02625,"d":"10.03"},{"v":0.0513512030918838,"d":"0.05"},{"v":-4.28345811236734,"d":"-4.28"},{"v":2.05073536741068E-8,"d":"0.00"},{"v":2.57541407650669e-06,"d":"0.00"},"down","yes"]
[117039,0,"chr2","+",181891985,181930738,"ENST00000409001",17,4987,"MSTRG.9290","SSFA2","GO:0005737(cytoplasm);GO:0005634(nucleus);GO:0005829(cytosol);GO:0003779(actin binding);GO:0005886(plasma membrane);GO:0005102(receptor binding);GO:0051015(actin filament binding)","NA","NA","NA","sperm specific antigen 2 [Source:HGNC Symbol;Acc:HGNC:11319]",{"v":0.180096,"d":"0.18"},{"v":3.587302,"d":"3.59"},{"v":0.0502037464367371,"d":"0.05"},{"v":-4.31606116097667,"d":"-4.32"},{"v":2.09608835577316e-08,"d":"0.00"},{"v":2.61591826800491e-06,"d":"0.00"},"down","yes"]
[36318,0,"chr11","-",123057489,123062136,"ENST00000533540",8,1826,"MSTRG.2940","HSPA8","GO:0003723(RNA binding);GO:0006397(mRNA processing);GO:0008380(RNA splicing);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0030529(intracellular ribonucleoprotein complex);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0005681(spliceosomal complex);GO:0042470(melanosome);GO:0005615(extracellular space);GO:0098793(presynapse);GO:0005730(nucleolus);GO:0005925(focal adhesion);GO:0005576(extracellular region);GO:0006986(response to unfolded protein);GO:0005654(nucleoplasm);GO:0045296(cadherin binding);GO:0070062(extracellular exosome);GO:0005622(intracellular);GO:0061024(membrane organization);GO:0072562(blood microparticle);GO:0043488(regulation of mRNA stability);GO:0016032(viral process);GO:0031012(extracellular matrix);GO:0006457(protein folding);GO:0043312(neutrophil degranulation);GO:0016887(ATPase activity);GO:0034774(secretory granule lumen);GO:1904813(ficolin-1-rich granule lumen);GO:0045892(negative regulation of transcription, DNA-templated);GO:0051082(unfolded protein binding);GO:0019899(enzyme binding);GO:0007269(neurotransmitter secretion);GO:0000398(mRNA splicing, via spliceosome);GO:0031625(ubiquitin protein ligase binding);GO:0000151(ubiquitin ligase complex);GO:1900034(regulation of cellular response to heat);GO:0042623(ATPase activity, coupled);GO:0001664(G-protein coupled receptor binding);GO:0031647(regulation of protein stability);GO:0006479(protein methylation);GO:0042026(protein refolding);GO:0031072(heat shock protein binding);GO:0023026(MHC class II protein complex binding);GO:0046034(ATP metabolic process);GO:0043254(regulation of protein complex assembly);GO:0061684(chaperone-mediated autophagy);GO:0043202(lysosomal lumen);GO:0055131(C3HC4-type RING finger domain binding);GO:0098575(lumenal side of lysosomal membrane);GO:0009267(cellular response to starvation);GO:0061635(regulation of protein complex stability);GO:0061740(protein targeting to lysosome involved in chaperone-mediated autophagy);GO:0061741(chaperone-mediated protein transport involved in chaperone-mediated autophagy);GO:1902904(negative regulation of supramolecular fiber organization);GO:1904589(regulation of protein import);GO:1904764(chaperone-mediated autophagy translocation complex disassembly);GO:0000974(Prp19 complex);GO:0005765(lysosomal membrane);GO:0061202(clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane);GO:0001786(phosphatidylserine binding);GO:0044788(modulation by host of viral process);GO:0044829(positive regulation by host of viral genome replication);GO:0048026(positive regulation of mRNA splicing, via spliceosome);GO:0051085(chaperone mediated protein folding requiring cofactor);GO:0051726(regulation of cell cycle);GO:0061738(late endosomal microautophagy);GO:0072318(clathrin coat disassembly);GO:0005770(late endosome);GO:0043209(myelin sheath)","03040(Spliceosome);04141(Protein processing in endoplasmic reticulum);04010(MAPK signaling pathway);04144(Endocytosis);04612(Antigen processing and presentation);04915(Estrogen signaling pathway);04213(Longevity regulating pathway - multiple species);05134(Legionellosis);05162(Measles);05164(Influenza A);05169(Epstein-Barr virus infection);05145(Toxoplasmosis)","NA","NA","heat shock protein family A (Hsp70) member 8 [Source:HGNC Symbol;Acc:HGNC:5241]",{"v":0.696492,"d":"0.70"},{"v":13.473683,"d":"13.47"},{"v":0.0516927702692723,"d":"0.05"},{"v":-4.27389366989259,"d":"-4.27"},{"v":2.18801702409999e-08,"d":"0.00"},{"v":2.71368471659805e-06,"d":"0.00"},"down","yes"]
[78655,"j","chr17","-",7240413,7251965,"MSTRG.6385.4",13,3619,"MSTRG.6385","CTDNEP1","NA","NA","NA","NA","NA",{"v":34.680828,"d":"34.68"},{"v":2.014144,"d":"2.01"},{"v":17.2186437513902,"d":"17.22"},{"v":4.10589960636772,"d":"4.11"},{"v":2.21679807048803e-08,"d":"0.00"},{"v":2.7324088809571e-06,"d":"0.00"},"up","yes"]
[98975,0,"chr19","-",19645203,19663693,"ENST00000357324",26,3861,"MSTRG.8026","ATP13A1","GO:0003674(molecular_function);GO:0008150(biological_process);GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0016787(hydrolase activity);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0006812(cation transport);GO:0099132(ATP hydrolysis coupled cation transmembrane transport);GO:0071421(manganese ion transmembrane transport);GO:0070588(calcium ion transmembrane transport);GO:0016887(ATPase activity);GO:0005887(integral component of plasma membrane);GO:0034220(ion transmembrane transport);GO:0006874(cellular calcium ion homeostasis);GO:0043231(intracellular membrane-bounded organelle);GO:0005388(calcium-transporting ATPase activity);GO:0015410(manganese-transporting ATPase activity)","NA","NA","NA","ATPase 13A1 [Source:HGNC Symbol;Acc:HGNC:24215]",{"v":0.405728,"d":"0.41"},{"v":7.74289,"d":"7.74"},{"v":0.0524000728410193,"d":"0.05"},{"v":-4.25428737252909,"d":"-4.25"},{"v":2.31475696935979E-8,"d":"0.00"},{"v":2.83564829228075e-06,"d":"0.00"},"down","yes"]
[52912,0,"chr14","+",22598237,22613215,"ENST00000428304",7,3366,"MSTRG.4171","ABHD4","GO:0016787(hydrolase activity);GO:0006629(lipid metabolic process);GO:0016042(lipid catabolic process);GO:0005789(endoplasmic reticulum membrane);GO:0036152(phosphatidylethanolamine acyl-chain remodeling)","NA","NA","NA","abhydrolase domain containing 4 [Source:HGNC Symbol;Acc:HGNC:20154]",{"v":0.773401,"d":"0.77"},{"v":14.540236,"d":"14.54"},{"v":0.0531904021365265,"d":"0.05"},{"v":-4.23269024553779,"d":"-4.23"},{"v":2.38172513418612e-08,"d":"0.00"},{"v":2.89989557801392e-06,"d":"0.00"},"down","yes"]
[57720,"j","chr14","+",91114670,91225716,"MSTRG.4612.22",14,3119,"MSTRG.4612","C14orf159","NA","NA","NA","NA","NA",{"v":0.357895,"d":"0.36"},{"v":6.900628,"d":"6.90"},{"v":0.0518641201931187,"d":"0.05"},{"v":-4.26911936834895,"d":"-4.27"},{"v":2.40005967100625E-8,"d":"0.00"},{"v":2.9045085764032E-6,"d":"0.00"},"down","yes"]
[58984,"j","chr14","+",103121431,103137439,"MSTRG.4696.2",14,3951,"MSTRG.4696","TNFAIP2","NA","NA","NA","NA","NA",{"v":0.401511,"d":"0.40"},{"v":7.64174,"d":"7.64"},{"v":0.0525418294786266,"d":"0.05"},{"v":-4.25038975455269,"d":"-4.25"},{"v":2.57369756842209e-08,"d":"0.00"},{"v":3.09587909917182e-06,"d":"0.00"},"down","yes"]
[30828,"j","chr11","-",64727032,64744633,"MSTRG.2519.8",18,2720,"MSTRG.2519","RASGRP2","NA","NA","NA","NA","NA",{"v":16.021267,"d":"16.02"},{"v":0.939015,"d":"0.94"},{"v":17.0617796307833,"d":"17.06"},{"v":4.09269622985548,"d":"4.09"},{"v":2.76420526407871e-08,"d":"0.00"},{"v":3.30512878521699E-6,"d":"0.00"},"up","yes"]
[123689,0,"chr20","+",38472816,38578861,"ENST00000262879",30,8663,"ENSG00000170471","RALGAPB","GO:0005096(GTPase activator activity);GO:0051056(regulation of small GTPase mediated signal transduction);GO:0090630(activation of GTPase activity);GO:0046982(protein heterodimerization activity);GO:0043547(positive regulation of GTPase activity)","NA","NA","NA","Ral GTPase activating protein non-catalytic beta subunit [Source:HGNC Symbol;Acc:HGNC:29221]",{"v":0.094773,"d":"0.09"},{"v":1.842542,"d":"1.84"},{"v":0.0514360052579534,"d":"0.05"},{"v":-4.2810775886783,"d":"-4.28"},{"v":2.92544636828803e-08,"d":"0.00"},{"v":3.4771019691652e-06,"d":"0.00"},"down","yes"]
[117326,0,"chr2","+",190180863,190203484,"ENST00000340623",2,4035,"MSTRG.9296","C2orf88","GO:0034237(protein kinase A regulatory subunit binding);GO:0016020(membrane);GO:0005886(plasma membrane);GO:0005515(protein binding)","NA","NA","NA","chromosome 2 open reading frame 88 [Source:HGNC Symbol;Acc:HGNC:28191]",{"v":0.622003,"d":"0.62"},{"v":11.417994,"d":"11.42"},{"v":0.0544756811047545,"d":"0.05"},{"v":-4.19824386042879,"d":"-4.20"},{"v":2.96040014075971E-8,"d":"0.00"},{"v":3.49782662785147E-6,"d":"0.00"},"down","yes"]
[66006,0,"chr15","+",85380715,85749355,"ENST00000394518",37,13215,"MSTRG.5391","AKAP13","GO:0006468(protein phosphorylation);GO:0035023(regulation of Rho protein signal transduction);GO:0004691(cAMP-dependent protein kinase activity);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0046872(metal ion binding);GO:0005829(cytosol);GO:0035556(intracellular signal transduction);GO:0005089(Rho guanyl-nucleotide exchange factor activity);GO:0043547(positive regulation of GTPase activity);GO:0005515(protein binding);GO:0007186(G-protein coupled receptor signaling pathway);GO:0005085(guanyl-nucleotide exchange factor activity);GO:0051056(regulation of small GTPase mediated signal transduction);GO:0007507(heart development);GO:0060348(bone development);GO:0005938(cell cortex);GO:0043123(positive regulation of I-kappaB kinase/NF-kappaB signaling);GO:0004871(signal transducer activity);GO:0030864(cortical actin cytoskeleton);GO:0043065(positive regulation of apoptotic process);GO:0017048(Rho GTPase binding);GO:0032947(protein complex scaffold);GO:0051018(protein kinase A binding);GO:0035025(positive regulation of Rho protein signal transduction);GO:0055007(cardiac muscle cell differentiation);GO:0005078(MAP-kinase scaffold activity);GO:0060297(regulation of sarcomere organization);GO:0071875(adrenergic receptor signaling pathway);GO:0086023(adrenergic receptor signaling pathway involved in heart process);GO:0010611(regulation of cardiac muscle hypertrophy);GO:0045859(regulation of protein kinase activity);GO:0051168(nuclear export);GO:0071883(activation of MAPK activity by adrenergic receptor signaling pathway);GO:1900169(regulation of glucocorticoid mediated signaling pathway);GO:0005884(actin filament);GO:0015629(actin cytoskeleton);GO:0048471(perinuclear region of cytoplasm);GO:0005622(intracellular)","NA","NA","NA","A-kinase anchoring protein 13 [Source:HGNC Symbol;Acc:HGNC:371]",{"v":0.222872,"d":"0.22"},{"v":4.072028,"d":"4.07"},{"v":0.0547324330775721,"d":"0.05"},{"v":-4.19146019818592,"d":"-4.19"},{"v":3.01321076846382e-08,"d":"0.00"},{"v":3.53048306619889e-06,"d":"0.00"},"down","yes"]
[89771,"j","chr17","+",82228445,82239494,"MSTRG.7355.5",5,1999,"MSTRG.7355","SLC16A3","NA","NA","NA","NA","NA",{"v":0.377546,"d":"0.38"},{"v":7.316832,"d":"7.32"},{"v":0.0515996540579311,"d":"0.05"},{"v":-4.27649479642426,"d":"-4.28"},{"v":3.03156033210166e-08,"d":"0.00"},{"v":3.53048306619889e-06,"d":"0.00"},"down","yes"]
[11194,0,"chr1","+",153728067,153774808,"ENST00000318967",30,5235,"MSTRG.986","INTS3","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005730(nucleolus);GO:0005515(protein binding);GO:0006281(DNA repair);GO:0006974(cellular response to DNA damage stimulus);GO:0005654(nucleoplasm);GO:0042795(snRNA transcription from RNA polymerase II promoter);GO:0007093(mitotic cell cycle checkpoint);GO:0010212(response to ionizing radiation);GO:0032039(integrator complex);GO:0016180(snRNA processing);GO:0070876(SOSS complex)","NA","NA","NA","integrator complex subunit 3 [Source:HGNC Symbol;Acc:HGNC:26153]",{"v":0.119314,"d":"0.12"},{"v":2.346706,"d":"2.35"},{"v":0.050843181889849,"d":"0.05"},{"v":-4.29780186924577,"d":"-4.30"},{"v":3.04108116679792e-08,"d":"0.00"},{"v":3.53048306619889e-06,"d":"0.00"},"down","yes"]
[84148,0,"chr17","+",44308559,44318671,"ENST00000426726",11,2048,"MSTRG.6890","RUNDC3A","GO:0050790(regulation of catalytic activity);GO:0005515(protein binding);GO:0031284(positive regulation of guanylate cyclase activity);GO:0030695(GTPase regulator activity);GO:0007264(small GTPase mediated signal transduction);GO:0030250(guanylate cyclase activator activity);GO:0051428(peptide hormone receptor binding);GO:0030828(positive regulation of cGMP biosynthetic process);GO:0005829(cytosol);GO:0005886(plasma membrane)","NA","NA","NA","RUN domain containing 3A [Source:HGNC Symbol;Acc:HGNC:16984]",{"v":12.992619,"d":"12.99"},{"v":0.757484,"d":"0.76"},{"v":17.1523345707632,"d":"17.15"},{"v":4.10033304705462,"d":"4.10"},{"v":3.10089221973405e-08,"d":"0.00"},{"v":3.57911074240748E-6,"d":"0.00"},"up","yes"]
[88711,0,"chr17","-",78112921,78127020,"ENST00000392467",19,2833,"MSTRG.7280","TMC6","GO:0006810(transport);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005794(Golgi apparatus);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0006811(ion transport);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0008150(biological_process);GO:0070062(extracellular exosome);GO:0043312(neutrophil degranulation);GO:0035579(specific granule membrane);GO:0070821(tertiary granule membrane);GO:0031965(nuclear membrane)","NA","NA","NA","transmembrane channel like 6 [Source:HGNC Symbol;Acc:HGNC:18021]",{"v":0.535492,"d":"0.54"},{"v":9.976024,"d":"9.98"},{"v":0.053677898128553,"d":"0.05"},{"v":-4.21952800890134,"d":"-4.22"},{"v":3.15331803565118E-8,"d":"0.00"},{"v":3.61870428367143E-6,"d":"0.00"},"down","yes"]
[65694,0,"chr15","-",82536759,82540131,"ENST00000561068",5,522,"MSTRG.5381","RPS17","GO:0003723(RNA binding);GO:0016020(membrane);GO:0006412(translation);GO:0006413(translational initiation);GO:0030529(intracellular ribonucleoprotein complex);GO:0005622(intracellular);GO:0003735(structural constituent of ribosome);GO:0005840(ribosome);GO:0022627(cytosolic small ribosomal subunit);GO:0005925(focal adhesion);GO:0006364(rRNA processing);GO:0042274(ribosomal small subunit biogenesis);GO:0000028(ribosomal small subunit assembly);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0031012(extracellular matrix);GO:0000184(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay);GO:0019083(viral transcription);GO:0006614(SRP-dependent cotranslational protein targeting to membrane);GO:0034101(erythrocyte homeostasis)","03010(Ribosome)","NA","NA","ribosomal protein S17 [Source:HGNC Symbol;Acc:HGNC:10397]",{"v":27.552776,"d":"27.55"},{"v":1.568308,"d":"1.57"},{"v":17.5684725194286,"d":"17.57"},{"v":4.13491685740941,"d":"4.13"},{"v":3.19907517207188e-08,"d":"0.00"},{"v":3.65023617348179e-06,"d":"0.00"},"up","yes"]
[115653,0,"chr2","-",159771851,159904710,"ENST00000504764",39,5650,"MSTRG.9190","LY75-CD302","NA","NA","NA","NA","LY75-CD302 readthrough [Source:HGNC Symbol;Acc:HGNC:38828]",{"v":2.465073,"d":"2.47"},{"v":0.139389,"d":"0.14"},{"v":17.6848460064998,"d":"17.68"},{"v":4.14444175149327,"d":"4.14"},{"v":3.32108531682273e-08,"d":"0.00"},{"v":3.76792225035888e-06,"d":"0.00"},"up","yes"]
[41998,0,"chr12","-",53038967,53047050,"ENST00000546566",4,1650,"MSTRG.3389","AC068888.1","NA","NA","NA","NA","NA",{"v":0.452512,"d":"0.45"},{"v":8.735533,"d":"8.74"},{"v":0.0518013039387522,"d":"0.05"},{"v":-4.27086777598848,"d":"-4.27"},{"v":3.45058306164288E-8,"d":"0.00"},{"v":3.89272556920254e-06,"d":"0.00"},"down","yes"]
[94083,"j","chr19","-",1010695,1020942,"MSTRG.7589.8",11,1413,"MSTRG.7589","TMEM259","NA","NA","NA","NA","NA",{"v":31.199741,"d":"31.20"},{"v":1.880661,"d":"1.88"},{"v":16.5897740209426,"d":"16.59"},{"v":4.05222232951834,"d":"4.05"},{"v":3.4805251898059e-08,"d":"0.00"},{"v":3.90444533651934E-6,"d":"0.00"},"up","yes"]
[49305,"j","chr13","+",27620771,27667415,"MSTRG.3928.5",4,2848,"MSTRG.3928","POLR1D","NA","NA","NA","NA","NA",{"v":0.553344,"d":"0.55"},{"v":10.072493,"d":"10.07"},{"v":0.0549361513579607,"d":"0.05"},{"v":-4.18610034618424,"d":"-4.19"},{"v":3.58190003760826E-8,"d":"0.00"},{"v":3.9833525509495e-06,"d":"0.00"},"down","yes"]
[67259,"j","chr16","-",83298,138361,"MSTRG.5474.3",13,3069,"MSTRG.5474","NPRL3","NA","NA","NA","NA","NA",{"v":31.673975,"d":"31.67"},{"v":1.938895,"d":"1.94"},{"v":16.3360960753419,"d":"16.34"},{"v":4.02999135097402,"d":"4.03"},{"v":3.59076251587996e-08,"d":"0.00"},{"v":3.9833525509495e-06,"d":"0.00"},"up","yes"]
[69987,"j","chr16","-",15593901,15643060,"MSTRG.5695.1",27,8119,"MSTRG.5695","MARF1","NA","NA","NA","NA","NA",{"v":1.048244,"d":"1.05"},{"v":18.333487,"d":"18.33"},{"v":0.0571764662118014,"d":"0.06"},{"v":-4.12843473273423,"d":"-4.13"},{"v":3.88318047902242e-08,"d":"0.00"},{"v":4.28394186768617e-06,"d":"0.00"},"down","yes"]
[183629,0,"chr8","+",47260955,47713441,"ENST00000524141",15,2761,"MSTRG.14343","SPIDR","GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0006281(DNA repair);GO:0006310(DNA recombination);GO:0006974(cellular response to DNA damage stimulus);GO:0005515(protein binding);GO:0010569(regulation of double-strand break repair via homologous recombination);GO:0000724(double-strand break repair via homologous recombination);GO:0031334(positive regulation of protein complex assembly);GO:0000228(nuclear chromosome);GO:0071479(cellular response to ionizing radiation);GO:0072711(cellular response to hydroxyurea);GO:0072757(cellular response to camptothecin);GO:2000781(positive regulation of double-strand break repair);GO:0070202(regulation of establishment of protein localization to chromosome)","NA","NA","NA","scaffolding protein involved in DNA repair [Source:HGNC Symbol;Acc:HGNC:28971]",{"v":0.2637,"d":"0.26"},{"v":4.928141,"d":"4.93"},{"v":0.0535090209472497,"d":"0.05"},{"v":-4.22407405753643,"d":"-4.22"},{"v":4.46337573636286e-08,"d":"0.00"},{"v":4.89696080789525E-6,"d":"0.00"},"down","yes"]
[19464,0,"chr10","+",31319125,31529202,"ENST00000320985",9,5423,"ENSG00000148516","ZEB1","GO:0045602(negative regulation of endothelial cell differentiation);GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0007399(nervous system development);GO:0030154(cell differentiation);GO:0005515(protein binding);GO:0003713(transcription coactivator activity);GO:0006955(immune response);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0045892(negative regulation of transcription, DNA-templated);GO:0003714(transcription corepressor activity);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0070888(E-box binding);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0008283(cell proliferation);GO:0008270(zinc ion binding);GO:0001227(transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding);GO:0045666(positive regulation of neuron differentiation);GO:0003682(chromatin binding);GO:0008134(transcription factor binding);GO:0007389(pattern specification process);GO:0007417(central nervous system development);GO:0008285(negative regulation of cell proliferation);GO:0010464(regulation of mesenchymal cell proliferation);GO:0017015(regulation of transforming growth factor beta receptor signaling pathway);GO:0030857(negative regulation of epithelial cell differentiation);GO:0033081(regulation of T cell differentiation in thymus);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0048513(animal organ development);GO:0048596(embryonic camera-type eye morphogenesis);GO:0048598(embryonic morphogenesis);GO:0048704(embryonic skeletal system morphogenesis);GO:0048752(semicircular canal morphogenesis);GO:0051150(regulation of smooth muscle cell differentiation);GO:0051216(cartilage development);GO:0071230(cellular response to amino acid stimulus);GO:0090103(cochlea morphogenesis);GO:0005667(transcription factor complex)","05202(Transcriptional misregulation in cancers);05206(MicroRNAs in cancer);05215(Prostate cancer)","K09299","NA","zinc finger E-box binding homeobox 1 [Source:HGNC Symbol;Acc:HGNC:11642]",{"v":0.149675,"d":"0.15"},{"v":2.805742,"d":"2.81"},{"v":0.0533459598209671,"d":"0.05"},{"v":-4.22847717771229,"d":"-4.23"},{"v":4.50845034361001e-08,"d":"0.00"},{"v":4.91938450607675e-06,"d":"0.00"},"down","yes"]
[66892,0,"chr15","+",98649044,98964529,"ENST00000558762",21,11726,"ENSG00000140443","IGF1R","GO:0030335(positive regulation of cell migration);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0004713(protein tyrosine kinase activity);GO:0007169(transmembrane receptor protein tyrosine kinase signaling pathway);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0004714(transmembrane receptor protein tyrosine kinase activity);GO:0046777(protein autophosphorylation);GO:0042802(identical protein binding);GO:0005887(integral component of plasma membrane);GO:0043548(phosphatidylinositol 3-kinase binding);GO:0043560(insulin receptor substrate binding);GO:0043066(negative regulation of apoptotic process);GO:0007165(signal transduction);GO:0043235(receptor complex);GO:0006955(immune response);GO:0051262(protein tetramerization);GO:0008284(positive regulation of cell proliferation);GO:0046328(regulation of JNK cascade);GO:0045740(positive regulation of DNA replication);GO:0005158(insulin receptor binding);GO:0008286(insulin receptor signaling pathway);GO:0014065(phosphatidylinositol 3-kinase signaling);GO:0048009(insulin-like growth factor receptor signaling pathway);GO:0048015(phosphatidylinositol-mediated signaling);GO:0035867(alphav-beta3 integrin-IGF-1-IGF1R complex);GO:0031994(insulin-like growth factor I binding);GO:0043559(insulin binding);GO:0005010(insulin-like growth factor-activated receptor activity);GO:0005520(insulin-like growth factor binding);GO:0038083(peptidyl-tyrosine autophosphorylation);GO:0051389(inactivation of MAPKK activity);GO:0043231(intracellular membrane-bounded organelle);GO:0018108(peptidyl-tyrosine phosphorylation)","04014(Ras signaling pathway);04015(Rap1 signaling pathway);04010(MAPK signaling pathway);04066(HIF-1 signaling pathway);04068(FoxO signaling pathway);04151(PI3K-Akt signaling pathway);04152(AMPK signaling pathway);04150(mTOR signaling pathway);04144(Endocytosis);04140(Autophagy - animal);04114(Oocyte meiosis);04510(Focal adhesion);04520(Adherens junction);04550(Signaling pathways regulating pluripotency of stem cells);04913(Ovarian Steroidogenesis);04914(Progesterone-mediated oocyte maturation);04730(Long-term depression);04211(Longevity regulating pathway - mammal);04213(Longevity regulating pathway - multiple species);05200(Pathways in cancer);05202(Transcriptional misregulation in cancers);05205(Proteoglycans in cancer);05225(Hepatocellular carcinoma);05214(Glioma);05218(Melanoma);05215(Prostate cancer);05224(Breast cancer);01521(EGFR tyrosine kinase inhibitor resistance);01522(Endocrine resistance)","K05087","EC:2.7.10.1","insulin like growth factor 1 receptor [Source:HGNC Symbol;Acc:HGNC:5465]",{"v":0.101423,"d":"0.10"},{"v":1.830454,"d":"1.83"},{"v":0.0554086581798832,"d":"0.06"},{"v":-4.17374475976025,"d":"-4.17"},{"v":4.56416314047306e-08,"d":"0.00"},{"v":4.95310921679163e-06,"d":"0.00"},"down","yes"]
[145033,0,"chr4","-",849278,932373,"ENST00000511163",25,4280,"MSTRG.11486","GAK","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005794(Golgi apparatus);GO:0043231(intracellular membrane-bounded organelle);GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0005515(protein binding);GO:0007049(cell cycle);GO:0048471(perinuclear region of cytoplasm);GO:0045202(synapse);GO:0030054(cell junction);GO:0005925(focal adhesion);GO:0005829(cytosol);GO:0061024(membrane organization);GO:0051087(chaperone binding);GO:0007030(Golgi organization);GO:0010977(negative regulation of neuron projection development);GO:0030332(cyclin binding);GO:0006898(receptor-mediated endocytosis);GO:0007029(endoplasmic reticulum organization);GO:0016191(synaptic vesicle uncoating);GO:0051085(chaperone mediated protein folding requiring cofactor);GO:0072318(clathrin coat disassembly);GO:0072583(clathrin-dependent endocytosis);GO:0072600(establishment of protein localization to Golgi);GO:0090002(establishment of protein localization to plasma membrane);GO:0090160(Golgi to lysosome transport);GO:1905224(clathrin-coated pit assembly);GO:0031982(vesicle)","NA","NA","NA","cyclin G associated kinase [Source:HGNC Symbol;Acc:HGNC:4113]",{"v":4.853631,"d":"4.85"},{"v":0.293497,"d":"0.29"},{"v":16.5372422886776,"d":"16.54"},{"v":4.04764676904853,"d":"4.05"},{"v":4.64334498979023e-08,"d":"0.00"},{"v":5.01180068952061e-06,"d":"0.00"},"up","yes"]
[83132,0,"chr17","-",40554330,40561013,"ENST00000579344",3,1874,"MSTRG.6803","CCR7","GO:0051897(positive regulation of protein kinase B signaling);GO:0070374(positive regulation of ERK1 and ERK2 cascade);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0004930(G-protein coupled receptor activity);GO:0007186(G-protein coupled receptor signaling pathway);GO:0005886(plasma membrane);GO:0004871(signal transducer activity);GO:0007165(signal transduction);GO:0006955(immune response);GO:0004950(chemokine receptor activity);GO:0016493(C-C chemokine receptor activity);GO:0006935(chemotaxis);GO:0006954(inflammatory response);GO:0070098(chemokine-mediated signaling pathway);GO:0002606(positive regulation of dendritic cell antigen processing and presentation);GO:0002885(positive regulation of hypersensitivity);GO:0002922(positive regulation of humoral immune response);GO:0032496(response to lipopolysaccharide);GO:0032649(regulation of interferon-gamma production);GO:0032735(positive regulation of interleukin-12 production);GO:0045060(negative thymic T cell selection);GO:0048872(homeostasis of number of cells);GO:0050706(regulation of interleukin-1 beta secretion);GO:0050862(positive regulation of T cell receptor signaling pathway);GO:0072610(interleukin-12 secretion);GO:0090023(positive regulation of neutrophil chemotaxis);GO:0097029(mature conventional dendritic cell differentiation);GO:2000510(positive regulation of dendritic cell chemotaxis);GO:2000522(positive regulation of immunological synapse formation);GO:2000525(positive regulation of T cell costimulation);GO:2000526(positive regulation of glycoprotein biosynthetic process involved in immunological synapse formation);GO:0005622(intracellular);GO:0009897(external side of plasma membrane);GO:0009986(cell surface);GO:0071345(cellular response to cytokine stimulus);GO:0030838(positive regulation of actin filament polymerization);GO:0051491(positive regulation of filopodium assembly);GO:0046330(positive regulation of JNK cascade);GO:0001768(establishment of T cell polarity);GO:0001954(positive regulation of cell-matrix adhesion);GO:0002407(dendritic cell chemotaxis);GO:0031274(positive regulation of pseudopodium assembly);GO:0031529(ruffle organization);GO:0034695(response to prostaglandin E);GO:0043123(positive regulation of I-kappaB kinase/NF-kappaB signaling);GO:0043552(positive regulation of phosphatidylinositol 3-kinase activity);GO:0045860(positive regulation of protein kinase activity);GO:0051209(release of sequestered calcium ion into cytosol);GO:0090630(activation of GTPase activity);GO:2000107(negative regulation of leukocyte apoptotic process);GO:2000147(positive regulation of cell motility);GO:0007204(positive regulation of cytosolic calcium ion concentration);GO:0045785(positive regulation of cell adhesion);GO:0035757(chemokine (C-C motif) ligand 19 binding);GO:0035758(chemokine (C-C motif) ligand 21 binding);GO:0038117(C-C motif chemokine 19 receptor activity);GO:0038121(C-C motif chemokine 21 receptor activity);GO:0002408(myeloid dendritic cell chemotaxis);GO:0038115(chemokine (C-C motif) ligand 19 signaling pathway);GO:0038116(chemokine (C-C motif) ligand 21 signaling pathway);GO:0071731(response to nitric oxide);GO:0097022(lymphocyte migration into lymph node);GO:2000547(regulation of dendritic cell dendrite assembly)","04060(Cytokine-cytokine receptor interaction);04062(Chemokine signaling pathway)","K04182","NA","C-C motif chemokine receptor 7 [Source:HGNC Symbol;Acc:HGNC:1608]",{"v":7.4477,"d":"7.45"},{"v":0.438545,"d":"0.44"},{"v":16.9827497748236,"d":"16.98"},{"v":4.0859981677546,"d":"4.09"},{"v":4.71015025071107e-08,"d":"0.00"},{"v":5.05657420463434e-06,"d":"0.00"},"up","yes"]
[7064,"j","chr1","-",68098498,68232540,"MSTRG.637.2",12,2013,"MSTRG.637","WLS","NA","NA","NA","NA","NA",{"v":0.780044,"d":"0.78"},{"v":13.705074,"d":"13.71"},{"v":0.0569164383935468,"d":"0.06"},{"v":-4.13501080325699,"d":"-4.14"},{"v":5.10009812435311e-08,"d":"0.00"},{"v":5.44592295973705e-06,"d":"0.00"},"down","yes"]
[3288,"j","chr1","-",27612589,27626135,"MSTRG.298.9",13,2077,"MSTRG.298","FGR","NA","NA","NA","NA","NA",{"v":1.42165,"d":"1.42"},{"v":24.411188,"d":"24.41"},{"v":0.0582376408718822,"d":"0.06"},{"v":-4.10190427468061,"d":"-4.10"},{"v":5.13937857203194e-08,"d":"0.00"},{"v":5.45867613437945e-06,"d":"0.00"},"down","yes"]
[4061,"j","chr1","-",33323625,33349680,"MSTRG.401.3",8,2331,"MSTRG.401","PHC2","NA","NA","NA","NA","NA",{"v":0.655994,"d":"0.66"},{"v":11.453419,"d":"11.45"},{"v":0.0572749499516258,"d":"0.06"},{"v":-4.12595189690951,"d":"-4.13"},{"v":5.25628039533654e-08,"d":"0.00"},{"v":5.55330195418412e-06,"d":"0.00"},"down","yes"]
[89784,0,"chr17","+",82233687,82240086,"ENST00000581287",4,4830,"MSTRG.7355","SLC16A3","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0055085(transmembrane transport);GO:0005887(integral component of plasma membrane);GO:0008028(monocarboxylic acid transmembrane transporter activity);GO:0015129(lactate transmembrane transporter activity);GO:0015718(monocarboxylic acid transport);GO:0035873(lactate transmembrane transport);GO:0003723(RNA binding);GO:0006810(transport);GO:0031965(nuclear membrane);GO:0005886(plasma membrane);GO:0015293(symporter activity);GO:0005515(protein binding);GO:0050900(leukocyte migration);GO:0006090(pyruvate metabolic process);GO:0035879(plasma membrane lactate transport)","05230(Central carbon metabolism in cancer)","K08180","NA","solute carrier family 16 member 3 [Source:HGNC Symbol;Acc:HGNC:10924]",{"v":4.891705,"d":"4.89"},{"v":0.303777,"d":"0.30"},{"v":16.1029472277361,"d":"16.10"},{"v":4.0092528553832,"d":"4.01"},{"v":5.49252594017382e-08,"d":"0.00"},{"v":5.77235568281005e-06,"d":"0.00"},"up","yes"]
[47608,"j","chr12","-",121237830,121296695,"MSTRG.3802.7",15,4581,"MSTRG.3802","CAMKK2","NA","NA","NA","NA","NA",{"v":0.375267,"d":"0.38"},{"v":6.477366,"d":"6.48"},{"v":0.0579351236289566,"d":"0.06"},{"v":-4.10941793099286,"d":"-4.11"},{"v":5.59433579203405e-08,"d":"0.00"},{"v":5.84857052855162e-06,"d":"0.00"},"down","yes"]
[32853,0,"chr11","+",72814427,72829633,"ENST00000544490",17,3731,"MSTRG.2695","ATG16L2","GO:0006810(transport);GO:0005737(cytoplasm);GO:0015031(protein transport);GO:0005654(nucleoplasm);GO:0006914(autophagy);GO:0000045(autophagosome assembly);GO:0000421(autophagosome membrane);GO:0039689(negative stranded viral RNA replication)","04140(Autophagy - animal)","NA","NA","autophagy related 16 like 2 [Source:HGNC Symbol;Acc:HGNC:25464]",{"v":3.710215,"d":"3.71"},{"v":0.224642,"d":"0.22"},{"v":16.5161234319495,"d":"16.52"},{"v":4.0458032004223,"d":"4.05"},{"v":5.74565171910011e-08,"d":"0.00"},{"v":5.97547778786412e-06,"d":"0.00"},"up","yes"]
[87178,0,"chr17","-",67077972,67245183,"ENST00000580168",33,6279,"MSTRG.7118","HELZ","GO:0003723(RNA binding);GO:0005634(nucleus);GO:0016020(membrane);GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0016787(hydrolase activity);GO:0004386(helicase activity);GO:0016021(integral component of membrane)","NA","NA","NA","helicase with zinc finger [Source:HGNC Symbol;Acc:HGNC:16878]",{"v":0.110152,"d":"0.11"},{"v":2.00649,"d":"2.01"},{"v":0.0548978564558009,"d":"0.05"},{"v":-4.18710637098068,"d":"-4.19"},{"v":5.86141576191195e-08,"d":"0.00"},{"v":6.06428756133978e-06,"d":"0.00"},"down","yes"]
[79884,"j","chr17","+",16438993,16441570,"MSTRG.6464.7",4,751,"MSTRG.6464","LRRC75A-AS1","NA","NA","NA","NA","NA",{"v":47.247013,"d":"47.25"},{"v":2.997063,"d":"3.00"},{"v":15.7644377178591,"d":"15.76"},{"v":3.97860180812948,"d":"3.98"},{"v":5.9562715839532e-08,"d":"0.00"},{"v":6.12012890055605e-06,"d":"0.00"},"up","yes"]
[134952,0,"chr3","-",39263495,39281273,"ENST00000541347",2,3255,"MSTRG.10821","CX3CR1","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0004930(G-protein coupled receptor activity);GO:0007186(G-protein coupled receptor signaling pathway);GO:0007155(cell adhesion);GO:0005886(plasma membrane);GO:0004871(signal transducer activity);GO:0007165(signal transduction);GO:0006935(chemotaxis);GO:0070098(chemokine-mediated signaling pathway);GO:0005515(protein binding);GO:0016032(viral process);GO:0005887(integral component of plasma membrane);GO:0016495(C-X3-C chemokine receptor activity);GO:0009611(response to wounding);GO:0004950(chemokine receptor activity);GO:0006968(cellular defense response);GO:0019960(C-X3-C chemokine binding);GO:0004896(cytokine receptor activity);GO:0001774(microglial cell activation);GO:0002052(positive regulation of neuroblast proliferation);GO:0002282(microglial cell activation involved in immune response);GO:0002881(negative regulation of chronic inflammatory response to non-antigenic stimulus);GO:0007613(memory);GO:0016525(negative regulation of angiogenesis);GO:0019221(cytokine-mediated signaling pathway);GO:0021795(cerebral cortex cell migration);GO:0030336(negative regulation of cell migration);GO:0045766(positive regulation of angiogenesis);GO:0048246(macrophage chemotaxis);GO:0071222(cellular response to lipopolysaccharide);GO:0071560(cellular response to transforming growth factor beta stimulus);GO:1900272(negative regulation of long-term synaptic potentiation);GO:2001240(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand);GO:0032809(neuronal cell body membrane);GO:0043005(neuron projection);GO:0048471(perinuclear region of cytoplasm)","04060(Cytokine-cytokine receptor interaction);04062(Chemokine signaling pathway)","K04192","NA","C-X3-C motif chemokine receptor 1 [Source:HGNC Symbol;Acc:HGNC:2558]",{"v":0.20067,"d":"0.20"},{"v":3.620754,"d":"3.62"},{"v":0.055422157926222,"d":"0.06"},{"v":-4.17339330485129,"d":"-4.17"},{"v":5.98581263719399e-08,"d":"0.00"},{"v":6.12012890055605e-06,"d":"0.00"},"down","yes"]
[12971,"j","chr1","-",161541756,161550911,"MSTRG.1160.5",6,2461,"MSTRG.1160","FCGR3A","NA","NA","NA","NA","NA",{"v":0.690734,"d":"0.69"},{"v":11.881179,"d":"11.88"},{"v":0.0581368229533449,"d":"0.06"},{"v":-4.10440395618655,"d":"-4.10"},{"v":6.00733806344644e-08,"d":"0.00"},{"v":6.12012890055605e-06,"d":"0.00"},"down","yes"]
[119067,"j","chr2","+",218382229,218395343,"MSTRG.9417.8",14,1958,"MSTRG.9417","SLC11A1","NA","NA","NA","NA","NA",{"v":0.622983,"d":"0.62"},{"v":10.755169,"d":"10.76"},{"v":0.0579240549358174,"d":"0.06"},{"v":-4.10969358888976,"d":"-4.11"},{"v":6.36212731637504e-08,"d":"0.00"},{"v":6.44867808392775e-06,"d":"0.00"},"down","yes"]
[49860,0,"chr13","-",40469953,40611129,"ENST00000636651",4,1773,"MSTRG.3955","FOXO1","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0005829(cytosol);GO:0005739(mitochondrion);GO:0043565(sequence-specific DNA binding);GO:0005515(protein binding);GO:0006974(cellular response to DNA damage stimulus);GO:0006915(apoptotic process);GO:0030154(cell differentiation);GO:0006914(autophagy);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0045893(positive regulation of transcription, DNA-templated);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0005654(nucleoplasm);GO:0045444(fat cell differentiation);GO:0010508(positive regulation of autophagy);GO:0003682(chromatin binding);GO:0009267(cellular response to starvation);GO:0000981(RNA polymerase II transcription factor activity, sequence-specific DNA binding);GO:0043065(positive regulation of apoptotic process);GO:0031625(ubiquitin protein ligase binding);GO:0009653(anatomical structure morphogenesis);GO:0034599(cellular response to oxidative stress);GO:0043066(negative regulation of apoptotic process);GO:0045892(negative regulation of transcription, DNA-templated);GO:0045599(negative regulation of fat cell differentiation);GO:0008286(insulin receptor signaling pathway);GO:0001678(cellular glucose homeostasis);GO:0032869(cellular response to insulin stimulus);GO:2000505(regulation of energy homeostasis);GO:0031018(endocrine pancreas development);GO:0008013(beta-catenin binding);GO:0051721(protein phosphatase 2A binding);GO:0045732(positive regulation of protein catabolic process);GO:0001659(temperature homeostasis);GO:0071455(cellular response to hyperoxia);GO:0032873(negative regulation of stress-activated MAPK cascade);GO:0071732(cellular response to nitric oxide);GO:0006473(protein acetylation);GO:0000989(transcription factor activity, transcription factor binding);GO:0001078(transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0001223(transcription coactivator binding);GO:0001227(transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding);GO:0008134(transcription factor binding);GO:0001568(blood vessel development);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0032868(response to insulin);GO:0035947(regulation of gluconeogenesis by regulation of transcription from RNA polymerase II promoter);GO:0042127(regulation of cell proliferation);GO:0042593(glucose homeostasis);GO:0045722(positive regulation of gluconeogenesis);GO:0070166(enamel mineralization);GO:0070301(cellular response to hydrogen peroxide);GO:0070417(cellular response to cold);GO:0071549(cellular response to dexamethasone stimulus);GO:0090090(negative regulation of canonical Wnt signaling pathway);GO:0097150(neuronal stem cell population maintenance);GO:1902617(response to fluoride);GO:2000177(regulation of neural precursor cell proliferation);GO:2000377(regulation of reactive oxygen species metabolic process)","04068(FoxO signaling pathway);04152(AMPK signaling pathway);04218(Cellular senescence);04910(Insulin signaling pathway);04922(Glucagon signaling pathway);04919(Thyroid hormone signaling pathway);04211(Longevity regulating pathway - mammal);04213(Longevity regulating pathway - multiple species);05200(Pathways in cancer);05202(Transcriptional misregulation in cancers);05215(Prostate cancer);04931(Insulin resistance);04933(AGE-RAGE signaling pathway in diabetic complications);05165(Human papillomavirus infection)","NA","NA","forkhead box O1 [Source:HGNC Symbol;Acc:HGNC:3819]",{"v":8.450751,"d":"8.45"},{"v":0.523811,"d":"0.52"},{"v":16.1332064427818,"d":"16.13"},{"v":4.01196129465641,"d":"4.01"},{"v":6.46053639939243e-08,"d":"0.00"},{"v":6.51535307187213e-06,"d":"0.00"},"up","yes"]
[96694,"j","chr19","-",11300542,11339664,"MSTRG.7821.2",6,5786,"MSTRG.7821","RAB3D","NA","NA","NA","NA","NA",{"v":1.046185,"d":"1.05"},{"v":17.319786,"d":"17.32"},{"v":0.0604040373247106,"d":"0.06"},{"v":-4.0492112092032,"d":"-4.05"},{"v":6.55410982043072e-08,"d":"0.00"},{"v":6.57650577358596e-06,"d":"0.00"},"down","yes"]
[12336,0,"chr1","+",158179947,158184896,"ENST00000368171",7,2253,"MSTRG.1099","CD1D","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005783(endoplasmic reticulum);GO:0005765(lysosomal membrane);GO:0005789(endoplasmic reticulum membrane);GO:0005886(plasma membrane);GO:0002376(immune system process);GO:0045087(innate immune response);GO:0005764(lysosome);GO:0050776(regulation of immune response);GO:0005887(integral component of plasma membrane);GO:0005768(endosome);GO:0016323(basolateral plasma membrane);GO:0004872(receptor activity);GO:0010008(endosome membrane);GO:0016032(viral process);GO:0009986(cell surface);GO:0042393(histone binding);GO:0045089(positive regulation of innate immune response);GO:0016045(detection of bacterium);GO:0042102(positive regulation of T cell proliferation);GO:0045058(T cell selection);GO:0030881(beta-2-microglobulin binding);GO:0050839(cell adhesion molecule binding);GO:0030883(endogenous lipid antigen binding);GO:0071723(lipopeptide binding);GO:0048007(antigen processing and presentation, exogenous lipid antigen via MHC class Ib);GO:0030882(lipid antigen binding);GO:0030884(exogenous lipid antigen binding);GO:0034113(heterotypic cell-cell adhesion);GO:0048006(antigen processing and presentation, endogenous lipid antigen via MHC class Ib)","04530(Tight junction);04640(Hematopoietic cell lineage);05146(Amoebiasis)","K06448","NA","CD1d molecule [Source:HGNC Symbol;Acc:HGNC:1637]",{"v":5.883247,"d":"5.88"},{"v":0.362453,"d":"0.36"},{"v":16.2317514270816,"d":"16.23"},{"v":4.02074677184281,"d":"4.02"},{"v":6.62640496871126e-08,"d":"0.00"},{"v":6.61580272076132e-06,"d":"0.00"},"up","yes"]
[26687,0,"chr11","-",10852864,10858036,"ENST00000413761",3,2512,"MSTRG.2253","ZBED5","GO:0003676(nucleic acid binding);GO:0046872(metal ion binding);GO:0003677(DNA binding);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0005737(cytoplasm);GO:0000981(RNA polymerase II transcription factor activity, sequence-specific DNA binding);GO:0005654(nucleoplasm)","NA","NA","NA","zinc finger BED-type containing 5 [Source:HGNC Symbol;Acc:HGNC:30803]",{"v":6.963608,"d":"6.96"},{"v":0.437402,"d":"0.44"},{"v":15.9203844518315,"d":"15.92"},{"v":3.99280326996828,"d":"3.99"},{"v":6.80121424648447e-08,"d":"0.00"},{"v":6.75654955591054E-6,"d":"0.00"},"up","yes"]
[190065,"j","chr9","-",35697337,35727764,"MSTRG.14757.3",57,8240,"MSTRG.14757","TLN1","NA","NA","NA","NA","NA",{"v":3.689819,"d":"3.69"},{"v":60.078545,"d":"60.08"},{"v":0.0614165839069505,"d":"0.06"},{"v":-4.02522792033885,"d":"-4.03"},{"v":6.89902592745776e-08,"d":"0.00"},{"v":6.8197895900731e-06,"d":"0.00"},"down","yes"]
[62789,0,"chr15","-",55355250,55408510,"ENST00000310958",8,6822,"MSTRG.5103","CCPG1","GO:2001106(regulation of Rho guanyl-nucleotide exchange factor activity);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0007049(cell cycle);GO:0003674(molecular_function);GO:0008284(positive regulation of cell proliferation);GO:0005515(protein binding);GO:0045787(positive regulation of cell cycle);GO:0045944(positive regulation of transcription from RNA polymerase II promoter)","NA","NA","NA","cell cycle progression 1 [Source:HGNC Symbol;Acc:HGNC:24227]",{"v":0.304718,"d":"0.30"},{"v":5.118959,"d":"5.12"},{"v":0.0595273374918611,"d":"0.06"},{"v":-4.07030382208752,"d":"-4.07"},{"v":6.97891734663801e-08,"d":"0.00"},{"v":6.86477938806245e-06,"d":"0.00"},"down","yes"]
[26648,"j","chr11","-",10797014,10808983,"MSTRG.2259.1",22,4319,"MSTRG.2259","EIF4G2","NA","NA","NA","NA","NA",{"v":14.752528,"d":"14.75"},{"v":0.96683,"d":"0.97"},{"v":15.2586576750825,"d":"15.26"},{"v":3.93155614679241,"d":"3.93"},{"v":7.01745575170213E-8,"d":"0.00"},{"v":6.86885080637196e-06,"d":"0.00"},"up","yes"]
[132506,0,"chr22","-",50274979,50307572,"ENST00000359337",37,6335,"MSTRG.10594","PLXNB2","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0007165(signal transduction);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0007275(multicellular organism development);GO:0017154(semaphorin receptor activity);GO:0071526(semaphorin-plexin signaling pathway);GO:0005887(integral component of plasma membrane);GO:0070062(extracellular exosome);GO:0008360(regulation of cell shape);GO:0043087(regulation of GTPase activity);GO:0009986(cell surface);GO:0007405(neuroblast proliferation);GO:0007420(brain development);GO:0001843(neural tube closure);GO:0001932(regulation of protein phosphorylation);GO:0007156(homophilic cell adhesion via plasma membrane adhesion molecules);GO:0007162(negative regulation of cell adhesion);GO:0010976(positive regulation of neuron projection development);GO:0050772(positive regulation of axonogenesis);GO:2001222(regulation of neuron migration)","04360(Axon guidance)","K06821","NA","plexin B2 [Source:HGNC Symbol;Acc:HGNC:9104]",{"v":0.850504,"d":"0.85"},{"v":13.933985,"d":"13.93"},{"v":0.0610381021653174,"d":"0.06"},{"v":-4.03414608407755,"d":"-4.03"},{"v":7.28840356224248e-08,"d":"0.00"},{"v":7.06981842442878e-06,"d":"0.00"},"down","yes"]
[44783,0,"chr12","-",79797234,79935130,"ENST00000547330",15,2275,"MSTRG.3572","PPP1R12A","GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0015629(actin cytoskeleton);GO:0005515(protein binding);GO:0019901(protein kinase binding);GO:0005925(focal adhesion);GO:0007165(signal transduction);GO:0005813(centrosome);GO:0000776(kinetochore);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0005654(nucleoplasm);GO:0000086(G2/M transition of mitotic cell cycle);GO:0043292(contractile fiber);GO:0007098(centrosome cycle);GO:0004871(signal transducer activity);GO:0030155(regulation of cell adhesion);GO:0030018(Z disc);GO:0006470(protein dephosphorylation);GO:0000278(mitotic cell cycle);GO:0004857(enzyme inhibitor activity);GO:0019208(phosphatase regulator activity);GO:0071889(14-3-3 protein binding);GO:0035507(regulation of myosin-light-chain-phosphatase activity);GO:0035508(positive regulation of myosin-light-chain-phosphatase activity);GO:0035690(cellular response to drug);GO:0043086(negative regulation of catalytic activity);GO:0046822(regulation of nucleocytoplasmic transport);GO:0031672(A band);GO:0072357(PTW/PP1 phosphatase complex)","04024(cAMP signaling pathway);04022(cGMP - PKG signaling pathway);04510(Focal adhesion);04810(Regulation of actin cytoskeleton);04611(Platelet activation);04921(Oxytocin signaling pathway);04270(Vascular smooth muscle contraction);05205(Proteoglycans in cancer)","NA","NA","protein phosphatase 1 regulatory subunit 12A [Source:HGNC Symbol;Acc:HGNC:7618]",{"v":5.593178,"d":"5.59"},{"v":0.348736,"d":"0.35"},{"v":16.0384302165535,"d":"16.04"},{"v":4.00346103782601,"d":"4.00"},{"v":7.34795297322479e-08,"d":"0.00"},{"v":7.06981842442878e-06,"d":"0.00"},"up","yes"]
[160648,"j","chr5","-",160401727,160417206,"MSTRG.12519.2",16,3430,"MSTRG.12519","SLU7","NA","NA","NA","NA","NA",{"v":0.220605,"d":"0.22"},{"v":3.863032,"d":"3.86"},{"v":0.0571066975370641,"d":"0.06"},{"v":-4.13019623338325,"d":"-4.13"},{"v":7.34795297322479e-08,"d":"0.00"},{"v":7.06981842442878e-06,"d":"0.00"},"down","yes"]
[111347,0,"chr2","-",74526645,74529760,"ENST00000425118",12,1581,"MSTRG.8842","AUP1","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0050790(regulation of catalytic activity);GO:0005515(protein binding);GO:0030970(retrograde protein transport, ER to cytosol);GO:0070062(extracellular exosome);GO:0030176(integral component of endoplasmic reticulum membrane);GO:0043130(ubiquitin binding);GO:0030433(ubiquitin-dependent ERAD pathway);GO:0097027(ubiquitin-protein transferase activator activity);GO:0000839(Hrd1p ubiquitin ligase ERAD-L complex)","NA","NA","NA","ancient ubiquitous protein 1 [Source:HGNC Symbol;Acc:HGNC:891]",{"v":0.545239,"d":"0.55"},{"v":9.584608,"d":"9.58"},{"v":0.0568869378904176,"d":"0.06"},{"v":-4.13575876402777,"d":"-4.14"},{"v":7.36439419211331e-08,"d":"0.00"},{"v":7.06981842442878e-06,"d":"0.00"},"down","yes"]
[84192,0,"chr17","+",44350539,44353043,"ENST00000586443",7,1557,"MSTRG.6899","GRN","GO:0003723(RNA binding);GO:0005783(endoplasmic reticulum);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0005125(cytokine activity);GO:0005615(extracellular space);GO:0005764(lysosome);GO:0005768(endosome);GO:0070062(extracellular exosome);GO:0043312(neutrophil degranulation);GO:0007165(signal transduction);GO:0035578(azurophil granule lumen);GO:0008083(growth factor activity)","NA","NA","NA","granulin precursor [Source:HGNC Symbol;Acc:HGNC:4601]",{"v":18.16012,"d":"18.16"},{"v":1.191037,"d":"1.19"},{"v":15.2473180933926,"d":"15.25"},{"v":3.93048359896457,"d":"3.93"},{"v":8.06532949351773e-08,"d":"0.00"},{"v":7.67540528148869e-06,"d":"0.00"},"up","yes"]
[197800,0,"chrX","-",63426560,63561049,"ENST00000609143",3,2768,"ENSG00000235437","LINC01278","NA","NA","NA","NA","long intergenic non-protein coding RNA 1278 [Source:HGNC Symbol;Acc:HGNC:28090]",{"v":4.153264,"d":"4.15"},{"v":0.257236,"d":"0.26"},{"v":16.1457338786173,"d":"16.15"},{"v":4.01308111273484,"d":"4.01"},{"v":8.10552022031094e-08,"d":"0.00"},{"v":7.67540528148869e-06,"d":"0.00"},"up","yes"]
[62669,0,"chr15","-",52307283,52529050,"ENST00000399231",41,12225,"ENSG00000197535","MYO5A","GO:0003723(RNA binding);GO:0006810(transport);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0015031(protein transport);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0003774(motor activity);GO:0016459(myosin complex);GO:0003779(actin binding);GO:0005829(cytosol);GO:0005783(endoplasmic reticulum);GO:0005764(lysosome);GO:0005777(peroxisome);GO:0016192(vesicle-mediated transport);GO:0005516(calmodulin binding);GO:0030426(growth cone);GO:0070062(extracellular exosome);GO:0005769(early endosome);GO:0005770(late endosome);GO:0055037(recycling endosome);GO:0001726(ruffle);GO:0043005(neuron projection);GO:0031982(vesicle);GO:0032869(cellular response to insulin stimulus);GO:0005884(actin filament);GO:0017137(Rab GTPase binding);GO:0030050(vesicle transport along actin filament);GO:0000146(microfilament motor activity);GO:0006892(post-Golgi vesicle-mediated transport);GO:0030048(actin filament-based movement);GO:0072659(protein localization to plasma membrane);GO:0032433(filopodium tip);GO:0032593(insulin-responsive compartment);GO:0005509(calcium ion binding);GO:0097718(disordered domain specific binding);GO:0006582(melanin metabolic process);GO:0006887(exocytosis);GO:0007268(chemical synaptic transmission);GO:0007601(visual perception);GO:0030073(insulin secretion);GO:0030318(melanocyte differentiation);GO:0031585(regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity);GO:0031987(locomotion involved in locomotory behavior);GO:0032252(secretory granule localization);GO:0032400(melanosome localization);GO:0032402(melanosome transport);GO:0042438(melanin biosynthetic process);GO:0042476(odontogenesis);GO:0042552(myelination);GO:0042759(long-chain fatty acid biosynthetic process);GO:0043473(pigmentation);GO:0048066(developmental pigmentation);GO:0048820(hair follicle maturation);GO:0050808(synapse organization);GO:0051643(endoplasmic reticulum localization);GO:0001750(photoreceptor outer segment);GO:0005794(Golgi apparatus);GO:0005882(intermediate filament);GO:0016461(unconventional myosin complex);GO:0030141(secretory granule);GO:0035371(microtubule plus-end);GO:0042470(melanosome);GO:0042641(actomyosin);GO:0043025(neuronal cell body);GO:0051015(actin filament binding)","NA","NA","NA","myosin VA [Source:HGNC Symbol;Acc:HGNC:7602]",{"v":0.135433,"d":"0.14"},{"v":2.249758,"d":"2.25"},{"v":0.0601989191726399,"d":"0.06"},{"v":-4.0541186050866,"d":"-4.05"},{"v":8.11052941904103e-08,"d":"0.00"},{"v":7.67540528148869e-06,"d":"0.00"},"down","yes"]
[98973,0,"chr19","-",19645203,19655451,"ENST00000497556",15,2442,"MSTRG.8026","ATP13A1","GO:0003674(molecular_function);GO:0008150(biological_process);GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0016787(hydrolase activity);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0006812(cation transport);GO:0099132(ATP hydrolysis coupled cation transmembrane transport);GO:0071421(manganese ion transmembrane transport);GO:0070588(calcium ion transmembrane transport);GO:0016887(ATPase activity);GO:0005887(integral component of plasma membrane);GO:0034220(ion transmembrane transport);GO:0006874(cellular calcium ion homeostasis);GO:0043231(intracellular membrane-bounded organelle);GO:0005388(calcium-transporting ATPase activity);GO:0015410(manganese-transporting ATPase activity)","NA","NA","NA","ATPase 13A1 [Source:HGNC Symbol;Acc:HGNC:24215]",{"v":4.54219,"d":"4.54"},{"v":0.280801,"d":"0.28"},{"v":16.1758327071485,"d":"16.18"},{"v":4.01576807675284,"d":"4.02"},{"v":8.35966224152416e-08,"d":"0.00"},{"v":7.87385545465823e-06,"d":"0.00"},"up","yes"]
[117038,0,"chr2","+",181891955,181930738,"ENST00000320370",17,4965,"MSTRG.9290","SSFA2","GO:0005737(cytoplasm);GO:0005634(nucleus);GO:0005829(cytosol);GO:0003779(actin binding);GO:0005886(plasma membrane);GO:0005102(receptor binding);GO:0051015(actin filament binding)","NA","NA","NA","sperm specific antigen 2 [Source:HGNC Symbol;Acc:HGNC:11319]",{"v":0.20203,"d":"0.20"},{"v":3.449163,"d":"3.45"},{"v":0.0585736307620139,"d":"0.06"},{"v":-4.09360486524356,"d":"-4.09"},{"v":8.75281030504031e-08,"d":"0.00"},{"v":8.20545146342934e-06,"d":"0.00"},"down","yes"]
[183966,0,"chr8","-",56073316,56074498,"ENST00000518875",3,671,"MSTRG.14365","RPS20","GO:0003723(RNA binding);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0006412(translation);GO:0030529(intracellular ribonucleoprotein complex);GO:0005622(intracellular);GO:0003735(structural constituent of ribosome);GO:0005840(ribosome);GO:0015935(small ribosomal subunit);GO:0005515(protein binding);GO:0022627(cytosolic small ribosomal subunit);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0031012(extracellular matrix);GO:0002181(cytoplasmic translation);GO:0006413(translational initiation);GO:0006364(rRNA processing);GO:0000184(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay);GO:0019083(viral transcription);GO:0006614(SRP-dependent cotranslational protein targeting to membrane)","03010(Ribosome)","NA","NA","ribosomal protein S20 [Source:HGNC Symbol;Acc:HGNC:10405]",{"v":27.890942,"d":"27.89"},{"v":1.80234,"d":"1.80"},{"v":15.474850472164,"d":"15.47"},{"v":3.95185356415826,"d":"3.95"},{"v":9.14888650519732e-08,"d":"0.00"},{"v":8.53668064185888e-06,"d":"0.00"},"up","yes"]
[112118,"j","chr2","-",88846694,89100361,"MSTRG.8934.12",5,957,"MSTRG.8934","IGKV1-16","NA","NA","NA","NA","NA",{"v":56.647678,"d":"56.65"},{"v":3.865285,"d":"3.87"},{"v":14.6554983655798,"d":"14.66"},{"v":3.87337012312127,"d":"3.87"},{"v":1.01266410320614e-07,"d":"0.00"},{"v":9.40505898270709e-06,"d":"0.00"},"up","yes"]
[156340,"j","chr5","-",82273320,82278419,"MSTRG.12175.1",5,3210,"MSTRG.12175","RPS23","NA","NA","NA","NA","NA",{"v":34.276737,"d":"34.28"},{"v":2.370536,"d":"2.37"},{"v":14.4594880651464,"d":"14.46"},{"v":3.85394456979405,"d":"3.85"},{"v":1.05300317833061E-7,"d":"0.00"},{"v":9.73442938190077e-06,"d":"0.00"},"up","yes"]
[48182,0,"chr12","-",124324415,124535603,"ENST00000404621",47,8520,"ENSG00000196498","NCOR2","GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0003677(DNA binding);GO:0001012(RNA polymerase II regulatory region DNA binding);GO:0003682(chromatin binding);GO:0016922(ligand-dependent nuclear receptor binding);GO:0032403(protein complex binding);GO:0035259(glucocorticoid receptor binding);GO:0042974(retinoic acid receptor binding);GO:0046965(retinoid X receptor binding);GO:0007595(lactation);GO:0010243(response to organonitrogen compound);GO:0032355(response to estradiol);GO:0044849(estrous cycle);GO:0000785(chromatin);GO:0016020(membrane);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0005515(protein binding);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0003714(transcription corepressor activity);GO:0008134(transcription factor binding);GO:0047485(protein N-terminus binding);GO:0000790(nuclear chromatin);GO:0016363(nuclear matrix);GO:0005112(Notch binding);GO:0042826(histone deacetylase binding);GO:0019216(regulation of lipid metabolic process);GO:0017053(transcriptional repressor complex);GO:1903799(negative regulation of production of miRNAs involved in gene silencing by miRNA);GO:0000118(histone deacetylase complex);GO:0072365(regulation of cellular ketone metabolic process by negative regulation of transcription from RNA polymerase II promoter);GO:0016604(nuclear body)","04330(Notch signaling pathway);05169(Epstein-Barr virus infection)","K06065","NA","nuclear receptor corepressor 2 [Source:HGNC Symbol;Acc:HGNC:7673]",{"v":0.218903,"d":"0.22"},{"v":3.517237,"d":"3.52"},{"v":0.0622372049424022,"d":"0.06"},{"v":-4.00607891907596,"d":"-4.01"},{"v":1.07075744321389e-07,"d":"0.00"},{"v":9.85294222400688e-06,"d":"0.00"},"down","yes"]
[65601,0,"chr15","+",81296913,81309083,"ENST00000394652",7,2397,"MSTRG.5358","IL16","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016607(nuclear speck);GO:0005829(cytosol);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0005886(plasma membrane);GO:0005576(extracellular region);GO:0005125(cytokine activity);GO:0005615(extracellular space);GO:0006935(chemotaxis);GO:0016032(viral process);GO:0006955(immune response);GO:0051924(regulation of calcium ion transport);GO:0042609(CD4 receptor binding);GO:0030595(leukocyte chemotaxis);GO:0050930(induction of positive chemotaxis);GO:0005622(intracellular)","NA","NA","NA","interleukin 16 [Source:HGNC Symbol;Acc:HGNC:5980]",{"v":1.596279,"d":"1.60"},{"v":25.082592,"d":"25.08"},{"v":0.0636409107958221,"d":"0.06"},{"v":-3.97390170685226,"d":"-3.97"},{"v":1.09519963959186E-7,"d":"0.00"},{"v":1.00316267905368E-5,"d":"0.00"},"down","yes"]
[85002,0,"chr17","-",48070052,48101198,"ENST00000393408",5,2422,"MSTRG.6957","CBX1","GO:0005634(nucleus);GO:0005515(protein binding);GO:0005819(spindle);GO:0000775(chromosome, centromeric region);GO:0000784(nuclear chromosome, telomeric region);GO:0019899(enzyme binding);GO:0000785(chromatin);GO:0005654(nucleoplasm);GO:0003682(chromatin binding);GO:0005720(nuclear heterochromatin);GO:0042802(identical protein binding);GO:0042803(protein homodimerization activity);GO:1990226(histone methyltransferase binding);GO:0045892(negative regulation of transcription, DNA-templated);GO:0001939(female pronucleus);GO:0001940(male pronucleus);GO:0005721(pericentric heterochromatin);GO:0010369(chromocenter)","NA","NA","NA","chromobox 1 [Source:HGNC Symbol;Acc:HGNC:1551]",{"v":4.556105,"d":"4.56"},{"v":0.29329,"d":"0.29"},{"v":15.5344710013979,"d":"15.53"},{"v":3.9574012087865,"d":"3.96"},{"v":1.16491915257688e-07,"d":"0.00"},{"v":1.06215094240435E-5,"d":"0.00"},"up","yes"]
[121778,0,"chr20","-",4780023,4823645,"ENST00000379400",12,5427,"MSTRG.9583","RASSF2","GO:0005737(cytoplasm);GO:0005634(nucleus);GO:0005794(Golgi apparatus);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0007165(signal transduction);GO:0042981(regulation of apoptotic process);GO:0006468(protein phosphorylation);GO:0005694(chromosome);GO:0005515(protein binding);GO:0007049(cell cycle);GO:0000775(chromosome, centromeric region);GO:0000776(kinetochore);GO:0000777(condensed chromosome kinetochore);GO:0043234(protein complex);GO:0050821(protein stabilization);GO:0004672(protein kinase activity);GO:0043065(positive regulation of apoptotic process);GO:0045860(positive regulation of protein kinase activity);GO:0001501(skeletal system development);GO:0001503(ossification);GO:0031954(positive regulation of protein autophosphorylation);GO:0033137(negative regulation of peptidyl-serine phosphorylation);GO:0038168(epidermal growth factor receptor signaling pathway via I-kappaB kinase/NF-kappaB cascade);GO:0045667(regulation of osteoblast differentiation);GO:0045670(regulation of osteoclast differentiation);GO:0046330(positive regulation of JNK cascade);GO:0046849(bone remodeling);GO:0048872(homeostasis of number of cells);GO:1901222(regulation of NIK/NF-kappaB signaling);GO:1901223(negative regulation of NIK/NF-kappaB signaling)","04392(Hippo signaling pathway - multiple species)","K09851","NA","Ras association domain family member 2 [Source:HGNC Symbol;Acc:HGNC:9883]",{"v":1.464263,"d":"1.46"},{"v":22.520788,"d":"22.52"},{"v":0.0650182844401359,"d":"0.07"},{"v":-3.94301069991626,"d":"-3.94"},{"v":1.23477611183969E-7,"d":"0.00"},{"v":1.12072770005522E-5,"d":"0.00"},"down","yes"]
[160944,0,"chr5","+",169761307,170083377,"ENST00000523351",28,3777,"MSTRG.12528","DOCK2","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0007264(small GTPase mediated signal transduction);GO:0043547(positive regulation of GTPase activity);GO:0030036(actin cytoskeleton organization);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0005085(guanyl-nucleotide exchange factor activity);GO:0005576(extracellular region);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0012505(endomembrane system);GO:0043312(neutrophil degranulation);GO:0050766(positive regulation of phagocytosis);GO:0035580(specific granule lumen);GO:0050690(regulation of defense response to virus by virus);GO:0030676(Rac guanyl-nucleotide exchange factor activity);GO:0042608(T cell receptor binding);GO:0044351(macropinocytosis);GO:0002277(myeloid dendritic cell activation involved in immune response);GO:0005096(GTPase activator activity);GO:0001766(membrane raft polarization);GO:0001768(establishment of T cell polarity);GO:0001771(immunological synapse formation);GO:0006935(chemotaxis);GO:0007010(cytoskeleton organization);GO:0042098(T cell proliferation);GO:0042110(T cell activation);GO:0045059(positive thymic T cell selection);GO:0045060(negative thymic T cell selection);GO:0046631(alpha-beta T cell activation);GO:0046633(alpha-beta T cell proliferation);GO:0005622(intracellular)","04666(Fc gamma R-mediated phagocytosis);04062(Chemokine signaling pathway)","NA","NA","dedicator of cytokinesis 2 [Source:HGNC Symbol;Acc:HGNC:2988]",{"v":9.280781,"d":"9.28"},{"v":0.644084,"d":"0.64"},{"v":14.4092711509679,"d":"14.41"},{"v":3.84892545791721,"d":"3.85"},{"v":1.2535895709557e-07,"d":"0.00"},{"v":1.13265504763997e-05,"d":"0.00"},"up","yes"]
[98640,0,"chr19","+",18557788,18569378,"ENST00000222307",5,1426,"MSTRG.8000","KXD1","GO:0016020(membrane);GO:0005765(lysosomal membrane);GO:0005515(protein binding);GO:0005764(lysosome);GO:0016192(vesicle-mediated transport);GO:0032418(lysosome localization);GO:0031083(BLOC-1 complex);GO:0099078(BORC complex)","NA","NA","NA","KxDL motif containing 1 [Source:HGNC Symbol;Acc:HGNC:28420]",{"v":1.119627,"d":"1.12"},{"v":17.813442,"d":"17.81"},{"v":0.0628529287040652,"d":"0.06"},{"v":-3.99187621953801,"d":"-3.99"},{"v":1.27828526993076e-07,"d":"0.00"},{"v":1.14976577792691e-05,"d":"0.00"},"down","yes"]
[11129,0,"chr1","-",153543613,153545063,"ENST00000368715",3,573,"MSTRG.978","S100A4","GO:0003723(RNA binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0005509(calcium ion binding);GO:0005515(protein binding);GO:0048471(perinuclear region of cytoplasm);GO:0005615(extracellular space);GO:0046914(transition metal ion binding);GO:0070062(extracellular exosome);GO:0043123(positive regulation of I-kappaB kinase/NF-kappaB signaling);GO:0050786(RAGE receptor binding);GO:0001837(epithelial to mesenchymal transition);GO:0003779(actin binding);GO:0042802(identical protein binding);GO:0048306(calcium-dependent protein binding);GO:0043005(neuron projection)","NA","NA","NA","S100 calcium binding protein A4 [Source:HGNC Symbol;Acc:HGNC:10494]",{"v":23.183958,"d":"23.18"},{"v":1.551593,"d":"1.55"},{"v":14.9420357013727,"d":"14.94"},{"v":3.90130480902555,"d":"3.90"},{"v":1.33503796672031e-07,"d":"0.00"},{"v":1.19542771836193E-5,"d":"0.00"},"up","yes"]
[38103,0,"chr12","+",6867420,6870946,"ENST00000613953",7,1460,"MSTRG.3075","TPI1","GO:0005634(nucleus);GO:0016853(isomerase activity);GO:0003824(catalytic activity);GO:0006096(glycolytic process);GO:0008152(metabolic process);GO:0005515(protein binding);GO:0005615(extracellular space);GO:0006094(gluconeogenesis);GO:0006098(pentose-phosphate shunt);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0061621(canonical glycolysis);GO:0031625(ubiquitin protein ligase binding);GO:0004807(triose-phosphate isomerase activity);GO:0006006(glucose metabolic process);GO:0007275(multicellular organism development);GO:0019563(glycerol catabolic process);GO:0019682(glyceraldehyde-3-phosphate metabolic process);GO:0046166(glyceraldehyde-3-phosphate biosynthetic process)","00010(Glycolysis / Gluconeogenesis);00051(Fructose and mannose metabolism);00562(Inositol phosphate metabolism)","K01803","EC:5.3.1.1","triosephosphate isomerase 1 [Source:HGNC Symbol;Acc:HGNC:12009]",{"v":2.018389,"d":"2.02"},{"v":31.020767,"d":"31.02"},{"v":0.0650657348349897,"d":"0.07"},{"v":-3.94195820395617,"d":"-3.94"},{"v":1.39885787627709e-07,"d":"0.00"},{"v":1.24698187828129e-05,"d":"0.00"},"down","yes"]
[71769,0,"chr16","-",30092314,30096200,"ENST00000398841",4,1588,"MSTRG.5823","YPEL3","GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0005730(nucleolus);GO:2000774(positive regulation of cellular senescence)","NA","NA","NA","yippee like 3 [Source:HGNC Symbol;Acc:HGNC:18327]",{"v":2.167544,"d":"2.17"},{"v":33.098984,"d":"33.10"},{"v":0.065486723096999,"d":"0.07"},{"v":-3.93265374821928,"d":"-3.93"},{"v":1.40675299152631E-7,"d":"0.00"},{"v":1.24844638821322E-5,"d":"0.00"},"down","yes"]
[165679,0,"chr6","+",36885854,36928964,"ENST00000480824",9,6861,"MSTRG.12999","C6orf89","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005794(Golgi apparatus);GO:0005886(plasma membrane);GO:0000139(Golgi membrane);GO:0005730(nucleolus);GO:0030496(midbody);GO:0005515(protein binding);GO:0042060(wound healing);GO:0045787(positive regulation of cell cycle);GO:0050673(epithelial cell proliferation);GO:1901727(positive regulation of histone deacetylase activity)","NA","NA","NA","chromosome 6 open reading frame 89 [Source:HGNC Symbol;Acc:HGNC:21114]",{"v":0.088493,"d":"0.09"},{"v":1.477538,"d":"1.48"},{"v":0.0598921990500414,"d":"0.06"},{"v":-4.06148808533711,"d":"-4.06"},{"v":1.44670784684626E-7,"d":"0.00"},{"v":1.27822399494806e-05,"d":"0.00"},"down","yes"]
[23194,"j","chr10","-",103088017,103181329,"MSTRG.1950.1",18,3510,"MSTRG.1950","NT5C2","NA","NA","NA","NA","NA",{"v":0.536846,"d":"0.54"},{"v":8.292802,"d":"8.29"},{"v":0.0647363822264176,"d":"0.06"},{"v":-3.94927944656073,"d":"-3.95"},{"v":1.46308768106789e-07,"d":"0.00"},{"v":1.28700153372527E-5,"d":"0.00"},"down","yes"]
[112057,0,"chr2","-",88027205,88055729,"ENST00000347055",4,1753,"MSTRG.8903","KRCC1","GO:0005622(intracellular);GO:0003723(RNA binding);GO:0002039(p53 binding);GO:0072332(intrinsic apoptotic signaling pathway by p53 class mediator)","NA","NA","NA","lysine rich coiled-coil 1 [Source:HGNC Symbol;Acc:HGNC:28039]",{"v":0.76578,"d":"0.77"},{"v":11.992533,"d":"11.99"},{"v":0.0638547336079876,"d":"0.06"},{"v":-3.96906261762061,"d":"-3.97"},{"v":1.52261000246237e-07,"d":"0.00"},{"v":1.33348581268283E-5,"d":"0.00"},"down","yes"]
[84864,0,"chr17","-",47826895,47831523,"ENST00000466016",3,544,"MSTRG.6954","MRPL10","GO:0003723(RNA binding);GO:0006412(translation);GO:0005654(nucleoplasm);GO:0005739(mitochondrion);GO:0030529(intracellular ribonucleoprotein complex);GO:0005622(intracellular);GO:0005840(ribosome);GO:0005515(protein binding);GO:0003735(structural constituent of ribosome);GO:0042254(ribosome biogenesis);GO:0032543(mitochondrial translation);GO:0005743(mitochondrial inner membrane);GO:0070125(mitochondrial translational elongation);GO:0070126(mitochondrial translational termination);GO:0005762(mitochondrial large ribosomal subunit)","03010(Ribosome)","NA","NA","mitochondrial ribosomal protein L10 [Source:HGNC Symbol;Acc:HGNC:14055]",{"v":29.904833,"d":"29.90"},{"v":2.07738,"d":"2.08"},{"v":14.3954562959112,"d":"14.40"},{"v":3.84754161393217,"d":"3.85"},{"v":1.71211179783579e-07,"d":"0.00"},{"v":1.49290167594695e-05,"d":"0.00"},"up","yes"]
[54901,0,"chr14","-",50725833,50831121,"ENST00000324330",29,4364,"MSTRG.4381","NIN","GO:0005509(calcium ion binding);GO:0005813(centrosome);GO:0034454(microtubule anchoring at centrosome);GO:0005737(cytoplasm);GO:0000166(nucleotide binding);GO:0005634(nucleus);GO:0005730(nucleolus);GO:0005525(GTP binding);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0005874(microtubule);GO:0005815(microtubule organizing center);GO:0005814(centriole);GO:0097539(ciliary transition fiber);GO:0000922(spindle pole);GO:0000242(pericentriolar material);GO:0051642(centrosome localization);GO:0090222(centrosome-templated microtubule nucleation);GO:0036449(microtubule minus-end);GO:0097431(mitotic spindle pole)","NA","NA","NA","ninein [Source:HGNC Symbol;Acc:HGNC:14906]",{"v":2.296788,"d":"2.30"},{"v":0.155655,"d":"0.16"},{"v":14.7556326491279,"d":"14.76"},{"v":3.88319387266797,"d":"3.88"},{"v":1.77964842685788E-7,"d":"0.00"},{"v":1.53853983793159E-5,"d":"0.00"},"up","yes"]
[12489,"j","chr1","+",159800523,159816424,"MSTRG.1106.5",10,2128,"MSTRG.1106","FCRL6","NA","NA","NA","NA","NA",{"v":0.628983,"d":"0.63"},{"v":9.704043,"d":"9.70"},{"v":0.0648165924244153,"d":"0.06"},{"v":-3.94749301332787,"d":"-3.95"},{"v":1.77986129087638e-07,"d":"0.00"},{"v":1.53853983793159E-5,"d":"0.00"},"down","yes"]
[14597,0,"chr1","+",198156963,198322420,"ENST00000367385",10,4149,"MSTRG.1271","NEK7","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0005654(nucleoplasm);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0005856(cytoskeleton);GO:0005874(microtubule);GO:0000922(spindle pole);GO:0005815(microtubule organizing center);GO:0007346(regulation of mitotic cell cycle);GO:0000910(cytokinesis);GO:0032212(positive regulation of telomere maintenance via telomerase);GO:0051973(positive regulation of telomerase activity);GO:1904355(positive regulation of telomere capping);GO:0051225(spindle assembly)","04621(NOD-like receptor signaling pathway)","K20876","EC:2.7.11.1","NIMA related kinase 7 [Source:HGNC Symbol;Acc:HGNC:13386]",{"v":1.065572,"d":"1.07"},{"v":15.811078,"d":"15.81"},{"v":0.0673940132355302,"d":"0.07"},{"v":-3.89123575057866,"d":"-3.89"},{"v":1.81649011420887e-07,"d":"0.00"},{"v":1.56343425002253e-05,"d":"0.00"},"down","yes"]
[54902,0,"chr14","-",50725840,50831121,"ENST00000382041",30,6496,"MSTRG.4381","NIN","GO:0005509(calcium ion binding);GO:0005813(centrosome);GO:0034454(microtubule anchoring at centrosome);GO:0005737(cytoplasm);GO:0000166(nucleotide binding);GO:0005634(nucleus);GO:0005730(nucleolus);GO:0005525(GTP binding);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0005874(microtubule);GO:0005815(microtubule organizing center);GO:0005814(centriole);GO:0097539(ciliary transition fiber);GO:0000922(spindle pole);GO:0000242(pericentriolar material);GO:0051642(centrosome localization);GO:0090222(centrosome-templated microtubule nucleation);GO:0036449(microtubule minus-end);GO:0097431(mitotic spindle pole)","NA","NA","NA","ninein [Source:HGNC Symbol;Acc:HGNC:14906]",{"v":3.564037,"d":"3.56"},{"v":0.255209,"d":"0.26"},{"v":13.9651697236383,"d":"13.97"},{"v":3.80376120219397,"d":"3.80"},{"v":1.92030969962257e-07,"d":"0.00"},{"v":1.64569717090401e-05,"d":"0.00"},"up","yes"]
[38796,0,"chr12","+",10212805,10223130,"ENST00000266458",4,1957,"MSTRG.3164","GABARAPL1","GO:0006914(autophagy);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005794(Golgi apparatus);GO:0005783(endoplasmic reticulum);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0005874(microtubule);GO:0030659(cytoplasmic vesicle membrane);GO:0031410(cytoplasmic vesicle);GO:0032590(dendrite membrane);GO:0032839(dendrite cytoplasm);GO:0044297(cell body);GO:0005829(cytosol);GO:0000045(autophagosome assembly);GO:0000422(mitophagy);GO:0006995(cellular response to nitrogen starvation);GO:0000421(autophagosome membrane);GO:0031625(ubiquitin protein ligase binding);GO:0005776(autophagosome);GO:0005739(mitochondrion);GO:0030957(Tat protein binding);GO:0048487(beta-tubulin binding);GO:0005622(intracellular);GO:0016236(macroautophagy);GO:0050811(GABA receptor binding);GO:0097352(autophagosome maturation)","04371(Apelin signaling pathway);04068(FoxO signaling pathway);04140(Autophagy - animal);04136(Autophagy - other eukaryotes);04137(Mitophagy - animal);04621(NOD-like receptor signaling pathway);04727(GABAergic synapse);05167(Kaposi's sarcoma-associated herpesvirus infection)","K08341","NA","GABA type A receptor associated protein like 1 [Source:HGNC Symbol;Acc:HGNC:4068]",{"v":1.962172,"d":"1.96"},{"v":28.88685,"d":"28.89"},{"v":0.0679261324789653,"d":"0.07"},{"v":-3.8798894762076,"d":"-3.88"},{"v":1.93657017660149E-7,"d":"0.00"},{"v":1.65253988403327E-5,"d":"0.00"},"down","yes"]
[181931,0,"chr8","+",22059348,22082518,"ENST00000415253",15,2394,"MSTRG.14210","DMTN","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0003779(actin binding);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0051693(actin filament capping);GO:0005856(cytoskeleton);GO:0042995(cell projection);GO:0005515(protein binding);GO:0048471(perinuclear region of cytoplasm);GO:0031410(cytoplasmic vesicle);GO:0007010(cytoskeleton organization);GO:0032956(regulation of actin cytoskeleton organization);GO:0055085(transmembrane transport);GO:0012505(endomembrane system);GO:0005102(receptor binding);GO:0008360(regulation of cell shape);GO:0051017(actin filament bundle assembly);GO:0030036(actin cytoskeleton organization);GO:0005884(actin filament);GO:0051895(negative regulation of focal adhesion assembly);GO:0090315(negative regulation of protein targeting to membrane);GO:1900025(negative regulation of substrate adhesion-dependent cell spreading);GO:0006461(protein complex assembly);GO:0015629(actin cytoskeleton);GO:0071320(cellular response to cAMP);GO:0071277(cellular response to calcium ion);GO:0035584(calcium-mediated signaling using intracellular calcium source);GO:0051489(regulation of filopodium assembly);GO:1900026(positive regulation of substrate adhesion-dependent cell spreading);GO:0090303(positive regulation of wound healing);GO:0090527(actin filament reorganization);GO:2001046(positive regulation of integrin-mediated signaling pathway);GO:0033137(negative regulation of peptidyl-serine phosphorylation);GO:0030507(spectrin binding);GO:0010591(regulation of lamellipodium assembly);GO:0048821(erythrocyte development);GO:0010763(positive regulation of fibroblast migration);GO:0010801(negative regulation of peptidyl-threonine phosphorylation);GO:0010812(negative regulation of cell-substrate adhesion);GO:0030194(positive regulation of blood coagulation);GO:0035585(calcium-mediated signaling using extracellular calcium source);GO:0050732(negative regulation of peptidyl-tyrosine phosphorylation);GO:0070560(protein secretion by platelet);GO:1901731(positive regulation of platelet aggregation);GO:0014731(spectrin-associated cytoskeleton);GO:0031095(platelet dense tubular network membrane);GO:0031253(cell projection membrane);GO:0043621(protein self-association);GO:0014069(postsynaptic density);GO:0030863(cortical cytoskeleton)","NA","NA","NA","dematin actin binding protein [Source:HGNC Symbol;Acc:HGNC:3382]",{"v":18.960369,"d":"18.96"},{"v":1.391344,"d":"1.39"},{"v":13.6273768385101,"d":"13.63"},{"v":3.76843597645197,"d":"3.77"},{"v":1.94515808997364E-7,"d":"0.00"},{"v":1.65280496768483e-05,"d":"0.00"},"up","yes"]
[47976,0,"chr12","+",122980748,122982706,"ENST00000439686",6,796,"MSTRG.3844","ARL6IP4","GO:0003723(RNA binding);GO:0006397(mRNA processing);GO:0008380(RNA splicing);GO:0005634(nucleus);GO:0016607(nuclear speck);GO:0005515(protein binding);GO:0005730(nucleolus)","NA","NA","NA","ADP ribosylation factor like GTPase 6 interacting protein 4 [Source:HGNC Symbol;Acc:HGNC:18076]",{"v":1.263681,"d":"1.26"},{"v":19.636154,"d":"19.64"},{"v":0.0643548120472064,"d":"0.06"},{"v":-3.95780816165379,"d":"-3.96"},{"v":1.95524697354637e-07,"d":"0.00"},{"v":1.65383022745117e-05,"d":"0.00"},"down","yes"]
[10608,0,"chr1","-",150621251,150629596,"ENST00000369014",4,2085,"MSTRG.921","ENSA","GO:0005737(cytoplasm);GO:0051301(cell division);GO:0050790(regulation of catalytic activity);GO:0005515(protein binding);GO:0043086(negative regulation of catalytic activity);GO:0007049(cell cycle);GO:0065009(regulation of molecular function);GO:0004864(protein phosphatase inhibitor activity);GO:0005654(nucleoplasm);GO:0006810(transport);GO:0005102(receptor binding);GO:0000278(mitotic cell cycle);GO:0007584(response to nutrient);GO:0008200(ion channel inhibitor activity);GO:0019212(phosphatase inhibitor activity);GO:0019870(potassium channel inhibitor activity);GO:0019888(protein phosphatase regulator activity);GO:0051721(protein phosphatase 2A binding);GO:0000086(G2/M transition of mitotic cell cycle);GO:0035308(negative regulation of protein dephosphorylation);GO:0050796(regulation of insulin secretion);GO:0009749(response to glucose)","NA","NA","NA","endosulfine alpha [Source:HGNC Symbol;Acc:HGNC:3360]",{"v":0.716542,"d":"0.72"},{"v":10.868216,"d":"10.87"},{"v":0.065930047764969,"d":"0.07"},{"v":-3.92292006321158,"d":"-3.92"},{"v":1.96292950674043e-07,"d":"0.00"},{"v":1.65383022745117e-05,"d":"0.00"},"down","yes"]
[169884,"j","chr6","+",144659374,144852732,"MSTRG.13329.7",24,5421,"MSTRG.13329","UTRN","NA","NA","NA","NA","NA",{"v":0.144039,"d":"0.14"},{"v":2.239522,"d":"2.24"},{"v":0.0643168497563319,"d":"0.06"},{"v":-3.95865944482845,"d":"-3.96"},{"v":2.02491780704653e-07,"d":"0.00"},{"v":1.69888902399601e-05,"d":"0.00"},"down","yes"]
[73492,0,"chr16","-",57249039,57284661,"ENST00000613167",4,7578,"MSTRG.5953","PLLP","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0006810(transport);GO:0006811(ion transport);GO:0005515(protein binding);GO:0009611(response to wounding);GO:0042552(myelination);GO:0043218(compact myelin);GO:0045121(membrane raft);GO:0070062(extracellular exosome);GO:0008104(protein localization);GO:0019911(structural constituent of myelin sheath);GO:0001766(membrane raft polarization)","NA","NA","NA","plasmolipin [Source:HGNC Symbol;Acc:HGNC:18553]",{"v":2.296556,"d":"2.30"},{"v":0.164581,"d":"0.16"},{"v":13.9539558029177,"d":"13.95"},{"v":3.80260226412715,"d":"3.80"},{"v":2.04440645627729E-7,"d":"0.00"},{"v":1.70806310121109e-05,"d":"0.00"},"up","yes"]
[190175,0,"chr9","-",36336396,36400299,"ENST00000353739",11,4945,"ENSG00000137075","RNF38","GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0005654(nucleoplasm);GO:0016740(transferase activity);GO:0016567(protein ubiquitination);GO:0061630(ubiquitin protein ligase activity);GO:0043161(proteasome-mediated ubiquitin-dependent protein catabolic process);GO:0004842(ubiquitin-protein transferase activity);GO:0008584(male gonad development);GO:0036126(sperm flagellum)","NA","NA","NA","ring finger protein 38 [Source:HGNC Symbol;Acc:HGNC:18052]",{"v":0.416949,"d":"0.42"},{"v":6.190981,"d":"6.19"},{"v":0.0673478080452839,"d":"0.07"},{"v":-3.89222519841023,"d":"-3.89"},{"v":2.11856773212121e-07,"d":"0.00"},{"v":1.76264835312485e-05,"d":"0.00"},"down","yes"]
[3785,0,"chr1","+",32013996,32042624,"ENST00000492989",8,1215,"MSTRG.360","KHDRBS1","GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0006397(mRNA processing);GO:0005634(nucleus);GO:0016020(membrane);GO:0005654(nucleoplasm);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0009967(positive regulation of signal transduction);GO:0005515(protein binding);GO:0007049(cell cycle);GO:0042802(identical protein binding);GO:0045948(positive regulation of translational initiation);GO:0005829(cytosol);GO:0017124(SH3 domain binding);GO:0003677(DNA binding);GO:0007165(signal transduction);GO:0019904(protein domain specific binding);GO:0045892(negative regulation of transcription, DNA-templated);GO:0051259(protein oligomerization);GO:0008283(cell proliferation);GO:0007050(cell cycle arrest);GO:0000086(G2/M transition of mitotic cell cycle);GO:0005070(SH3/SH2 adaptor activity);GO:0007166(cell surface receptor signaling pathway);GO:0008143(poly(A) binding);GO:0008266(poly(U) RNA binding);GO:0046833(positive regulation of RNA export from nucleus);GO:0032403(protein complex binding);GO:0007283(spermatogenesis);GO:0046831(regulation of RNA export from nucleus);GO:0048024(regulation of mRNA splicing, via spliceosome);GO:0005737(cytoplasm);GO:0070618(Grb2-Sos complex)","NA","NA","NA","KH RNA binding domain containing, signal transduction associated 1 [Source:HGNC Symbol;Acc:HGNC:18116]",{"v":0.774246,"d":"0.77"},{"v":11.86835,"d":"11.87"},{"v":0.065236195427334,"d":"0.07"},{"v":-3.93818354319656,"d":"-3.94"},{"v":2.1632755356216e-07,"d":"0.00"},{"v":1.79237700810341e-05,"d":"0.00"},"down","yes"]
[98147,0,"chr19","+",17101718,17212099,"ENST00000595641",38,6215,"MSTRG.7951","MYO9B","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0005829(cytosol);GO:0035556(intracellular signal transduction);GO:0007165(signal transduction);GO:0003774(motor activity);GO:0016459(myosin complex);GO:0003779(actin binding);GO:0005856(cytoskeleton);GO:0005096(GTPase activator activity);GO:0048471(perinuclear region of cytoplasm);GO:0043547(positive regulation of GTPase activity);GO:0005516(calmodulin binding);GO:0005515(protein binding);GO:0051056(regulation of small GTPase mediated signal transduction);GO:0005938(cell cortex);GO:0016887(ATPase activity);GO:0015629(actin cytoskeleton);GO:0005884(actin filament);GO:0007266(Rho protein signal transduction);GO:0017048(Rho GTPase binding);GO:0048495(Roundabout binding);GO:0000146(microfilament motor activity);GO:0030048(actin filament-based movement);GO:0035023(regulation of Rho protein signal transduction);GO:0043531(ADP binding);GO:0035385(Roundabout signaling pathway);GO:0005622(intracellular)","NA","NA","NA","myosin IXB [Source:HGNC Symbol;Acc:HGNC:7609]",{"v":0.121392,"d":"0.12"},{"v":1.87908,"d":"1.88"},{"v":0.0646018264256977,"d":"0.06"},{"v":-3.95228123634085,"d":"-3.95"},{"v":2.2257429428979e-07,"d":"0.00"},{"v":1.83651384643741e-05,"d":"0.00"},"down","yes"]
[161892,0,"chr5","-",179614178,179623710,"ENST00000393432",14,2279,"MSTRG.12597","HNRNPH1","GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0006397(mRNA processing);GO:0008380(RNA splicing);GO:0005634(nucleus);GO:0016020(membrane);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0030529(intracellular ribonucleoprotein complex);GO:0005681(spliceosomal complex);GO:0005515(protein binding);GO:0043484(regulation of RNA splicing);GO:0000398(mRNA splicing, via spliceosome);GO:0008543(fibroblast growth factor receptor signaling pathway);GO:0016070(RNA metabolic process);GO:0006396(RNA processing);GO:0071013(catalytic step 2 spliceosome);GO:0008266(poly(U) RNA binding)","NA","NA","NA","heterogeneous nuclear ribonucleoprotein H1 [Source:HGNC Symbol;Acc:HGNC:5041]",{"v":25.42914,"d":"25.43"},{"v":1.914284,"d":"1.91"},{"v":13.2838910004994,"d":"13.28"},{"v":3.73160588501435,"d":"3.73"},{"v":2.30653067883598e-07,"d":"0.00"},{"v":1.89534175288052E-5,"d":"0.00"},"up","yes"]
[112153,0,"chr2","-",89085177,89085787,"ENST00000390252",2,442,"MSTRG.8934","IGKV3-15","GO:0016020(membrane);GO:0005886(plasma membrane);GO:0005576(extracellular region);GO:0006508(proteolysis);GO:0006955(immune response);GO:0002376(immune system process);GO:0003823(antigen binding);GO:0002250(adaptive immune response);GO:0004252(serine-type endopeptidase activity);GO:0006898(receptor-mediated endocytosis);GO:0006956(complement activation);GO:0006958(complement activation, classical pathway);GO:0030449(regulation of complement activation);GO:0038095(Fc-epsilon receptor signaling pathway);GO:0038096(Fc-gamma receptor signaling pathway involved in phagocytosis);GO:0050776(regulation of immune response);GO:0050900(leukocyte migration);GO:0070062(extracellular exosome);GO:0072562(blood microparticle)","NA","NA","NA","immunoglobulin kappa variable 3-15 [Source:HGNC Symbol;Acc:HGNC:5816]",{"v":21.51318,"d":"21.51"},{"v":1.500839,"d":"1.50"},{"v":14.3341024586914,"d":"14.33"},{"v":3.84137966678816,"d":"3.84"},{"v":2.42590459147447e-07,"d":"0.00"},{"v":1.98526487223616e-05,"d":"0.00"},"up","yes"]
[2869,0,"chr1","-",25244072,25247446,"ENST00000431849",3,1954,"MSTRG.260","RSRP1","GO:0005515(protein binding)","NA","NA","NA","arginine and serine rich protein 1 [Source:HGNC Symbol;Acc:HGNC:25234]",{"v":5.575719,"d":"5.58"},{"v":0.397707,"d":"0.40"},{"v":14.0196652309363,"d":"14.02"},{"v":3.8093799952035,"d":"3.81"},{"v":2.54671474919129e-07,"d":"0.00"},{"v":2.0756244943613e-05,"d":"0.00"},"up","yes"]
[137099,0,"chr3","-",52547990,52679713,"ENST00000296302",30,5145,"MSTRG.10994","PBRM1","GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0016569(covalent chromatin modification);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0003682(chromatin binding);GO:0008285(negative regulation of cell proliferation);GO:0006338(chromatin remodeling);GO:0000278(mitotic cell cycle);GO:0000228(nuclear chromosome);GO:0090544(BAF-type complex)","05225(Hepatocellular carcinoma)","K11757","NA","polybromo 1 [Source:HGNC Symbol;Acc:HGNC:30064]",{"v":2.050958,"d":"2.05"},{"v":0.14607,"d":"0.15"},{"v":14.0409255836243,"d":"14.04"},{"v":3.81156613671864,"d":"3.81"},{"v":2.5720382892498e-07,"d":"0.00"},{"v":2.08774229917642e-05,"d":"0.00"},"up","yes"]
[68190,0,"chr16","-",2088710,2135898,"ENST00000262304",46,14138,"MSTRG.5540","PKD1","GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0005737(cytoplasm);GO:0005634(nucleus);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0030246(carbohydrate binding);GO:0005886(plasma membrane);GO:0042995(cell projection);GO:0005515(protein binding);GO:0001822(kidney development);GO:0005929(cilium);GO:0070062(extracellular exosome);GO:0019901(protein kinase binding);GO:0007507(heart development);GO:0019904(protein domain specific binding);GO:0005887(integral component of plasma membrane);GO:0044325(ion channel binding);GO:0051216(cartilage development);GO:0000139(Golgi membrane);GO:0009653(anatomical structure morphogenesis);GO:0021510(spinal cord development);GO:0032092(positive regulation of protein binding);GO:0018105(peptidyl-serine phosphorylation);GO:0050982(detection of mechanical stimulus);GO:0048754(branching morphogenesis of an epithelial tube);GO:0007160(cell-matrix adhesion);GO:0007156(homophilic cell adhesion via plasma membrane adhesion molecules);GO:0005262(calcium channel activity);GO:0031514(motile cilium);GO:0021915(neural tube development);GO:0072177(mesonephric duct development);GO:0031659(positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle);GO:0016323(basolateral plasma membrane);GO:0007050(cell cycle arrest);GO:0006611(protein export from nucleus);GO:0007259(JAK-STAT cascade);GO:0043588(skin development);GO:0030660(Golgi-associated vesicle membrane);GO:0060170(ciliary membrane);GO:0061136(regulation of proteasomal protein catabolic process);GO:0001701(in utero embryonic development);GO:0048565(digestive tract development);GO:0072205(metanephric collecting duct development);GO:0070588(calcium ion transmembrane transport);GO:0072218(metanephric ascending thin limb development);GO:0060674(placenta blood vessel development);GO:0060428(lung epithelium development);GO:0001502(cartilage condensation);GO:0001568(blood vessel development);GO:0001889(liver development);GO:0001892(embryonic placenta development);GO:0006807(nitrogen compound metabolic process);GO:0006816(calcium ion transport);GO:0007161(calcium-independent cell-matrix adhesion);GO:0007204(positive regulation of cytosolic calcium ion concentration);GO:0016337(single organismal cell-cell adhesion);GO:0030010(establishment of cell polarity);GO:0030155(regulation of cell adhesion);GO:0034405(response to fluid shear stress);GO:0036303(lymph vessel morphogenesis);GO:0042994(cytoplasmic sequestering of transcription factor);GO:0048806(genitalia development);GO:0060236(regulation of mitotic spindle organization);GO:0072001(renal system development);GO:0072164(mesonephric tubule development);GO:0072237(metanephric proximal tubule development);GO:0072287(metanephric distal tubule morphogenesis);GO:0002133(polycystin complex);GO:0005794(Golgi apparatus);GO:0009986(cell surface);GO:0016328(lateral plasma membrane)","NA","NA","NA","polycystin 1, transient receptor potential channel interacting [Source:HGNC Symbol;Acc:HGNC:9008]",{"v":0.109209,"d":"0.11"},{"v":1.590983,"d":"1.59"},{"v":0.0686424682099055,"d":"0.07"},{"v":-3.86475476033223,"d":"-3.86"},{"v":2.71114906211665e-07,"d":"0.00"},{"v":2.18704220744919e-05,"d":"0.00"},"down","yes"]
[109519,0,"chr2","-",47818417,47905568,"ENST00000492225",16,2216,"MSTRG.8685","FBXO11","GO:0008270(zinc ion binding);GO:0016567(protein ubiquitination);GO:0000151(ubiquitin ligase complex);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0005730(nucleolus);GO:0005829(cytosol);GO:0005694(chromosome);GO:0005515(protein binding);GO:0006511(ubiquitin-dependent protein catabolic process);GO:0000209(protein polyubiquitination);GO:0043687(post-translational protein modification);GO:0004842(ubiquitin-protein transferase activity);GO:0005737(cytoplasm);GO:0035246(peptidyl-arginine N-methylation);GO:0006464(cellular protein modification process);GO:0016274(protein-arginine N-methyltransferase activity);GO:0007605(sensory perception of sound)","NA","NA","NA","F-box protein 11 [Source:HGNC Symbol;Acc:HGNC:13590]",{"v":6.67023,"d":"6.67"},{"v":0.484224,"d":"0.48"},{"v":13.7750916931007,"d":"13.78"},{"v":3.78399001693181,"d":"3.78"},{"v":2.71627838264923E-7,"d":"0.00"},{"v":2.18704220744919e-05,"d":"0.00"},"up","yes"]
[117257,0,"chr2","+",189661420,189670831,"ENST00000260952",6,2450,"MSTRG.9295","ASNSD1","GO:0004066(asparagine synthase (glutamine-hydrolyzing) activity);GO:0006529(asparagine biosynthetic process);GO:0003674(molecular_function);GO:0008150(biological_process);GO:0005575(cellular_component);GO:0008652(cellular amino acid biosynthetic process);GO:0006541(glutamine metabolic process);GO:0042803(protein homodimerization activity)","NA","NA","NA","asparagine synthetase domain containing 1 [Source:HGNC Symbol;Acc:HGNC:24910]",{"v":0.563114,"d":"0.56"},{"v":8.207896,"d":"8.21"},{"v":0.0686063761041807,"d":"0.07"},{"v":-3.86551352669423,"d":"-3.87"},{"v":2.79301268748415e-07,"d":"0.00"},{"v":2.23979427083066e-05,"d":"0.00"},"down","yes"]
[12713,0,"chr1","-",160995211,161021348,"ENST00000368026",10,4835,"MSTRG.1128","F11R","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0030054(cell junction);GO:0050900(leukocyte migration);GO:0046718(viral entry into host cell);GO:0005923(bicellular tight junction);GO:0045296(cadherin binding);GO:0070062(extracellular exosome);GO:0043547(positive regulation of GTPase activity);GO:0016032(viral process);GO:0006954(inflammatory response);GO:0030198(extracellular matrix organization);GO:0005911(cell-cell junction);GO:0030165(PDZ domain binding);GO:0090002(establishment of protein localization to plasma membrane);GO:2000249(regulation of actin cytoskeleton reorganization);GO:0001618(virus receptor activity);GO:0007179(transforming growth factor beta receptor signaling pathway);GO:0050892(intestinal absorption);GO:0034260(negative regulation of GTPase activity);GO:0031032(actomyosin structure organization);GO:0070830(bicellular tight junction assembly);GO:0090557(establishment of endothelial intestinal barrier);GO:0001817(regulation of cytokine production);GO:0007155(cell adhesion);GO:0009314(response to radiation);GO:0030154(cell differentiation);GO:0030855(epithelial cell differentiation);GO:0045777(positive regulation of blood pressure);GO:0090559(regulation of membrane permeability);GO:0031410(cytoplasmic vesicle);GO:0036057(slit diaphragm)","04514(Cell adhesion molecules (CAMs));04530(Tight junction);04670(Leukocyte transendothelial migration);05120(Epithelial cell signaling in Helicobacter pylori infection)","K06089","NA","F11 receptor [Source:HGNC Symbol;Acc:HGNC:14685]",{"v":0.391827,"d":"0.39"},{"v":5.651567,"d":"5.65"},{"v":0.0693306829769513,"d":"0.07"},{"v":-3.85036221718099,"d":"-3.85"},{"v":2.8266251225353e-07,"d":"0.00"},{"v":2.25768201787139e-05,"d":"0.00"},"down","yes"]
[105560,0,"chr19","+",54573792,54590287,"ENST00000251376",7,4429,"MSTRG.8423","LILRA2","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005576(extracellular region);GO:0002376(immune system process);GO:0002250(adaptive immune response);GO:0007165(signal transduction);GO:0004872(receptor activity);GO:0006952(defense response);GO:0003823(antigen binding)","04380(Osteoclast differentiation)","K06512","NA","leukocyte immunoglobulin like receptor A2 [Source:HGNC Symbol;Acc:HGNC:6603]",{"v":1.166046,"d":"1.17"},{"v":16.367332,"d":"16.37"},{"v":0.0712422769941979,"d":"0.07"},{"v":-3.81112256222149,"d":"-3.81"},{"v":2.85352480364584e-07,"d":"0.00"},{"v":2.27008698323506E-5,"d":"0.00"},"down","yes"]
[15474,0,"chr1","-",206905019,206921867,"ENST00000628511",7,1055,"MSTRG.1351","FCMR","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005576(extracellular region);GO:0002376(immune system process);GO:0043066(negative regulation of apoptotic process);GO:0006968(cellular defense response)","NA","NA","NA","Fc fragment of IgM receptor [Source:HGNC Symbol;Acc:HGNC:14315]",{"v":12.87916,"d":"12.88"},{"v":0.947168,"d":"0.95"},{"v":13.5975455251867,"d":"13.60"},{"v":3.76527435090578,"d":"3.77"},{"v":2.8702787394032e-07,"d":"0.00"},{"v":2.27369788778662e-05,"d":"0.00"},"up","yes"]
[86790,0,"chr17","+",63805508,63819209,"ENST00000584010",11,3929,"MSTRG.7135","DDX42","GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016607(nuclear speck);GO:0016020(membrane);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0005829(cytosol);GO:0016787(hydrolase activity);GO:0004386(helicase activity);GO:0005730(nucleolus);GO:0005515(protein binding);GO:0005654(nucleoplasm);GO:0004004(ATP-dependent RNA helicase activity);GO:0010501(RNA secondary structure unwinding);GO:0042981(regulation of apoptotic process);GO:0015030(Cajal body);GO:0000398(mRNA splicing, via spliceosome);GO:0008104(protein localization)","03040(Spliceosome)","NA","NA","DEAD-box helicase 42 [Source:HGNC Symbol;Acc:HGNC:18676]",{"v":7.191668,"d":"7.19"},{"v":0.546008,"d":"0.55"},{"v":13.1713601265915,"d":"13.17"},{"v":3.71933242655395,"d":"3.72"},{"v":2.88083716751811e-07,"d":"0.00"},{"v":2.27369788778662e-05,"d":"0.00"},"up","yes"]
[76345,0,"chr16","-",84565594,84618077,"ENST00000262428",4,1843,"MSTRG.6195","COTL1","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0003779(actin binding);GO:0005622(intracellular);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0008150(biological_process);GO:0070062(extracellular exosome);GO:0043312(neutrophil degranulation);GO:0019899(enzyme binding);GO:0034774(secretory granule lumen);GO:1904813(ficolin-1-rich granule lumen);GO:0050832(defense response to fungus)","NA","NA","NA","coactosin like F-actin binding protein 1 [Source:HGNC Symbol;Acc:HGNC:18304]",{"v":28.419109,"d":"28.42"},{"v":392.504822,"d":"392.50"},{"v":0.0724044837339603,"d":"0.07"},{"v":-3.78777714908979,"d":"-3.79"},{"v":2.937994142789e-07,"d":"0.00"},{"v":2.30967980485082e-05,"d":"0.00"},"down","yes"]
[24709,"j","chr11","+",308121,309410,"MSTRG.2061.5",2,1167,"MSTRG.2061","IFITM2","NA","NA","NA","NA","NA",{"v":0.895724,"d":"0.90"},{"v":13.178385,"d":"13.18"},{"v":0.0679691783173735,"d":"0.07"},{"v":-3.8789755076635,"d":"-3.88"},{"v":2.9811058262088e-07,"d":"0.00"},{"v":2.33438122108774e-05,"d":"0.00"},"down","yes"]
[145713,0,"chr4","+",6640091,6642729,"ENST00000320912",3,2049,"MSTRG.11514","MRFAP1","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005515(protein binding);GO:0048471(perinuclear region of cytoplasm)","NA","NA","NA","Morf4 family associated protein 1 [Source:HGNC Symbol;Acc:HGNC:24549]",{"v":8.896935,"d":"8.90"},{"v":0.664327,"d":"0.66"},{"v":13.3924031388157,"d":"13.39"},{"v":3.74334295662305,"d":"3.74"},{"v":3.00471937239097e-07,"d":"0.00"},{"v":2.33949169027776e-05,"d":"0.00"},"up","yes"]
[95767,0,"chr19","+",7680843,7687703,"ENST00000596148",2,5498,"MSTRG.7750","TRAPPC5","GO:0006810(transport);GO:0005794(Golgi apparatus);GO:0005783(endoplasmic reticulum);GO:0043547(positive regulation of GTPase activity);GO:0005515(protein binding);GO:0048193(Golgi vesicle transport);GO:0016192(vesicle-mediated transport);GO:0030008(TRAPP complex);GO:0000139(Golgi membrane);GO:0005829(cytosol);GO:0017112(Rab guanyl-nucleotide exchange factor activity);GO:0061024(membrane organization);GO:0048208(COPII vesicle coating)","NA","NA","NA","trafficking protein particle complex 5 [Source:HGNC Symbol;Acc:HGNC:23067]",{"v":0.251857,"d":"0.25"},{"v":3.624981,"d":"3.62"},{"v":0.0694781572648243,"d":"0.07"},{"v":-3.84729669911379,"d":"-3.85"},{"v":3.01106452524732e-07,"d":"0.00"},{"v":2.33949169027776e-05,"d":"0.00"},"down","yes"]
[13002,0,"chr1","-",161624223,161631158,"ENST00000421702",5,1055,"MSTRG.1160","FCGR3B","GO:0016020(membrane);GO:0005886(plasma membrane);GO:0005576(extracellular region);GO:0031225(anchored component of membrane);GO:0070062(extracellular exosome);GO:0006501(C-terminal protein lipidation);GO:0043312(neutrophil degranulation);GO:0006955(immune response);GO:0030667(secretory granule membrane);GO:0019864(IgG binding);GO:0016021(integral component of membrane)","04145(Phagosome);04650(Natural killer cell mediated cytotoxicity);04380(Osteoclast differentiation);05322(Systemic lupus erythematosus);05150(Staphylococcus aureus infection);05152(Tuberculosis);05140(Leishmaniasis)","K06463","NA","Fc fragment of IgG receptor IIIb [Source:HGNC Symbol;Acc:HGNC:3620]",{"v":5.485376,"d":"5.49"},{"v":76.450867,"d":"76.45"},{"v":0.071750343916963,"d":"0.07"},{"v":-3.80087044277932,"d":"-3.80"},{"v":3.02666083437537e-07,"d":"0.00"},{"v":2.34249471088401E-5,"d":"0.00"},"down","yes"]
[184082,0,"chr8","+",58553216,58582846,"ENST00000447182",9,2103,"MSTRG.14373","SDCBP","GO:0005737(cytoplasm);GO:0005634(nucleus);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0043231(intracellular membrane-bounded organelle);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0035556(intracellular signal transduction);GO:0031965(nuclear membrane);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005886(plasma membrane);GO:0030036(actin cytoskeleton organization);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0042470(melanosome);GO:0005615(extracellular space);GO:0030054(cell junction);GO:0045121(membrane raft);GO:0007268(chemical synaptic transmission);GO:0005925(focal adhesion);GO:0042802(identical protein binding);GO:0008289(lipid binding);GO:0045296(cadherin binding);GO:0006930(substrate-dependent cell migration, cell extension);GO:0070062(extracellular exosome);GO:0072562(blood microparticle);GO:0030335(positive regulation of cell migration);GO:0005912(adherens junction);GO:0005546(phosphatidylinositol-4,5-bisphosphate binding);GO:0043312(neutrophil degranulation);GO:0007346(regulation of mitotic cell cycle);GO:0008284(positive regulation of cell proliferation);GO:0032435(negative regulation of proteasomal ubiquitin-dependent protein catabolic process);GO:0006612(protein targeting to membrane);GO:0047485(protein N-terminus binding);GO:0030511(positive regulation of transforming growth factor beta receptor signaling pathway);GO:0046982(protein heterodimerization activity);GO:0048013(ephrin receptor signaling pathway);GO:0005109(frizzled binding);GO:0005137(interleukin-5 receptor binding);GO:0008093(cytoskeletal adaptor activity);GO:0045545(syndecan binding);GO:0002091(negative regulation of receptor internalization);GO:0010718(positive regulation of epithelial to mesenchymal transition);GO:0010862(positive regulation of pathway-restricted SMAD protein phosphorylation);GO:0030307(positive regulation of cell growth);GO:0042327(positive regulation of phosphorylation);GO:0046330(positive regulation of JNK cascade);GO:1903543(positive regulation of exosomal secretion);GO:1903553(positive regulation of extracellular exosome assembly);GO:0005895(interleukin-5 receptor complex);GO:0035578(azurophil granule lumen);GO:1903561(extracellular vesicle);GO:0008022(protein C-terminus binding);GO:0019838(growth factor binding);GO:0042043(neurexin family protein binding);GO:0042803(protein homodimerization activity);GO:0046875(ephrin receptor binding);GO:0050839(cell adhesion molecule binding);GO:0007265(Ras protein signal transduction);GO:0005622(intracellular)","NA","NA","NA","syndecan binding protein [Source:HGNC Symbol;Acc:HGNC:10662]",{"v":0.791747,"d":"0.79"},{"v":11.298862,"d":"11.30"},{"v":0.0700731631203213,"d":"0.07"},{"v":-3.83499416845398,"d":"-3.83"},{"v":3.11429573530309e-07,"d":"0.00"},{"v":2.40101379314796e-05,"d":"0.00"},"down","yes"]
[117414,"j","chr2","-",190970117,191014211,"MSTRG.9305.4",24,3034,"MSTRG.9305","STAT1","NA","NA","NA","NA","NA",{"v":1.327926,"d":"1.33"},{"v":18.457178,"d":"18.46"},{"v":0.0719463181207875,"d":"0.07"},{"v":-3.79693533136782,"d":"-3.80"},{"v":3.18536162237232E-7,"d":"0.00"},{"v":2.43981610557903e-05,"d":"0.00"},"down","yes"]
[69075,0,"chr16","-",4461680,4474895,"ENST00000283429",6,1376,"MSTRG.5604","NMRAL1","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0048471(perinuclear region of cytoplasm);GO:0005829(cytosol);GO:0000050(urea cycle)","NA","NA","NA","NmrA like redox sensor 1 [Source:HGNC Symbol;Acc:HGNC:24987]",{"v":8.050932,"d":"8.05"},{"v":0.589093,"d":"0.59"},{"v":13.6666570473592,"d":"13.67"},{"v":3.77258848845312,"d":"3.77"},{"v":3.18906251780913e-07,"d":"0.00"},{"v":2.43981610557903e-05,"d":"0.00"},"up","yes"]
[161894,0,"chr5","-",179614179,179623721,"ENST00000442819",14,2248,"MSTRG.12597","HNRNPH1","GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0006397(mRNA processing);GO:0008380(RNA splicing);GO:0005634(nucleus);GO:0016020(membrane);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0030529(intracellular ribonucleoprotein complex);GO:0005681(spliceosomal complex);GO:0005515(protein binding);GO:0043484(regulation of RNA splicing);GO:0000398(mRNA splicing, via spliceosome);GO:0008543(fibroblast growth factor receptor signaling pathway);GO:0016070(RNA metabolic process);GO:0006396(RNA processing);GO:0071013(catalytic step 2 spliceosome);GO:0008266(poly(U) RNA binding)","NA","NA","NA","heterogeneous nuclear ribonucleoprotein H1 [Source:HGNC Symbol;Acc:HGNC:5041]",{"v":27.243587,"d":"27.24"},{"v":2.127625,"d":"2.13"},{"v":12.804693966277,"d":"12.80"},{"v":3.6786008676501,"d":"3.68"},{"v":3.21622690199855E-7,"d":"0.00"},{"v":2.45120682363004e-05,"d":"0.00"},"up","yes"]
[182312,"j","chr8","+",25390866,25412910,"MSTRG.14244.10",11,2956,"MSTRG.14244","DOCK5","NA","NA","NA","NA","NA",{"v":6.31675,"d":"6.32"},{"v":0.481738,"d":"0.48"},{"v":13.1124179533273,"d":"13.11"},{"v":3.71286184052513,"d":"3.71"},{"v":3.26183916720198e-07,"d":"0.00"},{"v":2.47651728101479e-05,"d":"0.00"},"up","yes"]
[169882,"j","chr6","+",144539299,144852732,"MSTRG.13329.5",30,5624,"MSTRG.13329","UTRN","NA","NA","NA","NA","NA",{"v":8.397918,"d":"8.40"},{"v":0.656607,"d":"0.66"},{"v":12.7898697394332,"d":"12.79"},{"v":3.67692966581287,"d":"3.68"},{"v":3.30049173963079e-07,"d":"0.00"},{"v":2.49637193397529e-05,"d":"0.00"},"up","yes"]
[181289,0,"chr8","-",11842524,11868229,"ENST00000353047",10,3875,"MSTRG.14199","CTSB","GO:0008234(cysteine-type peptidase activity);GO:0006508(proteolysis);GO:0005615(extracellular space);GO:0043231(intracellular membrane-bounded organelle);GO:0005730(nucleolus);GO:0016787(hydrolase activity);GO:0005515(protein binding);GO:0008233(peptidase activity);GO:0005576(extracellular region);GO:0042470(melanosome);GO:0048471(perinuclear region of cytoplasm);GO:0004197(cysteine-type endopeptidase activity);GO:0046697(decidualization);GO:0046718(viral entry into host cell);GO:0050790(regulation of catalytic activity);GO:0005739(mitochondrion);GO:0005764(lysosome);GO:0004252(serine-type endopeptidase activity);GO:0070062(extracellular exosome);GO:0030574(collagen catabolic process);GO:0043312(neutrophil degranulation);GO:0042981(regulation of apoptotic process);GO:0005622(intracellular);GO:0002224(toll-like receptor signaling pathway);GO:1904813(ficolin-1-rich granule lumen);GO:0030855(epithelial cell differentiation);GO:0005518(collagen binding);GO:0043394(proteoglycan binding);GO:0051603(proteolysis involved in cellular protein catabolic process);GO:0097067(cellular response to thyroid hormone stimulus);GO:0036021(endolysosome lumen)","04142(Lysosome);04140(Autophagy - animal);04210(Apoptosis);04621(NOD-like receptor signaling pathway);04612(Antigen processing and presentation);04924(Renin secretion)","K01363","EC:3.4.22.1","cathepsin B [Source:HGNC Symbol;Acc:HGNC:2527]",{"v":6.077418,"d":"6.08"},{"v":82.191437,"d":"82.19"},{"v":0.0739422283126647,"d":"0.07"},{"v":-3.7574576687382,"d":"-3.76"},{"v":3.55933864711729e-07,"d":"0.00"},{"v":2.68199524926936E-5,"d":"0.00"},"down","yes"]
[96780,0,"chr19","+",11435288,11450965,"ENST00000591462",19,2209,"MSTRG.7840","PRKCSH","GO:0046872(metal ion binding);GO:0005783(endoplasmic reticulum);GO:0005509(calcium ion binding);GO:0044267(cellular protein metabolic process);GO:0005622(intracellular);GO:0043687(post-translational protein modification);GO:0044325(ion channel binding);GO:0006457(protein folding);GO:0006491(N-glycan processing);GO:0005788(endoplasmic reticulum lumen);GO:0035556(intracellular signal transduction);GO:0051219(phosphoprotein binding);GO:0005080(protein kinase C binding);GO:0003723(RNA binding);GO:0001701(in utero embryonic development);GO:0001889(liver development);GO:0006807(nitrogen compound metabolic process);GO:0010977(negative regulation of neuron projection development);GO:0051291(protein heterooligomerization);GO:0072001(renal system development)","04141(Protein processing in endoplasmic reticulum)","K08288","NA","protein kinase C substrate 80K-H [Source:HGNC Symbol;Acc:HGNC:9411]",{"v":0.943629,"d":"0.94"},{"v":13.175543,"d":"13.18"},{"v":0.0716197427309068,"d":"0.07"},{"v":-3.80349885348869,"d":"-3.80"},{"v":3.63567459871461e-07,"d":"0.00"},{"v":2.72212200257944E-5,"d":"0.00"},"down","yes"]
[133027,0,"chr3","+",9429950,9476478,"ENST00000302463",22,4786,"MSTRG.10639","SETD5","GO:0005634(nucleus);GO:0016569(covalent chromatin modification);GO:0016593(Cdc73/Paf1 complex);GO:1902275(regulation of chromatin organization);GO:0035065(regulation of histone acetylation)","NA","NA","NA","SET domain containing 5 [Source:HGNC Symbol;Acc:HGNC:25566]",{"v":2.826129,"d":"2.83"},{"v":0.213985,"d":"0.21"},{"v":13.2071360142066,"d":"13.21"},{"v":3.72324574496427,"d":"3.72"},{"v":3.63985664407407e-07,"d":"0.00"},{"v":2.72212200257944E-5,"d":"0.00"},"up","yes"]
[11800,0,"chr1","-",155659443,155688656,"ENST00000368339",10,3073,"MSTRG.1062","YY1AP1","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0001650(fibrillar center);GO:0005515(protein binding);GO:0030154(cell differentiation);GO:0005654(nucleoplasm);GO:0005730(nucleolus);GO:0008283(cell proliferation);GO:0051726(regulation of cell cycle);GO:0031011(Ino80 complex)","NA","NA","NA","YY1 associated protein 1 [Source:HGNC Symbol;Acc:HGNC:30935]",{"v":0.228152,"d":"0.23"},{"v":3.371269,"d":"3.37"},{"v":0.0676754065012314,"d":"0.07"},{"v":-3.88522454157092,"d":"-3.89"},{"v":3.7211939749774e-07,"d":"0.00"},{"v":2.77256721240107E-5,"d":"0.00"},"down","yes"]
[171421,0,"chr7","-",2728112,2844324,"ENST00000275364",4,4378,"MSTRG.13459","GNA12","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005525(GTP binding);GO:0007264(small GTPase mediated signal transduction);GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0007186(G-protein coupled receptor signaling pathway);GO:0007165(signal transduction);GO:0003924(GTPase activity);GO:0004871(signal transducer activity);GO:0005886(plasma membrane);GO:0001664(G-protein coupled receptor binding);GO:0019001(guanyl nucleotide binding);GO:0031683(G-protein beta/gamma-subunit complex binding);GO:0005925(focal adhesion);GO:0005515(protein binding);GO:0007266(Rho protein signal transduction);GO:0007188(adenylate cyclase-modulating G-protein coupled receptor signaling pathway);GO:0005834(heterotrimeric G-protein complex);GO:0016328(lateral plasma membrane);GO:0007596(blood coagulation);GO:0030168(platelet activation);GO:0032006(regulation of TOR signaling);GO:0032434(regulation of proteasomal ubiquitin-dependent protein catabolic process);GO:0031526(brush border membrane);GO:0031752(D5 dopamine receptor binding);GO:0001701(in utero embryonic development);GO:0008360(regulation of cell shape);GO:0010762(regulation of fibroblast migration);GO:0030154(cell differentiation);GO:0035556(intracellular signal transduction);GO:0042493(response to drug);GO:0042733(embryonic digit morphogenesis)","04010(MAPK signaling pathway);04072(Phospholipase D signaling pathway);04071(Sphingolipid signaling pathway);04022(cGMP - PKG signaling pathway);04810(Regulation of actin cytoskeleton);04270(Vascular smooth muscle contraction);04730(Long-term depression);05200(Pathways in cancer)","K04346","NA","G protein subunit alpha 12 [Source:HGNC Symbol;Acc:HGNC:4380]",{"v":0.541733,"d":"0.54"},{"v":7.495042,"d":"7.50"},{"v":0.0722788478036547,"d":"0.07"},{"v":-3.79028268137523,"d":"-3.79"},{"v":3.76402455916502E-7,"d":"0.00"},{"v":2.79405362072145e-05,"d":"0.00"},"down","yes"]
[196642,0,"chrX","+",44873177,45112598,"ENST00000382899",29,5789,"MSTRG.15250","KDM6A","GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0016569(covalent chromatin modification);GO:0051213(dioxygenase activity);GO:0071558(histone demethylase activity (H3-K27 specific));GO:0010468(regulation of gene expression);GO:0071557(histone H3-K27 demethylation);GO:0005654(nucleoplasm);GO:0035097(histone methyltransferase complex);GO:0032452(histone demethylase activity);GO:0051568(histone H3-K4 methylation);GO:0044666(MLL3/4 complex);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:0031490(chromatin DNA binding);GO:0042802(identical protein binding);GO:0001701(in utero embryonic development);GO:0001843(neural tube closure);GO:0003007(heart morphogenesis);GO:0003016(respiratory system process);GO:0007507(heart development);GO:0010628(positive regulation of gene expression);GO:0021915(neural tube development);GO:0032525(somite rostral/caudal axis specification);GO:0035264(multicellular organism growth);GO:0048333(mesodermal cell differentiation);GO:0048568(embryonic organ development);GO:0048570(notochord morphogenesis);GO:0060070(canonical Wnt signaling pathway);GO:0072358(cardiovascular system development)","05202(Transcriptional misregulation in cancers)","K11447","EC:1.14.11.-","lysine demethylase 6A [Source:HGNC Symbol;Acc:HGNC:12637]",{"v":0.357841,"d":"0.36"},{"v":4.971235,"d":"4.97"},{"v":0.0719823142539027,"d":"0.07"},{"v":-3.79621370366995,"d":"-3.80"},{"v":3.81634858019549e-07,"d":"0.00"},{"v":2.81296564642495e-05,"d":"0.00"},"down","yes"]
[183959,0,"chr8","-",56073042,56074506,"ENST00000524349",3,752,"MSTRG.14365","RPS20","GO:0003723(RNA binding);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0006412(translation);GO:0030529(intracellular ribonucleoprotein complex);GO:0005622(intracellular);GO:0003735(structural constituent of ribosome);GO:0005840(ribosome);GO:0015935(small ribosomal subunit);GO:0005515(protein binding);GO:0022627(cytosolic small ribosomal subunit);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0031012(extracellular matrix);GO:0002181(cytoplasmic translation);GO:0006413(translational initiation);GO:0006364(rRNA processing);GO:0000184(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay);GO:0019083(viral transcription);GO:0006614(SRP-dependent cotranslational protein targeting to membrane)","03010(Ribosome)","NA","NA","ribosomal protein S20 [Source:HGNC Symbol;Acc:HGNC:10405]",{"v":20.735884,"d":"20.74"},{"v":1.586898,"d":"1.59"},{"v":13.0669293174483,"d":"13.07"},{"v":3.70784824757596,"d":"3.71"},{"v":3.81767673367969e-07,"d":"0.00"},{"v":2.81296564642495e-05,"d":"0.00"},"up","yes"]
[179058,0,"chr7","-",135926761,135977316,"ENST00000393085",4,3738,"MSTRG.13993","MTPN","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0048471(perinuclear region of cytoplasm);GO:0070062(extracellular exosome);GO:0006417(regulation of translation);GO:0051092(positive regulation of NF-kappaB transcription factor activity);GO:0030307(positive regulation of cell growth);GO:0030182(neuron differentiation);GO:0016049(cell growth);GO:0010613(positive regulation of cardiac muscle hypertrophy);GO:0016202(regulation of striated muscle tissue development);GO:0043565(sequence-specific DNA binding);GO:0006584(catecholamine metabolic process);GO:0010557(positive regulation of macromolecule biosynthetic process);GO:0021707(cerebellar granule cell differentiation);GO:0043403(skeletal muscle tissue regeneration);GO:0051146(striated muscle cell differentiation);GO:0051247(positive regulation of protein metabolic process);GO:0071260(cellular response to mechanical stimulus);GO:2000812(regulation of barbed-end actin filament capping);GO:0008290(F-actin capping protein complex);GO:0030424(axon)","NA","NA","NA","myotrophin [Source:HGNC Symbol;Acc:HGNC:15667]",{"v":15.090589,"d":"15.09"},{"v":1.207451,"d":"1.21"},{"v":12.4978893553444,"d":"12.50"},{"v":3.64361256787996,"d":"3.64"},{"v":3.89031055931298e-07,"d":"0.00"},{"v":2.85594563413094e-05,"d":"0.00"},"up","yes"]
[121832,0,"chr20","-",5544404,5611026,"ENST00000379019",20,5489,"MSTRG.9589","GPCPD1","GO:0005737(cytoplasm);GO:0030246(carbohydrate binding);GO:0016787(hydrolase activity);GO:0006629(lipid metabolic process);GO:0005829(cytosol);GO:0008081(phosphoric diester hydrolase activity);GO:0047389(glycerophosphocholine phosphodiesterase activity);GO:0046475(glycerophospholipid catabolic process);GO:2001070(starch binding);GO:0030643(cellular phosphate ion homeostasis);GO:0008889(glycerophosphodiester phosphodiesterase activity);GO:0007519(skeletal muscle tissue development)","00564(Glycerophospholipid metabolism);05231(Choline metabolism in cancer)","K18695","EC:3.1.4.2","glycerophosphocholine phosphodiesterase 1 [Source:HGNC Symbol;Acc:HGNC:26957]",{"v":0.113467,"d":"0.11"},{"v":1.671491,"d":"1.67"},{"v":0.0678837038308911,"d":"0.07"},{"v":-3.88079090726478,"d":"-3.88"},{"v":3.96769361226037e-07,"d":"0.00"},{"v":2.89363010896804e-05,"d":"0.00"},"down","yes"]
[133103,0,"chr3","-",9783128,9792736,"ENST00000343450",8,2554,"MSTRG.10648","TADA3","GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0005515(protein binding);GO:0004402(histone acetyltransferase activity);GO:0003713(transcription coactivator activity);GO:0045893(positive regulation of transcription, DNA-templated);GO:0010628(positive regulation of gene expression);GO:0016579(protein deubiquitination);GO:0019904(protein domain specific binding);GO:0033276(transcription factor TFTC complex);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0030520(intracellular estrogen receptor signaling pathway);GO:0005622(intracellular);GO:0036459(thiol-dependent ubiquitinyl hydrolase activity);GO:0043966(histone H3 acetylation);GO:0005671(Ada2/Gcn5/Ada3 transcription activator complex);GO:0000124(SAGA complex);GO:0030914(STAGA complex);GO:0016922(ligand-dependent nuclear receptor binding);GO:0030374(ligand-dependent nuclear receptor transcription coactivator activity);GO:0000278(mitotic cell cycle);GO:0001932(regulation of protein phosphorylation);GO:0031063(regulation of histone deacetylation);GO:0031647(regulation of protein stability);GO:0043967(histone H4 acetylation);GO:0090043(regulation of tubulin deacetylation);GO:0072686(mitotic spindle)","05165(Human papillomavirus infection)","K11315","NA","transcriptional adaptor 3 [Source:HGNC Symbol;Acc:HGNC:19422]",{"v":7.388505,"d":"7.39"},{"v":0.571777,"d":"0.57"},{"v":12.9220045577209,"d":"12.92"},{"v":3.69175798389443,"d":"3.69"},{"v":3.97062625128827e-07,"d":"0.00"},{"v":2.89363010896804e-05,"d":"0.00"},"up","yes"]
[11442,0,"chr1","-",154582067,154627964,"ENST00000368471",15,6515,"MSTRG.1019","ADAR","GO:0003723(RNA binding);GO:0006396(RNA processing);GO:0006397(mRNA processing);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0046872(metal ion binding);GO:0005730(nucleolus);GO:0005654(nucleoplasm);GO:0016787(hydrolase activity);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0002376(immune system process);GO:0045087(innate immune response);GO:0031047(gene silencing by RNA);GO:0051607(defense response to virus);GO:0004000(adenosine deaminase activity);GO:0009615(response to virus);GO:0003726(double-stranded RNA adenosine deaminase activity);GO:0060337(type I interferon signaling pathway);GO:0045070(positive regulation of viral genome replication);GO:0044387(negative regulation of protein kinase activity by regulation of protein phosphorylation);GO:0035455(response to interferon-alpha);GO:0044530(supraspliceosomal complex);GO:0001649(osteoblast differentiation);GO:0001701(in utero embryonic development);GO:0002244(hematopoietic progenitor cell differentiation);GO:0002566(somatic diversification of immune receptors via somatic mutation);GO:0006382(adenosine to inosine editing);GO:0016553(base conversion or substitution editing);GO:0030218(erythrocyte differentiation);GO:0031054(pre-miRNA processing);GO:0035196(production of miRNAs involved in gene silencing by miRNA);GO:0035280(miRNA loading onto RISC involved in gene silencing by miRNA);GO:0043066(negative regulation of apoptotic process);GO:0045071(negative regulation of viral genome replication);GO:0060216(definitive hemopoiesis);GO:0060339(negative regulation of type I interferon-mediated signaling pathway);GO:0061484(hematopoietic stem cell homeostasis);GO:0098586(cellular response to virus);GO:1900369(negative regulation of RNA interference)","04623(Cytosolic DNA-sensing pathway);05162(Measles);05164(Influenza A)","K12968","EC:3.5.4.37","adenosine deaminase, RNA specific [Source:HGNC Symbol;Acc:HGNC:225]",{"v":10.45087,"d":"10.45"},{"v":0.839507,"d":"0.84"},{"v":12.4488181754292,"d":"12.45"},{"v":3.63793688188936,"d":"3.64"},{"v":3.99543560218629e-07,"d":"0.00"},{"v":2.9011221128893e-05,"d":"0.00"},"up","yes"]
[196029,0,"chrX","-",19533975,19887601,"ENST00000397821",18,4731,"MSTRG.15198","SH3KBP1","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0006915(apoptotic process);GO:0030054(cell junction);GO:0045202(synapse);GO:0030659(cytoplasmic vesicle membrane);GO:0031410(cytoplasmic vesicle);GO:0005925(focal adhesion);GO:0005886(plasma membrane);GO:0005829(cytosol);GO:0006897(endocytosis);GO:0061024(membrane organization);GO:0007010(cytoskeleton organization);GO:0017124(SH3 domain binding);GO:0008360(regulation of cell shape);GO:0043005(neuron projection);GO:0007411(axon guidance);GO:0016477(cell migration);GO:0007267(cell-cell signaling);GO:0042059(negative regulation of epidermal growth factor receptor signaling pathway);GO:0030139(endocytic vesicle);GO:0005911(cell-cell junction)","04144(Endocytosis)","K12470","NA","SH3 domain containing kinase binding protein 1 [Source:HGNC Symbol;Acc:HGNC:13867]",{"v":2.302458,"d":"2.30"},{"v":30.752857,"d":"30.75"},{"v":0.0748697267379093,"d":"0.07"},{"v":-3.73947370091472,"d":"-3.74"},{"v":4.03541251863361E-7,"d":"0.00"},{"v":2.91933123326925e-05,"d":"0.00"},"down","yes"]
[175991,0,"chr7","+",92070138,92109061,"ENST00000394534",23,5652,"ENSG00000127914","AKAP9","GO:0060307(regulation of ventricular cardiac muscle cell membrane repolarization);GO:0005737(cytoplasm);GO:0005794(Golgi apparatus);GO:0043231(intracellular membrane-bounded organelle);GO:0003677(DNA binding);GO:0007165(signal transduction);GO:0005813(centrosome);GO:0032947(protein complex scaffold);GO:0043547(positive regulation of GTPase activity);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0005815(microtubule organizing center);GO:0005829(cytosol);GO:0000165(MAPK cascade);GO:0006810(transport);GO:0000086(G2/M transition of mitotic cell cycle);GO:0010389(regulation of G2/M transition of mitotic cell cycle);GO:0097711(ciliary basal body docking);GO:0033138(positive regulation of peptidyl-serine phosphorylation);GO:0044325(ion channel binding);GO:0061337(cardiac conduction);GO:0005795(Golgi stack);GO:0005102(receptor binding);GO:0007268(chemical synaptic transmission);GO:0005088(Ras guanyl-nucleotide exchange factor activity);GO:0060306(regulation of membrane repolarization);GO:0008076(voltage-gated potassium channel complex);GO:0034237(protein kinase A regulatory subunit binding);GO:0086091(regulation of heart rate by cardiac conduction);GO:0071320(cellular response to cAMP);GO:0015459(potassium channel regulator activity);GO:0007020(microtubule nucleation);GO:1901018(positive regulation of potassium ion transmembrane transporter activity);GO:0098909(regulation of cardiac muscle cell action potential involved in regulation of contraction);GO:0051661(maintenance of centrosome location);GO:0005801(cis-Golgi network);GO:0007194(negative regulation of adenylate cyclase activity);GO:0051602(response to electrical stimulus);GO:0043025(neuronal cell body);GO:0044307(dendritic branch);GO:0097060(synaptic membrane);GO:0016301(kinase activity);GO:0016310(phosphorylation)","NA","NA","NA","A-kinase anchoring protein 9 [Source:HGNC Symbol;Acc:HGNC:379]",{"v":1.854664,"d":"1.85"},{"v":0.140312,"d":"0.14"},{"v":13.2181424254519,"d":"13.22"},{"v":3.72444754087919,"d":"3.72"},{"v":4.04975336345944e-07,"d":"0.00"},{"v":2.91933123326925e-05,"d":"0.00"},"up","yes"]
[22692,0,"chr10","+",97713724,97718152,"ENST00000285605",2,3221,"ENSG00000155254","MARVELD1","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005886(plasma membrane);GO:0005856(cytoskeleton);GO:0007049(cell cycle);GO:0008104(protein localization);GO:0019911(structural constituent of myelin sheath);GO:0042552(myelination);GO:0045121(membrane raft);GO:0001766(membrane raft polarization)","NA","NA","NA","MARVEL domain containing 1 [Source:HGNC Symbol;Acc:HGNC:28674]",{"v":0.300401,"d":"0.30"},{"v":4.291749,"d":"4.29"},{"v":0.0699950066977356,"d":"0.07"},{"v":-3.83660418299371,"d":"-3.84"},{"v":4.24259322374973e-07,"d":"0.00"},{"v":3.04734178028182e-05,"d":"0.00"},"down","yes"]
[175191,"j","chr7","-",75417503,75485976,"MSTRG.13731.4",16,4886,"MSTRG.13731","POM121C","NA","NA","NA","NA","NA",{"v":0.997541,"d":"1.00"},{"v":13.360598,"d":"13.36"},{"v":0.074662900567774,"d":"0.07"},{"v":-3.74346463300277,"d":"-3.74"},{"v":4.3575651267912e-07,"d":"0.00"},{"v":3.10884045031636e-05,"d":"0.00"},"down","yes"]
[63700,0,"chr15","-",65578782,65611245,"ENST00000313182",12,2393,"MSTRG.5199","INTS14","GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0042795(snRNA transcription from RNA polymerase II promoter);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005737(cytoplasm)","NA","NA","NA","integrator complex subunit 14 [Source:HGNC Symbol;Acc:HGNC:25372]",{"v":3.835303,"d":"3.84"},{"v":0.287904,"d":"0.29"},{"v":13.3214647938202,"d":"13.32"},{"v":3.73568082103469,"d":"3.74"},{"v":4.35935159299168E-7,"d":"0.00"},{"v":3.10884045031636e-05,"d":"0.00"},"up","yes"]
[63732,0,"chr15","-",65661815,65761437,"ENST00000635620",33,5887,"MSTRG.5202","DENND4A","GO:0005634(nucleus);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0043547(positive regulation of GTPase activity);GO:0005085(guanyl-nucleotide exchange factor activity);GO:0005829(cytosol);GO:0017112(Rab guanyl-nucleotide exchange factor activity);GO:0061024(membrane organization)","NA","NA","NA","DENN domain containing 4A [Source:HGNC Symbol;Acc:HGNC:24321]",{"v":1.5046,"d":"1.50"},{"v":0.113361,"d":"0.11"},{"v":13.2726422667408,"d":"13.27"},{"v":3.73038370038528,"d":"3.73"},{"v":4.4415558670226e-07,"d":"0.00"},{"v":3.15539214952008e-05,"d":"0.00"},"up","yes"]
[3503,0,"chr1","-",29147853,29173494,"ENST00000634348",7,8128,"MSTRG.333","SRSF4","GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0006397(mRNA processing);GO:0008380(RNA splicing);GO:0005634(nucleus);GO:0016607(nuclear speck);GO:0005515(protein binding);GO:0005654(nucleoplasm);GO:0006369(termination of RNA polymerase II transcription);GO:0006405(RNA export from nucleus);GO:0031124(mRNA 3'-end processing);GO:0048025(negative regulation of mRNA splicing, via spliceosome);GO:0000398(mRNA splicing, via spliceosome);GO:0006406(mRNA export from nucleus);GO:1990825(sequence-specific mRNA binding);GO:0000375(RNA splicing, via transesterification reactions);GO:0032868(response to insulin)","03040(Spliceosome);05168(Herpes simplex infection)","NA","NA","serine and arginine rich splicing factor 4 [Source:HGNC Symbol;Acc:HGNC:10786]",{"v":1.18167,"d":"1.18"},{"v":0.089189,"d":"0.09"},{"v":13.2490553767841,"d":"13.25"},{"v":3.72781759782282,"d":"3.73"},{"v":4.45623290346886E-7,"d":"0.00"},{"v":3.15539214952008e-05,"d":"0.00"},"up","yes"]
[47464,"j","chr12","+",120534365,120577594,"MSTRG.3797.4",18,3912,"MSTRG.3797","RNF10","NA","NA","NA","NA","NA",{"v":8.738239,"d":"8.74"},{"v":0.703227,"d":"0.70"},{"v":12.4259151028046,"d":"12.43"},{"v":3.63528019743256,"d":"3.64"},{"v":4.49555212053391e-07,"d":"0.00"},{"v":3.17198532660145e-05,"d":"0.00"},"up","yes"]
[113848,0,"chr2","+",117814650,117832379,"ENST00000263239",14,3796,"MSTRG.9069","DDX18","GO:0003676(nucleic acid binding);GO:0005524(ATP binding);GO:0003723(RNA binding);GO:0005634(nucleus);GO:0016020(membrane);GO:0000166(nucleotide binding);GO:0005730(nucleolus);GO:0016787(hydrolase activity);GO:0004386(helicase activity);GO:0005694(chromosome);GO:0071392(cellular response to estradiol stimulus);GO:0005737(cytoplasm);GO:0005515(protein binding);GO:0010501(RNA secondary structure unwinding);GO:0004004(ATP-dependent RNA helicase activity)","NA","NA","NA","DEAD-box helicase 18 [Source:HGNC Symbol;Acc:HGNC:2741]",{"v":0.273236,"d":"0.27"},{"v":3.818889,"d":"3.82"},{"v":0.0715485577087996,"d":"0.07"},{"v":-3.8049335046863,"d":"-3.80"},{"v":4.55211889338095e-07,"d":"0.00"},{"v":3.20058838250108E-5,"d":"0.00"},"down","yes"]
[138608,0,"chr3","+",100261012,100325238,"ENST00000394144",19,3677,"MSTRG.11086","TBC1D23","GO:0005794(Golgi apparatus);GO:0005515(protein binding);GO:0032680(regulation of tumor necrosis factor production);GO:0032755(positive regulation of interleukin-6 production);GO:0050727(regulation of inflammatory response)","NA","NA","NA","TBC1 domain family member 23 [Source:HGNC Symbol;Acc:HGNC:25622]",{"v":0.189645,"d":"0.19"},{"v":2.747249,"d":"2.75"},{"v":0.0690308741581123,"d":"0.07"},{"v":-3.85661443610741,"d":"-3.86"},{"v":4.63072011385772e-07,"d":"0.00"},{"v":3.24442874503547e-05,"d":"0.00"},"down","yes"]
[16533,0,"chr1","+",226062678,226071999,"ENST00000366815",4,1088,"MSTRG.1426","H3F3A","GO:0005634(nucleus);GO:0003677(DNA binding);GO:0046982(protein heterodimerization activity);GO:0006334(nucleosome assembly);GO:0000786(nucleosome);GO:0005694(chromosome);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0005654(nucleoplasm);GO:0070062(extracellular exosome);GO:0044267(cellular protein metabolic process);GO:1902036(regulation of hematopoietic stem cell differentiation);GO:0043234(protein complex);GO:0000784(nuclear chromosome, telomeric region);GO:0045815(positive regulation of gene expression, epigenetic);GO:0042393(histone binding);GO:0030307(positive regulation of cell growth);GO:0045652(regulation of megakaryocyte differentiation);GO:0006336(DNA replication-independent nucleosome assembly);GO:0007596(blood coagulation);GO:0000228(nuclear chromosome);GO:0060964(regulation of gene silencing by miRNA);GO:0000183(chromatin silencing at rDNA);GO:0045814(negative regulation of gene expression, epigenetic);GO:0000979(RNA polymerase II core promoter sequence-specific DNA binding);GO:0031492(nucleosomal DNA binding);GO:0000980(RNA polymerase II distal enhancer sequence-specific DNA binding);GO:0000788(nuclear nucleosome);GO:0032200(telomere organization);GO:0001649(osteoblast differentiation);GO:0006997(nucleus organization);GO:0007283(spermatogenesis);GO:0007286(spermatid development);GO:0007338(single fertilization);GO:0007420(brain development);GO:0007566(embryo implantation);GO:0008283(cell proliferation);GO:0008584(male gonad development);GO:0009725(response to hormone);GO:0031508(pericentric heterochromatin assembly);GO:0031509(telomeric heterochromatin assembly);GO:0035264(multicellular organism growth);GO:0042692(muscle cell differentiation);GO:0048477(oogenesis);GO:0090230(regulation of centromere complex assembly);GO:1902340(negative regulation of chromosome condensation);GO:0001740(Barr body)","05202(Transcriptional misregulation in cancers);05322(Systemic lupus erythematosus);05034(Alcoholism)","K11253","NA","H3 histone family member 3A [Source:HGNC Symbol;Acc:HGNC:4764]",{"v":9.232619,"d":"9.23"},{"v":121.430626,"d":"121.43"},{"v":0.07603204647895,"d":"0.08"},{"v":-3.71724856659303,"d":"-3.72"},{"v":4.73311935343549e-07,"d":"0.00"},{"v":3.30457787585314e-05,"d":"0.00"},"down","yes"]
[63584,0,"chr15","+",64841883,64868000,"ENST00000616065",5,3569,"MSTRG.5189","PLEKHO2","GO:0005576(extracellular region);GO:0043312(neutrophil degranulation);GO:1904813(ficolin-1-rich granule lumen)","04060(Cytokine-cytokine receptor interaction)","NA","NA","pleckstrin homology domain containing O2 [Source:HGNC Symbol;Acc:HGNC:30026]",{"v":4.635998,"d":"4.64"},{"v":0.366987,"d":"0.37"},{"v":12.6325946150681,"d":"12.63"},{"v":3.65907908031945,"d":"3.66"},{"v":4.75630695334786e-07,"d":"0.00"},{"v":3.30919641966725e-05,"d":"0.00"},"up","yes"]
[153041,0,"chr5","+",446149,467285,"ENST00000315013",12,2682,"MSTRG.11953","EXOC3","GO:0006810(transport);GO:0005737(cytoplasm);GO:0015031(protein transport);GO:0006887(exocytosis);GO:0000145(exocyst);GO:0005794(Golgi apparatus);GO:0042995(cell projection);GO:0048471(perinuclear region of cytoplasm);GO:0030496(midbody);GO:0005515(protein binding);GO:0005829(cytosol);GO:0045296(cadherin binding);GO:0030426(growth cone);GO:0000149(SNARE binding);GO:0030667(secretory granule membrane);GO:0051601(exocyst localization)","NA","NA","NA","exocyst complex component 3 [Source:HGNC Symbol;Acc:HGNC:30378]",{"v":6.605461,"d":"6.61"},{"v":0.525673,"d":"0.53"},{"v":12.5657224167876,"d":"12.57"},{"v":3.65142171056729,"d":"3.65"},{"v":4.795328148296E-7,"d":"0.00"},{"v":3.32476084948523e-05,"d":"0.00"},"up","yes"]
[15152,0,"chr1","+",204516383,204558120,"ENST00000367182",11,10073,"ENSG00000198625","MDM4","GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0043066(negative regulation of apoptotic process);GO:0016567(protein ubiquitination);GO:0008270(zinc ion binding);GO:0005515(protein binding);GO:0071157(negative regulation of cell cycle arrest);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0061630(ubiquitin protein ligase activity);GO:0006977(DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest);GO:0005654(nucleoplasm);GO:0050821(protein stabilization);GO:0016579(protein deubiquitination);GO:0008283(cell proliferation);GO:0019899(enzyme binding);GO:1901796(regulation of signal transduction by p53 class mediator);GO:0008285(negative regulation of cell proliferation);GO:0042177(negative regulation of protein catabolic process);GO:0006461(protein complex assembly);GO:0030330(DNA damage response, signal transduction by p53 class mediator);GO:0045023(G0 to G1 transition);GO:0071456(cellular response to hypoxia)","04115(p53 signaling pathway);05206(MicroRNAs in cancer)","K10127","NA","MDM4, p53 regulator [Source:HGNC Symbol;Acc:HGNC:6974]",{"v":0.094845,"d":"0.09"},{"v":1.32131,"d":"1.32"},{"v":0.0717810354875086,"d":"0.07"},{"v":-3.80025345466868,"d":"-3.80"},{"v":4.83949264214445e-07,"d":"0.00"},{"v":3.34377124838548e-05,"d":"0.00"},"down","yes"]
[123113,"j","chr20","-",34742338,34782314,"MSTRG.9679.16",9,3844,"MSTRG.9679","NCOA6","NA","NA","NA","NA","NA",{"v":8.279537,"d":"8.28"},{"v":0.674186,"d":"0.67"},{"v":12.2807904643526,"d":"12.28"},{"v":3.61833151897487,"d":"3.62"},{"v":5.02605819090002e-07,"d":"0.00"},{"v":3.46070103296178e-05,"d":"0.00"},"up","yes"]
[3993,0,"chr1","-",32936454,32964685,"ENST00000356990",9,2598,"MSTRG.379","RNF19B","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0046872(metal ion binding);GO:0005829(cytosol);GO:0016740(transferase activity);GO:0016567(protein ubiquitination);GO:0004842(ubiquitin-protein transferase activity);GO:0005515(protein binding);GO:0002376(immune system process);GO:0002250(adaptive immune response);GO:0000151(ubiquitin ligase complex);GO:0061630(ubiquitin protein ligase activity);GO:0000209(protein polyubiquitination);GO:0042787(protein ubiquitination involved in ubiquitin-dependent protein catabolic process);GO:0032436(positive regulation of proteasomal ubiquitin-dependent protein catabolic process);GO:0031624(ubiquitin conjugating enzyme binding);GO:0044194(cytolytic granule)","NA","NA","NA","ring finger protein 19B [Source:HGNC Symbol;Acc:HGNC:26886]",{"v":0.863099,"d":"0.86"},{"v":11.511669,"d":"11.51"},{"v":0.0749760091260442,"d":"0.07"},{"v":-3.73742715485687,"d":"-3.74"},{"v":5.20110133581463e-07,"d":"0.00"},{"v":3.56892066919404e-05,"d":"0.00"},"down","yes"]
[192671,"j","chr9","-",112218604,112333620,"MSTRG.14903.5",13,6845,"MSTRG.14903","PTBP3","NA","NA","NA","NA","NA",{"v":4.699723,"d":"4.70"},{"v":0.386519,"d":"0.39"},{"v":12.159099552674,"d":"12.16"},{"v":3.60396448822542,"d":"3.60"},{"v":5.37038381431983e-07,"d":"0.00"},{"v":3.67245972617597e-05,"d":"0.00"},"up","yes"]
[137460,0,"chr3","+",57556277,57566844,"ENST00000311180",3,8773,"ENSG00000174840","PDE12","GO:0006397(mRNA processing);GO:0046872(metal ion binding);GO:0016787(hydrolase activity);GO:0005739(mitochondrion);GO:0090305(nucleic acid phosphodiester bond hydrolysis);GO:0004527(exonuclease activity);GO:0004518(nuclease activity);GO:0005759(mitochondrial matrix);GO:0004535(poly(A)-specific ribonuclease activity);GO:0090503(RNA phosphodiester bond hydrolysis, exonucleolytic)","NA","NA","NA","phosphodiesterase 12 [Source:HGNC Symbol;Acc:HGNC:25386]",{"v":0.08564,"d":"0.09"},{"v":1.200604,"d":"1.20"},{"v":0.0713307635156971,"d":"0.07"},{"v":-3.80933177370092,"d":"-3.81"},{"v":5.40104273017971e-07,"d":"0.00"},{"v":3.67797237273654e-05,"d":"0.00"},"down","yes"]
[95141,0,"chr19","-",4675764,4714220,"ENST00000597145",19,4257,"ENSG00000142002","DPP9","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0016787(hydrolase activity);GO:0008233(peptidase activity);GO:0006508(proteolysis);GO:0008236(serine-type peptidase activity);GO:0004177(aminopeptidase activity);GO:0042802(identical protein binding)","NA","NA","NA","dipeptidyl peptidase 9 [Source:HGNC Symbol;Acc:HGNC:18648]",{"v":3.620323,"d":"3.62"},{"v":0.290648,"d":"0.29"},{"v":12.4560396080482,"d":"12.46"},{"v":3.63877353194456,"d":"3.64"},{"v":5.41528384207002e-07,"d":"0.00"},{"v":3.67797237273654e-05,"d":"0.00"},"up","yes"]
[161106,"j","chr5","-",172767136,172771251,"MSTRG.12537.1",2,3674,"MSTRG.12537","DUSP1","NA","NA","NA","NA","NA",{"v":3.462265,"d":"3.46"},{"v":44.604988,"d":"44.60"},{"v":0.0776205791155016,"d":"0.08"},{"v":-3.68741699287984,"d":"-3.69"},{"v":5.48367065906346e-07,"d":"0.00"},{"v":3.71179443119251E-5,"d":"0.00"},"down","yes"]
[200499,0,"chrX","+",147911951,147951112,"ENST00000218200",16,4333,"MSTRG.15471","FMR1","GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0006397(mRNA processing);GO:0006810(transport);GO:0008380(RNA splicing);GO:0051028(mRNA transport);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005829(cytosol);GO:0030529(intracellular ribonucleoprotein complex);GO:0005694(chromosome);GO:0042803(protein homodimerization activity);GO:0005886(plasma membrane);GO:0042995(cell projection);GO:0005515(protein binding);GO:0006974(cellular response to DNA damage stimulus);GO:0048471(perinuclear region of cytoplasm);GO:0030054(cell junction);GO:0045202(synapse);GO:0045211(postsynaptic membrane);GO:0007399(nervous system development);GO:0005654(nucleoplasm);GO:0043022(ribosome binding);GO:0045727(positive regulation of translation);GO:0005730(nucleolus);GO:0031047(gene silencing by RNA);GO:0030425(dendrite);GO:0008017(microtubule binding);GO:0000775(chromosome, centromeric region);GO:0003729(mRNA binding);GO:0030424(axon);GO:0030426(growth cone);GO:0043204(perikaryon);GO:0098586(cellular response to virus);GO:0006417(regulation of translation);GO:0003682(chromatin binding);GO:0044325(ion channel binding);GO:0070840(dynein complex binding);GO:0042802(identical protein binding);GO:2000637(positive regulation of gene silencing by miRNA);GO:0005845(mRNA cap binding complex);GO:0014069(postsynaptic density);GO:0043197(dendritic spine);GO:0016032(viral process);GO:0043005(neuron projection);GO:0046982(protein heterodimerization activity);GO:0042734(presynaptic membrane);GO:0000381(regulation of alternative mRNA splicing, via spliceosome);GO:0003730(mRNA 3'-UTR binding);GO:0051491(positive regulation of filopodium assembly);GO:0031369(translation initiation factor binding);GO:0033592(RNA strand annealing activity);GO:0035613(RNA stem-loop binding);GO:0048027(mRNA 5'-UTR binding);GO:0036464(cytoplasmic ribonucleoprotein granule);GO:0035064(methylated histone binding);GO:1901386(negative regulation of voltage-gated calcium channel activity);GO:0032797(SMN complex);GO:0015030(Cajal body);GO:0030371(translation repressor activity);GO:0045947(negative regulation of translational initiation);GO:0060999(positive regulation of dendritic spine development);GO:0051489(regulation of filopodium assembly);GO:0005844(polysome);GO:0034644(cellular response to UV);GO:2001022(positive regulation of response to DNA damage stimulus);GO:0008266(poly(U) RNA binding);GO:0002092(positive regulation of receptor internalization);GO:0032433(filopodium tip);GO:0019897(extrinsic component of plasma membrane);GO:0043679(axon terminus);GO:0035198(miRNA binding);GO:0043488(regulation of mRNA stability);GO:0046928(regulation of neurotransmitter secretion);GO:0072711(cellular response to hydroxyurea);GO:0033129(positive regulation of histone phosphorylation);GO:0002151(G-quadruplex RNA binding);GO:0042788(polysomal ribosome);GO:0034046(poly(G) binding);GO:0098908(regulation of neuronal action potential);GO:0060998(regulation of dendritic spine development);GO:1990904(ribonucleoprotein complex);GO:0035197(siRNA binding);GO:1990825(sequence-specific mRNA binding);GO:0007215(glutamate receptor signaling pathway);GO:0044830(modulation by host of viral RNA genome replication);GO:0060964(regulation of gene silencing by miRNA);GO:1900453(negative regulation of long term synaptic depression);GO:1901254(positive regulation of intracellular transport of viral material);GO:1901800(positive regulation of proteasomal protein catabolic process);GO:1902373(negative regulation of mRNA catabolic process);GO:1902416(positive regulation of mRNA binding);GO:2000301(negative regulation of synaptic vesicle exocytosis);GO:2000766(negative regulation of cytoplasmic translation);GO:0010369(chromocenter);GO:0019034(viral replication complex);GO:0071598(neuronal ribonucleoprotein granule);GO:0097386(glial cell projection);GO:0098793(presynapse);GO:0098794(postsynapse);GO:1902737(dendritic filopodium);GO:1990124(messenger ribonucleoprotein complex);GO:1990812(growth cone filopodium)","03013(RNA transport)","K15516","NA","fragile X mental retardation 1 [Source:HGNC Symbol;Acc:HGNC:3775]",{"v":2.907066,"d":"2.91"},{"v":0.229897,"d":"0.23"},{"v":12.6450801880842,"d":"12.65"},{"v":3.6605042806892,"d":"3.66"},{"v":5.50505102718224e-07,"d":"0.00"},{"v":3.71367766590456E-5,"d":"0.00"},"up","yes"]
[110536,0,"chr2","-",69467787,69643717,"ENST00000409085",22,11345,"MSTRG.8788","AAK1","GO:0004672(protein kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0016020(membrane);GO:0000166(nucleotide binding);GO:0004674(protein serine/threonine kinase activity);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0005905(clathrin-coated pit);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0006897(endocytosis);GO:0031252(cell leading edge);GO:0050821(protein stabilization);GO:0061024(membrane organization);GO:0030136(clathrin-coated vesicle);GO:0046777(protein autophosphorylation);GO:0005112(Notch binding);GO:0045747(positive regulation of Notch signaling pathway);GO:0032880(regulation of protein localization);GO:0019897(extrinsic component of plasma membrane);GO:2000369(regulation of clathrin-dependent endocytosis);GO:0043195(terminal bouton);GO:0035612(AP-2 adaptor complex binding)","NA","NA","NA","AP2 associated kinase 1 [Source:HGNC Symbol;Acc:HGNC:19679]",{"v":0.06385,"d":"0.06"},{"v":0.899577,"d":"0.90"},{"v":0.0709778040123303,"d":"0.07"},{"v":-3.81648825033684,"d":"-3.82"},{"v":5.52852521317798e-07,"d":"0.00"},{"v":3.71695594130431e-05,"d":"0.00"},"down","yes"]
[96695,"j","chr19","-",11300542,11339668,"MSTRG.7821.1",7,5928,"MSTRG.7821","RAB3D","NA","NA","NA","NA","NA",{"v":0.751057,"d":"0.75"},{"v":9.782334,"d":"9.78"},{"v":0.0767768714501059,"d":"0.08"},{"v":-3.70318441619284,"d":"-3.70"},{"v":5.56559823108099e-07,"d":"0.00"},{"v":3.72932434490688e-05,"d":"0.00"},"down","yes"]
[170194,0,"chr6","-",151364117,151391548,"ENST00000325144",3,3090,"MSTRG.13345","ZBTB2","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:0001078(transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0000122(negative regulation of transcription from RNA polymerase II promoter)","NA","NA","NA","zinc finger and BTB domain containing 2 [Source:HGNC Symbol;Acc:HGNC:20868]",{"v":0.342514,"d":"0.34"},{"v":4.64507,"d":"4.65"},{"v":0.0737371019166557,"d":"0.07"},{"v":-3.76146547435508,"d":"-3.76"},{"v":5.93014808073727e-07,"d":"0.00"},{"v":3.9603075878315e-05,"d":"0.00"},"down","yes"]
[29549,0,"chr11","+",59142748,59155039,"ENST00000528737",5,6189,"ENSG00000166801","FAM111A","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0001650(fibrillar center);GO:0006260(DNA replication);GO:0051607(defense response to virus);GO:0005515(protein binding);GO:0045071(negative regulation of viral genome replication);GO:0016032(viral process);GO:0000785(chromatin)","NA","NA","NA","family with sequence similarity 111 member A [Source:HGNC Symbol;Acc:HGNC:24725]",{"v":0.141954,"d":"0.14"},{"v":1.953263,"d":"1.95"},{"v":0.0726753130530809,"d":"0.07"},{"v":-3.78239080890816,"d":"-3.78"},{"v":5.95202787653925e-07,"d":"0.00"},{"v":3.96166975462453e-05,"d":"0.00"},"down","yes"]
[26625,"j","chr11","-",10573587,10606281,"MSTRG.2251.5",10,4064,"MSTRG.2251","MRVI1","NA","NA","NA","NA","NA",{"v":1.362102,"d":"1.36"},{"v":17.523643,"d":"17.52"},{"v":0.0777293853795127,"d":"0.08"},{"v":-3.6853960811444,"d":"-3.69"},{"v":5.9986433140635e-07,"d":"0.00"},{"v":3.97943221578804e-05,"d":"0.00"},"down","yes"]
[36845,0,"chr11","-",128458761,128522310,"ENST00000535549",4,4594,"MSTRG.2965","ETS1","GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0005634(nucleus);GO:0050729(positive regulation of inflammatory response);GO:1904996(positive regulation of leukocyte adhesion to vascular endothelial cell);GO:0005737(cytoplasm);GO:0005654(nucleoplasm);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0043565(sequence-specific DNA binding);GO:0005515(protein binding);GO:0002376(immune system process);GO:0042802(identical protein binding);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:0006955(immune response);GO:0008134(transcription factor binding);GO:0045893(positive regulation of transcription, DNA-templated);GO:0000982(transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0001077(transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0008285(negative regulation of cell proliferation);GO:0010595(positive regulation of endothelial cell migration);GO:0045765(regulation of angiogenesis);GO:0048870(cell motility);GO:0035035(histone acetyltransferase binding);GO:1990837(sequence-specific double-stranded DNA binding);GO:0001666(response to hypoxia);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0007565(female pregnancy);GO:0008284(positive regulation of cell proliferation);GO:0009611(response to wounding);GO:0009612(response to mechanical stimulus);GO:0010715(regulation of extracellular matrix disassembly);GO:0021854(hypothalamus development);GO:0021983(pituitary gland development);GO:0030335(positive regulation of cell migration);GO:0030578(PML body organization);GO:0032355(response to estradiol);GO:0034616(response to laminar fluid shear stress);GO:0044849(estrous cycle);GO:0045648(positive regulation of erythrocyte differentiation);GO:0045766(positive regulation of angiogenesis);GO:0050728(negative regulation of inflammatory response);GO:0051272(positive regulation of cellular component movement);GO:0060055(angiogenesis involved in wound healing);GO:0061614(pri-miRNA transcription from RNA polymerase II promoter);GO:0070301(cellular response to hydrogen peroxide);GO:0070555(response to interleukin-1);GO:0005667(transcription factor complex)","04014(Ras signaling pathway);04218(Cellular senescence);05200(Pathways in cancer);05211(Renal cell carcinoma);05166(HTLV-I infection)","K02678","NA","ETS proto-oncogene 1, transcription factor [Source:HGNC Symbol;Acc:HGNC:3488]",{"v":5.578199,"d":"5.58"},{"v":0.460114,"d":"0.46"},{"v":12.1235150419244,"d":"12.12"},{"v":3.59973614339542,"d":"3.60"},{"v":6.07940928976324e-07,"d":"0.00"},{"v":4.01965710920504e-05,"d":"0.00"},"up","yes"]
[38171,0,"chr12","+",6946577,6961316,"ENST00000399448",16,2159,"MSTRG.3080","PTPN6","GO:0008284(positive regulation of cell proliferation);GO:0005737(cytoplasm);GO:0005634(nucleus);GO:0014068(positive regulation of phosphatidylinositol 3-kinase signaling);GO:0005730(nucleolus);GO:0016787(hydrolase activity);GO:0004725(protein tyrosine phosphatase activity);GO:0016791(phosphatase activity);GO:0006470(protein dephosphorylation);GO:0016311(dephosphorylation);GO:0035335(peptidyl-tyrosine dephosphorylation);GO:0004721(phosphoprotein phosphatase activity);GO:0005515(protein binding);GO:0030154(cell differentiation);GO:0050900(leukocyte migration);GO:0005576(extracellular region);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0019901(protein kinase binding);GO:0008285(negative regulation of cell proliferation);GO:0008283(cell proliferation);GO:0043234(protein complex);GO:0043312(neutrophil degranulation);GO:0007186(G-protein coupled receptor signaling pathway);GO:0006915(apoptotic process);GO:0030168(platelet activation);GO:0016020(membrane);GO:0035580(specific granule lumen);GO:1904724(tertiary granule lumen);GO:0031295(T cell costimulation);GO:0070372(regulation of ERK1 and ERK2 cascade);GO:0018108(peptidyl-tyrosine phosphorylation);GO:0060338(regulation of type I interferon-mediated signaling pathway);GO:0050732(negative regulation of peptidyl-tyrosine phosphorylation);GO:0005001(transmembrane receptor protein tyrosine phosphatase activity);GO:2000045(regulation of G1/S transition of mitotic cell cycle);GO:0001784(phosphotyrosine residue binding);GO:0017124(SH3 domain binding);GO:0042169(SH2 domain binding);GO:0050839(cell adhesion molecule binding);GO:0002244(hematopoietic progenitor cell differentiation);GO:0002924(negative regulation of humoral immune response mediated by circulating immunoglobulin);GO:0030220(platelet formation);GO:0033277(abortive mitotic cell cycle);GO:0033630(positive regulation of cell adhesion mediated by integrin);GO:0035556(intracellular signal transduction);GO:0035855(megakaryocyte development);GO:0042130(negative regulation of T cell proliferation);GO:0042267(natural killer cell mediated cytotoxicity);GO:0043407(negative regulation of MAP kinase activity);GO:0043409(negative regulation of MAPK cascade);GO:0045577(regulation of B cell differentiation);GO:0050853(B cell receptor signaling pathway);GO:0050859(negative regulation of B cell receptor signaling pathway);GO:0050860(negative regulation of T cell receptor signaling pathway);GO:0051279(regulation of release of sequestered calcium ion into cytosol);GO:0070527(platelet aggregation);GO:0005911(cell-cell junction);GO:0042105(alpha-beta T cell receptor complex)","04630(Jak-STAT signaling pathway);04520(Adherens junction);04650(Natural killer cell mediated cytotoxicity);04660(T cell receptor signaling pathway);04662(B cell receptor signaling pathway);05205(Proteoglycans in cancer);05140(Leishmaniasis)","K05697","EC:3.1.3.48","protein tyrosine phosphatase, non-receptor type 6 [Source:HGNC Symbol;Acc:HGNC:9658]",{"v":1.53534,"d":"1.54"},{"v":19.804895,"d":"19.80"},{"v":0.0775232587701172,"d":"0.08"},{"v":-3.68922697257344,"d":"-3.69"},{"v":6.29922244721956e-07,"d":"0.00"},{"v":4.15124996125677e-05,"d":"0.00"},"down","yes"]
[48049,0,"chr12","+",123383773,123409358,"ENST00000402868",8,3140,"ENSG00000183955","KMT5A","GO:0005634(nucleus);GO:0005829(cytosol);GO:0008168(methyltransferase activity);GO:0016740(transferase activity);GO:0032259(methylation);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0016569(covalent chromatin modification);GO:0051301(cell division);GO:0005694(chromosome);GO:0005515(protein binding);GO:0007049(cell cycle);GO:0018024(histone-lysine N-methyltransferase activity);GO:0018026(peptidyl-lysine monomethylation);GO:0016279(protein-lysine N-methyltransferase activity);GO:0034968(histone lysine methylation);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0003714(transcription corepressor activity);GO:0005654(nucleoplasm);GO:0045892(negative regulation of transcription, DNA-templated);GO:1901796(regulation of signal transduction by p53 class mediator);GO:0002039(p53 binding);GO:0042799(histone methyltransferase activity (H4-K20 specific));GO:0016278(lysine N-methyltransferase activity);GO:0034770(histone H4-K20 methylation);GO:0043516(regulation of DNA damage response, signal transduction by p53 class mediator)","00310(Lysine degradation)","K11428","EC:2.1.1.43","lysine methyltransferase 5A [Source:HGNC Symbol;Acc:HGNC:29489]",{"v":0.197963,"d":"0.20"},{"v":2.761051,"d":"2.76"},{"v":0.0716984220863722,"d":"0.07"},{"v":-3.80191482082265,"d":"-3.80"},{"v":6.46093013496162e-07,"d":"0.00"},{"v":4.24381095180637e-05,"d":"0.00"},"down","yes"]
[71438,0,"chr16","+",28985096,28990773,"ENST00000395456",12,1616,"MSTRG.5787","LAT","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0007165(signal transduction);GO:0009967(positive regulation of signal transduction);GO:0005886(plasma membrane);GO:0043547(positive regulation of GTPase activity);GO:0005515(protein binding);GO:0002376(immune system process);GO:0002250(adaptive immune response);GO:0038095(Fc-epsilon receptor signaling pathway);GO:0042629(mast cell granule);GO:0019901(protein kinase binding);GO:0008180(COP9 signalosome);GO:0000165(MAPK cascade);GO:0050852(T cell receptor signaling pathway);GO:0030168(platelet activation);GO:0042110(T cell activation);GO:0043303(mast cell degranulation);GO:0005088(Ras guanyl-nucleotide exchange factor activity);GO:0005070(SH3/SH2 adaptor activity);GO:0002260(lymphocyte homeostasis);GO:0006954(inflammatory response);GO:0006955(immune response);GO:0007229(integrin-mediated signaling pathway);GO:0007265(Ras protein signal transduction);GO:0010467(gene expression);GO:0019722(calcium-mediated signaling);GO:0035556(intracellular signal transduction);GO:0045860(positive regulation of protein kinase activity);GO:0048872(homeostasis of number of cells);GO:0050863(regulation of T cell activation);GO:0001772(immunological synapse);GO:0005911(cell-cell junction);GO:0045121(membrane raft)","04014(Ras signaling pathway);04015(Rap1 signaling pathway);04064(NF-kappa B signaling pathway);04650(Natural killer cell mediated cytotoxicity);04660(T cell receptor signaling pathway);04658(Th1 and Th2 cell differentiation);04659(Th17 cell differentiation);04664(Fc epsilon RI signaling pathway);04666(Fc gamma R-mediated phagocytosis)","K07362","NA","linker for activation of T-cells [Source:HGNC Symbol;Acc:HGNC:18874]",{"v":1.580615,"d":"1.58"},{"v":20.341576,"d":"20.34"},{"v":0.077703664652139,"d":"0.08"},{"v":-3.68587354930398,"d":"-3.69"},{"v":6.79620272841282e-07,"d":"0.00"},{"v":4.44526087254493E-5,"d":"0.00"},"down","yes"]
[72163,0,"chr16","+",31117664,31131389,"ENST00000219797",11,1525,"MSTRG.5882","KAT8","GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0005654(nucleoplasm);GO:0016740(transferase activity);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0016569(covalent chromatin modification);GO:0016746(transferase activity, transferring acyl groups);GO:0005694(chromosome);GO:0005515(protein binding);GO:0016747(transferase activity, transferring acyl groups other than amino-acyl groups);GO:0004402(histone acetyltransferase activity);GO:0045893(positive regulation of transcription, DNA-templated);GO:0008134(transcription factor binding);GO:0045892(negative regulation of transcription, DNA-templated);GO:0071339(MLL1 complex);GO:0035064(methylated histone binding);GO:0043995(histone acetyltransferase activity (H4-K5 specific));GO:0043996(histone acetyltransferase activity (H4-K8 specific));GO:0046972(histone acetyltransferase activity (H4-K16 specific));GO:0043981(histone H4-K5 acetylation);GO:0043982(histone H4-K8 acetylation);GO:0043984(histone H4-K16 acetylation);GO:0000123(histone acetyltransferase complex);GO:0010506(regulation of autophagy);GO:0030099(myeloid cell differentiation);GO:0016407(acetyltransferase activity);GO:0072487(MSL complex);GO:0016573(histone acetylation);GO:0019899(enzyme binding);GO:0000776(kinetochore)","NA","NA","NA","lysine acetyltransferase 8 [Source:HGNC Symbol;Acc:HGNC:17933]",{"v":10.309479,"d":"10.31"},{"v":0.848228,"d":"0.85"},{"v":12.1541366236436,"d":"12.15"},{"v":3.60337550918965,"d":"3.60"},{"v":6.81214857271008e-07,"d":"0.00"},{"v":4.44526087254493E-5,"d":"0.00"},"up","yes"]
[191451,0,"chr9","-",86264546,86282529,"ENST00000375991",4,1958,"MSTRG.14822","ISCA1","GO:0046872(metal ion binding);GO:0005198(structural molecule activity);GO:0005739(mitochondrion);GO:0051536(iron-sulfur cluster binding);GO:0097428(protein maturation by iron-sulfur cluster transfer);GO:0005759(mitochondrial matrix);GO:0044281(small molecule metabolic process);GO:0008198(ferrous iron binding);GO:0016226(iron-sulfur cluster assembly);GO:0051537(2 iron, 2 sulfur cluster binding)","NA","NA","NA","iron-sulfur cluster assembly 1 [Source:HGNC Symbol;Acc:HGNC:28660]",{"v":1.16772,"d":"1.17"},{"v":15.010691,"d":"15.01"},{"v":0.0777925546532135,"d":"0.08"},{"v":-3.68422410498595,"d":"-3.68"},{"v":6.92147016652987e-07,"d":"0.00"},{"v":4.50188652395011e-05,"d":"0.00"},"down","yes"]
[11831,0,"chr1","+",155689058,155739010,"ENST00000368336",13,2089,"MSTRG.1064","DAP3","GO:0003723(RNA binding);GO:0000166(nucleotide binding);GO:0005654(nucleoplasm);GO:0005739(mitochondrion);GO:0030529(intracellular ribonucleoprotein complex);GO:0005840(ribosome);GO:0005525(GTP binding);GO:0015935(small ribosomal subunit);GO:0006915(apoptotic process);GO:0005515(protein binding);GO:0005761(mitochondrial ribosome);GO:0003735(structural constituent of ribosome);GO:0005763(mitochondrial small ribosomal subunit);GO:0005743(mitochondrial inner membrane);GO:0070125(mitochondrial translational elongation);GO:0070126(mitochondrial translational termination);GO:0097190(apoptotic signaling pathway)","NA","NA","NA","death associated protein 3 [Source:HGNC Symbol;Acc:HGNC:2673]",{"v":5.714018,"d":"5.71"},{"v":0.468034,"d":"0.47"},{"v":12.2085532247657,"d":"12.21"},{"v":3.6098203386913,"d":"3.61"},{"v":7.16244148296956e-07,"d":"0.00"},{"v":4.64349453025766e-05,"d":"0.00"},"up","yes"]
[31890,0,"chr11","+",67289348,67302483,"ENST00000308440",16,2219,"MSTRG.2599","ANKRD13D","GO:0016020(membrane);GO:0005886(plasma membrane);GO:0005737(cytoplasm);GO:0005768(endosome);GO:0005770(late endosome)","NA","NA","NA","ankyrin repeat domain 13D [Source:HGNC Symbol;Acc:HGNC:27880]",{"v":0.293973,"d":"0.29"},{"v":3.991685,"d":"3.99"},{"v":0.0736463423341271,"d":"0.07"},{"v":-3.76324231458085,"d":"-3.76"},{"v":7.20924734772628e-07,"d":"0.00"},{"v":4.65871362587049e-05,"d":"0.00"},"down","yes"]
[100986,0,"chr19","-",38409840,38426162,"ENST00000587738",17,2293,"MSTRG.8106","RASGRP4","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0007264(small GTPase mediated signal transduction);GO:0046872(metal ion binding);GO:0035556(intracellular signal transduction);GO:0005509(calcium ion binding);GO:0005886(plasma membrane);GO:0043547(positive regulation of GTPase activity);GO:0030154(cell differentiation);GO:0005085(guanyl-nucleotide exchange factor activity);GO:0005829(cytosol);GO:0000165(MAPK cascade);GO:0008283(cell proliferation);GO:0005088(Ras guanyl-nucleotide exchange factor activity);GO:0007169(transmembrane receptor protein tyrosine kinase signaling pathway);GO:0030742(GTP-dependent protein binding);GO:0016049(cell growth);GO:0046579(positive regulation of Ras protein signal transduction);GO:0008277(regulation of G-protein coupled receptor protein signaling pathway);GO:0019992(diacylglycerol binding);GO:0007202(activation of phospholipase C activity);GO:0030099(myeloid cell differentiation);GO:0009991(response to extracellular stimulus);GO:0005622(intracellular)","04014(Ras signaling pathway);04010(MAPK signaling pathway);05200(Pathways in cancer)","NA","NA","RAS guanyl releasing protein 4 [Source:HGNC Symbol;Acc:HGNC:18958]",{"v":0.948596,"d":"0.95"},{"v":12.167386,"d":"12.17"},{"v":0.0779621851398484,"d":"0.08"},{"v":-3.68108166246467,"d":"-3.68"},{"v":7.23980716432507e-07,"d":"0.00"},{"v":4.66336998249171e-05,"d":"0.00"},"down","yes"]
[7759,0,"chr1","+",86704570,86748176,"ENST00000535010",8,6227,"MSTRG.676","SH3GLB1","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005829(cytosol);GO:0005794(Golgi apparatus);GO:0005739(mitochondrion);GO:0005515(protein binding);GO:0006915(apoptotic process);GO:0000139(Golgi membrane);GO:0005741(mitochondrial outer membrane);GO:0006914(autophagy);GO:0031410(cytoplasmic vesicle);GO:0030496(midbody);GO:0042802(identical protein binding);GO:0008289(lipid binding);GO:0045296(cadherin binding);GO:0070062(extracellular exosome);GO:0010508(positive regulation of autophagy);GO:0000421(autophagosome membrane);GO:0051259(protein oligomerization);GO:1903955(positive regulation of protein targeting to mitochondrion);GO:0032461(positive regulation of protein oligomerization);GO:0016241(regulation of macroautophagy);GO:0042149(cellular response to glucose starvation);GO:0032465(regulation of cytokinesis);GO:0031647(regulation of protein stability);GO:0034198(cellular response to amino acid starvation);GO:0042803(protein homodimerization activity);GO:2000786(positive regulation of autophagosome assembly);GO:0032801(receptor catabolic process);GO:0048102(autophagic cell death);GO:0090148(membrane fission);GO:1903527(positive regulation of membrane tubulation);GO:1903778(protein localization to vacuolar membrane);GO:0005504(fatty acid binding);GO:0042171(lysophosphatidic acid acyltransferase activity);GO:0006654(phosphatidic acid biosynthetic process);GO:0008654(phospholipid biosynthetic process);GO:0043552(positive regulation of phosphatidylinositol 3-kinase activity);GO:0051084('de novo' posttranslational protein folding);GO:1900740(positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway);GO:0043234(protein complex)","04144(Endocytosis);04140(Autophagy - animal)","K11248","NA","SH3 domain containing GRB2 like, endophilin B1 [Source:HGNC Symbol;Acc:HGNC:10833]",{"v":0.38965,"d":"0.39"},{"v":4.977833,"d":"4.98"},{"v":0.078277033399875,"d":"0.08"},{"v":-3.67526710908324,"d":"-3.68"},{"v":7.26483382364571e-07,"d":"0.00"},{"v":4.66444378747773e-05,"d":"0.00"},"down","yes"]
[54543,0,"chr14","+",39267411,39350421,"ENST00000556148",24,2526,"MSTRG.4340","CTAGE5","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0070971(endoplasmic reticulum exit site);GO:0043085(positive regulation of catalytic activity);GO:0005515(protein binding);GO:0006888(ER to Golgi vesicle-mediated transport);GO:0008047(enzyme activator activity);GO:0032527(protein exit from endoplasmic reticulum);GO:0035459(cargo loading into vesicle);GO:0070973(protein localization to endoplasmic reticulum exit site)","NA","NA","NA","CTAGE family member 5, ER export factor [Source:HGNC Symbol;Acc:HGNC:7057]",{"v":0.246046,"d":"0.25"},{"v":3.375244,"d":"3.38"},{"v":0.072897248317455,"d":"0.07"},{"v":-3.77799183220038,"d":"-3.78"},{"v":7.4861244635565e-07,"d":"0.00"},{"v":4.79111965667616e-05,"d":"0.00"},"down","yes"]
[92907,0,"chr18","+",58671386,58754477,"ENST00000348428",17,9368,"MSTRG.7537","MALT1","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005730(nucleolus);GO:0005829(cytosol);GO:0016787(hydrolase activity);GO:0001650(fibrillar center);GO:0016567(protein ubiquitination);GO:0005515(protein binding);GO:0008233(peptidase activity);GO:0006508(proteolysis);GO:0004871(signal transducer activity);GO:0048471(perinuclear region of cytoplasm);GO:0004197(cysteine-type endopeptidase activity);GO:0051092(positive regulation of NF-kappaB transcription factor activity);GO:0038095(Fc-epsilon receptor signaling pathway);GO:0005886(plasma membrane);GO:0006952(defense response);GO:0002223(stimulatory C-type lectin receptor signaling pathway);GO:0050852(T cell receptor signaling pathway);GO:0050870(positive regulation of T cell activation);GO:0043234(protein complex);GO:0043123(positive regulation of I-kappaB kinase/NF-kappaB signaling);GO:0043066(negative regulation of apoptotic process);GO:0007250(activation of NF-kappaB-inducing kinase activity);GO:0004842(ubiquitin-protein transferase activity);GO:0042981(regulation of apoptotic process);GO:0051259(protein oligomerization);GO:0043621(protein self-association);GO:0031398(positive regulation of protein ubiquitination);GO:0002726(positive regulation of T cell cytokine production);GO:0032743(positive regulation of interleukin-2 production);GO:0051168(nuclear export);GO:0019209(kinase activator activity);GO:0032449(CBM complex);GO:0002020(protease binding);GO:0001923(B-1 B cell differentiation);GO:0002237(response to molecule of bacterial origin);GO:0009620(response to fungus);GO:0042098(T cell proliferation);GO:0042113(B cell activation);GO:0045087(innate immune response);GO:0050856(regulation of T cell receptor signaling pathway)","04064(NF-kappa B signaling pathway);04660(T cell receptor signaling pathway);04662(B cell receptor signaling pathway);05152(Tuberculosis)","K07369","EC:3.4.22.-","MALT1 paracaspase [Source:HGNC Symbol;Acc:HGNC:6819]",{"v":2.80727,"d":"2.81"},{"v":0.239285,"d":"0.24"},{"v":11.7319096474915,"d":"11.73"},{"v":3.55236596031939,"d":"3.55"},{"v":7.82290536650003e-07,"d":"0.00"},{"v":4.9906637175167e-05,"d":"0.00"},"up","yes"]
[49537,0,"chr13","-",32516894,32525579,"ENST00000503814",2,5317,"MSTRG.3943","N4BP2L2","GO:0005634(nucleus);GO:0005515(protein binding);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0003674(molecular_function);GO:0070062(extracellular exosome);GO:0019899(enzyme binding);GO:0017053(transcriptional repressor complex);GO:0001106(RNA polymerase II transcription corepressor activity);GO:1902035(positive regulation of hematopoietic stem cell proliferation);GO:1902037(negative regulation of hematopoietic stem cell differentiation)","NA","NA","NA","NEDD4 binding protein 2 like 2 [Source:HGNC Symbol;Acc:HGNC:26916]",{"v":1.819622,"d":"1.82"},{"v":0.149626,"d":"0.15"},{"v":12.1611350968415,"d":"12.16"},{"v":3.6042059883199,"d":"3.60"},{"v":8.06255728025835e-07,"d":"0.00"},{"v":5.12717018382799E-5,"d":"0.00"},"up","yes"]
[182687,0,"chr8","-",30063012,30083208,"ENST00000545648",5,1976,"MSTRG.14272","SARAF","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0006811(ion transport);GO:0006816(calcium ion transport);GO:0030176(integral component of endoplasmic reticulum membrane);GO:0005515(protein binding);GO:2001256(regulation of store-operated calcium entry)","NA","NA","NA","store-operated calcium entry associated regulatory factor [Source:HGNC Symbol;Acc:HGNC:28789]",{"v":2.07756,"d":"2.08"},{"v":25.963453,"d":"25.96"},{"v":0.0800186323444728,"d":"0.08"},{"v":-3.64352021901059,"d":"-3.64"},{"v":8.09250186668379e-07,"d":"0.00"},{"v":5.12987546901403e-05,"d":"0.00"},"down","yes"]
[111349,0,"chr2","-",74526648,74529939,"ENST00000377526",12,1695,"MSTRG.8842","AUP1","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0050790(regulation of catalytic activity);GO:0005515(protein binding);GO:0030970(retrograde protein transport, ER to cytosol);GO:0070062(extracellular exosome);GO:0030176(integral component of endoplasmic reticulum membrane);GO:0043130(ubiquitin binding);GO:0030433(ubiquitin-dependent ERAD pathway);GO:0097027(ubiquitin-protein transferase activator activity);GO:0000839(Hrd1p ubiquitin ligase ERAD-L complex)","NA","NA","NA","ancient ubiquitous protein 1 [Source:HGNC Symbol;Acc:HGNC:891]",{"v":0.781793,"d":"0.78"},{"v":10.12833,"d":"10.13"},{"v":0.0771887369388636,"d":"0.08"},{"v":-3.69546583901575,"d":"-3.70"},{"v":8.19538329066125e-07,"d":"0.00"},{"v":5.17865232746594e-05,"d":"0.00"},"down","yes"]
[73423,"j","chr16","+",57040650,57083520,"MSTRG.5947.17",33,3720,"MSTRG.5947","NLRC5","NA","NA","NA","NA","NA",{"v":7.425855,"d":"7.43"},{"v":0.640188,"d":"0.64"},{"v":11.5994910869932,"d":"11.60"},{"v":3.5359896052077,"d":"3.54"},{"v":8.36603001671511e-07,"d":"0.00"},{"v":5.26980717267405e-05,"d":"0.00"},"up","yes"]
[33850,"j","chr11","-",85957559,86068871,"MSTRG.2788.3",20,3522,"MSTRG.2788","PICALM","NA","NA","NA","NA","NA",{"v":3.627811,"d":"3.63"},{"v":44.40765,"d":"44.41"},{"v":0.0816933794064761,"d":"0.08"},{"v":-3.61363702553437,"d":"-3.61"},{"v":8.56170250835933e-07,"d":"0.00"},{"v":5.3637108588857e-05,"d":"0.00"},"down","yes"]
[90615,0,"chr18","-",9546791,9614569,"ENST00000400555",20,3885,"MSTRG.7416","PPP4R1","GO:0007165(signal transduction);GO:0004721(phosphoprotein phosphatase activity);GO:0005515(protein binding);GO:0050790(regulation of catalytic activity);GO:0019888(protein phosphatase regulator activity);GO:0006470(protein dephosphorylation);GO:0030289(protein phosphatase 4 complex);GO:0006468(protein phosphorylation)","NA","NA","NA","protein phosphatase 4 regulatory subunit 1 [Source:HGNC Symbol;Acc:HGNC:9320]",{"v":0.428392,"d":"0.43"},{"v":5.437607,"d":"5.44"},{"v":0.0787831853239853,"d":"0.08"},{"v":-3.66596844128919,"d":"-3.67"},{"v":8.56882894623668e-07,"d":"0.00"},{"v":5.3637108588857e-05,"d":"0.00"},"down","yes"]
[38897,"j","chr12","-",10699555,10723338,"MSTRG.3174.7",9,1270,"MSTRG.3174","YBX3","NA","NA","NA","NA","NA",{"v":2.061084,"d":"2.06"},{"v":25.730995,"d":"25.73"},{"v":0.0801012164512099,"d":"0.08"},{"v":-3.64203203759265,"d":"-3.64"},{"v":8.6431704828897e-07,"d":"0.00"},{"v":5.39333838132317e-05,"d":"0.00"},"down","yes"]
[134558,0,"chr3","+",33798571,33869707,"ENST00000457054",18,5962,"MSTRG.10793","PDCD6IP","GO:0006810(transport);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0015031(protein transport);GO:0005829(cytosol);GO:0051301(cell division);GO:0042803(protein homodimerization activity);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0042470(melanosome);GO:0007049(cell cycle);GO:0006915(apoptotic process);GO:0030054(cell junction);GO:0005925(focal adhesion);GO:0005815(microtubule organizing center);GO:0030496(midbody);GO:0005923(bicellular tight junction);GO:0070062(extracellular exosome);GO:0048306(calcium-dependent protein binding);GO:0019058(viral life cycle);GO:0036258(multivesicular body assembly);GO:0039702(viral budding via host ESCRT complex);GO:0016032(viral process);GO:1903543(positive regulation of exosomal secretion);GO:1903553(positive regulation of extracellular exosome assembly);GO:1903561(extracellular vesicle);GO:0000281(mitotic cytokinesis);GO:0070971(endoplasmic reticulum exit site);GO:0051260(protein homooligomerization);GO:0070830(bicellular tight junction assembly);GO:0010824(regulation of centrosome duplication);GO:0000920(cell separation after cytokinesis);GO:0045199(maintenance of epithelial cell apical/basal polarity);GO:0090611(ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway);GO:0090543(Flemming body);GO:0001772(immunological synapse);GO:0031871(proteinase activated receptor binding);GO:0042641(actomyosin);GO:0046755(viral budding);GO:0000915(actomyosin contractile ring assembly);GO:0090559(regulation of membrane permeability);GO:1903551(regulation of extracellular exosome assembly);GO:0046983(protein dimerization activity);GO:0043209(myelin sheath)","04144(Endocytosis)","K12200","NA","programmed cell death 6 interacting protein [Source:HGNC Symbol;Acc:HGNC:8766]",{"v":4.701329,"d":"4.70"},{"v":0.4083,"d":"0.41"},{"v":11.5143987264266,"d":"11.51"},{"v":3.5253671714935,"d":"3.53"},{"v":8.76903805518583e-07,"d":"0.00"},{"v":5.45483339208569e-05,"d":"0.00"},"up","yes"]
[48473,0,"chr12","+",130872070,130876281,"ENST00000392369",6,1530,"MSTRG.3872","RAN","GO:0003723(RNA binding);GO:0006810(transport);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0006886(intracellular protein transport);GO:0015031(protein transport);GO:0005525(GTP binding);GO:0000166(nucleotide binding);GO:0007165(signal transduction);GO:0003924(GTPase activity);GO:0051301(cell division);GO:0006913(nucleocytoplasmic transport);GO:0005515(protein binding);GO:0042470(melanosome);GO:0007049(cell cycle);GO:0003713(transcription coactivator activity);GO:0045893(positive regulation of transcription, DNA-templated);GO:0005643(nuclear pore);GO:0005654(nucleoplasm);GO:0005730(nucleolus);GO:0030496(midbody);GO:0005829(cytosol);GO:0045296(cadherin binding);GO:0070062(extracellular exosome);GO:0005814(centriole);GO:0075733(intracellular transport of virus);GO:0043657(host cell);GO:0003682(chromatin binding);GO:0016032(viral process);GO:0055037(recycling endosome);GO:0031012(extracellular matrix);GO:0007052(mitotic spindle organization);GO:0019003(GDP binding);GO:0000785(chromatin);GO:0043234(protein complex);GO:0045540(regulation of cholesterol biosynthetic process);GO:0030521(androgen receptor signaling pathway);GO:0005635(nuclear envelope);GO:0000278(mitotic cell cycle);GO:0032092(positive regulation of protein binding);GO:0046982(protein heterodimerization activity);GO:0000055(ribosomal large subunit export from nucleus);GO:0000056(ribosomal small subunit export from nucleus);GO:0060964(regulation of gene silencing by miRNA);GO:0006409(tRNA export from nucleus);GO:0000287(magnesium ion binding);GO:0050681(androgen receptor binding);GO:0070883(pre-miRNA binding);GO:0010586(miRNA metabolic process);GO:0006259(DNA metabolic process);GO:0000060(protein import into nucleus, translocation);GO:0006611(protein export from nucleus);GO:0005487(nucleocytoplasmic transporter activity);GO:0006606(protein import into nucleus);GO:0090631(pre-miRNA transporter activity);GO:0035281(pre-miRNA export from nucleus);GO:1902570(protein localization to nucleolus);GO:0042565(RNA nuclear export complex)","03013(RNA transport);03008(Ribosome biogenesis in eukaryotes);05166(HTLV-I infection);05169(Epstein-Barr virus infection)","NA","NA","RAN, member RAS oncogene family [Source:HGNC Symbol;Acc:HGNC:9846]",{"v":14.777333,"d":"14.78"},{"v":1.271946,"d":"1.27"},{"v":11.6178933696871,"d":"11.62"},{"v":3.53827658870428,"d":"3.54"},{"v":8.81301400528333e-07,"d":"0.00"},{"v":5.46516346762415e-05,"d":"0.00"},"up","yes"]
[546,0,"chr1","-",1663782,1670139,"ENST00000480991",3,2860,"MSTRG.73","SLC35E2B","GO:0016020(membrane);GO:0016021(integral component of membrane)","NA","NA","NA","solute carrier family 35 member E2B [Source:HGNC Symbol;Acc:HGNC:33941]",{"v":0.223894,"d":"0.22"},{"v":2.972817,"d":"2.97"},{"v":0.0753137512332579,"d":"0.08"},{"v":-3.73094288497353,"d":"-3.73"},{"v":8.8789963080518e-07,"d":"0.00"},{"v":5.47790601410252e-05,"d":"0.00"},"down","yes"]
[124445,0,"chr20","-",47657406,47786616,"ENST00000484875",21,4238,"MSTRG.9802","SULF2","GO:0040037(negative regulation of fibroblast growth factor receptor signaling pathway);GO:0046872(metal ion binding);GO:0016787(hydrolase activity);GO:0005509(calcium ion binding);GO:0003824(catalytic activity);GO:0005794(Golgi apparatus);GO:0008152(metabolic process);GO:0005783(endoplasmic reticulum);GO:0005886(plasma membrane);GO:0005615(extracellular space);GO:0008484(sulfuric ester hydrolase activity);GO:0009986(cell surface);GO:0008449(N-acetylglucosamine-6-sulfatase activity);GO:0005795(Golgi stack);GO:0051216(cartilage development);GO:0001822(kidney development);GO:0032836(glomerular basement membrane development);GO:0048706(embryonic skeletal system development);GO:0030177(positive regulation of Wnt signaling pathway);GO:0003094(glomerular filtration);GO:0010575(positive regulation of vascular endothelial growth factor production);GO:0004065(arylsulfatase activity);GO:0002063(chondrocyte development);GO:0009611(response to wounding);GO:0014846(esophagus smooth muscle contraction);GO:0030201(heparan sulfate proteoglycan metabolic process);GO:0035413(positive regulation of catenin import into nucleus);GO:0035860(glial cell-derived neurotrophic factor receptor signaling pathway);GO:0060348(bone development);GO:0060384(innervation);GO:0090263(positive regulation of canonical Wnt signaling pathway);GO:0097421(liver regeneration);GO:2000345(regulation of hepatocyte proliferation)","NA","NA","NA","sulfatase 2 [Source:HGNC Symbol;Acc:HGNC:20392]",{"v":1.171875,"d":"1.17"},{"v":14.421596,"d":"14.42"},{"v":0.0812583433900104,"d":"0.08"},{"v":-3.62134023706123,"d":"-3.62"},{"v":8.88842922961347e-07,"d":"0.00"},{"v":5.47790601410252e-05,"d":"0.00"},"down","yes"]
[111197,0,"chr2","-",74361156,74391867,"ENST00000434055",27,4229,"MSTRG.8832","DCTN1","GO:0006810(transport);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005829(cytosol);GO:0051301(cell division);GO:0005813(centrosome);GO:0015629(actin cytoskeleton);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0007049(cell cycle);GO:0007399(nervous system development);GO:0005874(microtubule);GO:0003774(motor activity);GO:0008017(microtubule binding);GO:0000922(spindle pole);GO:0005815(microtubule organizing center);GO:0005819(spindle);GO:0000776(kinetochore);GO:0005869(dynactin complex);GO:0030286(dynein complex);GO:0005814(centriole);GO:0005938(cell cortex);GO:0042147(retrograde transport, endosome to Golgi);GO:0000086(G2/M transition of mitotic cell cycle);GO:0010389(regulation of G2/M transition of mitotic cell cycle);GO:0097711(ciliary basal body docking);GO:0070840(dynein complex binding);GO:0010970(transport along microtubule);GO:0019886(antigen processing and presentation of exogenous peptide antigen via MHC class II);GO:0006888(ER to Golgi vesicle-mediated transport);GO:0015631(tubulin binding);GO:0005635(nuclear envelope);GO:0036498(IRE1-mediated unfolded protein response);GO:0000132(establishment of mitotic spindle orientation);GO:0000278(mitotic cell cycle);GO:0099738(cell cortex region);GO:0030904(retromer complex);GO:0031116(positive regulation of microtubule polymerization);GO:0090063(positive regulation of microtubule nucleation);GO:0035371(microtubule plus-end);GO:0060236(regulation of mitotic spindle organization);GO:0051081(nuclear envelope disassembly);GO:0010457(centriole-centriole cohesion);GO:0032402(melanosome transport);GO:0034454(microtubule anchoring at centrosome);GO:1905515(non-motile cilium assembly);GO:0031252(cell leading edge);GO:0043234(protein complex)","04962(Vasopressin-regulated water reabsorption);05016(Huntington's disease)","K04648","NA","dynactin subunit 1 [Source:HGNC Symbol;Acc:HGNC:2711]",{"v":3.371756,"d":"3.37"},{"v":0.28462,"d":"0.28"},{"v":11.8465181645703,"d":"11.85"},{"v":3.56639119073419,"d":"3.57"},{"v":8.93603188036089e-07,"d":"0.00"},{"v":5.49029798729373e-05,"d":"0.00"},"up","yes"]
[10822,0,"chr1","-",151291797,151327715,"ENST00000368874",11,3934,"MSTRG.951","PI4KB","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0005794(Golgi apparatus);GO:0005783(endoplasmic reticulum);GO:0005739(mitochondrion);GO:0005515(protein binding);GO:0000139(Golgi membrane);GO:0048471(perinuclear region of cytoplasm);GO:0005741(mitochondrial outer membrane);GO:0046854(phosphatidylinositol phosphorylation);GO:0048015(phosphatidylinositol-mediated signaling);GO:0005829(cytosol);GO:0012505(endomembrane system);GO:0004430(1-phosphatidylinositol 4-kinase activity);GO:0007165(signal transduction);GO:0006661(phosphatidylinositol biosynthetic process);GO:0030867(rough endoplasmic reticulum membrane);GO:0071889(14-3-3 protein binding);GO:0005768(endosome);GO:0006898(receptor-mediated endocytosis);GO:0005622(intracellular)","00562(Inositol phosphate metabolism);04070(Phosphatidylinositol signaling system)","K19801","EC:2.7.1.67","phosphatidylinositol 4-kinase beta [Source:HGNC Symbol;Acc:HGNC:8984]",{"v":0.183247,"d":"0.18"},{"v":2.449742,"d":"2.45"},{"v":0.0748025710462571,"d":"0.07"},{"v":-3.74076833180166,"d":"-3.74"},{"v":9.02286831877124e-07,"d":"0.00"},{"v":5.52664523279829e-05,"d":"0.00"},"down","yes"]
[194149,0,"chr9","-",129887187,130043194,"ENST00000420781",16,5410,"MSTRG.15037","FNBP1","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0006897(endocytosis);GO:0005886(plasma membrane);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0031410(cytoplasmic vesicle);GO:0005905(clathrin-coated pit);GO:0005764(lysosome);GO:0042802(identical protein binding);GO:0008289(lipid binding);GO:0005829(cytosol);GO:0061024(membrane organization);GO:0005938(cell cortex)","NA","NA","NA","formin binding protein 1 [Source:HGNC Symbol;Acc:HGNC:17069]",{"v":5.390551,"d":"5.39"},{"v":0.469347,"d":"0.47"},{"v":11.4852145640645,"d":"11.49"},{"v":3.52170590394281,"d":"3.52"},{"v":9.05394575013071e-07,"d":"0.00"},{"v":5.52872136815321e-05,"d":"0.00"},"up","yes"]
[34667,0,"chr11","-",104942868,104956698,"ENST00000393150",9,1340,"MSTRG.2819","CASP4","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005829(cytosol);GO:0016787(hydrolase activity);GO:0042981(regulation of apoptotic process);GO:0005886(plasma membrane);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005739(mitochondrion);GO:0008233(peptidase activity);GO:0008234(cysteine-type peptidase activity);GO:0006508(proteolysis);GO:0005576(extracellular region);GO:0004197(cysteine-type endopeptidase activity);GO:0002376(immune system process);GO:0045087(innate immune response);GO:0006954(inflammatory response);GO:0050700(CARD domain binding);GO:0043234(protein complex);GO:0006915(apoptotic process);GO:0012501(programmed cell death);GO:0070059(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress);GO:0050727(regulation of inflammatory response);GO:1903265(positive regulation of tumor necrosis factor-mediated signaling pathway);GO:0097153(cysteine-type endopeptidase activity involved in apoptotic process);GO:0072557(IPAF inflammasome complex);GO:0097193(intrinsic apoptotic signaling pathway);GO:1904646(cellular response to amyloid-beta);GO:0061702(inflammasome complex);GO:0072559(NLRP3 inflammasome complex);GO:0097169(AIM2 inflammasome complex)","04621(NOD-like receptor signaling pathway)","K04394","EC:3.4.22.57;EC:3.4.22.64","caspase 4 [Source:HGNC Symbol;Acc:HGNC:1505]",{"v":0.488668,"d":"0.49"},{"v":6.416371,"d":"6.42"},{"v":0.0761595612223794,"d":"0.08"},{"v":-3.71483102289516,"d":"-3.71"},{"v":9.28682335261973e-07,"d":"0.00"},{"v":5.64874992564528e-05,"d":"0.00"},"down","yes"]
[166698,0,"chr6","-",53001279,53061770,"ENST00000350082",14,6116,"MSTRG.13094","ICK","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0005829(cytosol);GO:0005856(cytoskeleton);GO:0042995(cell projection);GO:0005515(protein binding);GO:0007165(signal transduction);GO:0007275(multicellular organism development);GO:0000287(magnesium ion binding);GO:0042073(intraciliary transport);GO:0060271(cilium assembly);GO:0005929(cilium);GO:0030030(cell projection organization);GO:0097546(ciliary base);GO:0036064(ciliary basal body);GO:0010468(regulation of gene expression);GO:0035556(intracellular signal transduction);GO:0097542(ciliary tip);GO:0035721(intraciliary retrograde transport);GO:0035720(intraciliary anterograde transport)","NA","NA","NA","intestinal cell kinase [Source:HGNC Symbol;Acc:HGNC:21219]",{"v":2.162886,"d":"2.16"},{"v":0.184367,"d":"0.18"},{"v":11.7314161428021,"d":"11.73"},{"v":3.55230527184117,"d":"3.55"},{"v":9.30708496362829e-07,"d":"0.00"},{"v":5.64874992564528e-05,"d":"0.00"},"up","yes"]
[194140,0,"chr9","+",129835470,129881828,"ENST00000315480",25,4458,"MSTRG.15035","USP20","GO:0005737(cytoplasm);GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0004843(thiol-dependent ubiquitin-specific protease activity);GO:0016579(protein deubiquitination);GO:0016787(hydrolase activity);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0008233(peptidase activity);GO:0008234(cysteine-type peptidase activity);GO:0006508(proteolysis);GO:0006511(ubiquitin-dependent protein catabolic process);GO:0036459(thiol-dependent ubiquitinyl hydrolase activity);GO:0048471(perinuclear region of cytoplasm);GO:0005813(centrosome);GO:0005815(microtubule organizing center);GO:0005829(cytosol);GO:0006897(endocytosis);GO:0070536(protein K63-linked deubiquitination);GO:0071108(protein K48-linked deubiquitination);GO:0001664(G-protein coupled receptor binding);GO:0008277(regulation of G-protein coupled receptor protein signaling pathway);GO:0004197(cysteine-type endopeptidase activity)","NA","NA","NA","ubiquitin specific peptidase 20 [Source:HGNC Symbol;Acc:HGNC:12619]",{"v":2.704763,"d":"2.70"},{"v":0.229455,"d":"0.23"},{"v":11.7877710226406,"d":"11.79"},{"v":3.55921903639427,"d":"3.56"},{"v":9.79391731642236e-07,"d":"0.00"},{"v":5.9262103325552e-05,"d":"0.00"},"up","yes"]
[88708,"j","chr17","-",78107401,78128771,"MSTRG.7280.3",21,7189,"MSTRG.7280","TMC6","NA","NA","NA","NA","NA",{"v":11.169585,"d":"11.17"},{"v":0.998878,"d":"1.00"},{"v":11.1821313513762,"d":"11.18"},{"v":3.48312329174469,"d":"3.48"},{"v":9.89256412399525e-07,"d":"0.00"},{"v":5.96781632712801e-05,"d":"0.00"},"up","yes"]
[24142,0,"chr10","-",124007668,124092454,"ENST00000346248",8,4810,"MSTRG.2025","CHST15","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016740(transferase activity);GO:0005794(Golgi apparatus);GO:0000139(Golgi membrane);GO:0030206(chondroitin sulfate biosynthetic process);GO:0050656(3'-phosphoadenosine 5'-phosphosulfate binding);GO:0050659(N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase activity);GO:0019319(hexose biosynthetic process)","00532(Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate)","K08106","EC:2.8.2.33","carbohydrate sulfotransferase 15 [Source:HGNC Symbol;Acc:HGNC:18137]",{"v":0.962278,"d":"0.96"},{"v":11.712687,"d":"11.71"},{"v":0.0821568953392163,"d":"0.08"},{"v":-3.60547452568612,"d":"-3.61"},{"v":9.92585777205149e-07,"d":"0.00"},{"v":5.96986530097362e-05,"d":"0.00"},"down","yes"]
[48603,0,"chr12","-",132136594,132144335,"ENST00000397333",15,4718,"ENSG00000185163","DDX51","GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0005634(nucleus);GO:0016020(membrane);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0016787(hydrolase activity);GO:0004386(helicase activity);GO:0042254(ribosome biogenesis);GO:0005730(nucleolus);GO:0006364(rRNA processing);GO:0005737(cytoplasm);GO:0004004(ATP-dependent RNA helicase activity);GO:0010501(RNA secondary structure unwinding)","NA","NA","NA","DEAD-box helicase 51 [Source:HGNC Symbol;Acc:HGNC:20082]",{"v":1.909954,"d":"1.91"},{"v":0.159401,"d":"0.16"},{"v":11.98207037597,"d":"11.98"},{"v":3.58280530711052,"d":"3.58"},{"v":1.00114330173323e-06,"d":"0.00"},{"v":6.00325208678955e-05,"d":"0.00"},"up","yes"]
[126305,0,"chr21","-",25881610,26170667,"ENST00000358918",17,2366,"MSTRG.9967","APP","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0046872(metal ion binding);GO:0003677(DNA binding);GO:0007155(cell adhesion);GO:0005794(Golgi apparatus);GO:0004867(serine-type endopeptidase inhibitor activity);GO:0010951(negative regulation of endopeptidase activity);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0007399(nervous system development);GO:0006915(apoptotic process);GO:0048471(perinuclear region of cytoplasm);GO:0005615(extracellular space);GO:0007219(Notch signaling pathway);GO:0005790(smooth endoplasmic reticulum);GO:0005905(clathrin-coated pit);GO:0008201(heparin binding);GO:0005576(extracellular region);GO:0030414(peptidase inhibitor activity);GO:0010466(negative regulation of peptidase activity);GO:0042802(identical protein binding);GO:0046914(transition metal ion binding);GO:0016504(peptidase activator activity);GO:0070851(growth factor receptor binding);GO:0001967(suckling behavior);GO:0006378(mRNA polyadenylation);GO:0006417(regulation of translation);GO:0006468(protein phosphorylation);GO:0006878(cellular copper ion homeostasis);GO:0006897(endocytosis);GO:0006979(response to oxidative stress);GO:0007176(regulation of epidermal growth factor-activated receptor activity);GO:0007409(axonogenesis);GO:0007617(mating behavior);GO:0007626(locomotory behavior);GO:0008088(axo-dendritic transport);GO:0008203(cholesterol metabolic process);GO:0008344(adult locomotory behavior);GO:0008542(visual learning);GO:0010288(response to lead ion);GO:0010468(regulation of gene expression);GO:0010952(positive regulation of peptidase activity);GO:0010971(positive regulation of G2/M transition of mitotic cell cycle);GO:0016199(axon midline choice point recognition);GO:0016322(neuron remodeling);GO:0016358(dendrite development);GO:0030198(extracellular matrix organization);GO:0030900(forebrain development);GO:0031175(neuron projection development);GO:0035235(ionotropic glutamate receptor signaling pathway);GO:0040014(regulation of multicellular organism growth);GO:0043393(regulation of protein binding);GO:0045665(negative regulation of neuron differentiation);GO:0045931(positive regulation of mitotic cell cycle);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0048669(collateral sprouting in absence of injury);GO:0050803(regulation of synapse structure or activity);GO:0050885(neuromuscular process controlling balance);GO:0051124(synaptic growth at neuromuscular junction);GO:0051247(positive regulation of protein metabolic process);GO:0051402(neuron apoptotic process);GO:0051563(smooth endoplasmic reticulum calcium ion homeostasis);GO:0071320(cellular response to cAMP);GO:0071874(cellular response to norepinephrine stimulus);GO:1990090(cellular response to nerve growth factor stimulus);GO:0005791(rough endoplasmic reticulum);GO:0005911(cell-cell junction);GO:0009986(cell surface);GO:0030134(ER to Golgi transport vesicle);GO:0030424(axon);GO:0030426(growth cone);GO:0031410(cytoplasmic vesicle);GO:0031594(neuromuscular junction);GO:0035253(ciliary rootlet);GO:0043005(neuron projection);GO:0043195(terminal bouton);GO:0044304(main axon);GO:0045177(apical part of cell);GO:0051233(spindle midzone);GO:0097449(astrocyte projection);GO:1990761(growth cone lamellipodium);GO:1990812(growth cone filopodium);GO:0005768(endosome);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0044267(cellular protein metabolic process);GO:0008285(negative regulation of cell proliferation);GO:0043687(post-translational protein modification);GO:0045087(innate immune response);GO:0005887(integral component of plasma membrane);GO:0031904(endosome lumen);GO:0032588(trans-Golgi network membrane);GO:0002576(platelet degranulation);GO:0010628(positive regulation of gene expression);GO:1904646(cellular response to amyloid-beta);GO:0005788(endoplasmic reticulum lumen);GO:0031093(platelet alpha granule lumen);GO:0005796(Golgi lumen);GO:0005102(receptor binding);GO:0043235(receptor complex);GO:0019899(enzyme binding);GO:0014005(microglia development);GO:0032640(tumor necrosis factor production);GO:0043197(dendritic spine);GO:0045202(synapse);GO:0007611(learning or memory);GO:0090647(modulation of age-related behavioral decline);GO:1900273(positive regulation of long-term synaptic potentiation);GO:0046330(positive regulation of JNK cascade);GO:0051425(PTB domain binding);GO:0001934(positive regulation of protein phosphorylation);GO:0002265(astrocyte activation involved in immune response);GO:0009987(cellular process);GO:0010629(negative regulation of gene expression);GO:0048143(astrocyte activation);GO:0048169(regulation of long-term neuronal synaptic plasticity);GO:0050808(synapse organization);GO:0051091(positive regulation of sequence-specific DNA binding transcription factor activity);GO:0098815(modulation of excitatory postsynaptic potential);GO:1990000(amyloid fibril formation);GO:2000310(regulation of NMDA receptor activity);GO:0005641(nuclear envelope lumen);GO:0043198(dendritic shaft);GO:0045121(membrane raft)","04726(Serotonergic synapse);05010(Alzheimer's disease)","K04520","NA","amyloid beta precursor protein [Source:HGNC Symbol;Acc:HGNC:620]",{"v":0.898462,"d":"0.90"},{"v":11.090159,"d":"11.09"},{"v":0.0810143479457779,"d":"0.08"},{"v":-3.62567875243037,"d":"-3.63"},{"v":1.02146165706877E-6,"d":"0.00"},{"v":6.09028307789897e-05,"d":"0.00"},"down","yes"]
[40203,"j","chr12","+",31958570,31993082,"MSTRG.3283.1",5,6886,"MSTRG.3283","KIAA1551","NA","NA","NA","NA","NA",{"v":1.088262,"d":"1.09"},{"v":13.138279,"d":"13.14"},{"v":0.082831396714897,"d":"0.08"},{"v":-3.59367847399169,"d":"-3.59"},{"v":1.02175722711146e-06,"d":"0.00"},{"v":6.09028307789897e-05,"d":"0.00"},"down","yes"]
[103487,0,"chr19","+",48325581,48330553,"ENST00000597279",6,683,"MSTRG.8277","EMP3","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016049(cell growth);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0008219(cell death);GO:0008285(negative regulation of cell proliferation);GO:0032060(bleb assembly)","NA","NA","NA","epithelial membrane protein 3 [Source:HGNC Symbol;Acc:HGNC:3335]",{"v":1.854578,"d":"1.85"},{"v":23.185789,"d":"23.19"},{"v":0.0799877028122701,"d":"0.08"},{"v":-3.64407797046759,"d":"-3.64"},{"v":1.04666814220389e-06,"d":"0.00"},{"v":6.22019924509739e-05,"d":"0.00"},"down","yes"]
[167743,"j","chr6","+",89080713,89084839,"MSTRG.13160.1",3,1704,"MSTRG.13160","PNRC1","NA","NA","NA","NA","NA",{"v":7.717953,"d":"7.72"},{"v":92.189697,"d":"92.19"},{"v":0.0837181729754465,"d":"0.08"},{"v":-3.57831536251011,"d":"-3.58"},{"v":1.05425090731716E-6,"d":"0.00"},{"v":6.246671251427e-05,"d":"0.00"},"down","yes"]
[122529,0,"chr20","-",23633648,23638026,"ENST00000376925",3,873,"MSTRG.9624","CST3","GO:0005615(extracellular space);GO:0010951(negative regulation of endopeptidase activity);GO:0005576(extracellular region);GO:0004869(cysteine-type endopeptidase inhibitor activity);GO:0030414(peptidase inhibitor activity);GO:0010466(negative regulation of peptidase activity);GO:0042802(identical protein binding);GO:0002020(protease binding);GO:0001654(eye development);GO:0001666(response to hypoxia);GO:0001775(cell activation);GO:0006915(apoptotic process);GO:0006979(response to oxidative stress);GO:0007420(brain development);GO:0007431(salivary gland development);GO:0007566(embryo implantation);GO:0008284(positive regulation of cell proliferation);GO:0008584(male gonad development);GO:0009636(response to toxic substance);GO:0009743(response to carbohydrate);GO:0010035(response to inorganic substance);GO:0014070(response to organic cyclic compound);GO:0031667(response to nutrient levels);GO:0032355(response to estradiol);GO:0034599(cellular response to oxidative stress);GO:0042493(response to drug);GO:0042747(circadian sleep/wake cycle, REM sleep);GO:0043067(regulation of programmed cell death);GO:0045740(positive regulation of DNA replication);GO:0048678(response to axon injury);GO:0060009(Sertoli cell development);GO:0060548(negative regulation of cell death);GO:0070301(cellular response to hydrogen peroxide);GO:0005604(basement membrane);GO:0005737(cytoplasm);GO:0005764(lysosome);GO:0005771(multivesicular body);GO:0005783(endoplasmic reticulum);GO:0030424(axon);GO:0031965(nuclear membrane);GO:0031982(vesicle);GO:0042995(cell projection);GO:0043025(neuronal cell body);GO:0043292(contractile fiber);GO:0048471(perinuclear region of cytoplasm);GO:0005515(protein binding);GO:0070062(extracellular exosome);GO:0044267(cellular protein metabolic process);GO:0043687(post-translational protein modification);GO:0043312(neutrophil degranulation);GO:1904813(ficolin-1-rich granule lumen);GO:0005788(endoplasmic reticulum lumen);GO:1904724(tertiary granule lumen);GO:0097435(supramolecular fiber organization);GO:2000117(negative regulation of cysteine-type endopeptidase activity);GO:0001540(amyloid-beta binding);GO:0004866(endopeptidase inhibitor activity);GO:0006952(defense response);GO:0010711(negative regulation of collagen catabolic process);GO:0010716(negative regulation of extracellular matrix disassembly);GO:0034103(regulation of tissue remodeling);GO:0045861(negative regulation of proteolysis);GO:0060311(negative regulation of elastin catabolic process);GO:0060313(negative regulation of blood vessel remodeling)","04970(Salivary secretion)","K13899","NA","cystatin C [Source:HGNC Symbol;Acc:HGNC:2475]",{"v":5.733665,"d":"5.73"},{"v":69.018471,"d":"69.02"},{"v":0.0830743555591082,"d":"0.08"},{"v":-3.58945299337454,"d":"-3.59"},{"v":1.08788252505936e-06,"d":"0.00"},{"v":6.42687522496604e-05,"d":"0.00"},"down","yes"]
[28845,"j","chr11","-",47465979,47553145,"MSTRG.2374.3",14,7788,"MSTRG.2374","CELF1","NA","NA","NA","NA","NA",{"v":0.443344,"d":"0.44"},{"v":5.358776,"d":"5.36"},{"v":0.0827323254414814,"d":"0.08"},{"v":-3.5954050557579,"d":"-3.60"},{"v":1.10707736853928e-06,"d":"0.00"},{"v":6.52097961504199e-05,"d":"0.00"},"down","yes"]
[43573,"j","chr12","+",57694132,57721559,"MSTRG.3487.5",15,2731,"MSTRG.3487","OS9","NA","NA","NA","NA","NA",{"v":0.701554,"d":"0.70"},{"v":8.614888,"d":"8.61"},{"v":0.0814350691500574,"d":"0.08"},{"v":-3.61820598013077,"d":"-3.62"},{"v":1.13537286613805e-06,"d":"0.00"},{"v":6.66797805618956e-05,"d":"0.00"},"down","yes"]
[42405,0,"chr12","-",54230940,54280102,"ENST00000209875",5,11528,"MSTRG.3404","CBX5","GO:0005634(nucleus);GO:0005694(chromosome);GO:0005515(protein binding);GO:0000775(chromosome, centromeric region);GO:0005654(nucleoplasm);GO:0000784(nuclear chromosome, telomeric region);GO:0016032(viral process);GO:0005635(nuclear envelope);GO:0045892(negative regulation of transcription, DNA-templated);GO:0035064(methylated histone binding);GO:0005730(nucleolus);GO:0030674(protein binding, bridging);GO:0007596(blood coagulation);GO:0017053(transcriptional repressor complex);GO:0016605(PML body);GO:0005721(pericentric heterochromatin);GO:0000118(histone deacetylase complex);GO:0070491(repressing transcription factor binding);GO:0031618(nuclear pericentric heterochromatin);GO:0003682(chromatin binding);GO:0042803(protein homodimerization activity);GO:0042826(histone deacetylase binding);GO:0000776(kinetochore);GO:0000792(heterochromatin);GO:0005720(nuclear heterochromatin);GO:0010369(chromocenter);GO:0035097(histone methyltransferase complex)","NA","NA","NA","chromobox 5 [Source:HGNC Symbol;Acc:HGNC:1555]",{"v":4.435045,"d":"4.44"},{"v":0.401173,"d":"0.40"},{"v":11.0551931460991,"d":"11.06"},{"v":3.4666523256937,"d":"3.47"},{"v":1.14051339447674E-6,"d":"0.00"},{"v":6.67852535510603e-05,"d":"0.00"},"up","yes"]
[24141,0,"chr10","-",124007666,124093607,"ENST00000435907",8,4820,"MSTRG.2025","CHST15","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016740(transferase activity);GO:0005794(Golgi apparatus);GO:0000139(Golgi membrane);GO:0030206(chondroitin sulfate biosynthetic process);GO:0050656(3'-phosphoadenosine 5'-phosphosulfate binding);GO:0050659(N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase activity);GO:0019319(hexose biosynthetic process)","00532(Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate)","K08106","EC:2.8.2.33","carbohydrate sulfotransferase 15 [Source:HGNC Symbol;Acc:HGNC:18137]",{"v":1.053005,"d":"1.05"},{"v":12.551848,"d":"12.55"},{"v":0.0838924276329669,"d":"0.08"},{"v":-3.57531559495462,"d":"-3.58"},{"v":1.15794687855446e-06,"d":"0.00"},{"v":6.76078458215656e-05,"d":"0.00"},"down","yes"]
[52903,0,"chr14","+",22547506,22552154,"ENST00000611116",4,976,"MSTRG.4204","TRAC","GO:0016020(membrane);GO:0016021(integral component of membrane)","NA","NA","NA","T-cell receptor alpha constant [Source:HGNC Symbol;Acc:HGNC:12029]",{"v":9.462431,"d":"9.46"},{"v":0.808785,"d":"0.81"},{"v":11.6995629246339,"d":"11.70"},{"v":3.54838272911985,"d":"3.55"},{"v":1.19721961481293e-06,"d":"0.00"},{"v":6.96970299375642e-05,"d":"0.00"},"up","yes"]
[51880,0,"chr13","+",112690329,112887168,"ENST00000375645",30,8795,"ENSG00000068650","ATP11A","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0043231(intracellular membrane-bounded organelle);GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0000287(magnesium ion binding);GO:0016787(hydrolase activity);GO:0005765(lysosomal membrane);GO:0005783(endoplasmic reticulum);GO:0005886(plasma membrane);GO:0006869(lipid transport);GO:0004012(phospholipid-translocating ATPase activity);GO:0015914(phospholipid transport);GO:0005515(protein binding);GO:0005768(endosome);GO:0005769(early endosome);GO:0055037(recycling endosome);GO:0043312(neutrophil degranulation);GO:0035579(specific granule membrane);GO:0070821(tertiary granule membrane);GO:0045332(phospholipid translocation)","NA","NA","NA","ATPase phospholipid transporting 11A [Source:HGNC Symbol;Acc:HGNC:13552]",{"v":0.326887,"d":"0.33"},{"v":3.91494,"d":"3.91"},{"v":0.0834973205208764,"d":"0.08"},{"v":-3.58212628839485,"d":"-3.58"},{"v":1.22620867023013e-06,"d":"0.00"},{"v":7.11771358347533e-05,"d":"0.00"},"down","yes"]
[160634,0,"chr5","-",160251652,160312600,"ENST00000393977",7,3320,"MSTRG.12516","CCNJL","GO:0005634(nucleus);GO:0005515(protein binding)","NA","NA","NA","cyclin J like [Source:HGNC Symbol;Acc:HGNC:25876]",{"v":0.511571,"d":"0.51"},{"v":6.21025,"d":"6.21"},{"v":0.0823752666961877,"d":"0.08"},{"v":-3.60164495881161,"d":"-3.60"},{"v":1.25949758690842e-06,"d":"0.00"},{"v":7.28975298996734e-05,"d":"0.00"},"down","yes"]
[62467,0,"chr15","+",50424382,50499776,"ENST00000307179",20,4243,"MSTRG.5067","USP8","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0016579(protein deubiquitination);GO:0016787(hydrolase activity);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0008233(peptidase activity);GO:0008234(cysteine-type peptidase activity);GO:0006508(proteolysis);GO:0007049(cell cycle);GO:0006511(ubiquitin-dependent protein catabolic process);GO:0036459(thiol-dependent ubiquitinyl hydrolase activity);GO:0014069(postsynaptic density);GO:0043197(dendritic spine);GO:0005768(endosome);GO:0045296(cadherin binding);GO:0005769(early endosome);GO:0004843(thiol-dependent ubiquitin-specific protease activity);GO:0070536(protein K63-linked deubiquitination);GO:0071108(protein K48-linked deubiquitination);GO:0010008(endosome membrane);GO:0017124(SH3 domain binding);GO:0008283(cell proliferation);GO:0030496(midbody);GO:0004197(cysteine-type endopeptidase activity);GO:0007032(endosome organization);GO:0000281(mitotic cytokinesis);GO:0019897(extrinsic component of plasma membrane);GO:0031313(extrinsic component of endosome membrane)","04144(Endocytosis);04137(Mitophagy - animal)","K11839","EC:3.4.19.12","ubiquitin specific peptidase 8 [Source:HGNC Symbol;Acc:HGNC:12631]",{"v":0.182471,"d":"0.18"},{"v":2.313527,"d":"2.31"},{"v":0.0788713509719143,"d":"0.08"},{"v":-3.66435483524534,"d":"-3.66"},{"v":1.27006980590684E-6,"d":"0.00"},{"v":7.32969765443577e-05,"d":"0.00"},"down","yes"]
[179557,"j","chr7","+",142785922,142793374,"MSTRG.14056.8",6,1110,"MSTRG.14056","AC245427.1","NA","NA","NA","NA","NA",{"v":34.87867,"d":"34.88"},{"v":3.194104,"d":"3.19"},{"v":10.9197039294901,"d":"10.92"},{"v":3.44886183528002,"d":"3.45"},{"v":1.29339019413191e-06,"d":"0.00"},{"v":7.44277100761554e-05,"d":"0.00"},"up","yes"]
[17584,0,"chr1","-",244853752,244864494,"ENST00000283179",12,3120,"MSTRG.1497","HNRNPU","GO:0005634(nucleus);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0003723(RNA binding);GO:0006397(mRNA processing);GO:0008380(RNA splicing);GO:0005737(cytoplasm);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0005654(nucleoplasm);GO:0003677(DNA binding);GO:0030529(intracellular ribonucleoprotein complex);GO:0005515(protein binding);GO:0005681(spliceosomal complex);GO:0048511(rhythmic process);GO:0001047(core promoter binding);GO:0031012(extracellular matrix);GO:0000398(mRNA splicing, via spliceosome);GO:0009986(cell surface);GO:0032922(circadian regulation of gene expression);GO:0036464(cytoplasmic ribonucleoprotein granule);GO:0070034(telomerase RNA binding);GO:0005697(telomerase holoenzyme complex);GO:0016070(RNA metabolic process);GO:0006396(RNA processing);GO:0071013(catalytic step 2 spliceosome);GO:0001649(osteoblast differentiation);GO:0070934(CRD-mediated mRNA stabilization);GO:0070937(CRD-mediated mRNA stability complex);GO:0032211(negative regulation of telomere maintenance via telomerase);GO:0034046(poly(G) binding);GO:0035326(enhancer binding);GO:0043021(ribonucleoprotein complex binding);GO:0010628(positive regulation of gene expression);GO:0055013(cardiac muscle cell development);GO:0071549(cellular response to dexamethasone stimulus);GO:2000373(positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity)","03040(Spliceosome)","NA","NA","heterogeneous nuclear ribonucleoprotein U [Source:HGNC Symbol;Acc:HGNC:5048]",{"v":5.086327,"d":"5.09"},{"v":0.454524,"d":"0.45"},{"v":11.1904475891262,"d":"11.19"},{"v":3.48419583644731,"d":"3.48"},{"v":1.32514936414101E-6,"d":"0.00"},{"v":7.60361566182981e-05,"d":"0.00"},"up","yes"]
[189772,0,"chr9","+",34179038,34252520,"ENST00000379186",6,2524,"MSTRG.14732","UBAP1","GO:0006810(transport);GO:0005737(cytoplasm);GO:0015031(protein transport);GO:0005794(Golgi apparatus);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0005768(endosome);GO:0016197(endosomal transport);GO:0019058(viral life cycle);GO:0075733(intracellular transport of virus);GO:0000813(ESCRT I complex);GO:0010008(endosome membrane);GO:0043657(host cell);GO:0043130(ubiquitin binding);GO:0043162(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)","NA","NA","NA","ubiquitin associated protein 1 [Source:HGNC Symbol;Acc:HGNC:12461]",{"v":0.365996,"d":"0.37"},{"v":4.509127,"d":"4.51"},{"v":0.0811678180721013,"d":"0.08"},{"v":-3.62294835781677,"d":"-3.62"},{"v":1.35916780345304e-06,"d":"0.00"},{"v":7.77646495683387e-05,"d":"0.00"},"down","yes"]
[99974,0,"chr19","+",35154747,35169782,"ENST00000592290",9,883,"MSTRG.8070","FXYD5","GO:0016020(membrane);GO:0005216(ion channel activity);GO:0006811(ion transport);GO:0034220(ion transmembrane transport);GO:0006810(transport);GO:0016021(integral component of membrane);GO:0003779(actin binding);GO:0005887(integral component of plasma membrane);GO:0017080(sodium channel regulator activity);GO:2000649(regulation of sodium ion transmembrane transporter activity);GO:0005515(protein binding);GO:0045296(cadherin binding);GO:0030033(microvillus assembly);GO:0046588(negative regulation of calcium-dependent cell-cell adhesion)","NA","NA","NA","FXYD domain containing ion transport regulator 5 [Source:HGNC Symbol;Acc:HGNC:4029]",{"v":1.905253,"d":"1.91"},{"v":22.723011,"d":"22.72"},{"v":0.0838468546267922,"d":"0.08"},{"v":-3.57609952523903,"d":"-3.58"},{"v":1.4086877495906E-6,"d":"0.00"},{"v":8.03676485252145e-05,"d":"0.00"},"down","yes"]
[18851,0,"chr10","+",17229278,17237593,"ENST00000487938",8,2272,"MSTRG.1597","VIM","GO:0005737(cytoplasm);GO:0005198(structural molecule activity);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0005882(intermediate filament);GO:0005925(focal adhesion);GO:0005777(peroxisome);GO:0042802(identical protein binding);GO:0005200(structural constituent of cytoskeleton);GO:0070062(extracellular exosome);GO:0016032(viral process);GO:0031012(extracellular matrix);GO:0008022(protein C-terminus binding);GO:0097110(scaffold protein binding);GO:0006928(movement of cell or subcellular component);GO:0030049(muscle filament sliding);GO:0003725(double-stranded RNA binding);GO:0005212(structural constituent of eye lens);GO:1990254(keratin filament binding);GO:0010628(positive regulation of gene expression);GO:0010977(negative regulation of neuron projection development);GO:0014002(astrocyte development);GO:0045103(intermediate filament-based process);GO:0045109(intermediate filament organization);GO:0060020(Bergmann glial cell differentiation);GO:0060395(SMAD protein signal transduction);GO:0070307(lens fiber cell development);GO:0031252(cell leading edge);GO:0042995(cell projection);GO:0043005(neuron projection)","05206(MicroRNAs in cancer);05169(Epstein-Barr virus infection)","NA","NA","vimentin [Source:HGNC Symbol;Acc:HGNC:12692]",{"v":0.644631,"d":"0.64"},{"v":7.740654,"d":"7.74"},{"v":0.0832786221939386,"d":"0.08"},{"v":-3.58590998965823,"d":"-3.59"},{"v":1.43345885083337E-6,"d":"0.00"},{"v":8.15478812918538e-05,"d":"0.00"},"down","yes"]
[181052,0,"chr8","-",8317736,8381747,"ENST00000622241",5,4639,"ENSG00000275342","PRAG1","GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0004713(protein tyrosine kinase activity);GO:0018108(peptidyl-tyrosine phosphorylation);GO:0004715(non-membrane spanning protein tyrosine kinase activity)","NA","NA","NA","PEAK1 related kinase activating pseudokinase 1 [Source:HGNC Symbol;Acc:HGNC:25438]",{"v":0.162853,"d":"0.16"},{"v":2.01284,"d":"2.01"},{"v":0.0809070765684307,"d":"0.08"},{"v":-3.62759029572656,"d":"-3.63"},{"v":1.50902152698917E-6,"d":"0.00"},{"v":8.560267571284e-05,"d":"0.00"},"down","yes"]
[147079,0,"chr4","-",42408377,42657093,"ENST00000264449",36,8209,"MSTRG.11593","ATP8A1","GO:0016021(integral component of membrane);GO:0005524(ATP binding);GO:0000287(magnesium ion binding);GO:0004012(phospholipid-translocating ATPase activity);GO:0015914(phospholipid transport);GO:0045332(phospholipid translocation);GO:0006810(transport);GO:0016020(membrane);GO:0043231(intracellular membrane-bounded organelle);GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0016787(hydrolase activity);GO:0005794(Golgi apparatus);GO:0005783(endoplasmic reticulum);GO:0005886(plasma membrane);GO:0099132(ATP hydrolysis coupled cation transmembrane transport);GO:0006869(lipid transport);GO:0031410(cytoplasmic vesicle);GO:0000139(Golgi membrane);GO:0005515(protein binding);GO:0070062(extracellular exosome);GO:0034220(ion transmembrane transport);GO:0043312(neutrophil degranulation);GO:0035579(specific granule membrane);GO:0005802(trans-Golgi network);GO:0035577(azurophil granule membrane);GO:0042584(chromaffin granule membrane);GO:0048194(Golgi vesicle budding);GO:0019829(cation-transporting ATPase activity);GO:0007612(learning);GO:0030335(positive regulation of cell migration);GO:0061092(positive regulation of phospholipid translocation)","NA","NA","NA","ATPase phospholipid transporting 8A1 [Source:HGNC Symbol;Acc:HGNC:13531]",{"v":0.114046,"d":"0.11"},{"v":1.383004,"d":"1.38"},{"v":0.08246252360803,"d":"0.08"},{"v":-3.600117576947,"d":"-3.60"},{"v":1.53192942506224E-6,"d":"0.00"},{"v":8.64290012161109e-05,"d":"0.00"},"down","yes"]
[133029,"j","chr3","+",9433302,9476459,"MSTRG.10639.14",22,4926,"MSTRG.10639","SETD5","NA","NA","NA","NA","NA",{"v":2.76831,"d":"2.77"},{"v":0.249153,"d":"0.25"},{"v":11.1108836738871,"d":"11.11"},{"v":3.4739016570002,"d":"3.47"},{"v":1.53224491338658E-6,"d":"0.00"},{"v":8.64290012161109e-05,"d":"0.00"},"up","yes"]
[141897,0,"chr3","+",155080399,155180488,"ENST00000360490",23,2360,"MSTRG.11292","MME","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0046872(metal ion binding);GO:0016787(hydrolase activity);GO:0008270(zinc ion binding);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0008233(peptidase activity);GO:0006508(proteolysis);GO:0045202(synapse);GO:0004222(metalloendopeptidase activity);GO:0008237(metallopeptidase activity);GO:0005925(focal adhesion);GO:0030425(dendrite);GO:0005887(integral component of plasma membrane);GO:0030424(axon);GO:0070062(extracellular exosome);GO:0005903(brush border);GO:0043312(neutrophil degranulation);GO:0030667(secretory granule membrane);GO:0008021(synaptic vesicle);GO:0004175(endopeptidase activity);GO:0042277(peptide binding);GO:0071493(cellular response to UV-B);GO:0001822(kidney development);GO:0071345(cellular response to cytokine stimulus);GO:0019233(sensory perception of pain);GO:0002003(angiotensin maturation);GO:0008238(exopeptidase activity);GO:0006518(peptide metabolic process);GO:0046449(creatinine metabolic process);GO:0050435(amyloid-beta metabolic process);GO:0071492(cellular response to UV-A);GO:0090399(replicative senescence);GO:0044306(neuron projection terminus)","04640(Hematopoietic cell lineage);04614(Renin-angiotensin system);04974(Protein digestion and absorption);05010(Alzheimer's disease)","K01389","EC:3.4.24.11","membrane metalloendopeptidase [Source:HGNC Symbol;Acc:HGNC:7154]",{"v":1.16818,"d":"1.17"},{"v":13.583577,"d":"13.58"},{"v":0.0859994388812314,"d":"0.09"},{"v":-3.53952894305192,"d":"-3.54"},{"v":1.58459325951528E-6,"d":"0.00"},{"v":8.91300231154959e-05,"d":"0.00"},"down","yes"]
[89278,0,"chr17","-",81245000,81295305,"ENST00000374759",16,4300,"MSTRG.7319","SLC38A10","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005794(Golgi apparatus);GO:0006811(ion transport);GO:0006814(sodium ion transport);GO:0015171(amino acid transmembrane transporter activity);GO:0003333(amino acid transmembrane transport);GO:0006865(amino acid transport);GO:0060348(bone development)","NA","NA","NA","solute carrier family 38 member 10 [Source:HGNC Symbol;Acc:HGNC:28237]",{"v":6.618362,"d":"6.62"},{"v":0.61571,"d":"0.62"},{"v":10.749154634487,"d":"10.75"},{"v":3.42615129864723,"d":"3.43"},{"v":1.59414220884516e-06,"d":"0.00"},{"v":8.94152573770228e-05,"d":"0.00"},"up","yes"]
[15578,0,"chr1","+",207752068,207795513,"ENST00000469535",9,7826,"MSTRG.1363","CD46","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0043086(negative regulation of catalytic activity);GO:0031410(cytoplasmic vesicle);GO:0009986(cell surface);GO:0002376(immune system process);GO:0045087(innate immune response);GO:0005925(focal adhesion);GO:0002250(adaptive immune response);GO:0030449(regulation of complement activation);GO:0046718(viral entry into host cell);GO:0070062(extracellular exosome);GO:0010628(positive regulation of gene expression);GO:0042102(positive regulation of T cell proliferation);GO:0007338(single fertilization);GO:0016032(viral process);GO:0005887(integral component of plasma membrane);GO:0002456(T cell mediated immunity);GO:0010629(negative regulation of gene expression);GO:0071636(positive regulation of transforming growth factor beta production);GO:0006958(complement activation, classical pathway);GO:0004872(receptor activity);GO:0045296(cadherin binding);GO:0001618(virus receptor activity);GO:0032733(positive regulation of interleukin-10 production);GO:0008593(regulation of Notch signaling pathway);GO:0032613(interleukin-10 production);GO:0035581(sequestering of extracellular ligand from receptor);GO:0043382(positive regulation of memory T cell differentiation);GO:0045591(positive regulation of regulatory T cell differentiation);GO:0002079(inner acrosomal membrane);GO:0001848(complement binding);GO:0004175(endopeptidase activity);GO:0004857(enzyme inhibitor activity);GO:0006508(proteolysis);GO:0045916(negative regulation of complement activation);GO:0001669(acrosomal vesicle);GO:0005737(cytoplasm);GO:0005794(Golgi apparatus);GO:0016323(basolateral plasma membrane)","04610(Complement and coagulation cascades);05162(Measles)","NA","NA","CD46 molecule [Source:HGNC Symbol;Acc:HGNC:6953]",{"v":0.484407,"d":"0.48"},{"v":5.590631,"d":"5.59"},{"v":0.0866462122075308,"d":"0.09"},{"v":-3.52871950731201,"d":"-3.53"},{"v":1.63315308874037e-06,"d":"0.00"},{"v":9.13467811651758e-05,"d":"0.00"},"down","yes"]
[163474,"j","chr6","+",26440476,26453411,"MSTRG.12749.4",10,2904,"MSTRG.12749","BTN3A3","NA","NA","NA","NA","NA",{"v":0.379149,"d":"0.38"},{"v":4.52286,"d":"4.52"},{"v":0.0838294795770818,"d":"0.08"},{"v":-3.57639851672475,"d":"-3.58"},{"v":1.64952278437296e-06,"d":"0.00"},{"v":9.20046674814503e-05,"d":"0.00"},"down","yes"]
[176098,0,"chr7","-",93131033,93148345,"ENST00000437805",6,5757,"ENSG00000177409","SAMD9L","GO:0005515(protein binding);GO:0005768(endosome);GO:0005769(early endosome);GO:0034058(endosomal vesicle fusion)","NA","NA","NA","sterile alpha motif domain containing 9 like [Source:HGNC Symbol;Acc:HGNC:1349]",{"v":2.66271,"d":"2.66"},{"v":0.245116,"d":"0.25"},{"v":10.8630607549079,"d":"10.86"},{"v":3.4413587462602,"d":"3.44"},{"v":1.66036810000878e-06,"d":"0.00"},{"v":9.2351616214416e-05,"d":"0.00"},"up","yes"]
[28575,"j","chr11","+",46617552,46673105,"MSTRG.2362.7",18,2740,"MSTRG.2362","ATG13","NA","NA","NA","NA","NA",{"v":1.329518,"d":"1.33"},{"v":15.276631,"d":"15.28"},{"v":0.0870295289583155,"d":"0.09"},{"v":-3.52235120198993,"d":"-3.52"},{"v":1.68164456509483e-06,"d":"0.00"},{"v":9.32752185439267e-05,"d":"0.00"},"down","yes"]
[164119,0,"chr6","-",30676391,30687895,"ENST00000615527",3,4597,"MSTRG.12827","PPP1R18","GO:0005737(cytoplasm);GO:0003779(actin binding);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0019902(phosphatase binding)","NA","NA","NA","protein phosphatase 1 regulatory subunit 18 [Source:HGNC Symbol;Acc:HGNC:29413]",{"v":5.758983,"d":"5.76"},{"v":0.543217,"d":"0.54"},{"v":10.601625133234,"d":"10.60"},{"v":3.40621352872749,"d":"3.41"},{"v":1.75383119412593E-6,"d":"0.00"},{"v":9.69272333523165e-05,"d":"0.00"},"up","yes"]
[18205,0,"chr10","-",5765954,5813411,"ENST00000380181",10,1408,"MSTRG.1525","GDI2","GO:0003723(RNA binding);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0015031(protein transport);GO:0007264(small GTPase mediated signal transduction);GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0050790(regulation of catalytic activity);GO:0043547(positive regulation of GTPase activity);GO:0005515(protein binding);GO:0007165(signal transduction);GO:0005096(GTPase activator activity);GO:0005925(focal adhesion);GO:0005092(GDP-dissociation inhibitor activity);GO:0005576(extracellular region);GO:0005093(Rab GDP-dissociation inhibitor activity);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0051056(regulation of small GTPase mediated signal transduction);GO:0061024(membrane organization);GO:0043312(neutrophil degranulation);GO:0034774(secretory granule lumen);GO:0031982(vesicle);GO:0035578(azurophil granule lumen);GO:0031267(small GTPase binding);GO:0016192(vesicle-mediated transport)","NA","NA","NA","GDP dissociation inhibitor 2 [Source:HGNC Symbol;Acc:HGNC:4227]",{"v":3.830926,"d":"3.83"},{"v":43.466011,"d":"43.47"},{"v":0.0881361300902445,"d":"0.09"},{"v":-3.50412263808998,"d":"-3.50"},{"v":1.75719443477257e-06,"d":"0.00"},{"v":9.69272333523165e-05,"d":"0.00"},"down","yes"]
[41212,0,"chr12","-",49185621,49189066,"ENST00000546918",3,984,"MSTRG.3349","TUBA1A","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005525(GTP binding);GO:0000166(nucleotide binding);GO:0003924(GTPase activity);GO:0015630(microtubule cytoskeleton);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0005200(structural constituent of cytoskeleton);GO:0007010(cytoskeleton organization);GO:0005874(microtubule);GO:0007017(microtubule-based process);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0055037(recycling endosome);GO:0000086(G2/M transition of mitotic cell cycle);GO:0010389(regulation of G2/M transition of mitotic cell cycle);GO:0097711(ciliary basal body docking);GO:0036464(cytoplasmic ribonucleoprotein granule);GO:0005198(structural molecule activity);GO:0030705(cytoskeleton-dependent intracellular transport);GO:0051301(cell division);GO:0019904(protein domain specific binding);GO:0005881(cytoplasmic microtubule);GO:0043209(myelin sheath);GO:0045121(membrane raft)","04145(Phagosome);04210(Apoptosis);04530(Tight junction);04540(Gap junction);05130(Pathogenic Escherichia coli infection)","NA","NA","tubulin alpha 1a [Source:HGNC Symbol;Acc:HGNC:20766]",{"v":48.014,"d":"48.01"},{"v":4.583879,"d":"4.58"},{"v":10.4745347772051,"d":"10.47"},{"v":3.38881426343978,"d":"3.39"},{"v":1.77772617200407E-6,"d":"0.00"},{"v":9.77896314120587e-05,"d":"0.00"},"up","yes"]
[199346,0,"chrX","+",110003115,110177788,"ENST00000288381",5,5452,"MSTRG.15402","TMEM164","GO:0016020(membrane);GO:0016021(integral component of membrane)","NA","NA","NA","transmembrane protein 164 [Source:HGNC Symbol;Acc:HGNC:26217]",{"v":5.074584,"d":"5.07"},{"v":0.480049,"d":"0.48"},{"v":10.570970880056,"d":"10.57"},{"v":3.40203598055005,"d":"3.40"},{"v":1.80375288450192e-06,"d":"0.00"},{"v":9.89487296641052e-05,"d":"0.00"},"up","yes"]
[133861,"j","chr3","-",17159004,17742575,"MSTRG.10755.3",23,4666,"MSTRG.10755","TBC1D5","NA","NA","NA","NA","NA",{"v":1.720443,"d":"1.72"},{"v":0.152127,"d":"0.15"},{"v":11.3092547673983,"d":"11.31"},{"v":3.49943195977639,"d":"3.50"},{"v":1.81804930854315e-06,"d":"0.00"},{"v":9.94597495698345e-05,"d":"0.00"},"up","yes"]
[196163,0,"chrX","+",24149724,24216255,"ENST00000379188",9,7513,"ENSG00000005889","ZFX","GO:0005634(nucleus);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0046872(metal ion binding);GO:0003676(nucleic acid binding);GO:0005730(nucleolus);GO:0005654(nucleoplasm);GO:0006351(transcription, DNA-templated);GO:0003713(transcription coactivator activity);GO:0007275(multicellular organism development)","NA","NA","NA","zinc finger protein, X-linked [Source:HGNC Symbol;Acc:HGNC:12869]",{"v":0.081722,"d":"0.08"},{"v":1.002205,"d":"1.00"},{"v":0.0815421994502123,"d":"0.08"},{"v":-3.61630931838953,"d":"-3.62"},{"v":1.83167230020765E-6,"d":"0.00"},{"v":9.99312363129684e-05,"d":"0.00"},"down","yes"]
[196649,"j","chrX","+",45059247,45111707,"MSTRG.15250.8",17,3447,"MSTRG.15250","KDM6A","NA","NA","NA","NA","NA",{"v":6.083236,"d":"6.08"},{"v":0.574567,"d":"0.57"},{"v":10.5875137277289,"d":"10.59"},{"v":3.4042919350388,"d":"3.40"},{"v":1.85167719710723e-06,"d":"0.00"},{"v":1.00747384936886E-4,"d":"0.00"},"up","yes"]
[162472,0,"chr6","-",3153669,3157526,"ENST00000333628",4,1595,"MSTRG.12635","TUBB2A","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005525(GTP binding);GO:0000166(nucleotide binding);GO:0003924(GTPase activity);GO:0015630(microtubule cytoskeleton);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0005200(structural constituent of cytoskeleton);GO:0007010(cytoskeleton organization);GO:0005874(microtubule);GO:0007017(microtubule-based process);GO:0070062(extracellular exosome);GO:1903561(extracellular vesicle)","04145(Phagosome);04540(Gap junction);05130(Pathogenic Escherichia coli infection)","K07375","NA","tubulin beta 2A class IIa [Source:HGNC Symbol;Acc:HGNC:12412]",{"v":15.598443,"d":"15.60"},{"v":1.477106,"d":"1.48"},{"v":10.5601378641749,"d":"10.56"},{"v":3.40055676430562,"d":"3.40"},{"v":1.86607722661713E-6,"d":"0.00"},{"v":0.000101254972992095,"d":"0.00"},"up","yes"]
[8024,0,"chr1","-",92474762,92483954,"ENST00000370332",7,2855,"ENSG00000162676","GFI1","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0030097(hemopoiesis);GO:0051569(regulation of histone H3-K4 methylation);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0071222(cellular response to lipopolysaccharide);GO:0032088(negative regulation of NF-kappaB transcription factor activity);GO:0045892(negative regulation of transcription, DNA-templated);GO:0016363(nuclear matrix);GO:0044212(transcription regulatory region DNA binding);GO:0001078(transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0017053(transcriptional repressor complex);GO:0010956(negative regulation of calcidiol 1-monooxygenase activity);GO:0010977(negative regulation of neuron projection development);GO:0016604(nuclear body);GO:0010957(negative regulation of vitamin D biosynthetic process);GO:0016032(viral process);GO:0034121(regulation of toll-like receptor signaling pathway);GO:0000083(regulation of transcription involved in G1/S transition of mitotic cell cycle);GO:0070105(positive regulation of interleukin-6-mediated signaling pathway)","NA","NA","NA","growth factor independent 1 transcriptional repressor [Source:HGNC Symbol;Acc:HGNC:4237]",{"v":3.020947,"d":"3.02"},{"v":0.274502,"d":"0.27"},{"v":11.0051912190075,"d":"11.01"},{"v":3.46011230766042,"d":"3.46"},{"v":1.87564336880075e-06,"d":"0.00"},{"v":0.000101498229778356,"d":"0.00"},"up","yes"]
[60757,0,"chr15","-",34233259,34336844,"ENST00000397707",24,4194,"MSTRG.4885","SLC12A6","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005215(transporter activity);GO:0055085(transmembrane transport);GO:0006811(ion transport);GO:0005887(integral component of plasma membrane);GO:0015293(symporter activity);GO:0006813(potassium ion transport);GO:0005886(plasma membrane);GO:0071805(potassium ion transmembrane transport);GO:0015377(cation:chloride symporter activity);GO:0015379(potassium:chloride symporter activity);GO:0071477(cellular hypotonic salinity response);GO:1902476(chloride transmembrane transport);GO:0022820(potassium ion symporter activity);GO:0016323(basolateral plasma membrane);GO:0007268(chemical synaptic transmission);GO:0001525(angiogenesis)","NA","NA","NA","solute carrier family 12 member 6 [Source:HGNC Symbol;Acc:HGNC:10914]",{"v":3.671432,"d":"3.67"},{"v":0.343489,"d":"0.34"},{"v":10.6886450512243,"d":"10.69"},{"v":3.41800707593707,"d":"3.42"},{"v":1.9569181079467e-06,"d":"0.00"},{"v":1.0561011021481E-4,"d":"0.00"},"up","yes"]
[130983,0,"chr22","-",37226673,37244432,"ENST00000405484",6,842,"MSTRG.10429","RAC2","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005525(GTP binding);GO:0007264(small GTPase mediated signal transduction);GO:0000166(nucleotide binding);GO:0003924(GTPase activity);GO:0005622(intracellular);GO:0005829(cytosol);GO:0019887(protein kinase regulator activity);GO:0006935(chemotaxis);GO:0007186(G-protein coupled receptor signaling pathway);GO:0008284(positive regulation of cell proliferation);GO:0010592(positive regulation of lamellipodium assembly);GO:0030031(cell projection assembly);GO:0030036(actin cytoskeleton organization);GO:0042129(regulation of T cell proliferation);GO:0043304(regulation of mast cell degranulation);GO:0045453(bone resorption);GO:0045859(regulation of protein kinase activity);GO:0060753(regulation of mast cell chemotaxis);GO:0090023(positive regulation of neutrophil chemotaxis);GO:0005635(nuclear envelope);GO:0005925(focal adhesion);GO:0005886(plasma membrane);GO:0030027(lamellipodium);GO:0070062(extracellular exosome);GO:0051056(regulation of small GTPase mediated signal transduction);GO:0030670(phagocytic vesicle membrane);GO:0007165(signal transduction);GO:0030168(platelet activation);GO:0005884(actin filament);GO:0007015(actin filament organization);GO:1903955(positive regulation of protein targeting to mitochondrion);GO:0010310(regulation of hydrogen peroxide metabolic process);GO:0010810(regulation of cell-substrate adhesion);GO:0060263(regulation of respiratory burst);GO:0071593(lymphocyte aggregation);GO:1902622(regulation of neutrophil migration)","04014(Ras signaling pathway);04015(Rap1 signaling pathway);04010(MAPK signaling pathway);04310(Wnt signaling pathway);04370(VEGF signaling pathway);04071(Sphingolipid signaling pathway);04024(cAMP signaling pathway);04510(Focal adhesion);04520(Adherens junction);04810(Regulation of actin cytoskeleton);04650(Natural killer cell mediated cytotoxicity);04662(B cell receptor signaling pathway);04664(Fc epsilon RI signaling pathway);04666(Fc gamma R-mediated phagocytosis);04670(Leukocyte transendothelial migration);04062(Chemokine signaling pathway);04360(Axon guidance);05200(Pathways in cancer);05231(Choline metabolism in cancer);05210(Colorectal cancer);05212(Pancreatic cancer);05418(Fluid shear stress and atherosclerosis);05416(Viral myocarditis)","NA","NA","ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2) [Source:HGNC Symbol;Acc:HGNC:9802]",{"v":1.367673,"d":"1.37"},{"v":16.039602,"d":"16.04"},{"v":0.0852685122735589,"d":"0.09"},{"v":-3.55184310442539,"d":"-3.55"},{"v":1.96961423612214e-06,"d":"0.00"},{"v":1.05977506859307E-4,"d":"0.00"},"down","yes"]
[132578,0,"chr22","-",50525756,50530032,"ENST00000395678",10,1614,"MSTRG.10610","TYMP","GO:0016740(transferase activity);GO:0016757(transferase activity, transferring glycosyl groups);GO:0008083(growth factor activity);GO:0008152(metabolic process);GO:0007275(multicellular organism development);GO:0030154(cell differentiation);GO:0006935(chemotaxis);GO:0016763(transferase activity, transferring pentosyl groups);GO:0004645(phosphorylase activity);GO:0006206(pyrimidine nucleobase metabolic process);GO:0006213(pyrimidine nucleoside metabolic process);GO:0005829(cytosol);GO:0009032(thymidine phosphorylase activity);GO:0016154(pyrimidine-nucleoside phosphorylase activity);GO:0043097(pyrimidine nucleoside salvage);GO:0001525(angiogenesis);GO:0042803(protein homodimerization activity);GO:0046135(pyrimidine nucleoside catabolic process);GO:0000002(mitochondrial genome maintenance);GO:0031641(regulation of myelination);GO:0051969(regulation of transmission of nerve impulse);GO:1905333(regulation of gastric motility)","00240(Pyrimidine metabolism);00983(Drug metabolism - other enzymes);05219(Bladder cancer)","K00758","EC:2.4.2.4","thymidine phosphorylase [Source:HGNC Symbol;Acc:HGNC:3148]",{"v":8.746911,"d":"8.75"},{"v":0.81644,"d":"0.82"},{"v":10.7134768017246,"d":"10.71"},{"v":3.42135484300659,"d":"3.42"},{"v":1.97922873848652e-06,"d":"0.00"},{"v":1.05977506859307E-4,"d":"0.00"},"up","yes"]
[2840,0,"chr1","-",24899518,24929877,"ENST00000308873",5,3861,"MSTRG.249","RUNX3","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0043231(intracellular membrane-bounded organelle);GO:0005524(ATP binding);GO:0005730(nucleolus);GO:0005829(cytosol);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0005515(protein binding);GO:0045893(positive regulation of transcription, DNA-templated);GO:0005654(nucleoplasm);GO:0000981(RNA polymerase II transcription factor activity, sequence-specific DNA binding);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0045786(negative regulation of cell cycle);GO:0000790(nuclear chromatin);GO:0006366(transcription from RNA polymerase II promoter);GO:0006468(protein phosphorylation);GO:0000977(RNA polymerase II regulatory region sequence-specific DNA binding);GO:0050680(negative regulation of epithelial cell proliferation);GO:0030097(hemopoiesis);GO:0048935(peripheral nervous system neuron development);GO:0001503(ossification);GO:0002062(chondrocyte differentiation);GO:0071559(response to transforming growth factor beta);GO:0045595(regulation of cell differentiation)","04658(Th1 and Th2 cell differentiation)","K09279","NA","runt related transcription factor 3 [Source:HGNC Symbol;Acc:HGNC:10473]",{"v":2.570041,"d":"2.57"},{"v":28.60581,"d":"28.61"},{"v":0.0898433220384251,"d":"0.09"},{"v":-3.4764449160906,"d":"-3.48"},{"v":1.97964793962948e-06,"d":"0.00"},{"v":1.05977506859307E-4,"d":"0.00"},"down","yes"]
[60033,0,"chr15","+",24954948,24978539,"ENST00000554227",12,1763,"MSTRG.4908","SNRPN","GO:0003723(RNA binding);GO:0008380(RNA splicing);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0019013(viral nucleocapsid);GO:0030529(intracellular ribonucleoprotein complex);GO:0005681(spliceosomal complex);GO:0005737(cytoplasm);GO:0005515(protein binding);GO:0000398(mRNA splicing, via spliceosome);GO:0005682(U5 snRNP);GO:0046540(U4/U6 x U5 tri-snRNP complex);GO:0071013(catalytic step 2 spliceosome);GO:0005686(U2 snRNP);GO:0005685(U1 snRNP);GO:0071004(U2-type prespliceosome);GO:0030532(small nuclear ribonucleoprotein complex);GO:0009725(response to hormone);GO:0005687(U4 snRNP)","NA","NA","NA","small nuclear ribonucleoprotein polypeptide N [Source:HGNC Symbol;Acc:HGNC:11164]",{"v":6.004579,"d":"6.00"},{"v":0.553031,"d":"0.55"},{"v":10.8575812205826,"d":"10.86"},{"v":3.44063083985908,"d":"3.44"},{"v":1.98755803917568e-06,"d":"0.00"},{"v":1.06116467717273E-4,"d":"0.00"},"up","yes"]
[142814,0,"chr3","-",177022926,177098493,"ENST00000631253",15,4186,"MSTRG.11351","TBL1XR1","GO:0005634(nucleus);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0016569(covalent chromatin modification);GO:0005515(protein binding);GO:0045893(positive regulation of transcription, DNA-templated);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0003714(transcription corepressor activity);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0005654(nucleoplasm);GO:0000118(histone deacetylase complex);GO:0005876(spindle microtubule);GO:0047485(protein N-terminus binding);GO:0042393(histone binding);GO:0044212(transcription regulatory region DNA binding);GO:0043161(proteasome-mediated ubiquitin-dependent protein catabolic process);GO:0008013(beta-catenin binding);GO:0060070(canonical Wnt signaling pathway);GO:0019216(regulation of lipid metabolic process);GO:0017053(transcriptional repressor complex);GO:0016575(histone deacetylation);GO:0003677(DNA binding);GO:0002021(response to dietary excess);GO:0010468(regulation of gene expression);GO:0016042(lipid catabolic process);GO:0030814(regulation of cAMP metabolic process);GO:0035264(multicellular organism growth);GO:0045892(negative regulation of transcription, DNA-templated);GO:0050872(white fat cell differentiation);GO:0060612(adipose tissue development);GO:0060613(fat pad development);GO:0090207(regulation of triglyceride metabolic process)","04310(Wnt signaling pathway)","K04508","NA","transducin beta like 1 X-linked receptor 1 [Source:HGNC Symbol;Acc:HGNC:29529]",{"v":2.644735,"d":"2.64"},{"v":0.243215,"d":"0.24"},{"v":10.8740620438706,"d":"10.87"},{"v":3.44281905970941,"d":"3.44"},{"v":2.01443038550285e-06,"d":"0.00"},{"v":1.07204382590335E-4,"d":"0.00"},"up","yes"]
[46491,0,"chr12","-",109929804,109996304,"ENST00000361006",19,5444,"MSTRG.3708","GIT2","GO:0046872(metal ion binding);GO:0043547(positive regulation of GTPase activity);GO:0005515(protein binding);GO:0005096(GTPase activator activity);GO:0005654(nucleoplasm);GO:0005925(focal adhesion);GO:0008277(regulation of G-protein coupled receptor protein signaling pathway);GO:0016301(kinase activity);GO:0016310(phosphorylation)","04144(Endocytosis)","K12487","NA","GIT ArfGAP 2 [Source:HGNC Symbol;Acc:HGNC:4273]",{"v":6.053791,"d":"6.05"},{"v":0.584154,"d":"0.58"},{"v":10.3633476788655,"d":"10.36"},{"v":3.37341820790666,"d":"3.37"},{"v":2.01867226832761e-06,"d":"0.00"},{"v":1.07204382590335E-4,"d":"0.00"},"up","yes"]
[184069,0,"chr8","+",58411264,58451501,"ENST00000399598",8,5068,"MSTRG.14367","UBXN2B","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005794(Golgi apparatus);GO:0005829(cytosol);GO:0005783(endoplasmic reticulum);GO:0050790(regulation of catalytic activity);GO:0005515(protein binding);GO:0043161(proteasome-mediated ubiquitin-dependent protein catabolic process);GO:0000045(autophagosome assembly);GO:0007030(Golgi organization);GO:0043130(ubiquitin binding);GO:0061025(membrane fusion);GO:0019888(protein phosphatase regulator activity);GO:0031468(nuclear envelope reassembly)","NA","NA","NA","UBX domain protein 2B [Source:HGNC Symbol;Acc:HGNC:27035]",{"v":0.26137,"d":"0.26"},{"v":3.044846,"d":"3.04"},{"v":0.0858401377278194,"d":"0.09"},{"v":-3.54220379891931,"d":"-3.54"},{"v":2.0297788594258e-06,"d":"0.00"},{"v":1.07508287175104E-4,"d":"0.00"},"down","yes"]
[155908,0,"chr5","+",75511756,75601144,"ENST00000241436",15,5911,"MSTRG.12139","POLK","GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0005654(nucleoplasm);GO:0016740(transferase activity);GO:0003677(DNA binding);GO:0003684(damaged DNA binding);GO:0006281(DNA repair);GO:0006974(cellular response to DNA damage stimulus);GO:0016604(nuclear body);GO:0016779(nucleotidyltransferase activity);GO:0003887(DNA-directed DNA polymerase activity);GO:0006260(DNA replication);GO:0071897(DNA biosynthetic process);GO:0019985(translesion synthesis);GO:0006283(transcription-coupled nucleotide-excision repair);GO:0042276(error-prone translesion synthesis);GO:0006296(nucleotide-excision repair, DNA incision, 5'-to lesion);GO:0033683(nucleotide-excision repair, DNA incision);GO:0006297(nucleotide-excision repair, DNA gap filling)","03460(Fanconi anemia pathway);05200(Pathways in cancer);05202(Transcriptional misregulation in cancers);05210(Colorectal cancer);05212(Pancreatic cancer);05225(Hepatocellular carcinoma);05226(Gastric cancer);05214(Glioma);05216(Thyroid cancer);05220(Chronic myeloid leukemia);05217(Basal cell carcinoma);05218(Melanoma);05213(Endometrial cancer);05224(Breast cancer);05222(Small cell lung cancer);05223(Non-small cell lung cancer)","K03511","EC:2.7.7.7","DNA polymerase kappa [Source:HGNC Symbol;Acc:HGNC:9183]",{"v":1.520324,"d":"1.52"},{"v":0.140606,"d":"0.14"},{"v":10.8126537985577,"d":"10.81"},{"v":3.43464874859288,"d":"3.43"},{"v":2.13528067944277E-6,"d":"0.00"},{"v":1.12797049225167E-4,"d":"0.00"},"up","yes"]
[164389,0,"chr6","+",31463182,31465704,"ENST00000541196",2,2432,"MSTRG.12840","HCP5","NA","NA","NA","NA","HLA complex P5 (non-protein coding) [Source:HGNC Symbol;Acc:HGNC:21659]",{"v":31.265152,"d":"31.27"},{"v":3.070145,"d":"3.07"},{"v":10.1836076146241,"d":"10.18"},{"v":3.34817683171552,"d":"3.35"},{"v":2.17467657683795e-06,"d":"0.00"},{"v":0.000114575044554882,"d":"0.00"},"up","yes"]
[131950,0,"chr22","-",42869775,42959881,"ENST00000407585",10,3080,"MSTRG.10554","PACSIN2","GO:0005737(cytoplasm);GO:0016607(nuclear speck);GO:0016020(membrane);GO:0043231(intracellular membrane-bounded organelle);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0030036(actin cytoskeleton organization);GO:0005856(cytoskeleton);GO:0042995(cell projection);GO:0005515(protein binding);GO:0070836(caveola assembly);GO:0005901(caveola);GO:0030659(cytoplasmic vesicle membrane);GO:0031410(cytoplasmic vesicle);GO:0005925(focal adhesion);GO:0042802(identical protein binding);GO:0008289(lipid binding);GO:0097320(plasma membrane tubulation);GO:0005768(endosome);GO:0045296(cadherin binding);GO:0006897(endocytosis);GO:0070062(extracellular exosome);GO:0061024(membrane organization);GO:0032587(ruffle membrane);GO:0005769(early endosome);GO:0055038(recycling endosome membrane);GO:0019898(extrinsic component of membrane);GO:0030100(regulation of endocytosis);GO:0005215(transporter activity);GO:0070300(phosphatidic acid binding);GO:0072584(caveolin-mediated endocytosis);GO:0036010(protein localization to endosome);GO:0008092(cytoskeletal protein binding);GO:0045806(negative regulation of endocytosis);GO:0048858(cell projection morphogenesis);GO:0005911(cell-cell junction)","NA","NA","NA","protein kinase C and casein kinase substrate in neurons 2 [Source:HGNC Symbol;Acc:HGNC:8571]",{"v":0.385412,"d":"0.39"},{"v":4.458738,"d":"4.46"},{"v":0.0864397055848538,"d":"0.09"},{"v":-3.53216203141343,"d":"-3.53"},{"v":2.1861035881093e-06,"d":"0.00"},{"v":1.14873990650965E-4,"d":"0.00"},"down","yes"]
[12427,0,"chr1","+",159009892,159055155,"ENST00000368131",11,2734,"MSTRG.1105","IFI16","GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005730(nucleolus);GO:0005829(cytosol);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0006915(apoptotic process);GO:0006914(autophagy);GO:0002376(immune system process);GO:0045087(innate immune response);GO:0006954(inflammatory response);GO:0051607(defense response to virus);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:0001047(core promoter binding);GO:0001078(transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0001819(positive regulation of cytokine production);GO:0008283(cell proliferation);GO:0045071(negative regulation of viral genome replication);GO:0045824(negative regulation of innate immune response);GO:0003690(double-stranded DNA binding);GO:0008134(transcription factor binding);GO:0045892(negative regulation of transcription, DNA-templated);GO:0010506(regulation of autophagy);GO:0030097(hemopoiesis);GO:0032481(positive regulation of type I interferon production);GO:0002218(activation of innate immune response);GO:0032731(positive regulation of interleukin-1 beta production);GO:0071479(cellular response to ionizing radiation);GO:0042149(cellular response to glucose starvation);GO:0072332(intrinsic apoptotic signaling pathway by p53 class mediator);GO:0097202(activation of cysteine-type endopeptidase activity);GO:0040029(regulation of gene expression, epigenetic);GO:0042771(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator);GO:0043392(negative regulation of DNA binding);GO:0030224(monocyte differentiation);GO:0005654(nucleoplasm);GO:2000117(negative regulation of cysteine-type endopeptidase activity);GO:0016607(nuclear speck);GO:0030099(myeloid cell differentiation)","04621(NOD-like receptor signaling pathway)","K20914","NA","interferon gamma inducible protein 16 [Source:HGNC Symbol;Acc:HGNC:5395]",{"v":0.245481,"d":"0.25"},{"v":2.960114,"d":"2.96"},{"v":0.0829295763609104,"d":"0.08"},{"v":-3.59196946731352,"d":"-3.59"},{"v":2.33843476284807e-06,"d":"0.00"},{"v":0.000122451259058297,"d":"0.00"},"down","yes"]
[133512,0,"chr3","-",12836050,12841545,"ENST00000435983",4,620,"MSTRG.10672","RPL32","GO:0003723(RNA binding);GO:0016020(membrane);GO:0006412(translation);GO:0030529(intracellular ribonucleoprotein complex);GO:0005622(intracellular);GO:0003735(structural constituent of ribosome);GO:0005840(ribosome);GO:0071549(cellular response to dexamethasone stimulus);GO:0097421(liver regeneration);GO:0022625(cytosolic large ribosomal subunit);GO:0005829(cytosol);GO:0006413(translational initiation);GO:0006364(rRNA processing);GO:0000184(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay);GO:0019083(viral transcription);GO:0006614(SRP-dependent cotranslational protein targeting to membrane)","03010(Ribosome)","NA","NA","ribosomal protein L32 [Source:HGNC Symbol;Acc:HGNC:10336]",{"v":10.186561,"d":"10.19"},{"v":111.591949,"d":"111.59"},{"v":0.0912840136881201,"d":"0.09"},{"v":-3.45349396255827,"d":"-3.45"},{"v":2.34256715546222e-06,"d":"0.00"},{"v":0.000122451259058297,"d":"0.00"},"down","yes"]
[134178,0,"chr3","-",25615473,25664907,"ENST00000424225",27,3525,"MSTRG.10746","TOP2B","GO:0005524(ATP binding);GO:0003677(DNA binding);GO:0006265(DNA topological change);GO:0003918(DNA topoisomerase type II (ATP-hydrolyzing) activity);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0016853(isomerase activity);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0006259(DNA metabolic process);GO:0003916(DNA topoisomerase activity);GO:0000712(resolution of meiotic recombination intermediates);GO:0003682(chromatin binding);GO:0008022(protein C-terminus binding);GO:0019899(enzyme binding);GO:0046982(protein heterodimerization activity);GO:0042826(histone deacetylase binding);GO:0016925(protein sumoylation);GO:0000792(heterochromatin);GO:0005080(protein kinase C binding);GO:0000819(sister chromatid segregation);GO:0044774(mitotic DNA integrity checkpoint);GO:0001764(neuron migration);GO:0007409(axonogenesis);GO:0030900(forebrain development)","01524(Platinum drug resistance)","NA","NA","topoisomerase (DNA) II beta [Source:HGNC Symbol;Acc:HGNC:11990]",{"v":5.874129,"d":"5.87"},{"v":0.572653,"d":"0.57"},{"v":10.2577459648339,"d":"10.26"},{"v":3.35864184312138,"d":"3.36"},{"v":2.39430974556327e-06,"d":"0.00"},{"v":0.000124829182766077,"d":"0.00"},"up","yes"]
[123087,"j","chr20","+",34519419,34540958,"MSTRG.9667.6",4,698,"MSTRG.9667","DYNLRB1","NA","NA","NA","NA","NA",{"v":22.21352,"d":"22.21"},{"v":2.13001,"d":"2.13"},{"v":10.4288336674476,"d":"10.43"},{"v":3.3825059146551,"d":"3.38"},{"v":2.42139829375507E-6,"d":"0.00"},{"v":1.25912711275263E-4,"d":"0.00"},"up","yes"]
[142893,0,"chr3","-",179017223,179072279,"ENST00000311417",6,9406,"ENSG00000172667","ZMAT3","GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0006810(transport);GO:0005634(nucleus);GO:0015031(protein transport);GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0005654(nucleoplasm);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0006974(cellular response to DNA damage stimulus);GO:0006915(apoptotic process);GO:0005730(nucleolus);GO:0040008(regulation of growth);GO:0002039(p53 binding);GO:0072332(intrinsic apoptotic signaling pathway by p53 class mediator);GO:0043065(positive regulation of apoptotic process)","04115(p53 signaling pathway)","K10137","NA","zinc finger matrin-type 3 [Source:HGNC Symbol;Acc:HGNC:29983]",{"v":1.527164,"d":"1.53"},{"v":0.145838,"d":"0.15"},{"v":10.4716466215938,"d":"10.47"},{"v":3.38841641261201,"d":"3.39"},{"v":2.48302333284933e-06,"d":"0.00"},{"v":0.000128781843922949,"d":"0.00"},"up","yes"]
[60168,0,"chr15","-",25333728,25439037,"ENST00000614096",13,8741,"MSTRG.4990","UBE3A","GO:0016567(protein ubiquitination);GO:0004842(ubiquitin-protein transferase activity);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0016740(transferase activity);GO:0016874(ligase activity);GO:0005515(protein binding);GO:0000502(proteasome complex);GO:0048511(rhythmic process);GO:0061630(ubiquitin protein ligase activity);GO:0006511(ubiquitin-dependent protein catabolic process);GO:0016032(viral process);GO:0051865(protein autoubiquitination);GO:0007420(brain development);GO:0070936(protein K48-linked ubiquitination);GO:0042752(regulation of circadian rhythm);GO:0006508(proteolysis);GO:2000058(regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process);GO:0031398(positive regulation of protein ubiquitination);GO:0003713(transcription coactivator activity);GO:0001541(ovarian follicle development);GO:0014068(positive regulation of phosphatidylinositol 3-kinase signaling);GO:0030521(androgen receptor signaling pathway);GO:0035037(sperm entry);GO:0042220(response to cocaine);GO:0042542(response to hydrogen peroxide);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0060736(prostate gland growth);GO:0061002(negative regulation of dendritic spine morphogenesis);GO:1990416(cellular response to brain-derived neurotrophic factor stimulus);GO:0005829(cytosol)","04120(Ubiquitin mediated proteolysis);05203(Viral carcinogenesis);05165(Human papillomavirus infection)","K10587","EC:2.3.2.26","ubiquitin protein ligase E3A [Source:HGNC Symbol;Acc:HGNC:12496]",{"v":0.111033,"d":"0.11"},{"v":1.276919,"d":"1.28"},{"v":0.0869538318405475,"d":"0.09"},{"v":-3.52360658483577,"d":"-3.52"},{"v":2.62456559101589E-6,"d":"0.00"},{"v":0.000135770273889651,"d":"0.00"},"down","yes"]
[53808,0,"chr14","+",24429938,24438408,"ENST00000553935",8,3359,"MSTRG.4292","KHNYN","GO:0003674(molecular_function);GO:0008150(biological_process);GO:0005575(cellular_component);GO:0003723(RNA binding)","NA","NA","NA","KH and NYN domain containing [Source:HGNC Symbol;Acc:HGNC:20166]",{"v":0.393048,"d":"0.39"},{"v":4.411613,"d":"4.41"},{"v":0.0890939436437421,"d":"0.09"},{"v":-3.48852882505454,"d":"-3.49"},{"v":2.64315012779436e-06,"d":"0.00"},{"v":1.36378350779839E-4,"d":"0.00"},"down","yes"]
[150952,0,"chr4","-",139057855,139084496,"ENST00000358635",7,3036,"ENSG00000109381","ELF2","GO:0005634(nucleus);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0043565(sequence-specific DNA binding);GO:0005515(protein binding);GO:0016604(nuclear body);GO:0045893(positive regulation of transcription, DNA-templated);GO:0000981(RNA polymerase II transcription factor activity, sequence-specific DNA binding);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0030154(cell differentiation);GO:0050855(regulation of B cell receptor signaling pathway)","NA","NA","NA","E74 like ETS transcription factor 2 [Source:HGNC Symbol;Acc:HGNC:3317]",{"v":0.274148,"d":"0.27"},{"v":3.163924,"d":"3.16"},{"v":0.0866480990061708,"d":"0.09"},{"v":-3.52868809168131,"d":"-3.53"},{"v":2.67145536598321e-06,"d":"0.00"},{"v":1.37483558628744E-4,"d":"0.00"},"down","yes"]
[94526,"j","chr19","-",2037604,2050915,"MSTRG.7627.8",11,3883,"MSTRG.7627","MKNK2","NA","NA","NA","NA","NA",{"v":4.300094,"d":"4.30"},{"v":45.854584,"d":"45.85"},{"v":0.0937767530504693,"d":"0.09"},{"v":-3.41462586208175,"d":"-3.41"},{"v":2.74222040099176E-6,"d":"0.00"},{"v":0.000140762614311063,"d":"0.00"},"down","yes"]
[183961,0,"chr8","-",56073054,56074510,"ENST00000520627",3,423,"MSTRG.14365","RPS20","GO:0003723(RNA binding);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0006412(translation);GO:0030529(intracellular ribonucleoprotein complex);GO:0005622(intracellular);GO:0003735(structural constituent of ribosome);GO:0005840(ribosome);GO:0015935(small ribosomal subunit);GO:0005515(protein binding);GO:0022627(cytosolic small ribosomal subunit);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0031012(extracellular matrix);GO:0002181(cytoplasmic translation);GO:0006413(translational initiation);GO:0006364(rRNA processing);GO:0000184(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay);GO:0019083(viral transcription);GO:0006614(SRP-dependent cotranslational protein targeting to membrane)","03010(Ribosome)","NA","NA","ribosomal protein S20 [Source:HGNC Symbol;Acc:HGNC:10405]",{"v":20.308168,"d":"20.31"},{"v":1.92838,"d":"1.93"},{"v":10.531206504942,"d":"10.53"},{"v":3.39659882270266,"d":"3.40"},{"v":2.78764378005843e-06,"d":"0.00"},{"v":0.000142727361538992,"d":"0.00"},"up","yes"]
[189193,0,"chr9","-",15485903,15510289,"ENST00000487363",5,660,"MSTRG.14696","PSIP1","GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0000395(mRNA 5'-splice site recognition);GO:0005829(cytosol);GO:0016032(viral process);GO:0006979(response to oxidative stress);GO:0009408(response to heat);GO:0097100(supercoiled DNA binding);GO:0051169(nuclear transport);GO:0075713(establishment of integrated proviral latency);GO:0035327(transcriptionally active chromatin)","NA","NA","NA","PC4 and SFRS1 interacting protein 1 [Source:HGNC Symbol;Acc:HGNC:9527]",{"v":14.626425,"d":"14.63"},{"v":1.405851,"d":"1.41"},{"v":10.4039652850836,"d":"10.40"},{"v":3.37906158544763,"d":"3.38"},{"v":2.84117031389052e-06,"d":"0.00"},{"v":0.0001450958793549,"d":"0.00"},"up","yes"]
[102947,0,"chr19","-",45818913,45863130,"ENST00000599460",22,5449,"MSTRG.8238","SYMPK","GO:0006397(mRNA processing);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0007155(cell adhesion);GO:0005886(plasma membrane);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0030054(cell junction);GO:0005923(bicellular tight junction);GO:0006369(termination of RNA polymerase II transcription);GO:0031124(mRNA 3'-end processing);GO:0000398(mRNA splicing, via spliceosome);GO:0006406(mRNA export from nucleus);GO:0006378(mRNA polyadenylation);GO:0097165(nuclear stress granule);GO:0035307(positive regulation of protein dephosphorylation)","03015(mRNA surveillance pathway);04530(Tight junction)","NA","NA","symplekin [Source:HGNC Symbol;Acc:HGNC:22935]",{"v":2.851183,"d":"2.85"},{"v":0.279736,"d":"0.28"},{"v":10.1924064117597,"d":"10.19"},{"v":3.3494228047273,"d":"3.35"},{"v":2.91086769522164e-06,"d":"0.00"},{"v":0.0001482760360668,"d":"0.00"},"up","yes"]
[123104,0,"chr20","+",34704290,34713439,"ENST00000374810",5,4184,"MSTRG.9681","TP53INP2","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0045893(positive regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0005829(cytosol);GO:0006914(autophagy);GO:0031410(cytoplasmic vesicle);GO:0005515(protein binding);GO:0000045(autophagosome assembly);GO:0005776(autophagosome);GO:0010508(positive regulation of autophagy);GO:0016605(PML body);GO:0043130(ubiquitin binding);GO:0001649(osteoblast differentiation);GO:0001894(tissue homeostasis);GO:0006511(ubiquitin-dependent protein catabolic process);GO:0016236(macroautophagy);GO:1903828(negative regulation of cellular protein localization)","04140(Autophagy - animal)","K21247","NA","tumor protein p53 inducible nuclear protein 2 [Source:HGNC Symbol;Acc:HGNC:16104]",{"v":0.79425,"d":"0.79"},{"v":8.559531,"d":"8.56"},{"v":0.0927912989625249,"d":"0.09"},{"v":-3.42986665955272,"d":"-3.43"},{"v":2.92834656116582E-6,"d":"0.00"},{"v":1.48786829855876E-4,"d":"0.00"},"down","yes"]
[114110,0,"chr2","+",126656184,126696664,"ENST00000409836",3,932,"MSTRG.9077","GYPC","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005886(plasma membrane);GO:0050900(leukocyte migration);GO:0005515(protein binding);GO:0005887(integral component of plasma membrane);GO:0004872(receptor activity);GO:0005102(receptor binding);GO:0042803(protein homodimerization activity);GO:0050839(cell adhesion molecule binding);GO:0007156(homophilic cell adhesion via plasma membrane adhesion molecules);GO:0007157(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules);GO:0005913(cell-cell adherens junction);GO:0030863(cortical cytoskeleton);GO:0008037(cell recognition)","05144(Malaria)","K06576","NA","glycophorin C (Gerbich blood group) [Source:HGNC Symbol;Acc:HGNC:4704]",{"v":195.317062,"d":"195.32"},{"v":20.010279,"d":"20.01"},{"v":9.76083651807154,"d":"9.76"},{"v":3.28700479417729,"d":"3.29"},{"v":2.94047352272644e-06,"d":"0.00"},{"v":0.000149023795182238,"d":"0.00"},"up","yes"]
[194990,0,"chr9","-",137007242,137018219,"ENST00000479446",35,6295,"MSTRG.15119","ABCA2","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005215(transporter activity);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0005765(lysosomal membrane);GO:0006629(lipid metabolic process);GO:0055085(transmembrane transport);GO:0031410(cytoplasmic vesicle);GO:0016887(ATPase activity);GO:0005764(lysosome);GO:0005815(microtubule organizing center);GO:0042626(ATPase activity, coupled to transmembrane movement of substances);GO:0005768(endosome);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0010008(endosome membrane);GO:0043190(ATP-binding cassette (ABC) transporter complex);GO:0042632(cholesterol homeostasis);GO:0042493(response to drug);GO:0032383(regulation of intracellular cholesterol transport);GO:0048545(response to steroid hormone)","02010(ABC transporters);04142(Lysosome)","NA","NA","ATP binding cassette subfamily A member 2 [Source:HGNC Symbol;Acc:HGNC:32]",{"v":4.459366,"d":"4.46"},{"v":0.450356,"d":"0.45"},{"v":9.90186874383821,"d":"9.90"},{"v":3.30770082549996,"d":"3.31"},{"v":3.10786590380824e-06,"d":"0.00"},{"v":1.57108522448716E-4,"d":"0.00"},"up","yes"]
[195011,0,"chr9","-",137030174,137033010,"ENST00000314412",2,2584,"MSTRG.15121","FUT7","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005794(Golgi apparatus);GO:0016740(transferase activity);GO:0016757(transferase activity, transferring glycosyl groups);GO:0006486(protein glycosylation);GO:0032580(Golgi cisterna membrane);GO:0036065(fucosylation);GO:0008417(fucosyltransferase activity);GO:0000139(Golgi membrane);GO:0042355(L-fucose catabolic process);GO:0006672(ceramide metabolic process);GO:0046920(alpha-(1->3)-fucosyltransferase activity);GO:0002361(CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation);GO:0002522(leukocyte migration involved in immune response)","00601(Glycosphingolipid biosynthesis - lacto and neolacto series)","K07635","EC:2.4.1.-","fucosyltransferase 7 [Source:HGNC Symbol;Acc:HGNC:4018]",{"v":0.978309,"d":"0.98"},{"v":10.492437,"d":"10.49"},{"v":0.0932394447543502,"d":"0.09"},{"v":-3.42291577660493,"d":"-3.42"},{"v":3.2148273254989e-06,"d":"0.00"},{"v":1.61847213687838E-4,"d":"0.00"},"down","yes"]
[10456,0,"chr1","-",149844498,149849024,"ENST00000564237",1,4527,"ENSG00000261716","AC239868.2","NA","NA","NA","NA","NA",{"v":0.210383,"d":"0.21"},{"v":2.349603,"d":"2.35"},{"v":0.0895398073632013,"d":"0.09"},{"v":-3.48132697535785,"d":"-3.48"},{"v":3.2212624806734e-06,"d":"0.00"},{"v":1.61847213687838E-4,"d":"0.00"},"down","yes"]
[160474,"j","chr5","+",157266096,157395596,"MSTRG.12505.3",31,6870,"MSTRG.12505","CYFIP2","NA","NA","NA","NA","NA",{"v":0.667803,"d":"0.67"},{"v":7.079425,"d":"7.08"},{"v":0.0943301186183906,"d":"0.09"},{"v":-3.40613770791178,"d":"-3.41"},{"v":3.22592102602962E-6,"d":"0.00"},{"v":1.61847213687838E-4,"d":"0.00"},"down","yes"]
[98019,0,"chr19","-",16517896,16542415,"ENST00000198939",17,4084,"MSTRG.7936","CHERP","GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0006396(RNA processing);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005783(endoplasmic reticulum);GO:0005515(protein binding);GO:0048471(perinuclear region of cytoplasm);GO:0005654(nucleoplasm);GO:0044325(ion channel binding);GO:0007399(nervous system development);GO:0033017(sarcoplasmic reticulum membrane);GO:0000398(mRNA splicing, via spliceosome);GO:0051209(release of sequestered calcium ion into cytosol);GO:0008285(negative regulation of cell proliferation);GO:0051533(positive regulation of NFAT protein import into nucleus);GO:0006874(cellular calcium ion homeostasis)","03040(Spliceosome)","NA","NA","calcium homeostasis endoplasmic reticulum protein [Source:HGNC Symbol;Acc:HGNC:16930]",{"v":0.198356,"d":"0.20"},{"v":2.262839,"d":"2.26"},{"v":0.0876580260460422,"d":"0.09"},{"v":-3.51196999831406,"d":"-3.51"},{"v":3.31758240511946e-06,"d":"0.00"},{"v":0.000165661097350317,"d":"0.00"},"down","yes"]
[198735,0,"chrX","+",96685017,97469765,"ENST00000373054",28,3376,"ENSG00000147202","DIAPH2","GO:0005737(cytoplasm);GO:0043231(intracellular membrane-bounded organelle);GO:0005783(endoplasmic reticulum);GO:0005730(nucleolus);GO:0003779(actin binding);GO:0007015(actin filament organization);GO:0005829(cytosol);GO:0030036(actin cytoskeleton organization);GO:0007275(multicellular organism development);GO:0030154(cell differentiation);GO:0016043(cellular component organization);GO:0017048(Rho GTPase binding);GO:0005768(endosome);GO:0005769(early endosome);GO:0007292(female gamete generation);GO:0048477(oogenesis);GO:0005102(receptor binding);GO:0000910(cytokinesis)","04810(Regulation of actin cytoskeleton)","NA","NA","diaphanous related formin 2 [Source:HGNC Symbol;Acc:HGNC:2877]",{"v":0.199094,"d":"0.20"},{"v":2.300533,"d":"2.30"},{"v":0.0865425533995817,"d":"0.09"},{"v":-3.53044650231086,"d":"-3.53"},{"v":3.31853159756244e-06,"d":"0.00"},{"v":0.000165661097350317,"d":"0.00"},"down","yes"]
[173233,0,"chr7","-",36854462,36985060,"ENST00000396040",7,1982,"MSTRG.13575","ELMO1","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005886(plasma membrane);GO:0043547(positive regulation of GTPase activity);GO:0030036(actin cytoskeleton organization);GO:0005515(protein binding);GO:0006915(apoptotic process);GO:0016477(cell migration);GO:0038096(Fc-gamma receptor signaling pathway involved in phagocytosis);GO:0006909(phagocytosis);GO:0005829(cytosol);GO:0017124(SH3 domain binding);GO:0048010(vascular endothelial growth factor receptor signaling pathway);GO:0050690(regulation of defense response to virus by virus);GO:0048870(cell motility);GO:0006911(phagocytosis, engulfment);GO:0016601(Rac protein signal transduction);GO:0005085(guanyl-nucleotide exchange factor activity);GO:0032045(guanyl-nucleotide exchange factor complex);GO:0030029(actin filament-based process)","04062(Chemokine signaling pathway);05131(Shigellosis);05100(Bacterial invasion of epithelial cells)","K12366","NA","engulfment and cell motility 1 [Source:HGNC Symbol;Acc:HGNC:16286]",{"v":0.487924,"d":"0.49"},{"v":5.465374,"d":"5.47"},{"v":0.0892755006336255,"d":"0.09"},{"v":-3.48559187068477,"d":"-3.49"},{"v":3.34723710901336E-6,"d":"0.00"},{"v":1.66677383024386E-4,"d":"0.00"},"down","yes"]
[51327,0,"chr13","+",97222355,97394120,"ENST00000345429",9,4669,"MSTRG.4044","MBNL2","GO:0003723(RNA binding);GO:0006397(mRNA processing);GO:0008380(RNA splicing);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0005654(nucleoplasm);GO:0043484(regulation of RNA splicing);GO:0000381(regulation of alternative mRNA splicing, via spliceosome)","NA","NA","NA","muscleblind like splicing regulator 2 [Source:HGNC Symbol;Acc:HGNC:16746]",{"v":1.618478,"d":"1.62"},{"v":0.155336,"d":"0.16"},{"v":10.4192073955812,"d":"10.42"},{"v":3.38117362874595,"d":"3.38"},{"v":3.40593955174292e-06,"d":"0.00"},{"v":1.68759809028221E-4,"d":"0.00"},"up","yes"]
[73654,0,"chr16","+",57668187,57689378,"ENST00000333493",12,2728,"MSTRG.5962","ADGRG3","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0004930(G-protein coupled receptor activity);GO:0007186(G-protein coupled receptor signaling pathway);GO:0005886(plasma membrane);GO:0004871(signal transducer activity);GO:0007165(signal transduction);GO:0004888(transmembrane signaling receptor activity);GO:0007166(cell surface receptor signaling pathway);GO:0043312(neutrophil degranulation);GO:0035579(specific granule membrane);GO:0030334(regulation of cell migration);GO:1901223(negative regulation of NIK/NF-kappaB signaling);GO:0030183(B cell differentiation);GO:0032792(negative regulation of CREB transcription factor activity)","NA","NA","NA","adhesion G protein-coupled receptor G3 [Source:HGNC Symbol;Acc:HGNC:13728]",{"v":3.354535,"d":"3.35"},{"v":35.024361,"d":"35.02"},{"v":0.095777193479704,"d":"0.10"},{"v":-3.38417402828971,"d":"-3.38"},{"v":3.40595968741853e-06,"d":"0.00"},{"v":1.68759809028221E-4,"d":"0.00"},"down","yes"]
[126722,"j","chr21","+",33543049,33577482,"MSTRG.10037.2",12,8330,"MSTRG.10037","SON","NA","NA","NA","NA","NA",{"v":1.054947,"d":"1.05"},{"v":11.001754,"d":"11.00"},{"v":0.0958889827931074,"d":"0.10"},{"v":-3.38249112409143,"d":"-3.38"},{"v":3.43414462264505e-06,"d":"0.00"},{"v":0.000169735148081624,"d":"0.00"},"down","yes"]
[55149,0,"chr14","-",54474485,54489196,"ENST00000358056",7,4301,"ENSG00000197045","GMFB","GO:0071933(Arp2/3 complex binding);GO:0034316(negative regulation of Arp2/3 complex-mediated actin nucleation);GO:0003779(actin binding);GO:0005622(intracellular);GO:0008083(growth factor activity);GO:0043085(positive regulation of catalytic activity);GO:0006469(negative regulation of protein kinase activity);GO:0006468(protein phosphorylation);GO:0007399(nervous system development);GO:0004871(signal transducer activity);GO:0007165(signal transduction);GO:0004860(protein kinase inhibitor activity);GO:0008047(enzyme activator activity);GO:0007612(learning);GO:0007626(locomotory behavior)","NA","NA","NA","glia maturation factor beta [Source:HGNC Symbol;Acc:HGNC:4373]",{"v":2.135798,"d":"2.14"},{"v":0.207233,"d":"0.21"},{"v":10.3062639637509,"d":"10.31"},{"v":3.36544954323009,"d":"3.37"},{"v":3.49938543941506e-06,"d":"0.00"},{"v":1.72532662849975E-4,"d":"0.00"},"up","yes"]
[19331,0,"chr10","+",28533419,28620543,"ENST00000354911",14,3042,"MSTRG.1633","WAC","GO:0005634(nucleus);GO:0016607(nuclear speck);GO:0005654(nucleoplasm);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0016569(covalent chromatin modification);GO:0005515(protein binding);GO:0006974(cellular response to DNA damage stimulus);GO:0045893(positive regulation of transcription, DNA-templated);GO:0016567(protein ubiquitination);GO:0003682(chromatin binding);GO:0016239(positive regulation of macroautophagy);GO:0032435(negative regulation of proteasomal ubiquitin-dependent protein catabolic process);GO:0010390(histone monoubiquitination);GO:0000993(RNA polymerase II core binding);GO:0044783(G1 DNA damage checkpoint);GO:0071894(histone H2B conserved C-terminal lysine ubiquitination);GO:0005681(spliceosomal complex)","NA","NA","NA","WW domain containing adaptor with coiled-coil [Source:HGNC Symbol;Acc:HGNC:17327]",{"v":3.147666,"d":"3.15"},{"v":32.697716,"d":"32.70"},{"v":0.0962656229566616,"d":"0.10"},{"v":-3.37683549497012,"d":"-3.38"},{"v":3.55502999569896e-06,"d":"0.00"},{"v":0.000174589949660781,"d":"0.00"},"down","yes"]
[184080,0,"chr8","+",58553169,58582860,"ENST00000260130",9,2167,"MSTRG.14373","SDCBP","GO:0005737(cytoplasm);GO:0005634(nucleus);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0043231(intracellular membrane-bounded organelle);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0035556(intracellular signal transduction);GO:0031965(nuclear membrane);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005886(plasma membrane);GO:0030036(actin cytoskeleton organization);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0042470(melanosome);GO:0005615(extracellular space);GO:0030054(cell junction);GO:0045121(membrane raft);GO:0007268(chemical synaptic transmission);GO:0005925(focal adhesion);GO:0042802(identical protein binding);GO:0008289(lipid binding);GO:0045296(cadherin binding);GO:0006930(substrate-dependent cell migration, cell extension);GO:0070062(extracellular exosome);GO:0072562(blood microparticle);GO:0030335(positive regulation of cell migration);GO:0005912(adherens junction);GO:0005546(phosphatidylinositol-4,5-bisphosphate binding);GO:0043312(neutrophil degranulation);GO:0007346(regulation of mitotic cell cycle);GO:0008284(positive regulation of cell proliferation);GO:0032435(negative regulation of proteasomal ubiquitin-dependent protein catabolic process);GO:0006612(protein targeting to membrane);GO:0047485(protein N-terminus binding);GO:0030511(positive regulation of transforming growth factor beta receptor signaling pathway);GO:0046982(protein heterodimerization activity);GO:0048013(ephrin receptor signaling pathway);GO:0005109(frizzled binding);GO:0005137(interleukin-5 receptor binding);GO:0008093(cytoskeletal adaptor activity);GO:0045545(syndecan binding);GO:0002091(negative regulation of receptor internalization);GO:0010718(positive regulation of epithelial to mesenchymal transition);GO:0010862(positive regulation of pathway-restricted SMAD protein phosphorylation);GO:0030307(positive regulation of cell growth);GO:0042327(positive regulation of phosphorylation);GO:0046330(positive regulation of JNK cascade);GO:1903543(positive regulation of exosomal secretion);GO:1903553(positive regulation of extracellular exosome assembly);GO:0005895(interleukin-5 receptor complex);GO:0035578(azurophil granule lumen);GO:1903561(extracellular vesicle);GO:0008022(protein C-terminus binding);GO:0019838(growth factor binding);GO:0042043(neurexin family protein binding);GO:0042803(protein homodimerization activity);GO:0046875(ephrin receptor binding);GO:0050839(cell adhesion molecule binding);GO:0007265(Ras protein signal transduction);GO:0005622(intracellular)","NA","NA","NA","syndecan binding protein [Source:HGNC Symbol;Acc:HGNC:10662]",{"v":5.215146,"d":"5.22"},{"v":53.972595,"d":"53.97"},{"v":0.0966258153790827,"d":"0.10"},{"v":-3.37144750647183,"d":"-3.37"},{"v":3.55859923437189e-06,"d":"0.00"},{"v":0.000174589949660781,"d":"0.00"},"down","yes"]
[107154,"j","chr2","-",8728409,8837613,"MSTRG.8497.3",29,7740,"MSTRG.8497","KIDINS220","NA","NA","NA","NA","NA",{"v":0.92742,"d":"0.93"},{"v":9.651882,"d":"9.65"},{"v":0.0960869600353589,"d":"0.10"},{"v":-3.37951553368516,"d":"-3.38"},{"v":3.57449476013409e-06,"d":"0.00"},{"v":1.74939978848916E-4,"d":"0.00"},"down","yes"]
[195289,"o","chrMT","-",956,12061,"MSTRG.15133.1",4,578,"MSTRG.15133","MT-TN","NA","NA","NA","NA","NA",{"v":108.601791,"d":"108.60"},{"v":11.425499,"d":"11.43"},{"v":9.50521206994986,"d":"9.51"},{"v":3.24871881507498,"d":"3.25"},{"v":3.84921122663769e-06,"d":"0.00"},{"v":0.000187924327074575,"d":"0.00"},"up","yes"]
[166112,0,"chr6","-",43037617,43053699,"ENST00000265348",26,5254,"ENSG00000044090","CUL7","GO:0005737(cytoplasm);GO:0016567(protein ubiquitination);GO:0005794(Golgi apparatus);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0006508(proteolysis);GO:0006511(ubiquitin-dependent protein catabolic process);GO:0048471(perinuclear region of cytoplasm);GO:0031625(ubiquitin protein ligase binding);GO:0000226(microtubule cytoskeleton organization);GO:0005813(centrosome);GO:0005815(microtubule organizing center);GO:0001890(placenta development);GO:0005829(cytosol);GO:0043687(post-translational protein modification);GO:0016032(viral process);GO:0005680(anaphase-promoting complex);GO:0050775(positive regulation of dendrite morphogenesis);GO:0000281(mitotic cytokinesis);GO:0036498(IRE1-mediated unfolded protein response);GO:0007030(Golgi organization);GO:0007088(regulation of mitotic nuclear division);GO:0001570(vasculogenesis);GO:1990393(3M complex);GO:0001837(epithelial to mesenchymal transition);GO:0031467(Cul7-RING ubiquitin ligase complex)","04120(Ubiquitin mediated proteolysis)","K10613","NA","cullin 7 [Source:HGNC Symbol;Acc:HGNC:21024]",{"v":1.412079,"d":"1.41"},{"v":0.137438,"d":"0.14"},{"v":10.2742982290196,"d":"10.27"},{"v":3.36096795097543,"d":"3.36"},{"v":3.9343586558632e-06,"d":"0.00"},{"v":0.000191521809408846,"d":"0.00"},"up","yes"]
[123580,0,"chr20","-",37517417,37527931,"ENST00000373537",2,2073,"MSTRG.9730","BLCAP","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005515(protein binding);GO:0007049(cell cycle);GO:0006915(apoptotic process);GO:0030262(apoptotic nuclear changes)","NA","NA","NA","bladder cancer associated protein [Source:HGNC Symbol;Acc:HGNC:1055]",{"v":13.275043,"d":"13.28"},{"v":1.384578,"d":"1.38"},{"v":9.58778992588356,"d":"9.59"},{"v":3.26119829903646,"d":"3.26"},{"v":3.94208051217126e-06,"d":"0.00"},{"v":0.000191521809408846,"d":"0.00"},"up","yes"]
[110492,0,"chr2","+",68774801,68826833,"ENST00000409030",10,2936,"MSTRG.8782","ARHGAP25","GO:0007165(signal transduction);GO:0043547(positive regulation of GTPase activity);GO:0005096(GTPase activator activity);GO:0005829(cytosol);GO:0051056(regulation of small GTPase mediated signal transduction)","NA","NA","NA","Rho GTPase activating protein 25 [Source:HGNC Symbol;Acc:HGNC:28951]",{"v":0.934437,"d":"0.93"},{"v":9.746333,"d":"9.75"},{"v":0.095875751423638,"d":"0.10"},{"v":-3.38269021003104,"d":"-3.38"},{"v":3.97044466247165e-06,"d":"0.00"},{"v":1.92071124100645E-4,"d":"0.00"},"down","yes"]
[161504,0,"chr5","-",177301198,177303733,"ENST00000478234",7,1820,"MSTRG.12573","RAB24","GO:0006810(transport);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0015031(protein transport);GO:0005525(GTP binding);GO:0000166(nucleotide binding);GO:0003924(GTPase activity);GO:0005829(cytosol);GO:0006914(autophagy);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0043312(neutrophil degranulation);GO:0030667(secretory granule membrane);GO:0005776(autophagosome);GO:0005739(mitochondrion)","NA","NA","NA","RAB24, member RAS oncogene family [Source:HGNC Symbol;Acc:HGNC:9765]",{"v":1.295294,"d":"1.30"},{"v":13.526764,"d":"13.53"},{"v":0.0957578619690563,"d":"0.10"},{"v":-3.38446524886627,"d":"-3.38"},{"v":3.97665913581785e-06,"d":"0.00"},{"v":1.92071124100645E-4,"d":"0.00"},"down","yes"]
[165902,"j","chr6","-",41267552,41286727,"MSTRG.13025.3",5,1255,"MSTRG.13025","TREM1","NA","NA","NA","NA","NA",{"v":1.021426,"d":"1.02"},{"v":10.954192,"d":"10.95"},{"v":0.0932452160780092,"d":"0.09"},{"v":-3.42282647960873,"d":"-3.42"},{"v":3.98224385905785e-06,"d":"0.00"},{"v":1.92071124100645E-4,"d":"0.00"},"down","yes"]
[96546,0,"chr19","+",10718079,10831047,"ENST00000585892",21,2774,"MSTRG.7808","DNM2","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005794(Golgi apparatus);GO:0005525(GTP binding);GO:0000166(nucleotide binding);GO:0005829(cytosol);GO:0016787(hydrolase activity);GO:0006355(regulation of transcription, DNA-templated);GO:0003924(GTPase activity);GO:0006897(endocytosis);GO:0005886(plasma membrane);GO:0005856(cytoskeleton);GO:0042995(cell projection);GO:0005515(protein binding);GO:0007165(signal transduction);GO:0030054(cell junction);GO:0045202(synapse);GO:0045211(postsynaptic membrane);GO:0005874(microtubule);GO:0031410(cytoplasmic vesicle);GO:0005905(clathrin-coated pit);GO:0045893(positive regulation of transcription, DNA-templated);GO:0005925(focal adhesion);GO:0008017(microtubule binding);GO:0030496(midbody);GO:0048812(neuron projection morphogenesis);GO:0030426(growth cone);GO:0070062(extracellular exosome);GO:0001891(phagocytic cup);GO:0030670(phagocytic vesicle membrane);GO:0061024(membrane organization);GO:0043065(positive regulation of apoptotic process);GO:0014069(postsynaptic density);GO:0017124(SH3 domain binding);GO:0019886(antigen processing and presentation of exogenous peptide antigen via MHC class II);GO:0019899(enzyme binding);GO:0006909(phagocytosis);GO:0000139(Golgi membrane);GO:0050999(regulation of nitric-oxide synthase activity);GO:1903526(negative regulation of membrane tubulation);GO:0030666(endocytic vesicle membrane);GO:0048489(synaptic vesicle transport);GO:0000086(G2/M transition of mitotic cell cycle);GO:0003374(dynamin family protein polymerization involved in mitochondrial fission);GO:0006898(receptor-mediated endocytosis);GO:0061025(membrane fusion);GO:0031966(mitochondrial membrane);GO:0030516(regulation of axon extension);GO:0033572(transferrin transport);GO:0000266(mitochondrial fission);GO:0031623(receptor internalization);GO:0019901(protein kinase binding);GO:0031749(D2 dopamine receptor binding);GO:0032403(protein complex binding);GO:0036312(phosphatidylinositol 3-kinase regulatory subunit binding);GO:0050699(WW domain binding);GO:0050998(nitric-oxide synthase binding);GO:0002031(G-protein coupled receptor internalization);GO:0003281(ventricular septum development);GO:0006893(Golgi to plasma membrane transport);GO:0007283(spermatogenesis);GO:0009416(response to light stimulus);GO:0010592(positive regulation of lamellipodium assembly);GO:0030512(negative regulation of transforming growth factor beta receptor signaling pathway);GO:0035020(regulation of Rac protein signal transduction);GO:0035904(aorta development);GO:0042220(response to cocaine);GO:0044351(macropinocytosis);GO:0045429(positive regulation of nitric oxide biosynthetic process);GO:0045807(positive regulation of endocytosis);GO:0050766(positive regulation of phagocytosis);GO:0060976(coronary vasculature development);GO:0071245(cellular response to carbon monoxide);GO:0071481(cellular response to X-ray);GO:0071732(cellular response to nitric oxide);GO:1900026(positive regulation of substrate adhesion-dependent cell spreading);GO:1902856(negative regulation of non-motile cilium assembly);GO:1903351(cellular response to dopamine);GO:1903358(regulation of Golgi organization);GO:1903408(positive regulation of sodium:potassium-exchanging ATPase activity);GO:0001917(photoreceptor inner segment);GO:0005634(nucleus);GO:0005768(endosome);GO:0005802(trans-Golgi network);GO:0005813(centrosome);GO:0030027(lamellipodium);GO:0032587(ruffle membrane);GO:0043234(protein complex);GO:0045334(clathrin-coated endocytic vesicle);GO:0048471(perinuclear region of cytoplasm)","04072(Phospholipase D signaling pathway);04144(Endocytosis);04666(Fc gamma R-mediated phagocytosis);04961(Endocrine and other factor-regulated calcium reabsorption);04721(Synaptic vesicle cycle);05100(Bacterial invasion of epithelial cells)","K01528","EC:3.6.5.5","dynamin 2 [Source:HGNC Symbol;Acc:HGNC:2974]",{"v":0.997839,"d":"1.00"},{"v":10.387779,"d":"10.39"},{"v":0.0960589361787539,"d":"0.10"},{"v":-3.37993635848583,"d":"-3.38"},{"v":4.00666710275687e-06,"d":"0.00"},{"v":0.000192783442669516,"d":"0.00"},"down","yes"]
[183655,0,"chr8","-",47773735,47960178,"ENST00000338368",85,12784,"ENSG00000253729","PRKDC","GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0005634(nucleus);GO:0003723(RNA binding);GO:0016020(membrane);GO:0000166(nucleotide binding);GO:0004674(protein serine/threonine kinase activity);GO:0005524(ATP binding);GO:0005654(nucleoplasm);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0006303(double-strand break repair via nonhomologous end joining);GO:0006281(DNA repair);GO:0006310(DNA recombination);GO:0006974(cellular response to DNA damage stimulus);GO:0048511(rhythmic process);GO:0005730(nucleolus);GO:0016567(protein ubiquitination);GO:0005829(cytosol);GO:0000784(nuclear chromosome, telomeric region);GO:0031012(extracellular matrix);GO:0005667(transcription factor complex);GO:0001933(negative regulation of protein phosphorylation);GO:0043234(protein complex);GO:0019904(protein domain specific binding);GO:0006464(cellular protein modification process);GO:0004672(protein kinase activity);GO:0032481(positive regulation of type I interferon production);GO:0042752(regulation of circadian rhythm);GO:0018105(peptidyl-serine phosphorylation);GO:0032869(cellular response to insulin stimulus);GO:0008134(transcription factor binding);GO:0032993(protein-DNA complex);GO:0043066(negative regulation of apoptotic process);GO:0008283(cell proliferation);GO:0006468(protein phosphorylation);GO:0003690(double-stranded DNA binding);GO:0048660(regulation of smooth muscle cell proliferation);GO:0070419(nonhomologous end joining complex);GO:0006302(double-strand break repair);GO:0005958(DNA-dependent protein kinase-DNA ligase 4 complex);GO:0004677(DNA-dependent protein kinase activity);GO:0019899(enzyme binding);GO:0000723(telomere maintenance);GO:0001756(somitogenesis);GO:0002326(B cell lineage commitment);GO:0002328(pro-B cell differentiation);GO:0002360(T cell lineage commitment);GO:0002377(immunoglobulin production);GO:0002638(negative regulation of immunoglobulin production);GO:0002684(positive regulation of immune system process);GO:0007420(brain development);GO:0007507(heart development);GO:0008630(intrinsic apoptotic signaling pathway in response to DNA damage);GO:0010212(response to ionizing radiation);GO:0010332(response to gamma radiation);GO:0014823(response to activity);GO:0016233(telomere capping);GO:0030098(lymphocyte differentiation);GO:0031648(protein destabilization);GO:0033077(T cell differentiation in thymus);GO:0033151(V(D)J recombination);GO:0033152(immunoglobulin V(D)J recombination);GO:0033153(T cell receptor V(D)J recombination);GO:0035234(ectopic germ cell programmed cell death);GO:0043065(positive regulation of apoptotic process);GO:0048146(positive regulation of fibroblast proliferation);GO:0048536(spleen development);GO:0048538(thymus development);GO:0048639(positive regulation of developmental growth);GO:0072431(signal transduction involved in mitotic G1 DNA damage checkpoint);GO:0097681(double-strand break repair via alternative nonhomologous end joining);GO:2000773(negative regulation of cellular senescence);GO:2001229(negative regulation of response to gamma radiation)","03450(Non-homologous end-joining);04110(Cell cycle)","K06642","EC:2.7.11.1","protein kinase, DNA-activated, catalytic polypeptide [Source:HGNC Symbol;Acc:HGNC:9413]",{"v":0.36608,"d":"0.37"},{"v":3.764546,"d":"3.76"},{"v":0.097244129836639,"d":"0.10"},{"v":-3.36224502565201,"d":"-3.36"},{"v":4.07748446066757e-06,"d":"0.00"},{"v":1.95440365167909E-4,"d":"0.00"},"down","yes"]
[35664,0,"chr11","-",118193963,118213359,"ENST00000292067",9,1959,"MSTRG.2878","JAML","GO:0016021(integral component of membrane);GO:0016020(membrane);GO:0050900(leukocyte migration);GO:0046629(gamma-delta T cell activation);GO:0007155(cell adhesion);GO:0042803(protein homodimerization activity);GO:0005886(plasma membrane);GO:0030054(cell junction);GO:0002376(immune system process);GO:0050776(regulation of immune response);GO:0005923(bicellular tight junction);GO:0030593(neutrophil chemotaxis);GO:0060054(positive regulation of epithelial cell proliferation involved in wound healing);GO:0005178(integrin binding);GO:0072672(neutrophil extravasation);GO:0050839(cell adhesion molecule binding);GO:0007157(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules);GO:0035696(monocyte extravasation)","NA","NA","NA","junction adhesion molecule like [Source:HGNC Symbol;Acc:HGNC:19084]",{"v":0.938009,"d":"0.94"},{"v":9.82544,"d":"9.83"},{"v":0.0954673785601459,"d":"0.10"},{"v":-3.38884834489152,"d":"-3.39"},{"v":4.0814619528755e-06,"d":"0.00"},{"v":1.95440365167909E-4,"d":"0.00"},"down","yes"]
[118898,0,"chr2","+",216498867,216501467,"ENST00000359681",3,742,"MSTRG.9408","RPL37A","GO:0003723(RNA binding);GO:0005634(nucleus);GO:0006412(translation);GO:0046872(metal ion binding);GO:0030529(intracellular ribonucleoprotein complex);GO:0005622(intracellular);GO:0003735(structural constituent of ribosome);GO:0005840(ribosome);GO:0005515(protein binding);GO:0005925(focal adhesion);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0006413(translational initiation);GO:0006364(rRNA processing);GO:0000184(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay);GO:0019083(viral transcription);GO:0006614(SRP-dependent cotranslational protein targeting to membrane);GO:0022625(cytosolic large ribosomal subunit)","03010(Ribosome)","NA","NA","ribosomal protein L37a [Source:HGNC Symbol;Acc:HGNC:10348]",{"v":1.91166,"d":"1.91"},{"v":20.238831,"d":"20.24"},{"v":0.0944550601761534,"d":"0.09"},{"v":-3.40422810257884,"d":"-3.40"},{"v":4.10676329710766E-6,"d":"0.00"},{"v":0.000196181458173794,"d":"0.00"},"down","yes"]
[78582,0,"chr17","+",7219806,7225273,"ENST00000356839",20,2323,"MSTRG.6390","ACADVL","GO:0045717(negative regulation of fatty acid biosynthetic process);GO:0016020(membrane);GO:0005634(nucleus);GO:0005730(nucleolus);GO:0005829(cytosol);GO:0016491(oxidoreductase activity);GO:0050660(flavin adenine dinucleotide binding);GO:0055114(oxidation-reduction process);GO:0016627(oxidoreductase activity, acting on the CH-CH group of donors);GO:0005739(mitochondrion);GO:0005743(mitochondrial inner membrane);GO:0006629(lipid metabolic process);GO:0008152(metabolic process);GO:0006631(fatty acid metabolic process);GO:0003995(acyl-CoA dehydrogenase activity);GO:0005759(mitochondrial matrix);GO:0030855(epithelial cell differentiation);GO:0042645(mitochondrial nucleoid);GO:0006635(fatty acid beta-oxidation);GO:0036498(IRE1-mediated unfolded protein response);GO:0001659(temperature homeostasis);GO:0033539(fatty acid beta-oxidation using acyl-CoA dehydrogenase);GO:0004466(long-chain-acyl-CoA dehydrogenase activity);GO:0046322(negative regulation of fatty acid oxidation);GO:0090181(regulation of cholesterol metabolic process);GO:0009062(fatty acid catabolic process);GO:0009409(response to cold);GO:0015980(energy derivation by oxidation of organic compounds)","00071(Fatty acid degradation)","K09479","EC:1.3.8.9","acyl-CoA dehydrogenase, very long chain [Source:HGNC Symbol;Acc:HGNC:92]",{"v":1.013715,"d":"1.01"},{"v":10.534393,"d":"10.53"},{"v":0.0962290850550193,"d":"0.10"},{"v":-3.37738317807976,"d":"-3.38"},{"v":4.18099953082114e-06,"d":"0.00"},{"v":0.000199251070719419,"d":"0.00"},"down","yes"]
[142154,0,"chr3","+",158801865,158829719,"ENST00000415822",16,2423,"MSTRG.11310","MFSD1","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0006810(transport);GO:0055085(transmembrane transport)","NA","NA","NA","major facilitator superfamily domain containing 1 [Source:HGNC Symbol;Acc:HGNC:25874]",{"v":4.038655,"d":"4.04"},{"v":0.405076,"d":"0.41"},{"v":9.97011671883795,"d":"9.97"},{"v":3.31761039416239,"d":"3.32"},{"v":4.20619580404956E-6,"d":"0.00"},{"v":0.000199974566226814,"d":"0.00"},"up","yes"]
[66766,0,"chr15","+",94298266,94479034,"ENST00000451018",20,2472,"MSTRG.5450","MCTP2","GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0007275(multicellular organism development);GO:0005783(endoplasmic reticulum);GO:0019722(calcium-mediated signaling);GO:0005509(calcium ion binding)","NA","NA","NA","multiple C2 and transmembrane domain containing 2 [Source:HGNC Symbol;Acc:HGNC:25636]",{"v":0.670277,"d":"0.67"},{"v":7.02698,"d":"7.03"},{"v":0.0953862114307996,"d":"0.10"},{"v":-3.39007545748664,"d":"-3.39"},{"v":4.2236098850076e-06,"d":"0.00"},{"v":0.000200325515876085,"d":"0.00"},"down","yes"]
[17516,0,"chr1","-",243501763,243850128,"ENST00000366539",14,5127,"ENSG00000117020","AKT3","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0005515(protein binding);GO:0007165(signal transduction);GO:0005622(intracellular);GO:0035556(intracellular signal transduction);GO:0018105(peptidyl-serine phosphorylation);GO:0000002(mitochondrial genome maintenance);GO:0032008(positive regulation of TOR signaling);GO:0045793(positive regulation of cell size);GO:0048854(brain morphogenesis);GO:0048873(homeostasis of number of cells within a tissue)","04014(Ras signaling pathway);04015(Rap1 signaling pathway);04010(MAPK signaling pathway);04012(ErbB signaling pathway);04370(VEGF signaling pathway);04371(Apelin signaling pathway);04630(Jak-STAT signaling pathway);04668(TNF signaling pathway);04066(HIF-1 signaling pathway);04068(FoxO signaling pathway);04072(Phospholipase D signaling pathway);04071(Sphingolipid signaling pathway);04024(cAMP signaling pathway);04022(cGMP - PKG signaling pathway);04151(PI3K-Akt signaling pathway);04152(AMPK signaling pathway);04150(mTOR signaling pathway);04140(Autophagy - animal);04210(Apoptosis);04218(Cellular senescence);04510(Focal adhesion);04550(Signaling pathways regulating pluripotency of stem cells);04611(Platelet activation);04620(Toll-like receptor signaling pathway);04660(T cell receptor signaling pathway);04662(B cell receptor signaling pathway);04664(Fc epsilon RI signaling pathway);04666(Fc gamma R-mediated phagocytosis);04062(Chemokine signaling pathway);04910(Insulin signaling pathway);04922(Glucagon signaling pathway);04923(Regulation of lipolysis in adipocyte);04920(Adipocytokine signaling pathway);04915(Estrogen signaling pathway);04914(Progesterone-mediated oocyte maturation);04917(Prolactin signaling pathway);04926(Relaxin signaling pathway);04919(Thyroid hormone signaling pathway);04261(Adrenergic signaling in cardiomyocytes);04973(Carbohydrate digestion and absorption);04725(Cholinergic synapse);04728(Dopaminergic synapse);04722(Neurotrophin signaling pathway);04380(Osteoclast differentiation);04211(Longevity regulating pathway - mammal);04213(Longevity regulating pathway - multiple species);05200(Pathways in cancer);05230(Central carbon metabolism in cancer);05231(Choline metabolism in cancer);05205(Proteoglycans in cancer);05210(Colorectal cancer);05212(Pancreatic cancer);05225(Hepatocellular carcinoma);05226(Gastric cancer);05214(Glioma);05221(Acute myeloid leukemia);05220(Chronic myeloid leukemia);05218(Melanoma);05211(Renal cell carcinoma);05215(Prostate cancer);05213(Endometrial cancer);05224(Breast cancer);05222(Small cell lung cancer);05223(Non-small cell lung cancer);05418(Fluid shear stress and atherosclerosis);04932(Non-alcoholic fatty liver disease (NAFLD));04931(Insulin resistance);04933(AGE-RAGE signaling pathway in diabetic complications);05152(Tuberculosis);05166(HTLV-I infection);05162(Measles);05164(Influenza A);05161(Hepatitis B);05160(Hepatitis C);05167(Kaposi's sarcoma-associated herpesvirus infection);05169(Epstein-Barr virus infection);05165(Human papillomavirus infection);05145(Toxoplasmosis);05142(Chagas disease (American trypanosomiasis));01521(EGFR tyrosine kinase inhibitor resistance);01524(Platinum drug resistance);01522(Endocrine resistance)","K04456","EC:2.7.11.1","AKT serine/threonine kinase 3 [Source:HGNC Symbol;Acc:HGNC:393]",{"v":1.476965,"d":"1.48"},{"v":0.146771,"d":"0.15"},{"v":10.0630574159745,"d":"10.06"},{"v":3.33099679453589,"d":"3.33"},{"v":4.28256529767497e-06,"d":"0.00"},{"v":2.0264043569662E-4,"d":"0.00"},"up","yes"]
[133113,0,"chr3","+",9793095,9804214,"ENST00000467289",5,729,"MSTRG.10649","ARPC4","GO:0005737(cytoplasm);GO:0003779(actin binding);GO:0015629(actin cytoskeleton);GO:0005856(cytoskeleton);GO:0042995(cell projection);GO:0005515(protein binding);GO:0030041(actin filament polymerization);GO:0030833(regulation of actin filament polymerization);GO:0034314(Arp2/3 complex-mediated actin nucleation);GO:0005885(Arp2/3 protein complex);GO:0038096(Fc-gamma receptor signaling pathway involved in phagocytosis);GO:0005829(cytosol);GO:0051015(actin filament binding);GO:0070062(extracellular exosome);GO:0061024(membrane organization);GO:0030674(protein binding, bridging);GO:0048013(ephrin receptor signaling pathway);GO:0019899(enzyme binding);GO:0005200(structural constituent of cytoskeleton);GO:0045010(actin nucleation)","04144(Endocytosis);04810(Regulation of actin cytoskeleton);04666(Fc gamma R-mediated phagocytosis);05130(Pathogenic Escherichia coli infection);05132(Salmonella infection);05131(Shigellosis);05100(Bacterial invasion of epithelial cells)","NA","NA","actin related protein 2/3 complex subunit 4 [Source:HGNC Symbol;Acc:HGNC:707]",{"v":0.92991,"d":"0.93"},{"v":10.269765,"d":"10.27"},{"v":0.0905483231602671,"d":"0.09"},{"v":-3.4651682652284,"d":"-3.47"},{"v":4.45461080823193e-06,"d":"0.00"},{"v":2.10282904536111E-4,"d":"0.00"},"down","yes"]
[38035,0,"chr12","+",6772512,6778455,"ENST00000538079",6,2587,"ENSG00000089692","LAG3","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005886(plasma membrane);GO:0019886(antigen processing and presentation of exogenous peptide antigen via MHC class II);GO:0003823(antigen binding);GO:0042289(MHC class II protein binding);GO:0004888(transmembrane signaling receptor activity);GO:0007166(cell surface receptor signaling pathway);GO:0045085(negative regulation of interleukin-2 biosynthetic process);GO:0045954(positive regulation of natural killer cell mediated cytotoxicity);GO:0050868(negative regulation of T cell activation);GO:0009897(external side of plasma membrane)","NA","NA","NA","lymphocyte activating 3 [Source:HGNC Symbol;Acc:HGNC:6476]",{"v":4.109086,"d":"4.11"},{"v":0.417943,"d":"0.42"},{"v":9.83168996729219,"d":"9.83"},{"v":3.29743942245363,"d":"3.30"},{"v":4.47380084883966e-06,"d":"0.00"},{"v":2.10482883178457E-4,"d":"0.00"},"up","yes"]
[48160,0,"chr12","+",123973212,124015426,"ENST00000392404",5,4262,"MSTRG.3860","ZNF664","GO:0005634(nucleus);GO:0003676(nucleic acid binding);GO:0046872(metal ion binding);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0003674(molecular_function);GO:0008150(biological_process)","NA","NA","NA","zinc finger protein 664 [Source:HGNC Symbol;Acc:HGNC:25406]",{"v":5.95691,"d":"5.96"},{"v":0.628759,"d":"0.63"},{"v":9.47407512258274,"d":"9.47"},{"v":3.24398511149582,"d":"3.24"},{"v":4.47992915418891e-06,"d":"0.00"},{"v":2.10482883178457E-4,"d":"0.00"},"up","yes"]
[139942,0,"chr3","-",125225561,125375354,"ENST00000360647",9,9651,"MSTRG.11150","ZNF148","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0005794(Golgi apparatus);GO:0046872(metal ion binding);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:0001078(transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0021762(substantia nigra development);GO:0043565(sequence-specific DNA binding);GO:0010629(negative regulation of gene expression);GO:0045892(negative regulation of transcription, DNA-templated);GO:0006366(transcription from RNA polymerase II promoter);GO:0006968(cellular defense response);GO:0000976(transcription regulatory region sequence-specific DNA binding);GO:0003690(double-stranded DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0006461(protein complex assembly);GO:0007276(gamete generation);GO:0045944(positive regulation of transcription from RNA polymerase II promoter)","NA","NA","NA","zinc finger protein 148 [Source:HGNC Symbol;Acc:HGNC:12933]",{"v":0.287119,"d":"0.29"},{"v":2.943341,"d":"2.94"},{"v":0.0975486700317768,"d":"0.10"},{"v":-3.35773398635754,"d":"-3.36"},{"v":4.50910125382559e-06,"d":"0.00"},{"v":2.11356182714529E-4,"d":"0.00"},"down","yes"]
[178460,0,"chr7","-",128027071,128031070,"ENST00000249363",2,3828,"MSTRG.13945","LRRC4","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0030054(cell junction);GO:0045202(synapse);GO:0045211(postsynaptic membrane);GO:0005737(cytoplasm);GO:0004860(protein kinase inhibitor activity);GO:0006469(negative regulation of protein kinase activity);GO:0019221(cytokine-mediated signaling pathway);GO:0046426(negative regulation of JAK-STAT cascade);GO:0050807(regulation of synapse organization);GO:0050808(synapse organization);GO:0097119(postsynaptic density protein 95 clustering);GO:0043197(dendritic spine);GO:0044309(neuron spine);GO:0060076(excitatory synapse)","04514(Cell adhesion molecules (CAMs));04360(Axon guidance)","K16351","NA","leucine rich repeat containing 4 [Source:HGNC Symbol;Acc:HGNC:15586]",{"v":1.329182,"d":"1.33"},{"v":13.473285,"d":"13.47"},{"v":0.0986531495474192,"d":"0.10"},{"v":-3.34149107938433,"d":"-3.34"},{"v":4.53035433647606e-06,"d":"0.00"},{"v":0.000211613637933399,"d":"0.00"},"down","yes"]
[123348,"j","chr20","-",35701821,35742250,"MSTRG.9715.2",18,4714,"MSTRG.9715","RBM39","NA","NA","NA","NA","NA",{"v":4.018186,"d":"4.02"},{"v":0.423283,"d":"0.42"},{"v":9.49290663693085,"d":"9.49"},{"v":3.2468498942677,"d":"3.25"},{"v":4.53578911435772e-06,"d":"0.00"},{"v":0.000211613637933399,"d":"0.00"},"up","yes"]
[63818,"j","chr15","-",66500949,66504846,"MSTRG.5230.10",6,764,"MSTRG.5230","RPL4","NA","NA","NA","NA","NA",{"v":4.265806,"d":"4.27"},{"v":43.518288,"d":"43.52"},{"v":0.0980232954016941,"d":"0.10"},{"v":-3.35073154088703,"d":"-3.35"},{"v":4.56125825837149e-06,"d":"0.00"},{"v":2.12305838935109E-4,"d":"0.00"},"down","yes"]
[16788,0,"chr1","-",228393673,228405904,"ENST00000493030",5,5774,"MSTRG.1438","TRIM11","GO:0005634(nucleus);GO:0005829(cytosol);GO:0005737(cytoplasm);GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0016740(transferase activity);GO:0016567(protein ubiquitination);GO:0005622(intracellular);GO:0005515(protein binding);GO:0045087(innate immune response);GO:0051607(defense response to virus);GO:0046598(positive regulation of viral entry into host cell);GO:0046597(negative regulation of viral entry into host cell);GO:0032897(negative regulation of viral transcription);GO:1902187(negative regulation of viral release from host cell);GO:0004842(ubiquitin-protein transferase activity);GO:0008134(transcription factor binding);GO:0019904(protein domain specific binding);GO:0061630(ubiquitin protein ligase activity);GO:0045892(negative regulation of transcription, DNA-templated);GO:0050768(negative regulation of neurogenesis)","NA","NA","NA","tripartite motif containing 11 [Source:HGNC Symbol;Acc:HGNC:16281]",{"v":1.772811,"d":"1.77"},{"v":0.180157,"d":"0.18"},{"v":9.84036701321625,"d":"9.84"},{"v":3.29871212433208,"d":"3.30"},{"v":4.65124050457368e-06,"d":"0.00"},{"v":2.1572467802637E-4,"d":"0.00"},"up","yes"]
[148026,0,"chr4","-",70655544,70666631,"ENST00000543780",4,1406,"MSTRG.11653","JCHAIN","GO:0042803(protein homodimerization activity);GO:0005576(extracellular region);GO:0006955(immune response);GO:0005615(extracellular space);GO:0045087(innate immune response);GO:0003823(antigen binding);GO:0002250(adaptive immune response);GO:0006898(receptor-mediated endocytosis);GO:0050900(leukocyte migration);GO:0031210(phosphatidylcholine binding);GO:0070062(extracellular exosome);GO:0001895(retina homeostasis);GO:0072562(blood microparticle);GO:0019731(antibacterial humoral response);GO:0032461(positive regulation of protein oligomerization);GO:0003697(single-stranded DNA binding);GO:0042834(peptidoglycan binding);GO:0034987(immunoglobulin receptor binding);GO:0019862(IgA binding);GO:0030674(protein binding, bridging);GO:0003094(glomerular filtration);GO:0060267(positive regulation of respiratory burst);GO:0071748(monomeric IgA immunoglobulin complex);GO:0071750(dimeric IgA immunoglobulin complex);GO:0071751(secretory IgA immunoglobulin complex);GO:0071752(secretory dimeric IgA immunoglobulin complex);GO:0071756(pentameric IgM immunoglobulin complex)","NA","NA","NA","joining chain of multimeric IgA and IgM [Source:HGNC Symbol;Acc:HGNC:5713]",{"v":14.812922,"d":"14.81"},{"v":1.562657,"d":"1.56"},{"v":9.47931759816774,"d":"9.48"},{"v":3.24478320541312,"d":"3.24"},{"v":4.65631691853793e-06,"d":"0.00"},{"v":2.1572467802637E-4,"d":"0.00"},"up","yes"]
[41335,0,"chr12","-",49644953,49707393,"ENST00000352151",25,4006,"MSTRG.3364","FMNL3","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005794(Golgi apparatus);GO:0043231(intracellular membrane-bounded organelle);GO:0005829(cytosol);GO:0003779(actin binding);GO:0005886(plasma membrane);GO:0030036(actin cytoskeleton organization);GO:0008360(regulation of cell shape);GO:0007275(multicellular organism development);GO:0016477(cell migration);GO:0007010(cytoskeleton organization);GO:0016043(cellular component organization);GO:0017048(Rho GTPase binding);GO:0001525(angiogenesis);GO:0032794(GTPase activating protein binding)","NA","NA","NA","formin like 3 [Source:HGNC Symbol;Acc:HGNC:23698]",{"v":0.337871,"d":"0.34"},{"v":3.540407,"d":"3.54"},{"v":0.0954328132330548,"d":"0.10"},{"v":-3.38937078780849,"d":"-3.39"},{"v":4.71379606901372e-06,"d":"0.00"},{"v":0.000217573176103724,"d":"0.00"},"down","yes"]
[174595,0,"chr7","+",66114605,66154561,"ENST00000395326",6,3009,"MSTRG.13659","CRCP","GO:0005634(nucleus);GO:0016020(membrane);GO:0003824(catalytic activity);GO:0006351(transcription, DNA-templated);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0003899(DNA-directed 5'-3' RNA polymerase activity);GO:0000166(nucleotide binding);GO:0002376(immune system process);GO:0045087(innate immune response);GO:0044237(cellular metabolic process);GO:0001635(calcitonin gene-related peptide receptor activity);GO:0007218(neuropeptide signaling pathway);GO:0001669(acrosomal vesicle);GO:0051607(defense response to virus);GO:0005666(DNA-directed RNA polymerase III complex);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0001056(RNA polymerase III activity);GO:0032481(positive regulation of type I interferon production);GO:0006383(transcription from RNA polymerase III promoter);GO:0006384(transcription initiation from RNA polymerase III promoter);GO:0009360(DNA polymerase III complex)","NA","NA","NA","CGRP receptor component [Source:HGNC Symbol;Acc:HGNC:17888]",{"v":0.531869,"d":"0.53"},{"v":5.536549,"d":"5.54"},{"v":0.0960650759164238,"d":"0.10"},{"v":-3.37984414961516,"d":"-3.38"},{"v":4.71800807556654e-06,"d":"0.00"},{"v":0.000217573176103724,"d":"0.00"},"down","yes"]
[111733,0,"chr2","+",85584408,85593412,"ENST00000306384",3,689,"MSTRG.8874","VAMP5","GO:0048471(perinuclear region of cytoplasm);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016192(vesicle-mediated transport);GO:0005794(Golgi apparatus);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0007275(multicellular organism development);GO:0030154(cell differentiation);GO:0006906(vesicle fusion);GO:0070062(extracellular exosome);GO:0012505(endomembrane system);GO:0007517(muscle organ development);GO:0000149(SNARE binding);GO:0005484(SNAP receptor activity);GO:0031201(SNARE complex);GO:0006887(exocytosis);GO:0009986(cell surface);GO:0005770(late endosome);GO:0014704(intercalated disc);GO:0007519(skeletal muscle tissue development);GO:0043001(Golgi to plasma membrane protein transport);GO:0005887(integral component of plasma membrane);GO:0030659(cytoplasmic vesicle membrane);GO:0031301(integral component of organelle membrane)","04130(SNARE interactions in vesicular transport)","K08514","NA","vesicle associated membrane protein 5 [Source:HGNC Symbol;Acc:HGNC:12646]",{"v":1.191655,"d":"1.19"},{"v":12.821656,"d":"12.82"},{"v":0.0929408026545089,"d":"0.09"},{"v":-3.42754408548258,"d":"-3.43"},{"v":4.81611985122522e-06,"d":"0.00"},{"v":0.000221585901357754,"d":"0.00"},"down","yes"]
[137559,0,"chr3","+",58332948,58426019,"ENST00000479241",18,2817,"MSTRG.11019","PXK","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005829(cytosol);GO:0003779(actin binding);GO:0005886(plasma membrane);GO:0005815(microtubule organizing center);GO:0035091(phosphatidylinositol binding);GO:0006954(inflammatory response);GO:0050804(modulation of synaptic transmission);GO:0004672(protein kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation)","NA","NA","NA","PX domain containing serine/threonine kinase like [Source:HGNC Symbol;Acc:HGNC:23326]",{"v":2.769248,"d":"2.77"},{"v":0.282716,"d":"0.28"},{"v":9.79515839216741,"d":"9.80"},{"v":3.29206882171664,"d":"3.29"},{"v":4.85497473315325e-06,"d":"0.00"},{"v":0.000222860081543917,"d":"0.00"},"up","yes"]
[7118,0,"chr1","+",70205682,70251617,"ENST00000370951",13,2385,"MSTRG.647","SRSF11","GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0006397(mRNA processing);GO:0008380(RNA splicing);GO:0005634(nucleus);GO:0016607(nuclear speck);GO:0005515(protein binding);GO:0005654(nucleoplasm);GO:0006369(termination of RNA polymerase II transcription);GO:0006405(RNA export from nucleus);GO:0031124(mRNA 3'-end processing);GO:0000398(mRNA splicing, via spliceosome);GO:0006406(mRNA export from nucleus)","NA","NA","NA","serine and arginine rich splicing factor 11 [Source:HGNC Symbol;Acc:HGNC:10782]",{"v":0.264225,"d":"0.26"},{"v":2.905624,"d":"2.91"},{"v":0.0909357163900078,"d":"0.09"},{"v":-3.45900914355951,"d":"-3.46"},{"v":4.88871978160752e-06,"d":"0.00"},{"v":0.000223486176185454,"d":"0.00"},"down","yes"]
[166082,"j","chr6","+",42928680,42941142,"MSTRG.13045.1",7,4141,"MSTRG.13045","CNPY3","NA","NA","NA","NA","NA",{"v":3.126373,"d":"3.13"},{"v":31.126755,"d":"31.13"},{"v":0.100440055508517,"d":"0.10"},{"v":-3.31559336385508,"d":"-3.32"},{"v":4.89217007731574e-06,"d":"0.00"},{"v":0.000223486176185454,"d":"0.00"},"down","yes"]
[52078,0,"chr13","+",114234977,114272675,"ENST00000356221",18,2203,"ENSG00000130177","CDC16","GO:0005737(cytoplasm);GO:0016567(protein ubiquitination);GO:0051301(cell division);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0007049(cell cycle);GO:0005815(microtubule organizing center);GO:0005819(spindle);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0031145(anaphase-promoting complex-dependent catabolic process);GO:0043161(proteasome-mediated ubiquitin-dependent protein catabolic process);GO:0051437(positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition);GO:0051436(negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle);GO:0008283(cell proliferation);GO:0042787(protein ubiquitination involved in ubiquitin-dependent protein catabolic process);GO:0051439(regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle);GO:0070979(protein K11-linked ubiquitination);GO:0005680(anaphase-promoting complex);GO:0007088(regulation of mitotic nuclear division);GO:0000278(mitotic cell cycle);GO:0005813(centrosome);GO:0005876(spindle microtubule);GO:0005634(nucleus)","04120(Ubiquitin mediated proteolysis);04110(Cell cycle);04114(Oocyte meiosis);04914(Progesterone-mediated oocyte maturation);05166(HTLV-I infection)","K03353","NA","cell division cycle 16 [Source:HGNC Symbol;Acc:HGNC:1720]",{"v":3.901014,"d":"3.90"},{"v":0.395745,"d":"0.40"},{"v":9.85739301823144,"d":"9.86"},{"v":3.30120614792457,"d":"3.30"},{"v":4.90219076368333e-06,"d":"0.00"},{"v":0.000223486176185454,"d":"0.00"},"up","yes"]
[12965,0,"chr1","+",161524540,161526910,"ENST00000309758",1,2371,"MSTRG.1158","HSPA6","GO:0005737(cytoplasm);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0005829(cytosol);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0070062(extracellular exosome);GO:0005814(centriole);GO:0008180(COP9 signalosome);GO:0072562(blood microparticle);GO:0043312(neutrophil degranulation);GO:0034774(secretory granule lumen);GO:1904813(ficolin-1-rich granule lumen);GO:0051082(unfolded protein binding);GO:0019899(enzyme binding);GO:0006986(response to unfolded protein);GO:0034605(cellular response to heat);GO:0042623(ATPase activity, coupled);GO:0042026(protein refolding);GO:0031072(heat shock protein binding)","03040(Spliceosome);04141(Protein processing in endoplasmic reticulum);04010(MAPK signaling pathway);04144(Endocytosis);04612(Antigen processing and presentation);04915(Estrogen signaling pathway);04213(Longevity regulating pathway - multiple species);05134(Legionellosis);05162(Measles);05164(Influenza A);05169(Epstein-Barr virus infection);05145(Toxoplasmosis)","K03283","NA","heat shock protein family A (Hsp70) member 6 [Source:HGNC Symbol;Acc:HGNC:5239]",{"v":4.37448,"d":"4.37"},{"v":0.451455,"d":"0.45"},{"v":9.68973651858989,"d":"9.69"},{"v":3.27645743669383,"d":"3.28"},{"v":4.9761398426763e-06,"d":"0.00"},{"v":2.26340684233623E-4,"d":"0.00"},"up","yes"]
[136961,0,"chr3","-",51993629,51995844,"ENST00000495383",4,713,"MSTRG.10970","RPL29","GO:0003723(RNA binding);GO:0016020(membrane);GO:0006412(translation);GO:0030529(intracellular ribonucleoprotein complex);GO:0005622(intracellular);GO:0003735(structural constituent of ribosome);GO:0005840(ribosome);GO:0008201(heparin binding);GO:0005829(cytosol);GO:0045296(cadherin binding);GO:0002181(cytoplasmic translation);GO:0006413(translational initiation);GO:0006364(rRNA processing);GO:0000184(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay);GO:0019083(viral transcription);GO:0006614(SRP-dependent cotranslational protein targeting to membrane);GO:0022625(cytosolic large ribosomal subunit);GO:0007566(embryo implantation)","03010(Ribosome)","NA","NA","ribosomal protein L29 [Source:HGNC Symbol;Acc:HGNC:10331]",{"v":10.126623,"d":"10.13"},{"v":1.018793,"d":"1.02"},{"v":9.93982388964196,"d":"9.94"},{"v":3.3132202908428,"d":"3.31"},{"v":5.00411805843364e-06,"d":"0.00"},{"v":0.000227095975888188,"d":"0.00"},"up","yes"]
[135479,0,"chr3","+",45689262,45745424,"ENST00000389061",20,3723,"MSTRG.10869","SACM1L","GO:0042578(phosphoric ester hydrolase activity);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016787(hydrolase activity);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005515(protein binding);GO:0008150(biological_process);GO:0006661(phosphatidylinositol biosynthetic process);GO:0000139(Golgi membrane);GO:0005794(Golgi apparatus);GO:0004438(phosphatidylinositol-3-phosphatase activity);GO:0034596(phosphatidylinositol phosphate 4-phosphatase activity);GO:0016791(phosphatase activity);GO:0046856(phosphatidylinositol dephosphorylation);GO:0034593(phosphatidylinositol bisphosphate phosphatase activity);GO:0043812(phosphatidylinositol-4-phosphate phosphatase activity);GO:0030176(integral component of endoplasmic reticulum membrane);GO:0032281(AMPA glutamate receptor complex)","00562(Inositol phosphate metabolism);04070(Phosphatidylinositol signaling system)","K21797","EC:3.1.3.-","SAC1 like phosphatidylinositide phosphatase [Source:HGNC Symbol;Acc:HGNC:17059]",{"v":0.596781,"d":"0.60"},{"v":6.072186,"d":"6.07"},{"v":0.0982810803226383,"d":"0.10"},{"v":-3.346942473634,"d":"-3.35"},{"v":5.06895401669109e-06,"d":"0.00"},{"v":0.000229516720646911,"d":"0.00"},"down","yes"]
[46927,0,"chr12","+",112978395,113011723,"ENST00000342315",11,3613,"MSTRG.3740","OAS2","GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0043231(intracellular membrane-bounded organelle);GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0016740(transferase activity);GO:0005783(endoplasmic reticulum);GO:0005739(mitochondrion);GO:0005515(protein binding);GO:0006955(immune response);GO:0016779(nucleotidyltransferase activity);GO:0048471(perinuclear region of cytoplasm);GO:0006486(protein glycosylation);GO:0003725(double-stranded RNA binding);GO:0051607(defense response to virus);GO:0002376(immune system process);GO:0045087(innate immune response);GO:0009615(response to virus);GO:0006139(nucleobase-containing compound metabolic process);GO:0060333(interferon-gamma-mediated signaling pathway);GO:0060337(type I interferon signaling pathway);GO:0001730(2'-5'-oligoadenylate synthetase activity);GO:0006401(RNA catabolic process);GO:0018377(protein myristoylation)","04621(NOD-like receptor signaling pathway);05162(Measles);05164(Influenza A);05160(Hepatitis C);05168(Herpes simplex infection)","K14216","EC:2.7.7.84","2'-5'-oligoadenylate synthetase 2 [Source:HGNC Symbol;Acc:HGNC:8087]",{"v":0.507154,"d":"0.51"},{"v":5.182083,"d":"5.18"},{"v":0.097866823051657,"d":"0.10"},{"v":-3.35303632209017,"d":"-3.35"},{"v":5.11635051947727e-06,"d":"0.00"},{"v":0.000231138658762267,"d":"0.00"},"down","yes"]
[97322,0,"chr19","-",13144089,13150238,"ENST00000587230",8,1136,"MSTRG.7876","STX10","GO:0016192(vesicle-mediated transport);GO:0016020(membrane);GO:0048193(Golgi vesicle transport);GO:0006810(transport);GO:0016021(integral component of membrane);GO:0006886(intracellular protein transport);GO:0015031(protein transport);GO:0005829(cytosol);GO:0005794(Golgi apparatus);GO:0000139(Golgi membrane);GO:0048471(perinuclear region of cytoplasm);GO:0006906(vesicle fusion);GO:0005484(SNAP receptor activity);GO:0005515(protein binding);GO:0005802(trans-Golgi network);GO:0042147(retrograde transport, endosome to Golgi);GO:0031201(SNARE complex);GO:0048278(vesicle docking);GO:0019905(syntaxin binding);GO:0032588(trans-Golgi network membrane);GO:0031982(vesicle);GO:0032880(regulation of protein localization);GO:0005622(intracellular);GO:0061025(membrane fusion)","04130(SNARE interactions in vesicular transport)","K08498","NA","syntaxin 10 [Source:HGNC Symbol;Acc:HGNC:11428]",{"v":2.421518,"d":"2.42"},{"v":24.519426,"d":"24.52"},{"v":0.098759163448606,"d":"0.10"},{"v":-3.33994157376445,"d":"-3.34"},{"v":5.12849099431001e-06,"d":"0.00"},{"v":2.31164126804474E-4,"d":"0.00"},"down","yes"]
[143851,"j","chr3","+",186783305,186789967,"MSTRG.11403.2",11,3043,"MSTRG.11403","EIF4A2","NA","NA","NA","NA","NA",{"v":7.646999,"d":"7.65"},{"v":0.822986,"d":"0.82"},{"v":9.29177288556549,"d":"9.29"},{"v":3.21595389146132,"d":"3.22"},{"v":5.36208421235724e-06,"d":"0.00"},{"v":0.000241148868361147,"d":"0.00"},"up","yes"]
[196165,0,"chrX","+",24149745,24216089,"ENST00000379177",11,7558,"ENSG00000005889","ZFX","GO:0005634(nucleus);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0046872(metal ion binding);GO:0003676(nucleic acid binding);GO:0005730(nucleolus);GO:0005654(nucleoplasm);GO:0006351(transcription, DNA-templated);GO:0003713(transcription coactivator activity);GO:0007275(multicellular organism development)","NA","NA","NA","zinc finger protein, X-linked [Source:HGNC Symbol;Acc:HGNC:12869]",{"v":3.504751,"d":"3.50"},{"v":0.38013,"d":"0.38"},{"v":9.21987477968063,"d":"9.22"},{"v":3.20474715673265,"d":"3.20"},{"v":5.41054165981849e-06,"d":"0.00"},{"v":0.000242596913354017,"d":"0.00"},"up","yes"]
[7897,0,"chr1","+",89821032,89936611,"ENST00000337338",3,3950,"MSTRG.699","LRRC8D","GO:0006810(transport);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0006811(ion transport);GO:0005886(plasma membrane);GO:0005887(integral component of plasma membrane);GO:0005515(protein binding);GO:0007165(signal transduction);GO:0055085(transmembrane transport);GO:0044070(regulation of anion transport);GO:0034702(ion channel complex);GO:0005225(volume-sensitive anion channel activity);GO:0098656(anion transmembrane transport)","NA","NA","NA","leucine rich repeat containing 8 family member D [Source:HGNC Symbol;Acc:HGNC:16992]",{"v":0.161697,"d":"0.16"},{"v":1.735224,"d":"1.74"},{"v":0.0931850873431903,"d":"0.09"},{"v":-3.42375709473893,"d":"-3.42"},{"v":5.41858089723014e-06,"d":"0.00"},{"v":0.000242596913354017,"d":"0.00"},"down","yes"]
[124552,0,"chr20","-",49903391,49915508,"ENST00000289431",3,4022,"ENSG00000158480","SPATA2","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0001650(fibrillar center);GO:0005515(protein binding);GO:0007275(multicellular organism development);GO:0030154(cell differentiation);GO:0007283(spermatogenesis);GO:0003674(molecular_function)","04217(Necroptosis)","K17595","NA","spermatogenesis associated 2 [Source:HGNC Symbol;Acc:HGNC:14681]",{"v":0.236647,"d":"0.24"},{"v":2.477614,"d":"2.48"},{"v":0.0955140711991456,"d":"0.10"},{"v":-3.38814290213613,"d":"-3.39"},{"v":5.55609024390113e-06,"d":"0.00"},{"v":0.000248196890358429,"d":"0.00"},"down","yes"]
[111307,"j","chr2","+",74483086,74493987,"MSTRG.8829.3",12,2413,"MSTRG.8829","TTC31","NA","NA","NA","NA","NA",{"v":6.044434,"d":"6.04"},{"v":0.647457,"d":"0.65"},{"v":9.33565317851224,"d":"9.34"},{"v":3.22275096561525,"d":"3.22"},{"v":5.5788391265816e-06,"d":"0.00"},{"v":0.000248656829641923,"d":"0.00"},"up","yes"]
[193742,0,"chr9","-",128179214,128190834,"ENST00000491954",7,955,"MSTRG.14997","CIZ1","GO:0005634(nucleus);GO:0003676(nucleic acid binding);GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0005654(nucleoplasm);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0030332(cyclin binding);GO:0032298(positive regulation of DNA-dependent DNA replication initiation);GO:0051457(maintenance of protein location in nucleus)","NA","NA","NA","CDKN1A interacting zinc finger protein 1 [Source:HGNC Symbol;Acc:HGNC:16744]",{"v":6.975915,"d":"6.98"},{"v":0.707499,"d":"0.71"},{"v":9.85996446638087,"d":"9.86"},{"v":3.30158244738732,"d":"3.30"},{"v":5.61353028876596e-06,"d":"0.00"},{"v":0.000249645819167213,"d":"0.00"},"up","yes"]
[42505,0,"chr12","+",54498784,54542963,"ENST00000545638",31,3612,"MSTRG.3426","NCKAP1L","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0043547(positive regulation of GTPase activity);GO:0005096(GTPase activator activity);GO:0006935(chemotaxis);GO:0032147(activation of protein kinase activity);GO:0038096(Fc-gamma receptor signaling pathway involved in phagocytosis);GO:0005887(integral component of plasma membrane);GO:0030890(positive regulation of B cell proliferation);GO:0005515(protein binding);GO:0030593(neutrophil chemotaxis);GO:0070062(extracellular exosome);GO:0042102(positive regulation of T cell proliferation);GO:0043312(neutrophil degranulation);GO:0043066(negative regulation of apoptotic process);GO:0030667(secretory granule membrane);GO:0050853(B cell receptor signaling pathway);GO:0048010(vascular endothelial growth factor receptor signaling pathway);GO:0032403(protein complex binding);GO:0030838(positive regulation of actin filament polymerization);GO:0006461(protein complex assembly);GO:0030866(cortical actin cytoskeleton organization);GO:0035509(negative regulation of myosin-light-chain-phosphatase activity);GO:0042327(positive regulation of phosphorylation);GO:0101003(ficolin-1-rich granule membrane);GO:0043029(T cell homeostasis);GO:0042493(response to drug);GO:0030295(protein kinase activator activity);GO:0002262(myeloid cell homeostasis);GO:0001782(B cell homeostasis);GO:0033630(positive regulation of cell adhesion mediated by integrin);GO:0034101(erythrocyte homeostasis);GO:0045648(positive regulation of erythrocyte differentiation);GO:0090023(positive regulation of neutrophil chemotaxis);GO:0045579(positive regulation of B cell differentiation);GO:0032715(negative regulation of interleukin-6 production);GO:0060100(positive regulation of phagocytosis, engulfment);GO:0030011(maintenance of cell polarity);GO:0032700(negative regulation of interleukin-17 production);GO:0043372(positive regulation of CD4-positive, alpha-beta T cell differentiation);GO:0043378(positive regulation of CD8-positive, alpha-beta T cell differentiation);GO:0045588(positive regulation of gamma-delta T cell differentiation);GO:0045621(positive regulation of lymphocyte differentiation);GO:0048821(erythrocyte development);GO:0070358(actin polymerization-dependent cell motility);GO:0031209(SCAR complex)","04810(Regulation of actin cytoskeleton)","K05750","NA","NCK associated protein 1 like [Source:HGNC Symbol;Acc:HGNC:4862]",{"v":21.205906,"d":"21.21"},{"v":2.339948,"d":"2.34"},{"v":9.06255438155036,"d":"9.06"},{"v":3.17991774720198,"d":"3.18"},{"v":5.72499851815805e-06,"d":"0.00"},{"v":0.000254037267579067,"d":"0.00"},"up","yes"]
[10802,0,"chr1","+",151254709,151267459,"ENST00000368881",10,1333,"MSTRG.948","PSMD4","GO:0003723(RNA binding);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0005515(protein binding);GO:0000502(proteasome complex);GO:0006511(ubiquitin-dependent protein catabolic process);GO:0038095(Fc-epsilon receptor signaling pathway);GO:0005634(nucleus);GO:0042802(identical protein binding);GO:0043161(proteasome-mediated ubiquitin-dependent protein catabolic process);GO:0000165(MAPK cascade);GO:0000209(protein polyubiquitination);GO:0002223(stimulatory C-type lectin receptor signaling pathway);GO:0002479(antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent);GO:0006521(regulation of cellular amino acid metabolic process);GO:0010972(negative regulation of G2/M transition of mitotic cell cycle);GO:0016579(protein deubiquitination);GO:0031145(anaphase-promoting complex-dependent catabolic process);GO:0031146(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process);GO:0033209(tumor necrosis factor-mediated signaling pathway);GO:0038061(NIK/NF-kappaB signaling);GO:0043488(regulation of mRNA stability);GO:0043687(post-translational protein modification);GO:0050852(T cell receptor signaling pathway);GO:0051437(positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition);GO:0055085(transmembrane transport);GO:0060071(Wnt signaling pathway, planar cell polarity pathway);GO:0061418(regulation of transcription from RNA polymerase II promoter in response to hypoxia);GO:0090090(negative regulation of canonical Wnt signaling pathway);GO:0090263(positive regulation of canonical Wnt signaling pathway);GO:1902036(regulation of hematopoietic stem cell differentiation);GO:0008540(proteasome regulatory particle, base subcomplex);GO:0051436(negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle);GO:0022624(proteasome accessory complex);GO:0043248(proteasome assembly);GO:0031593(polyubiquitin binding);GO:0008134(transcription factor binding);GO:0005737(cytoplasm)","03050(Proteasome);05169(Epstein-Barr virus infection)","K03029","NA","proteasome 26S subunit, non-ATPase 4 [Source:HGNC Symbol;Acc:HGNC:9561]",{"v":1.778645,"d":"1.78"},{"v":17.784264,"d":"17.78"},{"v":0.100012291765349,"d":"0.10"},{"v":-3.32175077309599,"d":"-3.32"},{"v":5.89351094411881e-06,"d":"0.00"},{"v":0.000260934870359566,"d":"0.00"},"down","yes"]
[161107,"j","chr5","-",172767136,172771251,"MSTRG.12537.2",3,3308,"MSTRG.12537","DUSP1","NA","NA","NA","NA","NA",{"v":3.674409,"d":"3.67"},{"v":35.692757,"d":"35.69"},{"v":0.102945507963983,"d":"0.10"},{"v":-3.28004721566489,"d":"-3.28"},{"v":5.98821953780774e-06,"d":"0.00"},{"v":0.000264541521528639,"d":"0.00"},"down","yes"]
[11803,0,"chr1","-",155659446,155688573,"ENST00000368340",10,2927,"MSTRG.1062","YY1AP1","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0001650(fibrillar center);GO:0005515(protein binding);GO:0030154(cell differentiation);GO:0005654(nucleoplasm);GO:0005730(nucleolus);GO:0008283(cell proliferation);GO:0051726(regulation of cell cycle);GO:0031011(Ino80 complex)","NA","NA","NA","YY1 associated protein 1 [Source:HGNC Symbol;Acc:HGNC:30935]",{"v":0.291492,"d":"0.29"},{"v":3.055516,"d":"3.06"},{"v":0.0953986167966392,"d":"0.10"},{"v":-3.38988784131224,"d":"-3.39"},{"v":6.00160867800173e-06,"d":"0.00"},{"v":0.000264547730866089,"d":"0.00"},"down","yes"]
[158952,"j","chr5","+",139293963,139330437,"MSTRG.12384.35",15,3973,"MSTRG.12384","MATR3","NA","NA","NA","NA","NA",{"v":10.686627,"d":"10.69"},{"v":1.181352,"d":"1.18"},{"v":9.04609887654145,"d":"9.05"},{"v":3.17729576513983,"d":"3.18"},{"v":6.05137233777239E-6,"d":"0.00"},{"v":0.000265911249605805,"d":"0.00"},"up","yes"]
[145729,0,"chr4","-",6707701,6709827,"ENST00000500563",1,2127,"MSTRG.11516","MRFAP1L1","GO:0005515(protein binding);GO:0042802(identical protein binding)","NA","NA","NA","Morf4 family associated protein 1 like 1 [Source:HGNC Symbol;Acc:HGNC:28796]",{"v":1.282076,"d":"1.28"},{"v":12.723269,"d":"12.72"},{"v":0.100766241757523,"d":"0.10"},{"v":-3.31091570015868,"d":"-3.31"},{"v":6.06490184547754e-06,"d":"0.00"},{"v":0.000265911249605805,"d":"0.00"},"down","yes"]
[118899,0,"chr2","+",216499086,216501463,"ENST00000456586",4,401,"MSTRG.9408","RPL37A","GO:0003723(RNA binding);GO:0005634(nucleus);GO:0006412(translation);GO:0046872(metal ion binding);GO:0030529(intracellular ribonucleoprotein complex);GO:0005622(intracellular);GO:0003735(structural constituent of ribosome);GO:0005840(ribosome);GO:0005515(protein binding);GO:0005925(focal adhesion);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0006413(translational initiation);GO:0006364(rRNA processing);GO:0000184(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay);GO:0019083(viral transcription);GO:0006614(SRP-dependent cotranslational protein targeting to membrane);GO:0022625(cytosolic large ribosomal subunit)","03010(Ribosome)","NA","NA","ribosomal protein L37a [Source:HGNC Symbol;Acc:HGNC:10348]",{"v":4.60812,"d":"4.61"},{"v":46.003216,"d":"46.00"},{"v":0.100169518583223,"d":"0.10"},{"v":-3.31948452925808,"d":"-3.32"},{"v":6.07459292503819e-06,"d":"0.00"},{"v":0.000265911249605805,"d":"0.00"},"down","yes"]
[31987,0,"chr11","-",67435510,67438067,"ENST00000326294",2,1292,"MSTRG.2613","PTPRCAP","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005886(plasma membrane);GO:0006952(defense response)","NA","NA","NA","protein tyrosine phosphatase, receptor type C associated protein [Source:HGNC Symbol;Acc:HGNC:9667]",{"v":29.673309,"d":"29.67"},{"v":3.278583,"d":"3.28"},{"v":9.05065054018764,"d":"9.05"},{"v":3.17802149356292,"d":"3.18"},{"v":6.08580934845016e-06,"d":"0.00"},{"v":0.000265911249605805,"d":"0.00"},"up","yes"]
[134812,"j","chr3","+",38138644,38143022,"MSTRG.10812.4",5,2665,"MSTRG.10812","MYD88","NA","NA","NA","NA","NA",{"v":2.829802,"d":"2.83"},{"v":27.553974,"d":"27.55"},{"v":0.102700321920896,"d":"0.10"},{"v":-3.28348739100192,"d":"-3.28"},{"v":6.13147148694998e-06,"d":"0.00"},{"v":2.67321446837155E-4,"d":"0.00"},"down","yes"]
[163037,0,"chr6","+",16129171,16148248,"ENST00000349606",6,2796,"MSTRG.12687","MYLIP","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0046872(metal ion binding);GO:0016740(transferase activity);GO:0016567(protein ubiquitination);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0008092(cytoskeletal protein binding);GO:0007399(nervous system development);GO:0061630(ubiquitin protein ligase activity);GO:0005829(cytosol);GO:0005622(intracellular);GO:0000209(protein polyubiquitination);GO:0042787(protein ubiquitination involved in ubiquitin-dependent protein catabolic process);GO:0004842(ubiquitin-protein transferase activity);GO:0006928(movement of cell or subcellular component);GO:0032802(low-density lipoprotein particle receptor catabolic process);GO:0010989(negative regulation of low-density lipoprotein particle clearance);GO:0031648(protein destabilization);GO:0032803(regulation of low-density lipoprotein particle receptor catabolic process);GO:0042632(cholesterol homeostasis);GO:0045732(positive regulation of protein catabolic process);GO:0005856(cytoskeleton)","04979(Cholesterol metabolism)","K10637","EC:2.3.2.27","myosin regulatory light chain interacting protein [Source:HGNC Symbol;Acc:HGNC:21155]",{"v":0.695361,"d":"0.70"},{"v":6.958468,"d":"6.96"},{"v":0.0999301857822728,"d":"0.10"},{"v":-3.32293565289466,"d":"-3.32"},{"v":6.15724887189456E-6,"d":"0.00"},{"v":0.000267860447655753,"d":"0.00"},"down","yes"]
[129242,0,"chr22","+",22822658,22823289,"ENST00000620395",2,517,"MSTRG.10249","IGLV2-8","GO:0016020(membrane);GO:0005886(plasma membrane);GO:0005576(extracellular region);GO:0006508(proteolysis);GO:0006955(immune response);GO:0002376(immune system process);GO:0003823(antigen binding);GO:0002250(adaptive immune response);GO:0004252(serine-type endopeptidase activity);GO:0006898(receptor-mediated endocytosis);GO:0006956(complement activation);GO:0006958(complement activation, classical pathway);GO:0030449(regulation of complement activation);GO:0038095(Fc-epsilon receptor signaling pathway);GO:0038096(Fc-gamma receptor signaling pathway involved in phagocytosis);GO:0050776(regulation of immune response);GO:0050900(leukocyte migration)","NA","NA","NA","immunoglobulin lambda variable 2-8 [Source:HGNC Symbol;Acc:HGNC:5895]",{"v":14.658802,"d":"14.66"},{"v":1.539327,"d":"1.54"},{"v":9.52286421273712,"d":"9.52"},{"v":3.25139556135111,"d":"3.25"},{"v":6.17494431930391e-06,"d":"0.00"},{"v":0.000268046278625783,"d":"0.00"},"up","yes"]
[4299,0,"chr1","-",36393430,36397892,"ENST00000315732",2,850,"MSTRG.421","LSM10","GO:0003723(RNA binding);GO:0006397(mRNA processing);GO:0008380(RNA splicing);GO:0005634(nucleus);GO:0030529(intracellular ribonucleoprotein complex);GO:0005515(protein binding);GO:0016604(nuclear body);GO:0005654(nucleoplasm);GO:0006369(termination of RNA polymerase II transcription);GO:1900087(positive regulation of G1/S transition of mitotic cell cycle);GO:0015030(Cajal body);GO:0008334(histone mRNA metabolic process);GO:0005683(U7 snRNP);GO:0071208(histone pre-mRNA DCP binding);GO:0071209(U7 snRNA binding)","NA","NA","NA","LSM10, U7 small nuclear RNA associated [Source:HGNC Symbol;Acc:HGNC:17562]",{"v":1.13079,"d":"1.13"},{"v":11.566724,"d":"11.57"},{"v":0.0977623396218324,"d":"0.10"},{"v":-3.35457737801798,"d":"-3.35"},{"v":6.21840850377317e-06,"d":"0.00"},{"v":0.000269347464215494,"d":"0.00"},"down","yes"]
[183427,0,"chr8","+",42271389,42332455,"ENST00000520201",19,5002,"MSTRG.14332","IKBKB","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0005829(cytosol);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0042803(protein homodimerization activity);GO:0005515(protein binding);GO:0045121(membrane raft);GO:0045893(positive regulation of transcription, DNA-templated);GO:0045087(innate immune response);GO:0006954(inflammatory response);GO:0038095(Fc-epsilon receptor signaling pathway);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0019901(protein kinase binding);GO:0002223(stimulatory C-type lectin receptor signaling pathway);GO:0002479(antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent);GO:0050852(T cell receptor signaling pathway);GO:0009615(response to virus);GO:0071356(cellular response to tumor necrosis factor);GO:0009653(anatomical structure morphogenesis);GO:0051092(positive regulation of NF-kappaB transcription factor activity);GO:0007249(I-kappaB kinase/NF-kappaB signaling);GO:0035666(TRIF-dependent toll-like receptor signaling pathway);GO:0046982(protein heterodimerization activity);GO:0009898(cytoplasmic side of plasma membrane);GO:0035631(CD40 receptor complex);GO:0090002(establishment of protein localization to plasma membrane);GO:0033209(tumor necrosis factor-mediated signaling pathway);GO:0008384(IkappaB kinase activity);GO:0097110(scaffold protein binding);GO:0007252(I-kappaB phosphorylation);GO:0010803(regulation of tumor necrosis factor-mediated signaling pathway);GO:0030866(cortical actin cytoskeleton organization);GO:0035509(negative regulation of myosin-light-chain-phosphatase activity);GO:0042325(regulation of phosphorylation);GO:0042501(serine phosphorylation of STAT protein);GO:0043066(negative regulation of apoptotic process);GO:0043123(positive regulation of I-kappaB kinase/NF-kappaB signaling);GO:0051403(stress-activated MAPK cascade);GO:0070423(nucleotide-binding oligomerization domain containing signaling pathway);GO:0070498(interleukin-1-mediated signaling pathway);GO:1903140(regulation of establishment of endothelial barrier);GO:1903347(negative regulation of bicellular tight junction assembly);GO:0008385(IkappaB kinase complex)","04014(Ras signaling pathway);04010(MAPK signaling pathway);04064(NF-kappa B signaling pathway);04668(TNF signaling pathway);04068(FoxO signaling pathway);04151(PI3K-Akt signaling pathway);04150(mTOR signaling pathway);04210(Apoptosis);04620(Toll-like receptor signaling pathway);04621(NOD-like receptor signaling pathway);04622(RIG-I-like receptor signaling pathway);04623(Cytosolic DNA-sensing pathway);04660(T cell receptor signaling pathway);04658(Th1 and Th2 cell differentiation);04659(Th17 cell differentiation);04657(IL-17 signaling pathway);04662(B cell receptor signaling pathway);04062(Chemokine signaling pathway);04910(Insulin signaling pathway);04920(Adipocytokine signaling pathway);04722(Neurotrophin signaling pathway);04380(Osteoclast differentiation);05200(Pathways in cancer);05206(MicroRNAs in cancer);05212(Pancreatic cancer);05221(Acute myeloid leukemia);05220(Chronic myeloid leukemia);05215(Prostate cancer);05222(Small cell lung cancer);05418(Fluid shear stress and atherosclerosis);04930(Type II diabetes mellitus);04932(Non-alcoholic fatty liver disease (NAFLD));04931(Insulin resistance);05120(Epithelial cell signaling in Helicobacter pylori infection);05131(Shigellosis);05166(HTLV-I infection);05164(Influenza A);05161(Hepatitis B);05160(Hepatitis C);05168(Herpes simplex infection);05167(Kaposi's sarcoma-associated herpesvirus infection);05169(Epstein-Barr virus infection);05165(Human papillomavirus infection);05145(Toxoplasmosis);05142(Chagas disease (American trypanosomiasis));01523(Antifolate resistance)","NA","NA","inhibitor of nuclear factor kappa B kinase subunit beta [Source:HGNC Symbol;Acc:HGNC:5960]",{"v":2.215936,"d":"2.22"},{"v":0.235527,"d":"0.24"},{"v":9.40841602024397,"d":"9.41"},{"v":3.23395185450603,"d":"3.23"},{"v":6.27200023431477e-06,"d":"0.00"},{"v":2.70790022750266E-4,"d":"0.00"},"up","yes"]
[103748,0,"chr19","+",49085423,49108479,"ENST00000598441",10,1574,"MSTRG.8303","SNRNP70","GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0006397(mRNA processing);GO:0005634(nucleus);GO:0016607(nuclear speck);GO:0005654(nucleoplasm);GO:0030529(intracellular ribonucleoprotein complex);GO:0030619(U1 snRNA binding);GO:0005515(protein binding);GO:0005681(spliceosomal complex);GO:0005685(U1 snRNP);GO:0003729(mRNA binding);GO:0043484(regulation of RNA splicing);GO:0000398(mRNA splicing, via spliceosome);GO:0008380(RNA splicing);GO:0071011(precatalytic spliceosome);GO:0071004(U2-type prespliceosome);GO:0043462(regulation of ATPase activity);GO:0061084(negative regulation of protein refolding);GO:1904715(negative regulation of chaperone-mediated autophagy);GO:0000243(commitment complex);GO:0019013(viral nucleocapsid);GO:1990446(U1 snRNP binding);GO:0048026(positive regulation of mRNA splicing, via spliceosome);GO:0071300(cellular response to retinoic acid);GO:0071356(cellular response to tumor necrosis factor);GO:0071560(cellular response to transforming growth factor beta stimulus);GO:0005737(cytoplasm)","03040(Spliceosome)","K11093","NA","small nuclear ribonucleoprotein U1 subunit 70 [Source:HGNC Symbol;Acc:HGNC:11150]",{"v":11.509993,"d":"11.51"},{"v":1.255952,"d":"1.26"},{"v":9.16435739582404,"d":"9.16"},{"v":3.19603372262434,"d":"3.20"},{"v":6.27883516292935e-06,"d":"0.00"},{"v":2.70790022750266E-4,"d":"0.00"},"up","yes"]
[124551,0,"chr20","+",49886371,49892242,"ENST00000490250",2,4942,"ENSG00000197818","SLC9A8","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0055085(transmembrane transport);GO:0005794(Golgi apparatus);GO:0006811(ion transport);GO:0015297(antiporter activity);GO:0015299(solute:proton antiporter activity);GO:0015385(sodium:proton antiporter activity);GO:0006812(cation transport);GO:0006814(sodium ion transport);GO:0006885(regulation of pH);GO:0035725(sodium ion transmembrane transport);GO:1902600(hydrogen ion transmembrane transport);GO:0000139(Golgi membrane);GO:0051453(regulation of intracellular pH);GO:0015386(potassium:proton antiporter activity);GO:0071805(potassium ion transmembrane transport);GO:0006813(potassium ion transport)","NA","NA","NA","solute carrier family 9 member A8 [Source:HGNC Symbol;Acc:HGNC:20728]",{"v":0.332292,"d":"0.33"},{"v":3.321586,"d":"3.32"},{"v":0.10004016153729,"d":"0.10"},{"v":-3.32134880269908,"d":"-3.32"},{"v":6.34603739001503E-6,"d":"0.00"},{"v":0.000273098436646164,"d":"0.00"},"down","yes"]
[37262,"j","chr12","+",752576,912051,"MSTRG.3007.1",26,10660,"MSTRG.3007","WNK1","NA","NA","NA","NA","NA",{"v":0.647234,"d":"0.65"},{"v":6.27808,"d":"6.28"},{"v":0.103094258117131,"d":"0.10"},{"v":-3.2779641115181,"d":"-3.28"},{"v":6.36911164590862e-06,"d":"0.00"},{"v":2.73501981388179E-4,"d":"0.00"},"down","yes"]
[158987,0,"chr5","-",139387568,139389914,"ENST00000302125",4,825,"MSTRG.12358","MZB1","GO:0005737(cytoplasm);GO:0005783(endoplasmic reticulum);GO:0005576(extracellular region);GO:0006915(apoptotic process);GO:0005788(endoplasmic reticulum lumen);GO:0042127(regulation of cell proliferation);GO:0033622(integrin activation);GO:0034663(endoplasmic reticulum chaperone complex);GO:0002642(positive regulation of immunoglobulin biosynthetic process);GO:0030888(regulation of B cell proliferation);GO:2001274(negative regulation of glucose import in response to insulin stimulus);GO:0008284(positive regulation of cell proliferation)","NA","NA","NA","marginal zone B and B1 cell specific protein [Source:HGNC Symbol;Acc:HGNC:30125]",{"v":10.201616,"d":"10.20"},{"v":1.072602,"d":"1.07"},{"v":9.511091719016,"d":"9.51"},{"v":3.24961094857414,"d":"3.25"},{"v":6.48156678725234e-06,"d":"0.00"},{"v":0.000277733745939602,"d":"0.00"},"up","yes"]
[69988,0,"chr16","-",15594386,15643166,"ENST00000396368",27,7743,"MSTRG.5695","MARF1","GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0016020(membrane);GO:0005794(Golgi apparatus);GO:0043231(intracellular membrane-bounded organelle);GO:0051321(meiotic cell cycle);GO:0030154(cell differentiation);GO:0005777(peroxisome);GO:0010468(regulation of gene expression);GO:0003674(molecular_function);GO:0010923(negative regulation of phosphatase activity);GO:0048477(oogenesis);GO:0007143(female meiotic nuclear division);GO:0006302(double-strand break repair)","NA","NA","NA","meiosis regulator and mRNA stability factor 1 [Source:HGNC Symbol;Acc:HGNC:29562]",{"v":11.70999,"d":"11.71"},{"v":1.31627,"d":"1.32"},{"v":8.8963434553701,"d":"8.90"},{"v":3.15321248632967,"d":"3.15"},{"v":6.53367218021546e-06,"d":"0.00"},{"v":0.000279366950951911,"d":"0.00"},"up","yes"]
[115651,0,"chr2","-",159768853,159798242,"ENST00000259053",6,3741,"MSTRG.9190","CD302","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0030246(carbohydrate binding);GO:0042995(cell projection);GO:0007165(signal transduction);GO:0004888(transmembrane signaling receptor activity);GO:0005887(integral component of plasma membrane);GO:0030175(filopodium);GO:0005938(cell cortex);GO:0005902(microvillus);GO:0006909(phagocytosis)","NA","NA","NA","CD302 molecule [Source:HGNC Symbol;Acc:HGNC:30843]",{"v":0.660045,"d":"0.66"},{"v":6.496836,"d":"6.50"},{"v":0.101594837856458,"d":"0.10"},{"v":-3.29910099580967,"d":"-3.30"},{"v":6.58065539304086e-06,"d":"0.00"},{"v":0.000280774630103077,"d":"0.00"},"down","yes"]
[25662,0,"chr11","-",3826978,3840983,"ENST00000351018",2,1319,"MSTRG.2130","RHOG","GO:0016020(membrane);GO:0005525(GTP binding);GO:0007264(small GTPase mediated signal transduction);GO:0000166(nucleotide binding);GO:0003924(GTPase activity);GO:0005622(intracellular);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0005925(focal adhesion);GO:0005789(endoplasmic reticulum membrane);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0051056(regulation of small GTPase mediated signal transduction);GO:0090630(activation of GTPase activity);GO:0043312(neutrophil degranulation);GO:0007266(Rho protein signal transduction);GO:0030667(secretory granule membrane);GO:0030168(platelet activation);GO:0060326(cell chemotaxis);GO:0045893(positive regulation of transcription, DNA-templated);GO:0008284(positive regulation of cell proliferation);GO:0090004(positive regulation of establishment of protein localization to plasma membrane);GO:0016601(Rac protein signal transduction);GO:0030036(actin cytoskeleton organization);GO:1900027(regulation of ruffle assembly)","05132(Salmonella infection);05131(Shigellosis);05100(Bacterial invasion of epithelial cells)","K07863","NA","ras homolog family member G [Source:HGNC Symbol;Acc:HGNC:672]",{"v":62.493805,"d":"62.49"},{"v":7.080181,"d":"7.08"},{"v":8.82658296447506,"d":"8.83"},{"v":3.14185503534729,"d":"3.14"},{"v":7.00301263570306e-06,"d":"0.00"},{"v":0.000298158115798974,"d":"0.00"},"up","yes"]
[67996,0,"chr16","+",1773326,1780627,"ENST00000570069",7,5613,"MSTRG.5520","EME2","GO:0005634(nucleus);GO:0016787(hydrolase activity);GO:0003677(DNA binding);GO:0006281(DNA repair);GO:0090305(nucleic acid phosphodiester bond hydrolysis);GO:0006310(DNA recombination);GO:0006974(cellular response to DNA damage stimulus);GO:0004519(endonuclease activity);GO:0004518(nuclease activity);GO:0000712(resolution of meiotic recombination intermediates);GO:0031297(replication fork processing);GO:0000790(nuclear chromatin);GO:0008821(crossover junction endodeoxyribonuclease activity);GO:0006302(double-strand break repair);GO:0031573(intra-S DNA damage checkpoint);GO:0048476(Holliday junction resolvase complex)","03460(Fanconi anemia pathway)","NA","NA","essential meiotic structure-specific endonuclease subunit 2 [Source:HGNC Symbol;Acc:HGNC:27289]",{"v":0.132184,"d":"0.13"},{"v":1.358315,"d":"1.36"},{"v":0.0973146876829012,"d":"0.10"},{"v":-3.36119862271167,"d":"-3.36"},{"v":7.19938152542856e-06,"d":"0.00"},{"v":0.000305866489999484,"d":"0.00"},"down","yes"]
[116543,"j","chr2","-",174532449,174634903,"MSTRG.9248.1",11,2466,"MSTRG.9248","WIPF1","NA","NA","NA","NA","NA",{"v":9.31403,"d":"9.31"},{"v":1.041967,"d":"1.04"},{"v":8.93889153879154,"d":"8.94"},{"v":3.16009594207566,"d":"3.16"},{"v":7.24403507034974e-06,"d":"0.00"},{"v":0.000307061945196917,"d":"0.00"},"up","yes"]
[63373,0,"chr15","+",63189603,63263596,"ENST00000559927",9,755,"MSTRG.5168","RAB8B","GO:0006810(transport);GO:0016020(membrane);GO:0015031(protein transport);GO:0043231(intracellular membrane-bounded organelle);GO:0005525(GTP binding);GO:0000166(nucleotide binding);GO:0005654(nucleoplasm);GO:0003924(GTPase activity);GO:0005886(plasma membrane);GO:0016604(nuclear body);GO:0031410(cytoplasmic vesicle);GO:0005778(peroxisomal membrane);GO:0005515(protein binding);GO:0070062(extracellular exosome);GO:0030670(phagocytic vesicle membrane);GO:0061024(membrane organization);GO:0005768(endosome);GO:0009306(protein secretion);GO:0005102(receptor binding);GO:0019003(GDP binding);GO:0045335(phagocytic vesicle);GO:0008021(synaptic vesicle);GO:0019882(antigen processing and presentation);GO:0055038(recycling endosome membrane);GO:0072659(protein localization to plasma membrane);GO:0030667(secretory granule membrane);GO:0034332(adherens junction organization);GO:0045046(protein import into peroxisome membrane);GO:0006904(vesicle docking involved in exocytosis);GO:0017157(regulation of exocytosis);GO:0030911(TPR domain binding);GO:0031346(positive regulation of cell projection organization);GO:0051461(positive regulation of corticotropin secretion);GO:0005739(mitochondrion);GO:0048471(perinuclear region of cytoplasm);GO:0051286(cell tip)","04530(Tight junction)","NA","NA","RAB8B, member RAS oncogene family [Source:HGNC Symbol;Acc:HGNC:30273]",{"v":1.249692,"d":"1.25"},{"v":12.617289,"d":"12.62"},{"v":0.0990459995011607,"d":"0.10"},{"v":-3.33575748438628,"d":"-3.34"},{"v":7.25827514688225e-06,"d":"0.00"},{"v":0.000307061945196917,"d":"0.00"},"down","yes"]
[201162,0,"chrX","-",154348784,154371288,"ENST00000344736",45,7932,"MSTRG.15504","FLNA","GO:0051015(actin filament binding);GO:0003779(actin binding);GO:0005737(cytoplasm);GO:0003723(RNA binding);GO:0005634(nucleus);GO:0016020(membrane);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0015629(actin cytoskeleton);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0004871(signal transducer activity);GO:0005925(focal adhesion);GO:0005576(extracellular region);GO:0060271(cilium assembly);GO:0045296(cadherin binding);GO:0070062(extracellular exosome);GO:0030030(cell projection organization);GO:0005938(cell cortex);GO:0031012(extracellular matrix);GO:0043123(positive regulation of I-kappaB kinase/NF-kappaB signaling);GO:0030334(regulation of cell migration);GO:0042803(protein homodimerization activity);GO:0044325(ion channel binding);GO:0070527(platelet aggregation);GO:0002576(platelet degranulation);GO:0008134(transcription factor binding);GO:0001664(G-protein coupled receptor binding);GO:0030168(platelet activation);GO:0043433(negative regulation of sequence-specific DNA binding transcription factor activity);GO:0042993(positive regulation of transcription factor import into nucleus);GO:0005911(cell-cell junction);GO:0050821(protein stabilization);GO:0043113(receptor clustering);GO:0044319(wound healing, spreading of cells);GO:0005730(nucleolus);GO:0030018(Z disc);GO:0017048(Rho GTPase binding);GO:0019900(kinase binding);GO:1901381(positive regulation of potassium ion transmembrane transport);GO:0015459(potassium channel regulator activity);GO:0051020(GTPase binding);GO:0048365(Rac GTPase binding);GO:0031267(small GTPase binding);GO:0043066(negative regulation of apoptotic process);GO:0051220(cytoplasmic sequestering of protein);GO:0072659(protein localization to plasma membrane);GO:0031532(actin cytoskeleton reorganization);GO:0034394(protein localization to cell surface);GO:0031941(filamentous actin);GO:0017160(Ral GTPase binding);GO:0034988(Fc-gamma receptor I complex binding);GO:0007195(adenylate cyclase-inhibiting dopamine receptor signaling pathway);GO:0016479(negative regulation of transcription from RNA polymerase I promoter);GO:0034329(cell junction assembly);GO:0042177(negative regulation of protein catabolic process);GO:0045184(establishment of protein localization);GO:0051764(actin crosslink formation);GO:0071526(semaphorin-plexin signaling pathway);GO:0090307(mitotic spindle assembly);GO:1900026(positive regulation of substrate adhesion-dependent cell spreading);GO:1905000(regulation of membrane repolarization during atrial cardiac muscle cell action potential);GO:1905031(regulation of membrane repolarization during cardiac muscle cell action potential);GO:2001046(positive regulation of integrin-mediated signaling pathway);GO:0031523(Myb complex);GO:0031852(mu-type opioid receptor binding);GO:0032403(protein complex binding);GO:0046332(SMAD binding);GO:0021943(formation of radial glial scaffolds);GO:0021987(cerebral cortex development);GO:0042789(mRNA transcription from RNA polymerase II promoter);GO:2000179(positive regulation of neural precursor cell proliferation);GO:2001224(positive regulation of neuron migration);GO:0005884(actin filament);GO:0030863(cortical cytoskeleton);GO:0043025(neuronal cell body);GO:0043198(dendritic shaft);GO:0043234(protein complex);GO:0048471(perinuclear region of cytoplasm);GO:0097440(apical dendrite)","04010(MAPK signaling pathway);04510(Focal adhesion);05205(Proteoglycans in cancer);05132(Salmonella infection)","K04437","NA","filamin A [Source:HGNC Symbol;Acc:HGNC:3754]",{"v":1.259133,"d":"1.26"},{"v":11.989531,"d":"11.99"},{"v":0.105019370649277,"d":"0.11"},{"v":-3.2512726397369,"d":"-3.25"},{"v":7.30028096798163e-06,"d":"0.00"},{"v":0.000308186068432679,"d":"0.00"},"down","yes"]
[160464,0,"chr5","+",157180843,157255099,"ENST00000519402",16,5869,"MSTRG.12490","ITK","GO:0005622(intracellular);GO:0035556(intracellular signal transduction);GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0004713(protein tyrosine kinase activity);GO:0005515(protein binding);GO:0004715(non-membrane spanning protein tyrosine kinase activity);GO:0002376(immune system process);GO:0002250(adaptive immune response);GO:0038095(Fc-epsilon receptor signaling pathway);GO:0045087(innate immune response);GO:0001816(cytokine production);GO:0005829(cytosol);GO:0050852(T cell receptor signaling pathway);GO:0007165(signal transduction);GO:0042127(regulation of cell proliferation);GO:0042110(T cell activation);GO:0006968(cellular defense response);GO:0038083(peptidyl-tyrosine autophosphorylation);GO:0031234(extrinsic component of cytoplasmic side of plasma membrane);GO:0007169(transmembrane receptor protein tyrosine kinase signaling pathway);GO:0007202(activation of phospholipase C activity);GO:0001865(NK T cell differentiation);GO:0032609(interferon-gamma production);GO:0032633(interleukin-4 production);GO:0005911(cell-cell junction)","04660(T cell receptor signaling pathway);04670(Leukocyte transendothelial migration);04062(Chemokine signaling pathway)","NA","NA","IL2 inducible T-cell kinase [Source:HGNC Symbol;Acc:HGNC:6171]",{"v":0.333584,"d":"0.33"},{"v":3.263939,"d":"3.26"},{"v":0.10220289043392,"d":"0.10"},{"v":-3.2904920966968,"d":"-3.29"},{"v":7.32750160361897e-06,"d":"0.00"},{"v":0.000308682599200556,"d":"0.00"},"down","yes"]
[54320,0,"chr14","-",35401540,35404746,"ENST00000557140",6,1400,"MSTRG.4322","NFKBIA","GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0038095(Fc-epsilon receptor signaling pathway);GO:0042802(identical protein binding);GO:0002223(stimulatory C-type lectin receptor signaling pathway);GO:0016579(protein deubiquitination);GO:0050852(T cell receptor signaling pathway);GO:0016032(viral process);GO:0031625(ubiquitin protein ligase binding);GO:0008134(transcription factor binding);GO:0019899(enzyme binding);GO:0006915(apoptotic process);GO:0042994(cytoplasmic sequestering of transcription factor);GO:0043066(negative regulation of apoptotic process);GO:0051092(positive regulation of NF-kappaB transcription factor activity);GO:0007249(I-kappaB kinase/NF-kappaB signaling);GO:0051059(NF-kappaB binding);GO:0032270(positive regulation of cellular protein metabolic process);GO:0010745(negative regulation of macrophage derived foam cell differentiation);GO:0010875(positive regulation of cholesterol efflux);GO:0010888(negative regulation of lipid storage);GO:0005622(intracellular);GO:0043392(negative regulation of DNA binding);GO:0033256(I-kappaB/NF-kappaB complex);GO:0042345(regulation of NF-kappaB import into nucleus);GO:0008139(nuclear localization sequence binding);GO:0031072(heat shock protein binding);GO:0032403(protein complex binding);GO:0000060(protein import into nucleus, translocation);GO:0007253(cytoplasmic sequestering of NF-kappaB);GO:0010468(regulation of gene expression);GO:0031663(lipopolysaccharide-mediated signaling pathway);GO:0032088(negative regulation of NF-kappaB transcription factor activity);GO:0032495(response to muramyl dipeptide);GO:0032496(response to lipopolysaccharide);GO:0033209(tumor necrosis factor-mediated signaling pathway);GO:0034142(toll-like receptor 4 signaling pathway);GO:0035994(response to muscle stretch);GO:0042127(regulation of cell proliferation);GO:0043330(response to exogenous dsRNA);GO:0045638(negative regulation of myeloid cell differentiation);GO:0045746(negative regulation of Notch signaling pathway);GO:0045893(positive regulation of transcription, DNA-templated);GO:0050729(positive regulation of inflammatory response);GO:0070417(cellular response to cold);GO:0070427(nucleotide-binding oligomerization domain containing 1 signaling pathway);GO:0070431(nucleotide-binding oligomerization domain containing 2 signaling pathway);GO:0071345(cellular response to cytokine stimulus);GO:0071407(cellular response to organic cyclic compound);GO:0097421(liver regeneration);GO:0043234(protein complex)","04064(NF-kappa B signaling pathway);04668(TNF signaling pathway);04024(cAMP signaling pathway);04210(Apoptosis);04620(Toll-like receptor signaling pathway);04621(NOD-like receptor signaling pathway);04622(RIG-I-like receptor signaling pathway);04623(Cytosolic DNA-sensing pathway);04660(T cell receptor signaling pathway);04658(Th1 and Th2 cell differentiation);04659(Th17 cell differentiation);04657(IL-17 signaling pathway);04662(B cell receptor signaling pathway);04062(Chemokine signaling pathway);04920(Adipocytokine signaling pathway);04926(Relaxin signaling pathway);04722(Neurotrophin signaling pathway);04380(Osteoclast differentiation);05200(Pathways in cancer);05203(Viral carcinogenesis);05220(Chronic myeloid leukemia);05215(Prostate cancer);05222(Small cell lung cancer);04931(Insulin resistance);05120(Epithelial cell signaling in Helicobacter pylori infection);05131(Shigellosis);05134(Legionellosis);05166(HTLV-I infection);05162(Measles);05164(Influenza A);05161(Hepatitis B);05160(Hepatitis C);05168(Herpes simplex infection);05167(Kaposi's sarcoma-associated herpesvirus infection);05169(Epstein-Barr virus infection);05145(Toxoplasmosis);05140(Leishmaniasis);05142(Chagas disease (American trypanosomiasis))","NA","NA","NFKB inhibitor alpha [Source:HGNC Symbol;Acc:HGNC:7797]",{"v":0.49917,"d":"0.50"},{"v":5.16901,"d":"5.17"},{"v":0.0965697493330444,"d":"0.10"},{"v":-3.37228485704944,"d":"-3.37"},{"v":7.57543298438471e-06,"d":"0.00"},{"v":0.000318023842469546,"d":"0.00"},"down","yes"]
[150572,0,"chr4","+",122239965,122276189,"ENST00000446180",22,4476,"MSTRG.11834","KIAA1109","GO:0005634(nucleus);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005515(protein binding);GO:0001558(regulation of cell growth);GO:0030856(regulation of epithelial cell differentiation)","NA","NA","NA","KIAA1109 [Source:HGNC Symbol;Acc:HGNC:26953]",{"v":2.634084,"d":"2.63"},{"v":0.28873,"d":"0.29"},{"v":9.12300072732311,"d":"9.12"},{"v":3.18950843210745,"d":"3.19"},{"v":7.58109720630529e-06,"d":"0.00"},{"v":0.000318023842469546,"d":"0.00"},"up","yes"]
[37263,"j","chr12","+",752576,912051,"MSTRG.3007.3",25,10573,"MSTRG.3007","WNK1","NA","NA","NA","NA","NA",{"v":0.559766,"d":"0.56"},{"v":5.30998,"d":"5.31"},{"v":0.105417722853947,"d":"0.11"},{"v":-3.24581066127018,"d":"-3.25"},{"v":7.70420854842817E-6,"d":"0.00"},{"v":0.000322510767914075,"d":"0.00"},"down","yes"]
[85665,"j","chr17","+",50719613,50750952,"MSTRG.7029.12",12,2029,"MSTRG.7029","LUC7L3","NA","NA","NA","NA","NA",{"v":0.967242,"d":"0.97"},{"v":9.377724,"d":"9.38"},{"v":0.103142510912029,"d":"0.10"},{"v":-3.27728902269174,"d":"-3.28"},{"v":7.72542551255564e-06,"d":"0.00"},{"v":0.000322614718828343,"d":"0.00"},"down","yes"]
[2046,0,"chr1","-",16562319,16613487,"ENST00000430580",29,5932,"ENSG00000219481","NBPF1","GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process)","NA","NA","NA","NBPF member 1 [Source:HGNC Symbol;Acc:HGNC:26088]",{"v":1.568307,"d":"1.57"},{"v":0.170416,"d":"0.17"},{"v":9.20281546333677,"d":"9.20"},{"v":3.20207529960428,"d":"3.20"},{"v":7.73900492381692e-06,"d":"0.00"},{"v":0.000322614718828343,"d":"0.00"},"up","yes"]
[43403,0,"chr12","-",57472264,57479632,"ENST00000424809",16,2569,"MSTRG.3490","ARHGAP9","GO:0007165(signal transduction);GO:0043547(positive regulation of GTPase activity);GO:0005515(protein binding);GO:0005096(GTPase activator activity);GO:0005576(extracellular region);GO:0008289(lipid binding);GO:0005829(cytosol);GO:0051056(regulation of small GTPase mediated signal transduction);GO:0005547(phosphatidylinositol-3,4,5-trisphosphate binding);GO:0043312(neutrophil degranulation);GO:0034774(secretory granule lumen)","NA","NA","NA","Rho GTPase activating protein 9 [Source:HGNC Symbol;Acc:HGNC:14130]",{"v":0.904708,"d":"0.90"},{"v":8.691678,"d":"8.69"},{"v":0.104088991791919,"d":"0.10"},{"v":-3.26411059423248,"d":"-3.26"},{"v":7.85224505128097e-06,"d":"0.00"},{"v":0.000326653394133288,"d":"0.00"},"down","yes"]
[173579,0,"chr7","-",44072256,44082511,"ENST00000458246",10,3218,"MSTRG.13627","POLM","GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0016740(transferase activity);GO:0003677(DNA binding);GO:0006281(DNA repair);GO:0005515(protein binding);GO:0006310(DNA recombination);GO:0006974(cellular response to DNA damage stimulus);GO:0016779(nucleotidyltransferase activity);GO:0003887(DNA-directed DNA polymerase activity);GO:0071897(DNA biosynthetic process);GO:0005654(nucleoplasm);GO:0034061(DNA polymerase activity);GO:0006303(double-strand break repair via nonhomologous end joining);GO:0016446(somatic hypermutation of immunoglobulin genes);GO:0030183(B cell differentiation)","03450(Non-homologous end-joining)","K03513","EC:2.7.7.7","DNA polymerase mu [Source:HGNC Symbol;Acc:HGNC:9185]",{"v":0.207942,"d":"0.21"},{"v":2.172362,"d":"2.17"},{"v":0.0957216154581971,"d":"0.10"},{"v":-3.3850114448638,"d":"-3.39"},{"v":7.89678137805271e-06,"d":"0.00"},{"v":3.27823140451053E-4,"d":"0.00"},"down","yes"]
[38831,0,"chr12","-",10372353,10390018,"ENST00000240618",8,1553,"MSTRG.3171","KLRK1","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0030246(carbohydrate binding);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0030154(cell differentiation);GO:0002376(immune system process);GO:0045087(innate immune response);GO:0032394(MHC class Ib receptor activity);GO:0042288(MHC class I protein binding);GO:0042803(protein homodimerization activity);GO:0002223(stimulatory C-type lectin receptor signaling pathway);GO:0030101(natural killer cell activation);GO:0032729(positive regulation of interferon-gamma production);GO:0045429(positive regulation of nitric oxide biosynthetic process);GO:0045954(positive regulation of natural killer cell mediated cytotoxicity);GO:0050830(defense response to Gram-positive bacterium);GO:0071222(cellular response to lipopolysaccharide);GO:0009897(external side of plasma membrane);GO:0009986(cell surface);GO:0002250(adaptive immune response);GO:0050776(regulation of immune response);GO:0004872(receptor activity);GO:0005887(integral component of plasma membrane);GO:0007165(signal transduction);GO:0031295(T cell costimulation);GO:0034260(negative regulation of GTPase activity);GO:0042267(natural killer cell mediated cytotoxicity);GO:2000502(negative regulation of natural killer cell chemotaxis)","04650(Natural killer cell mediated cytotoxicity);05144(Malaria)","K06728","NA","killer cell lectin like receptor K1 [Source:HGNC Symbol;Acc:HGNC:18788]",{"v":0.654315,"d":"0.65"},{"v":6.562302,"d":"6.56"},{"v":0.0997081511945046,"d":"0.10"},{"v":-3.32614473924157,"d":"-3.33"},{"v":7.97987017148069e-06,"d":"0.00"},{"v":0.000330585160962918,"d":"0.00"},"down","yes"]
[181918,"j","chr8","+",22056820,22082525,"MSTRG.14210.13",16,2768,"MSTRG.14210","DMTN","NA","NA","NA","NA","NA",{"v":28.2931,"d":"28.29"},{"v":3.255788,"d":"3.26"},{"v":8.69009284388296,"d":"8.69"},{"v":3.11937159069836,"d":"3.12"},{"v":8.01660677034298e-06,"d":"0.00"},{"v":0.000331419469959024,"d":"0.00"},"up","yes"]
[132467,0,"chr22","-",50245183,50251385,"ENST00000216271",20,2687,"MSTRG.10602","HDAC10","GO:0016787(hydrolase activity);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0004407(histone deacetylase activity);GO:0032041(NAD-dependent histone deacetylase activity (H3-K14 specific));GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0016569(covalent chromatin modification);GO:0070932(histone H3 deacetylation);GO:0006476(protein deacetylation);GO:0005654(nucleoplasm);GO:0006325(chromatin organization);GO:0005515(protein binding);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0000118(histone deacetylase complex);GO:0019899(enzyme binding);GO:0045892(negative regulation of transcription, DNA-templated);GO:0033558(protein deacetylase activity);GO:0042826(histone deacetylase binding);GO:0016575(histone deacetylation);GO:0014003(oligodendrocyte development)","05203(Viral carcinogenesis);05034(Alcoholism);05165(Human papillomavirus infection)","K18671","EC:3.5.1.98","histone deacetylase 10 [Source:HGNC Symbol;Acc:HGNC:18128]",{"v":3.918636,"d":"3.92"},{"v":0.43015,"d":"0.43"},{"v":9.10992909450192,"d":"9.11"},{"v":3.18743982511311,"d":"3.19"},{"v":8.04720912838281e-06,"d":"0.00"},{"v":3.31997255941215E-4,"d":"0.00"},"up","yes"]
[62795,0,"chr15","-",55359018,55408052,"ENST00000569205",8,2970,"MSTRG.5103","CCPG1","GO:2001106(regulation of Rho guanyl-nucleotide exchange factor activity);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0007049(cell cycle);GO:0003674(molecular_function);GO:0008284(positive regulation of cell proliferation);GO:0005515(protein binding);GO:0045787(positive regulation of cell cycle);GO:0045944(positive regulation of transcription from RNA polymerase II promoter)","NA","NA","NA","cell cycle progression 1 [Source:HGNC Symbol;Acc:HGNC:24227]",{"v":0.820044,"d":"0.82"},{"v":7.861044,"d":"7.86"},{"v":0.10431744180544,"d":"0.10"},{"v":-3.26094769923046,"d":"-3.26"},{"v":8.12863950814667e-06,"d":"0.00"},{"v":0.000333806328852978,"d":"0.00"},"down","yes"]
[123599,0,"chr20","+",37694006,37872129,"ENST00000361383",16,1925,"MSTRG.9733","CTNNBL1","GO:0006397(mRNA processing);GO:0008380(RNA splicing);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005654(nucleoplasm);GO:0005515(protein binding);GO:0005681(spliceosomal complex);GO:0006915(apoptotic process);GO:0043065(positive regulation of apoptotic process);GO:0019899(enzyme binding);GO:0000398(mRNA splicing, via spliceosome);GO:0000974(Prp19 complex);GO:0016445(somatic diversification of immunoglobulins)","03040(Spliceosome)","K12864","NA","catenin beta like 1 [Source:HGNC Symbol;Acc:HGNC:15879]",{"v":0.337293,"d":"0.34"},{"v":3.441279,"d":"3.44"},{"v":0.0980138489207065,"d":"0.10"},{"v":-3.35087057975471,"d":"-3.35"},{"v":8.13668904977314e-06,"d":"0.00"},{"v":0.000333806328852978,"d":"0.00"},"down","yes"]
[87315,"j","chr17","+",68413554,68532770,"MSTRG.7157.10",11,3715,"MSTRG.7157","PRKAR1A","NA","NA","NA","NA","NA",{"v":3.431484,"d":"3.43"},{"v":0.383376,"d":"0.38"},{"v":8.95070113935145,"d":"8.95"},{"v":3.16200069809152,"d":"3.16"},{"v":8.14121004363985e-06,"d":"0.00"},{"v":0.000333806328852978,"d":"0.00"},"up","yes"]
[47962,0,"chr12","+",122980060,122982913,"ENST00000543566",6,1591,"MSTRG.3844","ARL6IP4","GO:0003723(RNA binding);GO:0006397(mRNA processing);GO:0008380(RNA splicing);GO:0005634(nucleus);GO:0016607(nuclear speck);GO:0005515(protein binding);GO:0005730(nucleolus)","NA","NA","NA","ADP ribosylation factor like GTPase 6 interacting protein 4 [Source:HGNC Symbol;Acc:HGNC:18076]",{"v":5.999014,"d":"6.00"},{"v":0.657468,"d":"0.66"},{"v":9.1244197436225,"d":"9.12"},{"v":3.18973281536046,"d":"3.19"},{"v":8.31090589715367e-06,"d":"0.00"},{"v":0.000340065919988452,"d":"0.00"},"up","yes"]
[56303,"j","chr14","+",69653237,69714449,"MSTRG.4500.3",5,5603,"MSTRG.4500","SUSD6","NA","NA","NA","NA","NA",{"v":2.199574,"d":"2.20"},{"v":20.484533,"d":"20.48"},{"v":0.107377307551995,"d":"0.11"},{"v":-3.21923895949057,"d":"-3.22"},{"v":8.52486694228435e-06,"d":"0.00"},{"v":0.000348107450109476,"d":"0.00"},"down","yes"]
[128680,0,"chr22","+",20085822,20111872,"ENST00000407755",12,4129,"MSTRG.10147","DGCR8","GO:0003723(RNA binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0005515(protein binding);GO:0090501(RNA phosphodiester bond hydrolysis);GO:0090502(RNA phosphodiester bond hydrolysis, endonucleolytic);GO:0005730(nucleolus);GO:0005654(nucleoplasm);GO:0005737(cytoplasm);GO:0042803(protein homodimerization activity);GO:0003725(double-stranded RNA binding);GO:0020037(heme binding);GO:0010586(miRNA metabolic process);GO:0070878(primary miRNA binding);GO:0031053(primary miRNA processing);GO:0004525(ribonuclease III activity);GO:0072091(regulation of stem cell proliferation);GO:0070877(microprocessor complex)","NA","NA","NA","DGCR8, microprocessor complex subunit [Source:HGNC Symbol;Acc:HGNC:2847]",{"v":0.244764,"d":"0.24"},{"v":2.411819,"d":"2.41"},{"v":0.101485227539878,"d":"0.10"},{"v":-3.30065835472826,"d":"-3.30"},{"v":8.82208843083947e-06,"d":"0.00"},{"v":0.00035950910568776,"d":"0.00"},"down","yes"]
[97540,0,"chr19","+",14381444,14408721,"ENST00000242786",20,3188,"MSTRG.7900","ADGRE5","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0004930(G-protein coupled receptor activity);GO:0007186(G-protein coupled receptor signaling pathway);GO:0005509(calcium ion binding);GO:0007155(cell adhesion);GO:0005886(plasma membrane);GO:0004871(signal transducer activity);GO:0007165(signal transduction);GO:0005576(extracellular region);GO:0004888(transmembrane signaling receptor activity);GO:0007166(cell surface receptor signaling pathway);GO:0005615(extracellular space);GO:0005925(focal adhesion);GO:0005515(protein binding);GO:0070062(extracellular exosome);GO:0005887(integral component of plasma membrane);GO:0043312(neutrophil degranulation);GO:0006954(inflammatory response);GO:0006955(immune response);GO:0007267(cell-cell signaling);GO:0030667(secretory granule membrane);GO:0006928(movement of cell or subcellular component)","NA","NA","NA","adhesion G protein-coupled receptor E5 [Source:HGNC Symbol;Acc:HGNC:1711]",{"v":12.161243,"d":"12.16"},{"v":112.028732,"d":"112.03"},{"v":0.108554678633692,"d":"0.11"},{"v":-3.20350618840767,"d":"-3.20"},{"v":9.1036567764026e-06,"d":"0.00"},{"v":0.000370227736275371,"d":"0.00"},"down","yes"]
[174641,0,"chr7","+",66628767,66644015,"ENST00000639828",4,5951,"MSTRG.13666","KCTD7","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005829(cytosol);GO:0051260(protein homooligomerization);GO:0005886(plasma membrane);GO:0043687(post-translational protein modification)","NA","NA","NA","potassium channel tetramerization domain containing 7 [Source:HGNC Symbol;Acc:HGNC:21957]",{"v":0.250489,"d":"0.25"},{"v":2.40151,"d":"2.40"},{"v":0.104304791568638,"d":"0.10"},{"v":-3.26112266077341,"d":"-3.26"},{"v":9.14330391164938E-6,"d":"0.00"},{"v":0.000371084334365477,"d":"0.00"},"down","yes"]
[165926,0,"chr6","+",41546426,41602384,"ENST00000373063",17,5910,"ENSG00000137166","FOXP4","GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0043565(sequence-specific DNA binding);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0005515(protein binding);GO:0000981(RNA polymerase II transcription factor activity, sequence-specific DNA binding);GO:0009653(anatomical structure morphogenesis);GO:0030154(cell differentiation)","NA","NA","NA","forkhead box P4 [Source:HGNC Symbol;Acc:HGNC:20842]",{"v":1.131074,"d":"1.13"},{"v":0.123384,"d":"0.12"},{"v":9.16710432470985,"d":"9.17"},{"v":3.19646609193251,"d":"3.20"},{"v":9.23753389108682e-06,"d":"0.00"},{"v":0.000374148228675906,"d":"0.00"},"up","yes"]
[131911,0,"chr22","-",42583721,42614931,"ENST00000348657",8,3323,"MSTRG.10545","POLDIP3","GO:0005622(intracellular);GO:0003723(RNA binding);GO:0006406(mRNA export from nucleus);GO:0003676(nucleic acid binding);GO:0006810(transport);GO:0051028(mRNA transport);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016607(nuclear speck);GO:0005515(protein binding);GO:0000932(P-body);GO:0045727(positive regulation of translation);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0006417(regulation of translation);GO:0006369(termination of RNA polymerase II transcription);GO:0006405(RNA export from nucleus);GO:0031124(mRNA 3'-end processing);GO:0035145(exon-exon junction complex);GO:0000346(transcription export complex);GO:0016973(poly(A)+ mRNA export from nucleus)","NA","NA","NA","DNA polymerase delta interacting protein 3 [Source:HGNC Symbol;Acc:HGNC:23782]",{"v":0.348364,"d":"0.35"},{"v":3.402651,"d":"3.40"},{"v":0.102380173576426,"d":"0.10"},{"v":-3.28799173748297,"d":"-3.29"},{"v":9.33719474822849e-06,"d":"0.00"},{"v":0.000376776540294094,"d":"0.00"},"down","yes"]
[187250,"j","chr8","-",129841697,130016543,"MSTRG.14574.12",12,1613,"MSTRG.14574","FAM49B","NA","NA","NA","NA","NA",{"v":3.209725,"d":"3.21"},{"v":29.811943,"d":"29.81"},{"v":0.107665743222439,"d":"0.11"},{"v":-3.2153688045666,"d":"-3.22"},{"v":9.35506195238606e-06,"d":"0.00"},{"v":0.000376776540294094,"d":"0.00"},"down","yes"]
[70192,0,"chr16","-",18781295,18790334,"ENST00000322989",5,2203,"MSTRG.5711","RPS15A","GO:0003723(RNA binding);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0006412(translation);GO:0030529(intracellular ribonucleoprotein complex);GO:0003735(structural constituent of ribosome);GO:0005840(ribosome);GO:0022627(cytosolic small ribosomal subunit);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0009615(response to virus);GO:0031012(extracellular matrix);GO:0005739(mitochondrion);GO:0005515(protein binding);GO:0008284(positive regulation of cell proliferation);GO:0006413(translational initiation);GO:0006364(rRNA processing);GO:0045787(positive regulation of cell cycle);GO:0000184(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay);GO:0019083(viral transcription);GO:0006614(SRP-dependent cotranslational protein targeting to membrane)","03010(Ribosome)","K02957","NA","ribosomal protein S15a [Source:HGNC Symbol;Acc:HGNC:10389]",{"v":6.928237,"d":"6.93"},{"v":63.684681,"d":"63.68"},{"v":0.108789694652,"d":"0.11"},{"v":-3.20038619435251,"d":"-3.20"},{"v":9.37728010476952e-06,"d":"0.00"},{"v":0.000376776540294094,"d":"0.00"},"down","yes"]
[15574,0,"chr1","+",207752057,207795513,"ENST00000367041",12,3281,"MSTRG.1363","CD46","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0043086(negative regulation of catalytic activity);GO:0031410(cytoplasmic vesicle);GO:0009986(cell surface);GO:0002376(immune system process);GO:0045087(innate immune response);GO:0005925(focal adhesion);GO:0002250(adaptive immune response);GO:0030449(regulation of complement activation);GO:0046718(viral entry into host cell);GO:0070062(extracellular exosome);GO:0010628(positive regulation of gene expression);GO:0042102(positive regulation of T cell proliferation);GO:0007338(single fertilization);GO:0016032(viral process);GO:0005887(integral component of plasma membrane);GO:0002456(T cell mediated immunity);GO:0010629(negative regulation of gene expression);GO:0071636(positive regulation of transforming growth factor beta production);GO:0006958(complement activation, classical pathway);GO:0004872(receptor activity);GO:0045296(cadherin binding);GO:0001618(virus receptor activity);GO:0032733(positive regulation of interleukin-10 production);GO:0008593(regulation of Notch signaling pathway);GO:0032613(interleukin-10 production);GO:0035581(sequestering of extracellular ligand from receptor);GO:0043382(positive regulation of memory T cell differentiation);GO:0045591(positive regulation of regulatory T cell differentiation);GO:0002079(inner acrosomal membrane);GO:0001848(complement binding);GO:0004175(endopeptidase activity);GO:0004857(enzyme inhibitor activity);GO:0006508(proteolysis);GO:0045916(negative regulation of complement activation);GO:0001669(acrosomal vesicle);GO:0005737(cytoplasm);GO:0005794(Golgi apparatus);GO:0016323(basolateral plasma membrane)","04610(Complement and coagulation cascades);05162(Measles)","K04007","NA","CD46 molecule [Source:HGNC Symbol;Acc:HGNC:6953]",{"v":0.384281,"d":"0.38"},{"v":3.706776,"d":"3.71"},{"v":0.103669873766313,"d":"0.10"},{"v":-3.26993138378781,"d":"-3.27"},{"v":9.3779016689786e-06,"d":"0.00"},{"v":0.000376776540294094,"d":"0.00"},"down","yes"]
[198465,0,"chrX","-",77506905,77596875,"ENST00000623706",8,7245,"MSTRG.15376","ATRX","GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0005654(nucleoplasm);GO:0016787(hydrolase activity);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0016569(covalent chromatin modification);GO:0004386(helicase activity);GO:0032508(DNA duplex unwinding);GO:0003677(DNA binding);GO:0006334(nucleosome assembly);GO:0005694(chromosome);GO:0005515(protein binding);GO:0006281(DNA repair);GO:0006974(cellular response to DNA damage stimulus);GO:0016604(nuclear body);GO:0000781(chromosome, telomeric region);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0003682(chromatin binding);GO:0042393(histone binding);GO:0000212(meiotic spindle organization);GO:0007283(spermatogenesis);GO:0010571(positive regulation of nuclear cell cycle DNA replication);GO:0030330(DNA damage response, signal transduction by p53 class mediator);GO:0030900(forebrain development);GO:0031297(replication fork processing);GO:0032206(positive regulation of telomere maintenance);GO:0035128(post-embryonic forelimb morphogenesis);GO:0035264(multicellular organism growth);GO:0060009(Sertoli cell development);GO:0070192(chromosome organization involved in meiotic cell cycle);GO:0070198(protein localization to chromosome, telomeric region);GO:0072520(seminiferous tubule development);GO:0072711(cellular response to hydroxyurea);GO:1901581(negative regulation of telomeric RNA transcription from RNA pol II promoter);GO:0000228(nuclear chromosome);GO:0000780(condensed nuclear chromosome, centromeric region);GO:0000784(nuclear chromosome, telomeric region);GO:0000792(heterochromatin);GO:0005721(pericentric heterochromatin);GO:0016605(PML body);GO:0031618(nuclear pericentric heterochromatin);GO:0031933(telomeric heterochromatin);GO:0006338(chromatin remodeling);GO:0035064(methylated histone binding);GO:0006336(DNA replication-independent nucleosome assembly);GO:0006310(DNA recombination);GO:0003678(DNA helicase activity);GO:1904908(negative regulation of maintenance of mitotic sister chromatid cohesion, telomeric);GO:0006306(DNA methylation);GO:0070087(chromo shadow domain binding);GO:0005720(nuclear heterochromatin);GO:0015616(DNA translocase activity);GO:1900112(regulation of histone H3-K9 trimethylation);GO:1901582(positive regulation of telomeric RNA transcription from RNA pol II promoter);GO:0070603(SWI/SNF superfamily-type complex);GO:1990707(nuclear subtelomeric heterochromatin)","NA","NA","NA","ATRX, chromatin remodeler [Source:HGNC Symbol;Acc:HGNC:886]",{"v":1.152711,"d":"1.15"},{"v":0.127233,"d":"0.13"},{"v":9.05984296526844,"d":"9.06"},{"v":3.17948604417969,"d":"3.18"},{"v":9.48702741811921e-06,"d":"0.00"},{"v":0.000380395509006033,"d":"0.00"},"up","yes"]
[59509,0,"chr14","-",105741338,105743071,"ENST00000390549",4,1128,"MSTRG.4749","IGHG1","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0006508(proteolysis);GO:0005615(extracellular space);GO:0002376(immune system process);GO:0003823(antigen binding);GO:0002250(adaptive immune response);GO:0004252(serine-type endopeptidase activity);GO:0006956(complement activation);GO:0006958(complement activation, classical pathway);GO:0030449(regulation of complement activation);GO:0038096(Fc-gamma receptor signaling pathway involved in phagocytosis);GO:0034987(immunoglobulin receptor binding);GO:0006910(phagocytosis, recognition);GO:0006911(phagocytosis, engulfment);GO:0042742(defense response to bacterium);GO:0045087(innate immune response);GO:0050853(B cell receptor signaling pathway);GO:0050871(positive regulation of B cell activation);GO:0009897(external side of plasma membrane);GO:0042571(immunoglobulin complex, circulating);GO:0070062(extracellular exosome);GO:0072562(blood microparticle)","NA","NA","NA","immunoglobulin heavy constant gamma 1 (G1m marker) [Source:HGNC Symbol;Acc:HGNC:5525]",{"v":73.051865,"d":"73.05"},{"v":8.585016,"d":"8.59"},{"v":8.50922875391263,"d":"8.51"},{"v":3.08902837711354,"d":"3.09"},{"v":9.5329061778313e-06,"d":"0.00"},{"v":3.80610709546956E-4,"d":"0.00"},"up","yes"]
[71871,0,"chr16","-",30352847,30354934,"ENST00000569466",6,1417,"MSTRG.5831","CD2BP2","GO:0005634(nucleus);GO:0006397(mRNA processing);GO:0008380(RNA splicing);GO:0005737(cytoplasm);GO:0016607(nuclear speck);GO:0005829(cytosol);GO:0001650(fibrillar center);GO:0005515(protein binding);GO:0005654(nucleoplasm);GO:0010923(negative regulation of phosphatase activity);GO:0000398(mRNA splicing, via spliceosome);GO:0043021(ribonucleoprotein complex binding);GO:0000244(spliceosomal tri-snRNP complex assembly);GO:0005682(U5 snRNP)","NA","NA","NA","CD2 cytoplasmic tail binding protein 2 [Source:HGNC Symbol;Acc:HGNC:1656]",{"v":4.62666,"d":"4.63"},{"v":0.504887,"d":"0.50"},{"v":9.16375347354953,"d":"9.16"},{"v":3.19593864728602,"d":"3.20"},{"v":9.53446452516756e-06,"d":"0.00"},{"v":3.80610709546956E-4,"d":"0.00"},"up","yes"]
[159186,0,"chr5","-",140632344,140633651,"ENST00000498971",3,882,"MSTRG.12388","CD14","GO:0016020(membrane);GO:0005794(Golgi apparatus);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0005615(extracellular space);GO:0031225(anchored component of membrane);GO:0045121(membrane raft);GO:0002376(immune system process);GO:0045087(innate immune response);GO:0006954(inflammatory response);GO:0070062(extracellular exosome);GO:0071222(cellular response to lipopolysaccharide);GO:0010008(endosome membrane);GO:0043312(neutrophil degranulation);GO:0006915(apoptotic process);GO:0002224(toll-like receptor signaling pathway);GO:0002755(MyD88-dependent toll-like receptor signaling pathway);GO:0002756(MyD88-independent toll-like receptor signaling pathway);GO:0007249(I-kappaB kinase/NF-kappaB signaling);GO:0034128(negative regulation of MyD88-independent toll-like receptor signaling pathway);GO:0034142(toll-like receptor 4 signaling pathway);GO:0035666(TRIF-dependent toll-like receptor signaling pathway);GO:0070266(necroptotic process);GO:0097190(apoptotic signaling pathway);GO:0046696(lipopolysaccharide receptor complex);GO:0007166(cell surface receptor signaling pathway);GO:0030667(secretory granule membrane);GO:0038123(toll-like receptor TLR1:TLR2 signaling pathway);GO:0038124(toll-like receptor TLR6:TLR2 signaling pathway);GO:0071223(cellular response to lipoteichoic acid);GO:0071726(cellular response to diacyl bacterial lipopeptide);GO:0071727(cellular response to triacyl bacterial lipopeptide);GO:0032760(positive regulation of tumor necrosis factor production);GO:0032729(positive regulation of interferon-gamma production);GO:0031362(anchored component of external side of plasma membrane);GO:0001530(lipopolysaccharide binding);GO:0001847(opsonin receptor activity);GO:0016019(peptidoglycan receptor activity);GO:0070891(lipoteichoic acid binding);GO:0071723(lipopeptide binding);GO:0002237(response to molecule of bacterial origin);GO:0006898(receptor-mediated endocytosis);GO:0006909(phagocytosis);GO:0009408(response to heat);GO:0009617(response to bacterium);GO:0031663(lipopolysaccharide-mediated signaling pathway);GO:0032026(response to magnesium ion);GO:0032481(positive regulation of type I interferon production);GO:0032496(response to lipopolysaccharide);GO:0034612(response to tumor necrosis factor);GO:0045471(response to ethanol);GO:0045807(positive regulation of endocytosis);GO:0050715(positive regulation of cytokine secretion);GO:0051602(response to electrical stimulus);GO:0071219(cellular response to molecule of bacterial origin);GO:1901224(positive regulation of NIK/NF-kappaB signaling);GO:2000484(positive regulation of interleukin-8 secretion);GO:0009897(external side of plasma membrane);GO:0009986(cell surface)","04010(MAPK signaling pathway);04064(NF-kappa B signaling pathway);04145(Phagosome);04810(Regulation of actin cytoskeleton);04640(Hematopoietic cell lineage);04620(Toll-like receptor signaling pathway);05202(Transcriptional misregulation in cancers);05221(Acute myeloid leukemia);05130(Pathogenic Escherichia coli infection);05132(Salmonella infection);05133(Pertussis);05134(Legionellosis);05152(Tuberculosis);05146(Amoebiasis)","NA","NA","CD14 molecule [Source:HGNC Symbol;Acc:HGNC:1628]",{"v":0.897052,"d":"0.90"},{"v":8.843861,"d":"8.84"},{"v":0.101432168596951,"d":"0.10"},{"v":-3.30141282799706,"d":"-3.30"},{"v":9.55782646871701e-06,"d":"0.00"},{"v":3.80610709546956E-4,"d":"0.00"},"down","yes"]
[4583,0,"chr1","-",39565106,39575781,"ENST00000470443",8,1212,"MSTRG.440","PABPC4","GO:0003723(RNA binding);GO:0003676(nucleic acid binding);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0030529(intracellular ribonucleoprotein complex);GO:0005515(protein binding);GO:0007596(blood coagulation);GO:0005634(nucleus);GO:0006412(translation);GO:0006401(RNA catabolic process);GO:0006396(RNA processing);GO:0008143(poly(A) binding);GO:0008266(poly(U) RNA binding);GO:0010494(cytoplasmic stress granule)","03013(RNA transport);03015(mRNA surveillance pathway);03018(RNA degradation)","NA","NA","poly(A) binding protein cytoplasmic 4 [Source:HGNC Symbol;Acc:HGNC:8557]",{"v":15.135888,"d":"15.14"},{"v":1.740606,"d":"1.74"},{"v":8.69575768439268,"d":"8.70"},{"v":3.12031173884777,"d":"3.12"},{"v":9.56863863143889e-06,"d":"0.00"},{"v":3.80610709546956E-4,"d":"0.00"},"up","yes"]
[1873,0,"chr1","+",15526813,15571731,"ENST00000616884",14,5882,"ENSG00000116138","DNAJC16","GO:0005623(cell);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0045454(cell redox homeostasis);GO:0005829(cytosol)","NA","NA","NA","DnaJ heat shock protein family (Hsp40) member C16 [Source:HGNC Symbol;Acc:HGNC:29157]",{"v":1.557286,"d":"1.56"},{"v":0.173092,"d":"0.17"},{"v":8.99686871721397,"d":"9.00"},{"v":3.16942297119876,"d":"3.17"},{"v":9.62838286441852e-06,"d":"0.00"},{"v":3.82225743611748E-4,"d":"0.00"},"up","yes"]
[155888,0,"chr5","+",75337232,75361423,"ENST00000343975",19,3681,"MSTRG.12120","HMGCR","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016491(oxidoreductase activity);GO:0050661(NADP binding);GO:0055114(oxidation-reduction process);GO:0006629(lipid metabolic process);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0006694(steroid biosynthetic process);GO:0008202(steroid metabolic process);GO:0008299(isoprenoid biosynthetic process);GO:0016126(sterol biosynthetic process);GO:0016616(oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor);GO:0005515(protein binding);GO:0008203(cholesterol metabolic process);GO:0004420(hydroxymethylglutaryl-CoA reductase (NADPH) activity);GO:0050662(coenzyme binding);GO:0015936(coenzyme A metabolic process);GO:0005778(peroxisomal membrane);GO:0006695(cholesterol biosynthetic process);GO:0045540(regulation of cholesterol biosynthetic process);GO:0019216(regulation of lipid metabolic process);GO:0051262(protein tetramerization);GO:0070402(NADPH binding);GO:0042282(hydroxymethylglutaryl-CoA reductase activity);GO:0042803(protein homodimerization activity);GO:0051721(protein phosphatase 2A binding);GO:0006743(ubiquinone metabolic process);GO:0007568(aging);GO:0007584(response to nutrient);GO:0008284(positive regulation of cell proliferation);GO:0008542(visual learning);GO:0010664(negative regulation of striated muscle cell apoptotic process);GO:0010666(positive regulation of cardiac muscle cell apoptotic process);GO:0032874(positive regulation of stress-activated MAPK cascade);GO:0043066(negative regulation of apoptotic process);GO:0043407(negative regulation of MAP kinase activity);GO:0045445(myoblast differentiation);GO:0045471(response to ethanol);GO:0048643(positive regulation of skeletal muscle tissue development);GO:0048661(positive regulation of smooth muscle cell proliferation);GO:0061045(negative regulation of wound healing);GO:0061179(negative regulation of insulin secretion involved in cellular response to glucose stimulus);GO:0070374(positive regulation of ERK1 and ERK2 cascade);GO:0097756(negative regulation of blood vessel diameter);GO:0043231(intracellular membrane-bounded organelle)","00900(Terpenoid backbone biosynthesis);04152(AMPK signaling pathway);04976(Bile secretion)","K00021","EC:1.1.1.34","3-hydroxy-3-methylglutaryl-CoA reductase [Source:HGNC Symbol;Acc:HGNC:5006]",{"v":0.680699,"d":"0.68"},{"v":6.354859,"d":"6.35"},{"v":0.107114729060078,"d":"0.11"},{"v":-3.22277122001972,"d":"-3.22"},{"v":9.71285144552838e-06,"d":"0.00"},{"v":0.000384813923937124,"d":"0.00"},"down","yes"]
[43628,0,"chr12","+",57755098,57760407,"ENST00000266643",4,2982,"MSTRG.3504","MARCH9","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0016740(transferase activity);GO:0016567(protein ubiquitination);GO:0005794(Golgi apparatus);GO:0005765(lysosomal membrane);GO:0000139(Golgi membrane);GO:0005764(lysosome);GO:0005802(trans-Golgi network);GO:0005795(Golgi stack)","NA","NA","NA","membrane associated ring-CH-type finger 9 [Source:HGNC Symbol;Acc:HGNC:25139]",{"v":0.360537,"d":"0.36"},{"v":3.478762,"d":"3.48"},{"v":0.103639455645428,"d":"0.10"},{"v":-3.27035475183009,"d":"-3.27"},{"v":9.74731358075653e-06,"d":"0.00"},{"v":3.85414569466428E-4,"d":"0.00"},"down","yes"]
[95659,0,"chr19","+",7395113,7472477,"ENST00000319670",21,5212,"MSTRG.7748","ARHGEF18","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0005089(Rho guanyl-nucleotide exchange factor activity);GO:0035023(regulation of Rho protein signal transduction);GO:0043547(positive regulation of GTPase activity);GO:0005856(cytoskeleton);GO:0005085(guanyl-nucleotide exchange factor activity);GO:0070062(extracellular exosome);GO:0051056(regulation of small GTPase mediated signal transduction);GO:0016324(apical plasma membrane);GO:0030054(cell junction);GO:0043065(positive regulation of apoptotic process);GO:0007179(transforming growth factor beta receptor signaling pathway);GO:0030036(actin cytoskeleton organization);GO:0045177(apical part of cell);GO:0007264(small GTPase mediated signal transduction);GO:0008360(regulation of cell shape)","04530(Tight junction)","K21066","NA","Rho/Rac guanine nucleotide exchange factor 18 [Source:HGNC Symbol;Acc:HGNC:17090]",{"v":2.809004,"d":"2.81"},{"v":0.320733,"d":"0.32"},{"v":8.758076032089,"d":"8.76"},{"v":3.13061397441281,"d":"3.13"},{"v":9.85131633700466e-06,"d":"0.00"},{"v":0.000388501875132063,"d":"0.00"},"up","yes"]
[79798,0,"chr17","-",16031404,16194613,"ENST00000395851",45,7950,"MSTRG.6470","NCOR1","GO:0005634(nucleus);GO:0016020(membrane);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0016569(covalent chromatin modification);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0003714(transcription corepressor activity);GO:0000118(histone deacetylase complex);GO:0005876(spindle microtubule);GO:0046329(negative regulation of JNK cascade);GO:0000790(nuclear chromatin);GO:0006366(transcription from RNA polymerase II promoter);GO:0007623(circadian rhythm);GO:0044212(transcription regulatory region DNA binding);GO:0001102(RNA polymerase II activating transcription factor binding);GO:0042826(histone deacetylase binding);GO:0019216(regulation of lipid metabolic process);GO:0051225(spindle assembly);GO:0017053(transcriptional repressor complex);GO:0035257(nuclear hormone receptor binding);GO:0016580(Sin3 complex);GO:0016922(ligand-dependent nuclear receptor binding);GO:0046966(thyroid hormone receptor binding);GO:0072362(regulation of glycolytic process by negative regulation of transcription from RNA polymerase II promoter);GO:0072368(regulation of lipid transport by negative regulation of transcription from RNA polymerase II promoter);GO:1903799(negative regulation of production of miRNAs involved in gene silencing by miRNA);GO:2000191(regulation of fatty acid transport)","04919(Thyroid hormone signaling pathway);05202(Transcriptional misregulation in cancers);01522(Endocrine resistance)","K04650","NA","nuclear receptor corepressor 1 [Source:HGNC Symbol;Acc:HGNC:7672]",{"v":1.723198,"d":"1.72"},{"v":0.197334,"d":"0.20"},{"v":8.73239279597028,"d":"8.73"},{"v":3.12637702634944,"d":"3.13"},{"v":9.86430542327504e-06,"d":"0.00"},{"v":0.000388501875132063,"d":"0.00"},"up","yes"]
[177641,0,"chr7","-",107207848,107564261,"ENST00000393603",21,5418,"MSTRG.13904","COG5","GO:0006810(transport);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0015031(protein transport);GO:0005794(Golgi apparatus);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0005515(protein binding);GO:0000139(Golgi membrane);GO:0017119(Golgi transport complex);GO:0006891(intra-Golgi vesicle-mediated transport);GO:0003674(molecular_function);GO:0032588(trans-Golgi network membrane);GO:0006888(ER to Golgi vesicle-mediated transport)","NA","NA","NA","component of oligomeric golgi complex 5 [Source:HGNC Symbol;Acc:HGNC:14857]",{"v":2.909065,"d":"2.91"},{"v":0.333186,"d":"0.33"},{"v":8.73105412592366,"d":"8.73"},{"v":3.12615584519888,"d":"3.13"},{"v":9.99217136042545e-06,"d":"0.00"},{"v":0.000392763145127905,"d":"0.00"},"up","yes"]
[88220,0,"chr17","-",75845709,75855322,"ENST00000585462",8,1895,"MSTRG.7226","WBP2","GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0001105(RNA polymerase II transcription coactivator activity);GO:0045815(positive regulation of gene expression, epigenetic);GO:0071391(cellular response to estrogen stimulus);GO:0000790(nuclear chromatin);GO:0031490(chromatin DNA binding);GO:0005515(protein binding);GO:0045184(establishment of protein localization);GO:0000979(RNA polymerase II core promoter sequence-specific DNA binding);GO:0071442(positive regulation of histone H3-K14 acetylation)","NA","NA","NA","WW domain binding protein 2 [Source:HGNC Symbol;Acc:HGNC:12738]",{"v":1.648878,"d":"1.65"},{"v":15.306525,"d":"15.31"},{"v":0.107723862862407,"d":"0.11"},{"v":-3.21459022550776,"d":"-3.21"},{"v":1.00142823569043e-05,"d":"0.00"},{"v":0.000392858919651603,"d":"0.00"},"down","yes"]
[167957,0,"chr6","-",99401461,99425308,"ENST00000478777",11,2422,"MSTRG.13165","PNISR","GO:0003723(RNA binding);GO:0005634(nucleus);GO:0016607(nuclear speck);GO:0005829(cytosol)","NA","NA","NA","PNN interacting serine and arginine rich protein [Source:HGNC Symbol;Acc:HGNC:21222]",{"v":1.592748,"d":"1.59"},{"v":14.733162,"d":"14.73"},{"v":0.108106325037355,"d":"0.11"},{"v":-3.20947716077802,"d":"-3.21"},{"v":1.00631616757466e-05,"d":"0.00"},{"v":0.000394002377139821,"d":"0.00"},"down","yes"]
[97797,0,"chr19","-",15421523,15433290,"ENST00000599910",9,4609,"ENSG00000011451","WIZ","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0005654(nucleoplasm);GO:0030496(midbody);GO:0005515(protein binding);GO:0070062(extracellular exosome);GO:0050821(protein stabilization);GO:0010571(positive regulation of nuclear cell cycle DNA replication);GO:0070208(protein heterotrimerization);GO:0070984(SET domain binding)","NA","NA","NA","widely interspaced zinc finger motifs [Source:HGNC Symbol;Acc:HGNC:30917]",{"v":0.234134,"d":"0.23"},{"v":2.241403,"d":"2.24"},{"v":0.104458680567484,"d":"0.10"},{"v":-3.25899570883662,"d":"-3.26"},{"v":1.0131368621759E-5,"d":"0.00"},{"v":0.000395896611818557,"d":"0.00"},"down","yes"]
[131254,0,"chr22","-",38290692,38317408,"ENST00000396832",11,2791,"ENSG00000213923","CSNK1E","GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0005515(protein binding);GO:0048511(rhythmic process);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0008360(regulation of cell shape);GO:0000086(G2/M transition of mitotic cell cycle);GO:0010389(regulation of G2/M transition of mitotic cell cycle);GO:0097711(ciliary basal body docking);GO:0007165(signal transduction);GO:0032922(circadian regulation of gene expression);GO:0006364(rRNA processing);GO:1903827(regulation of cellular protein localization);GO:0016055(Wnt signaling pathway);GO:0042752(regulation of circadian rhythm);GO:0006281(DNA repair);GO:0006897(endocytosis);GO:0032436(positive regulation of proteasomal ubiquitin-dependent protein catabolic process);GO:0018105(peptidyl-serine phosphorylation);GO:0032091(negative regulation of protein binding);GO:1905426(positive regulation of Wnt-mediated midbrain dopaminergic neuron differentiation);GO:2000052(positive regulation of non-canonical Wnt signaling pathway);GO:0048512(circadian behavior);GO:1902004(positive regulation of amyloid-beta formation);GO:1990090(cellular response to nerve growth factor stimulus);GO:0030426(growth cone);GO:0043005(neuron projection);GO:0043025(neuronal cell body)","04310(Wnt signaling pathway);04340(Hedgehog signaling pathway);04390(Hippo signaling pathway);04392(Hippo signaling pathway - multiple species);04068(FoxO signaling pathway);04710(Circadian rhythm)","K08960","EC:2.7.11.1","casein kinase 1 epsilon [Source:HGNC Symbol;Acc:HGNC:2453]",{"v":2.959779,"d":"2.96"},{"v":0.328117,"d":"0.33"},{"v":9.0204987854942,"d":"9.02"},{"v":3.17320720903095,"d":"3.17"},{"v":1.0287863968502e-05,"d":"0.00"},{"v":0.000401226694771578,"d":"0.00"},"up","yes"]
[72711,0,"chr16","+",47461295,47699745,"ENST00000566044",32,3829,"ENSG00000102893","PHKB","GO:0003824(catalytic activity);GO:0005516(calmodulin binding);GO:0005977(glycogen metabolic process);GO:0016020(membrane);GO:0006468(protein phosphorylation);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0005975(carbohydrate metabolic process);GO:0005829(cytosol);GO:0006091(generation of precursor metabolites and energy);GO:0005980(glycogen catabolic process);GO:0005964(phosphorylase kinase complex);GO:0004689(phosphorylase kinase activity)","04020(Calcium signaling pathway);04910(Insulin signaling pathway);04922(Glucagon signaling pathway)","K07190","NA","phosphorylase kinase regulatory subunit beta [Source:HGNC Symbol;Acc:HGNC:8927]",{"v":0.300846,"d":"0.30"},{"v":2.888566,"d":"2.89"},{"v":0.10415064083701,"d":"0.10"},{"v":-3.26325637860498,"d":"-3.26"},{"v":1.03255449046989e-05,"d":"0.00"},{"v":0.000401911268337285,"d":"0.00"},"down","yes"]
[129157,"j","chr22","+",22409751,22906779,"MSTRG.10249.1",5,895,"MSTRG.10249","IGLV1-40","NA","NA","NA","NA","NA",{"v":1.151824,"d":"1.15"},{"v":11.122431,"d":"11.12"},{"v":0.103558655477386,"d":"0.10"},{"v":-3.27147995521166,"d":"-3.27"},{"v":1.05254149780014e-05,"d":"0.00"},{"v":0.000408893942180413,"d":"0.00"},"down","yes"]
[83050,0,"chr17","+",40122614,40134450,"ENST00000579565",10,1401,"MSTRG.6793","MSL1","GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0016569(covalent chromatin modification);GO:0043984(histone H4-K16 acetylation);GO:0072487(MSL complex)","NA","NA","NA","male specific lethal 1 homolog [Source:HGNC Symbol;Acc:HGNC:27905]",{"v":1.263787,"d":"1.26"},{"v":11.814153,"d":"11.81"},{"v":0.10697228993056,"d":"0.11"},{"v":-3.22469096515023,"d":"-3.22"},{"v":1.08201977636036e-05,"d":"0.00"},{"v":0.000418869694175651,"d":"0.00"},"down","yes"]
[110952,0,"chr2","+",71407239,71435060,"ENST00000409407",9,4470,"MSTRG.8816","ZNF638","GO:0008380(RNA splicing);GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0043231(intracellular membrane-bounded organelle);GO:0005654(nucleoplasm);GO:0005634(nucleus);GO:0016607(nuclear speck);GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0005737(cytoplasm);GO:0003690(double-stranded DNA binding)","NA","NA","NA","zinc finger protein 638 [Source:HGNC Symbol;Acc:HGNC:17894]",{"v":0.294474,"d":"0.29"},{"v":2.792854,"d":"2.79"},{"v":0.10543837952145,"d":"0.11"},{"v":-3.24552799198503,"d":"-3.25"},{"v":1.08241567605487E-5,"d":"0.00"},{"v":0.000418869694175651,"d":"0.00"},"down","yes"]
[121360,0,"chr20","+",408053,430966,"ENST00000415942",11,2613,"MSTRG.9535","RBCK1","GO:0046872(metal ion binding);GO:0016740(transferase activity);GO:0005515(protein binding);GO:0005829(cytosol);GO:0000209(protein polyubiquitination);GO:0032088(negative regulation of NF-kappaB transcription factor activity);GO:0016032(viral process);GO:0043123(positive regulation of I-kappaB kinase/NF-kappaB signaling);GO:0043130(ubiquitin binding);GO:0051092(positive regulation of NF-kappaB transcription factor activity);GO:0007249(I-kappaB kinase/NF-kappaB signaling);GO:0004842(ubiquitin-protein transferase activity);GO:0043161(proteasome-mediated ubiquitin-dependent protein catabolic process);GO:0050852(T cell receptor signaling pathway);GO:0010803(regulation of tumor necrosis factor-mediated signaling pathway);GO:0097039(protein linear polyubiquitination);GO:0071797(LUBAC complex);GO:0042346(positive regulation of NF-kappaB import into nucleus);GO:0043065(positive regulation of apoptotic process);GO:0060546(negative regulation of necroptotic process);GO:2001238(positive regulation of extrinsic apoptotic signaling pathway)","04217(Necroptosis);04621(NOD-like receptor signaling pathway)","K10630","EC:2.3.2.27","RANBP2-type and C3HC4-type zinc finger containing 1 [Source:HGNC Symbol;Acc:HGNC:15864]",{"v":0.396141,"d":"0.40"},{"v":3.792012,"d":"3.79"},{"v":0.104467232698631,"d":"0.10"},{"v":-3.25887759886157,"d":"-3.26"},{"v":1.0957046920443E-5,"d":"0.00"},{"v":0.000423192094598465,"d":"0.00"},"down","yes"]
[183962,0,"chr8","-",56073054,56074510,"ENST00000521262",4,650,"MSTRG.14365","RPS20","GO:0003723(RNA binding);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0006412(translation);GO:0030529(intracellular ribonucleoprotein complex);GO:0005622(intracellular);GO:0003735(structural constituent of ribosome);GO:0005840(ribosome);GO:0015935(small ribosomal subunit);GO:0005515(protein binding);GO:0022627(cytosolic small ribosomal subunit);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0031012(extracellular matrix);GO:0002181(cytoplasmic translation);GO:0006413(translational initiation);GO:0006364(rRNA processing);GO:0000184(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay);GO:0019083(viral transcription);GO:0006614(SRP-dependent cotranslational protein targeting to membrane)","03010(Ribosome)","NA","NA","ribosomal protein S20 [Source:HGNC Symbol;Acc:HGNC:10405]",{"v":111.829826,"d":"111.83"},{"v":13.391663,"d":"13.39"},{"v":8.35070491245187,"d":"8.35"},{"v":3.06189798570336,"d":"3.06"},{"v":1.11020463976382E-5,"d":"0.00"},{"v":0.000427964599359149,"d":"0.00"},"up","yes"]
[13834,0,"chr1","-",175156987,175192793,"ENST00000423313",4,4564,"MSTRG.1209","KIAA0040","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005515(protein binding)","NA","NA","NA","KIAA0040 [Source:HGNC Symbol;Acc:HGNC:28950]",{"v":1.835654,"d":"1.84"},{"v":16.583899,"d":"16.58"},{"v":0.110688927857074,"d":"0.11"},{"v":-3.17541717741637,"d":"-3.18"},{"v":1.11702924879997E-5,"d":"0.00"},{"v":0.000429765704046972,"d":"0.00"},"down","yes"]
[192123,0,"chr9","-",97600083,97633575,"ENST00000341170",10,4320,"MSTRG.14863","TSTD2","GO:0005515(protein binding);GO:0003674(molecular_function);GO:0008150(biological_process);GO:0005575(cellular_component)","NA","NA","NA","thiosulfate sulfurtransferase like domain containing 2 [Source:HGNC Symbol;Acc:HGNC:30087]",{"v":0.201169,"d":"0.20"},{"v":1.942874,"d":"1.94"},{"v":0.103541969268208,"d":"0.10"},{"v":-3.27171243264928,"d":"-3.27"},{"v":1.12129703889078e-05,"d":"0.00"},{"v":0.000430578062934058,"d":"0.00"},"down","yes"]
[606,"j","chr1","-",1785286,1848029,"MSTRG.66.4",12,3047,"MSTRG.66","GNB1","NA","NA","NA","NA","NA",{"v":0.79339,"d":"0.79"},{"v":7.324605,"d":"7.32"},{"v":0.108318469050549,"d":"0.11"},{"v":-3.20664884145255,"d":"-3.21"},{"v":1.12678862953399E-5,"d":"0.00"},{"v":0.000431856340778016,"d":"0.00"},"down","yes"]
[59489,0,"chr14","-",105643068,105644790,"ENST00000390545",4,1116,"MSTRG.4749","IGHG2","GO:0016020(membrane);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0006508(proteolysis);GO:0005615(extracellular space);GO:0002376(immune system process);GO:0003823(antigen binding);GO:0002250(adaptive immune response);GO:0004252(serine-type endopeptidase activity);GO:0006956(complement activation);GO:0006958(complement activation, classical pathway);GO:0030449(regulation of complement activation);GO:0038096(Fc-gamma receptor signaling pathway involved in phagocytosis);GO:0034987(immunoglobulin receptor binding);GO:0006910(phagocytosis, recognition);GO:0006911(phagocytosis, engulfment);GO:0042742(defense response to bacterium);GO:0045087(innate immune response);GO:0050853(B cell receptor signaling pathway);GO:0050871(positive regulation of B cell activation);GO:0009897(external side of plasma membrane);GO:0042571(immunoglobulin complex, circulating);GO:0070062(extracellular exosome);GO:0072562(blood microparticle)","NA","NA","NA","immunoglobulin heavy constant gamma 2 (G2m marker) [Source:HGNC Symbol;Acc:HGNC:5526]",{"v":87.096237,"d":"87.10"},{"v":10.517994,"d":"10.52"},{"v":8.28068897928635,"d":"8.28"},{"v":3.04975080946942,"d":"3.05"},{"v":1.15712546025533E-5,"d":"0.00"},{"v":0.00044263373927928,"d":"0.00"},"up","yes"]
[167261,0,"chr6","-",73517519,73520059,"ENST00000490569",6,1802,"MSTRG.13126","EEF1A1","GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0006412(translation);GO:0005525(GTP binding);GO:0000166(nucleotide binding);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003924(GTPase activity);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0005615(extracellular space);GO:0003746(translation elongation factor activity);GO:0006414(translational elongation);GO:0000049(tRNA binding);GO:0005730(nucleolus);GO:0005576(extracellular region);GO:0070062(extracellular exosome);GO:0019901(protein kinase binding);GO:0032587(ruffle membrane);GO:0043312(neutrophil degranulation);GO:0034774(secretory granule lumen);GO:1904813(ficolin-1-rich granule lumen);GO:0030864(cortical actin cytoskeleton);GO:0071364(cellular response to epidermal growth factor stimulus);GO:0006479(protein methylation);GO:1904714(regulation of chaperone-mediated autophagy);GO:0005853(eukaryotic translation elongation factor 1 complex);GO:0043209(myelin sheath);GO:0098574(cytoplasmic side of lysosomal membrane)","03013(RNA transport);05134(Legionellosis)","NA","NA","eukaryotic translation elongation factor 1 alpha 1 [Source:HGNC Symbol;Acc:HGNC:3189]",{"v":19.403673,"d":"19.40"},{"v":173.088547,"d":"173.09"},{"v":0.112102581807449,"d":"0.11"},{"v":-3.15710859000084,"d":"-3.16"},{"v":1.18119311350855E-5,"d":"0.00"},{"v":0.000450407494866238,"d":"0.00"},"down","yes"]
[59251,0,"chr14","+",104689637,104719603,"ENST00000392634",23,4672,"MSTRG.4708","INF2","GO:0005737(cytoplasm);GO:0003779(actin binding);GO:0030036(actin cytoskeleton organization);GO:0048471(perinuclear region of cytoplasm);GO:0016043(cellular component organization);GO:0017048(Rho GTPase binding);GO:0090140(regulation of mitochondrial fission)","NA","NA","NA","inverted formin, FH2 and WH2 domain containing [Source:HGNC Symbol;Acc:HGNC:23791]",{"v":5.672372,"d":"5.67"},{"v":0.6741,"d":"0.67"},{"v":8.41473371903278,"d":"8.41"},{"v":3.07291761875556,"d":"3.07"},{"v":1.18195877058247E-5,"d":"0.00"},{"v":0.000450407494866238,"d":"0.00"},"up","yes"]
[74769,0,"chr16","+",68085658,68229259,"ENST00000346183",10,6040,"MSTRG.6049","NFATC3","GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0006351(transcription, DNA-templated);GO:0005515(protein binding);GO:0038095(Fc-epsilon receptor signaling pathway);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0006954(inflammatory response);GO:0006366(transcription from RNA polymerase II promoter);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0001077(transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:1902894(negative regulation of pri-miRNA transcription from RNA polymerase II promoter);GO:0001227(transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding);GO:0045893(positive regulation of transcription, DNA-templated)","04010(MAPK signaling pathway);04310(Wnt signaling pathway);04022(cGMP - PKG signaling pathway);04218(Cellular senescence);04660(T cell receptor signaling pathway);04658(Th1 and Th2 cell differentiation);04659(Th17 cell differentiation);04662(B cell receptor signaling pathway);04921(Oxytocin signaling pathway);04360(Axon guidance);05166(HTLV-I infection);05161(Hepatitis B);05167(Kaposi's sarcoma-associated herpesvirus infection)","K17333","NA","nuclear factor of activated T-cells 3 [Source:HGNC Symbol;Acc:HGNC:7777]",{"v":1.444775,"d":"1.44"},{"v":12.954351,"d":"12.95"},{"v":0.111528165324531,"d":"0.11"},{"v":-3.16452000050195,"d":"-3.16"},{"v":1.20615388858733e-05,"d":"0.00"},{"v":0.000458752016139271,"d":"0.00"},"down","yes"]
[57935,0,"chr14","-",92939862,93115279,"ENST00000555495",9,3035,"MSTRG.4628","ITPK1","GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0016853(isomerase activity);GO:0016740(transferase activity);GO:0000287(magnesium ion binding);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0016787(hydrolase activity);GO:0005622(intracellular);GO:0016311(dephosphorylation);GO:0047325(inositol tetrakisphosphate 1-kinase activity);GO:0052725(inositol-1,3,4-trisphosphate 6-kinase activity);GO:0052726(inositol-1,3,4-trisphosphate 5-kinase activity);GO:0021915(neural tube development);GO:0032957(inositol trisphosphate metabolic process);GO:0016324(apical plasma membrane);GO:0005829(cytosol);GO:0007165(signal transduction);GO:0043647(inositol phosphate metabolic process);GO:0003824(catalytic activity);GO:0007596(blood coagulation);GO:0052659(inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity);GO:0052825(inositol-1,3,4,5,6-pentakisphosphate 1-phosphatase activity);GO:0052830(inositol-1,3,4,6-tetrakisphosphate 6-phosphatase activity);GO:0052831(inositol-1,3,4,6-tetrakisphosphate 1-phosphatase activity);GO:0052835(inositol-3,4,6-trisphosphate 1-kinase activity)","00562(Inositol phosphate metabolism);04070(Phosphatidylinositol signaling system)","K00913","EC:2.7.1.159;EC:2.7.1.134","inositol-tetrakisphosphate 1-kinase [Source:HGNC Symbol;Acc:HGNC:6177]",{"v":2.989567,"d":"2.99"},{"v":0.343082,"d":"0.34"},{"v":8.71385557971564,"d":"8.71"},{"v":3.12331120274647,"d":"3.12"},{"v":1.24313646623258e-05,"d":"0.00"},{"v":0.000471919181705933,"d":"0.00"},"up","yes"]
[45590,0,"chr12","+",98645300,98735433,"ENST00000359972",26,7029,"MSTRG.3634","APAF1","GO:0005737(cytoplasm);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0042981(regulation of apoptotic process);GO:0005515(protein binding);GO:0006915(apoptotic process);GO:0005576(extracellular region);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0043234(protein complex);GO:0043065(positive regulation of apoptotic process);GO:0043312(neutrophil degranulation);GO:0043531(ADP binding);GO:0097190(apoptotic signaling pathway);GO:0007399(nervous system development);GO:0034774(secretory granule lumen);GO:1904813(ficolin-1-rich granule lumen);GO:0097193(intrinsic apoptotic signaling pathway);GO:0008656(cysteine-type endopeptidase activator activity involved in apoptotic process);GO:0031072(heat shock protein binding);GO:0042802(identical protein binding);GO:0001666(response to hypoxia);GO:0001843(neural tube closure);GO:0006919(activation of cysteine-type endopeptidase activity involved in apoptotic process);GO:0007275(multicellular organism development);GO:0007420(brain development);GO:0007568(aging);GO:0007584(response to nutrient);GO:0008635(activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c);GO:0010659(cardiac muscle cell apoptotic process);GO:0030154(cell differentiation);GO:0030900(forebrain development);GO:0034349(glial cell apoptotic process);GO:0051260(protein homooligomerization);GO:0051402(neuron apoptotic process);GO:0070059(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress);GO:0071560(cellular response to transforming growth factor beta stimulus);GO:0072432(response to G1 DNA damage checkpoint signaling);GO:1902510(regulation of apoptotic DNA fragmentation);GO:2001235(positive regulation of apoptotic signaling pathway);GO:0005634(nucleus);GO:0043293(apoptosome)","04210(Apoptosis);04215(Apoptosis - multiple species);04115(p53 signaling pathway);05200(Pathways in cancer);05222(Small cell lung cancer);05010(Alzheimer's disease);05012(Parkinson's disease);05014(Amyotrophic lateral sclerosis (ALS));05016(Huntington's disease);05134(Legionellosis);05152(Tuberculosis);05161(Hepatitis B);01524(Platinum drug resistance)","K02084","NA","apoptotic peptidase activating factor 1 [Source:HGNC Symbol;Acc:HGNC:576]",{"v":1.76249,"d":"1.76"},{"v":0.206777,"d":"0.21"},{"v":8.52362690241178,"d":"8.52"},{"v":3.09146744461983,"d":"3.09"},{"v":1.25155394551708E-5,"d":"0.00"},{"v":0.000474213077496871,"d":"0.00"},"up","yes"]
[132081,0,"chr22","+",44677057,44737680,"ENST00000006251",9,1767,"ENSG00000186654","PRR5","GO:0007049(cell cycle);GO:0005829(cytosol);GO:0038111(interleukin-7-mediated signaling pathway);GO:0048015(phosphatidylinositol-mediated signaling);GO:0031295(T cell costimulation);GO:0031932(TORC2 complex);GO:0038203(TORC2 signaling);GO:0001934(positive regulation of protein phosphorylation);GO:0014068(positive regulation of phosphatidylinositol 3-kinase signaling)","04150(mTOR signaling pathway)","K20411","NA","proline rich 5 [Source:HGNC Symbol;Acc:HGNC:31682]",{"v":5.017284,"d":"5.02"},{"v":0.574897,"d":"0.57"},{"v":8.72727462484584,"d":"8.73"},{"v":3.12553119576937,"d":"3.13"},{"v":1.25625681537102E-5,"d":"0.00"},{"v":0.000475093486540311,"d":"0.00"},"up","yes"]
[136992,0,"chr3","+",52246209,52250597,"ENST00000409502",9,1790,"MSTRG.10974","PPM1M","GO:0003824(catalytic activity);GO:0006470(protein dephosphorylation);GO:0004722(protein serine/threonine phosphatase activity);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0016787(hydrolase activity);GO:0004721(phosphoprotein phosphatase activity);GO:0008420(CTD phosphatase activity);GO:0030145(manganese ion binding)","NA","NA","NA","protein phosphatase, Mg2+/Mn2+ dependent 1M [Source:HGNC Symbol;Acc:HGNC:26506]",{"v":0.814835,"d":"0.81"},{"v":7.548229,"d":"7.55"},{"v":0.107950487458714,"d":"0.11"},{"v":-3.21155833691202,"d":"-3.21"},{"v":1.26098189954629E-5,"d":"0.00"},{"v":4.75146905248889E-4,"d":"0.00"},"down","yes"]
[195604,0,"chrX","+",9465008,9719743,"ENST00000217964",18,5871,"MSTRG.15163","TBL1X","GO:0005634(nucleus);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0005515(protein binding);GO:0006508(proteolysis);GO:0045893(positive regulation of transcription, DNA-templated);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0003714(transcription corepressor activity);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0005654(nucleoplasm);GO:0007605(sensory perception of sound);GO:0008022(protein C-terminus binding);GO:0000118(histone deacetylase complex);GO:0005876(spindle microtubule);GO:0019904(protein domain specific binding);GO:0008134(transcription factor binding);GO:0042393(histone binding);GO:0044212(transcription regulatory region DNA binding);GO:0043161(proteasome-mediated ubiquitin-dependent protein catabolic process);GO:0008013(beta-catenin binding);GO:0060070(canonical Wnt signaling pathway);GO:0019216(regulation of lipid metabolic process);GO:0017053(transcriptional repressor complex);GO:0016575(histone deacetylation)","04310(Wnt signaling pathway)","K04508","NA","transducin beta like 1X-linked [Source:HGNC Symbol;Acc:HGNC:11585]",{"v":0.564052,"d":"0.56"},{"v":5.089845,"d":"5.09"},{"v":0.110819091740515,"d":"0.11"},{"v":-3.17372164683379,"d":"-3.17"},{"v":1.26115715035012e-05,"d":"0.00"},{"v":4.75146905248889E-4,"d":"0.00"},"down","yes"]
[118022,0,"chr2","+",201258036,201287711,"ENST00000358485",9,2930,"MSTRG.9357","CASP8","GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0016787(hydrolase activity);GO:0042981(regulation of apoptotic process);GO:0005515(protein binding);GO:0008233(peptidase activity);GO:0008234(cysteine-type peptidase activity);GO:0006508(proteolysis);GO:0006915(apoptotic process);GO:0004197(cysteine-type endopeptidase activity);GO:0042802(identical protein binding);GO:0016032(viral process);GO:0031625(ubiquitin protein ligase binding);GO:0043123(positive regulation of I-kappaB kinase/NF-kappaB signaling);GO:0042113(B cell activation);GO:0035666(TRIF-dependent toll-like receptor signaling pathway);GO:0071260(cellular response to mechanical stimulus);GO:0097190(apoptotic signaling pathway);GO:0006919(activation of cysteine-type endopeptidase activity involved in apoptotic process);GO:0007166(cell surface receptor signaling pathway);GO:0036462(TRAIL-activated apoptotic signaling pathway);GO:0097191(extrinsic apoptotic signaling pathway);GO:0097296(activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway);GO:1902041(regulation of extrinsic apoptotic signaling pathway via death domain receptors);GO:1902042(negative regulation of extrinsic apoptotic signaling pathway via death domain receptors);GO:0005856(cytoskeleton);GO:0030101(natural killer cell activation);GO:0042110(T cell activation);GO:0097194(execution phase of apoptosis);GO:0005741(mitochondrial outer membrane);GO:0005739(mitochondrion);GO:0034612(response to tumor necrosis factor);GO:0043124(negative regulation of I-kappaB kinase/NF-kappaB signaling);GO:0010803(regulation of tumor necrosis factor-mediated signaling pathway);GO:0070423(nucleotide-binding oligomerization domain containing signaling pathway);GO:1900740(positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway);GO:0097200(cysteine-type endopeptidase activity involved in execution phase of apoptosis);GO:0031264(death-inducing signaling complex);GO:0097342(ripoptosome);GO:0071550(death-inducing signaling complex assembly);GO:0045651(positive regulation of macrophage differentiation);GO:0030225(macrophage differentiation);GO:0051603(proteolysis involved in cellular protein catabolic process);GO:0060544(regulation of necroptotic process);GO:0031265(CD95 death-inducing signaling complex);GO:0097153(cysteine-type endopeptidase activity involved in apoptotic process);GO:0045862(positive regulation of proteolysis);GO:0097202(activation of cysteine-type endopeptidase activity);GO:0035877(death effector domain binding);GO:0097110(scaffold protein binding);GO:0097199(cysteine-type endopeptidase activity involved in apoptotic signaling pathway);GO:0039650(suppression by virus of host cysteine-type endopeptidase activity involved in apoptotic process);GO:0060715(syncytiotrophoblast cell differentiation involved in labyrinthine layer development);GO:0005123(death receptor binding);GO:0005164(tumor necrosis factor receptor binding);GO:0032403(protein complex binding);GO:0009409(response to cold);GO:0032025(response to cobalt ion);GO:0032355(response to estradiol);GO:0032496(response to lipopolysaccharide);GO:0045471(response to ethanol);GO:0046677(response to antibiotic);GO:0071407(cellular response to organic cyclic compound);GO:0043005(neuron projection);GO:0043234(protein complex);GO:0044297(cell body);GO:0045121(membrane raft)","04668(TNF signaling pathway);04210(Apoptosis);04215(Apoptosis - multiple species);04217(Necroptosis);04115(p53 signaling pathway);04620(Toll-like receptor signaling pathway);04621(NOD-like receptor signaling pathway);04622(RIG-I-like receptor signaling pathway);04657(IL-17 signaling pathway);05200(Pathways in cancer);05203(Viral carcinogenesis);05010(Alzheimer's disease);05016(Huntington's disease);05416(Viral myocarditis);04932(Non-alcoholic fatty liver disease (NAFLD));05134(Legionellosis);05152(Tuberculosis);05161(Hepatitis B);05168(Herpes simplex infection);05167(Kaposi's sarcoma-associated herpesvirus infection);05165(Human papillomavirus infection);05145(Toxoplasmosis);05142(Chagas disease (American trypanosomiasis));01524(Platinum drug resistance)","K04398","EC:3.4.22.61","caspase 8 [Source:HGNC Symbol;Acc:HGNC:1509]",{"v":2.435443,"d":"2.44"},{"v":0.280258,"d":"0.28"},{"v":8.69000349677797,"d":"8.69"},{"v":3.11935675756709,"d":"3.12"},{"v":1.26377794807536e-05,"d":"0.00"},{"v":0.000475237628383593,"d":"0.00"},"up","yes"]
[20886,"j","chr10","+",69057566,69104818,"MSTRG.1749.1",4,1911,"MSTRG.1749","SRGN","NA","NA","NA","NA","NA",{"v":13.827067,"d":"13.83"},{"v":122.318222,"d":"122.32"},{"v":0.11304175922374,"d":"0.11"},{"v":-3.14507227184158,"d":"-3.15"},{"v":1.2712651689744E-5,"d":"0.00"},{"v":0.00047715456567821,"d":"0.00"},"down","yes"]
[10651,0,"chr1","-",150811961,150876609,"ENST00000505755",21,2427,"MSTRG.930","ARNT","GO:0045648(positive regulation of erythrocyte differentiation);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0046983(protein dimerization activity);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0005515(protein binding);GO:0030522(intracellular receptor signaling pathway);GO:0016604(nuclear body);GO:0005667(transcription factor complex);GO:0005654(nucleoplasm);GO:0061418(regulation of transcription from RNA polymerase II promoter in response to hypoxia);GO:0006805(xenobiotic metabolic process);GO:0046982(protein heterodimerization activity);GO:0003713(transcription coactivator activity);GO:0001938(positive regulation of endothelial cell proliferation);GO:0045893(positive regulation of transcription, DNA-templated);GO:0017162(aryl hydrocarbon receptor binding);GO:0090575(RNA polymerase II transcription factor complex);GO:0003705(transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding);GO:0043565(sequence-specific DNA binding);GO:0008134(transcription factor binding);GO:0010575(positive regulation of vascular endothelial growth factor production);GO:0045821(positive regulation of glycolytic process);GO:0030949(positive regulation of vascular endothelial growth factor receptor signaling pathway);GO:0001666(response to hypoxia);GO:0043619(regulation of transcription from RNA polymerase II promoter in response to oxidative stress);GO:0042789(mRNA transcription from RNA polymerase II promoter);GO:0000989(transcription factor activity, transcription factor binding);GO:0004874(aryl hydrocarbon receptor activity);GO:0035326(enhancer binding);GO:0001892(embryonic placenta development);GO:0030154(cell differentiation);GO:0033235(positive regulation of protein sumoylation);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0046886(positive regulation of hormone biosynthetic process)","04066(HIF-1 signaling pathway);05200(Pathways in cancer);05204(Chemical carcinogenesis);05211(Renal cell carcinoma)","K09097","NA","aryl hydrocarbon receptor nuclear translocator [Source:HGNC Symbol;Acc:HGNC:700]",{"v":10.980676,"d":"10.98"},{"v":1.320955,"d":"1.32"},{"v":8.31267984147832,"d":"8.31"},{"v":3.05531364796462,"d":"3.06"},{"v":1.2846716867673e-05,"d":"0.00"},{"v":0.000481281880701114,"d":"0.00"},"up","yes"]
[46737,0,"chr12","-",111642146,111685986,"ENST00000419234",12,4026,"MSTRG.3724","BRAP","GO:0003676(nucleic acid binding);GO:0005737(cytoplasm);GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0005829(cytosol);GO:0016740(transferase activity);GO:0016567(protein ubiquitination);GO:0031965(nuclear membrane);GO:0005515(protein binding);GO:0042802(identical protein binding);GO:0061630(ubiquitin protein ligase activity);GO:0000165(MAPK cascade);GO:0004842(ubiquitin-protein transferase activity);GO:0009968(negative regulation of signal transduction);GO:0000151(ubiquitin ligase complex);GO:0008139(nuclear localization sequence binding);GO:0007265(Ras protein signal transduction)","04014(Ras signaling pathway)","K10632","EC:2.3.2.27","BRCA1 associated protein [Source:HGNC Symbol;Acc:HGNC:1099]",{"v":0.431968,"d":"0.43"},{"v":3.964201,"d":"3.96"},{"v":0.108967229461876,"d":"0.11"},{"v":-3.19803376723603,"d":"-3.20"},{"v":1.307963075709E-5,"d":"0.00"},{"v":0.000489090013029164,"d":"0.00"},"down","yes"]
[5566,0,"chr1","-",45627306,45686630,"ENST00000355105",13,3736,"MSTRG.525","GPBP1L1","GO:0005634(nucleus);GO:0045893(positive regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding)","NA","NA","NA","GC-rich promoter binding protein 1 like 1 [Source:HGNC Symbol;Acc:HGNC:28843]",{"v":0.870639,"d":"0.87"},{"v":7.817316,"d":"7.82"},{"v":0.111373136252903,"d":"0.11"},{"v":-3.16652680537309,"d":"-3.17"},{"v":1.31619530024529e-05,"d":"0.00"},{"v":0.000491248369257904,"d":"0.00"},"down","yes"]
[8797,0,"chr1","-",109309570,109397951,"ENST00000256637",20,7028,"MSTRG.760","SORT1","GO:0048471(perinuclear region of cytoplasm);GO:0051005(negative regulation of lipoprotein lipase activity);GO:0006810(transport);GO:0005634(nucleus);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005794(Golgi apparatus);GO:0005829(cytosol);GO:0005765(lysosomal membrane);GO:0005886(plasma membrane);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005515(protein binding);GO:0007275(multicellular organism development);GO:0030154(cell differentiation);GO:0005764(lysosome);GO:0032580(Golgi cisterna membrane);GO:0005768(endosome);GO:0006897(endocytosis);GO:0010008(endosome membrane);GO:0001503(ossification);GO:0009986(cell surface);GO:0031965(nuclear membrane);GO:0016050(vesicle organization);GO:0031410(cytoplasmic vesicle);GO:0019899(enzyme binding);GO:0005769(early endosome);GO:0007186(G-protein coupled receptor signaling pathway);GO:0005905(clathrin-coated pit);GO:0008625(extrinsic apoptotic signaling pathway via death domain receptors);GO:0007218(neuropeptide signaling pathway);GO:0010468(regulation of gene expression);GO:0048406(nerve growth factor binding);GO:0046323(glucose import);GO:0032868(response to insulin);GO:0008333(endosome to lysosome transport);GO:0010465(nerve growth factor receptor activity);GO:0030379(neurotensin receptor activity, non-G-protein coupled);GO:0006895(Golgi to endosome transport);GO:0014902(myotube differentiation);GO:0032509(endosome transport via multivesicular body sorting pathway);GO:0038180(nerve growth factor signaling pathway);GO:0045599(negative regulation of fat cell differentiation);GO:0048011(neurotrophin TRK receptor signaling pathway);GO:0048227(plasma membrane to endosome transport);GO:1904037(positive regulation of epithelial cell apoptotic process);GO:0030136(clathrin-coated vesicle);GO:0030140(trans-Golgi network transport vesicle);GO:0030425(dendrite);GO:0030659(cytoplasmic vesicle membrane);GO:0043025(neuronal cell body);GO:0043231(intracellular membrane-bounded organelle)","04142(Lysosome);04979(Cholesterol metabolism);04722(Neurotrophin signaling pathway)","K12388","NA","sortilin 1 [Source:HGNC Symbol;Acc:HGNC:11186]",{"v":0.701083,"d":"0.70"},{"v":6.241079,"d":"6.24"},{"v":0.112333620516581,"d":"0.11"},{"v":-3.15413831591666,"d":"-3.15"},{"v":1.32884146825385E-5,"d":"0.00"},{"v":4.95043030561436E-4,"d":"0.00"},"down","yes"]
[59504,0,"chr14","-",105707118,105708665,"ENST00000390547",3,1112,"MSTRG.4749","IGHA1","GO:0016020(membrane);GO:0005886(plasma membrane);GO:0005576(extracellular region);GO:0006955(immune response);GO:0005615(extracellular space);GO:0002376(immune system process);GO:0003823(antigen binding);GO:0002250(adaptive immune response);GO:0006898(receptor-mediated endocytosis);GO:0050900(leukocyte migration);GO:0006910(phagocytosis, recognition);GO:0006911(phagocytosis, engulfment);GO:0006958(complement activation, classical pathway);GO:0045087(innate immune response);GO:0050853(B cell receptor signaling pathway);GO:0050871(positive regulation of B cell activation);GO:0009897(external side of plasma membrane);GO:0018298(protein-chromophore linkage);GO:0070062(extracellular exosome);GO:0001895(retina homeostasis);GO:0072562(blood microparticle);GO:0019731(antibacterial humoral response);GO:0034987(immunoglobulin receptor binding);GO:0003094(glomerular filtration);GO:0060267(positive regulation of respiratory burst);GO:0071748(monomeric IgA immunoglobulin complex);GO:0071751(secretory IgA immunoglobulin complex);GO:0071752(secretory dimeric IgA immunoglobulin complex)","NA","NA","NA","immunoglobulin heavy constant alpha 1 [Source:HGNC Symbol;Acc:HGNC:5478]",{"v":289.396942,"d":"289.40"},{"v":35.666016,"d":"35.67"},{"v":8.11408097837448,"d":"8.11"},{"v":3.02042770068522,"d":"3.02"},{"v":1.33327977414171e-05,"d":"0.00"},{"v":0.000495771518250681,"d":"0.00"},"up","yes"]
[58287,0,"chr14","+",96502558,96565428,"ENST00000392990",21,2588,"MSTRG.4656","PAPOLA","GO:0005634(nucleus);GO:0003723(RNA binding);GO:0006397(mRNA processing);GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0005654(nucleoplasm);GO:0016740(transferase activity);GO:0016779(nucleotidyltransferase activity);GO:0000287(magnesium ion binding);GO:0004652(polynucleotide adenylyltransferase activity);GO:0031123(RNA 3'-end processing);GO:0043631(RNA polyadenylation);GO:0005515(protein binding);GO:0006369(termination of RNA polymerase II transcription);GO:0031124(mRNA 3'-end processing);GO:0000398(mRNA splicing, via spliceosome);GO:0006378(mRNA polyadenylation);GO:0031440(regulation of mRNA 3'-end processing);GO:0030145(manganese ion binding)","03015(mRNA surveillance pathway)","K14376","EC:2.7.7.19","poly(A) polymerase alpha [Source:HGNC Symbol;Acc:HGNC:14981]",{"v":6.392072,"d":"6.39"},{"v":0.770237,"d":"0.77"},{"v":8.29883789015589,"d":"8.30"},{"v":3.05290932591847,"d":"3.05"},{"v":1.3770490083663E-5,"d":"0.00"},{"v":0.000511095066896993,"d":"0.00"},"up","yes"]
[46244,0,"chr12","-",108288044,108339317,"ENST00000312143",3,5283,"MSTRG.3680","CMKLR1","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0004930(G-protein coupled receptor activity);GO:0007186(G-protein coupled receptor signaling pathway);GO:0005886(plasma membrane);GO:0004871(signal transducer activity);GO:0007165(signal transduction);GO:0070098(chemokine-mediated signaling pathway);GO:0006935(chemotaxis);GO:0005515(protein binding);GO:0032088(negative regulation of NF-kappaB transcription factor activity);GO:0005887(integral component of plasma membrane);GO:0006955(immune response);GO:0004872(receptor activity);GO:0001501(skeletal system development);GO:0004950(chemokine receptor activity);GO:0045600(positive regulation of fat cell differentiation);GO:0050848(regulation of calcium-mediated signaling);GO:0032695(negative regulation of interleukin-12 production);GO:0010759(positive regulation of macrophage chemotaxis)","NA","NA","NA","chemerin chemokine-like receptor 1 [Source:HGNC Symbol;Acc:HGNC:2121]",{"v":0.259946,"d":"0.26"},{"v":2.370856,"d":"2.37"},{"v":0.109642255792844,"d":"0.11"},{"v":-3.18912417912589,"d":"-3.19"},{"v":1.38660491023552E-5,"d":"0.00"},{"v":5.13686954500611E-4,"d":"0.00"},"down","yes"]
[133513,0,"chr3","-",12836060,12841529,"ENST00000396953",3,1734,"MSTRG.10672","RPL32","GO:0003723(RNA binding);GO:0016020(membrane);GO:0006412(translation);GO:0030529(intracellular ribonucleoprotein complex);GO:0005622(intracellular);GO:0003735(structural constituent of ribosome);GO:0005840(ribosome);GO:0071549(cellular response to dexamethasone stimulus);GO:0097421(liver regeneration);GO:0022625(cytosolic large ribosomal subunit);GO:0005829(cytosol);GO:0006413(translational initiation);GO:0006364(rRNA processing);GO:0000184(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay);GO:0019083(viral transcription);GO:0006614(SRP-dependent cotranslational protein targeting to membrane)","03010(Ribosome)","K02912","NA","ribosomal protein L32 [Source:HGNC Symbol;Acc:HGNC:10336]",{"v":32.642639,"d":"32.64"},{"v":4.013477,"d":"4.01"},{"v":8.13325677461214,"d":"8.13"},{"v":3.02383316186331,"d":"3.02"},{"v":1.40221574126859E-5,"d":"0.00"},{"v":0.000518040511422402,"d":"0.00"},"up","yes"]
[123323,0,"chr20","-",35650326,35664900,"ENST00000374104",3,5213,"MSTRG.9710","RBM12","GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0005515(protein binding)","NA","NA","NA","RNA binding motif protein 12 [Source:HGNC Symbol;Acc:HGNC:9898]",{"v":3.28019,"d":"3.28"},{"v":0.394303,"d":"0.39"},{"v":8.31895775583752,"d":"8.32"},{"v":3.05640279102589,"d":"3.06"},{"v":1.40354525580689e-05,"d":"0.00"},{"v":0.000518040511422402,"d":"0.00"},"up","yes"]
[2629,0,"chr1","-",23310333,23344295,"ENST00000606561",9,1837,"MSTRG.230","HNRNPR","GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0006397(mRNA processing);GO:0008380(RNA splicing);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005654(nucleoplasm);GO:0030529(intracellular ribonucleoprotein complex);GO:0005783(endoplasmic reticulum);GO:0005515(protein binding);GO:0005681(spliceosomal complex);GO:0043231(intracellular membrane-bounded organelle);GO:0000398(mRNA splicing, via spliceosome);GO:0016070(RNA metabolic process);GO:0071013(catalytic step 2 spliceosome);GO:0003730(mRNA 3'-UTR binding);GO:0007623(circadian rhythm);GO:0043086(negative regulation of catalytic activity);GO:0061014(positive regulation of mRNA catabolic process);GO:0061157(mRNA destabilization);GO:0030425(dendrite);GO:0030426(growth cone);GO:0043679(axon terminus);GO:0019013(viral nucleocapsid)","NA","NA","NA","heterogeneous nuclear ribonucleoprotein R [Source:HGNC Symbol;Acc:HGNC:5047]",{"v":1.027339,"d":"1.03"},{"v":9.225706,"d":"9.23"},{"v":0.111356139031528,"d":"0.11"},{"v":-3.16674699921158,"d":"-3.17"},{"v":1.41130297215994E-5,"d":"0.00"},{"v":0.000519942762879884,"d":"0.00"},"down","yes"]
[1249,0,"chr1","-",8354093,8423666,"ENST00000476556",13,4598,"MSTRG.122","RERE","GO:0005634(nucleus);GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0043565(sequence-specific DNA binding);GO:0005515(protein binding);GO:0007275(multicellular organism development);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0001105(RNA polymerase II transcription coactivator activity);GO:0001106(RNA polymerase II transcription corepressor activity);GO:0003682(chromatin binding);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0006338(chromatin remodeling);GO:0021549(cerebellum development);GO:0021691(cerebellar Purkinje cell layer maturation);GO:0021930(cerebellar granule cell precursor proliferation);GO:0021942(radial glia guided migration of Purkinje cell);GO:0048755(branching morphogenesis of a nerve);GO:0048813(dendrite morphogenesis);GO:0000118(histone deacetylase complex);GO:0006607(NLS-bearing protein import into nucleus);GO:0008267(poly-glutamine tract binding)","NA","NA","NA","arginine-glutamic acid dipeptide repeats [Source:HGNC Symbol;Acc:HGNC:9965]",{"v":7.984778,"d":"7.98"},{"v":0.97973,"d":"0.98"},{"v":8.14997805517847,"d":"8.15"},{"v":3.02679617471453,"d":"3.03"},{"v":1.42777230142314E-5,"d":"0.00"},{"v":0.000525041571175273,"d":"0.00"},"up","yes"]
[20889,"j","chr10","+",69087280,69104818,"MSTRG.1749.4",4,1686,"MSTRG.1749","SRGN","NA","NA","NA","NA","NA",{"v":11.478688,"d":"11.48"},{"v":100.03344,"d":"100.03"},{"v":0.114748508098892,"d":"0.11"},{"v":-3.12345269830555,"d":"-3.12"},{"v":1.44479772510809e-05,"d":"0.00"},{"v":0.000530325753216148,"d":"0.00"},"down","yes"]
[172514,"j","chr7","-",26189927,26201243,"MSTRG.13527.1",12,3593,"MSTRG.13527","HNRNPA2B1","NA","NA","NA","NA","NA",{"v":3.029501,"d":"3.03"},{"v":26.426405,"d":"26.43"},{"v":0.114639164880732,"d":"0.11"},{"v":-3.12482808982937,"d":"-3.12"},{"v":1.45795808305923e-05,"d":"0.00"},{"v":0.000534174440413334,"d":"0.00"},"down","yes"]
[38175,"j","chr12","+",6951262,6961316,"MSTRG.3080.7",17,2079,"MSTRG.3080","PTPN6","NA","NA","NA","NA","NA",{"v":0.630619,"d":"0.63"},{"v":5.782598,"d":"5.78"},{"v":0.109054615243875,"d":"0.11"},{"v":-3.19687726806729,"d":"-3.20"},{"v":1.46164875894009e-05,"d":"0.00"},{"v":5.34545831840948E-4,"d":"0.00"},"down","yes"]
[113999,0,"chr2","+",120252805,120293665,"ENST00000420510",5,1252,"MSTRG.9074","RALB","GO:0005622(intracellular);GO:0005525(GTP binding);GO:0016020(membrane);GO:0000166(nucleotide binding);GO:0007165(signal transduction);GO:0003924(GTPase activity);GO:0005886(plasma membrane);GO:0007265(Ras protein signal transduction);GO:0051301(cell division);GO:0007049(cell cycle);GO:0006915(apoptotic process);GO:0030496(midbody);GO:0005515(protein binding);GO:0000145(exocyst);GO:0070062(extracellular exosome);GO:0001934(positive regulation of protein phosphorylation);GO:0071902(positive regulation of protein serine/threonine kinase activity);GO:0009267(cellular response to starvation);GO:0031625(ubiquitin protein ligase binding);GO:0005776(autophagosome);GO:0019003(GDP binding);GO:0032092(positive regulation of protein binding);GO:0000910(cytokinesis);GO:0032091(negative regulation of protein binding);GO:0051117(ATPase binding);GO:0071360(cellular response to exogenous dsRNA);GO:0001928(regulation of exocyst assembly);GO:0060178(regulation of exocyst localization);GO:2000786(positive regulation of autophagosome assembly)","04014(Ras signaling pathway);04015(Rap1 signaling pathway);04072(Phospholipase D signaling pathway);05200(Pathways in cancer);05210(Colorectal cancer);05212(Pancreatic cancer)","K07835","NA","RAS like proto-oncogene B [Source:HGNC Symbol;Acc:HGNC:9840]",{"v":1.422277,"d":"1.42"},{"v":12.803951,"d":"12.80"},{"v":0.111081103012656,"d":"0.11"},{"v":-3.17031468687987,"d":"-3.17"},{"v":1.47352158558389E-5,"d":"0.00"},{"v":0.000537215730818581,"d":"0.00"},"down","yes"]
[10601,0,"chr1","-",150574551,150579738,"ENST00000620947",4,3626,"MSTRG.917","MCL1","GO:0043066(negative regulation of apoptotic process);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0071806(protein transmembrane transport);GO:0005739(mitochondrion);GO:0042981(regulation of apoptotic process);GO:0005829(cytosol);GO:0005515(protein binding);GO:0006915(apoptotic process);GO:0007275(multicellular organism development);GO:0005741(mitochondrial outer membrane);GO:0030154(cell differentiation);GO:0005654(nucleoplasm);GO:0046982(protein heterodimerization activity);GO:0001709(cell fate determination);GO:0042803(protein homodimerization activity);GO:2000811(negative regulation of anoikis);GO:0008630(intrinsic apoptotic signaling pathway in response to DNA damage);GO:0010507(negative regulation of autophagy);GO:0034097(response to cytokine);GO:0019725(cellular homeostasis);GO:2001240(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand);GO:2001020(regulation of response to DNA damage stimulus);GO:0097192(extrinsic apoptotic signaling pathway in absence of ligand);GO:0097136(Bcl-2 family protein complex);GO:0015266(protein channel activity);GO:0051434(BH3 domain binding);GO:0008637(apoptotic mitochondrial changes);GO:1903378(positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway);GO:2001243(negative regulation of intrinsic apoptotic signaling pathway);GO:0005759(mitochondrial matrix)","04630(Jak-STAT signaling pathway);04151(PI3K-Akt signaling pathway);04210(Apoptosis);05206(MicroRNAs in cancer)","K02539","NA","MCL1, BCL2 family apoptosis regulator [Source:HGNC Symbol;Acc:HGNC:6943]",{"v":0.848445,"d":"0.85"},{"v":7.514528,"d":"7.51"},{"v":0.112907291050083,"d":"0.11"},{"v":-3.14678944294684,"d":"-3.15"},{"v":1.4743300304917e-05,"d":"0.00"},{"v":0.000537215730818581,"d":"0.00"},"down","yes"]
[165250,0,"chr6","-",33318559,33323016,"ENST00000414083",7,2355,"MSTRG.12946","DAXX","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0016569(covalent chromatin modification);GO:0006334(nucleosome assembly);GO:0005694(chromosome);GO:0005829(cytosol);GO:0005515(protein binding);GO:0016604(nuclear body);GO:0006915(apoptotic process);GO:0003713(transcription coactivator activity);GO:0005654(nucleoplasm);GO:0005730(nucleolus);GO:0000775(chromosome, centromeric region);GO:0003714(transcription corepressor activity);GO:0016032(viral process);GO:0031625(ubiquitin protein ligase binding);GO:0047485(protein N-terminus binding);GO:0019899(enzyme binding);GO:0042393(histone binding);GO:0008625(extrinsic apoptotic signaling pathway via death domain receptors);GO:0045892(negative regulation of transcription, DNA-templated);GO:0006338(chromatin remodeling);GO:0016605(PML body);GO:0030521(androgen receptor signaling pathway);GO:0046982(protein heterodimerization activity);GO:0005057(signal transducer activity, downstream of receptor);GO:0002039(p53 binding);GO:0050681(androgen receptor binding);GO:0034605(cellular response to heat);GO:0019901(protein kinase binding);GO:0031072(heat shock protein binding);GO:0007257(activation of JUN kinase activity);GO:0032183(SUMO binding);GO:0071276(cellular response to cadmium ion);GO:1901216(positive regulation of neuron death);GO:1903936(cellular response to sodium arsenite);GO:0071280(cellular response to copper ion);GO:0031396(regulation of protein ubiquitination);GO:0001934(positive regulation of protein phosphorylation);GO:0070603(SWI/SNF superfamily-type complex);GO:0034620(cellular response to unfolded protein);GO:0072738(cellular response to diamide);GO:0030295(protein kinase activator activity);GO:0045860(positive regulation of protein kinase activity)","04010(MAPK signaling pathway);04210(Apoptosis);05014(Amyotrophic lateral sclerosis (ALS));05168(Herpes simplex infection)","K02308","NA","death domain associated protein [Source:HGNC Symbol;Acc:HGNC:2681]",{"v":0.456773,"d":"0.46"},{"v":4.180586,"d":"4.18"},{"v":0.109260519936679,"d":"0.11"},{"v":-3.19415590138752,"d":"-3.19"},{"v":1.48839899585169E-5,"d":"0.00"},{"v":0.000541354301442015,"d":"0.00"},"down","yes"]
[41676,0,"chr12","+",51238724,51243931,"ENST00000449723",5,2098,"MSTRG.3374","DAZAP2","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016607(nuclear speck);GO:0005515(protein binding);GO:0042802(identical protein binding);GO:0050699(WW domain binding)","NA","NA","NA","DAZ associated protein 2 [Source:HGNC Symbol;Acc:HGNC:2684]",{"v":1.753106,"d":"1.75"},{"v":15.447305,"d":"15.45"},{"v":0.113489440391059,"d":"0.11"},{"v":-3.13937002648279,"d":"-3.14"},{"v":1.50564476568654E-5,"d":"0.00"},{"v":0.000546631176022341,"d":"0.00"},"down","yes"]
[169362,0,"chr6","-",134169881,134177905,"ENST00000528577",12,1850,"MSTRG.13288","SGK1","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016607(nuclear speck);GO:0016020(membrane);GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0005829(cytosol);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005739(mitochondrion);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0006915(apoptotic process);GO:0035556(intracellular signal transduction);GO:0034220(ion transmembrane transport);GO:0004712(protein serine/threonine/tyrosine kinase activity);GO:0005246(calcium channel regulator activity);GO:0015459(potassium channel regulator activity);GO:0017080(sodium channel regulator activity);GO:0017081(chloride channel regulator activity);GO:0001558(regulation of cell growth);GO:0006814(sodium ion transport);GO:0006950(response to stress);GO:0006974(cellular response to DNA damage stimulus);GO:0007616(long-term memory);GO:0008217(regulation of blood pressure);GO:0018105(peptidyl-serine phosphorylation);GO:0030334(regulation of cell migration);GO:0032411(positive regulation of transporter activity);GO:0042127(regulation of cell proliferation);GO:0042981(regulation of apoptotic process);GO:0048812(neuron projection morphogenesis);GO:0050790(regulation of catalytic activity);GO:0051090(regulation of sequence-specific DNA binding transcription factor activity);GO:0060453(regulation of gastric acid secretion);GO:0070294(renal sodium ion absorption);GO:0035091(phosphatidylinositol binding)","04068(FoxO signaling pathway);04151(PI3K-Akt signaling pathway);04150(mTOR signaling pathway);04960(Aldosterone-regulated sodium reabsorption)","K13302","EC:2.7.11.1","serum/glucocorticoid regulated kinase 1 [Source:HGNC Symbol;Acc:HGNC:10810]",{"v":0.444407,"d":"0.44"},{"v":4.141429,"d":"4.14"},{"v":0.107307646708419,"d":"0.11"},{"v":-3.22017520914482,"d":"-3.22"},{"v":1.53031483962299e-05,"d":"0.00"},{"v":0.000554579432261194,"d":"0.00"},"down","yes"]
[94669,0,"chr19","-",2511219,2702709,"ENST00000382159",5,4208,"MSTRG.7637","GNG7","GO:0016020(membrane);GO:0007186(G-protein coupled receptor signaling pathway);GO:0004871(signal transducer activity);GO:0005886(plasma membrane);GO:0007165(signal transduction);GO:0005834(heterotrimeric G-protein complex);GO:0070062(extracellular exosome);GO:0008277(regulation of G-protein coupled receptor protein signaling pathway);GO:0071377(cellular response to glucagon stimulus)","04014(Ras signaling pathway);04371(Apelin signaling pathway);04151(PI3K-Akt signaling pathway);04062(Chemokine signaling pathway);04926(Relaxin signaling pathway);04724(Glutamatergic synapse);04727(GABAergic synapse);04725(Cholinergic synapse);04728(Dopaminergic synapse);04726(Serotonergic synapse);04723(Retrograde endocannabinoid signaling);04740(Olfactory transduction);04713(Circadian entrainment);05200(Pathways in cancer);05032(Morphine addiction);05034(Alcoholism);05167(Kaposi's sarcoma-associated herpesvirus infection)","K04543","NA","G protein subunit gamma 7 [Source:HGNC Symbol;Acc:HGNC:4410]",{"v":0.371042,"d":"0.37"},{"v":3.328527,"d":"3.33"},{"v":0.111473333399429,"d":"0.11"},{"v":-3.16522946432595,"d":"-3.17"},{"v":1.54471078980384e-05,"d":"0.00"},{"v":0.000558782337876868,"d":"0.00"},"down","yes"]
[48043,0,"chr12","-",123295905,123364828,"ENST00000602398",32,4313,"MSTRG.3833","SBNO1","GO:0006355(regulation of transcription, DNA-templated);GO:0003674(molecular_function);GO:0008150(biological_process);GO:0005575(cellular_component)","NA","NA","NA","strawberry notch homolog 1 [Source:HGNC Symbol;Acc:HGNC:22973]",{"v":2.023827,"d":"2.02"},{"v":0.239218,"d":"0.24"},{"v":8.46017858187929,"d":"8.46"},{"v":3.08068811682896,"d":"3.08"},{"v":1.54984612440763e-05,"d":"0.00"},{"v":0.000559626173818653,"d":"0.00"},"up","yes"]
[23199,"j","chr10","-",103088060,103181329,"MSTRG.1950.7",20,3552,"MSTRG.1950","NT5C2","NA","NA","NA","NA","NA",{"v":0.307946,"d":"0.31"},{"v":2.813293,"d":"2.81"},{"v":0.109461047960522,"d":"0.11"},{"v":-3.19151052105857,"d":"-3.19"},{"v":1.55827576721923e-05,"d":"0.00"},{"v":0.000561654341513243,"d":"0.00"},"down","yes"]
[99816,"j","chr19","+",34428352,34471318,"MSTRG.8066.1",18,4195,"MSTRG.8066","UBA2","NA","NA","NA","NA","NA",{"v":0.180749,"d":"0.18"},{"v":1.698665,"d":"1.70"},{"v":0.106406501576238,"d":"0.11"},{"v":-3.2323417908036,"d":"-3.23"},{"v":1.56244447419946E-5,"d":"0.00"},{"v":0.000562142184879545,"d":"0.00"},"down","yes"]
[113692,0,"chr2","+",113173997,113209396,"ENST00000441564",17,11234,"MSTRG.9063","PSD4","GO:0016020(membrane);GO:0005886(plasma membrane);GO:0043547(positive regulation of GTPase activity);GO:0042995(cell projection);GO:0005543(phospholipid binding);GO:0005086(ARF guanyl-nucleotide exchange factor activity);GO:0032012(regulation of ARF protein signal transduction);GO:0005085(guanyl-nucleotide exchange factor activity);GO:0008289(lipid binding);GO:0032587(ruffle membrane)","04144(Endocytosis)","K12494","NA","pleckstrin and Sec7 domain containing 4 [Source:HGNC Symbol;Acc:HGNC:19096]",{"v":0.598385,"d":"0.60"},{"v":5.203594,"d":"5.20"},{"v":0.114994559529433,"d":"0.11"},{"v":-3.12036248698357,"d":"-3.12"},{"v":1.57440043993394E-5,"d":"0.00"},{"v":0.000564463669140138,"d":"0.00"},"down","yes"]
[119427,0,"chr2","+",219279267,219286900,"ENST00000336576",9,3176,"MSTRG.9439","DNAJB2","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005829(cytosol);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005515(protein binding);GO:0008285(negative regulation of cell proliferation);GO:0030308(negative regulation of cell growth);GO:0051082(unfolded protein binding);GO:0051087(chaperone binding);GO:0061077(chaperone-mediated protein folding);GO:0006986(response to unfolded protein);GO:0032091(negative regulation of protein binding);GO:0032781(positive regulation of ATPase activity);GO:0001671(ATPase activator activity);GO:0042026(protein refolding);GO:0090084(negative regulation of inclusion body assembly);GO:0030544(Hsp70 protein binding);GO:0031396(regulation of protein ubiquitination);GO:1903644(regulation of chaperone-mediated protein folding)","04141(Protein processing in endoplasmic reticulum)","K09508","NA","DnaJ heat shock protein family (Hsp40) member B2 [Source:HGNC Symbol;Acc:HGNC:5228]",{"v":4.660537,"d":"4.66"},{"v":0.564623,"d":"0.56"},{"v":8.25424575336109,"d":"8.25"},{"v":3.0451363922918,"d":"3.05"},{"v":1.57455059951451e-05,"d":"0.00"},{"v":0.000564463669140138,"d":"0.00"},"up","yes"]
[13854,0,"chr1","-",175945153,176206978,"ENST00000308769",19,2124,"MSTRG.1220","RFWD2","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016607(nuclear speck);GO:0046872(metal ion binding);GO:0016740(transferase activity);GO:0016567(protein ubiquitination);GO:0005515(protein binding);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0043687(post-translational protein modification);GO:0043161(proteasome-mediated ubiquitin-dependent protein catabolic process);GO:0004842(ubiquitin-protein transferase activity);GO:0061630(ubiquitin protein ligase activity);GO:0032436(positive regulation of proteasomal ubiquitin-dependent protein catabolic process);GO:0010212(response to ionizing radiation);GO:0031464(Cul4A-RING E3 ubiquitin ligase complex);GO:0000139(Golgi membrane);GO:0016020(membrane);GO:0016021(integral component of membrane)","04120(Ubiquitin mediated proteolysis);04115(p53 signaling pathway)","K10143","EC:2.3.2.27","ring finger and WD repeat domain 2 [Source:HGNC Symbol;Acc:HGNC:17440]",{"v":1.290139,"d":"1.29"},{"v":11.353247,"d":"11.35"},{"v":0.11363612541857,"d":"0.11"},{"v":-3.13750654809865,"d":"-3.14"},{"v":1.59843226750961E-5,"d":"0.00"},{"v":0.000571998127556125,"d":"0.00"},"down","yes"]
[112143,0,"chr2","-",88947301,88947957,"ENST00000496168",2,532,"MSTRG.8934","IGKV1-5","GO:0016020(membrane);GO:0005886(plasma membrane);GO:0005576(extracellular region);GO:0006508(proteolysis);GO:0006955(immune response);GO:0002376(immune system process);GO:0002377(immunoglobulin production);GO:0003823(antigen binding);GO:0002250(adaptive immune response);GO:0004252(serine-type endopeptidase activity);GO:0006898(receptor-mediated endocytosis);GO:0006956(complement activation);GO:0006958(complement activation, classical pathway);GO:0030449(regulation of complement activation);GO:0038095(Fc-epsilon receptor signaling pathway);GO:0038096(Fc-gamma receptor signaling pathway involved in phagocytosis);GO:0050776(regulation of immune response);GO:0050900(leukocyte migration);GO:0070062(extracellular exosome);GO:0072562(blood microparticle)","NA","NA","NA","immunoglobulin kappa variable 1-5 [Source:HGNC Symbol;Acc:HGNC:5741]",{"v":21.288656,"d":"21.29"},{"v":2.555483,"d":"2.56"},{"v":8.33058016821086,"d":"8.33"},{"v":3.05841697298028,"d":"3.06"},{"v":1.61106603364713e-05,"d":"0.00"},{"v":0.000575487773879534,"d":"0.00"},"up","yes"]
[55224,0,"chr14","+",55271303,55353609,"ENST00000313833",2,3464,"MSTRG.4412","FBXO34","GO:0005515(protein binding)","NA","NA","NA","F-box protein 34 [Source:HGNC Symbol;Acc:HGNC:20201]",{"v":3.183968,"d":"3.18"},{"v":0.382651,"d":"0.38"},{"v":8.32081452812093,"d":"8.32"},{"v":3.0567247613186,"d":"3.06"},{"v":1.61487470919354E-5,"d":"0.00"},{"v":0.000575748932693782,"d":"0.00"},"up","yes"]
[41700,0,"chr12","-",51281038,51324154,"ENST00000452142",12,2115,"MSTRG.3377","BIN2","GO:0005737(cytoplasm)","NA","NA","NA","bridging integrator 2 [Source:HGNC Symbol;Acc:HGNC:1053]",{"v":7.203745,"d":"7.20"},{"v":0.87965,"d":"0.88"},{"v":8.18933098391406,"d":"8.19"},{"v":3.03374559770106,"d":"3.03"},{"v":1.61756385837947E-5,"d":"0.00"},{"v":0.000575748932693782,"d":"0.00"},"up","yes"]
[191596,"j","chr9","-",89377977,89479883,"MSTRG.14836.19",18,4088,"MSTRG.14836","SEMA4D","NA","NA","NA","NA","NA",{"v":3.836862,"d":"3.84"},{"v":32.962757,"d":"32.96"},{"v":0.116399911572931,"d":"0.12"},{"v":-3.10283813263208,"d":"-3.10"},{"v":1.62299406152294e-05,"d":"0.00"},{"v":0.000576653833104806,"d":"0.00"},"down","yes"]
[31034,0,"chr11","+",65096227,65108399,"ENST00000529180",4,1027,"MSTRG.2537","VPS51","GO:0017119(Golgi transport complex);GO:0006810(transport);GO:0016021(integral component of membrane);GO:0015031(protein transport);GO:0005794(Golgi apparatus);GO:0005829(cytosol);GO:0043231(intracellular membrane-bounded organelle);GO:0005730(nucleolus);GO:0006869(lipid transport);GO:0006914(autophagy);GO:0005515(protein binding);GO:0005768(endosome);GO:0003674(molecular_function);GO:0042147(retrograde transport, endosome to Golgi);GO:0055037(recycling endosome);GO:0007030(Golgi organization);GO:0032588(trans-Golgi network membrane);GO:0048193(Golgi vesicle transport);GO:0016020(membrane);GO:0032456(endocytic recycling);GO:0007041(lysosomal transport);GO:0000938(GARP complex);GO:1990745(EARP complex);GO:0005802(trans-Golgi network)","NA","NA","NA","VPS51, GARP complex subunit [Source:HGNC Symbol;Acc:HGNC:1172]",{"v":1.1174,"d":"1.12"},{"v":10.17059,"d":"10.17"},{"v":0.109865799329242,"d":"0.11"},{"v":-3.18618574242301,"d":"-3.19"},{"v":1.63950005987725e-05,"d":"0.00"},{"v":5.81483786778488E-4,"d":"0.00"},"down","yes"]
[25826,"s","chr11","+",5225461,5234472,"MSTRG.2146.4",4,421,"MSTRG.2146","HBB","NA","NA","NA","NA","NA",{"v":301.816772,"d":"301.82"},{"v":2580.919434,"d":"2580.92"},{"v":0.116941570520949,"d":"0.12"},{"v":-3.09614022298683,"d":"-3.10"},{"v":1.65042776646497e-05,"d":"0.00"},{"v":0.000584321660297384,"d":"0.00"},"down","yes"]
[4327,0,"chr1","-",36466096,36479519,"ENST00000331941",16,2375,"MSTRG.424","CSF3R","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0007155(cell adhesion);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0004896(cytokine receptor activity);GO:0019221(cytokine-mediated signaling pathway);GO:0005887(integral component of plasma membrane);GO:0007165(signal transduction);GO:0004872(receptor activity);GO:0006952(defense response);GO:0051916(granulocyte colony-stimulating factor binding);GO:0030593(neutrophil chemotaxis);GO:0045637(regulation of myeloid cell differentiation);GO:0097186(amelogenesis)","04630(Jak-STAT signaling pathway);04151(PI3K-Akt signaling pathway);04060(Cytokine-cytokine receptor interaction);04640(Hematopoietic cell lineage);05200(Pathways in cancer)","NA","NA","colony stimulating factor 3 receptor [Source:HGNC Symbol;Acc:HGNC:2439]",{"v":2.657364,"d":"2.66"},{"v":22.946054,"d":"22.95"},{"v":0.115809193162362,"d":"0.12"},{"v":-3.11017831303415,"d":"-3.11"},{"v":1.66797884663887E-5,"d":"0.00"},{"v":0.000589490293976725,"d":"0.00"},"down","yes"]
[58370,"j","chr14","+",99481407,99510311,"MSTRG.4660.2",11,1532,"MSTRG.4660","CCNK","NA","NA","NA","NA","NA",{"v":1.060291,"d":"1.06"},{"v":9.421044,"d":"9.42"},{"v":0.112544957862419,"d":"0.11"},{"v":-3.15142667096804,"d":"-3.15"},{"v":1.70752790081976E-5,"d":"0.00"},{"v":0.000602401362607227,"d":"0.00"},"down","yes"]
[17576,0,"chr1","-",244850297,244864560,"ENST00000444376",14,6827,"MSTRG.1497","HNRNPU","GO:0005634(nucleus);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0003723(RNA binding);GO:0006397(mRNA processing);GO:0008380(RNA splicing);GO:0005737(cytoplasm);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0005654(nucleoplasm);GO:0003677(DNA binding);GO:0030529(intracellular ribonucleoprotein complex);GO:0005515(protein binding);GO:0005681(spliceosomal complex);GO:0048511(rhythmic process);GO:0001047(core promoter binding);GO:0031012(extracellular matrix);GO:0000398(mRNA splicing, via spliceosome);GO:0009986(cell surface);GO:0032922(circadian regulation of gene expression);GO:0036464(cytoplasmic ribonucleoprotein granule);GO:0070034(telomerase RNA binding);GO:0005697(telomerase holoenzyme complex);GO:0016070(RNA metabolic process);GO:0006396(RNA processing);GO:0071013(catalytic step 2 spliceosome);GO:0001649(osteoblast differentiation);GO:0070934(CRD-mediated mRNA stabilization);GO:0070937(CRD-mediated mRNA stability complex);GO:0032211(negative regulation of telomere maintenance via telomerase);GO:0034046(poly(G) binding);GO:0035326(enhancer binding);GO:0043021(ribonucleoprotein complex binding);GO:0010628(positive regulation of gene expression);GO:0055013(cardiac muscle cell development);GO:0071549(cellular response to dexamethasone stimulus);GO:2000373(positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity)","03040(Spliceosome)","K12888","NA","heterogeneous nuclear ribonucleoprotein U [Source:HGNC Symbol;Acc:HGNC:5048]",{"v":1.152151,"d":"1.15"},{"v":9.878743,"d":"9.88"},{"v":0.116629312049114,"d":"0.12"},{"v":-3.09999767312977,"d":"-3.10"},{"v":1.7345319160986e-05,"d":"0.00"},{"v":0.000610848911828165,"d":"0.00"},"down","yes"]
[112127,0,"chr2","-",88857161,88857683,"ENST00000390237",1,523,"MSTRG.8934","IGKC","NA","NA","NA","NA","immunoglobulin kappa constant [Source:HGNC Symbol;Acc:HGNC:5716]",{"v":37.152855,"d":"37.15"},{"v":4.6086,"d":"4.61"},{"v":8.06163585470642,"d":"8.06"},{"v":3.01107261791064,"d":"3.01"},{"v":1.75396668293473E-5,"d":"0.00"},{"v":0.000616605752197899,"d":"0.00"},"up","yes"]
[121361,0,"chr20","+",408065,430964,"ENST00000640614",11,2599,"MSTRG.9535","RBCK1","GO:0046872(metal ion binding);GO:0016740(transferase activity);GO:0005515(protein binding);GO:0005829(cytosol);GO:0000209(protein polyubiquitination);GO:0032088(negative regulation of NF-kappaB transcription factor activity);GO:0016032(viral process);GO:0043123(positive regulation of I-kappaB kinase/NF-kappaB signaling);GO:0043130(ubiquitin binding);GO:0051092(positive regulation of NF-kappaB transcription factor activity);GO:0007249(I-kappaB kinase/NF-kappaB signaling);GO:0004842(ubiquitin-protein transferase activity);GO:0043161(proteasome-mediated ubiquitin-dependent protein catabolic process);GO:0050852(T cell receptor signaling pathway);GO:0010803(regulation of tumor necrosis factor-mediated signaling pathway);GO:0097039(protein linear polyubiquitination);GO:0071797(LUBAC complex);GO:0042346(positive regulation of NF-kappaB import into nucleus);GO:0043065(positive regulation of apoptotic process);GO:0060546(negative regulation of necroptotic process);GO:2001238(positive regulation of extrinsic apoptotic signaling pathway)","04217(Necroptosis);04621(NOD-like receptor signaling pathway)","K10630","EC:2.3.2.27","RANBP2-type and C3HC4-type zinc finger containing 1 [Source:HGNC Symbol;Acc:HGNC:15864]",{"v":0.280737,"d":"0.28"},{"v":2.585772,"d":"2.59"},{"v":0.108569897113899,"d":"0.11"},{"v":-3.20330394851028,"d":"-3.20"},{"v":1.75919515197183e-05,"d":"0.00"},{"v":6.17356920818514E-4,"d":"0.00"},"down","yes"]
[164614,0,"chr6","+",31723373,31726714,"ENST00000375809",6,2396,"MSTRG.12880","MPIG6B","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005794(Golgi apparatus);GO:0005783(endoplasmic reticulum);GO:0005886(plasma membrane);GO:0030218(erythrocyte differentiation);GO:0007229(integrin-mediated signaling pathway);GO:0005515(protein binding);GO:0008201(heparin binding);GO:0007596(blood coagulation);GO:0030168(platelet activation);GO:0009968(negative regulation of signal transduction);GO:0030219(megakaryocyte differentiation);GO:0030220(platelet formation);GO:0035855(megakaryocyte development)","NA","NA","NA","megakaryocyte and platelet inhibitory receptor G6b [Source:HGNC Symbol;Acc:HGNC:13937]",{"v":11.889417,"d":"11.89"},{"v":1.491088,"d":"1.49"},{"v":7.97365212515962,"d":"7.97"},{"v":2.99524066474647,"d":"3.00"},{"v":1.77978568184772e-05,"d":"0.00"},{"v":0.000623487026230444,"d":"0.00"},"up","yes"]
[44616,0,"chr12","-",76047155,76084666,"ENST00000393263",16,1896,"MSTRG.3567","NAP1L1","GO:0005634(nucleus);GO:0003723(RNA binding);GO:0016020(membrane);GO:0006334(nucleosome assembly);GO:0005515(protein binding);GO:0042470(melanosome);GO:0008284(positive regulation of cell proliferation);GO:0006260(DNA replication)","NA","NA","NA","nucleosome assembly protein 1 like 1 [Source:HGNC Symbol;Acc:HGNC:7637]",{"v":4.600546,"d":"4.60"},{"v":39.131737,"d":"39.13"},{"v":0.117565596436468,"d":"0.12"},{"v":-3.08846215301272,"d":"-3.09"},{"v":1.81155102889701e-05,"d":"0.00"},{"v":0.000632363840300064,"d":"0.00"},"down","yes"]
[158484,0,"chr5","+",134758804,134829296,"ENST00000354283",23,3821,"MSTRG.12316","DDX46","GO:0003676(nucleic acid binding);GO:0016607(nuclear speck);GO:0005524(ATP binding);GO:0001650(fibrillar center);GO:0003723(RNA binding);GO:0005634(nucleus);GO:0006397(mRNA processing);GO:0008380(RNA splicing);GO:0016020(membrane);GO:0000166(nucleotide binding);GO:0016787(hydrolase activity);GO:0004386(helicase activity);GO:0005737(cytoplasm);GO:0005730(nucleolus);GO:0005654(nucleoplasm);GO:0004004(ATP-dependent RNA helicase activity);GO:0010501(RNA secondary structure unwinding);GO:0000398(mRNA splicing, via spliceosome);GO:0010468(regulation of gene expression);GO:0015030(Cajal body)","03040(Spliceosome)","K12811","EC:3.6.4.13","DEAD-box helicase 46 [Source:HGNC Symbol;Acc:HGNC:18681]",{"v":10.062304,"d":"10.06"},{"v":1.273158,"d":"1.27"},{"v":7.90342125643479,"d":"7.90"},{"v":2.98247730660868,"d":"2.98"},{"v":1.81234373259525e-05,"d":"0.00"},{"v":0.000632363840300064,"d":"0.00"},"up","yes"]
[1601,0,"chr1","-",11785723,11805413,"ENST00000376592",12,8378,"ENSG00000177000","MTHFR","GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0003824(catalytic activity);GO:0008152(metabolic process);GO:0035999(tetrahydrofolate interconversion);GO:0005829(cytosol);GO:0004489(methylenetetrahydrofolate reductase (NAD(P)H) activity);GO:0006555(methionine metabolic process);GO:0006520(cellular amino acid metabolic process);GO:0046655(folic acid metabolic process);GO:0008015(blood circulation);GO:0050660(flavin adenine dinucleotide binding);GO:0072341(modified amino acid binding);GO:0050667(homocysteine metabolic process);GO:0032403(protein complex binding);GO:0031060(regulation of histone methylation);GO:0070829(heterochromatin maintenance);GO:0050661(NADP binding);GO:0001666(response to hypoxia);GO:0033274(response to vitamin B2);GO:0042493(response to drug);GO:0043200(response to amino acid);GO:0046500(S-adenosylmethionine metabolic process);GO:0046653(tetrahydrofolate metabolic process);GO:0051593(response to folic acid);GO:0070555(response to interleukin-1);GO:0045202(synapse)","00670(One carbon pool by folate);01523(Antifolate resistance)","NA","NA","methylenetetrahydrofolate reductase [Source:HGNC Symbol;Acc:HGNC:7436]",{"v":0.110566,"d":"0.11"},{"v":1.003006,"d":"1.00"},{"v":0.110234634688127,"d":"0.11"},{"v":-3.18135051850683,"d":"-3.18"},{"v":1.81462580374568e-05,"d":"0.00"},{"v":0.000632363840300064,"d":"0.00"},"down","yes"]
[129347,0,"chr22","-",23638487,23717321,"ENST00000451837",12,3234,"MSTRG.10235","GUSBP11","NA","NA","NA","NA","glucuronidase, beta pseudogene 11 [Source:HGNC Symbol;Acc:HGNC:42325]",{"v":2.285299,"d":"2.29"},{"v":0.271838,"d":"0.27"},{"v":8.40684157476144,"d":"8.41"},{"v":3.07156388605945,"d":"3.07"},{"v":1.84108191655724e-05,"d":"0.00"},{"v":6.40465569857404E-4,"d":"0.00"},"up","yes"]
[4877,0,"chr1","+",42456559,42460414,"ENST00000372561",3,1431,"ENSG00000127125","PPCS","GO:0016874(ligase activity);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0009108(coenzyme biosynthetic process);GO:0015937(coenzyme A biosynthetic process);GO:0004632(phosphopantothenate--cysteine ligase activity)","00770(Pantothenate and CoA biosynthesis)","K01922","EC:6.3.2.51","phosphopantothenoylcysteine synthetase [Source:HGNC Symbol;Acc:HGNC:25686]",{"v":1.513703,"d":"1.51"},{"v":13.128938,"d":"13.13"},{"v":0.115295159440924,"d":"0.12"},{"v":-3.11659615082369,"d":"-3.12"},{"v":1.84838814237072e-05,"d":"0.00"},{"v":0.000641888946554062,"d":"0.00"},"down","yes"]
[200994,0,"chrX","-",153802166,153830490,"ENST00000164640",8,3689,"ENSG00000067840","PDZD4","GO:0005737(cytoplasm);GO:0005938(cell cortex);GO:0005515(protein binding)","NA","NA","NA","PDZ domain containing 4 [Source:HGNC Symbol;Acc:HGNC:21167]",{"v":2.417007,"d":"2.42"},{"v":0.291569,"d":"0.29"},{"v":8.28965699371332,"d":"8.29"},{"v":3.05131240766716,"d":"3.05"},{"v":1.87530734097994E-5,"d":"0.00"},{"v":0.000649137766636531,"d":"0.00"},"up","yes"]
[24721,0,"chr11","+",313506,315272,"ENST00000528780",3,730,"MSTRG.2061","IFITM1","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005886(plasma membrane);GO:0002376(immune system process);GO:0045087(innate immune response);GO:0050776(regulation of immune response);GO:0009607(response to biotic stimulus);GO:0051607(defense response to virus);GO:0005515(protein binding);GO:0008285(negative regulation of cell proliferation);GO:0009615(response to virus);GO:0045071(negative regulation of viral genome replication);GO:0001503(ossification);GO:0007166(cell surface receptor signaling pathway);GO:0046597(negative regulation of viral entry into host cell);GO:0060337(type I interferon signaling pathway);GO:0005057(signal transducer activity, downstream of receptor);GO:0035456(response to interferon-beta);GO:0030336(negative regulation of cell migration);GO:0034341(response to interferon-gamma);GO:0045669(positive regulation of osteoblast differentiation);GO:0035455(response to interferon-alpha)","04662(B cell receptor signaling pathway)","NA","NA","interferon induced transmembrane protein 1 [Source:HGNC Symbol;Acc:HGNC:5412]",{"v":1.782739,"d":"1.78"},{"v":15.842651,"d":"15.84"},{"v":0.112527821259207,"d":"0.11"},{"v":-3.15164635895178,"d":"-3.15"},{"v":1.8757636786322E-5,"d":"0.00"},{"v":0.000649137766636531,"d":"0.00"},"down","yes"]
[94100,0,"chr19","+",1031137,1038309,"ENST00000568865",7,1332,"MSTRG.7591","CNN2","GO:0016020(membrane);GO:0003779(actin binding);GO:0005856(cytoskeleton);GO:0005925(focal adhesion);GO:0005576(extracellular region);GO:0007010(cytoskeleton organization);GO:0005516(calmodulin binding);GO:0031032(actomyosin structure organization);GO:0045296(cadherin binding);GO:0070062(extracellular exosome);GO:0043312(neutrophil degranulation);GO:0035722(interleukin-12-mediated signaling pathway);GO:0035580(specific granule lumen);GO:1904724(tertiary granule lumen);GO:0005911(cell-cell junction);GO:0001725(stress fiber);GO:0032970(regulation of actin filament-based process);GO:0071260(cellular response to mechanical stimulus);GO:0010628(positive regulation of gene expression);GO:0030097(hemopoiesis);GO:0030336(negative regulation of cell migration);GO:0042060(wound healing);GO:0042127(regulation of cell proliferation);GO:0050765(negative regulation of phagocytosis)","NA","NA","NA","calponin 2 [Source:HGNC Symbol;Acc:HGNC:2156]",{"v":0.786147,"d":"0.79"},{"v":7.014719,"d":"7.01"},{"v":0.112071060865018,"d":"0.11"},{"v":-3.15751430324247,"d":"-3.16"},{"v":1.89688170825896e-05,"d":"0.00"},{"v":0.000655310275960467,"d":"0.00"},"down","yes"]
[80111,0,"chr17","-",17812073,17836987,"ENST00000355815",20,4253,"ENSG00000072310","SREBF1","GO:0046983(protein dimerization activity);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0005794(Golgi apparatus);GO:0006629(lipid metabolic process);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0008202(steroid metabolic process);GO:0030522(intracellular receptor signaling pathway);GO:0000139(Golgi membrane);GO:0031410(cytoplasmic vesicle);GO:0008203(cholesterol metabolic process);GO:0005515(protein binding);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:1903146(regulation of mitophagy);GO:1903214(regulation of protein targeting to mitochondrion);GO:0005635(nuclear envelope);GO:0007623(circadian rhythm);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0045540(regulation of cholesterol biosynthetic process);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0000977(RNA polymerase II regulatory region sequence-specific DNA binding);GO:0031647(regulation of protein stability);GO:0012507(ER to Golgi transport vesicle membrane);GO:0010867(positive regulation of triglyceride biosynthetic process);GO:0008610(lipid biosynthetic process);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:0000982(transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0001077(transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0003682(chromatin binding);GO:0004879(RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding);GO:0019901(protein kinase binding);GO:0032403(protein complex binding);GO:0032810(sterol response element binding);GO:0043565(sequence-specific DNA binding);GO:0044212(transcription regulatory region DNA binding);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0003062(regulation of heart rate by chemical signal);GO:0007568(aging);GO:0008286(insulin receptor signaling pathway);GO:0009267(cellular response to starvation);GO:0009749(response to glucose);GO:0014070(response to organic cyclic compound);GO:0019217(regulation of fatty acid metabolic process);GO:0030324(lung development);GO:0031065(positive regulation of histone deacetylation);GO:0032094(response to food);GO:0032526(response to retinoic acid);GO:0032570(response to progesterone);GO:0032869(cellular response to insulin stimulus);GO:0033762(response to glucagon);GO:0033993(response to lipid);GO:0042493(response to drug);GO:0042789(mRNA transcription from RNA polymerase II promoter);GO:0043434(response to peptide hormone);GO:0045444(fat cell differentiation);GO:0045542(positive regulation of cholesterol biosynthetic process);GO:0045893(positive regulation of transcription, DNA-templated);GO:0046676(negative regulation of insulin secretion);GO:0050796(regulation of insulin secretion);GO:0051591(response to cAMP);GO:0070542(response to fatty acid);GO:0071398(cellular response to fatty acid);GO:0043231(intracellular membrane-bounded organelle);GO:0043234(protein complex)","04152(AMPK signaling pathway);04910(Insulin signaling pathway);04932(Non-alcoholic fatty liver disease (NAFLD));04931(Insulin resistance)","K07197","NA","sterol regulatory element binding transcription factor 1 [Source:HGNC Symbol;Acc:HGNC:11289]",{"v":1.458091,"d":"1.46"},{"v":0.173598,"d":"0.17"},{"v":8.39923847048929,"d":"8.40"},{"v":3.07025852971846,"d":"3.07"},{"v":1.91709188952905E-5,"d":"0.00"},{"v":0.000661148373922558,"d":"0.00"},"up","yes"]
[163013,0,"chr6","+",15246296,15522021,"ENST00000341776",18,5755,"MSTRG.12683","JARID2","GO:0005634(nucleus);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0016569(covalent chromatin modification);GO:0005739(mitochondrion);GO:0003677(DNA binding);GO:0007275(multicellular organism development);GO:0030154(cell differentiation);GO:0005654(nucleoplasm);GO:0003682(chromatin binding);GO:0035098(ESC/E(Z) complex);GO:0048863(stem cell differentiation);GO:0007417(central nervous system development);GO:0045892(negative regulation of transcription, DNA-templated);GO:0035097(histone methyltransferase complex);GO:0045814(negative regulation of gene expression, epigenetic);GO:0051574(positive regulation of histone H3-K9 methylation);GO:0000977(RNA polymerase II regulatory region sequence-specific DNA binding);GO:0001227(transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding);GO:0008134(transcription factor binding);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0001889(liver development);GO:0008285(negative regulation of cell proliferation);GO:0010614(negative regulation of cardiac muscle hypertrophy);GO:0031061(negative regulation of histone methylation);GO:0042127(regulation of cell proliferation);GO:0048536(spleen development);GO:0048538(thymus development);GO:0060044(negative regulation of cardiac muscle cell proliferation);GO:1990830(cellular response to leukemia inhibitory factor)","04550(Signaling pathways regulating pluripotency of stem cells)","K11478","NA","jumonji and AT-rich interaction domain containing 2 [Source:HGNC Symbol;Acc:HGNC:6196]",{"v":1.398926,"d":"1.40"},{"v":11.82507,"d":"11.83"},{"v":0.118301709841887,"d":"0.12"},{"v":-3.07945716945493,"d":"-3.08"},{"v":1.92597773429568e-05,"d":"0.00"},{"v":0.000663067644800278,"d":"0.00"},"down","yes"]
[182165,0,"chr8","+",23102590,23117437,"ENST00000356864",5,1718,"MSTRG.14241","TNFRSF10C","GO:0016020(membrane);GO:0005886(plasma membrane);GO:0006915(apoptotic process);GO:0031225(anchored component of membrane);GO:0006955(immune response);GO:0006954(inflammatory response);GO:0097190(apoptotic signaling pathway);GO:0005887(integral component of plasma membrane);GO:0045569(TRAIL binding);GO:0033209(tumor necrosis factor-mediated signaling pathway);GO:0007165(signal transduction);GO:0005031(tumor necrosis factor-activated receptor activity);GO:0007275(multicellular organism development);GO:0032496(response to lipopolysaccharide);GO:0042127(regulation of cell proliferation);GO:0042981(regulation of apoptotic process);GO:0043154(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process);GO:0004888(transmembrane signaling receptor activity)","04060(Cytokine-cytokine receptor interaction);04210(Apoptosis);04217(Necroptosis);04650(Natural killer cell mediated cytotoxicity);05162(Measles);05164(Influenza A)","K04722","NA","TNF receptor superfamily member 10c [Source:HGNC Symbol;Acc:HGNC:11906]",{"v":17.818701,"d":"17.82"},{"v":149.564026,"d":"149.56"},{"v":0.119137612676995,"d":"0.12"},{"v":-3.06929913965386,"d":"-3.07"},{"v":1.9371133478546E-5,"d":"0.00"},{"v":0.000665753516866792,"d":"0.00"},"down","yes"]
[11533,0,"chr1","+",155051286,155062758,"ENST00000449910",23,2946,"ENSG00000143537","ADAM15","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0046872(metal ion binding);GO:0016787(hydrolase activity);GO:0007155(cell adhesion);GO:0042995(cell projection);GO:0005515(protein binding);GO:0008233(peptidase activity);GO:0006508(proteolysis);GO:0030054(cell junction);GO:0004222(metalloendopeptidase activity);GO:0008237(metallopeptidase activity);GO:0031410(cytoplasmic vesicle);GO:0007229(integrin-mediated signaling pathway);GO:0045087(innate immune response);GO:0005886(plasma membrane);GO:0070062(extracellular exosome);GO:0012505(endomembrane system);GO:0005912(adherens junction);GO:0001669(acrosomal vesicle);GO:0017124(SH3 domain binding);GO:0009986(cell surface);GO:0030308(negative regulation of cell growth);GO:0005178(integrin binding);GO:0030198(extracellular matrix organization);GO:0001525(angiogenesis);GO:0022617(extracellular matrix disassembly);GO:0001953(negative regulation of cell-matrix adhesion);GO:0030574(collagen catabolic process);GO:0030336(negative regulation of cell migration);GO:0007160(cell-matrix adhesion);GO:0070528(protein kinase C signaling);GO:1900121(negative regulation of receptor binding);GO:0008584(male gonad development);GO:0042246(tissue regeneration);GO:0060317(cardiac epithelial to mesenchymal transition);GO:0005615(extracellular space)","NA","NA","NA","ADAM metallopeptidase domain 15 [Source:HGNC Symbol;Acc:HGNC:193]",{"v":0.297281,"d":"0.30"},{"v":2.689744,"d":"2.69"},{"v":0.110523901159367,"d":"0.11"},{"v":-3.17756970395492,"d":"-3.18"},{"v":1.96623909396436e-05,"d":"0.00"},{"v":0.000674602443784886,"d":"0.00"},"down","yes"]
[45055,0,"chr12","-",89588072,89708831,"ENST00000428670",21,7032,"MSTRG.3587","ATP2B1","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0005634(nucleus);GO:0016787(hydrolase activity);GO:0005886(plasma membrane);GO:0006811(ion transport);GO:0005388(calcium-transporting ATPase activity);GO:0006816(calcium ion transport);GO:0070588(calcium ion transmembrane transport);GO:0099132(ATP hydrolysis coupled cation transmembrane transport);GO:0005516(calmodulin binding);GO:0005515(protein binding);GO:0070062(extracellular exosome);GO:0034220(ion transmembrane transport);GO:0005887(integral component of plasma membrane);GO:1903779(regulation of cardiac conduction);GO:0043231(intracellular membrane-bounded organelle);GO:0015085(calcium ion transmembrane transporter activity);GO:0030165(PDZ domain binding);GO:0051480(regulation of cytosolic calcium ion concentration);GO:1990034(calcium ion export from cell);GO:0003407(neural retina development);GO:0007420(brain development);GO:0007568(aging);GO:0009409(response to cold);GO:0071305(cellular response to vitamin D);GO:0071386(cellular response to corticosterone stimulus);GO:1901660(calcium ion export);GO:0009898(cytoplasmic side of plasma membrane);GO:0016323(basolateral plasma membrane);GO:0016324(apical plasma membrane);GO:0032590(dendrite membrane);GO:0032591(dendritic spine membrane);GO:0032809(neuronal cell body membrane);GO:0045121(membrane raft);GO:0045177(apical part of cell)","04020(Calcium signaling pathway);04024(cAMP signaling pathway);04022(cGMP - PKG signaling pathway);04925(Aldosterone synthesis and secretion);04261(Adrenergic signaling in cardiomyocytes);04970(Salivary secretion);04972(Pancreatic secretion);04978(Mineral absorption);04961(Endocrine and other factor-regulated calcium reabsorption)","NA","NA","ATPase plasma membrane Ca2+ transporting 1 [Source:HGNC Symbol;Acc:HGNC:814]",{"v":0.462822,"d":"0.46"},{"v":3.946921,"d":"3.95"},{"v":0.11726153120369,"d":"0.12"},{"v":-3.09219829417331,"d":"-3.09"},{"v":1.97843785507159e-05,"d":"0.00"},{"v":0.000677623449229322,"d":"0.00"},"down","yes"]
[16535,0,"chr1","+",226063977,226072001,"ENST00000366813",3,1308,"MSTRG.1426","H3F3A","GO:0005634(nucleus);GO:0003677(DNA binding);GO:0046982(protein heterodimerization activity);GO:0006334(nucleosome assembly);GO:0000786(nucleosome);GO:0005694(chromosome);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0005654(nucleoplasm);GO:0070062(extracellular exosome);GO:0044267(cellular protein metabolic process);GO:1902036(regulation of hematopoietic stem cell differentiation);GO:0043234(protein complex);GO:0000784(nuclear chromosome, telomeric region);GO:0045815(positive regulation of gene expression, epigenetic);GO:0042393(histone binding);GO:0030307(positive regulation of cell growth);GO:0045652(regulation of megakaryocyte differentiation);GO:0006336(DNA replication-independent nucleosome assembly);GO:0007596(blood coagulation);GO:0000228(nuclear chromosome);GO:0060964(regulation of gene silencing by miRNA);GO:0000183(chromatin silencing at rDNA);GO:0045814(negative regulation of gene expression, epigenetic);GO:0000979(RNA polymerase II core promoter sequence-specific DNA binding);GO:0031492(nucleosomal DNA binding);GO:0000980(RNA polymerase II distal enhancer sequence-specific DNA binding);GO:0000788(nuclear nucleosome);GO:0032200(telomere organization);GO:0001649(osteoblast differentiation);GO:0006997(nucleus organization);GO:0007283(spermatogenesis);GO:0007286(spermatid development);GO:0007338(single fertilization);GO:0007420(brain development);GO:0007566(embryo implantation);GO:0008283(cell proliferation);GO:0008584(male gonad development);GO:0009725(response to hormone);GO:0031508(pericentric heterochromatin assembly);GO:0031509(telomeric heterochromatin assembly);GO:0035264(multicellular organism growth);GO:0042692(muscle cell differentiation);GO:0048477(oogenesis);GO:0090230(regulation of centromere complex assembly);GO:1902340(negative regulation of chromosome condensation);GO:0001740(Barr body)","05202(Transcriptional misregulation in cancers);05322(Systemic lupus erythematosus);05034(Alcoholism)","NA","NA","H3 histone family member 3A [Source:HGNC Symbol;Acc:HGNC:4764]",{"v":5.526683,"d":"5.53"},{"v":0.668951,"d":"0.67"},{"v":8.26171573104757,"d":"8.26"},{"v":3.04644142082542,"d":"3.05"},{"v":1.98755340620565e-05,"d":"0.00"},{"v":6.79579904368399E-4,"d":"0.00"},"up","yes"]
[161195,0,"chr5","+",173888280,173961976,"ENST00000265085",10,9483,"MSTRG.12547","CPEB4","GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0046872(metal ion binding);GO:0005783(endoplasmic reticulum);GO:0005886(plasma membrane);GO:0042995(cell projection);GO:0005515(protein binding);GO:0003730(mRNA 3'-UTR binding);GO:0045182(translation regulator activity);GO:0006417(regulation of translation);GO:0048471(perinuclear region of cytoplasm);GO:0030054(cell junction);GO:0045202(synapse);GO:0045211(postsynaptic membrane);GO:0030425(dendrite);GO:0071230(cellular response to amino acid stimulus);GO:0030424(axon);GO:0030426(growth cone);GO:0014069(postsynaptic density);GO:0043197(dendritic spine);GO:0000900(translation repressor activity, nucleic acid binding);GO:0008135(translation factor activity, RNA binding);GO:0043022(ribosome binding);GO:2000766(negative regulation of cytoplasmic translation);GO:0043005(neuron projection);GO:1990124(messenger ribonucleoprotein complex);GO:0043524(negative regulation of neuron apoptotic process);GO:0002931(response to ischemia);GO:0042149(cellular response to glucose starvation);GO:0035235(ionotropic glutamate receptor signaling pathway);GO:0006412(translation);GO:0036294(cellular response to decreased oxygen levels)","04114(Oocyte meiosis);04914(Progesterone-mediated oocyte maturation)","K02602","NA","cytoplasmic polyadenylation element binding protein 4 [Source:HGNC Symbol;Acc:HGNC:21747]",{"v":1.221552,"d":"1.22"},{"v":0.152416,"d":"0.15"},{"v":8.0145916439219,"d":"8.01"},{"v":3.00262901466589,"d":"3.00"},{"v":2.02670465744888e-05,"d":"0.00"},{"v":0.000691781856409216,"d":"0.00"},"up","yes"]
[38815,0,"chr12","+",10304446,10329600,"ENST00000381908",7,15549,"MSTRG.3166","KLRD1","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0030246(carbohydrate binding);GO:0005515(protein binding);GO:0050776(regulation of immune response);GO:0005886(plasma membrane);GO:0045087(innate immune response);GO:0043235(receptor complex);GO:0007166(cell surface receptor signaling pathway);GO:0004888(transmembrane signaling receptor activity);GO:0023024(MHC class I protein complex binding);GO:1990405(protein antigen binding);GO:0002228(natural killer cell mediated immunity);GO:0023030(MHC class Ib protein binding, via antigen binding groove);GO:0009897(external side of plasma membrane)","04650(Natural killer cell mediated cytotoxicity);04612(Antigen processing and presentation);05332(Graft-versus-host disease)","K06516","NA","killer cell lectin like receptor D1 [Source:HGNC Symbol;Acc:HGNC:6378]",{"v":1.616192,"d":"1.62"},{"v":0.20678,"d":"0.21"},{"v":7.81599767869233,"d":"7.82"},{"v":2.96643003883399,"d":"2.97"},{"v":2.05063919404764e-05,"d":"0.00"},{"v":0.000698757055063879,"d":"0.00"},"up","yes"]
[175030,0,"chr7","+",74209981,74226508,"ENST00000398475",13,2453,"MSTRG.13713","LAT2","GO:0042113(B cell activation);GO:0002764(immune response-regulating signaling pathway);GO:0005622(intracellular);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005886(plasma membrane);GO:0002376(immune system process);GO:0002250(adaptive immune response);GO:0038095(Fc-epsilon receptor signaling pathway);GO:0042629(mast cell granule);GO:0070062(extracellular exosome);GO:0005515(protein binding);GO:0043303(mast cell degranulation);GO:0019722(calcium-mediated signaling);GO:0035556(intracellular signal transduction);GO:0045121(membrane raft);GO:0042169(SH2 domain binding);GO:0050853(B cell receptor signaling pathway)","NA","NA","NA","linker for activation of T-cells family member 2 [Source:HGNC Symbol;Acc:HGNC:12749]",{"v":0.780852,"d":"0.78"},{"v":6.710027,"d":"6.71"},{"v":0.116370917732522,"d":"0.12"},{"v":-3.10319753565621,"d":"-3.10"},{"v":2.15591975222944E-5,"d":"0.00"},{"v":0.000732930563329329,"d":"0.00"},"down","yes"]
[159617,0,"chr5","-",143281162,143403689,"ENST00000231509",9,3556,"MSTRG.12423","NR3C1","GO:0005634(nucleus);GO:0003723(RNA binding);GO:0005737(cytoplasm);GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0016569(covalent chromatin modification);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0051301(cell division);GO:0005739(mitochondrion);GO:0043565(sequence-specific DNA binding);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0003707(steroid hormone receptor activity);GO:0043401(steroid hormone mediated signaling pathway);GO:0007049(cell cycle);GO:0006915(apoptotic process);GO:0005815(microtubule organizing center);GO:0005819(spindle);GO:0005496(steroid binding);GO:0007059(chromosome segregation);GO:0008289(lipid binding);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0043234(protein complex);GO:0004883(glucocorticoid receptor activity);GO:0042921(glucocorticoid receptor signaling pathway);GO:0043402(glucocorticoid mediated signaling pathway);GO:0007165(signal transduction);GO:0006366(transcription from RNA polymerase II promoter);GO:0006367(transcription initiation from RNA polymerase II promoter);GO:0001077(transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0051879(Hsp90 protein binding);GO:0071383(cellular response to steroid hormone stimulus);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0001047(core promoter binding);GO:0032183(SUMO binding);GO:0038051(glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity);GO:1990239(steroid hormone binding);GO:0071549(cellular response to dexamethasone stimulus);GO:0071560(cellular response to transforming growth factor beta stimulus);GO:0005759(mitochondrial matrix)","04080(Neuroactive ligand-receptor interaction)","K05771","NA","nuclear receptor subfamily 3 group C member 1 [Source:HGNC Symbol;Acc:HGNC:7978]",{"v":0.281171,"d":"0.28"},{"v":2.478072,"d":"2.48"},{"v":0.113463612033871,"d":"0.11"},{"v":-3.13969839785819,"d":"-3.14"},{"v":2.15826908672699e-05,"d":"0.00"},{"v":0.000732930563329329,"d":"0.00"},"down","yes"]
[134758,0,"chr3","+",37988059,38007188,"ENST00000283713",20,2970,"ENSG00000136059","VILL","GO:0003779(actin binding);GO:0051015(actin filament binding);GO:0051693(actin filament capping);GO:0007010(cytoskeleton organization);GO:0005200(structural constituent of cytoskeleton);GO:0015629(actin cytoskeleton)","NA","NA","NA","villin like [Source:HGNC Symbol;Acc:HGNC:30906]",{"v":0.259036,"d":"0.26"},{"v":2.303522,"d":"2.30"},{"v":0.112452149360848,"d":"0.11"},{"v":-3.15261685847059,"d":"-3.15"},{"v":2.18940016191657e-05,"d":"0.00"},{"v":7.42240109221564E-4,"d":"0.00"},"down","yes"]
[26024,0,"chr11","-",6395125,6419414,"ENST00000311051",14,2619,"MSTRG.2200","APBB1","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016607(nuclear speck);GO:0016020(membrane);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0016569(covalent chromatin modification);GO:0005886(plasma membrane);GO:0042995(cell projection);GO:0005515(protein binding);GO:0007165(signal transduction);GO:0006974(cellular response to DNA damage stimulus);GO:0006915(apoptotic process);GO:0045202(synapse);GO:0045893(positive regulation of transcription, DNA-templated);GO:0005654(nucleoplasm);GO:0008134(transcription factor binding);GO:0007409(axonogenesis);GO:0030027(lamellipodium);GO:0030426(growth cone);GO:0001540(amyloid-beta binding);GO:0003682(chromatin binding);GO:0007050(cell cycle arrest);GO:0043065(positive regulation of apoptotic process);GO:0042393(histone binding);GO:0070064(proline-rich region binding);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0030308(negative regulation of cell growth);GO:0043967(histone H4 acetylation);GO:0050760(negative regulation of thymidylate synthase biosynthetic process);GO:0032403(protein complex binding);GO:0048156(tau protein binding);GO:0006302(double-strand break repair);GO:0010039(response to iron ion);GO:0010976(positive regulation of neuron projection development);GO:0045739(positive regulation of DNA repair);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0050714(positive regulation of protein secretion);GO:0042734(presynaptic membrane);GO:0043025(neuronal cell body);GO:0043197(dendritic spine);GO:0043234(protein complex);GO:0044304(main axon);GO:0045211(postsynaptic membrane);GO:0048471(perinuclear region of cytoplasm);GO:1990761(growth cone lamellipodium);GO:1990812(growth cone filopodium)","05010(Alzheimer's disease)","K04529","NA","amyloid beta precursor protein binding family B member 1 [Source:HGNC Symbol;Acc:HGNC:581]",{"v":0.249183,"d":"0.25"},{"v":2.232919,"d":"2.23"},{"v":0.111595181016418,"d":"0.11"},{"v":-3.1636533658728,"d":"-3.16"},{"v":2.21192526812546e-05,"d":"0.00"},{"v":0.00074860548735473,"d":"0.00"},"down","yes"]
[66615,0,"chr15","+",91853695,92165903,"ENST00000318445",10,5115,"MSTRG.5445","SLCO3A1","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005215(transporter activity);GO:0006811(ion transport);GO:0005886(plasma membrane);GO:0015347(sodium-independent organic anion transmembrane transporter activity);GO:0043252(sodium-independent organic anion transport);GO:0005887(integral component of plasma membrane);GO:0015732(prostaglandin transport)","NA","NA","NA","solute carrier organic anion transporter family member 3A1 [Source:HGNC Symbol;Acc:HGNC:10952]",{"v":0.924826,"d":"0.92"},{"v":7.735561,"d":"7.74"},{"v":0.11955512987358,"d":"0.12"},{"v":-3.06425206032595,"d":"-3.06"},{"v":2.22159436977967e-05,"d":"0.00"},{"v":0.000749883292377601,"d":"0.00"},"down","yes"]
[94095,0,"chr19","+",1026629,1039068,"ENST00000562958",7,2194,"MSTRG.7591","CNN2","GO:0016020(membrane);GO:0003779(actin binding);GO:0005856(cytoskeleton);GO:0005925(focal adhesion);GO:0005576(extracellular region);GO:0007010(cytoskeleton organization);GO:0005516(calmodulin binding);GO:0031032(actomyosin structure organization);GO:0045296(cadherin binding);GO:0070062(extracellular exosome);GO:0043312(neutrophil degranulation);GO:0035722(interleukin-12-mediated signaling pathway);GO:0035580(specific granule lumen);GO:1904724(tertiary granule lumen);GO:0005911(cell-cell junction);GO:0001725(stress fiber);GO:0032970(regulation of actin filament-based process);GO:0071260(cellular response to mechanical stimulus);GO:0010628(positive regulation of gene expression);GO:0030097(hemopoiesis);GO:0030336(negative regulation of cell migration);GO:0042060(wound healing);GO:0042127(regulation of cell proliferation);GO:0050765(negative regulation of phagocytosis)","NA","NA","NA","calponin 2 [Source:HGNC Symbol;Acc:HGNC:2156]",{"v":3.33959,"d":"3.34"},{"v":27.796186,"d":"27.80"},{"v":0.120145619978223,"d":"0.12"},{"v":-3.05714404026793,"d":"-3.06"},{"v":2.22321168413231e-05,"d":"0.00"},{"v":0.000749883292377601,"d":"0.00"},"down","yes"]
[35342,0,"chr11","+",114400529,114408924,"ENST00000375490",5,2064,"MSTRG.2862","RBM7","GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0051321(meiotic cell cycle);GO:0005654(nucleoplasm);GO:0005515(protein binding);GO:0000381(regulation of alternative mRNA splicing, via spliceosome);GO:0003727(single-stranded RNA binding)","NA","NA","NA","RNA binding motif protein 7 [Source:HGNC Symbol;Acc:HGNC:9904]",{"v":0.409399,"d":"0.41"},{"v":3.634118,"d":"3.63"},{"v":0.112654294659667,"d":"0.11"},{"v":-3.15002578117109,"d":"-3.15"},{"v":2.23418702465572e-05,"d":"0.00"},{"v":0.000752314443647983,"d":"0.00"},"down","yes"]
[124667,0,"chr20","-",51386957,51542719,"ENST00000371564",11,7525,"MSTRG.9832","NFATC2","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0006355(regulation of transcription, DNA-templated);GO:0006366(transcription from RNA polymerase II promoter);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0005515(protein binding);GO:0006974(cellular response to DNA damage stimulus);GO:0038095(Fc-epsilon receptor signaling pathway);GO:0030890(positive regulation of B cell proliferation);GO:0050853(B cell receptor signaling pathway);GO:0016477(cell migration);GO:0045893(positive regulation of transcription, DNA-templated);GO:0042493(response to drug);GO:0045589(regulation of regulatory T cell differentiation);GO:0000976(transcription regulatory region sequence-specific DNA binding);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:0000981(RNA polymerase II transcription factor activity, sequence-specific DNA binding);GO:0001077(transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0001078(transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0003682(chromatin binding);GO:0008134(transcription factor binding);GO:0043565(sequence-specific DNA binding);GO:0044212(transcription regulatory region DNA binding);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0001816(cytokine production);GO:0010628(positive regulation of gene expression);GO:0014904(myotube cell development);GO:0033173(calcineurin-NFAT signaling cascade);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:1901741(positive regulation of myoblast fusion);GO:0000790(nuclear chromatin);GO:0005667(transcription factor complex);GO:0030529(intracellular ribonucleoprotein complex);GO:0044798(nuclear transcription factor complex)","04310(Wnt signaling pathway);04370(VEGF signaling pathway);04022(cGMP - PKG signaling pathway);04218(Cellular senescence);04650(Natural killer cell mediated cytotoxicity);04660(T cell receptor signaling pathway);04658(Th1 and Th2 cell differentiation);04659(Th17 cell differentiation);04662(B cell receptor signaling pathway);04921(Oxytocin signaling pathway);04360(Axon guidance);04380(Osteoclast differentiation);05166(HTLV-I infection);05161(Hepatitis B);05167(Kaposi's sarcoma-associated herpesvirus infection)","K17332","NA","nuclear factor of activated T-cells 2 [Source:HGNC Symbol;Acc:HGNC:7776]",{"v":6.990311,"d":"6.99"},{"v":0.911485,"d":"0.91"},{"v":7.66914540557442,"d":"7.67"},{"v":2.93906582312182,"d":"2.94"},{"v":2.24885656303191e-05,"d":"0.00"},{"v":0.000755979256744465,"d":"0.00"},"up","yes"]
[77032,0,"chr16","-",89707134,89720986,"ENST00000389386",15,2748,"MSTRG.6253","VPS9D1","GO:0043547(positive regulation of GTPase activity);GO:0005096(GTPase activator activity);GO:0005215(transporter activity);GO:0015986(ATP synthesis coupled proton transport)","NA","NA","NA","VPS9 domain containing 1 [Source:HGNC Symbol;Acc:HGNC:13526]",{"v":0.271105,"d":"0.27"},{"v":2.3977,"d":"2.40"},{"v":0.113068774241982,"d":"0.11"},{"v":-3.14472753396108,"d":"-3.14"},{"v":2.32677268389997e-05,"d":"0.00"},{"v":0.000780770230646732,"d":"0.00"},"down","yes"]
[145484,0,"chr4","-",2938113,2963333,"ENST00000398071",17,2535,"MSTRG.11511","NOP14","GO:0003723(RNA binding);GO:0005634(nucleus);GO:0016020(membrane);GO:0005730(nucleolus);GO:0005739(mitochondrion);GO:0042254(ribosome biogenesis);GO:0006364(rRNA processing);GO:0032040(small-subunit processome);GO:0042274(ribosomal small subunit biogenesis);GO:0005654(nucleoplasm);GO:0019899(enzyme binding);GO:0030490(maturation of SSU-rRNA);GO:0000447(endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA));GO:0000472(endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA));GO:0000480(endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA));GO:0030686(90S preribosome);GO:0030515(snoRNA binding);GO:0000462(maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA));GO:0030692(Noc4p-Nop14p complex)","NA","NA","NA","NOP14 nucleolar protein [Source:HGNC Symbol;Acc:HGNC:16821]",{"v":0.249698,"d":"0.25"},{"v":2.252305,"d":"2.25"},{"v":0.110863315581149,"d":"0.11"},{"v":-3.17314603492854,"d":"-3.17"},{"v":2.33042396567234E-5,"d":"0.00"},{"v":0.000780770230646732,"d":"0.00"},"down","yes"]
[124605,0,"chr20","+",50190734,50192689,"ENST00000303004",1,1956,"MSTRG.9818","CEBPB","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005654(nucleoplasm);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0042803(protein homodimerization activity);GO:0005515(protein binding);GO:0030154(cell differentiation);GO:0042742(defense response to bacterium);GO:0006954(inflammatory response);GO:0006955(immune response);GO:0032753(positive regulation of interleukin-4 production);GO:0006366(transcription from RNA polymerase II promoter);GO:0046982(protein heterodimerization activity);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0034976(response to endoplasmic reticulum stress);GO:0070059(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress);GO:1990440(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress);GO:0045600(positive regulation of fat cell differentiation);GO:0042130(negative regulation of T cell proliferation);GO:0003705(transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding);GO:0001541(ovarian follicle development);GO:0006953(acute-phase response);GO:0045670(regulation of osteoclast differentiation);GO:0000977(RNA polymerase II regulatory region sequence-specific DNA binding);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:0000979(RNA polymerase II core promoter sequence-specific DNA binding);GO:0000981(RNA polymerase II transcription factor activity, sequence-specific DNA binding);GO:0001077(transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0003682(chromatin binding);GO:0008134(transcription factor binding);GO:0019900(kinase binding);GO:0035035(histone acetyltransferase binding);GO:0035259(glucocorticoid receptor binding);GO:0042826(histone deacetylase binding);GO:0043565(sequence-specific DNA binding);GO:0044212(transcription regulatory region DNA binding);GO:0044389(ubiquitin-like protein ligase binding);GO:0001889(liver development);GO:0001892(embryonic placenta development);GO:0007613(memory);GO:0030182(neuron differentiation);GO:0032496(response to lipopolysaccharide);GO:0033598(mammary gland epithelial cell proliferation);GO:0043524(negative regulation of neuron apoptotic process);GO:0045408(regulation of interleukin-6 biosynthetic process);GO:0045444(fat cell differentiation);GO:0045669(positive regulation of osteoblast differentiation);GO:0045892(negative regulation of transcription, DNA-templated);GO:0045893(positive regulation of transcription, DNA-templated);GO:0050873(brown fat cell differentiation);GO:0060644(mammary gland epithelial cell differentiation);GO:0060850(regulation of transcription involved in cell fate commitment);GO:0071222(cellular response to lipopolysaccharide);GO:0071230(cellular response to amino acid stimulus);GO:0071347(cellular response to interleukin-1);GO:0071407(cellular response to organic cyclic compound);GO:0072574(hepatocyte proliferation);GO:0097421(liver regeneration);GO:0000779(condensed chromosome, centromeric region);GO:0000790(nuclear chromatin);GO:0016363(nuclear matrix);GO:0036488(CHOP-C/EBP complex)","04668(TNF signaling pathway);04657(IL-17 signaling pathway);05202(Transcriptional misregulation in cancers);05152(Tuberculosis)","K10048","NA","CCAAT/enhancer binding protein beta [Source:HGNC Symbol;Acc:HGNC:1834]",{"v":17.17054,"d":"17.17"},{"v":2.242085,"d":"2.24"},{"v":7.65829127798455,"d":"7.66"},{"v":2.93702253317217,"d":"2.94"},{"v":2.34187356763726e-05,"d":"0.00"},{"v":0.000783291983225811,"d":"0.00"},"up","yes"]
[194332,"j","chr9","-",131576770,131676821,"MSTRG.15057.1",23,6102,"MSTRG.15057","RAPGEF1","NA","NA","NA","NA","NA",{"v":2.56375,"d":"2.56"},{"v":0.330779,"d":"0.33"},{"v":7.75064317867821,"d":"7.75"},{"v":2.95431603583043,"d":"2.95"},{"v":2.35867795928241e-05,"d":"0.00"},{"v":0.000787593335969083,"d":"0.00"},"up","yes"]
[123564,0,"chr20","+",37346154,37406050,"ENST00000373578",14,4630,"ENSG00000197122","SRC","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0005829(cytosol);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0005743(mitochondrial inner membrane);GO:0007155(cell adhesion);GO:0004713(protein tyrosine kinase activity);GO:0005886(plasma membrane);GO:0005739(mitochondrion);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0007049(cell cycle);GO:0004715(non-membrane spanning protein tyrosine kinase activity);GO:0007229(integrin-mediated signaling pathway);GO:0002376(immune system process);GO:0005764(lysosome);GO:0038096(Fc-gamma receptor signaling pathway involved in phagocytosis);GO:0050900(leukocyte migration);GO:0045087(innate immune response);GO:0020037(heme binding);GO:0045453(bone resorption);GO:0005654(nucleoplasm);GO:0045296(cadherin binding);GO:0070062(extracellular exosome);GO:0071902(positive regulation of protein serine/threonine kinase activity);GO:0042169(SH2 domain binding);GO:0002223(stimulatory C-type lectin receptor signaling pathway);GO:0016032(viral process);GO:0005770(late endosome);GO:0005102(receptor binding);GO:0051902(negative regulation of mitochondrial depolarization);GO:0043066(negative regulation of apoptotic process);GO:0044325(ion channel binding);GO:0007165(signal transduction);GO:0019899(enzyme binding);GO:0042127(regulation of cell proliferation);GO:0030168(platelet activation);GO:0007411(axon guidance);GO:0048013(ephrin receptor signaling pathway);GO:0046777(protein autophosphorylation);GO:0048010(vascular endothelial growth factor receptor signaling pathway);GO:0007179(transforming growth factor beta receptor signaling pathway);GO:0043154(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process);GO:2001243(negative regulation of intrinsic apoptotic signaling pathway);GO:0005070(SH3/SH2 adaptor activity);GO:0038128(ERBB2 signaling pathway);GO:0097110(scaffold protein binding);GO:0007417(central nervous system development);GO:0035556(intracellular signal transduction);GO:0051897(positive regulation of protein kinase B signaling);GO:0032463(negative regulation of protein homooligomerization);GO:0070851(growth factor receptor binding);GO:0007173(epidermal growth factor receptor signaling pathway);GO:0051219(phosphoprotein binding);GO:2001237(negative regulation of extrinsic apoptotic signaling pathway);GO:0010634(positive regulation of epithelial cell migration);GO:0050731(positive regulation of peptidyl-tyrosine phosphorylation);GO:0031295(T cell costimulation);GO:0019900(kinase binding);GO:0051895(negative regulation of focal adhesion assembly);GO:0070555(response to interleukin-1);GO:0016236(macroautophagy);GO:0033625(positive regulation of integrin activation);GO:0038083(peptidyl-tyrosine autophosphorylation);GO:0005901(caveola);GO:0031234(extrinsic component of cytoplasmic side of plasma membrane);GO:0035635(entry of bacterium into host cell);GO:2000641(regulation of early endosome to late endosome transport);GO:0051726(regulation of cell cycle);GO:0008022(protein C-terminus binding);GO:0005178(integrin binding);GO:0051974(negative regulation of telomerase activity);GO:0045124(regulation of bone resorption);GO:2000811(negative regulation of anoikis);GO:0018108(peptidyl-tyrosine phosphorylation);GO:0046875(ephrin receptor binding);GO:0007172(signal complex assembly);GO:0032211(negative regulation of telomere maintenance via telomerase);GO:0043114(regulation of vascular permeability);GO:2000394(positive regulation of lamellipodium morphogenesis);GO:0005080(protein kinase C binding);GO:0005158(insulin receptor binding);GO:0019901(protein kinase binding);GO:0019904(protein domain specific binding);GO:0030331(estrogen receptor binding);GO:0031625(ubiquitin protein ligase binding);GO:0032403(protein complex binding);GO:0050839(cell adhesion molecule binding);GO:0051427(hormone receptor binding);GO:0071253(connexin binding);GO:0008283(cell proliferation);GO:0009612(response to mechanical stimulus);GO:0009615(response to virus);GO:0010447(response to acidic pH);GO:0010628(positive regulation of gene expression);GO:0010632(regulation of epithelial cell migration);GO:0010641(positive regulation of platelet-derived growth factor receptor signaling pathway);GO:0010907(positive regulation of glucose metabolic process);GO:0010954(positive regulation of protein processing);GO:0014911(positive regulation of smooth muscle cell migration);GO:0016337(single organismal cell-cell adhesion);GO:0016477(cell migration);GO:0018105(peptidyl-serine phosphorylation);GO:0022407(regulation of cell-cell adhesion);GO:0030520(intracellular estrogen receptor signaling pathway);GO:0030900(forebrain development);GO:0031648(protein destabilization);GO:0031667(response to nutrient levels);GO:0031954(positive regulation of protein autophosphorylation);GO:0032148(activation of protein kinase B activity);GO:0032869(cellular response to insulin stimulus);GO:0033146(regulation of intracellular estrogen receptor signaling pathway);GO:0034332(adherens junction organization);GO:0034446(substrate adhesion-dependent cell spreading);GO:0034614(cellular response to reactive oxygen species);GO:0036035(osteoclast development);GO:0036120(cellular response to platelet-derived growth factor stimulus);GO:0042493(response to drug);GO:0042542(response to hydrogen peroxide);GO:0043065(positive regulation of apoptotic process);GO:0043149(stress fiber assembly);GO:0043393(regulation of protein binding);GO:0043406(positive regulation of MAP kinase activity);GO:0043552(positive regulation of phosphatidylinositol 3-kinase activity);GO:0045056(transcytosis);GO:0045737(positive regulation of cyclin-dependent protein serine/threonine kinase activity);GO:0045785(positive regulation of cell adhesion);GO:0045892(negative regulation of transcription, DNA-templated);GO:0045893(positive regulation of transcription, DNA-templated);GO:0046628(positive regulation of insulin receptor signaling pathway);GO:0048008(platelet-derived growth factor receptor signaling pathway);GO:0048011(neurotrophin TRK receptor signaling pathway);GO:0048477(oogenesis);GO:0050715(positive regulation of cytokine secretion);GO:0050847(progesterone receptor signaling pathway);GO:0051057(positive regulation of small GTPase mediated signal transduction);GO:0051222(positive regulation of protein transport);GO:0051385(response to mineralocorticoid);GO:0051602(response to electrical stimulus);GO:0060065(uterus development);GO:0060444(branching involved in mammary gland duct morphogenesis);GO:0060491(regulation of cell projection assembly);GO:0070374(positive regulation of ERK1 and ERK2 cascade);GO:0070542(response to fatty acid);GO:0071222(cellular response to lipopolysaccharide);GO:0071375(cellular response to peptide hormone stimulus);GO:0071393(cellular response to progesterone stimulus);GO:0071398(cellular response to fatty acid);GO:0071456(cellular response to hypoxia);GO:0071498(cellular response to fluid shear stress);GO:0071560(cellular response to transforming growth factor beta stimulus);GO:0071801(regulation of podosome assembly);GO:0071803(positive regulation of podosome assembly);GO:0086098(angiotensin-activated signaling pathway involved in heart process);GO:0090263(positive regulation of canonical Wnt signaling pathway);GO:1900182(positive regulation of protein localization to nucleus);GO:1902533(positive regulation of intracellular signal transduction);GO:2000573(positive regulation of DNA biosynthetic process);GO:2001286(regulation of caveolin-mediated endocytosis);GO:0002102(podosome);GO:0005884(actin filament);GO:0014069(postsynaptic density);GO:0032587(ruffle membrane);GO:0043005(neuron projection);GO:0048471(perinuclear region of cytoplasm)","04015(Rap1 signaling pathway);04012(ErbB signaling pathway);04370(VEGF signaling pathway);04144(Endocytosis);04137(Mitophagy - animal);04510(Focal adhesion);04520(Adherens junction);04530(Tight junction);04540(Gap junction);04810(Regulation of actin cytoskeleton);04611(Platelet activation);04062(Chemokine signaling pathway);04912(GnRH signaling pathway);04915(Estrogen signaling pathway);04917(Prolactin signaling pathway);04921(Oxytocin signaling pathway);04926(Relaxin signaling pathway);04919(Thyroid hormone signaling pathway);04727(GABAergic synapse);04750(Inflammatory mediator regulation of TRP channels);04360(Axon guidance);05205(Proteoglycans in cancer);05203(Viral carcinogenesis);05219(Bladder cancer);05418(Fluid shear stress and atherosclerosis);05120(Epithelial cell signaling in Helicobacter pylori infection);05131(Shigellosis);05152(Tuberculosis);05100(Bacterial invasion of epithelial cells);05161(Hepatitis B);05167(Kaposi's sarcoma-associated herpesvirus infection);01521(EGFR tyrosine kinase inhibitor resistance);01522(Endocrine resistance)","K05704","EC:2.7.10.2","SRC proto-oncogene, non-receptor tyrosine kinase [Source:HGNC Symbol;Acc:HGNC:11283]",{"v":0.52907,"d":"0.53"},{"v":4.432365,"d":"4.43"},{"v":0.119365169610355,"d":"0.12"},{"v":-3.0665461708562,"d":"-3.07"},{"v":2.3779792229215E-5,"d":"0.00"},{"v":0.000792712673176902,"d":"0.00"},"down","yes"]
[85703,0,"chr17","-",50962174,51120865,"ENST00000262013",30,8273,"MSTRG.7030","SPAG9","GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005515(protein binding);GO:0048471(perinuclear region of cytoplasm);GO:0005815(microtubule organizing center);GO:0031410(cytoplasmic vesicle);GO:0070062(extracellular exosome);GO:0030335(positive regulation of cell migration);GO:0001669(acrosomal vesicle);GO:0016021(integral component of membrane);GO:0007283(spermatogenesis);GO:0007257(activation of JUN kinase activity);GO:0005078(MAP-kinase scaffold activity);GO:0008432(JUN kinase binding);GO:0019894(kinesin binding);GO:0030159(receptor signaling complex scaffold activity);GO:0048273(mitogen-activated protein kinase p38 binding);GO:0000187(activation of MAPK activity);GO:0042147(retrograde transport, endosome to Golgi);GO:0043410(positive regulation of MAPK cascade);GO:0045666(positive regulation of neuron differentiation);GO:0051146(striated muscle cell differentiation);GO:0051149(positive regulation of muscle cell differentiation);GO:0051260(protein homooligomerization);GO:0090074(negative regulation of protein homodimerization activity);GO:0016020(membrane)","NA","NA","NA","sperm associated antigen 9 [Source:HGNC Symbol;Acc:HGNC:14524]",{"v":2.94363,"d":"2.94"},{"v":0.382084,"d":"0.38"},{"v":7.70414359146156,"d":"7.70"},{"v":2.94563459268799,"d":"2.95"},{"v":2.40041993882979e-05,"d":"0.00"},{"v":0.000798859755642553,"d":"0.00"},"up","yes"]
[54899,0,"chr14","-",50725827,50830479,"ENST00000382043",28,4216,"MSTRG.4381","NIN","GO:0005509(calcium ion binding);GO:0005813(centrosome);GO:0034454(microtubule anchoring at centrosome);GO:0005737(cytoplasm);GO:0000166(nucleotide binding);GO:0005634(nucleus);GO:0005730(nucleolus);GO:0005525(GTP binding);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0005874(microtubule);GO:0005815(microtubule organizing center);GO:0005814(centriole);GO:0097539(ciliary transition fiber);GO:0000922(spindle pole);GO:0000242(pericentriolar material);GO:0051642(centrosome localization);GO:0090222(centrosome-templated microtubule nucleation);GO:0036449(microtubule minus-end);GO:0097431(mitotic spindle pole)","NA","NA","NA","ninein [Source:HGNC Symbol;Acc:HGNC:14906]",{"v":1.318162,"d":"1.32"},{"v":0.161089,"d":"0.16"},{"v":8.18281819366934,"d":"8.18"},{"v":3.03259779840091,"d":"3.03"},{"v":2.40507314853515E-5,"d":"0.00"},{"v":0.000799076549583193,"d":"0.00"},"up","yes"]
[46604,"j","chr12","-",110491894,110502118,"MSTRG.3717.9",6,779,"MSTRG.3717","VPS29","NA","NA","NA","NA","NA",{"v":2.452824,"d":"2.45"},{"v":20.684227,"d":"20.68"},{"v":0.118584271967234,"d":"0.12"},{"v":-3.07601541940113,"d":"-3.08"},{"v":2.4482172158874E-5,"d":"0.00"},{"v":0.000811329167560849,"d":"0.00"},"down","yes"]
[171513,0,"chr7","+",5190196,5231524,"ENST00000401525",12,2112,"MSTRG.13466","WIPI2","GO:0016020(membrane);GO:0006914(autophagy);GO:0005829(cytosol);GO:0005515(protein binding);GO:0032266(phosphatidylinositol-3-phosphate binding);GO:0080025(phosphatidylinositol-3,5-bisphosphate binding);GO:0000045(autophagosome assembly);GO:0034497(protein localization to pre-autophagosomal structure);GO:0061739(protein lipidation involved in autophagosome assembly);GO:0098792(xenophagy);GO:0000407(pre-autophagosomal structure);GO:0005776(autophagosome);GO:0034045(pre-autophagosomal structure membrane);GO:0000422(mitophagy);GO:0006497(protein lipidation);GO:0044804(nucleophagy);GO:0019898(extrinsic component of membrane);GO:0016236(macroautophagy);GO:0043234(protein complex)","04140(Autophagy - animal);04136(Autophagy - other eukaryotes)","K17908","NA","WD repeat domain, phosphoinositide interacting 2 [Source:HGNC Symbol;Acc:HGNC:32225]",{"v":6.057586,"d":"6.06"},{"v":0.777303,"d":"0.78"},{"v":7.79308197704113,"d":"7.79"},{"v":2.96219399242872,"d":"2.96"},{"v":2.45172604359774e-05,"d":"0.00"},{"v":0.000811329167560849,"d":"0.00"},"up","yes"]
[61395,0,"chr15","-",41517176,41544259,"ENST00000304330",25,4665,"ENSG00000103932","RPAP1","GO:0005634(nucleus);GO:0016740(transferase activity);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0016779(nucleotidyltransferase activity);GO:0003899(DNA-directed 5'-3' RNA polymerase activity);GO:0006366(transcription from RNA polymerase II promoter)","NA","NA","NA","RNA polymerase II associated protein 1 [Source:HGNC Symbol;Acc:HGNC:24567]",{"v":0.177895,"d":"0.18"},{"v":1.568953,"d":"1.57"},{"v":0.113384530957906,"d":"0.11"},{"v":-3.14070426794591,"d":"-3.14"},{"v":2.45414071117164E-5,"d":"0.00"},{"v":0.000811329167560849,"d":"0.00"},"down","yes"]
[94092,0,"chr19","+",1026610,1039068,"ENST00000348419",6,2033,"MSTRG.7591","CNN2","GO:0016020(membrane);GO:0003779(actin binding);GO:0005856(cytoskeleton);GO:0005925(focal adhesion);GO:0005576(extracellular region);GO:0007010(cytoskeleton organization);GO:0005516(calmodulin binding);GO:0031032(actomyosin structure organization);GO:0045296(cadherin binding);GO:0070062(extracellular exosome);GO:0043312(neutrophil degranulation);GO:0035722(interleukin-12-mediated signaling pathway);GO:0035580(specific granule lumen);GO:1904724(tertiary granule lumen);GO:0005911(cell-cell junction);GO:0001725(stress fiber);GO:0032970(regulation of actin filament-based process);GO:0071260(cellular response to mechanical stimulus);GO:0010628(positive regulation of gene expression);GO:0030097(hemopoiesis);GO:0030336(negative regulation of cell migration);GO:0042060(wound healing);GO:0042127(regulation of cell proliferation);GO:0050765(negative regulation of phagocytosis)","NA","NA","NA","calponin 2 [Source:HGNC Symbol;Acc:HGNC:2156]",{"v":1.023091,"d":"1.02"},{"v":8.576936,"d":"8.58"},{"v":0.11928397273805,"d":"0.12"},{"v":-3.06752788257222,"d":"-3.07"},{"v":2.48262026890637E-5,"d":"0.00"},{"v":0.000819387793876404,"d":"0.00"},"down","yes"]
[190151,0,"chr9","+",36136742,36162910,"ENST00000377959",4,812,"MSTRG.14756","GLIPR2","GO:0005576(extracellular region);GO:0016020(membrane);GO:0005794(Golgi apparatus);GO:0042803(protein homodimerization activity);GO:0000139(Golgi membrane);GO:0070062(extracellular exosome);GO:0070374(positive regulation of ERK1 and ERK2 cascade);GO:0010718(positive regulation of epithelial to mesenchymal transition);GO:0010634(positive regulation of epithelial cell migration)","NA","NA","NA","GLI pathogenesis related 2 [Source:HGNC Symbol;Acc:HGNC:18007]",{"v":4.360395,"d":"4.36"},{"v":36.036602,"d":"36.04"},{"v":0.120999060899249,"d":"0.12"},{"v":-3.04693224442265,"d":"-3.05"},{"v":2.50068439578473E-5,"d":"0.00"},{"v":0.000823987888036789,"d":"0.00"},"down","yes"]
[63939,"j","chr15","+",68054179,68198685,"MSTRG.5242.1",15,8967,"MSTRG.5242","PIAS1","NA","NA","NA","NA","NA",{"v":1.698529,"d":"1.70"},{"v":0.219622,"d":"0.22"},{"v":7.73387456630028,"d":"7.73"},{"v":2.9511913659149,"d":"2.95"},{"v":2.53038022268781e-05,"d":"0.00"},{"v":0.00083239921394778,"d":"0.00"},"up","yes"]
[55066,0,"chr14","+",52730180,52774941,"ENST00000442123",12,4554,"MSTRG.4399","STYX","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005654(nucleoplasm);GO:0016787(hydrolase activity);GO:0008138(protein tyrosine/serine/threonine phosphatase activity);GO:0016791(phosphatase activity);GO:0006470(protein dephosphorylation);GO:0016311(dephosphorylation);GO:0005829(cytosol);GO:0004721(phosphoprotein phosphatase activity);GO:0005515(protein binding);GO:0070372(regulation of ERK1 and ERK2 cascade);GO:0007283(spermatogenesis);GO:0045204(MAPK export from nucleus)","NA","NA","NA","serine/threonine/tyrosine interacting protein [Source:HGNC Symbol;Acc:HGNC:11447]",{"v":1.88278,"d":"1.88"},{"v":0.23548,"d":"0.24"},{"v":7.99549855614065,"d":"8.00"},{"v":2.99918799518735,"d":"3.00"},{"v":2.53513076995783e-05,"d":"0.00"},{"v":8.32590316028256E-4,"d":"0.00"},"up","yes"]
[49085,0,"chr13","-",23328826,23411513,"ENST00000382292",9,15324,"ENSG00000151835","SACS","GO:0005737(cytoplasm);GO:0005634(nucleus);GO:0006457(protein folding);GO:0051087(chaperone binding);GO:0030424(axon);GO:0030544(Hsp70 protein binding);GO:0005739(mitochondrion);GO:0030425(dendrite);GO:0090084(negative regulation of inclusion body assembly);GO:0070852(cell body fiber);GO:0070628(proteasome binding)","NA","NA","NA","sacsin molecular chaperone [Source:HGNC Symbol;Acc:HGNC:10519]",{"v":0.085735,"d":"0.09"},{"v":0.731475,"d":"0.73"},{"v":0.117208380327421,"d":"0.12"},{"v":-3.09285236962739,"d":"-3.09"},{"v":2.57788848718977e-05,"d":"0.00"},{"v":0.000845242648804687,"d":"0.00"},"down","yes"]
[68923,0,"chr16","+",3642938,3665472,"ENST00000407479",10,8552,"MSTRG.5586","DNASE1","GO:0004536(deoxyribonuclease activity);GO:0006308(DNA catabolic process);GO:0005634(nucleus);GO:0016787(hydrolase activity);GO:0003779(actin binding);GO:0090305(nucleic acid phosphodiester bond hydrolysis);GO:0005576(extracellular region);GO:0006915(apoptotic process);GO:0004519(endonuclease activity);GO:0004518(nuclease activity);GO:0005515(protein binding);GO:0070062(extracellular exosome);GO:0005635(nuclear envelope);GO:0004530(deoxyribonuclease I activity)","NA","NA","NA","deoxyribonuclease 1 [Source:HGNC Symbol;Acc:HGNC:2956]",{"v":0.072699,"d":"0.07"},{"v":0.647459,"d":"0.65"},{"v":0.112283557723346,"d":"0.11"},{"v":-3.1547814131659,"d":"-3.15"},{"v":2.59273552563944e-05,"d":"0.00"},{"v":0.000848717097966693,"d":"0.00"},"down","yes"]
[85138,0,"chr17","+",48831035,48863174,"ENST00000416445",12,1438,"MSTRG.6982","CALCOCO2","GO:0048471(perinuclear region of cytoplasm);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0043231(intracellular membrane-bounded organelle);GO:0005829(cytosol);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0006914(autophagy);GO:0031410(cytoplasmic vesicle);GO:0000421(autophagosome membrane);GO:0042803(protein homodimerization activity);GO:0005634(nucleus);GO:0098792(xenophagy);GO:0034341(response to interferon-gamma);GO:0005776(autophagosome);GO:1901098(positive regulation of autophagosome maturation);GO:0016032(viral process)","04137(Mitophagy - animal)","K21348","NA","calcium binding and coiled-coil domain 2 [Source:HGNC Symbol;Acc:HGNC:29912]",{"v":7.858213,"d":"7.86"},{"v":1.011393,"d":"1.01"},{"v":7.76969288891657,"d":"7.77"},{"v":2.95785757464412,"d":"2.96"},{"v":2.6129007382175E-5,"d":"0.00"},{"v":0.000853918198702571,"d":"0.00"},"up","yes"]
[72010,0,"chr16","+",30699141,30741409,"ENST00000262518",34,11754,"MSTRG.5867","SRCAP","GO:0005634(nucleus);GO:0005794(Golgi apparatus);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0005654(nucleoplasm);GO:0016787(hydrolase activity);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0016569(covalent chromatin modification);GO:0003677(DNA binding);GO:0004386(helicase activity);GO:0016604(nuclear body);GO:0016573(histone acetylation);GO:0048471(perinuclear region of cytoplasm);GO:0043234(protein complex);GO:0016032(viral process);GO:0005515(protein binding);GO:0003713(transcription coactivator activity);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0004402(histone acetyltransferase activity)","NA","NA","NA","Snf2 related CREBBP activator protein [Source:HGNC Symbol;Acc:HGNC:16974]",{"v":0.337281,"d":"0.34"},{"v":2.765603,"d":"2.77"},{"v":0.121955681997742,"d":"0.12"},{"v":-3.03557111904929,"d":"-3.04"},{"v":2.64559194014435E-5,"d":"0.00"},{"v":0.000863189213411803,"d":"0.00"},"down","yes"]
[3224,0,"chr1","+",27234516,27308633,"ENST00000319394",16,4819,"MSTRG.293","WDTC1","GO:0016567(protein ubiquitination);GO:0043086(negative regulation of catalytic activity);GO:0005654(nucleoplasm);GO:0043687(post-translational protein modification);GO:0005515(protein binding);GO:0004857(enzyme inhibitor activity);GO:0042393(histone binding);GO:0042826(histone deacetylase binding);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0001701(in utero embryonic development);GO:0006006(glucose metabolic process);GO:0008361(regulation of cell size);GO:0032869(cellular response to insulin stimulus);GO:0035264(multicellular organism growth);GO:0045717(negative regulation of fatty acid biosynthetic process);GO:0055082(cellular chemical homeostasis);GO:0005634(nucleus);GO:0005829(cytosol)","NA","NA","NA","WD and tetratricopeptide repeats 1 [Source:HGNC Symbol;Acc:HGNC:29175]",{"v":1.795759,"d":"1.80"},{"v":14.577209,"d":"14.58"},{"v":0.123189493955942,"d":"0.12"},{"v":-3.02104887184129,"d":"-3.02"},{"v":2.65549774530219E-5,"d":"0.00"},{"v":0.00086500781367364,"d":"0.00"},"down","yes"]
[111112,0,"chr2","+",73829020,73867172,"ENST00000394070",10,6691,"ENSG00000124356","STAMBP","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0046872(metal ion binding);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0016787(hydrolase activity);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0008233(peptidase activity);GO:0006508(proteolysis);GO:0008237(metallopeptidase activity);GO:0005768(endosome);GO:0070062(extracellular exosome);GO:0016579(protein deubiquitination);GO:0005769(early endosome);GO:0019904(protein domain specific binding);GO:0007259(JAK-STAT cascade);GO:0014067(negative regulation of phosphatidylinositol 3-kinase signaling);GO:0008284(positive regulation of cell proliferation);GO:0046580(negative regulation of Ras protein signal transduction);GO:0004843(thiol-dependent ubiquitin-specific protease activity);GO:0000281(mitotic cytokinesis);GO:0032154(cleavage furrow);GO:0043524(negative regulation of neuron apoptotic process)","04144(Endocytosis)","K11866","EC:3.4.19.12","STAM binding protein [Source:HGNC Symbol;Acc:HGNC:16950]",{"v":1.986815,"d":"1.99"},{"v":0.258133,"d":"0.26"},{"v":7.69686556929955,"d":"7.70"},{"v":2.94427104992886,"d":"2.94"},{"v":2.68130598937083e-05,"d":"0.00"},{"v":0.000871992149768025,"d":"0.00"},"up","yes"]
[30858,0,"chr11","-",64764606,64778786,"ENST00000334944",14,3094,"MSTRG.2520","SF1","GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0006397(mRNA processing);GO:0008380(RNA splicing);GO:0005634(nucleus);GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0005654(nucleoplasm);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0005840(ribosome);GO:0005515(protein binding);GO:0005681(spliceosomal complex);GO:0045131(pre-mRNA branch point binding);GO:0000398(mRNA splicing, via spliceosome);GO:1903507(negative regulation of nucleic acid-templated transcription);GO:0042802(identical protein binding);GO:0003714(transcription corepressor activity);GO:0000245(spliceosomal complex assembly);GO:0000389(mRNA 3'-splice site recognition);GO:0030238(male sex determination);GO:0030575(nuclear body organization);GO:0033327(Leydig cell differentiation);GO:0048662(negative regulation of smooth muscle cell proliferation);GO:0050810(regulation of steroid biosynthetic process);GO:0016604(nuclear body)","NA","NA","NA","splicing factor 1 [Source:HGNC Symbol;Acc:HGNC:12950]",{"v":3.431389,"d":"3.43"},{"v":0.440651,"d":"0.44"},{"v":7.78709001000792,"d":"7.79"},{"v":2.96108430229727,"d":"2.96"},{"v":2.69929828641445e-05,"d":"0.00"},{"v":0.000876416068018272,"d":"0.00"},"up","yes"]
[112129,"j","chr2","-",88857161,89100347,"MSTRG.8934.26",4,924,"MSTRG.8934","IGKV1-16","NA","NA","NA","NA","NA",{"v":9.478786,"d":"9.48"},{"v":1.213954,"d":"1.21"},{"v":7.80819207317575,"d":"7.81"},{"v":2.96498854209264,"d":"2.96"},{"v":2.77101234583497e-05,"d":"0.00"},{"v":0.000898239846130399,"d":"0.00"},"up","yes"]
[133109,0,"chr3","+",9793082,9806436,"ENST00000417500",7,957,"MSTRG.10649","ARPC4","GO:0005737(cytoplasm);GO:0003779(actin binding);GO:0015629(actin cytoskeleton);GO:0005856(cytoskeleton);GO:0042995(cell projection);GO:0005515(protein binding);GO:0030041(actin filament polymerization);GO:0030833(regulation of actin filament polymerization);GO:0034314(Arp2/3 complex-mediated actin nucleation);GO:0005885(Arp2/3 protein complex);GO:0038096(Fc-gamma receptor signaling pathway involved in phagocytosis);GO:0005829(cytosol);GO:0051015(actin filament binding);GO:0070062(extracellular exosome);GO:0061024(membrane organization);GO:0030674(protein binding, bridging);GO:0048013(ephrin receptor signaling pathway);GO:0019899(enzyme binding);GO:0005200(structural constituent of cytoskeleton);GO:0045010(actin nucleation)","04144(Endocytosis);04810(Regulation of actin cytoskeleton);04666(Fc gamma R-mediated phagocytosis);05130(Pathogenic Escherichia coli infection);05132(Salmonella infection);05131(Shigellosis);05100(Bacterial invasion of epithelial cells)","NA","NA","actin related protein 2/3 complex subunit 4 [Source:HGNC Symbol;Acc:HGNC:707]",{"v":0.892639,"d":"0.89"},{"v":7.7123,"d":"7.71"},{"v":0.115742255876976,"d":"0.12"},{"v":-3.1110124265132,"d":"-3.11"},{"v":2.78352110149699e-05,"d":"0.00"},{"v":0.000900832242377502,"d":"0.00"},"down","yes"]
[25604,0,"chr11","-",3675010,3797792,"ENST00000324932",33,6973,"MSTRG.2149","NUP98","GO:0006810(transport);GO:0051028(mRNA transport);GO:0005634(nucleus);GO:0016020(membrane);GO:0015031(protein transport);GO:0043231(intracellular membrane-bounded organelle);GO:0005654(nucleoplasm);GO:0016787(hydrolase activity);GO:0030529(intracellular ribonucleoprotein complex);GO:0005643(nuclear pore);GO:0008233(peptidase activity);GO:0006508(proteolysis);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0006260(DNA replication);GO:0008236(serine-type peptidase activity);GO:0000776(kinetochore);GO:0003729(mRNA binding);GO:0003723(RNA binding);GO:0005515(protein binding);GO:0005829(cytosol);GO:0075733(intracellular transport of virus);GO:0043657(host cell);GO:0016032(viral process);GO:0008139(nuclear localization sequence binding);GO:0007062(sister chromatid cohesion);GO:0031965(nuclear membrane);GO:0005215(transporter activity);GO:0005635(nuclear envelope);GO:0006406(mRNA export from nucleus);GO:0001105(RNA polymerase II transcription coactivator activity);GO:0016925(protein sumoylation);GO:0006606(protein import into nucleus);GO:0060964(regulation of gene silencing by miRNA);GO:0006110(regulation of glycolytic process);GO:0006409(tRNA export from nucleus);GO:0007077(mitotic nuclear envelope disassembly);GO:0019083(viral transcription);GO:1900034(regulation of cellular response to heat);GO:1990841(promoter-specific chromatin binding);GO:0006913(nucleocytoplasmic transport);GO:0016604(nuclear body);GO:0042405(nuclear inclusion body);GO:0006405(RNA export from nucleus);GO:0034399(nuclear periphery);GO:0006999(nuclear pore organization);GO:0044615(nuclear pore nuclear basket);GO:0048026(positive regulation of mRNA splicing, via spliceosome);GO:0005487(nucleocytoplasmic transporter activity);GO:0017056(structural constituent of nuclear pore);GO:0051292(nuclear pore complex assembly);GO:0044614(nuclear pore cytoplasmic filaments);GO:0042277(peptide binding);GO:0000973(posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery);GO:0034398(telomere tethering at nuclear periphery);GO:0031080(nuclear pore outer ring)","03013(RNA transport);05164(Influenza A)","K14297","NA","nucleoporin 98 [Source:HGNC Symbol;Acc:HGNC:8068]",{"v":1.351456,"d":"1.35"},{"v":10.89564,"d":"10.90"},{"v":0.124036403552247,"d":"0.12"},{"v":-3.01116449430274,"d":"-3.01"},{"v":2.78862762935731E-5,"d":"0.00"},{"v":0.000901024538883606,"d":"0.00"},"down","yes"]
[105526,"j","chr19","+",54449103,54462037,"MSTRG.8421.3",15,6015,"MSTRG.8421","LENG8","NA","NA","NA","NA","NA",{"v":0.329829,"d":"0.33"},{"v":2.721234,"d":"2.72"},{"v":0.121205673602491,"d":"0.12"},{"v":-3.04447086235869,"d":"-3.04"},{"v":2.85357082543524E-5,"d":"0.00"},{"v":9.20518614576589E-4,"d":"0.00"},"down","yes"]
[15572,0,"chr1","+",207752057,207795513,"ENST00000357714",11,3188,"MSTRG.1363","CD46","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0043086(negative regulation of catalytic activity);GO:0031410(cytoplasmic vesicle);GO:0009986(cell surface);GO:0002376(immune system process);GO:0045087(innate immune response);GO:0005925(focal adhesion);GO:0002250(adaptive immune response);GO:0030449(regulation of complement activation);GO:0046718(viral entry into host cell);GO:0070062(extracellular exosome);GO:0010628(positive regulation of gene expression);GO:0042102(positive regulation of T cell proliferation);GO:0007338(single fertilization);GO:0016032(viral process);GO:0005887(integral component of plasma membrane);GO:0002456(T cell mediated immunity);GO:0010629(negative regulation of gene expression);GO:0071636(positive regulation of transforming growth factor beta production);GO:0006958(complement activation, classical pathway);GO:0004872(receptor activity);GO:0045296(cadherin binding);GO:0001618(virus receptor activity);GO:0032733(positive regulation of interleukin-10 production);GO:0008593(regulation of Notch signaling pathway);GO:0032613(interleukin-10 production);GO:0035581(sequestering of extracellular ligand from receptor);GO:0043382(positive regulation of memory T cell differentiation);GO:0045591(positive regulation of regulatory T cell differentiation);GO:0002079(inner acrosomal membrane);GO:0001848(complement binding);GO:0004175(endopeptidase activity);GO:0004857(enzyme inhibitor activity);GO:0006508(proteolysis);GO:0045916(negative regulation of complement activation);GO:0001669(acrosomal vesicle);GO:0005737(cytoplasm);GO:0005794(Golgi apparatus);GO:0016323(basolateral plasma membrane)","04610(Complement and coagulation cascades);05162(Measles)","K04007","NA","CD46 molecule [Source:HGNC Symbol;Acc:HGNC:6953]",{"v":0.389961,"d":"0.39"},{"v":3.257704,"d":"3.26"},{"v":0.119704245689602,"d":"0.12"},{"v":-3.06245377195676,"d":"-3.06"},{"v":2.87179375607359e-05,"d":"0.00"},{"v":0.000924902866472216,"d":"0.00"},"down","yes"]
[175241,0,"chr7","+",75915164,75986855,"ENST00000394893",15,2532,"MSTRG.13735","POR","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005515(protein binding);GO:0010181(FMN binding);GO:0043231(intracellular membrane-bounded organelle);GO:0006805(xenobiotic metabolic process);GO:0003958(NADPH-hemoprotein reductase activity);GO:0032770(positive regulation of monooxygenase activity);GO:0090346(cellular organofluorine metabolic process);GO:0004128(cytochrome-b5 reductase activity, acting on NAD(P)H);GO:0008941(nitric oxide dioxygenase activity);GO:0009055(electron carrier activity);GO:0016787(hydrolase activity);GO:0019899(enzyme binding);GO:0047726(iron-cytochrome-c reductase activity);GO:0050660(flavin adenine dinucleotide binding);GO:0050661(NADP binding);GO:0003420(regulation of growth plate cartilage chondrocyte proliferation);GO:0007584(response to nutrient);GO:0009437(carnitine metabolic process);GO:0009812(flavonoid metabolic process);GO:0018393(internal peptidyl-lysine acetylation);GO:0019395(fatty acid oxidation);GO:0032332(positive regulation of chondrocyte differentiation);GO:0042493(response to drug);GO:0043066(negative regulation of apoptotic process);GO:0043154(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process);GO:0043602(nitrate catabolic process);GO:0045542(positive regulation of cholesterol biosynthetic process);GO:0045880(positive regulation of smoothened signaling pathway);GO:0046210(nitric oxide catabolic process);GO:0060192(negative regulation of lipase activity);GO:0070988(demethylation);GO:0071371(cellular response to gonadotropin stimulus);GO:0071372(cellular response to follicle-stimulating hormone stimulus);GO:0071375(cellular response to peptide hormone stimulus);GO:0090031(positive regulation of steroid hormone biosynthetic process);GO:0090181(regulation of cholesterol metabolic process);GO:0005739(mitochondrion)","NA","NA","NA","cytochrome p450 oxidoreductase [Source:HGNC Symbol;Acc:HGNC:9208]",{"v":3.614867,"d":"3.61"},{"v":0.466663,"d":"0.47"},{"v":7.74620443446341,"d":"7.75"},{"v":2.95348957684968,"d":"2.95"},{"v":2.90114099974461E-5,"d":"0.00"},{"v":0.000932849975570053,"d":"0.00"},"up","yes"]
[173790,0,"chr7","+",45027026,45076451,"ENST00000475551",10,2471,"MSTRG.13636","CCM2","GO:0005737(cytoplasm);GO:0005739(mitochondrion);GO:0005515(protein binding);GO:0007275(multicellular organism development);GO:0007229(integrin-mediated signaling pathway);GO:0051403(stress-activated MAPK cascade);GO:0001570(vasculogenesis);GO:0061154(endothelial tube morphogenesis);GO:0001568(blood vessel development);GO:0001701(in utero embryonic development);GO:0001885(endothelial cell development);GO:0001944(vasculature development);GO:0007507(heart development);GO:0035264(multicellular organism growth);GO:0045216(cell-cell junction organization);GO:0048839(inner ear development);GO:0048845(venous blood vessel morphogenesis);GO:0060039(pericardium development);GO:0060837(blood vessel endothelial cell differentiation);GO:0043234(protein complex)","NA","NA","NA","CCM2 scaffolding protein [Source:HGNC Symbol;Acc:HGNC:21708]",{"v":5.069071,"d":"5.07"},{"v":0.663303,"d":"0.66"},{"v":7.64216504372813,"d":"7.64"},{"v":2.93398141514072,"d":"2.93"},{"v":2.90739820177597E-5,"d":"0.00"},{"v":0.00093335895969554,"d":"0.00"},"up","yes"]
[139635,0,"chr3","-",121663203,121749740,"ENST00000393667",22,11198,"ENSG00000173230","GOLGB1","GO:0003723(RNA binding);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005794(Golgi apparatus);GO:0006355(regulation of transcription, DNA-templated);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0043565(sequence-specific DNA binding);GO:0005515(protein binding);GO:0000139(Golgi membrane);GO:0006888(ER to Golgi vesicle-mediated transport);GO:0005793(endoplasmic reticulum-Golgi intermediate compartment);GO:0005795(Golgi stack);GO:0007030(Golgi organization);GO:1905793(protein localization to pericentriolar material);GO:0005801(cis-Golgi network)","NA","NA","NA","golgin B1 [Source:HGNC Symbol;Acc:HGNC:4429]",{"v":3.360154,"d":"3.36"},{"v":0.451708,"d":"0.45"},{"v":7.43877460660427,"d":"7.44"},{"v":2.89506498496527,"d":"2.90"},{"v":2.93438948029653e-05,"d":"0.00"},{"v":0.000940511864246568,"d":"0.00"},"up","yes"]
[93216,0,"chr18","+",63969925,63989374,"ENST00000397985",7,3477,"ENSG00000166401","SERPINB8","GO:0005737(cytoplasm);GO:0005615(extracellular space);GO:0005829(cytosol);GO:0030414(peptidase inhibitor activity);GO:0010466(negative regulation of peptidase activity);GO:0005515(protein binding);GO:0070062(extracellular exosome);GO:0004867(serine-type endopeptidase inhibitor activity);GO:0010951(negative regulation of endopeptidase activity);GO:0090136(epithelial cell-cell adhesion)","NA","NA","NA","serpin family B member 8 [Source:HGNC Symbol;Acc:HGNC:8952]",{"v":0.380259,"d":"0.38"},{"v":3.161466,"d":"3.16"},{"v":0.120279326110102,"d":"0.12"},{"v":-3.05553940483868,"d":"-3.06"},{"v":2.99238788671542e-05,"d":"0.00"},{"v":9.56292107915897E-4,"d":"0.00"},"down","yes"]
[66436,0,"chr15","+",90529925,90645345,"ENST00000420329",15,5209,"MSTRG.5428","CRTC3","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0051289(protein homotetramerization);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0016032(viral process);GO:0032793(positive regulation of CREB transcription factor activity);GO:0008140(cAMP response element binding protein binding);GO:0042116(macrophage activation);GO:0043951(negative regulation of cAMP-mediated signaling);GO:0050995(negative regulation of lipid catabolic process);GO:0097009(energy homeostasis)","05166(HTLV-I infection)","K16334","NA","CREB regulated transcription coactivator 3 [Source:HGNC Symbol;Acc:HGNC:26148]",{"v":9.655149,"d":"9.66"},{"v":1.305678,"d":"1.31"},{"v":7.39473974440865,"d":"7.39"},{"v":2.88649937300951,"d":"2.89"},{"v":2.99324249333587E-5,"d":"0.00"},{"v":9.56292107915897E-4,"d":"0.00"},"up","yes"]
[190921,0,"chr9","+",69174165,69255204,"ENST00000377245",23,4611,"ENSG00000119139","TJP2","GO:0005923(bicellular tight junction);GO:0005634(nucleus);GO:0016020(membrane);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0030054(cell junction);GO:0005515(protein binding);GO:0005654(nucleoplasm);GO:0045296(cadherin binding);GO:0005912(adherens junction);GO:0046037(GMP metabolic process);GO:0046710(GDP metabolic process);GO:0019904(protein domain specific binding);GO:0030674(protein binding, bridging);GO:0035329(hippo signaling);GO:0004385(guanylate kinase activity);GO:0050892(intestinal absorption);GO:0090557(establishment of endothelial intestinal barrier);GO:0090559(regulation of membrane permeability);GO:0008022(protein C-terminus binding);GO:0010033(response to organic substance);GO:0071847(TNFSF11-mediated signaling pathway);GO:2001205(negative regulation of osteoclast development);GO:0005911(cell-cell junction);GO:0070160(occluding junction)","04530(Tight junction);05110(Vibrio cholerae infection)","K06098","NA","tight junction protein 2 [Source:HGNC Symbol;Acc:HGNC:11828]",{"v":0.395206,"d":"0.40"},{"v":3.24055,"d":"3.24"},{"v":0.121956458008671,"d":"0.12"},{"v":-3.03556193912802,"d":"-3.04"},{"v":2.99799108351038e-05,"d":"0.00"},{"v":9.56292107915897E-4,"d":"0.00"},"down","yes"]
[164407,0,"chr6","-",31530219,31542448,"ENST00000458640",11,2003,"MSTRG.12858","DDX39B","GO:0003676(nucleic acid binding);GO:0016607(nuclear speck);GO:0005524(ATP binding);GO:0003723(RNA binding);GO:0006397(mRNA processing);GO:0006810(transport);GO:0008380(RNA splicing);GO:0051028(mRNA transport);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0000166(nucleotide binding);GO:0016787(hydrolase activity);GO:0004386(helicase activity);GO:0005515(protein binding);GO:0005681(spliceosomal complex);GO:0006406(mRNA export from nucleus);GO:0042802(identical protein binding);GO:0005730(nucleolus);GO:0005654(nucleoplasm);GO:0016887(ATPase activity);GO:0000398(mRNA splicing, via spliceosome);GO:0006369(termination of RNA polymerase II transcription);GO:0006405(RNA export from nucleus);GO:0031124(mRNA 3'-end processing);GO:0032786(positive regulation of DNA-templated transcription, elongation);GO:0004004(ATP-dependent RNA helicase activity);GO:0000346(transcription export complex);GO:0008186(RNA-dependent ATPase activity);GO:0046784(viral mRNA export from host cell nucleus);GO:2000002(negative regulation of DNA damage checkpoint);GO:0005687(U4 snRNP);GO:0005688(U6 snRNP);GO:0017070(U6 snRNA binding);GO:0030621(U4 snRNA binding);GO:0043008(ATP-dependent protein binding);GO:0000245(spliceosomal complex assembly);GO:0010501(RNA secondary structure unwinding);GO:0032403(protein complex binding);GO:0001889(liver development);GO:0045727(positive regulation of translation);GO:0061051(positive regulation of cell growth involved in cardiac muscle cell development);GO:1904707(positive regulation of vascular smooth muscle cell proliferation);GO:2000573(positive regulation of DNA biosynthetic process);GO:0016363(nuclear matrix);GO:0043234(protein complex)","03040(Spliceosome);03013(RNA transport);03015(mRNA surveillance pathway);05164(Influenza A)","K12812","EC:3.6.4.13","DExD-box helicase 39B [Source:HGNC Symbol;Acc:HGNC:13917]",{"v":1.059938,"d":"1.06"},{"v":8.668615,"d":"8.67"},{"v":0.122273050539215,"d":"0.12"},{"v":-3.03182163164144,"d":"-3.03"},{"v":3.0352801523231e-05,"d":"0.00"},{"v":0.000966642329849882,"d":"0.00"},"down","yes"]
[184089,"j","chr8","+",58559892,58582889,"MSTRG.14373.11",9,3965,"MSTRG.14373","SDCBP","NA","NA","NA","NA","NA",{"v":2.669141,"d":"2.67"},{"v":21.214104,"d":"21.21"},{"v":0.125819171999911,"d":"0.13"},{"v":-2.99057632178178,"d":"-2.99"},{"v":3.08721012038051E-5,"d":"0.00"},{"v":0.00098161483572863,"d":"0.00"},"down","yes"]
[23065,0,"chr10","+",102133030,102150325,"ENST00000278070",14,5330,"ENSG00000148840","PPRC1","GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0008134(transcription factor binding);GO:0003712(transcription cofactor activity);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0007005(mitochondrion organization);GO:0030374(ligand-dependent nuclear receptor transcription coactivator activity);GO:0001104(RNA polymerase II transcription cofactor activity);GO:0051091(positive regulation of sequence-specific DNA binding transcription factor activity);GO:1903506(regulation of nucleic acid-templated transcription)","NA","NA","NA","peroxisome proliferator-activated receptor gamma, coactivator-related 1 [Source:HGNC Symbol;Acc:HGNC:30025]",{"v":5.184372,"d":"5.18"},{"v":0.699706,"d":"0.70"},{"v":7.4093576444964,"d":"7.41"},{"v":2.88934847326396,"d":"2.89"},{"v":3.10304252971913e-05,"d":"0.00"},{"v":0.000985080337574428,"d":"0.00"},"up","yes"]
[193869,0,"chr9","+",128552590,128633658,"ENST00000372739",57,7868,"MSTRG.15015","SPTAN1","GO:0005737(cytoplasm);GO:0043231(intracellular membrane-bounded organelle);GO:0046872(metal ion binding);GO:0005509(calcium ion binding);GO:0003779(actin binding);GO:0051693(actin filament capping);GO:0043547(positive regulation of GTPase activity);GO:0015630(microtubule cytoskeleton);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0007010(cytoskeleton organization);GO:0005576(extracellular region);GO:0005516(calmodulin binding);GO:0005829(cytosol);GO:0045296(cadherin binding);GO:0070062(extracellular exosome);GO:0005938(cell cortex);GO:0000165(MAPK cascade);GO:0043312(neutrophil degranulation);GO:0005200(structural constituent of cytoskeleton);GO:0016020(membrane);GO:0007411(axon guidance);GO:0035580(specific granule lumen);GO:1904724(tertiary granule lumen);GO:0006888(ER to Golgi vesicle-mediated transport);GO:0005088(Ras guanyl-nucleotide exchange factor activity);GO:1903561(extracellular vesicle);GO:0008091(spectrin)","04210(Apoptosis)","K06114","NA","spectrin alpha, non-erythrocytic 1 [Source:HGNC Symbol;Acc:HGNC:11273]",{"v":7.175931,"d":"7.18"},{"v":0.978493,"d":"0.98"},{"v":7.33365593826425,"d":"7.33"},{"v":2.87453258295664,"d":"2.87"},{"v":3.13994645165388e-05,"d":"0.00"},{"v":0.000995213503914676,"d":"0.00"},"up","yes"]
[45022,0,"chr12","-",89347232,89353271,"ENST00000279488",3,4400,"MSTRG.3580","DUSP6","GO:0005737(cytoplasm);GO:0016787(hydrolase activity);GO:0008138(protein tyrosine/serine/threonine phosphatase activity);GO:0016791(phosphatase activity);GO:0006470(protein dephosphorylation);GO:0016311(dephosphorylation);GO:0035335(peptidyl-tyrosine dephosphorylation);GO:0004721(phosphoprotein phosphatase activity);GO:0017017(MAP kinase tyrosine/serine/threonine phosphatase activity);GO:0000188(inactivation of MAPK activity);GO:0004725(protein tyrosine phosphatase activity);GO:0001933(negative regulation of protein phosphorylation);GO:0010033(response to organic substance);GO:0010942(positive regulation of cell death);GO:0014070(response to organic cyclic compound);GO:0030154(cell differentiation);GO:0042493(response to drug);GO:0060420(regulation of heart growth);GO:0070373(negative regulation of ERK1 and ERK2 cascade);GO:0070848(response to growth factor);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0000165(MAPK cascade);GO:0043065(positive regulation of apoptotic process);GO:0000187(activation of MAPK activity);GO:0009953(dorsal/ventral pattern formation);GO:0040036(regulation of fibroblast growth factor receptor signaling pathway);GO:0042663(regulation of endodermal cell fate specification);GO:0051409(response to nitrosative stress)","04010(MAPK signaling pathway);05202(Transcriptional misregulation in cancers);05221(Acute myeloid leukemia)","K21946","EC:3.1.3.16;EC:3.1.3.48","dual specificity phosphatase 6 [Source:HGNC Symbol;Acc:HGNC:3072]",{"v":5.465777,"d":"5.47"},{"v":43.119106,"d":"43.12"},{"v":0.126759979671193,"d":"0.13"},{"v":-2.97982876142308,"d":"-2.98"},{"v":3.18074611385567e-05,"d":"0.00"},{"v":0.00100654735976973,"d":"0.00"},"down","yes"]
[553,0,"chr1","-",1702736,1737688,"ENST00000598846",20,5079,"MSTRG.77","AL031282.2","NA","NA","NA","NA","NA",{"v":3.848878,"d":"3.85"},{"v":0.520704,"d":"0.52"},{"v":7.39168126229105,"d":"7.39"},{"v":2.88590254744305,"d":"2.89"},{"v":3.30297896181261e-05,"d":"0.00"},{"v":0.00104357411249168,"d":"0.00"},"up","yes"]
[137505,0,"chr3","+",58008400,58170774,"ENST00000490882",47,8079,"ENSG00000136068","FLNB","GO:0003723(RNA binding);GO:0005737(cytoplasm);GO:0016021(integral component of membrane);GO:0005829(cytosol);GO:0003779(actin binding);GO:0005886(plasma membrane);GO:0030036(actin cytoskeleton organization);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0030154(cell differentiation);GO:0007275(multicellular organism development);GO:0005925(focal adhesion);GO:0042802(identical protein binding);GO:0045296(cadherin binding);GO:0070062(extracellular exosome);GO:0005938(cell cortex);GO:0007517(muscle organ development);GO:0031012(extracellular matrix);GO:0007165(signal transduction);GO:0015629(actin cytoskeleton);GO:0030018(Z disc);GO:0003334(keratinocyte development);GO:0003382(epithelial cell morphogenesis);GO:0007016(cytoskeletal anchoring at plasma membrane);GO:0007519(skeletal muscle tissue development);GO:0001725(stress fiber);GO:0005634(nucleus);GO:0005903(brush border);GO:0043005(neuron projection);GO:0043025(neuronal cell body)","04010(MAPK signaling pathway);04510(Focal adhesion);05205(Proteoglycans in cancer);05132(Salmonella infection)","K04437","NA","filamin B [Source:HGNC Symbol;Acc:HGNC:3755]",{"v":0.13502,"d":"0.14"},{"v":1.113063,"d":"1.11"},{"v":0.121304903675713,"d":"0.12"},{"v":-3.04329022319531,"d":"-3.04"},{"v":3.31106999694911e-05,"d":"0.00"},{"v":0.00104447781515134,"d":"0.00"},"down","yes"]
[199280,0,"chrX","+",108091668,108154671,"ENST00000372232",13,2315,"MSTRG.15399","ATG4A","GO:0006810(transport);GO:0005737(cytoplasm);GO:0015031(protein transport);GO:0006914(autophagy);GO:0016787(hydrolase activity);GO:0005515(protein binding);GO:0008233(peptidase activity);GO:0008234(cysteine-type peptidase activity);GO:0006508(proteolysis);GO:0004197(cysteine-type endopeptidase activity);GO:0000045(autophagosome assembly);GO:0000422(mitophagy);GO:0005829(cytosol);GO:0044804(nucleophagy);GO:0006501(C-terminal protein lipidation);GO:0006612(protein targeting to membrane);GO:0051697(protein delipidation)","04140(Autophagy - animal);04136(Autophagy - other eukaryotes)","K08342","EC:3.4.22.-","autophagy related 4A cysteine peptidase [Source:HGNC Symbol;Acc:HGNC:16489]",{"v":0.336551,"d":"0.34"},{"v":2.838738,"d":"2.84"},{"v":0.118556555765273,"d":"0.12"},{"v":-3.07635265384266,"d":"-3.08"},{"v":3.31911145129272e-05,"d":"0.00"},{"v":1.0453630514103E-3,"d":"0.00"},"down","yes"]
[181922,"j","chr8","+",22056878,22082525,"MSTRG.14210.17",15,2511,"MSTRG.14210","DMTN","NA","NA","NA","NA","NA",{"v":26.814215,"d":"26.81"},{"v":3.701377,"d":"3.70"},{"v":7.24438904764362,"d":"7.24"},{"v":2.85686402586216,"d":"2.86"},{"v":3.41863563315143e-05,"d":"0.00"},{"v":0.00107427057202721,"d":"0.00"},"up","yes"]
[11318,0,"chr1","-",154156359,154183147,"ENST00000469717",5,4041,"MSTRG.1004","TPM3","GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0003779(actin binding);GO:0015629(actin cytoskeleton);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0003674(molecular_function);GO:0070062(extracellular exosome);GO:0008307(structural constituent of muscle);GO:0051015(actin filament binding);GO:0007015(actin filament organization);GO:0001725(stress fiber);GO:0006936(muscle contraction);GO:0006928(movement of cell or subcellular component);GO:0030049(muscle filament sliding);GO:0005862(muscle thin filament tropomyosin);GO:0005884(actin filament)","04260(Cardiac muscle contraction);04261(Adrenergic signaling in cardiomyocytes);05200(Pathways in cancer);05216(Thyroid cancer);05410(Hypertrophic cardiomyopathy (HCM));05414(Dilated cardiomyopathy (DCM))","NA","NA","tropomyosin 3 [Source:HGNC Symbol;Acc:HGNC:12012]",{"v":13.070652,"d":"13.07"},{"v":1.800067,"d":"1.80"},{"v":7.26120305521961,"d":"7.26"},{"v":2.86020859753349,"d":"2.86"},{"v":3.4251011739188e-05,"d":"0.00"},{"v":0.00107427057202721,"d":"0.00"},"up","yes"]
[170567,0,"chr6","-",159682165,159693278,"ENST00000337404",4,991,"MSTRG.13403","SOD2","GO:0046872(metal ion binding);GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0004784(superoxide dismutase activity);GO:0006801(superoxide metabolic process);GO:0003677(DNA binding);GO:0019825(oxygen binding);GO:0019899(enzyme binding);GO:0030145(manganese ion binding);GO:0042802(identical protein binding);GO:0000302(response to reactive oxygen species);GO:0000303(response to superoxide);GO:0001306(age-dependent response to oxidative stress);GO:0001666(response to hypoxia);GO:0001836(release of cytochrome c from mitochondria);GO:0001889(liver development);GO:0003032(detection of oxygen);GO:0003069(acetylcholine-mediated vasodilation involved in regulation of systemic arterial blood pressure);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0006749(glutathione metabolic process);GO:0006979(response to oxidative stress);GO:0007005(mitochondrion organization);GO:0007507(heart development);GO:0007568(aging);GO:0007626(locomotory behavior);GO:0008217(regulation of blood pressure);GO:0008630(intrinsic apoptotic signaling pathway in response to DNA damage);GO:0008631(intrinsic apoptotic signaling pathway in response to oxidative stress);GO:0008637(apoptotic mitochondrial changes);GO:0009314(response to radiation);GO:0009409(response to cold);GO:0009791(post-embryonic development);GO:0010042(response to manganese ion);GO:0010043(response to zinc ion);GO:0010269(response to selenium ion);GO:0010332(response to gamma radiation);GO:0014823(response to activity);GO:0019430(removal of superoxide radicals);GO:0022904(respiratory electron transport chain);GO:0030097(hemopoiesis);GO:0031667(response to nutrient levels);GO:0032496(response to lipopolysaccharide);GO:0033591(response to L-ascorbic acid);GO:0034021(response to silicon dioxide);GO:0035900(response to isolation stress);GO:0035902(response to immobilization stress);GO:0042311(vasodilation);GO:0042493(response to drug);GO:0042542(response to hydrogen peroxide);GO:0042554(superoxide anion generation);GO:0042743(hydrogen peroxide metabolic process);GO:0043066(negative regulation of apoptotic process);GO:0045429(positive regulation of nitric oxide biosynthetic process);GO:0045599(negative regulation of fat cell differentiation);GO:0046686(response to cadmium ion);GO:0048147(negative regulation of fibroblast proliferation);GO:0048666(neuron development);GO:0048678(response to axon injury);GO:0048773(erythrophore differentiation);GO:0050665(hydrogen peroxide biosynthetic process);GO:0050790(regulation of catalytic activity);GO:0051260(protein homooligomerization);GO:0051602(response to electrical stimulus);GO:0051881(regulation of mitochondrial membrane potential);GO:0055072(iron ion homeostasis);GO:0055093(response to hyperoxia);GO:0071000(response to magnetism);GO:0071361(cellular response to ethanol);GO:0005737(cytoplasm);GO:0005739(mitochondrion);GO:0005743(mitochondrial inner membrane);GO:0042645(mitochondrial nucleoid);GO:0043209(myelin sheath);GO:0008285(negative regulation of cell proliferation);GO:0030335(positive regulation of cell migration);GO:0005759(mitochondrial matrix);GO:0070062(extracellular exosome);GO:0035722(interleukin-12-mediated signaling pathway);GO:0051289(protein homotetramerization);GO:0034599(cellular response to oxidative stress);GO:0043524(negative regulation of neuron apoptotic process);GO:1902176(negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway);GO:0001315(age-dependent response to reactive oxygen species);GO:0032364(oxygen homeostasis)","04068(FoxO signaling pathway);04146(Peroxisome);04211(Longevity regulating pathway - mammal);04213(Longevity regulating pathway - multiple species);05016(Huntington's disease)","K04564","EC:1.15.1.1","superoxide dismutase 2 [Source:HGNC Symbol;Acc:HGNC:11180]",{"v":14.387585,"d":"14.39"},{"v":112.575981,"d":"112.58"},{"v":0.127803327780906,"d":"0.13"},{"v":-2.96800269279256,"d":"-2.97"},{"v":3.4270350279514e-05,"d":"0.00"},{"v":0.00107427057202721,"d":"0.00"},"down","yes"]
[112194,0,"chr2","+",89862482,89862981,"ENST00000448155",2,376,"MSTRG.8918","IGKV1D-39","GO:0016020(membrane);GO:0005886(plasma membrane);GO:0005576(extracellular region);GO:0006508(proteolysis);GO:0006955(immune response);GO:0002376(immune system process);GO:0003823(antigen binding);GO:0002250(adaptive immune response);GO:0004252(serine-type endopeptidase activity);GO:0006898(receptor-mediated endocytosis);GO:0006956(complement activation);GO:0006958(complement activation, classical pathway);GO:0030449(regulation of complement activation);GO:0038095(Fc-epsilon receptor signaling pathway);GO:0038096(Fc-gamma receptor signaling pathway involved in phagocytosis);GO:0050776(regulation of immune response);GO:0050900(leukocyte migration)","NA","NA","NA","immunoglobulin kappa variable 1D-39 [Source:HGNC Symbol;Acc:HGNC:5756]",{"v":20.265753,"d":"20.27"},{"v":2.668268,"d":"2.67"},{"v":7.59509651954002,"d":"7.60"},{"v":2.92506829881254,"d":"2.93"},{"v":3.48262681845736e-05,"d":"0.00"},{"v":0.00108998577289901,"d":"0.00"},"up","yes"]
[161893,0,"chr5","-",179614179,179618899,"ENST00000502904",7,2913,"MSTRG.12597","HNRNPH1","GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0006397(mRNA processing);GO:0008380(RNA splicing);GO:0005634(nucleus);GO:0016020(membrane);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0030529(intracellular ribonucleoprotein complex);GO:0005681(spliceosomal complex);GO:0005515(protein binding);GO:0043484(regulation of RNA splicing);GO:0000398(mRNA splicing, via spliceosome);GO:0008543(fibroblast growth factor receptor signaling pathway);GO:0016070(RNA metabolic process);GO:0006396(RNA processing);GO:0071013(catalytic step 2 spliceosome);GO:0008266(poly(U) RNA binding)","NA","NA","NA","heterogeneous nuclear ribonucleoprotein H1 [Source:HGNC Symbol;Acc:HGNC:5041]",{"v":3.093832,"d":"3.09"},{"v":0.411015,"d":"0.41"},{"v":7.52729705728501,"d":"7.53"},{"v":2.9121319071153,"d":"2.91"},{"v":3.5450208554341E-5,"d":"0.00"},{"v":0.00110777740909715,"d":"0.00"},"up","yes"]
[76667,0,"chr16","+",87959871,88077315,"ENST00000538234",13,2372,"MSTRG.6224","BANP","GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0016569(covalent chromatin modification);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0007049(cell cycle);GO:0016604(nuclear body);GO:0007275(multicellular organism development);GO:1901796(regulation of signal transduction by p53 class mediator);GO:0002039(p53 binding);GO:0034504(protein localization to nucleus);GO:0042177(negative regulation of protein catabolic process);GO:0045893(positive regulation of transcription, DNA-templated)","NA","NA","NA","BTG3 associated nuclear protein [Source:HGNC Symbol;Acc:HGNC:13450]",{"v":3.504512,"d":"3.50"},{"v":0.465101,"d":"0.47"},{"v":7.53494832305241,"d":"7.53"},{"v":2.91359761741943,"d":"2.91"},{"v":3.55591070028483e-05,"d":"0.00"},{"v":0.00110944413848887,"d":"0.00"},"up","yes"]
[74756,0,"chr16","+",68084751,68226471,"ENST00000569766",10,3555,"MSTRG.6049","NFATC3","GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0006351(transcription, DNA-templated);GO:0005515(protein binding);GO:0038095(Fc-epsilon receptor signaling pathway);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0006954(inflammatory response);GO:0006366(transcription from RNA polymerase II promoter);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0001077(transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:1902894(negative regulation of pri-miRNA transcription from RNA polymerase II promoter);GO:0001227(transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding);GO:0045893(positive regulation of transcription, DNA-templated)","04010(MAPK signaling pathway);04310(Wnt signaling pathway);04022(cGMP - PKG signaling pathway);04218(Cellular senescence);04660(T cell receptor signaling pathway);04658(Th1 and Th2 cell differentiation);04659(Th17 cell differentiation);04662(B cell receptor signaling pathway);04921(Oxytocin signaling pathway);04360(Axon guidance);05166(HTLV-I infection);05161(Hepatitis B);05167(Kaposi's sarcoma-associated herpesvirus infection)","NA","NA","nuclear factor of activated T-cells 3 [Source:HGNC Symbol;Acc:HGNC:7777]",{"v":20.4006,"d":"20.40"},{"v":2.831228,"d":"2.83"},{"v":7.20556592404427,"d":"7.21"},{"v":2.84911174389748,"d":"2.85"},{"v":3.57706160350699e-05,"d":"0.00"},{"v":1.11430212322664E-3,"d":"0.00"},"up","yes"]
[43396,0,"chr12","-",57472255,57479850,"ENST00000393791",18,2597,"MSTRG.3490","ARHGAP9","GO:0007165(signal transduction);GO:0043547(positive regulation of GTPase activity);GO:0005515(protein binding);GO:0005096(GTPase activator activity);GO:0005576(extracellular region);GO:0008289(lipid binding);GO:0005829(cytosol);GO:0051056(regulation of small GTPase mediated signal transduction);GO:0005547(phosphatidylinositol-3,4,5-trisphosphate binding);GO:0043312(neutrophil degranulation);GO:0034774(secretory granule lumen)","NA","NA","NA","Rho GTPase activating protein 9 [Source:HGNC Symbol;Acc:HGNC:14130]",{"v":3.225331,"d":"3.23"},{"v":0.429234,"d":"0.43"},{"v":7.51415544900917,"d":"7.51"},{"v":2.90961096202638,"d":"2.91"},{"v":3.61393922161349e-05,"d":"0.00"},{"v":1.12403642332053E-3,"d":"0.00"},"up","yes"]
[61396,0,"chr15","-",41517179,41544245,"ENST00000562303",24,5897,"ENSG00000103932","RPAP1","GO:0005634(nucleus);GO:0016740(transferase activity);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0016779(nucleotidyltransferase activity);GO:0003899(DNA-directed 5'-3' RNA polymerase activity);GO:0006366(transcription from RNA polymerase II promoter)","NA","NA","NA","RNA polymerase II associated protein 1 [Source:HGNC Symbol;Acc:HGNC:24567]",{"v":1.026852,"d":"1.03"},{"v":0.134489,"d":"0.13"},{"v":7.63521180170869,"d":"7.64"},{"v":2.93266817811401,"d":"2.93"},{"v":3.68748446388311e-05,"d":"0.00"},{"v":1.14512736819313E-3,"d":"0.00"},"up","yes"]
[105411,0,"chr19","+",54191253,54193666,"ENST00000396388",4,1349,"MSTRG.8408","TSEN34","GO:0005634(nucleus);GO:0000213(tRNA-intron endonuclease activity);GO:0090501(RNA phosphodiester bond hydrolysis);GO:0090502(RNA phosphodiester bond hydrolysis, endonucleolytic);GO:0000214(tRNA-intron endonuclease complex);GO:0000379(tRNA-type intron splice site recognition and cleavage);GO:0006388(tRNA splicing, via endonucleolytic cleavage and ligation);GO:0006397(mRNA processing);GO:0008033(tRNA processing);GO:0016829(lyase activity);GO:0090305(nucleic acid phosphodiester bond hydrolysis);GO:0004519(endonuclease activity);GO:0005730(nucleolus);GO:0005654(nucleoplasm)","NA","NA","NA","tRNA splicing endonuclease subunit 34 [Source:HGNC Symbol;Acc:HGNC:15506]",{"v":3.317004,"d":"3.32"},{"v":25.971012,"d":"25.97"},{"v":0.12771947431236,"d":"0.13"},{"v":-2.96894957492271,"d":"-2.97"},{"v":3.7467886512179e-05,"d":"0.00"},{"v":0.00116173720166955,"d":"0.00"},"down","yes"]
[85903,0,"chr17","-",56887909,56914038,"ENST00000316881",9,5734,"MSTRG.7040","TRIM25","GO:0003723(RNA binding);GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0016740(transferase activity);GO:0016567(protein ubiquitination);GO:0016874(ligase activity);GO:0005515(protein binding);GO:0016604(nuclear body);GO:0002376(immune system process);GO:0045087(innate immune response);GO:0051607(defense response to virus);GO:1904264(ubiquitin protein ligase activity involved in ERAD pathway);GO:0045296(cadherin binding);GO:0016579(protein deubiquitination);GO:0016032(viral process);GO:0042787(protein ubiquitination involved in ubiquitin-dependent protein catabolic process);GO:0043123(positive regulation of I-kappaB kinase/NF-kappaB signaling);GO:0051092(positive regulation of NF-kappaB transcription factor activity);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0051091(positive regulation of sequence-specific DNA binding transcription factor activity);GO:0060333(interferon-gamma-mediated signaling pathway);GO:0043627(response to estrogen);GO:0019985(translesion synthesis);GO:0032480(negative regulation of type I interferon production);GO:0004842(ubiquitin-protein transferase activity);GO:0006513(protein monoubiquitination);GO:0030433(ubiquitin-dependent ERAD pathway);GO:0036503(ERAD pathway);GO:0033280(response to vitamin D);GO:0046596(regulation of viral entry into host cell);GO:0046597(negative regulation of viral entry into host cell);GO:1902186(regulation of viral release from host cell);GO:1902187(negative regulation of viral release from host cell);GO:1990830(cellular response to leukemia inhibitory factor)","04064(NF-kappa B signaling pathway);04622(RIG-I-like receptor signaling pathway);05164(Influenza A)","K10652","EC:2.3.2.27","tripartite motif containing 25 [Source:HGNC Symbol;Acc:HGNC:12932]",{"v":0.945768,"d":"0.95"},{"v":7.384883,"d":"7.38"},{"v":0.128068108865096,"d":"0.13"},{"v":-2.96501683006051,"d":"-2.97"},{"v":3.75353876278959e-05,"d":"0.00"},{"v":1.16202576768035E-3,"d":"0.00"},"down","yes"]
[201174,"j","chrX","+",154379242,154381523,"MSTRG.15499.2",5,1548,"MSTRG.15499","EMD","NA","NA","NA","NA","NA",{"v":4.809931,"d":"4.81"},{"v":0.637562,"d":"0.64"},{"v":7.54425608803536,"d":"7.54"},{"v":2.91537864879509,"d":"2.92"},{"v":3.77505341578999e-05,"d":"0.00"},{"v":0.001166877192051,"d":"0.00"},"up","yes"]
[142257,0,"chr3","+",160399668,160433990,"ENST00000462787",22,5033,"ENSG00000113810","SMC4","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016607(nuclear speck);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0005829(cytosol);GO:0051301(cell division);GO:0005694(chromosome);GO:0005515(protein binding);GO:0051276(chromosome organization);GO:0007049(cell cycle);GO:0005654(nucleoplasm);GO:0030261(chromosome condensation);GO:0046982(protein heterodimerization activity);GO:0000070(mitotic sister chromatid segregation);GO:0007076(mitotic chromosome condensation);GO:0000796(condensin complex);GO:0010032(meiotic chromosome condensation);GO:0045132(meiotic chromosome segregation);GO:0051383(kinetochore organization)","NA","NA","NA","structural maintenance of chromosomes 4 [Source:HGNC Symbol;Acc:HGNC:14013]",{"v":1.597815,"d":"1.60"},{"v":0.211553,"d":"0.21"},{"v":7.55278819019347,"d":"7.55"},{"v":2.91700932862294,"d":"2.92"},{"v":3.85615233319903e-05,"d":"0.00"},{"v":0.00119010277881481,"d":"0.00"},"up","yes"]
[70714,0,"chr16","+",22297455,22329091,"ENST00000564061",18,4800,"ENSG00000058600","POLR3E","GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0006351(transcription, DNA-templated);GO:0003899(DNA-directed 5'-3' RNA polymerase activity);GO:0002376(immune system process);GO:0045087(innate immune response);GO:0051607(defense response to virus);GO:0005829(cytosol);GO:0001056(RNA polymerase III activity);GO:0006383(transcription from RNA polymerase III promoter);GO:0032481(positive regulation of type I interferon production);GO:0005666(DNA-directed RNA polymerase III complex)","00230(Purine metabolism);00240(Pyrimidine metabolism);03020(RNA polymerase);04623(Cytosolic DNA-sensing pathway);05169(Epstein-Barr virus infection)","NA","NA","RNA polymerase III subunit E [Source:HGNC Symbol;Acc:HGNC:30347]",{"v":1.78531,"d":"1.79"},{"v":0.238098,"d":"0.24"},{"v":7.49821502070576,"d":"7.50"},{"v":2.90654719730619,"d":"2.91"},{"v":3.86945559415724e-05,"d":"0.00"},{"v":0.00119236557568105,"d":"0.00"},"up","yes"]
[15548,0,"chr1","+",207496228,207640208,"ENST00000400960",39,6959,"MSTRG.1357","CR1","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0002376(immune system process);GO:0045087(innate immune response);GO:0030449(regulation of complement activation);GO:0005886(plasma membrane);GO:0005887(integral component of plasma membrane);GO:0046718(viral entry into host cell);GO:0070062(extracellular exosome);GO:0016032(viral process);GO:0002430(complement receptor mediated signaling pathway);GO:0043312(neutrophil degranulation);GO:0006958(complement activation, classical pathway);GO:0009986(cell surface);GO:0030667(secretory granule membrane);GO:0001618(virus receptor activity);GO:0101003(ficolin-1-rich granule membrane);GO:0045589(regulation of regulatory T cell differentiation);GO:1900005(positive regulation of serine-type endopeptidase activity);GO:1900004(negative regulation of serine-type endopeptidase activity);GO:0001851(complement component C3b binding);GO:0001855(complement component C4b binding);GO:0001861(complement component C4b receptor activity);GO:0004877(complement component C3b receptor activity);GO:0045957(negative regulation of complement activation, alternative pathway);GO:0045959(negative regulation of complement activation, classical pathway)","04640(Hematopoietic cell lineage);04610(Complement and coagulation cascades);05134(Legionellosis);05152(Tuberculosis);05144(Malaria);05140(Leishmaniasis)","K04011","NA","complement C3b/C4b receptor 1 (Knops blood group) [Source:HGNC Symbol;Acc:HGNC:2334]",{"v":0.363421,"d":"0.36"},{"v":2.863289,"d":"2.86"},{"v":0.12692431675601,"d":"0.13"},{"v":-2.97795960094446,"d":"-2.98"},{"v":3.89006002891005e-05,"d":"0.00"},{"v":1.19686777592105E-3,"d":"0.00"},"down","yes"]
[200103,0,"chrX","-",134769566,134797134,"ENST00000370790",9,4246,"ENSG00000156504","FAM122B","GO:0005581(collagen trimer)","NA","NA","NA","family with sequence similarity 122B [Source:HGNC Symbol;Acc:HGNC:30490]",{"v":1.764666,"d":"1.76"},{"v":0.235963,"d":"0.24"},{"v":7.47857079287854,"d":"7.48"},{"v":2.902762587354,"d":"2.90"},{"v":3.93667129070963e-05,"d":"0.00"},{"v":0.001209345420506,"d":"0.00"},"up","yes"]
[65068,0,"chr15","-",76216250,76311448,"ENST00000267950",11,1289,"MSTRG.5304","ETFA","GO:0016491(oxidoreductase activity);GO:0050660(flavin adenine dinucleotide binding);GO:0055114(oxidation-reduction process);GO:0005739(mitochondrion);GO:0005759(mitochondrial matrix);GO:0009055(electron carrier activity);GO:0005515(protein binding);GO:0070062(extracellular exosome);GO:0033539(fatty acid beta-oxidation using acyl-CoA dehydrogenase);GO:0022904(respiratory electron transport chain)","NA","NA","NA","electron transfer flavoprotein alpha subunit [Source:HGNC Symbol;Acc:HGNC:3481]",{"v":0.52414,"d":"0.52"},{"v":4.422067,"d":"4.42"},{"v":0.11852828100524,"d":"0.12"},{"v":-3.07669676573806,"d":"-3.08"},{"v":3.9698144844426e-05,"d":"0.00"},{"v":1.21765369624193E-3,"d":"0.00"},"down","yes"]
[85278,0,"chr17","-",49598884,49678110,"ENST00000393328",11,2985,"MSTRG.7004","SPOP","GO:0005634(nucleus);GO:0016607(nuclear speck);GO:0016567(protein ubiquitination);GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0005654(nucleoplasm);GO:0030162(regulation of proteolysis);GO:0042787(protein ubiquitination involved in ubiquitin-dependent protein catabolic process);GO:0019005(SCF ubiquitin ligase complex);GO:0031625(ubiquitin protein ligase binding);GO:0043161(proteasome-mediated ubiquitin-dependent protein catabolic process);GO:0031463(Cul3-RING ubiquitin ligase complex);GO:0001085(RNA polymerase II transcription factor binding);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0042593(glucose homeostasis);GO:0043433(negative regulation of sequence-specific DNA binding transcription factor activity);GO:1902237(positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway);GO:2000676(positive regulation of type B pancreatic cell apoptotic process)","04340(Hedgehog signaling pathway)","K10523","NA","speckle type BTB/POZ protein [Source:HGNC Symbol;Acc:HGNC:11254]",{"v":0.250613,"d":"0.25"},{"v":2.091968,"d":"2.09"},{"v":0.119797721571267,"d":"0.12"},{"v":-3.06132762506695,"d":"-3.06"},{"v":3.98080951575723e-05,"d":"0.00"},{"v":0.00121915344188099,"d":"0.00"},"down","yes"]
[10649,0,"chr1","-",150810859,150876579,"ENST00000354396",22,3538,"MSTRG.930","ARNT","GO:0045648(positive regulation of erythrocyte differentiation);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0046983(protein dimerization activity);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0005515(protein binding);GO:0030522(intracellular receptor signaling pathway);GO:0016604(nuclear body);GO:0005667(transcription factor complex);GO:0005654(nucleoplasm);GO:0061418(regulation of transcription from RNA polymerase II promoter in response to hypoxia);GO:0006805(xenobiotic metabolic process);GO:0046982(protein heterodimerization activity);GO:0003713(transcription coactivator activity);GO:0001938(positive regulation of endothelial cell proliferation);GO:0045893(positive regulation of transcription, DNA-templated);GO:0017162(aryl hydrocarbon receptor binding);GO:0090575(RNA polymerase II transcription factor complex);GO:0003705(transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding);GO:0043565(sequence-specific DNA binding);GO:0008134(transcription factor binding);GO:0010575(positive regulation of vascular endothelial growth factor production);GO:0045821(positive regulation of glycolytic process);GO:0030949(positive regulation of vascular endothelial growth factor receptor signaling pathway);GO:0001666(response to hypoxia);GO:0043619(regulation of transcription from RNA polymerase II promoter in response to oxidative stress);GO:0042789(mRNA transcription from RNA polymerase II promoter);GO:0000989(transcription factor activity, transcription factor binding);GO:0004874(aryl hydrocarbon receptor activity);GO:0035326(enhancer binding);GO:0001892(embryonic placenta development);GO:0030154(cell differentiation);GO:0033235(positive regulation of protein sumoylation);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0046886(positive regulation of hormone biosynthetic process)","04066(HIF-1 signaling pathway);05200(Pathways in cancer);05204(Chemical carcinogenesis);05211(Renal cell carcinoma)","K09097","NA","aryl hydrocarbon receptor nuclear translocator [Source:HGNC Symbol;Acc:HGNC:700]",{"v":1.447021,"d":"1.45"},{"v":0.18951,"d":"0.19"},{"v":7.63559178935148,"d":"7.64"},{"v":2.93273997607601,"d":"2.93"},{"v":4.00858268914126e-05,"d":"0.00"},{"v":0.00122539561008543,"d":"0.00"},"up","yes"]
[35523,0,"chr11","-",117205074,117226876,"ENST00000534529",11,5393,"MSTRG.2885","PCSK7","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016787(hydrolase activity);GO:0005794(Golgi apparatus);GO:0008233(peptidase activity);GO:0006508(proteolysis);GO:0004252(serine-type endopeptidase activity);GO:0008236(serine-type peptidase activity);GO:0030173(integral component of Golgi membrane);GO:0016486(peptide hormone processing);GO:0016485(protein processing)","NA","NA","NA","proprotein convertase subtilisin/kexin type 7 [Source:HGNC Symbol;Acc:HGNC:8748]",{"v":3.231066,"d":"3.23"},{"v":0.445993,"d":"0.45"},{"v":7.2446563062649,"d":"7.24"},{"v":2.85691724851116,"d":"2.86"},{"v":4.0134651892822e-05,"d":"0.00"},{"v":0.00122539561008543,"d":"0.00"},"up","yes"]
[37939,"j","chr12","-",6638075,6639278,"MSTRG.3058.3",3,766,"MSTRG.3058","ACRBP","NA","NA","NA","NA","NA",{"v":1.444844,"d":"1.44"},{"v":11.681571,"d":"11.68"},{"v":0.123685761101824,"d":"0.12"},{"v":-3.01524867032228,"d":"-3.02"},{"v":4.0556423974609e-05,"d":"0.00"},{"v":0.00123588262742521,"d":"0.00"},"down","yes"]
[182101,0,"chr8","+",22605038,22620471,"ENST00000389279",21,3980,"MSTRG.14220","CCAR2","GO:0003723(RNA binding);GO:0006397(mRNA processing);GO:0008380(RNA splicing);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005654(nucleoplasm);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0000790(nuclear chromatin);GO:0005515(protein binding);GO:0005681(spliceosomal complex);GO:0006974(cellular response to DNA damage stimulus);GO:0007049(cell cycle);GO:0048511(rhythmic process);GO:0006915(apoptotic process);GO:0016055(Wnt signaling pathway);GO:0005759(mitochondrial matrix);GO:0043065(positive regulation of apoptotic process);GO:0044609(DBIRD complex);GO:0031647(regulation of protein stability);GO:0032435(negative regulation of proteasomal ubiquitin-dependent protein catabolic process);GO:0090263(positive regulation of canonical Wnt signaling pathway);GO:0019899(enzyme binding);GO:0030308(negative regulation of cell growth);GO:0009411(response to UV);GO:0045892(negative regulation of transcription, DNA-templated);GO:0043653(mitochondrial fragmentation involved in apoptotic process);GO:0004857(enzyme inhibitor activity);GO:0043086(negative regulation of catalytic activity);GO:0042752(regulation of circadian rhythm);GO:1900034(regulation of cellular response to heat);GO:0000993(RNA polymerase II core binding);GO:0032784(regulation of DNA-templated transcription, elongation);GO:0090311(regulation of protein deacetylation);GO:1902230(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage);GO:2000003(positive regulation of DNA damage checkpoint)","NA","NA","NA","cell cycle and apoptosis regulator 2 [Source:HGNC Symbol;Acc:HGNC:23360]",{"v":7.058712,"d":"7.06"},{"v":0.988245,"d":"0.99"},{"v":7.14267413445046,"d":"7.14"},{"v":2.83646430369868,"d":"2.84"},{"v":4.06019132407321E-5,"d":"0.00"},{"v":0.00123588262742521,"d":"0.00"},"up","yes"]
[47010,0,"chr12","-",113319974,113335143,"ENST00000548477",5,2053,"MSTRG.3761","SLC8B1","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0055085(transmembrane transport);GO:0005743(mitochondrial inner membrane);GO:0005739(mitochondrion);GO:0006811(ion transport);GO:0015297(antiporter activity);GO:0006814(sodium ion transport);GO:0006816(calcium ion transport);GO:0050896(response to stimulus);GO:0005886(plasma membrane);GO:0042803(protein homodimerization activity);GO:0086036(regulation of cardiac muscle cell membrane potential);GO:0050796(regulation of insulin secretion);GO:0042593(glucose homeostasis);GO:0006851(mitochondrial calcium ion transmembrane transport);GO:0051560(mitochondrial calcium ion homeostasis);GO:0099093(mitochondrial calcium release);GO:0051480(regulation of cytosolic calcium ion concentration);GO:0005432(calcium:sodium antiporter activity);GO:2001256(regulation of store-operated calcium entry);GO:0032592(integral component of mitochondrial membrane);GO:0015368(calcium:cation antiporter activity);GO:0042802(identical protein binding);GO:0086038(calcium:sodium antiporter activity involved in regulation of cardiac muscle cell membrane potential);GO:0035725(sodium ion transmembrane transport);GO:0070588(calcium ion transmembrane transport);GO:1901623(regulation of lymphocyte chemotaxis);GO:0030061(mitochondrial crista);GO:0042383(sarcolemma)","NA","NA","NA","solute carrier family 8 member B1 [Source:HGNC Symbol;Acc:HGNC:26175]",{"v":3.848687,"d":"3.85"},{"v":0.512333,"d":"0.51"},{"v":7.51208100981198,"d":"7.51"},{"v":2.9092126210087,"d":"2.91"},{"v":4.06926919153278e-05,"d":"0.00"},{"v":1.23676053602019E-3,"d":"0.00"},"up","yes"]
[18846,0,"chr10","+",17228259,17237592,"ENST00000544301",10,2135,"MSTRG.1597","VIM","GO:0005737(cytoplasm);GO:0005198(structural molecule activity);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0005882(intermediate filament);GO:0005925(focal adhesion);GO:0005777(peroxisome);GO:0042802(identical protein binding);GO:0005200(structural constituent of cytoskeleton);GO:0070062(extracellular exosome);GO:0016032(viral process);GO:0031012(extracellular matrix);GO:0008022(protein C-terminus binding);GO:0097110(scaffold protein binding);GO:0006928(movement of cell or subcellular component);GO:0030049(muscle filament sliding);GO:0003725(double-stranded RNA binding);GO:0005212(structural constituent of eye lens);GO:1990254(keratin filament binding);GO:0010628(positive regulation of gene expression);GO:0010977(negative regulation of neuron projection development);GO:0014002(astrocyte development);GO:0045103(intermediate filament-based process);GO:0045109(intermediate filament organization);GO:0060020(Bergmann glial cell differentiation);GO:0060395(SMAD protein signal transduction);GO:0070307(lens fiber cell development);GO:0031252(cell leading edge);GO:0042995(cell projection);GO:0043005(neuron projection)","05206(MicroRNAs in cancer);05169(Epstein-Barr virus infection)","K07606","NA","vimentin [Source:HGNC Symbol;Acc:HGNC:12692]",{"v":8.909367,"d":"8.91"},{"v":68.096512,"d":"68.10"},{"v":0.130834410432064,"d":"0.13"},{"v":-2.9341860645194,"d":"-2.93"},{"v":4.10221947727062e-05,"d":"0.00"},{"v":0.00124408197792089,"d":"0.00"},"down","yes"]
[69058,0,"chr16","+",4425805,4456772,"ENST00000431375",9,2294,"MSTRG.5615","DNAJA3","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0043231(intracellular membrane-bounded organelle);GO:0046872(metal ion binding);GO:0005524(ATP binding);GO:0005739(mitochondrion);GO:0005829(cytosol);GO:0006457(protein folding);GO:0005886(plasma membrane);GO:0050790(regulation of catalytic activity);GO:0005515(protein binding);GO:0006915(apoptotic process);GO:0030054(cell junction);GO:0045202(synapse);GO:0045211(postsynaptic membrane);GO:0005759(mitochondrial matrix);GO:0051082(unfolded protein binding);GO:0031072(heat shock protein binding);GO:0009408(response to heat);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0008285(negative regulation of cell proliferation);GO:0042645(mitochondrial nucleoid);GO:0005884(actin filament);GO:0071340(skeletal muscle acetylcholine-gated channel clustering);GO:0031594(neuromuscular junction);GO:0019897(extrinsic component of plasma membrane);GO:0030544(Hsp70 protein binding);GO:0030695(GTPase regulator activity);GO:0006264(mitochondrial DNA replication);GO:0006924(activation-induced cell death of T cells);GO:0007005(mitochondrion organization);GO:0007264(small GTPase mediated signal transduction);GO:0007528(neuromuscular junction development);GO:0007569(cell aging);GO:0033077(T cell differentiation in thymus);GO:0042102(positive regulation of T cell proliferation);GO:0043069(negative regulation of programmed cell death);GO:0005634(nucleus)","05203(Viral carcinogenesis)","K09504","NA","DnaJ heat shock protein family (Hsp40) member A3 [Source:HGNC Symbol;Acc:HGNC:11808]",{"v":2.376593,"d":"2.38"},{"v":0.313055,"d":"0.31"},{"v":7.59161489195189,"d":"7.59"},{"v":2.92440680906568,"d":"2.92"},{"v":4.10581942833468e-05,"d":"0.00"},{"v":0.00124408197792089,"d":"0.00"},"up","yes"]
[136793,0,"chr3","+",51385409,51389344,"ENST00000470900",3,1509,"MSTRG.10954","MANF","GO:0005615(extracellular space);GO:0005783(endoplasmic reticulum);GO:0048471(perinuclear region of cytoplasm)","NA","NA","NA","mesencephalic astrocyte derived neurotrophic factor [Source:HGNC Symbol;Acc:HGNC:15461]",{"v":3.436481,"d":"3.44"},{"v":0.450988,"d":"0.45"},{"v":7.61989454264859,"d":"7.62"},{"v":2.92977103133399,"d":"2.93"},{"v":4.17932022343651e-05,"d":"0.00"},{"v":0.00126443433669061,"d":"0.00"},"up","yes"]
[15146,0,"chr1","+",204516379,204558119,"ENST00000391947",10,10008,"ENSG00000198625","MDM4","GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0043066(negative regulation of apoptotic process);GO:0016567(protein ubiquitination);GO:0008270(zinc ion binding);GO:0005515(protein binding);GO:0071157(negative regulation of cell cycle arrest);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0061630(ubiquitin protein ligase activity);GO:0006977(DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest);GO:0005654(nucleoplasm);GO:0050821(protein stabilization);GO:0016579(protein deubiquitination);GO:0008283(cell proliferation);GO:0019899(enzyme binding);GO:1901796(regulation of signal transduction by p53 class mediator);GO:0008285(negative regulation of cell proliferation);GO:0042177(negative regulation of protein catabolic process);GO:0006461(protein complex assembly);GO:0030330(DNA damage response, signal transduction by p53 class mediator);GO:0045023(G0 to G1 transition);GO:0071456(cellular response to hypoxia)","04115(p53 signaling pathway);05206(MicroRNAs in cancer)","K10127","NA","MDM4, p53 regulator [Source:HGNC Symbol;Acc:HGNC:6974]",{"v":0.166317,"d":"0.17"},{"v":1.313421,"d":"1.31"},{"v":0.126628857007768,"d":"0.13"},{"v":-2.98132188192228,"d":"-2.98"},{"v":4.20263005203252e-05,"d":"0.00"},{"v":1.26775006938763E-3,"d":"0.00"},"down","yes"]
[12977,0,"chr1","-",161541855,161549898,"ENST00000426740",5,2081,"MSTRG.1160","FCGR3A","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005886(plasma membrane);GO:0005576(extracellular region);GO:0038096(Fc-gamma receptor signaling pathway involved in phagocytosis);GO:0050776(regulation of immune response);GO:0070062(extracellular exosome);GO:0006955(immune response);GO:0019864(IgG binding);GO:0009897(external side of plasma membrane)","04145(Phagosome);04650(Natural killer cell mediated cytotoxicity);04666(Fc gamma R-mediated phagocytosis);04380(Osteoclast differentiation);05322(Systemic lupus erythematosus);05150(Staphylococcus aureus infection);05152(Tuberculosis);05140(Leishmaniasis)","K06463","NA","Fc fragment of IgG receptor IIIa [Source:HGNC Symbol;Acc:HGNC:3619]",{"v":5.118517,"d":"5.12"},{"v":0.701446,"d":"0.70"},{"v":7.297093432709,"d":"7.30"},{"v":2.86732192628876,"d":"2.87"},{"v":4.20297749366291e-05,"d":"0.00"},{"v":1.26775006938763E-3,"d":"0.00"},"up","yes"]
[35949,"j","chr11","+",119067801,119081972,"MSTRG.2926.3",15,2950,"MSTRG.2926","VPS11","NA","NA","NA","NA","NA",{"v":12.878469,"d":"12.88"},{"v":1.815059,"d":"1.82"},{"v":7.09534455904739,"d":"7.10"},{"v":2.82687274511162,"d":"2.83"},{"v":4.22982048461733e-05,"d":"0.00"},{"v":0.00127259902707869,"d":"0.00"},"up","yes"]
[185777,0,"chr8","-",96231297,96235545,"ENST00000519322",3,750,"MSTRG.14455","UQCRB","GO:0016020(membrane);GO:0055114(oxidation-reduction process);GO:0005743(mitochondrial inner membrane);GO:0005739(mitochondrion);GO:0005515(protein binding);GO:1902600(hydrogen ion transmembrane transport);GO:0070469(respiratory chain);GO:0008121(ubiquinol-cytochrome-c reductase activity);GO:0006122(mitochondrial electron transport, ubiquinol to cytochrome c);GO:0005750(mitochondrial respiratory chain complex III);GO:0009060(aerobic respiration);GO:0006119(oxidative phosphorylation);GO:0005746(mitochondrial respiratory chain);GO:0034551(mitochondrial respiratory chain complex III assembly)","00190(Oxidative phosphorylation);04260(Cardiac muscle contraction);05010(Alzheimer's disease);05012(Parkinson's disease);05016(Huntington's disease);04932(Non-alcoholic fatty liver disease (NAFLD))","NA","NA","ubiquinol-cytochrome c reductase binding protein [Source:HGNC Symbol;Acc:HGNC:12582]",{"v":14.869716,"d":"14.87"},{"v":2.024036,"d":"2.02"},{"v":7.34656695829521,"d":"7.35"},{"v":2.87707023780088,"d":"2.88"},{"v":4.23179964934019e-05,"d":"0.00"},{"v":0.00127259902707869,"d":"0.00"},"up","yes"]
[37830,0,"chr12","+",6452084,6462318,"ENST00000266556",7,1741,"MSTRG.3050","TAPBPL","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005794(Golgi apparatus);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0000139(Golgi membrane);GO:0002376(immune system process);GO:0043231(intracellular membrane-bounded organelle);GO:0031090(organelle membrane);GO:0032403(protein complex binding);GO:0002590(negative regulation of antigen processing and presentation of peptide antigen via MHC class I)","NA","NA","NA","TAP binding protein like [Source:HGNC Symbol;Acc:HGNC:30683]",{"v":0.464988,"d":"0.46"},{"v":3.761178,"d":"3.76"},{"v":0.123628288796755,"d":"0.12"},{"v":-3.01591919438704,"d":"-3.02"},{"v":4.24681421304796E-5,"d":"0.00"},{"v":0.00127519377753596,"d":"0.00"},"down","yes"]
[43398,"j","chr12","-",57472259,57477927,"MSTRG.3490.5",14,2176,"MSTRG.3490","ARHGAP9","NA","NA","NA","NA","NA",{"v":1.527698,"d":"1.53"},{"v":11.822152,"d":"11.82"},{"v":0.129223342755194,"d":"0.13"},{"v":-2.95206139455107,"d":"-2.95"},{"v":4.25642612903371e-05,"d":"0.00"},{"v":1.27616091508326E-3,"d":"0.00"},"down","yes"]
[127461,0,"chr21","+",42219118,42297244,"ENST00000361802",15,3034,"ENSG00000160179","ABCG1","GO:0042632(cholesterol homeostasis);GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0005794(Golgi apparatus);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005739(mitochondrion);GO:0005886(plasma membrane);GO:0000139(Golgi membrane);GO:0006869(lipid transport);GO:0016887(ATPase activity);GO:0005887(integral component of plasma membrane);GO:0055085(transmembrane transport);GO:0042803(protein homodimerization activity);GO:0046982(protein heterodimerization activity);GO:0009897(external side of plasma membrane);GO:0010033(response to organic substance);GO:1901998(toxin transport);GO:0033344(cholesterol efflux);GO:0046983(protein dimerization activity);GO:0006355(regulation of transcription, DNA-templated);GO:0019534(toxin transporter activity);GO:0015485(cholesterol binding);GO:0008203(cholesterol metabolic process);GO:0005543(phospholipid binding);GO:0034375(high-density lipoprotein particle remodeling);GO:0043691(reverse cholesterol transport);GO:0005548(phospholipid transporter activity);GO:0017127(cholesterol transporter activity);GO:0010745(negative regulation of macrophage derived foam cell differentiation);GO:0010887(negative regulation of cholesterol storage);GO:0032367(intracellular cholesterol transport);GO:0033700(phospholipid efflux);GO:0055091(phospholipid homeostasis);GO:0043531(ADP binding);GO:0034374(low-density lipoprotein particle remodeling);GO:0055037(recycling endosome);GO:0045542(positive regulation of cholesterol biosynthetic process);GO:0005768(endosome);GO:0033993(response to lipid);GO:0034041(sterol-transporting ATPase activity);GO:0034437(glycoprotein transporter activity);GO:0009720(detection of hormone stimulus);GO:0010872(regulation of cholesterol esterification);GO:0034436(glycoprotein transport);GO:0042987(amyloid precursor protein catabolic process);GO:0010875(positive regulation of cholesterol efflux);GO:0010888(negative regulation of lipid storage);GO:0030301(cholesterol transport);GO:0055099(response to high density lipoprotein particle)","02010(ABC transporters)","K05679","NA","ATP binding cassette subfamily G member 1 [Source:HGNC Symbol;Acc:HGNC:73]",{"v":0.611827,"d":"0.61"},{"v":4.785709,"d":"4.79"},{"v":0.12784458896268,"d":"0.13"},{"v":-2.96753699525352,"d":"-2.97"},{"v":4.33973173277364e-05,"d":"0.00"},{"v":1.29918685517277E-3,"d":"0.00"},"down","yes"]
[116551,"j","chr2","-",174559574,174682957,"MSTRG.9248.4",9,4965,"MSTRG.9248","WIPF1","NA","NA","NA","NA","NA",{"v":4.236777,"d":"4.24"},{"v":32.104553,"d":"32.10"},{"v":0.131968104337101,"d":"0.13"},{"v":-2.92173881132683,"d":"-2.92"},{"v":4.36381576435541e-05,"d":"0.00"},{"v":1.30205269234861E-3,"d":"0.00"},"down","yes"]
[188404,0,"chr8","-",144451120,144457928,"ENST00000533173",2,6158,"MSTRG.14638","CYHR1","GO:0005737(cytoplasm);GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0005654(nucleoplasm);GO:0005515(protein binding);GO:0048471(perinuclear region of cytoplasm);GO:0016020(membrane);GO:0016021(integral component of membrane)","NA","NA","NA","cysteine and histidine rich 1 [Source:HGNC Symbol;Acc:HGNC:17806]",{"v":0.96377,"d":"0.96"},{"v":0.127842,"d":"0.13"},{"v":7.53875878036952,"d":"7.54"},{"v":2.91432701038883,"d":"2.91"},{"v":4.36706279372573E-5,"d":"0.00"},{"v":1.30205269234861E-3,"d":"0.00"},"up","yes"]
[103932,0,"chr19","+",49496434,49499689,"ENST00000594493",5,575,"MSTRG.8312","RPS11","GO:0003723(RNA binding);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0006412(translation);GO:0030529(intracellular ribonucleoprotein complex);GO:0005622(intracellular);GO:0003735(structural constituent of ribosome);GO:0005840(ribosome);GO:0005515(protein binding);GO:0022627(cytosolic small ribosomal subunit);GO:0005730(nucleolus);GO:0005925(focal adhesion);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0031012(extracellular matrix);GO:0019843(rRNA binding);GO:0006413(translational initiation);GO:0006364(rRNA processing);GO:0000184(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay);GO:0019083(viral transcription);GO:0006614(SRP-dependent cotranslational protein targeting to membrane);GO:0001649(osteoblast differentiation)","03010(Ribosome)","NA","NA","ribosomal protein S11 [Source:HGNC Symbol;Acc:HGNC:10384]",{"v":28.779518,"d":"28.78"},{"v":4.014536,"d":"4.01"},{"v":7.16882797912386,"d":"7.17"},{"v":2.84173727416887,"d":"2.84"},{"v":4.3688667060976e-05,"d":"0.00"},{"v":1.30205269234861E-3,"d":"0.00"},"up","yes"]
[183368,0,"chr8","-",41929479,42051987,"ENST00000406337",18,9241,"MSTRG.14327","KAT6A","GO:0005634(nucleus);GO:0016607(nuclear speck);GO:0046872(metal ion binding);GO:0005730(nucleolus);GO:0005829(cytosol);GO:0016740(transferase activity);GO:0003713(transcription coactivator activity);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0016569(covalent chromatin modification);GO:0003677(DNA binding);GO:0016746(transferase activity, transferring acyl groups);GO:0006334(nucleosome assembly);GO:0000786(nucleosome);GO:0008270(zinc ion binding);GO:0005515(protein binding);GO:0016747(transferase activity, transferring acyl groups other than amino-acyl groups);GO:0004402(histone acetyltransferase activity);GO:0045893(positive regulation of transcription, DNA-templated);GO:0005654(nucleoplasm);GO:0070776(MOZ/MORF histone acetyltransferase complex);GO:0043966(histone H3 acetylation);GO:0048513(animal organ development);GO:0008134(transcription factor binding);GO:0045892(negative regulation of transcription, DNA-templated);GO:1901796(regulation of signal transduction by p53 class mediator);GO:0016605(PML body);GO:0006323(DNA packaging);GO:0090398(cellular senescence);GO:0030099(myeloid cell differentiation);GO:0016407(acetyltransferase activity);GO:0006473(protein acetylation);GO:0016573(histone acetylation)","04550(Signaling pathways regulating pluripotency of stem cells)","K11305","EC:2.3.1.48","lysine acetyltransferase 6A [Source:HGNC Symbol;Acc:HGNC:13013]",{"v":4.019797,"d":"4.02"},{"v":0.568708,"d":"0.57"},{"v":7.06829691159611,"d":"7.07"},{"v":2.82136264315643,"d":"2.82"},{"v":4.37592343164698e-05,"d":"0.00"},{"v":0.00130221220690204,"d":"0.00"},"up","yes"]
[197897,"j","chrX","+",66015194,66020422,"MSTRG.15336.1",4,1930,"MSTRG.15336","AL034397.3","NA","NA","NA","NA","NA",{"v":1.550927,"d":"1.55"},{"v":11.975636,"d":"11.98"},{"v":0.1295068587589,"d":"0.13"},{"v":-2.94889958897999,"d":"-2.95"},{"v":4.39799136185574e-05,"d":"0.00"},{"v":0.00130683171895142,"d":"0.00"},"down","yes"]
[148025,0,"chr4","-",70655541,70666660,"ENST00000254801",4,1438,"MSTRG.11653","JCHAIN","GO:0042803(protein homodimerization activity);GO:0005576(extracellular region);GO:0006955(immune response);GO:0005615(extracellular space);GO:0045087(innate immune response);GO:0003823(antigen binding);GO:0002250(adaptive immune response);GO:0006898(receptor-mediated endocytosis);GO:0050900(leukocyte migration);GO:0031210(phosphatidylcholine binding);GO:0070062(extracellular exosome);GO:0001895(retina homeostasis);GO:0072562(blood microparticle);GO:0019731(antibacterial humoral response);GO:0032461(positive regulation of protein oligomerization);GO:0003697(single-stranded DNA binding);GO:0042834(peptidoglycan binding);GO:0034987(immunoglobulin receptor binding);GO:0019862(IgA binding);GO:0030674(protein binding, bridging);GO:0003094(glomerular filtration);GO:0060267(positive regulation of respiratory burst);GO:0071748(monomeric IgA immunoglobulin complex);GO:0071750(dimeric IgA immunoglobulin complex);GO:0071751(secretory IgA immunoglobulin complex);GO:0071752(secretory dimeric IgA immunoglobulin complex);GO:0071756(pentameric IgM immunoglobulin complex)","NA","NA","NA","joining chain of multimeric IgA and IgM [Source:HGNC Symbol;Acc:HGNC:5713]",{"v":64.020607,"d":"64.02"},{"v":9.164944,"d":"9.16"},{"v":6.985378961399,"d":"6.99"},{"v":2.80433838491185,"d":"2.80"},{"v":4.46490315231014e-05,"d":"0.00"},{"v":0.00132474273618616,"d":"0.00"},"up","yes"]
[181832,0,"chr8","+",20197367,20221701,"ENST00000276390",14,2875,"MSTRG.14206","ATP6V1B2","GO:0006810(transport);GO:0016020(membrane);GO:0043231(intracellular membrane-bounded organelle);GO:0005524(ATP binding);GO:0016787(hydrolase activity);GO:0005765(lysosomal membrane);GO:0005829(cytosol);GO:0015992(proton transport);GO:0006811(ion transport);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0042470(melanosome);GO:0015991(ATP hydrolysis coupled proton transport);GO:0016820(hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances);GO:0033180(proton-transporting V-type ATPase, V1 domain);GO:0046034(ATP metabolic process);GO:0001726(ruffle);GO:0005737(cytoplasm);GO:0005902(microvillus);GO:0016021(integral component of membrane);GO:0043209(myelin sheath);GO:0070062(extracellular exosome);GO:0034220(ion transmembrane transport);GO:0012505(endomembrane system);GO:0046961(proton-transporting ATPase activity, rotational mechanism);GO:0008286(insulin receptor signaling pathway);GO:0016241(regulation of macroautophagy);GO:0033572(transferrin transport);GO:0090383(phagosome acidification);GO:0015078(hydrogen ion transmembrane transporter activity)","00190(Oxidative phosphorylation);04150(mTOR signaling pathway);04145(Phagosome);04966(Collecting duct acid secretion);04721(Synaptic vesicle cycle);05323(Rheumatoid arthritis);05110(Vibrio cholerae infection);05120(Epithelial cell signaling in Helicobacter pylori infection)","K02147","NA","ATPase H+ transporting V1 subunit B2 [Source:HGNC Symbol;Acc:HGNC:854]",{"v":6.502536,"d":"6.50"},{"v":49.111275,"d":"49.11"},{"v":0.132404137339134,"d":"0.13"},{"v":-2.91697989097944,"d":"-2.92"},{"v":4.49022189613484E-5,"d":"0.00"},{"v":0.00133027820210713,"d":"0.00"},"down","yes"]
[46081,0,"chr12","-",105173296,105236238,"ENST00000258530",21,3239,"MSTRG.3668","APPL2","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005515(protein binding);GO:0007165(signal transduction);GO:0007049(cell cycle);GO:0005768(endosome);GO:0070062(extracellular exosome);GO:0008283(cell proliferation);GO:0010008(endosome membrane);GO:0031901(early endosome membrane);GO:0016581(NuRD complex)","NA","NA","NA","adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2 [Source:HGNC Symbol;Acc:HGNC:18242]",{"v":0.598481,"d":"0.60"},{"v":4.648206,"d":"4.65"},{"v":0.128755266010155,"d":"0.13"},{"v":-2.95729665605657,"d":"-2.96"},{"v":4.59309682039991E-5,"d":"0.00"},{"v":1.358347444013E-3,"d":"0.00"},"down","yes"]
[193132,0,"chr9","+",122371080,122393178,"ENST00000223423",11,2328,"MSTRG.14948","PTGS1","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005794(Golgi apparatus);GO:0043231(intracellular membrane-bounded organelle);GO:0046872(metal ion binding);GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0006629(lipid metabolic process);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0006631(fatty acid metabolic process);GO:0006633(fatty acid biosynthetic process);GO:0006954(inflammatory response);GO:0051213(dioxygenase activity);GO:0020037(heme binding);GO:0008217(regulation of blood pressure);GO:0098869(cellular oxidant detoxification);GO:0004601(peroxidase activity);GO:0006979(response to oxidative stress);GO:0004666(prostaglandin-endoperoxide synthase activity);GO:0001516(prostaglandin biosynthetic process);GO:0019371(cyclooxygenase pathway);GO:0070062(extracellular exosome);GO:0006805(xenobiotic metabolic process);GO:0031090(organelle membrane);GO:0006693(prostaglandin metabolic process);GO:0042127(regulation of cell proliferation);GO:0001750(photoreceptor outer segment)","00590(Arachidonic acid metabolism);04611(Platelet activation);04923(Regulation of lipolysis in adipocyte);04726(Serotonergic synapse)","K00509","EC:1.14.99.1","prostaglandin-endoperoxide synthase 1 [Source:HGNC Symbol;Acc:HGNC:9604]",{"v":21.891985,"d":"21.89"},{"v":3.128083,"d":"3.13"},{"v":6.99853072952348,"d":"7.00"},{"v":2.80705207466898,"d":"2.81"},{"v":4.59857207608566e-05,"d":"0.00"},{"v":1.358347444013E-3,"d":"0.00"},"up","yes"]
[109419,0,"chr2","-",46901874,46915868,"ENST00000319466",4,4182,"MSTRG.8673","MCFD2","GO:0006810(transport);GO:0015031(protein transport);GO:0046872(metal ion binding);GO:0005509(calcium ion binding);GO:0005794(Golgi apparatus);GO:0005783(endoplasmic reticulum);GO:0016192(vesicle-mediated transport);GO:0000139(Golgi membrane);GO:0005789(endoplasmic reticulum membrane);GO:0006888(ER to Golgi vesicle-mediated transport);GO:0048208(COPII vesicle coating);GO:0012507(ER to Golgi transport vesicle membrane);GO:0033116(endoplasmic reticulum-Golgi intermediate compartment membrane);GO:0005793(endoplasmic reticulum-Golgi intermediate compartment);GO:0018279(protein N-linked glycosylation via asparagine)","NA","NA","NA","multiple coagulation factor deficiency 2 [Source:HGNC Symbol;Acc:HGNC:18451]",{"v":4.991609,"d":"4.99"},{"v":0.704644,"d":"0.70"},{"v":7.08387355884674,"d":"7.08"},{"v":2.82453846143303,"d":"2.82"},{"v":4.6242245421163e-05,"d":"0.00"},{"v":1.36201756955614E-3,"d":"0.00"},"up","yes"]
[38180,0,"chr12","+",6951356,6961316,"ENST00000416215",15,2412,"MSTRG.3080","PTPN6","GO:0008284(positive regulation of cell proliferation);GO:0005737(cytoplasm);GO:0005634(nucleus);GO:0014068(positive regulation of phosphatidylinositol 3-kinase signaling);GO:0005730(nucleolus);GO:0016787(hydrolase activity);GO:0004725(protein tyrosine phosphatase activity);GO:0016791(phosphatase activity);GO:0006470(protein dephosphorylation);GO:0016311(dephosphorylation);GO:0035335(peptidyl-tyrosine dephosphorylation);GO:0004721(phosphoprotein phosphatase activity);GO:0005515(protein binding);GO:0030154(cell differentiation);GO:0050900(leukocyte migration);GO:0005576(extracellular region);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0019901(protein kinase binding);GO:0008285(negative regulation of cell proliferation);GO:0008283(cell proliferation);GO:0043234(protein complex);GO:0043312(neutrophil degranulation);GO:0007186(G-protein coupled receptor signaling pathway);GO:0006915(apoptotic process);GO:0030168(platelet activation);GO:0016020(membrane);GO:0035580(specific granule lumen);GO:1904724(tertiary granule lumen);GO:0031295(T cell costimulation);GO:0070372(regulation of ERK1 and ERK2 cascade);GO:0018108(peptidyl-tyrosine phosphorylation);GO:0060338(regulation of type I interferon-mediated signaling pathway);GO:0050732(negative regulation of peptidyl-tyrosine phosphorylation);GO:0005001(transmembrane receptor protein tyrosine phosphatase activity);GO:2000045(regulation of G1/S transition of mitotic cell cycle);GO:0001784(phosphotyrosine residue binding);GO:0017124(SH3 domain binding);GO:0042169(SH2 domain binding);GO:0050839(cell adhesion molecule binding);GO:0002244(hematopoietic progenitor cell differentiation);GO:0002924(negative regulation of humoral immune response mediated by circulating immunoglobulin);GO:0030220(platelet formation);GO:0033277(abortive mitotic cell cycle);GO:0033630(positive regulation of cell adhesion mediated by integrin);GO:0035556(intracellular signal transduction);GO:0035855(megakaryocyte development);GO:0042130(negative regulation of T cell proliferation);GO:0042267(natural killer cell mediated cytotoxicity);GO:0043407(negative regulation of MAP kinase activity);GO:0043409(negative regulation of MAPK cascade);GO:0045577(regulation of B cell differentiation);GO:0050853(B cell receptor signaling pathway);GO:0050859(negative regulation of B cell receptor signaling pathway);GO:0050860(negative regulation of T cell receptor signaling pathway);GO:0051279(regulation of release of sequestered calcium ion into cytosol);GO:0070527(platelet aggregation);GO:0005911(cell-cell junction);GO:0042105(alpha-beta T cell receptor complex)","04630(Jak-STAT signaling pathway);04520(Adherens junction);04650(Natural killer cell mediated cytotoxicity);04660(T cell receptor signaling pathway);04662(B cell receptor signaling pathway);05205(Proteoglycans in cancer);05140(Leishmaniasis)","NA","NA","protein tyrosine phosphatase, non-receptor type 6 [Source:HGNC Symbol;Acc:HGNC:9658]",{"v":0.827817,"d":"0.83"},{"v":6.414324,"d":"6.41"},{"v":0.129057559300091,"d":"0.13"},{"v":-2.95391344787349,"d":"-2.95"},{"v":4.6246389831684E-5,"d":"0.00"},{"v":1.36201756955614E-3,"d":"0.00"},"down","yes"]
[128087,0,"chr21","+",46459057,46547205,"ENST00000435722",21,2760,"ENSG00000160305","DIP2A","GO:0005634(nucleus);GO:0003824(catalytic activity);GO:0008152(metabolic process);GO:0005515(protein binding);GO:0007275(multicellular organism development);GO:0042981(regulation of apoptotic process);GO:0010629(negative regulation of gene expression);GO:0009986(cell surface)","NA","NA","NA","disco interacting protein 2 homolog A [Source:HGNC Symbol;Acc:HGNC:17217]",{"v":2.875488,"d":"2.88"},{"v":0.38877,"d":"0.39"},{"v":7.39637317694266,"d":"7.40"},{"v":2.88681801637848,"d":"2.89"},{"v":4.65470418207627E-5,"d":"0.00"},{"v":1.36885321218997E-3,"d":"0.00"},"up","yes"]
[14966,0,"chr1","-",202878957,202889135,"ENST00000367262",2,2430,"MSTRG.1301","RABIF","GO:0006810(transport);GO:0015031(protein transport);GO:0007264(small GTPase mediated signal transduction);GO:0046872(metal ion binding);GO:0008270(zinc ion binding);GO:0043547(positive regulation of GTPase activity);GO:0005515(protein binding);GO:0005085(guanyl-nucleotide exchange factor activity);GO:0016020(membrane);GO:0005829(cytosol);GO:0061025(membrane fusion);GO:0006892(post-Golgi vesicle-mediated transport)","NA","NA","NA","RAB interacting factor [Source:HGNC Symbol;Acc:HGNC:9797]",{"v":2.383778,"d":"2.38"},{"v":0.316289,"d":"0.32"},{"v":7.53670851657819,"d":"7.54"},{"v":2.91393459728955,"d":"2.91"},{"v":4.70538469664215e-05,"d":"0.00"},{"v":1.38172237680221E-3,"d":"0.00"},"up","yes"]
[189944,0,"chr9","-",35056870,35072549,"ENST00000493886",16,2942,"MSTRG.14743","VCP","GO:0003723(RNA binding);GO:0006810(transport);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0016787(hydrolase activity);GO:0016567(protein ubiquitination);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005515(protein binding);GO:0006281(DNA repair);GO:0006974(cellular response to DNA damage stimulus);GO:0006914(autophagy);GO:0005576(extracellular region);GO:0042802(identical protein binding);GO:0008289(lipid binding);GO:0018279(protein N-linked glycosylation via asparagine);GO:0030970(retrograde protein transport, ER to cytosol);GO:0043231(intracellular membrane-bounded organelle);GO:0070062(extracellular exosome);GO:0016579(protein deubiquitination);GO:0055085(transmembrane transport);GO:0043234(protein complex);GO:0016887(ATPase activity);GO:0006457(protein folding);GO:0043312(neutrophil degranulation);GO:0030433(ubiquitin-dependent ERAD pathway);GO:0042981(regulation of apoptotic process);GO:0019904(protein domain specific binding);GO:0034774(secretory granule lumen);GO:1904813(ficolin-1-rich granule lumen);GO:0043161(proteasome-mediated ubiquitin-dependent protein catabolic process);GO:0048471(perinuclear region of cytoplasm);GO:0035578(azurophil granule lumen);GO:0032436(positive regulation of proteasomal ubiquitin-dependent protein catabolic process);GO:0006919(activation of cysteine-type endopeptidase activity involved in apoptotic process);GO:0019903(protein phosphatase binding);GO:0045732(positive regulation of protein catabolic process);GO:0031625(ubiquitin protein ligase binding);GO:0035861(site of double-strand break);GO:0045184(establishment of protein localization);GO:1904288(BAT3 complex binding);GO:1990381(ubiquitin-specific protease binding);GO:0036503(ERAD pathway);GO:0006479(protein methylation);GO:0006302(double-strand break repair);GO:0032510(endosome to lysosome transport via multivesicular body sorting pathway);GO:0030968(endoplasmic reticulum unfolded protein response);GO:0097352(autophagosome maturation);GO:0031334(positive regulation of protein complex assembly);GO:0000502(proteasome complex);GO:0070987(error-free translesion synthesis);GO:0019985(translesion synthesis);GO:0010498(proteasomal protein catabolic process);GO:0019079(viral genome replication);GO:0061857(endoplasmic reticulum stress-induced pre-emptive quality control);GO:0005102(receptor binding);GO:0031593(polyubiquitin binding);GO:0032403(protein complex binding);GO:0035800(deubiquitinase activator activity);GO:0036435(K48-linked polyubiquitin binding);GO:0042288(MHC class I protein binding);GO:0043531(ADP binding);GO:0044389(ubiquitin-like protein ligase binding);GO:0006511(ubiquitin-dependent protein catabolic process);GO:0006734(NADH metabolic process);GO:0006888(ER to Golgi vesicle-mediated transport);GO:0010918(positive regulation of mitochondrial membrane potential);GO:0016236(macroautophagy);GO:0034214(protein hexamerization);GO:0046034(ATP metabolic process);GO:0051260(protein homooligomerization);GO:0070842(aggresome assembly);GO:0071712(ER-associated misfolded protein catabolic process);GO:0072389(flavin adenine dinucleotide catabolic process);GO:1903006(positive regulation of protein K63-linked deubiquitination);GO:1903007(positive regulation of Lys63-specific deubiquitinase activity);GO:1903715(regulation of aerobic respiration);GO:1903862(positive regulation of oxidative phosphorylation);GO:2000158(positive regulation of ubiquitin-specific protease activity);GO:2001171(positive regulation of ATP biosynthetic process);GO:0005811(lipid particle);GO:0034098(VCP-NPL4-UFD1 AAA ATPase complex);GO:0036513(Derlin-1 retrotranslocation complex);GO:0043209(myelin sheath);GO:1904949(ATPase complex);GO:1990730(VCP-NSFL1C complex)","04141(Protein processing in endoplasmic reticulum);05134(Legionellosis)","NA","NA","valosin containing protein [Source:HGNC Symbol;Acc:HGNC:12666]",{"v":5.947533,"d":"5.95"},{"v":0.840173,"d":"0.84"},{"v":7.07893850433185,"d":"7.08"},{"v":2.82353304260356,"d":"2.82"},{"v":4.71423118165167e-05,"d":"0.00"},{"v":0.00138228734559795,"d":"0.00"},"up","yes"]
[195100,0,"chr9","-",137204082,137205638,"ENST00000343666",1,1557,"MSTRG.15124","TMEM203","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0007283(spermatogenesis);GO:0005515(protein binding);GO:0006874(cellular calcium ion homeostasis)","NA","NA","NA","transmembrane protein 203 [Source:HGNC Symbol;Acc:HGNC:28217]",{"v":7.388533,"d":"7.39"},{"v":1.02702,"d":"1.03"},{"v":7.19414714416467,"d":"7.19"},{"v":2.84682366767258,"d":"2.85"},{"v":4.72290387037969E-5,"d":"0.00"},{"v":1.38279977248888E-3,"d":"0.00"},"up","yes"]
[72873,0,"chr16","+",50287912,50318132,"ENST00000254235",25,6138,"MSTRG.5912","ADCY7","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:1902600(hydrogen ion transmembrane transport);GO:0022904(respiratory electron transport chain);GO:0004129(cytochrome-c oxidase activity);GO:0005622(intracellular);GO:0035556(intracellular signal transduction);GO:0016849(phosphorus-oxygen lyase activity);GO:0009190(cyclic nucleotide biosynthetic process);GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0016829(lyase activity);GO:0005886(plasma membrane);GO:0004016(adenylate cyclase activity);GO:0006171(cAMP biosynthetic process);GO:0007165(signal transduction);GO:0007193(adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway);GO:0004383(guanylate cyclase activity);GO:0003091(renal water homeostasis);GO:0006182(cGMP biosynthetic process);GO:0007189(adenylate cyclase-activating G-protein coupled receptor signaling pathway);GO:0007190(activation of adenylate cyclase activity);GO:0034199(activation of protein kinase A activity);GO:0071377(cellular response to glucagon stimulus);GO:0008074(guanylate cyclase complex, soluble);GO:0030819(positive regulation of cAMP biosynthetic process);GO:0071361(cellular response to ethanol);GO:0060135(maternal process involved in female pregnancy)","00230(Purine metabolism);04015(Rap1 signaling pathway);04371(Apelin signaling pathway);04020(Calcium signaling pathway);04072(Phospholipase D signaling pathway);04024(cAMP signaling pathway);04022(cGMP - PKG signaling pathway);04114(Oocyte meiosis);04540(Gap junction);04611(Platelet activation);04062(Chemokine signaling pathway);04911(Insulin secretion);04923(Regulation of lipolysis in adipocyte);04912(GnRH signaling pathway);04913(Ovarian Steroidogenesis);04915(Estrogen signaling pathway);04914(Progesterone-mediated oocyte maturation);04921(Oxytocin signaling pathway);04926(Relaxin signaling pathway);04918(Thyroid hormone synthesis);04916(Melanogenesis);04925(Aldosterone synthesis and secretion);04927(Cortisol synthesis and secretion);04261(Adrenergic signaling in cardiomyocytes);04270(Vascular smooth muscle contraction);04970(Salivary secretion);04971(Gastric acid secretion);04972(Pancreatic secretion);04976(Bile secretion);04724(Glutamatergic synapse);04727(GABAergic synapse);04725(Cholinergic synapse);04723(Retrograde endocannabinoid signaling);04750(Inflammatory mediator regulation of TRP channels);04211(Longevity regulating pathway - mammal);04213(Longevity regulating pathway - multiple species);04713(Circadian entrainment);05200(Pathways in cancer);05032(Morphine addiction);05414(Dilated cardiomyopathy (DCM));05166(HTLV-I infection);01522(Endocrine resistance)","K08047","EC:4.6.1.1","adenylate cyclase 7 [Source:HGNC Symbol;Acc:HGNC:238]",{"v":0.87018,"d":"0.87"},{"v":6.58924,"d":"6.59"},{"v":0.13206075359222,"d":"0.13"},{"v":-2.92072631119759,"d":"-2.92"},{"v":4.77237157304322e-05,"d":"0.00"},{"v":1.3952374168452E-3,"d":"0.00"},"down","yes"]
[6214,0,"chr1","-",53214099,53220617,"ENST00000294360",8,1085,"MSTRG.578","C1orf123","GO:0003674(molecular_function);GO:0008150(biological_process);GO:0070062(extracellular exosome)","NA","NA","NA","chromosome 1 open reading frame 123 [Source:HGNC Symbol;Acc:HGNC:26059]",{"v":11.061398,"d":"11.06"},{"v":1.545513,"d":"1.55"},{"v":7.15710446951918,"d":"7.16"},{"v":2.83937603827659,"d":"2.84"},{"v":4.80233950073671e-05,"d":"0.00"},{"v":1.40070346161032E-3,"d":"0.00"},"up","yes"]
[104861,0,"chr19","-",52154848,52171491,"ENST00000597252",5,3209,"ENSG00000196267","ZNF836","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0005622(intracellular);GO:0003700(transcription factor activity, sequence-specific DNA binding)","NA","NA","NA","zinc finger protein 836 [Source:HGNC Symbol;Acc:HGNC:34333]",{"v":0.198384,"d":"0.20"},{"v":1.621993,"d":"1.62"},{"v":0.122308789248782,"d":"0.12"},{"v":-3.03140001358941,"d":"-3.03"},{"v":4.8050975120346e-05,"d":"0.00"},{"v":1.40070346161032E-3,"d":"0.00"},"down","yes"]
[64321,0,"chr15","-",72340919,72376476,"ENST00000268097",14,5252,"MSTRG.5266","HEXA","GO:0016020(membrane);GO:0016787(hydrolase activity);GO:0005975(carbohydrate metabolic process);GO:0008152(metabolic process);GO:0004553(hydrolase activity, hydrolyzing O-glycosyl compounds);GO:0016798(hydrolase activity, acting on glycosyl bonds);GO:0005764(lysosome);GO:0004563(beta-N-acetylhexosaminidase activity);GO:0006687(glycosphingolipid metabolic process);GO:0070062(extracellular exosome);GO:0102148(-);GO:0042582(azurophil granule);GO:0043202(lysosomal lumen);GO:0030207(chondroitin sulfate catabolic process);GO:0046982(protein heterodimerization activity);GO:0042340(keratan sulfate catabolic process);GO:0030214(hyaluronan catabolic process);GO:0006024(glycosaminoglycan biosynthetic process);GO:0008375(acetylglucosaminyltransferase activity)","00520(Amino sugar and nucleotide sugar metabolism);00531(Glycosaminoglycan degradation);00603(Glycosphingolipid biosynthesis - globo and isoglobo series);00604(Glycosphingolipid biosynthesis - ganglio series);00511(Other glycan degradation);04142(Lysosome)","K12373","EC:3.2.1.52","hexosaminidase subunit alpha [Source:HGNC Symbol;Acc:HGNC:4878]",{"v":5.620991,"d":"5.62"},{"v":0.804864,"d":"0.80"},{"v":6.98377738350827,"d":"6.98"},{"v":2.80400757202185,"d":"2.80"},{"v":4.83093666707741e-05,"d":"0.00"},{"v":0.00140618284793297,"d":"0.00"},"up","yes"]
[4911,0,"chr1","+",42683156,42697211,"ENST00000467957",5,770,"MSTRG.472","YBX1","GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0006397(mRNA processing);GO:0008380(RNA splicing);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0043231(intracellular membrane-bounded organelle);GO:0005829(cytosol);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0031965(nuclear membrane);GO:0030529(intracellular ribonucleoprotein complex);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:0005654(nucleoplasm);GO:0070062(extracellular exosome);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0010494(cytoplasmic stress granule);GO:0006366(transcription from RNA polymerase II promoter);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:1903608(protein localization to cytoplasmic stress granule);GO:0001077(transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0051781(positive regulation of cell division);GO:0000398(mRNA splicing, via spliceosome);GO:0070934(CRD-mediated mRNA stabilization);GO:0070937(CRD-mediated mRNA stability complex);GO:0071204(histone pre-mRNA 3'end processing complex);GO:0051020(GTPase binding);GO:0005689(U12-type spliceosomal complex);GO:0003690(double-stranded DNA binding);GO:0003697(single-stranded DNA binding);GO:0003682(chromatin binding);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0001701(in utero embryonic development);GO:0051154(negative regulation of striated muscle cell differentiation)","NA","NA","NA","Y-box binding protein 1 [Source:HGNC Symbol;Acc:HGNC:8014]",{"v":50.372494,"d":"50.37"},{"v":7.233791,"d":"7.23"},{"v":6.96349866895519,"d":"6.96"},{"v":2.79981234114997,"d":"2.80"},{"v":4.8410178909367e-05,"d":"0.00"},{"v":0.00140706616078929,"d":"0.00"},"up","yes"]
[177579,0,"chr7","-",106248285,106285192,"ENST00000222553",11,4582,"MSTRG.13893","NAMPT","GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016607(nuclear speck);GO:0016740(transferase activity);GO:0016757(transferase activity, transferring glycosyl groups);GO:0030054(cell junction);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0048511(rhythmic process);GO:0005125(cytokine activity);GO:0005615(extracellular space);GO:0009435(NAD biosynthetic process);GO:0019363(pyridine nucleotide biosynthetic process);GO:0004514(nicotinate-nucleotide diphosphorylase (carboxylating) activity);GO:0008144(drug binding);GO:0042803(protein homodimerization activity);GO:0047280(nicotinamide phosphoribosyltransferase activity);GO:0007565(female pregnancy);GO:0007623(circadian rhythm);GO:0014070(response to organic cyclic compound);GO:0032922(circadian regulation of gene expression);GO:0048661(positive regulation of smooth muscle cell proliferation);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0007165(signal transduction);GO:0007267(cell-cell signaling);GO:0051770(positive regulation of nitric-oxide synthase biosynthetic process);GO:0008284(positive regulation of cell proliferation);GO:0034356(NAD biosynthesis via nicotinamide riboside salvage pathway)","00760(Nicotinate and nicotinamide metabolism);04621(NOD-like receptor signaling pathway)","K03462","EC:2.4.2.12","nicotinamide phosphoribosyltransferase [Source:HGNC Symbol;Acc:HGNC:30092]",{"v":7.968692,"d":"7.97"},{"v":59.486519,"d":"59.49"},{"v":0.13395794768223,"d":"0.13"},{"v":-2.90014791653205,"d":"-2.90"},{"v":4.88262191900722e-05,"d":"0.00"},{"v":0.00141709584998163,"d":"0.00"},"down","yes"]
[161445,0,"chr5","-",176905005,177006408,"ENST00000377227",15,2570,"MSTRG.12568","UIMC1","GO:0005634(nucleus);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0016569(covalent chromatin modification);GO:0005515(protein binding);GO:0006281(DNA repair);GO:0006974(cellular response to DNA damage stimulus);GO:0016604(nuclear body);GO:0005654(nucleoplasm);GO:0016579(protein deubiquitination);GO:0042393(histone binding);GO:0031572(G2 DNA damage checkpoint);GO:0045739(positive regulation of DNA repair);GO:0006302(double-strand break repair);GO:0006303(double-strand break repair via nonhomologous end joining);GO:0010212(response to ionizing radiation);GO:0045892(negative regulation of transcription, DNA-templated);GO:0070531(BRCA1-A complex);GO:0070537(histone H2A K63-linked deubiquitination);GO:0070530(K63-linked polyubiquitin binding)","03440(Homologous recombination)","K20775","NA","ubiquitin interaction motif containing 1 [Source:HGNC Symbol;Acc:HGNC:30298]",{"v":0.509604,"d":"0.51"},{"v":3.977036,"d":"3.98"},{"v":0.128136632406647,"d":"0.13"},{"v":-2.96424511463132,"d":"-2.96"},{"v":4.91519194561395e-05,"d":"0.00"},{"v":1.42447826952132E-3,"d":"0.00"},"down","yes"]
[68303,0,"chr16","+",2223566,2235742,"ENST00000301727",14,2573,"ENSG00000167967","E4F1","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0005654(nucleoplasm);GO:0016740(transferase activity);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0016567(protein ubiquitination);GO:0003677(DNA binding);GO:0051301(cell division);GO:0005515(protein binding);GO:0007049(cell cycle);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0040008(regulation of growth);GO:0016032(viral process);GO:0003713(transcription coactivator activity);GO:0003714(transcription corepressor activity);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0008283(cell proliferation);GO:0000977(RNA polymerase II regulatory region sequence-specific DNA binding);GO:0001227(transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding);GO:0071850(mitotic cell cycle arrest);GO:0010564(regulation of cell cycle process);GO:0035497(cAMP response element binding);GO:0006260(DNA replication);GO:0009794(regulation of mitotic cell cycle, embryonic);GO:0005819(spindle)","NA","NA","NA","E4F transcription factor 1 [Source:HGNC Symbol;Acc:HGNC:3121]",{"v":5.043149,"d":"5.04"},{"v":0.708858,"d":"0.71"},{"v":7.11447003490121,"d":"7.11"},{"v":2.8307562927326,"d":"2.83"},{"v":4.94608516912549E-5,"d":"0.00"},{"v":0.00142967673469141,"d":"0.00"},"up","yes"]
[90617,0,"chr18","-",9546910,9551939,"ENST00000582594",4,2982,"MSTRG.7416","PPP4R1","GO:0007165(signal transduction);GO:0004721(phosphoprotein phosphatase activity);GO:0005515(protein binding);GO:0050790(regulation of catalytic activity);GO:0019888(protein phosphatase regulator activity);GO:0006470(protein dephosphorylation);GO:0030289(protein phosphatase 4 complex);GO:0006468(protein phosphorylation)","NA","NA","NA","protein phosphatase 4 regulatory subunit 1 [Source:HGNC Symbol;Acc:HGNC:9320]",{"v":1.957199,"d":"1.96"},{"v":0.262961,"d":"0.26"},{"v":7.44292499648237,"d":"7.44"},{"v":2.8958696977615,"d":"2.90"},{"v":4.94744903681772e-05,"d":"0.00"},{"v":0.00142967673469141,"d":"0.00"},"up","yes"]
[4261,0,"chr1","+",36156202,36180840,"ENST00000373151",17,3324,"MSTRG.418","MAP7D1","GO:0000226(microtubule cytoskeleton organization);GO:0015630(microtubule cytoskeleton);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005856(cytoskeleton);GO:0005819(spindle);GO:0005198(structural molecule activity)","NA","NA","NA","MAP7 domain containing 1 [Source:HGNC Symbol;Acc:HGNC:25514]",{"v":1.092574,"d":"1.09"},{"v":8.278053,"d":"8.28"},{"v":0.131984417108709,"d":"0.13"},{"v":-2.9215604886906,"d":"-2.92"},{"v":4.96634642173547e-05,"d":"0.00"},{"v":0.00143306366111581,"d":"0.00"},"down","yes"]
[196578,0,"chrX","-",41514934,41923012,"ENST00000421587",25,8204,"ENSG00000147044","CASK","GO:0005737(cytoplasm);GO:0001953(negative regulation of cell-matrix adhesion);GO:0005634(nucleus);GO:0016020(membrane);GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0005925(focal adhesion);GO:0005516(calmodulin binding);GO:0005829(cytosol);GO:0046037(GMP metabolic process);GO:0046710(GDP metabolic process);GO:0007155(cell adhesion);GO:0015629(actin cytoskeleton);GO:0005730(nucleolus);GO:0007269(neurotransmitter secretion);GO:0005604(basement membrane);GO:0004385(guanylate kinase activity);GO:0010839(negative regulation of keratinocyte proliferation);GO:0061045(negative regulation of wound healing);GO:0090288(negative regulation of cellular response to growth factor stimulus);GO:0005652(nuclear lamina);GO:0005911(cell-cell junction);GO:0016363(nuclear matrix);GO:0042734(presynaptic membrane);GO:0060170(ciliary membrane);GO:0042043(neurexin family protein binding);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0070509(calcium ion import);GO:0090280(positive regulation of calcium ion import);GO:0016323(basolateral plasma membrane);GO:0031982(vesicle);GO:0045202(synapse)","NA","NA","NA","calcium/calmodulin dependent serine protein kinase [Source:HGNC Symbol;Acc:HGNC:1497]",{"v":0.969322,"d":"0.97"},{"v":0.133937,"d":"0.13"},{"v":7.2371488087683,"d":"7.24"},{"v":2.85542143631205,"d":"2.86"},{"v":4.99958672142462e-05,"d":"0.00"},{"v":1.44057355921222E-3,"d":"0.00"},"up","yes"]
[128096,0,"chr21","+",46561285,46569708,"ENST00000478105",5,3234,"ENSG00000160305","DIP2A","GO:0005634(nucleus);GO:0003824(catalytic activity);GO:0008152(metabolic process);GO:0005515(protein binding);GO:0007275(multicellular organism development);GO:0042981(regulation of apoptotic process);GO:0010629(negative regulation of gene expression);GO:0009986(cell surface)","NA","NA","NA","disco interacting protein 2 homolog A [Source:HGNC Symbol;Acc:HGNC:17217]",{"v":1.801279,"d":"1.80"},{"v":0.244363,"d":"0.24"},{"v":7.3713246277055,"d":"7.37"},{"v":2.88192389504694,"d":"2.88"},{"v":5.02575839315326E-5,"d":"0.00"},{"v":0.00144602800568421,"d":"0.00"},"up","yes"]
[165239,0,"chr6","-",33303573,33314212,"ENST00000426633",7,1888,"MSTRG.12950","TAPBP","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005515(protein binding);GO:0000139(Golgi membrane);GO:0019885(antigen processing and presentation of endogenous peptide antigen via MHC class I);GO:0006890(retrograde vesicle-mediated transport, Golgi to ER);GO:0002479(antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent);GO:0010468(regulation of gene expression);GO:0030670(phagocytic vesicle membrane);GO:0006955(immune response);GO:0006461(protein complex assembly);GO:0051082(unfolded protein binding);GO:0033116(endoplasmic reticulum-Golgi intermediate compartment membrane);GO:0042825(TAP complex);GO:0015433(peptide antigen-transporting ATPase activity);GO:0042288(MHC class I protein binding);GO:0042605(peptide antigen binding);GO:0046978(TAP1 binding);GO:0046979(TAP2 binding);GO:0002474(antigen processing and presentation of peptide antigen via MHC class I);GO:0015833(peptide transport);GO:0042886(amide transport);GO:0050823(peptide antigen stabilization);GO:0061635(regulation of protein complex stability);GO:1990668(vesicle fusion with endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membrane);GO:0042824(MHC class I peptide loading complex);GO:0071556(integral component of lumenal side of endoplasmic reticulum membrane);GO:0002397(MHC class I protein complex assembly)","04612(Antigen processing and presentation)","K08058","NA","TAP binding protein [Source:HGNC Symbol;Acc:HGNC:11566]",{"v":15.649515,"d":"15.65"},{"v":2.254377,"d":"2.25"},{"v":6.94183581539379,"d":"6.94"},{"v":2.79531724371477,"d":"2.80"},{"v":5.13337144236101e-05,"d":"0.00"},{"v":0.00147486562533906,"d":"0.00"},"up","yes"]
[41209,0,"chr12","-",49184959,49188899,"ENST00000295766",4,1887,"MSTRG.3349","TUBA1A","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005525(GTP binding);GO:0000166(nucleotide binding);GO:0003924(GTPase activity);GO:0015630(microtubule cytoskeleton);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0005200(structural constituent of cytoskeleton);GO:0007010(cytoskeleton organization);GO:0005874(microtubule);GO:0007017(microtubule-based process);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0055037(recycling endosome);GO:0000086(G2/M transition of mitotic cell cycle);GO:0010389(regulation of G2/M transition of mitotic cell cycle);GO:0097711(ciliary basal body docking);GO:0036464(cytoplasmic ribonucleoprotein granule);GO:0005198(structural molecule activity);GO:0030705(cytoskeleton-dependent intracellular transport);GO:0051301(cell division);GO:0019904(protein domain specific binding);GO:0005881(cytoplasmic microtubule);GO:0043209(myelin sheath);GO:0045121(membrane raft)","04145(Phagosome);04210(Apoptosis);04530(Tight junction);04540(Gap junction);05130(Pathogenic Escherichia coli infection)","K07374","NA","tubulin alpha 1a [Source:HGNC Symbol;Acc:HGNC:20766]",{"v":15.290627,"d":"15.29"},{"v":2.203794,"d":"2.20"},{"v":6.93831955255346,"d":"6.94"},{"v":2.79458628718925,"d":"2.79"},{"v":5.15077164118536e-05,"d":"0.00"},{"v":1.47773862257456E-3,"d":"0.00"},"up","yes"]
[15472,0,"chr1","-",206904714,206921955,"ENST00000528654",2,572,"MSTRG.1351","FCMR","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005576(extracellular region);GO:0002376(immune system process);GO:0043066(negative regulation of apoptotic process);GO:0006968(cellular defense response)","NA","NA","NA","Fc fragment of IgM receptor [Source:HGNC Symbol;Acc:HGNC:14315]",{"v":12.342882,"d":"12.34"},{"v":1.712897,"d":"1.71"},{"v":7.20585184047844,"d":"7.21"},{"v":2.84916898881654,"d":"2.85"},{"v":5.23417443117791E-5,"d":"0.00"},{"v":1.49871295529027E-3,"d":"0.00"},"up","yes"]
[52940,"j","chr14","+",22766696,22771761,"MSTRG.4177.9",9,1699,"MSTRG.4177","OXA1L","NA","NA","NA","NA","NA",{"v":10.157589,"d":"10.16"},{"v":1.451486,"d":"1.45"},{"v":6.99806198613008,"d":"7.00"},{"v":2.80695544346979,"d":"2.81"},{"v":5.24193513401326E-5,"d":"0.00"},{"v":1.49871295529027E-3,"d":"0.00"},"up","yes"]
[158304,0,"chr5","-",132891817,132963618,"ENST00000378595",13,3348,"MSTRG.12295","AFF4","GO:0005634(nucleus);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0001650(fibrillar center);GO:0005515(protein binding);GO:0005654(nucleoplasm);GO:0006366(transcription from RNA polymerase II promoter);GO:0006368(transcription elongation from RNA polymerase II promoter);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0008023(transcription elongation factor complex);GO:0035327(transcriptionally active chromatin);GO:0007286(spermatid development)","NA","NA","NA","AF4/FMR2 family member 4 [Source:HGNC Symbol;Acc:HGNC:17869]",{"v":0.181351,"d":"0.18"},{"v":1.483138,"d":"1.48"},{"v":0.122275202981786,"d":"0.12"},{"v":-3.03179623527751,"d":"-3.03"},{"v":5.24639601235927E-5,"d":"0.00"},{"v":1.49871295529027E-3,"d":"0.00"},"down","yes"]
[5518,0,"chr1","+",45551067,45570049,"ENST00000351829",9,1166,"MSTRG.521","AKR1A1","GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0005515(protein binding);GO:0005615(extracellular space);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0009055(electron carrier activity);GO:1901687(glutathione derivative biosynthetic process);GO:0004032(alditol:NADP+ 1-oxidoreductase activity);GO:0004033(aldo-keto reductase (NADP) activity);GO:0006081(cellular aldehyde metabolic process);GO:0019640(glucuronate catabolic process to xylulose 5-phosphate);GO:0008106(alcohol dehydrogenase (NADP+) activity);GO:0047939(L-glucuronate reductase activity);GO:0006006(glucose metabolic process);GO:0019853(L-ascorbic acid biosynthetic process);GO:0042840(D-glucuronate catabolic process);GO:0046185(aldehyde catabolic process);GO:0016324(apical plasma membrane)","00010(Glycolysis / Gluconeogenesis);00040(Pentose and glucuronate interconversions);00561(Glycerolipid metabolism)","K00002","EC:1.1.1.2","aldo-keto reductase family 1 member A1 [Source:HGNC Symbol;Acc:HGNC:380]",{"v":0.930195,"d":"0.93"},{"v":7.275,"d":"7.28"},{"v":0.127861855670103,"d":"0.13"},{"v":-2.96734215782386,"d":"-2.97"},{"v":5.25467611703643e-05,"d":"0.00"},{"v":0.00149880362062577,"d":"0.00"},"down","yes"]
[131594,0,"chr22","-",40410290,40636691,"ENST00000402042",14,4343,"MSTRG.10504","MKL1","GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0005737(cytoplasm);GO:0005634(nucleus);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0003713(transcription coactivator activity);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003779(actin binding);GO:0005515(protein binding);GO:0003785(actin monomer binding);GO:0010735(positive regulation of transcription via serum response element binding);GO:0001105(RNA polymerase II transcription coactivator activity);GO:0051145(smooth muscle cell differentiation);GO:0043522(leucine zipper domain binding);GO:0043086(negative regulation of catalytic activity);GO:0004864(protein phosphatase inhibitor activity);GO:0000976(transcription regulatory region sequence-specific DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0001764(neuron migration);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0030036(actin cytoskeleton organization);GO:0030900(forebrain development);GO:0031175(neuron projection development);GO:0043154(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process);GO:0045893(positive regulation of transcription, DNA-templated);GO:2001234(negative regulation of apoptotic signaling pathway)","NA","NA","NA","megakaryoblastic leukemia (translocation) 1 [Source:HGNC Symbol;Acc:HGNC:14334]",{"v":1.915396,"d":"1.92"},{"v":0.267516,"d":"0.27"},{"v":7.1599306209722,"d":"7.16"},{"v":2.83994560798335,"d":"2.84"},{"v":5.26620945134064e-05,"d":"0.00"},{"v":0.00149880362062577,"d":"0.00"},"up","yes"]
[84174,"j","chr17","+",44345166,44353106,"MSTRG.6899.2",13,2537,"MSTRG.6899","GRN","NA","NA","NA","NA","NA",{"v":2.725178,"d":"2.73"},{"v":20.330332,"d":"20.33"},{"v":0.134044933452144,"d":"0.13"},{"v":-2.89921140463517,"d":"-2.90"},{"v":5.26923147876247e-05,"d":"0.00"},{"v":0.00149880362062577,"d":"0.00"},"down","yes"]
[24860,0,"chr11","+",576521,611964,"ENST00000413872",18,5224,"ENSG00000070047","PHRF1","GO:0016020(membrane);GO:0046872(metal ion binding);GO:0070063(RNA polymerase binding);GO:0019904(protein domain specific binding);GO:0006366(transcription from RNA polymerase II promoter);GO:0006397(mRNA processing)","NA","NA","NA","PHD and ring finger domains 1 [Source:HGNC Symbol;Acc:HGNC:24351]",{"v":2.297957,"d":"2.30"},{"v":0.325482,"d":"0.33"},{"v":7.06016615358146,"d":"7.06"},{"v":2.81970213620571,"d":"2.82"},{"v":5.31630217020112E-5,"d":"0.00"},{"v":0.00151004156094703,"d":"0.00"},"up","yes"]
[170233,"j","chr6","-",152121741,152185495,"MSTRG.13391.7",19,4010,"MSTRG.13391","SYNE1","NA","NA","NA","NA","NA",{"v":12.607406,"d":"12.61"},{"v":1.839226,"d":"1.84"},{"v":6.85473454594487,"d":"6.85"},{"v":2.77710079778215,"d":"2.78"},{"v":5.34864873709015e-05,"d":"0.00"},{"v":0.00151707127815648,"d":"0.00"},"up","yes"]
[86703,0,"chr17","-",63695902,63700140,"ENST00000259006",5,3193,"MSTRG.7133","LIMD2","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0005515(protein binding)","NA","NA","NA","LIM domain containing 2 [Source:HGNC Symbol;Acc:HGNC:28142]",{"v":1.856845,"d":"1.86"},{"v":13.814776,"d":"13.81"},{"v":0.134410069334458,"d":"0.13"},{"v":-2.89528687317896,"d":"-2.90"},{"v":5.45805151959316E-5,"d":"0.00"},{"v":1.54553511869439E-3,"d":"0.00"},"down","yes"]
[8688,0,"chr1","+",108692341,108701803,"ENST00000370021",7,3728,"MSTRG.752","PRPF38B","GO:0003723(RNA binding);GO:0006397(mRNA processing);GO:0008380(RNA splicing);GO:0005634(nucleus);GO:0005681(spliceosomal complex);GO:0071011(precatalytic spliceosome)","03040(Spliceosome)","NA","NA","pre-mRNA processing factor 38B [Source:HGNC Symbol;Acc:HGNC:25512]",{"v":2.357489,"d":"2.36"},{"v":0.328555,"d":"0.33"},{"v":7.17532528800353,"d":"7.18"},{"v":2.84304423677117,"d":"2.84"},{"v":5.46642471737527e-05,"d":"0.00"},{"v":1.54553511869439E-3,"d":"0.00"},"up","yes"]
[127896,0,"chr21","+",45074600,45226560,"ENST00000389861",13,5031,"ENSG00000197381","ADARB1","GO:0003723(RNA binding);GO:0006396(RNA processing);GO:0006397(mRNA processing);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0016787(hydrolase activity);GO:0005515(protein binding);GO:0002376(immune system process);GO:0045087(innate immune response);GO:0005730(nucleolus);GO:0051607(defense response to virus);GO:0004000(adenosine deaminase activity);GO:0008285(negative regulation of cell proliferation);GO:0051726(regulation of cell cycle);GO:0030336(negative regulation of cell migration);GO:0045070(positive regulation of viral genome replication);GO:0044387(negative regulation of protein kinase activity by regulation of protein phosphorylation);GO:0003729(mRNA binding);GO:0003726(double-stranded RNA adenosine deaminase activity);GO:0006382(adenosine to inosine editing);GO:0007274(neuromuscular synaptic transmission);GO:0021610(facial nerve morphogenesis);GO:0021618(hypoglossal nerve morphogenesis);GO:0021965(spinal cord ventral commissure morphogenesis);GO:0035264(multicellular organism growth);GO:0050884(neuromuscular process controlling posture);GO:0060384(innervation);GO:0060415(muscle tissue morphogenesis);GO:0061744(motor behavior);GO:0097049(motor neuron apoptotic process)","NA","NA","NA","adenosine deaminase, RNA specific B1 [Source:HGNC Symbol;Acc:HGNC:226]",{"v":1.244402,"d":"1.24"},{"v":0.17135,"d":"0.17"},{"v":7.26234023927633,"d":"7.26"},{"v":2.86043452171318,"d":"2.86"},{"v":5.47222220010483e-05,"d":"0.00"},{"v":1.54553511869439E-3,"d":"0.00"},"up","yes"]
[2416,0,"chr1","-",20807004,21176847,"ENST00000400422",35,5762,"ENSG00000075151","EIF4G3","GO:0003723(RNA binding);GO:0003743(translation initiation factor activity);GO:0006412(translation);GO:0006413(translational initiation);GO:0005829(cytosol);GO:0006417(regulation of translation);GO:0016032(viral process);GO:0008135(translation factor activity, RNA binding);GO:0000339(RNA cap binding);GO:0006446(regulation of translational initiation);GO:0016281(eukaryotic translation initiation factor 4F complex)","03013(RNA transport);05416(Viral myocarditis)","K03260","NA","eukaryotic translation initiation factor 4 gamma 3 [Source:HGNC Symbol;Acc:HGNC:3298]",{"v":0.48536,"d":"0.49"},{"v":3.638601,"d":"3.64"},{"v":0.133391927281942,"d":"0.13"},{"v":-2.90625673588149,"d":"-2.91"},{"v":5.49978347892315e-05,"d":"0.00"},{"v":0.00154915859209362,"d":"0.00"},"down","yes"]
[149996,"j","chr4","-",108047778,108167003,"MSTRG.11788.6",11,2658,"MSTRG.11788","LEF1","NA","NA","NA","NA","NA",{"v":5.315759,"d":"5.32"},{"v":0.762208,"d":"0.76"},{"v":6.97415797262689,"d":"6.97"},{"v":2.80201904317172,"d":"2.80"},{"v":5.50056811796061e-05,"d":"0.00"},{"v":0.00154915859209362,"d":"0.00"},"up","yes"]
[56904,0,"chr14","-",75013764,75051532,"ENST00000355774",13,7896,"MSTRG.4546","MLH3","GO:0005634(nucleus);GO:0005524(ATP binding);GO:0006281(DNA repair);GO:0006974(cellular response to DNA damage stimulus);GO:0030983(mismatched DNA binding);GO:0006298(mismatch repair);GO:0005515(protein binding);GO:0007131(reciprocal meiotic recombination);GO:0016887(ATPase activity);GO:0000795(synaptonemal complex);GO:0032300(mismatch repair complex);GO:0003697(single-stranded DNA binding);GO:0003696(satellite DNA binding);GO:0005712(chiasma);GO:0003682(chromatin binding);GO:0019237(centromeric DNA binding);GO:0007130(synaptonemal complex assembly);GO:0007140(male meiotic nuclear division);GO:0007144(female meiosis I);GO:0008104(protein localization);GO:0000793(condensed chromosome);GO:0000794(condensed nuclear chromosome);GO:0001673(male germ cell nucleus)","03430(Mismatch repair)","K08739","NA","mutL homolog 3 [Source:HGNC Symbol;Acc:HGNC:7128]",{"v":1.035861,"d":"1.04"},{"v":0.144914,"d":"0.14"},{"v":7.14810853333701,"d":"7.15"},{"v":2.83756153971213,"d":"2.84"},{"v":5.56246795430368e-05,"d":"0.00"},{"v":0.0015643853536836,"d":"0.00"},"up","yes"]
[5513,0,"chr1","+",45550783,45570048,"ENST00000621846",10,1360,"MSTRG.521","AKR1A1","GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0005515(protein binding);GO:0005615(extracellular space);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0009055(electron carrier activity);GO:1901687(glutathione derivative biosynthetic process);GO:0004032(alditol:NADP+ 1-oxidoreductase activity);GO:0004033(aldo-keto reductase (NADP) activity);GO:0006081(cellular aldehyde metabolic process);GO:0019640(glucuronate catabolic process to xylulose 5-phosphate);GO:0008106(alcohol dehydrogenase (NADP+) activity);GO:0047939(L-glucuronate reductase activity);GO:0006006(glucose metabolic process);GO:0019853(L-ascorbic acid biosynthetic process);GO:0042840(D-glucuronate catabolic process);GO:0046185(aldehyde catabolic process);GO:0016324(apical plasma membrane)","00010(Glycolysis / Gluconeogenesis);00040(Pentose and glucuronate interconversions);00561(Glycerolipid metabolism)","K00002","EC:1.1.1.2","aldo-keto reductase family 1 member A1 [Source:HGNC Symbol;Acc:HGNC:380]",{"v":4.346333,"d":"4.35"},{"v":0.598677,"d":"0.60"},{"v":7.25989640490615,"d":"7.26"},{"v":2.8599489618306,"d":"2.86"},{"v":5.62094041801428e-05,"d":"0.00"},{"v":0.00157756020131685,"d":"0.00"},"up","yes"]
[186461,0,"chr8","-",108233394,108248698,"ENST00000521440",6,746,"MSTRG.14515","EIF3E","GO:0005737(cytoplasm);GO:0003743(translation initiation factor activity);GO:0005852(eukaryotic translation initiation factor 3 complex);GO:0005829(cytosol);GO:0016604(nuclear body);GO:0006413(translational initiation);GO:0006412(translation);GO:0005634(nucleus);GO:0001731(formation of translation preinitiation complex);GO:0006446(regulation of translational initiation);GO:0016282(eukaryotic 43S preinitiation complex);GO:0033290(eukaryotic 48S preinitiation complex);GO:0003723(RNA binding);GO:0016020(membrane);GO:0005515(protein binding);GO:0005654(nucleoplasm);GO:0045296(cadherin binding);GO:0070062(extracellular exosome);GO:0047485(protein N-terminus binding);GO:0000785(chromatin);GO:0016605(PML body);GO:0000184(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay);GO:0045727(positive regulation of translation);GO:1902416(positive regulation of mRNA binding);GO:0045947(negative regulation of translational initiation)","03013(RNA transport);05160(Hepatitis C)","NA","NA","eukaryotic translation initiation factor 3 subunit E [Source:HGNC Symbol;Acc:HGNC:3277]",{"v":10.952918,"d":"10.95"},{"v":1.535556,"d":"1.54"},{"v":7.13286783419165,"d":"7.13"},{"v":2.83448224193049,"d":"2.83"},{"v":5.62511449988782E-5,"d":"0.00"},{"v":0.00157756020131685,"d":"0.00"},"up","yes"]
[22606,0,"chr10","-",97356701,97373593,"ENST00000479481",17,3271,"MSTRG.1890","RRP12","GO:0003723(RNA binding);GO:0005634(nucleus);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005730(nucleolus);GO:0031965(nuclear membrane)","NA","NA","NA","ribosomal RNA processing 12 homolog [Source:HGNC Symbol;Acc:HGNC:29100]",{"v":0.802319,"d":"0.80"},{"v":6.019194,"d":"6.02"},{"v":0.133293427658255,"d":"0.13"},{"v":-2.90732244813341,"d":"-2.91"},{"v":5.64091581360831e-05,"d":"0.00"},{"v":0.00157977288872554,"d":"0.00"},"down","yes"]
[30349,"j","chr11","+",62787403,62790118,"MSTRG.2478.1",5,657,"MSTRG.2478","TMEM179B","NA","NA","NA","NA","NA",{"v":22.065384,"d":"22.07"},{"v":3.163173,"d":"3.16"},{"v":6.97571204610055,"d":"6.98"},{"v":2.80234048761527,"d":"2.80"},{"v":5.65123289714062e-05,"d":"0.00"},{"v":1.5804456371163E-3,"d":"0.00"},"up","yes"]
[80044,0,"chr17","-",17246837,17281191,"ENST00000578317",12,1625,"MSTRG.6490","COPS3","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0005515(protein binding);GO:0008180(COP9 signalosome);GO:0043687(post-translational protein modification);GO:0007165(signal transduction);GO:0000338(protein deneddylation);GO:0006283(transcription-coupled nucleotide-excision repair);GO:0006511(ubiquitin-dependent protein catabolic process);GO:0000715(nucleotide-excision repair, DNA damage recognition);GO:0009416(response to light stimulus);GO:0001701(in utero embryonic development)","NA","NA","NA","COP9 signalosome subunit 3 [Source:HGNC Symbol;Acc:HGNC:2239]",{"v":6.595592,"d":"6.60"},{"v":0.946731,"d":"0.95"},{"v":6.96670120657293,"d":"6.97"},{"v":2.80047568916537,"d":"2.80"},{"v":5.72852821200674e-05,"d":"0.00"},{"v":0.00159982169702588,"d":"0.00"},"up","yes"]
[198225,"j","chrX","-",72255661,72277300,"MSTRG.15362.1",8,1322,"MSTRG.15362","RPS4X","NA","NA","NA","NA","NA",{"v":201.368576,"d":"201.37"},{"v":29.841511,"d":"29.84"},{"v":6.74793498224671,"d":"6.75"},{"v":2.75444607302647,"d":"2.75"},{"v":5.74385826146226e-05,"d":"0.00"},{"v":0.00160186259448154,"d":"0.00"},"up","yes"]
[87712,0,"chr17","+",74737232,74747335,"ENST00000392610",8,2858,"MSTRG.7180","RAB37","GO:0005525(GTP binding);GO:0003924(GTPase activity);GO:0006810(transport);GO:0015031(protein transport);GO:0000166(nucleotide binding);GO:0005515(protein binding);GO:0031410(cytoplasmic vesicle);GO:0005886(plasma membrane);GO:0005768(endosome);GO:0009306(protein secretion);GO:0043312(neutrophil degranulation);GO:0035579(specific granule membrane);GO:0035577(azurophil granule membrane);GO:0005793(endoplasmic reticulum-Golgi intermediate compartment);GO:0008021(synaptic vesicle);GO:0072659(protein localization to plasma membrane);GO:0030667(secretory granule membrane);GO:0006904(vesicle docking involved in exocytosis);GO:0017157(regulation of exocytosis)","NA","NA","NA","RAB37, member RAS oncogene family [Source:HGNC Symbol;Acc:HGNC:30268]",{"v":2.990927,"d":"2.99"},{"v":0.419742,"d":"0.42"},{"v":7.12563193580819,"d":"7.13"},{"v":2.83301796507405,"d":"2.83"},{"v":5.75796808570296e-05,"d":"0.00"},{"v":1.60355797399326E-3,"d":"0.00"},"up","yes"]
[41130,"j","chr12","-",49002281,49060107,"MSTRG.3345.4",66,21796,"MSTRG.3345","KMT2D","NA","NA","NA","NA","NA",{"v":0.634301,"d":"0.63"},{"v":4.642551,"d":"4.64"},{"v":0.136627685942492,"d":"0.14"},{"v":-2.8716782369933,"d":"-2.87"},{"v":5.77124108804263E-5,"d":"0.00"},{"v":1.60501590593364E-3,"d":"0.00"},"down","yes"]
[175924,0,"chr7","+",90346676,90391455,"ENST00000222511",10,7531,"ENSG00000105793","GTPBP10","GO:0005525(GTP binding);GO:0003723(RNA binding);GO:0005634(nucleus);GO:0000166(nucleotide binding);GO:0005694(chromosome);GO:0005515(protein binding);GO:0042254(ribosome biogenesis);GO:0005730(nucleolus);GO:0005739(mitochondrion)","NA","NA","NA","GTP binding protein 10 [Source:HGNC Symbol;Acc:HGNC:25106]",{"v":0.092692,"d":"0.09"},{"v":0.742188,"d":"0.74"},{"v":0.124890189547662,"d":"0.12"},{"v":-3.00126794097448,"d":"-3.00"},{"v":5.78933539723009e-05,"d":"0.00"},{"v":1.60780875120849E-3,"d":"0.00"},"down","yes"]
[156901,"j","chr5","+",96662352,96774694,"MSTRG.12236.6",31,4459,"MSTRG.12236","CAST","NA","NA","NA","NA","NA",{"v":1.840883,"d":"1.84"},{"v":0.258458,"d":"0.26"},{"v":7.12256149935386,"d":"7.12"},{"v":2.83239617347153,"d":"2.83"},{"v":5.81819479441253E-5,"d":"0.00"},{"v":1.61357935631707E-3,"d":"0.00"},"up","yes"]
[4044,"j","chr1","+",33256545,33299353,"MSTRG.385.1",8,1642,"MSTRG.385","ZNF362","NA","NA","NA","NA","NA",{"v":1.201831,"d":"1.20"},{"v":9.030509,"d":"9.03"},{"v":0.133085632271669,"d":"0.13"},{"v":-2.90957326645699,"d":"-2.91"},{"v":5.8705275857776e-05,"d":"0.00"},{"v":0.00162222362327037,"d":"0.00"},"down","yes"]
[41371,0,"chr12","-",49791146,49828425,"ENST00000335999",13,4900,"ENSG00000167566","NCKAP5L","GO:0005737(cytoplasm);GO:0005856(cytoskeleton);GO:0005874(microtubule);GO:0005813(centrosome);GO:0005815(microtubule organizing center);GO:0005515(protein binding);GO:0001578(microtubule bundle formation);GO:0035371(microtubule plus-end);GO:0007019(microtubule depolymerization)","NA","NA","NA","NCK associated protein 5 like [Source:HGNC Symbol;Acc:HGNC:29321]",{"v":2.655775,"d":"2.66"},{"v":0.383692,"d":"0.38"},{"v":6.92163245519844,"d":"6.92"},{"v":2.79111233515537,"d":"2.79"},{"v":5.87264032928857E-5,"d":"0.00"},{"v":0.00162222362327037,"d":"0.00"},"up","yes"]
[149716,0,"chr4","-",102795976,102828159,"ENST00000394803",8,2227,"MSTRG.11774","UBE2D3","GO:0016020(membrane);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0016740(transferase activity);GO:0016567(protein ubiquitination);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0006281(DNA repair);GO:0006974(cellular response to DNA damage stimulus);GO:0006915(apoptotic process);GO:0005768(endosome);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0061631(ubiquitin conjugating enzyme activity);GO:0061418(regulation of transcription from RNA polymerase II promoter in response to hypoxia);GO:0010008(endosome membrane);GO:0035666(TRIF-dependent toll-like receptor signaling pathway);GO:0004842(ubiquitin-protein transferase activity);GO:0030509(BMP signaling pathway);GO:0006464(cellular protein modification process);GO:0043161(proteasome-mediated ubiquitin-dependent protein catabolic process);GO:0070936(protein K48-linked ubiquitination);GO:0070979(protein K11-linked ubiquitination);GO:1903955(positive regulation of protein targeting to mitochondrion);GO:0006511(ubiquitin-dependent protein catabolic process);GO:0000209(protein polyubiquitination);GO:0006513(protein monoubiquitination);GO:0051865(protein autoubiquitination);GO:0000122(negative regulation of transcription from RNA polymerase II promoter)","04141(Protein processing in endoplasmic reticulum);04120(Ubiquitin mediated proteolysis)","K06689","EC:2.3.2.23","ubiquitin conjugating enzyme E2 D3 [Source:HGNC Symbol;Acc:HGNC:12476]",{"v":1.939162,"d":"1.94"},{"v":14.344512,"d":"14.34"},{"v":0.135184940414843,"d":"0.14"},{"v":-2.88699365036,"d":"-2.89"},{"v":5.87373637632452e-05,"d":"0.00"},{"v":0.00162222362327037,"d":"0.00"},"down","yes"]
[71543,"j","chr16","+",29806088,29811164,"MSTRG.5813.1",7,2580,"MSTRG.5813","MAZ","NA","NA","NA","NA","NA",{"v":0.963,"d":"0.96"},{"v":7.184508,"d":"7.18"},{"v":0.134038405970179,"d":"0.13"},{"v":-2.89928166014514,"d":"-2.90"},{"v":5.89590712676228e-05,"d":"0.00"},{"v":0.00162609770037554,"d":"0.00"},"down","yes"]
[28523,0,"chr11","+",46347588,46380367,"ENST00000318201",30,3213,"MSTRG.2358","DGKZ","GO:0005737(cytoplasm);GO:0005634(nucleus);GO:0016607(nuclear speck);GO:0016020(membrane);GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0035556(intracellular signal transduction);GO:0008152(metabolic process);GO:0003951(NAD+ kinase activity);GO:0005886(plasma membrane);GO:0004143(diacylglycerol kinase activity);GO:0007205(protein kinase C-activating G-protein coupled receptor signaling pathway);GO:0005515(protein binding);GO:0030027(lamellipodium);GO:0030168(platelet activation);GO:0016477(cell migration);GO:0046339(diacylglycerol metabolic process);GO:0046834(lipid phosphorylation);GO:0046486(glycerolipid metabolic process);GO:0005622(intracellular)","00561(Glycerolipid metabolism);00564(Glycerophospholipid metabolism);04070(Phosphatidylinositol signaling system);04072(Phospholipase D signaling pathway);05231(Choline metabolism in cancer)","K00901","EC:2.7.1.107","diacylglycerol kinase zeta [Source:HGNC Symbol;Acc:HGNC:2857]",{"v":5.275519,"d":"5.28"},{"v":0.769773,"d":"0.77"},{"v":6.85334377797091,"d":"6.85"},{"v":2.77680805739674,"d":"2.78"},{"v":5.99467985723088e-05,"d":"0.00"},{"v":0.0016510588605405,"d":"0.00"},"up","yes"]
[171271,0,"chr7","+",1530714,1543043,"ENST00000343242",3,3368,"MSTRG.13443","MAFK","GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0005515(protein binding);GO:0000976(transcription regulatory region sequence-specific DNA binding);GO:0001221(transcription cofactor binding);GO:0071535(RING-like zinc finger domain binding);GO:0007399(nervous system development);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0043565(sequence-specific DNA binding);GO:0001227(transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding);GO:0007596(blood coagulation)","NA","NA","NA","MAF bZIP transcription factor K [Source:HGNC Symbol;Acc:HGNC:6782]",{"v":5.768564,"d":"5.77"},{"v":0.842925,"d":"0.84"},{"v":6.84350802265919,"d":"6.84"},{"v":2.77473604872536,"d":"2.77"},{"v":6.03196799497668e-05,"d":"0.00"},{"v":0.00165904045349441,"d":"0.00"},"up","yes"]
[130440,0,"chr22","-",31281613,31292534,"ENST00000441972",5,2374,"MSTRG.10386","PIK3IP1","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0014067(negative regulation of phosphatidylinositol 3-kinase signaling);GO:0043553(negative regulation of phosphatidylinositol 3-kinase activity);GO:0070062(extracellular exosome);GO:0036313(phosphatidylinositol 3-kinase catalytic subunit binding)","NA","NA","NA","phosphoinositide-3-kinase interacting protein 1 [Source:HGNC Symbol;Acc:HGNC:24942]",{"v":0.342637,"d":"0.34"},{"v":2.705949,"d":"2.71"},{"v":0.126623598597017,"d":"0.13"},{"v":-2.98138179275786,"d":"-2.98"},{"v":6.06349364083515e-05,"d":"0.00"},{"v":0.00166541734553227,"d":"0.00"},"down","yes"]
[98501,0,"chr19","+",18153158,18178117,"ENST00000593731",25,5142,"MSTRG.7986","AC007192.1","NA","NA","NA","NA","NA",{"v":11.291834,"d":"11.29"},{"v":1.674969,"d":"1.67"},{"v":6.74151820123238,"d":"6.74"},{"v":2.75307352534493,"d":"2.75"},{"v":6.09392899647089e-05,"d":"0.00"},{"v":1.67147766760344E-3,"d":"0.00"},"up","yes"]
[7463,0,"chr1","-",77948405,77979092,"ENST00000370767",20,2524,"MSTRG.660","FUBP1","GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0005634(nucleus);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0010628(positive regulation of gene expression);GO:0006366(transcription from RNA polymerase II promoter);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0003697(single-stranded DNA binding)","NA","NA","NA","far upstream element binding protein 1 [Source:HGNC Symbol;Acc:HGNC:4004]",{"v":5.127325,"d":"5.13"},{"v":0.744964,"d":"0.74"},{"v":6.88264802057549,"d":"6.88"},{"v":2.78296373224603,"d":"2.78"},{"v":6.12636497229381e-05,"d":"0.00"},{"v":0.00167806935208179,"d":"0.00"},"up","yes"]
[139452,0,"chr3","+",119468938,119494708,"ENST00000295588",11,3533,"ENSG00000163389","POGLUT1","GO:0016740(transferase activity);GO:0016757(transferase activity, transferring glycosyl groups);GO:0005783(endoplasmic reticulum);GO:0007275(multicellular organism development);GO:0006486(protein glycosylation);GO:0005788(endoplasmic reticulum lumen);GO:0070062(extracellular exosome);GO:0035252(UDP-xylosyltransferase activity);GO:0045747(positive regulation of Notch signaling pathway);GO:0010470(regulation of gastrulation);GO:0007369(gastrulation);GO:0006664(glycolipid metabolic process);GO:0030158(protein xylosyltransferase activity);GO:0035251(UDP-glucosyltransferase activity);GO:0046527(glucosyltransferase activity);GO:0001756(somitogenesis);GO:0006493(protein O-linked glycosylation);GO:0008593(regulation of Notch signaling pathway);GO:0018242(protein O-linked glycosylation via serine);GO:0048318(axial mesoderm development);GO:0048339(paraxial mesoderm development);GO:0060537(muscle tissue development);GO:0072358(cardiovascular system development)","00514(Other types of O-glycan biosynthesis)","K13667","EC:2.4.1.-","protein O-glucosyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:22954]",{"v":0.230407,"d":"0.23"},{"v":1.815841,"d":"1.82"},{"v":0.126887210939724,"d":"0.13"},{"v":-2.97838142873149,"d":"-2.98"},{"v":6.15353622433941e-05,"d":"0.00"},{"v":0.00168320289489876,"d":"0.00"},"down","yes"]
[101787,"j","chr19","+",41264417,41306991,"MSTRG.8172.10",15,2822,"MSTRG.8172","HNRNPUL1","NA","NA","NA","NA","NA",{"v":36.585335,"d":"36.59"},{"v":5.464828,"d":"5.46"},{"v":6.69469103144692,"d":"6.69"},{"v":2.74301747486474,"d":"2.74"},{"v":6.20677734554247e-05,"d":"0.00"},{"v":1.6939447782499E-3,"d":"0.00"},"up","yes"]
[76718,0,"chr16","-",88645965,88650988,"ENST00000563526",4,1052,"MSTRG.6226","CYBA","GO:0016020(membrane);GO:0046872(metal ion binding);GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0020037(heme binding);GO:0005789(endoplasmic reticulum membrane);GO:0002479(antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent);GO:0043312(neutrophil degranulation);GO:0035579(specific granule membrane);GO:0070821(tertiary granule membrane);GO:0046982(protein heterodimerization activity);GO:0030670(phagocytic vesicle membrane);GO:0045087(innate immune response);GO:0050766(positive regulation of phagocytosis);GO:0048010(vascular endothelial growth factor receptor signaling pathway);GO:0006954(inflammatory response);GO:0009055(electron carrier activity);GO:0034599(cellular response to oxidative stress);GO:0017124(SH3 domain binding);GO:0032760(positive regulation of tumor necrosis factor production);GO:0006801(superoxide metabolic process);GO:0016175(superoxide-generating NADPH oxidase activity);GO:0042554(superoxide anion generation);GO:0045454(cell redox homeostasis);GO:0045730(respiratory burst);GO:0043020(NADPH oxidase complex);GO:0030141(secretory granule);GO:0001666(response to hypoxia);GO:0001938(positive regulation of endothelial cell proliferation);GO:0003106(negative regulation of glomerular filtration by angiotensin);GO:0008217(regulation of blood pressure);GO:0014823(response to activity);GO:0014895(smooth muscle hypertrophy);GO:0017004(cytochrome complex assembly);GO:0030307(positive regulation of cell growth);GO:0031667(response to nutrient levels);GO:0032755(positive regulation of interleukin-6 production);GO:0032930(positive regulation of superoxide anion generation);GO:0033864(positive regulation of NAD(P)H oxidase activity);GO:0034137(positive regulation of toll-like receptor 2 signaling pathway);GO:0042493(response to drug);GO:0048661(positive regulation of smooth muscle cell proliferation);GO:0050665(hydrogen peroxide biosynthetic process);GO:0051279(regulation of release of sequestered calcium ion into cytosol);GO:0070257(positive regulation of mucus secretion);GO:0070555(response to interleukin-1);GO:0071230(cellular response to amino acid stimulus);GO:0071260(cellular response to mechanical stimulus);GO:0071310(cellular response to organic substance);GO:0071333(cellular response to glucose stimulus);GO:0071356(cellular response to tumor necrosis factor);GO:0071407(cellular response to organic cyclic compound);GO:0071480(cellular response to gamma radiation);GO:0072593(reactive oxygen species metabolic process);GO:1900426(positive regulation of defense response to bacterium);GO:1903428(positive regulation of reactive oxygen species biosynthetic process);GO:1904044(response to aldosterone);GO:1904385(cellular response to angiotensin);GO:1904845(cellular response to L-glutamine);GO:0001725(stress fiber);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005739(mitochondrion);GO:0005768(endosome);GO:0005794(Golgi apparatus);GO:0005925(focal adhesion);GO:0016324(apical plasma membrane);GO:0030425(dendrite);GO:0043025(neuronal cell body);GO:0097038(perinuclear endoplasmic reticulum);GO:0016021(integral component of membrane)","04145(Phagosome);04621(NOD-like receptor signaling pathway);04670(Leukocyte transendothelial migration);04380(Osteoclast differentiation);05418(Fluid shear stress and atherosclerosis);05140(Leishmaniasis)","NA","NA","cytochrome b-245 alpha chain [Source:HGNC Symbol;Acc:HGNC:2577]",{"v":10.953296,"d":"10.95"},{"v":1.576443,"d":"1.58"},{"v":6.94810786054428,"d":"6.95"},{"v":2.79662015022915,"d":"2.80"},{"v":6.20977352603629e-05,"d":"0.00"},{"v":1.6939447782499E-3,"d":"0.00"},"up","yes"]
[183964,0,"chr8","-",56073075,56074506,"ENST00000519606",3,424,"MSTRG.14365","RPS20","GO:0003723(RNA binding);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0006412(translation);GO:0030529(intracellular ribonucleoprotein complex);GO:0005622(intracellular);GO:0003735(structural constituent of ribosome);GO:0005840(ribosome);GO:0015935(small ribosomal subunit);GO:0005515(protein binding);GO:0022627(cytosolic small ribosomal subunit);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0031012(extracellular matrix);GO:0002181(cytoplasmic translation);GO:0006413(translational initiation);GO:0006364(rRNA processing);GO:0000184(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay);GO:0019083(viral transcription);GO:0006614(SRP-dependent cotranslational protein targeting to membrane)","03010(Ribosome)","NA","NA","ribosomal protein S20 [Source:HGNC Symbol;Acc:HGNC:10405]",{"v":26.364452,"d":"26.36"},{"v":3.795057,"d":"3.80"},{"v":6.94705033415835,"d":"6.95"},{"v":2.7964005502715,"d":"2.80"},{"v":6.2716340242807e-05,"d":"0.00"},{"v":0.00170695858532155,"d":"0.00"},"up","yes"]
[145362,0,"chr4","+",2468937,2515855,"ENST00000314289",8,3088,"MSTRG.11497","RNF4","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0016740(transferase activity);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0016567(protein ubiquitination);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0003713(transcription coactivator activity);GO:0045893(positive regulation of transcription, DNA-templated);GO:0005654(nucleoplasm);GO:0042802(identical protein binding);GO:0061630(ubiquitin protein ligase activity);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0004842(ubiquitin-protein transferase activity);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0043161(proteasome-mediated ubiquitin-dependent protein catabolic process);GO:0070534(protein K63-linked ubiquitination);GO:0016605(PML body);GO:0070936(protein K48-linked ubiquitination);GO:0070979(protein K11-linked ubiquitination);GO:0030521(androgen receptor signaling pathway);GO:0008270(zinc ion binding);GO:0050681(androgen receptor binding);GO:0051865(protein autoubiquitination);GO:0085020(protein K6-linked ubiquitination);GO:0031491(nucleosome binding);GO:0032184(SUMO polymer binding);GO:0046685(response to arsenic-containing substance);GO:0090169(regulation of spindle assembly);GO:0090234(regulation of kinetochore assembly);GO:0008134(transcription factor binding)","NA","NA","NA","ring finger protein 4 [Source:HGNC Symbol;Acc:HGNC:10067]",{"v":3.471328,"d":"3.47"},{"v":25.179121,"d":"25.18"},{"v":0.137865336919426,"d":"0.14"},{"v":-2.85866832505964,"d":"-2.86"},{"v":6.27457733186108e-05,"d":"0.00"},{"v":0.00170695858532155,"d":"0.00"},"down","yes"]
[16972,0,"chr1","-",231332753,231337852,"ENST00000366645",1,5100,"MSTRG.1462","EXOC8","GO:0006810(transport);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0015031(protein transport);GO:0005829(cytosol);GO:0006887(exocytosis);GO:0000145(exocyst);GO:0042995(cell projection);GO:0005515(protein binding);GO:0048471(perinuclear region of cytoplasm);GO:0005886(plasma membrane);GO:0030426(growth cone);GO:0022617(extracellular matrix disassembly);GO:0005770(late endosome);GO:0017160(Ral GTPase binding);GO:0016241(regulation of macroautophagy);GO:0051601(exocyst localization);GO:0007032(endosome organization);GO:0001927(exocyst assembly);GO:0034613(cellular protein localization)","NA","NA","NA","exocyst complex component 8 [Source:HGNC Symbol;Acc:HGNC:24659]",{"v":2.76689,"d":"2.77"},{"v":0.404375,"d":"0.40"},{"v":6.84238639876352,"d":"6.84"},{"v":2.77449957733579,"d":"2.77"},{"v":6.34272709158018e-05,"d":"0.00"},{"v":0.00172315067434929,"d":"0.00"},"up","yes"]
[46840,0,"chr12","-",112160190,112382439,"ENST00000377560",76,15759,"ENSG00000173064","HECTD4","GO:0016740(transferase activity);GO:0016567(protein ubiquitination);GO:0004842(ubiquitin-protein transferase activity)","NA","NA","NA","HECT domain E3 ubiquitin protein ligase 4 [Source:HGNC Symbol;Acc:HGNC:26611]",{"v":0.283436,"d":"0.28"},{"v":2.071795,"d":"2.07"},{"v":0.136806971732242,"d":"0.14"},{"v":-2.86978634253456,"d":"-2.87"},{"v":6.35231964000221e-05,"d":"0.00"},{"v":0.00172341193711364,"d":"0.00"},"down","yes"]
[15076,0,"chr1","+",203795714,203854999,"ENST00000550078",17,12481,"MSTRG.1324","ZBED6","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0046983(protein dimerization activity);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0005730(nucleolus);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0000977(RNA polymerase II regulatory region sequence-specific DNA binding);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0045892(negative regulation of transcription, DNA-templated)","NA","NA","NA","zinc finger BED-type containing 6 [Source:HGNC Symbol;Acc:HGNC:33273]",{"v":1.841353,"d":"1.84"},{"v":0.2722,"d":"0.27"},{"v":6.76470609845702,"d":"6.76"},{"v":2.75802725578211,"d":"2.76"},{"v":6.36948561999003e-05,"d":"0.00"},{"v":0.00172430540676229,"d":"0.00"},"up","yes"]
[88666,0,"chr17","+",77453993,77499040,"ENST00000592951",10,1793,"MSTRG.7267","SEPT9","GO:0005737(cytoplasm);GO:0005525(GTP binding);GO:0000166(nucleotide binding);GO:0051301(cell division);GO:0015629(actin cytoskeleton);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0007049(cell cycle);GO:0048471(perinuclear region of cytoplasm);GO:0005874(microtubule);GO:0045296(cadherin binding);GO:0051291(protein heterooligomerization);GO:0001725(stress fiber);GO:0003924(GTPase activity);GO:0005930(axoneme);GO:0031105(septin complex);GO:0097730(non-motile cilium);GO:1902857(positive regulation of non-motile cilium assembly)","05100(Bacterial invasion of epithelial cells)","K16938","NA","septin 9 [Source:HGNC Symbol;Acc:HGNC:7323]",{"v":46.725288,"d":"46.73"},{"v":6.999502,"d":"7.00"},{"v":6.67551605814242,"d":"6.68"},{"v":2.73887937024504,"d":"2.74"},{"v":6.37288356465631e-05,"d":"0.00"},{"v":0.00172430540676229,"d":"0.00"},"up","yes"]
[165241,0,"chr6","-",33304268,33314041,"ENST00000437116",5,1239,"MSTRG.12950","TAPBP","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005515(protein binding);GO:0000139(Golgi membrane);GO:0019885(antigen processing and presentation of endogenous peptide antigen via MHC class I);GO:0006890(retrograde vesicle-mediated transport, Golgi to ER);GO:0002479(antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent);GO:0010468(regulation of gene expression);GO:0030670(phagocytic vesicle membrane);GO:0006955(immune response);GO:0006461(protein complex assembly);GO:0051082(unfolded protein binding);GO:0033116(endoplasmic reticulum-Golgi intermediate compartment membrane);GO:0042825(TAP complex);GO:0015433(peptide antigen-transporting ATPase activity);GO:0042288(MHC class I protein binding);GO:0042605(peptide antigen binding);GO:0046978(TAP1 binding);GO:0046979(TAP2 binding);GO:0002474(antigen processing and presentation of peptide antigen via MHC class I);GO:0015833(peptide transport);GO:0042886(amide transport);GO:0050823(peptide antigen stabilization);GO:0061635(regulation of protein complex stability);GO:1990668(vesicle fusion with endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membrane);GO:0042824(MHC class I peptide loading complex);GO:0071556(integral component of lumenal side of endoplasmic reticulum membrane);GO:0002397(MHC class I protein complex assembly)","04612(Antigen processing and presentation)","NA","NA","TAP binding protein [Source:HGNC Symbol;Acc:HGNC:11566]",{"v":2.909359,"d":"2.91"},{"v":21.354975,"d":"21.35"},{"v":0.136237996064149,"d":"0.14"},{"v":-2.87579897532181,"d":"-2.88"},{"v":6.40789746672615e-05,"d":"0.00"},{"v":0.00173143297179415,"d":"0.00"},"down","yes"]
[146267,0,"chr4","+",17614631,17634105,"ENST00000237380",4,10868,"MSTRG.11543","MED28","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005654(nucleoplasm);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003779(actin binding);GO:0005515(protein binding);GO:0016592(mediator complex);GO:0019827(stem cell population maintenance);GO:0051151(negative regulation of smooth muscle cell differentiation);GO:0005856(cytoskeleton);GO:0030864(cortical actin cytoskeleton)","NA","NA","NA","mediator complex subunit 28 [Source:HGNC Symbol;Acc:HGNC:24628]",{"v":3.713954,"d":"3.71"},{"v":0.553243,"d":"0.55"},{"v":6.71306098766726,"d":"6.71"},{"v":2.74697074925194,"d":"2.75"},{"v":6.42046021906199e-05,"d":"0.00"},{"v":1.73248310343554E-3,"d":"0.00"},"up","yes"]
[184495,0,"chr8","-",67197649,67343677,"ENST00000262215",39,7225,"MSTRG.14401","ARFGEF1","GO:0043547(positive regulation of GTPase activity);GO:0005086(ARF guanyl-nucleotide exchange factor activity);GO:0032012(regulation of ARF protein signal transduction);GO:0006810(transport);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0015031(protein transport);GO:0005794(Golgi apparatus);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0005515(protein binding);GO:0000139(Golgi membrane);GO:0048471(perinuclear region of cytoplasm);GO:0031175(neuron projection development);GO:0051897(positive regulation of protein kinase B signaling);GO:0005802(trans-Golgi network);GO:0005730(nucleolus);GO:0005085(guanyl-nucleotide exchange factor activity);GO:2000114(regulation of establishment of cell polarity);GO:0016363(nuclear matrix);GO:0006887(exocytosis);GO:0007030(Golgi organization);GO:0034237(protein kinase A regulatory subunit binding);GO:0017022(myosin binding);GO:0030837(negative regulation of actin filament polymerization);GO:0090303(positive regulation of wound healing);GO:0034260(negative regulation of GTPase activity);GO:0030532(small nuclear ribonucleoprotein complex);GO:0010256(endomembrane system organization);GO:0090284(positive regulation of protein glycosylation in Golgi)","04144(Endocytosis)","K18442","NA","ADP ribosylation factor guanine nucleotide exchange factor 1 [Source:HGNC Symbol;Acc:HGNC:15772]",{"v":0.232365,"d":"0.23"},{"v":1.732225,"d":"1.73"},{"v":0.134142504582257,"d":"0.13"},{"v":-2.89816165083023,"d":"-2.90"},{"v":6.47983581335057e-05,"d":"0.00"},{"v":0.00174614522970289,"d":"0.00"},"down","yes"]
[156900,0,"chr5","+",96662237,96774683,"ENST00000395812",30,4506,"MSTRG.12236","CAST","GO:0003723(RNA binding);GO:0005783(endoplasmic reticulum);GO:0005829(cytosol);GO:0005515(protein binding);GO:0004869(cysteine-type endopeptidase inhibitor activity);GO:0030414(peptidase inhibitor activity);GO:0010466(negative regulation of peptidase activity);GO:0045296(cadherin binding);GO:0004866(endopeptidase inhibitor activity);GO:0016020(membrane);GO:2000675(negative regulation of type B pancreatic cell apoptotic process);GO:0010859(calcium-dependent cysteine-type endopeptidase inhibitor activity);GO:0097340(inhibition of cysteine-type endopeptidase activity)","NA","NA","NA","calpastatin [Source:HGNC Symbol;Acc:HGNC:1515]",{"v":1.887233,"d":"1.89"},{"v":0.268582,"d":"0.27"},{"v":7.02665480188546,"d":"7.03"},{"v":2.81283802509644,"d":"2.81"},{"v":6.54412255007813e-05,"d":"0.00"},{"v":1.76109217088895E-3,"d":"0.00"},"up","yes"]
[31391,0,"chr11","-",65775893,65780802,"ENST00000532090",2,4811,"MSTRG.2562","AP5B1","GO:0006810(transport);GO:0015031(protein transport);GO:0005765(lysosomal membrane);GO:0005515(protein binding);GO:0016197(endosomal transport);GO:0030119(AP-type membrane coat adaptor complex)","NA","NA","NA","adaptor related protein complex 5 beta 1 subunit [Source:HGNC Symbol;Acc:HGNC:25104]",{"v":1.8178,"d":"1.82"},{"v":13.128123,"d":"13.13"},{"v":0.138466100599454,"d":"0.14"},{"v":-2.85239527733663,"d":"-2.85"},{"v":6.63317506351816e-05,"d":"0.00"},{"v":1.7826546388739E-3,"d":"0.00"},"down","yes"]
[136974,0,"chr3","+",52198132,52214324,"ENST00000310271",11,2212,"MSTRG.10971","ALAS1","GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0016740(transferase activity);GO:0005739(mitochondrion);GO:0003824(catalytic activity);GO:0016746(transferase activity, transferring acyl groups);GO:0008152(metabolic process);GO:0009058(biosynthetic process);GO:0005515(protein binding);GO:0030170(pyridoxal phosphate binding);GO:0006783(heme biosynthetic process);GO:0005759(mitochondrial matrix);GO:0042802(identical protein binding);GO:0033014(tetrapyrrole biosynthetic process);GO:0006782(protoporphyrinogen IX biosynthetic process);GO:0003870(5-aminolevulinate synthase activity);GO:0006778(porphyrin-containing compound metabolic process);GO:0007005(mitochondrion organization);GO:0019216(regulation of lipid metabolic process)","00260(Glycine, serine and threonine metabolism);00860(Porphyrin and chlorophyll metabolism)","K00643","EC:2.3.1.37","5'-aminolevulinate synthase 1 [Source:HGNC Symbol;Acc:HGNC:396]",{"v":3.053617,"d":"3.05"},{"v":0.433282,"d":"0.43"},{"v":7.0476433362106,"d":"7.05"},{"v":2.81714091487974,"d":"2.82"},{"v":6.7282441640011e-05,"d":"0.00"},{"v":0.00180577391756417,"d":"0.00"},"up","yes"]
[88663,0,"chr17","+",77451244,77499024,"ENST00000591088",10,1691,"MSTRG.7267","SEPT9","GO:0005737(cytoplasm);GO:0005525(GTP binding);GO:0000166(nucleotide binding);GO:0051301(cell division);GO:0015629(actin cytoskeleton);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0007049(cell cycle);GO:0048471(perinuclear region of cytoplasm);GO:0005874(microtubule);GO:0045296(cadherin binding);GO:0051291(protein heterooligomerization);GO:0001725(stress fiber);GO:0003924(GTPase activity);GO:0005930(axoneme);GO:0031105(septin complex);GO:0097730(non-motile cilium);GO:1902857(positive regulation of non-motile cilium assembly)","05100(Bacterial invasion of epithelial cells)","K16938","NA","septin 9 [Source:HGNC Symbol;Acc:HGNC:7323]",{"v":11.309156,"d":"11.31"},{"v":81.006454,"d":"81.01"},{"v":0.139608086042132,"d":"0.14"},{"v":-2.8405455906246,"d":"-2.84"},{"v":6.79800832590293e-05,"d":"0.00"},{"v":0.0018220487282098,"d":"0.00"},"down","yes"]
[201295,0,"chrX","-",154487306,154490690,"ENST00000263512",2,2161,"ENSG00000126903","SLC10A3","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0055085(transmembrane transport);GO:0015293(symporter activity);GO:0015721(bile acid and bile salt transport);GO:0008508(bile acid:sodium symporter activity);GO:0010033(response to organic substance);GO:0032526(response to retinoic acid)","NA","NA","NA","solute carrier family 10 member 3 [Source:HGNC Symbol;Acc:HGNC:22979]",{"v":0.327929,"d":"0.33"},{"v":2.575357,"d":"2.58"},{"v":0.127333414357699,"d":"0.13"},{"v":-2.9733170393364,"d":"-2.97"},{"v":6.84944979480505e-05,"d":"0.00"},{"v":0.00183337551612155,"d":"0.00"},"down","yes"]
[128303,0,"chr22","+",17638584,17730855,"ENST00000618481",6,4961,"MSTRG.10109","BCL2L13","GO:0005634(nucleus);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0042981(regulation of apoptotic process);GO:0005739(mitochondrion);GO:0005515(protein binding);GO:0006915(apoptotic process);GO:0031966(mitochondrial membrane);GO:0008656(cysteine-type endopeptidase activator activity involved in apoptotic process);GO:0006919(activation of cysteine-type endopeptidase activity involved in apoptotic process)","04137(Mitophagy - animal);05134(Legionellosis)","K15485","NA","BCL2 like 13 [Source:HGNC Symbol;Acc:HGNC:17164]",{"v":1.256515,"d":"1.26"},{"v":0.177621,"d":"0.18"},{"v":7.07413537813659,"d":"7.07"},{"v":2.82255382824119,"d":"2.82"},{"v":6.89937165675818e-05,"d":"0.00"},{"v":1.84426577298725E-3,"d":"0.00"},"up","yes"]
[3164,0,"chr1","+",26696404,26780817,"ENST00000457599",20,6268,"MSTRG.286","ARID1A","GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0003677(DNA binding);GO:0006338(chromatin remodeling);GO:0090544(BAF-type complex);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0016569(covalent chromatin modification);GO:0005515(protein binding);GO:0007399(nervous system development);GO:0045893(positive regulation of transcription, DNA-templated);GO:0003713(transcription coactivator activity);GO:0000790(nuclear chromatin);GO:0030521(androgen receptor signaling pathway);GO:0016922(ligand-dependent nuclear receptor binding);GO:0031491(nucleosome binding);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0001704(formation of primary germ layer);GO:0001843(neural tube closure);GO:0003205(cardiac chamber development);GO:0003408(optic cup formation involved in camera-type eye development);GO:0006325(chromatin organization);GO:0006337(nucleosome disassembly);GO:0006344(maintenance of chromatin silencing);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0007369(gastrulation);GO:0007566(embryo implantation);GO:0019827(stem cell population maintenance);GO:0030520(intracellular estrogen receptor signaling pathway);GO:0030900(forebrain development);GO:0042766(nucleosome mobilization);GO:0042921(glucocorticoid receptor signaling pathway);GO:0043044(ATP-dependent chromatin remodeling);GO:0048096(chromatin-mediated maintenance of transcription);GO:0055007(cardiac muscle cell differentiation);GO:0060674(placenta blood vessel development);GO:1901998(toxin transport);GO:0016514(SWI/SNF complex);GO:0071564(npBAF complex);GO:0071565(nBAF complex)","05225(Hepatocellular carcinoma)","K11653","NA","AT-rich interaction domain 1A [Source:HGNC Symbol;Acc:HGNC:11110]",{"v":0.494521,"d":"0.49"},{"v":3.591221,"d":"3.59"},{"v":0.137702747895493,"d":"0.14"},{"v":-2.86037074575838,"d":"-2.86"},{"v":7.04434578998431E-5,"d":"0.00"},{"v":0.00187872350877361,"d":"0.00"},"down","yes"]
[149674,0,"chr4","-",102261666,102345139,"ENST00000394833",8,3238,"ENSG00000138821","SLC39A8","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0055085(transmembrane transport);GO:0006811(ion transport);GO:0046873(metal ion transmembrane transporter activity);GO:0030001(metal ion transport);GO:0005886(plasma membrane);GO:0005887(integral component of plasma membrane);GO:0005385(zinc ion transmembrane transporter activity);GO:0031090(organelle membrane);GO:0006829(zinc II ion transport);GO:0006882(cellular zinc ion homeostasis);GO:0071578(zinc II ion transmembrane import);GO:0070574(cadmium ion transmembrane transport)","04216(Ferroptosis)","K14714","NA","solute carrier family 39 member 8 [Source:HGNC Symbol;Acc:HGNC:20862]",{"v":1.696634,"d":"1.70"},{"v":0.238644,"d":"0.24"},{"v":7.10947687769229,"d":"7.11"},{"v":2.8297434088286,"d":"2.83"},{"v":7.04709489218467e-05,"d":"0.00"},{"v":0.00187872350877361,"d":"0.00"},"up","yes"]
[58085,0,"chr14","-",94378373,94388847,"ENST00000636712",6,1485,"MSTRG.4639","SERPINA1","GO:0005615(extracellular space);GO:0043231(intracellular membrane-bounded organelle);GO:0005794(Golgi apparatus);GO:0010951(negative regulation of endopeptidase activity);GO:0005783(endoplasmic reticulum);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0005578(proteinaceous extracellular matrix);GO:0030414(peptidase inhibitor activity);GO:0010466(negative regulation of peptidase activity);GO:0042802(identical protein binding);GO:0000139(Golgi membrane);GO:0070062(extracellular exosome);GO:0044267(cellular protein metabolic process);GO:0043687(post-translational protein modification);GO:0004867(serine-type endopeptidase inhibitor activity);GO:0043312(neutrophil degranulation);GO:0006953(acute-phase response);GO:0002576(platelet degranulation);GO:0002020(protease binding);GO:1904813(ficolin-1-rich granule lumen);GO:0007596(blood coagulation);GO:0007599(hemostasis);GO:0005788(endoplasmic reticulum lumen);GO:0031093(platelet alpha granule lumen);GO:0006888(ER to Golgi vesicle-mediated transport);GO:0048208(COPII vesicle coating);GO:0033116(endoplasmic reticulum-Golgi intermediate compartment membrane);GO:0030134(ER to Golgi transport vesicle)","04610(Complement and coagulation cascades)","K03984","NA","serpin family A member 1 [Source:HGNC Symbol;Acc:HGNC:8941]",{"v":2.853831,"d":"2.85"},{"v":20.574362,"d":"20.57"},{"v":0.138708116441229,"d":"0.14"},{"v":-2.84987588612336,"d":"-2.85"},{"v":7.15292557563682e-05,"d":"0.00"},{"v":0.00190439490525755,"d":"0.00"},"down","yes"]
[124731,"j","chr20","-",53567073,53609847,"MSTRG.9839.2",8,5968,"MSTRG.9839","ZNF217","NA","NA","NA","NA","NA",{"v":1.067169,"d":"1.07"},{"v":7.631581,"d":"7.63"},{"v":0.139835900319999,"d":"0.14"},{"v":-2.83819330095099,"d":"-2.84"},{"v":7.23644506888245e-05,"d":"0.00"},{"v":1.92406571418702E-3,"d":"0.00"},"down","yes"]
[105432,0,"chr19","-",54217120,54220790,"ENST00000469273",8,902,"MSTRG.8412","LILRB3","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005886(plasma membrane);GO:0002376(immune system process);GO:0002250(adaptive immune response);GO:0005515(protein binding);GO:0005887(integral component of plasma membrane);GO:0043312(neutrophil degranulation);GO:0004872(receptor activity);GO:0045671(negative regulation of osteoclast differentiation);GO:0007166(cell surface receptor signaling pathway);GO:0030667(secretory granule membrane);GO:0004888(transmembrane signaling receptor activity);GO:0006952(defense response)","04662(B cell receptor signaling pathway);04380(Osteoclast differentiation)","NA","NA","leukocyte immunoglobulin like receptor B3 [Source:HGNC Symbol;Acc:HGNC:6607]",{"v":1.974803,"d":"1.97"},{"v":14.510482,"d":"14.51"},{"v":0.13609492779082,"d":"0.14"},{"v":-2.87731479577059,"d":"-2.88"},{"v":7.27863528070462e-05,"d":"0.00"},{"v":0.00193150405706111,"d":"0.00"},"down","yes"]
[74521,0,"chr16","+",67541347,67546786,"ENST00000569733",11,3370,"MSTRG.6027","RIPOR1","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005794(Golgi apparatus);GO:0005515(protein binding);GO:0003674(molecular_function);GO:0008150(biological_process);GO:0070062(extracellular exosome);GO:0009267(cellular response to starvation);GO:0030335(positive regulation of cell migration);GO:0051683(establishment of Golgi localization);GO:0007266(Rho protein signal transduction);GO:0090316(positive regulation of intracellular protein transport);GO:0071889(14-3-3 protein binding);GO:0009611(response to wounding);GO:0034067(protein localization to Golgi apparatus);GO:0012506(vesicle membrane)","NA","NA","NA","RHO family interacting cell polarization regulator 1 [Source:HGNC Symbol;Acc:HGNC:25836]",{"v":0.309008,"d":"0.31"},{"v":2.335871,"d":"2.34"},{"v":0.132288127212504,"d":"0.13"},{"v":-2.91824450855625,"d":"-2.92"},{"v":7.28376680171784e-05,"d":"0.00"},{"v":0.00193150405706111,"d":"0.00"},"down","yes"]
[102948,0,"chr19","-",45818955,45855710,"ENST00000599814",21,6537,"MSTRG.8238","SYMPK","GO:0006397(mRNA processing);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0007155(cell adhesion);GO:0005886(plasma membrane);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0030054(cell junction);GO:0005923(bicellular tight junction);GO:0006369(termination of RNA polymerase II transcription);GO:0031124(mRNA 3'-end processing);GO:0000398(mRNA splicing, via spliceosome);GO:0006406(mRNA export from nucleus);GO:0006378(mRNA polyadenylation);GO:0097165(nuclear stress granule);GO:0035307(positive regulation of protein dephosphorylation)","03015(mRNA surveillance pathway);04530(Tight junction)","NA","NA","symplekin [Source:HGNC Symbol;Acc:HGNC:22935]",{"v":1.638856,"d":"1.64"},{"v":0.241658,"d":"0.24"},{"v":6.78171630982628,"d":"6.78"},{"v":2.76165043535611,"d":"2.76"},{"v":7.3088343458188e-05,"d":"0.00"},{"v":0.00193558095778925,"d":"0.00"},"up","yes"]
[145730,0,"chr4","-",6707701,6709880,"ENST00000320848",2,1593,"MSTRG.11516","MRFAP1L1","GO:0005515(protein binding);GO:0042802(identical protein binding)","NA","NA","NA","Morf4 family associated protein 1 like 1 [Source:HGNC Symbol;Acc:HGNC:28796]",{"v":25.65645,"d":"25.66"},{"v":3.889491,"d":"3.89"},{"v":6.59635155345519,"d":"6.60"},{"v":2.72166828945321,"d":"2.72"},{"v":7.34535465119226e-05,"d":"0.00"},{"v":1.94267604867559E-3,"d":"0.00"},"up","yes"]
[151615,"o","chr4","+",153684275,153709588,"MSTRG.11892.2",4,6906,"MSTRG.11892","TLR2","NA","NA","NA","NA","NA",{"v":1.75189,"d":"1.75"},{"v":12.409089,"d":"12.41"},{"v":0.141177970437636,"d":"0.14"},{"v":-2.82441310840214,"d":"-2.82"},{"v":7.48006636178731e-05,"d":"0.00"},{"v":0.00197568736920858,"d":"0.00"},"down","yes"]
[105413,0,"chr19","+",54200742,54207647,"ENST00000302907",5,829,"MSTRG.8410","RPS9","GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0006412(translation);GO:0030529(intracellular ribonucleoprotein complex);GO:0005622(intracellular);GO:0003735(structural constituent of ribosome);GO:0005840(ribosome);GO:0015935(small ribosomal subunit);GO:0005515(protein binding);GO:0022627(cytosolic small ribosomal subunit);GO:0019843(rRNA binding);GO:0005730(nucleolus);GO:0005925(focal adhesion);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0008284(positive regulation of cell proliferation);GO:0006413(translational initiation);GO:0006364(rRNA processing);GO:0000184(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay);GO:0019083(viral transcription);GO:0006614(SRP-dependent cotranslational protein targeting to membrane);GO:0045182(translation regulator activity);GO:0045903(positive regulation of translational fidelity)","03010(Ribosome)","K02997","NA","ribosomal protein S9 [Source:HGNC Symbol;Acc:HGNC:10442]",{"v":7.675968,"d":"7.68"},{"v":54.654408,"d":"54.65"},{"v":0.140445542837094,"d":"0.14"},{"v":-2.83191725489337,"d":"-2.83"},{"v":7.54502634752518e-05,"d":"0.00"},{"v":0.00199021249811602,"d":"0.00"},"down","yes"]
[65604,0,"chr15","+",81299416,81306852,"ENST00000558332",5,2020,"MSTRG.5358","IL16","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016607(nuclear speck);GO:0005829(cytosol);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0005886(plasma membrane);GO:0005576(extracellular region);GO:0005125(cytokine activity);GO:0005615(extracellular space);GO:0006935(chemotaxis);GO:0016032(viral process);GO:0006955(immune response);GO:0051924(regulation of calcium ion transport);GO:0042609(CD4 receptor binding);GO:0030595(leukocyte chemotaxis);GO:0050930(induction of positive chemotaxis);GO:0005622(intracellular)","NA","NA","NA","interleukin 16 [Source:HGNC Symbol;Acc:HGNC:5980]",{"v":30.207691,"d":"30.21"},{"v":4.617909,"d":"4.62"},{"v":6.54142188596614,"d":"6.54"},{"v":2.70960426337913,"d":"2.71"},{"v":7.58130278174108e-05,"d":"0.00"},{"v":0.00199714319189717,"d":"0.00"},"up","yes"]
[95622,0,"chr19","+",6887566,6940459,"ENST00000250572",20,2939,"MSTRG.7744","ADGRE1","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0004930(G-protein coupled receptor activity);GO:0007186(G-protein coupled receptor signaling pathway);GO:0005509(calcium ion binding);GO:0005886(plasma membrane);GO:0004871(signal transducer activity);GO:0007165(signal transduction);GO:0004888(transmembrane signaling receptor activity);GO:0007166(cell surface receptor signaling pathway);GO:0002376(immune system process);GO:0002250(adaptive immune response);GO:0005887(integral component of plasma membrane);GO:0007155(cell adhesion);GO:0009897(external side of plasma membrane);GO:0071944(cell periphery)","NA","NA","NA","adhesion G protein-coupled receptor E1 [Source:HGNC Symbol;Acc:HGNC:3336]",{"v":4.824461,"d":"4.82"},{"v":0.725199,"d":"0.73"},{"v":6.65260294071007,"d":"6.65"},{"v":2.73391892932159,"d":"2.73"},{"v":7.65509294406999e-05,"d":"0.00"},{"v":0.00201251540344132,"d":"0.00"},"up","yes"]
[79799,"j","chr17","-",16031404,16215457,"MSTRG.6470.4",46,8072,"MSTRG.6470","NCOR1","NA","NA","NA","NA","NA",{"v":1.339552,"d":"1.34"},{"v":0.197949,"d":"0.20"},{"v":6.76715719705581,"d":"6.77"},{"v":2.75854990188851,"d":"2.76"},{"v":7.65981423585437e-05,"d":"0.00"},{"v":0.00201251540344132,"d":"0.00"},"up","yes"]
[2003,0,"chr1","+",16367083,16398142,"ENST00000401088",4,3636,"MSTRG.187","SZRD1","NA","NA","NA","NA","SUZ RNA binding domain containing 1 [Source:HGNC Symbol;Acc:HGNC:30232]",{"v":0.591082,"d":"0.59"},{"v":4.282971,"d":"4.28"},{"v":0.138007471916107,"d":"0.14"},{"v":-2.85718171625715,"d":"-2.86"},{"v":7.68288902696104e-05,"d":"0.00"},{"v":0.00201405915807344,"d":"0.00"},"down","yes"]
[181929,0,"chr8","+",22059206,22082518,"ENST00000523266",16,2735,"MSTRG.14210","DMTN","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0003779(actin binding);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0051693(actin filament capping);GO:0005856(cytoskeleton);GO:0042995(cell projection);GO:0005515(protein binding);GO:0048471(perinuclear region of cytoplasm);GO:0031410(cytoplasmic vesicle);GO:0007010(cytoskeleton organization);GO:0032956(regulation of actin cytoskeleton organization);GO:0055085(transmembrane transport);GO:0012505(endomembrane system);GO:0005102(receptor binding);GO:0008360(regulation of cell shape);GO:0051017(actin filament bundle assembly);GO:0030036(actin cytoskeleton organization);GO:0005884(actin filament);GO:0051895(negative regulation of focal adhesion assembly);GO:0090315(negative regulation of protein targeting to membrane);GO:1900025(negative regulation of substrate adhesion-dependent cell spreading);GO:0006461(protein complex assembly);GO:0015629(actin cytoskeleton);GO:0071320(cellular response to cAMP);GO:0071277(cellular response to calcium ion);GO:0035584(calcium-mediated signaling using intracellular calcium source);GO:0051489(regulation of filopodium assembly);GO:1900026(positive regulation of substrate adhesion-dependent cell spreading);GO:0090303(positive regulation of wound healing);GO:0090527(actin filament reorganization);GO:2001046(positive regulation of integrin-mediated signaling pathway);GO:0033137(negative regulation of peptidyl-serine phosphorylation);GO:0030507(spectrin binding);GO:0010591(regulation of lamellipodium assembly);GO:0048821(erythrocyte development);GO:0010763(positive regulation of fibroblast migration);GO:0010801(negative regulation of peptidyl-threonine phosphorylation);GO:0010812(negative regulation of cell-substrate adhesion);GO:0030194(positive regulation of blood coagulation);GO:0035585(calcium-mediated signaling using extracellular calcium source);GO:0050732(negative regulation of peptidyl-tyrosine phosphorylation);GO:0070560(protein secretion by platelet);GO:1901731(positive regulation of platelet aggregation);GO:0014731(spectrin-associated cytoskeleton);GO:0031095(platelet dense tubular network membrane);GO:0031253(cell projection membrane);GO:0043621(protein self-association);GO:0014069(postsynaptic density);GO:0030863(cortical cytoskeleton)","NA","NA","NA","dematin actin binding protein [Source:HGNC Symbol;Acc:HGNC:3382]",{"v":20.277153,"d":"20.28"},{"v":3.101656,"d":"3.10"},{"v":6.53752479320724,"d":"6.54"},{"v":2.70874451271244,"d":"2.71"},{"v":7.69179874910185e-05,"d":"0.00"},{"v":0.00201405915807344,"d":"0.00"},"up","yes"]
[13826,0,"chr1","-",175012958,175023425,"ENST00000476371",3,2115,"MSTRG.1207","MRPS14","GO:0003723(RNA binding);GO:0006412(translation);GO:0030529(intracellular ribonucleoprotein complex);GO:0005622(intracellular);GO:0003735(structural constituent of ribosome);GO:0005840(ribosome);GO:0005739(mitochondrion);GO:0005743(mitochondrial inner membrane);GO:0070125(mitochondrial translational elongation);GO:0070126(mitochondrial translational termination);GO:0005763(mitochondrial small ribosomal subunit);GO:0005761(mitochondrial ribosome)","03010(Ribosome)","K02954","NA","mitochondrial ribosomal protein S14 [Source:HGNC Symbol;Acc:HGNC:14049]",{"v":0.388371,"d":"0.39"},{"v":2.939487,"d":"2.94"},{"v":0.132122033538505,"d":"0.13"},{"v":-2.92005701493376,"d":"-2.92"},{"v":7.69594920678104E-5,"d":"0.00"},{"v":0.00201405915807344,"d":"0.00"},"down","yes"]
[146809,"j","chr4","-",39454124,39458925,"MSTRG.11579.1",8,885,"MSTRG.11579","RPL9","NA","NA","NA","NA","NA",{"v":6.529647,"d":"6.53"},{"v":46.405754,"d":"46.41"},{"v":0.140707701894037,"d":"0.14"},{"v":-2.82922679559349,"d":"-2.83"},{"v":7.74194295049362E-5,"d":"0.00"},{"v":0.00202344393763687,"d":"0.00"},"down","yes"]
[46515,"j","chr12","+",109999537,110039432,"MSTRG.3704.4",15,3800,"MSTRG.3704","ANKRD13A","NA","NA","NA","NA","NA",{"v":1.290821,"d":"1.29"},{"v":9.182442,"d":"9.18"},{"v":0.140574914603327,"d":"0.14"},{"v":-2.83058892441906,"d":"-2.83"},{"v":7.75396505107492e-05,"d":"0.00"},{"v":2.02393691686097E-3,"d":"0.00"},"down","yes"]
[154429,0,"chr5","-",40762770,40798374,"ENST00000354209",10,1918,"MSTRG.12019","PRKAA1","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016607(nuclear speck);GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0005829(cytosol);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0016569(covalent chromatin modification);GO:0006629(lipid metabolic process);GO:0006631(fatty acid metabolic process);GO:0006633(fatty acid biosynthetic process);GO:0006694(steroid biosynthetic process);GO:0008202(steroid metabolic process);GO:0016126(sterol biosynthetic process);GO:0005515(protein binding);GO:0048511(rhythmic process);GO:0016055(Wnt signaling pathway);GO:0006914(autophagy);GO:0008203(cholesterol metabolic process);GO:0006695(cholesterol biosynthetic process);GO:0005654(nucleoplasm);GO:0010508(positive regulation of autophagy);GO:0010628(positive regulation of gene expression);GO:0005622(intracellular);GO:0003682(chromatin binding);GO:0001666(response to hypoxia);GO:0043066(negative regulation of apoptotic process);GO:0007165(signal transduction);GO:0010332(response to gamma radiation);GO:1901796(regulation of signal transduction by p53 class mediator);GO:0032007(negative regulation of TOR signaling);GO:2000505(regulation of energy homeostasis);GO:0045821(positive regulation of glycolytic process);GO:0035404(histone-serine phosphorylation);GO:0042752(regulation of circadian rhythm);GO:0000187(activation of MAPK activity);GO:0042593(glucose homeostasis);GO:0042149(cellular response to glucose starvation);GO:0007050(cell cycle arrest);GO:0016241(regulation of macroautophagy);GO:0004679(AMP-activated protein kinase activity);GO:0016236(macroautophagy);GO:0031588(nucleotide-activated protein kinase complex);GO:0031669(cellular response to nutrient levels);GO:0050321(tau-protein kinase activity);GO:0004691(cAMP-dependent protein kinase activity);GO:0055089(fatty acid homeostasis);GO:0008610(lipid biosynthetic process);GO:0035174(histone serine kinase activity);GO:0047322([hydroxymethylglutaryl-CoA reductase (NADPH)] kinase activity);GO:0050405([acetyl-CoA carboxylase] kinase activity);GO:0045542(positive regulation of cholesterol biosynthetic process);GO:0046318(negative regulation of glucosylceramide biosynthetic process);GO:0050995(negative regulation of lipid catabolic process);GO:0061762(CAMKK-AMPK signaling cascade);GO:0008022(protein C-terminus binding);GO:0019900(kinase binding);GO:0006006(glucose metabolic process);GO:0008284(positive regulation of cell proliferation);GO:0009411(response to UV);GO:0009631(cold acclimation);GO:0014823(response to activity);GO:0019395(fatty acid oxidation);GO:0031000(response to caffeine);GO:0033135(regulation of peptidyl-serine phosphorylation);GO:0042542(response to hydrogen peroxide);GO:0048643(positive regulation of skeletal muscle tissue development);GO:0051291(protein heterooligomerization);GO:0060627(regulation of vesicle-mediated transport);GO:0070301(cellular response to hydrogen peroxide);GO:0071361(cellular response to ethanol);GO:0071380(cellular response to prostaglandin E stimulus);GO:0071417(cellular response to organonitrogen compound);GO:0071456(cellular response to hypoxia);GO:1901563(response to camptothecin);GO:2001274(negative regulation of glucose import in response to insulin stimulus);GO:0016324(apical plasma membrane);GO:0043234(protein complex)","04371(Apelin signaling pathway);04068(FoxO signaling pathway);04151(PI3K-Akt signaling pathway);04152(AMPK signaling pathway);04150(mTOR signaling pathway);04140(Autophagy - animal);04530(Tight junction);04910(Insulin signaling pathway);04922(Glucagon signaling pathway);04920(Adipocytokine signaling pathway);04921(Oxytocin signaling pathway);04211(Longevity regulating pathway - mammal);04213(Longevity regulating pathway - multiple species);04710(Circadian rhythm);05418(Fluid shear stress and atherosclerosis);05410(Hypertrophic cardiomyopathy (HCM));04932(Non-alcoholic fatty liver disease (NAFLD));04931(Insulin resistance)","K07198","EC:2.7.11.11","protein kinase AMP-activated catalytic subunit alpha 1 [Source:HGNC Symbol;Acc:HGNC:9376]",{"v":9.535655,"d":"9.54"},{"v":1.444482,"d":"1.44"},{"v":6.60143567036488,"d":"6.60"},{"v":2.72277981375517,"d":"2.72"},{"v":7.82776618285987e-05,"d":"0.00"},{"v":0.00203962566623535,"d":"0.00"},"up","yes"]
[22572,0,"chr10","+",96832298,96995959,"ENST00000421806",8,16004,"ENSG00000196233","LCOR","GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0005515(protein binding)","NA","NA","NA","ligand dependent nuclear receptor corepressor [Source:HGNC Symbol;Acc:HGNC:29503]",{"v":1.178504,"d":"1.18"},{"v":0.178087,"d":"0.18"},{"v":6.61757455625621,"d":"6.62"},{"v":2.72630254379475,"d":"2.73"},{"v":7.83449962941966e-05,"d":"0.00"},{"v":0.00203962566623535,"d":"0.00"},"up","yes"]
[126792,0,"chr21","+",33718810,33817614,"ENST00000399338",21,3115,"MSTRG.10040","ITSN1","GO:0016020(membrane);GO:0046872(metal ion binding);GO:0035556(intracellular signal transduction);GO:0005509(calcium ion binding);GO:0005886(plasma membrane);GO:0005089(Rho guanyl-nucleotide exchange factor activity);GO:0035023(regulation of Rho protein signal transduction);GO:0043547(positive regulation of GTPase activity);GO:0042995(cell projection);GO:0005515(protein binding);GO:0030054(cell junction);GO:0045202(synapse);GO:0005905(clathrin-coated pit);GO:0005085(guanyl-nucleotide exchange factor activity);GO:0005829(cytosol);GO:0006897(endocytosis);GO:0030027(lamellipodium);GO:0051056(regulation of small GTPase mediated signal transduction);GO:0061024(membrane organization);GO:0012505(endomembrane system);GO:0016032(viral process);GO:0043005(neuron projection);GO:0070064(proline-rich region binding);GO:0048013(ephrin receptor signaling pathway);GO:0043065(positive regulation of apoptotic process);GO:0032947(protein complex scaffold);GO:0042327(positive regulation of phosphorylation);GO:0048488(synaptic vesicle endocytosis);GO:0019209(kinase activator activity);GO:0007264(small GTPase mediated signal transduction);GO:0043524(negative regulation of neuron apoptotic process);GO:0051897(positive regulation of protein kinase B signaling);GO:0030139(endocytic vesicle);GO:0005524(ATP binding);GO:0006750(glutathione biosynthetic process);GO:0004363(glutathione synthase activity);GO:0016021(integral component of membrane)","NA","NA","NA","intersectin 1 [Source:HGNC Symbol;Acc:HGNC:6183]",{"v":0.198815,"d":"0.20"},{"v":1.538121,"d":"1.54"},{"v":0.129258361338282,"d":"0.13"},{"v":-2.95167048768478,"d":"-2.95"},{"v":7.8555284446877e-05,"d":"0.00"},{"v":2.04230066880945E-3,"d":"0.00"},"down","yes"]
[197099,0,"chrX","-",48914104,48914914,"ENST00000485431",2,711,"MSTRG.15282","PIM2","GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0008637(apoptotic mitochondrial changes);GO:0010508(positive regulation of autophagy);GO:0016239(positive regulation of macroautophagy);GO:0032091(negative regulation of protein binding);GO:0043066(negative regulation of apoptotic process);GO:0043123(positive regulation of I-kappaB kinase/NF-kappaB signaling);GO:0045893(positive regulation of transcription, DNA-templated);GO:0050821(protein stabilization);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0005515(protein binding);GO:0007049(cell cycle);GO:0006915(apoptotic process);GO:0005737(cytoplasm);GO:0008285(negative regulation of cell proliferation);GO:0009615(response to virus);GO:0008283(cell proliferation);GO:0007346(regulation of mitotic cell cycle);GO:0000082(G1/S transition of mitotic cell cycle);GO:0046777(protein autophosphorylation);GO:0007140(male meiotic nuclear division)","05200(Pathways in cancer);05221(Acute myeloid leukemia)","NA","NA","Pim-2 proto-oncogene, serine/threonine kinase [Source:HGNC Symbol;Acc:HGNC:8987]",{"v":9.088883,"d":"9.09"},{"v":1.3015,"d":"1.30"},{"v":6.98339070303496,"d":"6.98"},{"v":2.80392769011624,"d":"2.80"},{"v":7.86523044027678e-05,"d":"0.00"},{"v":2.04230066880945E-3,"d":"0.00"},"up","yes"]
[201079,0,"chrX","-",153947559,153971184,"ENST00000369984",26,8375,"MSTRG.15492","HCFC1","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0006355(regulation of transcription, DNA-templated);GO:0016569(covalent chromatin modification);GO:0005515(protein binding);GO:0007049(cell cycle);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0003713(transcription coactivator activity);GO:0042802(identical protein binding);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0005654(nucleoplasm);GO:0045296(cadherin binding);GO:0043254(regulation of protein complex assembly);GO:0050821(protein stabilization);GO:0010628(positive regulation of gene expression);GO:0016579(protein deubiquitination);GO:0003682(chromatin binding);GO:0016032(viral process);GO:0006366(transcription from RNA polymerase II promoter);GO:0071339(MLL1 complex);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0007005(mitochondrion organization);GO:0048188(Set1C/COMPASS complex);GO:0045787(positive regulation of cell cycle);GO:0043995(histone acetyltransferase activity (H4-K5 specific));GO:0043996(histone acetyltransferase activity (H4-K8 specific));GO:0046972(histone acetyltransferase activity (H4-K16 specific));GO:0043981(histone H4-K5 acetylation);GO:0043982(histone H4-K8 acetylation);GO:0043984(histone H4-K16 acetylation);GO:0000123(histone acetyltransferase complex);GO:0005671(Ada2/Gcn5/Ada3 transcription activator complex);GO:0043025(neuronal cell body);GO:0033613(activating transcription factor binding);GO:0070461(SAGA-type complex);GO:0001205(transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding);GO:0019046(release from viral latency);GO:0071407(cellular response to organic cyclic compound);GO:0030424(axon);GO:0030425(dendrite)","05168(Herpes simplex infection)","K14966","NA","host cell factor C1 [Source:HGNC Symbol;Acc:HGNC:4839]",{"v":0.309204,"d":"0.31"},{"v":2.217948,"d":"2.22"},{"v":0.139409941080675,"d":"0.14"},{"v":-2.8425946539362,"d":"-2.84"},{"v":7.96008187148684e-05,"d":"0.00"},{"v":0.00206424564688116,"d":"0.00"},"down","yes"]
[12952,"j","chr1","+",161505451,161596728,"MSTRG.1158.14",7,1926,"MSTRG.1158","FCGR2A","NA","NA","NA","NA","NA",{"v":0.650327,"d":"0.65"},{"v":4.751389,"d":"4.75"},{"v":0.136870923428917,"d":"0.14"},{"v":-2.86911209884181,"d":"-2.87"},{"v":8.20750775462662e-05,"d":"0.00"},{"v":0.00212564870096478,"d":"0.00"},"down","yes"]
[31288,0,"chr11","+",65576046,65585417,"ENST00000533237",12,2267,"MSTRG.2551","EHBP1L1","GO:0016020(membrane);GO:0005768(endosome);GO:0003674(molecular_function);GO:0008150(biological_process)","NA","NA","NA","EH domain binding protein 1 like 1 [Source:HGNC Symbol;Acc:HGNC:30682]",{"v":0.331613,"d":"0.33"},{"v":2.501662,"d":"2.50"},{"v":0.132557076055838,"d":"0.13"},{"v":-2.91531440983354,"d":"-2.92"},{"v":8.27820040213814e-05,"d":"0.00"},{"v":0.00213919618243254,"d":"0.00"},"down","yes"]
[22698,0,"chr10","+",97737123,97760907,"ENST00000393677",13,3047,"MSTRG.1895","ZFYVE27","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0046872(metal ion binding);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005886(plasma membrane);GO:0042995(cell projection);GO:0005515(protein binding);GO:0030425(dendrite);GO:0016192(vesicle-mediated transport);GO:0005768(endosome);GO:0030424(axon);GO:0045773(positive regulation of axon extension);GO:0055038(recycling endosome membrane);GO:0030176(integral component of endoplasmic reticulum membrane);GO:0031175(neuron projection development);GO:0043621(protein self-association);GO:0072659(protein localization to plasma membrane);GO:0071787(endoplasmic reticulum tubular network formation);GO:0048011(neurotrophin TRK receptor signaling pathway);GO:0032584(growth cone membrane);GO:0071782(endoplasmic reticulum tubular network);GO:0005737(cytoplasm)","04144(Endocytosis)","K19368","NA","zinc finger FYVE-type containing 27 [Source:HGNC Symbol;Acc:HGNC:26559]",{"v":1.529089,"d":"1.53"},{"v":0.220664,"d":"0.22"},{"v":6.92949008447232,"d":"6.93"},{"v":2.79274919368004,"d":"2.79"},{"v":8.2812432342766e-05,"d":"0.00"},{"v":0.00213919618243254,"d":"0.00"},"up","yes"]
[107811,0,"chr2","+",24584541,24770702,"ENST00000395856",21,6828,"MSTRG.8537","NCOA1","GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0005634(nucleus);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0016740(transferase activity);GO:0003713(transcription coactivator activity);GO:0046983(protein dimerization activity);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0016746(transferase activity, transferring acyl groups);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0004402(histone acetyltransferase activity);GO:0030374(ligand-dependent nuclear receptor transcription coactivator activity);GO:0045893(positive regulation of transcription, DNA-templated);GO:0032870(cellular response to hormone stimulus);GO:0035257(nuclear hormone receptor binding);GO:0047485(protein N-terminus binding);GO:0019899(enzyme binding);GO:0000790(nuclear chromatin);GO:0017162(aryl hydrocarbon receptor binding);GO:0043234(protein complex);GO:0030521(androgen receptor signaling pathway);GO:0016922(ligand-dependent nuclear receptor binding);GO:0019216(regulation of lipid metabolic process);GO:0015721(bile acid and bile salt transport);GO:0050681(androgen receptor binding);GO:0001105(RNA polymerase II transcription coactivator activity);GO:0030522(intracellular receptor signaling pathway);GO:0001012(RNA polymerase II regulatory region DNA binding);GO:0003677(DNA binding);GO:0003682(chromatin binding);GO:0008134(transcription factor binding);GO:0030331(estrogen receptor binding);GO:0032403(protein complex binding);GO:0033142(progesterone receptor binding);GO:0042974(retinoic acid receptor binding);GO:0046965(retinoid X receptor binding);GO:0000435(positive regulation of transcription from RNA polymerase II promoter by galactose);GO:0002155(regulation of thyroid hormone mediated signaling pathway);GO:0007595(lactation);GO:0008584(male gonad development);GO:0009725(response to hormone);GO:0021549(cerebellum development);GO:0021766(hippocampus development);GO:0021854(hypothalamus development);GO:0021987(cerebral cortex development);GO:0032355(response to estradiol);GO:0032526(response to retinoic acid);GO:0032570(response to progesterone);GO:0043065(positive regulation of apoptotic process);GO:0043967(histone H4 acetylation);GO:0044849(estrous cycle);GO:0045666(positive regulation of neuron differentiation);GO:0045925(positive regulation of female receptivity);GO:0060179(male mating behavior);GO:0060713(labyrinthine layer morphogenesis);GO:1904017(cellular response to Thyroglobulin triiodothyronine);GO:2001038(regulation of cellular response to drug);GO:2001141(regulation of RNA biosynthetic process);GO:0005737(cytoplasm);GO:0043005(neuron projection)","04919(Thyroid hormone signaling pathway);05200(Pathways in cancer);05224(Breast cancer)","K09101","EC:2.3.1.48","nuclear receptor coactivator 1 [Source:HGNC Symbol;Acc:HGNC:7668]",{"v":1.520849,"d":"1.52"},{"v":10.652599,"d":"10.65"},{"v":0.142767882279245,"d":"0.14"},{"v":-2.80825663434427,"d":"-2.81"},{"v":8.30913184123005e-05,"d":"0.00"},{"v":2.14362719128788E-3,"d":"0.00"},"down","yes"]
[47351,0,"chr12","-",120196702,120201107,"ENST00000313104",7,912,"MSTRG.3785","RPLP0","GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0006412(translation);GO:0005783(endoplasmic reticulum);GO:0005829(cytosol);GO:0030529(intracellular ribonucleoprotein complex);GO:0005622(intracellular);GO:0005840(ribosome);GO:0005515(protein binding);GO:0003735(structural constituent of ribosome);GO:0042254(ribosome biogenesis);GO:0005925(focal adhesion);GO:0070062(extracellular exosome);GO:0016032(viral process);GO:0022625(cytosolic large ribosomal subunit);GO:0035722(interleukin-12-mediated signaling pathway);GO:0006413(translational initiation);GO:0006364(rRNA processing);GO:0036464(cytoplasmic ribonucleoprotein granule);GO:0000184(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay);GO:0019083(viral transcription);GO:0006614(SRP-dependent cotranslational protein targeting to membrane)","03010(Ribosome)","NA","NA","ribosomal protein lateral stalk subunit P0 [Source:HGNC Symbol;Acc:HGNC:10371]",{"v":31.109612,"d":"31.11"},{"v":4.771518,"d":"4.77"},{"v":6.51985636436874,"d":"6.52"},{"v":2.70484018152759,"d":"2.70"},{"v":8.3537909418526e-05,"d":"0.00"},{"v":0.00215236771002468,"d":"0.00"},"up","yes"]
[66129,0,"chr15","+",88621296,88632282,"ENST00000332810",4,3117,"ENSG00000181026","AEN","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0005730(nucleolus);GO:0016787(hydrolase activity);GO:0031965(nuclear membrane);GO:0090305(nucleic acid phosphodiester bond hydrolysis);GO:0005515(protein binding);GO:0006974(cellular response to DNA damage stimulus);GO:0006915(apoptotic process);GO:0004527(exonuclease activity);GO:0004518(nuclease activity);GO:0005654(nucleoplasm);GO:0042771(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator);GO:0010212(response to ionizing radiation)","NA","NA","NA","apoptosis enhancing nuclease [Source:HGNC Symbol;Acc:HGNC:25722]",{"v":2.205238,"d":"2.21"},{"v":0.322399,"d":"0.32"},{"v":6.84008945437176,"d":"6.84"},{"v":2.77401519273319,"d":"2.77"},{"v":8.44479400798868e-05,"d":"0.00"},{"v":0.00217301091174636,"d":"0.00"},"up","yes"]
[120122,0,"chr2","+",231708509,231713541,"ENST00000409115",5,1221,"MSTRG.9493","PTMA","GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0005634(nucleus);GO:0005515(protein binding);GO:0070062(extracellular exosome);GO:0006351(transcription, DNA-templated);GO:0033613(activating transcription factor binding);GO:0042393(histone binding);GO:0043486(histone exchange)","05169(Epstein-Barr virus infection)","K13784","NA","prothymosin, alpha [Source:HGNC Symbol;Acc:HGNC:9623]",{"v":17.531918,"d":"17.53"},{"v":121.94593,"d":"121.95"},{"v":0.143767963391644,"d":"0.14"},{"v":-2.79818586699084,"d":"-2.80"},{"v":8.47295831894496e-05,"d":"0.00"},{"v":0.0021774521455945,"d":"0.00"},"down","yes"]
[19999,0,"chr10","-",45454585,45535394,"ENST00000453424",8,5638,"MSTRG.1694","MARCH8","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0016740(transferase activity);GO:0016567(protein ubiquitination);GO:0005765(lysosomal membrane);GO:0030659(cytoplasmic vesicle membrane);GO:0031410(cytoplasmic vesicle);GO:0002376(immune system process);GO:0005764(lysosome);GO:0002250(adaptive immune response);GO:0005768(endosome);GO:0031901(early endosome membrane);GO:0004842(ubiquitin-protein transferase activity);GO:0000209(protein polyubiquitination)","NA","NA","NA","membrane associated ring-CH-type finger 8 [Source:HGNC Symbol;Acc:HGNC:23356]",{"v":9.485863,"d":"9.49"},{"v":1.46957,"d":"1.47"},{"v":6.45485618242071,"d":"6.45"},{"v":2.6903849518888,"d":"2.69"},{"v":8.49667371435519E-5,"d":"0.00"},{"v":0.00218074011218823,"d":"0.00"},"up","yes"]
[60032,0,"chr15","+",24954935,24978583,"ENST00000346403",10,1304,"MSTRG.4908","SNRPN","GO:0003723(RNA binding);GO:0008380(RNA splicing);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0019013(viral nucleocapsid);GO:0030529(intracellular ribonucleoprotein complex);GO:0005681(spliceosomal complex);GO:0005737(cytoplasm);GO:0005515(protein binding);GO:0000398(mRNA splicing, via spliceosome);GO:0005682(U5 snRNP);GO:0046540(U4/U6 x U5 tri-snRNP complex);GO:0071013(catalytic step 2 spliceosome);GO:0005686(U2 snRNP);GO:0005685(U1 snRNP);GO:0071004(U2-type prespliceosome);GO:0030532(small nuclear ribonucleoprotein complex);GO:0009725(response to hormone);GO:0005687(U4 snRNP)","NA","NA","NA","small nuclear ribonucleoprotein polypeptide N [Source:HGNC Symbol;Acc:HGNC:11164]",{"v":12.597475,"d":"12.60"},{"v":1.917183,"d":"1.92"},{"v":6.57082552891404,"d":"6.57"},{"v":2.71607463563926,"d":"2.72"},{"v":8.5207288163993e-05,"d":"0.00"},{"v":0.0021841067138108,"d":"0.00"},"up","yes"]
[69649,0,"chr16","-",11547722,11587563,"ENST00000571688",4,2632,"MSTRG.5646","LITAF","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0043231(intracellular membrane-bounded organelle);GO:0046872(metal ion binding);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0006366(transcription from RNA polymerase II promoter);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0005794(Golgi apparatus);GO:0005765(lysosomal membrane);GO:0008270(zinc ion binding);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0004871(signal transducer activity);GO:0000139(Golgi membrane);GO:0007165(signal transduction);GO:0005764(lysosome);GO:0005768(endosome);GO:0031902(late endosome membrane);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0010008(endosome membrane);GO:0031901(early endosome membrane);GO:0043123(positive regulation of I-kappaB kinase/NF-kappaB signaling);GO:0009898(cytoplasmic side of plasma membrane);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0001077(transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0098559(cytoplasmic side of early endosome membrane);GO:0050699(WW domain binding);GO:0098574(cytoplasmic side of lysosomal membrane);GO:0001817(regulation of cytokine production);GO:0007568(aging);GO:0032496(response to lipopolysaccharide);GO:0042347(negative regulation of NF-kappaB import into nucleus);GO:0071222(cellular response to lipopolysaccharide);GO:0098560(cytoplasmic side of late endosome membrane);GO:0016021(integral component of membrane)","04142(Lysosome)","NA","NA","lipopolysaccharide induced TNF factor [Source:HGNC Symbol;Acc:HGNC:16841]",{"v":24.786825,"d":"24.79"},{"v":3.854748,"d":"3.85"},{"v":6.43020633255404,"d":"6.43"},{"v":2.68486503151536,"d":"2.68"},{"v":8.68515302348424e-05,"d":"0.00"},{"v":0.00222339917401197,"d":"0.00"},"up","yes"]
[60762,0,"chr15","-",34233259,34337786,"ENST00000559664",25,5111,"MSTRG.4885","SLC12A6","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005215(transporter activity);GO:0055085(transmembrane transport);GO:0006811(ion transport);GO:0005887(integral component of plasma membrane);GO:0015293(symporter activity);GO:0006813(potassium ion transport);GO:0005886(plasma membrane);GO:0071805(potassium ion transmembrane transport);GO:0015377(cation:chloride symporter activity);GO:0015379(potassium:chloride symporter activity);GO:0071477(cellular hypotonic salinity response);GO:1902476(chloride transmembrane transport);GO:0022820(potassium ion symporter activity);GO:0016323(basolateral plasma membrane);GO:0007268(chemical synaptic transmission);GO:0001525(angiogenesis)","NA","NA","NA","solute carrier family 12 member 6 [Source:HGNC Symbol;Acc:HGNC:10914]",{"v":0.156351,"d":"0.16"},{"v":1.165636,"d":"1.17"},{"v":0.134133640347415,"d":"0.13"},{"v":-2.89825698832402,"d":"-2.90"},{"v":8.78315271962391e-05,"d":"0.00"},{"v":0.00224560811146543,"d":"0.00"},"down","yes"]
[87687,0,"chr17","-",74609887,74623738,"ENST00000392619",4,3501,"MSTRG.7179","CD300E","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005886(plasma membrane);GO:0002376(immune system process);GO:0050776(regulation of immune response);GO:0070062(extracellular exosome);GO:0045087(innate immune response)","NA","NA","NA","CD300e molecule [Source:HGNC Symbol;Acc:HGNC:28874]",{"v":15.460776,"d":"15.46"},{"v":2.409051,"d":"2.41"},{"v":6.4177869210739,"d":"6.42"},{"v":2.68207589105115,"d":"2.68"},{"v":8.84443670274832e-05,"d":"0.00"},{"v":0.00225838506496776,"d":"0.00"},"up","yes"]
[92115,0,"chr18","-",46089599,46104227,"ENST00000590406",6,756,"MSTRG.7505","ATP5A1","GO:0003723(RNA binding);GO:0006810(transport);GO:0016020(membrane);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0005743(mitochondrial inner membrane);GO:0006629(lipid metabolic process);GO:0005739(mitochondrion);GO:0015992(proton transport);GO:0006811(ion transport);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0099132(ATP hydrolysis coupled cation transmembrane transport);GO:0046933(proton-transporting ATP synthase activity, rotational mechanism);GO:0015986(ATP synthesis coupled proton transport);GO:0045261(proton-transporting ATP synthase complex, catalytic core F(1));GO:0046034(ATP metabolic process);GO:0070062(extracellular exosome);GO:0008180(COP9 signalosome);GO:0005759(mitochondrial matrix);GO:0016887(ATPase activity);GO:0031012(extracellular matrix);GO:0006754(ATP biosynthetic process);GO:0009790(embryo development);GO:0001937(negative regulation of endothelial cell proliferation);GO:0042288(MHC class I protein binding);GO:0022857(transmembrane transporter activity);GO:0042407(cristae formation);GO:0042776(mitochondrial ATP synthesis coupled proton transport);GO:0005753(mitochondrial proton-transporting ATP synthase complex);GO:0043532(angiostatin binding);GO:0043536(positive regulation of blood vessel endothelial cell migration);GO:0045259(proton-transporting ATP synthase complex);GO:0032559(adenyl ribonucleotide binding);GO:0043209(myelin sheath)","00190(Oxidative phosphorylation);05010(Alzheimer's disease);05012(Parkinson's disease);05016(Huntington's disease)","NA","NA","ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle [Source:HGNC Symbol;Acc:HGNC:823]",{"v":24.163414,"d":"24.16"},{"v":3.713948,"d":"3.71"},{"v":6.50612609546499,"d":"6.51"},{"v":2.70179878357473,"d":"2.70"},{"v":9.06904326126544E-5,"d":"0.00"},{"v":0.00231277976808363,"d":"0.00"},"up","yes"]
[66524,0,"chr15","+",90915995,90919689,"ENST00000559341",4,623,"MSTRG.5438","MAN2A2","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0046872(metal ion binding);GO:0030246(carbohydrate binding);GO:0016787(hydrolase activity);GO:0003824(catalytic activity);GO:0005975(carbohydrate metabolic process);GO:0008152(metabolic process);GO:0016798(hydrolase activity, acting on glycosyl bonds);GO:0004559(alpha-mannosidase activity);GO:0006013(mannose metabolic process);GO:0005794(Golgi apparatus);GO:0000139(Golgi membrane);GO:0006486(protein glycosylation);GO:0006517(protein deglycosylation);GO:0006491(N-glycan processing);GO:0004572(mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity);GO:0015923(mannosidase activity);GO:0016799(hydrolase activity, hydrolyzing N-glycosyl compounds)","00510(N-Glycan biosynthesis)","NA","NA","mannosidase alpha class 2A member 2 [Source:HGNC Symbol;Acc:HGNC:6825]",{"v":2.509007,"d":"2.51"},{"v":17.873844,"d":"17.87"},{"v":0.140373106087308,"d":"0.14"},{"v":-2.83266153695876,"d":"-2.83"},{"v":9.1656617540329e-05,"d":"0.00"},{"v":0.00233228022333528,"d":"0.00"},"down","yes"]
[130334,0,"chr22","+",30881681,30907623,"ENST00000431368",12,3050,"MSTRG.10375","OSBP2","GO:0006810(transport);GO:0016020(membrane);GO:0005515(protein binding);GO:0006869(lipid transport);GO:0008289(lipid binding);GO:0015485(cholesterol binding);GO:0007286(spermatid development);GO:0097440(apical dendrite)","NA","NA","NA","oxysterol binding protein 2 [Source:HGNC Symbol;Acc:HGNC:8504]",{"v":1.235585,"d":"1.24"},{"v":8.65073,"d":"8.65"},{"v":0.142830142658481,"d":"0.14"},{"v":-2.80762761919747,"d":"-2.81"},{"v":9.18700848605673e-05,"d":"0.00"},{"v":0.00233228022333528,"d":"0.00"},"down","yes"]
[25743,0,"chr11","-",4598672,4608259,"ENST00000300747",7,3352,"ENSG00000167333","TRIM68","GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0005622(intracellular);GO:0005794(Golgi apparatus);GO:0005634(nucleus);GO:0005730(nucleolus);GO:0005829(cytosol);GO:0005737(cytoplasm);GO:0016740(transferase activity);GO:0016567(protein ubiquitination);GO:0048471(perinuclear region of cytoplasm);GO:0004842(ubiquitin-protein transferase activity);GO:0060333(interferon-gamma-mediated signaling pathway);GO:0050681(androgen receptor binding);GO:0051865(protein autoubiquitination);GO:0035035(histone acetyltransferase binding);GO:0060765(regulation of androgen receptor signaling pathway)","NA","NA","NA","tripartite motif containing 68 [Source:HGNC Symbol;Acc:HGNC:21161]",{"v":2.238276,"d":"2.24"},{"v":0.334995,"d":"0.33"},{"v":6.68152061971074,"d":"6.68"},{"v":2.74017647707941,"d":"2.74"},{"v":9.191071790878e-05,"d":"0.00"},{"v":0.00233228022333528,"d":"0.00"},"up","yes"]
[163901,"j","chr6","+",29887950,29945882,"MSTRG.12803.2",7,1716,"MSTRG.12803","HLA-A","NA","NA","NA","NA","NA",{"v":120.562767,"d":"120.56"},{"v":18.983616,"d":"18.98"},{"v":6.35088525810889,"d":"6.35"},{"v":2.66695770502924,"d":"2.67"},{"v":9.19223024721989e-05,"d":"0.00"},{"v":0.00233228022333528,"d":"0.00"},"up","yes"]
[94621,0,"chr19","+",2272524,2273331,"ENST00000589739",2,657,"MSTRG.7648","OAZ1","GO:0005829(cytosol);GO:0008073(ornithine decarboxylase inhibitor activity);GO:0006595(polyamine metabolic process);GO:0043086(negative regulation of catalytic activity);GO:0006810(transport);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005515(protein binding);GO:0006521(regulation of cellular amino acid metabolic process);GO:0006596(polyamine biosynthetic process);GO:0090316(positive regulation of intracellular protein transport);GO:0045732(positive regulation of protein catabolic process);GO:1902268(negative regulation of polyamine transmembrane transport)","NA","NA","NA","ornithine decarboxylase antizyme 1 [Source:HGNC Symbol;Acc:HGNC:8095]",{"v":33.566097,"d":"33.57"},{"v":5.202387,"d":"5.20"},{"v":6.45205691156771,"d":"6.45"},{"v":2.68975916410955,"d":"2.69"},{"v":9.217094996856e-05,"d":"0.00"},{"v":0.00233562122966016,"d":"0.00"},"up","yes"]
[30277,0,"chr11","-",62676613,62679081,"ENST00000534176",10,943,"MSTRG.2470","UBXN1","GO:0005737(cytoplasm);GO:0005515(protein binding);GO:0000502(proteasome complex);GO:0005634(nucleus);GO:0030425(dendrite);GO:0043025(neuronal cell body);GO:0005783(endoplasmic reticulum);GO:0005829(cytosol);GO:0006457(protein folding);GO:0032435(negative regulation of proteasomal ubiquitin-dependent protein catabolic process);GO:0043161(proteasome-mediated ubiquitin-dependent protein catabolic process);GO:0031397(negative regulation of protein ubiquitination);GO:0031625(ubiquitin protein ligase binding);GO:0051117(ATPase binding);GO:0043130(ubiquitin binding);GO:0034098(VCP-NPL4-UFD1 AAA ATPase complex);GO:0031593(polyubiquitin binding);GO:0036435(K48-linked polyubiquitin binding);GO:0071796(K6-linked polyubiquitin binding);GO:1903094(negative regulation of protein K48-linked deubiquitination);GO:1904293(negative regulation of ERAD pathway);GO:2000157(negative regulation of ubiquitin-specific protease activity)","NA","NA","NA","UBX domain protein 1 [Source:HGNC Symbol;Acc:HGNC:18402]",{"v":0.747329,"d":"0.75"},{"v":5.581662,"d":"5.58"},{"v":0.133890049236231,"d":"0.13"},{"v":-2.90087935193237,"d":"-2.90"},{"v":9.23400091836111e-05,"d":"0.00"},{"v":0.00233693954800804,"d":"0.00"},"down","yes"]
[189770,0,"chr9","+",34179005,34251850,"ENST00000625521",6,2029,"MSTRG.14732","UBAP1","GO:0006810(transport);GO:0005737(cytoplasm);GO:0015031(protein transport);GO:0005794(Golgi apparatus);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0005768(endosome);GO:0016197(endosomal transport);GO:0019058(viral life cycle);GO:0075733(intracellular transport of virus);GO:0000813(ESCRT I complex);GO:0010008(endosome membrane);GO:0043657(host cell);GO:0043130(ubiquitin binding);GO:0043162(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)","NA","NA","NA","ubiquitin associated protein 1 [Source:HGNC Symbol;Acc:HGNC:12461]",{"v":1.662109,"d":"1.66"},{"v":11.629901,"d":"11.63"},{"v":0.142916865758359,"d":"0.14"},{"v":-2.80675191456169,"d":"-2.81"},{"v":9.24570792053416e-05,"d":"0.00"},{"v":2.33694045262311E-3,"d":"0.00"},"down","yes"]
[179211,0,"chr7","+",139375204,139423201,"ENST00000498518",9,2837,"MSTRG.14004","LUC7L2","GO:0003723(RNA binding);GO:0003729(mRNA binding);GO:0005634(nucleus);GO:0016607(nuclear speck);GO:0005515(protein binding);GO:0005654(nucleoplasm);GO:0005685(U1 snRNP);GO:0006376(mRNA splice site selection);GO:0019899(enzyme binding);GO:0071004(U2-type prespliceosome)","NA","NA","NA","LUC7 like 2, pre-mRNA splicing factor [Source:HGNC Symbol;Acc:HGNC:21608]",{"v":3.134233,"d":"3.13"},{"v":0.470398,"d":"0.47"},{"v":6.6629386179363,"d":"6.66"},{"v":2.73615860289514,"d":"2.74"},{"v":9.36372851564135e-05,"d":"0.00"},{"v":2.36377915297505E-3,"d":"0.00"},"up","yes"]
[119066,"j","chr2","+",218382229,218395343,"MSTRG.9417.7",15,2891,"MSTRG.9417","SLC11A1","NA","NA","NA","NA","NA",{"v":2.297725,"d":"2.30"},{"v":15.875778,"d":"15.88"},{"v":0.144731489694552,"d":"0.14"},{"v":-2.78854924707693,"d":"-2.79"},{"v":9.38795720731984e-05,"d":"0.00"},{"v":0.00236690315045155,"d":"0.00"},"down","yes"]
[160146,0,"chr5","-",151030581,151081074,"ENST00000518977",18,2200,"MSTRG.12464","TNIP1","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0005515(protein binding);GO:0002755(MyD88-dependent toll-like receptor signaling pathway);GO:0006954(inflammatory response);GO:0042802(identical protein binding);GO:0050727(regulation of inflammatory response);GO:0043124(negative regulation of I-kappaB kinase/NF-kappaB signaling);GO:0070373(negative regulation of ERK1 and ERK2 cascade);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0005622(intracellular);GO:0016579(protein deubiquitination);GO:0045071(negative regulation of viral genome replication);GO:0050729(positive regulation of inflammatory response);GO:0006412(translation);GO:0006952(defense response);GO:0051019(mitogen-activated protein kinase binding);GO:0009101(glycoprotein biosynthetic process);GO:0007159(leukocyte cell-cell adhesion);GO:0031593(polyubiquitin binding);GO:0071222(cellular response to lipopolysaccharide);GO:0085032(modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade);GO:1903003(positive regulation of protein deubiquitination)","NA","NA","NA","TNFAIP3 interacting protein 1 [Source:HGNC Symbol;Acc:HGNC:16903]",{"v":1.929082,"d":"1.93"},{"v":13.424978,"d":"13.42"},{"v":0.14369349432081,"d":"0.14"},{"v":-2.79893334919211,"d":"-2.80"},{"v":9.45350908385292e-05,"d":"0.00"},{"v":0.00238042458242592,"d":"0.00"},"down","yes"]
[24716,"i","chr11","-",309055,309422,"MSTRG.2063.1",2,300,"MSTRG.2063","IFITM2","NA","NA","NA","NA","NA",{"v":52.142761,"d":"52.14"},{"v":8.053926,"d":"8.05"},{"v":6.4742041334872,"d":"6.47"},{"v":2.69470285484686,"d":"2.69"},{"v":9.51927176329406E-5,"d":"0.00"},{"v":0.0023922536883411,"d":"0.00"},"up","yes"]
[36939,"j","chr11","+",130069886,130144806,"MSTRG.2988.3",17,3574,"MSTRG.2988","APLP2","NA","NA","NA","NA","NA",{"v":1.109911,"d":"1.11"},{"v":7.708855,"d":"7.71"},{"v":0.143978710197559,"d":"0.14"},{"v":-2.79607259546385,"d":"-2.80"},{"v":9.5244475271994E-5,"d":"0.00"},{"v":0.0023922536883411,"d":"0.00"},"down","yes"]
[121462,0,"chr20","-",1443735,1466824,"ENST00000381653",9,1446,"MSTRG.9549","NSFL1C","GO:0005634(nucleus);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0005794(Golgi apparatus);GO:0005886(plasma membrane);GO:0005694(chromosome);GO:0045111(intermediate filament cytoskeleton);GO:0050790(regulation of catalytic activity);GO:0005515(protein binding);GO:0008289(lipid binding);GO:0043161(proteasome-mediated ubiquitin-dependent protein catabolic process);GO:0000045(autophagosome assembly);GO:0007030(Golgi organization);GO:0043130(ubiquitin binding);GO:0005795(Golgi stack);GO:0061025(membrane fusion);GO:1990730(VCP-NSFL1C complex);GO:0019888(protein phosphatase regulator activity);GO:0031468(nuclear envelope reassembly);GO:0005543(phospholipid binding);GO:0051117(ATPase binding)","04141(Protein processing in endoplasmic reticulum)","K14012","NA","NSFL1 cofactor [Source:HGNC Symbol;Acc:HGNC:15912]",{"v":5.971278,"d":"5.97"},{"v":0.900684,"d":"0.90"},{"v":6.62971475012324,"d":"6.63"},{"v":2.72894679832645,"d":"2.73"},{"v":9.58488306630707e-05,"d":"0.00"},{"v":0.00240440885763844,"d":"0.00"},"up","yes"]
[154361,0,"chr5","-",38940020,39074399,"ENST00000296782",39,7505,"MSTRG.12010","RICTOR","GO:0043085(positive regulation of catalytic activity);GO:0005515(protein binding);GO:0007275(multicellular organism development);GO:0031932(TORC2 complex);GO:0005829(cytosol);GO:0032956(regulation of actin cytoskeleton organization);GO:0031929(TOR signaling);GO:0038111(interleukin-7-mediated signaling pathway);GO:0048015(phosphatidylinositol-mediated signaling);GO:0009790(embryo development);GO:0032008(positive regulation of TOR signaling);GO:0031532(actin cytoskeleton reorganization);GO:0031295(T cell costimulation);GO:0019901(protein kinase binding);GO:0018105(peptidyl-serine phosphorylation);GO:0008047(enzyme activator activity);GO:0051896(regulation of protein kinase B signaling);GO:0030010(establishment of cell polarity);GO:0030950(establishment or maintenance of actin cytoskeleton polarity);GO:0042325(regulation of phosphorylation);GO:0051897(positive regulation of protein kinase B signaling);GO:0043022(ribosome binding);GO:0001932(regulation of protein phosphorylation);GO:0001938(positive regulation of endothelial cell proliferation);GO:0010468(regulation of gene expression);GO:0030838(positive regulation of actin filament polymerization);GO:0033135(regulation of peptidyl-serine phosphorylation);GO:0043087(regulation of GTPase activity);GO:0050727(regulation of inflammatory response);GO:0050731(positive regulation of peptidyl-tyrosine phosphorylation);GO:2000114(regulation of establishment of cell polarity)","04150(mTOR signaling pathway)","K08267","NA","RPTOR independent companion of MTOR complex 2 [Source:HGNC Symbol;Acc:HGNC:28611]",{"v":0.534826,"d":"0.53"},{"v":3.707234,"d":"3.71"},{"v":0.144265509002129,"d":"0.14"},{"v":-2.7932016733633,"d":"-2.79"},{"v":9.66273955732309e-05,"d":"0.00"},{"v":0.0024208981616139,"d":"0.00"},"down","yes"]
[196593,0,"chrX","+",41688973,41697277,"ENST00000378142",3,1928,"ENSG00000171659","GPR34","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0004930(G-protein coupled receptor activity);GO:0007186(G-protein coupled receptor signaling pathway);GO:0005886(plasma membrane);GO:0004871(signal transducer activity);GO:0007165(signal transduction);GO:0035589(G-protein coupled purinergic nucleotide receptor signaling pathway);GO:0005887(integral component of plasma membrane);GO:0045028(G-protein coupled purinergic nucleotide receptor activity)","NA","NA","NA","G protein-coupled receptor 34 [Source:HGNC Symbol;Acc:HGNC:4490]",{"v":0.362265,"d":"0.36"},{"v":2.710139,"d":"2.71"},{"v":0.133670265621062,"d":"0.13"},{"v":-2.90324951510966,"d":"-2.90"},{"v":9.7385113103988e-05,"d":"0.00"},{"v":0.00243682448428626,"d":"0.00"},"down","yes"]
[74539,0,"chr16","+",67645247,67657518,"ENST00000545661",38,4119,"MSTRG.6032","CARMIL2","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005886(plasma membrane);GO:0005856(cytoskeleton);GO:0042995(cell projection);GO:0016477(cell migration);GO:0031234(extrinsic component of cytoplasmic side of plasma membrane);GO:0030027(lamellipodium);GO:0031252(cell leading edge);GO:0030335(positive regulation of cell migration);GO:0001726(ruffle);GO:0005543(phospholipid binding);GO:0032403(protein complex binding);GO:0044319(wound healing, spreading of cells);GO:0015629(actin cytoskeleton);GO:0010592(positive regulation of lamellipodium assembly);GO:0007163(establishment or maintenance of cell polarity);GO:0090091(positive regulation of extracellular matrix disassembly);GO:1900029(positive regulation of ruffle assembly);GO:0051639(actin filament network formation);GO:0045111(intermediate filament cytoskeleton);GO:0044354(macropinosome);GO:1902745(positive regulation of lamellipodium organization);GO:2000813(negative regulation of barbed-end actin filament capping);GO:0030011(maintenance of cell polarity);GO:0061339(establishment or maintenance of monopolar cell polarity)","NA","NA","NA","capping protein regulator and myosin 1 linker 2 [Source:HGNC Symbol;Acc:HGNC:27089]",{"v":3.690978,"d":"3.69"},{"v":0.572317,"d":"0.57"},{"v":6.4491846301962,"d":"6.45"},{"v":2.68911677226753,"d":"2.69"},{"v":9.75585515799425e-05,"d":"0.00"},{"v":0.0024381090837901,"d":"0.00"},"up","yes"]
[136225,0,"chr3","+",49171611,49176486,"ENST00000332780",6,1959,"ENSG00000185909","KLHDC8B","GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0016567(protein ubiquitination);GO:0004842(ubiquitin-protein transferase activity);GO:0031463(Cul3-RING ubiquitin ligase complex)","NA","NA","NA","kelch domain containing 8B [Source:HGNC Symbol;Acc:HGNC:28557]",{"v":0.361397,"d":"0.36"},{"v":2.702771,"d":"2.70"},{"v":0.133713511059576,"d":"0.13"},{"v":-2.90278284520917,"d":"-2.90"},{"v":9.83396084752984e-05,"d":"0.00"},{"v":2.45455662754345E-3,"d":"0.00"},"down","yes"]
[55897,0,"chr14","-",64746283,64879883,"ENST00000556626",36,10153,"MSTRG.4477","SPTB","GO:0005737(cytoplasm);GO:0005794(Golgi apparatus);GO:0005829(cytosol);GO:0003779(actin binding);GO:0051693(actin filament capping);GO:0043547(positive regulation of GTPase activity);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0005200(structural constituent of cytoskeleton);GO:0007010(cytoskeleton organization);GO:0008091(spectrin);GO:0051015(actin filament binding);GO:0005938(cell cortex);GO:0000165(MAPK cascade);GO:0043234(protein complex);GO:0015629(actin cytoskeleton);GO:0007411(axon guidance);GO:0006888(ER to Golgi vesicle-mediated transport);GO:0005088(Ras guanyl-nucleotide exchange factor activity);GO:0030506(ankyrin binding);GO:0014731(spectrin-associated cytoskeleton);GO:0031235(intrinsic component of the cytoplasmic side of the plasma membrane)","NA","NA","NA","spectrin beta, erythrocytic [Source:HGNC Symbol;Acc:HGNC:11274]",{"v":0.387634,"d":"0.39"},{"v":2.685949,"d":"2.69"},{"v":0.1443191959341,"d":"0.14"},{"v":-2.79266488904949,"d":"-2.79"},{"v":9.88656915376274e-05,"d":"0.00"},{"v":0.00246140893821032,"d":"0.00"},"down","yes"]
[111387,0,"chr2","+",74555132,74557513,"ENST00000464613",4,1807,"MSTRG.8845","DOK1","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005515(protein binding);GO:0048471(perinuclear region of cytoplasm);GO:0005158(insulin receptor binding);GO:0007165(signal transduction);GO:0007166(cell surface receptor signaling pathway);GO:0007411(axon guidance);GO:0007169(transmembrane receptor protein tyrosine kinase signaling pathway);GO:0045742(positive regulation of epidermal growth factor receptor signaling pathway);GO:0005057(signal transducer activity, downstream of receptor);GO:0007265(Ras protein signal transduction);GO:0035556(intracellular signal transduction)","05162(Measles)","NA","NA","docking protein 1 [Source:HGNC Symbol;Acc:HGNC:2990]",{"v":2.69524,"d":"2.70"},{"v":0.39495,"d":"0.39"},{"v":6.82425623496645,"d":"6.82"},{"v":2.7706718175201,"d":"2.77"},{"v":9.8981134411914e-05,"d":"0.00"},{"v":0.00246140893821032,"d":"0.00"},"up","yes"]
[59502,"j","chr14","-",105707111,105863978,"MSTRG.4749.15",4,1283,"MSTRG.4749","IGHA1","NA","NA","NA","NA","NA",{"v":542.012756,"d":"542.01"},{"v":86.274422,"d":"86.27"},{"v":6.28242697470636,"d":"6.28"},{"v":2.65132199669228,"d":"2.65"},{"v":9.89839431782294e-05,"d":"0.00"},{"v":0.00246140893821032,"d":"0.00"},"up","yes"]
[152445,0,"chr4","+",176319964,176332245,"ENST00000503362",5,4571,"MSTRG.11926","SPCS3","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016787(hydrolase activity);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0008233(peptidase activity);GO:0006508(proteolysis);GO:0006465(signal peptide processing);GO:0005787(signal peptidase complex);GO:0043231(intracellular membrane-bounded organelle);GO:0031090(organelle membrane);GO:0045047(protein targeting to ER)","03060(Protein export)","K12948","EC:3.4.-.-","signal peptidase complex subunit 3 [Source:HGNC Symbol;Acc:HGNC:26212]",{"v":1.245981,"d":"1.25"},{"v":8.574585,"d":"8.57"},{"v":0.145310939246622,"d":"0.15"},{"v":-2.78278477937159,"d":"-2.78"},{"v":9.92038390912199e-05,"d":"0.00"},{"v":0.00246380877981776,"d":"0.00"},"down","yes"]
[70296,0,"chr16","-",19501689,19522145,"ENST00000353258",6,2958,"MSTRG.5712","GDE1","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0046872(metal ion binding);GO:0016787(hydrolase activity);GO:0006629(lipid metabolic process);GO:0005886(plasma membrane);GO:0030659(cytoplasmic vesicle membrane);GO:0031410(cytoplasmic vesicle);GO:0008081(phosphoric diester hydrolase activity);GO:0008889(glycerophosphodiester phosphodiesterase activity);GO:0046475(glycerophospholipid catabolic process);GO:0004622(lysophospholipase activity);GO:0047395(glycerophosphoinositol glycerophosphodiesterase activity);GO:0006644(phospholipid metabolic process);GO:0070291(N-acylethanolamine metabolic process)","NA","NA","NA","glycerophosphodiester phosphodiesterase 1 [Source:HGNC Symbol;Acc:HGNC:29644]",{"v":2.231095,"d":"2.23"},{"v":15.317697,"d":"15.32"},{"v":0.145654728644913,"d":"0.15"},{"v":-2.77937555590942,"d":"-2.78"},{"v":9.95245131314853e-05,"d":"0.00"},{"v":0.0024687024574031,"d":"0.00"},"down","yes"]
[5719,0,"chr1","-",46607725,46616465,"ENST00000371940",3,5725,"MSTRG.540","MOB3C","GO:0046872(metal ion binding);GO:0005515(protein binding)","NA","NA","NA","MOB kinase activator 3C [Source:HGNC Symbol;Acc:HGNC:29800]",{"v":0.205399,"d":"0.21"},{"v":1.473938,"d":"1.47"},{"v":0.139353894125804,"d":"0.14"},{"v":-2.84317477699899,"d":"-2.84"},{"v":9.97384206966859e-05,"d":"0.00"},{"v":0.00247093893855015,"d":"0.00"},"down","yes"]
[177592,0,"chr7","-",106277056,106285612,"ENST00000417537",3,300,"MSTRG.13893","NAMPT","GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016607(nuclear speck);GO:0016740(transferase activity);GO:0016757(transferase activity, transferring glycosyl groups);GO:0030054(cell junction);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0048511(rhythmic process);GO:0005125(cytokine activity);GO:0005615(extracellular space);GO:0009435(NAD biosynthetic process);GO:0019363(pyridine nucleotide biosynthetic process);GO:0004514(nicotinate-nucleotide diphosphorylase (carboxylating) activity);GO:0008144(drug binding);GO:0042803(protein homodimerization activity);GO:0047280(nicotinamide phosphoribosyltransferase activity);GO:0007565(female pregnancy);GO:0007623(circadian rhythm);GO:0014070(response to organic cyclic compound);GO:0032922(circadian regulation of gene expression);GO:0048661(positive regulation of smooth muscle cell proliferation);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0007165(signal transduction);GO:0007267(cell-cell signaling);GO:0051770(positive regulation of nitric-oxide synthase biosynthetic process);GO:0008284(positive regulation of cell proliferation);GO:0034356(NAD biosynthesis via nicotinamide riboside salvage pathway)","00760(Nicotinate and nicotinamide metabolism);04621(NOD-like receptor signaling pathway)","NA","NA","nicotinamide phosphoribosyltransferase [Source:HGNC Symbol;Acc:HGNC:30092]",{"v":6.318089,"d":"6.32"},{"v":44.21196,"d":"44.21"},{"v":0.14290452176289,"d":"0.14"},{"v":-2.8068765281969,"d":"-2.81"},{"v":1.01044196866818E-4,"d":"0.00"},{"v":0.00250018652173064,"d":"0.00"},"down","yes"]
[152275,0,"chr4","-",173331701,173334391,"ENST00000446922",5,1175,"MSTRG.11912","HMGB2","GO:0005634(nucleus);GO:0003723(RNA binding);GO:0005737(cytoplasm);GO:0005730(nucleolus);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0005623(cell);GO:0006334(nucleosome assembly);GO:0005694(chromosome);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0006310(DNA recombination);GO:0048471(perinuclear region of cytoplasm);GO:0005615(extracellular space);GO:0008134(transcription factor binding);GO:0045893(positive regulation of transcription, DNA-templated);GO:0002376(immune system process);GO:0045087(innate immune response);GO:0006935(chemotaxis);GO:0006954(inflammatory response);GO:0000400(four-way junction DNA binding);GO:0097100(supercoiled DNA binding);GO:0032392(DNA geometric change);GO:0050918(positive chemotaxis);GO:0006325(chromatin organization);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0005654(nucleoplasm);GO:0071222(cellular response to lipopolysaccharide);GO:0043234(protein complex);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0003690(double-stranded DNA binding);GO:0001158(enhancer sequence-specific DNA binding);GO:0000790(nuclear chromatin);GO:0044212(transcription regulatory region DNA binding);GO:0006309(apoptotic DNA fragmentation);GO:0045892(negative regulation of transcription, DNA-templated);GO:0060326(cell chemotaxis);GO:0003697(single-stranded DNA binding);GO:0008301(DNA binding, bending);GO:0042056(chemoattractant activity);GO:0003684(damaged DNA binding);GO:0001938(positive regulation of endothelial cell proliferation);GO:0000793(condensed chromosome);GO:0043388(positive regulation of DNA binding);GO:0050786(RAGE receptor binding);GO:0006265(DNA topological change);GO:0033151(V(D)J recombination);GO:0051103(DNA ligation involved in DNA repair);GO:0045648(positive regulation of erythrocyte differentiation);GO:0045654(positive regulation of megakaryocyte differentiation);GO:0008144(drug binding);GO:0019904(protein domain specific binding);GO:0044378(non-sequence-specific DNA binding, bending);GO:0002437(inflammatory response to antigenic stimulus);GO:0007283(spermatogenesis);GO:0007289(spermatid nucleus differentiation);GO:0008584(male gonad development);GO:0010628(positive regulation of gene expression);GO:0010629(negative regulation of gene expression);GO:0032075(positive regulation of nuclease activity);GO:0032496(response to lipopolysaccharide);GO:0032728(positive regulation of interferon-beta production);GO:0042493(response to drug);GO:0045089(positive regulation of innate immune response);GO:0048545(response to steroid hormone);GO:0050767(regulation of neurogenesis);GO:0050829(defense response to Gram-negative bacterium);GO:0050830(defense response to Gram-positive bacterium);GO:0072091(regulation of stem cell proliferation);GO:1902042(negative regulation of extrinsic apoptotic signaling pathway via death domain receptors)","NA","NA","NA","high mobility group box 2 [Source:HGNC Symbol;Acc:HGNC:5000]",{"v":18.335192,"d":"18.34"},{"v":2.877784,"d":"2.88"},{"v":6.3712884636234,"d":"6.37"},{"v":2.67158515774199,"d":"2.67"},{"v":1.01511625714137E-4,"d":"0.00"},{"v":0.00250615962325912,"d":"0.00"},"up","yes"]
[118031,"j","chr2","+",201260538,201287495,"MSTRG.9357.20",7,2333,"MSTRG.9357","CASP8","NA","NA","NA","NA","NA",{"v":4.556897,"d":"4.56"},{"v":31.093769,"d":"31.09"},{"v":0.146553381804567,"d":"0.15"},{"v":-2.7705018354482,"d":"-2.77"},{"v":0.000101536615345384,"d":"0.00"},{"v":0.00250615962325912,"d":"0.00"},"down","yes"]
[71425,0,"chr16","+",28974804,28990775,"ENST00000569969",19,5296,"MSTRG.5787","AC109460.3","NA","NA","NA","NA","NA",{"v":6.052235,"d":"6.05"},{"v":0.954615,"d":"0.95"},{"v":6.33997475422029,"d":"6.34"},{"v":2.66447709556441,"d":"2.66"},{"v":1.01773675711999E-4,"d":"0.00"},{"v":0.0025089095760706,"d":"0.00"},"up","yes"]
[82242,0,"chr17","-",35473689,35487857,"ENST00000260908",4,3119,"MSTRG.6701","SLFN12L","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005524(ATP binding)","NA","NA","NA","schlafen family member 12 like [Source:HGNC Symbol;Acc:HGNC:33920]",{"v":1.451623,"d":"1.45"},{"v":0.212777,"d":"0.21"},{"v":6.82227402397816,"d":"6.82"},{"v":2.77025270351402,"d":"2.77"},{"v":1.02591609953184E-4,"d":"0.00"},{"v":0.00252595470720738,"d":"0.00"},"up","yes"]
[194607,"p","chr9","-",134902122,134905861,"MSTRG.15084.1",1,3740,"MSTRG.15084","FCN1","NA","NA","NA","NA","NA",{"v":1.582985,"d":"1.58"},{"v":0.23546,"d":"0.24"},{"v":6.72294657266627,"d":"6.72"},{"v":2.74909368450094,"d":"2.75"},{"v":1.02917354219502E-4,"d":"0.00"},{"v":0.00253085434612688,"d":"0.00"},"up","yes"]
[31997,0,"chr11","-",67440791,67443472,"ENST00000453768",6,1161,"MSTRG.2613","CORO1B","GO:0005737(cytoplasm);GO:0003779(actin binding);GO:0005829(cytosol);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0048471(perinuclear region of cytoplasm);GO:0005925(focal adhesion);GO:0045296(cadherin binding);GO:0051015(actin filament binding);GO:0030027(lamellipodium);GO:0031252(cell leading edge);GO:0070062(extracellular exosome);GO:0071944(cell periphery);GO:0001725(stress fiber);GO:0042802(identical protein binding);GO:0051017(actin filament bundle assembly);GO:0016477(cell migration);GO:0005884(actin filament);GO:0042060(wound healing);GO:0035767(endothelial cell chemotaxis);GO:0005886(plasma membrane);GO:0031529(ruffle organization);GO:2000394(positive regulation of lamellipodium morphogenesis);GO:0071672(negative regulation of smooth muscle cell chemotaxis);GO:0034315(regulation of Arp2/3 complex-mediated actin nucleation);GO:0036120(cellular response to platelet-derived growth factor stimulus);GO:0071933(Arp2/3 complex binding);GO:0030036(actin cytoskeleton organization);GO:0034316(negative regulation of Arp2/3 complex-mediated actin nucleation);GO:0090135(actin filament branching);GO:1902463(protein localization to cell leading edge)","NA","NA","NA","coronin 1B [Source:HGNC Symbol;Acc:HGNC:2253]",{"v":5.027262,"d":"5.03"},{"v":0.751567,"d":"0.75"},{"v":6.6890403649974,"d":"6.69"},{"v":2.74179925123078,"d":"2.74"},{"v":1.03696106217403E-4,"d":"0.00"},{"v":2.54686820288941E-3,"d":"0.00"},"up","yes"]
[38590,0,"chr12","+",8914741,8939935,"ENST00000544916",15,3626,"MSTRG.3140","PHC1","GO:0005634(nucleus);GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0007275(multicellular organism development);GO:0005654(nucleoplasm);GO:0031519(PcG protein complex);GO:0035102(PRC1 complex);GO:0016574(histone ubiquitination)","NA","NA","NA","polyhomeotic homolog 1 [Source:HGNC Symbol;Acc:HGNC:3182]",{"v":0.218746,"d":"0.22"},{"v":1.580094,"d":"1.58"},{"v":0.138438599222578,"d":"0.14"},{"v":-2.85268184596614,"d":"-2.85"},{"v":0.000105377144855711,"d":"0.00"},{"v":0.0025849764477627,"d":"0.00"},"down","yes"]
[186720,0,"chr8","+",119416306,119424353,"ENST00000259526",5,2522,"MSTRG.14524","NOV","GO:0005737(cytoplasm);GO:0043231(intracellular membrane-bounded organelle);GO:0008083(growth factor activity);GO:0005576(extracellular region);GO:0005520(insulin-like growth factor binding);GO:0001558(regulation of cell growth);GO:0005921(gap junction);GO:0030054(cell junction);GO:0002062(chondrocyte differentiation);GO:0010468(regulation of gene expression);GO:0044342(type B pancreatic cell proliferation);GO:0046676(negative regulation of insulin secretion);GO:0048659(smooth muscle cell proliferation);GO:0050728(negative regulation of inflammatory response);GO:0060392(negative regulation of SMAD protein import into nucleus);GO:1904057(negative regulation of sensory perception of pain);GO:1990523(bone regeneration);GO:0005615(extracellular space);GO:0030424(axon);GO:0030425(dendrite);GO:0031012(extracellular matrix);GO:0043025(neuronal cell body);GO:0005515(protein binding);GO:0007267(cell-cell signaling);GO:0005578(proteinaceous extracellular matrix);GO:0030308(negative regulation of cell growth);GO:0005178(integrin binding);GO:0001525(angiogenesis);GO:0005112(Notch binding);GO:0045747(positive regulation of Notch signaling pathway);GO:0060326(cell chemotaxis);GO:0008201(heparin binding);GO:0060548(negative regulation of cell death);GO:0042347(negative regulation of NF-kappaB import into nucleus);GO:0035767(endothelial cell chemotaxis);GO:0033627(cell adhesion mediated by integrin);GO:0010832(negative regulation of myotube differentiation);GO:0071603(endothelial cell-cell adhesion);GO:0010761(fibroblast migration);GO:0014909(smooth muscle cell migration);GO:0061484(hematopoietic stem cell homeostasis);GO:0090027(negative regulation of monocyte chemotaxis);GO:1902731(negative regulation of chondrocyte proliferation)","NA","NA","NA","nephroblastoma overexpressed [Source:HGNC Symbol;Acc:HGNC:7885]",{"v":1.227443,"d":"1.23"},{"v":8.426064,"d":"8.43"},{"v":0.145672166743571,"d":"0.15"},{"v":-2.77920284368213,"d":"-2.78"},{"v":0.000105749712132633,"d":"0.00"},{"v":0.00259093282437352,"d":"0.00"},"down","yes"]
[3057,0,"chr1","-",26282284,26306645,"ENST00000374221",16,1792,"MSTRG.279","UBXN11","GO:0005737(cytoplasm);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0043161(proteasome-mediated ubiquitin-dependent protein catabolic process);GO:0043130(ubiquitin binding)","NA","NA","NA","UBX domain protein 11 [Source:HGNC Symbol;Acc:HGNC:30600]",{"v":3.459278,"d":"3.46"},{"v":0.518142,"d":"0.52"},{"v":6.67631267104384,"d":"6.68"},{"v":2.73905152186668,"d":"2.74"},{"v":1.05963022649178E-4,"d":"0.00"},{"v":2.59297749541517E-3,"d":"0.00"},"up","yes"]
[29784,0,"chr11","+",60913874,60923443,"ENST00000227525",4,2413,"MSTRG.2431","TMEM109","GO:0006810(transport);GO:0005634(nucleus);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005244(voltage-gated ion channel activity);GO:0006811(ion transport);GO:0034765(regulation of ion transmembrane transport);GO:0003674(molecular_function);GO:0070062(extracellular exosome);GO:0016529(sarcoplasmic reticulum);GO:0033017(sarcoplasmic reticulum membrane);GO:0060548(negative regulation of cell death);GO:0071480(cellular response to gamma radiation);GO:0005640(nuclear outer membrane);GO:0042771(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)","NA","NA","NA","transmembrane protein 109 [Source:HGNC Symbol;Acc:HGNC:28771]",{"v":20.645519,"d":"20.65"},{"v":3.297153,"d":"3.30"},{"v":6.26161994908941,"d":"6.26"},{"v":2.64653594632341,"d":"2.65"},{"v":1.06800867359702E-4,"d":"0.00"},{"v":0.00261028117434336,"d":"0.00"},"up","yes"]
[76699,"j","chr16","+",88570403,88631757,"MSTRG.6225.3",20,3416,"MSTRG.6225","ZC3H18","NA","NA","NA","NA","NA",{"v":5.0508,"d":"5.05"},{"v":0.797146,"d":"0.80"},{"v":6.33610405120266,"d":"6.34"},{"v":2.66359602748215,"d":"2.66"},{"v":0.000107047734363347,"d":"0.00"},{"v":0.00261311633223388,"d":"0.00"},"up","yes"]
[83041,0,"chr17","+",40062899,40092627,"ENST00000450525",9,4895,"MSTRG.6801","THRA","GO:0005634(nucleus);GO:0008270(zinc ion binding);GO:0006355(regulation of transcription, DNA-templated);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0043565(sequence-specific DNA binding);GO:0046872(metal ion binding);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0030522(intracellular receptor signaling pathway);GO:0007165(signal transduction);GO:0004887(thyroid hormone receptor activity);GO:0005829(cytosol);GO:0005515(protein binding);GO:0003707(steroid hormone receptor activity);GO:0043401(steroid hormone mediated signaling pathway);GO:0005654(nucleoplasm);GO:0006366(transcription from RNA polymerase II promoter);GO:0019904(protein domain specific binding);GO:0008134(transcription factor binding);GO:0045892(negative regulation of transcription, DNA-templated);GO:0006367(transcription initiation from RNA polymerase II promoter);GO:0044212(transcription regulatory region DNA binding);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0017055(negative regulation of RNA polymerase II transcriptional preinitiation complex assembly);GO:0070324(thyroid hormone binding);GO:0017025(TBP-class protein binding);GO:0009755(hormone-mediated signaling pathway);GO:2000143(negative regulation of DNA-templated transcription, initiation);GO:0000976(transcription regulatory region sequence-specific DNA binding);GO:0002153(steroid receptor RNA activator RNA binding);GO:0003727(single-stranded RNA binding);GO:0004879(RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding);GO:0031490(chromatin DNA binding);GO:0032403(protein complex binding);GO:0001502(cartilage condensation);GO:0001503(ossification);GO:0002155(regulation of thyroid hormone mediated signaling pathway);GO:0007611(learning or memory);GO:0008016(regulation of heart contraction);GO:0008050(female courtship behavior);GO:0009409(response to cold);GO:0009887(animal organ morphogenesis);GO:0010831(positive regulation of myotube differentiation);GO:0030218(erythrocyte differentiation);GO:0030878(thyroid gland development);GO:0033032(regulation of myeloid cell apoptotic process);GO:0042994(cytoplasmic sequestering of transcription factor);GO:0045925(positive regulation of female receptivity);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0050994(regulation of lipid catabolic process);GO:0060509(Type I pneumocyte differentiation);GO:0005737(cytoplasm)","04080(Neuroactive ligand-receptor interaction);04919(Thyroid hormone signaling pathway)","K05547","NA","thyroid hormone receptor, alpha [Source:HGNC Symbol;Acc:HGNC:11796]",{"v":3.803369,"d":"3.80"},{"v":0.600014,"d":"0.60"},{"v":6.33880042799001,"d":"6.34"},{"v":2.66420984662131,"d":"2.66"},{"v":1.07795171311238E-4,"d":"0.00"},{"v":0.00262814893863589,"d":"0.00"},"up","yes"]
[176112,0,"chr7","+",93232340,93361121,"ENST00000544910",29,5736,"ENSG00000004766","VPS50","GO:0006810(transport);GO:0016020(membrane);GO:0015031(protein transport);GO:0005768(endosome);GO:0070062(extracellular exosome);GO:0055037(recycling endosome);GO:0000149(SNARE binding);GO:0032456(endocytic recycling);GO:1990745(EARP complex)","NA","NA","NA","VPS50, EARP/GARPII complex subunit [Source:HGNC Symbol;Acc:HGNC:25956]",{"v":0.89013,"d":"0.89"},{"v":0.132911,"d":"0.13"},{"v":6.69718834407987,"d":"6.70"},{"v":2.74355554132902,"d":"2.74"},{"v":1.08273904012185E-4,"d":"0.00"},{"v":0.00263660160404306,"d":"0.00"},"up","yes"]
[58839,0,"chr14","+",102139844,102223673,"ENST00000335263",4,2616,"MSTRG.4698","WDR20","GO:0005515(protein binding);GO:0005654(nucleoplasm);GO:0016579(protein deubiquitination);GO:0036459(thiol-dependent ubiquitinyl hydrolase activity)","NA","NA","NA","WD repeat domain 20 [Source:HGNC Symbol;Acc:HGNC:19667]",{"v":0.340708,"d":"0.34"},{"v":2.454449,"d":"2.45"},{"v":0.138812417776862,"d":"0.14"},{"v":-2.84879146167035,"d":"-2.85"},{"v":1.10650351760827E-4,"d":"0.00"},{"v":0.00269118906694298,"d":"0.00"},"down","yes"]
[17730,0,"chr1","-",247297412,247331743,"ENST00000294753",9,5336,"ENSG00000162714","ZNF496","GO:0005634(nucleus);GO:0003676(nucleic acid binding);GO:0046872(metal ion binding);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0005622(intracellular);GO:0005515(protein binding);GO:0043621(protein self-association);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0045893(positive regulation of transcription, DNA-templated);GO:0016604(nuclear body);GO:0000981(RNA polymerase II transcription factor activity, sequence-specific DNA binding)","NA","NA","NA","zinc finger protein 496 [Source:HGNC Symbol;Acc:HGNC:23713]",{"v":0.231034,"d":"0.23"},{"v":1.615914,"d":"1.62"},{"v":0.142974192933535,"d":"0.14"},{"v":-2.80617333310607,"d":"-2.81"},{"v":1.13581859235057E-4,"d":"0.00"},{"v":0.00275912720827934,"d":"0.00"},"down","yes"]
[11508,0,"chr1","+",155002657,155018522,"ENST00000368426",4,3594,"MSTRG.1027","ZBTB7B","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0005654(nucleoplasm);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0007275(multicellular organism development);GO:0030154(cell differentiation);GO:0006366(transcription from RNA polymerase II promoter);GO:0007398(ectoderm development);GO:0010628(positive regulation of gene expression);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:0001077(transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0042803(protein homodimerization activity);GO:0043370(regulation of CD4-positive, alpha-beta T cell differentiation);GO:0043376(regulation of CD8-positive, alpha-beta T cell differentiation);GO:0045944(positive regulation of transcription from RNA polymerase II promoter)","NA","NA","NA","zinc finger and BTB domain containing 7B [Source:HGNC Symbol;Acc:HGNC:18668]",{"v":2.39033,"d":"2.39"},{"v":16.083622,"d":"16.08"},{"v":0.14861888696464,"d":"0.15"},{"v":-2.7503106250488,"d":"-2.75"},{"v":1.14116762658707E-4,"d":"0.00"},{"v":0.00276875275427589,"d":"0.00"},"down","yes"]
[164455,0,"chr6","+",31586179,31588909,"ENST00000438075",5,764,"MSTRG.12864","LST1","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005794(Golgi apparatus);GO:0006955(immune response);GO:0000139(Golgi membrane);GO:0002376(immune system process);GO:0000902(cell morphogenesis);GO:0012505(endomembrane system);GO:0008360(regulation of cell shape);GO:0016358(dendrite development);GO:0009653(anatomical structure morphogenesis);GO:0050672(negative regulation of lymphocyte proliferation)","NA","NA","NA","leukocyte specific transcript 1 [Source:HGNC Symbol;Acc:HGNC:14189]",{"v":1.183563,"d":"1.18"},{"v":8.45688,"d":"8.46"},{"v":0.139952677583222,"d":"0.14"},{"v":-2.83698900598237,"d":"-2.84"},{"v":1.14589430251455E-4,"d":"0.00"},{"v":2.77684677580226E-3,"d":"0.00"},"down","yes"]
[12146,0,"chr1","-",156594487,156601483,"ENST00000368232",8,1972,"MSTRG.1083","GPATCH4","GO:0003676(nucleic acid binding);GO:0002244(hematopoietic progenitor cell differentiation)","NA","NA","NA","G-patch domain containing 4 [Source:HGNC Symbol;Acc:HGNC:25982]",{"v":5.57228,"d":"5.57"},{"v":0.875321,"d":"0.88"},{"v":6.36598459308071,"d":"6.37"},{"v":2.67038366537582,"d":"2.67"},{"v":0.000115558055536697,"d":"0.00"},{"v":0.00279692515509912,"d":"0.00"},"up","yes"]
[128469,"j","chr22","-",19036283,19122445,"MSTRG.10119.3",10,4465,"MSTRG.10119","DGCR2","NA","NA","NA","NA","NA",{"v":1.837984,"d":"1.84"},{"v":12.327559,"d":"12.33"},{"v":0.149095534647208,"d":"0.15"},{"v":-2.74569104476968,"d":"-2.75"},{"v":1.16526940713501E-4,"d":"0.00"},{"v":0.00281396257101108,"d":"0.00"},"down","yes"]
[35717,0,"chr11","+",118401610,118409577,"ENST00000529790",4,900,"MSTRG.2895","ATP5L","GO:0006810(transport);GO:0016020(membrane);GO:0005739(mitochondrion);GO:0005743(mitochondrial inner membrane);GO:0006811(ion transport);GO:0099132(ATP hydrolysis coupled cation transmembrane transport);GO:0015078(hydrogen ion transmembrane transporter activity);GO:0015992(proton transport);GO:0015986(ATP synthesis coupled proton transport);GO:0070062(extracellular exosome);GO:0016887(ATPase activity);GO:0000276(mitochondrial proton-transporting ATP synthase complex, coupling factor F(o));GO:0006754(ATP biosynthetic process);GO:0046933(proton-transporting ATP synthase activity, rotational mechanism);GO:0022857(transmembrane transporter activity);GO:0042407(cristae formation);GO:0042776(mitochondrial ATP synthesis coupled proton transport);GO:0005753(mitochondrial proton-transporting ATP synthase complex);GO:0045263(proton-transporting ATP synthase complex, coupling factor F(o))","00190(Oxidative phosphorylation)","NA","NA","ATP synthase, H+ transporting, mitochondrial Fo complex subunit G [Source:HGNC Symbol;Acc:HGNC:14247]",{"v":5.872619,"d":"5.87"},{"v":0.896195,"d":"0.90"},{"v":6.55283615730951,"d":"6.55"},{"v":2.71211946000638,"d":"2.71"},{"v":0.000116543822427192,"d":"0.00"},{"v":0.00281396257101108,"d":"0.00"},"up","yes"]
[124384,0,"chr20","-",46684365,46689779,"ENST00000372114",2,3515,"ENSG00000172315","TP53RK","GO:0005634(nucleus);GO:0016020(membrane);GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0016740(transferase activity);GO:0008033(tRNA processing);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0016787(hydrolase activity);GO:0016773(phosphotransferase activity, alcohol group as acceptor);GO:0005515(protein binding);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:1901796(regulation of signal transduction by p53 class mediator);GO:0000408(EKC/KEOPS complex);GO:0002039(p53 binding);GO:0070525(tRNA threonylcarbamoyladenosine metabolic process)","NA","NA","NA","TP53 regulating kinase [Source:HGNC Symbol;Acc:HGNC:16197]",{"v":3.638981,"d":"3.64"},{"v":0.576504,"d":"0.58"},{"v":6.31215221403494,"d":"6.31"},{"v":2.65813199555821,"d":"2.66"},{"v":1.17770304755787E-4,"d":"0.00"},{"v":0.00284014184222651,"d":"0.00"},"up","yes"]
[42898,0,"chr12","+",56116586,56117943,"ENST00000546591",3,699,"MSTRG.3447","RPL41","GO:0006412(translation);GO:0030529(intracellular ribonucleoprotein complex);GO:0003735(structural constituent of ribosome);GO:0005840(ribosome);GO:0005829(cytosol);GO:0006413(translational initiation);GO:0003723(RNA binding);GO:0006364(rRNA processing);GO:0000184(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay);GO:0019083(viral transcription);GO:0003730(mRNA 3'-UTR binding);GO:0048027(mRNA 5'-UTR binding);GO:0006614(SRP-dependent cotranslational protein targeting to membrane);GO:0022625(cytosolic large ribosomal subunit)","03010(Ribosome)","K02928","NA","ribosomal protein L41 [Source:HGNC Symbol;Acc:HGNC:10354]",{"v":31.726727,"d":"31.73"},{"v":211.102493,"d":"211.10"},{"v":0.150290631574872,"d":"0.15"},{"v":-2.73417301378824,"d":"-2.73"},{"v":1.18726642935826E-4,"d":"0.00"},{"v":0.00285975103274135,"d":"0.00"},"down","yes"]
[31077,0,"chr11","-",65120630,65122057,"ENST00000531743",4,697,"MSTRG.2528","FAU","GO:0003723(RNA binding);GO:0006412(translation);GO:0030529(intracellular ribonucleoprotein complex);GO:0005622(intracellular);GO:0003735(structural constituent of ribosome);GO:0005840(ribosome);GO:0022627(cytosolic small ribosomal subunit);GO:0005615(extracellular space);GO:0008150(biological_process);GO:0005575(cellular_component);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0002227(innate immune response in mucosa);GO:0019731(antibacterial humoral response);GO:0050830(defense response to Gram-positive bacterium);GO:0061844(antimicrobial humoral immune response mediated by antimicrobial peptide);GO:0006413(translational initiation);GO:0006364(rRNA processing);GO:0000184(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay);GO:0019083(viral transcription);GO:0006614(SRP-dependent cotranslational protein targeting to membrane);GO:0015935(small ribosomal subunit)","03010(Ribosome)","NA","NA","FAU, ubiquitin like and ribosomal protein S30 fusion [Source:HGNC Symbol;Acc:HGNC:3597]",{"v":1.109545,"d":"1.11"},{"v":7.97238,"d":"7.97"},{"v":0.139173621929712,"d":"0.14"},{"v":-2.84504229690016,"d":"-2.85"},{"v":1.19286544709526E-4,"d":"0.00"},{"v":0.00286977557199978,"d":"0.00"},"down","yes"]
[165615,0,"chr6","+",36291390,36312229,"ENST00000636260",8,1787,"ENSG00000180316","PNPLA1","GO:0005737(cytoplasm);GO:0016787(hydrolase activity);GO:0006629(lipid metabolic process);GO:0008152(metabolic process);GO:0016042(lipid catabolic process);GO:0016020(membrane);GO:0004806(triglyceride lipase activity);GO:0019433(triglyceride catabolic process);GO:0055088(lipid homeostasis);GO:0005811(lipid particle)","NA","NA","NA","patatin like phospholipase domain containing 1 [Source:HGNC Symbol;Acc:HGNC:21246]",{"v":0.354086,"d":"0.35"},{"v":2.579409,"d":"2.58"},{"v":0.137274081000725,"d":"0.14"},{"v":-2.86486884188334,"d":"-2.86"},{"v":0.000120221916101086,"d":"0.00"},{"v":0.00288879809952645,"d":"0.00"},"down","yes"]
[46089,0,"chr12","-",105177110,105233154,"ENST00000547809",18,1797,"MSTRG.3668","APPL2","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005515(protein binding);GO:0007165(signal transduction);GO:0007049(cell cycle);GO:0005768(endosome);GO:0070062(extracellular exosome);GO:0008283(cell proliferation);GO:0010008(endosome membrane);GO:0031901(early endosome membrane);GO:0016581(NuRD complex)","NA","NA","NA","adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2 [Source:HGNC Symbol;Acc:HGNC:18242]",{"v":2.886457,"d":"2.89"},{"v":0.433406,"d":"0.43"},{"v":6.65993779504668,"d":"6.66"},{"v":2.73550870234207,"d":"2.74"},{"v":1.21830247100638E-4,"d":"0.00"},{"v":0.00292392593041532,"d":"0.00"},"up","yes"]
[161108,0,"chr5","-",172768090,172771195,"ENST00000239223",4,2019,"MSTRG.12537","DUSP1","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016787(hydrolase activity);GO:0004725(protein tyrosine phosphatase activity);GO:0008138(protein tyrosine/serine/threonine phosphatase activity);GO:0016791(phosphatase activity);GO:0006470(protein dephosphorylation);GO:0016311(dephosphorylation);GO:0004721(phosphoprotein phosphatase activity);GO:0005515(protein binding);GO:0017017(MAP kinase tyrosine/serine/threonine phosphatase activity);GO:0007049(cell cycle);GO:0035335(peptidyl-tyrosine dephosphorylation);GO:0006979(response to oxidative stress);GO:0042981(regulation of apoptotic process);GO:0035970(peptidyl-threonine dephosphorylation);GO:0043407(negative regulation of MAP kinase activity);GO:0043409(negative regulation of MAPK cascade);GO:0004726(non-membrane spanning protein tyrosine phosphatase activity);GO:0008330(protein tyrosine/threonine phosphatase activity);GO:0019838(growth factor binding);GO:0000188(inactivation of MAPK activity);GO:0001706(endoderm formation);GO:0009416(response to light stimulus);GO:0010033(response to organic substance);GO:0032355(response to estradiol);GO:0032526(response to retinoic acid);GO:0032870(cellular response to hormone stimulus);GO:0033574(response to testosterone);GO:0035556(intracellular signal transduction);GO:0042542(response to hydrogen peroxide);GO:0043065(positive regulation of apoptotic process);GO:0043066(negative regulation of apoptotic process);GO:0051384(response to glucocorticoid);GO:0051447(negative regulation of meiotic cell cycle);GO:0051591(response to cAMP);GO:0051592(response to calcium ion);GO:0070373(negative regulation of ERK1 and ERK2 cascade);GO:0071850(mitotic cell cycle arrest);GO:0090266(regulation of mitotic cell cycle spindle assembly checkpoint);GO:2000279(negative regulation of DNA biosynthetic process)","04010(MAPK signaling pathway);04726(Serotonergic synapse);05418(Fluid shear stress and atherosclerosis)","K21278","EC:3.1.3.16;EC:3.1.3.48","dual specificity phosphatase 1 [Source:HGNC Symbol;Acc:HGNC:3064]",{"v":6.222978,"d":"6.22"},{"v":41.299473,"d":"41.30"},{"v":0.150679356126409,"d":"0.15"},{"v":-2.73044632131038,"d":"-2.73"},{"v":1.22582678135021E-4,"d":"0.00"},{"v":0.00293845248139267,"d":"0.00"},"down","yes"]
[171517,0,"chr7","+",5190273,5231470,"ENST00000382384",12,1948,"MSTRG.13466","WIPI2","GO:0016020(membrane);GO:0006914(autophagy);GO:0005829(cytosol);GO:0005515(protein binding);GO:0032266(phosphatidylinositol-3-phosphate binding);GO:0080025(phosphatidylinositol-3,5-bisphosphate binding);GO:0000045(autophagosome assembly);GO:0034497(protein localization to pre-autophagosomal structure);GO:0061739(protein lipidation involved in autophagosome assembly);GO:0098792(xenophagy);GO:0000407(pre-autophagosomal structure);GO:0005776(autophagosome);GO:0034045(pre-autophagosomal structure membrane);GO:0000422(mitophagy);GO:0006497(protein lipidation);GO:0044804(nucleophagy);GO:0019898(extrinsic component of membrane);GO:0016236(macroautophagy);GO:0043234(protein complex)","04140(Autophagy - animal);04136(Autophagy - other eukaryotes)","K17908","NA","WD repeat domain, phosphoinositide interacting 2 [Source:HGNC Symbol;Acc:HGNC:32225]",{"v":5.017037,"d":"5.02"},{"v":0.795268,"d":"0.80"},{"v":6.30861168813532,"d":"6.31"},{"v":2.65732255179853,"d":"2.66"},{"v":0.000123063718219002,"d":"0.00"},{"v":2.94334193384927E-3,"d":"0.00"},"up","yes"]
[75123,0,"chr16","+",70113626,70162537,"ENST00000288050",19,9255,"MSTRG.6088","PDPR","GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0016311(dephosphorylation);GO:0005739(mitochondrion);GO:0005759(mitochondrial matrix);GO:0010510(regulation of acetyl-CoA biosynthetic process from pyruvate);GO:0004741([pyruvate dehydrogenase (lipoamide)] phosphatase activity)","NA","NA","NA","pyruvate dehydrogenase phosphatase regulatory subunit [Source:HGNC Symbol;Acc:HGNC:30264]",{"v":0.206706,"d":"0.21"},{"v":1.412261,"d":"1.41"},{"v":0.146365296499726,"d":"0.15"},{"v":-2.7723545665572,"d":"-2.77"},{"v":1.23081456067916E-4,"d":"0.00"},{"v":2.94334193384927E-3,"d":"0.00"},"down","yes"]
[83488,0,"chr17","-",42189089,42194484,"ENST00000587427",10,2396,"ENSG00000167925","GHDC","GO:0005634(nucleus);GO:0016020(membrane);GO:0005783(endoplasmic reticulum);GO:0005576(extracellular region);GO:0003674(molecular_function);GO:0008150(biological_process);GO:0043312(neutrophil degranulation);GO:0034774(secretory granule lumen);GO:0035580(specific granule lumen);GO:0005635(nuclear envelope)","NA","NA","NA","GH3 domain containing [Source:HGNC Symbol;Acc:HGNC:24438]",{"v":0.37279,"d":"0.37"},{"v":2.634214,"d":"2.63"},{"v":0.141518494700886,"d":"0.14"},{"v":-2.82093748727431,"d":"-2.82"},{"v":0.000124298892866974,"d":"0.00"},{"v":0.00296889987173175,"d":"0.00"},"down","yes"]
[96854,0,"chr19","-",11574660,11578985,"ENST00000218758",7,1630,"MSTRG.7834","ACP5","GO:0046872(metal ion binding);GO:0016787(hydrolase activity);GO:0003993(acid phosphatase activity);GO:0005764(lysosome);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0016021(integral component of membrane);GO:0008198(ferrous iron binding);GO:0008199(ferric iron binding);GO:0006771(riboflavin metabolic process);GO:0016311(dephosphorylation);GO:0032496(response to lipopolysaccharide);GO:0032691(negative regulation of interleukin-1 beta production);GO:0032695(negative regulation of interleukin-12 production);GO:0032720(negative regulation of tumor necrosis factor production);GO:0032929(negative regulation of superoxide anion generation);GO:0034097(response to cytokine);GO:0045019(negative regulation of nitric oxide biosynthetic process);GO:0045453(bone resorption);GO:0050728(negative regulation of inflammatory response);GO:0050830(defense response to Gram-positive bacterium);GO:0060349(bone morphogenesis)","00740(Riboflavin metabolism);04142(Lysosome);04380(Osteoclast differentiation);05323(Rheumatoid arthritis)","K14379","EC:3.1.3.2","acid phosphatase 5, tartrate resistant [Source:HGNC Symbol;Acc:HGNC:124]",{"v":0.997398,"d":"1.00"},{"v":6.852858,"d":"6.85"},{"v":0.145544822320848,"d":"0.15"},{"v":-2.7804645776177,"d":"-2.78"},{"v":0.000124685351693616,"d":"0.00"},{"v":2.9731384795023E-3,"d":"0.00"},"down","yes"]
[164513,0,"chr6","-",31639028,31652393,"ENST00000375976",25,3644,"MSTRG.12876","BAG6","GO:0006810(transport);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0043231(intracellular membrane-bounded organelle);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0016569(covalent chromatin modification);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0006915(apoptotic process);GO:0006511(ubiquitin-dependent protein catabolic process);GO:0030154(cell differentiation);GO:0043022(ribosome binding);GO:0002376(immune system process);GO:0007283(spermatogenesis);GO:0070062(extracellular exosome);GO:0050821(protein stabilization);GO:0007130(synaptonemal complex assembly);GO:0031625(ubiquitin protein ligase binding);GO:0005102(receptor binding);GO:0032435(negative regulation of proteasomal ubiquitin-dependent protein catabolic process);GO:0030433(ubiquitin-dependent ERAD pathway);GO:0030101(natural killer cell activation);GO:0007420(brain development);GO:0009790(embryo development);GO:0070628(proteasome binding);GO:0071712(ER-associated misfolded protein catabolic process);GO:0070059(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress);GO:0002429(immune response-activating cell surface receptor signaling pathway);GO:0042771(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator);GO:1990381(ubiquitin-specific protease binding);GO:0001822(kidney development);GO:0045861(negative regulation of proteolysis);GO:0015643(toxic substance binding);GO:0030324(lung development);GO:0071816(tail-anchored membrane protein insertion into ER membrane);GO:0071818(BAT3 complex);GO:0010498(proteasomal protein catabolic process);GO:0031593(polyubiquitin binding);GO:0051787(misfolded protein binding);GO:0018393(internal peptidyl-lysine acetylation);GO:0061857(endoplasmic reticulum stress-induced pre-emptive quality control);GO:1904294(positive regulation of ERAD pathway);GO:1904378(maintenance of unfolded protein involved in ERAD pathway);GO:1904379(protein localization to cytosolic proteasome complex involved in ERAD pathway);GO:0030544(Hsp70 protein binding);GO:0042127(regulation of cell proliferation);GO:0042981(regulation of apoptotic process);GO:0043066(negative regulation of apoptotic process)","NA","NA","NA","BCL2 associated athanogene 6 [Source:HGNC Symbol;Acc:HGNC:13919]",{"v":4.607422,"d":"4.61"},{"v":30.482449,"d":"30.48"},{"v":0.151149994542761,"d":"0.15"},{"v":-2.72594716800994,"d":"-2.73"},{"v":0.000124785469613971,"d":"0.00"},{"v":2.9731384795023E-3,"d":"0.00"},"down","yes"]
[56737,0,"chr14","-",74056850,74084493,"ENST00000553458",12,5499,"MSTRG.4537","ALDH6A1","GO:0003723(RNA binding);GO:0005654(nucleoplasm);GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0005739(mitochondrion);GO:0008152(metabolic process);GO:0004491(methylmalonate-semialdehyde dehydrogenase (acylating) activity);GO:0050873(brown fat cell differentiation);GO:0070062(extracellular exosome);GO:0005759(mitochondrial matrix);GO:0009083(branched-chain amino acid catabolic process);GO:0000062(fatty-acyl-CoA binding);GO:0018478(malonate-semialdehyde dehydrogenase (acetylating) activity);GO:0006210(thymine catabolic process);GO:0006573(valine metabolic process);GO:0006574(valine catabolic process);GO:0019859(thymine metabolic process)","00640(Propanoate metabolism);00562(Inositol phosphate metabolism);00280(Valine, leucine and isoleucine degradation);00410(beta-Alanine metabolism)","K00140","EC:1.2.1.18;EC:1.2.1.27","aldehyde dehydrogenase 6 family member A1 [Source:HGNC Symbol;Acc:HGNC:7179]",{"v":1.119177,"d":"1.12"},{"v":0.17337,"d":"0.17"},{"v":6.45542481398166,"d":"6.46"},{"v":2.69051203850045,"d":"2.69"},{"v":1.24923036072838E-4,"d":"0.00"},{"v":2.9731384795023E-3,"d":"0.00"},"up","yes"]
[112430,"j","chr2","+",96266390,96272173,"MSTRG.8972.5",6,2412,"MSTRG.8972","CIAO1","NA","NA","NA","NA","NA",{"v":5.911505,"d":"5.91"},{"v":0.949275,"d":"0.95"},{"v":6.22738932343104,"d":"6.23"},{"v":2.63862747632865,"d":"2.64"},{"v":0.000125474762141519,"d":"0.00"},{"v":0.00298271434576411,"d":"0.00"},"up","yes"]
[117548,0,"chr2","-",196194370,196592611,"ENST00000260983",29,11809,"ENSG00000138411","HECW2","GO:0005737(cytoplasm);GO:0016740(transferase activity);GO:0016567(protein ubiquitination);GO:0004842(ubiquitin-protein transferase activity);GO:0005856(cytoskeleton);GO:0005819(spindle);GO:0061630(ubiquitin protein ligase activity);GO:0043161(proteasome-mediated ubiquitin-dependent protein catabolic process);GO:0005515(protein binding);GO:0042787(protein ubiquitination involved in ubiquitin-dependent protein catabolic process);GO:0072686(mitotic spindle);GO:0030071(regulation of mitotic metaphase/anaphase transition)","NA","NA","NA","HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2 [Source:HGNC Symbol;Acc:HGNC:29853]",{"v":0.101398,"d":"0.10"},{"v":0.706906,"d":"0.71"},{"v":0.143439155983964,"d":"0.14"},{"v":-2.80148919056267,"d":"-2.80"},{"v":0.000125665720591759,"d":"0.00"},{"v":0.00298370167512039,"d":"0.00"},"down","yes"]
[90399,0,"chr18","-",5289019,5296040,"ENST00000357006",4,3528,"ENSG00000198081","ZBTB14","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0005730(nucleolus);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0005515(protein binding);GO:0016235(aggresome);GO:0043565(sequence-specific DNA binding);GO:0044212(transcription regulatory region DNA binding);GO:0045892(negative regulation of transcription, DNA-templated);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:0001078(transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0003170(heart valve development);GO:0003279(cardiac septum development);GO:0060976(coronary vasculature development)","NA","NA","NA","zinc finger and BTB domain containing 14 [Source:HGNC Symbol;Acc:HGNC:12860]",{"v":4.208517,"d":"4.21"},{"v":0.674927,"d":"0.67"},{"v":6.23551435933071,"d":"6.24"},{"v":2.64050857096896,"d":"2.64"},{"v":1.2674764461118E-4,"d":"0.00"},{"v":0.00300289061418539,"d":"0.00"},"up","yes"]
[177585,0,"chr7","-",106269155,106284632,"ENST00000484527",5,833,"MSTRG.13893","NAMPT","GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016607(nuclear speck);GO:0016740(transferase activity);GO:0016757(transferase activity, transferring glycosyl groups);GO:0030054(cell junction);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0048511(rhythmic process);GO:0005125(cytokine activity);GO:0005615(extracellular space);GO:0009435(NAD biosynthetic process);GO:0019363(pyridine nucleotide biosynthetic process);GO:0004514(nicotinate-nucleotide diphosphorylase (carboxylating) activity);GO:0008144(drug binding);GO:0042803(protein homodimerization activity);GO:0047280(nicotinamide phosphoribosyltransferase activity);GO:0007565(female pregnancy);GO:0007623(circadian rhythm);GO:0014070(response to organic cyclic compound);GO:0032922(circadian regulation of gene expression);GO:0048661(positive regulation of smooth muscle cell proliferation);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0007165(signal transduction);GO:0007267(cell-cell signaling);GO:0051770(positive regulation of nitric-oxide synthase biosynthetic process);GO:0008284(positive regulation of cell proliferation);GO:0034356(NAD biosynthesis via nicotinamide riboside salvage pathway)","00760(Nicotinate and nicotinamide metabolism);04621(NOD-like receptor signaling pathway)","NA","NA","nicotinamide phosphoribosyltransferase [Source:HGNC Symbol;Acc:HGNC:30092]",{"v":1.94527,"d":"1.95"},{"v":13.370822,"d":"13.37"},{"v":0.145486193743361,"d":"0.15"},{"v":-2.78104584321806,"d":"-2.78"},{"v":1.26774678874113E-4,"d":"0.00"},{"v":0.00300289061418539,"d":"0.00"},"down","yes"]
[32905,0,"chr11","+",73376264,73397472,"ENST00000064780",11,3535,"MSTRG.2671","RELT","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005886(plasma membrane);GO:0006955(immune response);GO:0005887(integral component of plasma membrane);GO:0006954(inflammatory response);GO:0070062(extracellular exosome);GO:0097190(apoptotic signaling pathway);GO:0033209(tumor necrosis factor-mediated signaling pathway);GO:0005031(tumor necrosis factor-activated receptor activity);GO:0007275(multicellular organism development);GO:0032496(response to lipopolysaccharide);GO:0042127(regulation of cell proliferation);GO:0042981(regulation of apoptotic process)","04060(Cytokine-cytokine receptor interaction)","K05156","NA","RELT, TNF receptor [Source:HGNC Symbol;Acc:HGNC:13764]",{"v":0.387457,"d":"0.39"},{"v":2.662026,"d":"2.66"},{"v":0.145549667809405,"d":"0.15"},{"v":-2.78041654811147,"d":"-2.78"},{"v":1.27773946367307E-4,"d":"0.00"},{"v":0.00302297412448149,"d":"0.00"},"down","yes"]
[71446,0,"chr16","+",28987566,28990454,"ENST00000564447",4,2443,"MSTRG.5787","LAT","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0007165(signal transduction);GO:0009967(positive regulation of signal transduction);GO:0005886(plasma membrane);GO:0043547(positive regulation of GTPase activity);GO:0005515(protein binding);GO:0002376(immune system process);GO:0002250(adaptive immune response);GO:0038095(Fc-epsilon receptor signaling pathway);GO:0042629(mast cell granule);GO:0019901(protein kinase binding);GO:0008180(COP9 signalosome);GO:0000165(MAPK cascade);GO:0050852(T cell receptor signaling pathway);GO:0030168(platelet activation);GO:0042110(T cell activation);GO:0043303(mast cell degranulation);GO:0005088(Ras guanyl-nucleotide exchange factor activity);GO:0005070(SH3/SH2 adaptor activity);GO:0002260(lymphocyte homeostasis);GO:0006954(inflammatory response);GO:0006955(immune response);GO:0007229(integrin-mediated signaling pathway);GO:0007265(Ras protein signal transduction);GO:0010467(gene expression);GO:0019722(calcium-mediated signaling);GO:0035556(intracellular signal transduction);GO:0045860(positive regulation of protein kinase activity);GO:0048872(homeostasis of number of cells);GO:0050863(regulation of T cell activation);GO:0001772(immunological synapse);GO:0005911(cell-cell junction);GO:0045121(membrane raft)","04014(Ras signaling pathway);04015(Rap1 signaling pathway);04064(NF-kappa B signaling pathway);04650(Natural killer cell mediated cytotoxicity);04660(T cell receptor signaling pathway);04658(Th1 and Th2 cell differentiation);04659(Th17 cell differentiation);04664(Fc epsilon RI signaling pathway);04666(Fc gamma R-mediated phagocytosis)","NA","NA","linker for activation of T-cells [Source:HGNC Symbol;Acc:HGNC:18874]",{"v":2.016923,"d":"2.02"},{"v":0.30366,"d":"0.30"},{"v":6.64204373312257,"d":"6.64"},{"v":2.73162722199018,"d":"2.73"},{"v":0.000128341191934944,"d":"0.00"},{"v":0.00303280108941651,"d":"0.00"},"up","yes"]
[34695,0,"chr11","-",105025508,105035149,"ENST00000533400",9,2001,"MSTRG.2820","CASP1","GO:0016787(hydrolase activity);GO:0008233(peptidase activity);GO:0008234(cysteine-type peptidase activity);GO:0006508(proteolysis);GO:0004197(cysteine-type endopeptidase activity);GO:0005739(mitochondrion);GO:0005737(cytoplasm);GO:0042981(regulation of apoptotic process);GO:0005515(protein binding);GO:0016540(protein autoprocessing);GO:0006915(apoptotic process);GO:0005829(cytosol);GO:0050700(CARD domain binding);GO:0071222(cellular response to lipopolysaccharide);GO:0043234(protein complex);GO:0042802(identical protein binding);GO:0071346(cellular response to interferon-gamma);GO:0043123(positive regulation of I-kappaB kinase/NF-kappaB signaling);GO:0007165(signal transduction);GO:0050718(positive regulation of interleukin-1 beta secretion);GO:0071260(cellular response to mechanical stimulus);GO:0043280(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process);GO:0008656(cysteine-type endopeptidase activator activity involved in apoptotic process);GO:0097169(AIM2 inflammasome complex);GO:0019900(kinase binding);GO:0050727(regulation of inflammatory response);GO:0071310(cellular response to organic substance);GO:0004175(endopeptidase activity);GO:0006919(activation of cysteine-type endopeptidase activity involved in apoptotic process);GO:1903265(positive regulation of tumor necrosis factor-mediated signaling pathway);GO:0097153(cysteine-type endopeptidase activity involved in apoptotic process);GO:0072557(IPAF inflammasome complex);GO:0072558(NLRP1 inflammasome complex);GO:0072559(NLRP3 inflammasome complex);GO:0097179(protease inhibitor complex);GO:0001666(response to hypoxia);GO:0009617(response to bacterium);GO:0010506(regulation of autophagy);GO:0016485(protein processing);GO:0032496(response to lipopolysaccharide);GO:0032611(interleukin-1 beta production);GO:0033198(response to ATP);GO:0050715(positive regulation of cytokine secretion);GO:0050717(positive regulation of interleukin-1 alpha secretion);GO:0051882(mitochondrial depolarization);GO:0060081(membrane hyperpolarization);GO:0070269(pyroptosis);GO:0097300(programmed necrotic cell death);GO:1901998(toxin transport);GO:0005576(extracellular region)","04217(Necroptosis);04621(NOD-like receptor signaling pathway);04623(Cytosolic DNA-sensing pathway);05014(Amyotrophic lateral sclerosis (ALS));05132(Salmonella infection);05133(Pertussis);05134(Legionellosis);05164(Influenza A)","K01370","EC:3.4.22.36","caspase 1 [Source:HGNC Symbol;Acc:HGNC:1499]",{"v":5.418931,"d":"5.42"},{"v":0.862671,"d":"0.86"},{"v":6.28157316056759,"d":"6.28"},{"v":2.65112591369124,"d":"2.65"},{"v":0.000128507258936827,"d":"0.00"},{"v":0.00303313587050893,"d":"0.00"},"up","yes"]
[104757,"j","chr19","+",51752002,51771299,"MSTRG.8383.1",4,3389,"MSTRG.8383","FPR2","NA","NA","NA","NA","NA",{"v":1.721269,"d":"1.72"},{"v":11.422026,"d":"11.42"},{"v":0.15069734563728,"d":"0.15"},{"v":-2.73027408916369,"d":"-2.73"},{"v":1.29044964542726E-4,"d":"0.00"},{"v":0.00304223123021152,"d":"0.00"},"down","yes"]
[84459,0,"chr17","-",45263121,45317040,"ENST00000344686",16,4460,"MSTRG.6925","MAP3K14","GO:0005737(cytoplasm);GO:0043231(intracellular membrane-bounded organelle);GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0005634(nucleus);GO:0005829(cytosol);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0000165(MAPK cascade);GO:0016310(phosphorylation);GO:0001650(fibrillar center);GO:0005515(protein binding);GO:0006955(immune response);GO:0000186(activation of MAPKK activity);GO:0004709(MAP kinase kinase kinase activity);GO:0051607(defense response to virus);GO:0033209(tumor necrosis factor-mediated signaling pathway);GO:0038061(NIK/NF-kappaB signaling);GO:0043123(positive regulation of I-kappaB kinase/NF-kappaB signaling);GO:0071260(cellular response to mechanical stimulus);GO:0042981(regulation of apoptotic process);GO:0007346(regulation of mitotic cell cycle);GO:0007249(I-kappaB kinase/NF-kappaB signaling);GO:0031295(T cell costimulation);GO:0031098(stress-activated protein kinase signaling cascade);GO:0023014(signal transduction by protein phosphorylation);GO:0032147(activation of protein kinase activity);GO:0004704(NF-kappaB-inducing kinase activity)","04010(MAPK signaling pathway);04064(NF-kappa B signaling pathway);04668(TNF signaling pathway);04210(Apoptosis);04660(T cell receptor signaling pathway);04672(Intestinal immune network for IgA production);04380(Osteoclast differentiation);05120(Epithelial cell signaling in Helicobacter pylori infection);05166(HTLV-I infection);05169(Epstein-Barr virus infection)","K04466","EC:2.7.11.25","mitogen-activated protein kinase kinase kinase 14 [Source:HGNC Symbol;Acc:HGNC:6853]",{"v":4.691773,"d":"4.69"},{"v":0.759825,"d":"0.76"},{"v":6.17480735695719,"d":"6.17"},{"v":2.62639412787175,"d":"2.63"},{"v":1.29892018724509E-4,"d":"0.00"},{"v":3.05858942204128E-3,"d":"0.00"},"up","yes"]
[196059,"j","chrX","-",20150562,20266721,"MSTRG.15199.2",23,3087,"MSTRG.15199","RPS6KA3","NA","NA","NA","NA","NA",{"v":1.088068,"d":"1.09"},{"v":7.278286,"d":"7.28"},{"v":0.149495087167501,"d":"0.15"},{"v":-2.74183002073518,"d":"-2.74"},{"v":0.000130295259297946,"d":"0.00"},{"v":0.00306447083352343,"d":"0.00"},"down","yes"]
[171577,0,"chr7","-",5622695,5761138,"ENST00000389900",16,3104,"ENSG00000011275","RNF216","GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0016740(transferase activity);GO:0016567(protein ubiquitination);GO:0006915(apoptotic process);GO:0005515(protein binding);GO:0061630(ubiquitin protein ligase activity);GO:0016032(viral process);GO:0043161(proteasome-mediated ubiquitin-dependent protein catabolic process);GO:0070936(protein K48-linked ubiquitination);GO:0032480(negative regulation of type I interferon production);GO:0005634(nucleus);GO:0032648(regulation of interferon-beta production);GO:0050691(regulation of defense response to virus by host)","NA","NA","NA","ring finger protein 216 [Source:HGNC Symbol;Acc:HGNC:21698]",{"v":1.749221,"d":"1.75"},{"v":0.269769,"d":"0.27"},{"v":6.48414384158298,"d":"6.48"},{"v":2.6969160953645,"d":"2.70"},{"v":1.30982089052268E-4,"d":"0.00"},{"v":3.0770004167008E-3,"d":"0.00"},"up","yes"]
[173513,0,"chr7","-",43875915,43907069,"ENST00000453200",6,4042,"MSTRG.13616","URGCP","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005525(GTP binding);GO:0005829(cytosol);GO:0007049(cell cycle)","NA","NA","NA","upregulator of cell proliferation [Source:HGNC Symbol;Acc:HGNC:30890]",{"v":2.137176,"d":"2.14"},{"v":0.338102,"d":"0.34"},{"v":6.32109836676506,"d":"6.32"},{"v":2.66017526577654,"d":"2.66"},{"v":0.000132306044952665,"d":"0.00"},{"v":0.00310445018286112,"d":"0.00"},"up","yes"]
[35091,0,"chr11","+",112024814,112064390,"ENST00000280346",14,4458,"MSTRG.2839","DLAT","GO:0016740(transferase activity);GO:0006099(tricarboxylic acid cycle);GO:0005739(mitochondrion);GO:0016746(transferase activity, transferring acyl groups);GO:0008152(metabolic process);GO:0005515(protein binding);GO:0005759(mitochondrial matrix);GO:0006090(pyruvate metabolic process);GO:0005975(carbohydrate metabolic process);GO:0034641(cellular nitrogen compound metabolic process);GO:0006006(glucose metabolic process);GO:0004742(dihydrolipoyllysine-residue acetyltransferase activity);GO:0045254(pyruvate dehydrogenase complex);GO:0034604(pyruvate dehydrogenase (NAD+) activity);GO:0010510(regulation of acetyl-CoA biosynthetic process from pyruvate);GO:0006086(acetyl-CoA biosynthetic process from pyruvate);GO:0030431(sleep);GO:0005967(mitochondrial pyruvate dehydrogenase complex);GO:0043209(myelin sheath)","00010(Glycolysis / Gluconeogenesis);00020(Citrate cycle (TCA cycle));00620(Pyruvate metabolism)","K00627","EC:2.3.1.12","dihydrolipoamide S-acetyltransferase [Source:HGNC Symbol;Acc:HGNC:2896]",{"v":0.409877,"d":"0.41"},{"v":2.780984,"d":"2.78"},{"v":0.147385601643159,"d":"0.15"},{"v":-2.7623325029688,"d":"-2.76"},{"v":1.33123037799786E-4,"d":"0.00"},{"v":0.00311995401265976,"d":"0.00"},"down","yes"]
[42865,0,"chr12","+",56041853,56044675,"ENST00000356464",4,1183,"MSTRG.3444","RPS26","GO:0003723(RNA binding);GO:0016020(membrane);GO:0006412(translation);GO:0030529(intracellular ribonucleoprotein complex);GO:0005622(intracellular);GO:0003735(structural constituent of ribosome);GO:0005840(ribosome);GO:0005515(protein binding);GO:0022627(cytosolic small ribosomal subunit);GO:0003729(mRNA binding);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0045296(cadherin binding);GO:0070062(extracellular exosome);GO:0006413(translational initiation);GO:0006364(rRNA processing);GO:0000184(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay);GO:0019083(viral transcription);GO:0006614(SRP-dependent cotranslational protein targeting to membrane);GO:0033119(negative regulation of RNA splicing);GO:0015935(small ribosomal subunit)","03010(Ribosome)","K02976","NA","ribosomal protein S26 [Source:HGNC Symbol;Acc:HGNC:10414]",{"v":51.137814,"d":"51.14"},{"v":8.421217,"d":"8.42"},{"v":6.07249688495143,"d":"6.07"},{"v":2.60228984479259,"d":"2.60"},{"v":1.33864869938084E-4,"d":"0.00"},{"v":3.13366204328682E-3,"d":"0.00"},"up","yes"]
[37261,"j","chr12","+",752576,909436,"MSTRG.3007.2",25,7961,"MSTRG.3007","WNK1","NA","NA","NA","NA","NA",{"v":20.209846,"d":"20.21"},{"v":3.345248,"d":"3.35"},{"v":6.0413595643731,"d":"6.04"},{"v":2.59487325419583,"d":"2.59"},{"v":0.000134243489803536,"d":"0.00"},{"v":0.00313884543840399,"d":"0.00"},"up","yes"]
[22908,0,"chr10","-",100981376,100987494,"ENST00000299179",5,747,"MSTRG.1918","MRPL43","GO:0003723(RNA binding);GO:0006412(translation);GO:0030529(intracellular ribonucleoprotein complex);GO:0005840(ribosome);GO:0005739(mitochondrion);GO:0005515(protein binding);GO:0003735(structural constituent of ribosome);GO:0005743(mitochondrial inner membrane);GO:0070125(mitochondrial translational elongation);GO:0070126(mitochondrial translational termination);GO:0005761(mitochondrial ribosome);GO:0005762(mitochondrial large ribosomal subunit)","NA","NA","NA","mitochondrial ribosomal protein L43 [Source:HGNC Symbol;Acc:HGNC:14517]",{"v":1.370331,"d":"1.37"},{"v":9.462911,"d":"9.46"},{"v":0.144810724733647,"d":"0.14"},{"v":-2.78775964200296,"d":"-2.79"},{"v":1.39318255560325E-4,"d":"0.00"},{"v":0.00325369231231412,"d":"0.00"},"down","yes"]
[78336,"j","chr17","-",5499521,5619424,"MSTRG.6364.4",17,7046,"MSTRG.6364","NLRP1","NA","NA","NA","NA","NA",{"v":0.332029,"d":"0.33"},{"v":2.217368,"d":"2.22"},{"v":0.149740142366986,"d":"0.15"},{"v":-2.73946706366874,"d":"-2.74"},{"v":0.000139794483281528,"d":"0.00"},{"v":0.00326100028290367,"d":"0.00"},"down","yes"]
[15551,0,"chr1","+",207496268,207639409,"ENST00000367049",47,7470,"MSTRG.1357","CR1","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0002376(immune system process);GO:0045087(innate immune response);GO:0030449(regulation of complement activation);GO:0005886(plasma membrane);GO:0005887(integral component of plasma membrane);GO:0046718(viral entry into host cell);GO:0070062(extracellular exosome);GO:0016032(viral process);GO:0002430(complement receptor mediated signaling pathway);GO:0043312(neutrophil degranulation);GO:0006958(complement activation, classical pathway);GO:0009986(cell surface);GO:0030667(secretory granule membrane);GO:0001618(virus receptor activity);GO:0101003(ficolin-1-rich granule membrane);GO:0045589(regulation of regulatory T cell differentiation);GO:1900005(positive regulation of serine-type endopeptidase activity);GO:1900004(negative regulation of serine-type endopeptidase activity);GO:0001851(complement component C3b binding);GO:0001855(complement component C4b binding);GO:0001861(complement component C4b receptor activity);GO:0004877(complement component C3b receptor activity);GO:0045957(negative regulation of complement activation, alternative pathway);GO:0045959(negative regulation of complement activation, classical pathway)","04640(Hematopoietic cell lineage);04610(Complement and coagulation cascades);05134(Legionellosis);05152(Tuberculosis);05144(Malaria);05140(Leishmaniasis)","K04011","NA","complement C3b/C4b receptor 1 (Knops blood group) [Source:HGNC Symbol;Acc:HGNC:2334]",{"v":1.040147,"d":"1.04"},{"v":6.805304,"d":"6.81"},{"v":0.152843576128267,"d":"0.15"},{"v":-2.7098721765038,"d":"-2.71"},{"v":1.40716101499602E-4,"d":"0.00"},{"v":0.0032770555208293,"d":"0.00"},"down","yes"]
[83435,0,"chr17","+",42020051,42025058,"ENST00000393885",4,1909,"MSTRG.6817","NKIRAS2","GO:0005525(GTP binding);GO:0016020(membrane);GO:0007165(signal transduction);GO:0005737(cytoplasm);GO:0000166(nucleotide binding);GO:0003924(GTPase activity);GO:0005575(cellular_component);GO:0007249(I-kappaB kinase/NF-kappaB signaling)","NA","NA","NA","NFKB inhibitor interacting Ras like 2 [Source:HGNC Symbol;Acc:HGNC:17898]",{"v":4.333522,"d":"4.33"},{"v":0.687775,"d":"0.69"},{"v":6.30078441350732,"d":"6.30"},{"v":2.65553144750632,"d":"2.66"},{"v":1.40810979410634E-4,"d":"0.00"},{"v":0.0032770555208293,"d":"0.00"},"up","yes"]
[3249,0,"chr1","+",27344873,27353930,"ENST00000543823",14,2229,"MSTRG.295","SYTL1","GO:0005622(intracellular);GO:0006886(intracellular protein transport);GO:0006887(exocytosis);GO:0017137(Rab GTPase binding);GO:0016020(membrane);GO:0005886(plasma membrane);GO:0042470(melanosome);GO:0098793(presynapse);GO:0005509(calcium ion binding);GO:0005544(calcium-dependent phospholipid binding);GO:0019905(syntaxin binding);GO:0030276(clathrin binding);GO:0006906(vesicle fusion);GO:0017158(regulation of calcium ion-dependent exocytosis);GO:0048791(calcium ion-regulated exocytosis of neurotransmitter);GO:0070382(exocytic vesicle);GO:0005515(protein binding);GO:0070062(extracellular exosome);GO:0061024(membrane organization);GO:0019897(extrinsic component of plasma membrane);GO:0042043(neurexin family protein binding);GO:0031528(microvillus membrane)","NA","NA","NA","synaptotagmin like 1 [Source:HGNC Symbol;Acc:HGNC:15584]",{"v":2.944736,"d":"2.94"},{"v":0.462109,"d":"0.46"},{"v":6.3723840046396,"d":"6.37"},{"v":2.67183320736803,"d":"2.67"},{"v":1.41680848750184E-4,"d":"0.00"},{"v":0.0032934612198413,"d":"0.00"},"up","yes"]
[3289,"j","chr1","-",27612589,27635200,"MSTRG.298.8",10,3014,"MSTRG.298","FGR","NA","NA","NA","NA","NA",{"v":3.024022,"d":"3.02"},{"v":19.693075,"d":"19.69"},{"v":0.153557633838291,"d":"0.15"},{"v":-2.70314785983253,"d":"-2.70"},{"v":0.000145442221825612,"d":"0.00"},{"v":0.00337696544815559,"d":"0.00"},"down","yes"]
[114393,0,"chr2","-",130338241,130342349,"ENST00000259229",5,1646,"MSTRG.9104","CCDC115","GO:0016020(membrane);GO:0005783(endoplasmic reticulum);GO:0005764(lysosome);GO:0031410(cytoplasmic vesicle);GO:0006879(cellular iron ion homeostasis);GO:0005768(endosome);GO:0005793(endoplasmic reticulum-Golgi intermediate compartment);GO:0036295(cellular response to increased oxygen levels);GO:0007042(lysosomal lumen acidification);GO:0051082(unfolded protein binding);GO:1905146(lysosomal protein catabolic process);GO:0030137(COPI-coated vesicle);GO:0016471(vacuolar proton-transporting V-type ATPase complex);GO:0042406(extrinsic component of endoplasmic reticulum membrane)","NA","NA","NA","coiled-coil domain containing 115 [Source:HGNC Symbol;Acc:HGNC:28178]",{"v":1.724485,"d":"1.72"},{"v":11.385623,"d":"11.39"},{"v":0.15146162840628,"d":"0.15"},{"v":-2.72297575016403,"d":"-2.72"},{"v":0.000146315050776409,"d":"0.00"},{"v":0.00339328563751839,"d":"0.00"},"down","yes"]
[17959,0,"chr10","+",180013,249261,"ENST00000558098",13,1859,"ENSG00000015171","ZMYND11","GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0005654(nucleoplasm);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0016569(covalent chromatin modification);GO:0003677(DNA binding);GO:0005694(chromosome);GO:0008270(zinc ion binding);GO:0005515(protein binding);GO:0007049(cell cycle);GO:0003682(chromatin binding);GO:1903507(negative regulation of nucleic acid-templated transcription);GO:0051607(defense response to virus);GO:0003714(transcription corepressor activity);GO:0000977(RNA polymerase II regulatory region sequence-specific DNA binding);GO:0016032(viral process);GO:0003690(double-stranded DNA binding);GO:0046329(negative regulation of JNK cascade);GO:0008283(cell proliferation);GO:0035064(methylated histone binding);GO:0043124(negative regulation of I-kappaB kinase/NF-kappaB signaling);GO:0042393(histone binding);GO:2001237(negative regulation of extrinsic apoptotic signaling pathway);GO:0003712(transcription cofactor activity);GO:0034243(regulation of transcription elongation from RNA polymerase II promoter);GO:0016020(membrane);GO:0016021(integral component of membrane)","NA","NA","NA","zinc finger MYND-type containing 11 [Source:HGNC Symbol;Acc:HGNC:16966]",{"v":4.386971,"d":"4.39"},{"v":0.701602,"d":"0.70"},{"v":6.25279146866742,"d":"6.25"},{"v":2.64450040400165,"d":"2.64"},{"v":1.46664258633963E-4,"d":"0.00"},{"v":0.00339743841810089,"d":"0.00"},"up","yes"]
[2681,0,"chr1","+",23743366,23762040,"ENST00000613537",11,4924,"MSTRG.233","ELOA","GO:0005634(nucleus);GO:0016021(integral component of membrane);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0005515(protein binding);GO:0005615(extracellular space);GO:0005654(nucleoplasm);GO:0006368(transcription elongation from RNA polymerase II promoter);GO:0070449(elongin complex);GO:0006366(transcription from RNA polymerase II promoter);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0003746(translation elongation factor activity);GO:0006414(translational elongation)","NA","NA","NA","elongin A [Source:HGNC Symbol;Acc:HGNC:11620]",{"v":0.191356,"d":"0.19"},{"v":1.314203,"d":"1.31"},{"v":0.145606120211261,"d":"0.15"},{"v":-2.77985709777886,"d":"-2.78"},{"v":1.47930598145853E-4,"d":"0.00"},{"v":0.00342154406773142,"d":"0.00"},"down","yes"]
[58991,0,"chr14","+",103126389,103135651,"ENST00000559406",11,1799,"MSTRG.4696","TNFAIP2","GO:0006887(exocytosis);GO:0000145(exocyst);GO:0007275(multicellular organism development);GO:0030154(cell differentiation);GO:0000149(SNARE binding);GO:0005615(extracellular space);GO:0001525(angiogenesis);GO:0051601(exocyst localization)","NA","NA","NA","TNF alpha induced protein 2 [Source:HGNC Symbol;Acc:HGNC:11895]",{"v":2.409236,"d":"2.41"},{"v":15.764456,"d":"15.76"},{"v":0.152827094065282,"d":"0.15"},{"v":-2.71002775957325,"d":"-2.71"},{"v":1.48245817162933E-4,"d":"0.00"},{"v":0.00342154406773142,"d":"0.00"},"down","yes"]
[200261,0,"chrX","-",136216811,136251579,"ENST00000316077",19,4567,"ENSG00000129680","MAP7D3","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005856(cytoskeleton);GO:0000226(microtubule cytoskeleton organization);GO:0008017(microtubule binding);GO:0005819(spindle);GO:0015630(microtubule cytoskeleton);GO:0005198(structural molecule activity);GO:0015631(tubulin binding);GO:0046785(microtubule polymerization)","NA","NA","NA","MAP7 domain containing 3 [Source:HGNC Symbol;Acc:HGNC:25742]",{"v":1.621443,"d":"1.62"},{"v":0.257995,"d":"0.26"},{"v":6.28478458884862,"d":"6.28"},{"v":2.65186329708402,"d":"2.65"},{"v":0.000148302041524093,"d":"0.00"},{"v":0.00342154406773142,"d":"0.00"},"up","yes"]
[69989,0,"chr16","-",15594387,15643024,"ENST00000540441",26,7105,"MSTRG.5695","MARF1","GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0016020(membrane);GO:0005794(Golgi apparatus);GO:0043231(intracellular membrane-bounded organelle);GO:0051321(meiotic cell cycle);GO:0030154(cell differentiation);GO:0005777(peroxisome);GO:0010468(regulation of gene expression);GO:0003674(molecular_function);GO:0010923(negative regulation of phosphatase activity);GO:0048477(oogenesis);GO:0007143(female meiotic nuclear division);GO:0006302(double-strand break repair)","NA","NA","NA","meiosis regulator and mRNA stability factor 1 [Source:HGNC Symbol;Acc:HGNC:29562]",{"v":3.639528,"d":"3.64"},{"v":0.602874,"d":"0.60"},{"v":6.03696294748156,"d":"6.04"},{"v":2.59382294647967,"d":"2.59"},{"v":1.48390282584906E-4,"d":"0.00"},{"v":0.00342154406773142,"d":"0.00"},"up","yes"]
[140166,0,"chr3","+",127672958,127680920,"ENST00000475042",12,1915,"MSTRG.11156","ABTB1","GO:0005737(cytoplasm);GO:0006412(translation);GO:0005730(nucleolus);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0003746(translation elongation factor activity);GO:0006414(translational elongation);GO:0031625(ubiquitin protein ligase binding);GO:0043161(proteasome-mediated ubiquitin-dependent protein catabolic process);GO:0030162(regulation of proteolysis);GO:0042787(protein ubiquitination involved in ubiquitin-dependent protein catabolic process);GO:0019005(SCF ubiquitin ligase complex)","NA","NA","NA","ankyrin repeat and BTB domain containing 1 [Source:HGNC Symbol;Acc:HGNC:18275]",{"v":3.171013,"d":"3.17"},{"v":20.636995,"d":"20.64"},{"v":0.153656721824083,"d":"0.15"},{"v":-2.70221721484126,"d":"-2.70"},{"v":0.000148783811185297,"d":"0.00"},{"v":0.00342411943596794,"d":"0.00"},"down","yes"]
[82305,0,"chr17","+",35809455,35847242,"ENST00000605844",16,2191,"MSTRG.6726","TAF15","GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0005654(nucleoplasm);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0045893(positive regulation of transcription, DNA-templated)","03022(Basal transcription factors);05202(Transcriptional misregulation in cancers)","K14651","NA","TATA-box binding protein associated factor 15 [Source:HGNC Symbol;Acc:HGNC:11547]",{"v":5.892908,"d":"5.89"},{"v":0.962976,"d":"0.96"},{"v":6.11947545940916,"d":"6.12"},{"v":2.61340799531314,"d":"2.61"},{"v":1.4907424817736E-4,"d":"0.00"},{"v":0.00342411943596794,"d":"0.00"},"up","yes"]
[2820,0,"chr1","+",24643308,24671595,"ENST00000479034",17,2671,"MSTRG.255","SRRM1","GO:0006397(mRNA processing);GO:0003723(RNA binding);GO:0008380(RNA splicing);GO:0005634(nucleus);GO:0016607(nuclear speck);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0005681(spliceosomal complex);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0000398(mRNA splicing, via spliceosome);GO:0006369(termination of RNA polymerase II transcription);GO:0006405(RNA export from nucleus);GO:0031124(mRNA 3'-end processing);GO:0016363(nuclear matrix);GO:0000375(RNA splicing, via transesterification reactions);GO:0006406(mRNA export from nucleus);GO:0071013(catalytic step 2 spliceosome)","03013(RNA transport);03015(mRNA surveillance pathway)","NA","NA","serine and arginine repetitive matrix 1 [Source:HGNC Symbol;Acc:HGNC:16638]",{"v":14.073722,"d":"14.07"},{"v":2.340842,"d":"2.34"},{"v":6.01224772966309,"d":"6.01"},{"v":2.58790445552726,"d":"2.59"},{"v":1.49149197433575E-4,"d":"0.00"},{"v":0.00342411943596794,"d":"0.00"},"up","yes"]
[82137,"j","chr17","-",35010042,35089264,"MSTRG.6694.6",6,2775,"MSTRG.6694","AC004223.3","NA","NA","NA","NA","NA",{"v":5.500421,"d":"5.50"},{"v":0.904015,"d":"0.90"},{"v":6.08443554587037,"d":"6.08"},{"v":2.60512343008026,"d":"2.61"},{"v":1.49187896098363E-4,"d":"0.00"},{"v":0.00342411943596794,"d":"0.00"},"up","yes"]
[139057,0,"chr3","-",112120841,112133305,"ENST00000308910",6,3336,"MSTRG.11109","GCSAM","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0003779(actin binding);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0019901(protein kinase binding);GO:0050855(regulation of B cell receptor signaling pathway);GO:2000401(regulation of lymphocyte migration);GO:0045159(myosin II binding);GO:2000402(negative regulation of lymphocyte migration)","NA","NA","NA","germinal center associated signaling and motility [Source:HGNC Symbol;Acc:HGNC:20253]",{"v":2.963892,"d":"2.96"},{"v":0.480788,"d":"0.48"},{"v":6.16465469188083,"d":"6.16"},{"v":2.62402008550188,"d":"2.62"},{"v":0.00015058438432013,"d":"0.00"},{"v":0.00345017854419862,"d":"0.00"},"up","yes"]
[60533,"j","chr15","+",31345319,31377698,"MSTRG.4873.5",3,5014,"MSTRG.4873","KLF13","NA","NA","NA","NA","NA",{"v":2.616662,"d":"2.62"},{"v":0.42793,"d":"0.43"},{"v":6.11469632883883,"d":"6.11"},{"v":2.61228085267633,"d":"2.61"},{"v":0.000150668854694571,"d":"0.00"},{"v":0.00345017854419862,"d":"0.00"},"up","yes"]
[1562,0,"chr1","+",11654901,11663326,"ENST00000251547",6,2903,"ENSG00000132879","FBXO44","GO:0005515(protein binding);GO:0005829(cytosol);GO:0000209(protein polyubiquitination);GO:0043687(post-translational protein modification);GO:0010498(proteasomal protein catabolic process);GO:0004842(ubiquitin-protein transferase activity);GO:0019005(SCF ubiquitin ligase complex)","NA","NA","NA","F-box protein 44 [Source:HGNC Symbol;Acc:HGNC:24847]",{"v":0.321057,"d":"0.32"},{"v":2.198637,"d":"2.20"},{"v":0.146025469415824,"d":"0.15"},{"v":-2.77570807238984,"d":"-2.78"},{"v":1.51800049048596E-4,"d":"0.00"},{"v":0.00347210009095345,"d":"0.00"},"down","yes"]
[77031,0,"chr16","-",89707134,89719369,"ENST00000561976",14,2791,"MSTRG.6253","VPS9D1","GO:0043547(positive regulation of GTPase activity);GO:0005096(GTPase activator activity);GO:0005215(transporter activity);GO:0015986(ATP synthesis coupled proton transport)","NA","NA","NA","VPS9 domain containing 1 [Source:HGNC Symbol;Acc:HGNC:13526]",{"v":2.51352,"d":"2.51"},{"v":0.403019,"d":"0.40"},{"v":6.23672829320702,"d":"6.24"},{"v":2.64078940841538,"d":"2.64"},{"v":1.52095597437091E-4,"d":"0.00"},{"v":3.47487973641171E-3,"d":"0.00"},"up","yes"]
[94041,0,"chr19","-",896504,913245,"ENST00000587975",8,1765,"MSTRG.7582","R3HDM4","GO:0003676(nucleic acid binding);GO:0005634(nucleus)","NA","NA","NA","R3H domain containing 4 [Source:HGNC Symbol;Acc:HGNC:28270]",{"v":1.23851,"d":"1.24"},{"v":8.185127,"d":"8.19"},{"v":0.151312252088453,"d":"0.15"},{"v":-2.72439928438758,"d":"-2.72"},{"v":1.5358895707665E-4,"d":"0.00"},{"v":3.50498776560747E-3,"d":"0.00"},"down","yes"]
[116457,0,"chr2","+",173075842,173227146,"ENST00000338983",12,7179,"ENSG00000091436","MAP3K20","GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0005829(cytosol);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0005515(protein binding);GO:0007049(cell cycle);GO:0000287(magnesium ion binding);GO:0030154(cell differentiation);GO:0004709(MAP kinase kinase kinase activity);GO:0000186(activation of MAPKK activity);GO:0008283(cell proliferation);GO:0007050(cell cycle arrest);GO:0043065(positive regulation of apoptotic process);GO:0008219(cell death);GO:0035556(intracellular signal transduction);GO:0000077(DNA damage checkpoint);GO:0042733(embryonic digit morphogenesis);GO:0006950(response to stress);GO:0009314(response to radiation);GO:0060173(limb development);GO:0007257(activation of JUN kinase activity);GO:0000075(cell cycle checkpoint);GO:0000165(MAPK cascade);GO:0007010(cytoskeleton organization);GO:0005622(intracellular)","04010(MAPK signaling pathway)","K04424","EC:2.7.11.25","mitogen-activated protein kinase kinase kinase 20 [Source:HGNC Symbol;Acc:HGNC:17797]",{"v":0.861608,"d":"0.86"},{"v":0.137224,"d":"0.14"},{"v":6.27884335101731,"d":"6.28"},{"v":2.65049881939718,"d":"2.65"},{"v":0.000154368092269157,"d":"0.00"},{"v":0.0035187466511764,"d":"0.00"},"up","yes"]
[196911,0,"chrX","-",48458693,48460854,"ENST00000615300",4,797,"MSTRG.15266","SLC38A5","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005886(plasma membrane);GO:0003333(amino acid transmembrane transport);GO:0005887(integral component of plasma membrane);GO:0015171(amino acid transmembrane transporter activity);GO:0006865(amino acid transport);GO:0015187(glycine transmembrane transporter activity);GO:0015816(glycine transport)","04727(GABAergic synapse)","NA","NA","solute carrier family 38 member 5 [Source:HGNC Symbol;Acc:HGNC:18070]",{"v":44.547691,"d":"44.55"},{"v":7.455572,"d":"7.46"},{"v":5.97508695509882,"d":"5.98"},{"v":2.5789597087046,"d":"2.58"},{"v":0.000154855799220646,"d":"0.00"},{"v":3.52583876720394E-3,"d":"0.00"},"up","yes"]
[194388,0,"chr9","-",132909811,132944595,"ENST00000493467",12,2219,"MSTRG.15061","TSC1","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005829(cytosol);GO:0005515(protein binding);GO:0005811(lipid particle);GO:0005886(plasma membrane);GO:0030027(lamellipodium);GO:0050821(protein stabilization);GO:0008285(negative regulation of cell proliferation);GO:0061024(membrane organization);GO:0005938(cell cortex);GO:0006417(regulation of translation);GO:0043234(protein complex);GO:0090630(activation of GTPase activity);GO:0005634(nucleus);GO:0017148(negative regulation of translation);GO:0047485(protein N-terminus binding);GO:0032007(negative regulation of TOR signaling);GO:0048471(perinuclear region of cytoplasm);GO:0005884(actin filament);GO:0046627(negative regulation of insulin receptor signaling pathway);GO:0051087(chaperone binding);GO:0007160(cell-matrix adhesion);GO:1901214(regulation of neuron death);GO:0032868(response to insulin);GO:0007050(cell cycle arrest);GO:0008344(adult locomotory behavior);GO:0051492(regulation of stress fiber assembly);GO:0051726(regulation of cell cycle);GO:0051894(positive regulation of focal adhesion assembly);GO:0001952(regulation of cell-matrix adhesion);GO:0033596(TSC1-TSC2 complex);GO:0016242(negative regulation of macroautophagy);GO:0032794(GTPase activating protein binding);GO:0001822(kidney development);GO:0001843(neural tube closure);GO:0002250(adaptive immune response);GO:0006407(rRNA export from nucleus);GO:0006813(potassium ion transport);GO:0007399(nervous system development);GO:0010977(negative regulation of neuron projection development);GO:0016239(positive regulation of macroautophagy);GO:0021766(hippocampus development);GO:0021987(cerebral cortex development);GO:0030030(cell projection organization);GO:0034260(negative regulation of GTPase activity);GO:0042552(myelination);GO:0043379(memory T cell differentiation);GO:0043666(regulation of phosphoprotein phosphatase activity);GO:0045792(negative regulation of cell size);GO:0045859(regulation of protein kinase activity);GO:0046323(glucose import);GO:0050808(synapse organization);GO:0051291(protein heterooligomerization);GO:0051496(positive regulation of stress fiber assembly);GO:0051893(regulation of focal adhesion assembly);GO:0055007(cardiac muscle cell differentiation);GO:0090650(cellular response to oxygen-glucose deprivation);GO:1903204(negative regulation of oxidative stress-induced neuron death);GO:0005856(cytoskeleton);GO:0030426(growth cone);GO:0042995(cell projection);GO:0043231(intracellular membrane-bounded organelle)","04072(Phospholipase D signaling pathway);04151(PI3K-Akt signaling pathway);04152(AMPK signaling pathway);04150(mTOR signaling pathway);04140(Autophagy - animal);04218(Cellular senescence);04910(Insulin signaling pathway);04211(Longevity regulating pathway - mammal);05231(Choline metabolism in cancer);05165(Human papillomavirus infection)","NA","NA","tuberous sclerosis 1 [Source:HGNC Symbol;Acc:HGNC:12362]",{"v":2.657896,"d":"2.66"},{"v":0.426032,"d":"0.43"},{"v":6.23872385172945,"d":"6.24"},{"v":2.64125095199316,"d":"2.64"},{"v":0.000155141118968595,"d":"0.00"},{"v":3.52831191749989E-3,"d":"0.00"},"up","yes"]
[83047,0,"chr17","+",40122298,40136916,"ENST00000398532",9,4707,"MSTRG.6793","MSL1","GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0016569(covalent chromatin modification);GO:0043984(histone H4-K16 acetylation);GO:0072487(MSL complex)","NA","NA","NA","male specific lethal 1 homolog [Source:HGNC Symbol;Acc:HGNC:27905]",{"v":1.096583,"d":"1.10"},{"v":7.112808,"d":"7.11"},{"v":0.154170195512096,"d":"0.15"},{"v":-2.69740420734475,"d":"-2.70"},{"v":0.000156063560210369,"d":"0.00"},{"v":0.00354525275344784,"d":"0.00"},"down","yes"]
[57010,0,"chr14","+",75661268,75886867,"ENST00000557636",32,4168,"MSTRG.4564","TTLL5","GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0006464(cellular protein modification process);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0006351(transcription, DNA-templated);GO:0005856(cytoskeleton);GO:0042995(cell projection);GO:0016874(ligase activity);GO:0005874(microtubule);GO:0005813(centrosome);GO:0005929(cilium);GO:0070740(tubulin-glutamic acid ligase activity);GO:0018095(protein polyglutamylation);GO:0060041(retina development in camera-type eye);GO:0007283(spermatogenesis);GO:0007288(sperm axoneme assembly);GO:0009566(fertilization);GO:0030317(flagellated sperm motility)","NA","NA","NA","tubulin tyrosine ligase like 5 [Source:HGNC Symbol;Acc:HGNC:19963]",{"v":1.657978,"d":"1.66"},{"v":0.266742,"d":"0.27"},{"v":6.21566157560489,"d":"6.22"},{"v":2.63590795540457,"d":"2.64"},{"v":1.5766437487573E-4,"d":"0.00"},{"v":0.00357754799718021,"d":"0.00"},"up","yes"]
[23025,"j","chr10","-",101785831,101818435,"MSTRG.1926.4",15,3685,"MSTRG.1926","MGEA5","NA","NA","NA","NA","NA",{"v":13.149625,"d":"13.15"},{"v":2.212836,"d":"2.21"},{"v":5.94243088959146,"d":"5.94"},{"v":2.57105321973717,"d":"2.57"},{"v":1.58163558031423E-4,"d":"0.00"},{"v":0.00358480127896874,"d":"0.00"},"up","yes"]
[124805,0,"chr20","+",56412261,56460387,"ENST00000434344",5,2888,"MSTRG.9843","CASS4","GO:0005737(cytoplasm);GO:0007155(cell adhesion);GO:0005856(cytoskeleton);GO:0030054(cell junction);GO:0005925(focal adhesion)","NA","NA","NA","Cas scaffolding protein family member 4 [Source:HGNC Symbol;Acc:HGNC:15878]",{"v":0.780393,"d":"0.78"},{"v":5.136181,"d":"5.14"},{"v":0.151940322975378,"d":"0.15"},{"v":-2.71842330183044,"d":"-2.72"},{"v":0.000158421797807871,"d":"0.00"},{"v":3.58594438851137E-3,"d":"0.00"},"down","yes"]
[17796,0,"chr1","+",247857199,247878205,"ENST00000366481",6,3225,"MSTRG.1507","TRIM58","GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0016740(transferase activity);GO:0016567(protein ubiquitination);GO:0005622(intracellular)","NA","NA","NA","tripartite motif containing 58 [Source:HGNC Symbol;Acc:HGNC:24150]",{"v":22.585623,"d":"22.59"},{"v":3.814689,"d":"3.81"},{"v":5.92069838458653,"d":"5.92"},{"v":2.56576736108284,"d":"2.57"},{"v":1.5859680483856E-4,"d":"0.00"},{"v":3.58594438851137E-3,"d":"0.00"},"up","yes"]
[28874,0,"chr11","-",47572198,47578789,"ENST00000533290",3,3079,"MSTRG.2378","KBTBD4","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0031625(ubiquitin protein ligase binding);GO:0043161(proteasome-mediated ubiquitin-dependent protein catabolic process);GO:0030162(regulation of proteolysis);GO:0042787(protein ubiquitination involved in ubiquitin-dependent protein catabolic process);GO:0019005(SCF ubiquitin ligase complex)","NA","NA","NA","kelch repeat and BTB domain containing 4 [Source:HGNC Symbol;Acc:HGNC:23761]",{"v":0.224461,"d":"0.22"},{"v":1.564448,"d":"1.56"},{"v":0.143476165395079,"d":"0.14"},{"v":-2.80111700204432,"d":"-2.80"},{"v":0.000158752746366389,"d":"0.00"},{"v":3.58594438851137E-3,"d":"0.00"},"down","yes"]
[71420,0,"chr16","+",28974772,28984548,"ENST00000565975",13,1979,"MSTRG.5787","SPNS1","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0055085(transmembrane transport);GO:0006810(transport);GO:0005743(mitochondrial inner membrane);GO:0005765(lysosomal membrane);GO:0005739(mitochondrion);GO:0005515(protein binding);GO:0006869(lipid transport);GO:0031982(vesicle);GO:0040011(locomotion);GO:0046624(sphingolipid transporter activity);GO:0003376(sphingosine-1-phosphate signaling pathway)","NA","NA","NA","sphingolipid transporter 1 (putative) [Source:HGNC Symbol;Acc:HGNC:30621]",{"v":0.911468,"d":"0.91"},{"v":6.038827,"d":"6.04"},{"v":0.150934610314222,"d":"0.15"},{"v":-2.72800443147891,"d":"-2.73"},{"v":0.000159173838485154,"d":"0.00"},{"v":0.00359042099353981,"d":"0.00"},"down","yes"]
[166113,0,"chr6","-",43037620,43053945,"ENST00000535468",26,5504,"ENSG00000044090","CUL7","GO:0005737(cytoplasm);GO:0016567(protein ubiquitination);GO:0005794(Golgi apparatus);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0006508(proteolysis);GO:0006511(ubiquitin-dependent protein catabolic process);GO:0048471(perinuclear region of cytoplasm);GO:0031625(ubiquitin protein ligase binding);GO:0000226(microtubule cytoskeleton organization);GO:0005813(centrosome);GO:0005815(microtubule organizing center);GO:0001890(placenta development);GO:0005829(cytosol);GO:0043687(post-translational protein modification);GO:0016032(viral process);GO:0005680(anaphase-promoting complex);GO:0050775(positive regulation of dendrite morphogenesis);GO:0000281(mitotic cytokinesis);GO:0036498(IRE1-mediated unfolded protein response);GO:0007030(Golgi organization);GO:0007088(regulation of mitotic nuclear division);GO:0001570(vasculogenesis);GO:1990393(3M complex);GO:0001837(epithelial to mesenchymal transition);GO:0031467(Cul7-RING ubiquitin ligase complex)","04120(Ubiquitin mediated proteolysis)","K10613","NA","cullin 7 [Source:HGNC Symbol;Acc:HGNC:21024]",{"v":0.190585,"d":"0.19"},{"v":1.287856,"d":"1.29"},{"v":0.147986265545216,"d":"0.15"},{"v":-2.75646480787952,"d":"-2.76"},{"v":1.59407359563927E-4,"d":"0.00"},{"v":0.00359042099353981,"d":"0.00"},"down","yes"]
[196906,0,"chrX","-",48458537,48470177,"ENST00000595796",16,2659,"MSTRG.15266","SLC38A5","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005886(plasma membrane);GO:0003333(amino acid transmembrane transport);GO:0005887(integral component of plasma membrane);GO:0015171(amino acid transmembrane transporter activity);GO:0006865(amino acid transport);GO:0015187(glycine transmembrane transporter activity);GO:0015816(glycine transport)","04727(GABAergic synapse)","NA","NA","solute carrier family 38 member 5 [Source:HGNC Symbol;Acc:HGNC:18070]",{"v":51.753281,"d":"51.75"},{"v":8.759805,"d":"8.76"},{"v":5.90804030455016,"d":"5.91"},{"v":2.56267966817723,"d":"2.56"},{"v":1.59490355632503E-4,"d":"0.00"},{"v":0.00359042099353981,"d":"0.00"},"up","yes"]
[10731,0,"chr1","-",151050973,151059649,"ENST00000357235",5,3045,"MSTRG.942","CDC42SE1","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005886(plasma membrane);GO:0005856(cytoskeleton);GO:0008360(regulation of cell shape);GO:0007165(signal transduction);GO:0005198(structural molecule activity);GO:0006909(phagocytosis);GO:0005095(GTPase inhibitor activity);GO:0034260(negative regulation of GTPase activity)","NA","NA","NA","CDC42 small effector 1 [Source:HGNC Symbol;Acc:HGNC:17719]",{"v":11.015182,"d":"11.02"},{"v":70.427101,"d":"70.43"},{"v":0.156405443978164,"d":"0.16"},{"v":-2.67663736572284,"d":"-2.68"},{"v":0.00015978736998419,"d":"0.00"},{"v":0.0035930565358607,"d":"0.00"},"down","yes"]
[94322,0,"chr19","+",1426349,1435684,"ENST00000585485",5,3943,"MSTRG.7609","DAZAP1","GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0007275(multicellular organism development);GO:0030154(cell differentiation);GO:0007283(spermatogenesis);GO:0035613(RNA stem-loop binding);GO:0001893(maternal placenta development);GO:0008283(cell proliferation);GO:0048026(positive regulation of mRNA splicing, via spliceosome)","03015(mRNA surveillance pathway)","NA","NA","DAZ associated protein 1 [Source:HGNC Symbol;Acc:HGNC:2683]",{"v":2.058511,"d":"2.06"},{"v":0.334294,"d":"0.33"},{"v":6.15778625999868,"d":"6.16"},{"v":2.62241179154779,"d":"2.62"},{"v":0.000162010165664611,"d":"0.00"},{"v":0.00363894149380309,"d":"0.00"},"up","yes"]
[33006,0,"chr11","-",73974852,73978141,"ENST00000544615",5,1004,"MSTRG.2685","UCP2","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005743(mitochondrial inner membrane);GO:0005739(mitochondrion);GO:0005515(protein binding);GO:0000303(response to superoxide);GO:0001666(response to hypoxia);GO:0006839(mitochondrial transport);GO:0007565(female pregnancy);GO:0007568(aging);GO:0009749(response to glucose);GO:0010942(positive regulation of cell death);GO:0032869(cellular response to insulin stimulus);GO:0032870(cellular response to hormone stimulus);GO:0034198(cellular response to amino acid starvation);GO:0043066(negative regulation of apoptotic process);GO:0051881(regulation of mitochondrial membrane potential);GO:0061179(negative regulation of insulin secretion involved in cellular response to glucose stimulus);GO:0070542(response to fatty acid);GO:0071333(cellular response to glucose stimulus);GO:0097421(liver regeneration);GO:0005737(cytoplasm);GO:0031966(mitochondrial membrane);GO:0015992(proton transport);GO:0009409(response to cold);GO:0017077(oxidative phosphorylation uncoupler activity);GO:1990542(mitochondrial transmembrane transport);GO:1990845(adaptive thermogenesis)","NA","NA","NA","uncoupling protein 2 [Source:HGNC Symbol;Acc:HGNC:12518]",{"v":0.81737,"d":"0.82"},{"v":5.608772,"d":"5.61"},{"v":0.145730651914537,"d":"0.15"},{"v":-2.77862373969378,"d":"-2.78"},{"v":0.000162908591602221,"d":"0.00"},{"v":0.00365500983945297,"d":"0.00"},"down","yes"]
[135635,"j","chr3","+",46979810,47009703,"MSTRG.10884.2",53,8619,"MSTRG.10884","NBEAL2","NA","NA","NA","NA","NA",{"v":2.688649,"d":"2.69"},{"v":17.144171,"d":"17.14"},{"v":0.156825838939661,"d":"0.16"},{"v":-2.67276481452247,"d":"-2.67"},{"v":0.000163729441407482,"d":"0.00"},{"v":3.66930357578518E-3,"d":"0.00"},"down","yes"]
[177862,0,"chr7","+",112423144,112475527,"ENST00000005558",13,1834,"MSTRG.13917","IFRD1","GO:0007275(multicellular organism development);GO:0030154(cell differentiation);GO:0007518(myoblast fate determination);GO:0014706(striated muscle tissue development);GO:0030517(negative regulation of axon extension);GO:0042692(muscle cell differentiation);GO:0043403(skeletal muscle tissue regeneration);GO:0048671(negative regulation of collateral sprouting);GO:0005634(nucleus);GO:0005737(cytoplasm)","NA","NA","NA","interferon related developmental regulator 1 [Source:HGNC Symbol;Acc:HGNC:5456]",{"v":1.664906,"d":"1.66"},{"v":10.803685,"d":"10.80"},{"v":0.154105381635988,"d":"0.15"},{"v":-2.69801085065969,"d":"-2.70"},{"v":1.64761979368908E-4,"d":"0.00"},{"v":0.00368514328120201,"d":"0.00"},"down","yes"]
[70200,0,"chr16","-",18782968,18790362,"ENST00000576008",6,589,"MSTRG.5711","RPS15A","GO:0003723(RNA binding);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0006412(translation);GO:0030529(intracellular ribonucleoprotein complex);GO:0003735(structural constituent of ribosome);GO:0005840(ribosome);GO:0022627(cytosolic small ribosomal subunit);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0009615(response to virus);GO:0031012(extracellular matrix);GO:0005739(mitochondrion);GO:0005515(protein binding);GO:0008284(positive regulation of cell proliferation);GO:0006413(translational initiation);GO:0006364(rRNA processing);GO:0045787(positive regulation of cell cycle);GO:0000184(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay);GO:0019083(viral transcription);GO:0006614(SRP-dependent cotranslational protein targeting to membrane)","03010(Ribosome)","NA","NA","ribosomal protein S15a [Source:HGNC Symbol;Acc:HGNC:10389]",{"v":12.628252,"d":"12.63"},{"v":80.903152,"d":"80.90"},{"v":0.156090976529567,"d":"0.16"},{"v":-2.67954095598487,"d":"-2.68"},{"v":0.000164805336043339,"d":"0.00"},{"v":0.00368514328120201,"d":"0.00"},"down","yes"]
[193304,0,"chr9","+",124869205,124877717,"ENST00000259477",4,1325,"MSTRG.14958","ARPC5L","GO:0005737(cytoplasm);GO:0003779(actin binding);GO:0015629(actin cytoskeleton);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0030833(regulation of actin filament polymerization);GO:0034314(Arp2/3 complex-mediated actin nucleation);GO:0005885(Arp2/3 protein complex);GO:0005925(focal adhesion);GO:0003674(molecular_function);GO:0008150(biological_process);GO:0070062(extracellular exosome);GO:0051015(actin filament binding);GO:0016477(cell migration)","04144(Endocytosis);04810(Regulation of actin cytoskeleton);04666(Fc gamma R-mediated phagocytosis);05130(Pathogenic Escherichia coli infection);05132(Salmonella infection);05131(Shigellosis);05100(Bacterial invasion of epithelial cells)","NA","NA","actin related protein 2/3 complex subunit 5 like [Source:HGNC Symbol;Acc:HGNC:23366]",{"v":11.036817,"d":"11.04"},{"v":1.837522,"d":"1.84"},{"v":6.00635910753722,"d":"6.01"},{"v":2.586490733166,"d":"2.59"},{"v":0.000165102598928378,"d":"0.00"},{"v":3.68766073311168E-3,"d":"0.00"},"up","yes"]
[81050,0,"chr17","+",27631148,27649433,"ENST00000313648",9,1378,"MSTRG.6531","LGALS9","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0030246(carbohydrate binding);GO:0004871(signal transducer activity);GO:0005576(extracellular region);GO:0005615(extracellular space);GO:0002376(immune system process);GO:0006935(chemotaxis);GO:0006954(inflammatory response);GO:0070062(extracellular exosome);GO:0098586(cellular response to virus);GO:0010628(positive regulation of gene expression);GO:0005622(intracellular);GO:0032496(response to lipopolysaccharide);GO:0071346(cellular response to interferon-gamma);GO:0043123(positive regulation of I-kappaB kinase/NF-kappaB signaling);GO:0005534(galactose binding);GO:0019899(enzyme binding);GO:0048030(disaccharide binding);GO:0002519(natural killer cell tolerance induction);GO:0007565(female pregnancy);GO:0010629(negative regulation of gene expression);GO:0032682(negative regulation of chemokine production);GO:0032689(negative regulation of interferon-gamma production);GO:0032720(negative regulation of tumor necrosis factor production);GO:0032753(positive regulation of interleukin-4 production);GO:0032834(positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation involved in immune response);GO:0038066(p38MAPK cascade);GO:0042346(positive regulation of NF-kappaB import into nucleus);GO:0043305(negative regulation of mast cell degranulation);GO:0045953(negative regulation of natural killer cell mediated cytotoxicity);GO:0046007(negative regulation of activated T cell proliferation);GO:0046598(positive regulation of viral entry into host cell);GO:0050718(positive regulation of interleukin-1 beta secretion);GO:0051092(positive regulation of NF-kappaB transcription factor activity);GO:0060135(maternal process involved in female pregnancy);GO:0070241(positive regulation of activated T cell autonomous cell death);GO:0070371(ERK1 and ERK2 cascade);GO:0070374(positive regulation of ERK1 and ERK2 cascade);GO:0070555(response to interleukin-1);GO:0071636(positive regulation of transforming growth factor beta production);GO:0071639(positive regulation of monocyte chemotactic protein-1 production);GO:1902715(positive regulation of interferon-gamma secretion);GO:1904469(positive regulation of tumor necrosis factor secretion);GO:2000484(positive regulation of interleukin-8 secretion);GO:2000510(positive regulation of dendritic cell chemotaxis);GO:2000562(negative regulation of CD4-positive, alpha-beta T cell proliferation);GO:2000563(positive regulation of CD4-positive, alpha-beta T cell proliferation);GO:2000667(positive regulation of interleukin-13 secretion);GO:2000670(positive regulation of dendritic cell apoptotic process);GO:2000778(positive regulation of interleukin-6 secretion);GO:2001181(positive regulation of interleukin-10 secretion);GO:2001184(positive regulation of interleukin-12 secretion);GO:2001190(positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell);GO:2001200(positive regulation of dendritic cell differentiation);GO:2001269(positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway)","NA","NA","NA","galectin 9 [Source:HGNC Symbol;Acc:HGNC:6570]",{"v":4.873583,"d":"4.87"},{"v":0.791981,"d":"0.79"},{"v":6.15366151460704,"d":"6.15"},{"v":2.62144508965325,"d":"2.62"},{"v":0.000165482065874108,"d":"0.00"},{"v":0.00369200658254099,"d":"0.00"},"up","yes"]
[110560,"i","chr2","-",69789545,69798998,"MSTRG.8795.1",2,1103,"MSTRG.8795","ANXA4","NA","NA","NA","NA","NA",{"v":0.858125,"d":"0.86"},{"v":5.776577,"d":"5.78"},{"v":0.148552507826001,"d":"0.15"},{"v":-2.75095513429434,"d":"-2.75"},{"v":1.65790053688213E-4,"d":"0.00"},{"v":0.00369474976790875,"d":"0.00"},"down","yes"]
[50076,0,"chr13","-",45333471,45341284,"ENST00000616577",6,4814,"MSTRG.3983","TPT1","GO:0003723(RNA binding);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005515(protein binding);GO:0006816(calcium ion transport);GO:0005509(calcium ion binding);GO:0070062(extracellular exosome);GO:0008017(microtubule binding);GO:0009615(response to virus);GO:0030154(cell differentiation);GO:0042981(regulation of apoptotic process);GO:0043066(negative regulation of apoptotic process);GO:0005615(extracellular space);GO:0005634(nucleus);GO:0006874(cellular calcium ion homeostasis);GO:0045298(tubulin complex);GO:1902230(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage);GO:0005771(multivesicular body)","NA","NA","NA","tumor protein, translationally-controlled 1 [Source:HGNC Symbol;Acc:HGNC:12022]",{"v":0.173585,"d":"0.17"},{"v":1.198103,"d":"1.20"},{"v":0.144883202863193,"d":"0.14"},{"v":-2.78703775016962,"d":"-2.79"},{"v":1.66146256378821E-4,"d":"0.00"},{"v":0.00369690269782727,"d":"0.00"},"down","yes"]
[72903,"j","chr16","+",50693591,50734248,"MSTRG.5917.1",12,5551,"MSTRG.5917","NOD2","NA","NA","NA","NA","NA",{"v":1.391562,"d":"1.39"},{"v":8.915288,"d":"8.92"},{"v":0.156087161738353,"d":"0.16"},{"v":-2.67957621521472,"d":"-2.68"},{"v":0.000166256942240028,"d":"0.00"},{"v":0.00369690269782727,"d":"0.00"},"down","yes"]
[123202,0,"chr20","-",35302566,35412141,"ENST00000374385",10,2447,"ENSG00000101019","UQCC1","GO:0016020(membrane);GO:0005743(mitochondrial inner membrane);GO:0005739(mitochondrion);GO:0031410(cytoplasmic vesicle);GO:0005515(protein binding);GO:0070131(positive regulation of mitochondrial translation);GO:0034551(mitochondrial respiratory chain complex III assembly)","NA","NA","NA","ubiquinol-cytochrome c reductase complex assembly factor 1 [Source:HGNC Symbol;Acc:HGNC:15891]",{"v":2.624451,"d":"2.62"},{"v":0.423573,"d":"0.42"},{"v":6.19598274677564,"d":"6.20"},{"v":2.63133312682989,"d":"2.63"},{"v":1.66768033922843E-4,"d":"0.00"},{"v":0.00370414249318278,"d":"0.00"},"up","yes"]
[5066,0,"chr1","+",43445252,43452650,"ENST00000460536",10,4286,"MSTRG.491","SZT2","GO:0016020(membrane);GO:0005765(lysosomal membrane);GO:0005764(lysosome);GO:0005777(peroxisome);GO:1904262(negative regulation of TORC1 signaling);GO:0003674(molecular_function);GO:0070062(extracellular exosome);GO:0061700(GATOR2 complex);GO:0042149(cellular response to glucose starvation);GO:0061462(protein localization to lysosome);GO:0034198(cellular response to amino acid starvation);GO:0007417(central nervous system development);GO:0009791(post-embryonic development);GO:1990130(GATOR1 complex);GO:0021540(corpus callosum morphogenesis);GO:1901668(regulation of superoxide dismutase activity);GO:0140007(KICSTOR complex);GO:0031667(response to nutrient levels);GO:0043473(pigmentation)","NA","NA","NA","SZT2, KICSTOR complex subunit [Source:HGNC Symbol;Acc:HGNC:29040]",{"v":1.190473,"d":"1.19"},{"v":0.189617,"d":"0.19"},{"v":6.27830310573419,"d":"6.28"},{"v":2.65037468145007,"d":"2.65"},{"v":1.6716629347823E-4,"d":"0.00"},{"v":0.00370886283130367,"d":"0.00"},"up","yes"]
[102846,0,"chr19","-",45620812,45639401,"ENST00000588000",11,1542,"ENSG00000125746","EML2","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005737(cytoplasm);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0005874(microtubule);GO:0008017(microtubule binding);GO:0005819(spindle);GO:0007601(visual perception);GO:0015631(tubulin binding);GO:0005875(microtubule associated complex);GO:0007605(sensory perception of sound);GO:0072686(mitotic spindle);GO:0010968(regulation of microtubule nucleation);GO:0031115(negative regulation of microtubule polymerization);GO:0005102(receptor binding);GO:0008022(protein C-terminus binding)","NA","NA","NA","echinoderm microtubule associated protein like 2 [Source:HGNC Symbol;Acc:HGNC:18035]",{"v":3.968033,"d":"3.97"},{"v":0.641414,"d":"0.64"},{"v":6.18638352140739,"d":"6.19"},{"v":2.62909627527672,"d":"2.63"},{"v":1.68183780717806E-4,"d":"0.00"},{"v":0.00372729604147963,"d":"0.00"},"up","yes"]
[46318,0,"chr12","-",108778192,108857590,"ENST00000326495",15,13040,"MSTRG.3688","SSH1","GO:0005737(cytoplasm);GO:0016787(hydrolase activity);GO:0003779(actin binding);GO:0004725(protein tyrosine phosphatase activity);GO:0008138(protein tyrosine/serine/threonine phosphatase activity);GO:0016791(phosphatase activity);GO:0006470(protein dephosphorylation);GO:0016311(dephosphorylation);GO:0035335(peptidyl-tyrosine dephosphorylation);GO:0005886(plasma membrane);GO:0004721(phosphoprotein phosphatase activity);GO:0030036(actin cytoskeleton organization);GO:0005856(cytoskeleton);GO:0042995(cell projection);GO:0005515(protein binding);GO:0030496(midbody);GO:0030027(lamellipodium);GO:0032154(cleavage furrow);GO:0050770(regulation of axonogenesis);GO:0000902(cell morphogenesis);GO:0071318(cellular response to ATP);GO:0010591(regulation of lamellipodium assembly);GO:0008064(regulation of actin polymerization or depolymerization);GO:0032268(regulation of cellular protein metabolic process);GO:0031915(positive regulation of synaptic plasticity);GO:0098976(excitatory chemical synaptic transmission);GO:1901216(positive regulation of neuron death);GO:1904719(positive regulation of AMPA glutamate receptor clustering);GO:1904754(positive regulation of vascular associated smooth muscle cell migration);GO:2000463(positive regulation of excitatory postsynaptic potential);GO:0005829(cytosol);GO:0030426(growth cone);GO:0031252(cell leading edge);GO:0016020(membrane);GO:0016021(integral component of membrane)","04810(Regulation of actin cytoskeleton);04360(Axon guidance)","K05766","EC:3.1.3.16;EC:3.1.3.48","slingshot protein phosphatase 1 [Source:HGNC Symbol;Acc:HGNC:30579]",{"v":0.561146,"d":"0.56"},{"v":3.585515,"d":"3.59"},{"v":0.15650359850677,"d":"0.16"},{"v":-2.675732265281,"d":"-2.68"},{"v":0.000168382579449641,"d":"0.00"},{"v":0.0037275646856435,"d":"0.00"},"down","yes"]
[193740,0,"chr9","-",128179051,128191488,"ENST00000488559",6,952,"MSTRG.14997","CIZ1","GO:0005634(nucleus);GO:0003676(nucleic acid binding);GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0005654(nucleoplasm);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0030332(cyclin binding);GO:0032298(positive regulation of DNA-dependent DNA replication initiation);GO:0051457(maintenance of protein location in nucleus)","NA","NA","NA","CDKN1A interacting zinc finger protein 1 [Source:HGNC Symbol;Acc:HGNC:16744]",{"v":5.582733,"d":"5.58"},{"v":0.889047,"d":"0.89"},{"v":6.27945766646758,"d":"6.28"},{"v":2.65063996426273,"d":"2.65"},{"v":0.000170804947279073,"d":"0.00"},{"v":3.77700242222429E-3,"d":"0.00"},"up","yes"]
[167604,0,"chr6","-",85608329,85642991,"ENST00000355238",12,6449,"MSTRG.13153","SYNCRIP","GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0006397(mRNA processing);GO:0008380(RNA splicing);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0030529(intracellular ribonucleoprotein complex);GO:0005783(endoplasmic reticulum);GO:0005515(protein binding);GO:0005681(spliceosomal complex);GO:0005654(nucleoplasm);GO:0043231(intracellular membrane-bounded organelle);GO:0006417(regulation of translation);GO:0071346(cellular response to interferon-gamma);GO:0016032(viral process);GO:0017148(negative regulation of translation);GO:0000398(mRNA splicing, via spliceosome);GO:0006396(RNA processing);GO:0071013(catalytic step 2 spliceosome);GO:0001649(osteoblast differentiation);GO:0070934(CRD-mediated mRNA stabilization);GO:0070937(CRD-mediated mRNA stability complex);GO:0071204(histone pre-mRNA 3'end processing complex);GO:0097452(GAIT complex);GO:0008143(poly(A) binding);GO:0019013(viral nucleocapsid)","NA","NA","NA","synaptotagmin binding cytoplasmic RNA interacting protein [Source:HGNC Symbol;Acc:HGNC:16918]",{"v":0.511328,"d":"0.51"},{"v":3.298573,"d":"3.30"},{"v":0.15501491099333,"d":"0.16"},{"v":-2.68952109886224,"d":"-2.69"},{"v":1.71489377162472E-4,"d":"0.00"},{"v":0.0037851068485365,"d":"0.00"},"down","yes"]
[164485,"j","chr6","+",31615211,31617027,"MSTRG.12862.2",6,772,"MSTRG.12862","AIF1","NA","NA","NA","NA","NA",{"v":6.03216,"d":"6.03"},{"v":0.947949,"d":"0.95"},{"v":6.36338030843431,"d":"6.36"},{"v":2.66979334706443,"d":"2.67"},{"v":1.71550565801559E-4,"d":"0.00"},{"v":0.0037851068485365,"d":"0.00"},"up","yes"]
[176469,0,"chr7","+",99325879,99394653,"ENST00000638617",17,2430,"MSTRG.13793","AC004922.1","GO:0015629(actin cytoskeleton);GO:0030833(regulation of actin filament polymerization);GO:0034314(Arp2/3 complex-mediated actin nucleation);GO:0005885(Arp2/3 protein complex)","NA","NA","NA","NA",{"v":0.367517,"d":"0.37"},{"v":2.485898,"d":"2.49"},{"v":0.147840740046454,"d":"0.15"},{"v":-2.75788421130351,"d":"-2.76"},{"v":0.000172328134042299,"d":"0.00"},{"v":0.00379806642445543,"d":"0.00"},"down","yes"]
[52013,0,"chr13","+",113490995,113550195,"ENST00000434316",13,3050,"MSTRG.4120","TMCO3","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0055085(transmembrane transport);GO:0098655(cation transmembrane transport);GO:0006811(ion transport);GO:0015297(antiporter activity);GO:0015299(solute:proton antiporter activity);GO:0006812(cation transport);GO:1902600(hydrogen ion transmembrane transport);GO:0022890(inorganic cation transmembrane transporter activity)","NA","NA","NA","transmembrane and coiled-coil domains 3 [Source:HGNC Symbol;Acc:HGNC:20329]",{"v":1.129542,"d":"1.13"},{"v":7.282133,"d":"7.28"},{"v":0.155111421337677,"d":"0.16"},{"v":-2.68862317446715,"d":"-2.69"},{"v":0.000174340835329145,"d":"0.00"},{"v":0.00383818941549324,"d":"0.00"},"down","yes"]
[42705,0,"chr12","+",55829608,55836244,"ENST00000478241",5,2924,"MSTRG.3437","TMEM198B","NA","NA","NA","NA","transmembrane protein 198B (pseudogene) [Source:HGNC Symbol;Acc:HGNC:43629]",{"v":1.762058,"d":"1.76"},{"v":0.2841,"d":"0.28"},{"v":6.20224568813798,"d":"6.20"},{"v":2.63279067623073,"d":"2.63"},{"v":0.000176194600766415,"d":"0.00"},{"v":0.00387432975211332,"d":"0.00"},"up","yes"]
[156763,0,"chr5","+",94618347,94697621,"ENST00000265140",21,5905,"ENSG00000133302","SLF1","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0000786(nucleosome);GO:0005856(cytoskeleton);GO:0006281(DNA repair);GO:0006974(cellular response to DNA damage stimulus);GO:0005813(centrosome);GO:0005815(microtubule organizing center);GO:0005515(protein binding);GO:0031625(ubiquitin protein ligase binding);GO:0032403(protein complex binding);GO:0031334(positive regulation of protein complex assembly);GO:0035861(site of double-strand break);GO:0042405(nuclear inclusion body);GO:2000781(positive regulation of double-strand break repair);GO:0034184(positive regulation of maintenance of mitotic sister chromatid cohesion);GO:1990166(protein localization to site of double-strand break)","NA","NA","NA","SMC5-SMC6 complex localization factor 1 [Source:HGNC Symbol;Acc:HGNC:25408]",{"v":0.136304,"d":"0.14"},{"v":0.917816,"d":"0.92"},{"v":0.148509069355949,"d":"0.15"},{"v":-2.75137705668746,"d":"-2.75"},{"v":0.000176370480001553,"d":"0.00"},{"v":0.00387432975211332,"d":"0.00"},"down","yes"]
[4132,0,"chr1","-",34986165,35031711,"ENST00000493328",15,6241,"MSTRG.404","ZMYM6","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0005737(cytoplasm);GO:0000981(RNA polymerase II transcription factor activity, sequence-specific DNA binding);GO:0007010(cytoskeleton organization);GO:0022604(regulation of cell morphogenesis);GO:0005654(nucleoplasm);GO:0003677(DNA binding);GO:0007275(multicellular organism development)","NA","NA","NA","zinc finger MYM-type containing 6 [Source:HGNC Symbol;Acc:HGNC:13050]",{"v":1.50363,"d":"1.50"},{"v":0.249371,"d":"0.25"},{"v":6.02969070180574,"d":"6.03"},{"v":2.59208399973473,"d":"2.59"},{"v":0.000176798878899354,"d":"0.00"},{"v":0.00387899481334184,"d":"0.00"},"up","yes"]
[188005,0,"chr8","-",143580620,143587564,"ENST00000530445",5,1217,"MSTRG.14619","EEF1D","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0006412(translation);GO:0005829(cytosol);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0001650(fibrillar center);GO:0005783(endoplasmic reticulum);GO:0005515(protein binding);GO:0004871(signal transducer activity);GO:0003746(translation elongation factor activity);GO:0006414(translational elongation);GO:0005853(eukaryotic translation elongation factor 1 complex);GO:0007165(signal transduction);GO:0045296(cadherin binding);GO:0043123(positive regulation of I-kappaB kinase/NF-kappaB signaling);GO:0008135(translation factor activity, RNA binding);GO:0071479(cellular response to ionizing radiation)","05168(Herpes simplex infection)","NA","NA","eukaryotic translation elongation factor 1 delta [Source:HGNC Symbol;Acc:HGNC:3211]",{"v":7.825715,"d":"7.83"},{"v":1.294276,"d":"1.29"},{"v":6.04640354916571,"d":"6.05"},{"v":2.59607727055529,"d":"2.60"},{"v":0.000176971367936419,"d":"0.00"},{"v":0.00387899481334184,"d":"0.00"},"up","yes"]
[191180,0,"chr9","+",77177445,77421541,"ENST00000360280",72,15320,"ENSG00000197969","VPS13A","GO:0006810(transport);GO:0015031(protein transport);GO:0005829(cytosol);GO:0005515(protein binding);GO:0005622(intracellular);GO:0006895(Golgi to endosome transport);GO:0008104(protein localization);GO:0006914(autophagy);GO:0007399(nervous system development);GO:0007626(locomotory behavior);GO:0035176(social behavior);GO:0031045(dense core granule)","NA","NA","NA","vacuolar protein sorting 13 homolog A [Source:HGNC Symbol;Acc:HGNC:1908]",{"v":1.12175,"d":"1.12"},{"v":0.189178,"d":"0.19"},{"v":5.92960069352673,"d":"5.93"},{"v":2.56793495521559,"d":"2.57"},{"v":0.000179241110030448,"d":"0.00"},{"v":0.00392443693540349,"d":"0.00"},"up","yes"]
[144739,0,"chr3","-",197044331,197297204,"ENST00000422288",23,2854,"ENSG00000075711","DLG1","GO:0005737(cytoplasm);GO:0005634(nucleus);GO:0016020(membrane);GO:0034220(ion transmembrane transport);GO:0005794(Golgi apparatus);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005886(plasma membrane);GO:0004721(phosphoprotein phosphatase activity);GO:0005515(protein binding);GO:0048471(perinuclear region of cytoplasm);GO:0030054(cell junction);GO:0045202(synapse);GO:0045211(postsynaptic membrane);GO:0005874(microtubule);GO:0006470(protein dephosphorylation);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0005829(cytosol);GO:0045296(cadherin binding);GO:0070062(extracellular exosome);GO:0007399(nervous system development);GO:0019901(protein kinase binding);GO:0042383(sarcolemma);GO:0016323(basolateral plasma membrane);GO:0014069(postsynaptic density);GO:0016032(viral process);GO:0019902(phosphatase binding);GO:0008022(protein C-terminus binding);GO:0046037(GMP metabolic process);GO:0046710(GDP metabolic process);GO:0008360(regulation of cell shape);GO:0015459(potassium channel regulator activity);GO:0044325(ion channel binding);GO:0007268(chemical synaptic transmission);GO:0009898(cytoplasmic side of plasma membrane);GO:0042391(regulation of membrane potential);GO:0005911(cell-cell junction);GO:0007015(actin filament organization);GO:0070373(negative regulation of ERK1 and ERK2 cascade);GO:0045930(negative regulation of mitotic cell cycle);GO:0097016(L27 domain binding);GO:0030866(cortical actin cytoskeleton organization);GO:0004385(guanylate kinase activity);GO:0016337(single organismal cell-cell adhesion);GO:0001772(immunological synapse);GO:0090004(positive regulation of establishment of protein localization to plasma membrane);GO:0007093(mitotic cell cycle checkpoint);GO:0007163(establishment or maintenance of cell polarity);GO:0014704(intercalated disc);GO:0001935(endothelial cell proliferation);GO:0015276(ligand-gated ion channel activity);GO:0072659(protein localization to plasma membrane);GO:0043268(positive regulation of potassium ion transport);GO:0098911(regulation of ventricular cardiac muscle cell action potential);GO:0030953(astral microtubule organization);GO:0034629(cellular protein complex localization);GO:0043622(cortical microtubule organization);GO:0051660(establishment of centrosome localization);GO:1903753(negative regulation of p38MAPK cascade);GO:0005923(bicellular tight junction);GO:1902305(regulation of sodium ion transmembrane transport);GO:0008328(ionotropic glutamate receptor complex);GO:0035255(ionotropic glutamate receptor binding);GO:0045197(establishment or maintenance of epithelial cell apical/basal polarity);GO:0097120(receptor localization to synapse);GO:0008092(cytoskeletal protein binding);GO:0019900(kinase binding);GO:0031434(mitogen-activated protein kinase kinase binding);GO:0032947(protein complex scaffold);GO:0001657(ureteric bud development);GO:0001658(branching involved in ureteric bud morphogenesis);GO:0001771(immunological synapse formation);GO:0002088(lens development in camera-type eye);GO:0002369(T cell cytokine production);GO:0008104(protein localization);GO:0008284(positive regulation of cell proliferation);GO:0030432(peristalsis);GO:0030838(positive regulation of actin filament polymerization);GO:0031579(membrane raft organization);GO:0031641(regulation of myelination);GO:0032147(activation of protein kinase activity);GO:0042110(T cell activation);GO:0042130(negative regulation of T cell proliferation);GO:0042982(amyloid precursor protein metabolic process);GO:0043113(receptor clustering);GO:0048608(reproductive structure development);GO:0048704(embryonic skeletal system morphogenesis);GO:0048729(tissue morphogenesis);GO:0048745(smooth muscle tissue development);GO:0050680(negative regulation of epithelial cell proliferation);GO:0051898(negative regulation of protein kinase B signaling);GO:0060022(hard palate development);GO:0070830(bicellular tight junction assembly);GO:1903286(regulation of potassium ion import);GO:1903760(regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization);GO:1903764(regulation of potassium ion export across plasma membrane);GO:0005605(basal lamina);GO:0016328(lateral plasma membrane);GO:0031253(cell projection membrane);GO:0031594(neuromuscular junction);GO:0033268(node of Ranvier);GO:0035748(myelin sheath abaxonal region);GO:0043219(lateral loop);GO:0045121(membrane raft);GO:0097025(MPP7-DLG1-LIN7 complex)","04390(Hippo signaling pathway);04530(Tight junction);04660(T cell receptor signaling pathway);05203(Viral carcinogenesis);05166(HTLV-I infection);05165(Human papillomavirus infection)","K12076","NA","discs large MAGUK scaffold protein 1 [Source:HGNC Symbol;Acc:HGNC:2900]",{"v":4.633907,"d":"4.63"},{"v":0.778864,"d":"0.78"},{"v":5.94957142710409,"d":"5.95"},{"v":2.57278574871294,"d":"2.57"},{"v":1.80152686392402E-4,"d":"0.00"},{"v":0.00394007540184391,"d":"0.00"},"up","yes"]
[58049,"j","chr14","+",94110747,94116696,"MSTRG.4637.8",4,489,"MSTRG.4637","IFI27","NA","NA","NA","NA","NA",{"v":24.392296,"d":"24.39"},{"v":4.097781,"d":"4.10"},{"v":5.9525621305775,"d":"5.95"},{"v":2.57351077387583,"d":"2.57"},{"v":0.000180600096433491,"d":"0.00"},{"v":0.00394285593468805,"d":"0.00"},"up","yes"]
[2010,0,"chr1","+",16367265,16398142,"ENST00000492354",3,3401,"MSTRG.187","SZRD1","NA","NA","NA","NA","SUZ RNA binding domain containing 1 [Source:HGNC Symbol;Acc:HGNC:30232]",{"v":1.387565,"d":"1.39"},{"v":8.841096,"d":"8.84"},{"v":0.156944908187854,"d":"0.16"},{"v":-2.67166987100903,"d":"-2.67"},{"v":0.000180674738593728,"d":"0.00"},{"v":0.00394285593468805,"d":"0.00"},"down","yes"]
[70194,0,"chr16","-",18782956,18790383,"ENST00000563390",5,525,"MSTRG.5711","RPS15A","GO:0003723(RNA binding);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0006412(translation);GO:0030529(intracellular ribonucleoprotein complex);GO:0003735(structural constituent of ribosome);GO:0005840(ribosome);GO:0022627(cytosolic small ribosomal subunit);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0009615(response to virus);GO:0031012(extracellular matrix);GO:0005739(mitochondrion);GO:0005515(protein binding);GO:0008284(positive regulation of cell proliferation);GO:0006413(translational initiation);GO:0006364(rRNA processing);GO:0045787(positive regulation of cell cycle);GO:0000184(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay);GO:0019083(viral transcription);GO:0006614(SRP-dependent cotranslational protein targeting to membrane)","03010(Ribosome)","K02957","NA","ribosomal protein S15a [Source:HGNC Symbol;Acc:HGNC:10389]",{"v":506.597656,"d":"506.60"},{"v":87.556114,"d":"87.56"},{"v":5.78597693360397,"d":"5.79"},{"v":2.53256057182585,"d":"2.53"},{"v":0.000184922314093682,"d":"0.00"},{"v":0.00403114494303783,"d":"0.00"},"up","yes"]
[108562,0,"chr2","+",32165864,32224379,"ENST00000282587",14,5089,"ENSG00000152683","SLC30A6","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0055085(transmembrane transport);GO:0098655(cation transmembrane transport);GO:0006812(cation transport);GO:0008324(cation transmembrane transporter activity);GO:0006810(transport);GO:0005794(Golgi apparatus);GO:0006811(ion transport);GO:0071577(zinc II ion transmembrane transport);GO:0005385(zinc ion transmembrane transporter activity);GO:0000139(Golgi membrane);GO:0006829(zinc II ion transport);GO:0010043(response to zinc ion);GO:0061088(regulation of sequestering of zinc ion)","NA","NA","NA","solute carrier family 30 member 6 [Source:HGNC Symbol;Acc:HGNC:19305]",{"v":2.069305,"d":"2.07"},{"v":0.345548,"d":"0.35"},{"v":5.98847338141155,"d":"5.99"},{"v":2.58218826916206,"d":"2.58"},{"v":1.85680964895544E-4,"d":"0.00"},{"v":0.00404326881901223,"d":"0.00"},"up","yes"]
[179522,0,"chr7","+",142626649,142627399,"ENST00000390394",2,413,"MSTRG.14100","TRBV20-1","NA","NA","NA","NA","T-cell receptor beta variable 20-1 [Source:HGNC Symbol;Acc:HGNC:12196]",{"v":14.451065,"d":"14.45"},{"v":2.366255,"d":"2.37"},{"v":6.10714610217411,"d":"6.11"},{"v":2.61049835940431,"d":"2.61"},{"v":1.86000818661522E-4,"d":"0.00"},{"v":0.0040458217287944,"d":"0.00"},"up","yes"]
[7000,0,"chr1","+",66924959,66985684,"ENST00000401041",14,2552,"MSTRG.627","MIER1","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005654(nucleoplasm);GO:0004407(histone deacetylase activity);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0007165(signal transduction);GO:0004871(signal transducer activity);GO:0005515(protein binding);GO:0017053(transcriptional repressor complex);GO:0043234(protein complex);GO:0043123(positive regulation of I-kappaB kinase/NF-kappaB signaling);GO:0042826(histone deacetylase binding);GO:0016575(histone deacetylation);GO:0031937(positive regulation of chromatin silencing)","NA","NA","NA","MIER1 transcriptional regulator [Source:HGNC Symbol;Acc:HGNC:29657]",{"v":0.42954,"d":"0.43"},{"v":2.836523,"d":"2.84"},{"v":0.151431876279515,"d":"0.15"},{"v":-2.72325917153302,"d":"-2.72"},{"v":1.86446365149467E-4,"d":"0.00"},{"v":0.00405110012981998,"d":"0.00"},"down","yes"]
[177972,0,"chr7","-",115935148,116030741,"ENST00000265440",8,6628,"ENSG00000105967","TFEC","GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0046983(protein dimerization activity);GO:0006355(regulation of transcription, DNA-templated);GO:0006366(transcription from RNA polymerase II promoter);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0005515(protein binding);GO:1903507(negative regulation of nucleic acid-templated transcription);GO:0003713(transcription coactivator activity);GO:0003714(transcription corepressor activity);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:0001077(transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0034605(cellular response to heat);GO:0045944(positive regulation of transcription from RNA polymerase II promoter)","NA","NA","NA","transcription factor EC [Source:HGNC Symbol;Acc:HGNC:11754]",{"v":0.18588,"d":"0.19"},{"v":1.21543,"d":"1.22"},{"v":0.152933529697309,"d":"0.15"},{"v":-2.70902335185841,"d":"-2.71"},{"v":1.86698176703948E-4,"d":"0.00"},{"v":0.00405216216567874,"d":"0.00"},"down","yes"]
[106,"j","chr1","-",726126,740555,"MSTRG.36.16",8,4610,"MSTRG.36","AL669831.1","NA","NA","NA","NA","NA",{"v":3.749699,"d":"3.75"},{"v":0.636885,"d":"0.64"},{"v":5.88756054860768,"d":"5.89"},{"v":2.55766999170663,"d":"2.56"},{"v":0.000187735360902527,"d":"0.00"},{"v":0.00406603943228625,"d":"0.00"},"up","yes"]
[180086,0,"chr7","+",150685700,150693641,"ENST00000223293",3,1449,"MSTRG.14127","GIMAP2","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005525(GTP binding);GO:0000166(nucleotide binding);GO:0005811(lipid particle)","NA","NA","NA","GTPase, IMAP family member 2 [Source:HGNC Symbol;Acc:HGNC:21789]",{"v":14.637917,"d":"14.64"},{"v":2.496234,"d":"2.50"},{"v":5.86400033009726,"d":"5.86"},{"v":2.55188518468415,"d":"2.55"},{"v":0.000187862017509591,"d":"0.00"},{"v":0.00406603943228625,"d":"0.00"},"up","yes"]
[129268,0,"chr22","+",22906342,22906803,"ENST00000390325",1,462,"MSTRG.10249","IGLC3","GO:0016020(membrane);GO:0005886(plasma membrane);GO:0005576(extracellular region);GO:0005615(extracellular space);GO:0002376(immune system process);GO:0003823(antigen binding);GO:0002250(adaptive immune response);GO:0070062(extracellular exosome);GO:0072562(blood microparticle)","NA","NA","NA","immunoglobulin lambda constant 3 (Kern-Oz+ marker) [Source:HGNC Symbol;Acc:HGNC:5857]",{"v":54.834709,"d":"54.83"},{"v":9.37999,"d":"9.38"},{"v":5.84592403616635,"d":"5.85"},{"v":2.54743108241832,"d":"2.55"},{"v":0.00018794843729969,"d":"0.00"},{"v":0.00406603943228625,"d":"0.00"},"up","yes"]
[196708,0,"chrX","-",46599252,46759172,"ENST00000616978",17,10024,"ENSG00000065923","SLC9A7","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0043231(intracellular membrane-bounded organelle);GO:0055085(transmembrane transport);GO:0005794(Golgi apparatus);GO:0042803(protein homodimerization activity);GO:0006811(ion transport);GO:0006813(potassium ion transport);GO:0015297(antiporter activity);GO:0015299(solute:proton antiporter activity);GO:0015385(sodium:proton antiporter activity);GO:0006812(cation transport);GO:0006814(sodium ion transport);GO:0006885(regulation of pH);GO:0035725(sodium ion transmembrane transport);GO:1902600(hydrogen ion transmembrane transport);GO:0071805(potassium ion transmembrane transport);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0005768(endosome);GO:0005802(trans-Golgi network);GO:0055038(recycling endosome membrane);GO:0000139(Golgi membrane);GO:0051453(regulation of intracellular pH);GO:0098719(sodium ion import across plasma membrane);GO:0015386(potassium:proton antiporter activity)","NA","NA","NA","solute carrier family 9 member A7 [Source:HGNC Symbol;Acc:HGNC:17123]",{"v":0.543737,"d":"0.54"},{"v":0.088751,"d":"0.09"},{"v":6.12654505301349,"d":"6.13"},{"v":2.61507372317253,"d":"2.62"},{"v":0.00018869143235066,"d":"0.00"},{"v":0.00407477985112116,"d":"0.00"},"up","yes"]
[196290,0,"chrX","-",30834621,30871802,"ENST00000467136",8,7987,"MSTRG.15210","TAB3","GO:0046872(metal ion binding);GO:0005515(protein binding);GO:0038095(Fc-epsilon receptor signaling pathway);GO:0005886(plasma membrane);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0010008(endosome membrane);GO:0002223(stimulatory C-type lectin receptor signaling pathway);GO:0010507(negative regulation of autophagy);GO:0002755(MyD88-dependent toll-like receptor signaling pathway);GO:0007249(I-kappaB kinase/NF-kappaB signaling);GO:0007254(JNK cascade);GO:0051092(positive regulation of NF-kappaB transcription factor activity);GO:0070423(nucleotide-binding oligomerization domain containing signaling pathway);GO:0000187(activation of MAPK activity)","04064(NF-kappa B signaling pathway);04668(TNF signaling pathway);04621(NOD-like receptor signaling pathway);04657(IL-17 signaling pathway)","K12793","NA","TGF-beta activated kinase 1 and MAP3K7 binding protein 3 [Source:HGNC Symbol;Acc:HGNC:30681]",{"v":0.264932,"d":"0.26"},{"v":1.702462,"d":"1.70"},{"v":0.155616982934127,"d":"0.16"},{"v":-2.68392858046395,"d":"-2.68"},{"v":0.000188760585050435,"d":"0.00"},{"v":0.00407477985112116,"d":"0.00"},"down","yes"]
[141177,0,"chr3","+",141387812,141449792,"ENST00000514251",4,7683,"ENSG00000177311","ZBTB38","GO:0003676(nucleic acid binding);GO:0005654(nucleoplasm);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0005694(chromosome);GO:0042803(protein homodimerization activity);GO:0006974(cellular response to DNA damage stimulus);GO:0005515(protein binding);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0072562(blood microparticle);GO:0045892(negative regulation of transcription, DNA-templated);GO:0008327(methyl-CpG binding);GO:0006275(regulation of DNA replication)","NA","NA","NA","zinc finger and BTB domain containing 38 [Source:HGNC Symbol;Acc:HGNC:26636]",{"v":3.449975,"d":"3.45"},{"v":0.591458,"d":"0.59"},{"v":5.83300082169824,"d":"5.83"},{"v":2.54423827738499,"d":"2.54"},{"v":0.000189848714182728,"d":"0.00"},{"v":0.00409384354730098,"d":"0.00"},"up","yes"]
[182686,0,"chr8","-",30063012,30083207,"ENST00000256255",6,2154,"MSTRG.14272","SARAF","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0006811(ion transport);GO:0006816(calcium ion transport);GO:0030176(integral component of endoplasmic reticulum membrane);GO:0005515(protein binding);GO:2001256(regulation of store-operated calcium entry)","NA","NA","NA","store-operated calcium entry associated regulatory factor [Source:HGNC Symbol;Acc:HGNC:28789]",{"v":7.111086,"d":"7.11"},{"v":44.463215,"d":"44.46"},{"v":0.159931889765506,"d":"0.16"},{"v":-2.64447045988762,"d":"-2.64"},{"v":1.90449554460329E-4,"d":"0.00"},{"v":0.0041023696908995,"d":"0.00"},"down","yes"]
[96509,0,"chr19","+",10654304,10689847,"ENST00000587928",20,4230,"MSTRG.7805","ILF3","GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005730(nucleolus);GO:0005654(nucleoplasm);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0005739(mitochondrion);GO:0003677(DNA binding);GO:0030529(intracellular ribonucleoprotein complex);GO:0005515(protein binding);GO:0003725(double-stranded RNA binding);GO:0045893(positive regulation of transcription, DNA-templated);GO:0051607(defense response to virus);GO:0045071(negative regulation of viral genome replication);GO:0017148(negative regulation of translation);GO:0045892(negative regulation of transcription, DNA-templated);GO:0006468(protein phosphorylation)","NA","NA","NA","interleukin enhancer binding factor 3 [Source:HGNC Symbol;Acc:HGNC:6038]",{"v":2.125413,"d":"2.13"},{"v":0.355312,"d":"0.36"},{"v":5.98182161030306,"d":"5.98"},{"v":2.5805848870924,"d":"2.58"},{"v":0.000192534067764965,"d":"0.00"},{"v":0.0041423822039688,"d":"0.00"},"up","yes"]
[101850,0,"chr19","-",41431318,41439910,"ENST00000438807",4,1454,"MSTRG.8168","DMAC2","GO:0032981(mitochondrial respiratory chain complex I assembly);GO:0005747(mitochondrial respiratory chain complex I);GO:0005739(mitochondrion)","NA","NA","NA","distal membrane arm assembly complex 2 [Source:HGNC Symbol;Acc:HGNC:25496]",{"v":5.891359,"d":"5.89"},{"v":0.981216,"d":"0.98"},{"v":6.0041407804194,"d":"6.00"},{"v":2.58595780454551,"d":"2.59"},{"v":1.92722008588092E-4,"d":"0.00"},{"v":0.0041423822039688,"d":"0.00"},"up","yes"]
[200369,0,"chrX","-",139726349,139832288,"ENST00000327569",30,6115,"ENSG00000101974","ATP11C","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0000287(magnesium ion binding);GO:0016787(hydrolase activity);GO:0004012(phospholipid-translocating ATPase activity);GO:0015914(phospholipid transport);GO:0045332(phospholipid translocation);GO:0006810(transport);GO:0046872(metal ion binding);GO:0005765(lysosomal membrane);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005886(plasma membrane);GO:0006869(lipid transport);GO:0005515(protein binding);GO:0034220(ion transmembrane transport);GO:0055037(recycling endosome);GO:0002329(pre-B cell differentiation);GO:0045579(positive regulation of B cell differentiation)","NA","NA","NA","ATPase phospholipid transporting 11C [Source:HGNC Symbol;Acc:HGNC:13554]",{"v":0.17381,"d":"0.17"},{"v":1.143012,"d":"1.14"},{"v":0.152063145443792,"d":"0.15"},{"v":-2.71725755607988,"d":"-2.72"},{"v":1.93771781895152E-4,"d":"0.00"},{"v":0.00416046767836818,"d":"0.00"},"down","yes"]
[88533,0,"chr17","-",76734123,76737308,"ENST00000585202",4,1359,"MSTRG.7260","SRSF2","GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0006397(mRNA processing);GO:0008380(RNA splicing);GO:0005634(nucleus);GO:0016607(nuclear speck);GO:0005829(cytosol);GO:0005515(protein binding);GO:0005080(protein kinase C binding);GO:0036002(pre-mRNA binding);GO:0000278(mitotic cell cycle);GO:0000381(regulation of alternative mRNA splicing, via spliceosome);GO:0033197(response to vitamin E);GO:0043484(regulation of RNA splicing);GO:0005681(spliceosomal complex);GO:0035061(interchromatin granule);GO:0005654(nucleoplasm);GO:1903507(negative regulation of nucleic acid-templated transcription);GO:0003714(transcription corepressor activity);GO:0070062(extracellular exosome);GO:0006369(termination of RNA polymerase II transcription);GO:0006405(RNA export from nucleus);GO:0031124(mRNA 3'-end processing);GO:0000398(mRNA splicing, via spliceosome);GO:0006406(mRNA export from nucleus)","03040(Spliceosome);05168(Herpes simplex infection)","NA","NA","serine and arginine rich splicing factor 2 [Source:HGNC Symbol;Acc:HGNC:10783]",{"v":4.472103,"d":"4.47"},{"v":0.733992,"d":"0.73"},{"v":6.09284978582873,"d":"6.09"},{"v":2.60711717234088,"d":"2.61"},{"v":0.000194258834944397,"d":"0.00"},{"v":0.00416644513015008,"d":"0.00"},"up","yes"]
[1656,0,"chr1","+",11980312,12013508,"ENST00000235329",19,4539,"MSTRG.164","MFN2","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005525(GTP binding);GO:0000166(nucleotide binding);GO:0016787(hydrolase activity);GO:0003924(GTPase activity);GO:0005829(cytosol);GO:0005741(mitochondrial outer membrane);GO:0005739(mitochondrion);GO:0005515(protein binding);GO:0006915(apoptotic process);GO:0006914(autophagy);GO:0008053(mitochondrial fusion);GO:0006986(response to unfolded protein);GO:0031625(ubiquitin protein ligase binding);GO:0006626(protein targeting to mitochondrion);GO:0007596(blood coagulation);GO:0016236(macroautophagy);GO:0061734(parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization);GO:0001825(blastocyst formation);GO:0007006(mitochondrial membrane organization);GO:0034497(protein localization to pre-autophagosomal structure);GO:0046580(negative regulation of Ras protein signal transduction);GO:0048593(camera-type eye morphogenesis);GO:0048662(negative regulation of smooth muscle cell proliferation);GO:0051646(mitochondrion localization);GO:0015630(microtubule cytoskeleton);GO:0031306(intrinsic component of mitochondrial outer membrane)","04137(Mitophagy - animal);04621(NOD-like receptor signaling pathway)","K06030","EC:3.6.5.-","mitofusin 2 [Source:HGNC Symbol;Acc:HGNC:16877]",{"v":0.747805,"d":"0.75"},{"v":4.738532,"d":"4.74"},{"v":0.157813643550365,"d":"0.16"},{"v":-2.66370615803045,"d":"-2.66"},{"v":0.000195162851011803,"d":"0.00"},{"v":0.00418134314270781,"d":"0.00"},"down","yes"]
[83387,0,"chr17","-",41867574,41919022,"ENST00000393896",28,3682,"MSTRG.6812","ACLY","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0016740(transferase activity);GO:0003824(catalytic activity);GO:0016829(lyase activity);GO:0006629(lipid metabolic process);GO:0008152(metabolic process);GO:0005886(plasma membrane);GO:0003878(ATP citrate synthase activity);GO:0046912(transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer);GO:0048037(cofactor binding);GO:0006085(acetyl-CoA biosynthetic process);GO:0006101(citrate metabolic process);GO:0005576(extracellular region);GO:0005515(protein binding);GO:0070062(extracellular exosome);GO:0043312(neutrophil degranulation);GO:1904813(ficolin-1-rich granule lumen);GO:0035578(azurophil granule lumen);GO:0031325(positive regulation of cellular metabolic process);GO:0046949(fatty-acyl-CoA biosynthetic process);GO:0006633(fatty acid biosynthetic process);GO:0006107(oxaloacetate metabolic process);GO:0006695(cholesterol biosynthetic process);GO:0008610(lipid biosynthetic process);GO:0009346(citrate lyase complex)","00020(Citrate cycle (TCA cycle))","NA","NA","ATP citrate lyase [Source:HGNC Symbol;Acc:HGNC:115]",{"v":10.359365,"d":"10.36"},{"v":1.787948,"d":"1.79"},{"v":5.79399680527622,"d":"5.79"},{"v":2.53455888912792,"d":"2.53"},{"v":0.000196043211443791,"d":"0.00"},{"v":0.00419570294331149,"d":"0.00"},"up","yes"]
[137054,0,"chr3","+",52455508,52493071,"ENST00000345716",21,5238,"MSTRG.10987","NISCH","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0006915(apoptotic process);GO:0035091(phosphatidylinositol binding);GO:0042802(identical protein binding);GO:0005768(endosome);GO:0005769(early endosome);GO:0055037(recycling endosome);GO:0005829(cytosol);GO:0005178(integrin binding);GO:0006006(glucose metabolic process);GO:0008217(regulation of blood pressure);GO:0016601(Rac protein signal transduction);GO:0030036(actin cytoskeleton organization);GO:0030336(negative regulation of cell migration);GO:0032228(regulation of synaptic transmission, GABAergic);GO:0048243(norepinephrine secretion)","NA","NA","NA","nischarin [Source:HGNC Symbol;Acc:HGNC:18006]",{"v":1.00311,"d":"1.00"},{"v":6.295935,"d":"6.30"},{"v":0.159326613124183,"d":"0.16"},{"v":-2.64994082729923,"d":"-2.65"},{"v":1.96550443816444E-4,"d":"0.00"},{"v":0.00420205488450402,"d":"0.00"},"down","yes"]
[59524,0,"chr14","-",105854220,105856218,"ENST00000390559",4,1485,"MSTRG.4749","IGHM","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0005615(extracellular space);GO:0002376(immune system process);GO:0045087(innate immune response);GO:0003823(antigen binding);GO:0002250(adaptive immune response);GO:0050900(leukocyte migration);GO:0006910(phagocytosis, recognition);GO:0006911(phagocytosis, engulfment);GO:0006958(complement activation, classical pathway);GO:0050853(B cell receptor signaling pathway);GO:0050871(positive regulation of B cell activation);GO:0009897(external side of plasma membrane);GO:0031210(phosphatidylcholine binding);GO:0070062(extracellular exosome);GO:0050829(defense response to Gram-negative bacterium);GO:0072562(blood microparticle);GO:0019731(antibacterial humoral response);GO:0009986(cell surface);GO:0003697(single-stranded DNA binding);GO:0042834(peptidoglycan binding);GO:0034987(immunoglobulin receptor binding);GO:0071756(pentameric IgM immunoglobulin complex);GO:0071757(hexameric IgM immunoglobulin complex)","NA","NA","NA","immunoglobulin heavy constant mu [Source:HGNC Symbol;Acc:HGNC:5541]",{"v":34.314877,"d":"34.31"},{"v":5.949058,"d":"5.95"},{"v":5.76811942327676,"d":"5.77"},{"v":2.52810103447915,"d":"2.53"},{"v":0.000198468590092637,"d":"0.00"},{"v":0.00423852492724041,"d":"0.00"},"up","yes"]
[167766,"j","chr6","-",89329659,89352848,"MSTRG.13161.2",7,1136,"MSTRG.13161","UBE2J1","NA","NA","NA","NA","NA",{"v":0.652865,"d":"0.65"},{"v":4.36768,"d":"4.37"},{"v":0.149476381053557,"d":"0.15"},{"v":-2.74201055446983,"d":"-2.74"},{"v":1.9912332268716E-4,"d":"0.00"},{"v":0.00424796421732607,"d":"0.00"},"down","yes"]
[88409,0,"chr17","-",76395358,76453141,"ENST00000586409",14,3579,"ENSG00000175931","UBE2O","GO:0003723(RNA binding);GO:0006810(transport);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0016740(transferase activity);GO:0016567(protein ubiquitination);GO:0005515(protein binding);GO:0016604(nuclear body);GO:0031625(ubiquitin protein ligase binding);GO:0061631(ubiquitin conjugating enzyme activity);GO:0042147(retrograde transport, endosome to Golgi);GO:0004842(ubiquitin-protein transferase activity);GO:0070534(protein K63-linked ubiquitination);GO:0061630(ubiquitin protein ligase activity);GO:0006513(protein monoubiquitination);GO:0030513(positive regulation of BMP signaling pathway)","04120(Ubiquitin mediated proteolysis)","NA","NA","ubiquitin conjugating enzyme E2 O [Source:HGNC Symbol;Acc:HGNC:29554]",{"v":1.235891,"d":"1.24"},{"v":0.199064,"d":"0.20"},{"v":6.20851083068762,"d":"6.21"},{"v":2.63424726605922,"d":"2.63"},{"v":0.000199870176648852,"d":"0.00"},{"v":0.00425934651795548,"d":"0.00"},"up","yes"]
[103815,0,"chr19","+",49335427,49340205,"ENST00000535669",7,1674,"MSTRG.8307","CD37","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005515(protein binding);GO:0005887(integral component of plasma membrane);GO:0070062(extracellular exosome);GO:0007166(cell surface receptor signaling pathway);GO:0001772(immunological synapse)","04640(Hematopoietic cell lineage)","NA","NA","CD37 molecule [Source:HGNC Symbol;Acc:HGNC:1666]",{"v":5.048782,"d":"5.05"},{"v":31.436871,"d":"31.44"},{"v":0.160600652654013,"d":"0.16"},{"v":-2.63845033915048,"d":"-2.64"},{"v":0.000203747121038197,"d":"0.00"},{"v":0.00433733743378541,"d":"0.00"},"down","yes"]
[24283,0,"chr10","-",125836340,125881315,"ENST00000284690",11,3070,"MSTRG.2041","DHX32","GO:0004386(helicase activity);GO:0005634(nucleus);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0016787(hydrolase activity);GO:0005739(mitochondrion);GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0003723(RNA binding);GO:0004004(ATP-dependent RNA helicase activity);GO:0000398(mRNA splicing, via spliceosome);GO:0005681(spliceosomal complex)","NA","NA","NA","DEAH-box helicase 32 (putative) [Source:HGNC Symbol;Acc:HGNC:16717]",{"v":1.390257,"d":"1.39"},{"v":0.223551,"d":"0.22"},{"v":6.21897016788115,"d":"6.22"},{"v":2.63667569664217,"d":"2.64"},{"v":2.04305019484272E-4,"d":"0.00"},{"v":0.0043445821395761,"d":"0.00"},"up","yes"]
[32674,0,"chr11","-",72097348,72103236,"ENST00000538404",4,1346,"MSTRG.2669","LAMTOR1","GO:0045121(membrane raft);GO:0032008(positive regulation of TOR signaling);GO:0071230(cellular response to amino acid stimulus);GO:0071986(Ragulator complex);GO:0007040(lysosome organization);GO:0031902(late endosome membrane);GO:0001919(regulation of receptor recycling);GO:0032439(endosome localization);GO:0042632(cholesterol homeostasis);GO:0043410(positive regulation of MAPK cascade);GO:0016020(membrane);GO:0005765(lysosomal membrane);GO:0005886(plasma membrane);GO:0043547(positive regulation of GTPase activity);GO:0005515(protein binding);GO:0005764(lysosome);GO:0005085(guanyl-nucleotide exchange factor activity);GO:0005768(endosome);GO:0070062(extracellular exosome);GO:0043312(neutrophil degranulation);GO:0035579(specific granule membrane);GO:0035577(azurophil granule membrane);GO:0016049(cell growth);GO:0101003(ficolin-1-rich granule membrane);GO:0032947(protein complex scaffold);GO:0007050(cell cycle arrest);GO:0016241(regulation of macroautophagy);GO:0007032(endosome organization);GO:0032418(lysosome localization);GO:0034613(cellular protein localization);GO:0051020(GTPase binding);GO:0010872(regulation of cholesterol esterification);GO:0010874(regulation of cholesterol efflux);GO:0060620(regulation of cholesterol import)","04150(mTOR signaling pathway)","NA","NA","late endosomal/lysosomal adaptor, MAPK and MTOR activator 1 [Source:HGNC Symbol;Acc:HGNC:26068]",{"v":3.954272,"d":"3.95"},{"v":0.648241,"d":"0.65"},{"v":6.10000293100868,"d":"6.10"},{"v":2.60880993588055,"d":"2.61"},{"v":0.000204676748906227,"d":"0.00"},{"v":0.00434785672570163,"d":"0.00"},"up","yes"]
[24364,0,"chr10","-",128096659,128126385,"ENST00000368654",15,12678,"ENSG00000148773","MKI67","GO:0003723(RNA binding);GO:0005634(nucleus);GO:0016020(membrane);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0005730(nucleolus);GO:0003677(DNA binding);GO:0005694(chromosome);GO:0005515(protein binding);GO:0007049(cell cycle);GO:0016604(nuclear body);GO:0008283(cell proliferation);GO:0008022(protein C-terminus binding);GO:0007088(regulation of mitotic nuclear division);GO:0051983(regulation of chromosome segregation);GO:0000793(condensed chromosome);GO:1902275(regulation of chromatin organization);GO:0006259(DNA metabolic process);GO:0014070(response to organic cyclic compound);GO:0030212(hyaluronan metabolic process);GO:0031100(animal organ regeneration);GO:0034605(cellular response to heat);GO:0051321(meiotic cell cycle);GO:0000775(chromosome, centromeric region);GO:0005737(cytoplasm)","NA","NA","NA","marker of proliferation Ki-67 [Source:HGNC Symbol;Acc:HGNC:7107]",{"v":1.875052,"d":"1.88"},{"v":0.323895,"d":"0.32"},{"v":5.7890736195372,"d":"5.79"},{"v":2.53333250340837,"d":"2.53"},{"v":0.000205253835707523,"d":"0.00"},{"v":0.00435203836257732,"d":"0.00"},"up","yes"]
[23469,0,"chr10","+",110871795,110900005,"ENST00000393104",13,3697,"MSTRG.1979","PDCD4","GO:1900016(negative regulation of cytokine production involved in inflammatory response);GO:1905064(negative regulation of vascular smooth muscle cell differentiation);GO:0005634(nucleus);GO:0050729(positive regulation of inflammatory response);GO:0030509(BMP signaling pathway);GO:0060940(epithelial to mesenchymal transition involved in cardiac fibroblast development);GO:0071222(cellular response to lipopolysaccharide);GO:2000353(positive regulation of endothelial cell apoptotic process);GO:0003723(RNA binding);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005515(protein binding);GO:0006915(apoptotic process);GO:0035722(interleukin-12-mediated signaling pathway);GO:0045786(negative regulation of cell cycle);GO:0045892(negative regulation of transcription, DNA-templated);GO:0007569(cell aging);GO:0043508(negative regulation of JUN kinase activity);GO:0034393(positive regulation of smooth muscle cell apoptotic process);GO:0043066(negative regulation of apoptotic process);GO:0051246(regulation of protein metabolic process);GO:1901224(positive regulation of NIK/NF-kappaB signaling);GO:1904761(negative regulation of myofibroblast differentiation)","05206(MicroRNAs in cancer);05205(Proteoglycans in cancer)","K16865","NA","programmed cell death 4 [Source:HGNC Symbol;Acc:HGNC:8763]",{"v":2.808855,"d":"2.81"},{"v":0.477368,"d":"0.48"},{"v":5.88404543245463,"d":"5.88"},{"v":2.55680838611075,"d":"2.56"},{"v":2.05309502080721E-4,"d":"0.00"},{"v":0.00435203836257732,"d":"0.00"},"up","yes"]
[30675,0,"chr11","+",64230758,64234281,"ENST00000321460",5,1015,"MSTRG.2511","DNAJC4","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005515(protein binding);GO:0006457(protein folding);GO:0051082(unfolded protein binding);GO:0006986(response to unfolded protein);GO:0005739(mitochondrion)","NA","NA","NA","DnaJ heat shock protein family (Hsp40) member C4 [Source:HGNC Symbol;Acc:HGNC:5271]",{"v":11.077991,"d":"11.08"},{"v":1.886576,"d":"1.89"},{"v":5.87200886685721,"d":"5.87"},{"v":2.5538541466827,"d":"2.55"},{"v":0.000205600653169836,"d":"0.00"},{"v":4.35358838016467E-3,"d":"0.00"},"up","yes"]
[158988,0,"chr5","-",139387569,139389883,"ENST00000503120",3,1887,"MSTRG.12358","MZB1","GO:0005737(cytoplasm);GO:0005783(endoplasmic reticulum);GO:0005576(extracellular region);GO:0006915(apoptotic process);GO:0005788(endoplasmic reticulum lumen);GO:0042127(regulation of cell proliferation);GO:0033622(integrin activation);GO:0034663(endoplasmic reticulum chaperone complex);GO:0002642(positive regulation of immunoglobulin biosynthetic process);GO:0030888(regulation of B cell proliferation);GO:2001274(negative regulation of glucose import in response to insulin stimulus);GO:0008284(positive regulation of cell proliferation)","NA","NA","NA","marginal zone B and B1 cell specific protein [Source:HGNC Symbol;Acc:HGNC:30125]",{"v":2.96464,"d":"2.96"},{"v":0.484358,"d":"0.48"},{"v":6.12076191577304,"d":"6.12"},{"v":2.61371125155996,"d":"2.61"},{"v":2.07079416141643E-4,"d":"0.00"},{"v":0.00437646210243101,"d":"0.00"},"up","yes"]
[85663,0,"chr17","+",50719599,50751617,"ENST00000393227",11,2284,"MSTRG.7029","LUC7L3","GO:0003723(RNA binding);GO:0003729(mRNA binding);GO:0006397(mRNA processing);GO:0008380(RNA splicing);GO:0005634(nucleus);GO:0016607(nuclear speck);GO:0005654(nucleoplasm);GO:0003677(DNA binding);GO:0005685(U1 snRNP);GO:0006376(mRNA splice site selection);GO:0005515(protein binding);GO:0071004(U2-type prespliceosome)","NA","NA","NA","LUC7 like 3 pre-mRNA splicing factor [Source:HGNC Symbol;Acc:HGNC:24309]",{"v":5.348923,"d":"5.35"},{"v":0.911094,"d":"0.91"},{"v":5.87087940432052,"d":"5.87"},{"v":2.55357662211329,"d":"2.55"},{"v":0.000207119225100025,"d":"0.00"},{"v":0.00437646210243101,"d":"0.00"},"up","yes"]
[138069,0,"chr3","-",71771656,71785206,"ENST00000353065",3,1549,"MSTRG.11047","PROK2","GO:0005623(cell);GO:0005576(extracellular region);GO:0048511(rhythmic process);GO:0007186(G-protein coupled receptor signaling pathway);GO:0007218(neuropeptide signaling pathway);GO:0007283(spermatogenesis);GO:0006935(chemotaxis);GO:0006954(inflammatory response);GO:0008283(cell proliferation);GO:0043066(negative regulation of apoptotic process);GO:0001664(G-protein coupled receptor binding);GO:0001525(angiogenesis);GO:0007204(positive regulation of cytosolic calcium ion concentration);GO:0000187(activation of MAPK activity);GO:0019233(sensory perception of pain);GO:0008284(positive regulation of cell proliferation);GO:0045987(positive regulation of smooth muscle contraction);GO:0007623(circadian rhythm);GO:0045765(regulation of angiogenesis)","NA","NA","NA","prokineticin 2 [Source:HGNC Symbol;Acc:HGNC:18455]",{"v":3.847723,"d":"3.85"},{"v":23.968731,"d":"23.97"},{"v":0.160530943419574,"d":"0.16"},{"v":-2.63907668155737,"d":"-2.64"},{"v":2.07419352153953E-4,"d":"0.00"},{"v":0.00437817084969359,"d":"0.00"},"down","yes"]
[1129,0,"chr1","-",6590724,6602869,"ENST00000377658",4,4487,"MSTRG.102","KLHL21","GO:0005737(cytoplasm);GO:0016567(protein ubiquitination);GO:0051301(cell division);GO:0005856(cytoskeleton);GO:0007049(cell cycle);GO:0005819(spindle);GO:0005829(cytosol);GO:0043687(post-translational protein modification);GO:0004842(ubiquitin-protein transferase activity);GO:0031463(Cul3-RING ubiquitin ligase complex);GO:0032465(regulation of cytokinesis);GO:0005827(polar microtubule);GO:0035853(chromosome passenger complex localization to spindle midzone)","NA","NA","NA","kelch like family member 21 [Source:HGNC Symbol;Acc:HGNC:29041]",{"v":1.113972,"d":"1.11"},{"v":6.933075,"d":"6.93"},{"v":0.160675025151178,"d":"0.16"},{"v":-2.63778239668133,"d":"-2.64"},{"v":2.08241846399245E-4,"d":"0.00"},{"v":0.00439089037898641,"d":"0.00"},"down","yes"]
[189286,0,"chr9","+",19230435,19372858,"ENST00000602925",32,6831,"ENSG00000137145","DENND4C","GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0017112(Rab guanyl-nucleotide exchange factor activity);GO:0032869(cellular response to insulin stimulus);GO:0072659(protein localization to plasma membrane);GO:0032593(insulin-responsive compartment);GO:0030904(retromer complex);GO:0006810(transport);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0015031(protein transport);GO:0043547(positive regulation of GTPase activity);GO:0030659(cytoplasmic vesicle membrane);GO:0031410(cytoplasmic vesicle);GO:0005085(guanyl-nucleotide exchange factor activity);GO:0061024(membrane organization);GO:0005794(Golgi apparatus);GO:0043231(intracellular membrane-bounded organelle)","NA","NA","NA","DENN domain containing 4C [Source:HGNC Symbol;Acc:HGNC:26079]",{"v":3.528671,"d":"3.53"},{"v":0.61277,"d":"0.61"},{"v":5.75855704424172,"d":"5.76"},{"v":2.52570735230778,"d":"2.53"},{"v":0.000210986616886112,"d":"0.00"},{"v":0.00444407253795556,"d":"0.00"},"up","yes"]
[111378,0,"chr2","+",74554086,74557554,"ENST00000233668",5,2555,"MSTRG.8845","DOK1","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005515(protein binding);GO:0048471(perinuclear region of cytoplasm);GO:0005158(insulin receptor binding);GO:0007165(signal transduction);GO:0007166(cell surface receptor signaling pathway);GO:0007411(axon guidance);GO:0007169(transmembrane receptor protein tyrosine kinase signaling pathway);GO:0045742(positive regulation of epidermal growth factor receptor signaling pathway);GO:0005057(signal transducer activity, downstream of receptor);GO:0007265(Ras protein signal transduction);GO:0035556(intracellular signal transduction)","05162(Measles)","K14752","NA","docking protein 1 [Source:HGNC Symbol;Acc:HGNC:2990]",{"v":0.936588,"d":"0.94"},{"v":5.920719,"d":"5.92"},{"v":0.158188220045572,"d":"0.16"},{"v":-2.66028592563675,"d":"-2.66"},{"v":0.000212701947064932,"d":"0.00"},{"v":0.00447231571988817,"d":"0.00"},"down","yes"]
[2715,0,"chr1","-",23801885,23825459,"ENST00000374490",9,1600,"MSTRG.237","HMGCL","GO:0046872(metal ion binding);GO:0003824(catalytic activity);GO:0016829(lyase activity);GO:0005739(mitochondrion);GO:0042803(protein homodimerization activity);GO:0000287(magnesium ion binding);GO:0005759(mitochondrial matrix);GO:0005777(peroxisome);GO:0005102(receptor binding);GO:0004419(hydroxymethylglutaryl-CoA lyase activity);GO:0046951(ketone body biosynthetic process);GO:0051262(protein tetramerization);GO:0006629(lipid metabolic process);GO:0030145(manganese ion binding);GO:0006552(leucine catabolic process);GO:0000062(fatty-acyl-CoA binding);GO:0031406(carboxylic acid binding);GO:0001889(liver development);GO:0006637(acyl-CoA metabolic process);GO:0007005(mitochondrion organization);GO:0007584(response to nutrient);GO:0042594(response to starvation);GO:0070542(response to fatty acid);GO:0005743(mitochondrial inner membrane)","00650(Butanoate metabolism);00072(Synthesis and degradation of ketone bodies);00280(Valine, leucine and isoleucine degradation);04146(Peroxisome)","K01640","EC:4.1.3.4","3-hydroxymethyl-3-methylglutaryl-CoA lyase [Source:HGNC Symbol;Acc:HGNC:5005]",{"v":0.493932,"d":"0.49"},{"v":3.258326,"d":"3.26"},{"v":0.151590724807769,"d":"0.15"},{"v":-2.72174661105644,"d":"-2.72"},{"v":2.12775437394519E-4,"d":"0.00"},{"v":0.00447231571988817,"d":"0.00"},"down","yes"]
[114414,0,"chr2","+",130356007,130375409,"ENST00000175756",15,3669,"MSTRG.9106","PTPN18","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016787(hydrolase activity);GO:0004725(protein tyrosine phosphatase activity);GO:0016791(phosphatase activity);GO:0006470(protein dephosphorylation);GO:0016311(dephosphorylation);GO:0035335(peptidyl-tyrosine dephosphorylation);GO:0004721(phosphoprotein phosphatase activity);GO:0005515(protein binding);GO:0005829(cytosol);GO:0038128(ERBB2 signaling pathway);GO:1901185(negative regulation of ERBB signaling pathway);GO:0004726(non-membrane spanning protein tyrosine phosphatase activity)","NA","NA","NA","protein tyrosine phosphatase, non-receptor type 18 [Source:HGNC Symbol;Acc:HGNC:9649]",{"v":8.733228,"d":"8.73"},{"v":1.52525,"d":"1.53"},{"v":5.72576823471562,"d":"5.73"},{"v":2.51746927470445,"d":"2.52"},{"v":0.000213670885329678,"d":"0.00"},{"v":0.00448525750911717,"d":"0.00"},"up","yes"]
[14431,"u","chr1","+",192106200,192139432,"MSTRG.1261.2",4,457,"MSTRG.1261",".","NA","NA","NA","NA","NA",{"v":10.500674,"d":"10.50"},{"v":1.722041,"d":"1.72"},{"v":6.09780719506678,"d":"6.10"},{"v":2.60829053488054,"d":"2.61"},{"v":2.13840402077301E-4,"d":"0.00"},{"v":0.00448525750911717,"d":"0.00"},"up","yes"]
[36794,0,"chr11","+",126355684,126414638,"ENST00000444328",11,1812,"MSTRG.2976","ST3GAL4","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016740(transferase activity);GO:0008373(sialyltransferase activity);GO:0016757(transferase activity, transferring glycosyl groups);GO:0006486(protein glycosylation);GO:0097503(sialylation);GO:0005794(Golgi apparatus);GO:0005576(extracellular region);GO:0032580(Golgi cisterna membrane);GO:0070062(extracellular exosome);GO:0000139(Golgi membrane);GO:0050890(cognition);GO:0016266(O-glycan processing);GO:0018146(keratan sulfate biosynthetic process);GO:0009311(oligosaccharide metabolic process);GO:0003836(beta-galactoside (CMP) alpha-2,3-sialyltransferase activity);GO:0018279(protein N-linked glycosylation via asparagine);GO:0047288(monosialoganglioside sialyltransferase activity)","00601(Glycosphingolipid biosynthesis - lacto and neolacto series)","K03494","EC:2.4.99.4","ST3 beta-galactoside alpha-2,3-sialyltransferase 4 [Source:HGNC Symbol;Acc:HGNC:10864]",{"v":0.847947,"d":"0.85"},{"v":5.402991,"d":"5.40"},{"v":0.156940294736749,"d":"0.16"},{"v":-2.67171228016352,"d":"-2.67"},{"v":2.14787246849861E-4,"d":"0.00"},{"v":0.00450039007880171,"d":"0.00"},"down","yes"]
[4322,0,"chr1","-",36466043,36483278,"ENST00000373104",18,2953,"MSTRG.424","CSF3R","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0007155(cell adhesion);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0004896(cytokine receptor activity);GO:0019221(cytokine-mediated signaling pathway);GO:0005887(integral component of plasma membrane);GO:0007165(signal transduction);GO:0004872(receptor activity);GO:0006952(defense response);GO:0051916(granulocyte colony-stimulating factor binding);GO:0030593(neutrophil chemotaxis);GO:0045637(regulation of myeloid cell differentiation);GO:0097186(amelogenesis)","04630(Jak-STAT signaling pathway);04151(PI3K-Akt signaling pathway);04060(Cytokine-cytokine receptor interaction);04640(Hematopoietic cell lineage);05200(Pathways in cancer)","K05061","NA","colony stimulating factor 3 receptor [Source:HGNC Symbol;Acc:HGNC:2439]",{"v":2.389824,"d":"2.39"},{"v":14.802028,"d":"14.80"},{"v":0.161452471242454,"d":"0.16"},{"v":-2.63081857142108,"d":"-2.63"},{"v":0.000215250641580141,"d":"0.00"},{"v":0.00450537191936296,"d":"0.00"},"down","yes"]
[163117,"j","chr6","-",18225631,18264147,"MSTRG.12699.4",11,1275,"MSTRG.12699","DEK","NA","NA","NA","NA","NA",{"v":14.344286,"d":"14.34"},{"v":2.478699,"d":"2.48"},{"v":5.78702214347123,"d":"5.79"},{"v":2.53282116444946,"d":"2.53"},{"v":0.000215520845737083,"d":"0.00"},{"v":0.00450605238425495,"d":"0.00"},"up","yes"]
[94426,0,"chr19","-",1611168,1650745,"ENST00000588136",19,2658,"ENSG00000071564","TCF3","GO:0046983(protein dimerization activity);GO:0005654(nucleoplasm);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0005737(cytoplasm);GO:0005634(nucleus);GO:0016607(nuclear speck);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0042803(protein homodimerization activity);GO:0005515(protein binding);GO:0007399(nervous system development);GO:0030154(cell differentiation);GO:0003713(transcription coactivator activity);GO:0045893(positive regulation of transcription, DNA-templated);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:0001078(transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:1902036(regulation of hematopoietic stem cell differentiation);GO:0046982(protein heterodimerization activity);GO:0043425(bHLH transcription factor binding);GO:0000790(nuclear chromatin);GO:0070491(repressing transcription factor binding);GO:0070888(E-box binding);GO:0090575(RNA polymerase II transcription factor complex);GO:0051091(positive regulation of sequence-specific DNA binding transcription factor activity);GO:0051149(positive regulation of muscle cell differentiation);GO:0008134(transcription factor binding);GO:0005667(transcription factor complex);GO:0045666(positive regulation of neuron differentiation);GO:0035326(enhancer binding);GO:0030183(B cell differentiation);GO:0070644(vitamin D response element binding);GO:0031435(mitogen-activated protein kinase kinase kinase binding);GO:0002326(B cell lineage commitment);GO:0033152(immunoglobulin V(D)J recombination)","04550(Signaling pathways regulating pluripotency of stem cells);05202(Transcriptional misregulation in cancers);05166(HTLV-I infection)","K09063","NA","transcription factor 3 [Source:HGNC Symbol;Acc:HGNC:11633]",{"v":4.649089,"d":"4.65"},{"v":0.802297,"d":"0.80"},{"v":5.79472315115225,"d":"5.79"},{"v":2.53473973664147,"d":"2.53"},{"v":0.000215734479134001,"d":"0.00"},{"v":0.00450605238425495,"d":"0.00"},"up","yes"]
[11437,"j","chr1","-",154582057,154608160,"MSTRG.1019.1",16,6370,"MSTRG.1019","ADAR","NA","NA","NA","NA","NA",{"v":0.238793,"d":"0.24"},{"v":1.523919,"d":"1.52"},{"v":0.156696648575154,"d":"0.16"},{"v":-2.67395377108013,"d":"-2.67"},{"v":0.000217011961658933,"d":"0.00"},{"v":0.0045279987987519,"d":"0.00"},"down","yes"]
[70035,0,"chr16","-",15865720,15888615,"ENST00000255759",5,2275,"ENSG00000133393","FOPNL","GO:0005737(cytoplasm);GO:0005634(nucleus);GO:0031514(motile cilium);GO:0005813(centrosome);GO:0005856(cytoskeleton);GO:0042995(cell projection);GO:0005815(microtubule organizing center);GO:0034453(microtubule anchoring);GO:0060271(cilium assembly);GO:0005929(cilium);GO:0030030(cell projection organization);GO:0005814(centriole);GO:0036064(ciliary basal body);GO:0034451(centriolar satellite)","NA","NA","NA","FGFR1OP N-terminal like [Source:HGNC Symbol;Acc:HGNC:26435]",{"v":0.517669,"d":"0.52"},{"v":3.340157,"d":"3.34"},{"v":0.154983433413459,"d":"0.15"},{"v":-2.68981408461105,"d":"-2.69"},{"v":0.000217624168832738,"d":"0.00"},{"v":0.00453603278001265,"d":"0.00"},"down","yes"]
[36476,0,"chr11","+",124622875,124635398,"ENST00000284290",8,4468,"ENSG00000154144","TBRG1","GO:0005634(nucleus);GO:0007049(cell cycle);GO:0005515(protein binding);GO:0007050(cell cycle arrest);GO:0008285(negative regulation of cell proliferation);GO:0006260(DNA replication);GO:0032066(nucleolus to nucleoplasm transport);GO:0050821(protein stabilization)","NA","NA","NA","transforming growth factor beta regulator 1 [Source:HGNC Symbol;Acc:HGNC:29551]",{"v":0.915423,"d":"0.92"},{"v":0.148885,"d":"0.15"},{"v":6.14852402861269,"d":"6.15"},{"v":2.6202401287995,"d":"2.62"},{"v":0.000218169805041831,"d":"0.00"},{"v":0.00454266388641845,"d":"0.00"},"up","yes"]
[62436,0,"chr15","-",50241947,50266026,"ENST00000267845",12,2705,"ENSG00000140287","HDC","GO:0003824(catalytic activity);GO:0016829(lyase activity);GO:0005515(protein binding);GO:0016831(carboxy-lyase activity);GO:0030170(pyridoxal phosphate binding);GO:0019752(carboxylic acid metabolic process);GO:0006520(cellular amino acid metabolic process);GO:0005829(cytosol);GO:0042423(catecholamine biosynthetic process);GO:0004398(histidine decarboxylase activity);GO:0001694(histamine biosynthetic process);GO:0006547(histidine metabolic process);GO:0006548(histidine catabolic process)","00340(Histidine metabolism)","K01590","EC:4.1.1.22","histidine decarboxylase [Source:HGNC Symbol;Acc:HGNC:4855]",{"v":1.847824,"d":"1.85"},{"v":0.306064,"d":"0.31"},{"v":6.03737780333525,"d":"6.04"},{"v":2.59392208406331,"d":"2.59"},{"v":0.000220281040779022,"d":"0.00"},{"v":0.00458184564820365,"d":"0.00"},"up","yes"]
[34377,0,"chr11","-",95768953,95789615,"ENST00000398187",11,3823,"ENSG00000077458","FAM76B","GO:0005634(nucleus);GO:0016607(nuclear speck);GO:0005515(protein binding);GO:0016020(membrane);GO:0016021(integral component of membrane)","NA","NA","NA","family with sequence similarity 76 member B [Source:HGNC Symbol;Acc:HGNC:28492]",{"v":0.272841,"d":"0.27"},{"v":1.774386,"d":"1.77"},{"v":0.153766429626924,"d":"0.15"},{"v":-2.70118752720012,"d":"-2.70"},{"v":2.21254151584626E-4,"d":"0.00"},{"v":0.0045925493486611,"d":"0.00"},"down","yes"]
[160027,0,"chr5","+",150357639,150400307,"ENST00000377797",27,5095,"ENSG00000070814","TCOF1","GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005829(cytosol);GO:0001650(fibrillar center);GO:0005515(protein binding);GO:0005730(nucleolus);GO:0006417(regulation of translation);GO:0005215(transporter activity);GO:0046982(protein heterodimerization activity);GO:0001501(skeletal system development);GO:0014029(neural crest formation);GO:0014032(neural crest cell development);GO:0001042(RNA polymerase I core binding);GO:0006810(transport)","03008(Ribosome biogenesis in eukaryotes)","K14562","NA","treacle ribosome biogenesis factor 1 [Source:HGNC Symbol;Acc:HGNC:11654]",{"v":3.634346,"d":"3.63"},{"v":0.631435,"d":"0.63"},{"v":5.75569298502617,"d":"5.76"},{"v":2.52498963919545,"d":"2.52"},{"v":0.000221255632682892,"d":"0.00"},{"v":0.0045925493486611,"d":"0.00"},"up","yes"]
[160469,0,"chr5","+",157241591,157255185,"ENST00000519749",6,3375,"MSTRG.12490","ITK","GO:0005622(intracellular);GO:0035556(intracellular signal transduction);GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0004713(protein tyrosine kinase activity);GO:0005515(protein binding);GO:0004715(non-membrane spanning protein tyrosine kinase activity);GO:0002376(immune system process);GO:0002250(adaptive immune response);GO:0038095(Fc-epsilon receptor signaling pathway);GO:0045087(innate immune response);GO:0001816(cytokine production);GO:0005829(cytosol);GO:0050852(T cell receptor signaling pathway);GO:0007165(signal transduction);GO:0042127(regulation of cell proliferation);GO:0042110(T cell activation);GO:0006968(cellular defense response);GO:0038083(peptidyl-tyrosine autophosphorylation);GO:0031234(extrinsic component of cytoplasmic side of plasma membrane);GO:0007169(transmembrane receptor protein tyrosine kinase signaling pathway);GO:0007202(activation of phospholipase C activity);GO:0001865(NK T cell differentiation);GO:0032609(interferon-gamma production);GO:0032633(interleukin-4 production);GO:0005911(cell-cell junction)","04660(T cell receptor signaling pathway);04670(Leukocyte transendothelial migration);04062(Chemokine signaling pathway)","NA","NA","IL2 inducible T-cell kinase [Source:HGNC Symbol;Acc:HGNC:6171]",{"v":0.265816,"d":"0.27"},{"v":1.729214,"d":"1.73"},{"v":0.153720707789782,"d":"0.15"},{"v":-2.70161657063099,"d":"-2.70"},{"v":0.000223414920471642,"d":"0.00"},{"v":0.00463255361576091,"d":"0.00"},"down","yes"]
[191061,0,"chr9","-",72355833,72364626,"ENST00000343431",7,1073,"MSTRG.14807","ZFAND5","GO:0005737(cytoplasm);GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0003674(molecular_function);GO:0008150(biological_process);GO:0005575(cellular_component);GO:0001701(in utero embryonic development);GO:0001944(vasculature development);GO:0003016(respiratory system process);GO:0010761(fibroblast migration);GO:0048008(platelet-derived growth factor receptor signaling pathway);GO:0048705(skeletal system morphogenesis);GO:0048745(smooth muscle tissue development);GO:0060324(face development)","NA","NA","NA","zinc finger AN1-type containing 5 [Source:HGNC Symbol;Acc:HGNC:13008]",{"v":5.611875,"d":"5.61"},{"v":0.941153,"d":"0.94"},{"v":5.96276588397423,"d":"5.96"},{"v":2.57598169335105,"d":"2.58"},{"v":0.000224071336731813,"d":"0.00"},{"v":0.00464134486707556,"d":"0.00"},"up","yes"]
[180632,0,"chr7","-",157539056,158587773,"ENST00000389413",22,4723,"MSTRG.14161","PTPRN2","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016787(hydrolase activity);GO:0006629(lipid metabolic process);GO:0004725(protein tyrosine phosphatase activity);GO:0016791(phosphatase activity);GO:0006470(protein dephosphorylation);GO:0016311(dephosphorylation);GO:0035335(peptidyl-tyrosine dephosphorylation);GO:0004721(phosphoprotein phosphatase activity);GO:0030054(cell junction);GO:0045202(synapse);GO:0031410(cytoplasmic vesicle);GO:0005886(plasma membrane);GO:0005887(integral component of plasma membrane);GO:0043312(neutrophil degranulation);GO:0030672(synaptic vesicle membrane);GO:0007269(neurotransmitter secretion);GO:0043235(receptor complex);GO:0101003(ficolin-1-rich granule membrane);GO:0030658(transport vesicle membrane);GO:0005001(transmembrane receptor protein tyrosine phosphatase activity);GO:0030667(secretory granule membrane);GO:0035773(insulin secretion involved in cellular response to glucose stimulus);GO:0034260(negative regulation of GTPase activity);GO:0005737(cytoplasm);GO:0005788(endoplasmic reticulum lumen);GO:0030141(secretory granule);GO:0043195(terminal bouton)","04940(Type I diabetes mellitus)","K07817","EC:3.1.3.48","protein tyrosine phosphatase, receptor type N2 [Source:HGNC Symbol;Acc:HGNC:9677]",{"v":0.142351,"d":"0.14"},{"v":0.957557,"d":"0.96"},{"v":0.148660601927614,"d":"0.15"},{"v":-2.74990574026626,"d":"-2.75"},{"v":0.000225023890902217,"d":"0.00"},{"v":0.00465624565133209,"d":"0.00"},"down","yes"]
[138732,0,"chr3","+",101779230,101823623,"ENST00000273347",8,3941,"ENSG00000144815","NXPE3","GO:0005576(extracellular region)","NA","NA","NA","neurexophilin and PC-esterase domain family member 3 [Source:HGNC Symbol;Acc:HGNC:28238]",{"v":0.237635,"d":"0.24"},{"v":1.533219,"d":"1.53"},{"v":0.154990904756594,"d":"0.15"},{"v":-2.68974453775918,"d":"-2.69"},{"v":0.000225431490836924,"d":"0.00"},{"v":0.0046598509410266,"d":"0.00"},"down","yes"]
[154385,0,"chr5","-",39371675,39425233,"ENST00000545653",14,4537,"MSTRG.12014","DAB2","GO:0001934(positive regulation of protein phosphorylation);GO:0090090(negative regulation of canonical Wnt signaling pathway);GO:0006810(transport);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0015031(protein transport);GO:0043231(intracellular membrane-bounded organelle);GO:0005730(nucleolus);GO:0001650(fibrillar center);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0006915(apoptotic process);GO:0006898(receptor-mediated endocytosis);GO:0007275(multicellular organism development);GO:0016055(Wnt signaling pathway);GO:0030154(cell differentiation);GO:0031410(cytoplasmic vesicle);GO:0005905(clathrin-coated pit);GO:0005925(focal adhesion);GO:0005829(cytosol);GO:0006897(endocytosis);GO:0070062(extracellular exosome);GO:0061024(membrane organization);GO:0030335(positive regulation of cell migration);GO:0008022(protein C-terminus binding);GO:0043066(negative regulation of apoptotic process);GO:0030665(clathrin-coated vesicle membrane);GO:0045893(positive regulation of transcription, DNA-templated);GO:0030511(positive regulation of transforming growth factor beta receptor signaling pathway);GO:0030136(clathrin-coated vesicle);GO:0045892(negative regulation of transcription, DNA-templated);GO:0008283(cell proliferation);GO:0045807(positive regulation of endocytosis);GO:0010718(positive regulation of epithelial to mesenchymal transition);GO:0010862(positive regulation of pathway-restricted SMAD protein phosphorylation);GO:0032091(negative regulation of protein binding);GO:0032436(positive regulation of proteasomal ubiquitin-dependent protein catabolic process);GO:0005765(lysosomal membrane);GO:0060766(negative regulation of androgen receptor signaling pathway);GO:0046332(SMAD binding);GO:1903077(negative regulation of protein localization to plasma membrane);GO:2000643(positive regulation of early endosome to late endosome transport);GO:0070022(transforming growth factor beta receptor complex);GO:0035615(clathrin adaptor activity);GO:0038024(cargo receptor activity);GO:0035026(leading edge cell differentiation);GO:0060391(positive regulation of SMAD protein import into nucleus);GO:2000096(positive regulation of Wnt signaling pathway, planar cell polarity pathway);GO:2000370(positive regulation of clathrin-dependent endocytosis)","04144(Endocytosis)","K12475","NA","DAB2, clathrin adaptor protein [Source:HGNC Symbol;Acc:HGNC:2662]",{"v":0.548175,"d":"0.55"},{"v":3.418328,"d":"3.42"},{"v":0.160363487646592,"d":"0.16"},{"v":-2.64058239566015,"d":"-2.64"},{"v":2.2722815404771E-4,"d":"0.00"},{"v":0.00469213214066666,"d":"0.00"},"down","yes"]
[92458,0,"chr18","-",50282349,50287115,"ENST00000590901",13,2562,"MSTRG.7525","CXXC1","GO:0005634(nucleus);GO:0016607(nuclear speck);GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0005829(cytosol);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0045893(positive regulation of transcription, DNA-templated);GO:0005654(nucleoplasm);GO:0036498(IRE1-mediated unfolded protein response);GO:0051568(histone H3-K4 methylation);GO:0042800(histone methyltransferase activity (H3-K4 specific));GO:0035097(histone methyltransferase complex);GO:0048188(Set1C/COMPASS complex);GO:0045322(unmethylated CpG binding);GO:0000987(core promoter proximal region sequence-specific DNA binding);GO:0016363(nuclear matrix)","NA","NA","NA","CXXC finger protein 1 [Source:HGNC Symbol;Acc:HGNC:24343]",{"v":2.699029,"d":"2.70"},{"v":0.454349,"d":"0.45"},{"v":5.94043125438815,"d":"5.94"},{"v":2.57056766940701,"d":"2.57"},{"v":0.000227569401106559,"d":"0.00"},{"v":4.69432417489232E-3,"d":"0.00"},"up","yes"]
[132460,0,"chr22","-",50217689,50244992,"ENST00000498611",23,5274,"MSTRG.10601","TUBGCP6","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005856(cytoskeleton);GO:0005874(microtubule);GO:0000226(microtubule cytoskeleton organization);GO:0008017(microtubule binding);GO:0005813(centrosome);GO:0005815(microtubule organizing center);GO:0043015(gamma-tubulin binding);GO:0007020(microtubule nucleation);GO:0000922(spindle pole);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0005200(structural constituent of cytoskeleton);GO:0031122(cytoplasmic microtubule organization);GO:0090307(mitotic spindle assembly);GO:0008274(gamma-tubulin ring complex);GO:0051415(interphase microtubule nucleation by interphase microtubule organizing center);GO:0000923(equatorial microtubule organizing center);GO:0051298(centrosome duplication);GO:0051321(meiotic cell cycle);GO:0051011(microtubule minus-end binding)","NA","NA","NA","tubulin gamma complex associated protein 6 [Source:HGNC Symbol;Acc:HGNC:18127]",{"v":4.244573,"d":"4.24"},{"v":0.744779,"d":"0.74"},{"v":5.69910402951748,"d":"5.70"},{"v":2.5107351273872,"d":"2.51"},{"v":0.000227959228553632,"d":"0.00"},{"v":0.00469751277168104,"d":"0.00"},"up","yes"]
[128238,0,"chr22","+",17084959,17115694,"ENST00000612619",12,8506,"MSTRG.10099","IL17RA","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0019221(cytokine-mediated signaling pathway);GO:0005887(integral component of plasma membrane);GO:0007166(cell surface receptor signaling pathway);GO:0032747(positive regulation of interleukin-23 production);GO:0072537(fibroblast activation);GO:0097398(cellular response to interleukin-17);GO:0030368(interleukin-17 receptor activity);GO:0005102(receptor binding);GO:0050729(positive regulation of inflammatory response);GO:0050832(defense response to fungus);GO:0071345(cellular response to cytokine stimulus);GO:0071621(granulocyte chemotaxis);GO:1900017(positive regulation of cytokine production involved in inflammatory response);GO:2000664(positive regulation of interleukin-5 secretion);GO:2000667(positive regulation of interleukin-13 secretion)","04060(Cytokine-cytokine receptor interaction);04657(IL-17 signaling pathway)","K05164","NA","interleukin 17 receptor A [Source:HGNC Symbol;Acc:HGNC:5985]",{"v":0.697001,"d":"0.70"},{"v":4.283961,"d":"4.28"},{"v":0.162700127288741,"d":"0.16"},{"v":-2.61971271518139,"d":"-2.62"},{"v":0.000231441230480363,"d":"0.00"},{"v":0.00476434895900195,"d":"0.00"},"down","yes"]
[146118,"j","chr4","-",15604072,15681679,"MSTRG.11545.1",13,4350,"MSTRG.11545","FBXL5","NA","NA","NA","NA","NA",{"v":2.731877,"d":"2.73"},{"v":0.473422,"d":"0.47"},{"v":5.77049017578397,"d":"5.77"},{"v":2.52869387418034,"d":"2.53"},{"v":2.32998815761459E-4,"d":"0.00"},{"v":0.00479147307221918,"d":"0.00"},"up","yes"]
[96789,0,"chr19","+",11435635,11450968,"ENST00000592741",18,2100,"MSTRG.7840","PRKCSH","GO:0046872(metal ion binding);GO:0005783(endoplasmic reticulum);GO:0005509(calcium ion binding);GO:0044267(cellular protein metabolic process);GO:0005622(intracellular);GO:0043687(post-translational protein modification);GO:0044325(ion channel binding);GO:0006457(protein folding);GO:0006491(N-glycan processing);GO:0005788(endoplasmic reticulum lumen);GO:0035556(intracellular signal transduction);GO:0051219(phosphoprotein binding);GO:0005080(protein kinase C binding);GO:0003723(RNA binding);GO:0001701(in utero embryonic development);GO:0001889(liver development);GO:0006807(nitrogen compound metabolic process);GO:0010977(negative regulation of neuron projection development);GO:0051291(protein heterooligomerization);GO:0072001(renal system development)","04141(Protein processing in endoplasmic reticulum)","K08288","NA","protein kinase C substrate 80K-H [Source:HGNC Symbol;Acc:HGNC:9411]",{"v":0.652174,"d":"0.65"},{"v":4.132881,"d":"4.13"},{"v":0.15780130131983,"d":"0.16"},{"v":-2.66381899219807,"d":"-2.66"},{"v":2.34466093272562E-4,"d":"0.00"},{"v":0.00481668616303139,"d":"0.00"},"down","yes"]
[187991,0,"chr8","-",143579729,143597400,"ENST00000531621",7,840,"MSTRG.14619","EEF1D","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0006412(translation);GO:0005829(cytosol);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0001650(fibrillar center);GO:0005783(endoplasmic reticulum);GO:0005515(protein binding);GO:0004871(signal transducer activity);GO:0003746(translation elongation factor activity);GO:0006414(translational elongation);GO:0005853(eukaryotic translation elongation factor 1 complex);GO:0007165(signal transduction);GO:0045296(cadherin binding);GO:0043123(positive regulation of I-kappaB kinase/NF-kappaB signaling);GO:0008135(translation factor activity, RNA binding);GO:0071479(cellular response to ionizing radiation)","05168(Herpes simplex infection)","NA","NA","eukaryotic translation elongation factor 1 delta [Source:HGNC Symbol;Acc:HGNC:3211]",{"v":7.952579,"d":"7.95"},{"v":1.356194,"d":"1.36"},{"v":5.86389484100357,"d":"5.86"},{"v":2.55185923141801,"d":"2.55"},{"v":0.000234899657322678,"d":"0.00"},{"v":4.82063346086251E-3,"d":"0.00"},"up","yes"]
[52670,0,"chr14","-",21399606,21409890,"ENST00000555935",16,2617,"MSTRG.4144","CHD8","GO:0005634(nucleus);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0005654(nucleoplasm);GO:0016787(hydrolase activity);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0016569(covalent chromatin modification);GO:0004386(helicase activity);GO:0032508(DNA duplex unwinding);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0043044(ATP-dependent chromatin remodeling);GO:0016055(Wnt signaling pathway);GO:0045893(positive regulation of transcription, DNA-templated);GO:0016817(hydrolase activity, acting on acid anhydrides);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0030178(negative regulation of Wnt signaling pathway);GO:0043234(protein complex);GO:0042393(histone binding);GO:0045892(negative regulation of transcription, DNA-templated);GO:0071339(MLL1 complex);GO:0008013(beta-catenin binding);GO:0007420(brain development);GO:0035064(methylated histone binding);GO:0002039(p53 binding);GO:0060070(canonical Wnt signaling pathway);GO:0008094(DNA-dependent ATPase activity);GO:0090090(negative regulation of canonical Wnt signaling pathway);GO:0003682(chromatin binding);GO:0003678(DNA helicase activity);GO:0045945(positive regulation of transcription from RNA polymerase III promoter);GO:0048565(digestive tract development);GO:0070016(armadillo repeat domain binding);GO:0001701(in utero embryonic development);GO:0043066(negative regulation of apoptotic process);GO:2000270(negative regulation of fibroblast apoptotic process)","04310(Wnt signaling pathway)","NA","NA","chromodomain helicase DNA binding protein 8 [Source:HGNC Symbol;Acc:HGNC:20153]",{"v":2.39062,"d":"2.39"},{"v":0.401262,"d":"0.40"},{"v":5.95775328837518,"d":"5.96"},{"v":2.57476838256577,"d":"2.57"},{"v":0.000238305253954608,"d":"0.00"},{"v":0.00488550237265463,"d":"0.00"},"up","yes"]
[14456,0,"chr1","+",192809039,192810899,"ENST00000483295",2,877,"MSTRG.1266","RGS2","GO:0010614(negative regulation of cardiac muscle hypertrophy);GO:0060452(positive regulation of cardiac muscle contraction);GO:0071877(regulation of adrenergic receptor signaling pathway);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005829(cytosol);GO:0005739(mitochondrion);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0005096(GTPase activator activity);GO:0007049(cell cycle);GO:0048487(beta-tubulin binding);GO:0007283(spermatogenesis);GO:0010519(negative regulation of phospholipase activity);GO:0031116(positive regulation of microtubule polymerization);GO:0043407(negative regulation of MAP kinase activity);GO:0043547(positive regulation of GTPase activity);GO:0043951(negative regulation of cAMP-mediated signaling);GO:0045744(negative regulation of G-protein coupled receptor protein signaling pathway);GO:0050873(brown fat cell differentiation);GO:0055119(relaxation of cardiac muscle);GO:0060087(relaxation of vascular smooth muscle);GO:0009898(cytoplasmic side of plasma membrane);GO:0043005(neuron projection);GO:0005730(nucleolus);GO:0006417(regulation of translation);GO:0009968(negative regulation of signal transduction);GO:0008277(regulation of G-protein coupled receptor protein signaling pathway);GO:0005516(calmodulin binding);GO:0001965(G-protein alpha-subunit binding)","04022(cGMP - PKG signaling pathway);04921(Oxytocin signaling pathway);04740(Olfactory transduction)","NA","NA","regulator of G protein signaling 2 [Source:HGNC Symbol;Acc:HGNC:9998]",{"v":6.491094,"d":"6.49"},{"v":39.636387,"d":"39.64"},{"v":0.163766036495708,"d":"0.16"},{"v":-2.61029190799282,"d":"-2.61"},{"v":0.000239705048231963,"d":"0.00"},{"v":0.00490130137649063,"d":"0.00"},"down","yes"]
[118882,0,"chr2","+",216415113,216483017,"ENST00000392128",15,2431,"MSTRG.9406","SMARCAL1","GO:0005634(nucleus);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0005654(nucleoplasm);GO:0016787(hydrolase activity);GO:0004386(helicase activity);GO:0005515(protein binding);GO:0006974(cellular response to DNA damage stimulus);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0031297(replication fork processing);GO:0008094(DNA-dependent ATPase activity);GO:0035861(site of double-strand break);GO:0090656(t-circle formation);GO:0005662(DNA replication factor A complex);GO:0006259(DNA metabolic process);GO:0000733(DNA strand renaturation);GO:0036310(annealing helicase activity)","NA","NA","NA","SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a like 1 [Source:HGNC Symbol;Acc:HGNC:11102]",{"v":0.270939,"d":"0.27"},{"v":1.814741,"d":"1.81"},{"v":0.149298990875282,"d":"0.15"},{"v":-2.7437236806818,"d":"-2.74"},{"v":2.39771734282636E-4,"d":"0.00"},{"v":0.00490130137649063,"d":"0.00"},"down","yes"]
[92359,0,"chr18","-",49488453,49492482,"ENST00000618619",8,747,"MSTRG.7521","RPL17","GO:0003723(RNA binding);GO:0005634(nucleus);GO:0006412(translation);GO:0030529(intracellular ribonucleoprotein complex);GO:0005622(intracellular);GO:0003735(structural constituent of ribosome);GO:0005840(ribosome);GO:0015934(large ribosomal subunit);GO:0005829(cytosol);GO:0005515(protein binding);GO:0006413(translational initiation);GO:0006364(rRNA processing);GO:0000184(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay);GO:0019083(viral transcription);GO:0006614(SRP-dependent cotranslational protein targeting to membrane);GO:0022625(cytosolic large ribosomal subunit)","03010(Ribosome)","K02880","NA","ribosomal protein L17 [Source:HGNC Symbol;Acc:HGNC:10307]",{"v":7.15659,"d":"7.16"},{"v":1.204336,"d":"1.20"},{"v":5.94235329675439,"d":"5.94"},{"v":2.57103438173398,"d":"2.57"},{"v":2.3981227187657E-4,"d":"0.00"},{"v":0.00490130137649063,"d":"0.00"},"up","yes"]
[78071,0,"chr17","+",4715589,4721138,"ENST00000571206",13,1659,"MSTRG.6331","ARRB2","GO:0005737(cytoplasm);GO:0051898(negative regulation of protein kinase B signaling);GO:0007179(transforming growth factor beta receptor signaling pathway);GO:0006810(transport);GO:0005634(nucleus);GO:0016020(membrane);GO:0015031(protein transport);GO:0043231(intracellular membrane-bounded organelle);GO:0016567(protein ubiquitination);GO:0007165(signal transduction);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0031410(cytoplasmic vesicle);GO:0005905(clathrin-coated pit);GO:0005829(cytosol);GO:0006366(transcription from RNA polymerase II promoter);GO:0061024(membrane organization);GO:0016579(protein deubiquitination);GO:0060071(Wnt signaling pathway, planar cell polarity pathway);GO:0032947(protein complex scaffold);GO:0032088(negative regulation of NF-kappaB transcription factor activity);GO:0031625(ubiquitin protein ligase binding);GO:0005102(receptor binding);GO:0019899(enzyme binding);GO:0045953(negative regulation of natural killer cell mediated cytotoxicity);GO:0070374(positive regulation of ERK1 and ERK2 cascade);GO:0001664(G-protein coupled receptor binding);GO:0030168(platelet activation);GO:0043161(proteasome-mediated ubiquitin-dependent protein catabolic process);GO:0060326(cell chemotaxis);GO:0009968(negative regulation of signal transduction);GO:0031397(negative regulation of protein ubiquitination);GO:0031398(positive regulation of protein ubiquitination);GO:0030139(endocytic vesicle);GO:0002031(G-protein coupled receptor internalization);GO:0002092(positive regulation of receptor internalization);GO:0099565(chemical synaptic transmission, postsynaptic);GO:0031701(angiotensin receptor binding);GO:0002032(desensitization of G-protein coupled receptor protein signaling pathway by arrestin);GO:0007212(dopamine receptor signaling pathway);GO:0031623(receptor internalization);GO:0060765(regulation of androgen receptor signaling pathway);GO:0019904(protein domain specific binding);GO:0031691(alpha-1A adrenergic receptor binding);GO:0031692(alpha-1B adrenergic receptor binding);GO:0031702(type 1 angiotensin receptor binding);GO:0031748(D1 dopamine receptor binding);GO:0031762(follicle-stimulating hormone receptor binding);GO:0031826(type 2A serotonin receptor binding);GO:0031859(platelet activating factor receptor binding);GO:0032403(protein complex binding);GO:0043422(protein kinase B binding);GO:0051019(mitogen-activated protein kinase binding);GO:0071889(14-3-3 protein binding);GO:0001932(regulation of protein phosphorylation);GO:0001933(negative regulation of protein phosphorylation);GO:0001934(positive regulation of protein phosphorylation);GO:0006897(endocytosis);GO:0007186(G-protein coupled receptor signaling pathway);GO:0007420(brain development);GO:0007628(adult walking behavior);GO:0008277(regulation of G-protein coupled receptor protein signaling pathway);GO:0010628(positive regulation of gene expression);GO:0032226(positive regulation of synaptic transmission, dopaminergic);GO:0032691(negative regulation of interleukin-1 beta production);GO:0032695(negative regulation of interleukin-12 production);GO:0032715(negative regulation of interleukin-6 production);GO:0032720(negative regulation of tumor necrosis factor production);GO:0033138(positive regulation of peptidyl-serine phosphorylation);GO:0034122(negative regulation of toll-like receptor signaling pathway);GO:0034260(negative regulation of GTPase activity);GO:0034392(negative regulation of smooth muscle cell apoptotic process);GO:0042699(follicle-stimulating hormone signaling pathway);GO:0043154(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process);GO:0050731(positive regulation of peptidyl-tyrosine phosphorylation);GO:0050965(detection of temperature stimulus involved in sensory perception of pain);GO:0051897(positive regulation of protein kinase B signaling);GO:0051928(positive regulation of calcium ion transport);GO:0090201(negative regulation of release of cytochrome c from mitochondria);GO:2000573(positive regulation of DNA biosynthetic process);GO:2000727(positive regulation of cardiac muscle cell differentiation);GO:0005622(intracellular);GO:0014069(postsynaptic density);GO:0016323(basolateral plasma membrane);GO:0043197(dendritic spine);GO:0045211(postsynaptic membrane)","04010(MAPK signaling pathway);04340(Hedgehog signaling pathway);04144(Endocytosis);04062(Chemokine signaling pathway);04926(Relaxin signaling pathway);04728(Dopaminergic synapse);04740(Olfactory transduction);05032(Morphine addiction)","NA","NA","arrestin beta 2 [Source:HGNC Symbol;Acc:HGNC:712]",{"v":33.669113,"d":"33.67"},{"v":5.999175,"d":"6.00"},{"v":5.61229052328028,"d":"5.61"},{"v":2.48858969278659,"d":"2.49"},{"v":0.000240185070615124,"d":"0.00"},{"v":0.00490390131906216,"d":"0.00"},"up","yes"]
[126682,0,"chr21","+",33403432,33437521,"ENST00000381995",8,1742,"MSTRG.10004","IFNGR2","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005794(Golgi apparatus);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005886(plasma membrane);GO:0000139(Golgi membrane);GO:0030659(cytoplasmic vesicle membrane);GO:0031410(cytoplasmic vesicle);GO:0005887(integral component of plasma membrane);GO:0004920(interleukin-10 receptor activity);GO:0007166(cell surface receptor signaling pathway);GO:0009615(response to virus);GO:0060333(interferon-gamma-mediated signaling pathway);GO:0060334(regulation of interferon-gamma-mediated signaling pathway);GO:0004906(interferon-gamma receptor activity);GO:0051607(defense response to virus)","04630(Jak-STAT signaling pathway);04066(HIF-1 signaling pathway);04060(Cytokine-cytokine receptor interaction);04217(Necroptosis);04650(Natural killer cell mediated cytotoxicity);04658(Th1 and Th2 cell differentiation);04659(Th17 cell differentiation);04380(Osteoclast differentiation);05200(Pathways in cancer);05321(Inflammatiory bowel disease (IBD));05132(Salmonella infection);05152(Tuberculosis);05162(Measles);05164(Influenza A);05168(Herpes simplex infection);05145(Toxoplasmosis);05140(Leishmaniasis);05142(Chagas disease (American trypanosomiasis))","K05133","NA","interferon gamma receptor 2 [Source:HGNC Symbol;Acc:HGNC:5440]",{"v":1.373909,"d":"1.37"},{"v":8.544207,"d":"8.54"},{"v":0.160800060204534,"d":"0.16"},{"v":-2.6366601482165,"d":"-2.64"},{"v":0.000241511801908785,"d":"0.00"},{"v":0.00492595266651136,"d":"0.00"},"down","yes"]
[9972,0,"chr1","-",144887265,145095528,"ENST00000612199",10,7120,"ENSG00000196369","SRGAP2B","GO:0043547(positive regulation of GTPase activity);GO:0007399(nervous system development);GO:0005737(cytoplasm);GO:0005096(GTPase activator activity);GO:0048365(Rac GTPase binding);GO:0030336(negative regulation of cell migration)","NA","NA","NA","SLIT-ROBO Rho GTPase activating protein 2B [Source:HGNC Symbol;Acc:HGNC:35237]",{"v":0.103989,"d":"0.10"},{"v":0.678208,"d":"0.68"},{"v":0.153329067188827,"d":"0.15"},{"v":-2.70529687464199,"d":"-2.71"},{"v":0.000243734263522353,"d":"0.00"},{"v":0.00496144051670791,"d":"0.00"},"down","yes"]
[110278,0,"chr2","+",64228468,64252859,"ENST00000451350",4,1504,"MSTRG.8752","AC012368.1","NA","NA","NA","NA","NA",{"v":1.730953,"d":"1.73"},{"v":10.680642,"d":"10.68"},{"v":0.162064508856303,"d":"0.16"},{"v":-2.62535991089903,"d":"-2.63"},{"v":0.000243748655192831,"d":"0.00"},{"v":0.00496144051670791,"d":"0.00"},"down","yes"]
[16330,0,"chr1","+",223758226,223776018,"ENST00000487223",10,2991,"MSTRG.1408","CAPN2","GO:0016787(hydrolase activity);GO:0005622(intracellular);GO:0008233(peptidase activity);GO:0008234(cysteine-type peptidase activity);GO:0006508(proteolysis);GO:0004198(calcium-dependent cysteine-type endopeptidase activity);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0046872(metal ion binding);GO:0005829(cytosol);GO:0005509(calcium ion binding);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0005925(focal adhesion);GO:0030425(dendrite);GO:0051493(regulation of cytoskeleton organization);GO:0071230(cellular response to amino acid stimulus);GO:0070062(extracellular exosome);GO:0005783(endoplasmic reticulum);GO:0022617(extracellular matrix disassembly);GO:0045121(membrane raft);GO:0005794(Golgi apparatus);GO:0008092(cytoskeletal protein binding);GO:0051603(proteolysis involved in cellular protein catabolic process);GO:0046982(protein heterodimerization activity);GO:0001666(response to hypoxia);GO:0001824(blastocyst development);GO:0007520(myoblast fusion);GO:0016540(protein autoprocessing);GO:0000785(chromatin);GO:0005634(nucleus);GO:0005764(lysosome);GO:0030864(cortical actin cytoskeleton);GO:0031143(pseudopodium);GO:0097038(perinuclear endoplasmic reticulum)","04141(Protein processing in endoplasmic reticulum);04210(Apoptosis);04217(Necroptosis);04218(Cellular senescence);04510(Focal adhesion);05010(Alzheimer's disease)","NA","NA","calpain 2 [Source:HGNC Symbol;Acc:HGNC:1479]",{"v":1.874666,"d":"1.87"},{"v":0.317984,"d":"0.32"},{"v":5.89547272818758,"d":"5.90"},{"v":2.5596075002734,"d":"2.56"},{"v":0.000244457479933941,"d":"0.00"},{"v":0.00497080138423721,"d":"0.00"},"up","yes"]
[35723,0,"chr11","+",118406127,118409610,"ENST00000527186",2,1582,"MSTRG.2895","ATP5L","GO:0006810(transport);GO:0016020(membrane);GO:0005739(mitochondrion);GO:0005743(mitochondrial inner membrane);GO:0006811(ion transport);GO:0099132(ATP hydrolysis coupled cation transmembrane transport);GO:0015078(hydrogen ion transmembrane transporter activity);GO:0015992(proton transport);GO:0015986(ATP synthesis coupled proton transport);GO:0070062(extracellular exosome);GO:0016887(ATPase activity);GO:0000276(mitochondrial proton-transporting ATP synthase complex, coupling factor F(o));GO:0006754(ATP biosynthetic process);GO:0046933(proton-transporting ATP synthase activity, rotational mechanism);GO:0022857(transmembrane transporter activity);GO:0042407(cristae formation);GO:0042776(mitochondrial ATP synthesis coupled proton transport);GO:0005753(mitochondrial proton-transporting ATP synthase complex);GO:0045263(proton-transporting ATP synthase complex, coupling factor F(o))","00190(Oxidative phosphorylation)","NA","NA","ATP synthase, H+ transporting, mitochondrial Fo complex subunit G [Source:HGNC Symbol;Acc:HGNC:14247]",{"v":3.062732,"d":"3.06"},{"v":0.51194,"d":"0.51"},{"v":5.98259952338165,"d":"5.98"},{"v":2.58077249187992,"d":"2.58"},{"v":0.000245477072642906,"d":"0.00"},{"v":0.00498645593747055,"d":"0.00"},"up","yes"]
[11316,"j","chr1","-",154156355,154183214,"MSTRG.1004.3",6,1924,"MSTRG.1004","TPM3","NA","NA","NA","NA","NA",{"v":20.038612,"d":"20.04"},{"v":120.839973,"d":"120.84"},{"v":0.165827676906217,"d":"0.17"},{"v":-2.59224327983279,"d":"-2.59"},{"v":0.000246189380721064,"d":"0.00"},{"v":0.00499113295704327,"d":"0.00"},"down","yes"]
[148030,0,"chr4","-",70657269,70681817,"ENST00000470866",4,275,"MSTRG.11653","JCHAIN","GO:0042803(protein homodimerization activity);GO:0005576(extracellular region);GO:0006955(immune response);GO:0005615(extracellular space);GO:0045087(innate immune response);GO:0003823(antigen binding);GO:0002250(adaptive immune response);GO:0006898(receptor-mediated endocytosis);GO:0050900(leukocyte migration);GO:0031210(phosphatidylcholine binding);GO:0070062(extracellular exosome);GO:0001895(retina homeostasis);GO:0072562(blood microparticle);GO:0019731(antibacterial humoral response);GO:0032461(positive regulation of protein oligomerization);GO:0003697(single-stranded DNA binding);GO:0042834(peptidoglycan binding);GO:0034987(immunoglobulin receptor binding);GO:0019862(IgA binding);GO:0030674(protein binding, bridging);GO:0003094(glomerular filtration);GO:0060267(positive regulation of respiratory burst);GO:0071748(monomeric IgA immunoglobulin complex);GO:0071750(dimeric IgA immunoglobulin complex);GO:0071751(secretory IgA immunoglobulin complex);GO:0071752(secretory dimeric IgA immunoglobulin complex);GO:0071756(pentameric IgM immunoglobulin complex)","NA","NA","NA","joining chain of multimeric IgA and IgM [Source:HGNC Symbol;Acc:HGNC:5713]",{"v":18.635235,"d":"18.64"},{"v":3.138568,"d":"3.14"},{"v":5.93749601729196,"d":"5.94"},{"v":2.56985464061136,"d":"2.57"},{"v":0.000246207229701904,"d":"0.00"},{"v":0.00499113295704327,"d":"0.00"},"up","yes"]
[182231,0,"chr8","+",23528805,23575463,"ENST00000519973",4,4823,"MSTRG.14243","SLC25A37","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005743(mitochondrial inner membrane);GO:0005739(mitochondrion);GO:0006811(ion transport);GO:0006839(mitochondrial transport);GO:0055072(iron ion homeostasis);GO:0034755(iron ion transmembrane transport);GO:0005381(iron ion transmembrane transporter activity);GO:0048250(mitochondrial iron ion transport)","NA","NA","NA","solute carrier family 25 member 37 [Source:HGNC Symbol;Acc:HGNC:29786]",{"v":2.477211,"d":"2.48"},{"v":14.971626,"d":"14.97"},{"v":0.165460384864009,"d":"0.17"},{"v":-2.59544225188225,"d":"-2.60"},{"v":0.000246752746973027,"d":"0.00"},{"v":0.0049971185107073,"d":"0.00"},"down","yes"]
[31118,0,"chr11","-",65180021,65181834,"ENST00000526623",2,1662,"MSTRG.2532","AP003068.2","NA","NA","NA","NA","NA",{"v":2.013306,"d":"2.01"},{"v":12.355291,"d":"12.36"},{"v":0.16295091714149,"d":"0.16"},{"v":-2.61749062282466,"d":"-2.62"},{"v":0.00024706886556266,"d":"0.00"},{"v":0.00499845097016738,"d":"0.00"},"down","yes"]
[198163,"j","chrX","+",71533025,71575836,"MSTRG.15358.1",20,8533,"MSTRG.15358","OGT","NA","NA","NA","NA","NA",{"v":6.251899,"d":"6.25"},{"v":1.117556,"d":"1.12"},{"v":5.59426015340618,"d":"5.59"},{"v":2.483947345931,"d":"2.48"},{"v":0.000247908496239765,"d":"0.00"},{"v":0.00501036118716157,"d":"0.01"},"up","yes"]
[4878,0,"chr1","+",42456561,42460414,"ENST00000372556",3,984,"ENSG00000127125","PPCS","GO:0016874(ligase activity);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0009108(coenzyme biosynthetic process);GO:0015937(coenzyme A biosynthetic process);GO:0004632(phosphopantothenate--cysteine ligase activity)","00770(Pantothenate and CoA biosynthesis)","NA","NA","phosphopantothenoylcysteine synthetase [Source:HGNC Symbol;Acc:HGNC:25686]",{"v":0.964785,"d":"0.96"},{"v":6.122447,"d":"6.12"},{"v":0.157581600951384,"d":"0.16"},{"v":-2.66582899769314,"d":"-2.67"},{"v":2.49559960999087E-4,"d":"0.00"},{"v":0.00503863832278034,"d":"0.01"},"down","yes"]
[133050,0,"chr3","+",9649433,9702393,"ENST00000353332",18,2368,"MSTRG.10630","MTMR14","GO:0005737(cytoplasm);GO:0016787(hydrolase activity);GO:0004725(protein tyrosine phosphatase activity);GO:0016311(dephosphorylation);GO:0035335(peptidyl-tyrosine dephosphorylation);GO:0005515(protein binding);GO:0048471(perinuclear region of cytoplasm);GO:0006470(protein dephosphorylation);GO:0005829(cytosol);GO:0001726(ruffle);GO:0006661(phosphatidylinositol biosynthetic process);GO:0004722(protein serine/threonine phosphatase activity);GO:0004438(phosphatidylinositol-3-phosphatase activity);GO:0052629(phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity);GO:0016236(macroautophagy)","00562(Inositol phosphate metabolism);04070(Phosphatidylinositol signaling system);04140(Autophagy - animal)","K18086","EC:3.1.3.64;EC:3.1.3.95","myotubularin related protein 14 [Source:HGNC Symbol;Acc:HGNC:26190]",{"v":1.113108,"d":"1.11"},{"v":6.852252,"d":"6.85"},{"v":0.162444113263785,"d":"0.16"},{"v":-2.62198463142326,"d":"-2.62"},{"v":2.51164110441629E-4,"d":"0.00"},{"v":0.00506590399727116,"d":"0.01"},"down","yes"]
[123416,0,"chr20","-",35953617,35954626,"ENST00000305978",2,902,"MSTRG.9701","SCAND1","GO:0005634(nucleus);GO:0006355(regulation of transcription, DNA-templated);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0005515(protein binding);GO:0042802(identical protein binding);GO:0003713(transcription coactivator activity)","NA","NA","NA","SCAN domain containing 1 [Source:HGNC Symbol;Acc:HGNC:10566]",{"v":8.561687,"d":"8.56"},{"v":1.47545,"d":"1.48"},{"v":5.80276322477888,"d":"5.80"},{"v":2.53674006254517,"d":"2.54"},{"v":0.00025182443913263,"d":"0.00"},{"v":0.00507409727608512,"d":"0.01"},"up","yes"]
[20792,0,"chr10","+",68332122,68342272,"ENST00000354695",10,1332,"MSTRG.1741","HNRNPH3","GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0006397(mRNA processing);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0030529(intracellular ribonucleoprotein complex);GO:0005515(protein binding);GO:0005681(spliceosomal complex);GO:0000398(mRNA splicing, via spliceosome);GO:0030855(epithelial cell differentiation);GO:0008380(RNA splicing);GO:0006396(RNA processing);GO:0019013(viral nucleocapsid)","NA","NA","NA","heterogeneous nuclear ribonucleoprotein H3 [Source:HGNC Symbol;Acc:HGNC:5043]",{"v":15.298136,"d":"15.30"},{"v":2.718933,"d":"2.72"},{"v":5.62652187457359,"d":"5.63"},{"v":2.49224337258529,"d":"2.49"},{"v":0.000252220961031773,"d":"0.00"},{"v":0.005076934657392,"d":"0.01"},"up","yes"]
[173794,0,"chr7","+",45027634,45076469,"ENST00000381112",10,1881,"MSTRG.13636","CCM2","GO:0005737(cytoplasm);GO:0005739(mitochondrion);GO:0005515(protein binding);GO:0007275(multicellular organism development);GO:0007229(integrin-mediated signaling pathway);GO:0051403(stress-activated MAPK cascade);GO:0001570(vasculogenesis);GO:0061154(endothelial tube morphogenesis);GO:0001568(blood vessel development);GO:0001701(in utero embryonic development);GO:0001885(endothelial cell development);GO:0001944(vasculature development);GO:0007507(heart development);GO:0035264(multicellular organism growth);GO:0045216(cell-cell junction organization);GO:0048839(inner ear development);GO:0048845(venous blood vessel morphogenesis);GO:0060039(pericardium development);GO:0060837(blood vessel endothelial cell differentiation);GO:0043234(protein complex)","NA","NA","NA","CCM2 scaffolding protein [Source:HGNC Symbol;Acc:HGNC:21708]",{"v":6.573639,"d":"6.57"},{"v":1.153935,"d":"1.15"},{"v":5.69671515293322,"d":"5.70"},{"v":2.51013027039593,"d":"2.51"},{"v":0.000252473763761531,"d":"0.00"},{"v":0.005076934657392,"d":"0.01"},"up","yes"]
[155010,0,"chr5","+",57173948,57264679,"ENST00000424459",13,4683,"MSTRG.12067","GPBP1","GO:0005634(nucleus);GO:0043231(intracellular membrane-bounded organelle);GO:0005829(cytosol);GO:0045893(positive regulation of transcription, DNA-templated);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0005886(plasma membrane);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0005737(cytoplasm);GO:0006355(regulation of transcription, DNA-templated);GO:0005515(protein binding)","NA","NA","NA","GC-rich promoter binding protein 1 [Source:HGNC Symbol;Acc:HGNC:29520]",{"v":0.695465,"d":"0.70"},{"v":4.249617,"d":"4.25"},{"v":0.163653571604218,"d":"0.16"},{"v":-2.61128300653179,"d":"-2.61"},{"v":0.000253575703143823,"d":"0.00"},{"v":0.00509396342090127,"d":"0.01"},"down","yes"]
[49679,0,"chr13","-",36301640,36346797,"ENST00000451493",9,4944,"ENSG00000133104","SPART","GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0051301(cell division);GO:0005886(plasma membrane);GO:0030496(midbody);GO:0005515(protein binding);GO:0031625(ubiquitin protein ligase binding);GO:0051881(regulation of mitochondrial membrane potential);GO:0005741(mitochondrial outer membrane);GO:0009838(abscission);GO:0030514(negative regulation of BMP signaling pathway);GO:0034389(lipid particle organization);GO:0048698(negative regulation of collateral sprouting in absence of injury);GO:0050905(neuromuscular process);GO:0060612(adipose tissue development);GO:0005811(lipid particle);GO:0045202(synapse)","04144(Endocytosis)","K19366","NA","spartin [Source:HGNC Symbol;Acc:HGNC:18514]",{"v":0.196853,"d":"0.20"},{"v":1.258308,"d":"1.26"},{"v":0.156442619771948,"d":"0.16"},{"v":-2.67629449427948,"d":"-2.68"},{"v":0.00025441823257576,"d":"0.00"},{"v":0.00510575202821385,"d":"0.01"},"down","yes"]
[181930,0,"chr8","+",22059223,22082524,"ENST00000519907",15,2658,"MSTRG.14210","DMTN","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0003779(actin binding);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0051693(actin filament capping);GO:0005856(cytoskeleton);GO:0042995(cell projection);GO:0005515(protein binding);GO:0048471(perinuclear region of cytoplasm);GO:0031410(cytoplasmic vesicle);GO:0007010(cytoskeleton organization);GO:0032956(regulation of actin cytoskeleton organization);GO:0055085(transmembrane transport);GO:0012505(endomembrane system);GO:0005102(receptor binding);GO:0008360(regulation of cell shape);GO:0051017(actin filament bundle assembly);GO:0030036(actin cytoskeleton organization);GO:0005884(actin filament);GO:0051895(negative regulation of focal adhesion assembly);GO:0090315(negative regulation of protein targeting to membrane);GO:1900025(negative regulation of substrate adhesion-dependent cell spreading);GO:0006461(protein complex assembly);GO:0015629(actin cytoskeleton);GO:0071320(cellular response to cAMP);GO:0071277(cellular response to calcium ion);GO:0035584(calcium-mediated signaling using intracellular calcium source);GO:0051489(regulation of filopodium assembly);GO:1900026(positive regulation of substrate adhesion-dependent cell spreading);GO:0090303(positive regulation of wound healing);GO:0090527(actin filament reorganization);GO:2001046(positive regulation of integrin-mediated signaling pathway);GO:0033137(negative regulation of peptidyl-serine phosphorylation);GO:0030507(spectrin binding);GO:0010591(regulation of lamellipodium assembly);GO:0048821(erythrocyte development);GO:0010763(positive regulation of fibroblast migration);GO:0010801(negative regulation of peptidyl-threonine phosphorylation);GO:0010812(negative regulation of cell-substrate adhesion);GO:0030194(positive regulation of blood coagulation);GO:0035585(calcium-mediated signaling using extracellular calcium source);GO:0050732(negative regulation of peptidyl-tyrosine phosphorylation);GO:0070560(protein secretion by platelet);GO:1901731(positive regulation of platelet aggregation);GO:0014731(spectrin-associated cytoskeleton);GO:0031095(platelet dense tubular network membrane);GO:0031253(cell projection membrane);GO:0043621(protein self-association);GO:0014069(postsynaptic density);GO:0030863(cortical cytoskeleton)","NA","NA","NA","dematin actin binding protein [Source:HGNC Symbol;Acc:HGNC:3382]",{"v":15.592544,"d":"15.59"},{"v":2.79719,"d":"2.80"},{"v":5.57435998269692,"d":"5.57"},{"v":2.47880617224475,"d":"2.48"},{"v":0.000255524765789814,"d":"0.00"},{"v":5.12280976234036E-3,"d":"0.01"},"up","yes"]
[14904,0,"chr1","+",202203736,202319781,"ENST00000255432",18,3406,"ENSG00000133067","LGR6","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0007186(G-protein coupled receptor signaling pathway);GO:0005886(plasma membrane);GO:0004871(signal transducer activity);GO:0007165(signal transduction);GO:0016055(Wnt signaling pathway);GO:0005887(integral component of plasma membrane);GO:0005515(protein binding);GO:0030335(positive regulation of cell migration);GO:0090263(positive regulation of canonical Wnt signaling pathway);GO:0004888(transmembrane signaling receptor activity);GO:0031982(vesicle);GO:0032588(trans-Golgi network membrane);GO:0030177(positive regulation of Wnt signaling pathway);GO:0042246(tissue regeneration);GO:1990523(bone regeneration)","NA","NA","NA","leucine rich repeat containing G protein-coupled receptor 6 [Source:HGNC Symbol;Acc:HGNC:19719]",{"v":1.720398,"d":"1.72"},{"v":0.293153,"d":"0.29"},{"v":5.86860103768339,"d":"5.87"},{"v":2.55301663339723,"d":"2.55"},{"v":0.000256193163571393,"d":"0.00"},{"v":0.00513105826498855,"d":"0.01"},"up","yes"]
[3281,"j","chr1","-",27611416,27635239,"MSTRG.298.1",12,3885,"MSTRG.298","FGR","NA","NA","NA","NA","NA",{"v":22.713709,"d":"22.71"},{"v":4.098741,"d":"4.10"},{"v":5.54163071050354,"d":"5.54"},{"v":2.47031057406788,"d":"2.47"},{"v":0.000258413430747697,"d":"0.00"},{"v":0.0051622990620988,"d":"0.01"},"up","yes"]
[141816,0,"chr3","+",152299683,152465780,"ENST00000463374",9,5092,"MSTRG.11286","MBNL1","GO:0003723(RNA binding);GO:0006397(mRNA processing);GO:0008380(RNA splicing);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0005813(centrosome);GO:0005515(protein binding);GO:0007399(nervous system development);GO:0043484(regulation of RNA splicing);GO:0010494(cytoplasmic stress granule);GO:0001701(in utero embryonic development);GO:0003725(double-stranded RNA binding);GO:0045445(myoblast differentiation);GO:0030326(embryonic limb morphogenesis);GO:0001069(regulatory region RNA binding)","NA","NA","NA","muscleblind like splicing regulator 1 [Source:HGNC Symbol;Acc:HGNC:6923]",{"v":0.12393,"d":"0.12"},{"v":0.817436,"d":"0.82"},{"v":0.151608199296336,"d":"0.15"},{"v":-2.72158031522871,"d":"-2.72"},{"v":0.00025873606351519,"d":"0.00"},{"v":0.0051622990620988,"d":"0.01"},"down","yes"]
[15074,0,"chr1","+",203795699,203852430,"ENST00000367212",20,3004,"MSTRG.1324","ZC3H11A","GO:0046872(metal ion binding);GO:0003723(RNA binding);GO:0006810(transport);GO:0051028(mRNA transport);GO:0005515(protein binding);GO:0005654(nucleoplasm);GO:0006369(termination of RNA polymerase II transcription);GO:0006405(RNA export from nucleus);GO:0031124(mRNA 3'-end processing);GO:0006406(mRNA export from nucleus);GO:0000346(transcription export complex);GO:0016973(poly(A)+ mRNA export from nucleus)","NA","NA","NA","zinc finger CCCH-type containing 11A [Source:HGNC Symbol;Acc:HGNC:29093]",{"v":1.285046,"d":"1.29"},{"v":7.704527,"d":"7.70"},{"v":0.166791030779696,"d":"0.17"},{"v":-2.5838863852269,"d":"-2.58"},{"v":0.000285806929924615,"d":"0.00"},{"v":0.0055677978309607,"d":"0.01"},"down","yes"]
[138101,0,"chr3","-",72749279,72848480,"ENST00000325599",11,2879,"ENSG00000144736","SHQ1","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0005515(protein binding);GO:1904874(positive regulation of telomerase RNA localization to Cajal body);GO:0043065(positive regulation of apoptotic process);GO:0051082(unfolded protein binding);GO:0000493(box H/ACA snoRNP assembly);GO:0022618(ribonucleoprotein complex assembly);GO:2000233(negative regulation of rRNA processing)","NA","NA","NA","SHQ1, H/ACA ribonucleoprotein assembly factor [Source:HGNC Symbol;Acc:HGNC:25543]",{"v":1.660926,"d":"1.66"},{"v":0.30472,"d":"0.30"},{"v":5.45066290364925,"d":"5.45"},{"v":2.44643169954989,"d":"2.45"},{"v":0.000438578224903581,"d":"0.00"},{"v":0.00771588545803939,"d":"0.01"},"up","yes"]
[81922,0,"chr17","+",32142466,32225727,"ENST00000358365",21,3297,"MSTRG.6663","RHOT1","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005525(GTP binding);GO:0007264(small GTPase mediated signal transduction);GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0016787(hydrolase activity);GO:0005509(calcium ion binding);GO:0003924(GTPase activity);GO:0005739(mitochondrion);GO:0005515(protein binding);GO:0005741(mitochondrial outer membrane);GO:0007005(mitochondrion organization);GO:0005886(plasma membrane);GO:0003674(molecular_function);GO:0005829(cytosol);GO:0051056(regulation of small GTPase mediated signal transduction);GO:0016579(protein deubiquitination);GO:0031307(integral component of mitochondrial outer membrane);GO:0019725(cellular homeostasis);GO:0097345(mitochondrial outer membrane permeabilization);GO:0047497(mitochondrion transport along microtubule);GO:0034640(establishment of mitochondrion localization by microtubule attachment);GO:0046928(regulation of neurotransmitter secretion);GO:1902513(regulation of organelle transport along microtubule);GO:0005622(intracellular)","04137(Mitophagy - animal)","K07870","EC:3.6.5.-","ras homolog family member T1 [Source:HGNC Symbol;Acc:HGNC:21168]",{"v":0.228887,"d":"0.23"},{"v":1.303165,"d":"1.30"},{"v":0.1756393089133,"d":"0.18"},{"v":-2.5093123318607,"d":"-2.51"},{"v":0.000631689772424255,"d":"0.00"},{"v":0.0102800174211634,"d":"0.01"},"down","yes"]
[192636,0,"chr9","+",111661335,111670246,"ENST00000374293",3,1491,"MSTRG.14898","GNG10","GO:0016020(membrane);GO:0007186(G-protein coupled receptor signaling pathway);GO:0004871(signal transducer activity);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0007165(signal transduction);GO:0005834(heterotrimeric G-protein complex);GO:0070062(extracellular exosome);GO:0003924(GTPase activity);GO:0071377(cellular response to glucagon stimulus)","04014(Ras signaling pathway);04371(Apelin signaling pathway);04151(PI3K-Akt signaling pathway);04062(Chemokine signaling pathway);04926(Relaxin signaling pathway);04724(Glutamatergic synapse);04727(GABAergic synapse);04725(Cholinergic synapse);04728(Dopaminergic synapse);04726(Serotonergic synapse);04723(Retrograde endocannabinoid signaling);04713(Circadian entrainment);05200(Pathways in cancer);05032(Morphine addiction);05034(Alcoholism);05167(Kaposi's sarcoma-associated herpesvirus infection)","K04545","NA","G protein subunit gamma 10 [Source:HGNC Symbol;Acc:HGNC:4402]",{"v":4.109417,"d":"4.11"},{"v":19.755901,"d":"19.76"},{"v":0.20800959672758,"d":"0.21"},{"v":-2.26527800482915,"d":"-2.27"},{"v":1.29867504946962E-3,"d":"0.00"},{"v":0.0179088006821889,"d":"0.02"},"down","yes"]
[74814,0,"chr16","+",68264530,68301819,"ENST00000219343",11,6251,"MSTRG.6064","SLC7A6","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0043231(intracellular membrane-bounded organelle);GO:0005886(plasma membrane);GO:0015297(antiporter activity);GO:0015171(amino acid transmembrane transporter activity);GO:0003333(amino acid transmembrane transport);GO:0050900(leukocyte migration);GO:1902475(L-alpha-amino acid transmembrane transport);GO:0016323(basolateral plasma membrane);GO:0006865(amino acid transport);GO:0005887(integral component of plasma membrane);GO:0006461(protein complex assembly);GO:0006520(cellular amino acid metabolic process);GO:0015179(L-amino acid transmembrane transporter activity);GO:0015807(L-amino acid transport)","NA","NA","NA","solute carrier family 7 member 6 [Source:HGNC Symbol;Acc:HGNC:11064]",{"v":0.139041,"d":"0.14"},{"v":0.682709,"d":"0.68"},{"v":0.20366071049305,"d":"0.20"},{"v":-2.29576040738672,"d":"-2.30"},{"v":0.00162710951865612,"d":"0.00"},{"v":0.0210974823821594,"d":"0.02"},"down","yes"]
[63810,0,"chr15","-",66499320,66504846,"ENST00000567229",8,2003,"MSTRG.5230","RPL4","GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0006412(translation);GO:0030529(intracellular ribonucleoprotein complex);GO:0003735(structural constituent of ribosome);GO:0005840(ribosome);GO:0005515(protein binding);GO:0005730(nucleolus);GO:0005925(focal adhesion);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0002181(cytoplasmic translation);GO:0006413(translational initiation);GO:0006364(rRNA processing);GO:0000184(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay);GO:0019083(viral transcription);GO:0005791(rough endoplasmic reticulum);GO:0006614(SRP-dependent cotranslational protein targeting to membrane);GO:0022625(cytosolic large ribosomal subunit)","03010(Ribosome)","NA","NA","ribosomal protein L4 [Source:HGNC Symbol;Acc:HGNC:10353]",{"v":2.031573,"d":"2.03"},{"v":0.464704,"d":"0.46"},{"v":4.3717570754717,"d":"4.37"},{"v":2.12821323729773,"d":"2.13"},{"v":0.00207226590909334,"d":"0.00"},{"v":0.0253547828877302,"d":"0.03"},"up","yes"]
[74724,0,"chr16","-",67987394,67999453,"ENST00000393847",11,1697,"MSTRG.6048","DPEP2","GO:0016020(membrane);GO:0046872(metal ion binding);GO:0016787(hydrolase activity);GO:0008233(peptidase activity);GO:0006508(proteolysis);GO:0008237(metallopeptidase activity);GO:0008235(metalloexopeptidase activity);GO:0008239(dipeptidyl-peptidase activity);GO:0016805(dipeptidase activity);GO:0031225(anchored component of membrane);GO:0008238(exopeptidase activity)","NA","NA","NA","dipeptidase 2 [Source:HGNC Symbol;Acc:HGNC:23028]",{"v":3.506275,"d":"3.51"},{"v":15.144895,"d":"15.14"},{"v":0.231515305982643,"d":"0.23"},{"v":-2.11082051852799,"d":"-2.11"},{"v":0.00267801924078915,"d":"0.00"},{"v":0.030732579425332,"d":"0.03"},"down","yes"]
[10670,0,"chr1","+",150926412,150964744,"ENST00000368969",22,4370,"MSTRG.932","SETDB1","GO:0005634(nucleus);GO:0043231(intracellular membrane-bounded organelle);GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0008168(methyltransferase activity);GO:0016740(transferase activity);GO:0032259(methylation);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0016569(covalent chromatin modification);GO:0003677(DNA binding);GO:0005886(plasma membrane);GO:0005694(chromosome);GO:0005515(protein binding);GO:0018024(histone-lysine N-methyltransferase activity);GO:0034968(histone lysine methylation);GO:0007265(Ras protein signal transduction);GO:0003682(chromatin binding);GO:1990841(promoter-specific chromatin binding);GO:0090309(positive regulation of methylation-dependent chromatin silencing);GO:0033273(response to vitamin);GO:0045471(response to ethanol)","00310(Lysine degradation);04550(Signaling pathways regulating pluripotency of stem cells)","K11421","EC:2.1.1.43","SET domain bifurcated 1 [Source:HGNC Symbol;Acc:HGNC:10761]",{"v":0.214589,"d":"0.21"},{"v":0.931355,"d":"0.93"},{"v":0.230405162370954,"d":"0.23"},{"v":-2.11775505326539,"d":"-2.12"},{"v":0.00336132004605672,"d":"0.00"},{"v":0.0366369206766706,"d":"0.04"},"down","yes"]
[88755,0,"chr17","+",78168611,78172719,"ENST00000588282",3,1553,"MSTRG.7274","SYNGR2","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005515(protein binding);GO:0031410(cytoplasmic vesicle);GO:0008021(synaptic vesicle);GO:0070062(extracellular exosome);GO:0030672(synaptic vesicle membrane);GO:0031594(neuromuscular junction)","NA","NA","NA","synaptogyrin 2 [Source:HGNC Symbol;Acc:HGNC:11499]",{"v":0.660845,"d":"0.66"},{"v":2.770689,"d":"2.77"},{"v":0.238512875317295,"d":"0.24"},{"v":-2.06786094750335,"d":"-2.07"},{"v":0.00420741261099195,"d":"0.00"},{"v":0.0433059871217976,"d":"0.04"},"down","yes"]
[198202,0,"chrX","+",71910818,72153286,"ENST00000633930",8,13660,"ENSG00000204131","NHSL2","GO:0030154(cell differentiation)","NA","NA","NA","NHS like 2 [Source:HGNC Symbol;Acc:HGNC:33737]",{"v":1.379826,"d":"1.38"},{"v":5.313093,"d":"5.31"},{"v":0.259702963979738,"d":"0.26"},{"v":-1.94506561535518,"d":"-1.95"},{"v":0.00524866569855153,"d":"0.01"},{"v":0.0507233462529568,"d":"0.05"},"down","yes"]
[78054,"j","chr17","+",4710600,4721500,"MSTRG.6331.4",15,2132,"MSTRG.6331","ARRB2","NA","NA","NA","NA","NA",{"v":6.51104,"d":"6.51"},{"v":1.905943,"d":"1.91"},{"v":3.41617771360424,"d":"3.42"},{"v":1.77238302761257,"d":"1.77"},{"v":7.25707835979019E-3,"d":"0.01"},{"v":0.0648073974455683,"d":"0.06"},"up","yes"]
[30752,0,"chr11","-",64316460,64317487,"ENST00000535750",3,823,"MSTRG.2507","TRMT112","GO:0005515(protein binding);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0043234(protein complex);GO:0031167(rRNA methylation);GO:0070476(rRNA (guanine-N7)-methylation);GO:0030488(tRNA methylation);GO:0032259(methylation);GO:0006415(translational termination);GO:0008276(protein methyltransferase activity);GO:0018364(peptidyl-glutamine methylation)","NA","NA","NA","tRNA methyltransferase subunit 11-2 [Source:HGNC Symbol;Acc:HGNC:26940]",{"v":1.565576,"d":"1.57"},{"v":5.833172,"d":"5.83"},{"v":0.268391880095427,"d":"0.27"},{"v":-1.89758706985919,"d":"-1.90"},{"v":0.0085268652073898,"d":"0.01"},{"v":0.0725818039283833,"d":"0.07"},"down","yes"]
[185955,0,"chr8","+",99868057,99877580,"ENST00000493587",3,3485,"MSTRG.14483","VPS13B","GO:0006810(transport);GO:0015031(protein transport)","NA","NA","NA","vacuolar protein sorting 13 homolog B [Source:HGNC Symbol;Acc:HGNC:2183]",{"v":1.715011,"d":"1.72"},{"v":0.517769,"d":"0.52"},{"v":3.31230915717241,"d":"3.31"},{"v":1.72783733428169,"d":"1.73"},{"v":0.00969718842657923,"d":"0.01"},{"v":0.07948828345728,"d":"0.08"},"up","yes"]
[44625,0,"chr12","-",76049146,76084685,"ENST00000549596",13,1838,"MSTRG.3567","NAP1L1","GO:0005634(nucleus);GO:0003723(RNA binding);GO:0016020(membrane);GO:0006334(nucleosome assembly);GO:0005515(protein binding);GO:0042470(melanosome);GO:0008284(positive regulation of cell proliferation);GO:0006260(DNA replication)","NA","NA","NA","nucleosome assembly protein 1 like 1 [Source:HGNC Symbol;Acc:HGNC:7637]",{"v":30.645121,"d":"30.65"},{"v":9.745737,"d":"9.75"},{"v":3.14446418982987,"d":"3.14"},{"v":1.65281420580686,"d":"1.65"},{"v":0.0110055279663795,"d":"0.01"},{"v":0.0869297398863391,"d":"0.09"},"up","yes"]
[133463,0,"chr3","+",12484511,12539623,"ENST00000473755",11,3918,"MSTRG.10663","TSEN2","GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0005813(centrosome);GO:0000213(tRNA-intron endonuclease activity);GO:0006388(tRNA splicing, via endonucleolytic cleavage and ligation);GO:0090501(RNA phosphodiester bond hydrolysis);GO:0090502(RNA phosphodiester bond hydrolysis, endonucleolytic);GO:0000214(tRNA-intron endonuclease complex);GO:0006397(mRNA processing);GO:0005634(nucleus);GO:0008033(tRNA processing);GO:0016829(lyase activity);GO:0005515(protein binding);GO:0005730(nucleolus);GO:0000379(tRNA-type intron splice site recognition and cleavage);GO:0090305(nucleic acid phosphodiester bond hydrolysis);GO:0004519(endonuclease activity)","NA","NA","NA","tRNA splicing endonuclease subunit 2 [Source:HGNC Symbol;Acc:HGNC:28422]",{"v":0.609264,"d":"0.61"},{"v":0.186197,"d":"0.19"},{"v":3.27214724189971,"d":"3.27"},{"v":1.7102376689334,"d":"1.71"},{"v":0.0125748555239299,"d":"0.01"},{"v":0.0952559617230013,"d":"0.10"},"up","yes"]
[186863,0,"chr8","-",123248456,123274495,"ENST00000395571",4,5108,"MSTRG.14542","ZHX1","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0005654(nucleoplasm);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0005515(protein binding);GO:0030154(cell differentiation);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0003714(transcription corepressor activity);GO:0045892(negative regulation of transcription, DNA-templated);GO:0046982(protein heterodimerization activity)","NA","NA","NA","zinc fingers and homeoboxes 1 [Source:HGNC Symbol;Acc:HGNC:12871]",{"v":0.336172,"d":"0.34"},{"v":1.125574,"d":"1.13"},{"v":0.29866716892892,"d":"0.30"},{"v":-1.7433894371739,"d":"-1.74"},{"v":0.0139268844084007,"d":"0.01"},{"v":0.101939892913103,"d":"0.10"},"down","yes"]
[95987,0,"chr19","-",8520797,8577577,"ENST00000613525",29,4296,"MSTRG.7774","MYO1F","GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0003774(motor activity);GO:0016459(myosin complex);GO:0003779(actin binding);GO:0005516(calmodulin binding);GO:0008150(biological_process);GO:0016461(unconventional myosin complex)","NA","NA","NA","myosin IF [Source:HGNC Symbol;Acc:HGNC:7600]",{"v":32.391804,"d":"32.39"},{"v":103.174049,"d":"103.17"},{"v":0.31395301739103,"d":"0.31"},{"v":-1.67137941681639,"d":"-1.67"},{"v":0.0159479822683595,"d":"0.02"},{"v":0.112288191091186,"d":"0.11"},"down","yes"]
[98658,0,"chr19","+",18571855,18575229,"ENST00000596273",6,764,"MSTRG.8003","UBA52","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005783(endoplasmic reticulum);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0030529(intracellular ribonucleoprotein complex);GO:0005765(lysosomal membrane);GO:0003735(structural constituent of ribosome);GO:0006412(translation);GO:0005840(ribosome);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0044322(endoplasmic reticulum quality control compartment);GO:0005615(extracellular space);GO:0038095(Fc-epsilon receptor signaling pathway);GO:0016567(protein ubiquitination);GO:0005789(endoplasmic reticulum membrane);GO:0006977(DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest);GO:0070062(extracellular exosome);GO:0034220(ion transmembrane transport);GO:0044267(cellular protein metabolic process);GO:0061024(membrane organization);GO:0016197(endosomal transport);GO:0019058(viral life cycle);GO:0075733(intracellular transport of virus);GO:0010008(endosome membrane);GO:0043657(host cell);GO:0000165(MAPK cascade);GO:0000209(protein polyubiquitination);GO:0002223(stimulatory C-type lectin receptor signaling pathway);GO:0010972(negative regulation of G2/M transition of mitotic cell cycle);GO:0016579(protein deubiquitination);GO:0031145(anaphase-promoting complex-dependent catabolic process);GO:0031146(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process);GO:0033209(tumor necrosis factor-mediated signaling pathway);GO:0038061(NIK/NF-kappaB signaling);GO:0043161(proteasome-mediated ubiquitin-dependent protein catabolic process);GO:0043488(regulation of mRNA stability);GO:0050852(T cell receptor signaling pathway);GO:0051437(positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition);GO:0055085(transmembrane transport);GO:0060071(Wnt signaling pathway, planar cell polarity pathway);GO:0061418(regulation of transcription from RNA polymerase II promoter in response to hypoxia);GO:0090090(negative regulation of canonical Wnt signaling pathway);GO:0090263(positive regulation of canonical Wnt signaling pathway);GO:1902036(regulation of hematopoietic stem cell differentiation);GO:0045087(innate immune response);GO:0000086(G2/M transition of mitotic cell cycle);GO:0036297(interstrand cross-link repair);GO:0006457(protein folding);GO:0002755(MyD88-dependent toll-like receptor signaling pathway);GO:0002756(MyD88-independent toll-like receptor signaling pathway);GO:0007249(I-kappaB kinase/NF-kappaB signaling);GO:0035666(TRIF-dependent toll-like receptor signaling pathway);GO:0051436(negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle);GO:1904380(endoplasmic reticulum mannose trimming);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:1901796(regulation of signal transduction by p53 class mediator);GO:0031982(vesicle);GO:0006413(translational initiation);GO:0006464(cellular protein modification process);GO:0030666(endocytic vesicle membrane);GO:0005741(mitochondrial outer membrane);GO:0006364(rRNA processing);GO:0007219(Notch signaling pathway);GO:0016055(Wnt signaling pathway);GO:0042787(protein ubiquitination involved in ubiquitin-dependent protein catabolic process);GO:0038128(ERBB2 signaling pathway);GO:0007254(JNK cascade);GO:0043065(positive regulation of apoptotic process);GO:0010803(regulation of tumor necrosis factor-mediated signaling pathway);GO:0043066(negative regulation of apoptotic process);GO:0043123(positive regulation of I-kappaB kinase/NF-kappaB signaling);GO:0051092(positive regulation of NF-kappaB transcription factor activity);GO:0051403(stress-activated MAPK cascade);GO:0070423(nucleotide-binding oligomerization domain containing signaling pathway);GO:0019985(translesion synthesis);GO:0032480(negative regulation of type I interferon production);GO:0042059(negative regulation of epidermal growth factor receptor signaling pathway);GO:0030512(negative regulation of transforming growth factor beta receptor signaling pathway);GO:0000184(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay);GO:0005978(glycogen biosynthetic process);GO:0019083(viral transcription);GO:0006283(transcription-coupled nucleotide-excision repair);GO:0008543(fibroblast growth factor receptor signaling pathway);GO:0000187(activation of MAPK activity);GO:0016236(macroautophagy);GO:0042276(error-prone translesion synthesis);GO:0035635(entry of bacterium into host cell);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0006614(SRP-dependent cotranslational protein targeting to membrane);GO:0042769(DNA damage response, detection of DNA damage);GO:0007179(transforming growth factor beta receptor signaling pathway);GO:0006879(cellular iron ion homeostasis);GO:0006296(nucleotide-excision repair, DNA incision, 5'-to lesion);GO:0033683(nucleotide-excision repair, DNA incision);GO:0070911(global genome nucleotide-excision repair);GO:0000715(nucleotide-excision repair, DNA damage recognition);GO:0000717(nucleotide-excision repair, DNA duplex unwinding);GO:0006294(nucleotide-excision repair, preincision complex assembly);GO:0006297(nucleotide-excision repair, DNA gap filling);GO:0019068(virion assembly);GO:0032479(regulation of type I interferon production);GO:0045742(positive regulation of epidermal growth factor receptor signaling pathway);GO:0060544(regulation of necroptotic process);GO:0070987(error-free translesion synthesis)","03010(Ribosome)","NA","NA","ubiquitin A-52 residue ribosomal protein fusion product 1 [Source:HGNC Symbol;Acc:HGNC:12458]",{"v":8.367007,"d":"8.37"},{"v":2.832041,"d":"2.83"},{"v":2.95440885213173,"d":"2.95"},{"v":1.56286949032994,"d":"1.56"},{"v":0.0174294091694443,"d":"0.02"},{"v":0.118862855975227,"d":"0.12"},"up","yes"]
[124512,0,"chr20","+",49278178,49289260,"ENST00000371743",5,1008,"MSTRG.9812","ZFAS1","NA","NA","NA","NA","ZNFX1 antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:33101]",{"v":10.980701,"d":"10.98"},{"v":3.853307,"d":"3.85"},{"v":2.84968236374626,"d":"2.85"},{"v":1.51080112005409,"d":"1.51"},{"v":0.0204736171902947,"d":"0.02"},{"v":0.132948679042538,"d":"0.13"},"up","yes"]
[163483,0,"chr6","+",26445538,26452161,"ENST00000483179",7,1238,"MSTRG.12749","BTN3A3","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005886(plasma membrane);GO:0002376(immune system process);GO:0002250(adaptive immune response);GO:0002456(T cell mediated immunity)","NA","NA","NA","butyrophilin subfamily 3 member A3 [Source:HGNC Symbol;Acc:HGNC:1140]",{"v":2.295262,"d":"2.30"},{"v":0.809765,"d":"0.81"},{"v":2.83447913900947,"d":"2.83"},{"v":1.50308365135584,"d":"1.50"},{"v":0.0245850590545417,"d":"0.02"},{"v":0.151498715821465,"d":"0.15"},"up","yes"]
[78349,0,"chr17","-",5529895,5584512,"ENST00000571307",14,4050,"MSTRG.6364","NLRP1","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0042981(regulation of apoptotic process);GO:0005515(protein binding);GO:0006915(apoptotic process);GO:0006954(inflammatory response);GO:0002376(immune system process);GO:0045087(innate immune response);GO:0005622(intracellular);GO:0016032(viral process);GO:0019899(enzyme binding);GO:0019904(protein domain specific binding);GO:0008656(cysteine-type endopeptidase activator activity involved in apoptotic process);GO:0006919(activation of cysteine-type endopeptidase activity involved in apoptotic process);GO:0042742(defense response to bacterium);GO:0050727(regulation of inflammatory response);GO:0051402(neuron apoptotic process);GO:0072558(NLRP1 inflammasome complex);GO:0050718(positive regulation of interleukin-1 beta secretion);GO:0061702(inflammasome complex);GO:0032495(response to muramyl dipeptide);GO:1904784(NLRP1 inflammasome complex assembly);GO:0097110(scaffold protein binding);GO:0043025(neuronal cell body);GO:0043234(protein complex)","04621(NOD-like receptor signaling pathway)","NA","NA","NLR family pyrin domain containing 1 [Source:HGNC Symbol;Acc:HGNC:14374]",{"v":1.180626,"d":"1.18"},{"v":3.461962,"d":"3.46"},{"v":0.341028006662118,"d":"0.34"},{"v":-1.55203787055467,"d":"-1.55"},{"v":0.0267006114755738,"d":"0.03"},{"v":0.159969230419903,"d":"0.16"},"down","yes"]
[146652,"i","chr4",".",36345835,36347048,"MSTRG.11560.1",1,1214,"MSTRG.11560","AC104078.2","NA","NA","NA","NA","NA",{"v":5.814555,"d":"5.81"},{"v":2.170578,"d":"2.17"},{"v":2.67880490818575,"d":"2.68"},{"v":1.42158951651374,"d":"1.42"},{"v":0.0296029038006683,"d":"0.03"},{"v":0.17183452996853,"d":"0.17"},"up","yes"]
[138718,0,"chr3","-",101681091,101686712,"ENST00000464595",5,668,"MSTRG.11096","RPL24","GO:0005737(cytoplasm);GO:0003723(RNA binding);GO:0016020(membrane);GO:0006412(translation);GO:0030529(intracellular ribonucleoprotein complex);GO:0005840(ribosome);GO:0003735(structural constituent of ribosome);GO:0000027(ribosomal large subunit assembly);GO:0005829(cytosol);GO:0045296(cadherin binding);GO:0070062(extracellular exosome);GO:0005515(protein binding);GO:0006413(translational initiation);GO:0006364(rRNA processing);GO:0000184(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay);GO:0019083(viral transcription);GO:0006614(SRP-dependent cotranslational protein targeting to membrane);GO:0022625(cytosolic large ribosomal subunit);GO:1902626(assembly of large subunit precursor of preribosome);GO:0007093(mitotic cell cycle checkpoint);GO:0010458(exit from mitosis);GO:0021554(optic nerve development);GO:0031290(retinal ganglion cell axon guidance);GO:0060041(retina development in camera-type eye)","03010(Ribosome)","NA","NA","ribosomal protein L24 [Source:HGNC Symbol;Acc:HGNC:10325]",{"v":170.728302,"d":"170.73"},{"v":65.891098,"d":"65.89"},{"v":2.59106779492429,"d":"2.59"},{"v":1.37354676392461,"d":"1.37"},{"v":0.031832860018034,"d":"0.03"},{"v":0.179965614054389,"d":"0.18"},"up","yes"]
[15151,0,"chr1","+",204516383,204532650,"ENST00000470797",5,909,"ENSG00000198625","MDM4","GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0043066(negative regulation of apoptotic process);GO:0016567(protein ubiquitination);GO:0008270(zinc ion binding);GO:0005515(protein binding);GO:0071157(negative regulation of cell cycle arrest);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0061630(ubiquitin protein ligase activity);GO:0006977(DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest);GO:0005654(nucleoplasm);GO:0050821(protein stabilization);GO:0016579(protein deubiquitination);GO:0008283(cell proliferation);GO:0019899(enzyme binding);GO:1901796(regulation of signal transduction by p53 class mediator);GO:0008285(negative regulation of cell proliferation);GO:0042177(negative regulation of protein catabolic process);GO:0006461(protein complex assembly);GO:0030330(DNA damage response, signal transduction by p53 class mediator);GO:0045023(G0 to G1 transition);GO:0071456(cellular response to hypoxia)","04115(p53 signaling pathway);05206(MicroRNAs in cancer)","NA","NA","MDM4, p53 regulator [Source:HGNC Symbol;Acc:HGNC:6974]",{"v":2.168779,"d":"2.17"},{"v":0.790856,"d":"0.79"},{"v":2.74231844988215,"d":"2.74"},{"v":1.45539611283466,"d":"1.46"},{"v":0.0338688130133041,"d":"0.03"},{"v":0.186614916735556,"d":"0.19"},"up","yes"]
[12413,0,"chr1","+",158845901,158849506,"ENST00000438394",3,582,"MSTRG.1101","MNDA","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005730(nucleolus);GO:0005654(nucleoplasm);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0006974(cellular response to DNA damage stimulus);GO:0005576(extracellular region);GO:0070062(extracellular exosome);GO:0043065(positive regulation of apoptotic process);GO:0043312(neutrophil degranulation);GO:1904813(ficolin-1-rich granule lumen);GO:0050853(B cell receptor signaling pathway);GO:0035578(azurophil granule lumen);GO:0006968(cellular defense response);GO:0030889(negative regulation of B cell proliferation)","NA","NA","NA","myeloid cell nuclear differentiation antigen [Source:HGNC Symbol;Acc:HGNC:7183]",{"v":1.318653,"d":"1.32"},{"v":3.814753,"d":"3.81"},{"v":0.345671921615895,"d":"0.35"},{"v":-1.53252467436684,"d":"-1.53"},{"v":0.0367949889508123,"d":"0.04"},{"v":0.196870937666082,"d":"0.20"},"down","yes"]
[18843,0,"chr10","-",17215196,17229985,"ENST00000605833",3,918,"MSTRG.1596","VIM-AS1","NA","NA","NA","NA","VIM antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:44879]",{"v":3.496601,"d":"3.50"},{"v":9.532022,"d":"9.53"},{"v":0.366826786593652,"d":"0.37"},{"v":-1.44682910296961,"d":"-1.45"},{"v":0.0397162816678796,"d":"0.04"},{"v":0.207385216638165,"d":"0.21"},"down","yes"]
[385,0,"chr1","-",1335276,1349350,"ENST00000378888",15,3239,"ENSG00000107404","DVL1","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0035556(intracellular signal transduction);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0007275(multicellular organism development);GO:0016055(Wnt signaling pathway);GO:0031410(cytoplasmic vesicle);GO:0098793(presynapse);GO:0042802(identical protein binding);GO:0006366(transcription from RNA polymerase II promoter);GO:0090090(negative regulation of canonical Wnt signaling pathway);GO:0019899(enzyme binding);GO:0045893(positive regulation of transcription, DNA-templated);GO:0050821(protein stabilization);GO:0060070(canonical Wnt signaling pathway);GO:0099054(presynapse assembly);GO:1905386(positive regulation of protein localization to presynapse);GO:0016328(lateral plasma membrane);GO:0005109(frizzled binding);GO:0019901(protein kinase binding);GO:0001505(regulation of neurotransmitter levels);GO:0006469(negative regulation of protein kinase activity);GO:0007269(neurotransmitter secretion);GO:0007528(neuromuscular junction development);GO:0021915(neural tube development);GO:0030177(positive regulation of Wnt signaling pathway);GO:0032091(negative regulation of protein binding);GO:0032436(positive regulation of proteasomal ubiquitin-dependent protein catabolic process);GO:0034504(protein localization to nucleus);GO:0043113(receptor clustering);GO:0048813(dendrite morphogenesis);GO:0050808(synapse organization);GO:0060071(Wnt signaling pathway, planar cell polarity pathway);GO:0090179(planar cell polarity pathway involved in neural tube closure);GO:1903827(regulation of cellular protein localization);GO:1904886(beta-catenin destruction complex disassembly);GO:0030426(growth cone);GO:0043005(neuron projection);GO:0045202(synapse);GO:0008013(beta-catenin binding);GO:0048365(Rac GTPase binding);GO:0001932(regulation of protein phosphorylation);GO:0001933(negative regulation of protein phosphorylation);GO:0001934(positive regulation of protein phosphorylation);GO:0007409(axonogenesis);GO:0007411(axon guidance);GO:0010976(positive regulation of neuron projection development);GO:0022007(convergent extension involved in neural plate elongation);GO:0031122(cytoplasmic microtubule organization);GO:0035176(social behavior);GO:0035372(protein localization to microtubule);GO:0048668(collateral sprouting);GO:0048675(axon extension);GO:0060029(convergent extension involved in organogenesis);GO:0060134(prepulse inhibition);GO:0060997(dendritic spine morphogenesis);GO:0071340(skeletal muscle acetylcholine-gated channel clustering);GO:0090103(cochlea morphogenesis);GO:0090263(positive regulation of canonical Wnt signaling pathway);GO:2000463(positive regulation of excitatory postsynaptic potential);GO:0005874(microtubule);GO:0014069(postsynaptic density);GO:0015630(microtubule cytoskeleton);GO:0030136(clathrin-coated vesicle);GO:0030424(axon);GO:0030425(dendrite);GO:0043025(neuronal cell body);GO:0043197(dendritic spine);GO:1990909(Wnt signalosome);GO:0005622(intracellular)","04310(Wnt signaling pathway);04330(Notch signaling pathway);04390(Hippo signaling pathway);04150(mTOR signaling pathway);04550(Signaling pathways regulating pluripotency of stem cells);04916(Melanogenesis);05200(Pathways in cancer);05225(Hepatocellular carcinoma);05226(Gastric cancer);05217(Basal cell carcinoma);05224(Breast cancer);05166(HTLV-I infection);05165(Human papillomavirus infection)","K02353","NA","dishevelled segment polarity protein 1 [Source:HGNC Symbol;Acc:HGNC:3084]",{"v":0.414796,"d":"0.41"},{"v":1.121045,"d":"1.12"},{"v":0.370008340432364,"d":"0.37"},{"v":-1.43437030370039,"d":"-1.43"},{"v":0.0459300978594356,"d":"0.05"},{"v":0.227589071771122,"d":"0.23"},"down","yes"]
[183366,0,"chr8","-",41929479,42051987,"ENST00000265713",17,9153,"MSTRG.14327","KAT6A","GO:0005634(nucleus);GO:0016607(nuclear speck);GO:0046872(metal ion binding);GO:0005730(nucleolus);GO:0005829(cytosol);GO:0016740(transferase activity);GO:0003713(transcription coactivator activity);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0016569(covalent chromatin modification);GO:0003677(DNA binding);GO:0016746(transferase activity, transferring acyl groups);GO:0006334(nucleosome assembly);GO:0000786(nucleosome);GO:0008270(zinc ion binding);GO:0005515(protein binding);GO:0016747(transferase activity, transferring acyl groups other than amino-acyl groups);GO:0004402(histone acetyltransferase activity);GO:0045893(positive regulation of transcription, DNA-templated);GO:0005654(nucleoplasm);GO:0070776(MOZ/MORF histone acetyltransferase complex);GO:0043966(histone H3 acetylation);GO:0048513(animal organ development);GO:0008134(transcription factor binding);GO:0045892(negative regulation of transcription, DNA-templated);GO:1901796(regulation of signal transduction by p53 class mediator);GO:0016605(PML body);GO:0006323(DNA packaging);GO:0090398(cellular senescence);GO:0030099(myeloid cell differentiation);GO:0016407(acetyltransferase activity);GO:0006473(protein acetylation);GO:0016573(histone acetylation)","04550(Signaling pathways regulating pluripotency of stem cells)","K11305","EC:2.3.1.48","lysine acetyltransferase 6A [Source:HGNC Symbol;Acc:HGNC:13013]",{"v":4.090474,"d":"4.09"},{"v":1.718247,"d":"1.72"},{"v":2.38060884145295,"d":"2.38"},{"v":1.25133059042954,"d":"1.25"},{"v":0.0493460135412585,"d":"0.05"},{"v":0.2381271600471,"d":"0.24"},"up","yes"]
[168941,0,"chr6","+",125781161,125931111,"ENST00000368357",17,5521,"ENSG00000111912","NCOA7","GO:0005634(nucleus);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0005515(protein binding);GO:0030374(ligand-dependent nuclear receptor transcription coactivator activity);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0005622(intracellular);GO:0035257(nuclear hormone receptor binding);GO:1900408(negative regulation of cellular response to oxidative stress);GO:1902083(negative regulation of peptidyl-cysteine S-nitrosylation);GO:1903204(negative regulation of oxidative stress-induced neuron death)","NA","NA","NA","nuclear receptor coactivator 7 [Source:HGNC Symbol;Acc:HGNC:21081]",{"v":1.884781,"d":"1.88"},{"v":0.79539,"d":"0.80"},{"v":2.36963125007858,"d":"2.37"},{"v":1.24466257175059,"d":"1.24"},{"v":0.0526633860814469,"d":"0.05"},{"v":0.248601062239795,"d":"0.25"},"up","no"]
[166103,0,"chr6","-",43012094,43013968,"ENST00000244711",4,1089,"MSTRG.13053","MEA1","GO:0005515(protein binding);GO:0007275(multicellular organism development);GO:0030154(cell differentiation);GO:0007283(spermatogenesis);GO:0008584(male gonad development);GO:0005737(cytoplasm)","NA","NA","NA","male-enhanced antigen 1 [Source:HGNC Symbol;Acc:HGNC:6986]",{"v":3.864402,"d":"3.86"},{"v":1.625088,"d":"1.63"},{"v":2.37796476252363,"d":"2.38"},{"v":1.24972733690482,"d":"1.25"},{"v":0.0563100357773272,"d":"0.06"},{"v":0.259299977281096,"d":"0.26"},"up","no"]
[34875,0,"chr11","-",108472105,108498432,"ENST00000323468",8,4312,"ENSG00000178202","KDELC2","GO:0005783(endoplasmic reticulum);GO:0005788(endoplasmic reticulum lumen);GO:0003674(molecular_function);GO:0008150(biological_process);GO:0005575(cellular_component);GO:0046527(glucosyltransferase activity);GO:0006664(glycolipid metabolic process)","NA","NA","NA","KDEL motif containing 2 [Source:HGNC Symbol;Acc:HGNC:28496]",{"v":0.629469,"d":"0.63"},{"v":0.266569,"d":"0.27"},{"v":2.36137360308213,"d":"2.36"},{"v":1.23962631461747,"d":"1.24"},{"v":0.0602417170617219,"d":"0.06"},{"v":0.271597788730743,"d":"0.27"},"up","no"]
[10685,0,"chr1","-",150965173,150975004,"ENST00000368954",11,2505,"MSTRG.933","CERS2","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005783(endoplasmic reticulum);GO:0005634(nucleus);GO:0003677(DNA binding);GO:0006629(lipid metabolic process);GO:0005789(endoplasmic reticulum membrane);GO:0005515(protein binding);GO:0031965(nuclear membrane);GO:0030148(sphingolipid biosynthetic process);GO:0046513(ceramide biosynthetic process);GO:0050291(sphingosine N-acyltransferase activity);GO:0048681(negative regulation of axon regeneration);GO:1900148(negative regulation of Schwann cell migration);GO:1905045(negative regulation of Schwann cell proliferation involved in axon regeneration)","00600(Sphingolipid metabolism);04071(Sphingolipid signaling pathway)","K04710","EC:2.3.1.24","ceramide synthase 2 [Source:HGNC Symbol;Acc:HGNC:14076]",{"v":18.963032,"d":"18.96"},{"v":46.358479,"d":"46.36"},{"v":0.409052074378885,"d":"0.41"},{"v":-1.28964357772053,"d":"-1.29"},{"v":0.0633409353463391,"d":"0.06"},{"v":0.279821194025597,"d":"0.28"},"down","no"]
[175097,"j","chr7","+",74773990,74789402,"MSTRG.13717.2",10,1882,"MSTRG.13717","NCF1","NA","NA","NA","NA","NA",{"v":11.437125,"d":"11.44"},{"v":27.576111,"d":"27.58"},{"v":0.414747569010003,"d":"0.41"},{"v":-1.26969456985449,"d":"-1.27"},{"v":0.0680596748953421,"d":"0.07"},{"v":0.293650732132712,"d":"0.29"},"down","no"]
[81192,0,"chr17","-",28546707,28552668,"ENST00000335765",5,1424,"MSTRG.6564","UNC119","GO:0006810(transport);GO:0005737(cytoplasm);GO:0015031(protein transport);GO:0007601(visual perception);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0050896(response to stimulus);GO:0000922(spindle pole);GO:0005813(centrosome);GO:0005815(microtubule organizing center);GO:0005819(spindle);GO:0008289(lipid binding);GO:0006897(endocytosis);GO:0051233(spindle midzone);GO:0030182(neuron differentiation);GO:0042953(lipoprotein transport);GO:0007268(chemical synaptic transmission);GO:0007602(phototransduction);GO:0000281(mitotic cytokinesis);GO:0005829(cytosol);GO:0061098(positive regulation of protein tyrosine kinase activity);GO:0045171(intercellular bridge);GO:1900186(negative regulation of clathrin-dependent endocytosis);GO:2001287(negative regulation of caveolin-mediated endocytosis)","NA","NA","NA","unc-119 lipid binding chaperone [Source:HGNC Symbol;Acc:HGNC:12565]",{"v":7.5375,"d":"7.54"},{"v":17.804867,"d":"17.80"},{"v":0.423339303798225,"d":"0.42"},{"v":-1.24011365687485,"d":"-1.24"},{"v":0.0757004567080898,"d":"0.08"},{"v":0.312763649813188,"d":"0.31"},"down","no"]
[162415,"j","chr6","-",2832338,2842009,"MSTRG.12628.2",8,2876,"MSTRG.12628","SERPINB1","NA","NA","NA","NA","NA",{"v":0.431294,"d":"0.43"},{"v":1.035786,"d":"1.04"},{"v":0.41639296148046,"d":"0.42"},{"v":-1.26398241271271,"d":"-1.26"},{"v":0.0801227393040731,"d":"0.08"},{"v":0.324850935720555,"d":"0.32"},"down","no"]
[94774,0,"chr19","-",3054023,3062410,"ENST00000585557",5,491,"MSTRG.7654","AES","GO:0005634(nucleus);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0005515(protein binding);GO:0016055(Wnt signaling pathway);GO:0003714(transcription corepressor activity);GO:0090090(negative regulation of canonical Wnt signaling pathway);GO:0010629(negative regulation of gene expression);GO:0007275(multicellular organism development);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0045892(negative regulation of transcription, DNA-templated);GO:0009887(animal organ morphogenesis);GO:0032091(negative regulation of protein binding);GO:0070555(response to interleukin-1);GO:0060761(negative regulation of response to cytokine stimulus);GO:0001501(skeletal system development);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0031668(cellular response to extracellular stimulus);GO:0040008(regulation of growth);GO:2000210(positive regulation of anoikis)","NA","NA","NA","amino-terminal enhancer of split [Source:HGNC Symbol;Acc:HGNC:307]",{"v":3.426124,"d":"3.43"},{"v":1.526541,"d":"1.53"},{"v":2.24437077025773,"d":"2.24"},{"v":1.1663110289887,"d":"1.17"},{"v":0.0845744473360473,"d":"0.08"},{"v":0.335484519242188,"d":"0.34"},"up","no"]
[12684,0,"chr1","+",160796074,160828261,"ENST00000368037",10,2485,"MSTRG.1124","LY9","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0007155(cell adhesion);GO:0005886(plasma membrane);GO:0002376(immune system process);GO:0045087(innate immune response);GO:0002250(adaptive immune response);GO:0003674(molecular_function);GO:0072540(T-helper 17 cell lineage commitment);GO:0032740(positive regulation of interleukin-17 production);GO:0009986(cell surface)","NA","NA","NA","lymphocyte antigen 9 [Source:HGNC Symbol;Acc:HGNC:6730]",{"v":2.427645,"d":"2.43"},{"v":1.142559,"d":"1.14"},{"v":2.12474366750426,"d":"2.12"},{"v":1.08728880269658,"d":"1.09"},{"v":0.0889763393296585,"d":"0.09"},{"v":0.346669179265292,"d":"0.35"},"up","no"]
[162623,"j","chr6","-",6144072,6321204,"MSTRG.12650.1",16,4103,"MSTRG.12650","F13A1","NA","NA","NA","NA","NA",{"v":13.184017,"d":"13.18"},{"v":29.385569,"d":"29.39"},{"v":0.44865617541726,"d":"0.45"},{"v":-1.15631782595224,"d":"-1.16"},{"v":0.0967807061168101,"d":"0.10"},{"v":0.366631974908075,"d":"0.37"},"down","no"]
[72137,0,"chr16","-",31083437,31089628,"ENST00000486499",2,5489,"MSTRG.5879","PRSS53","GO:0016787(hydrolase activity);GO:0008233(peptidase activity);GO:0006508(proteolysis);GO:0005576(extracellular region);GO:0004252(serine-type endopeptidase activity);GO:0008236(serine-type peptidase activity);GO:0005737(cytoplasm)","NA","NA","NA","protease, serine 53 [Source:HGNC Symbol;Acc:HGNC:34407]",{"v":0.554576,"d":"0.55"},{"v":0.263415,"d":"0.26"},{"v":2.10533189074274,"d":"2.11"},{"v":1.07404768193092,"d":"1.07"},{"v":0.0993777565620112,"d":"0.10"},{"v":0.372713528343033,"d":"0.37"},"up","no"]
[16771,0,"chr1","+",228208130,228378874,"ENST00000570156",116,26925,"ENSG00000154358","OBSCN","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0005829(cytosol);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0005886(plasma membrane);GO:0005089(Rho guanyl-nucleotide exchange factor activity);GO:0035023(regulation of Rho protein signal transduction);GO:0043547(positive regulation of GTPase activity);GO:0005515(protein binding);GO:0016604(nuclear body);GO:0007275(multicellular organism development);GO:0030154(cell differentiation);GO:0005516(calmodulin binding);GO:0051056(regulation of small GTPase mediated signal transduction);GO:0042383(sarcolemma);GO:0031430(M band);GO:0030018(Z disc);GO:0005085(guanyl-nucleotide exchange factor activity);GO:0043065(positive regulation of apoptotic process);GO:0008307(structural constituent of muscle);GO:0031432(titin binding);GO:0045214(sarcomere organization);GO:0030506(ankyrin binding);GO:0030016(myofibril);GO:0036309(protein localization to M-band);GO:0030017(sarcomere)","NA","NA","NA","obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF [Source:HGNC Symbol;Acc:HGNC:15719]",{"v":1.01989,"d":"1.02"},{"v":0.501911,"d":"0.50"},{"v":2.03201364385319,"d":"2.03"},{"v":1.02291008904574,"d":"1.02"},{"v":0.103341410085911,"d":"0.10"},{"v":0.380890067644557,"d":"0.38"},"up","no"]
[94522,"j","chr19","-",2037465,2050910,"MSTRG.7627.1",12,1713,"MSTRG.7627","MKNK2","NA","NA","NA","NA","NA",{"v":11.426429,"d":"11.43"},{"v":5.676096,"d":"5.68"},{"v":2.01307888379619,"d":"2.01"},{"v":1.00940370630385,"d":"1.01"},{"v":0.108453120489893,"d":"0.11"},{"v":0.392033292893226,"d":"0.39"},"up","no"]
[40633,0,"chr12","+",45729665,45908040,"ENST00000334344",21,8642,"ENSG00000189079","ARID2","GO:0008285(negative regulation of cell proliferation);GO:0030336(negative regulation of cell migration);GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0005654(nucleoplasm);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0016569(covalent chromatin modification);GO:0003677(DNA binding);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0006337(nucleosome disassembly);GO:0003007(heart morphogenesis);GO:0042592(homeostatic process);GO:0048568(embryonic organ development);GO:0060038(cardiac muscle cell proliferation);GO:0060982(coronary artery morphogenesis);GO:0072358(cardiovascular system development);GO:0090544(BAF-type complex)","05225(Hepatocellular carcinoma)","K11765","NA","AT-rich interaction domain 2 [Source:HGNC Symbol;Acc:HGNC:18037]",{"v":4.613643,"d":"4.61"},{"v":2.34219,"d":"2.34"},{"v":1.96979877806668,"d":"1.97"},{"v":0.97804826079206,"d":"0.98"},{"v":0.117703972170201,"d":"0.12"},{"v":0.410217209494928,"d":"0.41"},"up","no"]
[158099,0,"chr5","-",131641714,131796921,"ENST00000307968",17,6388,"MSTRG.12281","FNIP1","GO:0005737(cytoplasm);GO:0043547(positive regulation of GTPase activity);GO:0005515(protein binding);GO:0005085(guanyl-nucleotide exchange factor activity);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0001934(positive regulation of protein phosphorylation);GO:0033138(positive regulation of peptidyl-serine phosphorylation);GO:0009267(cellular response to starvation);GO:0032007(negative regulation of TOR signaling);GO:0043154(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process);GO:0051087(chaperone binding);GO:0001932(regulation of protein phosphorylation);GO:0002327(immature B cell differentiation);GO:0031929(TOR signaling);GO:0042030(ATPase inhibitor activity);GO:2000973(regulation of pro-B cell differentiation);GO:0002904(positive regulation of B cell apoptotic process);GO:0031334(positive regulation of protein complex assembly)","04150(mTOR signaling pathway)","K20400","NA","folliculin interacting protein 1 [Source:HGNC Symbol;Acc:HGNC:29418]",{"v":4.165096,"d":"4.17"},{"v":8.799875,"d":"8.80"},{"v":0.47331308683362,"d":"0.47"},{"v":-1.07913328257456,"d":"-1.08"},{"v":0.122436928162555,"d":"0.12"},{"v":0.418848823291057,"d":"0.42"},"down","no"]
[112106,"o","chr2","-",88846693,88866183,"MSTRG.8934.6",4,1303,"MSTRG.8934","AC244205.1","NA","NA","NA","NA","NA",{"v":18.612961,"d":"18.61"},{"v":38.995258,"d":"39.00"},{"v":0.477313446676004,"d":"0.48"},{"v":-1.06699111491977,"d":"-1.07"},{"v":0.127031947204096,"d":"0.13"},{"v":0.427824915124202,"d":"0.43"},"down","no"]
[136101,0,"chr3","+",49020459,49023287,"ENST00000326912",5,705,"MSTRG.10918","NDUFAF3","GO:0005634(nucleus);GO:0016020(membrane);GO:0005743(mitochondrial inner membrane);GO:0005739(mitochondrion);GO:0005515(protein binding);GO:0032981(mitochondrial respiratory chain complex I assembly)","NA","NA","NA","NADH:ubiquinone oxidoreductase complex assembly factor 3 [Source:HGNC Symbol;Acc:HGNC:29918]",{"v":1.462822,"d":"1.46"},{"v":3.176618,"d":"3.18"},{"v":0.460496666580621,"d":"0.46"},{"v":-1.11873738183897,"d":"-1.12"},{"v":0.130719872787784,"d":"0.13"},{"v":0.433334599189026,"d":"0.43"},"down","no"]
[78765,0,"chr17","+",7342935,7344647,"ENST00000571220",5,953,"MSTRG.6393","ACAP1","GO:0006810(transport);GO:0016020(membrane);GO:0015031(protein transport);GO:0043231(intracellular membrane-bounded organelle);GO:0046872(metal ion binding);GO:0043547(positive regulation of GTPase activity);GO:0005515(protein binding);GO:0005096(GTPase activator activity);GO:0005768(endosome);GO:0055038(recycling endosome membrane)","04144(Endocytosis)","NA","NA","ArfGAP with coiled-coil, ankyrin repeat and PH domains 1 [Source:HGNC Symbol;Acc:HGNC:16467]",{"v":19.894646,"d":"19.89"},{"v":10.439691,"d":"10.44"},{"v":1.90567383651489,"d":"1.91"},{"v":0.930301217511865,"d":"0.93"},{"v":0.136573085462066,"d":"0.14"},{"v":0.444948828602797,"d":"0.44"},"up","no"]
[149272,0,"chr4","-",88725955,89057172,"ENST00000264344",24,5858,"MSTRG.11731","FAM13A","GO:0007165(signal transduction);GO:0043547(positive regulation of GTPase activity);GO:0005096(GTPase activator activity);GO:0005829(cytosol);GO:0051056(regulation of small GTPase mediated signal transduction)","NA","NA","NA","family with sequence similarity 13 member A [Source:HGNC Symbol;Acc:HGNC:19367]",{"v":0.942252,"d":"0.94"},{"v":0.491982,"d":"0.49"},{"v":1.91521641035648,"d":"1.92"},{"v":0.937507419047394,"d":"0.94"},{"v":0.14072604648132,"d":"0.14"},{"v":0.451698713412474,"d":"0.45"},"up","no"]
[97553,0,"chr19","-",14408851,14419367,"ENST00000242776",11,1471,"MSTRG.7902","DDX39A","GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0006397(mRNA processing);GO:0008380(RNA splicing);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016607(nuclear speck);GO:0016020(membrane);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0016787(hydrolase activity);GO:0004386(helicase activity);GO:0005515(protein binding);GO:0006406(mRNA export from nucleus);GO:0042802(identical protein binding);GO:0005730(nucleolus);GO:0005654(nucleoplasm);GO:0006974(cellular response to DNA damage stimulus);GO:0004004(ATP-dependent RNA helicase activity);GO:0010501(RNA secondary structure unwinding);GO:0005681(spliceosomal complex);GO:0016887(ATPase activity);GO:0000398(mRNA splicing, via spliceosome);GO:0006369(termination of RNA polymerase II transcription);GO:0006405(RNA export from nucleus);GO:0010468(regulation of gene expression);GO:0031124(mRNA 3'-end processing)","NA","NA","NA","DExD-box helicase 39A [Source:HGNC Symbol;Acc:HGNC:17821]",{"v":10.832108,"d":"10.83"},{"v":5.816669,"d":"5.82"},{"v":1.8622527773198,"d":"1.86"},{"v":0.89704891383882,"d":"0.90"},{"v":0.150306497182247,"d":"0.15"},{"v":0.469396330268238,"d":"0.47"},"up","no"]
[75676,0,"chr16","-",74871367,74985148,"ENST00000262144",26,5898,"ENSG00000103091","WDR59","GO:0016020(membrane);GO:0005765(lysosomal membrane);GO:0005764(lysosome);GO:0005515(protein binding);GO:0003674(molecular_function);GO:0008150(biological_process);GO:0005575(cellular_component);GO:0034198(cellular response to amino acid starvation);GO:0032008(positive regulation of TOR signaling);GO:0061700(GATOR2 complex)","04150(mTOR signaling pathway)","K20409","NA","WD repeat domain 59 [Source:HGNC Symbol;Acc:HGNC:25706]",{"v":2.702048,"d":"2.70"},{"v":1.456029,"d":"1.46"},{"v":1.85576523544517,"d":"1.86"},{"v":0.892014213115576,"d":"0.89"},{"v":0.151602745958962,"d":"0.15"},{"v":0.471527045375163,"d":"0.47"},"up","no"]
[79204,0,"chr17","-",8229358,8232648,"ENST00000578240",7,1653,"MSTRG.6421","CTC1","GO:0005634(nucleus);GO:0003677(DNA binding);GO:0005694(chromosome);GO:0005515(protein binding);GO:0003697(single-stranded DNA binding);GO:0000781(chromosome, telomeric region);GO:0000723(telomere maintenance);GO:0045740(positive regulation of DNA replication);GO:0042162(telomeric DNA binding);GO:0032211(negative regulation of telomere maintenance via telomerase);GO:0000784(nuclear chromosome, telomeric region);GO:0098505(G-rich strand telomeric DNA binding);GO:0016233(telomere capping);GO:0006974(cellular response to DNA damage stimulus);GO:0007568(aging);GO:0010389(regulation of G2/M transition of mitotic cell cycle);GO:0010833(telomere maintenance via telomere lengthening);GO:0035264(multicellular organism growth);GO:0048146(positive regulation of fibroblast proliferation);GO:0048536(spleen development);GO:0048538(thymus development);GO:0048539(bone marrow development);GO:0051276(chromosome organization);GO:0071425(hematopoietic stem cell proliferation);GO:0090399(replicative senescence);GO:1990879(CST complex)","NA","NA","NA","CST telomere replication complex component 1 [Source:HGNC Symbol;Acc:HGNC:26169]",{"v":1.425668,"d":"1.43"},{"v":0.76499,"d":"0.76"},{"v":1.86364266199558,"d":"1.86"},{"v":0.898125261715362,"d":"0.90"},{"v":0.161955351211645,"d":"0.16"},{"v":0.488139540074584,"d":"0.49"},"up","no"]
[199410,0,"chrX","+",111681170,111760645,"ENST00000610588",27,4175,"ENSG00000101901","ALG13","GO:0003723(RNA binding);GO:0016740(transferase activity);GO:0016787(hydrolase activity);GO:0016757(transferase activity, transferring glycosyl groups);GO:0005783(endoplasmic reticulum);GO:0016758(transferase activity, transferring hexosyl groups);GO:0003824(catalytic activity);GO:0008152(metabolic process);GO:0008233(peptidase activity);GO:0008234(cysteine-type peptidase activity);GO:0006508(proteolysis);GO:0036459(thiol-dependent ubiquitinyl hydrolase activity);GO:0005789(endoplasmic reticulum membrane);GO:0006488(dolichol-linked oligosaccharide biosynthetic process);GO:0004577(N-acetylglucosaminyldiphosphodolichol N-acetylglucosaminyltransferase activity);GO:0043541(UDP-N-acetylglucosamine transferase complex)","00510(N-Glycan biosynthesis)","K07432","EC:2.4.1.141","ALG13, UDP-N-acetylglucosaminyltransferase subunit [Source:HGNC Symbol;Acc:HGNC:30881]",{"v":0.841808,"d":"0.84"},{"v":0.458289,"d":"0.46"},{"v":1.83684967345932,"d":"1.84"},{"v":0.877233562089452,"d":"0.88"},{"v":0.16712633979321,"d":"0.17"},{"v":0.49564514376813,"d":"0.50"},"up","no"]
[161505,0,"chr5","-",177301451,177303706,"ENST00000393611",9,1236,"MSTRG.12573","RAB24","GO:0006810(transport);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0015031(protein transport);GO:0005525(GTP binding);GO:0000166(nucleotide binding);GO:0003924(GTPase activity);GO:0005829(cytosol);GO:0006914(autophagy);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0043312(neutrophil degranulation);GO:0030667(secretory granule membrane);GO:0005776(autophagosome);GO:0005739(mitochondrion)","NA","NA","NA","RAB24, member RAS oncogene family [Source:HGNC Symbol;Acc:HGNC:9765]",{"v":6.999414,"d":"7.00"},{"v":3.873286,"d":"3.87"},{"v":1.80709970810315,"d":"1.81"},{"v":0.853676110196646,"d":"0.85"},{"v":0.171476914661395,"d":"0.17"},{"v":0.501662421184939,"d":"0.50"},"up","no"]
[164561,0,"chr6","+",31666087,31668241,"ENST00000465481",3,579,"MSTRG.12871","CSNK2B","GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0045859(regulation of protein kinase activity);GO:0019887(protein kinase regulator activity);GO:0005956(protein kinase CK2 complex);GO:0008285(negative regulation of cell proliferation);GO:0005737(cytoplasm);GO:0043537(negative regulation of blood vessel endothelial cell migration);GO:0061154(endothelial tube morphogenesis);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0005515(protein binding);GO:0007165(signal transduction);GO:0016055(Wnt signaling pathway);GO:0005576(extracellular region);GO:0042802(identical protein binding);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0006457(protein folding);GO:0043312(neutrophil degranulation);GO:0043021(ribonucleoprotein complex binding);GO:0033574(response to testosterone);GO:0097421(liver regeneration);GO:0000785(chromatin);GO:0005886(plasma membrane);GO:0005929(cilium);GO:0016363(nuclear matrix);GO:0042995(cell projection);GO:0019904(protein domain specific binding);GO:0034774(secretory granule lumen);GO:1904813(ficolin-1-rich granule lumen);GO:0031519(PcG protein complex);GO:1901796(regulation of signal transduction by p53 class mediator);GO:0005102(receptor binding);GO:0043623(cellular protein complex assembly);GO:0004674(protein serine/threonine kinase activity);GO:0016236(macroautophagy);GO:0003682(chromatin binding);GO:0008134(transcription factor binding);GO:0010862(positive regulation of pathway-restricted SMAD protein phosphorylation);GO:0006656(phosphatidylcholine biosynthetic process);GO:0032927(positive regulation of activin receptor signaling pathway);GO:0018107(peptidyl-threonine phosphorylation);GO:0033211(adiponectin-activated signaling pathway);GO:0051101(regulation of DNA binding)","03008(Ribosome biogenesis in eukaryotes);04310(Wnt signaling pathway);04064(NF-kappa B signaling pathway);04137(Mitophagy - animal);04520(Adherens junction);05162(Measles);05168(Herpes simplex infection);05169(Epstein-Barr virus infection)","NA","NA","casein kinase 2 beta [Source:HGNC Symbol;Acc:HGNC:2460]",{"v":1.865844,"d":"1.87"},{"v":3.727228,"d":"3.73"},{"v":0.500598299862525,"d":"0.50"},{"v":-0.998274703549629,"d":"-1.00"},{"v":0.176825110987088,"d":"0.18"},{"v":0.510458842878442,"d":"0.51"},"down","no"]
[8777,0,"chr1","+",109250019,109275750,"ENST00000271332",34,10534,"ENSG00000143126","CELSR2","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0004930(G-protein coupled receptor activity);GO:0007186(G-protein coupled receptor signaling pathway);GO:0005509(calcium ion binding);GO:0007155(cell adhesion);GO:0007156(homophilic cell adhesion via plasma membrane adhesion molecules);GO:0005886(plasma membrane);GO:0004871(signal transducer activity);GO:0007165(signal transduction);GO:0004888(transmembrane signaling receptor activity);GO:0007166(cell surface receptor signaling pathway);GO:0007275(multicellular organism development);GO:0048813(dendrite morphogenesis);GO:0060071(Wnt signaling pathway, planar cell polarity pathway);GO:0006355(regulation of transcription, DNA-templated);GO:0016055(Wnt signaling pathway);GO:0022407(regulation of cell-cell adhesion);GO:0021999(neural plate anterior/posterior regionalization)","NA","NA","NA","cadherin EGF LAG seven-pass G-type receptor 2 [Source:HGNC Symbol;Acc:HGNC:3231]",{"v":0.540104,"d":"0.54"},{"v":0.302171,"d":"0.30"},{"v":1.78741176353786,"d":"1.79"},{"v":0.837872024297534,"d":"0.84"},{"v":0.181852611424448,"d":"0.18"},{"v":0.516889381129986,"d":"0.52"},"up","no"]
[124419,0,"chr20","-",47210440,47356697,"ENST00000471951",23,4053,"ENSG00000101040","ZMYND8","GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0005515(protein binding);GO:0003682(chromatin binding);GO:0000977(RNA polymerase II regulatory region sequence-specific DNA binding);GO:0035064(methylated histone binding);GO:0001106(RNA polymerase II transcription corepressor activity);GO:0070577(lysine-acetylated histone binding);GO:0030336(negative regulation of cell migration);GO:0003712(transcription cofactor activity);GO:0070491(repressing transcription factor binding);GO:1903758(negative regulation of transcription from RNA polymerase II promoter by histone modification);GO:0047485(protein N-terminus binding);GO:0051491(positive regulation of filopodium assembly);GO:0060999(positive regulation of dendritic spine development);GO:0098815(modulation of excitatory postsynaptic potential);GO:1902897(regulation of postsynaptic density protein 95 clustering);GO:1902952(positive regulation of dendritic spine maintenance);GO:0005737(cytoplasm);GO:0043197(dendritic spine);GO:0043198(dendritic shaft)","NA","NA","NA","zinc finger MYND-type containing 8 [Source:HGNC Symbol;Acc:HGNC:9397]",{"v":0.682473,"d":"0.68"},{"v":0.380147,"d":"0.38"},{"v":1.79528708631135,"d":"1.80"},{"v":0.844214565429996,"d":"0.84"},{"v":0.186049093358446,"d":"0.19"},{"v":0.521993578218553,"d":"0.52"},"up","no"]
[172990,0,"chr7","+",32495489,32588721,"ENST00000318709",16,6982,"ENSG00000105778","AVL9","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005768(endosome);GO:0055037(recycling endosome);GO:0016477(cell migration)","NA","NA","NA","AVL9 cell migration associated [Source:HGNC Symbol;Acc:HGNC:28994]",{"v":1.85127,"d":"1.85"},{"v":3.499359,"d":"3.50"},{"v":0.529031173995009,"d":"0.53"},{"v":-0.918575356966059,"d":"-0.92"},{"v":0.192548125956972,"d":"0.19"},{"v":0.532122063832141,"d":"0.53"},"down","no"]
[64846,0,"chr15","+",75206444,75209595,"ENST00000565074",1,3152,"MSTRG.5289","C15orf39","GO:0005829(cytosol)","NA","NA","NA","chromosome 15 open reading frame 39 [Source:HGNC Symbol;Acc:HGNC:24497]",{"v":2.781027,"d":"2.78"},{"v":5.236556,"d":"5.24"},{"v":0.531079396458283,"d":"0.53"},{"v":-0.913000534584933,"d":"-0.91"},{"v":0.197629947393523,"d":"0.20"},{"v":0.538818505988637,"d":"0.54"},"down","no"]
[49250,0,"chr13","-",27066142,27171896,"ENST00000282344",9,4511,"MSTRG.3915","USP12","GO:0046872(metal ion binding);GO:0016579(protein deubiquitination);GO:0016787(hydrolase activity);GO:0005515(protein binding);GO:0008233(peptidase activity);GO:0008234(cysteine-type peptidase activity);GO:0006508(proteolysis);GO:0006511(ubiquitin-dependent protein catabolic process);GO:0036459(thiol-dependent ubiquitinyl hydrolase activity);GO:0005575(cellular_component);GO:0005654(nucleoplasm);GO:0004843(thiol-dependent ubiquitin-specific protease activity);GO:0004197(cysteine-type endopeptidase activity);GO:0101005(ubiquitinyl hydrolase activity)","NA","NA","NA","ubiquitin specific peptidase 12 [Source:HGNC Symbol;Acc:HGNC:20485]",{"v":5.742707,"d":"5.74"},{"v":3.366811,"d":"3.37"},{"v":1.70568142969712,"d":"1.71"},{"v":0.770348219508949,"d":"0.77"},{"v":0.210155783583247,"d":"0.21"},{"v":0.557956480067847,"d":"0.56"},"up","no"]
[117090,0,"chr2","-",182909115,183038472,"ENST00000361354",31,20347,"ENSG00000061676","NCKAP1","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005886(plasma membrane);GO:0042995(cell projection);GO:0005515(protein binding);GO:0005925(focal adhesion);GO:0038096(Fc-gamma receptor signaling pathway involved in phagocytosis);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0016032(viral process);GO:0030027(lamellipodium);GO:0030838(positive regulation of actin filament polymerization);GO:0006915(apoptotic process);GO:0007417(central nervous system development);GO:0048010(vascular endothelial growth factor receptor signaling pathway);GO:0032403(protein complex binding);GO:0010592(positive regulation of lamellipodium assembly);GO:0001726(ruffle);GO:0048365(Rac GTPase binding);GO:0031258(lamellipodium membrane);GO:0016601(Rac protein signal transduction);GO:0031209(SCAR complex);GO:0031941(filamentous actin);GO:2000601(positive regulation of Arp2/3 complex-mediated actin nucleation)","04810(Regulation of actin cytoskeleton)","K05750","NA","NCK associated protein 1 [Source:HGNC Symbol;Acc:HGNC:7666]",{"v":0.149476,"d":"0.15"},{"v":0.276734,"d":"0.28"},{"v":0.540143242247068,"d":"0.54"},{"v":-0.888586044138393,"d":"-0.89"},{"v":0.217425660781146,"d":"0.22"},{"v":0.569085803444477,"d":"0.57"},"down","no"]
[120097,0,"chr2","-",231453531,231464594,"ENST00000322723",14,4034,"MSTRG.9489","NCL","GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005730(nucleolus);GO:0003677(DNA binding);GO:0030529(intracellular ribonucleoprotein complex);GO:0005515(protein binding);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0071364(cellular response to epidermal growth factor stimulus);GO:1990830(cellular response to leukemia inhibitory factor);GO:0005654(nucleoplasm);GO:0042802(identical protein binding);GO:0070062(extracellular exosome);GO:0005938(cell cortex);GO:0008022(protein C-terminus binding);GO:0001525(angiogenesis);GO:0036464(cytoplasmic ribonucleoprotein granule);GO:0048027(mRNA 5'-UTR binding);GO:0017148(negative regulation of translation);GO:0042162(telomeric DNA binding);GO:0044547(DNA topoisomerase binding);GO:1901838(positive regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter)","05130(Pathogenic Escherichia coli infection)","K11294","NA","nucleolin [Source:HGNC Symbol;Acc:HGNC:7667]",{"v":67.684975,"d":"67.68"},{"v":40.39473,"d":"40.39"},{"v":1.67558924146788,"d":"1.68"},{"v":0.744668526169092,"d":"0.74"},{"v":0.222549990852962,"d":"0.22"},{"v":0.575557339379866,"d":"0.58"},"up","no"]
[110907,0,"chr2","+",71068978,71078636,"ENST00000489309",6,4388,"MSTRG.8814","NAGK","GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0005515(protein binding);GO:0046835(carbohydrate phosphorylation);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0006048(UDP-N-acetylglucosamine biosynthetic process);GO:0006044(N-acetylglucosamine metabolic process);GO:0019262(N-acetylneuraminate catabolic process);GO:0045127(N-acetylglucosamine kinase activity);GO:0006051(N-acetylmannosamine metabolic process)","00520(Amino sugar and nucleotide sugar metabolism)","NA","NA","N-acetylglucosamine kinase [Source:HGNC Symbol;Acc:HGNC:17174]",{"v":0.221465,"d":"0.22"},{"v":0.410865,"d":"0.41"},{"v":0.539021333041267,"d":"0.54"},{"v":-0.891585722718864,"d":"-0.89"},{"v":0.227832545424553,"d":"0.23"},{"v":0.582141699753702,"d":"0.58"},"down","no"]
[36864,0,"chr11","+",128693770,128813267,"ENST00000527786",9,4127,"MSTRG.2969","FLI1","GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0006355(regulation of transcription, DNA-templated);GO:0005634(nucleus);GO:0043565(sequence-specific DNA binding);GO:0005829(cytosol);GO:0006366(transcription from RNA polymerase II promoter);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0016604(nuclear body);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:0000980(RNA polymerase II distal enhancer sequence-specific DNA binding);GO:0001077(transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0003682(chromatin binding);GO:0008015(blood circulation);GO:0009887(animal organ morphogenesis);GO:0035855(megakaryocyte development);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0045893(positive regulation of transcription, DNA-templated);GO:0000981(RNA polymerase II transcription factor activity, sequence-specific DNA binding);GO:0030154(cell differentiation);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0007599(hemostasis)","05202(Transcriptional misregulation in cancers)","K09436","NA","Fli-1 proto-oncogene, ETS transcription factor [Source:HGNC Symbol;Acc:HGNC:3749]",{"v":15.396995,"d":"15.40"},{"v":27.616871,"d":"27.62"},{"v":0.557521342660434,"d":"0.56"},{"v":-0.842901060507334,"d":"-0.84"},{"v":0.232573647206397,"d":"0.23"},{"v":0.586293471457812,"d":"0.59"},"down","no"]
[74256,0,"chr16","+",67029147,67101058,"ENST00000290858",6,3136,"MSTRG.6003","CBFB","GO:0005634(nucleus);GO:0003713(transcription coactivator activity);GO:1903506(regulation of nucleic acid-templated transcription);GO:0016020(membrane);GO:0005515(protein binding);GO:0005654(nucleoplasm);GO:1902036(regulation of hematopoietic stem cell differentiation);GO:0006366(transcription from RNA polymerase II promoter);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:2000810(regulation of bicellular tight junction assembly);GO:0045652(regulation of megakaryocyte differentiation);GO:0030111(regulation of Wnt signaling pathway);GO:0033146(regulation of intracellular estrogen receptor signaling pathway);GO:0045616(regulation of keratinocyte differentiation);GO:0045589(regulation of regulatory T cell differentiation);GO:0045637(regulation of myeloid cell differentiation);GO:0001959(regulation of cytokine-mediated signaling pathway);GO:0050855(regulation of B cell receptor signaling pathway);GO:0000209(protein polyubiquitination);GO:0003677(DNA binding);GO:0001503(ossification);GO:0001649(osteoblast differentiation);GO:0030098(lymphocyte differentiation);GO:0030099(myeloid cell differentiation);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0048469(cell maturation);GO:0060216(definitive hemopoiesis)","NA","NA","NA","core-binding factor beta subunit [Source:HGNC Symbol;Acc:HGNC:1539]",{"v":4.625094,"d":"4.63"},{"v":2.797379,"d":"2.80"},{"v":1.65336695528207,"d":"1.65"},{"v":0.725406958031421,"d":"0.73"},{"v":0.237949014718675,"d":"0.24"},{"v":0.592957185311682,"d":"0.59"},"up","no"]
[156292,0,"chr5","+",81301603,81313297,"ENST00000254037",5,4606,"ENSG00000131732","ZCCHC9","GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0005634(nucleus);GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0006351(transcription, DNA-templated);GO:0005730(nucleolus);GO:0010923(negative regulation of phosphatase activity)","NA","NA","NA","zinc finger CCHC-type containing 9 [Source:HGNC Symbol;Acc:HGNC:25424]",{"v":0.368343,"d":"0.37"},{"v":0.219517,"d":"0.22"},{"v":1.67797027109518,"d":"1.68"},{"v":0.746717155513434,"d":"0.75"},{"v":0.245014319390666,"d":"0.25"},{"v":0.602443779041105,"d":"0.60"},"up","no"]
[124339,0,"chr20","-",46366049,46406617,"ENST00000290246",22,3669,"MSTRG.9797","ELMO2","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005829(cytosol);GO:0006915(apoptotic process);GO:0016477(cell migration);GO:0038096(Fc-gamma receptor signaling pathway involved in phagocytosis);GO:0007010(cytoskeleton organization);GO:0005515(protein binding);GO:0017124(SH3 domain binding);GO:0098609(cell-cell adhesion);GO:0006909(phagocytosis);GO:0030971(receptor tyrosine kinase binding);GO:0048010(vascular endothelial growth factor receptor signaling pathway);GO:0060326(cell chemotaxis);GO:0016021(integral component of membrane)","05131(Shigellosis);05100(Bacterial invasion of epithelial cells)","K18985","NA","engulfment and cell motility 2 [Source:HGNC Symbol;Acc:HGNC:17233]",{"v":8.67147,"d":"8.67"},{"v":5.386741,"d":"5.39"},{"v":1.60978038483751,"d":"1.61"},{"v":0.686863881310562,"d":"0.69"},{"v":0.258713707581919,"d":"0.26"},{"v":0.62043936192696,"d":"0.62"},"up","no"]
[17100,0,"chr1","+",234373468,234384048,"ENST00000619305",3,697,"ENSG00000168275","COA6","GO:0003723(RNA binding);GO:0005739(mitochondrion);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0005758(mitochondrial intermembrane space);GO:0005507(copper ion binding);GO:0008535(respiratory chain complex IV assembly);GO:0042774(plasma membrane ATP synthesis coupled electron transport)","NA","NA","NA","cytochrome c oxidase assembly factor 6 [Source:HGNC Symbol;Acc:HGNC:18025]",{"v":1.632906,"d":"1.63"},{"v":0.98005,"d":"0.98"},{"v":1.66614560481608,"d":"1.67"},{"v":0.736514483636883,"d":"0.74"},{"v":0.263939551198521,"d":"0.26"},{"v":0.625921668984041,"d":"0.63"},"up","no"]
[5721,0,"chr1","-",46632737,46668454,"ENST00000576409",9,4158,"ENSG00000123472","ATPAF1","GO:0005739(mitochondrion);GO:0006461(protein complex assembly);GO:0005515(protein binding);GO:0033615(mitochondrial proton-transporting ATP synthase complex assembly)","NA","NA","NA","ATP synthase mitochondrial F1 complex assembly factor 1 [Source:HGNC Symbol;Acc:HGNC:18803]",{"v":0.627073,"d":"0.63"},{"v":1.095391,"d":"1.10"},{"v":0.572464991952645,"d":"0.57"},{"v":-0.804740624351279,"d":"-0.80"},{"v":0.267554679344061,"d":"0.27"},{"v":0.630147293237653,"d":"0.63"},"down","no"]
[23143,0,"chr10","+",102644496,102658407,"ENST00000302424",6,2831,"MSTRG.1937","TRIM8","GO:0046872(metal ion binding);GO:0016740(transferase activity);GO:0016567(protein ubiquitination);GO:0008270(zinc ion binding);GO:0042803(protein homodimerization activity);GO:0005515(protein binding);GO:0045087(innate immune response);GO:0042802(identical protein binding);GO:0005829(cytosol);GO:0010508(positive regulation of autophagy);GO:0043123(positive regulation of I-kappaB kinase/NF-kappaB signaling);GO:0051092(positive regulation of NF-kappaB transcription factor activity);GO:0016605(PML body);GO:0051091(positive regulation of sequence-specific DNA binding transcription factor activity);GO:0060333(interferon-gamma-mediated signaling pathway);GO:1902187(negative regulation of viral release from host cell);GO:0019827(stem cell population maintenance);GO:0032897(negative regulation of viral transcription);GO:0046597(negative regulation of viral entry into host cell);GO:1900182(positive regulation of protein localization to nucleus);GO:0005634(nucleus)","NA","NA","NA","tripartite motif containing 8 [Source:HGNC Symbol;Acc:HGNC:15579]",{"v":16.964365,"d":"16.96"},{"v":28.984451,"d":"28.98"},{"v":0.585291920830241,"d":"0.59"},{"v":-0.77277173055139,"d":"-0.77"},{"v":0.276726322687083,"d":"0.28"},{"v":0.641230019434726,"d":"0.64"},"down","no"]
[93209,0,"chr18","+",63907991,63936111,"ENST00000238508",8,2122,"ENSG00000242550","SERPINB10","GO:0005615(extracellular space);GO:0043066(negative regulation of apoptotic process);GO:0004867(serine-type endopeptidase inhibitor activity);GO:0010951(negative regulation of endopeptidase activity);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0030414(peptidase inhibitor activity);GO:0010466(negative regulation of peptidase activity);GO:0043312(neutrophil degranulation);GO:0030667(secretory granule membrane);GO:0101003(ficolin-1-rich granule membrane)","05146(Amoebiasis)","K13963","NA","serpin family B member 10 [Source:HGNC Symbol;Acc:HGNC:8942]",{"v":0.727832,"d":"0.73"},{"v":1.266393,"d":"1.27"},{"v":0.574728382105713,"d":"0.57"},{"v":-0.799047798607552,"d":"-0.80"},{"v":0.282740309799523,"d":"0.28"},{"v":0.648267138141793,"d":"0.65"},"down","no"]
[18850,0,"chr10","+",17229278,17237593,"ENST00000224237",9,1868,"MSTRG.1597","VIM","GO:0005737(cytoplasm);GO:0005198(structural molecule activity);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0005882(intermediate filament);GO:0005925(focal adhesion);GO:0005777(peroxisome);GO:0042802(identical protein binding);GO:0005200(structural constituent of cytoskeleton);GO:0070062(extracellular exosome);GO:0016032(viral process);GO:0031012(extracellular matrix);GO:0008022(protein C-terminus binding);GO:0097110(scaffold protein binding);GO:0006928(movement of cell or subcellular component);GO:0030049(muscle filament sliding);GO:0003725(double-stranded RNA binding);GO:0005212(structural constituent of eye lens);GO:1990254(keratin filament binding);GO:0010628(positive regulation of gene expression);GO:0010977(negative regulation of neuron projection development);GO:0014002(astrocyte development);GO:0045103(intermediate filament-based process);GO:0045109(intermediate filament organization);GO:0060020(Bergmann glial cell differentiation);GO:0060395(SMAD protein signal transduction);GO:0070307(lens fiber cell development);GO:0031252(cell leading edge);GO:0042995(cell projection);GO:0043005(neuron projection)","05206(MicroRNAs in cancer);05169(Epstein-Barr virus infection)","K07606","NA","vimentin [Source:HGNC Symbol;Acc:HGNC:12692]",{"v":187.622543,"d":"187.62"},{"v":120.702461,"d":"120.70"},{"v":1.55442185226033,"d":"1.55"},{"v":0.636378087769044,"d":"0.64"},{"v":0.290561083885625,"d":"0.29"},{"v":0.657946172957985,"d":"0.66"},"up","no"]
[31364,0,"chr11","+",65711996,65719604,"ENST00000377046",14,2237,"MSTRG.2558","KAT5","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0005654(nucleoplasm);GO:0016740(transferase activity);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0016569(covalent chromatin modification);GO:0016746(transferase activity, transferring acyl groups);GO:0005515(protein binding);GO:0016747(transferase activity, transferring acyl groups other than amino-acyl groups);GO:0048471(perinuclear region of cytoplasm);GO:0004402(histone acetyltransferase activity);GO:0016573(histone acetylation);GO:0003713(transcription coactivator activity);GO:0045893(positive regulation of transcription, DNA-templated);GO:0005730(nucleolus);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0040008(regulation of growth);GO:0016032(viral process);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:1904837(beta-catenin-TCF complex assembly);GO:1901796(regulation of signal transduction by p53 class mediator);GO:0043161(proteasome-mediated ubiquitin-dependent protein catabolic process);GO:0045892(negative regulation of transcription, DNA-templated);GO:0006260(DNA replication);GO:0030521(androgen receptor signaling pathway);GO:0000731(DNA synthesis involved in DNA repair);GO:0000732(strand displacement);GO:0050681(androgen receptor binding);GO:0071392(cellular response to estradiol stimulus);GO:0000729(DNA double-strand break processing);GO:0006302(double-strand break repair);GO:0006303(double-strand break repair via nonhomologous end joining);GO:0010212(response to ionizing radiation);GO:1901985(positive regulation of protein acetylation);GO:0035267(NuA4 histone acetyltransferase complex);GO:0032703(negative regulation of interleukin-2 production);GO:0070491(repressing transcription factor binding);GO:0006978(DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator);GO:0016407(acetyltransferase activity);GO:0000812(Swr1 complex);GO:0032777(Piccolo NuA4 histone acetyltransferase complex);GO:0005667(transcription factor complex)","05166(HTLV-I infection)","K11304","EC:2.3.1.48","lysine acetyltransferase 5 [Source:HGNC Symbol;Acc:HGNC:5275]",{"v":1.640589,"d":"1.64"},{"v":2.777688,"d":"2.78"},{"v":0.590631129198096,"d":"0.59"},{"v":-0.759670699207554,"d":"-0.76"},{"v":0.296044942383548,"d":"0.30"},{"v":0.663534112640553,"d":"0.66"},"down","no"]
[14835,0,"chr1","+",201955491,201970661,"ENST00000367287",6,1659,"MSTRG.1292","TIMM17A","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0006886(intracellular protein transport);GO:0015031(protein transport);GO:0005654(nucleoplasm);GO:0015450(P-P-bond-hydrolysis-driven protein transmembrane transporter activity);GO:0005739(mitochondrion);GO:0005743(mitochondrial inner membrane);GO:0005744(mitochondrial inner membrane presequence translocase complex);GO:0015266(protein channel activity);GO:0006626(protein targeting to mitochondrion);GO:0030150(protein import into mitochondrial matrix);GO:0031305(integral component of mitochondrial inner membrane)","NA","NA","NA","translocase of inner mitochondrial membrane 17A [Source:HGNC Symbol;Acc:HGNC:17315]",{"v":5.284494,"d":"5.28"},{"v":3.423119,"d":"3.42"},{"v":1.54376578786773,"d":"1.54"},{"v":0.626453891004692,"d":"0.63"},{"v":0.303253254302159,"d":"0.30"},{"v":0.671443906920174,"d":"0.67"},"up","no"]
[2890,0,"chr1","-",25304796,25337401,"ENST00000567741",3,597,"MSTRG.260","RSRP1","GO:0005515(protein binding)","NA","NA","NA","arginine and serine rich protein 1 [Source:HGNC Symbol;Acc:HGNC:25234]",{"v":3.219557,"d":"3.22"},{"v":5.372918,"d":"5.37"},{"v":0.599219455796645,"d":"0.60"},{"v":-0.738843628090606,"d":"-0.74"},{"v":0.317252536597307,"d":"0.32"},{"v":0.686933273777383,"d":"0.69"},"down","no"]
[161620,"j","chr5","-",177503612,177509856,"MSTRG.12582.6",6,1910,"MSTRG.12582","DOK3","NA","NA","NA","NA","NA",{"v":3.000122,"d":"3.00"},{"v":4.916461,"d":"4.92"},{"v":0.610219830890553,"d":"0.61"},{"v":-0.712599029584739,"d":"-0.71"},{"v":0.323197442595709,"d":"0.32"},{"v":0.692893121510749,"d":"0.69"},"down","no"]
[90261,"j","chr18","-",2916999,2982873,"MSTRG.7384.4",20,6200,"MSTRG.7384","LPIN2","NA","NA","NA","NA","NA",{"v":1.848507,"d":"1.85"},{"v":1.230184,"d":"1.23"},{"v":1.50262643637049,"d":"1.50"},{"v":0.587486389572206,"d":"0.59"},{"v":0.33044427992112,"d":"0.33"},{"v":0.700308998245058,"d":"0.70"},"up","no"]
[10117,0,"chr1","-",145993579,145994216,"ENST00000486597",2,509,"MSTRG.859","TXNIP","GO:0005737(cytoplasm);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0005515(protein binding);GO:0043086(negative regulation of catalytic activity);GO:0007049(cell cycle);GO:0004857(enzyme inhibitor activity);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0006606(protein import into nucleus);GO:0006979(response to oxidative stress);GO:0009612(response to mechanical stimulus);GO:0009749(response to glucose);GO:0032355(response to estradiol);GO:0032570(response to progesterone);GO:0042127(regulation of cell proliferation);GO:0042493(response to drug);GO:0042542(response to hydrogen peroxide);GO:0043065(positive regulation of apoptotic process);GO:0048008(platelet-derived growth factor receptor signaling pathway);GO:0051592(response to calcium ion);GO:0005634(nucleus);GO:0005758(mitochondrial intermembrane space);GO:0005829(cytosol);GO:0031625(ubiquitin protein ligase binding);GO:0030216(keratinocyte differentiation);GO:0051782(negative regulation of cell division);GO:0071228(cellular response to tumor cell)","04621(NOD-like receptor signaling pathway)","NA","NA","thioredoxin interacting protein [Source:HGNC Symbol;Acc:HGNC:16952]",{"v":3.669345,"d":"3.67"},{"v":6.04983,"d":"6.05"},{"v":0.606520348505661,"d":"0.61"},{"v":-0.7213720469105,"d":"-0.72"},{"v":0.334572318532336,"d":"0.33"},{"v":0.704152716469829,"d":"0.70"},"down","no"]
[86291,0,"chr17","+",59707648,59773804,"ENST00000593168",5,558,"MSTRG.7072","VMP1","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005783(endoplasmic reticulum);GO:0005730(nucleolus);GO:0007155(cell adhesion);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0006914(autophagy);GO:0000421(autophagosome membrane);GO:0000407(pre-autophagosomal structure);GO:0007030(Golgi organization);GO:0005773(vacuole);GO:0005774(vacuolar membrane);GO:0006887(exocytosis);GO:0016337(single organismal cell-cell adhesion);GO:0033116(endoplasmic reticulum-Golgi intermediate compartment membrane);GO:0034329(cell junction assembly);GO:0007029(endoplasmic reticulum organization);GO:0007566(embryo implantation)","04140(Autophagy - animal)","NA","NA","vacuole membrane protein 1 [Source:HGNC Symbol;Acc:HGNC:29559]",{"v":1.701093,"d":"1.70"},{"v":2.780243,"d":"2.78"},{"v":0.6118504749405,"d":"0.61"},{"v":-0.70874896716319,"d":"-0.71"},{"v":0.343084265263853,"d":"0.34"},{"v":0.711602482008892,"d":"0.71"},"down","no"]
[115675,0,"chr2","-",160272151,160493794,"ENST00000348849",14,4273,"MSTRG.9181","RBMS1","GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0005634(nucleus);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0006260(DNA replication);GO:0003690(double-stranded DNA binding);GO:0003697(single-stranded DNA binding);GO:0006396(RNA processing)","NA","NA","NA","RNA binding motif single stranded interacting protein 1 [Source:HGNC Symbol;Acc:HGNC:9907]",{"v":5.255272,"d":"5.26"},{"v":3.564167,"d":"3.56"},{"v":1.47447411975926,"d":"1.47"},{"v":0.560200500173372,"d":"0.56"},{"v":0.34876374043221,"d":"0.35"},{"v":0.716989021821308,"d":"0.72"},"up","no"]
[195713,0,"chrX","+",12975658,12977081,"ENST00000380633",3,495,"MSTRG.15172","TMSB4X","GO:0003723(RNA binding);GO:0005737(cytoplasm);GO:0007015(actin filament organization);GO:0003779(actin binding);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0003785(actin monomer binding);GO:0002576(platelet degranulation);GO:0005829(cytosol);GO:0031093(platelet alpha granule lumen);GO:0005634(nucleus);GO:0019899(enzyme binding);GO:0005622(intracellular);GO:0043536(positive regulation of blood vessel endothelial cell migration);GO:2001171(positive regulation of ATP biosynthetic process);GO:0033209(tumor necrosis factor-mediated signaling pathway);GO:0007253(cytoplasmic sequestering of NF-kappaB);GO:0032088(negative regulation of NF-kappaB transcription factor activity);GO:0042989(sequestering of actin monomers);GO:0050727(regulation of inflammatory response);GO:1901222(regulation of NIK/NF-kappaB signaling);GO:1901223(negative regulation of NIK/NF-kappaB signaling);GO:1903026(negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding);GO:1905273(positive regulation of proton-transporting ATP synthase activity, rotational mechanism);GO:2000483(negative regulation of interleukin-8 secretion);GO:2001028(positive regulation of endothelial cell chemotaxis);GO:0001649(osteoblast differentiation)","04810(Regulation of actin cytoskeleton)","NA","NA","thymosin beta 4, X-linked [Source:HGNC Symbol;Acc:HGNC:11881]",{"v":1.245979,"d":"1.25"},{"v":2.066028,"d":"2.07"},{"v":0.603079435515879,"d":"0.60"},{"v":-0.729580053496561,"d":"-0.73"},{"v":0.354411407474478,"d":"0.35"},{"v":0.721720974855329,"d":"0.72"},"down","no"]
[61587,0,"chr15","+",42495306,42533059,"ENST00000349777",7,2480,"MSTRG.5013","SNAP23","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0006810(transport);GO:0005737(cytoplasm);GO:0015031(protein transport);GO:0005654(nucleoplasm);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0030054(cell junction);GO:0045202(synapse);GO:0098793(presynapse);GO:0005925(focal adhesion);GO:0042629(mast cell granule);GO:0070062(extracellular exosome);GO:0002479(antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent);GO:0043312(neutrophil degranulation);GO:0035579(specific granule membrane);GO:0070821(tertiary granule membrane);GO:0005484(SNAP receptor activity);GO:0005913(cell-cell adherens junction);GO:0019905(syntaxin binding);GO:0002553(histamine secretion by mast cell);GO:0006892(post-Golgi vesicle-mediated transport);GO:0006903(vesicle targeting);GO:0016082(synaptic vesicle priming);GO:0031629(synaptic vesicle fusion to presynaptic active zone membrane);GO:0061025(membrane fusion);GO:0030670(phagocytic vesicle membrane);GO:0031201(SNARE complex);GO:0042581(specific granule);GO:0042582(azurophil granule);GO:0043005(neuron projection)","04130(SNARE interactions in vesicular transport);04611(Platelet activation)","K08508","NA","synaptosome associated protein 23 [Source:HGNC Symbol;Acc:HGNC:11131]",{"v":2.312845,"d":"2.31"},{"v":3.639134,"d":"3.64"},{"v":0.635548182617073,"d":"0.64"},{"v":-0.653926590919654,"d":"-0.65"},{"v":0.370178810076545,"d":"0.37"},{"v":0.737256181887936,"d":"0.74"},"down","no"]
[23265,0,"chr10","-",103882555,103917669,"ENST00000369764",9,1311,"MSTRG.1955","STN1","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0043231(intracellular membrane-bounded organelle);GO:0005654(nucleoplasm);GO:0003677(DNA binding);GO:0001650(fibrillar center);GO:0005694(chromosome);GO:0045111(intermediate filament cytoskeleton);GO:0005515(protein binding);GO:0043047(single-stranded telomeric DNA binding);GO:0000781(chromosome, telomeric region);GO:0016233(telomere capping);GO:0000784(nuclear chromosome, telomeric region);GO:0000723(telomere maintenance);GO:1990879(CST complex);GO:0045740(positive regulation of DNA replication);GO:0003697(single-stranded DNA binding);GO:0042162(telomeric DNA binding);GO:0032211(negative regulation of telomere maintenance via telomerase);GO:0010833(telomere maintenance via telomere lengthening)","NA","NA","NA","STN1, CST complex subunit [Source:HGNC Symbol;Acc:HGNC:26200]",{"v":3.412333,"d":"3.41"},{"v":2.357533,"d":"2.36"},{"v":1.44741685482239,"d":"1.45"},{"v":0.533480476656221,"d":"0.53"},{"v":0.374424053277295,"d":"0.37"},{"v":0.738930568871421,"d":"0.74"},"up","no"]
[155344,0,"chr5","+",66163583,66180879,"ENST00000519259",5,9353,"ENSG00000153914","SREK1","GO:0016607(nuclear speck);GO:0005654(nucleoplasm);GO:0000381(regulation of alternative mRNA splicing, via spliceosome);GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0006397(mRNA processing);GO:0008380(RNA splicing);GO:0005634(nucleus);GO:0005515(protein binding);GO:0005681(spliceosomal complex)","NA","NA","NA","splicing regulatory glutamic acid and lysine rich protein 1 [Source:HGNC Symbol;Acc:HGNC:17882]",{"v":0.30152,"d":"0.30"},{"v":0.472954,"d":"0.47"},{"v":0.637525002431526,"d":"0.64"},{"v":-0.649446172246611,"d":"-0.65"},{"v":0.381038692402705,"d":"0.38"},{"v":0.745042820030421,"d":"0.75"},"down","no"]
[31500,0,"chr11","+",65961689,65979828,"ENST00000312397",20,3293,"MSTRG.2568","SART1","GO:0003723(RNA binding);GO:0006397(mRNA processing);GO:0008380(RNA splicing);GO:0005634(nucleus);GO:0016607(nuclear speck);GO:0005794(Golgi apparatus);GO:0005829(cytosol);GO:0005515(protein binding);GO:0005681(spliceosomal complex);GO:0000398(mRNA splicing, via spliceosome);GO:0005654(nucleoplasm);GO:0007050(cell cycle arrest);GO:0046540(U4/U6 x U5 tri-snRNP complex);GO:0005737(cytoplasm);GO:0097193(intrinsic apoptotic signaling pathway);GO:0045292(mRNA cis splicing, via spliceosome);GO:0015030(Cajal body);GO:0000387(spliceosomal snRNP assembly);GO:0000481(maturation of 5S rRNA);GO:0045585(positive regulation of cytotoxic T cell differentiation);GO:0071013(catalytic step 2 spliceosome)","03040(Spliceosome)","K11984","NA","SART1, U4/U6.U5 tri-snRNP-associated protein 1 [Source:HGNC Symbol;Acc:HGNC:10538]",{"v":18.762833,"d":"18.76"},{"v":13.190607,"d":"13.19"},{"v":1.42243893704058,"d":"1.42"},{"v":0.50836672134057,"d":"0.51"},{"v":0.38869521150283,"d":"0.39"},{"v":0.752224886917661,"d":"0.75"},"up","no"]
[58353,0,"chr14","-",99169287,99271228,"ENST00000357195",4,7559,"MSTRG.4653","BCL11B","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006366(transcription from RNA polymerase II promoter);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0005515(protein binding);GO:0007165(signal transduction);GO:0001077(transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:0043565(sequence-specific DNA binding);GO:0003334(keratinocyte development);GO:0003382(epithelial cell morphogenesis);GO:0007409(axonogenesis);GO:0008285(negative regulation of cell proliferation);GO:0009791(post-embryonic development);GO:0010468(regulation of gene expression);GO:0010837(regulation of keratinocyte proliferation);GO:0019216(regulation of lipid metabolic process);GO:0021773(striatal medium spiny neuron differentiation);GO:0021902(commitment of neuronal cell to specific neuron type in forebrain);GO:0021953(central nervous system neuron differentiation);GO:0031077(post-embryonic camera-type eye development);GO:0033077(T cell differentiation in thymus);GO:0033153(T cell receptor V(D)J recombination);GO:0042475(odontogenesis of dentin-containing tooth);GO:0043066(negative regulation of apoptotic process);GO:0043368(positive T cell selection);GO:0043588(skin development);GO:0045664(regulation of neuron differentiation);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0046632(alpha-beta T cell differentiation);GO:0048538(thymus development);GO:0071678(olfactory bulb axon guidance);GO:0005622(intracellular);GO:0043005(neuron projection);GO:0044212(transcription regulatory region DNA binding);GO:0022008(neurogenesis);GO:0035701(hematopoietic stem cell migration);GO:0097535(lymphoid lineage cell migration into thymus)","05202(Transcriptional misregulation in cancers)","K22046","NA","B-cell CLL/lymphoma 11B [Source:HGNC Symbol;Acc:HGNC:13222]",{"v":1.283779,"d":"1.28"},{"v":1.975673,"d":"1.98"},{"v":0.649793260321926,"d":"0.65"},{"v":-0.621947314825014,"d":"-0.62"},{"v":0.393829829467509,"d":"0.39"},{"v":0.75542690055785,"d":"0.76"},"down","no"]
[199649,0,"chrX","-",119786506,119791643,"ENST00000361575",3,401,"MSTRG.15420","RPL39","GO:0003723(RNA binding);GO:0006412(translation);GO:0030529(intracellular ribonucleoprotein complex);GO:0005622(intracellular);GO:0003735(structural constituent of ribosome);GO:0005840(ribosome);GO:0005615(extracellular space);GO:0005829(cytosol);GO:0002227(innate immune response in mucosa);GO:0019731(antibacterial humoral response);GO:0050830(defense response to Gram-positive bacterium);GO:0061844(antimicrobial humoral immune response mediated by antimicrobial peptide);GO:0006413(translational initiation);GO:0006364(rRNA processing);GO:0000184(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay);GO:0019083(viral transcription);GO:0006614(SRP-dependent cotranslational protein targeting to membrane);GO:0022625(cytosolic large ribosomal subunit)","03010(Ribosome)","K02924","NA","ribosomal protein L39 [Source:HGNC Symbol;Acc:HGNC:10350]",{"v":85.405136,"d":"85.41"},{"v":130.311386,"d":"130.31"},{"v":0.655392737515661,"d":"0.66"},{"v":-0.609568408592273,"d":"-0.61"},{"v":0.400845603545675,"d":"0.40"},{"v":0.760204962899778,"d":"0.76"},"down","no"]
[85919,0,"chr17","+",56978105,57006763,"ENST00000262288",13,1942,"MSTRG.7043","SCPEP1","GO:0016787(hydrolase activity);GO:0005829(cytosol);GO:0008233(peptidase activity);GO:0006508(proteolysis);GO:0005576(extracellular region);GO:0004180(carboxypeptidase activity);GO:0004185(serine-type carboxypeptidase activity);GO:0070062(extracellular exosome);GO:0045776(negative regulation of blood pressure);GO:0042573(retinoic acid metabolic process);GO:0051603(proteolysis involved in cellular protein catabolic process);GO:0097755(positive regulation of blood vessel diameter)","NA","NA","NA","serine carboxypeptidase 1 [Source:HGNC Symbol;Acc:HGNC:29507]",{"v":10.418091,"d":"10.42"},{"v":7.414486,"d":"7.41"},{"v":1.40509955781156,"d":"1.41"},{"v":0.490672355693474,"d":"0.49"},{"v":0.405428549399844,"d":"0.41"},{"v":0.763087687285897,"d":"0.76"},"up","no"]
[134479,0,"chr3","-",33090421,33096801,"ENST00000416695",2,3451,"MSTRG.10787","TMPPE","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0046872(metal ion binding);GO:0016787(hydrolase activity)","NA","NA","NA","transmembrane protein with metallophosphoesterase domain [Source:HGNC Symbol;Acc:HGNC:33865]",{"v":0.439456,"d":"0.44"},{"v":0.307709,"d":"0.31"},{"v":1.42815452261715,"d":"1.43"},{"v":0.514152083675737,"d":"0.51"},{"v":0.418644228600578,"d":"0.42"},{"v":0.772613443980821,"d":"0.77"},"up","no"]
[11249,0,"chr1","-",153939588,153940652,"ENST00000485359",2,891,"MSTRG.994","DENND4B","GO:0005794(Golgi apparatus);GO:0005634(nucleus);GO:0043547(positive regulation of GTPase activity);GO:0005085(guanyl-nucleotide exchange factor activity);GO:0005829(cytosol);GO:0017112(Rab guanyl-nucleotide exchange factor activity);GO:0061024(membrane organization);GO:0032483(regulation of Rab protein signal transduction)","NA","NA","NA","DENN domain containing 4B [Source:HGNC Symbol;Acc:HGNC:29044]",{"v":1.227582,"d":"1.23"},{"v":1.883008,"d":"1.88"},{"v":0.651926067228604,"d":"0.65"},{"v":-0.617219732410365,"d":"-0.62"},{"v":0.424585263617878,"d":"0.42"},{"v":0.776173036281902,"d":"0.78"},"down","no"]
[35693,0,"chr11","+",118304737,118316175,"ENST00000526146",7,2643,"MSTRG.2880","CD3E","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0004888(transmembrane signaling receptor activity);GO:0007166(cell surface receptor signaling pathway);GO:0002376(immune system process);GO:0050776(regulation of immune response);GO:0005887(integral component of plasma membrane);GO:0019901(protein kinase binding);GO:0010628(positive regulation of gene expression);GO:0050852(T cell receptor signaling pathway);GO:0042102(positive regulation of T cell proliferation);GO:0017124(SH3 domain binding);GO:0042981(regulation of apoptotic process);GO:0007186(G-protein coupled receptor signaling pathway);GO:0010629(negative regulation of gene expression);GO:0046982(protein heterodimerization activity);GO:0042110(T cell activation);GO:0007169(transmembrane receptor protein tyrosine kinase signaling pathway);GO:0006461(protein complex assembly);GO:0005057(signal transducer activity, downstream of receptor);GO:0031295(T cell costimulation);GO:0042803(protein homodimerization activity);GO:0051260(protein homooligomerization);GO:0030159(receptor signaling complex scaffold activity);GO:0009897(external side of plasma membrane);GO:0042101(T cell receptor complex);GO:0042608(T cell receptor binding);GO:0004871(signal transducer activity);GO:0002669(positive regulation of T cell anergy);GO:0007172(signal complex assembly);GO:0007584(response to nutrient);GO:0016358(dendrite development);GO:0021549(cerebellum development);GO:0032729(positive regulation of interferon-gamma production);GO:0032753(positive regulation of interleukin-4 production);GO:0033077(T cell differentiation in thymus);GO:0045060(negative thymic T cell selection);GO:0045086(positive regulation of interleukin-2 biosynthetic process);GO:0045879(negative regulation of smoothened signaling pathway);GO:0046641(positive regulation of alpha-beta T cell proliferation);GO:0046649(lymphocyte activation);GO:0050731(positive regulation of peptidyl-tyrosine phosphorylation);GO:0050850(positive regulation of calcium-mediated signaling);GO:0050870(positive regulation of T cell activation);GO:0097190(apoptotic signaling pathway);GO:0001772(immunological synapse);GO:0005911(cell-cell junction);GO:0042105(alpha-beta T cell receptor complex);GO:0043197(dendritic spine);GO:0044297(cell body)","04640(Hematopoietic cell lineage);04660(T cell receptor signaling pathway);04658(Th1 and Th2 cell differentiation);04659(Th17 cell differentiation);05340(Primary immunodeficiency);05166(HTLV-I infection);05162(Measles);05142(Chagas disease (American trypanosomiasis))","NA","NA","CD3e molecule [Source:HGNC Symbol;Acc:HGNC:1674]",{"v":15.433147,"d":"15.43"},{"v":22.989647,"d":"22.99"},{"v":0.67130856772181,"d":"0.67"},{"v":-0.57495203964653,"d":"-0.57"},{"v":0.430611199077669,"d":"0.43"},{"v":0.780683168983376,"d":"0.78"},"down","no"]
[123997,0,"chr20","+",44910124,44939313,"ENST00000537323",14,1910,"MSTRG.9764","PABPC1L","GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0070062(extracellular exosome);GO:0001556(oocyte maturation);GO:0006338(chromatin remodeling);GO:0006378(mRNA polyadenylation);GO:0048096(chromatin-mediated maintenance of transcription);GO:0051647(nucleus localization)","03013(RNA transport);03015(mRNA surveillance pathway);03018(RNA degradation)","K13126","NA","poly(A) binding protein cytoplasmic 1 like [Source:HGNC Symbol;Acc:HGNC:15797]",{"v":0.419298,"d":"0.42"},{"v":0.644551,"d":"0.64"},{"v":0.650527266267526,"d":"0.65"},{"v":-0.620318567406942,"d":"-0.62"},{"v":0.437535841098421,"d":"0.44"},{"v":0.786666277242327,"d":"0.79"},"down","no"]
[48963,0,"chr13","+",20567138,20691437,"ENST00000319980",28,3091,"ENSG00000032742","IFT88","GO:0005737(cytoplasm);GO:0005856(cytoskeleton);GO:0042995(cell projection);GO:0035735(intraciliary transport involved in cilium assembly);GO:0060271(cilium assembly);GO:0005929(cilium);GO:0030992(intraciliary transport particle B);GO:0097542(ciliary tip);GO:0030030(cell projection organization);GO:0005814(centriole);GO:1902017(regulation of cilium assembly);GO:0036064(ciliary basal body);GO:0005515(protein binding);GO:0031514(motile cilium);GO:2000785(regulation of autophagosome assembly)","NA","NA","NA","intraflagellar transport 88 [Source:HGNC Symbol;Acc:HGNC:20606]",{"v":1.031018,"d":"1.03"},{"v":0.746062,"d":"0.75"},{"v":1.38194680871027,"d":"1.38"},{"v":0.466702087298719,"d":"0.47"},{"v":0.443818275995969,"d":"0.44"},{"v":0.790276737567996,"d":"0.79"},"up","no"]
[70924,0,"chr16","+",24540195,24572863,"ENST00000319715",18,6229,"ENSG00000122257","RBBP6","GO:0003676(nucleic acid binding);GO:0008270(zinc ion binding);GO:0004842(ubiquitin-protein transferase activity);GO:0006397(mRNA processing);GO:0016567(protein ubiquitination);GO:0061630(ubiquitin protein ligase activity);GO:0005634(nucleus);GO:0003723(RNA binding);GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0016740(transferase activity);GO:0005694(chromosome);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0006974(cellular response to DNA damage stimulus);GO:0006260(DNA replication);GO:0005730(nucleolus);GO:0005813(centrosome);GO:0005815(microtubule organizing center);GO:0005829(cytosol);GO:0019901(protein kinase binding);GO:0000209(protein polyubiquitination);GO:0043234(protein complex);GO:0042787(protein ubiquitination involved in ubiquitin-dependent protein catabolic process);GO:0006275(regulation of DNA replication);GO:0001701(in utero embryonic development);GO:0035264(multicellular organism growth);GO:0048568(embryonic organ development);GO:0061053(somite development)","NA","NA","NA","RB binding protein 6, ubiquitin ligase [Source:HGNC Symbol;Acc:HGNC:9889]",{"v":1.277441,"d":"1.28"},{"v":1.879172,"d":"1.88"},{"v":0.679789290176737,"d":"0.68"},{"v":-0.556840461943673,"d":"-0.56"},{"v":0.449592258915562,"d":"0.45"},{"v":0.794043713605691,"d":"0.79"},"down","no"]
[108596,0,"chr2","+",32628062,32821051,"ENST00000317907",20,2876,"ENSG00000018699","TTC27","GO:0003674(molecular_function);GO:0008150(biological_process);GO:0005575(cellular_component)","NA","NA","NA","tetratricopeptide repeat domain 27 [Source:HGNC Symbol;Acc:HGNC:25986]",{"v":2.064869,"d":"2.06"},{"v":1.521904,"d":"1.52"},{"v":1.35676691828131,"d":"1.36"},{"v":0.440172898559336,"d":"0.44"},{"v":0.456370890384458,"d":"0.46"},{"v":0.798389165866205,"d":"0.80"},"up","no"]
[93277,0,"chr18","-",68688417,68691353,"ENST00000566887",2,697,"ENSG00000166479","TMX3","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016853(isomerase activity);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0045454(cell redox homeostasis);GO:0005515(protein binding);GO:0003756(protein disulfide isomerase activity);GO:0005886(plasma membrane);GO:0002576(platelet degranulation);GO:0006457(protein folding);GO:0031092(platelet alpha granule membrane);GO:0009986(cell surface);GO:0034976(response to endoplasmic reticulum stress);GO:0016972(thiol oxidase activity);GO:0018171(peptidyl-cysteine oxidation);GO:0005623(cell)","NA","NA","NA","thioredoxin related transmembrane protein 3 [Source:HGNC Symbol;Acc:HGNC:24718]",{"v":1.155064,"d":"1.16"},{"v":1.719889,"d":"1.72"},{"v":0.671592178332439,"d":"0.67"},{"v":-0.574342666796327,"d":"-0.57"},{"v":0.462980807240805,"d":"0.46"},{"v":0.803406688014634,"d":"0.80"},"down","no"]
[63667,0,"chr15","-",65442463,65517273,"ENST00000341861",20,8699,"ENSG00000074603","DPP8","GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0016787(hydrolase activity);GO:0008233(peptidase activity);GO:0006508(proteolysis);GO:0006955(immune response);GO:0008236(serine-type peptidase activity);GO:0004177(aminopeptidase activity);GO:0008239(dipeptidyl-peptidase activity)","NA","NA","NA","dipeptidyl peptidase 8 [Source:HGNC Symbol;Acc:HGNC:16490]",{"v":1.616088,"d":"1.62"},{"v":2.334191,"d":"2.33"},{"v":0.692354653068236,"d":"0.69"},{"v":-0.53041685882519,"d":"-0.53"},{"v":0.472189607138212,"d":"0.47"},{"v":0.809259469173102,"d":"0.81"},"down","no"]
[162818,0,"chr6","+",10722975,10731129,"ENST00000229563",6,1113,"MSTRG.12670","TMEM14C","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005739(mitochondrion);GO:0005515(protein binding);GO:0006783(heme biosynthetic process);GO:0031966(mitochondrial membrane)","NA","NA","NA","transmembrane protein 14C [Source:HGNC Symbol;Acc:HGNC:20952]",{"v":3.515303,"d":"3.52"},{"v":5.069932,"d":"5.07"},{"v":0.693362948457691,"d":"0.69"},{"v":-0.528317350219338,"d":"-0.53"},{"v":0.48222386384519,"d":"0.48"},{"v":0.814699820639205,"d":"0.81"},"down","no"]
[178585,0,"chr7","+",128862826,128865843,"ENST00000249289",2,704,"MSTRG.13957","ATP6V1F","GO:0006810(transport);GO:0016020(membrane);GO:0006811(ion transport);GO:0015991(ATP hydrolysis coupled proton transport);GO:0015992(proton transport);GO:0046961(proton-transporting ATPase activity, rotational mechanism);GO:0033180(proton-transporting V-type ATPase, V1 domain);GO:0034220(ion transmembrane transport);GO:0005515(protein binding);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0008286(insulin receptor signaling pathway);GO:0033572(transferrin transport);GO:0090383(phagosome acidification);GO:0015078(hydrogen ion transmembrane transporter activity);GO:0016471(vacuolar proton-transporting V-type ATPase complex);GO:0042624(ATPase activity, uncoupled);GO:0042625(ATPase coupled ion transmembrane transporter activity);GO:0016469(proton-transporting two-sector ATPase complex)","00190(Oxidative phosphorylation);04150(mTOR signaling pathway);04145(Phagosome);04966(Collecting duct acid secretion);04721(Synaptic vesicle cycle);05323(Rheumatoid arthritis);05110(Vibrio cholerae infection);05120(Epithelial cell signaling in Helicobacter pylori infection)","K02151","NA","ATPase H+ transporting V1 subunit F [Source:HGNC Symbol;Acc:HGNC:16832]",{"v":9.523778,"d":"9.52"},{"v":13.611445,"d":"13.61"},{"v":0.699688974976573,"d":"0.70"},{"v":-0.515214335651354,"d":"-0.52"},{"v":0.487953021608576,"d":"0.49"},{"v":0.818056480963591,"d":"0.82"},"down","no"]
[139720,0,"chr3","-",122531773,122564315,"ENST00000462315",10,6769,"MSTRG.11137","PARP9","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0016740(transferase activity);GO:0005739(mitochondrion);GO:0006281(DNA repair);GO:0006974(cellular response to DNA damage stimulus);GO:0003950(NAD+ ADP-ribosyltransferase activity);GO:0005515(protein binding);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0016477(cell migration);GO:0006302(double-strand break repair);GO:0034356(NAD biosynthesis via nicotinamide riboside salvage pathway);GO:0001191(transcriptional repressor activity, RNA polymerase II transcription factor binding);GO:0060330(regulation of response to interferon-gamma)","NA","NA","NA","poly(ADP-ribose) polymerase family member 9 [Source:HGNC Symbol;Acc:HGNC:24118]",{"v":2.727744,"d":"2.73"},{"v":2.076703,"d":"2.08"},{"v":1.31349740429903,"d":"1.31"},{"v":0.393413349456224,"d":"0.39"},{"v":0.494024677240094,"d":"0.49"},{"v":0.820772383870708,"d":"0.82"},"up","no"]
[169827,0,"chr6","+",143536845,143824164,"ENST00000367584",12,2490,"MSTRG.13324","PHACTR2","GO:0003779(actin binding);GO:0043086(negative regulation of catalytic activity);GO:0004864(protein phosphatase inhibitor activity);GO:0016020(membrane);GO:0005515(protein binding);GO:0005886(plasma membrane);GO:0002576(platelet degranulation);GO:0031092(platelet alpha granule membrane)","NA","NA","NA","phosphatase and actin regulator 2 [Source:HGNC Symbol;Acc:HGNC:20956]",{"v":1.542719,"d":"1.54"},{"v":2.196858,"d":"2.20"},{"v":0.7022388338254,"d":"0.70"},{"v":-0.509966315390152,"d":"-0.51"},{"v":0.499852921240883,"d":"0.50"},{"v":0.823773537088695,"d":"0.82"},"down","no"]
[81650,0,"chr17","-",30194321,30235968,"ENST00000261707",15,6604,"ENSG00000108576","SLC6A4","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0046872(metal ion binding);GO:0005887(integral component of plasma membrane);GO:0005829(cytosol);GO:0015293(symporter activity);GO:0055085(transmembrane transport);GO:0005886(plasma membrane);GO:0005328(neurotransmitter:sodium symporter activity);GO:0006836(neurotransmitter transport);GO:0098793(presynapse);GO:0045121(membrane raft);GO:0072488(ammonium transmembrane transport);GO:0005515(protein binding);GO:0005768(endosome);GO:0051015(actin filament binding);GO:0012505(endomembrane system);GO:0010008(endosome membrane);GO:0043005(neuron projection);GO:0005335(serotonin:sodium symporter activity);GO:0051259(protein oligomerization);GO:0009636(response to toxic substance);GO:0042136(neurotransmitter biosynthetic process);GO:0017137(Rab GTPase binding);GO:0035176(social behavior);GO:0008504(monoamine transmembrane transporter activity);GO:0015844(monoamine transport);GO:0005330(dopamine:sodium symporter activity);GO:0015222(serotonin transmembrane transporter activity);GO:0006837(serotonin transport);GO:0021794(thalamus development);GO:0046621(negative regulation of organ growth);GO:0048854(brain morphogenesis);GO:0051583(dopamine uptake involved in synaptic transmission);GO:0051610(serotonin uptake);GO:0017022(myosin binding);GO:0017075(syntaxin-1 binding);GO:0019811(cocaine binding);GO:0042803(protein homodimerization activity);GO:0050998(nitric-oxide synthase binding);GO:0001666(response to hypoxia);GO:0007420(brain development);GO:0007584(response to nutrient);GO:0007613(memory);GO:0007623(circadian rhythm);GO:0010033(response to organic substance);GO:0010628(positive regulation of gene expression);GO:0014064(positive regulation of serotonin secretion);GO:0021941(negative regulation of cerebellar granule cell precursor proliferation);GO:0032227(negative regulation of synaptic transmission, dopaminergic);GO:0032355(response to estradiol);GO:0042310(vasoconstriction);GO:0042493(response to drug);GO:0042713(sperm ejaculation);GO:0045665(negative regulation of neuron differentiation);GO:0045787(positive regulation of cell cycle);GO:0051260(protein homooligomerization);GO:0071300(cellular response to retinoic acid);GO:0071310(cellular response to organic substance);GO:0071321(cellular response to cGMP)","04726(Serotonergic synapse)","K05037","NA","solute carrier family 6 member 4 [Source:HGNC Symbol;Acc:HGNC:11050]",{"v":0.23916,"d":"0.24"},{"v":0.340603,"d":"0.34"},{"v":0.702166451851569,"d":"0.70"},{"v":-0.510115026187317,"d":"-0.51"},{"v":0.504154054950496,"d":"0.50"},{"v":0.824962427518795,"d":"0.82"},"down","no"]
[30354,0,"chr11","+",62789060,62790110,"ENST00000532345",2,845,"MSTRG.2478","TMEM179B","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016607(nuclear speck);GO:0005730(nucleolus);GO:0005886(plasma membrane);GO:0043312(neutrophil degranulation);GO:0030667(secretory granule membrane);GO:0035577(azurophil granule membrane);GO:0101003(ficolin-1-rich granule membrane)","NA","NA","NA","transmembrane protein 179B [Source:HGNC Symbol;Acc:HGNC:33744]",{"v":2.312569,"d":"2.31"},{"v":1.757152,"d":"1.76"},{"v":1.3160893309173,"d":"1.32"},{"v":0.396257416806781,"d":"0.40"},{"v":0.510326804804066,"d":"0.51"},{"v":0.827798995802404,"d":"0.83"},"up","no"]
[88009,0,"chr17","+",75490280,75492278,"ENST00000579241",5,986,"ENSG00000177728","TMEM94","GO:0016020(membrane);GO:0016021(integral component of membrane)","NA","NA","NA","transmembrane protein 94 [Source:HGNC Symbol;Acc:HGNC:28983]",{"v":0.987108,"d":"0.99"},{"v":0.734918,"d":"0.73"},{"v":1.34315393009832,"d":"1.34"},{"v":0.425624652095045,"d":"0.43"},{"v":0.516758505117322,"d":"0.52"},{"v":0.831855763323971,"d":"0.83"},"up","no"]
[21351,0,"chr10","-",73806876,73807524,"ENST00000463410",2,461,"MSTRG.1813","NDST2","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016740(transferase activity);GO:0016787(hydrolase activity);GO:0005794(Golgi apparatus);GO:0003824(catalytic activity);GO:0008152(metabolic process);GO:0000139(Golgi membrane);GO:0008146(sulfotransferase activity);GO:0015016([heparan sulfate]-glucosamine N-sulfotransferase activity);GO:0006024(glycosaminoglycan biosynthetic process);GO:0015012(heparan sulfate proteoglycan biosynthetic process);GO:0030210(heparin biosynthetic process);GO:0050119(N-acetylglucosamine deacetylase activity)","00534(Glycosaminoglycan biosynthesis - heparan sulfate / heparin)","NA","NA","N-deacetylase and N-sulfotransferase 2 [Source:HGNC Symbol;Acc:HGNC:7681]",{"v":2.162,"d":"2.16"},{"v":1.623267,"d":"1.62"},{"v":1.3318819393236,"d":"1.33"},{"v":0.413466204705614,"d":"0.41"},{"v":0.527796956740684,"d":"0.53"},{"v":0.835854593474805,"d":"0.84"},"up","no"]
[11183,0,"chr1","-",153662036,153671048,"ENST00000361891",14,1659,"MSTRG.974","ILF2","GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005524(ATP binding);GO:0005730(nucleolus);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0030529(intracellular ribonucleoprotein complex);GO:0005515(protein binding);GO:0006955(immune response);GO:0016740(transferase activity);GO:0045893(positive regulation of transcription, DNA-templated);GO:0005576(extracellular region);GO:0043312(neutrophil degranulation);GO:1904813(ficolin-1-rich granule lumen);GO:0035580(specific granule lumen);GO:1904724(tertiary granule lumen);GO:0003725(double-stranded RNA binding)","NA","NA","NA","interleukin enhancer binding factor 2 [Source:HGNC Symbol;Acc:HGNC:6037]",{"v":29.381239,"d":"29.38"},{"v":23.030378,"d":"23.03"},{"v":1.27576017206491,"d":"1.28"},{"v":0.351357144861079,"d":"0.35"},{"v":0.532801957086308,"d":"0.53"},{"v":0.838243734565033,"d":"0.84"},"up","no"]
[83039,0,"chr17","+",40062810,40093867,"ENST00000264637",10,2538,"MSTRG.6801","THRA","GO:0005634(nucleus);GO:0008270(zinc ion binding);GO:0006355(regulation of transcription, DNA-templated);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0043565(sequence-specific DNA binding);GO:0046872(metal ion binding);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0030522(intracellular receptor signaling pathway);GO:0007165(signal transduction);GO:0004887(thyroid hormone receptor activity);GO:0005829(cytosol);GO:0005515(protein binding);GO:0003707(steroid hormone receptor activity);GO:0043401(steroid hormone mediated signaling pathway);GO:0005654(nucleoplasm);GO:0006366(transcription from RNA polymerase II promoter);GO:0019904(protein domain specific binding);GO:0008134(transcription factor binding);GO:0045892(negative regulation of transcription, DNA-templated);GO:0006367(transcription initiation from RNA polymerase II promoter);GO:0044212(transcription regulatory region DNA binding);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0017055(negative regulation of RNA polymerase II transcriptional preinitiation complex assembly);GO:0070324(thyroid hormone binding);GO:0017025(TBP-class protein binding);GO:0009755(hormone-mediated signaling pathway);GO:2000143(negative regulation of DNA-templated transcription, initiation);GO:0000976(transcription regulatory region sequence-specific DNA binding);GO:0002153(steroid receptor RNA activator RNA binding);GO:0003727(single-stranded RNA binding);GO:0004879(RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding);GO:0031490(chromatin DNA binding);GO:0032403(protein complex binding);GO:0001502(cartilage condensation);GO:0001503(ossification);GO:0002155(regulation of thyroid hormone mediated signaling pathway);GO:0007611(learning or memory);GO:0008016(regulation of heart contraction);GO:0008050(female courtship behavior);GO:0009409(response to cold);GO:0009887(animal organ morphogenesis);GO:0010831(positive regulation of myotube differentiation);GO:0030218(erythrocyte differentiation);GO:0030878(thyroid gland development);GO:0033032(regulation of myeloid cell apoptotic process);GO:0042994(cytoplasmic sequestering of transcription factor);GO:0045925(positive regulation of female receptivity);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0050994(regulation of lipid catabolic process);GO:0060509(Type I pneumocyte differentiation);GO:0005737(cytoplasm)","04080(Neuroactive ligand-receptor interaction);04919(Thyroid hormone signaling pathway)","K05547","NA","thyroid hormone receptor, alpha [Source:HGNC Symbol;Acc:HGNC:11796]",{"v":2.411379,"d":"2.41"},{"v":1.891147,"d":"1.89"},{"v":1.2750880814659,"d":"1.28"},{"v":0.350596910068348,"d":"0.35"},{"v":0.541100421413518,"d":"0.54"},{"v":0.843678964044293,"d":"0.84"},"up","no"]
[136148,0,"chr3","-",49095939,49104532,"ENST00000464962",23,2362,"MSTRG.10927","QARS","GO:0005737(cytoplasm);GO:0006412(translation);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0005829(cytosol);GO:0016874(ligase activity);GO:0004812(aminoacyl-tRNA ligase activity);GO:0006418(tRNA aminoacylation for protein translation);GO:0016876(ligase activity, forming aminoacyl-tRNA and related compounds);GO:0043039(tRNA aminoacylation);GO:0005515(protein binding);GO:0004819(glutamine-tRNA ligase activity);GO:0006425(glutaminyl-tRNA aminoacylation);GO:0005759(mitochondrial matrix);GO:0043234(protein complex);GO:0007420(brain development);GO:0017101(aminoacyl-tRNA synthetase multienzyme complex);GO:0045892(negative regulation of transcription, DNA-templated);GO:0019901(protein kinase binding);GO:0006469(negative regulation of protein kinase activity);GO:0004860(protein kinase inhibitor activity);GO:0032873(negative regulation of stress-activated MAPK cascade);GO:2001234(negative regulation of apoptotic signaling pathway);GO:0016020(membrane);GO:0016021(integral component of membrane)","00970(Aminoacyl-tRNA biosynthesis)","NA","NA","glutaminyl-tRNA synthetase [Source:HGNC Symbol;Acc:HGNC:9751]",{"v":3.459395,"d":"3.46"},{"v":2.728991,"d":"2.73"},{"v":1.26764617398885,"d":"1.27"},{"v":0.34215211593052,"d":"0.34"},{"v":0.549088298758571,"d":"0.55"},{"v":0.848994997556405,"d":"0.85"},"up","no"]
[102499,0,"chr19","-",44286350,44305025,"ENST00000291182",5,3188,"ENSG00000159917","ZNF235","GO:0003676(nucleic acid binding);GO:0006355(regulation of transcription, DNA-templated);GO:0005622(intracellular);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0045892(negative regulation of transcription, DNA-templated)","NA","NA","NA","zinc finger protein 235 [Source:HGNC Symbol;Acc:HGNC:12866]",{"v":1.045361,"d":"1.05"},{"v":0.825746,"d":"0.83"},{"v":1.26595950812962,"d":"1.27"},{"v":0.340231260726104,"d":"0.34"},{"v":0.555276314183212,"d":"0.56"},{"v":0.852181537076137,"d":"0.85"},"up","no"]
[22657,0,"chr10","-",97458324,97467525,"ENST00000434538",18,2164,"MSTRG.1898","MMS19","GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0006281(DNA repair);GO:0006974(cellular response to DNA damage stimulus);GO:0003713(transcription coactivator activity);GO:0045893(positive regulation of transcription, DNA-templated);GO:0016226(iron-sulfur cluster assembly);GO:0005819(spindle);GO:0007059(chromosome segregation);GO:0030331(estrogen receptor binding);GO:0030674(protein binding, bridging);GO:0030159(receptor signaling complex scaffold activity);GO:0071817(MMXD complex);GO:0097361(CIA complex);GO:0006259(DNA metabolic process);GO:0009725(response to hormone);GO:0006289(nucleotide-excision repair);GO:0005675(holo TFIIH complex);GO:0000160(phosphorelay signal transduction system);GO:0019899(enzyme binding)","NA","NA","NA","MMS19 homolog, cytosolic iron-sulfur assembly component [Source:HGNC Symbol;Acc:HGNC:13824]",{"v":0.328686,"d":"0.33"},{"v":0.466604,"d":"0.47"},{"v":0.704421736633205,"d":"0.70"},{"v":-0.505488667193125,"d":"-0.51"},{"v":0.561205739701937,"d":"0.56"},{"v":0.855562391996357,"d":"0.86"},"down","no"]
[58457,0,"chr14","+",100238985,100282792,"ENST00000262238",5,6697,"MSTRG.4672","YY1","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0006281(DNA repair);GO:0006310(DNA recombination);GO:0006974(cellular response to DNA damage stimulus);GO:0030154(cell differentiation);GO:0007283(spermatogenesis);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0005654(nucleoplasm);GO:0016579(protein deubiquitination);GO:0001158(enhancer sequence-specific DNA binding);GO:0003713(transcription coactivator activity);GO:0000400(four-way junction DNA binding);GO:0016363(nuclear matrix);GO:0003714(transcription corepressor activity);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0000724(double-strand break repair via homologous recombination);GO:0001078(transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0008270(zinc ion binding);GO:0000987(core promoter proximal region sequence-specific DNA binding);GO:0032688(negative regulation of interferon-beta production);GO:0003723(RNA binding);GO:0031011(Ino80 complex);GO:0034644(cellular response to UV);GO:0044212(transcription regulatory region DNA binding);GO:0010225(response to UV-C);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:0042826(histone deacetylase binding);GO:0043565(sequence-specific DNA binding);GO:0046332(SMAD binding);GO:0006403(RNA localization);GO:0009952(anterior/posterior pattern specification);GO:0010628(positive regulation of gene expression);GO:0010629(negative regulation of gene expression);GO:0034696(response to prostaglandin F);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0048593(camera-type eye morphogenesis);GO:0051276(chromosome organization);GO:0071347(cellular response to interleukin-1);GO:1902894(negative regulation of pri-miRNA transcription from RNA polymerase II promoter);GO:0000790(nuclear chromatin);GO:0005667(transcription factor complex);GO:0005737(cytoplasm);GO:0031519(PcG protein complex)","NA","NA","NA","YY1 transcription factor [Source:HGNC Symbol;Acc:HGNC:12856]",{"v":10.435191,"d":"10.44"},{"v":8.381364,"d":"8.38"},{"v":1.24504686826631,"d":"1.25"},{"v":0.31620005180556,"d":"0.32"},{"v":0.568531813712805,"d":"0.57"},{"v":0.859443081920311,"d":"0.86"},"up","no"]
[9098,0,"chr1","-",110947185,110964079,"ENST00000369763",4,3475,"ENSG00000121931","LRIF1","GO:0005634(nucleus);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0005515(protein binding);GO:0005815(microtubule organizing center);GO:0000784(nuclear chromosome, telomeric region);GO:0016363(nuclear matrix);GO:0042974(retinoic acid receptor binding)","NA","NA","NA","ligand dependent nuclear receptor interacting factor 1 [Source:HGNC Symbol;Acc:HGNC:30299]",{"v":3.182065,"d":"3.18"},{"v":4.262403,"d":"4.26"},{"v":0.746542501964268,"d":"0.75"},{"v":-0.421703697049192,"d":"-0.42"},{"v":0.581470711162119,"d":"0.58"},{"v":0.865751260302974,"d":"0.87"},"down","no"]
[42127,0,"chr12","+",53295552,53299450,"ENST00000334478",6,586,"MSTRG.3398","PFDN5","GO:0090090(negative regulation of canonical Wnt signaling pathway);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0006457(protein folding);GO:0005515(protein binding);GO:0051082(unfolded protein binding);GO:0016272(prefoldin complex);GO:0003714(transcription corepressor activity);GO:0045892(negative regulation of transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0060041(retina development in camera-type eye)","NA","NA","NA","prefoldin subunit 5 [Source:HGNC Symbol;Acc:HGNC:8869]",{"v":140.113251,"d":"140.11"},{"v":114.04306,"d":"114.04"},{"v":1.22859953950727,"d":"1.23"},{"v":0.297014747676475,"d":"0.30"},{"v":0.588408318639883,"d":"0.59"},{"v":0.869065462112559,"d":"0.87"},"up","no"]
[74726,0,"chr16","-",67987397,68000586,"ENST00000575203",12,2248,"MSTRG.6048","DPEP2","GO:0016020(membrane);GO:0046872(metal ion binding);GO:0016787(hydrolase activity);GO:0008233(peptidase activity);GO:0006508(proteolysis);GO:0008237(metallopeptidase activity);GO:0008235(metalloexopeptidase activity);GO:0008239(dipeptidyl-peptidase activity);GO:0016805(dipeptidase activity);GO:0031225(anchored component of membrane);GO:0008238(exopeptidase activity)","NA","NA","NA","dipeptidase 2 [Source:HGNC Symbol;Acc:HGNC:23028]",{"v":1.184902,"d":"1.18"},{"v":1.584121,"d":"1.58"},{"v":0.747987054019232,"d":"0.75"},{"v":-0.41891479437857,"d":"-0.42"},{"v":0.594005031287139,"d":"0.59"},{"v":0.87121511494658,"d":"0.87"},"down","no"]
[29385,0,"chr11","+",57712614,57740969,"ENST00000529403",8,1697,"MSTRG.2414","TMX2","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0003674(molecular_function);GO:0008150(biological_process);GO:0005575(cellular_component);GO:0005623(cell);GO:0045454(cell redox homeostasis)","NA","NA","NA","thioredoxin related transmembrane protein 2 [Source:HGNC Symbol;Acc:HGNC:30739]",{"v":0.891501,"d":"0.89"},{"v":0.716863,"d":"0.72"},{"v":1.24361419127504,"d":"1.24"},{"v":0.314538984935157,"d":"0.31"},{"v":0.600215128556453,"d":"0.60"},{"v":0.874632977232377,"d":"0.87"},"up","no"]
[84944,0,"chr17","+",47971125,47981768,"ENST00000585163",13,2519,"MSTRG.6978","CDK5RAP3","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005730(nucleolus);GO:0005829(cytosol);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0005874(microtubule);GO:0005813(centrosome);GO:0005815(microtubule organizing center);GO:0012505(endomembrane system);GO:0019901(protein kinase binding);GO:0008283(cell proliferation);GO:0032088(negative regulation of NF-kappaB transcription factor activity);GO:0031398(positive regulation of protein ubiquitination);GO:0043234(protein complex);GO:0001933(negative regulation of protein phosphorylation);GO:0007095(mitotic G2 DNA damage checkpoint);GO:0007420(brain development);GO:0051019(mitogen-activated protein kinase binding);GO:0030332(cyclin binding);GO:0051059(NF-kappaB binding);GO:0043407(negative regulation of MAP kinase activity);GO:0071901(negative regulation of protein serine/threonine kinase activity);GO:0071569(protein ufmylation);GO:0030968(endoplasmic reticulum unfolded protein response);GO:0010921(regulation of phosphatase activity);GO:1900182(positive regulation of protein localization to nucleus);GO:0044387(negative regulation of protein kinase activity by regulation of protein phosphorylation);GO:0000079(regulation of cyclin-dependent protein serine/threonine kinase activity);GO:0097371(MDM2/MDM4 family protein binding);GO:0045664(regulation of neuron differentiation);GO:0030262(apoptotic nuclear changes);GO:1903363(negative regulation of cellular protein catabolic process);GO:1901798(positive regulation of signal transduction by p53 class mediator);GO:0044389(ubiquitin-like protein ligase binding);GO:0044818(mitotic G2/M transition checkpoint);GO:0045944(positive regulation of transcription from RNA polymerase II promoter)","NA","NA","NA","CDK5 regulatory subunit associated protein 3 [Source:HGNC Symbol;Acc:HGNC:18673]",{"v":4.813876,"d":"4.81"},{"v":3.963934,"d":"3.96"},{"v":1.21441880717489,"d":"1.21"},{"v":0.280266038428476,"d":"0.28"},{"v":0.609836954132174,"d":"0.61"},{"v":0.879233105378274,"d":"0.88"},"up","no"]
[180104,0,"chr7","-",150791287,150800364,"ENST00000326442",7,1129,"MSTRG.14131","TMEM176B","GO:0005634(nucleus);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0030154(cell differentiation);GO:0031965(nuclear membrane);GO:0009887(animal organ morphogenesis);GO:2001199(negative regulation of dendritic cell differentiation)","NA","NA","NA","transmembrane protein 176B [Source:HGNC Symbol;Acc:HGNC:29596]",{"v":25.92989,"d":"25.93"},{"v":33.976059,"d":"33.98"},{"v":0.763181215337541,"d":"0.76"},{"v":-0.38990243307341,"d":"-0.39"},{"v":0.612729574321713,"d":"0.61"},{"v":0.880006356671416,"d":"0.88"},"down","no"]
[124204,0,"chr20","+",45792055,45811427,"ENST00000456939",12,1073,"MSTRG.9775","DNTTIP1","GO:0005634(nucleus);GO:0005730(nucleolus);GO:0005654(nucleoplasm);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0042803(protein homodimerization activity);GO:0005515(protein binding);GO:0000118(histone deacetylase complex);GO:0031491(nucleosome binding)","NA","NA","NA","deoxynucleotidyltransferase terminal interacting protein 1 [Source:HGNC Symbol;Acc:HGNC:16160]",{"v":1.865404,"d":"1.87"},{"v":1.528011,"d":"1.53"},{"v":1.22080534760548,"d":"1.22"},{"v":0.287833186868151,"d":"0.29"},{"v":0.618993272363931,"d":"0.62"},{"v":0.883239792951478,"d":"0.88"},"up","no"]
[64928,0,"chr15","-",75357735,75363177,"ENST00000564785",4,4820,"MSTRG.5311","MAN2C1","GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0005654(nucleoplasm);GO:0030246(carbohydrate binding);GO:0016787(hydrolase activity);GO:0003824(catalytic activity);GO:0005975(carbohydrate metabolic process);GO:0008152(metabolic process);GO:0016798(hydrolase activity, acting on glycosyl bonds);GO:0004559(alpha-mannosidase activity);GO:0006013(mannose metabolic process);GO:0005829(cytosol);GO:0006517(protein deglycosylation);GO:0009313(oligosaccharide catabolic process);GO:0005773(vacuole)","00511(Other glycan degradation)","NA","NA","mannosidase alpha class 2C member 1 [Source:HGNC Symbol;Acc:HGNC:6827]",{"v":0.459488,"d":"0.46"},{"v":0.378019,"d":"0.38"},{"v":1.21551562223063,"d":"1.22"},{"v":0.281568435505532,"d":"0.28"},{"v":0.625437924457508,"d":"0.63"},{"v":0.88555350241246,"d":"0.89"},"up","no"]
[937,0,"chr1","-",3889125,3900293,"ENST00000474140",3,3499,"MSTRG.95","C1orf174","GO:0005634(nucleus);GO:0005515(protein binding)","NA","NA","NA","chromosome 1 open reading frame 174 [Source:HGNC Symbol;Acc:HGNC:27915]",{"v":0.538788,"d":"0.54"},{"v":0.698146,"d":"0.70"},{"v":0.771741154429016,"d":"0.77"},{"v":-0.373811052886971,"d":"-0.37"},{"v":0.638668828194293,"d":"0.64"},{"v":0.891320296485838,"d":"0.89"},"down","no"]
[111354,0,"chr2","-",74527736,74528936,"ENST00000464887",3,845,"MSTRG.8842","AUP1","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0050790(regulation of catalytic activity);GO:0005515(protein binding);GO:0030970(retrograde protein transport, ER to cytosol);GO:0070062(extracellular exosome);GO:0030176(integral component of endoplasmic reticulum membrane);GO:0043130(ubiquitin binding);GO:0030433(ubiquitin-dependent ERAD pathway);GO:0097027(ubiquitin-protein transferase activator activity);GO:0000839(Hrd1p ubiquitin ligase ERAD-L complex)","NA","NA","NA","ancient ubiquitous protein 1 [Source:HGNC Symbol;Acc:HGNC:891]",{"v":2.997056,"d":"3.00"},{"v":2.508588,"d":"2.51"},{"v":1.19471830368319,"d":"1.19"},{"v":0.256670492861076,"d":"0.26"},{"v":0.646482016492725,"d":"0.65"},{"v":0.895432841057032,"d":"0.90"},"up","no"]
[10465,0,"chr1","-",149884459,149886652,"ENST00000369155",1,2194,"MSTRG.892","HIST2H2BE","GO:0005634(nucleus);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0003677(DNA binding);GO:0046982(protein heterodimerization activity);GO:0006334(nucleosome assembly);GO:0000786(nucleosome);GO:0005694(chromosome);GO:0005615(extracellular space);GO:0042742(defense response to bacterium);GO:0070062(extracellular exosome);GO:0002227(innate immune response in mucosa);GO:0019731(antibacterial humoral response);GO:0050830(defense response to Gram-positive bacterium);GO:0061844(antimicrobial humoral immune response mediated by antimicrobial peptide)","05203(Viral carcinogenesis);05322(Systemic lupus erythematosus);05034(Alcoholism)","K11252","NA","histone cluster 2 H2B family member e [Source:HGNC Symbol;Acc:HGNC:4760]",{"v":21.038193,"d":"21.04"},{"v":26.864443,"d":"26.86"},{"v":0.783124109440869,"d":"0.78"},{"v":-0.352687131067034,"d":"-0.35"},{"v":0.652374073533345,"d":"0.65"},{"v":0.897759955675409,"d":"0.90"},"down","no"]
[10679,0,"chr1","+",150962128,150963082,"ENST00000528749",2,527,"MSTRG.932","SETDB1","GO:0005634(nucleus);GO:0043231(intracellular membrane-bounded organelle);GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0008168(methyltransferase activity);GO:0016740(transferase activity);GO:0032259(methylation);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0016569(covalent chromatin modification);GO:0003677(DNA binding);GO:0005886(plasma membrane);GO:0005694(chromosome);GO:0005515(protein binding);GO:0018024(histone-lysine N-methyltransferase activity);GO:0034968(histone lysine methylation);GO:0007265(Ras protein signal transduction);GO:0003682(chromatin binding);GO:1990841(promoter-specific chromatin binding);GO:0090309(positive regulation of methylation-dependent chromatin silencing);GO:0033273(response to vitamin);GO:0045471(response to ethanol)","00310(Lysine degradation);04550(Signaling pathways regulating pluripotency of stem cells)","NA","NA","SET domain bifurcated 1 [Source:HGNC Symbol;Acc:HGNC:10761]",{"v":1.379101,"d":"1.38"},{"v":1.817104,"d":"1.82"},{"v":0.758955458795974,"d":"0.76"},{"v":-0.397912874937975,"d":"-0.40"},{"v":0.657234558071443,"d":"0.66"},{"v":0.898942369721938,"d":"0.90"},"down","no"]
[60443,0,"chr15","-",30403740,30414162,"ENST00000327271",19,1896,"ENSG00000186399","GOLGA8R","GO:0005794(Golgi apparatus)","NA","NA","NA","golgin A8 family member R [Source:HGNC Symbol;Acc:HGNC:44407]",{"v":0.813202,"d":"0.81"},{"v":0.684537,"d":"0.68"},{"v":1.18795916071739,"d":"1.19"},{"v":0.248485240479397,"d":"0.25"},{"v":0.664254975475448,"d":"0.66"},{"v":0.901872805486758,"d":"0.90"},"up","no"]
[201173,0,"chrX","+",154379197,154381523,"ENST00000369842",6,1379,"MSTRG.15499","EMD","GO:0048147(negative regulation of fibroblast proliferation);GO:0005634(nucleus);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005783(endoplasmic reticulum);GO:0031965(nuclear membrane);GO:0003779(actin binding);GO:0005515(protein binding);GO:0005874(microtubule);GO:0005635(nuclear envelope);GO:0045296(cadherin binding);GO:0005637(nuclear inner membrane);GO:0006936(muscle contraction);GO:0032541(cortical endoplasmic reticulum);GO:0048487(beta-tubulin binding);GO:0005737(cytoplasm);GO:0007517(muscle organ development);GO:0007077(mitotic nuclear envelope disassembly);GO:0071363(cellular response to growth factor stimulus);GO:0035414(negative regulation of catenin import into nucleus);GO:0060828(regulation of canonical Wnt signaling pathway);GO:0007084(mitotic nuclear envelope reassembly);GO:0046827(positive regulation of protein export from nucleus);GO:0005654(nucleoplasm);GO:0031616(spindle pole centrosome);GO:0005640(nuclear outer membrane);GO:0035914(skeletal muscle cell differentiation)","05410(Hypertrophic cardiomyopathy (HCM));05412(Arrhythmogenic right ventricular cardiomyopathy (ARVC));05414(Dilated cardiomyopathy (DCM))","K12569","NA","emerin [Source:HGNC Symbol;Acc:HGNC:3331]",{"v":11.151097,"d":"11.15"},{"v":14.055183,"d":"14.06"},{"v":0.793379709108021,"d":"0.79"},{"v":-0.333916594232465,"d":"-0.33"},{"v":0.674577198133724,"d":"0.67"},{"v":0.906701500560999,"d":"0.91"},"down","no"]
[155556,0,"chr5","-",69898867,69903198,"ENST00000505635",1,4332,"ENSG00000251158","AC131392.2","NA","NA","NA","NA","NA",{"v":0.483095,"d":"0.48"},{"v":0.615936,"d":"0.62"},{"v":0.784326618349958,"d":"0.78"},{"v":-0.350473531686381,"d":"-0.35"},{"v":0.676303244120494,"d":"0.68"},{"v":0.906945814546543,"d":"0.91"},"down","no"]
[139735,0,"chr3","+",122700526,122722647,"ENST00000474669",10,5229,"MSTRG.11139","PARP14","GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005829(cytosol);GO:0016740(transferase activity);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0016757(transferase activity, transferring glycosyl groups);GO:0003950(NAD+ ADP-ribosyltransferase activity);GO:0005515(protein binding)","NA","NA","NA","poly(ADP-ribose) polymerase family member 14 [Source:HGNC Symbol;Acc:HGNC:29232]",{"v":0.298466,"d":"0.30"},{"v":0.253731,"d":"0.25"},{"v":1.17630876794716,"d":"1.18"},{"v":0.234266801260292,"d":"0.23"},{"v":0.683632429720609,"d":"0.68"},{"v":0.910172846823651,"d":"0.91"},"up","no"]
[83828,0,"chr17","+",43006740,43014456,"ENST00000438323",7,1232,"MSTRG.6849","IFI35","GO:0005634(nucleus);GO:0005515(protein binding);GO:0005829(cytosol);GO:0060337(type I interferon signaling pathway)","NA","NA","NA","interferon induced protein 35 [Source:HGNC Symbol;Acc:HGNC:5399]",{"v":6.650391,"d":"6.65"},{"v":8.273604,"d":"8.27"},{"v":0.803808231575985,"d":"0.80"},{"v":-0.315076743177386,"d":"-0.32"},{"v":0.697768672687103,"d":"0.70"},{"v":0.916371475743992,"d":"0.92"},"down","no"]
[162381,0,"chr6","-",1623806,2245692,"ENST00000380815",11,1752,"ENSG00000112699","GMDS","GO:0005737(cytoplasm);GO:0016829(lyase activity);GO:0005515(protein binding);GO:0007219(Notch signaling pathway);GO:0042802(identical protein binding);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0008446(GDP-mannose 4,6-dehydratase activity);GO:0070401(NADP+ binding);GO:0019673(GDP-mannose metabolic process);GO:0042351('de novo' GDP-L-fucose biosynthetic process)","00051(Fructose and mannose metabolism);00520(Amino sugar and nucleotide sugar metabolism)","K01711","EC:4.2.1.47","GDP-mannose 4,6-dehydratase [Source:HGNC Symbol;Acc:HGNC:4369]",{"v":3.536189,"d":"3.54"},{"v":3.091575,"d":"3.09"},{"v":1.14381472226939,"d":"1.14"},{"v":0.193853379991444,"d":"0.19"},{"v":0.705541565669281,"d":"0.71"},{"v":0.920086297176355,"d":"0.92"},"up","no"]
[167847,0,"chr6","-",90513573,90587045,"ENST00000369332",16,4830,"MSTRG.13162","MAP3K7","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0016740(transferase activity);GO:0000287(magnesium ion binding);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0007165(signal transduction);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0006915(apoptotic process);GO:0004709(MAP kinase kinase kinase activity);GO:0038095(Fc-epsilon receptor signaling pathway);GO:0005829(cytosol);GO:0010008(endosome membrane);GO:0002223(stimulatory C-type lectin receptor signaling pathway);GO:0016579(protein deubiquitination);GO:0050852(T cell receptor signaling pathway);GO:0050870(positive regulation of T cell activation);GO:0042802(identical protein binding);GO:0043123(positive regulation of I-kappaB kinase/NF-kappaB signaling);GO:0002755(MyD88-dependent toll-like receptor signaling pathway);GO:0007249(I-kappaB kinase/NF-kappaB signaling);GO:0007250(activation of NF-kappaB-inducing kinase activity);GO:0016239(positive regulation of macroautophagy);GO:0007179(transforming growth factor beta receptor signaling pathway);GO:0007254(JNK cascade);GO:0051403(stress-activated MAPK cascade);GO:0097110(scaffold protein binding);GO:0051092(positive regulation of NF-kappaB transcription factor activity);GO:0070423(nucleotide-binding oligomerization domain containing signaling pathway);GO:0008385(IkappaB kinase complex);GO:0000187(activation of MAPK activity);GO:0000186(activation of MAPKK activity);GO:0002726(positive regulation of T cell cytokine production);GO:0007223(Wnt signaling pathway, calcium modulating pathway);GO:0007252(I-kappaB phosphorylation);GO:0032743(positive regulation of interleukin-2 production);GO:0043276(anoikis);GO:0043507(positive regulation of JUN kinase activity);GO:0043966(histone H3 acetylation);GO:0005671(Ada2/Gcn5/Ada3 transcription activator complex)","04010(MAPK signaling pathway);04310(Wnt signaling pathway);04064(NF-kappa B signaling pathway);04668(TNF signaling pathway);04152(AMPK signaling pathway);04140(Autophagy - animal);04520(Adherens junction);04620(Toll-like receptor signaling pathway);04621(NOD-like receptor signaling pathway);04622(RIG-I-like receptor signaling pathway);04660(T cell receptor signaling pathway);04657(IL-17 signaling pathway);04380(Osteoclast differentiation);05418(Fluid shear stress and atherosclerosis);05162(Measles);05168(Herpes simplex infection);05169(Epstein-Barr virus infection);05145(Toxoplasmosis);05140(Leishmaniasis)","K04427","EC:2.7.11.25","mitogen-activated protein kinase kinase kinase 7 [Source:HGNC Symbol;Acc:HGNC:6859]",{"v":4.159893,"d":"4.16"},{"v":3.653643,"d":"3.65"},{"v":1.1385603355336,"d":"1.14"},{"v":0.187210745992477,"d":"0.19"},{"v":0.710424665926235,"d":"0.71"},{"v":0.920851961681769,"d":"0.92"},"up","no"]
[159096,0,"chr5","-",140245039,140303121,"ENST00000261813",4,1352,"MSTRG.12378","PFDN1","GO:0006457(protein folding);GO:0006355(regulation of transcription, DNA-templated);GO:0051082(unfolded protein binding);GO:0005737(cytoplasm);GO:0016272(prefoldin complex);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0007010(cytoskeleton organization);GO:0044183(protein binding involved in protein folding);GO:0007049(cell cycle)","NA","NA","NA","prefoldin subunit 1 [Source:HGNC Symbol;Acc:HGNC:8866]",{"v":4.900741,"d":"4.90"},{"v":6.033692,"d":"6.03"},{"v":0.812229228803857,"d":"0.81"},{"v":-0.300041150004298,"d":"-0.30"},{"v":0.716386664193079,"d":"0.72"},{"v":0.923042022608693,"d":"0.92"},"down","no"]
[16812,0,"chr1","+",228487061,228495766,"ENST00000305943",4,3017,"MSTRG.1441","RNF187","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0016740(transferase activity);GO:0016567(protein ubiquitination);GO:0045893(positive regulation of transcription, DNA-templated);GO:0005515(protein binding);GO:0008284(positive regulation of cell proliferation);GO:0004842(ubiquitin-protein transferase activity);GO:0043161(proteasome-mediated ubiquitin-dependent protein catabolic process);GO:0070936(protein K48-linked ubiquitination);GO:0051865(protein autoubiquitination)","NA","NA","NA","ring finger protein 187 [Source:HGNC Symbol;Acc:HGNC:27146]",{"v":11.510649,"d":"11.51"},{"v":10.202881,"d":"10.20"},{"v":1.12817634548516,"d":"1.13"},{"v":0.173992593332659,"d":"0.17"},{"v":0.724070410444277,"d":"0.72"},{"v":0.92663192692119,"d":"0.93"},"up","no"]
[32274,0,"chr11","-",68707440,68751564,"ENST00000255087",10,2579,"ENSG00000132749","TESMIN","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0007275(multicellular organism development);GO:0030154(cell differentiation);GO:0007283(spermatogenesis);GO:0006875(cellular metal ion homeostasis);GO:0010038(response to metal ion)","NA","NA","NA","testis expressed metallothionein like protein [Source:HGNC Symbol;Acc:HGNC:7446]",{"v":0.272966,"d":"0.27"},{"v":0.344484,"d":"0.34"},{"v":0.792390938330953,"d":"0.79"},{"v":-0.335715713019059,"d":"-0.34"},{"v":0.731242651552295,"d":"0.73"},{"v":0.930058975748438,"d":"0.93"},"down","no"]
[56281,0,"chr14","-",69380123,69398627,"ENST00000557016",4,1124,"MSTRG.4502","ERH","GO:0003723(RNA binding);GO:0005515(protein binding);GO:0007049(cell cycle);GO:0006221(pyrimidine nucleotide biosynthetic process);GO:0045747(positive regulation of Notch signaling pathway);GO:0030496(midbody);GO:0006139(nucleobase-containing compound metabolic process);GO:0008327(methyl-CpG binding);GO:0034709(methylosome);GO:0006213(pyrimidine nucleoside metabolic process)","NA","NA","NA","ERH, mRNA splicing and mitosis factor [Source:HGNC Symbol;Acc:HGNC:3447]",{"v":11.050079,"d":"11.05"},{"v":13.40872,"d":"13.41"},{"v":0.824096483482391,"d":"0.82"},{"v":-0.279114839890455,"d":"-0.28"},{"v":0.737281912918574,"d":"0.74"},{"v":0.931598129289254,"d":"0.93"},"down","no"]
[128577,0,"chr22","-",19783224,19854939,"ENST00000329517",8,6706,"ENSG00000185838","GNB1L","GO:0007186(G-protein coupled receptor signaling pathway);GO:0003674(molecular_function);GO:0009898(cytoplasmic side of plasma membrane);GO:0035556(intracellular signal transduction);GO:0035176(social behavior);GO:0005737(cytoplasm)","NA","NA","NA","G protein subunit beta 1 like [Source:HGNC Symbol;Acc:HGNC:4397]",{"v":0.284723,"d":"0.28"},{"v":0.253879,"d":"0.25"},{"v":1.1214909464745,"d":"1.12"},{"v":0.165417973942634,"d":"0.17"},{"v":0.752752914321741,"d":"0.75"},{"v":0.938780954367222,"d":"0.94"},"up","no"]
[72246,0,"chr16","+",31458996,31467164,"ENST00000268314",6,3612,"ENSG00000140691","ARMC5","GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0005925(focal adhesion);GO:0005737(cytoplasm)","NA","NA","NA","armadillo repeat containing 5 [Source:HGNC Symbol;Acc:HGNC:25781]",{"v":0.354208,"d":"0.35"},{"v":0.4276,"d":"0.43"},{"v":0.828362956033676,"d":"0.83"},{"v":-0.271665056468323,"d":"-0.27"},{"v":0.757823297038979,"d":"0.76"},{"v":0.93981808264693,"d":"0.94"},"down","no"]
[136379,0,"chr3","+",49554489,49671545,"ENST00000296452",12,15955,"ENSG00000164061","BSN","GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0005856(cytoskeleton);GO:0030054(cell junction);GO:0045202(synapse);GO:0007416(synapse assembly);GO:0048786(presynaptic active zone);GO:0005634(nucleus);GO:0043005(neuron projection);GO:0007268(chemical synaptic transmission);GO:0030425(dendrite);GO:0060076(excitatory synapse);GO:0035418(protein localization to synapse);GO:0099526(presynapse to nucleus signaling pathway);GO:0009986(cell surface);GO:0014069(postsynaptic density);GO:0030424(axon);GO:0044306(neuron projection terminus);GO:0048788(cytoskeleton of presynaptic active zone);GO:0098793(presynapse);GO:0098831(presynaptic active zone cytoplasmic component)","NA","NA","NA","bassoon presynaptic cytomatrix protein [Source:HGNC Symbol;Acc:HGNC:1117]",{"v":0.084374,"d":"0.08"},{"v":0.0752,"d":"0.08"},{"v":1.12199468085106,"d":"1.12"},{"v":0.1660658364387,"d":"0.17"},{"v":0.764897957594683,"d":"0.76"},{"v":0.942362316230533,"d":"0.94"},"up","no"]
[82410,0,"chr17","+",36211063,36212878,"ENST00000617416",2,1258,"ENSG00000276070","CCL4L2","GO:0005576(extracellular region);GO:0005515(protein binding);GO:0006955(immune response);GO:0005125(cytokine activity);GO:0005615(extracellular space);GO:0008009(chemokine activity);GO:0006935(chemotaxis);GO:0006954(inflammatory response);GO:0007186(G-protein coupled receptor signaling pathway);GO:0048020(CCR chemokine receptor binding);GO:0002548(monocyte chemotaxis);GO:0030593(neutrophil chemotaxis);GO:0043547(positive regulation of GTPase activity);GO:0048247(lymphocyte chemotaxis);GO:0070098(chemokine-mediated signaling pathway);GO:0070374(positive regulation of ERK1 and ERK2 cascade);GO:0071346(cellular response to interferon-gamma);GO:0071347(cellular response to interleukin-1);GO:0071356(cellular response to tumor necrosis factor)","04064(NF-kappa B signaling pathway);04060(Cytokine-cytokine receptor interaction);04620(Toll-like receptor signaling pathway);04623(Cytosolic DNA-sensing pathway);04062(Chemokine signaling pathway);05132(Salmonella infection)","K12964","NA","C-C motif chemokine ligand 4 like 2 [Source:HGNC Symbol;Acc:HGNC:24066]",{"v":1.174011,"d":"1.17"},{"v":1.056604,"d":"1.06"},{"v":1.11111731547486,"d":"1.11"},{"v":0.15201114932689,"d":"0.15"},{"v":0.770775452605386,"d":"0.77"},{"v":0.944244014884426,"d":"0.94"},"up","no"]
[156820,0,"chr5","+",95555137,95603680,"ENST00000513814",9,1958,"ENSG00000164291","ARSK","GO:0046872(metal ion binding);GO:0016787(hydrolase activity);GO:0003824(catalytic activity);GO:0008152(metabolic process);GO:0005576(extracellular region);GO:0008484(sulfuric ester hydrolase activity);GO:0006687(glycosphingolipid metabolic process);GO:0043687(post-translational protein modification);GO:0005788(endoplasmic reticulum lumen);GO:0004065(arylsulfatase activity)","NA","NA","NA","arylsulfatase family member K [Source:HGNC Symbol;Acc:HGNC:25239]",{"v":0.320429,"d":"0.32"},{"v":0.388839,"d":"0.39"},{"v":0.824066001609921,"d":"0.82"},{"v":-0.279168203617213,"d":"-0.28"},{"v":0.776539458035541,"d":"0.78"},{"v":0.945717573352997,"d":"0.95"},"down","no"]
[22864,0,"chr10","-",100526049,100529862,"ENST00000466088",4,829,"MSTRG.1916","NDUFB8","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0055114(oxidation-reduction process);GO:0005739(mitochondrion);GO:0005743(mitochondrial inner membrane);GO:0005747(mitochondrial respiratory chain complex I);GO:0006120(mitochondrial electron transport, NADH to ubiquinone);GO:0070469(respiratory chain);GO:0008137(NADH dehydrogenase (ubiquinone) activity);GO:0003954(NADH dehydrogenase activity);GO:0032981(mitochondrial respiratory chain complex I assembly);GO:0005783(endoplasmic reticulum)","00190(Oxidative phosphorylation);04723(Retrograde endocannabinoid signaling);05010(Alzheimer's disease);05012(Parkinson's disease);05016(Huntington's disease);04932(Non-alcoholic fatty liver disease (NAFLD))","NA","NA","NADH:ubiquinone oxidoreductase subunit B8 [Source:HGNC Symbol;Acc:HGNC:7703]",{"v":2.481391,"d":"2.48"},{"v":2.266572,"d":"2.27"},{"v":1.09477704657077,"d":"1.09"},{"v":0.130637092148656,"d":"0.13"},{"v":0.782219955575639,"d":"0.78"},{"v":0.94668574295014,"d":"0.95"},"up","no"]
[139479,0,"chr3","+",119579590,119588007,"ENST00000478927",4,1501,"ENSG00000144843","ADPRH","GO:0000287(magnesium ion binding);GO:0016787(hydrolase activity);GO:0005515(protein binding);GO:0005622(intracellular);GO:0006464(cellular protein modification process);GO:0030955(potassium ion binding);GO:0003875(ADP-ribosylarginine hydrolase activity);GO:0051725(protein de-ADP-ribosylation)","NA","NA","NA","ADP-ribosylarginine hydrolase [Source:HGNC Symbol;Acc:HGNC:269]",{"v":0.811353,"d":"0.81"},{"v":0.967045,"d":"0.97"},{"v":0.839002321505204,"d":"0.84"},{"v":-0.253253292304014,"d":"-0.25"},{"v":0.788574036316293,"d":"0.79"},{"v":0.948918758958003,"d":"0.95"},"down","no"]
[160158,0,"chr5","-",151101105,151157882,"ENST00000354546",26,2593,"MSTRG.12467","ANXA6","GO:0005509(calcium ion binding);GO:0005544(calcium-dependent phospholipid binding);GO:0005739(mitochondrion);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005765(lysosomal membrane);GO:0005525(GTP binding);GO:0042803(protein homodimerization activity);GO:0042470(melanosome);GO:0005925(focal adhesion);GO:0008289(lipid binding);GO:0005515(protein binding);GO:0006816(calcium ion transport);GO:0006937(regulation of muscle contraction);GO:0051560(mitochondrial calcium ion homeostasis);GO:0097190(apoptotic signaling pathway);GO:0048471(perinuclear region of cytoplasm);GO:0031902(late endosome membrane);GO:0070062(extracellular exosome);GO:0034220(ion transmembrane transport);GO:0015485(cholesterol binding);GO:0051260(protein homooligomerization);GO:0048306(calcium-dependent protein binding);GO:0015276(ligand-gated ion channel activity)","NA","NA","NA","annexin A6 [Source:HGNC Symbol;Acc:HGNC:544]",{"v":107.672768,"d":"107.67"},{"v":99.601204,"d":"99.60"},{"v":1.0810388195709,"d":"1.08"},{"v":0.11241833047021,"d":"0.11"},{"v":0.794945926186299,"d":"0.79"},{"v":0.950542342629659,"d":"0.95"},"up","no"]
[7878,0,"chr1","+",89524854,89597848,"ENST00000640258",9,8034,"MSTRG.696","LRRC8B","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0006810(transport);GO:0005737(cytoplasm);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0006811(ion transport);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0007165(signal transduction);GO:0055085(transmembrane transport);GO:0005225(volume-sensitive anion channel activity);GO:0044070(regulation of anion transport);GO:0034702(ion channel complex);GO:0098656(anion transmembrane transport)","NA","NA","NA","leucine rich repeat containing 8 family member B [Source:HGNC Symbol;Acc:HGNC:30692]",{"v":0.3231,"d":"0.32"},{"v":0.376811,"d":"0.38"},{"v":0.857459044454647,"d":"0.86"},{"v":-0.221860330626112,"d":"-0.22"},{"v":0.808791913962601,"d":"0.81"},{"v":0.95538110403942,"d":"0.96"},"down","no"]
[23031,0,"chr10","-",101786563,101791453,"ENST00000461645",3,743,"MSTRG.1926","MGEA5","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005829(cytosol);GO:0016787(hydrolase activity);GO:0008152(metabolic process);GO:0016798(hydrolase activity, acting on glycosyl bonds);GO:0004415(hyalurononglucosaminidase activity);GO:0016231(beta-N-acetylglucosaminidase activity);GO:0102166([protein]-3-O-(N-acetyl-D-glucosaminyl)-L-threonine O-N-acetyl-alpha-D-glucosaminase activity);GO:0102167([protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine O-N-acetyl-alpha-D-glucosaminase activity);GO:0102571([protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine/L-threonine O-N-acetyl-alpha-D-glucosaminase activity);GO:0006044(N-acetylglucosamine metabolic process);GO:0006493(protein O-linked glycosylation);GO:0006516(glycoprotein catabolic process);GO:0006517(protein deglycosylation)","04931(Insulin resistance)","NA","NA","meningioma expressed antigen 5 (hyaluronidase) [Source:HGNC Symbol;Acc:HGNC:7056]",{"v":6.099617,"d":"6.10"},{"v":7.071644,"d":"7.07"},{"v":0.862545823856518,"d":"0.86"},{"v":-0.213326991043181,"d":"-0.21"},{"v":0.816268691104808,"d":"0.82"},{"v":0.957405212387621,"d":"0.96"},"down","no"]
[165697,0,"chr6","+",37005658,37012033,"ENST00000459781",4,866,"MSTRG.13002","FGD2","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0046872(metal ion binding);GO:0005794(Golgi apparatus);GO:0005886(plasma membrane);GO:0005089(Rho guanyl-nucleotide exchange factor activity);GO:0035023(regulation of Rho protein signal transduction);GO:0043547(positive regulation of GTPase activity);GO:0005856(cytoskeleton);GO:0042995(cell projection);GO:0005515(protein binding);GO:0005085(guanyl-nucleotide exchange factor activity);GO:0005768(endosome);GO:0005829(cytosol);GO:0030027(lamellipodium);GO:0051056(regulation of small GTPase mediated signal transduction);GO:0032587(ruffle membrane);GO:0005769(early endosome);GO:0007010(cytoskeleton organization);GO:0031901(early endosome membrane);GO:0008360(regulation of cell shape);GO:0001726(ruffle);GO:0030036(actin cytoskeleton organization);GO:0043087(regulation of GTPase activity);GO:0043065(positive regulation of apoptotic process);GO:0046847(filopodium assembly);GO:0031267(small GTPase binding);GO:1901981(phosphatidylinositol phosphate binding);GO:0043507(positive regulation of JUN kinase activity)","NA","NA","NA","FYVE, RhoGEF and PH domain containing 2 [Source:HGNC Symbol;Acc:HGNC:3664]",{"v":1.189805,"d":"1.19"},{"v":1.112384,"d":"1.11"},{"v":1.06959916719406,"d":"1.07"},{"v":0.0970702472403656,"d":"0.10"},{"v":0.820929431843766,"d":"0.82"},{"v":0.958254881552638,"d":"0.96"},"up","no"]
[78025,0,"chr17","-",4630902,4642294,"ENST00000570836",15,2784,"ENSG00000161905","ALOX15","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0046872(metal ion binding);GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0006629(lipid metabolic process);GO:0005829(cytosol);GO:0006631(fatty acid metabolic process);GO:0005886(plasma membrane);GO:0005506(iron ion binding);GO:0006646(phosphatidylethanolamine biosynthetic process);GO:0051213(dioxygenase activity);GO:0008289(lipid binding);GO:0016702(oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen);GO:0005515(protein binding);GO:0031234(extrinsic component of cytoplasmic side of plasma membrane);GO:0030282(bone mineralization);GO:0005546(phosphatidylinositol-4,5-bisphosphate binding);GO:0001503(ossification);GO:0006954(inflammatory response);GO:0070374(positive regulation of ERK1 and ERK2 cascade);GO:0034976(response to endoplasmic reticulum stress);GO:0005811(lipid particle);GO:0043277(apoptotic cell clearance);GO:0030838(positive regulation of actin filament polymerization);GO:0042060(wound healing);GO:0050473(arachidonate 15-lipoxygenase activity);GO:0019369(arachidonic acid metabolic process);GO:0019372(lipoxygenase pathway);GO:0051122(hepoxilin biosynthetic process);GO:0071277(cellular response to calcium ion);GO:0004052(arachidonate 12-lipoxygenase activity);GO:0010811(positive regulation of cell-substrate adhesion);GO:0006691(leukotriene metabolic process);GO:0002820(negative regulation of adaptive immune response);GO:0047977(hepoxilin-epoxide hydrolase activity);GO:0051120(hepoxilin A3 synthase activity);GO:0097260(eoxin A4 synthase activity);GO:0034116(positive regulation of heterotypic cell-cell adhesion);GO:0035358(regulation of peroxisome proliferator activated receptor signaling pathway);GO:0035963(cellular response to interleukin-13);GO:1901074(regulation of engulfment of apoptotic cell);GO:2001303(lipoxin A4 biosynthetic process)","00590(Arachidonic acid metabolism);00591(Linoleic acid metabolism);04216(Ferroptosis);04217(Necroptosis);04726(Serotonergic synapse)","NA","NA","arachidonate 15-lipoxygenase [Source:HGNC Symbol;Acc:HGNC:433]",{"v":0.79331,"d":"0.79"},{"v":0.915032,"d":"0.92"},{"v":0.866975144038678,"d":"0.87"},{"v":-0.205937462554638,"d":"-0.21"},{"v":0.82634850624359,"d":"0.83"},{"v":0.959531401329995,"d":"0.96"},"down","no"]
[158207,0,"chr5","-",132483085,132489032,"ENST00000472045",2,5153,"MSTRG.12289","IRF1","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0006915(apoptotic process);GO:0005515(protein binding);GO:0008285(negative regulation of cell proliferation);GO:0045893(positive regulation of transcription, DNA-templated);GO:0002376(immune system process);GO:0045087(innate immune response);GO:0000975(regulatory region DNA binding);GO:0051607(defense response to virus);GO:0050776(regulation of immune response);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0007050(cell cycle arrest);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0071260(cellular response to mechanical stimulus);GO:0045892(negative regulation of transcription, DNA-templated);GO:0000790(nuclear chromatin);GO:0006366(transcription from RNA polymerase II promoter);GO:0051726(regulation of cell cycle);GO:0032728(positive regulation of interferon-beta production);GO:0060333(interferon-gamma-mediated signaling pathway);GO:0001077(transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0060337(type I interferon signaling pathway);GO:0007596(blood coagulation);GO:0035458(cellular response to interferon-beta);GO:0045088(regulation of innate immune response);GO:0043565(sequence-specific DNA binding);GO:0002819(regulation of adaptive immune response);GO:0010468(regulation of gene expression);GO:0032481(positive regulation of type I interferon production);GO:0034124(regulation of MyD88-dependent toll-like receptor signaling pathway);GO:0043374(CD8-positive, alpha-beta T cell differentiation);GO:0045084(positive regulation of interleukin-12 biosynthetic process);GO:0045590(negative regulation of regulatory T cell differentiation);GO:2000564(regulation of CD8-positive, alpha-beta T cell proliferation)","04917(Prolactin signaling pathway);05133(Pertussis);05160(Hepatitis C);05165(Human papillomavirus infection)","NA","NA","interferon regulatory factor 1 [Source:HGNC Symbol;Acc:HGNC:6116]",{"v":0.609616,"d":"0.61"},{"v":0.700475,"d":"0.70"},{"v":0.870289446447054,"d":"0.87"},{"v":-0.200432793345699,"d":"-0.20"},{"v":0.833593643534526,"d":"0.83"},{"v":0.96150982622841,"d":"0.96"},"down","no"]
[35441,0,"chr11","-",116773799,116788050,"ENST00000227322",14,6566,"ENSG00000109917","ZPR1","GO:0006397(mRNA processing);GO:0008380(RNA splicing);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0042995(cell projection);GO:0048471(perinuclear region of cytoplasm);GO:0030154(cell differentiation);GO:0005654(nucleoplasm);GO:0005730(nucleolus);GO:0005515(protein binding);GO:0030424(axon);GO:0030426(growth cone);GO:0043204(perikaryon);GO:0010628(positive regulation of gene expression);GO:0042307(positive regulation of protein import into nucleus);GO:0007165(signal transduction);GO:0000226(microtubule cytoskeleton organization);GO:0008283(cell proliferation);GO:0021510(spinal cord development);GO:0031369(translation initiation factor binding);GO:0032797(SMN complex);GO:0097504(Gemini of coiled bodies);GO:0015030(Cajal body);GO:0043025(neuronal cell body);GO:0071364(cellular response to epidermal growth factor stimulus);GO:0030971(receptor tyrosine kinase binding);GO:0001833(inner cell mass cell proliferation);GO:0001834(trophectodermal cell proliferation);GO:0030576(Cajal body organization);GO:0031641(regulation of myelination);GO:0033120(positive regulation of RNA splicing);GO:0042023(DNA endoreduplication);GO:0045927(positive regulation of growth);GO:0061564(axon development);GO:0071931(positive regulation of transcription involved in G1/S transition of mitotic cell cycle);GO:1902742(apoptotic process involved in development);GO:1990261(pre-mRNA catabolic process);GO:2000672(negative regulation of motor neuron apoptotic process)","NA","NA","NA","ZPR1 zinc finger [Source:HGNC Symbol;Acc:HGNC:13051]",{"v":2.622477,"d":"2.62"},{"v":2.485016,"d":"2.49"},{"v":1.05531594162774,"d":"1.06"},{"v":0.0776749792004054,"d":"0.08"},{"v":0.838386987529932,"d":"0.84"},{"v":0.962397894049881,"d":"0.96"},"up","no"]
[93113,0,"chr18","+",62523007,62578583,"ENST00000269499",14,5959,"ENSG00000141664","ZCCHC2","GO:0003676(nucleic acid binding);GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0035091(phosphatidylinositol binding);GO:0005737(cytoplasm)","NA","NA","NA","zinc finger CCHC-type containing 2 [Source:HGNC Symbol;Acc:HGNC:22916]",{"v":2.064015,"d":"2.06"},{"v":2.350742,"d":"2.35"},{"v":0.878027022957007,"d":"0.88"},{"v":-0.187662752750732,"d":"-0.19"},{"v":0.844870080975843,"d":"0.84"},{"v":0.964709121879181,"d":"0.96"},"down","no"]
[50738,0,"chr13","+",60397293,60573878,"ENST00000535286",14,2579,"ENSG00000083544","TDRD3","GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016569(covalent chromatin modification);GO:1903506(regulation of nucleic acid-templated transcription);GO:0003713(transcription coactivator activity);GO:0005515(protein binding);GO:0003682(chromatin binding);GO:0035145(exon-exon junction complex);GO:0035064(methylated histone binding)","NA","NA","NA","tudor domain containing 3 [Source:HGNC Symbol;Acc:HGNC:20612]",{"v":1.117035,"d":"1.12"},{"v":1.274611,"d":"1.27"},{"v":0.876373262116834,"d":"0.88"},{"v":-0.190382626077131,"d":"-0.19"},{"v":0.851963003389939,"d":"0.85"},{"v":0.966825142683792,"d":"0.97"},"down","no"]
[122177,0,"chr20","-",17613678,17682233,"ENST00000377813",25,5041,"ENSG00000125844","RRBP1","GO:0005783(endoplasmic reticulum);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0015031(protein transport);GO:0030176(integral component of endoplasmic reticulum membrane);GO:0003723(RNA binding);GO:0006810(transport);GO:0005789(endoplasmic reticulum membrane);GO:0004872(receptor activity);GO:0006412(translation);GO:0001649(osteoblast differentiation);GO:0005840(ribosome)","04141(Protein processing in endoplasmic reticulum)","NA","NA","ribosome binding protein 1 [Source:HGNC Symbol;Acc:HGNC:10448]",{"v":2.703791,"d":"2.70"},{"v":3.045488,"d":"3.05"},{"v":0.88780221757564,"d":"0.89"},{"v":-0.171689782618383,"d":"-0.17"},{"v":0.863938135044954,"d":"0.86"},{"v":0.969118612740054,"d":"0.97"},"down","no"]
[97128,0,"chr19","-",12730640,12734775,"ENST00000242784",3,970,"MSTRG.7842","TRIR","GO:0005515(protein binding)","NA","NA","NA","telomerase RNA component interacting RNase [Source:HGNC Symbol;Acc:HGNC:28424]",{"v":100.951233,"d":"100.95"},{"v":97.552147,"d":"97.55"},{"v":1.03484378462731,"d":"1.03"},{"v":0.0494130013930663,"d":"0.05"},{"v":0.870249342234611,"d":"0.87"},{"v":0.970968563356593,"d":"0.97"},"up","no"]
[151459,0,"chr4","+",151099624,151104637,"ENST00000509736",4,576,"MSTRG.11861","RPS3A","GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0006412(translation);GO:0006413(translational initiation);GO:0005783(endoplasmic reticulum);GO:0005730(nucleolus);GO:0005829(cytosol);GO:0030529(intracellular ribonucleoprotein complex);GO:0005622(intracellular);GO:0003735(structural constituent of ribosome);GO:0005840(ribosome);GO:0005515(protein binding);GO:0022627(cytosolic small ribosomal subunit);GO:0030154(cell differentiation);GO:0005925(focal adhesion);GO:0005654(nucleoplasm);GO:0070062(extracellular exosome);GO:0031012(extracellular matrix);GO:0002181(cytoplasmic translation);GO:0043066(negative regulation of apoptotic process);GO:0006364(rRNA processing);GO:0000184(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay);GO:0019083(viral transcription);GO:0048027(mRNA 5'-UTR binding);GO:0006614(SRP-dependent cotranslational protein targeting to membrane)","03010(Ribosome)","NA","NA","ribosomal protein S3A [Source:HGNC Symbol;Acc:HGNC:10421]",{"v":1.979762,"d":"1.98"},{"v":1.863952,"d":"1.86"},{"v":1.06213142827712,"d":"1.06"},{"v":0.0869622964546035,"d":"0.09"},{"v":0.873181854700356,"d":"0.87"},{"v":0.971096460412019,"d":"0.97"},"up","no"]
[123093,0,"chr20","-",34560542,34677085,"ENST00000217446",12,1632,"MSTRG.9679","PIGU","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0006506(GPI anchor biosynthetic process);GO:0016255(attachment of GPI anchor to protein);GO:0042765(GPI-anchor transamidase complex);GO:0005886(plasma membrane);GO:0030176(integral component of endoplasmic reticulum membrane);GO:0003923(GPI-anchor transamidase activity);GO:0034235(GPI anchor binding);GO:0046425(regulation of JAK-STAT cascade)","00563(Glycosylphosphatidylinositol(GPI)-anchor biosynthesis)","K05293","NA","phosphatidylinositol glycan anchor biosynthesis class U [Source:HGNC Symbol;Acc:HGNC:15791]",{"v":2.985924,"d":"2.99"},{"v":2.899118,"d":"2.90"},{"v":1.02994221001008,"d":"1.03"},{"v":0.042563390155227,"d":"0.04"},{"v":0.882049288965918,"d":"0.88"},{"v":0.973450187117804,"d":"0.97"},"up","no"]
[94267,0,"chr19","+",1356290,1371479,"ENST00000591433",12,2603,"ENSG00000160953","MUM1","GO:0005634(nucleus);GO:0006281(DNA repair);GO:0006325(chromatin organization);GO:0031491(nucleosome binding);GO:0005829(cytosol);GO:0006974(cellular response to DNA damage stimulus);GO:0005515(protein binding)","NA","NA","NA","melanoma associated antigen (mutated) 1 [Source:HGNC Symbol;Acc:HGNC:29641]",{"v":0.275344,"d":"0.28"},{"v":0.265707,"d":"0.27"},{"v":1.03626927404999,"d":"1.04"},{"v":0.051398935320774,"d":"0.05"},{"v":0.889010217654243,"d":"0.89"},{"v":0.975245725713702,"d":"0.98"},"up","no"]
[183181,0,"chr8","+",38901291,38973909,"ENST00000617275",12,5582,"MSTRG.14300","PLEKHA2","GO:0030165(PDZ domain binding);GO:0043325(phosphatidylinositol-3,4-bisphosphate binding)","NA","NA","NA","pleckstrin homology domain containing A2 [Source:HGNC Symbol;Acc:HGNC:14336]",{"v":5.361163,"d":"5.36"},{"v":5.247647,"d":"5.25"},{"v":1.02163179040054,"d":"1.02"},{"v":0.0308753235945571,"d":"0.03"},{"v":0.893680270901829,"d":"0.89"},{"v":0.975410742618925,"d":"0.98"},"up","no"]
[165275,0,"chr6","+",33411126,33416051,"ENST00000495509",15,1752,"MSTRG.12952","PHF1","GO:0046872(metal ion binding);GO:0006974(cellular response to DNA damage stimulus);GO:0035064(methylated histone binding);GO:0031060(regulation of histone methylation);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005654(nucleoplasm);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0016569(covalent chromatin modification);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0005813(centrosome);GO:0005815(microtubule organizing center);GO:0035098(ESC/E(Z) complex);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0061087(positive regulation of histone H3-K27 methylation);GO:0045814(negative regulation of gene expression, epigenetic);GO:0061086(negative regulation of histone H3-K27 methylation);GO:0035861(site of double-strand break);GO:0003682(chromatin binding)","NA","NA","NA","PHD finger protein 1 [Source:HGNC Symbol;Acc:HGNC:8919]",{"v":6.92724,"d":"6.93"},{"v":7.612043,"d":"7.61"},{"v":0.910036898110008,"d":"0.91"},{"v":-0.136003053267092,"d":"-0.14"},{"v":0.906455242335466,"d":"0.91"},{"v":0.978483661825882,"d":"0.98"},"down","no"]
[82678,0,"chr17","+",38724256,38727192,"ENST00000615741",1,2937,"MSTRG.6755","MLLT6","GO:0046872(metal ion binding);GO:0005515(protein binding);GO:0003014(renal system process);GO:0007588(excretion);GO:0010765(positive regulation of sodium ion transport);GO:0035811(negative regulation of urine volume);GO:0035812(renal sodium excretion);GO:0036359(renal potassium excretion);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:2001161(negative regulation of histone H3-K79 methylation)","NA","NA","NA","MLLT6, PHD finger containing [Source:HGNC Symbol;Acc:HGNC:7138]",{"v":0.322544,"d":"0.32"},{"v":0.312542,"d":"0.31"},{"v":1.03200209891791,"d":"1.03"},{"v":0.0454459049621111,"d":"0.05"},{"v":0.914571257453303,"d":"0.91"},{"v":0.981625396088344,"d":"0.98"},"up","no"]
[147633,0,"chr4","-",56647998,56656525,"ENST00000556614",3,1138,"MSTRG.11637","HOPX","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0007275(multicellular organism development);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0051131(chaperone-mediated protein complex assembly);GO:0001829(trophectodermal cell differentiation);GO:0045596(negative regulation of cell differentiation)","NA","NA","NA","HOP homeobox [Source:HGNC Symbol;Acc:HGNC:24961]",{"v":2.5721,"d":"2.57"},{"v":2.542905,"d":"2.54"},{"v":1.01148096370096,"d":"1.01"},{"v":0.0164691683068236,"d":"0.02"},{"v":0.921315145546558,"d":"0.92"},{"v":0.98384134513367,"d":"0.98"},"up","no"]
[31985,0,"chr11","+",67432776,67434644,"ENST00000526268",7,787,"MSTRG.2611","RPS6KB2","GO:0004672(protein kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0000166(nucleotide binding);GO:0004674(protein serine/threonine kinase activity);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0007165(signal transduction);GO:0045948(positive regulation of translational initiation);GO:0035556(intracellular signal transduction);GO:0005654(nucleoplasm);GO:0006412(translation);GO:0004711(ribosomal protein S6 kinase activity);GO:0042277(peptide binding);GO:0043491(protein kinase B signaling)","04012(ErbB signaling pathway);04350(TGF-beta signaling pathway);04371(Apelin signaling pathway);04066(HIF-1 signaling pathway);04151(PI3K-Akt signaling pathway);04152(AMPK signaling pathway);04150(mTOR signaling pathway);04140(Autophagy - animal);04666(Fc gamma R-mediated phagocytosis);04910(Insulin signaling pathway);04211(Longevity regulating pathway - mammal);04213(Longevity regulating pathway - multiple species);05200(Pathways in cancer);05231(Choline metabolism in cancer);05205(Proteoglycans in cancer);05212(Pancreatic cancer);05225(Hepatocellular carcinoma);05226(Gastric cancer);05221(Acute myeloid leukemia);05224(Breast cancer);04931(Insulin resistance);05165(Human papillomavirus infection);01521(EGFR tyrosine kinase inhibitor resistance);01522(Endocrine resistance)","NA","NA","ribosomal protein S6 kinase B2 [Source:HGNC Symbol;Acc:HGNC:10437]",{"v":1.052851,"d":"1.05"},{"v":1.028853,"d":"1.03"},{"v":1.02332500366913,"d":"1.02"},{"v":0.0332644116682979,"d":"0.03"},{"v":0.927518852838791,"d":"0.93"},{"v":0.985451918638984,"d":"0.99"},"up","no"]
[171647,0,"chr7","-",6161776,6272644,"ENST00000350796",13,4505,"ENSG00000008256","CYTH3","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0005886(plasma membrane);GO:0043547(positive regulation of GTPase activity);GO:0005515(protein binding);GO:0005086(ARF guanyl-nucleotide exchange factor activity);GO:0032012(regulation of ARF protein signal transduction);GO:0005085(guanyl-nucleotide exchange factor activity);GO:0008289(lipid binding);GO:0031234(extrinsic component of cytoplasmic side of plasma membrane);GO:0005547(phosphatidylinositol-3,4,5-trisphosphate binding);GO:0000139(Golgi membrane);GO:0045785(positive regulation of cell adhesion);GO:0048193(Golgi vesicle transport);GO:0090162(establishment of epithelial cell polarity);GO:0001726(ruffle)","04072(Phospholipase D signaling pathway);04144(Endocytosis)","K18441","NA","cytohesin 3 [Source:HGNC Symbol;Acc:HGNC:9504]",{"v":1.716112,"d":"1.72"},{"v":1.857242,"d":"1.86"},{"v":0.924010979721544,"d":"0.92"},{"v":-0.114018100068856,"d":"-0.11"},{"v":0.934321673901712,"d":"0.93"},{"v":0.987314230493759,"d":"0.99"},"down","no"]
[18187,0,"chr10","+",5684838,5763740,"ENST00000328090",21,8626,"MSTRG.1523","FAM208B","GO:0005515(protein binding)","NA","NA","NA","family with sequence similarity 208 member B [Source:HGNC Symbol;Acc:HGNC:23484]",{"v":2.661635,"d":"2.66"},{"v":2.675483,"d":"2.68"},{"v":0.994824112132277,"d":"0.99"},{"v":-0.00748661946755718,"d":"-0.01"},{"v":0.940175828652926,"d":"0.94"},{"v":0.988490525345437,"d":"0.99"},"down","no"]
[29323,0,"chr11","-",57551656,57568284,"ENST00000340573",4,1573,"MSTRG.2393","UBE2L6","GO:0016740(transferase activity);GO:0016567(protein ubiquitination);GO:0005515(protein binding);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0044267(cellular protein metabolic process);GO:0004842(ubiquitin-protein transferase activity);GO:0006464(cellular protein modification process);GO:0043130(ubiquitin binding);GO:0019985(translesion synthesis);GO:0032480(negative regulation of type I interferon production);GO:0019787(ubiquitin-like protein transferase activity);GO:0042296(ISG15 transferase activity);GO:0019941(modification-dependent protein catabolic process);GO:0032020(ISG15-protein conjugation);GO:0000166(nucleotide binding);GO:0005524(ATP binding)","04120(Ubiquitin mediated proteolysis);05012(Parkinson's disease)","K04553","EC:2.3.2.23","ubiquitin conjugating enzyme E2 L6 [Source:HGNC Symbol;Acc:HGNC:12490]",{"v":0.705597,"d":"0.71"},{"v":0.762265,"d":"0.76"},{"v":0.925658399637921,"d":"0.93"},{"v":-0.111448208175092,"d":"-0.11"},{"v":0.947637294568961,"d":"0.95"},{"v":0.990341470405209,"d":"0.99"},"down","no"]
[158082,0,"chr5","-",131423921,131635236,"ENST00000509018",28,8357,"MSTRG.12281","RAPGEF6","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0007264(small GTPase mediated signal transduction);GO:0005829(cytosol);GO:0007165(signal transduction);GO:0005813(centrosome);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0005085(guanyl-nucleotide exchange factor activity);GO:0007265(Ras protein signal transduction);GO:0043547(positive regulation of GTPase activity);GO:0016324(apical plasma membrane);GO:0043087(regulation of GTPase activity);GO:0030033(microvillus assembly);GO:0030742(GTP-dependent protein binding);GO:0030139(endocytic vesicle);GO:0070300(phosphatidic acid binding);GO:0072659(protein localization to plasma membrane);GO:0017016(Ras GTPase binding);GO:0005622(intracellular)","04015(Rap1 signaling pathway);04530(Tight junction)","K08020","NA","Rap guanine nucleotide exchange factor 6 [Source:HGNC Symbol;Acc:HGNC:20655]",{"v":4.877284,"d":"4.88"},{"v":5.215839,"d":"5.22"},{"v":0.935090979610375,"d":"0.94"},{"v":-0.0968213561467248,"d":"-0.10"},{"v":0.952548916974566,"d":"0.95"},{"v":0.991322081312771,"d":"0.99"},"down","no"]
[3272,0,"chr1","-",27404226,27490158,"ENST00000618852",9,5676,"MSTRG.296","WASF2","GO:0005737(cytoplasm);GO:0003779(actin binding);GO:0030036(actin cytoskeleton organization);GO:0005856(cytoskeleton);GO:0042995(cell projection);GO:0005515(protein binding);GO:0038096(Fc-gamma receptor signaling pathway involved in phagocytosis);GO:0005829(cytosol);GO:0045296(cadherin binding);GO:0030027(lamellipodium);GO:0070062(extracellular exosome);GO:0016032(viral process);GO:0017124(SH3 domain binding);GO:0015629(actin cytoskeleton);GO:0048010(vascular endothelial growth factor receptor signaling pathway);GO:0032403(protein complex binding);GO:0010592(positive regulation of lamellipodium assembly);GO:0007188(adenylate cyclase-modulating G-protein coupled receptor signaling pathway);GO:0051497(negative regulation of stress fiber assembly);GO:0031209(SCAR complex);GO:0005622(intracellular);GO:0001525(angiogenesis);GO:0001667(ameboidal-type cell migration);GO:0006897(endocytosis);GO:0016601(Rac protein signal transduction);GO:0030032(lamellipodium assembly);GO:0030048(actin filament-based movement);GO:0035855(megakaryocyte development);GO:0072673(lamellipodium morphogenesis);GO:0001726(ruffle);GO:0005769(early endosome);GO:0005911(cell-cell junction)","04520(Adherens junction);04810(Regulation of actin cytoskeleton);04666(Fc gamma R-mediated phagocytosis);05231(Choline metabolism in cancer);05132(Salmonella infection);05131(Shigellosis);05100(Bacterial invasion of epithelial cells)","K05748","NA","WAS protein family member 2 [Source:HGNC Symbol;Acc:HGNC:12733]",{"v":71.9161,"d":"71.92"},{"v":73.503189,"d":"73.50"},{"v":0.978407889214167,"d":"0.98"},{"v":-0.0314920580659424,"d":"-0.03"},{"v":0.9682576850754,"d":"0.97"},{"v":0.997000842864805,"d":"1.00"},"down","no"]
[78624,0,"chr17","-",7225341,7234545,"ENST00000005340",15,3018,"MSTRG.6392","DVL2","GO:0051091(positive regulation of sequence-specific DNA binding transcription factor activity);GO:0005737(cytoplasm);GO:0001934(positive regulation of protein phosphorylation);GO:0003151(outflow tract morphogenesis);GO:0043507(positive regulation of JUN kinase activity);GO:0005634(nucleus);GO:0016020(membrane);GO:0005654(nucleoplasm);GO:0035556(intracellular signal transduction);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0016235(aggresome);GO:0016604(nuclear body);GO:0007275(multicellular organism development);GO:0016055(Wnt signaling pathway);GO:0031410(cytoplasmic vesicle);GO:0042802(identical protein binding);GO:0006366(transcription from RNA polymerase II promoter);GO:0061024(membrane organization);GO:0060071(Wnt signaling pathway, planar cell polarity pathway);GO:0090090(negative regulation of canonical Wnt signaling pathway);GO:0045893(positive regulation of transcription, DNA-templated);GO:0060070(canonical Wnt signaling pathway);GO:0005109(frizzled binding);GO:0090179(planar cell polarity pathway involved in neural tube closure);GO:1904886(beta-catenin destruction complex disassembly);GO:0019901(protein kinase binding);GO:0019904(protein domain specific binding);GO:0030674(protein binding, bridging);GO:0043621(protein self-association);GO:0048365(Rac GTPase binding);GO:0001843(neural tube closure);GO:0003007(heart morphogenesis);GO:0007379(segment specification);GO:0007507(heart development);GO:0022007(convergent extension involved in neural plate elongation);GO:0034613(cellular protein localization);GO:0035282(segmentation);GO:0035329(hippo signaling);GO:0035567(non-canonical Wnt signaling pathway);GO:0043547(positive regulation of GTPase activity);GO:0044340(canonical Wnt signaling pathway involved in regulation of cell proliferation);GO:0051259(protein oligomerization);GO:0060029(convergent extension involved in organogenesis);GO:0061098(positive regulation of protein tyrosine kinase activity);GO:0090103(cochlea morphogenesis);GO:0090263(positive regulation of canonical Wnt signaling pathway);GO:0016328(lateral plasma membrane);GO:0030136(clathrin-coated vesicle);GO:0045177(apical part of cell);GO:0045334(clathrin-coated endocytic vesicle);GO:0005622(intracellular)","04310(Wnt signaling pathway);04330(Notch signaling pathway);04390(Hippo signaling pathway);04150(mTOR signaling pathway);04550(Signaling pathways regulating pluripotency of stem cells);04916(Melanogenesis);05200(Pathways in cancer);05225(Hepatocellular carcinoma);05226(Gastric cancer);05217(Basal cell carcinoma);05224(Breast cancer);05166(HTLV-I infection);05165(Human papillomavirus infection)","K02353","NA","dishevelled segment polarity protein 2 [Source:HGNC Symbol;Acc:HGNC:3086]",{"v":1.677214,"d":"1.68"},{"v":1.718396,"d":"1.72"},{"v":0.976034627641126,"d":"0.98"},{"v":-0.0349957624271384,"d":"-0.03"},{"v":0.975330316371446,"d":"0.98"},{"v":0.998504204950932,"d":"1.00"},"down","no"]
[166237,0,"chr6","+",43477573,43506553,"ENST00000372452",10,2665,"ENSG00000137221","TJAP1","GO:0005923(bicellular tight junction);GO:0005794(Golgi apparatus);GO:0030054(cell junction);GO:0005515(protein binding);GO:0007030(Golgi organization);GO:0005737(cytoplasm);GO:0005768(endosome);GO:0005802(trans-Golgi network);GO:0005886(plasma membrane)","04530(Tight junction)","K06105","NA","tight junction associated protein 1 [Source:HGNC Symbol;Acc:HGNC:17949]",{"v":1.567216,"d":"1.57"},{"v":1.659526,"d":"1.66"},{"v":0.944375683177004,"d":"0.94"},{"v":-0.0825672009400413,"d":"-0.08"},{"v":0.980449703049938,"d":"0.98"},{"v":0.999266010131746,"d":"1.00"},"down","no"]
[45572,0,"chr12","+",98593660,98601708,"ENST00000552981",8,1351,"MSTRG.3629","SLC25A3","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005739(mitochondrion);GO:0005743(mitochondrial inner membrane);GO:0015293(symporter activity);GO:0055085(transmembrane transport);GO:0070062(extracellular exosome);GO:0035435(phosphate ion transmembrane transport);GO:0005887(integral component of plasma membrane);GO:0006839(mitochondrial transport);GO:0032403(protein complex binding);GO:0015320(phosphate ion carrier activity);GO:0043209(myelin sheath)","NA","NA","NA","solute carrier family 25 member 3 [Source:HGNC Symbol;Acc:HGNC:10989]",{"v":49.857433,"d":"49.86"},{"v":51.503254,"d":"51.50"},{"v":0.968044329781571,"d":"0.97"},{"v":-0.0468549803506348,"d":"-0.05"},{"v":0.987308910825072,"d":"0.99"},1,"down","no"]
[145809,0,"chr4","+",8199367,8241103,"ENST00000245105",18,4226,"ENSG00000125089","SH3TC1","GO:0008150(biological_process);GO:0005575(cellular_component)","NA","NA","NA","SH3 domain and tetratricopeptide repeats 1 [Source:HGNC Symbol;Acc:HGNC:26009]",{"v":1.959817,"d":"1.96"},{"v":2.030926,"d":"2.03"},{"v":0.964986907450099,"d":"0.96"},{"v":-0.0514187262734319,"d":"-0.05"},{"v":0.994976471146496,"d":"0.99"},1,"down","no"]
[35252,0,"chr11","+",113387791,113400418,"ENST00000303941",8,2543,"ENSG00000170209","ANKK1","GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation)","NA","NA","NA","ankyrin repeat and kinase domain containing 1 [Source:HGNC Symbol;Acc:HGNC:21027]",{"v":0.080853,"d":"0.08"},{"v":0.107466,"d":"0.11"},{"v":0.752358885601027,"d":"0.75"},{"v":-0.410507083293925,"d":"-0.41"},1,1,"down","no"]
[88558,0,"chr17","+",76742191,76769840,"ENST00000585584",7,536,"MSTRG.7259","MFSD11","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0003674(molecular_function);GO:0008150(biological_process);GO:0005575(cellular_component)","NA","NA","NA","major facilitator superfamily domain containing 11 [Source:HGNC Symbol;Acc:HGNC:25458]",{"v":0.015024,"d":"0.02"},0,"inf","inf",1,1,"up","no"]
[162350,0,"chr6","+",391768,397546,"ENST00000495137",4,757,"MSTRG.12619","IRF4","GO:0005634(nucleus);GO:0016020(membrane);GO:0005654(nucleoplasm);GO:0006355(regulation of transcription, DNA-templated);GO:0006366(transcription from RNA polymerase II promoter);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0005515(protein binding);GO:0045893(positive regulation of transcription, DNA-templated);GO:0000975(regulatory region DNA binding);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:0005829(cytosol);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0043565(sequence-specific DNA binding);GO:0008134(transcription factor binding);GO:0042110(T cell activation);GO:0060333(interferon-gamma-mediated signaling pathway);GO:0001077(transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0060337(type I interferon signaling pathway);GO:0045086(positive regulation of interleukin-2 biosynthetic process);GO:0042832(defense response to protozoan);GO:0072540(T-helper 17 cell lineage commitment);GO:0045404(positive regulation of interleukin-4 biosynthetic process);GO:0016279(protein-lysine N-methyltransferase activity);GO:0006479(protein methylation);GO:0018022(peptidyl-lysine methylation);GO:0034122(negative regulation of toll-like receptor signaling pathway);GO:0043011(myeloid dendritic cell differentiation);GO:0043388(positive regulation of DNA binding);GO:0043966(histone H3 acetylation);GO:0043967(histone H4 acetylation);GO:0045082(positive regulation of interleukin-10 biosynthetic process);GO:0045368(positive regulation of interleukin-13 biosynthetic process);GO:0045622(regulation of T-helper cell differentiation);GO:0000788(nuclear nucleosome)","04659(Th17 cell differentiation)","NA","NA","interferon regulatory factor 4 [Source:HGNC Symbol;Acc:HGNC:6119]",{"v":0.135805,"d":"0.14"},0,"inf","inf",1,1,"up","no"]
[188252,0,"chr8","-",144102817,144103756,"ENST00000531375",2,613,"MSTRG.14628","SHARPIN","GO:0046872(metal ion binding);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005515(protein binding);GO:0030054(cell junction);GO:0045202(synapse);GO:0004842(ubiquitin-protein transferase activity);GO:0043161(proteasome-mediated ubiquitin-dependent protein catabolic process);GO:0050728(negative regulation of inflammatory response);GO:0043123(positive regulation of I-kappaB kinase/NF-kappaB signaling);GO:0007249(I-kappaB kinase/NF-kappaB signaling);GO:0010803(regulation of tumor necrosis factor-mediated signaling pathway);GO:0031593(polyubiquitin binding);GO:0097039(protein linear polyubiquitination);GO:0071797(LUBAC complex);GO:0032403(protein complex binding);GO:0042802(identical protein binding);GO:0007005(mitochondrion organization);GO:0007420(brain development);GO:0008544(epidermis development);GO:0030262(apoptotic nuclear changes);GO:0031424(keratinization);GO:0051260(protein homooligomerization);GO:2000348(regulation of CD40 signaling pathway);GO:0014069(postsynaptic density);GO:0030425(dendrite)","04217(Necroptosis);04621(NOD-like receptor signaling pathway)","NA","NA","SHANK associated RH domain interactor [Source:HGNC Symbol;Acc:HGNC:25321]",0,{"v":0.038486,"d":"0.04"},"-inf","-inf",1,1,"down","no"]
[103291,0,"chr19","-",47489754,47493640,"ENST00000593905",6,548,"MSTRG.8274","NAPA","GO:0006810(transport);GO:0016020(membrane);GO:0006886(intracellular protein transport);GO:0015031(protein transport);GO:0005886(plasma membrane);GO:0000149(SNARE binding);GO:0019905(syntaxin binding);GO:0032403(protein complex binding);GO:0007420(brain development);GO:0010807(regulation of synaptic vesicle priming);GO:0030182(neuron differentiation);GO:0032781(positive regulation of ATPase activity);GO:0035249(synaptic transmission, glutamatergic);GO:0035494(SNARE complex disassembly);GO:0043241(protein complex disassembly);GO:0045176(apical protein localization);GO:0043195(terminal bouton);GO:0043209(myelin sheath);GO:0070044(synaptobrevin 2-SNAP-25-syntaxin-1a complex);GO:0005515(protein binding);GO:0016192(vesicle-mediated transport);GO:0000139(Golgi membrane);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0006890(retrograde vesicle-mediated transport, Golgi to ER);GO:0031201(SNARE complex);GO:0061025(membrane fusion);GO:0006888(ER to Golgi vesicle-mediated transport);GO:0048208(COPII vesicle coating);GO:0006891(intra-Golgi vesicle-mediated transport);GO:0005483(soluble NSF attachment protein activity);GO:0005774(vacuolar membrane);GO:0005622(intracellular)","04721(Synaptic vesicle cycle)","NA","NA","NSF attachment protein alpha [Source:HGNC Symbol;Acc:HGNC:7641]",{"v":0.571812,"d":"0.57"},0,"inf","inf",1,1,"up","no"]
[190328,0,"chr9","-",38540569,38545372,"ENST00000625242",3,2665,"ENSG00000283486","FAM95C","NA","NA","NA","NA","family with sequence similarity 95 member C [Source:HGNC Symbol;Acc:HGNC:45272]",0,0,1,0,1,1,"no","no"]
[62107,0,"chr15","+",45252230,45277845,"ENST00000347644",18,4374,"ENSG00000137860","SLC28A2","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005887(integral component of plasma membrane);GO:0005886(plasma membrane);GO:0005337(nucleoside transmembrane transporter activity);GO:0005415(nucleoside:sodium symporter activity);GO:1901642(nucleoside transmembrane transport);GO:0006139(nucleobase-containing compound metabolic process);GO:0015211(purine nucleoside transmembrane transporter activity);GO:0015860(purine nucleoside transmembrane transport)","NA","NA","NA","solute carrier family 28 member 2 [Source:HGNC Symbol;Acc:HGNC:11002]",0,{"v":7.306E-3,"d":"0.01"},"-inf","-inf",1,1,"down","no"]
[191977,0,"chr9","-",95481966,95506610,"ENST00000551630",4,539,"ENSG00000185920","PTCH1","GO:0048471(perinuclear region of cytoplasm);GO:0043433(negative regulation of sequence-specific DNA binding transcription factor activity);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005515(protein binding);GO:0007224(smoothened signaling pathway);GO:0060037(pharyngeal system development);GO:0005886(plasma membrane);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0030666(endocytic vesicle membrane);GO:0009887(animal organ morphogenesis);GO:0009953(dorsal/ventral pattern formation);GO:0005901(caveola);GO:0005794(Golgi apparatus);GO:0045668(negative regulation of osteoblast differentiation);GO:0071397(cellular response to cholesterol);GO:0015485(cholesterol binding);GO:0040015(negative regulation of multicellular organism growth);GO:0010875(positive regulation of cholesterol efflux);GO:0072001(renal system development);GO:0007420(brain development);GO:0043231(intracellular membrane-bounded organelle);GO:0060170(ciliary membrane);GO:0008589(regulation of smoothened signaling pathway);GO:0016485(protein processing);GO:0045879(negative regulation of smoothened signaling pathway);GO:0061053(somite development);GO:0072661(protein targeting to plasma membrane);GO:0030326(embryonic limb morphogenesis);GO:0030332(cyclin binding);GO:0005113(patched binding);GO:0005119(smoothened binding);GO:0008158(hedgehog receptor activity);GO:0008201(heparin binding);GO:0032403(protein complex binding);GO:0097108(hedgehog family protein binding);GO:0001658(branching involved in ureteric bud morphogenesis);GO:0001701(in utero embryonic development);GO:0001709(cell fate determination);GO:0001841(neural tube formation);GO:0001843(neural tube closure);GO:0003007(heart morphogenesis);GO:0007165(signal transduction);GO:0007346(regulation of mitotic cell cycle);GO:0007389(pattern specification process);GO:0008285(negative regulation of cell proliferation);GO:0008544(epidermis development);GO:0009612(response to mechanical stimulus);GO:0009957(epidermal cell fate specification);GO:0010157(response to chlorate);GO:0014070(response to organic cyclic compound);GO:0021522(spinal cord motor neuron differentiation);GO:0021532(neural tube patterning);GO:0021904(dorsal/ventral neural tube patterning);GO:0021997(neural plate axis specification);GO:0030850(prostate gland development);GO:0030879(mammary gland development);GO:0032355(response to estradiol);GO:0032526(response to retinoic acid);GO:0032880(regulation of protein localization);GO:0035108(limb morphogenesis);GO:0035137(hindlimb morphogenesis);GO:0040008(regulation of growth);GO:0042127(regulation of cell proliferation);GO:0042493(response to drug);GO:0042593(glucose homeostasis);GO:0043616(keratinocyte proliferation);GO:0045606(positive regulation of epidermal cell differentiation);GO:0045892(negative regulation of transcription, DNA-templated);GO:0045893(positive regulation of transcription, DNA-templated);GO:0048568(embryonic organ development);GO:0050680(negative regulation of epithelial cell proliferation);GO:0051782(negative regulation of cell division);GO:0060603(mammary gland duct morphogenesis);GO:0060644(mammary gland epithelial cell differentiation);GO:0060831(smoothened signaling pathway involved in dorsal/ventral neural tube patterning);GO:0061005(cell differentiation involved in kidney development);GO:0071679(commissural neuron axon guidance);GO:0072203(cell proliferation involved in metanephros development);GO:0005634(nucleus);GO:0005929(cilium);GO:0014069(postsynaptic density);GO:0030496(midbody);GO:0044294(dendritic growth cone);GO:0044295(axonal growth cone)","04340(Hedgehog signaling pathway);04024(cAMP signaling pathway);04360(Axon guidance);05200(Pathways in cancer);05205(Proteoglycans in cancer);05217(Basal cell carcinoma)","NA","NA","patched 1 [Source:HGNC Symbol;Acc:HGNC:9585]",0,0,1,0,1,1,"no","no"]
[32476,0,"chr11","-",70667839,70826757,"ENST00000468619",6,2775,"ENSG00000162105","SHANK2","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005886(plasma membrane);GO:0042995(cell projection);GO:0005515(protein binding);GO:0030054(cell junction);GO:0045202(synapse);GO:0045211(postsynaptic membrane);GO:0005575(cellular_component);GO:0005829(cytosol);GO:0030426(growth cone);GO:0014069(postsynaptic density);GO:0043197(dendritic spine);GO:0017124(SH3 domain binding);GO:0016324(apical plasma membrane);GO:0060170(ciliary membrane);GO:0008328(ionotropic glutamate receptor complex);GO:0043025(neuronal cell body);GO:0031526(brush border membrane);GO:0007612(learning);GO:0043005(neuron projection);GO:0001917(photoreceptor inner segment);GO:0005883(neurofilament);GO:0007416(synapse assembly);GO:0035176(social behavior);GO:0030534(adult behavior);GO:0071625(vocalization behavior);GO:0035255(ionotropic glutamate receptor binding);GO:0030160(GKAP/Homer scaffold activity);GO:0060291(long-term synaptic potentiation);GO:0060292(long term synaptic depression);GO:0001750(photoreceptor outer segment);GO:0008022(protein C-terminus binding);GO:0007420(brain development);GO:0007584(response to nutrient);GO:0007613(memory);GO:0035640(exploration behavior);GO:0051968(positive regulation of synaptic transmission, glutamatergic);GO:0048786(presynaptic active zone)","04724(Glutamatergic synapse)","NA","NA","SH3 and multiple ankyrin repeat domains 2 [Source:HGNC Symbol;Acc:HGNC:14295]",0,{"v":0.011244,"d":"0.01"},"-inf","-inf",1,1,"down","no"]
[134301,0,"chr3","+",28349146,28435157,"ENST00000420223",6,816,"MSTRG.10772","ZCWPW2","GO:0008270(zinc ion binding);GO:0046872(metal ion binding)","NA","NA","NA","zinc finger CW-type and PWWP domain containing 2 [Source:HGNC Symbol;Acc:HGNC:23574]",0,0,1,0,1,1,"no","no"]
[110780,0,"chr2","-",70214352,70229318,"ENST00000454815",9,911,"MSTRG.8800","TIA1","GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0006915(apoptotic process);GO:0005515(protein binding);GO:0005737(cytoplasm);GO:1903608(protein localization to cytoplasmic stress granule);GO:0008543(fibroblast growth factor receptor signaling pathway);GO:0048024(regulation of mRNA splicing, via spliceosome);GO:0010494(cytoplasmic stress granule);GO:0008143(poly(A) binding);GO:0017091(AU-rich element binding);GO:0017148(negative regulation of translation);GO:0042036(negative regulation of cytokine biosynthetic process);GO:1904037(positive regulation of epithelial cell apoptotic process);GO:0030529(intracellular ribonucleoprotein complex);GO:0097165(nuclear stress granule)","NA","NA","NA","TIA1 cytotoxic granule associated RNA binding protein [Source:HGNC Symbol;Acc:HGNC:11802]",{"v":0.275735,"d":"0.28"},0,"inf","inf",1,1,"up","no"]
[63467,0,"chr15","-",64075405,64093857,"ENST00000559950",4,561,"MSTRG.5173","FAM96A","GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0005634(nucleus);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0005515(protein binding);GO:0007059(chromosome segregation);GO:0003674(molecular_function);GO:0008150(biological_process);GO:0005575(cellular_component)","NA","NA","NA","family with sequence similarity 96 member A [Source:HGNC Symbol;Acc:HGNC:26235]",{"v":0.0544,"d":"0.05"},{"v":0.444083,"d":"0.44"},{"v":0.122499622818257,"d":"0.12"},{"v":-3.02915078777436,"d":"-3.03"},1,1,"down","no"]
[40296,0,"chr12","-",32820889,32824139,"ENST00000552612",3,901,"ENSG00000057294","PKP2","GO:0008285(negative regulation of cell proliferation);GO:0030336(negative regulation of cell migration);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0007155(cell adhesion);GO:0005886(plasma membrane);GO:0030054(cell junction);GO:0005515(protein binding);GO:0065009(regulation of molecular function);GO:0016337(single organismal cell-cell adhesion);GO:0003674(molecular_function);GO:0045296(cadherin binding);GO:0031424(keratinization);GO:0032947(protein complex scaffold);GO:0016021(integral component of membrane);GO:0017080(sodium channel regulator activity);GO:0044325(ion channel binding);GO:0005912(adherens junction);GO:0005911(cell-cell junction);GO:0007507(heart development);GO:0055010(ventricular cardiac muscle tissue morphogenesis);GO:0086002(cardiac muscle cell action potential involved in contraction);GO:0086091(regulation of heart rate by cardiac conduction);GO:0070268(cornification);GO:2000810(regulation of bicellular tight junction assembly);GO:0001533(cornified envelope);GO:0030057(desmosome);GO:0014704(intercalated disc);GO:0005882(intermediate filament);GO:0005080(protein kinase C binding);GO:0086064(cell communication by electrical coupling involved in cardiac conduction);GO:0055088(lipid homeostasis);GO:0086001(cardiac muscle cell action potential);GO:0045294(alpha-catenin binding);GO:0086083(cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication);GO:0002159(desmosome assembly);GO:0086073(bundle of His cell-Purkinje myocyte adhesion involved in cell communication);GO:0098911(regulation of ventricular cardiac muscle cell action potential);GO:0086005(ventricular cardiac muscle cell action potential);GO:0016264(gap junction assembly);GO:0010765(positive regulation of sodium ion transport);GO:0090002(establishment of protein localization to plasma membrane);GO:0045110(intermediate filament bundle assembly);GO:0086019(cell-cell signaling involved in cardiac conduction);GO:0019215(intermediate filament binding);GO:0034334(adherens junction maintenance);GO:0048496(maintenance of animal organ identity)","05412(Arrhythmogenic right ventricular cardiomyopathy (ARVC))","NA","NA","plakophilin 2 [Source:HGNC Symbol;Acc:HGNC:9024]",0,0,1,0,1,1,"no","no"]
[181168,0,"chr8","+",10672653,10689756,"ENST00000523723",4,1919,"ENSG00000171060","C8orf74","GO:0005515(protein binding)","NA","NA","NA","chromosome 8 open reading frame 74 [Source:HGNC Symbol;Acc:HGNC:32296]",{"v":0.009286,"d":"0.01"},0,"inf","inf",1,1,"up","no"]
[176243,0,"chr7","-",95404863,95435072,"ENST00000633531",9,1653,"ENSG00000105854","PON2","GO:0005576(extracellular region);GO:0004064(arylesterase activity);GO:0016020(membrane);GO:0046872(metal ion binding);GO:0016787(hydrolase activity);GO:0005886(plasma membrane);GO:0042802(identical protein binding);GO:0019372(lipoxygenase pathway);GO:0009636(response to toxic substance);GO:0102007(acyl-L-homoserine-lactone lactonohydrolase activity);GO:0019439(aromatic compound catabolic process);GO:0006979(response to oxidative stress);GO:0005634(nucleus);GO:0005739(mitochondrion);GO:0005764(lysosome);GO:0043231(intracellular membrane-bounded organelle);GO:0016021(integral component of membrane)","NA","NA","NA","paraoxonase 2 [Source:HGNC Symbol;Acc:HGNC:9205]",{"v":0.569864,"d":"0.57"},0,"inf","inf",1,1,"up","no"]
[78523,0,"chr17","+",7014753,7017506,"ENST00000546760",5,764,"MSTRG.6383","C17orf49","GO:0005634(nucleus);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0016569(covalent chromatin modification);GO:0003677(DNA binding);GO:0071339(MLL1 complex);GO:0016589(NURF complex)","NA","NA","NA","chromosome 17 open reading frame 49 [Source:HGNC Symbol;Acc:HGNC:28737]",{"v":0.015484,"d":"0.02"},{"v":2.33069,"d":"2.33"},{"v":0.00664352616607099,"d":"0.01"},{"v":-7.23383510453414,"d":"-7.23"},1,1,"down","no"]
[74045,0,"chr16","+",66428238,66438017,"ENST00000618932",2,437,"MSTRG.5990","BEAN1","GO:0016020(membrane);GO:0016021(integral component of membrane)","NA","NA","NA","brain expressed associated with NEDD4 1 [Source:HGNC Symbol;Acc:HGNC:24160]",0,{"v":0.097442,"d":"0.10"},"-inf","-inf",1,1,"down","no"]
[10511,0,"chr1","+",150157017,150158986,"ENST00000485470",2,638,"MSTRG.907","PLEKHO1","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0007520(myoblast fusion);GO:0008360(regulation of cell shape);GO:0051451(myoblast migration);GO:0072673(lamellipodium morphogenesis);GO:0032587(ruffle membrane);GO:0036195(muscle cell projection membrane)","NA","NA","NA","pleckstrin homology domain containing O1 [Source:HGNC Symbol;Acc:HGNC:24310]",{"v":0.021636,"d":"0.02"},{"v":0.356584,"d":"0.36"},{"v":0.0606757454064119,"d":"0.06"},{"v":-4.04273626266485,"d":"-4.04"},1,1,"down","no"]
[66984,0,"chr15","+",99566483,99645739,"ENST00000559903",4,574,"ENSG00000068305","MEF2A","GO:0005634(nucleus);GO:0046983(protein dimerization activity);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0000977(RNA polymerase II regulatory region sequence-specific DNA binding);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0010613(positive regulation of cardiac muscle hypertrophy);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0006366(transcription from RNA polymerase II promoter);GO:0005515(protein binding);GO:0006915(apoptotic process);GO:0007275(multicellular organism development);GO:0007399(nervous system development);GO:0030154(cell differentiation);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:0007507(heart development);GO:0003682(chromatin binding);GO:0007517(muscle organ development);GO:0043565(sequence-specific DNA binding);GO:0005667(transcription factor complex);GO:0000165(MAPK cascade);GO:0000790(nuclear chromatin);GO:0046982(protein heterodimerization activity);GO:0001085(RNA polymerase II transcription factor binding);GO:0000981(RNA polymerase II transcription factor activity, sequence-specific DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0001077(transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0042826(histone deacetylase binding);GO:0071277(cellular response to calcium ion);GO:0051149(positive regulation of muscle cell differentiation);GO:0000002(mitochondrial genome maintenance);GO:0048813(dendrite morphogenesis);GO:0035035(histone acetyltransferase binding);GO:0046332(SMAD binding);GO:0001105(RNA polymerase II transcription coactivator activity);GO:0033613(activating transcription factor binding);GO:0048311(mitochondrion distribution);GO:0055005(ventricular cardiac myofibril assembly);GO:0061337(cardiac conduction);GO:0070375(ERK5 cascade);GO:0003705(transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding);GO:0019901(protein kinase binding);GO:0045893(positive regulation of transcription, DNA-templated)","04371(Apelin signaling pathway);04022(cGMP - PKG signaling pathway);05418(Fluid shear stress and atherosclerosis)","NA","NA","myocyte enhancer factor 2A [Source:HGNC Symbol;Acc:HGNC:6993]",0,{"v":0.132116,"d":"0.13"},"-inf","-inf",1,1,"down","no"]
[21141,0,"chr10","-",72562711,72626074,"ENST00000604025",3,580,"MSTRG.1777","MICU1","GO:0005509(calcium ion binding);GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0046872(metal ion binding);GO:0005739(mitochondrion);GO:0005743(mitochondrial inner membrane);GO:0006811(ion transport);GO:0006816(calcium ion transport);GO:0042802(identical protein binding);GO:0005515(protein binding);GO:0005758(mitochondrial intermembrane space);GO:0005622(intracellular);GO:0046982(protein heterodimerization activity);GO:0006952(defense response);GO:0051260(protein homooligomerization);GO:0006851(mitochondrial calcium ion transmembrane transport);GO:0051560(mitochondrial calcium ion homeostasis);GO:0051561(positive regulation of mitochondrial calcium ion concentration);GO:0070509(calcium ion import);GO:0032592(integral component of mitochondrial membrane);GO:0034704(calcium channel complex);GO:0036444(mitochondrial calcium uptake);GO:1990246(uniplex complex)","NA","NA","NA","mitochondrial calcium uptake 1 [Source:HGNC Symbol;Acc:HGNC:1530]",{"v":0.604062,"d":"0.60"},{"v":0.101685,"d":"0.10"},{"v":5.94052220091459,"d":"5.94"},{"v":2.57058975654054,"d":"2.57"},1,1,"up","no"]
[198341,0,"chrX","+",73944346,73999368,"ENST00000602546",5,762,"ENSG00000225470","JPX","NA","NA","NA","NA","JPX transcript, XIST activator (non-protein coding) [Source:HGNC Symbol;Acc:HGNC:37191]",{"v":0.498023,"d":"0.50"},{"v":0.825029,"d":"0.83"},{"v":0.603643023457357,"d":"0.60"},{"v":-0.728232460135141,"d":"-0.73"},1,1,"down","no"]
[67454,0,"chr16","+",569976,577234,"ENST00000422307",4,2052,"ENSG00000007541","PIGQ","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016740(transferase activity);GO:0016757(transferase activity, transferring glycosyl groups);GO:0006506(GPI anchor biosynthetic process);GO:0017176(phosphatidylinositol N-acetylglucosaminyltransferase activity);GO:0005789(endoplasmic reticulum membrane);GO:0005975(carbohydrate metabolic process);GO:0016254(preassembly of GPI anchor in ER membrane);GO:0000506(glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex)","00563(Glycosylphosphatidylinositol(GPI)-anchor biosynthesis)","NA","NA","phosphatidylinositol glycan anchor biosynthesis class Q [Source:HGNC Symbol;Acc:HGNC:14135]",{"v":0.025307,"d":"0.03"},0,"inf","inf",1,1,"up","no"]
[186176,0,"chr8","-",101719473,102124814,"ENST00000522206",5,585,"ENSG00000104490","NCALD","GO:0046872(metal ion binding);GO:0034220(ion transmembrane transport);GO:0005509(calcium ion binding);GO:0003779(actin binding);GO:0005829(cytosol);GO:0005515(protein binding);GO:0016192(vesicle-mediated transport);GO:0070062(extracellular exosome);GO:0015631(tubulin binding);GO:0005622(intracellular);GO:0030276(clathrin binding);GO:0030130(clathrin coat of trans-Golgi network vesicle);GO:0015276(ligand-gated ion channel activity);GO:0043014(alpha-tubulin binding);GO:0003073(regulation of systemic arterial blood pressure);GO:0019722(calcium-mediated signaling)","04740(Olfactory transduction)","NA","NA","neurocalcin delta [Source:HGNC Symbol;Acc:HGNC:7655]",{"v":0.18098,"d":"0.18"},{"v":0.021993,"d":"0.02"},{"v":8.22898194880189,"d":"8.23"},{"v":3.04071395819686,"d":"3.04"},1,1,"up","no"]
[98317,0,"chr19","+",17422285,17425318,"ENST00000524382",6,908,"MSTRG.7964","MVB12A","GO:0005794(Golgi apparatus);GO:0005654(nucleoplasm);GO:0000813(ESCRT I complex);GO:0006810(transport);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0015031(protein transport);GO:0005829(cytosol);GO:0005856(cytoskeleton);GO:0005813(centrosome);GO:0005815(microtubule organizing center);GO:0008289(lipid binding);GO:0005515(protein binding);GO:0005768(endosome);GO:0031902(late endosome membrane);GO:0070062(extracellular exosome);GO:0016197(endosomal transport);GO:0016236(macroautophagy);GO:0019058(viral life cycle);GO:0036258(multivesicular body assembly);GO:0039702(viral budding via host ESCRT complex);GO:0075733(intracellular transport of virus);GO:0010008(endosome membrane);GO:0043657(host cell);GO:0017124(SH3 domain binding);GO:0043130(ubiquitin binding);GO:0048524(positive regulation of viral process);GO:0031982(vesicle);GO:0043162(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway);GO:0042058(regulation of epidermal growth factor receptor signaling pathway);GO:0019075(virus maturation);GO:1903772(regulation of viral budding via host ESCRT complex)","04144(Endocytosis)","NA","NA","multivesicular body subunit 12A [Source:HGNC Symbol;Acc:HGNC:25153]",{"v":0.617355,"d":"0.62"},{"v":0.410255,"d":"0.41"},{"v":1.50480798527745,"d":"1.50"},{"v":0.589579409668596,"d":"0.59"},1,1,"up","no"]
[159112,0,"chr5","-",140370891,140401367,"ENST00000507521",2,549,"ENSG00000249637","AC008438.1","NA","NA","NA","NA","NA",{"v":0.280953,"d":"0.28"},{"v":0.393035,"d":"0.39"},{"v":0.714829468113527,"d":"0.71"},{"v":-0.484328985654924,"d":"-0.48"},1,1,"down","no"]
[33857,0,"chr11","-",85958817,86068929,"ENST00000630913",19,2261,"MSTRG.2788","PICALM","GO:0048471(perinuclear region of cytoplasm);GO:0005634(nucleus);GO:0016020(membrane);GO:0043231(intracellular membrane-bounded organelle);GO:0006897(endocytosis);GO:0005794(Golgi apparatus);GO:0031410(cytoplasmic vesicle);GO:0005543(phospholipid binding);GO:0005545(1-phosphatidylinositol binding);GO:0030276(clathrin binding);GO:0048268(clathrin coat assembly);GO:0030136(clathrin-coated vesicle);GO:0005905(clathrin-coated pit);GO:0005515(protein binding);GO:0005829(cytosol);GO:0045296(cadherin binding);GO:0061024(membrane organization);GO:0016192(vesicle-mediated transport);GO:0045893(positive regulation of transcription, DNA-templated);GO:0006461(protein complex assembly);GO:0042734(presynaptic membrane);GO:0030132(clathrin coat of coated pit);GO:0006898(receptor-mediated endocytosis);GO:0030122(AP-2 adaptor complex);GO:0016197(endosomal transport);GO:0050750(low-density lipoprotein particle receptor binding);GO:0032050(clathrin heavy chain binding);GO:0032880(regulation of protein localization);GO:0048261(negative regulation of receptor-mediated endocytosis);GO:0045211(postsynaptic membrane);GO:1901216(positive regulation of neuron death);GO:1902004(positive regulation of amyloid-beta formation);GO:0097418(neurofibrillary tangle);GO:0045056(transcytosis);GO:0031623(receptor internalization);GO:0030100(regulation of endocytosis);GO:0072583(clathrin-dependent endocytosis);GO:0005769(early endosome);GO:0017137(Rab GTPase binding);GO:0035615(clathrin adaptor activity);GO:0008283(cell proliferation);GO:0010629(negative regulation of gene expression);GO:0016188(synaptic vesicle maturation);GO:0035459(cargo loading into vesicle);GO:0043547(positive regulation of GTPase activity);GO:0055072(iron ion homeostasis);GO:0098711(iron ion import across plasma membrane);GO:1902959(regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process);GO:1902961(positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process);GO:1902963(negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process);GO:0009986(cell surface);GO:0031982(vesicle);GO:0043025(neuronal cell body);GO:0070381(endosome to plasma membrane transport vesicle);GO:0007409(axonogenesis);GO:0007611(learning or memory);GO:0030097(hemopoiesis);GO:0048813(dendrite morphogenesis);GO:0090647(modulation of age-related behavioral decline);GO:1900223(positive regulation of amyloid-beta clearance);GO:0005622(intracellular)","NA","NA","NA","phosphatidylinositol binding clathrin assembly protein [Source:HGNC Symbol;Acc:HGNC:15514]",{"v":1.249568,"d":"1.25"},{"v":0.218891,"d":"0.22"},{"v":5.70863123655153,"d":"5.71"},{"v":2.5131448708142,"d":"2.51"},1,1,"up","no"]
[49399,0,"chr13","-",30196443,30196881,"ENST00000623049",1,439,"ENSG00000279499","AL157770.1","NA","NA","NA","NA","NA",{"v":0.203735,"d":"0.20"},0,"inf","inf",1,1,"up","no"]
[194848,0,"chr9","-",136738167,136742004,"ENST00000494294",3,2505,"ENSG00000187922","LCN10","GO:0006810(transport);GO:0005576(extracellular region)","NA","NA","NA","lipocalin 10 [Source:HGNC Symbol;Acc:HGNC:20892]",0,{"v":0.465977,"d":"0.47"},"-inf","-inf",1,1,"down","no"]
[81142,0,"chr17","+",28357642,28361177,"ENST00000555264",7,674,"MSTRG.6549","TMEM199","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005783(endoplasmic reticulum);GO:0005515(protein binding);GO:0031410(cytoplasmic vesicle);GO:0006879(cellular iron ion homeostasis);GO:0030663(COPI-coated vesicle membrane);GO:0033116(endoplasmic reticulum-Golgi intermediate compartment membrane);GO:0036295(cellular response to increased oxygen levels);GO:0007042(lysosomal lumen acidification);GO:1905146(lysosomal protein catabolic process);GO:0016471(vacuolar proton-transporting V-type ATPase complex);GO:0005764(lysosome)","NA","NA","NA","transmembrane protein 199 [Source:HGNC Symbol;Acc:HGNC:18085]",{"v":0.073976,"d":"0.07"},{"v":0.55404,"d":"0.55"},{"v":0.133521045411884,"d":"0.13"},{"v":-2.90486093935345,"d":"-2.90"},1,1,"down","no"]
[41716,0,"chr12","-",51379546,51392867,"ENST00000604426",3,538,"ENSG00000139629","GALNT6","GO:0048471(perinuclear region of cytoplasm);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0046872(metal ion binding);GO:0016740(transferase activity);GO:0030246(carbohydrate binding);GO:0016757(transferase activity, transferring glycosyl groups);GO:0005794(Golgi apparatus);GO:0000139(Golgi membrane);GO:0006486(protein glycosylation);GO:0006493(protein O-linked glycosylation);GO:0016266(O-glycan processing);GO:0004653(polypeptide N-acetylgalactosaminyltransferase activity)","00512(Mucin type O-glycan biosynthesis)","NA","NA","polypeptide N-acetylgalactosaminyltransferase 6 [Source:HGNC Symbol;Acc:HGNC:4128]",{"v":0.035032,"d":"0.04"},0,"inf","inf",1,1,"up","no"]
[51433,0,"chr13","-",98793487,98831793,"ENST00000400228",15,3147,"MSTRG.4073","DOCK9","GO:0005622(intracellular);GO:0007264(small GTPase mediated signal transduction);GO:0043547(positive regulation of GTPase activity);GO:0005085(guanyl-nucleotide exchange factor activity);GO:0016020(membrane);GO:0005515(protein binding);GO:0008150(biological_process);GO:0005829(cytosol);GO:0045296(cadherin binding);GO:0012505(endomembrane system);GO:0007596(blood coagulation)","NA","NA","NA","dedicator of cytokinesis 9 [Source:HGNC Symbol;Acc:HGNC:14132]",{"v":0.036224,"d":"0.04"},{"v":0.004038,"d":"0.00"},{"v":8.97077761267954,"d":"8.97"},{"v":3.16523304750041,"d":"3.17"},1,1,"up","no"]
[62852,0,"chr15","+",56393654,56394698,"ENST00000559546",2,632,"ENSG00000151575","TEX9","GO:0005515(protein binding)","NA","NA","NA","testis expressed 9 [Source:HGNC Symbol;Acc:HGNC:29585]",0,0,1,0,1,1,"no","no"]
[171194,0,"chr7","-",903957,905138,"ENST00000481406",2,395,"MSTRG.13429","ADAP1","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0043547(positive regulation of GTPase activity);GO:0005515(protein binding);GO:0005096(GTPase activator activity);GO:0007166(cell surface receptor signaling pathway);GO:0043087(regulation of GTPase activity);GO:0043533(inositol 1,3,4,5 tetrakisphosphate binding);GO:0005547(phosphatidylinositol-3,4,5-trisphosphate binding)","NA","NA","NA","ArfGAP with dual PH domains 1 [Source:HGNC Symbol;Acc:HGNC:16486]",{"v":0.207873,"d":"0.21"},{"v":0.044794,"d":"0.04"},{"v":4.64064383622807,"d":"4.64"},{"v":2.21432497666666,"d":"2.21"},1,1,"up","no"]
[28948,0,"chr11","-",47821376,47822167,"ENST00000527126",2,527,"MSTRG.2381","NUP160","GO:0006810(transport);GO:0051028(mRNA transport);GO:0005634(nucleus);GO:0015031(protein transport);GO:0005515(protein binding);GO:0006406(mRNA export from nucleus);GO:0005643(nuclear pore);GO:0000776(kinetochore);GO:0005829(cytosol);GO:0075733(intracellular transport of virus);GO:0043657(host cell);GO:0007062(sister chromatid cohesion);GO:0016032(viral process);GO:0016925(protein sumoylation);GO:0060964(regulation of gene silencing by miRNA);GO:0006110(regulation of glycolytic process);GO:0006409(tRNA export from nucleus);GO:0007077(mitotic nuclear envelope disassembly);GO:0019083(viral transcription);GO:1900034(regulation of cellular response to heat);GO:0005635(nuclear envelope);GO:0005487(nucleocytoplasmic transporter activity);GO:0031080(nuclear pore outer ring)","03013(RNA transport)","NA","NA","nucleoporin 160 [Source:HGNC Symbol;Acc:HGNC:18017]",{"v":0.537533,"d":"0.54"},0,"inf","inf",1,1,"up","no"]
[7300,0,"chr1","-",74705972,74733022,"ENST00000370871",8,1292,"ENSG00000116791","CRYZ","GO:0003723(RNA binding);GO:0005737(cytoplasm);GO:0008270(zinc ion binding);GO:0005829(cytosol);GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0070062(extracellular exosome);GO:0007601(visual perception);GO:0003730(mRNA 3'-UTR binding);GO:0051289(protein homotetramerization);GO:0070402(NADPH binding);GO:0003960(NADPH:quinone reductase activity);GO:0042178(xenobiotic catabolic process)","NA","NA","NA","crystallin zeta [Source:HGNC Symbol;Acc:HGNC:2419]",0,0,1,0,1,1,"no","no"]
[161962,0,"chr5","+",179698406,179708336,"ENST00000502296",5,825,"MSTRG.12595","CANX","GO:0005783(endoplasmic reticulum);GO:0005509(calcium ion binding);GO:0006457(protein folding);GO:0051082(unfolded protein binding);GO:0003723(RNA binding);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0046872(metal ion binding);GO:0030246(carbohydrate binding);GO:0005789(endoplasmic reticulum membrane);GO:0005515(protein binding);GO:0042470(melanosome);GO:0070062(extracellular exosome);GO:0031012(extracellular matrix);GO:0019886(antigen processing and presentation of exogenous peptide antigen via MHC class II);GO:0035722(interleukin-12-mediated signaling pathway);GO:0005788(endoplasmic reticulum lumen);GO:0072583(clathrin-dependent endocytosis);GO:0002474(antigen processing and presentation of peptide antigen via MHC class I);GO:0071556(integral component of lumenal side of endoplasmic reticulum membrane);GO:0048488(synaptic vesicle endocytosis);GO:0044233(ER-mitochondrion membrane contact site);GO:0009306(protein secretion);GO:0034975(protein folding in endoplasmic reticulum);GO:0034185(apolipoprotein binding);GO:0035255(ionotropic glutamate receptor binding);GO:0007568(aging);GO:0061077(chaperone-mediated protein folding);GO:0005737(cytoplasm);GO:0005790(smooth endoplasmic reticulum);GO:0005791(rough endoplasmic reticulum);GO:0005840(ribosome);GO:0030424(axon);GO:0032839(dendrite cytoplasm);GO:0043025(neuronal cell body);GO:0043197(dendritic spine);GO:0043209(myelin sheath);GO:0043234(protein complex)","04141(Protein processing in endoplasmic reticulum);04145(Phagosome);04612(Antigen processing and presentation);04918(Thyroid hormone synthesis);05166(HTLV-I infection)","NA","NA","calnexin [Source:HGNC Symbol;Acc:HGNC:1473]",0,{"v":0.000297,"d":"0.00"},"-inf","-inf",1,1,"down","no"]
[173535,0,"chr7","-",43951910,44019151,"ENST00000454572",9,2076,"MSTRG.13619","AC004951.4","NA","NA","NA","NA","NA",0,0,1,0,1,1,"no","no"]
[122078,0,"chr20","+",13793180,13809001,"ENST00000464269",5,550,"ENSG00000101247","NDUFAF5","GO:0016020(membrane);GO:0008168(methyltransferase activity);GO:0016740(transferase activity);GO:0032259(methylation);GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0005743(mitochondrial inner membrane);GO:0008152(metabolic process);GO:0005739(mitochondrion);GO:0005515(protein binding);GO:0003674(molecular_function);GO:0032981(mitochondrial respiratory chain complex I assembly);GO:0031314(extrinsic component of mitochondrial inner membrane);GO:0030961(peptidyl-arginine hydroxylation)","NA","NA","NA","NADH:ubiquinone oxidoreductase complex assembly factor 5 [Source:HGNC Symbol;Acc:HGNC:15899]",{"v":0.039783,"d":"0.04"},{"v":0.084672,"d":"0.08"},{"v":0.46984835600907,"d":"0.47"},{"v":-1.08973289412896,"d":"-1.09"},1,1,"down","no"]
[100534,0,"chr19","-",36543616,36573288,"ENST00000334116",6,5238,"ENSG00000186020","ZNF529","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0005622(intracellular)","NA","NA","NA","zinc finger protein 529 [Source:HGNC Symbol;Acc:HGNC:29328]",0,{"v":0.287494,"d":"0.29"},"-inf","-inf",1,1,"down","no"]
[176802,0,"chr7","-",100156605,100156669,"ENST00000584344",1,65,"MSTRG.13800","MIR4658","NA","NA","NA","NA","microRNA 4658 [Source:HGNC Symbol;Acc:HGNC:41673]",{"v":0.712053,"d":"0.71"},{"v":0.123182,"d":"0.12"},{"v":5.78049552694387,"d":"5.78"},{"v":2.53119317155327,"d":"2.53"},1,1,"up","no"]
[44631,0,"chr12","-",76053328,76084685,"ENST00000550934",9,851,"MSTRG.3567","NAP1L1","GO:0005634(nucleus);GO:0003723(RNA binding);GO:0016020(membrane);GO:0006334(nucleosome assembly);GO:0005515(protein binding);GO:0042470(melanosome);GO:0008284(positive regulation of cell proliferation);GO:0006260(DNA replication)","NA","NA","NA","nucleosome assembly protein 1 like 1 [Source:HGNC Symbol;Acc:HGNC:7637]",{"v":0.134369,"d":"0.13"},{"v":0.01902,"d":"0.02"},{"v":7.06461619348055,"d":"7.06"},{"v":2.82061118394164,"d":"2.82"},1,1,"up","no"]
[175033,0,"chr7","+",74210006,74229831,"ENST00000488266",12,1694,"MSTRG.13713","LAT2","GO:0042113(B cell activation);GO:0002764(immune response-regulating signaling pathway);GO:0005622(intracellular);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005886(plasma membrane);GO:0002376(immune system process);GO:0002250(adaptive immune response);GO:0038095(Fc-epsilon receptor signaling pathway);GO:0042629(mast cell granule);GO:0070062(extracellular exosome);GO:0005515(protein binding);GO:0043303(mast cell degranulation);GO:0019722(calcium-mediated signaling);GO:0035556(intracellular signal transduction);GO:0045121(membrane raft);GO:0042169(SH2 domain binding);GO:0050853(B cell receptor signaling pathway)","NA","NA","NA","linker for activation of T-cells family member 2 [Source:HGNC Symbol;Acc:HGNC:12749]",0,0,1,0,1,1,"no","no"]
[26767,0,"chr11","+",12226207,12244034,"ENST00000526475",5,538,"MSTRG.2260","MICAL2","GO:0005634(nucleus);GO:0003779(actin binding);GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0010735(positive regulation of transcription via serum response element binding);GO:0043914(NADPH:sulfur oxidoreductase activity);GO:0030042(actin filament depolymerization);GO:0046872(metal ion binding);GO:0004497(monooxygenase activity);GO:0071949(FAD binding);GO:0007507(heart development);GO:0007010(cytoskeleton organization);GO:0016709(oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen);GO:0001947(heart looping);GO:0019417(sulfur oxidation)","NA","NA","NA","microtubule associated monooxygenase, calponin and LIM domain containing 2 [Source:HGNC Symbol;Acc:HGNC:24693]",0,0,1,0,1,1,"no","no"]
[5144,0,"chr1","+",43736263,43930221,"ENST00000531993",8,786,"MSTRG.497","ST3GAL3","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016740(transferase activity);GO:0008373(sialyltransferase activity);GO:0016757(transferase activity, transferring glycosyl groups);GO:0006486(protein glycosylation);GO:0097503(sialylation);GO:0005794(Golgi apparatus);GO:0005576(extracellular region);GO:0032580(Golgi cisterna membrane);GO:0000139(Golgi membrane);GO:0016266(O-glycan processing);GO:0018146(keratan sulfate biosynthetic process);GO:0009311(oligosaccharide metabolic process);GO:0003836(beta-galactoside (CMP) alpha-2,3-sialyltransferase activity);GO:0018279(protein N-linked glycosylation via asparagine);GO:0008118(N-acetyllactosaminide alpha-2,3-sialyltransferase activity)","00515(Mannose type O-glycan biosyntheis);00514(Other types of O-glycan biosynthesis);00533(Glycosaminoglycan biosynthesis - keratan sulfate);00601(Glycosphingolipid biosynthesis - lacto and neolacto series)","K00781","EC:2.4.99.6","ST3 beta-galactoside alpha-2,3-sialyltransferase 3 [Source:HGNC Symbol;Acc:HGNC:10866]",0,0,1,0,1,1,"no","no"]
[3937,0,"chr1","+",32669256,32680651,"ENST00000482190",7,616,"MSTRG.383","RBBP4","GO:0005634(nucleus);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0016569(covalent chromatin modification);GO:0016575(histone deacetylation);GO:0000790(nuclear chromatin);GO:0005515(protein binding);GO:0007049(cell cycle);GO:0006260(DNA replication);GO:0043234(protein complex);GO:0035098(ESC/E(Z) complex);GO:0034080(CENP-A containing nucleosome assembly);GO:1901796(regulation of signal transduction by p53 class mediator);GO:0004407(histone deacetylase activity);GO:0008285(negative regulation of cell proliferation);GO:0006335(DNA replication-dependent nucleosome assembly);GO:0006336(DNA replication-independent nucleosome assembly);GO:0042826(histone deacetylase binding);GO:0045814(negative regulation of gene expression, epigenetic);GO:0016589(NURF complex);GO:0031492(nucleosomal DNA binding);GO:0016580(Sin3 complex);GO:0043044(ATP-dependent chromatin remodeling);GO:0016581(NuRD complex);GO:0051726(regulation of cell cycle);GO:0042393(histone binding);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:0000980(RNA polymerase II distal enhancer sequence-specific DNA binding);GO:0031497(chromatin assembly);GO:0008094(DNA-dependent ATPase activity);GO:0006338(chromatin remodeling);GO:0033186(CAF-1 complex);GO:0060416(response to growth hormone)","04218(Cellular senescence)","NA","NA","RB binding protein 4, chromatin remodeling factor [Source:HGNC Symbol;Acc:HGNC:9887]",{"v":1.134E-3,"d":"0.00"},{"v":0.102595,"d":"0.10"},{"v":0.0110531702324675,"d":"0.01"},{"v":-6.49939597195049,"d":"-6.50"},1,1,"down","no"]
[177795,0,"chr7","+",108571715,108574760,"ENST00000465725",2,343,"MSTRG.13914","DNAJB9","GO:0005737(cytoplasm);GO:0005783(endoplasmic reticulum);GO:0005730(nucleolus);GO:0005788(endoplasmic reticulum lumen);GO:0005515(protein binding);GO:0005789(endoplasmic reticulum membrane);GO:0070062(extracellular exosome);GO:0030433(ubiquitin-dependent ERAD pathway);GO:0036498(IRE1-mediated unfolded protein response);GO:0051787(misfolded protein binding)","NA","NA","NA","DnaJ heat shock protein family (Hsp40) member B9 [Source:HGNC Symbol;Acc:HGNC:6968]",{"v":0.561362,"d":"0.56"},{"v":0.648021,"d":"0.65"},{"v":0.86627130910881,"d":"0.87"},{"v":-0.207109158843872,"d":"-0.21"},1,1,"down","no"]
[118211,0,"chr2","-",202883589,202884535,"ENST00000463824",2,491,"MSTRG.9369","WDR12","GO:0005634(nucleus);GO:0005515(protein binding);GO:0005654(nucleoplasm);GO:0042254(ribosome biogenesis);GO:0005730(nucleolus);GO:0006364(rRNA processing);GO:0008283(cell proliferation);GO:0043021(ribonucleoprotein complex binding);GO:0000463(maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA));GO:0000466(maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA));GO:0042273(ribosomal large subunit biogenesis);GO:0030687(preribosome, large subunit precursor);GO:0070545(PeBoW complex);GO:0007219(Notch signaling pathway)","NA","NA","NA","WD repeat domain 12 [Source:HGNC Symbol;Acc:HGNC:14098]",0,{"v":0.031392,"d":"0.03"},"-inf","-inf",1,1,"down","no"]
[30420,0,"chr11","-",62852609,62855467,"ENST00000538266",7,347,"MSTRG.2487","SNHG1","NA","NA","NA","NA","small nucleolar RNA host gene 1 [Source:HGNC Symbol;Acc:HGNC:32688]",0,{"v":0.134096,"d":"0.13"},"-inf","-inf",1,1,"down","no"]
[148655,0,"chr4","+",82275071,82276600,"ENST00000504996",1,1530,"ENSG00000234568","BIN2P1","NA","NA","NA","NA","bridging integrator 2 pseudogene 1 [Source:HGNC Symbol;Acc:HGNC:43660]",{"v":0.01635,"d":"0.02"},{"v":0.01988,"d":"0.02"},{"v":0.822434607645875,"d":"0.82"},{"v":-0.282027121176841,"d":"-0.28"},1,1,"down","no"]
[69741,0,"chr16","+",11965107,11968068,"ENST00000053243",3,994,"MSTRG.5664","TNFRSF17","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0007165(signal transduction);GO:0005886(plasma membrane);GO:0004872(receptor activity);GO:0002376(immune system process);GO:0002250(adaptive immune response);GO:0033209(tumor necrosis factor-mediated signaling pathway);GO:0012505(endomembrane system);GO:0007275(multicellular organism development);GO:0008283(cell proliferation);GO:0002260(lymphocyte homeostasis)","04060(Cytokine-cytokine receptor interaction);04672(Intestinal immune network for IgA production)","K05153","NA","TNF receptor superfamily member 17 [Source:HGNC Symbol;Acc:HGNC:11913]",{"v":2.113331,"d":"2.11"},{"v":0.310891,"d":"0.31"},{"v":6.79765898659016,"d":"6.80"},{"v":2.76503798902059,"d":"2.77"},1,1,"up","no"]
[173947,0,"chr7","+",48089265,48103413,"ENST00000436673",7,918,"MSTRG.13643","UPP1","GO:0009116(nucleoside metabolic process);GO:0003824(catalytic activity);GO:0016763(transferase activity, transferring pentosyl groups);GO:0005737(cytoplasm);GO:0016740(transferase activity);GO:0016757(transferase activity, transferring glycosyl groups);GO:0044206(UMP salvage);GO:0004850(uridine phosphorylase activity);GO:0009166(nucleotide catabolic process);GO:0005829(cytosol);GO:0006139(nucleobase-containing compound metabolic process);GO:0043097(pyrimidine nucleoside salvage);GO:0046135(pyrimidine nucleoside catabolic process);GO:0006218(uridine catabolic process);GO:0006220(pyrimidine nucleotide metabolic process);GO:0042149(cellular response to glucose starvation);GO:0046108(uridine metabolic process)","00240(Pyrimidine metabolism);00983(Drug metabolism - other enzymes)","NA","NA","uridine phosphorylase 1 [Source:HGNC Symbol;Acc:HGNC:12576]",{"v":0.000219,"d":"0.00"},{"v":0.021449,"d":"0.02"},{"v":0.0102102662128771,"d":"0.01"},{"v":-6.61383570759519,"d":"-6.61"},1,1,"down","no"]
[188547,0,"chr8","-",144876497,144901479,"ENST00000528258",6,677,"ENSG00000196150","ZNF250","GO:0003676(nucleic acid binding);GO:0006355(regulation of transcription, DNA-templated);GO:0005622(intracellular);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding)","NA","NA","NA","zinc finger protein 250 [Source:HGNC Symbol;Acc:HGNC:13044]",0,0,1,0,1,1,"no","no"]
[163677,0,"chr6","-",28329632,28354204,"ENST00000439628",3,580,"ENSG00000235109","ZSCAN31","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding)","NA","NA","NA","zinc finger and SCAN domain containing 31 [Source:HGNC Symbol;Acc:HGNC:14097]",{"v":0.088624,"d":"0.09"},{"v":0.127957,"d":"0.13"},{"v":0.692607672890111,"d":"0.69"},{"v":-0.529889724708275,"d":"-0.53"},1,1,"down","no"]
[133777,0,"chr3","+",15601370,15635580,"ENST00000494021",2,558,"MSTRG.10705","BTD","GO:0016787(hydrolase activity);GO:0016810(hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds);GO:0006807(nitrogen compound metabolic process);GO:0005576(extracellular region);GO:0005615(extracellular space);GO:0016811(hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides);GO:0070062(extracellular exosome);GO:0005759(mitochondrial matrix);GO:0007417(central nervous system development);GO:0006768(biotin metabolic process);GO:0047708(biotinidase activity)","00780(Biotin metabolism);04977(Vitamin digestion and absorption)","NA","NA","biotinidase [Source:HGNC Symbol;Acc:HGNC:1122]",{"v":0.081017,"d":"0.08"},0,"inf","inf",1,1,"up","no"]
[200502,0,"chrX","+",147911956,147937523,"ENST00000616614",12,1409,"MSTRG.15471","FMR1","GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0006397(mRNA processing);GO:0006810(transport);GO:0008380(RNA splicing);GO:0051028(mRNA transport);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005829(cytosol);GO:0030529(intracellular ribonucleoprotein complex);GO:0005694(chromosome);GO:0042803(protein homodimerization activity);GO:0005886(plasma membrane);GO:0042995(cell projection);GO:0005515(protein binding);GO:0006974(cellular response to DNA damage stimulus);GO:0048471(perinuclear region of cytoplasm);GO:0030054(cell junction);GO:0045202(synapse);GO:0045211(postsynaptic membrane);GO:0007399(nervous system development);GO:0005654(nucleoplasm);GO:0043022(ribosome binding);GO:0045727(positive regulation of translation);GO:0005730(nucleolus);GO:0031047(gene silencing by RNA);GO:0030425(dendrite);GO:0008017(microtubule binding);GO:0000775(chromosome, centromeric region);GO:0003729(mRNA binding);GO:0030424(axon);GO:0030426(growth cone);GO:0043204(perikaryon);GO:0098586(cellular response to virus);GO:0006417(regulation of translation);GO:0003682(chromatin binding);GO:0044325(ion channel binding);GO:0070840(dynein complex binding);GO:0042802(identical protein binding);GO:2000637(positive regulation of gene silencing by miRNA);GO:0005845(mRNA cap binding complex);GO:0014069(postsynaptic density);GO:0043197(dendritic spine);GO:0016032(viral process);GO:0043005(neuron projection);GO:0046982(protein heterodimerization activity);GO:0042734(presynaptic membrane);GO:0000381(regulation of alternative mRNA splicing, via spliceosome);GO:0003730(mRNA 3'-UTR binding);GO:0051491(positive regulation of filopodium assembly);GO:0031369(translation initiation factor binding);GO:0033592(RNA strand annealing activity);GO:0035613(RNA stem-loop binding);GO:0048027(mRNA 5'-UTR binding);GO:0036464(cytoplasmic ribonucleoprotein granule);GO:0035064(methylated histone binding);GO:1901386(negative regulation of voltage-gated calcium channel activity);GO:0032797(SMN complex);GO:0015030(Cajal body);GO:0030371(translation repressor activity);GO:0045947(negative regulation of translational initiation);GO:0060999(positive regulation of dendritic spine development);GO:0051489(regulation of filopodium assembly);GO:0005844(polysome);GO:0034644(cellular response to UV);GO:2001022(positive regulation of response to DNA damage stimulus);GO:0008266(poly(U) RNA binding);GO:0002092(positive regulation of receptor internalization);GO:0032433(filopodium tip);GO:0019897(extrinsic component of plasma membrane);GO:0043679(axon terminus);GO:0035198(miRNA binding);GO:0043488(regulation of mRNA stability);GO:0046928(regulation of neurotransmitter secretion);GO:0072711(cellular response to hydroxyurea);GO:0033129(positive regulation of histone phosphorylation);GO:0002151(G-quadruplex RNA binding);GO:0042788(polysomal ribosome);GO:0034046(poly(G) binding);GO:0098908(regulation of neuronal action potential);GO:0060998(regulation of dendritic spine development);GO:1990904(ribonucleoprotein complex);GO:0035197(siRNA binding);GO:1990825(sequence-specific mRNA binding);GO:0007215(glutamate receptor signaling pathway);GO:0044830(modulation by host of viral RNA genome replication);GO:0060964(regulation of gene silencing by miRNA);GO:1900453(negative regulation of long term synaptic depression);GO:1901254(positive regulation of intracellular transport of viral material);GO:1901800(positive regulation of proteasomal protein catabolic process);GO:1902373(negative regulation of mRNA catabolic process);GO:1902416(positive regulation of mRNA binding);GO:2000301(negative regulation of synaptic vesicle exocytosis);GO:2000766(negative regulation of cytoplasmic translation);GO:0010369(chromocenter);GO:0019034(viral replication complex);GO:0071598(neuronal ribonucleoprotein granule);GO:0097386(glial cell projection);GO:0098793(presynapse);GO:0098794(postsynapse);GO:1902737(dendritic filopodium);GO:1990124(messenger ribonucleoprotein complex);GO:1990812(growth cone filopodium)","03013(RNA transport)","NA","NA","fragile X mental retardation 1 [Source:HGNC Symbol;Acc:HGNC:3775]",{"v":0.050186,"d":"0.05"},{"v":0.425948,"d":"0.43"},{"v":0.117821893752289,"d":"0.12"},{"v":-3.08532044813831,"d":"-3.09"},1,1,"down","no"]
[67494,0,"chr16","-",634438,636351,"ENST00000397664",4,604,"ENSG00000130731","METTL26","NA","NA","NA","NA","methyltransferase like 26 [Source:HGNC Symbol;Acc:HGNC:14141]",0,{"v":0.929017,"d":"0.93"},"-inf","-inf",1,1,"down","no"]
[99866,0,"chr19","-",34766968,34773200,"ENST00000588760",3,948,"ENSG00000153896","ZNF599","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0005622(intracellular);GO:0005515(protein binding)","NA","NA","NA","zinc finger protein 599 [Source:HGNC Symbol;Acc:HGNC:26408]",{"v":0.263596,"d":"0.26"},0,"inf","inf",1,1,"up","no"]
[197213,0,"chrX","-",49179806,49186528,"ENST00000376317",4,574,"MSTRG.15293","PRICKLE3","GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0005515(protein binding);GO:0008150(biological_process);GO:0005575(cellular_component)","NA","NA","NA","prickle planar cell polarity protein 3 [Source:HGNC Symbol;Acc:HGNC:6645]",0,0,1,0,1,1,"no","no"]
[79692,0,"chr17","-",15636204,15684297,"ENST00000581224",8,815,"ENSG00000221926","TRIM16","GO:0005737(cytoplasm);GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0005829(cytosol);GO:0003677(DNA binding);GO:0005622(intracellular);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0045893(positive regulation of transcription, DNA-templated);GO:0019966(interleukin-1 binding);GO:0050718(positive regulation of interleukin-1 beta secretion);GO:0043967(histone H4 acetylation);GO:0016605(PML body);GO:0043966(histone H3 acetylation);GO:0045618(positive regulation of keratinocyte differentiation);GO:0032089(NACHT domain binding);GO:0032526(response to retinoic acid);GO:0046683(response to organophosphorus);GO:0048386(positive regulation of retinoic acid receptor signaling pathway);GO:0060416(response to growth hormone);GO:0003676(nucleic acid binding);GO:0006355(regulation of transcription, DNA-templated)","NA","NA","NA","tripartite motif containing 16 [Source:HGNC Symbol;Acc:HGNC:17241]",{"v":0.037435,"d":"0.04"},{"v":0.143824,"d":"0.14"},{"v":0.260283401935699,"d":"0.26"},{"v":-1.94184477972062,"d":"-1.94"},1,1,"down","no"]
[191736,0,"chr9","-",92316094,92324675,"ENST00000535807",7,575,"ENSG00000198000","NOL8","GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005730(nucleolus);GO:0006364(rRNA processing);GO:0005515(protein binding);GO:1902570(protein localization to nucleolus)","NA","NA","NA","nucleolar protein 8 [Source:HGNC Symbol;Acc:HGNC:23387]",{"v":0.01207,"d":"0.01"},0,"inf","inf",1,1,"up","no"]
[161031,0,"chr5","+",171251866,171252982,"ENST00000523223",1,1117,"ENSG00000253213","AC010306.1","NA","NA","NA","NA","NA",{"v":0.046018,"d":"0.05"},0,"inf","inf",1,1,"up","no"]
[125386,0,"chr20","+",63273204,63285663,"ENST00000522403",11,995,"MSTRG.9888","ARFGAP1","GO:0006810(transport);GO:0005737(cytoplasm);GO:0015031(protein transport);GO:0046872(metal ion binding);GO:0005794(Golgi apparatus);GO:0043547(positive regulation of GTPase activity);GO:0005515(protein binding);GO:0005096(GTPase activator activity);GO:0016192(vesicle-mediated transport);GO:0005829(cytosol);GO:0006890(retrograde vesicle-mediated transport, Golgi to ER);GO:0006888(ER to Golgi vesicle-mediated transport);GO:0036498(IRE1-mediated unfolded protein response);GO:0030100(regulation of endocytosis);GO:0014069(postsynaptic density);GO:0045202(synapse)","04144(Endocytosis)","NA","NA","ADP ribosylation factor GTPase activating protein 1 [Source:HGNC Symbol;Acc:HGNC:15852]",0,0,1,0,1,1,"no","no"]
[108636,0,"chr2","+",33524430,33530944,"ENST00000477927",3,477,"ENSG00000152689","RASGRP3","GO:0007264(small GTPase mediated signal transduction);GO:0046872(metal ion binding);GO:0035556(intracellular signal transduction);GO:0005509(calcium ion binding);GO:0043547(positive regulation of GTPase activity);GO:0005515(protein binding);GO:0004871(signal transducer activity);GO:0005096(GTPase activator activity);GO:0043087(regulation of GTPase activity);GO:0007265(Ras protein signal transduction);GO:0005085(guanyl-nucleotide exchange factor activity);GO:0005886(plasma membrane);GO:0005887(integral component of plasma membrane);GO:0000165(MAPK cascade);GO:0005088(Ras guanyl-nucleotide exchange factor activity);GO:0019992(diacylglycerol binding);GO:0005622(intracellular);GO:0017016(Ras GTPase binding);GO:0019900(kinase binding);GO:0005737(cytoplasm);GO:0032045(guanyl-nucleotide exchange factor complex);GO:0048471(perinuclear region of cytoplasm)","04014(Ras signaling pathway);04015(Rap1 signaling pathway);04010(MAPK signaling pathway);04662(B cell receptor signaling pathway);05200(Pathways in cancer)","NA","NA","RAS guanyl releasing protein 3 [Source:HGNC Symbol;Acc:HGNC:14545]",0,0,1,0,1,1,"no","no"]
[11416,0,"chr1","-",154479481,154502113,"ENST00000304760",6,6243,"ENSG00000169291","SHE","GO:0009967(positive regulation of signal transduction);GO:0005515(protein binding);GO:0007165(signal transduction);GO:0005070(SH3/SH2 adaptor activity)","NA","NA","NA","Src homology 2 domain containing E [Source:HGNC Symbol;Acc:HGNC:27004]",{"v":0.01235,"d":"0.01"},0,"inf","inf",1,1,"up","no"]
[107999,0,"chr2","-",26581202,26641368,"ENST00000288861",7,773,"ENSG00000157884","CIB4","GO:0046872(metal ion binding);GO:0005509(calcium ion binding);GO:0000287(magnesium ion binding);GO:0005515(protein binding)","NA","NA","NA","calcium and integrin binding family member 4 [Source:HGNC Symbol;Acc:HGNC:33703]",{"v":0.047932,"d":"0.05"},{"v":0.006886,"d":"0.01"},{"v":6.96079000871333,"d":"6.96"},{"v":2.79925105276561,"d":"2.80"},1,1,"up","no"]
[155698,0,"chr5","-",72295549,72320238,"ENST00000523654",4,429,"MSTRG.12110","MRPS27","GO:0030529(intracellular ribonucleoprotein complex);GO:0005840(ribosome);GO:0005739(mitochondrion);GO:0005515(protein binding);GO:0005743(mitochondrial inner membrane);GO:0070125(mitochondrial translational elongation);GO:0070126(mitochondrial translational termination)","NA","NA","NA","mitochondrial ribosomal protein S27 [Source:HGNC Symbol;Acc:HGNC:14512]",{"v":0.141542,"d":"0.14"},{"v":0.204813,"d":"0.20"},{"v":0.691079179544267,"d":"0.69"},{"v":-0.533077079799715,"d":"-0.53"},1,1,"down","no"]
[77521,0,"chr17","-",1638140,1640557,"ENST00000570902",4,1060,"ENSG00000074660","SCARF1","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0007155(cell adhesion);GO:0005044(scavenger receptor activity);GO:0007165(signal transduction);GO:0006898(receptor-mediated endocytosis);GO:0005886(plasma membrane);GO:0004888(transmembrane signaling receptor activity);GO:0030666(endocytic vesicle membrane);GO:0010976(positive regulation of neuron projection development);GO:0016322(neuron remodeling);GO:0006707(cholesterol catabolic process);GO:0030169(low-density lipoprotein particle binding);GO:0016358(dendrite development);GO:0048680(positive regulation of axon regeneration)","NA","NA","NA","scavenger receptor class F member 1 [Source:HGNC Symbol;Acc:HGNC:16820]",0,{"v":0.019349,"d":"0.02"},"-inf","-inf",1,1,"down","no"]
[10399,0,"chr1","-",149055630,149075866,"ENST00000483630",14,1915,"ENSG00000269713","NBPF9","GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process)","NA","NA","NA","NBPF member 9 [Source:HGNC Symbol;Acc:HGNC:31991]",0,0,1,0,1,1,"no","no"]
[198332,0,"chrX","+",73944324,73999114,"ENST00000602938",5,581,"ENSG00000225470","JPX","NA","NA","NA","NA","JPX transcript, XIST activator (non-protein coding) [Source:HGNC Symbol;Acc:HGNC:37191]",0,{"v":0.110645,"d":"0.11"},"-inf","-inf",1,1,"down","no"]
[163557,0,"chr6","+",27252986,27256624,"ENST00000485603",3,3411,"ENSG00000112812","PRSS16","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0008233(peptidase activity);GO:0006508(proteolysis);GO:0008236(serine-type peptidase activity);GO:0016787(hydrolase activity);GO:0031410(cytoplasmic vesicle);GO:0005764(lysosome);GO:0005768(endosome);GO:0030163(protein catabolic process);GO:0008239(dipeptidyl-peptidase activity)","NA","NA","NA","protease, serine 16 [Source:HGNC Symbol;Acc:HGNC:9480]",{"v":0.051018,"d":"0.05"},0,"inf","inf",1,1,"up","no"]
[90270,0,"chr18","-",2972360,2982809,"ENST00000581568",3,278,"MSTRG.7384","LPIN2","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0003713(transcription coactivator activity);GO:0016787(hydrolase activity);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0006629(lipid metabolic process);GO:0005829(cytosol);GO:0008195(phosphatidate phosphatase activity);GO:0016311(dephosphorylation);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0006631(fatty acid metabolic process);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0009062(fatty acid catabolic process);GO:0019432(triglyceride biosynthetic process);GO:0006656(phosphatidylcholine biosynthetic process);GO:0006646(phosphatidylethanolamine biosynthetic process)","00561(Glycerolipid metabolism);00564(Glycerophospholipid metabolism)","NA","NA","lipin 2 [Source:HGNC Symbol;Acc:HGNC:14450]",0,{"v":0.344643,"d":"0.34"},"-inf","-inf",1,1,"down","no"]
[111628,0,"chr2","+",84971093,85028056,"ENST00000456682",3,661,"MSTRG.8858","KCMF1","GO:0003676(nucleic acid binding);GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0016740(transferase activity);GO:0005576(extracellular region);GO:0043312(neutrophil degranulation);GO:1904813(ficolin-1-rich granule lumen)","NA","NA","NA","potassium channel modulatory factor 1 [Source:HGNC Symbol;Acc:HGNC:20589]",{"v":0.071087,"d":"0.07"},0,"inf","inf",1,1,"up","no"]
[137875,0,"chr3","+",66998307,67003697,"ENST00000484414",2,568,"ENSG00000163376","KBTBD8","GO:0005737(cytoplasm);GO:0005794(Golgi apparatus);GO:0005856(cytoskeleton);GO:0005819(spindle);GO:0004842(ubiquitin-protein transferase activity);GO:0005515(protein binding);GO:0005829(cytosol);GO:0043687(post-translational protein modification);GO:0006417(regulation of translation);GO:0042787(protein ubiquitination involved in ubiquitin-dependent protein catabolic process);GO:0031463(Cul3-RING ubiquitin ligase complex);GO:0006513(protein monoubiquitination);GO:0014029(neural crest formation);GO:0014032(neural crest cell development)","NA","NA","NA","kelch repeat and BTB domain containing 8 [Source:HGNC Symbol;Acc:HGNC:30691]",{"v":0.108069,"d":"0.11"},{"v":0.15299,"d":"0.15"},{"v":0.706379501928231,"d":"0.71"},{"v":-0.501484616135921,"d":"-0.50"},1,1,"down","no"]
[175774,0,"chr7","+",87345681,87399481,"ENST00000419147",19,2959,"ENSG00000005469","CROT","GO:0006810(transport);GO:0043231(intracellular membrane-bounded organelle);GO:0016740(transferase activity);GO:0016746(transferase activity, transferring acyl groups);GO:0006629(lipid metabolic process);GO:0006631(fatty acid metabolic process);GO:0005777(peroxisome);GO:0005102(receptor binding);GO:0005782(peroxisomal matrix);GO:0033540(fatty acid beta-oxidation using acyl-CoA oxidase);GO:0006635(fatty acid beta-oxidation);GO:0006091(generation of precursor metabolites and energy);GO:0009437(carnitine metabolic process);GO:0008458(carnitine O-octanoyltransferase activity);GO:0015908(fatty acid transport);GO:0015936(coenzyme A metabolic process);GO:0051791(medium-chain fatty acid metabolic process);GO:0005739(mitochondrion)","04146(Peroxisome)","K05940","EC:2.3.1.137","carnitine O-octanoyltransferase [Source:HGNC Symbol;Acc:HGNC:2366]",0,{"v":0.479246,"d":"0.48"},"-inf","-inf",1,1,"down","no"]
[127085,0,"chr21","-",37225299,37267351,"ENST00000399001",5,821,"MSTRG.10031","DSCR3","GO:0005634(nucleus);GO:0006886(intracellular protein transport);GO:0003674(molecular_function);GO:0008150(biological_process);GO:0005768(endosome);GO:0008565(protein transporter activity)","NA","NA","NA","DSCR3 arrestin fold containing [Source:HGNC Symbol;Acc:HGNC:3044]",{"v":0.207476,"d":"0.21"},{"v":0.599082,"d":"0.60"},{"v":0.346323207841331,"d":"0.35"},{"v":-1.52980902610553,"d":"-1.53"},1,1,"down","no"]
[120884,0,"chr2","+",240562983,240564013,"ENST00000497221",2,488,"MSTRG.9515","DUSP28","GO:0016787(hydrolase activity);GO:0008138(protein tyrosine/serine/threonine phosphatase activity);GO:0016791(phosphatase activity);GO:0006470(protein dephosphorylation);GO:0016311(dephosphorylation);GO:0004721(phosphoprotein phosphatase activity);GO:0004725(protein tyrosine phosphatase activity);GO:0035335(peptidyl-tyrosine dephosphorylation)","NA","NA","NA","dual specificity phosphatase 28 [Source:HGNC Symbol;Acc:HGNC:33237]",0,{"v":0.087465,"d":"0.09"},"-inf","-inf",1,1,"down","no"]
[63641,0,"chr15","-",65156686,65185342,"ENST00000558958",9,1493,"MSTRG.5198","CLPX","GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0005739(mitochondrion);GO:0005743(mitochondrial inner membrane);GO:0006457(protein folding);GO:0005759(mitochondrial matrix);GO:0016887(ATPase activity);GO:0051082(unfolded protein binding);GO:0005515(protein binding);GO:0010952(positive regulation of peptidase activity);GO:0046034(ATP metabolic process);GO:0004176(ATP-dependent peptidase activity);GO:0042645(mitochondrial nucleoid);GO:0016504(peptidase activator activity);GO:0051603(proteolysis involved in cellular protein catabolic process);GO:0009368(endopeptidase Clp complex);GO:0009841(mitochondrial endopeptidase Clp complex)","NA","NA","NA","caseinolytic mitochondrial matrix peptidase chaperone subunit [Source:HGNC Symbol;Acc:HGNC:2088]",{"v":0.157801,"d":"0.16"},0,"inf","inf",1,1,"up","no"]
[190961,0,"chr9","+",70043581,70226970,"ENST00000377182",14,3616,"MSTRG.14798","MAMDC2","GO:0016020(membrane);GO:0005576(extracellular region);GO:0005578(proteinaceous extracellular matrix);GO:0005783(endoplasmic reticulum)","NA","NA","NA","MAM domain containing 2 [Source:HGNC Symbol;Acc:HGNC:23673]",{"v":0.02504,"d":"0.03"},{"v":0.017706,"d":"0.02"},{"v":1.41420987235965,"d":"1.41"},{"v":0.499996235666817,"d":"0.50"},1,1,"up","no"]
[135606,0,"chr3","-",46809498,46811341,"ENST00000522832",2,328,"ENSG00000226074","PRSS44","NA","NA","NA","NA","protease, serine 44 [Source:HGNC Symbol;Acc:HGNC:37324]",0,0,1,0,1,1,"no","no"]
[85176,0,"chr17","+",48910690,48927054,"ENST00000504684",5,598,"MSTRG.6991","UBE2Z","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0016740(transferase activity);GO:0016567(protein ubiquitination);GO:0005515(protein binding);GO:0006915(apoptotic process);GO:0031625(ubiquitin protein ligase binding);GO:0061630(ubiquitin protein ligase activity);GO:0043065(positive regulation of apoptotic process);GO:0061631(ubiquitin conjugating enzyme activity);GO:0042787(protein ubiquitination involved in ubiquitin-dependent protein catabolic process)","04120(Ubiquitin mediated proteolysis)","NA","NA","ubiquitin conjugating enzyme E2 Z [Source:HGNC Symbol;Acc:HGNC:25847]",{"v":0.833587,"d":"0.83"},{"v":0.297761,"d":"0.30"},{"v":2.79951706234195,"d":"2.80"},{"v":1.48517797293574,"d":"1.49"},1,1,"up","no"]
[80041,0,"chr17","-",17246835,17247887,"ENST00000486032",2,725,"MSTRG.6490","COPS3","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0005515(protein binding);GO:0008180(COP9 signalosome);GO:0043687(post-translational protein modification);GO:0007165(signal transduction);GO:0000338(protein deneddylation);GO:0006283(transcription-coupled nucleotide-excision repair);GO:0006511(ubiquitin-dependent protein catabolic process);GO:0000715(nucleotide-excision repair, DNA damage recognition);GO:0009416(response to light stimulus);GO:0001701(in utero embryonic development)","NA","NA","NA","COP9 signalosome subunit 3 [Source:HGNC Symbol;Acc:HGNC:2239]",0,0,1,0,1,1,"no","no"]
[106060,0,"chr19","-",56296068,56314839,"ENST00000587614",3,589,"ENSG00000131848","ZSCAN5A","GO:0005634(nucleus);GO:0003676(nucleic acid binding);GO:0046872(metal ion binding);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0000981(RNA polymerase II transcription factor activity, sequence-specific DNA binding)","NA","NA","NA","zinc finger and SCAN domain containing 5A [Source:HGNC Symbol;Acc:HGNC:23710]",0,0,1,0,1,1,"no","no"]
[7155,0,"chr1","+",70434851,70439232,"ENST00000482383",3,598,"ENSG00000116761","CTH","GO:0005737(cytoplasm);GO:0003824(catalytic activity);GO:0016829(lyase activity);GO:0005515(protein binding);GO:0008652(cellular amino acid biosynthetic process);GO:0030170(pyridoxal phosphate binding);GO:0042802(identical protein binding);GO:0005516(calmodulin binding);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0051289(protein homotetramerization);GO:0030968(endoplasmic reticulum unfolded protein response);GO:0019344(cysteine biosynthetic process);GO:0070814(hydrogen sulfide biosynthetic process);GO:0003962(cystathionine gamma-synthase activity);GO:0004123(cystathionine gamma-lyase activity);GO:0016846(carbon-sulfur lyase activity);GO:0044540(L-cystine L-cysteine-lyase (deaminating));GO:0047982(homocysteine desulfhydrase activity);GO:0080146(L-cysteine desulfhydrase activity);GO:0000098(sulfur amino acid catabolic process);GO:0006534(cysteine metabolic process);GO:0018272(protein-pyridoxal-5-phosphate linkage via peptidyl-N6-pyridoxal phosphate-L-lysine);GO:0019343(cysteine biosynthetic process via cystathionine);GO:0019346(transsulfuration);GO:0043066(negative regulation of apoptotic process);GO:0043123(positive regulation of I-kappaB kinase/NF-kappaB signaling);GO:0044524(protein sulfhydration);GO:0051092(positive regulation of NF-kappaB transcription factor activity);GO:0071266('de novo' L-methionine biosynthetic process);GO:1904831(positive regulation of aortic smooth muscle cell differentiation);GO:1990830(cellular response to leukemia inhibitory factor);GO:2001234(negative regulation of apoptotic signaling pathway)","00260(Glycine, serine and threonine metabolism);00270(Cysteine and methionine metabolism);00450(Selenocompound metabolism)","NA","NA","cystathionine gamma-lyase [Source:HGNC Symbol;Acc:HGNC:2501]",{"v":0.081659,"d":"0.08"},0,"inf","inf",1,1,"up","no"]
[161551,0,"chr5","+",177371107,177372143,"ENST00000503044",3,458,"MSTRG.12575","RGS14","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0035556(intracellular signal transduction);GO:0007165(signal transduction);GO:0051301(cell division);GO:0005886(plasma membrane);GO:0030695(GTPase regulator activity);GO:0043547(positive regulation of GTPase activity);GO:0005856(cytoskeleton);GO:0042995(cell projection);GO:0005515(protein binding);GO:0005057(signal transducer activity, downstream of receptor);GO:0005096(GTPase activator activity);GO:0007049(cell cycle);GO:0008017(microtubule binding);GO:0030054(cell junction);GO:0045202(synapse);GO:0045211(postsynaptic membrane);GO:0005874(microtubule);GO:0005092(GDP-dissociation inhibitor activity);GO:0030425(dendrite);GO:0000922(spindle pole);GO:0005813(centrosome);GO:0005815(microtubule organizing center);GO:0005819(spindle);GO:0007051(spindle organization);GO:0007059(chromosome segregation);GO:0014069(postsynaptic density);GO:0043197(dendritic spine);GO:0001965(G-protein alpha-subunit binding);GO:0007616(long-term memory);GO:0006979(response to oxidative stress);GO:0016605(PML body);GO:0048008(platelet-derived growth factor receptor signaling pathway);GO:0007612(learning);GO:0009968(negative regulation of signal transduction);GO:0070373(negative regulation of ERK1 and ERK2 cascade);GO:0008277(regulation of G-protein coupled receptor protein signaling pathway);GO:0019901(protein kinase binding);GO:0030159(receptor signaling complex scaffold activity);GO:0032794(GTPase activating protein binding);GO:0000278(mitotic cell cycle);GO:0006913(nucleocytoplasmic transport);GO:0008542(visual learning);GO:0010070(zygote asymmetric cell division);GO:0031914(negative regulation of synaptic plasticity);GO:0043407(negative regulation of MAP kinase activity);GO:0043620(regulation of DNA-templated transcription in response to stress);GO:0050769(positive regulation of neurogenesis);GO:0060291(long-term synaptic potentiation);GO:0016604(nuclear body);GO:0005622(intracellular);GO:0050790(regulation of catalytic activity)","04015(Rap1 signaling pathway)","NA","NA","regulator of G protein signaling 14 [Source:HGNC Symbol;Acc:HGNC:9996]",{"v":1.191989,"d":"1.19"},{"v":3.021232,"d":"3.02"},{"v":0.394537394016745,"d":"0.39"},{"v":-1.34176605040059,"d":"-1.34"},1,1,"down","no"]
[198381,0,"chrX","-",74280461,74292075,"ENST00000455395",4,654,"ENSG00000230590","FTX","NA","NA","NA","NA","FTX transcript, XIST regulator (non-protein coding) [Source:HGNC Symbol;Acc:HGNC:37190]",0,{"v":0.06046,"d":"0.06"},"-inf","-inf",1,1,"down","no"]
[90965,0,"chr18","+",13217498,13387577,"ENST00000590371",3,598,"ENSG00000168675","LDLRAD4","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0043231(intracellular membrane-bounded organelle);GO:0005654(nucleoplasm);GO:0005768(endosome);GO:0031901(early endosome membrane);GO:0009968(negative regulation of signal transduction);GO:0070412(R-SMAD binding);GO:0010719(negative regulation of epithelial to mesenchymal transition);GO:0010991(negative regulation of SMAD protein complex assembly);GO:0030336(negative regulation of cell migration);GO:0030512(negative regulation of transforming growth factor beta receptor signaling pathway);GO:0060394(negative regulation of pathway-restricted SMAD protein phosphorylation)","NA","NA","NA","low density lipoprotein receptor class A domain containing 4 [Source:HGNC Symbol;Acc:HGNC:1224]",{"v":0.048136,"d":"0.05"},0,"inf","inf",1,1,"up","no"]
[94293,0,"chr19","+",1383918,1395584,"ENST00000546172",9,869,"MSTRG.7606","NDUFS7","GO:0046872(metal ion binding);GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0005739(mitochondrion);GO:0070469(respiratory chain);GO:0051536(iron-sulfur cluster binding);GO:0051539(4 iron, 4 sulfur cluster binding);GO:0008137(NADH dehydrogenase (ubiquinone) activity);GO:0005515(protein binding);GO:0032981(mitochondrial respiratory chain complex I assembly);GO:0005759(mitochondrial matrix);GO:0048038(quinone binding);GO:0003954(NADH dehydrogenase activity);GO:0006120(mitochondrial electron transport, NADH to ubiquinone);GO:0005747(mitochondrial respiratory chain complex I);GO:0016655(oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor);GO:0002020(protease binding);GO:0005743(mitochondrial inner membrane);GO:0043005(neuron projection);GO:0043025(neuronal cell body);GO:0097060(synaptic membrane)","00190(Oxidative phosphorylation);04723(Retrograde endocannabinoid signaling);05010(Alzheimer's disease);05012(Parkinson's disease);05016(Huntington's disease);04932(Non-alcoholic fatty liver disease (NAFLD))","NA","NA","NADH:ubiquinone oxidoreductase core subunit S7 [Source:HGNC Symbol;Acc:HGNC:7714]",{"v":0.010253,"d":"0.01"},0,"inf","inf",1,1,"up","no"]
[86909,0,"chr17","+",63998455,64004285,"ENST00000225760",4,3059,"MSTRG.7098","PRR29","NA","NA","NA","NA","proline rich 29 [Source:HGNC Symbol;Acc:HGNC:25673]",{"v":0.170474,"d":"0.17"},0,"inf","inf",1,1,"up","no"]
[128874,0,"chr22","+",20965177,20967036,"ENST00000479523",2,562,"MSTRG.10172","AIFM3","GO:0046872(metal ion binding);GO:0005829(cytosol);GO:0016491(oxidoreductase activity);GO:0050660(flavin adenine dinucleotide binding);GO:0055114(oxidation-reduction process);GO:0005739(mitochondrion);GO:0051537(2 iron, 2 sulfur cluster binding);GO:0006915(apoptotic process);GO:0051536(iron-sulfur cluster binding);GO:0005783(endoplasmic reticulum);GO:0097194(execution phase of apoptosis);GO:0005743(mitochondrial inner membrane)","NA","NA","NA","apoptosis inducing factor, mitochondria associated 3 [Source:HGNC Symbol;Acc:HGNC:26398]",{"v":0.321094,"d":"0.32"},{"v":0.118211,"d":"0.12"},{"v":2.71627851891956,"d":"2.72"},{"v":1.44163141671915,"d":"1.44"},1,1,"up","no"]
[13681,0,"chr1","+",172659144,172666075,"ENST00000340030",3,917,"MSTRG.1193","FASLG","GO:0005615(extracellular space);GO:0016525(negative regulation of angiogenesis);GO:0006919(activation of cysteine-type endopeptidase activity involved in apoptotic process);GO:2000353(positive regulation of endothelial cell apoptotic process);GO:0005634(nucleus);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0005886(plasma membrane);GO:0006915(apoptotic process);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0006955(immune response);GO:0005125(cytokine activity);GO:0031410(cytoplasmic vesicle);GO:0005164(tumor necrosis factor receptor binding);GO:0005764(lysosome);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0070062(extracellular exosome);GO:0033209(tumor necrosis factor-mediated signaling pathway);GO:0043065(positive regulation of apoptotic process);GO:0005887(integral component of plasma membrane);GO:0043123(positive regulation of I-kappaB kinase/NF-kappaB signaling);GO:0007165(signal transduction);GO:0007267(cell-cell signaling);GO:0097190(apoptotic signaling pathway);GO:0097191(extrinsic apoptotic signaling pathway);GO:0097296(activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway);GO:1902041(regulation of extrinsic apoptotic signaling pathway via death domain receptors);GO:1902042(negative regulation of extrinsic apoptotic signaling pathway via death domain receptors);GO:0005102(receptor binding);GO:0043202(lysosomal lumen);GO:0060205(cytoplasmic vesicle lumen);GO:0008625(extrinsic apoptotic signaling pathway via death domain receptors);GO:0097527(necroptotic signaling pathway);GO:0005123(death receptor binding);GO:0006925(inflammatory cell apoptotic process);GO:0008284(positive regulation of cell proliferation);GO:0030644(cellular chloride ion homeostasis);GO:0032496(response to lipopolysaccharide);GO:0043525(positive regulation of neuron apoptotic process);GO:0045742(positive regulation of epidermal growth factor receptor signaling pathway);GO:0046666(retinal cell programmed cell death);GO:0048388(endosomal lumen acidification);GO:0070231(T cell apoptotic process);GO:0070266(necroptotic process);GO:0070848(response to growth factor);GO:1903514(release of sequestered calcium ion into cytosol by endoplasmic reticulum);GO:0005901(caveola);GO:0009897(external side of plasma membrane);GO:0009986(cell surface);GO:0045121(membrane raft);GO:0048471(perinuclear region of cytoplasm)","04014(Ras signaling pathway);04010(MAPK signaling pathway);04068(FoxO signaling pathway);04151(PI3K-Akt signaling pathway);04060(Cytokine-cytokine receptor interaction);04210(Apoptosis);04217(Necroptosis);04650(Natural killer cell mediated cytotoxicity);04722(Neurotrophin signaling pathway);05200(Pathways in cancer);05205(Proteoglycans in cancer);05320(Autoimmune thyroid disease);05330(Allograft rejection);05332(Graft-versus-host disease);04940(Type I diabetes mellitus);04932(Non-alcoholic fatty liver disease (NAFLD));05162(Measles);05164(Influenza A);05161(Hepatitis B);05168(Herpes simplex infection);05165(Human papillomavirus infection);05142(Chagas disease (American trypanosomiasis));05143(African trypanosomiasis);01524(Platinum drug resistance)","K04389","NA","Fas ligand [Source:HGNC Symbol;Acc:HGNC:11936]",{"v":0.172291,"d":"0.17"},{"v":0.067129,"d":"0.07"},{"v":2.56656586572122,"d":"2.57"},{"v":1.35983928487346,"d":"1.36"},1,1,"up","no"]
[141302,0,"chr3","+",142664122,142671045,"ENST00000460104",3,403,"ENSG00000120756","PLS1","GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0003779(actin binding);GO:0005509(calcium ion binding);GO:0051015(actin filament binding);GO:0070062(extracellular exosome);GO:0051017(actin filament bundle assembly);GO:0005903(brush border);GO:0005200(structural constituent of cytoskeleton);GO:0090004(positive regulation of establishment of protein localization to plasma membrane);GO:0051639(actin filament network formation);GO:0005884(actin filament);GO:0051764(actin crosslink formation);GO:0032432(actin filament bundle);GO:0001951(intestinal D-glucose absorption);GO:0032532(regulation of microvillus length);GO:0040018(positive regulation of multicellular organism growth);GO:1902896(terminal web assembly);GO:1990357(terminal web)","NA","NA","NA","plastin 1 [Source:HGNC Symbol;Acc:HGNC:9090]",0,{"v":0.874095,"d":"0.87"},"-inf","-inf",1,1,"down","no"]
[176735,0,"chr7","+",100101549,100103648,"ENST00000394061",7,813,"MSTRG.13806","AP4M1","GO:0006810(transport);GO:0006886(intracellular protein transport);GO:0015031(protein transport);GO:0016192(vesicle-mediated transport);GO:0030131(clathrin adaptor complex);GO:0005829(cytosol);GO:0005794(Golgi apparatus);GO:0005515(protein binding);GO:0005768(endosome);GO:0070062(extracellular exosome);GO:0005802(trans-Golgi network);GO:0005215(transporter activity);GO:0006895(Golgi to endosome transport);GO:0000138(Golgi trans cisterna);GO:0030119(AP-type membrane coat adaptor complex);GO:0031904(endosome lumen);GO:0032588(trans-Golgi network membrane)","04142(Lysosome)","NA","NA","adaptor related protein complex 4 mu 1 subunit [Source:HGNC Symbol;Acc:HGNC:574]",0,{"v":0.001666,"d":"0.00"},"-inf","-inf",1,1,"down","no"]
[130513,0,"chr22","-",31618491,31662215,"ENST00000460723",7,2534,"MSTRG.10401","PISD","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005743(mitochondrial inner membrane);GO:0016829(lyase activity);GO:0006629(lipid metabolic process);GO:0005739(mitochondrion);GO:0008654(phospholipid biosynthetic process);GO:0004609(phosphatidylserine decarboxylase activity);GO:0016831(carboxy-lyase activity);GO:0006646(phosphatidylethanolamine biosynthetic process);GO:0016540(protein autoprocessing);GO:0031305(integral component of mitochondrial inner membrane);GO:0005634(nucleus)","00564(Glycerophospholipid metabolism)","NA","NA","phosphatidylserine decarboxylase [Source:HGNC Symbol;Acc:HGNC:8999]",{"v":0.001831,"d":"0.00"},{"v":1.117192,"d":"1.12"},{"v":1.63893046137101E-3,"d":"0.00"},{"v":-9.25302964142879,"d":"-9.25"},1,1,"down","no"]
[22642,0,"chr10","+",97446197,97457085,"ENST00000370846",8,1280,"MSTRG.1897","ZDHHC16","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016740(transferase activity);GO:0016746(transferase activity, transferring acyl groups);GO:0019706(protein-cysteine S-palmitoyltransferase activity);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0006915(apoptotic process);GO:0016409(palmitoyltransferase activity);GO:0018345(protein palmitoylation)","NA","NA","NA","zinc finger DHHC-type containing 16 [Source:HGNC Symbol;Acc:HGNC:20714]",{"v":3.692884,"d":"3.69"},{"v":0.391808,"d":"0.39"},{"v":9.42523889251879,"d":"9.43"},{"v":3.23652918545657,"d":"3.24"},1,1,"up","no"]
[104182,0,"chr19","-",49861265,49861502,"ENST00000640501",2,151,"MSTRG.8351","PNKP","GO:0005634(nucleus);GO:0005730(nucleolus);GO:0016020(membrane);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0016787(hydrolase activity);GO:0090305(nucleic acid phosphodiester bond hydrolysis);GO:0005515(protein binding);GO:0003824(catalytic activity);GO:0008152(metabolic process);GO:0006281(DNA repair);GO:0006974(cellular response to DNA damage stimulus);GO:0004519(endonuclease activity);GO:0005654(nucleoplasm);GO:0016311(dephosphorylation);GO:0003690(double-stranded DNA binding);GO:0046404(ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity);GO:0006979(response to oxidative stress);GO:0006261(DNA-dependent DNA replication);GO:0032212(positive regulation of telomere maintenance via telomerase);GO:0051973(positive regulation of telomerase activity);GO:1904355(positive regulation of telomere capping);GO:0003684(damaged DNA binding);GO:0009314(response to radiation);GO:0010836(negative regulation of protein ADP-ribosylation);GO:0042769(DNA damage response, detection of DNA damage);GO:0017076(purine nucleotide binding);GO:0019201(nucleotide kinase activity);GO:0046403(polynucleotide 3'-phosphatase activity);GO:0000718(nucleotide-excision repair, DNA damage removal);GO:0046939(nucleotide phosphorylation);GO:0098504(DNA 3' dephosphorylation involved in DNA repair);GO:0098506(polynucleotide 3' dephosphorylation);GO:0005739(mitochondrion)","NA","NA","NA","polynucleotide kinase 3'-phosphatase [Source:HGNC Symbol;Acc:HGNC:9154]",0,0,1,0,1,1,"no","no"]
[52614,0,"chr14","-",21210923,21269410,"ENST00000556628",8,1156,"MSTRG.4143","HNRNPC","GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0019013(viral nucleocapsid);GO:0030529(intracellular ribonucleoprotein complex);GO:0006397(mRNA processing);GO:0008380(RNA splicing);GO:0005634(nucleus);GO:0016020(membrane);GO:0005654(nucleoplasm);GO:0000790(nuclear chromatin);GO:0005829(cytosol);GO:0005515(protein binding);GO:0005681(spliceosomal complex);GO:0042802(identical protein binding);GO:0070062(extracellular exosome);GO:0043234(protein complex);GO:0000398(mRNA splicing, via spliceosome);GO:0003730(mRNA 3'-UTR binding);GO:0070034(telomerase RNA binding);GO:0005697(telomerase holoenzyme complex);GO:0016070(RNA metabolic process);GO:0071013(catalytic step 2 spliceosome);GO:0001649(osteoblast differentiation);GO:0031492(nucleosomal DNA binding);GO:0043044(ATP-dependent chromatin remodeling);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:0000980(RNA polymerase II distal enhancer sequence-specific DNA binding);GO:0008266(poly(U) RNA binding);GO:1990247(N6-methyladenosine-containing RNA binding);GO:0032211(negative regulation of telomere maintenance via telomerase);GO:0070935(3'-UTR-mediated mRNA stabilization)","03040(Spliceosome)","NA","NA","heterogeneous nuclear ribonucleoprotein C (C1/C2) [Source:HGNC Symbol;Acc:HGNC:5035]",0,0,1,0,1,1,"no","no"]
[124858,0,"chr20","+",57351252,57375106,"ENST00000527947",11,1503,"MSTRG.9848","RAE1","GO:0006810(transport);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0001650(fibrillar center);GO:0051301(cell division);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0007049(cell cycle);GO:0008017(microtubule binding);GO:0000922(spindle pole);GO:0003723(RNA binding);GO:0075733(intracellular transport of virus);GO:0043657(host cell);GO:0005635(nuclear envelope);GO:0005643(nuclear pore);GO:0043130(ubiquitin binding);GO:0097431(mitotic spindle pole);GO:0016032(viral process);GO:0006406(mRNA export from nucleus);GO:0016925(protein sumoylation);GO:0006606(protein import into nucleus);GO:0060964(regulation of gene silencing by miRNA);GO:0006110(regulation of glycolytic process);GO:0006409(tRNA export from nucleus);GO:0007077(mitotic nuclear envelope disassembly);GO:0019083(viral transcription);GO:1900034(regulation of cellular response to heat);GO:0000972(transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery);GO:0006405(RNA export from nucleus);GO:0060236(regulation of mitotic spindle organization);GO:0071407(cellular response to organic cyclic compound)","03013(RNA transport);05164(Influenza A)","NA","NA","ribonucleic acid export 1 [Source:HGNC Symbol;Acc:HGNC:9828]",{"v":0.029184,"d":"0.03"},{"v":0.017788,"d":"0.02"},{"v":1.6406566224421,"d":"1.64"},{"v":0.714273324813234,"d":"0.71"},1,1,"up","no"]
[117345,0,"chr2","+",190343875,190362687,"ENST00000413239",5,613,"MSTRG.9302","INPP1","GO:0046872(metal ion binding);GO:0016787(hydrolase activity);GO:0016311(dephosphorylation);GO:0046854(phosphatidylinositol phosphorylation);GO:0005829(cytosol);GO:0007165(signal transduction);GO:0006796(phosphate-containing compound metabolic process);GO:0043647(inositol phosphate metabolic process);GO:0004441(inositol-1,4-bisphosphate 1-phosphatase activity);GO:0052829(inositol-1,3,4-trisphosphate 1-phosphatase activity)","00562(Inositol phosphate metabolism);04070(Phosphatidylinositol signaling system)","NA","NA","inositol polyphosphate-1-phosphatase [Source:HGNC Symbol;Acc:HGNC:6071]",0,0,1,0,1,1,"no","no"]
[62710,0,"chr15","-",52611625,52709817,"ENST00000561490",4,547,"ENSG00000047346","FAM214A","GO:0005515(protein binding)","NA","NA","NA","family with sequence similarity 214 member A [Source:HGNC Symbol;Acc:HGNC:25609]",0,{"v":0.100089,"d":"0.10"},"-inf","-inf",1,1,"down","no"]
[24369,0,"chr10","+",128181136,128317726,"ENST00000630252",7,3086,"ENSG00000280953","LINC01163","NA","NA","NA","NA","long intergenic non-protein coding RNA 1163 [Source:NCBI gene;Acc:101927381]",{"v":0.058298,"d":"0.06"},{"v":0.058742,"d":"0.06"},{"v":0.992441523952198,"d":"0.99"},{"v":-0.010945995744636,"d":"-0.01"},1,1,"down","no"]
[143510,0,"chr3","+",184327286,184327915,"ENST00000482303",2,493,"MSTRG.11394","EIF4G1","GO:0003723(RNA binding);GO:0016020(membrane);GO:0003743(translation initiation factor activity);GO:0006412(translation);GO:0006413(translational initiation);GO:0006446(regulation of translational initiation);GO:0005515(protein binding);GO:0008190(eukaryotic initiation factor 4E binding);GO:0005829(cytosol);GO:0045296(cadherin binding);GO:0043488(regulation of mRNA stability);GO:0000289(nuclear-transcribed mRNA poly(A) tail shortening);GO:0006417(regulation of translation);GO:0016032(viral process);GO:0010507(negative regulation of autophagy);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0008135(translation factor activity, RNA binding);GO:0007005(mitochondrion organization);GO:0005524(ATP binding);GO:0000184(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay);GO:0016281(eukaryotic translation initiation factor 4F complex);GO:1901215(negative regulation of neuron death);GO:0033138(positive regulation of peptidyl-serine phosphorylation);GO:0008284(positive regulation of cell proliferation);GO:1905606(regulation of presynapse assembly);GO:0010801(negative regulation of peptidyl-threonine phosphorylation);GO:0030307(positive regulation of cell growth);GO:0034645(cellular macromolecule biosynthetic process);GO:0022627(cytosolic small ribosomal subunit);GO:0003729(mRNA binding);GO:0031369(translation initiation factor binding);GO:0032947(protein complex scaffold);GO:0002191(cap-dependent translational initiation);GO:0032270(positive regulation of cellular protein metabolic process);GO:0032502(developmental process);GO:0060964(regulation of gene silencing by miRNA);GO:0080135(regulation of cellular response to stress);GO:1900087(positive regulation of G1/S transition of mitotic cell cycle);GO:1905537(positive regulation of eukaryotic translation initiation factor 4F complex assembly);GO:1905612(positive regulation of mRNA cap binding);GO:1905618(positive regulation of miRNA mediated inhibition of translation);GO:1905696(regulation of polysome binding);GO:2000507(positive regulation of energy homeostasis);GO:0005844(polysome);GO:0001662(behavioral fear response);GO:0045666(positive regulation of neuron differentiation)","03013(RNA transport);05416(Viral myocarditis)","NA","NA","eukaryotic translation initiation factor 4 gamma 1 [Source:HGNC Symbol;Acc:HGNC:3296]",{"v":0.067438,"d":"0.07"},{"v":0.173184,"d":"0.17"},{"v":0.389400868440503,"d":"0.39"},{"v":-1.36067199333196,"d":"-1.36"},1,1,"down","no"]
[12493,0,"chr1","+",159802424,159815661,"ENST00000368106",10,1306,"MSTRG.1106","FCRL6","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0009897(external side of plasma membrane)","NA","NA","NA","Fc receptor like 6 [Source:HGNC Symbol;Acc:HGNC:31910]",{"v":0.850834,"d":"0.85"},0,"inf","inf",1,1,"up","no"]
[156270,0,"chr5","-",81113385,81114852,"ENST00000508993",2,555,"ENSG00000249772","AC026427.1","NA","NA","NA","NA","NA",0,0,1,0,1,1,"no","no"]
[31038,0,"chr11","+",65096753,65108494,"ENST00000534557",5,854,"MSTRG.2537","VPS51","GO:0017119(Golgi transport complex);GO:0006810(transport);GO:0016021(integral component of membrane);GO:0015031(protein transport);GO:0005794(Golgi apparatus);GO:0005829(cytosol);GO:0043231(intracellular membrane-bounded organelle);GO:0005730(nucleolus);GO:0006869(lipid transport);GO:0006914(autophagy);GO:0005515(protein binding);GO:0005768(endosome);GO:0003674(molecular_function);GO:0042147(retrograde transport, endosome to Golgi);GO:0055037(recycling endosome);GO:0007030(Golgi organization);GO:0032588(trans-Golgi network membrane);GO:0048193(Golgi vesicle transport);GO:0016020(membrane);GO:0032456(endocytic recycling);GO:0007041(lysosomal transport);GO:0000938(GARP complex);GO:1990745(EARP complex);GO:0005802(trans-Golgi network)","NA","NA","NA","VPS51, GARP complex subunit [Source:HGNC Symbol;Acc:HGNC:1172]",0,0,1,0,1,1,"no","no"]
[112381,0,"chr2","+",95792220,95800166,"ENST00000444924",14,1672,"ENSG00000237510","GPAT2P1","NA","NA","NA","NA","glycerol-3-phosphate acyltransferase 2 pseudogene 1 [Source:HGNC Symbol;Acc:HGNC:52330]",{"v":0.056506,"d":"0.06"},{"v":0.007085,"d":"0.01"},{"v":7.97544107268878,"d":"7.98"},{"v":2.99556430769062,"d":"3.00"},1,1,"up","no"]
[161765,0,"chr5","+",178141672,178149991,"ENST00000513162",6,4250,"MSTRG.12586","RMND5B","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0004842(ubiquitin-protein transferase activity);GO:0043161(proteasome-mediated ubiquitin-dependent protein catabolic process);GO:0042787(protein ubiquitination involved in ubiquitin-dependent protein catabolic process);GO:0034657(GID complex)","NA","NA","NA","required for meiotic nuclear division 5 homolog B [Source:HGNC Symbol;Acc:HGNC:26181]",{"v":0.886035,"d":"0.89"},{"v":0.058312,"d":"0.06"},{"v":15.1947283577994,"d":"15.19"},{"v":3.92549897834522,"d":"3.93"},1,1,"up","no"]
[182768,0,"chr8","+",30732247,30766470,"ENST00000620074",9,1058,"ENSG00000104691","UBXN8","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005783(endoplasmic reticulum);GO:0005730(nucleolus);GO:0030433(ubiquitin-dependent ERAD pathway);GO:0003676(nucleic acid binding);GO:0090502(RNA phosphodiester bond hydrolysis, endonucleolytic);GO:0004523(RNA-DNA hybrid ribonuclease activity);GO:0005789(endoplasmic reticulum membrane);GO:0005515(protein binding);GO:0007338(single fertilization);GO:0030176(integral component of endoplasmic reticulum membrane)","NA","NA","NA","UBX domain protein 8 [Source:HGNC Symbol;Acc:HGNC:30307]",0,{"v":0.006547,"d":"0.01"},"-inf","-inf",1,1,"down","no"]
[96026,0,"chr19","-",8604936,8610735,"ENST00000593534",3,630,"ENSG00000142303","ADAMTS10","GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0016787(hydrolase activity);GO:0008233(peptidase activity);GO:0006508(proteolysis);GO:0005576(extracellular region);GO:0005578(proteinaceous extracellular matrix);GO:0004222(metalloendopeptidase activity);GO:0008237(metallopeptidase activity);GO:0005515(protein binding);GO:0003674(molecular_function);GO:0008150(biological_process);GO:0031012(extracellular matrix);GO:0001527(microfibril)","NA","NA","NA","ADAM metallopeptidase with thrombospondin type 1 motif 10 [Source:HGNC Symbol;Acc:HGNC:13201]",{"v":0.14243,"d":"0.14"},{"v":0.112394,"d":"0.11"},{"v":1.26723846468673,"d":"1.27"},{"v":0.341688031542306,"d":"0.34"},1,1,"up","no"]
[95527,0,"chr19","-",6494319,6502584,"ENST00000264071",4,2552,"ENSG00000104833","TUBB4A","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005525(GTP binding);GO:0000166(nucleotide binding);GO:0003924(GTPase activity);GO:0015630(microtubule cytoskeleton);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0005200(structural constituent of cytoskeleton);GO:0007010(cytoskeleton organization);GO:0005874(microtubule);GO:0007017(microtubule-based process);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0000086(G2/M transition of mitotic cell cycle);GO:0010389(regulation of G2/M transition of mitotic cell cycle);GO:0097711(ciliary basal body docking);GO:0005509(calcium ion binding);GO:0031115(negative regulation of microtubule polymerization);GO:0005929(cilium);GO:0033269(internode region of axon);GO:0042995(cell projection);GO:0043025(neuronal cell body);GO:0043209(myelin sheath)","04145(Phagosome);04540(Gap junction);05130(Pathogenic Escherichia coli infection)","K07375","NA","tubulin beta 4A class IVa [Source:HGNC Symbol;Acc:HGNC:20774]",{"v":0.129783,"d":"0.13"},{"v":0.584941,"d":"0.58"},{"v":0.221873659052793,"d":"0.22"},{"v":-2.1721896946333,"d":"-2.17"},1,1,"down","no"]
[31659,0,"chr11","-",66435838,66438834,"ENST00000329819",6,922,"MSTRG.2588","MRPL11","GO:0003723(RNA binding);GO:0006412(translation);GO:0005739(mitochondrion);GO:0030529(intracellular ribonucleoprotein complex);GO:0003735(structural constituent of ribosome);GO:0005840(ribosome);GO:0005515(protein binding);GO:0019843(rRNA binding);GO:0000027(ribosomal large subunit assembly);GO:0005743(mitochondrial inner membrane);GO:0070125(mitochondrial translational elongation);GO:0070126(mitochondrial translational termination);GO:0005761(mitochondrial ribosome);GO:0005762(mitochondrial large ribosomal subunit)","03010(Ribosome)","K02867","NA","mitochondrial ribosomal protein L11 [Source:HGNC Symbol;Acc:HGNC:14042]",0,0,1,0,1,1,"no","no"]
[162658,0,"chr6","+",7108031,7250012,"ENST00000334984",12,5789,"MSTRG.12653","RREB1","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016607(nuclear speck);GO:0046872(metal ion binding);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0001650(fibrillar center);GO:0045893(positive regulation of transcription, DNA-templated);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0070062(extracellular exosome);GO:0001228(transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0007275(multicellular organism development);GO:0006366(transcription from RNA polymerase II promoter);GO:0000977(RNA polymerase II regulatory region sequence-specific DNA binding);GO:0007265(Ras protein signal transduction);GO:0010634(positive regulation of epithelial cell migration);GO:0016604(nuclear body);GO:0000979(RNA polymerase II core promoter sequence-specific DNA binding);GO:1900026(positive regulation of substrate adhesion-dependent cell spreading);GO:2000394(positive regulation of lamellipodium morphogenesis);GO:0033601(positive regulation of mammary gland epithelial cell proliferation);GO:1903691(positive regulation of wound healing, spreading of epidermal cells);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0045892(negative regulation of transcription, DNA-templated)","NA","NA","NA","ras responsive element binding protein 1 [Source:HGNC Symbol;Acc:HGNC:10449]",{"v":1.324129,"d":"1.32"},0,"inf","inf",1,1,"up","no"]
[39007,0,"chr12","+",12070939,12099695,"ENST00000308721",6,1897,"ENSG00000121380","BCL2L14","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005829(cytosol);GO:0042981(regulation of apoptotic process);GO:0005515(protein binding);GO:0006915(apoptotic process);GO:0019901(protein kinase binding);GO:0012505(endomembrane system);GO:0043229(intracellular organelle)","NA","NA","NA","BCL2 like 14 [Source:HGNC Symbol;Acc:HGNC:16657]",{"v":0.05141,"d":"0.05"},0,"inf","inf",1,1,"up","no"]
[111139,0,"chr2","+",73985132,73986343,"ENST00000441217",2,390,"ENSG00000235499","AC073046.1","NA","NA","NA","NA","NA",{"v":0.426741,"d":"0.43"},{"v":0.526296,"d":"0.53"},{"v":0.810838387523371,"d":"0.81"},{"v":-0.30251370295155,"d":"-0.30"},1,1,"down","no"]
[110596,0,"chr2","-",69963254,70086197,"ENST00000628305",8,1063,"MSTRG.8891","PCBP1-AS1","NA","NA","NA","NA","PCBP1 antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:42948]",0,0,1,0,1,1,"no","no"]
[73327,0,"chr16","+",56643725,56644765,"ENST00000486551",3,150,"ENSG00000205361","MT1DP","NA","NA","NA","NA","metallothionein 1D, pseudogene [Source:HGNC Symbol;Acc:HGNC:7396]",{"v":0.257581,"d":"0.26"},0,"inf","inf",1,1,"up","no"]
[2156,0,"chr1","+",17346034,17348207,"ENST00000468945",2,373,"MSTRG.195","PADI4","GO:0005737(cytoplasm);GO:0005509(calcium ion binding);GO:0004668(protein-arginine deiminase activity);GO:0018101(protein citrullination);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0016787(hydrolase activity);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0016569(covalent chromatin modification);GO:0006334(nucleosome assembly);GO:0005515(protein binding);GO:0002376(immune system process);GO:0045087(innate immune response);GO:0006325(chromatin organization);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0006338(chromatin remodeling);GO:0043234(protein complex);GO:0006464(cellular protein modification process);GO:0042803(protein homodimerization activity);GO:0019827(stem cell population maintenance);GO:0016990(arginine deiminase activity);GO:0034618(arginine binding);GO:0019546(arginine deiminase pathway);GO:0036413(histone H3-R26 citrullination);GO:0036414(histone citrullination)","NA","NA","NA","peptidyl arginine deiminase 4 [Source:HGNC Symbol;Acc:HGNC:18368]",0,{"v":2.401335,"d":"2.40"},"-inf","-inf",1,1,"down","no"]
[80198,0,"chr17","+",18087974,18098464,"ENST00000584212",3,465,"MSTRG.6491","DRG2","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0043231(intracellular membrane-bounded organelle);GO:0005525(GTP binding);GO:0000166(nucleotide binding);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0005515(protein binding);GO:0007165(signal transduction);GO:0005739(mitochondrion)","NA","NA","NA","developmentally regulated GTP binding protein 2 [Source:HGNC Symbol;Acc:HGNC:3030]",{"v":0.392411,"d":"0.39"},0,"inf","inf",1,1,"up","no"]
[34501,0,"chr11","+",101594020,101594934,"ENST00000526526",1,915,"ENSG00000254506","AP003080.1","NA","NA","NA","NA","NA",0,{"v":0.04338,"d":"0.04"},"-inf","-inf",1,1,"down","no"]
[128429,0,"chr22","+",18906238,18947732,"ENST00000638240",6,1669,"ENSG00000283809","AC007326.4","NA","NA","NA","NA","NA",{"v":0.344317,"d":"0.34"},{"v":0.196549,"d":"0.20"},{"v":1.75181252512096,"d":"1.75"},{"v":0.808848389351046,"d":"0.81"},1,1,"up","no"]
[101310,0,"chr19","+",39480853,39488186,"ENST00000601403",7,769,"ENSG00000105197","TIMM50","GO:0003723(RNA binding);GO:0006810(transport);GO:0005634(nucleus);GO:0016607(nuclear speck);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0015031(protein transport);GO:0005654(nucleoplasm);GO:0005739(mitochondrion);GO:0005743(mitochondrial inner membrane);GO:0035335(peptidyl-tyrosine dephosphorylation);GO:0005744(mitochondrial inner membrane presequence translocase complex);GO:0005515(protein binding);GO:0004725(protein tyrosine phosphatase activity);GO:0043021(ribonucleoprotein complex binding);GO:0006470(protein dephosphorylation);GO:0030150(protein import into mitochondrial matrix);GO:0004722(protein serine/threonine phosphatase activity);GO:0007006(mitochondrial membrane organization);GO:0005134(interleukin-2 receptor binding);GO:0004721(phosphoprotein phosphatase activity);GO:0001836(release of cytochrome c from mitochondria)","NA","NA","NA","translocase of inner mitochondrial membrane 50 [Source:HGNC Symbol;Acc:HGNC:23656]",{"v":0.057007,"d":"0.06"},0,"inf","inf",1,1,"up","no"]
[166741,0,"chr6","-",53498142,53501350,"ENST00000515580",2,2132,"ENSG00000001084","GCLC","GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0016874(ligase activity);GO:0000287(magnesium ion binding);GO:0050880(regulation of blood vessel size);GO:0004357(glutamate-cysteine ligase activity);GO:0006750(glutathione biosynthetic process);GO:0005829(cytosol);GO:0043066(negative regulation of apoptotic process);GO:0006979(response to oxidative stress);GO:0045892(negative regulation of transcription, DNA-templated);GO:0045454(cell redox homeostasis);GO:0009408(response to heat);GO:0006536(glutamate metabolic process);GO:0009725(response to hormone);GO:0050662(coenzyme binding);GO:0043531(ADP binding);GO:0016595(glutamate binding);GO:0046982(protein heterodimerization activity);GO:0006534(cysteine metabolic process);GO:0006749(glutathione metabolic process);GO:0007568(aging);GO:0007584(response to nutrient);GO:0008637(apoptotic mitochondrial changes);GO:0009410(response to xenobiotic stimulus);GO:0014823(response to activity);GO:0019852(L-ascorbic acid metabolic process);GO:0031397(negative regulation of protein ubiquitination);GO:0032436(positive regulation of proteasomal ubiquitin-dependent protein catabolic process);GO:0032869(cellular response to insulin stimulus);GO:0035729(cellular response to hepatocyte growth factor stimulus);GO:0043524(negative regulation of neuron apoptotic process);GO:0044344(cellular response to fibroblast growth factor stimulus);GO:0044752(response to human chorionic gonadotropin);GO:0046685(response to arsenic-containing substance);GO:0046686(response to cadmium ion);GO:0051409(response to nitrosative stress);GO:0051900(regulation of mitochondrial depolarization);GO:0070555(response to interleukin-1);GO:0071260(cellular response to mechanical stimulus);GO:0071333(cellular response to glucose stimulus);GO:0071372(cellular response to follicle-stimulating hormone stimulus);GO:0097069(cellular response to thyroxine stimulus);GO:2000490(negative regulation of hepatic stellate cell activation);GO:2001237(negative regulation of extrinsic apoptotic signaling pathway);GO:0017109(glutamate-cysteine ligase complex);GO:0016020(membrane);GO:0016021(integral component of membrane)","00270(Cysteine and methionine metabolism);00480(Glutathione metabolism);04216(Ferroptosis)","NA","NA","glutamate-cysteine ligase catalytic subunit [Source:HGNC Symbol;Acc:HGNC:4311]",0,0,1,0,1,1,"no","no"]
[40744,0,"chr12","-",47663290,47664843,"ENST00000548211",2,555,"MSTRG.3325","RPAP3","GO:0005515(protein binding);GO:0097255(R2TP complex)","NA","NA","NA","RNA polymerase II associated protein 3 [Source:HGNC Symbol;Acc:HGNC:26151]",0,{"v":0.011529,"d":"0.01"},"-inf","-inf",1,1,"down","no"]
[33916,0,"chr11","-",86441108,86672198,"ENST00000393324",14,2240,"ENSG00000151376","ME3","GO:0046872(metal ion binding);GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0005739(mitochondrion);GO:0051287(NAD binding);GO:0048037(cofactor binding);GO:0005759(mitochondrial matrix);GO:0004470(malic enzyme activity);GO:0004471(malate dehydrogenase (decarboxylating) (NAD+) activity);GO:0008948(oxaloacetate decarboxylase activity);GO:0006090(pyruvate metabolic process);GO:0006108(malate metabolic process);GO:0009060(aerobic respiration);GO:0004473(malate dehydrogenase (decarboxylating) (NADP+) activity);GO:0072592(oxygen metabolic process)","00620(Pyruvate metabolism)","K00029","EC:1.1.1.40","malic enzyme 3 [Source:HGNC Symbol;Acc:HGNC:6985]",0,{"v":0.027596,"d":"0.03"},"-inf","-inf",1,1,"down","no"]
[42392,0,"chr12","-",54181485,54187906,"ENST00000505662",3,1422,"ENSG00000123415","SMUG1","GO:0005634(nucleus);GO:0016787(hydrolase activity);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0006281(DNA repair);GO:0006974(cellular response to DNA damage stimulus);GO:0005654(nucleoplasm);GO:0045008(depyrimidination);GO:0005730(nucleolus);GO:0004844(uracil DNA N-glycosylase activity);GO:0006284(base-excision repair);GO:0000703(oxidized pyrimidine nucleobase lesion DNA N-glycosylase activity);GO:0017065(single-strand selective uracil DNA N-glycosylase activity);GO:0019104(DNA N-glycosylase activity)","03410(Base excision repair)","NA","NA","single-strand-selective monofunctional uracil-DNA glycosylase 1 [Source:HGNC Symbol;Acc:HGNC:17148]",{"v":0.015201,"d":"0.02"},0,"inf","inf",1,1,"up","no"]
[176050,0,"chr7","+",92457564,92491610,"ENST00000427458",5,643,"ENSG00000244055","AC007566.1","NA","NA","NA","NA","NA",{"v":0.283496,"d":"0.28"},{"v":0.234386,"d":"0.23"},{"v":1.2095261662386,"d":"1.21"},{"v":0.274441980144072,"d":"0.27"},1,1,"up","no"]
[137195,0,"chr3","-",52813283,52814212,"ENST00000464000",2,446,"ENSG00000055955","ITIH4","GO:0004867(serine-type endopeptidase inhibitor activity);GO:0010951(negative regulation of endopeptidase activity);GO:0005576(extracellular region);GO:0030414(peptidase inhibitor activity);GO:0010466(negative regulation of peptidase activity);GO:0030212(hyaluronan metabolic process);GO:0005515(protein binding);GO:0070062(extracellular exosome);GO:0072562(blood microparticle);GO:0006953(acute-phase response);GO:0002576(platelet degranulation);GO:0004866(endopeptidase inhibitor activity);GO:0034097(response to cytokine);GO:0031089(platelet dense granule lumen);GO:0005737(cytoplasm);GO:0005886(plasma membrane)","NA","NA","NA","inter-alpha-trypsin inhibitor heavy chain family member 4 [Source:HGNC Symbol;Acc:HGNC:6169]",0,0,1,0,1,1,"no","no"]
[40208,0,"chr12","+",31959438,31992941,"ENST00000535596",5,965,"MSTRG.3283","KIAA1551","NA","NA","NA","NA","KIAA1551 [Source:HGNC Symbol;Acc:HGNC:25559]",0,{"v":0.389427,"d":"0.39"},"-inf","-inf",1,1,"down","no"]
[119476,0,"chr2","-",219374880,219381779,"ENST00000488051",3,480,"MSTRG.9440","DNPEP","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0005829(cytosol);GO:0016787(hydrolase activity);GO:0005515(protein binding);GO:0008233(peptidase activity);GO:0006508(proteolysis);GO:0008237(metallopeptidase activity);GO:0004177(aminopeptidase activity);GO:0042802(identical protein binding);GO:0072562(blood microparticle);GO:0070006(metalloaminopeptidase activity);GO:0006518(peptide metabolic process)","NA","NA","NA","aspartyl aminopeptidase [Source:HGNC Symbol;Acc:HGNC:2981]",0,0,1,0,1,1,"no","no"]
[178089,0,"chr7","+",117020227,117137342,"ENST00000465133",7,2155,"ENSG00000004866","ST7","GO:0016020(membrane);GO:0016021(integral component of membrane)","NA","NA","NA","suppression of tumorigenicity 7 [Source:HGNC Symbol;Acc:HGNC:11351]",0,{"v":0.004106,"d":"0.00"},"-inf","-inf",1,1,"down","no"]
[52445,0,"chr14","+",20989994,20996995,"ENST00000555640",10,2887,"ENSG00000165792","METTL17","GO:0008168(methyltransferase activity);GO:0016740(transferase activity);GO:0032259(methylation);GO:0030529(intracellular ribonucleoprotein complex);GO:0006412(translation);GO:0005840(ribosome);GO:0005739(mitochondrion);GO:0005515(protein binding)","NA","NA","NA","methyltransferase like 17 [Source:HGNC Symbol;Acc:HGNC:19280]",0,{"v":0.210319,"d":"0.21"},"-inf","-inf",1,1,"down","no"]
[62892,0,"chr15","+",56919148,57192239,"ENST00000557947",7,575,"ENSG00000140262","TCF12","GO:0005737(cytoplasm);GO:0005634(nucleus);GO:0016607(nuclear speck);GO:0043231(intracellular membrane-bounded organelle);GO:0005654(nucleoplasm);GO:0046983(protein dimerization activity);GO:0006366(transcription from RNA polymerase II promoter);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0007275(multicellular organism development);GO:0007399(nervous system development);GO:0030154(cell differentiation);GO:0035497(cAMP response element binding);GO:0046982(protein heterodimerization activity);GO:0070888(E-box binding);GO:0071837(HMG box domain binding);GO:0010628(positive regulation of gene expression);GO:0045666(positive regulation of neuron differentiation);GO:0045893(positive regulation of transcription, DNA-templated);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0005667(transcription factor complex);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:1902036(regulation of hematopoietic stem cell differentiation);GO:0006955(immune response);GO:0043425(bHLH transcription factor binding);GO:0000790(nuclear chromatin);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0044212(transcription regulatory region DNA binding);GO:0090575(RNA polymerase II transcription factor complex);GO:0001077(transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0007517(muscle organ development);GO:0042803(protein homodimerization activity);GO:0046332(SMAD binding);GO:0008134(transcription factor binding);GO:0035326(enhancer binding)","NA","NA","NA","transcription factor 12 [Source:HGNC Symbol;Acc:HGNC:11623]",0,{"v":0.093804,"d":"0.09"},"-inf","-inf",1,1,"down","no"]
[135777,0,"chr3","-",48120669,48121215,"ENST00000444020",1,547,"ENSG00000236768","AC124916.1","NA","NA","NA","NA","NA",{"v":0.093971,"d":"0.09"},{"v":0.083407,"d":"0.08"},{"v":1.12665603606412,"d":"1.13"},{"v":0.172047133250861,"d":"0.17"},1,1,"up","no"]
[108345,0,"chr2","+",27889941,28025385,"ENST00000436924",6,874,"MSTRG.8592","BABAM2","GO:0005829(cytosol);GO:0070531(BRCA1-A complex);GO:0070552(BRISC complex);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016569(covalent chromatin modification);GO:0051301(cell division);GO:0005515(protein binding);GO:0006281(DNA repair);GO:0006974(cellular response to DNA damage stimulus);GO:0007049(cell cycle);GO:0006915(apoptotic process);GO:0005654(nucleoplasm);GO:0016579(protein deubiquitination);GO:0070536(protein K63-linked deubiquitination);GO:0043066(negative regulation of apoptotic process);GO:0007165(signal transduction);GO:0031572(G2 DNA damage checkpoint);GO:0005164(tumor necrosis factor receptor binding);GO:0045739(positive regulation of DNA repair);GO:0006302(double-strand break repair);GO:0006303(double-strand break repair via nonhomologous end joining);GO:0010212(response to ionizing radiation);GO:0031593(polyubiquitin binding);GO:0000152(nuclear ubiquitin ligase complex);GO:0000268(peroxisome targeting sequence binding)","03440(Homologous recombination)","NA","NA","BRISC and BRCA1 A complex member 2 [Source:HGNC Symbol;Acc:HGNC:1106]",{"v":0.064482,"d":"0.06"},{"v":0.158957,"d":"0.16"},{"v":0.405656875758853,"d":"0.41"},{"v":-1.30166815304243,"d":"-1.30"},1,1,"down","no"]
[118066,0,"chr2","-",201535004,201619178,"ENST00000450242",13,2571,"ENSG00000155754","C2CD6","GO:0005515(protein binding)","NA","NA","NA","C2 calcium dependent domain containing 6 [Source:HGNC Symbol;Acc:HGNC:14438]",0,{"v":0.015675,"d":"0.02"},"-inf","-inf",1,1,"down","no"]
[16233,0,"chr1","-",222564078,222589788,"ENST00000487009",8,959,"ENSG00000143498","TAF1A","GO:0005634(nucleus);GO:0043231(intracellular membrane-bounded organelle);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0015630(microtubule cytoskeleton);GO:0005515(protein binding);GO:0005654(nucleoplasm);GO:0006360(transcription from RNA polymerase I promoter);GO:0045815(positive regulation of gene expression, epigenetic);GO:0006366(transcription from RNA polymerase II promoter);GO:0006361(transcription initiation from RNA polymerase I promoter);GO:0006362(transcription elongation from RNA polymerase I promoter);GO:0006363(termination of RNA polymerase I transcription);GO:0000120(RNA polymerase I transcription factor complex)","NA","NA","NA","TATA-box binding protein associated factor, RNA polymerase I subunit A [Source:HGNC Symbol;Acc:HGNC:11532]",{"v":0.294103,"d":"0.29"},0,"inf","inf",1,1,"up","no"]
[82737,0,"chr17","+",38914397,38916837,"ENST00000579123",2,1874,"MSTRG.6768","LASP1","GO:0005737(cytoplasm);GO:0006810(transport);GO:0046872(metal ion binding);GO:0034220(ion transmembrane transport);GO:0009967(positive regulation of signal transduction);GO:0003779(actin binding);GO:0006811(ion transport);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0015075(ion transmembrane transporter activity);GO:0051015(actin filament binding);GO:0005925(focal adhesion);GO:0030864(cortical actin cytoskeleton);GO:0045296(cadherin binding);GO:0070062(extracellular exosome);GO:0005938(cell cortex);GO:0005070(SH3/SH2 adaptor activity)","NA","NA","NA","LIM and SH3 protein 1 [Source:HGNC Symbol;Acc:HGNC:6513]",{"v":0.004661,"d":"0.00"},{"v":0.221665,"d":"0.22"},{"v":0.0210272257686148,"d":"0.02"},{"v":-5.57159766941863,"d":"-5.57"},1,1,"down","no"]
[71798,0,"chr16","-",30116635,30123150,"ENST00000395200",7,997,"MSTRG.5825","MAPK3","GO:0070374(positive regulation of ERK1 and ERK2 cascade);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0001934(positive regulation of protein phosphorylation);GO:0030509(BMP signaling pathway);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0016740(transferase activity);GO:0004707(MAP kinase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0005794(Golgi apparatus);GO:0005829(cytosol);GO:0005739(mitochondrion);GO:0005886(plasma membrane);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0007049(cell cycle);GO:0006915(apoptotic process);GO:0005901(caveola);GO:0005925(focal adhesion);GO:0038095(Fc-epsilon receptor signaling pathway);GO:0038096(Fc-gamma receptor signaling pathway involved in phagocytosis);GO:0005654(nucleoplasm);GO:0070062(extracellular exosome);GO:0000165(MAPK cascade);GO:0005769(early endosome);GO:0016032(viral process);GO:0005770(late endosome);GO:0019902(phosphatase binding);GO:0001784(phosphotyrosine residue binding);GO:0004708(MAP kinase kinase activity);GO:0097110(scaffold protein binding);GO:0000187(activation of MAPK activity);GO:0000189(MAPK import into nucleus);GO:0002741(positive regulation of cytokine secretion involved in immune response);GO:0006351(transcription, DNA-templated);GO:0006461(protein complex assembly);GO:0006974(cellular response to DNA damage stimulus);GO:0009636(response to toxic substance);GO:0009887(animal organ morphogenesis);GO:0010759(positive regulation of macrophage chemotaxis);GO:0014032(neural crest cell development);GO:0018105(peptidyl-serine phosphorylation);GO:0019233(sensory perception of pain);GO:0019369(arachidonic acid metabolic process);GO:0030278(regulation of ossification);GO:0030641(regulation of cellular pH);GO:0030878(thyroid gland development);GO:0031663(lipopolysaccharide-mediated signaling pathway);GO:0032496(response to lipopolysaccharide);GO:0035556(intracellular signal transduction);GO:0042473(outer ear morphogenesis);GO:0043330(response to exogenous dsRNA);GO:0045727(positive regulation of translation);GO:0045893(positive regulation of transcription, DNA-templated);GO:0048538(thymus development);GO:0051090(regulation of sequence-specific DNA binding transcription factor activity);GO:0051216(cartilage development);GO:0060020(Bergmann glial cell differentiation);GO:0060324(face development);GO:0060425(lung morphogenesis);GO:0060440(trachea formation);GO:0061308(cardiac neural crest cell development involved in heart development);GO:0070371(ERK1 and ERK2 cascade);GO:1904417(positive regulation of xenophagy);GO:1905050(positive regulation of metallopeptidase activity);GO:2000657(negative regulation of apolipoprotein binding);GO:0031143(pseudopodium);GO:0043234(protein complex);GO:0071260(cellular response to mechanical stimulus);GO:0030168(platelet activation);GO:0007411(axon guidance);GO:0014066(regulation of phosphatidylinositol 3-kinase signaling);GO:0032212(positive regulation of telomere maintenance via telomerase);GO:0051973(positive regulation of telomerase activity);GO:1904355(positive regulation of telomere capping);GO:0006975(DNA damage induced protein phosphorylation);GO:0034614(cellular response to reactive oxygen species);GO:0071276(cellular response to cadmium ion);GO:0006361(transcription initiation from RNA polymerase I promoter);GO:0005635(nuclear envelope);GO:1900034(regulation of cellular response to heat);GO:0008543(fibroblast growth factor receptor signaling pathway);GO:0051493(regulation of cytoskeleton organization);GO:0070498(interleukin-1-mediated signaling pathway);GO:0060397(JAK-STAT cascade involved in growth hormone signaling pathway);GO:2000641(regulation of early endosome to late endosome transport);GO:0033129(positive regulation of histone phosphorylation);GO:0035066(positive regulation of histone acetylation);GO:0038083(peptidyl-tyrosine autophosphorylation);GO:0010628(positive regulation of gene expression);GO:1903351(cellular response to dopamine);GO:0070849(response to epidermal growth factor);GO:0034198(cellular response to amino acid starvation);GO:0031281(positive regulation of cyclase activity);GO:0032872(regulation of stress-activated MAPK cascade);GO:0051403(stress-activated MAPK cascade);GO:0072584(caveolin-mediated endocytosis);GO:0090170(regulation of Golgi inheritance);GO:0005622(intracellular)","04014(Ras signaling pathway);04015(Rap1 signaling pathway);04010(MAPK signaling pathway);04012(ErbB signaling pathway);04350(TGF-beta signaling pathway);04370(VEGF signaling pathway);04371(Apelin signaling pathway);04668(TNF signaling pathway);04066(HIF-1 signaling pathway);04068(FoxO signaling pathway);04072(Phospholipase D signaling pathway);04071(Sphingolipid signaling pathway);04024(cAMP signaling pathway);04022(cGMP - PKG signaling pathway);04151(PI3K-Akt signaling pathway);04150(mTOR signaling pathway);04140(Autophagy - animal);04114(Oocyte meiosis);04210(Apoptosis);04218(Cellular senescence);04510(Focal adhesion);04520(Adherens junction);04540(Gap junction);04550(Signaling pathways regulating pluripotency of stem cells);04810(Regulation of actin cytoskeleton);04611(Platelet activation);04620(Toll-like receptor signaling pathway);04621(NOD-like receptor signaling pathway);04650(Natural killer cell mediated cytotoxicity);04660(T cell receptor signaling pathway);04658(Th1 and Th2 cell differentiation);04659(Th17 cell differentiation);04657(IL-17 signaling pathway);04662(B cell receptor signaling pathway);04664(Fc epsilon RI signaling pathway);04666(Fc gamma R-mediated phagocytosis);04062(Chemokine signaling pathway);04910(Insulin signaling pathway);04912(GnRH signaling pathway);04915(Estrogen signaling pathway);04914(Progesterone-mediated oocyte maturation);04917(Prolactin signaling pathway);04921(Oxytocin signaling pathway);04926(Relaxin signaling pathway);04919(Thyroid hormone signaling pathway);04916(Melanogenesis);04261(Adrenergic signaling in cardiomyocytes);04270(Vascular smooth muscle contraction);04960(Aldosterone-regulated sodium reabsorption);04724(Glutamatergic synapse);04725(Cholinergic synapse);04726(Serotonergic synapse);04720(Long-term potentiation);04730(Long-term depression);04723(Retrograde endocannabinoid signaling);04722(Neurotrophin signaling pathway);04360(Axon guidance);04380(Osteoclast differentiation);04713(Circadian entrainment);05200(Pathways in cancer);05230(Central carbon metabolism in cancer);05231(Choline metabolism in cancer);05205(Proteoglycans in cancer);05203(Viral carcinogenesis);05210(Colorectal cancer);05212(Pancreatic cancer);05225(Hepatocellular carcinoma);05226(Gastric cancer);05214(Glioma);05216(Thyroid cancer);05221(Acute myeloid leukemia);05220(Chronic myeloid leukemia);05218(Melanoma);05211(Renal cell carcinoma);05219(Bladder cancer);05215(Prostate cancer);05213(Endometrial cancer);05224(Breast cancer);05223(Non-small cell lung cancer);05010(Alzheimer's disease);05020(Prion diseases);05034(Alcoholism);04930(Type II diabetes mellitus);04933(AGE-RAGE signaling pathway in diabetic complications);05132(Salmonella infection);05131(Shigellosis);05133(Pertussis);05152(Tuberculosis);05164(Influenza A);05161(Hepatitis B);05160(Hepatitis C);05167(Kaposi's sarcoma-associated herpesvirus infection);05165(Human papillomavirus infection);05145(Toxoplasmosis);05140(Leishmaniasis);05142(Chagas disease (American trypanosomiasis));01521(EGFR tyrosine kinase inhibitor resistance);01524(Platinum drug resistance);01522(Endocrine resistance)","NA","NA","mitogen-activated protein kinase 3 [Source:HGNC Symbol;Acc:HGNC:6877]",0,{"v":0.402741,"d":"0.40"},"-inf","-inf",1,1,"down","no"]
[13507,0,"chr1","+",169795043,169807837,"ENST00000481744",7,755,"MSTRG.1186","C1orf112","NA","NA","NA","NA","chromosome 1 open reading frame 112 [Source:HGNC Symbol;Acc:HGNC:25565]",0,{"v":0.022784,"d":"0.02"},"-inf","-inf",1,1,"down","no"]
[102824,0,"chr19","+",45522789,45524413,"ENST00000588463",3,655,"MSTRG.8230","VASP","GO:0008154(actin polymerization or depolymerization);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005829(cytosol);GO:0003779(actin binding);GO:0005886(plasma membrane);GO:0005925(focal adhesion);GO:0017124(SH3 domain binding);GO:0001843(neural tube closure);GO:0007411(axon guidance);GO:0030036(actin cytoskeleton organization);GO:0051289(protein homotetramerization);GO:0005856(cytoskeleton);GO:0030027(lamellipodium);GO:0030175(filopodium);GO:0042995(cell projection);GO:0005515(protein binding);GO:0030054(cell junction);GO:0005923(bicellular tight junction);GO:0045296(cadherin binding);GO:0070062(extracellular exosome);GO:0015629(actin cytoskeleton);GO:0030838(positive regulation of actin filament polymerization);GO:0031527(filopodium membrane);GO:0031258(lamellipodium membrane);GO:0034329(cell junction assembly);GO:0005522(profilin binding)","04015(Rap1 signaling pathway);04022(cGMP - PKG signaling pathway);04510(Focal adhesion);04530(Tight junction);04611(Platelet activation);04666(Fc gamma R-mediated phagocytosis);04670(Leukocyte transendothelial migration)","NA","NA","vasodilator stimulated phosphoprotein [Source:HGNC Symbol;Acc:HGNC:12652]",{"v":1.007782,"d":"1.01"},{"v":0.904869,"d":"0.90"},{"v":1.11373248503375,"d":"1.11"},{"v":0.155402743573326,"d":"0.16"},1,1,"up","no"]
[45391,0,"chr12","-",95516560,95551490,"ENST00000258499",6,4022,"ENSG00000136014","USP44","GO:0005634(nucleus);GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0016579(protein deubiquitination);GO:0016787(hydrolase activity);GO:0051301(cell division);GO:0008233(peptidase activity);GO:0008234(cysteine-type peptidase activity);GO:0006508(proteolysis);GO:0007049(cell cycle);GO:0006511(ubiquitin-dependent protein catabolic process);GO:0036459(thiol-dependent ubiquitinyl hydrolase activity);GO:0005515(protein binding);GO:0005654(nucleoplasm);GO:0004843(thiol-dependent ubiquitin-specific protease activity);GO:0043161(proteasome-mediated ubiquitin-dependent protein catabolic process);GO:0090266(regulation of mitotic cell cycle spindle assembly checkpoint);GO:1904667(negative regulation of ubiquitin protein ligase activity)","NA","NA","NA","ubiquitin specific peptidase 44 [Source:HGNC Symbol;Acc:HGNC:20064]",{"v":0.281889,"d":"0.28"},{"v":0.051613,"d":"0.05"},{"v":5.46158913452037,"d":"5.46"},{"v":2.44932078684482,"d":"2.45"},1,1,"up","no"]
[98421,0,"chr19","+",17754218,17762805,"ENST00000598960",4,534,"MSTRG.7982","FCHO1","GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0072583(clathrin-dependent endocytosis);GO:0016020(membrane);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0005905(clathrin-coated pit);GO:0006897(endocytosis);GO:0061024(membrane organization);GO:0048268(clathrin coat assembly);GO:0035612(AP-2 adaptor complex binding)","NA","NA","NA","FCH domain only 1 [Source:HGNC Symbol;Acc:HGNC:29002]",0,0,1,0,1,1,"no","no"]
[2941,0,"chr1","+",25818640,25829514,"ENST00000424294",6,756,"MSTRG.273","MTFR1L","GO:0005515(protein binding);GO:0009060(aerobic respiration);GO:0005739(mitochondrion);GO:0000266(mitochondrial fission)","NA","NA","NA","mitochondrial fission regulator 1 like [Source:HGNC Symbol;Acc:HGNC:28836]",0,{"v":1.34E-4,"d":"0.00"},"-inf","-inf",1,1,"down","no"]
[75199,0,"chr16","-",70375978,70400638,"ENST00000393640",6,8872,"MSTRG.6095","ST3GAL2","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016740(transferase activity);GO:0003836(beta-galactoside (CMP) alpha-2,3-sialyltransferase activity);GO:0008373(sialyltransferase activity);GO:0016757(transferase activity, transferring glycosyl groups);GO:0006486(protein glycosylation);GO:0097503(sialylation);GO:0005794(Golgi apparatus);GO:0005576(extracellular region);GO:0032580(Golgi cisterna membrane);GO:0006464(cellular protein modification process);GO:0000139(Golgi membrane);GO:0016266(O-glycan processing);GO:0018146(keratan sulfate biosynthetic process);GO:0009311(oligosaccharide metabolic process);GO:0018279(protein N-linked glycosylation via asparagine);GO:0006040(amino sugar metabolic process)","00512(Mucin type O-glycan biosynthesis);00533(Glycosaminoglycan biosynthesis - keratan sulfate);00603(Glycosphingolipid biosynthesis - globo and isoglobo series);00604(Glycosphingolipid biosynthesis - ganglio series)","NA","NA","ST3 beta-galactoside alpha-2,3-sialyltransferase 2 [Source:HGNC Symbol;Acc:HGNC:10863]",{"v":0.011587,"d":"0.01"},{"v":0.004577,"d":"0.00"},{"v":2.5315708979681,"d":"2.53"},{"v":1.34003288824327,"d":"1.34"},1,1,"up","no"]
[192759,0,"chr9","-",113386319,113401243,"ENST00000482847",12,3247,"MSTRG.14917","ALAD","GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0003824(catalytic activity);GO:0016829(lyase activity);GO:0008270(zinc ion binding);GO:0008152(metabolic process);GO:0006783(heme biosynthetic process);GO:0005576(extracellular region);GO:0033014(tetrapyrrole biosynthetic process);GO:0004655(porphobilinogen synthase activity);GO:0042802(identical protein binding);GO:1904854(proteasome core complex binding);GO:0001666(response to hypoxia);GO:0006779(porphyrin-containing compound biosynthetic process);GO:0006979(response to oxidative stress);GO:0007584(response to nutrient);GO:0009635(response to herbicide);GO:0009636(response to toxic substance);GO:0009725(response to hormone);GO:0010033(response to organic substance);GO:0010035(response to inorganic substance);GO:0010038(response to metal ion);GO:0010039(response to iron ion);GO:0010043(response to zinc ion);GO:0010044(response to aluminum ion);GO:0010212(response to ionizing radiation);GO:0010266(response to vitamin B1);GO:0010269(response to selenium ion);GO:0010288(response to lead ion);GO:0014070(response to organic cyclic compound);GO:0014823(response to activity);GO:0031667(response to nutrient levels);GO:0032025(response to cobalt ion);GO:0032496(response to lipopolysaccharide);GO:0033197(response to vitamin E);GO:0033273(response to vitamin);GO:0042493(response to drug);GO:0043200(response to amino acid);GO:0045471(response to ethanol);GO:0046685(response to arsenic-containing substance);GO:0046686(response to cadmium ion);GO:0046689(response to mercury ion);GO:0051384(response to glucocorticoid);GO:0051597(response to methylmercury);GO:0070541(response to platinum ion);GO:0070542(response to fatty acid);GO:0071284(cellular response to lead ion);GO:0071353(cellular response to interleukin-4);GO:0005615(extracellular space);GO:0005829(cytosol);GO:0005839(proteasome core complex);GO:0006782(protoporphyrinogen IX biosynthetic process);GO:0070062(extracellular exosome);GO:0043312(neutrophil degranulation);GO:0034774(secretory granule lumen);GO:1904813(ficolin-1-rich granule lumen);GO:0051260(protein homooligomerization);GO:1901799(negative regulation of proteasomal protein catabolic process)","00860(Porphyrin and chlorophyll metabolism)","NA","NA","aminolevulinate dehydratase [Source:HGNC Symbol;Acc:HGNC:395]",{"v":0.092963,"d":"0.09"},0,"inf","inf",1,1,"up","no"]
[6006,0,"chr1","+",51729857,51756369,"ENST00000481937",7,630,"MSTRG.557","OSBPL9","GO:0006810(transport);GO:0016020(membrane);GO:0005794(Golgi apparatus);GO:0043231(intracellular membrane-bounded organelle);GO:0005829(cytosol);GO:0006869(lipid transport);GO:0008289(lipid binding);GO:0005768(endosome);GO:0031902(late endosome membrane);GO:0006699(bile acid biosynthetic process);GO:0015248(sterol transporter activity);GO:0015918(sterol transport)","NA","NA","NA","oxysterol binding protein like 9 [Source:HGNC Symbol;Acc:HGNC:16386]",0,0,1,0,1,1,"no","no"]
[171702,0,"chr7","+",6577505,6589374,"ENST00000396706",8,1942,"MSTRG.13485","ZDHHC4","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016740(transferase activity);GO:0005794(Golgi apparatus);GO:0016746(transferase activity, transferring acyl groups);GO:0019706(protein-cysteine S-palmitoyltransferase activity)","NA","NA","NA","zinc finger DHHC-type containing 4 [Source:HGNC Symbol;Acc:HGNC:18471]",0,{"v":1.261584,"d":"1.26"},"-inf","-inf",1,1,"down","no"]
[60622,0,"chr15","+",32602121,32602411,"ENST00000616519",1,291,"ENSG00000277464","RN7SL286P","NA","NA","NA","NA","RNA, 7SL, cytoplasmic 286, pseudogene [Source:HGNC Symbol;Acc:HGNC:46302]",0,0,1,0,1,1,"no","no"]
[104213,0,"chr19","+",49878187,49885534,"ENST00000599049",13,1742,"MSTRG.8352","TBC1D17","GO:0006810(transport);GO:0015031(protein transport);GO:0005829(cytosol);GO:0005515(protein binding);GO:0006914(autophagy);GO:0031410(cytoplasmic vesicle);GO:0005096(GTPase activator activity);GO:0017137(Rab GTPase binding);GO:0006886(intracellular protein transport);GO:0031338(regulation of vesicle fusion);GO:0090630(activation of GTPase activity);GO:0012505(endomembrane system);GO:0061024(membrane organization);GO:0042147(retrograde transport, endosome to Golgi);GO:0005776(autophagosome);GO:0055037(recycling endosome)","04137(Mitophagy - animal)","K19945","NA","TBC1 domain family member 17 [Source:HGNC Symbol;Acc:HGNC:25699]",{"v":11.554898,"d":"11.55"},{"v":0.005547,"d":"0.01"},{"v":2083.08959798089,"d":"2083.09"},{"v":11.0245091786651,"d":"11.02"},1,1,"up","no"]
[194113,0,"chr9","-",129636892,129642124,"ENST00000277459",5,2180,"ENSG00000148331","ASB6","GO:0005737(cytoplasm);GO:0016567(protein ubiquitination);GO:0035556(intracellular signal transduction);GO:0005515(protein binding);GO:0005829(cytosol);GO:0043687(post-translational protein modification);GO:0005622(intracellular)","NA","NA","NA","ankyrin repeat and SOCS box containing 6 [Source:HGNC Symbol;Acc:HGNC:17181]",{"v":0.664543,"d":"0.66"},0,"inf","inf",1,1,"up","no"]
[120821,0,"chr2","-",239969452,240011676,"ENST00000444548",5,621,"MSTRG.9512","NDUFA10","GO:0055114(oxidation-reduction process);GO:0005739(mitochondrion);GO:0005747(mitochondrial respiratory chain complex I);GO:0008137(NADH dehydrogenase (ubiquinone) activity);GO:0006120(mitochondrial electron transport, NADH to ubiquinone);GO:0005759(mitochondrial matrix);GO:0043209(myelin sheath);GO:0070469(respiratory chain);GO:0032981(mitochondrial respiratory chain complex I assembly);GO:0005743(mitochondrial inner membrane)","00190(Oxidative phosphorylation);04723(Retrograde endocannabinoid signaling);05010(Alzheimer's disease);05012(Parkinson's disease);05016(Huntington's disease);04932(Non-alcoholic fatty liver disease (NAFLD))","NA","NA","NADH:ubiquinone oxidoreductase subunit A10 [Source:HGNC Symbol;Acc:HGNC:7684]",0,0,1,0,1,1,"no","no"]
[83090,0,"chr17","+",40219790,40278231,"ENST00000583130",8,1529,"MSTRG.6794","WIPF2","GO:0005737(cytoplasm);GO:0003779(actin binding);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0038096(Fc-gamma receptor signaling pathway involved in phagocytosis);GO:0005829(cytosol)","04144(Endocytosis)","K19475","NA","WAS/WASL interacting protein family member 2 [Source:HGNC Symbol;Acc:HGNC:30923]",0,{"v":3.742071,"d":"3.74"},"-inf","-inf",1,1,"down","no"]
[156637,0,"chr5","+",90474864,90514552,"ENST00000399107",8,3285,"ENSG00000113356","POLR3G","GO:0003899(DNA-directed 5'-3' RNA polymerase activity);GO:0006383(transcription from RNA polymerase III promoter);GO:0005634(nucleus);GO:0002376(immune system process);GO:0045087(innate immune response);GO:0051607(defense response to virus);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0008283(cell proliferation);GO:0032728(positive regulation of interferon-beta production);GO:0045089(positive regulation of innate immune response);GO:0032481(positive regulation of type I interferon production);GO:0005666(DNA-directed RNA polymerase III complex);GO:0000790(nuclear chromatin);GO:0006359(regulation of transcription from RNA polymerase III promoter)","00230(Purine metabolism);00240(Pyrimidine metabolism);03020(RNA polymerase);04623(Cytosolic DNA-sensing pathway);05169(Epstein-Barr virus infection)","K03024","NA","RNA polymerase III subunit G [Source:HGNC Symbol;Acc:HGNC:30075]",{"v":0.462567,"d":"0.46"},0,"inf","inf",1,1,"up","no"]
[129386,0,"chr22","-",23765834,23767942,"ENST00000401675",4,691,"ENSG00000250479","CHCHD10","GO:0005739(mitochondrion);GO:0003674(molecular_function);GO:0005634(nucleus);GO:0005758(mitochondrial intermembrane space);GO:0007005(mitochondrion organization);GO:0006119(oxidative phosphorylation);GO:0006754(ATP biosynthetic process);GO:2000984(negative regulation of ATP citrate synthase activity)","NA","NA","NA","coiled-coil-helix-coiled-coil-helix domain containing 10 [Source:HGNC Symbol;Acc:HGNC:15559]",{"v":0.662192,"d":"0.66"},{"v":0.071224,"d":"0.07"},{"v":9.2973155116253,"d":"9.30"},{"v":3.21681421545313,"d":"3.22"},1,1,"up","no"]
[81153,0,"chr17","-",28364268,28365244,"ENST00000536498",3,666,"MSTRG.6551","SEBOX","GO:0005634(nucleus);GO:0003677(DNA binding);GO:0009792(embryo development ending in birth or egg hatching);GO:0048477(oogenesis)","NA","NA","NA","SEBOX homeobox [Source:HGNC Symbol;Acc:HGNC:32942]",{"v":0.08062,"d":"0.08"},{"v":0.044681,"d":"0.04"},{"v":1.80434636646449,"d":"1.80"},{"v":0.851476308225053,"d":"0.85"},1,1,"up","no"]
[5178,0,"chr1","+",43970008,43972721,"ENST00000524776",5,1596,"ENSG00000132768","DPH2","GO:0016740(transferase activity);GO:0005515(protein binding);GO:0005829(cytosol);GO:0017183(peptidyl-diphthamide biosynthetic process from peptidyl-histidine);GO:0090560(2-(3-amino-3-carboxypropyl)histidine synthase activity)","NA","NA","NA","DPH2 homolog [Source:HGNC Symbol;Acc:HGNC:3004]",0,0,1,0,1,1,"no","no"]
[84593,0,"chr17","-",46032165,46033512,"ENST00000573682",3,358,"MSTRG.6930","KANSL1","GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0016569(covalent chromatin modification);GO:0005694(chromosome);GO:0005515(protein binding);GO:0000123(histone acetyltransferase complex);GO:0000775(chromosome, centromeric region);GO:0000776(kinetochore);GO:0000777(condensed chromosome kinetochore);GO:0071339(MLL1 complex);GO:0043995(histone acetyltransferase activity (H4-K5 specific));GO:0043996(histone acetyltransferase activity (H4-K8 specific));GO:0046972(histone acetyltransferase activity (H4-K16 specific));GO:0043981(histone H4-K5 acetylation);GO:0043982(histone H4-K8 acetylation);GO:0043984(histone H4-K16 acetylation)","NA","NA","NA","KAT8 regulatory NSL complex subunit 1 [Source:HGNC Symbol;Acc:HGNC:24565]",0,{"v":0.153201,"d":"0.15"},"-inf","-inf",1,1,"down","no"]
[194721,0,"chr9","-",135865248,135881718,"ENST00000468150",3,284,"ENSG00000130559","CAMSAP1","GO:0005737(cytoplasm);GO:0005856(cytoskeleton);GO:0031175(neuron projection development);GO:0008017(microtubule binding);GO:0005874(microtubule);GO:0005516(calmodulin binding);GO:0007010(cytoskeleton organization);GO:0022604(regulation of cell morphogenesis);GO:0030507(spectrin binding)","NA","NA","NA","calmodulin regulated spectrin associated protein 1 [Source:HGNC Symbol;Acc:HGNC:19946]",0,0,1,0,1,1,"no","no"]
[194099,0,"chr9","+",129608884,129635930,"ENST00000372486",4,1487,"ENSG00000148335","NTMT1","GO:0005634(nucleus);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0008168(methyltransferase activity);GO:0016740(transferase activity);GO:0032259(methylation);GO:0006480(N-terminal protein amino acid methylation);GO:0005737(cytoplasm);GO:0007059(chromosome segregation);GO:0007051(spindle organization);GO:0042054(histone methyltransferase activity);GO:0016571(histone methylation);GO:0008276(protein methyltransferase activity);GO:0071885(N-terminal protein N-methyltransferase activity);GO:0018011(N-terminal peptidyl-alanine methylation);GO:0018013(N-terminal peptidyl-glycine methylation);GO:0018016(N-terminal peptidyl-proline dimethylation);GO:0035572(N-terminal peptidyl-serine dimethylation);GO:0035573(N-terminal peptidyl-serine trimethylation);GO:0018012(N-terminal peptidyl-alanine trimethylation)","NA","NA","NA","N-terminal Xaa-Pro-Lys N-methyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:23373]",0,0,1,0,1,1,"no","no"]
[58961,0,"chr14","+",102933574,102937177,"ENST00000560931",2,828,"ENSG00000259515","AL117209.1","NA","NA","NA","NA","NA",0,0,1,0,1,1,"no","no"]
[41695,0,"chr12","-",51245745,51270284,"ENST00000605627",5,577,"MSTRG.3376","SMAGP","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005654(nucleoplasm);GO:0005886(plasma membrane);GO:0030054(cell junction);GO:0005515(protein binding);GO:0030659(cytoplasmic vesicle membrane);GO:0031410(cytoplasmic vesicle);GO:0005887(integral component of plasma membrane);GO:0004872(receptor activity);GO:0005102(receptor binding);GO:0042803(protein homodimerization activity);GO:0050839(cell adhesion molecule binding);GO:0007156(homophilic cell adhesion via plasma membrane adhesion molecules);GO:0007157(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules);GO:0005913(cell-cell adherens junction);GO:0008037(cell recognition)","NA","NA","NA","small cell adhesion glycoprotein [Source:HGNC Symbol;Acc:HGNC:26918]",0,{"v":0.000536,"d":"0.00"},"-inf","-inf",1,1,"down","no"]
[38278,0,"chr12","+",7108052,7111606,"ENST00000435921",3,572,"MSTRG.3088","C1RL-AS1","NA","NA","NA","NA","C1RL antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:27461]",{"v":0.156847,"d":"0.16"},{"v":0.094448,"d":"0.09"},{"v":1.66067042181941,"d":"1.66"},{"v":0.731765783122219,"d":"0.73"},1,1,"up","no"]
[73058,0,"chr16","-",53491648,53493968,"ENST00000571523",1,2321,"MSTRG.5929","AKTIP","GO:0006810(transport);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0015031(protein transport);GO:0005829(cytosol);GO:0016567(protein ubiquitination);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0006915(apoptotic process);GO:0031625(ubiquitin protein ligase binding);GO:0061630(ubiquitin protein ligase activity);GO:0008333(endosome to lysosome transport);GO:0007040(lysosome organization);GO:0007032(endosome organization);GO:0001934(positive regulation of protein phosphorylation);GO:0032092(positive regulation of protein binding);GO:0045022(early endosome to late endosome transport);GO:0030897(HOPS complex);GO:0070695(FHF complex)","NA","NA","NA","AKT interacting protein [Source:HGNC Symbol;Acc:HGNC:16710]",{"v":0.2191,"d":"0.22"},{"v":0.080138,"d":"0.08"},{"v":2.7340337917093,"d":"2.73"},{"v":1.45103107426444,"d":"1.45"},1,1,"up","no"]
[37622,0,"chr12","+",4562210,4591160,"ENST00000539701",7,945,"ENSG00000010219","DYRK4","GO:0043231(intracellular membrane-bounded organelle);GO:0004672(protein kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0004674(protein serine/threonine kinase activity);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0004713(protein tyrosine kinase activity);GO:0018108(peptidyl-tyrosine phosphorylation);GO:0005515(protein binding);GO:0004712(protein serine/threonine/tyrosine kinase activity)","NA","NA","NA","dual specificity tyrosine phosphorylation regulated kinase 4 [Source:HGNC Symbol;Acc:HGNC:3095]",0,0,1,0,1,1,"no","no"]
[81911,0,"chr17","+",32051030,32053208,"ENST00000625123",1,2179,"ENSG00000278867","AC090616.7","NA","NA","NA","NA","NA",0,{"v":0.239496,"d":"0.24"},"-inf","-inf",1,1,"down","no"]
[193725,0,"chr9","-",128166066,128191939,"ENST00000538431",18,2996,"MSTRG.14997","CIZ1","GO:0005634(nucleus);GO:0003676(nucleic acid binding);GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0005654(nucleoplasm);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0030332(cyclin binding);GO:0032298(positive regulation of DNA-dependent DNA replication initiation);GO:0051457(maintenance of protein location in nucleus)","NA","NA","NA","CDKN1A interacting zinc finger protein 1 [Source:HGNC Symbol;Acc:HGNC:16744]",{"v":0.029203,"d":"0.03"},{"v":0.152313,"d":"0.15"},{"v":0.191730187180346,"d":"0.19"},{"v":-2.38285059321389,"d":"-2.38"},1,1,"down","no"]
[90313,0,"chr18","+",3448499,3457839,"ENST00000549780",3,801,"ENSG00000177426","TGIF1","GO:0005634(nucleus);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0005654(nucleoplasm);GO:0006351(transcription, DNA-templated);GO:0005515(protein binding);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:0001078(transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0007275(multicellular organism development);GO:0003714(transcription corepressor activity);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0070410(co-SMAD binding);GO:0010629(negative regulation of gene expression);GO:0042493(response to drug);GO:0071363(cellular response to growth factor stimulus)","04350(TGF-beta signaling pathway)","K19383","NA","TGFB induced factor homeobox 1 [Source:HGNC Symbol;Acc:HGNC:11776]",{"v":0.01369,"d":"0.01"},{"v":0.293496,"d":"0.29"},{"v":0.0466445880011993,"d":"0.05"},{"v":-4.42214648955026,"d":"-4.42"},1,1,"down","no"]
[54903,0,"chr14","-",50727233,50766795,"ENST00000530853",18,5068,"MSTRG.4381","NIN","GO:0005509(calcium ion binding);GO:0005813(centrosome);GO:0034454(microtubule anchoring at centrosome);GO:0005737(cytoplasm);GO:0000166(nucleotide binding);GO:0005634(nucleus);GO:0005730(nucleolus);GO:0005525(GTP binding);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0005874(microtubule);GO:0005815(microtubule organizing center);GO:0005814(centriole);GO:0097539(ciliary transition fiber);GO:0000922(spindle pole);GO:0000242(pericentriolar material);GO:0051642(centrosome localization);GO:0090222(centrosome-templated microtubule nucleation);GO:0036449(microtubule minus-end);GO:0097431(mitotic spindle pole)","NA","NA","NA","ninein [Source:HGNC Symbol;Acc:HGNC:14906]",{"v":0.052281,"d":"0.05"},{"v":0.324107,"d":"0.32"},{"v":0.161307839694916,"d":"0.16"},{"v":-2.63211153851329,"d":"-2.63"},1,1,"down","no"]
[180170,0,"chr7","+",151028467,151037570,"ENST00000477092",10,1596,"ENSG00000197150","ABCB8","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0055085(transmembrane transport);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0005634(nucleus);GO:0005730(nucleolus);GO:0005739(mitochondrion);GO:0005743(mitochondrial inner membrane);GO:0042626(ATPase activity, coupled to transmembrane movement of substances);GO:0016887(ATPase activity);GO:0005215(transporter activity);GO:0005740(mitochondrial envelope);GO:0043190(ATP-binding cassette (ABC) transporter complex)","02010(ABC transporters)","NA","NA","ATP binding cassette subfamily B member 8 [Source:HGNC Symbol;Acc:HGNC:49]",{"v":0.108525,"d":"0.11"},0,"inf","inf",1,1,"up","no"]
[53131,0,"chr14","-",23026297,23034885,"ENST00000334454",3,796,"MSTRG.4180","PSMB5","GO:0004175(endopeptidase activity);GO:0004298(threonine-type endopeptidase activity);GO:0051603(proteolysis involved in cellular protein catabolic process);GO:0005839(proteasome core complex);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005654(nucleoplasm);GO:0016787(hydrolase activity);GO:0005813(centrosome);GO:0005515(protein binding);GO:0008233(peptidase activity);GO:0006508(proteolysis);GO:0000502(proteasome complex);GO:0038095(Fc-epsilon receptor signaling pathway);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0000165(MAPK cascade);GO:0000209(protein polyubiquitination);GO:0002223(stimulatory C-type lectin receptor signaling pathway);GO:0002479(antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent);GO:0006521(regulation of cellular amino acid metabolic process);GO:0010972(negative regulation of G2/M transition of mitotic cell cycle);GO:0016579(protein deubiquitination);GO:0031145(anaphase-promoting complex-dependent catabolic process);GO:0031146(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process);GO:0033209(tumor necrosis factor-mediated signaling pathway);GO:0038061(NIK/NF-kappaB signaling);GO:0043161(proteasome-mediated ubiquitin-dependent protein catabolic process);GO:0043488(regulation of mRNA stability);GO:0043687(post-translational protein modification);GO:0050852(T cell receptor signaling pathway);GO:0051437(positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition);GO:0055085(transmembrane transport);GO:0060071(Wnt signaling pathway, planar cell polarity pathway);GO:0061418(regulation of transcription from RNA polymerase II promoter in response to hypoxia);GO:0090090(negative regulation of canonical Wnt signaling pathway);GO:0090263(positive regulation of canonical Wnt signaling pathway);GO:1902036(regulation of hematopoietic stem cell differentiation);GO:0019774(proteasome core complex, beta-subunit complex);GO:0016032(viral process);GO:0051436(negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle);GO:0006979(response to oxidative stress)","03050(Proteasome)","NA","NA","proteasome subunit beta 5 [Source:HGNC Symbol;Acc:HGNC:9542]",{"v":0.000423,"d":"0.00"},0,"inf","inf",1,1,"up","no"]
[158364,0,"chr5","-",133972726,133981017,"ENST00000492324",4,635,"MSTRG.12311","VDAC1","GO:0006810(transport);GO:0005634(nucleus);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0055085(transmembrane transport);GO:0008308(voltage-gated anion channel activity);GO:0098656(anion transmembrane transport);GO:1903959(regulation of anion transmembrane transport);GO:0005741(mitochondrial outer membrane);GO:0005739(mitochondrion);GO:0006811(ion transport);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0006915(apoptotic process);GO:0045121(membrane raft);GO:0006820(anion transport);GO:0070062(extracellular exosome);GO:0044325(ion channel binding);GO:0016032(viral process);GO:1903146(regulation of mitophagy);GO:0030855(epithelial cell differentiation);GO:0042645(mitochondrial nucleoid);GO:0015288(porin activity);GO:0016236(macroautophagy);GO:0019901(protein kinase binding);GO:0046930(pore complex);GO:0005253(anion channel activity);GO:0032403(protein complex binding);GO:0001662(behavioral fear response);GO:0006851(mitochondrial calcium ion transmembrane transport);GO:0007268(chemical synaptic transmission);GO:0007270(neuron-neuron synaptic transmission);GO:0007612(learning);GO:2000378(negative regulation of reactive oxygen species metabolic process);GO:0005743(mitochondrial inner membrane);GO:0008021(synaptic vesicle);GO:0043209(myelin sheath);GO:0043234(protein complex)","04020(Calcium signaling pathway);04022(cGMP - PKG signaling pathway);04217(Necroptosis);04218(Cellular senescence);04621(NOD-like receptor signaling pathway);04979(Cholesterol metabolism);05012(Parkinson's disease);05016(Huntington's disease);05166(HTLV-I infection);05164(Influenza A)","NA","NA","voltage dependent anion channel 1 [Source:HGNC Symbol;Acc:HGNC:12669]",{"v":0.063273,"d":"0.06"},{"v":0.133062,"d":"0.13"},{"v":0.475515173377824,"d":"0.48"},{"v":-1.07243671761292,"d":"-1.07"},1,1,"down","no"]
[145458,0,"chr4","+",2914705,2926137,"ENST00000539149",2,460,"MSTRG.11508","ADD1","GO:0005856(cytoskeleton);GO:0005634(nucleus);GO:0030036(actin cytoskeleton organization);GO:0003723(RNA binding);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005654(nucleoplasm);GO:0003779(actin binding);GO:0005886(plasma membrane);GO:0016604(nuclear body);GO:0005925(focal adhesion);GO:0005516(calmodulin binding);GO:0005829(cytosol);GO:0045296(cadherin binding);GO:0055085(transmembrane transport);GO:0042803(protein homodimerization activity);GO:0046982(protein heterodimerization activity);GO:0036498(IRE1-mediated unfolded protein response);GO:0032092(positive regulation of protein binding);GO:0008134(transcription factor binding);GO:0051015(actin filament binding);GO:0030507(spectrin binding);GO:0005913(cell-cell adherens junction);GO:0051016(barbed-end actin filament capping);GO:0051017(actin filament bundle assembly);GO:0071277(cellular response to calcium ion);GO:1903142(positive regulation of establishment of endothelial barrier);GO:1903393(positive regulation of adherens junction organization);GO:0008290(F-actin capping protein complex);GO:0005198(structural molecule activity);GO:0000902(cell morphogenesis);GO:0001701(in utero embryonic development);GO:0006884(cell volume homeostasis);GO:0020027(hemoglobin metabolic process);GO:0030218(erythrocyte differentiation);GO:0035264(multicellular organism growth);GO:0048873(homeostasis of number of cells within a tissue)","NA","NA","NA","adducin 1 [Source:HGNC Symbol;Acc:HGNC:243]",{"v":0.424115,"d":"0.42"},{"v":0.3038,"d":"0.30"},{"v":1.39603357472021,"d":"1.40"},{"v":0.481333638897044,"d":"0.48"},1,1,"up","no"]
[132032,0,"chr22","+",43986344,43996529,"ENST00000494795",3,3248,"MSTRG.10558","SAMM50","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005739(mitochondrion);GO:0005515(protein binding);GO:0005741(mitochondrial outer membrane);GO:0070062(extracellular exosome);GO:0042407(cristae formation);GO:0045040(protein import into mitochondrial outer membrane);GO:0033108(mitochondrial respiratory chain complex assembly);GO:0001401(mitochondrial sorting and assembly machinery complex);GO:0005743(mitochondrial inner membrane);GO:0019867(outer membrane)","NA","NA","NA","SAMM50 sorting and assembly machinery component [Source:HGNC Symbol;Acc:HGNC:24276]",{"v":0.281953,"d":"0.28"},{"v":0.066809,"d":"0.07"},{"v":4.22028469218219,"d":"4.22"},{"v":2.07734032361156,"d":"2.08"},1,1,"up","no"]
[55851,0,"chr14","+",64440221,64445138,"ENST00000556771",5,813,"MSTRG.4467","MTHFD1","GO:0005524(ATP binding);GO:0005829(cytosol);GO:0055114(oxidation-reduction process);GO:0003824(catalytic activity);GO:0004488(methylenetetrahydrofolate dehydrogenase (NADP+) activity);GO:0004329(formate-tetrahydrofolate ligase activity);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0000166(nucleotide binding);GO:0016491(oxidoreductase activity);GO:0016787(hydrolase activity);GO:0006730(one-carbon metabolic process);GO:0016874(ligase activity);GO:0005515(protein binding);GO:0008152(metabolic process);GO:0008652(cellular amino acid biosynthetic process);GO:0006164(purine nucleotide biosynthetic process);GO:0035999(tetrahydrofolate interconversion);GO:0070062(extracellular exosome);GO:0005739(mitochondrion);GO:0001843(neural tube closure);GO:0007507(heart development);GO:0046655(folic acid metabolic process);GO:0004477(methenyltetrahydrofolate cyclohydrolase activity);GO:0004486(methylenetetrahydrofolate dehydrogenase [NAD(P)+] activity);GO:0004487(methylenetetrahydrofolate dehydrogenase (NAD+) activity);GO:0000105(histidine biosynthetic process);GO:0006555(methionine metabolic process);GO:0009069(serine family amino acid metabolic process);GO:0009070(serine family amino acid biosynthetic process);GO:0009086(methionine biosynthetic process);GO:0009113(purine nucleobase biosynthetic process);GO:0009257(10-formyltetrahydrofolate biosynthetic process);GO:0048702(embryonic neurocranium morphogenesis);GO:0048703(embryonic viscerocranium morphogenesis);GO:0061053(somite development);GO:0001780(neutrophil homeostasis);GO:0019346(transsulfuration)","00670(One carbon pool by folate)","NA","NA","methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1 [Source:HGNC Symbol;Acc:HGNC:7432]",{"v":0.220086,"d":"0.22"},{"v":0.204065,"d":"0.20"},{"v":1.07850929850783,"d":"1.08"},{"v":0.109038614934438,"d":"0.11"},1,1,"up","no"]
[101731,0,"chr19","-",40844922,40850440,"ENST00000596719",6,1384,"MSTRG.8166","CYP2A6","GO:0016020(membrane);GO:0046872(metal ion binding);GO:0004497(monooxygenase activity);GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005506(iron ion binding);GO:0016705(oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen);GO:0020037(heme binding);GO:0016712(oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen);GO:0008392(arachidonic acid epoxygenase activity);GO:0008395(steroid hydroxylase activity);GO:0019373(epoxygenase P450 pathway);GO:0043231(intracellular membrane-bounded organelle);GO:0031090(organelle membrane);GO:0019899(enzyme binding);GO:0005881(cytoplasmic microtubule);GO:0008202(steroid metabolic process);GO:0017144(drug metabolic process);GO:0042738(exogenous drug catabolic process);GO:0009804(coumarin metabolic process);GO:0008389(coumarin 7-hydroxylase activity);GO:0046226(coumarin catabolic process);GO:0016021(integral component of membrane)","00830(Retinol metabolism);00232(Caffeine metabolism);00980(Metabolism of xenobiotics by cytochrome P450);00982(Drug metabolism - cytochrome P450);00983(Drug metabolism - other enzymes);05204(Chemical carcinogenesis)","NA","NA","cytochrome P450 family 2 subfamily A member 6 [Source:HGNC Symbol;Acc:HGNC:2610]",{"v":0.077261,"d":"0.08"},{"v":0.042297,"d":"0.04"},{"v":1.82663073031184,"d":"1.83"},{"v":0.869185009776208,"d":"0.87"},1,1,"up","no"]
[111291,0,"chr2","-",74464417,74465400,"ENST00000486036",2,811,"ENSG00000115275","MOGS","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005783(endoplasmic reticulum);GO:0016787(hydrolase activity);GO:0003824(catalytic activity);GO:0005789(endoplasmic reticulum membrane);GO:0008152(metabolic process);GO:0016798(hydrolase activity, acting on glycosyl bonds);GO:0070062(extracellular exosome);GO:0006457(protein folding);GO:0004573(mannosyl-oligosaccharide glucosidase activity);GO:0009311(oligosaccharide metabolic process);GO:0006487(protein N-linked glycosylation);GO:0015926(glucosidase activity)","00510(N-Glycan biosynthesis);04141(Protein processing in endoplasmic reticulum)","NA","NA","mannosyl-oligosaccharide glucosidase [Source:HGNC Symbol;Acc:HGNC:24862]",{"v":0.034597,"d":"0.03"},{"v":0.333372,"d":"0.33"},{"v":0.10377896164045,"d":"0.10"},{"v":-3.26841408869926,"d":"-3.27"},1,1,"down","no"]
[95303,0,"chr19","-",5705911,5708958,"ENST00000591321",4,913,"MSTRG.7713","LONP1","GO:0016020(membrane);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0005634(nucleus);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0016787(hydrolase activity);GO:0005739(mitochondrion);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0008233(peptidase activity);GO:0006508(proteolysis);GO:0004252(serine-type endopeptidase activity);GO:0005759(mitochondrial matrix);GO:0008236(serine-type peptidase activity);GO:0030163(protein catabolic process);GO:0001666(response to hypoxia);GO:0004176(ATP-dependent peptidase activity);GO:0043565(sequence-specific DNA binding);GO:0006515(misfolded or incompletely synthesized protein catabolic process);GO:0034599(cellular response to oxidative stress);GO:0070407(oxidation-dependent protein catabolic process);GO:0042645(mitochondrial nucleoid);GO:0070182(DNA polymerase binding);GO:0007005(mitochondrion organization);GO:0051260(protein homooligomerization);GO:0000002(mitochondrial genome maintenance);GO:0051603(proteolysis involved in cellular protein catabolic process);GO:0003727(single-stranded RNA binding);GO:0043531(ADP binding);GO:0003697(single-stranded DNA binding);GO:0016887(ATPase activity);GO:0051880(G-quadruplex DNA binding);GO:0070361(mitochondrial light strand promoter anti-sense binding);GO:0070362(mitochondrial heavy strand promoter anti-sense binding);GO:0007568(aging);GO:0009725(response to hormone);GO:0010044(response to aluminum ion);GO:0032042(mitochondrial DNA metabolic process);GO:0043623(cellular protein complex assembly);GO:0051131(chaperone-mediated protein complex assembly);GO:0090296(regulation of mitochondrial DNA replication)","NA","NA","NA","lon peptidase 1, mitochondrial [Source:HGNC Symbol;Acc:HGNC:9479]",0,{"v":0.118277,"d":"0.12"},"-inf","-inf",1,1,"down","no"]
[107552,0,"chr2","-",17716750,17746412,"ENST00000381272",12,1803,"MSTRG.8528","SMC6","GO:0005634(nucleus);GO:0016607(nuclear speck);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0005654(nucleoplasm);GO:0005694(chromosome);GO:0006281(DNA repair);GO:0005515(protein binding);GO:0006310(DNA recombination);GO:0006974(cellular response to DNA damage stimulus);GO:0000724(double-strand break repair via homologous recombination);GO:0030915(Smc5-Smc6 complex);GO:0000781(chromosome, telomeric region);GO:0031625(ubiquitin protein ligase binding);GO:0016605(PML body);GO:0090398(cellular senescence);GO:0005622(intracellular);GO:0035861(site of double-strand break);GO:0051984(positive regulation of chromosome segregation);GO:0000722(telomere maintenance via recombination);GO:0000803(sex chromosome);GO:0035061(interchromatin granule)","NA","NA","NA","structural maintenance of chromosomes 6 [Source:HGNC Symbol;Acc:HGNC:20466]",{"v":0.07631,"d":"0.08"},{"v":0.125021,"d":"0.13"},{"v":0.610377456587293,"d":"0.61"},{"v":-0.712226415595504,"d":"-0.71"},1,1,"down","no"]
[31530,0,"chr11","+",66011841,66013505,"ENST00000312134",3,759,"ENSG00000175315","CST6","GO:0005576(extracellular region);GO:0005615(extracellular space);GO:0004869(cysteine-type endopeptidase inhibitor activity);GO:0030414(peptidase inhibitor activity);GO:0010466(negative regulation of peptidase activity);GO:0070062(extracellular exosome);GO:0009653(anatomical structure morphogenesis);GO:0002020(protease binding);GO:2000117(negative regulation of cysteine-type endopeptidase activity);GO:0008544(epidermis development);GO:0001533(cornified envelope)","NA","NA","NA","cystatin E/M [Source:HGNC Symbol;Acc:HGNC:2478]",{"v":0.067652,"d":"0.07"},{"v":0.056062,"d":"0.06"},{"v":1.20673540009275,"d":"1.21"},{"v":0.271109372180321,"d":"0.27"},1,1,"up","no"]
[132409,0,"chr22","+",49918733,49926505,"ENST00000483652",9,1994,"MSTRG.10593","CRELD2","GO:0005509(calcium ion binding);GO:0005783(endoplasmic reticulum);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0005615(extracellular space);GO:0005794(Golgi apparatus)","NA","NA","NA","cysteine rich with EGF like domains 2 [Source:HGNC Symbol;Acc:HGNC:28150]",{"v":0.153028,"d":"0.15"},{"v":0.729995,"d":"0.73"},{"v":0.209628833074199,"d":"0.21"},{"v":-2.25409093110213,"d":"-2.25"},1,1,"down","no"]
[117009,0,"chr2","+",181458241,181479716,"ENST00000478440",3,1144,"MSTRG.9287","ITGA4","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0046872(metal ion binding);GO:0007155(cell adhesion);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0007229(integrin-mediated signaling pathway);GO:0008305(integrin complex);GO:0005925(focal adhesion);GO:0050776(regulation of immune response);GO:0050900(leukocyte migration);GO:0070062(extracellular exosome);GO:0009986(cell surface);GO:0030198(extracellular matrix organization);GO:0043113(receptor clustering);GO:0007160(cell-matrix adhesion);GO:0015026(coreceptor activity);GO:0050839(cell adhesion molecule binding);GO:0034446(substrate adhesion-dependent cell spreading);GO:0035987(endodermal cell differentiation);GO:0019960(C-X3-C chemokine binding);GO:0034113(heterotypic cell-cell adhesion);GO:0007159(leukocyte cell-cell adhesion);GO:0030183(B cell differentiation);GO:0050901(leukocyte tethering or rolling);GO:0003366(cell-matrix adhesion involved in ameboidal cell migration);GO:0090074(negative regulation of protein homodimerization activity);GO:0034669(integrin alpha4-beta7 complex);GO:0001968(fibronectin binding);GO:0003823(antigen binding);GO:1990405(protein antigen binding);GO:0002687(positive regulation of leukocyte migration);GO:0050904(diapedesis);GO:0071345(cellular response to cytokine stimulus);GO:0098657(import into cell);GO:1903039(positive regulation of leukocyte cell-cell adhesion);GO:1903238(positive regulation of leukocyte tethering or rolling);GO:1990771(clathrin-dependent extracellular exosome endocytosis);GO:2000406(positive regulation of T cell migration)","04151(PI3K-Akt signaling pathway);04512(ECM-receptor interaction);04514(Cell adhesion molecules (CAMs));04510(Focal adhesion);04810(Regulation of actin cytoskeleton);04640(Hematopoietic cell lineage);04670(Leukocyte transendothelial migration);04672(Intestinal immune network for IgA production);05410(Hypertrophic cardiomyopathy (HCM));05412(Arrhythmogenic right ventricular cardiomyopathy (ARVC));05414(Dilated cardiomyopathy (DCM));05165(Human papillomavirus infection);05140(Leishmaniasis)","NA","NA","integrin subunit alpha 4 [Source:HGNC Symbol;Acc:HGNC:6140]",{"v":0.413381,"d":"0.41"},{"v":0.547605,"d":"0.55"},{"v":0.754889016718255,"d":"0.75"},{"v":-0.405663538925965,"d":"-0.41"},1,1,"down","no"]
[134426,0,"chr3","-",32529630,32537272,"ENST00000472985",6,646,"MSTRG.10781","DYNC1LI1","GO:0003723(RNA binding);GO:0006810(transport);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0051301(cell division);GO:0005694(chromosome);GO:0003777(microtubule motor activity);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0007049(cell cycle);GO:0005874(microtubule);GO:0003774(motor activity);GO:0007018(microtubule-based movement);GO:0005868(cytoplasmic dynein complex);GO:0000922(spindle pole);GO:0005813(centrosome);GO:0005886(plasma membrane);GO:0000775(chromosome, centromeric region);GO:0000776(kinetochore);GO:0000777(condensed chromosome kinetochore);GO:0030286(dynein complex);GO:0005829(cytosol);GO:0016032(viral process);GO:0043312(neutrophil degranulation);GO:0007062(sister chromatid cohesion);GO:0019886(antigen processing and presentation of exogenous peptide antigen via MHC class II);GO:0030667(secretory granule membrane);GO:0006888(ER to Golgi vesicle-mediated transport);GO:0090267(positive regulation of mitotic cell cycle spindle assembly checkpoint);GO:0101003(ficolin-1-rich granule membrane);GO:0000226(microtubule cytoskeleton organization);GO:0019003(GDP binding);GO:0045504(dynein heavy chain binding)","04145(Phagosome);04962(Vasopressin-regulated water reabsorption);05132(Salmonella infection)","NA","NA","dynein cytoplasmic 1 light intermediate chain 1 [Source:HGNC Symbol;Acc:HGNC:18745]",0,{"v":0.02458,"d":"0.02"},"-inf","-inf",1,1,"down","no"]
[97402,0,"chr19","+",13759076,13762931,"ENST00000587019",4,756,"MSTRG.7879","CCDC130","GO:0005515(protein binding);GO:0005575(cellular_component);GO:0009615(response to virus)","NA","NA","NA","coiled-coil domain containing 130 [Source:HGNC Symbol;Acc:HGNC:28118]",{"v":1.354413,"d":"1.35"},{"v":0.267895,"d":"0.27"},{"v":5.05576065249445,"d":"5.06"},{"v":2.33792816572371,"d":"2.34"},1,1,"up","no"]
[122107,0,"chr20","-",14322988,14337608,"ENST00000378053",2,4776,"ENSG00000125848","FLRT3","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0007155(cell adhesion);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0042803(protein homodimerization activity);GO:0005886(plasma membrane);GO:0042995(cell projection);GO:0005576(extracellular region);GO:0007275(multicellular organism development);GO:0005578(proteinaceous extracellular matrix);GO:0030054(cell junction);GO:0005925(focal adhesion);GO:0005737(cytoplasm);GO:0005887(integral component of plasma membrane);GO:0005515(protein binding);GO:0030424(axon);GO:0044295(axonal growth cone);GO:0007507(heart development);GO:0004860(protein kinase inhibitor activity);GO:0006469(negative regulation of protein kinase activity);GO:0019221(cytokine-mediated signaling pathway);GO:0046426(negative regulation of JAK-STAT cascade);GO:0030674(protein binding, bridging);GO:0031175(neuron projection development);GO:0008543(fibroblast growth factor receptor signaling pathway);GO:0005057(signal transducer activity, downstream of receptor);GO:0050919(negative chemotaxis);GO:0007416(synapse assembly);GO:0097060(synaptic membrane);GO:0048678(response to axon injury);GO:0098742(cell-cell adhesion via plasma-membrane adhesion molecules);GO:0043679(axon terminus);GO:0048598(embryonic morphogenesis);GO:1990138(neuron projection extension);GO:0060322(head development);GO:0005104(fibroblast growth factor receptor binding);GO:0045499(chemorepellent activity);GO:0003345(proepicardium cell migration involved in pericardium morphogenesis);GO:0007411(axon guidance);GO:0051965(positive regulation of synapse assembly);GO:0005615(extracellular space);GO:0005911(cell-cell junction)","NA","NA","NA","fibronectin leucine rich transmembrane protein 3 [Source:HGNC Symbol;Acc:HGNC:3762]",0,{"v":0.009553,"d":"0.01"},"-inf","-inf",1,1,"down","no"]
[59075,0,"chr14","-",103521648,103522833,"ENST00000554705",3,803,"ENSG00000166165","CKB","GO:0005737(cytoplasm);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0005829(cytosol);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0003824(catalytic activity);GO:0016772(transferase activity, transferring phosphorus-containing groups);GO:0005515(protein binding);GO:0070062(extracellular exosome);GO:0005615(extracellular space);GO:0021762(substantia nigra development);GO:0031625(ubiquitin protein ligase binding);GO:0004111(creatine kinase activity);GO:0006600(creatine metabolic process);GO:0007420(brain development);GO:0021549(cerebellum development);GO:0030644(cellular chloride ion homeostasis);GO:0005634(nucleus);GO:0005739(mitochondrion);GO:0030425(dendrite);GO:0043025(neuronal cell body);GO:0043209(myelin sheath)","00330(Arginine and proline metabolism)","NA","NA","creatine kinase B [Source:HGNC Symbol;Acc:HGNC:1991]",0,0,1,0,1,1,"no","no"]
[183483,0,"chr8","-",42472249,42502628,"ENST00000522707",2,751,"ENSG00000168575","SLC20A2","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0015293(symporter activity);GO:0055085(transmembrane transport);GO:0006811(ion transport);GO:0005886(plasma membrane);GO:0006814(sodium ion transport);GO:0035725(sodium ion transmembrane transport);GO:0046718(viral entry into host cell);GO:0070062(extracellular exosome);GO:0005315(inorganic phosphate transmembrane transporter activity);GO:0006817(phosphate ion transport);GO:0035435(phosphate ion transmembrane transport);GO:0016032(viral process);GO:0005887(integral component of plasma membrane);GO:0004872(receptor activity);GO:0005436(sodium:phosphate symporter activity);GO:0001618(virus receptor activity);GO:0015321(sodium-dependent phosphate transmembrane transporter activity);GO:0015319(sodium:inorganic phosphate symporter activity);GO:0044341(sodium-dependent phosphate transport)","NA","NA","NA","solute carrier family 20 member 2 [Source:HGNC Symbol;Acc:HGNC:10947]",0,{"v":8.7e-05,"d":"0.00"},"-inf","-inf",1,1,"down","no"]
[37828,0,"chr12","+",6452042,6453673,"ENST00000544826",3,567,"MSTRG.3050","TAPBPL","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005794(Golgi apparatus);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0000139(Golgi membrane);GO:0002376(immune system process);GO:0043231(intracellular membrane-bounded organelle);GO:0031090(organelle membrane);GO:0032403(protein complex binding);GO:0002590(negative regulation of antigen processing and presentation of peptide antigen via MHC class I)","NA","NA","NA","TAP binding protein like [Source:HGNC Symbol;Acc:HGNC:30683]",{"v":0.380418,"d":"0.38"},{"v":0.14111,"d":"0.14"},{"v":2.69589681808518,"d":"2.70"},{"v":1.43076528031595,"d":"1.43"},1,1,"up","no"]
[42743,0,"chr12","+",55930972,55954015,"ENST00000331886",24,2909,"MSTRG.3452","DGKA","GO:0016020(membrane);GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0035556(intracellular signal transduction);GO:0005509(calcium ion binding);GO:0008152(metabolic process);GO:0003951(NAD+ kinase activity);GO:0004143(diacylglycerol kinase activity);GO:0007205(protein kinase C-activating G-protein coupled receptor signaling pathway);GO:0005543(phospholipid binding);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0030168(platelet activation);GO:0006654(phosphatidic acid biosynthetic process);GO:0046339(diacylglycerol metabolic process);GO:0046834(lipid phosphorylation);GO:0046486(glycerolipid metabolic process);GO:0005622(intracellular)","00561(Glycerolipid metabolism);00564(Glycerophospholipid metabolism);04070(Phosphatidylinositol signaling system);04072(Phospholipase D signaling pathway);05231(Choline metabolism in cancer)","K00901","EC:2.7.1.107","diacylglycerol kinase alpha [Source:HGNC Symbol;Acc:HGNC:2849]",{"v":12.533564,"d":"12.53"},{"v":0.224694,"d":"0.22"},{"v":55.780590491958,"d":"55.78"},{"v":5.80169130166862,"d":"5.80"},1,1,"up","no"]
[125270,0,"chr20","+",62550453,62570764,"ENST00000624914",4,1220,"ENSG00000174407","MIR1-1HG","NA","NA","NA","NA","MIR1-1 host gene [Source:HGNC Symbol;Acc:HGNC:16159]",{"v":0.055668,"d":"0.06"},{"v":6.731E-3,"d":"0.01"},{"v":8.2703907294607,"d":"8.27"},{"v":3.04795549023563,"d":"3.05"},1,1,"up","no"]
[42911,0,"chr12","-",56118968,56119939,"ENST00000550840",2,470,"MSTRG.3449","AC034102.7","NA","NA","NA","NA","NA",{"v":0.009562,"d":"0.01"},0,"inf","inf",1,1,"up","no"]
[148636,0,"chr4","-",81427065,81471915,"ENST00000264400",14,2277,"ENSG00000138670","RASGEF1B","GO:0007264(small GTPase mediated signal transduction);GO:0043547(positive regulation of GTPase activity);GO:0005085(guanyl-nucleotide exchange factor activity);GO:0030496(midbody);GO:0005768(endosome);GO:0005769(early endosome);GO:0005770(late endosome);GO:0005088(Ras guanyl-nucleotide exchange factor activity);GO:0005622(intracellular)","NA","NA","NA","RasGEF domain family member 1B [Source:HGNC Symbol;Acc:HGNC:24881]",0,{"v":0.119366,"d":"0.12"},"-inf","-inf",1,1,"down","no"]
[80844,0,"chr17","-",20863395,20896140,"ENST00000327925",4,2806,"MSTRG.6520","CCDC144NL","NA","NA","NA","NA","coiled-coil domain containing 144 family, N-terminal like [Source:HGNC Symbol;Acc:HGNC:33735]",{"v":0.015336,"d":"0.02"},0,"inf","inf",1,1,"up","no"]
[175321,0,"chr7","+",76433956,76442071,"ENST00000466960",4,659,"ENSG00000188372","ZP3","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0030246(carbohydrate binding);GO:0005794(Golgi apparatus);GO:0005783(endoplasmic reticulum);GO:0005886(plasma membrane);GO:0005576(extracellular region);GO:0005578(proteinaceous extracellular matrix);GO:0048471(perinuclear region of cytoplasm);GO:0005615(extracellular space);GO:0071421(manganese ion transmembrane transport);GO:0048015(phosphatidylinositol-mediated signaling);GO:0045893(positive regulation of transcription, DNA-templated);GO:0042802(identical protein binding);GO:0005515(protein binding);GO:0031012(extracellular matrix);GO:0042102(positive regulation of T cell proliferation);GO:0007338(single fertilization);GO:2000344(positive regulation of acrosome reaction);GO:0002081(outer acrosomal membrane);GO:0032753(positive regulation of interleukin-4 production);GO:0045892(negative regulation of transcription, DNA-templated);GO:0050729(positive regulation of inflammatory response);GO:0030141(secretory granule);GO:0007339(binding of sperm to zona pellucida);GO:0005771(multivesicular body);GO:0032729(positive regulation of interferon-gamma production);GO:0002455(humoral immune response mediated by circulating immunoglobulin);GO:0032190(acrosin binding);GO:0033157(regulation of intracellular protein transport);GO:0005384(manganese ion transmembrane transporter activity);GO:0001809(positive regulation of type IV hypersensitivity);GO:0001825(blastocyst formation);GO:0002687(positive regulation of leukocyte migration);GO:0002922(positive regulation of humoral immune response);GO:0006828(manganese ion transport);GO:0010513(positive regulation of phosphatidylinositol biosynthetic process);GO:0035636(multi-organism signaling);GO:0035803(egg coat formation);GO:0048599(oocyte development);GO:2000360(negative regulation of binding of sperm to zona pellucida);GO:2000368(positive regulation of acrosomal vesicle exocytosis);GO:2000386(positive regulation of ovarian follicle development);GO:2000388(positive regulation of antral ovarian follicle growth)","NA","NA","NA","zona pellucida glycoprotein 3 [Source:HGNC Symbol;Acc:HGNC:13189]",0,{"v":0.028197,"d":"0.03"},"-inf","-inf",1,1,"down","no"]
[36911,0,"chr11","+",129815871,129852961,"ENST00000529381",2,515,"ENSG00000151715","TMEM45B","GO:0016020(membrane);GO:0016021(integral component of membrane)","NA","NA","NA","transmembrane protein 45B [Source:HGNC Symbol;Acc:HGNC:25194]",0,{"v":0.365419,"d":"0.37"},"-inf","-inf",1,1,"down","no"]
[101241,0,"chr19","-",39386482,39391117,"ENST00000416728",13,1383,"MSTRG.8132","PAF1","GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0030054(cell junction);GO:0003682(chromatin binding);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0001711(endodermal cell fate commitment);GO:0006368(transcription elongation from RNA polymerase II promoter);GO:0016570(histone modification);GO:0019827(stem cell population maintenance);GO:0071222(cellular response to lipopolysaccharide);GO:0016593(Cdc73/Paf1 complex);GO:0005515(protein binding);GO:0016055(Wnt signaling pathway);GO:0016567(protein ubiquitination);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0006366(transcription from RNA polymerase II promoter);GO:0045638(negative regulation of myeloid cell differentiation);GO:0005737(cytoplasm);GO:0006378(mRNA polyadenylation);GO:0032968(positive regulation of transcription elongation from RNA polymerase II promoter);GO:0010390(histone monoubiquitination);GO:0033523(histone H2B ubiquitination);GO:0000993(RNA polymerase II core binding);GO:0031442(positive regulation of mRNA 3'-end processing);GO:1902808(positive regulation of cell cycle G1/S phase transition);GO:0016584(nucleosome positioning);GO:0031062(positive regulation of histone methylation);GO:0034504(protein localization to nucleus);GO:0016020(membrane)","NA","NA","NA","PAF1 homolog, Paf1/RNA polymerase II complex component [Source:HGNC Symbol;Acc:HGNC:25459]",{"v":0.130022,"d":"0.13"},{"v":0.009504,"d":"0.01"},{"v":13.680765993266,"d":"13.68"},{"v":3.77407710462493,"d":"3.77"},1,1,"up","no"]
[8382,0,"chr1","+",99970006,100024014,"ENST00000638336",6,2438,"MSTRG.739","SLC35A3","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0000139(Golgi membrane);GO:0005351(sugar:proton symporter activity);GO:0008643(carbohydrate transport);GO:0015992(proton transport);GO:0006810(transport);GO:0005794(Golgi apparatus);GO:0005515(protein binding);GO:0005462(UDP-N-acetylglucosamine transmembrane transporter activity);GO:0015788(UDP-N-acetylglucosamine transport);GO:1990569(UDP-N-acetylglucosamine transmembrane transport);GO:0006047(UDP-N-acetylglucosamine metabolic process)","NA","NA","NA","solute carrier family 35 member A3 [Source:HGNC Symbol;Acc:HGNC:11023]",{"v":0.017181,"d":"0.02"},0,"inf","inf",1,1,"up","no"]
[112811,0,"chr2","+",99181152,99195178,"ENST00000473743",6,567,"MSTRG.8997","MRPL30","GO:0030529(intracellular ribonucleoprotein complex);GO:0003735(structural constituent of ribosome);GO:0006412(translation);GO:0005840(ribosome);GO:0005739(mitochondrion);GO:0015934(large ribosomal subunit);GO:0005743(mitochondrial inner membrane);GO:0070125(mitochondrial translational elongation);GO:0070126(mitochondrial translational termination);GO:0005762(mitochondrial large ribosomal subunit)","03010(Ribosome)","NA","NA","mitochondrial ribosomal protein L30 [Source:HGNC Symbol;Acc:HGNC:14036]",0,{"v":0.681839,"d":"0.68"},"-inf","-inf",1,1,"down","no"]
[155276,0,"chr5","+",65582556,65587278,"ENST00000513773",4,955,"MSTRG.12086","PPWD1","GO:0006397(mRNA processing);GO:0008380(RNA splicing);GO:0005634(nucleus);GO:0016853(isomerase activity);GO:0003755(peptidyl-prolyl cis-trans isomerase activity);GO:0000413(protein peptidyl-prolyl isomerization);GO:0006457(protein folding);GO:0005681(spliceosomal complex);GO:0016604(nuclear body);GO:0005654(nucleoplasm);GO:0000398(mRNA splicing, via spliceosome);GO:0071013(catalytic step 2 spliceosome)","NA","NA","NA","peptidylprolyl isomerase domain and WD repeat containing 1 [Source:HGNC Symbol;Acc:HGNC:28954]",{"v":0.311136,"d":"0.31"},{"v":1.72531,"d":"1.73"},{"v":0.180336287391831,"d":"0.18"},{"v":-2.47123836881721,"d":"-2.47"},1,1,"down","no"]
[162586,0,"chr6","-",4998688,5004047,"ENST00000468105",5,632,"ENSG00000124787","RPP40","GO:0005634(nucleus);GO:0008033(tRNA processing);GO:0016787(hydrolase activity);GO:0090501(RNA phosphodiester bond hydrolysis);GO:0090502(RNA phosphodiester bond hydrolysis, endonucleolytic);GO:0005730(nucleolus);GO:0005654(nucleoplasm);GO:0006364(rRNA processing);GO:0004526(ribonuclease P activity);GO:0001682(tRNA 5'-leader removal);GO:0005655(nucleolar ribonuclease P complex)","03013(RNA transport);03008(Ribosome biogenesis in eukaryotes)","NA","NA","ribonuclease P/MRP subunit p40 [Source:HGNC Symbol;Acc:HGNC:20992]",0,{"v":0.015936,"d":"0.02"},"-inf","-inf",1,1,"down","no"]
[194689,0,"chr9","+",135702213,135793103,"ENST00000460750",32,4738,"ENSG00000107147","KCNT1","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005267(potassium channel activity);GO:0006811(ion transport);GO:0006813(potassium ion transport);GO:0071805(potassium ion transmembrane transport);GO:0005886(plasma membrane);GO:0005249(voltage-gated potassium channel activity);GO:0008076(voltage-gated potassium channel complex);GO:0015269(calcium-activated potassium channel activity)","NA","NA","NA","potassium sodium-activated channel subfamily T member 1 [Source:HGNC Symbol;Acc:HGNC:18865]",0,{"v":0.012011,"d":"0.01"},"-inf","-inf",1,1,"down","no"]
[103324,0,"chr19","+",47729617,47741865,"ENST00000540884",3,1215,"ENSG00000024422","EHD2","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005525(GTP binding);GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0016787(hydrolase activity);GO:0005509(calcium ion binding);GO:0005886(plasma membrane);GO:0005829(cytosol);GO:0045171(intercellular bridge);GO:0019904(protein domain specific binding);GO:0006897(endocytosis);GO:0030036(actin cytoskeleton organization);GO:0030866(cortical actin cytoskeleton organization);GO:0032456(endocytic recycling);GO:0072659(protein localization to plasma membrane);GO:0097320(plasma membrane tubulation);GO:1901741(positive regulation of myoblast fusion);GO:2001137(positive regulation of endocytic recycling);GO:0005901(caveola);GO:0015630(microtubule cytoskeleton);GO:0019898(extrinsic component of membrane);GO:0048471(perinuclear region of cytoplasm);GO:0005515(protein binding);GO:0005768(endosome);GO:0070062(extracellular exosome);GO:0010008(endosome membrane);GO:0055038(recycling endosome membrane);GO:0005634(nucleus);GO:0007596(blood coagulation);GO:0003676(nucleic acid binding)","04144(Endocytosis)","NA","NA","EH domain containing 2 [Source:HGNC Symbol;Acc:HGNC:3243]",0,{"v":0.034685,"d":"0.03"},"-inf","-inf",1,1,"down","no"]
[180453,0,"chr7","+",154928517,154945398,"ENST00000397551",3,1692,"ENSG00000214106","PAXIP1-AS2","NA","NA","NA","NA","PAXIP1 antisense RNA 2 [Source:HGNC Symbol;Acc:HGNC:48958]",{"v":0.035417,"d":"0.04"},{"v":0.164604,"d":"0.16"},{"v":0.215164880561833,"d":"0.22"},{"v":-2.21648547597976,"d":"-2.22"},1,1,"down","no"]
[90625,"j","chr18","-",9557142,9614578,"MSTRG.7416.12",16,2374,"MSTRG.7416","PPP4R1","NA","NA","NA","NA","NA",0,{"v":3.77874,"d":"3.78"},"-inf","-inf",1,1,"down","no"]
[64950,0,"chr15","-",75364046,75368609,"ENST00000569355",7,867,"MSTRG.5311","MAN2C1","GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0005654(nucleoplasm);GO:0030246(carbohydrate binding);GO:0016787(hydrolase activity);GO:0003824(catalytic activity);GO:0005975(carbohydrate metabolic process);GO:0008152(metabolic process);GO:0016798(hydrolase activity, acting on glycosyl bonds);GO:0004559(alpha-mannosidase activity);GO:0006013(mannose metabolic process);GO:0005829(cytosol);GO:0006517(protein deglycosylation);GO:0009313(oligosaccharide catabolic process);GO:0005773(vacuole)","00511(Other glycan degradation)","NA","NA","mannosidase alpha class 2C member 1 [Source:HGNC Symbol;Acc:HGNC:6827]",{"v":0.000152,"d":"0.00"},{"v":0.085675,"d":"0.09"},{"v":0.00177414648380508,"d":"0.00"},{"v":-9.13865915285031,"d":"-9.14"},1,1,"down","no"]
[96870,0,"chr19","+",11639776,11686569,"ENST00000344893",10,3383,"MSTRG.7830","AC008543.1","NA","NA","NA","NA","NA",0,{"v":0.013486,"d":"0.01"},"-inf","-inf",1,1,"down","no"]
[89425,0,"chr17","+",81695956,81698356,"ENST00000571647",1,2401,"MSTRG.7328","HGS","GO:0005622(intracellular);GO:0006886(intracellular protein transport);GO:0006810(transport);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0015031(protein transport);GO:0043231(intracellular membrane-bounded organelle);GO:0046872(metal ion binding);GO:0005829(cytosol);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0005515(protein binding);GO:0005764(lysosome);GO:0005768(endosome);GO:0070062(extracellular exosome);GO:0010628(positive regulation of gene expression);GO:0072657(protein localization to membrane);GO:0061024(membrane organization);GO:0016197(endosomal transport);GO:0016236(macroautophagy);GO:0036258(multivesicular body assembly);GO:0016579(protein deubiquitination);GO:0031901(early endosome membrane);GO:0007165(signal transduction);GO:0019904(protein domain specific binding);GO:0032585(multivesicular body membrane);GO:1903543(positive regulation of exosomal secretion);GO:0008285(negative regulation of cell proliferation);GO:0006622(protein targeting to lysosome);GO:0010324(membrane invagination);GO:0042059(negative regulation of epidermal growth factor receptor signaling pathway);GO:0042176(regulation of protein catabolic process);GO:0043405(regulation of MAP kinase activity);GO:0046426(negative regulation of JAK-STAT cascade);GO:0005769(early endosome);GO:0033565(ESCRT-0 complex)","04144(Endocytosis);04145(Phagosome)","NA","NA","hepatocyte growth factor-regulated tyrosine kinase substrate [Source:HGNC Symbol;Acc:HGNC:4897]",{"v":0.358747,"d":"0.36"},{"v":0.001009,"d":"0.00"},{"v":355.547076313181,"d":"355.55"},{"v":8.47389678271956,"d":"8.47"},1,1,"up","no"]
[10179,0,"chr1","-",147184305,147225353,"ENST00000441068",9,1696,"MSTRG.872","FMO5","GO:0004497(monooxygenase activity);GO:0004499(N,N-dimethylaniline monooxygenase activity);GO:0016491(oxidoreductase activity);GO:0050660(flavin adenine dinucleotide binding);GO:0050661(NADP binding);GO:0055114(oxidation-reduction process);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005783(endoplasmic reticulum);GO:0005829(cytosol);GO:0005789(endoplasmic reticulum membrane);GO:0008150(biological_process);GO:0043231(intracellular membrane-bounded organelle);GO:0031090(organelle membrane)","00982(Drug metabolism - cytochrome P450)","K00485","EC:1.14.13.8","flavin containing monooxygenase 5 [Source:HGNC Symbol;Acc:HGNC:3773]",{"v":0.039995,"d":"0.04"},0,"inf","inf",1,1,"up","no"]
[29872,0,"chr11","-",61302581,61311349,"ENST00000539332",6,1767,"MSTRG.2440","DDB1","GO:0005634(nucleus);GO:0003676(nucleic acid binding);GO:0005737(cytoplasm);GO:0005654(nucleoplasm);GO:0016567(protein ubiquitination);GO:0003677(DNA binding);GO:0006281(DNA repair);GO:0005515(protein binding);GO:0006974(cellular response to DNA damage stimulus);GO:0005615(extracellular space);GO:0070062(extracellular exosome);GO:0043687(post-translational protein modification);GO:0000784(nuclear chromosome, telomeric region);GO:0016032(viral process);GO:0042787(protein ubiquitination involved in ubiquitin-dependent protein catabolic process);GO:0030674(protein binding, bridging);GO:0043161(proteasome-mediated ubiquitin-dependent protein catabolic process);GO:0032403(protein complex binding);GO:0045070(positive regulation of viral genome replication);GO:0010498(proteasomal protein catabolic process);GO:1901990(regulation of mitotic cell cycle phase transition);GO:0003684(damaged DNA binding);GO:0006283(transcription-coupled nucleotide-excision repair);GO:0097602(cullin family protein binding);GO:0042769(DNA damage response, detection of DNA damage);GO:0035518(histone H2A monoubiquitination);GO:0046726(positive regulation by virus of viral protein levels in host cell);GO:0006293(nucleotide-excision repair, preincision complex stabilization);GO:0006295(nucleotide-excision repair, DNA incision, 3'-to lesion);GO:0006296(nucleotide-excision repair, DNA incision, 5'-to lesion);GO:0033683(nucleotide-excision repair, DNA incision);GO:0070911(global genome nucleotide-excision repair);GO:0000715(nucleotide-excision repair, DNA damage recognition);GO:0000717(nucleotide-excision repair, DNA duplex unwinding);GO:0006294(nucleotide-excision repair, preincision complex assembly);GO:0006289(nucleotide-excision repair);GO:0080008(Cul4-RING E3 ubiquitin ligase complex);GO:0031464(Cul4A-RING E3 ubiquitin ligase complex);GO:0031465(Cul4B-RING E3 ubiquitin ligase complex);GO:0070914(UV-damage excision repair);GO:0016055(Wnt signaling pathway);GO:0043066(negative regulation of apoptotic process);GO:0051702(interaction with symbiont);GO:1902188(positive regulation of viral release from host cell)","04120(Ubiquitin mediated proteolysis);03420(Nucleotide excision repair);05203(Viral carcinogenesis);05161(Hepatitis B)","NA","NA","damage specific DNA binding protein 1 [Source:HGNC Symbol;Acc:HGNC:2717]",{"v":0.209876,"d":"0.21"},{"v":0.141776,"d":"0.14"},{"v":1.48033517661663,"d":"1.48"},{"v":0.565923866999557,"d":"0.57"},1,1,"up","no"]
[115624,0,"chr2","-",159412432,159432950,"ENST00000441143",5,580,"MSTRG.9182","BAZ2B","GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0005515(protein binding)","NA","NA","NA","bromodomain adjacent to zinc finger domain 2B [Source:HGNC Symbol;Acc:HGNC:963]",0,{"v":0.29044,"d":"0.29"},"-inf","-inf",1,1,"down","no"]
[155569,0,"chr5","+",70049657,70077596,"ENST00000506734",9,1550,"ENSG00000205571","SMN2","GO:0005634(nucleus);GO:0003723(RNA binding);GO:0006397(mRNA processing);GO:0008380(RNA splicing);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0042995(cell projection);GO:0005515(protein binding);GO:0007399(nervous system development);GO:0005654(nucleoplasm);GO:0042802(identical protein binding);GO:0000387(spliceosomal snRNP assembly);GO:0043204(perikaryon);GO:0043005(neuron projection);GO:0030018(Z disc);GO:0006353(DNA-templated transcription, termination);GO:0051170(nuclear import);GO:0032797(SMN complex);GO:0034719(SMN-Sm protein complex);GO:0097504(Gemini of coiled bodies);GO:0015030(Cajal body);GO:0000245(spliceosomal complex assembly);GO:0036464(cytoplasmic ribonucleoprotein granule)","03013(RNA transport)","NA","NA","survival of motor neuron 2, centromeric [Source:HGNC Symbol;Acc:HGNC:11118]",0,0,1,0,1,1,"no","no"]
[61707,0,"chr15","-",43205992,43207239,"ENST00000565459",2,679,"MSTRG.5018","EPB42","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005886(plasma membrane);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0007010(cytoskeleton organization);GO:0003810(protein-glutamine gamma-glutamyltransferase activity);GO:0018149(peptide cross-linking);GO:0008360(regulation of cell shape);GO:0043249(erythrocyte maturation);GO:0005200(structural constituent of cytoskeleton);GO:0005524(ATP binding);GO:0000902(cell morphogenesis);GO:0020027(hemoglobin metabolic process);GO:0048536(spleen development);GO:0050801(ion homeostasis);GO:0055072(iron ion homeostasis);GO:0030863(cortical cytoskeleton)","NA","NA","NA","erythrocyte membrane protein band 4.2 [Source:HGNC Symbol;Acc:HGNC:3381]",{"v":0.068942,"d":"0.07"},{"v":0.288966,"d":"0.29"},{"v":0.238581701653482,"d":"0.24"},{"v":-2.06744469706002,"d":"-2.07"},1,1,"down","no"]
[127292,0,"chr21","-",39597147,39599656,"ENST00000489821",2,1159,"ENSG00000184809","B3GALT5-AS1","NA","NA","NA","NA","B3GALT5 antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:16424]",0,{"v":0.026243,"d":"0.03"},"-inf","-inf",1,1,"down","no"]
[128114,0,"chr21","+",46644343,46652952,"ENST00000455177",4,581,"MSTRG.10096","PRMT2","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0008168(methyltransferase activity);GO:0016740(transferase activity);GO:0032259(methylation);GO:0042803(protein homodimerization activity);GO:0005515(protein binding);GO:0006479(protein methylation);GO:0003713(transcription coactivator activity);GO:0045893(positive regulation of transcription, DNA-templated);GO:0005730(nucleolus);GO:0030331(estrogen receptor binding);GO:0042974(retinoic acid receptor binding);GO:0032088(negative regulation of NF-kappaB transcription factor activity);GO:0043065(positive regulation of apoptotic process);GO:0004871(signal transducer activity);GO:0007165(signal transduction);GO:0045892(negative regulation of transcription, DNA-templated);GO:0016274(protein-arginine N-methyltransferase activity);GO:0050681(androgen receptor binding);GO:0042054(histone methyltransferase activity);GO:0008469(histone-arginine N-methyltransferase activity);GO:0035242(protein-arginine omega-N asymmetric methyltransferase activity);GO:0019919(peptidyl-arginine methylation, to asymmetrical-dimethyl arginine);GO:0034969(histone arginine methylation);GO:0035246(peptidyl-arginine N-methylation);GO:0046966(thyroid hormone receptor binding);GO:2000134(negative regulation of G1/S transition of mitotic cell cycle);GO:0048588(developmental cell growth);GO:0042975(peroxisome proliferator activated receptor binding);GO:0060765(regulation of androgen receptor signaling pathway);GO:0035189(Rb-E2F complex);GO:0033142(progesterone receptor binding);GO:0016571(histone methylation)","NA","NA","NA","protein arginine methyltransferase 2 [Source:HGNC Symbol;Acc:HGNC:5186]",{"v":0.8804,"d":"0.88"},{"v":1.155591,"d":"1.16"},{"v":0.761861246755989,"d":"0.76"},{"v":-0.392399822686618,"d":"-0.39"},1,1,"down","no"]
[142336,0,"chr3","+",161426427,161448242,"ENST00000473595",4,2845,"MSTRG.11317","LINC02067","NA","NA","NA","NA","long intergenic non-protein coding RNA 2067 [Source:HGNC Symbol;Acc:HGNC:52913]",{"v":0.008162,"d":"0.01"},{"v":0.051478,"d":"0.05"},{"v":0.158553168343759,"d":"0.16"},{"v":-2.6569613880028,"d":"-2.66"},1,1,"down","no"]
[89807,0,"chr17","-",82246318,82249835,"ENST00000580565",4,566,"MSTRG.7356","CSNK1D","GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0001934(positive regulation of protein phosphorylation);GO:0090263(positive regulation of canonical Wnt signaling pathway);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0005794(Golgi apparatus);GO:0005886(plasma membrane);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0048511(rhythmic process);GO:0016055(Wnt signaling pathway);GO:0048471(perinuclear region of cytoplasm);GO:0005813(centrosome);GO:0005815(microtubule organizing center);GO:0005819(spindle);GO:0000139(Golgi membrane);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0045296(cadherin binding);GO:0008360(regulation of cell shape);GO:0000086(G2/M transition of mitotic cell cycle);GO:0010389(regulation of G2/M transition of mitotic cell cycle);GO:0097711(ciliary basal body docking);GO:0005876(spindle microtubule);GO:0032922(circadian regulation of gene expression);GO:0006364(rRNA processing);GO:0048208(COPII vesicle coating);GO:0033116(endoplasmic reticulum-Golgi intermediate compartment membrane);GO:0042752(regulation of circadian rhythm);GO:0051225(spindle assembly);GO:0006897(endocytosis);GO:0032436(positive regulation of proteasomal ubiquitin-dependent protein catabolic process);GO:0018105(peptidyl-serine phosphorylation);GO:0050321(tau-protein kinase activity);GO:0042277(peptide binding);GO:0007020(microtubule nucleation);GO:0007030(Golgi organization);GO:0030177(positive regulation of Wnt signaling pathway);GO:0034067(protein localization to Golgi apparatus);GO:0061512(protein localization to cilium);GO:0071539(protein localization to centrosome);GO:1905426(positive regulation of Wnt-mediated midbrain dopaminergic neuron differentiation);GO:1905515(non-motile cilium assembly);GO:1990090(cellular response to nerve growth factor stimulus);GO:2000052(positive regulation of non-canonical Wnt signaling pathway);GO:0043005(neuron projection)","04340(Hedgehog signaling pathway);04390(Hippo signaling pathway);04540(Gap junction);04710(Circadian rhythm)","NA","NA","casein kinase 1 delta [Source:HGNC Symbol;Acc:HGNC:2452]",0,{"v":1.203246,"d":"1.20"},"-inf","-inf",1,1,"down","no"]
[72777,0,"chr16","-",48364850,48365724,"ENST00000573005",2,705,"ENSG00000196470","SIAH1","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0016740(transferase activity);GO:0016567(protein ubiquitination);GO:0007275(multicellular organism development);GO:0005515(protein binding);GO:0007049(cell cycle);GO:0006511(ubiquitin-dependent protein catabolic process);GO:0006915(apoptotic process);GO:0030154(cell differentiation);GO:0007283(spermatogenesis);GO:0042802(identical protein binding);GO:0005829(cytosol);GO:0044267(cellular protein metabolic process);GO:0000209(protein polyubiquitination);GO:0043065(positive regulation of apoptotic process);GO:0042787(protein ubiquitination involved in ubiquitin-dependent protein catabolic process);GO:0008022(protein C-terminus binding);GO:0007399(nervous system development);GO:0004842(ubiquitin-protein transferase activity);GO:0043161(proteasome-mediated ubiquitin-dependent protein catabolic process);GO:0007411(axon guidance);GO:0009653(anatomical structure morphogenesis);GO:2001244(positive regulation of intrinsic apoptotic signaling pathway);GO:0051402(neuron apoptotic process);GO:0030163(protein catabolic process);GO:0030877(beta-catenin destruction complex);GO:0061630(ubiquitin protein ligase activity);GO:0031648(protein destabilization);GO:0005769(early endosome);GO:0005886(plasma membrane)","04120(Ubiquitin mediated proteolysis);04310(Wnt signaling pathway);04115(p53 signaling pathway)","NA","NA","siah E3 ubiquitin protein ligase 1 [Source:HGNC Symbol;Acc:HGNC:10857]",{"v":0.042774,"d":"0.04"},{"v":0.05163,"d":"0.05"},{"v":0.828471818710052,"d":"0.83"},{"v":-0.271475471307551,"d":"-0.27"},1,1,"down","no"]
[199219,0,"chrX","-",107123427,107206433,"ENST00000372466",9,1755,"ENSG00000198088","NUP62CL","GO:0006810(transport);GO:0015031(protein transport);GO:0017056(structural constituent of nuclear pore);GO:0005643(nuclear pore);GO:0005515(protein binding);GO:0006606(protein import into nucleus);GO:0044613(nuclear pore central transport channel);GO:0005487(nucleocytoplasmic transporter activity);GO:0005543(phospholipid binding);GO:0071426(ribonucleoprotein complex export from nucleus)","NA","NA","NA","nucleoporin 62 C-terminal like [Source:HGNC Symbol;Acc:HGNC:25960]",{"v":0.060142,"d":"0.06"},{"v":0.094615,"d":"0.09"},{"v":0.635649738413571,"d":"0.64"},{"v":-0.653696077571782,"d":"-0.65"},1,1,"down","no"]
[190915,0,"chr9","+",69121264,69255208,"ENST00000453658",22,4129,"ENSG00000119139","TJP2","GO:0005923(bicellular tight junction);GO:0005634(nucleus);GO:0016020(membrane);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0030054(cell junction);GO:0005515(protein binding);GO:0005654(nucleoplasm);GO:0045296(cadherin binding);GO:0005912(adherens junction);GO:0046037(GMP metabolic process);GO:0046710(GDP metabolic process);GO:0019904(protein domain specific binding);GO:0030674(protein binding, bridging);GO:0035329(hippo signaling);GO:0004385(guanylate kinase activity);GO:0050892(intestinal absorption);GO:0090557(establishment of endothelial intestinal barrier);GO:0090559(regulation of membrane permeability);GO:0008022(protein C-terminus binding);GO:0010033(response to organic substance);GO:0071847(TNFSF11-mediated signaling pathway);GO:2001205(negative regulation of osteoclast development);GO:0005911(cell-cell junction);GO:0070160(occluding junction)","04530(Tight junction);05110(Vibrio cholerae infection)","K06098","NA","tight junction protein 2 [Source:HGNC Symbol;Acc:HGNC:11828]",{"v":0.064083,"d":"0.06"},0,"inf","inf",1,1,"up","no"]
[191150,0,"chr9","+",76459222,76502469,"ENST00000480311",3,461,"ENSG00000187210","GCNT1","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016740(transferase activity);GO:0016757(transferase activity, transferring glycosyl groups);GO:0005794(Golgi apparatus);GO:0005515(protein binding);GO:0000139(Golgi membrane);GO:0006486(protein glycosylation);GO:0008375(acetylglucosaminyltransferase activity);GO:0005802(trans-Golgi network);GO:0031985(Golgi cisterna);GO:0016266(O-glycan processing);GO:0003829(beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity);GO:0009101(glycoprotein biosynthetic process);GO:0050901(leukocyte tethering or rolling);GO:0060352(cell adhesion molecule production);GO:0032868(response to insulin);GO:0048729(tissue morphogenesis);GO:0060993(kidney morphogenesis);GO:0005615(extracellular space)","00512(Mucin type O-glycan biosynthesis)","NA","NA","glucosaminyl (N-acetyl) transferase 1, core 2 [Source:HGNC Symbol;Acc:HGNC:4203]",{"v":0.324664,"d":"0.32"},{"v":0.276414,"d":"0.28"},{"v":1.1745570050721,"d":"1.17"},{"v":0.232116733732472,"d":"0.23"},1,1,"up","no"]
[168157,0,"chr6","+",107028569,107051335,"ENST00000625458",5,1146,"ENSG00000130349","C6orf203","GO:0005739(mitochondrion)","NA","NA","NA","chromosome 6 open reading frame 203 [Source:HGNC Symbol;Acc:HGNC:17971]",{"v":0.454384,"d":"0.45"},{"v":0.394486,"d":"0.39"},{"v":1.15183808804368,"d":"1.15"},{"v":0.203937933799913,"d":"0.20"},1,1,"up","no"]
[136132,0,"chr3","-",49076707,49094230,"ENST00000450685",2,426,"MSTRG.10922","QRICH1","GO:0005654(nucleoplasm);GO:0005515(protein binding);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0005737(cytoplasm);GO:0003674(molecular_function);GO:0008150(biological_process);GO:0005575(cellular_component);GO:0000981(RNA polymerase II transcription factor activity, sequence-specific DNA binding);GO:0007275(multicellular organism development);GO:0003677(DNA binding);GO:0007010(cytoskeleton organization);GO:0022604(regulation of cell morphogenesis);GO:0042981(regulation of apoptotic process)","NA","NA","NA","glutamine rich 1 [Source:HGNC Symbol;Acc:HGNC:24713]",0,{"v":2.780427,"d":"2.78"},"-inf","-inf",1,1,"down","no"]
[186939,0,"chr8","+",124483345,124486234,"ENST00000517684",2,467,"MSTRG.14548","RNF139","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0016740(transferase activity);GO:0016567(protein ubiquitination);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0016874(ligase activity);GO:0005515(protein binding);GO:0044322(endoplasmic reticulum quality control compartment);GO:0061630(ubiquitin protein ligase activity);GO:0043161(proteasome-mediated ubiquitin-dependent protein catabolic process);GO:0031648(protein destabilization);GO:0008285(negative regulation of cell proliferation);GO:0004872(receptor activity);GO:0017148(negative regulation of translation);GO:0000209(protein polyubiquitination);GO:0002020(protease binding);GO:0004842(ubiquitin-protein transferase activity);GO:1904264(ubiquitin protein ligase activity involved in ERAD pathway);GO:1904380(endoplasmic reticulum mannose trimming);GO:0030433(ubiquitin-dependent ERAD pathway);GO:0036503(ERAD pathway);GO:2000060(positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process);GO:0031396(regulation of protein ubiquitination);GO:0060628(regulation of ER to Golgi vesicle-mediated transport);GO:0036513(Derlin-1 retrotranslocation complex);GO:0019787(ubiquitin-like protein transferase activity);GO:0070613(regulation of protein processing)","NA","NA","NA","ring finger protein 139 [Source:HGNC Symbol;Acc:HGNC:17023]",0,0,1,0,1,1,"no","no"]
[23926,0,"chr10","+",120456954,120589855,"ENST00000398250",7,1521,"ENSG00000203805","PLPP4","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0008195(phosphatidate phosphatase activity);GO:0046839(phospholipid dephosphorylation);GO:0016787(hydrolase activity);GO:0038096(Fc-gamma receptor signaling pathway involved in phagocytosis);GO:0005886(plasma membrane);GO:0042802(identical protein binding);GO:0005887(integral component of plasma membrane);GO:0007165(signal transduction);GO:0006644(phospholipid metabolic process)","00561(Glycerolipid metabolism);00564(Glycerophospholipid metabolism)","K18693","EC:3.1.3.81;EC:3.1.3.4","phospholipid phosphatase 4 [Source:HGNC Symbol;Acc:HGNC:23531]",{"v":0.033795,"d":"0.03"},{"v":0.020213,"d":"0.02"},{"v":1.67194379854549,"d":"1.67"},{"v":0.741526352847951,"d":"0.74"},1,1,"up","no"]
[38833,0,"chr12","-",10372416,10382182,"ENST00000540267",5,1787,"MSTRG.3171","KLRK1","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0030246(carbohydrate binding);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0030154(cell differentiation);GO:0002376(immune system process);GO:0045087(innate immune response);GO:0032394(MHC class Ib receptor activity);GO:0042288(MHC class I protein binding);GO:0042803(protein homodimerization activity);GO:0002223(stimulatory C-type lectin receptor signaling pathway);GO:0030101(natural killer cell activation);GO:0032729(positive regulation of interferon-gamma production);GO:0045429(positive regulation of nitric oxide biosynthetic process);GO:0045954(positive regulation of natural killer cell mediated cytotoxicity);GO:0050830(defense response to Gram-positive bacterium);GO:0071222(cellular response to lipopolysaccharide);GO:0009897(external side of plasma membrane);GO:0009986(cell surface);GO:0002250(adaptive immune response);GO:0050776(regulation of immune response);GO:0004872(receptor activity);GO:0005887(integral component of plasma membrane);GO:0007165(signal transduction);GO:0031295(T cell costimulation);GO:0034260(negative regulation of GTPase activity);GO:0042267(natural killer cell mediated cytotoxicity);GO:2000502(negative regulation of natural killer cell chemotaxis)","04650(Natural killer cell mediated cytotoxicity);05144(Malaria)","NA","NA","killer cell lectin like receptor K1 [Source:HGNC Symbol;Acc:HGNC:18788]",{"v":0.283285,"d":"0.28"},{"v":0.180499,"d":"0.18"},{"v":1.56945467841927,"d":"1.57"},{"v":0.650263368414244,"d":"0.65"},1,1,"up","no"]
[183479,0,"chr8","-",42439467,42460168,"ENST00000522401",3,577,"ENSG00000168575","SLC20A2","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0015293(symporter activity);GO:0055085(transmembrane transport);GO:0006811(ion transport);GO:0005886(plasma membrane);GO:0006814(sodium ion transport);GO:0035725(sodium ion transmembrane transport);GO:0046718(viral entry into host cell);GO:0070062(extracellular exosome);GO:0005315(inorganic phosphate transmembrane transporter activity);GO:0006817(phosphate ion transport);GO:0035435(phosphate ion transmembrane transport);GO:0016032(viral process);GO:0005887(integral component of plasma membrane);GO:0004872(receptor activity);GO:0005436(sodium:phosphate symporter activity);GO:0001618(virus receptor activity);GO:0015321(sodium-dependent phosphate transmembrane transporter activity);GO:0015319(sodium:inorganic phosphate symporter activity);GO:0044341(sodium-dependent phosphate transport)","NA","NA","NA","solute carrier family 20 member 2 [Source:HGNC Symbol;Acc:HGNC:10947]",0,0,1,0,1,1,"no","no"]
[48445,0,"chr12","-",130396137,130517865,"ENST00000261655",19,6321,"ENSG00000060709","RIMBP2","GO:0016020(membrane);GO:0005886(plasma membrane);GO:0030054(cell junction);GO:0045202(synapse);GO:0010923(negative regulation of phosphatase activity)","NA","NA","NA","RIMS binding protein 2 [Source:HGNC Symbol;Acc:HGNC:30339]",{"v":0.060036,"d":"0.06"},{"v":0.024107,"d":"0.02"},{"v":2.49039698013025,"d":"2.49"},{"v":1.31637573250046,"d":"1.32"},1,1,"up","no"]
[171621,0,"chr7","+",6009290,6015251,"ENST00000415999",3,777,"MSTRG.13477","AIMP2","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0006412(translation);GO:0005829(cytosol);GO:0032947(protein complex scaffold);GO:0006461(protein complex assembly);GO:0008285(negative regulation of cell proliferation);GO:0031398(positive regulation of protein ubiquitination);GO:0060510(Type II pneumocyte differentiation);GO:1901216(positive regulation of neuron death);GO:1903632(positive regulation of aminoacyl-tRNA ligase activity);GO:0017101(aminoacyl-tRNA synthetase multienzyme complex);GO:0005515(protein binding);GO:0006915(apoptotic process);GO:0007275(multicellular organism development);GO:0030154(cell differentiation);GO:0006418(tRNA aminoacylation for protein translation)","NA","NA","NA","aminoacyl tRNA synthetase complex interacting multifunctional protein 2 [Source:HGNC Symbol;Acc:HGNC:20609]",{"v":0.087734,"d":"0.09"},{"v":0.058718,"d":"0.06"},{"v":1.49415852038557,"d":"1.49"},{"v":0.579333216696169,"d":"0.58"},1,1,"up","no"]
[55519,0,"chr14","-",59472617,59484430,"ENST00000247194",5,1527,"MSTRG.4453","L3HYPDH","GO:0016829(lyase activity);GO:0008152(metabolic process);GO:0016836(hydro-lyase activity);GO:0050346(trans-L-3-hydroxyproline dehydratase activity)","00330(Arginine and proline metabolism)","K18384","EC:4.2.1.77","trans-L-3-hydroxyproline dehydratase [Source:HGNC Symbol;Acc:HGNC:20488]",{"v":0.467109,"d":"0.47"},{"v":0.375961,"d":"0.38"},{"v":1.24244004032333,"d":"1.24"},{"v":0.313176229561837,"d":"0.31"},1,1,"up","no"]
[94592,0,"chr19","-",2233964,2236239,"ENST00000586497",4,573,"MSTRG.7633","PLEKHJ1","GO:0005829(cytosol);GO:0042147(retrograde transport, endosome to Golgi);GO:0007032(endosome organization);GO:0005802(trans-Golgi network);GO:0005769(early endosome);GO:0055037(recycling endosome);GO:0001881(receptor recycling)","NA","NA","NA","pleckstrin homology domain containing J1 [Source:HGNC Symbol;Acc:HGNC:18211]",0,0,1,0,1,1,"no","no"]
[99762,0,"chr19","+",33798386,33814243,"ENST00000430256",6,2555,"ENSG00000153885","KCTD15","GO:0051260(protein homooligomerization);GO:0005515(protein binding);GO:0007275(multicellular organism development);GO:0042802(identical protein binding)","NA","NA","NA","potassium channel tetramerization domain containing 15 [Source:HGNC Symbol;Acc:HGNC:23297]",0,0,1,0,1,1,"no","no"]
[47737,0,"chr12","+",121947669,121959089,"ENST00000543211",5,4675,"MSTRG.3814","WDR66","GO:0005737(cytoplasm);GO:0031514(motile cilium);GO:0005856(cytoskeleton);GO:0042995(cell projection);GO:0003341(cilium movement);GO:0005930(axoneme);GO:0001536(radial spoke stalk)","NA","NA","NA","WD repeat domain 66 [Source:HGNC Symbol;Acc:HGNC:28506]",0,0,1,0,1,1,"no","no"]
[128264,0,"chr22","-",17207206,17221854,"ENST00000441548",3,581,"MSTRG.10105","ADA2","GO:0005615(extracellular space);GO:0046872(metal ion binding);GO:0016787(hydrolase activity);GO:0008083(growth factor activity);GO:0008270(zinc ion binding);GO:0042803(protein homodimerization activity);GO:0019239(deaminase activity);GO:0005576(extracellular region);GO:0007275(multicellular organism development);GO:0004000(adenosine deaminase activity);GO:0006154(adenosine catabolic process);GO:0008201(heparin binding);GO:0044267(cellular protein metabolic process);GO:0043312(neutrophil degranulation);GO:0035578(azurophil granule lumen);GO:0043394(proteoglycan binding);GO:0043103(hypoxanthine salvage);GO:0031685(adenosine receptor binding);GO:0046103(inosine biosynthetic process)","00230(Purine metabolism)","NA","NA","adenosine deaminase 2 [Source:HGNC Symbol;Acc:HGNC:1839]",{"v":0.497205,"d":"0.50"},{"v":0.925564,"d":"0.93"},{"v":0.537191377365585,"d":"0.54"},{"v":-0.896491947105901,"d":"-0.90"},1,1,"down","no"]
[49231,0,"chr13","+",26400073,26405238,"ENST00000480323",4,1996,"ENSG00000132964","CDK8","GO:0004672(protein kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0005634(nucleus);GO:0000166(nucleotide binding);GO:0004674(protein serine/threonine kinase activity);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0005515(protein binding);GO:0005654(nucleoplasm);GO:0043234(protein complex);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0006367(transcription initiation from RNA polymerase II promoter);GO:0007346(regulation of mitotic cell cycle);GO:0005730(nucleolus);GO:0016592(mediator complex);GO:0004693(cyclin-dependent protein serine/threonine kinase activity);GO:0008353(RNA polymerase II carboxy-terminal domain kinase activity)","NA","NA","NA","cyclin dependent kinase 8 [Source:HGNC Symbol;Acc:HGNC:1779]",{"v":0.28567,"d":"0.29"},{"v":0.114054,"d":"0.11"},{"v":2.50469076051695,"d":"2.50"},{"v":1.32463249331727,"d":"1.32"},1,1,"up","no"]
[67944,0,"chr16","+",1665776,1667417,"ENST00000467286",3,664,"ENSG00000007545","CRAMP1","GO:0005634(nucleus);GO:0003677(DNA binding);GO:0003682(chromatin binding)","NA","NA","NA","cramped chromatin regulator homolog 1 [Source:HGNC Symbol;Acc:HGNC:14122]",0,{"v":0.005317,"d":"0.01"},"-inf","-inf",1,1,"down","no"]
[169722,0,"chr6","+",139271362,139287307,"ENST00000441249",4,914,"MSTRG.13314","AL158850.1","NA","NA","NA","NA","NA",{"v":0.056239,"d":"0.06"},{"v":0.395697,"d":"0.40"},{"v":0.142126425017122,"d":"0.14"},{"v":-2.81475328065232,"d":"-2.81"},1,1,"down","no"]
[147116,0,"chr4","+",44678494,44689409,"ENST00000513775",9,1219,"ENSG00000151806","GUF1","GO:0016020(membrane);GO:0006412(translation);GO:0005525(GTP binding);GO:0000166(nucleotide binding);GO:0016787(hydrolase activity);GO:0005743(mitochondrial inner membrane);GO:0003924(GTPase activity);GO:0005739(mitochondrion);GO:0005759(mitochondrial matrix);GO:0043022(ribosome binding);GO:0045727(positive regulation of translation)","NA","NA","NA","GUF1 homolog, GTPase [Source:HGNC Symbol;Acc:HGNC:25799]",{"v":0.156352,"d":"0.16"},{"v":0.043757,"d":"0.04"},{"v":3.57318828987362,"d":"3.57"},{"v":1.83721193903083,"d":"1.84"},1,1,"up","no"]
[1444,0,"chr1","+",10474982,10623286,"ENST00000491661",6,637,"ENSG00000142655","PEX14","GO:0006810(transport);GO:0005634(nucleus);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0015031(protein transport);GO:0001650(fibrillar center);GO:0005515(protein binding);GO:0005777(peroxisome);GO:0008017(microtubule binding);GO:0005778(peroxisomal membrane);GO:0003714(transcription corepressor activity);GO:0005622(intracellular);GO:0043234(protein complex);GO:0005102(receptor binding);GO:0047485(protein N-terminus binding);GO:0043433(negative regulation of sequence-specific DNA binding transcription factor activity);GO:0045892(negative regulation of transcription, DNA-templated);GO:0007031(peroxisome organization);GO:0016558(protein import into peroxisome matrix);GO:1990429(peroxisomal importomer complex);GO:0032091(negative regulation of protein binding);GO:0048487(beta-tubulin binding);GO:0006461(protein complex assembly);GO:0051260(protein homooligomerization);GO:0034453(microtubule anchoring);GO:0016561(protein import into peroxisome matrix, translocation);GO:0036250(peroxisome transport along microtubule);GO:0044721(protein import into peroxisome matrix, substrate release);GO:1901094(negative regulation of protein homotetramerization);GO:0016560(protein import into peroxisome matrix, docking)","04146(Peroxisome)","NA","NA","peroxisomal biogenesis factor 14 [Source:HGNC Symbol;Acc:HGNC:8856]",{"v":0.194918,"d":"0.19"},{"v":1.565158,"d":"1.57"},{"v":0.124535669881252,"d":"0.12"},{"v":-3.00536907235052,"d":"-3.01"},1,1,"down","no"]
[110831,0,"chr2","-",70607618,70768198,"ENST00000403045",21,3745,"ENSG00000075340","ADD2","GO:0030036(actin cytoskeleton organization);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0003779(actin binding);GO:0005886(plasma membrane);GO:0005856(cytoskeleton);GO:0031410(cytoplasmic vesicle);GO:0005516(calmodulin binding);GO:0005829(cytosol);GO:0055085(transmembrane transport);GO:0042803(protein homodimerization activity);GO:0046982(protein heterodimerization activity);GO:0032092(positive regulation of protein binding);GO:0006461(protein complex assembly);GO:0051015(actin filament binding);GO:0030507(spectrin binding);GO:0019901(protein kinase binding);GO:0051016(barbed-end actin filament capping);GO:0051017(actin filament bundle assembly);GO:0008290(F-actin capping protein complex);GO:0050900(leukocyte migration);GO:0050901(leukocyte tethering or rolling);GO:0044853(plasma membrane raft);GO:0005198(structural molecule activity);GO:0030097(hemopoiesis);GO:0014069(postsynaptic density)","NA","NA","NA","adducin 2 [Source:HGNC Symbol;Acc:HGNC:244]",{"v":0.008233,"d":"0.01"},0,"inf","inf",1,1,"up","no"]
[44080,0,"chr12","+",67294955,67297848,"ENST00000535146",3,560,"MSTRG.3536","CAND1","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005794(Golgi apparatus);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0016567(protein ubiquitination);GO:0005515(protein binding);GO:0030154(cell differentiation);GO:0005576(extracellular region);GO:0070062(extracellular exosome);GO:0043687(post-translational protein modification);GO:0043312(neutrophil degranulation);GO:0034774(secretory granule lumen);GO:1904813(ficolin-1-rich granule lumen);GO:0000151(ubiquitin ligase complex);GO:0043086(negative regulation of catalytic activity);GO:0006879(cellular iron ion homeostasis);GO:0031461(cullin-RING ubiquitin ligase complex);GO:0017025(TBP-class protein binding);GO:0010265(SCF complex assembly);GO:0045893(positive regulation of transcription, DNA-templated);GO:0045899(positive regulation of RNA polymerase II transcriptional preinitiation complex assembly)","NA","NA","NA","cullin associated and neddylation dissociated 1 [Source:HGNC Symbol;Acc:HGNC:30688]",{"v":0.142143,"d":"0.14"},{"v":0.01461,"d":"0.01"},{"v":9.72915811088296,"d":"9.73"},{"v":3.28231497028867,"d":"3.28"},1,1,"up","no"]
[58447,0,"chr14","+",100137106,100143863,"ENST00000553694",5,890,"MSTRG.4664","EVL","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0003779(actin binding);GO:0017124(SH3 domain binding);GO:0008154(actin polymerization or depolymerization);GO:0051289(protein homotetramerization);GO:0005856(cytoskeleton);GO:0042995(cell projection);GO:0005515(protein binding);GO:0007399(nervous system development);GO:0045010(actin nucleation);GO:0005925(focal adhesion);GO:0005829(cytosol);GO:0030027(lamellipodium);GO:0007411(axon guidance);GO:0051496(positive regulation of stress fiber assembly);GO:0009887(animal organ morphogenesis);GO:0007166(cell surface receptor signaling pathway);GO:0007015(actin filament organization);GO:0010633(negative regulation of epithelial cell migration);GO:1900028(negative regulation of ruffle assembly);GO:0005522(profilin binding);GO:0030838(positive regulation of actin filament polymerization)","NA","NA","NA","Enah/Vasp-like [Source:HGNC Symbol;Acc:HGNC:20234]",{"v":0.115225,"d":"0.12"},0,"inf","inf",1,1,"up","no"]
[174896,0,"chr7","-",73573879,73576748,"ENST00000469518",3,583,"ENSG00000106638","TBL2","GO:0003723(RNA binding);GO:0005783(endoplasmic reticulum);GO:0019901(protein kinase binding);GO:0042149(cellular response to glucose starvation);GO:0030176(integral component of endoplasmic reticulum membrane);GO:0071456(cellular response to hypoxia);GO:0031369(translation initiation factor binding);GO:0030968(endoplasmic reticulum unfolded protein response);GO:0051219(phosphoprotein binding)","NA","NA","NA","transducin beta like 2 [Source:HGNC Symbol;Acc:HGNC:11586]",0,0,1,0,1,1,"no","no"]
[37496,0,"chr12","-",2859488,2868581,"ENST00000535350",6,618,"MSTRG.3044","FOXM1","GO:0008284(positive regulation of cell proliferation);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:2000377(regulation of reactive oxygen species metabolic process);GO:0005634(nucleus);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0043565(sequence-specific DNA binding);GO:0005515(protein binding);GO:0006281(DNA repair);GO:0006974(cellular response to DNA damage stimulus);GO:0007049(cell cycle);GO:0045893(positive regulation of transcription, DNA-templated);GO:0005654(nucleoplasm);GO:0019901(protein kinase binding);GO:0000981(RNA polymerase II transcription factor activity, sequence-specific DNA binding);GO:0000086(G2/M transition of mitotic cell cycle);GO:0009653(anatomical structure morphogenesis);GO:0030154(cell differentiation);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0045892(negative regulation of transcription, DNA-templated);GO:0000977(RNA polymerase II regulatory region sequence-specific DNA binding);GO:0001227(transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding);GO:0051726(regulation of cell cycle);GO:0032873(negative regulation of stress-activated MAPK cascade);GO:0006978(DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator);GO:0046578(regulation of Ras protein signal transduction);GO:0071156(regulation of cell cycle arrest);GO:0090344(negative regulation of cell aging);GO:2000781(positive regulation of double-strand break repair)","04218(Cellular senescence)","NA","NA","forkhead box M1 [Source:HGNC Symbol;Acc:HGNC:3818]",0,{"v":0.070313,"d":"0.07"},"-inf","-inf",1,1,"down","no"]
[133768,0,"chr3","-",15560747,15601569,"ENST00000456194",16,1880,"MSTRG.10704","HACL1","GO:0043231(intracellular membrane-bounded organelle);GO:0046872(metal ion binding);GO:0000287(magnesium ion binding);GO:0003824(catalytic activity);GO:0016829(lyase activity);GO:0006631(fatty acid metabolic process);GO:0005515(protein binding);GO:0048037(cofactor binding);GO:0005777(peroxisome);GO:0042802(identical protein binding);GO:0030976(thiamine pyrophosphate binding);GO:0005102(receptor binding);GO:0005782(peroxisomal matrix);GO:0051259(protein oligomerization);GO:0001561(fatty acid alpha-oxidation);GO:0016830(carbon-carbon lyase activity);GO:0006629(lipid metabolic process)","04146(Peroxisome)","K12261","EC:4.1.-.-","2-hydroxyacyl-CoA lyase 1 [Source:HGNC Symbol;Acc:HGNC:17856]",0,0,1,0,1,1,"no","no"]
[124056,0,"chr20","+",45363200,45410610,"ENST00000419593",6,1313,"MSTRG.9768","SYS1-DBNDD2","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005829(cytosol);GO:0030173(integral component of Golgi membrane);GO:0005802(trans-Golgi network);GO:0000042(protein targeting to Golgi);GO:0006895(Golgi to endosome transport);GO:0043001(Golgi to plasma membrane protein transport)","NA","NA","NA","SYS1-DBNDD2 readthrough (NMD candidate) [Source:HGNC Symbol;Acc:HGNC:33535]",0,0,1,0,1,1,"no","no"]
[7926,0,"chr1","-",90860550,90862920,"ENST00000606898",2,879,"ENSG00000272094","AC091614.1","NA","NA","NA","NA","NA",{"v":0.017737,"d":"0.02"},{"v":0.04706,"d":"0.05"},{"v":0.376901827454314,"d":"0.38"},{"v":-1.4077393047859,"d":"-1.41"},1,1,"down","no"]
[64364,0,"chr15","+",72654738,72666394,"ENST00000421285",18,2134,"ENSG00000215186","GOLGA6B","GO:0005794(Golgi apparatus)","NA","NA","NA","golgin A6 family member B [Source:HGNC Symbol;Acc:HGNC:32205]",{"v":0.041727,"d":"0.04"},{"v":0.012126,"d":"0.01"},{"v":3.44111825828798,"d":"3.44"},{"v":1.78287747292754,"d":"1.78"},1,1,"up","no"]
[68419,0,"chr16","+",2520390,2528054,"ENST00000565963",4,844,"MSTRG.5548","AMDHD2","GO:0016787(hydrolase activity);GO:0016810(hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0005515(protein binding);GO:0005975(carbohydrate metabolic process);GO:0006044(N-acetylglucosamine metabolic process);GO:0005829(cytosol);GO:0006046(N-acetylglucosamine catabolic process);GO:0006048(UDP-N-acetylglucosamine biosynthetic process);GO:0019262(N-acetylneuraminate catabolic process);GO:0008448(N-acetylglucosamine-6-phosphate deacetylase activity)","00520(Amino sugar and nucleotide sugar metabolism)","NA","NA","amidohydrolase domain containing 2 [Source:HGNC Symbol;Acc:HGNC:24262]",{"v":9.7E-5,"d":"0.00"},{"v":0.021323,"d":"0.02"},{"v":0.004549078459879,"d":"0.00"},{"v":-7.78020996704677,"d":"-7.78"},1,1,"down","no"]
[32799,0,"chr11","-",72685070,72700088,"ENST00000455638",19,2683,"MSTRG.2689","ARAP1","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0043231(intracellular membrane-bounded organelle);GO:0046872(metal ion binding);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0007165(signal transduction);GO:0005794(Golgi apparatus);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0005096(GTPase activator activity);GO:0032580(Golgi cisterna membrane);GO:0051056(regulation of small GTPase mediated signal transduction);GO:0043547(positive regulation of GTPase activity);GO:0005547(phosphatidylinositol-3,4,5-trisphosphate binding);GO:0008360(regulation of cell shape);GO:0051491(positive regulation of filopodium assembly);GO:0051497(negative regulation of stress fiber assembly);GO:0045742(positive regulation of epidermal growth factor receptor signaling pathway);GO:0030037(actin filament reorganization involved in cell cycle);GO:0051270(regulation of cellular component movement);GO:0031702(type 1 angiotensin receptor binding);GO:0001921(positive regulation of receptor recycling);GO:0005802(trans-Golgi network);GO:0031410(cytoplasmic vesicle)","04144(Endocytosis)","NA","NA","ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1 [Source:HGNC Symbol;Acc:HGNC:16925]",0,0,1,0,1,1,"no","no"]
[39069,0,"chr12","+",12813316,12829979,"ENST00000352940",11,1698,"MSTRG.3211","DDX47","GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0006397(mRNA processing);GO:0008380(RNA splicing);GO:0005634(nucleus);GO:0016020(membrane);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0005730(nucleolus);GO:0016787(hydrolase activity);GO:0004386(helicase activity);GO:0005515(protein binding);GO:0006915(apoptotic process);GO:0006364(rRNA processing);GO:0005737(cytoplasm);GO:0005654(nucleoplasm);GO:0004004(ATP-dependent RNA helicase activity);GO:0010501(RNA secondary structure unwinding);GO:0008625(extrinsic apoptotic signaling pathway via death domain receptors)","NA","NA","NA","DEAD-box helicase 47 [Source:HGNC Symbol;Acc:HGNC:18682]",0,0,1,0,1,1,"no","no"]
[80591,0,"chr17","+",19378253,19383544,"ENST00000395602",7,3059,"ENSG00000166484","MAPK7","GO:0050728(negative regulation of inflammatory response);GO:0034115(negative regulation of heterotypic cell-cell adhesion);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0005634(nucleus);GO:2000352(negative regulation of endothelial cell apoptotic process);GO:0005737(cytoplasm);GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0005654(nucleoplasm);GO:0016740(transferase activity);GO:0004707(MAP kinase activity);GO:0016301(kinase activity);GO:0000165(MAPK cascade);GO:0016310(phosphorylation);GO:0005515(protein binding);GO:0007049(cell cycle);GO:0030154(cell differentiation);GO:0005829(cytosol);GO:0007165(signal transduction);GO:0016605(PML body);GO:0007411(axon guidance);GO:0071560(cellular response to transforming growth factor beta stimulus);GO:2001240(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand);GO:0051247(positive regulation of protein metabolic process);GO:0060761(negative regulation of response to cytokine stimulus);GO:0071363(cellular response to growth factor stimulus);GO:0071499(cellular response to laminar fluid shear stress);GO:0019933(cAMP-mediated signaling);GO:1902176(negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway);GO:0051019(mitogen-activated protein kinase binding);GO:0070301(cellular response to hydrogen peroxide);GO:0036003(positive regulation of transcription from RNA polymerase II promoter in response to stress);GO:0030821(negative regulation of cAMP catabolic process);GO:0051344(negative regulation of cyclic-nucleotide phosphodiesterase activity);GO:0005622(intracellular);GO:0018105(peptidyl-serine phosphorylation);GO:0043066(negative regulation of apoptotic process);GO:0043407(negative regulation of MAP kinase activity);GO:0045765(regulation of angiogenesis);GO:0051534(negative regulation of NFAT protein import into nucleus);GO:0070377(negative regulation of ERK5 cascade)","04010(MAPK signaling pathway);04540(Gap junction);04657(IL-17 signaling pathway);04912(GnRH signaling pathway);04921(Oxytocin signaling pathway);04722(Neurotrophin signaling pathway);05206(MicroRNAs in cancer);05418(Fluid shear stress and atherosclerosis)","K04464","EC:2.7.11.24","mitogen-activated protein kinase 7 [Source:HGNC Symbol;Acc:HGNC:6880]",{"v":0.718636,"d":"0.72"},0,"inf","inf",1,1,"up","no"]
[29691,0,"chr11","+",60378482,60394811,"ENST00000300184",7,1869,"ENSG00000166927","MS4A7","GO:0016020(membrane);GO:0016021(integral component of membrane)","NA","NA","NA","membrane spanning 4-domains A7 [Source:HGNC Symbol;Acc:HGNC:13378]",{"v":0.126078,"d":"0.13"},{"v":1.303553,"d":"1.30"},{"v":0.0967187371744762,"d":"0.10"},{"v":-3.37006078187105,"d":"-3.37"},1,1,"down","no"]
[175285,0,"chr7","-",75998545,76047980,"ENST00000451157",9,1570,"MSTRG.13741","STYXL1","GO:0005622(intracellular);GO:0016787(hydrolase activity);GO:0008138(protein tyrosine/serine/threonine phosphatase activity);GO:0006470(protein dephosphorylation);GO:0016311(dephosphorylation);GO:0004721(phosphoprotein phosphatase activity);GO:0035556(intracellular signal transduction)","NA","NA","NA","serine/threonine/tyrosine interacting like 1 [Source:HGNC Symbol;Acc:HGNC:18165]",{"v":0.03274,"d":"0.03"},0,"inf","inf",1,1,"up","no"]
[82732,0,"chr17","+",38870061,38919175,"ENST00000443937",8,1482,"MSTRG.6768","LASP1","GO:0005737(cytoplasm);GO:0006810(transport);GO:0046872(metal ion binding);GO:0034220(ion transmembrane transport);GO:0009967(positive regulation of signal transduction);GO:0003779(actin binding);GO:0006811(ion transport);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0015075(ion transmembrane transporter activity);GO:0051015(actin filament binding);GO:0005925(focal adhesion);GO:0030864(cortical actin cytoskeleton);GO:0045296(cadherin binding);GO:0070062(extracellular exosome);GO:0005938(cell cortex);GO:0005070(SH3/SH2 adaptor activity)","NA","NA","NA","LIM and SH3 protein 1 [Source:HGNC Symbol;Acc:HGNC:6513]",{"v":0.071507,"d":"0.07"},{"v":0.021817,"d":"0.02"},{"v":3.27758170234221,"d":"3.28"},{"v":1.71263174386268,"d":"1.71"},1,1,"up","no"]
[136256,0,"chr3","-",49305778,49314044,"ENST00000461553",4,544,"MSTRG.10931","USP4","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0005829(cytosol);GO:0004843(thiol-dependent ubiquitin-specific protease activity);GO:0016579(protein deubiquitination);GO:0016787(hydrolase activity);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0008233(peptidase activity);GO:0008234(cysteine-type peptidase activity);GO:0006508(proteolysis);GO:0006511(ubiquitin-dependent protein catabolic process);GO:0036459(thiol-dependent ubiquitinyl hydrolase activity);GO:0042802(identical protein binding);GO:0031647(regulation of protein stability);GO:0005764(lysosome);GO:0034394(protein localization to cell surface);GO:0031397(negative regulation of protein ubiquitination);GO:0000244(spliceosomal tri-snRNP complex assembly);GO:0031685(adenosine receptor binding)","NA","NA","NA","ubiquitin specific peptidase 4 [Source:HGNC Symbol;Acc:HGNC:12627]",{"v":0.060411,"d":"0.06"},0,"inf","inf",1,1,"up","no"]
[98094,0,"chr19","+",16829400,16880350,"ENST00000248054",19,5037,"MSTRG.7933","SIN3B","GO:0005634(nucleus);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0005515(protein binding);GO:0005654(nucleoplasm);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0019216(regulation of lipid metabolic process);GO:0016575(histone deacetylation);GO:0004407(histone deacetylase activity);GO:0001106(RNA polymerase II transcription corepressor activity);GO:0016580(Sin3 complex);GO:0003682(chromatin binding);GO:0003714(transcription corepressor activity);GO:0045892(negative regulation of transcription, DNA-templated);GO:0000805(X chromosome);GO:0000806(Y chromosome);GO:0001741(XY body);GO:0005737(cytoplasm);GO:0030849(autosome)","NA","NA","NA","SIN3 transcription regulator family member B [Source:HGNC Symbol;Acc:HGNC:19354]",0,0,1,0,1,1,"no","no"]
[168405,0,"chr6","-",110627002,110746201,"ENST00000463016",5,604,"MSTRG.13210","CDK19","GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0005634(nucleus);GO:0005829(cytosol);GO:0007346(regulation of mitotic cell cycle);GO:0004693(cyclin-dependent protein serine/threonine kinase activity);GO:0019899(enzyme binding);GO:0043065(positive regulation of apoptotic process);GO:0050729(positive regulation of inflammatory response);GO:0071222(cellular response to lipopolysaccharide)","NA","NA","NA","cyclin dependent kinase 19 [Source:HGNC Symbol;Acc:HGNC:19338]",0,0,1,0,1,1,"no","no"]
[55509,0,"chr14","+",59331430,59355284,"ENST00000554459",7,695,"MSTRG.4452","DAAM1","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005829(cytosol);GO:0003779(actin binding);GO:0031514(motile cilium);GO:0005886(plasma membrane);GO:0030036(actin cytoskeleton organization);GO:0005856(cytoskeleton);GO:0042995(cell projection);GO:0005515(protein binding);GO:0042802(identical protein binding);GO:0016043(cellular component organization);GO:0017048(Rho GTPase binding);GO:0001725(stress fiber);GO:0036064(ciliary basal body);GO:0060071(Wnt signaling pathway, planar cell polarity pathway)","04310(Wnt signaling pathway)","NA","NA","dishevelled associated activator of morphogenesis 1 [Source:HGNC Symbol;Acc:HGNC:18142]",{"v":0.423278,"d":"0.42"},{"v":0.152024,"d":"0.15"},{"v":2.78428406041151,"d":"2.78"},{"v":1.47730640646006,"d":"1.48"},1,1,"up","no"]
[194836,0,"chr9","-",136677027,136687365,"ENST00000470861",2,720,"MSTRG.15101","AGPAT2","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016740(transferase activity);GO:0016746(transferase activity, transferring acyl groups);GO:0006629(lipid metabolic process);GO:0008152(metabolic process);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0008654(phospholipid biosynthetic process);GO:0003841(1-acylglycerol-3-phosphate O-acyltransferase activity);GO:0016024(CDP-diacylglycerol biosynthetic process);GO:0005886(plasma membrane);GO:0043312(neutrophil degranulation);GO:0035579(specific granule membrane);GO:0006654(phosphatidic acid biosynthetic process);GO:0001819(positive regulation of cytokine production);GO:0001961(positive regulation of cytokine-mediated signaling pathway);GO:0006644(phospholipid metabolic process);GO:0008544(epidermis development);GO:0042493(response to drug)","00561(Glycerolipid metabolism);00564(Glycerophospholipid metabolism);04072(Phospholipase D signaling pathway);04975(Fat digestion and absorption)","NA","NA","1-acylglycerol-3-phosphate O-acyltransferase 2 [Source:HGNC Symbol;Acc:HGNC:325]",{"v":0.498642,"d":"0.50"},{"v":0.091794,"d":"0.09"},{"v":5.43218511013792,"d":"5.43"},{"v":2.44153264249276,"d":"2.44"},1,1,"up","no"]
[87637,0,"chr17","-",74256896,74262020,"ENST00000583018",2,513,"MSTRG.7174","AC100786.1","NA","NA","NA","NA","NA",0,{"v":0.03752,"d":"0.04"},"-inf","-inf",1,1,"down","no"]
[101139,0,"chr19","+",38899980,38908893,"ENST00000509705",5,2200,"MSTRG.8123","NFKBIB","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005515(protein binding);GO:0005829(cytosol);GO:0003713(transcription coactivator activity);GO:0004871(signal transducer activity);GO:0007165(signal transduction);GO:0051092(positive regulation of NF-kappaB transcription factor activity);GO:0006351(transcription, DNA-templated);GO:0071222(cellular response to lipopolysaccharide)","04621(NOD-like receptor signaling pathway);04622(RIG-I-like receptor signaling pathway);04623(Cytosolic DNA-sensing pathway);04660(T cell receptor signaling pathway);04658(Th1 and Th2 cell differentiation);04659(Th17 cell differentiation);04662(B cell receptor signaling pathway);04062(Chemokine signaling pathway);04920(Adipocytokine signaling pathway);04722(Neurotrophin signaling pathway);05131(Shigellosis);05162(Measles);05164(Influenza A);05168(Herpes simplex infection);05169(Epstein-Barr virus infection);05145(Toxoplasmosis);05140(Leishmaniasis)","K02581","NA","NFKB inhibitor beta [Source:HGNC Symbol;Acc:HGNC:7798]",{"v":0.16096,"d":"0.16"},{"v":0.337073,"d":"0.34"},{"v":0.477522673130153,"d":"0.48"},{"v":-1.06635885988376,"d":"-1.07"},1,1,"down","no"]
[40190,0,"chr12","+",31729117,31731204,"ENST00000619086",1,2088,"ENSG00000276900","AC023157.3","NA","NA","NA","NA","NA",0,{"v":2.756296,"d":"2.76"},"-inf","-inf",1,1,"down","no"]
[11902,0,"chr1","-",155946856,155951748,"ENST00000470541",5,1877,"MSTRG.1052","ARHGEF2","GO:0071356(cellular response to tumor necrosis factor);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0046872(metal ion binding);GO:0035556(intracellular signal transduction);GO:0005794(Golgi apparatus);GO:0051301(cell division);GO:0008270(zinc ion binding);GO:0005886(plasma membrane);GO:0005089(Rho guanyl-nucleotide exchange factor activity);GO:0035023(regulation of Rho protein signal transduction);GO:0043547(positive regulation of GTPase activity);GO:0005856(cytoskeleton);GO:0042995(cell projection);GO:0005515(protein binding);GO:0007049(cell cycle);GO:0030054(cell junction);GO:0005874(microtubule);GO:0031410(cytoplasmic vesicle);GO:0006886(intracellular protein transport);GO:0002376(immune system process);GO:0045087(innate immune response);GO:0005925(focal adhesion);GO:0005085(guanyl-nucleotide exchange factor activity);GO:0008017(microtubule binding);GO:0005819(spindle);GO:0005923(bicellular tight junction);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0005829(cytosol);GO:0051056(regulation of small GTPase mediated signal transduction);GO:0032587(ruffle membrane);GO:0043234(protein complex);GO:0042127(regulation of cell proliferation);GO:0051092(positive regulation of NF-kappaB transcription factor activity);GO:0031982(vesicle);GO:0007015(actin filament organization);GO:0043065(positive regulation of apoptotic process);GO:1902042(negative regulation of extrinsic apoptotic signaling pathway via death domain receptors);GO:0050731(positive regulation of peptidyl-tyrosine phosphorylation);GO:0017048(Rho GTPase binding);GO:0071225(cellular response to muramyl dipeptide);GO:0008134(transcription factor binding);GO:0007026(negative regulation of microtubule depolymerization);GO:0030676(Rac guanyl-nucleotide exchange factor activity);GO:0032760(positive regulation of tumor necrosis factor production);GO:0048365(Rac GTPase binding);GO:0071474(cellular hyperosmotic response);GO:1902219(negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress);GO:0000902(cell morphogenesis);GO:0060546(negative regulation of necroptotic process);GO:0032755(positive regulation of interleukin-6 production);GO:0000132(establishment of mitotic spindle orientation);GO:0050768(negative regulation of neurogenesis);GO:0071802(negative regulation of podosome assembly);GO:0002102(podosome);GO:0014069(postsynaptic density);GO:0043025(neuronal cell body);GO:0043198(dendritic shaft);GO:0005622(intracellular)","04530(Tight junction);05418(Fluid shear stress and atherosclerosis);05130(Pathogenic Escherichia coli infection)","NA","NA","Rho/Rac guanine nucleotide exchange factor 2 [Source:HGNC Symbol;Acc:HGNC:682]",0,{"v":0.609465,"d":"0.61"},"-inf","-inf",1,1,"down","no"]
[69431,0,"chr16","+",8797842,8848051,"ENST00000562318",7,931,"MSTRG.5640","PMM2","GO:0005737(cytoplasm);GO:0016853(isomerase activity);GO:0005634(nucleus);GO:0005829(cytosol);GO:0004615(phosphomannomutase activity);GO:0009298(GDP-mannose biosynthetic process);GO:0005515(protein binding);GO:0043025(neuronal cell body);GO:0070062(extracellular exosome);GO:0006013(mannose metabolic process);GO:0006486(protein glycosylation);GO:0006487(protein N-linked glycosylation);GO:0045047(protein targeting to ER)","00051(Fructose and mannose metabolism);00520(Amino sugar and nucleotide sugar metabolism)","NA","NA","phosphomannomutase 2 [Source:HGNC Symbol;Acc:HGNC:9115]",{"v":3.312062,"d":"3.31"},0,"inf","inf",1,1,"up","no"]
[62169,0,"chr15","+",45587353,45606486,"ENST00000569076",5,557,"MSTRG.5049","BLOC1S6","GO:0005737(cytoplasm);GO:0016020(membrane);GO:1904115(axon cytoplasm);GO:0042803(protein homodimerization activity);GO:0005515(protein binding);GO:0098793(presynapse);GO:0042802(identical protein binding);GO:0005829(cytosol);GO:0051015(actin filament binding);GO:0019898(extrinsic component of membrane);GO:0019905(syntaxin binding);GO:0031201(SNARE complex);GO:0008089(anterograde axonal transport);GO:0032438(melanosome organization);GO:0048490(anterograde synaptic vesicle transport);GO:0031175(neuron projection development);GO:0030133(transport vesicle);GO:0016081(synaptic vesicle docking);GO:0031083(BLOC-1 complex);GO:0035646(endosome to melanosome transport);GO:0032402(melanosome transport);GO:0050942(positive regulation of pigment cell differentiation);GO:0007596(blood coagulation);GO:0030318(melanocyte differentiation);GO:0032816(positive regulation of natural killer cell activation);GO:0033299(secretion of lysosomal enzymes);GO:0043473(pigmentation);GO:0061025(membrane fusion);GO:0005768(endosome)","NA","NA","NA","biogenesis of lysosomal organelles complex 1 subunit 6 [Source:HGNC Symbol;Acc:HGNC:8549]",0,0,1,0,1,1,"no","no"]
[185138,0,"chr8","+",85187685,85214490,"ENST00000521429",8,1551,"MSTRG.14421","E2F5","GO:0005634(nucleus);GO:0005730(nucleolus);GO:0046983(protein dimerization activity);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0001650(fibrillar center);GO:0005667(transcription factor complex);GO:0051726(regulation of cell cycle);GO:0005515(protein binding);GO:0005654(nucleoplasm);GO:0030030(cell projection organization);GO:0008134(transcription factor binding);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0009887(animal organ morphogenesis);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0016021(integral component of membrane)","04350(TGF-beta signaling pathway);04110(Cell cycle);04218(Cellular senescence)","NA","NA","E2F transcription factor 5 [Source:HGNC Symbol;Acc:HGNC:3119]",0,{"v":0.00064,"d":"0.00"},"-inf","-inf",1,1,"down","no"]
[24545,0,"chr10","-",133355203,133357737,"ENST00000368551",6,628,"ENSG00000148803","FUOM","GO:0016853(isomerase activity);GO:0005829(cytosol);GO:0016857(racemase and epimerase activity, acting on carbohydrates and derivatives);GO:0042806(fucose binding);GO:0048029(monosaccharide binding);GO:0005996(monosaccharide metabolic process);GO:0006004(fucose metabolic process);GO:0036065(fucosylation);GO:0045665(negative regulation of neuron differentiation);GO:0060180(female mating behavior)","NA","NA","NA","fucose mutarotase [Source:HGNC Symbol;Acc:HGNC:24733]",0,{"v":0.12012,"d":"0.12"},"-inf","-inf",1,1,"down","no"]
[120974,0,"chr2","-",241072169,241102332,"ENST00000464344",5,3993,"MSTRG.9520","MTERF4","GO:0003723(RNA binding);GO:0005829(cytosol);GO:0006355(regulation of transcription, DNA-templated);GO:0005739(mitochondrion);GO:0003690(double-stranded DNA binding);GO:0006364(rRNA processing);GO:0005515(protein binding);GO:0005759(mitochondrial matrix);GO:0003727(single-stranded RNA binding);GO:0008380(RNA splicing);GO:0031167(rRNA methylation);GO:0032502(developmental process);GO:0019843(rRNA binding);GO:0042255(ribosome assembly);GO:0005762(mitochondrial large ribosomal subunit);GO:0006390(transcription from mitochondrial promoter);GO:0006626(protein targeting to mitochondrion);GO:0007507(heart development);GO:0043010(camera-type eye development)","NA","NA","NA","mitochondrial transcription termination factor 4 [Source:HGNC Symbol;Acc:HGNC:28785]",{"v":0.16118,"d":"0.16"},{"v":0.036466,"d":"0.04"},{"v":4.42000767838535,"d":"4.42"},{"v":2.14404887585174,"d":"2.14"},1,1,"up","no"]
[117171,0,"chr2","+",187003274,187554393,"ENST00000412276",7,829,"ENSG00000224063","AC007319.1","NA","NA","NA","NA","NA",0,{"v":0.022197,"d":"0.02"},"-inf","-inf",1,1,"down","no"]
[6101,0,"chr1","-",52445787,52553082,"ENST00000528642",23,3854,"MSTRG.566","ZCCHC11","GO:0003676(nucleic acid binding);GO:0008270(zinc ion binding);GO:0005730(nucleolus);GO:0005829(cytosol);GO:0016779(nucleotidyltransferase activity);GO:0050265(RNA uridylyltransferase activity);GO:0001816(cytokine production);GO:0010586(miRNA metabolic process);GO:0031123(RNA 3'-end processing);GO:0031664(regulation of lipopolysaccharide-mediated signaling pathway);GO:0032088(negative regulation of NF-kappaB transcription factor activity);GO:0032755(positive regulation of interleukin-6 production);GO:0070102(interleukin-6-mediated signaling pathway);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0003723(RNA binding);GO:0046872(metal ion binding);GO:0016740(transferase activity);GO:0005615(extracellular space);GO:0031047(gene silencing by RNA);GO:0005515(protein binding);GO:0070062(extracellular exosome);GO:0000289(nuclear-transcribed mRNA poly(A) tail shortening);GO:0019827(stem cell population maintenance);GO:0031054(pre-miRNA processing);GO:0010587(miRNA catabolic process)","NA","NA","NA","zinc finger CCHC-type containing 11 [Source:HGNC Symbol;Acc:HGNC:28981]",0,0,1,0,1,1,"no","no"]
[32021,0,"chr11","-",67467299,67469236,"ENST00000541598",3,575,"ENSG00000172663","TMEM134","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0048471(perinuclear region of cytoplasm);GO:0005515(protein binding)","NA","NA","NA","transmembrane protein 134 [Source:HGNC Symbol;Acc:HGNC:26142]",{"v":1.7E-5,"d":"0.00"},{"v":0.015613,"d":"0.02"},{"v":0.00108883622622174,"d":"0.00"},{"v":-9.84299731259639,"d":"-9.84"},1,1,"down","no"]
[199254,0,"chrX","-",107775118,107776258,"ENST00000506724",2,521,"MSTRG.15396","TSC22D3","GO:0006355(regulation of transcription, DNA-templated);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0034220(ion transmembrane transport);GO:0070236(negative regulation of activation-induced cell death of T cells);GO:0043426(MRF binding);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0006970(response to osmotic stress);GO:0048642(negative regulation of skeletal muscle tissue development)","NA","NA","NA","TSC22 domain family member 3 [Source:HGNC Symbol;Acc:HGNC:3051]",0,0,1,0,1,1,"no","no"]
[46633,0,"chr12","+",110614124,110629282,"ENST00000546643",3,926,"MSTRG.3721","TCTN1","GO:0005737(cytoplasm);GO:0005856(cytoskeleton);GO:0042995(cell projection);GO:0005576(extracellular region);GO:0007275(multicellular organism development);GO:0060271(cilium assembly);GO:0005829(cytosol);GO:0030030(cell projection organization);GO:0097711(ciliary basal body docking);GO:0036038(MKS complex);GO:0001701(in utero embryonic development);GO:0001841(neural tube formation);GO:0008589(regulation of smoothened signaling pathway);GO:0021523(somatic motor neuron differentiation);GO:0021537(telencephalon development);GO:0021904(dorsal/ventral neural tube patterning);GO:0021956(central nervous system interneuron axonogenesis);GO:1904491(protein localization to ciliary transition zone);GO:0005615(extracellular space);GO:0016020(membrane);GO:0035869(ciliary transition zone)","NA","NA","NA","tectonic family member 1 [Source:HGNC Symbol;Acc:HGNC:26113]",0,{"v":0.091768,"d":"0.09"},"-inf","-inf",1,1,"down","no"]
[4456,0,"chr1","-",37979465,37980789,"ENST00000488934",2,273,"MSTRG.433","SF3A3","GO:0005634(nucleus);GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0006397(mRNA processing);GO:0008380(RNA splicing);GO:0016607(nuclear speck);GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0005654(nucleoplasm);GO:0005515(protein binding);GO:0005681(spliceosomal complex);GO:0000398(mRNA splicing, via spliceosome);GO:0000375(RNA splicing, via transesterification reactions);GO:0071013(catalytic step 2 spliceosome);GO:0000389(mRNA 3'-splice site recognition)","03040(Spliceosome)","NA","NA","splicing factor 3a subunit 3 [Source:HGNC Symbol;Acc:HGNC:10767]",0,0,1,0,1,1,"no","no"]
[1517,0,"chr1","-",11068645,11073026,"ENST00000469634",3,2361,"MSTRG.151","EXOSC10","GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0006396(RNA processing);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005730(nucleolus);GO:0005829(cytosol);GO:0016787(hydrolase activity);GO:0006139(nucleobase-containing compound metabolic process);GO:0003824(catalytic activity);GO:0005622(intracellular);GO:0090305(nucleic acid phosphodiester bond hydrolysis);GO:0005515(protein binding);GO:0000166(nucleotide binding);GO:0004527(exonuclease activity);GO:0004518(nuclease activity);GO:0008408(3'-5' exonuclease activity);GO:0044237(cellular metabolic process);GO:0006364(rRNA processing);GO:0000956(nuclear-transcribed mRNA catabolic process);GO:0005654(nucleoplasm);GO:0090503(RNA phosphodiester bond hydrolysis, exonucleolytic);GO:0000176(nuclear exosome (RNase complex));GO:0070034(telomerase RNA binding);GO:0071044(histone mRNA catabolic process);GO:0000184(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay);GO:1904872(regulation of telomerase RNA localization to Cajal body);GO:0035327(transcriptionally active chromatin);GO:0071028(nuclear mRNA surveillance);GO:0032211(negative regulation of telomere maintenance via telomerase);GO:0000178(exosome (RNase complex));GO:0000460(maturation of 5.8S rRNA);GO:0000175(3'-5'-exoribonuclease activity);GO:0004532(exoribonuclease activity);GO:0071034(CUT catabolic process);GO:0071035(nuclear polyadenylation-dependent rRNA catabolic process);GO:0071048(nuclear retention of unspliced pre-mRNA at the site of transcription);GO:0009048(dosage compensation by inactivation of X chromosome)","03018(RNA degradation)","NA","NA","exosome component 10 [Source:HGNC Symbol;Acc:HGNC:9138]",{"v":0.270401,"d":"0.27"},{"v":0.089742,"d":"0.09"},{"v":3.01309308907758,"d":"3.01"},{"v":1.59124524547668,"d":"1.59"},1,1,"up","no"]
[172769,0,"chr7","+",29479712,29514328,"ENST00000412711",7,2991,"MSTRG.13553","CHN2","GO:0016020(membrane);GO:0046872(metal ion binding);GO:0035556(intracellular signal transduction);GO:0007165(signal transduction);GO:0009967(positive regulation of signal transduction);GO:0043547(positive regulation of GTPase activity);GO:0005515(protein binding);GO:0005096(GTPase activator activity);GO:0051056(regulation of small GTPase mediated signal transduction);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0043087(regulation of GTPase activity);GO:0005070(SH3/SH2 adaptor activity);GO:0005622(intracellular)","NA","NA","NA","chimerin 2 [Source:HGNC Symbol;Acc:HGNC:1944]",{"v":0.055475,"d":"0.06"},{"v":0.037711,"d":"0.04"},{"v":1.47105619050144,"d":"1.47"},{"v":0.556852354824905,"d":"0.56"},1,1,"up","no"]
[18742,0,"chr10","-",14907879,14954095,"ENST00000378246",13,2637,"ENSG00000152457","DCLRE1C","GO:0005634(nucleus);GO:0005794(Golgi apparatus);GO:0005654(nucleoplasm);GO:0016787(hydrolase activity);GO:0090305(nucleic acid phosphodiester bond hydrolysis);GO:0005515(protein binding);GO:0006281(DNA repair);GO:0006310(DNA recombination);GO:0006974(cellular response to DNA damage stimulus);GO:0004519(endonuclease activity);GO:0004527(exonuclease activity);GO:0004518(nuclease activity);GO:0002376(immune system process);GO:0002250(adaptive immune response);GO:0036297(interstrand cross-link repair);GO:0003684(damaged DNA binding);GO:0006303(double-strand break repair via nonhomologous end joining);GO:0070419(nonhomologous end joining complex);GO:0031848(protection from non-homologous end joining at telomere);GO:0000784(nuclear chromosome, telomeric region);GO:0000014(single-stranded DNA endodeoxyribonuclease activity);GO:0008409(5'-3' exonuclease activity);GO:0035312(5'-3' exodeoxyribonuclease activity);GO:0000723(telomere maintenance);GO:0006302(double-strand break repair);GO:0010212(response to ionizing radiation);GO:0030183(B cell differentiation);GO:0033151(V(D)J recombination);GO:0051276(chromosome organization)","03450(Non-homologous end-joining);05340(Primary immunodeficiency)","K10887","EC:3.1.-.-","DNA cross-link repair 1C [Source:HGNC Symbol;Acc:HGNC:17642]",{"v":0.277923,"d":"0.28"},{"v":0.174528,"d":"0.17"},{"v":1.59242643014301,"d":"1.59"},{"v":0.671226721731438,"d":"0.67"},1,1,"up","no"]
[62696,0,"chr15","+",52577842,52598709,"ENST00000562062",4,612,"ENSG00000260618","AC025917.1","NA","NA","NA","NA","NA",{"v":0.050836,"d":"0.05"},0,"inf","inf",1,1,"up","no"]
[41268,0,"chr12","+",49367384,49484673,"ENST00000549298",4,643,"ENSG00000123352","SPATS2","GO:0003723(RNA binding);GO:0005737(cytoplasm);GO:0005829(cytosol)","NA","NA","NA","spermatogenesis associated serine rich 2 [Source:HGNC Symbol;Acc:HGNC:18650]",0,0,1,0,1,1,"no","no"]
[160105,0,"chr5","-",150731375,150758690,"ENST00000519313",6,647,"MSTRG.12463","DCTN4","GO:0005737(cytoplasm);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0005813(centrosome);GO:0005815(microtubule organizing center);GO:0005869(dynactin complex);GO:0005829(cytosol);GO:0019886(antigen processing and presentation of exogenous peptide antigen via MHC class II);GO:0005634(nucleus);GO:0047485(protein N-terminus binding);GO:0006888(ER to Golgi vesicle-mediated transport);GO:0005868(cytoplasmic dynein complex);GO:0007097(nuclear migration)","04962(Vasopressin-regulated water reabsorption);05016(Huntington's disease)","NA","NA","dynactin subunit 4 [Source:HGNC Symbol;Acc:HGNC:15518]",{"v":0.000168,"d":"0.00"},{"v":0.14667,"d":"0.15"},{"v":0.00114542851298834,"d":"0.00"},{"v":-9.7698968628379,"d":"-9.77"},1,1,"down","no"]
[178604,0,"chr7","+",128937989,128950035,"ENST00000402030",9,2786,"ENSG00000128604","IRF5","GO:0043065(positive regulation of apoptotic process);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0005737(cytoplasm);GO:0005634(nucleus);GO:0006355(regulation of transcription, DNA-templated);GO:0006366(transcription from RNA polymerase II promoter);GO:0006351(transcription, DNA-templated);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0005515(protein binding);GO:0051607(defense response to virus);GO:0002376(immune system process);GO:0045087(innate immune response);GO:0000975(regulatory region DNA binding);GO:0019221(cytokine-mediated signaling pathway);GO:0005829(cytosol);GO:0001228(transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding);GO:0043565(sequence-specific DNA binding);GO:0032727(positive regulation of interferon-alpha production);GO:0032728(positive regulation of interferon-beta production);GO:0032735(positive regulation of interleukin-12 production);GO:0060333(interferon-gamma-mediated signaling pathway);GO:0060337(type I interferon signaling pathway);GO:0032494(response to peptidoglycan);GO:0032495(response to muramyl dipeptide)","04620(Toll-like receptor signaling pathway)","K09446","NA","interferon regulatory factor 5 [Source:HGNC Symbol;Acc:HGNC:6120]",0,{"v":0.928643,"d":"0.93"},"-inf","-inf",1,1,"down","no"]
[143140,0,"chr3","+",181711924,181714436,"ENST00000325404",1,2513,"ENSG00000181449","SOX2","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005654(nucleoplasm);GO:0006355(regulation of transcription, DNA-templated);GO:0006366(transcription from RNA polymerase II promoter);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0005829(cytosol);GO:0005515(protein binding);GO:0007275(multicellular organism development);GO:0045893(positive regulation of transcription, DNA-templated);GO:0006325(chromatin organization);GO:0000976(transcription regulatory region sequence-specific DNA binding);GO:0001077(transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0021984(adenohypophysis development);GO:0022409(positive regulation of cell-cell adhesion);GO:0042246(tissue regeneration);GO:0045597(positive regulation of cell differentiation);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0001654(eye development);GO:0090090(negative regulation of canonical Wnt signaling pathway);GO:0007050(cell cycle arrest);GO:0005667(transcription factor complex);GO:0044212(transcription regulatory region DNA binding);GO:0045665(negative regulation of neuron differentiation);GO:0097150(neuronal stem cell population maintenance);GO:0050680(negative regulation of epithelial cell proliferation);GO:0035019(somatic stem cell population maintenance);GO:0043410(positive regulation of MAPK cascade);GO:0001649(osteoblast differentiation);GO:0009611(response to wounding);GO:0021983(pituitary gland development);GO:0048839(inner ear development);GO:0043565(sequence-specific DNA binding);GO:0010468(regulation of gene expression);GO:0070848(response to growth factor);GO:0035198(miRNA binding);GO:0030900(forebrain development);GO:0001714(endodermal cell fate specification);GO:0021781(glial cell fate commitment);GO:0043281(regulation of cysteine-type endopeptidase activity involved in apoptotic process)","04390(Hippo signaling pathway);04550(Signaling pathways regulating pluripotency of stem cells)","K16796","NA","SRY-box 2 [Source:HGNC Symbol;Acc:HGNC:11195]",{"v":0.019432,"d":"0.02"},{"v":0.01404,"d":"0.01"},{"v":1.38404558404558,"d":"1.38"},{"v":0.468891459443942,"d":"0.47"},1,1,"up","no"]
[45235,0,"chr12","+",93848660,93850756,"ENST00000548330",2,1470,"ENSG00000169372","CRADD","GO:0042981(regulation of apoptotic process);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0007165(signal transduction);GO:0005515(protein binding);GO:0006915(apoptotic process);GO:0005829(cytosol);GO:0043065(positive regulation of apoptotic process);GO:0071260(cellular response to mechanical stimulus);GO:0030674(protein binding, bridging);GO:0002020(protease binding);GO:0008625(extrinsic apoptotic signaling pathway via death domain receptors);GO:0006977(DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest);GO:0070513(death domain binding);GO:0006919(activation of cysteine-type endopeptidase activity involved in apoptotic process);GO:2001235(positive regulation of apoptotic signaling pathway)","NA","NA","NA","CASP2 and RIPK1 domain containing adaptor with death domain [Source:HGNC Symbol;Acc:HGNC:2340]",0,{"v":0.006184,"d":"0.01"},"-inf","-inf",1,1,"down","no"]
[81624,0,"chr17","+",30068632,30069631,"ENST00000583091",1,1000,"MSTRG.6639","AC104996.2","NA","NA","NA","NA","NA",{"v":0.051402,"d":"0.05"},{"v":0.042734,"d":"0.04"},{"v":1.20283614920204,"d":"1.20"},{"v":0.266440131430634,"d":"0.27"},1,1,"up","no"]
[51005,0,"chr13","-",76999137,77018686,"ENST00000477982",3,3172,"MSTRG.4034","FBXL3","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016567(protein ubiquitination);GO:0005829(cytosol);GO:0016604(nuclear body);GO:0048511(rhythmic process);GO:0005515(protein binding);GO:0031648(protein destabilization);GO:0000209(protein polyubiquitination);GO:0043687(post-translational protein modification);GO:0004842(ubiquitin-protein transferase activity);GO:0000151(ubiquitin ligase complex);GO:0042752(regulation of circadian rhythm);GO:0043153(entrainment of circadian clock by photoperiod);GO:0019005(SCF ubiquitin ligase complex);GO:0031146(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process);GO:0043161(proteasome-mediated ubiquitin-dependent protein catabolic process)","04710(Circadian rhythm)","NA","NA","F-box and leucine rich repeat protein 3 [Source:HGNC Symbol;Acc:HGNC:13599]",0,0,1,0,1,1,"no","no"]
[161755,0,"chr5","+",178130996,178148568,"ENST00000313386",11,1929,"MSTRG.12586","RMND5B","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0004842(ubiquitin-protein transferase activity);GO:0043161(proteasome-mediated ubiquitin-dependent protein catabolic process);GO:0042787(protein ubiquitination involved in ubiquitin-dependent protein catabolic process);GO:0034657(GID complex)","NA","NA","NA","required for meiotic nuclear division 5 homolog B [Source:HGNC Symbol;Acc:HGNC:26181]",{"v":0.781229,"d":"0.78"},{"v":0.04598,"d":"0.05"},{"v":16.9906263592866,"d":"16.99"},{"v":4.08666713332945,"d":"4.09"},1,1,"up","no"]
[148016,0,"chr4","+",70518540,70532742,"ENST00000339336",9,1037,"ENSG00000187689","AMTN","GO:0007155(cell adhesion);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0042475(odontogenesis of dentin-containing tooth);GO:0031214(biomineral tissue development);GO:0044267(cellular protein metabolic process);GO:0043687(post-translational protein modification);GO:0070175(positive regulation of enamel mineralization);GO:0005578(proteinaceous extracellular matrix);GO:0005605(basal lamina);GO:0005911(cell-cell junction);GO:0005788(endoplasmic reticulum lumen);GO:0003674(molecular_function);GO:0070169(positive regulation of biomineral tissue development)","NA","NA","NA","amelotin [Source:HGNC Symbol;Acc:HGNC:33188]",{"v":0.073089,"d":"0.07"},{"v":0.014189,"d":"0.01"},{"v":5.15110296708718,"d":"5.15"},{"v":2.36488137885393,"d":"2.36"},1,1,"up","no"]
[142266,0,"chr3","+",160411758,160414517,"ENST00000465563",4,747,"ENSG00000113810","SMC4","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016607(nuclear speck);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0005829(cytosol);GO:0051301(cell division);GO:0005694(chromosome);GO:0005515(protein binding);GO:0051276(chromosome organization);GO:0007049(cell cycle);GO:0005654(nucleoplasm);GO:0030261(chromosome condensation);GO:0046982(protein heterodimerization activity);GO:0000070(mitotic sister chromatid segregation);GO:0007076(mitotic chromosome condensation);GO:0000796(condensin complex);GO:0010032(meiotic chromosome condensation);GO:0045132(meiotic chromosome segregation);GO:0051383(kinetochore organization)","NA","NA","NA","structural maintenance of chromosomes 4 [Source:HGNC Symbol;Acc:HGNC:14013]",0,0,1,0,1,1,"no","no"]
[65791,0,"chr15","-",83029543,83041821,"ENST00000560015",3,608,"MSTRG.5375","BTBD1","GO:0005737(cytoplasm);GO:0016567(protein ubiquitination);GO:0000932(P-body);GO:0031625(ubiquitin protein ligase binding);GO:0043161(proteasome-mediated ubiquitin-dependent protein catabolic process);GO:0005515(protein binding);GO:0005829(cytosol);GO:0043687(post-translational protein modification);GO:0030162(regulation of proteolysis);GO:0042787(protein ubiquitination involved in ubiquitin-dependent protein catabolic process);GO:0019005(SCF ubiquitin ligase complex);GO:0043234(protein complex);GO:0022008(neurogenesis);GO:0043393(regulation of protein binding)","NA","NA","NA","BTB domain containing 1 [Source:HGNC Symbol;Acc:HGNC:1120]",{"v":0.073079,"d":"0.07"},0,"inf","inf",1,1,"up","no"]
[98437,0,"chr19","-",17816513,17821505,"ENST00000598577",2,758,"ENSG00000248099","INSL3","GO:0005576(extracellular region);GO:0005179(hormone activity);GO:0007267(cell-cell signaling);GO:0002020(protease binding);GO:0005102(receptor binding);GO:0007283(spermatogenesis);GO:0010634(positive regulation of epithelial cell migration);GO:0005158(insulin receptor binding);GO:0090303(positive regulation of wound healing)","04926(Relaxin signaling pathway)","NA","NA","insulin like 3 [Source:HGNC Symbol;Acc:HGNC:6086]",{"v":1.549085,"d":"1.55"},0,"inf","inf",1,1,"up","no"]
[163967,0,"chr6","-",30102897,30113106,"ENST00000376734",9,2043,"ENSG00000204616","TRIM31","GO:0005737(cytoplasm);GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0016740(transferase activity);GO:0016567(protein ubiquitination);GO:0005622(intracellular);GO:0005739(mitochondrion);GO:0005515(protein binding);GO:0045087(innate immune response);GO:0005829(cytosol);GO:0046597(negative regulation of viral entry into host cell);GO:0051091(positive regulation of sequence-specific DNA binding transcription factor activity);GO:0060333(interferon-gamma-mediated signaling pathway);GO:0032897(negative regulation of viral transcription);GO:1902186(regulation of viral release from host cell)","NA","NA","NA","tripartite motif containing 31 [Source:HGNC Symbol;Acc:HGNC:16289]",0,{"v":0.06439,"d":"0.06"},"-inf","-inf",1,1,"down","no"]
[55801,0,"chr14","+",64119430,64122522,"ENST00000553455",4,674,"ENSG00000054654","SYNE2","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0031965(nuclear membrane);GO:0051015(actin filament binding);GO:0003779(actin binding);GO:0005739(mitochondrion);GO:0045111(intermediate filament cytoskeleton);GO:0005886(plasma membrane);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0016235(aggresome);GO:0034993(LINC complex);GO:0030054(cell junction);GO:0005654(nucleoplasm);GO:0005925(focal adhesion);GO:0090286(cytoskeletal anchoring at nuclear membrane);GO:0005635(nuclear envelope);GO:0070062(extracellular exosome);GO:0016529(sarcoplasmic reticulum);GO:0030335(positive regulation of cell migration);GO:0033017(sarcoplasmic reticulum membrane);GO:0030018(Z disc);GO:0031527(filopodium membrane);GO:0031258(lamellipodium membrane);GO:0051642(centrosome localization);GO:0005640(nuclear outer membrane);GO:0031981(nuclear lumen);GO:0007097(nuclear migration);GO:0031022(nuclear migration along microfilament);GO:0006998(nuclear envelope organization);GO:0007163(establishment or maintenance of cell polarity);GO:0010761(fibroblast migration);GO:0021817(nucleokinesis involved in cell motility in cerebral cortex radial glia guided migration);GO:0034504(protein localization to nucleus);GO:1902017(regulation of cilium assembly);GO:0030016(myofibril)","NA","NA","NA","spectrin repeat containing nuclear envelope protein 2 [Source:HGNC Symbol;Acc:HGNC:17084]",0,{"v":0.173941,"d":"0.17"},"-inf","-inf",1,1,"down","no"]
[166309,0,"chr6","-",43671510,43687791,"ENST00000372116",5,785,"MSTRG.13064","MRPS18A","GO:0006412(translation);GO:0030529(intracellular ribonucleoprotein complex);GO:0005622(intracellular);GO:0003735(structural constituent of ribosome);GO:0005840(ribosome);GO:0005739(mitochondrion);GO:0032543(mitochondrial translation);GO:0005743(mitochondrial inner membrane);GO:0070125(mitochondrial translational elongation);GO:0070126(mitochondrial translational termination);GO:0005763(mitochondrial small ribosomal subunit);GO:0022627(cytosolic small ribosomal subunit)","03010(Ribosome)","K02963","NA","mitochondrial ribosomal protein S18A [Source:HGNC Symbol;Acc:HGNC:14515]",{"v":0.608791,"d":"0.61"},{"v":0.258851,"d":"0.26"},{"v":2.35189742361436,"d":"2.35"},{"v":1.23382513939622,"d":"1.23"},1,1,"up","no"]
[25271,0,"chr11","+",1869642,1886866,"ENST00000457279",8,887,"MSTRG.2106","LSP1","GO:0016020(membrane);GO:0007165(signal transduction);GO:0004871(signal transducer activity);GO:0005886(plasma membrane);GO:0070062(extracellular exosome);GO:0006928(movement of cell or subcellular component);GO:0015629(actin cytoskeleton);GO:0003779(actin binding);GO:0006968(cellular defense response);GO:0006935(chemotaxis);GO:0006952(defense response)","05152(Tuberculosis)","NA","NA","lymphocyte-specific protein 1 [Source:HGNC Symbol;Acc:HGNC:6707]",{"v":6e-05,"d":"0.00"},0,"inf","inf",1,1,"up","no"]
[29421,0,"chr11","+",57761797,57819178,"ENST00000531014",15,5053,"MSTRG.2414","CTNND1","GO:0090090(negative regulation of canonical Wnt signaling pathway);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0007155(cell adhesion);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0016055(Wnt signaling pathway);GO:0016337(single organismal cell-cell adhesion);GO:0045296(cadherin binding);GO:0030496(midbody);GO:0070062(extracellular exosome);GO:0005102(receptor binding);GO:0005829(cytosol);GO:0005911(cell-cell junction);GO:0034332(adherens junction organization);GO:0035635(entry of bacterium into host cell);GO:0019901(protein kinase binding);GO:0050839(cell adhesion molecule binding);GO:0007420(brain development);GO:0005915(zonula adherens);GO:0030027(lamellipodium);GO:0030426(growth cone);GO:0043197(dendritic spine);GO:0045202(synapse)","04015(Rap1 signaling pathway);04520(Adherens junction);04670(Leukocyte transendothelial migration)","NA","NA","catenin delta 1 [Source:HGNC Symbol;Acc:HGNC:2515]",{"v":0.05557,"d":"0.06"},0,"inf","inf",1,1,"up","no"]
[176006,0,"chr7","-",92144842,92179133,"ENST00000458448",6,2830,"ENSG00000240720","LRRD1","GO:0007165(signal transduction);GO:0005737(cytoplasm);GO:0045199(maintenance of epithelial cell apical/basal polarity);GO:0016323(basolateral plasma membrane)","NA","NA","NA","leucine rich repeats and death domain containing 1 [Source:HGNC Symbol;Acc:HGNC:34300]",{"v":0.036145,"d":"0.04"},{"v":0.0299,"d":"0.03"},{"v":1.20886287625418,"d":"1.21"},{"v":0.273650606069537,"d":"0.27"},1,1,"up","no"]
[191994,0,"chr9","-",95870284,95875976,"ENST00000321517",3,1269,"ENSG00000175611","LINC00476","NA","NA","NA","NA","long intergenic non-protein coding RNA 476 [Source:HGNC Symbol;Acc:HGNC:27858]",{"v":0.084852,"d":"0.08"},{"v":0.03829,"d":"0.04"},{"v":2.21603551841212,"d":"2.22"},{"v":1.14798100495496,"d":"1.15"},1,1,"up","no"]
[41218,0,"chr12","+",49196784,49197062,"ENST00000616942",1,279,"MSTRG.3351","Metazoa_SRP","NA","NA","NA","NA","Metazoan signal recognition particle RNA [Source:RFAM;Acc:RF00017]",{"v":0.368473,"d":"0.37"},0,"inf","inf",1,1,"up","no"]
[11670,0,"chr1","-",155216384,155218248,"ENST00000463838",4,830,"MSTRG.1037","GBAP1","NA","NA","NA","NA","glucosylceramidase beta pseudogene 1 [Source:HGNC Symbol;Acc:HGNC:4178]",0,0,1,0,1,1,"no","no"]
[177073,0,"chr7","+",100885295,100886824,"ENST00000449389",5,448,"MSTRG.13838","SRRT","GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005654(nucleoplasm);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0031047(gene silencing by RNA);GO:0008283(cell proliferation);GO:0043234(protein complex);GO:0042795(snRNA transcription from RNA polymerase II promoter);GO:0097150(neuronal stem cell population maintenance);GO:0000398(mRNA splicing, via spliceosome);GO:0031053(primary miRNA processing);GO:0046685(response to arsenic-containing substance);GO:0050769(positive regulation of neurogenesis)","NA","NA","NA","serrate, RNA effector molecule [Source:HGNC Symbol;Acc:HGNC:24101]",{"v":0.256455,"d":"0.26"},{"v":0.244173,"d":"0.24"},{"v":1.05030040176432,"d":"1.05"},{"v":0.0708020194647118,"d":"0.07"},1,1,"up","no"]
[70317,0,"chr16","+",19555416,19700687,"ENST00000542263",28,3138,"ENSG00000103544","C16orf62","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0015031(protein transport);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0005768(endosome);GO:0005769(early endosome);GO:0043312(neutrophil degranulation);GO:0101003(ficolin-1-rich granule membrane);GO:0006893(Golgi to plasma membrane transport)","NA","NA","NA","chromosome 16 open reading frame 62 [Source:HGNC Symbol;Acc:HGNC:24641]",{"v":0.602767,"d":"0.60"},0,"inf","inf",1,1,"up","no"]
[110186,0,"chr2","-",63121383,63433930,"ENST00000409354",9,2122,"MSTRG.8733","WDPCP","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005886(plasma membrane);GO:0005856(cytoskeleton);GO:0042995(cell projection);GO:0060271(cilium assembly);GO:0005929(cilium);GO:0030030(cell projection organization);GO:0005938(cell cortex);GO:0005930(axoneme);GO:0016324(apical plasma membrane);GO:0032880(regulation of protein localization);GO:0001822(kidney development);GO:0002093(auditory receptor cell morphogenesis);GO:0007224(smoothened signaling pathway);GO:0007399(nervous system development);GO:0010762(regulation of fibroblast migration);GO:0016476(regulation of embryonic cell shape);GO:0032185(septin cytoskeleton organization);GO:0042733(embryonic digit morphogenesis);GO:0043010(camera-type eye development);GO:0044782(cilium organization);GO:0045184(establishment of protein localization);GO:0048568(embryonic organ development);GO:0051893(regulation of focal adhesion assembly);GO:0055123(digestive system development);GO:0060021(palate development);GO:0060541(respiratory system development);GO:0072358(cardiovascular system development);GO:0090521(glomerular visceral epithelial cell migration);GO:1900027(regulation of ruffle assembly);GO:2000114(regulation of establishment of cell polarity);GO:0097541(axonemal basal plate)","NA","NA","NA","WD repeat containing planar cell polarity effector [Source:HGNC Symbol;Acc:HGNC:28027]",0,{"v":0.302265,"d":"0.30"},"-inf","-inf",1,1,"down","no"]
[109447,0,"chr2","+",47046315,47050827,"ENST00000496991",3,703,"MSTRG.8674","TTC7A","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005886(plasma membrane);GO:0090002(establishment of protein localization to plasma membrane);GO:0006879(cellular iron ion homeostasis);GO:0030097(hemopoiesis)","NA","NA","NA","tetratricopeptide repeat domain 7A [Source:HGNC Symbol;Acc:HGNC:19750]",0,0,1,0,1,1,"no","no"]
[115770,0,"chr2","-",162038342,162073596,"ENST00000497461",8,781,"MSTRG.9208","DPP4","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016787(hydrolase activity);GO:0007155(cell adhesion);GO:0005765(lysosomal membrane);GO:0042803(protein homodimerization activity);GO:0005886(plasma membrane);GO:0042995(cell projection);GO:0005515(protein binding);GO:0008233(peptidase activity);GO:0006508(proteolysis);GO:0005576(extracellular region);GO:0004252(serine-type endopeptidase activity);GO:0008236(serine-type peptidase activity);GO:0030054(cell junction);GO:0045121(membrane raft);GO:0005925(focal adhesion);GO:0004177(aminopeptidase activity);GO:0042802(identical protein binding);GO:0046718(viral entry into host cell);GO:0030027(lamellipodium);GO:0070062(extracellular exosome);GO:0001666(response to hypoxia);GO:0005102(receptor binding);GO:0008239(dipeptidyl-peptidase activity);GO:0008284(positive regulation of cell proliferation);GO:0016324(apical plasma membrane);GO:0009986(cell surface);GO:0002020(protease binding);GO:0042110(T cell activation);GO:0050796(regulation of insulin secretion);GO:0030139(endocytic vesicle);GO:0043542(endothelial cell migration);GO:0033632(regulation of cell-cell adhesion mediated by integrin);GO:0031258(lamellipodium membrane);GO:0071438(invadopodium membrane);GO:0031295(T cell costimulation);GO:0001618(virus receptor activity);GO:0001662(behavioral fear response);GO:0010716(negative regulation of extracellular matrix disassembly);GO:0035641(locomotory exploration behavior);GO:0036343(psychomotor behavior);GO:0046581(intercellular canaliculus)","04974(Protein digestion and absorption)","NA","NA","dipeptidyl peptidase 4 [Source:HGNC Symbol;Acc:HGNC:3009]",{"v":0.018757,"d":"0.02"},0,"inf","inf",1,1,"up","no"]
[182739,0,"chr8","+",30442617,30545591,"ENST00000520191",6,1613,"ENSG00000157110","RBPMS","GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0042803(protein homodimerization activity);GO:0005515(protein binding);GO:0003713(transcription coactivator activity);GO:0000932(P-body);GO:0000398(mRNA splicing, via spliceosome);GO:0010494(cytoplasmic stress granule);GO:0006979(response to oxidative stress);GO:0010862(positive regulation of pathway-restricted SMAD protein phosphorylation);GO:0008143(poly(A) binding);GO:0006396(RNA processing);GO:0005685(U1 snRNP);GO:0030619(U1 snRNA binding);GO:0035614(snRNA stem-loop binding);GO:0060391(positive regulation of SMAD protein import into nucleus)","NA","NA","NA","RNA binding protein with multiple splicing [Source:HGNC Symbol;Acc:HGNC:19097]",0,{"v":0.007637,"d":"0.01"},"-inf","-inf",1,1,"down","no"]
[26995,0,"chr11","-",16789268,16790095,"ENST00000533251",2,350,"MSTRG.2280","PLEKHA7","GO:0005634(nucleus);GO:0005829(cytosol);GO:0030054(cell junction);GO:0005737(cytoplasm);GO:0005856(cytoskeleton);GO:0005813(centrosome);GO:0005815(microtubule organizing center);GO:0070062(extracellular exosome);GO:0005912(adherens junction);GO:0070097(delta-catenin binding);GO:0090136(epithelial cell-cell adhesion);GO:0045218(zonula adherens maintenance);GO:0005915(zonula adherens)","NA","NA","NA","pleckstrin homology domain containing A7 [Source:HGNC Symbol;Acc:HGNC:27049]",{"v":0.065599,"d":"0.07"},0,"inf","inf",1,1,"up","no"]
[126866,0,"chr21","+",34375509,34400175,"ENST00000489469",4,780,"ENSG00000205670","SMIM11A","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0003674(molecular_function);GO:0008150(biological_process);GO:0005575(cellular_component)","NA","NA","NA","small integral membrane protein 11A [Source:HGNC Symbol;Acc:HGNC:1293]",{"v":0.214395,"d":"0.21"},{"v":0.139716,"d":"0.14"},{"v":1.53450571158636,"d":"1.53"},{"v":0.617774015672096,"d":"0.62"},1,1,"up","no"]
[123211,0,"chr20","-",35306743,35411969,"ENST00000438533",10,736,"ENSG00000101019","UQCC1","GO:0016020(membrane);GO:0005743(mitochondrial inner membrane);GO:0005739(mitochondrion);GO:0031410(cytoplasmic vesicle);GO:0005515(protein binding);GO:0070131(positive regulation of mitochondrial translation);GO:0034551(mitochondrial respiratory chain complex III assembly)","NA","NA","NA","ubiquinol-cytochrome c reductase complex assembly factor 1 [Source:HGNC Symbol;Acc:HGNC:15891]",0,{"v":0.788906,"d":"0.79"},"-inf","-inf",1,1,"down","no"]
[60375,0,"chr15","+",29070658,29102759,"ENST00000382938",6,1954,"MSTRG.4866","APBA2","GO:0006810(transport);GO:0015031(protein transport);GO:0008021(synaptic vesicle);GO:0007268(chemical synaptic transmission);GO:0001540(amyloid-beta binding);GO:0005515(protein binding);GO:0007399(nervous system development);GO:0001701(in utero embryonic development);GO:0007626(locomotory behavior);GO:0010468(regulation of gene expression);GO:0035264(multicellular organism growth);GO:0005886(plasma membrane)","NA","NA","NA","amyloid beta precursor protein binding family A member 2 [Source:HGNC Symbol;Acc:HGNC:579]",{"v":0.425163,"d":"0.43"},{"v":0.046698,"d":"0.05"},{"v":9.10452267763073,"d":"9.10"},{"v":3.18658338308173,"d":"3.19"},1,1,"up","no"]
[165570,0,"chr6","-",35887825,35921101,"ENST00000513367",5,634,"MSTRG.12984","SRPK1","GO:0003723(RNA binding);GO:0006397(mRNA processing);GO:0008380(RNA splicing);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0005829(cytosol);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0005886(plasma membrane);GO:0005783(endoplasmic reticulum);GO:0005515(protein binding);GO:0000287(magnesium ion binding);GO:0030154(cell differentiation);GO:0007059(chromosome segregation);GO:0043231(intracellular membrane-bounded organelle);GO:0016032(viral process);GO:0045087(innate immune response);GO:0016363(nuclear matrix);GO:0045070(positive regulation of viral genome replication);GO:0035556(intracellular signal transduction);GO:0048024(regulation of mRNA splicing, via spliceosome);GO:0000245(spliceosomal complex assembly);GO:0045071(negative regulation of viral genome replication);GO:0050684(regulation of mRNA processing);GO:0035092(sperm chromatin condensation)","05168(Herpes simplex infection)","NA","NA","SRSF protein kinase 1 [Source:HGNC Symbol;Acc:HGNC:11305]",{"v":0.306805,"d":"0.31"},{"v":0.165915,"d":"0.17"},{"v":1.84916975559775,"d":"1.85"},{"v":0.886877671641731,"d":"0.89"},1,1,"up","no"]
[73418,0,"chr16","+",57025762,57083519,"ENST00000545081",44,5832,"MSTRG.5947","NLRC5","GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0005813(centrosome);GO:0002376(immune system process);GO:0045087(innate immune response);GO:0051607(defense response to virus);GO:0005515(protein binding);GO:0005829(cytosol);GO:0060335(positive regulation of interferon-gamma-mediated signaling pathway);GO:0032088(negative regulation of NF-kappaB transcription factor activity);GO:0032480(negative regulation of type I interferon production);GO:0043549(regulation of kinase activity);GO:0060339(negative regulation of type I interferon-mediated signaling pathway);GO:0000979(RNA polymerase II core promoter sequence-specific DNA binding);GO:0045345(positive regulation of MHC class I biosynthetic process);GO:0060340(positive regulation of type I interferon-mediated signaling pathway)","NA","NA","NA","NLR family CARD domain containing 5 [Source:HGNC Symbol;Acc:HGNC:29933]",{"v":0.030001,"d":"0.03"},0,"inf","inf",1,1,"up","no"]
[168477,0,"chr6","-",111558945,111566500,"ENST00000492671",2,664,"ENSG00000056972","TRAF3IP2","GO:0005622(intracellular);GO:0007165(signal transduction);GO:0005515(protein binding);GO:0005575(cellular_component);GO:0043123(positive regulation of I-kappaB kinase/NF-kappaB signaling);GO:0035556(intracellular signal transduction);GO:0002230(positive regulation of defense response to virus by host);GO:0005102(receptor binding);GO:0001783(B cell apoptotic process);GO:0006959(humoral immune response);GO:0048305(immunoglobulin secretion)","04218(Cellular senescence);04657(IL-17 signaling pathway)","NA","NA","TRAF3 interacting protein 2 [Source:HGNC Symbol;Acc:HGNC:1343]",{"v":0.046153,"d":"0.05"},0,"inf","inf",1,1,"up","no"]
[117517,0,"chr2","-",195451778,195515699,"ENST00000606986",3,503,"ENSG00000271893","AC064834.1","NA","NA","NA","NA","NA",0,0,1,0,1,1,"no","no"]
[68987,0,"chr16","-",4189374,4242075,"ENST00000572111",7,5587,"ENSG00000185739","SRL","GO:0005525(GTP binding);GO:0016529(sarcoplasmic reticulum);GO:0033018(sarcoplasmic reticulum lumen)","NA","NA","NA","sarcalumenin [Source:HGNC Symbol;Acc:HGNC:11295]",{"v":0.026624,"d":"0.03"},{"v":0.024256,"d":"0.02"},{"v":1.0976253298153,"d":"1.10"},{"v":0.13438567997,"d":"0.13"},1,1,"up","no"]
[19440,0,"chr10","-",30844634,30984426,"ENST00000361310",7,3144,"MSTRG.1634","ZNF438","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding)","NA","NA","NA","zinc finger protein 438 [Source:HGNC Symbol;Acc:HGNC:21029]",0,0,1,0,1,1,"no","no"]
[81107,0,"chr17","-",28269203,28272365,"ENST00000584928",3,1441,"ENSG00000266306","AC061975.5","NA","NA","NA","NA","NA",0,{"v":0.031661,"d":"0.03"},"-inf","-inf",1,1,"down","no"]
[193596,0,"chr9","+",127804286,127804857,"ENST00000469310",3,404,"MSTRG.14983","FPGS","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0005743(mitochondrial inner membrane);GO:0009058(biosynthetic process);GO:0005739(mitochondrion);GO:0006730(one-carbon metabolic process);GO:0016874(ligase activity);GO:0005759(mitochondrial matrix);GO:0005829(cytosol);GO:0006139(nucleobase-containing compound metabolic process);GO:0046655(folic acid metabolic process);GO:0006536(glutamate metabolic process);GO:0004326(tetrahydrofolylpolyglutamate synthase activity);GO:0001889(liver development);GO:0006760(folic acid-containing compound metabolic process);GO:0007420(brain development);GO:0009396(folic acid-containing compound biosynthetic process);GO:0031100(animal organ regeneration);GO:0046901(tetrahydrofolylpolyglutamate biosynthetic process)","00790(Folate biosynthesis);01523(Antifolate resistance)","NA","NA","folylpolyglutamate synthase [Source:HGNC Symbol;Acc:HGNC:3824]",{"v":0.204272,"d":"0.20"},0,"inf","inf",1,1,"up","no"]
[173939,0,"chr7","+",48035520,48061297,"ENST00000348904",9,2125,"ENSG00000164746","C7orf57","NA","NA","NA","NA","chromosome 7 open reading frame 57 [Source:HGNC Symbol;Acc:HGNC:22247]",{"v":0.023331,"d":"0.02"},{"v":0.061103,"d":"0.06"},{"v":0.381830679344713,"d":"0.38"},{"v":-1.38899506977703,"d":"-1.39"},1,1,"down","no"]
[28641,0,"chr11","+",46936730,47155238,"ENST00000525279",6,560,"MSTRG.2363","C11orf49","GO:0005515(protein binding)","NA","NA","NA","chromosome 11 open reading frame 49 [Source:HGNC Symbol;Acc:HGNC:28720]",{"v":0.171543,"d":"0.17"},0,"inf","inf",1,1,"up","no"]
[31973,0,"chr11","+",67416196,67425605,"ENST00000531388",8,5065,"MSTRG.2610","CARNS1","GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0003824(catalytic activity);GO:0016874(ligase activity);GO:0016887(ATPase activity);GO:0005575(cellular_component);GO:0005829(cytosol);GO:0047730(carnosine synthase activity);GO:0102102(-);GO:0006548(histidine catabolic process);GO:0035499(carnosine biosynthetic process)","00330(Arginine and proline metabolism);00340(Histidine metabolism);00410(beta-Alanine metabolism)","NA","NA","carnosine synthase 1 [Source:HGNC Symbol;Acc:HGNC:29268]",{"v":1.256863,"d":"1.26"},0,"inf","inf",1,1,"up","no"]
[59456,0,"chr14","+",105490296,105492603,"ENST00000443229",5,966,"MSTRG.4737","C14orf80","NA","NA","NA","NA","chromosome 14 open reading frame 80 [Source:HGNC Symbol;Acc:HGNC:20127]",0,0,1,0,1,1,"no","no"]
[25658,0,"chr11","+",3811267,3824357,"ENST00000464590",4,846,"MSTRG.2152","PGAP2","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005794(Golgi apparatus);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005515(protein binding);GO:0000139(Golgi membrane);GO:0006506(GPI anchor biosynthetic process);GO:0008565(protein transporter activity);GO:0015031(protein transport);GO:0006974(cellular response to DNA damage stimulus);GO:0008630(intrinsic apoptotic signaling pathway in response to DNA damage);GO:0042770(signal transduction in response to DNA damage);GO:0042771(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator);GO:1902230(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage);GO:0005634(nucleus)","NA","NA","NA","post-GPI attachment to proteins 2 [Source:HGNC Symbol;Acc:HGNC:17893]",{"v":0.026558,"d":"0.03"},0,"inf","inf",1,1,"up","no"]
[56600,0,"chr14","-",73409976,73463642,"ENST00000553415",4,694,"MSTRG.4515","NUMB","GO:0016020(membrane);GO:0005515(protein binding);GO:0007275(multicellular organism development);GO:0007399(nervous system development);GO:0005925(focal adhesion);GO:0005886(plasma membrane);GO:0045296(cadherin binding);GO:0030335(positive regulation of cell migration);GO:0030136(clathrin-coated vesicle);GO:0050769(positive regulation of neurogenesis);GO:1903077(negative regulation of protein localization to plasma membrane);GO:0021670(lateral ventricle development);GO:0021849(neuroblast division in subventricular zone);GO:0008013(beta-catenin binding);GO:0045294(alpha-catenin binding);GO:0007405(neuroblast proliferation);GO:0007409(axonogenesis);GO:0030862(positive regulation of polarized epithelial cell differentiation);GO:0030900(forebrain development);GO:0034332(adherens junction organization);GO:0045746(negative regulation of Notch signaling pathway);GO:0060487(lung epithelial cell differentiation);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005769(early endosome);GO:0016323(basolateral plasma membrane);GO:0019897(extrinsic component of plasma membrane);GO:0031410(cytoplasmic vesicle);GO:0045177(apical part of cell)","04330(Notch signaling pathway)","NA","NA","NUMB, endocytic adaptor protein [Source:HGNC Symbol;Acc:HGNC:8060]",{"v":0.274989,"d":"0.27"},{"v":1.539681,"d":"1.54"},{"v":0.178601281694065,"d":"0.18"},{"v":-2.48518566119734,"d":"-2.49"},1,1,"down","no"]
[77059,0,"chr16","-",89739282,89749816,"ENST00000568626",9,727,"MSTRG.6256","FANCA","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005515(protein binding);GO:0006281(DNA repair);GO:0006974(cellular response to DNA damage stimulus);GO:0043240(Fanconi anaemia nuclear complex);GO:0005654(nucleoplasm);GO:0036297(interstrand cross-link repair);GO:0006461(protein complex assembly);GO:0007140(male meiotic nuclear division);GO:0008584(male gonad development);GO:0008585(female gonad development);GO:0042127(regulation of cell proliferation);GO:0045589(regulation of regulatory T cell differentiation);GO:0050727(regulation of inflammatory response);GO:0051090(regulation of sequence-specific DNA binding transcription factor activity);GO:2000348(regulation of CD40 signaling pathway)","03460(Fanconi anemia pathway)","NA","NA","Fanconi anemia complementation group A [Source:HGNC Symbol;Acc:HGNC:3582]",0,0,1,0,1,1,"no","no"]
[35947,0,"chr11","+",119067692,119081978,"ENST00000621676",16,3313,"MSTRG.2926","VPS11","GO:0006886(intracellular protein transport);GO:0016192(vesicle-mediated transport);GO:1901998(toxin transport);GO:0005769(early endosome);GO:0005884(actin filament);GO:0030123(AP-3 adaptor complex);GO:0033263(CORVET complex);GO:0005622(intracellular);GO:0006810(transport);GO:0016020(membrane);GO:0015031(protein transport);GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0005765(lysosomal membrane);GO:0005515(protein binding);GO:0006914(autophagy);GO:0031410(cytoplasmic vesicle);GO:0005764(lysosome);GO:0005768(endosome);GO:0031902(late endosome membrane);GO:0008333(endosome to lysosome transport);GO:0005770(late endosome);GO:0005776(autophagosome);GO:0007032(endosome organization);GO:0019905(syntaxin binding);GO:0019904(protein domain specific binding);GO:0030136(clathrin-coated vesicle);GO:1903955(positive regulation of protein targeting to mitochondrion);GO:0030139(endocytic vesicle);GO:0031647(regulation of protein stability);GO:1902115(regulation of organelle assembly);GO:1903364(positive regulation of cellular protein catabolic process);GO:2000643(positive regulation of early endosome to late endosome transport);GO:0034058(endosomal vesicle fusion);GO:0035542(regulation of SNARE complex assembly);GO:0030897(HOPS complex);GO:0006904(vesicle docking involved in exocytosis);GO:0030674(protein binding, bridging);GO:0007040(lysosome organization)","NA","NA","NA","VPS11, CORVET/HOPS core subunit [Source:HGNC Symbol;Acc:HGNC:14583]",{"v":0.107426,"d":"0.11"},{"v":1.06793,"d":"1.07"},{"v":0.100592735478917,"d":"0.10"},{"v":-3.31340197331218,"d":"-3.31"},1,1,"down","no"]
[81730,0,"chr17","+",30731706,30758335,"ENST00000497969",6,886,"MSTRG.6605","SUZ12P1","NA","NA","NA","NA","SUZ12 polycomb repressive complex 2 subunit pseudogene 1 [Source:HGNC Symbol;Acc:HGNC:32421]",{"v":0.032889,"d":"0.03"},{"v":1.479645,"d":"1.48"},{"v":0.0222276289245055,"d":"0.02"},{"v":-5.49150212900767,"d":"-5.49"},1,1,"down","no"]
[34831,0,"chr11","-",108158793,108170201,"ENST00000530859",5,1806,"MSTRG.2835","NPAT","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0007049(cell cycle);GO:0003713(transcription coactivator activity);GO:0045893(positive regulation of transcription, DNA-templated);GO:0005654(nucleoplasm);GO:1903507(negative regulation of nucleic acid-templated transcription);GO:0005515(protein binding);GO:0003714(transcription corepressor activity);GO:0008022(protein C-terminus binding);GO:0047485(protein N-terminus binding);GO:0000083(regulation of transcription involved in G1/S transition of mitotic cell cycle);GO:0097504(Gemini of coiled bodies);GO:0015030(Cajal body);GO:0010468(regulation of gene expression)","NA","NA","NA","nuclear protein, coactivator of histone transcription [Source:HGNC Symbol;Acc:HGNC:7896]",0,{"v":0.016198,"d":"0.02"},"-inf","-inf",1,1,"down","no"]
[198053,0,"chrX","-",70925582,70931096,"ENST00000374299",12,2236,"ENSG00000165349","SLC7A3","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005886(plasma membrane);GO:0015171(amino acid transmembrane transporter activity);GO:0003333(amino acid transmembrane transport);GO:1990822(basic amino acid transmembrane transport);GO:0006865(amino acid transport);GO:1903826(arginine transmembrane transport);GO:1903401(L-lysine transmembrane transport);GO:0015174(basic amino acid transmembrane transporter activity);GO:0015181(arginine transmembrane transporter activity);GO:0015189(L-lysine transmembrane transporter activity);GO:0015809(arginine transport);GO:1902475(L-alpha-amino acid transmembrane transport)","NA","NA","NA","solute carrier family 7 member 3 [Source:HGNC Symbol;Acc:HGNC:11061]",{"v":0.0251,"d":"0.03"},{"v":0.058084,"d":"0.06"},{"v":0.432132773224985,"d":"0.43"},{"v":-1.21045344489891,"d":"-1.21"},1,1,"down","no"]
[6688,0,"chr1","-",61683452,61696241,"ENST00000488410",4,476,"ENSG00000162604","TM2D1","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0006915(apoptotic process);GO:0007186(G-protein coupled receptor signaling pathway);GO:0097190(apoptotic signaling pathway);GO:0004930(G-protein coupled receptor activity);GO:0001540(amyloid-beta binding);GO:0005887(integral component of plasma membrane)","NA","NA","NA","TM2 domain containing 1 [Source:HGNC Symbol;Acc:HGNC:24142]",{"v":0.643471,"d":"0.64"},{"v":0.679211,"d":"0.68"},{"v":0.947380121935599,"d":"0.95"},{"v":-0.0779846934829335,"d":"-0.08"},1,1,"down","no"]
[145417,0,"chr4","+",2812301,2827296,"ENST00000511185",5,1071,"MSTRG.11502","SH3BP2","GO:0009967(positive regulation of signal transduction);GO:0005515(protein binding);GO:0017124(SH3 domain binding);GO:0007165(signal transduction);GO:0001784(phosphotyrosine residue binding);GO:0005070(SH3/SH2 adaptor activity)","04650(Natural killer cell mediated cytotoxicity)","NA","NA","SH3 domain binding protein 2 [Source:HGNC Symbol;Acc:HGNC:10825]",{"v":0.272788,"d":"0.27"},{"v":0.146223,"d":"0.15"},{"v":1.86556150537193,"d":"1.87"},{"v":0.899609924899983,"d":"0.90"},1,1,"up","no"]
[186857,0,"chr8","-",123231404,123239386,"ENST00000518996",3,836,"MSTRG.14542","C8orf76","NA","NA","NA","NA","chromosome 8 open reading frame 76 [Source:HGNC Symbol;Acc:HGNC:25924]",{"v":0.108931,"d":"0.11"},0,"inf","inf",1,1,"up","no"]
[73613,0,"chr16","+",57628632,57651554,"ENST00000568234",3,640,"MSTRG.5971","ADGRG1","GO:0005622(intracellular);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0004930(G-protein coupled receptor activity);GO:0007186(G-protein coupled receptor signaling pathway);GO:0007155(cell adhesion);GO:0005886(plasma membrane);GO:0004871(signal transducer activity);GO:0007165(signal transduction);GO:0005576(extracellular region);GO:0004888(transmembrane signaling receptor activity);GO:0007166(cell surface receptor signaling pathway);GO:0007275(multicellular organism development);GO:0007399(nervous system development);GO:0030154(cell differentiation);GO:0045121(membrane raft);GO:0008201(heparin binding);GO:0070062(extracellular exosome);GO:0050840(extracellular matrix binding);GO:0008285(negative regulation of cell proliferation);GO:0005887(integral component of plasma membrane);GO:0007267(cell-cell signaling);GO:0045785(positive regulation of cell adhesion);GO:0016477(cell migration);GO:0001525(angiogenesis);GO:0007266(Rho protein signal transduction);GO:0005518(collagen binding);GO:0070528(protein kinase C signaling);GO:0035025(positive regulation of Rho protein signal transduction);GO:2001223(negative regulation of neuron migration);GO:0021819(layer formation in cerebral cortex);GO:0021801(cerebral cortex radial glia guided migration);GO:0007420(brain development);GO:0010573(vascular endothelial growth factor production);GO:0097451(glial limiting end-foot);GO:0021796(cerebral cortex regionalization);GO:0072520(seminiferous tubule development);GO:2000179(positive regulation of neural precursor cell proliferation)","NA","NA","NA","adhesion G protein-coupled receptor G1 [Source:HGNC Symbol;Acc:HGNC:4512]",{"v":0.067803,"d":"0.07"},0,"inf","inf",1,1,"up","no"]
[179582,0,"chr7","-",142812586,142813399,"ENST00000417977",2,447,"ENSG00000237254","TRBV30","NA","NA","NA","NA","T-cell receptor beta variable 30 (gene/pseudogene) [Source:HGNC Symbol;Acc:HGNC:12214]",{"v":3.487748,"d":"3.49"},0,"inf","inf",1,1,"up","no"]
[110486,0,"chr2","+",68734882,68826302,"ENST00000467265",10,2247,"MSTRG.8782","ARHGAP25","GO:0007165(signal transduction);GO:0043547(positive regulation of GTPase activity);GO:0005096(GTPase activator activity);GO:0005829(cytosol);GO:0051056(regulation of small GTPase mediated signal transduction)","NA","NA","NA","Rho GTPase activating protein 25 [Source:HGNC Symbol;Acc:HGNC:28951]",{"v":0.770431,"d":"0.77"},{"v":0.284026,"d":"0.28"},{"v":2.71253688042644,"d":"2.71"},{"v":1.43964275298444,"d":"1.44"},1,1,"up","no"]
[58050,0,"chr14","+",94110749,94116695,"ENST00000621160",5,644,"MSTRG.4637","IFI27","GO:0016020(membrane);GO:0016021(integral component of membrane)","NA","NA","NA","interferon alpha inducible protein 27 [Source:HGNC Symbol;Acc:HGNC:5397]",0,{"v":0.008336,"d":"0.01"},"-inf","-inf",1,1,"down","no"]
[12179,0,"chr1","-",156668763,156677397,"ENST00000368223",4,5558,"ENSG00000132688","NES","GO:0005198(structural molecule activity);GO:0045111(intermediate filament cytoskeleton);GO:0005882(intermediate filament);GO:0007275(multicellular organism development);GO:0007399(nervous system development);GO:0003674(molecular_function);GO:0031012(extracellular matrix);GO:0019215(intermediate filament binding);GO:2000179(positive regulation of neural precursor cell proliferation);GO:0007420(brain development);GO:0032091(negative regulation of protein binding);GO:0043086(negative regulation of catalytic activity);GO:0007417(central nervous system development);GO:0000086(G2/M transition of mitotic cell cycle);GO:0072089(stem cell proliferation);GO:0005737(cytoplasm);GO:0031076(embryonic camera-type eye development);GO:0030844(positive regulation of intermediate filament depolymerization);GO:0043524(negative regulation of neuron apoptotic process);GO:0048858(cell projection morphogenesis)","NA","NA","NA","nestin [Source:HGNC Symbol;Acc:HGNC:7756]",{"v":0.081971,"d":"0.08"},{"v":0.029719,"d":"0.03"},{"v":2.75820182374912,"d":"2.76"},{"v":1.46372802591242,"d":"1.46"},1,1,"up","no"]
[146829,0,"chr4","+",39459058,39477414,"ENST00000640381",11,2259,"MSTRG.11580","LIAS","GO:0046872(metal ion binding);GO:0016740(transferase activity);GO:0003824(catalytic activity);GO:0005739(mitochondrion);GO:0051536(iron-sulfur cluster binding);GO:0051539(4 iron, 4 sulfur cluster binding);GO:0016783(sulfurtransferase activity);GO:0016992(lipoate synthase activity);GO:0001843(neural tube closure);GO:0006954(inflammatory response);GO:0006979(response to oxidative stress);GO:0009107(lipoate biosynthetic process);GO:0009249(protein lipoylation);GO:0032496(response to lipopolysaccharide);GO:0005759(mitochondrial matrix);GO:0034641(cellular nitrogen compound metabolic process)","00785(Lipoic acid metabolism)","K03644","EC:2.8.1.8","lipoic acid synthetase [Source:HGNC Symbol;Acc:HGNC:16429]",{"v":0.016479,"d":"0.02"},{"v":0.020346,"d":"0.02"},{"v":0.809938071365379,"d":"0.81"},{"v":-0.304116492506938,"d":"-0.30"},1,1,"down","no"]
[33890,0,"chr11","+",86277098,86278739,"ENST00000528250",2,1235,"ENSG00000074266","EED","GO:0005634(nucleus);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0016569(covalent chromatin modification);GO:0005694(chromosome);GO:0005515(protein binding);GO:0042802(identical protein binding);GO:0035098(ESC/E(Z) complex);GO:0045892(negative regulation of transcription, DNA-templated);GO:0045814(negative regulation of gene expression, epigenetic);GO:0042054(histone methyltransferase activity);GO:0046976(histone methyltransferase activity (H3-K27 specific));GO:0070734(histone H3-K27 methylation);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:0003682(chromatin binding);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0006349(regulation of gene expression by genetic imprinting);GO:0016571(histone methylation);GO:0021510(spinal cord development);GO:0061087(positive regulation of histone H3-K27 methylation);GO:1990830(cellular response to leukemia inhibitory factor);GO:2000011(regulation of adaxial/abaxial pattern formation);GO:0001739(sex chromatin);GO:0045120(pronucleus)","NA","NA","NA","embryonic ectoderm development [Source:HGNC Symbol;Acc:HGNC:3188]",{"v":0.046571,"d":"0.05"},{"v":0.051057,"d":"0.05"},{"v":0.912137415045929,"d":"0.91"},{"v":-0.132676909673489,"d":"-0.13"},1,1,"down","no"]
[48769,0,"chr12","+",133037292,133063298,"ENST00000392319",5,7020,"ENSG00000198040","ZNF84","GO:0003676(nucleic acid binding);GO:0046872(metal ion binding);GO:0006355(regulation of transcription, DNA-templated);GO:0005622(intracellular);GO:0005634(nucleus);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0008270(zinc ion binding);GO:0001570(vasculogenesis);GO:0001822(kidney development);GO:0006807(nitrogen compound metabolic process);GO:0009791(post-embryonic development);GO:0014909(smooth muscle cell migration);GO:0030097(hemopoiesis);GO:0035264(multicellular organism growth);GO:0048008(platelet-derived growth factor receptor signaling pathway);GO:0048705(skeletal system morphogenesis);GO:0048745(smooth muscle tissue development);GO:0060021(palate development);GO:0060325(face morphogenesis)","NA","NA","NA","zinc finger protein 84 [Source:HGNC Symbol;Acc:HGNC:13159]",0,0,1,0,1,1,"no","no"]
[118059,0,"chr2","+",201475671,201478567,"ENST00000468123",3,725,"MSTRG.9359","STRADB","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0004672(protein kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0000166(nucleotide binding);GO:0005829(cytosol);GO:0005515(protein binding);GO:0016235(aggresome);GO:0007049(cell cycle);GO:0000902(cell morphogenesis);GO:0007254(JNK cascade);GO:2001240(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand);GO:0042981(regulation of apoptotic process);GO:0007346(regulation of mitotic cell cycle);GO:0007050(cell cycle arrest);GO:0032147(activation of protein kinase activity);GO:0031098(stress-activated protein kinase signaling cascade);GO:0006611(protein export from nucleus)","04152(AMPK signaling pathway);04150(mTOR signaling pathway)","NA","NA","STE20-related kinase adaptor beta [Source:HGNC Symbol;Acc:HGNC:13205]",{"v":0.291883,"d":"0.29"},{"v":0.21602,"d":"0.22"},{"v":1.35118507545598,"d":"1.35"},{"v":0.434225298020613,"d":"0.43"},1,1,"up","no"]
[67595,0,"chr16","-",682543,684155,"ENST00000563088",7,1067,"MSTRG.5487","JMJD8","GO:0070062(extracellular exosome)","NA","NA","NA","jumonji domain containing 8 [Source:HGNC Symbol;Acc:HGNC:14148]",{"v":2.017075,"d":"2.02"},{"v":0.040844,"d":"0.04"},{"v":49.3848545686025,"d":"49.38"},{"v":5.62599675635397,"d":"5.63"},1,1,"up","no"]
[87834,0,"chr17","+",75074306,75079549,"ENST00000455685",4,2848,"ENSG00000232724","TRIM80P","NA","NA","NA","NA","tripartite motif containing 80, pseudogene [Source:HGNC Symbol;Acc:HGNC:51490]",0,0,1,0,1,1,"no","no"]
[135808,0,"chr3","-",48294655,48301367,"ENST00000435684",5,599,"ENSG00000172113","NME6","GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0004550(nucleoside diphosphate kinase activity);GO:0006165(nucleoside diphosphate phosphorylation);GO:0006183(GTP biosynthetic process);GO:0006228(UTP biosynthetic process);GO:0006241(CTP biosynthetic process);GO:0005739(mitochondrion);GO:0046872(metal ion binding);GO:0006915(apoptotic process);GO:0009117(nucleotide metabolic process);GO:0005829(cytosol);GO:0030308(negative regulation of cell growth);GO:0015949(nucleobase-containing small molecule interconversion);GO:0045839(negative regulation of mitotic nuclear division)","00230(Purine metabolism);00240(Pyrimidine metabolism);00983(Drug metabolism - other enzymes)","K00940","EC:2.7.4.6","NME/NM23 nucleoside diphosphate kinase 6 [Source:HGNC Symbol;Acc:HGNC:20567]",0,{"v":0.760091,"d":"0.76"},"-inf","-inf",1,1,"down","no"]
[34373,0,"chr11","+",95482406,95497553,"ENST00000511947",3,570,"ENSG00000250390","AP001790.1","NA","NA","NA","NA","NA",0,{"v":0.080042,"d":"0.08"},"-inf","-inf",1,1,"down","no"]
[47224,0,"chr12","-",118150909,118152753,"ENST00000536979",2,777,"MSTRG.3774","TAOK3","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0006281(DNA repair);GO:0006974(cellular response to DNA damage stimulus);GO:0000186(activation of MAPKK activity);GO:0007399(nervous system development);GO:0006469(negative regulation of protein kinase activity);GO:0042981(regulation of apoptotic process);GO:0007095(mitotic G2 DNA damage checkpoint);GO:0032874(positive regulation of stress-activated MAPK cascade);GO:0004860(protein kinase inhibitor activity);GO:0043507(positive regulation of JUN kinase activity);GO:0046777(protein autophosphorylation);GO:0004709(MAP kinase kinase kinase activity);GO:0000165(MAPK cascade);GO:0046329(negative regulation of JNK cascade);GO:0046330(positive regulation of JNK cascade)","04010(MAPK signaling pathway)","NA","NA","TAO kinase 3 [Source:HGNC Symbol;Acc:HGNC:18133]",{"v":0.201312,"d":"0.20"},{"v":0.049714,"d":"0.05"},{"v":4.04940258277346,"d":"4.05"},{"v":2.01770907973917,"d":"2.02"},1,1,"up","no"]
[47097,0,"chr12","-",115970674,115972465,"ENST00000548784",2,485,"MSTRG.3750","MED13L","GO:0005634(nucleus);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0001104(RNA polymerase II transcription cofactor activity);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0016592(mediator complex)","04919(Thyroid hormone signaling pathway)","NA","NA","mediator complex subunit 13 like [Source:HGNC Symbol;Acc:HGNC:22962]",{"v":0.023861,"d":"0.02"},0,"inf","inf",1,1,"up","no"]
[145695,0,"chr4","+",6269850,6303265,"ENST00000226760",8,3640,"ENSG00000109501","WFS1","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005515(protein binding);GO:0055074(calcium ion homeostasis);GO:0030433(ubiquitin-dependent ERAD pathway);GO:0044267(cellular protein metabolic process);GO:0043687(post-translational protein modification);GO:0005788(endoplasmic reticulum lumen);GO:0050821(protein stabilization);GO:0051117(ATPase binding);GO:0036498(IRE1-mediated unfolded protein response);GO:0034976(response to endoplasmic reticulum stress);GO:0031625(ubiquitin protein ligase binding);GO:0051247(positive regulation of protein metabolic process);GO:0007605(sensory perception of sound);GO:0001822(kidney development);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0043524(negative regulation of neuron apoptotic process);GO:0030425(dendrite);GO:0003091(renal water homeostasis);GO:0006983(ER overload response);GO:0007601(visual perception);GO:0022417(protein maturation by protein folding);GO:0031398(positive regulation of protein ubiquitination);GO:0032469(endoplasmic reticulum calcium ion homeostasis);GO:0042593(glucose homeostasis);GO:0043069(negative regulation of programmed cell death);GO:0043433(negative regulation of sequence-specific DNA binding transcription factor activity);GO:0045927(positive regulation of growth);GO:0050877(neurological system process);GO:0051928(positive regulation of calcium ion transport);GO:1903892(negative regulation of ATF6-mediated unfolded protein response);GO:2000675(negative regulation of type B pancreatic cell apoptotic process);GO:0030176(integral component of endoplasmic reticulum membrane);GO:0005516(calmodulin binding);GO:0033613(activating transcription factor binding);GO:0048306(calcium-dependent protein binding);GO:0030968(endoplasmic reticulum unfolded protein response);GO:0031016(pancreas development);GO:0042048(olfactory behavior);GO:0045762(positive regulation of adenylate cyclase activity);GO:1902236(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway);GO:0000502(proteasome complex)","04141(Protein processing in endoplasmic reticulum)","K14020","NA","wolframin ER transmembrane glycoprotein [Source:HGNC Symbol;Acc:HGNC:12762]",0,0,1,0,1,1,"no","no"]
[147668,"j","chr4","+",56977474,57031158,"MSTRG.11643.1",26,4134,"MSTRG.11643","POLR2B","NA","NA","NA","NA","NA",0,0,1,0,1,1,"no","no"]
[8239,0,"chr1","-",94974407,95072945,"ENST00000370205",4,9367,"ENSG00000172339","ALG14","GO:0005634(nucleus);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0006488(dolichol-linked oligosaccharide biosynthetic process);GO:0031965(nuclear membrane);GO:0004577(N-acetylglucosaminyldiphosphodolichol N-acetylglucosaminyltransferase activity)","00510(N-Glycan biosynthesis)","K07441","EC:2.4.1.141","ALG14, UDP-N-acetylglucosaminyltransferase subunit [Source:HGNC Symbol;Acc:HGNC:28287]",{"v":0.096069,"d":"0.10"},{"v":0.056549,"d":"0.06"},{"v":1.69886293303153,"d":"1.70"},{"v":0.764569458282763,"d":"0.76"},1,1,"up","no"]
[152964,0,"chr4","+",190087705,190088979,"ENST00000630187",1,1275,"ENSG00000281627","DUX4L3","NA","NA","NA","NA","double homeobox 4 like 3 [Source:HGNC Symbol;Acc:HGNC:38688]",{"v":0.00288,"d":"0.00"},0,"inf","inf",1,1,"up","no"]
[161619,0,"chr5","-",177502088,177510382,"ENST00000377112",5,1884,"MSTRG.12582","DOK3","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0005158(insulin receptor binding);GO:0043312(neutrophil degranulation);GO:0030667(secretory granule membrane);GO:0101003(ficolin-1-rich granule membrane)","NA","NA","NA","docking protein 3 [Source:HGNC Symbol;Acc:HGNC:24583]",0,{"v":0.211482,"d":"0.21"},"-inf","-inf",1,1,"down","no"]
[189782,0,"chr9","+",34318407,34319655,"ENST00000419794",1,1249,"ENSG00000229207","SERPINH1P1","NA","NA","NA","NA","serpin family H member 1 pseudogene 1 [Source:HGNC Symbol;Acc:HGNC:19917]",0,{"v":0.072935,"d":"0.07"},"-inf","-inf",1,1,"down","no"]
[100406,0,"chr19","-",36010738,36014213,"ENST00000466196",5,556,"ENSG00000239382","ALKBH6","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0005654(nucleoplasm);GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0005925(focal adhesion);GO:0051213(dioxygenase activity);GO:0005515(protein binding);GO:0008198(ferrous iron binding)","NA","NA","NA","alkB homolog 6 [Source:HGNC Symbol;Acc:HGNC:28243]",{"v":0.274217,"d":"0.27"},{"v":1.051965,"d":"1.05"},{"v":0.260671220050097,"d":"0.26"},{"v":-1.93969678697748,"d":"-1.94"},1,1,"down","no"]
[143815,0,"chr3","+",186717331,186743619,"ENST00000265023",10,3435,"MSTRG.11415","KNG1","GO:0010951(negative regulation of endopeptidase activity);GO:0008270(zinc ion binding);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0005615(extracellular space);GO:0006954(inflammatory response);GO:0005886(plasma membrane);GO:0004869(cysteine-type endopeptidase inhibitor activity);GO:0030414(peptidase inhibitor activity);GO:0010466(negative regulation of peptidase activity);GO:0050880(regulation of blood vessel size);GO:0008201(heparin binding);GO:0070062(extracellular exosome);GO:0044267(cellular protein metabolic process);GO:0072562(blood microparticle);GO:0043687(post-translational protein modification);GO:0043065(positive regulation of apoptotic process);GO:0005102(receptor binding);GO:0002576(platelet degranulation);GO:0007596(blood coagulation);GO:0007599(hemostasis);GO:0005788(endoplasmic reticulum lumen);GO:0031093(platelet alpha granule lumen);GO:0007204(positive regulation of cytosolic calcium ion concentration);GO:0007162(negative regulation of cell adhesion);GO:0007597(blood coagulation, intrinsic pathway);GO:0045861(negative regulation of proteolysis);GO:0030195(negative regulation of blood coagulation);GO:0042311(vasodilation)","04610(Complement and coagulation cascades)","K03898","NA","kininogen 1 [Source:HGNC Symbol;Acc:HGNC:6383]",0,{"v":0.017732,"d":"0.02"},"-inf","-inf",1,1,"down","no"]
[9440,0,"chr1","-",113900331,113902119,"ENST00000472122",3,583,"MSTRG.822","AP4B1","GO:0006810(transport);GO:0016020(membrane);GO:0008565(protein transporter activity);GO:0006886(intracellular protein transport);GO:0015031(protein transport);GO:0016192(vesicle-mediated transport);GO:0030117(membrane coat);GO:0030131(clathrin adaptor complex);GO:0005794(Golgi apparatus);GO:0005515(protein binding);GO:0005905(clathrin-coated pit);GO:0005215(transporter activity);GO:0031904(endosome lumen);GO:0032588(trans-Golgi network membrane);GO:0005802(trans-Golgi network)","04142(Lysosome)","NA","NA","adaptor related protein complex 4 beta 1 subunit [Source:HGNC Symbol;Acc:HGNC:572]",{"v":0.189447,"d":"0.19"},{"v":0.38737,"d":"0.39"},{"v":0.489059555463769,"d":"0.49"},{"v":-1.03191793412595,"d":"-1.03"},1,1,"down","no"]
[177357,0,"chr7","-",102883572,102973219,"ENST00000477915",7,743,"MSTRG.13881","FBXL13","GO:0005829(cytosol);GO:0000209(protein polyubiquitination);GO:0043687(post-translational protein modification);GO:0004842(ubiquitin-protein transferase activity)","NA","NA","NA","F-box and leucine rich repeat protein 13 [Source:HGNC Symbol;Acc:HGNC:21658]",{"v":0.020755,"d":"0.02"},{"v":0.617952,"d":"0.62"},{"v":0.0335867510745171,"d":"0.03"},{"v":-4.8959639427399,"d":"-4.90"},1,1,"down","no"]
[99106,0,"chr19","-",20551085,20565809,"ENST00000596797",4,569,"ENSG00000237440","ZNF737","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0005622(intracellular)","NA","NA","NA","zinc finger protein 737 [Source:HGNC Symbol;Acc:HGNC:32468]",{"v":0.906799,"d":"0.91"},0,"inf","inf",1,1,"up","no"]
[14722,0,"chr1","-",201135801,201154418,"ENST00000435310",6,507,"ENSG00000116857","TMEM9","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005765(lysosomal membrane);GO:0005764(lysosome);GO:0005768(endosome);GO:0031902(late endosome membrane);GO:0003674(molecular_function);GO:0008150(biological_process);GO:0005770(late endosome)","NA","NA","NA","transmembrane protein 9 [Source:HGNC Symbol;Acc:HGNC:18823]",0,0,1,0,1,1,"no","no"]
[40321,0,"chr12","-",34191279,34218853,"ENST00000545923",4,501,"ENSG00000255652","AC140847.2","NA","NA","NA","NA","NA",0,0,1,0,1,1,"no","no"]
[79112,0,"chr17","+",7935676,7936796,"ENST00000576587",2,903,"MSTRG.6411","CNTROB","GO:0005829(cytosol);GO:0005813(centrosome);GO:0005737(cytoplasm);GO:0051301(cell division);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0007049(cell cycle);GO:0005814(centriole);GO:0019904(protein domain specific binding);GO:0007099(centriole replication);GO:0051299(centrosome separation);GO:1902410(mitotic cytokinetic process)","NA","NA","NA","centrobin, centriole duplication and spindle assembly protein [Source:HGNC Symbol;Acc:HGNC:29616]",{"v":0.122915,"d":"0.12"},0,"inf","inf",1,1,"up","no"]
[196998,0,"chrX","+",48689020,48689594,"ENST00000470107",2,322,"MSTRG.15275","WAS","GO:0003779(actin binding);GO:0007015(actin filament organization);GO:2000601(positive regulation of Arp2/3 complex-mediated actin nucleation);GO:0005622(intracellular);GO:0005737(cytoplasm);GO:0042802(identical protein binding);GO:0008154(actin polymerization or depolymerization);GO:0016197(endosomal transport);GO:0030041(actin filament polymerization);GO:0030048(actin filament-based movement);GO:0042110(T cell activation);GO:0005911(cell-cell junction);GO:0012506(vesicle membrane);GO:0050790(regulation of catalytic activity);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0038096(Fc-gamma receptor signaling pathway involved in phagocytosis);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0050852(T cell receptor signaling pathway);GO:0017124(SH3 domain binding);GO:0007596(blood coagulation);GO:0030695(GTPase regulator activity);GO:0006461(protein complex assembly);GO:0015629(actin cytoskeleton);GO:0006952(defense response);GO:0019901(protein kinase binding);GO:0008544(epidermis development);GO:0043274(phospholipase binding);GO:0006955(immune response);GO:0051497(negative regulation of stress fiber assembly);GO:0031267(small GTPase binding);GO:0048365(Rac GTPase binding);GO:0002625(regulation of T cell antigen processing and presentation);GO:0008064(regulation of actin polymerization or depolymerization);GO:0010591(regulation of lamellipodium assembly);GO:0032488(Cdc42 protein signal transduction);GO:0051492(regulation of stress fiber assembly);GO:2000146(negative regulation of cell motility);GO:0005884(actin filament)","04144(Endocytosis);04520(Adherens junction);04530(Tight junction);04810(Regulation of actin cytoskeleton);04666(Fc gamma R-mediated phagocytosis);04062(Chemokine signaling pathway);05231(Choline metabolism in cancer);05130(Pathogenic Escherichia coli infection);05132(Salmonella infection);05131(Shigellosis);05100(Bacterial invasion of epithelial cells)","NA","NA","Wiskott-Aldrich syndrome [Source:HGNC Symbol;Acc:HGNC:12731]",{"v":1.489792,"d":"1.49"},{"v":1.146382,"d":"1.15"},{"v":1.29955983258635,"d":"1.30"},{"v":0.378023057964369,"d":"0.38"},1,1,"up","no"]
[67383,0,"chr16","-",374005,375075,"ENST00000467452",3,646,"MSTRG.5482","TMEM8A","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0007155(cell adhesion);GO:0005765(lysosomal membrane);GO:0005515(protein binding);GO:0005887(integral component of plasma membrane);GO:0005886(plasma membrane);GO:0003674(molecular_function);GO:0008150(biological_process);GO:0070062(extracellular exosome)","NA","NA","NA","transmembrane protein 8A [Source:HGNC Symbol;Acc:HGNC:17205]",{"v":0.604646,"d":"0.60"},{"v":0.229027,"d":"0.23"},{"v":2.64006427189807,"d":"2.64"},{"v":1.40057305216703,"d":"1.40"},1,1,"up","no"]
[188089,0,"chr8","-",143706694,143708109,"ENST00000542437",2,1320,"ENSG00000255181","CCDC166","NA","NA","NA","NA","coiled-coil domain containing 166 [Source:HGNC Symbol;Acc:HGNC:41910]",0,{"v":0.029656,"d":"0.03"},"-inf","-inf",1,1,"down","no"]
[75424,0,"chr16","-",71859685,71883509,"ENST00000446827",6,1822,"MSTRG.6107","ZNF821","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0044212(transcription regulatory region DNA binding)","NA","NA","NA","zinc finger protein 821 [Source:HGNC Symbol;Acc:HGNC:28043]",{"v":0.143756,"d":"0.14"},0,"inf","inf",1,1,"up","no"]
[92877,0,"chr18","+",58323305,58334020,"ENST00000590020",5,710,"ENSG00000049759","NEDD4L","GO:0005737(cytoplasm);GO:0016740(transferase activity);GO:0016567(protein ubiquitination);GO:0005794(Golgi apparatus);GO:0004842(ubiquitin-protein transferase activity);GO:0005515(protein binding);GO:0006814(sodium ion transport);GO:0061630(ubiquitin protein ligase activity);GO:0006511(ubiquitin-dependent protein catabolic process);GO:0030154(cell differentiation);GO:0005768(endosome);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0034220(ion transmembrane transport);GO:0005622(intracellular);GO:0019058(viral life cycle);GO:0000209(protein polyubiquitination);GO:0016032(viral process);GO:0017080(sodium channel regulator activity);GO:0044325(ion channel binding);GO:0005886(plasma membrane);GO:0034765(regulation of ion transmembrane transport);GO:0042391(regulation of membrane potential);GO:1901016(regulation of potassium ion transmembrane transporter activity);GO:0045807(positive regulation of endocytosis);GO:0060306(regulation of membrane repolarization);GO:1901017(negative regulation of potassium ion transmembrane transporter activity);GO:0007588(excretion);GO:0030104(water homeostasis);GO:0015459(potassium channel regulator activity);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0005771(multivesicular body);GO:1903861(positive regulation of dendrite extension);GO:0042176(regulation of protein catabolic process);GO:0086005(ventricular cardiac muscle cell action potential);GO:2000009(negative regulation of protein localization to cell surface);GO:0019871(sodium channel inhibitor activity);GO:0042787(protein ubiquitination involved in ubiquitin-dependent protein catabolic process);GO:2000650(negative regulation of sodium ion transmembrane transporter activity);GO:0019870(potassium channel inhibitor activity);GO:1901380(negative regulation of potassium ion transmembrane transport);GO:0003254(regulation of membrane depolarization);GO:1902306(negative regulation of sodium ion transmembrane transport);GO:0006883(cellular sodium ion homeostasis);GO:0010038(response to metal ion);GO:0043161(proteasome-mediated ubiquitin-dependent protein catabolic process);GO:0070936(protein K48-linked ubiquitination);GO:2001288(positive regulation of caveolin-mediated endocytosis);GO:0006513(protein monoubiquitination);GO:0045732(positive regulation of protein catabolic process)","04120(Ubiquitin mediated proteolysis);04144(Endocytosis);04530(Tight junction);04960(Aldosterone-regulated sodium reabsorption)","NA","NA","neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase [Source:HGNC Symbol;Acc:HGNC:7728]",{"v":0.338026,"d":"0.34"},0,"inf","inf",1,1,"up","no"]
[30829,"j","chr11","-",64727054,64744867,"MSTRG.2519.9",18,2261,"MSTRG.2519","RASGRP2","NA","NA","NA","NA","NA",{"v":0.024533,"d":"0.02"},0,"inf","inf",1,1,"up","no"]
[88687,0,"chr17","-",77563368,77568695,"ENST00000585798",2,1767,"ENSG00000267466","AC021683.1","NA","NA","NA","NA","NA",0,{"v":0.02582,"d":"0.03"},"-inf","-inf",1,1,"down","no"]
[87770,0,"chr17","-",74862501,74872961,"ENST00000581530",12,1827,"ENSG00000161513","FDXR","GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0005739(mitochondrion);GO:0005759(mitochondrial matrix);GO:0015039(NADPH-adrenodoxin reductase activity);GO:0006629(lipid metabolic process);GO:0008202(steroid metabolic process);GO:0005515(protein binding);GO:0008203(cholesterol metabolic process);GO:0006091(generation of precursor metabolites and energy);GO:0006744(ubiquinone biosynthetic process);GO:0016125(sterol metabolic process);GO:0006700(C21-steroid hormone biosynthetic process);GO:0006694(steroid biosynthetic process);GO:0004324(ferredoxin-NADP+ reductase activity);GO:0070402(NADPH binding);GO:0070995(NADPH oxidation);GO:0005743(mitochondrial inner membrane)","NA","NA","NA","ferredoxin reductase [Source:HGNC Symbol;Acc:HGNC:3642]",0,{"v":0.013989,"d":"0.01"},"-inf","-inf",1,1,"down","no"]
[159496,0,"chr5","-",141672768,141673387,"ENST00000524066",2,533,"MSTRG.12405","ARAP3","GO:0007165(signal transduction);GO:0043547(positive regulation of GTPase activity);GO:0005096(GTPase activator activity);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0046872(metal ion binding);GO:0005886(plasma membrane);GO:0005856(cytoskeleton);GO:0042995(cell projection);GO:0005515(protein binding);GO:0016192(vesicle-mediated transport);GO:0005829(cytosol);GO:0030027(lamellipodium);GO:0051056(regulation of small GTPase mediated signal transduction);GO:0007010(cytoskeleton organization);GO:0005547(phosphatidylinositol-3,4,5-trisphosphate binding);GO:0043325(phosphatidylinositol-3,4-bisphosphate binding);GO:0008360(regulation of cell shape);GO:0001726(ruffle);GO:0030336(negative regulation of cell migration);GO:0035024(negative regulation of Rho protein signal transduction);GO:0035021(negative regulation of Rac protein signal transduction)","04015(Rap1 signaling pathway);04024(cAMP signaling pathway);04144(Endocytosis)","NA","NA","ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3 [Source:HGNC Symbol;Acc:HGNC:24097]",0,{"v":0.022455,"d":"0.02"},"-inf","-inf",1,1,"down","no"]
[3777,0,"chr1","-",31919247,31938042,"ENST00000494444",3,678,"MSTRG.357","PTP4A2","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0016787(hydrolase activity);GO:0004725(protein tyrosine phosphatase activity);GO:0016791(phosphatase activity);GO:0006470(protein dephosphorylation);GO:0016311(dephosphorylation);GO:0035335(peptidyl-tyrosine dephosphorylation);GO:0005886(plasma membrane);GO:0004721(phosphoprotein phosphatase activity);GO:0005634(nucleus);GO:0005768(endosome);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0043687(post-translational protein modification);GO:0005769(early endosome);GO:0004727(prenylated protein tyrosine phosphatase activity)","NA","NA","NA","protein tyrosine phosphatase type IVA, member 2 [Source:HGNC Symbol;Acc:HGNC:9635]",{"v":0.014484,"d":"0.01"},0,"inf","inf",1,1,"up","no"]
[170447,0,"chr6","+",157172776,157208685,"ENST00000636940",11,5910,"ENSG00000049618","ARID1B","GO:0005634(nucleus);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0016569(covalent chromatin modification);GO:0003677(DNA binding);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0007399(nervous system development);GO:0003713(transcription coactivator activity);GO:0006338(chromatin remodeling);GO:0090544(BAF-type complex);GO:0048096(chromatin-mediated maintenance of transcription);GO:0016514(SWI/SNF complex);GO:0007270(neuron-neuron synaptic transmission);GO:0060996(dendritic spine development);GO:0097026(dendritic cell dendrite assembly);GO:0071565(nBAF complex)","05225(Hepatocellular carcinoma)","NA","NA","AT-rich interaction domain 1B [Source:HGNC Symbol;Acc:HGNC:18040]",{"v":0.071,"d":"0.07"},{"v":0.103889,"d":"0.10"},{"v":0.683421728960718,"d":"0.68"},{"v":-0.549151976816528,"d":"-0.55"},1,1,"down","no"]
[68331,0,"chr16","-",2253126,2264331,"ENST00000566397",6,1685,"MSTRG.5535","RNPS1","GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0006397(mRNA processing);GO:0008380(RNA splicing);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016607(nuclear speck);GO:0005654(nucleoplasm);GO:0005515(protein binding);GO:0005829(cytosol);GO:0043065(positive regulation of apoptotic process);GO:0006369(termination of RNA polymerase II transcription);GO:0006405(RNA export from nucleus);GO:0031124(mRNA 3'-end processing);GO:0035145(exon-exon junction complex);GO:0000381(regulation of alternative mRNA splicing, via spliceosome);GO:0048025(negative regulation of mRNA splicing, via spliceosome);GO:0061574(ASAP complex);GO:0003730(mRNA 3'-UTR binding);GO:0000398(mRNA splicing, via spliceosome);GO:0000184(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay);GO:0006406(mRNA export from nucleus);GO:0006351(transcription, DNA-templated)","03013(RNA transport);03015(mRNA surveillance pathway)","NA","NA","RNA binding protein with serine rich domain 1 [Source:HGNC Symbol;Acc:HGNC:10080]",0,{"v":0.017214,"d":"0.02"},"-inf","-inf",1,1,"down","no"]
[67666,0,"chr16","-",729766,740934,"ENST00000540986",10,3212,"ENSG00000103245","NARFL","GO:0046872(metal ion binding);GO:0055114(oxidation-reduction process);GO:0051536(iron-sulfur cluster binding);GO:0051539(4 iron, 4 sulfur cluster binding);GO:0016226(iron-sulfur cluster assembly);GO:0097361(CIA complex);GO:0010468(regulation of gene expression);GO:0001666(response to hypoxia);GO:0032364(oxygen homeostasis);GO:0003954(NADH dehydrogenase activity);GO:0002244(hematopoietic progenitor cell differentiation)","NA","NA","NA","nuclear prelamin A recognition factor like [Source:HGNC Symbol;Acc:HGNC:14179]",{"v":0.014296,"d":"0.01"},{"v":0.028535,"d":"0.03"},{"v":0.500998773436131,"d":"0.50"},{"v":-0.997121023522322,"d":"-1.00"},1,1,"down","no"]
[200677,0,"chrX","+",150985531,150987297,"ENST00000430118",3,529,"ENSG00000029993","HMGB3","GO:0005634(nucleus);GO:0003677(DNA binding);GO:0003723(RNA binding);GO:0005737(cytoplasm);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0005694(chromosome);GO:0005515(protein binding);GO:0006310(DNA recombination);GO:0002376(immune system process);GO:0045087(innate immune response);GO:0000400(four-way junction DNA binding);GO:0008301(DNA binding, bending);GO:0032392(DNA geometric change);GO:0003690(double-stranded DNA binding);GO:0007275(multicellular organism development);GO:0045578(negative regulation of B cell differentiation);GO:0045638(negative regulation of myeloid cell differentiation)","NA","NA","NA","high mobility group box 3 [Source:HGNC Symbol;Acc:HGNC:5004]",{"v":3.771E-3,"d":"0.00"},0,"inf","inf",1,1,"up","no"]
[130851,0,"chr22","-",36286847,36286907,"ENST00000622122",1,61,"MSTRG.10417","MIR6819","NA","NA","NA","NA","microRNA 6819 [Source:HGNC Symbol;Acc:HGNC:50155]",{"v":0.370189,"d":"0.37"},{"v":0.037397,"d":"0.04"},{"v":9.89889563333957,"d":"9.90"},{"v":3.30726758042689,"d":"3.31"},1,1,"up","no"]
[158749,0,"chr5","-",138167987,138178629,"ENST00000428808",9,754,"ENSG00000112983","BRD8","GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0016569(covalent chromatin modification);GO:0005739(mitochondrion);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0030522(intracellular receptor signaling pathway);GO:0040008(regulation of growth);GO:0007165(signal transduction);GO:0043967(histone H4 acetylation);GO:0007166(cell surface receptor signaling pathway);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0043968(histone H2A acetylation);GO:0035267(NuA4 histone acetyltransferase complex);GO:0004887(thyroid hormone receptor activity);GO:0000812(Swr1 complex);GO:0045944(positive regulation of transcription from RNA polymerase II promoter)","NA","NA","NA","bromodomain containing 8 [Source:HGNC Symbol;Acc:HGNC:19874]",{"v":1E-4,"d":"0.00"},{"v":0.219509,"d":"0.22"},{"v":4.5556218651627E-4,"d":"0.00"},{"v":-11.100064376993,"d":"-11.10"},1,1,"down","no"]
[41746,0,"chr12","+",51494873,51497233,"ENST00000546872",2,493,"ENSG00000050438","SLC4A8","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005215(transporter activity);GO:0055085(transmembrane transport);GO:0006811(ion transport);GO:0015297(antiporter activity);GO:0006814(sodium ion transport);GO:0035725(sodium ion transmembrane transport);GO:0008509(anion transmembrane transporter activity);GO:0006820(anion transport);GO:0098656(anion transmembrane transport);GO:0005452(inorganic anion exchanger activity);GO:0015698(inorganic anion transport);GO:0005886(plasma membrane);GO:0005887(integral component of plasma membrane);GO:0051453(regulation of intracellular pH);GO:0015701(bicarbonate transport);GO:0008510(sodium:bicarbonate symporter activity);GO:0015301(anion:anion antiporter activity);GO:0032809(neuronal cell body membrane);GO:0043005(neuron projection)","NA","NA","NA","solute carrier family 4 member 8 [Source:HGNC Symbol;Acc:HGNC:11034]",0,{"v":0.034575,"d":"0.03"},"-inf","-inf",1,1,"down","no"]
[103512,0,"chr19","+",48394875,48444931,"ENST00000263269",13,5093,"ENSG00000105464","GRIN2D","GO:0005622(intracellular);GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005216(ion channel activity);GO:0006811(ion transport);GO:0034220(ion transmembrane transport);GO:0005886(plasma membrane);GO:0043547(positive regulation of GTPase activity);GO:0005515(protein binding);GO:0030054(cell junction);GO:0045202(synapse);GO:0045211(postsynaptic membrane);GO:0004872(receptor activity);GO:0004970(ionotropic glutamate receptor activity);GO:0005234(extracellular-glutamate-gated ion channel activity);GO:0035235(ionotropic glutamate receptor signaling pathway);GO:0060079(excitatory postsynaptic potential);GO:0000165(MAPK cascade);GO:0034765(regulation of ion transmembrane transport);GO:0007165(signal transduction);GO:0005088(Ras guanyl-nucleotide exchange factor activity);GO:0004972(NMDA glutamate receptor activity);GO:0001964(startle response);GO:0008344(adult locomotory behavior);GO:0051930(regulation of sensory perception of pain)","04020(Calcium signaling pathway);04024(cAMP signaling pathway);04080(Neuroactive ligand-receptor interaction);04724(Glutamatergic synapse);04720(Long-term potentiation);04713(Circadian entrainment);05010(Alzheimer's disease);05014(Amyotrophic lateral sclerosis (ALS));05030(Cocaine addiction);05031(Amphetamine addiction);05033(Nicotine addiction);05034(Alcoholism)","K05212","NA","glutamate ionotropic receptor NMDA type subunit 2D [Source:HGNC Symbol;Acc:HGNC:4588]",{"v":0.049679,"d":"0.05"},{"v":0.146955,"d":"0.15"},{"v":0.338055867442414,"d":"0.34"},{"v":-1.56466640748712,"d":"-1.56"},1,1,"down","no"]
[55447,0,"chr14","+",58298556,58372226,"ENST00000395168",24,4051,"MSTRG.4447","ARID4A","GO:0005634(nucleus);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0016575(histone deacetylation);GO:0003677(DNA binding);GO:0005886(plasma membrane);GO:0006349(regulation of gene expression by genetic imprinting);GO:0007283(spermatogenesis);GO:0034773(histone H4-K20 trimethylation);GO:0036124(histone H3-K9 trimethylation);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0048821(erythrocyte development);GO:0080182(histone H3-K4 trimethylation);GO:0097368(establishment of Sertoli cell barrier);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0006366(transcription from RNA polymerase II promoter);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0004407(histone deacetylase activity);GO:0044212(transcription regulatory region DNA binding);GO:0045892(negative regulation of transcription, DNA-templated);GO:0017053(transcriptional repressor complex)","NA","NA","NA","AT-rich interaction domain 4A [Source:HGNC Symbol;Acc:HGNC:9885]",{"v":0.063675,"d":"0.06"},{"v":0.04192,"d":"0.04"},{"v":1.51896469465649,"d":"1.52"},{"v":0.603088337624107,"d":"0.60"},1,1,"up","no"]
[412,0,"chr1","-",1386482,1398304,"ENST00000482621",10,2059,"MSTRG.57","CCNL2","GO:0005634(nucleus);GO:0016607(nuclear speck);GO:0043231(intracellular membrane-bounded organelle);GO:0005654(nucleoplasm);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0005515(protein binding);GO:0019901(protein kinase binding);GO:0000079(regulation of cyclin-dependent protein serine/threonine kinase activity);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0016538(cyclin-dependent protein serine/threonine kinase regulator activity);GO:0045737(positive regulation of cyclin-dependent protein serine/threonine kinase activity);GO:1901409(positive regulation of phosphorylation of RNA polymerase II C-terminal domain);GO:0000307(cyclin-dependent protein kinase holoenzyme complex)","NA","NA","NA","cyclin L2 [Source:HGNC Symbol;Acc:HGNC:20570]",{"v":0.232007,"d":"0.23"},{"v":0.249388,"d":"0.25"},{"v":0.930305387588817,"d":"0.93"},{"v":-0.104223713249356,"d":"-0.10"},1,1,"down","no"]
[113993,0,"chr2","+",120213344,120213631,"ENST00000429447",1,288,"ENSG00000243104","MTND4LP14","NA","NA","NA","NA","mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 4L pseudogene 14 [Source:HGNC Symbol;Acc:HGNC:42248]",{"v":0.356959,"d":"0.36"},0,"inf","inf",1,1,"up","no"]
[184617,0,"chr8","+",70608682,70646490,"ENST00000518152",3,784,"MSTRG.14390","LACTB2-AS1","NA","NA","NA","NA","LACTB2 antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:27841]",0,0,1,0,1,1,"no","no"]
[18917,0,"chr10","-",18651266,18659267,"ENST00000456217",3,392,"ENSG00000241058","NSUN6","GO:0003723(RNA binding);GO:0008168(methyltransferase activity);GO:0016740(transferase activity);GO:0032259(methylation);GO:0030488(tRNA methylation);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0006400(tRNA modification);GO:0016428(tRNA (cytosine-5-)-methyltransferase activity);GO:0000049(tRNA binding)","NA","NA","NA","NOP2/Sun RNA methyltransferase family member 6 [Source:HGNC Symbol;Acc:HGNC:23529]",0,{"v":0.148447,"d":"0.15"},"-inf","-inf",1,1,"down","no"]
[71462,0,"chr16","-",29217170,29220031,"ENST00000566070",2,2099,"ENSG00000259807","AC009093.1","NA","NA","NA","NA","NA",{"v":0.07345,"d":"0.07"},{"v":0.127938,"d":"0.13"},{"v":0.574106207694352,"d":"0.57"},{"v":-0.800610439624046,"d":"-0.80"},1,1,"down","no"]
[44799,0,"chr12","+",80209453,80379090,"ENST00000458043",58,8083,"ENSG00000165899","OTOGL","GO:0007605(sensory perception of sound);GO:0005576(extracellular region);GO:0046556(alpha-L-arabinofuranosidase activity);GO:0046373(L-arabinose metabolic process)","NA","NA","NA","otogelin like [Source:HGNC Symbol;Acc:HGNC:26901]",{"v":0.015329,"d":"0.02"},{"v":0.021469,"d":"0.02"},{"v":0.714006241557595,"d":"0.71"},{"v":-0.485991409113615,"d":"-0.49"},1,1,"down","no"]
[175016,0,"chr7","+",74094233,74105905,"ENST00000491052",5,587,"MSTRG.13710","LIMK1","GO:0016607(nuclear speck);GO:0046872(metal ion binding);GO:0004672(protein kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0005829(cytosol);GO:0005737(cytoplasm);GO:0005634(nucleus);GO:0000166(nucleotide binding);GO:0004674(protein serine/threonine kinase activity);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0005515(protein binding);GO:0038096(Fc-gamma receptor signaling pathway involved in phagocytosis);GO:0045773(positive regulation of axon extension);GO:0005794(Golgi apparatus);GO:0004871(signal transducer activity);GO:0043005(neuron projection);GO:0007399(nervous system development);GO:0007165(signal transduction);GO:0007266(Rho protein signal transduction);GO:0030036(actin cytoskeleton organization);GO:0051444(negative regulation of ubiquitin-protein transferase activity);GO:0032233(positive regulation of actin filament bundle assembly);GO:0031072(heat shock protein binding);GO:0046982(protein heterodimerization activity);GO:0051496(positive regulation of stress fiber assembly);GO:0005925(focal adhesion);GO:0016020(membrane)","04810(Regulation of actin cytoskeleton);04666(Fc gamma R-mediated phagocytosis);04360(Axon guidance)","NA","NA","LIM domain kinase 1 [Source:HGNC Symbol;Acc:HGNC:6613]",{"v":0.010437,"d":"0.01"},0,"inf","inf",1,1,"up","no"]
[114576,0,"chr2","+",131527834,131533664,"ENST00000467992",7,1347,"ENSG00000163040","CCDC74A","NA","NA","NA","NA","coiled-coil domain containing 74A [Source:HGNC Symbol;Acc:HGNC:25197]",{"v":0.134544,"d":"0.13"},0,"inf","inf",1,1,"up","no"]
[145779,0,"chr4","-",7809439,7816048,"ENST00000614385",2,356,"ENSG00000196526","AFAP1","GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0003779(actin binding);GO:0005925(focal adhesion);GO:0015629(actin cytoskeleton);GO:0005856(cytoskeleton);GO:0009966(regulation of signal transduction);GO:0051493(regulation of cytoskeleton organization)","NA","NA","NA","actin filament associated protein 1 [Source:HGNC Symbol;Acc:HGNC:24017]",{"v":0.091927,"d":"0.09"},{"v":0.207612,"d":"0.21"},{"v":0.442782690788586,"d":"0.44"},{"v":-1.17532926933872,"d":"-1.18"},1,1,"down","no"]
[126771,0,"chr21","-",33596062,33603448,"ENST00000414079",4,408,"MSTRG.10039","CRYZL1","GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0005829(cytosol);GO:0050661(NADP binding);GO:0003960(NADPH:quinone reductase activity);GO:1901661(quinone metabolic process)","NA","NA","NA","crystallin zeta like 1 [Source:HGNC Symbol;Acc:HGNC:2420]",0,0,1,0,1,1,"no","no"]
[93439,0,"chr18","-",74389884,74390297,"ENST00000474180",1,414,"ENSG00000235297","AC008021.1","NA","NA","NA","NA","NA",{"v":0.517538,"d":"0.52"},0,"inf","inf",1,1,"up","no"]
[88120,0,"chr17","+",75646437,75647977,"ENST00000579469",2,957,"MSTRG.7221","SMIM6","GO:0016020(membrane);GO:0016021(integral component of membrane)","NA","NA","NA","small integral membrane protein 6 [Source:HGNC Symbol;Acc:HGNC:40032]",0,0,1,0,1,1,"no","no"]
[101375,0,"chr19","-",39825715,39831867,"ENST00000597639",11,1806,"MSTRG.8126","DYRK1B","GO:0005634(nucleus);GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0004713(protein tyrosine kinase activity);GO:0018108(peptidyl-tyrosine phosphorylation);GO:0007520(myoblast fusion);GO:0005515(protein binding);GO:0003713(transcription coactivator activity);GO:0045893(positive regulation of transcription, DNA-templated);GO:0060612(adipose tissue development);GO:0004712(protein serine/threonine/tyrosine kinase activity)","NA","NA","NA","dual specificity tyrosine phosphorylation regulated kinase 1B [Source:HGNC Symbol;Acc:HGNC:3092]",0,0,1,0,1,1,"no","no"]
[30083,0,"chr11","+",61840297,61863077,"ENST00000521571",5,799,"MSTRG.2455","FADS2","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0006629(lipid metabolic process);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0006631(fatty acid metabolic process);GO:0006633(fatty acid biosynthetic process);GO:0006636(unsaturated fatty acid biosynthetic process);GO:0005887(integral component of plasma membrane);GO:0036109(alpha-linolenic acid metabolic process);GO:0043651(linoleic acid metabolic process);GO:0016213(linoleoyl-CoA desaturase activity);GO:0004768(stearoyl-CoA 9-desaturase activity)","00592(alpha-Linolenic acid metabolism);01040(Biosynthesis of unsaturated fatty acids);03320(PPAR signaling pathway)","NA","NA","fatty acid desaturase 2 [Source:HGNC Symbol;Acc:HGNC:3575]",0,{"v":0.413528,"d":"0.41"},"-inf","-inf",1,1,"down","no"]
[90804,0,"chr18","+",11981465,12030868,"ENST00000590107",8,1616,"MSTRG.7420","IMPA2","GO:0046872(metal ion binding);GO:0016787(hydrolase activity);GO:0046854(phosphatidylinositol phosphorylation);GO:0008934(inositol monophosphate 1-phosphatase activity);GO:0052832(inositol monophosphate 3-phosphatase activity);GO:0052833(inositol monophosphate 4-phosphatase activity);GO:0052834(inositol monophosphate phosphatase activity);GO:0006021(inositol biosynthetic process);GO:0046855(inositol phosphate dephosphorylation);GO:0005515(protein binding);GO:0005829(cytosol);GO:0007165(signal transduction);GO:0005737(cytoplasm);GO:0006796(phosphate-containing compound metabolic process);GO:0042803(protein homodimerization activity);GO:0006020(inositol metabolic process);GO:0043647(inositol phosphate metabolic process)","00562(Inositol phosphate metabolism);04070(Phosphatidylinositol signaling system)","NA","NA","inositol monophosphatase 2 [Source:HGNC Symbol;Acc:HGNC:6051]",{"v":0.006974,"d":"0.01"},{"v":0.020146,"d":"0.02"},{"v":0.346172937555842,"d":"0.35"},{"v":-1.5304351500212,"d":"-1.53"},1,1,"down","no"]
[21085,0,"chr10","-",72088357,72089032,"ENST00000483699",2,300,"MSTRG.1761","SPOCK2","GO:0005509(calcium ion binding);GO:0007165(signal transduction);GO:0005576(extracellular region);GO:0005578(proteinaceous extracellular matrix);GO:0045595(regulation of cell differentiation);GO:0007416(synapse assembly);GO:0030198(extracellular matrix organization);GO:0005539(glycosaminoglycan binding);GO:0008191(metalloendopeptidase inhibitor activity);GO:0050840(extracellular matrix binding);GO:0010811(positive regulation of cell-substrate adhesion);GO:0010951(negative regulation of endopeptidase activity);GO:0019800(peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan);GO:1990830(cellular response to leukemia inhibitory factor);GO:2000147(positive regulation of cell motility)","NA","NA","NA","SPARC/osteonectin, cwcv and kazal like domains proteoglycan 2 [Source:HGNC Symbol;Acc:HGNC:13564]",0,{"v":0.000802,"d":"0.00"},"-inf","-inf",1,1,"down","no"]
[189831,0,"chr9","-",34613551,34616743,"ENST00000479399",2,3023,"MSTRG.14741","DCTN3","GO:0005737(cytoplasm);GO:0005730(nucleolus);GO:0005829(cytosol);GO:0051301(cell division);GO:0005694(chromosome);GO:0005856(cytoskeleton);GO:0007049(cell cycle);GO:0048471(perinuclear region of cytoplasm);GO:0005813(centrosome);GO:0005815(microtubule organizing center);GO:0005819(spindle);GO:0030496(midbody);GO:0000775(chromosome, centromeric region);GO:0000776(kinetochore);GO:0000777(condensed chromosome kinetochore);GO:0005515(protein binding);GO:0032154(cleavage furrow);GO:0000086(G2/M transition of mitotic cell cycle);GO:0010389(regulation of G2/M transition of mitotic cell cycle);GO:0097711(ciliary basal body docking);GO:0019886(antigen processing and presentation of exogenous peptide antigen via MHC class II);GO:0006888(ER to Golgi vesicle-mediated transport);GO:0005198(structural molecule activity);GO:0000910(cytokinesis);GO:0000278(mitotic cell cycle);GO:0005869(dynactin complex);GO:0007017(microtubule-based process);GO:0005875(microtubule associated complex)","NA","NA","NA","dynactin subunit 3 [Source:HGNC Symbol;Acc:HGNC:2713]",0,{"v":0.281441,"d":"0.28"},"-inf","-inf",1,1,"down","no"]
[89979,0,"chr17","-",82657911,82698662,"ENST00000538809",6,704,"ENSG00000141542","RAB40B","GO:0016020(membrane);GO:0005525(GTP binding);GO:0000166(nucleotide binding);GO:0016567(protein ubiquitination);GO:0035556(intracellular signal transduction);GO:0003924(GTPase activity);GO:0005886(plasma membrane);GO:0005768(endosome);GO:0048471(perinuclear region of cytoplasm);GO:1990967(multi-organism toxin transport);GO:0008021(synaptic vesicle);GO:0072659(protein localization to plasma membrane);GO:0030667(secretory granule membrane);GO:0005635(nuclear envelope);GO:0005622(intracellular)","NA","NA","NA","RAB40B, member RAS oncogene family [Source:HGNC Symbol;Acc:HGNC:18284]",0,0,1,0,1,1,"no","no"]
[146328,0,"chr4","+",20700459,20704524,"ENST00000511160",4,556,"ENSG00000163138","PACRGL","GO:0005515(protein binding)","NA","NA","NA","parkin coregulated like [Source:HGNC Symbol;Acc:HGNC:28442]",{"v":0.019791,"d":"0.02"},0,"inf","inf",1,1,"up","no"]
[183081,0,"chr8","+",38386441,38408544,"ENST00000297720",10,1693,"ENSG00000165046","LETM2","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005743(mitochondrial inner membrane);GO:0005739(mitochondrion);GO:0043022(ribosome binding);GO:0006875(cellular metal ion homeostasis);GO:0003824(catalytic activity)","NA","NA","NA","leucine zipper and EF-hand containing transmembrane protein 2 [Source:HGNC Symbol;Acc:HGNC:14648]",0,{"v":0.227101,"d":"0.23"},"-inf","-inf",1,1,"down","no"]
[184143,0,"chr8","+",60517176,60559279,"ENST00000481569",2,506,"MSTRG.14371","RAB2A","GO:0006810(transport);GO:0005634(nucleus);GO:0016020(membrane);GO:0015031(protein transport);GO:0005525(GTP binding);GO:0000166(nucleotide binding);GO:0003924(GTPase activity);GO:0005794(Golgi apparatus);GO:0005765(lysosomal membrane);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005515(protein binding);GO:0042470(melanosome);GO:0000139(Golgi membrane);GO:0016192(vesicle-mediated transport);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0043687(post-translational protein modification);GO:0019003(GDP binding);GO:0007030(Golgi organization);GO:0006888(ER to Golgi vesicle-mediated transport);GO:0033116(endoplasmic reticulum-Golgi intermediate compartment membrane)","04152(AMPK signaling pathway)","NA","NA","RAB2A, member RAS oncogene family [Source:HGNC Symbol;Acc:HGNC:9763]",{"v":0.112287,"d":"0.11"},{"v":0.171948,"d":"0.17"},{"v":0.653028822667318,"d":"0.65"},{"v":-0.614781425624792,"d":"-0.61"},1,1,"down","no"]
[59144,0,"chr14","+",103699922,103701544,"ENST00000556986",2,1150,"MSTRG.4713","KLC1","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0003777(microtubule motor activity);GO:0005871(kinesin complex);GO:0005856(cytoskeleton);GO:0042995(cell projection);GO:0005515(protein binding);GO:0005874(microtubule);GO:0031410(cytoplasmic vesicle);GO:0005829(cytosol);GO:0030426(growth cone);GO:0006890(retrograde vesicle-mediated transport, Golgi to ER);GO:0016032(viral process);GO:0003774(motor activity);GO:0007018(microtubule-based movement);GO:0019886(antigen processing and presentation of exogenous peptide antigen via MHC class II);GO:0035617(stress granule disassembly)","05132(Salmonella infection)","NA","NA","kinesin light chain 1 [Source:HGNC Symbol;Acc:HGNC:6387]",{"v":1.099795,"d":"1.10"},{"v":0.190785,"d":"0.19"},{"v":5.76457792803417,"d":"5.76"},{"v":2.52721498022336,"d":"2.53"},1,1,"up","no"]
[71392,0,"chr16","-",28914259,28924937,"ENST00000567483",5,841,"ENSG00000177548","RABEP2","GO:0006810(transport);GO:0005737(cytoplasm);GO:0015031(protein transport);GO:0043231(intracellular membrane-bounded organelle);GO:0005829(cytosol);GO:0006897(endocytosis);GO:0008083(growth factor activity);GO:0043547(positive regulation of GTPase activity);GO:0005096(GTPase activator activity);GO:0005768(endosome);GO:0005769(early endosome)","NA","NA","NA","rabaptin, RAB GTPase binding effector protein 2 [Source:HGNC Symbol;Acc:HGNC:24817]",{"v":0.082412,"d":"0.08"},0,"inf","inf",1,1,"up","no"]
[74427,0,"chr16","+",67287572,67289307,"ENST00000562289",4,1298,"ENSG00000196155","PLEKHG4","GO:0005089(Rho guanyl-nucleotide exchange factor activity);GO:0035023(regulation of Rho protein signal transduction);GO:0005515(protein binding);GO:0005085(guanyl-nucleotide exchange factor activity);GO:0090630(activation of GTPase activity)","NA","NA","NA","pleckstrin homology and RhoGEF domain containing G4 [Source:HGNC Symbol;Acc:HGNC:24501]",{"v":0.267094,"d":"0.27"},0,"inf","inf",1,1,"up","no"]
[97930,0,"chr19","+",16081723,16093581,"ENST00000592138",5,635,"MSTRG.7926","TPM4","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0046872(metal ion binding);GO:0003779(actin binding);GO:0042803(protein homodimerization activity);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0005925(focal adhesion);GO:0005509(calcium ion binding);GO:0005829(cytosol);GO:0051015(actin filament binding);GO:0070062(extracellular exosome);GO:0007015(actin filament organization);GO:0042802(identical protein binding);GO:0046982(protein heterodimerization activity);GO:0001725(stress fiber);GO:0006936(muscle contraction);GO:0006928(movement of cell or subcellular component);GO:0008307(structural constituent of muscle);GO:0030049(muscle filament sliding);GO:0001649(osteoblast differentiation);GO:0005884(actin filament);GO:0005862(muscle thin filament tropomyosin);GO:0002102(podosome);GO:0015629(actin cytoskeleton);GO:0030863(cortical cytoskeleton);GO:0031941(filamentous actin)","04260(Cardiac muscle contraction);04261(Adrenergic signaling in cardiomyocytes);05410(Hypertrophic cardiomyopathy (HCM));05414(Dilated cardiomyopathy (DCM))","NA","NA","tropomyosin 4 [Source:HGNC Symbol;Acc:HGNC:12013]",{"v":2.58316,"d":"2.58"},{"v":0.653852,"d":"0.65"},{"v":3.95067997039085,"d":"3.95"},{"v":1.98210098379216,"d":"1.98"},1,1,"up","no"]
[89285,0,"chr17","-",81251196,81295267,"ENST00000288439",14,2708,"MSTRG.7319","SLC38A10","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005794(Golgi apparatus);GO:0006811(ion transport);GO:0006814(sodium ion transport);GO:0015171(amino acid transmembrane transporter activity);GO:0003333(amino acid transmembrane transport);GO:0006865(amino acid transport);GO:0060348(bone development)","NA","NA","NA","solute carrier family 38 member 10 [Source:HGNC Symbol;Acc:HGNC:28237]",0,0,1,0,1,1,"no","no"]
[68320,0,"chr16","-",2239895,2251572,"ENST00000562238",7,948,"MSTRG.5533","ECI1","GO:0016853(isomerase activity);GO:0003824(catalytic activity);GO:0006629(lipid metabolic process);GO:0008152(metabolic process);GO:0006631(fatty acid metabolic process);GO:0005739(mitochondrion);GO:0005759(mitochondrial matrix);GO:0070062(extracellular exosome);GO:0006635(fatty acid beta-oxidation);GO:0004165(dodecenoyl-CoA delta-isomerase activity);GO:0004300(enoyl-CoA hydratase activity);GO:0016860(intramolecular oxidoreductase activity);GO:0005743(mitochondrial inner membrane)","00071(Fatty acid degradation)","K13238","EC:5.3.3.8","enoyl-CoA delta isomerase 1 [Source:HGNC Symbol;Acc:HGNC:2703]",0,0,1,0,1,1,"no","no"]
[43502,0,"chr12","-",57534978,57547188,"ENST00000547345",5,566,"MSTRG.3495","DCTN2","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005829(cytosol);GO:0005813(centrosome);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0005874(microtubule);GO:0003774(motor activity);GO:0005815(microtubule organizing center);GO:0007017(microtubule-based process);GO:0042802(identical protein binding);GO:0000776(kinetochore);GO:0000278(mitotic cell cycle);GO:0005869(dynactin complex);GO:0030286(dynein complex);GO:0070062(extracellular exosome);GO:0008283(cell proliferation);GO:0000086(G2/M transition of mitotic cell cycle);GO:0010389(regulation of G2/M transition of mitotic cell cycle);GO:0097711(ciliary basal body docking);GO:0019886(antigen processing and presentation of exogenous peptide antigen via MHC class II);GO:0031982(vesicle);GO:0006888(ER to Golgi vesicle-mediated transport);GO:0030507(spectrin binding);GO:0007052(mitotic spindle organization);GO:0071539(protein localization to centrosome);GO:0032402(melanosome transport);GO:0030426(growth cone)","04962(Vasopressin-regulated water reabsorption);05016(Huntington's disease)","NA","NA","dynactin subunit 2 [Source:HGNC Symbol;Acc:HGNC:2712]",{"v":0.151313,"d":"0.15"},{"v":0.042864,"d":"0.04"},{"v":3.53007185516984,"d":"3.53"},{"v":1.81969755008063,"d":"1.82"},1,1,"up","no"]
[81138,0,"chr17","+",28340406,28342512,"ENST00000577535",4,482,"MSTRG.6547","TNFAIP1","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005730(nucleolus);GO:0016567(protein ubiquitination);GO:0051260(protein homooligomerization);GO:0005515(protein binding);GO:0006955(immune response);GO:0006915(apoptotic process);GO:0006260(DNA replication);GO:0005768(endosome);GO:0004842(ubiquitin-protein transferase activity);GO:0043161(proteasome-mediated ubiquitin-dependent protein catabolic process);GO:0016477(cell migration);GO:0009790(embryo development);GO:0017049(GTP-Rho binding);GO:0031463(Cul3-RING ubiquitin ligase complex);GO:0043149(stress fiber assembly);GO:0035024(negative regulation of Rho protein signal transduction);GO:0019904(protein domain specific binding);GO:0045740(positive regulation of DNA replication)","NA","NA","NA","TNF alpha induced protein 1 [Source:HGNC Symbol;Acc:HGNC:11894]",{"v":0.556254,"d":"0.56"},0,"inf","inf",1,1,"up","no"]
[124355,0,"chr20","-",46386124,46406624,"ENST00000497412",8,777,"MSTRG.9797","ELMO2","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005829(cytosol);GO:0006915(apoptotic process);GO:0016477(cell migration);GO:0038096(Fc-gamma receptor signaling pathway involved in phagocytosis);GO:0007010(cytoskeleton organization);GO:0005515(protein binding);GO:0017124(SH3 domain binding);GO:0098609(cell-cell adhesion);GO:0006909(phagocytosis);GO:0030971(receptor tyrosine kinase binding);GO:0048010(vascular endothelial growth factor receptor signaling pathway);GO:0060326(cell chemotaxis);GO:0016021(integral component of membrane)","05131(Shigellosis);05100(Bacterial invasion of epithelial cells)","NA","NA","engulfment and cell motility 2 [Source:HGNC Symbol;Acc:HGNC:17233]",0,0,1,0,1,1,"no","no"]
[94237,0,"chr19","+",1269335,1274810,"ENST00000587169",6,3028,"MSTRG.7603","CIRBP","GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005730(nucleolus);GO:0005515(protein binding);GO:0005654(nucleoplasm);GO:0045727(positive regulation of translation);GO:0010494(cytoplasmic stress granule);GO:0009411(response to UV);GO:0003730(mRNA 3'-UTR binding);GO:0034063(stress granule assembly);GO:0030371(translation repressor activity);GO:0048255(mRNA stabilization);GO:0009409(response to cold);GO:0070181(small ribosomal subunit rRNA binding);GO:0017148(negative regulation of translation)","NA","NA","NA","cold inducible RNA binding protein [Source:HGNC Symbol;Acc:HGNC:1982]",{"v":0.033589,"d":"0.03"},{"v":0.081768,"d":"0.08"},{"v":0.410784169846395,"d":"0.41"},{"v":-1.28354750847017,"d":"-1.28"},1,1,"down","no"]
[197034,0,"chrX","+",48806419,48806959,"ENST00000461608",2,397,"MSTRG.15283","HDAC6","GO:0048471(perinuclear region of cytoplasm);GO:0010634(positive regulation of epithelial cell migration);GO:1901300(positive regulation of hydrogen peroxide-mediated programmed cell death);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0005654(nucleoplasm);GO:0004407(histone deacetylase activity);GO:0008017(microtubule binding);GO:0016787(hydrolase activity);GO:0032041(NAD-dependent histone deacetylase activity (H3-K14 specific));GO:0042903(tubulin deacetylase activity);GO:0043130(ubiquitin binding);GO:0048487(beta-tubulin binding);GO:0000209(protein polyubiquitination);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0006476(protein deacetylation);GO:0006511(ubiquitin-dependent protein catabolic process);GO:0007026(negative regulation of microtubule depolymerization);GO:0016569(covalent chromatin modification);GO:0016575(histone deacetylation);GO:0043162(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway);GO:0043241(protein complex disassembly);GO:0045598(regulation of fat cell differentiation);GO:0048668(collateral sprouting);GO:0051646(mitochondrion localization);GO:0060997(dendritic spine morphogenesis);GO:0070201(regulation of establishment of protein localization);GO:0070842(aggresome assembly);GO:0070846(Hsp90 deacetylation);GO:0070932(histone H3 deacetylation);GO:0071218(cellular response to misfolded protein);GO:0090042(tubulin deacetylation);GO:0098779(positive regulation of macromitophagy in response to mitochondrial depolarization);GO:0005829(cytosol);GO:0005881(cytoplasmic microtubule);GO:0030424(axon);GO:0030425(dendrite);GO:0043005(neuron projection);GO:0043204(perikaryon);GO:0043234(protein complex);GO:0044297(cell body);GO:0003779(actin binding);GO:0042995(cell projection);GO:0005515(protein binding);GO:0005874(microtubule);GO:0006914(autophagy);GO:0001047(core promoter binding);GO:0000118(histone deacetylase complex);GO:1903146(regulation of mitophagy);GO:0019899(enzyme binding);GO:0045892(negative regulation of transcription, DNA-templated);GO:0051879(Hsp90 protein binding);GO:0043242(negative regulation of protein complex disassembly);GO:0008013(beta-catenin binding);GO:0031625(ubiquitin protein ligase binding);GO:0042826(histone deacetylase binding);GO:0031647(regulation of protein stability);GO:0061734(parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization);GO:0016235(aggresome);GO:0005901(caveola);GO:0040029(regulation of gene expression, epigenetic);GO:0045861(negative regulation of proteolysis);GO:0051354(negative regulation of oxidoreductase activity);GO:0051788(response to misfolded protein);GO:0010469(regulation of receptor activity);GO:0048156(tau protein binding);GO:0010506(regulation of autophagy);GO:0070301(cellular response to hydrogen peroxide);GO:0010870(positive regulation of receptor biosynthetic process);GO:0016234(inclusion body);GO:0009636(response to toxic substance);GO:0070840(dynein complex binding);GO:0060765(regulation of androgen receptor signaling pathway);GO:0031252(cell leading edge);GO:0043014(alpha-tubulin binding);GO:0005875(microtubule associated complex);GO:0031593(polyubiquitin binding);GO:0034983(peptidyl-lysine deacetylation);GO:0009967(positive regulation of signal transduction);GO:0060271(cilium assembly);GO:0006886(intracellular protein transport);GO:0005771(multivesicular body);GO:0030286(dynein complex);GO:0051787(misfolded protein binding);GO:0006515(misfolded or incompletely synthesized protein catabolic process);GO:0010033(response to organic substance);GO:0010727(negative regulation of hydrogen peroxide metabolic process);GO:0016241(regulation of macroautophagy);GO:0032418(lysosome localization);GO:0035967(cellular response to topologically incorrect protein);GO:0060632(regulation of microtubule-based movement);GO:0070845(polyubiquitinated misfolded protein transport);GO:0070848(response to growth factor);GO:0090035(positive regulation of chaperone-mediated protein complex assembly)","05203(Viral carcinogenesis);05034(Alcoholism);05165(Human papillomavirus infection)","NA","NA","histone deacetylase 6 [Source:HGNC Symbol;Acc:HGNC:14064]",{"v":0.020941,"d":"0.02"},0,"inf","inf",1,1,"up","no"]
[175129,0,"chr7","-",75056517,75073881,"ENST00000618035",9,1409,"ENSG00000274523","RCC1L","GO:0003723(RNA binding);GO:0008150(biological_process);GO:0005575(cellular_component);GO:0005739(mitochondrion)","NA","NA","NA","RCC1 like [Source:HGNC Symbol;Acc:HGNC:14948]",{"v":0.285713,"d":"0.29"},{"v":0.279635,"d":"0.28"},{"v":1.02173547660343,"d":"1.02"},{"v":0.0310217364037149,"d":"0.03"},1,1,"up","no"]
[157248,0,"chr5","+",109804176,109820278,"ENST00000508043",4,546,"ENSG00000112893","MAN2A1","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0046872(metal ion binding);GO:0030246(carbohydrate binding);GO:0016787(hydrolase activity);GO:0003824(catalytic activity);GO:0005794(Golgi apparatus);GO:0005975(carbohydrate metabolic process);GO:0008152(metabolic process);GO:0016798(hydrolase activity, acting on glycosyl bonds);GO:0000139(Golgi membrane);GO:0006486(protein glycosylation);GO:0004559(alpha-mannosidase activity);GO:0006013(mannose metabolic process);GO:0070062(extracellular exosome);GO:0006517(protein deglycosylation);GO:0005797(Golgi medial cisterna);GO:0006491(N-glycan processing);GO:0004572(mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity);GO:0015923(mannosidase activity);GO:0016799(hydrolase activity, hydrolyzing N-glycosyl compounds);GO:0001701(in utero embryonic development);GO:0001889(liver development);GO:0007005(mitochondrion organization);GO:0007033(vacuole organization);GO:0007585(respiratory gaseous exchange);GO:0048286(lung alveolus development);GO:0050769(positive regulation of neurogenesis);GO:0060042(retina morphogenesis in camera-type eye);GO:0005615(extracellular space);GO:0005801(cis-Golgi network)","00510(N-Glycan biosynthesis)","NA","NA","mannosidase alpha class 2A member 1 [Source:HGNC Symbol;Acc:HGNC:6824]",{"v":0.092832,"d":"0.09"},{"v":0.485835,"d":"0.49"},{"v":0.191077217573868,"d":"0.19"},{"v":-2.38777232103342,"d":"-2.39"},1,1,"down","no"]
[153106,0,"chr5","+",892643,918120,"ENST00000166345",13,2672,"ENSG00000071539","TRIP13","GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0005515(protein binding);GO:1903506(regulation of nucleic acid-templated transcription);GO:0051321(meiotic cell cycle);GO:0030154(cell differentiation);GO:0007283(spermatogenesis);GO:0042802(identical protein binding);GO:0007130(synaptonemal complex assembly);GO:0007131(reciprocal meiotic recombination);GO:0048477(oogenesis);GO:0005634(nucleus);GO:0006366(transcription from RNA polymerase II promoter);GO:0003712(transcription cofactor activity);GO:0006302(double-strand break repair);GO:0001556(oocyte maturation);GO:0007141(male meiosis I);GO:0007144(female meiosis I);GO:0007286(spermatid development);GO:0001673(male germ cell nucleus)","NA","NA","NA","thyroid hormone receptor interactor 13 [Source:HGNC Symbol;Acc:HGNC:12307]",{"v":0.329663,"d":"0.33"},{"v":0.013091,"d":"0.01"},{"v":25.1824153998931,"d":"25.18"},{"v":4.65434476230979,"d":"4.65"},1,1,"up","no"]
[69550,0,"chr16","-",10627501,10694945,"ENST00000283025",7,1612,"ENSG00000153060","TEKT5","GO:0005634(nucleus);GO:0042995(cell projection);GO:0005515(protein binding);GO:0005929(cilium);GO:0060271(cilium assembly);GO:0030317(flagellated sperm motility);GO:0060294(cilium movement involved in cell motility);GO:0036126(sperm flagellum)","NA","NA","NA","tektin 5 [Source:HGNC Symbol;Acc:HGNC:26554]",{"v":0.192165,"d":"0.19"},0,"inf","inf",1,1,"up","no"]
[136234,0,"chr3","+",49198887,49258104,"ENST00000438782",8,2843,"ENSG00000173421","CCDC36","GO:0005694(chromosome);GO:0005515(protein binding);GO:0006310(DNA recombination);GO:0051321(meiotic cell cycle);GO:0030154(cell differentiation);GO:0007283(spermatogenesis);GO:0042138(meiotic DNA double-strand break formation);GO:0007129(synapsis);GO:0048477(oogenesis);GO:0000794(condensed nuclear chromosome);GO:0060629(regulation of homologous chromosome segregation)","NA","NA","NA","coiled-coil domain containing 36 [Source:HGNC Symbol;Acc:HGNC:27945]",{"v":0.031098,"d":"0.03"},0,"inf","inf",1,1,"up","no"]
[164103,0,"chr6","+",30647421,30653109,"ENST00000446773",6,1496,"MSTRG.12825","C6orf136","GO:0016020(membrane);GO:0016021(integral component of membrane)","NA","NA","NA","chromosome 6 open reading frame 136 [Source:HGNC Symbol;Acc:HGNC:21301]",{"v":0.212019,"d":"0.21"},{"v":0.157966,"d":"0.16"},{"v":1.34218122887204,"d":"1.34"},{"v":0.424579485504111,"d":"0.42"},1,1,"up","no"]
[45211,0,"chr12","+",93571361,93576206,"ENST00000549122",3,2391,"ENSG00000120833","SOCS2","GO:0005737(cytoplasm);GO:0016567(protein ubiquitination);GO:0035556(intracellular signal transduction);GO:0009967(positive regulation of signal transduction);GO:0005515(protein binding);GO:0001558(regulation of cell growth);GO:0005159(insulin-like growth factor receptor binding);GO:0008269(JAK pathway signal transduction adaptor activity);GO:0046426(negative regulation of JAK-STAT cascade);GO:0005829(cytosol);GO:0040008(regulation of growth);GO:0043687(post-translational protein modification);GO:0004860(protein kinase inhibitor activity);GO:0006469(negative regulation of protein kinase activity);GO:0019221(cytokine-mediated signaling pathway);GO:0043066(negative regulation of apoptotic process);GO:0005070(SH3/SH2 adaptor activity);GO:0005131(growth hormone receptor binding);GO:0007259(JAK-STAT cascade);GO:0009966(regulation of signal transduction);GO:0009968(negative regulation of signal transduction);GO:0032355(response to estradiol);GO:0032870(cellular response to hormone stimulus);GO:0046627(negative regulation of insulin receptor signaling pathway);GO:0060396(growth hormone receptor signaling pathway);GO:0007595(lactation);GO:0040014(regulation of multicellular organism growth);GO:0040015(negative regulation of multicellular organism growth);GO:0045666(positive regulation of neuron differentiation);GO:0060749(mammary gland alveolus development)","04630(Jak-STAT signaling pathway);04910(Insulin signaling pathway);04917(Prolactin signaling pathway);04930(Type II diabetes mellitus)","K04695","NA","suppressor of cytokine signaling 2 [Source:HGNC Symbol;Acc:HGNC:19382]",{"v":0.09385,"d":"0.09"},{"v":0.050157,"d":"0.05"},{"v":1.87112466854078,"d":"1.87"},{"v":0.903905685085181,"d":"0.90"},1,1,"up","no"]
[146557,0,"chr4","+",26857928,27002394,"ENST00000463501",6,1072,"ENSG00000109689","STIM2","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005246(calcium channel regulator activity);GO:0032237(activation of store-operated calcium channel activity);GO:0005886(plasma membrane);GO:0006810(transport);GO:0046872(metal ion binding);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0006811(ion transport);GO:0005515(protein binding);GO:0006816(calcium ion transport);GO:0070588(calcium ion transmembrane transport);GO:0005509(calcium ion binding);GO:0051928(positive regulation of calcium ion transport);GO:0006874(cellular calcium ion homeostasis);GO:0002115(store-operated calcium entry);GO:0015279(store-operated calcium channel activity)","04020(Calcium signaling pathway)","NA","NA","stromal interaction molecule 2 [Source:HGNC Symbol;Acc:HGNC:19205]",{"v":0.437008,"d":"0.44"},{"v":0.26599,"d":"0.27"},{"v":1.64294898304448,"d":"1.64"},{"v":0.716287682326046,"d":"0.72"},1,1,"up","no"]
[73923,0,"chr16","-",58716013,58734342,"ENST00000564400",7,983,"MSTRG.5974","GOT2","GO:0003723(RNA binding);GO:0006810(transport);GO:0016020(membrane);GO:0016740(transferase activity);GO:0003824(catalytic activity);GO:0009058(biosynthetic process);GO:0005739(mitochondrion);GO:0005886(plasma membrane);GO:0008483(transaminase activity);GO:0030170(pyridoxal phosphate binding);GO:0006869(lipid transport);GO:0005759(mitochondrial matrix);GO:0006520(cellular amino acid metabolic process);GO:0097052(L-kynurenine metabolic process);GO:0004069(L-aspartate:2-oxoglutarate aminotransferase activity);GO:0080130(L-phenylalanine:2-oxoglutarate aminotransferase activity);GO:0070062(extracellular exosome);GO:0006094(gluconeogenesis);GO:0019470(4-hydroxyproline catabolic process);GO:0006103(2-oxoglutarate metabolic process);GO:0008652(cellular amino acid biosynthetic process);GO:0045471(response to ethanol);GO:0005543(phospholipid binding);GO:0016212(kynurenine-oxoglutarate transaminase activity);GO:0016597(amino acid binding);GO:0019899(enzyme binding);GO:0031406(carboxylic acid binding);GO:0042803(protein homodimerization activity);GO:0047578(4-hydroxyglutamate transaminase activity);GO:0006107(oxaloacetate metabolic process);GO:0006531(aspartate metabolic process);GO:0006532(aspartate biosynthetic process);GO:0006533(aspartate catabolic process);GO:0006536(glutamate metabolic process);GO:0015908(fatty acid transport);GO:0019550(glutamate catabolic process to aspartate);GO:0019551(glutamate catabolic process to 2-oxoglutarate);GO:0043648(dicarboxylic acid metabolic process);GO:0046487(glyoxylate metabolic process);GO:0005743(mitochondrial inner membrane);GO:0009986(cell surface);GO:0043204(perikaryon);GO:0043209(myelin sheath);GO:0043234(protein complex)","00250(Alanine, aspartate and glutamate metabolism);00270(Cysteine and methionine metabolism);00220(Arginine biosynthesis);00330(Arginine and proline metabolism);00350(Tyrosine metabolism);00360(Phenylalanine metabolism);00400(Phenylalanine, tyrosine and tryptophan biosynthesis);04975(Fat digestion and absorption)","NA","NA","glutamic-oxaloacetic transaminase 2 [Source:HGNC Symbol;Acc:HGNC:4433]",0,0,1,0,1,1,"no","no"]
[12730,0,"chr1","-",161039295,161040583,"ENST00000472217",2,1097,"MSTRG.1130","USF1","GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0046983(protein dimerization activity);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0042802(identical protein binding);GO:0042803(protein homodimerization activity);GO:0046982(protein heterodimerization activity);GO:0005667(transcription factor complex);GO:0043425(bHLH transcription factor binding);GO:0000790(nuclear chromatin);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0003705(transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding);GO:0019899(enzyme binding);GO:0019901(protein kinase binding);GO:0048188(Set1C/COMPASS complex);GO:0042826(histone deacetylase binding);GO:0043565(sequence-specific DNA binding);GO:0032869(cellular response to insulin stimulus);GO:0006366(transcription from RNA polymerase II promoter);GO:0042593(glucose homeostasis);GO:0051918(negative regulation of fibrinolysis);GO:0055088(lipid homeostasis);GO:0001666(response to hypoxia);GO:0016589(NURF complex);GO:0000430(regulation of transcription from RNA polymerase II promoter by glucose);GO:0000432(positive regulation of transcription from RNA polymerase II promoter by glucose);GO:0009411(response to UV);GO:0019086(late viral transcription);GO:0045990(carbon catabolite regulation of transcription);GO:0003690(double-stranded DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0006006(glucose metabolic process);GO:0045893(positive regulation of transcription, DNA-templated)","NA","NA","NA","upstream transcription factor 1 [Source:HGNC Symbol;Acc:HGNC:12593]",0,0,1,0,1,1,"no","no"]
[135696,0,"chr3","-",47419385,47475937,"ENST00000416208",7,1222,"MSTRG.10889","SCAP","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005789(endoplasmic reticulum membrane);GO:0000139(Golgi membrane);GO:0008203(cholesterol metabolic process);GO:0015485(cholesterol binding);GO:0032933(SREBP signaling pathway);GO:0005794(Golgi apparatus);GO:0006629(lipid metabolic process);GO:0005783(endoplasmic reticulum);GO:0008202(steroid metabolic process);GO:0031410(cytoplasmic vesicle);GO:0005515(protein binding);GO:0045540(regulation of cholesterol biosynthetic process);GO:0051082(unfolded protein binding);GO:0012507(ER to Golgi transport vesicle membrane);GO:0045541(negative regulation of cholesterol biosynthetic process);GO:0032403(protein complex binding);GO:0001666(response to hypoxia);GO:0007568(aging);GO:0019217(regulation of fatty acid metabolic process);GO:0032868(response to insulin);GO:0042304(regulation of fatty acid biosynthetic process);GO:0045716(positive regulation of low-density lipoprotein particle receptor biosynthetic process);GO:0043231(intracellular membrane-bounded organelle);GO:0043234(protein complex)","NA","NA","NA","SREBF chaperone [Source:HGNC Symbol;Acc:HGNC:30634]",{"v":0.3739,"d":"0.37"},{"v":0.117627,"d":"0.12"},{"v":3.17869196698037,"d":"3.18"},{"v":1.66843321803567,"d":"1.67"},1,1,"up","no"]
[42988,0,"chr12","+",56224357,56226419,"ENST00000479016",4,1031,"MSTRG.3457","NABP2","GO:0003676(nucleic acid binding);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0006281(DNA repair);GO:0007093(mitotic cell cycle checkpoint);GO:0070876(SOSS complex);GO:0005634(nucleus);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0006974(cellular response to DNA damage stimulus);GO:0000784(nuclear chromosome, telomeric region);GO:0042795(snRNA transcription from RNA polymerase II promoter);GO:0000724(double-strand break repair via homologous recombination);GO:1904355(positive regulation of telomere capping);GO:0070200(establishment of protein localization to telomere);GO:0003697(single-stranded DNA binding);GO:0010212(response to ionizing radiation);GO:0070182(DNA polymerase binding);GO:0098505(G-rich strand telomeric DNA binding)","NA","NA","NA","nucleic acid binding protein 2 [Source:HGNC Symbol;Acc:HGNC:28412]",{"v":8.5e-05,"d":"0.00"},{"v":7.5e-05,"d":"0.00"},{"v":1.13333333333333,"d":"1.13"},{"v":0.180572245641821,"d":"0.18"},1,1,"up","no"]
[79287,0,"chr17","+",8435927,8446045,"ENST00000580738",3,552,"MSTRG.6431","NDEL1","GO:0007399(nervous system development);GO:0007100(mitotic centrosome separation);GO:0060052(neurofilament cytoskeleton organization);GO:2000574(regulation of microtubule motor activity);GO:0006810(transport);GO:0005737(cytoplasm);GO:0005694(chromosome);GO:1904115(axon cytoplasm);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0006508(proteolysis);GO:0007275(multicellular organism development);GO:0030154(cell differentiation);GO:0005874(microtubule);GO:0005815(microtubule organizing center);GO:0005819(spindle);GO:0042802(identical protein binding);GO:0007059(chromosome segregation);GO:0000775(chromosome, centromeric region);GO:0000776(kinetochore);GO:0000777(condensed chromosome kinetochore);GO:0005813(centrosome);GO:0005829(cytosol);GO:0008017(microtubule binding);GO:0007062(sister chromatid cohesion);GO:0005871(kinesin complex);GO:0016477(cell migration);GO:0033157(regulation of intracellular protein transport);GO:0047496(vesicle transport along microtubule);GO:0032403(protein complex binding);GO:0043014(alpha-tubulin binding);GO:0048487(beta-tubulin binding);GO:0070012(oligopeptidase activity);GO:0000132(establishment of mitotic spindle orientation);GO:0000226(microtubule cytoskeleton organization);GO:0001764(neuron migration);GO:0001833(inner cell mass cell proliferation);GO:0007020(microtubule nucleation);GO:0008090(retrograde axonal transport);GO:0008286(insulin receptor signaling pathway);GO:0010975(regulation of neuron projection development);GO:0021799(cerebral cortex radially oriented cell migration);GO:0021955(central nervous system neuron axonogenesis);GO:0031175(neuron projection development);GO:0043547(positive regulation of GTPase activity);GO:0045773(positive regulation of axon extension);GO:0048680(positive regulation of axon regeneration);GO:0051081(nuclear envelope disassembly);GO:0051303(establishment of chromosome localization);GO:0051642(centrosome localization);GO:0090630(activation of GTPase activity);GO:1990138(neuron projection extension);GO:0005635(nuclear envelope);GO:0005875(microtubule associated complex);GO:0008021(synaptic vesicle);GO:0030424(axon);GO:0031252(cell leading edge);GO:0043203(axon hillock);GO:0044297(cell body);GO:0060053(neurofilament cytoskeleton);GO:0090724(central region of growth cone)","NA","NA","NA","nudE neurodevelopment protein 1 like 1 [Source:HGNC Symbol;Acc:HGNC:17620]",0,{"v":0.148773,"d":"0.15"},"-inf","-inf",1,1,"down","no"]
[155730,0,"chr5","+",72816649,72883097,"ENST00000520850",9,863,"MSTRG.12114","TNPO1","GO:0003723(RNA binding);GO:0006810(transport);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0006886(intracellular protein transport);GO:0015031(protein transport);GO:0005515(protein binding);GO:0008536(Ran GTPase binding);GO:0035735(intraciliary transport involved in cilium assembly);GO:0005929(cilium);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0043488(regulation of mRNA stability);GO:0016032(viral process);GO:0008565(protein transporter activity);GO:0006607(NLS-bearing protein import into nucleus);GO:0031965(nuclear membrane);GO:0034399(nuclear periphery);GO:0008139(nuclear localization sequence binding);GO:0006610(ribosomal protein import into nucleus);GO:0000060(protein import into nucleus, translocation)","NA","NA","NA","transportin 1 [Source:HGNC Symbol;Acc:HGNC:6401]",0,0,1,0,1,1,"no","no"]
[11389,0,"chr1","+",154312462,154313084,"ENST00000612670",2,234,"ENSG00000278694","AL354980.1","NA","NA","NA","NA","NA",{"v":0.124478,"d":"0.12"},{"v":0.041919,"d":"0.04"},{"v":2.96948877597271,"d":"2.97"},{"v":1.57021457956059,"d":"1.57"},1,1,"up","no"]
[69141,0,"chr16","+",4624842,4688809,"ENST00000536343",15,1575,"MSTRG.5619","MGRN1","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0046872(metal ion binding);GO:0016740(transferase activity);GO:0016567(protein ubiquitination);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0005768(endosome);GO:0070062(extracellular exosome);GO:0008333(endosome to lysosome transport);GO:0005769(early endosome);GO:0004842(ubiquitin-protein transferase activity);GO:0006513(protein monoubiquitination);GO:0061630(ubiquitin protein ligase activity);GO:0000209(protein polyubiquitination);GO:0043951(negative regulation of cAMP-mediated signaling);GO:0045744(negative regulation of G-protein coupled receptor protein signaling pathway);GO:0016874(ligase activity)","04120(Ubiquitin mediated proteolysis)","K10604","EC:2.3.2.27","mahogunin ring finger 1 [Source:HGNC Symbol;Acc:HGNC:20254]",0,0,1,0,1,1,"no","no"]
[192088,0,"chr9","-",97198303,97199511,"ENST00000568013",1,1209,"ENSG00000188801","ZNF322P1","NA","NA","NA","NA","zinc finger protein 322 pseudogene 1 [Source:HGNC Symbol;Acc:HGNC:14003]",0,{"v":1.364062,"d":"1.36"},"-inf","-inf",1,1,"down","no"]
[12586,0,"chr1","-",160217467,160262531,"ENST00000461888",14,2277,"MSTRG.1111","DCAF8","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0005739(mitochondrion);GO:0016567(protein ubiquitination);GO:0005515(protein binding);GO:0043687(post-translational protein modification);GO:0080008(Cul4-RING E3 ubiquitin ligase complex)","NA","NA","NA","DDB1 and CUL4 associated factor 8 [Source:HGNC Symbol;Acc:HGNC:24891]",{"v":0.790614,"d":"0.79"},{"v":0.097987,"d":"0.10"},{"v":8.06856011511731,"d":"8.07"},{"v":3.01231123854351,"d":"3.01"},1,1,"up","no"]
[180262,0,"chr7","+",151139568,151144432,"ENST00000473633",5,3751,"ENSG00000133612","AGAP3","GO:0005737(cytoplasm);GO:0005525(GTP binding);GO:0016020(membrane);GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0007165(signal transduction);GO:0003924(GTPase activity);GO:0043547(positive regulation of GTPase activity);GO:0005096(GTPase activator activity)","04144(Endocytosis)","NA","NA","ArfGAP with GTPase domain, ankyrin repeat and PH domain 3 [Source:HGNC Symbol;Acc:HGNC:16923]",{"v":0.082437,"d":"0.08"},{"v":0.621878,"d":"0.62"},{"v":0.132561370558212,"d":"0.13"},{"v":-2.91526767104672,"d":"-2.92"},1,1,"down","no"]
[142450,0,"chr3","+",167822936,167825560,"ENST00000494666",3,541,"ENSG00000163536","SERPINI1","GO:0005615(extracellular space);GO:0010951(negative regulation of endopeptidase activity);GO:0005576(extracellular region);GO:0031410(cytoplasmic vesicle);GO:0030414(peptidase inhibitor activity);GO:0010466(negative regulation of peptidase activity);GO:0043204(perikaryon);GO:0070062(extracellular exosome);GO:0004867(serine-type endopeptidase inhibitor activity);GO:0007417(central nervous system development);GO:0007422(peripheral nervous system development);GO:0043025(neuronal cell body);GO:0060205(cytoplasmic vesicle lumen);GO:0010976(positive regulation of neuron projection development);GO:0030155(regulation of cell adhesion);GO:0034774(secretory granule lumen)","NA","NA","NA","serpin family I member 1 [Source:HGNC Symbol;Acc:HGNC:8943]",0,{"v":0.060719,"d":"0.06"},"-inf","-inf",1,1,"down","no"]
[102642,0,"chr19","+",44954591,44993190,"ENST00000546079",14,2342,"MSTRG.8218","CLPTM1","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005515(protein binding);GO:0007275(multicellular organism development);GO:0030154(cell differentiation);GO:0005887(integral component of plasma membrane);GO:0009897(external side of plasma membrane);GO:0033081(regulation of T cell differentiation in thymus)","NA","NA","NA","CLPTM1, transmembrane protein [Source:HGNC Symbol;Acc:HGNC:2087]",0,0,1,0,1,1,"no","no"]
[26034,0,"chr11","-",6401347,6404796,"ENST00000533139",9,1147,"MSTRG.2200","APBB1","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016607(nuclear speck);GO:0016020(membrane);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0016569(covalent chromatin modification);GO:0005886(plasma membrane);GO:0042995(cell projection);GO:0005515(protein binding);GO:0007165(signal transduction);GO:0006974(cellular response to DNA damage stimulus);GO:0006915(apoptotic process);GO:0045202(synapse);GO:0045893(positive regulation of transcription, DNA-templated);GO:0005654(nucleoplasm);GO:0008134(transcription factor binding);GO:0007409(axonogenesis);GO:0030027(lamellipodium);GO:0030426(growth cone);GO:0001540(amyloid-beta binding);GO:0003682(chromatin binding);GO:0007050(cell cycle arrest);GO:0043065(positive regulation of apoptotic process);GO:0042393(histone binding);GO:0070064(proline-rich region binding);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0030308(negative regulation of cell growth);GO:0043967(histone H4 acetylation);GO:0050760(negative regulation of thymidylate synthase biosynthetic process);GO:0032403(protein complex binding);GO:0048156(tau protein binding);GO:0006302(double-strand break repair);GO:0010039(response to iron ion);GO:0010976(positive regulation of neuron projection development);GO:0045739(positive regulation of DNA repair);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0050714(positive regulation of protein secretion);GO:0042734(presynaptic membrane);GO:0043025(neuronal cell body);GO:0043197(dendritic spine);GO:0043234(protein complex);GO:0044304(main axon);GO:0045211(postsynaptic membrane);GO:0048471(perinuclear region of cytoplasm);GO:1990761(growth cone lamellipodium);GO:1990812(growth cone filopodium)","05010(Alzheimer's disease)","NA","NA","amyloid beta precursor protein binding family B member 1 [Source:HGNC Symbol;Acc:HGNC:581]",0,0,1,0,1,1,"no","no"]
[68736,0,"chr16","+",3112579,3120515,"ENST00000620094",7,2309,"ENSG00000122386","ZNF205","GO:0005739(mitochondrion);GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0005622(intracellular);GO:0008270(zinc ion binding);GO:0005515(protein binding);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0010729(positive regulation of hydrogen peroxide biosynthetic process);GO:1901030(positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway);GO:0000977(RNA polymerase II regulatory region sequence-specific DNA binding);GO:0001227(transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding)","NA","NA","NA","zinc finger protein 205 [Source:HGNC Symbol;Acc:HGNC:12996]",{"v":0.207677,"d":"0.21"},{"v":0.246906,"d":"0.25"},{"v":0.84111767231254,"d":"0.84"},{"v":-0.249620447336642,"d":"-0.25"},1,1,"down","no"]
[77183,0,"chr16","+",89972648,89984699,"ENST00000421164",6,1706,"ENSG00000223959","AFG3L1P","NA","NA","NA","NA","AFG3 like matrix AAA peptidase subunit 1, pseudogene [Source:HGNC Symbol;Acc:HGNC:314]",{"v":0.1794,"d":"0.18"},{"v":0.084305,"d":"0.08"},{"v":2.12798766383963,"d":"2.13"},{"v":1.08948978741383,"d":"1.09"},1,1,"up","no"]
[119376,0,"chr2","+",219229885,219232013,"ENST00000416565",2,552,"MSTRG.9448","ANKZF1","GO:0003676(nucleic acid binding);GO:0016020(membrane);GO:0046872(metal ion binding);GO:0005515(protein binding);GO:0030433(ubiquitin-dependent ERAD pathway);GO:0004843(thiol-dependent ubiquitin-specific protease activity);GO:0071630(ubiquitin-dependent catabolism of misfolded proteins by nucleus-associated proteasome);GO:0072671(mitochondria-associated ubiquitin-dependent protein catabolic process);GO:0036266(Cdc48p-Npl4p-Vms1p AAA ATPase complex)","NA","NA","NA","ankyrin repeat and zinc finger domain containing 1 [Source:HGNC Symbol;Acc:HGNC:25527]",{"v":0.010989,"d":"0.01"},{"v":0.00368,"d":"0.00"},{"v":2.98614130434783,"d":"2.99"},{"v":1.57828243548534,"d":"1.58"},1,1,"up","no"]
[121812,0,"chr20","+",5176102,5191354,"ENST00000379070",10,2713,"MSTRG.9588","CDS2","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016740(transferase activity);GO:0005743(mitochondrial inner membrane);GO:0016772(transferase activity, transferring phosphorus-containing groups);GO:0006629(lipid metabolic process);GO:0005739(mitochondrion);GO:0008654(phospholipid biosynthetic process);GO:0016779(nucleotidyltransferase activity);GO:0004605(phosphatidate cytidylyltransferase activity);GO:0016024(CDP-diacylglycerol biosynthetic process);GO:0005789(endoplasmic reticulum membrane);GO:0006655(phosphatidylglycerol biosynthetic process);GO:0005783(endoplasmic reticulum)","00564(Glycerophospholipid metabolism);04070(Phosphatidylinositol signaling system)","NA","NA","CDP-diacylglycerol synthase 2 [Source:HGNC Symbol;Acc:HGNC:1801]",{"v":0.103527,"d":"0.10"},{"v":0.144426,"d":"0.14"},{"v":0.716816916621661,"d":"0.72"},{"v":-0.480323410005523,"d":"-0.48"},1,1,"down","no"]
[91918,0,"chr18","+",37067340,37084425,"ENST00000599493",2,507,"MSTRG.7499","KIAA1328","GO:0005515(protein binding)","NA","NA","NA","KIAA1328 [Source:HGNC Symbol;Acc:HGNC:29248]",0,0,1,0,1,1,"no","no"]
[95917,0,"chr19","-",8322584,8343262,"ENST00000330915",11,2787,"MSTRG.7762","KANK3","NA","NA","NA","NA","KN motif and ankyrin repeat domains 3 [Source:HGNC Symbol;Acc:HGNC:24796]",{"v":0.313015,"d":"0.31"},{"v":0.078889,"d":"0.08"},{"v":3.96779018621101,"d":"3.97"},{"v":1.98833573910282,"d":"1.99"},1,1,"up","no"]
[69732,0,"chr16","+",11908208,11908916,"ENST00000562802",2,384,"MSTRG.5658","AC007216.2","NA","NA","NA","NA","NA",0,0,1,0,1,1,"no","no"]
[17947,0,"chr10","+",134484,254626,"ENST00000309776",14,4228,"ENSG00000015171","ZMYND11","GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0005654(nucleoplasm);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0016569(covalent chromatin modification);GO:0003677(DNA binding);GO:0005694(chromosome);GO:0008270(zinc ion binding);GO:0005515(protein binding);GO:0007049(cell cycle);GO:0003682(chromatin binding);GO:1903507(negative regulation of nucleic acid-templated transcription);GO:0051607(defense response to virus);GO:0003714(transcription corepressor activity);GO:0000977(RNA polymerase II regulatory region sequence-specific DNA binding);GO:0016032(viral process);GO:0003690(double-stranded DNA binding);GO:0046329(negative regulation of JNK cascade);GO:0008283(cell proliferation);GO:0035064(methylated histone binding);GO:0043124(negative regulation of I-kappaB kinase/NF-kappaB signaling);GO:0042393(histone binding);GO:2001237(negative regulation of extrinsic apoptotic signaling pathway);GO:0003712(transcription cofactor activity);GO:0034243(regulation of transcription elongation from RNA polymerase II promoter);GO:0016020(membrane);GO:0016021(integral component of membrane)","NA","NA","NA","zinc finger MYND-type containing 11 [Source:HGNC Symbol;Acc:HGNC:16966]",0,{"v":0.03832,"d":"0.04"},"-inf","-inf",1,1,"down","no"]
[20913,0,"chr10","+",69258871,69261637,"ENST00000470920",2,588,"ENSG00000156510","HKDC1","GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0005739(mitochondrion);GO:0006096(glycolytic process);GO:0004396(hexokinase activity);GO:0005536(glucose binding);GO:0016773(phosphotransferase activity, alcohol group as acceptor);GO:0001678(cellular glucose homeostasis);GO:0005975(carbohydrate metabolic process);GO:0046835(carbohydrate phosphorylation);GO:0051156(glucose 6-phosphate metabolic process);GO:0005829(cytosol);GO:0004340(glucokinase activity);GO:0008865(fructokinase activity);GO:0019158(mannokinase activity);GO:0019318(hexose metabolic process)","00010(Glycolysis / Gluconeogenesis);00051(Fructose and mannose metabolism);00052(Galactose metabolism);00500(Starch and sucrose metabolism);00520(Amino sugar and nucleotide sugar metabolism);00524(Neomycin, kanamycin and gentamicin biosynthesis);04066(HIF-1 signaling pathway);04910(Insulin signaling pathway);04973(Carbohydrate digestion and absorption);05230(Central carbon metabolism in cancer);04930(Type II diabetes mellitus)","NA","NA","hexokinase domain containing 1 [Source:HGNC Symbol;Acc:HGNC:23302]",0,{"v":0.112746,"d":"0.11"},"-inf","-inf",1,1,"down","no"]
[75921,0,"chr16","+",78099654,79212667,"ENST00000406884",6,1701,"ENSG00000186153","WWOX","GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005794(Golgi apparatus);GO:0005829(cytosol);GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0005739(mitochondrion);GO:0008202(steroid metabolic process);GO:0005515(protein binding);GO:0048037(cofactor binding);GO:0006915(apoptotic process);GO:0016055(Wnt signaling pathway);GO:0030178(negative regulation of Wnt signaling pathway);GO:0005886(plasma membrane);GO:0090575(RNA polymerase II transcription factor complex);GO:0019899(enzyme binding);GO:0071560(cellular response to transforming growth factor beta stimulus);GO:0046983(protein dimerization activity);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:2001238(positive regulation of extrinsic apoptotic signaling pathway);GO:0005902(microvillus);GO:0050662(coenzyme binding);GO:0001105(RNA polymerase II transcription coactivator activity);GO:0048705(skeletal system morphogenesis);GO:0001649(osteoblast differentiation);GO:0072332(intrinsic apoptotic signaling pathway by p53 class mediator);GO:0097191(extrinsic apoptotic signaling pathway);GO:2001241(positive regulation of extrinsic apoptotic signaling pathway in absence of ligand)","NA","NA","NA","WW domain containing oxidoreductase [Source:HGNC Symbol;Acc:HGNC:12799]",{"v":0.004298,"d":"0.00"},0,"inf","inf",1,1,"up","no"]
[41076,0,"chr12","-",48857147,48859282,"ENST00000548445",1,2136,"ENSG00000172602","RND1","GO:0043231(intracellular membrane-bounded organelle);GO:0005525(GTP binding);GO:0003924(GTPase activity);GO:0005886(plasma membrane);GO:0015629(actin cytoskeleton);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0007264(small GTPase mediated signal transduction);GO:0000166(nucleotide binding);GO:0005622(intracellular);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0005829(cytosol);GO:0005912(adherens junction);GO:0005102(receptor binding);GO:0007162(negative regulation of cell adhesion);GO:0007015(actin filament organization);GO:0016322(neuron remodeling)","04360(Axon guidance)","NA","NA","Rho family GTPase 1 [Source:HGNC Symbol;Acc:HGNC:18314]",{"v":0.024065,"d":"0.02"},0,"inf","inf",1,1,"up","no"]
[17178,0,"chr1","+",235328571,235343138,"ENST00000391855",3,1407,"MSTRG.1480","GGPS1","GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0016740(transferase activity);GO:0008299(isoprenoid biosynthetic process);GO:0005515(protein binding);GO:0042802(identical protein binding);GO:0005829(cytosol);GO:0045540(regulation of cholesterol biosynthetic process);GO:0006720(isoprenoid metabolic process);GO:0006695(cholesterol biosynthetic process);GO:0004161(dimethylallyltranstransferase activity);GO:0004311(farnesyltranstransferase activity);GO:0004337(geranyltranstransferase activity);GO:0033384(geranyl diphosphate biosynthetic process);GO:0033386(geranylgeranyl diphosphate biosynthetic process);GO:0045337(farnesyl diphosphate biosynthetic process)","00900(Terpenoid backbone biosynthesis)","NA","NA","geranylgeranyl diphosphate synthase 1 [Source:HGNC Symbol;Acc:HGNC:4249]",0,0,1,0,1,1,"no","no"]
[19336,0,"chr10","+",28533749,28595777,"ENST00000442148",7,759,"MSTRG.1633","WAC","GO:0005634(nucleus);GO:0016607(nuclear speck);GO:0005654(nucleoplasm);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0016569(covalent chromatin modification);GO:0005515(protein binding);GO:0006974(cellular response to DNA damage stimulus);GO:0045893(positive regulation of transcription, DNA-templated);GO:0016567(protein ubiquitination);GO:0003682(chromatin binding);GO:0016239(positive regulation of macroautophagy);GO:0032435(negative regulation of proteasomal ubiquitin-dependent protein catabolic process);GO:0010390(histone monoubiquitination);GO:0000993(RNA polymerase II core binding);GO:0044783(G1 DNA damage checkpoint);GO:0071894(histone H2B conserved C-terminal lysine ubiquitination);GO:0005681(spliceosomal complex)","NA","NA","NA","WW domain containing adaptor with coiled-coil [Source:HGNC Symbol;Acc:HGNC:17327]",{"v":0.552548,"d":"0.55"},{"v":0.18164,"d":"0.18"},{"v":3.04199515525215,"d":"3.04"},{"v":1.60501785539664,"d":"1.61"},1,1,"up","no"]
[160115,0,"chr5","+",150848497,150900736,"ENST00000520549",4,503,"ENSG00000237693","IRGM","GO:0016020(membrane);GO:0005525(GTP binding);GO:0000166(nucleotide binding);GO:0016787(hydrolase activity);GO:0005794(Golgi apparatus);GO:0005829(cytosol);GO:0005739(mitochondrion);GO:0005886(plasma membrane);GO:0042995(cell projection);GO:0000139(Golgi membrane);GO:0006914(autophagy);GO:0031410(cytoplasmic vesicle);GO:0002376(immune system process);GO:0045087(innate immune response);GO:0006954(inflammatory response);GO:0042742(defense response to bacterium);GO:0005515(protein binding);GO:0019901(protein kinase binding);GO:0043539(protein serine/threonine kinase activator activity);GO:0050700(CARD domain binding);GO:0051434(BH3 domain binding);GO:0000045(autophagosome assembly);GO:0001934(positive regulation of protein phosphorylation);GO:0010508(positive regulation of autophagy);GO:0010800(positive regulation of peptidyl-threonine phosphorylation);GO:0031648(protein destabilization);GO:0033138(positive regulation of peptidyl-serine phosphorylation);GO:0043254(regulation of protein complex assembly);GO:0050821(protein stabilization);GO:0050829(defense response to Gram-negative bacterium);GO:0060335(positive regulation of interferon-gamma-mediated signaling pathway);GO:0061635(regulation of protein complex stability);GO:0061739(protein lipidation involved in autophagosome assembly);GO:0061762(CAMKK-AMPK signaling cascade);GO:0070431(nucleotide-binding oligomerization domain containing 2 signaling pathway);GO:0071222(cellular response to lipopolysaccharide);GO:0071902(positive regulation of protein serine/threonine kinase activity);GO:0075044(autophagy of host cells involved in interaction with symbiont);GO:0098586(cellular response to virus);GO:1901098(positive regulation of autophagosome maturation);GO:0000421(autophagosome membrane);GO:0001891(phagocytic cup);GO:0030670(phagocytic vesicle membrane)","05145(Toxoplasmosis)","NA","NA","immunity related GTPase M [Source:HGNC Symbol;Acc:HGNC:29597]",0,0,1,0,1,1,"no","no"]
[123815,0,"chr20","-",41997131,41999397,"ENST00000432563",1,2267,"ENSG00000223651","AL049812.1","NA","NA","NA","NA","NA",{"v":0.022674,"d":"0.02"},0,"inf","inf",1,1,"up","no"]
[141304,0,"chr3","+",142689630,142698438,"ENST00000483507",3,749,"ENSG00000120756","PLS1","GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0003779(actin binding);GO:0005509(calcium ion binding);GO:0051015(actin filament binding);GO:0070062(extracellular exosome);GO:0051017(actin filament bundle assembly);GO:0005903(brush border);GO:0005200(structural constituent of cytoskeleton);GO:0090004(positive regulation of establishment of protein localization to plasma membrane);GO:0051639(actin filament network formation);GO:0005884(actin filament);GO:0051764(actin crosslink formation);GO:0032432(actin filament bundle);GO:0001951(intestinal D-glucose absorption);GO:0032532(regulation of microvillus length);GO:0040018(positive regulation of multicellular organism growth);GO:1902896(terminal web assembly);GO:1990357(terminal web)","NA","NA","NA","plastin 1 [Source:HGNC Symbol;Acc:HGNC:9090]",0,{"v":0.023018,"d":"0.02"},"-inf","-inf",1,1,"down","no"]
[24203,0,"chr10","-",125038997,125161170,"ENST00000476817",3,705,"MSTRG.2035","CTBP2","GO:0005634(nucleus);GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0008152(metabolic process);GO:0016616(oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor);GO:0005515(protein binding);GO:0051287(NAD binding);GO:0030054(cell junction);GO:0045202(synapse);GO:0030154(cell differentiation);GO:0005829(cytosol);GO:0003714(transcription corepressor activity);GO:0016032(viral process);GO:0045892(negative regulation of transcription, DNA-templated);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0019079(viral genome replication);GO:0008285(negative regulation of cell proliferation);GO:0042803(protein homodimerization activity);GO:0050872(white fat cell differentiation);GO:0017053(transcriptional repressor complex);GO:0019901(protein kinase binding);GO:0032403(protein complex binding);GO:0016618(hydroxypyruvate reductase activity);GO:0030267(glyoxylate reductase (NADP) activity);GO:0048386(positive regulation of retinoic acid receptor signaling pathway);GO:0003682(chromatin binding);GO:0003713(transcription coactivator activity);GO:0042974(retinoic acid receptor binding);GO:0035563(positive regulation of chromatin binding);GO:1990830(cellular response to leukemia inhibitory factor);GO:0097470(ribbon synapse)","04310(Wnt signaling pathway);04330(Notch signaling pathway);05200(Pathways in cancer);05220(Chronic myeloid leukemia)","NA","NA","C-terminal binding protein 2 [Source:HGNC Symbol;Acc:HGNC:2495]",0,0,1,0,1,1,"no","no"]
[163029,0,"chr6","-",15523985,15662920,"ENST00000506844",10,1542,"MSTRG.12689","DTNBP1","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:1904115(axon cytoplasm);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005886(plasma membrane);GO:0015630(microtubule cytoskeleton);GO:0005515(protein binding);GO:0030496(midbody);GO:0030054(cell junction);GO:0045202(synapse);GO:0045211(postsynaptic membrane);GO:0030659(cytoplasmic vesicle membrane);GO:0031410(cytoplasmic vesicle);GO:0050896(response to stimulus);GO:0001956(positive regulation of neurotransmitter secretion);GO:0006996(organelle organization);GO:0007596(blood coagulation);GO:0008089(anterograde axonal transport);GO:0010628(positive regulation of gene expression);GO:0014059(regulation of dopamine secretion);GO:0031532(actin cytoskeleton reorganization);GO:0032091(negative regulation of protein binding);GO:0043506(regulation of JUN kinase activity);GO:0048490(anterograde synaptic vesicle transport);GO:0048812(neuron projection morphogenesis);GO:0048813(dendrite morphogenesis);GO:0060155(platelet dense granule organization);GO:0071901(negative regulation of protein serine/threonine kinase activity);GO:0014069(postsynaptic density);GO:0016528(sarcoplasm);GO:0030424(axon);GO:0030426(growth cone);GO:0030672(synaptic vesicle membrane);GO:0031083(BLOC-1 complex);GO:0042383(sarcolemma);GO:0043197(dendritic spine);GO:0005768(endosome);GO:0005829(cytosol);GO:0010008(endosome membrane);GO:0043005(neuron projection);GO:0032438(melanosome organization);GO:0031175(neuron projection development);GO:0033162(melanosome membrane);GO:0060159(regulation of dopamine receptor signaling pathway)","NA","NA","NA","dystrobrevin binding protein 1 [Source:HGNC Symbol;Acc:HGNC:17328]",0,{"v":0.145504,"d":"0.15"},"-inf","-inf",1,1,"down","no"]
[131640,0,"chr22","+",40857077,40870343,"ENST00000417688",3,582,"MSTRG.10488","XPNPEP3","GO:0046872(metal ion binding);GO:0016787(hydrolase activity);GO:0005739(mitochondrion);GO:0008233(peptidase activity);GO:0006508(proteolysis);GO:0030145(manganese ion binding);GO:0008237(metallopeptidase activity);GO:0004177(aminopeptidase activity);GO:0070062(extracellular exosome);GO:0016485(protein processing);GO:0003094(glomerular filtration)","NA","NA","NA","X-prolyl aminopeptidase 3 [Source:HGNC Symbol;Acc:HGNC:28052]",0,{"v":0.003121,"d":"0.00"},"-inf","-inf",1,1,"down","no"]
[60615,0,"chr15","+",32593456,32594840,"ENST00000453952",1,1385,"ENSG00000232653","GOLGA8N","GO:0005794(Golgi apparatus)","NA","NA","NA","golgin A8 family member N [Source:HGNC Symbol;Acc:HGNC:44405]",{"v":0.108,"d":"0.11"},{"v":0.032941,"d":"0.03"},{"v":3.27858899244103,"d":"3.28"},{"v":1.71307505521298,"d":"1.71"},1,1,"up","no"]
[50296,0,"chr13","+",48976673,49209607,"ENST00000484074",26,6082,"ENSG00000102531","FNDC3A","GO:0003723(RNA binding);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005794(Golgi apparatus);GO:0000139(Golgi membrane);GO:0007286(spermatid development);GO:0009566(fertilization);GO:0016337(single organismal cell-cell adhesion);GO:0060009(Sertoli cell development);GO:0001669(acrosomal vesicle);GO:0005829(cytosol);GO:0012506(vesicle membrane);GO:0031410(cytoplasmic vesicle)","NA","NA","NA","fibronectin type III domain containing 3A [Source:HGNC Symbol;Acc:HGNC:20296]",0,{"v":0.090347,"d":"0.09"},"-inf","-inf",1,1,"down","no"]
[102759,0,"chr19","-",45409546,45414616,"ENST00000588738",4,586,"ENSG00000012061","ERCC1","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0016787(hydrolase activity);GO:0003677(DNA binding);GO:0003684(damaged DNA binding);GO:0004519(endonuclease activity);GO:0006281(DNA repair);GO:0090305(nucleic acid phosphodiester bond hydrolysis);GO:0005515(protein binding);GO:0006974(cellular response to DNA damage stimulus);GO:0004518(nuclease activity);GO:0036297(interstrand cross-link repair);GO:0008022(protein C-terminus binding);GO:0019904(protein domain specific binding);GO:0006979(response to oxidative stress);GO:0003697(single-stranded DNA binding);GO:0006283(transcription-coupled nucleotide-excision repair);GO:0090656(t-circle formation);GO:0000014(single-stranded DNA endodeoxyribonuclease activity);GO:1990599(3' overhang single-stranded DNA endodeoxyribonuclease activity);GO:0000710(meiotic mismatch repair);GO:0006289(nucleotide-excision repair);GO:0006293(nucleotide-excision repair, preincision complex stabilization);GO:0006295(nucleotide-excision repair, DNA incision, 3'-to lesion);GO:0006296(nucleotide-excision repair, DNA incision, 5'-to lesion);GO:0006303(double-strand break repair via nonhomologous end joining);GO:0006310(DNA recombination);GO:0006312(mitotic recombination);GO:0032205(negative regulation of telomere maintenance);GO:0033683(nucleotide-excision repair, DNA incision);GO:0061819(telomeric DNA-containing double minutes formation);GO:0070911(global genome nucleotide-excision repair);GO:0070914(UV-damage excision repair);GO:1904431(positive regulation of t-circle formation);GO:1905765(negative regulation of protection from non-homologous end joining at telomere);GO:0000109(nucleotide-excision repair complex);GO:0000110(nucleotide-excision repair factor 1 complex);GO:0000784(nuclear chromosome, telomeric region);GO:0070522(ERCC4-ERCC1 complex);GO:0001094(TFIID-class transcription factor binding);GO:0000720(pyrimidine dimer repair by nucleotide-excision repair);GO:0001302(replicative cell aging);GO:0006302(double-strand break repair);GO:0006949(syncytium formation);GO:0007281(germ cell development);GO:0007283(spermatogenesis);GO:0007584(response to nutrient);GO:0008283(cell proliferation);GO:0008584(male gonad development);GO:0009650(UV protection);GO:0009744(response to sucrose);GO:0010165(response to X-ray);GO:0010259(multicellular organism aging);GO:0035166(post-embryonic hemopoiesis);GO:0035264(multicellular organism growth);GO:0045190(isotype switching);GO:0048468(cell development);GO:0048477(oogenesis);GO:0048568(embryonic organ development);GO:0051276(chromosome organization);GO:0005669(transcription factor TFIID complex)","03420(Nucleotide excision repair);03460(Fanconi anemia pathway);01524(Platinum drug resistance)","NA","NA","ERCC excision repair 1, endonuclease non-catalytic subunit [Source:HGNC Symbol;Acc:HGNC:3433]",{"v":0.05811,"d":"0.06"},{"v":0.034007,"d":"0.03"},{"v":1.70876584232658,"d":"1.71"},{"v":0.772954713421704,"d":"0.77"},1,1,"up","no"]
[18588,0,"chr10","-",13318080,13348280,"ENST00000378614",8,2387,"ENSG00000086475","SEPHS1","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0042802(identical protein binding);GO:0031965(nuclear membrane);GO:0005525(GTP binding);GO:0006464(cellular protein modification process);GO:0004756(selenide, water dikinase activity);GO:0016260(selenocysteine biosynthetic process)","00450(Selenocompound metabolism)","K01008","EC:2.7.9.3","selenophosphate synthetase 1 [Source:HGNC Symbol;Acc:HGNC:19685]",0,{"v":0.830888,"d":"0.83"},"-inf","-inf",1,1,"down","no"]
[14838,0,"chr1","+",201962216,201970351,"ENST00000482943",3,2523,"MSTRG.1292","TIMM17A","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0006886(intracellular protein transport);GO:0015031(protein transport);GO:0005654(nucleoplasm);GO:0015450(P-P-bond-hydrolysis-driven protein transmembrane transporter activity);GO:0005739(mitochondrion);GO:0005743(mitochondrial inner membrane);GO:0005744(mitochondrial inner membrane presequence translocase complex);GO:0015266(protein channel activity);GO:0006626(protein targeting to mitochondrion);GO:0030150(protein import into mitochondrial matrix);GO:0031305(integral component of mitochondrial inner membrane)","NA","NA","NA","translocase of inner mitochondrial membrane 17A [Source:HGNC Symbol;Acc:HGNC:17315]",{"v":0.087187,"d":"0.09"},{"v":0.027777,"d":"0.03"},{"v":3.13881988695683,"d":"3.14"},{"v":1.6502222459798,"d":"1.65"},1,1,"up","no"]
[29920,0,"chr11","-",61349841,61361849,"ENST00000544118",5,1136,"MSTRG.2442","CYB561A3","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0046872(metal ion binding);GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0005765(lysosomal membrane);GO:0005515(protein binding);GO:0005764(lysosome);GO:0005768(endosome);GO:0031902(late endosome membrane)","NA","NA","NA","cytochrome b561 family member A3 [Source:HGNC Symbol;Acc:HGNC:23014]",0,{"v":0.108118,"d":"0.11"},"-inf","-inf",1,1,"down","no"]
[1832,0,"chr1","+",15324469,15330008,"ENST00000459961",2,4406,"ENSG00000142621","FHAD1","NA","NA","NA","NA","forkhead associated phosphopeptide binding domain 1 [Source:HGNC Symbol;Acc:HGNC:29408]",0,{"v":0.02071,"d":"0.02"},"-inf","-inf",1,1,"down","no"]
[31189,0,"chr11","-",65379458,65380989,"ENST00000525944",4,676,"ENSG00000162241","SLC25A45","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0055085(transmembrane transport);GO:0005743(mitochondrial inner membrane);GO:0005739(mitochondrion);GO:0006839(mitochondrial transport);GO:0022857(transmembrane transporter activity)","NA","NA","NA","solute carrier family 25 member 45 [Source:HGNC Symbol;Acc:HGNC:27442]",{"v":0.100304,"d":"0.10"},{"v":0.041658,"d":"0.04"},{"v":2.40779682173892,"d":"2.41"},{"v":1.26771365761392,"d":"1.27"},1,1,"up","no"]
[44155,0,"chr12","+",68610918,68657150,"ENST00000538980",6,587,"MSTRG.3540","RAP1B","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005525(GTP binding);GO:0000166(nucleotide binding);GO:0007165(signal transduction);GO:0003924(GTPase activity);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0030054(cell junction);GO:0007264(small GTPase mediated signal transduction);GO:0008283(cell proliferation);GO:0009743(response to carbohydrate);GO:0035690(cellular response to drug);GO:0045955(negative regulation of calcium ion-dependent exocytosis);GO:0070374(positive regulation of ERK1 and ERK2 cascade);GO:0071407(cellular response to organic cyclic compound);GO:0097211(cellular response to gonadotropin-releasing hormone);GO:2000301(negative regulation of synaptic vesicle exocytosis);GO:2000114(regulation of establishment of cell polarity);GO:0070062(extracellular exosome);GO:0043312(neutrophil degranulation);GO:0035722(interleukin-12-mediated signaling pathway);GO:0019003(GDP binding);GO:0032403(protein complex binding);GO:0061028(establishment of endothelial barrier);GO:0035577(azurophil granule membrane);GO:0005911(cell-cell junction);GO:0005811(lipid particle);GO:0005622(intracellular);GO:0071320(cellular response to cAMP);GO:0032486(Rap protein signal transduction);GO:1901888(regulation of cell junction assembly)","04014(Ras signaling pathway);04015(Rap1 signaling pathway);04010(MAPK signaling pathway);04024(cAMP signaling pathway);04510(Focal adhesion);04611(Platelet activation);04670(Leukocyte transendothelial migration);04062(Chemokine signaling pathway);04972(Pancreatic secretion);04720(Long-term potentiation);04722(Neurotrophin signaling pathway);05211(Renal cell carcinoma)","NA","NA","RAP1B, member of RAS oncogene family [Source:HGNC Symbol;Acc:HGNC:9857]",{"v":0.161599,"d":"0.16"},{"v":0.348925,"d":"0.35"},{"v":0.46313391129899,"d":"0.46"},{"v":-1.11049869787229,"d":"-1.11"},1,1,"down","no"]
[154423,0,"chr5","+",40681702,40692043,"ENST00000513635",3,537,"MSTRG.12017","PTGER4","GO:0005622(intracellular);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0004930(G-protein coupled receptor activity);GO:0007186(G-protein coupled receptor signaling pathway);GO:0005886(plasma membrane);GO:0004871(signal transducer activity);GO:0007165(signal transduction);GO:0006955(immune response);GO:0004955(prostaglandin receptor activity);GO:0004957(prostaglandin E receptor activity);GO:0005515(protein binding);GO:0060348(bone development);GO:0050728(negative regulation of inflammatory response);GO:0070371(ERK1 and ERK2 cascade);GO:0071260(cellular response to mechanical stimulus);GO:0050729(positive regulation of inflammatory response);GO:0007254(JNK cascade);GO:0051492(regulation of stress fiber assembly);GO:0050715(positive regulation of cytokine secretion);GO:0009612(response to mechanical stimulus);GO:0050710(negative regulation of cytokine secretion);GO:0007188(adenylate cyclase-modulating G-protein coupled receptor signaling pathway);GO:0042093(T-helper cell differentiation);GO:0030278(regulation of ossification);GO:0032496(response to lipopolysaccharide);GO:0033624(negative regulation of integrin activation);GO:0071380(cellular response to prostaglandin E stimulus);GO:2000420(negative regulation of eosinophil extravasation)","04080(Neuroactive ligand-receptor interaction);04924(Renin secretion);04750(Inflammatory mediator regulation of TRP channels);05200(Pathways in cancer);05165(Human papillomavirus infection)","NA","NA","prostaglandin E receptor 4 [Source:HGNC Symbol;Acc:HGNC:9596]",{"v":0.363557,"d":"0.36"},{"v":0.011894,"d":"0.01"},{"v":30.5664200437195,"d":"30.57"},{"v":4.93387568775301,"d":"4.93"},1,1,"up","no"]
[155448,0,"chr5","-",69186359,69189452,"ENST00000624833",1,3094,"ENSG00000280187","AC022107.1","NA","NA","NA","NA","NA",{"v":0.098186,"d":"0.10"},{"v":0.014451,"d":"0.01"},{"v":6.79440869144004,"d":"6.79"},{"v":2.76434800058102,"d":"2.76"},1,1,"up","no"]
[110624,0,"chr2","-",69963282,70086399,"ENST00000626898",8,961,"MSTRG.8891","PCBP1-AS1","NA","NA","NA","NA","PCBP1 antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:42948]",{"v":0.133857,"d":"0.13"},{"v":0.048736,"d":"0.05"},{"v":2.74657337491793,"d":"2.75"},{"v":1.45763283407967,"d":"1.46"},1,1,"up","no"]
[19602,0,"chr10","-",34109561,34815321,"ENST00000374794",21,5669,"ENSG00000148498","PARD3","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0051301(cell division);GO:0005886(plasma membrane);GO:0030054(cell junction);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0007049(cell cycle);GO:0030154(cell differentiation);GO:0008289(lipid binding);GO:0005923(bicellular tight junction);GO:0005829(cytosol);GO:0007409(axonogenesis);GO:0032266(phosphatidylinositol-3-phosphate binding);GO:0005938(cell cortex);GO:0012505(endomembrane system);GO:0005546(phosphatidylinositol-4,5-bisphosphate binding);GO:0005547(phosphatidylinositol-3,4,5-trisphosphate binding);GO:0006612(protein targeting to membrane);GO:0006461(protein complex assembly);GO:0005911(cell-cell junction);GO:0007205(protein kinase C-activating G-protein coupled receptor signaling pathway);GO:0070830(bicellular tight junction assembly);GO:0090162(establishment of epithelial cell polarity);GO:0007163(establishment or maintenance of cell polarity);GO:0007179(transforming growth factor beta receptor signaling pathway);GO:0022011(myelination in peripheral nervous system);GO:0010801(negative regulation of peptidyl-threonine phosphorylation);GO:0031643(positive regulation of myelination);GO:0033269(internode region of axon);GO:0019903(protein phosphatase binding);GO:0008356(asymmetric cell division);GO:0060341(regulation of cellular localization);GO:0043025(neuronal cell body);GO:0043234(protein complex);GO:0044295(axonal growth cone)","04015(Rap1 signaling pathway);04390(Hippo signaling pathway);04080(Neuroactive ligand-receptor interaction);04144(Endocytosis);04520(Adherens junction);04530(Tight junction);04062(Chemokine signaling pathway);04360(Axon guidance);05165(Human papillomavirus infection)","K04237","NA","par-3 family cell polarity regulator [Source:HGNC Symbol;Acc:HGNC:16051]",0,0,1,0,1,1,"no","no"]
[201814,0,"chrY","-",13985772,13986513,"ENST00000250825",2,550,"ENSG00000129864","VCY","GO:0007420(brain development)","NA","NA","NA","variable charge, Y-linked [Source:HGNC Symbol;Acc:HGNC:12668]",0,{"v":0.031668,"d":"0.03"},"-inf","-inf",1,1,"down","no"]
[10430,0,"chr1","-",149676851,149747818,"ENST00000617878",5,1537,"MSTRG.903","AC243772.3","NA","NA","NA","NA","NA",{"v":0.004459,"d":"0.00"},{"v":0.015715,"d":"0.02"},{"v":0.283741648106904,"d":"0.28"},{"v":-1.81735016737221,"d":"-1.82"},1,1,"down","no"]
[59908,0,"chr15","+",22664359,22681605,"ENST00000611636",8,1609,"ENSG00000276141","WHAMMP3","NA","NA","NA","NA","WAS protein homolog associated with actin, golgi membranes and microtubules pseudogene 3 [Source:HGNC Symbol;Acc:HGNC:27892]",{"v":0.060049,"d":"0.06"},0,"inf","inf",1,1,"up","no"]
[7532,0,"chr1","+",81208568,81209210,"ENST00000426688",1,643,"ENSG00000235089","AL357632.1","NA","NA","NA","NA","NA",{"v":0.079941,"d":"0.08"},0,"inf","inf",1,1,"up","no"]
[151456,0,"chr4","-",151012829,151015727,"ENST00000510841",2,2288,"MSTRG.11855","LRBA","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005794(Golgi apparatus);GO:0005783(endoplasmic reticulum);GO:0005886(plasma membrane);GO:0005764(lysosome);GO:0003674(molecular_function);GO:0008150(biological_process)","NA","NA","NA","LPS responsive beige-like anchor protein [Source:HGNC Symbol;Acc:HGNC:1742]",{"v":0.026578,"d":"0.03"},{"v":0.012344,"d":"0.01"},{"v":2.15311082307194,"d":"2.15"},{"v":1.10642257857692,"d":"1.11"},1,1,"up","no"]
[93321,0,"chr18","-",69864314,69947853,"ENST00000582621",6,1458,"MSTRG.7554","CD226","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0007155(cell adhesion);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0050776(regulation of immune response);GO:0005887(integral component of plasma membrane);GO:0009986(cell surface);GO:0007165(signal transduction);GO:0019901(protein kinase binding);GO:0004872(receptor activity);GO:0042803(protein homodimerization activity);GO:0007156(homophilic cell adhesion via plasma membrane adhesion molecules);GO:0007157(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules);GO:0008037(cell recognition);GO:0045954(positive regulation of natural killer cell mediated cytotoxicity);GO:0005913(cell-cell adherens junction);GO:0045121(membrane raft);GO:0050839(cell adhesion molecule binding);GO:0005178(integrin binding);GO:0002860(positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target);GO:0002891(positive regulation of immunoglobulin mediated immune response);GO:0001816(cytokine production);GO:0002729(positive regulation of natural killer cell cytokine production);GO:0032729(positive regulation of interferon-gamma production);GO:0033005(positive regulation of mast cell activation);GO:0060369(positive regulation of Fc receptor mediated stimulatory signaling pathway);GO:0009897(external side of plasma membrane)","04514(Cell adhesion molecules (CAMs))","K06567","NA","CD226 molecule [Source:HGNC Symbol;Acc:HGNC:16961]",{"v":0.288278,"d":"0.29"},{"v":9.473588,"d":"9.47"},{"v":0.0304296534744808,"d":"0.03"},{"v":-5.03837828489016,"d":"-5.04"},1,1,"down","no"]
[143680,0,"chr3","-",185645501,185821131,"ENST00000421047",15,1711,"MSTRG.11396","IGF2BP2","GO:0005737(cytoplasm);GO:0005634(nucleus);GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0003729(mRNA binding);GO:0006810(transport);GO:0051028(mRNA transport);GO:0005829(cytosol);GO:0005515(protein binding);GO:0043488(regulation of mRNA stability);GO:0006417(regulation of translation);GO:0017148(negative regulation of translation);GO:0003730(mRNA 3'-UTR binding);GO:0045182(translation regulator activity);GO:0048027(mRNA 5'-UTR binding);GO:0009653(anatomical structure morphogenesis);GO:0042035(regulation of cytokine biosynthetic process);GO:0005856(cytoskeleton)","NA","NA","NA","insulin like growth factor 2 mRNA binding protein 2 [Source:HGNC Symbol;Acc:HGNC:28867]",0,0,1,0,1,1,"no","no"]
[28658,0,"chr11","+",47052461,47159811,"ENST00000526827",6,714,"MSTRG.2363","C11orf49","GO:0005515(protein binding)","NA","NA","NA","chromosome 11 open reading frame 49 [Source:HGNC Symbol;Acc:HGNC:28720]",0,0,1,0,1,1,"no","no"]
[114426,0,"chr2","+",130370433,130370917,"ENST00000464576",2,393,"MSTRG.9106","PTPN18","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016787(hydrolase activity);GO:0004725(protein tyrosine phosphatase activity);GO:0016791(phosphatase activity);GO:0006470(protein dephosphorylation);GO:0016311(dephosphorylation);GO:0035335(peptidyl-tyrosine dephosphorylation);GO:0004721(phosphoprotein phosphatase activity);GO:0005515(protein binding);GO:0005829(cytosol);GO:0038128(ERBB2 signaling pathway);GO:1901185(negative regulation of ERBB signaling pathway);GO:0004726(non-membrane spanning protein tyrosine phosphatase activity)","NA","NA","NA","protein tyrosine phosphatase, non-receptor type 18 [Source:HGNC Symbol;Acc:HGNC:9649]",{"v":0.587672,"d":"0.59"},{"v":0.217915,"d":"0.22"},{"v":2.69679462175619,"d":"2.70"},{"v":1.43124565525684,"d":"1.43"},1,1,"up","no"]
[32304,0,"chr11","+",68903926,68908192,"ENST00000545146",3,477,"MSTRG.2636","IGHMBP2","GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0006412(translation);GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0016787(hydrolase activity);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0004386(helicase activity);GO:0032508(DNA duplex unwinding);GO:0030529(intracellular ribonucleoprotein complex);GO:0042995(cell projection);GO:0000049(tRNA binding);GO:0043022(ribosome binding);GO:0005515(protein binding);GO:0030424(axon);GO:0030426(growth cone);GO:0008134(transcription factor binding);GO:0051260(protein homooligomerization);GO:0006281(DNA repair);GO:0008094(DNA-dependent ATPase activity);GO:0006310(DNA recombination);GO:0006260(DNA replication);GO:0003678(DNA helicase activity);GO:0003697(single-stranded DNA binding);GO:0008186(RNA-dependent ATPase activity);GO:0032575(ATP-dependent 5'-3' RNA helicase activity);GO:0043141(ATP-dependent 5'-3' DNA helicase activity)","NA","NA","NA","immunoglobulin mu binding protein 2 [Source:HGNC Symbol;Acc:HGNC:5542]",0,{"v":0.051412,"d":"0.05"},"-inf","-inf",1,1,"down","no"]
[6500,0,"chr1","-",56998025,57291066,"ENST00000420954",14,1817,"ENSG00000173406","DAB1","GO:0043231(intracellular membrane-bounded organelle);GO:0005515(protein binding);GO:0007275(multicellular organism development);GO:0007399(nervous system development);GO:0030154(cell differentiation);GO:0005829(cytosol);GO:0007411(axon guidance);GO:0043548(phosphatidylinositol 3-kinase binding);GO:0001764(neuron migration);GO:0007162(negative regulation of cell adhesion);GO:0007264(small GTPase mediated signal transduction);GO:0007420(brain development);GO:0007494(midgut development);GO:0007628(adult walking behavior);GO:0016358(dendrite development);GO:0021517(ventral spinal cord development);GO:0021589(cerebellum structural organization);GO:0021795(cerebral cortex cell migration);GO:0021799(cerebral cortex radially oriented cell migration);GO:0021813(cell-cell adhesion involved in neuronal-glial interactions involved in cerebral cortex radial glia guided migration);GO:0021942(radial glia guided migration of Purkinje cell);GO:0021987(cerebral cortex development);GO:0042493(response to drug);GO:0045666(positive regulation of neuron differentiation);GO:0045860(positive regulation of protein kinase activity);GO:0046426(negative regulation of JAK-STAT cascade);GO:0048712(negative regulation of astrocyte differentiation);GO:0050771(negative regulation of axonogenesis);GO:0051645(Golgi localization);GO:0097477(lateral motor column neuron migration);GO:0005903(brush border);GO:0014069(postsynaptic density);GO:0016020(membrane);GO:0043005(neuron projection);GO:0043025(neuronal cell body);GO:0045177(apical part of cell);GO:0048471(perinuclear region of cytoplasm)","NA","NA","NA","DAB1, reelin adaptor protein [Source:HGNC Symbol;Acc:HGNC:2661]",0,{"v":0.013217,"d":"0.01"},"-inf","-inf",1,1,"down","no"]
[175297,0,"chr7","-",76071469,76074963,"ENST00000421546",1,3495,"ENSG00000230882","AC005077.4","NA","NA","NA","NA","NA",{"v":0.014707,"d":"0.01"},0,"inf","inf",1,1,"up","no"]
[182028,0,"chr8","+",22404517,22408421,"ENST00000517552",2,576,"ENSG00000104635","SLC39A14","GO:0006810(transport);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0055085(transmembrane transport);GO:0006811(ion transport);GO:0005886(plasma membrane);GO:0042995(cell projection);GO:0046873(metal ion transmembrane transporter activity);GO:0030001(metal ion transport);GO:0030027(lamellipodium);GO:0006829(zinc II ion transport);GO:0005887(integral component of plasma membrane);GO:0071577(zinc II ion transmembrane transport);GO:1903874(ferrous iron transmembrane transport);GO:0005385(zinc ion transmembrane transporter activity);GO:0006882(cellular zinc ion homeostasis);GO:0071578(zinc II ion transmembrane import);GO:0015093(ferrous iron transmembrane transporter activity);GO:0006826(iron ion transport);GO:0015684(ferrous iron transport)","04216(Ferroptosis)","NA","NA","solute carrier family 39 member 14 [Source:HGNC Symbol;Acc:HGNC:20858]",{"v":0.318341,"d":"0.32"},{"v":0.188099,"d":"0.19"},{"v":1.69241197454532,"d":"1.69"},{"v":0.759080798533226,"d":"0.76"},1,1,"up","no"]
[83013,0,"chr17","-",40023289,40054408,"ENST00000580885",18,1963,"MSTRG.6799","MED24","GO:0005634(nucleus);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0005515(protein binding);GO:0030374(ligand-dependent nuclear receptor transcription coactivator activity);GO:0045893(positive regulation of transcription, DNA-templated);GO:0006367(transcription initiation from RNA polymerase II promoter);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0005654(nucleoplasm);GO:0016592(mediator complex);GO:0004872(receptor activity);GO:0003712(transcription cofactor activity);GO:0030518(intracellular steroid hormone receptor signaling pathway);GO:0030521(androgen receptor signaling pathway);GO:0001104(RNA polymerase II transcription cofactor activity);GO:0042809(vitamin D receptor binding);GO:0046966(thyroid hormone receptor binding);GO:1903506(regulation of nucleic acid-templated transcription);GO:0016573(histone acetylation);GO:0003713(transcription coactivator activity);GO:0004402(histone acetyltransferase activity);GO:0061630(ubiquitin protein ligase activity);GO:0006366(transcription from RNA polymerase II promoter);GO:0016567(protein ubiquitination);GO:0019827(stem cell population maintenance);GO:0051291(protein heterooligomerization);GO:0000151(ubiquitin ligase complex)","04919(Thyroid hormone signaling pathway)","NA","NA","mediator complex subunit 24 [Source:HGNC Symbol;Acc:HGNC:22963]",0,0,1,0,1,1,"no","no"]
[121755,0,"chr20","+",4181894,4187747,"ENST00000494098",4,812,"MSTRG.9581","SMOX","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0043231(intracellular membrane-bounded organelle);GO:0005654(nucleoplasm);GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0031965(nuclear membrane);GO:0005829(cytosol);GO:0006596(polyamine biosynthetic process);GO:0046592(polyamine oxidase activity);GO:0052901(spermine:oxygen oxidoreductase (spermidine-forming) activity);GO:0046208(spermine catabolic process);GO:0052894(norspermine:oxygen oxidoreductase activity);GO:0052895(N1-acetylspermine:oxygen oxidoreductase (N1-acetylspermidine-forming) activity);GO:0006598(polyamine catabolic process)","00330(Arginine and proline metabolism);00410(beta-Alanine metabolism)","NA","NA","spermine oxidase [Source:HGNC Symbol;Acc:HGNC:15862]",{"v":0.31112,"d":"0.31"},0,"inf","inf",1,1,"up","no"]
[7077,0,"chr1","-",68159184,68231825,"ENST00000527864",4,570,"MSTRG.637","WLS","GO:0090263(positive regulation of canonical Wnt signaling pathway);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005783(endoplasmic reticulum);GO:0005794(Golgi apparatus);GO:0005789(endoplasmic reticulum membrane);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0004871(signal transducer activity);GO:0000139(Golgi membrane);GO:0007275(multicellular organism development);GO:0016055(Wnt signaling pathway);GO:0030659(cytoplasmic vesicle membrane);GO:0031410(cytoplasmic vesicle);GO:0005768(endosome);GO:0017147(Wnt-protein binding);GO:0031901(early endosome membrane);GO:0043123(positive regulation of I-kappaB kinase/NF-kappaB signaling);GO:0030666(endocytic vesicle membrane);GO:0070062(extracellular exosome);GO:0005769(early endosome);GO:0005802(trans-Golgi network);GO:0006886(intracellular protein transport);GO:0009948(anterior/posterior axis specification);GO:0030177(positive regulation of Wnt signaling pathway);GO:0031852(mu-type opioid receptor binding);GO:0001707(mesoderm formation);GO:0030901(midbrain development);GO:0030902(hindbrain development);GO:0031017(exocrine pancreas development);GO:0061355(Wnt protein secretion);GO:0061357(positive regulation of Wnt protein secretion);GO:0032590(dendrite membrane);GO:0032839(dendrite cytoplasm)","NA","NA","NA","wntless Wnt ligand secretion mediator [Source:HGNC Symbol;Acc:HGNC:30238]",{"v":0.132818,"d":"0.13"},0,"inf","inf",1,1,"up","no"]
[149656,0,"chr4","-",101098418,101348278,"ENST00000529324",5,579,"MSTRG.11757","PPP3CA","GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0005634(nucleus);GO:0016020(membrane);GO:0046872(metal ion binding);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0016787(hydrolase activity);GO:0005886(plasma membrane);GO:0004721(phosphoprotein phosphatase activity);GO:0005515(protein binding);GO:0005509(calcium ion binding);GO:0038095(Fc-epsilon receptor signaling pathway);GO:0005516(calmodulin binding);GO:0098794(postsynapse);GO:0042383(sarcolemma);GO:0016311(dephosphorylation);GO:0019899(enzyme binding);GO:0042110(T cell activation);GO:0008144(drug binding);GO:0035690(cellular response to drug);GO:0006470(protein dephosphorylation);GO:0004722(protein serine/threonine phosphatase activity);GO:0007223(Wnt signaling pathway, calcium modulating pathway);GO:0046983(protein dimerization activity);GO:0051592(response to calcium ion);GO:0033192(calmodulin-dependent protein phosphatase activity);GO:0033173(calcineurin-NFAT signaling cascade);GO:0005955(calcineurin complex);GO:0016018(cyclosporin A binding);GO:0004723(calcium-dependent protein serine/threonine phosphatase activity);GO:0046982(protein heterodimerization activity);GO:0000082(G1/S transition of mitotic cell cycle);GO:0001975(response to amphetamine);GO:0006606(protein import into nucleus);GO:0006816(calcium ion transport);GO:0010613(positive regulation of cardiac muscle hypertrophy);GO:0010628(positive regulation of gene expression);GO:0010629(negative regulation of gene expression);GO:0014883(transition between fast and slow fiber);GO:0014898(cardiac muscle hypertrophy in response to stress);GO:0019722(calcium-mediated signaling);GO:0033555(multicellular organismal response to stress);GO:0035562(negative regulation of chromatin binding);GO:0045807(positive regulation of endocytosis);GO:0046676(negative regulation of insulin secretion);GO:0048741(skeletal muscle fiber development);GO:0050774(negative regulation of dendrite morphogenesis);GO:0050804(modulation of synaptic transmission);GO:0051091(positive regulation of sequence-specific DNA binding transcription factor activity);GO:0051533(positive regulation of NFAT protein import into nucleus);GO:0060079(excitatory postsynaptic potential);GO:0071333(cellular response to glucose stimulus);GO:1903244(positive regulation of cardiac muscle hypertrophy in response to stress);GO:1903799(negative regulation of production of miRNAs involved in gene silencing by miRNA);GO:1905205(positive regulation of connective tissue replacement);GO:0005739(mitochondrion);GO:0030018(Z disc)","04010(MAPK signaling pathway);04310(Wnt signaling pathway);04370(VEGF signaling pathway);04020(Calcium signaling pathway);04022(cGMP - PKG signaling pathway);04114(Oocyte meiosis);04218(Cellular senescence);04650(Natural killer cell mediated cytotoxicity);04660(T cell receptor signaling pathway);04658(Th1 and Th2 cell differentiation);04659(Th17 cell differentiation);04662(B cell receptor signaling pathway);04922(Glucagon signaling pathway);04921(Oxytocin signaling pathway);04924(Renin secretion);04724(Glutamatergic synapse);04728(Dopaminergic synapse);04720(Long-term potentiation);04360(Axon guidance);04380(Osteoclast differentiation);05010(Alzheimer's disease);05014(Amyotrophic lateral sclerosis (ALS));05031(Amphetamine addiction);05152(Tuberculosis);05166(HTLV-I infection);05167(Kaposi's sarcoma-associated herpesvirus infection)","NA","NA","protein phosphatase 3 catalytic subunit alpha [Source:HGNC Symbol;Acc:HGNC:9314]",{"v":0.159624,"d":"0.16"},{"v":0.01223,"d":"0.01"},{"v":13.0518397383483,"d":"13.05"},{"v":3.70618127289487,"d":"3.71"},1,1,"up","no"]
[43298,0,"chr12","+",57128716,57150059,"ENST00000338962",7,2169,"MSTRG.3478","LRP1","GO:0005730(nucleolus);GO:0005829(cytosol);GO:0005509(calcium ion binding);GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0046872(metal ion binding);GO:0005765(lysosomal membrane);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0007275(multicellular organism development);GO:0005905(clathrin-coated pit);GO:0005925(focal adhesion);GO:0006898(receptor-mediated endocytosis);GO:0005887(integral component of plasma membrane);GO:0006897(endocytosis);GO:0042953(lipoprotein transport);GO:0004872(receptor activity);GO:1904646(cellular response to amyloid-beta);GO:0030666(endocytic vesicle membrane);GO:0001523(retinoid metabolic process);GO:0043235(receptor complex);GO:0030178(negative regulation of Wnt signaling pathway);GO:0010942(positive regulation of cell death);GO:0014912(negative regulation of smooth muscle cell migration);GO:0034185(apolipoprotein binding);GO:0010875(positive regulation of cholesterol efflux);GO:0097242(amyloid-beta clearance);GO:0005041(low-density lipoprotein receptor activity);GO:0045807(positive regulation of endocytosis);GO:0051246(regulation of protein metabolic process);GO:1900223(positive regulation of amyloid-beta clearance);GO:1905167(positive regulation of lysosomal protein catabolic process);GO:0032374(regulation of cholesterol transport);GO:0032956(regulation of actin cytoskeleton organization);GO:0002265(astrocyte activation involved in immune response);GO:0035909(aorta morphogenesis);GO:0045732(positive regulation of protein catabolic process);GO:0005044(scavenger receptor activity);GO:0045056(transcytosis);GO:1903078(positive regulation of protein localization to plasma membrane);GO:0032403(protein complex binding);GO:0070325(lipoprotein particle receptor binding);GO:0006629(lipid metabolic process);GO:0098797(plasma membrane protein complex);GO:0002020(protease binding);GO:0016964(alpha-2 macroglobulin receptor activity);GO:0030226(apolipoprotein receptor activity);GO:0032050(clathrin heavy chain binding);GO:0042954(lipoprotein transporter activity);GO:0043395(heparan sulfate proteoglycan binding);GO:0006909(phagocytosis);GO:0007205(protein kinase C-activating G-protein coupled receptor signaling pathway);GO:0007568(aging);GO:0008283(cell proliferation);GO:0010715(regulation of extracellular matrix disassembly);GO:0010977(negative regulation of neuron projection development);GO:0021987(cerebral cortex development);GO:0031623(receptor internalization);GO:0032092(positive regulation of protein binding);GO:0032370(positive regulation of lipid transport);GO:0032429(regulation of phospholipase A2 activity);GO:0042157(lipoprotein metabolic process);GO:0043277(apoptotic cell clearance);GO:0043524(negative regulation of neuron apoptotic process);GO:0051222(positive regulation of protein transport);GO:2000587(negative regulation of platelet-derived growth factor receptor-beta signaling pathway);GO:0005768(endosome);GO:0005769(early endosome);GO:0016323(basolateral plasma membrane);GO:0030136(clathrin-coated vesicle);GO:0030425(dendrite);GO:0043025(neuronal cell body)","04979(Cholesterol metabolism);05010(Alzheimer's disease);05144(Malaria)","NA","NA","LDL receptor related protein 1 [Source:HGNC Symbol;Acc:HGNC:6692]",{"v":0.023699,"d":"0.02"},{"v":0.021035,"d":"0.02"},{"v":1.12664606608034,"d":"1.13"},{"v":0.172034366524075,"d":"0.17"},1,1,"up","no"]
[116326,0,"chr2","+",171443137,171450075,"ENST00000480855",3,811,"ENSG00000115827","DCAF17","GO:0005634(nucleus);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0016567(protein ubiquitination);GO:0005730(nucleolus);GO:0043687(post-translational protein modification);GO:0080008(Cul4-RING E3 ubiquitin ligase complex)","NA","NA","NA","DDB1 and CUL4 associated factor 17 [Source:HGNC Symbol;Acc:HGNC:25784]",0,0,1,0,1,1,"no","no"]
[73691,0,"chr16","-",57758720,57782309,"ENST00000562903",21,3221,"ENSG00000140859","KIFC3","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0003777(microtubule motor activity);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0008017(microtubule binding);GO:0030054(cell junction);GO:0005874(microtubule);GO:0030659(cytoplasmic vesicle membrane);GO:0031410(cytoplasmic vesicle);GO:0007018(microtubule-based movement);GO:0005813(centrosome);GO:0005815(microtubule organizing center);GO:0008569(ATP-dependent microtubule motor activity, minus-end-directed);GO:0070062(extracellular exosome);GO:0005912(adherens junction);GO:0016887(ATPase activity);GO:0007601(visual perception);GO:0005871(kinesin complex);GO:0090136(epithelial cell-cell adhesion);GO:0045218(zonula adherens maintenance);GO:0005915(zonula adherens);GO:0007017(microtubule-based process);GO:0007030(Golgi organization);GO:0005794(Golgi apparatus);GO:0003774(motor activity)","NA","NA","NA","kinesin family member C3 [Source:HGNC Symbol;Acc:HGNC:6326]",{"v":0.018403,"d":"0.02"},0,"inf","inf",1,1,"up","no"]
[27006,0,"chr11","+",17052025,17053024,"ENST00000526721",1,1000,"MSTRG.2283","OR7E14P","NA","NA","NA","NA","olfactory receptor family 7 subfamily E member 14 pseudogene [Source:HGNC Symbol;Acc:HGNC:8385]",0,{"v":0.045016,"d":"0.05"},"-inf","-inf",1,1,"down","no"]
[15155,0,"chr1","+",204516451,204546832,"ENST00000470908",9,884,"ENSG00000198625","MDM4","GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0043066(negative regulation of apoptotic process);GO:0016567(protein ubiquitination);GO:0008270(zinc ion binding);GO:0005515(protein binding);GO:0071157(negative regulation of cell cycle arrest);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0061630(ubiquitin protein ligase activity);GO:0006977(DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest);GO:0005654(nucleoplasm);GO:0050821(protein stabilization);GO:0016579(protein deubiquitination);GO:0008283(cell proliferation);GO:0019899(enzyme binding);GO:1901796(regulation of signal transduction by p53 class mediator);GO:0008285(negative regulation of cell proliferation);GO:0042177(negative regulation of protein catabolic process);GO:0006461(protein complex assembly);GO:0030330(DNA damage response, signal transduction by p53 class mediator);GO:0045023(G0 to G1 transition);GO:0071456(cellular response to hypoxia)","04115(p53 signaling pathway);05206(MicroRNAs in cancer)","NA","NA","MDM4, p53 regulator [Source:HGNC Symbol;Acc:HGNC:6974]",{"v":0.412917,"d":"0.41"},0,"inf","inf",1,1,"up","no"]
[132770,0,"chr3","-",3150011,3179710,"ENST00000432408",11,2203,"MSTRG.10618","CRBN","GO:0046872(metal ion binding);GO:0005730(nucleolus);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0016567(protein ubiquitination);GO:0005515(protein binding);GO:0032463(negative regulation of protein homooligomerization);GO:0034766(negative regulation of ion transmembrane transport);GO:0090073(positive regulation of protein homodimerization activity);GO:0043161(proteasome-mediated ubiquitin-dependent protein catabolic process);GO:0031464(Cul4A-RING E3 ubiquitin ligase complex)","NA","NA","NA","cereblon [Source:HGNC Symbol;Acc:HGNC:30185]",0,{"v":1.187776,"d":"1.19"},"-inf","-inf",1,1,"down","no"]
[59410,0,"chr14","+",105420016,105470238,"ENST00000438610",21,2144,"ENSG00000182979","MTA1","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0043231(intracellular membrane-bounded organelle);GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0016575(histone deacetylation);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0043565(sequence-specific DNA binding);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0048511(rhythmic process);GO:0005874(microtubule);GO:0003682(chromatin binding);GO:0003713(transcription coactivator activity);GO:1903507(negative regulation of nucleic acid-templated transcription);GO:0001047(core promoter binding);GO:0003714(transcription corepressor activity);GO:0007165(signal transduction);GO:0043161(proteasome-mediated ubiquitin-dependent protein catabolic process);GO:0032922(circadian regulation of gene expression);GO:0004407(histone deacetylase activity);GO:0001046(core promoter sequence-specific DNA binding);GO:0005635(nuclear envelope);GO:0001103(RNA polymerase II repressing transcription factor binding);GO:0016925(protein sumoylation);GO:0043153(entrainment of circadian clock by photoperiod);GO:0006302(double-strand break repair);GO:0040029(regulation of gene expression, epigenetic);GO:0045475(locomotor rhythm);GO:0010212(response to ionizing radiation);GO:1902499(positive regulation of protein autoubiquitination)","NA","NA","NA","metastasis associated 1 [Source:HGNC Symbol;Acc:HGNC:7410]",{"v":1.960625,"d":"1.96"},0,"inf","inf",1,1,"up","no"]
[64801,0,"chr15","-",74923594,74938066,"ENST00000564811",4,568,"MSTRG.5284","COX5A","GO:0016020(membrane);GO:0046872(metal ion binding);GO:0005743(mitochondrial inner membrane);GO:0005739(mitochondrion);GO:0005515(protein binding);GO:1902600(hydrogen ion transmembrane transport);GO:0004129(cytochrome-c oxidase activity);GO:0070062(extracellular exosome);GO:0006123(mitochondrial electron transport, cytochrome c to oxygen);GO:0009055(electron carrier activity);GO:0005751(mitochondrial respiratory chain complex IV);GO:0043209(myelin sheath)","00190(Oxidative phosphorylation);04260(Cardiac muscle contraction);05010(Alzheimer's disease);05012(Parkinson's disease);05016(Huntington's disease);04932(Non-alcoholic fatty liver disease (NAFLD))","NA","NA","cytochrome c oxidase subunit 5A [Source:HGNC Symbol;Acc:HGNC:2267]",{"v":0.599528,"d":"0.60"},{"v":3.214596,"d":"3.21"},{"v":0.186501818580002,"d":"0.19"},{"v":-2.42273839661297,"d":"-2.42"},1,1,"down","no"]
[51814,0,"chr13","-",110893197,110914617,"ENST00000494859",6,705,"MSTRG.4101","ANKRD10","GO:0005515(protein binding);GO:0060828(regulation of canonical Wnt signaling pathway)","NA","NA","NA","ankyrin repeat domain 10 [Source:HGNC Symbol;Acc:HGNC:20265]",{"v":0.067318,"d":"0.07"},{"v":0.268426,"d":"0.27"},{"v":0.250787926653901,"d":"0.25"},{"v":-1.99546019880406,"d":"-2.00"},1,1,"down","no"]
[44374,0,"chr12","+",70278132,70332846,"ENST00000551873",5,677,"MSTRG.3565","CNOT2","GO:0005634(nucleus);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0006355(regulation of transcription, DNA-templated);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0006351(transcription, DNA-templated);GO:0005515(protein binding);GO:0007275(multicellular organism development);GO:0031047(gene silencing by RNA);GO:0010606(positive regulation of cytoplasmic mRNA processing body assembly);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0006977(DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest);GO:0004535(poly(A)-specific ribonuclease activity);GO:0000289(nuclear-transcribed mRNA poly(A) tail shortening);GO:0006417(regulation of translation);GO:0033147(negative regulation of intracellular estrogen receptor signaling pathway);GO:0090503(RNA phosphodiester bond hydrolysis, exonucleolytic);GO:2000036(regulation of stem cell population maintenance);GO:0030014(CCR4-NOT complex);GO:0030015(CCR4-NOT core complex);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0000932(P-body);GO:0000288(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay);GO:0001104(RNA polymerase II transcription cofactor activity);GO:0017148(negative regulation of translation);GO:0001226(RNA polymerase II transcription corepressor binding);GO:0001829(trophectodermal cell differentiation)","03018(RNA degradation)","NA","NA","CCR4-NOT transcription complex subunit 2 [Source:HGNC Symbol;Acc:HGNC:7878]",{"v":0.939168,"d":"0.94"},0,"inf","inf",1,1,"up","no"]
[68180,0,"chr16","+",2066229,2071534,"ENST00000562474",4,589,"MSTRG.5539","TSC2","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005829(cytosol);GO:0005794(Golgi apparatus);GO:0032007(negative regulation of TOR signaling);GO:0042803(protein homodimerization activity);GO:0005515(protein binding);GO:0005096(GTPase activator activity);GO:0048471(perinuclear region of cytoplasm);GO:0043547(positive regulation of GTPase activity);GO:0051056(regulation of small GTPase mediated signal transduction);GO:0005764(lysosome);GO:0007507(heart development);GO:0008285(negative regulation of cell proliferation);GO:0061024(membrane organization);GO:0016032(viral process);GO:0019902(phosphatase binding);GO:0033596(TSC1-TSC2 complex);GO:0016192(vesicle-mediated transport);GO:0046627(negative regulation of insulin receptor signaling pathway);GO:0006469(negative regulation of protein kinase activity);GO:0014067(negative regulation of phosphatidylinositol 3-kinase signaling);GO:0051898(negative regulation of protein kinase B signaling);GO:0001843(neural tube closure);GO:0046626(regulation of insulin receptor signaling pathway);GO:0050918(positive chemotaxis);GO:0007050(cell cycle arrest);GO:0008104(protein localization);GO:0051726(regulation of cell cycle);GO:0030100(regulation of endocytosis);GO:0006897(endocytosis);GO:0043491(protein kinase B signaling);GO:0048009(insulin-like growth factor receptor signaling pathway);GO:0043276(anoikis);GO:0006606(protein import into nucleus);GO:0031267(small GTPase binding);GO:0016239(positive regulation of macroautophagy);GO:0030178(negative regulation of Wnt signaling pathway);GO:1901525(negative regulation of macromitophagy)","04072(Phospholipase D signaling pathway);04151(PI3K-Akt signaling pathway);04152(AMPK signaling pathway);04150(mTOR signaling pathway);04140(Autophagy - animal);04115(p53 signaling pathway);04218(Cellular senescence);04910(Insulin signaling pathway);04919(Thyroid hormone signaling pathway);04211(Longevity regulating pathway - mammal);05231(Choline metabolism in cancer);05165(Human papillomavirus infection)","NA","NA","tuberous sclerosis 2 [Source:HGNC Symbol;Acc:HGNC:12363]",{"v":0.153527,"d":"0.15"},{"v":0.075782,"d":"0.08"},{"v":2.02590324879259,"d":"2.03"},{"v":1.0185652768932,"d":"1.02"},1,1,"up","no"]
[64668,0,"chr15","-",74655794,74695987,"ENST00000563009",5,967,"MSTRG.5282","EDC3","GO:0003723(RNA binding);GO:0003729(mRNA binding);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005515(protein binding);GO:0090502(RNA phosphodiester bond hydrolysis, endonucleolytic);GO:0000932(P-body);GO:0042802(identical protein binding);GO:0005829(cytosol);GO:0033962(cytoplasmic mRNA processing body assembly);GO:0031087(deadenylation-independent decapping of nuclear-transcribed mRNA);GO:0043928(exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay);GO:1990174(phosphodiesterase decapping endonuclease activity)","03018(RNA degradation)","NA","NA","enhancer of mRNA decapping 3 [Source:HGNC Symbol;Acc:HGNC:26114]",{"v":0.752156,"d":"0.75"},0,"inf","inf",1,1,"up","no"]
[94450,0,"chr19","-",1815970,1819963,"ENST00000590936",10,1271,"MSTRG.7617","REXO1","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0016787(hydrolase activity);GO:0090305(nucleic acid phosphodiester bond hydrolysis);GO:0016604(nuclear body);GO:0004527(exonuclease activity);GO:0004518(nuclease activity)","03008(Ribosome biogenesis in eukaryotes)","NA","NA","RNA exonuclease 1 homolog [Source:HGNC Symbol;Acc:HGNC:24616]",{"v":0.399819,"d":"0.40"},{"v":1.225848,"d":"1.23"},{"v":0.326157076570668,"d":"0.33"},{"v":-1.61636116413511,"d":"-1.62"},1,1,"down","no"]
[39585,0,"chr12","-",22248826,22334163,"ENST00000541868",4,695,"ENSG00000111728","ST8SIA1","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016740(transferase activity);GO:0008373(sialyltransferase activity);GO:0016757(transferase activity, transferring glycosyl groups);GO:0006486(protein glycosylation);GO:0097503(sialylation);GO:0005794(Golgi apparatus);GO:0006629(lipid metabolic process);GO:0000139(Golgi membrane);GO:0006665(sphingolipid metabolic process);GO:0005975(carbohydrate metabolic process);GO:0003828(alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity);GO:0006688(glycosphingolipid biosynthetic process);GO:0008284(positive regulation of cell proliferation);GO:0034605(cellular response to heat)","00601(Glycosphingolipid biosynthesis - lacto and neolacto series);00603(Glycosphingolipid biosynthesis - globo and isoglobo series);00604(Glycosphingolipid biosynthesis - ganglio series)","NA","NA","ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:10869]",0,0,1,0,1,1,"no","no"]
[120395,0,"chr2","+",233438313,233472104,"ENST00000430834",23,5379,"MSTRG.9505","DGKD","GO:0005634(nucleus);GO:0006810(transport);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0015031(protein transport);GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0005829(cytosol);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0035556(intracellular signal transduction);GO:0008152(metabolic process);GO:0003951(NAD+ kinase activity);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0007165(signal transduction);GO:0007275(multicellular organism development);GO:0004143(diacylglycerol kinase activity);GO:0007205(protein kinase C-activating G-protein coupled receptor signaling pathway);GO:0006897(endocytosis);GO:0030168(platelet activation);GO:0010033(response to organic substance);GO:0007173(epidermal growth factor receptor signaling pathway);GO:0042803(protein homodimerization activity);GO:0046982(protein heterodimerization activity);GO:0016049(cell growth);GO:0051260(protein homooligomerization);GO:0046834(lipid phosphorylation);GO:0019992(diacylglycerol binding);GO:0019932(second-messenger-mediated signaling);GO:0046339(diacylglycerol metabolic process);GO:0005622(intracellular)","00561(Glycerolipid metabolism);00564(Glycerophospholipid metabolism);04070(Phosphatidylinositol signaling system);04072(Phospholipase D signaling pathway);05231(Choline metabolism in cancer)","NA","NA","diacylglycerol kinase delta [Source:HGNC Symbol;Acc:HGNC:2851]",0,{"v":0.023849,"d":"0.02"},"-inf","-inf",1,1,"down","no"]
[161181,0,"chr5","-",173607933,173616653,"ENST00000480951",2,814,"ENSG00000145919","BOD1","GO:0005737(cytoplasm);GO:0051301(cell division);GO:0005694(chromosome);GO:0005856(cytoskeleton);GO:0007049(cell cycle);GO:0005815(microtubule organizing center);GO:0000775(chromosome, centromeric region);GO:0000776(kinetochore);GO:0000777(condensed chromosome kinetochore)","NA","NA","NA","biorientation of chromosomes in cell division 1 [Source:HGNC Symbol;Acc:HGNC:25114]",{"v":0.025641,"d":"0.03"},{"v":0.073609,"d":"0.07"},{"v":0.348340556181989,"d":"0.35"},{"v":-1.52142964379327,"d":"-1.52"},1,1,"down","no"]
[135990,0,"chr3","-",48694175,48717249,"ENST00000412795",5,750,"MSTRG.10909","IP6K2","GO:0005634(nucleus);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0045111(intermediate filament cytoskeleton);GO:0008440(inositol-1,4,5-trisphosphate 3-kinase activity);GO:0005515(protein binding);GO:0005654(nucleoplasm);GO:0043065(positive regulation of apoptotic process);GO:0006817(phosphate ion transport);GO:0030308(negative regulation of cell growth);GO:0043647(inositol phosphate metabolic process);GO:0060337(type I interferon signaling pathway);GO:0000828(inositol hexakisphosphate kinase activity);GO:0000829(inositol heptakisphosphate kinase activity);GO:0000832(inositol hexakisphosphate 5-kinase activity);GO:0052723(inositol hexakisphosphate 1-kinase activity);GO:0052724(inositol hexakisphosphate 3-kinase activity);GO:0046854(phosphatidylinositol phosphorylation);GO:0000827(inositol-1,3,4,5,6-pentakisphosphate kinase activity);GO:0052836(inositol 5-diphosphate pentakisphosphate 5-kinase activity);GO:0052839(inositol diphosphate tetrakisphosphate kinase activity)","04070(Phosphatidylinositol signaling system)","NA","NA","inositol hexakisphosphate kinase 2 [Source:HGNC Symbol;Acc:HGNC:17313]",0,{"v":0.003573,"d":"0.00"},"-inf","-inf",1,1,"down","no"]
[84035,0,"chr17","-",43952738,44004469,"ENST00000360085",7,1053,"ENSG00000131096","PYY","GO:0005576(extracellular region);GO:0005515(protein binding);GO:0005179(hormone activity);GO:0005615(extracellular space);GO:0001664(G-protein coupled receptor binding);GO:0007186(G-protein coupled receptor signaling pathway);GO:0007267(cell-cell signaling);GO:0007631(feeding behavior);GO:0006928(movement of cell or subcellular component);GO:0008283(cell proliferation);GO:0007586(digestion);GO:0007010(cytoskeleton organization);GO:0005184(neuropeptide hormone activity);GO:0007218(neuropeptide signaling pathway);GO:0032098(regulation of appetite)","04080(Neuroactive ligand-receptor interaction)","K05233","NA","peptide YY [Source:HGNC Symbol;Acc:HGNC:9748]",0,{"v":0.132469,"d":"0.13"},"-inf","-inf",1,1,"down","no"]
[38830,"j","chr12","-",10372346,10410128,"MSTRG.3171.3",14,2097,"MSTRG.3171","KLRC4-KLRK1","NA","NA","NA","NA","NA",{"v":0.116594,"d":"0.12"},0,"inf","inf",1,1,"up","no"]
[80248,0,"chr17","-",18246153,18247125,"ENST00000580453",4,673,"MSTRG.6497","FLII","GO:0051015(actin filament binding);GO:0030036(actin cytoskeleton organization);GO:0051014(actin filament severing);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0005815(microtubule organizing center);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003779(actin binding);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0007275(multicellular organism development);GO:0030054(cell junction);GO:0005925(focal adhesion);GO:0005903(brush border)","NA","NA","NA","FLII, actin remodeling protein [Source:HGNC Symbol;Acc:HGNC:3750]",{"v":0.938126,"d":"0.94"},{"v":0.316797,"d":"0.32"},{"v":2.9612843555968,"d":"2.96"},{"v":1.56622303111401,"d":"1.57"},1,1,"up","no"]
[92079,0,"chr18","+",45825512,45842556,"ENST00000389474",6,1573,"ENSG00000197046","SIGLEC15","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005886(plasma membrane);GO:0045087(innate immune response);GO:0032956(regulation of actin cytoskeleton organization);GO:0045124(regulation of bone resorption);GO:0071402(cellular response to lipoprotein particle stimulus);GO:2001204(regulation of osteoclast development);GO:0043234(protein complex)","NA","NA","NA","sialic acid binding Ig like lectin 15 [Source:HGNC Symbol;Acc:HGNC:27596]",0,0,1,0,1,1,"no","no"]
[198617,0,"chrX","+",85244032,85273360,"ENST00000373165",9,4124,"ENSG00000147180","ZNF711","GO:0005634(nucleus);GO:0003676(nucleic acid binding);GO:0046872(metal ion binding);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0045893(positive regulation of transcription, DNA-templated);GO:0005515(protein binding);GO:0070062(extracellular exosome);GO:0043565(sequence-specific DNA binding)","NA","NA","NA","zinc finger protein 711 [Source:HGNC Symbol;Acc:HGNC:13128]",0,{"v":0.013019,"d":"0.01"},"-inf","-inf",1,1,"down","no"]
[184374,0,"chr8","-",66419589,66428977,"ENST00000499642",3,4366,"ENSG00000246145","RRS1-AS1","NA","NA","NA","NA","RRS1 antisense RNA 1 (head to head) [Source:HGNC Symbol;Acc:HGNC:50465]",{"v":5.633E-3,"d":"0.01"},{"v":0.003414,"d":"0.00"},{"v":1.64997070884593,"d":"1.65"},{"v":0.72244041321181,"d":"0.72"},1,1,"up","no"]
[27947,0,"chr11","+",34052055,34076429,"ENST00000534825",5,668,"MSTRG.2318","CAPRIN1","GO:0003723(RNA binding);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005829(cytosol);GO:0042995(cell projection);GO:0030154(cell differentiation);GO:0030425(dendrite);GO:0000932(P-body);GO:0005887(integral component of plasma membrane);GO:0017148(negative regulation of translation);GO:0010494(cytoplasmic stress granule);GO:0005515(protein binding);GO:0050775(positive regulation of dendrite morphogenesis);GO:0061003(positive regulation of dendritic spine morphogenesis)","NA","NA","NA","cell cycle associated protein 1 [Source:HGNC Symbol;Acc:HGNC:6743]",0,0,1,0,1,1,"no","no"]
[195786,0,"chrX","-",14843407,14873062,"ENST00000398334",10,3008,"ENSG00000181544","FANCB","GO:0005634(nucleus);GO:0005515(protein binding);GO:0006281(DNA repair);GO:0006974(cellular response to DNA damage stimulus);GO:0043240(Fanconi anaemia nuclear complex);GO:0005654(nucleoplasm);GO:0036297(interstrand cross-link repair)","03460(Fanconi anemia pathway)","K10889","NA","Fanconi anemia complementation group B [Source:HGNC Symbol;Acc:HGNC:3583]",{"v":0.10418,"d":"0.10"},{"v":0.134131,"d":"0.13"},{"v":0.776703372076552,"d":"0.78"},{"v":-0.36456436541903,"d":"-0.36"},1,1,"down","no"]
[21197,0,"chr10","-",73183362,73245981,"ENST00000469143",3,362,"MSTRG.1791","DNAJC9","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0005886(plasma membrane);GO:0005615(extracellular space);GO:0032781(positive regulation of ATPase activity);GO:0035176(social behavior);GO:0031072(heat shock protein binding)","NA","NA","NA","DnaJ heat shock protein family (Hsp40) member C9 [Source:HGNC Symbol;Acc:HGNC:19123]",0,0,1,0,1,1,"no","no"]
[105075,0,"chr19","+",53013921,53016122,"ENST00000602168",1,2202,"ENSG00000269526","ERVV-1","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0019031(viral envelope)","NA","NA","NA","endogenous retrovirus group V member 1, envelope [Source:HGNC Symbol;Acc:HGNC:26501]",{"v":0.046687,"d":"0.05"},{"v":0.029352,"d":"0.03"},{"v":1.59059007904061,"d":"1.59"},{"v":0.669562077570747,"d":"0.67"},1,1,"up","no"]
[145426,0,"chr4","+",2824665,2829734,"ENST00000515183",5,566,"MSTRG.11502","SH3BP2","GO:0009967(positive regulation of signal transduction);GO:0005515(protein binding);GO:0017124(SH3 domain binding);GO:0007165(signal transduction);GO:0001784(phosphotyrosine residue binding);GO:0005070(SH3/SH2 adaptor activity)","04650(Natural killer cell mediated cytotoxicity)","NA","NA","SH3 domain binding protein 2 [Source:HGNC Symbol;Acc:HGNC:10825]",{"v":0.117221,"d":"0.12"},{"v":0.395766,"d":"0.40"},{"v":0.296187646235402,"d":"0.30"},{"v":-1.75541662673394,"d":"-1.76"},1,1,"down","no"]
[133771,0,"chr3","-",15579900,15601592,"ENST00000421993",8,861,"MSTRG.10704","HACL1","GO:0043231(intracellular membrane-bounded organelle);GO:0046872(metal ion binding);GO:0000287(magnesium ion binding);GO:0003824(catalytic activity);GO:0016829(lyase activity);GO:0006631(fatty acid metabolic process);GO:0005515(protein binding);GO:0048037(cofactor binding);GO:0005777(peroxisome);GO:0042802(identical protein binding);GO:0030976(thiamine pyrophosphate binding);GO:0005102(receptor binding);GO:0005782(peroxisomal matrix);GO:0051259(protein oligomerization);GO:0001561(fatty acid alpha-oxidation);GO:0016830(carbon-carbon lyase activity);GO:0006629(lipid metabolic process)","04146(Peroxisome)","NA","NA","2-hydroxyacyl-CoA lyase 1 [Source:HGNC Symbol;Acc:HGNC:17856]",{"v":1.94E-4,"d":"0.00"},0,"inf","inf",1,1,"up","no"]
[56921,0,"chr14","-",75053237,75069483,"ENST00000555463",3,789,"MSTRG.4549","ACYP1","GO:0016787(hydrolase activity);GO:0003998(acylphosphatase activity);GO:0070062(extracellular exosome);GO:0006796(phosphate-containing compound metabolic process)","00620(Pyruvate metabolism)","K01512","EC:3.6.1.7","acylphosphatase 1 [Source:HGNC Symbol;Acc:HGNC:179]",0,0,1,0,1,1,"no","no"]
[158496,0,"chr5","+",134846096,134859732,"ENST00000504727",3,2923,"MSTRG.12316","C5orf24","GO:0005515(protein binding)","NA","NA","NA","chromosome 5 open reading frame 24 [Source:HGNC Symbol;Acc:HGNC:26746]",0,0,1,0,1,1,"no","no"]
[173718,0,"chr7","+",44606628,44708994,"ENST00000631326",23,4121,"MSTRG.13632","OGDH","GO:0055114(oxidation-reduction process);GO:0006099(tricarboxylic acid cycle);GO:0005739(mitochondrion);GO:0008152(metabolic process);GO:0016624(oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor);GO:0004591(oxoglutarate dehydrogenase (succinyl-transferring) activity);GO:0030976(thiamine pyrophosphate binding);GO:0046872(metal ion binding);GO:0016491(oxidoreductase activity);GO:0006096(glycolytic process);GO:0005759(mitochondrial matrix);GO:0031966(mitochondrial membrane);GO:0006554(lysine catabolic process);GO:0034641(cellular nitrogen compound metabolic process);GO:0006091(generation of precursor metabolites and energy);GO:0045252(oxoglutarate dehydrogenase complex);GO:0031072(heat shock protein binding);GO:0034602(oxoglutarate dehydrogenase (NAD+) activity);GO:0051087(chaperone binding);GO:0006103(2-oxoglutarate metabolic process);GO:0006104(succinyl-CoA metabolic process);GO:0006734(NADH metabolic process);GO:0021695(cerebellar cortex development);GO:0021756(striatum development);GO:0021766(hippocampus development);GO:0021794(thalamus development);GO:0021860(pyramidal neuron development);GO:0022028(tangential migration from the subventricular zone to the olfactory bulb);GO:0061034(olfactory bulb mitral cell layer development)","00020(Citrate cycle (TCA cycle));00310(Lysine degradation);00380(Tryptophan metabolism)","NA","NA","oxoglutarate dehydrogenase [Source:HGNC Symbol;Acc:HGNC:8124]",0,{"v":0.00015,"d":"0.00"},"-inf","-inf",1,1,"down","no"]
[49751,0,"chr13","-",37040417,37059639,"ENST00000470359",10,792,"MSTRG.3954","SUPT20H","GO:1903506(regulation of nucleic acid-templated transcription);GO:0000124(SAGA complex);GO:0003712(transcription cofactor activity);GO:0005634(nucleus);GO:0001650(fibrillar center);GO:0005515(protein binding);GO:0007275(multicellular organism development);GO:0006914(autophagy);GO:0007369(gastrulation);GO:0070461(SAGA-type complex)","04140(Autophagy - animal)","NA","NA","SPT20 homolog, SAGA complex component [Source:HGNC Symbol;Acc:HGNC:20596]",{"v":0.379754,"d":"0.38"},0,"inf","inf",1,1,"up","no"]
[30688,0,"chr11","+",64241003,64243669,"ENST00000536642",4,637,"MSTRG.2501","FKBP2","GO:0016020(membrane);GO:0016853(isomerase activity);GO:0003755(peptidyl-prolyl cis-trans isomerase activity);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005515(protein binding);GO:0000413(protein peptidyl-prolyl isomerization);GO:0061077(chaperone-mediated protein folding);GO:0070062(extracellular exosome);GO:0005528(FK506 binding)","NA","NA","NA","FK506 binding protein 2 [Source:HGNC Symbol;Acc:HGNC:3718]",{"v":0.387262,"d":"0.39"},{"v":0.07155,"d":"0.07"},{"v":5.41246680642907,"d":"5.41"},{"v":2.43628627210781,"d":"2.44"},1,1,"up","no"]
[109791,0,"chr2","+",55232432,55234959,"ENST00000449323",5,422,"MSTRG.8715","RPS27A","GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0006412(translation);GO:0046872(metal ion binding);GO:0030529(intracellular ribonucleoprotein complex);GO:0003735(structural constituent of ribosome);GO:0005840(ribosome);GO:0005515(protein binding);GO:0044322(endoplasmic reticulum quality control compartment);GO:0022627(cytosolic small ribosomal subunit);GO:0005615(extracellular space);GO:0005730(nucleolus);GO:0038095(Fc-epsilon receptor signaling pathway);GO:0005886(plasma membrane);GO:0016567(protein ubiquitination);GO:0005789(endoplasmic reticulum membrane);GO:0006977(DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0034220(ion transmembrane transport);GO:0044267(cellular protein metabolic process);GO:0061024(membrane organization);GO:0016197(endosomal transport);GO:0019058(viral life cycle);GO:0075733(intracellular transport of virus);GO:0010008(endosome membrane);GO:0043657(host cell);GO:0000165(MAPK cascade);GO:0000209(protein polyubiquitination);GO:0002223(stimulatory C-type lectin receptor signaling pathway);GO:0010972(negative regulation of G2/M transition of mitotic cell cycle);GO:0016579(protein deubiquitination);GO:0031145(anaphase-promoting complex-dependent catabolic process);GO:0031146(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process);GO:0033209(tumor necrosis factor-mediated signaling pathway);GO:0038061(NIK/NF-kappaB signaling);GO:0043161(proteasome-mediated ubiquitin-dependent protein catabolic process);GO:0043488(regulation of mRNA stability);GO:0050852(T cell receptor signaling pathway);GO:0051437(positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition);GO:0055085(transmembrane transport);GO:0060071(Wnt signaling pathway, planar cell polarity pathway);GO:0061418(regulation of transcription from RNA polymerase II promoter in response to hypoxia);GO:0090090(negative regulation of canonical Wnt signaling pathway);GO:0090263(positive regulation of canonical Wnt signaling pathway);GO:1902036(regulation of hematopoietic stem cell differentiation);GO:0045087(innate immune response);GO:0000086(G2/M transition of mitotic cell cycle);GO:0036297(interstrand cross-link repair);GO:0006457(protein folding);GO:0002755(MyD88-dependent toll-like receptor signaling pathway);GO:0002756(MyD88-independent toll-like receptor signaling pathway);GO:0007249(I-kappaB kinase/NF-kappaB signaling);GO:0035666(TRIF-dependent toll-like receptor signaling pathway);GO:0051436(negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle);GO:1904380(endoplasmic reticulum mannose trimming);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:1901796(regulation of signal transduction by p53 class mediator);GO:0031982(vesicle);GO:0006413(translational initiation);GO:0030666(endocytic vesicle membrane);GO:0005741(mitochondrial outer membrane);GO:0006364(rRNA processing);GO:0007219(Notch signaling pathway);GO:0016055(Wnt signaling pathway);GO:0042787(protein ubiquitination involved in ubiquitin-dependent protein catabolic process);GO:0038128(ERBB2 signaling pathway);GO:0007254(JNK cascade);GO:0043065(positive regulation of apoptotic process);GO:0010803(regulation of tumor necrosis factor-mediated signaling pathway);GO:0043066(negative regulation of apoptotic process);GO:0043123(positive regulation of I-kappaB kinase/NF-kappaB signaling);GO:0051092(positive regulation of NF-kappaB transcription factor activity);GO:0051403(stress-activated MAPK cascade);GO:0070423(nucleotide-binding oligomerization domain containing signaling pathway);GO:0019985(translesion synthesis);GO:0032480(negative regulation of type I interferon production);GO:0042059(negative regulation of epidermal growth factor receptor signaling pathway);GO:0030512(negative regulation of transforming growth factor beta receptor signaling pathway);GO:0000184(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay);GO:0005978(glycogen biosynthetic process);GO:0019083(viral transcription);GO:0006283(transcription-coupled nucleotide-excision repair);GO:0008543(fibroblast growth factor receptor signaling pathway);GO:0000187(activation of MAPK activity);GO:0016236(macroautophagy);GO:0042276(error-prone translesion synthesis);GO:0035635(entry of bacterium into host cell);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0006614(SRP-dependent cotranslational protein targeting to membrane);GO:0042769(DNA damage response, detection of DNA damage);GO:0007179(transforming growth factor beta receptor signaling pathway);GO:0006879(cellular iron ion homeostasis);GO:0006296(nucleotide-excision repair, DNA incision, 5'-to lesion);GO:0033683(nucleotide-excision repair, DNA incision);GO:0070911(global genome nucleotide-excision repair);GO:0000715(nucleotide-excision repair, DNA damage recognition);GO:0000717(nucleotide-excision repair, DNA duplex unwinding);GO:0006294(nucleotide-excision repair, preincision complex assembly);GO:0006297(nucleotide-excision repair, DNA gap filling);GO:0019068(virion assembly);GO:0032479(regulation of type I interferon production);GO:0045742(positive regulation of epidermal growth factor receptor signaling pathway);GO:0060544(regulation of necroptotic process);GO:0070987(error-free translesion synthesis);GO:0015935(small ribosomal subunit);GO:0043209(myelin sheath)","03010(Ribosome)","NA","NA","ribosomal protein S27a [Source:HGNC Symbol;Acc:HGNC:10417]",0,0,1,0,1,1,"no","no"]
[25413,0,"chr11","+",2400536,2403876,"ENST00000333256",3,1686,"MSTRG.2113","TSSC4","GO:0005515(protein binding)","NA","NA","NA","tumor suppressing subtransferable candidate 4 [Source:HGNC Symbol;Acc:HGNC:12386]",0,{"v":2.035479,"d":"2.04"},"-inf","-inf",1,1,"down","no"]
[120205,0,"chr2","-",232479827,232487821,"ENST00000482346",17,2965,"ENSG00000171551","ECEL1","GO:0006508(proteolysis);GO:0004222(metalloendopeptidase activity);GO:0008237(metallopeptidase activity);GO:0007218(neuropeptide signaling pathway);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0046872(metal ion binding);GO:0016787(hydrolase activity);GO:0008233(peptidase activity);GO:0005887(integral component of plasma membrane);GO:0003016(respiratory system process)","NA","NA","NA","endothelin converting enzyme like 1 [Source:HGNC Symbol;Acc:HGNC:3147]",{"v":0.027755,"d":"0.03"},{"v":0.013784,"d":"0.01"},{"v":2.01356645385955,"d":"2.01"},{"v":1.009753086424,"d":"1.01"},1,1,"up","no"]
[190042,0,"chr9","+",35658317,35661177,"ENST00000327351",6,804,"MSTRG.14750","CCDC107","GO:0016020(membrane);GO:0016021(integral component of membrane)","NA","NA","NA","coiled-coil domain containing 107 [Source:HGNC Symbol;Acc:HGNC:28465]",0,{"v":0.069044,"d":"0.07"},"-inf","-inf",1,1,"down","no"]
[1216,0,"chr1","+",7961748,7971521,"ENST00000465354",5,949,"MSTRG.116","PARK7","GO:0048471(perinuclear region of cytoplasm);GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005829(cytosol);GO:0016787(hydrolase activity);GO:0005739(mitochondrion);GO:0042803(protein homodimerization activity);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0008233(peptidase activity);GO:0006508(proteolysis);GO:0006914(autophagy);GO:0098793(presynapse);GO:0045121(membrane raft);GO:0098869(cellular oxidant detoxification);GO:0006954(inflammatory response);GO:0042802(identical protein binding);GO:0003729(mRNA binding);GO:0045296(cadherin binding);GO:0070062(extracellular exosome);GO:0050821(protein stabilization);GO:0007338(single fertilization);GO:0005102(receptor binding);GO:0005913(cell-cell adherens junction);GO:0005507(copper ion binding);GO:0051897(positive regulation of protein kinase B signaling);GO:0032091(negative regulation of protein binding);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0008134(transcription factor binding);GO:0007005(mitochondrion organization);GO:1903206(negative regulation of hydrogen peroxide-induced cell death);GO:2001237(negative regulation of extrinsic apoptotic signaling pathway);GO:0019900(kinase binding);GO:0051091(positive regulation of sequence-specific DNA binding transcription factor activity);GO:0034599(cellular response to oxidative stress);GO:1901215(negative regulation of neuron death);GO:0000785(chromatin);GO:0060548(negative regulation of cell death);GO:1902236(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway);GO:0019899(enzyme binding);GO:1990381(ubiquitin-specific protease binding);GO:0010628(positive regulation of gene expression);GO:0010629(negative regulation of gene expression);GO:0043524(negative regulation of neuron apoptotic process);GO:1903202(negative regulation of oxidative stress-induced cell death);GO:1903377(negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway);GO:1903599(positive regulation of mitophagy);GO:0006517(protein deglycosylation);GO:0050727(regulation of inflammatory response);GO:0070301(cellular response to hydrogen peroxide);GO:0051444(negative regulation of ubiquitin-protein transferase activity);GO:0031397(negative regulation of protein ubiquitination);GO:0043066(negative regulation of apoptotic process);GO:0032148(activation of protein kinase B activity);GO:0033138(positive regulation of peptidyl-serine phosphorylation);GO:0030424(axon);GO:0060765(regulation of androgen receptor signaling pathway);GO:2000825(positive regulation of androgen receptor activity);GO:1905259(negative regulation of nitrosative stress-induced intrinsic apoptotic signaling pathway);GO:0051881(regulation of mitochondrial membrane potential);GO:0005747(mitochondrial respiratory chain complex I);GO:1903208(negative regulation of hydrogen peroxide-induced neuron death);GO:1903094(negative regulation of protein K48-linked deubiquitination);GO:2000157(negative regulation of ubiquitin-specific protease activity);GO:0010273(detoxification of copper ion);GO:0070491(repressing transcription factor binding);GO:0043523(regulation of neuron apoptotic process);GO:0097110(scaffold protein binding);GO:0001933(negative regulation of protein phosphorylation);GO:0044390(ubiquitin-like protein conjugating enzyme binding);GO:0003713(transcription coactivator activity);GO:0016532(superoxide dismutase copper chaperone activity);GO:0016684(oxidoreductase activity, acting on peroxide as acceptor);GO:0019955(cytokine binding);GO:0036470(tyrosine 3-monooxygenase activator activity);GO:0036478(L-dopa decarboxylase activator activity);GO:0036524(protein deglycase activity);GO:0044388(small protein activating enzyme binding);GO:0045340(mercury ion binding);GO:0050681(androgen receptor binding);GO:1903135(cupric ion binding);GO:1903136(cuprous ion binding);GO:0002866(positive regulation of acute inflammatory response to antigenic stimulus);GO:0006469(negative regulation of protein kinase activity);GO:0007265(Ras protein signal transduction);GO:0009438(methylglyoxal metabolic process);GO:0019249(lactate biosynthetic process);GO:0032435(negative regulation of proteasomal ubiquitin-dependent protein catabolic process);GO:0032757(positive regulation of interleukin-8 production);GO:0033234(negative regulation of protein sumoylation);GO:0033864(positive regulation of NAD(P)H oxidase activity);GO:0036471(cellular response to glyoxal);GO:0036526(peptidyl-cysteine deglycation);GO:0036527(peptidyl-arginine deglycation);GO:0036528(peptidyl-lysine deglycation);GO:0036529(protein deglycation, glyoxal removal);GO:0036530(protein deglycation, methylglyoxal removal);GO:0036531(glutathione deglycation);GO:0042743(hydrogen peroxide metabolic process);GO:0046295(glycolate biosynthetic process);GO:0046826(negative regulation of protein export from nucleus);GO:0050787(detoxification of mercury ion);GO:0090073(positive regulation of protein homodimerization activity);GO:1900182(positive regulation of protein localization to nucleus);GO:1901671(positive regulation of superoxide dismutase activity);GO:1901984(negative regulation of protein acetylation);GO:1902903(regulation of supramolecular fiber organization);GO:1902958(positive regulation of mitochondrial electron transport, NADH to ubiquinone);GO:1903073(negative regulation of death-inducing signaling complex assembly);GO:1903122(negative regulation of TRAIL-activated apoptotic signaling pathway);GO:1903168(positive regulation of pyrroline-5-carboxylate reductase activity);GO:1903178(positive regulation of tyrosine 3-monooxygenase activity);GO:1903181(positive regulation of dopamine biosynthetic process);GO:1903189(glyoxal metabolic process);GO:1903197(positive regulation of L-dopa biosynthetic process);GO:1903200(positive regulation of L-dopa decarboxylase activity);GO:1903384(negative regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway);GO:2000679(positive regulation of transcription regulatory region DNA binding);GO:2001268(negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway);GO:0016605(PML body);GO:0051920(peroxiredoxin activity);GO:0001963(synaptic transmission, dopaminergic);GO:0008344(adult locomotory behavior);GO:0018323(enzyme active site formation via L-cysteine sulfinic acid);GO:0034614(cellular response to reactive oxygen species);GO:0042177(negative regulation of protein catabolic process);GO:0042542(response to hydrogen peroxide);GO:0051583(dopamine uptake involved in synaptic transmission);GO:0051899(membrane depolarization);GO:0060081(membrane hyperpolarization);GO:1902177(positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway);GO:1903204(negative regulation of oxidative stress-induced neuron death);GO:1903428(positive regulation of reactive oxygen species biosynthetic process);GO:2000277(positive regulation of oxidative phosphorylation uncoupler activity);GO:0005758(mitochondrial intermembrane space);GO:0005759(mitochondrial matrix);GO:0005783(endoplasmic reticulum);GO:0043005(neuron projection);GO:0044297(cell body)","05012(Parkinson's disease)","NA","NA","Parkinsonism associated deglycase [Source:HGNC Symbol;Acc:HGNC:16369]",0,0,1,0,1,1,"no","no"]
[140942,0,"chr3","+",138187350,138245635,"ENST00000489213",11,1714,"ENSG00000114098","ARMC8","GO:0005515(protein binding);GO:0005576(extracellular region);GO:0043312(neutrophil degranulation);GO:0035580(specific granule lumen);GO:1904724(tertiary granule lumen)","NA","NA","NA","armadillo repeat containing 8 [Source:HGNC Symbol;Acc:HGNC:24999]",0,{"v":0.208846,"d":"0.21"},"-inf","-inf",1,1,"down","no"]
[40486,0,"chr12","+",42331787,42375026,"ENST00000546750",6,588,"MSTRG.3293","PPHLN1","GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005794(Golgi apparatus);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0005694(chromosome);GO:0005515(protein binding);GO:0031424(keratinization)","NA","NA","NA","periphilin 1 [Source:HGNC Symbol;Acc:HGNC:19369]",{"v":1.304E-3,"d":"0.00"},0,"inf","inf",1,1,"up","no"]
[181530,0,"chr8","-",17234801,17237595,"ENST00000522062",2,444,"MSTRG.14202","CNOT7","GO:0010629(negative regulation of gene expression);GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016607(nuclear speck);GO:0016020(membrane);GO:0046872(metal ion binding);GO:0016787(hydrolase activity);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0090305(nucleic acid phosphodiester bond hydrolysis);GO:0005515(protein binding);GO:0016604(nuclear body);GO:0004527(exonuclease activity);GO:0004518(nuclease activity);GO:0031047(gene silencing by RNA);GO:0051607(defense response to virus);GO:0000932(P-body);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0006977(DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest);GO:0005829(cytosol);GO:0008285(negative regulation of cell proliferation);GO:0004535(poly(A)-specific ribonuclease activity);GO:0000289(nuclear-transcribed mRNA poly(A) tail shortening);GO:0006417(regulation of translation);GO:0060213(positive regulation of nuclear-transcribed mRNA poly(A) tail shortening);GO:0061014(positive regulation of mRNA catabolic process);GO:0090503(RNA phosphodiester bond hydrolysis, exonucleolytic);GO:1900153(positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay);GO:0030014(CCR4-NOT complex);GO:0030015(CCR4-NOT core complex);GO:0008284(positive regulation of cell proliferation);GO:0004871(signal transducer activity);GO:0007165(signal transduction);GO:0008134(transcription factor binding);GO:0005975(carbohydrate metabolic process);GO:0045892(negative regulation of transcription, DNA-templated);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0045070(positive regulation of viral genome replication);GO:0060339(negative regulation of type I interferon-mediated signaling pathway);GO:0035195(gene silencing by miRNA);GO:0004532(exoribonuclease activity);GO:0000175(3'-5'-exoribonuclease activity);GO:0043928(exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay);GO:0001191(transcriptional repressor activity, RNA polymerase II transcription factor binding);GO:0042509(regulation of tyrosine phosphorylation of STAT protein);GO:0000290(deadenylation-dependent decapping of nuclear-transcribed mRNA);GO:0033962(cytoplasmic mRNA processing body assembly);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0075341(host cell PML body)","03018(RNA degradation)","NA","NA","CCR4-NOT transcription complex subunit 7 [Source:HGNC Symbol;Acc:HGNC:14101]",0,0,1,0,1,1,"no","no"]
[77863,0,"chr17","-",3608262,3636322,"ENST00000225519",7,3838,"MSTRG.6303","SHPK","GO:0005737(cytoplasm);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0016773(phosphotransferase activity, alcohol group as acceptor);GO:0005975(carbohydrate metabolic process);GO:0005829(cytosol);GO:0071222(cellular response to lipopolysaccharide);GO:0050727(regulation of inflammatory response);GO:0006098(pentose-phosphate shunt);GO:0043030(regulation of macrophage activation);GO:0035963(cellular response to interleukin-13);GO:0071353(cellular response to interleukin-4);GO:0009052(pentose-phosphate shunt, non-oxidative branch);GO:0050277(sedoheptulokinase activity)","NA","NA","NA","sedoheptulokinase [Source:HGNC Symbol;Acc:HGNC:1492]",{"v":0.605271,"d":"0.61"},0,"inf","inf",1,1,"up","no"]
[188243,0,"chr8","+",144096345,144097176,"ENST00000525122",2,543,"MSTRG.14625","CYC1","GO:0005634(nucleus);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0046872(metal ion binding);GO:0055114(oxidation-reduction process);GO:0005739(mitochondrion);GO:0005743(mitochondrial inner membrane);GO:0070469(respiratory chain);GO:0020037(heme binding);GO:0009055(electron carrier activity);GO:0006122(mitochondrial electron transport, ubiquinol to cytochrome c);GO:0005750(mitochondrial respiratory chain complex III);GO:0045153(electron transporter, transferring electrons within CoQH2-cytochrome c reductase complex activity);GO:0045155(electron transporter, transferring electrons from CoQH2-cytochrome c reductase complex and cytochrome c oxidase complex activity);GO:0033762(response to glucagon);GO:0042776(mitochondrial ATP synthesis coupled proton transport)","00190(Oxidative phosphorylation);04260(Cardiac muscle contraction);05010(Alzheimer's disease);05012(Parkinson's disease);05016(Huntington's disease);04932(Non-alcoholic fatty liver disease (NAFLD))","NA","NA","cytochrome c1 [Source:HGNC Symbol;Acc:HGNC:2579]",{"v":0.144702,"d":"0.14"},{"v":0.007101,"d":"0.01"},{"v":20.3776932826362,"d":"20.38"},{"v":4.34891884521102,"d":"4.35"},1,1,"up","no"]
[16312,0,"chr1","-",223538008,223551017,"ENST00000442247",4,327,"ENSG00000203697","CAPN8","GO:0005509(calcium ion binding);GO:0007586(digestion);GO:0016787(hydrolase activity);GO:0005622(intracellular);GO:0008233(peptidase activity);GO:0008234(cysteine-type peptidase activity);GO:0006508(proteolysis);GO:0004198(calcium-dependent cysteine-type endopeptidase activity);GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0005794(Golgi apparatus)","NA","NA","NA","calpain 8 [Source:HGNC Symbol;Acc:HGNC:1485]",0,{"v":0.18417,"d":"0.18"},"-inf","-inf",1,1,"down","no"]
[194253,0,"chr9","+",131135988,131146193,"ENST00000530863",5,560,"MSTRG.15045","NUP214","GO:0006810(transport);GO:0051028(mRNA transport);GO:0005634(nucleus);GO:0015031(protein transport);GO:0043231(intracellular membrane-bounded organelle);GO:0005925(focal adhesion);GO:0005643(nuclear pore);GO:0005515(protein binding);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0075733(intracellular transport of virus);GO:0043657(host cell);GO:0043488(regulation of mRNA stability);GO:0008139(nuclear localization sequence binding);GO:0006611(protein export from nucleus);GO:0016032(viral process);GO:0006406(mRNA export from nucleus);GO:0016925(protein sumoylation);GO:0006606(protein import into nucleus);GO:0060964(regulation of gene silencing by miRNA);GO:0005049(nuclear export signal receptor activity);GO:0006110(regulation of glycolytic process);GO:0006409(tRNA export from nucleus);GO:0007077(mitotic nuclear envelope disassembly);GO:0019083(viral transcription);GO:1900034(regulation of cellular response to heat);GO:0017056(structural constituent of nuclear pore);GO:0006405(RNA export from nucleus);GO:0005487(nucleocytoplasmic transporter activity);GO:0051726(regulation of cell cycle);GO:0044613(nuclear pore central transport channel);GO:0044615(nuclear pore nuclear basket);GO:1990876(cytoplasmic side of nuclear pore)","03013(RNA transport);05169(Epstein-Barr virus infection)","NA","NA","nucleoporin 214 [Source:HGNC Symbol;Acc:HGNC:8064]",{"v":1.045485,"d":"1.05"},0,"inf","inf",1,1,"up","no"]
[158493,0,"chr5","+",134825813,134829039,"ENST00000506332",2,1589,"MSTRG.12316","DDX46","GO:0003676(nucleic acid binding);GO:0016607(nuclear speck);GO:0005524(ATP binding);GO:0001650(fibrillar center);GO:0003723(RNA binding);GO:0005634(nucleus);GO:0006397(mRNA processing);GO:0008380(RNA splicing);GO:0016020(membrane);GO:0000166(nucleotide binding);GO:0016787(hydrolase activity);GO:0004386(helicase activity);GO:0005737(cytoplasm);GO:0005730(nucleolus);GO:0005654(nucleoplasm);GO:0004004(ATP-dependent RNA helicase activity);GO:0010501(RNA secondary structure unwinding);GO:0000398(mRNA splicing, via spliceosome);GO:0010468(regulation of gene expression);GO:0015030(Cajal body)","03040(Spliceosome)","NA","NA","DEAD-box helicase 46 [Source:HGNC Symbol;Acc:HGNC:18681]",{"v":0.00057,"d":"0.00"},0,"inf","inf",1,1,"up","no"]
[123995,0,"chr20","+",44910062,44930726,"ENST00000217074",8,1263,"MSTRG.9764","PABPC1L","GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0070062(extracellular exosome);GO:0001556(oocyte maturation);GO:0006338(chromatin remodeling);GO:0006378(mRNA polyadenylation);GO:0048096(chromatin-mediated maintenance of transcription);GO:0051647(nucleus localization)","03013(RNA transport);03015(mRNA surveillance pathway);03018(RNA degradation)","NA","NA","poly(A) binding protein cytoplasmic 1 like [Source:HGNC Symbol;Acc:HGNC:15797]",0,0,1,0,1,1,"no","no"]
[139524,0,"chr3","+",119782035,119810552,"ENST00000474090",3,977,"ENSG00000144852","NR1I2","GO:0005634(nucleus);GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0005654(nucleoplasm);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0045111(intermediate filament cytoskeleton);GO:0043565(sequence-specific DNA binding);GO:0003707(steroid hormone receptor activity);GO:0043401(steroid hormone mediated signaling pathway);GO:0030522(intracellular receptor signaling pathway);GO:0004887(thyroid hormone receptor activity);GO:0005515(protein binding);GO:0016604(nuclear body);GO:0045893(positive regulation of transcription, DNA-templated);GO:0006805(xenobiotic metabolic process);GO:0042738(exogenous drug catabolic process);GO:0001228(transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0004879(RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding);GO:0010628(positive regulation of gene expression);GO:0003713(transcription coactivator activity);GO:0007165(signal transduction);GO:0006367(transcription initiation from RNA polymerase II promoter);GO:0008144(drug binding);GO:0000977(RNA polymerase II regulatory region sequence-specific DNA binding);GO:0008202(steroid metabolic process);GO:0042908(xenobiotic transport);GO:0045892(negative regulation of transcription, DNA-templated);GO:0046618(drug export)","NA","NA","NA","nuclear receptor subfamily 1 group I member 2 [Source:HGNC Symbol;Acc:HGNC:7968]",0,{"v":0.291743,"d":"0.29"},"-inf","-inf",1,1,"down","no"]
[3899,0,"chr1","+",32465057,32600792,"ENST00000480336",10,3447,"MSTRG.380","AL033529.1","NA","NA","NA","NA","NA",0,0,1,0,1,1,"no","no"]
[31426,0,"chr11","+",65860545,65863089,"ENST00000525768",6,923,"MSTRG.2571","MUS81","GO:0003677(DNA binding);GO:0090305(nucleic acid phosphodiester bond hydrolysis);GO:0004518(nuclease activity);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0016787(hydrolase activity);GO:0005515(protein binding);GO:0006281(DNA repair);GO:0006310(DNA recombination);GO:0006974(cellular response to DNA damage stimulus);GO:0004519(endonuclease activity);GO:0005730(nucleolus);GO:0000712(resolution of meiotic recombination intermediates);GO:0031297(replication fork processing);GO:0005654(nucleoplasm);GO:0008821(crossover junction endodeoxyribonuclease activity);GO:0031573(intra-S DNA damage checkpoint);GO:0048476(Holliday junction resolvase complex);GO:0036297(interstrand cross-link repair);GO:0000727(double-strand break repair via break-induced replication);GO:0004520(endodeoxyribonuclease activity);GO:0048257(3'-flap endonuclease activity);GO:0072429(response to intra-S DNA damage checkpoint signaling);GO:0000737(DNA catabolic process, endonucleolytic);GO:0007095(mitotic G2 DNA damage checkpoint)","03440(Homologous recombination);03460(Fanconi anemia pathway)","NA","NA","MUS81 structure-specific endonuclease subunit [Source:HGNC Symbol;Acc:HGNC:29814]",{"v":0.325672,"d":"0.33"},{"v":0.02313,"d":"0.02"},{"v":14.0800691742326,"d":"14.08"},{"v":3.81558251672317,"d":"3.82"},1,1,"up","no"]
[154553,0,"chr5","+",43042133,43045268,"ENST00000508913",2,2311,"ENSG00000215068","AC025171.2","NA","NA","NA","NA","NA",{"v":0.073445,"d":"0.07"},{"v":0.043614,"d":"0.04"},{"v":1.68397762186454,"d":"1.68"},{"v":0.751872966765611,"d":"0.75"},1,1,"up","no"]
[19523,0,"chr10","-",32345392,32347121,"ENST00000469059",2,591,"MSTRG.1647","EPC1","GO:0005634(nucleus);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0016569(covalent chromatin modification);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0005515(protein binding);GO:0004402(histone acetyltransferase activity);GO:0045893(positive regulation of transcription, DNA-templated);GO:0005654(nucleoplasm);GO:0040008(regulation of growth);GO:0032777(Piccolo NuA4 histone acetyltransferase complex);GO:0035267(NuA4 histone acetyltransferase complex);GO:0043967(histone H4 acetylation);GO:0045892(negative regulation of transcription, DNA-templated);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0043968(histone H2A acetylation);GO:0045814(negative regulation of gene expression, epigenetic);GO:0031965(nuclear membrane);GO:0035886(vascular smooth muscle cell differentiation)","NA","NA","NA","enhancer of polycomb homolog 1 [Source:HGNC Symbol;Acc:HGNC:19876]",{"v":0.062666,"d":"0.06"},0,"inf","inf",1,1,"up","no"]
[132511,0,"chr22","-",50281127,50282006,"ENST00000492578",3,644,"MSTRG.10594","PLXNB2","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0007165(signal transduction);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0007275(multicellular organism development);GO:0017154(semaphorin receptor activity);GO:0071526(semaphorin-plexin signaling pathway);GO:0005887(integral component of plasma membrane);GO:0070062(extracellular exosome);GO:0008360(regulation of cell shape);GO:0043087(regulation of GTPase activity);GO:0009986(cell surface);GO:0007405(neuroblast proliferation);GO:0007420(brain development);GO:0001843(neural tube closure);GO:0001932(regulation of protein phosphorylation);GO:0007156(homophilic cell adhesion via plasma membrane adhesion molecules);GO:0007162(negative regulation of cell adhesion);GO:0010976(positive regulation of neuron projection development);GO:0050772(positive regulation of axonogenesis);GO:2001222(regulation of neuron migration)","04360(Axon guidance)","NA","NA","plexin B2 [Source:HGNC Symbol;Acc:HGNC:9104]",{"v":0.116009,"d":"0.12"},{"v":0.292852,"d":"0.29"},{"v":0.396135249204376,"d":"0.40"},{"v":-1.33593501295883,"d":"-1.34"},1,1,"down","no"]
[133421,0,"chr3","-",11807294,11846779,"ENST00000444133",7,1619,"ENSG00000144559","TAMM41","GO:0016020(membrane);GO:0016740(transferase activity);GO:0005743(mitochondrial inner membrane);GO:0006629(lipid metabolic process);GO:0005739(mitochondrion);GO:0008654(phospholipid biosynthetic process);GO:0016779(nucleotidyltransferase activity);GO:0032049(cardiolipin biosynthetic process);GO:0004605(phosphatidate cytidylyltransferase activity);GO:0016024(CDP-diacylglycerol biosynthetic process);GO:0031314(extrinsic component of mitochondrial inner membrane)","NA","NA","NA","TAM41 mitochondrial translocator assembly and maintenance homolog [Source:HGNC Symbol;Acc:HGNC:25187]",{"v":0.095248,"d":"0.10"},{"v":0.056361,"d":"0.06"},{"v":1.68996291762034,"d":"1.69"},{"v":0.75699159020439,"d":"0.76"},1,1,"up","no"]
[153044,0,"chr5","+",461630,464728,"ENST00000511015",3,1031,"MSTRG.11953","EXOC3","GO:0006810(transport);GO:0005737(cytoplasm);GO:0015031(protein transport);GO:0006887(exocytosis);GO:0000145(exocyst);GO:0005794(Golgi apparatus);GO:0042995(cell projection);GO:0048471(perinuclear region of cytoplasm);GO:0030496(midbody);GO:0005515(protein binding);GO:0005829(cytosol);GO:0045296(cadherin binding);GO:0030426(growth cone);GO:0000149(SNARE binding);GO:0030667(secretory granule membrane);GO:0051601(exocyst localization)","NA","NA","NA","exocyst complex component 3 [Source:HGNC Symbol;Acc:HGNC:30378]",{"v":0.72469,"d":"0.72"},{"v":0.40418,"d":"0.40"},{"v":1.79298827255183,"d":"1.79"},{"v":0.842366051961645,"d":"0.84"},1,1,"up","no"]
[201343,0,"chrX","+",154547642,154565033,"ENST00000611176",8,1654,"MSTRG.15518","IKBKG","GO:0005829(cytosol);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0042803(protein homodimerization activity);GO:0005515(protein binding);GO:0006974(cellular response to DNA damage stimulus);GO:0045087(innate immune response);GO:0006954(inflammatory response);GO:0000922(spindle pole);GO:0038095(Fc-epsilon receptor signaling pathway);GO:0031593(polyubiquitin binding);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0002223(stimulatory C-type lectin receptor signaling pathway);GO:0002479(antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent);GO:0016579(protein deubiquitination);GO:0050852(T cell receptor signaling pathway);GO:0009615(response to virus);GO:0016032(viral process);GO:0004871(signal transducer activity);GO:0006955(immune response);GO:0051092(positive regulation of NF-kappaB transcription factor activity);GO:0019904(protein domain specific binding);GO:0006915(apoptotic process);GO:0007249(I-kappaB kinase/NF-kappaB signaling);GO:0035666(TRIF-dependent toll-like receptor signaling pathway);GO:0046982(protein heterodimerization activity);GO:0016239(positive regulation of macroautophagy);GO:0007254(JNK cascade);GO:0010803(regulation of tumor necrosis factor-mediated signaling pathway);GO:0043123(positive regulation of I-kappaB kinase/NF-kappaB signaling);GO:0051403(stress-activated MAPK cascade);GO:0070423(nucleotide-binding oligomerization domain containing signaling pathway);GO:0008385(IkappaB kinase complex);GO:0005622(intracellular);GO:0031625(ubiquitin protein ligase binding);GO:0000151(ubiquitin ligase complex);GO:0000187(activation of MAPK activity);GO:0043276(anoikis);GO:1901215(negative regulation of neuron death);GO:0072686(mitotic spindle);GO:0070530(K63-linked polyubiquitin binding);GO:0051650(establishment of vesicle localization);GO:0042975(peroxisome proliferator activated receptor binding);GO:1990450(linear polyubiquitin binding)","04014(Ras signaling pathway);04010(MAPK signaling pathway);04064(NF-kappa B signaling pathway);04668(TNF signaling pathway);04151(PI3K-Akt signaling pathway);04210(Apoptosis);04620(Toll-like receptor signaling pathway);04621(NOD-like receptor signaling pathway);04622(RIG-I-like receptor signaling pathway);04623(Cytosolic DNA-sensing pathway);04660(T cell receptor signaling pathway);04658(Th1 and Th2 cell differentiation);04659(Th17 cell differentiation);04657(IL-17 signaling pathway);04662(B cell receptor signaling pathway);04062(Chemokine signaling pathway);04920(Adipocytokine signaling pathway);04380(Osteoclast differentiation);05200(Pathways in cancer);05203(Viral carcinogenesis);05212(Pancreatic cancer);05221(Acute myeloid leukemia);05220(Chronic myeloid leukemia);05215(Prostate cancer);05222(Small cell lung cancer);05340(Primary immunodeficiency);05418(Fluid shear stress and atherosclerosis);05120(Epithelial cell signaling in Helicobacter pylori infection);05131(Shigellosis);05166(HTLV-I infection);05161(Hepatitis B);05160(Hepatitis C);05168(Herpes simplex infection);05167(Kaposi's sarcoma-associated herpesvirus infection);05169(Epstein-Barr virus infection);05165(Human papillomavirus infection);05145(Toxoplasmosis);05142(Chagas disease (American trypanosomiasis));01523(Antifolate resistance)","K07210","NA","inhibitor of nuclear factor kappa B kinase subunit gamma [Source:HGNC Symbol;Acc:HGNC:5961]",0,{"v":0.298645,"d":"0.30"},"-inf","-inf",1,1,"down","no"]
[3041,0,"chr1","+",26234202,26278808,"ENST00000252992",14,3935,"MSTRG.276","CEP85","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005794(Golgi apparatus);GO:0005730(nucleolus);GO:0005829(cytosol);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0000922(spindle pole);GO:0005813(centrosome);GO:0005815(microtubule organizing center);GO:0007059(chromosome segregation);GO:0006469(negative regulation of protein kinase activity);GO:0046602(regulation of mitotic centrosome separation);GO:0000242(pericentriolar material)","NA","NA","NA","centrosomal protein 85 [Source:HGNC Symbol;Acc:HGNC:25309]",{"v":0.096287,"d":"0.10"},{"v":0.933584,"d":"0.93"},{"v":0.103136943220964,"d":"0.10"},{"v":-3.2773669022879,"d":"-3.28"},1,1,"down","no"]
[30524,0,"chr11","-",63574474,63598715,"ENST00000639271",4,957,"ENSG00000176485","PLA2G16","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016787(hydrolase activity);GO:0006629(lipid metabolic process);GO:0016042(lipid catabolic process);GO:0005515(protein binding);GO:0048471(perinuclear region of cytoplasm);GO:0004623(phospholipase A2 activity);GO:0008970(phosphatidylcholine 1-acylhydrolase activity);GO:0006641(triglyceride metabolic process);GO:0007031(peroxisome organization);GO:0008654(phospholipid biosynthetic process);GO:0045786(negative regulation of cell cycle);GO:0046485(ether lipid metabolic process);GO:1904177(regulation of adipose tissue development);GO:0005777(peroxisome);GO:0005783(endoplasmic reticulum);GO:0005778(peroxisomal membrane);GO:0005575(cellular_component);GO:0005829(cytosol);GO:0006644(phospholipid metabolic process);GO:0036149(phosphatidylinositol acyl-chain remodeling);GO:0036150(phosphatidylserine acyl-chain remodeling);GO:0036151(phosphatidylcholine acyl-chain remodeling);GO:0036152(phosphatidylethanolamine acyl-chain remodeling);GO:0016746(transferase activity, transferring acyl groups);GO:0052739(phosphatidylserine 1-acylhydrolase activity);GO:0052740(1-acyl-2-lysophosphatidylserine acylhydrolase activity)","00564(Glycerophospholipid metabolism);00565(Ether lipid metabolism);00590(Arachidonic acid metabolism);00591(Linoleic acid metabolism);00592(alpha-Linolenic acid metabolism);04014(Ras signaling pathway);04923(Regulation of lipolysis in adipocyte)","NA","NA","phospholipase A2 group XVI [Source:HGNC Symbol;Acc:HGNC:17825]",0,{"v":0.004821,"d":"0.00"},"-inf","-inf",1,1,"down","no"]
[52281,0,"chr14","-",20311704,20333303,"ENST00000556854",8,1294,"MSTRG.4126","CCNB1IP1","GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0016740(transferase activity);GO:0016567(protein ubiquitination);GO:0005694(chromosome);GO:0005515(protein binding);GO:0051321(meiotic cell cycle);GO:0061630(ubiquitin protein ligase activity);GO:0007131(reciprocal meiotic recombination);GO:0000795(synaptonemal complex);GO:0051026(chiasma assembly);GO:0001825(blastocyst formation);GO:0007286(spermatid development);GO:0000794(condensed nuclear chromosome)","NA","NA","NA","cyclin B1 interacting protein 1 [Source:HGNC Symbol;Acc:HGNC:19437]",0,0,1,0,1,1,"no","no"]
[13250,0,"chr1","-",165754893,165768922,"ENST00000628579",4,477,"ENSG00000143183","TMCO1","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005783(endoplasmic reticulum);GO:0005794(Golgi apparatus);GO:0005789(endoplasmic reticulum membrane);GO:0006811(ion transport);GO:0000139(Golgi membrane);GO:0006816(calcium ion transport);GO:0005262(calcium channel activity);GO:0070588(calcium ion transmembrane transport);GO:0030176(integral component of endoplasmic reticulum membrane);GO:0032469(endoplasmic reticulum calcium ion homeostasis);GO:0006983(ER overload response)","NA","NA","NA","transmembrane and coiled-coil domains 1 [Source:HGNC Symbol;Acc:HGNC:18188]",{"v":0.134746,"d":"0.13"},{"v":0.157258,"d":"0.16"},{"v":0.856846710501215,"d":"0.86"},{"v":-0.222890964972408,"d":"-0.22"},1,1,"down","no"]
[94681,0,"chr19","-",2717769,2740048,"ENST00000586572",3,543,"MSTRG.7645","AC006538.2","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0055085(transmembrane transport);GO:0046873(metal ion transmembrane transporter activity);GO:0030001(metal ion transport);GO:0005385(zinc ion transmembrane transporter activity);GO:0071577(zinc II ion transmembrane transport)","NA","NA","NA","NA",{"v":1.634E-3,"d":"0.00"},0,"inf","inf",1,1,"up","no"]
[147618,0,"chr4","+",56474134,56491565,"ENST00000505314",12,1071,"MSTRG.11636","SRP72","GO:0003723(RNA binding);GO:0005737(cytoplasm);GO:0030529(intracellular ribonucleoprotein complex);GO:0005783(endoplasmic reticulum);GO:0008312(7S RNA binding);GO:0006614(SRP-dependent cotranslational protein targeting to membrane);GO:0048500(signal recognition particle);GO:0005829(cytosol);GO:0006616(SRP-dependent cotranslational protein targeting to membrane, translocation);GO:0005515(protein binding);GO:0005786(signal recognition particle, endoplasmic reticulum targeting);GO:0043022(ribosome binding);GO:0005047(signal recognition particle binding);GO:0030911(TPR domain binding);GO:0042493(response to drug);GO:0005622(intracellular)","03060(Protein export)","NA","NA","signal recognition particle 72 [Source:HGNC Symbol;Acc:HGNC:11303]",0,0,1,0,1,1,"no","no"]
[116116,0,"chr2","+",169733846,169751888,"ENST00000392647",4,4077,"ENSG00000213160","KLHL23","GO:0016567(protein ubiquitination);GO:0005515(protein binding);GO:0004842(ubiquitin-protein transferase activity);GO:0031463(Cul3-RING ubiquitin ligase complex)","NA","NA","NA","kelch like family member 23 [Source:HGNC Symbol;Acc:HGNC:27506]",0,{"v":0.067784,"d":"0.07"},"-inf","-inf",1,1,"down","no"]
[88519,0,"chr17","+",76726843,76733866,"ENST00000586738",6,1059,"MSTRG.7259","METTL23","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0008168(methyltransferase activity);GO:0016740(transferase activity);GO:0032259(methylation);GO:0005515(protein binding);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0043234(protein complex);GO:0008134(transcription factor binding);GO:0050890(cognition);GO:0031072(heat shock protein binding)","NA","NA","NA","methyltransferase like 23 [Source:HGNC Symbol;Acc:HGNC:26988]",0,{"v":0.005109,"d":"0.01"},"-inf","-inf",1,1,"down","no"]
[114910,0,"chr2","+",143706411,143768348,"ENST00000549060",2,537,"MSTRG.9139","ARHGAP15","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0007165(signal transduction);GO:0043547(positive regulation of GTPase activity);GO:0005096(GTPase activator activity);GO:0005829(cytosol);GO:0051056(regulation of small GTPase mediated signal transduction);GO:0008360(regulation of cell shape)","NA","NA","NA","Rho GTPase activating protein 15 [Source:HGNC Symbol;Acc:HGNC:21030]",{"v":0.064479,"d":"0.06"},{"v":0.171621,"d":"0.17"},{"v":0.375705770272869,"d":"0.38"},{"v":-1.41232482112188,"d":"-1.41"},1,1,"down","no"]
[105487,0,"chr19","-",54356286,54357629,"ENST00000460312",3,944,"ENSG00000167613","LAIR1","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0002376(immune system process);GO:0002250(adaptive immune response);GO:0050776(regulation of immune response);GO:0070062(extracellular exosome);GO:0043312(neutrophil degranulation);GO:0035579(specific granule membrane);GO:0070821(tertiary granule membrane)","NA","NA","NA","leukocyte associated immunoglobulin like receptor 1 [Source:HGNC Symbol;Acc:HGNC:6477]",0,0,1,0,1,1,"no","no"]
[185837,0,"chr8","+",97887834,97931106,"ENST00000520160",2,563,"MSTRG.14476","MATN2","GO:0005509(calcium ion binding);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0005578(proteinaceous extracellular matrix);GO:0003674(molecular_function);GO:0008150(biological_process);GO:0031012(extracellular matrix);GO:0001764(neuron migration);GO:0007411(axon guidance);GO:0008347(glial cell migration);GO:0031104(dendrite regeneration);GO:0031175(neuron projection development);GO:0048678(response to axon injury);GO:0005604(basement membrane);GO:0005615(extracellular space)","NA","NA","NA","matrilin 2 [Source:HGNC Symbol;Acc:HGNC:6908]",0,{"v":0.162074,"d":"0.16"},"-inf","-inf",1,1,"down","no"]
[113850,0,"chr2","+",117815058,117824599,"ENST00000474694",9,1083,"MSTRG.9069","DDX18","GO:0003676(nucleic acid binding);GO:0005524(ATP binding);GO:0003723(RNA binding);GO:0005634(nucleus);GO:0016020(membrane);GO:0000166(nucleotide binding);GO:0005730(nucleolus);GO:0016787(hydrolase activity);GO:0004386(helicase activity);GO:0005694(chromosome);GO:0071392(cellular response to estradiol stimulus);GO:0005737(cytoplasm);GO:0005515(protein binding);GO:0010501(RNA secondary structure unwinding);GO:0004004(ATP-dependent RNA helicase activity)","NA","NA","NA","DEAD-box helicase 18 [Source:HGNC Symbol;Acc:HGNC:2741]",{"v":0.011075,"d":"0.01"},0,"inf","inf",1,1,"up","no"]
[140265,0,"chr3","+",128879596,128884689,"ENST00000505602",2,553,"ENSG00000177646","ACAD9","GO:0005634(nucleus);GO:0016491(oxidoreductase activity);GO:0050660(flavin adenine dinucleotide binding);GO:0055114(oxidation-reduction process);GO:0016627(oxidoreductase activity, acting on the CH-CH group of donors);GO:0005739(mitochondrion);GO:0008152(metabolic process);GO:0003995(acyl-CoA dehydrogenase activity);GO:0030425(dendrite);GO:0005515(protein binding);GO:0032981(mitochondrial respiratory chain complex I assembly);GO:0005743(mitochondrial inner membrane)","NA","NA","NA","acyl-CoA dehydrogenase family member 9 [Source:HGNC Symbol;Acc:HGNC:21497]",0,{"v":0.052212,"d":"0.05"},"-inf","-inf",1,1,"down","no"]
[198839,0,"chrX","-",101349447,101386224,"ENST00000372880",17,2248,"MSTRG.15389","BTK","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0035556(intracellular signal transduction);GO:0004713(protein tyrosine kinase activity);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0004715(non-membrane spanning protein tyrosine kinase activity);GO:0006915(apoptotic process);GO:0002376(immune system process);GO:0045087(innate immune response);GO:0002250(adaptive immune response);GO:0038095(Fc-epsilon receptor signaling pathway);GO:0042802(identical protein binding);GO:0042629(mast cell granule);GO:0008289(lipid binding);GO:0005547(phosphatidylinositol-3,4,5-trisphosphate binding);GO:0042113(B cell activation);GO:0051092(positive regulation of NF-kappaB transcription factor activity);GO:0002755(MyD88-dependent toll-like receptor signaling pathway);GO:0042127(regulation of cell proliferation);GO:0050853(B cell receptor signaling pathway);GO:0005102(receptor binding);GO:0007498(mesoderm development);GO:0019722(calcium-mediated signaling);GO:0045121(membrane raft);GO:0038083(peptidyl-tyrosine autophosphorylation);GO:0031234(extrinsic component of cytoplasmic side of plasma membrane);GO:0097190(apoptotic signaling pathway);GO:0007169(transmembrane receptor protein tyrosine kinase signaling pathway);GO:0045579(positive regulation of B cell differentiation);GO:0002721(regulation of B cell cytokine production);GO:0002902(regulation of B cell apoptotic process);GO:0018108(peptidyl-tyrosine phosphorylation);GO:0001805(positive regulation of type III hypersensitivity);GO:0001812(positive regulation of type I hypersensitivity);GO:0001818(negative regulation of cytokine production);GO:0002344(B cell affinity maturation);GO:0002553(histamine secretion by mast cell);GO:0007249(I-kappaB kinase/NF-kappaB signaling);GO:0010033(response to organic substance);GO:0030889(negative regulation of B cell proliferation);GO:0034614(cellular response to reactive oxygen species);GO:0046777(protein autophosphorylation);GO:0048469(cell maturation);GO:0071226(cellular response to molecule of fungal origin);GO:0098761(cellular response to interleukin-7);GO:0031410(cytoplasmic vesicle);GO:0048471(perinuclear region of cytoplasm);GO:0005622(intracellular)","04064(NF-kappa B signaling pathway);04611(Platelet activation);04662(B cell receptor signaling pathway);04664(Fc epsilon RI signaling pathway);04380(Osteoclast differentiation);05340(Primary immunodeficiency)","K07370","EC:2.7.10.2","Bruton tyrosine kinase [Source:HGNC Symbol;Acc:HGNC:1133]",{"v":0.000138,"d":"0.00"},{"v":0.024439,"d":"0.02"},{"v":0.00564671222226769,"d":"0.01"},{"v":-7.46837317664491,"d":"-7.47"},1,1,"down","no"]
[167769,0,"chr6","-",89377705,89411505,"ENST00000492783",5,892,"ENSG00000025039","RRAGD","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005525(GTP binding);GO:0000166(nucleotide binding);GO:0005654(nucleoplasm);GO:0005813(centrosome);GO:0005515(protein binding);GO:0005764(lysosome);GO:0034448(EGO complex);GO:0071230(cellular response to amino acid stimulus);GO:0005829(cytosol);GO:0046982(protein heterodimerization activity);GO:0032008(positive regulation of TOR signaling);GO:0003924(GTPase activity);GO:0007050(cell cycle arrest);GO:0016241(regulation of macroautophagy);GO:0010506(regulation of autophagy);GO:0019003(GDP binding);GO:0034613(cellular protein localization);GO:0071233(cellular response to leucine);GO:1990253(cellular response to leucine starvation);GO:0051020(GTPase binding);GO:1904263(positive regulation of TORC1 signaling);GO:1990131(Gtr1-Gtr2 GTPase complex)","04150(mTOR signaling pathway);04140(Autophagy - animal)","NA","NA","Ras related GTP binding D [Source:HGNC Symbol;Acc:HGNC:19903]",0,0,1,0,1,1,"no","no"]
[200188,0,"chrX","-",135759846,135764444,"ENST00000597510",4,1076,"ENSG00000269096","CT45A3","GO:0005515(protein binding)","NA","NA","NA","cancer/testis antigen family 45 member A3 [Source:HGNC Symbol;Acc:HGNC:33268]",{"v":0.028281,"d":"0.03"},{"v":3.986E-3,"d":"0.00"},{"v":7.09508278976417,"d":"7.10"},{"v":2.8268195186319,"d":"2.83"},1,1,"up","no"]
[105812,0,"chr19","-",55226748,55229264,"ENST00000327042",3,1637,"MSTRG.8436","TMEM86B","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016787(hydrolase activity);GO:0005515(protein binding);GO:0005789(endoplasmic reticulum membrane);GO:0036151(phosphatidylcholine acyl-chain remodeling);GO:0046485(ether lipid metabolic process);GO:0016803(ether hydrolase activity);GO:0047408(alkenylglycerophosphocholine hydrolase activity);GO:0047409(alkenylglycerophosphoethanolamine hydrolase activity)","00565(Ether lipid metabolism)","K18575","EC:3.3.2.2","transmembrane protein 86B [Source:HGNC Symbol;Acc:HGNC:28448]",{"v":0.024189,"d":"0.02"},0,"inf","inf",1,1,"up","no"]
[48402,0,"chr12","+",129013336,129016663,"ENST00000540920",2,2655,"ENSG00000256581","NLRP9P1","NA","NA","NA","NA","NLR family pyrin domain containing 9 pseudogene 1 [Source:HGNC Symbol;Acc:HGNC:29888]",{"v":0.036591,"d":"0.04"},{"v":0.085233,"d":"0.09"},{"v":0.429305550666995,"d":"0.43"},{"v":-1.21992326878698,"d":"-1.22"},1,1,"down","no"]
[1544,0,"chr1","-",11278616,11279351,"ENST00000433562",2,437,"MSTRG.155","UBE2V2P3","NA","NA","NA","NA","ubiquitin conjugating enzyme E2 V2 pseudogene 3 [Source:HGNC Symbol;Acc:HGNC:44891]",0,0,1,0,1,1,"no","no"]
[140155,0,"chr3","+",127599479,127621829,"ENST00000477668",14,2510,"ENSG00000073111","MCM2","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0016787(hydrolase activity);GO:0003677(DNA binding);GO:0004386(helicase activity);GO:0015630(microtubule cytoskeleton);GO:0005515(protein binding);GO:0006270(DNA replication initiation);GO:0007049(cell cycle);GO:0006915(apoptotic process);GO:0006260(DNA replication);GO:0003678(DNA helicase activity);GO:0042555(MCM complex);GO:0000784(nuclear chromosome, telomeric region);GO:0000785(chromatin);GO:0000082(G1/S transition of mitotic cell cycle);GO:0003688(DNA replication origin binding);GO:0019899(enzyme binding);GO:0042393(histone binding);GO:0006268(DNA unwinding involved in DNA replication);GO:0006334(nucleosome assembly);GO:0071353(cellular response to interleukin-4);GO:0090102(cochlea development);GO:0005664(nuclear origin of replication recognition complex);GO:0032508(DNA duplex unwinding)","03030(DNA replication);04110(Cell cycle)","NA","NA","minichromosome maintenance complex component 2 [Source:HGNC Symbol;Acc:HGNC:6944]",0,0,1,0,1,1,"no","no"]
[71447,0,"chr16","-",28989140,28990778,"ENST00000561471",2,454,"MSTRG.5788","AC109460.4","NA","NA","NA","NA","NA",{"v":0.134773,"d":"0.13"},0,"inf","inf",1,1,"up","no"]
[90158,0,"chr18","-",687673,712650,"ENST00000585004",8,1501,"ENSG00000132199","ENOSF1","GO:0046872(metal ion binding);GO:0016853(isomerase activity);GO:0016829(lyase activity);GO:0005739(mitochondrion);GO:0000287(magnesium ion binding);GO:0005575(cellular_component);GO:0050023(L-fuconate dehydratase activity);GO:0009063(cellular amino acid catabolic process);GO:0016052(carbohydrate catabolic process);GO:0044275(cellular carbohydrate catabolic process)","00051(Fructose and mannose metabolism)","NA","NA","enolase superfamily member 1 [Source:HGNC Symbol;Acc:HGNC:30365]",{"v":7.633E-3,"d":"0.01"},0,"inf","inf",1,1,"up","no"]
[87015,0,"chr17","-",64503995,64505527,"ENST00000583239",4,474,"MSTRG.7113","DDX5","GO:0030509(BMP signaling pathway);GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0006397(mRNA processing);GO:0008380(RNA splicing);GO:0005634(nucleus);GO:0016020(membrane);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0016787(hydrolase activity);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0004386(helicase activity);GO:0005515(protein binding);GO:0005681(spliceosomal complex);GO:0048511(rhythmic process);GO:0003713(transcription coactivator activity);GO:0005730(nucleolus);GO:0005737(cytoplasm);GO:0003724(RNA helicase activity);GO:0000956(nuclear-transcribed mRNA catabolic process);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0005654(nucleoplasm);GO:0070062(extracellular exosome);GO:0004004(ATP-dependent RNA helicase activity);GO:0010501(RNA secondary structure unwinding);GO:0030331(estrogen receptor binding);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0031012(extracellular matrix);GO:0043021(ribonucleoprotein complex binding);GO:0000398(mRNA splicing, via spliceosome);GO:0070412(R-SMAD binding);GO:0000381(regulation of alternative mRNA splicing, via spliceosome);GO:0003730(mRNA 3'-UTR binding);GO:0030521(androgen receptor signaling pathway);GO:0030520(intracellular estrogen receptor signaling pathway);GO:0033148(positive regulation of intracellular estrogen receptor signaling pathway);GO:0030529(intracellular ribonucleoprotein complex);GO:0046332(SMAD binding);GO:0071141(SMAD protein complex);GO:0016049(cell growth);GO:0072332(intrinsic apoptotic signaling pathway by p53 class mediator);GO:0071013(catalytic step 2 spliceosome);GO:0050681(androgen receptor binding);GO:0043517(positive regulation of DNA damage response, signal transduction by p53 class mediator);GO:1990841(promoter-specific chromatin binding);GO:0000380(alternative mRNA splicing, via spliceosome);GO:0036002(pre-mRNA binding);GO:0001837(epithelial to mesenchymal transition);GO:1903800(positive regulation of production of miRNAs involved in gene silencing by miRNA);GO:0045445(myoblast differentiation);GO:0070878(primary miRNA binding);GO:0045667(regulation of osteoblast differentiation);GO:0005516(calmodulin binding);GO:0019899(enzyme binding);GO:0035500(MH2 domain binding);GO:0048306(calcium-dependent protein binding);GO:0009299(mRNA transcription);GO:0045069(regulation of viral genome replication);GO:0060765(regulation of androgen receptor signaling pathway);GO:0061614(pri-miRNA transcription from RNA polymerase II promoter);GO:2001014(regulation of skeletal muscle cell differentiation)","03040(Spliceosome);05202(Transcriptional misregulation in cancers);05205(Proteoglycans in cancer)","NA","NA","DEAD-box helicase 5 [Source:HGNC Symbol;Acc:HGNC:2746]",{"v":1.12E-4,"d":"0.00"},{"v":0.033668,"d":"0.03"},{"v":0.00332660092669597,"d":"0.00"},{"v":-8.231735479941,"d":"-8.23"},1,1,"down","no"]
[145105,0,"chr4","-",1056254,1081957,"ENST00000514757",6,991,"ENSG00000178222","RNF212","GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0005694(chromosome);GO:0016874(ligase activity);GO:0051321(meiotic cell cycle);GO:0007131(reciprocal meiotic recombination);GO:0019789(SUMO transferase activity);GO:0007129(synapsis);GO:0016925(protein sumoylation);GO:0000795(synaptonemal complex);GO:0006311(meiotic gene conversion);GO:0051026(chiasma assembly)","NA","NA","NA","ring finger protein 212 [Source:HGNC Symbol;Acc:HGNC:27729]",0,{"v":0.027329,"d":"0.03"},"-inf","-inf",1,1,"down","no"]
[88982,0,"chr17","+",79735541,79739568,"ENST00000576512",3,2002,"ENSG00000182156","ENPP7","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016787(hydrolase activity);GO:0003824(catalytic activity);GO:0005794(Golgi apparatus);GO:0008152(metabolic process);GO:0005886(plasma membrane);GO:0006687(glycosphingolipid metabolic process);GO:0008285(negative regulation of cell proliferation);GO:0005902(microvillus);GO:0004767(sphingomyelin phosphodiesterase activity);GO:0006685(sphingomyelin catabolic process);GO:0008156(negative regulation of DNA replication);GO:0006684(sphingomyelin metabolic process)","00600(Sphingolipid metabolism)","NA","NA","ectonucleotide pyrophosphatase/phosphodiesterase 7 [Source:HGNC Symbol;Acc:HGNC:23764]",{"v":0.025675,"d":"0.03"},0,"inf","inf",1,1,"up","no"]
[114430,0,"chr2","-",130416755,130427986,"ENST00000424873",4,2070,"ENSG00000178162","FAR2P2","NA","NA","NA","NA","fatty acyl-CoA reductase 2 pseudogene 2 [Source:HGNC Symbol;Acc:HGNC:49279]",{"v":0.401507,"d":"0.40"},0,"inf","inf",1,1,"up","no"]
[100187,0,"chr19","+",35612752,35623557,"ENST00000585968",18,2762,"ENSG00000249115","HAUS5","GO:0005737(cytoplasm);GO:0051301(cell division);GO:0005856(cytoskeleton);GO:0007049(cell cycle);GO:0005874(microtubule);GO:0007098(centrosome cycle);GO:0051225(spindle assembly);GO:0070652(HAUS complex);GO:0005813(centrosome);GO:0005815(microtubule organizing center);GO:0005819(spindle);GO:0003674(molecular_function);GO:0005829(cytosol);GO:0000086(G2/M transition of mitotic cell cycle);GO:0010389(regulation of G2/M transition of mitotic cell cycle);GO:0097711(ciliary basal body docking)","NA","NA","NA","HAUS augmin like complex subunit 5 [Source:HGNC Symbol;Acc:HGNC:29130]",0,{"v":0.811885,"d":"0.81"},"-inf","-inf",1,1,"down","no"]
[161935,0,"chr5","-",179621011,179623712,"ENST00000505087",3,592,"MSTRG.12597","HNRNPH1","GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0006397(mRNA processing);GO:0008380(RNA splicing);GO:0005634(nucleus);GO:0016020(membrane);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0030529(intracellular ribonucleoprotein complex);GO:0005681(spliceosomal complex);GO:0005515(protein binding);GO:0043484(regulation of RNA splicing);GO:0000398(mRNA splicing, via spliceosome);GO:0008543(fibroblast growth factor receptor signaling pathway);GO:0016070(RNA metabolic process);GO:0006396(RNA processing);GO:0071013(catalytic step 2 spliceosome);GO:0008266(poly(U) RNA binding)","NA","NA","NA","heterogeneous nuclear ribonucleoprotein H1 [Source:HGNC Symbol;Acc:HGNC:5041]",{"v":3.017764,"d":"3.02"},{"v":0.263719,"d":"0.26"},{"v":11.4431042131966,"d":"11.44"},{"v":3.51640656531565,"d":"3.52"},1,1,"up","no"]
[171849,0,"chr7","-",8156557,8262612,"ENST00000407906",8,1615,"ENSG00000003147","ICA1","GO:0006810(transport);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0043231(intracellular membrane-bounded organelle);GO:0005829(cytosol);GO:0005794(Golgi apparatus);GO:0019904(protein domain specific binding);GO:0005515(protein binding);GO:0000139(Golgi membrane);GO:0030054(cell junction);GO:0045202(synapse);GO:0031410(cytoplasmic vesicle);GO:0050796(regulation of insulin secretion);GO:0030667(secretory granule membrane);GO:0030672(synaptic vesicle membrane);GO:0003674(molecular_function);GO:0006836(neurotransmitter transport);GO:0030658(transport vesicle membrane);GO:0016021(integral component of membrane)","04940(Type I diabetes mellitus)","NA","NA","islet cell autoantigen 1 [Source:HGNC Symbol;Acc:HGNC:5343]",0,{"v":0.032505,"d":"0.03"},"-inf","-inf",1,1,"down","no"]
[152560,0,"chr4","-",183639635,183659225,"ENST00000326397",8,2641,"MSTRG.11928","RWDD4","NA","NA","NA","NA","RWD domain containing 4 [Source:HGNC Symbol;Acc:HGNC:23750]",{"v":0.02478,"d":"0.02"},{"v":1.35985,"d":"1.36"},{"v":0.0182225980806707,"d":"0.02"},{"v":-5.77812752421957,"d":"-5.78"},1,1,"down","no"]
[30401,0,"chr11","-",62835240,62836007,"ENST00000538150",3,487,"MSTRG.2485","WDR74","GO:0005634(nucleus);GO:0005730(nucleolus);GO:0005515(protein binding);GO:0030687(preribosome, large subunit precursor);GO:0003674(molecular_function);GO:0008150(biological_process);GO:0042273(ribosomal large subunit biogenesis)","NA","NA","NA","WD repeat domain 74 [Source:HGNC Symbol;Acc:HGNC:25529]",{"v":0.465697,"d":"0.47"},{"v":0.161169,"d":"0.16"},{"v":2.88949487804727,"d":"2.89"},{"v":1.53081731257752,"d":"1.53"},1,1,"up","no"]
[104147,0,"chr19","+",49850989,49855146,"ENST00000601501",5,564,"MSTRG.8347","PTOV1","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0005886(plasma membrane);GO:0048471(perinuclear region of cytoplasm)","NA","NA","NA","prostate tumor overexpressed 1 [Source:HGNC Symbol;Acc:HGNC:9632]",0,0,1,0,1,1,"no","no"]
[148290,0,"chr4","-",75655066,75658896,"ENST00000510902",3,338,"MSTRG.11660","G3BP2","GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0006810(transport);GO:0051028(mRNA transport);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005622(intracellular);GO:0005515(protein binding);GO:0034063(stress granule assembly);GO:0007265(Ras protein signal transduction);GO:0003729(mRNA binding);GO:0030159(receptor signaling complex scaffold activity);GO:0007253(cytoplasmic sequestering of NF-kappaB);GO:0030529(intracellular ribonucleoprotein complex)","NA","NA","NA","G3BP stress granule assembly factor 2 [Source:HGNC Symbol;Acc:HGNC:30291]",{"v":0.125664,"d":"0.13"},0,"inf","inf",1,1,"up","no"]
[89482,0,"chr17","-",81846947,81859730,"ENST00000574007",5,1053,"MSTRG.7333","P4HB","GO:0003723(RNA binding);GO:0016020(membrane);GO:0016853(isomerase activity);GO:0005783(endoplasmic reticulum);GO:0045454(cell redox homeostasis);GO:0005886(plasma membrane);GO:0055114(oxidation-reduction process);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0042470(melanosome);GO:0051213(dioxygenase activity);GO:0003756(protein disulfide isomerase activity);GO:0005178(integrin binding);GO:0019899(enzyme binding);GO:0046982(protein heterodimerization activity);GO:0009897(external side of plasma membrane);GO:0034663(endoplasmic reticulum chaperone complex);GO:0005925(focal adhesion);GO:0005788(endoplasmic reticulum lumen);GO:0070062(extracellular exosome);GO:0044267(cellular protein metabolic process);GO:0043687(post-translational protein modification);GO:0031012(extracellular matrix);GO:0035722(interleukin-12-mediated signaling pathway);GO:0046598(positive regulation of viral entry into host cell);GO:0034599(cellular response to oxidative stress);GO:0071456(cellular response to hypoxia);GO:0034976(response to endoplasmic reticulum stress);GO:0006457(protein folding);GO:0005793(endoplasmic reticulum-Golgi intermediate compartment);GO:0004656(procollagen-proline 4-dioxygenase activity);GO:0034378(chylomicron assembly);GO:0034379(very-low-density lipoprotein particle assembly);GO:0015037(peptide disulfide oxidoreductase activity);GO:0018401(peptidyl-proline hydroxylation to 4-hydroxy-L-proline);GO:1902175(regulation of oxidative stress-induced intrinsic apoptotic signaling pathway);GO:0016222(procollagen-proline 4-dioxygenase complex);GO:0005623(cell)","04141(Protein processing in endoplasmic reticulum)","NA","NA","prolyl 4-hydroxylase subunit beta [Source:HGNC Symbol;Acc:HGNC:8548]",{"v":1.37099,"d":"1.37"},{"v":0.158899,"d":"0.16"},{"v":8.62805933328718,"d":"8.63"},{"v":3.10903609763245,"d":"3.11"},1,1,"up","no"]
[1788,0,"chr1","+",13731018,13787067,"ENST00000491134",6,1100,"MSTRG.174","PRDM2","GO:0005634(nucleus);GO:0003676(nucleic acid binding);GO:0005794(Golgi apparatus);GO:0046872(metal ion binding);GO:0008168(methyltransferase activity);GO:0016740(transferase activity);GO:0032259(methylation);GO:0006355(regulation of transcription, DNA-templated);GO:0006366(transcription from RNA polymerase II promoter);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0008270(zinc ion binding);GO:0018024(histone-lysine N-methyltransferase activity);GO:0034968(histone lysine methylation);GO:0001228(transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0000977(RNA polymerase II regulatory region sequence-specific DNA binding);GO:0008340(determination of adult lifespan)","00310(Lysine degradation)","NA","NA","PR/SET domain 2 [Source:HGNC Symbol;Acc:HGNC:9347]",{"v":0.41786,"d":"0.42"},0,"inf","inf",1,1,"up","no"]
[117437,0,"chr2","-",191146649,191151596,"ENST00000450994",4,569,"MSTRG.9309","STAT4","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0007165(signal transduction);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0004871(signal transducer activity);GO:0005515(protein binding);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0019221(cytokine-mediated signaling pathway);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0035722(interleukin-12-mediated signaling pathway);GO:0007259(JAK-STAT cascade)","04630(Jak-STAT signaling pathway);04217(Necroptosis);04658(Th1 and Th2 cell differentiation);05200(Pathways in cancer);05321(Inflammatiory bowel disease (IBD));05161(Hepatitis B)","NA","NA","signal transducer and activator of transcription 4 [Source:HGNC Symbol;Acc:HGNC:11365]",0,0,1,0,1,1,"no","no"]
[95587,0,"chr19","-",6735622,6737273,"ENST00000601402",3,816,"MSTRG.7743","GPR108","GO:0016020(membrane);GO:0016021(integral component of membrane)","NA","NA","NA","G protein-coupled receptor 108 [Source:HGNC Symbol;Acc:HGNC:17829]",{"v":0.017158,"d":"0.02"},0,"inf","inf",1,1,"up","no"]
[24474,0,"chr10","-",132808392,132942585,"ENST00000368586",58,8278,"ENSG00000171811","CFAP46","GO:0005737(cytoplasm);GO:0005856(cytoskeleton);GO:0042995(cell projection);GO:0005929(cilium);GO:0030030(cell projection organization);GO:0005930(axoneme);GO:0060294(cilium movement involved in cell motility);GO:0035082(axoneme assembly)","NA","NA","NA","cilia and flagella associated protein 46 [Source:HGNC Symbol;Acc:HGNC:25247]",{"v":0.04035,"d":"0.04"},{"v":0.025001,"d":"0.03"},{"v":1.6139354425823,"d":"1.61"},{"v":0.690582871968183,"d":"0.69"},1,1,"up","no"]
[27659,0,"chr11","-",31456260,31509603,"ENST00000529749",5,475,"ENSG00000148950","IMMP1L","GO:0016020(membrane);GO:0016787(hydrolase activity);GO:0005743(mitochondrial inner membrane);GO:0005739(mitochondrion);GO:0008233(peptidase activity);GO:0006508(proteolysis);GO:0008236(serine-type peptidase activity);GO:0003674(molecular_function);GO:0008150(biological_process);GO:0006627(protein processing involved in protein targeting to mitochondrion);GO:0006465(signal peptide processing);GO:0033108(mitochondrial respiratory chain complex assembly);GO:0042720(mitochondrial inner membrane peptidase complex)","03060(Protein export)","K09647","EC:3.4.21.-","inner mitochondrial membrane peptidase subunit 1 [Source:HGNC Symbol;Acc:HGNC:26317]",{"v":0.013347,"d":"0.01"},{"v":0.07684,"d":"0.08"},{"v":0.173698594482041,"d":"0.17"},{"v":-2.52534201465595,"d":"-2.53"},1,1,"down","no"]
[18057,0,"chr10","+",3133235,3137712,"ENST00000433193",4,453,"MSTRG.1521","PFKP","GO:0006096(glycolytic process);GO:0003872(6-phosphofructokinase activity);GO:0006002(fructose 6-phosphate metabolic process);GO:0061615(glycolytic process through fructose-6-phosphate);GO:0005737(cytoplasm);GO:0005634(nucleus);GO:0016020(membrane);GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0003824(catalytic activity);GO:0008152(metabolic process);GO:0005829(cytosol);GO:0045296(cadherin binding);GO:0070062(extracellular exosome);GO:0031012(extracellular matrix);GO:0032403(protein complex binding);GO:0061621(canonical glycolysis);GO:1990830(cellular response to leukemia inhibitory factor)","00010(Glycolysis / Gluconeogenesis);00030(Pentose phosphate pathway);00051(Fructose and mannose metabolism);00052(Galactose metabolism);03018(RNA degradation);04152(AMPK signaling pathway);04919(Thyroid hormone signaling pathway);05230(Central carbon metabolism in cancer)","NA","NA","phosphofructokinase, platelet [Source:HGNC Symbol;Acc:HGNC:8878]",{"v":0.162384,"d":"0.16"},{"v":0.061148,"d":"0.06"},{"v":2.6555897167528,"d":"2.66"},{"v":1.40903227043165,"d":"1.41"},1,1,"up","no"]
[79863,"j","chr17","-",16381907,16383077,"MSTRG.6461.1",3,886,"MSTRG.6461","AC093484.4","NA","NA","NA","NA","NA",{"v":0.342739,"d":"0.34"},{"v":0.272696,"d":"0.27"},{"v":1.25685378590078,"d":"1.26"},{"v":0.329816825872029,"d":"0.33"},1,1,"up","no"]
[98404,0,"chr19","+",17747762,17762819,"ENST00000598067",6,543,"MSTRG.7982","FCHO1","GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0072583(clathrin-dependent endocytosis);GO:0016020(membrane);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0005905(clathrin-coated pit);GO:0006897(endocytosis);GO:0061024(membrane organization);GO:0048268(clathrin coat assembly);GO:0035612(AP-2 adaptor complex binding)","NA","NA","NA","FCH domain only 1 [Source:HGNC Symbol;Acc:HGNC:29002]",{"v":0.004011,"d":"0.00"},{"v":0.002929,"d":"0.00"},{"v":1.36940935472858,"d":"1.37"},{"v":0.453553772935142,"d":"0.45"},1,1,"up","no"]
[193424,0,"chr9","+",126879348,126885875,"ENST00000373452",1,6528,"MSTRG.14962","ZBTB34","GO:0003676(nucleic acid binding);GO:0005654(nucleoplasm);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding)","NA","NA","NA","zinc finger and BTB domain containing 34 [Source:HGNC Symbol;Acc:HGNC:31446]",{"v":0.074894,"d":"0.07"},{"v":0.080455,"d":"0.08"},{"v":0.930880616493692,"d":"0.93"},{"v":-0.103331937883495,"d":"-0.10"},1,1,"down","no"]
[118986,0,"chr2","+",218217181,218238849,"ENST00000420201",7,732,"MSTRG.9416","ARPC2","GO:0005737(cytoplasm);GO:0003779(actin binding);GO:0015629(actin cytoskeleton);GO:0005856(cytoskeleton);GO:0042995(cell projection);GO:0005515(protein binding);GO:0030054(cell junction);GO:0045202(synapse);GO:0030041(actin filament polymerization);GO:0030833(regulation of actin filament polymerization);GO:0034314(Arp2/3 complex-mediated actin nucleation);GO:0005885(Arp2/3 protein complex);GO:0005925(focal adhesion);GO:0038096(Fc-gamma receptor signaling pathway involved in phagocytosis);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0061024(membrane organization);GO:0043005(neuron projection);GO:0005200(structural constituent of cytoskeleton);GO:0006928(movement of cell or subcellular component);GO:0048013(ephrin receptor signaling pathway);GO:0051015(actin filament binding);GO:0010592(positive regulation of lamellipodium assembly);GO:0030838(positive regulation of actin filament polymerization);GO:1900026(positive regulation of substrate adhesion-dependent cell spreading);GO:0005768(endosome);GO:0005886(plasma membrane);GO:0031252(cell leading edge);GO:0036195(muscle cell projection membrane)","04144(Endocytosis);04810(Regulation of actin cytoskeleton);04666(Fc gamma R-mediated phagocytosis);05130(Pathogenic Escherichia coli infection);05132(Salmonella infection);05131(Shigellosis);05100(Bacterial invasion of epithelial cells)","NA","NA","actin related protein 2/3 complex subunit 2 [Source:HGNC Symbol;Acc:HGNC:705]",{"v":3.046408,"d":"3.05"},0,"inf","inf",1,1,"up","no"]
[8726,0,"chr1","-",108934658,108950448,"ENST00000302500",8,1316,"ENSG00000121940","CLCC1","GO:0006810(transport);GO:0005634(nucleus);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0043231(intracellular membrane-bounded organelle);GO:0005783(endoplasmic reticulum);GO:0005794(Golgi apparatus);GO:0006811(ion transport);GO:0005254(chloride channel activity);GO:0006821(chloride transport);GO:0034707(chloride channel complex);GO:1902476(chloride transmembrane transport)","NA","NA","NA","chloride channel CLIC like 1 [Source:HGNC Symbol;Acc:HGNC:29675]",{"v":2.727464,"d":"2.73"},0,"inf","inf",1,1,"up","no"]
[132476,0,"chr22","-",50245507,50251032,"ENST00000349505",19,1950,"MSTRG.10602","HDAC10","GO:0016787(hydrolase activity);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0004407(histone deacetylase activity);GO:0032041(NAD-dependent histone deacetylase activity (H3-K14 specific));GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0016569(covalent chromatin modification);GO:0070932(histone H3 deacetylation);GO:0006476(protein deacetylation);GO:0005654(nucleoplasm);GO:0006325(chromatin organization);GO:0005515(protein binding);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0000118(histone deacetylase complex);GO:0019899(enzyme binding);GO:0045892(negative regulation of transcription, DNA-templated);GO:0033558(protein deacetylase activity);GO:0042826(histone deacetylase binding);GO:0016575(histone deacetylation);GO:0014003(oligodendrocyte development)","05203(Viral carcinogenesis);05034(Alcoholism);05165(Human papillomavirus infection)","K18671","EC:3.5.1.98","histone deacetylase 10 [Source:HGNC Symbol;Acc:HGNC:18128]",{"v":0.183503,"d":"0.18"},0,"inf","inf",1,1,"up","no"]
[70665,0,"chr16","+",21953371,21983325,"ENST00000561553",13,1415,"MSTRG.5738","UQCRC2","GO:0016020(membrane);GO:0005654(nucleoplasm);GO:0055114(oxidation-reduction process);GO:0005739(mitochondrion);GO:0005743(mitochondrial inner membrane);GO:0046872(metal ion binding);GO:0003824(catalytic activity);GO:0005515(protein binding);GO:0006508(proteolysis);GO:0004222(metalloendopeptidase activity);GO:0070469(respiratory chain);GO:0070062(extracellular exosome);GO:0005751(mitochondrial respiratory chain complex IV);GO:0008270(zinc ion binding);GO:0006122(mitochondrial electron transport, ubiquinol to cytochrome c);GO:0009060(aerobic respiration);GO:0005750(mitochondrial respiratory chain complex III);GO:0006119(oxidative phosphorylation);GO:0032403(protein complex binding);GO:0006627(protein processing involved in protein targeting to mitochondrion);GO:0043209(myelin sheath)","00190(Oxidative phosphorylation);04260(Cardiac muscle contraction);05010(Alzheimer's disease);05012(Parkinson's disease);05016(Huntington's disease);04932(Non-alcoholic fatty liver disease (NAFLD))","NA","NA","ubiquinol-cytochrome c reductase core protein II [Source:HGNC Symbol;Acc:HGNC:12586]",0,{"v":0.316578,"d":"0.32"},"-inf","-inf",1,1,"down","no"]
[179057,0,"chr7","+",135926455,135932881,"ENST00000419211",2,804,"MSTRG.13992","AC015987.1","NA","NA","NA","NA","NA",{"v":0.00341,"d":"0.00"},0,"inf","inf",1,1,"up","no"]
[80078,0,"chr17","-",17505563,17519080,"ENST00000490392",5,673,"ENSG00000133027","PEMT","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0008168(methyltransferase activity);GO:0016740(transferase activity);GO:0032259(methylation);GO:0006629(lipid metabolic process);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005739(mitochondrion);GO:0008654(phospholipid biosynthetic process);GO:0006644(phospholipid metabolic process);GO:0031966(mitochondrial membrane);GO:0008170(N-methyltransferase activity);GO:0000773(phosphatidyl-N-methylethanolamine N-methyltransferase activity);GO:0004608(phosphatidylethanolamine N-methyltransferase activity);GO:0080101(phosphatidyl-N-dimethylethanolamine N-methyltransferase activity);GO:0006656(phosphatidylcholine biosynthetic process);GO:0008283(cell proliferation);GO:1903955(positive regulation of protein targeting to mitochondrion);GO:0008429(phosphatidylethanolamine binding);GO:0008757(S-adenosylmethionine-dependent methyltransferase activity);GO:0006650(glycerophospholipid metabolic process);GO:0006686(sphingomyelin biosynthetic process);GO:0007584(response to nutrient);GO:0008285(negative regulation of cell proliferation);GO:0033273(response to vitamin);GO:0042493(response to drug);GO:0043200(response to amino acid);GO:0045471(response to ethanol);GO:0046498(S-adenosylhomocysteine metabolic process);GO:0046500(S-adenosylmethionine metabolic process);GO:0050747(positive regulation of lipoprotein metabolic process);GO:0031526(brush border membrane);GO:0042383(sarcolemma)","00564(Glycerophospholipid metabolism)","NA","NA","phosphatidylethanolamine N-methyltransferase [Source:HGNC Symbol;Acc:HGNC:8830]",{"v":3.31E-3,"d":"0.00"},0,"inf","inf",1,1,"up","no"]
[107766,0,"chr2","-",24115371,24123477,"ENST00000313213",5,974,"MSTRG.8543","PFN4","GO:0005737(cytoplasm);GO:0005856(cytoskeleton);GO:0008289(lipid binding);GO:0005938(cell cortex);GO:0015629(actin cytoskeleton);GO:0003785(actin monomer binding);GO:0042989(sequestering of actin monomers)","04015(Rap1 signaling pathway);04810(Regulation of actin cytoskeleton);05132(Salmonella infection);05131(Shigellosis)","K05759","NA","profilin family member 4 [Source:HGNC Symbol;Acc:HGNC:31103]",0,{"v":0.011242,"d":"0.01"},"-inf","-inf",1,1,"down","no"]
[140375,0,"chr3","+",129440139,129520345,"ENST00000296266",31,4151,"MSTRG.11190","IFT122","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0005856(cytoskeleton);GO:0042995(cell projection);GO:0005515(protein binding);GO:0007275(multicellular organism development);GO:0035735(intraciliary transport involved in cilium assembly);GO:0060271(cilium assembly);GO:0005929(cilium);GO:0097542(ciliary tip);GO:0030030(cell projection organization);GO:0001843(neural tube closure);GO:0032391(photoreceptor connecting cilium);GO:0060173(limb development);GO:0030991(intraciliary transport particle A);GO:0045879(negative regulation of smoothened signaling pathway);GO:0035050(embryonic heart tube development);GO:0035721(intraciliary retrograde transport);GO:0061512(protein localization to cilium);GO:0048593(camera-type eye morphogenesis);GO:0010172(embryonic body morphogenesis);GO:0007227(signal transduction downstream of smoothened);GO:0009953(dorsal/ventral pattern formation);GO:0021914(negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning);GO:0035115(embryonic forelimb morphogenesis);GO:0035720(intraciliary anterograde transport);GO:0042733(embryonic digit morphogenesis);GO:0050680(negative regulation of epithelial cell proliferation);GO:0060830(ciliary receptor clustering involved in smoothened signaling pathway);GO:0060831(smoothened signaling pathway involved in dorsal/ventral neural tube patterning);GO:0060971(embryonic heart tube left/right pattern formation);GO:0072594(establishment of protein localization to organelle);GO:1905515(non-motile cilium assembly);GO:0036064(ciliary basal body);GO:0097546(ciliary base)","NA","NA","NA","intraflagellar transport 122 [Source:HGNC Symbol;Acc:HGNC:13556]",{"v":0.483737,"d":"0.48"},0,"inf","inf",1,1,"up","no"]
[119040,0,"chr2","-",218280077,218292535,"ENST00000453281",4,534,"MSTRG.9420","TMBIM1","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0043231(intracellular membrane-bounded organelle);GO:0005794(Golgi apparatus);GO:0005765(lysosomal membrane);GO:0005764(lysosome);GO:0005886(plasma membrane);GO:0005768(endosome);GO:0070062(extracellular exosome);GO:0010008(endosome membrane);GO:0043312(neutrophil degranulation);GO:0035579(specific granule membrane);GO:0043086(negative regulation of catalytic activity);GO:2000504(positive regulation of blood vessel remodeling);GO:1902042(negative regulation of extrinsic apoptotic signaling pathway via death domain receptors);GO:0090005(negative regulation of establishment of protein localization to plasma membrane);GO:0005123(death receptor binding);GO:1902045(negative regulation of Fas signaling pathway)","NA","NA","NA","transmembrane BAX inhibitor motif containing 1 [Source:HGNC Symbol;Acc:HGNC:23410]",0,0,1,0,1,1,"no","no"]
[5510,0,"chr1","-",45515654,45521867,"ENST00000483583",3,530,"MSTRG.520","PRDX1","GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0045454(cell redox homeostasis);GO:0005515(protein binding);GO:0042470(melanosome);GO:0005615(extracellular space);GO:0004601(peroxidase activity);GO:0051920(peroxiredoxin activity);GO:0016209(antioxidant activity);GO:0005829(cytosol);GO:0045296(cadherin binding);GO:0070062(extracellular exosome);GO:0001895(retina homeostasis);GO:0031012(extracellular matrix);GO:0001501(skeletal system development);GO:0030101(natural killer cell activation);GO:0008283(cell proliferation);GO:0034599(cellular response to oxidative stress);GO:0042744(hydrogen peroxide catabolic process);GO:0008379(thioredoxin peroxidase activity);GO:0098869(cellular oxidant detoxification);GO:0005623(cell);GO:0042802(identical protein binding);GO:0000302(response to reactive oxygen species);GO:0006979(response to oxidative stress);GO:0019430(removal of superoxide radicals);GO:0032872(regulation of stress-activated MAPK cascade);GO:0034101(erythrocyte homeostasis);GO:0042267(natural killer cell mediated cytotoxicity);GO:0042345(regulation of NF-kappaB import into nucleus);GO:0005739(mitochondrion);GO:0043209(myelin sheath)","04146(Peroxisome)","NA","NA","peroxiredoxin 1 [Source:HGNC Symbol;Acc:HGNC:9352]",0,0,1,0,1,1,"no","no"]
[147600,0,"chr4","-",56393365,56400916,"ENST00000425339",3,4043,"ENSG00000128059","PPAT","GO:0046872(metal ion binding);GO:0016740(transferase activity);GO:0009116(nucleoside metabolic process);GO:0016757(transferase activity, transferring glycosyl groups);GO:0003824(catalytic activity);GO:0008152(metabolic process);GO:0051536(iron-sulfur cluster binding);GO:0051539(4 iron, 4 sulfur cluster binding);GO:0006164(purine nucleotide biosynthetic process);GO:0006541(glutamine metabolic process);GO:0006189('de novo' IMP biosynthetic process);GO:0005829(cytosol);GO:0004044(amidophosphoribosyltransferase activity);GO:0000082(G1/S transition of mitotic cell cycle);GO:0001822(kidney development);GO:0006543(glutamine catabolic process);GO:0007595(lactation);GO:0009113(purine nucleobase biosynthetic process);GO:0009168(purine ribonucleoside monophosphate biosynthetic process);GO:0019693(ribose phosphate metabolic process);GO:0031100(animal organ regeneration);GO:0032869(cellular response to insulin stimulus);GO:0035690(cellular response to drug);GO:0042493(response to drug);GO:0051289(protein homotetramerization);GO:0060135(maternal process involved in female pregnancy)","00230(Purine metabolism);00250(Alanine, aspartate and glutamate metabolism)","NA","NA","phosphoribosyl pyrophosphate amidotransferase [Source:HGNC Symbol;Acc:HGNC:9238]",{"v":7.7e-05,"d":"0.00"},0,"inf","inf",1,1,"up","no"]
[61161,0,"chr15","+",40406074,40411690,"ENST00000558610",6,819,"ENSG00000128928","IVD","GO:0050660(flavin adenine dinucleotide binding);GO:0055114(oxidation-reduction process);GO:0016627(oxidoreductase activity, acting on the CH-CH group of donors);GO:0008152(metabolic process);GO:0003995(acyl-CoA dehydrogenase activity);GO:0005654(nucleoplasm);GO:0016491(oxidoreductase activity);GO:0005739(mitochondrion);GO:0008470(isovaleryl-CoA dehydrogenase activity);GO:0006552(leucine catabolic process);GO:0005759(mitochondrial matrix);GO:0031966(mitochondrial membrane);GO:0009083(branched-chain amino acid catabolic process)","00280(Valine, leucine and isoleucine degradation)","NA","NA","isovaleryl-CoA dehydrogenase [Source:HGNC Symbol;Acc:HGNC:6186]",{"v":0.097812,"d":"0.10"},{"v":0.090602,"d":"0.09"},{"v":1.07957881724465,"d":"1.08"},{"v":0.110468574622194,"d":"0.11"},1,1,"up","no"]
[195228,0,"chr9","+",137738607,137754221,"ENST00000495657",5,649,"MSTRG.15148","EHMT1","GO:0005634(nucleus);GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0005654(nucleoplasm);GO:0008168(methyltransferase activity);GO:0016740(transferase activity);GO:0032259(methylation);GO:0016569(covalent chromatin modification);GO:0005694(chromosome);GO:0005515(protein binding);GO:0016604(nuclear body);GO:0018024(histone-lysine N-methyltransferase activity);GO:0018026(peptidyl-lysine monomethylation);GO:0018027(peptidyl-lysine dimethylation);GO:0034968(histone lysine methylation);GO:0016279(protein-lysine N-methyltransferase activity);GO:0006325(chromatin organization);GO:0045892(negative regulation of transcription, DNA-templated);GO:1901796(regulation of signal transduction by p53 class mediator);GO:0009790(embryo development);GO:0002039(p53 binding);GO:0046974(histone methyltransferase activity (H3-K9 specific));GO:0046976(histone methyltransferase activity (H3-K27 specific));GO:0070734(histone H3-K27 methylation);GO:0016571(histone methylation);GO:0006306(DNA methylation);GO:0051567(histone H3-K9 methylation);GO:0070742(C2H2 zinc finger domain binding);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0060992(response to fungicide);GO:0016020(membrane);GO:0016021(integral component of membrane)","00310(Lysine degradation);04211(Longevity regulating pathway - mammal)","NA","NA","euchromatic histone lysine methyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:24650]",{"v":0.033883,"d":"0.03"},{"v":0.025776,"d":"0.03"},{"v":1.314517380509,"d":"1.31"},{"v":0.394533217352211,"d":"0.39"},1,1,"up","no"]
[49229,0,"chr13","+",26396217,26405178,"ENST00000477277",6,1770,"ENSG00000132964","CDK8","GO:0004672(protein kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0005634(nucleus);GO:0000166(nucleotide binding);GO:0004674(protein serine/threonine kinase activity);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0005515(protein binding);GO:0005654(nucleoplasm);GO:0043234(protein complex);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0006367(transcription initiation from RNA polymerase II promoter);GO:0007346(regulation of mitotic cell cycle);GO:0005730(nucleolus);GO:0016592(mediator complex);GO:0004693(cyclin-dependent protein serine/threonine kinase activity);GO:0008353(RNA polymerase II carboxy-terminal domain kinase activity)","NA","NA","NA","cyclin dependent kinase 8 [Source:HGNC Symbol;Acc:HGNC:1779]",{"v":0.822318,"d":"0.82"},{"v":0.185722,"d":"0.19"},{"v":4.42768223473794,"d":"4.43"},{"v":2.1465516867044,"d":"2.15"},1,1,"up","no"]
[56491,0,"chr14","+",72926499,72940526,"ENST00000514191",4,553,"ENSG00000119599","DCAF4","GO:0016567(protein ubiquitination);GO:0003723(RNA binding);GO:0005654(nucleoplasm);GO:0043687(post-translational protein modification);GO:0005682(U5 snRNP);GO:0008380(RNA splicing);GO:0071011(precatalytic spliceosome);GO:0071013(catalytic step 2 spliceosome);GO:0080008(Cul4-RING E3 ubiquitin ligase complex)","NA","NA","NA","DDB1 and CUL4 associated factor 4 [Source:HGNC Symbol;Acc:HGNC:20229]",{"v":0.293551,"d":"0.29"},{"v":0.154042,"d":"0.15"},{"v":1.90565560042066,"d":"1.91"},{"v":0.930287411766051,"d":"0.93"},1,1,"up","no"]
[60289,0,"chr15","-",28190201,28203936,"ENST00000567869",10,3523,"ENSG00000128731","HERC2","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0016740(transferase activity);GO:0016567(protein ubiquitination);GO:0004842(ubiquitin-protein transferase activity);GO:0043547(positive regulation of GTPase activity);GO:0005856(cytoskeleton);GO:0006281(DNA repair);GO:0006974(cellular response to DNA damage stimulus);GO:0006886(intracellular protein transport);GO:0005085(guanyl-nucleotide exchange factor activity);GO:0061630(ubiquitin protein ligase activity);GO:0043161(proteasome-mediated ubiquitin-dependent protein catabolic process);GO:0005515(protein binding);GO:0005654(nucleoplasm);GO:0005814(centriole);GO:0031625(ubiquitin protein ligase binding);GO:0006303(double-strand break repair via nonhomologous end joining);GO:0032183(SUMO binding);GO:0007283(spermatogenesis);GO:0005743(mitochondrial inner membrane)","04120(Ubiquitin mediated proteolysis)","NA","NA","HECT and RLD domain containing E3 ubiquitin protein ligase 2 [Source:HGNC Symbol;Acc:HGNC:4868]",{"v":0.057706,"d":"0.06"},0,"inf","inf",1,1,"up","no"]
[105496,0,"chr19","-",54360982,54370491,"ENST00000438193",3,494,"ENSG00000167613","LAIR1","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0002376(immune system process);GO:0002250(adaptive immune response);GO:0050776(regulation of immune response);GO:0070062(extracellular exosome);GO:0043312(neutrophil degranulation);GO:0035579(specific granule membrane);GO:0070821(tertiary granule membrane)","NA","NA","NA","leukocyte associated immunoglobulin like receptor 1 [Source:HGNC Symbol;Acc:HGNC:6477]",0,{"v":0.901544,"d":"0.90"},"-inf","-inf",1,1,"down","no"]
[133234,0,"chr3","-",9945542,9952394,"ENST00000412055",4,3761,"ENSG00000163704","PRRT3","GO:0016020(membrane);GO:0016021(integral component of membrane)","NA","NA","NA","proline rich transmembrane protein 3 [Source:HGNC Symbol;Acc:HGNC:26591]",0,{"v":0.384855,"d":"0.38"},"-inf","-inf",1,1,"down","no"]
[82014,0,"chr17","-",32509954,32523424,"ENST00000578408",2,927,"MSTRG.6681","AC079336.2","NA","NA","NA","NA","NA",0,0,1,0,1,1,"no","no"]
[121193,0,"chr2","-",241501357,241508583,"ENST00000495372",3,561,"MSTRG.9527","STK25","GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0000165(MAPK cascade);GO:0016310(phosphorylation);GO:0005794(Golgi apparatus);GO:0042803(protein homodimerization activity);GO:0005515(protein binding);GO:0007163(establishment or maintenance of cell polarity);GO:0050772(positive regulation of axonogenesis);GO:0051645(Golgi localization);GO:0000139(Golgi membrane);GO:0000185(activation of MAPKKK activity);GO:0070062(extracellular exosome);GO:0048812(neuron projection morphogenesis);GO:0006979(response to oxidative stress);GO:0007165(signal transduction);GO:0042981(regulation of apoptotic process);GO:0046777(protein autophosphorylation);GO:0008349(MAP kinase kinase kinase kinase activity);GO:0007346(regulation of mitotic cell cycle);GO:0032874(positive regulation of stress-activated MAPK cascade);GO:0036481(intrinsic apoptotic signaling pathway in response to hydrogen peroxide);GO:0042542(response to hydrogen peroxide);GO:0051683(establishment of Golgi localization);GO:0090168(Golgi reassembly)","NA","NA","NA","serine/threonine kinase 25 [Source:HGNC Symbol;Acc:HGNC:11404]",0,{"v":0.309411,"d":"0.31"},"-inf","-inf",1,1,"down","no"]
[56911,0,"chr14","-",75016787,75051457,"ENST00000556257",7,4229,"MSTRG.4546","MLH3","GO:0005634(nucleus);GO:0005524(ATP binding);GO:0006281(DNA repair);GO:0006974(cellular response to DNA damage stimulus);GO:0030983(mismatched DNA binding);GO:0006298(mismatch repair);GO:0005515(protein binding);GO:0007131(reciprocal meiotic recombination);GO:0016887(ATPase activity);GO:0000795(synaptonemal complex);GO:0032300(mismatch repair complex);GO:0003697(single-stranded DNA binding);GO:0003696(satellite DNA binding);GO:0005712(chiasma);GO:0003682(chromatin binding);GO:0019237(centromeric DNA binding);GO:0007130(synaptonemal complex assembly);GO:0007140(male meiotic nuclear division);GO:0007144(female meiosis I);GO:0008104(protein localization);GO:0000793(condensed chromosome);GO:0000794(condensed nuclear chromosome);GO:0001673(male germ cell nucleus)","03430(Mismatch repair)","NA","NA","mutL homolog 3 [Source:HGNC Symbol;Acc:HGNC:7128]",0,{"v":0.114687,"d":"0.11"},"-inf","-inf",1,1,"down","no"]
[86700,0,"chr17","+",63688529,63689692,"ENST00000577784",3,565,"MSTRG.7130","MAP3K3","GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0005515(protein binding);GO:0004709(MAP kinase kinase kinase activity);GO:0000186(activation of MAPKK activity);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0000165(MAPK cascade);GO:0043123(positive regulation of I-kappaB kinase/NF-kappaB signaling);GO:0042981(regulation of apoptotic process);GO:0007346(regulation of mitotic cell cycle);GO:0035556(intracellular signal transduction);GO:0031098(stress-activated protein kinase signaling cascade);GO:0032147(activation of protein kinase activity);GO:0046777(protein autophosphorylation);GO:0005622(intracellular);GO:0001568(blood vessel development);GO:1900745(positive regulation of p38MAPK cascade)","04010(MAPK signaling pathway);04912(GnRH signaling pathway);04722(Neurotrophin signaling pathway);05166(HTLV-I infection)","NA","NA","mitogen-activated protein kinase kinase kinase 3 [Source:HGNC Symbol;Acc:HGNC:6855]",{"v":0.42296,"d":"0.42"},{"v":0.216429,"d":"0.22"},{"v":1.95426675722754,"d":"1.95"},{"v":0.966627408484473,"d":"0.97"},1,1,"up","no"]
[46524,0,"chr12","+",110036215,110038006,"ENST00000553246",2,762,"MSTRG.3704","ANKRD13A","GO:0016020(membrane);GO:0005886(plasma membrane);GO:0005737(cytoplasm);GO:0005768(endosome);GO:0005770(late endosome)","NA","NA","NA","ankyrin repeat domain 13A [Source:HGNC Symbol;Acc:HGNC:21268]",{"v":0.003541,"d":"0.00"},{"v":0.102046,"d":"0.10"},{"v":0.0347000372381083,"d":"0.03"},{"v":-4.84891897875201,"d":"-4.85"},1,1,"down","no"]
[146266,0,"chr4","-",17587467,17614571,"ENST00000511010",3,750,"MSTRG.11542","AC006160.1","NA","NA","NA","NA","NA",{"v":0.044007,"d":"0.04"},0,"inf","inf",1,1,"up","no"]
[38367,0,"chr12","-",7729442,7747505,"ENST00000540085",5,860,"ENSG00000198178","CLEC4C","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0030246(carbohydrate binding);GO:0002376(immune system process);GO:0045087(innate immune response);GO:0002250(adaptive immune response);GO:0005886(plasma membrane);GO:0002223(stimulatory C-type lectin receptor signaling pathway);GO:0043312(neutrophil degranulation);GO:0070821(tertiary granule membrane);GO:0030667(secretory granule membrane);GO:0101003(ficolin-1-rich granule membrane)","NA","NA","NA","C-type lectin domain family 4 member C [Source:HGNC Symbol;Acc:HGNC:13258]",0,{"v":0.163168,"d":"0.16"},"-inf","-inf",1,1,"down","no"]
[75671,0,"chr16","-",74712955,74774825,"ENST00000219368",7,2424,"ENSG00000103089","FA2H","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0046872(metal ion binding);GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0006629(lipid metabolic process);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0006631(fatty acid metabolic process);GO:0006633(fatty acid biosynthetic process);GO:0005506(iron ion binding);GO:0008610(lipid biosynthetic process);GO:0020037(heme binding);GO:0043231(intracellular membrane-bounded organelle);GO:0031090(organelle membrane);GO:0030148(sphingolipid biosynthetic process);GO:0080132(fatty acid alpha-hydroxylase activity);GO:0001949(sebaceous gland cell differentiation);GO:0030258(lipid modification);GO:0032286(central nervous system myelin maintenance);GO:0032287(peripheral nervous system myelin maintenance);GO:0042127(regulation of cell proliferation);GO:0042634(regulation of hair cycle)","NA","NA","NA","fatty acid 2-hydroxylase [Source:HGNC Symbol;Acc:HGNC:21197]",{"v":0.076693,"d":"0.08"},{"v":0.11701,"d":"0.12"},{"v":0.655439706008033,"d":"0.66"},{"v":-0.609465022058949,"d":"-0.61"},1,1,"down","no"]
[81896,0,"chr17","+",32021142,32053504,"ENST00000341671",12,3025,"ENSG00000185158","LRRC37B","GO:0016020(membrane);GO:0016021(integral component of membrane)","NA","NA","NA","leucine rich repeat containing 37B [Source:HGNC Symbol;Acc:HGNC:29070]",0,0,1,0,1,1,"no","no"]
[155563,0,"chr5","+",70025563,70026515,"ENST00000507177",3,338,"ENSG00000205572","SERF1B","GO:0003674(molecular_function);GO:0005575(cellular_component);GO:0007399(nervous system development);GO:0016020(membrane);GO:0016021(integral component of membrane)","NA","NA","NA","small EDRK-rich factor 1B [Source:HGNC Symbol;Acc:HGNC:10756]",0,0,1,0,1,1,"no","no"]
[183189,0,"chr8","+",38974164,38988662,"ENST00000302495",9,2095,"ENSG00000169495","HTRA4","GO:0016787(hydrolase activity);GO:0005576(extracellular region);GO:0008233(peptidase activity);GO:0006508(proteolysis);GO:0004252(serine-type endopeptidase activity);GO:0005520(insulin-like growth factor binding);GO:0001558(regulation of cell growth);GO:0008236(serine-type peptidase activity);GO:0004175(endopeptidase activity);GO:0030512(negative regulation of transforming growth factor beta receptor signaling pathway)","NA","NA","NA","HtrA serine peptidase 4 [Source:HGNC Symbol;Acc:HGNC:26909]",{"v":0.012876,"d":"0.01"},{"v":0.021777,"d":"0.02"},{"v":0.591266014602562,"d":"0.59"},{"v":-0.758120740114308,"d":"-0.76"},1,1,"down","no"]
[39032,0,"chr12","+",12357121,12469694,"ENST00000314565",4,4840,"ENSG00000165714","BORCS5","GO:0016020(membrane);GO:0005765(lysosomal membrane);GO:0005515(protein binding);GO:0005764(lysosome);GO:0031224(intrinsic component of membrane);GO:0032418(lysosome localization);GO:0099078(BORC complex);GO:0005873(plus-end kinesin complex);GO:0072384(organelle transport along microtubule);GO:0098574(cytoplasmic side of lysosomal membrane)","NA","NA","NA","BLOC-1 related complex subunit 5 [Source:HGNC Symbol;Acc:HGNC:17950]",{"v":0.829619,"d":"0.83"},{"v":0.127937,"d":"0.13"},{"v":6.4845900716759,"d":"6.48"},{"v":2.69701537628841,"d":"2.70"},1,1,"up","no"]
[101740,0,"chr19","-",40908480,40910685,"ENST00000600605",4,641,"ENSG00000198251","CYP2A7P2","NA","NA","NA","NA","cytochrome P450 family 2 subfamily A member 7 pseudogene 2 [Source:HGNC Symbol;Acc:HGNC:2613]",{"v":0.039413,"d":"0.04"},{"v":0.238143,"d":"0.24"},{"v":0.165501400419076,"d":"0.17"},{"v":-2.59508467018654,"d":"-2.60"},1,1,"down","no"]
[112582,0,"chr2","+",97422165,97423309,"ENST00000618807",2,788,"ENSG00000278766","AC092683.2","NA","NA","NA","NA","NA",0,0,1,0,1,1,"no","no"]
[11744,0,"chr1","+",155319655,155320609,"ENST00000489324",2,475,"MSTRG.1045","FDPS","GO:0003723(RNA binding);GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0016740(transferase activity);GO:0006629(lipid metabolic process);GO:0006694(steroid biosynthetic process);GO:0008202(steroid metabolic process);GO:0008299(isoprenoid biosynthetic process);GO:0016126(sterol biosynthetic process);GO:0008203(cholesterol metabolic process);GO:0006695(cholesterol biosynthetic process);GO:0016032(viral process);GO:0045540(regulation of cholesterol biosynthetic process);GO:0004161(dimethylallyltranstransferase activity);GO:0004337(geranyltranstransferase activity);GO:0033384(geranyl diphosphate biosynthetic process);GO:0045337(farnesyl diphosphate biosynthetic process);GO:0005739(mitochondrion);GO:0016020(membrane);GO:0016021(integral component of membrane)","00900(Terpenoid backbone biosynthesis);05166(HTLV-I infection);05164(Influenza A)","NA","NA","farnesyl diphosphate synthase [Source:HGNC Symbol;Acc:HGNC:3631]",{"v":0.041499,"d":"0.04"},0,"inf","inf",1,1,"up","no"]
[20152,0,"chr10","+",47322490,47326270,"ENST00000581492",2,1955,"ENSG00000263761","GDF2","GO:0010596(negative regulation of endothelial cell migration);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0030509(BMP signaling pathway);GO:0005623(cell);GO:0008083(growth factor activity);GO:0005576(extracellular region);GO:0005125(cytokine activity);GO:0005615(extracellular space);GO:0070062(extracellular exosome);GO:0005515(protein binding);GO:0060395(SMAD protein signal transduction);GO:0032757(positive regulation of interleukin-8 production);GO:0045893(positive regulation of transcription, DNA-templated);GO:0071773(cellular response to BMP stimulus);GO:0005160(transforming growth factor beta receptor binding);GO:0042981(regulation of apoptotic process);GO:0043408(regulation of MAPK cascade);GO:0048468(cell development);GO:0001525(angiogenesis);GO:0060389(pathway-restricted SMAD protein phosphorylation);GO:0030308(negative regulation of cell growth);GO:0010862(positive regulation of pathway-restricted SMAD protein phosphorylation);GO:0032924(activin receptor signaling pathway);GO:0045766(positive regulation of angiogenesis);GO:2000279(negative regulation of DNA biosynthetic process);GO:0001503(ossification);GO:0001569(branching involved in blood vessel morphogenesis);GO:0001570(vasculogenesis);GO:0001649(osteoblast differentiation);GO:0001937(negative regulation of endothelial cell proliferation);GO:0001938(positive regulation of endothelial cell proliferation);GO:0006879(cellular iron ion homeostasis);GO:0008156(negative regulation of DNA replication);GO:0010628(positive regulation of gene expression);GO:0016525(negative regulation of angiogenesis);GO:0030513(positive regulation of BMP signaling pathway);GO:0043537(negative regulation of blood vessel endothelial cell migration);GO:0045603(positive regulation of endothelial cell differentiation);GO:0045669(positive regulation of osteoblast differentiation);GO:0048514(blood vessel morphogenesis);GO:0051216(cartilage development);GO:0061036(positive regulation of cartilage development)","NA","NA","NA","growth differentiation factor 2 [Source:HGNC Symbol;Acc:HGNC:4217]",{"v":0.048115,"d":"0.05"},0,"inf","inf",1,1,"up","no"]
[64500,0,"chr15","+",73994717,74036394,"ENST00000354026",7,2885,"ENSG00000140464","PML","GO:0008285(negative regulation of cell proliferation);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0005622(intracellular);GO:0005829(cytosol);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005515(protein binding);GO:0048511(rhythmic process);GO:0006915(apoptotic process);GO:0005654(nucleoplasm);GO:0002376(immune system process);GO:0045087(innate immune response);GO:0005730(nucleolus);GO:0051607(defense response to virus);GO:0005768(endosome);GO:0000784(nuclear chromosome, telomeric region);GO:0001666(response to hypoxia);GO:0016032(viral process);GO:0031625(ubiquitin protein ligase binding);GO:0031901(early endosome membrane);GO:0042803(protein homodimerization activity);GO:0030308(negative regulation of cell growth);GO:0045892(negative regulation of transcription, DNA-templated);GO:1901796(regulation of signal transduction by p53 class mediator);GO:0043161(proteasome-mediated ubiquitin-dependent protein catabolic process);GO:0032922(circadian regulation of gene expression);GO:0016605(PML body);GO:0016525(negative regulation of angiogenesis);GO:0060333(interferon-gamma-mediated signaling pathway);GO:0042406(extrinsic component of endoplasmic reticulum membrane);GO:0006461(protein complex assembly);GO:0001932(regulation of protein phosphorylation);GO:0042752(regulation of circadian rhythm);GO:0090398(cellular senescence);GO:0042771(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator);GO:0043153(entrainment of circadian clock by photoperiod);GO:2001238(positive regulation of extrinsic apoptotic signaling pathway);GO:2000059(negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process);GO:1902187(negative regulation of viral release from host cell);GO:0032206(positive regulation of telomere maintenance);GO:0032183(SUMO binding);GO:0034097(response to cytokine);GO:0032469(endoplasmic reticulum calcium ion homeostasis);GO:0006977(DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest);GO:0010522(regulation of calcium ion transport into cytosol);GO:0030578(PML body organization);GO:0051457(maintenance of protein location in nucleus);GO:2000779(regulation of double-strand break repair);GO:0046332(SMAD binding);GO:0006919(activation of cysteine-type endopeptidase activity involved in apoptotic process);GO:0007050(cell cycle arrest);GO:0007179(transforming growth factor beta receptor signaling pathway);GO:0007182(common-partner SMAD protein phosphorylation);GO:0007184(SMAD protein import into nucleus);GO:0007569(cell aging);GO:0008630(intrinsic apoptotic signaling pathway in response to DNA damage);GO:0008631(intrinsic apoptotic signaling pathway in response to oxidative stress);GO:0009411(response to UV);GO:0010332(response to gamma radiation);GO:0010761(fibroblast migration);GO:0030099(myeloid cell differentiation);GO:0030155(regulation of cell adhesion);GO:0045165(cell fate commitment);GO:0045343(regulation of MHC class I biosynthetic process);GO:0045345(positive regulation of MHC class I biosynthetic process);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0048146(positive regulation of fibroblast proliferation);GO:0048384(retinoic acid receptor signaling pathway);GO:0050711(negative regulation of interleukin-1 secretion);GO:0050713(negative regulation of interleukin-1 beta secretion);GO:0060444(branching involved in mammary gland duct morphogenesis);GO:0070059(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress);GO:0071353(cellular response to interleukin-4);GO:0072332(intrinsic apoptotic signaling pathway by p53 class mediator);GO:0097191(extrinsic apoptotic signaling pathway);GO:1990830(cellular response to leukemia inhibitory factor);GO:2001235(positive regulation of apoptotic signaling pathway);GO:0000792(heterochromatin);GO:0016363(nuclear matrix)","04120(Ubiquitin mediated proteolysis);04144(Endocytosis);05200(Pathways in cancer);05202(Transcriptional misregulation in cancers);05221(Acute myeloid leukemia);05164(Influenza A);05168(Herpes simplex infection)","K10054","NA","promyelocytic leukemia [Source:HGNC Symbol;Acc:HGNC:9113]",0,{"v":4.064497,"d":"4.06"},"-inf","-inf",1,1,"down","no"]
[144351,0,"chr3","+",195658065,195664109,"ENST00000452844",5,583,"ENSG00000242086","LINC00969","NA","NA","NA","NA","long intergenic non-protein coding RNA 969 [Source:HGNC Symbol;Acc:HGNC:48729]",0,0,1,0,1,1,"no","no"]
[199085,0,"chrX","-",103675505,103686668,"ENST00000441076",4,1828,"ENSG00000123562","MORF4L2","GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0016569(covalent chromatin modification);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0006281(DNA repair);GO:0006974(cellular response to DNA damage stimulus);GO:0006325(chromatin organization);GO:0005730(nucleolus);GO:0040008(regulation of growth);GO:0006338(chromatin remodeling);GO:0006342(chromatin silencing);GO:0016575(histone deacetylation);GO:0043967(histone H4 acetylation);GO:0043968(histone H2A acetylation);GO:0035267(NuA4 histone acetyltransferase complex);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0051155(positive regulation of striated muscle cell differentiation)","NA","NA","NA","mortality factor 4 like 2 [Source:HGNC Symbol;Acc:HGNC:16849]",0,0,1,0,1,1,"no","no"]
[43293,0,"chr12","-",57107261,57111374,"ENST00000554825",5,644,"MSTRG.3477","STAT6","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0006355(regulation of transcription, DNA-templated);GO:0006366(transcription from RNA polymerase II promoter);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0031965(nuclear membrane);GO:0007165(signal transduction);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0004871(signal transducer activity);GO:0005515(protein binding);GO:0042802(identical protein binding);GO:0001228(transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0019903(protein phosphatase binding);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0000977(RNA polymerase II regulatory region sequence-specific DNA binding);GO:0032481(positive regulation of type I interferon production);GO:0000979(RNA polymerase II core promoter sequence-specific DNA binding);GO:0043565(sequence-specific DNA binding);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0002296(T-helper 1 cell lineage commitment);GO:0002829(negative regulation of type 2 immune response);GO:0019221(cytokine-mediated signaling pathway);GO:0033598(mammary gland epithelial cell proliferation);GO:0034097(response to cytokine);GO:0035771(interleukin-4-mediated signaling pathway);GO:0042127(regulation of cell proliferation);GO:0048295(positive regulation of isotype switching to IgE isotypes);GO:0060443(mammary gland morphogenesis);GO:0070301(cellular response to hydrogen peroxide);GO:1902170(cellular response to reactive nitrogen species);GO:0000790(nuclear chromatin);GO:0045121(membrane raft)","04630(Jak-STAT signaling pathway);04217(Necroptosis);04658(Th1 and Th2 cell differentiation);04659(Th17 cell differentiation);05200(Pathways in cancer);05321(Inflammatiory bowel disease (IBD));05161(Hepatitis B)","NA","NA","signal transducer and activator of transcription 6 [Source:HGNC Symbol;Acc:HGNC:11368]",{"v":0.297582,"d":"0.30"},{"v":0.167321,"d":"0.17"},{"v":1.77850957142259,"d":"1.78"},{"v":0.830668738586862,"d":"0.83"},1,1,"up","no"]
[3092,0,"chr1","+",26410778,26429722,"ENST00000326279",4,4008,"ENSG00000131914","LIN28A","GO:0051897(positive regulation of protein kinase B signaling);GO:0071333(cellular response to glucose stimulus);GO:0032008(positive regulation of TOR signaling);GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0005783(endoplasmic reticulum);GO:0005730(nucleolus);GO:0031047(gene silencing by RNA);GO:0000932(P-body);GO:0005515(protein binding);GO:0005829(cytosol);GO:0017148(negative regulation of translation);GO:0010494(cytoplasmic stress granule);GO:0035019(somatic stem cell population maintenance);GO:0019827(stem cell population maintenance);GO:0005791(rough endoplasmic reticulum);GO:1903800(positive regulation of production of miRNAs involved in gene silencing by miRNA);GO:0035198(miRNA binding);GO:0002151(G-quadruplex RNA binding);GO:1990825(sequence-specific mRNA binding);GO:0031054(pre-miRNA processing);GO:0010587(miRNA catabolic process);GO:0031123(RNA 3'-end processing);GO:0003729(mRNA binding);GO:0031369(translation initiation factor binding);GO:0007281(germ cell development);GO:0010586(miRNA metabolic process);GO:0045666(positive regulation of neuron differentiation);GO:0045686(negative regulation of glial cell differentiation);GO:0045727(positive regulation of translation);GO:0048863(stem cell differentiation);GO:0060964(regulation of gene silencing by miRNA);GO:1901724(positive regulation of cell proliferation involved in kidney development)","NA","NA","NA","lin-28 homolog A [Source:HGNC Symbol;Acc:HGNC:15986]",{"v":0.024709,"d":"0.02"},{"v":0.005236,"d":"0.01"},{"v":4.71906035141329,"d":"4.72"},{"v":2.23849962202104,"d":"2.24"},1,1,"up","no"]
[87070,0,"chr17","-",64854364,64863585,"ENST00000334962",5,2654,"ENSG00000176809","LRRC37A3","GO:0016020(membrane);GO:0016021(integral component of membrane)","NA","NA","NA","leucine rich repeat containing 37 member A3 [Source:HGNC Symbol;Acc:HGNC:32427]",{"v":0.125724,"d":"0.13"},{"v":0.409733,"d":"0.41"},{"v":0.306843725059978,"d":"0.31"},{"v":-1.70442401415731,"d":"-1.70"},1,1,"down","no"]
[106042,0,"chr19","-",56222058,56314842,"ENST00000593106",5,849,"ENSG00000131848","ZSCAN5A","GO:0005634(nucleus);GO:0003676(nucleic acid binding);GO:0046872(metal ion binding);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0000981(RNA polymerase II transcription factor activity, sequence-specific DNA binding)","NA","NA","NA","zinc finger and SCAN domain containing 5A [Source:HGNC Symbol;Acc:HGNC:23710]",0,0,1,0,1,1,"no","no"]
[71456,0,"chr16","+",29113050,29116326,"ENST00000641769",2,292,"ENSG00000284649","AC009093.8","NA","NA","NA","NA","NA",{"v":0.076846,"d":"0.08"},{"v":0.103341,"d":"0.10"},{"v":0.743615796247375,"d":"0.74"},{"v":-0.427370677876738,"d":"-0.43"},1,1,"down","no"]
[45996,0,"chr12","+",104064814,104079473,"ENST00000550444",4,746,"ENSG00000111727","HCFC2","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0005886(plasma membrane);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0003713(transcription coactivator activity);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0016032(viral process)","05168(Herpes simplex infection)","NA","NA","host cell factor C2 [Source:HGNC Symbol;Acc:HGNC:24972]",{"v":0.000485,"d":"0.00"},0,"inf","inf",1,1,"up","no"]
[48073,0,"chr12","-",123575891,123585115,"ENST00000498967",3,8279,"MSTRG.3837","AC055713.1","NA","NA","NA","NA","NA",{"v":0.060618,"d":"0.06"},{"v":0.047326,"d":"0.05"},{"v":1.28086041499387,"d":"1.28"},{"v":0.357113262901577,"d":"0.36"},1,1,"up","no"]
[53530,0,"chr14","+",24161290,24163586,"ENST00000560365",4,623,"MSTRG.4286","IRF9","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0005515(protein binding);GO:0000975(regulatory region DNA binding);GO:0051607(defense response to virus);GO:0001047(core promoter binding);GO:0005654(nucleoplasm);GO:0007166(cell surface receptor signaling pathway);GO:0006366(transcription from RNA polymerase II promoter);GO:0060333(interferon-gamma-mediated signaling pathway);GO:0060337(type I interferon signaling pathway)","04630(Jak-STAT signaling pathway);04217(Necroptosis);04621(NOD-like receptor signaling pathway);04380(Osteoclast differentiation);05203(Viral carcinogenesis);05162(Measles);05164(Influenza A);05160(Hepatitis C);05168(Herpes simplex infection);05167(Kaposi's sarcoma-associated herpesvirus infection);05165(Human papillomavirus infection)","NA","NA","interferon regulatory factor 9 [Source:HGNC Symbol;Acc:HGNC:6131]",0,{"v":1.207401,"d":"1.21"},"-inf","-inf",1,1,"down","no"]
[129796,0,"chr22","+",26657226,26665872,"ENST00000439738",3,628,"ENSG00000225783","MIAT","NA","NA","NA","NA","myocardial infarction associated transcript (non-protein coding) [Source:HGNC Symbol;Acc:HGNC:33425]",{"v":0.163203,"d":"0.16"},0,"inf","inf",1,1,"up","no"]
[54742,0,"chr14","-",49650119,49654320,"ENST00000554377",4,676,"ENSG00000100479","POLE2","GO:0005634(nucleus);GO:0043231(intracellular membrane-bounded organelle);GO:0005654(nucleoplasm);GO:0016740(transferase activity);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0016604(nuclear body);GO:0006260(DNA replication);GO:0016779(nucleotidyltransferase activity);GO:0003887(DNA-directed DNA polymerase activity);GO:0008622(epsilon DNA polymerase complex);GO:0006261(DNA-dependent DNA replication);GO:0000082(G1/S transition of mitotic cell cycle);GO:0006281(DNA repair);GO:0042276(error-prone translesion synthesis);GO:0006270(DNA replication initiation);GO:0032201(telomere maintenance via semi-conservative replication)","00230(Purine metabolism);00240(Pyrimidine metabolism);03030(DNA replication);03410(Base excision repair);03420(Nucleotide excision repair);05166(HTLV-I infection)","NA","NA","DNA polymerase epsilon 2, accessory subunit [Source:HGNC Symbol;Acc:HGNC:9178]",0,0,1,0,1,1,"no","no"]
[182558,0,"chr8","+",28316986,28339376,"ENST00000518479",3,554,"ENSG00000168081","PNOC","GO:0005576(extracellular region);GO:0001515(opioid peptide activity);GO:0007218(neuropeptide signaling pathway);GO:0007268(chemical synaptic transmission);GO:0005886(plasma membrane);GO:0007165(signal transduction);GO:0005184(neuropeptide hormone activity);GO:0030425(dendrite);GO:0043679(axon terminus);GO:0043025(neuronal cell body);GO:0007600(sensory perception);GO:0031628(opioid receptor binding);GO:0007565(female pregnancy)","NA","NA","NA","prepronociceptin [Source:HGNC Symbol;Acc:HGNC:9163]",0,0,1,0,1,1,"no","no"]
[81498,0,"chr17","-",29086572,29091093,"ENST00000529889",5,698,"MSTRG.6598","MYO18A","GO:0003723(RNA binding);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0003677(DNA binding);GO:0051015(actin filament binding);GO:0006259(DNA metabolic process);GO:0016459(myosin complex);GO:0005794(Golgi apparatus);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0000139(Golgi membrane);GO:0005802(trans-Golgi network);GO:0009986(cell surface);GO:0043066(negative regulation of apoptotic process);GO:0016477(cell migration);GO:0050714(positive regulation of protein secretion);GO:0007030(Golgi organization);GO:0005793(endoplasmic reticulum-Golgi intermediate compartment);GO:0043030(regulation of macrophage activation);GO:0043531(ADP binding);GO:0031032(actomyosin structure organization);GO:0042641(actomyosin);GO:0048194(Golgi vesicle budding);GO:0090161(Golgi ribbon formation);GO:0090164(asymmetric Golgi ribbon formation);GO:1903028(positive regulation of opsonization);GO:0003774(motor activity);GO:0008094(DNA-dependent ATPase activity)","NA","NA","NA","myosin XVIIIA [Source:HGNC Symbol;Acc:HGNC:31104]",0,{"v":0.053055,"d":"0.05"},"-inf","-inf",1,1,"down","no"]
[198567,0,"chrX","-",81114985,81121638,"ENST00000373250",5,572,"MSTRG.15381","HMGN5","GO:0005634(nucleus);GO:0003723(RNA binding);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0016569(covalent chromatin modification);GO:0003677(DNA binding);GO:0031492(nucleosomal DNA binding);GO:0000785(chromatin);GO:0045893(positive regulation of transcription, DNA-templated);GO:0003682(chromatin binding);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0010628(positive regulation of gene expression);GO:0043066(negative regulation of apoptotic process);GO:0008284(positive regulation of cell proliferation);GO:0006325(chromatin organization);GO:0006749(glutathione metabolic process);GO:0071157(negative regulation of cell cycle arrest);GO:0005654(nucleoplasm)","NA","NA","NA","high mobility group nucleosome binding domain 5 [Source:HGNC Symbol;Acc:HGNC:8013]",{"v":0.647697,"d":"0.65"},{"v":0.763276,"d":"0.76"},{"v":0.848575089482704,"d":"0.85"},{"v":-0.236885766962533,"d":"-0.24"},1,1,"down","no"]
[195844,0,"chrX","-",15561033,15602069,"ENST00000427411",19,3507,"ENSG00000130234","ACE2","GO:0005615(extracellular space);GO:1903779(regulation of cardiac conduction);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0046872(metal ion binding);GO:0016787(hydrolase activity);GO:0005886(plasma membrane);GO:0008233(peptidase activity);GO:0006508(proteolysis);GO:0005576(extracellular region);GO:0004180(carboxypeptidase activity);GO:0005515(protein binding);GO:0070062(extracellular exosome);GO:0016032(viral process);GO:0002003(angiotensin maturation);GO:0046813(receptor-mediated virion attachment to host cell);GO:0009986(cell surface);GO:0046718(viral entry into host cell);GO:0004175(endopeptidase activity);GO:0001618(virus receptor activity);GO:0050727(regulation of inflammatory response);GO:0045121(membrane raft);GO:0008270(zinc ion binding);GO:0019229(regulation of vasoconstriction);GO:0042127(regulation of cell proliferation);GO:1903598(positive regulation of gap junction assembly);GO:2000379(positive regulation of reactive oxygen species metabolic process);GO:0032800(receptor biosynthetic process);GO:0003081(regulation of systemic arterial blood pressure by renin-angiotensin);GO:0097746(regulation of blood vessel diameter);GO:0004181(metallocarboxypeptidase activity);GO:0001817(regulation of cytokine production);GO:0002005(angiotensin catabolic process in blood);GO:0003051(angiotensin-mediated drinking behavior);GO:0015827(tryptophan transport);GO:0060452(positive regulation of cardiac muscle contraction)","04614(Renin-angiotensin system);04974(Protein digestion and absorption)","K09708","EC:3.4.17.23","angiotensin I converting enzyme 2 [Source:HGNC Symbol;Acc:HGNC:13557]",0,{"v":0.004683,"d":"0.00"},"-inf","-inf",1,1,"down","no"]
[64279,0,"chr15","-",72202690,72206854,"ENST00000570166",2,626,"MSTRG.5254","PKM","GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0005829(cytosol);GO:0016740(transferase activity);GO:0000287(magnesium ion binding);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0003824(catalytic activity);GO:0006096(glycolytic process);GO:0005739(mitochondrion);GO:0005515(protein binding);GO:0008152(metabolic process);GO:0004743(pyruvate kinase activity);GO:0030955(potassium ion binding);GO:0005576(extracellular region);GO:0045296(cadherin binding);GO:0070062(extracellular exosome);GO:0031012(extracellular matrix);GO:0043312(neutrophil degranulation);GO:0034774(secretory granule lumen);GO:1904813(ficolin-1-rich granule lumen);GO:0031982(vesicle);GO:0012501(programmed cell death);GO:1903561(extracellular vesicle);GO:0061621(canonical glycolysis);GO:0023026(MHC class II protein complex binding);GO:0032869(cellular response to insulin stimulus);GO:0042802(identical protein binding);GO:0043531(ADP binding);GO:0070324(thyroid hormone binding);GO:0001666(response to hypoxia);GO:0001889(liver development);GO:0006006(glucose metabolic process);GO:0006754(ATP biosynthetic process);GO:0007584(response to nutrient);GO:0009629(response to gravity);GO:0010033(response to organic substance);GO:0014870(response to muscle inactivity);GO:0031100(animal organ regeneration);GO:0032868(response to insulin);GO:0042866(pyruvate biosynthetic process);GO:0043403(skeletal muscle tissue regeneration);GO:0051289(protein homotetramerization);GO:0005929(cilium);GO:0043209(myelin sheath);GO:1902912(pyruvate kinase complex)","00010(Glycolysis / Gluconeogenesis);00620(Pyruvate metabolism);00230(Purine metabolism);04922(Glucagon signaling pathway);05230(Central carbon metabolism in cancer);05203(Viral carcinogenesis);04930(Type II diabetes mellitus);05165(Human papillomavirus infection)","NA","NA","pyruvate kinase, muscle [Source:HGNC Symbol;Acc:HGNC:9021]",{"v":0.237807,"d":"0.24"},{"v":0.001483,"d":"0.00"},{"v":160.355360755226,"d":"160.36"},{"v":7.3251287743351,"d":"7.33"},1,1,"up","no"]
[151988,0,"chr4","+",163494668,163516102,"ENST00000508652",5,1195,"ENSG00000198498","TMA16","GO:0005634(nucleus);GO:0005730(nucleolus);GO:0005515(protein binding);GO:0005840(ribosome)","NA","NA","NA","translation machinery associated 16 homolog [Source:HGNC Symbol;Acc:HGNC:25638]",{"v":0.238682,"d":"0.24"},{"v":0.006904,"d":"0.01"},{"v":34.5715527230591,"d":"34.57"},{"v":5.11151349616055,"d":"5.11"},1,1,"up","no"]
[41177,0,"chr12","-",49101920,49103778,"ENST00000552141",5,756,"ENSG00000139636","LMBR1L","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005886(plasma membrane);GO:0006897(endocytosis)","NA","NA","NA","limb development membrane protein 1 like [Source:HGNC Symbol;Acc:HGNC:18268]",{"v":7.365E-3,"d":"0.01"},{"v":0.372117,"d":"0.37"},{"v":0.0197921621425519,"d":"0.02"},{"v":-5.65892696536552,"d":"-5.66"},1,1,"down","no"]
[180481,0,"chr7","+",155297776,155310233,"ENST00000344756",6,2623,"MSTRG.14152","INSIG1","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0006629(lipid metabolic process);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0008202(steroid metabolic process);GO:0005515(protein binding);GO:0008203(cholesterol metabolic process);GO:0006641(triglyceride metabolic process);GO:0006695(cholesterol biosynthetic process);GO:0006991(response to sterol depletion);GO:0010894(negative regulation of steroid biosynthetic process);GO:0016126(sterol biosynthetic process);GO:0042472(inner ear morphogenesis);GO:0042474(middle ear morphogenesis);GO:0045599(negative regulation of fat cell differentiation);GO:0045717(negative regulation of fatty acid biosynthetic process);GO:0060021(palate development);GO:0060363(cranial suture morphogenesis);GO:0008283(cell proliferation);GO:0008152(metabolic process);GO:0032933(SREBP signaling pathway);GO:1901303(negative regulation of cargo loading into COPII-coated vesicle);GO:0032937(SREBP-SCAP-Insig complex)","NA","NA","NA","insulin induced gene 1 [Source:HGNC Symbol;Acc:HGNC:6083]",0,{"v":0.004236,"d":"0.00"},"-inf","-inf",1,1,"down","no"]
[65926,0,"chr15","-",84645469,84654266,"ENST00000559224",6,788,"ENSG00000177082","WDR73","GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005856(cytoskeleton);GO:0000922(spindle pole);GO:0005819(spindle);GO:0032154(cleavage furrow)","NA","NA","NA","WD repeat domain 73 [Source:HGNC Symbol;Acc:HGNC:25928]",{"v":0.037023,"d":"0.04"},0,"inf","inf",1,1,"up","no"]
[116006,0,"chr2","-",167815053,167941144,"ENST00000436982",5,643,"ENSG00000235335","AC016723.1","NA","NA","NA","NA","NA",0,{"v":0.016449,"d":"0.02"},"-inf","-inf",1,1,"down","no"]
[52081,0,"chr13","+",114235061,114272675,"ENST00000252457",19,2034,"ENSG00000130177","CDC16","GO:0005737(cytoplasm);GO:0016567(protein ubiquitination);GO:0051301(cell division);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0007049(cell cycle);GO:0005815(microtubule organizing center);GO:0005819(spindle);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0031145(anaphase-promoting complex-dependent catabolic process);GO:0043161(proteasome-mediated ubiquitin-dependent protein catabolic process);GO:0051437(positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition);GO:0051436(negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle);GO:0008283(cell proliferation);GO:0042787(protein ubiquitination involved in ubiquitin-dependent protein catabolic process);GO:0051439(regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle);GO:0070979(protein K11-linked ubiquitination);GO:0005680(anaphase-promoting complex);GO:0007088(regulation of mitotic nuclear division);GO:0000278(mitotic cell cycle);GO:0005813(centrosome);GO:0005876(spindle microtubule);GO:0005634(nucleus)","04120(Ubiquitin mediated proteolysis);04110(Cell cycle);04114(Oocyte meiosis);04914(Progesterone-mediated oocyte maturation);05166(HTLV-I infection)","K03353","NA","cell division cycle 16 [Source:HGNC Symbol;Acc:HGNC:1720]",0,{"v":0.411842,"d":"0.41"},"-inf","-inf",1,1,"down","no"]
[108565,0,"chr2","+",32201600,32203999,"ENST00000438163",1,2400,"ENSG00000229816","DDX50P1","NA","NA","NA","NA","DEAD-box helicase 50 pseudogene 1 [Source:HGNC Symbol;Acc:HGNC:18974]",{"v":0.021418,"d":"0.02"},0,"inf","inf",1,1,"up","no"]
[84170,0,"chr17","-",44322473,44324806,"ENST00000591151",4,636,"MSTRG.6897","SLC25A39","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005743(mitochondrial inner membrane);GO:0005739(mitochondrion);GO:0055085(transmembrane transport);GO:0006783(heme biosynthetic process);GO:0006839(mitochondrial transport);GO:0022857(transmembrane transporter activity)","NA","NA","NA","solute carrier family 25 member 39 [Source:HGNC Symbol;Acc:HGNC:24279]",{"v":1.097413,"d":"1.10"},{"v":0.067285,"d":"0.07"},{"v":16.3099204874786,"d":"16.31"},{"v":4.02767784366923,"d":"4.03"},1,1,"up","no"]
[110233,0,"chr2","+",63840971,63882601,"ENST00000497510",5,722,"MSTRG.8759","UGP2","GO:0008152(metabolic process);GO:0070569(uridylyltransferase activity);GO:0003983(UTP:glucose-1-phosphate uridylyltransferase activity);GO:0006011(UDP-glucose metabolic process);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0016740(transferase activity);GO:0005515(protein binding);GO:0016779(nucleotidyltransferase activity);GO:0042802(identical protein binding);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0005978(glycogen biosynthetic process);GO:0006065(UDP-glucuronate biosynthetic process);GO:0005977(glycogen metabolic process);GO:0005536(glucose binding);GO:0032557(pyrimidine ribonucleotide binding);GO:0019255(glucose 1-phosphate metabolic process)","00040(Pentose and glucuronate interconversions);00052(Galactose metabolism);00500(Starch and sucrose metabolism);00520(Amino sugar and nucleotide sugar metabolism)","NA","NA","UDP-glucose pyrophosphorylase 2 [Source:HGNC Symbol;Acc:HGNC:12527]",{"v":0.012853,"d":"0.01"},0,"inf","inf",1,1,"up","no"]
[176941,0,"chr7","-",100575063,100585120,"ENST00000497245",18,2014,"MSTRG.13826","LRCH4","GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0007165(signal transduction);GO:0045199(maintenance of epithelial cell apical/basal polarity);GO:0016323(basolateral plasma membrane);GO:0007399(nervous system development);GO:0016605(PML body);GO:0016020(membrane);GO:0016021(integral component of membrane)","NA","NA","NA","leucine rich repeats and calponin homology domain containing 4 [Source:HGNC Symbol;Acc:HGNC:6691]",0,{"v":0.000789,"d":"0.00"},"-inf","-inf",1,1,"down","no"]
[4294,0,"chr1","-",36355253,36362656,"ENST00000473733",5,629,"MSTRG.422","STK40","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0005515(protein binding);GO:0003016(respiratory system process);GO:0005977(glycogen metabolic process);GO:0010468(regulation of gene expression);GO:0030324(lung development);GO:0035264(multicellular organism growth);GO:0043066(negative regulation of apoptotic process);GO:0043408(regulation of MAPK cascade);GO:0048286(lung alveolus development);GO:0060425(lung morphogenesis)","NA","NA","NA","serine/threonine kinase 40 [Source:HGNC Symbol;Acc:HGNC:21373]",{"v":0.251326,"d":"0.25"},{"v":0.123214,"d":"0.12"},{"v":2.03975197623647,"d":"2.04"},{"v":1.02839373827151,"d":"1.03"},1,1,"up","no"]
[132188,0,"chr22","+",45413691,45432496,"ENST00000614167",7,1479,"ENSG00000128408","RIBC2","NA","NA","NA","NA","RIB43A domain with coiled-coils 2 [Source:HGNC Symbol;Acc:HGNC:13241]",{"v":0.034755,"d":"0.03"},{"v":0.082981,"d":"0.08"},{"v":0.418830816692978,"d":"0.42"},{"v":-1.25556049823829,"d":"-1.26"},1,1,"down","no"]
[10043,0,"chr1","+",145836537,145840407,"ENST00000489436",5,820,"MSTRG.850","POLR3C","GO:0005654(nucleoplasm);GO:0003677(DNA binding);GO:0006351(transcription, DNA-templated);GO:0003899(DNA-directed 5'-3' RNA polymerase activity);GO:0005634(nucleus);GO:0005515(protein binding);GO:0002376(immune system process);GO:0045087(innate immune response);GO:0051607(defense response to virus);GO:0005829(cytosol);GO:0032728(positive regulation of interferon-beta production);GO:0045089(positive regulation of innate immune response);GO:0001056(RNA polymerase III activity);GO:0006383(transcription from RNA polymerase III promoter);GO:0032481(positive regulation of type I interferon production);GO:0005666(DNA-directed RNA polymerase III complex);GO:0006359(regulation of transcription from RNA polymerase III promoter)","00230(Purine metabolism);00240(Pyrimidine metabolism);03020(RNA polymerase);04623(Cytosolic DNA-sensing pathway);05169(Epstein-Barr virus infection)","NA","NA","RNA polymerase III subunit C [Source:HGNC Symbol;Acc:HGNC:30076]",{"v":0.158307,"d":"0.16"},0,"inf","inf",1,1,"up","no"]
[133462,0,"chr3","+",12484511,12533317,"ENST00000284995",12,2381,"MSTRG.10663","TSEN2","GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0005813(centrosome);GO:0000213(tRNA-intron endonuclease activity);GO:0006388(tRNA splicing, via endonucleolytic cleavage and ligation);GO:0090501(RNA phosphodiester bond hydrolysis);GO:0090502(RNA phosphodiester bond hydrolysis, endonucleolytic);GO:0000214(tRNA-intron endonuclease complex);GO:0006397(mRNA processing);GO:0005634(nucleus);GO:0008033(tRNA processing);GO:0016829(lyase activity);GO:0005515(protein binding);GO:0005730(nucleolus);GO:0000379(tRNA-type intron splice site recognition and cleavage);GO:0090305(nucleic acid phosphodiester bond hydrolysis);GO:0004519(endonuclease activity)","NA","NA","NA","tRNA splicing endonuclease subunit 2 [Source:HGNC Symbol;Acc:HGNC:28422]",0,{"v":0.084679,"d":"0.08"},"-inf","-inf",1,1,"down","no"]
[5766,0,"chr1","-",46843178,46900434,"ENST00000423332",12,1512,"ENSG00000154198","CYP4Z2P","NA","NA","NA","NA","cytochrome P450 family 4 subfamily Z member 2, pseudogene [Source:HGNC Symbol;Acc:HGNC:24426]",{"v":0.041243,"d":"0.04"},{"v":0.018569,"d":"0.02"},{"v":2.22106737034843,"d":"2.22"},{"v":1.15125315398057,"d":"1.15"},1,1,"up","no"]
[75397,0,"chr16","-",71749919,71808834,"ENST00000568327",16,1724,"MSTRG.6102","AP1G1","GO:0006810(transport);GO:0016020(membrane);GO:0008565(protein transporter activity);GO:0006886(intracellular protein transport);GO:0015031(protein transport);GO:0016192(vesicle-mediated transport);GO:0030117(membrane coat);GO:0043231(intracellular membrane-bounded organelle);GO:0005829(cytosol);GO:0005794(Golgi apparatus);GO:0030131(clathrin adaptor complex);GO:0005515(protein binding);GO:0031410(cytoplasmic vesicle);GO:0055037(recycling endosome);GO:0019886(antigen processing and presentation of exogenous peptide antigen via MHC class II);GO:0005737(cytoplasm);GO:0005215(transporter activity);GO:0030119(AP-type membrane coat adaptor complex);GO:0032588(trans-Golgi network membrane);GO:0030742(GTP-dependent protein binding);GO:0030665(clathrin-coated vesicle membrane);GO:0000139(Golgi membrane);GO:0017137(Rab GTPase binding);GO:0032438(melanosome organization);GO:0035646(endosome to melanosome transport);GO:0019894(kinesin binding);GO:0005765(lysosomal membrane);GO:0043323(positive regulation of natural killer cell degranulation);GO:0045954(positive regulation of natural killer cell mediated cytotoxicity);GO:0050690(regulation of defense response to virus by virus);GO:0090160(Golgi to lysosome transport);GO:0030136(clathrin-coated vesicle);GO:0030659(cytoplasmic vesicle membrane);GO:0030669(clathrin-coated endocytic vesicle membrane)","04142(Lysosome)","NA","NA","adaptor related protein complex 1 gamma 1 subunit [Source:HGNC Symbol;Acc:HGNC:555]",0,0,1,0,1,1,"no","no"]
[202096,0,"chrY","+",23462465,23472280,"ENST00000422655",2,198,"ENSG00000225189","REREP1Y","NA","NA","NA","NA","arginine-glutamic acid dipeptide repeats pseudogene 1, Y-linked [Source:HGNC Symbol;Acc:HGNC:38795]",{"v":0.0981,"d":"0.10"},0,"inf","inf",1,1,"up","no"]
[197093,0,"chrX","-",48905398,48911646,"ENST00000634665",4,486,"MSTRG.15288","SLC35A2","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005794(Golgi apparatus);GO:0005634(nucleus);GO:0000139(Golgi membrane);GO:0008643(carbohydrate transport);GO:0005351(sugar:proton symporter activity);GO:0015992(proton transport);GO:0005783(endoplasmic reticulum);GO:0006012(galactose metabolic process);GO:0005459(UDP-galactose transmembrane transporter activity);GO:0015785(UDP-galactose transport);GO:0072334(UDP-galactose transmembrane transport)","NA","NA","NA","solute carrier family 35 member A2 [Source:HGNC Symbol;Acc:HGNC:11022]",{"v":0.33891,"d":"0.34"},0,"inf","inf",1,1,"up","no"]
[132502,0,"chr22","-",50267138,50270767,"ENST00000495277",4,566,"ENSG00000185386","MAPK11","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0016740(transferase activity);GO:0004707(MAP kinase activity);GO:0016301(kinase activity);GO:0000165(MAPK cascade);GO:0016310(phosphorylation);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0005515(protein binding);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0098586(cellular response to virus);GO:0010628(positive regulation of gene expression);GO:0007165(signal transduction);GO:2001184(positive regulation of interleukin-12 secretion);GO:1901796(regulation of signal transduction by p53 class mediator);GO:0048010(vascular endothelial growth factor receptor signaling pathway);GO:0035556(intracellular signal transduction);GO:0006950(response to stress);GO:0000187(activation of MAPK activity);GO:0051149(positive regulation of muscle cell differentiation);GO:0051090(regulation of sequence-specific DNA binding transcription factor activity);GO:0007265(Ras protein signal transduction);GO:0060043(regulation of cardiac muscle cell proliferation);GO:0060044(negative regulation of cardiac muscle cell proliferation)","04015(Rap1 signaling pathway);04010(MAPK signaling pathway);04370(VEGF signaling pathway);04668(TNF signaling pathway);04068(FoxO signaling pathway);04071(Sphingolipid signaling pathway);04218(Cellular senescence);04550(Signaling pathways regulating pluripotency of stem cells);04611(Platelet activation);04620(Toll-like receptor signaling pathway);04621(NOD-like receptor signaling pathway);04622(RIG-I-like receptor signaling pathway);04660(T cell receptor signaling pathway);04658(Th1 and Th2 cell differentiation);04659(Th17 cell differentiation);04657(IL-17 signaling pathway);04664(Fc epsilon RI signaling pathway);04670(Leukocyte transendothelial migration);04912(GnRH signaling pathway);04914(Progesterone-mediated oocyte maturation);04917(Prolactin signaling pathway);04926(Relaxin signaling pathway);04261(Adrenergic signaling in cardiomyocytes);04728(Dopaminergic synapse);04723(Retrograde endocannabinoid signaling);04722(Neurotrophin signaling pathway);04750(Inflammatory mediator regulation of TRP channels);04380(Osteoclast differentiation);05205(Proteoglycans in cancer);05014(Amyotrophic lateral sclerosis (ALS));05418(Fluid shear stress and atherosclerosis);04933(AGE-RAGE signaling pathway in diabetic complications);05120(Epithelial cell signaling in Helicobacter pylori infection);05132(Salmonella infection);05131(Shigellosis);05133(Pertussis);05152(Tuberculosis);05164(Influenza A);05160(Hepatitis C);05167(Kaposi's sarcoma-associated herpesvirus infection);05169(Epstein-Barr virus infection);05145(Toxoplasmosis);05140(Leishmaniasis);05142(Chagas disease (American trypanosomiasis));01522(Endocrine resistance)","NA","NA","mitogen-activated protein kinase 11 [Source:HGNC Symbol;Acc:HGNC:6873]",0,0,1,0,1,1,"no","no"]
[112956,0,"chr2","-",101382926,101387466,"ENST00000486966",3,775,"ENSG00000175874","CREG2","GO:0005576(extracellular region);GO:0048037(cofactor binding);GO:0005783(endoplasmic reticulum);GO:0005794(Golgi apparatus)","NA","NA","NA","cellular repressor of E1A stimulated genes 2 [Source:HGNC Symbol;Acc:HGNC:14272]",0,{"v":0.048017,"d":"0.05"},"-inf","-inf",1,1,"down","no"]
[161770,0,"chr5","-",178150639,178153882,"ENST00000514354",4,472,"MSTRG.12587","NHP2","GO:0003723(RNA binding);GO:0005634(nucleus);GO:0030529(intracellular ribonucleoprotein complex);GO:0005515(protein binding);GO:0005730(nucleolus);GO:0042254(ribosome biogenesis);GO:0006364(rRNA processing);GO:0005654(nucleoplasm);GO:0000784(nuclear chromosome, telomeric region);GO:0005732(small nucleolar ribonucleoprotein complex);GO:0070034(telomerase RNA binding);GO:0007004(telomere maintenance via telomerase);GO:0005697(telomerase holoenzyme complex);GO:0015030(Cajal body);GO:0006412(translation);GO:0034513(box H/ACA snoRNA binding);GO:0031118(rRNA pseudouridine synthesis);GO:0031120(snRNA pseudouridine synthesis);GO:1904874(positive regulation of telomerase RNA localization to Cajal body);GO:0031429(box H/ACA snoRNP complex);GO:0072589(box H/ACA scaRNP complex);GO:0090661(box H/ACA telomerase RNP complex);GO:0000470(maturation of LSU-rRNA);GO:0030515(snoRNA binding);GO:0000469(cleavage involved in rRNA processing)","03008(Ribosome biogenesis in eukaryotes)","NA","NA","NHP2 ribonucleoprotein [Source:HGNC Symbol;Acc:HGNC:14377]",0,0,1,0,1,1,"no","no"]
[31256,0,"chr11","-",65538819,65546759,"ENST00000529189",12,1997,"MSTRG.2553","LTBP3","GO:0005509(calcium ion binding);GO:0005576(extracellular region);GO:0070062(extracellular exosome);GO:0031012(extracellular matrix);GO:0019838(growth factor binding);GO:2000741(positive regulation of mesenchymal stem cell differentiation);GO:0050431(transforming growth factor beta binding);GO:0036363(transforming growth factor beta activation);GO:1902462(positive regulation of mesenchymal stem cell proliferation)","NA","NA","NA","latent transforming growth factor beta binding protein 3 [Source:HGNC Symbol;Acc:HGNC:6716]",{"v":1.55241,"d":"1.55"},0,"inf","inf",1,1,"up","no"]
[31388,0,"chr11","+",65726939,65728214,"ENST00000534154",1,1276,"MSTRG.2560","KRT8P26","NA","NA","NA","NA","keratin 8 pseudogene 26 [Source:HGNC Symbol;Acc:HGNC:33378]",0,{"v":0.071034,"d":"0.07"},"-inf","-inf",1,1,"down","no"]
[29850,0,"chr11","+",61228377,61231566,"ENST00000537932",4,840,"ENSG00000229183","PGA4","GO:0016787(hydrolase activity);GO:0008233(peptidase activity);GO:0006508(proteolysis);GO:0005576(extracellular region);GO:0004190(aspartic-type endopeptidase activity);GO:0070062(extracellular exosome);GO:0044267(cellular protein metabolic process);GO:0006914(autophagy);GO:0030163(protein catabolic process);GO:0097486(multivesicular body lumen);GO:0007586(digestion)","04974(Protein digestion and absorption)","NA","NA","pepsinogen 4, group I (pepsinogen A) [Source:HGNC Symbol;Acc:HGNC:8886]",0,{"v":0.051847,"d":"0.05"},"-inf","-inf",1,1,"down","no"]
[9337,0,"chr1","-",112703001,112704921,"ENST00000414971",4,470,"MSTRG.813","RHOC","GO:0016020(membrane);GO:0005525(GTP binding);GO:0007264(small GTPase mediated signal transduction);GO:0000166(nucleotide binding);GO:0003924(GTPase activity);GO:0005622(intracellular);GO:0005886(plasma membrane);GO:0044319(wound healing, spreading of cells);GO:1902766(skeletal muscle satellite cell migration);GO:0005515(protein binding);GO:0004871(signal transducer activity);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0051056(regulation of small GTPase mediated signal transduction);GO:0032154(cleavage furrow);GO:0032420(stereocilium);GO:0043123(positive regulation of I-kappaB kinase/NF-kappaB signaling);GO:0000910(cytokinesis);GO:0043297(apical junction assembly);GO:0032464(positive regulation of protein homooligomerization);GO:0060193(positive regulation of lipase activity);GO:0005634(nucleus)","NA","NA","NA","ras homolog family member C [Source:HGNC Symbol;Acc:HGNC:669]",{"v":0.336214,"d":"0.34"},{"v":1.817E-3,"d":"0.00"},{"v":185.037974683544,"d":"185.04"},{"v":7.53167757005949,"d":"7.53"},1,1,"up","no"]
[65925,0,"chr15","-",84644955,84654231,"ENST00000560966",3,5071,"ENSG00000177082","WDR73","GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005856(cytoskeleton);GO:0000922(spindle pole);GO:0005819(spindle);GO:0032154(cleavage furrow)","NA","NA","NA","WD repeat domain 73 [Source:HGNC Symbol;Acc:HGNC:25928]",{"v":0.252706,"d":"0.25"},{"v":0.100326,"d":"0.10"},{"v":2.51884855371489,"d":"2.52"},{"v":1.33276438234498,"d":"1.33"},1,1,"up","no"]
[181519,0,"chr8","+",17131181,17149789,"ENST00000513892",3,2292,"ENSG00000249258","AC079193.2","NA","NA","NA","NA","NA",{"v":0.000673,"d":"0.00"},{"v":0.079623,"d":"0.08"},{"v":0.00845233161272497,"d":"0.01"},{"v":-6.88643491461489,"d":"-6.89"},1,1,"down","no"]
[190283,0,"chr9","+",37753803,37778965,"ENST00000377753",7,2027,"MSTRG.14785","TRMT10B","GO:0008168(methyltransferase activity);GO:0016740(transferase activity);GO:0032259(methylation);GO:0030488(tRNA methylation);GO:0005829(cytosol);GO:0009019(tRNA (guanine-N1-)-methyltransferase activity)","NA","NA","NA","tRNA methyltransferase 10B [Source:HGNC Symbol;Acc:HGNC:26454]",0,0,1,0,1,1,"no","no"]
[158103,0,"chr5","-",131677597,131797016,"ENST00000511848",13,1720,"MSTRG.12281","FNIP1","GO:0005737(cytoplasm);GO:0043547(positive regulation of GTPase activity);GO:0005515(protein binding);GO:0005085(guanyl-nucleotide exchange factor activity);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0001934(positive regulation of protein phosphorylation);GO:0033138(positive regulation of peptidyl-serine phosphorylation);GO:0009267(cellular response to starvation);GO:0032007(negative regulation of TOR signaling);GO:0043154(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process);GO:0051087(chaperone binding);GO:0001932(regulation of protein phosphorylation);GO:0002327(immature B cell differentiation);GO:0031929(TOR signaling);GO:0042030(ATPase inhibitor activity);GO:2000973(regulation of pro-B cell differentiation);GO:0002904(positive regulation of B cell apoptotic process);GO:0031334(positive regulation of protein complex assembly)","04150(mTOR signaling pathway)","NA","NA","folliculin interacting protein 1 [Source:HGNC Symbol;Acc:HGNC:29418]",{"v":0.041515,"d":"0.04"},0,"inf","inf",1,1,"up","no"]
[115757,0,"chr2","+",161624426,161983245,"ENST00000272716",25,3414,"MSTRG.9200","SLC4A10","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005215(transporter activity);GO:0015293(symporter activity);GO:0006811(ion transport);GO:0005886(plasma membrane);GO:0015297(antiporter activity);GO:0006814(sodium ion transport);GO:0035725(sodium ion transmembrane transport);GO:0006821(chloride transport);GO:0008509(anion transmembrane transporter activity);GO:0006820(anion transport);GO:0098656(anion transmembrane transport);GO:0005452(inorganic anion exchanger activity);GO:0005887(integral component of plasma membrane);GO:0007399(nervous system development);GO:0051453(regulation of intracellular pH);GO:0015701(bicarbonate transport);GO:0008510(sodium:bicarbonate symporter activity);GO:0015698(inorganic anion transport);GO:0015301(anion:anion antiporter activity);GO:0006885(regulation of pH);GO:0009416(response to light stimulus);GO:0009791(post-embryonic development);GO:0021860(pyramidal neuron development);GO:0030641(regulation of cellular pH);GO:0035264(multicellular organism growth);GO:0035641(locomotory exploration behavior);GO:0048854(brain morphogenesis);GO:1902600(hydrogen ion transmembrane transport);GO:0016323(basolateral plasma membrane);GO:0043025(neuronal cell body);GO:0097440(apical dendrite);GO:0097441(basilar dendrite);GO:0097442(CA3 pyramidal cell dendrite)","NA","NA","NA","solute carrier family 4 member 10 [Source:HGNC Symbol;Acc:HGNC:13811]",0,0,1,0,1,1,"no","no"]
[174018,0,"chr7","-",50458436,50561054,"ENST00000357936",15,1938,"ENSG00000132437","DDC","GO:0003824(catalytic activity);GO:0016829(lyase activity);GO:0030170(pyridoxal phosphate binding);GO:0019752(carboxylic acid metabolic process);GO:0016831(carboxy-lyase activity);GO:0006520(cellular amino acid metabolic process);GO:0005515(protein binding);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0019899(enzyme binding);GO:0042416(dopamine biosynthetic process);GO:0042423(catecholamine biosynthetic process);GO:0046219(indolalkylamine biosynthetic process);GO:0004058(aromatic-L-amino-acid decarboxylase activity);GO:0036468(L-dopa decarboxylase activity);GO:0016597(amino acid binding);GO:0019904(protein domain specific binding);GO:0007623(circadian rhythm);GO:0009636(response to toxic substance);GO:0010259(multicellular organism aging);GO:0015842(aminergic neurotransmitter loading into synaptic vesicle);GO:0033076(isoquinoline alkaloid metabolic process);GO:0035690(cellular response to drug);GO:0042427(serotonin biosynthetic process);GO:0046684(response to pyrethroid);GO:0052314(phytoalexin metabolic process);GO:0071312(cellular response to alkaloid);GO:0071363(cellular response to growth factor stimulus);GO:0005737(cytoplasm);GO:0008021(synaptic vesicle);GO:0030424(axon);GO:0043025(neuronal cell body)","00350(Tyrosine metabolism);00360(Phenylalanine metabolism);00380(Tryptophan metabolism);04728(Dopaminergic synapse);04726(Serotonergic synapse);05030(Cocaine addiction);05031(Amphetamine addiction);05034(Alcoholism)","K01593","EC:4.1.1.28","dopa decarboxylase [Source:HGNC Symbol;Acc:HGNC:2719]",{"v":0.060537,"d":"0.06"},0,"inf","inf",1,1,"up","no"]
[70597,0,"chr16","-",21532945,21550373,"ENST00000550637",5,576,"ENSG00000257639","AC005632.1","NA","NA","NA","NA","NA",{"v":0.160963,"d":"0.16"},{"v":0.057161,"d":"0.06"},{"v":2.81595843319746,"d":"2.82"},{"v":1.49362603828541,"d":"1.49"},1,1,"up","no"]
[37399,0,"chr12","+",1917951,1922867,"ENST00000544163",2,315,"ENSG00000256706","AC005342.2","NA","NA","NA","NA","NA",{"v":0.168022,"d":"0.17"},{"v":0.433547,"d":"0.43"},{"v":0.387551983983282,"d":"0.39"},{"v":-1.36753825674609,"d":"-1.37"},1,1,"down","no"]
[160423,0,"chr5","+",154955199,154966945,"ENST00000520040",3,2344,"ENSG00000082515","MRPL22","GO:0003723(RNA binding);GO:0030529(intracellular ribonucleoprotein complex);GO:0003735(structural constituent of ribosome);GO:0006412(translation);GO:0005840(ribosome);GO:0005739(mitochondrion);GO:0015934(large ribosomal subunit);GO:0005743(mitochondrial inner membrane);GO:0070125(mitochondrial translational elongation);GO:0070126(mitochondrial translational termination);GO:0005762(mitochondrial large ribosomal subunit)","03010(Ribosome)","NA","NA","mitochondrial ribosomal protein L22 [Source:HGNC Symbol;Acc:HGNC:14480]",{"v":3.127E-3,"d":"0.00"},{"v":0.00043,"d":"0.00"},{"v":7.27209302325581,"d":"7.27"},{"v":2.86237065433558,"d":"2.86"},1,1,"up","no"]
[158365,0,"chr5","-",133980729,134004635,"ENST00000425992",6,703,"MSTRG.12311","VDAC1","GO:0006810(transport);GO:0005634(nucleus);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0055085(transmembrane transport);GO:0008308(voltage-gated anion channel activity);GO:0098656(anion transmembrane transport);GO:1903959(regulation of anion transmembrane transport);GO:0005741(mitochondrial outer membrane);GO:0005739(mitochondrion);GO:0006811(ion transport);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0006915(apoptotic process);GO:0045121(membrane raft);GO:0006820(anion transport);GO:0070062(extracellular exosome);GO:0044325(ion channel binding);GO:0016032(viral process);GO:1903146(regulation of mitophagy);GO:0030855(epithelial cell differentiation);GO:0042645(mitochondrial nucleoid);GO:0015288(porin activity);GO:0016236(macroautophagy);GO:0019901(protein kinase binding);GO:0046930(pore complex);GO:0005253(anion channel activity);GO:0032403(protein complex binding);GO:0001662(behavioral fear response);GO:0006851(mitochondrial calcium ion transmembrane transport);GO:0007268(chemical synaptic transmission);GO:0007270(neuron-neuron synaptic transmission);GO:0007612(learning);GO:2000378(negative regulation of reactive oxygen species metabolic process);GO:0005743(mitochondrial inner membrane);GO:0008021(synaptic vesicle);GO:0043209(myelin sheath);GO:0043234(protein complex)","04020(Calcium signaling pathway);04022(cGMP - PKG signaling pathway);04217(Necroptosis);04218(Cellular senescence);04621(NOD-like receptor signaling pathway);04979(Cholesterol metabolism);05012(Parkinson's disease);05016(Huntington's disease);05166(HTLV-I infection);05164(Influenza A)","NA","NA","voltage dependent anion channel 1 [Source:HGNC Symbol;Acc:HGNC:12669]",{"v":0.217831,"d":"0.22"},{"v":7.6e-05,"d":"0.00"},{"v":2866.19736842105,"d":"2866.20"},{"v":11.4849222427054,"d":"11.48"},1,1,"up","no"]
[126481,0,"chr21","-",30319124,30320316,"ENST00000360542",1,1193,"ENSG00000197683","KRTAP26-1","GO:0005515(protein binding);GO:0005882(intermediate filament);GO:0005829(cytosol);GO:0031424(keratinization)","NA","NA","NA","keratin associated protein 26-1 [Source:HGNC Symbol;Acc:HGNC:33760]",0,{"v":0.076486,"d":"0.08"},"-inf","-inf",1,1,"down","no"]
[143382,0,"chr3","+",184164647,184165478,"ENST00000467873",2,617,"MSTRG.11378","DVL3","GO:0001934(positive regulation of protein phosphorylation);GO:0043507(positive regulation of JUN kinase activity);GO:0005737(cytoplasm);GO:0035556(intracellular signal transduction);GO:0005515(protein binding);GO:0007275(multicellular organism development);GO:0016055(Wnt signaling pathway);GO:0005829(cytosol);GO:0090090(negative regulation of canonical Wnt signaling pathway);GO:0046982(protein heterodimerization activity);GO:0002020(protease binding);GO:0045893(positive regulation of transcription, DNA-templated);GO:0000790(nuclear chromatin);GO:0050821(protein stabilization);GO:0060070(canonical Wnt signaling pathway);GO:0005102(receptor binding);GO:0005109(frizzled binding);GO:0060071(Wnt signaling pathway, planar cell polarity pathway);GO:0090179(planar cell polarity pathway involved in neural tube closure);GO:1903827(regulation of cellular protein localization);GO:1904886(beta-catenin destruction complex disassembly);GO:0035567(non-canonical Wnt signaling pathway);GO:0008013(beta-catenin binding);GO:0038031(non-canonical Wnt signaling pathway via JNK cascade);GO:0043547(positive regulation of GTPase activity);GO:0048365(Rac GTPase binding);GO:0042493(response to drug)","04310(Wnt signaling pathway);04330(Notch signaling pathway);04390(Hippo signaling pathway);04150(mTOR signaling pathway);04550(Signaling pathways regulating pluripotency of stem cells);04916(Melanogenesis);05200(Pathways in cancer);05225(Hepatocellular carcinoma);05226(Gastric cancer);05217(Basal cell carcinoma);05224(Breast cancer);05166(HTLV-I infection);05165(Human papillomavirus infection)","NA","NA","dishevelled segment polarity protein 3 [Source:HGNC Symbol;Acc:HGNC:3087]",{"v":0.066603,"d":"0.07"},{"v":0.4456,"d":"0.45"},{"v":0.149468132854578,"d":"0.15"},{"v":-2.74209016546928,"d":"-2.74"},1,1,"down","no"]
[189028,0,"chr9","+",7013788,7169829,"ENST00000420847",9,1064,"ENSG00000107077","KDM4C","GO:0008284(positive regulation of cell proliferation);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0016569(covalent chromatin modification);GO:0008270(zinc ion binding);GO:0051213(dioxygenase activity);GO:0005654(nucleoplasm);GO:0032454(histone demethylase activity (H3-K9 specific));GO:0033169(histone H3-K9 demethylation);GO:0000790(nuclear chromatin);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0032452(histone demethylase activity);GO:0019899(enzyme binding);GO:0050681(androgen receptor binding);GO:0051864(histone demethylase activity (H3-K36 specific));GO:0070544(histone H3-K36 demethylation);GO:0003682(chromatin binding);GO:0001825(blastocyst formation);GO:0010468(regulation of gene expression);GO:0010628(positive regulation of gene expression);GO:0045666(positive regulation of neuron differentiation);GO:1900113(negative regulation of histone H3-K9 trimethylation);GO:2000036(regulation of stem cell population maintenance);GO:2000736(regulation of stem cell differentiation);GO:0005721(pericentric heterochromatin)","NA","NA","NA","lysine demethylase 4C [Source:HGNC Symbol;Acc:HGNC:17071]",{"v":0.080969,"d":"0.08"},{"v":0.163149,"d":"0.16"},{"v":0.496288668640323,"d":"0.50"},{"v":-1.01074857977084,"d":"-1.01"},1,1,"down","no"]
[99819,0,"chr19","+",34428373,34450364,"ENST00000590048",8,847,"MSTRG.8066","UBA2","GO:0008641(small protein activating enzyme activity);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0005654(nucleoplasm);GO:0043085(positive regulation of catalytic activity);GO:0016874(ligase activity);GO:0005515(protein binding);GO:0016925(protein sumoylation);GO:0046982(protein heterodimerization activity);GO:0008047(enzyme activator activity);GO:0000287(magnesium ion binding);GO:0032183(SUMO binding);GO:0044388(small protein activating enzyme binding);GO:0019948(SUMO activating enzyme activity);GO:0031510(SUMO activating enzyme complex);GO:0008134(transcription factor binding);GO:0044390(ubiquitin-like protein conjugating enzyme binding);GO:0016881(acid-amino acid ligase activity)","04120(Ubiquitin mediated proteolysis)","NA","NA","ubiquitin like modifier activating enzyme 2 [Source:HGNC Symbol;Acc:HGNC:30661]",{"v":0.24399,"d":"0.24"},{"v":0.379294,"d":"0.38"},{"v":0.64327408290139,"d":"0.64"},{"v":-0.636494530286204,"d":"-0.64"},1,1,"down","no"]
[41654,0,"chr12","-",51094883,51173134,"ENST00000549867",13,1727,"ENSG00000135457","TFCP2","GO:0005634(nucleus);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0006366(transcription from RNA polymerase II promoter);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:0001077(transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0005575(cellular_component);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0043565(sequence-specific DNA binding);GO:0006357(regulation of transcription from RNA polymerase II promoter)","NA","NA","NA","transcription factor CP2 [Source:HGNC Symbol;Acc:HGNC:11748]",0,{"v":0.104782,"d":"0.10"},"-inf","-inf",1,1,"down","no"]
[156685,0,"chr5","-",91280097,91281142,"ENST00000440769",1,1046,"MSTRG.12201","AC123595.1","NA","NA","NA","NA","NA",0,{"v":0.15964,"d":"0.16"},"-inf","-inf",1,1,"down","no"]
[6155,0,"chr1","-",52911600,52912225,"ENST00000487040",2,557,"MSTRG.567","ECHDC2","GO:0003824(catalytic activity);GO:0016829(lyase activity);GO:0006629(lipid metabolic process);GO:0008152(metabolic process);GO:0006631(fatty acid metabolic process);GO:0005739(mitochondrion);GO:0006635(fatty acid beta-oxidation);GO:0004300(enoyl-CoA hydratase activity)","NA","NA","NA","enoyl-CoA hydratase domain containing 2 [Source:HGNC Symbol;Acc:HGNC:23408]",{"v":0.291376,"d":"0.29"},0,"inf","inf",1,1,"up","no"]
[147872,0,"chr4","-",68315855,68318721,"ENST00000507529",3,689,"MSTRG.11649","YTHDC1","GO:0003723(RNA binding);GO:0006397(mRNA processing);GO:0008380(RNA splicing);GO:0005634(nucleus);GO:0016607(nuclear speck);GO:0005654(nucleoplasm);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0006376(mRNA splice site selection);GO:0048024(regulation of mRNA splicing, via spliceosome);GO:1990247(N6-methyladenosine-containing RNA binding);GO:0000398(mRNA splicing, via spliceosome);GO:0016604(nuclear body)","NA","NA","NA","YTH domain containing 1 [Source:HGNC Symbol;Acc:HGNC:30626]",{"v":1.113821,"d":"1.11"},{"v":0.931281,"d":"0.93"},{"v":1.1960095824998,"d":"1.20"},{"v":0.258228948540671,"d":"0.26"},1,1,"up","no"]
[114041,0,"chr2","-",121407519,121427470,"ENST00000463621",4,536,"MSTRG.9079","CLASP1","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005794(Golgi apparatus);GO:0051301(cell division);GO:0005694(chromosome);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0007049(cell cycle);GO:0005874(microtubule);GO:0005925(focal adhesion);GO:0008017(microtubule binding);GO:0005813(centrosome);GO:0005815(microtubule organizing center);GO:0005819(spindle);GO:0000775(chromosome, centromeric region);GO:0000776(kinetochore);GO:0000777(condensed chromosome kinetochore);GO:0043515(kinetochore binding);GO:0070507(regulation of microtubule cytoskeleton organization);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0000086(G2/M transition of mitotic cell cycle);GO:0010389(regulation of G2/M transition of mitotic cell cycle);GO:0097711(ciliary basal body docking);GO:0051010(microtubule plus-end binding);GO:0005828(kinetochore microtubule);GO:0005881(cytoplasmic microtubule);GO:0010717(regulation of epithelial to mesenchymal transition);GO:0005876(spindle microtubule);GO:0007052(mitotic spindle organization);GO:0007062(sister chromatid cohesion);GO:0090307(mitotic spindle assembly);GO:0045921(positive regulation of exocytosis);GO:0000226(microtubule cytoskeleton organization);GO:0002162(dystroglycan binding);GO:0010458(exit from mitosis);GO:0007030(Golgi organization);GO:0010634(positive regulation of epithelial cell migration);GO:0051893(regulation of focal adhesion assembly);GO:0001578(microtubule bundle formation);GO:0090162(establishment of epithelial cell polarity);GO:0005938(cell cortex);GO:0006903(vesicle targeting);GO:0007020(microtubule nucleation);GO:0007026(negative regulation of microtubule depolymerization);GO:0007163(establishment or maintenance of cell polarity);GO:0010470(regulation of gastrulation);GO:0031023(microtubule organizing center organization);GO:0034453(microtubule anchoring);GO:0051497(negative regulation of stress fiber assembly);GO:0090091(positive regulation of extracellular matrix disassembly);GO:1903690(negative regulation of wound healing, spreading of epidermal cells);GO:1904261(positive regulation of basement membrane assembly involved in embryonic body morphogenesis);GO:0045180(basal cortex);GO:0031116(positive regulation of microtubule polymerization);GO:0030953(astral microtubule organization);GO:0051294(establishment of spindle orientation);GO:0035371(microtubule plus-end);GO:0031111(negative regulation of microtubule polymerization or depolymerization);GO:0040001(establishment of mitotic spindle localization);GO:0030981(cortical microtubule cytoskeleton);GO:0031592(centrosomal corona)","NA","NA","NA","cytoplasmic linker associated protein 1 [Source:HGNC Symbol;Acc:HGNC:17088]",{"v":6.679E-3,"d":"0.01"},0,"inf","inf",1,1,"up","no"]
[40670,0,"chr12","-",46207583,46268806,"ENST00000551506",5,586,"MSTRG.3311","SLC38A1","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0015293(symporter activity);GO:0006811(ion transport);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0006814(sodium ion transport);GO:0005887(integral component of plasma membrane);GO:0070062(extracellular exosome);GO:1902475(L-alpha-amino acid transmembrane transport);GO:0015171(amino acid transmembrane transporter activity);GO:0003333(amino acid transmembrane transport);GO:0006865(amino acid transport);GO:0015175(neutral amino acid transmembrane transporter activity);GO:0015804(neutral amino acid transport);GO:0015807(L-amino acid transport);GO:0001504(neurotransmitter uptake);GO:0005283(sodium:amino acid symporter activity);GO:0015179(L-amino acid transmembrane transporter activity);GO:0015186(L-glutamine transmembrane transporter activity);GO:0006868(glutamine transport);GO:0007565(female pregnancy);GO:0030424(axon)","04724(Glutamatergic synapse);04727(GABAergic synapse)","NA","NA","solute carrier family 38 member 1 [Source:HGNC Symbol;Acc:HGNC:13447]",0,0,1,0,1,1,"no","no"]
[100468,0,"chr19","+",36141190,36150349,"ENST00000590211",4,403,"MSTRG.8090","CAPNS1","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0046872(metal ion binding);GO:0005509(calcium ion binding);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0006508(proteolysis);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0022617(extracellular matrix disassembly);GO:0004198(calcium-dependent cysteine-type endopeptidase activity);GO:0016241(regulation of macroautophagy);GO:0070268(cornification);GO:0008284(positive regulation of cell proliferation);GO:0004175(endopeptidase activity)","NA","NA","NA","calpain small subunit 1 [Source:HGNC Symbol;Acc:HGNC:1481]",{"v":0.697789,"d":"0.70"},{"v":0.439857,"d":"0.44"},{"v":1.5863996708021,"d":"1.59"},{"v":0.66575628330205,"d":"0.67"},1,1,"up","no"]
[121186,0,"chr2","-",241500047,241501698,"ENST00000496159",3,463,"MSTRG.9527","STK25","GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0000165(MAPK cascade);GO:0016310(phosphorylation);GO:0005794(Golgi apparatus);GO:0042803(protein homodimerization activity);GO:0005515(protein binding);GO:0007163(establishment or maintenance of cell polarity);GO:0050772(positive regulation of axonogenesis);GO:0051645(Golgi localization);GO:0000139(Golgi membrane);GO:0000185(activation of MAPKKK activity);GO:0070062(extracellular exosome);GO:0048812(neuron projection morphogenesis);GO:0006979(response to oxidative stress);GO:0007165(signal transduction);GO:0042981(regulation of apoptotic process);GO:0046777(protein autophosphorylation);GO:0008349(MAP kinase kinase kinase kinase activity);GO:0007346(regulation of mitotic cell cycle);GO:0032874(positive regulation of stress-activated MAPK cascade);GO:0036481(intrinsic apoptotic signaling pathway in response to hydrogen peroxide);GO:0042542(response to hydrogen peroxide);GO:0051683(establishment of Golgi localization);GO:0090168(Golgi reassembly)","NA","NA","NA","serine/threonine kinase 25 [Source:HGNC Symbol;Acc:HGNC:11404]",{"v":0.471026,"d":"0.47"},0,"inf","inf",1,1,"up","no"]
[171413,0,"chr7","+",2647956,2649987,"ENST00000477439",3,731,"MSTRG.13457","TTYH3","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0006811(ion transport);GO:0005886(plasma membrane);GO:0005254(chloride channel activity);GO:0006821(chloride transport);GO:0034707(chloride channel complex);GO:1902476(chloride transmembrane transport);GO:0070062(extracellular exosome);GO:0005229(intracellular calcium activated chloride channel activity);GO:0034220(ion transmembrane transport)","NA","NA","NA","tweety family member 3 [Source:HGNC Symbol;Acc:HGNC:22222]",{"v":0.136359,"d":"0.14"},{"v":0.241789,"d":"0.24"},{"v":0.563958658168899,"d":"0.56"},{"v":-0.826338687300156,"d":"-0.83"},1,1,"down","no"]
[140026,0,"chr3","-",126006373,126084304,"ENST00000315891",12,1797,"ENSG00000114544","SLC41A3","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0098655(cation transmembrane transport);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0006812(cation transport);GO:0055085(transmembrane transport);GO:0008324(cation transmembrane transporter activity)","NA","NA","NA","solute carrier family 41 member 3 [Source:HGNC Symbol;Acc:HGNC:31046]",0,{"v":1.398634,"d":"1.40"},"-inf","-inf",1,1,"down","no"]
[22014,0,"chr10","-",87286898,87308584,"ENST00000420424",2,2226,"ENSG00000223482","NUTM2A-AS1","NA","NA","NA","NA","NUTM2A antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:45161]",{"v":0.072058,"d":"0.07"},{"v":0.614185,"d":"0.61"},{"v":0.117322956438207,"d":"0.12"},{"v":-3.09144276354008,"d":"-3.09"},1,1,"down","no"]
[111727,0,"chr2","-",85558584,85561493,"ENST00000481541",2,600,"MSTRG.8871","GGCX","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016829(lyase activity);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0008488(gamma-glutamyl carboxylase activity);GO:0017187(peptidyl-glutamic acid carboxylation);GO:0007596(blood coagulation);GO:0006464(cellular protein modification process)","00130(Ubiquinone and other terpenoid-quinone biosynthesis)","NA","NA","gamma-glutamyl carboxylase [Source:HGNC Symbol;Acc:HGNC:4247]",{"v":0.010162,"d":"0.01"},{"v":0.184067,"d":"0.18"},{"v":0.0552081578990259,"d":"0.06"},{"v":-4.17897472547293,"d":"-4.18"},1,1,"down","no"]
[128115,0,"chr21","+",46648318,46649888,"ENST00000491389",2,616,"MSTRG.10096","PRMT2","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0008168(methyltransferase activity);GO:0016740(transferase activity);GO:0032259(methylation);GO:0042803(protein homodimerization activity);GO:0005515(protein binding);GO:0006479(protein methylation);GO:0003713(transcription coactivator activity);GO:0045893(positive regulation of transcription, DNA-templated);GO:0005730(nucleolus);GO:0030331(estrogen receptor binding);GO:0042974(retinoic acid receptor binding);GO:0032088(negative regulation of NF-kappaB transcription factor activity);GO:0043065(positive regulation of apoptotic process);GO:0004871(signal transducer activity);GO:0007165(signal transduction);GO:0045892(negative regulation of transcription, DNA-templated);GO:0016274(protein-arginine N-methyltransferase activity);GO:0050681(androgen receptor binding);GO:0042054(histone methyltransferase activity);GO:0008469(histone-arginine N-methyltransferase activity);GO:0035242(protein-arginine omega-N asymmetric methyltransferase activity);GO:0019919(peptidyl-arginine methylation, to asymmetrical-dimethyl arginine);GO:0034969(histone arginine methylation);GO:0035246(peptidyl-arginine N-methylation);GO:0046966(thyroid hormone receptor binding);GO:2000134(negative regulation of G1/S transition of mitotic cell cycle);GO:0048588(developmental cell growth);GO:0042975(peroxisome proliferator activated receptor binding);GO:0060765(regulation of androgen receptor signaling pathway);GO:0035189(Rb-E2F complex);GO:0033142(progesterone receptor binding);GO:0016571(histone methylation)","NA","NA","NA","protein arginine methyltransferase 2 [Source:HGNC Symbol;Acc:HGNC:5186]",{"v":1.63E-4,"d":"0.00"},0,"inf","inf",1,1,"up","no"]
[91182,0,"chr18","+",22169443,22202528,"ENST00000269216",7,3770,"ENSG00000141448","GATA6","GO:0005634(nucleus);GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0006355(regulation of transcription, DNA-templated);GO:0045893(positive regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0031965(nuclear membrane);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0043565(sequence-specific DNA binding);GO:0003682(chromatin binding);GO:0005515(protein binding);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0005654(nucleoplasm);GO:0019901(protein kinase binding);GO:0044267(cellular protein metabolic process);GO:0008584(male gonad development);GO:0005667(transcription factor complex);GO:0000977(RNA polymerase II regulatory region sequence-specific DNA binding);GO:0001228(transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding);GO:0043066(negative regulation of apoptotic process);GO:0008134(transcription factor binding);GO:0044212(transcription regulatory region DNA binding);GO:0045892(negative regulation of transcription, DNA-templated);GO:0000981(RNA polymerase II transcription factor activity, sequence-specific DNA binding);GO:0045766(positive regulation of angiogenesis);GO:0110024(-);GO:0071456(cellular response to hypoxia);GO:0007596(blood coagulation);GO:0071158(positive regulation of cell cycle arrest);GO:0006366(transcription from RNA polymerase II promoter);GO:0003148(outflow tract septum morphogenesis);GO:0042493(response to drug);GO:0070848(response to growth factor);GO:0001085(RNA polymerase II transcription factor binding);GO:0032912(negative regulation of transforming growth factor beta2 production);GO:0060575(intestinal epithelial cell differentiation);GO:0051145(smooth muscle cell differentiation);GO:0030513(positive regulation of BMP signaling pathway);GO:0000979(RNA polymerase II core promoter sequence-specific DNA binding);GO:0001103(RNA polymerase II repressing transcription factor binding);GO:0003705(transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding);GO:0001701(in utero embryonic development);GO:0001889(liver development);GO:0003309(type B pancreatic cell differentiation);GO:0003310(pancreatic A cell differentiation);GO:0006644(phospholipid metabolic process);GO:0007493(endodermal cell fate determination);GO:0010468(regulation of gene expression);GO:0014898(cardiac muscle hypertrophy in response to stress);GO:0030855(epithelial cell differentiation);GO:0031016(pancreas development);GO:0032911(negative regulation of transforming growth factor beta1 production);GO:0035239(tube morphogenesis);GO:0035987(endodermal cell differentiation);GO:0043627(response to estrogen);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0048645(animal organ formation);GO:0048738(cardiac muscle tissue development);GO:0051891(positive regulation of cardioblast differentiation);GO:0055007(cardiac muscle cell differentiation);GO:0060045(positive regulation of cardiac muscle cell proliferation);GO:0060430(lung saccule development);GO:0060486(Clara cell differentiation);GO:0060510(Type II pneumocyte differentiation);GO:0060947(cardiac vascular smooth muscle cell differentiation);GO:0071371(cellular response to gonadotropin stimulus);GO:0071773(cellular response to BMP stimulus)","NA","NA","NA","GATA binding protein 6 [Source:HGNC Symbol;Acc:HGNC:4174]",0,0,1,0,1,1,"no","no"]
[99673,0,"chr19","-",32830515,32869736,"ENST00000590465",9,1998,"ENSG00000021488","SLC7A9","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0015171(amino acid transmembrane transporter activity);GO:0003333(amino acid transmembrane transport);GO:0050900(leukocyte migration);GO:0006865(amino acid transport);GO:0005887(integral component of plasma membrane);GO:0015297(antiporter activity);GO:0016324(apical plasma membrane);GO:0006461(protein complex assembly);GO:0031526(brush border membrane);GO:0042605(peptide antigen binding);GO:0015184(L-cystine transmembrane transporter activity);GO:0015811(L-cystine transport);GO:0015175(neutral amino acid transmembrane transporter activity);GO:0015804(neutral amino acid transport)","04974(Protein digestion and absorption)","NA","NA","solute carrier family 7 member 9 [Source:HGNC Symbol;Acc:HGNC:11067]",0,{"v":0.034862,"d":"0.03"},"-inf","-inf",1,1,"down","no"]
[96070,0,"chr19","+",9185594,9188817,"ENST00000344248",1,3224,"ENSG00000188000","OR7D2","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0004930(G-protein coupled receptor activity);GO:0007186(G-protein coupled receptor signaling pathway);GO:0005886(plasma membrane);GO:0004871(signal transducer activity);GO:0007165(signal transduction);GO:0004984(olfactory receptor activity);GO:0007608(sensory perception of smell);GO:0050896(response to stimulus);GO:0050911(detection of chemical stimulus involved in sensory perception of smell);GO:0006355(regulation of transcription, DNA-templated)","04740(Olfactory transduction)","K04257","NA","olfactory receptor family 7 subfamily D member 2 [Source:HGNC Symbol;Acc:HGNC:8378]",{"v":0.066201,"d":"0.07"},{"v":0.111324,"d":"0.11"},{"v":0.594669613021451,"d":"0.59"},{"v":-0.749839737456932,"d":"-0.75"},1,1,"down","no"]
[77690,0,"chr17","-",2324691,2330966,"ENST00000575049",4,387,"ENSG00000167721","TSR1","GO:0005634(nucleus);GO:0003723(RNA binding);GO:0042254(ribosome biogenesis);GO:0005730(nucleolus);GO:0030688(preribosome, small subunit precursor);GO:0000462(maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA));GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0003924(GTPase activity);GO:0006364(rRNA processing);GO:0034511(U3 snoRNA binding);GO:0042255(ribosome assembly);GO:0005525(GTP binding);GO:0000479(endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA))","NA","NA","NA","TSR1, ribosome maturation factor [Source:HGNC Symbol;Acc:HGNC:25542]",{"v":0.254515,"d":"0.25"},0,"inf","inf",1,1,"up","no"]
[160424,0,"chr5","+",154959051,154966971,"ENST00000518364",3,481,"ENSG00000082515","MRPL22","GO:0003723(RNA binding);GO:0030529(intracellular ribonucleoprotein complex);GO:0003735(structural constituent of ribosome);GO:0006412(translation);GO:0005840(ribosome);GO:0005739(mitochondrion);GO:0015934(large ribosomal subunit);GO:0005743(mitochondrial inner membrane);GO:0070125(mitochondrial translational elongation);GO:0070126(mitochondrial translational termination);GO:0005762(mitochondrial large ribosomal subunit)","03010(Ribosome)","NA","NA","mitochondrial ribosomal protein L22 [Source:HGNC Symbol;Acc:HGNC:14480]",0,{"v":0.225146,"d":"0.23"},"-inf","-inf",1,1,"down","no"]
[158450,0,"chr5","+",134524312,134559967,"ENST00000512386",5,567,"MSTRG.12313","JADE2","GO:0005654(nucleoplasm);GO:0046872(metal ion binding);GO:0061630(ubiquitin protein ligase activity);GO:0000209(protein polyubiquitination);GO:0050767(regulation of neurogenesis);GO:0050769(positive regulation of neurogenesis);GO:0051865(protein autoubiquitination);GO:0060395(SMAD protein signal transduction);GO:1990138(neuron projection extension);GO:0016740(transferase activity);GO:0016567(protein ubiquitination);GO:0005515(protein binding);GO:0070062(extracellular exosome);GO:0043981(histone H4-K5 acetylation);GO:0043982(histone H4-K8 acetylation);GO:0000123(histone acetyltransferase complex);GO:0043966(histone H3 acetylation);GO:0043983(histone H4-K12 acetylation)","NA","NA","NA","jade family PHD finger 2 [Source:HGNC Symbol;Acc:HGNC:22984]",{"v":0.628148,"d":"0.63"},{"v":0.542518,"d":"0.54"},{"v":1.15783808094847,"d":"1.16"},{"v":0.211433512268502,"d":"0.21"},1,1,"up","no"]
[173605,0,"chr7","-",44114687,44123508,"ENST00000406581",12,2158,"MSTRG.13629","POLD2","GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0006281(DNA repair);GO:0006974(cellular response to DNA damage stimulus);GO:0006260(DNA replication);GO:0003887(DNA-directed DNA polymerase activity);GO:0043625(delta DNA polymerase complex);GO:0019985(translesion synthesis);GO:0006283(transcription-coupled nucleotide-excision repair);GO:0042769(DNA damage response, detection of DNA damage);GO:0006296(nucleotide-excision repair, DNA incision, 5'-to lesion);GO:0033683(nucleotide-excision repair, DNA incision);GO:0032201(telomere maintenance via semi-conservative replication);GO:0006297(nucleotide-excision repair, DNA gap filling);GO:0000723(telomere maintenance);GO:0006266(DNA ligation);GO:0006298(mismatch repair);GO:0006271(DNA strand elongation involved in DNA replication);GO:0071897(DNA biosynthetic process);GO:0006261(DNA-dependent DNA replication)","00230(Purine metabolism);00240(Pyrimidine metabolism);03030(DNA replication);03410(Base excision repair);03420(Nucleotide excision repair);03430(Mismatch repair);03440(Homologous recombination);05166(HTLV-I infection)","K02328","NA","DNA polymerase delta 2, accessory subunit [Source:HGNC Symbol;Acc:HGNC:9176]",{"v":0.000715,"d":"0.00"},{"v":0.026857,"d":"0.03"},{"v":0.0266224820344789,"d":"0.03"},{"v":-5.23121110868617,"d":"-5.23"},1,1,"down","no"]
[172563,0,"chr7","-",26844029,26865113,"ENST00000481204",4,513,"MSTRG.13531","SKAP2","GO:0005737(cytoplasm);GO:0009967(positive regulation of signal transduction);GO:0005515(protein binding);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0042113(B cell activation);GO:0007165(signal transduction);GO:0006461(protein complex assembly);GO:0005070(SH3/SH2 adaptor activity);GO:0002757(immune response-activating signal transduction);GO:0008285(negative regulation of cell proliferation)","NA","NA","NA","src kinase associated phosphoprotein 2 [Source:HGNC Symbol;Acc:HGNC:15687]",{"v":0.18311,"d":"0.18"},0,"inf","inf",1,1,"up","no"]
[39170,0,"chr12","+",14365684,14447030,"ENST00000538511",5,558,"MSTRG.3227","ATF7IP","GO:0005634(nucleus);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0005515(protein binding);GO:0016604(nuclear body);GO:0045893(positive regulation of transcription, DNA-templated);GO:0016032(viral process);GO:0045892(negative regulation of transcription, DNA-templated);GO:0006306(DNA methylation);GO:0045898(regulation of RNA polymerase II transcriptional preinitiation complex assembly);GO:0003714(transcription corepressor activity);GO:0016887(ATPase activity);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0005667(transcription factor complex)","NA","NA","NA","activating transcription factor 7 interacting protein [Source:HGNC Symbol;Acc:HGNC:20092]",0,0,1,0,1,1,"no","no"]
[172361,0,"chr7","+",23298739,23300924,"ENST00000479974",2,497,"ENSG00000156928","MALSU1","GO:0005829(cytosol);GO:0005739(mitochondrion);GO:0005515(protein binding);GO:0005759(mitochondrial matrix);GO:0042273(ribosomal large subunit biogenesis);GO:0043023(ribosomal large subunit binding);GO:0070130(negative regulation of mitochondrial translation);GO:0090071(negative regulation of ribosome biogenesis)","NA","NA","NA","mitochondrial assembly of ribosomal large subunit 1 [Source:HGNC Symbol;Acc:HGNC:21721]",0,0,1,0,1,1,"no","no"]
[52920,"j","chr14","+",22600119,22612150,"MSTRG.4171.8",7,2283,"MSTRG.4171","ABHD4","NA","NA","NA","NA","NA",{"v":10.865734,"d":"10.87"},0,"inf","inf",1,1,"up","no"]
[57036,0,"chr14","+",75970924,75971587,"ENST00000553732",2,580,"MSTRG.4571","TGFB3-AS1","NA","NA","NA","NA","TGFB3 antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:53144]",{"v":0.047404,"d":"0.05"},{"v":0.222523,"d":"0.22"},{"v":0.213029664349303,"d":"0.21"},{"v":-2.23087375537624,"d":"-2.23"},1,1,"down","no"]
[95278,0,"chr19","+",5681061,5688493,"ENST00000581521",10,1884,"MSTRG.7711","HSD11B1L","GO:0043231(intracellular membrane-bounded organelle);GO:0005654(nucleoplasm);GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0005576(extracellular region)","NA","NA","NA","hydroxysteroid 11-beta dehydrogenase 1 like [Source:HGNC Symbol;Acc:HGNC:30419]",0,0,1,0,1,1,"no","no"]
[5737,0,"chr1","+",46671828,46673594,"ENST00000334122",2,866,"ENSG00000186118","TEX38","GO:0016020(membrane);GO:0016021(integral component of membrane)","NA","NA","NA","testis expressed 38 [Source:HGNC Symbol;Acc:HGNC:29589]",{"v":0.166196,"d":"0.17"},{"v":0.049395,"d":"0.05"},{"v":3.36463204777812,"d":"3.36"},{"v":1.75044874202106,"d":"1.75"},1,1,"up","no"]
[45465,0,"chr12","+",96247131,96267357,"ENST00000549985",4,684,"MSTRG.3621","ELK3","GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0006355(regulation of transcription, DNA-templated);GO:0006366(transcription from RNA polymerase II promoter);GO:0006351(transcription, DNA-templated);GO:0005739(mitochondrion);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0043565(sequence-specific DNA binding);GO:0005515(protein binding);GO:0001525(angiogenesis);GO:0042060(wound healing);GO:0045892(negative regulation of transcription, DNA-templated);GO:0045893(positive regulation of transcription, DNA-templated);GO:0005737(cytoplasm);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0030154(cell differentiation);GO:0007165(signal transduction);GO:0001077(transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0003714(transcription corepressor activity);GO:0032422(purine-rich negative regulatory element binding)","NA","NA","NA","ELK3, ETS transcription factor [Source:HGNC Symbol;Acc:HGNC:3325]",0,0,1,0,1,1,"no","no"]
[191349,0,"chr9","-",83739504,83749155,"ENST00000376362",4,1237,"ENSG00000165113","GKAP1","GO:0007165(signal transduction);GO:0005794(Golgi apparatus);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0005515(protein binding);GO:0042802(identical protein binding)","NA","NA","NA","G kinase anchoring protein 1 [Source:HGNC Symbol;Acc:HGNC:17496]",{"v":0.005158,"d":"0.01"},0,"inf","inf",1,1,"up","no"]
[143487,0,"chr3","+",184314569,184325299,"ENST00000426123",18,2907,"MSTRG.11394","EIF4G1","GO:0003723(RNA binding);GO:0016020(membrane);GO:0003743(translation initiation factor activity);GO:0006412(translation);GO:0006413(translational initiation);GO:0006446(regulation of translational initiation);GO:0005515(protein binding);GO:0008190(eukaryotic initiation factor 4E binding);GO:0005829(cytosol);GO:0045296(cadherin binding);GO:0043488(regulation of mRNA stability);GO:0000289(nuclear-transcribed mRNA poly(A) tail shortening);GO:0006417(regulation of translation);GO:0016032(viral process);GO:0010507(negative regulation of autophagy);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0008135(translation factor activity, RNA binding);GO:0007005(mitochondrion organization);GO:0005524(ATP binding);GO:0000184(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay);GO:0016281(eukaryotic translation initiation factor 4F complex);GO:1901215(negative regulation of neuron death);GO:0033138(positive regulation of peptidyl-serine phosphorylation);GO:0008284(positive regulation of cell proliferation);GO:1905606(regulation of presynapse assembly);GO:0010801(negative regulation of peptidyl-threonine phosphorylation);GO:0030307(positive regulation of cell growth);GO:0034645(cellular macromolecule biosynthetic process);GO:0022627(cytosolic small ribosomal subunit);GO:0003729(mRNA binding);GO:0031369(translation initiation factor binding);GO:0032947(protein complex scaffold);GO:0002191(cap-dependent translational initiation);GO:0032270(positive regulation of cellular protein metabolic process);GO:0032502(developmental process);GO:0060964(regulation of gene silencing by miRNA);GO:0080135(regulation of cellular response to stress);GO:1900087(positive regulation of G1/S transition of mitotic cell cycle);GO:1905537(positive regulation of eukaryotic translation initiation factor 4F complex assembly);GO:1905612(positive regulation of mRNA cap binding);GO:1905618(positive regulation of miRNA mediated inhibition of translation);GO:1905696(regulation of polysome binding);GO:2000507(positive regulation of energy homeostasis);GO:0005844(polysome);GO:0001662(behavioral fear response);GO:0045666(positive regulation of neuron differentiation)","03013(RNA transport);05416(Viral myocarditis)","NA","NA","eukaryotic translation initiation factor 4 gamma 1 [Source:HGNC Symbol;Acc:HGNC:3296]",{"v":0.062081,"d":"0.06"},{"v":0.029024,"d":"0.03"},{"v":2.138953969129,"d":"2.14"},{"v":1.09690543564747,"d":"1.10"},1,1,"up","no"]
[195607,0,"chrX","+",9534943,9684070,"ENST00000452824",5,387,"MSTRG.15163","TBL1X","GO:0005634(nucleus);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0005515(protein binding);GO:0006508(proteolysis);GO:0045893(positive regulation of transcription, DNA-templated);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0003714(transcription corepressor activity);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0005654(nucleoplasm);GO:0007605(sensory perception of sound);GO:0008022(protein C-terminus binding);GO:0000118(histone deacetylase complex);GO:0005876(spindle microtubule);GO:0019904(protein domain specific binding);GO:0008134(transcription factor binding);GO:0042393(histone binding);GO:0044212(transcription regulatory region DNA binding);GO:0043161(proteasome-mediated ubiquitin-dependent protein catabolic process);GO:0008013(beta-catenin binding);GO:0060070(canonical Wnt signaling pathway);GO:0019216(regulation of lipid metabolic process);GO:0017053(transcriptional repressor complex);GO:0016575(histone deacetylation)","04310(Wnt signaling pathway)","NA","NA","transducin beta like 1X-linked [Source:HGNC Symbol;Acc:HGNC:11585]",0,0,1,0,1,1,"no","no"]
[108310,0,"chr2","+",27628247,27650363,"ENST00000515877",14,1646,"MSTRG.8601","GPN1","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0000166(nucleotide binding);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0016787(hydrolase activity);GO:0005739(mitochondrion);GO:0003924(GTPase activity);GO:0005525(GTP binding);GO:0005515(protein binding);GO:0044376(RNA polymerase II complex import to nucleus);GO:1990022(RNA polymerase III complex localization to nucleus)","NA","NA","NA","GPN-loop GTPase 1 [Source:HGNC Symbol;Acc:HGNC:17030]",{"v":0.064067,"d":"0.06"},{"v":0.103534,"d":"0.10"},{"v":0.618801553112987,"d":"0.62"},{"v":-0.692451277115294,"d":"-0.69"},1,1,"down","no"]
[29756,0,"chr11","+",60729304,60744212,"ENST00000529108",6,1433,"ENSG00000214782","AP004243.1","GO:0016020(membrane);GO:0016021(integral component of membrane)","NA","NA","NA","Membrane-spanning 4-domains subfamily A member 18  [Source:UniProtKB/Swiss-Prot;Acc:Q3C1V0]",{"v":0.032755,"d":"0.03"},{"v":0.063358,"d":"0.06"},{"v":0.516982859307428,"d":"0.52"},{"v":-0.951811646459554,"d":"-0.95"},1,1,"down","no"]
[149161,0,"chr4","-",87473348,87529503,"ENST00000418378",12,2994,"ENSG00000152583","SPARCL1","GO:0005615(extracellular space);GO:0046872(metal ion binding);GO:0005509(calcium ion binding);GO:0007165(signal transduction);GO:0005576(extracellular region);GO:0005578(proteinaceous extracellular matrix);GO:0070062(extracellular exosome);GO:0044267(cellular protein metabolic process);GO:0043687(post-translational protein modification);GO:0005788(endoplasmic reticulum lumen);GO:0050840(extracellular matrix binding);GO:0005518(collagen binding);GO:0048856(anatomical structure development)","NA","NA","NA","SPARC like 1 [Source:HGNC Symbol;Acc:HGNC:11220]",{"v":0.055225,"d":"0.06"},{"v":0.050393,"d":"0.05"},{"v":1.09588633341932,"d":"1.10"},{"v":0.132098168082764,"d":"0.13"},1,1,"up","no"]
[92338,0,"chr18","-",49378623,49460627,"ENST00000579058",7,869,"ENSG00000141627","DYM","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005794(Golgi apparatus);GO:0005515(protein binding);GO:0060348(bone development);GO:0019899(enzyme binding);GO:0007030(Golgi organization)","NA","NA","NA","dymeclin [Source:HGNC Symbol;Acc:HGNC:21317]",0,{"v":0.076542,"d":"0.08"},"-inf","-inf",1,1,"down","no"]
[95895,0,"chr19","+",8225027,8256675,"ENST00000558877",8,758,"ENSG00000090661","CERS4","GO:0016021(integral component of membrane);GO:0005783(endoplasmic reticulum);GO:0005634(nucleus);GO:0016020(membrane);GO:0003677(DNA binding);GO:0006629(lipid metabolic process);GO:0005789(endoplasmic reticulum membrane);GO:0031965(nuclear membrane);GO:0030148(sphingolipid biosynthetic process);GO:0046513(ceramide biosynthetic process);GO:0050291(sphingosine N-acyltransferase activity)","00600(Sphingolipid metabolism);04071(Sphingolipid signaling pathway)","NA","NA","ceramide synthase 4 [Source:HGNC Symbol;Acc:HGNC:23747]",0,{"v":0.121165,"d":"0.12"},"-inf","-inf",1,1,"down","no"]
[101893,0,"chr19","+",41579521,41586844,"ENST00000632983",6,710,"MSTRG.8169","CEACAM21","GO:0016020(membrane);GO:0016021(integral component of membrane)","NA","NA","NA","carcinoembryonic antigen related cell adhesion molecule 21 [Source:HGNC Symbol;Acc:HGNC:28834]",{"v":0.492995,"d":"0.49"},{"v":0.281064,"d":"0.28"},{"v":1.75403111035209,"d":"1.75"},{"v":0.810674336353141,"d":"0.81"},1,1,"up","no"]
[5715,0,"chr1","-",46584547,46604246,"ENST00000525888",4,588,"MSTRG.540","MKNK1","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0005654(nucleoplasm);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0005515(protein binding);GO:0005829(cytosol);GO:0006417(regulation of translation);GO:0005516(calmodulin binding);GO:0035556(intracellular signal transduction);GO:0018105(peptidyl-serine phosphorylation);GO:0004683(calmodulin-dependent protein kinase activity);GO:0009931(calcium-dependent protein serine/threonine kinase activity);GO:0046777(protein autophosphorylation)","04010(MAPK signaling pathway);04066(HIF-1 signaling pathway);04910(Insulin signaling pathway)","NA","NA","MAP kinase interacting serine/threonine kinase 1 [Source:HGNC Symbol;Acc:HGNC:7110]",0,{"v":0.004323,"d":"0.00"},"-inf","-inf",1,1,"down","no"]
[36190,0,"chr11","+",120337078,120489936,"ENST00000397843",41,9660,"ENSG00000196914","ARHGEF12","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0035556(intracellular signal transduction);GO:0005089(Rho guanyl-nucleotide exchange factor activity);GO:0035023(regulation of Rho protein signal transduction);GO:0043547(positive regulation of GTPase activity);GO:0005515(protein binding);GO:0005096(GTPase activator activity);GO:0005085(guanyl-nucleotide exchange factor activity);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0051056(regulation of small GTPase mediated signal transduction);GO:0043065(positive regulation of apoptotic process);GO:0001664(G-protein coupled receptor binding);GO:0007186(G-protein coupled receptor signaling pathway)","04810(Regulation of actin cytoskeleton);04611(Platelet activation);04270(Vascular smooth muscle contraction);04360(Axon guidance);05200(Pathways in cancer);05205(Proteoglycans in cancer);05152(Tuberculosis)","K07532","NA","Rho guanine nucleotide exchange factor 12 [Source:HGNC Symbol;Acc:HGNC:14193]",{"v":0.052509,"d":"0.05"},{"v":1.32131,"d":"1.32"},{"v":0.0397401064095481,"d":"0.04"},{"v":-4.65326045416948,"d":"-4.65"},1,1,"down","no"]
[173149,"j","chr7","+",35801081,35906057,"MSTRG.13571.7",13,3196,"MSTRG.13571","SEPT7","NA","NA","NA","NA","NA",{"v":5.793076,"d":"5.79"},0,"inf","inf",1,1,"up","no"]
[188719,0,"chr9","+",2017087,2039689,"ENST00000457226",4,736,"MSTRG.14677","SMARCA2","GO:0016514(SWI/SNF complex);GO:0016887(ATPase activity);GO:0006338(chromatin remodeling);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0005634(nucleus);GO:0043231(intracellular membrane-bounded organelle);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0005654(nucleoplasm);GO:0006355(regulation of transcription, DNA-templated);GO:0016787(hydrolase activity);GO:0006351(transcription, DNA-templated);GO:0004386(helicase activity);GO:0003677(DNA binding);GO:0045111(intermediate filament cytoskeleton);GO:0005515(protein binding);GO:0007399(nervous system development);GO:0045893(positive regulation of transcription, DNA-templated);GO:0042393(histone binding);GO:0016817(hydrolase activity, acting on acid anhydrides);GO:0008285(negative regulation of cell proliferation);GO:0003713(transcription coactivator activity);GO:0044212(transcription regulatory region DNA binding);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0000790(nuclear chromatin);GO:0045892(negative regulation of transcription, DNA-templated);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0071564(npBAF complex);GO:0071565(nBAF complex);GO:0001105(RNA polymerase II transcription coactivator activity);GO:0030308(negative regulation of cell growth);GO:0008094(DNA-dependent ATPase activity);GO:0003682(chromatin binding);GO:0007286(spermatid development)","05225(Hepatocellular carcinoma)","NA","NA","SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 [Source:HGNC Symbol;Acc:HGNC:11098]",{"v":1.931019,"d":"1.93"},{"v":0.51421,"d":"0.51"},{"v":3.75531203204916,"d":"3.76"},{"v":1.90893278746978,"d":"1.91"},1,1,"up","no"]
[108969,0,"chr2","-",38810432,38811654,"ENST00000439895",1,1223,"ENSG00000223922","ASS1P2","NA","NA","NA","NA","argininosuccinate synthetase 1 pseudogene 2 [Source:HGNC Symbol;Acc:HGNC:765]",{"v":0.123847,"d":"0.12"},{"v":0.036932,"d":"0.04"},{"v":3.35337918336402,"d":"3.35"},{"v":1.74561562510279,"d":"1.75"},1,1,"up","no"]
[21414,0,"chr10","+",74976521,75026164,"ENST00000490365",8,6532,"ENSG00000156650","KAT6B","GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0016740(transferase activity);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0016569(covalent chromatin modification);GO:0003677(DNA binding);GO:0016746(transferase activity, transferring acyl groups);GO:0006334(nucleosome assembly);GO:0000786(nucleosome);GO:0016747(transferase activity, transferring acyl groups other than amino-acyl groups);GO:0004402(histone acetyltransferase activity);GO:0045893(positive regulation of transcription, DNA-templated);GO:0005515(protein binding);GO:0005654(nucleoplasm);GO:0008134(transcription factor binding);GO:0045892(negative regulation of transcription, DNA-templated);GO:0043966(histone H3 acetylation);GO:0070776(MOZ/MORF histone acetyltransferase complex);GO:0016407(acetyltransferase activity);GO:0016573(histone acetylation);GO:0032403(protein complex binding);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:1990830(cellular response to leukemia inhibitory factor)","NA","NA","NA","lysine acetyltransferase 6B [Source:HGNC Symbol;Acc:HGNC:17582]",{"v":0.023608,"d":"0.02"},{"v":0.053232,"d":"0.05"},{"v":0.443492636008416,"d":"0.44"},{"v":-1.17301794545086,"d":"-1.17"},1,1,"down","no"]
[357,0,"chr1","-",1314313,1315697,"ENST00000533916",4,405,"MSTRG.63","INTS11","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0016787(hydrolase activity);GO:0072562(blood microparticle);GO:0005515(protein binding);GO:0042795(snRNA transcription from RNA polymerase II promoter);GO:0016180(snRNA processing);GO:0032039(integrator complex)","NA","NA","NA","integrator complex subunit 11 [Source:HGNC Symbol;Acc:HGNC:26052]",0,0,1,0,1,1,"no","no"]
[143263,0,"chr3","+",183447608,183456013,"ENST00000471496",4,1490,"ENSG00000240024","LINC00888","NA","NA","NA","NA","long intergenic non-protein coding RNA 888 [Source:HGNC Symbol;Acc:HGNC:48575]",0,{"v":0.04504,"d":"0.05"},"-inf","-inf",1,1,"down","no"]
[78886,0,"chr17","+",7572826,7576690,"ENST00000582169",5,552,"MSTRG.6423","EIF4A1","GO:0003676(nucleic acid binding);GO:0005524(ATP binding);GO:0000166(nucleotide binding);GO:0016787(hydrolase activity);GO:0004386(helicase activity);GO:0003723(RNA binding);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0003743(translation initiation factor activity);GO:0006412(translation);GO:0006413(translational initiation);GO:0005515(protein binding);GO:0003729(mRNA binding);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0004004(ATP-dependent RNA helicase activity);GO:0010501(RNA secondary structure unwinding);GO:0000289(nuclear-transcribed mRNA poly(A) tail shortening);GO:0016032(viral process);GO:0031012(extracellular matrix);GO:0010468(regulation of gene expression);GO:0003725(double-stranded RNA binding);GO:0016281(eukaryotic translation initiation factor 4F complex);GO:0008135(translation factor activity, RNA binding);GO:0000339(RNA cap binding)","03013(RNA transport)","NA","NA","eukaryotic translation initiation factor 4A1 [Source:HGNC Symbol;Acc:HGNC:3282]",0,{"v":0.074358,"d":"0.07"},"-inf","-inf",1,1,"down","no"]
[85905,0,"chr17","-",56890521,56891526,"ENST00000573108",2,952,"MSTRG.7040","TRIM25","GO:0003723(RNA binding);GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0016740(transferase activity);GO:0016567(protein ubiquitination);GO:0016874(ligase activity);GO:0005515(protein binding);GO:0016604(nuclear body);GO:0002376(immune system process);GO:0045087(innate immune response);GO:0051607(defense response to virus);GO:1904264(ubiquitin protein ligase activity involved in ERAD pathway);GO:0045296(cadherin binding);GO:0016579(protein deubiquitination);GO:0016032(viral process);GO:0042787(protein ubiquitination involved in ubiquitin-dependent protein catabolic process);GO:0043123(positive regulation of I-kappaB kinase/NF-kappaB signaling);GO:0051092(positive regulation of NF-kappaB transcription factor activity);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0051091(positive regulation of sequence-specific DNA binding transcription factor activity);GO:0060333(interferon-gamma-mediated signaling pathway);GO:0043627(response to estrogen);GO:0019985(translesion synthesis);GO:0032480(negative regulation of type I interferon production);GO:0004842(ubiquitin-protein transferase activity);GO:0006513(protein monoubiquitination);GO:0030433(ubiquitin-dependent ERAD pathway);GO:0036503(ERAD pathway);GO:0033280(response to vitamin D);GO:0046596(regulation of viral entry into host cell);GO:0046597(negative regulation of viral entry into host cell);GO:1902186(regulation of viral release from host cell);GO:1902187(negative regulation of viral release from host cell);GO:1990830(cellular response to leukemia inhibitory factor)","04064(NF-kappa B signaling pathway);04622(RIG-I-like receptor signaling pathway);05164(Influenza A)","NA","NA","tripartite motif containing 25 [Source:HGNC Symbol;Acc:HGNC:12932]",0,0,1,0,1,1,"no","no"]
[107535,0,"chr2","+",16970034,16974497,"ENST00000421181",3,201,"ENSG00000237670","LINC01866","NA","NA","NA","NA","long intergenic non-protein coding RNA 1866 [Source:HGNC Symbol;Acc:HGNC:52685]",0,{"v":0.005296,"d":"0.01"},"-inf","-inf",1,1,"down","no"]
[42052,0,"chr12","-",53160291,53170890,"ENST00000485004",5,751,"MSTRG.3393","CSAD","GO:0003824(catalytic activity);GO:0016829(lyase activity);GO:0016831(carboxy-lyase activity);GO:0030170(pyridoxal phosphate binding);GO:0019752(carboxylic acid metabolic process);GO:0042412(taurine biosynthetic process);GO:0004782(sulfinoalanine decarboxylase activity)","00430(Taurine and hypotaurine metabolism)","NA","NA","cysteine sulfinic acid decarboxylase [Source:HGNC Symbol;Acc:HGNC:18966]",{"v":0.772025,"d":"0.77"},0,"inf","inf",1,1,"up","no"]
[59266,0,"chr14","+",104744344,104747325,"ENST00000555884",3,1091,"ENSG00000185100","ADSSL1","GO:0005737(cytoplasm);GO:0005525(GTP binding);GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0016874(ligase activity);GO:0004019(adenylosuccinate synthase activity);GO:0006164(purine nucleotide biosynthetic process);GO:0006167(AMP biosynthetic process);GO:0044208('de novo' AMP biosynthetic process);GO:0002376(immune system process);GO:0005829(cytosol);GO:0009168(purine ribonucleoside monophosphate biosynthetic process);GO:0042301(phosphate ion binding);GO:0046040(IMP metabolic process);GO:0003924(GTPase activity);GO:0042803(protein homodimerization activity);GO:0051015(actin filament binding);GO:0006163(purine nucleotide metabolic process);GO:0006531(aspartate metabolic process);GO:0006541(glutamine metabolic process);GO:0014850(response to muscle activity);GO:0035690(cellular response to drug);GO:0042594(response to starvation);GO:0071257(cellular response to electrical stimulus);GO:0016020(membrane);GO:0016021(integral component of membrane)","00230(Purine metabolism);00250(Alanine, aspartate and glutamate metabolism)","NA","NA","adenylosuccinate synthase like 1 [Source:HGNC Symbol;Acc:HGNC:20093]",0,0,1,0,1,1,"no","no"]
[43939,0,"chr12","+",64781193,64818770,"ENST00000456757",4,596,"ENSG00000111490","TBC1D30","GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0016020(membrane);GO:0005096(GTPase activator activity);GO:0006886(intracellular protein transport);GO:0031338(regulation of vesicle fusion);GO:0090630(activation of GTPase activity);GO:0012505(endomembrane system);GO:0005929(cilium);GO:0043547(positive regulation of GTPase activity);GO:0036064(ciliary basal body);GO:0017137(Rab GTPase binding);GO:1902018(negative regulation of cilium assembly)","NA","NA","NA","TBC1 domain family member 30 [Source:HGNC Symbol;Acc:HGNC:29164]",0,{"v":0.293748,"d":"0.29"},"-inf","-inf",1,1,"down","no"]
[63801,0,"chr15","-",66490306,66497750,"ENST00000395589",4,749,"MSTRG.5228","SNAPC5","GO:0005634(nucleus);GO:0005730(nucleolus);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0006366(transcription from RNA polymerase II promoter);GO:0005515(protein binding);GO:0016604(nuclear body);GO:0006384(transcription initiation from RNA polymerase III promoter);GO:0005654(nucleoplasm);GO:0042795(snRNA transcription from RNA polymerase II promoter)","NA","NA","NA","small nuclear RNA activating complex polypeptide 5 [Source:HGNC Symbol;Acc:HGNC:15484]",{"v":0.208641,"d":"0.21"},{"v":0.622136,"d":"0.62"},{"v":0.335362364499081,"d":"0.34"},{"v":-1.57620730102713,"d":"-1.58"},1,1,"down","no"]
[148714,0,"chr4","-",82818672,82881940,"ENST00000500777",23,3610,"MSTRG.11700","SEC31A","GO:0006810(transport);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0015031(protein transport);GO:0043231(intracellular membrane-bounded organelle);GO:0005829(cytosol);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005515(protein binding);GO:0048471(perinuclear region of cytoplasm);GO:0031410(cytoplasmic vesicle);GO:0016192(vesicle-mediated transport);GO:0000139(Golgi membrane);GO:0048306(calcium-dependent protein binding);GO:0006888(ER to Golgi vesicle-mediated transport);GO:0019886(antigen processing and presentation of exogenous peptide antigen via MHC class II);GO:0048208(COPII vesicle coating);GO:0036498(IRE1-mediated unfolded protein response);GO:0012507(ER to Golgi transport vesicle membrane);GO:0070971(endoplasmic reticulum exit site);GO:0002474(antigen processing and presentation of peptide antigen via MHC class I);GO:0051592(response to calcium ion);GO:0030127(COPII vesicle coat);GO:0090110(cargo loading into COPII-coated vesicle);GO:0030120(vesicle coat);GO:0030134(ER to Golgi transport vesicle)","04141(Protein processing in endoplasmic reticulum)","NA","NA","SEC31 homolog A, COPII coat complex component [Source:HGNC Symbol;Acc:HGNC:17052]",0,0,1,0,1,1,"no","no"]
[197641,0,"chrX","-",54932961,54994078,"ENST00000375006",14,1929,"ENSG00000158571","PFKFB1","GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0016787(hydrolase activity);GO:0003824(catalytic activity);GO:0006096(glycolytic process);GO:0008152(metabolic process);GO:0016311(dephosphorylation);GO:0005515(protein binding);GO:0042802(identical protein binding);GO:0006003(fructose 2,6-bisphosphate metabolic process);GO:0006094(gluconeogenesis);GO:0006000(fructose metabolic process);GO:0003873(6-phosphofructo-2-kinase activity);GO:0005829(cytosol);GO:0004331(fructose-2,6-bisphosphate 2-phosphatase activity);GO:0045821(positive regulation of glycolytic process);GO:0019900(kinase binding);GO:0070095(fructose-6-phosphate binding);GO:0031100(animal organ regeneration);GO:0032868(response to insulin);GO:0033133(positive regulation of glucokinase activity);GO:0033762(response to glucagon);GO:0042594(response to starvation);GO:0045820(negative regulation of glycolytic process);GO:0046835(carbohydrate phosphorylation);GO:0051384(response to glucocorticoid);GO:0051591(response to cAMP);GO:0043540(6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex)","00051(Fructose and mannose metabolism);04152(AMPK signaling pathway);04922(Glucagon signaling pathway)","K19028","EC:2.7.1.105;EC:3.1.3.46","6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 [Source:HGNC Symbol;Acc:HGNC:8872]",{"v":0.090464,"d":"0.09"},{"v":0.010714,"d":"0.01"},{"v":8.4435318275154,"d":"8.44"},{"v":3.07784658711154,"d":"3.08"},1,1,"up","no"]
[94374,0,"chr19","+",1491166,1496181,"ENST00000591735",3,1026,"ENSG00000115255","REEP6","GO:0005634(nucleus);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005515(protein binding);GO:0032386(regulation of intracellular transport);GO:0044317(rod spherule);GO:0045177(apical part of cell);GO:0003674(molecular_function);GO:0008150(biological_process);GO:0050908(detection of light stimulus involved in visual perception);GO:0001917(photoreceptor inner segment)","NA","NA","NA","receptor accessory protein 6 [Source:HGNC Symbol;Acc:HGNC:30078]",0,{"v":0.100383,"d":"0.10"},"-inf","-inf",1,1,"down","no"]
[6263,0,"chr1","-",53851733,53889834,"ENST00000072644",11,1858,"MSTRG.587","YIPF1","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005515(protein binding);GO:0017137(Rab GTPase binding);GO:0005794(Golgi apparatus);GO:0030133(transport vesicle)","NA","NA","NA","Yip1 domain family member 1 [Source:HGNC Symbol;Acc:HGNC:25231]",0,{"v":8.040964,"d":"8.04"},"-inf","-inf",1,1,"down","no"]
[156581,0,"chr5","-",88804526,88883174,"ENST00000511086",3,689,"MSTRG.12209","MEF2C","GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0043231(intracellular membrane-bounded organelle);GO:0005654(nucleoplasm);GO:0046983(protein dimerization activity);GO:0006366(transcription from RNA polymerase II promoter);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0006915(apoptotic process);GO:0007275(multicellular organism development);GO:0007399(nervous system development);GO:0030154(cell differentiation);GO:0000977(RNA polymerase II regulatory region sequence-specific DNA binding);GO:0045893(positive regulation of transcription, DNA-templated);GO:0098794(postsynapse);GO:0030890(positive regulation of B cell proliferation);GO:0048666(neuron development);GO:0071222(cellular response to lipopolysaccharide);GO:0010628(positive regulation of gene expression);GO:0007507(heart development);GO:0009615(response to virus);GO:0043234(protein complex);GO:0030501(positive regulation of bone mineralization);GO:0043524(negative regulation of neuron apoptotic process);GO:0010629(negative regulation of gene expression);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0000165(MAPK cascade);GO:0046982(protein heterodimerization activity);GO:2001016(positive regulation of skeletal muscle cell differentiation);GO:0050853(B cell receptor signaling pathway);GO:0000981(RNA polymerase II transcription factor activity, sequence-specific DNA binding);GO:0035690(cellular response to drug);GO:0071560(cellular response to transforming growth factor beta stimulus);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0044212(transcription regulatory region DNA binding);GO:0003151(outflow tract morphogenesis);GO:0002062(chondrocyte differentiation);GO:0030182(neuron differentiation);GO:0007517(muscle organ development);GO:0001077(transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0001958(endochondral ossification);GO:0071498(cellular response to fluid shear stress);GO:0061333(renal tubule morphogenesis);GO:0072102(glomerulus morphogenesis);GO:0072160(nephron tubule epithelial cell differentiation);GO:2001013(epithelial cell proliferation involved in renal tubule morphogenesis);GO:0071277(cellular response to calcium ion);GO:0001568(blood vessel development);GO:0016607(nuclear speck);GO:0001649(osteoblast differentiation);GO:0051149(positive regulation of muscle cell differentiation);GO:0030318(melanocyte differentiation);GO:0030279(negative regulation of ossification);GO:0006959(humoral immune response);GO:0048643(positive regulation of skeletal muscle tissue development);GO:0001947(heart looping);GO:0007519(skeletal muscle tissue development);GO:0030220(platelet formation);GO:0007611(learning or memory);GO:0042100(B cell proliferation);GO:0045669(positive regulation of osteoblast differentiation);GO:0001782(B cell homeostasis);GO:0045666(positive regulation of neuron differentiation);GO:0000983(transcription factor activity, RNA polymerase II core promoter sequence-specific);GO:0014902(myotube differentiation);GO:0045663(positive regulation of myoblast differentiation);GO:0003680(AT DNA binding);GO:0060045(positive regulation of cardiac muscle cell proliferation);GO:0035198(miRNA binding);GO:0003211(cardiac ventricle formation);GO:0002634(regulation of germinal center formation);GO:0014033(neural crest cell differentiation);GO:0033613(activating transcription factor binding);GO:0045652(regulation of megakaryocyte differentiation);GO:0010694(positive regulation of alkaline phosphatase activity);GO:0001974(blood vessel remodeling);GO:0001764(neuron migration);GO:0002467(germinal center formation);GO:0002931(response to ischemia);GO:0003138(primary heart field specification);GO:0003139(secondary heart field specification);GO:0003185(sinoatrial valve morphogenesis);GO:0007521(muscle cell fate determination);GO:0035984(cellular response to trichostatin A);GO:0043406(positive regulation of MAP kinase activity);GO:0043523(regulation of neuron apoptotic process);GO:0046928(regulation of neurotransmitter secretion);GO:0048167(regulation of synaptic plasticity);GO:0048667(cell morphogenesis involved in neuron differentiation);GO:0051145(smooth muscle cell differentiation);GO:0051963(regulation of synapse assembly);GO:0051966(regulation of synaptic transmission, glutamatergic);GO:0055012(ventricular cardiac muscle cell differentiation);GO:0060025(regulation of synaptic activity);GO:0060079(excitatory postsynaptic potential);GO:0060998(regulation of dendritic spine development);GO:0071374(cellular response to parathyroid hormone stimulus);GO:0090073(positive regulation of protein homodimerization activity);GO:2000111(positive regulation of macrophage apoptotic process);GO:2000310(regulation of NMDA receptor activity);GO:2000311(regulation of AMPA receptor activity);GO:2000727(positive regulation of cardiac muscle cell differentiation);GO:2000987(positive regulation of behavioral fear response);GO:0005829(cytosol);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:0000980(RNA polymerase II distal enhancer sequence-specific DNA binding);GO:0000987(core promoter proximal region sequence-specific DNA binding);GO:0001046(core promoter sequence-specific DNA binding);GO:0001205(transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding);GO:0003682(chromatin binding);GO:0003705(transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding);GO:0042826(histone deacetylase binding);GO:0043565(sequence-specific DNA binding);GO:0071837(HMG box domain binding);GO:0014898(cardiac muscle hypertrophy in response to stress);GO:0021542(dentate gyrus development);GO:0030224(monocyte differentiation);GO:0031667(response to nutrient levels);GO:0033197(response to vitamin E);GO:0035914(skeletal muscle cell differentiation);GO:0045165(cell fate commitment);GO:0048703(embryonic viscerocranium morphogenesis);GO:0048704(embryonic skeletal system morphogenesis);GO:0050680(negative regulation of epithelial cell proliferation);GO:0055007(cardiac muscle cell differentiation);GO:0060021(palate development);GO:0060290(transdifferentiation);GO:0060297(regulation of sarcomere organization);GO:0060536(cartilage morphogenesis);GO:0071300(cellular response to retinoic acid);GO:0071333(cellular response to glucose stimulus);GO:0071407(cellular response to organic cyclic compound);GO:0071864(positive regulation of cell proliferation in bone marrow)","04010(MAPK signaling pathway);04371(Apelin signaling pathway);04022(cGMP - PKG signaling pathway);04921(Oxytocin signaling pathway);05202(Transcriptional misregulation in cancers);05418(Fluid shear stress and atherosclerosis)","NA","NA","myocyte enhancer factor 2C [Source:HGNC Symbol;Acc:HGNC:6996]",{"v":0.110606,"d":"0.11"},{"v":0.070202,"d":"0.07"},{"v":1.57553915842853,"d":"1.58"},{"v":0.655845611523719,"d":"0.66"},1,1,"up","no"]
[136546,0,"chr3","+",50059698,50065061,"ENST00000438912",7,473,"MSTRG.10947","RBM6","GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005515(protein binding);GO:0003677(DNA binding);GO:0006396(RNA processing)","NA","NA","NA","RNA binding motif protein 6 [Source:HGNC Symbol;Acc:HGNC:9903]",{"v":0.21113,"d":"0.21"},0,"inf","inf",1,1,"up","no"]
[32311,0,"chr11","+",68934331,68936446,"ENST00000545475",3,562,"MSTRG.2636","IGHMBP2","GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0006412(translation);GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0016787(hydrolase activity);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0004386(helicase activity);GO:0032508(DNA duplex unwinding);GO:0030529(intracellular ribonucleoprotein complex);GO:0042995(cell projection);GO:0000049(tRNA binding);GO:0043022(ribosome binding);GO:0005515(protein binding);GO:0030424(axon);GO:0030426(growth cone);GO:0008134(transcription factor binding);GO:0051260(protein homooligomerization);GO:0006281(DNA repair);GO:0008094(DNA-dependent ATPase activity);GO:0006310(DNA recombination);GO:0006260(DNA replication);GO:0003678(DNA helicase activity);GO:0003697(single-stranded DNA binding);GO:0008186(RNA-dependent ATPase activity);GO:0032575(ATP-dependent 5'-3' RNA helicase activity);GO:0043141(ATP-dependent 5'-3' DNA helicase activity)","NA","NA","NA","immunoglobulin mu binding protein 2 [Source:HGNC Symbol;Acc:HGNC:5542]",{"v":0.013616,"d":"0.01"},{"v":0.004305,"d":"0.00"},{"v":3.16283391405343,"d":"3.16"},{"v":1.66121779940176,"d":"1.66"},1,1,"up","no"]
[45671,0,"chr12","+",100200817,100206258,"ENST00000550813",4,351,"ENSG00000075089","ACTR6","GO:0005634(nucleus);GO:0006338(chromatin remodeling);GO:0005737(cytoplasm);GO:0005856(cytoskeleton);GO:0005515(protein binding)","NA","NA","NA","ARP6 actin related protein 6 homolog [Source:HGNC Symbol;Acc:HGNC:24025]",0,0,1,0,1,1,"no","no"]
[124235,0,"chr20","-",45842023,45849110,"ENST00000484975",2,3059,"MSTRG.9779","ACOT8","GO:0005737(cytoplasm);GO:0016787(hydrolase activity);GO:0005515(protein binding);GO:0005777(peroxisome);GO:0006637(acyl-CoA metabolic process);GO:0052689(carboxylic ester hydrolase activity);GO:0016032(viral process);GO:0005102(receptor binding);GO:0047617(acyl-CoA hydrolase activity);GO:0005782(peroxisomal matrix);GO:0016290(palmitoyl-CoA hydrolase activity);GO:0016559(peroxisome fission);GO:0007031(peroxisome organization);GO:0003986(acetyl-CoA hydrolase activity);GO:0016289(CoA hydrolase activity);GO:0033882(choloyl-CoA hydrolase activity);GO:0052815(medium-chain acyl-CoA hydrolase activity);GO:0006699(bile acid biosynthetic process);GO:0009062(fatty acid catabolic process);GO:0033540(fatty acid beta-oxidation using acyl-CoA oxidase);GO:0036109(alpha-linolenic acid metabolic process);GO:0043649(dicarboxylic acid catabolic process);GO:0045225(negative regulation of CD4 biosynthetic process);GO:0005739(mitochondrion)","00120(Primary bile acid biosynthesis);04146(Peroxisome)","NA","NA","acyl-CoA thioesterase 8 [Source:HGNC Symbol;Acc:HGNC:15919]",{"v":0.043178,"d":"0.04"},{"v":0.10704,"d":"0.11"},{"v":0.403381913303438,"d":"0.40"},{"v":-1.3097816965399,"d":"-1.31"},1,1,"down","no"]
[42974,0,"chr12","-",56202504,56221701,"ENST00000615206",7,5216,"MSTRG.3456","RNF41","GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0016740(transferase activity);GO:0016567(protein ubiquitination);GO:0005515(protein binding);GO:0006915(apoptotic process);GO:0006914(autophagy);GO:0005128(erythropoietin receptor binding);GO:0005135(interleukin-3 receptor binding);GO:0016881(acid-amino acid ligase activity);GO:0031386(protein tag);GO:0000209(protein polyubiquitination);GO:0010468(regulation of gene expression);GO:0045619(regulation of lymphocyte differentiation);GO:0045637(regulation of myeloid cell differentiation);GO:0051091(positive regulation of sequence-specific DNA binding transcription factor activity);GO:1901525(negative regulation of macromitophagy);GO:2000114(regulation of establishment of cell polarity);GO:0005829(cytosol);GO:0017160(Ral GTPase binding);GO:0097191(extrinsic apoptotic signaling pathway);GO:0004842(ubiquitin-protein transferase activity);GO:0019904(protein domain specific binding);GO:0051865(protein autoubiquitination);GO:0061630(ubiquitin protein ligase activity);GO:2000377(regulation of reactive oxygen species metabolic process);GO:0010498(proteasomal protein catabolic process);GO:0048471(perinuclear region of cytoplasm);GO:0008285(negative regulation of cell proliferation);GO:0030336(negative regulation of cell migration);GO:0030971(receptor tyrosine kinase binding);GO:0043408(regulation of MAPK cascade);GO:0045732(positive regulation of protein catabolic process);GO:0051896(regulation of protein kinase B signaling);GO:2000379(positive regulation of reactive oxygen species metabolic process);GO:0071782(endoplasmic reticulum tubular network)","04144(Endocytosis)","K11981","EC:2.3.2.27","ring finger protein 41 [Source:HGNC Symbol;Acc:HGNC:18401]",0,0,1,0,1,1,"no","no"]
[145457,0,"chr4","+",2907830,2928560,"ENST00000536424",4,594,"MSTRG.11508","ADD1","GO:0005856(cytoskeleton);GO:0005634(nucleus);GO:0030036(actin cytoskeleton organization);GO:0003723(RNA binding);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005654(nucleoplasm);GO:0003779(actin binding);GO:0005886(plasma membrane);GO:0016604(nuclear body);GO:0005925(focal adhesion);GO:0005516(calmodulin binding);GO:0005829(cytosol);GO:0045296(cadherin binding);GO:0055085(transmembrane transport);GO:0042803(protein homodimerization activity);GO:0046982(protein heterodimerization activity);GO:0036498(IRE1-mediated unfolded protein response);GO:0032092(positive regulation of protein binding);GO:0008134(transcription factor binding);GO:0051015(actin filament binding);GO:0030507(spectrin binding);GO:0005913(cell-cell adherens junction);GO:0051016(barbed-end actin filament capping);GO:0051017(actin filament bundle assembly);GO:0071277(cellular response to calcium ion);GO:1903142(positive regulation of establishment of endothelial barrier);GO:1903393(positive regulation of adherens junction organization);GO:0008290(F-actin capping protein complex);GO:0005198(structural molecule activity);GO:0000902(cell morphogenesis);GO:0001701(in utero embryonic development);GO:0006884(cell volume homeostasis);GO:0020027(hemoglobin metabolic process);GO:0030218(erythrocyte differentiation);GO:0035264(multicellular organism growth);GO:0048873(homeostasis of number of cells within a tissue)","NA","NA","NA","adducin 1 [Source:HGNC Symbol;Acc:HGNC:243]",{"v":0.057541,"d":"0.06"},{"v":0.113464,"d":"0.11"},{"v":0.507130014806458,"d":"0.51"},{"v":-0.979572431149406,"d":"-0.98"},1,1,"down","no"]
[24059,0,"chr10","+",122386609,122430479,"ENST00000392799",13,3221,"ENSG00000107679","PLEKHA1","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0008289(lipid binding);GO:0070062(extracellular exosome);GO:0032587(ruffle membrane);GO:0043325(phosphatidylinositol-3,4-bisphosphate binding);GO:0006661(phosphatidylinositol biosynthetic process);GO:0014065(phosphatidylinositol 3-kinase signaling);GO:0050853(B cell receptor signaling pathway);GO:0030165(PDZ domain binding);GO:0051898(negative regulation of protein kinase B signaling);GO:0045184(establishment of protein localization);GO:0070301(cellular response to hydrogen peroxide);GO:0031529(ruffle organization);GO:0001553(luteinization);GO:0007283(spermatogenesis);GO:0008209(androgen metabolic process);GO:0008210(estrogen metabolic process);GO:0008585(female gonad development);GO:0009791(post-embryonic development);GO:0033327(Leydig cell differentiation);GO:0035264(multicellular organism growth);GO:0048008(platelet-derived growth factor receptor signaling pathway);GO:0048705(skeletal system morphogenesis);GO:0060021(palate development);GO:0060325(face morphogenesis)","NA","NA","NA","pleckstrin homology domain containing A1 [Source:HGNC Symbol;Acc:HGNC:14335]",{"v":0.017032,"d":"0.02"},{"v":0.101253,"d":"0.10"},{"v":0.168212299882473,"d":"0.17"},{"v":-2.57164489386824,"d":"-2.57"},1,1,"down","no"]
[53742,0,"chr14","-",24318349,24335071,"ENST00000557056",21,3990,"ENSG00000129467","ADCY4","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0035556(intracellular signal transduction);GO:0016829(lyase activity);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0016849(phosphorus-oxygen lyase activity);GO:0006171(cAMP biosynthetic process);GO:0009190(cyclic nucleotide biosynthetic process);GO:0007165(signal transduction);GO:0007193(adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway);GO:0004016(adenylate cyclase activity);GO:0004383(guanylate cyclase activity);GO:0003091(renal water homeostasis);GO:0006182(cGMP biosynthetic process);GO:0007189(adenylate cyclase-activating G-protein coupled receptor signaling pathway);GO:0007190(activation of adenylate cyclase activity);GO:0034199(activation of protein kinase A activity);GO:0071377(cellular response to glucagon stimulus);GO:0008074(guanylate cyclase complex, soluble);GO:0007188(adenylate cyclase-modulating G-protein coupled receptor signaling pathway);GO:0005622(intracellular);GO:0030425(dendrite)","00230(Purine metabolism);04015(Rap1 signaling pathway);04371(Apelin signaling pathway);04020(Calcium signaling pathway);04072(Phospholipase D signaling pathway);04024(cAMP signaling pathway);04022(cGMP - PKG signaling pathway);04114(Oocyte meiosis);04540(Gap junction);04611(Platelet activation);04062(Chemokine signaling pathway);04911(Insulin secretion);04923(Regulation of lipolysis in adipocyte);04912(GnRH signaling pathway);04913(Ovarian Steroidogenesis);04915(Estrogen signaling pathway);04914(Progesterone-mediated oocyte maturation);04921(Oxytocin signaling pathway);04926(Relaxin signaling pathway);04918(Thyroid hormone synthesis);04916(Melanogenesis);04925(Aldosterone synthesis and secretion);04927(Cortisol synthesis and secretion);04261(Adrenergic signaling in cardiomyocytes);04270(Vascular smooth muscle contraction);04970(Salivary secretion);04971(Gastric acid secretion);04972(Pancreatic secretion);04976(Bile secretion);04724(Glutamatergic synapse);04727(GABAergic synapse);04725(Cholinergic synapse);04723(Retrograde endocannabinoid signaling);04742(Taste transduction);04750(Inflammatory mediator regulation of TRP channels);04211(Longevity regulating pathway - mammal);04213(Longevity regulating pathway - multiple species);04713(Circadian entrainment);05200(Pathways in cancer);05032(Morphine addiction);05414(Dilated cardiomyopathy (DCM));05166(HTLV-I infection);01522(Endocrine resistance)","NA","NA","adenylate cyclase 4 [Source:HGNC Symbol;Acc:HGNC:235]",{"v":0.217576,"d":"0.22"},{"v":0.024496,"d":"0.02"},{"v":8.88210320052253,"d":"8.88"},{"v":3.15090133397302,"d":"3.15"},1,1,"up","no"]
[32826,0,"chr11","-",72754843,72781116,"ENST00000538437",5,747,"MSTRG.2689","STARD10","GO:0008289(lipid binding);GO:0006810(transport);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0042995(cell projection);GO:0005515(protein binding);GO:0006869(lipid transport);GO:0005829(cytosol);GO:0006656(phosphatidylcholine biosynthetic process);GO:0005902(microvillus);GO:0046581(intercellular canaliculus);GO:0032782(bile acid secretion);GO:0035360(positive regulation of peroxisome proliferator activated receptor signaling pathway)","NA","NA","NA","StAR related lipid transfer domain containing 10 [Source:HGNC Symbol;Acc:HGNC:10666]",0,0,1,0,1,1,"no","no"]
[151532,0,"chr4","-",152146385,152178573,"ENST00000504799",5,552,"ENSG00000250706","AC079340.1","NA","NA","NA","NA","NA",0,0,1,0,1,1,"no","no"]
[71406,0,"chr16","+",28936799,28939218,"ENST00000567368",7,847,"ENSG00000177455","CD19","GO:0005622(intracellular);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005515(protein binding);GO:0030449(regulation of complement activation);GO:0050776(regulation of immune response);GO:0005886(plasma membrane);GO:0050853(B cell receptor signaling pathway);GO:0046854(phosphatidylinositol phosphorylation);GO:0070062(extracellular exosome);GO:0005887(integral component of plasma membrane);GO:0043234(protein complex);GO:0007166(cell surface receptor signaling pathway);GO:0046934(phosphatidylinositol-4,5-bisphosphate 3-kinase activity);GO:0014066(regulation of phosphatidylinositol 3-kinase signaling);GO:0038111(interleukin-7-mediated signaling pathway);GO:0048015(phosphatidylinositol-mediated signaling);GO:0005057(signal transducer activity, downstream of receptor);GO:0006968(cellular defense response);GO:0009897(external side of plasma membrane);GO:0051281(positive regulation of release of sequestered calcium ion into cytosol)","04151(PI3K-Akt signaling pathway);04640(Hematopoietic cell lineage);04662(B cell receptor signaling pathway);05340(Primary immunodeficiency);05169(Epstein-Barr virus infection)","NA","NA","CD19 molecule [Source:HGNC Symbol;Acc:HGNC:1633]",0,{"v":0.053865,"d":"0.05"},"-inf","-inf",1,1,"down","no"]
[90817,0,"chr18","-",12067173,12068417,"ENST00000589764",2,1148,"ENSG00000267533","AP002414.4","NA","NA","NA","NA","NA",{"v":0.091662,"d":"0.09"},0,"inf","inf",1,1,"up","no"]
[145219,0,"chr4","-",1693244,1712018,"ENST00000483348",6,1030,"MSTRG.11491","SLBP","GO:0003723(RNA binding);GO:0003729(mRNA binding);GO:0006397(mRNA processing);GO:0051028(mRNA transport);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005730(nucleolus);GO:0005829(cytosol);GO:0030529(intracellular ribonucleoprotein complex);GO:0005515(protein binding);GO:0005654(nucleoplasm);GO:0006369(termination of RNA polymerase II transcription);GO:0006406(mRNA export from nucleus);GO:0071204(histone pre-mRNA 3'end processing complex);GO:0044770(cell cycle phase transition);GO:0008334(histone mRNA metabolic process);GO:0071208(histone pre-mRNA DCP binding);GO:0006398(mRNA 3'-end processing by stem-loop binding and cleavage);GO:0071207(histone pre-mRNA stem-loop binding);GO:0033260(nuclear DNA replication)","NA","NA","NA","stem-loop binding protein [Source:HGNC Symbol;Acc:HGNC:10904]",{"v":0.078312,"d":"0.08"},0,"inf","inf",1,1,"up","no"]
[53837,0,"chr14","-",24573522,24576250,"ENST00000552252",4,1364,"ENSG00000100448","CTSG","GO:0005615(extracellular space);GO:0005634(nucleus);GO:0016787(hydrolase activity);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0008233(peptidase activity);GO:0006508(proteolysis);GO:0004252(serine-type endopeptidase activity);GO:0008236(serine-type peptidase activity);GO:0005576(extracellular region);GO:0042742(defense response to bacterium);GO:0070062(extracellular exosome);GO:0050829(defense response to Gram-negative bacterium);GO:0071222(cellular response to lipopolysaccharide);GO:0044267(cellular protein metabolic process);GO:0031012(extracellular matrix);GO:0019731(antibacterial humoral response);GO:0043312(neutrophil degranulation);GO:0010494(cytoplasmic stress granule);GO:0006955(immune response);GO:0009986(cell surface);GO:0019730(antimicrobial humoral response);GO:0035578(azurophil granule lumen);GO:0022617(extracellular matrix disassembly);GO:0002003(angiotensin maturation);GO:0008201(heparin binding);GO:0030141(secretory granule);GO:0006468(protein phosphorylation);GO:0032496(response to lipopolysaccharide);GO:0044130(negative regulation of growth of symbiont in host);GO:0050778(positive regulation of immune response);GO:0050830(defense response to Gram-positive bacterium);GO:0050832(defense response to fungus);GO:0070946(neutrophil mediated killing of gram-positive bacterium)","04080(Neuroactive ligand-receptor interaction);04142(Lysosome);04614(Renin-angiotensin system);05322(Systemic lupus erythematosus);05146(Amoebiasis)","NA","NA","cathepsin G [Source:HGNC Symbol;Acc:HGNC:2532]",{"v":0.130367,"d":"0.13"},{"v":0.113407,"d":"0.11"},{"v":1.14954985142011,"d":"1.15"},{"v":0.20106903137762,"d":"0.20"},1,1,"up","no"]
[46207,0,"chr12","+",107692683,107697584,"ENST00000547120",4,543,"MSTRG.3677","PWP1","GO:0005634(nucleus);GO:0005794(Golgi apparatus);GO:0005730(nucleolus);GO:1990889(H4K20me3 modified histone binding);GO:0033140(negative regulation of peptidyl-serine phosphorylation of STAT protein);GO:0034773(histone H4-K20 trimethylation);GO:2000738(positive regulation of stem cell differentiation);GO:0006351(transcription, DNA-templated)","NA","NA","NA","PWP1 homolog, endonuclein [Source:HGNC Symbol;Acc:HGNC:17015]",{"v":0.410725,"d":"0.41"},{"v":0.026282,"d":"0.03"},{"v":15.6276158587627,"d":"15.63"},{"v":3.96602579318031,"d":"3.97"},1,1,"up","no"]
[102789,0,"chr19","-",45485294,45493267,"ENST00000430715",7,1127,"ENSG00000125744","RTN2","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005515(protein binding);GO:0030176(integral component of endoplasmic reticulum membrane);GO:0046324(regulation of glucose import);GO:0065002(intracellular protein transmembrane transport);GO:0014802(terminal cisterna);GO:0030315(T-tubule)","NA","NA","NA","reticulon 2 [Source:HGNC Symbol;Acc:HGNC:10468]",{"v":1.123267,"d":"1.12"},0,"inf","inf",1,1,"up","no"]
[105589,0,"chr19","+",54647944,54648853,"ENST00000486595",1,910,"ENSG00000242856","VN1R105P","NA","NA","NA","NA","vomeronasal 1 receptor 105 pseudogene [Source:HGNC Symbol;Acc:HGNC:37428]",0,0,1,0,1,1,"no","no"]
[4916,0,"chr1","-",42746374,42766989,"ENST00000460031",14,2726,"MSTRG.476","P3H1","GO:0016020(membrane);GO:0046872(metal ion binding);GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0005783(endoplasmic reticulum);GO:0005506(iron ion binding);GO:0016705(oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen);GO:0031418(L-ascorbic acid binding);GO:0005576(extracellular region);GO:0005578(proteinaceous extracellular matrix);GO:0051213(dioxygenase activity);GO:0003674(molecular_function);GO:0070062(extracellular exosome);GO:0050821(protein stabilization);GO:0060348(bone development);GO:0008285(negative regulation of cell proliferation);GO:0019511(peptidyl-proline hydroxylation);GO:0006457(protein folding);GO:0005788(endoplasmic reticulum lumen);GO:0032403(protein complex binding);GO:0061077(chaperone-mediated protein folding);GO:0005518(collagen binding);GO:1901874(negative regulation of post-translational protein modification);GO:0032991(macromolecular complex);GO:0050708(regulation of protein secretion);GO:0032963(collagen metabolic process);GO:0018126(protein hydroxylation);GO:0019797(procollagen-proline 3-dioxygenase activity)","NA","NA","NA","prolyl 3-hydroxylase 1 [Source:HGNC Symbol;Acc:HGNC:19316]",{"v":1.242105,"d":"1.24"},{"v":0.061619,"d":"0.06"},{"v":20.1578246969279,"d":"20.16"},{"v":4.33326805573506,"d":"4.33"},1,1,"up","no"]
[61741,0,"chr15","+",43371073,43377903,"ENST00000563517",5,771,"ENSG00000137822","TUBGCP4","GO:0000226(microtubule cytoskeleton organization);GO:0005815(microtubule organizing center);GO:0043015(gamma-tubulin binding);GO:0007020(microtubule nucleation);GO:0000922(spindle pole);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005813(centrosome);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0005874(microtubule);GO:0005200(structural constituent of cytoskeleton);GO:0005829(cytosol);GO:0031122(cytoplasmic microtubule organization);GO:0055037(recycling endosome);GO:0006461(protein complex assembly);GO:0090307(mitotic spindle assembly);GO:0015630(microtubule cytoskeleton);GO:0008274(gamma-tubulin ring complex);GO:0051415(interphase microtubule nucleation by interphase microtubule organizing center);GO:0000923(equatorial microtubule organizing center);GO:0051298(centrosome duplication);GO:0051321(meiotic cell cycle);GO:0051011(microtubule minus-end binding);GO:0000930(gamma-tubulin complex)","NA","NA","NA","tubulin gamma complex associated protein 4 [Source:HGNC Symbol;Acc:HGNC:16691]",0,0,1,0,1,1,"no","no"]
[45769,0,"chr12","+",101594971,101686018,"ENST00000549145",31,4031,"ENSG00000196091","MYBPC1","GO:0007155(cell adhesion);GO:0003779(actin binding);GO:0005515(protein binding);GO:0005829(cytosol);GO:0051015(actin filament binding);GO:0051371(muscle alpha-actinin binding);GO:0097493(structural molecule activity conferring elasticity);GO:0006941(striated muscle contraction);GO:0007015(actin filament organization);GO:0045214(sarcomere organization);GO:0071688(striated muscle myosin thick filament assembly);GO:0005859(muscle myosin complex);GO:0030018(Z disc);GO:0031430(M band);GO:0032982(myosin filament);GO:1903955(positive regulation of protein targeting to mitochondrion);GO:0008307(structural constituent of muscle);GO:0031432(titin binding);GO:0030049(muscle filament sliding);GO:0030016(myofibril);GO:0006936(muscle contraction)","NA","NA","NA","myosin binding protein C, slow type [Source:HGNC Symbol;Acc:HGNC:7549]",{"v":0.023635,"d":"0.02"},{"v":0.0142,"d":"0.01"},{"v":1.66443661971831,"d":"1.66"},{"v":0.735033934966605,"d":"0.74"},1,1,"up","no"]
[141904,"j","chr3","+",155138100,155183549,"MSTRG.11292.18",14,4734,"MSTRG.11292","MME","NA","NA","NA","NA","NA",{"v":0.039642,"d":"0.04"},{"v":1.808422,"d":"1.81"},{"v":0.0219207684931946,"d":"0.02"},{"v":-5.51155781292308,"d":"-5.51"},1,1,"down","no"]
[76456,0,"chr16","+",85792415,85792933,"ENST00000602617",2,408,"MSTRG.6208","AC018695.3","NA","NA","NA","NA","NA",0,0,1,0,1,1,"no","no"]
[176310,0,"chr7","-",96486273,96709775,"ENST00000613919",6,610,"MSTRG.13780","SEM1","GO:0006406(mRNA export from nucleus);GO:0043248(proteasome assembly);GO:0008541(proteasome regulatory particle, lid subcomplex);GO:0005515(protein binding);GO:0000502(proteasome complex);GO:0038095(Fc-epsilon receptor signaling pathway);GO:0005654(nucleoplasm);GO:0005829(cytosol);GO:0000165(MAPK cascade);GO:0000209(protein polyubiquitination);GO:0002223(stimulatory C-type lectin receptor signaling pathway);GO:0002479(antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent);GO:0006521(regulation of cellular amino acid metabolic process);GO:0010972(negative regulation of G2/M transition of mitotic cell cycle);GO:0016579(protein deubiquitination);GO:0031145(anaphase-promoting complex-dependent catabolic process);GO:0031146(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process);GO:0033209(tumor necrosis factor-mediated signaling pathway);GO:0038061(NIK/NF-kappaB signaling);GO:0043161(proteasome-mediated ubiquitin-dependent protein catabolic process);GO:0043488(regulation of mRNA stability);GO:0043687(post-translational protein modification);GO:0050852(T cell receptor signaling pathway);GO:0051437(positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition);GO:0055085(transmembrane transport);GO:0060071(Wnt signaling pathway, planar cell polarity pathway);GO:0061418(regulation of transcription from RNA polymerase II promoter in response to hypoxia);GO:0090090(negative regulation of canonical Wnt signaling pathway);GO:0090263(positive regulation of canonical Wnt signaling pathway);GO:1902036(regulation of hematopoietic stem cell differentiation);GO:0051436(negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle);GO:0032039(integrator complex)","03050(Proteasome);03440(Homologous recombination);05169(Epstein-Barr virus infection)","NA","NA","SEM1, 26S proteasome complex subunit [Source:HGNC Symbol;Acc:HGNC:10845]",0,0,1,0,1,1,"no","no"]
[55477,0,"chr14","+",58427728,58444019,"ENST00000554463",6,582,"ENSG00000100578","KIAA0586","GO:0005737(cytoplasm);GO:0005856(cytoskeleton);GO:0042995(cell projection);GO:0005813(centrosome);GO:0005815(microtubule organizing center);GO:0007224(smoothened signaling pathway);GO:0060271(cilium assembly);GO:0030030(cell projection organization);GO:0005814(centriole);GO:0001917(photoreceptor inner segment);GO:0070201(regulation of establishment of protein localization);GO:0036064(ciliary basal body)","NA","NA","NA","KIAA0586 [Source:HGNC Symbol;Acc:HGNC:19960]",{"v":0.204849,"d":"0.20"},{"v":0.518049,"d":"0.52"},{"v":0.395423984989837,"d":"0.40"},{"v":-1.33852771249898,"d":"-1.34"},1,1,"down","no"]
[46852,0,"chr12","+",112256800,112259091,"ENST00000547401",2,751,"ENSG00000257494","AC004217.2","NA","NA","NA","NA","NA",0,0,1,0,1,1,"no","no"]
[1200,0,"chr1","+",7803051,7810347,"ENST00000463106",3,715,"ENSG00000049246","PER3","GO:0032922(circadian regulation of gene expression);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0005515(protein binding);GO:0048511(rhythmic process);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0050821(protein stabilization);GO:0045187(regulation of circadian sleep/wake cycle, sleep);GO:0019900(kinase binding);GO:0031625(ubiquitin protein ligase binding);GO:0007623(circadian rhythm)","04710(Circadian rhythm);04713(Circadian entrainment);05168(Herpes simplex infection)","NA","NA","period circadian clock 3 [Source:HGNC Symbol;Acc:HGNC:8847]",0,0,1,0,1,1,"no","no"]
[178791,0,"chr7","-",130546787,130668705,"ENST00000330992",20,3073,"ENSG00000158623","COPG2","GO:0006810(transport);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0006886(intracellular protein transport);GO:0015031(protein transport);GO:0016192(vesicle-mediated transport);GO:0030117(membrane coat);GO:0005794(Golgi apparatus);GO:0005198(structural molecule activity);GO:0005829(cytosol);GO:0000139(Golgi membrane);GO:0031410(cytoplasmic vesicle);GO:0030126(COPI vesicle coat);GO:0030663(COPI-coated vesicle membrane);GO:0005789(endoplasmic reticulum membrane);GO:0006890(retrograde vesicle-mediated transport, Golgi to ER);GO:0006888(ER to Golgi vesicle-mediated transport);GO:0030133(transport vesicle);GO:0006891(intra-Golgi vesicle-mediated transport)","NA","NA","NA","coatomer protein complex subunit gamma 2 [Source:HGNC Symbol;Acc:HGNC:2237]",0,0,1,0,1,1,"no","no"]
[167104,0,"chr6","+",70667776,70862015,"ENST00000370455",11,3333,"MSTRG.13114","SMAP1","GO:0016020(membrane);GO:0046872(metal ion binding);GO:0005886(plasma membrane);GO:0043547(positive regulation of GTPase activity);GO:0005096(GTPase activator activity);GO:0030276(clathrin binding);GO:0045648(positive regulation of erythrocyte differentiation);GO:2000369(regulation of clathrin-dependent endocytosis);GO:0005737(cytoplasm)","04144(Endocytosis)","K12486","NA","small ArfGAP 1 [Source:HGNC Symbol;Acc:HGNC:19651]",0,{"v":0.021451,"d":"0.02"},"-inf","-inf",1,1,"down","no"]
[26632,0,"chr11","-",10581906,10693522,"ENST00000526414",17,1650,"MSTRG.2251","MRVI1","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0048471(perinuclear region of cytoplasm);GO:0005515(protein binding);GO:0016529(sarcoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0031095(platelet dense tubular network membrane)","04022(cGMP - PKG signaling pathway);04270(Vascular smooth muscle contraction)","NA","NA","murine retrovirus integration site 1 homolog [Source:HGNC Symbol;Acc:HGNC:7237]",0,0,1,0,1,1,"no","no"]
[125512,0,"chr20","+",63658312,63696253,"ENST00000360203",35,4623,"MSTRG.9911","RTEL1","GO:0005634(nucleus);GO:0003676(nucleic acid binding);GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0016787(hydrolase activity);GO:0003677(DNA binding);GO:0004003(ATP-dependent DNA helicase activity);GO:0004386(helicase activity);GO:0008026(ATP-dependent helicase activity);GO:0016818(hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides);GO:0006139(nucleobase-containing compound metabolic process);GO:0006281(DNA repair);GO:0000723(telomere maintenance);GO:0006974(cellular response to DNA damage stimulus);GO:0006260(DNA replication);GO:0051536(iron-sulfur cluster binding);GO:0051539(4 iron, 4 sulfur cluster binding);GO:0006310(DNA recombination);GO:0005515(protein binding);GO:0005654(nucleoplasm);GO:0010569(regulation of double-strand break repair via homologous recombination);GO:1904355(positive regulation of telomere capping);GO:0000781(chromosome, telomeric region);GO:0000732(strand displacement);GO:0090657(telomeric loop disassembly);GO:0032206(positive regulation of telomere maintenance);GO:0032508(DNA duplex unwinding);GO:0031297(replication fork processing);GO:1902990(mitotic telomere maintenance via semi-conservative replication);GO:1904430(negative regulation of t-circle formation);GO:0045910(negative regulation of DNA recombination);GO:1904358(positive regulation of telomere maintenance via telomere lengthening);GO:0043247(telomere maintenance in response to DNA damage);GO:1904506(negative regulation of telomere maintenance in response to DNA damage);GO:1904535(positive regulation of telomeric loop disassembly)","NA","NA","NA","regulator of telomere elongation helicase 1 [Source:HGNC Symbol;Acc:HGNC:15888]",0,0,1,0,1,1,"no","no"]
[31631,0,"chr11","-",66341949,66345125,"ENST00000529544",2,447,"MSTRG.2586","BRMS1","GO:0009987(cellular process);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0005515(protein binding);GO:0006915(apoptotic process);GO:0005654(nucleoplasm);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0032088(negative regulation of NF-kappaB transcription factor activity);GO:0042981(regulation of apoptotic process);GO:0045892(negative regulation of transcription, DNA-templated);GO:0004407(histone deacetylase activity);GO:0051059(NF-kappaB binding);GO:0042826(histone deacetylase binding);GO:0016575(histone deacetylation);GO:2000210(positive regulation of anoikis);GO:0070822(Sin3-type complex);GO:0090312(positive regulation of protein deacetylation)","NA","NA","NA","breast cancer metastasis suppressor 1 [Source:HGNC Symbol;Acc:HGNC:17262]",{"v":0.797074,"d":"0.80"},{"v":0.559316,"d":"0.56"},{"v":1.42508707063628,"d":"1.43"},{"v":0.511050068426574,"d":"0.51"},1,1,"up","no"]
[47881,0,"chr12","-",122701293,122703343,"ENST00000328880",1,2051,"MSTRG.3826","HCAR2","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0004930(G-protein coupled receptor activity);GO:0007186(G-protein coupled receptor signaling pathway);GO:0005886(plasma membrane);GO:0030054(cell junction);GO:0004871(signal transducer activity);GO:0007165(signal transduction);GO:0006915(apoptotic process);GO:0001781(neutrophil apoptotic process);GO:0050995(negative regulation of lipid catabolic process);GO:0070553(nicotinic acid receptor activity);GO:0033031(positive regulation of neutrophil apoptotic process);GO:0070165(positive regulation of adiponectin secretion)","04024(cAMP signaling pathway)","K08402","NA","hydroxycarboxylic acid receptor 2 [Source:HGNC Symbol;Acc:HGNC:24827]",0,{"v":8.753082,"d":"8.75"},"-inf","-inf",1,1,"down","no"]
[58964,0,"chr14","-",102943813,102945724,"ENST00000559245",2,738,"ENSG00000198752","CDC42BPB","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0035556(intracellular signal transduction);GO:0005886(plasma membrane);GO:0030036(actin cytoskeleton organization);GO:0000287(magnesium ion binding);GO:0030054(cell junction);GO:0017048(Rho GTPase binding);GO:0016477(cell migration);GO:0031032(actomyosin structure organization);GO:0042641(actomyosin);GO:0031252(cell leading edge);GO:0070062(extracellular exosome);GO:0007165(signal transduction);GO:0005856(cytoskeleton);GO:0005911(cell-cell junction);GO:0007010(cytoskeleton organization);GO:0031532(actin cytoskeleton reorganization);GO:0007163(establishment or maintenance of cell polarity);GO:0005622(intracellular)","NA","NA","NA","CDC42 binding protein kinase beta [Source:HGNC Symbol;Acc:HGNC:1738]",0,0,1,0,1,1,"no","no"]
[157950,0,"chr5","-",127051304,127073467,"ENST00000607731",5,478,"ENSG00000164241","C5orf63","GO:0055114(oxidation-reduction process)","NA","NA","NA","chromosome 5 open reading frame 63 [Source:HGNC Symbol;Acc:HGNC:40051]",0,0,1,0,1,1,"no","no"]
[141893,0,"chr3","+",155080021,155090499,"ENST00000616757",3,1319,"MSTRG.11292","MME","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0046872(metal ion binding);GO:0016787(hydrolase activity);GO:0008270(zinc ion binding);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0008233(peptidase activity);GO:0006508(proteolysis);GO:0045202(synapse);GO:0004222(metalloendopeptidase activity);GO:0008237(metallopeptidase activity);GO:0005925(focal adhesion);GO:0030425(dendrite);GO:0005887(integral component of plasma membrane);GO:0030424(axon);GO:0070062(extracellular exosome);GO:0005903(brush border);GO:0043312(neutrophil degranulation);GO:0030667(secretory granule membrane);GO:0008021(synaptic vesicle);GO:0004175(endopeptidase activity);GO:0042277(peptide binding);GO:0071493(cellular response to UV-B);GO:0001822(kidney development);GO:0071345(cellular response to cytokine stimulus);GO:0019233(sensory perception of pain);GO:0002003(angiotensin maturation);GO:0008238(exopeptidase activity);GO:0006518(peptide metabolic process);GO:0046449(creatinine metabolic process);GO:0050435(amyloid-beta metabolic process);GO:0071492(cellular response to UV-A);GO:0090399(replicative senescence);GO:0044306(neuron projection terminus)","04640(Hematopoietic cell lineage);04614(Renin-angiotensin system);04974(Protein digestion and absorption);05010(Alzheimer's disease)","NA","NA","membrane metalloendopeptidase [Source:HGNC Symbol;Acc:HGNC:7154]",0,0,1,0,1,1,"no","no"]
[40654,0,"chr12","-",45930950,45933172,"ENST00000546534",2,705,"MSTRG.3310","SCAF11","GO:0003723(RNA binding);GO:0006397(mRNA processing);GO:0008380(RNA splicing);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0005730(nucleolus);GO:0005654(nucleoplasm);GO:0016604(nuclear body);GO:0005515(protein binding);GO:0000375(RNA splicing, via transesterification reactions);GO:0000245(spliceosomal complex assembly)","NA","NA","NA","SR-related CTD associated factor 11 [Source:HGNC Symbol;Acc:HGNC:10784]",{"v":0.218732,"d":"0.22"},{"v":0.30005,"d":"0.30"},{"v":0.728985169138477,"d":"0.73"},{"v":-0.45603863099087,"d":"-0.46"},1,1,"down","no"]
[40283,0,"chr12","+",32733453,32737306,"ENST00000548151",2,557,"ENSG00000087470","DNM1L","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0043231(intracellular membrane-bounded organelle);GO:0005525(GTP binding);GO:0000166(nucleotide binding);GO:0005829(cytosol);GO:0016787(hydrolase activity);GO:0003924(GTPase activity);GO:0005794(Golgi apparatus);GO:0005739(mitochondrion);GO:0042803(protein homodimerization activity);GO:0043547(positive regulation of GTPase activity);GO:0005515(protein binding);GO:0048471(perinuclear region of cytoplasm);GO:0030054(cell junction);GO:0045202(synapse);GO:0005741(mitochondrial outer membrane);GO:0031410(cytoplasmic vesicle);GO:0016559(peroxisome fission);GO:0005905(clathrin-coated pit);GO:0005777(peroxisome);GO:0008289(lipid binding);GO:0005783(endoplasmic reticulum);GO:0006897(endocytosis);GO:0008017(microtubule binding);GO:0012505(endomembrane system);GO:0043234(protein complex);GO:0043065(positive regulation of apoptotic process);GO:0031625(ubiquitin protein ligase binding);GO:0000266(mitochondrial fission);GO:0001836(release of cytochrome c from mitochondria);GO:1903146(regulation of mitophagy);GO:0030742(GTP-dependent protein binding);GO:0051259(protein oligomerization);GO:0005874(microtubule);GO:0099073(mitochondrion-derived vesicle);GO:0005096(GTPase activator activity);GO:0017137(Rab GTPase binding);GO:0003374(dynamin family protein polymerization involved in mitochondrial fission);GO:0007005(mitochondrion organization);GO:0010821(regulation of mitochondrion organization);GO:0012501(programmed cell death);GO:0032459(regulation of protein oligomerization);GO:0043653(mitochondrial fragmentation involved in apoptotic process);GO:0048312(intracellular distribution of mitochondria);GO:0050714(positive regulation of protein secretion);GO:0051289(protein homotetramerization);GO:0061025(membrane fusion);GO:0070266(necroptotic process);GO:0070584(mitochondrion morphogenesis);GO:0090141(positive regulation of mitochondrial fission);GO:0090149(mitochondrial membrane fission);GO:0090200(positive regulation of release of cytochrome c from mitochondria);GO:0097194(execution phase of apoptosis);GO:1900063(regulation of peroxisome organization);GO:2001244(positive regulation of intrinsic apoptotic signaling pathway);GO:0005789(endoplasmic reticulum membrane);GO:0030672(synaptic vesicle membrane);GO:0030276(clathrin binding);GO:0032403(protein complex binding);GO:0051433(BH2 domain binding);GO:0010637(negative regulation of mitochondrial fusion);GO:0036466(synaptic vesicle recycling via endosome);GO:0051260(protein homooligomerization);GO:0060047(heart contraction);GO:0061003(positive regulation of dendritic spine morphogenesis);GO:0070585(protein localization to mitochondrion);GO:0071396(cellular response to lipid);GO:0090650(cellular response to oxygen-glucose deprivation);GO:1900244(positive regulation of synaptic vesicle endocytosis);GO:1903578(regulation of ATP metabolic process);GO:1904579(cellular response to thapsigargin);GO:1905395(response to flavonoid);GO:1990910(response to hypobaric hypoxia);GO:2000302(positive regulation of synaptic vesicle exocytosis);GO:0000139(Golgi membrane);GO:0005903(brush border);GO:0015630(microtubule cytoskeleton);GO:0031966(mitochondrial membrane);GO:0099503(secretory vesicle)","04668(TNF signaling pathway);04217(Necroptosis);04621(NOD-like receptor signaling pathway)","NA","NA","dynamin 1 like [Source:HGNC Symbol;Acc:HGNC:2973]",{"v":0.184567,"d":"0.18"},0,"inf","inf",1,1,"up","no"]
[58210,0,"chr14","+",95663256,95692630,"ENST00000553913",8,3217,"ENSG00000259084","AL133467.3","NA","NA","NA","NA","NA",0,0,1,0,1,1,"no","no"]
[91916,0,"chr18","+",36923940,37222302,"ENST00000586135",9,1863,"MSTRG.7499","KIAA1328","GO:0005515(protein binding)","NA","NA","NA","KIAA1328 [Source:HGNC Symbol;Acc:HGNC:29248]",{"v":0.016308,"d":"0.02"},0,"inf","inf",1,1,"up","no"]
[46739,0,"chr12","-",111644339,111673311,"ENST00000547043",8,1543,"MSTRG.3724","BRAP","GO:0003676(nucleic acid binding);GO:0005737(cytoplasm);GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0005829(cytosol);GO:0016740(transferase activity);GO:0016567(protein ubiquitination);GO:0031965(nuclear membrane);GO:0005515(protein binding);GO:0042802(identical protein binding);GO:0061630(ubiquitin protein ligase activity);GO:0000165(MAPK cascade);GO:0004842(ubiquitin-protein transferase activity);GO:0009968(negative regulation of signal transduction);GO:0000151(ubiquitin ligase complex);GO:0008139(nuclear localization sequence binding);GO:0007265(Ras protein signal transduction)","04014(Ras signaling pathway)","NA","NA","BRCA1 associated protein [Source:HGNC Symbol;Acc:HGNC:1099]",{"v":4.342911,"d":"4.34"},{"v":0.361525,"d":"0.36"},{"v":12.0127543046816,"d":"12.01"},{"v":3.58649506742392,"d":"3.59"},1,1,"up","no"]
[89938,0,"chr17","+",82468499,82478827,"ENST00000579083",3,561,"MSTRG.7368","NARF","GO:0005634(nucleus);GO:0005730(nucleolus);GO:0055114(oxidation-reduction process);GO:0003954(NADH dehydrogenase activity);GO:0005521(lamin binding);GO:0005638(lamin filament);GO:0005652(nuclear lamina);GO:0031981(nuclear lumen)","NA","NA","NA","nuclear prelamin A recognition factor [Source:HGNC Symbol;Acc:HGNC:29916]",{"v":0.08636,"d":"0.09"},{"v":0.213676,"d":"0.21"},{"v":0.404163312679009,"d":"0.40"},{"v":-1.30698972571361,"d":"-1.31"},1,1,"down","no"]
[102043,0,"chr19","-",42199465,42217706,"ENST00000601135",5,723,"MSTRG.8194","DEDD2","GO:0005634(nucleus);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0042981(regulation of apoptotic process);GO:0003677(DNA binding);GO:0006915(apoptotic process);GO:0005730(nucleolus);GO:0005515(protein binding);GO:0008625(extrinsic apoptotic signaling pathway via death domain receptors);GO:0045892(negative regulation of transcription, DNA-templated);GO:0035556(intracellular signal transduction);GO:0006396(RNA processing);GO:2001238(positive regulation of extrinsic apoptotic signaling pathway);GO:0030159(receptor signaling complex scaffold activity);GO:0016075(rRNA catabolic process);GO:0019725(cellular homeostasis);GO:0030262(apoptotic nuclear changes)","NA","NA","NA","death effector domain containing 2 [Source:HGNC Symbol;Acc:HGNC:24450]",0,{"v":4.111436,"d":"4.11"},"-inf","-inf",1,1,"down","no"]
[115684,0,"chr2","-",160275399,160277372,"ENST00000464200",2,386,"MSTRG.9181","RBMS1","GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0005634(nucleus);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0006260(DNA replication);GO:0003690(double-stranded DNA binding);GO:0003697(single-stranded DNA binding);GO:0006396(RNA processing)","NA","NA","NA","RNA binding motif single stranded interacting protein 1 [Source:HGNC Symbol;Acc:HGNC:9907]",{"v":1.512115,"d":"1.51"},{"v":0.513289,"d":"0.51"},{"v":2.94593299291432,"d":"2.95"},{"v":1.55872461574728,"d":"1.56"},1,1,"up","no"]
[9796,0,"chr1","-",119747996,119768894,"ENST00000369406",10,2428,"ENSG00000134240","HMGCS2","GO:0016740(transferase activity);GO:0005739(mitochondrion);GO:0003824(catalytic activity);GO:0006629(lipid metabolic process);GO:0008152(metabolic process);GO:0004421(hydroxymethylglutaryl-CoA synthase activity);GO:0006694(steroid biosynthetic process);GO:0008202(steroid metabolic process);GO:0008299(isoprenoid biosynthetic process);GO:0016126(sterol biosynthetic process);GO:0008203(cholesterol metabolic process);GO:0005743(mitochondrial inner membrane);GO:0006695(cholesterol biosynthetic process);GO:0005759(mitochondrial matrix);GO:0019216(regulation of lipid metabolic process);GO:0046951(ketone body biosynthetic process)","00650(Butanoate metabolism);00072(Synthesis and degradation of ketone bodies);00280(Valine, leucine and isoleucine degradation);00900(Terpenoid backbone biosynthesis);03320(PPAR signaling pathway)","K01641","EC:2.3.3.10","3-hydroxy-3-methylglutaryl-CoA synthase 2 [Source:HGNC Symbol;Acc:HGNC:5008]",{"v":0.0059,"d":"0.01"},{"v":0.032778,"d":"0.03"},{"v":0.17999877966929,"d":"0.18"},{"v":-2.47394096928258,"d":"-2.47"},1,1,"down","no"]
[73321,0,"chr16","+",56632707,56633518,"ENST00000570233",2,232,"ENSG00000205364","MT1M","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0008270(zinc ion binding);GO:0048471(perinuclear region of cytoplasm);GO:0045926(negative regulation of growth);GO:0071294(cellular response to zinc ion)","04978(Mineral absorption)","NA","NA","metallothionein 1M [Source:HGNC Symbol;Acc:HGNC:14296]",{"v":0.179454,"d":"0.18"},{"v":0.133338,"d":"0.13"},{"v":1.34585789497368,"d":"1.35"},{"v":0.428526088224757,"d":"0.43"},1,1,"up","no"]
[122408,0,"chr20","-",21154023,21218265,"ENST00000616177",7,5370,"ENSG00000232712","KIZ-AS1","NA","NA","NA","NA","KIZ antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:51231]",0,{"v":0.042819,"d":"0.04"},"-inf","-inf",1,1,"down","no"]
[180411,0,"chr7","+",152445477,152447150,"ENST00000465400",1,1674,"ENSG00000020219","CCT8L1P","NA","NA","NA","NA","chaperonin containing TCP1 subunit 8 like 1, pseudogene [Source:HGNC Symbol;Acc:HGNC:32153]",{"v":0.029171,"d":"0.03"},{"v":0.130549,"d":"0.13"},{"v":0.223448666784119,"d":"0.22"},{"v":-2.16198465802948,"d":"-2.16"},1,1,"down","no"]
[151943,0,"chr4","+",159350228,159354045,"ENST00000505026",4,970,"ENSG00000109756","RAPGEF2","GO:0005096(GTPase activator activity);GO:0043547(positive regulation of GTPase activity);GO:0042127(regulation of cell proliferation);GO:0017034(Rap guanyl-nucleotide exchange factor activity);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0007264(small GTPase mediated signal transduction);GO:0007165(signal transduction);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0004871(signal transducer activity);GO:0007186(G-protein coupled receptor signaling pathway);GO:0030552(cAMP binding);GO:0007275(multicellular organism development);GO:0048471(perinuclear region of cytoplasm);GO:0030054(cell junction);GO:0045202(synapse);GO:0007399(nervous system development);GO:0030154(cell differentiation);GO:0007218(neuropeptide signaling pathway);GO:0005509(calcium ion binding);GO:0005085(guanyl-nucleotide exchange factor activity);GO:0005887(integral component of plasma membrane);GO:0005923(bicellular tight junction);GO:0005768(endosome);GO:2001224(positive regulation of neuron migration);GO:0008285(negative regulation of cell proliferation);GO:0000165(MAPK cascade);GO:0043234(protein complex);GO:0005770(late endosome);GO:0043005(neuron projection);GO:0016324(apical plasma membrane);GO:0070374(positive regulation of ERK1 and ERK2 cascade);GO:2000670(positive regulation of dendritic cell apoptotic process);GO:0032092(positive regulation of protein binding);GO:0019933(cAMP-mediated signaling);GO:0061028(establishment of endothelial barrier);GO:0071321(cellular response to cGMP);GO:0005088(Ras guanyl-nucleotide exchange factor activity);GO:0005911(cell-cell junction);GO:0035556(intracellular signal transduction);GO:0048167(regulation of synaptic plasticity);GO:0030165(PDZ domain binding);GO:0043950(positive regulation of cAMP-mediated signaling);GO:0031175(neuron projection development);GO:0030033(microvillus assembly);GO:0045860(positive regulation of protein kinase activity);GO:0030139(endocytic vesicle);GO:0071320(cellular response to cAMP);GO:0001568(blood vessel development);GO:0010976(positive regulation of neuron projection development);GO:0001764(neuron migration);GO:0043025(neuronal cell body);GO:0070300(phosphatidic acid binding);GO:0071880(adenylate cyclase-activating adrenergic receptor signaling pathway);GO:0072659(protein localization to plasma membrane);GO:0019992(diacylglycerol binding);GO:0032486(Rap protein signal transduction);GO:0038180(nerve growth factor signaling pathway);GO:1990090(cellular response to nerve growth factor stimulus);GO:2001214(positive regulation of vasculogenesis);GO:0090557(establishment of endothelial intestinal barrier);GO:1901888(regulation of cell junction assembly);GO:0050699(WW domain binding);GO:0050774(negative regulation of dendrite morphogenesis);GO:2000481(positive regulation of cAMP-dependent protein kinase activity);GO:0031547(brain-derived neurotrophic factor receptor signaling pathway);GO:0031697(beta-1 adrenergic receptor binding);GO:0021591(ventricular system development);GO:0021884(forebrain neuron development);GO:0048022(negative regulation of melanin biosynthetic process);GO:0005622(intracellular)","04015(Rap1 signaling pathway);04010(MAPK signaling pathway);04530(Tight junction)","NA","NA","Rap guanine nucleotide exchange factor 2 [Source:HGNC Symbol;Acc:HGNC:16854]",0,{"v":0.566958,"d":"0.57"},"-inf","-inf",1,1,"down","no"]
[188009,0,"chr8","-",143586032,143597381,"ENST00000525695",3,907,"MSTRG.14619","EEF1D","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0006412(translation);GO:0005829(cytosol);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0001650(fibrillar center);GO:0005783(endoplasmic reticulum);GO:0005515(protein binding);GO:0004871(signal transducer activity);GO:0003746(translation elongation factor activity);GO:0006414(translational elongation);GO:0005853(eukaryotic translation elongation factor 1 complex);GO:0007165(signal transduction);GO:0045296(cadherin binding);GO:0043123(positive regulation of I-kappaB kinase/NF-kappaB signaling);GO:0008135(translation factor activity, RNA binding);GO:0071479(cellular response to ionizing radiation)","05168(Herpes simplex infection)","NA","NA","eukaryotic translation elongation factor 1 delta [Source:HGNC Symbol;Acc:HGNC:3211]",{"v":0.637043,"d":"0.64"},{"v":0.050477,"d":"0.05"},{"v":12.6204608039305,"d":"12.62"},{"v":3.65769268249851,"d":"3.66"},1,1,"up","no"]
[109086,0,"chr2","-",40114731,40430271,"ENST00000407929",8,3434,"ENSG00000183023","SLC8A1","GO:0010881(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion);GO:0002027(regulation of heart rate);GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0055085(transmembrane transport);GO:0046872(metal ion binding);GO:0005654(nucleoplasm);GO:0005886(plasma membrane);GO:0006811(ion transport);GO:0015297(antiporter activity);GO:0006814(sodium ion transport);GO:0006816(calcium ion transport);GO:0070588(calcium ion transmembrane transport);GO:0007154(cell communication);GO:0005509(calcium ion binding);GO:0005516(calmodulin binding);GO:0060078(regulation of postsynaptic membrane potential);GO:0005515(protein binding);GO:0005432(calcium:sodium antiporter activity);GO:0030501(positive regulation of bone mineralization);GO:0044325(ion channel binding);GO:0006936(muscle contraction);GO:1903779(regulation of cardiac conduction);GO:0042383(sarcolemma);GO:0035725(sodium ion transmembrane transport);GO:0010649(regulation of cell communication by electrical coupling);GO:0060048(cardiac muscle contraction);GO:0071313(cellular response to caffeine);GO:0030018(Z disc);GO:0070509(calcium ion import);GO:0035994(response to muscle stretch);GO:0055074(calcium ion homeostasis);GO:0030506(ankyrin binding);GO:0005887(integral component of plasma membrane);GO:0086012(membrane depolarization during cardiac muscle cell action potential);GO:0030315(T-tubule);GO:0014704(intercalated disc);GO:0008092(cytoskeletal protein binding);GO:0006883(cellular sodium ion homeostasis);GO:0055119(relaxation of cardiac muscle);GO:0086064(cell communication by electrical coupling involved in cardiac conduction);GO:0010882(regulation of cardiac muscle contraction by calcium ion signaling);GO:0002026(regulation of the force of heart contraction);GO:0098735(positive regulation of the force of heart contraction);GO:0014829(vascular smooth muscle contraction);GO:0044557(relaxation of smooth muscle);GO:0051481(negative regulation of cytosolic calcium ion concentration);GO:0055013(cardiac muscle cell development);GO:0060401(cytosolic calcium ion transport);GO:0060402(calcium ion transport into cytosol);GO:0097369(sodium ion import);GO:0099580(ion antiporter activity involved in regulation of postsynaptic membrane potential);GO:0001666(response to hypoxia);GO:0002028(regulation of sodium ion transport);GO:0006874(cellular calcium ion homeostasis);GO:0007204(positive regulation of cytosolic calcium ion concentration);GO:0007584(response to nutrient);GO:0009749(response to glucose);GO:0010763(positive regulation of fibroblast migration);GO:0021537(telencephalon development);GO:0033198(response to ATP);GO:0035902(response to immobilization stress);GO:0042493(response to drug);GO:0042542(response to hydrogen peroxide);GO:0051924(regulation of calcium ion transport);GO:0071320(cellular response to cAMP);GO:0071436(sodium ion export);GO:0071456(cellular response to hypoxia);GO:0005739(mitochondrion);GO:0005874(microtubule);GO:0042995(cell projection);GO:0043197(dendritic spine);GO:0043198(dendritic shaft);GO:0045211(postsynaptic membrane)","04371(Apelin signaling pathway);04020(Calcium signaling pathway);04022(cGMP - PKG signaling pathway);04260(Cardiac muscle contraction);04261(Adrenergic signaling in cardiomyocytes);04974(Protein digestion and absorption);04978(Mineral absorption);04961(Endocrine and other factor-regulated calcium reabsorption);04740(Olfactory transduction);05410(Hypertrophic cardiomyopathy (HCM));05412(Arrhythmogenic right ventricular cardiomyopathy (ARVC));05414(Dilated cardiomyopathy (DCM))","K05849","NA","solute carrier family 8 member A1 [Source:HGNC Symbol;Acc:HGNC:11068]",0,{"v":0.0126,"d":"0.01"},"-inf","-inf",1,1,"down","no"]
[100312,0,"chr19","-",35785697,35797871,"ENST00000637365",10,2000,"ENSG00000225872","LINC01529","NA","NA","NA","NA","long intergenic non-protein coding RNA 1529 [Source:HGNC Symbol;Acc:HGNC:51268]",{"v":0.025701,"d":"0.03"},0,"inf","inf",1,1,"up","no"]
[97449,0,"chr19","+",13919694,13923399,"ENST00000589679",4,610,"ENSG00000132024","CC2D1A","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005829(cytosol);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0001650(fibrillar center);GO:0005886(plasma membrane);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0004871(signal transducer activity);GO:0007165(signal transduction);GO:0005815(microtubule organizing center);GO:0045296(cadherin binding);GO:0070062(extracellular exosome);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0000981(RNA polymerase II transcription factor activity, sequence-specific DNA binding);GO:0043123(positive regulation of I-kappaB kinase/NF-kappaB signaling);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:0001078(transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding)","NA","NA","NA","coiled-coil and C2 domain containing 1A [Source:HGNC Symbol;Acc:HGNC:30237]",{"v":0.19444,"d":"0.19"},{"v":0.01041,"d":"0.01"},{"v":18.6781940441883,"d":"18.68"},{"v":4.22328306548916,"d":"4.22"},1,1,"up","no"]
[117114,0,"chr2","+",183124419,183161680,"ENST00000479162",7,2828,"ENSG00000163002","NUP35","GO:0003676(nucleic acid binding);GO:0006810(transport);GO:0051028(mRNA transport);GO:0005634(nucleus);GO:0016020(membrane);GO:0015031(protein transport);GO:0005654(nucleoplasm);GO:0031965(nuclear membrane);GO:0005886(plasma membrane);GO:0006913(nucleocytoplasmic transport);GO:0005515(protein binding);GO:0005643(nuclear pore);GO:0006355(regulation of transcription, DNA-templated);GO:0075733(intracellular transport of virus);GO:0043657(host cell);GO:0006607(NLS-bearing protein import into nucleus);GO:0003697(single-stranded DNA binding);GO:0016032(viral process);GO:0006406(mRNA export from nucleus);GO:0016925(protein sumoylation);GO:0060964(regulation of gene silencing by miRNA);GO:0006110(regulation of glycolytic process);GO:0006409(tRNA export from nucleus);GO:0007077(mitotic nuclear envelope disassembly);GO:0019083(viral transcription);GO:1900034(regulation of cellular response to heat);GO:0005635(nuclear envelope);GO:0044613(nuclear pore central transport channel);GO:0044615(nuclear pore nuclear basket);GO:0005487(nucleocytoplasmic transporter activity);GO:0005543(phospholipid binding);GO:0006999(nuclear pore organization);GO:0005652(nuclear lamina)","03013(RNA transport)","NA","NA","nucleoporin 35 [Source:HGNC Symbol;Acc:HGNC:29797]",0,{"v":0.020393,"d":"0.02"},"-inf","-inf",1,1,"down","no"]
[103290,0,"chr19","-",47489722,47515026,"ENST00000593761",10,891,"MSTRG.8274","NAPA","GO:0006810(transport);GO:0016020(membrane);GO:0006886(intracellular protein transport);GO:0015031(protein transport);GO:0005886(plasma membrane);GO:0000149(SNARE binding);GO:0019905(syntaxin binding);GO:0032403(protein complex binding);GO:0007420(brain development);GO:0010807(regulation of synaptic vesicle priming);GO:0030182(neuron differentiation);GO:0032781(positive regulation of ATPase activity);GO:0035249(synaptic transmission, glutamatergic);GO:0035494(SNARE complex disassembly);GO:0043241(protein complex disassembly);GO:0045176(apical protein localization);GO:0043195(terminal bouton);GO:0043209(myelin sheath);GO:0070044(synaptobrevin 2-SNAP-25-syntaxin-1a complex);GO:0005515(protein binding);GO:0016192(vesicle-mediated transport);GO:0000139(Golgi membrane);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0006890(retrograde vesicle-mediated transport, Golgi to ER);GO:0031201(SNARE complex);GO:0061025(membrane fusion);GO:0006888(ER to Golgi vesicle-mediated transport);GO:0048208(COPII vesicle coating);GO:0006891(intra-Golgi vesicle-mediated transport);GO:0005483(soluble NSF attachment protein activity);GO:0005774(vacuolar membrane);GO:0005622(intracellular)","04721(Synaptic vesicle cycle)","NA","NA","NSF attachment protein alpha [Source:HGNC Symbol;Acc:HGNC:7641]",{"v":0.210704,"d":"0.21"},{"v":0.114557,"d":"0.11"},{"v":1.83929397592465,"d":"1.84"},{"v":0.879152085357945,"d":"0.88"},1,1,"up","no"]
[158167,0,"chr5","+",132257703,132271873,"ENST00000474421",2,1084,"ENSG00000131435","PDLIM4","GO:0046872(metal ion binding);GO:0005515(protein binding)","NA","NA","NA","PDZ and LIM domain 4 [Source:HGNC Symbol;Acc:HGNC:16501]",0,{"v":0.105221,"d":"0.11"},"-inf","-inf",1,1,"down","no"]
[118654,0,"chr2","-",210290150,210303629,"ENST00000341685",7,870,"ENSG00000168530","MYL1","GO:0005509(calcium ion binding);GO:0016459(myosin complex);GO:0005829(cytosol);GO:0008307(structural constituent of muscle);GO:0030049(muscle filament sliding);GO:0006936(muscle contraction);GO:0005859(muscle myosin complex);GO:0030016(myofibril);GO:0030017(sarcomere);GO:0060048(cardiac muscle contraction);GO:0043292(contractile fiber)","NA","NA","NA","myosin light chain 1 [Source:HGNC Symbol;Acc:HGNC:7582]",{"v":0.020551,"d":"0.02"},0,"inf","inf",1,1,"up","no"]
[164869,0,"chr6","+",32033944,32034331,"ENST00000473957",2,303,"MSTRG.12894","C4B","GO:0005615(extracellular space);GO:0005576(extracellular region);GO:0010951(negative regulation of endopeptidase activity);GO:0042995(cell projection);GO:0006508(proteolysis);GO:0006954(inflammatory response);GO:0030054(cell junction);GO:0045202(synapse);GO:0002376(immune system process);GO:0045087(innate immune response);GO:0030425(dendrite);GO:0004252(serine-type endopeptidase activity);GO:0006956(complement activation);GO:0030449(regulation of complement activation);GO:0005886(plasma membrane);GO:0004866(endopeptidase inhibitor activity);GO:0030424(axon);GO:0070062(extracellular exosome);GO:0072562(blood microparticle);GO:0006958(complement activation, classical pathway);GO:2000427(positive regulation of apoptotic cell clearance);GO:0008228(opsonization);GO:0044216(other organism cell);GO:0001848(complement binding);GO:0030246(carbohydrate binding);GO:0032490(detection of molecule of bacterial origin)","04610(Complement and coagulation cascades);05322(Systemic lupus erythematosus);05133(Pertussis);05150(Staphylococcus aureus infection)","NA","NA","complement C4B (Chido blood group) [Source:HGNC Symbol;Acc:HGNC:1324]",0,0,1,0,1,1,"no","no"]
[71864,0,"chr16","-",30235520,30245877,"ENST00000564219",4,519,"ENSG00000198064","NPIPB13","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005654(nucleoplasm)","NA","NA","NA","nuclear pore complex interacting protein family, member B13 [Source:HGNC Symbol;Acc:HGNC:41989]",{"v":0.680211,"d":"0.68"},{"v":0.484102,"d":"0.48"},{"v":1.405098512297,"d":"1.41"},{"v":0.490671282204247,"d":"0.49"},1,1,"up","no"]
[107224,0,"chr2","+",9474858,9488314,"ENST00000481688",6,1011,"MSTRG.8500","IAH1","GO:0016787(hydrolase activity);GO:0006629(lipid metabolic process);GO:0016042(lipid catabolic process);GO:0070062(extracellular exosome)","NA","NA","NA","isoamyl acetate-hydrolyzing esterase 1 homolog [Source:HGNC Symbol;Acc:HGNC:27696]",{"v":0.000343,"d":"0.00"},{"v":0.018954,"d":"0.02"},{"v":0.0180964440223699,"d":"0.02"},{"v":-5.78814995629522,"d":"-5.79"},1,1,"down","no"]
[134534,0,"chr3","-",33498584,33535448,"ENST00000476251",7,1097,"MSTRG.10796","CLASP2","GO:0005794(Golgi apparatus);GO:0005829(cytosol);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0051301(cell division);GO:0005694(chromosome);GO:0005886(plasma membrane);GO:0005856(cytoskeleton);GO:0042995(cell projection);GO:0005515(protein binding);GO:0007049(cell cycle);GO:0005874(microtubule);GO:0005925(focal adhesion);GO:0008017(microtubule binding);GO:0005815(microtubule organizing center);GO:0005819(spindle);GO:0000775(chromosome, centromeric region);GO:0000776(kinetochore);GO:0000777(condensed chromosome kinetochore);GO:0031252(cell leading edge);GO:0005802(trans-Golgi network);GO:0032587(ruffle membrane);GO:0010717(regulation of epithelial to mesenchymal transition);GO:0007052(mitotic spindle organization);GO:0007062(sister chromatid cohesion);GO:0045921(positive regulation of exocytosis);GO:0000226(microtubule cytoskeleton organization);GO:0002162(dystroglycan binding);GO:0010458(exit from mitosis);GO:0051895(negative regulation of focal adhesion assembly);GO:0090002(establishment of protein localization to plasma membrane);GO:0007030(Golgi organization);GO:0005881(cytoplasmic microtubule);GO:0010634(positive regulation of epithelial cell migration);GO:0005828(kinetochore microtubule);GO:0032886(regulation of microtubule-based process);GO:0005938(cell cortex);GO:0072686(mitotic spindle);GO:0051010(microtubule plus-end binding);GO:0006903(vesicle targeting);GO:0007020(microtubule nucleation);GO:0007026(negative regulation of microtubule depolymerization);GO:0007163(establishment or maintenance of cell polarity);GO:0010470(regulation of gastrulation);GO:0031023(microtubule organizing center organization);GO:0031110(regulation of microtubule polymerization or depolymerization);GO:0034453(microtubule anchoring);GO:0051497(negative regulation of stress fiber assembly);GO:0090091(positive regulation of extracellular matrix disassembly);GO:1903690(negative regulation of wound healing, spreading of epidermal cells);GO:1904261(positive regulation of basement membrane assembly involved in embryonic body morphogenesis);GO:0045180(basal cortex)","NA","NA","NA","cytoplasmic linker associated protein 2 [Source:HGNC Symbol;Acc:HGNC:17078]",0,0,1,0,1,1,"no","no"]
[68730,0,"chr16","-",3096450,3099292,"ENST00000573931",2,135,"ENSG00000130182","ZSCAN10","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0043565(sequence-specific DNA binding);GO:0045892(negative regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0005654(nucleoplasm);GO:0035019(somatic stem cell population maintenance)","NA","NA","NA","zinc finger and SCAN domain containing 10 [Source:HGNC Symbol;Acc:HGNC:12997]",{"v":0.080092,"d":"0.08"},0,"inf","inf",1,1,"up","no"]
[39580,0,"chr12","-",22200999,22334714,"ENST00000261197",4,1996,"ENSG00000111728","ST8SIA1","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016740(transferase activity);GO:0008373(sialyltransferase activity);GO:0016757(transferase activity, transferring glycosyl groups);GO:0006486(protein glycosylation);GO:0097503(sialylation);GO:0005794(Golgi apparatus);GO:0006629(lipid metabolic process);GO:0000139(Golgi membrane);GO:0006665(sphingolipid metabolic process);GO:0005975(carbohydrate metabolic process);GO:0003828(alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity);GO:0006688(glycosphingolipid biosynthetic process);GO:0008284(positive regulation of cell proliferation);GO:0034605(cellular response to heat)","00601(Glycosphingolipid biosynthesis - lacto and neolacto series);00603(Glycosphingolipid biosynthesis - globo and isoglobo series);00604(Glycosphingolipid biosynthesis - ganglio series)","NA","NA","ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:10869]",0,0,1,0,1,1,"no","no"]
[69960,0,"chr16","-",15133488,15135153,"ENST00000540502",4,764,"MSTRG.5691","PKD1P6","NA","NA","NA","NA","polycystin 1, transient receptor potential channel interacting pseudogene 6 [Source:HGNC Symbol;Acc:HGNC:30070]",{"v":0.073941,"d":"0.07"},{"v":0.108845,"d":"0.11"},{"v":0.679323809086316,"d":"0.68"},{"v":-0.55782867593028,"d":"-0.56"},1,1,"down","no"]
[104898,0,"chr19","+",52297179,52321647,"ENST00000598016",6,559,"ENSG00000198464","ZNF480","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0005622(intracellular)","NA","NA","NA","zinc finger protein 480 [Source:HGNC Symbol;Acc:HGNC:23305]",{"v":0.131431,"d":"0.13"},0,"inf","inf",1,1,"up","no"]
[42226,0,"chr12","+",53461136,53480807,"ENST00000547859",8,1919,"MSTRG.3414","PCBP2","GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0003677(DNA binding);GO:0030529(intracellular ribonucleoprotein complex);GO:0005515(protein binding);GO:0002376(immune system process);GO:0045087(innate immune response);GO:0005925(focal adhesion);GO:0051607(defense response to virus);GO:0070062(extracellular exosome);GO:0031625(ubiquitin protein ligase binding);GO:0019899(enzyme binding);GO:0075522(IRES-dependent viral translational initiation);GO:0043161(proteasome-mediated ubiquitin-dependent protein catabolic process);GO:0032480(negative regulation of type I interferon production);GO:0000398(mRNA splicing, via spliceosome);GO:0016070(RNA metabolic process);GO:0050687(negative regulation of defense response to virus);GO:0016071(mRNA metabolic process);GO:0039694(viral RNA genome replication)","04216(Ferroptosis)","NA","NA","poly(rC) binding protein 2 [Source:HGNC Symbol;Acc:HGNC:8648]",{"v":0.234203,"d":"0.23"},{"v":0.012559,"d":"0.01"},{"v":18.6482203997134,"d":"18.65"},{"v":4.22096605550144,"d":"4.22"},1,1,"up","no"]
[51505,0,"chr13","-",99962964,99971909,"ENST00000267294",2,4639,"ENSG00000139800","ZIC5","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0003677(DNA binding);GO:0007275(multicellular organism development);GO:0007399(nervous system development);GO:0030154(cell differentiation)","NA","NA","NA","Zic family member 5 [Source:HGNC Symbol;Acc:HGNC:20322]",0,{"v":9.835E-3,"d":"0.01"},"-inf","-inf",1,1,"down","no"]
[48146,0,"chr12","-",123936417,123946773,"ENST00000545135",3,4883,"MSTRG.3851","CCDC92","GO:0005737(cytoplasm);GO:0043231(intracellular membrane-bounded organelle);GO:0005654(nucleoplasm);GO:0005813(centrosome);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0005814(centriole)","NA","NA","NA","coiled-coil domain containing 92 [Source:HGNC Symbol;Acc:HGNC:29563]",{"v":1e-06,"d":"0.00"},{"v":0.233377,"d":"0.23"},{"v":4.28491239496608e-06,"d":"0.00"},{"v":-17.832302860585,"d":"-17.83"},1,1,"down","no"]
[189394,0,"chr9","+",21802636,22032986,"ENST00000404796",6,935,"ENSG00000264545","AL359922.1","GO:0009116(nucleoside metabolic process);GO:0003824(catalytic activity);GO:0016763(transferase activity, transferring pentosyl groups);GO:0017061(S-methyl-5-thioadenosine phosphorylase activity)","NA","NA","NA","NA",{"v":0.000277,"d":"0.00"},0,"inf","inf",1,1,"up","no"]
[96814,0,"chr19","-",11496036,11505184,"ENST00000593191",3,709,"MSTRG.7825","ZNF653","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding)","NA","NA","NA","zinc finger protein 653 [Source:HGNC Symbol;Acc:HGNC:25196]",0,{"v":0.06451,"d":"0.06"},"-inf","-inf",1,1,"down","no"]
[191482,0,"chr9","+",87498535,87638027,"ENST00000496522",4,579,"ENSG00000196730","DAPK1","GO:0005737(cytoplasm);GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0007165(signal transduction);GO:0005525(GTP binding);GO:0005886(plasma membrane);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0006915(apoptotic process);GO:0042802(identical protein binding);GO:0005516(calmodulin binding);GO:0006417(regulation of translation);GO:0071346(cellular response to interferon-gamma);GO:0017148(negative regulation of translation);GO:0042981(regulation of apoptotic process);GO:0097190(apoptotic signaling pathway);GO:0046777(protein autophosphorylation);GO:0010506(regulation of autophagy);GO:0035556(intracellular signal transduction);GO:0043280(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process);GO:0015629(actin cytoskeleton);GO:0017075(syntaxin-1 binding);GO:2000310(regulation of NMDA receptor activity);GO:0004683(calmodulin-dependent protein kinase activity);GO:0010508(positive regulation of autophagy);GO:0071447(cellular response to hydroperoxide);GO:0008625(extrinsic apoptotic signaling pathway via death domain receptors);GO:0043066(negative regulation of apoptotic process);GO:1902042(negative regulation of extrinsic apoptotic signaling pathway via death domain receptors)","04140(Autophagy - animal);05200(Pathways in cancer);05219(Bladder cancer)","NA","NA","death associated protein kinase 1 [Source:HGNC Symbol;Acc:HGNC:2674]",0,0,1,0,1,1,"no","no"]
[5438,0,"chr1","+",45014539,45015392,"ENST00000466193",2,524,"MSTRG.517","UROD","GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0016829(lyase activity);GO:0005515(protein binding);GO:0016831(carboxy-lyase activity);GO:0006783(heme biosynthetic process);GO:0006779(porphyrin-containing compound biosynthetic process);GO:0004853(uroporphyrinogen decarboxylase activity);GO:0006782(protoporphyrinogen IX biosynthetic process);GO:0042168(heme metabolic process)","00860(Porphyrin and chlorophyll metabolism)","NA","NA","uroporphyrinogen decarboxylase [Source:HGNC Symbol;Acc:HGNC:12591]",{"v":0.181386,"d":"0.18"},{"v":0.203869,"d":"0.20"},{"v":0.889718397598458,"d":"0.89"},{"v":-0.168579310128071,"d":"-0.17"},1,1,"down","no"]
[71879,0,"chr16","-",30359184,30360043,"ENST00000566671",3,561,"MSTRG.5837","TBC1D10B","GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0005096(GTPase activator activity);GO:0017137(Rab GTPase binding);GO:0006886(intracellular protein transport);GO:0031338(regulation of vesicle fusion);GO:0090630(activation of GTPase activity);GO:0005622(intracellular);GO:0012505(endomembrane system);GO:0005515(protein binding);GO:0042147(retrograde transport, endosome to Golgi);GO:0043087(regulation of GTPase activity)","NA","NA","NA","TBC1 domain family member 10B [Source:HGNC Symbol;Acc:HGNC:24510]",0,{"v":0.02385,"d":"0.02"},"-inf","-inf",1,1,"down","no"]
[5846,0,"chr1","+",48222685,48247601,"ENST00000425816",13,1950,"ENSG00000117834","SLC5A9","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0006810(transport);GO:0005215(transporter activity);GO:0055085(transmembrane transport);GO:0006811(ion transport);GO:0006814(sodium ion transport);GO:0005886(plasma membrane);GO:0005887(integral component of plasma membrane);GO:0005412(glucose:sodium symporter activity);GO:0008645(hexose transport);GO:1904659(glucose transmembrane transport);GO:0070062(extracellular exosome);GO:0005362(low-affinity glucose:sodium symporter activity)","NA","NA","NA","solute carrier family 5 member 9 [Source:HGNC Symbol;Acc:HGNC:22146]",{"v":0.158393,"d":"0.16"},0,"inf","inf",1,1,"up","no"]
[110713,0,"chr2","-",70046568,70059961,"ENST00000603347",3,651,"MSTRG.8891","PCBP1-AS1","NA","NA","NA","NA","PCBP1 antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:42948]",0,0,1,0,1,1,"no","no"]
[144940,0,"chr4","+",499243,507538,"ENST00000511448",5,903,"ENSG00000174227","PIGG","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0003824(catalytic activity);GO:0008152(metabolic process);GO:0016740(transferase activity);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0006506(GPI anchor biosynthetic process);GO:0030176(integral component of endoplasmic reticulum membrane);GO:0016254(preassembly of GPI anchor in ER membrane);GO:0016780(phosphotransferase activity, for other substituted phosphate groups);GO:0051267(CP2 mannose-ethanolamine phosphotransferase activity)","00563(Glycosylphosphatidylinositol(GPI)-anchor biosynthesis)","NA","NA","phosphatidylinositol glycan anchor biosynthesis class G [Source:HGNC Symbol;Acc:HGNC:25985]",0,0,1,0,1,1,"no","no"]
[71120,0,"chr16","+",27573907,27677818,"ENST00000568258",7,746,"ENSG00000047578","KIAA0556","GO:0005737(cytoplasm);GO:0005856(cytoskeleton);GO:0042995(cell projection);GO:0005615(extracellular space)","NA","NA","NA","KIAA0556 [Source:HGNC Symbol;Acc:HGNC:29068]",0,0,1,0,1,1,"no","no"]
[163243,0,"chr6","-",24649979,24666591,"ENST00000341060",6,2120,"MSTRG.12708","TDP2","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0005654(nucleoplasm);GO:0016787(hydrolase activity);GO:0090305(nucleic acid phosphodiester bond hydrolysis);GO:0016235(aggresome);GO:0006281(DNA repair);GO:0006974(cellular response to DNA damage stimulus);GO:0016604(nuclear body);GO:0000287(magnesium ion binding);GO:0004518(nuclease activity);GO:0005730(nucleolus);GO:1903507(negative regulation of nucleic acid-templated transcription);GO:0005515(protein binding);GO:0048666(neuron development);GO:0007166(cell surface receptor signaling pathway);GO:0003714(transcription corepressor activity);GO:0016605(PML body);GO:0003697(single-stranded DNA binding);GO:0006302(double-strand break repair);GO:0030145(manganese ion binding);GO:0036317(tyrosyl-RNA phosphodiesterase activity);GO:0070260(5'-tyrosyl-DNA phosphodiesterase activity)","NA","NA","NA","tyrosyl-DNA phosphodiesterase 2 [Source:HGNC Symbol;Acc:HGNC:17768]",{"v":0.527845,"d":"0.53"},0,"inf","inf",1,1,"up","no"]
[30113,0,"chr11","+",61950356,61956866,"ENST00000533521",4,1128,"MSTRG.2448","BEST1","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0007601(visual perception);GO:0006811(ion transport);GO:0005886(plasma membrane);GO:0005254(chloride channel activity);GO:0006821(chloride transport);GO:0015701(bicarbonate transport);GO:0034707(chloride channel complex);GO:1902476(chloride transmembrane transport);GO:0050896(response to stimulus);GO:0042802(identical protein binding);GO:0005229(intracellular calcium activated chloride channel activity);GO:0034220(ion transmembrane transport);GO:0016323(basolateral plasma membrane);GO:0005829(cytosol);GO:0015106(bicarbonate transmembrane transporter activity);GO:0030321(transepithelial chloride transport);GO:0050908(detection of light stimulus involved in visual perception);GO:0051924(regulation of calcium ion transport)","NA","NA","NA","bestrophin 1 [Source:HGNC Symbol;Acc:HGNC:12703]",{"v":0.005235,"d":"0.01"},0,"inf","inf",1,1,"up","no"]
[43822,0,"chr12","-",62689750,62788484,"ENST00000551519",5,584,"ENSG00000111110","PPM1H","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005654(nucleoplasm);GO:0016787(hydrolase activity);GO:0003824(catalytic activity);GO:0006470(protein dephosphorylation);GO:0004721(phosphoprotein phosphatase activity);GO:0004722(protein serine/threonine phosphatase activity)","NA","NA","NA","protein phosphatase, Mg2+/Mn2+ dependent 1H [Source:HGNC Symbol;Acc:HGNC:18583]",{"v":0.33728,"d":"0.34"},0,"inf","inf",1,1,"up","no"]
[22721,0,"chr10","+",98163287,98244892,"ENST00000613938",6,1397,"ENSG00000166024","R3HCC1L","GO:0005515(protein binding);GO:0035145(exon-exon junction complex)","NA","NA","NA","R3H domain and coiled-coil containing 1 like [Source:HGNC Symbol;Acc:HGNC:23512]",0,{"v":1.908157,"d":"1.91"},"-inf","-inf",1,1,"down","no"]
[2967,0,"chr1","-",25834006,25859412,"ENST00000374298",3,2116,"MSTRG.275","AUNIP","GO:0005737(cytoplasm);GO:0005813(centrosome);GO:0005856(cytoskeleton);GO:0000922(spindle pole);GO:0005815(microtubule organizing center);GO:0005515(protein binding);GO:0007051(spindle organization)","NA","NA","NA","aurora kinase A and ninein interacting protein [Source:HGNC Symbol;Acc:HGNC:28363]",{"v":0.266079,"d":"0.27"},{"v":0.091101,"d":"0.09"},{"v":2.92070339513287,"d":"2.92"},{"v":1.54631585625067,"d":"1.55"},1,1,"up","no"]
[96778,0,"chr19","-",11420605,11435782,"ENST00000586836",13,1867,"MSTRG.7841","CCDC151","GO:0005737(cytoplasm);GO:0005856(cytoskeleton);GO:0042995(cell projection);GO:0005515(protein binding);GO:0003341(cilium movement);GO:0005929(cilium);GO:0030030(cell projection organization);GO:0005814(centriole);GO:0007368(determination of left/right symmetry);GO:0036158(outer dynein arm assembly);GO:0070286(axonemal dynein complex assembly);GO:1902017(regulation of cilium assembly);GO:0005930(axoneme);GO:0036064(ciliary basal body)","NA","NA","NA","coiled-coil domain containing 151 [Source:HGNC Symbol;Acc:HGNC:28303]",{"v":0.008535,"d":"0.01"},0,"inf","inf",1,1,"up","no"]
[137959,0,"chr3","-",69197715,69320944,"ENST00000470070",12,1830,"ENSG00000114541","FRMD4B","GO:0005737(cytoplasm);GO:0005856(cytoskeleton);GO:0005615(extracellular space);GO:0090162(establishment of epithelial cell polarity);GO:0001726(ruffle)","NA","NA","NA","FERM domain containing 4B [Source:HGNC Symbol;Acc:HGNC:24886]",0,0,1,0,1,1,"no","no"]
[128518,0,"chr22","+",19432939,19436010,"ENST00000471259",3,942,"MSTRG.10130","MRPL40","GO:0003723(RNA binding);GO:0030529(intracellular ribonucleoprotein complex);GO:0005840(ribosome);GO:0005739(mitochondrion);GO:0005515(protein binding);GO:0005634(nucleus);GO:0009653(anatomical structure morphogenesis);GO:0005743(mitochondrial inner membrane);GO:0070125(mitochondrial translational elongation);GO:0070126(mitochondrial translational termination);GO:0005761(mitochondrial ribosome);GO:0005762(mitochondrial large ribosomal subunit)","NA","NA","NA","mitochondrial ribosomal protein L40 [Source:HGNC Symbol;Acc:HGNC:14491]",{"v":0.047684,"d":"0.05"},{"v":0.470289,"d":"0.47"},{"v":0.10139297325687,"d":"0.10"},{"v":-3.30197042083736,"d":"-3.30"},1,1,"down","no"]
[21250,0,"chr10","+",73496287,73520070,"ENST00000600206",4,842,"ENSG00000221817","PPP3CB-AS1","NA","NA","NA","NA","PPP3CB antisense RNA 1 (head to head) [Source:HGNC Symbol;Acc:HGNC:50750]",0,0,1,0,1,1,"no","no"]
[8471,0,"chr1","-",100990063,101021720,"ENST00000492067",4,767,"ENSG00000117543","DPH5","GO:0008168(methyltransferase activity);GO:0016740(transferase activity);GO:0032259(methylation);GO:0008152(metabolic process);GO:0005575(cellular_component);GO:0005829(cytosol);GO:0017183(peptidyl-diphthamide biosynthetic process from peptidyl-histidine);GO:0004164(diphthine synthase activity)","NA","NA","NA","diphthamide biosynthesis 5 [Source:HGNC Symbol;Acc:HGNC:24270]",{"v":0.75442,"d":"0.75"},{"v":0.665786,"d":"0.67"},{"v":1.13312686058283,"d":"1.13"},{"v":0.180309388862025,"d":"0.18"},1,1,"up","no"]
[89657,0,"chr17","-",82035879,82037681,"ENST00000579334",7,1251,"MSTRG.7343","DCXR","GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0005634(nucleus);GO:0016020(membrane);GO:0005975(carbohydrate metabolic process);GO:0005886(plasma membrane);GO:0042802(identical protein binding);GO:0070062(extracellular exosome);GO:0006006(glucose metabolic process);GO:0051289(protein homotetramerization);GO:0005881(cytoplasmic microtubule);GO:0005997(xylulose metabolic process);GO:0019640(glucuronate catabolic process to xylulose 5-phosphate);GO:0042732(D-xylose metabolic process);GO:0016655(oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor);GO:0016614(oxidoreductase activity, acting on CH-OH group of donors);GO:0050038(L-xylulose reductase (NADP+) activity);GO:0006739(NADP metabolic process);GO:0005902(microvillus);GO:0005903(brush border)","00040(Pentose and glucuronate interconversions)","NA","NA","dicarbonyl and L-xylulose reductase [Source:HGNC Symbol;Acc:HGNC:18985]",0,0,1,0,1,1,"no","no"]
[131734,0,"chr22","-",41584020,41589847,"ENST00000414636",6,567,"MSTRG.10516","PMM1","GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0016853(isomerase activity);GO:0005515(protein binding);GO:0004615(phosphomannomutase activity);GO:0009298(GDP-mannose biosynthetic process);GO:1990830(cellular response to leukemia inhibitory factor);GO:0043025(neuronal cell body);GO:0005829(cytosol);GO:0006487(protein N-linked glycosylation);GO:0045047(protein targeting to ER);GO:0006013(mannose metabolic process)","00051(Fructose and mannose metabolism);00520(Amino sugar and nucleotide sugar metabolism)","NA","NA","phosphomannomutase 1 [Source:HGNC Symbol;Acc:HGNC:9114]",{"v":0.586397,"d":"0.59"},0,"inf","inf",1,1,"up","no"]
[132605,0,"chr22","-",50569084,50578455,"ENST00000395650",19,2662,"MSTRG.10612","CPT1B","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016740(transferase activity);GO:0016746(transferase activity, transferring acyl groups);GO:0006629(lipid metabolic process);GO:0006631(fatty acid metabolic process);GO:0005739(mitochondrion);GO:0005515(protein binding);GO:0005741(mitochondrial outer membrane);GO:0006853(carnitine shuttle);GO:0006635(fatty acid beta-oxidation);GO:0004095(carnitine O-palmitoyltransferase activity);GO:0015909(long-chain fatty acid transport);GO:0043231(intracellular membrane-bounded organelle)","00071(Fatty acid degradation);04152(AMPK signaling pathway);04922(Glucagon signaling pathway);04920(Adipocytokine signaling pathway);03320(PPAR signaling pathway);04931(Insulin resistance)","K19523","EC:2.3.1.21","carnitine palmitoyltransferase 1B [Source:HGNC Symbol;Acc:HGNC:2329]",0,0,1,0,1,1,"no","no"]
[9854,0,"chr1","+",120913379,120953449,"ENST00000613486",3,486,"MSTRG.841","LINC00623","NA","NA","NA","NA","long intergenic non-protein coding RNA 623 [Source:HGNC Symbol;Acc:HGNC:44252]",0,0,1,0,1,1,"no","no"]
[99060,0,"chr19","+",20077994,20127076,"ENST00000474284",4,1724,"MSTRG.8027","ZNF90","GO:0003676(nucleic acid binding);GO:0006355(regulation of transcription, DNA-templated);GO:0005622(intracellular);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0008270(zinc ion binding)","NA","NA","NA","zinc finger protein 90 [Source:HGNC Symbol;Acc:HGNC:13165]",0,0,1,0,1,1,"no","no"]
[95529,0,"chr19","+",6494320,6495025,"ENST00000596027",2,520,"ENSG00000268191","AC010503.1","NA","NA","NA","NA","NA",{"v":0.000209,"d":"0.00"},{"v":1.06E-4,"d":"0.00"},{"v":1.97169811320755,"d":"1.97"},{"v":0.979438677517684,"d":"0.98"},1,1,"up","no"]
[107285,0,"chr2","+",10122328,10131418,"ENST00000360566",10,3673,"ENSG00000171848","RRM2","GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0005829(cytosol);GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0005515(protein binding);GO:0006260(DNA replication);GO:0009263(deoxyribonucleotide biosynthetic process);GO:0004748(ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor);GO:0015949(nucleobase-containing small molecule interconversion);GO:0000083(regulation of transcription involved in G1/S transition of mitotic cell cycle);GO:0005971(ribonucleoside-diphosphate reductase complex)","00230(Purine metabolism);00240(Pyrimidine metabolism);00480(Glutathione metabolism);00983(Drug metabolism - other enzymes);04115(p53 signaling pathway)","NA","NA","ribonucleotide reductase regulatory subunit M2 [Source:HGNC Symbol;Acc:HGNC:10452]",{"v":1.134578,"d":"1.13"},{"v":0.109119,"d":"0.11"},{"v":10.3976209459398,"d":"10.40"},{"v":3.37818156151074,"d":"3.38"},1,1,"up","no"]
[88846,0,"chr17","-",78674048,78717025,"ENST00000585509",14,3315,"MSTRG.7289","CYTH1","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0043547(positive regulation of GTPase activity);GO:0005515(protein binding);GO:0005086(ARF guanyl-nucleotide exchange factor activity);GO:0032012(regulation of ARF protein signal transduction);GO:0005085(guanyl-nucleotide exchange factor activity);GO:0008289(lipid binding);GO:0005923(bicellular tight junction);GO:0031234(extrinsic component of cytoplasmic side of plasma membrane);GO:0016192(vesicle-mediated transport);GO:0000139(Golgi membrane);GO:0090162(establishment of epithelial cell polarity);GO:0030155(regulation of cell adhesion)","04072(Phospholipase D signaling pathway);04144(Endocytosis)","K18441","NA","cytohesin 1 [Source:HGNC Symbol;Acc:HGNC:9501]",{"v":0.021852,"d":"0.02"},{"v":2.9E-5,"d":"0.00"},{"v":753.51724137931,"d":"753.52"},{"v":9.55749671257042,"d":"9.56"},1,1,"up","no"]
[37745,0,"chr12","+",6232186,6236262,"ENST00000540891",6,642,"MSTRG.3019","CD9","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0007155(cell adhesion);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0005615(extracellular space);GO:0005925(focal adhesion);GO:0005887(integral component of plasma membrane);GO:0070062(extracellular exosome);GO:0007166(cell surface receptor signaling pathway);GO:0007338(single fertilization);GO:0007342(fusion of sperm to egg plasma membrane);GO:0002576(platelet degranulation);GO:0030666(endocytic vesicle membrane);GO:1903561(extracellular vesicle);GO:0006928(movement of cell or subcellular component);GO:0030168(platelet activation);GO:0030669(clathrin-coated endocytic vesicle membrane);GO:0031092(platelet alpha granule membrane);GO:0031623(receptor internalization);GO:0071404(cellular response to low-density lipoprotein particle stimulus);GO:0090331(negative regulation of platelet aggregation);GO:0005178(integrin binding);GO:0007420(brain development);GO:0008285(negative regulation of cell proliferation);GO:0009414(response to water deprivation);GO:0014003(oligodendrocyte development);GO:0030913(paranodal junction assembly);GO:0009897(external side of plasma membrane);GO:0009986(cell surface);GO:0016324(apical plasma membrane)","04640(Hematopoietic cell lineage)","NA","NA","CD9 molecule [Source:HGNC Symbol;Acc:HGNC:1709]",0,0,1,0,1,1,"no","no"]
[189755,0,"chr9","-",33944515,34048949,"ENST00000412543",12,1349,"MSTRG.14729","UBAP2","GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0045296(cadherin binding);GO:0010628(positive regulation of gene expression)","NA","NA","NA","ubiquitin associated protein 2 [Source:HGNC Symbol;Acc:HGNC:14185]",0,{"v":0.054907,"d":"0.05"},"-inf","-inf",1,1,"down","no"]
[51010,0,"chr13","-",77015165,77018744,"ENST00000470210",2,561,"MSTRG.4034","FBXL3","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016567(protein ubiquitination);GO:0005829(cytosol);GO:0016604(nuclear body);GO:0048511(rhythmic process);GO:0005515(protein binding);GO:0031648(protein destabilization);GO:0000209(protein polyubiquitination);GO:0043687(post-translational protein modification);GO:0004842(ubiquitin-protein transferase activity);GO:0000151(ubiquitin ligase complex);GO:0042752(regulation of circadian rhythm);GO:0043153(entrainment of circadian clock by photoperiod);GO:0019005(SCF ubiquitin ligase complex);GO:0031146(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process);GO:0043161(proteasome-mediated ubiquitin-dependent protein catabolic process)","04710(Circadian rhythm)","NA","NA","F-box and leucine rich repeat protein 3 [Source:HGNC Symbol;Acc:HGNC:13599]",0,0,1,0,1,1,"no","no"]
[55346,0,"chr14","-",57244279,57268440,"ENST00000556318",4,518,"MSTRG.4424","EXOC5","GO:0006810(transport);GO:0005737(cytoplasm);GO:0015031(protein transport);GO:0006887(exocytosis);GO:0000145(exocyst);GO:0005515(protein binding);GO:0030496(midbody);GO:0048278(vesicle docking);GO:0005829(cytosol);GO:0017160(Ral GTPase binding);GO:0006892(post-Golgi vesicle-mediated transport);GO:0047485(protein N-terminus binding);GO:0006893(Golgi to plasma membrane transport)","NA","NA","NA","exocyst complex component 5 [Source:HGNC Symbol;Acc:HGNC:10696]",{"v":0.005954,"d":"0.01"},{"v":2.33E-4,"d":"0.00"},{"v":25.5536480686695,"d":"25.55"},{"v":4.67545736158376,"d":"4.68"},1,1,"up","no"]
[88209,0,"chr17","-",75835419,75844360,"ENST00000586147",6,589,"MSTRG.7225","UNC13D","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005829(cytosol);GO:0005764(lysosome);GO:0005576(extracellular region);GO:0005783(endoplasmic reticulum);GO:0005515(protein binding);GO:0006887(exocytosis);GO:0005768(endosome);GO:0005770(late endosome);GO:0055037(recycling endosome);GO:0043312(neutrophil degranulation);GO:0045921(positive regulation of exocytosis);GO:0035578(azurophil granule lumen);GO:0017137(Rab GTPase binding);GO:1903307(positive regulation of regulated secretory pathway);GO:0033093(Weibel-Palade body);GO:0070382(exocytic vesicle);GO:0043304(regulation of mast cell degranulation);GO:0002432(granuloma formation);GO:0002467(germinal center formation);GO:0006909(phagocytosis);GO:0043320(natural killer cell degranulation);GO:0051607(defense response to virus);GO:1900026(positive regulation of substrate adhesion-dependent cell spreading)","NA","NA","NA","unc-13 homolog D [Source:HGNC Symbol;Acc:HGNC:23147]",{"v":0.137077,"d":"0.14"},{"v":0.355991,"d":"0.36"},{"v":0.38505748740839,"d":"0.39"},{"v":-1.37685424490414,"d":"-1.38"},1,1,"down","no"]
[185184,0,"chr8","-",85336945,85378113,"ENST00000522662",5,501,"MSTRG.14427","CA1","GO:0005737(cytoplasm);GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0016829(lyase activity);GO:0006730(one-carbon metabolic process);GO:0005515(protein binding);GO:0004089(carbonate dehydratase activity);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0035722(interleukin-12-mediated signaling pathway);GO:0015701(bicarbonate transport);GO:0004064(arylesterase activity);GO:0016836(hydro-lyase activity)","00910(Nitrogen metabolism)","NA","NA","carbonic anhydrase 1 [Source:HGNC Symbol;Acc:HGNC:1368]",{"v":2.3649,"d":"2.36"},0,"inf","inf",1,1,"up","no"]
[170545,0,"chr6","-",159035137,159045152,"ENST00000326965",9,3051,"MSTRG.13398","TAGAP","GO:0007165(signal transduction);GO:0043547(positive regulation of GTPase activity);GO:0005085(guanyl-nucleotide exchange factor activity);GO:0005829(cytosol);GO:0005096(GTPase activator activity);GO:0051056(regulation of small GTPase mediated signal transduction)","NA","NA","NA","T-cell activation RhoGTPase activating protein [Source:HGNC Symbol;Acc:HGNC:15669]",0,{"v":3.704418,"d":"3.70"},"-inf","-inf",1,1,"down","no"]
[107650,0,"chr2","-",20499571,20501311,"ENST00000441870",2,686,"ENSG00000227047","AC012065.1","NA","NA","NA","NA","NA",0,{"v":0.040697,"d":"0.04"},"-inf","-inf",1,1,"down","no"]
[4380,0,"chr1","-",37566821,37568417,"ENST00000479255",3,422,"MSTRG.428","GNL2","GO:0003723(RNA binding);GO:0005634(nucleus);GO:0016020(membrane);GO:0005525(GTP binding);GO:0000166(nucleotide binding);GO:0005730(nucleolus);GO:0003924(GTPase activity);GO:0042254(ribosome biogenesis);GO:0008150(biological_process);GO:0016021(integral component of membrane)","03008(Ribosome biogenesis in eukaryotes)","NA","NA","G protein nucleolar 2 [Source:HGNC Symbol;Acc:HGNC:29925]",{"v":0.243731,"d":"0.24"},0,"inf","inf",1,1,"up","no"]
[127360,0,"chr21","+",41402634,41408943,"ENST00000398632",3,2211,"MSTRG.10063","MX2","GO:0006810(transport);GO:0051028(mRNA transport);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0015031(protein transport);GO:0005525(GTP binding);GO:0000166(nucleotide binding);GO:0003924(GTPase activity);GO:0005515(protein binding);GO:0005643(nuclear pore);GO:0002376(immune system process);GO:0045087(innate immune response);GO:0051607(defense response to virus);GO:0005829(cytosol);GO:0008017(microtubule binding);GO:0009615(response to virus);GO:0051726(regulation of cell cycle);GO:0006952(defense response);GO:0060337(type I interferon signaling pathway);GO:0003374(dynamin family protein polymerization involved in mitochondrial fission);GO:0061025(membrane fusion);GO:0031966(mitochondrial membrane);GO:0035455(response to interferon-alpha);GO:0000266(mitochondrial fission);GO:0046822(regulation of nucleocytoplasmic transport)","NA","NA","NA","MX dynamin like GTPase 2 [Source:HGNC Symbol;Acc:HGNC:7533]",{"v":0.141684,"d":"0.14"},{"v":0.312694,"d":"0.31"},{"v":0.45310751085726,"d":"0.45"},{"v":-1.1420746892563,"d":"-1.14"},1,1,"down","no"]
[121367,0,"chr20","+",408343,410764,"ENST00000400247",2,790,"MSTRG.9535","RBCK1","GO:0046872(metal ion binding);GO:0016740(transferase activity);GO:0005515(protein binding);GO:0005829(cytosol);GO:0000209(protein polyubiquitination);GO:0032088(negative regulation of NF-kappaB transcription factor activity);GO:0016032(viral process);GO:0043123(positive regulation of I-kappaB kinase/NF-kappaB signaling);GO:0043130(ubiquitin binding);GO:0051092(positive regulation of NF-kappaB transcription factor activity);GO:0007249(I-kappaB kinase/NF-kappaB signaling);GO:0004842(ubiquitin-protein transferase activity);GO:0043161(proteasome-mediated ubiquitin-dependent protein catabolic process);GO:0050852(T cell receptor signaling pathway);GO:0010803(regulation of tumor necrosis factor-mediated signaling pathway);GO:0097039(protein linear polyubiquitination);GO:0071797(LUBAC complex);GO:0042346(positive regulation of NF-kappaB import into nucleus);GO:0043065(positive regulation of apoptotic process);GO:0060546(negative regulation of necroptotic process);GO:2001238(positive regulation of extrinsic apoptotic signaling pathway)","04217(Necroptosis);04621(NOD-like receptor signaling pathway)","NA","NA","RANBP2-type and C3HC4-type zinc finger containing 1 [Source:HGNC Symbol;Acc:HGNC:15864]",{"v":0.18709,"d":"0.19"},{"v":0.06547,"d":"0.07"},{"v":2.85764472277379,"d":"2.86"},{"v":1.51482656424586,"d":"1.51"},1,1,"up","no"]
[144565,0,"chr3","-",195971253,195975902,"ENST00000457601",3,560,"ENSG00000185485","SDHAP1","NA","NA","NA","NA","succinate dehydrogenase complex flavoprotein subunit A pseudogene 1 [Source:HGNC Symbol;Acc:HGNC:32455]",{"v":0.389968,"d":"0.39"},{"v":0.807066,"d":"0.81"},{"v":0.483192204850657,"d":"0.48"},{"v":-1.04933091446695,"d":"-1.05"},1,1,"down","no"]
[104682,0,"chr19","+",51415906,51417425,"ENST00000532688",3,729,"MSTRG.8377","AC008750.2","NA","NA","NA","NA","NA",{"v":0.131612,"d":"0.13"},{"v":0.089886,"d":"0.09"},{"v":1.46421022183655,"d":"1.46"},{"v":0.550122701318753,"d":"0.55"},1,1,"up","no"]
[98902,0,"chr19","+",19344252,19357755,"ENST00000262816",9,3838,"MSTRG.8017","MAU2","GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0051301(cell division);GO:0007049(cell cycle);GO:0016604(nuclear body);GO:0003690(double-stranded DNA binding);GO:0007059(chromosome segregation);GO:0005515(protein binding);GO:0007064(mitotic sister chromatid cohesion);GO:0047485(protein N-terminus binding);GO:0000785(chromatin);GO:0034088(maintenance of mitotic sister chromatid cohesion);GO:0032116(SMC loading complex)","NA","NA","NA","MAU2 sister chromatid cohesion factor [Source:HGNC Symbol;Acc:HGNC:29140]",{"v":0.017231,"d":"0.02"},{"v":0.023466,"d":"0.02"},{"v":0.73429642887582,"d":"0.73"},{"v":-0.445565511196305,"d":"-0.45"},1,1,"down","no"]
[97590,0,"chr19","-",14477764,14480596,"ENST00000585606",3,2071,"MSTRG.7903","GIPC1","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005829(cytosol);GO:0005515(protein binding);GO:0007186(G-protein coupled receptor signaling pathway);GO:0031410(cytoplasmic vesicle);GO:0003779(actin binding);GO:0017022(myosin binding);GO:0030165(PDZ domain binding);GO:0042803(protein homodimerization activity);GO:0006605(protein targeting);GO:0007268(chemical synaptic transmission);GO:0014047(glutamate secretion);GO:0030511(positive regulation of transforming growth factor beta receptor signaling pathway);GO:0031647(regulation of protein stability);GO:0032435(negative regulation of proteasomal ubiquitin-dependent protein catabolic process);GO:0043542(endothelial cell migration);GO:0048167(regulation of synaptic plasticity);GO:0005903(brush border);GO:0008021(synaptic vesicle);GO:0012506(vesicle membrane);GO:0030139(endocytic vesicle);GO:0043197(dendritic spine);GO:0043198(dendritic shaft);GO:0045296(cadherin binding);GO:0070062(extracellular exosome);GO:0005938(cell cortex);GO:0005102(receptor binding);GO:0032467(positive regulation of cytokinesis)","NA","NA","NA","GIPC PDZ domain containing family member 1 [Source:HGNC Symbol;Acc:HGNC:1226]",{"v":0.016814,"d":"0.02"},{"v":0.081663,"d":"0.08"},{"v":0.205894958549159,"d":"0.21"},{"v":-2.28001958966305,"d":"-2.28"},1,1,"down","no"]
[158911,0,"chr5","-",139108007,139196528,"ENST00000504666",4,547,"MSTRG.12379","SIL1","GO:0006810(transport);GO:0015031(protein transport);GO:0005783(endoplasmic reticulum);GO:0005515(protein binding);GO:0005615(extracellular space);GO:0006886(intracellular protein transport);GO:0005788(endoplasmic reticulum lumen);GO:0006457(protein folding);GO:0051082(unfolded protein binding)","04141(Protein processing in endoplasmic reticulum)","NA","NA","SIL1 nucleotide exchange factor [Source:HGNC Symbol;Acc:HGNC:24624]",0,0,1,0,1,1,"no","no"]
[102275,0,"chr19","-",43501530,43504644,"ENST00000596902",4,808,"ENSG00000176531","PHLDB3","GO:0019899(enzyme binding)","NA","NA","NA","pleckstrin homology like domain family B member 3 [Source:HGNC Symbol;Acc:HGNC:30499]",0,{"v":0.035361,"d":"0.04"},"-inf","-inf",1,1,"down","no"]
[174886,0,"chr7","-",73570886,73578619,"ENST00000426966",8,1196,"ENSG00000106638","TBL2","GO:0003723(RNA binding);GO:0005783(endoplasmic reticulum);GO:0019901(protein kinase binding);GO:0042149(cellular response to glucose starvation);GO:0030176(integral component of endoplasmic reticulum membrane);GO:0071456(cellular response to hypoxia);GO:0031369(translation initiation factor binding);GO:0030968(endoplasmic reticulum unfolded protein response);GO:0051219(phosphoprotein binding)","NA","NA","NA","transducin beta like 2 [Source:HGNC Symbol;Acc:HGNC:11586]",{"v":0.249999,"d":"0.25"},0,"inf","inf",1,1,"up","no"]
[196091,0,"chrX","+",21855987,21858727,"ENST00000429584",1,2741,"ENSG00000230797","YY2","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006366(transcription from RNA polymerase II promoter);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0001228(transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding);GO:0043565(sequence-specific DNA binding);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0000987(core promoter proximal region sequence-specific DNA binding)","NA","NA","NA","YY2 transcription factor [Source:HGNC Symbol;Acc:HGNC:31684]",0,0,1,0,1,1,"no","no"]
[51893,0,"chr13","+",112873432,112876094,"ENST00000495930",2,564,"ENSG00000068650","ATP11A","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0043231(intracellular membrane-bounded organelle);GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0000287(magnesium ion binding);GO:0016787(hydrolase activity);GO:0005765(lysosomal membrane);GO:0005783(endoplasmic reticulum);GO:0005886(plasma membrane);GO:0006869(lipid transport);GO:0004012(phospholipid-translocating ATPase activity);GO:0015914(phospholipid transport);GO:0005515(protein binding);GO:0005768(endosome);GO:0005769(early endosome);GO:0055037(recycling endosome);GO:0043312(neutrophil degranulation);GO:0035579(specific granule membrane);GO:0070821(tertiary granule membrane);GO:0045332(phospholipid translocation)","NA","NA","NA","ATPase phospholipid transporting 11A [Source:HGNC Symbol;Acc:HGNC:13552]",0,{"v":0.239741,"d":"0.24"},"-inf","-inf",1,1,"down","no"]
[123305,0,"chr20","-",35630983,35664916,"ENST00000414664",11,1070,"MSTRG.9710","CPNE1","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005654(nucleoplasm);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0031965(nuclear membrane);GO:0005829(cytosol);GO:0042803(protein homodimerization activity);GO:0005886(plasma membrane);GO:0006508(proteolysis);GO:0030154(cell differentiation);GO:0005509(calcium ion binding);GO:0005515(protein binding);GO:0070062(extracellular exosome);GO:0043312(neutrophil degranulation);GO:0010629(negative regulation of gene expression);GO:0005215(transporter activity);GO:0016192(vesicle-mediated transport);GO:0035577(azurophil granule membrane);GO:0006629(lipid metabolic process);GO:0004175(endopeptidase activity);GO:0051897(positive regulation of protein kinase B signaling);GO:0051059(NF-kappaB binding);GO:0043122(regulation of I-kappaB kinase/NF-kappaB signaling);GO:0071277(cellular response to calcium ion);GO:1901223(negative regulation of NIK/NF-kappaB signaling);GO:0005544(calcium-dependent phospholipid binding);GO:0046474(glycerophospholipid biosynthetic process);GO:0043392(negative regulation of DNA binding);GO:1903265(positive regulation of tumor necrosis factor-mediated signaling pathway);GO:0045666(positive regulation of neuron differentiation);GO:1990138(neuron projection extension);GO:0001786(phosphatidylserine binding)","NA","NA","NA","copine 1 [Source:HGNC Symbol;Acc:HGNC:2314]",{"v":0.351617,"d":"0.35"},0,"inf","inf",1,1,"up","no"]
[189432,0,"chr9","+",21994791,22121095,"ENST00000428597",19,3835,"ENSG00000240498","CDKN2B-AS1","NA","NA","NA","NA","CDKN2B antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:34341]",{"v":0.072244,"d":"0.07"},0,"inf","inf",1,1,"up","no"]
[92752,0,"chr18","-",56040332,56068370,"ENST00000589754",3,555,"ENSG00000206129","AC006305.1","NA","NA","NA","NA","NA",{"v":0.081298,"d":"0.08"},0,"inf","inf",1,1,"up","no"]
[52680,0,"chr14","-",21461245,21476673,"ENST00000461909",7,630,"MSTRG.4155","RAB2B","GO:0006810(transport);GO:0016020(membrane);GO:0015031(protein transport);GO:0005525(GTP binding);GO:0000166(nucleotide binding);GO:0003924(GTPase activity);GO:0005794(Golgi apparatus);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0000139(Golgi membrane);GO:0016192(vesicle-mediated transport);GO:0070062(extracellular exosome);GO:0045921(positive regulation of exocytosis)","NA","NA","NA","RAB2B, member RAS oncogene family [Source:HGNC Symbol;Acc:HGNC:20246]",{"v":3.061652,"d":"3.06"},{"v":0.885339,"d":"0.89"},{"v":3.45816913069457,"d":"3.46"},{"v":1.79000842943346,"d":"1.79"},1,1,"up","no"]
[83554,0,"chr17","+",42480263,42487353,"ENST00000587882",3,780,"MSTRG.6830","ATP6V0A1","GO:0006810(transport);GO:0016607(nuclear speck);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005794(Golgi apparatus);GO:0043231(intracellular membrane-bounded organelle);GO:0005829(cytosol);GO:0006811(ion transport);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0042470(melanosome);GO:0030659(cytoplasmic vesicle membrane);GO:0031410(cytoplasmic vesicle);GO:0015078(hydrogen ion transmembrane transporter activity);GO:0015991(ATP hydrolysis coupled proton transport);GO:0015992(proton transport);GO:0000220(vacuolar proton-transporting V-type ATPase, V0 domain);GO:0033179(proton-transporting V-type ATPase, V0 domain);GO:0070062(extracellular exosome);GO:0034220(ion transmembrane transport);GO:0010008(endosome membrane);GO:0043312(neutrophil degranulation);GO:0030670(phagocytic vesicle membrane);GO:0030667(secretory granule membrane);GO:0008286(insulin receptor signaling pathway);GO:0016241(regulation of macroautophagy);GO:0033572(transferrin transport);GO:0090383(phagosome acidification);GO:0101003(ficolin-1-rich granule membrane);GO:0051117(ATPase binding);GO:0015986(ATP synthesis coupled proton transport);GO:0005765(lysosomal membrane);GO:0046961(proton-transporting ATPase activity, rotational mechanism);GO:0070072(vacuolar proton-transporting V-type ATPase complex assembly);GO:0016471(vacuolar proton-transporting V-type ATPase complex);GO:0007035(vacuolar acidification);GO:1901998(toxin transport);GO:0005737(cytoplasm)","00190(Oxidative phosphorylation);04145(Phagosome);04142(Lysosome);04966(Collecting duct acid secretion);04721(Synaptic vesicle cycle);05323(Rheumatoid arthritis);05110(Vibrio cholerae infection);05120(Epithelial cell signaling in Helicobacter pylori infection);05152(Tuberculosis);05165(Human papillomavirus infection)","NA","NA","ATPase H+ transporting V0 subunit a1 [Source:HGNC Symbol;Acc:HGNC:865]",{"v":0.1977,"d":"0.20"},0,"inf","inf",1,1,"up","no"]
[12003,0,"chr1","+",156212993,156240040,"ENST00000368279",5,1019,"MSTRG.1073","PMF1","GO:0005634(nucleus);GO:0005794(Golgi apparatus);GO:0043231(intracellular membrane-bounded organelle);GO:0005654(nucleoplasm);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0051301(cell division);GO:0005694(chromosome);GO:0005515(protein binding);GO:0007049(cell cycle);GO:0003713(transcription coactivator activity);GO:0007059(chromosome segregation);GO:0000775(chromosome, centromeric region);GO:0000776(kinetochore);GO:0000777(condensed chromosome kinetochore);GO:0005829(cytosol);GO:0007062(sister chromatid cohesion);GO:0006366(transcription from RNA polymerase II promoter);GO:0043522(leucine zipper domain binding);GO:0005667(transcription factor complex);GO:0000444(MIS12/MIND type complex)","NA","NA","NA","polyamine modulated factor 1 [Source:HGNC Symbol;Acc:HGNC:9112]",{"v":0.163934,"d":"0.16"},0,"inf","inf",1,1,"up","no"]
[143850,0,"chr3","+",186783305,186785047,"ENST00000445596",4,600,"MSTRG.11403","EIF4A2","GO:0003676(nucleic acid binding);GO:0005524(ATP binding);GO:0003723(RNA binding);GO:0003743(translation initiation factor activity);GO:0006412(translation);GO:0006413(translational initiation);GO:0000166(nucleotide binding);GO:0016787(hydrolase activity);GO:0004386(helicase activity);GO:0005515(protein binding);GO:0048471(perinuclear region of cytoplasm);GO:0005730(nucleolus);GO:0005829(cytosol);GO:0004004(ATP-dependent RNA helicase activity);GO:0010501(RNA secondary structure unwinding);GO:0000289(nuclear-transcribed mRNA poly(A) tail shortening);GO:0016032(viral process);GO:0016887(ATPase activity);GO:0006446(regulation of translational initiation);GO:0016281(eukaryotic translation initiation factor 4F complex);GO:1900260(negative regulation of RNA-directed 5'-3' RNA polymerase activity);GO:1990830(cellular response to leukemia inhibitory factor)","03013(RNA transport)","NA","NA","eukaryotic translation initiation factor 4A2 [Source:HGNC Symbol;Acc:HGNC:3284]",{"v":0.038139,"d":"0.04"},0,"inf","inf",1,1,"up","no"]
[137335,0,"chr3","+",54987678,55074216,"ENST00000478261",7,760,"ENSG00000157445","CACNA2D3","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0046872(metal ion binding);GO:0005244(voltage-gated ion channel activity);GO:0006811(ion transport);GO:0034765(regulation of ion transmembrane transport);GO:0006816(calcium ion transport);GO:0005262(calcium channel activity);GO:0070588(calcium ion transmembrane transport);GO:0005886(plasma membrane);GO:0061337(cardiac conduction)","04010(MAPK signaling pathway);04921(Oxytocin signaling pathway);04260(Cardiac muscle contraction);04261(Adrenergic signaling in cardiomyocytes);05410(Hypertrophic cardiomyopathy (HCM));05412(Arrhythmogenic right ventricular cardiomyopathy (ARVC));05414(Dilated cardiomyopathy (DCM))","NA","NA","calcium voltage-gated channel auxiliary subunit alpha2delta 3 [Source:HGNC Symbol;Acc:HGNC:15460]",0,{"v":0.297668,"d":"0.30"},"-inf","-inf",1,1,"down","no"]
[152669,0,"chr4","+",185018841,185020802,"ENST00000513599",3,1099,"ENSG00000187821","HELT","GO:0005634(nucleus);GO:0046983(protein dimerization activity);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:0001078(transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0042803(protein homodimerization activity);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0001967(suckling behavior);GO:0007417(central nervous system development);GO:0009791(post-embryonic development);GO:0010259(multicellular organism aging);GO:0010467(gene expression);GO:0021858(GABAergic neuron differentiation in basal ganglia);GO:0030182(neuron differentiation);GO:0035264(multicellular organism growth);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0005667(transcription factor complex)","NA","NA","NA","helt bHLH transcription factor [Source:HGNC Symbol;Acc:HGNC:33783]",0,{"v":0.028603,"d":"0.03"},"-inf","-inf",1,1,"down","no"]
[167043,0,"chr6","-",67887646,67889339,"ENST00000412872",2,1605,"ENSG00000227706","AL713998.1","NA","NA","NA","NA","NA",{"v":0.0268,"d":"0.03"},0,"inf","inf",1,1,"up","no"]
[54988,0,"chr14","+",51847126,51979342,"ENST00000553560",4,479,"MSTRG.4391","GNG2","GO:0016020(membrane);GO:0007186(G-protein coupled receptor signaling pathway);GO:0004871(signal transducer activity);GO:0005886(plasma membrane);GO:0007165(signal transduction);GO:0005834(heterotrimeric G-protein complex);GO:0070062(extracellular exosome);GO:0006457(protein folding);GO:0030168(platelet activation);GO:0071377(cellular response to glucagon stimulus);GO:0071380(cellular response to prostaglandin E stimulus);GO:0071870(cellular response to catecholamine stimulus);GO:0007223(Wnt signaling pathway, calcium modulating pathway);GO:0031681(G-protein beta-subunit binding);GO:0007191(adenylate cyclase-activating dopamine receptor signaling pathway);GO:0008283(cell proliferation)","04014(Ras signaling pathway);04371(Apelin signaling pathway);04151(PI3K-Akt signaling pathway);04062(Chemokine signaling pathway);04926(Relaxin signaling pathway);04724(Glutamatergic synapse);04727(GABAergic synapse);04725(Cholinergic synapse);04728(Dopaminergic synapse);04726(Serotonergic synapse);04723(Retrograde endocannabinoid signaling);04713(Circadian entrainment);05200(Pathways in cancer);05032(Morphine addiction);05034(Alcoholism);05167(Kaposi's sarcoma-associated herpesvirus infection)","NA","NA","G protein subunit gamma 2 [Source:HGNC Symbol;Acc:HGNC:4404]",0,{"v":0.033352,"d":"0.03"},"-inf","-inf",1,1,"down","no"]
[11655,0,"chr1","-",155200899,155203305,"ENST00000460050",8,879,"MSTRG.1034","THBS3","GO:0005509(calcium ion binding);GO:0007155(cell adhesion);GO:0005576(extracellular region);GO:0048471(perinuclear region of cytoplasm);GO:0008201(heparin binding);GO:0007160(cell-matrix adhesion);GO:0003417(growth plate cartilage development);GO:0043931(ossification involved in bone maturation);GO:0060346(bone trabecula formation)","04151(PI3K-Akt signaling pathway);04512(ECM-receptor interaction);04145(Phagosome);04510(Focal adhesion);05165(Human papillomavirus infection);05144(Malaria)","NA","NA","thrombospondin 3 [Source:HGNC Symbol;Acc:HGNC:11787]",0,0,1,0,1,1,"no","no"]
[56927,0,"chr14","+",75069280,75079987,"ENST00000524913",3,4283,"MSTRG.4550","ZC2HC1C","GO:0046872(metal ion binding);GO:0005515(protein binding)","NA","NA","NA","zinc finger C2HC-type containing 1C [Source:HGNC Symbol;Acc:HGNC:20354]",{"v":0.047005,"d":"0.05"},{"v":0.027629,"d":"0.03"},{"v":1.70129212059792,"d":"1.70"},{"v":0.766630880421701,"d":"0.77"},1,1,"up","no"]
[71410,0,"chr16","+",28951007,28952562,"ENST00000565752",2,823,"MSTRG.5781","NFATC2IP","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016925(protein sumoylation);GO:0031386(protein tag);GO:0001816(cytokine production);GO:0045944(positive regulation of transcription from RNA polymerase II promoter)","NA","NA","NA","nuclear factor of activated T-cells 2 interacting protein [Source:HGNC Symbol;Acc:HGNC:25906]",{"v":0.087816,"d":"0.09"},{"v":0.733173,"d":"0.73"},{"v":0.119775278140357,"d":"0.12"},{"v":-3.06159793120835,"d":"-3.06"},1,1,"down","no"]
[90230,0,"chr18","+",2578123,2579196,"ENST00000574567",2,289,"ENSG00000080986","NDC80","GO:0005634(nucleus);GO:0016020(membrane);GO:0005654(nucleoplasm);GO:0051301(cell division);GO:0005694(chromosome);GO:0005813(centrosome);GO:0005515(protein binding);GO:0007049(cell cycle);GO:0042802(identical protein binding);GO:0007059(chromosome segregation);GO:0000775(chromosome, centromeric region);GO:0000776(kinetochore);GO:0000777(condensed chromosome kinetochore);GO:0005829(cytosol);GO:0005200(structural constituent of cytoskeleton);GO:0007052(mitotic spindle organization);GO:0007062(sister chromatid cohesion);GO:0000070(mitotic sister chromatid segregation);GO:0000132(establishment of mitotic spindle orientation);GO:0000278(mitotic cell cycle);GO:0008608(attachment of spindle microtubules to kinetochore);GO:0051310(metaphase plate congression);GO:0051315(attachment of mitotic spindle microtubules to kinetochore);GO:0051383(kinetochore organization);GO:0090267(positive regulation of mitotic cell cycle spindle assembly checkpoint);GO:1905342(positive regulation of protein localization to kinetochore);GO:0000942(condensed nuclear chromosome outer kinetochore);GO:0031262(Ndc80 complex)","NA","NA","NA","NDC80, kinetochore complex component [Source:HGNC Symbol;Acc:HGNC:16909]",0,0,1,0,1,1,"no","no"]
[2222,0,"chr1","+",19210501,19240704,"ENST00000437898",2,507,"MSTRG.207","AL035413.1","NA","NA","NA","NA","NA",{"v":0.117944,"d":"0.12"},{"v":0.647277,"d":"0.65"},{"v":0.18221565110455,"d":"0.18"},{"v":-2.45628121257964,"d":"-2.46"},1,1,"down","no"]
[67542,0,"chr16","+",668105,671162,"ENST00000563776",9,923,"MSTRG.5485","RHOT2","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005525(GTP binding);GO:0007264(small GTPase mediated signal transduction);GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0016787(hydrolase activity);GO:0005509(calcium ion binding);GO:0003924(GTPase activity);GO:0005739(mitochondrion);GO:0005515(protein binding);GO:0005741(mitochondrial outer membrane);GO:0007005(mitochondrion organization);GO:0005886(plasma membrane);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0051056(regulation of small GTPase mediated signal transduction);GO:0047497(mitochondrion transport along microtubule);GO:0031307(integral component of mitochondrial outer membrane);GO:0019725(cellular homeostasis);GO:0097345(mitochondrial outer membrane permeabilization)","04137(Mitophagy - animal)","NA","NA","ras homolog family member T2 [Source:HGNC Symbol;Acc:HGNC:21169]",0,0,1,0,1,1,"no","no"]
[183872,0,"chr8","-",53993704,54021929,"ENST00000521836",4,625,"MSTRG.14356","TCEA1","GO:0005634(nucleus);GO:0003676(nucleic acid binding);GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0005730(nucleolus);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0005654(nucleoplasm);GO:0006366(transcription from RNA polymerase II promoter);GO:0006368(transcription elongation from RNA polymerase II promoter);GO:0006283(transcription-coupled nucleotide-excision repair);GO:0005669(transcription factor TFIID complex);GO:0003746(translation elongation factor activity);GO:0006414(translational elongation)","NA","NA","NA","transcription elongation factor A1 [Source:HGNC Symbol;Acc:HGNC:11612]",{"v":0.225367,"d":"0.23"},{"v":1.699268,"d":"1.70"},{"v":0.132625930694864,"d":"0.13"},{"v":-2.91456521968207,"d":"-2.91"},1,1,"down","no"]
[85938,0,"chr17","-",57078298,57085022,"ENST00000576871",3,713,"ENSG00000263004","AC007114.1","NA","NA","NA","NA","NA",{"v":0.141301,"d":"0.14"},{"v":0.15759,"d":"0.16"},{"v":0.896636842439241,"d":"0.90"},{"v":-0.157404314534711,"d":"-0.16"},1,1,"down","no"]
[89779,0,"chr17","+",82229062,82236895,"ENST00000578574",2,958,"MSTRG.7355","SLC16A3","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0055085(transmembrane transport);GO:0005887(integral component of plasma membrane);GO:0008028(monocarboxylic acid transmembrane transporter activity);GO:0015129(lactate transmembrane transporter activity);GO:0015718(monocarboxylic acid transport);GO:0035873(lactate transmembrane transport);GO:0003723(RNA binding);GO:0006810(transport);GO:0031965(nuclear membrane);GO:0005886(plasma membrane);GO:0015293(symporter activity);GO:0005515(protein binding);GO:0050900(leukocyte migration);GO:0006090(pyruvate metabolic process);GO:0035879(plasma membrane lactate transport)","05230(Central carbon metabolism in cancer)","NA","NA","solute carrier family 16 member 3 [Source:HGNC Symbol;Acc:HGNC:10924]",{"v":0.149505,"d":"0.15"},{"v":0.020336,"d":"0.02"},{"v":7.35174075531078,"d":"7.35"},{"v":2.87808589371865,"d":"2.88"},1,1,"up","no"]
[14680,0,"chr1","-",200666259,200669708,"ENST00000436897",2,635,"MSTRG.1279","DDX59","GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0016787(hydrolase activity);GO:0004386(helicase activity);GO:0005730(nucleolus);GO:0004004(ATP-dependent RNA helicase activity);GO:0010501(RNA secondary structure unwinding);GO:0005622(intracellular);GO:0016020(membrane);GO:0016021(integral component of membrane)","NA","NA","NA","DEAD-box helicase 59 [Source:HGNC Symbol;Acc:HGNC:25360]",{"v":0.403268,"d":"0.40"},{"v":0.084122,"d":"0.08"},{"v":4.79384703169207,"d":"4.79"},{"v":2.26118387433118,"d":"2.26"},1,1,"up","no"]
[126384,0,"chr21","-",28966895,28986761,"ENST00000483326",10,1753,"ENSG00000198862","LTN1","GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0016740(transferase activity);GO:0016567(protein ubiquitination);GO:0005515(protein binding);GO:0004842(ubiquitin-protein transferase activity);GO:0061630(ubiquitin protein ligase activity);GO:0051865(protein autoubiquitination)","NA","NA","NA","listerin E3 ubiquitin protein ligase 1 [Source:HGNC Symbol;Acc:HGNC:13082]",{"v":0.010834,"d":"0.01"},0,"inf","inf",1,1,"up","no"]
[89468,0,"chr17","-",81843166,81847327,"ENST00000415593",7,1669,"MSTRG.7333","P4HB","GO:0003723(RNA binding);GO:0016020(membrane);GO:0016853(isomerase activity);GO:0005783(endoplasmic reticulum);GO:0045454(cell redox homeostasis);GO:0005886(plasma membrane);GO:0055114(oxidation-reduction process);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0042470(melanosome);GO:0051213(dioxygenase activity);GO:0003756(protein disulfide isomerase activity);GO:0005178(integrin binding);GO:0019899(enzyme binding);GO:0046982(protein heterodimerization activity);GO:0009897(external side of plasma membrane);GO:0034663(endoplasmic reticulum chaperone complex);GO:0005925(focal adhesion);GO:0005788(endoplasmic reticulum lumen);GO:0070062(extracellular exosome);GO:0044267(cellular protein metabolic process);GO:0043687(post-translational protein modification);GO:0031012(extracellular matrix);GO:0035722(interleukin-12-mediated signaling pathway);GO:0046598(positive regulation of viral entry into host cell);GO:0034599(cellular response to oxidative stress);GO:0071456(cellular response to hypoxia);GO:0034976(response to endoplasmic reticulum stress);GO:0006457(protein folding);GO:0005793(endoplasmic reticulum-Golgi intermediate compartment);GO:0004656(procollagen-proline 4-dioxygenase activity);GO:0034378(chylomicron assembly);GO:0034379(very-low-density lipoprotein particle assembly);GO:0015037(peptide disulfide oxidoreductase activity);GO:0018401(peptidyl-proline hydroxylation to 4-hydroxy-L-proline);GO:1902175(regulation of oxidative stress-induced intrinsic apoptotic signaling pathway);GO:0016222(procollagen-proline 4-dioxygenase complex);GO:0005623(cell)","04141(Protein processing in endoplasmic reticulum)","NA","NA","prolyl 4-hydroxylase subunit beta [Source:HGNC Symbol;Acc:HGNC:8548]",{"v":0.078665,"d":"0.08"},0,"inf","inf",1,1,"up","no"]
[76373,0,"chr16","+",84733209,84744911,"ENST00000563023",2,574,"MSTRG.6197","USP10","GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0016579(protein deubiquitination);GO:0016787(hydrolase activity);GO:0005515(protein binding);GO:0008233(peptidase activity);GO:0008234(cysteine-type peptidase activity);GO:0006508(proteolysis);GO:0006281(DNA repair);GO:0006974(cellular response to DNA damage stimulus);GO:0006511(ubiquitin-dependent protein catabolic process);GO:0036459(thiol-dependent ubiquitinyl hydrolase activity);GO:0006914(autophagy);GO:0005768(endosome);GO:0044325(ion channel binding);GO:0043234(protein complex);GO:0005769(early endosome);GO:0071347(cellular response to interleukin-1);GO:0004843(thiol-dependent ubiquitin-specific protease activity);GO:0010506(regulation of autophagy);GO:0043124(negative regulation of I-kappaB kinase/NF-kappaB signaling);GO:0019985(translesion synthesis);GO:0030330(DNA damage response, signal transduction by p53 class mediator);GO:0002039(p53 binding);GO:0004197(cysteine-type endopeptidase activity)","NA","NA","NA","ubiquitin specific peptidase 10 [Source:HGNC Symbol;Acc:HGNC:12608]",0,{"v":0.000318,"d":"0.00"},"-inf","-inf",1,1,"down","no"]
[197950,0,"chrX","+",68499034,68515340,"ENST00000470730",3,2267,"ENSG00000181704","YIPF6","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005515(protein binding);GO:0005783(endoplasmic reticulum);GO:0042802(identical protein binding);GO:0060576(intestinal epithelial cell development);GO:0005801(cis-Golgi network);GO:0005802(trans-Golgi network);GO:0030134(ER to Golgi transport vesicle)","NA","NA","NA","Yip1 domain family member 6 [Source:HGNC Symbol;Acc:HGNC:28304]",0,{"v":0.002414,"d":"0.00"},"-inf","-inf",1,1,"down","no"]
[84277,0,"chr17","-",44850810,44863595,"ENST00000586276",11,3678,"MSTRG.6910","EFTUD2","GO:0003723(RNA binding);GO:0006397(mRNA processing);GO:0008380(RNA splicing);GO:0005634(nucleus);GO:0016607(nuclear speck);GO:0016020(membrane);GO:0005525(GTP binding);GO:0000166(nucleotide binding);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0003924(GTPase activity);GO:0005515(protein binding);GO:0005681(spliceosomal complex);GO:0031012(extracellular matrix);GO:0000398(mRNA splicing, via spliceosome);GO:0015030(Cajal body);GO:0046540(U4/U6 x U5 tri-snRNP complex);GO:0071013(catalytic step 2 spliceosome);GO:0035690(cellular response to drug);GO:0042220(response to cocaine)","03040(Spliceosome)","NA","NA","elongation factor Tu GTP binding domain containing 2 [Source:HGNC Symbol;Acc:HGNC:30858]",{"v":0.003122,"d":"0.00"},{"v":0.071128,"d":"0.07"},{"v":0.0438927004836351,"d":"0.04"},{"v":-4.50987515551937,"d":"-4.51"},1,1,"down","no"]
[18911,0,"chr10","-",18513115,18545651,"ENST00000425669",5,1028,"ENSG00000240291","AL450384.2","NA","NA","NA","NA","NA",{"v":1.268814,"d":"1.27"},{"v":0.238819,"d":"0.24"},{"v":5.31286874159929,"d":"5.31"},{"v":2.40949107038994,"d":"2.41"},1,1,"up","no"]
[25623,0,"chr11","-",3775894,3797552,"ENST00000532475",5,553,"MSTRG.2149","NUP98","GO:0006810(transport);GO:0051028(mRNA transport);GO:0005634(nucleus);GO:0016020(membrane);GO:0015031(protein transport);GO:0043231(intracellular membrane-bounded organelle);GO:0005654(nucleoplasm);GO:0016787(hydrolase activity);GO:0030529(intracellular ribonucleoprotein complex);GO:0005643(nuclear pore);GO:0008233(peptidase activity);GO:0006508(proteolysis);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0006260(DNA replication);GO:0008236(serine-type peptidase activity);GO:0000776(kinetochore);GO:0003729(mRNA binding);GO:0003723(RNA binding);GO:0005515(protein binding);GO:0005829(cytosol);GO:0075733(intracellular transport of virus);GO:0043657(host cell);GO:0016032(viral process);GO:0008139(nuclear localization sequence binding);GO:0007062(sister chromatid cohesion);GO:0031965(nuclear membrane);GO:0005215(transporter activity);GO:0005635(nuclear envelope);GO:0006406(mRNA export from nucleus);GO:0001105(RNA polymerase II transcription coactivator activity);GO:0016925(protein sumoylation);GO:0006606(protein import into nucleus);GO:0060964(regulation of gene silencing by miRNA);GO:0006110(regulation of glycolytic process);GO:0006409(tRNA export from nucleus);GO:0007077(mitotic nuclear envelope disassembly);GO:0019083(viral transcription);GO:1900034(regulation of cellular response to heat);GO:1990841(promoter-specific chromatin binding);GO:0006913(nucleocytoplasmic transport);GO:0016604(nuclear body);GO:0042405(nuclear inclusion body);GO:0006405(RNA export from nucleus);GO:0034399(nuclear periphery);GO:0006999(nuclear pore organization);GO:0044615(nuclear pore nuclear basket);GO:0048026(positive regulation of mRNA splicing, via spliceosome);GO:0005487(nucleocytoplasmic transporter activity);GO:0017056(structural constituent of nuclear pore);GO:0051292(nuclear pore complex assembly);GO:0044614(nuclear pore cytoplasmic filaments);GO:0042277(peptide binding);GO:0000973(posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery);GO:0034398(telomere tethering at nuclear periphery);GO:0031080(nuclear pore outer ring)","03013(RNA transport);05164(Influenza A)","NA","NA","nucleoporin 98 [Source:HGNC Symbol;Acc:HGNC:8068]",0,{"v":0.192972,"d":"0.19"},"-inf","-inf",1,1,"down","no"]
[126435,0,"chr21","+",29193494,29288205,"ENST00000420364",2,989,"MSTRG.9981","LINC00189","NA","NA","NA","NA","long intergenic non-protein coding RNA 189 [Source:HGNC Symbol;Acc:HGNC:18461]",0,0,1,0,1,1,"no","no"]
[76583,0,"chr16","-",87386011,87392142,"ENST00000567622",4,438,"MSTRG.6210","FBXO31","GO:0016567(protein ubiquitination);GO:0006974(cellular response to DNA damage stimulus);GO:0007049(cell cycle);GO:0030332(cyclin binding);GO:0031146(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process);GO:0031571(mitotic G1 DNA damage checkpoint);GO:0019005(SCF ubiquitin ligase complex);GO:0005829(cytosol);GO:0000209(protein polyubiquitination);GO:0043687(post-translational protein modification);GO:0031145(anaphase-promoting complex-dependent catabolic process);GO:0004842(ubiquitin-protein transferase activity);GO:0043025(neuronal cell body);GO:0050775(positive regulation of dendrite morphogenesis);GO:2001224(positive regulation of neuron migration);GO:0005813(centrosome);GO:0016020(membrane);GO:0016021(integral component of membrane)","NA","NA","NA","F-box protein 31 [Source:HGNC Symbol;Acc:HGNC:16510]",{"v":5.868E-3,"d":"0.01"},{"v":0.016233,"d":"0.02"},{"v":0.361485862132693,"d":"0.36"},{"v":-1.46798887103022,"d":"-1.47"},1,1,"down","no"]
[45433,0,"chr12","-",95972662,95996365,"ENST00000541929",20,3846,"MSTRG.3623","HAL","GO:0005737(cytoplasm);GO:0003824(catalytic activity);GO:0016829(lyase activity);GO:0005829(cytosol);GO:0006548(histidine catabolic process);GO:0016841(ammonia-lyase activity);GO:0006547(histidine metabolic process);GO:0019556(histidine catabolic process to glutamate and formamide);GO:0019557(histidine catabolic process to glutamate and formate);GO:0004397(histidine ammonia-lyase activity)","00340(Histidine metabolism)","K01745","EC:4.3.1.3","histidine ammonia-lyase [Source:HGNC Symbol;Acc:HGNC:4806]",{"v":0.824479,"d":"0.82"},0,"inf","inf",1,1,"up","no"]
[172147,0,"chr7","+",18495739,18590354,"ENST00000476135",5,1115,"ENSG00000048052","HDAC9","GO:0005737(cytoplasm);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0004407(histone deacetylase activity);GO:0016787(hydrolase activity);GO:0032041(NAD-dependent histone deacetylase activity (H3-K14 specific));GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0016569(covalent chromatin modification);GO:0005515(protein binding);GO:0006325(chromatin organization);GO:0006954(inflammatory response);GO:0005654(nucleoplasm);GO:0016575(histone deacetylation);GO:0042113(B cell activation);GO:0000118(histone deacetylase complex);GO:0005667(transcription factor complex);GO:0008134(transcription factor binding);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0045892(negative regulation of transcription, DNA-templated);GO:0007507(heart development);GO:0035097(histone methyltransferase complex);GO:0042826(histone deacetylase binding);GO:0032869(cellular response to insulin stimulus);GO:0003714(transcription corepressor activity);GO:0030183(B cell differentiation);GO:0005080(protein kinase C binding);GO:0090050(positive regulation of cell migration involved in sprouting angiogenesis);GO:0070491(repressing transcription factor binding);GO:0033558(protein deacetylase activity);GO:0034983(peptidyl-lysine deacetylation);GO:0070932(histone H3 deacetylation);GO:0070933(histone H4 deacetylation);GO:0048742(regulation of skeletal muscle fiber development);GO:0051153(regulation of striated muscle cell differentiation);GO:0001975(response to amphetamine);GO:0030182(neuron differentiation)","05203(Viral carcinogenesis);05034(Alcoholism);05165(Human papillomavirus infection)","NA","NA","histone deacetylase 9 [Source:HGNC Symbol;Acc:HGNC:14065]",{"v":0.045178,"d":"0.05"},0,"inf","inf",1,1,"up","no"]
[84070,0,"chr17","-",44091293,44093505,"ENST00000587776",6,917,"MSTRG.6884","HDAC5","GO:0051091(positive regulation of sequence-specific DNA binding transcription factor activity);GO:0010832(negative regulation of myotube differentiation);GO:0090051(negative regulation of cell migration involved in sprouting angiogenesis);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0005737(cytoplasm);GO:0005634(nucleus);GO:0016607(nuclear speck);GO:0005794(Golgi apparatus);GO:0046872(metal ion binding);GO:0005829(cytosol);GO:0004407(histone deacetylase activity);GO:0016787(hydrolase activity);GO:0032041(NAD-dependent histone deacetylase activity (H3-K14 specific));GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0016569(covalent chromatin modification);GO:0070932(histone H3 deacetylation);GO:0006476(protein deacetylation);GO:0005515(protein binding);GO:0006325(chromatin organization);GO:0006954(inflammatory response);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0001047(core promoter binding);GO:0005654(nucleoplasm);GO:0016575(histone deacetylation);GO:0042113(B cell activation);GO:0000118(histone deacetylase complex);GO:0040029(regulation of gene expression, epigenetic);GO:0045892(negative regulation of transcription, DNA-templated);GO:0044212(transcription regulatory region DNA binding);GO:0008134(transcription factor binding);GO:0033558(protein deacetylase activity);GO:0042826(histone deacetylase binding);GO:0032869(cellular response to insulin stimulus);GO:0006338(chromatin remodeling);GO:0030183(B cell differentiation);GO:0005080(protein kinase C binding);GO:0043393(regulation of protein binding);GO:0070491(repressing transcription factor binding);GO:0001025(RNA polymerase III transcription factor binding);GO:0010830(regulation of myotube differentiation);GO:0006342(chromatin silencing);GO:0003682(chromatin binding);GO:0014823(response to activity);GO:0030182(neuron differentiation);GO:0042220(response to cocaine);GO:0042493(response to drug);GO:0071222(cellular response to lipopolysaccharide);GO:0043234(protein complex)","04371(Apelin signaling pathway);05203(Viral carcinogenesis);05034(Alcoholism);05169(Epstein-Barr virus infection);05165(Human papillomavirus infection)","NA","NA","histone deacetylase 5 [Source:HGNC Symbol;Acc:HGNC:14068]",0,0,1,0,1,1,"no","no"]
[169200,0,"chr6","+",131628442,131676797,"ENST00000427707",12,1536,"ENSG00000154269","ENPP3","GO:0048471(perinuclear region of cytoplasm);GO:0003676(nucleic acid binding);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0046872(metal ion binding);GO:0016787(hydrolase activity);GO:0003824(catalytic activity);GO:0008152(metabolic process);GO:0090305(nucleic acid phosphodiester bond hydrolysis);GO:0005576(extracellular region);GO:0006955(immune response);GO:0005044(scavenger receptor activity);GO:0006898(receptor-mediated endocytosis);GO:0004551(nucleotide diphosphatase activity);GO:0035529(NADH pyrophosphatase activity);GO:0030247(polysaccharide binding);GO:0070062(extracellular exosome);GO:0005887(integral component of plasma membrane);GO:0004528(phosphodiesterase I activity);GO:0047429(nucleoside-triphosphate diphosphatase activity);GO:0006796(phosphate-containing compound metabolic process);GO:0009143(nucleoside triphosphate catabolic process)","00500(Starch and sucrose metabolism);00230(Purine metabolism);00240(Pyrimidine metabolism);00740(Riboflavin metabolism);00760(Nicotinate and nicotinamide metabolism);00770(Pantothenate and CoA biosynthesis)","NA","NA","ectonucleotide pyrophosphatase/phosphodiesterase 3 [Source:HGNC Symbol;Acc:HGNC:3358]",{"v":0.025711,"d":"0.03"},0,"inf","inf",1,1,"up","no"]
[118974,0,"chr2","+",218125705,218134846,"ENST00000449014",4,262,"MSTRG.9411","CXCR2","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0004930(G-protein coupled receptor activity);GO:0007186(G-protein coupled receptor signaling pathway);GO:0004871(signal transducer activity);GO:0007165(signal transduction);GO:0006935(chemotaxis);GO:0070098(chemokine-mediated signaling pathway);GO:0016494(C-X-C chemokine receptor activity);GO:0019959(interleukin-8 binding);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0005887(integral component of plasma membrane);GO:0030593(neutrophil chemotaxis);GO:0005622(intracellular);GO:0043312(neutrophil degranulation);GO:0008284(positive regulation of cell proliferation);GO:0006954(inflammatory response);GO:0009986(cell surface);GO:0030667(secretory granule membrane);GO:0002407(dendritic cell chemotaxis);GO:0006968(cellular defense response);GO:0031623(receptor internalization);GO:0007166(cell surface receptor signaling pathway);GO:0007200(phospholipase C-activating G-protein coupled receptor signaling pathway);GO:0042629(mast cell granule);GO:0042119(neutrophil activation);GO:0004918(interleukin-8 receptor activity);GO:0038112(interleukin-8-mediated signaling pathway)","04072(Phospholipase D signaling pathway);04060(Cytokine-cytokine receptor interaction);04144(Endocytosis);04062(Chemokine signaling pathway);05120(Epithelial cell signaling in Helicobacter pylori infection)","NA","NA","C-X-C motif chemokine receptor 2 [Source:HGNC Symbol;Acc:HGNC:6027]",{"v":0.715884,"d":"0.72"},{"v":1.596298,"d":"1.60"},{"v":0.448465136208903,"d":"0.45"},{"v":-1.15693226085443,"d":"-1.16"},1,1,"down","no"]
[97810,0,"chr19","-",15468645,15479501,"ENST00000292609",4,2758,"ENSG00000161031","PGLYRP2","GO:0016020(membrane);GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0016787(hydrolase activity);GO:0005576(extracellular region);GO:0002376(immune system process);GO:0045087(innate immune response);GO:0070062(extracellular exosome);GO:0005622(intracellular);GO:0002221(pattern recognition receptor signaling pathway);GO:0050830(defense response to Gram-positive bacterium);GO:0009253(peptidoglycan catabolic process);GO:0019730(antimicrobial humoral response);GO:0042834(peptidoglycan binding);GO:0008745(N-acetylmuramoyl-L-alanine amidase activity);GO:0016019(peptidoglycan receptor activity);GO:0016045(detection of bacterium);GO:0001519(peptide amidation);GO:0032689(negative regulation of interferon-gamma production);GO:0032827(negative regulation of natural killer cell differentiation involved in immune response);GO:0044117(growth of symbiont in host);GO:0050727(regulation of inflammatory response)","NA","NA","NA","peptidoglycan recognition protein 2 [Source:HGNC Symbol;Acc:HGNC:30013]",{"v":0.097241,"d":"0.10"},{"v":0.031381,"d":"0.03"},{"v":3.09872215671903,"d":"3.10"},{"v":1.63167340316756,"d":"1.63"},1,1,"up","no"]
[176621,0,"chr7","-",99658833,99663582,"ENST00000473347",2,2594,"ENSG00000106258","CYP3A5","GO:0016020(membrane);GO:0046872(metal ion binding);GO:0004497(monooxygenase activity);GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005506(iron ion binding);GO:0016705(oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen);GO:0020037(heme binding);GO:0016712(oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen);GO:0070330(aromatase activity);GO:0043231(intracellular membrane-bounded organelle);GO:0006805(xenobiotic metabolic process);GO:0031090(organelle membrane);GO:0019825(oxygen binding);GO:0008202(steroid metabolic process);GO:0101020(estrogen 16-alpha-hydroxylase activity);GO:0002933(lipid hydroxylation);GO:0042737(drug catabolic process);GO:0070989(oxidative demethylation);GO:0009822(alkaloid catabolic process);GO:0016021(integral component of membrane)","00140(Steroid hormone biosynthesis);00830(Retinol metabolism);00980(Metabolism of xenobiotics by cytochrome P450);00982(Drug metabolism - cytochrome P450);05204(Chemical carcinogenesis)","NA","NA","cytochrome P450 family 3 subfamily A member 5 [Source:HGNC Symbol;Acc:HGNC:2638]",0,{"v":0.071812,"d":"0.07"},"-inf","-inf",1,1,"down","no"]
[157967,0,"chr5","+",127290859,127461222,"ENST00000274473",26,7594,"ENSG00000145794","MEGF10","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0007155(cell adhesion);GO:0005886(plasma membrane);GO:0042995(cell projection);GO:0006898(receptor-mediated endocytosis);GO:0001891(phagocytic cup);GO:0034109(homotypic cell-cell adhesion);GO:0016323(basolateral plasma membrane);GO:0007517(muscle organ development);GO:0006909(phagocytosis);GO:0005112(Notch binding);GO:0043652(engulfment of apoptotic cell);GO:0051451(myoblast migration);GO:1902742(apoptotic process involved in development);GO:0051147(regulation of muscle cell differentiation);GO:0014719(skeletal muscle satellite cell activation);GO:0001849(complement component C1q binding);GO:0005044(scavenger receptor activity);GO:0014816(skeletal muscle satellite cell differentiation);GO:0014841(skeletal muscle satellite cell proliferation);GO:0033002(muscle cell proliferation);GO:0048641(regulation of skeletal muscle tissue development);GO:0055001(muscle cell development);GO:0043654(recognition of apoptotic cell)","NA","NA","NA","multiple EGF like domains 10 [Source:HGNC Symbol;Acc:HGNC:29634]",{"v":0.025206,"d":"0.03"},{"v":0.020787,"d":"0.02"},{"v":1.21258478856978,"d":"1.21"},{"v":0.278085629586249,"d":"0.28"},1,1,"up","no"]
[139646,0,"chr3","-",121795461,121835033,"ENST00000460108",9,988,"ENSG00000173226","IQCB1","GO:0005737(cytoplasm);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0060271(cilium assembly);GO:0005516(calmodulin binding);GO:0005813(centrosome);GO:0005815(microtubule organizing center);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0030030(cell projection organization);GO:0005814(centriole);GO:0097711(ciliary basal body docking);GO:0019899(enzyme binding);GO:0045494(photoreceptor cell maintenance);GO:0048496(maintenance of animal organ identity);GO:0001750(photoreceptor outer segment);GO:0032391(photoreceptor connecting cilium)","NA","NA","NA","IQ motif containing B1 [Source:HGNC Symbol;Acc:HGNC:28949]",{"v":0.141838,"d":"0.14"},{"v":0.102504,"d":"0.10"},{"v":1.38373136658082,"d":"1.38"},{"v":0.468563889709664,"d":"0.47"},1,1,"up","no"]
[83051,0,"chr17","+",40123097,40126860,"ENST00000578826",2,962,"MSTRG.6793","MSL1","GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0016569(covalent chromatin modification);GO:0043984(histone H4-K16 acetylation);GO:0072487(MSL complex)","NA","NA","NA","male specific lethal 1 homolog [Source:HGNC Symbol;Acc:HGNC:27905]",0,{"v":0.256754,"d":"0.26"},"-inf","-inf",1,1,"down","no"]
[5351,0,"chr1","+",44739820,44767767,"ENST00000372224",21,2879,"MSTRG.512","KIF2C","GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0003777(microtubule motor activity);GO:0008017(microtubule binding);GO:0003774(motor activity);GO:0007018(microtubule-based movement);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0051301(cell division);GO:0005694(chromosome);GO:0005813(centrosome);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0007049(cell cycle);GO:0005874(microtubule);GO:0007059(chromosome segregation);GO:0000775(chromosome, centromeric region);GO:0000776(kinetochore);GO:0000777(condensed chromosome kinetochore);GO:0006890(retrograde vesicle-mediated transport, Golgi to ER);GO:0016887(ATPase activity);GO:0007062(sister chromatid cohesion);GO:0019886(antigen processing and presentation of exogenous peptide antigen via MHC class II);GO:0008283(cell proliferation);GO:0000278(mitotic cell cycle);GO:0051310(metaphase plate congression);GO:0051315(attachment of mitotic spindle microtubules to kinetochore);GO:0005871(kinesin complex);GO:0005881(cytoplasmic microtubule);GO:0019237(centromeric DNA binding);GO:0007080(mitotic metaphase plate congression);GO:0051983(regulation of chromosome segregation);GO:0051010(microtubule plus-end binding);GO:0015630(microtubule cytoskeleton);GO:0035371(microtubule plus-end);GO:0030951(establishment or maintenance of microtubule cytoskeleton polarity);GO:0007019(microtubule depolymerization)","NA","NA","NA","kinesin family member 2C [Source:HGNC Symbol;Acc:HGNC:6393]",{"v":0.691011,"d":"0.69"},0,"inf","inf",1,1,"up","no"]
[197336,0,"chrX","+",51893649,51902354,"ENST00000494718",6,5418,"ENSG00000179222","MAGED1","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0006355(regulation of transcription, DNA-templated);GO:0042981(regulation of apoptotic process);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0048511(rhythmic process);GO:0042802(identical protein binding);GO:0032922(circadian regulation of gene expression);GO:0043234(protein complex);GO:0000785(chromatin);GO:0050680(negative regulation of epithelial cell proliferation);GO:0003713(transcription coactivator activity);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0042752(regulation of circadian rhythm);GO:0043406(positive regulation of MAP kinase activity);GO:0045892(negative regulation of transcription, DNA-templated);GO:0045893(positive regulation of transcription, DNA-templated);GO:0090190(positive regulation of branching involved in ureteric bud morphogenesis);GO:2001235(positive regulation of apoptotic signaling pathway)","04722(Neurotrophin signaling pathway)","NA","NA","MAGE family member D1 [Source:HGNC Symbol;Acc:HGNC:6813]",{"v":0.110227,"d":"0.11"},{"v":0.049519,"d":"0.05"},{"v":2.22595367434722,"d":"2.23"},{"v":1.15442356820324,"d":"1.15"},1,1,"up","no"]
[62615,0,"chr15","-",51919073,51930627,"ENST00000557871",9,1041,"MSTRG.5087","AC090971.3","NA","NA","NA","NA","NA",{"v":0.161864,"d":"0.16"},{"v":0.161145,"d":"0.16"},{"v":1.00446182009991,"d":"1.00"},{"v":0.00642272783491907,"d":"0.01"},1,1,"up","no"]
[17799,0,"chr1","+",247920252,247921956,"ENST00000641945",2,1226,"ENSG00000177462","OR2T8","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0004930(G-protein coupled receptor activity);GO:0007186(G-protein coupled receptor signaling pathway);GO:0005886(plasma membrane);GO:0004871(signal transducer activity);GO:0007165(signal transduction);GO:0004984(olfactory receptor activity);GO:0007608(sensory perception of smell);GO:0050896(response to stimulus);GO:0050911(detection of chemical stimulus involved in sensory perception of smell)","04740(Olfactory transduction)","K04257","NA","olfactory receptor family 2 subfamily T member 8 [Source:HGNC Symbol;Acc:HGNC:15020]",0,0,1,0,1,1,"no","no"]
[78424,0,"chr17","+",6651718,6653473,"ENST00000542475",1,1756,"MSTRG.6371","C17orf100","NA","NA","NA","NA","chromosome 17 open reading frame 100 [Source:HGNC Symbol;Acc:HGNC:34494]",{"v":0.367269,"d":"0.37"},0,"inf","inf",1,1,"up","no"]
[161772,0,"chr5","-",178153222,178153884,"ENST00000510363",2,566,"MSTRG.12587","NHP2","GO:0003723(RNA binding);GO:0005634(nucleus);GO:0030529(intracellular ribonucleoprotein complex);GO:0005515(protein binding);GO:0005730(nucleolus);GO:0042254(ribosome biogenesis);GO:0006364(rRNA processing);GO:0005654(nucleoplasm);GO:0000784(nuclear chromosome, telomeric region);GO:0005732(small nucleolar ribonucleoprotein complex);GO:0070034(telomerase RNA binding);GO:0007004(telomere maintenance via telomerase);GO:0005697(telomerase holoenzyme complex);GO:0015030(Cajal body);GO:0006412(translation);GO:0034513(box H/ACA snoRNA binding);GO:0031118(rRNA pseudouridine synthesis);GO:0031120(snRNA pseudouridine synthesis);GO:1904874(positive regulation of telomerase RNA localization to Cajal body);GO:0031429(box H/ACA snoRNP complex);GO:0072589(box H/ACA scaRNP complex);GO:0090661(box H/ACA telomerase RNP complex);GO:0000470(maturation of LSU-rRNA);GO:0030515(snoRNA binding);GO:0000469(cleavage involved in rRNA processing)","03008(Ribosome biogenesis in eukaryotes)","NA","NA","NHP2 ribonucleoprotein [Source:HGNC Symbol;Acc:HGNC:14377]",{"v":1.01E-4,"d":"0.00"},{"v":0.015227,"d":"0.02"},{"v":0.00663295462008275,"d":"0.01"},{"v":-7.23613262907257,"d":"-7.24"},1,1,"down","no"]
[132593,"p","chr22",".",50541776,50541980,"MSTRG.10607.1",1,205,"MSTRG.10607","U62317.2","NA","NA","NA","NA","NA",{"v":6.380539,"d":"6.38"},0,"inf","inf",1,1,"up","no"]
[109180,0,"chr2","-",42767120,42792574,"ENST00000402698",9,1522,"ENSG00000162882","HAAO","GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0005829(cytosol);GO:0005506(iron ion binding);GO:0005515(protein binding);GO:0009435(NAD biosynthetic process);GO:0019363(pyridine nucleotide biosynthetic process);GO:0051213(dioxygenase activity);GO:0070062(extracellular exosome);GO:0000334(3-hydroxyanthranilate 3,4-dioxygenase activity);GO:0009055(electron carrier activity);GO:0006569(tryptophan catabolic process);GO:0008198(ferrous iron binding);GO:0010043(response to zinc ion);GO:0019805(quinolinate biosynthetic process);GO:0046686(response to cadmium ion);GO:0070050(neuron cellular homeostasis)","00380(Tryptophan metabolism)","NA","NA","3-hydroxyanthranilate 3,4-dioxygenase [Source:HGNC Symbol;Acc:HGNC:4796]",{"v":1.044233,"d":"1.04"},0,"inf","inf",1,1,"up","no"]
[63877,0,"chr15","+",67166019,67190762,"ENST00000537194",7,1147,"MSTRG.5211","SMAD3","GO:0006355(regulation of transcription, DNA-templated);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0005622(intracellular);GO:0007179(transforming growth factor beta receptor signaling pathway);GO:0005667(transcription factor complex);GO:0010628(positive regulation of gene expression);GO:0045599(negative regulation of fat cell differentiation);GO:0010718(positive regulation of epithelial to mesenchymal transition);GO:0006919(activation of cysteine-type endopeptidase activity involved in apoptotic process);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0005737(cytoplasm);GO:0005634(nucleus);GO:0045930(negative regulation of mitotic cell cycle);GO:0046872(metal ion binding);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0008270(zinc ion binding);GO:0005515(protein binding);GO:0000977(RNA polymerase II regulatory region sequence-specific DNA binding);GO:0003682(chromatin binding);GO:0003690(double-stranded DNA binding);GO:0005518(collagen binding);GO:0008013(beta-catenin binding);GO:0008134(transcription factor binding);GO:0019899(enzyme binding);GO:0031490(chromatin DNA binding);GO:0042803(protein homodimerization activity);GO:0043565(sequence-specific DNA binding);GO:0046332(SMAD binding);GO:0046982(protein heterodimerization activity);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0001501(skeletal system development);GO:0001649(osteoblast differentiation);GO:0001657(ureteric bud development);GO:0001701(in utero embryonic development);GO:0001707(mesoderm formation);GO:0001756(somitogenesis);GO:0001889(liver development);GO:0001947(heart looping);GO:0002076(osteoblast development);GO:0002520(immune system development);GO:0007183(SMAD protein complex assembly);GO:0007369(gastrulation);GO:0007492(endoderm development);GO:0008285(negative regulation of cell proliferation);GO:0009880(embryonic pattern specification);GO:0010694(positive regulation of alkaline phosphatase activity);GO:0016202(regulation of striated muscle tissue development);GO:0017015(regulation of transforming growth factor beta receptor signaling pathway);GO:0023019(signal transduction involved in regulation of gene expression);GO:0030335(positive regulation of cell migration);GO:0030501(positive regulation of bone mineralization);GO:0030878(thyroid gland development);GO:0032332(positive regulation of chondrocyte differentiation);GO:0032731(positive regulation of interleukin-1 beta production);GO:0032916(positive regulation of transforming growth factor beta3 production);GO:0033689(negative regulation of osteoblast proliferation);GO:0035413(positive regulation of catenin import into nucleus);GO:0042110(T cell activation);GO:0042177(negative regulation of protein catabolic process);GO:0043066(negative regulation of apoptotic process);GO:0045429(positive regulation of nitric oxide biosynthetic process);GO:0045668(negative regulation of osteoblast differentiation);GO:0045893(positive regulation of transcription, DNA-templated);GO:0048340(paraxial mesoderm morphogenesis);GO:0048589(developmental growth);GO:0048617(embryonic foregut morphogenesis);GO:0048701(embryonic cranial skeleton morphogenesis);GO:0050678(regulation of epithelial cell proliferation);GO:0050728(negative regulation of inflammatory response);GO:0050776(regulation of immune response);GO:0050821(protein stabilization);GO:0050927(positive regulation of positive chemotaxis);GO:0051098(regulation of binding);GO:0051496(positive regulation of stress fiber assembly);GO:0051894(positive regulation of focal adhesion assembly);GO:0060039(pericardium development);GO:0060070(canonical Wnt signaling pathway);GO:0060290(transdifferentiation);GO:0060395(SMAD protein signal transduction);GO:0061045(negative regulation of wound healing);GO:0061767(negative regulation of lung blood pressure);GO:0070306(lens fiber cell differentiation);GO:0097296(activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway);GO:1903243(negative regulation of cardiac muscle hypertrophy in response to stress);GO:0005886(plasma membrane);GO:0043234(protein complex);GO:0042802(identical protein binding);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:0005637(nuclear inner membrane);GO:0019901(protein kinase binding);GO:0016579(protein deubiquitination);GO:0019902(phosphatase binding);GO:0043130(ubiquitin binding);GO:0043425(bHLH transcription factor binding);GO:0070412(R-SMAD binding);GO:0000790(nuclear chromatin);GO:0044212(transcription regulatory region DNA binding);GO:0070410(co-SMAD binding);GO:0001102(RNA polymerase II activating transcription factor binding);GO:1902895(positive regulation of pri-miRNA transcription from RNA polymerase II promoter);GO:0043235(receptor complex);GO:0031625(ubiquitin protein ligase binding);GO:0030512(negative regulation of transforming growth factor beta receptor signaling pathway);GO:0030618(transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity);GO:0097191(extrinsic apoptotic signaling pathway);GO:0000987(core promoter proximal region sequence-specific DNA binding);GO:0030308(negative regulation of cell growth);GO:0006955(immune response);GO:0000983(transcription factor activity, RNA polymerase II core promoter sequence-specific);GO:0035326(enhancer binding);GO:0032924(activin receptor signaling pathway);GO:0042993(positive regulation of transcription factor import into nucleus);GO:0007050(cell cycle arrest);GO:0019049(evasion or tolerance of host defenses by virus);GO:0045216(cell-cell junction organization);GO:1901203(positive regulation of extracellular matrix assembly);GO:0042060(wound healing);GO:0071560(cellular response to transforming growth factor beta stimulus);GO:0001666(response to hypoxia);GO:0070878(primary miRNA binding);GO:0051481(negative regulation of cytosolic calcium ion concentration);GO:0071141(SMAD protein complex);GO:0005160(transforming growth factor beta receptor binding);GO:0032909(regulation of transforming growth factor beta2 production);GO:0035259(glucocorticoid receptor binding);GO:0000988(transcription factor activity, protein binding);GO:0017151(DEAD/H-box RNA helicase binding);GO:0031962(mineralocorticoid receptor binding);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0006810(transport);GO:0031053(primary miRNA processing);GO:0038092(nodal signaling pathway);GO:0071144(SMAD2-SMAD3 protein complex)","04310(Wnt signaling pathway);04350(TGF-beta signaling pathway);04390(Hippo signaling pathway);04371(Apelin signaling pathway);04068(FoxO signaling pathway);04144(Endocytosis);04110(Cell cycle);04218(Cellular senescence);04520(Adherens junction);04550(Signaling pathways regulating pluripotency of stem cells);04659(Th17 cell differentiation);04926(Relaxin signaling pathway);05200(Pathways in cancer);05210(Colorectal cancer);05212(Pancreatic cancer);05225(Hepatocellular carcinoma);05226(Gastric cancer);05220(Chronic myeloid leukemia);05321(Inflammatiory bowel disease (IBD));04933(AGE-RAGE signaling pathway in diabetic complications);05166(HTLV-I infection);05161(Hepatitis B);05142(Chagas disease (American trypanosomiasis))","K04500","NA","SMAD family member 3 [Source:HGNC Symbol;Acc:HGNC:6769]",0,0,1,0,1,1,"no","no"]
[132295,0,"chr22","+",46335745,46357184,"ENST00000381019",10,1381,"ENSG00000100416","TRMU","GO:0008168(methyltransferase activity);GO:0016740(transferase activity);GO:0008033(tRNA processing);GO:0032259(methylation);GO:0003723(RNA binding);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0005654(nucleoplasm);GO:0005739(mitochondrion);GO:0000049(tRNA binding);GO:0016783(sulfurtransferase activity);GO:0002143(tRNA wobble position uridine thiolation);GO:0070903(mitochondrial tRNA thio-modification)","NA","NA","NA","tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase [Source:HGNC Symbol;Acc:HGNC:25481]",0,0,1,0,1,1,"no","no"]
[88777,0,"chr17","+",78202509,78207202,"ENST00000587750",4,541,"ENSG00000183077","AFMID","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016787(hydrolase activity);GO:0008152(metabolic process);GO:0005829(cytosol);GO:0019441(tryptophan catabolic process to kynurenine);GO:0006569(tryptophan catabolic process);GO:0004061(arylformamidase activity)","00630(Glyoxylate and dicarboxylate metabolism);00380(Tryptophan metabolism)","NA","NA","arylformamidase [Source:HGNC Symbol;Acc:HGNC:20910]",{"v":0.536238,"d":"0.54"},{"v":0.390659,"d":"0.39"},{"v":1.37264980456101,"d":"1.37"},{"v":0.456963606792264,"d":"0.46"},1,1,"up","no"]
[140227,0,"chr3","-",128486148,128490648,"ENST00000492608",3,844,"ENSG00000179348","GATA2","GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0005634(nucleus);GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0005654(nucleoplasm);GO:0006355(regulation of transcription, DNA-templated);GO:0006366(transcription from RNA polymerase II promoter);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0043565(sequence-specific DNA binding);GO:0005515(protein binding);GO:0030097(hemopoiesis);GO:1902036(regulation of hematopoietic stem cell differentiation);GO:0005667(transcription factor complex);GO:0000977(RNA polymerase II regulatory region sequence-specific DNA binding);GO:0001228(transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding);GO:0006909(phagocytosis);GO:0050766(positive regulation of phagocytosis);GO:0045599(negative regulation of fat cell differentiation);GO:0070345(negative regulation of fat cell proliferation);GO:0007596(blood coagulation);GO:0003682(chromatin binding);GO:0008134(transcription factor binding);GO:0045766(positive regulation of angiogenesis);GO:0001085(RNA polymerase II transcription factor binding);GO:0070742(C2H2 zinc finger domain binding);GO:0035854(eosinophil fate commitment);GO:0000979(RNA polymerase II core promoter sequence-specific DNA binding);GO:0000980(RNA polymerase II distal enhancer sequence-specific DNA binding);GO:0001077(transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0001158(enhancer sequence-specific DNA binding);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0001655(urogenital system development);GO:0001709(cell fate determination);GO:0001764(neuron migration);GO:0001892(embryonic placenta development);GO:0007204(positive regulation of cytosolic calcium ion concentration);GO:0010725(regulation of primitive erythrocyte differentiation);GO:0021514(ventral spinal cord interneuron differentiation);GO:0021533(cell differentiation in hindbrain);GO:0021902(commitment of neuronal cell to specific neuron type in forebrain);GO:0021954(central nervous system neuron development);GO:0021983(pituitary gland development);GO:0030154(cell differentiation);GO:0030182(neuron differentiation);GO:0033993(response to lipid);GO:0035019(somatic stem cell population maintenance);GO:0035065(regulation of histone acetylation);GO:0042472(inner ear morphogenesis);GO:0043306(positive regulation of mast cell degranulation);GO:0045638(negative regulation of myeloid cell differentiation);GO:0045648(positive regulation of erythrocyte differentiation);GO:0045650(negative regulation of macrophage differentiation);GO:0045654(positive regulation of megakaryocyte differentiation);GO:0045666(positive regulation of neuron differentiation);GO:0045746(negative regulation of Notch signaling pathway);GO:0048469(cell maturation);GO:0048663(neuron fate commitment);GO:0048873(homeostasis of number of cells within a tissue);GO:0060100(positive regulation of phagocytosis, engulfment);GO:0060216(definitive hemopoiesis);GO:0060872(semicircular canal development);GO:0090102(cochlea development);GO:0097154(GABAergic neuron differentiation);GO:2000178(negative regulation of neural precursor cell proliferation);GO:2000977(regulation of forebrain neuron differentiation);GO:0043234(protein complex)","NA","NA","NA","GATA binding protein 2 [Source:HGNC Symbol;Acc:HGNC:4171]",{"v":0.041414,"d":"0.04"},0,"inf","inf",1,1,"up","no"]
[78515,0,"chr17","+",7012646,7014532,"ENST00000552176",2,1485,"MSTRG.6383","RNASEK","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0016787(hydrolase activity);GO:0090305(nucleic acid phosphodiester bond hydrolysis);GO:0004519(endonuclease activity);GO:0090502(RNA phosphodiester bond hydrolysis, endonucleolytic);GO:0004518(nuclease activity);GO:0004521(endoribonuclease activity);GO:0009303(rRNA transcription);GO:0005575(cellular_component)","NA","NA","NA","ribonuclease K [Source:HGNC Symbol;Acc:HGNC:33911]",{"v":0.401308,"d":"0.40"},{"v":0.313373,"d":"0.31"},{"v":1.28060809323075,"d":"1.28"},{"v":0.356829032698182,"d":"0.36"},1,1,"up","no"]
[158803,0,"chr5","+",138424135,138425857,"ENST00000505756",2,654,"MSTRG.12353","KDM3B","GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0016569(covalent chromatin modification);GO:0051213(dioxygenase activity);GO:0098869(cellular oxidant detoxification);GO:0005654(nucleoplasm);GO:0000976(transcription regulatory region sequence-specific DNA binding);GO:0032452(histone demethylase activity);GO:0000785(chromatin);GO:0031490(chromatin DNA binding);GO:0032454(histone demethylase activity (H3-K9 specific));GO:0033169(histone H3-K9 demethylation);GO:0016209(antioxidant activity);GO:0072718(response to cisplatin)","NA","NA","NA","lysine demethylase 3B [Source:HGNC Symbol;Acc:HGNC:1337]",{"v":1.030147,"d":"1.03"},{"v":0.072973,"d":"0.07"},{"v":14.1168240308059,"d":"14.12"},{"v":3.81934364593369,"d":"3.82"},1,1,"up","no"]
[48047,0,"chr12","+",123364953,123366113,"ENST00000543072",2,752,"MSTRG.3835","AC137767.1","NA","NA","NA","NA","NA",0,0,1,0,1,1,"no","no"]
[33753,0,"chr11","-",83486155,83724956,"ENST00000530800",5,566,"ENSG00000150672","DLG2","GO:0016020(membrane);GO:0005886(plasma membrane);GO:0042995(cell projection);GO:0005515(protein binding);GO:0030054(cell junction);GO:0045202(synapse);GO:0045211(postsynaptic membrane);GO:0030424(axon);GO:0005829(cytosol);GO:0007399(nervous system development);GO:0014069(postsynaptic density);GO:0010923(negative regulation of phosphatase activity);GO:0046037(GMP metabolic process);GO:0046710(GDP metabolic process);GO:0007268(chemical synaptic transmission);GO:0004385(guanylate kinase activity);GO:0008076(voltage-gated potassium channel complex);GO:0019900(kinase binding);GO:0008328(ionotropic glutamate receptor complex);GO:0035255(ionotropic glutamate receptor binding);GO:0097120(receptor localization to synapse);GO:0044224(juxtaparanode region of axon);GO:0043113(receptor clustering);GO:0019233(sensory perception of pain)","04390(Hippo signaling pathway);04530(Tight junction);05165(Human papillomavirus infection)","NA","NA","discs large MAGUK scaffold protein 2 [Source:HGNC Symbol;Acc:HGNC:2901]",0,{"v":0.060158,"d":"0.06"},"-inf","-inf",1,1,"down","no"]
[113401,0,"chr2","+",110279606,110285681,"ENST00000633535",3,357,"MSTRG.9037","AC140479.6","NA","NA","NA","NA","NA",0,0,1,0,1,1,"no","no"]
[10478,0,"chr1","-",149928651,149936869,"ENST00000482025",15,2834,"MSTRG.905","MTMR11","GO:0070062(extracellular exosome)","NA","NA","NA","myotubularin related protein 11 [Source:HGNC Symbol;Acc:HGNC:24307]",{"v":1.387E-3,"d":"0.00"},{"v":0.025949,"d":"0.03"},{"v":0.0534510000385371,"d":"0.05"},{"v":-4.22563924955316,"d":"-4.23"},1,1,"down","no"]
[65522,0,"chr15","+",80075161,80138392,"ENST00000616533",7,1653,"MSTRG.5351","ZFAND6","GO:0006810(transport);GO:0005737(cytoplasm);GO:0015031(protein transport);GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0006915(apoptotic process);GO:0003674(molecular_function);GO:0005575(cellular_component);GO:0071356(cellular response to tumor necrosis factor);GO:0043066(negative regulation of apoptotic process);GO:0006625(protein targeting to peroxisome);GO:0043122(regulation of I-kappaB kinase/NF-kappaB signaling);GO:0031593(polyubiquitin binding)","NA","NA","NA","zinc finger AN1-type containing 6 [Source:HGNC Symbol;Acc:HGNC:30164]",0,{"v":0.042423,"d":"0.04"},"-inf","-inf",1,1,"down","no"]
[74356,0,"chr16","+",67192207,67196008,"ENST00000568839",6,944,"MSTRG.6004","E2F4","GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0046983(protein dimerization activity);GO:0006355(regulation of transcription, DNA-templated);GO:0006366(transcription from RNA polymerase II promoter);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0005515(protein binding);GO:0007049(cell cycle);GO:0005667(transcription factor complex);GO:0000278(mitotic cell cycle);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:0006977(DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0030030(cell projection organization);GO:0044458(motile cilium assembly);GO:0098534(centriole assembly);GO:1903251(multi-ciliated epithelial cell differentiation);GO:0019904(protein domain specific binding);GO:0008134(transcription factor binding);GO:0000790(nuclear chromatin);GO:0001077(transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:1990841(promoter-specific chromatin binding);GO:0001228(transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding);GO:0000083(regulation of transcription involved in G1/S transition of mitotic cell cycle);GO:0002064(epithelial cell development);GO:0006884(cell volume homeostasis);GO:0008015(blood circulation);GO:0008361(regulation of cell size);GO:0009887(animal organ morphogenesis);GO:0042127(regulation of cell proliferation);GO:0060271(cilium assembly)","04350(TGF-beta signaling pathway);04110(Cell cycle);04218(Cellular senescence)","NA","NA","E2F transcription factor 4 [Source:HGNC Symbol;Acc:HGNC:3118]",0,{"v":0.019382,"d":"0.02"},"-inf","-inf",1,1,"down","no"]
[15159,0,"chr1","-",204528845,204529692,"ENST00000432698",1,848,"ENSG00000236779","AL512306.1","NA","NA","NA","NA","NA",0,{"v":0.053802,"d":"0.05"},"-inf","-inf",1,1,"down","no"]
[171574,0,"chr7","+",5602872,5606654,"ENST00000473330",4,2215,"ENSG00000075618","FSCN1","GO:0003723(RNA binding);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0007015(actin filament organization);GO:0051015(actin filament binding);GO:0003779(actin binding);GO:0030036(actin cytoskeleton organization);GO:0005856(cytoskeleton);GO:0042995(cell projection);GO:0005515(protein binding);GO:0030054(cell junction);GO:0016477(cell migration);GO:0030674(protein binding, bridging);GO:0045296(cadherin binding);GO:0030027(lamellipodium);GO:0030175(filopodium);GO:0030426(growth cone);GO:0070062(extracellular exosome);GO:0032956(regulation of actin cytoskeleton organization);GO:0002102(podosome);GO:0001725(stress fiber);GO:0071437(invadopodium);GO:0009653(anatomical structure morphogenesis);GO:0005902(microvillus);GO:0031941(filamentous actin);GO:0001726(ruffle);GO:0051017(actin filament bundle assembly);GO:0015629(actin cytoskeleton);GO:0008144(drug binding);GO:0051491(positive regulation of filopodium assembly);GO:0008283(cell proliferation);GO:0007043(cell-cell junction assembly);GO:0005911(cell-cell junction);GO:0032534(regulation of microvillus assembly);GO:0010592(positive regulation of lamellipodium assembly);GO:0030035(microspike assembly);GO:0048870(cell motility);GO:0090091(positive regulation of extracellular matrix disassembly);GO:0071803(positive regulation of podosome assembly);GO:0031253(cell projection membrane);GO:0035089(establishment of apical/basal cell polarity);GO:0043209(myelin sheath);GO:0044393(microspike)","05206(MicroRNAs in cancer)","NA","NA","fascin actin-bundling protein 1 [Source:HGNC Symbol;Acc:HGNC:11148]",{"v":0.025766,"d":"0.03"},{"v":0.019103,"d":"0.02"},{"v":1.34879338323824,"d":"1.35"},{"v":0.431669363995836,"d":"0.43"},1,1,"up","no"]
[121750,0,"chr20","+",4148831,4181976,"ENST00000484515",5,900,"MSTRG.9581","SMOX","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0043231(intracellular membrane-bounded organelle);GO:0005654(nucleoplasm);GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0031965(nuclear membrane);GO:0005829(cytosol);GO:0006596(polyamine biosynthetic process);GO:0046592(polyamine oxidase activity);GO:0052901(spermine:oxygen oxidoreductase (spermidine-forming) activity);GO:0046208(spermine catabolic process);GO:0052894(norspermine:oxygen oxidoreductase activity);GO:0052895(N1-acetylspermine:oxygen oxidoreductase (N1-acetylspermidine-forming) activity);GO:0006598(polyamine catabolic process)","00330(Arginine and proline metabolism);00410(beta-Alanine metabolism)","NA","NA","spermine oxidase [Source:HGNC Symbol;Acc:HGNC:15862]",0,{"v":0.090305,"d":"0.09"},"-inf","-inf",1,1,"down","no"]
[136762,0,"chr3","-",50559599,50567625,"ENST00000484982",5,565,"ENSG00000088543","C3orf18","GO:0016020(membrane);GO:0016021(integral component of membrane)","NA","NA","NA","chromosome 3 open reading frame 18 [Source:HGNC Symbol;Acc:HGNC:24837]",{"v":0.181597,"d":"0.18"},0,"inf","inf",1,1,"up","no"]
[16708,0,"chr1","-",228107785,228108573,"ENST00000497758",4,470,"ENSG00000162910","MRPL55","GO:0006412(translation);GO:0030529(intracellular ribonucleoprotein complex);GO:0003735(structural constituent of ribosome);GO:0005840(ribosome);GO:0005739(mitochondrion);GO:0005762(mitochondrial large ribosomal subunit);GO:0005743(mitochondrial inner membrane);GO:0070125(mitochondrial translational elongation);GO:0070126(mitochondrial translational termination)","NA","NA","NA","mitochondrial ribosomal protein L55 [Source:HGNC Symbol;Acc:HGNC:16686]",0,0,1,0,1,1,"no","no"]
[172549,0,"chr7","+",26538378,26541048,"ENST00000623092",1,2671,"ENSG00000280255","AC004947.2","NA","NA","NA","NA","NA",{"v":0.014754,"d":"0.01"},{"v":0.017081,"d":"0.02"},{"v":0.863766758386511,"d":"0.86"},{"v":-0.211286298640794,"d":"-0.21"},1,1,"down","no"]
[137023,0,"chr3","+",52388883,52392556,"ENST00000480649",5,579,"MSTRG.10980","DNAH1","GO:0005737(cytoplasm);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0003777(microtubule motor activity);GO:0005856(cytoskeleton);GO:0042995(cell projection);GO:0005874(microtubule);GO:0003774(motor activity);GO:0007018(microtubule-based movement);GO:0016887(ATPase activity);GO:0030286(dynein complex);GO:0003341(cilium movement);GO:0003351(epithelial cilium movement);GO:0030317(flagellated sperm motility);GO:0060294(cilium movement involved in cell motility);GO:0005858(axonemal dynein complex);GO:0036126(sperm flagellum);GO:0005929(cilium);GO:0051959(dynein light intermediate chain binding);GO:0045503(dynein light chain binding);GO:0045505(dynein intermediate chain binding);GO:0060285(cilium-dependent cell motility);GO:0008569(ATP-dependent microtubule motor activity, minus-end-directed);GO:0036159(inner dynein arm assembly);GO:0036156(inner dynein arm)","05016(Huntington's disease)","NA","NA","dynein axonemal heavy chain 1 [Source:HGNC Symbol;Acc:HGNC:2940]",{"v":0.128063,"d":"0.13"},{"v":0.13084,"d":"0.13"},{"v":0.97877560379089,"d":"0.98"},{"v":-0.0309499525306792,"d":"-0.03"},1,1,"down","no"]
[188238,0,"chr8","+",144084793,144086183,"ENST00000530796",4,936,"MSTRG.14626","GPAA1","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0042765(GPI-anchor transamidase complex);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0006506(GPI anchor biosynthetic process);GO:0005515(protein binding);GO:0015631(tubulin binding);GO:0006461(protein complex assembly);GO:0003923(GPI-anchor transamidase activity);GO:0034235(GPI anchor binding);GO:0006621(protein retention in ER lumen);GO:0016255(attachment of GPI anchor to protein)","00563(Glycosylphosphatidylinositol(GPI)-anchor biosynthesis)","NA","NA","glycosylphosphatidylinositol anchor attachment 1 [Source:HGNC Symbol;Acc:HGNC:4446]",{"v":0.041128,"d":"0.04"},{"v":0.188915,"d":"0.19"},{"v":0.217706375883334,"d":"0.22"},{"v":-2.19954443508485,"d":"-2.20"},1,1,"down","no"]
[194982,0,"chr9","+",136993381,136993977,"ENST00000463765",2,496,"MSTRG.15113","PAXX","GO:0005634(nucleus);GO:0042803(protein homodimerization activity);GO:0006303(double-strand break repair via nonhomologous end joining);GO:0006281(DNA repair);GO:0006974(cellular response to DNA damage stimulus);GO:0005515(protein binding);GO:0070062(extracellular exosome);GO:0035861(site of double-strand break);GO:0032947(protein complex scaffold);GO:0051103(DNA ligation involved in DNA repair);GO:0043564(Ku70:Ku80 complex);GO:0070419(nonhomologous end joining complex)","NA","NA","NA","PAXX, non-homologous end joining factor [Source:HGNC Symbol;Acc:HGNC:27849]",{"v":0.429223,"d":"0.43"},0,"inf","inf",1,1,"up","no"]
[106383,0,"chr19","-",57803841,57813404,"ENST00000594473",2,335,"MSTRG.8462","ZNF552","GO:0003676(nucleic acid binding);GO:0006355(regulation of transcription, DNA-templated);GO:0005622(intracellular);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0045892(negative regulation of transcription, DNA-templated)","NA","NA","NA","zinc finger protein 552 [Source:HGNC Symbol;Acc:HGNC:26135]",{"v":0.102293,"d":"0.10"},{"v":0.793784,"d":"0.79"},{"v":0.128867550870262,"d":"0.13"},{"v":-2.95603905920966,"d":"-2.96"},1,1,"down","no"]
[74326,0,"chr16","+",67171634,67173003,"ENST00000568199",2,613,"MSTRG.6012","NOL3","GO:0042981(regulation of apoptotic process);GO:0006397(mRNA processing);GO:0008380(RNA splicing);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0046872(metal ion binding);GO:0005739(mitochondrion);GO:0005515(protein binding);GO:0006915(apoptotic process);GO:0005730(nucleolus);GO:0005509(calcium ion binding);GO:0042802(identical protein binding);GO:0016529(sarcoplasmic reticulum);GO:0043066(negative regulation of apoptotic process);GO:0051259(protein oligomerization);GO:0003723(RNA binding);GO:0005829(cytosol);GO:0089720(caspase binding);GO:2001237(negative regulation of extrinsic apoptotic signaling pathway);GO:0043027(cysteine-type endopeptidase inhibitor activity involved in apoptotic process);GO:0090201(negative regulation of release of cytochrome c from mitochondria);GO:0005102(receptor binding);GO:0005123(death receptor binding);GO:0035877(death effector domain binding);GO:0001666(response to hypoxia);GO:0001974(blood vessel remodeling);GO:0002931(response to ischemia);GO:0006376(mRNA splice site selection);GO:0010468(regulation of gene expression);GO:0010659(cardiac muscle cell apoptotic process);GO:0010664(negative regulation of striated muscle cell apoptotic process);GO:0010667(negative regulation of cardiac muscle cell apoptotic process);GO:0010804(negative regulation of tumor necrosis factor-mediated signaling pathway);GO:0014736(negative regulation of muscle atrophy);GO:0014808(release of sequestered calcium ion into cytosol by sarcoplasmic reticulum);GO:0014876(response to injury involved in regulation of muscle adaptation);GO:0042345(regulation of NF-kappaB import into nucleus);GO:0060547(negative regulation of necrotic cell death);GO:0097193(intrinsic apoptotic signaling pathway);GO:1902109(negative regulation of mitochondrial membrane permeability involved in apoptotic process);GO:1902176(negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway);GO:1990001(inhibition of cysteine-type endopeptidase activity involved in apoptotic process);GO:0016528(sarcoplasm)","NA","NA","NA","nucleolar protein 3 [Source:HGNC Symbol;Acc:HGNC:7869]",{"v":0.67977,"d":"0.68"},{"v":0.090488,"d":"0.09"},{"v":7.51226681990982,"d":"7.51"},{"v":2.90924830539378,"d":"2.91"},1,1,"up","no"]
[164009,0,"chr6","-",30291006,30326376,"ENST00000454129",3,4433,"MSTRG.12766","HCG18","NA","NA","NA","NA","HLA complex group 18 (non-protein coding) [Source:HGNC Symbol;Acc:HGNC:31337]",{"v":0.083513,"d":"0.08"},0,"inf","inf",1,1,"up","no"]
[50663,0,"chr13","-",52844459,52845693,"ENST00000613548",2,744,"ENSG00000136099","PCDH8","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005509(calcium ion binding);GO:0007155(cell adhesion);GO:0007156(homophilic cell adhesion via plasma membrane adhesion molecules);GO:0005886(plasma membrane);GO:0042995(cell projection);GO:0030054(cell junction);GO:0045202(synapse);GO:0045211(postsynaptic membrane);GO:0030425(dendrite);GO:0007399(nervous system development);GO:0005887(integral component of plasma membrane);GO:0007267(cell-cell signaling);GO:0042734(presynaptic membrane);GO:0001756(somitogenesis);GO:0007268(chemical synaptic transmission);GO:0016331(morphogenesis of embryonic epithelium)","NA","NA","NA","protocadherin 8 [Source:HGNC Symbol;Acc:HGNC:8660]",0,0,1,0,1,1,"no","no"]
[73612,0,"chr16","+",57628624,57651367,"ENST00000563374",4,568,"MSTRG.5971","ADGRG1","GO:0005622(intracellular);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0004930(G-protein coupled receptor activity);GO:0007186(G-protein coupled receptor signaling pathway);GO:0007155(cell adhesion);GO:0005886(plasma membrane);GO:0004871(signal transducer activity);GO:0007165(signal transduction);GO:0005576(extracellular region);GO:0004888(transmembrane signaling receptor activity);GO:0007166(cell surface receptor signaling pathway);GO:0007275(multicellular organism development);GO:0007399(nervous system development);GO:0030154(cell differentiation);GO:0045121(membrane raft);GO:0008201(heparin binding);GO:0070062(extracellular exosome);GO:0050840(extracellular matrix binding);GO:0008285(negative regulation of cell proliferation);GO:0005887(integral component of plasma membrane);GO:0007267(cell-cell signaling);GO:0045785(positive regulation of cell adhesion);GO:0016477(cell migration);GO:0001525(angiogenesis);GO:0007266(Rho protein signal transduction);GO:0005518(collagen binding);GO:0070528(protein kinase C signaling);GO:0035025(positive regulation of Rho protein signal transduction);GO:2001223(negative regulation of neuron migration);GO:0021819(layer formation in cerebral cortex);GO:0021801(cerebral cortex radial glia guided migration);GO:0007420(brain development);GO:0010573(vascular endothelial growth factor production);GO:0097451(glial limiting end-foot);GO:0021796(cerebral cortex regionalization);GO:0072520(seminiferous tubule development);GO:2000179(positive regulation of neural precursor cell proliferation)","NA","NA","NA","adhesion G protein-coupled receptor G1 [Source:HGNC Symbol;Acc:HGNC:4512]",{"v":0.029593,"d":"0.03"},0,"inf","inf",1,1,"up","no"]
[162577,0,"chr6","+",4776442,4954510,"ENST00000472453",6,1764,"MSTRG.12642","CDYL","GO:0005634(nucleus);GO:0016607(nuclear speck);GO:0005654(nucleoplasm);GO:0016740(transferase activity);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003824(catalytic activity);GO:0016746(transferase activity, transferring acyl groups);GO:0008152(metabolic process);GO:0005515(protein binding);GO:0016604(nuclear body);GO:0004402(histone acetyltransferase activity);GO:0016573(histone acetylation);GO:1903507(negative regulation of nucleic acid-templated transcription);GO:0003714(transcription corepressor activity);GO:0030674(protein binding, bridging);GO:0007283(spermatogenesis);GO:0035064(methylated histone binding);GO:0016020(membrane);GO:0016021(integral component of membrane)","NA","NA","NA","chromodomain Y like [Source:HGNC Symbol;Acc:HGNC:1811]",{"v":0.031182,"d":"0.03"},0,"inf","inf",1,1,"up","no"]
[47005,0,"chr12","-",113298781,113308843,"ENST00000550047",4,2493,"MSTRG.3761","SLC8B1","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0055085(transmembrane transport);GO:0005743(mitochondrial inner membrane);GO:0005739(mitochondrion);GO:0006811(ion transport);GO:0015297(antiporter activity);GO:0006814(sodium ion transport);GO:0006816(calcium ion transport);GO:0050896(response to stimulus);GO:0005886(plasma membrane);GO:0042803(protein homodimerization activity);GO:0086036(regulation of cardiac muscle cell membrane potential);GO:0050796(regulation of insulin secretion);GO:0042593(glucose homeostasis);GO:0006851(mitochondrial calcium ion transmembrane transport);GO:0051560(mitochondrial calcium ion homeostasis);GO:0099093(mitochondrial calcium release);GO:0051480(regulation of cytosolic calcium ion concentration);GO:0005432(calcium:sodium antiporter activity);GO:2001256(regulation of store-operated calcium entry);GO:0032592(integral component of mitochondrial membrane);GO:0015368(calcium:cation antiporter activity);GO:0042802(identical protein binding);GO:0086038(calcium:sodium antiporter activity involved in regulation of cardiac muscle cell membrane potential);GO:0035725(sodium ion transmembrane transport);GO:0070588(calcium ion transmembrane transport);GO:1901623(regulation of lymphocyte chemotaxis);GO:0030061(mitochondrial crista);GO:0042383(sarcolemma)","NA","NA","NA","solute carrier family 8 member B1 [Source:HGNC Symbol;Acc:HGNC:26175]",{"v":1.636953,"d":"1.64"},{"v":0.063537,"d":"0.06"},{"v":25.7637754379338,"d":"25.76"},{"v":4.68727211716271,"d":"4.69"},1,1,"up","no"]
[43802,0,"chr12","+",62466848,62592865,"ENST00000393629",34,5612,"ENSG00000061987","MON2","GO:0006810(transport);GO:0015031(protein transport);GO:0005829(cytosol);GO:0005515(protein binding);GO:0070062(extracellular exosome);GO:0006895(Golgi to endosome transport)","NA","NA","NA","MON2 homolog, regulator of endosome-to-Golgi trafficking [Source:HGNC Symbol;Acc:HGNC:29177]",0,0,1,0,1,1,"no","no"]
[128840,0,"chr22","+",20703716,20704558,"ENST00000428752",3,614,"ENSG00000226287","TMEM191A","NA","NA","NA","NA","transmembrane protein 191A (pseudogene) [Source:HGNC Symbol;Acc:HGNC:25317]",0,{"v":0.026266,"d":"0.03"},"-inf","-inf",1,1,"down","no"]
[134847,0,"chr3","+",38496272,38525951,"ENST00000287675",6,2792,"ENSG00000157036","EXOG","GO:0003676(nucleic acid binding);GO:0016020(membrane);GO:0046872(metal ion binding);GO:0016787(hydrolase activity);GO:0005743(mitochondrial inner membrane);GO:0005739(mitochondrion);GO:0090305(nucleic acid phosphodiester bond hydrolysis);GO:0004519(endonuclease activity);GO:0004518(nuclease activity);GO:0008150(biological_process);GO:0005575(cellular_component);GO:0043234(protein complex);GO:0008409(5'-3' exonuclease activity);GO:0016021(integral component of membrane)","NA","NA","NA","exo/endonuclease G [Source:HGNC Symbol;Acc:HGNC:3347]",{"v":0.563441,"d":"0.56"},{"v":0.055995,"d":"0.06"},{"v":10.0623448522189,"d":"10.06"},{"v":3.33089463387512,"d":"3.33"},1,1,"up","no"]
[127379,0,"chr21","+",41450928,41452820,"ENST00000491110",2,516,"MSTRG.10064","MX1","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005525(GTP binding);GO:0000166(nucleotide binding);GO:0005829(cytosol);GO:0031965(nuclear membrane);GO:0003924(GTPase activity);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005515(protein binding);GO:0048471(perinuclear region of cytoplasm);GO:0002376(immune system process);GO:0045087(innate immune response);GO:0042802(identical protein binding);GO:0051607(defense response to virus);GO:0008017(microtubule binding);GO:0009615(response to virus);GO:0045071(negative regulation of viral genome replication);GO:0007165(signal transduction);GO:0006915(apoptotic process);GO:0006952(defense response);GO:0060337(type I interferon signaling pathway);GO:0003374(dynamin family protein polymerization involved in mitochondrial fission);GO:0061025(membrane fusion);GO:0031966(mitochondrial membrane);GO:0034340(response to type I interferon);GO:0000266(mitochondrial fission)","05162(Measles);05164(Influenza A);05165(Human papillomavirus infection)","NA","NA","MX dynamin like GTPase 1 [Source:HGNC Symbol;Acc:HGNC:7532]",0,{"v":0.025785,"d":"0.03"},"-inf","-inf",1,1,"down","no"]
[156478,0,"chr5","-",87404842,87412889,"ENST00000513499",5,606,"ENSG00000134480","CCNH","GO:0006351(transcription, DNA-templated);GO:0045859(regulation of protein kinase activity);GO:0016538(cyclin-dependent protein serine/threonine kinase regulator activity);GO:0070985(TFIIK complex);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0006355(regulation of transcription, DNA-templated);GO:0006468(protein phosphorylation);GO:0005515(protein binding);GO:0007049(cell cycle);GO:0016310(phosphorylation);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0006366(transcription from RNA polymerase II promoter);GO:0000086(G2/M transition of mitotic cell cycle);GO:0006368(transcription elongation from RNA polymerase II promoter);GO:0006370(7-methylguanosine mRNA capping);GO:0006367(transcription initiation from RNA polymerase II promoter);GO:0000082(G1/S transition of mitotic cell cycle);GO:0006361(transcription initiation from RNA polymerase I promoter);GO:0006362(transcription elongation from RNA polymerase I promoter);GO:0006363(termination of RNA polymerase I transcription);GO:0008094(DNA-dependent ATPase activity);GO:0006283(transcription-coupled nucleotide-excision repair);GO:0045737(positive regulation of cyclin-dependent protein serine/threonine kinase activity);GO:1901409(positive regulation of phosphorylation of RNA polymerase II C-terminal domain);GO:0050821(protein stabilization);GO:0008353(RNA polymerase II carboxy-terminal domain kinase activity);GO:0006294(nucleotide-excision repair, preincision complex assembly);GO:0019907(cyclin-dependent protein kinase activating kinase holoenzyme complex);GO:0005675(holo TFIIH complex);GO:0016301(kinase activity)","03022(Basal transcription factors);03420(Nucleotide excision repair);04110(Cell cycle)","NA","NA","cyclin H [Source:HGNC Symbol;Acc:HGNC:1594]",0,0,1,0,1,1,"no","no"]
[119613,0,"chr2","-",221420445,221425540,"ENST00000472696",3,531,"ENSG00000116106","EPHA4","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0004713(protein tyrosine kinase activity);GO:0005003(ephrin receptor activity);GO:0007169(transmembrane receptor protein tyrosine kinase signaling pathway);GO:0018108(peptidyl-tyrosine phosphorylation);GO:0005887(integral component of plasma membrane);GO:0048013(ephrin receptor signaling pathway);GO:0005737(cytoplasm);GO:0007155(cell adhesion);GO:0005886(plasma membrane);GO:0042995(cell projection);GO:0004714(transmembrane receptor protein tyrosine kinase activity);GO:0007275(multicellular organism development);GO:0030054(cell junction);GO:0045202(synapse);GO:0045211(postsynaptic membrane);GO:0007399(nervous system development);GO:0030425(dendrite);GO:0005515(protein binding);GO:0005768(endosome);GO:0030424(axon);GO:0005769(early endosome);GO:0014069(postsynaptic density);GO:0031901(early endosome membrane);GO:1904646(cellular response to amyloid-beta);GO:0046777(protein autophosphorylation);GO:0043087(regulation of GTPase activity);GO:0050770(regulation of axonogenesis);GO:0061001(regulation of dendritic spine morphogenesis);GO:0048681(negative regulation of axon regeneration);GO:0008045(motor neuron axon guidance);GO:1900272(negative regulation of long-term synaptic potentiation);GO:1905244(regulation of modification of synaptic structure);GO:0010977(negative regulation of neuron projection development);GO:0061098(positive regulation of protein tyrosine kinase activity);GO:1902961(positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process);GO:0050821(protein stabilization);GO:1902004(positive regulation of amyloid-beta formation);GO:1903051(negative regulation of proteolysis involved in cellular protein catabolic process);GO:0005005(transmembrane-ephrin receptor activity);GO:0005004(GPI-linked ephrin receptor activity);GO:0097155(fasciculation of sensory neuron axon);GO:0097156(fasciculation of motor neuron axon);GO:1990782(protein tyrosine kinase binding);GO:0043197(dendritic spine);GO:0042731(PH domain binding);GO:0097161(DH domain binding);GO:0021957(corticospinal tract morphogenesis);GO:0048710(regulation of astrocyte differentiation);GO:0097485(neuron projection guidance);GO:2001108(positive regulation of Rho guanyl-nucleotide exchange factor activity);GO:0043198(dendritic shaft);GO:0042802(identical protein binding);GO:0046875(ephrin receptor binding);GO:0007411(axon guidance);GO:0007628(adult walking behavior);GO:0008347(glial cell migration);GO:0043507(positive regulation of JUN kinase activity);GO:0050775(positive regulation of dendrite morphogenesis);GO:0072178(nephric duct morphogenesis);GO:0106030(-);GO:0005741(mitochondrial outer membrane);GO:0005783(endoplasmic reticulum);GO:0005794(Golgi apparatus);GO:0009986(cell surface);GO:0030175(filopodium);GO:0031594(neuromuscular junction);GO:0043204(perikaryon);GO:0043679(axon terminus);GO:0044295(axonal growth cone);GO:0044297(cell body)","04360(Axon guidance)","NA","NA","EPH receptor A4 [Source:HGNC Symbol;Acc:HGNC:3388]",0,0,1,0,1,1,"no","no"]
[32350,0,"chr11","+",69371463,69372512,"ENST00000561588",2,372,"ENSG00000260877","AP005233.2","NA","NA","NA","NA","NA",0,0,1,0,1,1,"no","no"]
[174812,0,"chr7","-",73048481,73057911,"ENST00000340073",8,2281,"MSTRG.13692","SPDYE11","NA","NA","NA","NA","speedy/RINGO cell cycle regulator family member E11 [Source:HGNC Symbol;Acc:HGNC:51507]",{"v":0.068365,"d":"0.07"},{"v":0.087545,"d":"0.09"},{"v":0.780912673482209,"d":"0.78"},{"v":-0.356766868643201,"d":"-0.36"},1,1,"down","no"]
[39600,0,"chr12","-",22470836,22472445,"ENST00000540245",4,425,"MSTRG.3254","C2CD5","GO:0006810(transport);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0015031(protein transport);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0042995(cell projection);GO:0005815(microtubule organizing center);GO:0030659(cytoplasmic vesicle membrane);GO:0031410(cytoplasmic vesicle);GO:0005544(calcium-dependent phospholipid binding);GO:0005509(calcium ion binding);GO:0008289(lipid binding);GO:0005938(cell cortex);GO:0032587(ruffle membrane);GO:0090314(positive regulation of protein targeting to membrane);GO:0001726(ruffle);GO:0032869(cellular response to insulin stimulus);GO:0010828(positive regulation of glucose transport);GO:0031340(positive regulation of vesicle fusion);GO:0038028(insulin receptor signaling pathway via phosphatidylinositol 3-kinase);GO:0065002(intracellular protein transmembrane transport);GO:0006906(vesicle fusion);GO:0072659(protein localization to plasma membrane);GO:2001275(positive regulation of glucose import in response to insulin stimulus)","NA","NA","NA","C2 calcium dependent domain containing 5 [Source:HGNC Symbol;Acc:HGNC:29062]",{"v":0.011374,"d":"0.01"},{"v":0.046075,"d":"0.05"},{"v":0.24685838307108,"d":"0.25"},{"v":-2.01824445645321,"d":"-2.02"},1,1,"down","no"]
[77462,0,"chr17","-",1480527,1491669,"ENST00000570984",7,901,"ENSG00000197879","MYO1C","GO:0006810(transport);GO:0051028(mRNA transport);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0015031(protein transport);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0003774(motor activity);GO:0016459(myosin complex);GO:0003779(actin binding);GO:0005886(plasma membrane);GO:0042995(cell projection);GO:0016604(nuclear body);GO:0031410(cytoplasmic vesicle);GO:0045121(membrane raft);GO:0005643(nuclear pore);GO:0005654(nucleoplasm);GO:0005730(nucleolus);GO:0038096(Fc-gamma receptor signaling pathway involved in phagocytosis);GO:0005516(calmodulin binding);GO:0005515(protein binding);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0031941(filamentous actin);GO:0030335(positive regulation of cell migration);GO:0090314(positive regulation of protein targeting to membrane);GO:0005902(microvillus);GO:0005102(receptor binding);GO:0016461(unconventional myosin complex);GO:0000146(microfilament motor activity);GO:0008022(protein C-terminus binding);GO:0017160(Ral GTPase binding);GO:0030898(actin-dependent ATPase activity);GO:0051015(actin filament binding);GO:0006605(protein targeting);GO:0006612(protein targeting to membrane);GO:0030838(positive regulation of actin filament polymerization);GO:0038089(positive regulation of cell migration by vascular endothelial growth factor signaling pathway);GO:0045815(positive regulation of gene expression, epigenetic);GO:1900078(positive regulation of cellular response to insulin stimulus);GO:1900748(positive regulation of vascular endothelial growth factor signaling pathway);GO:2000810(regulation of bicellular tight junction assembly);GO:0001726(ruffle);GO:0005903(brush border);GO:0009925(basal plasma membrane);GO:0016328(lateral plasma membrane);GO:0032420(stereocilium);GO:0032421(stereocilium bundle);GO:0032587(ruffle membrane);GO:0045160(myosin I complex);GO:0060171(stereocilium membrane)","NA","NA","NA","myosin IC [Source:HGNC Symbol;Acc:HGNC:7597]",{"v":0.148047,"d":"0.15"},0,"inf","inf",1,1,"up","no"]
[131229,0,"chr22","+",38200767,38204050,"ENST00000624676",1,3284,"MSTRG.10449","MAFF","GO:0005634(nucleus);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0005739(mitochondrion);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0005654(nucleoplasm);GO:0001228(transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding);GO:0043565(sequence-specific DNA binding);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0006366(transcription from RNA polymerase II promoter);GO:0007596(blood coagulation);GO:0007567(parturition);GO:0001701(in utero embryonic development);GO:0035914(skeletal muscle cell differentiation);GO:0045604(regulation of epidermal cell differentiation)","NA","NA","NA","MAF bZIP transcription factor F [Source:HGNC Symbol;Acc:HGNC:6780]",{"v":0.015652,"d":"0.02"},{"v":0.034246,"d":"0.03"},{"v":0.457046078374117,"d":"0.46"},{"v":-1.12958847295044,"d":"-1.13"},1,1,"down","no"]
[110154,0,"chr2","+",62705652,62864904,"ENST00000405482",9,1311,"ENSG00000115504","EHBP1","GO:0006810(transport);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0015031(protein transport);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0005768(endosome);GO:0006897(endocytosis)","NA","NA","NA","EH domain binding protein 1 [Source:HGNC Symbol;Acc:HGNC:29144]",{"v":0.323712,"d":"0.32"},0,"inf","inf",1,1,"up","no"]
[74734,0,"chr16","-",67992557,67994328,"ENST00000574865",3,559,"MSTRG.6048","DPEP2","GO:0016020(membrane);GO:0046872(metal ion binding);GO:0016787(hydrolase activity);GO:0008233(peptidase activity);GO:0006508(proteolysis);GO:0008237(metallopeptidase activity);GO:0008235(metalloexopeptidase activity);GO:0008239(dipeptidyl-peptidase activity);GO:0016805(dipeptidase activity);GO:0031225(anchored component of membrane);GO:0008238(exopeptidase activity)","NA","NA","NA","dipeptidase 2 [Source:HGNC Symbol;Acc:HGNC:23028]",{"v":0.708244,"d":"0.71"},{"v":1.095679,"d":"1.10"},{"v":0.646397348128421,"d":"0.65"},{"v":-0.629506815500972,"d":"-0.63"},1,1,"down","no"]
[96604,0,"chr19","-",10927598,10928547,"ENST00000592505",2,530,"MSTRG.7815","YIPF2","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005515(protein binding);GO:0017137(Rab GTPase binding);GO:0005794(Golgi apparatus);GO:0030133(transport vesicle)","NA","NA","NA","Yip1 domain family member 2 [Source:HGNC Symbol;Acc:HGNC:28476]",{"v":0.343751,"d":"0.34"},{"v":0.086997,"d":"0.09"},{"v":3.95129717116682,"d":"3.95"},{"v":1.98232635333818,"d":"1.98"},1,1,"up","no"]
[165283,0,"chr6","-",33416542,33418288,"ENST00000611509",5,1199,"MSTRG.12953","CUTA","GO:0016020(membrane);GO:0005515(protein binding);GO:0005507(copper ion binding);GO:0070062(extracellular exosome);GO:0010038(response to metal ion);GO:0019899(enzyme binding);GO:0008104(protein localization);GO:0016021(integral component of membrane)","NA","NA","NA","cutA divalent cation tolerance homolog [Source:HGNC Symbol;Acc:HGNC:21101]",{"v":0.925163,"d":"0.93"},{"v":0.458031,"d":"0.46"},{"v":2.01986983413786,"d":"2.02"},{"v":1.01426232481147,"d":"1.01"},1,1,"up","no"]
[99832,0,"chr19","-",34593329,34632976,"ENST00000595326",4,643,"ENSG00000205209","SCGB2B2","GO:0005576(extracellular region)","NA","NA","NA","secretoglobin family 2B member 2 [Source:HGNC Symbol;Acc:HGNC:27616]",0,0,1,0,1,1,"no","no"]
[180515,0,"chr7","+",155746586,155781485,"ENST00000341148",5,7058,"MSTRG.14155","RBM33","GO:0003676(nucleic acid binding);GO:0003723(RNA binding)","NA","NA","NA","RNA binding motif protein 33 [Source:HGNC Symbol;Acc:HGNC:27223]",0,0,1,0,1,1,"no","no"]
[95647,0,"chr19","+",7069705,7087968,"ENST00000414706",8,5736,"ENSG00000130544","ZNF557","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0005622(intracellular)","NA","NA","NA","zinc finger protein 557 [Source:HGNC Symbol;Acc:HGNC:28632]",{"v":0.246548,"d":"0.25"},0,"inf","inf",1,1,"up","no"]
[57646,0,"chr14","+",90396502,90404496,"ENST00000557020",5,557,"MSTRG.4607","CALM1","GO:0005509(calcium ion binding);GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0000922(spindle pole);GO:0005819(spindle);GO:0044325(ion channel binding);GO:0090150(establishment of protein localization to membrane);GO:0090151(establishment of protein localization to mitochondrial membrane);GO:1900242(regulation of synaptic vesicle endocytosis);GO:2000300(regulation of synaptic vesicle exocytosis);GO:0014069(postsynaptic density);GO:0030672(synaptic vesicle membrane);GO:0031966(mitochondrial membrane);GO:0043209(myelin sheath);GO:0019855(calcium channel inhibitor activity);GO:0060315(negative regulation of ryanodine-sensitive calcium-release channel activity)","04014(Ras signaling pathway);04015(Rap1 signaling pathway);04371(Apelin signaling pathway);04020(Calcium signaling pathway);04070(Phosphatidylinositol signaling system);04024(cAMP signaling pathway);04022(cGMP - PKG signaling pathway);04114(Oocyte meiosis);04218(Cellular senescence);04910(Insulin signaling pathway);04922(Glucagon signaling pathway);04912(GnRH signaling pathway);04915(Estrogen signaling pathway);04921(Oxytocin signaling pathway);04916(Melanogenesis);04924(Renin secretion);04925(Aldosterone synthesis and secretion);04261(Adrenergic signaling in cardiomyocytes);04270(Vascular smooth muscle contraction);04970(Salivary secretion);04971(Gastric acid secretion);04728(Dopaminergic synapse);04720(Long-term potentiation);04722(Neurotrophin signaling pathway);04744(Phototransduction);04740(Olfactory transduction);04750(Inflammatory mediator regulation of TRP channels);04713(Circadian entrainment);05200(Pathways in cancer);05214(Glioma);05010(Alzheimer's disease);05031(Amphetamine addiction);05034(Alcoholism);05418(Fluid shear stress and atherosclerosis);05133(Pertussis);05152(Tuberculosis);05167(Kaposi's sarcoma-associated herpesvirus infection)","NA","NA","calmodulin 1 [Source:HGNC Symbol;Acc:HGNC:1442]",{"v":0.32184,"d":"0.32"},{"v":1.139242,"d":"1.14"},{"v":0.282503629606352,"d":"0.28"},{"v":-1.82365869149601,"d":"-1.82"},1,1,"down","no"]
[51962,0,"chr13","-",113177613,113178478,"ENST00000462653",2,669,"MSTRG.4113","PCID2","GO:0005515(protein binding);GO:0045893(positive regulation of transcription, DNA-templated);GO:0003690(double-stranded DNA binding);GO:0003723(RNA binding);GO:0005575(cellular_component);GO:0006368(transcription elongation from RNA polymerase II promoter);GO:0005643(nuclear pore);GO:0043066(negative regulation of apoptotic process);GO:0090267(positive regulation of mitotic cell cycle spindle assembly checkpoint);GO:0048536(spleen development);GO:2000117(negative regulation of cysteine-type endopeptidase activity);GO:0043488(regulation of mRNA stability);GO:0000973(posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery);GO:0035327(transcriptionally active chromatin);GO:0016973(poly(A)+ mRNA export from nucleus);GO:0071033(nuclear retention of pre-mRNA at the site of transcription);GO:0070390(transcription export complex 2);GO:0045579(positive regulation of B cell differentiation)","NA","NA","NA","PCI domain containing 2 [Source:HGNC Symbol;Acc:HGNC:25653]",0,0,1,0,1,1,"no","no"]
[184070,0,"chr8","+",58411359,58434941,"ENST00000522978",7,717,"MSTRG.14367","UBXN2B","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005794(Golgi apparatus);GO:0005829(cytosol);GO:0005783(endoplasmic reticulum);GO:0050790(regulation of catalytic activity);GO:0005515(protein binding);GO:0043161(proteasome-mediated ubiquitin-dependent protein catabolic process);GO:0000045(autophagosome assembly);GO:0007030(Golgi organization);GO:0043130(ubiquitin binding);GO:0061025(membrane fusion);GO:0019888(protein phosphatase regulator activity);GO:0031468(nuclear envelope reassembly)","NA","NA","NA","UBX domain protein 2B [Source:HGNC Symbol;Acc:HGNC:27035]",0,{"v":0.163362,"d":"0.16"},"-inf","-inf",1,1,"down","no"]
[130150,0,"chr22","-",30262829,30266840,"ENST00000215781",3,1854,"ENSG00000099985","OSM","GO:0008284(positive regulation of cell proliferation);GO:0005622(intracellular);GO:0002675(positive regulation of acute inflammatory response);GO:0005576(extracellular region);GO:0006955(immune response);GO:0005125(cytokine activity);GO:0005615(extracellular space);GO:0040008(regulation of growth);GO:0050731(positive regulation of peptidyl-tyrosine phosphorylation);GO:0007275(multicellular organism development);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0008283(cell proliferation);GO:0008285(negative regulation of cell proliferation);GO:0051781(positive regulation of cell division);GO:0008083(growth factor activity);GO:0033138(positive regulation of peptidyl-serine phosphorylation);GO:0043410(positive regulation of MAPK cascade);GO:0005147(oncostatin-M receptor binding);GO:0007260(tyrosine phosphorylation of STAT protein);GO:0007422(peripheral nervous system development);GO:0009408(response to heat);GO:0038165(oncostatin-M-mediated signaling pathway);GO:0042531(positive regulation of tyrosine phosphorylation of STAT protein);GO:0045835(negative regulation of meiotic nuclear division);GO:0046888(negative regulation of hormone secretion);GO:0048266(behavioral response to pain);GO:2001235(positive regulation of apoptotic signaling pathway)","04630(Jak-STAT signaling pathway);04151(PI3K-Akt signaling pathway);04060(Cytokine-cytokine receptor interaction)","K05418","NA","oncostatin M [Source:HGNC Symbol;Acc:HGNC:8506]",{"v":0.8104,"d":"0.81"},{"v":0.153515,"d":"0.15"},{"v":5.27896296778816,"d":"5.28"},{"v":2.40025454546,"d":"2.40"},1,1,"up","no"]
[102646,0,"chr19","+",44955558,44974490,"ENST00000585961",4,572,"MSTRG.8218","CLPTM1","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005515(protein binding);GO:0007275(multicellular organism development);GO:0030154(cell differentiation);GO:0005887(integral component of plasma membrane);GO:0009897(external side of plasma membrane);GO:0033081(regulation of T cell differentiation in thymus)","NA","NA","NA","CLPTM1, transmembrane protein [Source:HGNC Symbol;Acc:HGNC:2087]",{"v":0.051099,"d":"0.05"},{"v":5.4e-05,"d":"0.00"},{"v":946.277777777778,"d":"946.28"},{"v":9.88611993549296,"d":"9.89"},1,1,"up","no"]
[161561,0,"chr5","-",177402163,177403750,"ENST00000504406",3,943,"MSTRG.12576","F12","GO:0005615(extracellular space);GO:0016787(hydrolase activity);GO:0005509(calcium ion binding);GO:0005576(extracellular region);GO:0005515(protein binding);GO:0008233(peptidase activity);GO:0006508(proteolysis);GO:0004252(serine-type endopeptidase activity);GO:0008236(serine-type peptidase activity);GO:0005886(plasma membrane);GO:0070062(extracellular exosome);GO:0045087(innate immune response);GO:0007596(blood coagulation);GO:0007599(hemostasis);GO:0016485(protein processing);GO:0007597(blood coagulation, intrinsic pathway);GO:0030194(positive regulation of blood coagulation);GO:0042730(fibrinolysis);GO:0051919(positive regulation of fibrinolysis);GO:0051787(misfolded protein binding);GO:0002353(plasma kallikrein-kinin cascade);GO:0002542(Factor XII activation);GO:0010756(positive regulation of plasminogen activation);GO:0016540(protein autoprocessing);GO:0030193(regulation of blood coagulation);GO:0031638(zymogen activation);GO:0051788(response to misfolded protein)","04610(Complement and coagulation cascades)","NA","NA","coagulation factor XII [Source:HGNC Symbol;Acc:HGNC:3530]",0,0,1,0,1,1,"no","no"]
[154240,0,"chr5","+",36667717,36669958,"ENST00000624112",1,2242,"ENSG00000279400","AC008957.3","NA","NA","NA","NA","NA",0,0,1,0,1,1,"no","no"]
[86041,0,"chr17","-",58205740,58219605,"ENST00000537529",18,2083,"ENSG00000011143","MKS1","GO:0005737(cytoplasm);GO:0005856(cytoskeleton);GO:0042995(cell projection);GO:0005813(centrosome);GO:0005815(microtubule organizing center);GO:0005515(protein binding);GO:0060271(cilium assembly);GO:0005929(cilium);GO:0005829(cytosol);GO:0030030(cell projection organization);GO:0036064(ciliary basal body);GO:0097711(ciliary basal body docking);GO:0036038(MKS complex);GO:0001843(neural tube closure);GO:0007368(determination of left/right symmetry);GO:0008589(regulation of smoothened signaling pathway);GO:0010669(epithelial structure maintenance);GO:0042733(embryonic digit morphogenesis);GO:0044458(motile cilium assembly);GO:0048706(embryonic skeletal system development);GO:0048754(branching morphogenesis of an epithelial tube);GO:0060122(inner ear receptor stereocilium organization);GO:0060322(head development);GO:0060828(regulation of canonical Wnt signaling pathway);GO:0061009(common bile duct development);GO:1901620(regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning);GO:1905515(non-motile cilium assembly);GO:1990403(embryonic brain development);GO:2000095(regulation of Wnt signaling pathway, planar cell polarity pathway);GO:0005814(centriole);GO:0016020(membrane);GO:0035869(ciliary transition zone)","NA","NA","NA","Meckel syndrome, type 1 [Source:HGNC Symbol;Acc:HGNC:7121]",{"v":0.019128,"d":"0.02"},{"v":0.010902,"d":"0.01"},{"v":1.75454045129334,"d":"1.75"},{"v":0.811093209756356,"d":"0.81"},1,1,"up","no"]
[119782,0,"chr2","+",227164565,227314792,"ENST00000396578",52,8097,"MSTRG.9462","COL4A3","GO:0043231(intracellular membrane-bounded organelle);GO:0005783(endoplasmic reticulum);GO:0007155(cell adhesion);GO:0010951(negative regulation of endopeptidase activity);GO:0005576(extracellular region);GO:0005581(collagen trimer);GO:0005578(proteinaceous extracellular matrix);GO:0005201(extracellular matrix structural constituent);GO:0005604(basement membrane);GO:0005515(protein binding);GO:0008283(cell proliferation);GO:0030574(collagen catabolic process);GO:0005178(integrin binding);GO:0005788(endoplasmic reticulum lumen);GO:0030198(extracellular matrix organization);GO:0005198(structural molecule activity);GO:0016525(negative regulation of angiogenesis);GO:0008285(negative regulation of cell proliferation);GO:0006919(activation of cysteine-type endopeptidase activity involved in apoptotic process);GO:0007605(sensory perception of sound);GO:0032836(glomerular basement membrane development);GO:0008015(blood circulation);GO:0007166(cell surface receptor signaling pathway);GO:0008191(metalloendopeptidase inhibitor activity);GO:0005587(collagen type IV trimer);GO:0038063(collagen-activated tyrosine kinase receptor signaling pathway);GO:0072577(endothelial cell apoptotic process)","04151(PI3K-Akt signaling pathway);04512(ECM-receptor interaction);04510(Focal adhesion);04926(Relaxin signaling pathway);04974(Protein digestion and absorption);05200(Pathways in cancer);05222(Small cell lung cancer);04933(AGE-RAGE signaling pathway in diabetic complications);05165(Human papillomavirus infection);05146(Amoebiasis)","K06237","NA","collagen type IV alpha 3 chain [Source:HGNC Symbol;Acc:HGNC:2204]",{"v":0.184885,"d":"0.18"},{"v":0.053092,"d":"0.05"},{"v":3.48235139003993,"d":"3.48"},{"v":1.80006178687474,"d":"1.80"},1,1,"up","no"]
[69853,0,"chr16","-",14608107,14610699,"ENST00000563155",3,335,"MSTRG.5680","PARN","GO:0005634(nucleus);GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0016787(hydrolase activity);GO:0005515(protein binding);GO:0004527(exonuclease activity);GO:0004518(nuclease activity);GO:0005730(nucleolus);GO:0005829(cytosol);GO:0019901(protein kinase binding);GO:0043488(regulation of mRNA stability);GO:0004535(poly(A)-specific ribonuclease activity);GO:0000289(nuclear-transcribed mRNA poly(A) tail shortening);GO:0006402(mRNA catabolic process);GO:0032212(positive regulation of telomere maintenance via telomerase);GO:0051973(positive regulation of telomerase activity);GO:0070034(telomerase RNA binding);GO:0000184(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay);GO:0007292(female gamete generation);GO:0090669(telomerase RNA stabilization);GO:1904872(regulation of telomerase RNA localization to Cajal body);GO:0003730(mRNA 3'-UTR binding);GO:0043169(cation binding);GO:0009451(RNA modification);GO:0090503(RNA phosphodiester bond hydrolysis, exonucleolytic);GO:0110008(ncRNA deadenylation)","03018(RNA degradation)","NA","NA","poly(A)-specific ribonuclease [Source:HGNC Symbol;Acc:HGNC:8609]",{"v":0.09349,"d":"0.09"},{"v":0.116379,"d":"0.12"},{"v":0.803323623677811,"d":"0.80"},{"v":-0.315946791805164,"d":"-0.32"},1,1,"down","no"]
[157772,0,"chr5","+",122816923,122829773,"ENST00000506847",6,798,"MSTRG.12271","SNX2","GO:0006810(transport);GO:0016020(membrane);GO:0006886(intracellular protein transport);GO:0015031(protein transport);GO:0005829(cytosol);GO:0006897(endocytosis);GO:0042995(cell projection);GO:0005515(protein binding);GO:0035091(phosphatidylinositol binding);GO:0005764(lysosome);GO:0005768(endosome);GO:0008289(lipid binding);GO:0034498(early endosome to Golgi transport);GO:0045296(cadherin binding);GO:0030027(lamellipodium);GO:0070062(extracellular exosome);GO:0043234(protein complex);GO:0019898(extrinsic component of membrane);GO:0010008(endosome membrane);GO:0042147(retrograde transport, endosome to Golgi);GO:0031901(early endosome membrane);GO:0030904(retromer complex);GO:0042803(protein homodimerization activity);GO:0046982(protein heterodimerization activity);GO:0005737(cytoplasm);GO:0051259(protein oligomerization);GO:0005154(epidermal growth factor receptor binding);GO:0005158(insulin receptor binding);GO:1990459(transferrin receptor binding);GO:1990460(leptin receptor binding);GO:0016050(vesicle organization);GO:0072673(lamellipodium morphogenesis);GO:0030905(retromer, tubulation complex);GO:0005622(intracellular)","04144(Endocytosis)","NA","NA","sorting nexin 2 [Source:HGNC Symbol;Acc:HGNC:11173]",{"v":0.152367,"d":"0.15"},0,"inf","inf",1,1,"up","no"]
[98899,0,"chr19","+",19339667,19344852,"ENST00000585823",7,568,"MSTRG.8017","MAU2","GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0051301(cell division);GO:0007049(cell cycle);GO:0016604(nuclear body);GO:0003690(double-stranded DNA binding);GO:0007059(chromosome segregation);GO:0005515(protein binding);GO:0007064(mitotic sister chromatid cohesion);GO:0047485(protein N-terminus binding);GO:0000785(chromatin);GO:0034088(maintenance of mitotic sister chromatid cohesion);GO:0032116(SMC loading complex)","NA","NA","NA","MAU2 sister chromatid cohesion factor [Source:HGNC Symbol;Acc:HGNC:29140]",0,0,1,0,1,1,"no","no"]
[132342,0,"chr22","-",47463467,47487088,"ENST00000481625",2,465,"ENSG00000218357","LINC01644","NA","NA","NA","NA","long intergenic non-protein coding RNA 1644 [Source:HGNC Symbol;Acc:HGNC:52431]",0,0,1,0,1,1,"no","no"]
[151274,0,"chr4","+",145375543,145376253,"ENST00000536295",1,711,"ENSG00000251333","RTN3P1","NA","NA","NA","NA","reticulon 3 pseudogene 1 [Source:HGNC Symbol;Acc:HGNC:19212]",{"v":0.134469,"d":"0.13"},{"v":0.425117,"d":"0.43"},{"v":0.316310568619933,"d":"0.32"},{"v":-1.66058633466645,"d":"-1.66"},1,1,"down","no"]
[113294,0,"chr2","+",108730817,108731898,"ENST00000495924",2,646,"MSTRG.9031","RANBP2","GO:0003723(RNA binding);GO:0006810(transport);GO:0051028(mRNA transport);GO:0005634(nucleus);GO:0016020(membrane);GO:0015031(protein transport);GO:0043231(intracellular membrane-bounded organelle);GO:0046872(metal ion binding);GO:0031965(nuclear membrane);GO:0003755(peptidyl-prolyl cis-trans isomerase activity);GO:0000413(protein peptidyl-prolyl isomerization);GO:0006457(protein folding);GO:0043547(positive regulation of GTPase activity);GO:0016874(ligase activity);GO:0005515(protein binding);GO:0046907(intracellular transport);GO:0005643(nuclear pore);GO:0005737(cytoplasm);GO:0005096(GTPase activator activity);GO:0005813(centrosome);GO:0005829(cytosol);GO:0075733(intracellular transport of virus);GO:0043657(host cell);GO:0006607(NLS-bearing protein import into nucleus);GO:0016925(protein sumoylation);GO:0007051(spindle organization);GO:0007062(sister chromatid cohesion);GO:0019789(SUMO transferase activity);GO:0005635(nuclear envelope);GO:0016032(viral process);GO:0005642(annulate lamellae);GO:0006406(mRNA export from nucleus);GO:0060964(regulation of gene silencing by miRNA);GO:0006110(regulation of glycolytic process);GO:0006409(tRNA export from nucleus);GO:0007077(mitotic nuclear envelope disassembly);GO:0019083(viral transcription);GO:1900034(regulation of cellular response to heat);GO:0006511(ubiquitin-dependent protein catabolic process);GO:0008536(Ran GTPase binding);GO:0042405(nuclear inclusion body);GO:0006405(RNA export from nucleus);GO:0000082(G1/S transition of mitotic cell cycle);GO:0044615(nuclear pore nuclear basket);GO:0051642(centrosome localization);GO:0046604(positive regulation of mitotic centrosome separation);GO:0032403(protein complex binding);GO:0001975(response to amphetamine);GO:0033133(positive regulation of glucokinase activity);GO:0090526(regulation of gluconeogenesis involved in cellular glucose homeostasis);GO:0005739(mitochondrion);GO:0044614(nuclear pore cytoplasmic filaments);GO:1990723(cytoplasmic periphery of the nuclear pore complex)","03013(RNA transport)","NA","NA","RAN binding protein 2 [Source:HGNC Symbol;Acc:HGNC:9848]",0,{"v":0.049573,"d":"0.05"},"-inf","-inf",1,1,"down","no"]
[48528,0,"chr12","+",131711081,131725609,"ENST00000540469",4,3536,"MSTRG.3873","SFSWAP","GO:0003723(RNA binding);GO:0006396(RNA processing);GO:0006397(mRNA processing);GO:0008380(RNA splicing);GO:0005634(nucleus);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0005515(protein binding);GO:0048025(negative regulation of mRNA splicing, via spliceosome);GO:0000395(mRNA 5'-splice site recognition);GO:0000380(alternative mRNA splicing, via spliceosome)","NA","NA","NA","splicing factor SWAP homolog [Source:HGNC Symbol;Acc:HGNC:10790]",0,0,1,0,1,1,"no","no"]
[62657,0,"chr15","+",52180093,52205334,"ENST00000559779",3,908,"ENSG00000259577","CERNA1","NA","NA","NA","NA","competing endogenous lncRNA 1 for miR-4707-5p and miR-4767 [Source:HGNC Symbol;Acc:HGNC:52664]",{"v":0.369695,"d":"0.37"},{"v":0.347204,"d":"0.35"},{"v":1.06477747952213,"d":"1.06"},{"v":0.0905519630967246,"d":"0.09"},1,1,"up","no"]
[95919,0,"chr19","-",8332745,8334430,"ENST00000610351",2,1193,"MSTRG.7762","KANK3","NA","NA","NA","NA","KN motif and ankyrin repeat domains 3 [Source:HGNC Symbol;Acc:HGNC:24796]",0,0,1,0,1,1,"no","no"]
[114233,0,"chr2","-",127638428,127664452,"ENST00000466410",9,2592,"ENSG00000072163","LIMS2","GO:0046872(metal ion binding);GO:0005925(focal adhesion);GO:0005634(nucleus);GO:0016020(membrane);GO:0005886(plasma membrane);GO:0030054(cell junction);GO:0005829(cytosol);GO:0034329(cell junction assembly);GO:0016337(single organismal cell-cell adhesion);GO:0043066(negative regulation of apoptotic process);GO:0045216(cell-cell junction organization);GO:0050680(negative regulation of epithelial cell proliferation);GO:2000178(negative regulation of neural precursor cell proliferation);GO:2000346(negative regulation of hepatocyte proliferation);GO:2001046(positive regulation of integrin-mediated signaling pathway)","NA","NA","NA","LIM zinc finger domain containing 2 [Source:HGNC Symbol;Acc:HGNC:16084]",0,{"v":0.069582,"d":"0.07"},"-inf","-inf",1,1,"down","no"]
[187037,0,"chr8","+",125432209,125436928,"ENST00000520847",3,1332,"MSTRG.14546","TRIB1","GO:0005737(cytoplasm);GO:0043433(negative regulation of sequence-specific DNA binding transcription factor activity);GO:0005634(nucleus);GO:0048662(negative regulation of smooth muscle cell proliferation);GO:0005515(protein binding);GO:0004860(protein kinase inhibitor activity);GO:0032496(response to lipopolysaccharide);GO:0006469(negative regulation of protein kinase activity);GO:0032436(positive regulation of proteasomal ubiquitin-dependent protein catabolic process);GO:0043405(regulation of MAP kinase activity);GO:0031625(ubiquitin protein ligase binding);GO:0008134(transcription factor binding);GO:0014912(negative regulation of smooth muscle cell migration);GO:0031434(mitogen-activated protein kinase kinase binding);GO:0055106(ubiquitin-protein transferase regulator activity);GO:0007254(JNK cascade);GO:0031665(negative regulation of lipopolysaccharide-mediated signaling pathway);GO:0045645(positive regulation of eosinophil differentiation);GO:0045651(positive regulation of macrophage differentiation);GO:0045659(negative regulation of neutrophil differentiation);GO:0004672(protein kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation)","NA","NA","NA","tribbles pseudokinase 1 [Source:HGNC Symbol;Acc:HGNC:16891]",0,0,1,0,1,1,"no","no"]
[128499,0,"chr22","-",19180733,19291661,"ENST00000615606",30,4994,"ENSG00000070371","CLTCL1","GO:0016020(membrane);GO:0006886(intracellular protein transport);GO:0016192(vesicle-mediated transport);GO:0005198(structural molecule activity);GO:0030659(cytoplasmic vesicle membrane);GO:0031410(cytoplasmic vesicle);GO:0048268(clathrin coat assembly);GO:0005905(clathrin-coated pit);GO:0030130(clathrin coat of trans-Golgi network vesicle);GO:0007165(signal transduction);GO:0005819(spindle);GO:0032051(clathrin light chain binding);GO:0071439(clathrin complex);GO:0005515(protein binding);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0061024(membrane organization);GO:0005802(trans-Golgi network);GO:0042147(retrograde transport, endosome to Golgi);GO:0005770(late endosome);GO:0004871(signal transducer activity);GO:0030136(clathrin-coated vesicle);GO:0009653(anatomical structure morphogenesis);GO:0000278(mitotic cell cycle);GO:0006898(receptor-mediated endocytosis);GO:0046326(positive regulation of glucose import);GO:0030135(coated vesicle);GO:0097443(sorting endosome);GO:0005622(intracellular);GO:0030132(clathrin coat of coated pit)","04144(Endocytosis);04142(Lysosome);04961(Endocrine and other factor-regulated calcium reabsorption);04721(Synaptic vesicle cycle);05016(Huntington's disease);05100(Bacterial invasion of epithelial cells)","NA","NA","clathrin heavy chain like 1 [Source:HGNC Symbol;Acc:HGNC:2093]",0,{"v":0.383314,"d":"0.38"},"-inf","-inf",1,1,"down","no"]
[89738,0,"chr17","-",82079222,82079378,"ENST00000636628",2,100,"MSTRG.7349","FASN","GO:0003723(RNA binding);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005794(Golgi apparatus);GO:0005829(cytosol);GO:0016740(transferase activity);GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0016787(hydrolase activity);GO:0003824(catalytic activity);GO:0016829(lyase activity);GO:0006629(lipid metabolic process);GO:0008152(metabolic process);GO:0009058(biosynthetic process);GO:0005886(plasma membrane);GO:0006631(fatty acid metabolic process);GO:0006633(fatty acid biosynthetic process);GO:0005515(protein binding);GO:0042470(melanosome);GO:0016788(hydrolase activity, acting on ester bonds);GO:0004315(3-oxoacyl-[acyl-carrier-protein] synthase activity);GO:0004312(fatty acid synthase activity);GO:0004313([acyl-carrier-protein] S-acetyltransferase activity);GO:0004314([acyl-carrier-protein] S-malonyltransferase activity);GO:0004316(3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity);GO:0004317(3-hydroxypalmitoyl-[acyl-carrier-protein] dehydratase activity);GO:0004319(enoyl-[acyl-carrier-protein] reductase (NADPH, B-specific) activity);GO:0004320(oleoyl-[acyl-carrier-protein] hydrolase activity);GO:0016295(myristoyl-[acyl-carrier-protein] hydrolase activity);GO:0016296(palmitoyl-[acyl-carrier-protein] hydrolase activity);GO:0016297(acyl-[acyl-carrier-protein] hydrolase activity);GO:0031177(phosphopantetheine binding);GO:0045296(cadherin binding);GO:0070062(extracellular exosome);GO:0031325(positive regulation of cellular metabolic process);GO:0045540(regulation of cholesterol biosynthetic process);GO:0046949(fatty-acyl-CoA biosynthetic process);GO:0001649(osteoblast differentiation);GO:0015939(pantothenate metabolic process);GO:0008144(drug binding);GO:0019171(3-hydroxyacyl-[acyl-carrier-protein] dehydratase activity);GO:0042802(identical protein binding);GO:0042803(protein homodimerization activity);GO:0047117(enoyl-[acyl-carrier-protein] reductase (NADPH, A-specific) activity);GO:0047451(3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity);GO:0070402(NADPH binding);GO:0102131(3-oxo-glutaryl-[acp] methyl ester reductase activity);GO:0102132(3-oxo-pimeloyl-[acp] methyl ester reductase activity);GO:0006084(acetyl-CoA metabolic process);GO:0030879(mammary gland development);GO:0071353(cellular response to interleukin-4);GO:0005739(mitochondrion);GO:0042587(glycogen granule)","00061(Fatty acid biosynthesis);04152(AMPK signaling pathway);04910(Insulin signaling pathway)","NA","NA","fatty acid synthase [Source:HGNC Symbol;Acc:HGNC:3594]",{"v":0.032555,"d":"0.03"},0,"inf","inf",1,1,"up","no"]
[73448,0,"chr16","+",57129052,57147966,"ENST00000566910",5,938,"MSTRG.5943","CPNE2","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0070062(extracellular exosome);GO:0071277(cellular response to calcium ion)","NA","NA","NA","copine 2 [Source:HGNC Symbol;Acc:HGNC:2315]",{"v":0.255443,"d":"0.26"},{"v":1.080306,"d":"1.08"},{"v":0.236454300911038,"d":"0.24"},{"v":-2.0803667114059,"d":"-2.08"},1,1,"down","no"]
[89357,0,"chr17","-",81559125,81566635,"ENST00000573876",3,560,"MSTRG.7324","NPLOC4","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0005829(cytosol);GO:0005783(endoplasmic reticulum);GO:0005515(protein binding);GO:0006511(ubiquitin-dependent protein catabolic process);GO:0031625(ubiquitin protein ligase binding);GO:0030970(retrograde protein transport, ER to cytosol);GO:0005654(nucleoplasm);GO:0032480(negative regulation of type I interferon production);GO:0043130(ubiquitin binding);GO:0043161(proteasome-mediated ubiquitin-dependent protein catabolic process);GO:0070987(error-free translesion synthesis);GO:0034098(VCP-NPL4-UFD1 AAA ATPase complex);GO:0039536(negative regulation of RIG-I signaling pathway);GO:0007030(Golgi organization);GO:0030433(ubiquitin-dependent ERAD pathway);GO:0036501(UFD1-NPL4 complex);GO:0042175(nuclear outer membrane-endoplasmic reticulum membrane network)","04141(Protein processing in endoplasmic reticulum)","NA","NA","NPL4 homolog, ubiquitin recognition factor [Source:HGNC Symbol;Acc:HGNC:18261]",{"v":0.000209,"d":"0.00"},{"v":0.078154,"d":"0.08"},{"v":0.00267420733423753,"d":"0.00"},{"v":-8.54667296116035,"d":"-8.55"},1,1,"down","no"]
[54072,0,"chr14","+",31248628,31302739,"ENST00000551799",6,975,"ENSG00000257831","AL136418.1","NA","NA","NA","NA","NA",{"v":0.024169,"d":"0.02"},0,"inf","inf",1,1,"up","no"]
[183525,0,"chr8","+",42896946,42998156,"ENST00000527306",16,2325,"MSTRG.14338","HOOK3","GO:0006810(transport);GO:0005737(cytoplasm);GO:0015031(protein transport);GO:0005829(cytosol);GO:0005794(Golgi apparatus);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0005874(microtubule);GO:0008017(microtubule binding);GO:0005813(centrosome);GO:0008333(endosome to lysosome transport);GO:0051959(dynein light intermediate chain binding);GO:0030705(cytoskeleton-dependent intracellular transport);GO:0042802(identical protein binding);GO:0051645(Golgi localization);GO:0050768(negative regulation of neurogenesis);GO:0007040(lysosome organization);GO:0005801(cis-Golgi network);GO:0007032(endosome organization);GO:0000242(pericentriolar material);GO:0045022(early endosome to late endosome transport);GO:0030897(HOPS complex);GO:0022027(interkinetic nuclear migration);GO:0031122(cytoplasmic microtubule organization);GO:0071539(protein localization to centrosome);GO:0034454(microtubule anchoring at centrosome);GO:0097150(neuronal stem cell population maintenance);GO:0034451(centriolar satellite);GO:0070695(FHF complex)","NA","NA","NA","hook microtubule tethering protein 3 [Source:HGNC Symbol;Acc:HGNC:23576]",{"v":0.790334,"d":"0.79"},{"v":0.019558,"d":"0.02"},{"v":40.409755598732,"d":"40.41"},{"v":5.33663172090605,"d":"5.34"},1,1,"up","no"]
[190164,0,"chr9","+",36190963,36212059,"ENST00000396603",6,1090,"MSTRG.14764","CLTA","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0006886(intracellular protein transport);GO:0016192(vesicle-mediated transport);GO:0051301(cell division);GO:0005198(structural molecule activity);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0007049(cell cycle);GO:0030659(cytoplasmic vesicle membrane);GO:0031410(cytoplasmic vesicle);GO:0005905(clathrin-coated pit);GO:0030130(clathrin coat of trans-Golgi network vesicle);GO:0030132(clathrin coat of coated pit);GO:0005819(spindle);GO:0005886(plasma membrane);GO:0003674(molecular_function);GO:0005829(cytosol);GO:0061024(membrane organization);GO:0007018(microtubule-based movement);GO:0019886(antigen processing and presentation of exogenous peptide antigen via MHC class II);GO:0032588(trans-Golgi network membrane);GO:0034383(low-density lipoprotein particle clearance);GO:0036020(endolysosome membrane);GO:0032802(low-density lipoprotein particle receptor catabolic process);GO:0032050(clathrin heavy chain binding);GO:0048268(clathrin coat assembly);GO:0072583(clathrin-dependent endocytosis);GO:0030118(clathrin coat);GO:0030125(clathrin vesicle coat);GO:0071439(clathrin complex);GO:0032403(protein complex binding);GO:0042277(peptide binding);GO:0051020(GTPase binding);GO:0006897(endocytosis);GO:0030136(clathrin-coated vesicle);GO:0030672(synaptic vesicle membrane)","04144(Endocytosis);04142(Lysosome);04961(Endocrine and other factor-regulated calcium reabsorption);04721(Synaptic vesicle cycle);05016(Huntington's disease);05100(Bacterial invasion of epithelial cells)","K04644","NA","clathrin light chain A [Source:HGNC Symbol;Acc:HGNC:2090]",0,0,1,0,1,1,"no","no"]
[108715,0,"chr2","-",36552258,36559255,"ENST00000475815",2,4495,"MSTRG.8621","FEZ2","GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0007399(nervous system development);GO:0007165(signal transduction);GO:0007411(axon guidance);GO:0030424(axon);GO:1902902(negative regulation of autophagosome assembly)","NA","NA","NA","fasciculation and elongation protein zeta 2 [Source:HGNC Symbol;Acc:HGNC:3660]",{"v":0.084927,"d":"0.08"},{"v":0.037994,"d":"0.04"},{"v":2.2352739906301,"d":"2.24"},{"v":1.16045168183191,"d":"1.16"},1,1,"up","no"]
[128805,0,"chr22","+",20550987,20564597,"ENST00000457322",5,623,"MSTRG.10158","MED15","GO:0005634(nucleus);GO:0001104(RNA polymerase II transcription cofactor activity);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0016592(mediator complex);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0005515(protein binding);GO:0005654(nucleoplasm);GO:0006367(transcription initiation from RNA polymerase II promoter)","NA","NA","NA","mediator complex subunit 15 [Source:HGNC Symbol;Acc:HGNC:14248]",{"v":0.05675,"d":"0.06"},0,"inf","inf",1,1,"up","no"]
[120882,0,"chr2","+",240560792,240564014,"ENST00000438823",3,817,"MSTRG.9515","DUSP28","GO:0016787(hydrolase activity);GO:0008138(protein tyrosine/serine/threonine phosphatase activity);GO:0016791(phosphatase activity);GO:0006470(protein dephosphorylation);GO:0016311(dephosphorylation);GO:0004721(phosphoprotein phosphatase activity);GO:0004725(protein tyrosine phosphatase activity);GO:0035335(peptidyl-tyrosine dephosphorylation)","NA","NA","NA","dual specificity phosphatase 28 [Source:HGNC Symbol;Acc:HGNC:33237]",0,{"v":0.75013,"d":"0.75"},"-inf","-inf",1,1,"down","no"]
[29611,0,"chr11","+",59755398,59805882,"ENST00000633708",11,3111,"MSTRG.2420","STX3","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0006886(intracellular protein transport);GO:0016192(vesicle-mediated transport);GO:0006887(exocytosis);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0016081(synaptic vesicle docking);GO:0005484(SNAP receptor activity);GO:0030027(lamellipodium);GO:0070062(extracellular exosome);GO:0000149(SNARE binding);GO:0031201(SNARE complex);GO:0008284(positive regulation of cell proliferation);GO:0048278(vesicle docking);GO:0031629(synaptic vesicle fusion to presynaptic active zone membrane);GO:0042581(specific granule);GO:0042582(azurophil granule);GO:0045785(positive regulation of cell adhesion);GO:0005911(cell-cell junction);GO:0006836(neurotransmitter transport);GO:0008021(synaptic vesicle);GO:0050921(positive regulation of chemotaxis);GO:2000010(positive regulation of protein localization to cell surface);GO:0030426(growth cone);GO:0043005(neuron projection);GO:1903078(positive regulation of protein localization to plasma membrane);GO:0005773(vacuole);GO:0050544(arachidonic acid binding);GO:0006906(vesicle fusion);GO:0031175(neuron projection development);GO:0060291(long-term synaptic potentiation);GO:0061025(membrane fusion);GO:0098967(exocytic insertion of neurotransmitter receptor to postsynaptic membrane);GO:0016324(apical plasma membrane);GO:0030141(secretory granule);GO:0030425(dendrite);GO:0042470(melanosome);GO:0042589(zymogen granule membrane);GO:0042734(presynaptic membrane);GO:0097470(ribbon synapse);GO:0098794(postsynapse);GO:1990796(photoreceptor cell terminal bouton);GO:0005622(intracellular);GO:0098793(presynapse)","04130(SNARE interactions in vesicular transport);04721(Synaptic vesicle cycle)","K08486","NA","syntaxin 3 [Source:HGNC Symbol;Acc:HGNC:11438]",{"v":0.209133,"d":"0.21"},0,"inf","inf",1,1,"up","no"]
[37621,0,"chr12","+",4562204,4613874,"ENST00000543431",15,2068,"ENSG00000010219","DYRK4","GO:0043231(intracellular membrane-bounded organelle);GO:0004672(protein kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0004674(protein serine/threonine kinase activity);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0004713(protein tyrosine kinase activity);GO:0018108(peptidyl-tyrosine phosphorylation);GO:0005515(protein binding);GO:0004712(protein serine/threonine/tyrosine kinase activity)","NA","NA","NA","dual specificity tyrosine phosphorylation regulated kinase 4 [Source:HGNC Symbol;Acc:HGNC:3095]",{"v":0.123643,"d":"0.12"},{"v":0.488089,"d":"0.49"},{"v":0.253320603414541,"d":"0.25"},{"v":-1.98096367383712,"d":"-1.98"},1,1,"down","no"]
[158637,0,"chr5","+",136160986,136172829,"ENST00000507637",3,638,"ENSG00000113658","SMAD5","GO:0005737(cytoplasm);GO:0005634(nucleus);GO:0030509(BMP signaling pathway);GO:0016021(integral component of membrane);GO:0046872(metal ion binding);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding);GO:0005622(intracellular);GO:0007165(signal transduction);GO:0007179(transforming growth factor beta receptor signaling pathway);GO:0005667(transcription factor complex);GO:0045893(positive regulation of transcription, DNA-templated);GO:0005515(protein binding);GO:0043234(protein complex);GO:0031625(ubiquitin protein ligase binding);GO:0030618(transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity);GO:0060395(SMAD protein signal transduction);GO:1901522(positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus);GO:0071141(SMAD protein complex);GO:0005057(signal transducer activity, downstream of receptor);GO:0009880(embryonic pattern specification);GO:0017151(DEAD/H-box RNA helicase binding);GO:0000977(RNA polymerase II regulatory region sequence-specific DNA binding);GO:0000979(RNA polymerase II core promoter sequence-specific DNA binding);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0001503(ossification);GO:0001657(ureteric bud development);GO:0001880(Mullerian duct regression);GO:0002051(osteoblast fate commitment);GO:0006468(protein phosphorylation);GO:0007281(germ cell development);GO:0030218(erythrocyte differentiation);GO:0045669(positive regulation of osteoblast differentiation);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0051216(cartilage development);GO:0060048(cardiac muscle contraction);GO:0060348(bone development);GO:0071407(cellular response to organic cyclic compound);GO:0071773(cellular response to BMP stimulus)","04350(TGF-beta signaling pathway);04550(Signaling pathways regulating pluripotency of stem cells)","NA","NA","SMAD family member 5 [Source:HGNC Symbol;Acc:HGNC:6771]",0,{"v":0.077368,"d":"0.08"},"-inf","-inf",1,1,"down","no"]
[41994,0,"chr12","-",53014629,53046959,"ENST00000552905",3,523,"MSTRG.3389","AC068888.1","NA","NA","NA","NA","NA",0,0,1,0,1,1,"no","no"]
[75173,0,"chr16","+",70299178,70319709,"ENST00000562912",5,569,"MSTRG.6093","DDX19B","GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0006810(transport);GO:0051028(mRNA transport);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0015031(protein transport);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0016787(hydrolase activity);GO:0004386(helicase activity);GO:0005515(protein binding);GO:0005643(nuclear pore);GO:0005730(nucleolus);GO:0070062(extracellular exosome);GO:0004004(ATP-dependent RNA helicase activity);GO:0010501(RNA secondary structure unwinding);GO:0010468(regulation of gene expression);GO:0031965(nuclear membrane);GO:0008380(RNA splicing);GO:0071013(catalytic step 2 spliceosome);GO:0006406(mRNA export from nucleus)","NA","NA","NA","DEAD-box helicase 19B [Source:HGNC Symbol;Acc:HGNC:2742]",0,0,1,0,1,1,"no","no"]
[50168,0,"chr13","-",46152781,46168519,"ENST00000416500",7,819,"MSTRG.3990","LCP1","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0046872(metal ion binding);GO:0005829(cytosol);GO:0005509(calcium ion binding);GO:0003779(actin binding);GO:0005886(plasma membrane);GO:0015629(actin cytoskeleton);GO:0005856(cytoskeleton);GO:0042995(cell projection);GO:0005615(extracellular space);GO:0030054(cell junction);GO:0005925(focal adhesion);GO:0042802(identical protein binding);GO:0051015(actin filament binding);GO:0031100(animal organ regeneration);GO:0051017(actin filament bundle assembly);GO:0001726(ruffle);GO:0001891(phagocytic cup);GO:0005884(actin filament);GO:0030175(filopodium);GO:0070062(extracellular exosome);GO:0022617(extracellular matrix disassembly);GO:0002102(podosome);GO:0001725(stress fiber);GO:0032587(ruffle membrane);GO:0035722(interleukin-12-mediated signaling pathway);GO:0016477(cell migration);GO:0051639(actin filament network formation);GO:0051020(GTPase binding);GO:0032432(actin filament bundle);GO:0002286(T cell activation involved in immune response);GO:0010737(protein kinase A signaling);GO:0033157(regulation of intracellular protein transport);GO:0051764(actin crosslink formation);GO:0071803(positive regulation of podosome assembly)","NA","NA","NA","lymphocyte cytosolic protein 1 [Source:HGNC Symbol;Acc:HGNC:6528]",{"v":0.116054,"d":"0.12"},{"v":0.085506,"d":"0.09"},{"v":1.35726147872664,"d":"1.36"},{"v":0.440698685180124,"d":"0.44"},1,1,"up","no"]
[42519,0,"chr12","+",54574757,54577236,"ENST00000552774",5,796,"ENSG00000123360","PDE1B","GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0005634(nucleus);GO:0005829(cytosol);GO:0016787(hydrolase activity);GO:0007165(signal transduction);GO:0005515(protein binding);GO:0008081(phosphoric diester hydrolase activity);GO:0004112(cyclic-nucleotide phosphodiesterase activity);GO:0004114(3',5'-cyclic-nucleotide phosphodiesterase activity);GO:0004115(3',5'-cyclic-AMP phosphodiesterase activity);GO:0048101(calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity);GO:0001505(regulation of neurotransmitter levels);GO:0001975(response to amphetamine);GO:0006198(cAMP catabolic process);GO:0007626(locomotory behavior);GO:0008542(visual learning);GO:0042053(regulation of dopamine metabolic process);GO:0042428(serotonin metabolic process);GO:0046069(cGMP catabolic process);GO:0043025(neuronal cell body);GO:0005516(calmodulin binding);GO:0006915(apoptotic process);GO:0047555(3',5'-cyclic-GMP phosphodiesterase activity);GO:0036006(cellular response to macrophage colony-stimulating factor stimulus);GO:0030224(monocyte differentiation);GO:0097011(cellular response to granulocyte macrophage colony-stimulating factor stimulus);GO:0004117(calmodulin-dependent cyclic-nucleotide phosphodiesterase activity)","00230(Purine metabolism);04020(Calcium signaling pathway);04924(Renin secretion);04740(Olfactory transduction);04742(Taste transduction);05032(Morphine addiction)","NA","NA","phosphodiesterase 1B [Source:HGNC Symbol;Acc:HGNC:8775]",0,{"v":0.440871,"d":"0.44"},"-inf","-inf",1,1,"down","no"]
[33128,0,"chr11","-",74909919,74949075,"ENST00000533598",8,872,"MSTRG.2710","XRRA1","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005654(nucleoplasm);GO:0016604(nuclear body);GO:0003674(molecular_function);GO:0010165(response to X-ray)","NA","NA","NA","X-ray radiation resistance associated 1 [Source:HGNC Symbol;Acc:HGNC:18868]",0,0,1,0,1,1,"no","no"]
[88803,0,"chr17","+",78342737,78344357,"ENST00000586583",2,643,"ENSG00000267737","AC087645.2","NA","NA","NA","NA","NA",0,{"v":0.172684,"d":"0.17"},"-inf","-inf",1,1,"down","no"]
[70815,0,"chr16","-",23474953,23480423,"ENST00000569182",5,587,"MSTRG.5751","GGA2","GO:0006810(transport);GO:0016020(membrane);GO:0006886(intracellular protein transport);GO:0015031(protein transport);GO:0016192(vesicle-mediated transport);GO:0005794(Golgi apparatus);GO:0005622(intracellular);GO:0030131(clathrin adaptor complex);GO:0005515(protein binding);GO:0005768(endosome);GO:0044267(cellular protein metabolic process);GO:0061024(membrane organization);GO:0005802(trans-Golgi network);GO:0010008(endosome membrane);GO:0030136(clathrin-coated vesicle);GO:0030306(ADP-ribosylation factor binding);GO:0031901(early endosome membrane)","04142(Lysosome)","NA","NA","golgi associated, gamma adaptin ear containing, ARF binding protein 2 [Source:HGNC Symbol;Acc:HGNC:16064]",0,0,1,0,1,1,"no","no"]
[68094,0,"chr16","-",1963212,1964841,"ENST00000563194",3,170,"MSTRG.5529","RPS2","GO:0003723(RNA binding);GO:0005634(nucleus);GO:0016020(membrane);GO:0006412(translation);GO:0030529(intracellular ribonucleoprotein complex);GO:0003735(structural constituent of ribosome);GO:0005840(ribosome);GO:0015935(small ribosomal subunit);GO:0005515(protein binding);GO:0022627(cytosolic small ribosomal subunit);GO:0005654(nucleoplasm);GO:0005925(focal adhesion);GO:0003729(mRNA binding);GO:0005829(cytosol);GO:0045296(cadherin binding);GO:0070062(extracellular exosome);GO:0019899(enzyme binding);GO:0006413(translational initiation);GO:0006364(rRNA processing);GO:0000184(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay);GO:0019083(viral transcription);GO:0006479(protein methylation);GO:0006614(SRP-dependent cotranslational protein targeting to membrane);GO:0017134(fibroblast growth factor binding);GO:0051347(positive regulation of transferase activity)","03010(Ribosome)","NA","NA","ribosomal protein S2 [Source:HGNC Symbol;Acc:HGNC:10404]",{"v":0.397766,"d":"0.40"},0,"inf","inf",1,1,"up","no"]
[25870,0,"chr11","+",5402597,5403547,"ENST00000332043",1,951,"MSTRG.2165","OR51J1","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0004930(G-protein coupled receptor activity);GO:0007186(G-protein coupled receptor signaling pathway);GO:0005886(plasma membrane);GO:0004871(signal transducer activity);GO:0007165(signal transduction);GO:0004984(olfactory receptor activity);GO:0007608(sensory perception of smell);GO:0050896(response to stimulus);GO:0050911(detection of chemical stimulus involved in sensory perception of smell)","NA","NA","NA","olfactory receptor family 51 subfamily J member 1 (gene/pseudogene) [Source:HGNC Symbol;Acc:HGNC:14856]",{"v":0.108101,"d":"0.11"},0,"inf","inf",1,1,"up","no"]
[122799,0,"chr20","-",31664452,31722597,"ENST00000376062",2,2578,"MSTRG.9635","BCL2L1","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005743(mitochondrial inner membrane);GO:0042981(regulation of apoptotic process);GO:0005829(cytosol);GO:0005739(mitochondrion);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0006915(apoptotic process);GO:0030054(cell junction);GO:0045202(synapse);GO:0005741(mitochondrial outer membrane);GO:0031410(cytoplasmic vesicle);GO:0005759(mitochondrial matrix);GO:0005813(centrosome);GO:0005815(microtubule organizing center);GO:0042802(identical protein binding);GO:0006897(endocytosis);GO:0019901(protein kinase binding);GO:0051434(BH3 domain binding);GO:0043066(negative regulation of apoptotic process);GO:0031965(nuclear membrane);GO:0030672(synaptic vesicle membrane);GO:0000910(cytokinesis);GO:2001240(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand);GO:0042803(protein homodimerization activity);GO:1902042(negative regulation of extrinsic apoptotic signaling pathway via death domain receptors);GO:0007093(mitotic cell cycle checkpoint);GO:2001244(positive regulation of intrinsic apoptotic signaling pathway);GO:1902230(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage);GO:0090201(negative regulation of release of cytochrome c from mitochondria);GO:0001836(release of cytochrome c from mitochondria);GO:1900118(negative regulation of execution phase of apoptosis);GO:0034097(response to cytokine);GO:0046902(regulation of mitochondrial membrane permeability);GO:0051881(regulation of mitochondrial membrane potential);GO:0046982(protein heterodimerization activity);GO:0090005(negative regulation of establishment of protein localization to plasma membrane);GO:0008637(apoptotic mitochondrial changes);GO:0097136(Bcl-2 family protein complex);GO:0019050(suppression by virus of host apoptotic process);GO:2001243(negative regulation of intrinsic apoptotic signaling pathway);GO:0001541(ovarian follicle development);GO:0001701(in utero embryonic development);GO:0007281(germ cell development);GO:0007283(spermatogenesis);GO:0008283(cell proliferation);GO:0008284(positive regulation of cell proliferation);GO:0008584(male gonad development);GO:0008630(intrinsic apoptotic signaling pathway in response to DNA damage);GO:0009314(response to radiation);GO:0009566(fertilization);GO:0009615(response to virus);GO:0040007(growth);GO:0043065(positive regulation of apoptotic process);GO:0043524(negative regulation of neuron apoptotic process);GO:0046898(response to cycloheximide);GO:0051402(neuron apoptotic process);GO:0060154(cellular process regulating host cell cycle in response to virus);GO:0070584(mitochondrion morphogenesis);GO:0071230(cellular response to amino acid stimulus);GO:0071312(cellular response to alkaloid);GO:0071480(cellular response to gamma radiation);GO:0071839(apoptotic process in bone marrow);GO:0097192(extrinsic apoptotic signaling pathway in absence of ligand);GO:0097284(hepatocyte apoptotic process);GO:0005622(intracellular);GO:0005783(endoplasmic reticulum);GO:0031966(mitochondrial membrane)","04014(Ras signaling pathway);04630(Jak-STAT signaling pathway);04064(NF-kappa B signaling pathway);04151(PI3K-Akt signaling pathway);04140(Autophagy - animal);04137(Mitophagy - animal);04210(Apoptosis);04215(Apoptosis - multiple species);04621(NOD-like receptor signaling pathway);05200(Pathways in cancer);05202(Transcriptional misregulation in cancers);05212(Pancreatic cancer);05225(Hepatocellular carcinoma);05220(Chronic myeloid leukemia);05222(Small cell lung cancer);05014(Amyotrophic lateral sclerosis (ALS));05166(HTLV-I infection);05145(Toxoplasmosis);01521(EGFR tyrosine kinase inhibitor resistance);01524(Platinum drug resistance)","K04570","NA","BCL2 like 1 [Source:HGNC Symbol;Acc:HGNC:992]",{"v":1.382267,"d":"1.38"},{"v":4e-05,"d":"0.00"},{"v":34556.675,"d":"34556.68"},{"v":15.0766767894182,"d":"15.08"},1,1,"up","no"]
[88713,0,"chr17","-",78112922,78113959,"ENST00000590494",2,702,"MSTRG.7280","TMC6","GO:0006810(transport);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005794(Golgi apparatus);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0006811(ion transport);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0008150(biological_process);GO:0070062(extracellular exosome);GO:0043312(neutrophil degranulation);GO:0035579(specific granule membrane);GO:0070821(tertiary granule membrane);GO:0031965(nuclear membrane)","NA","NA","NA","transmembrane channel like 6 [Source:HGNC Symbol;Acc:HGNC:18021]",{"v":0.40513,"d":"0.41"},{"v":0.342227,"d":"0.34"},{"v":1.18380490142508,"d":"1.18"},{"v":0.243431335241281,"d":"0.24"},1,1,"up","no"]
[107591,0,"chr2","-",19352012,19356912,"ENST00000487581",2,4171,"ENSG00000143867","OSR1","GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0010628(positive regulation of gene expression);GO:0007507(heart development);GO:0030154(cell differentiation);GO:0048863(stem cell differentiation);GO:0043066(negative regulation of apoptotic process);GO:0030501(positive regulation of bone mineralization);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0005515(protein binding);GO:0005829(cytosol);GO:0060021(palate development);GO:0030857(negative regulation of epithelial cell differentiation);GO:0035115(embryonic forelimb morphogenesis);GO:0035116(embryonic hindlimb morphogenesis);GO:0042733(embryonic digit morphogenesis);GO:0072498(embryonic skeletal joint development);GO:0001823(mesonephros development);GO:0050679(positive regulation of epithelial cell proliferation);GO:0042474(middle ear morphogenesis);GO:0072162(metanephric mesenchymal cell differentiation);GO:0019901(protein kinase binding);GO:0004674(protein serine/threonine kinase activity);GO:0001657(ureteric bud development);GO:0018107(peptidyl-threonine phosphorylation);GO:0060272(embryonic skeletal joint morphogenesis);GO:0042476(odontogenesis);GO:0072075(metanephric mesenchyme development);GO:0072166(posterior mesonephric tubule development);GO:0072207(metanephric epithelium development);GO:0001655(urogenital system development);GO:2000543(positive regulation of gastrulation);GO:0036023(embryonic skeletal limb joint morphogenesis);GO:0048793(pronephros development);GO:0019898(extrinsic component of membrane);GO:0072208(metanephric smooth muscle tissue development);GO:0002062(chondrocyte differentiation);GO:0001656(metanephros development);GO:0007231(osmosensory signaling pathway);GO:0008406(gonad development);GO:0023016(signal transduction by trans-phosphorylation);GO:0048389(intermediate mesoderm development);GO:0071300(cellular response to retinoic acid);GO:0072111(cell proliferation involved in kidney development);GO:0072133(metanephric mesenchyme morphogenesis);GO:0072143(mesangial cell development);GO:0072168(specification of anterior mesonephric tubule identity);GO:0072169(specification of posterior mesonephric tubule identity);GO:0072180(mesonephric duct morphogenesis);GO:0072183(negative regulation of nephron tubule epithelial cell differentiation);GO:0072184(renal vesicle progenitor cell differentiation);GO:0072190(ureter urothelium development);GO:0072234(metanephric nephron tubule development);GO:0072239(metanephric glomerulus vasculature development);GO:0072259(metanephric interstitial fibroblast development);GO:0072268(pattern specification involved in metanephros development);GO:0090094(metanephric cap mesenchymal cell proliferation involved in metanephros development);GO:1905408(negative regulation of creatine transmembrane transporter activity);GO:2000650(negative regulation of sodium ion transmembrane transporter activity)","NA","NA","NA","odd-skipped related transciption factor 1 [Source:HGNC Symbol;Acc:HGNC:8111]",{"v":0.012324,"d":"0.01"},0,"inf","inf",1,1,"up","no"]
[188733,0,"chr9","+",2068953,2193624,"ENST00000635739",26,4272,"MSTRG.14677","SMARCA2","GO:0016514(SWI/SNF complex);GO:0016887(ATPase activity);GO:0006338(chromatin remodeling);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0005634(nucleus);GO:0043231(intracellular membrane-bounded organelle);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0005654(nucleoplasm);GO:0006355(regulation of transcription, DNA-templated);GO:0016787(hydrolase activity);GO:0006351(transcription, DNA-templated);GO:0004386(helicase activity);GO:0003677(DNA binding);GO:0045111(intermediate filament cytoskeleton);GO:0005515(protein binding);GO:0007399(nervous system development);GO:0045893(positive regulation of transcription, DNA-templated);GO:0042393(histone binding);GO:0016817(hydrolase activity, acting on acid anhydrides);GO:0008285(negative regulation of cell proliferation);GO:0003713(transcription coactivator activity);GO:0044212(transcription regulatory region DNA binding);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0000790(nuclear chromatin);GO:0045892(negative regulation of transcription, DNA-templated);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0071564(npBAF complex);GO:0071565(nBAF complex);GO:0001105(RNA polymerase II transcription coactivator activity);GO:0030308(negative regulation of cell growth);GO:0008094(DNA-dependent ATPase activity);GO:0003682(chromatin binding);GO:0007286(spermatid development)","05225(Hepatocellular carcinoma)","NA","NA","SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 [Source:HGNC Symbol;Acc:HGNC:11098]",0,{"v":5.2e-05,"d":"0.00"},"-inf","-inf",1,1,"down","no"]
[103753,0,"chr19","+",49086480,49098459,"ENST00000601411",5,377,"MSTRG.8303","SNRNP70","GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0006397(mRNA processing);GO:0005634(nucleus);GO:0016607(nuclear speck);GO:0005654(nucleoplasm);GO:0030529(intracellular ribonucleoprotein complex);GO:0030619(U1 snRNA binding);GO:0005515(protein binding);GO:0005681(spliceosomal complex);GO:0005685(U1 snRNP);GO:0003729(mRNA binding);GO:0043484(regulation of RNA splicing);GO:0000398(mRNA splicing, via spliceosome);GO:0008380(RNA splicing);GO:0071011(precatalytic spliceosome);GO:0071004(U2-type prespliceosome);GO:0043462(regulation of ATPase activity);GO:0061084(negative regulation of protein refolding);GO:1904715(negative regulation of chaperone-mediated autophagy);GO:0000243(commitment complex);GO:0019013(viral nucleocapsid);GO:1990446(U1 snRNP binding);GO:0048026(positive regulation of mRNA splicing, via spliceosome);GO:0071300(cellular response to retinoic acid);GO:0071356(cellular response to tumor necrosis factor);GO:0071560(cellular response to transforming growth factor beta stimulus);GO:0005737(cytoplasm)","03040(Spliceosome)","NA","NA","small nuclear ribonucleoprotein U1 subunit 70 [Source:HGNC Symbol;Acc:HGNC:11150]",{"v":0.900468,"d":"0.90"},{"v":0.822916,"d":"0.82"},{"v":1.09424048141001,"d":"1.09"},{"v":0.129929834301564,"d":"0.13"},1,1,"up","no"]
[1631,0,"chr1","+",11843861,11848079,"ENST00000400892",3,936,"ENSG00000242349","NPPA-AS1","NA","NA","NA","NA","NPPA antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:37635]",0,{"v":0.617491,"d":"0.62"},"-inf","-inf",1,1,"down","no"]
[53744,0,"chr14","-",24318364,24332484,"ENST00000554577",19,5276,"ENSG00000129467","ADCY4","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0035556(intracellular signal transduction);GO:0016829(lyase activity);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0016849(phosphorus-oxygen lyase activity);GO:0006171(cAMP biosynthetic process);GO:0009190(cyclic nucleotide biosynthetic process);GO:0007165(signal transduction);GO:0007193(adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway);GO:0004016(adenylate cyclase activity);GO:0004383(guanylate cyclase activity);GO:0003091(renal water homeostasis);GO:0006182(cGMP biosynthetic process);GO:0007189(adenylate cyclase-activating G-protein coupled receptor signaling pathway);GO:0007190(activation of adenylate cyclase activity);GO:0034199(activation of protein kinase A activity);GO:0071377(cellular response to glucagon stimulus);GO:0008074(guanylate cyclase complex, soluble);GO:0007188(adenylate cyclase-modulating G-protein coupled receptor signaling pathway);GO:0005622(intracellular);GO:0030425(dendrite)","00230(Purine metabolism);04015(Rap1 signaling pathway);04371(Apelin signaling pathway);04020(Calcium signaling pathway);04072(Phospholipase D signaling pathway);04024(cAMP signaling pathway);04022(cGMP - PKG signaling pathway);04114(Oocyte meiosis);04540(Gap junction);04611(Platelet activation);04062(Chemokine signaling pathway);04911(Insulin secretion);04923(Regulation of lipolysis in adipocyte);04912(GnRH signaling pathway);04913(Ovarian Steroidogenesis);04915(Estrogen signaling pathway);04914(Progesterone-mediated oocyte maturation);04921(Oxytocin signaling pathway);04926(Relaxin signaling pathway);04918(Thyroid hormone synthesis);04916(Melanogenesis);04925(Aldosterone synthesis and secretion);04927(Cortisol synthesis and secretion);04261(Adrenergic signaling in cardiomyocytes);04270(Vascular smooth muscle contraction);04970(Salivary secretion);04971(Gastric acid secretion);04972(Pancreatic secretion);04976(Bile secretion);04724(Glutamatergic synapse);04727(GABAergic synapse);04725(Cholinergic synapse);04723(Retrograde endocannabinoid signaling);04742(Taste transduction);04750(Inflammatory mediator regulation of TRP channels);04211(Longevity regulating pathway - mammal);04213(Longevity regulating pathway - multiple species);04713(Circadian entrainment);05200(Pathways in cancer);05032(Morphine addiction);05414(Dilated cardiomyopathy (DCM));05166(HTLV-I infection);01522(Endocrine resistance)","NA","NA","adenylate cyclase 4 [Source:HGNC Symbol;Acc:HGNC:235]",{"v":0.035087,"d":"0.04"},{"v":0.333566,"d":"0.33"},{"v":0.105187579069809,"d":"0.11"},{"v":-3.24896373885367,"d":"-3.25"},1,1,"down","no"]
[168419,0,"chr6","+",110874784,110895708,"ENST00000368882",5,3059,"MSTRG.13218","AMD1","GO:0016829(lyase activity);GO:0016831(carboxy-lyase activity);GO:0005829(cytosol);GO:0004014(adenosylmethionine decarboxylase activity);GO:0006597(spermine biosynthetic process);GO:0008295(spermidine biosynthetic process);GO:0006596(polyamine biosynthetic process);GO:0006595(polyamine metabolic process);GO:0019810(putrescine binding);GO:0006557(S-adenosylmethioninamine biosynthetic process);GO:0046500(S-adenosylmethionine metabolic process)","00270(Cysteine and methionine metabolism);00330(Arginine and proline metabolism)","K01611","EC:4.1.1.50","adenosylmethionine decarboxylase 1 [Source:HGNC Symbol;Acc:HGNC:457]",0,0,1,0,1,1,"no","no"]
[164105,0,"chr6","+",30651054,30653109,"ENST00000465699",3,692,"MSTRG.12825","C6orf136","GO:0016020(membrane);GO:0016021(integral component of membrane)","NA","NA","NA","chromosome 6 open reading frame 136 [Source:HGNC Symbol;Acc:HGNC:21301]",{"v":0.097291,"d":"0.10"},0,"inf","inf",1,1,"up","no"]
[28218,0,"chr11","+",43335279,43339373,"ENST00000529334",3,346,"MSTRG.2329","API5","GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016607(nuclear speck);GO:0016020(membrane);GO:0005515(protein binding);GO:0005681(spliceosomal complex);GO:0006915(apoptotic process);GO:0043066(negative regulation of apoptotic process);GO:0017134(fibroblast growth factor binding);GO:2000270(negative regulation of fibroblast apoptotic process)","NA","NA","NA","apoptosis inhibitor 5 [Source:HGNC Symbol;Acc:HGNC:594]",{"v":0.702897,"d":"0.70"},{"v":0.454651,"d":"0.45"},{"v":1.54601441545273,"d":"1.55"},{"v":0.628553771400671,"d":"0.63"},1,1,"up","no"]
[104434,0,"chr19","-",50792685,50793584,"ENST00000594114",2,260,"ENSG00000268375","AC010325.2","NA","NA","NA","NA","NA",{"v":0.133886,"d":"0.13"},0,"inf","inf",1,1,"up","no"]
[135927,0,"chr3","-",48603563,48609636,"ENST00000412343",6,778,"MSTRG.10907","UQCRC1","GO:0016020(membrane);GO:0005829(cytosol);GO:0055114(oxidation-reduction process);GO:0005739(mitochondrion);GO:0005743(mitochondrial inner membrane);GO:0046872(metal ion binding);GO:0003824(catalytic activity);GO:1902600(hydrogen ion transmembrane transport);GO:0070469(respiratory chain);GO:0006122(mitochondrial electron transport, ubiquinol to cytochrome c);GO:0005750(mitochondrial respiratory chain complex III);GO:0008270(zinc ion binding);GO:0031625(ubiquitin protein ligase binding);GO:0004222(metalloendopeptidase activity);GO:0016485(protein processing);GO:0009060(aerobic respiration);GO:0008121(ubiquinol-cytochrome-c reductase activity);GO:0006119(oxidative phosphorylation);GO:0005746(mitochondrial respiratory chain);GO:0032403(protein complex binding);GO:0014823(response to activity);GO:0043279(response to alkaloid);GO:0043209(myelin sheath)","00190(Oxidative phosphorylation);04260(Cardiac muscle contraction);05010(Alzheimer's disease);05012(Parkinson's disease);05016(Huntington's disease);04932(Non-alcoholic fatty liver disease (NAFLD))","NA","NA","ubiquinol-cytochrome c reductase core protein I [Source:HGNC Symbol;Acc:HGNC:12585]",{"v":0.225401,"d":"0.23"},{"v":0.3649,"d":"0.36"},{"v":0.617706220882434,"d":"0.62"},{"v":-0.695007234827342,"d":"-0.70"},1,1,"down","no"]
[199188,0,"chrX","+",106639294,106640582,"ENST00000478395",2,425,"ENSG00000147231","CXorf57","GO:0003723(RNA binding);GO:0005515(protein binding)","NA","NA","NA","chromosome X open reading frame 57 [Source:HGNC Symbol;Acc:HGNC:25486]",0,{"v":0.007795,"d":"0.01"},"-inf","-inf",1,1,"down","no"]
[86090,0,"chr17","+",58337336,58351743,"ENST00000582348",3,558,"MSTRG.7060","TSPOAP1-AS1","NA","NA","NA","NA","TSPOAP1 antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:44148]",{"v":0.869233,"d":"0.87"},{"v":1.0289,"d":"1.03"},{"v":0.844817766546798,"d":"0.84"},{"v":-0.243287919945448,"d":"-0.24"},1,1,"down","no"]
[153445,0,"chr5","+",10249929,10265078,"ENST00000503026",11,1933,"MSTRG.11967","CCT5","GO:0005737(cytoplasm);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0005730(nucleolus);GO:0005829(cytosol);GO:0006457(protein folding);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0005874(microtubule);GO:0051082(unfolded protein binding);GO:0005815(microtubule organizing center);GO:0061077(chaperone-mediated protein folding);GO:0070062(extracellular exosome);GO:0009615(response to virus);GO:0050821(protein stabilization);GO:0032212(positive regulation of telomere maintenance via telomerase);GO:0048487(beta-tubulin binding);GO:0005813(centrosome);GO:1904851(positive regulation of establishment of protein localization to telomere);GO:1904874(positive regulation of telomerase RNA localization to Cajal body);GO:0003730(mRNA 3'-UTR binding);GO:0048027(mRNA 5'-UTR binding);GO:0031681(G-protein beta-subunit binding);GO:0044183(protein binding involved in protein folding);GO:0006458('de novo' protein folding);GO:1904871(positive regulation of protein localization to Cajal body);GO:0005832(chaperonin-containing T-complex);GO:0007339(binding of sperm to zona pellucida);GO:1901998(toxin transport);GO:0002199(zona pellucida receptor complex);GO:0043209(myelin sheath);GO:0044297(cell body)","NA","NA","NA","chaperonin containing TCP1 subunit 5 [Source:HGNC Symbol;Acc:HGNC:1618]",0,{"v":0.1102,"d":"0.11"},"-inf","-inf",1,1,"down","no"]
[133266,0,"chr3","+",10026499,10101930,"ENST00000419585",44,5185,"ENSG00000144554","FANCD2","GO:0005634(nucleus);GO:0005730(nucleolus);GO:0005829(cytosol);GO:0006281(DNA repair);GO:0005515(protein binding);GO:0006974(cellular response to DNA damage stimulus);GO:0007049(cell cycle);GO:0016604(nuclear body);GO:0005654(nucleoplasm);GO:0036297(interstrand cross-link repair);GO:0010332(response to gamma radiation);GO:0070182(DNA polymerase binding);GO:0007129(synapsis);GO:0007276(gamete generation);GO:0034599(cellular response to oxidative stress);GO:0045589(regulation of regulatory T cell differentiation);GO:0048854(brain morphogenesis);GO:0050727(regulation of inflammatory response);GO:0051090(regulation of sequence-specific DNA binding transcription factor activity);GO:0097150(neuronal stem cell population maintenance);GO:2000348(regulation of CD40 signaling pathway);GO:0000793(condensed chromosome)","03460(Fanconi anemia pathway)","K10891","NA","Fanconi anemia complementation group D2 [Source:HGNC Symbol;Acc:HGNC:3585]",{"v":0.110872,"d":"0.11"},{"v":0.133828,"d":"0.13"},{"v":0.828466389694234,"d":"0.83"},{"v":-0.271484925388769,"d":"-0.27"},1,1,"down","no"]
[31182,0,"chr11","-",65375195,65383701,"ENST00000526898",10,3088,"ENSG00000162241","SLC25A45","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0055085(transmembrane transport);GO:0005743(mitochondrial inner membrane);GO:0005739(mitochondrion);GO:0006839(mitochondrial transport);GO:0022857(transmembrane transporter activity)","NA","NA","NA","solute carrier family 25 member 45 [Source:HGNC Symbol;Acc:HGNC:27442]",{"v":0.038488,"d":"0.04"},{"v":0.096162,"d":"0.10"},{"v":0.400241259541191,"d":"0.40"},{"v":-1.32105819734074,"d":"-1.32"},1,1,"down","no"]
[122808,0,"chr20","-",31721655,31723989,"ENST00000420488",2,820,"MSTRG.9635","BCL2L1","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005743(mitochondrial inner membrane);GO:0042981(regulation of apoptotic process);GO:0005829(cytosol);GO:0005739(mitochondrion);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0006915(apoptotic process);GO:0030054(cell junction);GO:0045202(synapse);GO:0005741(mitochondrial outer membrane);GO:0031410(cytoplasmic vesicle);GO:0005759(mitochondrial matrix);GO:0005813(centrosome);GO:0005815(microtubule organizing center);GO:0042802(identical protein binding);GO:0006897(endocytosis);GO:0019901(protein kinase binding);GO:0051434(BH3 domain binding);GO:0043066(negative regulation of apoptotic process);GO:0031965(nuclear membrane);GO:0030672(synaptic vesicle membrane);GO:0000910(cytokinesis);GO:2001240(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand);GO:0042803(protein homodimerization activity);GO:1902042(negative regulation of extrinsic apoptotic signaling pathway via death domain receptors);GO:0007093(mitotic cell cycle checkpoint);GO:2001244(positive regulation of intrinsic apoptotic signaling pathway);GO:1902230(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage);GO:0090201(negative regulation of release of cytochrome c from mitochondria);GO:0001836(release of cytochrome c from mitochondria);GO:1900118(negative regulation of execution phase of apoptosis);GO:0034097(response to cytokine);GO:0046902(regulation of mitochondrial membrane permeability);GO:0051881(regulation of mitochondrial membrane potential);GO:0046982(protein heterodimerization activity);GO:0090005(negative regulation of establishment of protein localization to plasma membrane);GO:0008637(apoptotic mitochondrial changes);GO:0097136(Bcl-2 family protein complex);GO:0019050(suppression by virus of host apoptotic process);GO:2001243(negative regulation of intrinsic apoptotic signaling pathway);GO:0001541(ovarian follicle development);GO:0001701(in utero embryonic development);GO:0007281(germ cell development);GO:0007283(spermatogenesis);GO:0008283(cell proliferation);GO:0008284(positive regulation of cell proliferation);GO:0008584(male gonad development);GO:0008630(intrinsic apoptotic signaling pathway in response to DNA damage);GO:0009314(response to radiation);GO:0009566(fertilization);GO:0009615(response to virus);GO:0040007(growth);GO:0043065(positive regulation of apoptotic process);GO:0043524(negative regulation of neuron apoptotic process);GO:0046898(response to cycloheximide);GO:0051402(neuron apoptotic process);GO:0060154(cellular process regulating host cell cycle in response to virus);GO:0070584(mitochondrion morphogenesis);GO:0071230(cellular response to amino acid stimulus);GO:0071312(cellular response to alkaloid);GO:0071480(cellular response to gamma radiation);GO:0071839(apoptotic process in bone marrow);GO:0097192(extrinsic apoptotic signaling pathway in absence of ligand);GO:0097284(hepatocyte apoptotic process);GO:0005622(intracellular);GO:0005783(endoplasmic reticulum);GO:0031966(mitochondrial membrane)","04014(Ras signaling pathway);04630(Jak-STAT signaling pathway);04064(NF-kappa B signaling pathway);04151(PI3K-Akt signaling pathway);04140(Autophagy - animal);04137(Mitophagy - animal);04210(Apoptosis);04215(Apoptosis - multiple species);04621(NOD-like receptor signaling pathway);05200(Pathways in cancer);05202(Transcriptional misregulation in cancers);05212(Pancreatic cancer);05225(Hepatocellular carcinoma);05220(Chronic myeloid leukemia);05222(Small cell lung cancer);05014(Amyotrophic lateral sclerosis (ALS));05166(HTLV-I infection);05145(Toxoplasmosis);01521(EGFR tyrosine kinase inhibitor resistance);01524(Platinum drug resistance)","K04570","NA","BCL2 like 1 [Source:HGNC Symbol;Acc:HGNC:992]",{"v":0.166566,"d":"0.17"},{"v":0.448123,"d":"0.45"},{"v":0.371697056388536,"d":"0.37"},{"v":-1.42780083189748,"d":"-1.43"},1,1,"down","no"]
[171522,0,"chr7","+",5216172,5225854,"ENST00000480238",6,470,"MSTRG.13466","WIPI2","GO:0016020(membrane);GO:0006914(autophagy);GO:0005829(cytosol);GO:0005515(protein binding);GO:0032266(phosphatidylinositol-3-phosphate binding);GO:0080025(phosphatidylinositol-3,5-bisphosphate binding);GO:0000045(autophagosome assembly);GO:0034497(protein localization to pre-autophagosomal structure);GO:0061739(protein lipidation involved in autophagosome assembly);GO:0098792(xenophagy);GO:0000407(pre-autophagosomal structure);GO:0005776(autophagosome);GO:0034045(pre-autophagosomal structure membrane);GO:0000422(mitophagy);GO:0006497(protein lipidation);GO:0044804(nucleophagy);GO:0019898(extrinsic component of membrane);GO:0016236(macroautophagy);GO:0043234(protein complex)","04140(Autophagy - animal);04136(Autophagy - other eukaryotes)","NA","NA","WD repeat domain, phosphoinositide interacting 2 [Source:HGNC Symbol;Acc:HGNC:32225]",{"v":0.082586,"d":"0.08"},0,"inf","inf",1,1,"up","no"]
[54233,0,"chr14","-",34963708,34982532,"ENST00000556705",3,580,"MSTRG.4318","SRP54-AS1","NA","NA","NA","NA","SRP54 antisense RNA 1 (head to head) [Source:HGNC Symbol;Acc:HGNC:50643]",0,{"v":0.254696,"d":"0.25"},"-inf","-inf",1,1,"down","no"]
[181735,0,"chr8","-",18527301,19013686,"ENST00000327040",16,11689,"ENSG00000156011","PSD3","GO:0016020(membrane);GO:0005886(plasma membrane);GO:0043547(positive regulation of GTPase activity);GO:0042995(cell projection);GO:0030054(cell junction);GO:0045202(synapse);GO:0045211(postsynaptic membrane);GO:0005086(ARF guanyl-nucleotide exchange factor activity);GO:0032012(regulation of ARF protein signal transduction);GO:0005085(guanyl-nucleotide exchange factor activity);GO:0032587(ruffle membrane);GO:0014069(postsynaptic density);GO:0005543(phospholipid binding)","04144(Endocytosis)","K12494","NA","pleckstrin and Sec7 domain containing 3 [Source:HGNC Symbol;Acc:HGNC:19093]",{"v":0.003507,"d":"0.00"},0,"inf","inf",1,1,"up","no"]
[12228,0,"chr1","-",156806244,156816848,"ENST00000392306",9,1673,"MSTRG.1089","SH2D2A","GO:0005737(cytoplasm);GO:0009967(positive regulation of signal transduction);GO:0005515(protein binding);GO:0007275(multicellular organism development);GO:0030154(cell differentiation);GO:0005829(cytosol);GO:0017124(SH3 domain binding);GO:0007165(signal transduction);GO:0048010(vascular endothelial growth factor receptor signaling pathway);GO:0001525(angiogenesis);GO:0005070(SH3/SH2 adaptor activity);GO:0008283(cell proliferation)","04370(VEGF signaling pathway)","K08273","NA","SH2 domain containing 2A [Source:HGNC Symbol;Acc:HGNC:10821]",0,{"v":6.7e-05,"d":"0.00"},"-inf","-inf",1,1,"down","no"]
[31171,0,"chr11","+",65343505,65344095,"ENST00000532492",2,438,"MSTRG.2541","DPF2","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0043231(intracellular membrane-bounded organelle);GO:0046872(metal ion binding);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0000790(nuclear chromatin);GO:0005813(centrosome);GO:0005515(protein binding);GO:0006915(apoptotic process);GO:0097190(apoptotic signaling pathway);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding)","NA","NA","NA","double PHD fingers 2 [Source:HGNC Symbol;Acc:HGNC:9964]",{"v":0.332918,"d":"0.33"},{"v":0.290819,"d":"0.29"},{"v":1.14476014290676,"d":"1.14"},{"v":0.19504534776442,"d":"0.20"},1,1,"up","no"]
[38339,0,"chr12","-",7368837,7369493,"ENST00000545597",2,266,"MSTRG.3094","CD163L1","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005886(plasma membrane);GO:0005576(extracellular region);GO:0005044(scavenger receptor activity);GO:0006898(receptor-mediated endocytosis)","NA","NA","NA","CD163 molecule like 1 [Source:HGNC Symbol;Acc:HGNC:30375]",0,{"v":0.092952,"d":"0.09"},"-inf","-inf",1,1,"down","no"]
[105915,0,"chr19","+",55481197,55484373,"ENST00000391718",1,3177,"ENSG00000197483","ZNF628","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0003700(transcription factor activity, sequence-specific DNA binding)","NA","NA","NA","zinc finger protein 628 [Source:HGNC Symbol;Acc:HGNC:28054]",0,{"v":0.682079,"d":"0.68"},"-inf","-inf",1,1,"down","no"]
[174198,0,"chr7","+",55978907,56000178,"ENST00000497279",7,4255,"MSTRG.13648","NIPSNAP2","GO:0005737(cytoplasm);GO:0005739(mitochondrion);GO:0005515(protein binding);GO:0005887(integral component of plasma membrane);GO:0016020(membrane);GO:0006119(oxidative phosphorylation);GO:0006754(ATP biosynthetic process);GO:1901843(positive regulation of high voltage-gated calcium channel activity);GO:2000984(negative regulation of ATP citrate synthase activity)","NA","NA","NA","nipsnap homolog 2 [Source:HGNC Symbol;Acc:HGNC:4179]",{"v":0.173078,"d":"0.17"},{"v":0.071926,"d":"0.07"},{"v":2.40633428801824,"d":"2.41"},{"v":1.26683707566682,"d":"1.27"},1,1,"up","no"]
[124133,0,"chr20","+",45419906,45426018,"ENST00000639872",7,1498,"MSTRG.9792","PIGT","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0006506(GPI anchor biosynthetic process);GO:0005515(protein binding);GO:0016255(attachment of GPI anchor to protein);GO:0042765(GPI-anchor transamidase complex);GO:0030176(integral component of endoplasmic reticulum membrane);GO:0003923(GPI-anchor transamidase activity);GO:0030182(neuron differentiation);GO:0051402(neuron apoptotic process);GO:0005737(cytoplasm);GO:0031410(cytoplasmic vesicle)","00563(Glycosylphosphatidylinositol(GPI)-anchor biosynthesis)","NA","NA","phosphatidylinositol glycan anchor biosynthesis class T [Source:HGNC Symbol;Acc:HGNC:14938]",{"v":0.412901,"d":"0.41"},{"v":0.006511,"d":"0.01"},{"v":63.4159115343265,"d":"63.42"},{"v":5.98677296382572,"d":"5.99"},1,1,"up","no"]
[27421,0,"chr11","+",22342977,22360965,"ENST00000534115",3,573,"ENSG00000091664","SLC17A6","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0055085(transmembrane transport);GO:0015293(symporter activity);GO:0006811(ion transport);GO:0006814(sodium ion transport);GO:0030054(cell junction);GO:0045202(synapse);GO:0031410(cytoplasmic vesicle);GO:0043005(neuron projection);GO:0030672(synaptic vesicle membrane);GO:0006836(neurotransmitter transport);GO:0005313(L-glutamate transmembrane transporter activity);GO:0089711(L-glutamate transmembrane transport);GO:0098700(neurotransmitter loading into synaptic vesicle)","04724(Glutamatergic synapse);04723(Retrograde endocannabinoid signaling);04721(Synaptic vesicle cycle);05033(Nicotine addiction)","NA","NA","solute carrier family 17 member 6 [Source:HGNC Symbol;Acc:HGNC:16703]",0,{"v":0.036494,"d":"0.04"},"-inf","-inf",1,1,"down","no"]
[141539,0,"chr3","-",149034989,149040259,"ENST00000472830",4,533,"ENSG00000071794","HLTF","GO:0003676(nucleic acid binding);GO:0008270(zinc ion binding);GO:0005524(ATP binding);GO:0005634(nucleus);GO:0005654(nucleoplasm);GO:0016818(hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0061630(ubiquitin protein ligase activity);GO:0016887(ATPase activity);GO:0000209(protein polyubiquitination);GO:0006301(postreplication repair);GO:0003723(RNA binding);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0016740(transferase activity);GO:0006366(transcription from RNA polymerase II promoter);GO:0016787(hydrolase activity);GO:0006351(transcription, DNA-templated);GO:0016569(covalent chromatin modification);GO:0016567(protein ubiquitination);GO:0004386(helicase activity);GO:0003677(DNA binding);GO:0005515(protein binding);GO:0003824(catalytic activity);GO:0008152(metabolic process);GO:0005730(nucleolus);GO:0006355(regulation of transcription, DNA-templated);GO:0031625(ubiquitin protein ligase binding);GO:0000978(RNA polymerase II core promoter proximal region sequence-specific DNA binding);GO:0001077(transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0045944(positive regulation of transcription from RNA polymerase II promoter)","NA","NA","NA","helicase like transcription factor [Source:HGNC Symbol;Acc:HGNC:11099]",0,0,1,0,1,1,"no","no"]
[107432,0,"chr2","+",11783869,11784849,"ENST00000475286",2,192,"MSTRG.8521","LPIN1","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0016787(hydrolase activity);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0006629(lipid metabolic process);GO:0005829(cytosol);GO:0008195(phosphatidate phosphatase activity);GO:0016311(dephosphorylation);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0006631(fatty acid metabolic process);GO:0019432(triglyceride biosynthetic process);GO:0009062(fatty acid catabolic process);GO:0003674(molecular_function);GO:0005654(nucleoplasm);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0031965(nuclear membrane);GO:0007077(mitotic nuclear envelope disassembly);GO:0003713(transcription coactivator activity);GO:0005635(nuclear envelope);GO:0006656(phosphatidylcholine biosynthetic process);GO:0006646(phosphatidylethanolamine biosynthetic process);GO:0005741(mitochondrial outer membrane);GO:0006642(triglyceride mobilization);GO:0031100(animal organ regeneration);GO:0032869(cellular response to insulin stimulus)","00561(Glycerolipid metabolism);00564(Glycerophospholipid metabolism);04150(mTOR signaling pathway)","NA","NA","lipin 1 [Source:HGNC Symbol;Acc:HGNC:13345]",{"v":0.151364,"d":"0.15"},{"v":0.190207,"d":"0.19"},{"v":0.79578564406147,"d":"0.80"},{"v":-0.329548221776972,"d":"-0.33"},1,1,"down","no"]
[14223,0,"chr1","-",183460874,183471746,"ENST00000421703",5,2220,"MSTRG.1251","SMG7-AS1","NA","NA","NA","NA","SMG7 antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:24518]",0,{"v":0.006302,"d":"0.01"},"-inf","-inf",1,1,"down","no"]
[436,0,"chr1","+",1399562,1400544,"ENST00000570344",2,515,"MSTRG.58","AL391244.1","NA","NA","NA","NA","NA",0,{"v":0.137504,"d":"0.14"},"-inf","-inf",1,1,"down","no"]
[28672,0,"chr11","-",47167909,47176846,"ENST00000532478",9,940,"MSTRG.2366","ARFGAP2","GO:0006810(transport);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0015031(protein transport);GO:0005794(Golgi apparatus);GO:0046872(metal ion binding);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0043547(positive regulation of GTPase activity);GO:0005096(GTPase activator activity);GO:0000139(Golgi membrane);GO:0016192(vesicle-mediated transport);GO:0006890(retrograde vesicle-mediated transport, Golgi to ER);GO:0006888(ER to Golgi vesicle-mediated transport)","04144(Endocytosis)","NA","NA","ADP ribosylation factor GTPase activating protein 2 [Source:HGNC Symbol;Acc:HGNC:13504]",0,0,1,0,1,1,"no","no"]
[2537,0,"chr1","-",22023997,22025483,"ENST00000635097",3,1023,"MSTRG.223","LINC01635","NA","NA","NA","NA","long intergenic non-protein coding RNA 1635 [Source:HGNC Symbol;Acc:HGNC:52422]",{"v":0.100493,"d":"0.10"},0,"inf","inf",1,1,"up","no"]
[8449,0,"chr1","+",100538137,100542018,"ENST00000315033",2,3491,"ENSG00000181656","GPR88","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0004930(G-protein coupled receptor activity);GO:0007186(G-protein coupled receptor signaling pathway);GO:0005886(plasma membrane);GO:0004871(signal transducer activity);GO:0007165(signal transduction);GO:0003774(motor activity);GO:0005575(cellular_component);GO:0007268(chemical synaptic transmission);GO:0007631(feeding behavior);GO:0007218(neuropeptide signaling pathway);GO:0007626(locomotory behavior);GO:0019228(neuronal action potential);GO:0050885(neuromuscular process controlling balance);GO:0061743(motor learning)","NA","NA","NA","G protein-coupled receptor 88 [Source:HGNC Symbol;Acc:HGNC:4539]",{"v":0.052516,"d":"0.05"},{"v":0.084651,"d":"0.08"},{"v":0.62038251172461,"d":"0.62"},{"v":-0.688770076797996,"d":"-0.69"},1,1,"down","no"]
[135019,0,"chr3","-",40391850,40453180,"ENST00000452768",5,724,"ENSG00000223797","ENTPD3-AS1","NA","NA","NA","NA","ENTPD3 antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:26710]",{"v":0.027542,"d":"0.03"},0,"inf","inf",1,1,"up","no"]
[190956,0,"chr9","+",69820960,69858158,"ENST00000480564",4,550,"ENSG00000204711","C9orf135","GO:0016020(membrane);GO:0016021(integral component of membrane)","NA","NA","NA","chromosome 9 open reading frame 135 [Source:HGNC Symbol;Acc:HGNC:31422]",0,{"v":0.079358,"d":"0.08"},"-inf","-inf",1,1,"down","no"]
[152988,0,"chr5","+",218311,224843,"ENST00000502379",3,679,"MSTRG.11946","SDHA","GO:0016020(membrane);GO:0005730(nucleolus);GO:0016491(oxidoreductase activity);GO:0050660(flavin adenine dinucleotide binding);GO:0055114(oxidation-reduction process);GO:0008177(succinate dehydrogenase (ubiquinone) activity);GO:0016627(oxidoreductase activity, acting on the CH-CH group of donors);GO:0006099(tricarboxylic acid cycle);GO:0006105(succinate metabolic process);GO:0022900(electron transport chain);GO:0022904(respiratory electron transport chain);GO:0005739(mitochondrion);GO:0005743(mitochondrial inner membrane);GO:0043209(myelin sheath);GO:0005515(protein binding);GO:0007399(nervous system development);GO:0006121(mitochondrial electron transport, succinate to ubiquinone);GO:0000104(succinate dehydrogenase activity);GO:0005749(mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone));GO:0009055(electron carrier activity);GO:0009061(anaerobic respiration)","00020(Citrate cycle (TCA cycle));00190(Oxidative phosphorylation);05010(Alzheimer's disease);05012(Parkinson's disease);05016(Huntington's disease);04932(Non-alcoholic fatty liver disease (NAFLD))","NA","NA","succinate dehydrogenase complex flavoprotein subunit A [Source:HGNC Symbol;Acc:HGNC:10680]",{"v":0.480001,"d":"0.48"},0,"inf","inf",1,1,"up","no"]
[119144,0,"chr2","-",218638145,218659502,"ENST00000433921",11,5800,"ENSG00000115568","ZNF142","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0003677(DNA binding);GO:0003674(molecular_function);GO:0008150(biological_process);GO:0005575(cellular_component)","NA","NA","NA","zinc finger protein 142 [Source:HGNC Symbol;Acc:HGNC:12927]",0,0,1,0,1,1,"no","no"]
[38766,0,"chr12","-",10118068,10130185,"ENST00000396484",4,1000,"MSTRG.3163","CLEC7A","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0043231(intracellular membrane-bounded organelle);GO:0046872(metal ion binding);GO:0005654(nucleoplasm);GO:0030246(carbohydrate binding);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0002376(immune system process);GO:0045087(innate immune response);GO:0006954(inflammatory response);GO:0002221(pattern recognition receptor signaling pathway);GO:0002223(stimulatory C-type lectin receptor signaling pathway);GO:0042110(T cell activation);GO:0008329(signaling pattern recognition receptor activity);GO:0006910(phagocytosis, recognition);GO:0008037(cell recognition);GO:0042832(defense response to protozoan);GO:0042287(MHC protein binding);GO:0009756(carbohydrate mediated signaling)","04145(Phagosome);05152(Tuberculosis)","K10074","NA","C-type lectin domain containing 7A [Source:HGNC Symbol;Acc:HGNC:14558]",{"v":0.774823,"d":"0.77"},{"v":0.267507,"d":"0.27"},{"v":2.89645878425611,"d":"2.90"},{"v":1.534290136036,"d":"1.53"},1,1,"up","no"]
[91536,0,"chr18","-",31129236,31162856,"ENST00000257198",16,4225,"MSTRG.7457","DSC1","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0046872(metal ion binding);GO:0005509(calcium ion binding);GO:0007155(cell adhesion);GO:0007156(homophilic cell adhesion via plasma membrane adhesion molecules);GO:0005886(plasma membrane);GO:0030054(cell junction);GO:0070062(extracellular exosome);GO:0031424(keratinization);GO:0043312(neutrophil degranulation);GO:0101003(ficolin-1-rich granule membrane);GO:0070268(cornification);GO:0001533(cornified envelope);GO:0030057(desmosome);GO:0005921(gap junction)","NA","NA","NA","desmocollin 1 [Source:HGNC Symbol;Acc:HGNC:3035]",{"v":0.09887,"d":"0.10"},0,"inf","inf",1,1,"up","no"]
[169233,0,"chr6","+",132160765,132164491,"ENST00000447481",2,745,"ENSG00000228495","LINC01013","NA","NA","NA","NA","long intergenic non-protein coding RNA 1013 [Source:HGNC Symbol;Acc:HGNC:48987]",0,0,1,0,1,1,"no","no"]
[59055,0,"chr14","+",103466363,103467685,"ENST00000558611",2,687,"MSTRG.4702","MARK3","GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0000226(microtubule cytoskeleton organization);GO:0030010(establishment of cell polarity);GO:0016020(membrane);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0000165(MAPK cascade);GO:0035331(negative regulation of hippo signaling)","NA","NA","NA","microtubule affinity regulating kinase 3 [Source:HGNC Symbol;Acc:HGNC:6897]",{"v":0.792576,"d":"0.79"},{"v":0.720411,"d":"0.72"},{"v":1.10017198515847,"d":"1.10"},{"v":0.137729071695653,"d":"0.14"},1,1,"up","no"]
[138985,0,"chr3","+",111071743,111135954,"ENST00000485303",6,3664,"ENSG00000177707","NECTIN3","GO:0007155(cell adhesion);GO:0046982(protein heterodimerization activity);GO:0005911(cell-cell junction);GO:0042803(protein homodimerization activity);GO:0007286(spermatid development);GO:0050839(cell adhesion molecule binding);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0030054(cell junction);GO:0045202(synapse);GO:0045211(postsynaptic membrane);GO:0005887(integral component of plasma membrane);GO:0004872(receptor activity);GO:0005102(receptor binding);GO:0007156(homophilic cell adhesion via plasma membrane adhesion molecules);GO:0007157(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules);GO:0005913(cell-cell adherens junction);GO:0034332(adherens junction organization);GO:0008037(cell recognition);GO:0002089(lens morphogenesis in camera-type eye);GO:0009566(fertilization);GO:0016337(single organismal cell-cell adhesion);GO:0060042(retina morphogenesis in camera-type eye);GO:1902414(protein localization to cell junction);GO:0043296(apical junction complex);GO:0044291(cell-cell contact zone)","04514(Cell adhesion molecules (CAMs));04520(Adherens junction)","K06592","NA","nectin cell adhesion molecule 3 [Source:HGNC Symbol;Acc:HGNC:17664]",{"v":0.057605,"d":"0.06"},{"v":0.048812,"d":"0.05"},{"v":1.18014012947636,"d":"1.18"},{"v":0.238958174924149,"d":"0.24"},1,1,"up","no"]
[38522,0,"chr12","-",8534509,8540873,"ENST00000545274",5,730,"MSTRG.3113","CLEC4E","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0030246(carbohydrate binding);GO:0002376(immune system process);GO:0005886(plasma membrane);GO:0002223(stimulatory C-type lectin receptor signaling pathway);GO:0004872(receptor activity);GO:0002292(T cell differentiation involved in immune response);GO:0006955(immune response);GO:0038094(Fc-gamma receptor signaling pathway);GO:0042742(defense response to bacterium);GO:0045087(innate immune response);GO:0050715(positive regulation of cytokine secretion)","05152(Tuberculosis)","K10059","NA","C-type lectin domain family 4 member E [Source:HGNC Symbol;Acc:HGNC:14555]",{"v":0.2295,"d":"0.23"},{"v":0.2564,"d":"0.26"},{"v":0.895085803432137,"d":"0.90"},{"v":-0.159902108317571,"d":"-0.16"},1,1,"down","no"]
[193817,0,"chr9","+",128378067,128389869,"ENST00000483206",3,731,"MSTRG.14994","URM1","GO:0005737(cytoplasm);GO:0008033(tRNA processing);GO:0005829(cytosol);GO:0002098(tRNA wobble uridine modification);GO:0032447(protein urmylation);GO:0034227(tRNA thio-modification);GO:0016783(sulfurtransferase activity);GO:0005515(protein binding);GO:0070062(extracellular exosome);GO:0006400(tRNA modification)","04122(Sulfur relay system)","NA","NA","ubiquitin related modifier 1 [Source:HGNC Symbol;Acc:HGNC:28378]",{"v":0.691903,"d":"0.69"},{"v":0.391488,"d":"0.39"},{"v":1.76736707127677,"d":"1.77"},{"v":0.821601709902221,"d":"0.82"},1,1,"up","no"]
[119412,0,"chr2","+",219245896,219247534,"ENST00000486813",3,444,"MSTRG.9450","STK16","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0005829(cytosol);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0006366(transcription from RNA polymerase II promoter);GO:0018108(peptidyl-tyrosine phosphorylation);GO:0005515(protein binding);GO:0004715(non-membrane spanning protein tyrosine kinase activity);GO:0048471(perinuclear region of cytoplasm);GO:0001077(transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0046777(protein autophosphorylation);GO:0071560(cellular response to transforming growth factor beta stimulus);GO:0005798(Golgi-associated vesicle)","NA","NA","NA","serine/threonine kinase 16 [Source:HGNC Symbol;Acc:HGNC:11394]",0,0,1,0,1,1,"no","no"]
[26145,0,"chr11","-",6617370,6619396,"ENST00000530040",4,551,"MSTRG.2214","TPP1","GO:0046872(metal ion binding);GO:0016787(hydrolase activity);GO:0005515(protein binding);GO:0008233(peptidase activity);GO:0006508(proteolysis);GO:0004252(serine-type endopeptidase activity);GO:0042470(melanosome);GO:0008236(serine-type peptidase activity);GO:0007399(nervous system development);GO:0005764(lysosome);GO:0045453(bone resorption);GO:0070062(extracellular exosome);GO:0030855(epithelial cell differentiation);GO:0043202(lysosomal lumen);GO:0006629(lipid metabolic process);GO:0007417(central nervous system development);GO:0036498(IRE1-mediated unfolded protein response);GO:0004175(endopeptidase activity);GO:0008240(tripeptidyl-peptidase activity);GO:0042277(peptide binding);GO:0007040(lysosome organization);GO:0030163(protein catabolic process);GO:0043171(peptide catabolic process);GO:0050885(neuromuscular process controlling balance);GO:0005739(mitochondrion)","04142(Lysosome)","NA","NA","tripeptidyl peptidase 1 [Source:HGNC Symbol;Acc:HGNC:2073]",{"v":1.14073,"d":"1.14"},{"v":0.059439,"d":"0.06"},{"v":19.1916082033682,"d":"19.19"},{"v":4.26240370531645,"d":"4.26"},1,1,"up","no"]
[148753,0,"chr4","-",82897856,82900569,"ENST00000505028",3,552,"MSTRG.11700","THAP9-AS1","NA","NA","NA","NA","THAP9 antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:44172]",{"v":0.361026,"d":"0.36"},0,"inf","inf",1,1,"up","no"]
[90031,0,"chr17","+",82939401,82942702,"ENST00000572794",2,1380,"ENSG00000141556","TBCD","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005886(plasma membrane);GO:0043547(positive regulation of GTPase activity);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0005096(GTPase activator activity);GO:0030054(cell junction);GO:0005813(centrosome);GO:0005815(microtubule organizing center);GO:0005923(bicellular tight junction);GO:0005912(adherens junction);GO:0006457(protein folding);GO:0048487(beta-tubulin binding);GO:0007021(tubulin complex assembly);GO:0007023(post-chaperonin tubulin folding pathway);GO:0016328(lateral plasma membrane);GO:0000278(mitotic cell cycle);GO:0070830(bicellular tight junction assembly);GO:0034333(adherens junction assembly);GO:0051087(chaperone binding);GO:0031115(negative regulation of microtubule polymerization);GO:0010812(negative regulation of cell-substrate adhesion);GO:0005874(microtubule);GO:0048667(cell morphogenesis involved in neuron differentiation)","NA","NA","NA","tubulin folding cofactor D [Source:HGNC Symbol;Acc:HGNC:11581]",{"v":0.041559,"d":"0.04"},{"v":0.092034,"d":"0.09"},{"v":0.451561379490188,"d":"0.45"},{"v":-1.14700599230298,"d":"-1.15"},1,1,"down","no"]
[105837,0,"chr19","+",55284166,55312533,"ENST00000309383",19,3079,"ENSG00000160469","BRSK1","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0005654(nucleoplasm);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0030054(cell junction);GO:0005856(cytoskeleton);GO:0006974(cellular response to DNA damage stimulus);GO:0007049(cell cycle);GO:0000287(magnesium ion binding);GO:0045202(synapse);GO:0007399(nervous system development);GO:0005813(centrosome);GO:0005815(microtubule organizing center);GO:0035556(intracellular signal transduction);GO:0007409(axonogenesis);GO:0009411(response to UV);GO:0030182(neuron differentiation);GO:0008021(synaptic vesicle);GO:0031572(G2 DNA damage checkpoint);GO:0007269(neurotransmitter secretion);GO:0030010(establishment of cell polarity);GO:0051298(centrosome duplication);GO:0043015(gamma-tubulin binding);GO:0050321(tau-protein kinase activity);GO:0019901(protein kinase binding);GO:0048812(neuron projection morphogenesis)","NA","NA","NA","BR serine/threonine kinase 1 [Source:HGNC Symbol;Acc:HGNC:18994]",{"v":0.234481,"d":"0.23"},{"v":0.124157,"d":"0.12"},{"v":1.88858461464114,"d":"1.89"},{"v":0.917305422585862,"d":"0.92"},1,1,"up","no"]
[135324,0,"chr3","+",43690113,43702584,"ENST00000456453",4,876,"MSTRG.10859","ABHD5","GO:0006508(proteolysis);GO:0008233(peptidase activity);GO:0005737(cytoplasm);GO:0016740(transferase activity);GO:0016787(hydrolase activity);GO:0016746(transferase activity, transferring acyl groups);GO:0006629(lipid metabolic process);GO:0005829(cytosol);GO:0006631(fatty acid metabolic process);GO:0008654(phospholipid biosynthetic process);GO:0030154(cell differentiation);GO:0003841(1-acylglycerol-3-phosphate O-acyltransferase activity);GO:0010891(negative regulation of sequestering of triglyceride);GO:0010898(positive regulation of triglyceride catabolic process);GO:0050996(positive regulation of lipid catabolic process);GO:0051006(positive regulation of lipoprotein lipase activity);GO:0005811(lipid particle);GO:0006654(phosphatidic acid biosynthetic process);GO:0042171(lysophosphatidic acid acyltransferase activity)","04923(Regulation of lipolysis in adipocyte)","NA","NA","abhydrolase domain containing 5 [Source:HGNC Symbol;Acc:HGNC:21396]",{"v":0.064742,"d":"0.06"},0,"inf","inf",1,1,"up","no"]
[174093,0,"chr7","+",53862233,53863339,"ENST00000456660",1,1107,"ENSG00000235454","HAUS6P3","NA","NA","NA","NA","HAUS augmin like complex subunit 6 pseudogene 3 [Source:HGNC Symbol;Acc:HGNC:50772]",{"v":0.023217,"d":"0.02"},0,"inf","inf",1,1,"up","no"]
[108557,0,"chr2","+",32165841,32224112,"ENST00000435660",13,4776,"ENSG00000152683","SLC30A6","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0055085(transmembrane transport);GO:0098655(cation transmembrane transport);GO:0006812(cation transport);GO:0008324(cation transmembrane transporter activity);GO:0006810(transport);GO:0005794(Golgi apparatus);GO:0006811(ion transport);GO:0071577(zinc II ion transmembrane transport);GO:0005385(zinc ion transmembrane transporter activity);GO:0000139(Golgi membrane);GO:0006829(zinc II ion transport);GO:0010043(response to zinc ion);GO:0061088(regulation of sequestering of zinc ion)","NA","NA","NA","solute carrier family 30 member 6 [Source:HGNC Symbol;Acc:HGNC:19305]",0,0,1,0,1,1,"no","no"]
[111213,0,"chr2","-",74377432,74391843,"ENST00000417090",5,556,"MSTRG.8832","DCTN1","GO:0006810(transport);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005829(cytosol);GO:0051301(cell division);GO:0005813(centrosome);GO:0015629(actin cytoskeleton);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0007049(cell cycle);GO:0007399(nervous system development);GO:0005874(microtubule);GO:0003774(motor activity);GO:0008017(microtubule binding);GO:0000922(spindle pole);GO:0005815(microtubule organizing center);GO:0005819(spindle);GO:0000776(kinetochore);GO:0005869(dynactin complex);GO:0030286(dynein complex);GO:0005814(centriole);GO:0005938(cell cortex);GO:0042147(retrograde transport, endosome to Golgi);GO:0000086(G2/M transition of mitotic cell cycle);GO:0010389(regulation of G2/M transition of mitotic cell cycle);GO:0097711(ciliary basal body docking);GO:0070840(dynein complex binding);GO:0010970(transport along microtubule);GO:0019886(antigen processing and presentation of exogenous peptide antigen via MHC class II);GO:0006888(ER to Golgi vesicle-mediated transport);GO:0015631(tubulin binding);GO:0005635(nuclear envelope);GO:0036498(IRE1-mediated unfolded protein response);GO:0000132(establishment of mitotic spindle orientation);GO:0000278(mitotic cell cycle);GO:0099738(cell cortex region);GO:0030904(retromer complex);GO:0031116(positive regulation of microtubule polymerization);GO:0090063(positive regulation of microtubule nucleation);GO:0035371(microtubule plus-end);GO:0060236(regulation of mitotic spindle organization);GO:0051081(nuclear envelope disassembly);GO:0010457(centriole-centriole cohesion);GO:0032402(melanosome transport);GO:0034454(microtubule anchoring at centrosome);GO:1905515(non-motile cilium assembly);GO:0031252(cell leading edge);GO:0043234(protein complex)","04962(Vasopressin-regulated water reabsorption);05016(Huntington's disease)","NA","NA","dynactin subunit 1 [Source:HGNC Symbol;Acc:HGNC:2711]",0,0,1,0,1,1,"no","no"]
[134745,0,"chr3","-",37808496,37861732,"ENST00000630010",4,575,"MSTRG.10807","ITGA9-AS1","NA","NA","NA","NA","ITGA9 antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:49668]",0,{"v":0.3568,"d":"0.36"},"-inf","-inf",1,1,"down","no"]
[101969,0,"chr19","+",41895379,41930150,"ENST00000599589",21,2636,"MSTRG.8188","ARHGEF1","GO:0003723(RNA binding);GO:0005737(cytoplasm);GO:0016020(membrane);GO:0005829(cytosol);GO:0005886(plasma membrane);GO:0005089(Rho guanyl-nucleotide exchange factor activity);GO:0035023(regulation of Rho protein signal transduction);GO:0043547(positive regulation of GTPase activity);GO:0005515(protein binding);GO:0005096(GTPase activator activity);GO:0005085(guanyl-nucleotide exchange factor activity);GO:0051056(regulation of small GTPase mediated signal transduction);GO:0007266(Rho protein signal transduction);GO:0008283(cell proliferation);GO:0043065(positive regulation of apoptotic process);GO:0050771(negative regulation of axonogenesis)","04810(Regulation of actin cytoskeleton);04611(Platelet activation);04270(Vascular smooth muscle contraction);05200(Pathways in cancer);05205(Proteoglycans in cancer)","NA","NA","Rho guanine nucleotide exchange factor 1 [Source:HGNC Symbol;Acc:HGNC:681]",{"v":0.077798,"d":"0.08"},{"v":0.048631,"d":"0.05"},{"v":1.59976146902182,"d":"1.60"},{"v":0.677856809416729,"d":"0.68"},1,1,"up","no"]
[67302,0,"chr16","-",188969,229463,"ENST00000337351",9,2097,"ENSG00000007392","LUC7L","GO:0003729(mRNA binding);GO:0005515(protein binding);GO:0042802(identical protein binding);GO:0005685(U1 snRNP);GO:0006376(mRNA splice site selection);GO:0071004(U2-type prespliceosome);GO:0050733(RS domain binding);GO:0045843(negative regulation of striated muscle tissue development);GO:0005634(nucleus)","NA","NA","NA","LUC7 like [Source:HGNC Symbol;Acc:HGNC:6723]",{"v":0.978332,"d":"0.98"},{"v":0.027102,"d":"0.03"},{"v":36.0981477381743,"d":"36.10"},{"v":5.17385290658407,"d":"5.17"},1,1,"up","no"]
[39764,0,"chr12","+",25803298,25804526,"ENST00000543961",1,1229,"ENSG00000255725","TDGP1","NA","NA","NA","NA","thymine-DNA glycosylase pseudogene 1 [Source:HGNC Symbol;Acc:HGNC:49891]",{"v":0.644721,"d":"0.64"},{"v":0.117679,"d":"0.12"},{"v":5.47864104895521,"d":"5.48"},{"v":2.45381808386722,"d":"2.45"},1,1,"up","no"]
[185889,0,"chr8","-",98401403,98526926,"ENST00000517832",4,594,"ENSG00000104375","STK3","GO:0090090(negative regulation of canonical Wnt signaling pathway);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0004672(protein kinase activity);GO:0004674(protein serine/threonine kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0007165(signal transduction);GO:0005515(protein binding);GO:0006915(apoptotic process);GO:0000287(magnesium ion binding);GO:0005829(cytosol);GO:0043065(positive regulation of apoptotic process);GO:0043234(protein complex);GO:0071902(positive regulation of protein serine/threonine kinase activity);GO:0042981(regulation of apoptotic process);GO:0007346(regulation of mitotic cell cycle);GO:0035556(intracellular signal transduction);GO:0035329(hippo signaling);GO:0046983(protein dimerization activity);GO:0031098(stress-activated protein kinase signaling cascade);GO:0023014(signal transduction by protein phosphorylation);GO:0043539(protein serine/threonine kinase activator activity);GO:0032092(positive regulation of protein binding);GO:0050821(protein stabilization);GO:0051091(positive regulation of sequence-specific DNA binding transcription factor activity);GO:0001841(neural tube formation);GO:0003157(endocardium development);GO:0007417(central nervous system development);GO:0008285(negative regulation of cell proliferation);GO:0045600(positive regulation of fat cell differentiation);GO:0046330(positive regulation of JNK cascade);GO:0046621(negative regulation of organ growth);GO:0051897(positive regulation of protein kinase B signaling);GO:0060215(primitive hemopoiesis);GO:0060706(cell differentiation involved in embryonic placenta development);GO:0060800(regulation of cell differentiation involved in embryonic placenta development);GO:0097284(hepatocyte apoptotic process);GO:1902043(positive regulation of extrinsic apoptotic signaling pathway via death domain receptors)","04010(MAPK signaling pathway);04390(Hippo signaling pathway);04392(Hippo signaling pathway - multiple species)","NA","NA","serine/threonine kinase 3 [Source:HGNC Symbol;Acc:HGNC:11406]",0,0,1,0,1,1,"no","no"]
[21019,0,"chr10","+",70672803,70762441,"ENST00000373208",22,5269,"ENSG00000138316","ADAMTS14","GO:0008270(zinc ion binding);GO:0046872(metal ion binding);GO:0016787(hydrolase activity);GO:0008233(peptidase activity);GO:0006508(proteolysis);GO:0005576(extracellular region);GO:0005578(proteinaceous extracellular matrix);GO:0004222(metalloendopeptidase activity);GO:0008237(metallopeptidase activity);GO:0030574(collagen catabolic process);GO:0030199(collagen fibril organization)","NA","NA","NA","ADAM metallopeptidase with thrombospondin type 1 motif 14 [Source:HGNC Symbol;Acc:HGNC:14899]",{"v":0.020509,"d":"0.02"},{"v":0.033012,"d":"0.03"},{"v":0.621258936144432,"d":"0.62"},{"v":-0.686733396440146,"d":"-0.69"},1,1,"down","no"]
[88878,0,"chr17","-",78812860,78828964,"ENST00000586066",10,960,"MSTRG.7296","USP36","GO:0003723(RNA binding);GO:0005634(nucleus);GO:0016607(nuclear speck);GO:0005730(nucleolus);GO:0016579(protein deubiquitination);GO:0016787(hydrolase activity);GO:0008233(peptidase activity);GO:0008234(cysteine-type peptidase activity);GO:0006508(proteolysis);GO:0006511(ubiquitin-dependent protein catabolic process);GO:0036459(thiol-dependent ubiquitinyl hydrolase activity);GO:1903146(regulation of mitophagy);GO:0004843(thiol-dependent ubiquitin-specific protease activity);GO:1903955(positive regulation of protein targeting to mitochondrion)","NA","NA","NA","ubiquitin specific peptidase 36 [Source:HGNC Symbol;Acc:HGNC:20062]",0,{"v":9.5E-4,"d":"0.00"},"-inf","-inf",1,1,"down","no"]
[85296,0,"chr17","-",49621946,49646622,"ENST00000510476",3,773,"MSTRG.7004","SPOP","GO:0005634(nucleus);GO:0016607(nuclear speck);GO:0016567(protein ubiquitination);GO:0005515(protein binding);GO:0005737(cytoplasm);GO:0005654(nucleoplasm);GO:0030162(regulation of proteolysis);GO:0042787(protein ubiquitination involved in ubiquitin-dependent protein catabolic process);GO:0019005(SCF ubiquitin ligase complex);GO:0031625(ubiquitin protein ligase binding);GO:0043161(proteasome-mediated ubiquitin-dependent protein catabolic process);GO:0031463(Cul3-RING ubiquitin ligase complex);GO:0001085(RNA polymerase II transcription factor binding);GO:0000122(negative regulation of transcription from RNA polymerase II promoter);GO:0042593(glucose homeostasis);GO:0043433(negative regulation of sequence-specific DNA binding transcription factor activity);GO:1902237(positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway);GO:2000676(positive regulation of type B pancreatic cell apoptotic process)","04340(Hedgehog signaling pathway)","NA","NA","speckle type BTB/POZ protein [Source:HGNC Symbol;Acc:HGNC:11254]",0,0,1,0,1,1,"no","no"]
[64868,0,"chr15","+",75336060,75339400,"ENST00000567023",4,926,"ENSG00000140365","COMMD4","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0005515(protein binding)","NA","NA","NA","COMM domain containing 4 [Source:HGNC Symbol;Acc:HGNC:26027]",{"v":0.190376,"d":"0.19"},0,"inf","inf",1,1,"up","no"]
[200945,0,"chrX","-",153703001,153724044,"ENST00000423827",6,669,"MSTRG.15486","BCAP31","GO:0005739(mitochondrion);GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0006886(intracellular protein transport);GO:0015031(protein transport);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005515(protein binding);GO:0006915(apoptotic process);GO:0016192(vesicle-mediated transport);GO:0005887(integral component of plasma membrane);GO:0005829(cytosol);GO:0006888(ER to Golgi vesicle-mediated transport);GO:0097194(execution phase of apoptosis);GO:2001244(positive regulation of intrinsic apoptotic signaling pathway);GO:0007204(positive regulation of cytosolic calcium ion concentration);GO:0005811(lipid particle);GO:0043280(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process);GO:0033116(endoplasmic reticulum-Golgi intermediate compartment membrane);GO:0002474(antigen processing and presentation of peptide antigen via MHC class I);GO:0071556(integral component of lumenal side of endoplasmic reticulum membrane);GO:1903071(positive regulation of ER-associated ubiquitin-dependent protein catabolic process);GO:0035584(calcium-mediated signaling using intracellular calcium source);GO:0032471(negative regulation of endoplasmic reticulum calcium ion concentration);GO:0051561(positive regulation of mitochondrial calcium ion concentration);GO:0005784(Sec61 translocon complex);GO:0070973(protein localization to endoplasmic reticulum exit site);GO:1904154(positive regulation of retrograde protein transport, ER to cytosol);GO:0097038(perinuclear endoplasmic reticulum);GO:0032403(protein complex binding);GO:0042288(MHC class I protein binding);GO:0007283(spermatogenesis);GO:0000139(Golgi membrane);GO:0030136(clathrin-coated vesicle);GO:0032580(Golgi cisterna membrane)","04141(Protein processing in endoplasmic reticulum);05165(Human papillomavirus infection)","NA","NA","B-cell receptor associated protein 31 [Source:HGNC Symbol;Acc:HGNC:16695]",0,0,1,0,1,1,"no","no"]
[178587,0,"chr7","+",128866308,128872044,"ENST00000609480",2,3902,"MSTRG.13958","AC025594.2","NA","NA","NA","NA","NA",{"v":0.181088,"d":"0.18"},{"v":0.115637,"d":"0.12"},{"v":1.56600396067003,"d":"1.57"},{"v":0.647087861435966,"d":"0.65"},1,1,"up","no"]
[123257,0,"chr20","+",35542443,35556262,"ENST00000496172",8,781,"MSTRG.9699","ERGIC3","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005794(Golgi apparatus);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0016192(vesicle-mediated transport);GO:0033116(endoplasmic reticulum-Golgi intermediate compartment membrane)","NA","NA","NA","ERGIC and golgi 3 [Source:HGNC Symbol;Acc:HGNC:15927]",{"v":0.012286,"d":"0.01"},{"v":1.02E-4,"d":"0.00"},{"v":120.450980392157,"d":"120.45"},{"v":6.91230232599243,"d":"6.91"},1,1,"up","no"]
[38774,0,"chr12","-",10127446,10130257,"ENST00000525605",3,573,"MSTRG.3163","CLEC7A","GO:0005737(cytoplasm);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0043231(intracellular membrane-bounded organelle);GO:0046872(metal ion binding);GO:0005654(nucleoplasm);GO:0030246(carbohydrate binding);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0002376(immune system process);GO:0045087(innate immune response);GO:0006954(inflammatory response);GO:0002221(pattern recognition receptor signaling pathway);GO:0002223(stimulatory C-type lectin receptor signaling pathway);GO:0042110(T cell activation);GO:0008329(signaling pattern recognition receptor activity);GO:0006910(phagocytosis, recognition);GO:0008037(cell recognition);GO:0042832(defense response to protozoan);GO:0042287(MHC protein binding);GO:0009756(carbohydrate mediated signaling)","04145(Phagosome);05152(Tuberculosis)","NA","NA","C-type lectin domain containing 7A [Source:HGNC Symbol;Acc:HGNC:14558]",{"v":0.176605,"d":"0.18"},{"v":1.140745,"d":"1.14"},{"v":0.15481549338371,"d":"0.15"},{"v":-2.69137823639379,"d":"-2.69"},1,1,"down","no"]
[152132,"j","chr4","-",168356741,168480567,"MSTRG.11913.5",38,6814,"MSTRG.11913","DDX60L","NA","NA","NA","NA","NA",{"v":0.07775,"d":"0.08"},{"v":0.493186,"d":"0.49"},{"v":0.157648432842781,"d":"0.16"},{"v":-2.66521726638965,"d":"-2.67"},1,1,"down","no"]
[9301,0,"chr1","+",112674698,112700734,"ENST00000369644",22,4100,"MSTRG.811","MOV10","GO:0003723(RNA binding);GO:0005737(cytoplasm);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0005829(cytosol);GO:0016787(hydrolase activity);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0004386(helicase activity);GO:0005515(protein binding);GO:0005615(extracellular space);GO:0031047(gene silencing by RNA);GO:0000932(P-body);GO:0038111(interleukin-7-mediated signaling pathway);GO:0048015(phosphatidylinositol-mediated signaling);GO:0045652(regulation of megakaryocyte differentiation);GO:0007223(Wnt signaling pathway, calcium modulating pathway);GO:0035195(gene silencing by miRNA);GO:0035279(mRNA cleavage involved in gene silencing by miRNA)","NA","NA","NA","Mov10 RISC complex RNA helicase [Source:HGNC Symbol;Acc:HGNC:7200]",0,0,1,0,1,1,"no","no"]
[169716,0,"chr6","-",139239083,139270561,"ENST00000621913",7,959,"MSTRG.13313","AL158850.2","NA","NA","NA","NA","NA",0,0,1,0,1,1,"no","no"]
[138741,0,"chr3","+",101827993,101861022,"ENST00000394054",13,3787,"MSTRG.11097","NFKBIZ","GO:0016607(nuclear speck);GO:0000932(P-body);GO:0005634(nucleus);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0005515(protein binding);GO:0006357(regulation of transcription from RNA polymerase II promoter);GO:0003712(transcription cofactor activity);GO:0006954(inflammatory response)","05202(Transcriptional misregulation in cancers)","K14242","NA","NFKB inhibitor zeta [Source:HGNC Symbol;Acc:HGNC:29805]",{"v":0.085325,"d":"0.09"},{"v":0.082978,"d":"0.08"},{"v":1.0282846055581,"d":"1.03"},{"v":0.0402396246483743,"d":"0.04"},1,1,"up","no"]
[103478,0,"chr19","-",48306300,48321894,"ENST00000504608",5,462,"MSTRG.8276","CCDC114","GO:0042995(cell projection);GO:0005515(protein binding);GO:0005929(cilium);GO:0036158(outer dynein arm assembly);GO:0003341(cilium movement);GO:0005930(axoneme);GO:0036157(outer dynein arm)","NA","NA","NA","coiled-coil domain containing 114 [Source:HGNC Symbol;Acc:HGNC:26560]",0,0,1,0,1,1,"no","no"]
[178707,0,"chr7","+",130207860,130216843,"ENST00000297819",3,1159,"ENSG00000165120","SSMEM1","GO:0016020(membrane);GO:0016021(integral component of membrane)","NA","NA","NA","serine rich single-pass membrane protein 1 [Source:HGNC Symbol;Acc:HGNC:29580]",0,{"v":0.039365,"d":"0.04"},"-inf","-inf",1,1,"down","no"]
[129917,0,"chr22","-",28687897,28734721,"ENST00000402731",13,1545,"ENSG00000183765","CHEK2","GO:0004672(protein kinase activity);GO:0005524(ATP binding);GO:0006468(protein phosphorylation);GO:0005794(Golgi apparatus);GO:0005654(nucleoplasm);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0000166(nucleotide binding);GO:0004674(protein serine/threonine kinase activity);GO:0016740(transferase activity);GO:0016301(kinase activity);GO:0016310(phosphorylation);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0051301(cell division);GO:0042803(protein homodimerization activity);GO:0005515(protein binding);GO:0006281(DNA repair);GO:0006974(cellular response to DNA damage stimulus);GO:0007049(cell cycle);GO:0006915(apoptotic process);GO:0045893(positive regulation of transcription, DNA-templated);GO:0042802(identical protein binding);GO:0006977(DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest);GO:0019901(protein kinase binding);GO:0050821(protein stabilization);GO:0044257(cellular protein catabolic process);GO:0031625(ubiquitin protein ligase binding);GO:0090307(mitotic spindle assembly);GO:0018105(peptidyl-serine phosphorylation);GO:1901796(regulation of signal transduction by p53 class mediator);GO:0042981(regulation of apoptotic process);GO:0016605(PML body);GO:0046777(protein autophosphorylation);GO:0090399(replicative senescence);GO:0000781(chromosome, telomeric region);GO:0000077(DNA damage checkpoint);GO:0006975(DNA damage induced protein phosphorylation);GO:0018107(peptidyl-threonine phosphorylation);GO:0000086(G2/M transition of mitotic cell cycle);GO:0006302(double-strand break repair);GO:0001302(replicative cell aging);GO:0008630(intrinsic apoptotic signaling pathway in response to DNA damage);GO:0042176(regulation of protein catabolic process);GO:0042770(signal transduction in response to DNA damage);GO:0072428(signal transduction involved in intra-S DNA damage checkpoint);GO:0001934(positive regulation of protein phosphorylation);GO:0006978(DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator);GO:0010332(response to gamma radiation);GO:0035690(cellular response to drug);GO:0042771(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator);GO:0071157(negative regulation of cell cycle arrest);GO:0071480(cellular response to gamma radiation);GO:1903416(response to glycoside);GO:1903926(cellular response to bisphenol A);GO:2000002(negative regulation of DNA damage checkpoint);GO:2000210(positive regulation of anoikis)","04110(Cell cycle);04115(p53 signaling pathway);04218(Cellular senescence);05166(HTLV-I infection)","NA","NA","checkpoint kinase 2 [Source:HGNC Symbol;Acc:HGNC:16627]",0,0,1,0,1,1,"no","no"]
[48778,0,"chr12","+",133038875,133048844,"ENST00000543310",4,562,"ENSG00000198040","ZNF84","GO:0003676(nucleic acid binding);GO:0046872(metal ion binding);GO:0006355(regulation of transcription, DNA-templated);GO:0005622(intracellular);GO:0005634(nucleus);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0008270(zinc ion binding);GO:0001570(vasculogenesis);GO:0001822(kidney development);GO:0006807(nitrogen compound metabolic process);GO:0009791(post-embryonic development);GO:0014909(smooth muscle cell migration);GO:0030097(hemopoiesis);GO:0035264(multicellular organism growth);GO:0048008(platelet-derived growth factor receptor signaling pathway);GO:0048705(skeletal system morphogenesis);GO:0048745(smooth muscle tissue development);GO:0060021(palate development);GO:0060325(face morphogenesis)","NA","NA","NA","zinc finger protein 84 [Source:HGNC Symbol;Acc:HGNC:13159]",{"v":0.135481,"d":"0.14"},0,"inf","inf",1,1,"up","no"]
[76732,0,"chr16","-",88656170,88658783,"ENST00000566636",3,863,"MSTRG.6227","MVD","GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0016829(lyase activity);GO:0006629(lipid metabolic process);GO:0005829(cytosol);GO:0042803(protein homodimerization activity);GO:0006694(steroid biosynthetic process);GO:0008202(steroid metabolic process);GO:0008299(isoprenoid biosynthetic process);GO:0016126(sterol biosynthetic process);GO:0008203(cholesterol metabolic process);GO:0016831(carboxy-lyase activity);GO:0006695(cholesterol biosynthetic process);GO:0008284(positive regulation of cell proliferation);GO:0045540(regulation of cholesterol biosynthetic process);GO:0030544(Hsp70 protein binding);GO:0004163(diphosphomevalonate decarboxylase activity);GO:0006489(dolichyl diphosphate biosynthetic process);GO:0019287(isopentenyl diphosphate biosynthetic process, mevalonate pathway)","00900(Terpenoid backbone biosynthesis)","NA","NA","mevalonate diphosphate decarboxylase [Source:HGNC Symbol;Acc:HGNC:7529]",0,{"v":0.256758,"d":"0.26"},"-inf","-inf",1,1,"down","no"]
[121025,0,"chr2","+",241150496,241167174,"ENST00000401987",8,820,"MSTRG.9523","PPP1R7","GO:0005634(nucleus);GO:0050790(regulation of catalytic activity);GO:0005515(protein binding);GO:0008150(biological_process);GO:0070062(extracellular exosome);GO:0005737(cytoplasm);GO:0019888(protein phosphatase regulator activity);GO:0030234(enzyme regulator activity);GO:0035307(positive regulation of protein dephosphorylation);GO:0005694(chromosome);GO:0007059(chromosome segregation);GO:0061588(calcium activated phospholipid scrambling)","NA","NA","NA","protein phosphatase 1 regulatory subunit 7 [Source:HGNC Symbol;Acc:HGNC:9295]",{"v":1.195418,"d":"1.20"},{"v":0.294962,"d":"0.29"},{"v":4.05278646062883,"d":"4.05"},{"v":2.01891416247881,"d":"2.02"},1,1,"up","no"]
[69645,0,"chr16","-",11402131,11414555,"ENST00000596416",4,518,"ENSG00000188897","AC099489.1","GO:0006869(lipid transport);GO:0005319(lipid transporter activity)","NA","NA","NA","NA",{"v":0.109238,"d":"0.11"},{"v":0.030443,"d":"0.03"},{"v":3.58827973589988,"d":"3.59"},{"v":1.84329236457829,"d":"1.84"},1,1,"up","no"]
[96992,0,"chr19","-",12319179,12333492,"ENST00000594577",5,749,"ENSG00000188868","ZNF563","GO:0003676(nucleic acid binding);GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0006355(regulation of transcription, DNA-templated);GO:0006351(transcription, DNA-templated);GO:0003677(DNA binding);GO:0005622(intracellular)","NA","NA","NA","zinc finger protein 563 [Source:HGNC Symbol;Acc:HGNC:30498]",{"v":0.100055,"d":"0.10"},0,"inf","inf",1,1,"up","no"]
[142219,0,"chr3","-",160256992,160383656,"ENST00000483465",19,4044,"ENSG00000068885","IFT80","GO:0005737(cytoplasm);GO:0005856(cytoskeleton);GO:0042995(cell projection);GO:0005813(centrosome);GO:0035735(intraciliary transport involved in cilium assembly);GO:0005929(cilium);GO:0030992(intraciliary transport particle B);GO:0097542(ciliary tip);GO:0060271(cilium assembly)","NA","NA","NA","intraflagellar transport 80 [Source:HGNC Symbol;Acc:HGNC:29262]",0,{"v":1.208495,"d":"1.21"},"-inf","-inf",1,1,"down","no"]
[53115,0,"chr14","-",22998773,23010143,"ENST00000553958",3,588,"ENSG00000100802","C14orf93","GO:0003723(RNA binding);GO:0005515(protein binding);GO:0005576(extracellular region)","NA","NA","NA","chromosome 14 open reading frame 93 [Source:HGNC Symbol;Acc:HGNC:20162]",{"v":0.169539,"d":"0.17"},0,"inf","inf",1,1,"up","no"]
[131561,0,"chr22","+",40346530,40361577,"ENST00000623287",7,856,"MSTRG.10502","ADSL","GO:0003824(catalytic activity);GO:0016829(lyase activity);GO:0006164(purine nucleotide biosynthetic process);GO:0044208('de novo' AMP biosynthetic process);GO:0004018(N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity);GO:0070626((S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido)succinate AMP-lyase (fumarate-forming) activity);GO:0006189('de novo' IMP biosynthetic process);GO:0009152(purine ribonucleotide biosynthetic process);GO:0005829(cytosol);GO:0009168(purine ribonucleoside monophosphate biosynthetic process);GO:0051262(protein tetramerization);GO:0006167(AMP biosynthetic process);GO:0001666(response to hypoxia);GO:0006163(purine nucleotide metabolic process);GO:0007584(response to nutrient);GO:0009060(aerobic respiration);GO:0009156(ribonucleoside monophosphate biosynthetic process);GO:0014850(response to muscle activity);GO:0042594(response to starvation);GO:0005739(mitochondrion)","00230(Purine metabolism);00250(Alanine, aspartate and glutamate metabolism)","NA","NA","adenylosuccinate lyase [Source:HGNC Symbol;Acc:HGNC:291]",0,0,1,0,1,1,"no","no"]
[23132,0,"chr10","-",102480795,102484374,"ENST00000494549",4,520,"MSTRG.1934","ACTR1A","GO:0005869(dynactin complex);GO:0005737(cytoplasm);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0015630(microtubule cytoskeleton);GO:0005856(cytoskeleton);GO:0005813(centrosome);GO:0005815(microtubule organizing center);GO:0005515(protein binding);GO:0005829(cytosol);GO:0070062(extracellular exosome);GO:0005938(cell cortex);GO:0000086(G2/M transition of mitotic cell cycle);GO:0010389(regulation of G2/M transition of mitotic cell cycle);GO:0097711(ciliary basal body docking);GO:0019886(antigen processing and presentation of exogenous peptide antigen via MHC class II);GO:0016192(vesicle-mediated transport);GO:0006888(ER to Golgi vesicle-mediated transport);GO:0005875(microtubule associated complex);GO:0099738(cell cortex region);GO:0007283(spermatogenesis);GO:0002177(manchette);GO:0005814(centriole);GO:0030137(COPI-coated vesicle);GO:0043209(myelin sheath)","NA","NA","NA","ARP1 actin related protein 1 homolog A [Source:HGNC Symbol;Acc:HGNC:167]",{"v":0.536229,"d":"0.54"},{"v":0.444985,"d":"0.44"},{"v":1.20504960841377,"d":"1.21"},{"v":0.269092539267972,"d":"0.27"},1,1,"up","no"]
[183501,0,"chr8","+",42697419,42737407,"ENST00000289957",6,2294,"ENSG00000147432","CHRNB3","GO:0006810(transport);GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0005216(ion channel activity);GO:0006811(ion transport);GO:0005886(plasma membrane);GO:0030054(cell junction);GO:0045202(synapse);GO:0045211(postsynaptic membrane);GO:0005230(extracellular ligand-gated ion channel activity);GO:0060079(excitatory postsynaptic potential);GO:0060078(regulation of postsynaptic membrane potential);GO:0022848(acetylcholine-gated cation-selective channel activity);GO:0007165(signal transduction);GO:0015267(channel activity);GO:0007274(neuromuscular synaptic transmission);GO:0042166(acetylcholine binding);GO:0015276(ligand-gated ion channel activity);GO:0035094(response to nicotine);GO:0005892(acetylcholine-gated channel complex);GO:0098655(cation transmembrane transport);GO:0007271(synaptic transmission, cholinergic);GO:0008144(drug binding);GO:0051291(protein heterooligomerization);GO:0043005(neuron projection)","04080(Neuroactive ligand-receptor interaction)","K04814","NA","cholinergic receptor nicotinic beta 3 subunit [Source:HGNC Symbol;Acc:HGNC:1963]",{"v":0.071195,"d":"0.07"},{"v":0.021082,"d":"0.02"},{"v":3.37705151313917,"d":"3.38"},{"v":1.75576418621054,"d":"1.76"},1,1,"up","no"]
[140487,0,"chr3","+",130560334,130678155,"ENST00000358511",36,9581,"ENSG00000206384","COL6A6","GO:0007155(cell adhesion);GO:0005576(extracellular region);GO:0005581(collagen trimer);GO:0005578(proteinaceous extracellular matrix);GO:0030574(collagen catabolic process)","04151(PI3K-Akt signaling pathway);04512(ECM-receptor interaction);04510(Focal adhesion);04974(Protein digestion and absorption);05165(Human papillomavirus infection)","K06238","NA","collagen type VI alpha 6 chain [Source:HGNC Symbol;Acc:HGNC:27023]",{"v":0.027991,"d":"0.03"},{"v":0.033119,"d":"0.03"},{"v":0.845164407137897,"d":"0.85"},{"v":-0.242696083325453,"d":"-0.24"},1,1,"down","no"]
[84074,0,"chr17","+",44115912,44120595,"ENST00000585899",3,359,"MSTRG.6885","AC023855.1","NA","NA","NA","NA","NA",{"v":0.120628,"d":"0.12"},{"v":0.246439,"d":"0.25"},{"v":0.48948421313185,"d":"0.49"},{"v":-1.03066576417722,"d":"-1.03"},1,1,"down","no"]
[92089,0,"chr18","-",45857822,45916454,"ENST00000590884",23,3767,"ENSG00000152223","EPG5","GO:0006914(autophagy);GO:0005737(cytoplasm);GO:0097352(autophagosome maturation);GO:0032456(endocytic recycling)","NA","NA","NA","ectopic P-granules autophagy protein 5 homolog [Source:HGNC Symbol;Acc:HGNC:29331]",{"v":0.016353,"d":"0.02"},{"v":0.624363,"d":"0.62"},{"v":0.026191494371063,"d":"0.03"},{"v":-5.25475781392673,"d":"-5.25"},1,1,"down","no"]
[129015,0,"chr22","-",21491976,21514223,"ENST00000491562",2,209,"ENSG00000183506","PI4KAP2","NA","NA","NA","NA","phosphatidylinositol 4-kinase alpha pseudogene 2 [Source:HGNC Symbol;Acc:HGNC:33577]",0,0,1,0,1,1,"no","no"]
[10929,0,"chr1","-",151612038,151613363,"ENST00000504583",2,535,"MSTRG.957","AL391335.1","NA","NA","NA","NA","NA",0,{"v":0.034396,"d":"0.03"},"-inf","-inf",1,1,"down","no"]
[66585,0,"chr15","-",90981963,90994500,"ENST00000559811",4,414,"ENSG00000198901","PRC1","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005654(nucleoplasm);GO:0051301(cell division);GO:0005886(plasma membrane);GO:0015630(microtubule cytoskeleton);GO:0005856(cytoskeleton);GO:0005515(protein binding);GO:0007049(cell cycle);GO:0008017(microtubule binding);GO:0001578(microtubule bundle formation);GO:0005874(microtubule);GO:0000226(microtubule cytoskeleton organization);GO:0000922(spindle pole);GO:0005819(spindle);GO:0030496(midbody);GO:0000910(cytokinesis);GO:0005829(cytosol);GO:0019901(protein kinase binding);GO:0008284(positive regulation of cell proliferation);GO:0019894(kinesin binding);GO:0000022(mitotic spindle elongation);GO:0005876(spindle microtubule);GO:0070938(contractile ring)","NA","NA","NA","protein regulator of cytokinesis 1 [Source:HGNC Symbol;Acc:HGNC:9341]",{"v":0.008098,"d":"0.01"},0,"inf","inf",1,1,"up","no"]
[160141,0,"chr5","-",151029949,151087158,"ENST00000315050",18,2785,"MSTRG.12464","TNIP1","GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0005654(nucleoplasm);GO:0005515(protein binding);GO:0002755(MyD88-dependent toll-like receptor signaling pathway);GO:0006954(inflammatory response);GO:0042802(identical protein binding);GO:0050727(regulation of inflammatory response);GO:0043124(negative regulation of I-kappaB kinase/NF-kappaB signaling);GO:0070373(negative regulation of ERK1 and ERK2 cascade);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0005622(intracellular);GO:0016579(protein deubiquitination);GO:0045071(negative regulation of viral genome replication);GO:0050729(positive regulation of inflammatory response);GO:0006412(translation);GO:0006952(defense response);GO:0051019(mitogen-activated protein kinase binding);GO:0009101(glycoprotein biosynthetic process);GO:0007159(leukocyte cell-cell adhesion);GO:0031593(polyubiquitin binding);GO:0071222(cellular response to lipopolysaccharide);GO:0085032(modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade);GO:1903003(positive regulation of protein deubiquitination)","NA","NA","NA","TNFAIP3 interacting protein 1 [Source:HGNC Symbol;Acc:HGNC:16903]",0,{"v":0.001095,"d":"0.00"},"-inf","-inf",1,1,"down","no"]
[42251,0,"chr12","+",53501332,53503472,"ENST00000547388",2,576,"MSTRG.3417","TARBP2","GO:0003723(RNA binding);GO:0003725(double-stranded RNA binding);GO:0016442(RISC complex);GO:0030422(production of siRNA involved in RNA interference);GO:0035197(siRNA binding);GO:0031054(pre-miRNA processing);GO:0035280(miRNA loading onto RISC involved in gene silencing by miRNA);GO:0046782(regulation of viral transcription);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0005654(nucleoplasm);GO:0042803(protein homodimerization activity);GO:0005515(protein binding);GO:0016604(nuclear body);GO:0048471(perinuclear region of cytoplasm);GO:0031047(gene silencing by RNA);GO:0042802(identical protein binding);GO:0005829(cytosol);GO:0006417(regulation of translation);GO:0035087(siRNA loading onto RISC involved in RNA interference);GO:0019899(enzyme binding);GO:0006469(negative regulation of protein kinase activity);GO:0047485(protein N-terminus binding);GO:0045070(positive regulation of viral genome replication);GO:0070883(pre-miRNA binding);GO:0010586(miRNA metabolic process);GO:0035196(production of miRNAs involved in gene silencing by miRNA);GO:0070578(RISC-loading complex);GO:0036002(pre-mRNA binding);GO:0007286(spermatid development);GO:0007338(single fertilization);GO:0030423(targeting of mRNA for destruction involved in RNA interference);GO:0035264(multicellular organism growth);GO:0045727(positive regulation of translation);GO:0050689(negative regulation of defense response to virus by host);GO:0035068(micro-ribonucleoprotein complex)","NA","NA","NA","TARBP2, RISC loading complex RNA binding subunit [Source:HGNC Symbol;Acc:HGNC:11569]",0,{"v":0.16459,"d":"0.16"},"-inf","-inf",1,1,"down","no"]
[20673,0,"chr10","-",63219877,63521850,"ENST00000633035",4,499,"MSTRG.1732","JMJD1C","GO:0005634(nucleus);GO:0046872(metal ion binding);GO:0016491(oxidoreductase activity);GO:0055114(oxidation-reduction process);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0016569(covalent chromatin modification);GO:0005515(protein binding);GO:0051213(dioxygenase activity);GO:0005654(nucleoplasm);GO:0005622(intracellular);GO:0000976(transcription regulatory region sequence-specific DNA binding);GO:0007596(blood coagulation);GO:0000785(chromatin);GO:0031490(chromatin DNA binding);GO:0032454(histone demethylase activity (H3-K9 specific));GO:0033169(histone H3-K9 demethylation);GO:0046966(thyroid hormone receptor binding)","05202(Transcriptional misregulation in cancers)","NA","NA","jumonji domain containing 1C [Source:HGNC Symbol;Acc:HGNC:12313]",{"v":0.147315,"d":"0.15"},{"v":0.773601,"d":"0.77"},{"v":0.190427623542369,"d":"0.19"},{"v":-2.3926853228752,"d":"-2.39"},1,1,"down","no"]
[117003,0,"chr2","+",181457202,181459391,"ENST00000476089",2,1846,"MSTRG.9287","ITGA4","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0046872(metal ion binding);GO:0007155(cell adhesion);GO:0005886(plasma membrane);GO:0005515(protein binding);GO:0007229(integrin-mediated signaling pathway);GO:0008305(integrin complex);GO:0005925(focal adhesion);GO:0050776(regulation of immune response);GO:0050900(leukocyte migration);GO:0070062(extracellular exosome);GO:0009986(cell surface);GO:0030198(extracellular matrix organization);GO:0043113(receptor clustering);GO:0007160(cell-matrix adhesion);GO:0015026(coreceptor activity);GO:0050839(cell adhesion molecule binding);GO:0034446(substrate adhesion-dependent cell spreading);GO:0035987(endodermal cell differentiation);GO:0019960(C-X3-C chemokine binding);GO:0034113(heterotypic cell-cell adhesion);GO:0007159(leukocyte cell-cell adhesion);GO:0030183(B cell differentiation);GO:0050901(leukocyte tethering or rolling);GO:0003366(cell-matrix adhesion involved in ameboidal cell migration);GO:0090074(negative regulation of protein homodimerization activity);GO:0034669(integrin alpha4-beta7 complex);GO:0001968(fibronectin binding);GO:0003823(antigen binding);GO:1990405(protein antigen binding);GO:0002687(positive regulation of leukocyte migration);GO:0050904(diapedesis);GO:0071345(cellular response to cytokine stimulus);GO:0098657(import into cell);GO:1903039(positive regulation of leukocyte cell-cell adhesion);GO:1903238(positive regulation of leukocyte tethering or rolling);GO:1990771(clathrin-dependent extracellular exosome endocytosis);GO:2000406(positive regulation of T cell migration)","04151(PI3K-Akt signaling pathway);04512(ECM-receptor interaction);04514(Cell adhesion molecules (CAMs));04510(Focal adhesion);04810(Regulation of actin cytoskeleton);04640(Hematopoietic cell lineage);04670(Leukocyte transendothelial migration);04672(Intestinal immune network for IgA production);05410(Hypertrophic cardiomyopathy (HCM));05412(Arrhythmogenic right ventricular cardiomyopathy (ARVC));05414(Dilated cardiomyopathy (DCM));05165(Human papillomavirus infection);05140(Leishmaniasis)","NA","NA","integrin subunit alpha 4 [Source:HGNC Symbol;Acc:HGNC:6140]",{"v":0.090571,"d":"0.09"},{"v":0.325171,"d":"0.33"},{"v":0.27853344855476,"d":"0.28"},{"v":-1.84407750640115,"d":"-1.84"},1,1,"down","no"]
[30985,0,"chr11","-",65045313,65047886,"ENST00000532802",4,566,"ENSG00000168060","NAALADL1","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0046872(metal ion binding);GO:0016787(hydrolase activity);GO:0005886(plasma membrane);GO:0003824(catalytic activity);GO:0008152(metabolic process);GO:0008233(peptidase activity);GO:0006508(proteolysis);GO:0004180(carboxypeptidase activity);GO:0008237(metallopeptidase activity);GO:0016805(dipeptidase activity);GO:0016324(apical plasma membrane)","NA","NA","NA","N-acetylated alpha-linked acidic dipeptidase like 1 [Source:HGNC Symbol;Acc:HGNC:23536]",0,{"v":0.104152,"d":"0.10"},"-inf","-inf",1,1,"down","no"]
[12710,0,"chr1","-",160950553,160951474,"ENST00000490489",2,591,"ENSG00000158764","ITLN2","GO:0046872(metal ion binding);GO:0030246(carbohydrate binding);GO:0005576(extracellular region)","NA","NA","NA","intelectin 2 [Source:HGNC Symbol;Acc:HGNC:20599]",0,0,1,0,1,1,"no","no"]
[4590,0,"chr1","-",39569495,39569990,"ENST00000492519",2,323,"MSTRG.440","PABPC4","GO:0003723(RNA binding);GO:0003676(nucleic acid binding);GO:0005737(cytoplasm);GO:0005829(cytosol);GO:0030529(intracellular ribonucleoprotein complex);GO:0005515(protein binding);GO:0007596(blood coagulation);GO:0005634(nucleus);GO:0006412(translation);GO:0006401(RNA catabolic process);GO:0006396(RNA processing);GO:0008143(poly(A) binding);GO:0008266(poly(U) RNA binding);GO:0010494(cytoplasmic stress granule)","03013(RNA transport);03015(mRNA surveillance pathway);03018(RNA degradation)","NA","NA","poly(A) binding protein cytoplasmic 4 [Source:HGNC Symbol;Acc:HGNC:8557]",0,{"v":0.008977,"d":"0.01"},"-inf","-inf",1,1,"down","no"]
[141866,0,"chr3","-",154276029,154277835,"ENST00000495598",3,719,"ENSG00000174953","DHX36","GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0000166(nucleotide binding);GO:0005524(ATP binding);GO:0005829(cytosol);GO:0016787(hydrolase activity);GO:0006351(transcription, DNA-templated);GO:0006355(regulation of transcription, DNA-templated);GO:0004386(helicase activity);GO:0003677(DNA binding);GO:0005694(chromosome);GO:0000781(chromosome, telomeric region);GO:0005515(protein binding);GO:0001047(core promoter binding);GO:0045944(positive regulation of transcription from RNA polymerase II promoter);GO:0070062(extracellular exosome);GO:0004004(ATP-dependent RNA helicase activity);GO:0001503(ossification);GO:0044212(transcription regulatory region DNA binding);GO:0010501(RNA secondary structure unwinding);GO:0070034(telomerase RNA binding);GO:0032481(positive regulation of type I interferon production);GO:0003697(single-stranded DNA binding);GO:0008094(DNA-dependent ATPase activity);GO:0042826(histone deacetylase binding);GO:0003725(double-stranded RNA binding);GO:0090669(telomerase RNA stabilization);GO:1902741(positive regulation of interferon-alpha secretion);GO:0051880(G-quadruplex DNA binding);GO:0032206(positive regulation of telomere maintenance);GO:0002151(G-quadruplex RNA binding);GO:0006396(RNA processing);GO:0009615(response to virus);GO:0043330(response to exogenous dsRNA);GO:0016020(membrane);GO:0016021(integral component of membrane)","03018(RNA degradation)","NA","NA","DEAH-box helicase 36 [Source:HGNC Symbol;Acc:HGNC:14410]",0,{"v":0.052616,"d":"0.05"},"-inf","-inf",1,1,"down","no"]
[188607,0,"chr9","-",121089,179012,"ENST00000612045",16,1813,"MSTRG.14648","CBWD1","GO:0000166(nucleotide binding);GO:0005524(ATP binding)","NA","NA","NA","COBW domain containing 1 [Source:HGNC Symbol;Acc:HGNC:17134]",0,0,1,0,1,1,"no","no"]
[46759,0,"chr12","+",111744571,111747208,"ENST00000546647",3,774,"MSTRG.3726","ACAD10","GO:0008152(metabolic process);GO:0016787(hydrolase activity);GO:0016491(oxidoreductase activity);GO:0050660(flavin adenine dinucleotide binding);GO:0055114(oxidation-reduction process);GO:0016627(oxidoreductase activity, acting on the CH-CH group of donors);GO:0005739(mitochondrion);GO:0005759(mitochondrial matrix);GO:0006635(fatty acid beta-oxidation);GO:0003995(acyl-CoA dehydrogenase activity);GO:0033539(fatty acid beta-oxidation using acyl-CoA dehydrogenase)","NA","NA","NA","acyl-CoA dehydrogenase family member 10 [Source:HGNC Symbol;Acc:HGNC:21597]",{"v":1.6e-05,"d":"0.00"},{"v":0.17578,"d":"0.18"},{"v":9.10228694959609e-05,"d":"0.00"},{"v":-13.4234114064526,"d":"-13.42"},1,1,"down","no"]
[138775,0,"chr3","+",105550220,105553171,"ENST00000489178",3,783,"ENSG00000170017","ALCAM","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0007155(cell adhesion);GO:0005886(plasma membrane);GO:0042995(cell projection);GO:0005515(protein binding);GO:0005576(extracellular region);GO:0002376(immune system process);GO:0005925(focal adhesion);GO:0030425(dendrite);GO:0002250(adaptive immune response);GO:0005887(integral component of plasma membrane);GO:0030424(axon);GO:0070062(extracellular exosome);GO:0007165(signal transduction);GO:0031226(intrinsic component of plasma membrane);GO:0005102(receptor binding);GO:0001772(immunological synapse);GO:0048846(axon extension involved in axon guidance);GO:0031290(retinal ganglion cell axon guidance);GO:0007157(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules);GO:0042101(T cell receptor complex);GO:1990138(neuron projection extension);GO:0007411(axon guidance);GO:0008045(motor neuron axon guidance);GO:0009897(external side of plasma membrane);GO:0043025(neuronal cell body)","04514(Cell adhesion molecules (CAMs))","NA","NA","activated leukocyte cell adhesion molecule [Source:HGNC Symbol;Acc:HGNC:400]",0,0,1,0,1,1,"no","no"]
[57514,0,"chr14","+",88572048,88611888,"ENST00000556000",13,2092,"ENSG00000100722","ZC3H14","GO:0003723(RNA binding);GO:0005634(nucleus);GO:0005737(cytoplasm);GO:0016607(nuclear speck);GO:0046872(metal ion binding);GO:0005730(nucleolus);GO:0005515(protein binding);GO:0043488(regulation of mRNA stability);GO:0008143(poly(A) binding);GO:1900364(negative regulation of mRNA polyadenylation)","NA","NA","NA","zinc finger CCCH-type containing 14 [Source:HGNC Symbol;Acc:HGNC:20509]",{"v":7.868E-3,"d":"0.01"},{"v":0.023444,"d":"0.02"},{"v":0.335608257976455,"d":"0.34"},{"v":-1.57514987972017,"d":"-1.58"},1,1,"down","no"]
[30370,0,"chr11","-",62798845,62805440,"ENST00000526163",3,569,"MSTRG.2479","NXF1","GO:0005634(nucleus);GO:0003676(nucleic acid binding);GO:0003723(RNA binding);GO:0006810(transport);GO:0051028(mRNA transport);GO:0005737(cytoplasm);GO:0016607(nuclear speck);GO:0005654(nucleoplasm);GO:0005622(intracellular);GO:0005515(protein binding);GO:0006406(mRNA export from nucleus);GO:0005829(cytosol);GO:0016032(viral process);GO:0006405(RNA export from nucleus);GO:0000346(transcription export complex);GO:0003727(single-stranded RNA binding);GO:0016973(poly(A)+ mRNA export from nucleus);GO:0003729(mRNA binding);GO:0005487(nucleocytoplasmic transporter activity);GO:0005643(nuclear pore);GO:0042405(nuclear inclusion body)","03013(RNA transport);03015(mRNA surveillance pathway);03008(Ribosome biogenesis in eukaryotes);05164(Influenza A);05168(Herpes simplex infection)","NA","NA","nuclear RNA export factor 1 [Source:HGNC Symbol;Acc:HGNC:8071]",{"v":0.223152,"d":"0.22"},{"v":0.241464,"d":"0.24"},{"v":0.924162608090647,"d":"0.92"},{"v":-0.113781376096501,"d":"-0.11"},1,1,"down","no"]
[36644,0,"chr11","+",125592867,125620888,"ENST00000531491",17,2160,"MSTRG.2953","STT3A","GO:0016020(membrane);GO:0016021(integral component of membrane);GO:0006486(protein glycosylation);GO:0004576(oligosaccharyl transferase activity);GO:0046872(metal ion binding);GO:0016740(transferase activity);GO:0016757(transferase activity, transferring glycosyl groups);GO:0005783(endoplasmic reticulum);GO:0005789(endoplasmic reticulum membrane);GO:0005515(protein binding);GO:0018279(protein N-linked glycosylation via asparagine);GO:0004579(dolichyl-diphosphooligosaccharide-protein glycotransferase activity);GO:0008250(oligosaccharyltransferase complex);GO:0043686(co-translational protein modification);GO:0043687(post-translational protein modification)","00510(N-Glycan biosynthesis);04141(Protein processing in endoplasmic reticulum)","K07151","EC:2.4.99.18","STT3A, catalytic subunit of the oligosaccharyltransferase complex [Source:HGNC Symbol;Acc:HGNC:6172]",0,{"v":1.456413,"d":"1.46"},"-inf","-inf",1,1,"down","no"]

{"sheet":"Table 9","index":8,"n_rows":2023,"n_cols":11,"rows_kept":2023}
["chr","start","end","gene_name","FPKM.T3","FPKM.T4","foldChange","foldChange2","qval","regulation","significant"]
["chr1",24899511,24965010,"RUNX3",0.2,27.75,139.43,7.12,0,"up","yes"]
["chr11",123057497,123061332,"HSPA8",0.43,39.36,91.42,6.51,0,"up","yes"]
["chr19",36139631,36150356,"CAPNS1",0.58,53.83,92.26,6.53,0,"up","yes"]
["chr1",35176372,35193148,"SFPQ",0.08,6.94,82.46,6.37,0,"up","yes"]
["chr14",105703995,105863312,"IGHA1",3.1,230.97,74.51,6.22,0,"up","yes"]
["chr16",74447589,74607097,"GLG1",0.14,10.21,73.67,6.2,0,"up","yes"]
["chr21",8210384,8211306,"FP671120.3",1.28,79.97,62.54,5.97,0,"up","yes"]
["chr1",101236888,101241518,"S1PR1",0.76,43.76,57.75,5.85,0,"up","yes"]
["chr5",96663053,96776973,"CAST",0.27,15.75,59.16,5.89,0,"up","yes"]
["chr21",8437629,8438551,"FP236383.3",1.78,100.74,56.47,5.82,0,"up","yes"]
["chr4",73980183,73988283,"PPBP",0.61,32.55,53.14,5.73,0,"up","yes"]
["chr11",83156988,83187451,"PCF11",0.1,5.5,52.53,5.71,0,"up","yes"]
["chr6",4021267,4064982,"PRPF4B",0.1,5.17,51.19,5.68,0,"up","yes"]
["chr15",43792337,43796089,"SERF2",0.47,23.47,49.86,5.64,0,"up","yes"]
["chr2",152655683,152717831,"PRPF40A",0.2,8.47,43.26,5.43,0,"up","yes"]
["chr11",128460244,128522201,"ETS1",0.23,9.19,39.88,5.32,0,"up","yes"]
["chr9",111360693,111484745,"KIAA0368",0.09,3.6,40.04,5.32,0,"up","yes"]
["chr11",45932712,46121174,"PHF21A",0.24,9.34,38.97,5.28,0,"up","yes"]
["chr17",49289208,49361993,"ZNF652",0.16,6.37,38.83,5.28,0,"up","yes"]
["chr12",91987977,92145897,"LINC01619",0.88,31.73,36.04,5.17,0,"up","yes"]
["chr12",108622277,108633959,"SELPLG",3.67,130.5,35.53,5.15,0,"up","yes"]
["chr10",29458059,29634972,"SVIL",0.12,4.49,37.89,5.24,0,"up","yes"]
["chr3",197671393,197749699,"RUBCN",0.12,4.13,35.05,5.13,0,"up","yes"]
["chr15",82536755,82540457,"RPS17",4.98,161.52,32.41,5.02,0,"up","yes"]
["chr17",50719570,50750996,"LUC7L3",0.31,10.59,34.34,5.1,0,"up","yes"]
["chr21",8393419,8394341,"FP236383.2",0.93,31.02,33.38,5.06,0,"up","yes"]
["chr2",24554453,24770702,"NCOA1",0.31,9.12,29.4,4.88,0,"up","yes"]
["chr17",16029010,16215539,"NCOR1",0.26,7.48,28.69,4.84,0,"up","yes"]
["chr6",30676389,30691484,"NRM",0.41,11.75,28.67,4.84,0,"up","yes"]
["chr1",47183556,47211926,"PDZK1IP1",0.6,17.84,29.55,4.88,0,"up","yes"]
["chr12",10372346,10409769,"KLRC4-KLRK1",0.8,22.4,27.96,4.81,0,"up","yes"]
["chr9",95443412,95506599,"PTCH1",0.07,2.13,28.88,4.85,0,"up","yes"]
["chr22",22409770,22901438,"IGLL5",0.88,24.91,28.22,4.82,0,"up","yes"]
["chr22",37849481,37888630,"EIF3L",0.88,23.41,26.76,4.74,0,"up","yes"]
["chr22",40410281,40636685,"MKL1",0.26,7.06,27.28,4.77,0,"up","yes"]
["chr20",56359109,56360712,"FAM210B",2.76,71.9,26.08,4.7,0,"up","yes"]
["chr19",2101350,2137093,"AP3D1",0.33,8.58,25.82,4.69,0,"up","yes"]
["chr5",14708397,14871834,"ANKH",0.14,3.82,26.67,4.74,0,"up","yes"]
["chr16",88570381,88631966,"ZC3H18",0.22,5.69,26.04,4.7,0,"up","yes"]
["chr2",170990823,171160833,"TLK1",0.12,3.12,26.01,4.7,0,"up","yes"]
["chr11",65497762,65506469,"MALAT1",2.28,52.67,23.11,4.53,0,"up","yes"]
["chr1",155689083,155738526,"DAP3",0.48,11.9,24.72,4.63,0,"up","yes"]
["chr2",101697931,101891869,"MAP4K4",0.64,15.18,23.57,4.56,0,"up","yes"]
["chr17",29071124,29180412,"MYO18A",0.17,3.96,23.41,4.55,0,"up","yes"]
["chr8",22053570,22082524,"DMTN",0.55,12.84,23.52,4.56,0,"up","yes"]
["chr8",23541445,23572237,"SLC25A37",1.14,25.83,22.69,4.5,0,"up","yes"]
["chr12",49185010,49186864,"TUBA1A",0.69,16.33,23.81,4.57,0,"up","yes"]
["chr6",53267398,53349179,"ELOVL5",0.23,5.41,23.6,4.56,0,"up","yes"]
["chr4",38795974,38845886,"TLR1",0.22,4.91,22.25,4.48,0,"up","yes"]
["chr9",136114581,136118863,"TMEM250",0.38,8.54,22.64,4.5,0,"up","yes"]
["chr17",50719580,50750996,"LUC7L3",0.51,11.52,22.41,4.49,0,"up","yes"]
["chr1",6186723,6199553,"RPL22",2.88,63.48,22.05,4.46,0,"up","yes"]
["chr20",35277342,35278129,"MMP24-AS1",1.37,30.11,22.05,4.46,0,"up","yes"]
["chr12",124324415,124495252,"NCOR2",0.29,6.09,20.8,4.38,0,"up","yes"]
["chr1",42682987,42702349,"YBX1",8.03,162.49,20.23,4.34,0,"up","yes"]
["chr8",56067295,56074509,"RPS20",2.13,42.98,20.17,4.33,0,"up","yes"]
["chr14",74781385,74836190,"YLPM1",0.17,3.59,20.92,4.39,0,"up","yes"]
["chr12",108622829,108632078,"SELPLG",1.14,22.97,20.14,4.33,0,"up","yes"]
["chr9",107283279,107332194,"RAD23B",0.27,5.63,20.54,4.36,0,"up","yes"]
["chr6",159679064,159693234,"SOD2",2.64,52.25,19.76,4.3,0,"up","yes"]
["chr11",123057492,123063198,"HSPA8",1.39,27.12,19.44,4.28,0,"up","yes"]
["chr17",76734147,76736555,"SRSF2",0.44,9.22,20.96,4.39,0,"up","yes"]
["chr3",183919934,184018015,"ABCC5",0.12,2.48,20.94,4.39,0,"up","yes"]
["chr5",112707521,112844904,"APC",0.12,2.35,20.11,4.33,0,"up","yes"]
["chr17",38850114,38853737,"RPL23",1.79,35.67,19.9,4.31,0,"up","yes"]
["chr17",44205121,44220899,"UBTF",0.16,3.22,20.18,4.33,0,"up","yes"]
["chr20",59123381,59259113,"ZNF831",0.08,1.53,20.08,4.33,0,"up","yes"]
["chr2",144389213,144520119,"ZEB2",0.2,3.97,19.76,4.3,0,"up","yes"]
["chr14",23559565,23568070,"AP1G2",0.22,4.34,20.06,4.33,0,"up","yes"]
["chr2",230176789,230218065,"SP110",0.56,10.48,18.72,4.23,0,"up","yes"]
["chr1",16985958,17011772,"ATP13A2",0.24,4.51,19.16,4.26,0,"up","yes"]
["chr3",18347517,18445547,"SATB1",0.4,7.42,18.35,4.2,0,"up","yes"]
["chr19",8321634,8322396,"RPS28",13.03,228.55,17.54,4.13,0,"up","yes"]
["chr1",200969390,201023700,"KIF21B",0.26,4.6,17.61,4.14,0,"up","yes"]
["chr22",50525752,50530056,"TYMP",0.77,13.86,18.06,4.17,0,"up","yes"]
["chr17",7240413,7251965,"CTDNEP1",2.01,34.68,17.22,4.11,0,"up","yes"]
["chr11",64727032,64744633,"RASGRP2",0.94,16.02,17.06,4.09,0,"up","yes"]
["chr17",44308559,44318671,"RUNDC3A",0.76,12.99,17.15,4.1,0,"up","yes"]
["chr15",82536759,82540131,"RPS17",1.57,27.55,17.57,4.13,0,"up","yes"]
["chr2",159771851,159904710,"LY75-CD302",0.14,2.47,17.68,4.14,0,"up","yes"]
["chr19",1010695,1020942,"TMEM259",1.88,31.2,16.59,4.05,0,"up","yes"]
["chr16",83298,138361,"NPRL3",1.94,31.67,16.34,4.03,0,"up","yes"]
["chr4",849278,932373,"GAK",0.29,4.85,16.54,4.05,0,"up","yes"]
["chr17",40554330,40561013,"CCR7",0.44,7.45,16.98,4.09,0,"up","yes"]
["chr17",82233687,82240086,"SLC16A3",0.3,4.89,16.1,4.01,0,"up","yes"]
["chr11",72814427,72829633,"ATG16L2",0.22,3.71,16.52,4.05,0,"up","yes"]
["chr17",16438993,16441570,"LRRC75A-AS1",3,47.25,15.76,3.98,0,"up","yes"]
["chr13",40469953,40611129,"FOXO1",0.52,8.45,16.13,4.01,0,"up","yes"]
["chr1",158179947,158184896,"CD1D",0.36,5.88,16.23,4.02,0,"up","yes"]
["chr11",10852864,10858036,"ZBED5",0.44,6.96,15.92,3.99,0,"up","yes"]
["chr11",10797014,10808983,"EIF4G2",0.97,14.75,15.26,3.93,0,"up","yes"]
["chr12",79797234,79935130,"PPP1R12A",0.35,5.59,16.04,4,0,"up","yes"]
["chr17",44350539,44353043,"GRN",1.19,18.16,15.25,3.93,0,"up","yes"]
["chrX",63426560,63561049,"LINC01278",0.26,4.15,16.15,4.01,0,"up","yes"]
["chr19",19645203,19655451,"ATP13A1",0.28,4.54,16.18,4.02,0,"up","yes"]
["chr8",56073316,56074498,"RPS20",1.8,27.89,15.47,3.95,0,"up","yes"]
["chr2",88846694,89100361,"IGKV1-16",3.87,56.65,14.66,3.87,0,"up","yes"]
["chr5",82273320,82278419,"RPS23",2.37,34.28,14.46,3.85,0,"up","yes"]
["chr17",48070052,48101198,"CBX1",0.29,4.56,15.53,3.96,0,"up","yes"]
["chr5",169761307,170083377,"DOCK2",0.64,9.28,14.41,3.85,0,"up","yes"]
["chr1",153543613,153545063,"S100A4",1.55,23.18,14.94,3.9,0,"up","yes"]
["chr17",47826895,47831523,"MRPL10",2.08,29.9,14.4,3.85,0,"up","yes"]
["chr14",50725833,50831121,"NIN",0.16,2.3,14.76,3.88,0,"up","yes"]
["chr14",50725840,50831121,"NIN",0.26,3.56,13.97,3.8,0,"up","yes"]
["chr8",22059348,22082518,"DMTN",1.39,18.96,13.63,3.77,0,"up","yes"]
["chr16",57249039,57284661,"PLLP",0.16,2.3,13.95,3.8,0,"up","yes"]
["chr5",179614178,179623710,"HNRNPH1",1.91,25.43,13.28,3.73,0,"up","yes"]
["chr2",89085177,89085787,"IGKV3-15",1.5,21.51,14.33,3.84,0,"up","yes"]
["chr1",25244072,25247446,"RSRP1",0.4,5.58,14.02,3.81,0,"up","yes"]
["chr3",52547990,52679713,"PBRM1",0.15,2.05,14.04,3.81,0,"up","yes"]
["chr2",47818417,47905568,"FBXO11",0.48,6.67,13.78,3.78,0,"up","yes"]
["chr1",206905019,206921867,"FCMR",0.95,12.88,13.6,3.77,0,"up","yes"]
["chr17",63805508,63819209,"DDX42",0.55,7.19,13.17,3.72,0,"up","yes"]
["chr4",6640091,6642729,"MRFAP1",0.66,8.9,13.39,3.74,0,"up","yes"]
["chr16",4461680,4474895,"NMRAL1",0.59,8.05,13.67,3.77,0,"up","yes"]
["chr5",179614179,179623721,"HNRNPH1",2.13,27.24,12.8,3.68,0,"up","yes"]
["chr8",25390866,25412910,"DOCK5",0.48,6.32,13.11,3.71,0,"up","yes"]
["chr6",144539299,144852732,"UTRN",0.66,8.4,12.79,3.68,0,"up","yes"]
["chr3",9429950,9476478,"SETD5",0.21,2.83,13.21,3.72,0,"up","yes"]
["chr8",56073042,56074506,"RPS20",1.59,20.74,13.07,3.71,0,"up","yes"]
["chr7",135926761,135977316,"MTPN",1.21,15.09,12.5,3.64,0,"up","yes"]
["chr3",9783128,9792736,"TADA3",0.57,7.39,12.92,3.69,0,"up","yes"]
["chr1",154582067,154627964,"ADAR",0.84,10.45,12.45,3.64,0,"up","yes"]
["chr7",92070138,92109061,"AKAP9",0.14,1.85,13.22,3.72,0,"up","yes"]
["chr15",65578782,65611245,"INTS14",0.29,3.84,13.32,3.74,0,"up","yes"]
["chr15",65661815,65761437,"DENND4A",0.11,1.5,13.27,3.73,0,"up","yes"]
["chr1",29147853,29173494,"SRSF4",0.09,1.18,13.25,3.73,0,"up","yes"]
["chr12",120534365,120577594,"RNF10",0.7,8.74,12.43,3.64,0,"up","yes"]
["chr15",64841883,64868000,"PLEKHO2",0.37,4.64,12.63,3.66,0,"up","yes"]
["chr5",446149,467285,"EXOC3",0.53,6.61,12.57,3.65,0,"up","yes"]
["chr20",34742338,34782314,"NCOA6",0.67,8.28,12.28,3.62,0,"up","yes"]
["chr9",112218604,112333620,"PTBP3",0.39,4.7,12.16,3.6,0,"up","yes"]
["chr19",4675764,4714220,"DPP9",0.29,3.62,12.46,3.64,0,"up","yes"]
["chrX",147911951,147951112,"FMR1",0.23,2.91,12.65,3.66,0,"up","yes"]
["chr11",128458761,128522310,"ETS1",0.46,5.58,12.12,3.6,0,"up","yes"]
["chr16",31117664,31131389,"KAT8",0.85,10.31,12.15,3.6,0,"up","yes"]
["chr1",155689058,155739010,"DAP3",0.47,5.71,12.21,3.61,0,"up","yes"]
["chr18",58671386,58754477,"MALT1",0.24,2.81,11.73,3.55,0,"up","yes"]
["chr13",32516894,32525579,"N4BP2L2",0.15,1.82,12.16,3.6,0,"up","yes"]
["chr16",57040650,57083520,"NLRC5",0.64,7.43,11.6,3.54,0,"up","yes"]
["chr3",33798571,33869707,"PDCD6IP",0.41,4.7,11.51,3.53,0,"up","yes"]
["chr12",130872070,130876281,"RAN",1.27,14.78,11.62,3.54,0,"up","yes"]
["chr2",74361156,74391867,"DCTN1",0.28,3.37,11.85,3.57,0,"up","yes"]
["chr9",129887187,130043194,"FNBP1",0.47,5.39,11.49,3.52,0,"up","yes"]
["chr6",53001279,53061770,"ICK",0.18,2.16,11.73,3.55,0,"up","yes"]
["chr9",129835470,129881828,"USP20",0.23,2.7,11.79,3.56,0,"up","yes"]
["chr17",78107401,78128771,"TMC6",1,11.17,11.18,3.48,0,"up","yes"]
["chr12",132136594,132144335,"DDX51",0.16,1.91,11.98,3.58,0,"up","yes"]
["chr12",54230940,54280102,"CBX5",0.4,4.44,11.06,3.47,0,"up","yes"]
["chr14",22547506,22552154,"TRAC",0.81,9.46,11.7,3.55,0,"up","yes"]
["chr7",142785922,142793374,"AC245427.1",3.19,34.88,10.92,3.45,0,"up","yes"]
["chr1",244853752,244864494,"HNRNPU",0.45,5.09,11.19,3.48,0,"up","yes"]
["chr3",9433302,9476459,"SETD5",0.25,2.77,11.11,3.47,0,"up","yes"]
["chr17",81245000,81295305,"SLC38A10",0.62,6.62,10.75,3.43,0,"up","yes"]
["chr7",93131033,93148345,"SAMD9L",0.25,2.66,10.86,3.44,0,"up","yes"]
["chr6",30676391,30687895,"PPP1R18",0.54,5.76,10.6,3.41,0,"up","yes"]
["chr12",49185621,49189066,"TUBA1A",4.58,48.01,10.47,3.39,0,"up","yes"]
["chrX",110003115,110177788,"TMEM164",0.48,5.07,10.57,3.4,0,"up","yes"]
["chr3",17159004,17742575,"TBC1D5",0.15,1.72,11.31,3.5,0,"up","yes"]
["chrX",45059247,45111707,"KDM6A",0.57,6.08,10.59,3.4,0,"up","yes"]
["chr6",3153669,3157526,"TUBB2A",1.48,15.6,10.56,3.4,0,"up","yes"]
["chr1",92474762,92483954,"GFI1",0.27,3.02,11.01,3.46,0,"up","yes"]
["chr15",34233259,34336844,"SLC12A6",0.34,3.67,10.69,3.42,0,"up","yes"]
["chr22",50525756,50530032,"TYMP",0.82,8.75,10.71,3.42,0,"up","yes"]
["chr15",24954948,24978539,"SNRPN",0.55,6,10.86,3.44,0,"up","yes"]
["chr3",177022926,177098493,"TBL1XR1",0.24,2.64,10.87,3.44,0,"up","yes"]
["chr12",109929804,109996304,"GIT2",0.58,6.05,10.36,3.37,0,"up","yes"]
["chr5",75511756,75601144,"POLK",0.14,1.52,10.81,3.43,0,"up","yes"]
["chr6",31463182,31465704,"HCP5",3.07,31.27,10.18,3.35,0,"up","yes"]
["chr3",25615473,25664907,"TOP2B",0.57,5.87,10.26,3.36,0,"up","yes"]
["chr20",34519419,34540958,"DYNLRB1",2.13,22.21,10.43,3.38,0,"up","yes"]
["chr3",179017223,179072279,"ZMAT3",0.15,1.53,10.47,3.39,0,"up","yes"]
["chr8",56073054,56074510,"RPS20",1.93,20.31,10.53,3.4,0,"up","yes"]
["chr9",15485903,15510289,"PSIP1",1.41,14.63,10.4,3.38,0,"up","yes"]
["chr19",45818913,45863130,"SYMPK",0.28,2.85,10.19,3.35,0,"up","yes"]
["chr2",126656184,126696664,"GYPC",20.01,195.32,9.76,3.29,0,"up","yes"]
["chr9",137007242,137018219,"ABCA2",0.45,4.46,9.9,3.31,0,"up","yes"]
["chr13",97222355,97394120,"MBNL2",0.16,1.62,10.42,3.38,0,"up","yes"]
["chr14",54474485,54489196,"GMFB",0.21,2.14,10.31,3.37,0,"up","yes"]
["chrMT",956,12061,"MT-TN",11.43,108.6,9.51,3.25,0,"up","yes"]
["chr6",43037617,43053699,"CUL7",0.14,1.41,10.27,3.36,0,"up","yes"]
["chr20",37517417,37527931,"BLCAP",1.38,13.28,9.59,3.26,0,"up","yes"]
["chr3",158801865,158829719,"MFSD1",0.41,4.04,9.97,3.32,0,"up","yes"]
["chr1",243501763,243850128,"AKT3",0.15,1.48,10.06,3.33,0,"up","yes"]
["chr12",6772512,6778455,"LAG3",0.42,4.11,9.83,3.3,0,"up","yes"]
["chr12",123973212,124015426,"ZNF664",0.63,5.96,9.47,3.24,0,"up","yes"]
["chr20",35701821,35742250,"RBM39",0.42,4.02,9.49,3.25,0,"up","yes"]
["chr1",228393673,228405904,"TRIM11",0.18,1.77,9.84,3.3,0,"up","yes"]
["chr4",70655544,70666631,"JCHAIN",1.56,14.81,9.48,3.24,0,"up","yes"]
["chr3",58332948,58426019,"PXK",0.28,2.77,9.8,3.29,0,"up","yes"]
["chr13",114234977,114272675,"CDC16",0.4,3.9,9.86,3.3,0,"up","yes"]
["chr1",161524540,161526910,"HSPA6",0.45,4.37,9.69,3.28,0,"up","yes"]
["chr3",51993629,51995844,"RPL29",1.02,10.13,9.94,3.31,0,"up","yes"]
["chr3",186783305,186789967,"EIF4A2",0.82,7.65,9.29,3.22,0,"up","yes"]
["chrX",24149745,24216089,"ZFX",0.38,3.5,9.22,3.2,0,"up","yes"]
["chr2",74483086,74493987,"TTC31",0.65,6.04,9.34,3.22,0,"up","yes"]
["chr9",128179214,128190834,"CIZ1",0.71,6.98,9.86,3.3,0,"up","yes"]
["chr12",54498784,54542963,"NCKAP1L",2.34,21.21,9.06,3.18,0,"up","yes"]
["chr5",139293963,139330437,"MATR3",1.18,10.69,9.05,3.18,0,"up","yes"]
["chr11",67435510,67438067,"PTPRCAP",3.28,29.67,9.05,3.18,0,"up","yes"]
["chr22",22822658,22823289,"IGLV2-8",1.54,14.66,9.52,3.25,0,"up","yes"]
["chr8",42271389,42332455,"IKBKB",0.24,2.22,9.41,3.23,0,"up","yes"]
["chr19",49085423,49108479,"SNRNP70",1.26,11.51,9.16,3.2,0,"up","yes"]
["chr5",139387568,139389914,"MZB1",1.07,10.2,9.51,3.25,0,"up","yes"]
["chr16",15594386,15643166,"MARF1",1.32,11.71,8.9,3.15,0,"up","yes"]
["chr11",3826978,3840983,"RHOG",7.08,62.49,8.83,3.14,0,"up","yes"]
["chr2",174532449,174634903,"WIPF1",1.04,9.31,8.94,3.16,0,"up","yes"]
["chr4",122239965,122276189,"KIAA1109",0.29,2.63,9.12,3.19,0,"up","yes"]
["chr1",16562319,16613487,"NBPF1",0.17,1.57,9.2,3.2,0,"up","yes"]
["chr8",22056820,22082525,"DMTN",3.26,28.29,8.69,3.12,0,"up","yes"]
["chr22",50245183,50251385,"HDAC10",0.43,3.92,9.11,3.19,0,"up","yes"]
["chr17",68413554,68532770,"PRKAR1A",0.38,3.43,8.95,3.16,0,"up","yes"]
["chr12",122980060,122982913,"ARL6IP4",0.66,6,9.12,3.19,0,"up","yes"]
["chr6",41546426,41602384,"FOXP4",0.12,1.13,9.17,3.2,0,"up","yes"]
["chrX",77506905,77596875,"ATRX",0.13,1.15,9.06,3.18,0,"up","yes"]
["chr14",105741338,105743071,"IGHG1",8.59,73.05,8.51,3.09,0,"up","yes"]
["chr16",30352847,30354934,"CD2BP2",0.5,4.63,9.16,3.2,0,"up","yes"]
["chr1",39565106,39575781,"PABPC4",1.74,15.14,8.7,3.12,0,"up","yes"]
["chr1",15526813,15571731,"DNAJC16",0.17,1.56,9,3.17,0,"up","yes"]
["chr19",7395113,7472477,"ARHGEF18",0.32,2.81,8.76,3.13,0,"up","yes"]
["chr17",16031404,16194613,"NCOR1",0.2,1.72,8.73,3.13,0,"up","yes"]
["chr7",107207848,107564261,"COG5",0.33,2.91,8.73,3.13,0,"up","yes"]
["chr22",38290692,38317408,"CSNK1E",0.33,2.96,9.02,3.17,0,"up","yes"]
["chr8",56073054,56074510,"RPS20",13.39,111.83,8.35,3.06,0,"up","yes"]
["chr14",105643068,105644790,"IGHG2",10.52,87.1,8.28,3.05,0,"up","yes"]
["chr14",104689637,104719603,"INF2",0.67,5.67,8.41,3.07,0,"up","yes"]
["chr14",92939862,93115279,"ITPK1",0.34,2.99,8.71,3.12,0,"up","yes"]
["chr12",98645300,98735433,"APAF1",0.21,1.76,8.52,3.09,0,"up","yes"]
["chr22",44677057,44737680,"PRR5",0.57,5.02,8.73,3.13,0,"up","yes"]
["chr2",201258036,201287711,"CASP8",0.28,2.44,8.69,3.12,0,"up","yes"]
["chr1",150811961,150876609,"ARNT",1.32,10.98,8.31,3.06,0,"up","yes"]
["chr14",105707118,105708665,"IGHA1",35.67,289.4,8.11,3.02,0,"up","yes"]
["chr14",96502558,96565428,"PAPOLA",0.77,6.39,8.3,3.05,0,"up","yes"]
["chr3",12836060,12841529,"RPL32",4.01,32.64,8.13,3.02,0,"up","yes"]
["chr20",35650326,35664900,"RBM12",0.39,3.28,8.32,3.06,0,"up","yes"]
["chr1",8354093,8423666,"RERE",0.98,7.98,8.15,3.03,0,"up","yes"]
["chr12",123295905,123364828,"SBNO1",0.24,2.02,8.46,3.08,0,"up","yes"]
["chr2",219279267,219286900,"DNAJB2",0.56,4.66,8.25,3.05,0,"up","yes"]
["chr2",88947301,88947957,"IGKV1-5",2.56,21.29,8.33,3.06,0,"up","yes"]
["chr14",55271303,55353609,"FBXO34",0.38,3.18,8.32,3.06,0,"up","yes"]
["chr12",51281038,51324154,"BIN2",0.88,7.2,8.19,3.03,0,"up","yes"]
["chr2",88857161,88857683,"IGKC",4.61,37.15,8.06,3.01,0,"up","yes"]
["chr6",31723373,31726714,"MPIG6B",1.49,11.89,7.97,3,0,"up","yes"]
["chr5",134758804,134829296,"DDX46",1.27,10.06,7.9,2.98,0,"up","yes"]
["chr22",23638487,23717321,"GUSBP11",0.27,2.29,8.41,3.07,0,"up","yes"]
["chrX",153802166,153830490,"PDZD4",0.29,2.42,8.29,3.05,0,"up","yes"]
["chr17",17812073,17836987,"SREBF1",0.17,1.46,8.4,3.07,0,"up","yes"]
["chr1",226063977,226072001,"H3F3A",0.67,5.53,8.26,3.05,0,"up","yes"]
["chr5",173888280,173961976,"CPEB4",0.15,1.22,8.01,3,0,"up","yes"]
["chr12",10304446,10329600,"KLRD1",0.21,1.62,7.82,2.97,0,"up","yes"]
["chr20",51386957,51542719,"NFATC2",0.91,6.99,7.67,2.94,0,"up","yes"]
["chr20",50190734,50192689,"CEBPB",2.24,17.17,7.66,2.94,0,"up","yes"]
["chr9",131576770,131676821,"RAPGEF1",0.33,2.56,7.75,2.95,0,"up","yes"]
["chr17",50962174,51120865,"SPAG9",0.38,2.94,7.7,2.95,0,"up","yes"]
["chr14",50725827,50830479,"NIN",0.16,1.32,8.18,3.03,0,"up","yes"]
["chr7",5190196,5231524,"WIPI2",0.78,6.06,7.79,2.96,0,"up","yes"]
["chr15",68054179,68198685,"PIAS1",0.22,1.7,7.73,2.95,0,"up","yes"]
["chr14",52730180,52774941,"STYX",0.24,1.88,8,3,0,"up","yes"]
["chr17",48831035,48863174,"CALCOCO2",1.01,7.86,7.77,2.96,0,"up","yes"]
["chr2",73829020,73867172,"STAMBP",0.26,1.99,7.7,2.94,0,"up","yes"]
["chr11",64764606,64778786,"SF1",0.44,3.43,7.79,2.96,0,"up","yes"]
["chr2",88857161,89100347,"IGKV1-16",1.21,9.48,7.81,2.96,0,"up","yes"]
["chr7",75915164,75986855,"POR",0.47,3.61,7.75,2.95,0,"up","yes"]
["chr7",45027026,45076451,"CCM2",0.66,5.07,7.64,2.93,0,"up","yes"]
["chr3",121663203,121749740,"GOLGB1",0.45,3.36,7.44,2.9,0,"up","yes"]
["chr15",90529925,90645345,"CRTC3",1.31,9.66,7.39,2.89,0,"up","yes"]
["chr10",102133030,102150325,"PPRC1",0.7,5.18,7.41,2.89,0,"up","yes"]
["chr9",128552590,128633658,"SPTAN1",0.98,7.18,7.33,2.87,0,"up","yes"]
["chr1",1702736,1737688,"AL031282.2",0.52,3.85,7.39,2.89,0,"up","yes"]
["chr8",22056878,22082525,"DMTN",3.7,26.81,7.24,2.86,0,"up","yes"]
["chr1",154156359,154183147,"TPM3",1.8,13.07,7.26,2.86,0,"up","yes"]
["chr2",89862482,89862981,"IGKV1D-39",2.67,20.27,7.6,2.93,0,"up","yes"]
["chr5",179614179,179618899,"HNRNPH1",0.41,3.09,7.53,2.91,0,"up","yes"]
["chr16",87959871,88077315,"BANP",0.47,3.5,7.53,2.91,0,"up","yes"]
["chr16",68084751,68226471,"NFATC3",2.83,20.4,7.21,2.85,0,"up","yes"]
["chr12",57472255,57479850,"ARHGAP9",0.43,3.23,7.51,2.91,0,"up","yes"]
["chr15",41517179,41544245,"RPAP1",0.13,1.03,7.64,2.93,0,"up","yes"]
["chrX",154379242,154381523,"EMD",0.64,4.81,7.54,2.92,0,"up","yes"]
["chr3",160399668,160433990,"SMC4",0.21,1.6,7.55,2.92,0,"up","yes"]
["chr16",22297455,22329091,"POLR3E",0.24,1.79,7.5,2.91,0,"up","yes"]
["chrX",134769566,134797134,"FAM122B",0.24,1.76,7.48,2.9,0,"up","yes"]
["chr1",150810859,150876579,"ARNT",0.19,1.45,7.64,2.93,0,"up","yes"]
["chr11",117205074,117226876,"PCSK7",0.45,3.23,7.24,2.86,0,"up","yes"]
["chr8",22605038,22620471,"CCAR2",0.99,7.06,7.14,2.84,0,"up","yes"]
["chr12",113319974,113335143,"SLC8B1",0.51,3.85,7.51,2.91,0,"up","yes"]
["chr16",4425805,4456772,"DNAJA3",0.31,2.38,7.59,2.92,0,"up","yes"]
["chr3",51385409,51389344,"MANF",0.45,3.44,7.62,2.93,0,"up","yes"]
["chr1",161541855,161549898,"FCGR3A",0.7,5.12,7.3,2.87,0,"up","yes"]
["chr11",119067801,119081972,"VPS11",1.82,12.88,7.1,2.83,0,"up","yes"]
["chr8",96231297,96235545,"UQCRB",2.02,14.87,7.35,2.88,0,"up","yes"]
["chr19",49496434,49499689,"RPS11",4.01,28.78,7.17,2.84,0,"up","yes"]
["chr8",41929479,42051987,"KAT6A",0.57,4.02,7.07,2.82,0,"up","yes"]
["chr4",70655541,70666660,"JCHAIN",9.16,64.02,6.99,2.8,0,"up","yes"]
["chr9",122371080,122393178,"PTGS1",3.13,21.89,7,2.81,0,"up","yes"]
["chr2",46901874,46915868,"MCFD2",0.7,4.99,7.08,2.82,0,"up","yes"]
["chr21",46459057,46547205,"DIP2A",0.39,2.88,7.4,2.89,0,"up","yes"]
["chr1",202878957,202889135,"RABIF",0.32,2.38,7.54,2.91,0,"up","yes"]
["chr9",35056870,35072549,"VCP",0.84,5.95,7.08,2.82,0,"up","yes"]
["chr9",137204082,137205638,"TMEM203",1.03,7.39,7.19,2.85,0,"up","yes"]
["chr1",53214099,53220617,"C1orf123",1.55,11.06,7.16,2.84,0,"up","yes"]
["chr15",72340919,72376476,"HEXA",0.8,5.62,6.98,2.8,0,"up","yes"]
["chr1",42683156,42697211,"YBX1",7.23,50.37,6.96,2.8,0,"up","yes"]
["chr16",2223566,2235742,"E4F1",0.71,5.04,7.11,2.83,0,"up","yes"]
["chr18",9546910,9551939,"PPP4R1",0.26,1.96,7.44,2.9,0,"up","yes"]
["chr21",46561285,46569708,"DIP2A",0.24,1.8,7.37,2.88,0,"up","yes"]
["chr6",33303573,33314212,"TAPBP",2.25,15.65,6.94,2.8,0,"up","yes"]
["chr12",49184959,49188899,"TUBA1A",2.2,15.29,6.94,2.79,0,"up","yes"]
["chr1",206904714,206921955,"FCMR",1.71,12.34,7.21,2.85,0,"up","yes"]
["chr14",22766696,22771761,"OXA1L",1.45,10.16,7,2.81,0,"up","yes"]
["chr22",40410290,40636691,"MKL1",0.27,1.92,7.16,2.84,0,"up","yes"]
["chr11",576521,611964,"PHRF1",0.33,2.3,7.06,2.82,0,"up","yes"]
["chr6",152121741,152185495,"SYNE1",1.84,12.61,6.85,2.78,0,"up","yes"]
["chr1",108692341,108701803,"PRPF38B",0.33,2.36,7.18,2.84,0,"up","yes"]
["chr21",45074600,45226560,"ADARB1",0.17,1.24,7.26,2.86,0,"up","yes"]
["chr4",108047778,108167003,"LEF1",0.76,5.32,6.97,2.8,0,"up","yes"]
["chr14",75013764,75051532,"MLH3",0.14,1.04,7.15,2.84,0,"up","yes"]
["chr1",45550783,45570048,"AKR1A1",0.6,4.35,7.26,2.86,0,"up","yes"]
["chr8",108233394,108248698,"EIF3E",1.54,10.95,7.13,2.83,0,"up","yes"]
["chr11",62787403,62790118,"TMEM179B",3.16,22.07,6.98,2.8,0,"up","yes"]
["chr17",17246837,17281191,"COPS3",0.95,6.6,6.97,2.8,0,"up","yes"]
["chrX",72255661,72277300,"RPS4X",29.84,201.37,6.75,2.75,0,"up","yes"]
["chr17",74737232,74747335,"RAB37",0.42,2.99,7.13,2.83,0,"up","yes"]
["chr5",96662352,96774694,"CAST",0.26,1.84,7.12,2.83,0,"up","yes"]
["chr12",49791146,49828425,"NCKAP5L",0.38,2.66,6.92,2.79,0,"up","yes"]
["chr11",46347588,46380367,"DGKZ",0.77,5.28,6.85,2.78,0,"up","yes"]
["chr7",1530714,1543043,"MAFK",0.84,5.77,6.84,2.77,0,"up","yes"]
["chr19",18153158,18178117,"AC007192.1",1.67,11.29,6.74,2.75,0,"up","yes"]
["chr1",77948405,77979092,"FUBP1",0.74,5.13,6.88,2.78,0,"up","yes"]
["chr19",41264417,41306991,"HNRNPUL1",5.46,36.59,6.69,2.74,0,"up","yes"]
["chr16",88645965,88650988,"CYBA",1.58,10.95,6.95,2.8,0,"up","yes"]
["chr8",56073075,56074506,"RPS20",3.8,26.36,6.95,2.8,0,"up","yes"]
["chr1",231332753,231337852,"EXOC8",0.4,2.77,6.84,2.77,0,"up","yes"]
["chr1",203795714,203854999,"ZBED6",0.27,1.84,6.76,2.76,0,"up","yes"]
["chr17",77453993,77499040,"9-Sep",7,46.73,6.68,2.74,0,"up","yes"]
["chr4",17614631,17634105,"MED28",0.55,3.71,6.71,2.75,0,"up","yes"]
["chr5",96662237,96774683,"CAST",0.27,1.89,7.03,2.81,0,"up","yes"]
["chr3",52198132,52214324,"ALAS1",0.43,3.05,7.05,2.82,0,"up","yes"]
["chr22",17638584,17730855,"BCL2L13",0.18,1.26,7.07,2.82,0,"up","yes"]
["chr4",102261666,102345139,"SLC39A8",0.24,1.7,7.11,2.83,0,"up","yes"]
["chr19",45818955,45855710,"SYMPK",0.24,1.64,6.78,2.76,0,"up","yes"]
["chr4",6707701,6709880,"MRFAP1L1",3.89,25.66,6.6,2.72,0,"up","yes"]
["chr15",81299416,81306852,"IL16",4.62,30.21,6.54,2.71,0,"up","yes"]
["chr19",6887566,6940459,"ADGRE1",0.73,4.82,6.65,2.73,0,"up","yes"]
["chr17",16031404,16215457,"NCOR1",0.2,1.34,6.77,2.76,0,"up","yes"]
["chr8",22059206,22082518,"DMTN",3.1,20.28,6.54,2.71,0,"up","yes"]
["chr5",40762770,40798374,"PRKAA1",1.44,9.54,6.6,2.72,0,"up","yes"]
["chr10",96832298,96995959,"LCOR",0.18,1.18,6.62,2.73,0,"up","yes"]
["chrX",48914104,48914914,"PIM2",1.3,9.09,6.98,2.8,0,"up","yes"]
["chr10",97737123,97760907,"ZFYVE27",0.22,1.53,6.93,2.79,0,"up","yes"]
["chr12",120196702,120201107,"RPLP0",4.77,31.11,6.52,2.7,0,"up","yes"]
["chr15",88621296,88632282,"AEN",0.32,2.21,6.84,2.77,0,"up","yes"]
["chr10",45454585,45535394,"8-Mar",1.47,9.49,6.45,2.69,0,"up","yes"]
["chr15",24954935,24978583,"SNRPN",1.92,12.6,6.57,2.72,0,"up","yes"]
["chr16",11547722,11587563,"LITAF",3.85,24.79,6.43,2.68,0,"up","yes"]
["chr17",74609887,74623738,"CD300E",2.41,15.46,6.42,2.68,0,"up","yes"]
["chr18",46089599,46104227,"ATP5A1",3.71,24.16,6.51,2.7,0,"up","yes"]
["chr11",4598672,4608259,"TRIM68",0.33,2.24,6.68,2.74,0,"up","yes"]
["chr6",29887950,29945882,"HLA-A",18.98,120.56,6.35,2.67,0,"up","yes"]
["chr19",2272524,2273331,"OAZ1",5.2,33.57,6.45,2.69,0,"up","yes"]
["chr7",139375204,139423201,"LUC7L2",0.47,3.13,6.66,2.74,0,"up","yes"]
["chr11",309055,309422,"IFITM2",8.05,52.14,6.47,2.69,0,"up","yes"]
["chr20",1443735,1466824,"NSFL1C",0.9,5.97,6.63,2.73,0,"up","yes"]
["chr16",67645247,67657518,"CARMIL2",0.57,3.69,6.45,2.69,0,"up","yes"]
["chr2",74555132,74557513,"DOK1",0.39,2.7,6.82,2.77,0,"up","yes"]
["chr14",105707111,105863978,"IGHA1",86.27,542.01,6.28,2.65,0,"up","yes"]
["chr4",173331701,173334391,"HMGB2",2.88,18.34,6.37,2.67,0,"up","yes"]
["chr16",28974804,28990775,"AC109460.3",0.95,6.05,6.34,2.66,0,"up","yes"]
["chr17",35473689,35487857,"SLFN12L",0.21,1.45,6.82,2.77,0,"up","yes"]
["chr9",134902122,134905861,"FCN1",0.24,1.58,6.72,2.75,0,"up","yes"]
["chr11",67440791,67443472,"CORO1B",0.75,5.03,6.69,2.74,0,"up","yes"]
["chr1",26282284,26306645,"UBXN11",0.52,3.46,6.68,2.74,0,"up","yes"]
["chr11",60913874,60923443,"TMEM109",3.3,20.65,6.26,2.65,0,"up","yes"]
["chr16",88570403,88631757,"ZC3H18",0.8,5.05,6.34,2.66,0,"up","yes"]
["chr17",40062899,40092627,"THRA",0.6,3.8,6.34,2.66,0,"up","yes"]
["chr1",156594487,156601483,"GPATCH4",0.88,5.57,6.37,2.67,0,"up","yes"]
["chr11",118401610,118409577,"ATP5L",0.9,5.87,6.55,2.71,0,"up","yes"]
["chr20",46684365,46689779,"TP53RK",0.58,3.64,6.31,2.66,0,"up","yes"]
["chr12",105177110,105233154,"APPL2",0.43,2.89,6.66,2.74,0,"up","yes"]
["chr7",5190273,5231470,"WIPI2",0.8,5.02,6.31,2.66,0,"up","yes"]
["chr14",74056850,74084493,"ALDH6A1",0.17,1.12,6.46,2.69,0,"up","yes"]
["chr2",96266390,96272173,"CIAO1",0.95,5.91,6.23,2.64,0,"up","yes"]
["chr18",5289019,5296040,"ZBTB14",0.67,4.21,6.24,2.64,0,"up","yes"]
["chr16",28987566,28990454,"LAT",0.3,2.02,6.64,2.73,0,"up","yes"]
["chr11",105025508,105035149,"CASP1",0.86,5.42,6.28,2.65,0,"up","yes"]
["chr17",45263121,45317040,"MAP3K14",0.76,4.69,6.17,2.63,0,"up","yes"]
["chr7",5622695,5761138,"RNF216",0.27,1.75,6.48,2.7,0,"up","yes"]
["chr7",43875915,43907069,"URGCP",0.34,2.14,6.32,2.66,0,"up","yes"]
["chr12",56041853,56044675,"RPS26",8.42,51.14,6.07,2.6,0,"up","yes"]
["chr12",752576,909436,"WNK1",3.35,20.21,6.04,2.59,0,"up","yes"]
["chr17",42020051,42025058,"NKIRAS2",0.69,4.33,6.3,2.66,0,"up","yes"]
["chr1",27344873,27353930,"SYTL1",0.46,2.94,6.37,2.67,0,"up","yes"]
["chr10",180013,249261,"ZMYND11",0.7,4.39,6.25,2.64,0,"up","yes"]
["chrX",136216811,136251579,"MAP7D3",0.26,1.62,6.28,2.65,0,"up","yes"]
["chr16",15594387,15643024,"MARF1",0.6,3.64,6.04,2.59,0,"up","yes"]
["chr17",35809455,35847242,"TAF15",0.96,5.89,6.12,2.61,0,"up","yes"]
["chr1",24643308,24671595,"SRRM1",2.34,14.07,6.01,2.59,0,"up","yes"]
["chr17",35010042,35089264,"AC004223.3",0.9,5.5,6.08,2.61,0,"up","yes"]
["chr3",112120841,112133305,"GCSAM",0.48,2.96,6.16,2.62,0,"up","yes"]
["chr15",31345319,31377698,"KLF13",0.43,2.62,6.11,2.61,0,"up","yes"]
["chr16",89707134,89719369,"VPS9D1",0.4,2.51,6.24,2.64,0,"up","yes"]
["chrX",48458693,48460854,"SLC38A5",7.46,44.55,5.98,2.58,0,"up","yes"]
["chr9",132909811,132944595,"TSC1",0.43,2.66,6.24,2.64,0,"up","yes"]
["chr14",75661268,75886867,"TTLL5",0.27,1.66,6.22,2.64,0,"up","yes"]
["chr10",101785831,101818435,"MGEA5",2.21,13.15,5.94,2.57,0,"up","yes"]
["chr1",247857199,247878205,"TRIM58",3.81,22.59,5.92,2.57,0,"up","yes"]
["chrX",48458537,48470177,"SLC38A5",8.76,51.75,5.91,2.56,0,"up","yes"]
["chr19",1426349,1435684,"DAZAP1",0.33,2.06,6.16,2.62,0,"up","yes"]
["chr9",124869205,124877717,"ARPC5L",1.84,11.04,6.01,2.59,0,"up","yes"]
["chr17",27631148,27649433,"LGALS9",0.79,4.87,6.15,2.62,0,"up","yes"]
["chr20",35302566,35412141,"UQCC1",0.42,2.62,6.2,2.63,0,"up","yes"]
["chr1",43445252,43452650,"SZT2",0.19,1.19,6.28,2.65,0,"up","yes"]
["chr19",45620812,45639401,"EML2",0.64,3.97,6.19,2.63,0,"up","yes"]
["chr9",128179051,128191488,"CIZ1",0.89,5.58,6.28,2.65,0,"up","yes"]
["chr6",31615211,31617027,"AIF1",0.95,6.03,6.36,2.67,0,"up","yes"]
["chr12",55829608,55836244,"TMEM198B",0.28,1.76,6.2,2.63,0,"up","yes"]
["chr1",34986165,35031711,"ZMYM6",0.25,1.5,6.03,2.59,0,"up","yes"]
["chr8",143580620,143587564,"EEF1D",1.29,7.83,6.05,2.6,0,"up","yes"]
["chr9",77177445,77421541,"VPS13A",0.19,1.12,5.93,2.57,0,"up","yes"]
["chr3",197044331,197297204,"DLG1",0.78,4.63,5.95,2.57,0,"up","yes"]
["chr14",94110747,94116696,"IFI27",4.1,24.39,5.95,2.57,0,"up","yes"]
["chr16",18782956,18790383,"RPS15A",87.56,506.6,5.79,2.53,0,"up","yes"]
["chr2",32165864,32224379,"SLC30A6",0.35,2.07,5.99,2.58,0,"up","yes"]
["chr7",142626649,142627399,"TRBV20-1",2.37,14.45,6.11,2.61,0,"up","yes"]
["chr1",726126,740555,"AL669831.1",0.64,3.75,5.89,2.56,0,"up","yes"]
["chr7",150685700,150693641,"GIMAP2",2.5,14.64,5.86,2.55,0,"up","yes"]
["chr22",22906342,22906803,"IGLC3",9.38,54.83,5.85,2.55,0,"up","yes"]
["chr3",141387812,141449792,"ZBTB38",0.59,3.45,5.83,2.54,0,"up","yes"]
["chr19",10654304,10689847,"ILF3",0.36,2.13,5.98,2.58,0,"up","yes"]
["chr19",41431318,41439910,"DMAC2",0.98,5.89,6,2.59,0,"up","yes"]
["chr17",76734123,76737308,"SRSF2",0.73,4.47,6.09,2.61,0,"up","yes"]
["chr17",41867574,41919022,"ACLY",1.79,10.36,5.79,2.53,0,"up","yes"]
["chr14",105854220,105856218,"IGHM",5.95,34.31,5.77,2.53,0,"up","yes"]
["chr17",76395358,76453141,"UBE2O",0.2,1.24,6.21,2.63,0,"up","yes"]
["chr10",125836340,125881315,"DHX32",0.22,1.39,6.22,2.64,0,"up","yes"]
["chr11",72097348,72103236,"LAMTOR1",0.65,3.95,6.1,2.61,0,"up","yes"]
["chr10",128096659,128126385,"MKI67",0.32,1.88,5.79,2.53,0,"up","yes"]
["chr10",110871795,110900005,"PDCD4",0.48,2.81,5.88,2.56,0,"up","yes"]
["chr11",64230758,64234281,"DNAJC4",1.89,11.08,5.87,2.55,0,"up","yes"]
["chr5",139387569,139389883,"MZB1",0.48,2.96,6.12,2.61,0,"up","yes"]
["chr17",50719599,50751617,"LUC7L3",0.91,5.35,5.87,2.55,0,"up","yes"]
["chr9",19230435,19372858,"DENND4C",0.61,3.53,5.76,2.53,0,"up","yes"]
["chr2",130356007,130375409,"PTPN18",1.53,8.73,5.73,2.52,0,"up","yes"]
["chr1",192106200,192139432,".",1.72,10.5,6.1,2.61,0,"up","yes"]
["chr6",18225631,18264147,"DEK",2.48,14.34,5.79,2.53,0,"up","yes"]
["chr19",1611168,1650745,"TCF3",0.8,4.65,5.79,2.53,0,"up","yes"]
["chr15",50241947,50266026,"HDC",0.31,1.85,6.04,2.59,0,"up","yes"]
["chr5",150357639,150400307,"TCOF1",0.63,3.63,5.76,2.52,0,"up","yes"]
["chr9",72355833,72364626,"ZFAND5",0.94,5.61,5.96,2.58,0,"up","yes"]
["chr18",50282349,50287115,"CXXC1",0.45,2.7,5.94,2.57,0,"up","yes"]
["chr22",50217689,50244992,"TUBGCP6",0.74,4.24,5.7,2.51,0,"up","yes"]
["chr4",15604072,15681679,"FBXL5",0.47,2.73,5.77,2.53,0,"up","yes"]
["chr8",143579729,143597400,"EEF1D",1.36,7.95,5.86,2.55,0,"up","yes"]
["chr14",21399606,21409890,"CHD8",0.4,2.39,5.96,2.57,0,"up","yes"]
["chr18",49488453,49492482,"RPL17",1.2,7.16,5.94,2.57,0,"up","yes"]
["chr17",4715589,4721138,"ARRB2",6,33.67,5.61,2.49,0,"up","yes"]
["chr1",223758226,223776018,"CAPN2",0.32,1.87,5.9,2.56,0,"up","yes"]
["chr11",118406127,118409610,"ATP5L",0.51,3.06,5.98,2.58,0,"up","yes"]
["chr4",70657269,70681817,"JCHAIN",3.14,18.64,5.94,2.57,0,"up","yes"]
["chrX",71533025,71575836,"OGT",1.12,6.25,5.59,2.48,0.01,"up","yes"]
["chr20",35953617,35954626,"SCAND1",1.48,8.56,5.8,2.54,0.01,"up","yes"]
["chr10",68332122,68342272,"HNRNPH3",2.72,15.3,5.63,2.49,0.01,"up","yes"]
["chr7",45027634,45076469,"CCM2",1.15,6.57,5.7,2.51,0.01,"up","yes"]
["chr8",22059223,22082524,"DMTN",2.8,15.59,5.57,2.48,0.01,"up","yes"]
["chr1",202203736,202319781,"LGR6",0.29,1.72,5.87,2.55,0.01,"up","yes"]
["chr1",27611416,27635239,"FGR",4.1,22.71,5.54,2.47,0.01,"up","yes"]
["chr17",28546708,28551802,"UNC119",0.27,1.54,5.8,2.54,0.01,"up","yes"]
["chr17",4710699,4721496,"ARRB2",0.95,5.5,5.76,2.53,0.01,"up","yes"]
["chr6",33250538,33271881,"VPS52",1.1,6.2,5.62,2.49,0.01,"up","yes"]
["chr2",27130756,27134675,"PREB",2.1,11.69,5.57,2.48,0.01,"up","yes"]
["chr12",122980189,122982909,"ARL6IP4",0.97,5.59,5.75,2.52,0.01,"up","yes"]
["chr12",51281282,51324668,"BIN2",0.58,3.36,5.76,2.53,0.01,"up","yes"]
["chr6",33420255,33451842,"SYNGAP1",0.45,2.54,5.64,2.5,0.01,"up","yes"]
["chr16",28155242,28211910,"XPO6",3.03,16.67,5.5,2.46,0.01,"up","yes"]
["chr17",7389730,7394843,"PLSCR3",0.63,3.59,5.67,2.5,0.01,"up","yes"]
["chr22",37746319,37776464,"TRIOBP",1.15,6.36,5.51,2.46,0.01,"up","yes"]
["chr12",121626550,121642677,"ORAI1",3.06,16.77,5.49,2.46,0.01,"up","yes"]
["chr11",64784914,64803241,"MAP4K2",0.55,3.01,5.5,2.46,0.01,"up","yes"]
["chr1",150623281,150629577,"ENSA",1.25,6.91,5.52,2.46,0.01,"up","yes"]
["chr16",784974,787981,"RPUSD1",0.37,2.16,5.78,2.53,0.01,"up","yes"]
["chr6",73517515,73521588,"EEF1A1",311.29,1684.2,5.41,2.44,0.01,"up","yes"]
["chr22",39014363,39033276,"AL022318.4",0.44,2.54,5.73,2.52,0.01,"up","yes"]
["chr8",96231063,96233915,"UQCRB",1.13,6.41,5.67,2.5,0.01,"up","yes"]
["chr1",3489926,3611495,"MEGF6",0.2,1.13,5.69,2.51,0.01,"up","yes"]
["chr16",70299224,70372582,"AC012184.2",0.54,3.07,5.67,2.5,0.01,"up","yes"]
["chr20",23079349,23086340,"CD93",3.13,16.8,5.37,2.42,0.01,"up","yes"]
["chr19",53867883,53876428,"MYADM",0.35,1.98,5.64,2.49,0.01,"up","yes"]
["chr4",82818662,82891178,"SEC31A",0.22,1.23,5.7,2.51,0.01,"up","yes"]
["chr14",102139924,102210470,"WDR20",0.62,3.44,5.59,2.48,0.01,"up","yes"]
["chr18",35654560,35711834,"GALNT1",1.1,5.96,5.4,2.43,0.01,"up","yes"]
["chr1",70205698,70250841,"SRSF11",3.93,21.11,5.37,2.43,0.01,"up","yes"]
["chr17",43171214,43210521,"NBR1",3.99,21.26,5.33,2.42,0.01,"up","yes"]
["chr14",95534593,95544718,"GLRX5",5.2,27.84,5.35,2.42,0.01,"up","yes"]
["chr19",14091697,14108390,"PRKACA",0.24,1.38,5.7,2.51,0.01,"up","yes"]
["chr8",8317737,8386498,"PRAG1",0.69,3.71,5.38,2.43,0.01,"up","yes"]
["chr5",149358007,149369653,"PCYOX1L",0.44,2.43,5.56,2.47,0.01,"up","yes"]
["chr21",33543064,33560667,"SON",0.82,4.36,5.32,2.41,0.01,"up","yes"]
["chr12",51281038,51324154,"BIN2",9.59,50.55,5.27,2.4,0.01,"up","yes"]
["chr14",51877592,51969800,"GNG2",0.57,3.08,5.42,2.44,0.01,"up","yes"]
["chr5",150000046,150053142,"HMGXB3",0.69,3.7,5.33,2.41,0.01,"up","yes"]
["chr19",10512742,10517450,"S1PR5",2.27,12.03,5.3,2.41,0.01,"up","yes"]
["chr3",49007608,49015347,"WDR6",0.59,3.17,5.38,2.43,0.01,"up","yes"]
["chr16",69776189,69941739,"WWP2",2.75,14.42,5.24,2.39,0.01,"up","yes"]
["chr16",2520365,2531422,"AMDHD2",0.27,1.49,5.56,2.48,0.01,"up","yes"]
["chr1",161541763,161550028,"FCGR3A",2.32,12.26,5.28,2.4,0.01,"up","yes"]
["chr10",110225993,110286506,"MXI1",13.07,68.09,5.21,2.38,0.01,"up","yes"]
["chr20",23626706,23637945,"CST3",1.04,5.5,5.28,2.4,0.01,"up","yes"]
["chr1",9651732,9729114,"PIK3CD",0.3,1.63,5.38,2.43,0.01,"up","yes"]
["chr12",55760424,55817709,"SARNP",1.59,8.61,5.43,2.44,0.01,"up","yes"]
["chr11",14504913,14520363,"PSMA1",1.47,7.82,5.34,2.42,0.01,"up","yes"]
["chr2",241492674,241508692,"STK25",0.65,3.43,5.29,2.4,0.01,"up","yes"]
["chr1",161541759,161550103,"FCGR3A",2.27,11.86,5.23,2.39,0.01,"up","yes"]
["chr5",55940966,55994792,"IL6ST",0.81,4.29,5.28,2.4,0.01,"up","yes"]
["chr1",244853406,244863106,"HNRNPU",1.37,7.18,5.24,2.39,0.01,"up","yes"]
["chr8",143580034,143597362,"EEF1D",1.17,6.33,5.42,2.44,0.01,"up","yes"]
["chr14",105851708,105856218,"IGHM",3.29,17.14,5.21,2.38,0.01,"up","yes"]
["chr3",184180509,184184065,"AP2M1",1.41,7.51,5.31,2.41,0.01,"up","yes"]
["chr3",72749279,72848480,"SHQ1",0.3,1.66,5.45,2.45,0.01,"up","yes"]
["chr2",131492813,131520421,"AC073869.1",0.36,1.95,5.39,2.43,0.01,"up","yes"]
["chrX",120526396,120561440,"CUL4B",0.38,2.06,5.4,2.43,0.01,"up","yes"]
["chr19",8521104,8577438,"MYO1F",0.6,3.13,5.22,2.38,0.01,"up","yes"]
["chr17",35587285,35726280,"AP2B1",0.36,1.91,5.25,2.39,0.01,"up","yes"]
["chr16",89722869,89738589,"ZNF276",0.52,2.83,5.4,2.43,0.01,"up","yes"]
["chr21",33267928,33296953,"IL10RB",0.52,2.83,5.39,2.43,0.01,"up","yes"]
["chr19",35154743,35169883,"FXYD5",29.73,150.76,5.07,2.34,0.01,"up","yes"]
["chr9",120902393,120928769,"TRAF1",1.43,7.26,5.08,2.34,0.01,"up","yes"]
["chr8",23429152,23457695,"ENTPD4",0.39,2.04,5.17,2.37,0.01,"up","yes"]
["chr7",816649,874413,"SUN1",1.26,6.4,5.09,2.35,0.01,"up","yes"]
["chr20",50081124,50113173,"UBE2V1",8.51,42.96,5.05,2.34,0.01,"up","yes"]
["chr12",56158362,56160795,"MYL6",0.6,3.23,5.42,2.44,0.01,"up","yes"]
["chr12",76036587,76085033,"NAP1L1",0.21,1.1,5.11,2.35,0.01,"up","yes"]
["chr7",92091989,92110668,"AKAP9",0.29,1.5,5.25,2.39,0.01,"up","yes"]
["chr1",154582061,154608102,"ADAR",0.49,2.51,5.1,2.35,0.01,"up","yes"]
["chr14",22767282,22771761,"OXA1L",1.43,7.29,5.1,2.35,0.01,"up","yes"]
["chr14",105769102,105771405,"IGHG3",7.77,39.06,5.03,2.33,0.01,"up","yes"]
["chr22",41125864,41180083,"EP300",0.44,2.24,5.08,2.34,0.01,"up","yes"]
["chr2",84837790,84881150,"TRABD2A",1.15,5.93,5.16,2.37,0.01,"up","yes"]
["chr22",20993664,20998129,"LZTR1",1.08,5.54,5.11,2.35,0.01,"up","yes"]
["chr10",102854223,102864961,"BORCS7",0.45,2.35,5.28,2.4,0.01,"up","yes"]
["chr22",30970677,30976063,"TUG1",0.33,1.75,5.28,2.4,0.01,"up","yes"]
["chr19",57633167,57642779,"ZNF211",0.54,2.76,5.14,2.36,0.01,"up","yes"]
["chr1",24415803,24472976,"NIPAL3",0.59,2.94,5.02,2.33,0.01,"up","yes"]
["chr6",27450743,27473118,"ZNF184",0.6,3.02,5.07,2.34,0.01,"up","yes"]
["chr5",111224086,111494886,"CAMK4",0.73,3.64,4.97,2.31,0.01,"up","yes"]
["chr4",77055234,77056485,"CCNI",1.27,6.76,5.31,2.41,0.01,"up","yes"]
["chr11",10271234,10272259,"AC080023.2",0.84,4.39,5.25,2.39,0.01,"up","yes"]
["chr1",223701593,223776016,"CAPN2",0.88,4.42,5.01,2.33,0.01,"up","yes"]
["chr11",9384628,9445661,"IPO7",0.74,3.71,5.01,2.32,0.01,"up","yes"]
["chr15",66501560,66504833,"RPL4",0.86,4.55,5.26,2.39,0.01,"up","yes"]
["chr2",88846694,89320146,"IGKV1-39",4.96,24.53,4.95,2.31,0.01,"up","yes"]
["chr4",102577714,102617098,"NFKB1",0.57,2.87,5.01,2.32,0.01,"up","yes"]
["chr4",39454137,39458888,"RPL9",7.82,38.5,4.92,2.3,0.01,"up","yes"]
["chr16",8852943,8869012,"CARHSP1",0.25,1.36,5.32,2.41,0.01,"up","yes"]
["chr21",33552248,33577481,"SON",0.22,1.13,5.14,2.36,0.01,"up","yes"]
["chr11",313853,315272,"IFITM1",8.54,42.01,4.92,2.3,0.01,"up","yes"]
["chr12",8940363,8949774,"M6PR",5.09,24.87,4.89,2.29,0.01,"up","yes"]
["chr9",73151757,73170393,"ANXA1",1.64,8.14,4.98,2.32,0.01,"up","yes"]
["chr11",118193740,118225094,"JAML",13.44,65.47,4.87,2.28,0.01,"up","yes"]
["chr12",50979535,51026359,"SLC11A2",0.27,1.38,5.15,2.37,0.01,"up","yes"]
["chr10",125719702,125749096,"EDRF1",0.21,1.1,5.2,2.38,0.01,"up","yes"]
["chr11",117363955,117413266,"CEP164",0.22,1.1,5.08,2.34,0.01,"up","yes"]
["chr12",56158161,56161574,"MYL6",1.5,7.59,5.06,2.34,0.01,"up","yes"]
["chr1",206685304,206734285,"MAPKAPK2",1.4,6.87,4.91,2.29,0.01,"up","yes"]
["chr9",91409045,91423862,"NFIL3",1.29,6.39,4.94,2.3,0.01,"up","yes"]
["chr22",38734537,38755956,"SUN2",8.57,41.11,4.8,2.26,0.01,"up","yes"]
["chr11",130230969,130314591,"ZBTB44",0.46,2.28,4.99,2.32,0.01,"up","yes"]
["chr5",179614181,179623169,"HNRNPH1",0.51,2.57,5.06,2.34,0.01,"up","yes"]
["chr19",47309728,47322076,"C5AR1",0.37,1.89,5.06,2.34,0.01,"up","yes"]
["chr22",50446826,50455989,"SBF1",0.46,2.33,5.08,2.35,0.01,"up","yes"]
["chr12",53461015,53476070,"PCBP2",1.62,7.86,4.86,2.28,0.01,"up","yes"]
["chr6",32190766,32192885,"GPSM3",9.83,47.14,4.79,2.26,0.01,"up","yes"]
["chr14",22473237,22552158,"TRAC",3.22,15.55,4.83,2.27,0.01,"up","yes"]
["chr18",49488561,49492432,"RPL17",4.4,21.42,4.87,2.28,0.01,"up","yes"]
["chr9",120406146,120536437,"CDK5RAP2",0.26,1.26,4.95,2.31,0.01,"up","yes"]
["chr1",207043849,207051077,"YOD1",0.35,1.73,4.9,2.29,0.01,"up","yes"]
["chr9",127445377,127451419,"RPL12",1.43,6.88,4.81,2.27,0.01,"up","yes"]
["chr16",89644463,89657709,"CHMP1A",0.61,3.02,4.91,2.3,0.01,"up","yes"]
["chr20",37983007,38033461,"TTI1",0.5,2.46,4.87,2.28,0.01,"up","yes"]
["chr1",42846573,42852473,"ZNF691",0.43,2.16,5.02,2.33,0.01,"up","yes"]
["chr6",57090010,57170307,"ZNF451",0.59,2.85,4.82,2.27,0.01,"up","yes"]
["chr5",146447311,146480216,"TCERG1",0.54,2.69,5.02,2.33,0.01,"up","yes"]
["chr5",134115610,134146573,"TCF7",9.28,43.98,4.74,2.25,0.01,"up","yes"]
["chr19",41549520,41550705,"AC243960.1",2.17,10.72,4.95,2.31,0.01,"up","yes"]
["chr11",66638672,66646452,"RBM4",2.69,12.83,4.77,2.25,0.01,"up","yes"]
["chr19",19192846,19197434,"RFXANK",0.74,3.76,5.06,2.34,0.01,"up","yes"]
["chr19",36114986,36125945,"TBCB",2.14,10.24,4.79,2.26,0.01,"up","yes"]
["chr19",19385833,19508931,"GATAD2A",0.26,1.26,4.87,2.29,0.01,"up","yes"]
["chr22",22887829,22895825,"IGLL5",1.05,5.28,5.03,2.33,0.01,"up","yes"]
["chr4",57009559,57031158,"POLR2B",0.8,3.83,4.79,2.26,0.01,"up","yes"]
["chr14",92703809,92748702,"LGMN",0.4,1.98,4.97,2.31,0.01,"up","yes"]
["chr17",3033081,3037738,"RAP1GAP2",0.46,2.23,4.81,2.27,0.01,"up","yes"]
["chr3",129555214,129558697,"PLXND1",1.32,6.35,4.82,2.27,0.01,"up","yes"]
["chr6",30184455,30213427,"TRIM26",1.58,7.49,4.74,2.25,0.01,"up","yes"]
["chr20",63284292,63289788,"ARFGAP1",0.32,1.58,5,2.32,0.01,"up","yes"]
["chr3",70959185,71481853,"FOXP1",1.04,4.99,4.79,2.26,0.01,"up","yes"]
["chrX",73820651,73851091,"XIST",0.31,1.56,5.01,2.33,0.01,"up","yes"]
["chr1",154156364,154183208,"TPM3",1.32,6.3,4.77,2.25,0.01,"up","yes"]
["chr12",112027788,112108785,"NAA25",0.33,1.6,4.8,2.26,0.01,"up","yes"]
["chr6",28267010,28278221,"ZSCAN26",0.56,2.71,4.81,2.27,0.01,"up","yes"]
["chr12",56595930,56636379,"BAZ2A",1.15,5.36,4.68,2.23,0.01,"up","yes"]
["chr11",3711835,3797547,"NUP98",0.58,2.74,4.76,2.25,0.01,"up","yes"]
["chr11",2301995,2318282,"TSPAN32",0.69,3.34,4.87,2.28,0.01,"up","yes"]
["chr8",11844094,11868112,"CTSB",2.02,9.54,4.72,2.24,0.01,"up","yes"]
["chr4",36281622,36344785,"DTHD1",0.24,1.17,4.93,2.3,0.01,"up","yes"]
["chr5",132410636,132476044,"C5orf56",0.81,4.03,4.98,2.32,0.01,"up","yes"]
["chrX",72272713,72276227,"RPS4X",2.67,12.51,4.68,2.23,0.01,"up","yes"]
["chr11",20363797,20383783,"HTATIP2",0.77,3.74,4.85,2.28,0.01,"up","yes"]
["chr12",95474162,95514326,"METAP2",1.13,5.38,4.74,2.24,0.01,"up","yes"]
["chr3",9442170,9476154,"SETD5",0.23,1.13,4.87,2.29,0.01,"up","yes"]
["chr9",137241288,137243706,"TUBB4B",0.42,2.04,4.91,2.3,0.01,"up","yes"]
["chr4",1169763,1171070,"SPON2",0.89,4.37,4.89,2.29,0.01,"up","yes"]
["chr11",65375194,65382646,"SLC25A45",0.23,1.1,4.77,2.25,0.01,"up","yes"]
["chr3",49014239,49014981,"WDR6",1.65,8.05,4.89,2.29,0.01,"up","yes"]
["chr1",1324767,1328897,"CPTP",1.02,4.81,4.71,2.24,0.01,"up","yes"]
["chr16",85613352,85676204,"GSE1",1.1,5.07,4.61,2.2,0.01,"up","yes"]
["chr8",58553214,58581886,"SDCBP",6.08,28.02,4.61,2.2,0.01,"up","yes"]
["chr13",49628299,49633872,"ARL11",0.44,2.09,4.75,2.25,0.01,"up","yes"]
["chr12",64610513,64697567,"RASSF3",8.05,36.79,4.57,2.19,0.01,"up","yes"]
["chr22",24011418,24178628,"CABIN1",1.13,5.18,4.59,2.2,0.01,"up","yes"]
["chr15",52313304,52528841,"MYO5A",0.68,3.13,4.62,2.21,0.01,"up","yes"]
["chr22",17638584,17730855,"BCL2L13",0.22,1.07,4.78,2.26,0.01,"up","yes"]
["chr22",29268326,29300336,"EWSR1",0.99,4.64,4.7,2.23,0.02,"up","yes"]
["chr15",88636153,88655621,"ISG20",1.82,8.58,4.71,2.23,0.02,"up","yes"]
["chr17",3923870,3964464,"ATP2A3",0.69,3.2,4.61,2.21,0.02,"up","yes"]
["chr17",7572826,7582024,"AC016876.2",0.47,2.18,4.63,2.21,0.02,"up","yes"]
["chr13",30460895,30464247,"HMGB1",2.33,10.72,4.59,2.2,0.02,"up","yes"]
["chr2",62705742,63046487,"EHBP1",0.23,1.07,4.75,2.25,0.02,"up","yes"]
["chr11",62676498,62679090,"UBXN1",13.28,60.11,4.53,2.18,0.02,"up","yes"]
["chr11",65860860,65866417,"MUS81",0.75,3.54,4.71,2.24,0.02,"up","yes"]
["chr16",1776722,1782594,"SPSB3",0.41,1.99,4.89,2.29,0.02,"up","yes"]
["chr9",107484852,107489437,"KLF4",0.32,1.53,4.82,2.27,0.02,"up","yes"]
["chr2",97737822,97738577,"ZAP70",1.12,5.43,4.87,2.28,0.02,"up","yes"]
["chr12",120446438,120463749,"GATC",0.28,1.3,4.72,2.24,0.02,"up","yes"]
["chr1",160485030,160523262,"SLAMF6",2.38,10.75,4.53,2.18,0.02,"up","yes"]
["chr14",65075126,65102248,"MAX",8.5,38.22,4.5,2.17,0.02,"up","yes"]
["chr14",106005095,106005574,"IGHV1-3",2.97,13.93,4.69,2.23,0.02,"up","yes"]
["chr17",44191805,44198070,"ATXN7L3",0.61,2.78,4.58,2.19,0.02,"up","yes"]
["chr19",18859383,18868229,"UPF1",0.88,4,4.54,2.18,0.02,"up","yes"]
["chr17",4967997,4987654,"CAMTA2",2.72,12.17,4.48,2.16,0.02,"up","yes"]
["chr14",91780955,91836447,"TC2N",0.75,3.4,4.56,2.19,0.02,"up","yes"]
["chr13",41311205,41377030,"NAA16",0.36,1.65,4.63,2.21,0.02,"up","yes"]
["chr22",29327865,29388583,"AP1B1",0.27,1.27,4.68,2.23,0.02,"up","yes"]
["chr1",185297015,185317273,"IVNS1ABP",0.52,2.37,4.58,2.19,0.02,"up","yes"]
["chr10",6202931,6235532,"PFKFB3",0.58,2.63,4.51,2.17,0.02,"up","yes"]
["chr12",57694023,57721631,"OS9",1.72,7.68,4.48,2.16,0.02,"up","yes"]
["chr19",10271093,10285583,"ICAM1",0.7,3.29,4.67,2.22,0.02,"up","yes"]
["chrX",55009113,55020433,"ALAS2",1.28,5.92,4.62,2.21,0.02,"up","yes"]
["chr7",75418796,75442719,"POM121C",0.91,4.05,4.47,2.16,0.02,"up","yes"]
["chr3",51957454,51967457,"PCBP4",0.56,2.56,4.59,2.2,0.02,"up","yes"]
["chr3",152243506,152465782,"MBNL1",1.68,7.4,4.41,2.14,0.02,"up","yes"]
["chr2",203867786,203873960,"CTLA4",0.39,1.87,4.74,2.24,0.02,"up","yes"]
["chr12",57096365,57111374,"STAT6",0.89,4,4.48,2.16,0.02,"up","yes"]
["chr20",46366050,46406559,"ELMO2",0.22,1.03,4.63,2.21,0.02,"up","yes"]
["chr1",161623196,161631963,"FCGR3B",21.39,93.43,4.37,2.13,0.02,"up","yes"]
["chr12",89349072,89351171,"DUSP6",1.13,5.14,4.56,2.19,0.02,"up","yes"]
["chr16",89508411,89537721,"SPG7",0.32,1.51,4.67,2.22,0.02,"up","yes"]
["chr3",111542118,111652241,"CD96",0.37,1.67,4.51,2.17,0.02,"up","yes"]
["chr19",2269534,2273331,"OAZ1",4.95,21.77,4.4,2.14,0.02,"up","yes"]
["chr9",5919022,6007787,"KIAA2026",0.29,1.29,4.46,2.16,0.02,"up","yes"]
["chr1",87331781,87345015,"LMO4",0.91,4.24,4.65,2.22,0.02,"up","yes"]
["chr12",79775929,79934931,"PPP1R12A",0.79,3.51,4.45,2.15,0.02,"up","yes"]
["chr8",1761990,1764339,"AC100810.1",0.73,3.42,4.7,2.23,0.02,"up","yes"]
["chr10",100977821,100987497,"MRPL43",0.52,2.37,4.56,2.19,0.02,"up","yes"]
["chr1",202149851,202158569,"PTPN7",0.46,2.16,4.66,2.22,0.02,"up","yes"]
["chr12",57757487,57759416,"9-Mar",0.59,2.67,4.55,2.19,0.02,"up","yes"]
["chr7",44044702,44060939,"DBNL",0.72,3.28,4.56,2.19,0.02,"up","yes"]
["chr10",128047565,128085369,"PTPRE",1.93,8.39,4.34,2.12,0.02,"up","yes"]
["chr16",71895543,71929010,"IST1",1.05,4.6,4.38,2.13,0.02,"up","yes"]
["chr1",77948405,77979086,"FUBP1",2.24,9.71,4.33,2.11,0.02,"up","yes"]
["chr18",3449704,3458411,"TGIF1",1.16,5.08,4.39,2.13,0.02,"up","yes"]
["chr15",34525207,34536010,"GOLGA8B",0.64,2.8,4.36,2.12,0.02,"up","yes"]
["chr20",43667157,43716496,"MYBL2",0.6,2.67,4.42,2.15,0.02,"up","yes"]
["chr12",108515185,108521210,"FICD",0.22,1.03,4.63,2.21,0.02,"up","yes"]
["chr1",15617500,15669044,"DDI2",0.55,2.39,4.31,2.11,0.02,"up","yes"]
["chr10",95711779,95869695,"ENTPD1",0.65,2.82,4.35,2.12,0.02,"up","yes"]
["chr17",82314874,82317552,"CD7",3.09,13.33,4.31,2.11,0.02,"up","yes"]
["chr19",18573265,18575241,"UBA52",3.33,14.58,4.38,2.13,0.02,"up","yes"]
["chr4",82818661,82891153,"SEC31A",0.27,1.22,4.49,2.17,0.02,"up","yes"]
["chr19",54354675,54364865,"LAIR1",1.21,5.32,4.39,2.14,0.02,"up","yes"]
["chr9",112218435,112333667,"PTBP3",1.24,5.32,4.28,2.1,0.02,"up","yes"]
["chr5",40832458,40835186,"RPL37",46.36,197.7,4.26,2.09,0.02,"up","yes"]
["chr22",38745687,38756000,"SUN2",1.07,4.79,4.49,2.17,0.02,"up","yes"]
["chr1",151404802,151459179,"POGZ",0.48,2.09,4.36,2.12,0.02,"up","yes"]
["chr17",7012603,7017522,"RNASEK-C17orf49",8.89,37.87,4.26,2.09,0.02,"up","yes"]
["chr2",68041130,68062983,"C1D",0.5,2.21,4.47,2.16,0.02,"up","yes"]
["chr14",97957930,97978110,"LINC01550",0.29,1.33,4.59,2.2,0.02,"up","yes"]
["chr7",74754096,74760690,"GTF2I",0.33,1.45,4.42,2.14,0.02,"up","yes"]
["chr20",63708053,63739107,"AL121845.3",2.54,10.8,4.26,2.09,0.02,"up","yes"]
["chr1",52056304,52088418,"BTF3L4",0.42,1.89,4.5,2.17,0.02,"up","yes"]
["chr1",17067786,17083426,"PADI2",0.27,1.2,4.47,2.16,0.02,"up","yes"]
["chr1",151874055,151909502,"THEM4",0.6,2.66,4.43,2.15,0.02,"up","yes"]
["chr11",47408631,47416496,"SLC39A13",0.36,1.6,4.52,2.18,0.02,"up","yes"]
["chr1",40040732,40066314,"CAP1",1.1,4.95,4.52,2.18,0.02,"up","yes"]
["chr7",142855124,142871094,"EPHB6",0.48,2.08,4.3,2.1,0.02,"up","yes"]
["chr3",50336377,50340980,"RASSF1",0.57,2.53,4.41,2.14,0.02,"up","yes"]
["chr15",71822289,72118081,"MYO9A",0.31,1.31,4.26,2.09,0.02,"up","yes"]
["chr7",7968782,8086646,"GLCCI1",1.62,6.92,4.27,2.09,0.02,"up","yes"]
["chr1",19251539,19260128,"MRTO4",0.87,3.77,4.32,2.11,0.02,"up","yes"]
["chr3",184314542,184335351,"EIF4G1",1.85,7.79,4.21,2.08,0.02,"up","yes"]
["chr19",41877305,41880980,"CD79A",1.94,8.48,4.37,2.13,0.02,"up","yes"]
["chr20",2873489,3039076,"PTPRA",3.08,12.89,4.19,2.07,0.02,"up","yes"]
["chr1",25861210,25871253,"PAQR7",0.58,2.51,4.31,2.11,0.02,"up","yes"]
["chr10",28533222,28619987,"WAC",7.45,31.12,4.17,2.06,0.02,"up","yes"]
["chr19",58309030,58315203,"AC020915.1",0.49,2.12,4.3,2.1,0.02,"up","yes"]
["chr22",36140330,36160929,"APOL3",0.42,1.85,4.36,2.13,0.02,"up","yes"]
["chr2",74526689,74529685,"AUP1",6.23,26,4.17,2.06,0.02,"up","yes"]
["chr20",47209214,47356706,"ZMYND8",0.93,3.89,4.2,2.07,0.02,"up","yes"]
["chr19",10512947,10517931,"S1PR5",0.44,1.92,4.39,2.13,0.02,"up","yes"]
["chr19",647530,650594,"RNF126",0.48,2.11,4.37,2.13,0.02,"up","yes"]
["chr17",42563307,42566274,"COASY",0.48,2.09,4.35,2.12,0.02,"up","yes"]
["chr12",55743280,55757278,"GDF11",0.37,1.54,4.2,2.07,0.02,"up","yes"]
["chr6",30740254,30742706,"FLOT1",2.48,10.42,4.21,2.07,0.02,"up","yes"]
["chr1",70237481,70250998,"SRSF11",0.69,3.07,4.44,2.15,0.02,"up","yes"]
["chr14",106235064,106235594,"IGHV3-21",2.3,9.98,4.33,2.12,0.03,"up","yes"]
["chr1",44777903,44778739,"RPS8",5.22,21.96,4.21,2.07,0.03,"up","yes"]
["chr15",66499320,66504846,"RPL4",0.46,2.03,4.37,2.13,0.03,"up","yes"]
["chr12",57253776,57430808,"R3HDM2",1.14,4.74,4.14,2.05,0.03,"up","yes"]
["chr22",29290830,29300525,"EWSR1",0.95,3.97,4.19,2.07,0.03,"up","yes"]
["chr14",23058567,23095614,"ACIN1",0.92,3.81,4.13,2.05,0.03,"up","yes"]
["chr16",625614,629272,"RAB40C",0.73,3.09,4.22,2.08,0.03,"up","yes"]
["chr16",84218,113571,"NPRL3",4.17,17.13,4.11,2.04,0.03,"up","yes"]
["chr19",12272329,12294887,"ZNF44",0.34,1.5,4.4,2.14,0.03,"up","yes"]
["chr6",32190766,32192868,"GPSM3",7.95,32.55,4.09,2.03,0.03,"up","yes"]
["chr14",23058567,23095153,"ACIN1",1.02,4.19,4.12,2.04,0.03,"up","yes"]
["chr4",82424629,82429441,"HNRNPDL",9.13,37.35,4.09,2.03,0.03,"up","yes"]
["chr11",113314602,113366386,"TTC12",0.25,1.1,4.43,2.15,0.03,"up","yes"]
["chr12",51281038,51324115,"BIN2",0.45,1.97,4.33,2.11,0.03,"up","yes"]
["chr10",101578882,101588126,"POLL",1.01,4.22,4.16,2.06,0.03,"up","yes"]
["chr7",100428817,100434117,"MEPCE",0.42,1.8,4.3,2.1,0.03,"up","yes"]
["chr4",108620569,108625554,"RPL34",1.79,7.72,4.3,2.11,0.03,"up","yes"]
["chr19",14736079,14776756,"ADGRE2",0.67,2.81,4.18,2.06,0.03,"up","yes"]
["chr11",63938996,63957328,"NAA40",0.54,2.25,4.16,2.06,0.03,"up","yes"]
["chr16",81040525,81047346,"ATMIN",0.63,2.59,4.12,2.04,0.03,"up","yes"]
["chr12",49741557,49764933,"TMBIM6",16.74,67.79,4.05,2.02,0.03,"up","yes"]
["chrX",44873511,45112602,"KDM6A",0.33,1.37,4.19,2.07,0.03,"up","yes"]
["chr7",70698567,70792487,"AUTS2",0.37,1.53,4.18,2.06,0.03,"up","yes"]
["chr2",85318020,85328296,"TGOLN2",0.53,2.17,4.09,2.03,0.03,"up","yes"]
["chrX",72181679,72198344,"PIN4",0.93,3.93,4.21,2.07,0.03,"up","yes"]
["chr2",219498888,219506935,"GMPPA",0.59,2.48,4.22,2.08,0.03,"up","yes"]
["chr12",123633829,123662606,"GTF2H3",0.4,1.69,4.2,2.07,0.03,"up","yes"]
["chrX",153334155,153352926,"ZNF275",0.51,2.09,4.07,2.03,0.03,"up","yes"]
["chr2",237692145,237765279,"LRRFIP1",10.28,41.24,4.01,2,0.03,"up","yes"]
["chr11",67303448,67312600,"SSH3",0.39,1.64,4.19,2.07,0.03,"up","yes"]
["chr11",61964585,61967607,"FTH1",40,160.12,4,2,0.03,"up","yes"]
["chr19",52570275,52584566,"ZNF701",0.4,1.71,4.23,2.08,0.03,"up","yes"]
["chr22",31160193,31207019,"RNF185",1.02,4.16,4.06,2.02,0.03,"up","yes"]
["chr8",86374041,86467476,"WWP1",0.56,2.31,4.11,2.04,0.03,"up","yes"]
["chr3",133573730,133590261,"CDV3",4.01,16.06,4.01,2,0.03,"up","yes"]
["chr1",155247396,155255483,"FAM189B",0.51,2.18,4.27,2.1,0.03,"up","yes"]
["chr19",35904398,35908519,"TYROBP",7.98,32.15,4.03,2.01,0.03,"up","yes"]
["chr7",141656728,141702153,"KIAA1147",1.27,5.09,4,2,0.03,"up","yes"]
["chr1",155947942,155978427,"ARHGEF2",4.92,19.63,3.99,2,0.03,"up","yes"]
["chr11",61964566,61967631,"FTH1",30.07,119.7,3.98,1.99,0.03,"up","yes"]
["chr21",45171642,45226560,"ADARB1",0.33,1.35,4.07,2.02,0.03,"up","yes"]
["chr9",98084355,98119198,"TRIM14",4.04,16.09,3.98,1.99,0.03,"up","yes"]
["chr7",26190225,26200755,"HNRNPA2B1",16.39,64.99,3.96,1.99,0.03,"up","yes"]
["chr16",2767507,2770258,"SRRM2",0.83,3.43,4.13,2.05,0.03,"up","yes"]
["chr3",197791264,197883772,"LRCH3",0.67,2.75,4.1,2.04,0.03,"up","yes"]
["chr2",231708530,231713506,"PTMA",6.33,25.1,3.97,1.99,0.03,"up","yes"]
["chr4",1009979,1026891,"FGFRL1",0.56,2.27,4.05,2.02,0.03,"up","yes"]
["chr11",118304730,118313341,"CD3E",0.76,3.26,4.27,2.09,0.03,"up","yes"]
["chr9",36136785,36163913,"GLIPR2",1.07,4.33,4.06,2.02,0.03,"up","yes"]
["chr3",100709378,100748927,"TFG",0.61,2.54,4.18,2.06,0.03,"up","yes"]
["chr7",100435282,100436423,"PPP1R35",1.05,4.33,4.14,2.05,0.03,"up","yes"]
["chr21",46098097,46132849,"COL6A2",1.37,5.44,3.97,1.99,0.03,"up","yes"]
["chr10",70597349,70602775,"PRF1",1.22,4.86,4,2,0.03,"up","yes"]
["chr14",20989994,20997010,"METTL17",0.83,3.37,4.07,2.02,0.03,"up","yes"]
["chr17",1650631,1684837,"PRPF8",0.97,3.83,3.94,1.98,0.03,"up","yes"]
["chr6",170554302,170566957,"TBP",1.42,5.78,4.08,2.03,0.03,"up","yes"]
["chr12",76351800,76559809,"OSBPL8",0.3,1.19,3.99,2,0.03,"up","yes"]
["chr19",1609293,1650278,"TCF3",0.53,2.09,3.98,1.99,0.03,"up","yes"]
["chr11",61964601,61967166,"FTH1",32.75,127.84,3.9,1.96,0.03,"up","yes"]
["chr17",39904596,39919854,"GSDMB",0.38,1.53,4.02,2.01,0.03,"up","yes"]
["chr4",73981069,73988283,"PPBP",4.06,16.04,3.95,1.98,0.03,"up","yes"]
["chr14",22946228,22957154,"HAUS4",1.5,5.97,3.97,1.99,0.03,"up","yes"]
["chr7",105116377,105269015,"SRPK2",0.46,1.85,4,2,0.03,"up","yes"]
["chr19",39391311,39400637,"MED29",0.73,2.9,3.96,1.99,0.03,"up","yes"]
["chr12",120461711,120464943,"SRSF9",0.7,2.87,4.1,2.04,0.03,"up","yes"]
["chr8",11769739,11787346,"NEIL2",0.29,1.21,4.18,2.06,0.03,"up","yes"]
["chr4",7043391,7057952,"TADA2B",1.3,5.08,3.92,1.97,0.03,"up","yes"]
["chr2",89142574,89143160,"IGKV3-20",4.7,18.72,3.98,1.99,0.03,"up","yes"]
["chr1",151364305,151372700,"SELENBP1",0.44,1.85,4.18,2.06,0.03,"up","yes"]
["chr5",102866116,103029165,"PAM",0.24,1,4.2,2.07,0.03,"up","yes"]
["chr12",56310428,56316336,"CNPY2",1.75,6.98,3.99,2,0.03,"up","yes"]
["chr19",7439688,7472477,"ARHGEF18",0.31,1.24,3.99,2,0.03,"up","yes"]
["chr19",3359647,3463142,"NFIC",1.12,4.47,4,2,0.03,"up","yes"]
["chr17",44207240,44218502,"UBTF",1.94,7.57,3.91,1.97,0.03,"up","yes"]
["chr22",30971066,30979395,"TUG1",1.76,6.81,3.88,1.95,0.03,"up","yes"]
["chr19",16829407,16880353,"SIN3B",0.59,2.3,3.93,1.97,0.03,"up","yes"]
["chr4",82818662,82891214,"SEC31A",0.25,1,4.04,2.01,0.03,"up","yes"]
["chr2",8721081,8837630,"KIDINS220",0.66,2.56,3.88,1.96,0.03,"up","yes"]
["chr17",4945652,4949014,"PFN1",96.89,372.56,3.85,1.94,0.03,"up","yes"]
["chr3",33388336,33440378,"UBP1",1.32,5.1,3.88,1.96,0.03,"up","yes"]
["chr11",105024755,105035206,"CASP1",0.58,2.29,3.94,1.98,0.04,"up","yes"]
["chr9",110048696,110172512,"AKAP2",0.85,3.28,3.87,1.95,0.04,"up","yes"]
["chr17",44076746,44123638,"HDAC5",1,3.88,3.87,1.95,0.04,"up","yes"]
["chr11",71479294,71501539,"NADSYN1",1.15,4.5,3.9,1.96,0.04,"up","yes"]
["chr11",66510609,66533627,"BBS1",0.4,1.6,3.99,2,0.04,"up","yes"]
["chr16",2253915,2268105,"RNPS1",1.32,5.24,3.97,1.99,0.04,"up","yes"]
["chr5",134137865,134139252,"TCF7",1.12,4.56,4.08,2.03,0.04,"up","yes"]
["chrX",73827801,73842110,"XIST",1.2,4.73,3.93,1.98,0.04,"up","yes"]
["chr1",158931559,158976728,"PYHIN1",0.78,3.12,3.97,1.99,0.04,"up","yes"]
["chr22",20573678,20587617,"MED15",0.63,2.44,3.89,1.96,0.04,"up","yes"]
["chr22",22758700,22759218,"IGLV2-14",4.25,16.57,3.9,1.96,0.04,"up","yes"]
["chr5",139293778,139330441,"MATR3",1.24,4.75,3.83,1.94,0.04,"up","yes"]
["chr15",56087283,56243795,"RFX7",0.7,2.66,3.82,1.93,0.04,"up","yes"]
["chr7",105605067,105876604,"ATXN7L1",0.61,2.36,3.85,1.94,0.04,"up","yes"]
["chr17",7839904,7854796,"KDM6B",2.36,8.96,3.8,1.92,0.04,"up","yes"]
["chr1",52896223,52921762,"ECHDC2",0.44,1.75,3.97,1.99,0.04,"up","yes"]
["chr8",127736220,127741372,"MYC",0.52,2.07,3.96,1.99,0.04,"up","yes"]
["chr20",4148779,4187746,"SMOX",1.05,4.06,3.86,1.95,0.04,"up","yes"]
["chr9",128261172,128275995,"GOLGA2",0.63,2.54,4.03,2.01,0.04,"up","yes"]
["chr3",122421949,122514928,"KPNA1",1.34,5.1,3.79,1.92,0.04,"up","yes"]
["chr2",95402726,95416616,"FAHD2A",0.38,1.49,3.9,1.96,0.04,"up","yes"]
["chrX",136873958,136880725,"RBMX",2.4,9.14,3.8,1.93,0.04,"up","yes"]
["chr19",54449187,54462037,"LENG8",2.78,10.5,3.77,1.92,0.04,"up","yes"]
["chr12",53380194,53411630,"SP1",3.38,12.79,3.78,1.92,0.04,"up","yes"]
["chr12",53191323,53207282,"ITGB7",0.43,1.7,3.94,1.98,0.04,"up","yes"]
["chr14",24114780,24125240,"DCAF11",0.99,3.76,3.81,1.93,0.04,"up","yes"]
["chr10",119571802,119596495,"TIAL1",1.22,4.62,3.79,1.92,0.04,"up","yes"]
["chr2",64989401,65023865,"SLC1A4",0.56,2.16,3.84,1.94,0.04,"up","yes"]
["chr16",24554477,24572860,"RBBP6",1.32,4.97,3.78,1.92,0.04,"up","yes"]
["chr17",1633858,1645747,"SCARF1",0.55,2.1,3.85,1.95,0.04,"up","yes"]
["chr11",62593842,62601275,"MTA2",0.86,3.32,3.87,1.95,0.04,"up","yes"]
["chr17",67947754,67981762,"BPTF",1.54,5.88,3.82,1.93,0.04,"up","yes"]
["chr13",27251583,27256568,"RPL21",59.55,223.28,3.75,1.91,0.04,"up","yes"]
["chr12",130789600,130839266,"STX2",0.49,1.89,3.87,1.95,0.04,"up","yes"]
["chr5",77072072,77087323,"ZBED3",0.29,1.14,3.87,1.95,0.04,"up","yes"]
["chr14",20469379,20477094,"PNP",4.94,18.6,3.77,1.91,0.04,"up","yes"]
["chr6",33318558,33323014,"DAXX",2.99,11.21,3.75,1.91,0.04,"up","yes"]
["chr12",113221438,113298585,"TPCN1",0.44,1.67,3.82,1.93,0.04,"up","yes"]
["chr1",236540247,236548280,"LGALS8",1.03,4.06,3.94,1.98,0.04,"up","yes"]
["chr1",228106679,228109283,"MRPL55",1.14,4.61,4.03,2.01,0.04,"up","yes"]
["chr14",75015487,75025274,"MLH3",0.83,3.33,3.99,2,0.04,"up","yes"]
["chr3",186783597,186789897,"EIF4A2",1.02,3.92,3.85,1.95,0.04,"up","yes"]
["chr7",77310751,77355630,"GSAP",0.75,2.88,3.82,1.93,0.04,"up","yes"]
["chr17",35809489,35847234,"TAF15",1.46,5.55,3.8,1.92,0.04,"up","yes"]
["chr19",8321158,8322946,"RPS28",2.63,9.95,3.78,1.92,0.04,"up","yes"]
["chr12",110375477,110403730,"ANAPC7",0.76,2.91,3.85,1.95,0.04,"up","yes"]
["chr11",66257703,66267805,"KLC2",0.92,3.51,3.81,1.93,0.04,"up","yes"]
["chr18",57600656,57622173,"NARS",0.65,2.48,3.81,1.93,0.04,"up","yes"]
["chr14",20455226,20457002,"APEX1",1.99,7.62,3.83,1.94,0.04,"up","yes"]
["chr3",44625040,44644220,"ZNF197",0.26,1.04,3.94,1.98,0.04,"up","yes"]
["chrX",154398367,154400811,"RPL10",1.02,4.07,3.98,1.99,0.04,"up","yes"]
["chr12",6445352,6451718,"CD27",1.07,4.18,3.89,1.96,0.04,"up","yes"]
["chr17",37517830,37609411,"SYNRG",0.81,3.04,3.74,1.9,0.04,"up","yes"]
["chr21",32601667,32612352,"C21orf59",0.62,2.45,3.96,1.98,0.04,"up","yes"]
["chr4",88257620,88284736,"PPM1K",0.9,3.37,3.73,1.9,0.04,"up","yes"]
["chr20",2873496,3038668,"PTPRA",2.11,7.85,3.73,1.9,0.04,"up","yes"]
["chr19",51410021,51417803,"SIGLEC10",2.06,7.67,3.73,1.9,0.04,"up","yes"]
["chr10",102743970,102816240,"WBP1L",2.81,10.42,3.7,1.89,0.04,"up","yes"]
["chr19",18174169,18178117,"IFI30",0.51,1.98,3.86,1.95,0.04,"up","yes"]
["chr3",49940007,50077249,"RBM6",1.05,3.96,3.78,1.92,0.04,"up","yes"]
["chr9",105244622,105439171,"SLC44A1",0.32,1.25,3.87,1.95,0.04,"up","yes"]
["chrX",48683008,48691428,"WAS",1.69,6.32,3.75,1.91,0.04,"up","yes"]
["chr9",273070,464526,"DOCK8",1.44,5.33,3.7,1.89,0.04,"up","yes"]
["chr20",63698643,63708013,"ARFRP1",0.86,3.25,3.76,1.91,0.04,"up","yes"]
["chr10",97737121,97760906,"ZFYVE27",0.43,1.66,3.83,1.94,0.04,"up","yes"]
["chr22",26527628,26570788,"TPST2",2.05,7.62,3.72,1.89,0.04,"up","yes"]
["chr3",100315863,100325234,"TBC1D23",0.39,1.52,3.93,1.98,0.04,"up","yes"]
["chr9",15422869,15462460,"SNAPC3",0.48,1.87,3.85,1.95,0.04,"up","yes"]
["chr14",105643068,105864313,"IGHG2",54.72,200.33,3.66,1.87,0.04,"up","yes"]
["chr14",69053825,69153003,"DCAF5",1.23,4.54,3.7,1.89,0.04,"up","yes"]
["chr11",117993008,117998945,"IL10RA",0.88,3.38,3.84,1.94,0.04,"up","yes"]
["chr14",92513774,92688994,"RIN3",5.69,20.79,3.65,1.87,0.04,"up","yes"]
["chr12",57472270,57478198,"ARHGAP9",1.82,6.71,3.69,1.88,0.05,"up","yes"]
["chrX",2486414,2500967,"ZBED1",0.58,2.16,3.72,1.89,0.05,"up","yes"]
["chr16",3065677,3069409,"IL32",1.2,4.7,3.93,1.97,0.05,"up","yes"]
["chr10",70597348,70602759,"PRF1",18.37,66.89,3.64,1.86,0.05,"up","yes"]
["chr3",197950557,197954120,"RPL35A",2.3,8.78,3.81,1.93,0.05,"up","yes"]
["chr16",89644435,89646880,"CHMP1A",0.73,2.73,3.76,1.91,0.05,"up","yes"]
["chr18",41955206,42087830,"PIK3C3",0.45,1.65,3.67,1.88,0.05,"up","yes"]
["chr19",29942251,30016608,"URI1",1.69,6.21,3.67,1.87,0.05,"up","yes"]
["chr2",47690656,47691272,"AC079250.1",8.95,32.9,3.68,1.88,0.05,"up","yes"]
["chrX",154398230,154402339,"RPL10",30.77,111.6,3.63,1.86,0.05,"up","yes"]
["chr1",211326837,211374946,"TRAF5",1.07,3.95,3.67,1.88,0.05,"up","yes"]
["chrX",71533104,71574655,"OGT",1.33,4.84,3.64,1.86,0.05,"up","yes"]
["chr15",74798652,74802589,"CSK",2.06,7.58,3.67,1.88,0.05,"up","yes"]
["chr7",100875188,100888664,"SRRT",1.86,6.79,3.64,1.87,0.05,"up","yes"]
["chr17",75261674,75266373,"MRPS7",2.44,8.95,3.67,1.88,0.05,"up","yes"]
["chr19",2070988,2096508,"MOB3A",6.85,24.78,3.62,1.86,0.05,"up","yes"]
["chrX",19535693,19799751,"SH3KBP1",10.22,36.96,3.62,1.85,0.05,"up","yes"]
["chr6",6144085,6320834,"F13A1",5.51,19.93,3.62,1.85,0.05,"up","yes"]
["chrX",101009350,101052054,"TRMT2B",0.93,3.42,3.67,1.88,0.05,"up","yes"]
["chr1",13704855,13825079,"PRDM2",0.77,2.79,3.64,1.86,0.05,"up","yes"]
["chr17",60677852,61392831,"BCAS3",0.75,2.75,3.66,1.87,0.05,"up","yes"]
["chr2",219229838,219236651,"ANKZF1",0.48,1.8,3.72,1.89,0.05,"up","yes"]
["chr18",45724127,45752520,"SLC14A1",0.6,2.22,3.68,1.88,0.05,"up","yes"]
["chr15",90388247,90500854,"IQGAP1",0.36,1.32,3.71,1.89,0.05,"up","yes"]
["chr16",66934471,66944306,"CES2",0.53,1.97,3.73,1.9,0.05,"up","yes"]
["chr19",18419355,18434562,"SSBP4",0.6,2.27,3.78,1.92,0.05,"up","yes"]
["chr14",91114063,91225632,"C14orf159",1.79,6.5,3.64,1.86,0.05,"up","yes"]
["chr5",50667557,50843374,"PARP8",0.45,1.68,3.7,1.89,0.05,"up","yes"]
["chr14",61695777,61748258,"HIF1A",1.95,7.05,3.62,1.86,0.05,"up","yes"]
["chr17",759452,782294,"GLOD4",0.27,1.06,3.88,1.96,0.05,"up","yes"]
["chr9",136410570,136423761,"PMPCA",1.35,4.91,3.65,1.87,0.05,"up","yes"]
["chr20",58889100,58911192,"GNAS",4.28,15.45,3.61,1.85,0.05,"up","yes"]
["chr11",60842071,60851081,"CCDC86",1.21,4.42,3.67,1.87,0.05,"up","yes"]
["chr1",6026013,6101192,"KCNAB2",1.75,6.31,3.6,1.85,0.05,"up","yes"]
["chrX",124346344,124373155,"SH2D1A",2.44,8.81,3.61,1.85,0.05,"up","yes"]
["chr3",186783577,186789881,"EIF4A2",1.06,3.9,3.67,1.88,0.05,"up","yes"]
["chr1",42846609,42852477,"ZNF691",0.45,1.74,3.85,1.94,0.05,"up","yes"]
["chr5",443233,471937,"EXOC3",0.49,1.78,3.63,1.86,0.05,"up","yes"]
["chr17",44257193,44268124,"SLC4A1",2.01,7.26,3.62,1.85,0.05,"up","yes"]
["chr14",106037902,106038365,"IGHV2-5",3.31,12.23,3.7,1.89,0.05,"up","yes"]
["chr11",61964566,61967633,"FTH1",40.47,144.19,3.56,1.83,0.05,"up","yes"]
["chr1",6026320,6098561,"KCNAB2",0.68,2.51,3.69,1.88,0.05,"up","yes"]
["chr10",110871807,110900006,"PDCD4",6.37,22.7,3.56,1.83,0.05,"up","yes"]
["chr18",63970029,63989371,"SERPINB8",0.64,2.34,3.65,1.87,0.05,"up","yes"]
["chr20",45891044,45898820,"CTSA",12.23,43.51,3.56,1.83,0.05,"up","yes"]
["chr7",116210506,116249577,"TES",0.86,3.27,3.8,1.93,0.05,"up","yes"]
["chr14",64914361,64934385,"CHURC1",0.5,1.85,3.69,1.89,0.05,"up","yes"]
["chr19",8209356,8262421,"CERS4",1.03,3.76,3.66,1.87,0.05,"up","yes"]
["chr2",86784610,86790895,"CD8A",5.15,18.35,3.57,1.83,0.05,"up","yes"]
["chrX",48574952,48577868,"RBM3",1.26,4.63,3.68,1.88,0.05,"up","yes"]
["chr12",54280780,54285251,"HNRNPA1",0.6,2.29,3.79,1.92,0.05,"up","yes"]
["chr6",31530219,31542017,"DDX39B",6.08,21.59,3.55,1.83,0.05,"up","yes"]
["chr10",96191702,96271540,"BLNK",0.66,2.45,3.71,1.89,0.05,"up","yes"]
["chr11",111352252,111379692,"POU2AF1",2.67,9.49,3.56,1.83,0.05,"up","yes"]
["chr17",17843511,17972410,"TOM1L2",0.58,2.09,3.59,1.84,0.05,"up","yes"]
["chr11",76656994,76665822,"AP001189.1",2.64,9.35,3.55,1.83,0.05,"up","yes"]
["chr9",127451486,127503501,"LRSAM1",0.39,1.44,3.65,1.87,0.05,"up","yes"]
["chr17",37518887,37609381,"SYNRG",0.8,2.87,3.57,1.84,0.05,"up","yes"]
["chr8",11844053,11868112,"CTSB",12.3,43.41,3.53,1.82,0.05,"up","yes"]
["chrX",55009089,55030977,"ALAS2",36.6,128.77,3.52,1.81,0.05,"up","yes"]
["chr16",1984213,1987749,"GFER",0.69,2.52,3.63,1.86,0.05,"up","yes"]
["chr8",127736594,127740958,"MYC",4.21,14.9,3.54,1.82,0.05,"up","yes"]
["chr19",35739257,35742411,"IGFLR1",1.31,4.76,3.64,1.87,0.05,"up","yes"]
["chr8",37858618,37899467,"RAB11FIP1",2.79,9.79,3.52,1.81,0.05,"up","yes"]
["chr6",31723326,31726714,"MPIG6B",2.74,9.69,3.53,1.82,0.05,"up","yes"]
["chr17",42562167,42566275,"COASY",3.33,11.74,3.53,1.82,0.05,"up","yes"]
["chr12",719244,720612,".",2.37,8.52,3.59,1.84,0.05,"up","yes"]
["chr20",48624249,48827769,"PREX1",32.88,0.2,0.01,-7.36,0,"down","yes"]
["chr19",4445007,4449604,"UBXN6",49.1,0.5,0.01,-6.61,0,"down","yes"]
["chr2",68774801,68826833,"ARHGAP25",27.28,0.33,0.01,-6.37,0,"down","yes"]
["chr11",5225461,5234569,"HBB",1941.31,32.6,0.02,-5.9,0,"down","yes"]
["chr14",100333788,100375644,"WARS",27.99,0.45,0.02,-5.96,0,"down","yes"]
["chr2",86784610,86791680,"CD8A",14.08,0.23,0.02,-5.96,0,"down","yes"]
["chr5",157477304,157575775,"ADAM19",17.42,0.3,0.02,-5.84,0,"down","yes"]
["chr22",37225261,37244432,"RAC2",118.1,2.1,0.02,-5.82,0,"down","yes"]
["chr3",69079202,69106128,"ARL6IP5",20.22,0.37,0.02,-5.79,0,"down","yes"]
["chr14",105643142,105864265,"IGHG2",23.2,0.44,0.02,-5.73,0,"down","yes"]
["chr18",2847195,2916531,"EMILIN2",10.63,0.21,0.02,-5.66,0,"down","yes"]
["chrX",47624214,47630305,"CFP",21.13,0.42,0.02,-5.67,0,"down","yes"]
["chr1",154582062,154608206,"ADAR",19.42,0.43,0.02,-5.49,0,"down","yes"]
["chr17",42700431,42745054,"EZH1",7.41,0.16,0.02,-5.57,0,"down","yes"]
["chr17",7240014,7251965,"CTDNEP1",89.59,2.07,0.02,-5.43,0,"down","yes"]
["chr16",172889,177137,"HBA2",1776.26,42.61,0.02,-5.38,0,"down","yes"]
["chr5",96663053,96772692,"CAST",16.09,0.37,0.02,-5.46,0,"down","yes"]
["chr17",82228445,82240086,"SLC16A3",19.88,0.47,0.02,-5.4,0,"down","yes"]
["chr11",10573178,10606229,"MRVI1",5.91,0.14,0.02,-5.41,0,"down","yes"]
["chr16",58520706,58629832,"CNOT1",4.8,0.12,0.02,-5.34,0,"down","yes"]
["chr8",95133804,95156684,"PLEKHF2",10.68,0.26,0.02,-5.38,0,"down","yes"]
["chr9",122371080,122395703,"PTGS1",6.03,0.15,0.02,-5.34,0,"down","yes"]
["chr11",108222832,108369099,"ATM",4.18,0.11,0.03,-5.28,0,"down","yes"]
["chr12",51238908,51243784,"DAZAP2",14.69,0.39,0.03,-5.25,0,"down","yes"]
["chr22",50523554,50532497,"TYMP",31.21,0.84,0.03,-5.22,0,"down","yes"]
["chr14",76151936,76214343,"GPATCH2L",2,0.05,0.02,-5.32,0,"down","yes"]
["chr6",33291654,33314387,"RGL2",16.3,0.45,0.03,-5.18,0,"down","yes"]
["chr6",132743870,132758008,"VNN2",103.1,2.93,0.03,-5.14,0,"down","yes"]
["chr6",29942245,29945884,"HLA-A",60.85,1.74,0.03,-5.13,0,"down","yes"]
["chr14",35401545,35404140,"NFKBIA",23.99,0.67,0.03,-5.16,0,"down","yes"]
["chr9",21003870,21031680,"HACD4",11.32,0.33,0.03,-5.12,0,"down","yes"]
["chr12",56663343,56688408,"PTGES3",14.69,0.43,0.03,-5.11,0,"down","yes"]
["chr2",108448561,108509398,"GCC2",4.35,0.13,0.03,-5.07,0,"down","yes"]
["chr18",2655750,2803588,"SMCHD1",39.11,1.27,0.03,-4.94,0,"down","yes"]
["chr6",159682139,159693241,"SOD2",38.95,1.21,0.03,-5,0,"down","yes"]
["chr6",132744026,132757970,"VNN2",17.04,0.53,0.03,-5.01,0,"down","yes"]
["chr19",41423896,41428730,"B3GNT8",9.21,0.29,0.03,-5,0,"down","yes"]
["chrX",109641337,109733403,"ACSL4",10.27,0.34,0.03,-4.9,0,"down","yes"]
["chr1",9651672,9729182,"PIK3CD",4.26,0.14,0.03,-4.97,0,"down","yes"]
["chr19",4536409,4540474,"LRG1",24.8,0.89,0.04,-4.8,0,"down","yes"]
["chr3",15003915,15049273,"NR2C2",4.19,0.15,0.03,-4.84,0,"down","yes"]
["chr12",40225074,40369281,"LRRK2",24.79,0.92,0.04,-4.76,0,"down","yes"]
["chr12",12326056,12350541,"MANSC1",3.5,0.12,0.03,-4.88,0,"down","yes"]
["chr14",55580317,55684579,"KTN1",4.51,0.15,0.03,-4.88,0,"down","yes"]
["chr16",84819991,84907112,"CRISPLD2",10.51,0.37,0.04,-4.83,0,"down","yes"]
["chr5",140631728,140633701,"CD14",47.73,1.82,0.04,-4.72,0,"down","yes"]
["chr17",78110458,78128697,"TMC6",4.17,0.15,0.04,-4.8,0,"down","yes"]
["chr14",71529325,71741229,"SIPA1L1",6.37,0.24,0.04,-4.72,0,"down","yes"]
["chr3",152243580,152463136,"MBNL1",29.06,1.13,0.04,-4.69,0,"down","yes"]
["chr7",99374658,99394795,"AC004922.1",13.42,0.49,0.04,-4.76,0,"down","yes"]
["chr11",128694092,128813267,"FLI1",13.66,0.54,0.04,-4.67,0,"down","yes"]
["chr9",114337207,114377532,"AKNA",7.4,0.29,0.04,-4.67,0,"down","yes"]
["chr4",75642782,75673969,"G3BP2",6.16,0.24,0.04,-4.68,0,"down","yes"]
["chr5",150401637,150412769,"CD74",212.44,8.85,0.04,-4.59,0,"down","yes"]
["chr4",88592423,88720331,"HERC3",9.23,0.38,0.04,-4.62,0,"down","yes"]
["chr14",21385486,21456080,"CHD8",2.32,0.09,0.04,-4.69,0,"down","yes"]
["chr5",17217560,17276834,"BASP1",99.76,4.19,0.04,-4.57,0,"down","yes"]
["chr12",53380639,53416446,"SP1",13.67,0.58,0.04,-4.57,0,"down","yes"]
["chr6",159679116,159693228,"SOD2",51.83,2.2,0.04,-4.56,0,"down","yes"]
["chr13",19958670,20091829,"ZMYM2",2.32,0.1,0.04,-4.55,0,"down","yes"]
["chr6",24804285,24910967,"RIPOR2",6.31,0.28,0.04,-4.52,0,"down","yes"]
["chr6",33291654,33299324,"RGL2",13.53,0.6,0.04,-4.49,0,"down","yes"]
["chrX",119786506,119791595,"RPL39",7.9,0.33,0.04,-4.58,0,"down","yes"]
["chr20",45891341,45898820,"CTSA",44.67,2.06,0.05,-4.44,0,"down","yes"]
["chr15",85544053,85749358,"AKAP13",2.93,0.13,0.04,-4.48,0,"down","yes"]
["chr10",128047570,128085855,"PTPRE",11.56,0.53,0.05,-4.45,0,"down","yes"]
["chr14",22946229,22957142,"HAUS4",10.04,0.43,0.04,-4.53,0,"down","yes"]
["chr11",309055,311138,"AC136475.2",11.74,0.52,0.04,-4.5,0,"down","yes"]
["chr2",219249711,219254608,"TUBA4A",7.91,0.36,0.05,-4.47,0,"down","yes"]
["chr6",73517521,73521721,"EEF1A1",919.51,45.04,0.05,-4.35,0,"down","yes"]
["chr1",12167003,12209228,"TNFRSF1B",16.45,0.79,0.05,-4.38,0,"down","yes"]
["chr12",57253777,57430807,"R3HDM2",6.39,0.3,0.05,-4.41,0,"down","yes"]
["chr1",154582067,154608198,"ADAR",9.04,0.44,0.05,-4.35,0,"down","yes"]
["chr1",161623990,161631206,"FCGR3B",385,19.46,0.05,-4.31,0,"down","yes"]
["chr6",73515750,73521018,"EEF1A1",123.35,6.33,0.05,-4.28,0,"down","yes"]
["chr2",159768630,159798255,"CD302",4.34,0.21,0.05,-4.39,0,"down","yes"]
["chr12",49208453,49273334,"TUBA1C",9.48,0.46,0.05,-4.37,0,"down","yes"]
["chr19",10625258,10644559,"SLC44A2",32.03,1.65,0.05,-4.27,0,"down","yes"]
["chr16",53450090,53491520,"RBL2",18.21,0.94,0.05,-4.28,0,"down","yes"]
["chr5",134115625,134148229,"TCF7",9.19,0.46,0.05,-4.33,0,"down","yes"]
["chr14",105736375,105864264,"IGHG1",11.08,0.56,0.05,-4.31,0,"down","yes"]
["chr11",64726911,64744834,"RASGRP2",24.88,1.29,0.05,-4.27,0,"down","yes"]
["chr12",6534534,6538359,"GAPDH",172.2,9.15,0.05,-4.23,0,"down","yes"]
["chr9",35104123,35115913,"FAM214B",10.03,0.51,0.05,-4.28,0,"down","yes"]
["chr2",181891985,181930738,"SSFA2",3.59,0.18,0.05,-4.32,0,"down","yes"]
["chr11",123057489,123062136,"HSPA8",13.47,0.7,0.05,-4.27,0,"down","yes"]
["chr19",19645203,19663693,"ATP13A1",7.74,0.41,0.05,-4.25,0,"down","yes"]
["chr14",22598237,22613215,"ABHD4",14.54,0.77,0.05,-4.23,0,"down","yes"]
["chr14",91114670,91225716,"C14orf159",6.9,0.36,0.05,-4.27,0,"down","yes"]
["chr14",103121431,103137439,"TNFAIP2",7.64,0.4,0.05,-4.25,0,"down","yes"]
["chr20",38472816,38578861,"RALGAPB",1.84,0.09,0.05,-4.28,0,"down","yes"]
["chr2",190180863,190203484,"C2orf88",11.42,0.62,0.05,-4.2,0,"down","yes"]
["chr15",85380715,85749355,"AKAP13",4.07,0.22,0.05,-4.19,0,"down","yes"]
["chr17",82228445,82239494,"SLC16A3",7.32,0.38,0.05,-4.28,0,"down","yes"]
["chr1",153728067,153774808,"INTS3",2.35,0.12,0.05,-4.3,0,"down","yes"]
["chr17",78112921,78127020,"TMC6",9.98,0.54,0.05,-4.22,0,"down","yes"]
["chr12",53038967,53047050,"AC068888.1",8.74,0.45,0.05,-4.27,0,"down","yes"]
["chr13",27620771,27667415,"POLR1D",10.07,0.55,0.05,-4.19,0,"down","yes"]
["chr16",15593901,15643060,"MARF1",18.33,1.05,0.06,-4.13,0,"down","yes"]
["chr8",47260955,47713441,"SPIDR",4.93,0.26,0.05,-4.22,0,"down","yes"]
["chr10",31319125,31529202,"ZEB1",2.81,0.15,0.05,-4.23,0,"down","yes"]
["chr15",98649044,98964529,"IGF1R",1.83,0.1,0.06,-4.17,0,"down","yes"]
["chr1",68098498,68232540,"WLS",13.71,0.78,0.06,-4.14,0,"down","yes"]
["chr1",27612589,27626135,"FGR",24.41,1.42,0.06,-4.1,0,"down","yes"]
["chr1",33323625,33349680,"PHC2",11.45,0.66,0.06,-4.13,0,"down","yes"]
["chr12",121237830,121296695,"CAMKK2",6.48,0.38,0.06,-4.11,0,"down","yes"]
["chr17",67077972,67245183,"HELZ",2.01,0.11,0.05,-4.19,0,"down","yes"]
["chr3",39263495,39281273,"CX3CR1",3.62,0.2,0.06,-4.17,0,"down","yes"]
["chr1",161541756,161550911,"FCGR3A",11.88,0.69,0.06,-4.1,0,"down","yes"]
["chr2",218382229,218395343,"SLC11A1",10.76,0.62,0.06,-4.11,0,"down","yes"]
["chr19",11300542,11339664,"RAB3D",17.32,1.05,0.06,-4.05,0,"down","yes"]
["chr9",35697337,35727764,"TLN1",60.08,3.69,0.06,-4.03,0,"down","yes"]
["chr15",55355250,55408510,"CCPG1",5.12,0.3,0.06,-4.07,0,"down","yes"]
["chr22",50274979,50307572,"PLXNB2",13.93,0.85,0.06,-4.03,0,"down","yes"]
["chr5",160401727,160417206,"SLU7",3.86,0.22,0.06,-4.13,0,"down","yes"]
["chr2",74526645,74529760,"AUP1",9.58,0.55,0.06,-4.14,0,"down","yes"]
["chr15",52307283,52529050,"MYO5A",2.25,0.14,0.06,-4.05,0,"down","yes"]
["chr2",181891955,181930738,"SSFA2",3.45,0.2,0.06,-4.09,0,"down","yes"]
["chr12",124324415,124535603,"NCOR2",3.52,0.22,0.06,-4.01,0,"down","yes"]
["chr15",81296913,81309083,"IL16",25.08,1.6,0.06,-3.97,0,"down","yes"]
["chr20",4780023,4823645,"RASSF2",22.52,1.46,0.07,-3.94,0,"down","yes"]
["chr19",18557788,18569378,"KXD1",17.81,1.12,0.06,-3.99,0,"down","yes"]
["chr12",6867420,6870946,"TPI1",31.02,2.02,0.07,-3.94,0,"down","yes"]
["chr16",30092314,30096200,"YPEL3",33.1,2.17,0.07,-3.93,0,"down","yes"]
["chr6",36885854,36928964,"C6orf89",1.48,0.09,0.06,-4.06,0,"down","yes"]
["chr10",103088017,103181329,"NT5C2",8.29,0.54,0.06,-3.95,0,"down","yes"]
["chr2",88027205,88055729,"KRCC1",11.99,0.77,0.06,-3.97,0,"down","yes"]
["chr1",159800523,159816424,"FCRL6",9.7,0.63,0.06,-3.95,0,"down","yes"]
["chr1",198156963,198322420,"NEK7",15.81,1.07,0.07,-3.89,0,"down","yes"]
["chr12",10212805,10223130,"GABARAPL1",28.89,1.96,0.07,-3.88,0,"down","yes"]
["chr12",122980748,122982706,"ARL6IP4",19.64,1.26,0.06,-3.96,0,"down","yes"]
["chr1",150621251,150629596,"ENSA",10.87,0.72,0.07,-3.92,0,"down","yes"]
["chr6",144659374,144852732,"UTRN",2.24,0.14,0.06,-3.96,0,"down","yes"]
["chr9",36336396,36400299,"RNF38",6.19,0.42,0.07,-3.89,0,"down","yes"]
["chr1",32013996,32042624,"KHDRBS1",11.87,0.77,0.07,-3.94,0,"down","yes"]
["chr19",17101718,17212099,"MYO9B",1.88,0.12,0.06,-3.95,0,"down","yes"]
["chr16",2088710,2135898,"PKD1",1.59,0.11,0.07,-3.86,0,"down","yes"]
["chr2",189661420,189670831,"ASNSD1",8.21,0.56,0.07,-3.87,0,"down","yes"]
["chr1",160995211,161021348,"F11R",5.65,0.39,0.07,-3.85,0,"down","yes"]
["chr19",54573792,54590287,"LILRA2",16.37,1.17,0.07,-3.81,0,"down","yes"]
["chr16",84565594,84618077,"COTL1",392.5,28.42,0.07,-3.79,0,"down","yes"]
["chr11",308121,309410,"IFITM2",13.18,0.9,0.07,-3.88,0,"down","yes"]
["chr19",7680843,7687703,"TRAPPC5",3.62,0.25,0.07,-3.85,0,"down","yes"]
["chr1",161624223,161631158,"FCGR3B",76.45,5.49,0.07,-3.8,0,"down","yes"]
["chr8",58553216,58582846,"SDCBP",11.3,0.79,0.07,-3.83,0,"down","yes"]
["chr2",190970117,191014211,"STAT1",18.46,1.33,0.07,-3.8,0,"down","yes"]
["chr8",11842524,11868229,"CTSB",82.19,6.08,0.07,-3.76,0,"down","yes"]
["chr19",11435288,11450965,"PRKCSH",13.18,0.94,0.07,-3.8,0,"down","yes"]
["chr1",155659443,155688656,"YY1AP1",3.37,0.23,0.07,-3.89,0,"down","yes"]
["chr7",2728112,2844324,"GNA12",7.5,0.54,0.07,-3.79,0,"down","yes"]
["chrX",44873177,45112598,"KDM6A",4.97,0.36,0.07,-3.8,0,"down","yes"]
["chr20",5544404,5611026,"GPCPD1",1.67,0.11,0.07,-3.88,0,"down","yes"]
["chrX",19533975,19887601,"SH3KBP1",30.75,2.3,0.07,-3.74,0,"down","yes"]
["chr10",97713724,97718152,"MARVELD1",4.29,0.3,0.07,-3.84,0,"down","yes"]
["chr7",75417503,75485976,"POM121C",13.36,1,0.07,-3.74,0,"down","yes"]
["chr2",117814650,117832379,"DDX18",3.82,0.27,0.07,-3.8,0,"down","yes"]
["chr3",100261012,100325238,"TBC1D23",2.75,0.19,0.07,-3.86,0,"down","yes"]
["chr1",226062678,226071999,"H3F3A",121.43,9.23,0.08,-3.72,0,"down","yes"]
["chr1",204516383,204558120,"MDM4",1.32,0.09,0.07,-3.8,0,"down","yes"]
["chr1",32936454,32964685,"RNF19B",11.51,0.86,0.07,-3.74,0,"down","yes"]
["chr3",57556277,57566844,"PDE12",1.2,0.09,0.07,-3.81,0,"down","yes"]
["chr5",172767136,172771251,"DUSP1",44.6,3.46,0.08,-3.69,0,"down","yes"]
["chr19",11300542,11339668,"RAB3D",9.78,0.75,0.08,-3.7,0,"down","yes"]
["chr6",151364117,151391548,"ZBTB2",4.65,0.34,0.07,-3.76,0,"down","yes"]
["chr11",59142748,59155039,"FAM111A",1.95,0.14,0.07,-3.78,0,"down","yes"]
["chr11",10573587,10606281,"MRVI1",17.52,1.36,0.08,-3.69,0,"down","yes"]
["chr12",6946577,6961316,"PTPN6",19.8,1.54,0.08,-3.69,0,"down","yes"]
["chr12",123383773,123409358,"KMT5A",2.76,0.2,0.07,-3.8,0,"down","yes"]
["chr16",28985096,28990773,"LAT",20.34,1.58,0.08,-3.69,0,"down","yes"]
["chr9",86264546,86282529,"ISCA1",15.01,1.17,0.08,-3.68,0,"down","yes"]
["chr11",67289348,67302483,"ANKRD13D",3.99,0.29,0.07,-3.76,0,"down","yes"]
["chr19",38409840,38426162,"RASGRP4",12.17,0.95,0.08,-3.68,0,"down","yes"]
["chr1",86704570,86748176,"SH3GLB1",4.98,0.39,0.08,-3.68,0,"down","yes"]
["chr14",39267411,39350421,"CTAGE5",3.38,0.25,0.07,-3.78,0,"down","yes"]
["chr8",30063012,30083208,"SARAF",25.96,2.08,0.08,-3.64,0,"down","yes"]
["chr2",74526648,74529939,"AUP1",10.13,0.78,0.08,-3.7,0,"down","yes"]
["chr11",85957559,86068871,"PICALM",44.41,3.63,0.08,-3.61,0,"down","yes"]
["chr18",9546791,9614569,"PPP4R1",5.44,0.43,0.08,-3.67,0,"down","yes"]
["chr12",10699555,10723338,"YBX3",25.73,2.06,0.08,-3.64,0,"down","yes"]
["chr1",1663782,1670139,"SLC35E2B",2.97,0.22,0.08,-3.73,0,"down","yes"]
["chr20",47657406,47786616,"SULF2",14.42,1.17,0.08,-3.62,0,"down","yes"]
["chr1",151291797,151327715,"PI4KB",2.45,0.18,0.07,-3.74,0,"down","yes"]
["chr11",104942868,104956698,"CASP4",6.42,0.49,0.08,-3.71,0,"down","yes"]
["chr10",124007668,124092454,"CHST15",11.71,0.96,0.08,-3.61,0,"down","yes"]
["chr21",25881610,26170667,"APP",11.09,0.9,0.08,-3.63,0,"down","yes"]
["chr12",31958570,31993082,"KIAA1551",13.14,1.09,0.08,-3.59,0,"down","yes"]
["chr19",48325581,48330553,"EMP3",23.19,1.85,0.08,-3.64,0,"down","yes"]
["chr6",89080713,89084839,"PNRC1",92.19,7.72,0.08,-3.58,0,"down","yes"]
["chr20",23633648,23638026,"CST3",69.02,5.73,0.08,-3.59,0,"down","yes"]
["chr11",47465979,47553145,"CELF1",5.36,0.44,0.08,-3.6,0,"down","yes"]
["chr12",57694132,57721559,"OS9",8.61,0.7,0.08,-3.62,0,"down","yes"]
["chr10",124007666,124093607,"CHST15",12.55,1.05,0.08,-3.58,0,"down","yes"]
["chr13",112690329,112887168,"ATP11A",3.91,0.33,0.08,-3.58,0,"down","yes"]
["chr5",160251652,160312600,"CCNJL",6.21,0.51,0.08,-3.6,0,"down","yes"]
["chr15",50424382,50499776,"USP8",2.31,0.18,0.08,-3.66,0,"down","yes"]
["chr9",34179038,34252520,"UBAP1",4.51,0.37,0.08,-3.62,0,"down","yes"]
["chr19",35154747,35169782,"FXYD5",22.72,1.91,0.08,-3.58,0,"down","yes"]
["chr10",17229278,17237593,"VIM",7.74,0.64,0.08,-3.59,0,"down","yes"]
["chr8",8317736,8381747,"PRAG1",2.01,0.16,0.08,-3.63,0,"down","yes"]
["chr4",42408377,42657093,"ATP8A1",1.38,0.11,0.08,-3.6,0,"down","yes"]
["chr3",155080399,155180488,"MME",13.58,1.17,0.09,-3.54,0,"down","yes"]
["chr1",207752068,207795513,"CD46",5.59,0.48,0.09,-3.53,0,"down","yes"]
["chr6",26440476,26453411,"BTN3A3",4.52,0.38,0.08,-3.58,0,"down","yes"]
["chr11",46617552,46673105,"ATG13",15.28,1.33,0.09,-3.52,0,"down","yes"]
["chr10",5765954,5813411,"GDI2",43.47,3.83,0.09,-3.5,0,"down","yes"]
["chrX",24149724,24216255,"ZFX",1,0.08,0.08,-3.62,0,"down","yes"]
["chr22",37226673,37244432,"RAC2",16.04,1.37,0.09,-3.55,0,"down","yes"]
["chr1",24899518,24929877,"RUNX3",28.61,2.57,0.09,-3.48,0,"down","yes"]
["chr8",58411264,58451501,"UBXN2B",3.04,0.26,0.09,-3.54,0,"down","yes"]
["chr22",42869775,42959881,"PACSIN2",4.46,0.39,0.09,-3.53,0,"down","yes"]
["chr1",159009892,159055155,"IFI16",2.96,0.25,0.08,-3.59,0,"down","yes"]
["chr3",12836050,12841545,"RPL32",111.59,10.19,0.09,-3.45,0,"down","yes"]
["chr15",25333728,25439037,"UBE3A",1.28,0.11,0.09,-3.52,0,"down","yes"]
["chr14",24429938,24438408,"KHNYN",4.41,0.39,0.09,-3.49,0,"down","yes"]
["chr4",139057855,139084496,"ELF2",3.16,0.27,0.09,-3.53,0,"down","yes"]
["chr19",2037604,2050915,"MKNK2",45.85,4.3,0.09,-3.41,0,"down","yes"]
["chr20",34704290,34713439,"TP53INP2",8.56,0.79,0.09,-3.43,0,"down","yes"]
["chr9",137030174,137033010,"FUT7",10.49,0.98,0.09,-3.42,0,"down","yes"]
["chr1",149844498,149849024,"AC239868.2",2.35,0.21,0.09,-3.48,0,"down","yes"]
["chr5",157266096,157395596,"CYFIP2",7.08,0.67,0.09,-3.41,0,"down","yes"]
["chr19",16517896,16542415,"CHERP",2.26,0.2,0.09,-3.51,0,"down","yes"]
["chrX",96685017,97469765,"DIAPH2",2.3,0.2,0.09,-3.53,0,"down","yes"]
["chr7",36854462,36985060,"ELMO1",5.47,0.49,0.09,-3.49,0,"down","yes"]
["chr16",57668187,57689378,"ADGRG3",35.02,3.35,0.1,-3.38,0,"down","yes"]
["chr21",33543049,33577482,"SON",11,1.05,0.1,-3.38,0,"down","yes"]
["chr10",28533419,28620543,"WAC",32.7,3.15,0.1,-3.38,0,"down","yes"]
["chr8",58553169,58582860,"SDCBP",53.97,5.22,0.1,-3.37,0,"down","yes"]
["chr2",8728409,8837613,"KIDINS220",9.65,0.93,0.1,-3.38,0,"down","yes"]
["chr2",68774801,68826833,"ARHGAP25",9.75,0.93,0.1,-3.38,0,"down","yes"]
["chr5",177301198,177303733,"RAB24",13.53,1.3,0.1,-3.38,0,"down","yes"]
["chr6",41267552,41286727,"TREM1",10.95,1.02,0.09,-3.42,0,"down","yes"]
["chr19",10718079,10831047,"DNM2",10.39,1,0.1,-3.38,0,"down","yes"]
["chr8",47773735,47960178,"PRKDC",3.76,0.37,0.1,-3.36,0,"down","yes"]
["chr11",118193963,118213359,"JAML",9.83,0.94,0.1,-3.39,0,"down","yes"]
["chr2",216498867,216501467,"RPL37A",20.24,1.91,0.09,-3.4,0,"down","yes"]
["chr17",7219806,7225273,"ACADVL",10.53,1.01,0.1,-3.38,0,"down","yes"]
["chr15",94298266,94479034,"MCTP2",7.03,0.67,0.1,-3.39,0,"down","yes"]
["chr3",9793095,9804214,"ARPC4",10.27,0.93,0.09,-3.47,0,"down","yes"]
["chr3",125225561,125375354,"ZNF148",2.94,0.29,0.1,-3.36,0,"down","yes"]
["chr7",128027071,128031070,"LRRC4",13.47,1.33,0.1,-3.34,0,"down","yes"]
["chr15",66500949,66504846,"RPL4",43.52,4.27,0.1,-3.35,0,"down","yes"]
["chr12",49644953,49707393,"FMNL3",3.54,0.34,0.1,-3.39,0,"down","yes"]
["chr7",66114605,66154561,"CRCP",5.54,0.53,0.1,-3.38,0,"down","yes"]
["chr2",85584408,85593412,"VAMP5",12.82,1.19,0.09,-3.43,0,"down","yes"]
["chr1",70205682,70251617,"SRSF11",2.91,0.26,0.09,-3.46,0,"down","yes"]
["chr6",42928680,42941142,"CNPY3",31.13,3.13,0.1,-3.32,0,"down","yes"]
["chr3",45689262,45745424,"SACM1L",6.07,0.6,0.1,-3.35,0,"down","yes"]
["chr12",112978395,113011723,"OAS2",5.18,0.51,0.1,-3.35,0,"down","yes"]
["chr19",13144089,13150238,"STX10",24.52,2.42,0.1,-3.34,0,"down","yes"]
["chr1",89821032,89936611,"LRRC8D",1.74,0.16,0.09,-3.42,0,"down","yes"]
["chr20",49903391,49915508,"SPATA2",2.48,0.24,0.1,-3.39,0,"down","yes"]
["chr1",151254709,151267459,"PSMD4",17.78,1.78,0.1,-3.32,0,"down","yes"]
["chr5",172767136,172771251,"DUSP1",35.69,3.67,0.1,-3.28,0,"down","yes"]
["chr1",155659446,155688573,"YY1AP1",3.06,0.29,0.1,-3.39,0,"down","yes"]
["chr4",6707701,6709827,"MRFAP1L1",12.72,1.28,0.1,-3.31,0,"down","yes"]
["chr2",216499086,216501463,"RPL37A",46,4.61,0.1,-3.32,0,"down","yes"]
["chr3",38138644,38143022,"MYD88",27.55,2.83,0.1,-3.28,0,"down","yes"]
["chr6",16129171,16148248,"MYLIP",6.96,0.7,0.1,-3.32,0,"down","yes"]
["chr1",36393430,36397892,"LSM10",11.57,1.13,0.1,-3.35,0,"down","yes"]
["chr20",49886371,49892242,"SLC9A8",3.32,0.33,0.1,-3.32,0,"down","yes"]
["chr12",752576,912051,"WNK1",6.28,0.65,0.1,-3.28,0,"down","yes"]
["chr2",159768853,159798242,"CD302",6.5,0.66,0.1,-3.3,0,"down","yes"]
["chr16",1773326,1780627,"EME2",1.36,0.13,0.1,-3.36,0,"down","yes"]
["chr15",63189603,63263596,"RAB8B",12.62,1.25,0.1,-3.34,0,"down","yes"]
["chrX",154348784,154371288,"FLNA",11.99,1.26,0.11,-3.25,0,"down","yes"]
["chr5",157180843,157255099,"ITK",3.26,0.33,0.1,-3.29,0,"down","yes"]
["chr14",35401540,35404746,"NFKBIA",5.17,0.5,0.1,-3.37,0,"down","yes"]
["chr12",752576,912051,"WNK1",5.31,0.56,0.11,-3.25,0,"down","yes"]
["chr17",50719613,50750952,"LUC7L3",9.38,0.97,0.1,-3.28,0,"down","yes"]
["chr12",57472264,57479632,"ARHGAP9",8.69,0.9,0.1,-3.26,0,"down","yes"]
["chr7",44072256,44082511,"POLM",2.17,0.21,0.1,-3.39,0,"down","yes"]
["chr12",10372353,10390018,"KLRK1",6.56,0.65,0.1,-3.33,0,"down","yes"]
["chr15",55359018,55408052,"CCPG1",7.86,0.82,0.1,-3.26,0,"down","yes"]
["chr20",37694006,37872129,"CTNNBL1",3.44,0.34,0.1,-3.35,0,"down","yes"]
["chr14",69653237,69714449,"SUSD6",20.48,2.2,0.11,-3.22,0,"down","yes"]
["chr22",20085822,20111872,"DGCR8",2.41,0.24,0.1,-3.3,0,"down","yes"]
["chr19",14381444,14408721,"ADGRE5",112.03,12.16,0.11,-3.2,0,"down","yes"]
["chr7",66628767,66644015,"KCTD7",2.4,0.25,0.1,-3.26,0,"down","yes"]
["chr22",42583721,42614931,"POLDIP3",3.4,0.35,0.1,-3.29,0,"down","yes"]
["chr8",129841697,130016543,"FAM49B",29.81,3.21,0.11,-3.22,0,"down","yes"]
["chr16",18781295,18790334,"RPS15A",63.68,6.93,0.11,-3.2,0,"down","yes"]
["chr1",207752057,207795513,"CD46",3.71,0.38,0.1,-3.27,0,"down","yes"]
["chr5",140632344,140633651,"CD14",8.84,0.9,0.1,-3.3,0,"down","yes"]
["chr5",75337232,75361423,"HMGCR",6.35,0.68,0.11,-3.22,0,"down","yes"]
["chr12",57755098,57760407,"9-Mar",3.48,0.36,0.1,-3.27,0,"down","yes"]
["chr17",75845709,75855322,"WBP2",15.31,1.65,0.11,-3.21,0,"down","yes"]
["chr6",99401461,99425308,"PNISR",14.73,1.59,0.11,-3.21,0,"down","yes"]
["chr19",15421523,15433290,"WIZ",2.24,0.23,0.1,-3.26,0,"down","yes"]
["chr16",47461295,47699745,"PHKB",2.89,0.3,0.1,-3.26,0,"down","yes"]
["chr22",22409751,22906779,"IGLV1-40",11.12,1.15,0.1,-3.27,0,"down","yes"]
["chr17",40122614,40134450,"MSL1",11.81,1.26,0.11,-3.22,0,"down","yes"]
["chr2",71407239,71435060,"ZNF638",2.79,0.29,0.11,-3.25,0,"down","yes"]
["chr20",408053,430966,"RBCK1",3.79,0.4,0.1,-3.26,0,"down","yes"]
["chr1",175156987,175192793,"KIAA0040",16.58,1.84,0.11,-3.18,0,"down","yes"]
["chr9",97600083,97633575,"TSTD2",1.94,0.2,0.1,-3.27,0,"down","yes"]
["chr1",1785286,1848029,"GNB1",7.32,0.79,0.11,-3.21,0,"down","yes"]
["chr6",73517519,73520059,"EEF1A1",173.09,19.4,0.11,-3.16,0,"down","yes"]
["chr16",68085658,68229259,"NFATC3",12.95,1.44,0.11,-3.16,0,"down","yes"]
["chr3",52246209,52250597,"PPM1M",7.55,0.81,0.11,-3.21,0,"down","yes"]
["chrX",9465008,9719743,"TBL1X",5.09,0.56,0.11,-3.17,0,"down","yes"]
["chr10",69057566,69104818,"SRGN",122.32,13.83,0.11,-3.15,0,"down","yes"]
["chr12",111642146,111685986,"BRAP",3.96,0.43,0.11,-3.2,0,"down","yes"]
["chr1",45627306,45686630,"GPBP1L1",7.82,0.87,0.11,-3.17,0,"down","yes"]
["chr1",109309570,109397951,"SORT1",6.24,0.7,0.11,-3.15,0,"down","yes"]
["chr12",108288044,108339317,"CMKLR1",2.37,0.26,0.11,-3.19,0,"down","yes"]
["chr1",23310333,23344295,"HNRNPR",9.23,1.03,0.11,-3.17,0,"down","yes"]
["chr10",69087280,69104818,"SRGN",100.03,11.48,0.11,-3.12,0,"down","yes"]
["chr7",26189927,26201243,"HNRNPA2B1",26.43,3.03,0.11,-3.12,0,"down","yes"]
["chr12",6951262,6961316,"PTPN6",5.78,0.63,0.11,-3.2,0,"down","yes"]
["chr2",120252805,120293665,"RALB",12.8,1.42,0.11,-3.17,0,"down","yes"]
["chr1",150574551,150579738,"MCL1",7.51,0.85,0.11,-3.15,0,"down","yes"]
["chr6",33318559,33323016,"DAXX",4.18,0.46,0.11,-3.19,0,"down","yes"]
["chr12",51238724,51243931,"DAZAP2",15.45,1.75,0.11,-3.14,0,"down","yes"]
["chr6",134169881,134177905,"SGK1",4.14,0.44,0.11,-3.22,0,"down","yes"]
["chr19",2511219,2702709,"GNG7",3.33,0.37,0.11,-3.17,0,"down","yes"]
["chr10",103088060,103181329,"NT5C2",2.81,0.31,0.11,-3.19,0,"down","yes"]
["chr19",34428352,34471318,"UBA2",1.7,0.18,0.11,-3.23,0,"down","yes"]
["chr2",113173997,113209396,"PSD4",5.2,0.6,0.11,-3.12,0,"down","yes"]
["chr1",175945153,176206978,"RFWD2",11.35,1.29,0.11,-3.14,0,"down","yes"]
["chr9",89377977,89479883,"SEMA4D",32.96,3.84,0.12,-3.1,0,"down","yes"]
["chr11",65096227,65108399,"VPS51",10.17,1.12,0.11,-3.19,0,"down","yes"]
["chr11",5225461,5234472,"HBB",2580.92,301.82,0.12,-3.1,0,"down","yes"]
["chr1",36466096,36479519,"CSF3R",22.95,2.66,0.12,-3.11,0,"down","yes"]
["chr14",99481407,99510311,"CCNK",9.42,1.06,0.11,-3.15,0,"down","yes"]
["chr1",244850297,244864560,"HNRNPU",9.88,1.15,0.12,-3.1,0,"down","yes"]
["chr20",408065,430964,"RBCK1",2.59,0.28,0.11,-3.2,0,"down","yes"]
["chr12",76047155,76084666,"NAP1L1",39.13,4.6,0.12,-3.09,0,"down","yes"]
["chr1",11785723,11805413,"MTHFR",1,0.11,0.11,-3.18,0,"down","yes"]
["chr1",42456559,42460414,"PPCS",13.13,1.51,0.12,-3.12,0,"down","yes"]
["chr11",313506,315272,"IFITM1",15.84,1.78,0.11,-3.15,0,"down","yes"]
["chr19",1031137,1038309,"CNN2",7.01,0.79,0.11,-3.16,0,"down","yes"]
["chr6",15246296,15522021,"JARID2",11.83,1.4,0.12,-3.08,0,"down","yes"]
["chr8",23102590,23117437,"TNFRSF10C",149.56,17.82,0.12,-3.07,0,"down","yes"]
["chr1",155051286,155062758,"ADAM15",2.69,0.3,0.11,-3.18,0,"down","yes"]
["chr12",89588072,89708831,"ATP2B1",3.95,0.46,0.12,-3.09,0,"down","yes"]
["chr7",74209981,74226508,"LAT2",6.71,0.78,0.12,-3.1,0,"down","yes"]
["chr5",143281162,143403689,"NR3C1",2.48,0.28,0.11,-3.14,0,"down","yes"]
["chr3",37988059,38007188,"VILL",2.3,0.26,0.11,-3.15,0,"down","yes"]
["chr11",6395125,6419414,"APBB1",2.23,0.25,0.11,-3.16,0,"down","yes"]
["chr15",91853695,92165903,"SLCO3A1",7.74,0.92,0.12,-3.06,0,"down","yes"]
["chr19",1026629,1039068,"CNN2",27.8,3.34,0.12,-3.06,0,"down","yes"]
["chr11",114400529,114408924,"RBM7",3.63,0.41,0.11,-3.15,0,"down","yes"]
["chr16",89707134,89720986,"VPS9D1",2.4,0.27,0.11,-3.14,0,"down","yes"]
["chr4",2938113,2963333,"NOP14",2.25,0.25,0.11,-3.17,0,"down","yes"]
["chr20",37346154,37406050,"SRC",4.43,0.53,0.12,-3.07,0,"down","yes"]
["chr12",110491894,110502118,"VPS29",20.68,2.45,0.12,-3.08,0,"down","yes"]
["chr15",41517176,41544259,"RPAP1",1.57,0.18,0.11,-3.14,0,"down","yes"]
["chr19",1026610,1039068,"CNN2",8.58,1.02,0.12,-3.07,0,"down","yes"]
["chr9",36136742,36162910,"GLIPR2",36.04,4.36,0.12,-3.05,0,"down","yes"]
["chr16",30699141,30741409,"SRCAP",2.77,0.34,0.12,-3.04,0,"down","yes"]
["chr1",27234516,27308633,"WDTC1",14.58,1.8,0.12,-3.02,0,"down","yes"]
["chr3",9793082,9806436,"ARPC4",7.71,0.89,0.12,-3.11,0,"down","yes"]
["chr11",3675010,3797792,"NUP98",10.9,1.35,0.12,-3.01,0,"down","yes"]
["chr19",54449103,54462037,"LENG8",2.72,0.33,0.12,-3.04,0,"down","yes"]
["chr1",207752057,207795513,"CD46",3.26,0.39,0.12,-3.06,0,"down","yes"]
["chr18",63969925,63989374,"SERPINB8",3.16,0.38,0.12,-3.06,0,"down","yes"]
["chr9",69174165,69255204,"TJP2",3.24,0.4,0.12,-3.04,0,"down","yes"]
["chr6",31530219,31542448,"DDX39B",8.67,1.06,0.12,-3.03,0,"down","yes"]
["chr8",58559892,58582889,"SDCBP",21.21,2.67,0.13,-2.99,0,"down","yes"]
["chr12",89347232,89353271,"DUSP6",43.12,5.47,0.13,-2.98,0,"down","yes"]
["chr3",58008400,58170774,"FLNB",1.11,0.14,0.12,-3.04,0,"down","yes"]
["chrX",108091668,108154671,"ATG4A",2.84,0.34,0.12,-3.08,0,"down","yes"]
["chr6",159682165,159693278,"SOD2",112.58,14.39,0.13,-2.97,0,"down","yes"]
["chr19",54191253,54193666,"TSEN34",25.97,3.32,0.13,-2.97,0,"down","yes"]
["chr17",56887909,56914038,"TRIM25",7.38,0.95,0.13,-2.97,0,"down","yes"]
["chr1",207496228,207640208,"CR1",2.86,0.36,0.13,-2.98,0,"down","yes"]
["chr15",76216250,76311448,"ETFA",4.42,0.52,0.12,-3.08,0,"down","yes"]
["chr17",49598884,49678110,"SPOP",2.09,0.25,0.12,-3.06,0,"down","yes"]
["chr12",6638075,6639278,"ACRBP",11.68,1.44,0.12,-3.02,0,"down","yes"]
["chr10",17228259,17237592,"VIM",68.1,8.91,0.13,-2.93,0,"down","yes"]
["chr1",204516379,204558119,"MDM4",1.31,0.17,0.13,-2.98,0,"down","yes"]
["chr12",6452084,6462318,"TAPBPL",3.76,0.46,0.12,-3.02,0,"down","yes"]
["chr12",57472259,57477927,"ARHGAP9",11.82,1.53,0.13,-2.95,0,"down","yes"]
["chr21",42219118,42297244,"ABCG1",4.79,0.61,0.13,-2.97,0,"down","yes"]
["chr2",174559574,174682957,"WIPF1",32.1,4.24,0.13,-2.92,0,"down","yes"]
["chrX",66015194,66020422,"AL034397.3",11.98,1.55,0.13,-2.95,0,"down","yes"]
["chr8",20197367,20221701,"ATP6V1B2",49.11,6.5,0.13,-2.92,0,"down","yes"]
["chr12",105173296,105236238,"APPL2",4.65,0.6,0.13,-2.96,0,"down","yes"]
["chr12",6951356,6961316,"PTPN6",6.41,0.83,0.13,-2.95,0,"down","yes"]
["chr16",50287912,50318132,"ADCY7",6.59,0.87,0.13,-2.92,0,"down","yes"]
["chr19",52154848,52171491,"ZNF836",1.62,0.2,0.12,-3.03,0,"down","yes"]
["chr7",106248285,106285192,"NAMPT",59.49,7.97,0.13,-2.9,0,"down","yes"]
["chr5",176905005,177006408,"UIMC1",3.98,0.51,0.13,-2.96,0,"down","yes"]
["chr1",36156202,36180840,"MAP7D1",8.28,1.09,0.13,-2.92,0,"down","yes"]
["chr5",132891817,132963618,"AFF4",1.48,0.18,0.12,-3.03,0,"down","yes"]
["chr1",45551067,45570049,"AKR1A1",7.28,0.93,0.13,-2.97,0,"down","yes"]
["chr17",44345166,44353106,"GRN",20.33,2.73,0.13,-2.9,0,"down","yes"]
["chr17",63695902,63700140,"LIMD2",13.81,1.86,0.13,-2.9,0,"down","yes"]
["chr1",20807004,21176847,"EIF4G3",3.64,0.49,0.13,-2.91,0,"down","yes"]
["chr10",97356701,97373593,"RRP12",6.02,0.8,0.13,-2.91,0,"down","yes"]
["chr12",49002281,49060107,"KMT2D",4.64,0.63,0.14,-2.87,0,"down","yes"]
["chr1",33256545,33299353,"ZNF362",9.03,1.2,0.13,-2.91,0,"down","yes"]
["chr4",102795976,102828159,"UBE2D3",14.34,1.94,0.14,-2.89,0,"down","yes"]
["chr16",29806088,29811164,"MAZ",7.18,0.96,0.13,-2.9,0,"down","yes"]
["chr22",31281613,31292534,"PIK3IP1",2.71,0.34,0.13,-2.98,0,"down","yes"]
["chr3",119468938,119494708,"POGLUT1",1.82,0.23,0.13,-2.98,0,"down","yes"]
["chr4",2468937,2515855,"RNF4",25.18,3.47,0.14,-2.86,0,"down","yes"]
["chr12",112160190,112382439,"HECTD4",2.07,0.28,0.14,-2.87,0,"down","yes"]
["chr6",33304268,33314041,"TAPBP",21.35,2.91,0.14,-2.88,0,"down","yes"]
["chr8",67197649,67343677,"ARFGEF1",1.73,0.23,0.13,-2.9,0,"down","yes"]
["chr11",65775893,65780802,"AP5B1",13.13,1.82,0.14,-2.85,0,"down","yes"]
["chr17",77451244,77499024,"9-Sep",81.01,11.31,0.14,-2.84,0,"down","yes"]
["chrX",154487306,154490690,"SLC10A3",2.58,0.33,0.13,-2.97,0,"down","yes"]
["chr1",26696404,26780817,"ARID1A",3.59,0.49,0.14,-2.86,0,"down","yes"]
["chr14",94378373,94388847,"SERPINA1",20.57,2.85,0.14,-2.85,0,"down","yes"]
["chr20",53567073,53609847,"ZNF217",7.63,1.07,0.14,-2.84,0,"down","yes"]
["chr19",54217120,54220790,"LILRB3",14.51,1.97,0.14,-2.88,0,"down","yes"]
["chr16",67541347,67546786,"RIPOR1",2.34,0.31,0.13,-2.92,0,"down","yes"]
["chr4",153684275,153709588,"TLR2",12.41,1.75,0.14,-2.82,0,"down","yes"]
["chr19",54200742,54207647,"RPS9",54.65,7.68,0.14,-2.83,0,"down","yes"]
["chr1",16367083,16398142,"SZRD1",4.28,0.59,0.14,-2.86,0,"down","yes"]
["chr1",175012958,175023425,"MRPS14",2.94,0.39,0.13,-2.92,0,"down","yes"]
["chr4",39454124,39458925,"RPL9",46.41,6.53,0.14,-2.83,0,"down","yes"]
["chr12",109999537,110039432,"ANKRD13A",9.18,1.29,0.14,-2.83,0,"down","yes"]
["chr21",33718810,33817614,"ITSN1",1.54,0.2,0.13,-2.95,0,"down","yes"]
["chrX",153947559,153971184,"HCFC1",2.22,0.31,0.14,-2.84,0,"down","yes"]
["chr1",161505451,161596728,"FCGR2A",4.75,0.65,0.14,-2.87,0,"down","yes"]
["chr11",65576046,65585417,"EHBP1L1",2.5,0.33,0.13,-2.92,0,"down","yes"]
["chr2",24584541,24770702,"NCOA1",10.65,1.52,0.14,-2.81,0,"down","yes"]
["chr2",231708509,231713541,"PTMA",121.95,17.53,0.14,-2.8,0,"down","yes"]
["chr15",34233259,34337786,"SLC12A6",1.17,0.16,0.13,-2.9,0,"down","yes"]
["chr15",90915995,90919689,"MAN2A2",17.87,2.51,0.14,-2.83,0,"down","yes"]
["chr22",30881681,30907623,"OSBP2",8.65,1.24,0.14,-2.81,0,"down","yes"]
["chr11",62676613,62679081,"UBXN1",5.58,0.75,0.13,-2.9,0,"down","yes"]
["chr9",34179005,34251850,"UBAP1",11.63,1.66,0.14,-2.81,0,"down","yes"]
["chr2",218382229,218395343,"SLC11A1",15.88,2.3,0.14,-2.79,0,"down","yes"]
["chr5",151030581,151081074,"TNIP1",13.42,1.93,0.14,-2.8,0,"down","yes"]
["chr11",130069886,130144806,"APLP2",7.71,1.11,0.14,-2.8,0,"down","yes"]
["chr5",38940020,39074399,"RICTOR",3.71,0.53,0.14,-2.79,0,"down","yes"]
["chrX",41688973,41697277,"GPR34",2.71,0.36,0.13,-2.9,0,"down","yes"]
["chr3",49171611,49176486,"KLHDC8B",2.7,0.36,0.13,-2.9,0,"down","yes"]
["chr14",64746283,64879883,"SPTB",2.69,0.39,0.14,-2.79,0,"down","yes"]
["chr4",176319964,176332245,"SPCS3",8.57,1.25,0.15,-2.78,0,"down","yes"]
["chr16",19501689,19522145,"GDE1",15.32,2.23,0.15,-2.78,0,"down","yes"]
["chr1",46607725,46616465,"MOB3C",1.47,0.21,0.14,-2.84,0,"down","yes"]
["chr7",106277056,106285612,"NAMPT",44.21,6.32,0.14,-2.81,0,"down","yes"]
["chr2",201260538,201287495,"CASP8",31.09,4.56,0.15,-2.77,0,"down","yes"]
["chr12",8914741,8939935,"PHC1",1.58,0.22,0.14,-2.85,0,"down","yes"]
["chr8",119416306,119424353,"NOV",8.43,1.23,0.15,-2.78,0,"down","yes"]
["chr14",102139844,102223673,"WDR20",2.45,0.34,0.14,-2.85,0,"down","yes"]
["chr1",247297412,247331743,"ZNF496",1.62,0.23,0.14,-2.81,0,"down","yes"]
["chr1",155002657,155018522,"ZBTB7B",16.08,2.39,0.15,-2.75,0,"down","yes"]
["chr6",31586179,31588909,"LST1",8.46,1.18,0.14,-2.84,0,"down","yes"]
["chr22",19036283,19122445,"DGCR2",12.33,1.84,0.15,-2.75,0,"down","yes"]
["chr12",56116586,56117943,"RPL41",211.1,31.73,0.15,-2.73,0,"down","yes"]
["chr11",65120630,65122057,"FAU",7.97,1.11,0.14,-2.85,0,"down","yes"]
["chr6",36291390,36312229,"PNPLA1",2.58,0.35,0.14,-2.86,0,"down","yes"]
["chr5",172768090,172771195,"DUSP1",41.3,6.22,0.15,-2.73,0,"down","yes"]
["chr16",70113626,70162537,"PDPR",1.41,0.21,0.15,-2.77,0,"down","yes"]
["chr17",42189089,42194484,"GHDC",2.63,0.37,0.14,-2.82,0,"down","yes"]
["chr19",11574660,11578985,"ACP5",6.85,1,0.15,-2.78,0,"down","yes"]
["chr6",31639028,31652393,"BAG6",30.48,4.61,0.15,-2.73,0,"down","yes"]
["chr7",106269155,106284632,"NAMPT",13.37,1.95,0.15,-2.78,0,"down","yes"]
["chr11",73376264,73397472,"RELT",2.66,0.39,0.15,-2.78,0,"down","yes"]
["chr19",51752002,51771299,"FPR2",11.42,1.72,0.15,-2.73,0,"down","yes"]
["chrX",20150562,20266721,"RPS6KA3",7.28,1.09,0.15,-2.74,0,"down","yes"]
["chr11",112024814,112064390,"DLAT",2.78,0.41,0.15,-2.76,0,"down","yes"]
["chr10",100981376,100987494,"MRPL43",9.46,1.37,0.14,-2.79,0,"down","yes"]
["chr17",5499521,5619424,"NLRP1",2.22,0.33,0.15,-2.74,0,"down","yes"]
["chr1",207496268,207639409,"CR1",6.81,1.04,0.15,-2.71,0,"down","yes"]
["chr1",27612589,27635200,"FGR",19.69,3.02,0.15,-2.7,0,"down","yes"]
["chr2",130338241,130342349,"CCDC115",11.39,1.72,0.15,-2.72,0,"down","yes"]
["chr1",23743366,23762040,"ELOA",1.31,0.19,0.15,-2.78,0,"down","yes"]
["chr14",103126389,103135651,"TNFAIP2",15.76,2.41,0.15,-2.71,0,"down","yes"]
["chr3",127672958,127680920,"ABTB1",20.64,3.17,0.15,-2.7,0,"down","yes"]
["chr1",11654901,11663326,"FBXO44",2.2,0.32,0.15,-2.78,0,"down","yes"]
["chr19",896504,913245,"R3HDM4",8.19,1.24,0.15,-2.72,0,"down","yes"]
["chr17",40122298,40136916,"MSL1",7.11,1.1,0.15,-2.7,0,"down","yes"]
["chr20",56412261,56460387,"CASS4",5.14,0.78,0.15,-2.72,0,"down","yes"]
["chr11",47572198,47578789,"KBTBD4",1.56,0.22,0.14,-2.8,0,"down","yes"]
["chr16",28974772,28984548,"SPNS1",6.04,0.91,0.15,-2.73,0,"down","yes"]
["chr6",43037620,43053945,"CUL7",1.29,0.19,0.15,-2.76,0,"down","yes"]
["chr1",151050973,151059649,"CDC42SE1",70.43,11.02,0.16,-2.68,0,"down","yes"]
["chr11",73974852,73978141,"UCP2",5.61,0.82,0.15,-2.78,0,"down","yes"]
["chr3",46979810,47009703,"NBEAL2",17.14,2.69,0.16,-2.67,0,"down","yes"]
["chr7",112423144,112475527,"IFRD1",10.8,1.66,0.15,-2.7,0,"down","yes"]
["chr16",18782968,18790362,"RPS15A",80.9,12.63,0.16,-2.68,0,"down","yes"]
["chr2",69789545,69798998,"ANXA4",5.78,0.86,0.15,-2.75,0,"down","yes"]
["chr13",45333471,45341284,"TPT1",1.2,0.17,0.14,-2.79,0,"down","yes"]
["chr16",50693591,50734248,"NOD2",8.92,1.39,0.16,-2.68,0,"down","yes"]
["chr12",108778192,108857590,"SSH1",3.59,0.56,0.16,-2.68,0,"down","yes"]
["chr6",85608329,85642991,"SYNCRIP",3.3,0.51,0.16,-2.69,0,"down","yes"]
["chr7",99325879,99394653,"AC004922.1",2.49,0.37,0.15,-2.76,0,"down","yes"]
["chr13",113490995,113550195,"TMCO3",7.28,1.13,0.16,-2.69,0,"down","yes"]
["chr1",16367265,16398142,"SZRD1",8.84,1.39,0.16,-2.67,0,"down","yes"]
["chr1",66924959,66985684,"MIER1",2.84,0.43,0.15,-2.72,0,"down","yes"]
["chr7",115935148,116030741,"TFEC",1.22,0.19,0.15,-2.71,0,"down","yes"]
["chrX",30834621,30871802,"TAB3",1.7,0.26,0.16,-2.68,0,"down","yes"]
["chr8",30063012,30083207,"SARAF",44.46,7.11,0.16,-2.64,0,"down","yes"]
["chrX",139726349,139832288,"ATP11C",1.14,0.17,0.15,-2.72,0,"down","yes"]
["chr1",11980312,12013508,"MFN2",4.74,0.75,0.16,-2.66,0,"down","yes"]
["chr3",52455508,52493071,"NISCH",6.3,1,0.16,-2.65,0,"down","yes"]
["chr6",89329659,89352848,"UBE2J1",4.37,0.65,0.15,-2.74,0,"down","yes"]
["chr19",49335427,49340205,"CD37",31.44,5.05,0.16,-2.64,0,"down","yes"]
["chr3",71771656,71785206,"PROK2",23.97,3.85,0.16,-2.64,0,"down","yes"]
["chr1",6590724,6602869,"KLHL21",6.93,1.11,0.16,-2.64,0,"down","yes"]
["chr2",74554086,74557554,"DOK1",5.92,0.94,0.16,-2.66,0,"down","yes"]
["chr1",23801885,23825459,"HMGCL",3.26,0.49,0.15,-2.72,0,"down","yes"]
["chr11",126355684,126414638,"ST3GAL4",5.4,0.85,0.16,-2.67,0,"down","yes"]
["chr1",36466043,36483278,"CSF3R",14.8,2.39,0.16,-2.63,0,"down","yes"]
["chr1",154582057,154608160,"ADAR",1.52,0.24,0.16,-2.67,0,"down","yes"]
["chr16",15865720,15888615,"FOPNL",3.34,0.52,0.15,-2.69,0,"down","yes"]
["chr11",95768953,95789615,"FAM76B",1.77,0.27,0.15,-2.7,0,"down","yes"]
["chr5",157241591,157255185,"ITK",1.73,0.27,0.15,-2.7,0,"down","yes"]
["chr3",101779230,101823623,"NXPE3",1.53,0.24,0.15,-2.69,0,"down","yes"]
["chr5",39371675,39425233,"DAB2",3.42,0.55,0.16,-2.64,0,"down","yes"]
["chr22",17084959,17115694,"IL17RA",4.28,0.7,0.16,-2.62,0,"down","yes"]
["chr19",11435635,11450968,"PRKCSH",4.13,0.65,0.16,-2.66,0,"down","yes"]
["chr1",192809039,192810899,"RGS2",39.64,6.49,0.16,-2.61,0,"down","yes"]
["chr2",216415113,216483017,"SMARCAL1",1.81,0.27,0.15,-2.74,0,"down","yes"]
["chr21",33403432,33437521,"IFNGR2",8.54,1.37,0.16,-2.64,0,"down","yes"]
["chr2",64228468,64252859,"AC012368.1",10.68,1.73,0.16,-2.63,0,"down","yes"]
["chr1",154156355,154183214,"TPM3",120.84,20.04,0.17,-2.59,0,"down","yes"]
["chr8",23528805,23575463,"SLC25A37",14.97,2.48,0.17,-2.6,0,"down","yes"]
["chr11",65180021,65181834,"AP003068.2",12.36,2.01,0.16,-2.62,0,"down","yes"]
["chr1",42456561,42460414,"PPCS",6.12,0.96,0.16,-2.67,0.01,"down","yes"]
["chr3",9649433,9702393,"MTMR14",6.85,1.11,0.16,-2.62,0.01,"down","yes"]
["chr5",57173948,57264679,"GPBP1",4.25,0.7,0.16,-2.61,0.01,"down","yes"]
["chr13",36301640,36346797,"SPART",1.26,0.2,0.16,-2.68,0.01,"down","yes"]
["chr12",62260357,62406119,"USP15",20.09,3.35,0.17,-2.59,0.01,"down","yes"]
["chr19",54448887,54462037,"LENG8",4.52,0.74,0.16,-2.61,0.01,"down","yes"]
["chr3",143119331,143124014,"CHST2",4.71,0.78,0.16,-2.6,0.01,"down","yes"]
["chr7",150791287,150801360,"TMEM176B",6.37,1.02,0.16,-2.65,0.01,"down","yes"]
["chr14",77717791,77761207,"SNW1",4.34,0.7,0.16,-2.64,0.01,"down","yes"]
["chr10",58334975,58370753,"UBE2D1",10.77,1.78,0.17,-2.59,0.01,"down","yes"]
["chr15",40287897,40293622,"PLCB2",7.35,1.21,0.16,-2.6,0.01,"down","yes"]
["chr2",85616169,85649280,"USP39",2.7,0.42,0.16,-2.68,0.01,"down","yes"]
["chr21",33324904,33359862,"IFNAR1",12.25,2.05,0.17,-2.58,0.01,"down","yes"]
["chr1",159918107,159925732,"TAGLN2",668.7,112.62,0.17,-2.57,0.01,"down","yes"]
["chr17",16438901,16441987,"LRRC75A-AS1",12.61,2.07,0.16,-2.61,0.01,"down","yes"]
["chrX",135520659,135582509,"INTS6L",1.32,0.21,0.16,-2.68,0.01,"down","yes"]
["chr11",130069906,130144811,"APLP2",15.05,2.53,0.17,-2.57,0.01,"down","yes"]
["chr17",18780995,18806714,"TVP23B",1.95,0.3,0.15,-2.7,0.01,"down","yes"]
["chr19",896503,913231,"R3HDM4",243.33,41.18,0.17,-2.56,0.01,"down","yes"]
["chr1",203795699,203852430,"ZC3H11A",7.7,1.29,0.17,-2.58,0.01,"down","yes"]
["chr6",85505499,85593895,"SNX14",1.87,0.3,0.16,-2.63,0.01,"down","yes"]
["chr11",85957230,86069147,"PICALM",10.58,1.79,0.17,-2.57,0.01,"down","yes"]
["chr12",51238826,51246717,"DAZAP2",9.83,1.62,0.16,-2.6,0.01,"down","yes"]
["chr6",41275204,41286719,"TREM1",18.04,3.04,0.17,-2.57,0.01,"down","yes"]
["chr2",32063707,32157637,"SPAST",1.22,0.2,0.16,-2.64,0.01,"down","yes"]
["chr11",67395670,67398410,"RAD9A",3.32,0.53,0.16,-2.66,0.01,"down","yes"]
["chr2",24564310,24768543,"NCOA1",4.31,0.72,0.17,-2.58,0.01,"down","yes"]
["chr14",20469414,20477058,"PNP",7.46,1.24,0.17,-2.59,0.01,"down","yes"]
["chr2",101001715,101007267,"RPL31",4.52,0.74,0.16,-2.62,0.01,"down","yes"]
["chr4",26362436,26435131,"RBPJ",8.5,1.44,0.17,-2.56,0.01,"down","yes"]
["chr15",40807234,40814569,"ZFYVE19",2.97,0.47,0.16,-2.67,0.01,"down","yes"]
["chr1",36466044,36479519,"CSF3R",19.11,3.25,0.17,-2.55,0.01,"down","yes"]
["chr9",136361903,136373644,"CARD9",1.12,0.18,0.16,-2.66,0.01,"down","yes"]
["chr2",162344091,162371595,"GCA",85.37,14.59,0.17,-2.55,0.01,"down","yes"]
["chr12",14511511,14567728,"PLBD1",4.96,0.77,0.16,-2.69,0.01,"down","yes"]
["chr4",94451902,94668223,"PDLIM5",3.17,0.54,0.17,-2.57,0.01,"down","yes"]
["chr13",37009494,37059686,"SUPT20H",5.33,0.9,0.17,-2.57,0.01,"down","yes"]
["chr3",133573903,133590261,"CDV3",8.03,1.36,0.17,-2.56,0.01,"down","yes"]
["chr10",110207605,110287365,"MXI1",9.57,1.63,0.17,-2.55,0.01,"down","yes"]
["chr13",28139033,28295335,"PAN3",7.9,1.35,0.17,-2.55,0.01,"down","yes"]
["chr20",46366055,46406632,"ELMO2",3.85,0.65,0.17,-2.57,0.01,"down","yes"]
["chr2",85694291,85698854,"GNLY",15.72,2.63,0.17,-2.58,0.01,"down","yes"]
["chr2",28496071,28643788,"PLB1",1.67,0.28,0.17,-2.59,0.01,"down","yes"]
["chr17",44191805,44198379,"ATXN7L3",6.59,1.12,0.17,-2.55,0.01,"down","yes"]
["chr1",202348699,202592706,"PPP1R12B",2.21,0.38,0.17,-2.54,0.01,"down","yes"]
["chr4",87007396,87135701,"AFF1",3.87,0.65,0.17,-2.57,0.01,"down","yes"]
["chr1",243125164,243200814,"CEP170",1.34,0.22,0.17,-2.59,0.01,"down","yes"]
["chr20",19212646,19722937,"SLC24A3",1.29,0.21,0.16,-2.63,0.01,"down","yes"]
["chr8",141207173,141308153,"SLC45A4",8.71,1.51,0.17,-2.53,0.01,"down","yes"]
["chr19",48619534,48630405,"SPHK2",1.39,0.22,0.16,-2.63,0.01,"down","yes"]
["chrX",154430584,154436515,"ATP6AP1",2.3,0.38,0.17,-2.59,0.01,"down","yes"]
["chr7",100852721,100867010,"SLC12A9",7.25,1.25,0.17,-2.54,0.01,"down","yes"]
["chr16",87391800,87404779,"MAP1LC3B",21.06,3.66,0.17,-2.52,0.01,"down","yes"]
["chr11",74457082,74462367,"KCNE3",16.5,2.82,0.17,-2.55,0.01,"down","yes"]
["chr11",45933481,46121010,"PHF21A",6.81,1.17,0.17,-2.54,0.01,"down","yes"]
["chr4",87160103,87220608,"KLHL8",2.92,0.5,0.17,-2.54,0.01,"down","yes"]
["chr8",52622459,52714423,"RB1CC1",4.87,0.85,0.17,-2.53,0.01,"down","yes"]
["chr1",161541765,161550623,"FCGR3A",34.58,6.05,0.18,-2.51,0.01,"down","yes"]
["chr5",115578642,115626161,"TMED7-TICAM2",1.48,0.24,0.16,-2.62,0.01,"down","yes"]
["chr1",207752123,207793646,"CD46",12.84,2.21,0.17,-2.54,0.01,"down","yes"]
["chr19",41618971,41627074,"CEACAM4",12.6,2.17,0.17,-2.54,0.01,"down","yes"]
["chr17",50965644,51120865,"SPAG9",6.04,1.05,0.17,-2.52,0.01,"down","yes"]
["chr6",73518566,73520059,"EEF1A1",38.77,6.78,0.17,-2.52,0.01,"down","yes"]
["chr11",64226287,64234281,"DNAJC4",7.34,1.27,0.17,-2.53,0.01,"down","yes"]
["chr3",152268040,152465779,"MBNL1",1.61,0.27,0.17,-2.56,0.01,"down","yes"]
["chr20",3889389,3923855,"PANK2",2.83,0.47,0.16,-2.6,0.01,"down","yes"]
["chr6",132722789,132734765,"VNN3",8.5,1.47,0.17,-2.53,0.01,"down","yes"]
["chr17",7839962,7853680,"KDM6B",22.55,4,0.18,-2.5,0.01,"down","yes"]
["chr17",4833584,4897287,"MINK1",2.3,0.39,0.17,-2.55,0.01,"down","yes"]
["chr15",81296988,81306548,"IL16",24.55,4.34,0.18,-2.5,0.01,"down","yes"]
["chr4",82927777,83012926,"LIN54",2.13,0.36,0.17,-2.58,0.01,"down","yes"]
["chr12",54497711,54548238,"NCKAP1L",14.61,2.6,0.18,-2.49,0.01,"down","yes"]
["chr15",74899987,74907121,"FAM219B",1.42,0.23,0.16,-2.6,0.01,"down","yes"]
["chr8",23432926,23457695,"ENTPD4",5.15,0.89,0.17,-2.53,0.01,"down","yes"]
["chr17",39729156,39730787,"MIEN1",12.15,2.1,0.17,-2.53,0.01,"down","yes"]
["chr1",36478914,36482934,"CSF3R",33.02,5.81,0.18,-2.51,0.01,"down","yes"]
["chr16",66586909,66588275,"CMTM2",43.19,7.59,0.18,-2.51,0.01,"down","yes"]
["chr17",42458880,42522582,"ATP6V0A1",6.5,1.15,0.18,-2.5,0.01,"down","yes"]
["chr14",75278774,75282230,"FOS",17.82,3.17,0.18,-2.49,0.01,"down","yes"]
["chr9",33673504,33677499,"PTENP1",1.15,0.19,0.17,-2.59,0.01,"down","yes"]
["chrX",77826367,77895568,"MAGT1",2.9,0.51,0.17,-2.52,0.01,"down","yes"]
["chr19",8413303,8439011,"2-Mar",14.54,2.57,0.18,-2.5,0.01,"down","yes"]
["chr11",104944753,104968547,"CASP4",8.12,1.41,0.17,-2.52,0.01,"down","yes"]
["chr17",32142454,32225770,"RHOT1",2.57,0.45,0.17,-2.53,0.01,"down","yes"]
["chr13",52455439,52465843,"CKAP2",2.61,0.44,0.17,-2.57,0.01,"down","yes"]
["chr17",16438985,16441830,"LRRC75A-AS1",12.85,2.25,0.18,-2.51,0.01,"down","yes"]
["chr19",41310189,41324883,"CCDC97",16.02,2.88,0.18,-2.48,0.01,"down","yes"]
["chr12",29337352,29381153,"ERGIC2",5.13,0.92,0.18,-2.49,0.01,"down","yes"]
["chr5",179550558,179610026,"RUFY1",4.83,0.85,0.18,-2.5,0.01,"down","yes"]
["chr4",184755601,184826094,"ACSL1",53.46,9.7,0.18,-2.46,0.01,"down","yes"]
["chr16",28605196,28623338,"SULT1A1",8.63,1.54,0.18,-2.49,0.01,"down","yes"]
["chr22",42059802,42070842,"NAGA",2.15,0.35,0.17,-2.6,0.01,"down","yes"]
["chr19",51410022,51417581,"SIGLEC10",2.44,0.42,0.17,-2.55,0.01,"down","yes"]
["chr8",100703259,100712404,"PABPC1",6.17,1.04,0.17,-2.57,0.01,"down","yes"]
["chr11",118194165,118225021,"JAML",137.31,25,0.18,-2.46,0.01,"down","yes"]
["chr10",35008551,35090642,"CUL2",1.22,0.21,0.17,-2.55,0.01,"down","yes"]
["chr19",8302127,8308300,"CD320",3.89,0.67,0.17,-2.53,0.01,"down","yes"]
["chr3",58332880,58425151,"PXK",6.65,1.18,0.18,-2.49,0.01,"down","yes"]
["chr1",36465915,36482910,"CSF3R",139.96,25.61,0.18,-2.45,0.01,"down","yes"]
["chr16",53450053,53491520,"RBL2",11,2,0.18,-2.46,0.01,"down","yes"]
["chr11",61950370,61965515,"BEST1",3.03,0.54,0.18,-2.48,0.01,"down","yes"]
["chr17",42314852,42320687,"STAT3",13.84,2.51,0.18,-2.46,0.01,"down","yes"]
["chr16",10877216,10908887,"CIITA",1.14,0.19,0.17,-2.58,0.01,"down","yes"]
["chr7",832501,874902,"SUN1",1.01,0.17,0.17,-2.55,0.01,"down","yes"]
["chr19",45815428,45863144,"SYMPK",1.49,0.26,0.18,-2.5,0.01,"down","yes"]
["chr11",95832882,95924295,"MTMR2",1.85,0.33,0.18,-2.49,0.01,"down","yes"]
["chrX",13689125,13710506,"RAB9A",3.79,0.67,0.18,-2.49,0.01,"down","yes"]
["chr19",47309750,47322071,"C5AR1",6.74,1.23,0.18,-2.46,0.01,"down","yes"]
["chr2",159712499,159771027,"7-Mar",4.73,0.87,0.18,-2.45,0.01,"down","yes"]
["chr1",40040233,40072649,"CAP1",24.85,4.6,0.19,-2.43,0.01,"down","yes"]
["chr12",48921961,48925510,"FKBP11",1.47,0.25,0.17,-2.58,0.01,"down","yes"]
["chr5",31532266,31555058,"C5orf22",2.97,0.53,0.18,-2.48,0.01,"down","yes"]
["chr16",57999546,58020542,"USB1",3.27,0.56,0.17,-2.55,0.01,"down","yes"]
["chr19",35154730,35166761,"FXYD5",17.18,3.15,0.18,-2.45,0.01,"down","yes"]
["chr3",152268468,152465780,"MBNL1",1.62,0.29,0.18,-2.46,0.01,"down","yes"]
["chr1",25819906,25832941,"MTFR1L",3.46,0.62,0.18,-2.48,0.01,"down","yes"]
["chr18",9546791,9614558,"PPP4R1",5.43,1,0.18,-2.44,0.01,"down","yes"]
["chr8",129841697,130016543,"FAM49B",14.13,2.61,0.18,-2.44,0.01,"down","yes"]
["chr7",108562227,108569723,"THAP5",2.87,0.52,0.18,-2.46,0.01,"down","yes"]
["chr2",196987488,197310666,"ANKRD44",1.8,0.32,0.18,-2.47,0.01,"down","yes"]
["chr6",31586202,31588909,"LST1",5.19,0.94,0.18,-2.46,0.01,"down","yes"]
["chr10",133278630,133302981,"TUBGCP2",6.53,1.21,0.19,-2.43,0.01,"down","yes"]
["chr19",45782947,45792802,"DMWD",1.38,0.24,0.18,-2.51,0.01,"down","yes"]
["chr14",73886871,73932511,"ZNF410",2.86,0.52,0.18,-2.47,0.01,"down","yes"]
["chr1",15847864,15940460,"SPEN",7.7,1.45,0.19,-2.41,0.01,"down","yes"]
["chr17",32142466,32225727,"RHOT1",1.3,0.23,0.18,-2.51,0.01,"down","yes"]
["chr12",121400119,121424348,"RNF34",4.2,0.77,0.18,-2.45,0.01,"down","yes"]
["chr11",59852800,59866575,"TCN1",3.97,0.71,0.18,-2.49,0.01,"down","yes"]
["chr4",82422564,82429866,"HNRNPDL",3.5,0.65,0.18,-2.44,0.01,"down","yes"]
["chr4",82422565,82430225,"HNRNPDL",3.2,0.59,0.18,-2.44,0.01,"down","yes"]
["chr8",43140455,43202855,"HGSNAT",4.31,0.81,0.19,-2.42,0.01,"down","yes"]
["chr8",22551695,22575788,"SORBS3",1.11,0.19,0.17,-2.54,0.01,"down","yes"]
["chr10",13317424,13348297,"SEPHS1",1.63,0.29,0.18,-2.48,0.01,"down","yes"]
["chr18",9914062,9954358,"VAPA",13.13,2.45,0.19,-2.42,0.01,"down","yes"]
["chr14",105702715,105914615,"IGHA1",31.02,5.89,0.19,-2.4,0.01,"down","yes"]
["chr3",38139423,38143019,"MYD88",1.36,0.24,0.18,-2.5,0.01,"down","yes"]
["chr11",308121,309410,"IFITM2",42.4,8.01,0.19,-2.4,0.01,"down","yes"]
["chr10",103088038,103187247,"NT5C2",2.24,0.41,0.18,-2.45,0.01,"down","yes"]
["chr6",134169252,134230485,"SGK1",7.59,1.42,0.19,-2.41,0.01,"down","yes"]
["chr9",114336165,114376964,"AKNA",1.23,0.22,0.18,-2.48,0.01,"down","yes"]
["chr6",136258586,136289829,"BCLAF1",1.38,0.25,0.18,-2.45,0.01,"down","yes"]
["chr17",16438987,16442028,"LRRC75A-AS1",16.67,3.13,0.19,-2.42,0.01,"down","yes"]
["chr9",132261356,132311856,"SETX",4.06,0.77,0.19,-2.4,0.01,"down","yes"]
["chr7",75042183,75073793,"RCC1L",3.91,0.72,0.18,-2.44,0.01,"down","yes"]
["chr16",29808636,29811985,"AC009133.1",1.75,0.31,0.18,-2.48,0.01,"down","yes"]
["chr6",31582620,31588909,"LST1",5.25,0.93,0.18,-2.49,0.01,"down","yes"]
["chr17",38718583,38727192,"MLLT6",1.3,0.23,0.18,-2.48,0.01,"down","yes"]
["chr6",31586202,31588909,"LST1",6.8,1.24,0.18,-2.46,0.01,"down","yes"]
["chr17",36103590,36105621,"CCL4",23.5,4.45,0.19,-2.4,0.01,"down","yes"]
["chr16",25111729,25178231,"LCMT1",4.57,0.83,0.18,-2.46,0.01,"down","yes"]
["chr19",36141179,36149866,"CAPNS1",12.04,2.23,0.19,-2.43,0.01,"down","yes"]
["chr15",73994729,74047812,"PML",1.83,0.34,0.19,-2.42,0.01,"down","yes"]
["chr6",132743870,132757883,"VNN2",10.16,1.93,0.19,-2.4,0.01,"down","yes"]
["chr6",36442767,36491143,"KCTD20",1.03,0.19,0.18,-2.47,0.01,"down","yes"]
["chr2",37344574,37373322,"QPCT",57.95,11.19,0.19,-2.37,0.01,"down","yes"]
["chr22",29327682,29388583,"AP1B1",7.92,1.52,0.19,-2.38,0.01,"down","yes"]
["chr1",174964281,174991823,"RABGAP1L",4.6,0.87,0.19,-2.4,0.01,"down","yes"]
["chr1",26543112,26575014,"RPS6KA1",3.89,0.73,0.19,-2.41,0.01,"down","yes"]
["chr6",131586733,131628229,"MED23",2.67,0.51,0.19,-2.4,0.01,"down","yes"]
["chr9",36144276,36163902,"GLIPR2",1.71,0.3,0.18,-2.49,0.01,"down","yes"]
["chr7",100466519,100479279,"TSC22D4",9.57,1.83,0.19,-2.38,0.01,"down","yes"]
["chr18",59899948,59904306,"PMAIP1",3.96,0.74,0.19,-2.42,0.01,"down","yes"]
["chr1",26529767,26575025,"RPS6KA1",6.72,1.3,0.19,-2.37,0.01,"down","yes"]
["chr1",244839747,244843280,"COX20",1.56,0.28,0.18,-2.47,0.01,"down","yes"]
["chr1",71065719,71081289,"ZRANB2",7.9,1.51,0.19,-2.39,0.01,"down","yes"]
["chr2",37250505,37324834,"PRKD3",2.68,0.51,0.19,-2.38,0.01,"down","yes"]
["chr19",54218595,54219355,"LILRB3",10.25,1.84,0.18,-2.47,0.01,"down","yes"]
["chr12",79773107,79935952,"PPP1R12A",11.13,2.18,0.2,-2.35,0.01,"down","yes"]
["chr5",178711592,178730702,"ZNF354A",1.85,0.34,0.18,-2.44,0.01,"down","yes"]
["chr4",108048377,108165255,"LEF1",2.66,0.48,0.18,-2.46,0.01,"down","yes"]
["chrX",15500829,15556529,"BMX",2.07,0.38,0.18,-2.44,0.01,"down","yes"]
["chr8",70573442,70608369,"TRAM1",19.97,3.94,0.2,-2.34,0.01,"down","yes"]
["chr16",1938210,1943326,"MSRB1",61.59,12.18,0.2,-2.34,0.01,"down","yes"]
["chr10",63167590,63269066,"JMJD1C",20.19,4,0.2,-2.33,0.01,"down","yes"]
["chr9",2017586,2193300,"SMARCA2",7.99,1.58,0.2,-2.34,0.01,"down","yes"]
["chr5",132996985,133026604,"ZCCHC10",2.33,0.44,0.19,-2.4,0.01,"down","yes"]
["chr1",155900183,155911402,"RIT1",5.39,1.01,0.19,-2.41,0.01,"down","yes"]
["chr6",36678658,36687339,"CDKN1A",12,2.37,0.2,-2.34,0.01,"down","yes"]
["chr10",73007217,73096850,"P4HA1",1.27,0.23,0.18,-2.45,0.01,"down","yes"]
["chr11",18480311,18526956,"TSG101",14.66,2.9,0.2,-2.34,0.01,"down","yes"]
["chr22",38957522,38963183,"APOBEC3A",2.93,0.55,0.19,-2.42,0.01,"down","yes"]
["chr4",80185270,80204326,"PRDM8",1.09,0.2,0.18,-2.44,0.01,"down","yes"]
["chr6",32184741,32190186,"PBX2",13.15,2.62,0.2,-2.33,0.01,"down","yes"]
["chr12",6867119,6870948,"TPI1",8.49,1.67,0.2,-2.35,0.01,"down","yes"]
["chr19",49335396,49340575,"CD37",20.79,4.13,0.2,-2.33,0.01,"down","yes"]
["chr22",36860988,36878015,"NCF4",48.59,9.72,0.2,-2.32,0.01,"down","yes"]
["chr17",16438822,16470453,"LRRC75A-AS1",11.16,2.13,0.19,-2.39,0.01,"down","yes"]
["chr2",46617151,46625742,"CRIPT",2.4,0.45,0.19,-2.41,0.01,"down","yes"]
["chr19",16143691,16158564,"HSH2D",1.89,0.35,0.19,-2.42,0.01,"down","yes"]
["chr5",109334713,109383433,"PJA2",2.3,0.45,0.19,-2.36,0.01,"down","yes"]
["chr7",1537487,1542686,"MAFK",2,0.38,0.19,-2.4,0.01,"down","yes"]
["chr16",1938234,1943293,"MSRB1",63.17,12.69,0.2,-2.32,0.01,"down","yes"]
["chr22",31281679,31290726,"PIK3IP1",3.32,0.65,0.2,-2.36,0.01,"down","yes"]
["chr1",88684222,88836255,"PKN2",6.2,1.24,0.2,-2.32,0.01,"down","yes"]
["chrX",155216366,155239817,"VBP1",6.25,1.23,0.2,-2.35,0.01,"down","yes"]
["chr19",38836395,38852347,"HNRNPL",3.75,0.72,0.19,-2.37,0.01,"down","yes"]
["chr11",64226290,64230016,"NUDT22",4.38,0.83,0.19,-2.39,0.01,"down","yes"]
["chr21",25880550,26170654,"APP",3.34,0.66,0.2,-2.34,0.01,"down","yes"]
["chr2",105264391,105308321,"TGFBRAP1",2.23,0.44,0.2,-2.34,0.01,"down","yes"]
["chr1",156150019,156177744,"SEMA4A",3.59,0.71,0.2,-2.34,0.02,"down","yes"]
["chr1",226977404,226987544,"COQ8A",4.01,0.79,0.2,-2.34,0.02,"down","yes"]
["chr17",40342363,40356795,"RARA",14.59,2.94,0.2,-2.31,0.02,"down","yes"]
["chr9",74722495,74888094,"TRPM6",1.35,0.27,0.2,-2.34,0.02,"down","yes"]
["chr9",15422704,15464134,"SNAPC3",1.19,0.23,0.19,-2.37,0.02,"down","yes"]
["chr10",19816677,20249549,"PLXDC2",9.79,1.97,0.2,-2.32,0.02,"down","yes"]
["chrX",46836940,46882358,"RP2",12.82,2.6,0.2,-2.3,0.02,"down","yes"]
["chr2",30146961,30160533,"YPEL5",28.05,5.72,0.2,-2.3,0.02,"down","yes"]
["chr6",136256627,136289847,"BCLAF1",1.11,0.22,0.2,-2.34,0.02,"down","yes"]
["chr15",40844018,40857655,"SPINT1",1.85,0.35,0.19,-2.38,0.02,"down","yes"]
["chr1",179025896,179076562,"FAM20B",2.67,0.54,0.2,-2.31,0.02,"down","yes"]
["chr12",76046904,76083947,"NAP1L1",10.04,2.04,0.2,-2.3,0.02,"down","yes"]
["chr2",232697352,232819982,"GIGYF2",1.76,0.34,0.19,-2.38,0.02,"down","yes"]
["chr6",41267926,41286665,"TREM1",7.19,1.4,0.19,-2.36,0.02,"down","yes"]
["chr5",176526697,176537420,"RNF44",6.41,1.31,0.2,-2.29,0.02,"down","yes"]
["chr14",21211418,21269442,"HNRNPC",34.16,6.98,0.2,-2.29,0.02,"down","yes"]
["chr9",113221562,113264492,"SLC31A1",3.73,0.76,0.2,-2.3,0.02,"down","yes"]
["chr10",70147289,70170523,"SAR1A",3.99,0.81,0.2,-2.3,0.02,"down","yes"]
["chr5",65926574,66081023,"ERBIN",2.47,0.5,0.2,-2.3,0.02,"down","yes"]
["chr16",31060850,31074320,"ZNF668",1.23,0.23,0.19,-2.4,0.02,"down","yes"]
["chr15",63907036,64040267,"DAPK2",1.2,0.24,0.2,-2.35,0.02,"down","yes"]
["chr17",41866908,41918987,"ACLY",10.64,2.19,0.21,-2.28,0.02,"down","yes"]
["chr1",3489920,3531448,"MEGF6",1.09,0.21,0.2,-2.35,0.02,"down","yes"]
["chr13",45393316,45418380,"SLC25A30",2.61,0.52,0.2,-2.32,0.02,"down","yes"]
["chr14",94382804,94390676,"SERPINA1",8.98,1.8,0.2,-2.32,0.02,"down","yes"]
["chr1",89006666,89022882,"GBP3",2.78,0.56,0.2,-2.31,0.02,"down","yes"]
["chr6",30676389,30684744,"PPP1R18",139.95,29.05,0.21,-2.27,0.02,"down","yes"]
["chr15",58138196,58185911,"AQP9",147.32,30.61,0.21,-2.27,0.02,"down","yes"]
["chr16",31090842,31094957,"VKORC1",14.4,2.94,0.2,-2.29,0.02,"down","yes"]
["chr11",104942870,104950992,"CASP4",1.69,0.34,0.2,-2.32,0.02,"down","yes"]
["chr2",86503431,86563477,"CHMP3",7.99,1.64,0.21,-2.28,0.02,"down","yes"]
["chr2",99169263,99180962,"MITD1",1.09,0.21,0.19,-2.4,0.02,"down","yes"]
["chr14",89159358,89619140,"FOXN3",4.87,1,0.21,-2.28,0.02,"down","yes"]
["chr6",111660332,111873452,"FYN",1.34,0.26,0.2,-2.34,0.02,"down","yes"]
["chr19",49335400,49340466,"CD37",39.68,8.22,0.21,-2.27,0.02,"down","yes"]
["chr8",73792360,73878825,"UBE2W",3.99,0.8,0.2,-2.32,0.02,"down","yes"]
["chr16",89093809,89155846,"ACSF3",1.26,0.25,0.2,-2.33,0.02,"down","yes"]
["chr22",37226753,37244441,"RAC2",5,0.97,0.19,-2.37,0.02,"down","yes"]
["chr10",23095506,23122013,"MSRB2",4.57,0.92,0.2,-2.31,0.02,"down","yes"]
["chr14",50719763,50831121,"NIN",2.92,0.6,0.21,-2.27,0.02,"down","yes"]
["chr14",23058567,23069525,"ACIN1",5.49,1.13,0.21,-2.28,0.02,"down","yes"]
["chr7",74210006,74229831,"LAT2",38.83,8.12,0.21,-2.26,0.02,"down","yes"]
["chr21",25585656,25607517,"MRPL39",3.43,0.66,0.19,-2.37,0.02,"down","yes"]
["chr9",111661335,111670246,"GNG10",19.76,4.11,0.21,-2.27,0.02,"down","yes"]
["chr13",21373571,21459330,"ZDHHC20",6.55,1.36,0.21,-2.26,0.02,"down","yes"]
["chr19",41431319,41439905,"DMAC2",3.85,0.77,0.2,-2.32,0.02,"down","yes"]
["chr1",206685037,206734283,"MAPKAPK2",28.18,5.93,0.21,-2.25,0.02,"down","yes"]
["chr19",4360370,4400547,"SH3GL1",13.9,2.91,0.21,-2.25,0.02,"down","yes"]
["chr4",78551519,78610421,"ANXA3",23.44,4.92,0.21,-2.25,0.02,"down","yes"]
["chr3",71682727,71753624,"EIF4E3",8.77,1.83,0.21,-2.26,0.02,"down","yes"]
["chr17",40922696,40937420,"KRT23",12.93,2.71,0.21,-2.26,0.02,"down","yes"]
["chr7",150800403,150805109,"TMEM176A",6.16,1.26,0.21,-2.28,0.02,"down","yes"]
["chr9",127731524,127735317,"TOR2A",2.91,0.58,0.2,-2.33,0.02,"down","yes"]
["chr12",57097068,57111413,"STAT6",1.18,0.23,0.2,-2.35,0.02,"down","yes"]
["chr1",161581340,161599803,"FCGR2C",2.99,0.59,0.2,-2.35,0.02,"down","yes"]
["chr8",125091853,125367120,"NSMCE2",5.16,1.05,0.2,-2.3,0.02,"down","yes"]
["chr17",40309192,40348336,"RARA",9.32,1.89,0.2,-2.3,0.02,"down","yes"]
["chr1",220879400,220885059,"HLX",13.22,2.78,0.21,-2.25,0.02,"down","yes"]
["chr1",44775578,44777525,"RPS8",4.11,0.82,0.2,-2.33,0.02,"down","yes"]
["chr2",219251194,219253916,"TUBA4A",7.23,1.47,0.2,-2.3,0.02,"down","yes"]
["chr1",192809042,192811239,"RGS2",21.13,4.42,0.21,-2.26,0.02,"down","yes"]
["chr9",35658314,35661511,"CCDC107",2.79,0.54,0.19,-2.37,0.02,"down","yes"]
["chr10",11165080,11334106,"CELF2",5.41,1.15,0.21,-2.24,0.02,"down","yes"]
["chr10",74176686,74709303,"ADK",2.19,0.44,0.2,-2.31,0.02,"down","yes"]
["chr19",51410021,51417636,"SIGLEC10",2.38,0.48,0.2,-2.3,0.02,"down","yes"]
["chr5",131264075,131394690,"CDC42SE2",12.94,2.75,0.21,-2.24,0.02,"down","yes"]
["chrX",130064928,130110495,"ELF4",7.03,1.49,0.21,-2.24,0.02,"down","yes"]
["chr2",37344594,37372742,"QPCT",9.03,1.87,0.21,-2.27,0.02,"down","yes"]
["chr1",27322145,27336399,"TMEM222",3.35,0.68,0.2,-2.31,0.02,"down","yes"]
["chr10",29457364,29736078,"SVIL",4.68,0.99,0.21,-2.24,0.02,"down","yes"]
["chr19",18110022,18151692,"MAST3",2.32,0.49,0.21,-2.25,0.02,"down","yes"]
["chr19",45507416,45526983,"VASP",24.82,5.29,0.21,-2.23,0.02,"down","yes"]
["chr19",36115813,36125709,"TBCB",8.72,1.79,0.21,-2.28,0.02,"down","yes"]
["chr21",44885956,44920875,"ITGB2",41.27,8.83,0.21,-2.22,0.02,"down","yes"]
["chr1",229271194,229303894,"RAB4A",5.4,1.07,0.2,-2.33,0.02,"down","yes"]
["chr19",18559112,18569378,"KXD1",2.3,0.47,0.2,-2.29,0.02,"down","yes"]
["chr20",64073181,64077530,"RGS19",6.77,1.42,0.21,-2.25,0.02,"down","yes"]
["chr7",44565417,44574002,"DDX56",5.33,1.12,0.21,-2.25,0.02,"down","yes"]
["chr4",499289,522843,"PIGG",1.42,0.29,0.2,-2.31,0.02,"down","yes"]
["chr1",15684332,15734769,"PLEKHM2",6.28,1.33,0.21,-2.23,0.02,"down","yes"]
["chr19",45071500,45076588,"ZNF296",1.81,0.35,0.2,-2.35,0.02,"down","yes"]
["chr7",141927357,141946983,"CLEC5A",1.89,0.39,0.21,-2.27,0.02,"down","yes"]
["chr12",122701271,122716892,"HCAR3",20.43,4.38,0.21,-2.22,0.02,"down","yes"]
["chr4",152618632,152680165,"TMEM154",8.08,1.74,0.22,-2.22,0.02,"down","yes"]
["chr20",18508062,18561415,"SEC23B",2.79,0.59,0.21,-2.25,0.02,"down","yes"]
["chr17",1569267,1628836,"SLC43A2",8.5,1.83,0.22,-2.21,0.02,"down","yes"]
["chr7",90596497,91210590,"CDK14",3.16,0.67,0.21,-2.23,0.02,"down","yes"]
["chr19",54094670,54100815,"OSCAR",2.71,0.55,0.21,-2.29,0.02,"down","yes"]
["chr12",49184796,49189324,"TUBA1A",49.52,10.69,0.22,-2.21,0.02,"down","yes"]
["chr16",89560681,89563080,"RPL13",66.56,14.32,0.22,-2.22,0.02,"down","yes"]
["chr3",187722320,187743672,"BCL6",7.2,1.55,0.22,-2.21,0.02,"down","yes"]
["chr17",42315491,42388482,"STAT3",12.57,2.7,0.21,-2.22,0.02,"down","yes"]
["chr17",44308413,44318670,"RUNDC3A",2.08,0.43,0.2,-2.29,0.02,"down","yes"]
["chr11",73872669,73876674,"COA4",4.57,0.92,0.2,-2.31,0.02,"down","yes"]
["chr6",132749749,132757904,"VNN2",3.4,0.7,0.2,-2.29,0.02,"down","yes"]
["chr1",203178931,203186749,"CHI3L1",20.57,4.44,0.22,-2.21,0.02,"down","yes"]
["chrX",16946862,17153272,"REPS2",3.88,0.84,0.22,-2.21,0.02,"down","yes"]
["chr7",149547154,149624727,"ZNF767P",2.81,0.6,0.21,-2.23,0.02,"down","yes"]
["chr12",8940365,8949955,"M6PR",25.4,5.53,0.22,-2.2,0.02,"down","yes"]
["chr11",10304680,10307397,"ADM",14.34,3.11,0.22,-2.21,0.02,"down","yes"]
["chr19",38305114,38315923,"YIF1B",3.02,0.62,0.21,-2.28,0.02,"down","yes"]
["chrX",74585217,74614617,"RLIM",4.06,0.88,0.22,-2.2,0.02,"down","yes"]
["chr13",110523066,110561733,"RAB20",4.57,0.96,0.21,-2.25,0.02,"down","yes"]
["chr13",48488959,48533233,"RCBTB2",6.58,1.42,0.22,-2.21,0.02,"down","yes"]
["chr20",1894167,1939894,"SIRPA",17,3.72,0.22,-2.19,0.02,"down","yes"]
["chr19",53793603,53824343,"NLRP12",14.63,3.2,0.22,-2.19,0.02,"down","yes"]
["chr22",36467036,36482030,"TXN2",14.85,3.23,0.22,-2.2,0.02,"down","yes"]
["chr11",64764606,64778730,"SF1",5.28,1.14,0.22,-2.21,0.02,"down","yes"]
["chr12",51281038,51324198,"BIN2",136.18,29.94,0.22,-2.19,0.02,"down","yes"]
["chr14",24115326,24123796,"DCAF11",4.93,1.06,0.22,-2.21,0.02,"down","yes"]
["chr2",71453722,71686648,"DYSF",7.05,1.54,0.22,-2.19,0.02,"down","yes"]
["chr8",37736627,37759101,"ERLIN2",1.78,0.38,0.22,-2.22,0.02,"down","yes"]
["chr2",200889327,200897198,"NIF3L1",8,1.7,0.21,-2.24,0.02,"down","yes"]
["chr18",50268847,50281774,"MBD1",1.49,0.31,0.21,-2.27,0.02,"down","yes"]
["chr16",66552567,66566072,"CKLF",20.44,4.42,0.22,-2.21,0.02,"down","yes"]
["chr19",55385934,55388888,"RPL28",29.74,6.51,0.22,-2.19,0.02,"down","yes"]
["chr5",131264040,131394556,"CDC42SE2",13.2,2.9,0.22,-2.19,0.02,"down","yes"]
["chr12",124911727,124913717,"UBC",4.18,0.85,0.2,-2.29,0.02,"down","yes"]
["chr17",81228928,81239033,"TEPSIN",2.8,0.59,0.21,-2.25,0.02,"down","yes"]
["chr6",31270221,31272130,"HLA-C",237.86,52.73,0.22,-2.17,0.02,"down","yes"]
["chr11",62676502,62679095,"UBXN1",13.01,2.85,0.22,-2.19,0.02,"down","yes"]
["chr6",31639028,31652639,"BAG6",8.47,1.87,0.22,-2.18,0.02,"down","yes"]
["chr2",69915071,69942945,"MXD1",56.58,12.55,0.22,-2.17,0.02,"down","yes"]
["chr11",64359148,64372215,"RPS6KA4",1.17,0.24,0.21,-2.28,0.02,"down","yes"]
["chrX",12906639,12922202,"TLR8",3.51,0.76,0.22,-2.2,0.02,"down","yes"]
["chr6",33420070,33457541,"SYNGAP1",1.54,0.33,0.22,-2.2,0.02,"down","yes"]
["chr1",36339624,36385884,"STK40",2.36,0.51,0.22,-2.21,0.02,"down","yes"]
["chr6",53268076,53335347,"ELOVL5",50.79,11.28,0.22,-2.17,0.02,"down","yes"]
["chr4",10075149,10093019,"WDR1",1.4,0.3,0.21,-2.24,0.02,"down","yes"]
["chr14",74480187,74493347,"NPC2",4.15,0.87,0.21,-2.25,0.02,"down","yes"]
["chr1",247418049,247448817,"NLRP3",2.15,0.46,0.22,-2.21,0.02,"down","yes"]
["chr7",92112151,92134530,"CYP51A1",1.31,0.27,0.21,-2.26,0.02,"down","yes"]
["chr6",33065007,33073615,"HLA-DPA1",5.42,1.2,0.22,-2.18,0.02,"down","yes"]
["chr17",3860315,3893044,"CAMKK1",2.68,0.58,0.22,-2.21,0.02,"down","yes"]
["chr5",160075882,160119423,"PWWP2A",2.35,0.51,0.22,-2.2,0.02,"down","yes"]
["chr10",96043394,96060870,"CCNJ",1.24,0.26,0.21,-2.24,0.02,"down","yes"]
["chr18",23503519,23531776,"C18orf8",2.78,0.59,0.21,-2.23,0.02,"down","yes"]
["chr5",141640355,141651420,"FCHSD1",6.69,1.48,0.22,-2.18,0.02,"down","yes"]
["chr11",112084800,112086798,"TIMM8B",3.91,0.83,0.21,-2.23,0.02,"down","yes"]
["chr4",6909444,7033118,"TBC1D14",1.76,0.38,0.22,-2.2,0.02,"down","yes"]
["chr7",44748931,44769881,"ZMIZ2",2.12,0.46,0.22,-2.2,0.02,"down","yes"]
["chr19",44809103,44821414,"BCAM",1.45,0.3,0.21,-2.28,0.02,"down","yes"]
["chr10",110226035,110284890,"MXI1",7.17,1.54,0.21,-2.22,0.03,"down","yes"]
["chr5",10353703,10433961,"6-Mar",3.73,0.82,0.22,-2.18,0.03,"down","yes"]
["chr1",207104262,207144972,"C4BPA",5.39,1.19,0.22,-2.18,0.03,"down","yes"]
["chr6",31268964,31357196,"HLA-C",39.61,8.9,0.22,-2.15,0.03,"down","yes"]
["chr17",59707651,59765068,"VMP1",14.03,3.06,0.22,-2.2,0.03,"down","yes"]
["chr6",73519341,73523797,"EEF1A1",23.44,5.19,0.22,-2.18,0.03,"down","yes"]
["chr15",99565928,99716422,"MEF2A",2.96,0.66,0.22,-2.17,0.03,"down","yes"]
["chr17",19770830,19867936,"ULK2",1.14,0.24,0.21,-2.22,0.03,"down","yes"]
["chr4",169660062,169723187,"CLCN3",1.11,0.24,0.22,-2.2,0.03,"down","yes"]
["chr12",56116599,56117844,"RPL41",29.92,6.68,0.22,-2.16,0.03,"down","yes"]
["chr10",69088118,69104811,"SRGN",53.43,12.05,0.23,-2.15,0.03,"down","yes"]
["chr16",48244333,48351899,"LONP2",1.77,0.38,0.21,-2.24,0.03,"down","yes"]
["chrX",153929926,153935015,"NAA10",3.26,0.69,0.21,-2.25,0.03,"down","yes"]
["chr6",36968141,36986298,"MTCH1",14.45,3.25,0.22,-2.15,0.03,"down","yes"]
["chr7",141995879,142106747,"MGAM",20.37,4.61,0.23,-2.14,0.03,"down","yes"]
["chr9",133031004,133058501,"GTF3C5",2.32,0.49,0.21,-2.23,0.03,"down","yes"]
["chr3",155079660,155183960,"MME",6.78,1.53,0.23,-2.15,0.03,"down","yes"]
["chr12",109950694,109996373,"GIT2",1.8,0.38,0.21,-2.24,0.03,"down","yes"]
["chr14",103126327,103137439,"TNFAIP2",3.36,0.75,0.22,-2.17,0.03,"down","yes"]
["chr12",96280424,96400480,"CDK17",5.93,1.32,0.22,-2.16,0.03,"down","yes"]
["chr17",82229032,82239479,"SLC16A3",15.65,3.53,0.23,-2.15,0.03,"down","yes"]
["chr8",89901859,89927868,"OSGIN2",3.21,0.72,0.22,-2.17,0.03,"down","yes"]
["chr22",17084959,17115693,"IL17RA",36.55,8.32,0.23,-2.14,0.03,"down","yes"]
["chr16",67873052,67884495,"EDC4",2.67,0.6,0.22,-2.16,0.03,"down","yes"]
["chr7",100200653,100272206,"GATS",1.57,0.34,0.22,-2.21,0.03,"down","yes"]
["chr8",133049332,133075027,"SLA",3.32,0.7,0.21,-2.25,0.03,"down","yes"]
["chr6",28903002,28923913,"TRIM27",2.9,0.65,0.23,-2.15,0.03,"down","yes"]
["chr12",89351015,89353271,"AC024909.3",2.44,0.53,0.22,-2.21,0.03,"down","yes"]
["chr15",70049799,70097888,"TLE3",10.44,2.38,0.23,-2.14,0.03,"down","yes"]
["chr6",36968141,36986298,"MTCH1",24.31,5.54,0.23,-2.13,0.03,"down","yes"]
["chr7",27740189,27829263,"TAX1BP1",1.9,0.42,0.22,-2.19,0.03,"down","yes"]
["chr6",108986442,109009555,"SESN1",1.98,0.43,0.22,-2.2,0.03,"down","yes"]
["chr10",100505628,100529871,"AL133352.1",1.78,0.38,0.21,-2.22,0.03,"down","yes"]
["chr11",34113803,34146903,"NAT10",1.29,0.28,0.22,-2.2,0.03,"down","yes"]
["chr1",198639019,198759289,"PTPRC",40.09,9.2,0.23,-2.12,0.03,"down","yes"]
["chr10",71747559,71773498,"VSIR",141.37,32.45,0.23,-2.12,0.03,"down","yes"]
["chr19",49869046,49878028,"AKT1S1",5.33,1.2,0.23,-2.15,0.03,"down","yes"]
["chr4",10075149,10116727,"WDR1",4.56,1.02,0.22,-2.16,0.03,"down","yes"]
["chr5",109862328,109869625,"MAN2A1",1.01,0.22,0.22,-2.19,0.03,"down","yes"]
["chr1",36468748,36475412,"CSF3R",3.43,0.75,0.22,-2.19,0.03,"down","yes"]
["chr1",178725165,178920103,"RALGPS2",1.36,0.3,0.22,-2.17,0.03,"down","yes"]
["chr8",141184488,141195807,"DENND3",3.6,0.82,0.23,-2.14,0.03,"down","yes"]
["chr10",103088038,103187247,"NT5C2",3.07,0.69,0.23,-2.15,0.03,"down","yes"]
["chr11",118253403,118264282,"MPZL2",2.81,0.62,0.22,-2.17,0.03,"down","yes"]
["chr6",31586124,31588909,"LST1",17.72,4.01,0.23,-2.14,0.03,"down","yes"]
["chr2",46941174,47076135,"TTC7A",10.66,2.45,0.23,-2.12,0.03,"down","yes"]
["chr4",155980971,156010374,"FTH1P21",7.54,1.65,0.22,-2.19,0.03,"down","yes"]
["chr17",48136938,48430219,"SKAP1",4.01,0.89,0.22,-2.18,0.03,"down","yes"]
["chr1",27612300,27635200,"FGR",6.31,1.43,0.23,-2.14,0.03,"down","yes"]
["chr12",55757274,55817756,"SARNP",6.15,1.36,0.22,-2.18,0.03,"down","yes"]
["chr18",6462144,6463010,"AP005202.1",40.96,9.45,0.23,-2.12,0.03,"down","yes"]
["chr12",57472266,57477851,"ARHGAP9",12.04,2.77,0.23,-2.12,0.03,"down","yes"]
["chr20",64073181,64077571,"RGS19",5.86,1.33,0.23,-2.14,0.03,"down","yes"]
["chr7",100373528,100400096,"PILRA",11.71,2.66,0.23,-2.14,0.03,"down","yes"]
["chr10",110290730,110304951,"SMNDC1",4.94,1.14,0.23,-2.12,0.03,"down","yes"]
["chr10",72692143,72871545,"MCU",4.64,1.03,0.22,-2.17,0.03,"down","yes"]
["chr16",30183619,30189034,"CORO1A",276.72,64.55,0.23,-2.1,0.03,"down","yes"]
["chr3",71754050,71756496,"GPR27",8.44,1.94,0.23,-2.12,0.03,"down","yes"]
["chrX",118495882,118687015,"DOCK11",6.18,1.44,0.23,-2.1,0.03,"down","yes"]
["chr16",67987394,67999453,"DPEP2",15.14,3.51,0.23,-2.11,0.03,"down","yes"]
["chr10",73792731,73801792,"ZSWIM8",1.46,0.33,0.22,-2.16,0.03,"down","yes"]
["chr3",119826686,120093666,"GSK3B",3.57,0.8,0.22,-2.16,0.03,"down","yes"]
["chr5",138156882,138178630,"BRD8",3.39,0.78,0.23,-2.13,0.03,"down","yes"]
["chr7",150625378,150632648,"GIMAP6",1.52,0.34,0.22,-2.15,0.03,"down","yes"]
["chr9",111408571,111483679,"KIAA0368",1.05,0.22,0.21,-2.22,0.03,"down","yes"]
["chr1",153947678,153958564,"CRTC2",3.38,0.77,0.23,-2.13,0.03,"down","yes"]
["chr15",50241947,50253305,"HDC",2.48,0.55,0.22,-2.17,0.03,"down","yes"]
["chr6",31268945,31357217,"HLA-C",52.56,12.29,0.23,-2.1,0.03,"down","yes"]
["chrX",10015562,10144478,"WWC3",9.53,2.23,0.23,-2.09,0.03,"down","yes"]
["chr7",99374658,99394813,"AC004922.1",17.19,4,0.23,-2.1,0.03,"down","yes"]
["chr3",134486057,134561766,"CEP63",5.21,1.19,0.23,-2.13,0.03,"down","yes"]
["chr1",36466044,36476327,"CSF3R",8.32,1.95,0.23,-2.09,0.03,"down","yes"]
["chr17",4894544,4898060,"MINK1",2.04,0.46,0.23,-2.15,0.03,"down","yes"]
["chr8",120535745,120813273,"SNTB1",2.86,0.66,0.23,-2.11,0.03,"down","yes"]
["chr6",31952228,31958962,"NELFE",4.35,0.99,0.23,-2.14,0.03,"down","yes"]
["chr22",24427562,24441142,"SPECC1L-ADORA2A",13.41,3.13,0.23,-2.1,0.03,"down","yes"]
["chr22",50625018,50628172,"ARSA",4.17,0.95,0.23,-2.13,0.03,"down","yes"]
["chr21",33229907,33265680,"IFNAR2",5.77,1.35,0.23,-2.1,0.03,"down","yes"]
["chr1",153390032,153391188,"S100A8",432.78,102.15,0.24,-2.08,0.03,"down","yes"]
["chr14",20473384,20477087,"PNP",3.71,0.85,0.23,-2.12,0.03,"down","yes"]
["chr19",51745172,51751909,"FPR1",144.45,34.14,0.24,-2.08,0.03,"down","yes"]
["chr1",23743155,23762059,"ELOA",1.26,0.29,0.23,-2.13,0.03,"down","yes"]
["chr7",150567277,150573955,"GIMAP4",83.57,19.79,0.24,-2.08,0.03,"down","yes"]
["chr19",35154773,35169880,"FXYD5",21.46,5.05,0.24,-2.09,0.03,"down","yes"]
["chr1",27615514,27626135,"FGR",13.8,3.23,0.23,-2.09,0.03,"down","yes"]
["chr7",74289475,74405930,"CLIP2",3.32,0.78,0.23,-2.1,0.03,"down","yes"]
["chr17",7306999,7312463,"EIF5A",29.03,6.86,0.24,-2.08,0.03,"down","yes"]
["chr11",63536816,63545387,"RARRES3",5.59,1.27,0.23,-2.14,0.03,"down","yes"]
["chr2",101991844,102028544,"IL1R2",28.84,6.85,0.24,-2.07,0.03,"down","yes"]
["chr1",6580048,6589280,"ZBTB48",3.06,0.7,0.23,-2.12,0.03,"down","yes"]
["chr7",852247,874902,"SUN1",1.01,0.23,0.23,-2.14,0.03,"down","yes"]
["chr17",31303494,31321884,"AC134669.2",204.47,48.88,0.24,-2.06,0.03,"down","yes"]
["chr8",143579728,143597413,"EEF1D",5.73,1.32,0.23,-2.12,0.03,"down","yes"]
["chr15",34140674,34210079,"KATNBL1",3.39,0.79,0.23,-2.1,0.03,"down","yes"]
["chrX",40051246,40097403,"BCOR",2.7,0.64,0.24,-2.09,0.03,"down","yes"]
["chr3",71772101,71785061,"PROK2",10.23,2.39,0.23,-2.1,0.03,"down","yes"]
["chr3",5187673,5219957,"EDEM1",8.46,2.02,0.24,-2.07,0.03,"down","yes"]
["chr16",29806106,29811160,"MAZ",8.08,1.92,0.24,-2.08,0.03,"down","yes"]
["chr14",24314700,24316946,"LTB4R",7.93,1.87,0.24,-2.08,0.03,"down","yes"]
["chr8",100916525,100953397,"YWHAZ",6.01,1.44,0.24,-2.07,0.04,"down","yes"]
["chr22",29073078,29146820,"KREMEN1",4.82,1.15,0.24,-2.06,0.04,"down","yes"]
["chr11",118197609,118225011,"JAML",12.97,3.08,0.24,-2.07,0.04,"down","yes"]
["chr11",65572462,65574190,"FAM89B",12.94,3.08,0.24,-2.07,0.04,"down","yes"]
["chr3",183635568,183679478,"KLHL24",3.56,0.83,0.23,-2.09,0.04,"down","yes"]
["chr10",95755957,95866602,"ENTPD1",19.19,4.61,0.24,-2.06,0.04,"down","yes"]
["chr11",46396414,46593948,"AMBRA1",2.48,0.59,0.24,-2.08,0.04,"down","yes"]
["chr19",37334666,37364451,"HKR1",1.61,0.37,0.23,-2.13,0.04,"down","yes"]
["chr14",21210933,21269400,"HNRNPC",6.18,1.46,0.24,-2.09,0.04,"down","yes"]
["chr2",27212311,27217156,"ATRAID",2.87,0.64,0.22,-2.17,0.04,"down","yes"]
["chr8",41490562,41510974,"GOLGA7",6.48,1.54,0.24,-2.07,0.04,"down","yes"]
["chr12",51048318,51060421,"LETMD1",1.65,0.38,0.23,-2.13,0.04,"down","yes"]
["chr7",50304782,50405101,"IKZF1",18.1,4.39,0.24,-2.04,0.04,"down","yes"]
["chr15",22838687,22867716,"NIPA2",2.36,0.55,0.23,-2.1,0.04,"down","yes"]
["chr16",85613216,85676204,"GSE1",1.06,0.25,0.24,-2.09,0.04,"down","yes"]
["chr3",114291102,114310288,"TIGIT",1.98,0.46,0.23,-2.09,0.04,"down","yes"]
["chr2",179945621,180007113,"CWC22",6.54,1.57,0.24,-2.06,0.04,"down","yes"]
["chrX",119588337,119605895,"NKRF",1.83,0.43,0.23,-2.09,0.04,"down","yes"]
["chr15",64963204,64989911,"SPG21",8.29,1.98,0.24,-2.07,0.04,"down","yes"]
["chr9",34179045,34251698,"UBAP1",4.5,1.07,0.24,-2.07,0.04,"down","yes"]
["chr7",22934211,23014129,"FAM126A",1,0.24,0.24,-2.06,0.04,"down","yes"]
["chr1",11736147,11750771,"AGTRAP",6.42,1.52,0.24,-2.08,0.04,"down","yes"]
["chr1",192809143,192811032,"RGS2",8.92,2,0.22,-2.15,0.04,"down","yes"]
["chr10",36521721,36524234,"NAMPTP1",75.49,18.44,0.24,-2.03,0.04,"down","yes"]
["chr19",42507306,42528509,"CEACAM1",3.41,0.82,0.24,-2.06,0.04,"down","yes"]
["chr3",187721377,187745727,"BCL6",7.23,1.75,0.24,-2.05,0.04,"down","yes"]
["chr8",41934774,41958363,"KAT6A",1.13,0.26,0.23,-2.14,0.04,"down","yes"]
["chr2",232550052,232569210,"EIF4E2",4.52,1.08,0.24,-2.07,0.04,"down","yes"]
["chr9",137447573,137459334,"NSMF",4.02,0.97,0.24,-2.05,0.04,"down","yes"]
["chr17",50719603,50752709,"LUC7L3",10.89,2.65,0.24,-2.04,0.04,"down","yes"]
["chr12",57819927,57846739,"CTDSP2",54.18,13.36,0.25,-2.02,0.04,"down","yes"]
["chr8",38787204,38853028,"TACC1",6.08,1.49,0.25,-2.03,0.04,"down","yes"]
["chr16",53434989,53491649,"RBL2",1.56,0.37,0.24,-2.06,0.04,"down","yes"]
["chr12",6951373,6954915,"PTPN6",4.98,1.13,0.23,-2.14,0.04,"down","yes"]
["chr3",58332898,58426023,"PXK",2.35,0.56,0.24,-2.07,0.04,"down","yes"]
["chr9",121038,179058,"CBWD1",1.72,0.39,0.23,-2.15,0.04,"down","yes"]
["chr3",52245821,52250597,"PPM1M",9.13,2.23,0.24,-2.03,0.04,"down","yes"]
["chr4",40424338,40629864,"RBM47",11.56,2.85,0.25,-2.02,0.04,"down","yes"]
["chr7",103297422,103313235,"PMPCB",4.26,1.03,0.24,-2.05,0.04,"down","yes"]
["chr18",63396342,63422483,"VPS4B",1.5,0.34,0.23,-2.13,0.04,"down","yes"]
["chr17",80260866,80395312,"RNF213",6.74,1.67,0.25,-2.01,0.04,"down","yes"]
["chr19",10270835,10286615,"ICAM1",7.31,1.8,0.25,-2.02,0.04,"down","yes"]
["chr1",156742110,156751598,"HDGF",3.43,0.82,0.24,-2.06,0.04,"down","yes"]
["chr16",31108294,31112791,"BCKDK",8.19,2.02,0.25,-2.02,0.04,"down","yes"]
["chr6",30727866,30742706,"FLOT1",59.77,14.88,0.25,-2.01,0.04,"down","yes"]
["chr9",37779714,37785057,"EXOSC3",2.74,0.65,0.24,-2.08,0.04,"down","yes"]
["chr6",111661282,111759131,"FYN",4.65,1.14,0.24,-2.03,0.04,"down","yes"]
["chr2",70447280,70554015,"TGFA",3.14,0.77,0.25,-2.03,0.04,"down","yes"]
["chr15",72751369,72783785,"ADPGK",4.55,1.11,0.25,-2.03,0.04,"down","yes"]
["chr1",192809041,192812283,"RGS2",483.56,121,0.25,-2,0.04,"down","yes"]
["chr10",46005091,46030714,"NCOA4",85.69,21.45,0.25,-2,0.04,"down","yes"]
["chr5",179614181,179623168,"HNRNPH1",10.04,2.49,0.25,-2.01,0.04,"down","yes"]
["chr3",187743686,187746028,"AC072022.1",3.48,0.82,0.24,-2.08,0.04,"down","yes"]
["chr7",75533012,75639186,"HIP1",6.74,1.69,0.25,-2,0.04,"down","yes"]
["chr20",31721507,31723409,"ABALON",6.62,1.63,0.25,-2.02,0.04,"down","yes"]
["chr17",75273030,75289411,"SLC25A19",1.95,0.45,0.23,-2.11,0.04,"down","yes"]
["chr15",44711487,44718159,"B2M",128.04,32.08,0.25,-2,0.04,"down","yes"]
["chr7",73220639,73235945,"NCF1B",16.31,4.06,0.25,-2.01,0.04,"down","yes"]
["chr17",78168611,78172719,"SYNGR2",2.77,0.66,0.24,-2.07,0.04,"down","yes"]
["chr11",13719903,13732346,"FAR1",3.96,0.98,0.25,-2.01,0.04,"down","yes"]
["chr12",98645141,98733527,"APAF1",4.32,1.08,0.25,-2,0.04,"down","yes"]
["chr12",9852984,9870136,"CLEC2B",15.68,3.92,0.25,-2,0.04,"down","yes"]
["chr4",10068206,10116941,"WDR1",16.73,4.21,0.25,-1.99,0.04,"down","yes"]
["chr2",160274520,160407889,"RBMS1",15.3,3.83,0.25,-2,0.04,"down","yes"]
["chr22",21919418,21976183,"TOP3B",14.57,3.68,0.25,-1.99,0.04,"down","yes"]
["chr16",28985340,28990773,"LAT",4.38,1.07,0.24,-2.03,0.04,"down","yes"]
["chr15",70050097,70096798,"TLE3",14.38,3.61,0.25,-1.99,0.04,"down","yes"]
["chr6",24839359,24877355,"RIPOR2",11.84,2.97,0.25,-2,0.04,"down","yes"]
["chr12",56237807,56258391,"ANKRD52",4.18,1.05,0.25,-1.99,0.04,"down","yes"]
["chr17",59893164,59950564,"RPS6KB1",3.12,0.78,0.25,-2,0.04,"down","yes"]
["chr15",78872973,78893018,"MORF4L1",2.25,0.52,0.23,-2.11,0.04,"down","yes"]
["chr1",186671791,186680427,"PTGS2",5.7,1.43,0.25,-1.99,0.05,"down","yes"]
["chrX",150766337,150898706,"CD99L2",5.99,1.5,0.25,-1.99,0.05,"down","yes"]
["chr22",37746233,37774140,"TRIOBP",11.96,3.01,0.25,-1.99,0.05,"down","yes"]
["chr17",45243118,45246604,"FMNL1",2.7,0.65,0.24,-2.05,0.05,"down","yes"]
["chr1",154206720,154220624,"C1orf43",2.88,0.7,0.24,-2.04,0.05,"down","yes"]
["chr9",35104142,35111423,"FAM214B",1.57,0.38,0.24,-2.05,0.05,"down","yes"]
["chr22",42869771,43015145,"PACSIN2",19.15,4.84,0.25,-1.98,0.05,"down","yes"]
["chr16",1309635,1327018,"UBE2I",2.03,0.5,0.25,-2.02,0.05,"down","yes"]
["chr7",66205199,66360443,"TPST1",4.52,1.12,0.25,-2.02,0.05,"down","yes"]
["chr7",100088982,100090238,"COPS6",6.1,1.48,0.24,-2.04,0.05,"down","yes"]
["chr10",101578882,101587421,"POLL",2.57,0.63,0.24,-2.04,0.05,"down","yes"]
["chr6",31580555,31582425,"LTB",80.76,20.53,0.25,-1.98,0.05,"down","yes"]
["chr14",105314744,105398147,"PACS2",1.22,0.3,0.25,-2.02,0.05,"down","yes"]
["chr19",15640900,15662825,"CYP4F3",14.65,3.73,0.25,-1.98,0.05,"down","yes"]
["chr22",27851669,27919268,"PITPNB",5.61,1.41,0.25,-1.99,0.05,"down","yes"]
["chr22",29883213,30026495,"MTMR3",5.79,1.47,0.25,-1.98,0.05,"down","yes"]
["chr8",86514427,86561498,"CPNE3",8.77,2.23,0.25,-1.97,0.05,"down","yes"]
["chr12",53711790,53727440,"CALCOCO1",8.73,2.21,0.25,-1.98,0.05,"down","yes"]
["chr6",26402250,26412920,"BTN3A1",1.97,0.47,0.24,-2.06,0.05,"down","yes"]
["chr8",63168553,63212786,"YTHDF3",7.92,2.02,0.26,-1.97,0.05,"down","yes"]
["chr9",4711155,4741318,"AK3",3.44,0.86,0.25,-1.99,0.05,"down","yes"]
["chr3",187721377,187745725,"BCL6",6.92,1.75,0.25,-1.98,0.05,"down","yes"]
["chr2",99169445,99181050,"MITD1",5.18,1.23,0.24,-2.08,0.05,"down","yes"]
["chr12",8513540,8522366,"CLEC4D",2.61,0.64,0.24,-2.03,0.05,"down","yes"]
["chrX",30653478,30729170,"GK",10.18,2.59,0.25,-1.98,0.05,"down","yes"]
["chr20",50292720,50314922,"LINC01270",2.22,0.55,0.25,-2.01,0.05,"down","yes"]
["chr6",36594368,36600881,"SRSF3",2.43,0.59,0.24,-2.04,0.05,"down","yes"]
["chr17",63774189,63819316,"DDX42",9.56,2.45,0.26,-1.96,0.05,"down","yes"]
["chr9",87497881,87708628,"DAPK1",4.04,1.03,0.26,-1.97,0.05,"down","yes"]
["chr15",44288760,44415757,"CASC4",7.3,1.87,0.26,-1.97,0.05,"down","yes"]
["chr3",25719270,25783414,"NGLY1",1.08,0.26,0.24,-2.05,0.05,"down","yes"]
["chr1",17066761,17119435,"PADI2",17.69,4.56,0.26,-1.96,0.05,"down","yes"]
["chr4",158124604,158172736,"FAM198B",1.73,0.44,0.25,-1.98,0.05,"down","yes"]
["chr9",39072767,39288138,"CNTNAP3",1.98,0.5,0.25,-1.99,0.05,"down","yes"]
["chr8",100918683,100951449,"YWHAZ",10.36,2.66,0.26,-1.96,0.05,"down","yes"]
["chr16",74451959,74607094,"GLG1",14.02,3.61,0.26,-1.96,0.05,"down","yes"]
["chr2",63050802,63057836,"OTX1",1.51,0.37,0.24,-2.03,0.05,"down","yes"]
["chr19",14619117,14674918,"ADGRE3",3.05,0.77,0.25,-1.99,0.05,"down","yes"]
["chr1",23970364,23980319,"SRSF10",4.3,1.07,0.25,-2,0.05,"down","yes"]
["chr1",2189548,2194774,"FAAP20",4.63,1.13,0.24,-2.04,0.05,"down","yes"]
["chr1",244850300,244864537,"HNRNPU",3.27,0.84,0.26,-1.96,0.05,"down","yes"]
["chr2",152651593,152717981,"PRPF40A",6.62,1.72,0.26,-1.95,0.05,"down","yes"]
["chrX",71910818,72153286,"NHSL2",5.31,1.38,0.26,-1.95,0.05,"down","yes"]
["chr3",155079647,155183708,"MME",6.85,1.77,0.26,-1.95,0.05,"down","yes"]
["chr12",53441741,53475553,"PCBP2",4.67,1.2,0.26,-1.97,0.05,"down","yes"]
["chr5",150053291,150113372,"CSF1R",15.28,3.98,0.26,-1.94,0.05,"down","yes"]
["chr1",156934840,157045370,"ARHGEF11",1.19,0.3,0.25,-1.97,0.05,"down","yes"]
["chr10",121743195,121927938,"ATE1",2.03,0.51,0.25,-2.01,0.05,"down","yes"]
["chr3",149813228,149960833,"RNF13",8.92,2.28,0.26,-1.97,0.05,"down","yes"]
["chr16",1776712,1782820,"SPSB3",12.4,3.22,0.26,-1.94,0.05,"down","yes"]
["chr1",198638874,198759289,"PTPRC",40.47,10.61,0.26,-1.93,0.05,"down","yes"]
["chr8",107249493,107498055,"ANGPT1",1.48,0.38,0.25,-1.98,0.05,"down","yes"]
["chr15",63277554,63309126,"APH1B",4.7,1.22,0.26,-1.94,0.05,"down","yes"]
["chr14",95709968,95714196,"TCL1A",2.04,0.49,0.24,-2.05,0.05,"down","yes"]
["chr22",16602044,16653809,"TPTEP1",1.22,0.31,0.25,-1.98,0.05,"down","yes"]
["chr1",205228176,205273343,"TMCC2",3.3,0.85,0.26,-1.95,0.05,"down","yes"]
["chr15",44711517,44718067,"B2M",36.67,9.58,0.26,-1.94,0.05,"down","yes"]
["chr10",110871791,110898127,"PDCD4",19.99,5.23,0.26,-1.93,0.05,"down","yes"]
["chr21",37225472,37267346,"DSCR3",4.66,1.17,0.25,-1.99,0.05,"down","yes"]
["chr2",219251194,219253354,"TUBA4A",8.28,2.08,0.25,-1.99,0.05,"down","yes"]
["chr11",66268533,66277492,"RAB1B",130.52,34.37,0.26,-1.93,0.05,"down","yes"]
["chr14",65075127,65102519,"MAX",1.48,0.37,0.25,-2.02,0.05,"down","yes"]
["chr3",129648103,129893592,"TMCC1",8.89,2.34,0.26,-1.93,0.05,"down","yes"]
["chr16",2752329,2771412,"SRRM2",29.91,7.9,0.26,-1.92,0.05,"down","yes"]
["chr14",90397032,90405607,"CALM1",3.61,0.91,0.25,-1.98,0.05,"down","yes"]

{"sheet":"Table 10","index":9,"n_rows":28,"n_cols":17,"rows_kept":28}
["chr","start","end","gene_name","FPKM.T1","FPKM.T2","foldChange.x","foldChange2.x","qval.x","regulation","significant.x","FPKM.T3","FPKM.T4","foldChange.y","foldChange2.y","qval.y","significant.y"]
["chr10",102133030,102150325,"PPRC1",0.2,3.63,18.26,4.19,0,"up","yes",0.7,5.18,7.41,2.89,0,"yes"]
["chr12",49791146,49828425,"NCKAP5L",0.18,2.69,14.77,3.88,0,"up","yes",0.38,2.66,6.92,2.79,0,"yes"]
["chr12",120534365,120577594,"RNF10",1.19,11.69,9.82,3.3,0,"up","yes",0.7,8.74,12.43,3.64,0,"yes"]
["chr12",123295905,123364828,"SBNO1",0.88,7.45,8.44,3.08,0,"up","yes",0.24,2.02,8.46,3.08,0,"yes"]
["chr6",33420255,33451842,"SYNGAP1",0.25,1.98,7.99,3,0,"up","yes",0.45,2.54,5.64,2.5,0.01,"yes"]
["chr20",51386957,51542719,"NFATC2",0.94,7,7.42,2.89,0,"up","yes",0.91,6.99,7.67,2.94,0,"yes"]
["chr9",112218604,112333620,"PTBP3",0.27,1.98,7.31,2.87,0.01,"up","yes",0.39,4.7,12.16,3.6,0,"yes"]
["chr1",24643308,24671595,"SRRM1",0.34,2.52,7.45,2.9,0.01,"up","yes",2.34,14.07,6.01,2.59,0,"yes"]
["chr19",41264417,41306991,"HNRNPUL1",0.56,3.91,7.01,2.81,0.01,"up","yes",5.46,36.59,6.69,2.74,0,"yes"]
["chr9",77177445,77421541,"VPS13A",0.27,1.82,6.76,2.76,0.01,"up","yes",0.19,1.12,5.93,2.57,0,"yes"]
["chr17",35010042,35089264,"AC004223.3",0.3,2.14,7.09,2.82,0.01,"up","yes",0.9,5.5,6.08,2.61,0,"yes"]
["chr12",49185010,49186864,"TUBA1A",3.14,20.89,6.65,2.73,0.01,"up","yes",0.69,16.33,23.81,4.57,0,"yes"]
["chr11",46347588,46380367,"DGKZ",0.28,1.93,6.84,2.77,0.01,"up","yes",0.77,5.28,6.85,2.78,0,"yes"]
["chr1",42682987,42702349,"YBX1",10.7,65.08,6.08,2.6,0.01,"up","yes",8.03,162.49,20.23,4.34,0,"yes"]
["chr17",40062899,40092627,"THRA",0.23,1.43,6.3,2.65,0.01,"up","yes",0.6,3.8,6.34,2.66,0,"yes"]
["chr16",18782968,18790362,"RPS15A",222.05,8.42,0.04,-4.72,0,"down","yes",80.9,12.63,0.16,-2.68,0,"yes"]
["chr11",65120630,65122057,"FAU",65.35,2.49,0.04,-4.71,0,"down","yes",7.97,1.11,0.14,-2.85,0,"yes"]
["chr10",5765954,5813411,"GDI2",30.29,2.6,0.09,-3.54,0,"down","yes",43.47,3.83,0.09,-3.5,0,"yes"]
["chr12",108288044,108339317,"CMKLR1",1.71,0.14,0.08,-3.63,0,"down","yes",2.37,0.26,0.11,-3.19,0,"yes"]
["chr5",140631728,140633701,"CD14",27.29,3.03,0.11,-3.17,0,"down","yes",47.73,1.82,0.04,-4.72,0,"yes"]
["chr16",18781295,18790334,"RPS15A",119.78,13.75,0.11,-3.12,0,"down","yes",63.68,6.93,0.11,-3.2,0,"yes"]
["chr10",97356701,97373593,"RRP12",2.55,0.39,0.15,-2.72,0,"down","yes",6.02,0.8,0.13,-2.91,0,"yes"]
["chr2",101001715,101007267,"RPL31",5.14,0.78,0.15,-2.72,0,"down","yes",4.52,0.74,0.16,-2.62,0.01,"yes"]
["chr1",161541765,161550623,"FCGR3A",61.12,9.99,0.16,-2.61,0,"down","yes",34.58,6.05,0.18,-2.51,0.01,"yes"]
["chr10",103088060,103181329,"NT5C2",5.5,0.95,0.17,-2.53,0,"down","yes",2.81,0.31,0.11,-3.19,0,"yes"]
["chrX",119786506,119791595,"RPL39",3.33,0.56,0.17,-2.58,0,"down","yes",7.9,0.33,0.04,-4.58,0,"yes"]
["chr11",65096227,65108399,"VPS51",6.37,1.12,0.18,-2.51,0.01,"down","yes",10.17,1.12,0.11,-3.19,0,"yes"]

{"sheet":"Table 11","index":10,"n_rows":31,"n_cols":9,"rows_kept":31}
["ID","Description","GeneRatio","BgRatio","pvalue","p.adjust","qvalue","geneID","Count"]
["GO:0019083","viral transcription","30/819","152/14614",{"v":1.2169566680077e-09,"d":"1.22E-09"},{"v":4.52987618024944e-06,"d":"4.53E-06"},{"v":4.35558090013647e-06,"d":"4.36E-06"},"RPS15/POLR2A/RPL15/POM121C/EP300/ZFP36/POM121/RPS3A/RPS5/RPL35/RPL9/RPL34/CCNT1/RPL27/RANBP2/RPS16/POLR2K/RPS21/RPSA/RPS18/RPS7/RPS27/TARBP2/RPL18A/PSMC3/POLR2L/RPL27A/RPL31/RPS9/RPLP0",30]
["GO:0019080","viral gene expression","31/819","164/14614",{"v":1.95548291830323e-09,"d":"1.96E-09"},{"v":4.52987618024944e-06,"d":"4.53E-06"},{"v":4.35558090013647e-06,"d":"4.36E-06"},"RPS15/POLR2A/RPL15/POM121C/EP300/ZFP36/POM121/RPS3A/RPS5/RPL35/RPL9/RPL34/CCNT1/RPL27/RANBP2/RPS16/POLR2K/RPS21/RPSA/RPS18/EIF3A/RPS7/RPS27/TARBP2/RPL18A/PSMC3/POLR2L/RPL27A/RPL31/RPS9/RPLP0",31]
["GO:0000956","nuclear-transcribed mRNA catabolic process","31/819","167/14614",{"v":3.09429241035368e-09,"d":"3.09E-09"},{"v":4.77861891238953e-06,"d":"4.78E-06"},{"v":4.59475280021641e-06,"d":"4.59E-06"},"RPS15/LSM2/RPL15/ZFP36L1/ZFP36/TNRC6B/TNRC6C/SMG1/RPS3A/RPS5/RPL35/RPL9/ZFP36L2/PATL1/RPL34/RPL27/XRN1/PDE12/RPS16/RPS21/RPSA/RPS18/RPS7/RPS27/AGO1/RPL18A/WDR61/RPL27A/RPL31/RPS9/RPLP0",31]
["GO:0006614","SRP-dependent cotranslational protein targeting to membrane","20/819","79/14614",{"v":8.48598617395443e-09,"d":"8.49E-09"},{"v":9.82889348598272E-6,"d":"9.83E-06"},{"v":9.45070881267767e-06,"d":"9.45E-06"},"RPS15/RPL15/RPS3A/RPS5/RPL35/RPL9/RPL34/RPL27/RPS16/RPS21/RPSA/RPS18/RPS7/RPS27/RPL18A/TRAM2/RPL27A/RPL31/RPS9/RPLP0",20]
["GO:0006613","cotranslational protein targeting to membrane","20/819","81/14614",{"v":1.35054989059047e-08,"d":"1.35E-08"},{"v":1.25141952862113E-5,"d":"1.25E-05"},{"v":1.20326887094292e-05,"d":"1.20E-05"},"RPS15/RPL15/RPS3A/RPS5/RPL35/RPL9/RPL34/RPL27/RPS16/RPS21/RPSA/RPS18/RPS7/RPS27/RPL18A/TRAM2/RPL27A/RPL31/RPS9/RPLP0",20]
["GO:0045047","protein targeting to ER","20/819","83/14614",{"v":2.11541064567907E-8,"d":"2.12E-08"},{"v":1.63344958690519e-05,"d":"1.63E-05"},{"v":1.57059962324804e-05,"d":"1.57E-05"},"RPS15/RPL15/RPS3A/RPS5/RPL35/RPL9/RPL34/RPL27/RPS16/RPS21/RPSA/RPS18/RPS7/RPS27/RPL18A/TRAM2/RPL27A/RPL31/RPS9/RPLP0",20]
["GO:0070972","protein localization to endoplasmic reticulum","22/819","102/14614",{"v":3.69613711364468e-08,"d":"3.70E-08"},{"v":2.33524237642426e-05,"d":"2.34E-05"},{"v":2.24538965022719e-05,"d":"2.25E-05"},"RPS15/RPL15/SEC16A/RPS3A/RPS5/RPL35/RPL9/RPL34/RPL27/RPS16/RPS21/RPSA/RPS18/RPS7/RPS27/GBF1/RPL18A/TRAM2/RPL27A/RPL31/RPS9/RPLP0",22]
["GO:0072599","establishment of protein localization to endoplasmic reticulum","20/819","86/14614",{"v":4.03236326600347e-08,"d":"4.03E-08"},{"v":2.33524237642426e-05,"d":"2.34E-05"},{"v":2.24538965022719e-05,"d":"2.25E-05"},"RPS15/RPL15/RPS3A/RPS5/RPL35/RPL9/RPL34/RPL27/RPS16/RPS21/RPSA/RPS18/RPS7/RPS27/RPL18A/TRAM2/RPL27A/RPL31/RPS9/RPLP0",20]
["GO:0006612","protein targeting to membrane","24/819","135/14614",{"v":4.2785246094563E-7,"d":"4.28E-07"},0.000220248939062345,2.11774457862211E-4,"RPS15/RPL15/STOM/RPS3A/RPS5/RPL35/RPL9/RPL34/RPL27/RPS16/MICALL1/RPS21/RPSA/RPS18/RPS7/RPS27/RPL18A/MIEF1/TRAM2/TCAF1/RPL27A/RPL31/RPS9/RPLP0",24]
["GO:0000184","nuclear-transcribed mRNA catabolic process, nonsense-mediated decay","20/819","101/14614",{"v":6.63186443357433e-07,"d":"6.63E-07"},3.07254279207499E-4,0.000295432108240911,"RPS15/RPL15/SMG1/RPS3A/RPS5/RPL35/RPL9/RPL34/RPL27/RPS16/RPS21/RPSA/RPS18/RPS7/RPS27/RPL18A/RPL27A/RPL31/RPS9/RPLP0",20]
["GO:0090150","establishment of protein localization to membrane","34/819","243/14614",{"v":7.44990811872611e-07,"d":"7.45E-07"},3.13776584673255E-4,3.01703456061712E-4,"YWHAG/RPS15/RPL15/MACF1/MAIP1/STOM/SEC16A/AFDN/RPS3A/RPS5/RPL35/RPL9/MAL/RPL34/LYPLA1/RPL27/RILPL2/RPS16/MICALL1/RPS21/RPSA/RPS18/RPS7/RPS27/RPL18A/SPTBN1/MIEF1/TRAM2/TCAF1/ASNA1/RPL27A/RPL31/RPS9/RPLP0",34]
["GO:0006413","translational initiation","25/819","157/14614",{"v":2.07395135888166E-6,"d":"2.07E-06"},0.000782068052545491,0.00075197655227885,"RPS15/RPL15/RPS3A/RPS5/RPL35/RPL9/RPL34/RPL27/PAIP2/ALKBH1/RPS16/RPS21/RPSA/RPS18/EIF3A/RPS7/RPS27/LARP1/RPL18A/EIF4E3/RPL27A/RPL31/EIF4G3/RPS9/RPLP0",25]
["GO:0006402","mRNA catabolic process","37/819","289/14614",{"v":2.19444953228823e-06,"d":"2.19E-06"},0.000782068052545491,0.00075197655227885,"ALKBH5/RPS15/LSM2/RPL15/ZFP36L1/ZFP36/TNRC6B/TNRC6C/SMG1/RPS3A/RPS5/ROCK2/RPL35/RPL9/ZFP36L2/PATL1/RPL34/RPL27/XRN1/PDE12/RPS16/RPS21/RPSA/RPS18/RPS7/RPS27/LARP1/AGO1/RPL18A/PSMC3/WDR61/RPL27A/RPL31/RPS9/CARHSP1/TIRAP/RPLP0",37]
["GO:0006401","RNA catabolic process","39/819","316/14614",{"v":2.91806611190727e-06,"d":"2.92E-06"},0.0009656714497476,0.000928515472600871,"RNASE6/ALKBH5/RPS15/LSM2/RPL15/ZFP36L1/ZFP36/TNRC6B/TNRC6C/SMG1/RPS3A/RPS5/ROCK2/RPL35/RPL9/ZFP36L2/PATL1/RPL34/RPL27/XRN1/PDE12/RPS16/RPS21/RPSA/RPS18/RPS7/RPS27/LARP1/AGO1/RPL18A/RNASEH2A/PSMC3/WDR61/RPL27A/RPL31/RPS9/CARHSP1/TIRAP/RPLP0",39]
["GO:0030219","megakaryocyte differentiation","17/819","85/14614",{"v":3.92428078636421E-6,"d":"3.92E-06"},0.00121207952554836,1.16544254651883E-3,"RUNX1/HIST1H4H/KMT2C/KMT2A/SH2B3/ZNF385A/ZFPM1/EP300/TNRC6B/KMT2B/TNRC6C/KMT2E/MPIG6B/MED1/HIST2H4A/SETD1A/AGO1",17]
["GO:0006605","protein targeting","38/819","312/14614",{"v":5.35058707048305e-06,"d":"5.35E-06"},1.54932936859675E-3,0.00148971608436081,"YWHAG/PEX2/RPS15/RPL15/TOMM20/TOMM7/AKAP12/SORL1/HUWE1/STOM/AP4S1/RPS3A/RPS5/RPL35/RPL9/RPL34/RPL27/RPS16/MICALL1/RPS21/RPSA/NUDT19/RPS18/RPS7/RPS27/HAX1/RPL18A/MIEF1/TRAM2/TCAF1/KIF13B/HMGCL/RPL27A/TIMM17B/USP9X/RPL31/RPS9/RPLP0",38]
["GO:0072657","protein localization to membrane","51/819","481/14614",{"v":8.42706276647499e-06,"d":"8.43E-06"},0.00216990810731946,0.00208641691984867,"YWHAG/PLEKHF1/VAMP8/RPS15/RPL15/CRKL/LRP1/MACF1/MAIP1/STOM/RAPGEF2/SEC16A/AFDN/RPS3A/RPS5/ROCK2/LDLRAP1/RPL35/TMEM150A/RPL9/MAL/RPL34/LYPLA1/RPL27/RILPL2/RPS16/DNAJA3/MICALL1/DCHS1/DAG1/RPS21/RPSA/RPS18/PTCH1/MYO5A/RPS7/RPS27/RAB32/CRIPT/RPL18A/SPTBN1/MIEF1/TRAM2/TCAF1/ASNA1/EPHB2/RPL27A/RPL31/IFT20/RPS9/RPLP0",51]
["GO:0030099","myeloid cell differentiation","42/819","367/14614",{"v":8.43046534248874e-06,"d":"8.43E-06"},0.00216990810731946,0.00208641691984867,"CCR1/CEBPG/RUNX1/HIST1H4H/NOTCH2/KMT2C/CREBBP/FOS/KMT2A/ZFP36L1/SH2B3/ZNF385A/ZFPM1/EP300/CREB1/ZFP36/TNRC6B/CDK6/SNRK/CBFA2T3/KMT2B/FOXO3/TNRC6C/KMT2E/MPIG6B/SNX10/MED1/HIPK2/HIST2H4A/ADAR/LRRK1/PTBP3/MYH9/BCL6/IL23A/SETD1A/PDE1B/AGO1/HAX1/WDR61/PIK3CD/TIRAP",42]
["GO:0051568","histone H3-K4 methylation","11/819","45/14614",{"v":2.80769329239163e-05,"d":"2.81E-05"},0.00684633843350022,0.00658291302681516,"KMT2C/SETD1B/KMT2A/ASH1L/TET3/AUTS2/KMT2B/KMT2E/BCOR/SETD1A/WDR61",11]
["GO:0042330","taxis","50/819","492/14614",{"v":3.21916231275847e-05,"d":"3.22E-05"},0.007457189497505,0.00717026047768097,"PTAFR/CCR1/CX3CR1/CXCR1/FPR1/FPR2/S1PR1/SIAH1/FFAR2/C5AR1/NECTIN1/GPR18/WNK1/NOTCH1/CRKL/LRP1/EP300/CREB1/TMEM102/ADGRE2/PIP5K1C/CMKLR1/BCL11B/KLF7/S100A8/GAB1/PLXNA3/LYST/IL23A/ABCC1/CXCL8/MYCBP2/ALKBH1/PTPRJ/DAG1/IL17RA/SPTA1/SOS1/PTCH1/SCRIB/FEZ1/FLT1/GBF1/ITGA1/SPTBN1/ANGPT1/EPHB2/IRS2/PIK3CD/TIRAP",50]
["GO:0006935","chemotaxis","49/819","490/14614",{"v":5.81265271679629E-5,"d":"5.81E-05"},0.0128238190651987,0.0123303991466075,"PTAFR/CCR1/CX3CR1/CXCR1/FPR1/FPR2/S1PR1/SIAH1/FFAR2/C5AR1/NECTIN1/GPR18/WNK1/NOTCH1/CRKL/LRP1/CREB1/TMEM102/ADGRE2/PIP5K1C/CMKLR1/BCL11B/KLF7/S100A8/GAB1/PLXNA3/LYST/IL23A/ABCC1/CXCL8/MYCBP2/ALKBH1/PTPRJ/DAG1/IL17RA/SPTA1/SOS1/PTCH1/SCRIB/FEZ1/FLT1/GBF1/ITGA1/SPTBN1/ANGPT1/EPHB2/IRS2/PIK3CD/TIRAP",49]
["GO:0045652","regulation of megakaryocyte differentiation","13/819","68/14614",{"v":8.70447623279384e-05,"d":"8.70E-05"},0.0183308356302427,0.0176255231661165,"RUNX1/HIST1H4H/KMT2C/KMT2A/ZFPM1/EP300/TNRC6B/KMT2B/TNRC6C/KMT2E/HIST2H4A/SETD1A/AGO1",13]
["GO:0030595","leukocyte chemotaxis","22/819","163/14614",0.000113075631278372,0.0227773652049,0.0219009643739163,"CCR1/CXCR1/FPR2/S1PR1/FFAR2/C5AR1/GPR18/WNK1/TMEM102/ADGRE2/PIP5K1C/CMKLR1/S100A8/LYST/IL23A/CXCL8/IL17RA/FLT1/GBF1/ITGA1/PIK3CD/TIRAP",22]
["GO:0016569","covalent chromatin modification","40/819","392/14614",1.79290008600724E-4,0.0346104420769647,0.0332787419472923,"KDM6B/KMT2C/CREBBP/SETD1B/KMT2A/HCFC1/ASH1L/TET3/EP400/AUTS2/TRRAP/SKI/DOT1L/HUWE1/EP300/NACC2/KMT2B/KMT2E/ATXN7/TAF1/NCOA1/BCL6/BAZ2A/BCOR/PER2/KDM2A/ATF7IP/SUDS3/SETD1A/KDM7A/TET1/KANSL1/RCOR1/KAT6B/JARID2/ELK4/CBX8/WDR61/HDAC4/CCNB1",40]
["GO:0016570","histone modification","39/819","382/14614",2.12790712103603E-4,0.0383317115542933,0.0368568287679392,"KDM6B/KMT2C/CREBBP/SETD1B/KMT2A/HCFC1/ASH1L/TET3/EP400/AUTS2/TRRAP/SKI/DOT1L/HUWE1/EP300/NACC2/KMT2B/KMT2E/ATXN7/TAF1/NCOA1/BCL6/BAZ2A/BCOR/PER2/KDM2A/SUDS3/SETD1A/KDM7A/TET1/KANSL1/RCOR1/KAT6B/JARID2/ELK4/CBX8/WDR61/HDAC4/CCNB1",39]
["GO:0035855","megakaryocyte development","6/819","17/14614",2.20723783846913E-4,0.0383317115542933,0.0368568287679392,"SH2B3/ZNF385A/ZFPM1/EP300/MPIG6B/MED1",6]
["GO:0060326","cell chemotaxis","26/819","218/14614",2.2338791538224E-4,0.0383317115542933,0.0368568287679392,"CCR1/CXCR1/FPR2/S1PR1/FFAR2/C5AR1/GPR18/WNK1/NOTCH1/CRKL/TMEM102/ADGRE2/PIP5K1C/CMKLR1/S100A8/GAB1/LYST/IL23A/ABCC1/CXCL8/IL17RA/FLT1/GBF1/ITGA1/PIK3CD/TIRAP",26]
["GO:0045637","regulation of myeloid cell differentiation","26/819","219/14614",2.40346062314348E-4,0.0397686895250849,0.0382385163802377,"CCR1/RUNX1/HIST1H4H/NOTCH2/KMT2C/CREBBP/FOS/KMT2A/ZFP36L1/ZFPM1/EP300/CREB1/ZFP36/TNRC6B/CDK6/KMT2B/FOXO3/TNRC6C/KMT2E/MED1/HIST2H4A/IL23A/SETD1A/AGO1/HAX1/WDR61",26]
["GO:0098751","bone cell development","8/819","32/14614",0.000296727940704858,0.0460377927321199,0.0442664043628277,"NOTCH2/SH2B3/ZNF385A/ZFPM1/EP300/MPIG6B/MED1/LRRK1",8]
["GO:0030098","lymphocyte differentiation","32/819","297/14614",0.000298107874371595,0.0460377927321199,0.0442664043628277,"CEBPG/IRF2BP2/RUNX1/NOTCH2/GPR18/CHD7/ZFP36L1/ZMIZ1/ZFPM1/EP300/RUNX2/CDK6/CD40LG/CR1/PNP/BCL11B/RUNX3/PRDX2/ZFP36L2/PRKDC/NFATC2/BCL6/IL23A/DNAJA3/HLX/BCL3/PTPRJ/SOS1/IKZF3/ADA/HDAC4/PIK3CD",32]

{"sheet":"Table 12","index":11,"n_rows":37,"n_cols":9,"rows_kept":37}
["ID","Description","GeneRatio","BgRatio","pvalue","p.adjust","qvalue","geneID","Count"]
["GO:0002275","myeloid cell activation involved in immune response","59/667","473/14614",{"v":1.6350545568028E-12,"d":"1.64E-12"},{"v":3.46578583563221E-9,"d":"3.47E-09"},{"v":3.38400994056113e-09,"d":"3.38E-09"},"CD14/COTL1/ADGRG3/RHOG/TLR2/FCN1/PTPRN2/MGAM/TCN1/CD93/QPCT/MME/YPEL5/CLEC5A/ANXA3/GCA/S100A8/CLEC4D/SDCBP/CHI3L1/MMP9/NFAM1/HMOX1/MOSPD2/GAB2/TNFAIP6/ADGRE3/CXCR1/MMP8/PADI2/CD177/HP/LILRA2/GM2A/MMP25/DYSF/CRISPLD2/S100A9/CYSTM1/RAB31/PECAM1/LTF/PGLYRP1/SIGLEC9/PYGL/SCAMP1/IGF2R/CXCR2/LYN/MNDA/ATP6V1D/CEACAM3/S100A12/SURF4/DNASE1/SLC2A3/SLC11A1/ALAD/LAMP2",59]
["GO:0042119","neutrophil activation","56/667","436/14614",{"v":1.8858034992368e-12,"d":"1.89E-12"},{"v":3.46578583563221E-9,"d":"3.47E-09"},{"v":3.38400994056113e-09,"d":"3.38E-09"},"CD14/COTL1/ADGRG3/RHOG/TLR2/FCN1/PTPRN2/MGAM/TCN1/CD93/QPCT/MME/YPEL5/CLEC5A/ANXA3/GCA/S100A8/CLEC4D/SDCBP/CXCL8/CHI3L1/MMP9/NFAM1/MOSPD2/TNFAIP6/ADGRE3/CXCR1/MMP8/PADI2/CD177/HP/LILRA2/GM2A/MMP25/CRISPLD2/S100A9/CYSTM1/RAB31/PECAM1/LTF/PGLYRP1/SIGLEC9/PYGL/SCAMP1/IGF2R/CXCR2/MNDA/ATP6V1D/CEACAM3/S100A12/SURF4/DNASE1/SLC2A3/SLC11A1/ALAD/LAMP2",56]
["GO:0002283","neutrophil activation involved in immune response","55/667","427/14614",{"v":2.6798441427674e-12,"d":"2.68E-12"},{"v":3.46578583563221E-9,"d":"3.47E-09"},{"v":3.38400994056113e-09,"d":"3.38E-09"},"CD14/COTL1/ADGRG3/RHOG/TLR2/FCN1/PTPRN2/MGAM/TCN1/CD93/QPCT/MME/YPEL5/CLEC5A/ANXA3/GCA/S100A8/CLEC4D/SDCBP/CHI3L1/MMP9/NFAM1/MOSPD2/TNFAIP6/ADGRE3/CXCR1/MMP8/PADI2/CD177/HP/LILRA2/GM2A/MMP25/CRISPLD2/S100A9/CYSTM1/RAB31/PECAM1/LTF/PGLYRP1/SIGLEC9/PYGL/SCAMP1/IGF2R/CXCR2/MNDA/ATP6V1D/CEACAM3/S100A12/SURF4/DNASE1/SLC2A3/SLC11A1/ALAD/LAMP2",55]
["GO:0036230","granulocyte activation","56/667","442/14614",{"v":3.3023209486729e-12,"d":"3.30E-12"},{"v":3.46578583563221E-9,"d":"3.47E-09"},{"v":3.38400994056113e-09,"d":"3.38E-09"},"CD14/COTL1/ADGRG3/RHOG/TLR2/FCN1/PTPRN2/MGAM/TCN1/CD93/QPCT/MME/YPEL5/CLEC5A/ANXA3/GCA/S100A8/CLEC4D/SDCBP/CXCL8/CHI3L1/MMP9/NFAM1/MOSPD2/TNFAIP6/ADGRE3/CXCR1/MMP8/PADI2/CD177/HP/LILRA2/GM2A/MMP25/CRISPLD2/S100A9/CYSTM1/RAB31/PECAM1/LTF/PGLYRP1/SIGLEC9/PYGL/SCAMP1/IGF2R/CXCR2/MNDA/ATP6V1D/CEACAM3/S100A12/SURF4/DNASE1/SLC2A3/SLC11A1/ALAD/LAMP2",56]
["GO:0002446","neutrophil mediated immunity","55/667","436/14614",{"v":6.2020511335765e-12,"d":"6.20E-12"},{"v":5.20724213175083E-9,"d":"5.21E-09"},{"v":5.08437623455724e-09,"d":"5.08E-09"},"CD14/COTL1/ADGRG3/RHOG/TLR2/FCN1/PTPRN2/MGAM/TCN1/CD93/QPCT/MME/YPEL5/CLEC5A/ANXA3/GCA/S100A8/CLEC4D/SDCBP/CHI3L1/MMP9/NFAM1/MOSPD2/TNFAIP6/IRAK4/ADGRE3/CXCR1/MMP8/PADI2/CD177/HP/GM2A/MMP25/CRISPLD2/S100A9/CYSTM1/RAB31/PECAM1/LTF/PGLYRP1/SIGLEC9/PYGL/SCAMP1/IGF2R/CXCR2/MNDA/ATP6V1D/CEACAM3/S100A12/SURF4/DNASE1/SLC2A3/SLC11A1/ALAD/LAMP2",55]
["GO:0002444","myeloid leukocyte mediated immunity","58/667","481/14614",{"v":1.04233114341648E-11,"d":"1.04E-11"},{"v":7.29284356677061e-09,"d":"7.29E-09"},{"v":7.12076749555045e-09,"d":"7.12E-09"},"CD14/COTL1/ADGRG3/RHOG/TLR2/FCN1/PTPRN2/MGAM/TCN1/CD93/QPCT/MME/YPEL5/CLEC5A/ANXA3/GCA/S100A8/CLEC4D/SDCBP/CHI3L1/MMP9/NFAM1/HMOX1/MOSPD2/GAB2/TNFAIP6/IRAK4/ADGRE3/CXCR1/MMP8/PADI2/CD177/HP/GM2A/MMP25/CRISPLD2/S100A9/CYSTM1/RAB31/PECAM1/LTF/PGLYRP1/SIGLEC9/PYGL/SCAMP1/IGF2R/CXCR2/LYN/MNDA/ATP6V1D/CEACAM3/S100A12/SURF4/DNASE1/SLC2A3/SLC11A1/ALAD/LAMP2",58]
["GO:0043312","neutrophil degranulation","53/667","424/14614",{"v":2.17486543326589e-11,"d":"2.17E-11"},{"v":1.30429786983575E-8,"d":"1.30E-08"},{"v":1.27352270633645e-08,"d":"1.27E-08"},"CD14/COTL1/ADGRG3/RHOG/TLR2/FCN1/PTPRN2/MGAM/TCN1/CD93/QPCT/MME/YPEL5/CLEC5A/ANXA3/GCA/S100A8/CLEC4D/SDCBP/CHI3L1/MMP9/NFAM1/MOSPD2/TNFAIP6/ADGRE3/CXCR1/MMP8/PADI2/CD177/HP/GM2A/MMP25/CRISPLD2/S100A9/CYSTM1/RAB31/PECAM1/LTF/PGLYRP1/SIGLEC9/PYGL/SCAMP1/IGF2R/CXCR2/MNDA/ATP6V1D/CEACAM3/S100A12/SURF4/SLC2A3/SLC11A1/ALAD/LAMP2",53]
["GO:0043299","leukocyte degranulation","56/667","466/14614",{"v":2.76731837076844E-11,"d":"2.77E-11"},{"v":1.45215031506074e-08,"d":"1.45E-08"},{"v":1.41788654418057e-08,"d":"1.42E-08"},"CD14/COTL1/ADGRG3/RHOG/TLR2/FCN1/PTPRN2/MGAM/TCN1/CD93/QPCT/MME/YPEL5/CLEC5A/ANXA3/GCA/S100A8/CLEC4D/SDCBP/CHI3L1/MMP9/NFAM1/HMOX1/MOSPD2/GAB2/TNFAIP6/ADGRE3/CXCR1/MMP8/PADI2/CD177/HP/GM2A/MMP25/CRISPLD2/S100A9/CYSTM1/RAB31/PECAM1/LTF/PGLYRP1/SIGLEC9/PYGL/SCAMP1/IGF2R/CXCR2/LYN/MNDA/ATP6V1D/CEACAM3/S100A12/SURF4/SLC2A3/SLC11A1/ALAD/LAMP2",56]
["GO:0050663","cytokine secretion","26/667","190/14614",{"v":5.30378640650634e-07,"d":"5.30E-07"},0.000247392170383485,0.00024155490370685,"TLR5/CD14/TLR2/FCN1/IL1RAP/ANGPT1/NOD2/IL17RA/CLEC5A/PANX2/CPTP/IL1R2/CHI3L1/LRRK2/FFAR2/NLRP12/ABCA1/MMP8/LILRA2/DYSF/TLR4/SRGN/NLRC4/LYN/S100A12/TLR8",26]
["GO:0051770","positive regulation of nitric-oxide synthase biosynthetic process","6/667","13/14614",{"v":1.1517148874793E-5,"d":"1.15E-05"},0.00446811334066213,0.00436268733194712,"TLR2/NOD2/NAMPT/LRRK2/TLR4/MAP2K4",6]
["GO:0070266","necroptotic process","9/667","33/14614",{"v":1.17077767382762E-5,"d":"1.17E-05"},0.00446811334066213,0.00436268733194712,"SPATA2/CD14/PELI1/TLR4/FAS/IPMK/PYGL/ITPK1/FASLG",9]
["GO:0050707","regulation of cytokine secretion","21/667","164/14614",{"v":1.83942916607056e-05,"d":"1.84E-05"},0.00643493636597017,0.00628310278305154,"TLR5/CD14/TLR2/FCN1/IL1RAP/ANGPT1/NOD2/IL17RA/CLEC5A/PANX2/CPTP/IL1R2/LRRK2/FFAR2/NLRP12/MMP8/LILRA2/TLR4/SRGN/LYN/TLR8",21]
["GO:0097300","programmed necrotic cell death","9/667","37/14614",{"v":3.20579081947581e-05,"d":"3.21E-05"},0.00971559080555398,0.00948634953908559,"SPATA2/CD14/PELI1/TLR4/FAS/IPMK/PYGL/ITPK1/FASLG",9]
["GO:0050900","leukocyte migration","37/667","398/14614",{"v":3.24007316049919e-05,"d":"3.24E-05"},0.00971559080555398,0.00948634953908559,"S1PR1/CXCR4/DUSP1/CCR6/IGKV1D-39/ANGPT1/IL17RA/JCHAIN/S100A8/CCL4/CXCL8/IGHV2-5/MMP9/TREM1/GCSAM/HMOX1/MOSPD2/FFAR2/IRAK4/CXCR1/NLRP12/PADI2/CD177/CD99L2/DYSF/S100A9/SDC3/PECAM1/CXCR2/LYN/CEACAM3/IGHV3-23/S100A12/IGHV3-11/CMKLR1/TNFRSF10A/CXCR3",37]
["GO:0002221","pattern recognition receptor signaling pathway","21/667","174/14614",{"v":4.50269995236131E-5,"d":"4.50E-05"},0.0126015562666752,0.0123042200803473,"TLR5/CD14/TLR2/FCN1/UBE2D1/NOD2/S100A8/FFAR2/IRAK4/TRAF3/LILRA2/GFI1/PELI1/TLR4/S100A9/LTF/PGLYRP1/LYN/NLRP6/TAB3/TLR8",21]
["GO:0006919","activation of cysteine-type endopeptidase activity involved in apoptotic process","12/667","69/14614",{"v":5.97149241152167E-5,"d":"5.97E-05"},0.015079925490075,0.0147241116968862,"PMAIP1/S100A8/BCL2L13/MTCH1/NLRP12/HIP1/S100A9/FAS/NLRC4/TNFSF10/FASLG/TNFRSF10A",12]
["GO:0051767","nitric-oxide synthase biosynthetic process","6/667","17/14614",{"v":7.098564092757e-05,"d":"7.10E-05"},0.015079925490075,0.0147241116968862,"TLR2/NOD2/NAMPT/LRRK2/TLR4/MAP2K4",6]
["GO:0051769","regulation of nitric-oxide synthase biosynthetic process","6/667","17/14614",{"v":7.098564092757e-05,"d":"7.10E-05"},0.015079925490075,0.0147241116968862,"TLR2/NOD2/NAMPT/LRRK2/TLR4/MAP2K4",6]
["GO:0098543","detection of other organism","5/667","11/14614",{"v":7.16418110162236e-05,"d":"7.16E-05"},0.015079925490075,0.0147241116968862,"TLR2/NOD2/TLR4/PGLYRP1/NLRC4",5]
["GO:0050701","interleukin-1 secretion","10/667","50/14614",{"v":7.18433801337541e-05,"d":"7.18E-05"},0.015079925490075,0.0147241116968862,"NOD2/PANX2/CPTP/IL1R2/NLRP12/ABCA1/LILRA2/TLR4/NLRC4/TLR8",10]
["GO:0002224","toll-like receptor signaling pathway","17/667","132/14614",1.05084207396863E-4,0.0203664277270911,0.0198858778790133,"TLR5/CD14/TLR2/UBE2D1/S100A8/IRAK4/TRAF3/LILRA2/GFI1/PELI1/TLR4/S100A9/LTF/LYN/NLRP6/TAB3/TLR8",17]
["GO:0031349","positive regulation of defense response","38/667","437/14614",1.06732112909958E-4,0.0203664277270911,0.0198858778790133,"TLR5/CD14/CEBPB/TLR2/FCN1/UBE2D1/NOD2/IL17RA/PTGS2/S100A8/CLEC4D/LRRK2/NAPEPLD/LAG3/FFAR2/IRAK4/POLR3D/NLRP12/MMP8/TRAF3/LILRA2/GFI1/SLAMF6/ICAM3/PELI1/TLR4/PLSCR1/S100A9/TXK/LTF/PGLYRP1/NLRC4/LYN/MNDA/NLRP6/TAB3/S100A12/TLR8",38]
["GO:1990266","neutrophil migration","11/667","64/14614",0.000134565981956136,0.0240068025886366,0.0234403573832529,"S100A8/CXCL8/MOSPD2/IRAK4/CD177/CD99L2/DYSF/S100A9/PECAM1/CXCR2/S100A12",11]
["GO:0070265","necrotic cell death","9/667","44/14614",0.000137247084832606,0.0240068025886366,0.0234403573832529,"SPATA2/CD14/PELI1/TLR4/FAS/IPMK/PYGL/ITPK1/FASLG",9]
["GO:0097530","granulocyte migration","13/667","87/14614",0.000150413278512805,0.0252573977278703,0.0246614444854259,"IL17RA/S100A8/CXCL8/MOSPD2/IRAK4/CD177/CD99L2/DYSF/S100A9/PECAM1/CXCR2/S100A12/CMKLR1",13]
["GO:0045088","regulation of innate immune response","34/667","382/14614",0.000156841618372627,0.0253238889972418,0.0247263668802838,"TLR5/CD14/TLR2/FCN1/UBE2D1/NOD2/S100A8/CLEC4D/LAG3/FFAR2/IRAK4/POLR3D/TRAF3/LILRA2/GFI1/IFNGR2/SLAMF6/CLEC12B/ICAM3/PELI1/TLR4/PLSCR1/S100A9/TXK/LTF/PGLYRP1/NLRC4/LYN/SOCS3/MNDA/NLRP6/IFNGR1/TAB3/TLR8",34]
["GO:0030595","leukocyte chemotaxis","19/667","163/14614",0.000162964297034823,0.0253379303315625,0.0247400769065731,"S1PR1/CXCR4/DUSP1/CCR6/IL17RA/S100A8/CCL4/CXCL8/MOSPD2/FFAR2/CXCR1/PADI2/DYSF/S100A9/CXCR2/LYN/S100A12/CMKLR1/CXCR3",19]
["GO:0050715","positive regulation of cytokine secretion","15/667","112/14614",0.000170132781653831,0.025507764906528,0.0249059042015045,"CD14/TLR2/FCN1/IL1RAP/NOD2/IL17RA/CLEC5A/PANX2/LRRK2/FFAR2/NLRP12/MMP8/LILRA2/TLR4/TLR8",15]
["GO:0045089","positive regulation of innate immune response","30/667","324/14614",1.90766656645566E-4,0.0276151180895891,0.026963533973787,"TLR5/CD14/TLR2/FCN1/UBE2D1/NOD2/S100A8/CLEC4D/LAG3/FFAR2/IRAK4/POLR3D/TRAF3/LILRA2/GFI1/SLAMF6/ICAM3/PELI1/TLR4/PLSCR1/S100A9/TXK/LTF/PGLYRP1/NLRC4/LYN/MNDA/NLRP6/TAB3/TLR8",30]
["GO:0050727","regulation of inflammatory response","32/667","356/14614",0.000203236290424022,0.0276629150079638,0.0270102031145184,"SPATA2/CEBPB/IGKV1D-39/TLR2/SOCS5/NOD2/IL17RA/C4BPA/PTGS2/S100A8/IL1R2/LRRK2/NAPEPLD/IGHV2-5/MMP9/FFAR2/TNFAIP6/NLRP12/MMP8/IL2RA/CD46/TLR4/S100A9/HGF/PGLYRP1/LYN/SOCS3/NLRP6/IGHV3-23/S100A12/IGHV3-11/DNASE1",32]
["GO:0045589","regulation of regulatory T cell differentiation","7/667","28/14614",0.000204275932645754,0.0276629150079638,0.0270102031145184,"CTLA4/VSIR/LAG3/BCL6/IL2RA/CD46/NFATC2",7]
["GO:0006968","cellular defense response","9/667","47/14614",0.000233443907836854,0.0306249226593473,0.0299023216156812,"CCR6/ZNF148/CCR3/CLEC5A/PRF1/KLRG1/CXCR2/MNDA/NCF2",9]
["GO:0045066","regulatory T cell differentiation","7/667","29/14614",0.000258770671993303,0.0329187660917541,0.0321420413633786,"CTLA4/VSIR/LAG3/BCL6/IL2RA/CD46/NFATC2",7]
["GO:0032757","positive regulation of interleukin-8 production","8/667","39/14614",0.000315907943276216,0.0390053395845163,0.0380850009633927,"TLR5/CD14/TLR2/FCN1/NOD2/FFAR2/TLR4/TLR8",8]
["GO:0034121","regulation of toll-like receptor signaling pathway","10/667","60/14614",3.49590276749222E-4,0.0419308566226639,0.0409414898544804,"TLR5/CD14/TLR2/LILRA2/GFI1/PELI1/TLR4/LTF/LYN/NLRP6",10]
["GO:0060326","cell chemotaxis","22/667","218/14614",0.000415522561139252,0.0484545475461828,0.0473112530139254,"S1PR1/CXCR4/DUSP1/RHOG/CCR6/IL17RA/S100A8/CCL4/CXCL8/MOSPD2/FFAR2/CXCR1/PADI2/DYSF/S100A9/HGF/CXCR2/LYN/GAB1/S100A12/CMKLR1/CXCR3",22]